# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- RVT_2 PF07727.9 XP_011270974.1 - 2.6e-34 118.2 0.5 6.7e-34 116.9 0.1 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RING_2 PF13639.1 XP_011270975.1 - 3.2e-06 26.8 4.6 5.5e-06 26.1 3.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 XP_011270975.1 - 0.00014 21.4 3.0 0.00023 20.7 2.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 XP_011270975.1 - 0.0033 17.1 4.6 0.0053 16.4 3.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 XP_011270975.1 - 0.005 16.8 4.7 0.0093 15.9 3.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 XP_011270975.1 - 0.0064 16.1 3.3 0.017 14.7 2.3 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 XP_011270975.1 - 4.6 7.0 6.0 4 7.2 2.5 2.2 2 0 0 2 2 2 0 RING-type zinc-finger DUF4336 PF14234.1 XP_011270976.1 - 0.0066 15.6 0.0 2.6 7.1 0.0 2.9 3 0 0 3 3 3 3 Domain of unknown function (DUF4336) ArfGap PF01412.13 XP_011270977.1 - 2.8e-35 120.6 0.0 9.7e-35 118.8 0.0 1.9 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf adh_short_C2 PF13561.1 XP_011270978.1 - 4.9e-26 91.9 0.2 6.5e-26 91.5 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 XP_011270978.1 - 6.5e-21 74.9 1.7 8.3e-21 74.6 1.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 XP_011270978.1 - 9.2e-10 38.4 0.5 1.3e-09 38.0 0.3 1.1 1 0 0 1 1 1 1 KR domain PDZ PF00595.19 XP_011270978.1 - 0.035 14.2 0.3 0.069 13.3 0.2 1.5 1 0 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) Epimerase PF01370.16 XP_011270978.1 - 0.038 13.4 0.3 0.052 12.9 0.2 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family PA PF02225.17 XP_011270978.1 - 0.084 12.5 0.1 0.2 11.3 0.1 1.7 1 0 0 1 1 1 0 PA domain DAHP_synth_1 PF00793.15 XP_011270979.1 - 1e-97 326.1 0.0 1.2e-97 325.8 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family DUF948 PF06103.6 XP_011270980.1 - 9.2 6.2 11.4 38 4.2 0.4 3.6 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) Hat1_N PF10394.4 XP_011270981.1 - 0.028 14.4 0.9 0.042 13.9 0.7 1.2 1 0 0 1 1 1 0 Histone acetyl transferase HAT1 N-terminus MFS_1 PF07690.11 XP_011270984.1 - 6.3e-09 34.9 52.4 4.8e-07 28.8 36.4 3.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 XP_011270984.1 - 5.5e-08 31.8 4.6 5.5e-08 31.8 3.2 2.6 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 XP_011270984.1 - 3.7e-07 28.7 26.8 5.3e-07 28.2 18.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Transposase_mut PF00872.13 XP_011270985.1 - 1.5e-12 46.7 0.0 2.9e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Transposase, Mutator family MULE PF10551.4 XP_011270985.1 - 6.7e-10 39.0 0.1 2.6e-09 37.1 0.1 2.0 1 0 0 1 1 1 1 MULE transposase domain PIF1 PF05970.9 XP_011270986.1 - 2.9e-46 158.0 4.2 4.4e-46 157.4 2.9 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 XP_011270986.1 - 3.6e-07 29.9 0.0 2.5e-06 27.2 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 XP_011270986.1 - 1.4e-05 25.2 0.6 6e-05 23.1 0.1 2.2 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 XP_011270986.1 - 0.00011 21.7 0.4 0.3 10.5 0.3 3.4 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.1 XP_011270986.1 - 0.00025 21.8 1.1 0.0075 17.0 0.0 2.9 2 1 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.1 XP_011270986.1 - 0.00031 20.8 0.0 0.001 19.1 0.0 2.1 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_14 PF13173.1 XP_011270986.1 - 0.0005 19.9 1.0 0.0005 19.9 0.7 3.8 3 2 1 4 4 4 1 AAA domain AAA_18 PF13238.1 XP_011270986.1 - 0.00052 20.3 0.1 0.00052 20.3 0.1 3.2 3 1 1 4 4 3 1 AAA domain NTPase_1 PF03266.10 XP_011270986.1 - 0.00076 19.2 0.6 0.35 10.5 0.1 2.8 2 0 0 2 2 2 1 NTPase UPF0079 PF02367.12 XP_011270986.1 - 0.0041 16.7 0.4 0.015 14.9 0.0 2.0 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_10 PF12846.2 XP_011270986.1 - 0.007 15.8 0.4 2.3 7.5 0.0 2.8 2 0 0 2 2 2 1 AAA-like domain NACHT PF05729.7 XP_011270986.1 - 0.0088 15.7 0.0 0.027 14.1 0.0 1.8 1 0 0 1 1 1 1 NACHT domain ABC_tran PF00005.22 XP_011270986.1 - 0.016 15.5 3.2 0.017 15.4 0.2 2.5 3 0 0 3 3 2 0 ABC transporter DUF258 PF03193.11 XP_011270986.1 - 0.017 14.2 0.3 0.038 13.1 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_33 PF13671.1 XP_011270986.1 - 0.019 14.8 0.0 0.039 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 XP_011270986.1 - 0.019 14.4 0.0 0.037 13.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 XP_011270986.1 - 0.033 14.3 2.1 0.1 12.7 0.3 2.7 2 1 0 2 2 2 0 RNA helicase cobW PF02492.14 XP_011270986.1 - 0.035 13.5 0.6 0.095 12.1 0.2 1.9 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain T2SE PF00437.15 XP_011270986.1 - 0.06 12.2 0.1 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein CoaE PF01121.15 XP_011270986.1 - 0.069 12.5 0.3 1.3 8.3 0.0 2.5 3 0 0 3 3 3 0 Dephospho-CoA kinase AAA_16 PF13191.1 XP_011270986.1 - 0.084 12.8 0.1 0.23 11.4 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.24 XP_011270986.1 - 0.084 13.0 0.1 0.4 10.8 0.0 2.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 XP_011270986.1 - 0.095 12.4 0.3 0.93 9.2 0.1 2.5 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 XP_011270986.1 - 0.14 11.9 0.0 0.41 10.4 0.0 1.7 2 0 0 2 2 1 0 Part of AAA domain DOT1 PF08123.8 XP_011270988.1 - 9.1e-05 21.8 1.4 0.00015 21.1 1.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 DUF2358 PF10184.4 XP_011270988.1 - 0.15 12.0 5.7 0.18 11.7 0.9 2.9 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2358) FAM178 PF14816.1 XP_011270990.1 - 0.34 9.5 2.2 0.27 9.9 0.7 1.4 2 0 0 2 2 2 0 Family of unknown function, FAM178 NST1 PF13945.1 XP_011270990.1 - 1.2 9.1 10.0 1.6 8.7 6.9 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator zf-CCHC PF00098.18 XP_011270991.1 - 0.83 9.6 11.4 0.31 11.0 1.1 2.7 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.1 XP_011270991.1 - 7.9 6.2 9.7 5.9 6.6 2.9 2.5 1 1 1 2 2 2 0 Zinc knuckle Myb_DNA-bind_3 PF12776.2 XP_011270992.1 - 0.001 19.6 1.1 0.0046 17.5 0.8 2.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain PAT1 PF09770.4 XP_011270992.1 - 2.3 6.3 25.8 3.4 5.7 17.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TRAPP PF04051.11 XP_011270993.1 - 1.5e-36 125.2 0.0 1.8e-36 124.9 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Septin PF00735.13 XP_011270994.1 - 3.4e-94 315.0 1.4 7.5e-94 313.8 0.4 1.8 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 XP_011270994.1 - 3.7e-05 23.6 0.0 0.0001 22.2 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 XP_011270994.1 - 5.6e-05 23.0 2.2 0.0042 16.9 0.1 3.2 2 2 0 2 2 2 1 Dynamin family GTP_EFTU PF00009.22 XP_011270994.1 - 0.0013 18.1 0.2 0.0072 15.7 0.0 2.2 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 XP_011270994.1 - 0.0016 17.6 0.2 0.0064 15.6 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 XP_011270994.1 - 0.0032 18.2 0.5 0.04 14.7 0.0 2.9 3 1 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.13 XP_011270994.1 - 0.0095 15.4 0.6 0.017 14.5 0.0 1.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family AIG1 PF04548.11 XP_011270994.1 - 0.0098 15.0 0.2 2.7 7.0 0.0 2.3 2 0 0 2 2 2 1 AIG1 family Viral_helicase1 PF01443.13 XP_011270994.1 - 0.01 15.4 0.0 0.16 11.4 0.0 2.4 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 XP_011270994.1 - 0.01 16.0 0.0 0.021 14.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 XP_011270994.1 - 0.01 15.8 0.1 0.046 13.7 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.1 XP_011270994.1 - 0.01 16.1 0.2 0.039 14.2 0.0 2.1 2 0 0 2 2 1 0 AAA domain KAP_NTPase PF07693.9 XP_011270994.1 - 0.011 14.7 0.0 0.25 10.3 0.0 2.4 2 0 0 2 2 2 0 KAP family P-loop domain Pox_A32 PF04665.7 XP_011270994.1 - 0.023 14.0 0.0 0.041 13.1 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_29 PF13555.1 XP_011270994.1 - 0.029 13.8 0.0 0.059 12.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MobB PF03205.9 XP_011270994.1 - 0.037 13.7 0.0 0.087 12.5 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Synaptobrevin PF00957.16 XP_011270994.1 - 0.042 13.4 0.5 0.1 12.1 0.3 1.6 1 0 0 1 1 1 0 Synaptobrevin AAA_10 PF12846.2 XP_011270994.1 - 0.045 13.1 0.7 0.13 11.6 0.0 2.1 2 1 0 2 2 2 0 AAA-like domain AAA_14 PF13173.1 XP_011270994.1 - 0.052 13.4 0.3 0.17 11.7 0.0 2.0 2 0 0 2 2 1 0 AAA domain TrwB_AAD_bind PF10412.4 XP_011270994.1 - 0.053 12.1 0.3 0.089 11.3 0.2 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_33 PF13671.1 XP_011270994.1 - 0.054 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 XP_011270994.1 - 0.057 13.3 0.1 0.057 13.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 XP_011270994.1 - 0.058 12.2 0.9 0.082 11.7 0.1 1.5 2 0 0 2 2 2 0 Type II/IV secretion system protein Miro PF08477.8 XP_011270994.1 - 0.076 13.5 0.0 0.26 11.7 0.0 2.0 1 1 0 1 1 1 0 Miro-like protein cobW PF02492.14 XP_011270994.1 - 0.11 11.9 0.2 0.33 10.3 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.1 XP_011270994.1 - 0.12 11.9 0.4 0.27 10.8 0.3 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 XP_011270994.1 - 0.12 12.0 0.2 0.28 10.8 0.2 1.6 1 0 0 1 1 1 0 NTPase AAA_19 PF13245.1 XP_011270994.1 - 0.13 12.0 0.0 0.34 10.6 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain HAP1_N PF04849.8 XP_011270995.1 - 0.0039 16.1 4.6 0.0039 16.1 3.2 1.6 2 0 0 2 2 2 1 HAP1 N-terminal conserved region FliJ PF02050.11 XP_011270995.1 - 0.029 14.4 1.1 0.073 13.1 0.8 1.6 1 0 0 1 1 1 0 Flagellar FliJ protein Herpes_BBRF1 PF04793.7 XP_011270995.1 - 0.035 12.8 0.2 0.074 11.7 0.1 1.5 2 0 0 2 2 2 0 BRRF1-like protein DivIC PF04977.10 XP_011270995.1 - 0.04 13.4 0.3 0.11 11.9 0.2 1.8 1 0 0 1 1 1 0 Septum formation initiator bZIP_1 PF00170.16 XP_011270995.1 - 0.18 11.7 1.9 0.43 10.5 1.3 1.6 1 0 0 1 1 1 0 bZIP transcription factor YjeF_N PF03853.10 XP_011270996.1 - 3.1e-25 88.7 0.0 4.2e-25 88.2 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus Cytidylate_kin2 PF13189.1 XP_011270996.1 - 0.072 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase-like family Retrotrans_gag PF03732.12 XP_011270997.1 - 1.4e-15 57.1 0.5 1.7e-14 53.6 0.0 2.7 3 0 0 3 3 3 1 Retrotransposon gag protein zf-CCHC PF00098.18 XP_011270997.1 - 8.6e-07 28.5 0.6 1.3e-06 28.0 0.4 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 XP_011270997.1 - 0.00051 19.4 0.2 0.0011 18.3 0.1 1.5 1 0 0 1 1 1 1 Zinc knuckle Bromo_TP PF07524.8 XP_011270997.1 - 0.0096 15.6 0.2 2 8.2 0.0 2.4 2 0 0 2 2 2 2 Bromodomain associated SCAN PF02023.12 XP_011270997.1 - 0.016 14.6 0.7 0.091 12.2 0.0 2.4 3 0 0 3 3 3 0 SCAN domain zf-CCHC_4 PF14392.1 XP_011270997.1 - 0.022 14.4 0.4 0.057 13.1 0.3 1.7 1 0 0 1 1 1 0 Zinc knuckle Asp_protease_2 PF13650.1 XP_011270998.1 - 9.2e-10 38.9 0.0 1.9e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 XP_011270998.1 - 6.4e-08 32.2 0.0 1.1e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Peptidase_A2B PF12384.3 XP_011270998.1 - 2.9e-06 26.7 0.0 5.4e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Ty3 transposon peptidase Asp_protease PF09668.5 XP_011270998.1 - 1.6e-05 24.4 0.0 2.8e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease DUF1758 PF05585.7 XP_011270998.1 - 0.016 14.7 0.0 0.03 13.8 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) RVP PF00077.15 XP_011270998.1 - 0.027 14.3 0.1 0.54 10.2 0.0 2.6 2 0 0 2 2 2 0 Retroviral aspartyl protease RVP_2 PF08284.6 XP_011270998.1 - 0.063 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC_4 PF14392.1 XP_011270999.1 - 2.3 7.9 10.1 1.9 8.2 3.2 2.5 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC PF00098.18 XP_011270999.1 - 9.4 6.3 15.1 0.27 11.2 1.1 2.6 2 1 1 3 3 3 0 Zinc knuckle Carn_acyltransf PF00755.15 XP_011271000.1 - 4.1e-171 570.0 4.1 3.7e-155 517.3 1.0 2.0 2 0 0 2 2 2 2 Choline/Carnitine o-acyltransferase Ras PF00071.17 XP_011271002.1 - 2.6e-54 182.9 0.0 3e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 XP_011271002.1 - 3.9e-14 53.1 0.0 7.1e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 XP_011271002.1 - 1e-05 24.8 0.0 1.2e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 XP_011271002.1 - 0.14 11.2 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PAPS_reduct PF01507.14 XP_011271003.1 - 1.2e-42 145.7 0.0 1.6e-42 145.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Y_phosphatase PF00102.22 XP_011271004.1 - 6e-53 179.5 3.2 6e-53 179.5 2.2 2.0 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Rhodanese PF00581.15 XP_011271004.1 - 1.4e-10 41.5 0.0 9.3e-10 38.8 0.0 2.3 2 0 0 2 2 2 1 Rhodanese-like domain DSPc PF00782.15 XP_011271004.1 - 0.00023 20.7 0.0 0.00023 20.7 0.0 3.0 3 1 0 3 3 3 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 XP_011271004.1 - 0.02 15.1 0.1 0.046 13.9 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family CENP-Q PF13094.1 XP_011271005.1 - 2.7 8.0 24.1 0.94 9.4 13.6 2.3 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit LsmAD PF06741.8 XP_011271006.1 - 8.1e-28 96.3 1.0 8.1e-28 96.3 0.7 4.0 4 1 1 5 5 5 1 LsmAD domain SM-ATX PF14438.1 XP_011271006.1 - 8.7e-05 22.3 0.3 0.00056 19.7 0.0 2.5 2 0 0 2 2 2 1 Ataxin 2 SM domain PAM2 PF07145.10 XP_011271006.1 - 0.0058 16.0 0.6 0.021 14.2 0.4 2.1 1 0 0 1 1 1 1 Ataxin-2 C-terminal region CRAL_TRIO_2 PF13716.1 XP_011271007.1 - 6.7e-27 94.2 2.8 6.7e-27 94.2 2.0 2.6 3 0 0 3 3 3 1 Divergent CRAL/TRIO domain RhoGAP PF00620.22 XP_011271007.1 - 3.3e-07 30.0 0.1 1.1e-06 28.3 0.0 1.8 2 0 0 2 2 2 1 RhoGAP domain RasGEF PF00617.14 XP_011271008.1 - 4.1e-47 160.3 2.8 1e-46 159.0 2.0 1.7 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 XP_011271008.1 - 3.1e-12 46.4 1.3 3.1e-12 46.4 0.9 3.0 3 0 0 3 3 3 1 RasGEF N-terminal motif SH3_1 PF00018.23 XP_011271008.1 - 0.00057 19.2 0.0 0.0015 17.9 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 XP_011271008.1 - 0.0045 16.5 0.0 0.01 15.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Aconitase PF00330.15 XP_011271009.1 - 4.8e-174 579.2 0.2 2.1e-173 577.1 0.0 2.0 2 1 0 2 2 2 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 XP_011271009.1 - 1.4e-39 135.1 0.1 3.4e-39 133.9 0.0 1.7 2 0 0 2 2 2 1 Aconitase C-terminal domain DUF2305 PF10230.4 XP_011271010.1 - 0.019 14.4 0.6 0.037 13.4 0.4 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) ING PF12998.2 XP_011271010.1 - 0.29 11.4 7.2 0.96 9.7 0.2 2.6 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DASH_Duo1 PF08651.5 XP_011271010.1 - 0.35 10.4 5.3 6.1 6.4 0.0 2.7 3 0 0 3 3 3 0 DASH complex subunit Duo1 DUF4298 PF14131.1 XP_011271010.1 - 0.47 10.3 5.2 0.96 9.3 1.9 2.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4298) Peptidase_M24 PF00557.19 XP_011271011.1 - 3.8e-48 163.8 0.2 4.5e-48 163.5 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Holin_LLH PF09682.5 XP_011271011.1 - 0.039 14.0 0.8 0.097 12.8 0.1 2.0 2 0 0 2 2 2 0 Phage holin protein (Holin_LLH) DUF2732 PF10809.3 XP_011271011.1 - 0.08 12.4 0.1 0.2 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2732) Ribosomal_S21 PF01165.15 XP_011271012.1 - 7e-08 31.7 0.5 7e-08 31.7 0.3 2.0 2 0 0 2 2 2 1 Ribosomal protein S21 Fib_alpha PF08702.5 XP_011271012.1 - 1.3 9.1 4.9 2.2 8.4 1.1 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Flp_N PF03930.9 XP_011271013.1 - 0.011 15.4 0.1 0.026 14.2 0.1 1.7 1 0 0 1 1 1 0 Recombinase Flp protein N-terminus ADH_N PF08240.7 XP_011271015.1 - 6.4e-27 93.4 0.3 1.3e-26 92.4 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 XP_011271015.1 - 5.6e-11 42.1 1.3 2.6e-08 33.4 0.4 2.3 1 1 1 2 2 2 2 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 XP_011271015.1 - 0.0027 17.3 0.1 0.0027 17.3 0.1 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated FANCL_C PF11793.3 XP_011271015.1 - 0.07 13.0 0.3 0.13 12.1 0.2 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain Aa_trans PF01490.13 XP_011271016.1 - 4.4e-100 335.0 26.0 5.4e-100 334.7 18.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 XP_011271016.1 - 9.7e-14 50.9 16.3 9.7e-14 50.9 11.3 1.6 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family SH3_9 PF14604.1 XP_011271017.1 - 6.9e-09 35.1 0.1 3.2e-08 33.0 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 XP_011271017.1 - 8.9e-09 34.5 0.0 1.5e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 XP_011271017.1 - 1.4e-08 34.1 0.2 3e-08 33.0 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain Exo_endo_phos PF03372.18 XP_011271018.1 - 2.8e-05 24.2 0.0 3.2e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Peptidase_M3 PF01432.15 XP_011271018.1 - 0.022 13.7 0.6 0.048 12.7 0.0 1.7 2 0 0 2 2 2 0 Peptidase family M3 HhH-GPD PF00730.20 XP_011271019.1 - 1.3e-18 67.2 0.0 2.3e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 XP_011271019.1 - 1.3e-06 27.7 0.0 5.9e-06 25.6 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix motif Na_Ca_ex PF01699.19 XP_011271020.1 - 3.1e-27 94.9 24.7 1e-14 54.3 5.2 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Innate_immun PF12782.2 XP_011271020.1 - 1.5 7.9 5.1 2.1 7.4 3.6 1.1 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family SKIP_SNW PF02731.10 XP_011271022.1 - 6.3e-58 194.6 8.7 6.3e-58 194.6 6.0 2.8 3 0 0 3 3 3 1 SKIP/SNW domain RNase_P_Rpp14 PF01900.14 XP_011271023.1 - 2.9e-34 117.1 0.6 3.9e-34 116.7 0.4 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family HNF-1_N PF04814.8 XP_011271026.1 - 0.00071 19.7 0.2 0.00093 19.3 0.1 1.3 1 0 0 1 1 1 1 Hepatocyte nuclear factor 1 (HNF-1), N terminus zf-RING_UBOX PF13445.1 XP_011271026.1 - 0.11 12.2 1.7 1.8 8.3 0.6 2.5 2 0 0 2 2 2 0 RING-type zinc-finger DEAD PF00270.24 XP_011271027.1 - 2.7e-08 33.4 0.0 5.9e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 XP_011271027.1 - 4.3e-08 32.8 0.0 1.4e-07 31.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 XP_011271027.1 - 5.8e-05 22.9 0.8 0.00049 19.9 0.2 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Peptidase_C48 PF02902.14 XP_011271028.1 - 2e-08 34.1 0.5 2e-08 34.1 0.3 2.8 3 1 0 3 3 3 1 Ulp1 protease family, C-terminal catalytic domain Tom37_C PF11801.3 XP_011271028.1 - 0.11 12.3 2.5 0.27 11.0 1.7 1.6 1 0 0 1 1 1 0 Tom37 C-terminal domain Myc_N PF01056.13 XP_011271028.1 - 0.12 11.5 1.6 0.18 10.9 1.1 1.2 1 0 0 1 1 1 0 Myc amino-terminal region NmrA PF05368.8 XP_011271030.1 - 1.2e-10 41.0 0.0 2.1e-10 40.2 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 XP_011271030.1 - 0.00058 19.9 0.0 0.00074 19.5 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 XP_011271030.1 - 0.016 13.9 0.0 0.028 13.1 0.0 1.5 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 XP_011271030.1 - 0.018 14.0 0.0 0.024 13.6 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase DUF2577 PF10844.3 XP_011271030.1 - 0.073 13.1 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2577) DNA_primase_lrg PF04104.9 XP_011271031.1 - 1.1e-73 247.7 0.1 1.7e-73 247.0 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit KilA-N PF04383.8 XP_011271032.1 - 8e-05 22.2 3.8 0.00013 21.4 0.0 3.0 2 1 0 2 2 2 1 KilA-N domain DUF3528 PF12045.3 XP_011271033.1 - 0.0052 16.9 0.1 0.059 13.4 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3528) DUF4137 PF13593.1 XP_011271035.1 - 2.6e-99 332.2 19.8 3e-99 332.0 13.8 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.11 XP_011271035.1 - 1.6e-12 47.2 8.0 1.6e-12 47.2 5.5 2.5 2 1 1 3 3 3 1 Sodium Bile acid symporter family IER PF05760.7 XP_011271035.1 - 0.069 13.0 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Immediate early response protein (IER) MFS_1 PF07690.11 XP_011271036.1 - 2.2e-39 135.1 17.1 2.9e-39 134.7 11.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MgtC PF02308.11 XP_011271036.1 - 0.013 15.3 0.8 2.4 7.9 0.0 4.1 5 1 0 5 5 5 0 MgtC family FAM165 PF14981.1 XP_011271036.1 - 0.021 14.3 0.1 0.063 12.7 0.1 1.8 1 0 0 1 1 1 0 FAM165 family CD34_antigen PF06365.7 XP_011271036.1 - 0.084 12.5 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 CD34/Podocalyxin family NVEALA PF14055.1 XP_011271036.1 - 1.2 8.8 5.0 1.6 8.5 0.2 2.9 3 0 0 3 3 3 0 NVEALA protein Isochorismatase PF00857.15 XP_011271037.1 - 3.3e-38 131.3 0.2 3.6e-38 131.2 0.1 1.1 1 0 0 1 1 1 1 Isochorismatase family CoA_binding PF02629.14 XP_011271037.1 - 0.1 13.0 0.3 1.8 9.1 0.0 2.5 1 1 1 2 2 2 0 CoA binding domain AATase PF07247.7 XP_011271038.1 - 1.9e-27 95.9 17.9 8.2e-27 93.8 12.4 1.8 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 XP_011271038.1 - 7.4e-06 25.0 1.6 1.4e-05 24.1 1.1 1.3 1 0 0 1 1 1 1 Condensation domain Sugar_tr PF00083.19 XP_011271039.1 - 3.8e-100 335.6 27.6 4.7e-100 335.2 19.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 XP_011271039.1 - 2.2e-23 82.5 25.9 2.3e-21 75.9 11.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 XP_011271039.1 - 9.4e-05 20.9 2.1 9.4e-05 20.9 1.4 4.0 4 1 0 5 5 5 2 MFS/sugar transport protein AATase PF07247.7 XP_011271040.1 - 2.9e-58 197.6 16.6 3.3e-58 197.3 11.5 1.0 1 0 0 1 1 1 1 Alcohol acetyltransferase Mycoplasma_p37 PF06646.6 XP_011271040.1 - 0.0013 17.8 0.8 0.0026 16.8 0.6 1.6 1 1 0 1 1 1 1 High affinity transport system protein p37 Condensation PF00668.15 XP_011271040.1 - 0.019 13.8 0.2 0.035 12.9 0.2 1.4 1 0 0 1 1 1 0 Condensation domain Zip PF02535.17 XP_011271041.1 - 1.2e-26 93.4 0.0 1.4e-26 93.2 0.0 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter UNC-50 PF05216.8 XP_011271041.1 - 0.04 13.1 2.1 0.07 12.3 1.5 1.3 1 0 0 1 1 1 0 UNC-50 family DUF1514 PF07438.6 XP_011271041.1 - 0.054 13.4 0.1 0.093 12.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1514) DUF106 PF01956.11 XP_011271041.1 - 0.075 12.5 0.7 0.1 12.1 0.0 1.6 2 0 0 2 2 2 0 Integral membrane protein DUF106 Metallophos PF00149.23 XP_011271042.1 - 9.6e-43 145.9 0.7 1.3e-42 145.5 0.5 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF2268 PF10026.4 XP_011271042.1 - 0.12 11.7 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) CW_binding_1 PF01473.15 XP_011271042.1 - 0.41 10.8 2.4 1.1 9.4 1.7 1.8 1 0 0 1 1 1 0 Putative cell wall binding repeat Chorismate_bind PF00425.13 XP_011271043.1 - 4.8e-76 255.4 0.0 7.9e-75 251.4 0.0 2.1 2 0 0 2 2 2 1 chorismate binding enzyme GATase PF00117.23 XP_011271043.1 - 5.4e-37 127.1 0.0 9e-37 126.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 XP_011271043.1 - 2.6e-18 66.3 0.0 7.8e-18 64.8 0.0 1.8 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 XP_011271043.1 - 8e-10 38.5 0.0 2e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 Peptidase C26 PAT1 PF09770.4 XP_011271044.1 - 2.7e-185 617.9 82.7 1.9e-183 611.8 57.4 2.0 1 1 0 1 1 1 1 Topoisomerase II-associated protein PAT1 DUF3556 PF12077.3 XP_011271044.1 - 0.15 10.0 0.1 0.23 9.4 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein of unknown function (DUF3556) Zip PF02535.17 XP_011271044.1 - 1.2 8.1 10.0 1.9 7.3 7.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3007 PF11460.3 XP_011271044.1 - 4.5 7.3 7.0 13 5.9 4.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3007) AHS2 PF02626.10 XP_011271045.1 - 2.6e-64 217.1 0.0 4.2e-64 216.4 0.0 1.4 1 0 0 1 1 1 1 Allophanate hydrolase subunit 2 CPSase_L_D2 PF02786.12 XP_011271045.1 - 1.2e-57 194.5 0.0 2.3e-57 193.6 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 XP_011271045.1 - 7.1e-32 109.5 0.0 1.5e-31 108.5 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 XP_011271045.1 - 1.7e-28 98.8 0.1 3.9e-28 97.7 0.1 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain AHS1 PF02682.11 XP_011271045.1 - 4.6e-20 71.9 0.0 8.3e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 Allophanate hydrolase subunit 1 ATP-grasp_4 PF13535.1 XP_011271045.1 - 6e-14 52.1 0.0 1.1e-13 51.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 XP_011271045.1 - 6e-13 48.2 0.0 1.6e-08 33.7 0.0 2.1 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl PF00364.17 XP_011271045.1 - 4.8e-10 38.9 1.1 3e-08 33.1 0.2 3.1 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.8 XP_011271045.1 - 3.3e-09 36.4 0.0 7.4e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 XP_011271045.1 - 3.5e-06 26.4 0.0 6.1e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 XP_011271045.1 - 0.00069 19.1 0.0 0.0031 17.0 0.0 2.1 1 1 0 1 1 1 1 RimK-like ATP-grasp domain Biotin_lipoyl_2 PF13533.1 XP_011271045.1 - 0.003 17.1 0.7 0.083 12.5 0.1 2.7 2 0 0 2 2 2 1 Biotin-lipoyl like ATP-grasp_3 PF02655.9 XP_011271045.1 - 0.0059 16.4 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain DUF3182 PF11379.3 XP_011271045.1 - 0.15 10.7 0.0 0.46 9.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3182) SSF PF00474.12 XP_011271046.1 - 4.4e-17 61.8 19.9 4.4e-17 61.8 13.8 1.5 2 0 0 2 2 2 1 Sodium:solute symporter family DUF2207 PF09972.4 XP_011271046.1 - 0.0067 15.0 0.7 0.0067 15.0 0.5 3.3 4 0 0 4 4 4 1 Predicted membrane protein (DUF2207) Sugar_tr PF00083.19 XP_011271047.1 - 2.7e-121 405.3 22.4 3.5e-121 404.9 15.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 XP_011271047.1 - 4.5e-26 91.3 51.1 3.7e-22 78.5 16.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 XP_011271047.1 - 0.0019 16.5 2.2 0.0019 16.5 1.5 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Abi PF02517.11 XP_011271048.1 - 0.24 11.5 4.4 1.8 8.7 2.4 2.1 2 0 0 2 2 2 0 CAAX protease self-immunity SH3_1 PF00018.23 XP_011271049.1 - 6e-39 131.1 7.5 5.7e-14 51.2 0.2 4.2 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.1 XP_011271049.1 - 1e-33 114.6 9.5 1.9e-11 43.3 0.0 4.4 5 0 0 5 5 5 3 Variant SH3 domain SHD1 PF03983.7 XP_011271049.1 - 8.7e-32 108.6 0.1 1.7e-31 107.6 0.1 1.5 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_2 PF07653.12 XP_011271049.1 - 2.4e-29 100.5 0.1 1.3e-09 37.4 0.0 4.4 4 0 0 4 4 4 3 Variant SH3 domain SH3_3 PF08239.6 XP_011271049.1 - 0.053 13.7 3.4 0.28 11.4 0.0 3.1 3 0 0 3 3 3 0 Bacterial SH3 domain DASH_Duo1 PF08651.5 XP_011271050.1 - 2.4e-23 81.4 5.9 1.2e-22 79.2 1.4 2.7 3 0 0 3 3 3 1 DASH complex subunit Duo1 BRF1 PF07741.8 XP_011271050.1 - 0.014 15.6 7.6 0.014 15.6 5.2 1.8 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Sigma70_r1_1 PF03979.9 XP_011271050.1 - 0.066 13.1 0.6 0.46 10.4 0.0 2.2 2 0 0 2 2 2 0 Sigma-70 factor, region 1.1 DUF4391 PF14335.1 XP_011271050.1 - 0.1 12.0 12.7 0.13 11.5 8.8 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4391) HisKA PF00512.20 XP_011271050.1 - 0.15 12.1 0.1 0.15 12.1 0.1 2.1 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain DUF484 PF04340.7 XP_011271050.1 - 0.19 11.1 3.8 0.26 10.7 2.2 1.4 1 1 0 1 1 1 0 Protein of unknown function, DUF484 DASH_Dad2 PF08654.5 XP_011271050.1 - 0.4 10.6 8.2 0.57 10.2 3.6 2.5 2 1 0 2 2 2 0 DASH complex subunit Dad2 DUF1682 PF07946.9 XP_011271050.1 - 0.74 8.5 12.7 0.91 8.3 8.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF1664 PF07889.7 XP_011271050.1 - 1.1 9.0 3.9 10 5.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF3782 PF12644.2 XP_011271050.1 - 1.7 8.4 5.7 24 4.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3782) Elongin_A PF06881.6 XP_011271050.1 - 2.9 8.2 13.0 0.4 11.0 6.2 1.7 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Retrotrans_gag PF03732.12 XP_011271050.1 - 3.1 7.9 10.9 3.2 7.8 0.0 2.2 1 1 0 2 2 2 0 Retrotransposon gag protein OmpH PF03938.9 XP_011271050.1 - 4.5 7.2 13.0 6.5 6.6 7.1 2.0 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF3552 PF12072.3 XP_011271050.1 - 7.4 5.7 17.3 0.82 8.8 7.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) Aminotran_1_2 PF00155.16 XP_011271051.1 - 2.5e-19 69.4 0.0 3.3e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II WD40 PF00400.27 XP_011271052.1 - 1.2e-46 154.9 18.5 3.5e-09 36.1 0.1 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat Hira PF07569.6 XP_011271052.1 - 1.6e-14 53.6 0.3 8.9e-14 51.2 0.0 2.2 2 0 0 2 2 2 1 TUP1-like enhancer of split HIRA_B PF09453.5 XP_011271052.1 - 7.9e-09 34.8 0.2 2.1e-08 33.5 0.2 1.8 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.7 XP_011271052.1 - 0.033 13.8 1.4 32 4.3 0.0 4.5 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 XP_011271052.1 - 0.043 12.9 0.0 0.53 9.3 0.0 2.7 3 0 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal PBP1_TM PF14812.1 XP_011271052.1 - 0.83 10.0 5.7 2.7 8.3 3.9 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 XP_011271052.1 - 1.6 8.2 9.3 4.2 6.8 6.4 1.7 1 0 0 1 1 1 0 Nucleoplasmin zf-CCCH PF00642.19 XP_011271053.1 - 1.4e-08 34.1 3.4 1.4e-08 34.1 2.4 1.9 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_2 PF13923.1 XP_011271053.1 - 2.1e-07 30.8 16.5 3.8e-07 30.0 11.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 XP_011271053.1 - 8.8e-07 28.6 11.9 1.5e-06 27.9 8.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 XP_011271053.1 - 1.4e-06 27.8 12.0 2.4e-06 27.0 8.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 XP_011271053.1 - 2.8e-05 23.7 16.0 5.5e-05 22.8 11.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 XP_011271053.1 - 6.7e-05 22.5 7.1 0.00025 20.6 4.8 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.20 XP_011271053.1 - 0.00069 19.2 17.0 0.0013 18.3 11.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 XP_011271053.1 - 0.00091 19.0 13.9 0.0021 17.8 9.6 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 XP_011271053.1 - 0.053 13.0 8.2 0.099 12.1 5.7 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.2 XP_011271053.1 - 5.2 7.2 11.1 16 5.6 7.7 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger Pex24p PF06398.6 XP_011271054.1 - 1.1e-90 303.9 10.1 1.1e-90 303.9 7.0 2.0 2 1 0 2 2 2 1 Integral peroxisomal membrane peroxin Speriolin_N PF15058.1 XP_011271054.1 - 0.19 11.6 5.3 0.4 10.5 0.1 2.7 3 0 0 3 3 3 0 Speriolin N terminus Ribosomal_L38e PF01781.13 XP_011271055.1 - 1.4e-26 91.9 2.7 1.7e-26 91.7 1.8 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family Cadherin_pro PF08758.6 XP_011271055.1 - 0.066 12.9 0.1 0.071 12.8 0.0 1.1 1 0 0 1 1 1 0 Cadherin prodomain like TFIIF_beta PF02270.10 XP_011271056.1 - 4.9e-82 275.8 11.6 4.9e-82 275.8 8.0 1.7 2 0 0 2 2 2 1 Transcription initiation factor IIF, beta subunit Prp18 PF02840.10 XP_011271057.1 - 4.7e-40 136.7 0.2 4.7e-40 136.7 0.1 2.2 1 1 1 2 2 2 1 Prp18 domain DSPc PF00782.15 XP_011271058.1 - 1.2e-33 115.5 0.4 1.2e-33 115.5 0.2 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 XP_011271058.1 - 0.00095 18.5 1.1 0.0012 18.2 0.0 1.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase CDKN3 PF05706.7 XP_011271058.1 - 0.038 13.4 0.1 0.081 12.3 0.0 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) PAP2 PF01569.16 XP_011271059.1 - 7e-23 80.7 0.6 1.5e-22 79.6 0.4 1.4 1 0 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.1 XP_011271059.1 - 0.12 12.6 0.3 0.12 12.6 0.2 1.7 2 0 0 2 2 2 0 PAP2 superfamily C-terminal DUF2628 PF10947.3 XP_011271059.1 - 7.8 6.3 6.2 12 5.6 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2628) HGTP_anticodon2 PF12745.2 XP_011271060.1 - 1.7e-77 260.2 7.7 1.7e-77 260.2 5.3 3.2 4 0 0 4 4 4 1 Anticodon binding domain of tRNAs Pkinase PF00069.20 XP_011271060.1 - 6.2e-72 241.8 4.0 1.8e-44 151.8 0.1 4.6 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011271060.1 - 2.7e-44 151.1 0.6 2.3e-20 72.7 0.0 3.7 4 0 0 4 4 4 3 Protein tyrosine kinase RWD PF05773.17 XP_011271060.1 - 3.2e-21 75.3 3.1 8.7e-21 73.9 1.0 2.7 2 0 0 2 2 2 1 RWD domain tRNA-synt_His PF13393.1 XP_011271060.1 - 3.3e-14 52.6 0.1 1.3e-13 50.7 0.0 1.9 2 0 0 2 2 2 1 Histidyl-tRNA synthetase Kinase-like PF14531.1 XP_011271060.1 - 1.2e-06 27.7 0.1 0.00072 18.6 0.0 3.3 2 1 0 2 2 2 2 Kinase-like TraH_2 PF06871.6 XP_011271060.1 - 0.13 11.7 1.1 0.4 10.0 0.7 1.8 1 0 0 1 1 1 0 TraH_2 Trypan_PARP PF05887.6 XP_011271060.1 - 0.17 11.7 13.8 0.41 10.4 9.5 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) APH PF01636.18 XP_011271060.1 - 0.24 11.1 0.0 0.45 10.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family SH3_9 PF14604.1 XP_011271061.1 - 9.6e-09 34.6 0.1 3.2e-08 33.0 0.0 2.0 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 XP_011271061.1 - 1.5e-08 33.8 0.6 5.1e-08 32.1 0.1 2.2 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 XP_011271061.1 - 1.2e-06 27.8 0.0 4.9e-06 25.9 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SLS PF14611.1 XP_011271062.1 - 2.5e-25 89.1 2.5 5.5e-25 88.0 1.7 1.6 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator AnfG_VnfG PF03139.10 XP_011271062.1 - 0.038 13.7 0.1 1.3 8.7 0.0 2.8 3 0 0 3 3 3 0 Vanadium/alternative nitrogenase delta subunit PseudoU_synth_2 PF00849.17 XP_011271064.1 - 1.2e-27 96.7 0.1 2.3e-27 95.8 0.1 1.5 1 0 0 1 1 1 1 RNA pseudouridylate synthase DUF1014 PF06244.7 XP_011271068.1 - 5.6e-27 94.3 19.6 1e-25 90.3 13.6 2.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1014) Arteri_nucleo PF01481.11 XP_011271068.1 - 1.2 9.2 7.8 7.9 6.5 2.2 2.2 2 0 0 2 2 2 0 Arterivirus nucleocapsid protein HTH_32 PF13565.1 XP_011271068.1 - 6 7.7 6.8 1.3 9.8 0.1 2.7 3 1 0 3 3 3 0 Homeodomain-like domain RVT_2 PF07727.9 XP_011271070.1 - 2e-75 252.9 0.0 2.9e-75 252.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 XP_011271070.1 - 2.4e-20 72.8 0.0 4.6e-20 71.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain zf-CCHC PF00098.18 XP_011271070.1 - 1.9e-06 27.5 3.2 3.6e-06 26.6 2.2 1.5 1 0 0 1 1 1 1 Zinc knuckle gag_pre-integrs PF13976.1 XP_011271070.1 - 4.8e-05 22.9 0.0 0.00012 21.6 0.0 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 XP_011271070.1 - 0.12 11.8 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain Nanovirus_C8 PF05629.6 XP_011271071.1 - 0.51 10.1 7.4 0.5 10.1 0.7 3.0 2 1 0 3 3 3 0 Nanovirus component 8 (C8) protein RVT_2 PF07727.9 XP_011271072.1 - 4.3e-61 206.0 0.2 7.5e-61 205.2 0.2 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 XP_011271072.1 - 1.6e-26 92.7 0.0 4.5e-26 91.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 XP_011271072.1 - 1.1e-07 31.3 2.5 1.8e-07 30.7 0.0 2.8 3 0 0 3 3 3 1 GAG-pre-integrase domain rve_3 PF13683.1 XP_011271072.1 - 0.036 13.5 0.1 0.21 11.1 0.0 2.4 2 0 0 2 2 2 0 Integrase core domain zf-CCHC PF00098.18 XP_011271072.1 - 0.036 13.9 1.7 0.082 12.8 1.2 1.6 1 0 0 1 1 1 0 Zinc knuckle Nucleoplasmin PF03066.10 XP_011271074.1 - 0.15 11.5 3.5 0.26 10.7 2.4 1.4 1 0 0 1 1 1 0 Nucleoplasmin His_Phos_2 PF00328.17 XP_011271075.1 - 1.1e-40 140.0 0.0 1.4e-40 139.7 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) HTH_3 PF01381.17 XP_011271075.1 - 0.03 14.1 0.0 7 6.5 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix PI31_Prot_C PF08577.6 XP_011271078.1 - 1.2e-07 32.2 13.9 3.8e-07 30.6 9.6 1.9 1 0 0 1 1 1 1 PI31 proteasome regulator Glucosamine_iso PF01182.15 XP_011271079.1 - 9.6e-49 165.8 0.0 1.5e-48 165.2 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase zf-BED PF02892.10 XP_011271080.1 - 0.0019 17.9 1.3 0.0036 17.0 0.9 1.4 1 0 0 1 1 1 1 BED zinc finger DUF1059 PF06348.6 XP_011271080.1 - 0.016 14.9 0.6 0.043 13.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1059) Xpo1 PF08389.7 XP_011271080.1 - 0.076 12.9 0.7 0.13 12.1 0.5 1.3 1 0 0 1 1 1 0 Exportin 1-like protein SurA_N_2 PF13623.1 XP_011271080.1 - 1.6 8.6 6.9 0.39 10.6 2.6 1.5 2 0 0 2 2 2 0 SurA N-terminal domain AATase PF07247.7 XP_011271081.1 - 1.3e-05 24.0 5.9 4.3e-05 22.2 0.4 2.3 1 1 1 2 2 2 2 Alcohol acetyltransferase Y_phosphatase PF00102.22 XP_011271083.1 - 1.8e-56 191.1 1.6 2.2e-56 190.8 1.1 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 XP_011271083.1 - 0.00032 20.3 0.1 0.0013 18.3 0.0 2.1 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 XP_011271083.1 - 0.00069 19.6 0.0 0.012 15.7 0.0 2.3 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 XP_011271083.1 - 0.0033 17.6 0.0 0.01 16.0 0.0 1.8 2 0 0 2 2 2 1 Tyrosine phosphatase family PP2C PF00481.16 XP_011271084.1 - 2.7e-31 108.8 0.1 7.9e-20 71.3 0.0 3.1 2 1 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.7 XP_011271084.1 - 5e-05 23.0 0.0 0.00011 21.9 0.0 1.5 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 XP_011271084.1 - 0.023 14.1 0.0 0.053 12.9 0.0 1.5 1 1 0 1 1 1 0 Protein phosphatase 2C Ribosomal_S19 PF00203.16 XP_011271085.1 - 4.7e-22 77.3 0.0 5.8e-22 77.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 DEAD PF00270.24 XP_011271086.1 - 4.9e-37 127.0 0.1 2e-36 125.0 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 XP_011271086.1 - 3.1e-21 75.0 0.4 1.5e-20 72.7 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 XP_011271086.1 - 2.3e-06 27.5 0.0 2.3e-06 27.5 0.0 3.1 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 XP_011271086.1 - 0.044 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain Helicase_C_2 PF13307.1 XP_011271086.1 - 0.051 13.5 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 Helicase C-terminal domain UvrD-helicase PF00580.16 XP_011271086.1 - 0.057 12.7 0.0 0.057 12.7 0.0 3.0 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain PP-binding PF00550.20 XP_011271087.1 - 1.7e-11 44.2 0.7 2.5e-11 43.6 0.5 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site DUF1493 PF07377.7 XP_011271087.1 - 0.00098 19.2 0.5 0.0015 18.6 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1493) PP-binding_2 PF14573.1 XP_011271087.1 - 0.082 12.9 0.8 0.24 11.4 0.5 1.7 1 1 0 1 1 1 0 Acyl-carrier Ribosom_S12_S23 PF00164.20 XP_011271088.1 - 5.2e-44 148.5 2.0 7e-44 148.1 1.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 P34-Arc PF04045.9 XP_011271089.1 - 7.6e-104 346.2 3.0 1.2e-103 345.6 2.1 1.3 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc ARPC4 PF05856.7 XP_011271089.1 - 0.031 13.6 3.5 0.062 12.6 2.4 1.5 1 1 0 1 1 1 0 ARP2/3 complex 20 kDa subunit (ARPC4) LamB_YcsF PF03746.11 XP_011271090.1 - 3.8e-66 222.6 0.0 4.4e-66 222.4 0.0 1.0 1 0 0 1 1 1 1 LamB/YcsF family AAA_18 PF13238.1 XP_011271091.1 - 8.9e-07 29.2 0.7 9.7e-06 25.9 0.5 2.0 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 XP_011271091.1 - 7.3e-06 26.8 0.4 1.8e-05 25.5 0.3 1.7 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 XP_011271091.1 - 3.6e-05 23.3 0.0 4.2e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.7 XP_011271091.1 - 7.2e-05 21.9 0.0 0.00018 20.6 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.1 XP_011271091.1 - 0.0025 17.6 0.0 0.0071 16.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.5 XP_011271091.1 - 0.0041 16.3 0.0 0.0061 15.8 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 cobW PF02492.14 XP_011271091.1 - 0.0054 16.1 0.0 0.0092 15.4 0.0 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 XP_011271091.1 - 0.012 15.6 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.17 XP_011271091.1 - 0.017 15.3 0.0 0.061 13.4 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA_5 PF07728.9 XP_011271091.1 - 0.019 14.6 0.0 0.039 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 XP_011271091.1 - 0.022 15.0 0.2 0.033 14.4 0.1 1.7 1 1 0 1 1 1 0 ABC transporter AAA_19 PF13245.1 XP_011271091.1 - 0.025 14.3 0.0 0.048 13.4 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_28 PF13521.1 XP_011271091.1 - 0.026 14.4 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 XP_011271091.1 - 0.048 12.4 0.0 0.07 11.8 0.0 1.2 1 0 0 1 1 1 0 ArgK protein FtsK_SpoIIIE PF01580.13 XP_011271091.1 - 0.05 13.0 0.0 0.07 12.6 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family NTPase_1 PF03266.10 XP_011271091.1 - 0.06 13.0 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 NTPase DUF2075 PF09848.4 XP_011271091.1 - 0.061 12.2 0.0 0.1 11.5 0.0 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.16 XP_011271091.1 - 0.068 12.3 0.0 0.39 9.8 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA PF00004.24 XP_011271091.1 - 0.072 13.2 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DNA_pol3_a_NII PF11490.3 XP_011271091.1 - 0.081 12.5 0.2 12 5.5 0.0 2.3 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II Viral_helicase1 PF01443.13 XP_011271091.1 - 0.09 12.2 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_10 PF12846.2 XP_011271091.1 - 0.093 12.1 0.0 0.17 11.2 0.0 1.4 1 1 0 1 1 1 0 AAA-like domain T2SE PF00437.15 XP_011271091.1 - 0.099 11.5 0.0 0.25 10.2 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein MMR_HSR1 PF01926.18 XP_011271091.1 - 0.13 12.2 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.1 XP_011271091.1 - 0.13 12.4 0.0 0.3 11.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.4 XP_011271091.1 - 0.13 10.8 0.0 0.17 10.4 0.0 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.7 XP_011271091.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.1 XP_011271091.1 - 0.19 11.3 0.3 0.39 10.2 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain OB_NTP_bind PF07717.11 XP_011271092.1 - 1.1e-17 63.8 0.0 3.5e-17 62.2 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 XP_011271092.1 - 8e-13 48.2 0.0 2.8e-12 46.5 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) DEAD PF00270.24 XP_011271092.1 - 3.1e-12 46.3 0.6 1.5e-11 44.0 0.1 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 XP_011271092.1 - 3.3e-11 42.8 0.0 8.6e-11 41.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RWD PF05773.17 XP_011271092.1 - 1.1e-09 38.2 0.5 4.5e-09 36.2 0.3 2.2 1 0 0 1 1 1 1 RWD domain AAA_22 PF13401.1 XP_011271092.1 - 7e-05 22.9 0.1 0.00023 21.2 0.1 1.9 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 XP_011271092.1 - 0.00092 18.6 0.0 0.0026 17.2 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SE PF00437.15 XP_011271092.1 - 0.004 16.1 0.1 0.0075 15.1 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Zot PF05707.7 XP_011271092.1 - 0.0085 15.5 0.0 0.032 13.7 0.0 2.0 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_19 PF13245.1 XP_011271092.1 - 0.021 14.5 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain FtsK_SpoIIIE PF01580.13 XP_011271092.1 - 0.087 12.2 0.0 0.2 11.0 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_30 PF13604.1 XP_011271092.1 - 0.15 11.6 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 XP_011271092.1 - 0.15 11.4 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zn_clus PF00172.13 XP_011271093.1 - 8.1e-07 28.8 17.1 8.1e-07 28.8 11.8 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2439 PF10382.4 XP_011271093.1 - 1.9 8.7 5.1 0.59 10.3 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2439) GSHPx PF00255.14 XP_011271094.1 - 7.2e-48 160.4 0.5 9.3e-48 160.0 0.4 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 XP_011271094.1 - 1.9e-06 27.6 0.2 8.4e-06 25.4 0.1 1.9 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 XP_011271094.1 - 0.00024 20.6 0.1 0.00068 19.2 0.1 1.8 1 1 0 1 1 1 1 Redoxin DUF4174 PF13778.1 XP_011271094.1 - 0.012 15.7 0.0 0.022 14.8 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4174) GTP_cyclohydro2 PF00925.15 XP_011271095.1 - 8.3e-60 200.8 0.1 5.4e-54 181.9 0.0 2.1 1 1 1 2 2 2 2 GTP cyclohydrolase II Thioredoxin PF00085.15 XP_011271096.1 - 0.00035 20.2 0.0 0.0005 19.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 XP_011271096.1 - 0.0067 16.6 0.0 0.02 15.0 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Glutaredoxin PF00462.19 XP_011271096.1 - 0.058 13.3 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin Thioredoxin_3 PF13192.1 XP_011271096.1 - 0.09 12.6 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin domain WD40 PF00400.27 XP_011271097.1 - 6.9e-11 41.6 6.8 9.9e-07 28.4 0.1 5.1 5 1 0 5 5 5 2 WD domain, G-beta repeat eIF2A PF08662.6 XP_011271097.1 - 9.2e-05 22.2 0.0 0.17 11.5 0.0 2.3 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A CPSF_A PF03178.10 XP_011271097.1 - 0.0026 16.9 0.0 0.0052 15.9 0.0 1.5 1 1 0 1 1 1 1 CPSF A subunit region PD40 PF07676.7 XP_011271097.1 - 0.05 13.2 0.5 0.13 11.9 0.0 1.9 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat EF-hand_7 PF13499.1 XP_011271098.1 - 3.9e-16 58.9 0.0 9.9e-11 41.6 0.0 2.1 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 XP_011271098.1 - 3.2e-13 47.9 0.3 0.00047 19.2 0.0 3.4 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 XP_011271098.1 - 4.3e-13 47.9 0.3 0.00014 21.4 0.0 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 XP_011271098.1 - 8.8e-10 38.0 0.3 3.6e-07 29.7 0.1 2.8 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_9 PF14658.1 XP_011271098.1 - 4.9e-08 32.7 0.0 0.0011 18.7 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 XP_011271098.1 - 1.1e-05 24.4 0.1 0.016 14.5 0.0 3.0 3 0 0 3 3 3 2 EF hand UPF0154 PF03672.8 XP_011271098.1 - 0.018 14.6 0.0 0.091 12.3 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 XP_011271098.1 - 0.029 14.3 0.0 1.1 9.3 0.0 2.6 2 1 0 2 2 2 0 Ca2+ insensitive EF hand EF-hand_4 PF12763.2 XP_011271098.1 - 0.12 12.1 0.0 4.1 7.2 0.0 2.1 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand PAS PF00989.19 XP_011271099.1 - 8.4e-08 31.9 0.2 4.4e-07 29.6 0.0 2.2 2 1 1 3 3 3 1 PAS fold Zn_clus PF00172.13 XP_011271099.1 - 0.0029 17.4 4.4 0.0053 16.6 3.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAT1 PF09770.4 XP_011271099.1 - 3.8 5.6 33.5 5.1 5.2 23.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 tRNA_bind PF01588.15 XP_011271100.1 - 2.3e-27 94.6 0.0 4.1e-27 93.8 0.0 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C_3 PF14497.1 XP_011271100.1 - 4.7e-07 30.2 0.6 5.1e-06 26.8 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 XP_011271100.1 - 0.00084 19.1 0.0 0.0019 18.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain UPF0560 PF10577.4 XP_011271100.1 - 0.079 11.2 4.4 0.13 10.5 3.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Cwf_Cwc_15 PF04889.7 XP_011271100.1 - 0.082 12.6 13.9 0.14 11.8 9.6 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NAM-associated PF14303.1 XP_011271100.1 - 0.091 13.0 16.6 0.16 12.2 11.5 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain GST_C PF00043.20 XP_011271100.1 - 0.19 11.7 1.2 0.6 10.1 0.0 2.3 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain SR-25 PF10500.4 XP_011271100.1 - 0.39 10.1 18.6 0.18 11.2 11.2 1.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Tom37_C PF11801.3 XP_011271100.1 - 1.8 8.4 9.4 1.6 8.5 0.1 2.4 2 0 0 2 2 2 0 Tom37 C-terminal domain Med19 PF10278.4 XP_011271100.1 - 4.5 6.9 19.5 7.5 6.1 13.5 1.3 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 eRF1_1 PF03463.10 XP_011271101.1 - 2.8e-34 117.5 1.2 2.8e-34 117.5 0.8 1.7 2 0 0 2 2 2 1 eRF1 domain 1 eRF1_2 PF03464.10 XP_011271101.1 - 4.4e-28 98.2 0.2 7.7e-28 97.4 0.2 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 XP_011271101.1 - 4.3e-24 84.9 0.0 1.7e-23 82.9 0.0 2.0 2 0 0 2 2 2 1 eRF1 domain 3 Tim17 PF02466.14 XP_011271102.1 - 0.0005 20.1 1.3 0.0014 18.6 0.9 1.9 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Sugar_tr PF00083.19 XP_011271103.1 - 1.2e-93 314.1 11.8 2.3e-93 313.2 8.2 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 XP_011271103.1 - 1.9e-30 105.7 30.2 1.2e-22 80.1 4.3 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 XP_011271103.1 - 1.9e-07 29.7 7.9 1.2e-06 27.0 1.1 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Ribosomal_L18e PF00828.14 XP_011271104.1 - 8.7e-32 110.2 0.2 1.2e-31 109.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 RTC4 PF14474.1 XP_011271104.1 - 0.16 11.9 0.1 0.3 11.0 0.1 1.5 1 1 0 1 1 1 0 RTC4-like domain HD_3 PF13023.1 XP_011271105.1 - 1.3e-38 132.3 0.1 1.6e-38 132.0 0.0 1.1 1 0 0 1 1 1 1 HD domain HD PF01966.17 XP_011271105.1 - 0.00026 20.9 0.0 0.00051 20.0 0.0 1.5 1 0 0 1 1 1 1 HD domain Glycos_transf_4 PF00953.16 XP_011271106.1 - 5.1e-33 114.1 11.6 5.1e-33 114.1 8.0 2.4 3 1 0 3 3 3 1 Glycosyl transferase family 4 SapA PF02199.10 XP_011271110.1 - 0.092 12.5 0.9 0.092 12.5 0.6 2.0 2 0 0 2 2 2 0 Saposin A-type domain DUF4485 PF14846.1 XP_011271111.1 - 0.026 14.2 0.1 0.042 13.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4485) DUF3079 PF11278.3 XP_011271118.1 - 0.85 9.2 3.8 0.62 9.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3079) zf-RVT PF13966.1 XP_011271121.1 - 1e-05 25.7 1.5 1e-05 25.7 1.0 1.9 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase Symplekin_C PF12295.3 XP_011271121.1 - 0.047 13.6 0.1 0.086 12.7 0.1 1.4 1 0 0 1 1 1 0 Symplekin tight junction protein C terminal MFS_1 PF07690.11 XP_011271123.1 - 3.4e-18 65.4 15.6 4.7e-18 65.0 10.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily LRR_4 PF12799.2 XP_011271123.1 - 0.11 12.2 10.7 1.5 8.5 0.4 5.0 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) Peptidase_M3 PF01432.15 XP_011271124.1 - 1.1e-144 482.9 0.9 1.1e-144 482.9 0.6 1.7 2 0 0 2 2 2 1 Peptidase family M3 DUF3106 PF11304.3 XP_011271124.1 - 0.028 14.8 0.3 0.076 13.4 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3106) DUF1002 PF06207.6 XP_011271124.1 - 4.2 6.6 5.1 1.6 7.9 1.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1002) DUF543 PF04418.7 XP_011271125.1 - 7.5e-30 102.7 0.1 8.4e-30 102.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF543) NADH_dh_m_C1 PF15088.1 XP_011271125.1 - 0.54 9.7 3.9 5.7 6.5 0.2 2.2 1 1 1 2 2 2 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial zf-C2H2_6 PF13912.1 XP_011271127.1 - 0.00026 20.7 7.3 0.014 15.2 0.2 3.7 3 1 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 XP_011271127.1 - 0.0013 18.9 0.9 0.0013 18.9 0.7 5.0 5 0 0 5 5 5 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 XP_011271127.1 - 0.0018 18.4 21.3 0.008 16.4 0.2 4.6 3 1 1 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 XP_011271127.1 - 0.052 13.8 21.2 0.45 10.9 0.5 5.0 4 2 0 4 4 4 0 C2H2-type zinc finger zf-RING_3 PF14369.1 XP_011271127.1 - 0.084 12.8 0.5 5.4 7.0 0.0 2.8 2 0 0 2 2 2 0 zinc-finger DZR PF12773.2 XP_011271127.1 - 0.086 12.6 3.0 0.54 10.1 0.3 2.5 2 0 0 2 2 2 0 Double zinc ribbon zf-C2HC_2 PF13913.1 XP_011271127.1 - 0.098 12.3 3.4 0.87 9.3 0.4 3.1 2 0 0 2 2 2 0 zinc-finger of a C2HC-type DUF2321 PF10083.4 XP_011271127.1 - 0.29 10.6 2.4 5.3 6.5 0.2 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) zf-C2H2_jaz PF12171.3 XP_011271127.1 - 1 9.5 9.0 2.1 8.6 0.1 3.9 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.5 XP_011271127.1 - 3.2 7.7 7.7 17 5.4 0.2 3.4 3 0 0 3 3 3 0 Zinc ribbon domain Cytochrome_C7 PF14522.1 XP_011271127.1 - 3.6 7.2 10.7 0.49 10.0 1.0 2.7 2 1 0 2 2 2 0 Cytochrome c7 ELO PF01151.13 XP_011271128.1 - 1.2e-57 195.1 24.9 1.4e-57 194.8 17.2 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family CNH PF00780.17 XP_011271129.1 - 5.7e-80 268.6 0.1 1.3e-79 267.5 0.0 1.6 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.1 XP_011271129.1 - 7.4e-36 123.0 0.1 7.4e-36 123.0 0.1 3.1 3 1 1 4 4 4 1 Pleckstrin homology domain RhoGEF PF00621.15 XP_011271129.1 - 2.2e-34 118.8 1.0 4.5e-34 117.8 0.7 1.6 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.16 XP_011271129.1 - 1.4e-13 50.3 0.0 2.9e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FAD_binding_8 PF08022.7 XP_011271130.1 - 1.9e-20 72.7 0.1 3.5e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 XP_011271130.1 - 8.8e-20 71.1 0.0 1.2e-18 67.5 0.0 2.1 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 XP_011271130.1 - 1.8e-18 66.8 14.4 1.1e-17 64.3 8.2 2.6 2 0 0 2 2 2 1 Ferric reductase like transmembrane component Retrotrans_gag PF03732.12 XP_011271131.1 - 4.4e-12 45.9 0.0 4.4e-12 45.9 0.0 2.6 3 0 0 3 3 3 1 Retrotransposon gag protein Asp_protease_2 PF13650.1 XP_011271131.1 - 3.4e-06 27.4 0.6 1.2e-05 25.7 0.1 2.3 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 XP_011271131.1 - 0.00049 19.8 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease MCPsignal PF00015.16 XP_011271131.1 - 0.005 16.4 2.9 0.013 15.1 2.0 1.6 1 0 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain RVP PF00077.15 XP_011271131.1 - 0.024 14.5 0.0 0.09 12.7 0.0 2.0 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF866 PF05907.8 XP_011271132.1 - 3.3e-21 75.4 2.4 3.4e-11 42.9 0.0 2.0 1 1 1 2 2 2 2 Eukaryotic protein of unknown function (DUF866) Flocculin_t3 PF13928.1 XP_011271133.1 - 1.6e-40 136.9 187.8 4.4e-13 49.1 10.5 12.6 11 1 1 12 12 12 9 Flocculin type 3 repeat Pkinase PF00069.20 XP_011271134.1 - 3.3e-73 246.0 0.2 6.6e-73 245.0 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011271134.1 - 8.5e-32 110.2 0.1 2.8e-31 108.5 0.1 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 XP_011271134.1 - 4.8e-08 32.3 0.4 1.8e-05 23.8 0.0 2.9 1 1 1 2 2 2 2 Kinase-like Kdo PF06293.9 XP_011271134.1 - 0.052 12.5 0.0 0.094 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MutS_V PF00488.16 XP_011271135.1 - 5.9e-79 264.7 0.1 1.2e-78 263.7 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 XP_011271135.1 - 1.4e-39 135.9 1.1 1.4e-39 135.9 0.7 2.1 3 0 0 3 3 3 1 MutS domain III MutS_I PF01624.15 XP_011271135.1 - 1.9e-25 89.0 0.1 6.5e-25 87.3 0.0 1.9 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.12 XP_011271135.1 - 8.2e-11 42.1 2.2 3e-10 40.2 0.6 2.7 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 XP_011271135.1 - 1.2e-05 25.3 1.8 2.6e-05 24.3 0.1 2.6 2 0 0 2 2 2 1 MutS family domain IV AAA_16 PF13191.1 XP_011271135.1 - 0.092 12.7 0.0 1.2 9.0 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain Pkinase PF00069.20 XP_011271136.1 - 1.9e-38 132.0 2.1 1.9e-20 73.0 0.3 2.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011271136.1 - 2e-12 46.7 0.1 1.1e-08 34.4 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Actin PF00022.14 XP_011271137.1 - 1.5e-150 501.0 0.0 1.7e-150 500.8 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 XP_011271137.1 - 0.066 13.6 0.0 0.17 12.2 0.0 1.7 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) WHIM1 PF15612.1 XP_011271138.1 - 0.0096 15.8 0.1 0.026 14.4 0.1 1.8 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Pro_isomerase PF00160.16 XP_011271139.1 - 2e-25 89.8 1.0 3.2e-25 89.1 0.1 1.8 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD NAD_binding_10 PF13460.1 XP_011271140.1 - 2.7e-15 56.8 0.0 4e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 XP_011271140.1 - 5.7e-13 48.6 0.0 8e-13 48.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 XP_011271140.1 - 1.5e-12 46.8 0.0 2.9e-12 45.8 0.0 1.5 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 XP_011271140.1 - 2.3e-12 46.8 0.1 6.9e-12 45.2 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 XP_011271140.1 - 3.2e-10 39.3 0.0 7.2e-09 34.9 0.0 2.2 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 XP_011271140.1 - 0.00036 19.5 0.7 0.4 9.5 0.0 2.3 1 1 1 2 2 2 2 Male sterility protein Saccharop_dh PF03435.13 XP_011271140.1 - 0.005 15.8 0.0 0.0086 15.0 0.0 1.4 1 1 0 1 1 1 1 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 XP_011271140.1 - 0.06 12.2 0.0 0.099 11.5 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein TatD_DNase PF01026.16 XP_011271140.1 - 0.1 11.8 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 TatD related DNase CPSase_L_D2 PF02786.12 XP_011271141.1 - 0.00016 21.0 0.0 0.00019 20.8 0.0 1.1 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.17 XP_011271141.1 - 0.018 14.4 0.0 0.021 14.1 0.0 1.1 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp_4 PF13535.1 XP_011271141.1 - 0.13 11.9 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 ATP-grasp domain DUF1676 PF07898.8 XP_011271142.1 - 0.037 14.3 1.1 0.052 13.8 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) CUE PF02845.11 XP_011271143.1 - 1.3e-09 37.3 0.0 2.5e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 CUE domain Transposase_21 PF02992.9 XP_011271145.1 - 7.6e-13 48.0 0.2 2.1e-12 46.6 0.1 1.7 1 0 0 1 1 1 1 Transposase family tnp2 CPSase_L_D3 PF02787.14 XP_011271146.1 - 8.1e-06 25.6 0.0 1.6e-05 24.6 0.0 1.5 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain TetR_C_5 PF08360.6 XP_011271147.1 - 0.11 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 QacR-like protein, C-terminal region Vma12 PF11712.3 XP_011271148.1 - 1.5 8.5 5.2 0.86 9.2 1.8 1.9 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase CPSase_L_D3 PF02787.14 XP_011271149.1 - 0.11 12.3 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain PUB PF09409.5 XP_011271150.1 - 0.0032 17.1 2.2 0.0035 17.0 0.4 1.8 2 0 0 2 2 2 1 PUB domain PAS_10 PF13596.1 XP_011271150.1 - 0.025 14.8 0.1 0.054 13.7 0.1 1.6 1 0 0 1 1 1 0 PAS domain Fes1 PF08609.5 XP_011271151.1 - 0.17 12.3 16.1 5.8 7.4 0.3 4.2 2 1 2 4 4 4 0 Nucleotide exchange factor Fes1 F-box PF00646.28 XP_011271152.1 - 0.0021 17.6 0.0 0.0052 16.3 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 XP_011271152.1 - 0.0081 15.8 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 F-box-like Fip1 PF05182.8 XP_011271153.1 - 0.097 11.9 0.0 0.19 10.9 0.0 1.5 1 0 0 1 1 1 0 Fip1 motif Methyltransf_16 PF10294.4 XP_011271154.1 - 3e-20 72.3 0.2 4.5e-20 71.8 0.1 1.2 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 XP_011271154.1 - 0.0017 17.7 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 XP_011271154.1 - 0.019 14.1 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.1 XP_011271154.1 - 0.048 13.3 0.0 0.072 12.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 XP_011271154.1 - 0.053 12.5 0.0 0.49 9.3 0.0 2.2 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase Methyltransf_18 PF12847.2 XP_011271154.1 - 0.1 13.2 0.0 0.18 12.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain CBFB_NFYA PF02045.10 XP_011271155.1 - 0.62 10.6 3.7 31 5.2 0.0 3.4 3 0 0 3 3 3 0 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B DUF1268 PF06896.6 XP_011271156.1 - 0.042 14.1 0.2 0.052 13.8 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1268) zf-H2C2_2 PF13465.1 XP_011271157.1 - 5.3e-06 26.4 3.7 5.3e-06 26.4 2.5 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 XP_011271157.1 - 2.9e-05 24.1 19.6 0.0035 17.6 2.5 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 XP_011271157.1 - 0.015 15.6 13.6 0.24 11.8 2.8 3.1 2 0 0 2 2 2 0 C2H2-type zinc finger Dus PF01207.12 XP_011271158.1 - 3.9e-80 268.9 0.0 5.2e-80 268.5 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Peptidase_M28 PF04389.12 XP_011271159.1 - 2.3e-16 60.0 0.0 4.7e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.10 XP_011271159.1 - 3.9e-13 49.0 0.0 1e-12 47.7 0.0 1.6 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.17 XP_011271159.1 - 1.3e-05 24.7 0.1 3.3e-05 23.5 0.1 1.6 1 0 0 1 1 1 1 PA domain Pro_isomerase PF00160.16 XP_011271160.1 - 3.9e-34 118.0 0.1 4.5e-34 117.9 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ENTH PF01417.15 XP_011271161.1 - 1.7e-46 157.1 0.1 2.9e-46 156.3 0.1 1.4 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 XP_011271161.1 - 9.2e-06 24.5 0.0 1.4e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 ANTH domain DSS1_SEM1 PF05160.8 XP_011271161.1 - 0.025 14.3 0.9 0.65 9.8 0.0 2.9 3 0 0 3 3 3 0 DSS1/SEM1 family VHS PF00790.14 XP_011271161.1 - 0.038 13.6 0.0 0.091 12.3 0.0 1.5 1 1 0 1 1 1 0 VHS domain FUSC_2 PF13515.1 XP_011271162.1 - 6.7e-29 100.3 14.5 1.4e-28 99.3 4.3 2.5 2 0 0 2 2 2 2 Fusaric acid resistance protein-like FUSC PF04632.7 XP_011271162.1 - 3e-07 29.2 0.0 3.9e-06 25.6 0.1 2.3 2 0 0 2 2 2 1 Fusaric acid resistance protein family ALMT PF11744.3 XP_011271162.1 - 3.7e-05 22.5 5.2 3.7e-05 22.5 3.6 3.3 3 1 1 4 4 4 3 Aluminium activated malate transporter DUF2421 PF10334.4 XP_011271162.1 - 0.0006 19.4 1.6 0.016 14.8 0.3 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF2421) Nab2 PF11517.3 XP_011271163.1 - 8.4e-15 54.7 0.2 1.8e-14 53.7 0.1 1.6 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) zf-CCCH_2 PF14608.1 XP_011271163.1 - 3.4e-07 30.0 75.3 0.0079 16.1 2.4 7.8 7 2 0 7 7 7 5 Zinc finger C-x8-C-x5-C-x3-H type DUF2508 PF10704.4 XP_011271163.1 - 0.05 13.7 0.2 0.13 12.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2508) Ribosomal_S5 PF00333.15 XP_011271164.1 - 1.6e-29 101.3 2.2 4.3e-29 100.0 1.5 1.8 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 XP_011271164.1 - 6e-22 76.7 0.1 1.1e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain DUF3829 PF12889.2 XP_011271165.1 - 0.026 13.7 0.9 0.035 13.3 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) Arrestin_N PF00339.24 XP_011271166.1 - 1e-11 44.8 0.2 3e-11 43.3 0.1 1.8 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_N PF00339.24 XP_011271167.1 - 2.6e-11 43.5 1.2 6e-11 42.3 0.1 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_N PF00339.24 XP_011271168.1 - 1.5e-11 44.3 0.0 6.3e-11 42.3 0.0 2.0 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_N PF00339.24 XP_011271169.1 - 2.1e-11 43.8 0.0 9.1e-11 41.7 0.0 2.1 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain AAA_4 PF04326.9 XP_011271169.1 - 0.018 15.2 1.6 0.09 12.9 0.8 2.2 2 0 0 2 2 2 0 Divergent AAA domain Arrestin_N PF00339.24 XP_011271170.1 - 1.7e-08 34.4 0.8 1.2e-07 31.6 0.0 2.8 3 1 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 XP_011271170.1 - 0.03 14.4 0.3 0.66 10.0 0.0 2.8 3 1 0 3 3 3 0 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 XP_011271171.1 - 4.9e-11 42.6 0.2 1.5e-08 34.5 0.2 2.5 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 XP_011271171.1 - 0.00027 21.0 1.9 0.32 11.1 0.2 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Bul1_C PF04426.7 XP_011271171.1 - 0.00075 18.7 0.3 0.0016 17.6 0.0 1.7 2 0 0 2 2 2 1 Bul1 C terminus CYSTM PF12734.2 XP_011271171.1 - 0.031 14.3 3.8 0.037 14.1 0.1 2.3 2 0 0 2 2 2 0 Cysteine-rich TM module stress tolerance Snf7 PF03357.16 XP_011271173.1 - 4e-44 149.9 13.5 4.7e-44 149.7 9.4 1.0 1 0 0 1 1 1 1 Snf7 DUF2120 PF09893.4 XP_011271173.1 - 0.0008 19.3 0.9 0.0014 18.6 0.6 1.5 1 1 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2120) V_ATPase_I PF01496.14 XP_011271173.1 - 0.013 13.3 5.5 0.016 13.0 3.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Vir_act_alpha_C PF10400.4 XP_011271173.1 - 0.049 13.9 0.6 0.049 13.9 0.4 1.7 2 0 0 2 2 2 0 Virulence activator alpha C-term Sugarporin_N PF11471.3 XP_011271173.1 - 0.062 12.9 0.8 0.062 12.9 0.5 3.0 3 0 0 3 3 3 0 Maltoporin periplasmic N-terminal extension Prefoldin_2 PF01920.15 XP_011271173.1 - 0.082 12.6 0.2 0.082 12.6 0.1 3.5 2 1 1 3 3 3 0 Prefoldin subunit Mod_r PF07200.8 XP_011271173.1 - 0.13 12.2 15.5 0.34 10.8 1.7 2.7 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Exonuc_VII_L PF02601.10 XP_011271173.1 - 0.14 11.3 7.4 0.15 11.1 5.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Tropomyosin_1 PF12718.2 XP_011271173.1 - 0.34 10.7 15.1 0.11 12.3 7.6 2.1 1 1 1 2 2 2 0 Tropomyosin like Seryl_tRNA_N PF02403.17 XP_011271173.1 - 0.45 10.5 14.7 0.46 10.5 0.9 3.0 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain FlaC_arch PF05377.6 XP_011271173.1 - 0.66 9.9 6.9 1.3 8.9 0.1 3.2 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF342 PF03961.8 XP_011271173.1 - 0.83 7.9 13.6 0.5 8.7 6.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Mnd1 PF03962.10 XP_011271173.1 - 1.3 8.6 15.6 0.61 9.7 6.6 2.1 1 1 1 2 2 2 0 Mnd1 family FemAB PF02388.11 XP_011271173.1 - 1.7 7.2 8.8 1.2 7.7 4.0 1.8 1 1 1 2 2 2 0 FemAB family Atg14 PF10186.4 XP_011271173.1 - 2.4 7.0 12.8 3.6 6.4 8.9 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 GrpE PF01025.14 XP_011271173.1 - 2.4 7.6 11.3 1.6 8.2 5.8 2.0 1 1 1 2 2 2 0 GrpE DUF4446 PF14584.1 XP_011271173.1 - 2.7 7.8 8.8 4.6 7.0 2.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) OmpH PF03938.9 XP_011271173.1 - 3.6 7.5 19.1 2.6 7.9 9.2 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) NT-C2 PF10358.4 XP_011271175.1 - 2.5e-34 117.8 1.3 4.5e-34 116.9 0.9 1.5 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins zf-C3HC4_3 PF13920.1 XP_011271177.1 - 1.1e-08 34.5 3.7 1.9e-08 33.8 2.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 XP_011271177.1 - 8e-08 31.8 5.3 1.4e-07 31.0 3.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 XP_011271177.1 - 1.3e-07 31.3 5.4 2e-07 30.7 3.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 XP_011271177.1 - 1.5e-07 31.3 5.8 2.6e-07 30.5 4.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 XP_011271177.1 - 4e-07 29.6 6.7 6.5e-07 28.9 4.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 XP_011271177.1 - 0.00063 19.4 2.5 0.0018 17.9 1.8 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 XP_011271177.1 - 0.004 17.0 7.5 0.0066 16.2 5.2 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING SerH PF06873.6 XP_011271177.1 - 0.017 13.7 2.1 0.024 13.2 1.5 1.1 1 0 0 1 1 1 0 Cell surface immobilisation antigen SerH FYVE_2 PF02318.11 XP_011271177.1 - 0.087 12.7 0.8 0.14 12.1 0.6 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger DUF1299 PF06975.6 XP_011271177.1 - 2.3 8.1 10.8 6.7 6.6 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1299) FYVE PF01363.16 XP_011271177.1 - 6.2 6.8 7.0 22 5.0 4.6 2.0 1 1 0 1 1 1 0 FYVE zinc finger Ribosomal_L14 PF00238.14 XP_011271178.1 - 3.7e-32 110.6 0.0 4e-32 110.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e PI3_PI4_kinase PF00454.22 XP_011271179.1 - 6.2e-49 166.5 0.0 2.6e-48 164.5 0.0 2.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.3 XP_011271179.1 - 1.2e-26 93.2 5.4 1.2e-26 93.2 3.7 3.8 4 0 0 4 4 4 1 Telomere-length maintenance and DNA damage repair FATC PF02260.15 XP_011271179.1 - 1.1e-11 43.9 0.0 2.9e-11 42.5 0.0 1.8 1 0 0 1 1 1 1 FATC domain DUF2424 PF10340.4 XP_011271180.1 - 5e-23 81.3 2.6 6.7e-23 80.9 1.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_3 PF07859.8 XP_011271180.1 - 1.3e-10 41.2 0.0 1.7e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 XP_011271180.1 - 0.012 15.3 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family CRAL_TRIO PF00650.15 XP_011271181.1 - 4.3e-38 130.3 0.0 8e-38 129.4 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 XP_011271181.1 - 5.1e-14 52.1 0.4 1.7e-13 50.5 0.3 2.0 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Borrelia_orfD PF02999.9 XP_011271181.1 - 0.6 10.2 6.4 1 9.4 0.1 3.2 3 1 0 3 3 3 0 Borrelia orf-D family Elongin_A PF06881.6 XP_011271182.1 - 5.5e-13 49.2 6.7 1.8e-12 47.5 0.3 2.3 1 1 0 2 2 2 2 RNA polymerase II transcription factor SIII (Elongin) subunit A DUF605 PF04652.11 XP_011271182.1 - 1.8 7.8 19.7 2.4 7.4 13.6 1.1 1 0 0 1 1 1 0 Vta1 like Epimerase PF01370.16 XP_011271183.1 - 4.2e-14 52.5 0.0 6.7e-14 51.8 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 XP_011271183.1 - 7.4e-12 44.5 0.0 1.2e-11 43.8 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 XP_011271183.1 - 1.1e-09 37.5 0.0 7.4e-09 34.8 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 XP_011271183.1 - 2.7e-07 30.7 0.4 1.3e-06 28.5 0.3 2.0 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 XP_011271183.1 - 7e-07 29.3 0.0 4.2e-06 26.7 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 XP_011271183.1 - 1.8e-06 27.7 0.0 3.4e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 XP_011271183.1 - 0.0082 15.4 0.1 0.034 13.3 0.0 2.1 2 1 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.10 XP_011271183.1 - 0.011 14.6 0.0 0.02 13.8 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DapB_N PF01113.15 XP_011271183.1 - 0.098 12.5 0.0 0.52 10.2 0.0 2.2 3 0 0 3 3 3 0 Dihydrodipicolinate reductase, N-terminus zf-AN1 PF01428.11 XP_011271184.1 - 1.7e-11 43.7 12.0 3e-11 43.0 8.3 1.3 1 0 0 1 1 1 1 AN1-like Zinc finger YPEB PF14620.1 XP_011271184.1 - 0.059 12.3 0.9 0.077 11.9 0.6 1.1 1 0 0 1 1 1 0 YpeB sporulation PGC7_Stella PF15549.1 XP_011271184.1 - 5.4 6.9 12.0 0.35 10.8 4.0 2.1 2 0 0 2 2 2 0 PGC7/Stella/Dppa3 domain Pkinase PF00069.20 XP_011271185.1 - 5.5e-34 117.4 0.7 1.4e-33 116.1 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011271185.1 - 5.8e-14 51.7 0.0 9.8e-14 51.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 XP_011271185.1 - 0.0013 17.8 0.0 0.0023 17.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 XP_011271185.1 - 0.017 14.8 0.1 1.3 8.7 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 XP_011271185.1 - 0.036 13.3 0.5 0.15 11.3 0.0 2.3 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL MARVEL PF01284.18 XP_011271186.1 - 8.3e-30 103.5 14.4 1e-29 103.2 10.0 1.1 1 0 0 1 1 1 1 Membrane-associating domain Tetraspannin PF00335.15 XP_011271186.1 - 0.78 8.9 12.6 20 4.3 8.8 2.1 1 1 0 1 1 1 0 Tetraspanin family NCA2 PF08637.5 XP_011271187.1 - 3e-89 298.7 11.9 3e-89 298.7 8.3 2.8 3 0 0 3 3 3 1 ATP synthase regulation protein NCA2 SH3_1 PF00018.23 XP_011271188.1 - 9.6e-15 53.7 0.0 1.5e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 XP_011271188.1 - 5.7e-14 51.4 0.1 1e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 XP_011271188.1 - 1e-11 44.1 0.0 1.5e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain DUF605 PF04652.11 XP_011271188.1 - 0.5 9.7 26.5 0.65 9.3 18.3 1.1 1 0 0 1 1 1 0 Vta1 like Proteasome PF00227.21 XP_011271189.1 - 3.7e-47 160.0 3.1 1.4e-43 148.4 0.2 2.1 1 1 1 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 XP_011271189.1 - 1.9e-14 52.6 0.4 6.2e-14 51.0 0.1 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature FF PF01846.14 XP_011271190.1 - 3.1e-11 43.0 0.5 3.1e-11 43.0 0.4 3.1 2 1 1 3 3 3 1 FF domain WW PF00397.21 XP_011271190.1 - 3.2e-05 23.6 0.2 7.4e-05 22.5 0.1 1.7 1 0 0 1 1 1 1 WW domain MBD PF01429.14 XP_011271190.1 - 0.0059 16.1 0.1 0.025 14.1 0.0 2.1 1 1 1 2 2 2 1 Methyl-CpG binding domain SKN1 PF03935.10 XP_011271191.1 - 6.7e-248 822.8 5.4 8.9e-248 822.4 3.8 1.2 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Asp PF00026.18 XP_011271193.1 - 6.5e-41 140.6 4.1 1e-40 139.9 2.8 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 XP_011271193.1 - 0.00012 22.0 0.3 0.00069 19.5 0.1 2.3 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 XP_011271193.1 - 0.1 13.1 0.0 1.4 9.4 0.0 2.4 2 0 0 2 2 2 0 Aspartyl protease Asp PF00026.18 XP_011271194.1 - 3.7e-40 138.1 8.7 3.7e-40 138.1 6.0 3.0 3 1 0 3 3 3 1 Eukaryotic aspartyl protease Flocculin_t3 PF13928.1 XP_011271194.1 - 5.6e-11 42.3 16.7 5.6e-11 42.3 11.6 6.9 4 3 0 4 4 4 1 Flocculin type 3 repeat TAXi_C PF14541.1 XP_011271194.1 - 0.00016 21.2 0.0 0.0015 18.1 0.0 2.4 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Clathrin PF00637.15 XP_011271195.1 - 3.5e-197 645.9 48.3 5e-31 107.2 0.4 8.1 9 0 0 9 9 9 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 XP_011271195.1 - 1.1e-27 95.6 0.3 3.9e-27 93.9 0.2 2.0 1 0 0 1 1 1 1 Clathrin-H-link Clathrin_propel PF01394.15 XP_011271195.1 - 2.7e-20 71.1 6.8 0.0055 16.9 0.2 7.0 6 0 0 6 6 6 6 Clathrin propeller repeat Clathrin-link PF09268.5 XP_011271195.1 - 8.9e-06 24.6 4.8 1.1e-05 24.2 0.5 2.6 2 0 0 2 2 2 1 Clathrin, heavy-chain linker TPR_12 PF13424.1 XP_011271195.1 - 0.0043 16.9 5.2 11 5.9 0.0 6.2 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 XP_011271195.1 - 0.034 13.9 9.5 11 6.1 0.0 7.2 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_1 PF00515.23 XP_011271195.1 - 2.8 7.6 10.9 63 3.4 0.1 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat IF-2B PF01008.12 XP_011271196.1 - 4e-72 242.5 0.0 5.8e-72 242.0 0.0 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family Peptidase_M20 PF01546.23 XP_011271197.1 - 8.2e-21 74.3 0.0 1.5e-20 73.5 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 XP_011271197.1 - 7.9e-06 25.5 0.0 3.2e-05 23.6 0.0 2.0 1 1 0 1 1 1 1 Peptidase dimerisation domain Phytase-like PF13449.1 XP_011271197.1 - 0.046 12.9 0.1 0.074 12.3 0.1 1.2 1 0 0 1 1 1 0 Esterase-like activity of phytase Nitroreductase PF00881.19 XP_011271198.1 - 1.3e-06 28.3 0.0 2.1e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Nitroreductase family DUF512 PF04459.7 XP_011271198.1 - 0.099 11.7 0.1 0.37 9.8 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF512) Spermine_synth PF01564.12 XP_011271199.1 - 2.2e-100 334.6 0.1 2.6e-100 334.3 0.0 1.0 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_31 PF13847.1 XP_011271199.1 - 0.00018 21.1 0.0 0.00034 20.2 0.0 1.5 1 1 1 2 2 2 1 Methyltransferase domain DUF43 PF01861.11 XP_011271199.1 - 0.0038 16.2 0.0 0.0069 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF43 Methyltransf_12 PF08242.7 XP_011271199.1 - 0.0039 17.6 0.2 0.012 16.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 XP_011271199.1 - 0.015 15.8 0.0 0.025 15.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.13 XP_011271199.1 - 0.049 12.8 0.1 0.31 10.2 0.0 2.1 1 1 1 2 2 2 0 O-methyltransferase MTS PF05175.9 XP_011271199.1 - 0.064 12.6 0.0 0.088 12.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Hist_deacetyl PF00850.14 XP_011271200.1 - 5.4e-78 262.4 0.0 7.6e-78 261.9 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain RXT2_N PF08595.6 XP_011271200.1 - 0.18 11.5 4.9 0.38 10.5 3.4 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal Glyco_trans_1_4 PF13692.1 XP_011271201.1 - 8.8e-20 71.2 0.0 1.8e-19 70.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 XP_011271201.1 - 6.9e-14 51.6 0.0 1.6e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 XP_011271201.1 - 0.0065 16.1 0.0 0.014 15.1 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.1 XP_011271201.1 - 0.022 15.0 0.0 0.044 14.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 EF-hand_1 PF00036.27 XP_011271202.1 - 1.4e-20 70.9 9.1 1.9e-08 33.0 0.1 4.3 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 XP_011271202.1 - 2e-17 63.0 2.5 1.7e-14 53.6 0.1 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 XP_011271202.1 - 3.6e-16 57.5 5.7 7.8e-08 31.5 0.1 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 XP_011271202.1 - 4.1e-12 45.5 7.4 5.3e-07 29.1 0.2 3.5 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 XP_011271202.1 - 3.4e-09 35.6 8.6 4.3e-06 25.8 0.1 4.2 4 0 0 4 4 4 2 EF hand EF-hand_9 PF14658.1 XP_011271202.1 - 3.8e-07 29.9 0.1 1.3e-06 28.1 0.0 2.0 3 0 0 3 3 3 1 EF-hand domain UPF0154 PF03672.8 XP_011271202.1 - 4.3e-05 23.0 0.4 0.16 11.6 0.0 2.7 3 1 0 3 3 3 2 Uncharacterised protein family (UPF0154) SPARC_Ca_bdg PF10591.4 XP_011271202.1 - 5.7e-05 23.1 0.3 0.00013 21.9 0.0 1.6 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.8 XP_011271202.1 - 0.0019 17.7 0.1 0.043 13.3 0.0 2.0 2 0 0 2 2 2 1 Caleosin related protein EF-hand_4 PF12763.2 XP_011271202.1 - 0.002 17.8 0.2 0.0042 16.8 0.1 1.6 1 1 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand DUF217 PF02697.9 XP_011271202.1 - 0.052 13.7 1.2 0.12 12.6 0.1 2.1 2 1 1 3 3 3 0 Uncharacterized ACR, COG1753 CENP-L PF13092.1 XP_011271204.1 - 1.4e-14 54.2 3.0 6.3e-14 52.0 0.4 2.2 2 0 0 2 2 2 1 Kinetochore complex Sim4 subunit Fta1 Sin3_corepress PF08295.7 XP_011271204.1 - 0.047 13.4 0.8 0.26 11.0 0.2 2.1 2 0 0 2 2 2 0 Sin3 family co-repressor Methyltransf_11 PF08241.7 XP_011271205.1 - 3.4e-14 53.0 0.0 7.7e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 XP_011271205.1 - 2.1e-09 37.1 0.4 1.3e-08 34.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 XP_011271205.1 - 5.9e-09 35.3 0.0 9.2e-09 34.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 XP_011271205.1 - 2.3e-07 30.6 0.0 3.8e-07 29.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 XP_011271205.1 - 2.4e-07 31.1 0.0 7.2e-07 29.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 XP_011271205.1 - 7.6e-06 26.4 0.0 3.1e-05 24.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 XP_011271205.1 - 1.4e-05 25.4 0.0 4.1e-05 23.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_PK PF05891.7 XP_011271205.1 - 0.0019 17.5 0.0 0.0037 16.5 0.0 1.5 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_8 PF05148.10 XP_011271205.1 - 0.0075 15.9 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase MTS PF05175.9 XP_011271205.1 - 0.041 13.2 0.0 0.065 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain RrnaAD PF00398.15 XP_011271205.1 - 0.079 11.9 0.1 0.34 9.8 0.0 2.0 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase KRE9 PF05390.6 XP_011271206.1 - 3.3e-34 117.4 12.6 3.3e-34 117.4 8.7 1.5 2 0 0 2 2 2 1 Yeast cell wall synthesis protein KRE9/KNH1 GPI-anchored PF10342.4 XP_011271206.1 - 2.9e-14 53.3 0.5 2.9e-14 53.3 0.4 2.5 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family La PF05383.12 XP_011271207.1 - 2.1e-24 85.0 0.1 4e-24 84.1 0.1 1.5 1 0 0 1 1 1 1 La domain RRM_6 PF14259.1 XP_011271207.1 - 7.1e-12 45.1 0.1 1.8e-11 43.8 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 XP_011271207.1 - 1.8e-11 43.5 0.7 4e-11 42.3 0.5 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 XP_011271207.1 - 4.3e-07 29.6 0.3 9.4e-07 28.5 0.2 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DDHD PF02862.12 XP_011271207.1 - 0.12 12.2 7.2 0.22 11.2 5.0 1.5 1 0 0 1 1 1 0 DDHD domain Tom37_C PF11801.3 XP_011271207.1 - 0.9 9.3 6.2 1.7 8.4 4.3 1.4 1 0 0 1 1 1 0 Tom37 C-terminal domain Tim54 PF11711.3 XP_011271207.1 - 1.3 7.4 14.2 2.2 6.8 9.9 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CDC45 PF02724.9 XP_011271207.1 - 5.5 4.9 9.8 7.5 4.4 6.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Na_H_Exchanger PF00999.16 XP_011271208.1 - 1.6e-62 211.2 46.3 2.2e-62 210.7 32.1 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF2636 PF11120.3 XP_011271208.1 - 0.24 10.9 2.4 0.4 10.2 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2636) Mito_carr PF00153.22 XP_011271209.1 - 2.6e-47 158.4 5.1 1.3e-18 66.4 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein FoP_duplication PF13865.1 XP_011271210.1 - 3.5e-12 46.5 11.2 3.2e-06 27.4 1.7 2.9 2 1 1 3 3 3 2 C-terminal duplication domain of Friend of PRMT1 DUF3926 PF13080.1 XP_011271210.1 - 0.0075 15.7 0.0 4.9 6.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3926) Pox_A_type_inc PF04508.7 XP_011271210.1 - 0.008 15.8 0.2 7.2 6.6 0.0 3.4 3 0 0 3 3 3 1 Viral A-type inclusion protein repeat RRM_1 PF00076.17 XP_011271210.1 - 0.035 13.7 0.1 0.062 12.9 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 XP_011271211.1 - 4.3e-46 153.1 16.8 1.3e-07 31.2 0.0 7.8 7 0 0 7 7 7 7 WD domain, G-beta repeat PFU PF09070.6 XP_011271211.1 - 7.8e-44 148.4 0.3 2e-43 147.1 0.2 1.7 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) PUL PF08324.6 XP_011271211.1 - 1.9e-37 128.5 5.0 2.9e-37 127.9 3.5 1.3 1 0 0 1 1 1 1 PUL domain USP8_dimer PF08969.6 XP_011271211.1 - 0.014 15.3 1.0 0.036 14.0 0.7 1.7 1 0 0 1 1 1 0 USP8 dimerisation domain HMGL-like PF00682.14 XP_011271211.1 - 0.049 13.2 0.5 0.1 12.2 0.3 1.4 1 0 0 1 1 1 0 HMGL-like Syja_N PF02383.13 XP_011271212.1 - 2.6e-88 295.8 2.8 3.5e-88 295.4 1.9 1.2 1 0 0 1 1 1 1 SacI homology domain DUF4393 PF14337.1 XP_011271212.1 - 0.088 12.2 1.0 0.66 9.3 0.1 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4393) Meiosis_expr PF15163.1 XP_011271212.1 - 0.59 10.5 2.9 0.35 11.2 0.2 2.0 2 0 0 2 2 2 0 Meiosis-expressed IGPS PF00218.16 XP_011271213.1 - 2.2e-95 318.5 0.0 2.8e-95 318.1 0.0 1.1 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase GATase PF00117.23 XP_011271213.1 - 3.4e-57 193.0 0.2 5.8e-57 192.2 0.1 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 XP_011271213.1 - 4.4e-11 42.6 0.0 8.4e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.14 XP_011271213.1 - 0.0073 15.8 0.0 0.023 14.2 0.0 1.8 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain Antimicrobial10 PF08105.6 XP_011271213.1 - 0.016 14.8 0.0 0.052 13.1 0.0 1.9 1 0 0 1 1 1 0 Metchnikowin family Response_reg PF00072.19 XP_011271213.1 - 0.042 13.8 0.0 5.7 6.9 0.0 2.7 2 0 0 2 2 2 0 Response regulator receiver domain FAD_binding_2 PF00890.19 XP_011271213.1 - 0.1 11.4 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Septin PF00735.13 XP_011271214.1 - 4.7e-106 353.9 0.0 4.7e-106 353.9 0.0 1.6 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 XP_011271214.1 - 2.2e-08 34.0 0.0 4.3e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 XP_011271214.1 - 2e-05 23.8 0.5 8.6e-05 21.7 0.4 2.0 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 XP_011271214.1 - 0.00022 21.1 6.7 0.006 16.4 0.1 2.8 2 1 1 3 3 3 2 Dynamin family AIG1 PF04548.11 XP_011271214.1 - 0.00045 19.3 0.1 0.00045 19.3 0.1 2.1 2 1 0 2 2 2 1 AIG1 family IIGP PF05049.8 XP_011271214.1 - 0.0045 15.8 0.3 0.011 14.6 0.1 1.7 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) Miro PF08477.8 XP_011271214.1 - 0.0054 17.2 0.1 0.016 15.7 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein ABC_tran PF00005.22 XP_011271214.1 - 0.015 15.6 0.7 0.066 13.5 0.0 2.4 2 1 0 2 2 2 0 ABC transporter FeoB_N PF02421.13 XP_011271214.1 - 0.032 13.5 0.1 0.27 10.5 0.1 2.5 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_17 PF13207.1 XP_011271214.1 - 0.12 13.1 1.8 1 10.1 1.2 2.6 1 1 0 1 1 1 0 AAA domain LrgB PF04172.11 XP_011271215.1 - 3.7e-25 88.3 3.0 4.1e-24 84.9 0.0 2.4 2 0 0 2 2 2 2 LrgB-like family LrgA PF03788.9 XP_011271215.1 - 0.0025 17.4 2.0 0.0025 17.4 1.4 2.7 3 0 0 3 3 3 1 LrgA family Pkinase PF00069.20 XP_011271216.1 - 5.5e-56 189.5 0.2 1.2e-55 188.4 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011271216.1 - 3.9e-29 101.5 0.0 6.3e-29 100.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Globin PF00042.17 XP_011271216.1 - 0.15 12.4 0.0 0.41 11.0 0.0 1.7 1 0 0 1 1 1 0 Globin Kdo PF06293.9 XP_011271216.1 - 0.19 10.7 0.0 0.35 9.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 XP_011271217.1 - 6.1e-71 238.6 0.0 7.7e-71 238.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011271217.1 - 7.6e-42 143.1 0.0 1.1e-41 142.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 XP_011271217.1 - 9.6e-07 28.0 0.0 1.5e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 XP_011271217.1 - 0.013 14.6 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 XP_011271217.1 - 0.057 12.2 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 DnaJ PF00226.26 XP_011271218.1 - 9.9e-21 73.2 3.5 3.2e-20 71.6 2.4 2.0 2 0 0 2 2 2 1 DnaJ domain DUF780 PF05611.6 XP_011271218.1 - 0.14 12.9 7.3 0.47 11.1 5.0 1.9 1 0 0 1 1 1 0 Caenorhabditis elegans protein of unknown function (DUF780) MFS_1 PF07690.11 XP_011271219.1 - 1.4e-11 43.7 14.2 2.3e-11 43.0 9.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.11 XP_011271220.1 - 5.8e-11 41.7 2.3 7.4e-11 41.3 1.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4254 PF14063.1 XP_011271221.1 - 0.011 15.3 0.2 0.02 14.4 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4254) IBB PF01749.15 XP_011271221.1 - 0.029 14.5 1.8 0.029 14.5 1.3 2.6 3 0 0 3 3 3 0 Importin beta binding domain DUF334 PF03904.8 XP_011271221.1 - 0.55 9.5 7.9 0.89 8.8 5.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF334) Ribosomal_L14 PF00238.14 XP_011271223.1 - 8.7e-47 157.8 3.7 9.7e-47 157.7 2.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e KRE9 PF05390.6 XP_011271224.1 - 2.5e-35 121.0 11.1 5.3e-35 120.0 7.7 1.6 1 0 0 1 1 1 1 Yeast cell wall synthesis protein KRE9/KNH1 GPI-anchored PF10342.4 XP_011271224.1 - 1.9e-15 57.0 2.4 1.9e-15 57.0 1.7 2.5 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF3823 PF12866.2 XP_011271224.1 - 0.051 13.0 0.1 0.07 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3823) KRE9 PF05390.6 XP_011271225.1 - 6e-35 119.8 5.9 1.1e-34 119.0 4.1 1.4 1 0 0 1 1 1 1 Yeast cell wall synthesis protein KRE9/KNH1 GPI-anchored PF10342.4 XP_011271225.1 - 2.8e-10 40.5 1.2 9.6e-10 38.8 0.0 2.2 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Rep_fac-A_3 PF08661.6 XP_011271226.1 - 7.9e-25 86.8 0.0 9.1e-25 86.6 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 Ten1_2 PF15490.1 XP_011271226.1 - 0.00019 20.9 0.0 0.00026 20.5 0.0 1.2 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit TPR_11 PF13414.1 XP_011271227.1 - 2.9e-17 62.0 0.1 1.6e-12 46.9 0.0 2.3 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 XP_011271227.1 - 9.1e-11 40.8 0.2 0.00036 20.0 0.2 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 XP_011271227.1 - 4.4e-10 38.6 0.1 0.0013 18.4 0.2 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat RPAP3_C PF13877.1 XP_011271227.1 - 4.4e-08 32.9 0.1 1.5e-07 31.2 0.0 1.9 2 1 1 3 3 3 1 Potential Monad-binding region of RPAP3 TPR_19 PF14559.1 XP_011271227.1 - 3.1e-07 30.6 0.0 0.00028 21.1 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 XP_011271227.1 - 1e-05 26.0 0.1 0.023 15.3 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 XP_011271227.1 - 0.0001 21.8 0.1 0.011 15.5 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 XP_011271227.1 - 0.0011 18.8 0.0 0.09 12.6 0.0 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 XP_011271227.1 - 0.0011 18.5 0.5 0.054 13.2 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 XP_011271227.1 - 0.0014 19.0 0.0 0.2 12.4 0.0 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 XP_011271227.1 - 0.0039 17.0 0.1 0.28 11.0 0.1 2.4 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.1 XP_011271227.1 - 0.079 12.9 0.4 0.95 9.4 0.1 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 XP_011271227.1 - 0.09 13.0 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Alkyl sulfatase dimerisation TPR_17 PF13431.1 XP_011271227.1 - 0.12 12.5 1.0 0.57 10.5 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat UPF0029 PF01205.14 XP_011271228.1 - 1.6e-31 108.2 0.1 2.2e-31 107.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 XP_011271228.1 - 2.9e-09 36.8 0.1 6.9e-09 35.5 0.1 1.7 1 1 0 1 1 1 1 RWD domain MPP6 PF10175.4 XP_011271229.1 - 0.00067 19.9 1.9 0.00067 19.9 1.3 2.7 2 1 1 3 3 3 1 M-phase phosphoprotein 6 Utp14 PF04615.8 XP_011271229.1 - 0.0011 17.2 19.7 0.0013 17.0 13.6 1.1 1 0 0 1 1 1 1 Utp14 protein EAP30 PF04157.11 XP_011271229.1 - 0.017 14.2 2.6 0.015 14.4 1.2 1.3 1 1 0 1 1 1 0 EAP30/Vps36 family Neur_chan_memb PF02932.11 XP_011271229.1 - 7.5 6.3 8.9 10 5.9 6.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region WD40 PF00400.27 XP_011271230.1 - 7.3e-52 171.5 18.8 2e-10 40.1 0.1 11.8 12 0 0 12 12 12 8 WD domain, G-beta repeat Utp12 PF04003.7 XP_011271230.1 - 6.3e-27 93.6 0.2 9.4e-27 93.1 0.1 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.6 XP_011271230.1 - 4.9e-07 29.6 4.2 0.0014 18.4 0.0 5.2 4 1 1 5 5 5 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 XP_011271230.1 - 3.3e-06 25.6 1.9 0.09 11.0 0.0 4.1 5 0 0 5 5 5 2 Cytochrome D1 heme domain Nbas_N PF15492.1 XP_011271230.1 - 0.0033 16.5 0.2 6 5.8 0.0 3.8 3 1 0 3 3 3 2 Neuroblastoma-amplified sequence, N terminal VAD1-2 PF15310.1 XP_011271230.1 - 0.025 14.2 0.1 0.98 9.0 0.0 2.4 2 0 0 2 2 2 0 Vitamin A-deficiency (VAD) rat model signalling DNA_pol_phi PF04931.8 XP_011271230.1 - 0.4 8.3 15.9 0.65 7.6 11.0 1.4 1 0 0 1 1 1 0 DNA polymerase phi Astro_capsid PF03115.9 XP_011271230.1 - 0.78 7.9 3.2 1.1 7.4 2.2 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Atx10homo_assoc PF09759.4 XP_011271232.1 - 1.6e-33 114.4 1.0 1.6e-33 114.4 0.7 2.2 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain Thr_synth_N PF14821.1 XP_011271233.1 - 1.3e-29 101.9 0.1 1.6e-28 98.5 0.0 2.5 2 1 1 3 3 3 1 Threonine synthase N terminus PALP PF00291.20 XP_011271233.1 - 2.2e-17 63.2 0.0 4.2e-17 62.3 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme VAR1 PF05316.7 XP_011271233.1 - 0.016 13.8 0.1 0.028 13.0 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein (VAR1) DUF4287 PF14117.1 XP_011271233.1 - 0.063 12.9 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4287) SWIB PF02201.13 XP_011271235.1 - 3.2e-20 71.5 0.1 7.5e-20 70.3 0.0 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain WD40 PF00400.27 XP_011271236.1 - 5.7e-35 117.9 12.4 4.8e-08 32.5 0.1 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 XP_011271236.1 - 5.6e-25 87.0 0.4 1.1e-24 86.1 0.3 1.5 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Ribosomal_L9_N PF01281.14 XP_011271237.1 - 4.5e-09 35.4 0.0 7.8e-09 34.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain DNA_pol3_beta_3 PF02768.10 XP_011271237.1 - 0.0049 16.4 1.0 0.011 15.3 0.7 1.6 1 0 0 1 1 1 1 DNA polymerase III beta subunit, C-terminal domain MCM PF00493.18 XP_011271238.1 - 3.5e-141 469.8 0.2 4.7e-141 469.3 0.1 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 XP_011271238.1 - 2.2e-20 73.3 0.1 7.2e-20 71.6 0.1 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 XP_011271238.1 - 7.1e-06 25.3 0.0 0.00048 19.3 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 XP_011271238.1 - 1.6e-05 24.6 0.0 3.6e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 XP_011271238.1 - 0.00045 19.8 0.0 0.0018 17.9 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 XP_011271238.1 - 0.00088 19.4 0.5 0.24 11.6 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 XP_011271238.1 - 0.023 14.1 0.0 1.2 8.5 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase_2 PF13335.1 XP_011271238.1 - 0.04 14.3 0.3 0.16 12.3 0.2 2.1 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Phage_NinH PF06322.6 XP_011271238.1 - 0.046 13.3 0.4 11 5.6 0.2 2.6 2 0 0 2 2 2 0 Phage NinH protein CPSF73-100_C PF11718.3 XP_011271239.1 - 2.9e-67 226.1 0.6 5.3e-67 225.3 0.4 1.4 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 XP_011271239.1 - 2e-35 121.5 0.0 4.3e-35 120.3 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 XP_011271239.1 - 1e-11 44.8 1.1 2.3e-11 43.6 0.7 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 XP_011271239.1 - 1.5e-10 40.9 0.4 3e-10 39.9 0.3 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RMMBL PF07521.7 XP_011271239.1 - 4.1e-09 36.1 0.0 8.2e-09 35.1 0.0 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 XP_011271239.1 - 0.0025 17.5 1.2 0.0053 16.4 0.0 2.1 2 1 0 2 2 2 1 Beta-lactamase superfamily domain RF-1 PF00472.15 XP_011271240.1 - 2.1e-18 66.1 11.1 2.1e-18 66.1 7.7 3.2 1 1 0 2 2 2 1 RF-1 domain DUF1789 PF08748.6 XP_011271240.1 - 1 9.4 7.6 0.1 12.7 1.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1789) Fucose_iso_N2 PF07882.7 XP_011271240.1 - 1.9 8.1 7.9 1.7 8.2 4.6 1.6 1 1 0 1 1 1 0 L-fucose isomerase, second N-terminal domain Peptidase_S46 PF10459.4 XP_011271240.1 - 2.2 6.5 11.5 2.8 6.2 8.0 1.1 1 0 0 1 1 1 0 Peptidase S46 MFS_1 PF07690.11 XP_011271241.1 - 1.8e-14 53.2 25.6 1.8e-14 53.2 17.7 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 XP_011271241.1 - 6.7e-14 51.3 28.2 1.3e-13 50.3 19.6 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter ABC_tran PF00005.22 XP_011271243.1 - 1.2e-56 190.8 0.2 2.6e-33 115.2 0.0 2.9 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 XP_011271243.1 - 8.5e-50 169.6 38.2 2.6e-26 92.6 8.2 4.4 3 1 1 4 4 4 3 ABC transporter transmembrane region AAA_23 PF13476.1 XP_011271243.1 - 1.3e-10 41.9 22.6 2.6e-07 31.1 0.2 4.3 4 1 0 4 4 3 2 AAA domain SMC_N PF02463.14 XP_011271243.1 - 6.2e-10 38.6 10.6 0.00023 20.4 2.6 4.5 3 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 XP_011271243.1 - 1.2e-08 35.2 3.8 5.3e-06 26.6 2.4 5.6 6 2 1 7 7 4 2 AAA domain AAA_29 PF13555.1 XP_011271243.1 - 3.9e-08 32.6 0.4 0.0027 17.1 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 XP_011271243.1 - 4.2e-07 30.8 0.0 0.0078 17.0 0.0 3.2 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 XP_011271243.1 - 2.8e-06 26.6 0.0 0.025 13.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 T2SE PF00437.15 XP_011271243.1 - 4.7e-06 25.7 0.2 0.0032 16.4 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein MMR_HSR1 PF01926.18 XP_011271243.1 - 6.6e-06 26.0 0.1 0.029 14.3 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 XP_011271243.1 - 8.9e-06 26.1 0.9 0.32 11.5 0.0 3.5 3 0 0 3 3 2 2 Miro-like protein AAA_22 PF13401.1 XP_011271243.1 - 3.1e-05 24.1 0.1 0.29 11.2 0.0 3.7 4 0 0 4 4 4 2 AAA domain Zeta_toxin PF06414.7 XP_011271243.1 - 5.7e-05 22.3 0.0 0.15 11.1 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_16 PF13191.1 XP_011271243.1 - 0.00013 21.9 0.0 0.54 10.2 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 XP_011271243.1 - 0.00035 20.0 0.0 0.24 10.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 XP_011271243.1 - 0.0008 18.9 0.1 1.4 8.2 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family MobB PF03205.9 XP_011271243.1 - 0.0016 18.1 0.3 2.3 7.9 0.0 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 XP_011271243.1 - 0.0051 17.1 7.1 1.3 9.3 1.1 3.6 3 1 0 3 3 2 2 AAA domain AAA PF00004.24 XP_011271243.1 - 0.0055 16.8 0.5 5.4 7.2 0.0 3.8 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.14 XP_011271243.1 - 0.0064 15.9 0.4 0.51 9.7 0.0 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.12 XP_011271243.1 - 0.0065 16.3 3.8 0.45 10.2 0.0 3.6 4 0 0 4 4 4 1 Domain of unknown function DUF87 TrwB_AAD_bind PF10412.4 XP_011271243.1 - 0.0079 14.8 0.0 0.99 7.9 0.0 2.4 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_10 PF12846.2 XP_011271243.1 - 0.011 15.2 0.0 1.2 8.4 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain AAA_24 PF13479.1 XP_011271243.1 - 0.015 14.9 0.4 6 6.3 0.1 2.4 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 XP_011271243.1 - 0.016 14.6 0.1 0.52 9.7 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_33 PF13671.1 XP_011271243.1 - 0.018 14.9 0.0 3.8 7.3 0.0 2.9 3 0 0 3 3 2 0 AAA domain Dynamin_N PF00350.18 XP_011271243.1 - 0.032 14.0 3.2 5 6.9 0.0 3.4 3 0 0 3 3 3 0 Dynamin family AAA_5 PF07728.9 XP_011271243.1 - 0.045 13.4 0.0 10 5.8 0.0 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) ArgK PF03308.11 XP_011271243.1 - 0.083 11.6 0.0 0.18 10.5 0.0 1.4 1 0 0 1 1 1 0 ArgK protein AAA_30 PF13604.1 XP_011271243.1 - 0.085 12.4 0.0 13 5.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 XP_011271243.1 - 0.18 11.5 0.1 2.7 7.8 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain AAA_28 PF13521.1 XP_011271243.1 - 0.31 10.9 0.8 8 6.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain RRM_1 PF00076.17 XP_011271244.1 - 8.5e-16 57.3 8.4 2.4e-09 36.6 0.7 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 XP_011271244.1 - 6e-13 48.5 0.6 4.6e-06 26.5 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 XP_011271244.1 - 0.0027 17.5 0.3 0.31 10.9 0.0 2.9 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Band_3_cyto PF07565.8 XP_011271245.1 - 0.12 11.8 1.4 0.17 11.3 1.0 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Ribosomal_S13 PF00416.17 XP_011271246.1 - 3.3e-41 140.0 1.9 3.8e-41 139.8 1.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 XP_011271246.1 - 0.0013 17.4 0.1 0.0021 16.6 0.0 1.4 1 1 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Ribosomal_L4 PF00573.17 XP_011271247.1 - 6.9e-44 149.5 0.1 9.1e-44 149.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Rft-1 PF04506.8 XP_011271249.1 - 1.6e-120 403.0 40.9 1.9e-120 402.8 28.3 1.0 1 0 0 1 1 1 1 Rft protein Metallophos PF00149.23 XP_011271250.1 - 2.8e-11 43.1 4.8 5.4e-11 42.2 3.3 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Homeobox PF00046.24 XP_011271251.1 - 1.9e-15 56.2 4.8 3.8e-15 55.2 3.3 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 XP_011271251.1 - 0.024 14.3 0.8 0.094 12.4 0.6 2.1 1 0 0 1 1 1 0 Homeobox KN domain MRF_C2 PF13888.1 XP_011271251.1 - 0.031 14.0 1.8 0.079 12.7 1.2 1.7 1 0 0 1 1 1 0 Myelin gene regulatory factor C-terminal domain 2 MFS_1 PF07690.11 XP_011271252.1 - 3.9e-10 38.9 46.6 2e-09 36.6 31.9 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 XP_011271252.1 - 4.8e-05 21.7 27.4 0.00011 20.5 18.9 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 XP_011271253.1 - 3.3e-13 49.0 44.3 6.3e-13 48.1 29.8 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 XP_011271253.1 - 1.4e-05 23.4 30.3 3e-05 22.4 21.0 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 XP_011271254.1 - 3.5e-13 48.9 36.1 2e-12 46.5 25.4 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily PCI PF01399.22 XP_011271255.1 - 1.8e-22 79.6 0.6 1.8e-22 79.6 0.4 2.8 3 0 0 3 3 3 1 PCI domain Rpn3_C PF08375.6 XP_011271255.1 - 7.6e-22 77.4 2.9 1.8e-21 76.3 2.0 1.7 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI_Csn8 PF10075.4 XP_011271255.1 - 0.016 14.9 2.1 0.043 13.6 0.1 2.6 2 1 1 3 3 3 0 COP9 signalosome, subunit CSN8 Ribophorin_II PF05817.9 XP_011271256.1 - 1.5e-13 49.8 0.9 1.8e-13 49.6 0.6 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Got1 PF04178.7 XP_011271256.1 - 0.011 15.8 3.3 0.024 14.7 2.3 1.6 1 0 0 1 1 1 0 Got1/Sft2-like family DUF4218 PF13960.1 XP_011271257.1 - 0.0014 18.0 0.2 0.0058 16.0 0.1 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) SDA1 PF05285.7 XP_011271257.1 - 0.13 11.5 19.9 0.24 10.6 13.8 1.4 1 0 0 1 1 1 0 SDA1 CENP-T PF15511.1 XP_011271257.1 - 1.2 8.3 14.3 1.7 7.7 9.9 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF3245 PF11595.3 XP_011271257.1 - 1.2 9.4 9.2 3.3 7.9 6.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) Oxysterol_BP PF01237.13 XP_011271259.1 - 5e-91 304.8 3.2 5.9e-91 304.5 2.2 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein Ribosomal_L35Ae PF01247.13 XP_011271260.1 - 5.5e-42 141.4 1.1 6.2e-42 141.2 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 XP_011271260.1 - 7.3e-05 22.6 0.0 0.23 11.4 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain Phage_prot_Gp6 PF05133.9 XP_011271261.1 - 0.00032 19.3 0.5 0.05 12.1 0.0 2.3 2 0 0 2 2 2 2 Phage portal protein, SPP1 Gp6-like Flagellin_C PF00700.16 XP_011271261.1 - 0.068 13.3 0.0 11 6.2 0.0 3.4 3 0 0 3 3 3 0 Bacterial flagellin C-terminal helical region Pkinase PF00069.20 XP_011271262.1 - 3.1e-67 226.4 0.0 8.6e-67 225.0 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011271262.1 - 1.7e-38 132.1 0.0 3.1e-38 131.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 XP_011271262.1 - 5.3e-08 32.1 0.0 2e-07 30.2 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 XP_011271262.1 - 0.00028 19.9 0.3 0.0012 17.9 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 XP_011271262.1 - 0.021 14.5 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ribosomal_L18e PF00828.14 XP_011271263.1 - 9.5e-21 74.5 2.6 1.2e-20 74.1 0.9 1.8 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 HbrB PF08539.6 XP_011271264.1 - 8.3e-29 100.4 2.0 8.3e-29 100.4 1.4 1.5 2 0 0 2 2 2 1 HbrB-like Acetyltransf_13 PF13880.1 XP_011271264.1 - 0.016 14.9 0.0 0.054 13.2 0.0 1.9 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase Put_Phosphatase PF06888.7 XP_011271264.1 - 0.09 11.9 0.3 0.17 11.0 0.2 1.4 1 0 0 1 1 1 0 Putative Phosphatase Mon1 PF03164.9 XP_011271265.1 - 3.2e-103 345.5 3.6 4.1e-103 345.1 2.5 1.1 1 0 0 1 1 1 1 Trafficking protein Mon1 RRM_1 PF00076.17 XP_011271266.1 - 7.4e-57 188.8 0.2 9.3e-17 60.4 0.0 4.9 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 XP_011271266.1 - 4.1e-45 151.6 0.2 1.3e-12 47.4 0.0 4.7 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 XP_011271266.1 - 3.6e-20 71.5 0.6 2.5e-07 30.4 0.0 4.7 5 0 0 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AdoMet_MTase PF07757.8 XP_011271267.1 - 1.8e-45 153.6 0.1 2.9e-45 152.9 0.1 1.3 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.1 XP_011271267.1 - 0.011 15.3 0.2 0.52 9.9 0.0 2.7 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_23 PF13489.1 XP_011271267.1 - 0.026 14.2 0.0 0.062 13.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 XP_011271267.1 - 0.13 12.8 0.0 0.43 11.1 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.20 XP_011271268.1 - 1.8e-76 256.7 0.0 4.2e-76 255.5 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011271268.1 - 6e-36 123.8 0.0 8.7e-36 123.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 XP_011271268.1 - 0.0022 16.9 0.0 0.0029 16.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like MFS_1 PF07690.11 XP_011271270.1 - 4.6e-26 91.3 22.3 5.9e-26 91.0 15.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.11 XP_011271271.1 - 3e-45 154.4 26.2 3e-45 154.4 18.1 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 XP_011271271.1 - 2.5e-11 42.8 10.3 2.5e-11 42.8 7.1 2.6 3 1 0 3 3 3 1 Sugar (and other) transporter PBP1_TM PF14812.1 XP_011271271.1 - 1.3 9.4 6.6 0.096 12.9 1.0 1.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Stm1_N PF09598.5 XP_011271272.1 - 2.1e-12 47.5 6.0 2.1e-12 47.5 4.2 3.5 4 0 0 4 4 4 2 Stm1 ATP-synt_B PF00430.13 XP_011271272.1 - 0.12 12.1 2.7 0.27 11.0 1.9 1.6 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Sec7 PF01369.15 XP_011271273.1 - 4.3e-66 222.2 0.3 1.2e-65 220.7 0.2 1.8 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 XP_011271273.1 - 1.4e-56 190.5 6.2 1.4e-56 190.5 4.3 4.3 5 0 0 5 5 5 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 XP_011271273.1 - 5.3e-27 93.1 10.4 2.5e-26 91.0 0.2 4.4 4 0 0 4 4 4 2 Domain of unknown function (DUF1981) DUF4256 PF14066.1 XP_011271273.1 - 0.011 15.2 0.2 0.024 14.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4256) Arm PF00514.18 XP_011271273.1 - 0.056 13.3 0.2 5.8 6.8 0.0 3.2 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat NUDIX PF00293.23 XP_011271274.1 - 1.1e-14 54.2 0.0 2e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain Pribosyl_synth PF14572.1 XP_011271275.1 - 6.1e-44 149.9 1.5 1.1e-43 149.1 1.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 XP_011271275.1 - 6.5e-35 119.3 0.2 6.4e-34 116.1 0.0 2.5 2 1 0 3 3 3 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 XP_011271275.1 - 2e-12 46.9 0.1 8.1e-12 44.9 0.1 2.0 1 1 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 XP_011271275.1 - 0.019 14.1 0.2 0.032 13.4 0.1 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Pkinase PF00069.20 XP_011271276.1 - 1.7e-58 197.8 0.0 4.7e-58 196.3 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011271276.1 - 6.5e-22 77.8 0.0 1.2e-21 76.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 XP_011271276.1 - 0.1 12.3 0.0 0.26 10.9 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF21 PF01595.15 XP_011271277.1 - 2.7e-30 105.0 0.1 4.3e-30 104.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 XP_011271277.1 - 3.9e-05 23.3 0.0 0.093 12.5 0.0 2.6 2 0 0 2 2 2 2 CBS domain T4_Gp59_C PF08994.5 XP_011271277.1 - 0.016 15.3 0.0 0.047 13.8 0.0 1.8 1 0 0 1 1 1 0 T4 gene Gp59 loader of gp41 DNA helicase C-term NAP PF00956.13 XP_011271278.1 - 2.1e-80 269.4 22.4 2.1e-80 269.4 15.5 2.0 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Methyltransf_33 PF10017.4 XP_011271279.1 - 0.049 13.5 0.1 0.27 11.1 0.0 2.1 2 0 0 2 2 2 0 Histidine-specific methyltransferase, SAM-dependent DUF2413 PF10310.4 XP_011271282.1 - 4.7e-98 328.9 30.7 5.4e-98 328.6 21.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) Ashwin PF15323.1 XP_011271282.1 - 0.94 9.4 19.3 0.043 13.8 8.0 2.2 2 0 0 2 2 2 0 Developmental protein DUF1687 PF07955.6 XP_011271283.1 - 1.4e-23 83.3 0.1 1.2e-21 77.0 0.1 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1687) FMN_red PF03358.10 XP_011271284.1 - 1.7e-08 34.1 0.0 2.5e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.20 XP_011271284.1 - 9e-07 28.9 0.0 1.2e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_2 PF02525.12 XP_011271284.1 - 0.0021 17.5 0.0 0.0029 17.1 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold CN_hydrolase PF00795.17 XP_011271285.1 - 6.1e-23 81.1 0.0 1e-22 80.4 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Acetyltransf_1 PF00583.19 XP_011271286.1 - 3e-06 27.1 0.0 2.4e-05 24.2 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 XP_011271286.1 - 0.00065 19.8 0.0 0.00086 19.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 XP_011271286.1 - 0.0084 16.0 0.0 0.018 14.9 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 XP_011271286.1 - 0.097 12.8 0.0 0.15 12.2 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain YqbF PF14553.1 XP_011271286.1 - 0.38 10.4 1.8 29 4.4 0.0 2.9 3 0 0 3 3 3 0 YqbF, hypothetical protein domain zf-H2C2 PF09337.5 XP_011271288.1 - 1.6e-20 72.2 3.1 1.6e-20 72.2 2.1 2.4 2 0 0 2 2 2 1 His(2)-Cys(2) zinc finger Acetyltransf_1 PF00583.19 XP_011271288.1 - 2.3e-05 24.3 0.0 4.9e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 XP_011271288.1 - 0.0099 16.0 0.0 0.0099 16.0 0.0 2.4 4 0 0 4 4 4 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 XP_011271288.1 - 0.069 13.2 0.0 0.069 13.2 0.0 2.4 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain CPSase_L_D2 PF02786.12 XP_011271289.1 - 6.1e-117 388.3 1.0 2.9e-85 284.8 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.17 XP_011271289.1 - 4.6e-48 162.0 0.0 1.3e-47 160.5 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 XP_011271289.1 - 9.4e-45 152.4 0.0 2e-44 151.3 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase class-I OTCace_N PF02729.16 XP_011271289.1 - 2e-41 140.9 0.0 4.8e-41 139.7 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.14 XP_011271289.1 - 4.8e-41 139.3 0.1 1.5e-40 137.8 0.1 1.9 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_L_chain PF00289.17 XP_011271289.1 - 2.7e-40 136.8 0.0 2.8e-19 69.2 0.0 3.1 3 0 0 3 3 3 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 XP_011271289.1 - 1.2e-35 122.8 0.1 4e-21 75.5 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain OTCace PF00185.19 XP_011271289.1 - 4.7e-33 114.3 0.0 1.4e-32 112.7 0.0 1.9 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ATPgrasp_Ter PF15632.1 XP_011271289.1 - 5.2e-23 81.3 0.1 5.4e-12 45.1 0.0 3.4 3 0 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon MGS PF02142.17 XP_011271289.1 - 7.7e-22 77.0 0.0 5.3e-21 74.3 0.0 2.6 2 0 0 2 2 2 1 MGS-like domain Dala_Dala_lig_C PF07478.8 XP_011271289.1 - 4.7e-17 62.0 2.5 4e-08 32.9 0.3 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 XP_011271289.1 - 1.2e-14 54.0 0.3 4.3e-06 26.1 0.1 2.5 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.8 XP_011271289.1 - 3.1e-06 26.7 0.0 7.8e-05 22.2 0.0 2.5 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.9 XP_011271289.1 - 3.3e-06 27.0 1.5 0.024 14.5 0.2 2.7 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.14 XP_011271289.1 - 0.0026 17.3 0.3 2.9 7.3 0.0 2.9 2 1 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DJ-1_PfpI PF01965.19 XP_011271289.1 - 0.0045 16.4 0.0 0.012 15.1 0.0 1.6 1 0 0 1 1 1 1 DJ-1/PfpI family TrkH PF02386.11 XP_011271290.1 - 5.7e-134 446.1 23.5 3.8e-133 443.4 8.6 2.1 2 0 0 2 2 2 2 Cation transport protein Pkinase PF00069.20 XP_011271291.1 - 5.2e-58 196.2 0.0 7.8e-58 195.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011271291.1 - 7.3e-41 139.9 0.0 1.1e-40 139.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 XP_011271291.1 - 8.6e-05 21.6 0.0 0.00014 20.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 XP_011271291.1 - 0.0085 14.9 0.1 0.014 14.2 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Pox_ser-thr_kin PF05445.6 XP_011271291.1 - 0.028 13.2 0.0 0.045 12.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 XP_011271291.1 - 0.13 11.5 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 XP_011271291.1 - 0.22 11.2 0.0 0.98 9.0 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Skp1 PF01466.14 XP_011271292.1 - 2.2e-36 123.7 0.6 3.8e-36 122.9 0.4 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 XP_011271292.1 - 1.9e-21 75.8 0.1 3.3e-21 75.1 0.1 1.4 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain BTB PF00651.26 XP_011271292.1 - 0.05 13.6 0.0 0.4 10.6 0.0 2.1 1 1 0 1 1 1 0 BTB/POZ domain GRAM PF02893.15 XP_011271293.1 - 1.5e-18 66.0 0.1 3.3e-18 64.9 0.0 1.6 1 0 0 1 1 1 1 GRAM domain DUF912 PF06024.7 XP_011271293.1 - 1.4 8.9 0.0 1.4 8.9 0.0 4.1 3 1 1 4 4 4 0 Nucleopolyhedrovirus protein of unknown function (DUF912) EXS PF03124.9 XP_011271295.1 - 4.4e-67 226.5 29.2 5e-67 226.3 20.2 1.0 1 0 0 1 1 1 1 EXS family Swi5 PF07061.6 XP_011271296.1 - 3.2e-20 71.6 6.6 3.6e-20 71.5 4.6 1.0 1 0 0 1 1 1 1 Swi5 HAUS-augmin3 PF14932.1 XP_011271296.1 - 0.011 14.8 0.4 0.013 14.7 0.3 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 YlqD PF11068.3 XP_011271296.1 - 0.1 12.6 6.1 0.13 12.2 4.3 1.0 1 0 0 1 1 1 0 YlqD protein RsbU_N PF08673.5 XP_011271296.1 - 0.23 11.5 2.4 0.34 10.9 1.6 1.6 1 1 0 1 1 1 0 Phosphoserine phosphatase RsbU, N-terminal domain IMS PF00817.15 XP_011271297.1 - 2.6e-38 131.1 0.0 5.7e-38 130.0 0.0 1.6 1 1 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 XP_011271297.1 - 2e-09 37.4 0.0 4.4e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 XP_011271297.1 - 0.0002 21.2 0.0 0.00069 19.5 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif PASTA PF03793.14 XP_011271298.1 - 0.071 12.7 0.0 0.21 11.2 0.0 1.7 1 0 0 1 1 1 0 PASTA domain MFS_1 PF07690.11 XP_011271299.1 - 2.1e-42 145.1 34.1 8.2e-42 143.1 23.7 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily ESSS PF10183.4 XP_011271299.1 - 0.21 11.9 0.0 0.98 9.8 0.0 2.2 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Zip PF02535.17 XP_011271300.1 - 0.11 11.5 0.2 0.13 11.2 0.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter YCII PF03795.9 XP_011271302.1 - 6.6e-05 23.0 0.0 8.2e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain Lipase_GDSL PF00657.17 XP_011271303.1 - 6.3e-24 85.1 0.0 7.6e-24 84.8 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 XP_011271303.1 - 1.9e-21 77.0 0.0 2.2e-21 76.7 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Isochorismatase PF00857.15 XP_011271303.1 - 0.043 13.7 0.0 0.065 13.1 0.0 1.2 1 0 0 1 1 1 0 Isochorismatase family Profilin PF00235.14 XP_011271304.1 - 2.7e-40 137.2 0.2 3e-40 137.0 0.1 1.0 1 0 0 1 1 1 1 Profilin Profilin PF00235.14 XP_011271305.1 - 6.7e-32 110.1 0.0 7.5e-32 109.9 0.0 1.0 1 0 0 1 1 1 1 Profilin Leo1 PF04004.8 XP_011271306.1 - 1.9e-41 141.6 0.0 1.9e-41 141.6 0.0 3.5 2 2 1 4 4 4 1 Leo1-like protein Glyco_hydro_18 PF00704.23 XP_011271307.1 - 1.5e-87 294.2 7.9 2e-87 293.8 5.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 GPP34 PF05719.6 XP_011271308.1 - 1.4e-57 195.0 0.0 1.8e-57 194.7 0.0 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) UCH PF00443.24 XP_011271309.1 - 3.9e-52 177.0 1.8 1.2e-51 175.4 1.3 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.1 XP_011271309.1 - 6.8e-41 137.5 6.2 4e-13 48.5 0.1 4.9 4 0 0 4 4 4 4 A repeated domain in UCH-protein UCH_1 PF13423.1 XP_011271309.1 - 2.2e-09 37.2 1.4 8.4e-05 22.1 0.1 2.6 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUF948 PF06103.6 XP_011271309.1 - 0.011 15.6 1.4 0.19 11.6 0.2 3.7 5 0 0 5 5 5 0 Bacterial protein of unknown function (DUF948) Uds1 PF15456.1 XP_011271309.1 - 0.071 13.1 1.1 0.19 11.7 0.8 1.6 1 0 0 1 1 1 0 Up-regulated During Septation BCS1_N PF08740.6 XP_011271310.1 - 5.5e-49 166.3 0.0 9.7e-49 165.5 0.0 1.4 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 XP_011271310.1 - 1.4e-21 77.1 0.0 2.2e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 XP_011271310.1 - 1.2e-05 26.1 0.0 2.2e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 XP_011271310.1 - 0.0016 18.3 0.0 0.0032 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 XP_011271310.1 - 0.0021 18.0 0.0 0.0039 17.2 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 XP_011271310.1 - 0.0031 17.6 0.0 0.008 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.1 XP_011271310.1 - 0.004 17.1 0.1 0.0068 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 XP_011271310.1 - 0.004 16.5 0.0 0.0077 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 XP_011271310.1 - 0.0056 16.9 0.0 0.018 15.3 0.0 1.8 2 0 0 2 2 1 1 AAA domain Zeta_toxin PF06414.7 XP_011271310.1 - 0.0068 15.5 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_5 PF07728.9 XP_011271310.1 - 0.0081 15.8 0.0 0.018 14.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 XP_011271310.1 - 0.0094 15.0 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 XP_011271310.1 - 0.0099 15.6 0.0 0.045 13.4 0.0 2.1 2 1 0 2 2 2 1 Part of AAA domain AAA_14 PF13173.1 XP_011271310.1 - 0.0099 15.7 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 XP_011271310.1 - 0.012 14.5 0.0 0.019 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ABC_tran PF00005.22 XP_011271310.1 - 0.016 15.5 0.0 0.028 14.7 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_24 PF13479.1 XP_011271310.1 - 0.017 14.7 0.0 0.052 13.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 XP_011271310.1 - 0.022 14.4 0.0 0.097 12.3 0.0 1.9 2 0 0 2 2 2 0 Archaeal ATPase AAA_29 PF13555.1 XP_011271310.1 - 0.038 13.5 0.0 0.082 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain KaiC PF06745.8 XP_011271310.1 - 0.041 13.0 0.0 0.073 12.1 0.0 1.3 1 0 0 1 1 1 0 KaiC Miro PF08477.8 XP_011271310.1 - 0.053 14.0 0.0 0.11 13.0 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein RNA_helicase PF00910.17 XP_011271310.1 - 0.056 13.6 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 XP_011271310.1 - 0.062 12.9 0.0 0.3 10.7 0.0 1.9 1 1 1 2 2 2 0 NACHT domain UPF0079 PF02367.12 XP_011271310.1 - 0.069 12.7 0.0 0.56 9.8 0.0 2.4 2 1 1 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 XP_011271310.1 - 0.095 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 XP_011271310.1 - 0.096 12.9 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Herpes_DNAp_acc PF04929.7 XP_011271310.1 - 0.2 10.6 0.1 0.29 10.0 0.0 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor APC2 PF08672.6 XP_011271312.1 - 0.0017 18.5 0.6 0.031 14.5 0.0 2.3 2 0 0 2 2 2 1 Anaphase promoting complex (APC) subunit 2 EFF-AFF PF14884.1 XP_011271312.1 - 0.0032 15.6 0.1 0.0048 15.0 0.1 1.2 1 0 0 1 1 1 1 Type I membrane glycoproteins cell-cell fusogen Stb3 PF10330.4 XP_011271314.1 - 6.2e-29 99.5 0.3 4.9e-28 96.6 0.1 2.3 2 0 0 2 2 2 1 Putative Sin3 binding protein UPF0240 PF06784.6 XP_011271314.1 - 0.027 14.1 0.4 0.027 14.1 0.2 2.5 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0240) DUF3043 PF11241.3 XP_011271316.1 - 0.012 15.1 0.1 0.04 13.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) HTH_Tnp_Mu_1 PF02316.11 XP_011271316.1 - 0.026 14.2 0.0 0.96 9.1 0.0 2.4 2 0 0 2 2 2 0 Mu DNA-binding domain CTP_transf_1 PF01148.15 XP_011271316.1 - 0.082 12.5 29.2 3.7 7.1 20.2 2.9 1 1 0 1 1 1 0 Cytidylyltransferase family Acyltransferase PF01553.16 XP_011271317.1 - 2.6e-32 111.0 0.0 4e-32 110.4 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase DUF3437 PF11919.3 XP_011271318.1 - 1.7e-27 94.9 0.0 4.9e-27 93.4 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) eIF-3c_N PF05470.7 XP_011271319.1 - 4.5e-160 533.6 18.7 4.6e-124 414.7 1.2 3.1 1 1 2 3 3 3 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 XP_011271319.1 - 1.1e-12 48.2 1.5 3.7e-12 46.4 0.3 2.6 2 0 0 2 2 2 1 PCI domain ATP_bind_3 PF01171.15 XP_011271320.1 - 6.4e-19 68.1 0.0 1.4e-18 66.9 0.0 1.6 1 0 0 1 1 1 1 PP-loop family DUF2392 PF10288.4 XP_011271320.1 - 0.0013 19.0 0.0 0.0028 17.9 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) tRNA_Me_trans PF03054.11 XP_011271320.1 - 0.0023 16.5 0.0 0.0041 15.7 0.0 1.4 1 1 0 1 1 1 1 tRNA methyl transferase Esterase PF00756.15 XP_011271321.1 - 1.3e-05 24.7 0.0 1.8e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.2 XP_011271321.1 - 5.1e-05 23.2 0.0 7e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 XP_011271321.1 - 0.00079 19.2 0.0 0.0015 18.3 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 XP_011271321.1 - 0.0013 18.0 0.0 0.0019 17.4 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Tannase PF07519.6 XP_011271321.1 - 0.024 13.3 0.0 0.035 12.8 0.0 1.3 1 0 0 1 1 1 0 Tannase and feruloyl esterase ABC_tran PF00005.22 XP_011271324.1 - 4.8e-49 166.1 0.1 1.4e-23 83.6 0.0 2.6 3 0 0 3 3 2 2 ABC transporter ABC_tran_2 PF12848.2 XP_011271324.1 - 9.7e-20 70.2 2.1 9.7e-20 70.2 1.4 2.8 3 0 0 3 3 2 1 ABC transporter AAA_21 PF13304.1 XP_011271324.1 - 1.2e-19 71.4 1.6 0.00064 19.7 0.0 4.3 2 2 1 4 4 4 4 AAA domain DUF258 PF03193.11 XP_011271324.1 - 1e-09 37.7 0.0 3.7e-05 22.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 SMC_N PF02463.14 XP_011271324.1 - 2e-09 36.9 0.5 0.12 11.6 0.1 4.5 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 XP_011271324.1 - 5.2e-09 35.5 0.0 0.0031 16.9 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 XP_011271324.1 - 8.2e-09 36.0 0.1 0.022 15.0 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 XP_011271324.1 - 5.9e-08 33.5 0.0 0.0075 17.0 0.0 3.1 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 XP_011271324.1 - 9.3e-08 32.0 0.0 0.015 15.2 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.1 XP_011271324.1 - 1.2e-07 31.9 0.0 0.011 15.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 XP_011271324.1 - 3.8e-07 30.2 0.0 0.02 14.8 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain Miro PF08477.8 XP_011271324.1 - 5.8e-07 30.0 0.0 0.018 15.5 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_28 PF13521.1 XP_011271324.1 - 1e-06 28.7 0.0 0.0069 16.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 XP_011271324.1 - 1.1e-06 28.9 0.0 0.025 14.9 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA PF00004.24 XP_011271324.1 - 6.1e-06 26.4 0.0 0.027 14.6 0.0 3.0 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.1 XP_011271324.1 - 9.5e-06 24.9 0.0 0.16 10.9 0.0 3.5 3 1 1 4 4 3 2 AAA ATPase domain RNA_helicase PF00910.17 XP_011271324.1 - 1.4e-05 25.2 0.1 0.16 12.1 0.0 2.8 3 0 0 3 3 2 2 RNA helicase NACHT PF05729.7 XP_011271324.1 - 2.3e-05 24.1 0.3 0.22 11.1 0.0 2.7 3 0 0 3 3 2 2 NACHT domain AAA_33 PF13671.1 XP_011271324.1 - 9.3e-05 22.3 0.0 0.065 13.1 0.0 2.9 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 XP_011271324.1 - 0.00011 21.9 0.1 0.006 16.3 0.1 2.9 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 XP_011271324.1 - 0.00011 21.9 0.1 0.38 10.4 0.0 2.8 3 0 0 3 3 3 2 Archaeal ATPase AAA_14 PF13173.1 XP_011271324.1 - 0.00025 20.9 0.0 1.3 8.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 XP_011271324.1 - 0.00028 20.4 0.0 0.28 10.5 0.0 2.7 2 0 0 2 2 2 1 AAA-like domain Dynamin_N PF00350.18 XP_011271324.1 - 0.00038 20.3 0.6 0.4 10.4 0.0 3.6 2 1 1 3 3 3 1 Dynamin family AAA_5 PF07728.9 XP_011271324.1 - 0.00087 19.0 0.1 1.9 8.1 0.0 2.7 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) ArgK PF03308.11 XP_011271324.1 - 0.0013 17.5 0.0 0.67 8.6 0.0 2.7 3 0 0 3 3 3 1 ArgK protein FeoB_N PF02421.13 XP_011271324.1 - 0.0014 17.9 0.0 1 8.6 0.0 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B NB-ARC PF00931.17 XP_011271324.1 - 0.0017 17.2 0.0 0.78 8.5 0.0 3.0 2 1 0 2 2 2 1 NB-ARC domain AAA_25 PF13481.1 XP_011271324.1 - 0.0023 17.3 0.0 2 7.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain VirE PF05272.6 XP_011271324.1 - 0.004 16.6 0.1 0.35 10.3 0.0 2.6 3 0 0 3 3 2 1 Virulence-associated protein E DAP3 PF10236.4 XP_011271324.1 - 0.0042 16.0 1.8 0.8 8.5 0.0 2.9 3 0 0 3 3 3 1 Mitochondrial ribosomal death-associated protein 3 MCM PF00493.18 XP_011271324.1 - 0.0059 15.4 0.5 4.6 5.9 0.0 3.0 3 0 0 3 3 3 0 MCM2/3/5 family SbcCD_C PF13558.1 XP_011271324.1 - 0.0062 16.4 0.3 0.48 10.3 0.0 3.1 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit PduV-EutP PF10662.4 XP_011271324.1 - 0.0066 15.9 0.4 5.8 6.4 0.0 3.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation T2SE PF00437.15 XP_011271324.1 - 0.0083 15.0 0.0 0.23 10.3 0.0 2.5 2 1 0 2 2 2 1 Type II/IV secretion system protein NTPase_1 PF03266.10 XP_011271324.1 - 0.011 15.5 0.0 0.54 9.9 0.0 2.6 2 0 0 2 2 2 0 NTPase DUF2813 PF11398.3 XP_011271324.1 - 0.012 14.6 1.1 0.58 9.1 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2813) DUF815 PF05673.8 XP_011271324.1 - 0.016 14.1 0.0 2.6 6.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Septin PF00735.13 XP_011271324.1 - 0.029 13.3 0.1 8.6 5.2 0.0 2.6 3 0 0 3 3 3 0 Septin Ras PF00071.17 XP_011271324.1 - 0.037 13.4 0.0 8.9 5.6 0.0 2.4 2 0 0 2 2 2 0 Ras family Rad17 PF03215.10 XP_011271324.1 - 0.039 12.6 0.0 1.6 7.2 0.0 2.5 3 0 0 3 3 3 0 Rad17 cell cycle checkpoint protein DUF2500 PF10694.4 XP_011271325.1 - 0.38 10.7 2.6 0.83 9.6 1.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) PNRC PF15365.1 XP_011271326.1 - 0.00088 19.2 0.3 0.00088 19.2 0.2 2.8 3 1 0 3 3 3 1 Proline-rich nuclear receptor coactivator MIP-T3 PF10243.4 XP_011271326.1 - 0.93 7.8 19.3 0.99 7.7 13.4 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Utp14 PF04615.8 XP_011271326.1 - 2.4 6.2 18.6 2.6 6.1 12.9 1.0 1 0 0 1 1 1 0 Utp14 protein GPCR_chapero_1 PF11904.3 XP_011271326.1 - 4.8 6.2 15.1 6.4 5.8 10.5 1.2 1 0 0 1 1 1 0 GPCR-chaperone DUF2142 PF09913.4 XP_011271326.1 - 9.2 4.8 5.8 13 4.3 4.1 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2142) PMSR PF01625.16 XP_011271327.1 - 9.4e-37 126.2 0.3 1.1e-36 126.0 0.2 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase PALP PF00291.20 XP_011271328.1 - 9.9e-47 159.6 0.4 1.3e-46 159.2 0.3 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Candida_ALS_N PF11766.3 XP_011271329.1 - 9.3e-52 175.3 4.5 9.3e-52 175.3 3.1 2.8 3 1 1 4 4 4 1 Cell-wall agglutinin N-terminal ligand-sugar binding DBB PF14545.1 XP_011271329.1 - 0.31 10.5 1.4 93 2.5 0.0 4.1 3 1 2 5 5 5 0 Dof, BCAP, and BANK (DBB) motif, MFS_1 PF07690.11 XP_011271330.1 - 9.3e-34 116.6 9.7 9.3e-34 116.6 6.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily UPF0016 PF01169.14 XP_011271330.1 - 0.022 14.9 0.3 0.022 14.9 0.2 3.3 3 0 0 3 3 3 0 Uncharacterized protein family UPF0016 DZR PF12773.2 XP_011271331.1 - 1.6 8.5 7.6 1.8 8.4 0.2 2.7 2 0 0 2 2 2 0 Double zinc ribbon zinc_ribbon_2 PF13240.1 XP_011271331.1 - 2.5 7.7 6.3 0.87 9.1 0.1 3.1 3 0 0 3 3 3 0 zinc-ribbon domain ABC_membrane PF00664.18 XP_011271332.1 - 1.3e-60 205.1 35.1 9.5e-35 120.3 11.7 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 XP_011271332.1 - 6.1e-51 172.3 3.4 4.7e-30 104.6 0.1 3.1 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.14 XP_011271332.1 - 3.3e-11 42.8 8.0 7.1e-05 22.1 0.4 4.1 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 XP_011271332.1 - 2.7e-07 29.8 1.5 0.0011 18.2 0.2 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 XP_011271332.1 - 5.8e-07 28.9 3.0 0.0011 18.4 0.3 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 XP_011271332.1 - 7.3e-05 23.2 0.1 0.67 10.4 0.1 3.0 2 0 0 2 2 2 2 Miro-like protein FtsK_SpoIIIE PF01580.13 XP_011271332.1 - 0.0012 18.3 0.0 0.18 11.2 0.0 2.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_25 PF13481.1 XP_011271332.1 - 0.0015 17.9 0.1 2.3 7.5 0.0 3.4 4 0 0 4 4 4 2 AAA domain MMR_HSR1 PF01926.18 XP_011271332.1 - 0.0021 17.9 1.8 0.53 10.2 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase Zeta_toxin PF06414.7 XP_011271332.1 - 0.0071 15.4 0.5 0.44 9.6 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_16 PF13191.1 XP_011271332.1 - 0.016 15.1 2.0 0.35 10.8 0.1 2.8 2 1 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.1 XP_011271332.1 - 0.022 15.0 14.5 1.6 9.0 4.7 3.7 4 1 0 4 4 3 0 AAA domain DUF87 PF01935.12 XP_011271332.1 - 0.052 13.3 0.2 0.052 13.3 0.1 2.0 2 0 0 2 2 1 0 Domain of unknown function DUF87 AAA_22 PF13401.1 XP_011271332.1 - 0.06 13.4 6.7 1.7 8.8 0.8 3.5 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.1 XP_011271332.1 - 0.061 12.9 1.4 4.8 6.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain cobW PF02492.14 XP_011271332.1 - 0.088 12.2 2.2 1.2 8.5 0.2 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 XP_011271332.1 - 0.1 13.4 0.1 38 5.1 0.0 3.3 3 0 0 3 3 2 0 AAA domain UPF0079 PF02367.12 XP_011271332.1 - 0.12 12.0 1.2 0.74 9.4 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DUF4013 PF13197.1 XP_011271333.1 - 0.00029 20.2 0.3 0.00029 20.2 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF4013) Tetraspannin PF00335.15 XP_011271333.1 - 0.011 15.0 0.1 0.028 13.6 0.0 1.8 2 0 0 2 2 2 0 Tetraspanin family DUF1129 PF06570.6 XP_011271333.1 - 1.3 8.3 6.4 0.12 11.7 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DUF1523 PF07509.6 XP_011271334.1 - 0.018 14.2 0.1 0.047 12.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1523) ABC_tran PF00005.22 XP_011271335.1 - 6.1e-49 165.8 6.7 1.3e-28 99.9 0.0 3.7 3 1 0 3 3 2 2 ABC transporter ABC_membrane PF00664.18 XP_011271335.1 - 1.8e-45 155.4 50.8 5.1e-29 101.5 16.7 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 XP_011271335.1 - 7.6e-13 48.1 10.1 0.0022 17.2 0.8 4.3 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 XP_011271335.1 - 1.4e-08 34.1 3.1 1.7e-05 24.2 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 XP_011271335.1 - 4.2e-08 33.5 26.7 0.00012 22.1 0.0 6.5 5 2 1 6 6 5 2 AAA domain T2SE PF00437.15 XP_011271335.1 - 1.1e-06 27.7 0.0 0.00013 20.9 0.0 2.7 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_17 PF13207.1 XP_011271335.1 - 1.4e-06 29.1 1.8 0.016 16.0 0.0 3.4 3 1 0 3 3 2 2 AAA domain Miro PF08477.8 XP_011271335.1 - 3.4e-05 24.3 0.4 0.35 11.3 0.0 3.1 2 0 0 2 2 2 2 Miro-like protein AAA_18 PF13238.1 XP_011271335.1 - 4.7e-05 23.7 2.1 0.066 13.5 0.1 3.8 3 0 0 3 3 2 2 AAA domain DUF258 PF03193.11 XP_011271335.1 - 6.4e-05 22.1 1.9 0.043 13.0 0.3 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 XP_011271335.1 - 0.00011 22.5 26.8 0.00012 22.5 6.6 4.6 3 1 1 4 4 4 2 AAA domain MMR_HSR1 PF01926.18 XP_011271335.1 - 0.00011 22.0 1.6 0.38 10.7 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.1 XP_011271335.1 - 0.00014 21.9 2.1 0.3 11.2 0.1 3.2 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 XP_011271335.1 - 0.00016 21.7 0.3 0.0071 16.3 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 XP_011271335.1 - 0.00018 20.9 0.1 0.037 13.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 XP_011271335.1 - 0.00091 18.8 1.2 0.11 12.1 0.0 2.7 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.7 XP_011271335.1 - 0.0024 17.0 0.1 0.14 11.2 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin IstB_IS21 PF01695.12 XP_011271335.1 - 0.0051 16.2 0.1 0.92 8.9 0.0 2.7 2 0 0 2 2 2 1 IstB-like ATP binding protein ATP_bind_1 PF03029.12 XP_011271335.1 - 0.01 15.3 0.8 2.6 7.5 0.1 3.3 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.13 XP_011271335.1 - 0.012 15.0 0.8 5.7 6.3 0.1 3.0 3 0 0 3 3 3 0 FtsK/SpoIIIE family ArgK PF03308.11 XP_011271335.1 - 0.013 14.3 0.7 1.2 7.8 0.1 2.3 2 0 0 2 2 2 0 ArgK protein RNA_helicase PF00910.17 XP_011271335.1 - 0.017 15.2 2.5 2.1 8.5 0.0 3.8 4 0 0 4 4 3 0 RNA helicase Mg_chelatase PF01078.16 XP_011271335.1 - 0.019 14.1 0.3 4.3 6.4 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI MobB PF03205.9 XP_011271335.1 - 0.024 14.3 0.2 5.8 6.6 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PRK PF00485.13 XP_011271335.1 - 0.025 14.1 1.0 6.7 6.2 0.0 2.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_10 PF12846.2 XP_011271335.1 - 0.026 13.9 1.3 1.5 8.1 0.1 2.6 2 0 0 2 2 2 0 AAA-like domain ATP-synt_ab PF00006.20 XP_011271335.1 - 0.04 13.4 1.6 6.5 6.1 0.0 3.0 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_28 PF13521.1 XP_011271335.1 - 0.045 13.7 1.0 0.12 12.3 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 XP_011271335.1 - 0.063 13.0 0.1 0.21 11.3 0.0 1.9 2 0 0 2 2 1 0 Part of AAA domain cobW PF02492.14 XP_011271335.1 - 0.069 12.5 0.9 1 8.7 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 XP_011271335.1 - 0.071 12.7 0.3 0.6 9.7 0.0 2.3 2 0 0 2 2 2 0 NACHT domain AAA_5 PF07728.9 XP_011271335.1 - 0.074 12.7 0.2 1.5 8.5 0.0 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) ABC_membrane PF00664.18 XP_011271336.1 - 3.5e-48 164.3 51.0 6.3e-30 104.5 17.6 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 XP_011271336.1 - 3.9e-48 163.2 1.3 9.4e-29 100.4 0.0 3.4 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.14 XP_011271336.1 - 3.3e-11 42.8 9.6 0.0013 18.0 1.1 4.4 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 XP_011271336.1 - 3.5e-08 32.8 3.0 4.8e-05 22.7 0.3 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 XP_011271336.1 - 3.3e-05 24.3 0.5 3.3e-05 24.3 0.4 3.8 2 1 1 3 3 2 2 AAA domain AAA_25 PF13481.1 XP_011271336.1 - 0.00012 21.5 0.1 0.029 13.7 0.0 2.7 3 0 0 3 3 3 1 AAA domain T2SE PF00437.15 XP_011271336.1 - 0.00025 20.0 0.2 0.0023 16.8 0.1 2.1 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_16 PF13191.1 XP_011271336.1 - 0.00035 20.6 0.5 0.0076 16.2 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.18 XP_011271336.1 - 0.00052 19.9 0.5 0.57 10.1 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_17 PF13207.1 XP_011271336.1 - 0.00071 20.3 5.5 0.12 13.1 0.0 3.4 3 1 0 3 3 2 2 AAA domain Miro PF08477.8 XP_011271336.1 - 0.0022 18.5 1.2 1.7 9.1 0.0 3.2 2 0 0 2 2 2 1 Miro-like protein DUF258 PF03193.11 XP_011271336.1 - 0.0022 17.2 1.5 0.78 8.9 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 XP_011271336.1 - 0.0033 16.5 0.4 0.44 9.5 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin RNA_helicase PF00910.17 XP_011271336.1 - 0.007 16.5 0.6 40 4.4 0.0 4.3 3 1 0 3 3 3 0 RNA helicase AAA_30 PF13604.1 XP_011271336.1 - 0.012 15.2 1.6 0.36 10.3 0.0 2.8 3 0 0 3 3 3 0 AAA domain ArgK PF03308.11 XP_011271336.1 - 0.014 14.2 0.3 1.2 7.8 0.0 2.5 2 0 0 2 2 2 0 ArgK protein AAA_22 PF13401.1 XP_011271336.1 - 0.016 15.3 4.3 2.1 8.4 0.1 3.3 2 1 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 XP_011271336.1 - 0.029 13.9 1.4 0.74 9.3 0.1 2.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein cobW PF02492.14 XP_011271336.1 - 0.032 13.6 1.2 0.28 10.6 0.1 2.6 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.2 XP_011271336.1 - 0.04 13.3 1.4 3.7 6.9 0.1 2.6 2 0 0 2 2 2 0 AAA-like domain AAA_19 PF13245.1 XP_011271336.1 - 0.076 12.7 0.1 0.26 11.0 0.0 1.9 2 0 0 2 2 1 0 Part of AAA domain IstB_IS21 PF01695.12 XP_011271336.1 - 0.079 12.3 0.2 13 5.1 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein Mg_chelatase PF01078.16 XP_011271336.1 - 0.091 11.9 0.5 18 4.3 0.0 3.1 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI FtsK_SpoIIIE PF01580.13 XP_011271336.1 - 0.17 11.3 0.8 2.9 7.3 0.0 2.7 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_18 PF13238.1 XP_011271336.1 - 0.51 10.6 9.5 1.6 9.0 0.1 3.9 4 0 0 4 4 3 0 AAA domain ABC_tran PF00005.22 XP_011271337.1 - 3.8e-49 166.4 1.3 1.5e-29 103.0 0.0 3.1 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 XP_011271337.1 - 1.8e-47 162.0 46.4 2.5e-28 99.2 14.5 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 XP_011271337.1 - 3.9e-10 39.3 9.3 0.00036 19.8 0.5 4.3 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 XP_011271337.1 - 5.3e-08 32.2 2.7 0.00024 20.5 0.8 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 XP_011271337.1 - 6.7e-07 29.5 26.1 2.4e-06 27.7 0.2 6.0 6 2 1 7 7 5 2 AAA domain DUF258 PF03193.11 XP_011271337.1 - 2.6e-05 23.4 2.8 0.058 12.5 1.3 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 XP_011271337.1 - 8.7e-05 22.4 0.1 0.36 10.7 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase T2SE PF00437.15 XP_011271337.1 - 0.00016 20.7 0.3 0.019 13.8 0.5 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein Miro PF08477.8 XP_011271337.1 - 0.00018 21.9 2.2 0.5 10.8 0.1 3.2 2 0 0 2 2 2 2 Miro-like protein AAA_25 PF13481.1 XP_011271337.1 - 0.00041 19.7 0.1 0.21 10.9 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 XP_011271337.1 - 0.00082 20.1 1.5 2.5 8.9 0.0 3.3 2 1 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 XP_011271337.1 - 0.0014 17.8 0.4 0.15 11.1 0.1 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_23 PF13476.1 XP_011271337.1 - 0.0052 17.1 1.4 0.0052 17.1 1.0 4.1 3 2 1 4 4 2 2 AAA domain AAA_16 PF13191.1 XP_011271337.1 - 0.0054 16.7 1.3 0.11 12.5 0.3 2.4 2 0 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.12 XP_011271337.1 - 0.0073 15.7 0.0 1.9 7.8 0.0 2.7 2 0 0 2 2 2 1 IstB-like ATP binding protein ATP-synt_ab PF00006.20 XP_011271337.1 - 0.008 15.6 0.0 4.3 6.7 0.0 2.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_30 PF13604.1 XP_011271337.1 - 0.0083 15.7 2.8 0.37 10.3 0.1 2.8 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.17 XP_011271337.1 - 0.0085 16.2 2.1 1.6 8.9 0.1 3.8 3 1 0 3 3 3 1 RNA helicase ArgK PF03308.11 XP_011271337.1 - 0.01 14.6 0.5 3.1 6.4 0.0 2.3 2 0 0 2 2 2 0 ArgK protein PRK PF00485.13 XP_011271337.1 - 0.013 15.0 0.9 3.1 7.2 0.1 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_22 PF13401.1 XP_011271337.1 - 0.015 15.4 5.2 4.2 7.5 0.3 3.5 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 XP_011271337.1 - 0.018 14.4 0.2 6.8 6.1 0.0 3.2 3 0 0 3 3 3 0 FtsK/SpoIIIE family cobW PF02492.14 XP_011271337.1 - 0.027 13.9 1.0 0.33 10.3 0.2 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 XP_011271337.1 - 0.032 14.5 3.9 3.4 7.9 0.1 3.2 3 0 0 3 3 2 0 AAA domain MobB PF03205.9 XP_011271337.1 - 0.033 13.8 0.2 7 6.3 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 XP_011271337.1 - 0.23 10.9 3.8 3.5 7.1 0.6 2.8 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Chorismate_synt PF01264.16 XP_011271337.1 - 0.33 9.3 0.7 0.52 8.7 0.5 1.2 1 0 0 1 1 1 0 Chorismate synthase Dynamin_N PF00350.18 XP_011271337.1 - 3.7 7.3 8.8 6.4 6.5 1.4 2.9 3 0 0 3 3 3 0 Dynamin family ATP-sulfurylase PF01747.12 XP_011271338.1 - 1.8e-88 295.4 0.1 2.5e-88 294.9 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.1 XP_011271338.1 - 3.3e-53 179.3 0.0 5.5e-53 178.6 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain Biotin_lipoyl PF00364.17 XP_011271339.1 - 1.4e-18 66.2 0.2 3.2e-18 65.1 0.1 1.7 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.12 XP_011271339.1 - 1e-06 28.2 0.0 2.8e-06 26.8 0.0 1.8 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 XP_011271339.1 - 0.014 14.9 0.1 0.15 11.7 0.0 2.5 2 0 0 2 2 2 0 Biotin-lipoyl like Mucin PF01456.12 XP_011271340.1 - 0.025 14.3 18.5 0.049 13.4 12.8 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein NOC3p PF07540.6 XP_011271341.1 - 2.1e-32 111.2 0.4 2.1e-32 111.2 0.3 2.7 2 1 0 2 2 2 1 Nucleolar complex-associated protein CBF PF03914.12 XP_011271341.1 - 3.5e-31 107.8 0.4 3.5e-31 107.8 0.3 2.7 2 1 0 2 2 2 1 CBF/Mak21 family Spc97_Spc98 PF04130.8 XP_011271341.1 - 0.33 9.2 11.9 0.029 12.6 1.7 2.2 2 0 0 2 2 2 0 Spc97 / Spc98 family PAP_central PF04928.12 XP_011271341.1 - 0.39 9.4 8.2 2.5 6.8 1.5 2.4 2 0 0 2 2 2 0 Poly(A) polymerase central domain CDC45 PF02724.9 XP_011271341.1 - 5.8 4.8 20.9 0.17 9.8 7.2 2.3 2 0 0 2 2 2 0 CDC45-like protein Mpp10 PF04006.7 XP_011271342.1 - 3.8e-118 395.4 79.0 4.6e-118 395.1 54.8 1.0 1 0 0 1 1 1 1 Mpp10 protein Aldedh PF00171.17 XP_011271343.1 - 1.2e-130 435.9 0.2 1.4e-130 435.7 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family CodY PF06018.9 XP_011271343.1 - 0.11 11.7 0.1 14 4.8 0.0 2.3 2 0 0 2 2 2 0 CodY GAF-like domain UCH PF00443.24 XP_011271344.1 - 1.5e-59 201.2 3.6 1.5e-59 201.2 2.5 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 XP_011271344.1 - 2.2e-28 99.5 7.5 2.2e-28 99.5 5.2 2.8 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.15 XP_011271344.1 - 0.11 12.8 0.0 0.27 11.5 0.0 1.8 1 0 0 1 1 1 0 Rhodanese-like domain TPP_enzyme_N PF02776.13 XP_011271345.1 - 1.7e-57 193.6 0.2 5.5e-57 192.0 0.1 1.9 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 XP_011271345.1 - 2.9e-50 169.8 0.8 2.8e-48 163.3 0.1 3.5 4 0 0 4 4 4 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 XP_011271345.1 - 5.9e-38 129.7 0.8 3.6e-37 127.1 0.1 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.14 XP_011271345.1 - 0.024 14.1 0.1 0.051 13.0 0.1 1.5 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Methyltransf_23 PF13489.1 XP_011271345.1 - 0.097 12.3 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.20 XP_011271346.1 - 8.4e-77 257.8 0.0 1.8e-76 256.7 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011271346.1 - 3.2e-37 128.0 0.0 7.6e-37 126.7 0.0 1.6 1 1 1 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 XP_011271346.1 - 0.00025 20.1 0.0 0.00081 18.4 0.0 1.7 2 0 0 2 2 2 1 Kinase-like p450 PF00067.17 XP_011271347.1 - 4.1e-102 342.0 0.0 4.7e-102 341.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PPTA PF01239.17 XP_011271349.1 - 0.051 12.9 4.2 0.054 12.8 0.4 2.8 2 0 0 2 2 2 0 Protein prenyltransferase alpha subunit repeat Oxysterol_BP PF01237.13 XP_011271350.1 - 1.6e-94 316.3 0.0 2.1e-94 315.9 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein DUF3074 PF11274.3 XP_011271350.1 - 0.09 12.3 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3074) Dynamin_M PF01031.15 XP_011271351.1 - 1.4e-105 352.3 0.1 2.6e-105 351.4 0.1 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 XP_011271351.1 - 2.7e-55 186.7 0.3 6.1e-55 185.5 0.2 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 XP_011271351.1 - 1.4e-25 89.0 4.6 3.7e-25 87.6 3.2 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 XP_011271351.1 - 0.0002 21.2 0.8 0.0021 17.9 0.6 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 XP_011271351.1 - 0.035 14.6 0.0 0.097 13.1 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein DUF4112 PF13430.1 XP_011271352.1 - 7.9e-33 112.5 0.1 1e-32 112.2 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) AATase PF07247.7 XP_011271353.1 - 1.2e-42 146.0 3.6 1.6e-42 145.6 2.5 1.1 1 0 0 1 1 1 1 Alcohol acetyltransferase Transferase PF02458.10 XP_011271353.1 - 0.0016 16.9 0.1 0.015 13.7 0.0 2.0 1 1 0 1 1 1 1 Transferase family AATase PF07247.7 XP_011271354.1 - 2.3e-53 181.4 3.0 3.1e-53 181.0 2.1 1.1 1 0 0 1 1 1 1 Alcohol acetyltransferase Transferase PF02458.10 XP_011271354.1 - 0.048 12.1 0.0 0.12 10.8 0.0 1.5 1 1 0 1 1 1 0 Transferase family F-box-like PF12937.2 XP_011271355.1 - 0.13 12.0 0.2 0.25 11.0 0.1 1.5 1 0 0 1 1 1 0 F-box-like MFS_1 PF07690.11 XP_011271356.1 - 9.8e-19 67.2 19.5 1.7e-07 30.3 5.2 3.6 2 1 2 4 4 4 3 Major Facilitator Superfamily DUF485 PF04341.7 XP_011271356.1 - 5.2 6.8 7.7 9.3 6.0 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function, DUF485 MFS_1 PF07690.11 XP_011271357.1 - 8e-34 116.8 21.5 8e-34 116.8 14.9 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily HTH_Tnp_1_2 PF13022.1 XP_011271357.1 - 0.087 12.6 0.4 0.16 11.7 0.3 1.4 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase CENP-T PF15511.1 XP_011271358.1 - 1.9e-15 57.0 30.8 4.6e-11 42.6 3.0 2.4 1 1 1 2 2 2 2 Centromere kinetochore component CENP-T DUF1987 PF09345.5 XP_011271358.1 - 0.0036 17.0 1.3 0.0083 15.9 0.6 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF1987) CENP-S PF15630.1 XP_011271358.1 - 0.025 14.7 0.2 0.053 13.7 0.1 1.6 1 0 0 1 1 1 0 Kinetochore component CENP-S GIDA PF01134.17 XP_011271359.1 - 7.2e-158 525.5 0.0 9.7e-158 525.1 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 XP_011271359.1 - 2.2e-16 59.6 0.0 6.8e-16 58.0 0.0 1.8 1 0 0 1 1 1 1 GidA associated domain 3 Pyr_redox_2 PF07992.9 XP_011271359.1 - 2.1e-07 31.0 0.2 5.1e-07 29.7 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 XP_011271359.1 - 0.00036 19.7 0.1 0.00054 19.1 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 XP_011271359.1 - 0.00042 19.3 0.3 0.32 9.8 0.0 2.7 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 XP_011271359.1 - 0.004 16.0 0.8 0.012 14.5 0.2 2.0 3 0 0 3 3 3 1 FAD binding domain HI0933_like PF03486.9 XP_011271359.1 - 0.053 11.9 0.4 3.1 6.1 0.1 2.4 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.22 XP_011271359.1 - 0.07 13.5 0.1 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FHA PF00498.21 XP_011271360.1 - 4e-07 30.0 0.4 8.6e-07 28.9 0.2 1.6 1 0 0 1 1 1 1 FHA domain DUF3403 PF11883.3 XP_011271360.1 - 2.6 8.3 5.0 9.4 6.5 2.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3403) CBFB_NFYA PF02045.10 XP_011271361.1 - 1.2e-28 99.4 8.6 1.2e-28 99.4 6.0 1.7 2 0 0 2 2 2 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B PhyH PF05721.8 XP_011271362.1 - 1.4e-11 44.8 0.0 2.1e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 XP_011271362.1 - 1.7e-07 30.1 0.2 0.027 12.9 0.0 3.0 2 1 0 2 2 2 2 Protein of unknown function (DUF1479) ComJ PF11033.3 XP_011271362.1 - 0.11 12.1 0.1 0.22 11.1 0.1 1.5 1 0 0 1 1 1 0 Competence protein J (ComJ) MFS_1 PF07690.11 XP_011271363.1 - 9e-13 47.6 42.0 8.5e-11 41.1 15.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 XP_011271363.1 - 1.8e-08 33.2 5.5 3.4e-07 29.0 2.0 2.1 1 1 1 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.2 XP_011271363.1 - 0.008 15.9 2.5 0.008 15.9 1.7 2.7 3 1 0 3 3 3 1 MFS_1 like family Humanin PF15040.1 XP_011271363.1 - 0.075 12.2 0.2 0.075 12.2 0.1 1.7 2 0 0 2 2 2 0 Humanin family Dynein_IC2 PF11540.3 XP_011271363.1 - 0.16 11.3 0.3 1 8.7 0.0 2.2 2 0 0 2 2 2 0 Cytoplasmic dynein 1 intermediate chain 2 MFS_1 PF07690.11 XP_011271364.1 - 3.4e-10 39.1 0.2 4e-10 38.9 0.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily LuxQ-periplasm PF09308.5 XP_011271364.1 - 0.011 15.0 0.1 0.027 13.8 0.0 1.6 2 0 0 2 2 2 0 LuxQ, periplasmic Cse1 PF08506.5 XP_011271365.1 - 1.5e-157 523.9 15.8 3e-157 522.9 10.9 1.6 1 0 0 1 1 1 1 Cse1 CAS_CSE1 PF03378.10 XP_011271365.1 - 2.1e-116 388.7 13.7 4.6e-116 387.6 9.5 1.6 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus IBN_N PF03810.14 XP_011271365.1 - 3.2e-13 49.3 2.6 1.6e-12 47.1 0.1 3.4 4 0 0 4 4 4 1 Importin-beta N-terminal domain Xpo1 PF08389.7 XP_011271365.1 - 0.0097 15.8 0.1 0.0097 15.8 0.1 4.4 4 1 1 5 5 5 1 Exportin 1-like protein Pico_P2B PF01552.12 XP_011271365.1 - 0.11 12.6 0.7 0.84 9.8 0.3 2.7 2 0 0 2 2 2 0 Picornavirus 2B protein APC10 PF03256.11 XP_011271366.1 - 3.5e-56 189.8 0.1 4.1e-56 189.6 0.1 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.20 XP_011271366.1 - 5e-05 23.1 0.1 0.00011 22.0 0.1 1.7 1 1 0 1 1 1 1 F5/8 type C domain QRPTase_C PF01729.14 XP_011271367.1 - 8.7e-56 188.0 0.0 1.1e-55 187.7 0.0 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 XP_011271367.1 - 2.4e-25 88.1 0.0 5.9e-25 86.9 0.0 1.7 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain UbiD PF01977.11 XP_011271368.1 - 1.3e-123 412.4 0.0 1.5e-123 412.2 0.0 1.0 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase Flavoprotein PF02441.14 XP_011271369.1 - 2.2e-25 88.8 0.1 3.4e-25 88.1 0.1 1.3 1 0 0 1 1 1 1 Flavoprotein Acetyltransf_13 PF13880.1 XP_011271370.1 - 3.2e-18 65.2 0.0 7e-18 64.1 0.0 1.5 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.1 XP_011271370.1 - 1.9e-09 36.8 5.0 4.8e-09 35.6 3.5 1.7 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_1 PF00583.19 XP_011271370.1 - 0.0016 18.4 0.0 0.003 17.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 XP_011271370.1 - 0.0037 17.3 0.2 0.015 15.4 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain GATase_2 PF00310.16 XP_011271371.1 - 2.9e-26 92.0 0.0 2.1e-20 72.7 0.0 2.2 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 XP_011271371.1 - 1.8e-16 60.2 0.0 9.9e-16 57.9 0.0 2.1 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.1 XP_011271371.1 - 7.8e-14 51.4 0.0 2.2e-13 50.0 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 XP_011271371.1 - 7e-10 38.7 0.1 1.3e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.1 XP_011271371.1 - 0.00075 18.2 0.0 0.0014 17.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Multi_ubiq PF14452.1 XP_011271371.1 - 0.012 15.5 0.0 0.028 14.3 0.0 1.6 1 0 0 1 1 1 0 Multiubiquitin DNA_photolyase PF00875.13 XP_011271371.1 - 0.06 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 DNA photolyase DLIC PF05783.6 XP_011271372.1 - 3.2e-12 45.8 4.3 7.6e-06 24.8 0.1 2.3 1 1 1 2 2 2 2 Dynein light intermediate chain (DLIC) DUF3713 PF12506.3 XP_011271372.1 - 0.13 12.3 3.2 2 8.4 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3713) RNase_T PF00929.19 XP_011271373.1 - 4.2e-23 82.4 0.1 1.3e-22 80.8 0.1 1.9 1 0 0 1 1 1 1 Exonuclease Rtt102p PF09510.5 XP_011271374.1 - 3.7e-19 68.9 7.4 3.7e-19 68.9 5.2 3.8 2 2 0 2 2 2 1 Rtt102p-like transcription regulator protein DUF3591 PF12157.3 XP_011271375.1 - 2.7e-171 569.9 7.1 2.7e-171 569.9 4.9 3.0 3 1 0 3 3 3 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.1 XP_011271375.1 - 8.3e-08 31.7 0.9 1.6e-07 30.8 0.6 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 XP_011271375.1 - 0.22 11.5 3.7 0.094 12.6 0.9 1.7 2 0 0 2 2 2 0 Zinc knuckle Peptidase_S10 PF00450.17 XP_011271377.1 - 2.4e-133 445.2 1.0 3.5e-133 444.7 0.7 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.6 XP_011271377.1 - 3.9e-22 78.5 1.0 6.7e-22 77.7 0.7 1.4 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide Abhydrolase_6 PF12697.2 XP_011271377.1 - 0.013 15.3 0.0 0.094 12.5 0.0 2.1 1 1 0 1 1 1 0 Alpha/beta hydrolase family Amidase PF01425.16 XP_011271378.1 - 7.1e-76 255.8 0.0 8.5e-76 255.5 0.0 1.1 1 0 0 1 1 1 1 Amidase Pro_isomerase PF00160.16 XP_011271379.1 - 0.0087 16.2 0.0 0.013 15.6 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD LMBR1 PF04791.11 XP_011271380.1 - 5.4e-30 104.3 27.5 1.5e-29 102.9 19.1 1.7 1 1 0 1 1 1 1 LMBR1-like membrane protein DUF3128 PF11326.3 XP_011271380.1 - 0.08 13.0 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3128) BCDHK_Adom3 PF10436.4 XP_011271381.1 - 1.8e-63 212.9 0.1 2.5e-63 212.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 XP_011271381.1 - 3.3e-17 62.1 0.0 5.9e-17 61.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 XP_011271381.1 - 0.011 15.4 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Med12 PF09497.5 XP_011271382.1 - 2.5e-28 97.8 0.5 8.7e-28 96.0 0.3 2.1 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Spore_II_R PF09551.5 XP_011271382.1 - 0.078 13.0 4.5 0.4 10.7 1.2 3.2 2 0 0 2 2 2 0 Stage II sporulation protein R (spore_II_R) Cation_efflux PF01545.16 XP_011271383.1 - 2.4e-20 72.7 15.8 3.3e-20 72.3 11.0 1.2 1 0 0 1 1 1 1 Cation efflux family Kelch_4 PF13418.1 XP_011271384.1 - 6.1e-09 35.5 0.7 0.00022 20.8 0.0 4.4 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_3 PF13415.1 XP_011271384.1 - 1e-06 28.7 0.7 0.084 13.0 0.2 4.8 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.1 XP_011271384.1 - 9.8e-06 25.5 2.2 0.083 13.0 0.0 5.2 5 1 0 5 5 5 1 Kelch motif Kelch_5 PF13854.1 XP_011271384.1 - 5.3e-05 23.0 0.0 0.0024 17.8 0.0 3.1 3 0 0 3 3 3 1 Kelch motif Kelch_1 PF01344.20 XP_011271384.1 - 0.00011 21.6 0.2 0.56 9.7 0.0 4.7 5 0 0 5 5 5 1 Kelch motif Kelch_2 PF07646.10 XP_011271384.1 - 0.067 12.9 0.2 1.7 8.5 0.0 3.2 3 0 0 3 3 3 0 Kelch motif KilA-N PF04383.8 XP_011271385.1 - 0.00047 19.7 0.0 0.0086 15.6 0.0 2.4 1 1 0 1 1 1 1 KilA-N domain DUF3554 PF12074.3 XP_011271386.1 - 2.4e-55 188.3 14.7 2.4e-55 188.3 10.2 6.3 6 2 1 7 7 7 1 Domain of unknown function (DUF3554) HEAT_2 PF13646.1 XP_011271386.1 - 2.4e-34 117.4 37.2 3.8e-08 33.4 0.0 15.4 13 4 6 19 19 19 10 HEAT repeats HEAT PF02985.17 XP_011271386.1 - 1.7e-30 102.2 13.3 0.052 13.6 0.0 17.3 19 0 0 19 19 19 8 HEAT repeat HEAT_EZ PF13513.1 XP_011271386.1 - 2.3e-25 88.3 37.1 0.0047 17.3 0.1 18.0 15 6 10 25 25 25 10 HEAT-like repeat CLASP_N PF12348.3 XP_011271386.1 - 1.6e-20 73.4 0.3 0.00016 21.1 0.0 6.9 4 1 3 8 8 8 5 CLASP N terminal Adaptin_N PF01602.15 XP_011271386.1 - 1e-15 57.0 11.6 0.15 10.3 0.1 10.8 9 1 2 11 11 11 8 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 XP_011271386.1 - 3.2e-13 49.8 0.0 0.067 13.5 0.0 10.3 10 1 2 12 12 12 2 Vacuolar 14 Fab1-binding region Cohesin_HEAT PF12765.2 XP_011271386.1 - 3.1e-05 23.8 0.2 0.0065 16.3 0.0 4.8 5 0 0 5 5 5 1 HEAT repeat associated with sister chromatid cohesion D-ser_dehydrat PF14031.1 XP_011271387.1 - 1.9e-21 76.0 0.0 5.3e-21 74.6 0.0 1.8 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 XP_011271387.1 - 6.2e-12 45.5 0.0 9.5e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Zn_clus PF00172.13 XP_011271388.1 - 1.2e-11 44.2 8.8 2.4e-11 43.3 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 XP_011271388.1 - 2.1e-09 36.6 8.4 2.1e-09 36.6 5.8 2.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF3987 PF13148.1 XP_011271388.1 - 0.21 10.0 7.9 0.49 8.8 5.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Yip1 PF04893.12 XP_011271389.1 - 5.2e-13 48.8 16.2 7.6e-13 48.3 11.2 1.2 1 0 0 1 1 1 1 Yip1 domain YIF1 PF03878.10 XP_011271389.1 - 0.0093 15.1 2.1 0.014 14.5 1.5 1.2 1 0 0 1 1 1 1 YIF1 Cyto_ox_2 PF02322.10 XP_011271390.1 - 4.4 6.3 0.8 9.7 5.2 0.0 2.0 2 1 0 2 2 2 0 Cytochrome oxidase subunit II Glyco_hydro_92 PF07971.7 XP_011271391.1 - 1.4e-159 531.9 4.8 1.8e-159 531.6 3.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 WD40 PF00400.27 XP_011271392.1 - 6.8e-18 63.8 26.1 2.6e-06 27.1 0.2 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat RWD PF05773.17 XP_011271392.1 - 6.3e-07 29.2 0.7 1.7e-06 27.9 0.1 2.0 2 0 0 2 2 2 1 RWD domain zf-C3HC4_2 PF13923.1 XP_011271392.1 - 0.0006 19.7 9.4 0.0017 18.3 6.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 XP_011271392.1 - 0.00077 19.2 9.9 0.0019 17.9 6.9 1.7 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 XP_011271392.1 - 0.0051 16.8 5.4 0.014 15.5 3.7 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger C1_3 PF07649.7 XP_011271392.1 - 0.17 11.9 8.6 0.53 10.3 5.9 1.9 1 0 0 1 1 1 0 C1-like domain OrfB_Zn_ribbon PF07282.6 XP_011271392.1 - 0.2 11.3 5.7 0.54 9.9 3.9 1.7 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-C3HC4_3 PF13920.1 XP_011271392.1 - 0.31 10.7 14.6 0.7 9.6 10.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 XP_011271392.1 - 0.56 9.9 9.5 1.5 8.5 6.6 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) tRNA_int_endo PF01974.12 XP_011271393.1 - 6.3e-22 77.1 0.1 1.2e-21 76.2 0.1 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 XP_011271393.1 - 3.5e-05 23.2 0.0 0.26 10.8 0.0 2.5 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain DNA_topoisoIV PF00521.15 XP_011271393.1 - 0.087 11.6 1.6 0.48 9.2 1.1 2.0 1 1 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A CDC45 PF02724.9 XP_011271395.1 - 2e-211 703.2 4.0 2.3e-211 703.1 2.8 1.0 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.7 XP_011271395.1 - 4.3e-05 21.6 22.4 6.9e-05 20.9 15.5 1.2 1 0 0 1 1 1 1 Nop14-like family Vfa1 PF08432.5 XP_011271395.1 - 0.084 12.8 14.3 0.19 11.7 9.9 1.6 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SDA1 PF05285.7 XP_011271395.1 - 0.19 10.9 26.6 0.36 10.0 18.5 1.3 1 0 0 1 1 1 0 SDA1 Daxx PF03344.10 XP_011271395.1 - 0.65 8.4 23.8 0.93 7.8 16.5 1.1 1 0 0 1 1 1 0 Daxx Family Zip PF02535.17 XP_011271395.1 - 0.65 8.9 2.6 0.97 8.3 1.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter YL1 PF05764.8 XP_011271395.1 - 1.8 8.1 27.9 3.2 7.2 19.4 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Nop53 PF07767.6 XP_011271395.1 - 1.9 7.3 21.7 3 6.7 15.0 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF1510 PF07423.6 XP_011271395.1 - 4 6.7 24.1 7 5.9 16.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Sporozoite_P67 PF05642.6 XP_011271395.1 - 5.7 4.6 14.6 8.6 4.0 10.1 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen EutQ PF06249.7 XP_011271396.1 - 0.0024 17.4 0.0 0.0024 17.4 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.7 XP_011271396.1 - 0.0057 16.0 0.0 0.0084 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Fer4_14 PF13394.1 XP_011271396.1 - 0.012 15.6 0.0 0.014 15.4 0.0 1.1 1 0 0 1 1 1 0 4Fe-4S single cluster domain Cupin_3 PF05899.7 XP_011271397.1 - 5.5e-07 28.8 0.4 7.6e-07 28.4 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) EutQ PF06249.7 XP_011271397.1 - 2e-06 27.3 0.0 2.3e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_2 PF07883.6 XP_011271397.1 - 0.00018 20.9 0.1 0.00026 20.4 0.1 1.4 1 1 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 XP_011271397.1 - 0.04 13.5 0.0 0.062 12.9 0.0 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain Pirin PF02678.11 XP_011271397.1 - 0.094 12.6 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Pirin Cupin_6 PF12852.2 XP_011271397.1 - 0.13 11.8 0.0 0.17 11.5 0.0 1.1 1 0 0 1 1 1 0 Cupin HR1 PF02185.11 XP_011271398.1 - 0.0015 18.1 4.8 0.0015 18.1 3.3 4.4 1 1 4 5 5 5 1 Hr1 repeat DivIC PF04977.10 XP_011271398.1 - 0.0041 16.5 6.0 0.0041 16.5 4.1 5.3 1 1 3 5 5 5 3 Septum formation initiator IncA PF04156.9 XP_011271398.1 - 0.017 14.7 52.4 0.023 14.3 14.2 3.1 1 1 2 3 3 3 0 IncA protein Reo_sigmaC PF04582.7 XP_011271398.1 - 0.023 13.8 16.2 0.38 9.8 3.7 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Filament PF00038.16 XP_011271398.1 - 0.92 8.9 42.1 1.1 8.6 7.1 2.8 1 1 1 2 2 2 0 Intermediate filament protein PHD PF00628.24 XP_011271399.1 - 0.00021 20.9 7.7 0.00043 19.9 5.3 1.6 1 0 0 1 1 1 1 PHD-finger Peptidase_S46 PF10459.4 XP_011271399.1 - 0.0024 16.3 2.9 0.0024 16.3 2.0 2.2 2 0 0 2 2 2 1 Peptidase S46 Pkinase PF00069.20 XP_011271400.1 - 1.2e-69 234.3 0.1 1.2e-69 234.3 0.1 2.9 3 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011271400.1 - 1.3e-37 129.3 0.0 1.7e-36 125.6 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 XP_011271400.1 - 5.2e-17 61.0 0.0 8.6e-17 60.3 0.0 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.9 XP_011271400.1 - 2.7e-05 23.3 0.0 5.1e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 XP_011271400.1 - 3.4e-05 22.9 0.0 7e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like WaaY PF06176.6 XP_011271400.1 - 0.013 14.6 1.0 0.022 13.9 0.7 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Seadorna_VP7 PF07387.6 XP_011271400.1 - 0.14 10.9 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 YrbL-PhoP_reg PF10707.4 XP_011271400.1 - 0.44 9.8 0.0 0.44 9.8 0.0 2.3 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL APH PF01636.18 XP_011271400.1 - 8 6.1 12.1 91 2.6 8.4 2.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family HLH PF00010.21 XP_011271401.1 - 2.6e-07 30.2 1.0 7.6e-07 28.7 0.4 2.1 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain TraG-D_C PF12696.2 XP_011271401.1 - 0.75 9.6 6.5 0.83 9.5 1.1 2.7 2 0 0 2 2 2 0 TraM recognition site of TraD and TraG MSP7_C PF12948.2 XP_011271401.1 - 3.3 7.9 10.0 9.8 6.4 2.0 2.7 2 1 0 2 2 2 0 MSP7-like protein C-terminal domain MamL-1 PF09596.5 XP_011271403.1 - 3.2 7.6 7.4 0.58 10.0 0.8 2.2 2 0 0 2 2 2 0 MamL-1 domain DUF1660 PF07874.6 XP_011271403.1 - 5.6 7.3 9.4 12 6.2 0.7 3.0 3 0 0 3 3 3 0 Prophage protein (DUF1660) Aha1_N PF09229.6 XP_011271404.1 - 3.9e-36 123.8 2.5 7.7e-36 122.9 1.8 1.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 XP_011271404.1 - 1.1e-10 41.6 0.0 1.9e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Pox_A12 PF04651.8 XP_011271404.1 - 0.078 13.0 5.7 0.14 12.2 4.0 1.4 1 0 0 1 1 1 0 Poxvirus A12 protein GST_N_3 PF13417.1 XP_011271405.1 - 2.9e-15 56.2 0.0 4.4e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 XP_011271405.1 - 1.9e-13 50.1 0.0 3.4e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 XP_011271405.1 - 2.7e-11 43.4 0.0 4.5e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 XP_011271405.1 - 2.1e-10 40.4 0.3 5.1e-10 39.2 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 XP_011271405.1 - 1.6e-05 24.7 0.0 3.3e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 XP_011271405.1 - 0.00048 20.5 0.0 0.001 19.5 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MFS_1 PF07690.11 XP_011271406.1 - 1.3e-30 106.2 37.0 1.3e-30 106.2 25.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 XP_011271406.1 - 2.9e-05 22.4 4.9 2.9e-05 22.4 3.4 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Fungal_trans_2 PF11951.3 XP_011271407.1 - 3.6e-13 48.8 0.2 3.6e-13 48.8 0.1 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 XP_011271407.1 - 5e-09 35.9 10.4 7.8e-09 35.2 7.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HrpJ PF07201.6 XP_011271407.1 - 0.27 11.2 7.8 0.26 11.2 4.4 1.7 2 0 0 2 2 2 0 HrpJ-like domain Lin-8 PF03353.10 XP_011271407.1 - 0.57 9.4 14.6 1.1 8.4 10.1 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Cpn60_TCP1 PF00118.19 XP_011271408.1 - 4.4e-145 484.0 15.9 5e-145 483.8 11.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Ras PF00071.17 XP_011271409.1 - 5.7e-44 149.3 0.0 7.1e-44 149.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 XP_011271409.1 - 1.5e-09 38.3 0.0 2.1e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein HATPase_c PF02518.21 XP_011271410.1 - 1.7e-28 98.5 0.5 5.6e-28 96.8 0.3 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 XP_011271410.1 - 4.3e-19 68.5 0.1 1e-18 67.3 0.1 1.7 1 0 0 1 1 1 1 Response regulator receiver domain AAA_16 PF13191.1 XP_011271410.1 - 1.4e-17 64.2 0.0 2.8e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Pkinase PF00069.20 XP_011271410.1 - 7.8e-15 54.7 0.0 1.7e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain HisKA PF00512.20 XP_011271410.1 - 1.3e-14 53.8 0.0 6.3e-14 51.7 0.0 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF_3 PF13492.1 XP_011271410.1 - 3.6e-11 43.2 0.0 7.6e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 GAF domain GAF PF01590.21 XP_011271410.1 - 1.4e-09 38.2 0.0 2.9e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.1 XP_011271410.1 - 5.5e-08 33.4 0.0 1.3e-07 32.1 0.0 1.7 1 0 0 1 1 1 1 GAF domain Pkinase_Tyr PF07714.12 XP_011271410.1 - 1.7e-05 24.0 0.0 3.3e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HATPase_c_3 PF13589.1 XP_011271410.1 - 0.0014 18.2 0.6 0.0031 17.1 0.4 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Sigma54_activat PF00158.21 XP_011271410.1 - 0.019 14.4 0.0 0.035 13.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain W2 PF02020.13 XP_011271411.1 - 2.6e-13 49.7 9.8 2.6e-13 49.7 6.8 3.0 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.19 XP_011271411.1 - 2.1e-11 42.7 20.4 0.00088 18.6 0.8 4.8 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.18 XP_011271411.1 - 3.8e-08 32.9 0.0 1.1e-07 31.4 0.0 1.9 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 XP_011271411.1 - 0.0023 18.0 0.0 0.0048 16.9 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 XP_011271411.1 - 0.017 14.6 16.5 0.23 11.0 5.2 3.5 2 2 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase AAA PF00004.24 XP_011271412.1 - 8.7e-44 148.9 0.0 1.6e-43 148.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 XP_011271412.1 - 6.2e-08 32.4 0.0 1.9e-07 30.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 XP_011271412.1 - 2.6e-07 30.7 0.0 4.6e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 XP_011271412.1 - 1.7e-06 28.2 0.2 0.00011 22.3 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 XP_011271412.1 - 7.9e-06 25.9 0.0 3.1e-05 24.0 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 XP_011271412.1 - 0.00011 23.0 0.0 0.0003 21.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 XP_011271412.1 - 0.00012 21.8 0.1 0.00027 20.6 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 XP_011271412.1 - 0.00015 20.8 0.0 0.00026 20.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 XP_011271412.1 - 0.00022 20.6 0.0 0.00039 19.8 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 XP_011271412.1 - 0.00074 19.4 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 XP_011271412.1 - 0.0013 18.6 0.0 0.0026 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 XP_011271412.1 - 0.0018 18.2 0.0 0.0036 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 XP_011271412.1 - 0.002 18.4 0.1 0.018 15.3 0.0 2.5 3 0 0 3 3 2 1 AAA domain TIP49 PF06068.8 XP_011271412.1 - 0.0023 16.7 0.1 0.007 15.1 0.0 1.9 2 0 0 2 2 2 1 TIP49 C-terminus Zeta_toxin PF06414.7 XP_011271412.1 - 0.0029 16.7 0.0 0.0055 15.8 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_3 PF07726.6 XP_011271412.1 - 0.0069 15.9 0.0 0.019 14.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 XP_011271412.1 - 0.01 14.9 0.0 0.023 13.8 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PhoH PF02562.11 XP_011271412.1 - 0.013 14.7 0.0 0.041 13.1 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein RNA_helicase PF00910.17 XP_011271412.1 - 0.017 15.2 0.0 0.037 14.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.1 XP_011271412.1 - 0.018 14.4 0.1 0.12 11.7 0.0 2.1 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 XP_011271412.1 - 0.035 13.6 0.0 0.065 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 XP_011271412.1 - 0.044 13.2 0.2 0.24 10.8 0.0 2.2 2 1 0 2 2 2 0 Sigma-54 interaction domain NB-ARC PF00931.17 XP_011271412.1 - 0.046 12.5 0.0 0.09 11.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.7 XP_011271412.1 - 0.071 12.7 0.0 0.31 10.7 0.0 1.9 1 1 1 2 2 2 0 NACHT domain NTPase_1 PF03266.10 XP_011271412.1 - 0.076 12.7 0.3 0.29 10.8 0.0 2.2 2 1 0 2 2 2 0 NTPase Histone PF00125.19 XP_011271412.1 - 0.084 13.0 0.1 0.33 11.1 0.0 2.1 2 0 0 2 2 1 0 Core histone H2A/H2B/H3/H4 DUF815 PF05673.8 XP_011271412.1 - 0.097 11.5 0.0 0.16 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Parvo_NS1 PF01057.12 XP_011271412.1 - 0.1 11.4 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.1 XP_011271412.1 - 0.11 12.5 0.0 0.32 11.0 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain DivIC PF04977.10 XP_011271412.1 - 0.14 11.6 1.3 0.37 10.3 0.9 1.6 1 0 0 1 1 1 0 Septum formation initiator MIF4G PF02854.14 XP_011271413.1 - 2.8e-40 137.9 0.1 5.3e-40 137.0 0.0 1.5 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 XP_011271413.1 - 2.1e-13 49.9 1.2 1.3e-12 47.4 0.8 2.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 Glyco_tran_28_C PF04101.11 XP_011271415.1 - 1.2e-23 83.6 0.1 1.7e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 XP_011271415.1 - 0.00055 19.2 0.0 0.00077 18.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 1 CDK2AP PF09806.4 XP_011271416.1 - 0.28 11.4 8.1 0.78 9.9 1.8 2.2 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein GATase_4 PF13230.1 XP_011271417.1 - 7.2e-18 64.2 0.0 2.2e-17 62.6 0.0 1.7 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 XP_011271417.1 - 6e-11 42.4 0.0 9.8e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 XP_011271417.1 - 3.2e-08 32.6 0.0 4.2e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II vWA-TerF-like PF10138.4 XP_011271417.1 - 0.029 14.1 0.0 0.055 13.2 0.0 1.4 1 1 0 1 1 1 0 vWA found in TerF C terminus Tim17 PF02466.14 XP_011271418.1 - 3.1e-23 82.2 0.5 5.3e-23 81.4 0.4 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DLH PF01738.13 XP_011271418.1 - 0.005 16.1 0.1 0.0071 15.6 0.1 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Arm PF00514.18 XP_011271420.1 - 9.6e-86 279.0 16.1 3.9e-13 48.6 0.0 9.0 10 0 0 10 10 10 8 Armadillo/beta-catenin-like repeat IBB PF01749.15 XP_011271420.1 - 8.2e-24 83.6 9.1 1.7e-23 82.5 6.3 1.5 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.1 XP_011271420.1 - 2.3e-20 72.4 0.3 6.7e-05 23.2 0.0 5.5 4 1 1 5 5 5 3 HEAT-like repeat HEAT_2 PF13646.1 XP_011271420.1 - 3e-20 72.2 0.4 1.5e-06 28.3 0.0 5.2 1 1 4 5 5 5 4 HEAT repeats HEAT PF02985.17 XP_011271420.1 - 2.1e-14 52.2 0.1 0.017 15.1 0.0 6.6 7 0 0 7 7 7 3 HEAT repeat Arm_2 PF04826.8 XP_011271420.1 - 1.8e-05 23.9 0.6 0.12 11.4 0.0 3.7 3 1 1 4 4 4 2 Armadillo-like Proteasom_PSMB PF10508.4 XP_011271420.1 - 5.5e-05 21.6 1.5 0.00015 20.1 0.0 2.3 3 0 0 3 3 3 1 Proteasome non-ATPase 26S subunit RICTOR_V PF14668.1 XP_011271420.1 - 0.00045 20.0 5.8 1 9.3 0.1 5.2 3 2 4 7 7 7 2 Rapamycin-insensitive companion of mTOR, domain 5 V-ATPase_H_C PF11698.3 XP_011271420.1 - 0.00058 19.7 0.0 1.8 8.5 0.0 3.9 2 1 1 4 4 4 2 V-ATPase subunit H Adaptin_N PF01602.15 XP_011271420.1 - 0.0031 15.9 0.7 0.76 8.0 0.1 2.9 1 1 1 2 2 2 2 Adaptin N terminal region DUF2505 PF10698.4 XP_011271420.1 - 0.029 13.8 0.0 3.3 7.2 0.0 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF2505) DUF3552 PF12072.3 XP_011271420.1 - 1.1 8.4 6.8 2.3 7.3 4.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF1882 PF08966.6 XP_011271421.1 - 0.11 12.4 0.0 0.32 10.9 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1882) DUF2414 PF10309.4 XP_011271422.1 - 0.0035 16.9 0.6 0.018 14.6 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2414) DUF2613 PF11021.3 XP_011271423.1 - 0.13 12.0 6.0 0.15 11.7 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) Hid1 PF12722.2 XP_011271423.1 - 8.7 3.8 10.0 11 3.5 7.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MARVEL PF01284.18 XP_011271424.1 - 5.2e-15 55.5 8.0 6.8e-15 55.1 5.5 1.1 1 0 0 1 1 1 1 Membrane-associating domain Choline_transpo PF04515.7 XP_011271424.1 - 0.00083 18.1 2.4 0.016 13.9 0.1 2.1 1 1 1 2 2 2 2 Plasma-membrane choline transporter Mtp PF03821.11 XP_011271424.1 - 0.058 12.7 3.8 0.056 12.8 1.5 1.6 1 1 1 2 2 2 0 Golgi 4-transmembrane spanning transporter DUF588 PF04535.7 XP_011271424.1 - 0.1 12.1 3.2 1.5 8.4 1.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF588) MARVEL PF01284.18 XP_011271425.1 - 1.3e-22 80.1 19.8 1.8e-22 79.7 13.7 1.1 1 0 0 1 1 1 1 Membrane-associating domain Tic20 PF09685.5 XP_011271425.1 - 3 7.8 15.1 0.83 9.6 6.1 2.1 2 0 0 2 2 2 0 Tic20-like protein Ras PF00071.17 XP_011271426.1 - 7.4e-46 155.4 0.3 1.2e-45 154.8 0.2 1.3 1 0 0 1 1 1 1 Ras family Oxidored_q6 PF01058.17 XP_011271426.1 - 5.3e-21 74.6 0.1 1.3e-20 73.3 0.1 1.7 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Kelch_4 PF13418.1 XP_011271426.1 - 1.6e-15 56.5 11.8 2.9e-05 23.7 0.6 6.6 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_6 PF13964.1 XP_011271426.1 - 1.5e-12 47.1 8.7 0.05 13.7 0.1 7.0 8 0 0 8 8 6 3 Kelch motif Kelch_5 PF13854.1 XP_011271426.1 - 1.4e-11 44.0 7.4 0.32 10.9 0.0 7.6 7 0 0 7 7 7 3 Kelch motif Kelch_1 PF01344.20 XP_011271426.1 - 1.8e-11 43.3 10.6 0.013 15.0 0.3 6.4 6 1 0 6 6 6 3 Kelch motif Kelch_2 PF07646.10 XP_011271426.1 - 2.2e-11 43.0 8.5 0.014 15.1 0.0 6.8 7 1 0 7 7 7 3 Kelch motif Miro PF08477.8 XP_011271426.1 - 4.2e-11 43.3 0.1 1.5e-10 41.5 0.1 2.1 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 XP_011271426.1 - 4.3e-07 29.3 0.3 8.1e-07 28.4 0.2 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Kelch_3 PF13415.1 XP_011271426.1 - 3.4e-06 27.0 2.9 0.027 14.6 0.0 6.4 9 0 0 9 9 8 1 Galactose oxidase, central domain GTP_EFTU PF00009.22 XP_011271426.1 - 0.013 14.9 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Glyco_tran_28_C PF04101.11 XP_011271426.1 - 0.019 14.6 0.0 0.053 13.1 0.0 1.7 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain AATase PF07247.7 XP_011271427.1 - 7.7e-22 77.4 12.9 1.8e-20 72.9 8.9 2.5 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 XP_011271427.1 - 0.0097 14.7 0.5 0.015 14.1 0.1 1.4 2 0 0 2 2 2 1 Condensation domain AATase PF07247.7 XP_011271428.1 - 1.1e-25 90.1 0.4 2.4e-25 89.0 0.3 1.4 1 1 0 1 1 1 1 Alcohol acetyltransferase Aminotran_3 PF00202.16 XP_011271429.1 - 9.5e-92 307.4 0.0 1.1e-91 307.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 XP_011271429.1 - 0.0074 15.4 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 XP_011271429.1 - 0.097 11.6 0.0 0.15 10.9 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II PhyH PF05721.8 XP_011271430.1 - 5.1e-23 82.2 0.0 6.8e-23 81.8 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 XP_011271430.1 - 0.086 11.3 0.2 0.17 10.3 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1479) AAA_26 PF13500.1 XP_011271431.1 - 2.1e-47 161.3 0.2 2.4e-47 161.1 0.2 1.0 1 0 0 1 1 1 1 AAA domain CbiA PF01656.18 XP_011271431.1 - 7.2e-06 25.5 2.6 0.016 14.6 0.2 2.1 2 0 0 2 2 2 2 CobQ/CobB/MinD/ParA nucleotide binding domain DUF1611 PF07755.6 XP_011271431.1 - 0.028 13.0 0.1 0.72 8.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1611) Aminotran_3 PF00202.16 XP_011271432.1 - 1.3e-96 323.4 0.0 1.5e-96 323.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 XP_011271432.1 - 0.018 14.2 0.0 0.025 13.7 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Sugar_tr PF00083.19 XP_011271433.1 - 8e-29 100.4 28.8 1.9e-28 99.2 19.9 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 XP_011271433.1 - 2.4e-15 56.1 32.6 1.3e-08 34.0 8.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF569 PF04601.8 XP_011271434.1 - 0.092 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF569) Arrestin_C PF02752.17 XP_011271435.1 - 7.7e-18 64.9 0.2 4.3e-17 62.5 0.0 2.4 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 XP_011271435.1 - 7.5e-08 32.3 0.1 8.9e-06 25.5 0.0 3.2 3 0 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Zn_clus PF00172.13 XP_011271436.1 - 1e-08 34.9 9.4 1.7e-08 34.2 6.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Flavoprotein PF02441.14 XP_011271437.1 - 1.2e-44 151.1 0.2 2.8e-44 149.9 0.1 1.7 1 0 0 1 1 1 1 Flavoprotein Glutaredoxin PF00462.19 XP_011271438.1 - 9.5e-17 60.7 0.0 2.6e-16 59.3 0.0 1.7 2 0 0 2 2 2 1 Glutaredoxin MIF4G_like PF09088.6 XP_011271439.1 - 2.2e-61 206.6 4.8 5.5e-59 198.8 2.2 2.3 2 0 0 2 2 2 2 MIF4G like MIF4G_like_2 PF09090.6 XP_011271439.1 - 6.3e-30 104.2 0.2 1.1e-28 100.1 0.1 2.5 1 1 0 1 1 1 1 MIF4G like MIF4G PF02854.14 XP_011271439.1 - 3.5e-09 36.3 5.1 8.3e-08 31.8 0.1 3.3 3 0 0 3 3 3 2 MIF4G domain Tht1 PF04163.7 XP_011271441.1 - 4.9e-29 101.1 28.5 1.9e-28 99.1 19.6 1.8 1 1 0 1 1 1 1 Tht1-like nuclear fusion protein NAAA-beta PF15508.1 XP_011271441.1 - 0.59 10.5 4.7 3.9 7.8 0.3 3.3 1 1 1 3 3 3 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase DUF1664 PF07889.7 XP_011271441.1 - 2.7 7.7 13.6 6.7 6.5 0.7 3.6 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) Carbpep_Y_N PF05388.6 XP_011271441.1 - 4.9 7.3 9.7 4.3 7.5 0.9 3.2 2 1 1 3 3 3 0 Carboxypeptidase Y pro-peptide FUSC-like PF12805.2 XP_011271441.1 - 5.1 5.9 10.2 4.6 6.0 0.4 3.0 3 1 1 4 4 4 0 FUSC-like inner membrane protein yccS Nsp1_C PF05064.8 XP_011271441.1 - 5.2 6.7 22.5 1.3 8.6 1.8 3.8 4 0 0 4 4 4 0 Nsp1-like C-terminal region TACC PF05010.9 XP_011271441.1 - 9.1 5.9 20.0 1.4 8.6 10.7 2.0 2 1 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC) Choline_kin_N PF04428.9 XP_011271442.1 - 0.066 12.6 3.0 0.43 10.0 0.0 3.1 3 1 1 4 4 4 0 Choline kinase N terminus SUR7 PF06687.7 XP_011271443.1 - 2.4e-27 95.9 11.9 4e-27 95.1 8.2 1.4 1 0 0 1 1 1 1 SUR7/PalI family DUF621 PF04789.10 XP_011271443.1 - 3.1 6.7 6.5 5 6.0 4.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF621) HA2 PF04408.18 XP_011271444.1 - 3.8e-20 71.7 0.2 3.8e-20 71.7 0.1 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 XP_011271444.1 - 1.7e-14 53.6 0.0 3.7e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 XP_011271444.1 - 9.5e-14 51.0 0.0 5.3e-13 48.6 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 XP_011271444.1 - 1.3e-07 31.7 0.2 3e-07 30.6 0.1 1.6 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 XP_011271444.1 - 9.4e-06 25.2 0.3 2.1e-05 24.1 0.2 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_29 PF13555.1 XP_011271444.1 - 0.0023 17.4 0.1 0.0054 16.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Flavi_DEAD PF07652.9 XP_011271444.1 - 0.0098 15.6 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 Flavivirus DEAD domain T2SE PF00437.15 XP_011271444.1 - 0.014 14.3 0.2 0.025 13.4 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF258 PF03193.11 XP_011271444.1 - 0.032 13.4 0.0 0.074 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_19 PF13245.1 XP_011271444.1 - 0.036 13.8 0.1 0.097 12.4 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_16 PF13191.1 XP_011271444.1 - 0.089 12.7 0.1 0.26 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.22 XP_011271444.1 - 0.17 12.2 0.2 0.17 12.2 0.1 2.9 1 1 2 3 3 3 0 ABC transporter Lactamase_B_2 PF12706.2 XP_011271445.1 - 1.2e-33 116.2 0.1 1.6e-33 115.8 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 XP_011271445.1 - 9e-09 35.2 0.0 2e-08 34.1 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Pantoate_transf PF02548.10 XP_011271446.1 - 2.7e-102 341.3 0.0 3.2e-102 341.1 0.0 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 XP_011271446.1 - 1e-08 34.7 0.1 4.6e-08 32.5 0.0 1.9 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Abhydrolase_1 PF00561.15 XP_011271447.1 - 6.9e-13 48.6 0.0 1.5e-12 47.6 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 XP_011271447.1 - 8.8e-12 45.3 0.0 1.4e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 XP_011271447.1 - 0.051 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase Transglut_core PF01841.14 XP_011271448.1 - 2e-13 50.5 0.1 4.7e-13 49.3 0.1 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily Rad4 PF03835.10 XP_011271448.1 - 1.7e-12 46.9 0.5 3.3e-12 46.0 0.3 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain MSA-2c PF12238.3 XP_011271448.1 - 0.0023 17.6 0.1 0.0036 16.9 0.1 1.2 1 0 0 1 1 1 1 Merozoite surface antigen 2c Epimerase PF01370.16 XP_011271449.1 - 6.3e-22 78.1 0.0 8.7e-22 77.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 XP_011271449.1 - 1.2e-19 70.1 0.2 1.6e-19 69.7 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 XP_011271449.1 - 2.3e-12 46.3 0.0 1.7e-11 43.5 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 XP_011271449.1 - 1e-10 41.8 0.0 1.5e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 XP_011271449.1 - 1.4e-06 27.4 0.1 2.4e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 XP_011271449.1 - 7e-06 26.0 0.0 1.1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 XP_011271449.1 - 0.00018 21.2 0.0 0.00035 20.2 0.0 1.4 1 0 0 1 1 1 1 KR domain DapB_N PF01113.15 XP_011271449.1 - 0.00033 20.5 0.0 0.00067 19.5 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.8 XP_011271449.1 - 0.00088 18.5 0.1 0.0019 17.4 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family Shikimate_DH PF01488.15 XP_011271449.1 - 0.003 17.6 0.0 0.0066 16.5 0.0 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.19 XP_011271449.1 - 0.0041 17.4 0.0 0.011 16.0 0.0 1.8 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Sigma54_activ_2 PF14532.1 XP_011271449.1 - 0.015 15.3 0.0 0.051 13.6 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain RmlD_sub_bind PF04321.12 XP_011271449.1 - 0.079 11.8 0.0 0.69 8.7 0.0 2.3 3 0 0 3 3 3 0 RmlD substrate binding domain Epimerase PF01370.16 XP_011271450.1 - 1.6e-21 76.8 0.0 2.4e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 XP_011271450.1 - 3.5e-15 55.4 0.0 4.8e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 XP_011271450.1 - 6.3e-11 41.6 0.1 4.1e-10 39.0 0.1 1.9 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 XP_011271450.1 - 2.8e-08 33.9 0.0 8.2e-08 32.4 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 XP_011271450.1 - 8.4e-06 24.8 0.0 1.2e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 XP_011271450.1 - 8.4e-05 21.9 0.1 0.0023 17.2 0.0 2.3 2 1 0 2 2 2 1 NmrA-like family adh_short PF00106.20 XP_011271450.1 - 0.0052 16.7 0.0 0.0094 15.8 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Semialdhyde_dh PF01118.19 XP_011271450.1 - 0.012 15.8 0.1 0.74 10.1 0.0 2.4 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Sigma54_activ_2 PF14532.1 XP_011271450.1 - 0.044 13.8 0.0 1.8 8.5 0.0 2.8 3 0 0 3 3 3 0 Sigma-54 interaction domain KR PF08659.5 XP_011271450.1 - 0.062 12.9 0.0 0.14 11.7 0.0 1.6 1 1 0 1 1 1 0 KR domain Epimerase PF01370.16 XP_011271451.1 - 5.6e-23 81.6 0.0 7.9e-23 81.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 XP_011271451.1 - 3.3e-15 55.5 0.0 4.5e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 XP_011271451.1 - 1.7e-09 37.0 0.3 2.6e-08 33.0 0.2 2.0 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 XP_011271451.1 - 7.9e-08 32.5 0.0 1.8e-07 31.3 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 XP_011271451.1 - 5.6e-07 28.7 0.0 7.9e-07 28.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 XP_011271451.1 - 0.00016 21.0 0.1 0.0029 16.8 0.0 2.5 2 1 1 3 3 3 1 NmrA-like family KR PF08659.5 XP_011271451.1 - 0.00043 20.0 0.0 0.00072 19.2 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 XP_011271451.1 - 0.0008 19.3 0.0 0.0014 18.6 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Semialdhyde_dh PF01118.19 XP_011271451.1 - 0.028 14.7 0.2 2 8.7 0.0 2.7 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 XP_011271451.1 - 0.081 13.0 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase RmlD_sub_bind PF04321.12 XP_011271451.1 - 0.11 11.3 0.0 0.18 10.6 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain tRNA-synt_1b PF00579.20 XP_011271452.1 - 7.8e-70 235.2 0.0 1.2e-69 234.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Sec62 PF03839.11 XP_011271453.1 - 1.5e-57 194.5 1.3 2.1e-57 194.1 0.9 1.1 1 0 0 1 1 1 1 Translocation protein Sec62 DUF4181 PF13789.1 XP_011271453.1 - 0.02 14.7 0.2 0.045 13.6 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4181) B-block_TFIIIC PF04182.7 XP_011271454.1 - 6.5e-13 48.3 2.1 4.5e-12 45.6 0.0 3.3 4 0 0 4 4 4 1 B-block binding subunit of TFIIIC Romo1 PF10247.4 XP_011271455.1 - 1.6e-26 92.2 10.9 2.2e-26 91.8 7.6 1.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 WD40 PF00400.27 XP_011271456.1 - 0.0021 17.8 0.1 0.3 11.0 0.0 3.5 4 0 0 4 4 4 1 WD domain, G-beta repeat RRM_1 PF00076.17 XP_011271457.1 - 2.5e-34 116.7 0.3 1e-16 60.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 XP_011271457.1 - 1.3e-29 101.9 0.1 1.3e-13 50.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 XP_011271457.1 - 6.3e-13 48.3 0.0 3.3e-06 26.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Vfa1 PF08432.5 XP_011271457.1 - 0.67 9.9 18.8 2 8.4 13.0 1.8 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 TFIIF_alpha PF05793.7 XP_011271457.1 - 2.1 6.6 33.9 3.1 6.0 23.5 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) MGC-24 PF05283.6 XP_011271457.1 - 2.2 8.0 7.4 3.6 7.3 5.1 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Macoilin PF09726.4 XP_011271457.1 - 2.5 6.2 15.0 4 5.5 10.4 1.2 1 0 0 1 1 1 0 Transmembrane protein SAPS PF04499.10 XP_011271457.1 - 6.2 5.3 14.7 9.2 4.7 10.2 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Neur_chan_memb PF02932.11 XP_011271457.1 - 7.2 6.4 10.4 2 8.2 4.7 1.7 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region UPF0020 PF01170.13 XP_011271458.1 - 4.5e-12 45.9 0.0 8.4e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 XP_011271458.1 - 2.5e-06 27.5 0.0 4.9e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.11 XP_011271458.1 - 0.032 13.3 0.0 0.07 12.1 0.0 1.6 1 1 0 1 1 1 0 N-6 DNA Methylase N6_N4_Mtase PF01555.13 XP_011271458.1 - 0.3 10.5 2.3 16 4.8 0.1 3.1 2 2 1 3 3 3 0 DNA methylase Ras PF00071.17 XP_011271459.1 - 6.5e-39 132.9 0.6 9.7e-39 132.3 0.4 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 XP_011271459.1 - 1.8e-17 63.9 0.0 3.3e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 XP_011271459.1 - 1.4e-12 47.2 0.1 1.9e-12 46.7 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 XP_011271459.1 - 6.4e-05 22.2 0.2 0.00011 21.4 0.1 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 XP_011271459.1 - 0.00038 20.4 0.0 0.00066 19.6 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 XP_011271459.1 - 0.0056 16.8 0.0 0.02 15.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 XP_011271459.1 - 0.017 15.1 0.0 0.034 14.1 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain MCM PF00493.18 XP_011271459.1 - 0.018 13.8 0.0 0.029 13.1 0.0 1.4 1 0 0 1 1 1 0 MCM2/3/5 family DUF815 PF05673.8 XP_011271459.1 - 0.046 12.6 0.0 0.07 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF258 PF03193.11 XP_011271459.1 - 0.06 12.5 0.1 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 XP_011271459.1 - 0.12 11.8 0.1 0.27 10.7 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Methyltransf_16 PF10294.4 XP_011271460.1 - 3.7e-31 107.8 0.0 5.7e-31 107.3 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 XP_011271460.1 - 9.4e-08 32.6 0.0 1.7e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 XP_011271460.1 - 0.00013 21.2 0.0 0.00021 20.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 XP_011271460.1 - 0.00021 20.8 0.0 0.00036 20.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 XP_011271460.1 - 0.00029 20.2 0.0 0.00049 19.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 XP_011271460.1 - 0.0003 20.7 0.0 0.0005 20.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 XP_011271460.1 - 0.0038 16.9 0.0 0.0055 16.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 XP_011271460.1 - 0.033 14.6 0.0 0.068 13.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.11 XP_011271460.1 - 0.033 13.7 0.0 0.051 13.1 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein DUF938 PF06080.7 XP_011271460.1 - 0.088 12.3 0.0 0.22 11.0 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF938) Ribosomal_S17 PF00366.15 XP_011271461.1 - 8.8e-11 41.6 1.2 2.1e-10 40.4 0.9 1.7 1 0 0 1 1 1 1 Ribosomal protein S17 Spore_III_AB PF09548.5 XP_011271461.1 - 0.014 15.1 3.2 0.014 15.1 2.2 2.0 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) AAA_assoc_C PF09821.4 XP_011271461.1 - 0.21 11.8 5.3 0.15 12.3 0.8 2.7 1 1 2 3 3 3 0 C-terminal AAA-associated domain Herpes_US9 PF06072.6 XP_011271461.1 - 0.59 10.0 2.2 9.2 6.1 0.1 2.4 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 Med9 PF07544.8 XP_011271461.1 - 0.97 9.2 9.6 0.041 13.5 1.2 2.8 2 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Baculo_PEP_C PF04513.7 XP_011271462.1 - 0.00082 19.2 12.0 0.002 17.9 8.2 1.7 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DASH_Duo1 PF08651.5 XP_011271462.1 - 0.24 10.9 0.9 4.5 6.9 0.0 2.7 3 0 0 3 3 3 0 DASH complex subunit Duo1 DUF948 PF06103.6 XP_011271462.1 - 0.25 11.2 4.8 7.9 6.4 3.2 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) HsbA PF12296.3 XP_011271462.1 - 0.71 9.7 5.0 15 5.4 3.5 2.2 1 1 0 1 1 1 0 Hydrophobic surface binding protein A NPV_P10 PF05531.7 XP_011271462.1 - 1.1 9.5 3.7 39 4.5 0.0 2.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Bac_luciferase PF00296.15 XP_011271463.1 - 0.0025 16.9 0.0 0.0029 16.7 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Bac_luciferase PF00296.15 XP_011271464.1 - 1.9e-42 145.4 0.0 2.4e-42 145.1 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase CPSase_L_chain PF00289.17 XP_011271464.1 - 0.0004 20.4 0.0 0.0095 16.0 0.0 2.5 2 1 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain DUF3252 PF11623.3 XP_011271464.1 - 0.023 14.0 0.1 0.061 12.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3252) TPR_11 PF13414.1 XP_011271465.1 - 7.9e-29 99.1 14.9 2e-12 46.5 0.1 4.4 2 2 2 4 4 4 4 TPR repeat TPR_1 PF00515.23 XP_011271465.1 - 3.2e-23 80.3 2.6 8.1e-08 31.5 0.1 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 XP_011271465.1 - 5.9e-20 69.5 6.8 2e-06 27.2 0.1 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 XP_011271465.1 - 3.6e-16 58.1 2.2 0.00078 19.8 0.1 5.6 3 2 3 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.1 XP_011271465.1 - 9.6e-15 54.6 4.5 0.0027 17.9 0.0 4.7 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.1 XP_011271465.1 - 2.7e-14 52.0 9.3 0.0037 17.3 0.0 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 XP_011271465.1 - 1.5e-13 50.9 2.3 6.3e-06 26.7 0.0 4.3 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_20 PF14561.1 XP_011271465.1 - 2.4e-10 40.3 0.7 0.019 15.0 0.0 4.4 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 XP_011271465.1 - 4.3e-09 36.1 3.6 1.6e-05 24.7 0.0 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 XP_011271465.1 - 5.3e-09 35.2 3.9 0.00086 18.9 0.1 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.1 XP_011271465.1 - 2.1e-06 27.5 0.2 0.031 14.1 0.0 3.6 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 XP_011271465.1 - 3.6e-06 26.3 0.4 0.027 14.2 0.0 4.1 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 XP_011271465.1 - 8.7e-06 25.8 2.3 16 6.2 0.0 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat Apc3 PF12895.2 XP_011271465.1 - 0.00013 21.9 3.5 0.014 15.5 0.2 3.0 2 2 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 XP_011271465.1 - 0.00025 20.2 0.6 0.069 12.1 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat MIT PF04212.13 XP_011271465.1 - 0.0032 17.3 0.0 2 8.3 0.0 3.0 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain BTAD PF03704.12 XP_011271465.1 - 0.068 13.4 0.3 0.32 11.2 0.0 2.2 2 1 0 2 2 2 0 Bacterial transcriptional activator domain DEAD PF00270.24 XP_011271466.1 - 3.1e-44 150.4 0.6 2.8e-41 140.8 0.1 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 XP_011271466.1 - 1e-25 89.3 0.2 2.7e-25 88.0 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 XP_011271466.1 - 3e-05 23.9 0.0 3e-05 23.9 0.0 3.2 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit Peripla_BP_1 PF00532.16 XP_011271466.1 - 0.083 12.0 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Periplasmic binding proteins and sugar binding domain of LacI family Host_attach PF10116.4 XP_011271466.1 - 0.52 10.5 3.6 1 9.5 2.5 1.4 1 0 0 1 1 1 0 Protein required for attachment to host cells RRM_1 PF00076.17 XP_011271467.1 - 3e-10 39.5 0.3 5.6e-10 38.7 0.2 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 XP_011271467.1 - 3.4e-07 30.0 0.8 7.8e-07 28.8 0.6 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 XP_011271467.1 - 0.0017 18.0 0.0 0.0047 16.6 0.0 1.7 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.19 XP_011271467.1 - 0.064 12.9 1.5 0.12 12.1 1.0 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) rRNA_proc-arch PF13234.1 XP_011271470.1 - 1.2e-100 336.1 1.9 1.2e-100 336.1 1.3 1.7 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.7 XP_011271470.1 - 4e-64 215.1 0.7 8.4e-64 214.1 0.5 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 XP_011271470.1 - 1.6e-21 76.5 0.0 9e-21 74.1 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 XP_011271470.1 - 5.2e-07 29.4 0.0 1.8e-06 27.6 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain T2SE PF00437.15 XP_011271470.1 - 0.06 12.2 0.0 0.16 10.8 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein Porphobil_deam PF01379.15 XP_011271471.1 - 1.6e-85 285.3 0.0 2.5e-85 284.7 0.0 1.3 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 XP_011271471.1 - 2.4e-18 66.0 0.0 4.8e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Myb_DNA-binding PF00249.26 XP_011271472.1 - 1.1e-06 28.5 0.0 2.7e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain PH PF00169.24 XP_011271473.1 - 2.9e-14 53.1 0.0 1.2e-13 51.1 0.0 2.1 1 0 0 1 1 1 1 PH domain SH3_9 PF14604.1 XP_011271473.1 - 4.6e-10 38.9 0.0 8.2e-10 38.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 XP_011271473.1 - 1.6e-09 37.0 0.1 2.9e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SAM_2 PF07647.12 XP_011271473.1 - 5.9e-09 35.6 0.0 1e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_11 PF15413.1 XP_011271473.1 - 5.1e-08 33.1 0.0 4.2e-07 30.1 0.0 2.7 2 1 1 3 3 3 1 Pleckstrin homology domain SH3_2 PF07653.12 XP_011271473.1 - 4.2e-05 22.9 0.0 0.00011 21.6 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain PH_8 PF15409.1 XP_011271473.1 - 0.0015 18.5 0.0 0.094 12.7 0.0 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain TPR_19 PF14559.1 XP_011271474.1 - 0.0023 18.2 0.0 2.8 8.3 0.0 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 XP_011271474.1 - 0.0057 16.3 0.3 2.4 8.1 0.0 3.3 2 0 0 2 2 2 2 Tetratricopeptide repeat POTRA_1 PF08478.5 XP_011271474.1 - 0.21 11.6 2.5 9.6 6.3 0.1 2.7 2 0 0 2 2 2 0 POTRA domain, FtsQ-type Aldedh PF00171.17 XP_011271475.1 - 1.9e-172 573.7 0.0 2.2e-172 573.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family COQ9 PF08511.6 XP_011271475.1 - 0.12 11.9 0.0 0.33 10.5 0.0 1.7 1 0 0 1 1 1 0 COQ9 Aminotran_5 PF00266.14 XP_011271476.1 - 5.7e-49 166.8 0.0 7.9e-49 166.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 XP_011271476.1 - 0.035 13.0 0.0 0.17 10.8 0.0 1.9 2 0 0 2 2 2 0 Aminotransferase class I and II Bac_luciferase PF00296.15 XP_011271477.1 - 3.2e-52 177.5 0.0 4.3e-52 177.1 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Choline_kinase PF01633.15 XP_011271478.1 - 0.00012 21.7 1.1 0.00014 21.5 0.7 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 XP_011271478.1 - 0.02 14.6 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.20 XP_011271478.1 - 0.028 13.5 0.1 0.04 13.0 0.0 1.3 1 1 0 1 1 1 0 Protein kinase domain RIO1 PF01163.17 XP_011271478.1 - 0.029 13.7 0.1 0.041 13.2 0.1 1.2 1 0 0 1 1 1 0 RIO1 family cwf21 PF08312.7 XP_011271479.1 - 2.3e-09 36.9 7.8 3.9e-09 36.2 5.4 1.4 1 0 0 1 1 1 1 cwf21 domain SAND PF01342.16 XP_011271479.1 - 0.027 14.1 0.1 0.056 13.1 0.1 1.5 1 0 0 1 1 1 0 SAND domain DUF3926 PF13080.1 XP_011271479.1 - 0.27 10.7 1.2 0.57 9.7 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3926) Zn_clus PF00172.13 XP_011271480.1 - 5.9e-08 32.4 12.6 9.5e-08 31.8 8.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LRR_8 PF13855.1 XP_011271481.1 - 0.0067 16.1 0.7 2.6 7.8 0.0 3.3 2 1 0 2 2 2 2 Leucine rich repeat F-box-like_2 PF13013.1 XP_011271481.1 - 0.0081 15.8 0.0 0.029 14.1 0.0 1.9 2 0 0 2 2 2 1 F-box-like domain F-box PF00646.28 XP_011271481.1 - 0.3 10.7 2.9 0.3 10.7 0.5 2.2 2 0 0 2 2 2 0 F-box domain LRR_6 PF13516.1 XP_011271481.1 - 2.7 8.3 9.5 28 5.1 0.0 4.9 5 1 1 6 6 6 0 Leucine Rich repeat tRNA_anti-codon PF01336.20 XP_011271483.1 - 4.1e-10 39.3 1.3 1.1e-09 37.9 0.9 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RPA_C PF08784.6 XP_011271483.1 - 1.2e-05 25.6 0.9 2.6e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 Replication protein A C terminal Rrf2 PF02082.15 XP_011271483.1 - 0.028 14.5 0.0 0.068 13.2 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator DKNYY PF13644.1 XP_011271483.1 - 0.039 14.2 0.4 0.054 13.7 0.2 1.3 1 0 0 1 1 1 0 DKNYY family Ribosomal_S8 PF00410.14 XP_011271485.1 - 4.9e-26 91.0 0.0 6.7e-26 90.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 F-box-like PF12937.2 XP_011271486.1 - 3.4e-07 29.8 0.3 1e-06 28.3 0.2 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 XP_011271486.1 - 2.6e-05 23.7 0.1 2.6e-05 23.7 0.1 2.9 4 0 0 4 4 4 1 F-box domain Glyco_hydro_72 PF03198.9 XP_011271487.1 - 1.3e-131 438.3 3.9 1.7e-131 437.9 2.7 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 XP_011271487.1 - 0.022 13.9 0.2 0.14 11.3 0.0 2.0 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) DUF2401 PF10287.4 XP_011271488.1 - 7e-98 326.8 4.1 7e-98 326.8 2.8 2.0 2 1 1 3 3 3 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.4 XP_011271488.1 - 4.7e-31 106.7 2.1 1.9e-30 104.7 0.1 2.6 2 0 0 2 2 2 1 Glycine-rich protein domain (DUF2403) Mcm10 PF09332.6 XP_011271488.1 - 7.4 5.8 11.1 11 5.2 7.7 1.3 1 0 0 1 1 1 0 Mcm10 replication factor Gly_transf_sug PF04488.10 XP_011271489.1 - 1.8e-20 73.2 0.1 3.9e-20 72.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif DUF3087 PF11286.3 XP_011271489.1 - 0.029 13.5 0.1 0.053 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) TcdA_TcdB PF12919.2 XP_011271489.1 - 0.076 11.4 1.8 0.9 7.9 0.0 2.4 3 0 0 3 3 3 0 TcdA/TcdB catalytic glycosyltransferase domain DUF2075 PF09848.4 XP_011271490.1 - 5.7e-98 328.1 0.1 7.3e-98 327.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 XP_011271490.1 - 2.2e-09 37.5 0.0 4.4e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 XP_011271490.1 - 1.5e-05 25.0 0.0 2.7e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.18 XP_011271490.1 - 3.3e-05 23.8 0.6 9.1e-05 22.3 0.1 2.0 2 0 0 2 2 1 1 50S ribosome-binding GTPase AAA PF00004.24 XP_011271490.1 - 0.00015 21.9 0.1 0.00033 20.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 XP_011271490.1 - 0.00052 19.7 0.0 0.0011 18.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain PIF1 PF05970.9 XP_011271490.1 - 0.00055 18.9 0.5 0.0014 17.6 0.4 1.7 1 1 0 1 1 1 1 PIF1-like helicase AAA_14 PF13173.1 XP_011271490.1 - 0.00073 19.4 1.0 0.0035 17.2 0.7 2.2 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 XP_011271490.1 - 0.0019 18.0 7.1 0.14 12.0 0.1 2.9 2 1 1 3 3 2 2 Type III restriction enzyme, res subunit AAA_18 PF13238.1 XP_011271490.1 - 0.0035 17.6 0.8 0.0076 16.5 0.1 2.0 2 0 0 2 2 1 1 AAA domain AAA_30 PF13604.1 XP_011271490.1 - 0.0057 16.2 0.0 0.043 13.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 XP_011271490.1 - 0.0082 15.0 0.0 0.013 14.4 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein Arch_ATPase PF01637.13 XP_011271490.1 - 0.009 15.7 4.1 0.027 14.1 2.1 2.3 1 1 0 1 1 1 1 Archaeal ATPase SRP54 PF00448.17 XP_011271490.1 - 0.012 15.0 0.0 0.025 14.0 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain MCM PF00493.18 XP_011271490.1 - 0.022 13.6 0.0 5.2 5.7 0.0 2.2 2 0 0 2 2 2 0 MCM2/3/5 family Miro PF08477.8 XP_011271490.1 - 0.038 14.4 1.2 0.85 10.1 0.8 2.6 1 1 0 1 1 1 0 Miro-like protein RNA_helicase PF00910.17 XP_011271490.1 - 0.057 13.5 0.0 0.18 11.9 0.0 1.9 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.22 XP_011271490.1 - 0.063 13.5 0.1 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 ABC transporter DUF258 PF03193.11 XP_011271490.1 - 0.069 12.3 0.1 0.13 11.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_19 PF13245.1 XP_011271490.1 - 0.092 12.5 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain DEAD PF00270.24 XP_011271490.1 - 0.11 12.0 0.4 0.47 9.9 0.1 1.9 1 1 0 1 1 1 0 DEAD/DEAH box helicase Acyltransferase PF01553.16 XP_011271491.1 - 3.3e-18 65.4 0.1 8.6e-18 64.0 0.0 1.7 1 0 0 1 1 1 1 Acyltransferase CYSTM PF12734.2 XP_011271492.1 - 5.1e-12 45.6 11.2 5.1e-12 45.6 7.8 4.6 3 2 1 4 4 4 2 Cysteine-rich TM module stress tolerance Pro-rich PF15240.1 XP_011271492.1 - 1.4 8.9 31.7 2 8.4 21.9 1.2 1 0 0 1 1 1 0 Proline-rich PAT1 PF09770.4 XP_011271492.1 - 3.5 5.7 12.7 4.1 5.5 8.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pex14_N PF04695.8 XP_011271492.1 - 6.5 6.8 10.4 3e+02 1.4 7.2 2.2 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region IFP_35_N PF07334.8 XP_011271493.1 - 2 8.4 7.7 0.63 10.0 2.1 2.4 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DUF972 PF06156.8 XP_011271493.1 - 2.3 8.6 16.8 1.4 9.3 2.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) bZIP_1 PF00170.16 XP_011271493.1 - 9.8 6.2 11.7 7.7 6.5 1.3 2.7 2 0 0 2 2 2 0 bZIP transcription factor Smg4_UPF3 PF03467.10 XP_011271494.1 - 8.6e-18 64.9 11.4 8.6e-18 64.9 7.9 2.4 1 1 1 2 2 2 1 Smg-4/UPF3 family PCI PF01399.22 XP_011271495.1 - 1.1e-05 25.6 0.8 6.3e-05 23.2 0.1 2.5 2 0 0 2 2 2 1 PCI domain Metallophos PF00149.23 XP_011271496.1 - 3.7e-42 144.0 0.2 4.6e-42 143.7 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Arginosuc_synth PF00764.14 XP_011271497.1 - 2.7e-156 520.4 0.0 3.2e-156 520.2 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.8 XP_011271497.1 - 4.6e-05 22.7 0.0 7.2e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.16 XP_011271497.1 - 6.8e-05 22.4 0.0 9.7e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase tRNA_Me_trans PF03054.11 XP_011271497.1 - 0.0029 16.2 0.0 0.0051 15.4 0.0 1.4 1 0 0 1 1 1 1 tRNA methyl transferase Glyco_transf_15 PF01793.11 XP_011271498.1 - 3.6e-124 414.0 22.5 4.3e-124 413.7 15.6 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Glyco_transf_15 PF01793.11 XP_011271499.1 - 1.2e-135 451.7 17.1 1.5e-135 451.4 11.8 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase AA_permease PF00324.16 XP_011271501.1 - 4.2e-113 378.2 43.1 5.2e-113 377.9 29.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 XP_011271501.1 - 3.4e-34 118.1 43.2 5.5e-34 117.4 30.0 1.3 1 0 0 1 1 1 1 Amino acid permease FA_hydroxylase PF04116.8 XP_011271502.1 - 7.6e-13 48.8 25.3 7.6e-13 48.8 17.5 2.1 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily Bac_luciferase PF00296.15 XP_011271503.1 - 6.4e-53 179.8 0.0 9e-53 179.3 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase DUF1827 PF08860.5 XP_011271503.1 - 0.0038 17.2 0.1 1.3 9.1 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF1827) Bac_luciferase PF00296.15 XP_011271504.1 - 6.1e-52 176.6 0.0 8.2e-52 176.2 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase DUF1827 PF08860.5 XP_011271504.1 - 0.045 13.8 0.0 4.7 7.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1827) adh_short PF00106.20 XP_011271505.1 - 6.5e-20 71.7 0.0 8.2e-20 71.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 XP_011271505.1 - 5.9e-10 39.3 0.1 7.2e-10 39.0 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 XP_011271505.1 - 1.9e-05 24.2 0.1 2.9e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 XP_011271505.1 - 0.00019 21.1 0.0 0.00043 20.0 0.0 1.5 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.5 XP_011271505.1 - 0.00094 18.3 2.4 0.034 13.3 1.6 2.1 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) RmlD_sub_bind PF04321.12 XP_011271505.1 - 0.001 18.0 0.0 0.0016 17.3 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain DUF1128 PF06569.6 XP_011271505.1 - 0.84 9.4 5.1 0.83 9.4 0.0 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF1128) HSP70 PF00012.15 XP_011271506.1 - 5e-267 886.7 7.4 5.6e-267 886.5 5.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 XP_011271506.1 - 1.9e-17 62.8 0.1 3.5e-16 58.7 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 XP_011271506.1 - 0.00047 19.8 0.0 0.00096 18.8 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 XP_011271506.1 - 0.0035 16.5 1.5 0.036 13.1 0.1 2.6 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase DDR PF08841.5 XP_011271506.1 - 0.033 13.0 0.5 0.68 8.7 0.1 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain ATP_bind_3 PF01171.15 XP_011271507.1 - 1.9e-45 154.5 0.2 3.5e-45 153.7 0.1 1.4 1 0 0 1 1 1 1 PP-loop family PAPS_reduct PF01507.14 XP_011271507.1 - 5.6e-07 29.5 0.0 4.3e-06 26.6 0.0 2.2 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Asn_synthase PF00733.16 XP_011271507.1 - 0.0007 19.1 0.0 0.0012 18.3 0.0 1.4 1 0 0 1 1 1 1 Asparagine synthase eIF3_N PF09440.5 XP_011271507.1 - 0.013 15.6 3.9 0.028 14.5 2.7 1.5 1 0 0 1 1 1 0 eIF3 subunit 6 N terminal domain tRNA_Me_trans PF03054.11 XP_011271507.1 - 0.057 11.9 3.4 0.54 8.7 0.0 3.2 3 1 1 4 4 4 0 tRNA methyl transferase DUF2392 PF10288.4 XP_011271507.1 - 0.28 11.5 5.1 0.15 12.3 1.6 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2392) AAR2 PF05282.6 XP_011271508.1 - 3.5e-62 210.4 16.9 4.4e-62 210.1 11.7 1.0 1 0 0 1 1 1 1 AAR2 protein tRNA-synt_1 PF00133.17 XP_011271509.1 - 6.9e-235 780.6 1.7 8.5e-235 780.3 0.2 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 XP_011271509.1 - 3.1e-25 88.7 0.0 6.9e-25 87.5 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 XP_011271509.1 - 3.7e-19 68.6 2.7 8.8e-08 31.2 0.1 4.2 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 XP_011271509.1 - 0.0012 18.0 0.1 0.021 13.9 0.0 2.8 4 0 0 4 4 4 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1_2 PF13603.1 XP_011271509.1 - 0.077 12.2 0.1 0.19 10.9 0.0 1.6 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 Atg8 PF02991.11 XP_011271510.1 - 2.3e-46 156.0 0.1 2.7e-46 155.8 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 XP_011271510.1 - 2.4e-06 27.6 0.0 3.2e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 DUF1751 PF08551.5 XP_011271511.1 - 7.6e-27 93.5 7.2 1.8e-26 92.3 5.0 1.7 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 XP_011271511.1 - 0.012 15.6 8.9 0.012 15.6 6.2 2.4 2 1 0 2 2 2 0 Rhomboid family HLH PF00010.21 XP_011271512.1 - 8.5e-08 31.7 2.2 1.8e-07 30.7 1.5 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF706 PF05153.10 XP_011271512.1 - 0.11 11.8 0.5 0.14 11.4 0.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF706) Herpes_DNAp_acc PF04929.7 XP_011271512.1 - 0.23 10.4 8.0 0.28 10.0 5.6 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor EF-hand_4 PF12763.2 XP_011271513.1 - 3e-21 75.1 0.0 2.4e-09 36.8 0.0 2.5 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand DUF1720 PF08226.6 XP_011271513.1 - 2e-13 50.2 101.5 2.7e-07 30.5 17.1 10.2 7 3 3 10 10 10 4 Domain of unknown function (DUF1720) EF-hand_7 PF13499.1 XP_011271513.1 - 5e-05 23.3 0.1 0.37 10.9 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 XP_011271513.1 - 0.0017 17.5 0.0 1.9 7.9 0.0 2.8 2 0 0 2 2 2 2 EF hand DUF4201 PF13870.1 XP_011271513.1 - 0.0063 15.9 5.8 0.0063 15.9 4.0 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4201) MutS_V PF00488.16 XP_011271514.1 - 6.2e-66 222.1 2.0 1.5e-65 220.9 0.8 2.0 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.13 XP_011271514.1 - 1.3e-30 106.7 4.9 5.2e-30 104.7 2.6 2.4 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.12 XP_011271514.1 - 8.7e-11 42.0 2.1 3e-10 40.3 0.0 2.7 3 0 0 3 3 3 1 MutS domain II MutS_IV PF05190.13 XP_011271514.1 - 8.6e-10 38.6 1.2 8.6e-10 38.6 0.8 2.0 2 0 0 2 2 2 1 MutS family domain IV ABC_membrane_2 PF06472.10 XP_011271515.1 - 5.8e-90 301.2 8.6 1.1e-89 300.3 6.0 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 XP_011271515.1 - 2.5e-19 69.9 0.0 6.8e-19 68.5 0.0 1.8 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 XP_011271515.1 - 0.001 18.3 0.2 0.03 13.5 0.1 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 XP_011271515.1 - 2 8.6 17.4 0.023 15.0 3.7 3.2 3 1 0 3 3 3 0 AAA domain DUF218 PF02698.12 XP_011271516.1 - 0.00023 20.6 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 DUF218 domain Nop53 PF07767.6 XP_011271517.1 - 1.2e-88 297.7 49.9 1.4e-88 297.5 34.6 1.0 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) CENP-B_dimeris PF09026.5 XP_011271517.1 - 0.16 12.2 12.3 0.38 11.0 8.5 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain EBV-NA3 PF05009.7 XP_011271517.1 - 0.96 8.6 5.8 1.7 7.7 4.0 1.4 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) CDC45 PF02724.9 XP_011271517.1 - 6.3 4.6 23.0 10 4.0 16.0 1.3 1 0 0 1 1 1 0 CDC45-like protein chaperone_DMP PF10448.4 XP_011271518.1 - 7e-09 35.7 0.1 8.4e-09 35.4 0.1 1.2 1 0 0 1 1 1 1 20S proteasome chaperone BPL_N PF09825.4 XP_011271519.1 - 3.3 6.4 12.2 0.12 11.1 4.0 1.7 2 1 0 2 2 2 0 Biotin-protein ligase, N terminal DHFR_1 PF00186.14 XP_011271520.1 - 5.9e-33 113.7 0.2 1.9e-32 112.0 0.1 1.7 1 1 0 1 1 1 1 Dihydrofolate reductase Fer4_12 PF13353.1 XP_011271520.1 - 0.055 13.5 1.1 0.076 13.1 0.7 1.4 1 1 0 1 1 1 0 4Fe-4S single cluster domain SHD1 PF03983.7 XP_011271520.1 - 0.056 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 SLA1 homology domain 1, SHD1 RibD_C PF01872.12 XP_011271520.1 - 0.12 11.9 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 RibD C-terminal domain DSPc PF00782.15 XP_011271521.1 - 8.4e-18 64.2 1.4 4.3e-12 45.7 0.0 3.8 2 2 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 XP_011271521.1 - 0.0037 16.6 0.2 0.086 12.1 0.0 2.6 3 0 0 3 3 3 1 Protein-tyrosine phosphatase AICARFT_IMPCHas PF01808.13 XP_011271521.1 - 0.17 10.9 0.6 0.3 10.1 0.4 1.3 1 0 0 1 1 1 0 AICARFT/IMPCHase bienzyme Fungal_trans_2 PF11951.3 XP_011271522.1 - 1.9e-42 145.2 0.0 3.5e-42 144.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 XP_011271522.1 - 8.6e-10 38.3 8.3 1.6e-09 37.5 5.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 XP_011271523.1 - 1e-52 178.9 2.5 4.7e-52 176.7 0.1 2.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011271523.1 - 3.3e-28 98.4 0.0 6.2e-28 97.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 XP_011271523.1 - 0.011 15.4 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 XP_011271523.1 - 0.033 13.5 0.3 9.4 5.5 0.0 2.6 1 1 0 2 2 2 0 PhoP regulatory network protein YrbL Kdo PF06293.9 XP_011271523.1 - 0.043 12.8 0.0 0.089 11.8 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Lipoprotein_7 PF01540.11 XP_011271524.1 - 0.066 12.2 0.2 0.067 12.2 0.1 1.1 1 0 0 1 1 1 0 Adhesin lipoprotein MFS_1 PF07690.11 XP_011271525.1 - 7.2e-31 107.1 38.8 7.2e-31 107.1 26.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 XP_011271525.1 - 2.7e-08 32.4 6.7 6.2e-08 31.2 4.6 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ABC_membrane_2 PF06472.10 XP_011271526.1 - 1.2e-67 228.0 1.1 2.3e-67 227.0 0.7 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 XP_011271526.1 - 7.1e-15 55.5 0.0 5.2e-14 52.7 0.0 2.4 1 1 0 1 1 1 1 ABC transporter IstB_IS21 PF01695.12 XP_011271526.1 - 0.01 15.2 0.2 0.031 13.7 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_29 PF13555.1 XP_011271526.1 - 0.038 13.5 0.0 0.087 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 XP_011271526.1 - 0.048 13.9 0.3 0.048 13.9 0.2 3.6 3 1 1 4 4 4 0 AAA domain NACHT PF05729.7 XP_011271526.1 - 0.064 12.9 0.0 0.17 11.5 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Mg_chelatase PF01078.16 XP_011271526.1 - 0.16 11.1 0.0 0.32 10.1 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Methyltransf_PK PF05891.7 XP_011271527.1 - 2.4e-88 295.0 0.1 2.7e-88 294.9 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.1 XP_011271527.1 - 5.1e-06 26.3 0.0 7.7e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 XP_011271527.1 - 0.00025 21.6 0.0 0.00049 20.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain P-mevalo_kinase PF04275.9 XP_011271527.1 - 0.004 16.8 0.0 0.0078 15.9 0.0 1.4 1 0 0 1 1 1 1 Phosphomevalonate kinase Methyltransf_2 PF00891.13 XP_011271527.1 - 0.021 13.9 0.1 0.042 13.0 0.1 1.6 1 1 0 1 1 1 0 O-methyltransferase Methyltransf_11 PF08241.7 XP_011271527.1 - 0.063 13.7 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain SecY PF00344.15 XP_011271528.1 - 8.9e-61 205.7 28.7 1.2e-60 205.3 19.9 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 XP_011271528.1 - 8.6e-08 31.5 0.1 4.3e-07 29.3 0.0 2.4 2 0 0 2 2 2 1 Plug domain of Sec61p TRIQK PF15168.1 XP_011271528.1 - 1.5 8.8 3.3 0.55 10.1 0.1 2.0 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family Spc7 PF08317.6 XP_011271529.1 - 4.3e-37 127.4 29.7 4.3e-37 127.4 20.6 3.6 4 1 1 5 5 5 1 Spc7 kinetochore protein Spc7_N PF15402.1 XP_011271529.1 - 0.81 7.6 41.6 0.022 12.7 0.9 4.2 1 1 2 4 4 4 0 N-terminus of kinetochore NMS complex subunit Spc7 WD40 PF00400.27 XP_011271530.1 - 7.8e-22 76.2 15.7 1.2e-09 37.6 0.0 9.3 9 0 0 9 9 9 7 WD domain, G-beta repeat UCH_1 PF13423.1 XP_011271531.1 - 1.2e-35 123.4 0.0 1.8e-35 122.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 XP_011271531.1 - 1.2e-20 74.4 0.0 2.2e-20 73.5 0.0 1.5 1 0 0 1 1 1 1 Exonuclease UCH PF00443.24 XP_011271531.1 - 3.3e-06 26.4 0.1 1.2e-05 24.6 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase BBS2_Mid PF14783.1 XP_011271531.1 - 0.016 14.9 0.0 0.07 12.9 0.0 2.1 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region TCO89 PF10452.4 XP_011271532.1 - 1.4e-28 100.1 25.5 1.4e-28 100.1 17.6 3.4 1 1 2 3 3 3 2 TORC1 subunit TCO89 Sec1 PF00995.18 XP_011271533.1 - 5.8e-142 474.2 15.5 6.6e-142 474.0 10.7 1.0 1 0 0 1 1 1 1 Sec1 family YebO PF13974.1 XP_011271533.1 - 0.035 13.8 1.2 0.18 11.5 0.1 2.5 2 0 0 2 2 2 0 YebO-like protein IncA PF04156.9 XP_011271533.1 - 0.58 9.7 5.6 5.8 6.4 2.9 2.6 1 1 1 2 2 2 0 IncA protein PK PF00224.16 XP_011271534.1 - 3.1e-167 555.5 1.7 4e-167 555.1 1.2 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 XP_011271534.1 - 1.2e-29 102.2 0.0 2.9e-29 100.9 0.0 1.7 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 XP_011271534.1 - 0.0022 16.9 0.4 0.0059 15.5 0.1 1.8 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family PHD PF00628.24 XP_011271535.1 - 1.6e-09 37.2 8.3 3.5e-09 36.2 5.8 1.6 1 0 0 1 1 1 1 PHD-finger IMS PF00817.15 XP_011271536.1 - 5.1e-39 133.4 0.0 1.2e-38 132.2 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 XP_011271536.1 - 1.4e-13 50.9 0.0 4.6e-13 49.1 0.0 1.9 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain BRCT PF00533.21 XP_011271536.1 - 1.1e-06 28.6 0.2 1.7e-05 24.8 0.1 3.0 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 XP_011271536.1 - 0.00085 19.1 0.1 0.0019 18.0 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain DUF4414 PF14377.1 XP_011271536.1 - 0.0042 16.9 12.3 0.015 15.1 0.8 4.3 5 1 0 5 5 5 2 Domain of unknown function (DUF4414) IMS_HHH PF11798.3 XP_011271536.1 - 0.011 15.7 0.0 0.11 12.5 0.0 2.6 3 0 0 3 3 3 0 IMS family HHH motif AMP-binding PF00501.23 XP_011271537.1 - 6.8e-91 304.7 0.0 8.2e-91 304.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 XP_011271537.1 - 6.9e-19 68.5 0.1 1.9e-17 63.9 0.1 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain TRP PF06011.7 XP_011271538.1 - 3.1e-160 533.5 29.5 3.9e-160 533.1 20.4 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 XP_011271538.1 - 2.3e-46 157.3 1.7 5.1e-46 156.2 1.2 1.6 1 0 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.10 XP_011271538.1 - 0.00032 20.9 0.1 0.00062 20.0 0.1 1.4 1 0 0 1 1 1 1 ML domain Tmemb_9 PF05434.6 XP_011271538.1 - 1.1 8.9 8.1 14 5.3 0.0 3.5 3 0 0 3 3 3 0 TMEM9 DLH PF01738.13 XP_011271539.1 - 1.9e-27 95.9 0.0 2.3e-27 95.7 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 XP_011271539.1 - 7.6e-08 32.2 0.0 9.7e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ubie_methyltran PF01209.13 XP_011271541.1 - 2.5e-88 295.1 0.1 2.8e-88 294.9 0.1 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 XP_011271541.1 - 5.1e-12 45.6 0.0 8.6e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 XP_011271541.1 - 2.4e-10 40.7 0.1 9e-10 38.9 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 XP_011271541.1 - 3.2e-10 40.3 0.0 5.9e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 XP_011271541.1 - 3e-08 33.5 0.0 4.3e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 XP_011271541.1 - 1.2e-06 29.1 0.0 2.4e-06 28.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 XP_011271541.1 - 2.2e-06 27.9 0.0 4.4e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 XP_011271541.1 - 0.011 15.3 0.0 0.029 14.0 0.0 1.7 2 0 0 2 2 2 0 Hypothetical methyltransferase Methyltransf_5 PF01795.14 XP_011271541.1 - 0.022 14.0 0.0 0.31 10.2 0.0 2.1 1 1 1 2 2 2 0 MraW methylase family Methyltransf_26 PF13659.1 XP_011271541.1 - 0.076 13.0 0.0 0.31 11.0 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Med1 PF10744.4 XP_011271542.1 - 2.3e-21 76.0 7.6 2.3e-21 76.0 5.2 1.6 2 0 0 2 2 2 1 Mediator of RNA polymerase II transcription subunit 1 TPR_1 PF00515.23 XP_011271543.1 - 8e-55 180.3 23.6 1.6e-07 30.6 0.0 11.7 10 2 0 10 10 10 9 Tetratricopeptide repeat TPR_11 PF13414.1 XP_011271543.1 - 9.3e-55 182.1 35.6 1.7e-12 46.7 0.0 6.8 2 2 5 8 8 8 8 TPR repeat TPR_2 PF07719.12 XP_011271543.1 - 9.1e-49 159.4 24.4 3.2e-06 26.6 0.0 11.2 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_8 PF13181.1 XP_011271543.1 - 1.3e-34 115.3 11.9 0.002 17.7 0.0 10.5 8 1 2 10 10 10 9 Tetratricopeptide repeat TPR_12 PF13424.1 XP_011271543.1 - 7.1e-34 115.5 23.2 1.1e-07 31.6 0.2 7.7 3 2 4 7 7 7 7 Tetratricopeptide repeat TPR_17 PF13431.1 XP_011271543.1 - 1.3e-29 99.8 34.5 0.0012 18.8 0.0 12.0 12 1 0 12 12 11 7 Tetratricopeptide repeat TPR_16 PF13432.1 XP_011271543.1 - 1.3e-28 99.0 46.8 1.7e-06 28.5 0.0 7.5 7 1 0 7 7 6 6 Tetratricopeptide repeat TPR_14 PF13428.1 XP_011271543.1 - 4.4e-25 85.8 40.4 0.00026 21.3 1.0 11.5 3 3 8 11 11 10 8 Tetratricopeptide repeat TPR_7 PF13176.1 XP_011271543.1 - 7.5e-24 81.6 14.7 0.00031 20.3 0.1 10.3 10 1 0 10 10 10 6 Tetratricopeptide repeat TPR_6 PF13174.1 XP_011271543.1 - 8.8e-13 47.7 41.8 0.0061 16.9 0.0 11.3 10 1 0 10 10 9 4 Tetratricopeptide repeat TPR_19 PF14559.1 XP_011271543.1 - 2.6e-12 46.8 14.3 4.6e-05 23.6 1.1 9.2 6 3 2 8 8 6 6 Tetratricopeptide repeat TPR_9 PF13371.1 XP_011271543.1 - 3.4e-08 33.2 39.0 0.0036 17.1 0.0 7.3 5 2 2 7 7 6 5 Tetratricopeptide repeat TPR_15 PF13429.1 XP_011271543.1 - 0.0008 18.5 0.1 0.0008 18.5 0.1 6.1 3 2 1 5 5 4 2 Tetratricopeptide repeat ChAPs PF09295.5 XP_011271543.1 - 0.1 11.3 0.1 0.1 11.3 0.0 3.9 4 0 0 4 4 3 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.1 XP_011271543.1 - 0.99 9.4 27.4 0.4 10.6 0.6 7.7 9 1 0 9 9 9 0 Tetratricopeptide repeat PPTA PF01239.17 XP_011271543.1 - 1.3 8.5 3.5 4 6.9 0.0 3.4 5 0 0 5 5 5 0 Protein prenyltransferase alpha subunit repeat NARP1 PF12569.3 XP_011271543.1 - 5.5 5.6 0.0 5.5 5.6 0.0 7.4 5 4 3 9 9 5 0 NMDA receptor-regulated protein 1 NUDIX PF00293.23 XP_011271544.1 - 2.9e-17 62.5 0.0 9.1e-17 60.9 0.0 1.7 2 0 0 2 2 2 1 NUDIX domain eIF3g PF12353.3 XP_011271545.1 - 0.0001 22.1 2.4 0.0001 22.1 1.7 2.9 3 0 0 3 3 3 1 Eukaryotic translation initiation factor 3 subunit G Herpes_UL69 PF05459.7 XP_011271545.1 - 0.042 12.9 0.4 1.6 7.8 0.0 2.5 2 0 0 2 2 2 0 Herpesvirus transcriptional regulator family Radical_SAM PF04055.16 XP_011271545.1 - 0.051 13.7 1.8 5.2 7.2 0.0 2.9 2 1 1 3 3 3 0 Radical SAM superfamily zf-CCHC_6 PF15288.1 XP_011271545.1 - 0.73 9.5 8.5 1.2 8.9 4.8 2.2 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.1 XP_011271545.1 - 2.5 7.8 12.0 0.71 9.5 0.5 2.9 2 1 1 3 3 3 0 Zinc knuckle zf-CCHC_3 PF13917.1 XP_011271545.1 - 5.1 6.9 8.0 1.2 8.9 0.8 2.5 1 1 1 2 2 2 0 Zinc knuckle Motile_Sperm PF00635.21 XP_011271546.1 - 7.4e-08 32.0 0.0 2.7e-07 30.1 0.0 2.0 1 1 1 2 2 2 1 MSP (Major sperm protein) domain DUF912 PF06024.7 XP_011271546.1 - 1.6 8.8 8.5 0.35 10.9 1.1 2.3 1 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Ribosomal_L32e PF01655.13 XP_011271547.1 - 1.7e-47 159.9 0.6 2e-47 159.7 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 DUF4301 PF14134.1 XP_011271547.1 - 0.062 11.8 0.0 0.066 11.7 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4301) Rox3 PF08633.5 XP_011271548.1 - 4.2e-24 85.9 2.7 1.8e-22 80.6 0.1 2.0 1 1 0 2 2 2 2 Rox3 mediator complex subunit PG_binding_4 PF12229.3 XP_011271548.1 - 0.066 13.4 0.0 0.15 12.3 0.0 1.5 1 1 0 1 1 1 0 Putative peptidoglycan binding domain Fmp27_WPPW PF10359.4 XP_011271549.1 - 1.3e-108 363.4 12.2 1.3e-108 363.4 8.5 2.5 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Apt1 PF10351.4 XP_011271549.1 - 6.3e-106 354.9 14.7 6.3e-106 354.9 10.2 2.2 3 0 0 3 3 3 1 Golgi-body localisation protein domain Fmp27 PF10344.4 XP_011271549.1 - 2.1e-57 194.5 34.5 4.9e-57 193.2 23.9 1.6 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 Fmp27_GFWDK PF10347.4 XP_011271549.1 - 7.9e-52 175.3 0.1 3.6e-51 173.1 0.0 2.2 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 XP_011271549.1 - 1.3e-48 164.7 1.1 1.3e-48 164.7 0.8 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 XP_011271549.1 - 3.9e-30 104.3 3.8 1.1e-29 102.8 0.0 3.9 4 0 0 4 4 4 1 RNA pol II promoter Fmp27 protein domain RRM_6 PF14259.1 XP_011271550.1 - 3.7e-08 33.2 0.0 5.6e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 XP_011271550.1 - 6.5e-06 25.6 0.0 1.3e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 XP_011271550.1 - 0.0083 15.9 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Daxx PF03344.10 XP_011271550.1 - 3.2 6.1 16.9 4.9 5.5 11.7 1.2 1 0 0 1 1 1 0 Daxx Family zf-RING_2 PF13639.1 XP_011271551.1 - 3.9e-13 48.9 7.3 6.5e-13 48.2 5.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-Apc11 PF12861.2 XP_011271551.1 - 1.3e-06 28.1 2.2 5.5e-06 26.1 2.0 1.6 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 XP_011271551.1 - 1.9e-06 27.4 6.9 3.3e-06 26.6 4.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 XP_011271551.1 - 2.1e-06 27.7 7.1 7.1e-06 26.0 4.9 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 XP_011271551.1 - 3.3e-06 26.7 5.8 5.4e-06 26.0 4.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 XP_011271551.1 - 3.3e-05 23.8 8.6 5.5e-05 23.1 5.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 XP_011271551.1 - 0.00052 19.6 4.1 0.00082 18.9 2.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 XP_011271551.1 - 0.022 14.4 6.2 0.04 13.6 4.3 1.5 1 0 0 1 1 1 0 PHD-finger RINGv PF12906.2 XP_011271551.1 - 0.035 14.1 6.9 0.065 13.2 4.8 1.5 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.1 XP_011271551.1 - 0.072 12.9 5.1 0.16 11.8 3.5 1.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 XP_011271551.1 - 0.076 12.7 6.0 0.23 11.2 4.2 1.9 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_1 PF14446.1 XP_011271551.1 - 0.085 12.6 6.2 0.4 10.4 4.3 2.0 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 zf-RING_4 PF14570.1 XP_011271551.1 - 0.42 10.2 7.5 0.82 9.3 5.2 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 XP_011271551.1 - 0.61 10.0 4.4 2 8.4 3.0 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain SPX PF03105.14 XP_011271551.1 - 1.3 8.7 19.5 2.3 7.8 3.2 2.3 2 0 0 2 2 2 0 SPX domain Peptidase_C97 PF05903.9 XP_011271552.1 - 9e-29 100.2 0.1 1e-28 100.0 0.1 1.0 1 0 0 1 1 1 1 PPPDE putative peptidase domain UPF0167 PF03691.9 XP_011271552.1 - 0.016 14.6 0.0 0.019 14.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0167) Exo70 PF03081.10 XP_011271552.1 - 0.062 12.0 0.0 0.08 11.7 0.0 1.1 1 0 0 1 1 1 0 Exo70 exocyst complex subunit PWWP PF00855.12 XP_011271553.1 - 7.4e-14 51.7 0.8 4.2e-13 49.3 0.6 2.4 1 0 0 1 1 1 1 PWWP domain Lipase_3 PF01764.20 XP_011271555.1 - 7.4e-25 87.2 0.0 1.6e-24 86.1 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 XP_011271555.1 - 0.024 14.0 0.5 1.3 8.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) DUF3843 PF12954.2 XP_011271555.1 - 0.044 12.8 0.0 0.056 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3843) eIF-5a PF01287.15 XP_011271556.1 - 4.3e-29 100.2 0.2 6.2e-29 99.7 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 XP_011271556.1 - 0.0016 18.0 0.4 0.0031 17.1 0.3 1.5 1 0 0 1 1 1 1 KOW motif TcdB_toxin_midN PF12256.3 XP_011271556.1 - 0.054 12.9 0.0 0.078 12.4 0.0 1.2 1 0 0 1 1 1 0 Insecticide toxin TcdB middle/N-terminal region EFP_N PF08207.7 XP_011271556.1 - 0.059 13.2 0.0 0.088 12.6 0.0 1.3 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain Erg28 PF03694.8 XP_011271557.1 - 0.0078 16.2 2.0 0.012 15.6 0.8 1.8 1 1 1 2 2 2 1 Erg28 like protein Daxx PF03344.10 XP_011271557.1 - 0.008 14.7 13.9 0.0096 14.4 9.6 1.1 1 0 0 1 1 1 1 Daxx Family BUD22 PF09073.5 XP_011271557.1 - 0.013 14.6 16.2 0.016 14.3 11.2 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.7 XP_011271557.1 - 0.089 10.7 17.6 0.1 10.4 12.2 1.2 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.7 XP_011271557.1 - 0.094 11.9 12.8 0.13 11.4 8.9 1.1 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.4 XP_011271557.1 - 0.23 10.1 21.4 0.31 9.7 14.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CobT PF06213.7 XP_011271557.1 - 0.89 8.6 17.0 1.3 8.0 11.8 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Astro_capsid PF03115.9 XP_011271557.1 - 0.97 7.6 6.5 1.2 7.2 4.5 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Merozoite_SPAM PF07133.6 XP_011271557.1 - 1 9.1 25.0 2 8.2 17.4 1.4 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) TRAP_alpha PF03896.11 XP_011271557.1 - 1.1 8.2 10.0 1.9 7.4 6.9 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Sigma70_ner PF04546.8 XP_011271557.1 - 1.6 8.2 14.5 3.2 7.3 10.0 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF1510 PF07423.6 XP_011271557.1 - 3.3 7.0 14.6 1.2 8.4 8.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) FAM176 PF14851.1 XP_011271557.1 - 4.5 6.9 8.6 13 5.4 6.0 1.8 1 0 0 1 1 1 0 FAM176 family CDC45 PF02724.9 XP_011271557.1 - 8.6 4.2 13.4 12 3.7 9.3 1.2 1 0 0 1 1 1 0 CDC45-like protein MFS_1 PF07690.11 XP_011271558.1 - 7.1e-35 120.3 8.8 3.1e-31 108.3 0.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 XP_011271558.1 - 3.9e-12 45.4 3.7 3.9e-12 45.4 2.6 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 XP_011271558.1 - 7.5e-06 24.6 5.1 2.6e-05 22.8 1.5 2.4 2 0 0 2 2 2 1 MFS/sugar transport protein TRI12 PF06609.8 XP_011271558.1 - 0.0096 14.1 0.5 0.015 13.4 0.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) UPF0052 PF01933.13 XP_011271559.1 - 2.7e-58 197.6 0.0 3.6e-58 197.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 EF-hand_7 PF13499.1 XP_011271560.1 - 1.8e-07 31.1 2.2 1.8e-07 31.1 1.5 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.1 XP_011271560.1 - 5.1e-06 25.9 1.3 0.024 14.2 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 XP_011271560.1 - 3.2e-05 23.4 1.9 0.059 13.2 0.2 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 XP_011271560.1 - 0.0014 17.7 2.0 0.016 14.4 0.1 2.5 2 0 0 2 2 2 1 EF hand Ish1 PF10281.4 XP_011271560.1 - 0.4 10.7 3.7 1.5 8.9 0.0 3.5 4 0 0 4 4 4 0 Putative stress-responsive nuclear envelope protein Ribosomal_S8e PF01201.17 XP_011271561.1 - 2e-48 163.9 3.0 2.3e-48 163.6 2.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e zf-CSL PF05207.8 XP_011271562.1 - 5e-25 86.7 1.2 7.4e-25 86.2 0.9 1.3 1 0 0 1 1 1 1 CSL zinc finger ATPase-cat_bd PF12156.3 XP_011271562.1 - 0.016 15.6 0.0 0.025 15.0 0.0 1.3 1 0 0 1 1 1 0 Putative metal-binding domain of cation transport ATPase Zn-ribbon_8 PF09723.5 XP_011271562.1 - 0.024 14.5 0.3 0.045 13.7 0.2 1.5 1 0 0 1 1 1 0 Zinc ribbon domain zf-RING_4 PF14570.1 XP_011271562.1 - 0.061 12.9 0.4 0.12 12.0 0.3 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain TF_Zn_Ribbon PF08271.7 XP_011271562.1 - 1.9 7.8 5.3 0.7 9.2 1.8 1.8 2 1 0 2 2 2 0 TFIIB zinc-binding ADH_zinc_N_2 PF13602.1 XP_011271563.1 - 5.1e-12 46.8 0.0 9e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 XP_011271563.1 - 1.4e-08 34.4 0.0 2.4e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 XP_011271563.1 - 1.4e-07 31.1 0.0 3.1e-07 30.0 0.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase UQ_con PF00179.21 XP_011271564.1 - 1.4e-28 99.1 0.0 2.7e-28 98.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme PIR PF00399.14 XP_011271565.1 - 7.9e-39 129.7 89.9 3.1e-07 29.5 3.0 6.8 6 0 0 6 6 6 6 Yeast PIR protein repeat TPP_enzyme_C PF02775.16 XP_011271565.1 - 9.3e-05 22.0 8.1 2.4 7.7 0.0 5.4 1 1 5 6 6 6 2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain SBP_bac_7 PF03480.8 XP_011271565.1 - 0.1 11.6 2.4 0.78 8.7 0.2 2.5 1 1 1 2 2 2 0 Bacterial extracellular solute-binding protein, family 7 TFIIA PF03153.8 XP_011271565.1 - 2.4 7.9 12.9 3.1 7.5 9.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.4 XP_011271565.1 - 9.8 4.3 7.9 12 4.0 5.5 1.1 1 0 0 1 1 1 0 Transmembrane protein Pribosyltran_N PF13793.1 XP_011271566.1 - 1.3e-46 157.1 1.0 5e-45 151.9 0.0 2.6 2 1 1 3 3 3 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 XP_011271566.1 - 2.9e-36 124.9 5.0 7.6e-31 107.2 1.0 2.5 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 XP_011271566.1 - 7.1e-12 45.1 0.6 8.8e-11 41.6 0.4 2.4 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 XP_011271566.1 - 0.022 13.9 0.1 0.038 13.1 0.1 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase SPA PF08616.5 XP_011271566.1 - 0.051 13.2 0.0 0.25 11.0 0.0 2.0 2 0 0 2 2 2 0 Stabilization of polarity axis Aldo_ket_red PF00248.16 XP_011271567.1 - 1.9e-46 158.1 0.2 2.2e-46 157.9 0.2 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Peptidase_C8 PF03569.8 XP_011271567.1 - 0.1 11.8 0.0 13 4.9 0.0 2.2 2 0 0 2 2 2 0 Peptidase family C8 AOX PF01786.12 XP_011271568.1 - 3.4e-86 287.9 0.0 4e-86 287.6 0.0 1.0 1 0 0 1 1 1 1 Alternative oxidase PhzC-PhzF PF02567.11 XP_011271569.1 - 1.8e-55 188.1 0.0 2.2e-55 187.8 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Pro_racemase PF05544.6 XP_011271569.1 - 4.7e-07 28.9 0.0 7.8e-07 28.2 0.0 1.3 1 0 0 1 1 1 1 Proline racemase UCH PF00443.24 XP_011271570.1 - 8.8e-70 234.8 7.1 1.9e-69 233.7 4.9 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 XP_011271570.1 - 1.4e-31 110.1 2.6 1e-28 100.6 0.3 3.4 5 0 0 5 5 5 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 XP_011271570.1 - 0.097 11.9 2.7 0.34 10.1 0.6 2.4 1 1 1 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase zf-RVT PF13966.1 XP_011271571.1 - 9.4e-06 25.8 1.1 2.6e-05 24.4 0.8 1.9 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Fungal_trans PF04082.13 XP_011271572.1 - 7.4e-65 218.3 4.1 1.4e-64 217.5 2.8 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 XP_011271572.1 - 1.3e-08 34.6 9.2 0.0011 19.1 1.3 3.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 XP_011271572.1 - 2.6e-06 27.3 8.2 0.0014 18.7 0.5 3.3 2 0 0 2 2 2 2 C2H2-type zinc finger DUF3920 PF13058.1 XP_011271572.1 - 0.038 13.8 0.8 0.29 10.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3920) ABC_tran PF00005.22 XP_011271573.1 - 9.8e-50 168.4 0.9 2.4e-24 86.1 0.0 2.9 3 0 0 3 3 2 2 ABC transporter ABC2_membrane PF01061.19 XP_011271573.1 - 4.4e-31 107.6 41.6 1.4e-20 73.3 13.1 2.7 3 0 0 3 3 2 2 ABC-2 type transporter AAA_21 PF13304.1 XP_011271573.1 - 1.7e-17 64.3 15.1 3.2e-07 30.6 2.4 4.9 2 2 0 2 2 2 2 AAA domain SMC_N PF02463.14 XP_011271573.1 - 6.4e-14 51.7 0.1 1.1e-06 28.0 0.0 2.7 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 XP_011271573.1 - 7.3e-11 41.7 2.3 0.014 14.4 0.5 4.5 3 1 1 4 4 4 2 AAA ATPase domain AAA_23 PF13476.1 XP_011271573.1 - 1.4e-09 38.6 4.3 7.3e-06 26.4 0.1 3.1 2 1 1 3 3 2 2 AAA domain DUF258 PF03193.11 XP_011271573.1 - 6.4e-09 35.2 0.4 0.0029 16.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 XP_011271573.1 - 3.7e-08 33.0 0.1 0.0071 15.7 0.0 4.5 5 0 0 5 5 5 1 AAA domain AAA_29 PF13555.1 XP_011271573.1 - 4.1e-07 29.4 1.9 0.023 14.2 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 XP_011271573.1 - 7.8e-07 29.9 0.0 0.041 14.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 XP_011271573.1 - 8.2e-07 29.2 0.5 0.045 13.8 0.0 3.0 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 XP_011271573.1 - 2.1e-06 27.8 0.0 0.034 14.1 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain NACHT PF05729.7 XP_011271573.1 - 1.2e-05 25.0 0.1 0.025 14.2 0.0 2.5 2 0 0 2 2 2 2 NACHT domain MMR_HSR1 PF01926.18 XP_011271573.1 - 1.3e-05 25.1 0.1 0.096 12.6 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 XP_011271573.1 - 1.7e-05 24.3 0.7 0.00058 19.3 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_33 PF13671.1 XP_011271573.1 - 2.3e-05 24.2 0.0 0.093 12.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 XP_011271573.1 - 4.2e-05 23.4 0.1 0.19 11.6 0.0 3.2 3 0 0 3 3 2 2 AAA domain cobW PF02492.14 XP_011271573.1 - 4.5e-05 22.9 2.2 0.12 11.7 0.1 2.5 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.1 XP_011271573.1 - 5e-05 23.3 3.1 0.054 13.4 0.1 3.2 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 XP_011271573.1 - 8.7e-05 22.8 3.6 0.075 13.3 0.0 3.1 4 0 0 4 4 2 2 AAA domain AAA_10 PF12846.2 XP_011271573.1 - 0.00027 20.4 4.2 0.14 11.5 0.2 2.5 2 0 0 2 2 2 2 AAA-like domain T2SE PF00437.15 XP_011271573.1 - 0.00031 19.7 0.2 0.37 9.6 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein SbcCD_C PF13558.1 XP_011271573.1 - 0.00048 19.9 0.2 2.5 8.0 0.1 3.3 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.1 XP_011271573.1 - 0.00063 19.3 2.3 0.33 10.4 0.0 2.8 3 0 0 3 3 2 2 AAA domain Arch_ATPase PF01637.13 XP_011271573.1 - 0.00076 19.2 0.0 1.4 8.5 0.0 2.6 2 0 0 2 2 2 2 Archaeal ATPase NTPase_1 PF03266.10 XP_011271573.1 - 0.001 18.8 1.2 1 9.0 0.1 3.8 4 0 0 4 4 4 1 NTPase Miro PF08477.8 XP_011271573.1 - 0.0011 19.5 0.0 3.3 8.2 0.0 2.9 2 0 0 2 2 2 0 Miro-like protein AAA_19 PF13245.1 XP_011271573.1 - 0.0014 18.3 0.3 0.86 9.4 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain Septin PF00735.13 XP_011271573.1 - 0.0024 16.9 0.1 0.2 10.6 0.0 2.3 2 0 0 2 2 2 1 Septin MobB PF03205.9 XP_011271573.1 - 0.0036 17.0 1.2 2.8 7.6 0.2 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B SRPRB PF09439.5 XP_011271573.1 - 0.0044 16.2 0.4 2.5 7.2 0.1 2.4 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit NB-ARC PF00931.17 XP_011271573.1 - 0.0053 15.6 0.0 1.9 7.2 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain AAA_30 PF13604.1 XP_011271573.1 - 0.0058 16.2 1.0 3.2 7.2 0.1 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 XP_011271573.1 - 0.0064 16.6 0.1 2.6 8.2 0.0 2.7 2 0 0 2 2 2 1 RNA helicase PRK PF00485.13 XP_011271573.1 - 0.0075 15.8 0.0 1.9 7.9 0.0 2.6 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family ATP_bind_1 PF03029.12 XP_011271573.1 - 0.012 15.2 2.1 1.9 7.9 0.1 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF87 PF01935.12 XP_011271573.1 - 0.014 15.2 2.2 0.14 11.9 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function DUF87 ABC_ATPase PF09818.4 XP_011271573.1 - 0.016 13.8 0.7 2.8 6.4 0.0 2.9 3 0 0 3 3 3 0 Predicted ATPase of the ABC class PduV-EutP PF10662.4 XP_011271573.1 - 0.019 14.4 0.9 4.5 6.7 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Pox_A32 PF04665.7 XP_011271573.1 - 0.021 14.1 1.6 0.83 8.8 0.1 2.5 2 0 0 2 2 2 0 Poxvirus A32 protein AAA PF00004.24 XP_011271573.1 - 0.022 14.9 2.4 1.7 8.8 0.0 3.5 3 2 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.9 XP_011271573.1 - 0.028 13.4 0.5 4.1 6.2 0.1 3.0 2 1 0 3 3 3 0 KAP family P-loop domain Zeta_toxin PF06414.7 XP_011271573.1 - 0.03 13.4 0.2 6.6 5.7 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin UPF0079 PF02367.12 XP_011271573.1 - 0.031 13.9 0.2 0.41 10.2 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_5 PF07728.9 XP_011271573.1 - 0.032 13.9 0.1 5.6 6.6 0.0 2.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ATP-synt_ab PF00006.20 XP_011271573.1 - 0.036 13.5 0.0 0.87 9.0 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain RecA PF00154.16 XP_011271573.1 - 0.12 11.4 0.1 2.6 6.9 0.0 2.2 2 0 0 2 2 2 0 recA bacterial DNA recombination protein FeoB_N PF02421.13 XP_011271573.1 - 0.26 10.5 2.9 7.3 5.8 0.1 2.9 3 0 0 3 3 3 0 Ferrous iron transport protein B ABC_tran PF00005.22 XP_011271574.1 - 7.4e-53 178.5 0.9 3.9e-26 91.9 0.1 2.7 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.19 XP_011271574.1 - 5.7e-32 110.5 38.8 1.2e-22 80.1 10.8 2.6 3 0 0 3 3 2 2 ABC-2 type transporter AAA_21 PF13304.1 XP_011271574.1 - 1.3e-14 54.9 31.9 3.8e-08 33.6 2.9 5.4 4 2 0 4 4 2 2 AAA domain SMC_N PF02463.14 XP_011271574.1 - 2.8e-13 49.6 4.0 8e-07 28.5 0.1 2.7 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 XP_011271574.1 - 2.3e-11 43.1 0.5 0.00011 21.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_15 PF13175.1 XP_011271574.1 - 1.3e-09 37.6 22.2 0.0067 15.5 0.4 4.8 3 2 2 5 5 5 4 AAA ATPase domain AAA_17 PF13207.1 XP_011271574.1 - 4.1e-08 34.0 0.0 0.011 16.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 XP_011271574.1 - 1.3e-07 31.7 1.3 0.013 15.6 0.1 3.2 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.1 XP_011271574.1 - 3.8e-07 29.5 2.4 0.0091 15.5 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.1 XP_011271574.1 - 4.7e-07 30.1 0.1 0.043 14.1 0.0 3.6 4 0 0 4 4 2 2 AAA domain AAA_25 PF13481.1 XP_011271574.1 - 6.8e-07 28.8 0.0 0.038 13.3 0.0 3.8 4 0 0 4 4 4 1 AAA domain AAA_16 PF13191.1 XP_011271574.1 - 9.8e-07 28.9 0.0 0.026 14.5 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.1 XP_011271574.1 - 2.4e-06 28.0 17.6 4.3e-06 27.2 0.1 3.8 3 1 0 3 3 2 1 AAA domain AAA_28 PF13521.1 XP_011271574.1 - 2.7e-06 27.4 0.0 0.069 13.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 XP_011271574.1 - 3e-06 26.9 0.0 0.0071 16.0 0.0 2.8 2 0 0 2 2 2 2 NACHT domain AAA_33 PF13671.1 XP_011271574.1 - 7.8e-06 25.8 0.0 0.11 12.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 XP_011271574.1 - 8.9e-06 25.6 0.1 0.065 13.1 0.0 3.6 3 0 0 3 3 3 2 AAA domain cobW PF02492.14 XP_011271574.1 - 9.9e-06 25.1 2.0 0.052 12.9 0.2 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 XP_011271574.1 - 1.5e-05 24.5 0.6 0.00096 18.6 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 XP_011271574.1 - 1.7e-05 24.7 2.2 0.069 13.1 0.1 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_24 PF13479.1 XP_011271574.1 - 2.3e-05 24.1 0.6 0.24 10.9 0.0 2.9 3 0 0 3 3 3 2 AAA domain T2SE PF00437.15 XP_011271574.1 - 2.6e-05 23.2 0.1 0.03 13.2 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_10 PF12846.2 XP_011271574.1 - 2.6e-05 23.8 2.7 0.1 12.0 0.3 2.6 2 0 0 2 2 2 2 AAA-like domain Arch_ATPase PF01637.13 XP_011271574.1 - 3.7e-05 23.5 0.1 0.096 12.3 0.0 2.5 2 0 0 2 2 2 2 Archaeal ATPase SbcCD_C PF13558.1 XP_011271574.1 - 8.9e-05 22.3 0.2 0.92 9.4 0.0 3.5 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit Miro PF08477.8 XP_011271574.1 - 0.00017 22.0 0.0 0.69 10.4 0.0 3.4 3 0 0 3 3 3 1 Miro-like protein Septin PF00735.13 XP_011271574.1 - 0.00031 19.8 0.1 0.091 11.7 0.0 2.6 2 0 0 2 2 2 1 Septin AAA_19 PF13245.1 XP_011271574.1 - 0.00041 20.0 0.1 0.24 11.1 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain MobB PF03205.9 XP_011271574.1 - 0.00047 19.8 0.9 0.42 10.3 0.1 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 XP_011271574.1 - 0.00082 19.5 0.3 2.4 8.3 0.0 3.5 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 XP_011271574.1 - 0.0011 18.5 0.1 0.019 14.5 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 XP_011271574.1 - 0.0019 18.3 0.0 1 9.5 0.0 2.9 2 0 0 2 2 2 1 RNA helicase NTPase_1 PF03266.10 XP_011271574.1 - 0.002 17.8 1.1 5.8 6.5 0.0 3.7 4 0 0 4 4 4 0 NTPase Pox_A32 PF04665.7 XP_011271574.1 - 0.0021 17.3 1.2 0.3 10.3 0.1 2.5 2 0 0 2 2 2 1 Poxvirus A32 protein NB-ARC PF00931.17 XP_011271574.1 - 0.0022 16.8 0.1 0.34 9.7 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain PRK PF00485.13 XP_011271574.1 - 0.0027 17.2 0.1 0.56 9.7 0.0 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.7 XP_011271574.1 - 0.0029 16.7 0.1 0.93 8.5 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin SRPRB PF09439.5 XP_011271574.1 - 0.0035 16.6 0.1 2.3 7.4 0.0 2.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 XP_011271574.1 - 0.0051 16.3 0.2 4.2 6.8 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.1 XP_011271574.1 - 0.007 15.9 0.3 2.5 7.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 XP_011271574.1 - 0.0092 15.7 0.0 7.9 6.2 0.0 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) KAP_NTPase PF07693.9 XP_011271574.1 - 0.01 14.8 1.5 0.62 8.9 0.1 3.1 2 1 0 3 3 3 0 KAP family P-loop domain ATP_bind_1 PF03029.12 XP_011271574.1 - 0.023 14.2 0.9 5.2 6.5 0.1 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein SRP54 PF00448.17 XP_011271574.1 - 0.036 13.5 1.5 0.92 8.9 0.1 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ABC_ATPase PF09818.4 XP_011271574.1 - 0.069 11.7 2.6 3.6 6.0 0.1 2.9 4 0 0 4 4 3 0 Predicted ATPase of the ABC class BatA PF07584.6 XP_011271574.1 - 0.074 13.2 0.2 5 7.3 0.0 3.0 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal DUF87 PF01935.12 XP_011271574.1 - 0.13 12.0 9.2 0.047 13.4 0.3 3.3 4 0 0 4 4 3 0 Domain of unknown function DUF87 ArgK PF03308.11 XP_011271574.1 - 0.27 9.9 0.4 2.1 7.0 0.0 2.3 3 0 0 3 3 2 0 ArgK protein Dynamin_N PF00350.18 XP_011271574.1 - 0.79 9.5 7.0 7.8 6.2 0.9 3.4 3 1 0 3 3 2 0 Dynamin family Mito_carr PF00153.22 XP_011271575.1 - 2.8e-73 241.6 0.9 1.9e-24 85.2 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 XP_011271575.1 - 0.017 15.2 9.1 0.16 12.1 1.2 4.1 3 1 0 3 3 3 0 EF-hand domain pair SAE2 PF08573.5 XP_011271576.1 - 4.5e-11 43.2 2.6 6.9e-11 42.7 0.1 2.6 2 0 0 2 2 2 1 DNA repair protein endonuclease SAE2/CtIP C-terminus SSV1_ORF_D-335 PF07935.6 XP_011271576.1 - 0.014 15.0 0.1 0.038 13.7 0.1 1.7 1 0 0 1 1 1 0 ORF D-335-like protein FlaC_arch PF05377.6 XP_011271576.1 - 0.092 12.6 5.2 0.15 11.9 0.4 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Bud13 PF09736.4 XP_011271577.1 - 1.8e-41 141.7 7.0 1.8e-41 141.7 4.8 3.1 2 1 0 3 3 3 1 Pre-mRNA-splicing factor of RES complex XRN_N PF03159.13 XP_011271578.1 - 2e-101 338.3 0.1 3.8e-101 337.4 0.0 1.5 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN_N PF03159.13 XP_011271579.1 - 3.1e-37 128.2 0.6 6e-21 74.9 0.0 2.9 2 1 1 3 3 3 2 XRN 5'-3' exonuclease N-terminus Nucleoporin_FG PF13634.1 XP_011271580.1 - 5.4e-49 165.1 167.2 5e-16 58.9 25.9 4.3 1 1 3 4 4 4 4 Nucleoporin FG repeat region DUF810 PF05664.6 XP_011271580.1 - 0.0047 15.2 0.3 0.0065 14.8 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF810) zf-C4H2 PF10146.4 XP_011271580.1 - 0.017 15.1 1.7 0.017 15.1 1.1 2.1 1 1 0 2 2 2 0 Zinc finger-containing protein Alpha-2-MRAP_C PF06401.6 XP_011271580.1 - 0.028 14.2 0.4 0.028 14.2 0.2 2.1 1 1 0 2 2 2 0 Alpha-2-macroglobulin RAP, C-terminal domain KxDL PF10241.4 XP_011271580.1 - 0.077 12.9 3.2 0.36 10.7 0.8 2.6 3 0 0 3 3 3 0 Uncharacterized conserved protein DUF1664 PF07889.7 XP_011271580.1 - 0.23 11.2 5.2 1.1 9.1 0.4 2.8 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) GspL_C PF12693.2 XP_011271580.1 - 3.3 7.4 15.8 4.4 7.0 10.6 1.4 1 1 0 1 1 1 0 GspL periplasmic domain DUF4201 PF13870.1 XP_011271580.1 - 6.3 6.1 10.2 9.2 5.6 7.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Pkinase PF00069.20 XP_011271582.1 - 8e-57 192.3 1.9 4.3e-56 189.9 1.3 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011271582.1 - 8e-23 80.8 0.0 1.2e-22 80.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 XP_011271582.1 - 0.0045 16.0 0.0 0.0078 15.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family LPP20 PF02169.11 XP_011271583.1 - 0.26 11.3 3.9 0.41 10.7 2.3 1.5 1 1 0 1 1 1 0 LPP20 lipoprotein zf-H2C2_2 PF13465.1 XP_011271584.1 - 1.5e-15 56.5 18.3 7e-08 32.3 1.8 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 XP_011271584.1 - 6.5e-11 41.9 24.5 0.00077 19.6 4.5 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 XP_011271584.1 - 9.7e-10 38.0 20.4 0.0016 18.5 3.5 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 XP_011271584.1 - 0.00017 21.3 13.4 0.0065 16.3 0.6 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger Elf1 PF05129.8 XP_011271584.1 - 0.0024 17.5 9.2 0.0031 17.1 2.1 2.6 1 1 1 2 2 2 1 Transcription elongation factor Elf1 like zf-C2H2_2 PF12756.2 XP_011271584.1 - 0.0066 16.5 10.1 1.6 8.8 0.9 3.7 1 1 2 3 3 3 1 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.1 XP_011271584.1 - 0.0068 16.0 0.8 0.0068 16.0 0.6 3.2 3 0 0 3 3 3 1 zinc-finger of a C2HC-type zf-Di19 PF05605.7 XP_011271584.1 - 0.0074 16.3 4.6 0.0074 16.3 3.2 2.1 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.1 XP_011271584.1 - 0.047 13.9 6.0 0.047 13.9 4.1 3.0 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Zn-ribbon_8 PF09723.5 XP_011271584.1 - 0.25 11.3 6.4 14 5.7 0.1 3.2 3 0 0 3 3 3 0 Zinc ribbon domain zf-C2H2_jaz PF12171.3 XP_011271584.1 - 0.43 10.7 13.2 0.17 12.0 1.4 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Zn_Tnp_IS1595 PF12760.2 XP_011271584.1 - 0.44 10.3 10.0 0.99 9.2 2.5 2.3 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zf-BED PF02892.10 XP_011271584.1 - 0.54 10.0 18.7 4.2 7.2 0.7 3.9 1 1 1 2 2 2 0 BED zinc finger zinc_ribbon_5 PF13719.1 XP_011271584.1 - 0.92 9.1 9.4 1.1 8.8 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 XP_011271584.1 - 1.5 8.6 9.6 1.9 8.2 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon domain zf-FCS PF06467.9 XP_011271584.1 - 2 8.0 9.0 8.4 6.1 0.2 2.7 1 1 1 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-CHY PF05495.7 XP_011271584.1 - 2.2 8.5 9.0 7.5 6.7 1.0 2.5 1 1 1 2 2 2 0 CHY zinc finger zf-AN1 PF01428.11 XP_011271584.1 - 3 7.7 18.0 0.95 9.3 1.7 3.3 2 1 1 3 3 3 0 AN1-like Zinc finger C1_4 PF07975.7 XP_011271584.1 - 3.2 7.8 10.2 39 4.3 2.9 3.1 1 1 1 2 2 2 0 TFIIH C1-like domain TFIIS_C PF01096.13 XP_011271584.1 - 8 6.1 8.1 23 4.7 0.2 3.1 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) Pro_CA PF00484.14 XP_011271585.1 - 5.1e-19 68.7 0.0 8e-19 68.1 0.0 1.3 1 1 0 1 1 1 1 Carbonic anhydrase Sugar_tr PF00083.19 XP_011271586.1 - 1.8e-45 155.3 21.8 2.4e-45 154.9 15.1 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 XP_011271586.1 - 6.3e-34 117.2 27.3 6.3e-34 117.2 19.0 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily ATG22 PF11700.3 XP_011271586.1 - 6.7e-07 28.1 26.6 0.0028 16.2 11.6 2.1 1 1 1 2 2 2 2 Vacuole effluxer Atg22 like DUF3852 PF12963.2 XP_011271586.1 - 2.7 8.0 9.7 0.086 12.8 0.3 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF3852) DUF605 PF04652.11 XP_011271587.1 - 9.2 5.5 27.1 11 5.3 18.8 1.1 1 0 0 1 1 1 0 Vta1 like Gtr1_RagA PF04670.7 XP_011271588.1 - 1.5e-69 233.6 0.6 2e-69 233.3 0.4 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 XP_011271588.1 - 0.0044 16.2 0.0 0.009 15.2 0.0 1.7 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 XP_011271588.1 - 0.022 14.0 0.1 0.059 12.5 0.0 1.7 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 XP_011271588.1 - 0.053 13.4 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain TYW3 PF02676.9 XP_011271589.1 - 9.6e-68 227.3 0.0 1.3e-67 226.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase TYW3 Muted PF14942.1 XP_011271589.1 - 0.074 12.9 9.0 0.12 12.2 6.2 1.3 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein U1snRNP70_N PF12220.3 XP_011271589.1 - 0.2 12.0 6.2 0.44 10.8 4.3 1.6 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal V_ATPase_I PF01496.14 XP_011271589.1 - 3.6 5.3 8.7 4.8 4.8 6.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family tRNA-synt_2 PF00152.15 XP_011271590.1 - 9.6e-83 277.7 0.4 1.8e-82 276.8 0.3 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 XP_011271590.1 - 2.7e-08 33.5 1.3 1.1e-07 31.5 0.7 2.1 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain RasGEF PF00617.14 XP_011271591.1 - 1.3e-63 214.1 1.2 4.3e-63 212.4 0.9 2.0 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 XP_011271591.1 - 6.8e-22 77.5 0.1 6.8e-22 77.5 0.1 3.6 3 1 0 3 3 3 1 RasGEF N-terminal motif SH3_9 PF14604.1 XP_011271591.1 - 3.6e-08 32.8 0.0 7.4e-08 31.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 XP_011271591.1 - 3.7e-08 32.6 0.1 8.5e-08 31.4 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 XP_011271591.1 - 2e-05 23.9 0.0 4.2e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain GRIP PF01465.15 XP_011271592.1 - 2.1e-16 59.1 1.4 5e-16 57.9 1.0 1.7 1 0 0 1 1 1 1 GRIP domain Filament PF00038.16 XP_011271592.1 - 2e-06 27.5 153.0 0.00048 19.7 6.2 5.5 2 2 3 5 5 5 4 Intermediate filament protein CENP-F_leu_zip PF10473.4 XP_011271592.1 - 9.3e-05 22.3 20.0 9.3e-05 22.3 13.8 10.3 2 2 8 10 10 10 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myosin_tail_1 PF01576.14 XP_011271592.1 - 0.0006 17.6 186.2 0.043 11.5 40.3 4.2 1 1 3 4 4 4 4 Myosin tail APG6 PF04111.7 XP_011271592.1 - 0.0011 18.1 22.7 0.0011 18.1 15.7 8.6 1 1 7 8 8 8 4 Autophagy protein Apg6 DUF641 PF04859.7 XP_011271592.1 - 0.014 15.1 1.3 0.014 15.1 0.9 11.0 6 3 4 11 11 11 0 Plant protein of unknown function (DUF641) IncA PF04156.9 XP_011271592.1 - 0.034 13.7 175.3 0.27 10.8 13.1 9.4 1 1 8 9 9 9 0 IncA protein Reo_sigmaC PF04582.7 XP_011271592.1 - 8.8 5.4 76.8 0.22 10.6 1.1 7.9 2 2 5 8 8 8 0 Reovirus sigma C capsid protein DivIC PF04977.10 XP_011271593.1 - 0.16 11.4 0.7 0.3 10.5 0.5 1.4 1 0 0 1 1 1 0 Septum formation initiator TFIIA PF03153.8 XP_011271593.1 - 0.37 10.6 19.8 0.57 10.0 13.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Polysacc_deac_1 PF01522.16 XP_011271594.1 - 1.1e-23 83.2 0.0 1.9e-23 82.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF619 PF04768.8 XP_011271595.1 - 1.1e-46 158.4 1.2 2.5e-46 157.2 0.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF619) BPL_LplA_LipB PF03099.14 XP_011271596.1 - 1.5e-18 66.9 0.0 3e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family UPF0086 PF01868.11 XP_011271597.1 - 3.9e-11 42.4 0.2 1.6e-10 40.4 0.0 2.1 2 1 0 2 2 2 1 Domain of unknown function UPF0086 Rho_Binding PF08912.6 XP_011271597.1 - 3.3 8.0 10.1 7.3 6.9 7.0 1.5 1 0 0 1 1 1 0 Rho Binding Adaptin_binding PF10199.4 XP_011271598.1 - 0.27 11.5 8.0 0.58 10.4 5.5 1.5 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 DUF3122 PF11320.3 XP_011271598.1 - 1.1 9.1 4.2 1.8 8.4 2.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3122) Ribosomal_S27e PF01667.12 XP_011271599.1 - 8e-29 98.9 0.9 1.1e-28 98.5 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein S27 TF_Zn_Ribbon PF08271.7 XP_011271599.1 - 0.00068 18.9 0.7 0.001 18.3 0.5 1.2 1 0 0 1 1 1 1 TFIIB zinc-binding IBR PF01485.16 XP_011271599.1 - 0.0011 18.7 0.4 0.0014 18.4 0.3 1.1 1 0 0 1 1 1 1 IBR domain zinc_ribbon_4 PF13717.1 XP_011271599.1 - 0.25 11.0 1.5 15 5.4 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 XP_011271599.1 - 0.29 10.7 1.5 16 5.1 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain DUF1712 PF08217.6 XP_011271600.1 - 0.059 11.6 0.2 0.061 11.5 0.1 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1712) dsrm PF00035.20 XP_011271602.1 - 0.013 16.0 1.2 0.093 13.3 0.3 2.5 2 0 0 2 2 2 0 Double-stranded RNA binding motif DUF605 PF04652.11 XP_011271602.1 - 1.5 8.1 21.4 2.5 7.4 14.8 1.4 1 0 0 1 1 1 0 Vta1 like DUF2683 PF10884.3 XP_011271603.1 - 2.1 8.3 7.0 0.8 9.6 1.1 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF2683) DNA_ligase_A_M PF01068.16 XP_011271604.1 - 1.9e-60 203.6 0.5 4.7e-60 202.4 0.0 1.9 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 XP_011271604.1 - 3.6e-54 183.2 0.6 7.3e-54 182.2 0.4 1.6 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 XP_011271604.1 - 1.4e-24 86.2 0.4 4.3e-24 84.7 0.0 2.1 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.1 XP_011271604.1 - 0.062 12.9 3.3 1.4 8.6 0.1 2.6 2 0 0 2 2 2 0 DNA ligase OB-like domain F-box-like PF12937.2 XP_011271605.1 - 0.00035 20.2 0.5 0.00083 19.0 0.4 1.7 1 0 0 1 1 1 1 F-box-like DUF3760 PF12586.3 XP_011271605.1 - 0.029 14.1 3.1 0.087 12.6 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3760) PMT PF02366.13 XP_011271606.1 - 1.6e-56 191.3 15.9 2.9e-56 190.5 11.0 1.4 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 XP_011271606.1 - 1.5e-23 83.3 0.2 2.3e-23 82.7 0.1 1.3 1 0 0 1 1 1 1 MIR domain Med21 PF11221.3 XP_011271607.1 - 5.4e-46 156.1 1.4 6.4e-46 155.9 1.0 1.1 1 0 0 1 1 1 1 Subunit 21 of Mediator complex PhoU_div PF01865.11 XP_011271607.1 - 0.024 13.8 0.0 0.035 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF47 Shugoshin_N PF07558.6 XP_011271607.1 - 0.088 12.5 3.1 0.21 11.3 2.2 1.6 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region DUF2408 PF10303.4 XP_011271607.1 - 0.19 11.8 2.2 0.58 10.2 1.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) ATP-synt_D PF01813.12 XP_011271608.1 - 0.00018 21.1 1.8 0.0014 18.2 1.2 1.9 1 1 0 1 1 1 1 ATP synthase subunit D P4Ha_N PF08336.6 XP_011271608.1 - 1.4 8.7 11.6 9.5 6.0 0.9 3.2 2 1 1 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region End3 PF12761.2 XP_011271608.1 - 1.9 8.1 11.5 0.26 10.9 3.9 2.2 1 1 2 3 3 3 0 Actin cytoskeleton-regulatory complex protein END3 Matrilin_ccoil PF10393.4 XP_011271608.1 - 3.9 6.9 7.3 0.14 11.5 0.3 2.2 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin PBD PF00786.23 XP_011271609.1 - 0.0026 18.1 2.8 0.0073 16.6 0.1 3.3 2 0 0 2 2 2 1 P21-Rho-binding domain RNase_P_p30 PF01876.11 XP_011271610.1 - 5.7e-49 165.2 0.4 8.6e-49 164.6 0.3 1.2 1 0 0 1 1 1 1 RNase P subunit p30 EthD PF07110.6 XP_011271611.1 - 0.07 14.0 0.0 0.077 13.9 0.0 1.2 1 0 0 1 1 1 0 EthD domain Methyltransf_29 PF03141.11 XP_011271611.1 - 0.11 10.8 3.2 0.12 10.6 2.2 1.0 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Pox_RNA_pol PF03293.9 XP_011271615.1 - 0.093 12.2 0.1 0.12 11.8 0.1 1.2 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase, 18 kD subunit MF_alpha_N PF05436.6 XP_011271615.1 - 0.2 11.3 0.7 0.29 10.8 0.5 1.3 1 1 0 1 1 1 0 Mating factor alpha precursor N-terminus Methyltransf_15 PF09445.5 XP_011271618.1 - 0.044 13.3 0.1 0.063 12.8 0.1 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase AA_permease PF00324.16 XP_011271619.1 - 1.1e-100 337.2 45.2 1.3e-100 337.0 31.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 XP_011271619.1 - 3.5e-39 134.5 48.9 4.8e-39 134.0 33.9 1.1 1 0 0 1 1 1 1 Amino acid permease YbgS PF13985.1 XP_011271622.1 - 0.00023 21.0 0.1 0.00028 20.7 0.1 1.1 1 0 0 1 1 1 1 YbgS-like protein eIF_4G1 PF12152.3 XP_011271626.1 - 0.059 13.2 1.3 0.8 9.6 0.1 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4G1 SSF PF00474.12 XP_011271632.1 - 9.1e-15 54.1 28.1 1.4e-14 53.5 19.4 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family DUF950 PF06106.6 XP_011271633.1 - 0.042 13.9 1.3 0.22 11.6 0.1 2.5 2 0 0 2 2 2 0 Staphylococcus protein of unknown function (DUF950) Apc4 PF12896.2 XP_011271634.1 - 2.7e-42 144.4 2.2 4.2e-42 143.8 1.5 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 Apc4_WD40 PF12894.2 XP_011271634.1 - 2.5e-07 30.1 0.0 8.6e-07 28.3 0.0 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain Inh PF02974.9 XP_011271634.1 - 0.009 15.5 0.0 0.04 13.4 0.0 2.1 1 1 1 2 2 2 1 Protease inhibitor Inh Syntaxin_2 PF14523.1 XP_011271634.1 - 0.011 15.7 0.1 0.049 13.6 0.1 2.1 1 0 0 1 1 1 0 Syntaxin-like protein SUI1 PF01253.17 XP_011271635.1 - 6.6e-14 51.4 1.0 1.7e-13 50.1 0.1 2.2 2 0 0 2 2 2 1 Translation initiation factor SUI1 SWIB PF02201.13 XP_011271635.1 - 5.3e-05 22.8 0.1 0.00015 21.3 0.1 1.7 1 0 0 1 1 1 1 SWIB/MDM2 domain PIG-S PF10510.4 XP_011271636.1 - 0.0063 15.2 1.9 0.047 12.3 0.2 2.1 1 1 1 2 2 2 2 Phosphatidylinositol-glycan biosynthesis class S protein Ribosomal_L1 PF00687.16 XP_011271637.1 - 2.9e-23 82.3 1.8 7.8e-23 80.9 0.3 2.0 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family Ribosomal_L34 PF00468.12 XP_011271637.1 - 3.7e-12 45.7 10.5 3.7e-12 45.7 7.2 1.9 2 0 0 2 2 2 1 Ribosomal protein L34 RNA_polI_A14 PF08203.6 XP_011271638.1 - 4e-20 71.8 2.2 5e-20 71.5 0.0 2.2 2 1 0 2 2 2 1 Yeast RNA polymerase I subunit RPA14 Dicty_REP PF05086.7 XP_011271638.1 - 0.13 10.0 8.9 0.15 9.8 6.2 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein RR_TM4-6 PF06459.7 XP_011271638.1 - 2.6 7.8 14.0 2.8 7.7 9.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Semialdhyde_dhC PF02774.13 XP_011271639.1 - 2.8e-43 147.9 0.0 5.5e-43 146.9 0.0 1.5 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 XP_011271639.1 - 1.2e-30 106.2 0.0 2.1e-30 105.5 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.11 XP_011271639.1 - 0.0056 17.2 0.0 0.016 15.7 0.0 1.9 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase DapB_N PF01113.15 XP_011271639.1 - 0.021 14.7 0.0 0.052 13.4 0.0 1.6 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Saccharop_dh PF03435.13 XP_011271639.1 - 0.036 13.0 0.0 0.062 12.2 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase Ldh_1_N PF00056.18 XP_011271639.1 - 0.042 13.6 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 XP_011271639.1 - 0.35 10.8 1.3 0.92 9.4 0.0 2.1 2 0 0 2 2 2 0 NADH(P)-binding Methyltransf_16 PF10294.4 XP_011271640.1 - 1.9e-14 53.5 0.1 3e-06 26.7 0.0 2.1 2 0 0 2 2 2 2 Putative methyltransferase T4_neck-protein PF11649.3 XP_011271640.1 - 0.12 11.6 0.0 0.26 10.5 0.0 1.5 2 0 0 2 2 2 0 Virus neck protein HIT PF01230.18 XP_011271641.1 - 5.4e-25 87.7 0.0 6.7e-25 87.4 0.0 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 XP_011271641.1 - 2e-08 34.4 0.1 3.6e-08 33.6 0.1 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 XP_011271641.1 - 0.0012 18.5 0.1 0.0025 17.4 0.1 1.5 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 DUF2578 PF10843.3 XP_011271642.1 - 3.2e-52 177.0 8.1 3.7e-52 176.8 5.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2578) Ribosomal_L7Ae PF01248.21 XP_011271644.1 - 2.4e-22 78.2 0.5 3.8e-22 77.6 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 XP_011271644.1 - 0.0082 15.9 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit Pop3 UCR_hinge PF02320.11 XP_011271645.1 - 2e-23 82.0 10.8 3.5e-23 81.3 7.5 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Sigma70_ner PF04546.8 XP_011271645.1 - 7.7e-05 22.4 14.2 9.3e-05 22.1 9.9 1.2 1 0 0 1 1 1 1 Sigma-70, non-essential region DUF2457 PF10446.4 XP_011271645.1 - 0.038 12.7 23.3 0.045 12.4 16.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF3381 PF11861.3 XP_011271645.1 - 0.16 11.4 18.0 4.9 6.6 9.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) DUF506 PF04720.7 XP_011271645.1 - 0.17 11.5 7.4 0.18 11.4 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF506) Nop14 PF04147.7 XP_011271645.1 - 0.2 9.5 19.6 0.22 9.4 13.6 1.0 1 0 0 1 1 1 0 Nop14-like family RNase_H2_suC PF08615.6 XP_011271645.1 - 0.57 10.0 3.7 0.83 9.4 2.5 1.3 1 0 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) UPF0203 PF05254.7 XP_011271645.1 - 0.65 9.8 9.9 1.2 8.9 2.3 2.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) Bd3614_N PF14442.1 XP_011271645.1 - 1.1 9.2 3.6 1.5 8.8 2.5 1.3 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal Utp14 PF04615.8 XP_011271645.1 - 1.3 7.0 13.5 1.5 6.8 9.3 1.0 1 0 0 1 1 1 0 Utp14 protein CDC45 PF02724.9 XP_011271645.1 - 1.8 6.4 13.0 2.1 6.2 9.0 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF3074 PF11274.3 XP_011271645.1 - 1.9 8.1 6.2 0.51 9.9 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3074) Daxx PF03344.10 XP_011271645.1 - 2.3 6.6 21.1 2.6 6.4 14.6 1.1 1 0 0 1 1 1 0 Daxx Family SAPS PF04499.10 XP_011271645.1 - 2.9 6.4 5.9 3.1 6.3 4.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein GCIP PF13324.1 XP_011271645.1 - 4.2 6.4 10.1 4.7 6.3 7.0 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Ycf1 PF05758.7 XP_011271645.1 - 4.8 4.7 10.1 5.1 4.6 7.0 1.0 1 0 0 1 1 1 0 Ycf1 RRN3 PF05327.6 XP_011271645.1 - 4.9 5.1 12.1 5.4 4.9 8.4 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CENP-T PF15511.1 XP_011271645.1 - 4.9 6.2 10.8 5.5 6.1 7.5 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T IncA PF04156.9 XP_011271645.1 - 5.9 6.4 10.7 6.6 6.2 7.4 1.2 1 0 0 1 1 1 0 IncA protein Med17 PF10156.4 XP_011271645.1 - 6.5 4.9 11.1 10 4.2 7.7 1.2 1 0 0 1 1 1 0 Subunit 17 of Mediator complex DUF2738 PF10927.3 XP_011271645.1 - 8.5 5.3 12.7 2.6 7.0 6.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2738) RRM_1 PF00076.17 XP_011271646.1 - 0.00074 19.1 0.1 0.0012 18.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 XP_011271646.1 - 0.031 14.2 0.0 0.051 13.5 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 XP_011271647.1 - 1.9e-15 56.2 0.6 2e-06 27.3 0.1 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 XP_011271647.1 - 5.1e-12 45.5 0.1 1.7e-07 31.0 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 XP_011271647.1 - 1.4e-08 34.4 0.3 4.8e-05 23.1 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2610 PF11020.3 XP_011271647.1 - 0.096 12.4 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2610) Ribosomal_L2_C PF03947.13 XP_011271648.1 - 8.9e-40 135.4 2.7 1.4e-39 134.8 1.9 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 XP_011271648.1 - 3.7e-13 49.2 0.3 8.7e-13 48.0 0.2 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain MFS_1 PF07690.11 XP_011271649.1 - 2.9e-24 85.4 26.4 1.2e-19 70.2 1.5 2.7 3 0 0 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.1 XP_011271649.1 - 1e-05 24.1 25.4 0.00033 19.1 5.1 2.9 2 1 0 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.19 XP_011271649.1 - 0.00081 18.0 8.6 0.00081 18.0 6.0 2.8 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.2 XP_011271649.1 - 0.11 12.3 0.0 0.11 12.3 0.0 4.2 3 1 1 4 4 4 0 MFS_1 like family SMC_N PF02463.14 XP_011271650.1 - 5e-65 218.8 24.6 2.3e-63 213.3 17.0 3.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 XP_011271650.1 - 9.6e-22 77.1 1.3 1.2e-20 73.6 0.2 2.9 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 XP_011271650.1 - 9.2e-13 48.9 23.9 9.2e-13 48.9 16.6 7.0 2 2 2 4 4 4 1 AAA domain AAA_21 PF13304.1 XP_011271650.1 - 2.1e-06 27.9 1.1 2.1e-06 27.9 0.8 5.4 2 2 1 3 3 3 2 AAA domain AAA_29 PF13555.1 XP_011271650.1 - 8.8e-05 21.9 0.1 8.8e-05 21.9 0.1 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain IncA PF04156.9 XP_011271650.1 - 0.0026 17.3 11.8 0.0026 17.3 8.2 7.4 2 2 4 6 6 6 1 IncA protein ABC_tran PF00005.22 XP_011271650.1 - 0.3 11.3 0.0 0.3 11.3 0.0 7.3 3 2 1 4 4 4 0 ABC transporter Myosin_tail_1 PF01576.14 XP_011271650.1 - 0.87 7.2 104.1 0.005 14.6 32.9 3.2 2 1 0 2 2 2 0 Myosin tail AA_permease_2 PF13520.1 XP_011271651.1 - 1.1e-55 188.8 40.7 1.4e-55 188.5 28.2 1.0 1 0 0 1 1 1 1 Amino acid permease PRCH PF03967.8 XP_011271652.1 - 0.01 15.3 1.7 0.035 13.6 1.2 1.9 1 0 0 1 1 1 0 Photosynthetic reaction centre, H-chain N-terminal region DASH_Dad3 PF08656.5 XP_011271653.1 - 6.9e-24 83.3 1.4 9.1e-24 82.9 1.0 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad3 DUF3452 PF11934.3 XP_011271653.1 - 0.038 13.3 0.5 0.044 13.1 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) DUF3763 PF12592.3 XP_011271653.1 - 0.059 13.0 0.3 0.58 9.8 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3763) Mga PF05043.8 XP_011271653.1 - 0.081 13.2 0.9 0.14 12.4 0.6 1.3 1 0 0 1 1 1 0 Mga helix-turn-helix domain WD40 PF00400.27 XP_011271654.1 - 7.8e-16 57.2 11.0 0.00025 20.7 0.0 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat Rax2 PF12768.2 XP_011271654.1 - 0.00099 18.3 0.3 0.0034 16.6 0.0 1.9 2 0 0 2 2 2 1 Cortical protein marker for cell polarity Lyase_1 PF00206.15 XP_011271655.1 - 3e-23 82.4 0.0 6.1e-23 81.4 0.0 1.5 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 XP_011271655.1 - 3.4e-17 62.2 0.0 1.4e-16 60.2 0.0 2.1 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus AsiA PF09010.5 XP_011271655.1 - 0.025 14.4 0.0 0.14 12.0 0.0 2.1 2 0 0 2 2 2 0 Anti-Sigma Factor A DUF1331 PF07048.6 XP_011271655.1 - 0.062 12.7 0.1 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1331) Mid2 PF04478.7 XP_011271656.1 - 6.4e-17 61.3 0.4 6.4e-17 61.3 0.3 4.6 1 1 2 3 3 3 1 Mid2 like cell wall stress sensor DUF2207 PF09972.4 XP_011271656.1 - 0.01 14.4 0.0 0.024 13.2 0.0 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Toxin_32 PF08120.6 XP_011271656.1 - 1.6 8.3 3.2 3.5 7.3 0.2 2.5 2 0 0 2 2 2 0 Tamulustoxin family Methyltransf_12 PF08242.7 XP_011271657.1 - 0.049 14.0 0.1 0.18 12.2 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain VP9 PF09625.5 XP_011271657.1 - 0.092 12.5 0.2 0.23 11.3 0.1 1.6 1 0 0 1 1 1 0 VP9 protein WG_beta_rep PF14903.1 XP_011271657.1 - 2 8.7 4.7 0.82 10.0 0.2 2.6 2 1 1 3 3 3 0 WG containing repeat Glyco_hydro_15 PF00723.16 XP_011271658.1 - 2.1e-53 181.5 0.2 2.7e-53 181.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Presenilin PF01080.12 XP_011271659.1 - 2.5 6.8 4.6 3.3 6.4 3.2 1.2 1 0 0 1 1 1 0 Presenilin Cyt-b5 PF00173.23 XP_011271660.1 - 2.9e-21 75.0 0.6 6e-21 74.0 0.0 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain ArfGap PF01412.13 XP_011271661.1 - 4e-42 142.7 1.1 4e-42 142.7 0.8 3.0 3 1 1 4 4 4 1 Putative GTPase activating protein for Arf PAT1 PF09770.4 XP_011271661.1 - 1.4 7.0 44.3 1.9 6.6 30.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Mito_carr PF00153.22 XP_011271662.1 - 2.5e-46 155.3 6.0 5.5e-16 58.0 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein FMO-like PF00743.14 XP_011271663.1 - 4.6e-28 97.7 0.0 5.4e-16 57.8 0.0 2.9 2 1 1 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 XP_011271663.1 - 6.2e-11 42.7 0.0 3e-09 37.2 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 XP_011271663.1 - 4.6e-07 29.0 0.2 1.5e-05 24.1 0.0 2.8 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 XP_011271663.1 - 9.2e-07 28.9 0.0 0.0033 17.3 0.0 2.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 XP_011271663.1 - 0.056 13.7 0.0 18 5.6 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_9 PF13454.1 XP_011271663.1 - 0.22 11.2 0.5 1.1 9.0 0.0 2.4 3 1 1 4 4 4 0 FAD-NAD(P)-binding DnaJ PF00226.26 XP_011271664.1 - 1.1e-25 89.1 1.7 2.8e-25 87.7 1.2 1.8 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 XP_011271664.1 - 1.2e-19 69.9 0.3 3.3e-17 62.1 0.0 3.3 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 XP_011271664.1 - 8.3e-15 54.5 18.2 1.3e-14 53.9 12.6 1.3 1 0 0 1 1 1 1 DnaJ central domain Cytochrom_c3_2 PF14537.1 XP_011271664.1 - 0.0028 17.9 5.2 0.0059 16.9 3.6 1.6 1 0 0 1 1 1 1 Cytochrome c3 HypA PF01155.14 XP_011271664.1 - 0.031 13.9 6.1 0.51 10.0 0.9 2.5 2 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family DUF1356 PF07092.7 XP_011271664.1 - 0.33 10.0 2.3 11 5.1 0.1 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1356) Securin PF04856.8 XP_011271665.1 - 3e-06 27.1 16.6 5.9e-06 26.1 11.4 1.6 1 1 0 1 1 1 1 Securin sister-chromatid separation inhibitor HTH_24 PF13412.1 XP_011271665.1 - 0.14 11.5 0.8 1.5 8.2 0.5 2.7 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding HTH_AsnC-type PF13404.1 XP_011271665.1 - 0.23 11.0 0.8 0.57 9.7 0.6 1.7 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain COesterase PF00135.23 XP_011271666.1 - 0.057 12.1 0.4 0.082 11.6 0.2 1.1 1 0 0 1 1 1 0 Carboxylesterase family Rsm22 PF09243.5 XP_011271667.1 - 1.5e-28 99.6 9.0 7.1e-10 38.3 5.9 4.5 2 2 0 3 3 3 3 Mitochondrial small ribosomal subunit Rsm22 HTH_3 PF01381.17 XP_011271667.1 - 0.014 15.2 0.8 0.051 13.4 0.1 2.3 2 0 0 2 2 2 0 Helix-turn-helix DapB_N PF01113.15 XP_011271668.1 - 0.016 15.1 0.0 0.029 14.2 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Sld5 PF05916.6 XP_011271669.1 - 4.9e-21 75.0 1.8 8.2e-21 74.3 1.3 1.3 1 0 0 1 1 1 1 GINS complex protein ArgK PF03308.11 XP_011271670.1 - 0.084 11.6 7.3 0.016 14.0 2.1 1.9 2 0 0 2 2 2 0 ArgK protein DUF836 PF05768.9 XP_011271671.1 - 1.1e-15 57.6 0.3 1.4e-15 57.3 0.2 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.1 XP_011271671.1 - 0.015 15.5 0.2 0.018 15.2 0.1 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain MecA PF05389.7 XP_011271672.1 - 0.078 12.5 0.1 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) MFS_1 PF07690.11 XP_011271673.1 - 4.6e-22 78.2 18.6 6.5e-22 77.7 12.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily CAP_GLY PF01302.20 XP_011271674.1 - 1.2e-14 53.7 0.1 2.1e-14 52.9 0.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain Histidinol_dh PF00815.15 XP_011271675.1 - 2.2e-186 619.4 2.9 3.5e-186 618.7 2.0 1.3 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.13 XP_011271675.1 - 5.5e-24 83.5 0.3 1.1e-23 82.6 0.2 1.6 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 XP_011271675.1 - 1.7e-11 44.2 2.3 2.3e-11 43.8 0.3 2.2 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase Glutaredoxin PF00462.19 XP_011271676.1 - 1e-16 60.6 0.0 1.5e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_9 PF14595.1 XP_011271676.1 - 0.00083 18.9 0.0 0.00089 18.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_3 PF13192.1 XP_011271676.1 - 0.0048 16.6 0.0 0.0064 16.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin domain GST_N_2 PF13409.1 XP_011271676.1 - 0.011 15.6 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 XP_011271676.1 - 0.021 15.0 0.0 0.031 14.4 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DUF836 PF05768.9 XP_011271676.1 - 0.07 13.4 0.0 0.094 12.9 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) SapB_1 PF05184.10 XP_011271676.1 - 0.21 11.4 0.8 9.3 6.2 0.1 2.6 2 0 0 2 2 2 0 Saposin-like type B, region 1 VHS PF00790.14 XP_011271677.1 - 3.1e-14 52.8 0.1 5.9e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 XP_011271677.1 - 9.5e-07 28.7 0.1 2.3e-06 27.4 0.1 1.7 1 0 0 1 1 1 1 GAT domain alpha-hel2 PF14456.1 XP_011271678.1 - 0.014 14.1 0.0 0.025 13.3 0.0 1.3 1 0 0 1 1 1 0 Alpha-helical domain 2 Spectrin PF00435.16 XP_011271678.1 - 0.23 11.7 9.8 0.95 9.7 1.0 2.6 2 0 0 2 2 2 0 Spectrin repeat IncA PF04156.9 XP_011271678.1 - 1.4 8.4 28.2 4.4 6.8 10.8 2.5 1 1 1 2 2 2 0 IncA protein Atg14 PF10186.4 XP_011271678.1 - 1.8 7.4 10.7 0.52 9.1 0.3 2.4 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Allexi_40kDa PF05549.6 XP_011271678.1 - 2.9 7.1 11.6 0.19 11.0 2.2 2.2 1 1 1 2 2 2 0 Allexivirus 40kDa protein Glyoxalase PF00903.20 XP_011271679.1 - 2.8e-28 98.4 0.5 6.6e-15 55.2 0.0 2.5 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 XP_011271679.1 - 1.8e-23 83.1 0.0 2e-12 47.6 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 XP_011271679.1 - 1.1e-12 47.9 0.0 3.3e-08 33.4 0.0 2.9 2 2 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CppA_N PF14506.1 XP_011271679.1 - 0.00074 19.1 0.0 0.53 9.9 0.0 2.5 2 0 0 2 2 2 2 CppA N-terminal Glyoxalase_3 PF13468.1 XP_011271679.1 - 0.015 15.2 0.0 0.11 12.3 0.0 2.4 1 1 1 2 2 2 0 Glyoxalase-like domain SelR PF01641.13 XP_011271680.1 - 1.8e-51 172.9 0.1 2.1e-51 172.7 0.1 1.0 1 0 0 1 1 1 1 SelR domain DZR PF12773.2 XP_011271680.1 - 0.0062 16.3 0.3 0.017 14.9 0.2 1.8 1 1 0 1 1 1 1 Double zinc ribbon Yippee-Mis18 PF03226.9 XP_011271680.1 - 0.14 12.2 1.5 1.1 9.3 1.0 2.1 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RA PF00788.18 XP_011271681.1 - 2.6e-15 56.6 0.0 5.4e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_2 PF07647.12 XP_011271681.1 - 2.2e-07 30.6 0.2 6.3e-07 29.1 0.1 1.9 1 1 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 XP_011271681.1 - 0.00018 21.6 0.1 0.00047 20.2 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ste50p-SAM PF09235.5 XP_011271681.1 - 0.00021 21.2 0.3 0.00021 21.2 0.2 2.3 3 0 0 3 3 3 1 Ste50p, sterile alpha motif MAP65_ASE1 PF03999.7 XP_011271681.1 - 4.2 5.8 15.5 5.9 5.3 10.8 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Thioredoxin PF00085.15 XP_011271682.1 - 4.7e-59 196.5 0.1 4.2e-29 100.2 0.0 3.6 3 0 0 3 3 3 3 Thioredoxin Thioredoxin_6 PF13848.1 XP_011271682.1 - 1.3e-39 135.9 4.6 2.5e-30 105.6 2.4 4.1 3 1 1 4 4 4 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 XP_011271682.1 - 1.9e-11 43.8 0.0 0.0002 21.3 0.0 2.8 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 XP_011271682.1 - 1.2e-10 41.5 2.5 0.00039 20.5 0.0 4.6 4 2 0 4 4 4 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 XP_011271682.1 - 4e-09 36.4 0.8 0.00076 19.5 0.0 4.0 4 0 0 4 4 4 2 Thioredoxin-like AhpC-TSA PF00578.16 XP_011271682.1 - 8.3e-07 28.7 0.2 0.015 14.9 0.0 2.9 3 0 0 3 3 3 2 AhpC/TSA family Calsequestrin PF01216.12 XP_011271682.1 - 7.9e-05 21.6 0.2 0.00016 20.5 0.1 1.5 1 0 0 1 1 1 1 Calsequestrin Thioredoxin_9 PF14595.1 XP_011271682.1 - 0.00056 19.4 0.2 0.29 10.6 0.0 2.8 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_3 PF13192.1 XP_011271682.1 - 0.0032 17.2 0.0 0.39 10.5 0.0 2.6 2 0 0 2 2 2 1 Thioredoxin domain Redoxin PF08534.5 XP_011271682.1 - 0.0042 16.6 0.5 0.17 11.3 0.0 2.7 3 0 0 3 3 3 1 Redoxin Thioredoxin_4 PF13462.1 XP_011271682.1 - 0.0057 16.6 0.4 9.2 6.2 0.0 3.8 3 1 1 4 4 4 1 Thioredoxin Glutaredoxin PF00462.19 XP_011271682.1 - 0.0077 16.1 1.2 0.85 9.6 0.1 3.1 2 1 0 2 2 2 1 Glutaredoxin Complex1_LYR PF05347.10 XP_011271683.1 - 5.3e-08 32.5 0.0 8.2e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 XP_011271683.1 - 2.6e-06 27.5 0.0 3.7e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 XP_011271683.1 - 9.7e-05 22.8 0.0 0.00012 22.5 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like RRP7 PF12923.2 XP_011271684.1 - 2.6e-31 108.3 14.6 2.6e-31 108.3 10.1 2.1 3 0 0 3 3 3 1 Ribosomal RNA-processing protein 7 (RRP7) DUF1985 PF09331.6 XP_011271684.1 - 0.64 9.8 8.5 0.39 10.5 4.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1985) GRASP55_65 PF04495.9 XP_011271685.1 - 2.9e-50 169.8 0.0 1.6e-40 138.3 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 XP_011271685.1 - 1.2e-05 25.1 0.0 0.13 12.1 0.0 2.3 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.19 XP_011271685.1 - 0.00021 21.4 0.1 0.81 9.9 0.0 3.0 3 0 0 3 3 3 2 PDZ domain (Also known as DHR or GLGF) Hexokinase_2 PF03727.11 XP_011271686.1 - 6.9e-80 267.7 0.0 1e-79 267.2 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 XP_011271686.1 - 1e-72 243.8 0.3 2.3e-72 242.6 0.1 1.6 2 0 0 2 2 2 1 Hexokinase WD40 PF00400.27 XP_011271687.1 - 7.7e-33 111.1 7.4 3.3e-07 29.9 0.0 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat PQQ_2 PF13360.1 XP_011271687.1 - 0.045 13.2 0.0 0.68 9.3 0.0 2.2 2 0 0 2 2 2 0 PQQ-like domain ATG22 PF11700.3 XP_011271688.1 - 4.5e-177 589.3 19.2 5.2e-177 589.1 13.3 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 XP_011271688.1 - 1.6e-07 30.3 36.9 1.4e-06 27.2 0.9 3.7 3 1 1 4 4 4 3 Major Facilitator Superfamily Tim17 PF02466.14 XP_011271689.1 - 5.3e-18 65.3 0.1 6.7e-18 64.9 0.1 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family La PF05383.12 XP_011271690.1 - 7.6e-19 67.2 1.2 2.6e-18 65.5 0.3 2.1 2 0 0 2 2 2 1 La domain Fe_dep_repress PF01325.14 XP_011271692.1 - 0.09 12.7 0.2 6.8 6.7 0.1 2.6 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain Mito_carr PF00153.22 XP_011271695.1 - 1.3e-59 197.9 4.4 9.2e-23 79.7 0.1 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein ApoO PF09769.4 XP_011271697.1 - 6.3e-41 139.7 0.1 1.6e-40 138.3 0.0 1.6 2 0 0 2 2 2 1 Apolipoprotein O DUF148 PF02520.12 XP_011271697.1 - 0.1 12.4 1.0 0.41 10.4 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF148 Baculo_PEP_C PF04513.7 XP_011271697.1 - 0.15 11.8 1.4 11 5.8 0.1 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF334 PF03904.8 XP_011271699.1 - 0.16 11.2 0.0 0.16 11.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF334) Kelch_3 PF13415.1 XP_011271700.1 - 2.1e-29 100.9 0.3 8.2e-06 25.8 0.1 6.1 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_5 PF13854.1 XP_011271700.1 - 2.4e-28 97.5 3.3 2.3e-06 27.4 0.0 5.7 5 0 0 5 5 5 5 Kelch motif Kelch_6 PF13964.1 XP_011271700.1 - 1.5e-24 85.0 6.3 3.5e-09 36.4 0.0 6.2 6 0 0 6 6 6 4 Kelch motif Kelch_4 PF13418.1 XP_011271700.1 - 6.3e-22 77.0 11.8 2.9e-05 23.7 0.1 6.6 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.10 XP_011271700.1 - 6.1e-16 57.4 9.0 0.00056 19.5 0.1 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_1 PF01344.20 XP_011271700.1 - 1.1e-15 56.8 4.6 2.1e-08 33.5 0.0 5.5 6 0 0 6 6 6 2 Kelch motif IncA PF04156.9 XP_011271700.1 - 0.29 10.7 0.0 0.29 10.7 0.0 4.2 3 1 1 4 4 4 0 IncA protein PilJ PF13675.1 XP_011271700.1 - 8.9 6.6 13.4 29 5.0 0.7 4.3 3 2 1 4 4 4 0 Type IV pili methyl-accepting chemotaxis transducer N-term MinE PF03776.9 XP_011271701.1 - 0.012 15.0 1.2 0.023 14.2 0.1 2.0 2 1 0 2 2 2 0 Septum formation topological specificity factor MinE Peptidase_S66 PF02016.10 XP_011271704.1 - 0.14 11.0 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 LD-carboxypeptidase Leu_leader PF08054.6 XP_011271704.1 - 7.3 6.3 6.2 28 4.4 0.2 2.4 2 0 0 2 2 2 0 Leucine operon leader peptide PP2C_2 PF13672.1 XP_011271705.1 - 6.2e-14 51.9 0.0 1e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 XP_011271705.1 - 2.1e-08 33.9 0.3 0.0025 17.2 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.7 XP_011271705.1 - 2.7e-07 30.4 0.0 3.6e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) DUF3139 PF11337.3 XP_011271710.1 - 0.58 10.4 4.2 0.51 10.6 1.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3139) Ribosomal_L28e PF01778.12 XP_011271712.1 - 8.7e-30 103.5 1.6 8.7e-30 103.5 1.1 1.9 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.9 XP_011271712.1 - 1.4e-29 102.1 19.1 1.4e-29 102.1 13.2 2.9 2 0 0 2 2 2 1 Mak16 protein C-terminal region CDC45 PF02724.9 XP_011271712.1 - 6.1 4.7 24.8 11 3.8 17.2 1.4 1 0 0 1 1 1 0 CDC45-like protein E1-E2_ATPase PF00122.15 XP_011271713.1 - 9.6e-19 67.3 0.1 1.6e-18 66.6 0.1 1.3 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 XP_011271713.1 - 1.3e-18 67.8 1.1 5.4e-18 65.8 0.8 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 XP_011271713.1 - 4.7e-13 50.0 2.6 2.7e-11 44.3 1.8 3.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 XP_011271713.1 - 2.9e-10 39.9 0.0 7.5e-10 38.6 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 XP_011271713.1 - 0.0016 18.0 0.3 0.016 14.7 0.1 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 XP_011271713.1 - 0.079 13.1 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Aldedh PF00171.17 XP_011271714.1 - 6.4e-20 70.9 2.2 5.8e-16 57.8 0.2 2.3 2 1 0 2 2 2 2 Aldehyde dehydrogenase family UvrD_C PF13361.1 XP_011271714.1 - 0.002 17.6 1.3 0.021 14.2 0.2 2.0 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Bet_v_1 PF00407.14 XP_011271714.1 - 0.049 13.2 0.2 0.47 10.0 0.1 2.3 2 1 0 2 2 2 0 Pathogenesis-related protein Bet v I family DUF1542 PF07564.6 XP_011271714.1 - 0.25 11.3 4.8 0.13 12.3 0.6 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) Copper-fist PF00649.13 XP_011271715.1 - 5.5e-06 25.4 2.8 5.5e-06 25.4 2.0 1.7 2 0 0 2 2 2 1 Copper fist DNA binding domain Nop14 PF04147.7 XP_011271715.1 - 0.024 12.6 9.4 0.031 12.2 6.5 1.1 1 0 0 1 1 1 0 Nop14-like family TFIIA PF03153.8 XP_011271715.1 - 0.089 12.6 16.8 0.13 12.0 11.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDC45 PF02724.9 XP_011271715.1 - 4.5 5.1 9.7 6.3 4.7 6.7 1.1 1 0 0 1 1 1 0 CDC45-like protein HSP70 PF00012.15 XP_011271716.1 - 2.5e-265 881.0 14.0 2.8e-265 880.9 9.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 XP_011271716.1 - 9.9e-15 53.9 5.5 4.8e-13 48.4 1.6 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 XP_011271716.1 - 0.011 15.3 0.0 0.033 13.7 0.0 1.8 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain DP PF08781.5 XP_011271716.1 - 0.069 12.8 2.8 0.77 9.4 0.0 2.4 2 0 0 2 2 2 0 Transcription factor DP Hydantoinase_A PF01968.13 XP_011271716.1 - 0.13 11.3 0.1 0.13 11.3 0.1 2.8 3 1 1 4 4 4 0 Hydantoinase/oxoprolinase DIOX_N PF14226.1 XP_011271717.1 - 5.2e-10 39.8 0.2 1.4e-09 38.5 0.0 1.9 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal Apc9 PF12856.2 XP_011271717.1 - 0.79 9.8 15.2 2.7 8.1 2.8 3.6 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 9 Hydrolase PF00702.21 XP_011271718.1 - 9.6e-22 78.4 0.0 2.5e-21 77.0 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 XP_011271718.1 - 4.3e-21 75.9 0.0 7.1e-21 75.2 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 XP_011271718.1 - 1.6e-17 63.2 0.1 3.6e-17 62.1 0.1 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 XP_011271718.1 - 2.1e-08 34.0 0.0 4.9e-07 29.6 0.0 2.6 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 XP_011271718.1 - 0.00029 20.4 1.1 0.00074 19.1 0.1 2.2 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 XP_011271718.1 - 0.033 13.4 0.1 0.078 12.2 0.0 1.6 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase Prenyltrans_2 PF13249.1 XP_011271718.1 - 0.22 11.9 0.0 1.4 9.3 0.0 2.1 2 0 0 2 2 2 0 Prenyltransferase-like Pkinase PF00069.20 XP_011271720.1 - 6.8e-53 179.4 0.0 8.3e-53 179.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011271720.1 - 2.6e-29 102.0 0.0 3.3e-29 101.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 XP_011271720.1 - 1.2e-06 27.7 0.0 2.5e-06 26.6 0.0 1.6 1 1 0 1 1 1 1 Kinase-like SHMT PF00464.14 XP_011271721.1 - 3.8e-201 667.6 0.1 4.5e-201 667.4 0.1 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.16 XP_011271721.1 - 2.1e-07 30.2 0.0 4.4e-07 29.1 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 XP_011271721.1 - 0.00022 20.0 0.0 0.00032 19.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V TRAP-gamma PF07074.7 XP_011271724.1 - 8.2 5.9 13.2 0.8 9.2 1.2 2.6 2 0 0 2 2 2 0 Translocon-associated protein, gamma subunit (TRAP-gamma) TSP_C PF05735.7 XP_011271726.1 - 0.065 12.8 0.0 0.07 12.6 0.0 1.2 1 0 0 1 1 1 0 Thrombospondin C-terminal region ChAPs PF09295.5 XP_011271729.1 - 3.6e-84 282.8 1.4 5.2e-84 282.3 0.9 1.2 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_11 PF13414.1 XP_011271729.1 - 0.04 13.5 0.1 0.61 9.7 0.1 2.7 2 1 1 3 3 3 0 TPR repeat TPR_2 PF07719.12 XP_011271729.1 - 0.08 12.9 0.0 9 6.4 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat SAPS PF04499.10 XP_011271730.1 - 1.7e-179 597.4 14.8 1.7e-179 597.4 10.2 4.4 3 2 0 3 3 3 1 SIT4 phosphatase-associated protein Mem_trans PF03547.13 XP_011271730.1 - 0.0029 15.9 4.3 0.0093 14.2 0.3 2.3 2 0 0 2 2 2 2 Membrane transport protein Arm PF00514.18 XP_011271730.1 - 0.039 13.7 0.1 1.3 8.9 0.0 2.9 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat PTPLA PF04387.9 XP_011271731.1 - 7.9e-47 158.7 9.1 1.2e-46 158.1 5.5 1.7 2 0 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA Ribosomal_L21p PF00829.16 XP_011271732.1 - 5.1e-06 26.5 0.0 9.1e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein ARL2_Bind_BART PF11527.3 XP_011271732.1 - 0.03 14.1 0.0 0.042 13.6 0.0 1.2 1 0 0 1 1 1 0 The ARF-like 2 binding protein BART Pkinase PF00069.20 XP_011271733.1 - 6.1e-66 222.2 0.0 1.2e-65 221.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011271733.1 - 4.3e-44 150.5 0.0 7.9e-44 149.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 XP_011271733.1 - 1.4e-08 34.1 0.0 1.6e-05 24.0 0.0 2.3 2 0 0 2 2 2 2 Kinase-like SAM_PNT PF02198.11 XP_011271733.1 - 0.031 14.0 0.4 0.08 12.7 0.3 1.6 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain APH PF01636.18 XP_011271733.1 - 0.038 13.7 0.0 0.067 12.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf-H2C2_2 PF13465.1 XP_011271734.1 - 3.5e-09 36.5 3.0 3.5e-09 36.5 2.1 4.1 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2 PF00096.21 XP_011271734.1 - 3.5e-09 36.4 14.7 4.1e-05 23.6 2.1 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 XP_011271734.1 - 1e-05 25.5 12.5 0.00064 19.8 1.2 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger DUF2225 PF09986.4 XP_011271734.1 - 0.025 14.0 3.6 0.39 10.1 0.2 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) PAT1 PF09770.4 XP_011271734.1 - 0.033 12.4 34.7 0.038 12.2 24.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-C2H2_6 PF13912.1 XP_011271734.1 - 0.043 13.7 5.2 0.44 10.5 0.7 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.7 XP_011271734.1 - 0.044 13.8 2.4 4.2 7.5 0.1 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.10 XP_011271734.1 - 0.17 11.6 6.8 0.094 12.4 1.3 2.5 1 1 1 2 2 2 0 BED zinc finger zf-Sec23_Sec24 PF04810.10 XP_011271734.1 - 0.5 9.9 2.9 0.82 9.2 0.2 2.2 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf-C2H2_2 PF12756.2 XP_011271734.1 - 0.83 9.8 7.8 2.8 8.0 0.5 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Acetyltransf_7 PF13508.1 XP_011271735.1 - 2.1e-07 31.0 0.0 3.8e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 XP_011271735.1 - 3.6e-06 26.8 0.0 9.2e-06 25.5 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 XP_011271735.1 - 4.2e-06 26.6 0.0 8.1e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 XP_011271735.1 - 0.003 17.2 0.1 0.0083 15.8 0.0 1.7 1 1 0 1 1 1 1 FR47-like protein DUF4217 PF13959.1 XP_011271736.1 - 0.042 13.4 0.0 0.56 9.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4217) PSP1 PF04468.7 XP_011271737.1 - 2.3e-33 114.0 0.8 2.3e-33 114.0 0.6 2.2 2 0 0 2 2 2 1 PSP1 C-terminal conserved region U3_assoc_6 PF08640.6 XP_011271738.1 - 1.9e-27 94.8 0.8 1.9e-27 94.8 0.5 3.0 3 0 0 3 3 3 1 U3 small nucleolar RNA-associated protein 6 NRDE-2 PF08424.5 XP_011271738.1 - 0.27 10.0 10.1 0.25 10.1 4.4 2.4 2 1 0 2 2 2 0 NRDE-2, necessary for RNA interference DUF1874 PF08960.5 XP_011271739.1 - 0.092 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1874) NUDIX_2 PF13869.1 XP_011271740.1 - 8.7e-33 113.2 0.7 9.4e-30 103.3 0.0 2.2 1 1 1 2 2 2 2 Nucleotide hydrolase YbgS PF13985.1 XP_011271740.1 - 1 9.3 7.6 0.74 9.7 0.7 2.4 2 0 0 2 2 2 0 YbgS-like protein ZZ PF00569.12 XP_011271741.1 - 4.4e-15 54.9 6.4 4.4e-15 54.9 4.5 1.7 2 0 0 2 2 2 1 Zinc finger, ZZ type SWIRM PF04433.12 XP_011271741.1 - 2.5e-09 37.1 1.1 1.2e-08 34.9 0.1 2.5 2 0 0 2 2 2 1 SWIRM domain Myb_DNA-binding PF00249.26 XP_011271741.1 - 1.2e-07 31.6 0.1 5.8e-07 29.4 0.0 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 XP_011271741.1 - 0.0022 18.0 1.2 0.0066 16.5 0.1 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain Ribosomal_S17e PF00833.13 XP_011271742.1 - 3.2e-56 188.3 0.8 3.8e-56 188.1 0.5 1.0 1 0 0 1 1 1 1 Ribosomal S17 UPF0262 PF06793.7 XP_011271742.1 - 0.017 14.8 0.1 0.043 13.5 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0262) CcdB PF01845.12 XP_011271742.1 - 0.024 14.5 0.1 0.21 11.5 0.0 2.0 2 0 0 2 2 2 0 CcdB protein Cryptochrome_C PF12546.3 XP_011271742.1 - 0.085 13.5 0.1 0.13 12.9 0.1 1.4 1 0 0 1 1 1 0 Blue/Ultraviolet sensing protein C terminal ECM11 PF15463.1 XP_011271745.1 - 3.1e-10 40.4 0.9 3.1e-10 40.4 0.6 2.2 1 1 1 2 2 2 1 Extracellular mutant protein 11 Metallophos PF00149.23 XP_011271746.1 - 6.5e-09 35.4 8.2 6.5e-09 35.4 5.7 2.8 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 XP_011271746.1 - 0.00046 20.0 0.1 0.0054 16.5 0.0 2.4 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain DUF3439 PF11921.3 XP_011271747.1 - 0.53 10.0 7.4 0.37 10.5 2.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Pkinase PF00069.20 XP_011271748.1 - 1e-70 237.8 0.0 1.6e-70 237.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011271748.1 - 3.2e-33 114.9 0.0 4.8e-33 114.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 XP_011271748.1 - 1.6e-08 34.8 1.1 1.6e-08 34.8 0.7 4.1 4 0 0 4 4 4 1 Protein kinase C terminal domain Kinase-like PF14531.1 XP_011271748.1 - 0.00066 18.7 0.0 0.0013 17.7 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 XP_011271748.1 - 0.23 11.1 0.0 0.37 10.4 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.20 XP_011271749.1 - 3e-77 259.2 0.0 7.3e-77 258.0 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011271749.1 - 1.3e-39 135.8 0.0 2.3e-39 135.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 XP_011271749.1 - 0.0049 16.6 0.0 0.11 12.2 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 XP_011271749.1 - 0.0064 15.4 0.0 0.013 14.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Ras PF00071.17 XP_011271750.1 - 1.7e-46 157.5 0.0 2.6e-46 156.9 0.0 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 XP_011271750.1 - 1.5e-16 60.9 1.9 2.1e-16 60.4 0.0 2.1 2 1 0 2 2 2 1 Miro-like protein Arf PF00025.16 XP_011271750.1 - 0.00015 21.0 0.0 0.00025 20.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_24 PF13479.1 XP_011271750.1 - 0.0015 18.1 0.0 0.003 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 XP_011271750.1 - 0.054 13.4 1.0 0.2 11.6 0.0 2.4 2 1 1 3 3 3 0 50S ribosome-binding GTPase F-box-like PF12937.2 XP_011271751.1 - 3.9e-05 23.2 0.9 0.00011 21.9 0.0 2.3 2 0 0 2 2 2 1 F-box-like LRR_8 PF13855.1 XP_011271751.1 - 0.00072 19.2 21.7 0.24 11.2 0.1 6.0 5 1 0 6 6 6 4 Leucine rich repeat PRANC PF09372.5 XP_011271751.1 - 0.035 14.0 0.1 0.035 14.0 0.0 3.7 3 1 1 4 4 4 0 PRANC domain Myosin_head PF00063.16 XP_011271752.1 - 1e-249 830.2 14.4 1e-249 830.2 10.0 4.1 4 1 0 4 4 4 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 XP_011271752.1 - 7.2e-07 27.3 217.7 0.00031 18.6 36.0 6.9 1 1 4 5 5 5 4 Myosin tail CCDC155 PF14662.1 XP_011271752.1 - 0.0022 17.6 27.9 0.0022 17.6 19.3 9.6 2 2 6 9 9 9 1 Coiled-coil region of CCDC155 AAA_19 PF13245.1 XP_011271752.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain Reo_sigmaC PF04582.7 XP_011271752.1 - 6.6 5.8 76.0 0.24 10.5 5.0 7.9 3 2 5 8 8 8 0 Reovirus sigma C capsid protein Peptidase_M16_C PF05193.16 XP_011271753.1 - 1e-40 139.3 0.0 3.1e-40 137.7 0.0 1.8 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 XP_011271753.1 - 5.5e-37 126.8 0.0 2e-36 125.0 0.0 1.8 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) GHMP_kinases_N PF00288.21 XP_011271754.1 - 2.8e-12 46.4 0.0 6.1e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 XP_011271754.1 - 5.4e-05 23.3 0.0 0.00011 22.3 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal ATP-synt_C PF00137.16 XP_011271755.1 - 3e-29 100.6 26.4 2.6e-17 62.4 6.3 2.2 2 0 0 2 2 2 2 ATP synthase subunit C Sensor_TM1 PF13755.1 XP_011271755.1 - 0.068 12.6 0.9 1.4 8.4 0.1 2.4 2 0 0 2 2 2 0 Sensor N-terminal transmembrane domain PC_rep PF01851.17 XP_011271756.1 - 9.4e-13 47.6 19.6 0.0055 16.8 0.0 9.5 11 0 0 11 11 11 4 Proteasome/cyclosome repeat HEAT_2 PF13646.1 XP_011271756.1 - 0.00062 20.0 0.2 0.14 12.4 0.0 3.6 3 0 0 3 3 3 1 HEAT repeats TipAS PF07739.8 XP_011271756.1 - 0.0043 17.3 2.1 0.0043 17.3 1.5 2.3 2 0 0 2 2 2 1 TipAS antibiotic-recognition domain DPPIV_N PF00930.16 XP_011271757.1 - 1.2e-100 336.5 4.8 1.9e-100 335.8 3.4 1.3 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 XP_011271757.1 - 2.7e-54 183.6 0.3 4.2e-54 182.9 0.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 XP_011271757.1 - 5.7e-07 29.3 0.0 1.2e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 XP_011271757.1 - 1.2e-05 24.8 0.0 3.2e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.2 XP_011271757.1 - 0.001 19.0 0.0 0.012 15.4 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 XP_011271757.1 - 0.0017 17.8 0.0 0.98 8.8 0.0 2.4 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase DLH PF01738.13 XP_011271757.1 - 0.033 13.4 0.0 0.26 10.5 0.0 2.0 1 1 0 1 1 1 0 Dienelactone hydrolase family Peptidase_S15 PF02129.13 XP_011271757.1 - 0.05 13.0 0.2 0.53 9.6 0.1 2.2 1 1 1 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.8 XP_011271757.1 - 0.15 11.6 0.0 0.33 10.5 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold FAR1 PF03101.10 XP_011271758.1 - 3.3e-06 27.5 2.1 3.3e-06 27.5 1.5 2.9 3 1 0 3 3 3 1 FAR1 DNA-binding domain PAT1 PF09770.4 XP_011271758.1 - 0.033 12.4 81.0 0.021 13.1 26.8 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Pkinase PF00069.20 XP_011271759.1 - 4.5e-68 229.2 0.0 4.5e-68 229.2 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011271759.1 - 6.9e-31 107.2 0.0 6.9e-31 107.2 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 XP_011271759.1 - 0.067 12.9 5.2 0.19 11.3 0.1 2.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family Baculo_PP31 PF05311.6 XP_011271759.1 - 0.11 11.7 5.6 0.18 11.0 3.9 1.3 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) PAT1 PF09770.4 XP_011271759.1 - 0.91 7.6 50.5 1.3 7.2 35.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Tim54 PF11711.3 XP_011271759.1 - 0.98 7.9 11.0 1.4 7.4 7.6 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Med15 PF09606.5 XP_011271759.1 - 5.9 4.9 54.5 7.9 4.5 37.8 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PIF1 PF05970.9 XP_011271760.1 - 2.2e-53 181.5 0.3 9.7e-43 146.4 0.0 2.3 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 XP_011271760.1 - 3.6e-14 52.7 0.0 7.4e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.9 XP_011271760.1 - 1.5e-06 26.2 0.1 1.9e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 Helicase AAA_22 PF13401.1 XP_011271760.1 - 6.2e-06 26.3 0.0 1.5e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 XP_011271760.1 - 5.8e-05 22.7 0.7 0.00017 21.2 0.5 1.8 1 0 0 1 1 1 1 Part of AAA domain Viral_helicase1 PF01443.13 XP_011271760.1 - 0.00015 21.4 0.4 0.37 10.2 0.0 3.7 2 2 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.9 XP_011271760.1 - 0.00052 19.7 0.6 0.0029 17.2 0.1 2.3 1 1 1 2 2 2 1 Helicase UvrD_C_2 PF13538.1 XP_011271760.1 - 0.00077 19.5 0.0 0.004 17.2 0.0 2.1 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain T2SE PF00437.15 XP_011271760.1 - 0.003 16.4 0.0 0.0056 15.6 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.1 XP_011271760.1 - 0.0032 17.4 0.0 0.011 15.7 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain DUF2075 PF09848.4 XP_011271760.1 - 0.0052 15.8 0.1 0.01 14.8 0.1 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA PF00004.24 XP_011271760.1 - 0.0054 16.9 0.0 0.014 15.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 XP_011271760.1 - 0.013 15.2 0.4 0.058 13.1 0.1 2.2 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 XP_011271760.1 - 0.016 15.3 0.0 0.17 12.0 0.0 2.6 2 1 0 2 2 2 0 RNA helicase PhoH PF02562.11 XP_011271760.1 - 0.019 14.2 0.0 0.052 12.7 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.1 XP_011271760.1 - 0.034 13.5 0.0 0.082 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 XP_011271760.1 - 0.035 13.8 0.2 0.4 10.3 0.1 2.3 1 1 0 1 1 1 0 Archaeal ATPase TrwB_AAD_bind PF10412.4 XP_011271760.1 - 0.043 12.4 0.0 0.073 11.6 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain KaiC PF06745.8 XP_011271760.1 - 0.11 11.6 0.4 0.24 10.4 0.0 1.7 2 0 0 2 2 2 0 KaiC MFS_1 PF07690.11 XP_011271761.1 - 1.6e-42 145.4 31.7 1.6e-42 145.4 22.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 XP_011271761.1 - 4.5e-13 48.5 9.3 4.5e-13 48.5 6.4 2.7 1 1 1 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 XP_011271761.1 - 2.2e-05 22.8 2.7 4e-05 22.0 1.9 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ESSS PF10183.4 XP_011271761.1 - 0.059 13.7 0.2 5.9 7.3 0.0 3.2 3 0 0 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) MFS_1 PF07690.11 XP_011271762.1 - 1.2e-37 129.4 39.6 1.2e-37 129.4 27.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 XP_011271762.1 - 2.2e-09 36.4 36.7 7.7e-09 34.6 25.4 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 XP_011271762.1 - 0.00021 19.6 4.2 0.00021 19.6 2.9 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TPR_19 PF14559.1 XP_011271763.1 - 0.023 15.0 0.0 0.3 11.4 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Sirohm_synth_C PF14823.1 XP_011271763.1 - 0.047 13.0 0.1 0.22 10.8 0.1 2.2 1 1 0 1 1 1 0 Sirohaem biosynthesis protein C-terminal Bul1_N PF04425.7 XP_011271765.1 - 9.6e-110 367.1 7.1 9.6e-110 367.1 4.9 3.1 4 0 0 4 4 4 1 Bul1 N terminus Bul1_C PF04426.7 XP_011271765.1 - 8.4e-24 84.1 14.2 1.6e-16 60.3 1.4 3.8 3 2 2 5 5 5 2 Bul1 C terminus UPF0278 PF08745.6 XP_011271765.1 - 0.039 13.1 0.0 1.5 8.0 0.0 2.3 2 0 0 2 2 2 0 UPF0278 family Bul1_N PF04425.7 XP_011271766.1 - 3.9e-111 371.7 0.7 3.9e-111 371.7 0.5 2.7 2 1 1 3 3 3 1 Bul1 N terminus Bul1_C PF04426.7 XP_011271766.1 - 5.1e-31 107.8 20.8 1.4e-16 60.5 1.2 3.2 2 1 1 3 3 3 2 Bul1 C terminus PAT1 PF09770.4 XP_011271767.1 - 0.03 12.6 29.2 0.035 12.3 20.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 XP_011271767.1 - 0.13 11.5 19.8 0.16 11.3 13.7 1.0 1 0 0 1 1 1 0 Vta1 like Bul1_N PF04425.7 XP_011271768.1 - 1.5e-07 30.3 2.5 4.2e-07 28.8 0.8 2.1 2 0 0 2 2 2 1 Bul1 N terminus Arrestin_N PF00339.24 XP_011271768.1 - 0.028 14.2 0.0 0.3 10.8 0.0 3.0 1 1 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain ubiquitin PF00240.18 XP_011271769.1 - 8.1e-20 69.9 0.1 2.8e-19 68.2 0.0 1.9 1 0 0 1 1 1 1 Ubiquitin family TAF8_C PF10406.4 XP_011271769.1 - 1.4e-17 63.4 0.6 5.3e-17 61.5 0.1 2.4 2 0 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term Rad60-SLD PF11976.3 XP_011271769.1 - 9.3e-07 28.4 0.1 9.3e-07 28.4 0.1 2.6 3 0 0 3 3 3 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.26 XP_011271769.1 - 1.2e-06 28.2 1.7 1.3e-06 28.0 0.0 2.1 2 0 0 2 2 2 1 UBA/TS-N domain DUF2407 PF10302.4 XP_011271769.1 - 6.2e-06 26.3 0.7 0.00017 21.7 0.0 3.1 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Bromo_TP PF07524.8 XP_011271769.1 - 0.00078 19.1 0.0 0.0015 18.2 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated Rad60-SLD_2 PF13881.1 XP_011271769.1 - 0.0034 17.2 0.0 0.011 15.6 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like NIF PF03031.13 XP_011271770.1 - 1.7e-27 96.0 0.0 6.1e-27 94.2 0.0 1.9 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase BRCT PF00533.21 XP_011271770.1 - 2.5e-12 46.7 0.1 9.1e-12 44.9 0.1 2.1 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 XP_011271770.1 - 3.5e-08 33.1 0.2 8.5e-08 31.9 0.2 1.7 1 0 0 1 1 1 1 twin BRCT domain Biotin_lipoyl PF00364.17 XP_011271770.1 - 0.00094 18.7 0.2 0.045 13.4 0.1 2.5 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 XP_011271770.1 - 0.014 15.0 0.2 0.045 13.4 0.1 1.8 1 0 0 1 1 1 0 Biotin-lipoyl like HlyD_3 PF13437.1 XP_011271770.1 - 0.038 14.3 0.6 0.17 12.2 0.0 2.4 3 0 0 3 3 3 0 HlyD family secretion protein DUF4613 PF15390.1 XP_011271770.1 - 0.59 8.2 6.6 0.98 7.5 4.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) HTH_WhiA PF02650.9 XP_011271770.1 - 4.6 7.6 9.4 40 4.6 2.8 3.4 3 1 0 3 3 3 0 WhiA C-terminal HTH domain EMP24_GP25L PF01105.19 XP_011271770.1 - 7.8 6.1 10.5 3.8 7.2 0.1 3.2 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD PGM_PMM_I PF02878.11 XP_011271771.1 - 2e-33 114.8 0.0 3.8e-33 113.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 XP_011271771.1 - 1.4e-21 76.7 0.0 2.9e-21 75.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 XP_011271771.1 - 7.6e-15 54.9 0.0 1.5e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 XP_011271771.1 - 2.3e-06 27.4 0.0 6.1e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Anp1 PF03452.9 XP_011271772.1 - 1.2e-118 395.1 0.0 1.6e-118 394.7 0.0 1.1 1 0 0 1 1 1 1 Anp1 Asp PF00026.18 XP_011271773.1 - 8.3e-55 186.2 6.2 1.3e-54 185.6 4.3 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 XP_011271773.1 - 2.5e-09 37.3 1.6 3.6e-09 36.7 0.0 2.1 3 0 0 3 3 3 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 XP_011271773.1 - 1.2e-07 31.4 0.2 1.2e-05 24.9 0.0 2.8 2 1 1 3 3 3 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 XP_011271773.1 - 0.012 16.1 0.5 2.2 8.8 0.0 3.0 2 1 0 2 2 2 0 Aspartyl protease gag-asp_proteas PF13975.1 XP_011271773.1 - 0.13 12.0 0.0 26 4.7 0.0 2.6 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease MFS_1 PF07690.11 XP_011271774.1 - 9.1e-42 143.0 60.9 2.8e-37 128.2 34.3 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 XP_011271774.1 - 9.8e-06 24.3 32.9 0.00034 19.3 7.9 2.9 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.11 XP_011271775.1 - 5.4e-32 110.8 50.5 5.4e-32 110.8 35.0 2.7 1 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 XP_011271775.1 - 0.0037 15.8 35.8 0.021 13.4 8.4 2.7 2 1 0 3 3 3 2 Sugar (and other) transporter RRM_1 PF00076.17 XP_011271776.1 - 9.4e-15 54.0 8.6 0.00031 20.3 0.4 5.5 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM PF10378.4 XP_011271776.1 - 3e-14 52.3 5.4 3e-14 52.3 3.7 3.5 3 0 0 3 3 3 1 Putative RRM domain RRM_6 PF14259.1 XP_011271776.1 - 4.1e-13 49.1 4.1 0.00011 22.1 0.0 5.5 5 0 0 5 5 5 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 XP_011271776.1 - 5.8e-13 48.4 5.0 3.1e-05 23.7 0.3 5.1 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nab6_mRNP_bdg PF10567.4 XP_011271776.1 - 8.8e-13 47.9 15.2 8.8e-13 47.9 10.5 4.5 3 2 0 3 3 3 1 RNA-recognition motif Fungal_trans PF04082.13 XP_011271777.1 - 8.9e-37 126.3 4.8 3.5e-36 124.4 3.3 2.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 XP_011271777.1 - 1.8e-10 40.5 11.7 3.1e-10 39.7 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sec39 PF08314.6 XP_011271778.1 - 7.9e-75 252.1 38.3 2.1e-74 250.7 26.5 1.6 1 1 0 1 1 1 1 Secretory pathway protein Sec39 PIF1 PF05970.9 XP_011271779.1 - 8.8e-69 232.1 2.3 1.9e-54 185.0 0.3 2.4 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 XP_011271779.1 - 1.5e-14 54.0 0.0 2.7e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 XP_011271779.1 - 1.2e-06 28.6 0.0 4.5e-06 26.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 XP_011271779.1 - 4.5e-05 23.0 0.5 0.12 11.8 0.0 3.6 3 1 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA PF00004.24 XP_011271779.1 - 8.1e-05 22.8 0.1 0.00045 20.4 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) UvrD_C_2 PF13538.1 XP_011271779.1 - 0.00033 20.7 0.0 0.0038 17.3 0.0 2.5 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 XP_011271779.1 - 0.00061 19.4 0.1 0.0014 18.3 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain Herpes_Helicase PF02689.9 XP_011271779.1 - 0.00073 17.4 0.2 0.02 12.6 0.0 2.3 2 0 0 2 2 2 1 Helicase PhoH PF02562.11 XP_011271779.1 - 0.01 15.1 0.0 0.039 13.1 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein AAA_16 PF13191.1 XP_011271779.1 - 0.048 13.6 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 XP_011271779.1 - 0.052 13.0 0.1 0.1 12.0 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.1 XP_011271779.1 - 0.066 12.7 0.0 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.7 XP_011271779.1 - 0.17 11.5 1.0 0.66 9.6 0.0 2.5 3 0 0 3 3 3 0 NACHT domain OGG_N PF07934.7 XP_011271780.1 - 3e-19 69.1 0.3 1.1e-18 67.3 0.1 1.9 2 0 0 2 2 2 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 XP_011271780.1 - 8.9e-14 51.6 0.0 1.7e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein MRP-L47 PF06984.8 XP_011271781.1 - 3.7e-24 84.4 1.2 9.7e-24 83.0 0.8 1.7 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) LSM PF01423.17 XP_011271782.1 - 3.9e-08 32.7 0.0 6.9e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 LSM domain Fe_dep_repress PF01325.14 XP_011271782.1 - 0.016 15.1 0.0 0.023 14.6 0.0 1.2 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain cNMP_binding PF00027.24 XP_011271783.1 - 1.5e-42 143.2 0.1 2e-18 65.9 0.0 4.8 5 0 0 5 5 5 3 Cyclic nucleotide-binding domain Patatin PF01734.17 XP_011271783.1 - 1.7e-18 67.2 9.9 3.6e-18 66.2 4.0 3.2 2 1 0 2 2 2 1 Patatin-like phospholipase Myb_DNA-bind_4 PF13837.1 XP_011271783.1 - 0.063 13.4 0.7 0.34 11.0 0.1 2.4 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain SURF4 PF02077.10 XP_011271784.1 - 7.9e-93 310.6 10.9 9.2e-93 310.4 7.5 1.0 1 0 0 1 1 1 1 SURF4 family DUF2207 PF09972.4 XP_011271784.1 - 6.1 5.2 17.3 0.082 11.4 0.9 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) ABC_membrane PF00664.18 XP_011271785.1 - 1.2e-63 215.1 33.6 4.8e-36 124.5 9.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 XP_011271785.1 - 1.1e-48 165.0 2.9 7.3e-30 104.0 0.1 3.8 3 1 0 3 3 3 2 ABC transporter AAA_29 PF13555.1 XP_011271785.1 - 4.2e-08 32.5 1.6 0.00026 20.4 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 XP_011271785.1 - 5.2e-08 32.3 10.7 0.0012 18.0 1.2 4.3 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 XP_011271785.1 - 9.2e-08 32.9 0.2 0.018 15.8 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 XP_011271785.1 - 9.3e-08 32.3 22.6 7.5e-07 29.3 0.1 5.7 4 2 0 5 5 5 2 AAA domain AAA_16 PF13191.1 XP_011271785.1 - 1.9e-05 24.7 0.7 0.026 14.5 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 XP_011271785.1 - 3.8e-05 22.9 0.4 0.093 11.9 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 T2SE PF00437.15 XP_011271785.1 - 0.00054 18.9 0.1 0.013 14.3 0.1 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein MMR_HSR1 PF01926.18 XP_011271785.1 - 0.0011 18.8 2.6 0.46 10.4 0.0 3.2 3 0 0 3 3 3 2 50S ribosome-binding GTPase Miro PF08477.8 XP_011271785.1 - 0.0015 18.9 0.5 0.78 10.2 0.0 3.1 2 0 0 2 2 2 1 Miro-like protein AAA_18 PF13238.1 XP_011271785.1 - 0.0022 18.2 11.0 0.33 11.2 0.1 4.1 3 1 0 3 3 3 2 AAA domain AAA_22 PF13401.1 XP_011271785.1 - 0.0024 17.9 5.2 1.3 9.2 0.1 3.7 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.1 XP_011271785.1 - 0.0059 16.9 1.9 0.0059 16.9 1.3 4.1 2 2 1 3 3 2 2 AAA domain Dynamin_N PF00350.18 XP_011271785.1 - 0.0059 16.4 0.9 1.2 8.9 0.3 2.9 2 0 0 2 2 2 1 Dynamin family AAA_10 PF12846.2 XP_011271785.1 - 0.0068 15.8 1.3 0.94 8.8 0.0 2.7 3 0 0 3 3 3 1 AAA-like domain AAA_25 PF13481.1 XP_011271785.1 - 0.0097 15.3 1.6 0.31 10.4 0.0 2.7 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.7 XP_011271785.1 - 0.024 13.7 2.1 3.1 6.8 0.0 3.0 3 0 0 3 3 3 0 Zeta toxin AAA_30 PF13604.1 XP_011271785.1 - 0.039 13.5 0.7 6.2 6.3 0.0 2.7 3 0 0 3 3 3 0 AAA domain ATP_bind_1 PF03029.12 XP_011271785.1 - 0.048 13.1 2.3 1.6 8.2 0.2 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein IstB_IS21 PF01695.12 XP_011271785.1 - 0.072 12.4 1.6 2.7 7.3 0.0 2.9 3 0 0 3 3 3 0 IstB-like ATP binding protein ATP-synt_ab PF00006.20 XP_011271785.1 - 0.095 12.1 0.2 10 5.5 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 XP_011271785.1 - 0.24 10.8 0.4 8.4 5.8 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Vps51 PF08700.6 XP_011271785.1 - 0.35 10.7 4.3 0.093 12.5 0.1 2.2 2 0 0 2 2 2 0 Vps51/Vps67 Nfu_N PF08712.6 XP_011271786.1 - 9.7e-31 105.2 0.1 2e-30 104.2 0.0 1.6 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 XP_011271786.1 - 1.4e-20 72.8 0.0 2.2e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 NifU-like domain CENP-R PF06729.7 XP_011271786.1 - 0.12 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Kinetochore component, CENP-R RRM_1 PF00076.17 XP_011271787.1 - 7.6e-56 185.6 0.2 1.3e-20 72.7 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 XP_011271787.1 - 1.8e-39 133.5 0.0 2e-15 56.5 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 XP_011271787.1 - 2.4e-26 91.3 0.0 5.9e-10 38.8 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSD PF00313.17 XP_011271787.1 - 0.053 13.2 5.3 0.61 9.9 0.1 3.6 3 1 1 4 4 4 0 'Cold-shock' DNA-binding domain Limkain-b1 PF11608.3 XP_011271787.1 - 0.056 13.1 0.4 4.6 7.0 0.0 3.2 4 0 0 4 4 4 0 Limkain b1 HATPase_c PF02518.21 XP_011271787.1 - 0.064 12.9 0.0 0.24 11.1 0.0 1.9 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Linker_histone PF00538.14 XP_011271788.1 - 2.1e-24 85.4 0.0 4e-24 84.4 0.0 1.5 1 0 0 1 1 1 1 linker histone H1 and H5 family TRF PF08558.5 XP_011271789.1 - 6.1e-73 245.0 1.0 1.6e-72 243.7 0.7 1.7 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.26 XP_011271789.1 - 2.3e-08 33.9 0.3 4.9e-08 32.9 0.2 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 XP_011271789.1 - 6.3e-05 22.9 0.0 0.00031 20.7 0.0 2.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain WD40 PF00400.27 XP_011271790.1 - 1.2e-40 135.9 21.4 3.6e-07 29.7 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 XP_011271790.1 - 0.09 11.0 0.2 1.1 7.4 0.0 2.6 3 0 0 3 3 3 0 Cytochrome D1 heme domain YEATS PF03366.11 XP_011271791.1 - 4.6e-23 80.7 0.0 7.4e-23 80.0 0.0 1.4 1 0 0 1 1 1 1 YEATS family FlgM PF04316.8 XP_011271791.1 - 0.015 15.2 0.0 0.62 10.0 0.0 2.4 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM DUF1397 PF07165.6 XP_011271791.1 - 0.073 12.2 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1397) RRM_1 PF00076.17 XP_011271793.1 - 2.2e-10 40.0 0.0 4.6e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 XP_011271793.1 - 1.3e-09 37.8 0.0 2.8e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 XP_011271793.1 - 0.00014 21.6 0.0 0.00026 20.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.1 XP_011271794.1 - 1.6e-06 27.6 11.7 2.7e-06 26.9 8.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Aminotran_1_2 PF00155.16 XP_011271795.1 - 2.1e-75 253.9 0.0 2.4e-75 253.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cytokin_check_N PF10407.4 XP_011271796.1 - 5.1e-26 90.0 0.3 1.4e-25 88.7 0.2 1.8 1 0 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus SMC_N PF02463.14 XP_011271797.1 - 1.2e-51 175.0 61.8 1.6e-50 171.4 42.8 3.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 XP_011271797.1 - 3.1e-30 104.5 0.1 1.8e-29 102.1 0.0 2.4 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 XP_011271797.1 - 1.4e-14 54.9 26.0 1.4e-14 54.9 18.0 7.3 2 2 4 6 6 6 1 AAA domain AAA_21 PF13304.1 XP_011271797.1 - 2.3e-09 37.6 30.5 5e-07 29.9 10.3 5.3 2 2 2 4 4 4 2 AAA domain Reo_sigmaC PF04582.7 XP_011271797.1 - 5.8e-07 28.9 43.3 0.0016 17.6 1.4 5.6 3 2 1 5 5 5 5 Reovirus sigma C capsid protein AAA_29 PF13555.1 XP_011271797.1 - 0.00099 18.5 0.0 0.0025 17.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 XP_011271797.1 - 0.014 15.7 0.1 0.014 15.7 0.1 7.0 3 2 1 4 4 4 0 ABC transporter FtsK_SpoIIIE PF01580.13 XP_011271797.1 - 0.085 12.3 1.2 0.27 10.6 0.0 2.6 3 0 0 3 3 3 0 FtsK/SpoIIIE family DUF3708 PF12501.3 XP_011271797.1 - 1.4 8.7 3.6 2.8 7.7 0.2 3.2 2 0 0 2 2 2 0 Phosphate ATP-binding cassette transporter adh_short_C2 PF13561.1 XP_011271798.1 - 1.4e-19 70.8 0.0 1.1e-18 67.8 0.0 2.5 3 0 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase ketoacyl-synt PF00109.21 XP_011271798.1 - 1.9e-19 70.1 0.0 3.7e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.15 XP_011271798.1 - 5.2e-17 61.7 0.0 1.1e-16 60.6 0.0 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.17 XP_011271798.1 - 1.5e-14 53.8 0.8 3e-14 52.8 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 XP_011271798.1 - 5.7e-06 26.3 0.0 1.5e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 XP_011271798.1 - 0.0007 19.3 0.0 0.002 17.7 0.0 1.8 1 0 0 1 1 1 1 KR domain DZR PF12773.2 XP_011271799.1 - 0.0074 16.0 32.1 30 4.5 10.1 3.9 1 1 1 2 2 2 1 Double zinc ribbon Usp PF00582.21 XP_011271799.1 - 0.094 12.9 0.3 0.26 11.4 0.2 1.8 1 0 0 1 1 1 0 Universal stress protein family CFEM PF05730.6 XP_011271800.1 - 0.35 10.7 3.7 0.64 9.8 2.5 1.3 1 0 0 1 1 1 0 CFEM domain PBP PF01161.15 XP_011271801.1 - 3.6e-12 46.3 0.1 4.2e-12 46.1 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Pkinase PF00069.20 XP_011271802.1 - 3.2e-69 232.9 0.0 4.2e-69 232.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011271802.1 - 4.5e-37 127.5 0.0 6.3e-37 127.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Vpu PF00558.14 XP_011271802.1 - 0.025 14.1 1.5 0.11 12.0 1.1 2.0 1 1 0 1 1 1 0 Vpu protein Choline_kinase PF01633.15 XP_011271802.1 - 0.031 13.8 0.7 0.39 10.2 0.0 2.2 2 0 0 2 2 2 0 Choline/ethanolamine kinase APH PF01636.18 XP_011271802.1 - 0.067 12.9 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 XP_011271802.1 - 0.096 12.0 0.0 0.25 10.6 0.0 1.7 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL NAD_binding_6 PF08030.7 XP_011271803.1 - 2.5e-13 50.2 0.0 4.4e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 XP_011271803.1 - 1.4e-09 38.0 15.7 1.4e-09 38.0 10.9 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 XP_011271803.1 - 3.2e-08 33.3 0.1 7.5e-08 32.1 0.1 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 XP_011271803.1 - 0.0037 17.8 0.0 0.0096 16.4 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Ada_Zn_binding PF02805.11 XP_011271804.1 - 5.4e-05 22.6 2.0 0.00011 21.7 1.4 1.5 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.18 XP_011271804.1 - 0.00019 21.1 0.0 0.00049 19.8 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.2 XP_011271804.1 - 0.0082 16.2 0.0 0.017 15.2 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Glycogen_syn PF05693.8 XP_011271805.1 - 0 1106.3 0.0 0 1106.1 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 XP_011271805.1 - 3.5e-08 33.0 0.0 4.2e-05 23.0 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 XP_011271805.1 - 5.2e-06 26.6 0.1 9.2e-06 25.8 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Sec23_helical PF04815.10 XP_011271805.1 - 0.029 13.8 0.1 0.088 12.2 0.0 1.8 2 0 0 2 2 2 0 Sec23/Sec24 helical domain LSM PF01423.17 XP_011271806.1 - 1.9e-09 36.9 0.3 2.5e-09 36.5 0.2 1.2 1 0 0 1 1 1 1 LSM domain SLEI_Leptospira PF07620.6 XP_011271806.1 - 0.13 12.1 0.5 0.45 10.4 0.4 2.0 1 0 0 1 1 1 0 SLEI BPL_N PF09825.4 XP_011271807.1 - 0.51 9.0 9.9 0.63 8.7 6.9 1.1 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal DUF3186 PF11382.3 XP_011271807.1 - 0.64 9.0 5.3 1 8.4 3.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) DUF605 PF04652.11 XP_011271807.1 - 1 8.7 22.2 1.2 8.4 15.4 1.1 1 0 0 1 1 1 0 Vta1 like DUF4407 PF14362.1 XP_011271807.1 - 1 8.2 4.7 1.2 8.0 3.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Trypan_PARP PF05887.6 XP_011271807.1 - 1.2 8.9 10.3 1.9 8.2 7.1 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) GAGA_bind PF06217.7 XP_011271807.1 - 1.7 8.5 14.6 2 8.2 10.1 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family LMBR1 PF04791.11 XP_011271807.1 - 3.5 6.0 5.1 4 5.9 3.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein UQ_con PF00179.21 XP_011271808.1 - 1.3e-28 99.1 0.1 1.7e-28 98.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Ribonuclease_3 PF00636.21 XP_011271810.1 - 3.3e-08 33.9 0.1 1.4e-07 31.9 0.0 2.0 2 0 0 2 2 2 1 Ribonuclease III domain dsrm PF00035.20 XP_011271810.1 - 4.8e-07 30.2 0.0 1.2e-06 29.0 0.0 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.1 XP_011271810.1 - 0.0016 18.3 0.4 0.32 10.9 0.0 3.1 2 1 1 3 3 3 1 Ribonuclease-III-like Peptidase_C27 PF05407.7 XP_011271810.1 - 0.035 13.8 0.0 0.17 11.5 0.0 2.0 3 0 0 3 3 3 0 Rubella virus endopeptidase HMG_box PF00505.14 XP_011271811.1 - 4.2e-06 26.9 0.4 0.024 14.9 0.0 2.7 2 0 0 2 2 2 2 HMG (high mobility group) box FTHFS PF01268.14 XP_011271812.1 - 2.3e-250 831.3 2.6 2.9e-250 831.0 1.8 1.1 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 XP_011271812.1 - 3.3e-69 231.0 1.5 6.9e-69 230.0 0.2 2.0 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 XP_011271812.1 - 2.8e-31 107.9 0.8 2.8e-31 107.9 0.5 2.5 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Saccharop_dh_N PF04455.7 XP_011271812.1 - 0.052 13.6 0.1 0.89 9.7 0.0 2.6 2 0 0 2 2 2 0 LOR/SDH bifunctional enzyme conserved region IF2_N PF04760.10 XP_011271812.1 - 0.2 11.3 3.0 9.7 5.9 0.0 3.7 5 0 0 5 5 5 0 Translation initiation factor IF-2, N-terminal region Complex1_LYR PF05347.10 XP_011271813.1 - 2.4e-08 33.6 1.2 5.5e-08 32.4 0.8 1.6 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 XP_011271813.1 - 6e-07 29.5 0.7 6e-07 29.5 0.5 2.0 2 1 0 2 2 2 1 Complex1_LYR-like SKN1 PF03935.10 XP_011271814.1 - 5e-209 694.6 2.1 7.4e-209 694.0 1.4 1.2 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Phytoreo_P8 PF07124.6 XP_011271814.1 - 0.039 12.6 0.0 0.065 11.8 0.0 1.2 1 0 0 1 1 1 0 Phytoreovirus outer capsid protein P8 LRR19-TM PF15176.1 XP_011271814.1 - 0.083 12.5 1.2 2.9 7.6 0.0 3.1 2 1 0 2 2 2 0 Leucine-rich repeat family 19 TM domain TFIIE_alpha PF02002.12 XP_011271815.1 - 2.1e-21 75.4 0.0 5.4e-21 74.0 0.0 1.7 1 0 0 1 1 1 1 TFIIE alpha subunit TF_Zn_Ribbon PF08271.7 XP_011271815.1 - 2.1e-08 33.3 0.4 6.5e-08 31.7 0.3 1.9 1 0 0 1 1 1 1 TFIIB zinc-binding Nop14 PF04147.7 XP_011271815.1 - 0.013 13.4 31.9 0.022 12.7 22.1 1.3 1 0 0 1 1 1 0 Nop14-like family zf-Di19 PF05605.7 XP_011271815.1 - 0.074 13.1 2.3 1.4 9.1 0.0 3.0 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding HTH_Crp_2 PF13545.1 XP_011271815.1 - 0.12 12.1 0.0 0.37 10.6 0.0 1.8 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Mucin PF01456.12 XP_011271815.1 - 2 8.1 6.3 5 6.9 4.4 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Myc_N PF01056.13 XP_011271815.1 - 8.4 5.4 19.3 5 6.2 12.0 1.6 1 1 1 2 2 2 0 Myc amino-terminal region PhyH PF05721.8 XP_011271816.1 - 2e-47 161.9 0.0 2.6e-47 161.6 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.1 XP_011271816.1 - 0.04 14.1 0.0 0.093 13.0 0.0 1.7 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase AATase PF07247.7 XP_011271817.1 - 2.4e-73 247.3 15.1 2.8e-73 247.0 10.5 1.0 1 0 0 1 1 1 1 Alcohol acetyltransferase Ribosomal_L30 PF00327.15 XP_011271819.1 - 8.7e-07 28.4 0.1 1.2e-06 28.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ku PF02735.11 XP_011271820.1 - 3.9e-25 88.4 0.1 3.9e-25 88.4 0.1 1.8 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 XP_011271820.1 - 3.6e-15 55.9 3.8 1e-14 54.5 2.6 1.8 1 1 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.9 XP_011271820.1 - 1.2e-08 35.3 0.8 6e-08 33.1 0.5 2.2 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm PadR PF03551.9 XP_011271820.1 - 0.004 16.9 0.2 0.27 11.0 0.0 2.7 2 0 0 2 2 2 1 Transcriptional regulator PadR-like family NUC153 PF08159.7 XP_011271821.1 - 2.2e-13 49.4 2.4 5.4e-13 48.2 1.7 1.7 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.27 XP_011271821.1 - 0.09 12.7 0.0 0.82 9.6 0.0 2.5 2 0 0 2 2 2 0 WD domain, G-beta repeat DUF2161 PF09929.4 XP_011271821.1 - 0.9 9.4 7.6 0.58 10.0 0.9 2.9 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2161) tRNA-synt_2b PF00587.20 XP_011271823.1 - 3.8e-36 124.2 0.1 7.6e-36 123.2 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 XP_011271823.1 - 2e-22 79.2 8.2 2e-22 79.2 5.7 2.0 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain WD40 PF00400.27 XP_011271826.1 - 1.8e-31 106.8 16.6 3.4e-10 39.3 0.1 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 XP_011271826.1 - 2.2e-05 23.4 1.0 0.3 9.7 0.0 3.2 1 1 2 3 3 3 3 Nup133 N terminal like BBS2_Mid PF14783.1 XP_011271826.1 - 0.00057 19.6 0.1 2.4 7.9 0.0 4.7 4 2 1 5 5 5 1 Ciliary BBSome complex subunit 2, middle region SWIRM PF04433.12 XP_011271827.1 - 5.8e-14 51.9 0.0 1.1e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 SWIRM domain CPSase_L_D2 PF02786.12 XP_011271829.1 - 4.9e-83 277.5 0.3 8.3e-83 276.8 0.2 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 XP_011271829.1 - 3.8e-65 218.9 0.0 7e-65 218.1 0.0 1.5 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 XP_011271829.1 - 3.1e-35 120.5 0.1 6.9e-35 119.4 0.1 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 XP_011271829.1 - 4.5e-30 103.7 0.0 2.2e-29 101.5 0.0 2.1 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 XP_011271829.1 - 3.8e-29 102.0 0.1 8.4e-29 100.8 0.0 1.6 1 0 0 1 1 1 1 HMGL-like ATPgrasp_Ter PF15632.1 XP_011271829.1 - 1.2e-19 70.2 0.1 1.5e-18 66.6 0.0 2.3 2 1 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl PF00364.17 XP_011271829.1 - 7.6e-19 67.1 4.8 7.6e-19 67.1 3.4 3.1 3 0 0 3 3 3 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 XP_011271829.1 - 5.7e-17 62.0 0.1 1.1e-16 61.1 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 XP_011271829.1 - 4.2e-09 35.9 3.0 0.0011 18.5 0.2 2.8 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 XP_011271829.1 - 5.9e-07 29.0 0.0 1.2e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 XP_011271829.1 - 2.8e-06 26.7 0.0 6.8e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 XP_011271829.1 - 1.8e-05 24.2 0.0 4.5e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 XP_011271829.1 - 0.00042 20.2 0.0 0.0018 18.1 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain HlyD_2 PF12700.2 XP_011271829.1 - 0.00062 19.0 0.7 0.33 10.0 0.0 2.3 1 1 1 2 2 2 2 HlyD family secretion protein HlyD PF00529.15 XP_011271829.1 - 0.00071 18.9 1.5 0.67 9.2 0.1 2.4 2 0 0 2 2 2 2 HlyD family secretion protein HlyD_3 PF13437.1 XP_011271829.1 - 0.012 15.9 0.4 0.19 12.0 0.2 2.8 1 1 1 2 2 2 0 HlyD family secretion protein Serine_rich PF08824.5 XP_011271829.1 - 0.072 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Serine rich protein interaction domain Death PF00531.17 XP_011271829.1 - 0.22 11.3 0.0 0.53 10.0 0.0 1.6 1 0 0 1 1 1 0 Death domain GCV_H PF01597.14 XP_011271829.1 - 0.85 9.3 3.5 0.84 9.3 0.4 2.5 3 0 0 3 3 2 0 Glycine cleavage H-protein MFS_1 PF07690.11 XP_011271830.1 - 2.6e-15 56.0 16.5 2.6e-15 56.0 11.4 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily AA_permease PF00324.16 XP_011271831.1 - 1.5e-122 409.3 49.3 1.7e-122 409.1 34.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 XP_011271831.1 - 1.3e-35 122.8 52.4 1.5e-35 122.5 36.3 1.0 1 0 0 1 1 1 1 Amino acid permease CagY_I PF14585.1 XP_011271831.1 - 0.035 14.0 2.8 0.063 13.2 1.9 1.3 1 0 0 1 1 1 0 CagY type 1 repeat gpUL132 PF11359.3 XP_011271831.1 - 8.2 5.6 6.0 1 8.6 0.1 2.4 3 0 0 3 3 3 0 Glycoprotein UL132 E1-E2_ATPase PF00122.15 XP_011271834.1 - 1.1e-48 165.3 0.5 2.3e-48 164.2 0.4 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 XP_011271834.1 - 3.4e-40 138.7 0.8 9.6e-40 137.2 0.0 2.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 XP_011271834.1 - 1.8e-32 111.2 10.1 2.9e-11 43.3 0.7 4.5 4 0 0 4 4 4 3 Heavy-metal-associated domain HAD PF12710.2 XP_011271834.1 - 1e-11 45.3 0.0 3.8e-11 43.5 0.0 2.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 XP_011271834.1 - 9e-09 35.2 0.4 0.00013 21.6 0.1 3.0 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase YscJ_FliF PF01514.12 XP_011271834.1 - 0.0017 17.5 0.5 0.7 9.0 0.1 2.6 2 0 0 2 2 2 2 Secretory protein of YscJ/FliF family DUF3133 PF11331.3 XP_011271834.1 - 0.035 13.6 4.8 10 5.8 0.2 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3133) Fer2_2 PF01799.15 XP_011271834.1 - 0.15 11.9 0.7 12 5.8 0.0 3.3 3 0 0 3 3 3 0 [2Fe-2S] binding domain Tail_P2_I PF09684.5 XP_011271834.1 - 0.17 11.4 0.1 40 3.7 0.0 3.1 3 0 0 3 3 3 0 Phage tail protein (Tail_P2_I) WD40 PF00400.27 XP_011271835.1 - 6.9e-12 44.7 10.7 0.0007 19.3 0.0 7.8 8 0 0 8 8 8 5 WD domain, G-beta repeat NDUFA12 PF05071.11 XP_011271836.1 - 5.2e-09 36.5 2.2 5.2e-09 36.5 1.5 1.8 2 0 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 PX PF00787.19 XP_011271837.1 - 6.1e-20 71.1 0.0 1.8e-19 69.6 0.0 1.7 2 0 0 2 2 2 1 PX domain Hint PF01079.15 XP_011271837.1 - 0.0036 16.5 0.4 0.0051 16.0 0.3 1.1 1 0 0 1 1 1 1 Hint module AMP-binding PF00501.23 XP_011271838.1 - 7.1e-60 202.5 0.0 8.9e-60 202.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 XP_011271838.1 - 3.5e-05 24.6 0.0 9.7e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Acyltransferase PF01553.16 XP_011271839.1 - 5.2e-27 93.8 0.0 8.1e-27 93.2 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Asparaginase PF00710.15 XP_011271840.1 - 1.6e-70 237.4 0.0 1.9e-70 237.2 0.0 1.0 1 0 0 1 1 1 1 Asparaginase MFS_1 PF07690.11 XP_011271841.1 - 6.6e-45 153.3 10.2 1.8e-44 151.9 7.1 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Collagen PF01391.13 XP_011271842.1 - 7.7e-07 28.5 22.4 7.7e-07 28.5 15.5 2.6 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) PNK3P PF08645.6 XP_011271842.1 - 0.053 12.9 0.6 0.092 12.1 0.4 1.3 1 0 0 1 1 1 0 Polynucleotide kinase 3 phosphatase Fig1 PF12351.3 XP_011271843.1 - 3.5e-51 173.6 3.4 4.6e-51 173.3 2.3 1.1 1 0 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.7 XP_011271843.1 - 1.7e-06 27.7 4.7 2.5e-06 27.2 3.2 1.2 1 0 0 1 1 1 1 SUR7/PalI family DUF3753 PF12575.3 XP_011271843.1 - 0.76 9.6 4.0 0.77 9.5 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) Abhydrolase_5 PF12695.2 XP_011271844.1 - 1.6e-08 34.3 0.0 2.6e-08 33.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 XP_011271844.1 - 5.2e-07 29.1 0.0 2.5e-06 26.9 0.0 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.15 XP_011271844.1 - 0.00025 20.6 0.0 0.00055 19.5 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 XP_011271844.1 - 0.0074 16.1 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PAF-AH_p_II PF03403.8 XP_011271844.1 - 0.013 13.8 0.0 0.018 13.3 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Ser_hydrolase PF06821.8 XP_011271844.1 - 0.024 14.2 0.0 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase Abhydrolase_2 PF02230.11 XP_011271844.1 - 0.033 13.6 0.0 0.048 13.0 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase VirJ PF06057.6 XP_011271844.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) ATP-synt PF00231.14 XP_011271845.1 - 5.3e-73 245.8 6.9 6.1e-73 245.6 4.8 1.0 1 0 0 1 1 1 1 ATP synthase FAD_binding_5 PF00941.16 XP_011271845.1 - 0.15 11.5 1.5 0.61 9.5 1.0 1.9 1 1 0 1 1 1 0 FAD binding domain in molybdopterin dehydrogenase GCV_T PF01571.16 XP_011271846.1 - 1.6e-61 207.3 0.0 2.1e-61 206.9 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 XP_011271846.1 - 5.6e-16 58.3 0.0 9e-16 57.6 0.0 1.3 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.7 XP_011271846.1 - 0.078 12.8 0.0 0.26 11.1 0.0 1.8 2 0 0 2 2 2 0 Sarcosine oxidase, gamma subunit family AA_permease PF00324.16 XP_011271847.1 - 4.4e-89 299.0 40.3 5.4e-89 298.7 28.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 XP_011271847.1 - 1.4e-27 96.3 44.7 1.7e-27 96.0 31.0 1.1 1 0 0 1 1 1 1 Amino acid permease Atg31 PF09795.4 XP_011271848.1 - 0.03 14.0 11.0 0.16 11.6 7.6 2.0 1 1 0 1 1 1 0 Autophagy-related protein 31 DEAD PF00270.24 XP_011271849.1 - 7.7e-44 149.1 1.1 1.8e-43 147.9 0.4 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 XP_011271849.1 - 8.1e-28 96.1 0.2 2.4e-27 94.5 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 XP_011271849.1 - 0.00077 19.1 0.3 0.0021 17.7 0.0 1.9 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 XP_011271849.1 - 0.00097 18.7 0.1 0.0057 16.2 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 XP_011271849.1 - 0.0047 17.0 0.5 0.02 15.0 0.4 2.0 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 XP_011271849.1 - 0.0052 16.6 0.0 0.015 15.1 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 XP_011271849.1 - 0.027 13.2 0.0 0.048 12.4 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain AAA_11 PF13086.1 XP_011271849.1 - 0.029 13.9 0.4 0.08 12.5 0.3 2.0 1 1 0 1 1 1 0 AAA domain Helicase_RecD PF05127.9 XP_011271849.1 - 0.037 13.6 0.0 0.062 12.9 0.0 1.4 1 0 0 1 1 1 0 Helicase Flavi_DEAD PF07652.9 XP_011271849.1 - 0.04 13.6 0.1 0.17 11.6 0.1 2.1 1 1 0 1 1 1 0 Flavivirus DEAD domain PRK PF00485.13 XP_011271850.1 - 1.3e-14 54.1 0.0 2.3e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 XP_011271850.1 - 0.0029 17.9 1.2 0.0048 17.2 0.8 1.4 1 1 0 1 1 1 1 AAA domain FRG1 PF06229.7 XP_011271851.1 - 7.7e-11 41.8 0.2 1.5e-10 40.8 0.1 1.4 1 0 0 1 1 1 1 FRG1-like family Fascin PF06268.8 XP_011271851.1 - 0.0055 16.7 0.0 0.013 15.5 0.0 1.6 1 1 0 1 1 1 1 Fascin domain Cpn60_TCP1 PF00118.19 XP_011271852.1 - 4.1e-98 329.1 4.5 5.1e-98 328.7 3.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Alpha-amylase_C PF02806.13 XP_011271853.1 - 3.2e-23 81.6 0.6 8e-23 80.3 0.1 2.0 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 XP_011271853.1 - 1.2e-18 67.6 0.1 2.1e-16 60.2 0.0 2.7 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.13 XP_011271853.1 - 3.8e-15 55.6 0.1 2.2e-14 53.2 0.1 2.2 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) hDGE_amylase PF14701.1 XP_011271853.1 - 0.033 13.1 0.0 0.055 12.3 0.0 1.2 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme DUF4560 PF15118.1 XP_011271853.1 - 0.13 12.0 0.1 0.39 10.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4560) ACBP PF00887.14 XP_011271854.1 - 3.1e-19 68.4 0.0 8.9e-19 66.9 0.0 1.8 1 1 0 1 1 1 1 Acyl CoA binding protein Ribosomal_L11_N PF03946.9 XP_011271855.1 - 8.5e-17 60.3 0.5 2.6e-16 58.8 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 XP_011271855.1 - 4.8e-11 42.6 0.8 8.9e-11 41.7 0.5 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Lon_C PF05362.8 XP_011271855.1 - 0.058 12.6 0.2 0.067 12.4 0.1 1.2 1 0 0 1 1 1 0 Lon protease (S16) C-terminal proteolytic domain Pab87_oct PF13969.1 XP_011271855.1 - 0.095 12.8 0.0 0.27 11.3 0.0 1.8 1 1 0 1 1 1 0 Pab87 octamerisation domain Mak10 PF04112.8 XP_011271856.1 - 2.7e-41 140.5 1.3 5.8e-41 139.5 0.2 2.1 2 0 0 2 2 2 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase NEMO PF11577.3 XP_011271856.1 - 1.5 8.6 12.1 0.12 12.1 2.2 3.1 3 0 0 3 3 3 0 NF-kappa-B essential modulator NEMO AFG1_ATPase PF03969.11 XP_011271857.1 - 1.9e-74 250.6 0.0 5.5e-71 239.2 0.0 2.2 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.1 XP_011271857.1 - 5.7e-06 26.4 1.1 0.059 13.3 0.0 3.0 3 1 1 4 4 4 2 AAA ATPase domain NACHT PF05729.7 XP_011271857.1 - 2.8e-05 23.8 0.1 0.003 17.2 0.1 3.0 2 1 0 2 2 2 1 NACHT domain AAA PF00004.24 XP_011271857.1 - 0.013 15.6 0.0 0.062 13.4 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 XP_011271857.1 - 0.021 14.5 0.0 0.049 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 XP_011271857.1 - 0.023 14.8 0.0 0.082 13.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 XP_011271857.1 - 0.023 14.5 0.0 0.078 12.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 XP_011271857.1 - 0.032 14.4 0.0 0.084 13.0 0.0 1.8 1 0 0 1 1 1 0 RNA helicase TPR_19 PF14559.1 XP_011271858.1 - 6.5e-08 32.8 0.0 1.1 9.6 0.0 5.6 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 XP_011271858.1 - 2.4e-07 30.7 0.0 4 8.3 0.0 6.6 4 2 3 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.1 XP_011271858.1 - 1.2e-06 28.3 0.1 0.079 12.9 0.0 5.1 5 1 0 5 5 5 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 XP_011271858.1 - 3e-06 27.0 10.2 0.26 11.0 0.1 6.4 5 3 2 7 7 7 2 Mad3/BUB1 homology region 1 TPR_15 PF13429.1 XP_011271858.1 - 7.9e-06 25.1 0.0 0.011 14.8 0.0 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 XP_011271858.1 - 0.00032 20.2 0.1 0.11 12.2 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 XP_011271858.1 - 0.00037 21.0 0.0 0.0019 18.8 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 XP_011271858.1 - 0.00063 19.4 0.2 11 6.2 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat NRDE-2 PF08424.5 XP_011271858.1 - 0.55 9.0 19.9 0.71 8.6 3.4 5.4 4 3 0 5 5 5 0 NRDE-2, necessary for RNA interference ATP-synt_D PF01813.12 XP_011271859.1 - 7.4e-61 205.1 2.3 7.4e-61 205.1 1.6 1.7 2 0 0 2 2 2 1 ATP synthase subunit D DUF2201_N PF13203.1 XP_011271859.1 - 0.021 14.0 6.4 0.029 13.5 4.4 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain DDHD PF02862.12 XP_011271859.1 - 0.23 11.2 8.7 0.5 10.1 6.0 1.5 1 0 0 1 1 1 0 DDHD domain DUF1510 PF07423.6 XP_011271859.1 - 0.31 10.3 16.9 0.44 9.8 11.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Hid1 PF12722.2 XP_011271859.1 - 0.79 7.3 7.1 0.97 7.0 4.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Daxx PF03344.10 XP_011271859.1 - 1.7 7.0 21.8 2.3 6.6 15.1 1.1 1 0 0 1 1 1 0 Daxx Family Spore_coat_CotO PF14153.1 XP_011271859.1 - 3 7.2 16.6 5.4 6.4 11.5 1.4 1 0 0 1 1 1 0 Spore coat protein CotO Sec62 PF03839.11 XP_011271859.1 - 4 6.7 13.8 5.9 6.2 9.6 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 CPSF100_C PF13299.1 XP_011271859.1 - 10 6.3 12.7 30 4.7 8.8 1.8 1 1 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Peptidase_M28 PF04389.12 XP_011271860.1 - 1.8e-29 102.7 0.1 3.2e-29 101.9 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 XP_011271860.1 - 7.4e-08 32.1 0.0 1e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 TPP1 PF10341.4 XP_011271861.1 - 1.1e-13 51.0 0.6 1.4e-13 50.7 0.4 1.3 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD Ribosomal_L2_C PF03947.13 XP_011271862.1 - 4.8e-46 155.7 4.0 4.8e-46 155.7 2.8 1.7 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 XP_011271862.1 - 5.2e-26 90.4 3.7 1.2e-25 89.2 1.5 2.2 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain eIF2_C PF09173.6 XP_011271862.1 - 0.079 13.0 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 Initiation factor eIF2 gamma, C terminal OSCP PF00213.13 XP_011271863.1 - 7.2e-43 146.4 2.7 8.3e-43 146.2 1.9 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit vATP-synt_E PF01991.13 XP_011271863.1 - 0.045 13.0 0.8 0.14 11.4 0.5 1.7 1 1 1 2 2 2 0 ATP synthase (E/31 kDa) subunit Methyltransf_32 PF13679.1 XP_011271864.1 - 4.6e-10 39.3 0.0 9.1e-10 38.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain FA_hydroxylase PF04116.8 XP_011271865.1 - 3e-18 66.2 3.5 3e-18 66.2 2.5 1.9 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Mhr1 PF12829.2 XP_011271866.1 - 3.4e-33 113.3 0.2 3.4e-33 113.3 0.2 2.0 2 1 0 2 2 2 1 Transcriptional regulation of mitochondrial recombination Viral_DNA_bp PF00747.12 XP_011271866.1 - 0.1 9.7 0.4 0.13 9.4 0.3 1.1 1 0 0 1 1 1 0 ssDNA binding protein zf-RING_2 PF13639.1 XP_011271867.1 - 1e-08 34.8 6.4 1.6e-08 34.1 4.5 1.4 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.3 XP_011271867.1 - 2.4e-06 27.4 5.2 5.5e-06 26.2 3.6 1.5 1 0 0 1 1 1 1 FANCL C-terminal domain zf-rbx1 PF12678.2 XP_011271867.1 - 4.2e-06 26.7 2.8 7.9e-06 25.9 1.9 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 XP_011271867.1 - 0.00026 20.7 2.7 0.00051 19.8 1.9 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 XP_011271867.1 - 0.0015 18.1 8.1 0.0026 17.3 5.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.17 XP_011271867.1 - 0.0045 16.6 3.4 0.0085 15.7 2.3 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) RINGv PF12906.2 XP_011271867.1 - 0.0058 16.6 7.0 0.0097 15.9 4.9 1.4 1 0 0 1 1 1 1 RING-variant domain zf-C3HC4_2 PF13923.1 XP_011271867.1 - 0.039 13.9 7.9 0.067 13.2 5.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Phage_min_cap2 PF06152.6 XP_011271867.1 - 0.22 10.4 3.0 0.28 10.0 0.3 2.3 2 0 0 2 2 2 0 Phage minor capsid protein 2 zf-C3HC4_3 PF13920.1 XP_011271867.1 - 0.39 10.4 4.6 0.76 9.5 3.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 XP_011271867.1 - 0.57 10.2 6.3 0.94 9.5 4.4 1.4 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.1 XP_011271867.1 - 0.68 9.5 5.7 6.6 6.4 3.8 2.2 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.24 XP_011271867.1 - 2.9 7.6 6.6 4.8 6.9 4.6 1.4 1 0 0 1 1 1 0 PHD-finger TRM13 PF05206.9 XP_011271868.1 - 1.9e-78 263.2 3.3 3.6e-78 262.3 2.3 1.4 1 0 0 1 1 1 1 Methyltransferase TRM13 zf-TRM13_CCCH PF11722.3 XP_011271868.1 - 4.6e-11 41.8 2.6 1.3e-10 40.4 1.8 1.9 1 0 0 1 1 1 1 CCCH zinc finger in TRM13 protein Methyltransf_32 PF13679.1 XP_011271868.1 - 1.6e-06 27.8 1.2 3.9e-06 26.5 0.8 1.6 1 0 0 1 1 1 1 Methyltransferase domain zf-U11-48K PF05253.7 XP_011271868.1 - 9.3e-06 25.2 1.8 2.4e-05 23.9 0.2 2.4 2 0 0 2 2 2 1 U11-48K-like CHHC zinc finger Methyltransf_31 PF13847.1 XP_011271868.1 - 0.00094 18.7 0.4 0.003 17.1 0.1 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 XP_011271868.1 - 0.026 15.0 0.0 0.078 13.4 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 XP_011271868.1 - 0.11 13.0 0.0 0.27 11.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain TCTP PF00838.12 XP_011271869.1 - 4.2e-67 225.2 2.8 5.5e-67 224.8 2.0 1.1 1 0 0 1 1 1 1 Translationally controlled tumour protein adh_short PF00106.20 XP_011271871.1 - 2.3e-30 105.6 0.0 2.8e-30 105.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 XP_011271871.1 - 5.1e-30 105.0 0.8 8.9e-30 104.2 0.6 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 XP_011271871.1 - 1.7e-12 47.3 0.0 2e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 XP_011271871.1 - 0.0014 18.1 0.1 0.0021 17.5 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 XP_011271871.1 - 0.027 13.6 0.7 0.037 13.1 0.5 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 XP_011271871.1 - 0.071 13.1 0.0 0.14 12.1 0.0 1.5 1 1 0 1 1 1 0 NADH(P)-binding BUD22 PF09073.5 XP_011271872.1 - 5.2e-76 256.4 62.0 6.6e-76 256.1 43.0 1.1 1 0 0 1 1 1 1 BUD22 Daxx PF03344.10 XP_011271872.1 - 0.45 8.9 43.1 0.68 8.3 29.9 1.3 1 0 0 1 1 1 0 Daxx Family PGM_PMM_I PF02878.11 XP_011271873.1 - 1.3e-34 118.6 0.1 2e-34 118.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 XP_011271873.1 - 3.9e-23 81.6 0.0 7.4e-23 80.7 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 XP_011271873.1 - 1.4e-12 47.8 0.0 6.2e-12 45.7 0.0 2.1 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 XP_011271873.1 - 6e-10 38.9 0.0 1.3e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Aminotran_1_2 PF00155.16 XP_011271874.1 - 6.1e-70 235.9 0.0 7.2e-70 235.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II AcylCoA_DH_N PF12418.3 XP_011271874.1 - 0.079 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase N terminal Peptidase_M41 PF01434.13 XP_011271875.1 - 4.1e-72 242.1 0.0 8.2e-72 241.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 XP_011271875.1 - 6.1e-42 142.9 0.4 1.8e-41 141.4 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 XP_011271875.1 - 2.1e-09 37.5 0.5 6e-09 36.0 0.3 1.8 1 0 0 1 1 1 1 FtsH Extracellular AAA_17 PF13207.1 XP_011271875.1 - 0.00015 22.5 0.1 0.001 19.8 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 XP_011271875.1 - 0.00024 20.8 0.4 0.017 14.8 0.1 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 XP_011271875.1 - 0.00063 18.5 0.1 0.0013 17.5 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 XP_011271875.1 - 0.0061 15.6 0.0 0.013 14.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 XP_011271875.1 - 0.0067 16.1 1.0 0.023 14.4 0.5 1.9 2 0 0 2 2 2 1 Part of AAA domain AAA_25 PF13481.1 XP_011271875.1 - 0.0072 15.7 0.7 0.041 13.2 0.2 2.4 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.1 XP_011271875.1 - 0.0073 16.4 0.9 0.15 12.2 0.2 3.0 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 XP_011271875.1 - 0.012 15.0 0.0 0.032 13.6 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.1 XP_011271875.1 - 0.015 15.2 1.0 0.49 10.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 XP_011271875.1 - 0.027 14.4 2.3 0.066 13.2 0.1 2.4 2 1 0 2 2 2 0 AAA ATPase domain ArsC PF03960.10 XP_011271875.1 - 0.035 14.1 1.3 0.085 12.9 0.1 2.3 2 0 0 2 2 2 0 ArsC family AAA_33 PF13671.1 XP_011271875.1 - 0.094 12.5 0.0 0.27 11.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF1510 PF07423.6 XP_011271875.1 - 0.44 9.8 12.0 1 8.6 8.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) PRP1_N PF06424.7 XP_011271875.1 - 4.5 7.5 14.2 1.8 8.8 7.2 2.3 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal CRC_subunit PF08624.5 XP_011271876.1 - 9.2e-54 181.1 0.3 1.6e-53 180.3 0.2 1.4 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Nop14 PF04147.7 XP_011271876.1 - 0.18 9.7 20.5 0.27 9.0 14.2 1.2 1 0 0 1 1 1 0 Nop14-like family HrcA_DNA-bdg PF03444.10 XP_011271877.1 - 0.11 11.9 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding Zn_clus PF00172.13 XP_011271878.1 - 0.00061 19.6 12.7 0.0011 18.8 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Adenyl_transf PF04439.7 XP_011271878.1 - 0.077 11.9 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Streptomycin adenylyltransferase ADH_N PF08240.7 XP_011271879.1 - 5.7e-25 87.1 0.3 9.5e-25 86.4 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 XP_011271879.1 - 6.1e-17 61.3 0.0 1.9e-16 59.7 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 XP_011271879.1 - 0.0011 18.5 0.6 0.0018 17.8 0.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated 2-Hacid_dh_C PF02826.14 XP_011271879.1 - 0.14 11.3 0.0 0.31 10.1 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Aldedh PF00171.17 XP_011271881.1 - 5.1e-126 420.7 0.2 5.9e-126 420.5 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GvpH PF05455.6 XP_011271881.1 - 0.11 12.1 0.0 0.24 10.9 0.0 1.5 2 0 0 2 2 2 0 GvpH BOP1NT PF08145.7 XP_011271882.1 - 1.4e-104 349.4 5.1 2.8e-104 348.4 3.5 1.5 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 XP_011271882.1 - 2.7e-30 103.1 8.2 1.5e-10 40.5 0.1 7.5 7 1 0 7 7 7 6 WD domain, G-beta repeat Daxx PF03344.10 XP_011271882.1 - 8.6 4.6 25.2 1.1 7.7 14.6 1.5 2 0 0 2 2 2 0 Daxx Family SAM_decarbox PF01536.11 XP_011271883.1 - 2.8e-106 354.9 2.2 3.2e-106 354.7 1.6 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase RRM_1 PF00076.17 XP_011271884.1 - 1.2e-29 101.7 4.3 1.9e-15 56.2 0.0 2.6 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 XP_011271884.1 - 4.4e-14 52.2 0.7 2.3e-06 27.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 XP_011271884.1 - 1e-13 50.8 1.9 2.2e-08 33.8 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Imm36 PF15597.1 XP_011271884.1 - 0.028 14.5 1.9 0.34 11.0 0.1 2.3 1 1 1 2 2 2 0 Immunity protein 36 Limkain-b1 PF11608.3 XP_011271884.1 - 0.035 13.8 0.4 0.42 10.3 0.0 2.1 2 0 0 2 2 2 0 Limkain b1 Sec23_trunk PF04811.10 XP_011271885.1 - 4.2e-44 150.7 0.0 2.3e-43 148.3 0.0 1.9 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 XP_011271885.1 - 2.8e-18 65.2 0.5 7.1e-18 63.9 0.3 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 XP_011271885.1 - 6.2e-18 65.1 0.1 1.5e-17 63.8 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 XP_011271885.1 - 4.2e-11 42.2 6.7 7.1e-11 41.4 4.6 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 XP_011271885.1 - 3.2e-09 36.3 0.0 7.3e-09 35.2 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat HDA2-3 PF11496.3 XP_011271886.1 - 2.9e-63 213.4 9.3 2.9e-63 213.4 6.4 2.1 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Pyridoxal_deC PF00282.14 XP_011271887.1 - 1.2e-21 76.6 0.0 1.6e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 XP_011271887.1 - 3.3e-11 42.5 0.0 8.4e-11 41.2 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 XP_011271887.1 - 1.6e-05 24.1 0.0 2.5e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 XP_011271887.1 - 0.1 11.6 0.0 0.24 10.5 0.0 1.4 1 1 0 1 1 1 0 Beta-eliminating lyase PQ-loop PF04193.9 XP_011271888.1 - 2.1e-34 116.8 7.9 1.8e-17 62.6 0.4 2.4 2 0 0 2 2 2 2 PQ loop repeat Zip PF02535.17 XP_011271888.1 - 0.0014 17.7 0.2 0.0023 17.0 0.1 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter MtN3_slv PF03083.11 XP_011271888.1 - 0.01 15.6 7.0 0.021 14.6 0.0 3.2 2 1 1 3 3 3 0 Sugar efflux transporter for intercellular exchange Dimer_Tnp_hAT PF05699.9 XP_011271889.1 - 0.047 13.3 2.6 0.22 11.1 1.8 2.2 1 0 0 1 1 1 0 hAT family C-terminal dimerisation region ACCA PF03255.9 XP_011271889.1 - 0.11 11.9 1.3 0.38 10.2 0.0 2.4 2 1 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit MMgT PF10270.4 XP_011271890.1 - 7.3e-20 71.3 0.1 1.2e-19 70.6 0.1 1.4 1 0 0 1 1 1 1 Membrane magnesium transporter DUF2413 PF10310.4 XP_011271890.1 - 2.9 6.5 15.5 3.6 6.3 10.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) ABC_tran PF00005.22 XP_011271891.1 - 6.4e-46 156.0 0.0 2.8e-23 82.7 0.0 4.2 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 XP_011271891.1 - 1.1e-17 64.9 0.0 0.0023 17.9 0.0 4.5 4 0 0 4 4 4 4 AAA domain SMC_N PF02463.14 XP_011271891.1 - 5e-15 55.3 0.0 1.5e-06 27.5 0.0 3.7 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 XP_011271891.1 - 3.4e-10 40.5 0.9 0.00037 20.8 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 XP_011271891.1 - 8.1e-10 38.0 0.0 0.0015 17.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 XP_011271891.1 - 1.4e-09 38.1 0.0 0.00012 22.1 0.0 4.2 4 1 0 4 4 3 2 AAA domain DUF258 PF03193.11 XP_011271891.1 - 6.1e-09 35.2 0.0 8.2e-05 21.8 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 XP_011271891.1 - 1.1e-08 35.9 0.0 0.00096 19.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 XP_011271891.1 - 1.9e-08 34.4 0.1 0.00073 19.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain HEAT_2 PF13646.1 XP_011271891.1 - 1.1e-07 32.0 2.0 0.0096 16.1 0.0 3.7 1 1 2 3 3 3 2 HEAT repeats MMR_HSR1 PF01926.18 XP_011271891.1 - 4.7e-07 29.7 0.0 0.0055 16.6 0.0 3.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_15 PF13175.1 XP_011271891.1 - 1e-06 28.0 0.0 0.5 9.3 0.1 4.5 3 1 0 4 4 4 1 AAA ATPase domain SbcCD_C PF13558.1 XP_011271891.1 - 1.2e-06 28.3 0.0 0.003 17.4 0.0 3.1 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 XP_011271891.1 - 6.6e-06 25.7 0.0 0.18 11.2 0.0 3.3 4 0 0 4 4 4 2 AAA-like domain AAA_33 PF13671.1 XP_011271891.1 - 7.5e-06 25.8 0.0 0.2 11.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 XP_011271891.1 - 8.3e-06 26.1 0.1 0.017 15.3 0.0 3.4 4 0 0 4 4 2 1 AAA domain ArgK PF03308.11 XP_011271891.1 - 1.2e-05 24.2 0.1 0.065 12.0 0.0 2.5 2 0 0 2 2 2 2 ArgK protein Dynamin_N PF00350.18 XP_011271891.1 - 1.3e-05 25.0 0.0 0.00093 19.0 0.0 2.8 2 0 0 2 2 2 1 Dynamin family Miro PF08477.8 XP_011271891.1 - 1.7e-05 25.2 0.0 0.12 12.8 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein RNA_helicase PF00910.17 XP_011271891.1 - 2.2e-05 24.5 0.0 0.22 11.7 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA PF00004.24 XP_011271891.1 - 5.2e-05 23.4 0.0 0.35 11.0 0.0 3.8 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 XP_011271891.1 - 5.5e-05 22.9 0.0 0.35 10.5 0.0 3.0 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B Adaptin_N PF01602.15 XP_011271891.1 - 6.5e-05 21.4 2.0 0.0056 15.0 0.1 2.4 1 1 1 2 2 2 1 Adaptin N terminal region CLASP_N PF12348.3 XP_011271891.1 - 0.00013 21.4 0.2 0.00042 19.7 0.1 1.9 2 0 0 2 2 2 1 CLASP N terminal Arch_ATPase PF01637.13 XP_011271891.1 - 0.00014 21.6 0.0 0.21 11.2 0.0 3.1 2 0 0 2 2 2 1 Archaeal ATPase MutS_V PF00488.16 XP_011271891.1 - 0.00039 19.9 0.0 0.25 10.6 0.0 2.3 2 0 0 2 2 2 1 MutS domain V PduV-EutP PF10662.4 XP_011271891.1 - 0.00044 19.7 0.0 0.2 11.1 0.0 3.1 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 XP_011271891.1 - 0.00047 20.1 1.5 0.53 10.2 0.0 4.0 4 1 0 4 4 4 1 AAA ATPase domain AAA_13 PF13166.1 XP_011271891.1 - 0.00048 18.7 3.4 2 6.7 0.0 4.1 4 1 0 4 4 3 1 AAA domain AAA_14 PF13173.1 XP_011271891.1 - 0.00051 19.9 0.0 2.1 8.2 0.0 3.2 3 0 0 3 3 3 2 AAA domain DUF87 PF01935.12 XP_011271891.1 - 0.0014 18.5 0.5 0.31 10.8 0.0 3.6 4 0 0 4 4 2 1 Domain of unknown function DUF87 NACHT PF05729.7 XP_011271891.1 - 0.0019 17.8 0.0 0.74 9.4 0.0 2.4 2 0 0 2 2 2 1 NACHT domain HEAT PF02985.17 XP_011271891.1 - 0.0021 17.9 2.2 0.62 10.3 0.0 4.7 5 0 0 5 5 4 1 HEAT repeat cobW PF02492.14 XP_011271891.1 - 0.0021 17.5 0.9 1 8.7 0.0 3.2 4 0 0 4 4 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.1 XP_011271891.1 - 0.0023 17.5 0.0 2.9 7.4 0.0 3.2 4 0 0 4 4 3 1 AAA domain HEAT_EZ PF13513.1 XP_011271891.1 - 0.0024 18.2 3.9 5.8 7.5 0.0 5.2 4 1 2 6 6 5 0 HEAT-like repeat Cnd1 PF12717.2 XP_011271891.1 - 0.0026 17.6 0.2 0.96 9.2 0.0 3.6 2 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 AAA_25 PF13481.1 XP_011271891.1 - 0.0033 16.8 0.0 1.9 7.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 XP_011271891.1 - 0.013 14.6 0.0 0.46 9.6 0.0 2.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ATP-synt_ab PF00006.20 XP_011271891.1 - 0.021 14.3 0.0 4 6.8 0.0 3.0 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain Zeta_toxin PF06414.7 XP_011271891.1 - 0.022 13.8 0.0 5.5 6.0 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin Septin PF00735.13 XP_011271891.1 - 0.045 12.7 0.0 1.5 7.7 0.0 2.4 2 0 0 2 2 2 0 Septin UME PF08064.8 XP_011271891.1 - 0.054 13.4 0.1 0.24 11.3 0.1 2.0 2 0 0 2 2 1 0 UME (NUC010) domain DUF2813 PF11398.3 XP_011271891.1 - 0.076 12.0 0.0 0.2 10.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) AAA_19 PF13245.1 XP_011271891.1 - 0.079 12.7 0.1 5.7 6.7 0.0 2.8 2 0 0 2 2 2 0 Part of AAA domain NTPase_1 PF03266.10 XP_011271891.1 - 0.082 12.6 0.2 12 5.5 0.0 2.6 2 0 0 2 2 2 0 NTPase IstB_IS21 PF01695.12 XP_011271891.1 - 0.085 12.2 0.0 11 5.4 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein ATP_bind_1 PF03029.12 XP_011271891.1 - 0.094 12.2 0.4 8.1 5.9 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.13 XP_011271891.1 - 0.094 12.1 0.1 3.5 7.0 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family ParcG PF10274.4 XP_011271891.1 - 0.1 12.4 0.2 9.2 6.1 0.0 2.9 2 1 1 3 3 3 0 Parkin co-regulated protein Zip PF02535.17 XP_011271892.1 - 8.6e-32 110.4 20.0 5.8e-21 74.8 0.7 2.2 2 0 0 2 2 2 2 ZIP Zinc transporter Aft1_HRR PF11787.3 XP_011271892.1 - 0.0045 18.0 2.8 0.018 16.0 1.9 2.0 1 0 0 1 1 1 1 Aft1 HRR domain MFS_1 PF07690.11 XP_011271895.1 - 1.4e-19 70.0 15.8 1.4e-19 70.0 11.0 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 XP_011271895.1 - 4.3e-06 25.5 2.2 4.3e-06 25.5 1.5 2.2 3 0 0 3 3 3 1 Sugar (and other) transporter DUF3311 PF11755.3 XP_011271895.1 - 0.32 10.5 5.9 0.18 11.3 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3311) SMC_N PF02463.14 XP_011271896.1 - 2e-68 229.9 42.6 2e-68 229.9 29.6 3.1 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 XP_011271896.1 - 9.2e-27 93.4 0.0 5.2e-26 90.9 0.0 2.4 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 XP_011271896.1 - 1.7e-13 51.1 13.3 4e-09 36.8 2.1 5.4 2 2 3 5 5 5 2 AAA domain ATG16 PF08614.6 XP_011271896.1 - 7.7e-05 22.5 17.2 7.7e-05 22.5 11.9 8.8 4 2 7 11 11 11 2 Autophagy protein 16 (ATG16) AAA_29 PF13555.1 XP_011271896.1 - 0.00019 20.8 0.0 0.00042 19.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Tropomyosin_1 PF12718.2 XP_011271896.1 - 0.00051 19.9 25.5 0.00051 19.9 17.7 8.5 3 2 4 7 7 7 2 Tropomyosin like Laminin_I PF06008.9 XP_011271896.1 - 0.003 16.9 7.3 0.003 16.9 5.0 7.8 2 2 5 7 7 7 3 Laminin Domain I Reo_sigmaC PF04582.7 XP_011271896.1 - 0.11 11.6 39.3 0.62 9.1 1.6 5.5 2 2 3 6 6 6 0 Reovirus sigma C capsid protein Tropomyosin PF00261.15 XP_011271896.1 - 0.11 11.5 119.1 0.03 13.4 1.8 6.9 3 2 3 6 6 6 0 Tropomyosin IncA PF04156.9 XP_011271896.1 - 8.7 5.8 118.8 0.038 13.6 15.4 7.0 2 2 5 7 7 7 0 IncA protein Actin PF00022.14 XP_011271897.1 - 2.6e-59 200.6 0.0 3.2e-59 200.3 0.0 1.1 1 0 0 1 1 1 1 Actin SPX PF03105.14 XP_011271899.1 - 2.8e-08 33.8 2.4 2.8e-08 33.8 1.6 3.6 2 2 1 3 3 3 2 SPX domain Slu7 PF11708.3 XP_011271900.1 - 2.4e-51 174.7 22.5 3.6e-51 174.2 15.6 1.3 1 0 0 1 1 1 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.1 XP_011271900.1 - 0.11 12.1 1.7 0.33 10.6 0.6 2.2 2 0 0 2 2 2 0 Zinc knuckle Nop52 PF05997.7 XP_011271901.1 - 1.5e-46 158.5 1.3 1.5e-46 158.5 0.9 1.5 2 0 0 2 2 2 1 Nucleolar protein,Nop52 Nucleoplasmin PF03066.10 XP_011271901.1 - 0.15 11.5 18.8 0.82 9.1 1.1 2.2 2 0 0 2 2 2 0 Nucleoplasmin Kin17_mid PF10357.4 XP_011271901.1 - 0.49 10.0 4.9 6.2 6.4 1.5 2.3 2 0 0 2 2 2 0 Domain of Kin17 curved DNA-binding protein DUF1754 PF08555.5 XP_011271901.1 - 2.5 8.7 11.4 1.1 9.8 3.2 2.2 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) FAM176 PF14851.1 XP_011271901.1 - 4.1 7.0 14.2 3 7.5 0.4 2.2 2 0 0 2 2 2 0 FAM176 family NUT_C PF12882.2 XP_011271901.1 - 7.2 6.2 7.1 1.5 8.4 0.1 2.1 2 0 0 2 2 2 0 NUT protein C terminal CENP-B_dimeris PF09026.5 XP_011271901.1 - 8.5 6.6 22.5 5.2 7.3 1.3 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain RRM_6 PF14259.1 XP_011271902.1 - 0.0021 18.0 0.0 1.7 8.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Daxx PF03344.10 XP_011271902.1 - 0.049 12.1 22.6 0.073 11.5 15.7 1.1 1 0 0 1 1 1 0 Daxx Family RRM_1 PF00076.17 XP_011271902.1 - 0.056 13.0 0.0 3.1 7.4 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDC45 PF02724.9 XP_011271902.1 - 0.73 7.8 19.6 1.1 7.2 13.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 XP_011271902.1 - 9.4 4.0 29.4 13 3.5 20.4 1.1 1 0 0 1 1 1 0 Nop14-like family SecE PF00584.15 XP_011271903.1 - 4.1e-14 51.8 0.1 4.5e-14 51.7 0.1 1.0 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex SPT2 PF08243.6 XP_011271904.1 - 4.4e-23 81.7 28.6 4.4e-23 81.7 19.8 2.1 2 0 0 2 2 2 1 SPT2 chromatin protein Rad4 PF03835.10 XP_011271905.1 - 9.3e-29 99.6 2.5 4.8e-28 97.3 1.8 2.3 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 XP_011271905.1 - 4.3e-25 87.2 0.2 9.3e-25 86.1 0.1 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 XP_011271905.1 - 7.3e-21 73.4 0.1 1.8e-20 72.2 0.0 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 XP_011271905.1 - 4e-08 33.4 0.2 2.4e-07 30.9 0.1 2.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 XP_011271905.1 - 3.2e-05 24.1 0.0 9.4e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 Transglutaminase-like superfamily RED_N PF07808.8 XP_011271906.1 - 0.014 14.5 2.1 0.03 13.5 1.5 1.6 1 0 0 1 1 1 0 RED-like protein N-terminal region PQ-loop PF04193.9 XP_011271907.1 - 0.0063 16.0 1.3 0.0063 16.0 0.9 2.2 1 1 1 2 2 2 1 PQ loop repeat DUF1275 PF06912.6 XP_011271907.1 - 0.0068 15.6 0.1 0.011 14.9 0.1 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1275) ABC2_membrane_5 PF13346.1 XP_011271907.1 - 1.4 8.1 10.7 1.8 7.7 7.4 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Ion_trans_N PF08412.5 XP_011271908.1 - 0.094 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Ion transport protein N-terminal ChaC PF04752.7 XP_011271909.1 - 2.7e-53 180.5 0.0 3.5e-53 180.2 0.0 1.1 1 0 0 1 1 1 1 ChaC-like protein ABC_tran PF00005.22 XP_011271910.1 - 3.1e-34 118.2 0.0 4.7e-17 62.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter RLI PF04068.10 XP_011271910.1 - 2.8e-14 52.4 7.1 7e-14 51.1 4.9 1.7 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.1 XP_011271910.1 - 3.6e-12 46.8 2.6 0.0032 17.4 0.3 4.3 2 2 1 3 3 3 3 AAA domain SMC_N PF02463.14 XP_011271910.1 - 1.1e-09 37.8 2.5 0.011 14.9 0.1 4.0 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain Fer4 PF00037.22 XP_011271910.1 - 4.3e-08 32.4 3.2 4.3e-08 32.4 2.2 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_17 PF13207.1 XP_011271910.1 - 3.5e-06 27.8 0.3 0.053 14.3 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_15 PF13175.1 XP_011271910.1 - 4.3e-06 26.0 0.0 0.51 9.3 0.0 4.3 4 1 1 5 5 5 1 AAA ATPase domain Fer4_6 PF12837.2 XP_011271910.1 - 1e-05 25.1 2.1 1e-05 25.1 1.4 2.6 2 0 0 2 2 2 1 4Fe-4S binding domain AAA PF00004.24 XP_011271910.1 - 1.3e-05 25.3 0.0 0.05 13.8 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 XP_011271910.1 - 5.5e-05 23.3 0.0 0.05 13.7 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 XP_011271910.1 - 5.6e-05 23.1 0.4 0.018 15.0 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 XP_011271910.1 - 9.3e-05 21.6 1.1 0.32 10.1 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 XP_011271910.1 - 0.00014 21.3 0.2 0.14 11.7 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.1 XP_011271910.1 - 0.00015 22.0 0.0 0.59 10.4 0.0 2.9 2 1 0 2 2 2 2 AAA domain Fer4_21 PF14697.1 XP_011271910.1 - 0.00053 19.7 12.3 0.0012 18.6 8.6 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.2 XP_011271910.1 - 0.0007 19.3 2.4 0.0007 19.3 1.6 2.7 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_7 PF12838.2 XP_011271910.1 - 0.00095 19.4 1.7 0.00095 19.4 1.2 2.6 1 1 2 3 3 3 2 4Fe-4S dicluster domain VirE PF05272.6 XP_011271910.1 - 0.0011 18.4 0.0 0.82 9.1 0.0 2.6 2 0 0 2 2 2 1 Virulence-associated protein E UPF0079 PF02367.12 XP_011271910.1 - 0.0014 18.2 0.1 0.019 14.6 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 NB-ARC PF00931.17 XP_011271910.1 - 0.0018 17.2 0.0 0.06 12.1 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain AAA_33 PF13671.1 XP_011271910.1 - 0.0025 17.6 0.1 0.44 10.4 0.0 2.6 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 XP_011271910.1 - 0.0025 17.9 0.0 0.64 10.2 0.0 2.7 2 0 0 2 2 2 1 RNA helicase Fer4_10 PF13237.1 XP_011271910.1 - 0.0028 17.4 1.3 0.0028 17.4 0.9 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain AAA_25 PF13481.1 XP_011271910.1 - 0.0029 17.0 0.0 3 7.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 XP_011271910.1 - 0.0034 17.0 0.3 0.98 9.1 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Fer4_16 PF13484.1 XP_011271910.1 - 0.0038 17.9 0.1 0.0038 17.9 0.1 2.8 2 1 1 3 3 1 1 4Fe-4S double cluster binding domain SRP54 PF00448.17 XP_011271910.1 - 0.0043 16.5 1.1 0.59 9.5 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain NACHT PF05729.7 XP_011271910.1 - 0.0053 16.4 0.7 0.94 9.1 0.0 2.5 2 0 0 2 2 2 1 NACHT domain Fer4_3 PF12798.2 XP_011271910.1 - 0.0062 17.0 5.0 0.0062 17.0 3.4 2.6 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_9 PF13187.1 XP_011271910.1 - 0.0095 16.1 12.6 0.038 14.2 8.8 2.0 1 1 0 1 1 1 1 4Fe-4S dicluster domain Miro PF08477.8 XP_011271910.1 - 0.012 16.0 0.0 6.1 7.3 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein AAA_5 PF07728.9 XP_011271910.1 - 0.013 15.2 0.5 0.17 11.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_13 PF13166.1 XP_011271910.1 - 0.014 13.9 0.3 0.061 11.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain Fer4_8 PF13183.1 XP_011271910.1 - 0.022 14.7 7.4 0.065 13.2 5.2 1.7 1 1 0 1 1 1 0 4Fe-4S dicluster domain SbcCD_C PF13558.1 XP_011271910.1 - 0.031 14.1 0.0 5.3 7.0 0.0 3.1 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit PduV-EutP PF10662.4 XP_011271910.1 - 0.042 13.3 1.2 0.92 8.9 0.0 3.1 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Fer4_17 PF13534.1 XP_011271910.1 - 0.049 13.9 0.7 0.049 13.9 0.5 2.6 1 1 1 2 2 2 0 4Fe-4S dicluster domain AAA_30 PF13604.1 XP_011271910.1 - 0.081 12.4 0.0 2.1 7.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 XP_011271910.1 - 0.1 12.5 0.2 20 5.0 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 XP_011271910.1 - 0.12 11.8 0.1 3.5 7.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.12 XP_011271910.1 - 0.18 11.1 1.4 12 5.2 0.0 3.0 4 0 0 4 4 2 0 Thymidylate kinase Fer4_4 PF12800.2 XP_011271910.1 - 0.24 11.8 13.2 0.045 14.1 1.6 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain AAA_23 PF13476.1 XP_011271910.1 - 0.26 11.5 5.3 0.79 10.0 0.1 2.7 2 1 0 2 2 2 0 AAA domain Fer4_18 PF13746.1 XP_011271910.1 - 5.8 7.4 10.4 0.34 11.3 2.9 2.1 1 1 0 2 2 1 0 4Fe-4S dicluster domain Fer4_15 PF13459.1 XP_011271910.1 - 7.1 7.2 8.6 0.11 13.0 0.7 2.0 2 0 0 2 2 1 0 4Fe-4S single cluster domain DUF869 PF05911.6 XP_011271911.1 - 0.11 10.7 10.5 0.012 13.8 0.6 2.4 2 1 0 2 2 2 0 Plant protein of unknown function (DUF869) RRM_1 PF00076.17 XP_011271912.1 - 7.4e-85 278.6 5.9 1.8e-21 75.5 0.1 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 XP_011271912.1 - 3.3e-60 199.9 0.4 4.6e-16 58.5 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 XP_011271912.1 - 3.3e-47 158.1 0.1 1.5e-10 40.7 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 XP_011271912.1 - 1.9e-25 88.2 0.2 6.5e-25 86.6 0.2 2.0 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_3 PF08777.6 XP_011271912.1 - 1.9e-06 27.6 5.7 0.45 10.3 0.0 4.3 3 1 1 4 4 4 3 RNA binding motif Nup35_RRM_2 PF14605.1 XP_011271912.1 - 0.00033 20.3 0.1 19 5.1 0.0 4.2 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 XP_011271912.1 - 0.00053 19.6 1.9 0.64 9.8 0.0 4.0 3 1 1 4 4 4 1 Limkain b1 OB_RNB PF08206.6 XP_011271912.1 - 0.0013 18.2 0.3 9.4 5.8 0.0 3.5 3 0 0 3 3 3 1 Ribonuclease B OB domain CbiG_mid PF11761.3 XP_011271912.1 - 0.0057 16.8 0.0 18 5.6 0.0 3.4 3 0 0 3 3 3 0 Cobalamin biosynthesis central region YflT PF11181.3 XP_011271912.1 - 0.096 12.8 10.3 0.062 13.4 0.9 4.1 5 0 0 5 5 5 0 Heat induced stress protein YflT G_glu_transpept PF01019.16 XP_011271914.1 - 4.2e-126 421.4 0.0 4.8e-126 421.2 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase MFS_1 PF07690.11 XP_011271915.1 - 1.2e-35 122.9 37.6 1.5e-28 99.5 17.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 XP_011271915.1 - 2.7e-05 22.9 35.0 0.009 14.6 11.5 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.2 XP_011271915.1 - 0.0014 18.3 0.3 0.0014 18.3 0.2 3.9 4 0 0 4 4 4 1 MFS_1 like family MFS_1 PF07690.11 XP_011271917.1 - 7.8e-32 110.3 30.4 1.5e-26 92.9 14.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 XP_011271917.1 - 8.9e-09 34.2 7.9 8.9e-09 34.2 5.5 2.4 1 1 1 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.19 XP_011271917.1 - 1.8e-06 26.8 32.9 0.00017 20.2 9.8 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 XP_011271918.1 - 1.5e-30 106.0 20.8 1.5e-30 106.0 14.4 1.9 1 1 0 2 2 2 1 Major Facilitator Superfamily RasGEF PF00617.14 XP_011271919.1 - 1e-45 155.7 2.9 4.1e-45 153.8 2.0 2.1 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 XP_011271919.1 - 1.9e-11 43.9 2.2 1.9e-11 43.9 1.6 3.5 3 1 0 3 3 3 1 RasGEF N-terminal motif Flocculin_t3 PF13928.1 XP_011271920.1 - 0.0012 18.9 11.1 0.0012 18.9 7.7 2.9 2 0 0 2 2 2 1 Flocculin type 3 repeat Rib PF08428.5 XP_011271923.1 - 0.084 12.6 0.1 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 Rib/alpha-like repeat Alg14 PF08660.6 XP_011271925.1 - 0.067 13.1 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Oligosaccharide biosynthesis protein Alg14 like DUF1688 PF07958.6 XP_011271928.1 - 1.2e-159 531.3 0.0 1.4e-159 531.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) Ribosomal_S10 PF00338.17 XP_011271929.1 - 4.7e-27 93.6 1.2 5.7e-27 93.4 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DUF3929 PF13066.1 XP_011271929.1 - 0.17 11.6 0.5 9.6 6.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3929) Glyco_transf_15 PF01793.11 XP_011271930.1 - 1.3e-130 435.1 16.4 1.7e-130 434.7 11.4 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Baculo_VP91_N PF08475.5 XP_011271930.1 - 0.012 14.9 1.2 0.097 12.0 0.1 2.4 2 0 0 2 2 2 0 Viral capsid protein 91 N-terminal adh_short PF00106.20 XP_011271931.1 - 6.2e-63 211.6 3.3 3.3e-32 111.7 0.2 2.3 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 XP_011271931.1 - 2.1e-30 105.7 0.9 4.8e-16 58.9 0.0 2.2 2 0 0 2 2 2 2 KR domain MaoC_dehydratas PF01575.14 XP_011271931.1 - 3.3e-25 87.8 0.0 7e-25 86.7 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain NAD_binding_10 PF13460.1 XP_011271931.1 - 0.0085 16.1 1.1 0.072 13.0 0.8 2.4 1 1 0 1 1 1 1 NADH(P)-binding Nucleoplasmin PF03066.10 XP_011271931.1 - 0.046 13.2 2.0 0.1 12.1 1.4 1.5 1 0 0 1 1 1 0 Nucleoplasmin THF_DHG_CYH_C PF02882.14 XP_011271931.1 - 0.087 11.8 2.0 5.4 6.0 0.1 2.6 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.13 XP_011271931.1 - 0.56 9.8 4.8 7.1 6.2 0.2 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NOA36 PF06524.7 XP_011271931.1 - 5.3 6.2 4.6 9.8 5.3 3.2 1.3 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.4 XP_011271931.1 - 7.8 5.1 7.9 13 4.4 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Transp_cyt_pur PF02133.10 XP_011271932.1 - 1.5e-135 452.1 38.2 1.8e-135 451.9 26.5 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Transp_cyt_pur PF02133.10 XP_011271933.1 - 9.3e-140 466.0 39.3 1.1e-139 465.8 27.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Transp_cyt_pur PF02133.10 XP_011271934.1 - 5.2e-133 443.8 38.0 5.9e-133 443.6 26.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Amidohydro_4 PF13147.1 XP_011271935.1 - 6.4e-22 78.8 0.0 1.3e-21 77.8 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 XP_011271935.1 - 8.4e-18 65.1 0.6 7.8e-17 61.9 0.4 2.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 XP_011271935.1 - 4.6e-14 51.9 1.6 1.4e-13 50.4 1.1 1.9 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 XP_011271935.1 - 2.3e-10 40.2 0.0 4.9e-07 29.3 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Urease_alpha PF00449.15 XP_011271935.1 - 0.028 14.5 0.2 0.096 12.8 0.1 1.9 1 0 0 1 1 1 0 Urease alpha-subunit, N-terminal domain Peptidase_M20 PF01546.23 XP_011271936.1 - 4.4e-28 98.0 0.0 5.6e-28 97.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 XP_011271936.1 - 1.3e-09 37.8 0.0 3.1e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 XP_011271936.1 - 0.0038 16.9 0.0 0.0075 16.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 KMP11 PF03037.11 XP_011271936.1 - 0.0039 17.7 1.3 0.0074 16.8 0.9 1.4 1 0 0 1 1 1 1 Kinetoplastid membrane protein 11 Fungal_trans_2 PF11951.3 XP_011271937.1 - 1.9e-08 33.3 5.5 2.8e-07 29.4 3.8 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 XP_011271937.1 - 1e-05 25.3 13.8 2e-05 24.3 9.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LicD PF04991.8 XP_011271938.1 - 3.4e-25 89.3 7.0 3.4e-25 89.3 4.9 3.5 2 2 1 3 3 3 1 LicD family QCR10 PF09796.4 XP_011271939.1 - 3e-25 87.6 0.1 3.8e-25 87.3 0.1 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) UCR_6-4kD PF08997.5 XP_011271939.1 - 0.051 13.2 0.3 0.088 12.5 0.2 1.5 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein Mannosyl_trans3 PF11051.3 XP_011271940.1 - 1.4e-64 218.0 0.1 1.4e-64 218.0 0.1 2.2 3 0 0 3 3 3 1 Mannosyltransferase putative GST_C PF00043.20 XP_011271941.1 - 5e-12 45.6 0.0 7.7e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 XP_011271941.1 - 8.3e-12 45.1 0.0 1.8e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 XP_011271941.1 - 4.7e-09 36.1 0.0 8.7e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 XP_011271941.1 - 4.5e-07 29.9 0.0 8.4e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 XP_011271941.1 - 1.9e-05 24.4 0.0 3e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 XP_011271941.1 - 0.00022 21.6 0.1 0.00052 20.4 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Bac_luciferase PF00296.15 XP_011271942.1 - 1.4e-49 168.8 0.0 1.9e-49 168.4 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Bac_luciferase PF00296.15 XP_011271943.1 - 2.1e-54 184.7 0.0 2.8e-54 184.3 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Bac_luciferase PF00296.15 XP_011271944.1 - 6.7e-53 179.7 0.0 9.4e-53 179.3 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase TPP_enzyme_M PF00205.17 XP_011271945.1 - 1.9e-36 124.8 0.1 1.7e-35 121.7 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_N PF02776.13 XP_011271945.1 - 1.4e-33 115.8 0.0 2.7e-33 114.8 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 XP_011271945.1 - 2.4e-16 59.6 0.0 4.3e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CO_dh PF02552.11 XP_011271945.1 - 0.042 13.3 0.0 0.13 11.8 0.0 1.8 2 0 0 2 2 2 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit USP7_C2 PF14533.1 XP_011271946.1 - 3.4e-59 199.8 4.1 3.4e-59 199.8 2.8 3.8 4 1 1 5 5 5 1 Ubiquitin-specific protease C-terminal UCH PF00443.24 XP_011271946.1 - 1.6e-55 188.1 3.3 3.1e-55 187.1 2.3 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.3 XP_011271946.1 - 8.1e-47 159.5 0.7 8.1e-47 159.5 0.5 2.7 3 0 0 3 3 3 1 ICP0-binding domain of Ubiquitin-specific protease 7 UCH_1 PF13423.1 XP_011271946.1 - 4.3e-33 115.0 0.1 8.6e-33 114.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 XP_011271946.1 - 4.8e-15 55.8 3.9 2e-14 53.8 0.1 3.2 3 0 0 3 3 3 1 MATH domain CTP_transf_2 PF01467.21 XP_011271947.1 - 2.9e-10 40.4 0.1 9.7e-10 38.7 0.0 1.9 1 1 0 1 1 1 1 Cytidylyltransferase MIF4G PF02854.14 XP_011271948.1 - 3.9e-27 95.0 7.1 4.5e-27 94.8 3.7 2.0 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 XP_011271948.1 - 1.8e-20 72.7 1.0 4.2e-20 71.5 0.0 2.2 2 0 0 2 2 2 1 MA3 domain Glyco_hydro_32N PF00251.15 XP_011271948.1 - 0.061 12.6 0.6 0.3 10.3 0.0 2.0 1 1 1 2 2 2 0 Glycosyl hydrolases family 32 N-terminal domain DUF605 PF04652.11 XP_011271948.1 - 1.5 8.1 9.5 0.02 14.3 1.6 1.5 2 0 0 2 2 2 0 Vta1 like Glyco_hydro_17 PF00332.13 XP_011271949.1 - 6.6e-06 25.3 0.2 1.4e-05 24.2 0.2 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 DUF4347 PF14252.1 XP_011271949.1 - 0.001 18.5 0.1 0.0047 16.4 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4347) Telomere_Sde2 PF13019.1 XP_011271949.1 - 0.27 10.9 1.7 0.53 9.9 1.2 1.4 1 0 0 1 1 1 0 Telomere stability and silencing TMEM171 PF15471.1 XP_011271949.1 - 0.57 8.9 4.3 1 8.0 0.0 2.1 2 0 0 2 2 2 0 Transmembrane protein family 171 Glucan_synthase PF02364.10 XP_011271950.1 - 0 1345.8 0.2 0 1344.5 0.1 1.7 1 1 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 XP_011271950.1 - 8.6e-38 128.8 0.4 2.3e-37 127.5 0.3 1.8 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Glyco_hydro_72 PF03198.9 XP_011271951.1 - 6.9e-141 468.7 9.9 8.8e-141 468.4 6.9 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 XP_011271951.1 - 4.4e-27 94.3 2.0 1.2e-26 93.0 1.4 1.8 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.13 XP_011271951.1 - 0.00014 21.1 1.2 0.0026 17.0 0.8 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Rot1 PF10681.4 XP_011271953.1 - 2e-94 314.8 0.0 2.3e-94 314.6 0.0 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal DUF2718 PF10918.3 XP_011271954.1 - 0.0074 16.3 0.5 0.011 15.8 0.3 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2718) DUF1510 PF07423.6 XP_011271954.1 - 0.012 14.9 0.4 0.014 14.7 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) HMA PF00403.21 XP_011271955.1 - 9e-12 44.9 0.1 1.5e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Heavy-metal-associated domain Sod_Cu PF00080.15 XP_011271955.1 - 3.7e-05 23.9 0.0 8.3e-05 22.7 0.0 1.5 1 1 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) CorA PF01544.13 XP_011271956.1 - 1.3e-41 142.5 3.9 7.2e-21 74.4 0.0 3.5 4 0 0 4 4 4 3 CorA-like Mg2+ transporter protein PC4 PF02229.11 XP_011271957.1 - 0.037 13.2 0.0 0.06 12.5 0.0 1.3 1 0 0 1 1 1 0 Transcriptional Coactivator p15 (PC4) Aldo_ket_red PF00248.16 XP_011271958.1 - 7.8e-52 175.8 0.0 9.2e-52 175.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_tranf_2_5 PF13712.1 XP_011271958.1 - 0.13 11.5 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family Bap31 PF05529.7 XP_011271959.1 - 1.5e-31 109.3 12.9 4.2e-31 107.9 8.9 1.6 1 1 0 1 1 1 1 B-cell receptor-associated protein 31-like Tropomyosin_1 PF12718.2 XP_011271959.1 - 0.0014 18.4 10.1 0.0018 18.1 7.0 1.2 1 0 0 1 1 1 1 Tropomyosin like Ead_Ea22 PF13935.1 XP_011271959.1 - 0.0016 18.7 0.1 0.0019 18.5 0.1 1.2 1 0 0 1 1 1 1 Ead/Ea22-like protein SlyX PF04102.7 XP_011271959.1 - 0.0034 17.7 0.5 0.0056 17.0 0.3 1.3 1 0 0 1 1 1 1 SlyX DUF4446 PF14584.1 XP_011271959.1 - 0.0037 17.1 0.2 0.0057 16.4 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4446) IncA PF04156.9 XP_011271959.1 - 0.0052 16.3 0.2 0.0087 15.6 0.2 1.5 1 0 0 1 1 1 1 IncA protein DUF4047 PF13256.1 XP_011271959.1 - 0.016 15.1 0.8 0.025 14.5 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) Tektin PF03148.9 XP_011271959.1 - 0.022 13.3 2.9 0.028 12.9 2.0 1.1 1 0 0 1 1 1 0 Tektin family TBPIP PF07106.8 XP_011271959.1 - 0.026 14.0 6.2 0.039 13.4 4.3 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) NTase_sub_bind PF08780.6 XP_011271959.1 - 0.089 12.5 2.0 0.17 11.6 0.7 2.0 1 1 1 2 2 2 0 Nucleotidyltransferase substrate binding protein like CRA PF06589.6 XP_011271959.1 - 0.11 11.8 1.2 0.18 11.1 0.8 1.4 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) DivIC PF04977.10 XP_011271959.1 - 1.2 8.6 6.0 2.6 7.5 4.1 1.7 1 1 0 1 1 1 0 Septum formation initiator AAA_23 PF13476.1 XP_011271959.1 - 2.7 8.2 12.4 3.8 7.7 8.6 1.2 1 1 0 1 1 1 0 AAA domain V_ATPase_I PF01496.14 XP_011271959.1 - 6.2 4.5 8.8 0.67 7.7 2.5 1.7 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family EMP70 PF02990.11 XP_011271960.1 - 3e-60 204.1 19.6 4.1e-60 203.7 13.6 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 DUF4231 PF14015.1 XP_011271960.1 - 3.4 7.6 7.3 0.53 10.2 0.8 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) DUF3336 PF11815.3 XP_011271961.1 - 1.3e-39 134.9 3.7 1.3e-39 134.9 2.6 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.17 XP_011271961.1 - 4.6e-20 72.4 0.0 1.2e-19 71.0 0.0 1.8 1 0 0 1 1 1 1 Patatin-like phospholipase HAD_2 PF13419.1 XP_011271962.1 - 2.9e-21 76.4 0.0 4.1e-21 75.9 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 XP_011271962.1 - 0.00052 20.4 0.0 0.00098 19.5 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HrcA PF01628.16 XP_011271962.1 - 0.012 15.2 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 0 HrcA protein C terminal domain Hydrolase_like PF13242.1 XP_011271962.1 - 0.039 13.6 0.0 0.061 13.0 0.0 1.3 1 0 0 1 1 1 0 HAD-hyrolase-like Baculo_PEP_C PF04513.7 XP_011271962.1 - 0.054 13.3 1.0 0.074 12.8 0.1 1.7 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus PMSR PF01625.16 XP_011271962.1 - 0.067 13.0 0.4 0.16 11.8 0.3 1.6 1 1 0 1 1 1 0 Peptide methionine sulfoxide reductase UBA PF00627.26 XP_011271963.1 - 3.8e-20 71.1 3.3 2.8e-11 42.9 0.1 2.5 2 0 0 2 2 2 2 UBA/TS-N domain XPC-binding PF09280.6 XP_011271963.1 - 4.4e-16 58.0 5.7 4.4e-16 58.0 4.0 2.0 3 0 0 3 3 3 1 XPC-binding domain ubiquitin PF00240.18 XP_011271963.1 - 4.7e-16 57.9 2.7 8.2e-16 57.1 1.9 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 XP_011271963.1 - 4.1e-08 32.8 4.1 7.6e-08 31.9 2.8 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 XP_011271963.1 - 0.00037 20.3 0.1 0.00078 19.3 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ThiS PF02597.15 XP_011271963.1 - 0.068 13.6 0.6 3 8.3 0.0 2.5 2 0 0 2 2 2 0 ThiS family CUE PF02845.11 XP_011271963.1 - 0.073 12.5 0.2 2.7 7.5 0.0 3.4 4 0 0 4 4 4 0 CUE domain DUF2407 PF10302.4 XP_011271963.1 - 0.077 13.1 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain LRR_4 PF12799.2 XP_011271964.1 - 0.024 14.2 11.3 1.7 8.3 0.0 5.3 5 2 0 5 5 5 0 Leucine Rich repeats (2 copies) Nop14 PF04147.7 XP_011271964.1 - 0.051 11.5 15.7 0.07 11.0 10.5 1.5 2 0 0 2 2 2 0 Nop14-like family Daxx PF03344.10 XP_011271964.1 - 0.25 9.8 12.1 0.35 9.2 8.4 1.1 1 0 0 1 1 1 0 Daxx Family LRR_6 PF13516.1 XP_011271964.1 - 0.82 9.9 17.9 1.8 8.8 0.1 7.5 9 0 0 9 9 9 0 Leucine Rich repeat LRR_8 PF13855.1 XP_011271964.1 - 0.85 9.4 12.8 16 5.3 0.1 5.7 5 1 1 6 6 6 0 Leucine rich repeat DUF2201_N PF13203.1 XP_011271964.1 - 9.5 5.2 10.4 16 4.5 7.2 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain Ras PF00071.17 XP_011271966.1 - 8.1e-50 168.3 0.0 1.3e-49 167.7 0.0 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 XP_011271966.1 - 2.2e-16 60.4 0.0 4.8e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 XP_011271966.1 - 1.9e-06 27.2 0.0 3e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.4 XP_011271966.1 - 0.0027 17.1 0.0 0.44 10.0 0.0 2.3 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.22 XP_011271966.1 - 0.0042 16.5 0.1 0.014 14.8 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain G-alpha PF00503.15 XP_011271966.1 - 0.0053 15.5 0.0 0.017 13.8 0.0 1.7 1 1 0 2 2 2 1 G-protein alpha subunit Peptidase_S8 PF00082.17 XP_011271969.1 - 1.7e-52 178.3 8.0 3e-52 177.5 5.6 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 XP_011271969.1 - 1.7e-12 47.7 0.0 3.7e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 FPN1 PF06963.7 XP_011271970.1 - 1.1e-89 300.8 18.3 3.3e-89 299.2 12.7 1.6 1 1 0 1 1 1 1 Ferroportin1 (FPN1) CUE PF02845.11 XP_011271971.1 - 7.2e-07 28.5 0.2 1.5e-06 27.5 0.1 1.5 1 0 0 1 1 1 1 CUE domain DUF2360 PF10152.4 XP_011271971.1 - 4.7 7.4 14.5 0.49 10.6 3.1 2.9 3 0 0 3 3 3 0 Predicted coiled-coil domain-containing protein (DUF2360) WD40 PF00400.27 XP_011271972.1 - 0.0054 16.5 0.0 0.032 14.1 0.0 2.4 1 0 0 1 1 1 1 WD domain, G-beta repeat PQQ_3 PF13570.1 XP_011271972.1 - 0.15 12.3 0.0 0.92 9.8 0.0 2.4 2 0 0 2 2 2 0 PQQ-like domain WD40 PF00400.27 XP_011271973.1 - 2.2e-31 106.6 14.9 3.5e-08 33.0 0.0 5.6 6 0 0 6 6 6 5 WD domain, G-beta repeat Rav1p_C PF12234.3 XP_011271973.1 - 0.012 13.7 0.9 0.012 13.7 0.6 1.5 2 0 0 2 2 2 0 RAVE protein 1 C terminal BBS2_Mid PF14783.1 XP_011271973.1 - 0.073 12.8 0.2 9.2 6.0 0.0 3.3 4 1 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region Sec10 PF07393.6 XP_011271974.1 - 3.8e-57 194.0 27.4 6.4e-57 193.2 19.0 1.3 1 1 0 1 1 1 1 Exocyst complex component Sec10 Mannosyl_trans3 PF11051.3 XP_011271975.1 - 6.5e-58 196.2 0.6 1.5e-57 195.0 0.4 1.6 1 0 0 1 1 1 1 Mannosyltransferase putative Aminotran_1_2 PF00155.16 XP_011271976.1 - 1.1e-65 221.9 0.0 1.5e-65 221.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 XP_011271976.1 - 4.1e-07 29.4 0.0 5.5e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 XP_011271976.1 - 0.0017 17.1 0.0 0.0028 16.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V OKR_DC_1 PF01276.15 XP_011271976.1 - 0.024 13.1 0.0 0.04 12.4 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Glyco_hydro_72 PF03198.9 XP_011271977.1 - 4.7e-141 469.3 8.9 7.9e-141 468.5 6.2 1.3 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 XP_011271977.1 - 1.7e-25 89.3 7.6 5.2e-25 87.7 5.2 1.9 1 0 0 1 1 1 1 X8 domain G-patch PF01585.18 XP_011271978.1 - 3.8e-10 39.3 0.1 1.1e-09 37.8 0.1 1.9 1 0 0 1 1 1 1 G-patch domain SprA-related PF12118.3 XP_011271978.1 - 0.006 15.9 23.4 0.0076 15.6 16.2 1.3 1 0 0 1 1 1 1 SprA-related family MIP-T3 PF10243.4 XP_011271978.1 - 0.014 13.8 60.6 0.02 13.4 42.0 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 G-patch_2 PF12656.2 XP_011271978.1 - 0.025 14.4 0.1 0.025 14.4 0.1 4.6 2 1 1 3 3 2 0 DExH-box splicing factor binding site FLO_LFY PF01698.11 XP_011271978.1 - 0.41 9.4 27.7 0.56 8.9 19.2 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein BTV_NS2 PF04514.7 XP_011271978.1 - 2.8 6.7 30.5 3.9 6.2 21.1 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF2413 PF10310.4 XP_011271978.1 - 3.1 6.5 40.8 4.8 5.8 28.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) PLRV_ORF5 PF01690.12 XP_011271978.1 - 5.3 6.0 28.5 7 5.6 19.8 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Hex_IIIa PF02455.11 XP_011271978.1 - 5.3 5.6 16.6 6.5 5.3 11.5 1.3 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Hid1 PF12722.2 XP_011271978.1 - 7.4 4.1 27.7 8.8 3.8 19.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ycf1 PF05758.7 XP_011271978.1 - 8.4 3.9 32.7 11 3.5 22.6 1.2 1 0 0 1 1 1 0 Ycf1 HEAT_2 PF13646.1 XP_011271979.1 - 2e-23 82.4 11.0 8.9e-11 41.9 0.5 8.9 8 2 3 11 11 10 5 HEAT repeats HEAT PF02985.17 XP_011271979.1 - 3.4e-21 73.3 19.2 0.0015 18.3 0.0 12.5 14 0 0 14 14 11 5 HEAT repeat HEAT_EZ PF13513.1 XP_011271979.1 - 1.8e-18 66.4 25.4 5.3e-08 33.1 0.1 11.0 11 1 2 13 13 12 3 HEAT-like repeat MMS19_C PF12460.3 XP_011271979.1 - 2.1e-11 43.2 8.7 1.9e-06 26.8 1.5 4.3 4 1 1 5 5 5 3 RNAPII transcription regulator C-terminal Adaptin_N PF01602.15 XP_011271979.1 - 1e-08 33.9 5.2 0.0043 15.4 0.2 5.2 3 2 2 5 5 5 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 XP_011271979.1 - 2.9e-08 33.9 0.5 0.013 15.8 0.0 6.6 5 3 4 9 9 9 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 XP_011271979.1 - 9.5e-07 28.3 5.1 2 7.7 0.1 6.6 3 3 3 7 7 7 4 CLASP N terminal Xpo1 PF08389.7 XP_011271979.1 - 2e-06 27.7 9.0 0.00071 19.5 0.0 5.7 5 2 0 5 5 5 2 Exportin 1-like protein ParcG PF10274.4 XP_011271979.1 - 0.0002 21.3 0.9 0.25 11.2 0.0 3.8 4 0 0 4 4 4 2 Parkin co-regulated protein Arm PF00514.18 XP_011271979.1 - 0.0038 17.0 13.9 16 5.4 0.0 7.8 8 0 0 8 8 8 0 Armadillo/beta-catenin-like repeat DNA_alkylation PF08713.6 XP_011271979.1 - 0.023 14.2 0.0 0.24 10.8 0.0 2.8 3 0 0 3 3 3 0 DNA alkylation repair enzyme CBS PF00571.23 XP_011271980.1 - 5.9e-32 109.1 0.6 4.3e-09 36.0 0.0 4.3 4 0 0 4 4 4 4 CBS domain ABC_membrane PF00664.18 XP_011271981.1 - 2.4e-56 191.1 47.2 3.9e-30 105.2 12.8 2.7 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.22 XP_011271981.1 - 6e-42 143.1 7.4 2.9e-28 98.8 0.0 3.8 3 1 0 3 3 2 2 ABC transporter SMC_N PF02463.14 XP_011271981.1 - 3.2e-08 33.0 0.2 0.00022 20.5 0.0 3.9 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 XP_011271981.1 - 6.2e-07 28.8 0.7 0.025 14.0 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 XP_011271981.1 - 1.6e-06 28.9 0.1 0.014 16.2 0.0 3.4 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 XP_011271981.1 - 3.2e-05 23.1 1.1 0.21 10.7 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 XP_011271981.1 - 4.3e-05 23.4 1.2 0.011 15.6 0.1 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_23 PF13476.1 XP_011271981.1 - 0.00017 21.9 19.8 0.054 13.8 8.0 3.5 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 XP_011271981.1 - 0.00055 20.0 2.7 2.1 8.5 0.0 3.6 3 0 0 3 3 3 1 AAA domain Miro PF08477.8 XP_011271981.1 - 0.0009 19.7 0.6 2.6 8.5 0.0 3.0 2 0 0 2 2 2 2 Miro-like protein T2SE PF00437.15 XP_011271981.1 - 0.001 18.0 0.2 0.39 9.5 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein Zeta_toxin PF06414.7 XP_011271981.1 - 0.002 17.2 0.1 0.82 8.7 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin AAA_30 PF13604.1 XP_011271981.1 - 0.0025 17.4 3.7 1 8.8 0.0 3.2 4 0 0 4 4 3 2 AAA domain FtsK_SpoIIIE PF01580.13 XP_011271981.1 - 0.0033 16.9 0.2 0.13 11.7 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family Dynamin_N PF00350.18 XP_011271981.1 - 0.0036 17.1 7.8 0.55 10.0 0.1 3.6 3 0 0 3 3 3 1 Dynamin family AAA_10 PF12846.2 XP_011271981.1 - 0.0037 16.7 1.5 0.032 13.6 0.0 2.8 3 0 0 3 3 3 1 AAA-like domain PRK PF00485.13 XP_011271981.1 - 0.0064 16.0 0.4 0.79 9.2 0.0 2.6 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family ArgK PF03308.11 XP_011271981.1 - 0.0071 15.1 0.7 0.39 9.4 0.1 2.3 2 0 0 2 2 2 1 ArgK protein AAA_16 PF13191.1 XP_011271981.1 - 0.0071 16.3 0.7 0.52 10.2 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain TrwB_AAD_bind PF10412.4 XP_011271981.1 - 0.0094 14.6 0.6 1 7.9 0.1 2.3 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain SbcCD_C PF13558.1 XP_011271981.1 - 0.019 14.8 0.1 3.1 7.7 0.0 2.8 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit CDC45 PF02724.9 XP_011271981.1 - 0.066 11.2 2.7 0.12 10.3 1.9 1.3 1 0 0 1 1 1 0 CDC45-like protein cobW PF02492.14 XP_011271981.1 - 0.069 12.5 1.7 8.1 5.8 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 XP_011271981.1 - 0.081 13.2 11.7 0.31 11.3 0.0 4.1 5 0 0 5 5 3 0 AAA domain AAA_28 PF13521.1 XP_011271981.1 - 0.089 12.7 0.2 7.2 6.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 XP_011271981.1 - 0.1 12.4 0.1 0.1 12.4 0.1 2.9 3 0 0 3 3 2 0 Domain of unknown function DUF87 AAA_25 PF13481.1 XP_011271981.1 - 0.18 11.1 1.3 8.2 5.7 0.0 3.1 4 0 0 4 4 3 0 AAA domain AAA_19 PF13245.1 XP_011271981.1 - 0.2 11.4 0.1 1.3 8.8 0.0 2.3 2 0 0 2 2 2 0 Part of AAA domain RNA_helicase PF00910.17 XP_011271981.1 - 0.21 11.7 1.7 7.4 6.8 0.0 3.0 3 0 0 3 3 2 0 RNA helicase AAA_33 PF13671.1 XP_011271981.1 - 0.21 11.4 0.1 7 6.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain DnaJ PF00226.26 XP_011271982.1 - 2.9e-18 65.3 0.6 2.9e-18 65.3 0.4 2.3 2 0 0 2 2 2 1 DnaJ domain CAF-1_p150 PF11600.3 XP_011271982.1 - 2.2 7.5 33.7 0.33 10.2 20.6 1.6 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Neur_chan_memb PF02932.11 XP_011271982.1 - 3.3 7.5 4.6 6.7 6.5 3.2 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2348 PF09807.4 XP_011271983.1 - 9e-05 21.6 0.1 0.0011 18.0 0.1 2.3 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2348) DUF835 PF05763.7 XP_011271983.1 - 0.011 15.3 0.6 0.019 14.4 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF835) DUF3336 PF11815.3 XP_011271984.1 - 2.5e-37 127.6 0.8 5.2e-37 126.5 0.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 XP_011271984.1 - 1.6e-09 38.0 0.0 5.9e-09 36.1 0.0 1.9 2 0 0 2 2 2 1 Patatin-like phospholipase Arch_ATPase PF01637.13 XP_011271985.1 - 9.6e-12 45.0 0.4 9.6e-12 45.0 0.3 2.2 3 0 0 3 3 3 1 Archaeal ATPase AAA_16 PF13191.1 XP_011271985.1 - 6.6e-05 22.9 0.1 0.0056 16.6 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain KaiC PF06745.8 XP_011271985.1 - 0.013 14.6 0.1 0.028 13.5 0.1 1.6 1 0 0 1 1 1 0 KaiC AAA_25 PF13481.1 XP_011271985.1 - 0.035 13.4 0.0 0.082 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 XP_011271985.1 - 0.1 12.7 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain Methyltrn_RNA_3 PF02598.12 XP_011271986.1 - 7.7e-82 274.9 6.8 9e-82 274.6 4.7 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase Gsf2 PF11055.3 XP_011271987.1 - 5.9e-126 419.9 1.4 6.6e-126 419.8 1.0 1.0 1 0 0 1 1 1 1 Glucose signalling factor 2 CPSF_A PF03178.10 XP_011271988.1 - 1.2e-69 234.8 2.1 2.1e-69 234.0 1.5 1.4 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.4 XP_011271988.1 - 3.6e-63 213.4 3.8 6.6e-63 212.5 2.6 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Suc_Fer-like PF06999.7 XP_011271989.1 - 4.3e-42 144.7 0.0 6.7e-42 144.0 0.0 1.3 1 0 0 1 1 1 1 Sucrase/ferredoxin-like MFS_1 PF07690.11 XP_011271990.1 - 5e-37 127.4 46.4 1.2e-32 113.0 16.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 XP_011271990.1 - 1.7e-08 33.4 30.0 6.5e-08 31.5 20.8 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.2 XP_011271990.1 - 0.0035 17.1 0.1 0.0035 17.1 0.0 3.7 5 0 0 5 5 5 1 MFS_1 like family DUF4094 PF13334.1 XP_011271990.1 - 0.036 14.4 0.1 0.09 13.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) MFS_1 PF07690.11 XP_011271991.1 - 1.5e-32 112.7 29.8 2.5e-32 111.9 20.0 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 XP_011271991.1 - 2.6e-07 29.4 17.2 2.6e-07 29.4 11.9 2.5 1 1 1 2 2 2 1 MFS/sugar transport protein MFS_1_like PF12832.2 XP_011271991.1 - 0.0041 16.8 0.1 0.0041 16.8 0.1 3.7 4 1 0 4 4 4 1 MFS_1 like family Zn_clus PF00172.13 XP_011271992.1 - 3e-10 39.8 12.4 5.2e-10 39.0 8.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 XP_011271992.1 - 2.4e-05 23.3 0.2 5.9e-05 22.0 0.1 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Tyrosinase PF00264.15 XP_011271992.1 - 0.1 12.7 1.2 0.18 11.9 0.8 1.3 1 0 0 1 1 1 0 Common central domain of tyrosinase Vac14_Fab1_bd PF12755.2 XP_011271992.1 - 0.15 12.4 1.6 0.35 11.2 0.2 2.3 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region bZIP_1 PF00170.16 XP_011271992.1 - 0.39 10.6 9.2 0.29 11.1 0.5 2.6 2 0 0 2 2 2 0 bZIP transcription factor Ribosomal_L44 PF00935.14 XP_011271992.1 - 1.8 8.6 10.6 1.5 8.9 6.2 1.6 1 1 0 1 1 1 0 Ribosomal protein L44 HLH PF00010.21 XP_011271993.1 - 3.2e-15 55.5 3.7 3.2e-15 55.5 2.6 2.2 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF605 PF04652.11 XP_011271993.1 - 0.15 11.3 26.7 0.21 10.9 18.5 1.3 1 0 0 1 1 1 0 Vta1 like adh_short PF00106.20 XP_011271994.1 - 4.1e-13 49.5 0.0 1.1e-12 48.1 0.0 1.6 1 1 1 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 XP_011271994.1 - 1e-12 48.3 0.0 1.3e-12 47.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 XP_011271994.1 - 0.00018 21.2 0.0 0.0039 16.8 0.0 2.2 1 1 1 2 2 2 1 KR domain DUF1776 PF08643.5 XP_011271994.1 - 0.0018 17.4 0.3 0.79 8.7 0.1 2.2 2 0 0 2 2 2 2 Fungal family of unknown function (DUF1776) GatB_Yqey PF02637.13 XP_011271994.1 - 0.028 14.1 0.1 0.069 12.8 0.0 1.7 2 0 0 2 2 2 0 GatB domain CN_hydrolase PF00795.17 XP_011271995.1 - 6e-16 58.3 0.0 9.2e-16 57.7 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase LicD PF04991.8 XP_011271996.1 - 1.6e-39 136.1 4.6 1.6e-39 136.1 3.2 4.1 3 2 1 4 4 4 1 LicD family Pribosyl_synth PF14572.1 XP_011271997.1 - 9.2e-41 139.6 1.0 4.4e-31 108.0 0.0 2.2 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 XP_011271997.1 - 1.1e-39 134.8 0.0 2.8e-39 133.4 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 XP_011271997.1 - 2.8e-08 33.5 0.1 0.00093 18.9 0.0 2.4 2 0 0 2 2 2 2 Phosphoribosyl transferase domain His_Phos_2 PF00328.17 XP_011271998.1 - 7.7e-120 400.3 1.2 9.9e-120 400.0 0.8 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 XP_011271998.1 - 1.4e-05 24.6 0.0 2.9e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Utp21 PF04192.7 XP_011271999.1 - 3.7e-75 252.0 0.1 5.5e-75 251.5 0.1 1.3 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 XP_011271999.1 - 3.9e-20 70.9 4.1 1e-10 41.0 0.1 6.8 6 1 0 6 6 6 4 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 XP_011271999.1 - 0.00051 18.4 0.0 0.0089 14.3 0.0 2.6 2 0 0 2 2 2 1 Cytochrome D1 heme domain Utp12 PF04003.7 XP_011271999.1 - 0.0033 17.3 0.0 0.0067 16.3 0.0 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family Vps39_1 PF10366.4 XP_011272000.1 - 6.5e-27 93.6 0.7 6.5e-27 93.6 0.5 4.4 4 1 1 5 5 5 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 XP_011272000.1 - 2.9e-17 62.8 0.8 2.9e-17 62.8 0.5 2.9 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 2 DUF4050 PF13259.1 XP_011272001.1 - 2e-18 66.4 6.7 2e-18 66.4 4.6 2.5 2 2 0 2 2 2 1 Protein of unknown function (DUF4050) Rxt3 PF08642.5 XP_011272002.1 - 1.5e-27 96.1 0.9 5.6e-27 94.2 0.2 2.4 2 0 0 2 2 2 1 Histone deacetylation protein Rxt3 LCCL PF03815.14 XP_011272002.1 - 0.001 18.9 0.3 1.5 8.8 0.0 3.0 2 1 1 3 3 3 2 LCCL domain NAD_Gly3P_dh_N PF01210.18 XP_011272003.1 - 0.014 15.1 0.0 0.029 14.1 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Ribosomal_L31e PF01198.14 XP_011272004.1 - 7.7e-32 108.8 2.9 1.1e-31 108.3 2.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L31e Dus PF01207.12 XP_011272005.1 - 5.3e-78 261.9 0.0 6.5e-78 261.6 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.16 XP_011272005.1 - 0.00011 21.2 0.0 0.0021 17.0 0.0 2.0 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase Oxidored_FMN PF00724.15 XP_011272005.1 - 0.0019 17.2 0.1 0.0028 16.6 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family TMP-TENI PF02581.12 XP_011272005.1 - 0.0023 17.0 0.1 0.0043 16.1 0.0 1.4 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI His_biosynth PF00977.16 XP_011272005.1 - 0.0047 16.2 0.1 0.012 14.8 0.1 1.7 1 1 0 1 1 1 1 Histidine biosynthesis protein Resolvase PF00239.16 XP_011272005.1 - 0.0089 15.8 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 Resolvase, N terminal domain Dus PF01207.12 XP_011272006.1 - 4.9e-39 133.9 0.0 5.3e-38 130.6 0.0 2.1 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 XP_011272006.1 - 0.0019 17.8 4.1 0.0026 17.4 1.6 2.1 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Bap31 PF05529.7 XP_011272007.1 - 3.1e-53 180.0 10.6 1.4e-52 177.9 7.4 1.9 1 1 0 1 1 1 1 B-cell receptor-associated protein 31-like Pox_P21 PF05313.7 XP_011272007.1 - 0.076 12.2 0.9 0.11 11.6 0.6 1.3 1 0 0 1 1 1 0 Poxvirus P21 membrane protein DUF3847 PF12958.2 XP_011272007.1 - 1.8 8.3 5.1 0.33 10.7 0.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) zf-H2C2_2 PF13465.1 XP_011272008.1 - 0.00034 20.7 2.1 0.032 14.5 0.2 4.6 6 0 0 6 6 6 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 XP_011272008.1 - 0.0027 17.9 5.3 0.036 14.4 0.3 4.9 4 1 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.21 XP_011272008.1 - 0.051 13.9 1.0 0.051 13.9 0.7 5.2 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 XP_011272008.1 - 0.097 12.8 0.1 0.097 12.8 0.0 4.1 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Seipin PF06775.9 XP_011272009.1 - 1.2e-08 34.7 0.5 3.7e-08 33.1 0.3 1.9 1 1 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) DUF1765 PF08578.5 XP_011272010.1 - 2.6e-28 98.5 16.4 1e-27 96.6 6.3 3.8 3 0 0 3 3 3 2 Protein of unknown function (DUF1765) BRE1 PF08647.6 XP_011272011.1 - 2.6e-22 78.5 14.2 2.6e-22 78.5 9.8 7.4 5 3 3 8 8 8 1 BRE1 E3 ubiquitin ligase zf-C3HC4_2 PF13923.1 XP_011272011.1 - 5.6e-07 29.4 9.7 9.5e-07 28.7 6.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 XP_011272011.1 - 6.3e-07 28.9 8.3 1e-06 28.2 5.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 XP_011272011.1 - 1.7e-05 24.3 9.9 3.2e-05 23.4 6.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 XP_011272011.1 - 4e-05 23.2 9.6 6.9e-05 22.4 6.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 XP_011272011.1 - 0.00045 19.9 7.2 0.00078 19.2 5.0 1.4 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.1 XP_011272011.1 - 0.0033 16.9 2.4 0.0086 15.5 1.7 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C2H2 PF00096.21 XP_011272011.1 - 0.011 16.0 0.3 0.011 16.0 0.2 2.3 2 0 0 2 2 1 0 Zinc finger, C2H2 type zf-RING_UBOX PF13445.1 XP_011272011.1 - 0.012 15.2 4.8 0.04 13.6 3.3 2.0 1 0 0 1 1 1 0 RING-type zinc-finger NYD-SP28_assoc PF14775.1 XP_011272011.1 - 0.016 14.9 1.1 0.016 14.9 0.7 4.5 6 0 0 6 6 4 0 Sperm tail C-terminal domain HALZ PF02183.13 XP_011272011.1 - 0.029 14.0 0.2 0.029 14.0 0.2 8.6 7 2 1 8 8 8 0 Homeobox associated leucine zipper zf-RING_6 PF14835.1 XP_011272011.1 - 0.073 12.8 2.6 0.16 11.7 1.8 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-ribbon_3 PF13248.1 XP_011272011.1 - 0.22 10.7 1.7 0.41 9.9 1.2 1.5 1 0 0 1 1 1 0 zinc-ribbon domain zf-RING_4 PF14570.1 XP_011272011.1 - 1.2 8.8 7.9 2.3 7.8 5.5 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF1272 PF06906.6 XP_011272011.1 - 1.6 8.6 6.1 3.3 7.6 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-C3HC4_4 PF15227.1 XP_011272011.1 - 1.9 8.4 7.0 4 7.4 4.9 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C2H2_jaz PF12171.3 XP_011272011.1 - 2.1 8.5 7.0 2.5 8.3 0.1 3.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding FYVE PF01363.16 XP_011272011.1 - 2.2 8.2 11.5 56 3.7 8.0 2.5 1 1 0 1 1 1 0 FYVE zinc finger DZR PF12773.2 XP_011272011.1 - 4.9 7.0 9.3 29 4.6 6.8 1.9 1 1 0 1 1 1 0 Double zinc ribbon zf-C2H2_4 PF13894.1 XP_011272011.1 - 5.5 7.5 8.9 0.25 11.7 0.2 2.7 2 1 0 2 2 2 0 C2H2-type zinc finger Bromodomain PF00439.20 XP_011272012.1 - 2.6e-43 145.8 2.1 7.8e-21 73.8 0.1 2.6 2 0 0 2 2 2 2 Bromodomain DSHCT PF08148.7 XP_011272013.1 - 1.5e-59 200.2 1.1 3.5e-59 199.0 0.8 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 XP_011272013.1 - 6.6e-21 74.5 0.0 1.8e-20 73.1 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase rRNA_proc-arch PF13234.1 XP_011272013.1 - 9.6e-09 34.7 3.5 4e-08 32.7 2.4 2.0 1 1 0 1 1 1 1 rRNA-processing arch domain Helicase_C PF00271.26 XP_011272013.1 - 1.2e-05 25.0 0.0 5.2e-05 23.0 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Ribonucleas_3_3 PF14622.1 XP_011272014.1 - 0.022 14.7 0.5 0.066 13.1 0.3 1.8 1 1 1 2 2 2 0 Ribonuclease-III-like AAA PF00004.24 XP_011272015.1 - 1e-90 300.7 0.0 6.3e-44 149.3 0.0 2.7 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 XP_011272015.1 - 1.5e-13 51.1 0.5 1.9e-07 31.2 0.1 3.3 2 2 0 2 2 2 2 AAA ATPase domain RuvB_N PF05496.7 XP_011272015.1 - 1.7e-13 50.1 0.0 1.1e-05 24.6 0.0 3.3 3 1 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 XP_011272015.1 - 5.9e-12 45.4 0.0 3.7e-05 23.4 0.0 4.1 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 XP_011272015.1 - 8.9e-12 45.2 0.2 2.8e-05 24.2 0.0 4.6 2 2 0 2 2 2 2 AAA domain AAA_14 PF13173.1 XP_011272015.1 - 2.9e-09 36.9 0.0 7.7e-05 22.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 XP_011272015.1 - 4.3e-09 36.5 0.0 0.00063 19.6 0.0 3.0 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 XP_011272015.1 - 6.9e-08 33.3 0.0 0.00033 21.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 XP_011272015.1 - 2e-07 30.9 0.0 0.00013 21.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 XP_011272015.1 - 2.5e-07 29.7 0.0 0.0055 15.4 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_28 PF13521.1 XP_011272015.1 - 3.3e-06 27.1 0.0 0.0081 16.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 XP_011272015.1 - 3.3e-06 26.7 0.4 0.0019 17.9 0.1 3.1 2 0 0 2 2 2 1 Part of AAA domain Zeta_toxin PF06414.7 XP_011272015.1 - 3.8e-06 26.1 0.1 0.022 13.8 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin RNA_helicase PF00910.17 XP_011272015.1 - 8.1e-06 25.9 0.0 0.097 12.8 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_25 PF13481.1 XP_011272015.1 - 1.2e-05 24.8 3.9 0.37 10.1 0.1 3.9 2 2 1 3 3 3 2 AAA domain Sigma54_activ_2 PF14532.1 XP_011272015.1 - 2e-05 24.6 0.0 0.024 14.6 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 XP_011272015.1 - 5.8e-05 22.3 0.3 0.12 11.5 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 XP_011272015.1 - 0.00015 21.2 0.0 0.19 11.1 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein Bac_DnaA PF00308.13 XP_011272015.1 - 0.00017 21.3 0.0 0.0097 15.5 0.0 2.6 2 1 0 2 2 2 1 Bacterial dnaA protein NACHT PF05729.7 XP_011272015.1 - 0.00017 21.2 0.2 0.027 14.1 0.0 3.7 4 0 0 4 4 4 1 NACHT domain Arch_ATPase PF01637.13 XP_011272015.1 - 0.00024 20.8 0.0 1.1 8.9 0.0 3.4 2 2 1 3 3 3 2 Archaeal ATPase Rad17 PF03215.10 XP_011272015.1 - 0.0008 18.2 0.0 0.1 11.2 0.0 2.4 2 1 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_3 PF07726.6 XP_011272015.1 - 0.0014 18.2 0.0 1.5 8.4 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 XP_011272015.1 - 0.0019 17.8 0.7 0.16 11.5 0.0 3.1 4 0 0 4 4 3 1 AAA domain AAA_18 PF13238.1 XP_011272015.1 - 0.0024 18.1 0.0 0.11 12.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 XP_011272015.1 - 0.0037 16.8 0.0 0.33 10.4 0.0 2.6 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.22 XP_011272015.1 - 0.0048 17.2 0.2 0.2 11.9 0.0 2.9 4 0 0 4 4 2 1 ABC transporter DUF815 PF05673.8 XP_011272015.1 - 0.0062 15.4 0.0 0.16 10.8 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) CDC48_N PF02359.13 XP_011272015.1 - 0.0071 16.2 0.0 0.031 14.2 0.0 2.1 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain Sigma54_activat PF00158.21 XP_011272015.1 - 0.01 15.3 0.1 9.7 5.6 0.0 3.7 2 2 0 2 2 2 0 Sigma-54 interaction domain KaiC PF06745.8 XP_011272015.1 - 0.021 13.9 0.9 5.4 6.0 0.1 3.0 2 1 1 3 3 3 0 KaiC AAA_24 PF13479.1 XP_011272015.1 - 0.021 14.3 0.1 4.8 6.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 XP_011272015.1 - 0.022 14.2 0.0 0.45 9.9 0.0 2.8 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase UPF0079 PF02367.12 XP_011272015.1 - 0.028 14.0 0.2 1.1 8.8 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 NTPase_1 PF03266.10 XP_011272015.1 - 0.029 14.0 0.5 1.3 8.6 0.0 3.3 2 2 2 4 4 4 0 NTPase T2SE PF00437.15 XP_011272015.1 - 0.066 12.1 0.0 0.26 10.1 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein AFG1_ATPase PF03969.11 XP_011272015.1 - 0.069 11.9 0.0 0.37 9.5 0.0 2.1 2 0 0 2 2 2 0 AFG1-like ATPase WD40 PF00400.27 XP_011272017.1 - 1.2e-07 31.3 0.8 0.00078 19.2 0.1 3.6 2 1 0 2 2 2 2 WD domain, G-beta repeat UQ_con PF00179.21 XP_011272019.1 - 1.1e-43 148.0 0.0 1.2e-43 147.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 XP_011272019.1 - 0.00085 19.0 0.0 0.001 18.8 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 XP_011272019.1 - 0.13 12.1 0.8 0.39 10.6 0.5 1.8 1 1 0 1 1 1 0 RWD domain Pex19 PF04614.7 XP_011272020.1 - 7.9e-67 225.4 16.2 7.9e-67 225.4 11.2 1.3 1 1 0 1 1 1 1 Pex19 protein family DUF2573 PF10835.3 XP_011272020.1 - 0.12 12.4 2.4 7.3 6.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2573) Syntaxin PF00804.20 XP_011272020.1 - 2 8.6 10.1 0.082 13.0 2.1 2.3 2 1 0 2 2 2 0 Syntaxin Vac14_Fig4_bd PF11916.3 XP_011272021.1 - 2.4e-76 254.9 2.4 2.4e-76 254.9 1.6 1.8 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 XP_011272021.1 - 7.9e-49 164.0 1.8 5e-43 145.4 0.1 4.4 3 2 2 5 5 5 3 Vacuolar 14 Fab1-binding region HEAT PF02985.17 XP_011272021.1 - 1.3e-08 34.2 4.6 0.001 18.9 0.0 7.1 7 0 0 7 7 7 1 HEAT repeat HEAT_2 PF13646.1 XP_011272021.1 - 3.7e-08 33.5 2.5 0.0036 17.5 0.0 5.4 3 1 2 5 5 5 3 HEAT repeats HEAT_EZ PF13513.1 XP_011272021.1 - 6.2e-06 26.5 2.9 0.0047 17.3 0.1 5.6 6 0 0 6 6 6 1 HEAT-like repeat zf-C2H2_2 PF12756.2 XP_011272022.1 - 1.4e-32 111.8 2.2 1.5e-29 102.0 0.4 2.5 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 XP_011272022.1 - 0.037 14.1 1.5 0.037 14.1 1.1 2.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 XP_011272022.1 - 7.4 7.1 11.3 0.5 10.8 0.6 3.6 3 1 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.21 XP_011272022.1 - 9.1 6.8 7.8 0.87 10.0 0.5 3.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF663 PF04950.7 XP_011272023.1 - 2.3e-99 332.1 0.5 2.3e-99 332.1 0.4 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 XP_011272023.1 - 4.8e-24 83.6 0.0 1.3e-23 82.3 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain Peptidase_M16 PF00675.15 XP_011272024.1 - 2.6e-43 147.3 0.2 4.1e-42 143.4 0.1 2.6 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 XP_011272024.1 - 1.4e-35 122.6 1.7 1.2e-19 70.7 0.0 2.5 2 0 0 2 2 2 2 Peptidase M16 inactive domain Radial_spoke_3 PF06098.6 XP_011272024.1 - 0.00057 18.9 0.7 0.0019 17.2 0.5 1.9 1 0 0 1 1 1 1 Radial spoke protein 3 CFEM PF05730.6 XP_011272025.1 - 8.8e-08 31.8 14.8 2.2e-07 30.5 10.2 1.7 1 0 0 1 1 1 1 CFEM domain DUF605 PF04652.11 XP_011272025.1 - 0.097 12.0 32.4 0.12 11.7 22.4 1.1 1 0 0 1 1 1 0 Vta1 like DUF2201_N PF13203.1 XP_011272025.1 - 6.7 5.7 11.3 8.6 5.4 7.9 1.4 1 0 0 1 1 1 0 Putative metallopeptidase domain ATP-synt_10 PF05176.9 XP_011272026.1 - 4.3e-81 271.8 0.4 5.2e-81 271.6 0.3 1.0 1 0 0 1 1 1 1 ATP10 protein UPF0223 PF05256.7 XP_011272026.1 - 0.035 14.2 0.6 0.099 12.7 0.1 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0223) Iso_dh PF00180.15 XP_011272027.1 - 3e-70 236.8 0.0 3.6e-70 236.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase TSC22 PF01166.13 XP_011272028.1 - 0.019 14.9 0.5 0.073 13.0 0.3 2.0 1 0 0 1 1 1 0 TSC-22/dip/bun family HSBP1 PF06825.7 XP_011272028.1 - 0.049 13.1 0.2 0.11 12.0 0.2 1.6 1 0 0 1 1 1 0 Heat shock factor binding protein 1 CLASP_N PF12348.3 XP_011272029.1 - 7.2e-81 270.8 14.0 2.7e-66 223.1 0.2 3.2 3 0 0 3 3 3 2 CLASP N terminal HEAT PF02985.17 XP_011272029.1 - 0.061 13.4 0.1 34 4.8 0.0 4.3 3 0 0 3 3 3 0 HEAT repeat Fis1_TPR_N PF14852.1 XP_011272029.1 - 0.096 11.9 0.3 0.51 9.6 0.1 2.4 2 0 0 2 2 2 0 Fis1 N-terminal tetratricopeptide repeat MFS_1 PF07690.11 XP_011272030.1 - 1.4e-33 116.0 30.6 1.3e-24 86.5 10.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 XP_011272030.1 - 3.6e-05 22.4 11.5 3.6e-05 22.4 8.0 2.3 2 0 0 2 2 2 2 Vacuole effluxer Atg22 like Sugar_tr PF00083.19 XP_011272030.1 - 0.00027 19.6 15.4 0.0094 14.5 10.7 2.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.2 XP_011272030.1 - 0.0075 16.0 0.2 0.0075 16.0 0.1 3.1 4 0 0 4 4 4 1 MFS_1 like family MFS_3 PF05977.8 XP_011272030.1 - 0.019 13.1 17.2 0.34 8.9 1.0 3.5 1 1 2 4 4 4 0 Transmembrane secretion effector Bac_luciferase PF00296.15 XP_011272031.1 - 1.7e-52 178.4 0.0 2.2e-52 178.1 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Med17 PF10156.4 XP_011272032.1 - 1.7e-99 333.2 21.2 1.7e-99 333.2 14.7 1.4 2 0 0 2 2 2 1 Subunit 17 of Mediator complex Na_Ca_ex PF01699.19 XP_011272033.1 - 1.1e-41 141.7 44.1 3.2e-23 81.8 7.7 3.0 3 0 0 3 3 3 2 Sodium/calcium exchanger protein PfkB PF00294.19 XP_011272034.1 - 2.6e-67 227.1 0.2 3.2e-67 226.7 0.2 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 XP_011272034.1 - 0.00023 20.4 0.0 0.00041 19.6 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TRAM_LAG1_CLN8 PF03798.11 XP_011272035.1 - 3.7e-34 118.0 20.8 5.7e-34 117.3 14.4 1.3 1 0 0 1 1 1 1 TLC domain COX7C PF02935.11 XP_011272035.1 - 7 6.5 10.7 4.4 7.1 0.4 3.3 2 1 1 3 3 3 0 Cytochrome c oxidase subunit VIIc FAM176 PF14851.1 XP_011272036.1 - 0.56 9.8 3.0 1.4 8.5 2.1 1.6 1 0 0 1 1 1 0 FAM176 family RXT2_N PF08595.6 XP_011272036.1 - 2.6 7.8 23.4 0.092 12.5 10.0 2.9 3 0 0 3 3 3 0 RXT2-like, N-terminal Nucleoplasmin PF03066.10 XP_011272036.1 - 4.1 6.9 17.1 1.3 8.4 9.3 2.0 2 0 0 2 2 2 0 Nucleoplasmin NOA36 PF06524.7 XP_011272036.1 - 5.7 6.0 17.6 18 4.4 12.2 1.8 1 0 0 1 1 1 0 NOA36 protein TFIIA PF03153.8 XP_011272038.1 - 0.00082 19.3 11.8 0.0015 18.4 8.1 1.5 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Astro_capsid PF03115.9 XP_011272038.1 - 0.024 12.9 3.3 0.045 12.0 2.3 1.4 1 0 0 1 1 1 0 Astrovirus capsid protein precursor TRAP_alpha PF03896.11 XP_011272038.1 - 0.16 10.9 10.5 0.34 9.8 7.3 1.6 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Nop14 PF04147.7 XP_011272038.1 - 2.1 6.1 26.4 3.9 5.2 18.3 1.3 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 XP_011272038.1 - 5.1 5.4 19.2 8.9 4.6 13.3 1.3 1 0 0 1 1 1 0 Daxx Family Peptidase_M48 PF01435.13 XP_011272039.1 - 8.6e-53 179.2 0.0 1.3e-52 178.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.6 XP_011272039.1 - 0.0012 17.9 0.5 0.0026 16.7 0.3 1.6 1 0 0 1 1 1 1 BlaR1 peptidase M56 DUF2201_N PF13203.1 XP_011272039.1 - 0.032 13.3 0.1 0.054 12.6 0.1 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain SprT-like PF10263.4 XP_011272039.1 - 0.058 13.0 0.0 0.098 12.3 0.0 1.3 1 0 0 1 1 1 0 SprT-like family Peptidase_M57 PF12388.3 XP_011272039.1 - 0.091 12.0 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase DUF4538 PF15061.1 XP_011272039.1 - 0.97 8.7 5.7 0.22 10.8 0.3 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4538) FAD_binding_8 PF08022.7 XP_011272040.1 - 6.9e-20 70.8 0.2 1.3e-19 70.0 0.1 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 XP_011272040.1 - 1.5e-17 63.9 0.5 2.9e-17 63.0 0.0 1.7 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 XP_011272040.1 - 9.6e-16 58.0 14.6 9.6e-16 58.0 10.1 2.5 2 1 0 2 2 2 1 Ferric reductase like transmembrane component Trigger_N PF05697.8 XP_011272040.1 - 0.092 12.5 0.1 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial trigger factor protein (TF) NAD_binding_6 PF08030.7 XP_011272041.1 - 1.3e-21 77.1 0.0 2.7e-21 76.1 0.0 1.6 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 XP_011272041.1 - 4.2e-21 74.7 0.0 7.7e-21 73.9 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 XP_011272041.1 - 4.6e-15 55.8 19.1 8.8e-15 54.8 11.0 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 XP_011272041.1 - 0.045 14.3 0.0 0.2 12.2 0.0 2.2 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain DUF402 PF04167.8 XP_011272042.1 - 0.85 9.4 4.4 3.4 7.5 0.5 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF402) DUF4234 PF14018.1 XP_011272042.1 - 5.3 6.8 8.9 3.3 7.5 4.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) AAA PF00004.24 XP_011272043.1 - 1.9e-06 28.1 0.0 5.4e-06 26.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 XP_011272043.1 - 0.00054 19.1 0.0 0.0012 18.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 RNA_helicase PF00910.17 XP_011272043.1 - 0.012 15.7 2.2 0.83 9.8 0.0 3.6 3 0 0 3 3 3 0 RNA helicase AAA_14 PF13173.1 XP_011272043.1 - 0.013 15.3 1.4 0.036 13.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 XP_011272043.1 - 0.015 15.4 0.0 0.049 13.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain Hydantoinase_B PF02538.9 XP_011272043.1 - 0.034 12.4 0.1 0.058 11.6 0.0 1.3 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase ZYG-11_interact PF05884.7 XP_011272043.1 - 0.08 12.0 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Interactor of ZYG-11 TFIID-18kDa PF02269.11 XP_011272044.1 - 6.6e-34 115.5 0.3 3.3e-33 113.3 0.1 2.2 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit TPK_catalytic PF04263.11 XP_011272045.1 - 5.7e-21 74.3 0.0 6.6e-15 54.7 0.0 2.2 2 0 0 2 2 2 2 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 XP_011272045.1 - 3.8e-14 52.1 0.6 1.3e-12 47.2 0.1 2.4 2 0 0 2 2 2 1 Thiamin pyrophosphokinase, vitamin B1 binding domain AAA PF00004.24 XP_011272046.1 - 2.8e-45 153.7 0.0 7.7e-45 152.3 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 XP_011272046.1 - 2.7e-08 33.9 0.0 5.3e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 XP_011272046.1 - 2.4e-07 30.5 0.2 9.6e-07 28.6 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 XP_011272046.1 - 2.5e-06 27.6 0.8 0.00023 21.3 0.6 2.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 XP_011272046.1 - 2.6e-06 27.5 0.2 1.2e-05 25.3 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 XP_011272046.1 - 5.1e-05 23.1 0.1 0.00033 20.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 XP_011272046.1 - 0.00035 19.5 0.0 0.00075 18.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.7 XP_011272046.1 - 0.00072 18.6 0.0 0.0016 17.5 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 XP_011272046.1 - 0.0018 19.0 0.0 0.0068 17.2 0.0 2.0 2 0 0 2 2 1 1 AAA domain NTPase_1 PF03266.10 XP_011272046.1 - 0.002 17.8 0.0 0.0061 16.2 0.0 1.9 2 0 0 2 2 1 1 NTPase NACHT PF05729.7 XP_011272046.1 - 0.0021 17.7 0.3 0.064 12.9 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_19 PF13245.1 XP_011272046.1 - 0.0021 17.7 0.3 0.0058 16.3 0.2 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 XP_011272046.1 - 0.0024 17.7 0.0 0.0053 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 XP_011272046.1 - 0.0028 17.8 0.0 0.0062 16.6 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_24 PF13479.1 XP_011272046.1 - 0.0049 16.4 0.0 0.01 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 XP_011272046.1 - 0.0051 15.9 0.0 0.0097 15.0 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.1 XP_011272046.1 - 0.0053 16.7 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain UPF0079 PF02367.12 XP_011272046.1 - 0.0057 16.2 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_25 PF13481.1 XP_011272046.1 - 0.0075 15.6 0.9 0.11 11.8 0.1 2.4 1 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 XP_011272046.1 - 0.0082 15.3 0.1 0.02 14.0 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 XP_011272046.1 - 0.013 14.9 0.0 0.026 13.9 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.21 XP_011272046.1 - 0.013 15.0 0.1 0.19 11.1 0.0 2.4 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_30 PF13604.1 XP_011272046.1 - 0.014 14.9 0.0 0.03 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 XP_011272046.1 - 0.015 14.0 0.0 0.028 13.1 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus AAA_3 PF07726.6 XP_011272046.1 - 0.015 14.9 0.0 0.062 12.9 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 XP_011272046.1 - 0.024 14.9 1.2 1.8 8.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.1 XP_011272046.1 - 0.031 13.8 0.0 0.12 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 XP_011272046.1 - 0.037 13.7 1.9 0.24 11.0 0.0 2.7 2 1 1 3 3 3 0 Archaeal ATPase AAA_18 PF13238.1 XP_011272046.1 - 0.059 13.6 0.1 0.25 11.6 0.0 2.2 2 1 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.12 XP_011272046.1 - 0.12 11.2 0.0 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AATase PF07247.7 XP_011272047.1 - 5.3e-27 94.5 5.3 2.1e-26 92.5 3.6 1.9 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 XP_011272047.1 - 2e-09 36.7 0.0 3.6e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Condensation domain Prothymosin PF03247.9 XP_011272050.1 - 0.25 11.4 7.7 0.023 14.8 1.9 1.8 2 0 0 2 2 2 0 Prothymosin/parathymosin family DUF1479 PF07350.7 XP_011272051.1 - 2.5e-101 339.1 0.1 3.3e-60 203.7 0.1 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF1479) PhyH PF05721.8 XP_011272051.1 - 0.016 15.2 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) ABC2_membrane PF01061.19 XP_011272052.1 - 0.031 13.4 1.0 0.043 12.9 0.7 1.4 1 1 0 1 1 1 0 ABC-2 type transporter DUF1700 PF08006.6 XP_011272053.1 - 4.7 6.4 6.3 7.2 5.8 4.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) Bac_luciferase PF00296.15 XP_011272054.1 - 2.3e-52 178.0 0.0 3e-52 177.6 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase RVT_2 PF07727.9 XP_011272055.1 - 3e-31 108.2 0.4 5.8e-31 107.3 0.3 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 XP_011272055.1 - 3.9e-11 43.1 0.0 2.1e-09 37.5 0.0 2.8 2 0 0 2 2 2 1 Integrase core domain Suf PF05843.9 XP_011272056.1 - 6.2e-48 163.9 16.6 6.2e-48 163.9 11.5 4.1 3 1 0 3 3 3 1 Suppressor of forked protein (Suf) DUF2098 PF09871.4 XP_011272056.1 - 0.024 14.5 1.3 0.024 14.5 0.9 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2098) Fungal_trans_2 PF11951.3 XP_011272057.1 - 8.2e-57 192.5 3.4 1.2e-56 192.0 2.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 XP_011272057.1 - 5.4e-08 32.6 11.2 9.2e-08 31.8 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ASF1_hist_chap PF04729.8 XP_011272059.1 - 2.1e-67 225.5 0.1 3.8e-67 224.7 0.1 1.4 1 0 0 1 1 1 1 ASF1 like histone chaperone CDC45 PF02724.9 XP_011272059.1 - 1.8 6.4 14.9 2.4 6.1 10.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 XP_011272059.1 - 3.4 5.4 23.0 4.4 5.1 16.0 1.1 1 0 0 1 1 1 0 Nop14-like family Glyco_hydro_76 PF03663.9 XP_011272060.1 - 2.9e-139 464.5 9.7 3.7e-139 464.2 6.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_76 PF03663.9 XP_011272061.1 - 2.1e-143 478.1 15.7 2.6e-143 477.8 10.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_76 PF03663.9 XP_011272062.1 - 6.5e-126 420.6 13.0 7.7e-126 420.4 9.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_47 PF01532.15 XP_011272062.1 - 0.0029 16.3 0.2 0.061 11.9 0.0 2.4 2 1 0 2 2 2 1 Glycosyl hydrolase family 47 HAD_2 PF13419.1 XP_011272063.1 - 2.9e-14 53.6 0.0 4.3e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 XP_011272063.1 - 7.8e-09 35.1 0.0 1.1e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like DUF4448 PF14610.1 XP_011272064.1 - 8.2e-58 195.0 0.1 1.4e-57 194.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF3810 PF12725.2 XP_011272065.1 - 0.27 10.0 3.2 0.38 9.5 0.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3810) SNF2_N PF00176.18 XP_011272066.1 - 5.5e-66 222.3 0.1 8.6e-66 221.7 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 XP_011272066.1 - 5.4e-14 52.0 0.0 1.4e-13 50.7 0.0 1.7 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 XP_011272066.1 - 2.2e-12 46.6 0.0 7.2e-12 45.0 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 XP_011272066.1 - 3.4e-05 23.5 11.2 6.9e-05 22.5 7.8 1.6 1 0 0 1 1 1 1 Ring finger domain ResIII PF04851.10 XP_011272066.1 - 5.7e-05 23.0 0.0 0.00023 21.0 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.20 XP_011272066.1 - 7.3e-05 22.3 13.5 0.00014 21.4 9.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 XP_011272066.1 - 0.00017 21.2 12.8 0.00031 20.3 8.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 XP_011272066.1 - 0.00027 20.5 9.0 0.00047 19.7 6.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 XP_011272066.1 - 0.018 15.0 12.0 0.038 14.0 8.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 XP_011272066.1 - 0.047 13.5 11.0 0.1 12.5 7.6 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Patched PF02460.13 XP_011272066.1 - 0.058 11.3 0.1 0.11 10.3 0.0 1.4 1 0 0 1 1 1 0 Patched family zf-RING_4 PF14570.1 XP_011272066.1 - 0.44 10.1 9.7 0.98 9.0 6.7 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 XP_011272066.1 - 0.67 9.8 5.4 1.4 8.7 3.8 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger MOZ_SAS PF01853.13 XP_011272067.1 - 4.3e-59 198.9 3.4 6.1e-59 198.4 2.4 1.2 1 0 0 1 1 1 1 MOZ/SAS family HA2 PF04408.18 XP_011272068.1 - 3.8e-24 84.6 0.1 3.8e-24 84.6 0.0 3.7 4 1 0 4 4 4 1 Helicase associated domain (HA2) Helicase_C PF00271.26 XP_011272068.1 - 1.2e-12 47.4 0.0 5.4e-12 45.3 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 XP_011272068.1 - 1.5e-07 31.0 0.0 3.9e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.11 XP_011272068.1 - 2e-07 30.8 0.0 6e-07 29.2 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.1 XP_011272068.1 - 3.3e-06 27.2 0.5 7.9e-05 22.8 0.0 2.9 3 0 0 3 3 3 1 AAA domain KaiC PF06745.8 XP_011272068.1 - 0.0017 17.5 0.2 0.0089 15.1 0.0 2.2 2 0 0 2 2 2 1 KaiC T2SE PF00437.15 XP_011272068.1 - 0.018 13.9 0.0 0.038 12.8 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Nramp PF01566.13 XP_011272070.1 - 4.8e-97 324.9 9.5 7.8e-97 324.2 6.6 1.3 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein Lipase_3 PF01764.20 XP_011272073.1 - 2.1e-23 82.4 0.0 4.5e-23 81.4 0.0 1.5 1 1 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 XP_011272073.1 - 0.057 12.7 0.0 5.2 6.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) AFOR_C PF01314.13 XP_011272073.1 - 0.073 11.7 0.0 0.12 10.9 0.0 1.3 1 0 0 1 1 1 0 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 Adap_comp_sub PF00928.16 XP_011272074.1 - 1.7e-40 138.8 0.1 2.1e-32 112.2 0.0 2.2 1 1 1 2 2 2 2 Adaptor complexes medium subunit family CENP-B_dimeris PF09026.5 XP_011272074.1 - 0.21 11.8 11.0 0.18 12.0 2.6 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain PBP1_TM PF14812.1 XP_011272074.1 - 0.73 10.1 12.4 0.096 13.0 2.1 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.1 XP_011272074.1 - 4.8 6.8 6.0 1.7 8.3 0.9 2.2 2 0 0 2 2 2 0 FAM176 family Nucleoplasmin PF03066.10 XP_011272074.1 - 9.7 5.6 15.4 31 4.0 7.9 2.2 2 0 0 2 2 2 0 Nucleoplasmin Cu-oxidase_2 PF07731.9 XP_011272075.1 - 3.1e-45 153.0 8.3 8.7e-41 138.6 0.6 3.0 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 XP_011272075.1 - 4.3e-43 145.7 2.6 3.9e-39 133.0 0.5 3.4 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 XP_011272075.1 - 7e-33 113.7 3.4 4.2e-29 101.5 0.2 3.5 3 0 0 3 3 3 2 Multicopper oxidase PPC PF04151.10 XP_011272075.1 - 0.022 15.6 0.1 11 7.0 0.0 3.3 2 0 0 2 2 2 0 Bacterial pre-peptidase C-terminal domain DUF2258 PF10015.4 XP_011272075.1 - 0.1 12.4 0.0 2 8.2 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2258) Abhydrolase_6 PF12697.2 XP_011272076.1 - 2e-22 80.1 0.0 2.6e-22 79.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 XP_011272076.1 - 1.7e-13 50.6 0.0 4.1e-13 49.4 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 XP_011272076.1 - 2e-06 27.6 0.0 5.2e-06 26.2 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 XP_011272076.1 - 0.00072 19.0 0.2 0.096 12.1 0.0 2.6 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Ser_hydrolase PF06821.8 XP_011272076.1 - 0.0062 16.1 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase DUF2305 PF10230.4 XP_011272076.1 - 0.038 13.3 0.2 0.09 12.1 0.1 1.6 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) Ndr PF03096.9 XP_011272076.1 - 0.065 11.6 0.0 0.14 10.5 0.0 1.5 2 0 0 2 2 2 0 Ndr family AMP-binding PF00501.23 XP_011272077.1 - 1.7e-77 260.6 0.0 2.5e-77 260.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 XP_011272077.1 - 0.0028 18.5 0.0 0.0099 16.8 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain HTH_40 PF14493.1 XP_011272077.1 - 0.021 15.0 0.1 0.081 13.1 0.1 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain CBFD_NFYB_HMF PF00808.18 XP_011272078.1 - 6.9e-24 83.6 0.0 1.1e-23 83.0 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 XP_011272078.1 - 0.0004 20.4 0.6 0.00069 19.6 0.0 1.6 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Daxx PF03344.10 XP_011272078.1 - 0.0066 15.0 14.9 0.0086 14.6 10.3 1.1 1 0 0 1 1 1 1 Daxx Family TFIID-18kDa PF02269.11 XP_011272078.1 - 0.0077 16.0 0.0 0.025 14.3 0.0 1.8 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit TFIIA PF03153.8 XP_011272078.1 - 0.027 14.3 8.2 0.027 14.3 5.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TFIID_20kDa PF03847.8 XP_011272078.1 - 0.033 14.4 0.1 2.8 8.2 0.0 2.5 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A DUF1168 PF06658.7 XP_011272078.1 - 0.093 12.2 10.9 0.19 11.2 7.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Peptidase_S8 PF00082.17 XP_011272079.1 - 8e-33 113.7 0.7 1.2e-32 113.2 0.5 1.2 1 0 0 1 1 1 1 Subtilase family Occludin_ELL PF07303.8 XP_011272081.1 - 0.014 16.0 0.5 0.041 14.6 0.1 1.9 2 0 0 2 2 2 0 Occludin homology domain UBN2_2 PF14227.1 XP_011272081.1 - 0.032 13.7 4.3 0.021 14.3 1.1 1.9 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type Rsa3 PF14615.1 XP_011272081.1 - 0.045 13.0 0.5 0.18 11.1 0.3 2.2 1 1 0 1 1 1 0 Ribosome-assembly protein 3 A_thal_3526 PF09713.5 XP_011272081.1 - 0.047 13.8 0.1 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 Plant protein 1589 of unknown function (A_thal_3526) MA3 PF02847.12 XP_011272081.1 - 0.07 12.8 0.1 0.22 11.2 0.1 1.8 2 0 0 2 2 2 0 MA3 domain FlgN PF05130.7 XP_011272081.1 - 0.088 13.0 2.0 0.18 12.0 1.4 1.6 1 1 0 1 1 1 0 FlgN protein CENP-Q PF13094.1 XP_011272081.1 - 0.11 12.5 3.2 0.16 11.9 2.2 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF1664 PF07889.7 XP_011272081.1 - 0.13 12.0 0.5 0.24 11.1 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) eIF-3c_N PF05470.7 XP_011272081.1 - 0.14 10.2 2.9 0.2 9.7 2.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus YvrJ PF12841.2 XP_011272081.1 - 0.15 11.3 1.1 0.36 10.1 0.1 2.1 2 0 0 2 2 2 0 YvrJ protein family UPF0118 PF01594.11 XP_011272081.1 - 1.3 7.9 8.2 6.1 5.7 1.2 3.0 2 1 1 3 3 3 0 Domain of unknown function DUF20 Malate_synthase PF01274.17 XP_011272083.1 - 4.2e-218 724.6 0.0 4.8e-218 724.4 0.0 1.0 1 0 0 1 1 1 1 Malate synthase zf-RING_2 PF13639.1 XP_011272084.1 - 6.4e-12 45.0 4.5 1.1e-11 44.4 3.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 XP_011272084.1 - 9.3e-09 35.2 3.0 2.3e-08 34.0 2.1 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 XP_011272084.1 - 2e-08 33.7 7.6 3.8e-08 32.8 5.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 XP_011272084.1 - 7.9e-06 25.7 5.8 1.4e-05 25.0 4.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 XP_011272084.1 - 3.6e-05 23.3 2.9 5.9e-05 22.6 2.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 XP_011272084.1 - 0.00024 20.7 6.2 0.0004 20.0 4.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 XP_011272084.1 - 0.00063 19.5 2.4 0.0017 18.1 1.6 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 XP_011272084.1 - 0.0083 15.6 1.6 0.017 14.6 1.1 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.2 XP_011272084.1 - 0.0085 16.1 7.6 0.016 15.2 5.3 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING-like PF08746.6 XP_011272084.1 - 0.045 13.7 6.2 0.088 12.8 4.3 1.5 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.1 XP_011272084.1 - 0.12 11.9 5.1 0.24 11.0 3.5 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 XP_011272084.1 - 0.53 10.2 8.1 1.8 8.5 5.6 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.24 XP_011272084.1 - 0.93 9.2 5.5 1.8 8.3 3.8 1.5 1 0 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.1 XP_011272084.1 - 1.4 8.7 3.8 4 7.2 2.6 1.7 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 RRM_1 PF00076.17 XP_011272085.1 - 2.9e-09 36.4 1.6 0.0022 17.5 0.2 2.9 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 XP_011272085.1 - 1.7e-05 24.6 0.2 0.032 14.1 0.1 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 XP_011272085.1 - 0.002 17.9 0.2 0.014 15.2 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HSP70 PF00012.15 XP_011272086.1 - 1.3e-66 224.8 14.1 1.3e-66 224.8 9.8 3.1 2 1 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 XP_011272086.1 - 2.2e-06 26.5 0.0 1.7e-05 23.5 0.0 2.3 2 0 0 2 2 2 1 MreB/Mbl protein DUF2347 PF09804.4 XP_011272087.1 - 6.7e-74 248.6 0.5 1.1e-73 247.9 0.3 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.1 XP_011272087.1 - 5.1e-32 111.3 5.7 1.3e-30 106.7 3.9 2.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4484) Avl9 PF09794.4 XP_011272087.1 - 3.3e-06 25.8 0.3 0.041 12.3 0.0 2.2 2 0 0 2 2 2 2 Transport protein Avl9 Glyco_hydro_76 PF03663.9 XP_011272088.1 - 6.5e-152 506.1 19.3 8.3e-152 505.8 13.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 DUF572 PF04502.8 XP_011272089.1 - 5.3e-65 219.7 26.4 6.2e-65 219.5 18.3 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF951 PF06107.6 XP_011272089.1 - 0.023 14.2 0.5 0.68 9.4 0.0 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF951) zf-FPG_IleRS PF06827.9 XP_011272089.1 - 0.096 12.3 2.3 4.3 7.0 0.1 2.4 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS TF_Zn_Ribbon PF08271.7 XP_011272089.1 - 0.098 11.9 0.5 3.7 6.9 0.0 2.6 2 0 0 2 2 2 0 TFIIB zinc-binding zf-ribbon_3 PF13248.1 XP_011272089.1 - 0.11 11.7 0.4 2.6 7.3 0.0 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Mu-like_Com PF10122.4 XP_011272089.1 - 0.34 10.0 1.9 0.41 9.7 0.1 2.0 2 0 0 2 2 2 0 Mu-like prophage protein Com CLN3 PF02487.12 XP_011272090.1 - 1.5e-122 409.2 21.8 6.6e-115 384.1 8.7 2.0 1 1 1 2 2 2 2 CLN3 protein MFS_1 PF07690.11 XP_011272090.1 - 0.00017 20.4 1.9 0.00017 20.4 1.3 2.8 1 1 2 3 3 3 1 Major Facilitator Superfamily Ist1 PF03398.9 XP_011272091.1 - 1.1e-49 167.9 1.9 1.5e-49 167.5 1.3 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway TPR_11 PF13414.1 XP_011272092.1 - 5.1e-23 80.5 18.2 1.7e-05 24.3 0.1 7.7 7 1 2 9 9 9 4 TPR repeat TPR_16 PF13432.1 XP_011272092.1 - 1.2e-21 76.7 7.5 5.2e-06 26.9 0.0 7.0 5 1 3 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.12 XP_011272092.1 - 2.1e-19 67.8 21.6 0.0034 17.1 0.0 9.7 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_1 PF00515.23 XP_011272092.1 - 5.4e-19 66.9 21.5 1.4e-06 27.6 0.0 8.6 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_14 PF13428.1 XP_011272092.1 - 1.4e-14 53.2 3.3 0.025 15.1 0.0 8.2 6 2 3 9 9 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 XP_011272092.1 - 3.5e-13 49.6 11.0 1.4e-05 25.3 0.1 6.1 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 XP_011272092.1 - 5.4e-13 48.6 18.3 0.015 15.2 0.8 7.6 6 2 3 9 9 9 7 Tetratricopeptide repeat TPR_8 PF13181.1 XP_011272092.1 - 6.8e-13 47.3 18.5 0.021 14.5 0.0 9.1 9 1 1 10 10 9 5 Tetratricopeptide repeat TPR_6 PF13174.1 XP_011272092.1 - 5.5e-12 45.3 8.9 0.015 15.7 0.1 8.8 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_17 PF13431.1 XP_011272092.1 - 7.6e-09 35.0 7.5 0.079 13.2 0.0 7.7 9 0 0 9 9 6 2 Tetratricopeptide repeat Apc3 PF12895.2 XP_011272092.1 - 3.6e-07 30.2 13.6 0.0035 17.4 0.7 5.5 6 0 0 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 XP_011272092.1 - 1.4e-05 24.4 14.7 0.91 9.4 0.0 8.2 9 1 0 9 9 9 2 Tetratricopeptide repeat TPR_10 PF13374.1 XP_011272092.1 - 0.00029 20.6 13.9 7.1 6.7 0.1 7.9 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_3 PF07720.7 XP_011272092.1 - 0.003 17.3 6.1 0.011 15.4 0.2 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_15 PF13429.1 XP_011272092.1 - 0.019 14.0 10.3 0.19 10.7 0.5 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.1 XP_011272092.1 - 0.055 13.3 7.2 25 4.8 0.0 4.7 4 1 2 6 6 6 0 Tetratricopeptide repeat UFD1 PF03152.9 XP_011272093.1 - 9.9e-69 229.9 0.0 1.5e-68 229.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 DUF3290 PF11694.3 XP_011272093.1 - 0.0075 16.0 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3290) CDC48_N PF02359.13 XP_011272093.1 - 0.048 13.6 0.0 0.83 9.6 0.0 2.8 3 1 1 4 4 4 0 Cell division protein 48 (CDC48), N-terminal domain DUF2422 PF10337.4 XP_011272094.1 - 6.5e-40 137.2 6.0 6.5e-40 137.2 4.1 3.1 2 1 1 3 3 3 2 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 XP_011272094.1 - 7.4e-13 48.5 11.6 7.4e-13 48.5 8.0 2.5 2 0 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.3 XP_011272094.1 - 2.6e-07 29.6 6.8 2.3e-05 23.2 2.0 2.4 2 0 0 2 2 2 2 Aluminium activated malate transporter DUF2421 PF10334.4 XP_011272094.1 - 3.2e-06 26.9 0.1 8.1e-06 25.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) CIMR PF00878.13 XP_011272095.1 - 1.6e-14 53.8 0.2 9.6e-06 25.4 0.0 2.9 2 1 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat PRKCSH_1 PF13015.1 XP_011272095.1 - 0.00011 21.6 0.0 0.00021 20.8 0.0 1.4 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein DIL PF01843.14 XP_011272097.1 - 6e-14 51.7 2.5 3.4e-10 39.7 0.0 2.9 3 0 0 3 3 3 2 DIL domain Ank_2 PF12796.2 XP_011272097.1 - 4.3e-11 42.9 0.1 8.7e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 XP_011272097.1 - 1.3e-07 31.0 0.0 1.2e-06 27.9 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 XP_011272097.1 - 2.6e-07 30.6 0.0 7.1e-06 26.1 0.0 3.2 2 1 2 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 XP_011272097.1 - 0.00023 21.1 0.2 0.0032 17.5 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 XP_011272097.1 - 0.026 15.0 0.0 0.11 12.9 0.0 2.2 1 1 0 1 1 1 0 Ankyrin repeats (many copies) IncA PF04156.9 XP_011272097.1 - 0.032 13.8 3.0 0.068 12.7 2.1 1.5 1 0 0 1 1 1 0 IncA protein DUF1510 PF07423.6 XP_011272097.1 - 0.16 11.2 12.4 0.35 10.1 8.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Pho88 PF10032.4 XP_011272098.1 - 1.8e-82 275.2 1.7 2e-82 275.0 1.2 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) Cytochrom_C_asm PF01578.15 XP_011272098.1 - 0.026 14.0 3.1 0.31 10.5 0.1 2.1 2 0 0 2 2 2 0 Cytochrome C assembly protein Striatin PF08232.7 XP_011272099.1 - 2.6e-16 60.1 5.6 2.6e-16 60.1 3.9 2.9 2 2 0 2 2 2 1 Striatin family WD40 PF00400.27 XP_011272099.1 - 8.4e-09 34.9 2.3 0.0029 17.4 0.3 3.8 3 0 0 3 3 3 3 WD domain, G-beta repeat CENP-F_leu_zip PF10473.4 XP_011272099.1 - 0.0034 17.2 3.9 0.0064 16.3 2.7 1.3 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF972 PF06156.8 XP_011272099.1 - 0.015 15.6 3.3 0.038 14.3 2.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Myosin_tail_1 PF01576.14 XP_011272099.1 - 0.024 12.3 4.0 0.032 11.9 2.8 1.1 1 0 0 1 1 1 0 Myosin tail HALZ PF02183.13 XP_011272099.1 - 0.031 13.9 4.7 0.065 12.9 0.6 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper DivIC PF04977.10 XP_011272099.1 - 0.045 13.2 3.5 0.029 13.8 0.9 1.8 2 0 0 2 2 2 0 Septum formation initiator bZIP_2 PF07716.10 XP_011272099.1 - 0.091 12.6 0.5 0.2 11.4 0.4 1.6 1 0 0 1 1 1 0 Basic region leucine zipper Ax_dynein_light PF10211.4 XP_011272099.1 - 0.11 12.3 5.1 0.19 11.5 3.5 1.3 1 0 0 1 1 1 0 Axonemal dynein light chain TMF_TATA_bd PF12325.3 XP_011272099.1 - 0.12 12.0 2.9 0.27 10.9 2.0 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding IncA PF04156.9 XP_011272099.1 - 0.16 11.5 3.0 0.29 10.7 2.0 1.5 1 1 0 1 1 1 0 IncA protein bZIP_1 PF00170.16 XP_011272099.1 - 0.41 10.6 4.7 0.096 12.6 0.8 1.8 2 0 0 2 2 1 0 bZIP transcription factor DUF4482 PF14818.1 XP_011272099.1 - 0.65 10.6 9.1 0.057 14.0 2.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) Copper-fist PF00649.13 XP_011272100.1 - 2.2e-15 55.5 0.6 4.3e-15 54.6 0.4 1.5 1 0 0 1 1 1 1 Copper fist DNA binding domain UQ_con PF00179.21 XP_011272101.1 - 7.2e-41 138.8 0.0 5.6e-40 136.0 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 XP_011272101.1 - 0.024 14.3 0.0 0.044 13.5 0.0 1.5 1 1 0 1 1 1 0 Prokaryotic E2 family B CLU PF13236.1 XP_011272102.1 - 1.6e-68 230.4 0.0 1.6e-68 230.4 0.0 2.0 2 0 0 2 2 2 1 Clustered mitochondria eIF3_p135 PF12807.2 XP_011272102.1 - 5e-40 137.2 3.7 4.6e-28 98.2 0.0 3.6 3 0 0 3 3 3 2 Translation initiation factor eIF3 subunit 135 CLU_N PF15044.1 XP_011272102.1 - 4.2e-12 46.0 0.3 1.1e-11 44.6 0.2 1.8 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_12 PF13424.1 XP_011272102.1 - 3.3e-09 36.5 4.9 7.8e-06 25.7 0.4 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 XP_011272102.1 - 8.1e-05 22.4 0.7 0.0067 16.3 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 XP_011272102.1 - 0.026 14.1 0.4 0.12 12.0 0.1 2.2 2 0 0 2 2 2 0 TPR repeat CENP-B_dimeris PF09026.5 XP_011272102.1 - 1.4 9.2 8.9 0.71 10.1 0.7 2.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain SNase PF00565.12 XP_011272103.1 - 6.1e-36 122.9 1.3 2e-11 44.0 0.0 3.7 4 1 0 4 4 4 3 Staphylococcal nuclease homologue DUF2762 PF10960.3 XP_011272103.1 - 0.087 12.5 4.0 0.25 11.0 2.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2762) HEAT PF02985.17 XP_011272104.1 - 4.2e-40 132.2 7.6 0.012 15.6 0.0 13.4 14 0 0 14 14 14 11 HEAT repeat HEAT_2 PF13646.1 XP_011272104.1 - 1.8e-30 105.0 0.1 6.2e-05 23.2 0.0 7.8 2 1 6 8 8 8 8 HEAT repeats Vac14_Fab1_bd PF12755.2 XP_011272104.1 - 2.3e-11 43.9 3.6 0.0022 18.3 0.0 7.0 4 1 4 9 9 9 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 XP_011272104.1 - 1.9e-09 37.7 5.1 0.47 11.0 0.0 9.4 8 4 3 11 11 11 2 HEAT-like repeat RIX1 PF08167.7 XP_011272104.1 - 4.3e-05 23.2 0.5 1.7 8.2 0.0 4.3 4 0 0 4 4 4 2 rRNA processing/ribosome biogenesis DUF1546 PF07571.8 XP_011272104.1 - 0.017 15.2 0.3 4.7 7.3 0.0 4.2 3 2 2 5 5 5 0 Protein of unknown function (DUF1546) Y_phosphatase3 PF13350.1 XP_011272105.1 - 0.96 9.6 3.8 3.3 7.9 1.3 2.5 2 0 0 2 2 2 0 Tyrosine phosphatase family AA_permease_2 PF13520.1 XP_011272106.1 - 7.3e-70 235.6 38.7 9.2e-70 235.3 26.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 XP_011272106.1 - 1.3e-17 63.3 31.0 2.4e-17 62.4 21.5 1.4 1 1 0 1 1 1 1 Amino acid permease MFS_1 PF07690.11 XP_011272107.1 - 6.9e-23 80.9 39.9 3.6e-15 55.5 19.9 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 XP_011272107.1 - 1e-06 27.2 24.9 0.0001 20.6 3.1 3.0 2 1 1 3 3 3 3 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 XP_011272107.1 - 9.1e-06 24.0 0.7 1.5e-05 23.3 0.5 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector DUF2999 PF11212.3 XP_011272107.1 - 0.012 15.6 0.0 1.6 8.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2999) MFS_1 PF07690.11 XP_011272108.1 - 5.4e-23 81.2 40.6 2e-17 62.9 16.1 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 XP_011272108.1 - 5.1e-06 24.8 0.2 1.1e-05 23.7 0.2 1.5 1 0 0 1 1 1 1 Transmembrane secretion effector DUF2999 PF11212.3 XP_011272108.1 - 0.062 13.3 0.0 11 6.1 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2999) S1FA PF04689.8 XP_011272108.1 - 0.11 12.4 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 DNA binding protein S1FA MFS_1 PF07690.11 XP_011272109.1 - 3.6e-23 81.8 40.1 9.8e-15 54.1 16.6 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_3 PF05977.8 XP_011272109.1 - 9.5e-06 23.9 1.7 1.8e-05 23.1 1.2 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector TRI12 PF06609.8 XP_011272109.1 - 0.002 16.4 33.2 2.8 6.0 23.0 2.9 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) UPF0197 PF05251.7 XP_011272109.1 - 5.8 7.2 13.0 12 6.2 1.0 4.4 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0197) MFS_1 PF07690.11 XP_011272110.1 - 2.7e-22 78.9 42.8 2.7e-15 55.9 20.7 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 XP_011272110.1 - 0.00065 18.0 6.1 0.00065 18.0 4.2 3.0 2 1 0 3 3 3 2 Fungal trichothecene efflux pump (TRI12) Cofilin_ADF PF00241.15 XP_011272111.1 - 3e-26 91.7 9.2 1.6e-14 53.8 1.5 2.7 2 1 1 3 3 3 2 Cofilin/tropomyosin-type actin-binding protein zf-RING_2 PF13639.1 XP_011272112.1 - 5e-14 51.8 21.2 1.1e-12 47.5 3.7 2.5 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_3 PF13920.1 XP_011272112.1 - 1.1e-08 34.6 14.6 4e-07 29.6 1.2 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 XP_011272112.1 - 1.7e-08 34.4 16.4 1.5e-07 31.4 3.2 2.5 2 0 0 2 2 2 2 RING-H2 zinc finger zf-C3HC4 PF00097.20 XP_011272112.1 - 6.1e-06 25.7 6.3 6.1e-06 25.7 4.4 3.0 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 XP_011272112.1 - 8e-06 25.4 18.3 0.00012 21.7 4.3 2.5 2 0 0 2 2 2 2 PHD-finger zf-RING_5 PF14634.1 XP_011272112.1 - 1.1e-05 24.9 4.7 1.1e-05 24.9 3.3 3.0 2 1 1 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 XP_011272112.1 - 1.9e-05 24.5 5.6 1.9e-05 24.5 3.9 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-HC5HC2H PF13771.1 XP_011272112.1 - 0.0017 18.4 1.4 0.0017 18.4 1.0 3.0 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-Apc11 PF12861.2 XP_011272112.1 - 0.0028 17.4 9.3 0.0037 17.0 0.9 2.9 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-HC5HC2H_2 PF13832.1 XP_011272112.1 - 0.0035 17.3 2.8 0.0035 17.3 2.0 2.9 1 1 0 2 2 2 1 PHD-zinc-finger like domain zf-RING_UBOX PF13445.1 XP_011272112.1 - 0.089 12.5 2.5 0.54 10.0 1.7 2.5 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_1 PF14446.1 XP_011272112.1 - 0.56 9.9 17.9 3.8 7.3 3.1 3.5 2 2 1 3 3 3 0 Prokaryotic RING finger family 1 PHD_2 PF13831.1 XP_011272112.1 - 7.2 6.0 13.4 0.035 13.4 2.0 2.3 2 0 0 2 2 2 0 PHD-finger zf-PHD-like PF15446.1 XP_011272112.1 - 9.7 5.4 16.0 1.3 8.3 2.6 3.1 3 0 0 3 3 3 0 PHD/FYVE-zinc-finger like domain PHF5 PF03660.9 XP_011272113.1 - 1.4e-51 173.0 12.6 1.6e-51 172.8 8.8 1.0 1 0 0 1 1 1 1 PHF5-like protein DZR PF12773.2 XP_011272113.1 - 0.62 9.9 15.0 0.5 10.2 5.3 2.8 1 1 2 3 3 3 0 Double zinc ribbon Sec7 PF01369.15 XP_011272114.1 - 1.9e-39 135.3 0.3 1.9e-39 135.3 0.2 1.9 2 0 0 2 2 2 1 Sec7 domain PH_9 PF15410.1 XP_011272114.1 - 0.019 15.0 0.0 0.065 13.3 0.0 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain PBP PF01161.15 XP_011272115.1 - 3.2e-16 59.4 0.1 4.2e-16 59.1 0.1 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein CENP-B_dimeris PF09026.5 XP_011272116.1 - 0.0031 17.7 9.8 0.0031 17.7 6.8 4.2 2 1 2 4 4 4 2 Centromere protein B dimerisation domain DUF3633 PF12315.3 XP_011272116.1 - 0.1 11.9 0.2 0.23 10.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3633) DUF947 PF06102.7 XP_011272116.1 - 2.9 7.6 12.6 8.4 6.1 5.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF947) MFS_1 PF07690.11 XP_011272117.1 - 2.8e-52 177.6 24.9 6.6e-52 176.3 17.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily ESSS PF10183.4 XP_011272117.1 - 0.0012 19.1 0.0 0.0041 17.4 0.0 2.0 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Bax1-I PF01027.15 XP_011272117.1 - 1 8.9 32.7 0.083 12.4 7.5 2.6 2 1 0 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 MFS_1 PF07690.11 XP_011272118.1 - 4.8e-50 170.2 21.0 5.7e-50 169.9 14.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily ESSS PF10183.4 XP_011272118.1 - 0.12 12.7 0.5 0.32 11.4 0.1 1.8 1 1 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Peptidase_M20 PF01546.23 XP_011272119.1 - 9.7e-21 74.1 0.0 1.5e-20 73.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 XP_011272119.1 - 3.7e-09 36.2 0.0 9.1e-09 35.0 0.0 1.7 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 XP_011272120.1 - 1.8e-23 83.0 0.0 2.8e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 XP_011272120.1 - 5.1e-11 42.2 0.0 1.7e-10 40.6 0.0 1.8 1 1 0 1 1 1 1 Peptidase dimerisation domain Proteasome PF00227.21 XP_011272121.1 - 2.9e-38 131.0 0.1 2.8e-37 127.8 0.1 1.9 1 1 0 1 1 1 1 Proteasome subunit POLO_box PF00659.13 XP_011272121.1 - 0.036 14.0 0.1 0.095 12.6 0.0 1.7 1 0 0 1 1 1 0 POLO box duplicated region Vps51 PF08700.6 XP_011272122.1 - 3.2e-06 26.8 2.2 3.2e-06 26.8 1.5 2.7 2 1 1 3 3 3 1 Vps51/Vps67 SR-25 PF10500.4 XP_011272122.1 - 0.0036 16.8 5.8 0.0063 16.0 4.0 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Lumazine_bd PF12870.2 XP_011272122.1 - 1.9 8.5 8.4 0.67 10.0 2.6 2.5 1 1 1 3 3 3 0 Lumazine-binding domain PI-PLC-X PF00388.14 XP_011272123.1 - 5.8e-51 171.7 0.0 1.8e-50 170.1 0.0 1.9 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 XP_011272123.1 - 1.6e-40 137.7 1.1 4.7e-40 136.2 0.7 1.9 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 XP_011272123.1 - 3.3e-06 27.0 2.4 5.4e-06 26.3 0.1 2.5 3 0 0 3 3 3 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_8 PF13833.1 XP_011272123.1 - 0.00017 21.1 0.3 0.00051 19.6 0.2 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_10 PF14788.1 XP_011272123.1 - 0.00038 20.0 0.4 0.00038 20.0 0.3 2.2 2 0 0 2 2 2 1 EF hand C2 PF00168.25 XP_011272123.1 - 0.0016 18.2 0.1 0.0065 16.2 0.0 2.1 2 0 0 2 2 2 1 C2 domain EF-hand_1 PF00036.27 XP_011272123.1 - 0.0018 17.4 0.1 0.0052 15.9 0.1 1.9 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 XP_011272123.1 - 0.0038 17.3 3.2 0.024 14.7 1.6 2.7 1 1 0 1 1 1 1 EF-hand domain pair DUF2794 PF10984.3 XP_011272123.1 - 0.082 12.7 0.0 22 4.9 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2794) EF-hand_6 PF13405.1 XP_011272123.1 - 0.082 12.8 2.3 0.28 11.1 0.1 2.6 2 0 0 2 2 2 0 EF-hand domain Bystin PF05291.6 XP_011272124.1 - 5e-123 409.8 0.6 7.6e-123 409.2 0.4 1.2 1 0 0 1 1 1 1 Bystin GFO_IDH_MocA PF01408.17 XP_011272125.1 - 2e-21 76.7 0.0 3.8e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 XP_011272125.1 - 1e-05 25.9 0.1 1.8e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 XP_011272125.1 - 0.0019 18.4 0.1 0.0038 17.5 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.12 XP_011272125.1 - 0.023 15.1 0.0 0.12 12.8 0.0 2.2 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DUF2334 PF10096.4 XP_011272125.1 - 0.029 13.7 0.5 0.094 12.1 0.1 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2334) RCC1 PF00415.13 XP_011272126.1 - 4.7e-68 225.2 0.1 4.9e-14 52.2 0.0 7.4 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 XP_011272126.1 - 6.8e-42 140.2 16.3 5e-10 38.7 0.0 6.4 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat His_biosynth PF00977.16 XP_011272127.1 - 4.5e-43 147.1 0.7 2.8e-42 144.5 0.3 2.5 2 1 0 2 2 2 1 Histidine biosynthesis protein GATase PF00117.23 XP_011272127.1 - 1.2e-27 96.6 0.0 2e-27 95.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.14 XP_011272127.1 - 2.4e-06 27.2 0.0 3.1e-05 23.7 0.0 2.1 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.9 XP_011272127.1 - 1.5e-05 24.6 0.0 5.8e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_S51 PF03575.12 XP_011272127.1 - 0.04 13.6 0.0 0.077 12.7 0.0 1.4 1 0 0 1 1 1 0 Peptidase family S51 Peptidase_C26 PF07722.8 XP_011272127.1 - 0.047 13.1 0.0 0.22 10.9 0.0 2.0 1 1 0 1 1 1 0 Peptidase C26 DAHP_synth_1 PF00793.15 XP_011272128.1 - 1.4e-98 328.9 0.1 1.8e-98 328.5 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Cyclin PF08613.6 XP_011272129.1 - 4.1e-32 111.6 0.9 4.1e-32 111.6 0.6 2.4 3 0 0 3 3 3 1 Cyclin DUF4615 PF15393.1 XP_011272129.1 - 0.02 15.1 3.0 0.056 13.6 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4615) Cyclin_N PF00134.18 XP_011272129.1 - 0.02 14.4 0.0 0.045 13.3 0.0 1.6 1 0 0 1 1 1 0 Cyclin, N-terminal domain Striatin PF08232.7 XP_011272129.1 - 0.53 10.5 6.9 1 9.6 1.0 2.3 2 0 0 2 2 2 0 Striatin family DUF4512 PF14975.1 XP_011272129.1 - 1.7 9.4 5.7 18 6.2 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4512) APC_CDC26 PF10471.4 XP_011272129.1 - 4.5 8.0 18.4 0.78 10.5 1.0 2.7 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit 1 Ras PF00071.17 XP_011272130.1 - 4.6e-57 191.9 1.0 5.7e-57 191.6 0.7 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 XP_011272130.1 - 8.7e-21 74.6 0.1 1.3e-20 74.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 XP_011272130.1 - 4.5e-15 55.3 0.3 5.3e-15 55.0 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 XP_011272130.1 - 2e-07 30.6 0.5 3.4e-06 26.6 0.3 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 XP_011272130.1 - 5.4e-07 28.9 0.3 6.4e-07 28.7 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 XP_011272130.1 - 2.6e-06 27.3 0.0 4.5e-06 26.6 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 XP_011272130.1 - 9.3e-05 21.7 0.2 0.00013 21.2 0.2 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.12 XP_011272130.1 - 9.8e-05 22.0 1.3 0.0061 16.1 0.1 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein PduV-EutP PF10662.4 XP_011272130.1 - 0.00013 21.4 1.9 0.0055 16.1 1.3 2.4 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 XP_011272130.1 - 0.0014 18.7 0.1 0.0033 17.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 XP_011272130.1 - 0.0018 18.0 0.6 0.004 16.8 0.4 1.8 1 1 0 1 1 1 1 Archaeal ATPase AAA_24 PF13479.1 XP_011272130.1 - 0.0022 17.6 0.7 0.0049 16.4 0.1 1.8 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 XP_011272130.1 - 0.0029 17.2 0.0 0.0048 16.5 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 XP_011272130.1 - 0.0032 17.4 0.1 0.033 14.1 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 XP_011272130.1 - 0.01 15.0 0.0 0.016 14.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Septin PF00735.13 XP_011272130.1 - 0.013 14.5 1.3 0.072 12.0 0.1 2.2 2 1 0 2 2 2 0 Septin MobB PF03205.9 XP_011272130.1 - 0.014 15.0 0.1 0.03 14.0 0.0 1.7 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 XP_011272130.1 - 0.019 14.3 0.5 0.11 11.8 0.0 2.0 1 1 2 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain PRK PF00485.13 XP_011272130.1 - 0.044 13.3 0.0 0.086 12.3 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_10 PF12846.2 XP_011272130.1 - 0.048 13.0 0.2 0.13 11.7 0.1 1.6 2 0 0 2 2 2 0 AAA-like domain AAA_5 PF07728.9 XP_011272130.1 - 0.074 12.7 0.1 0.27 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.17 XP_011272130.1 - 0.095 11.5 0.6 0.16 10.7 0.3 1.6 1 1 0 1 1 1 0 NB-ARC domain NTPase_1 PF03266.10 XP_011272130.1 - 0.1 12.2 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_14 PF13173.1 XP_011272130.1 - 0.12 12.3 0.6 0.26 11.1 0.1 2.0 1 1 1 2 2 2 0 AAA domain AAA_23 PF13476.1 XP_011272130.1 - 0.13 12.5 6.3 0.25 11.6 4.4 1.5 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.15 XP_011272130.1 - 0.69 8.5 6.7 5 5.7 4.6 2.6 1 1 0 1 1 1 0 G-protein alpha subunit ABC_tran PF00005.22 XP_011272130.1 - 0.76 10.0 5.1 2.3 8.5 3.6 1.9 1 1 0 1 1 1 0 ABC transporter Ribul_P_3_epim PF00834.14 XP_011272131.1 - 3.7e-70 235.1 0.0 4.5e-70 234.8 0.0 1.1 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family OMPdecase PF00215.19 XP_011272131.1 - 0.0072 15.7 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family ThiG PF05690.9 XP_011272131.1 - 0.011 14.8 0.3 0.016 14.3 0.2 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG PcrB PF01884.12 XP_011272131.1 - 0.032 13.4 0.0 0.045 12.9 0.0 1.2 1 0 0 1 1 1 0 PcrB family PG_binding_3 PF09374.5 XP_011272131.1 - 0.051 13.5 0.1 0.095 12.6 0.0 1.4 1 0 0 1 1 1 0 Predicted Peptidoglycan domain QRPTase_C PF01729.14 XP_011272131.1 - 0.1 12.1 0.0 0.38 10.2 0.0 1.8 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain Alb1 PF09135.6 XP_011272132.1 - 4.7e-10 40.0 12.1 4.7e-10 40.0 8.4 1.9 1 1 1 2 2 2 1 Alb1 PBP1_TM PF14812.1 XP_011272132.1 - 1 9.7 5.8 0.16 12.3 0.6 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-RING_2 PF13639.1 XP_011272133.1 - 1e-10 41.2 6.2 1.9e-10 40.4 4.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 XP_011272133.1 - 4.7e-07 29.4 3.9 9.6e-07 28.4 2.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 XP_011272133.1 - 5e-06 26.4 5.4 1.1e-05 25.3 3.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 XP_011272133.1 - 0.0001 21.8 4.0 0.00021 20.9 2.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 XP_011272133.1 - 0.00019 21.0 3.7 0.00049 19.7 2.6 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.20 XP_011272133.1 - 0.00033 20.2 5.4 0.00072 19.1 3.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.1 XP_011272133.1 - 0.0007 19.2 2.2 0.0017 18.0 0.2 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 FANCL_C PF11793.3 XP_011272133.1 - 0.0012 18.7 2.8 0.0033 17.3 2.0 1.7 1 1 0 1 1 1 1 FANCL C-terminal domain zf-rbx1 PF12678.2 XP_011272133.1 - 0.0098 15.9 3.8 0.024 14.7 2.6 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger Podoplanin PF05808.6 XP_011272133.1 - 0.022 14.2 0.1 0.043 13.3 0.0 1.4 1 0 0 1 1 1 0 Podoplanin PHD PF00628.24 XP_011272133.1 - 0.023 14.4 1.4 0.054 13.1 0.9 1.7 1 1 0 1 1 1 0 PHD-finger zf-RING_4 PF14570.1 XP_011272133.1 - 0.049 13.2 1.4 0.12 12.0 1.0 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 XP_011272133.1 - 0.12 12.2 4.6 0.29 11.0 3.2 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF912 PF06024.7 XP_011272133.1 - 0.21 11.6 1.1 0.71 9.9 0.1 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Tetraspannin PF00335.15 XP_011272133.1 - 0.69 9.1 9.0 2 7.6 6.2 1.8 1 1 0 1 1 1 0 Tetraspanin family DUF3139 PF11337.3 XP_011272133.1 - 1.7 8.9 7.2 0.13 12.5 0.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3139) zf-Nse PF11789.3 XP_011272133.1 - 7.5 6.1 7.6 15 5.1 3.9 2.5 2 1 1 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit Zn_clus PF00172.13 XP_011272135.1 - 1.7e-05 24.6 7.9 3.3e-05 23.6 5.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Alk_phosphatase PF00245.15 XP_011272136.1 - 2.6e-86 289.9 0.1 3.1e-86 289.6 0.1 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 XP_011272136.1 - 0.00018 21.0 1.4 0.0026 17.2 0.7 2.6 2 1 0 2 2 2 1 Metalloenzyme superfamily Bet_v_1 PF00407.14 XP_011272137.1 - 0.072 12.7 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Pathogenesis-related protein Bet v I family F-box-like PF12937.2 XP_011272137.1 - 0.11 12.1 0.3 0.36 10.5 0.1 2.0 2 0 0 2 2 2 0 F-box-like dCMP_cyt_deam_1 PF00383.17 XP_011272138.1 - 1.7e-23 82.2 0.0 2.1e-23 81.8 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 XP_011272138.1 - 0.0032 17.3 0.9 0.063 13.1 0.3 2.1 1 1 1 2 2 2 1 Bd3614-like deaminase APOBEC_N PF08210.6 XP_011272138.1 - 0.046 13.3 0.0 0.069 12.7 0.0 1.3 1 0 0 1 1 1 0 APOBEC-like N-terminal domain UPF0139 PF03669.8 XP_011272139.1 - 0.0095 15.4 0.2 0.013 15.0 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) EST1_DNA_bind PF10373.4 XP_011272140.1 - 0.003 16.7 0.3 0.0038 16.4 0.2 1.0 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain CD34_antigen PF06365.7 XP_011272140.1 - 0.065 12.8 0.0 0.093 12.3 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family DUF912 PF06024.7 XP_011272140.1 - 0.17 11.9 1.0 0.25 11.4 0.6 1.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) zf-RING_2 PF13639.1 XP_011272141.1 - 8.2e-10 38.3 6.5 1.2e-09 37.8 4.5 1.2 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 XP_011272141.1 - 1.5e-06 27.8 4.5 2.4e-06 27.1 3.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 XP_011272141.1 - 2.1e-05 24.4 5.5 4.3e-05 23.4 3.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 XP_011272141.1 - 8.7e-05 22.1 4.2 0.00015 21.3 2.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 XP_011272141.1 - 0.0002 20.9 6.0 0.00038 20.0 4.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 XP_011272141.1 - 0.00029 20.4 3.6 0.00059 19.4 2.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_1 PF14446.1 XP_011272141.1 - 0.00081 19.0 0.6 0.00081 19.0 0.4 2.1 1 1 0 2 2 2 1 Prokaryotic RING finger family 1 FANCL_C PF11793.3 XP_011272141.1 - 0.001 18.9 3.1 0.0023 17.8 2.1 1.6 1 1 0 1 1 1 1 FANCL C-terminal domain PHD PF00628.24 XP_011272141.1 - 0.013 15.1 2.9 0.028 14.0 2.0 1.6 1 1 0 1 1 1 0 PHD-finger zf-rbx1 PF12678.2 XP_011272141.1 - 0.036 14.1 5.6 0.082 13.0 3.9 1.6 1 1 0 1 1 1 0 RING-H2 zinc finger MRP-S25 PF13741.1 XP_011272141.1 - 0.065 12.6 1.9 0.091 12.2 1.3 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein S25 zf-RING_4 PF14570.1 XP_011272141.1 - 0.065 12.8 2.1 0.15 11.6 1.5 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 XP_011272141.1 - 0.63 9.9 3.2 2 8.3 2.2 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Exo_endo_phos_2 PF14529.1 XP_011272142.1 - 0.0067 16.0 0.1 0.035 13.7 0.0 2.2 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Voldacs PF03517.8 XP_011272143.1 - 0.013 15.3 3.1 0.017 14.9 2.0 1.5 1 1 0 1 1 1 0 Regulator of volume decrease after cellular swelling FAM150 PF15129.1 XP_011272144.1 - 0.0049 16.7 0.2 0.015 15.1 0.1 1.8 1 0 0 1 1 1 1 FAM150 family ATG11 PF10377.4 XP_011272145.1 - 7e-20 71.2 2.0 7e-20 71.2 1.4 4.2 4 0 0 4 4 4 1 Autophagy-related protein 11 DUF1843 PF08898.5 XP_011272145.1 - 0.021 14.8 9.8 1.2 9.2 0.4 4.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) Acetyltransf_1 PF00583.19 XP_011272146.1 - 2.1e-17 62.9 0.0 3.3e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 XP_011272146.1 - 3.4e-10 39.5 0.1 5.7e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 XP_011272146.1 - 1.3e-08 34.8 0.0 2e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 XP_011272146.1 - 6.5e-08 32.7 0.0 9e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 XP_011272146.1 - 2.7e-07 30.5 0.0 3.7e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 XP_011272146.1 - 9.1e-07 29.1 0.0 1.1e-06 28.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 XP_011272146.1 - 1.2e-05 25.1 0.0 1.9e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 XP_011272146.1 - 0.0003 20.5 0.0 0.00053 19.8 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.1 XP_011272146.1 - 0.0011 18.9 0.1 0.0021 18.0 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain PCNA_C PF02747.10 XP_011272147.1 - 5.7e-46 155.5 0.1 1.2e-45 154.5 0.1 1.5 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.13 XP_011272147.1 - 3.6e-42 142.8 3.2 1.2e-41 141.2 1.1 2.2 2 1 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain Rad9 PF04139.8 XP_011272147.1 - 5.2e-05 22.4 0.3 6.6e-05 22.1 0.2 1.1 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.7 XP_011272147.1 - 0.00023 20.2 0.1 0.2 10.5 0.0 2.2 2 0 0 2 2 2 2 Hus1-like protein Rad1 PF02144.11 XP_011272147.1 - 0.00039 19.2 0.2 0.036 12.8 0.2 2.1 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 RXT2_N PF08595.6 XP_011272148.1 - 9.2e-37 126.1 5.5 9.2e-37 126.1 3.8 2.5 3 0 0 3 3 3 1 RXT2-like, N-terminal TTL PF03133.10 XP_011272149.1 - 2.4e-64 217.0 1.7 3.6e-64 216.5 1.2 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.12 XP_011272149.1 - 1.3e-42 145.3 0.0 2e-42 144.7 0.0 1.3 1 0 0 1 1 1 1 Survival protein SurE Nro1 PF12753.2 XP_011272149.1 - 5.5e-05 22.2 1.6 0.00012 21.1 1.1 1.5 1 0 0 1 1 1 1 Nuclear pore complex subunit Nro1 ATP-grasp_4 PF13535.1 XP_011272149.1 - 0.00028 20.6 0.1 0.00086 19.0 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_YheCD PF14398.1 XP_011272149.1 - 0.0005 18.9 0.1 0.057 12.2 0.0 2.7 2 1 1 3 3 3 1 YheC/D like ATP-grasp HMG_box PF00505.14 XP_011272150.1 - 7.8e-22 77.3 0.2 1.1e-21 76.8 0.1 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 XP_011272150.1 - 2.9e-16 59.5 0.5 3.7e-16 59.2 0.4 1.2 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 XP_011272150.1 - 0.028 14.2 1.4 0.028 14.2 1.0 1.5 2 0 0 2 2 2 0 HMG (high mobility group) box 5 ERCC4 PF02732.10 XP_011272151.1 - 2.4e-09 37.0 1.7 2.4e-09 37.0 1.2 1.9 2 0 0 2 2 2 1 ERCC4 domain Fes1 PF08609.5 XP_011272152.1 - 2.7e-21 75.8 4.6 2.7e-21 75.8 3.2 2.7 3 0 0 3 3 3 1 Nucleotide exchange factor Fes1 NAD_binding_7 PF13241.1 XP_011272152.1 - 0.04 14.1 0.0 0.14 12.3 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding FPL PF09758.4 XP_011272152.1 - 0.066 12.9 14.2 0.66 9.7 0.4 3.2 1 1 2 3 3 3 0 Uncharacterised conserved protein GrpE PF01025.14 XP_011272152.1 - 0.38 10.2 4.1 0.48 9.9 0.8 2.5 2 1 0 2 2 2 0 GrpE Vps51 PF08700.6 XP_011272153.1 - 5.1e-05 23.0 3.4 0.00028 20.6 2.4 2.4 1 0 0 1 1 1 1 Vps51/Vps67 WD40 PF00400.27 XP_011272154.1 - 4e-27 93.0 15.1 2.6e-09 36.5 0.1 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat LisH PF08513.6 XP_011272154.1 - 6e-09 35.3 0.1 1.3e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 LisH eIF2A PF08662.6 XP_011272154.1 - 2.5e-05 24.0 0.2 0.035 13.7 0.0 3.9 2 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 XP_011272154.1 - 0.0057 14.8 1.5 0.13 10.3 0.0 2.8 2 1 1 3 3 3 1 Nucleoporin Nup120/160 Apc4_WD40 PF12894.2 XP_011272154.1 - 0.014 14.8 0.0 0.1 12.1 0.0 2.5 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.1 XP_011272154.1 - 0.023 13.7 0.0 0.21 10.5 0.0 2.1 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Tfb4 PF03850.9 XP_011272155.1 - 1.7e-91 306.3 2.3 2.5e-91 305.7 1.6 1.2 1 0 0 1 1 1 1 Transcription factor Tfb4 Hom_end_hint PF05203.11 XP_011272155.1 - 0.0051 16.5 0.1 0.0064 16.2 0.1 1.2 1 0 0 1 1 1 1 Hom_end-associated Hint SIP1 PF04938.7 XP_011272156.1 - 5.4e-11 42.2 0.6 5.4e-11 42.2 0.4 2.1 2 1 0 2 2 2 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) DAO PF01266.19 XP_011272157.1 - 2.6e-26 92.4 0.0 5.6e-26 91.2 0.0 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 XP_011272157.1 - 0.0014 19.0 0.6 0.0031 17.8 0.4 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 XP_011272157.1 - 0.0028 17.5 0.0 0.0043 16.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 XP_011272157.1 - 0.0047 17.0 0.1 0.028 14.5 0.1 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 XP_011272157.1 - 0.0061 16.0 0.2 0.012 15.0 0.2 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_8 PF13450.1 XP_011272157.1 - 0.015 15.3 0.1 0.043 13.8 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.13 XP_011272157.1 - 0.041 13.5 0.1 0.065 12.8 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 XP_011272157.1 - 0.059 13.6 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding FAD_binding_2 PF00890.19 XP_011272157.1 - 0.079 11.7 0.1 0.11 11.2 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.14 XP_011272157.1 - 0.17 10.9 0.6 0.27 10.2 0.4 1.2 1 0 0 1 1 1 0 FAD binding domain Rep_fac_C PF08542.6 XP_011272158.1 - 3.7e-18 65.3 0.1 1.4e-17 63.4 0.0 2.0 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 XP_011272158.1 - 6.1e-12 45.4 0.1 1e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 XP_011272158.1 - 2.8e-07 30.7 0.1 6.1e-07 29.6 0.1 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 XP_011272158.1 - 1.1e-06 28.8 3.1 7e-05 22.9 0.2 3.1 1 1 2 3 3 3 1 AAA domain Sigma54_activ_2 PF14532.1 XP_011272158.1 - 0.0014 18.6 0.4 0.0064 16.5 0.3 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_10 PF12846.2 XP_011272158.1 - 0.0077 15.7 0.3 0.017 14.5 0.2 1.7 1 1 0 1 1 1 1 AAA-like domain AAA_16 PF13191.1 XP_011272158.1 - 0.014 15.3 1.4 0.27 11.1 0.1 2.6 2 1 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.1 XP_011272158.1 - 0.027 14.0 0.1 0.052 13.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain Guanylate_kin PF00625.16 XP_011272158.1 - 0.11 11.9 1.5 1.5 8.1 0.0 2.8 2 1 0 2 2 2 0 Guanylate kinase Resolvase PF00239.16 XP_011272158.1 - 0.14 12.0 1.9 0.51 10.2 1.0 2.1 1 1 1 2 2 2 0 Resolvase, N terminal domain Ribosomal_L16 PF00252.13 XP_011272159.1 - 3.1e-34 117.5 0.9 4.4e-34 117.1 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e tRNA-synt_2d PF01409.15 XP_011272160.1 - 4.8e-53 179.8 1.1 4.4e-26 91.5 0.0 2.6 1 1 2 3 3 3 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 XP_011272160.1 - 2.2e-24 85.4 0.0 4.3e-24 84.5 0.0 1.5 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain tRNA-synt_2 PF00152.15 XP_011272160.1 - 0.0015 17.4 0.9 0.17 10.6 0.1 3.0 3 0 0 3 3 3 2 tRNA synthetases class II (D, K and N) GrpE PF01025.14 XP_011272161.1 - 8.3e-46 155.5 6.5 1.1e-45 155.1 4.5 1.2 1 0 0 1 1 1 1 GrpE SH3BP5 PF05276.9 XP_011272161.1 - 0.0029 16.9 3.7 0.004 16.5 2.6 1.2 1 0 0 1 1 1 1 SH3 domain-binding protein 5 (SH3BP5) DUF4446 PF14584.1 XP_011272161.1 - 0.015 15.1 4.6 0.37 10.5 0.0 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF4446) DUF2935 PF11155.3 XP_011272161.1 - 0.025 14.6 3.1 2.2 8.3 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) DUF4564 PF15169.1 XP_011272161.1 - 0.072 12.8 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4564) Uds1 PF15456.1 XP_011272161.1 - 0.2 11.6 4.3 0.11 12.5 1.4 1.7 1 1 1 2 2 2 0 Up-regulated During Septation YqfQ PF14181.1 XP_011272161.1 - 0.21 11.6 1.9 0.42 10.6 1.3 1.5 1 0 0 1 1 1 0 YqfQ-like protein RmuC PF02646.11 XP_011272161.1 - 0.35 9.6 6.5 0.21 10.3 2.8 1.7 1 1 1 2 2 2 0 RmuC family TPR_MLP1_2 PF07926.7 XP_011272161.1 - 1.3 8.7 11.2 2.5 7.8 7.8 1.5 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Bap31 PF05529.7 XP_011272161.1 - 2 7.8 11.0 0.69 9.3 5.8 1.5 1 1 1 2 2 2 0 B-cell receptor-associated protein 31-like Seryl_tRNA_N PF02403.17 XP_011272161.1 - 6.9 6.7 10.0 2.2 8.3 4.3 2.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FAD_binding_1 PF00667.15 XP_011272162.1 - 1.1e-38 132.8 0.0 1.9e-38 132.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 XP_011272162.1 - 1.8e-27 96.1 0.0 3.3e-27 95.2 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 XP_011272162.1 - 1.3e-18 67.5 0.0 2.6e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_3 PF12641.2 XP_011272162.1 - 0.00037 19.9 0.0 0.26 10.6 0.0 2.3 2 0 0 2 2 2 2 Flavodoxin domain Antitoxin-MazE PF04014.13 XP_011272162.1 - 0.014 15.1 0.0 0.96 9.2 0.0 2.5 2 0 0 2 2 2 0 Antidote-toxin recognition MazE FAD_binding_6 PF00970.19 XP_011272162.1 - 0.03 14.4 0.0 0.15 12.1 0.0 2.1 2 0 0 2 2 2 0 Oxidoreductase FAD-binding domain Flavodoxin_NdrI PF07972.6 XP_011272162.1 - 0.13 12.2 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 NrdI Flavodoxin like Mannosyl_trans3 PF11051.3 XP_011272163.1 - 6e-59 199.6 0.2 6e-59 199.6 0.1 2.1 2 0 0 2 2 2 1 Mannosyltransferase putative Rxt3 PF08642.5 XP_011272163.1 - 0.0039 17.4 0.1 0.023 14.9 0.0 2.3 3 0 0 3 3 3 1 Histone deacetylation protein Rxt3 Mannosyl_trans3 PF11051.3 XP_011272164.1 - 1.7e-59 201.4 0.1 1.7e-59 201.4 0.1 2.2 2 0 0 2 2 2 1 Mannosyltransferase putative Ribosomal_S13 PF00416.17 XP_011272164.1 - 0.23 11.9 0.9 0.56 10.6 0.0 2.0 2 0 0 2 2 2 0 Ribosomal protein S13/S18 BLOC1_2 PF10046.4 XP_011272165.1 - 0.59 10.3 10.9 0.064 13.3 2.9 2.7 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Dor1 PF04124.7 XP_011272166.1 - 0.0093 14.4 0.2 0.013 13.9 0.2 1.2 1 0 0 1 1 1 1 Dor1-like family MscS_porin PF12795.2 XP_011272166.1 - 0.019 14.3 2.2 0.031 13.6 1.5 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Hemagglutinin PF00509.13 XP_011272166.1 - 0.038 12.1 1.7 0.051 11.7 1.2 1.1 1 0 0 1 1 1 0 Haemagglutinin DUF1192 PF06698.6 XP_011272166.1 - 0.056 13.2 0.9 0.28 11.0 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Osmo_CC PF08946.5 XP_011272166.1 - 0.073 13.1 0.5 0.2 11.7 0.3 1.7 1 0 0 1 1 1 0 Osmosensory transporter coiled coil ApoB100_C PF12491.3 XP_011272166.1 - 0.1 12.2 6.7 3.2 7.4 0.4 3.3 2 1 1 3 3 3 0 Apolipoprotein B100 C terminal TrmE_N PF10396.4 XP_011272168.1 - 2.4e-28 98.3 1.2 2e-26 92.1 0.3 3.0 3 1 0 3 3 2 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.18 XP_011272168.1 - 1.7e-20 73.0 3.0 3.9e-20 71.9 0.7 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 XP_011272168.1 - 2.6e-14 52.7 1.4 5e-14 51.8 1.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B GTPase_Cys_C PF12631.2 XP_011272168.1 - 4.4e-14 52.6 0.0 1.2e-13 51.2 0.0 1.8 1 0 0 1 1 1 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE Dynamin_N PF00350.18 XP_011272168.1 - 2.8e-05 23.9 4.9 0.0069 16.2 0.0 3.4 2 2 2 4 4 4 2 Dynamin family GTP_EFTU PF00009.22 XP_011272168.1 - 3.6e-05 23.2 2.9 0.00011 21.6 0.2 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Miro PF08477.8 XP_011272168.1 - 0.00021 21.7 0.2 0.00062 20.2 0.0 1.9 2 0 0 2 2 1 1 Miro-like protein Arf PF00025.16 XP_011272168.1 - 0.00057 19.1 1.6 0.0042 16.3 1.1 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family DUF258 PF03193.11 XP_011272168.1 - 0.0025 17.0 0.1 0.0053 15.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Ras PF00071.17 XP_011272168.1 - 0.011 15.1 0.0 0.074 12.4 0.0 2.2 1 1 0 1 1 1 0 Ras family Gtr1_RagA PF04670.7 XP_011272168.1 - 0.013 14.6 1.6 0.027 13.6 0.1 2.1 2 1 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_17 PF13207.1 XP_011272168.1 - 0.033 15.0 0.5 0.1 13.4 0.0 2.3 2 2 0 2 2 2 0 AAA domain cobW PF02492.14 XP_011272168.1 - 0.046 13.1 3.0 4.6 6.6 0.9 2.4 1 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 XP_011272168.1 - 0.056 13.7 2.3 0.2 11.9 0.0 2.7 1 1 1 2 2 2 0 AAA domain Hydantoinase_A PF01968.13 XP_011272168.1 - 0.079 12.0 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase CAF1-p150_N PF15557.1 XP_011272168.1 - 0.11 11.8 0.5 0.23 10.7 0.0 1.7 2 0 0 2 2 2 0 CAF1 complex subunit p150, region binding to PCNA HSCB_C PF07743.8 XP_011272168.1 - 0.41 11.1 2.6 1.8 9.1 1.2 2.4 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain ABC_tran PF00005.22 XP_011272168.1 - 0.6 10.4 3.1 1.5 9.0 2.1 1.8 1 1 0 1 1 1 0 ABC transporter ParA PF10609.4 XP_011272169.1 - 8.1e-23 80.1 6.9 2.9e-17 62.3 0.9 2.7 1 1 1 2 2 2 2 ParA/MinD ATPase like CbiA PF01656.18 XP_011272169.1 - 4.2e-18 65.4 0.0 6.1e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 XP_011272169.1 - 4e-10 39.2 0.0 7.4e-10 38.3 0.0 1.4 1 1 0 1 1 1 1 ATPase MipZ AAA_31 PF13614.1 XP_011272169.1 - 1.1e-09 38.3 0.0 7e-09 35.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain Fer4_NifH PF00142.13 XP_011272169.1 - 5.3e-07 29.0 0.4 0.00029 20.1 0.0 2.3 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.10 XP_011272169.1 - 1.4e-06 27.5 1.0 1.3e-05 24.3 0.6 2.0 2 0 0 2 2 2 1 Anion-transporting ATPase YhjQ PF06564.7 XP_011272169.1 - 0.0013 18.1 0.4 0.0085 15.4 0.1 1.9 2 0 0 2 2 2 1 YhjQ protein VirC1 PF07015.6 XP_011272169.1 - 0.0047 16.0 0.0 0.0076 15.3 0.0 1.3 1 0 0 1 1 1 1 VirC1 protein APS_kinase PF01583.15 XP_011272169.1 - 0.0061 16.2 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase ArgK PF03308.11 XP_011272169.1 - 0.0081 14.9 0.3 0.014 14.2 0.2 1.3 1 0 0 1 1 1 1 ArgK protein SRP54 PF00448.17 XP_011272169.1 - 0.025 14.0 0.1 0.051 13.0 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_26 PF13500.1 XP_011272169.1 - 0.034 13.7 0.4 0.48 10.0 0.1 2.1 2 0 0 2 2 2 0 AAA domain FTHFS PF01268.14 XP_011272169.1 - 0.075 11.0 0.1 0.11 10.4 0.0 1.2 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase CpXC PF14353.1 XP_011272169.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 CpXC protein AAA_19 PF13245.1 XP_011272169.1 - 0.11 12.3 0.2 4.5 7.0 0.2 2.3 2 0 0 2 2 2 0 Part of AAA domain AAA_25 PF13481.1 XP_011272169.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain Epimerase PF01370.16 XP_011272171.1 - 5.5e-17 61.9 0.0 7.4e-17 61.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 XP_011272171.1 - 1.1e-12 48.2 0.0 1.9e-12 47.5 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 XP_011272171.1 - 1.3e-10 40.9 0.0 2.2e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 XP_011272171.1 - 9.8e-10 37.5 0.0 2.2e-09 36.4 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 XP_011272171.1 - 4e-07 29.2 0.0 6e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 XP_011272171.1 - 3.4e-06 27.0 0.0 4.9e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 XP_011272171.1 - 6.5e-06 25.2 0.0 2.1e-05 23.5 0.0 1.8 1 1 1 2 2 2 1 Male sterility protein TrkA_N PF02254.13 XP_011272171.1 - 3.1e-05 23.9 0.1 5.9e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain KR PF08659.5 XP_011272171.1 - 7.2e-05 22.5 0.1 0.00011 21.9 0.1 1.3 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.12 XP_011272171.1 - 0.00059 20.2 0.0 0.0013 19.1 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 XP_011272171.1 - 0.0043 16.9 0.0 0.0067 16.2 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.11 XP_011272171.1 - 0.017 14.6 0.1 0.032 13.6 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Polysacc_synt_2 PF02719.10 XP_011272171.1 - 0.064 12.1 0.0 0.15 10.9 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.19 XP_011272171.1 - 0.078 13.2 0.1 0.74 10.1 0.0 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Snf7 PF03357.16 XP_011272172.1 - 1.9e-30 105.4 13.0 1.9e-30 105.4 9.0 1.7 2 0 0 2 2 2 1 Snf7 PhoU PF01895.14 XP_011272172.1 - 0.52 10.7 9.2 0.15 12.5 2.2 2.6 2 2 0 2 2 2 0 PhoU domain Opi1 PF08618.5 XP_011272173.1 - 2.4e-44 151.9 0.6 2.5e-29 102.4 3.1 3.3 1 1 1 3 3 3 3 Transcription factor Opi1 TFIIA_gamma_N PF02268.11 XP_011272174.1 - 0.0017 17.9 0.1 0.0039 16.7 0.1 1.6 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain Apis_Csd PF11671.3 XP_011272174.1 - 0.46 10.2 5.0 0.26 11.0 0.7 2.6 2 0 0 2 2 2 0 Complementary sex determiner protein Adap_comp_sub PF00928.16 XP_011272175.1 - 6.3e-59 199.2 0.7 8.4e-59 198.8 0.5 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Nfu_N PF08712.6 XP_011272176.1 - 3e-21 74.8 2.1 3e-21 74.8 1.5 1.7 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 XP_011272176.1 - 4e-21 74.5 0.1 7.8e-21 73.6 0.0 1.5 1 0 0 1 1 1 1 NifU-like domain DUF769 PF05590.6 XP_011272176.1 - 0.11 11.6 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Xylella fastidiosa protein of unknown function (DUF769) Vma12 PF11712.3 XP_011272177.1 - 1.3e-34 118.9 0.3 1.5e-34 118.6 0.2 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase YqhR PF11085.3 XP_011272177.1 - 0.0084 15.6 1.8 0.012 15.1 1.3 1.2 1 0 0 1 1 1 1 Conserved membrane protein YqhR DUF3278 PF11683.3 XP_011272177.1 - 0.012 15.6 1.6 0.017 15.0 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3278) DUF4149 PF13664.1 XP_011272177.1 - 0.019 15.0 0.6 0.058 13.4 0.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4149) Cyt_c_ox_IV PF12270.3 XP_011272177.1 - 0.023 14.4 0.2 0.033 13.9 0.2 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV COPI_assoc PF08507.5 XP_011272177.1 - 0.024 14.3 3.1 0.038 13.6 2.2 1.3 1 0 0 1 1 1 0 COPI associated protein 2TM PF13239.1 XP_011272177.1 - 0.04 13.9 0.7 0.04 13.9 0.5 1.8 2 0 0 2 2 2 0 2TM domain Erf4 PF10256.4 XP_011272177.1 - 3.7 7.4 7.6 11 5.8 1.3 2.6 1 1 1 2 2 2 0 Golgin subfamily A member 7/ERF4 family Prenyltransf PF01255.14 XP_011272178.1 - 1e-72 243.8 2.5 1.3e-72 243.5 1.7 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase CCDC92 PF14916.1 XP_011272178.1 - 0.08 12.5 0.1 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 Coiled-coil domain of unknown function CBS PF00571.23 XP_011272179.1 - 1.7e-37 126.8 3.0 2.7e-10 39.8 0.0 4.7 5 0 0 5 5 5 4 CBS domain PB1 PF00564.19 XP_011272179.1 - 2.9e-07 30.0 1.0 4.3e-07 29.4 0.0 1.9 2 0 0 2 2 2 1 PB1 domain Pneumo_NS1 PF03438.8 XP_011272179.1 - 0.014 15.2 0.0 0.051 13.3 0.0 1.9 1 0 0 1 1 1 0 Pneumovirus NS1 protein Cyt-b5 PF00173.23 XP_011272179.1 - 0.069 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Cytochrome b5-like Heme/Steroid binding domain Ribosomal_L50 PF10501.4 XP_011272180.1 - 4.9e-15 55.4 0.7 4.9e-15 55.4 0.5 2.2 2 0 0 2 2 2 1 Ribosomal subunit 39S E1-E2_ATPase PF00122.15 XP_011272180.1 - 0.057 12.4 0.2 0.1 11.6 0.1 1.4 1 0 0 1 1 1 0 E1-E2 ATPase Bromodomain PF00439.20 XP_011272181.1 - 8.3e-42 141.0 4.1 3.1e-20 71.8 0.1 2.7 2 0 0 2 2 2 2 Bromodomain C2 PF00168.25 XP_011272182.1 - 2.5e-35 120.1 10.7 7.8e-12 44.8 0.0 6.4 6 0 0 6 6 6 5 C2 domain Kdo PF06293.9 XP_011272182.1 - 0.0071 15.4 0.0 0.09 11.8 0.0 2.3 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Dor1 PF04124.7 XP_011272183.1 - 1.2e-35 122.6 18.4 1.2e-34 119.2 10.5 2.2 2 0 0 2 2 2 2 Dor1-like family LAGLIDADG_WhiA PF14527.1 XP_011272183.1 - 0.0097 15.7 2.5 0.06 13.2 0.1 3.0 2 1 1 3 3 3 1 WhiA LAGLIDADG-like domain vATP-synt_AC39 PF01992.11 XP_011272184.1 - 4.7e-100 334.9 0.5 5.4e-100 334.8 0.3 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit cNMP_binding PF00027.24 XP_011272185.1 - 4.4e-33 112.9 0.2 2.3e-17 62.6 0.0 3.2 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain LRR_6 PF13516.1 XP_011272185.1 - 7.3e-11 40.9 9.3 0.69 10.1 0.2 8.7 9 0 0 9 9 9 3 Leucine Rich repeat LRR_1 PF00560.28 XP_011272185.1 - 2e-07 30.1 11.7 27 5.3 0.1 10.3 10 0 0 10 10 10 0 Leucine Rich Repeat F-box-like PF12937.2 XP_011272185.1 - 2e-07 30.6 0.2 4.6e-07 29.4 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 XP_011272185.1 - 1.6e-06 27.5 1.6 6.3e-06 25.7 1.1 2.0 1 0 0 1 1 1 1 F-box domain LRR_7 PF13504.1 XP_011272185.1 - 0.003 17.5 13.4 29 5.4 0.0 7.6 8 0 0 8 8 8 0 Leucine rich repeat HA2 PF04408.18 XP_011272186.1 - 9.3e-21 73.7 0.0 1.9e-20 72.7 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 XP_011272186.1 - 1.1e-16 60.6 0.0 5.7e-16 58.3 0.0 2.2 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 XP_011272186.1 - 8.9e-13 47.9 0.0 3.2e-12 46.1 0.0 2.0 2 0 0 2 2 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 XP_011272186.1 - 2.7e-09 36.7 0.3 5.6e-09 35.7 0.2 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 XP_011272186.1 - 3.9e-08 33.4 0.1 1.4e-07 31.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.9 XP_011272186.1 - 0.00012 21.8 0.1 0.00033 20.4 0.1 1.7 1 0 0 1 1 1 1 Flavivirus DEAD domain SRP54 PF00448.17 XP_011272186.1 - 0.00019 20.9 0.5 0.00056 19.3 0.3 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain ResIII PF04851.10 XP_011272186.1 - 0.0002 21.2 0.5 0.096 12.5 0.0 2.8 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit AAA_30 PF13604.1 XP_011272186.1 - 0.0033 17.0 0.0 0.0064 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain Thioredoxin_8 PF13905.1 XP_011272186.1 - 0.006 16.6 0.0 3.8 7.7 0.0 2.9 2 0 0 2 2 2 1 Thioredoxin-like T2SE PF00437.15 XP_011272186.1 - 0.02 13.8 0.0 0.038 12.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.1 XP_011272186.1 - 0.029 14.7 0.0 0.093 13.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 XP_011272186.1 - 0.17 11.4 0.0 0.43 10.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 XP_011272186.1 - 0.18 12.1 0.3 1.2 9.4 0.1 2.3 1 1 0 2 2 2 0 ABC transporter AAA PF00004.24 XP_011272186.1 - 0.38 10.9 4.8 2.8 8.1 2.2 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC1 PF03109.11 XP_011272187.1 - 5.5e-35 119.9 0.0 1.3e-34 118.6 0.0 1.6 1 0 0 1 1 1 1 ABC1 family DUF1241 PF06840.6 XP_011272187.1 - 0.056 12.6 0.1 0.11 11.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) zf-C2H2 PF00096.21 XP_011272188.1 - 3e-18 64.9 65.7 2.7e-05 24.2 1.8 10.9 10 0 0 10 10 10 6 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 XP_011272188.1 - 1.4e-15 56.6 55.4 6.6e-09 35.6 1.2 8.8 8 1 0 8 8 8 3 Zinc-finger double domain zf-C2H2_jaz PF12171.3 XP_011272188.1 - 3.3e-10 39.7 34.7 0.0011 19.0 0.5 8.3 7 0 0 7 7 7 4 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 XP_011272188.1 - 1.4e-09 37.5 58.5 0.01 16.1 0.1 9.8 9 1 0 9 9 9 5 C2H2-type zinc finger zf-C2H2_6 PF13912.1 XP_011272188.1 - 2.9e-06 26.9 25.4 0.12 12.3 3.3 5.5 5 0 0 5 5 5 4 C2H2-type zinc finger zf-met PF12874.2 XP_011272188.1 - 0.0018 18.4 1.6 0.0018 18.4 1.1 6.4 7 0 0 7 7 7 3 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 XP_011272188.1 - 0.045 13.4 11.7 9.8 5.9 0.6 5.2 4 0 0 4 4 4 0 zinc-finger of a C2HC-type Lysine_decarbox PF03641.9 XP_011272189.1 - 4.1e-42 143.1 0.0 5.3e-42 142.7 0.0 1.1 1 0 0 1 1 1 1 Possible lysine decarboxylase FlbD PF06289.6 XP_011272189.1 - 0.028 13.8 0.1 0.062 12.6 0.1 1.6 1 0 0 1 1 1 0 Flagellar protein (FlbD) Myb_DNA-binding PF00249.26 XP_011272190.1 - 7.5e-27 93.1 0.6 2.5e-13 49.8 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 XP_011272190.1 - 2.1e-19 69.3 1.2 7.1e-13 48.4 0.0 2.8 1 1 1 2 2 2 2 Myb-like DNA-binding domain zf-RING_UBOX PF13445.1 XP_011272191.1 - 0.00032 20.3 0.1 0.0012 18.4 0.1 2.1 1 0 0 1 1 1 1 RING-type zinc-finger adh_short PF00106.20 XP_011272192.1 - 2.3e-28 99.1 0.1 2.9e-28 98.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 XP_011272192.1 - 4.3e-25 88.8 0.1 5.2e-25 88.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 XP_011272192.1 - 1.2e-10 41.3 0.1 1.8e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 XP_011272192.1 - 0.0061 16.0 0.1 0.042 13.2 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 XP_011272192.1 - 0.11 12.1 0.2 0.22 11.1 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HHH_5 PF14520.1 XP_011272192.1 - 0.12 12.5 0.4 3.2 7.9 0.1 2.9 2 2 0 2 2 2 0 Helix-hairpin-helix domain SGL PF08450.7 XP_011272194.1 - 4.9e-135 448.5 0.1 9.2e-68 228.2 0.0 2.1 2 0 0 2 2 2 2 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 XP_011272194.1 - 3e-07 30.3 0.0 0.027 14.4 0.0 2.7 2 0 0 2 2 2 2 Arylesterase PD40 PF07676.7 XP_011272194.1 - 2.4e-06 27.0 0.7 0.058 13.0 0.0 2.7 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat SBP56 PF05694.6 XP_011272194.1 - 0.009 14.5 0.0 1.5 7.2 0.0 2.3 2 0 0 2 2 2 2 56kDa selenium binding protein (SBP56) Reg_prop PF07494.6 XP_011272194.1 - 0.069 13.2 3.4 13 6.2 0.1 4.5 4 0 0 4 4 4 0 Two component regulator propeller SEP PF08059.8 XP_011272194.1 - 0.1 12.9 0.0 28 5.1 0.0 2.6 2 0 0 2 2 2 0 SEP domain Lactonase PF10282.4 XP_011272194.1 - 0.12 11.4 0.0 5.8 5.8 0.0 2.4 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller Foamy_BEL PF03274.9 XP_011272194.1 - 0.16 11.1 0.5 3.1 6.9 0.1 2.2 2 0 0 2 2 2 0 Foamy virus BEL 1/2 protein Cytochrom_C PF00034.16 XP_011272195.1 - 1.1e-09 39.0 0.0 1.8e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 XP_011272195.1 - 5.3e-07 29.7 1.7 2.3e-06 27.6 1.2 1.8 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 XP_011272195.1 - 0.084 12.3 2.2 0.27 10.6 1.5 1.9 1 1 0 1 1 1 0 Cytochrome c-550 domain Cytochrom_C1 PF02167.10 XP_011272195.1 - 0.087 12.4 0.1 0.11 12.1 0.0 1.3 1 1 0 1 1 1 0 Cytochrome C1 family Isy1 PF06246.7 XP_011272196.1 - 3.5e-66 223.2 21.8 3.9e-66 223.0 15.1 1.0 1 0 0 1 1 1 1 Isy1-like splicing family PRESAN PF09687.5 XP_011272196.1 - 0.0075 16.3 7.5 0.0075 16.3 5.2 2.6 2 1 0 2 2 2 1 Plasmodium RESA N-terminal CCDC-167 PF15188.1 XP_011272196.1 - 6.5 6.7 9.1 0.47 10.4 0.1 2.6 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 GDA1_CD39 PF01150.12 XP_011272197.1 - 6.9e-113 377.4 0.0 8.8e-113 377.0 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.11 XP_011272197.1 - 0.03 13.5 0.0 0.048 12.8 0.0 1.2 1 0 0 1 1 1 0 Ppx/GppA phosphatase family RNA_pol_Rpb1_4 PF05000.12 XP_011272197.1 - 0.06 13.0 0.1 0.16 11.6 0.0 1.7 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 4 DUF1547 PF07577.6 XP_011272197.1 - 0.11 12.1 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1547) NAD_kinase PF01513.16 XP_011272198.1 - 1.3e-74 250.5 0.0 2e-74 249.9 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase Ribosomal_L4 PF00573.17 XP_011272198.1 - 0.033 13.5 0.8 0.065 12.6 0.6 1.5 1 0 0 1 1 1 0 Ribosomal protein L4/L1 family DUF3474 PF11960.3 XP_011272198.1 - 1 9.4 4.4 0.33 10.9 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3474) SMAP PF15477.1 XP_011272198.1 - 4.4 7.6 5.4 0.53 10.5 0.3 1.9 2 0 0 2 2 2 0 Small acidic protein family AA_permease PF00324.16 XP_011272199.1 - 5.3e-122 407.5 40.8 6.1e-122 407.3 28.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 XP_011272199.1 - 3.3e-31 108.2 44.5 4.2e-31 107.9 30.9 1.1 1 0 0 1 1 1 1 Amino acid permease DEAD PF00270.24 XP_011272200.1 - 1.2e-45 155.0 0.0 1.9e-44 151.1 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 XP_011272200.1 - 9.5e-29 99.0 0.0 2.3e-28 97.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 XP_011272200.1 - 0.00037 20.3 0.0 0.00068 19.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 XP_011272200.1 - 0.001 17.9 0.0 0.0012 17.6 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain CMS1 PF14617.1 XP_011272200.1 - 0.012 14.6 0.0 0.024 13.7 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DUF1253 PF06862.7 XP_011272200.1 - 0.1 11.0 0.0 0.24 9.7 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) DUF3530 PF12048.3 XP_011272201.1 - 0.37 9.7 6.6 1 8.2 4.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3530) IncA PF04156.9 XP_011272201.1 - 1.2 8.6 4.3 1.7 8.1 3.0 1.3 1 0 0 1 1 1 0 IncA protein IPP-2 PF04979.9 XP_011272202.1 - 7.2e-06 26.2 20.2 0.00021 21.5 6.9 2.6 1 1 1 2 2 2 2 Protein phosphatase inhibitor 2 (IPP-2) DUF3410 PF11890.3 XP_011272202.1 - 0.32 10.6 3.9 2.1 8.0 0.1 2.9 2 2 1 3 3 3 0 Domain of unknown function (DUF3410) Rubredoxin PF00301.15 XP_011272202.1 - 6.6 6.6 6.9 2.3 8.1 0.2 3.4 4 0 0 4 4 4 0 Rubredoxin Acyl_transf_1 PF00698.16 XP_011272203.1 - 3.2e-92 309.2 0.0 1.2e-90 304.1 0.0 3.4 5 0 0 5 5 5 1 Acyl transferase domain MaoC_dehydratas PF01575.14 XP_011272203.1 - 7e-42 141.6 0.0 1.5e-41 140.6 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain DUF1729 PF08354.5 XP_011272203.1 - 1.1e-30 105.1 0.1 2.9e-30 103.8 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 XP_011272203.1 - 2.3e-16 59.7 0.0 1e-15 57.6 0.0 2.1 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase NMO PF03060.10 XP_011272203.1 - 4e-05 22.9 0.1 0.00071 18.8 0.0 2.7 1 1 0 1 1 1 1 Nitronate monooxygenase SRR1 PF07985.7 XP_011272204.1 - 2.2e-20 72.3 0.0 4.4e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 SRR1 Spuma_A9PTase PF03539.9 XP_011272204.1 - 0.083 12.8 0.4 0.23 11.3 0.0 1.9 2 1 0 2 2 2 0 Spumavirus aspartic protease (A9) Elongin_A PF06881.6 XP_011272205.1 - 0.16 12.3 6.8 0.48 10.8 4.7 1.9 1 1 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A FMO-like PF00743.14 XP_011272206.1 - 1.1e-25 89.8 0.0 4.8e-13 48.1 0.1 2.2 1 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 XP_011272206.1 - 1.1e-15 58.2 0.1 3.6e-11 43.5 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 XP_011272206.1 - 8.3e-07 28.2 0.2 0.0001 21.3 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 XP_011272206.1 - 4.8e-05 23.3 0.0 0.92 9.3 0.0 2.9 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 XP_011272206.1 - 0.00051 19.8 0.1 4.7 6.9 0.0 3.5 3 0 0 3 3 3 2 FAD-NAD(P)-binding Mqo PF06039.10 XP_011272206.1 - 0.026 12.7 0.0 0.039 12.1 0.0 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) Pyr_redox PF00070.22 XP_011272206.1 - 0.08 13.3 0.4 12 6.4 0.0 3.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 XP_011272206.1 - 0.21 11.6 0.7 0.95 9.5 0.1 2.4 2 1 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Zn_clus PF00172.13 XP_011272207.1 - 0.0057 16.5 12.3 0.011 15.6 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HMG-CoA_red PF00368.13 XP_011272208.1 - 1.1e-157 524.5 0.3 1.7e-157 523.8 0.2 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.1 XP_011272208.1 - 7.5e-22 77.6 0.1 2.2e-21 76.1 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.3 XP_011272208.1 - 9.6e-10 38.1 3.2 2.5e-09 36.7 2.3 1.7 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 XP_011272208.1 - 0.00043 18.3 7.7 0.00062 17.8 5.4 1.2 1 0 0 1 1 1 1 Patched family FKBP_C PF00254.23 XP_011272209.1 - 1e-27 95.9 0.8 3.2e-27 94.3 0.0 2.3 3 0 0 3 3 3 1 FKBP-type peptidyl-prolyl cis-trans isomerase Nucleoplasmin PF03066.10 XP_011272209.1 - 0.0092 15.5 6.8 0.0092 15.5 4.7 5.0 1 1 3 4 4 4 1 Nucleoplasmin MCPVI PF02993.9 XP_011272209.1 - 0.2 11.7 8.8 0.35 10.9 6.1 1.3 1 0 0 1 1 1 0 Minor capsid protein VI Amino_oxidase PF01593.19 XP_011272209.1 - 0.34 9.9 1.8 0.53 9.2 1.2 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase NAD_binding_10 PF13460.1 XP_011272210.1 - 7.1e-14 52.2 0.0 4.5e-13 49.5 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 XP_011272210.1 - 4.8e-05 22.1 0.0 9e-05 21.3 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 XP_011272210.1 - 8.6e-05 22.0 0.0 0.00015 21.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 XP_011272210.1 - 0.0002 20.3 0.1 0.00076 18.4 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 XP_011272210.1 - 0.014 15.3 0.0 0.13 12.2 0.0 2.1 1 1 0 1 1 1 0 short chain dehydrogenase RmlD_sub_bind PF04321.12 XP_011272210.1 - 0.025 13.4 0.0 1 8.1 0.0 2.5 2 1 0 2 2 2 0 RmlD substrate binding domain AAA_14 PF13173.1 XP_011272210.1 - 0.075 12.9 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain DEAD PF00270.24 XP_011272211.1 - 1e-38 132.4 1.1 1.9e-38 131.6 0.8 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 XP_011272211.1 - 2.3e-21 75.4 0.0 8.3e-11 41.6 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 XP_011272211.1 - 3.9e-06 26.8 0.1 3.9e-06 26.8 0.1 3.0 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit DWNN PF08783.6 XP_011272211.1 - 0.31 11.0 0.0 0.31 11.0 0.0 3.6 5 0 0 5 5 5 0 DWNN domain zf-RING_2 PF13639.1 XP_011272212.1 - 3.7e-10 39.4 7.0 6.6e-10 38.6 4.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 XP_011272212.1 - 2.1e-08 33.7 9.0 4.6e-08 32.6 6.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 XP_011272212.1 - 2.2e-07 30.4 4.1 3.6e-07 29.7 2.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 XP_011272212.1 - 1.6e-05 24.8 8.2 2.9e-05 24.0 5.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 XP_011272212.1 - 9.6e-05 21.9 9.3 0.00022 20.8 6.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Vps39_2 PF10367.4 XP_011272212.1 - 0.0088 16.2 0.1 0.03 14.5 0.0 2.0 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 zf-RING_UBOX PF13445.1 XP_011272212.1 - 0.057 13.1 6.4 0.18 11.5 4.4 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.2 XP_011272212.1 - 0.098 12.7 9.1 0.31 11.1 6.3 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger FANCL_C PF11793.3 XP_011272212.1 - 0.28 11.1 4.8 0.71 9.8 3.3 1.7 1 0 0 1 1 1 0 FANCL C-terminal domain DUF1272 PF06906.6 XP_011272212.1 - 0.59 10.0 3.3 1.2 9.0 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) ETRAMP PF09716.5 XP_011272213.1 - 0.0021 17.9 0.9 0.016 15.1 0.6 2.0 1 1 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) DUF4448 PF14610.1 XP_011272213.1 - 0.029 13.8 0.0 0.034 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) IncA PF04156.9 XP_011272213.1 - 0.048 13.2 0.0 0.057 13.0 0.0 1.1 1 0 0 1 1 1 0 IncA protein UPF0233 PF06781.7 XP_011272213.1 - 0.057 13.0 0.0 0.53 9.9 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0233) DUF912 PF06024.7 XP_011272213.1 - 0.077 13.0 1.8 0.088 12.8 0.5 1.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3899 PF13038.1 XP_011272213.1 - 0.32 11.1 0.2 0.32 11.1 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) Peptidase_S49_N PF08496.5 XP_011272213.1 - 8.3 6.1 7.7 8.4 6.1 4.8 1.3 1 1 0 1 1 1 0 Peptidase family S49 N-terminal zf-RING_2 PF13639.1 XP_011272214.1 - 1.9e-08 33.9 7.3 4.4e-08 32.8 5.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 XP_011272214.1 - 0.00017 21.1 6.4 0.00063 19.3 4.6 1.9 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 XP_011272214.1 - 0.00067 19.6 6.2 0.0013 18.6 4.3 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 XP_011272214.1 - 0.0017 18.0 8.4 0.0026 17.4 5.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 XP_011272214.1 - 0.0043 17.1 6.0 0.25 11.4 5.8 2.5 2 1 0 2 2 2 1 RING-H2 zinc finger zf-RING_2 PF13639.1 XP_011272215.1 - 5.5e-08 32.5 5.4 1.2e-07 31.3 3.7 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 XP_011272215.1 - 0.0016 18.4 6.7 0.0016 18.4 4.6 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 XP_011272215.1 - 0.003 17.2 6.4 0.0055 16.4 4.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 XP_011272215.1 - 0.009 15.6 6.4 0.056 13.1 4.5 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 XP_011272215.1 - 0.042 13.9 6.0 0.12 12.4 4.2 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger SVM_signal PF12113.3 XP_011272215.1 - 0.32 10.8 2.8 2.1 8.2 0.0 2.5 2 0 0 2 2 2 0 SVM protein signal sequence zf-RING_2 PF13639.1 XP_011272216.1 - 4.3e-07 29.6 3.2 9e-07 28.6 2.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 XP_011272216.1 - 0.00065 19.3 2.8 0.0013 18.4 1.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 XP_011272216.1 - 0.00069 19.5 3.5 0.0016 18.4 2.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 XP_011272216.1 - 0.00095 18.7 1.9 0.002 17.7 1.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 XP_011272216.1 - 0.012 15.2 2.3 0.046 13.3 1.6 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF4448 PF14610.1 XP_011272216.1 - 0.024 14.1 0.0 0.039 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF3899 PF13038.1 XP_011272216.1 - 0.036 14.2 0.1 0.27 11.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) Reeler PF02014.11 XP_011272216.1 - 0.07 13.3 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Reeler domain DUF912 PF06024.7 XP_011272216.1 - 0.077 13.0 2.8 0.1 12.6 0.5 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) zf-rbx1 PF12678.2 XP_011272216.1 - 0.25 11.4 2.9 1.1 9.4 2.1 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger PBP1_TM PF14812.1 XP_011272216.1 - 0.37 11.1 3.2 0.42 10.9 0.2 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4286 PF14114.1 XP_011272217.1 - 0.07 13.4 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4286) SR-25 PF10500.4 XP_011272217.1 - 2.6 7.4 12.4 4 6.8 8.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CLP_protease PF00574.18 XP_011272218.1 - 8.2e-71 237.4 0.0 9.6e-71 237.1 0.0 1.0 1 0 0 1 1 1 1 Clp protease SUR7 PF06687.7 XP_011272219.1 - 7.6e-37 126.9 7.2 1.3e-36 126.1 5.0 1.4 1 0 0 1 1 1 1 SUR7/PalI family Wzy_C PF04932.10 XP_011272219.1 - 0.015 15.1 0.6 0.058 13.1 0.4 2.1 1 0 0 1 1 1 0 O-Antigen ligase Claudin_2 PF13903.1 XP_011272219.1 - 0.015 14.9 8.4 0.041 13.5 4.9 2.4 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Fig1 PF12351.3 XP_011272219.1 - 3.7 7.3 5.0 6.6 6.5 3.5 1.3 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 zf-C2H2_4 PF13894.1 XP_011272220.1 - 0.063 13.6 10.0 1.8 9.0 0.0 3.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.21 XP_011272220.1 - 1.9 8.9 16.4 19 5.8 0.1 4.4 3 1 0 3 3 3 0 Zinc finger, C2H2 type MFS_1 PF07690.11 XP_011272222.1 - 1e-23 83.6 5.6 1.2e-23 83.4 3.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 XP_011272222.1 - 0.00014 20.5 17.6 0.0003 19.5 12.2 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter FPN1 PF06963.7 XP_011272222.1 - 0.00055 18.4 0.9 0.00088 17.7 0.0 1.6 2 0 0 2 2 2 1 Ferroportin1 (FPN1) DUF2207 PF09972.4 XP_011272222.1 - 0.064 11.8 2.6 0.64 8.5 0.1 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF3784 PF12650.2 XP_011272222.1 - 5 7.1 9.6 0.48 10.4 0.8 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF3784) Fungal_trans_2 PF11951.3 XP_011272223.1 - 1.1e-07 30.7 0.1 1.6e-06 26.9 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 XP_011272223.1 - 2.2e-05 24.2 13.7 5.2e-05 23.0 9.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidase PF01425.16 XP_011272224.1 - 2e-85 287.3 0.0 2.4e-85 287.0 0.0 1.1 1 0 0 1 1 1 1 Amidase Zn_clus PF00172.13 XP_011272225.1 - 7.2e-05 22.6 10.2 0.00016 21.5 7.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidase PF01425.16 XP_011272226.1 - 6.2e-83 279.0 0.0 7.7e-83 278.7 0.0 1.1 1 0 0 1 1 1 1 Amidase MFS_1 PF07690.11 XP_011272227.1 - 3e-31 108.4 30.4 8.5e-31 106.9 11.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 XP_011272227.1 - 4e-05 22.3 12.2 4e-05 22.3 8.5 2.8 3 1 0 3 3 3 1 Sugar (and other) transporter DUF4191 PF13829.1 XP_011272227.1 - 8.9 5.3 6.6 4.7 6.2 1.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Abhydrolase_6 PF12697.2 XP_011272228.1 - 4.8e-13 49.5 0.0 5.8e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 XP_011272228.1 - 4.1e-12 45.7 0.1 5.7e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_5 PF12695.2 XP_011272228.1 - 3.6e-11 43.0 0.0 4.4e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 XP_011272228.1 - 6.3e-09 35.7 0.2 9.5e-09 35.1 0.0 1.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold Chlorophyllase PF07224.6 XP_011272228.1 - 4.1e-05 22.5 0.0 5.2e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.2 XP_011272228.1 - 0.00071 18.5 0.0 0.00092 18.1 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme LCAT PF02450.10 XP_011272228.1 - 0.0015 17.5 0.0 0.0021 17.1 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Esterase PF00756.15 XP_011272228.1 - 0.0022 17.4 0.0 0.0029 17.0 0.0 1.3 1 0 0 1 1 1 1 Putative esterase PGAP1 PF07819.8 XP_011272228.1 - 0.0022 17.6 0.0 0.0033 17.0 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein AXE1 PF05448.7 XP_011272228.1 - 0.014 13.9 0.0 0.39 9.1 0.0 2.0 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) DUF2305 PF10230.4 XP_011272228.1 - 0.018 14.4 0.0 0.02 14.3 0.0 1.3 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) DUF900 PF05990.7 XP_011272228.1 - 0.053 12.8 0.0 0.084 12.1 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Lipase_3 PF01764.20 XP_011272228.1 - 0.072 12.6 0.0 0.081 12.5 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_3 PF07859.8 XP_011272228.1 - 0.1 12.1 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 XP_011272230.1 - 0.0018 18.0 0.0 0.003 17.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Imm20 PF15568.1 XP_011272230.1 - 0.11 12.3 0.1 0.27 11.1 0.1 1.7 1 0 0 1 1 1 0 Immunity protein 20 MIT PF04212.13 XP_011272232.1 - 0.00052 19.8 0.4 0.0077 16.0 0.1 2.9 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain Pkinase PF00069.20 XP_011272234.1 - 1.7e-56 191.2 9.7 5.3e-40 137.1 0.1 2.9 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011272234.1 - 3.5e-25 88.5 9.5 1.7e-20 73.2 0.0 3.2 2 1 0 3 3 3 2 Protein tyrosine kinase Pkinase_C PF00433.19 XP_011272234.1 - 0.011 16.2 0.4 0.011 16.2 0.3 2.7 2 1 0 2 2 2 0 Protein kinase C terminal domain APH PF01636.18 XP_011272234.1 - 0.25 11.0 7.4 0.83 9.3 0.1 3.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family Ribosomal_L44 PF00935.14 XP_011272235.1 - 1.8e-34 117.5 11.2 3e-34 116.8 7.8 1.4 1 0 0 1 1 1 1 Ribosomal protein L44 Chs3p PF12271.3 XP_011272236.1 - 4.9e-109 363.8 16.9 6e-109 363.5 11.7 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit FA_desaturase PF00487.19 XP_011272236.1 - 5.7 6.3 6.5 9.5 5.5 4.5 1.4 1 0 0 1 1 1 0 Fatty acid desaturase Metallophos PF00149.23 XP_011272237.1 - 1.7e-12 47.1 3.0 1.7e-12 47.1 2.1 2.5 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 XP_011272237.1 - 8.8e-05 22.3 0.0 0.00043 20.1 0.0 2.0 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain GTP_EFTU PF00009.22 XP_011272238.1 - 1.8e-54 184.0 0.0 2.4e-53 180.3 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 XP_011272238.1 - 2.6e-15 56.0 0.0 7.2e-15 54.6 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 XP_011272238.1 - 1.2e-10 41.0 0.0 3.1e-10 39.7 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 XP_011272238.1 - 7.4e-09 35.6 0.7 2.5e-08 33.9 0.1 2.3 2 1 0 2 2 2 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 XP_011272238.1 - 0.02 14.4 0.0 0.071 12.6 0.0 2.0 1 0 0 1 1 1 0 Elongation factor G, domain IV ChaC PF04752.7 XP_011272239.1 - 0.065 13.1 0.0 0.096 12.6 0.0 1.4 1 0 0 1 1 1 0 ChaC-like protein CactinC_cactus PF09732.4 XP_011272240.1 - 0.022 14.3 0.1 0.045 13.3 0.1 1.4 1 0 0 1 1 1 0 Cactus-binding C-terminus of cactin protein Mnd1 PF03962.10 XP_011272241.1 - 0.0053 16.4 2.3 0.0053 16.4 1.6 1.8 2 0 0 2 2 2 1 Mnd1 family Snapin_Pallidin PF14712.1 XP_011272241.1 - 0.0055 16.9 3.4 0.018 15.3 2.4 1.9 1 0 0 1 1 1 1 Snapin/Pallidin Seryl_tRNA_N PF02403.17 XP_011272241.1 - 0.026 14.5 7.1 0.026 14.5 4.9 2.0 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Prefoldin PF02996.12 XP_011272241.1 - 0.048 13.3 8.3 0.13 11.9 1.7 2.8 1 1 1 2 2 2 0 Prefoldin subunit TMF_DNA_bd PF12329.3 XP_011272241.1 - 0.19 11.5 15.5 0.098 12.4 7.3 2.8 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF1192 PF06698.6 XP_011272241.1 - 0.25 11.1 1.9 3.5 7.5 0.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) DUF342 PF03961.8 XP_011272241.1 - 0.25 9.7 10.3 0.0095 14.3 3.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF342) DUF4140 PF13600.1 XP_011272241.1 - 0.34 11.3 0.1 0.34 11.3 0.1 3.0 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) 3HCDH_N PF02737.13 XP_011272241.1 - 0.54 9.8 5.7 0.7 9.5 1.0 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Kinesin-relat_1 PF12711.2 XP_011272241.1 - 0.92 9.9 8.0 0.47 10.8 2.8 2.1 2 0 0 2 2 2 0 Kinesin motor IncA PF04156.9 XP_011272241.1 - 1.6 8.3 5.5 0.22 11.0 0.3 2.0 2 0 0 2 2 2 0 IncA protein LUC7 PF03194.10 XP_011272241.1 - 5 6.5 8.1 0.47 9.9 1.2 2.0 2 0 0 2 2 2 0 LUC7 N_terminus Allexi_40kDa PF05549.6 XP_011272241.1 - 9.5 5.4 8.7 1.1 8.5 0.4 2.2 2 0 0 2 2 2 0 Allexivirus 40kDa protein CDO_I PF05995.7 XP_011272242.1 - 2.9e-28 98.2 0.1 3.7e-28 97.8 0.1 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 XP_011272242.1 - 0.058 12.7 0.1 0.092 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1637) Cupin_2 PF07883.6 XP_011272242.1 - 0.11 12.0 0.0 0.47 9.9 0.0 1.9 2 0 0 2 2 2 0 Cupin domain CTDII PF01556.13 XP_011272243.1 - 5.4e-25 87.0 3.0 4.6e-20 71.2 0.4 2.9 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 XP_011272243.1 - 1.2e-23 82.6 3.6 2.4e-23 81.6 2.5 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 XP_011272243.1 - 1.4e-12 47.4 19.3 2.5e-12 46.6 13.4 1.4 1 0 0 1 1 1 1 DnaJ central domain DUF2318 PF10080.4 XP_011272243.1 - 0.44 10.3 9.6 3.5 7.4 6.7 2.2 1 1 1 2 2 2 0 Predicted membrane protein (DUF2318) Cytochrom_c3_2 PF14537.1 XP_011272243.1 - 1.2 9.5 10.0 4.3 7.7 6.9 2.0 1 1 0 1 1 1 0 Cytochrome c3 Antiterm PF03589.8 XP_011272243.1 - 1.4 9.0 12.4 8.3 6.5 0.2 3.5 1 1 2 3 3 3 0 Antitermination protein RabGAP-TBC PF00566.13 XP_011272244.1 - 6.7e-19 68.2 6.0 6.7e-19 68.2 4.2 1.9 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Ran_BP1 PF00638.13 XP_011272245.1 - 8.9e-24 83.8 0.1 1.7e-23 82.9 0.1 1.5 1 0 0 1 1 1 1 RanBP1 domain NUP50 PF08911.6 XP_011272245.1 - 1e-11 45.0 11.2 1e-11 45.0 7.7 7.1 5 3 1 6 6 6 1 NUP50 (Nucleoporin 50 kDa) Ribosomal_S25 PF03297.10 XP_011272246.1 - 1.1e-44 150.7 4.8 1.2e-44 150.6 3.3 1.0 1 0 0 1 1 1 1 S25 ribosomal protein Ftsk_gamma PF09397.5 XP_011272246.1 - 0.00023 20.8 0.3 0.00037 20.1 0.2 1.4 1 0 0 1 1 1 1 Ftsk gamma domain GntR PF00392.16 XP_011272246.1 - 0.001 18.4 0.2 0.0017 17.7 0.1 1.2 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family HTH_DeoR PF08220.7 XP_011272246.1 - 0.031 13.8 0.0 0.05 13.1 0.0 1.2 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain TAF4 PF05236.9 XP_011272246.1 - 0.089 12.0 2.6 0.11 11.7 1.8 1.2 1 1 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family FAD_binding_1 PF00667.15 XP_011272247.1 - 1.2e-64 217.7 0.0 2e-64 217.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 XP_011272247.1 - 1.9e-10 41.2 0.0 6.1e-10 39.6 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Casc1 PF12366.3 XP_011272247.1 - 0.00062 19.3 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 Cancer susceptibility candidate 1 Arm PF00514.18 XP_011272248.1 - 6.3e-08 32.1 3.4 0.025 14.4 0.0 5.0 4 0 0 4 4 4 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 XP_011272248.1 - 0.00014 22.0 0.0 0.59 10.4 0.0 4.0 4 0 0 4 4 4 2 HEAT repeats HEAT PF02985.17 XP_011272248.1 - 0.0058 16.6 1.2 0.61 10.3 0.0 4.1 4 0 0 4 4 4 1 HEAT repeat Tyr-DNA_phospho PF06087.7 XP_011272249.1 - 1.9e-86 290.4 3.1 2.3e-86 290.2 2.1 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 XP_011272249.1 - 0.00072 19.3 0.2 0.47 10.2 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain Asp_Glu_race PF01177.17 XP_011272250.1 - 2.2e-06 27.7 0.1 6.7e-06 26.1 0.1 1.6 1 1 0 1 1 1 1 Asp/Glu/Hydantoin racemase DAO PF01266.19 XP_011272251.1 - 2.8e-33 115.2 0.0 4.8e-33 114.5 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 XP_011272251.1 - 0.00017 21.5 0.0 0.015 15.1 0.0 2.5 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 XP_011272251.1 - 0.0003 20.7 0.0 0.00065 19.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 XP_011272251.1 - 0.00066 19.7 0.0 0.014 15.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 XP_011272251.1 - 0.0022 16.9 0.0 0.032 13.0 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_9 PF13454.1 XP_011272251.1 - 0.0026 17.5 0.0 0.53 10.0 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding ThiF PF00899.16 XP_011272251.1 - 0.031 14.1 0.0 0.075 12.8 0.0 1.6 1 0 0 1 1 1 0 ThiF family Pyr_redox PF00070.22 XP_011272251.1 - 0.076 13.4 0.3 1.6 9.1 0.0 3.0 4 0 0 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 XP_011272251.1 - 0.098 11.1 0.0 4.4 5.6 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.19 XP_011272251.1 - 0.16 10.8 0.0 0.24 10.1 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain MFS_1 PF07690.11 XP_011272252.1 - 1.5e-18 66.6 27.7 1.5e-18 66.6 19.2 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Homeobox_KN PF05920.6 XP_011272253.1 - 2.1e-14 52.9 1.3 2.1e-14 52.9 0.9 2.6 2 0 0 2 2 2 1 Homeobox KN domain Homeobox PF00046.24 XP_011272253.1 - 1.9e-07 30.5 1.5 9.7e-07 28.3 1.0 2.2 1 0 0 1 1 1 1 Homeobox domain PAT1 PF09770.4 XP_011272253.1 - 0.18 10.0 41.4 0.23 9.6 28.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GAGA_bind PF06217.7 XP_011272253.1 - 4.5 7.1 23.6 9.2 6.1 16.3 1.6 1 1 0 1 1 1 0 GAGA binding protein-like family RRM_1 PF00076.17 XP_011272254.1 - 2.7e-16 58.9 0.0 4.3e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 XP_011272254.1 - 8.9e-10 38.4 0.0 1.4e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 XP_011272254.1 - 3.4e-07 29.9 0.0 5.8e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Metallophos PF00149.23 XP_011272255.1 - 4.4e-42 143.7 0.4 4.4e-42 143.7 0.2 1.5 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 XP_011272255.1 - 0.0016 18.2 0.0 0.0031 17.3 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain GATA PF00320.22 XP_011272256.1 - 1.6e-16 59.3 5.0 3.1e-16 58.4 3.5 1.5 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.7 XP_011272256.1 - 0.073 12.3 1.1 0.16 11.3 0.8 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding ADH_N PF08240.7 XP_011272257.1 - 2.6e-31 107.6 0.6 4.7e-31 106.7 0.1 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 XP_011272257.1 - 1.6e-30 105.2 0.1 2.5e-30 104.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 XP_011272257.1 - 2.8e-05 25.0 0.1 8.6e-05 23.4 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ACP_syn_III_C PF08541.5 XP_011272257.1 - 0.091 12.7 0.2 0.2 11.7 0.1 1.5 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal DUF3074 PF11274.3 XP_011272258.1 - 2.3e-32 112.1 0.1 3.4e-32 111.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) START PF01852.14 XP_011272258.1 - 0.022 14.0 0.0 0.054 12.8 0.0 1.6 1 0 0 1 1 1 0 START domain Transketolase_N PF00456.16 XP_011272259.1 - 5.2e-152 505.4 0.0 1.2e-151 504.2 0.0 1.5 2 0 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 XP_011272259.1 - 4.3e-48 163.1 0.0 7.3e-48 162.4 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 XP_011272259.1 - 5.4e-14 52.1 0.0 1.2e-13 51.0 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 XP_011272259.1 - 1.6e-08 33.7 0.0 0.00041 19.3 0.0 2.6 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.16 XP_011272259.1 - 7.4e-05 22.3 0.0 0.0006 19.4 0.0 2.3 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.15 XP_011272259.1 - 0.00052 18.8 0.0 0.00095 17.9 0.0 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component LMWPc PF01451.16 XP_011272263.1 - 6.7e-35 120.4 0.0 7.7e-35 120.2 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Pkinase_Tyr PF07714.12 XP_011272264.1 - 0.021 13.9 0.2 0.068 12.2 0.0 1.9 2 0 0 2 2 2 0 Protein tyrosine kinase RIO1 PF01163.17 XP_011272264.1 - 0.036 13.4 0.1 0.036 13.4 0.0 2.9 3 0 0 3 3 3 0 RIO1 family Not3 PF04065.10 XP_011272265.1 - 2.6e-89 298.5 33.8 4e-89 297.8 23.4 1.3 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 XP_011272265.1 - 5.8e-25 87.7 5.1 5.8e-25 87.7 3.5 2.2 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family NAD_binding_4 PF07993.7 XP_011272266.1 - 4.7e-72 241.8 0.0 6.9e-72 241.3 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 XP_011272266.1 - 3.9e-71 239.6 0.0 5.4e-71 239.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 XP_011272266.1 - 2.5e-14 53.2 0.0 1.8e-13 50.5 0.0 2.4 2 0 0 2 2 2 1 Phosphopantetheine attachment site Epimerase PF01370.16 XP_011272266.1 - 7.6e-14 51.7 0.0 1.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 XP_011272266.1 - 3.8e-11 42.2 0.0 8.2e-11 41.1 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.1 XP_011272266.1 - 1.1e-07 32.6 0.1 6.1e-07 30.2 0.0 2.4 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain NAD_binding_10 PF13460.1 XP_011272266.1 - 0.00011 22.2 0.0 0.00093 19.2 0.0 2.3 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 XP_011272266.1 - 0.0018 17.2 0.0 0.0034 16.3 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Condensation PF00668.15 XP_011272266.1 - 0.0019 17.1 0.2 0.063 12.1 0.0 2.5 2 0 0 2 2 2 1 Condensation domain NmrA PF05368.8 XP_011272266.1 - 0.015 14.5 0.0 0.029 13.6 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family RmlD_sub_bind PF04321.12 XP_011272266.1 - 0.047 12.5 0.0 0.39 9.5 0.0 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain SNF2_N PF00176.18 XP_011272267.1 - 6.5e-70 235.2 0.1 8.7e-70 234.8 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 XP_011272267.1 - 9.4e-11 41.4 0.0 1.9e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 XP_011272267.1 - 3.6e-09 36.1 9.0 3.6e-09 36.1 6.2 2.3 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.10 XP_011272267.1 - 6.8e-08 32.5 1.3 3.4e-07 30.2 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.24 XP_011272267.1 - 4.3e-06 26.3 0.0 8.5e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4_2 PF13923.1 XP_011272267.1 - 1.4e-05 24.9 8.0 1.4e-05 24.9 5.6 2.7 2 1 1 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 XP_011272267.1 - 2.3e-05 24.1 7.9 2.3e-05 24.1 5.5 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.1 XP_011272267.1 - 0.00015 21.5 8.8 0.00015 21.5 6.1 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 XP_011272267.1 - 0.00079 19.0 7.0 0.00079 19.0 4.9 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 XP_011272267.1 - 0.0022 17.7 8.7 0.0022 17.7 6.0 2.3 2 0 0 2 2 2 1 zinc-RING finger domain Zn_Tnp_IS91 PF14319.1 XP_011272267.1 - 0.057 12.9 9.4 0.18 11.3 0.6 2.5 2 0 0 2 2 2 0 Transposase zinc-binding domain zf-RING_6 PF14835.1 XP_011272267.1 - 0.13 12.1 2.6 0.3 10.9 1.8 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein HypA PF01155.14 XP_011272267.1 - 1.4 8.6 7.2 1.2 8.8 0.8 2.5 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family LZ_Tnp_IS66 PF13007.2 XP_011272267.1 - 1.9 9.1 10.9 3.6 8.2 1.8 2.8 2 0 0 2 2 2 0 Transposase C of IS166 homeodomain FLO_LFY PF01698.11 XP_011272267.1 - 4.5 6.0 9.1 7.6 5.2 6.3 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein Fungal_trans PF04082.13 XP_011272268.1 - 8.9e-12 44.4 6.2 8.9e-12 44.4 4.3 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 XP_011272268.1 - 1e-06 28.5 14.7 1.7e-06 27.8 10.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Med15_fungi PF05397.7 XP_011272269.1 - 6.2e-29 100.3 2.5 6.2e-29 100.3 1.8 8.5 7 2 3 10 10 10 2 Mediator complex subunit 15 Pkinase PF00069.20 XP_011272270.1 - 4.9e-60 202.8 0.2 1.1e-59 201.6 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011272270.1 - 5.1e-22 78.1 0.0 9.3e-22 77.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PAS_9 PF13426.1 XP_011272270.1 - 1.9e-05 24.9 0.0 0.14 12.5 0.0 2.9 2 0 0 2 2 2 2 PAS domain Kinase-like PF14531.1 XP_011272270.1 - 2.2e-05 23.5 0.0 5.2e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Kinase-like PAS PF00989.19 XP_011272270.1 - 0.0011 18.7 0.0 0.35 10.6 0.0 3.0 2 0 0 2 2 2 1 PAS fold APH PF01636.18 XP_011272270.1 - 0.013 15.2 0.6 0.024 14.3 0.4 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family PAS_8 PF13188.1 XP_011272270.1 - 0.066 13.0 0.0 0.48 10.3 0.0 2.3 2 0 0 2 2 2 0 PAS domain Y_phosphatase3 PF13350.1 XP_011272271.1 - 4e-45 154.0 0.0 9.5e-45 152.7 0.0 1.7 2 0 0 2 2 2 1 Tyrosine phosphatase family Abhydrolase_5 PF12695.2 XP_011272271.1 - 1.9e-10 40.6 0.0 3.5e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Y_phosphatase3C PF13348.1 XP_011272271.1 - 2.4e-08 33.9 0.0 4.5e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Abhydrolase_6 PF12697.2 XP_011272271.1 - 2.1e-05 24.4 0.0 0.00078 19.3 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 XP_011272271.1 - 6.9e-05 22.6 0.0 0.00015 21.5 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Y_phosphatase2 PF03162.8 XP_011272271.1 - 0.00013 21.3 0.0 0.0003 20.1 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family ApbA PF02558.11 XP_011272277.1 - 2.4e-28 98.4 0.1 5.1e-28 97.4 0.0 1.6 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 XP_011272277.1 - 2.4e-26 92.1 0.1 3.4e-26 91.6 0.1 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal NAD_Gly3P_dh_N PF01210.18 XP_011272277.1 - 0.0024 17.6 0.1 0.029 14.1 0.0 2.5 2 1 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F_actin_bind PF08919.5 XP_011272277.1 - 0.086 12.5 0.3 0.28 10.8 0.0 2.1 2 1 0 2 2 2 0 F-actin binding Saccharop_dh PF03435.13 XP_011272277.1 - 0.13 11.2 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Peptidase_M20 PF01546.23 XP_011272278.1 - 9.4e-33 113.3 0.0 1.4e-32 112.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 XP_011272278.1 - 6.6e-14 51.6 0.0 1.2e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Lyase_1 PF00206.15 XP_011272281.1 - 2.1e-119 398.3 0.0 2.8e-119 397.9 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 XP_011272281.1 - 2.9e-23 81.6 0.1 1e-22 79.9 0.0 1.9 2 0 0 2 2 2 1 Fumarase C C-terminus ADH_N PF08240.7 XP_011272281.1 - 0.044 13.5 0.0 0.091 12.5 0.0 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain DUF1241 PF06840.6 XP_011272281.1 - 0.051 12.8 0.1 0.12 11.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) PMT PF02366.13 XP_011272283.1 - 3.6e-90 301.6 18.6 3.6e-90 301.6 12.9 2.3 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 XP_011272283.1 - 1.6e-28 99.5 2.0 1.6e-28 99.5 1.4 1.8 2 1 0 2 2 2 1 MIR domain LDB19 PF13002.2 XP_011272285.1 - 7e-72 240.9 0.3 1.2e-71 240.2 0.2 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.24 XP_011272285.1 - 1.3e-05 25.0 1.6 1.7e-05 24.7 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Exo_endo_phos PF03372.18 XP_011272286.1 - 1.3e-24 87.4 0.2 2.2e-24 86.7 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 XP_011272286.1 - 1.1e-13 50.4 12.1 3.9e-10 39.1 4.9 4.4 5 0 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 XP_011272286.1 - 4.9e-10 38.0 14.5 0.025 14.5 0.9 6.1 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_8 PF13855.1 XP_011272286.1 - 1.3e-09 37.6 10.9 9.1e-09 34.9 6.1 3.0 2 1 1 3 3 3 2 Leucine rich repeat LRR_7 PF13504.1 XP_011272286.1 - 6e-08 31.6 7.0 0.4 11.0 0.6 5.3 3 0 0 3 3 3 3 Leucine rich repeat LRR_6 PF13516.1 XP_011272286.1 - 0.00085 19.1 7.6 0.27 11.3 0.5 4.5 3 0 0 3 3 3 1 Leucine Rich repeat F-box-like PF12937.2 XP_011272287.1 - 0.027 14.2 0.0 0.057 13.1 0.0 1.6 1 0 0 1 1 1 0 F-box-like ADH_N PF08240.7 XP_011272288.1 - 2e-30 104.7 0.3 3.3e-30 104.0 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 XP_011272288.1 - 1.3e-13 50.6 0.0 1.8e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase GBV-C_env PF12786.2 XP_011272288.1 - 0.068 11.6 0.0 0.098 11.1 0.0 1.1 1 0 0 1 1 1 0 GB virus C genotype envelope Sugar_tr PF00083.19 XP_011272289.1 - 8.6e-103 344.3 25.0 1e-102 344.0 17.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 XP_011272289.1 - 6.2e-18 64.6 38.7 2e-15 56.4 6.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 XP_011272289.1 - 0.00048 18.3 1.3 0.00092 17.3 0.9 1.4 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family adh_short_C2 PF13561.1 XP_011272290.1 - 3.5e-27 95.7 0.0 4.6e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 XP_011272290.1 - 4.5e-21 75.4 0.0 5.8e-21 75.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 XP_011272290.1 - 3.2e-07 30.2 0.0 5.6e-07 29.3 0.0 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 XP_011272290.1 - 0.0099 15.3 0.1 0.043 13.2 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 XP_011272290.1 - 0.029 14.1 0.1 0.063 13.0 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3Beta_HSD PF01073.14 XP_011272290.1 - 0.077 11.6 0.6 0.13 10.9 0.4 1.4 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family LacAB_rpiB PF02502.13 XP_011272291.1 - 1.9e-42 144.2 0.1 2.2e-42 144.0 0.1 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase Gly_rich_SFCGS PF14272.1 XP_011272291.1 - 0.0019 18.0 0.0 0.0025 17.6 0.0 1.3 1 1 0 1 1 1 1 Glycine-rich SFCGS Dak1 PF02733.12 XP_011272292.1 - 4.3e-90 301.5 0.2 8.9e-90 300.5 0.0 1.5 2 0 0 2 2 2 1 Dak1 domain Dak2 PF02734.12 XP_011272292.1 - 9.1e-38 129.6 0.0 1.4e-37 129.0 0.0 1.3 1 0 0 1 1 1 1 DAK2 domain Keratin_assoc PF09775.4 XP_011272292.1 - 0.49 9.9 3.7 0.36 10.3 0.1 2.3 3 0 0 3 3 3 0 Keratinocyte-associated protein 2 Fungal_trans PF04082.13 XP_011272293.1 - 1.9e-19 69.5 8.5 7.7e-19 67.5 5.9 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 XP_011272293.1 - 1.3e-06 28.3 8.8 0.002 18.3 0.6 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 XP_011272293.1 - 1.6e-05 24.8 4.5 0.00096 19.2 0.2 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 XP_011272293.1 - 0.00047 20.2 7.8 0.19 12.1 0.7 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 XP_011272293.1 - 0.0023 18.0 3.2 0.0029 17.7 0.3 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 XP_011272293.1 - 0.0035 17.5 1.1 0.0035 17.5 0.7 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_2 PF12756.2 XP_011272293.1 - 0.04 14.0 2.2 0.37 10.9 0.8 2.6 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Epimerase PF01370.16 XP_011272294.1 - 3.6e-20 72.3 0.1 5e-20 71.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 XP_011272294.1 - 3e-14 52.3 1.0 5.4e-14 51.5 0.7 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 XP_011272294.1 - 3.2e-11 42.6 0.0 1.5e-10 40.4 0.0 2.0 2 1 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.1 XP_011272294.1 - 6.4e-09 36.0 0.0 9.7e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 XP_011272294.1 - 2.7e-05 24.1 0.0 4.1e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 XP_011272294.1 - 0.00068 19.3 0.0 0.001 18.7 0.0 1.3 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 XP_011272294.1 - 0.0038 16.5 0.2 0.0088 15.3 0.1 1.7 1 1 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 XP_011272294.1 - 0.013 14.3 0.0 0.053 12.4 0.0 1.8 1 1 0 1 1 1 0 RmlD substrate binding domain MFS_1 PF07690.11 XP_011272295.1 - 6.6e-07 28.3 0.1 9.1e-07 27.8 0.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1298 PF06974.8 XP_011272295.1 - 0.098 12.4 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1298) Mg296 PF09644.5 XP_011272296.1 - 0.016 15.0 0.4 0.029 14.2 0.3 1.5 1 0 0 1 1 1 0 Mg296 protein Esterase PF00756.15 XP_011272296.1 - 0.093 12.1 0.1 0.14 11.5 0.1 1.2 1 0 0 1 1 1 0 Putative esterase Ferric_reduct PF01794.14 XP_011272299.1 - 1.2e-16 60.9 1.5 2.1e-16 60.1 1.1 1.4 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 XP_011272299.1 - 4.2e-10 39.4 0.0 7e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 XP_011272299.1 - 1.9e-07 31.1 0.4 2.8e-07 30.5 0.3 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain DUF3573 PF12097.3 XP_011272300.1 - 0.37 9.3 7.8 0.27 9.8 4.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3573) Methyltransf_4 PF02390.12 XP_011272301.1 - 5.8e-59 198.4 0.6 1.1e-58 197.5 0.4 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.1 XP_011272301.1 - 3.7e-06 26.5 0.1 9.2e-06 25.3 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 XP_011272301.1 - 4.8e-05 23.9 0.0 8.4e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 XP_011272301.1 - 0.00088 18.6 0.0 0.0021 17.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 XP_011272301.1 - 0.0014 19.0 0.4 0.0082 16.5 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.13 XP_011272301.1 - 0.0017 17.5 0.0 0.0055 15.8 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 XP_011272301.1 - 0.0076 16.2 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 XP_011272301.1 - 0.039 14.3 0.0 0.1 12.9 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.1 XP_011272301.1 - 0.043 13.5 0.0 0.13 12.0 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain FmrO PF07091.6 XP_011272301.1 - 0.048 12.6 0.0 0.089 11.7 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) DUF2431 PF10354.4 XP_011272301.1 - 0.086 12.7 0.8 0.14 12.0 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) Methyltransf_32 PF13679.1 XP_011272301.1 - 0.1 12.2 0.2 0.34 10.6 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain DUF748 PF05359.6 XP_011272302.1 - 0.043 13.8 5.2 1.5 8.8 0.6 3.1 3 0 0 3 3 3 0 Domain of Unknown Function (DUF748) Sad1_UNC PF07738.8 XP_011272303.1 - 3.4e-09 36.6 0.1 8.4e-09 35.3 0.1 1.7 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal DUF976 PF06162.7 XP_011272304.1 - 0.075 12.5 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Caenorhabditis elegans protein of unknown function (DUF976) CPSF_A PF03178.10 XP_011272305.1 - 2e-79 267.0 0.2 2e-79 267.0 0.1 3.4 4 0 0 4 4 4 1 CPSF A subunit region Glyco_transf_28 PF03033.15 XP_011272306.1 - 5.1e-27 94.3 0.0 1.1e-26 93.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.15 XP_011272306.1 - 2.7e-22 78.0 2.9 1.2e-13 50.3 0.1 3.9 4 0 0 4 4 4 2 GRAM domain UDPGT PF00201.13 XP_011272306.1 - 7.2e-09 34.7 0.0 1.8e-08 33.4 0.0 1.6 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH PF00169.24 XP_011272306.1 - 8.2e-07 29.1 0.3 1.6e-05 25.0 0.0 3.3 2 1 1 3 3 3 1 PH domain PH_11 PF15413.1 XP_011272306.1 - 0.0043 17.2 0.6 0.098 12.9 0.0 3.2 2 0 0 2 2 2 1 Pleckstrin homology domain Glyco_tran_28_C PF04101.11 XP_011272306.1 - 0.03 13.9 0.0 0.079 12.6 0.0 1.7 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 XP_011272306.1 - 0.13 11.4 0.0 0.29 10.3 0.0 1.6 2 0 0 2 2 2 0 Glycosyl transferase family 1 Abhydrolase_1 PF00561.15 XP_011272307.1 - 1.1e-48 165.8 0.0 2.6e-48 164.6 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 XP_011272307.1 - 9.3e-09 35.4 0.0 4.1e-08 33.4 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 XP_011272307.1 - 0.002 16.8 0.0 0.0032 16.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 XP_011272307.1 - 0.0092 15.7 0.0 0.1 12.3 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 XP_011272307.1 - 0.039 13.8 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 TAP-like protein Exo_endo_phos PF03372.18 XP_011272308.1 - 2e-19 70.4 0.1 2.8e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF3124 PF11322.3 XP_011272308.1 - 0.12 12.3 0.1 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3124) Spindle_Spc25 PF08234.7 XP_011272309.1 - 4.4e-18 65.0 3.0 6.1e-18 64.6 0.3 2.5 2 1 0 2 2 2 1 Chromosome segregation protein Spc25 IFT57 PF10498.4 XP_011272309.1 - 0.0088 14.8 16.1 0.017 13.8 11.2 1.5 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 DUF2353 PF09789.4 XP_011272309.1 - 0.13 11.4 22.6 0.041 13.1 12.3 1.9 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) Reo_sigmaC PF04582.7 XP_011272309.1 - 0.27 10.3 1.0 0.37 9.9 0.7 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF4407 PF14362.1 XP_011272309.1 - 0.56 9.1 9.8 0.75 8.6 6.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc24 PF08286.6 XP_011272309.1 - 0.71 9.5 21.8 0.33 10.6 5.3 2.5 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 MbeD_MobD PF04899.7 XP_011272309.1 - 1.1 9.1 7.0 1.2 9.1 0.7 2.6 1 1 1 2 2 2 0 MbeD/MobD like Exonuc_VII_L PF02601.10 XP_011272309.1 - 1.7 7.7 14.1 2.2 7.3 9.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit ING PF12998.2 XP_011272309.1 - 2.1 8.6 16.1 0.048 13.9 3.9 2.6 1 1 1 2 2 1 0 Inhibitor of growth proteins N-terminal histone-binding GIDA_assoc_3 PF13932.1 XP_011272309.1 - 3 7.9 8.2 25 5.0 0.2 4.0 2 1 2 4 4 4 0 GidA associated domain 3 Seryl_tRNA_N PF02403.17 XP_011272309.1 - 3.2 7.8 25.2 0.14 12.2 4.9 2.9 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain IncA PF04156.9 XP_011272309.1 - 5.7 6.4 31.1 15 5.1 18.5 2.6 2 1 0 2 2 2 0 IncA protein APG6 PF04111.7 XP_011272309.1 - 6.4 5.7 26.1 9.2 5.2 10.5 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 Bacillus_HBL PF05791.6 XP_011272309.1 - 6.4 6.0 19.6 0.53 9.6 4.7 2.5 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Fib_alpha PF08702.5 XP_011272309.1 - 8.1 6.5 16.4 14 5.7 10.7 1.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Per1 PF04080.8 XP_011272310.1 - 1.1e-90 303.7 15.2 1.9e-90 302.9 10.5 1.4 1 0 0 1 1 1 1 Per1-like Pkinase PF00069.20 XP_011272310.1 - 8.3e-06 25.1 0.0 2.1e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 XP_011272310.1 - 0.018 14.3 0.1 0.037 13.3 0.0 1.4 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 XP_011272310.1 - 0.019 14.6 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Cons_hypoth698 PF03601.9 XP_011272310.1 - 0.74 8.4 2.8 0.4 9.2 0.1 1.7 2 0 0 2 2 2 0 Conserved hypothetical protein 698 Pkinase PF00069.20 XP_011272311.1 - 0.0017 17.5 1.3 0.0019 17.3 0.2 1.7 2 0 0 2 2 2 1 Protein kinase domain Choline_kinase PF01633.15 XP_011272311.1 - 0.0029 17.2 5.1 0.012 15.2 0.3 2.4 2 0 0 2 2 2 2 Choline/ethanolamine kinase APH PF01636.18 XP_011272311.1 - 0.1 12.3 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family HCO3_cotransp PF00955.16 XP_011272312.1 - 1.4e-55 188.9 12.8 4.1e-35 121.4 2.7 2.0 1 1 1 2 2 2 2 HCO3- transporter family BacA PF02673.13 XP_011272312.1 - 0.00098 18.3 1.5 0.026 13.7 0.0 2.6 2 0 0 2 2 2 1 Bacitracin resistance protein BacA PepSY_TM_2 PF13703.1 XP_011272312.1 - 1.2 9.3 9.2 0.48 10.6 0.4 3.8 3 0 0 3 3 3 0 PepSY-associated TM helix ABC_membrane PF00664.18 XP_011272313.1 - 5.6e-54 183.4 9.9 7.5e-54 182.9 6.9 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 XP_011272313.1 - 1.4e-35 122.6 1.2 3.2e-35 121.4 0.0 2.3 3 0 0 3 3 2 1 ABC transporter SMC_N PF02463.14 XP_011272313.1 - 4e-08 32.7 0.7 7.1e-06 25.4 0.5 2.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 XP_011272313.1 - 1.5e-05 25.0 0.0 4.3e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 XP_011272313.1 - 1.8e-05 25.5 0.0 7.4e-05 23.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 XP_011272313.1 - 0.00021 21.4 0.1 0.0015 18.6 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.1 XP_011272313.1 - 0.00027 21.0 13.1 0.0085 16.0 4.9 3.9 2 1 1 3 3 3 1 AAA domain AAA_18 PF13238.1 XP_011272313.1 - 0.00036 20.8 1.4 0.0011 19.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 XP_011272313.1 - 0.00053 19.4 0.0 0.0016 17.9 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_5 PF07728.9 XP_011272313.1 - 0.0011 18.6 0.0 0.0038 16.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.13 XP_011272313.1 - 0.0021 17.5 0.0 0.0049 16.3 0.0 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family DUF258 PF03193.11 XP_011272313.1 - 0.0048 16.0 0.0 0.012 14.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 XP_011272313.1 - 0.0074 15.7 0.4 0.028 13.8 0.2 2.2 1 1 0 1 1 1 1 AAA-like domain AAA_25 PF13481.1 XP_011272313.1 - 0.024 14.0 0.0 0.052 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 XP_011272313.1 - 0.025 14.4 1.6 0.1 12.4 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.1 XP_011272313.1 - 0.049 13.3 0.0 0.17 11.6 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain DUF3987 PF13148.1 XP_011272313.1 - 0.068 11.7 0.0 0.13 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) AAA_33 PF13671.1 XP_011272313.1 - 0.083 12.7 0.0 0.26 11.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 XP_011272313.1 - 2.9 8.1 22.0 71 3.6 13.4 3.7 2 1 0 2 2 2 0 AAA domain Prefoldin PF02996.12 XP_011272315.1 - 0.00018 21.1 0.2 0.00036 20.1 0.2 1.5 1 1 0 1 1 1 1 Prefoldin subunit DUF3896 PF13035.1 XP_011272315.1 - 0.3 11.1 7.3 0.78 9.8 0.3 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3896) AIM24 PF01987.12 XP_011272316.1 - 1.2e-08 34.6 0.0 3.2e-06 26.7 0.0 2.5 2 1 0 2 2 2 2 Mitochondrial biogenesis AIM24 PIG-F PF06699.6 XP_011272317.1 - 1.4e-33 116.4 20.2 4.3e-32 111.6 14.0 2.0 1 1 0 1 1 1 1 GPI biosynthesis protein family Pig-F Ly49 PF08391.5 XP_011272317.1 - 0.078 13.1 1.9 0.09 12.9 0.6 1.7 1 1 0 1 1 1 0 Ly49-like protein, N-terminal region Cytochrom_B_C PF00032.12 XP_011272317.1 - 0.11 12.7 5.1 0.21 11.8 3.3 1.7 1 1 0 1 1 1 0 Cytochrome b(C-terminal)/b6/petD FA_desaturase PF00487.19 XP_011272317.1 - 0.34 10.2 5.7 0.058 12.8 0.8 1.8 1 1 1 2 2 2 0 Fatty acid desaturase ABC2_membrane_3 PF12698.2 XP_011272317.1 - 3.1 6.7 20.0 0.89 8.5 11.7 1.7 1 1 0 1 1 1 0 ABC-2 family transporter protein GATA PF00320.22 XP_011272318.1 - 2.2e-23 81.2 17.9 3.8e-13 48.5 2.2 3.0 3 0 0 3 3 3 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 XP_011272318.1 - 0.00058 19.1 7.2 0.068 12.5 0.2 2.6 2 0 0 2 2 2 2 TFIIB zinc-binding eIF-5_eIF-2B PF01873.12 XP_011272318.1 - 0.014 15.0 0.4 0.014 15.0 0.3 2.4 2 0 0 2 2 2 0 Domain found in IF2B/IF5 zf-CHY PF05495.7 XP_011272318.1 - 1.3 9.2 7.9 4.2 7.6 0.2 2.7 3 0 0 3 3 3 0 CHY zinc finger Kdo PF06293.9 XP_011272319.1 - 0.0012 17.9 0.1 0.0025 16.9 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 XP_011272319.1 - 0.0019 17.3 0.2 0.0036 16.4 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 XP_011272319.1 - 0.16 11.6 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF692 PF05114.8 XP_011272320.1 - 0.024 13.5 0.0 0.025 13.4 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF692) Oxysterol_BP PF01237.13 XP_011272321.1 - 6e-97 324.3 7.6 1e-96 323.5 5.3 1.3 1 0 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.1 XP_011272321.1 - 2.5e-31 107.6 1.0 6.4e-31 106.2 0.7 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 XP_011272321.1 - 0.00035 20.4 2.7 0.00039 20.2 0.4 2.3 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 XP_011272321.1 - 0.12 12.6 10.3 0.68 10.2 4.5 3.7 2 1 0 2 2 2 0 Pleckstrin homology domain Elong_Iki1 PF10483.4 XP_011272322.1 - 7e-78 261.8 5.3 8e-78 261.6 3.6 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 AAA_14 PF13173.1 XP_011272322.1 - 0.0048 16.7 1.0 0.0048 16.7 0.7 2.0 2 1 0 2 2 2 1 AAA domain Rota_NSP4 PF01452.11 XP_011272322.1 - 0.017 14.4 0.9 1.8 7.8 0.0 2.5 2 1 0 2 2 2 0 Rotavirus non structural protein Ribosomal_L18p PF00861.17 XP_011272322.1 - 0.04 14.1 0.0 0.064 13.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal L18p/L5e family Pup PF05639.6 XP_011272323.1 - 1.7 9.1 4.8 0.83 10.2 0.2 2.5 2 0 0 2 2 2 0 Pup-like protein VTC PF09359.5 XP_011272324.1 - 1e-102 342.9 0.1 1.5e-102 342.4 0.1 1.3 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 XP_011272324.1 - 4e-23 82.5 19.2 7e-13 48.9 0.0 4.4 2 2 2 4 4 4 2 SPX domain DUF202 PF02656.10 XP_011272324.1 - 8.4e-08 32.3 6.1 1.5e-07 31.4 3.8 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) MazG PF03819.12 XP_011272324.1 - 0.019 14.8 0.1 0.046 13.6 0.1 1.5 1 0 0 1 1 1 0 MazG nucleotide pyrophosphohydrolase domain PRP1_N PF06424.7 XP_011272324.1 - 1.1 9.5 4.0 0.52 10.6 0.3 2.3 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal RNA_pol_Rpb4 PF03874.11 XP_011272325.1 - 2.6e-26 91.9 8.7 3.3e-26 91.6 6.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 DUF1059 PF06348.6 XP_011272325.1 - 0.0081 15.9 0.4 0.057 13.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1059) TUDOR PF00567.19 XP_011272325.1 - 0.046 13.5 1.0 0.097 12.5 0.2 1.9 1 1 1 2 2 2 0 Tudor domain Ribosomal_L28 PF00830.14 XP_011272325.1 - 0.25 11.2 2.0 0.56 10.0 1.2 1.7 1 1 0 1 1 1 0 Ribosomal L28 family Cpn60_TCP1 PF00118.19 XP_011272326.1 - 8.4e-157 522.6 0.8 9.6e-157 522.4 0.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pkinase PF00069.20 XP_011272327.1 - 1.7e-05 24.1 0.5 8.5e-05 21.8 0.1 2.0 2 0 0 2 2 2 1 Protein kinase domain Kdo PF06293.9 XP_011272327.1 - 0.00096 18.2 0.1 0.002 17.2 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 XP_011272327.1 - 0.024 13.6 0.0 0.041 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase APH PF01636.18 XP_011272327.1 - 0.028 14.1 0.0 0.061 13.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family TGS PF02824.16 XP_011272328.1 - 5e-19 67.8 0.1 1.2e-18 66.7 0.0 1.7 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 XP_011272328.1 - 9.8e-19 67.4 0.1 2.2e-18 66.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 XP_011272328.1 - 1.6e-13 50.2 0.0 2.9e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 XP_011272328.1 - 1.1e-05 25.2 0.5 0.0052 16.6 0.0 2.4 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 XP_011272328.1 - 0.00021 21.7 0.1 0.00048 20.6 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein AIG1 PF04548.11 XP_011272328.1 - 0.0023 17.0 0.1 0.0037 16.3 0.1 1.3 1 0 0 1 1 1 1 AIG1 family MCM PF00493.18 XP_011272328.1 - 0.015 14.0 0.0 0.03 13.1 0.0 1.4 1 0 0 1 1 1 0 MCM2/3/5 family ArgK PF03308.11 XP_011272328.1 - 0.026 13.2 0.5 0.76 8.5 0.0 2.5 3 0 0 3 3 3 0 ArgK protein SRPRB PF09439.5 XP_011272328.1 - 0.054 12.7 0.0 0.093 11.9 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 XP_011272328.1 - 0.095 12.8 0.1 0.88 9.7 0.1 2.4 1 1 1 2 2 2 0 AAA domain DnaJ PF00226.26 XP_011272329.1 - 6.4e-06 25.8 0.0 1.1e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 XP_011272329.1 - 0.00012 21.8 0.0 0.00017 21.3 0.0 1.2 1 0 0 1 1 1 1 Pam16 Ribosomal_L24e PF01246.15 XP_011272330.1 - 3.1e-29 100.6 1.8 3.1e-29 100.6 1.3 1.9 2 0 0 2 2 2 1 Ribosomal protein L24e Astro_capsid PF03115.9 XP_011272330.1 - 0.042 12.1 5.3 0.043 12.0 3.7 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor zf-FCS PF06467.9 XP_011272330.1 - 0.22 11.1 2.6 0.42 10.3 1.8 1.5 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif CDC45 PF02724.9 XP_011272330.1 - 7.4 4.4 15.6 10 3.9 10.8 1.3 1 0 0 1 1 1 0 CDC45-like protein GCD14 PF08704.5 XP_011272331.1 - 0.00015 21.3 0.2 0.003 17.0 0.2 2.2 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit GCD14_N PF14801.1 XP_011272331.1 - 0.0049 16.4 0.0 0.011 15.2 0.0 1.6 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit N-term Ten1 PF12658.2 XP_011272332.1 - 5.6e-05 22.8 0.1 7.3e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Telomere capping, CST complex subunit Imm25 PF15571.1 XP_011272332.1 - 0.081 13.0 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 25 Fungal_trans PF04082.13 XP_011272333.1 - 1e-36 126.1 9.4 4.2e-36 124.1 6.5 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 XP_011272333.1 - 1.4e-10 40.9 10.4 1.4e-10 40.9 7.2 2.4 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ANTH PF07651.11 XP_011272334.1 - 2.2e-57 193.8 0.5 6.4e-57 192.3 0.3 1.8 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 XP_011272334.1 - 2.1e-05 24.3 0.1 6.3e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 ENTH domain HAT PF02184.11 XP_011272334.1 - 0.15 11.8 0.1 0.3 10.8 0.1 1.5 1 0 0 1 1 1 0 HAT (Half-A-TPR) repeat Zn_clus PF00172.13 XP_011272335.1 - 0.00043 20.1 4.4 0.00099 18.9 3.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GST_N_3 PF13417.1 XP_011272336.1 - 1.4e-12 47.6 0.0 2.7e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 XP_011272336.1 - 3.2e-10 39.8 0.0 6.3e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 XP_011272336.1 - 5e-10 39.2 0.0 7.2e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 XP_011272336.1 - 2.3e-07 30.6 0.0 4e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 XP_011272336.1 - 6.1e-07 29.5 0.0 1.1e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 XP_011272336.1 - 2.5e-06 27.9 0.1 3.9e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tachylectin PF14517.1 XP_011272336.1 - 0.021 14.1 0.0 0.03 13.6 0.0 1.1 1 0 0 1 1 1 0 Tachylectin ABC_transp_aux PF09822.4 XP_011272336.1 - 0.025 14.0 0.1 0.28 10.6 0.0 2.1 2 0 0 2 2 2 0 ABC-type uncharacterized transport system GST_C PF00043.20 XP_011272337.1 - 6.1e-10 38.9 0.0 9.3e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 XP_011272337.1 - 2e-09 37.5 0.0 3.3e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 XP_011272337.1 - 1.6e-08 34.3 0.0 3.2e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 XP_011272337.1 - 1.7e-05 25.2 0.0 2.5e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 XP_011272337.1 - 0.0027 17.8 0.0 0.0043 17.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 XP_011272337.1 - 0.0078 16.0 0.0 0.017 14.9 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MFS_1 PF07690.11 XP_011272338.1 - 1.2e-36 126.2 71.4 4.3e-30 104.6 33.0 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 XP_011272338.1 - 1.5e-05 23.7 31.9 7e-05 21.5 8.8 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter DUF983 PF06170.7 XP_011272338.1 - 0.3 11.2 8.7 0.13 12.4 0.5 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF983) Pkinase PF00069.20 XP_011272339.1 - 3.3e-70 236.2 4.1 1.5e-69 234.0 0.0 2.7 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011272339.1 - 1.8e-51 174.6 0.0 4e-51 173.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 XP_011272339.1 - 1.4e-08 34.1 0.1 5.1e-07 28.9 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 XP_011272339.1 - 0.016 14.9 0.0 0.32 10.7 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family PAT1 PF09770.4 XP_011272339.1 - 2.4 6.3 60.6 0.004 15.4 21.4 2.1 1 1 1 2 2 2 0 Topoisomerase II-associated protein PAT1 Sec2p PF06428.6 XP_011272340.1 - 1.2e-24 86.0 11.5 1.2e-24 86.0 8.0 2.7 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p TMF_TATA_bd PF12325.3 XP_011272340.1 - 5.6 6.7 36.8 0.93 9.2 7.4 3.1 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding FH2 PF02181.18 XP_011272341.1 - 2e-84 283.6 10.1 2e-84 283.6 7.0 2.5 3 0 0 3 3 3 1 Formin Homology 2 Domain Drf_GBD PF06371.8 XP_011272341.1 - 1.3e-51 174.6 0.1 1.3e-51 174.6 0.0 3.5 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 XP_011272341.1 - 1.1e-45 155.4 0.0 1.1e-45 155.4 0.0 4.6 4 0 0 4 4 4 2 Diaphanous FH3 Domain TEA PF01285.13 XP_011272342.1 - 1.7e-38 132.9 3.0 3.5e-38 131.8 2.0 1.5 1 0 0 1 1 1 1 TEA/ATTS domain family CBF PF03914.12 XP_011272343.1 - 3.8e-43 146.7 0.2 3.8e-43 146.7 0.1 3.7 4 0 0 4 4 4 1 CBF/Mak21 family UQ_con PF00179.21 XP_011272344.1 - 1.6e-51 173.3 0.0 1.8e-51 173.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 XP_011272344.1 - 5.8e-05 22.8 0.0 7.1e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 XP_011272344.1 - 0.00027 20.7 0.0 0.00033 20.5 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 XP_011272344.1 - 0.014 15.0 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 UEV domain HLH PF00010.21 XP_011272345.1 - 2.7e-16 59.0 0.1 6.7e-16 57.7 0.1 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PRKCSH PF07915.8 XP_011272346.1 - 0.0079 16.9 0.7 0.0079 16.9 0.5 3.1 3 0 0 3 3 3 1 Glucosidase II beta subunit-like protein AAA PF00004.24 XP_011272347.1 - 2.4e-49 166.9 0.0 9.1e-38 129.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 XP_011272347.1 - 9.7e-12 44.6 0.0 6.7e-11 41.9 0.0 2.3 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain CDC48_2 PF02933.12 XP_011272347.1 - 7.1e-09 35.1 1.1 2.7e-08 33.3 0.1 2.2 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.1 XP_011272347.1 - 1.2e-08 35.2 0.1 0.00076 19.6 0.1 3.4 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.1 XP_011272347.1 - 6.3e-08 32.2 0.3 0.0022 17.6 0.1 2.6 2 0 0 2 2 2 2 Part of AAA domain Mg_chelatase PF01078.16 XP_011272347.1 - 1.7e-07 30.5 0.1 0.0005 19.2 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 XP_011272347.1 - 3.4e-07 29.3 0.1 0.016 13.9 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_33 PF13671.1 XP_011272347.1 - 4.7e-07 29.7 0.0 0.014 15.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 XP_011272347.1 - 1.6e-06 27.6 0.2 0.037 13.4 0.0 2.6 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_17 PF13207.1 XP_011272347.1 - 2.8e-06 28.1 0.0 0.046 14.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 XP_011272347.1 - 3.7e-06 26.7 0.0 0.0016 18.1 0.0 3.2 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) PhoH PF02562.11 XP_011272347.1 - 4.2e-06 26.1 0.0 0.0076 15.5 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein AAA_16 PF13191.1 XP_011272347.1 - 1.1e-05 25.5 0.0 0.069 13.1 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain ABC_tran PF00005.22 XP_011272347.1 - 1.6e-05 25.1 1.1 0.019 15.2 0.0 3.0 3 0 0 3 3 3 1 ABC transporter AAA_2 PF07724.9 XP_011272347.1 - 3.6e-05 23.7 0.0 0.0015 18.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) NACHT PF05729.7 XP_011272347.1 - 5e-05 23.0 1.0 0.081 12.5 0.0 3.6 4 0 0 4 4 3 1 NACHT domain AAA_18 PF13238.1 XP_011272347.1 - 7.1e-05 23.1 0.0 0.015 15.5 0.0 3.0 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.17 XP_011272347.1 - 0.00019 21.5 0.0 0.38 10.9 0.0 2.9 2 0 0 2 2 2 1 RNA helicase RuvB_N PF05496.7 XP_011272347.1 - 0.00044 19.3 0.1 0.17 10.9 0.0 2.7 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_23 PF13476.1 XP_011272347.1 - 0.0013 19.0 1.4 1.3 9.2 0.0 2.8 3 1 0 3 3 2 1 AAA domain NB-ARC PF00931.17 XP_011272347.1 - 0.0021 16.9 0.0 0.26 10.1 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain AAA_30 PF13604.1 XP_011272347.1 - 0.0021 17.6 0.1 0.88 9.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.21 XP_011272347.1 - 0.0028 17.1 0.0 2.1 7.8 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain DUF2075 PF09848.4 XP_011272347.1 - 0.0032 16.5 0.0 0.24 10.3 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) UPF0079 PF02367.12 XP_011272347.1 - 0.0034 17.0 0.0 4.2 7.0 0.0 3.3 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 DEAD PF00270.24 XP_011272347.1 - 0.0037 16.7 0.6 17 4.8 0.1 3.9 2 2 2 4 4 4 0 DEAD/DEAH box helicase Zeta_toxin PF06414.7 XP_011272347.1 - 0.0042 16.1 0.1 2.1 7.3 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_24 PF13479.1 XP_011272347.1 - 0.0066 16.0 0.2 3 7.3 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 XP_011272347.1 - 0.014 15.3 0.0 2.9 7.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.12 XP_011272347.1 - 0.022 13.6 0.0 3.2 6.5 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.1 XP_011272347.1 - 0.03 14.3 0.2 10 6.1 0.0 3.2 2 1 0 2 2 2 0 Sigma-54 interaction domain CTP-dep_RFKase PF01982.11 XP_011272347.1 - 0.033 13.7 0.0 0.085 12.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF120 AAA_11 PF13086.1 XP_011272347.1 - 0.051 13.1 0.1 3.1 7.2 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.1 XP_011272347.1 - 0.054 12.9 6.5 5.8 6.2 0.6 3.5 2 2 0 3 3 3 0 AAA domain AAA_3 PF07726.6 XP_011272347.1 - 0.09 12.3 0.0 0.45 10.1 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 XP_011272347.1 - 0.092 11.8 1.0 0.45 9.5 0.1 2.3 2 1 0 3 3 2 0 KaiC AAA_29 PF13555.1 XP_011272347.1 - 0.11 11.9 0.2 5.4 6.6 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Torsin PF06309.6 XP_011272347.1 - 0.16 11.8 0.0 4.5 7.1 0.0 2.8 2 0 0 2 2 2 0 Torsin SET PF00856.23 XP_011272348.1 - 4.2e-09 36.9 0.0 4.2e-09 36.9 0.0 3.0 2 1 0 2 2 2 1 SET domain GLTP PF08718.6 XP_011272349.1 - 3.1e-37 127.8 3.6 6.1e-37 126.9 0.1 3.3 3 0 0 3 3 3 1 Glycolipid transfer protein (GLTP) PCI PF01399.22 XP_011272349.1 - 1.3e-08 35.0 1.3 5.2e-08 33.1 0.1 2.8 2 1 0 2 2 2 1 PCI domain Recep_L_domain PF01030.19 XP_011272350.1 - 4.6e-07 29.8 13.4 0.027 14.4 0.1 5.1 1 1 4 5 5 5 3 Receptor L domain LRR_5 PF13306.1 XP_011272350.1 - 2.1e-05 24.2 6.9 0.031 13.9 0.5 2.9 1 1 0 2 2 2 2 Leucine rich repeats (6 copies) CHZ PF09649.5 XP_011272350.1 - 2 7.7 4.8 0.83 8.9 0.2 2.6 3 0 0 3 3 3 0 Histone chaperone domain CHZ Viral_cys_rich PF08008.7 XP_011272351.1 - 0.25 10.9 3.6 0.12 11.9 1.0 1.6 2 0 0 2 2 2 0 Viral cysteine rich PADR1 PF08063.7 XP_011272353.1 - 0.017 14.4 0.5 1.4 8.4 0.0 2.2 2 0 0 2 2 2 0 PADR1 (NUC008) domain zinc_ribbon_4 PF13717.1 XP_011272353.1 - 0.019 14.6 0.6 1.5 8.6 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.2 XP_011272353.1 - 0.021 14.6 2.3 0.071 12.9 1.7 1.7 1 1 0 1 1 1 0 Transposase zinc-ribbon domain zinc_ribbon_5 PF13719.1 XP_011272353.1 - 0.033 13.7 0.7 2 8.0 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-LITAF-like PF10601.4 XP_011272353.1 - 0.065 13.0 1.2 0.15 11.8 0.8 1.6 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain zf-CHY PF05495.7 XP_011272353.1 - 0.077 13.1 0.6 0.14 12.2 0.4 1.5 1 1 0 1 1 1 0 CHY zinc finger Cytochrome_C7 PF14522.1 XP_011272353.1 - 0.087 12.4 1.2 0.23 11.0 0.9 1.7 1 1 0 1 1 1 0 Cytochrome c7 PSCyt2 PF07583.6 XP_011272353.1 - 0.1 12.0 0.2 0.16 11.4 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1549) Zn-ribbon_8 PF09723.5 XP_011272353.1 - 0.11 12.5 0.5 0.69 9.9 0.1 2.0 2 0 0 2 2 2 0 Zinc ribbon domain HypA PF01155.14 XP_011272353.1 - 0.11 12.1 0.2 1.2 8.8 0.0 1.9 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Elf1 PF05129.8 XP_011272353.1 - 0.11 12.1 0.9 0.25 11.0 0.6 1.5 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like Rubredoxin PF00301.15 XP_011272353.1 - 0.12 12.2 0.6 10 6.0 0.0 2.2 2 0 0 2 2 2 0 Rubredoxin zf-ribbon_3 PF13248.1 XP_011272353.1 - 0.14 11.4 2.1 0.23 10.7 0.4 1.9 2 0 0 2 2 2 0 zinc-ribbon domain CcmH PF03918.9 XP_011272353.1 - 7.7 5.5 5.7 1.4 7.8 0.3 2.1 1 1 1 2 2 2 0 Cytochrome C biogenesis protein SR-25 PF10500.4 XP_011272354.1 - 6.9 6.0 20.0 1.9 7.8 5.7 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Dmrt1 PF12374.3 XP_011272354.1 - 8.4 6.8 17.8 0.31 11.3 2.3 3.2 2 1 1 3 3 3 0 Double-sex mab3 related transcription factor 1 AMPKBI PF04739.10 XP_011272355.1 - 5.8e-27 93.4 5.6 5.8e-27 93.4 3.9 2.8 2 1 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interation domain Zn_clus PF00172.13 XP_011272357.1 - 4.3e-08 32.9 9.1 8e-08 32.0 6.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 XP_011272357.1 - 0.47 10.6 9.5 3 8.0 1.5 2.4 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region Fungal_trans PF04082.13 XP_011272357.1 - 1.6 7.5 24.6 0.055 12.3 2.2 4.4 4 2 1 5 5 5 0 Fungal specific transcription factor domain DOPA_dioxygen PF08883.6 XP_011272358.1 - 1.9e-25 88.9 0.2 2.3e-25 88.6 0.2 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family DUF3271 PF11675.3 XP_011272358.1 - 0.0063 15.6 1.0 0.0091 15.1 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3271) Sugar_tr PF00083.19 XP_011272359.1 - 9.4e-26 90.3 30.9 3.3e-17 62.1 7.2 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 XP_011272359.1 - 6e-18 64.6 43.3 1.4e-10 40.4 20.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily NfeD PF01957.13 XP_011272359.1 - 2.6 8.1 7.3 2.2 8.4 0.0 3.4 3 0 0 3 3 3 0 NfeD-like C-terminal, partner-binding DUF885 PF05960.6 XP_011272360.1 - 0.052 12.6 0.0 0.069 12.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) DER1 PF04511.10 XP_011272362.1 - 2e-18 66.6 8.6 2.6e-18 66.2 6.0 1.1 1 0 0 1 1 1 1 Der1-like family RFX_DNA_binding PF02257.10 XP_011272363.1 - 2.1e-13 50.2 0.4 6.4e-13 48.6 0.3 1.9 1 1 0 1 1 1 1 RFX DNA-binding domain Carn_acyltransf PF00755.15 XP_011272364.1 - 9.9e-159 529.1 0.2 1.1e-158 528.9 0.1 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase SNF2_N PF00176.18 XP_011272365.1 - 6.6e-76 254.9 1.3 1.3e-75 253.9 0.9 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 XP_011272365.1 - 3.1e-15 55.8 0.0 1.3e-14 53.7 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HSA PF07529.8 XP_011272365.1 - 9e-13 47.8 4.7 9e-13 47.8 3.3 3.6 3 0 0 3 3 3 1 HSA DEAD PF00270.24 XP_011272365.1 - 6e-07 29.1 0.0 3e-06 26.8 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase RRM_1 PF00076.17 XP_011272366.1 - 2.2e-16 59.2 2.0 4.8e-09 35.7 0.1 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 XP_011272366.1 - 4.8e-10 39.2 0.0 1.8e-05 24.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 XP_011272366.1 - 0.022 14.5 0.0 0.49 10.2 0.0 2.6 2 0 0 2 2 2 0 RNA binding motif NDUF_B8 PF05821.6 XP_011272367.1 - 5.6e-12 45.6 1.3 6.9e-12 45.3 0.9 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) RRM_1 PF00076.17 XP_011272368.1 - 3.2e-42 141.9 0.0 7.4e-17 60.7 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 XP_011272368.1 - 5.2e-24 84.0 0.0 2.4e-08 33.8 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 XP_011272368.1 - 2.8e-22 78.3 0.0 3.9e-10 39.4 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 XP_011272368.1 - 0.0016 18.2 0.0 0.0071 16.1 0.0 2.1 2 0 0 2 2 2 1 RNA binding motif MFS_1 PF07690.11 XP_011272369.1 - 7e-34 117.0 34.8 7e-34 117.0 24.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Myc_target_1 PF15179.1 XP_011272369.1 - 0.08 12.5 0.4 0.98 8.9 0.7 2.1 2 0 0 2 2 2 0 Myc target protein 1 DUF4381 PF14316.1 XP_011272369.1 - 0.32 11.0 0.8 40 4.2 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) V-ATPase_C PF03223.10 XP_011272370.1 - 1.1e-112 376.6 9.0 1.3e-112 376.4 6.2 1.0 1 0 0 1 1 1 1 V-ATPase subunit C Kinesin PF00225.18 XP_011272371.1 - 9e-110 366.5 5.5 9e-110 366.5 3.8 2.4 3 1 0 3 3 3 1 Kinesin motor domain NIF PF03031.13 XP_011272372.1 - 2.5e-54 183.2 0.5 2.5e-54 183.2 0.4 1.9 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase adh_short PF00106.20 XP_011272373.1 - 2.5e-26 92.5 0.1 3e-26 92.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 XP_011272373.1 - 6.7e-21 75.1 0.0 8.4e-21 74.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 XP_011272373.1 - 2.2e-14 53.5 0.0 3.3e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 XP_011272373.1 - 0.0033 16.3 0.0 0.0054 15.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein LNS2 PF08235.8 XP_011272373.1 - 0.031 13.8 0.0 0.049 13.1 0.0 1.4 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) NAD_binding_10 PF13460.1 XP_011272373.1 - 0.058 13.3 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding zinc_ribbon_6 PF14599.1 XP_011272374.1 - 2.2e-24 85.0 5.4 2.2e-24 85.0 3.8 3.6 3 1 1 4 4 4 1 Zinc-ribbon zf-CHY PF05495.7 XP_011272374.1 - 7.5e-12 45.2 21.7 7.5e-12 45.2 15.0 4.7 3 1 1 4 4 4 1 CHY zinc finger zf-RING_2 PF13639.1 XP_011272374.1 - 3.5e-08 33.1 8.1 3.5e-08 33.1 5.6 4.8 4 2 1 5 5 5 1 Ring finger domain zf-C3HC4_2 PF13923.1 XP_011272374.1 - 1.9e-06 27.7 8.2 1.9e-06 27.7 5.7 5.0 5 1 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 XP_011272374.1 - 0.00015 21.4 10.5 0.00015 21.4 7.3 6.3 3 2 3 6 6 6 1 zinc-RING finger domain DivIC PF04977.10 XP_011272375.1 - 0.0049 16.3 2.3 0.0049 16.3 1.6 6.3 4 1 3 7 7 7 2 Septum formation initiator Cep57_CLD_2 PF14197.1 XP_011272375.1 - 0.041 13.8 1.5 0.041 13.8 1.0 5.7 4 1 1 5 5 5 0 Centrosome localisation domain of PPC89 AAA_13 PF13166.1 XP_011272375.1 - 0.63 8.4 47.1 3.7 5.8 14.3 2.1 1 1 1 2 2 2 0 AAA domain CCDC155 PF14662.1 XP_011272375.1 - 7.2 6.1 46.5 0.04 13.5 8.2 4.0 1 1 3 4 4 4 0 Coiled-coil region of CCDC155 Nup54 PF13874.1 XP_011272375.1 - 9.1 5.9 22.8 0.14 11.8 2.0 3.9 2 1 1 3 3 3 0 Nucleoporin complex subunit 54 Perilipin PF03036.11 XP_011272376.1 - 0.042 12.6 9.6 0.06 12.1 6.6 1.2 1 0 0 1 1 1 0 Perilipin family GAGA_bind PF06217.7 XP_011272376.1 - 0.059 13.3 20.0 0.071 13.0 13.8 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Reo_sigmaC PF04582.7 XP_011272376.1 - 1.3 8.1 7.1 4.7 6.2 0.6 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF2841 PF11001.3 XP_011272377.1 - 1.1e-38 131.9 1.6 2.3e-38 130.8 1.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) F-box-like PF12937.2 XP_011272378.1 - 0.0037 16.9 0.2 0.0093 15.6 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 XP_011272378.1 - 0.009 15.6 0.5 0.047 13.3 0.8 1.8 2 0 0 2 2 2 1 F-box domain LtrA PF06772.6 XP_011272380.1 - 1.8e-21 76.4 10.7 2.4e-21 76.0 7.4 1.1 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) SUKH-3 PF14433.1 XP_011272380.1 - 0.075 12.8 0.1 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 SUKH-3 immunity protein adh_short_C2 PF13561.1 XP_011272382.1 - 3.3e-24 85.9 0.0 4e-24 85.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 XP_011272382.1 - 2.1e-22 79.7 0.0 2.8e-22 79.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 XP_011272382.1 - 1.1e-11 44.7 0.0 1.3e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 KR domain Pab87_oct PF13969.1 XP_011272382.1 - 0.016 15.3 0.0 0.034 14.2 0.0 1.6 1 0 0 1 1 1 0 Pab87 octamerisation domain LtrA PF06772.6 XP_011272383.1 - 3e-21 75.7 12.3 4.6e-21 75.1 8.5 1.2 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) DUF1772 PF08592.6 XP_011272383.1 - 0.69 9.6 5.0 6.6 6.4 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) Bax1-I PF01027.15 XP_011272384.1 - 2e-51 174.5 27.4 2.3e-51 174.3 19.0 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Spore_YhaL PF14147.1 XP_011272384.1 - 0.26 10.7 2.4 0.29 10.5 0.1 2.3 2 0 0 2 2 2 0 Sporulation protein YhaL DUF1011 PF06237.7 XP_011272384.1 - 1.8 8.4 7.0 8.1 6.3 1.1 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF1011) PetL PF05115.9 XP_011272384.1 - 3.7 7.5 11.7 0.12 12.3 0.6 3.0 3 0 0 3 3 3 0 Cytochrome B6-F complex subunit VI (PetL) NAD_binding_10 PF13460.1 XP_011272385.1 - 1.2e-14 54.7 0.0 1.6e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 XP_011272385.1 - 5.1e-12 45.7 0.0 1e-11 44.7 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 XP_011272385.1 - 2.6e-10 39.4 0.0 3.3e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 XP_011272385.1 - 2.3e-08 33.5 0.1 3.9e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 XP_011272385.1 - 2.3e-06 26.7 0.1 3e-05 23.0 0.1 2.2 1 1 0 1 1 1 1 RmlD substrate binding domain TrkA_N PF02254.13 XP_011272385.1 - 3.8e-06 26.8 0.1 2.6e-05 24.2 0.1 2.1 2 0 0 2 2 2 1 TrkA-N domain NAD_binding_4 PF07993.7 XP_011272385.1 - 9.4e-05 21.4 0.2 0.00057 18.8 0.1 2.4 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 XP_011272385.1 - 0.00023 21.1 0.0 0.00055 19.9 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase Saccharop_dh PF03435.13 XP_011272385.1 - 0.0018 17.3 0.0 0.0033 16.4 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase Pyr_redox PF00070.22 XP_011272385.1 - 0.003 17.9 0.0 0.54 10.7 0.1 3.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.10 XP_011272385.1 - 0.013 15.2 0.0 0.027 14.2 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase KR PF08659.5 XP_011272385.1 - 0.015 14.9 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 KR domain 2-Hacid_dh_C PF02826.14 XP_011272385.1 - 0.024 13.8 0.0 0.039 13.0 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 XP_011272385.1 - 0.032 13.6 0.0 0.072 12.5 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Polysacc_synt_2 PF02719.10 XP_011272385.1 - 0.047 12.5 0.0 0.086 11.7 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.19 XP_011272385.1 - 0.088 13.1 0.2 0.2 11.9 0.0 1.6 2 0 0 2 2 1 0 Semialdehyde dehydrogenase, NAD binding domain Synaptobrevin PF00957.16 XP_011272386.1 - 6.1e-23 80.2 6.2 9.9e-23 79.5 4.3 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 XP_011272386.1 - 0.0021 17.5 0.1 0.0037 16.7 0.1 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain CLTH PF10607.4 XP_011272386.1 - 5.4 6.7 8.1 50 3.5 5.6 2.3 1 1 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain MSG PF02349.10 XP_011272387.1 - 0.14 12.1 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Major surface glycoprotein CBFD_NFYB_HMF PF00808.18 XP_011272388.1 - 1.2e-05 25.2 0.0 2.7e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 XP_011272388.1 - 0.093 12.8 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 DUF1510 PF07423.6 XP_011272388.1 - 0.18 11.1 17.4 0.23 10.8 12.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) NOA36 PF06524.7 XP_011272388.1 - 1.6 7.8 8.5 2.1 7.5 5.9 1.1 1 0 0 1 1 1 0 NOA36 protein Hid1 PF12722.2 XP_011272388.1 - 7.9 4.0 12.6 8 3.9 8.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CBFD_NFYB_HMF PF00808.18 XP_011272389.1 - 3.2e-26 91.1 0.1 4.7e-26 90.6 0.1 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 XP_011272389.1 - 2.9e-06 27.3 0.0 4.8e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID_20kDa PF03847.8 XP_011272389.1 - 0.17 12.1 1.5 0.41 10.9 0.0 2.3 3 0 0 3 3 3 0 Transcription initiation factor TFIID subunit A Lon_C PF05362.8 XP_011272390.1 - 9.9e-65 217.6 0.0 2.2e-64 216.5 0.0 1.6 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 XP_011272390.1 - 3.9e-35 121.3 2.4 3.9e-35 121.3 1.7 3.0 3 0 0 3 3 3 1 ATP-dependent protease La (LON) domain AAA PF00004.24 XP_011272390.1 - 2.6e-24 85.8 0.0 1.3e-23 83.6 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 XP_011272390.1 - 1.4e-07 31.3 0.0 6.4e-07 29.1 0.0 2.3 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 XP_011272390.1 - 6.2e-07 28.9 0.0 1.4e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.9 XP_011272390.1 - 1.3e-06 28.4 0.0 7.8e-06 25.9 0.0 2.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 XP_011272390.1 - 2.6e-05 25.0 0.8 0.00021 22.1 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.1 XP_011272390.1 - 4.2e-05 23.6 1.9 0.00071 19.7 0.0 3.6 2 2 0 2 2 2 1 AAA domain AAA_PrkA PF08298.6 XP_011272390.1 - 7.7e-05 21.5 0.3 0.0002 20.1 0.0 1.8 2 0 0 2 2 2 1 PrkA AAA domain AAA_16 PF13191.1 XP_011272390.1 - 0.00087 19.3 0.6 0.0072 16.3 0.0 2.8 3 1 0 3 3 3 1 AAA ATPase domain AAA_14 PF13173.1 XP_011272390.1 - 0.0011 18.9 0.2 0.0071 16.2 0.0 2.6 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 XP_011272390.1 - 0.0014 17.7 0.0 0.0047 16.0 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus ATP-synt_ab PF00006.20 XP_011272390.1 - 0.0034 16.9 0.0 0.0065 15.9 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_18 PF13238.1 XP_011272390.1 - 0.0057 16.9 0.0 0.0057 16.9 0.0 4.9 4 1 0 4 4 4 1 AAA domain AAA_10 PF12846.2 XP_011272390.1 - 0.016 14.6 0.1 0.044 13.2 0.0 1.9 2 0 0 2 2 1 0 AAA-like domain DUF258 PF03193.11 XP_011272390.1 - 0.017 14.3 0.0 0.041 13.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 XP_011272390.1 - 0.021 14.9 0.1 0.1 12.7 0.0 2.3 2 0 0 2 2 1 0 RNA helicase AAA_3 PF07726.6 XP_011272390.1 - 0.024 14.2 0.0 0.057 13.0 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SKI PF01202.17 XP_011272390.1 - 0.039 13.8 0.0 0.039 13.8 0.0 2.7 2 0 0 2 2 1 0 Shikimate kinase IstB_IS21 PF01695.12 XP_011272390.1 - 0.042 13.2 0.0 0.098 12.0 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 XP_011272390.1 - 0.07 12.5 0.0 0.18 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 XP_011272390.1 - 0.11 12.4 0.5 0.29 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 XP_011272390.1 - 0.37 11.0 0.0 0.37 11.0 0.0 3.3 3 1 0 3 3 3 0 ABC transporter Aldedh PF00171.17 XP_011272391.1 - 2.2e-158 527.4 0.0 2.5e-158 527.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 XP_011272391.1 - 0.07 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) Mem_trans PF03547.13 XP_011272392.1 - 6.6e-59 199.1 13.8 1.1e-58 198.3 9.6 1.3 1 1 0 1 1 1 1 Membrane transport protein FeoB_C PF07664.7 XP_011272392.1 - 3 7.3 6.7 0.42 10.0 0.4 2.9 3 0 0 3 3 3 0 Ferrous iron transport protein B C terminus Gp_dh_C PF02800.15 XP_011272393.1 - 5.2e-71 237.1 0.0 7.9e-71 236.5 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 XP_011272393.1 - 3.1e-60 202.5 0.0 4.9e-60 201.8 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 XP_011272393.1 - 0.015 14.4 0.1 0.053 12.6 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DapB_N PF01113.15 XP_011272393.1 - 0.022 14.6 0.2 0.13 12.2 0.0 2.4 3 0 0 3 3 3 0 Dihydrodipicolinate reductase, N-terminus ADH_zinc_N PF00107.21 XP_011272393.1 - 0.03 13.8 0.0 0.078 12.5 0.0 1.7 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Aminotran_3 PF00202.16 XP_011272394.1 - 2.5e-103 345.4 0.0 3e-103 345.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 XP_011272394.1 - 0.012 14.7 0.0 0.026 13.6 0.0 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase Aminotran_1_2 PF00155.16 XP_011272394.1 - 0.13 11.2 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II RNR_inhib PF08591.5 XP_011272395.1 - 0.0011 19.7 0.1 0.0062 17.4 0.1 2.0 1 1 0 1 1 1 1 Ribonucleotide reductase inhibitor Med11 PF10280.4 XP_011272395.1 - 0.088 12.8 0.0 0.12 12.4 0.0 1.4 1 1 0 1 1 1 0 Mediator complex protein Hid1 PF12722.2 XP_011272396.1 - 1.1e-178 595.7 72.0 1.5e-151 506.0 32.6 2.1 1 1 1 2 2 2 2 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 XP_011272396.1 - 2e-34 118.7 9.1 3.4e-34 118.0 6.3 1.3 1 1 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein CobT PF06213.7 XP_011272396.1 - 1.3 8.0 6.4 2.1 7.4 4.5 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CNH PF00780.17 XP_011272397.1 - 3.1e-27 95.6 2.2 5.9e-27 94.7 1.5 1.4 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.1 XP_011272397.1 - 6.3e-07 29.4 0.6 0.00045 20.1 0.4 3.0 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 XP_011272397.1 - 1.2e-06 28.6 0.3 1.2e-06 28.6 0.2 3.1 3 0 0 3 3 3 1 PH domain IMPDH PF00478.20 XP_011272398.1 - 2.6e-29 102.2 0.0 3.1e-29 101.9 0.0 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 XP_011272398.1 - 0.028 14.1 0.0 0.086 12.6 0.0 1.9 1 0 0 1 1 1 0 CBS domain NMO PF03060.10 XP_011272398.1 - 0.069 12.2 0.0 0.079 12.0 0.0 1.1 1 0 0 1 1 1 0 Nitronate monooxygenase IMPDH PF00478.20 XP_011272399.1 - 2.7e-111 371.8 3.0 3.3e-111 371.5 2.1 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 XP_011272399.1 - 7.7e-10 38.4 0.2 2.1e-07 30.5 0.0 2.4 2 0 0 2 2 2 1 CBS domain FMN_dh PF01070.13 XP_011272399.1 - 1.9e-06 26.9 1.1 5.7e-06 25.4 0.8 1.7 1 1 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.10 XP_011272399.1 - 2.3e-05 23.7 6.1 2.7e-05 23.4 3.5 1.6 1 1 0 2 2 2 1 Nitronate monooxygenase His_biosynth PF00977.16 XP_011272399.1 - 5.9e-05 22.4 1.5 0.00042 19.6 1.0 2.1 1 1 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.9 XP_011272399.1 - 0.00024 20.2 2.5 0.00098 18.2 0.5 2.1 1 1 1 2 2 2 1 Thiazole biosynthesis protein ThiG NanE PF04131.9 XP_011272399.1 - 0.0008 18.4 0.3 0.0017 17.3 0.2 1.5 1 0 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase Aldolase PF01081.14 XP_011272399.1 - 0.0017 17.5 0.1 0.0042 16.2 0.1 1.6 1 0 0 1 1 1 1 KDPG and KHG aldolase Response_reg PF00072.19 XP_011272399.1 - 0.0099 15.8 0.2 0.12 12.3 0.0 2.2 2 0 0 2 2 2 1 Response regulator receiver domain EAL PF00563.15 XP_011272399.1 - 0.018 14.5 0.1 0.098 12.1 0.0 1.9 2 0 0 2 2 2 0 EAL domain DUF1273 PF06908.6 XP_011272399.1 - 0.028 14.0 0.0 0.049 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1273) PK PF00224.16 XP_011272399.1 - 0.033 12.8 0.2 0.086 11.4 0.0 1.8 2 0 0 2 2 2 0 Pyruvate kinase, barrel domain B12-binding PF02310.14 XP_011272399.1 - 0.069 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 B12 binding domain PcrB PF01884.12 XP_011272399.1 - 0.11 11.6 4.8 3.1 6.9 0.1 3.6 2 1 2 4 4 4 0 PcrB family DHO_dh PF01180.16 XP_011272399.1 - 3.8 6.3 7.1 11 4.8 0.5 2.6 3 0 0 3 3 3 0 Dihydroorotate dehydrogenase Ribosomal_S3Ae PF01015.13 XP_011272400.1 - 6.2e-77 257.3 5.7 7.3e-77 257.1 3.9 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family CAT_RBD PF03123.10 XP_011272400.1 - 0.048 13.3 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 CAT RNA binding domain Ras PF00071.17 XP_011272401.1 - 8.2e-25 87.0 1.6 9.4e-25 86.8 1.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 XP_011272401.1 - 3.6e-12 46.8 0.5 2e-11 44.4 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 XP_011272401.1 - 8.4e-07 28.3 0.4 9.5e-07 28.2 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 XP_011272401.1 - 0.0085 15.5 0.1 0.01 15.2 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain G-alpha PF00503.15 XP_011272401.1 - 0.065 11.9 6.4 1.7 7.2 4.4 2.1 1 1 0 1 1 1 0 G-protein alpha subunit AAA PF00004.24 XP_011272402.1 - 1e-18 67.8 0.0 2.2e-18 66.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 XP_011272402.1 - 3.1e-11 43.5 0.0 1.8e-09 37.8 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain BAH PF01426.13 XP_011272402.1 - 4.8e-10 39.2 0.1 1.3e-09 37.8 0.1 1.8 1 0 0 1 1 1 1 BAH domain AAA_22 PF13401.1 XP_011272402.1 - 3.7e-09 36.8 0.0 8.2e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 XP_011272402.1 - 7.6e-06 25.7 0.3 3.1e-05 23.8 0.0 2.2 2 0 0 2 2 2 1 Archaeal ATPase AAA_17 PF13207.1 XP_011272402.1 - 7.7e-05 23.5 0.3 0.031 15.0 0.0 3.4 3 1 0 3 3 3 1 AAA domain AAA_19 PF13245.1 XP_011272402.1 - 0.0022 17.6 0.0 0.006 16.3 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 XP_011272402.1 - 0.0026 18.0 0.0 0.013 15.8 0.0 2.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 XP_011272402.1 - 0.0028 17.2 0.0 0.0077 15.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.9 XP_011272402.1 - 0.0029 16.6 0.1 0.42 9.5 0.0 2.4 1 1 1 2 2 2 1 KAP family P-loop domain NACHT PF05729.7 XP_011272402.1 - 0.0036 16.9 0.0 0.011 15.3 0.0 1.8 1 1 0 1 1 1 1 NACHT domain AAA_35 PF14516.1 XP_011272402.1 - 0.0047 15.6 0.1 0.028 13.0 0.0 2.2 1 1 0 1 1 1 1 AAA-like domain NTPase_1 PF03266.10 XP_011272402.1 - 0.0051 16.5 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 NTPase RNA_helicase PF00910.17 XP_011272402.1 - 0.008 16.3 0.1 0.035 14.2 0.1 2.2 1 1 0 1 1 1 1 RNA helicase Nnf1 PF03980.9 XP_011272402.1 - 0.04 13.9 0.5 0.93 9.5 0.0 2.7 2 0 0 2 2 2 0 Nnf1 AAA_28 PF13521.1 XP_011272402.1 - 0.095 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain RRN3 PF05327.6 XP_011272402.1 - 5.5 4.9 8.8 8.7 4.3 6.1 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SUR7 PF06687.7 XP_011272403.1 - 1.1e-18 67.5 7.9 1.6e-18 67.0 5.5 1.2 1 0 0 1 1 1 1 SUR7/PalI family DUF4131 PF13567.1 XP_011272403.1 - 0.12 11.7 3.6 0.62 9.4 1.4 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) Chitin_bind_1 PF00187.14 XP_011272403.1 - 0.13 12.2 0.2 0.5 10.3 0.0 1.9 2 0 0 2 2 2 0 Chitin recognition protein DLL_N PF12413.3 XP_011272403.1 - 3.5 8.7 7.7 0.72 10.9 2.9 1.7 2 0 0 2 2 2 0 Homeobox protein distal-less-like N terminal fn2 PF00040.14 XP_011272403.1 - 4 7.5 5.3 0.34 10.9 0.2 1.9 2 0 0 2 2 2 0 Fibronectin type II domain DUF2975 PF11188.3 XP_011272403.1 - 4.7 6.9 7.4 2.5 7.8 3.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) AA_permease_2 PF13520.1 XP_011272405.1 - 7.9e-52 176.2 50.8 1e-51 175.8 35.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 XP_011272405.1 - 2.3e-16 59.1 44.0 4.6e-16 58.2 30.5 1.4 1 1 0 1 1 1 1 Amino acid permease DUF3493 PF11998.3 XP_011272405.1 - 0.094 12.6 1.8 1.2 9.0 1.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3493) AA_permease_2 PF13520.1 XP_011272406.1 - 8e-56 189.3 50.6 1e-55 189.0 35.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 XP_011272406.1 - 8.1e-20 70.6 44.5 1.1e-19 70.1 30.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 XP_011272407.1 - 1.8e-56 191.4 54.1 2.3e-56 191.1 37.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 XP_011272407.1 - 4.9e-19 68.0 42.6 8e-19 67.3 29.6 1.3 1 1 0 1 1 1 1 Amino acid permease Sugar_tr PF00083.19 XP_011272408.1 - 3.6e-100 335.6 23.0 4.6e-100 335.3 15.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 XP_011272408.1 - 8.3e-25 87.2 25.9 1.4e-16 60.2 5.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Herpes_pp38 PF04846.8 XP_011272408.1 - 0.0077 15.5 0.5 0.024 13.9 0.3 1.8 1 0 0 1 1 1 1 Herpesvirus pp38 phosphoprotein Mif2_N PF15624.1 XP_011272408.1 - 0.075 13.6 2.0 0.11 13.0 1.4 1.2 1 0 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal SET PF00856.23 XP_011272409.1 - 1.3e-06 28.8 0.0 2.1e-06 28.1 0.0 1.6 1 1 0 1 1 1 1 SET domain SUR7 PF06687.7 XP_011272410.1 - 4.9e-44 150.4 6.5 6.2e-44 150.1 4.5 1.1 1 0 0 1 1 1 1 SUR7/PalI family Amastin PF07344.6 XP_011272410.1 - 0.00079 19.0 4.4 0.00079 19.0 3.1 2.1 2 0 0 2 2 2 1 Amastin surface glycoprotein Clc-like PF07062.7 XP_011272410.1 - 0.002 17.4 4.9 0.002 17.4 3.4 2.2 2 1 0 2 2 2 1 Clc-like MIG-14_Wnt-bd PF06664.7 XP_011272410.1 - 0.0061 15.4 0.9 0.0061 15.4 0.6 1.4 2 0 0 2 2 2 1 Wnt-binding factor required for Wnt secretion VIT1 PF01988.14 XP_011272410.1 - 0.12 11.8 5.6 0.039 13.4 1.0 2.1 2 0 0 2 2 2 0 VIT family Claudin_2 PF13903.1 XP_011272410.1 - 0.13 11.9 17.6 0.015 15.0 6.5 2.5 1 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction EphA2_TM PF14575.1 XP_011272410.1 - 0.25 11.7 0.0 0.25 11.7 0.0 3.0 3 1 1 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain CD20 PF04103.10 XP_011272410.1 - 0.51 10.2 9.4 0.49 10.3 2.4 2.9 2 1 0 2 2 2 0 CD20-like family Phage_holin_1 PF04531.8 XP_011272410.1 - 0.7 9.9 7.5 1.3 9.1 1.6 3.0 3 0 0 3 3 3 0 Bacteriophage holin Shisa PF13908.1 XP_011272410.1 - 1.1 9.3 0.0 1.1 9.3 0.0 2.7 2 1 1 3 3 2 0 Wnt and FGF inhibitory regulator OAD_gamma PF04277.8 XP_011272410.1 - 2.5 8.5 0.0 2.5 8.5 0.0 3.4 3 1 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain Tetraspannin PF00335.15 XP_011272410.1 - 3.3 6.9 17.7 2 7.6 7.4 2.6 2 1 0 2 2 2 0 Tetraspanin family DUF2207 PF09972.4 XP_011272410.1 - 5.5 5.4 9.4 13 4.2 5.6 1.9 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Mtr2 PF10429.4 XP_011272411.1 - 3.6e-49 166.6 0.0 4.3e-49 166.4 0.0 1.0 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 NTF2 PF02136.15 XP_011272411.1 - 0.035 14.4 0.0 0.048 14.0 0.0 1.3 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain SUR7 PF06687.7 XP_011272412.1 - 3.1e-14 53.0 4.2 3.4e-14 52.9 2.5 1.3 1 1 0 1 1 1 1 SUR7/PalI family DUF1510 PF07423.6 XP_011272412.1 - 0.015 14.7 0.1 0.19 11.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) AAR2 PF05282.6 XP_011272414.1 - 0.025 13.5 0.5 0.034 13.0 0.4 1.2 1 0 0 1 1 1 0 AAR2 protein Fig1 PF12351.3 XP_011272414.1 - 0.026 14.4 8.3 0.037 13.8 5.7 1.2 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 GATA PF00320.22 XP_011272415.1 - 1.4e-08 33.9 8.1 3.1e-08 32.8 5.6 1.7 1 0 0 1 1 1 1 GATA zinc finger zf-NADH-PPase PF09297.6 XP_011272415.1 - 7 6.2 8.5 1.2 8.7 0.3 3.0 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain Orn_Arg_deC_N PF02784.11 XP_011272416.1 - 4.5e-75 252.0 0.0 5.7e-75 251.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 XP_011272416.1 - 1.9e-30 104.9 0.1 3.3e-30 104.1 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.19 XP_011272416.1 - 0.0084 15.4 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel MFS_1 PF07690.11 XP_011272417.1 - 2.9e-36 124.9 34.5 2.9e-36 124.9 23.9 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF4131 PF13567.1 XP_011272417.1 - 0.033 13.6 0.2 0.033 13.6 0.1 3.3 4 1 0 4 4 4 0 Domain of unknown function (DUF4131) DUF4381 PF14316.1 XP_011272417.1 - 0.08 13.0 0.7 19 5.3 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) DUF4536 PF15055.1 XP_011272417.1 - 0.62 10.1 0.0 0.62 10.1 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4536) MFS_1 PF07690.11 XP_011272418.1 - 1e-07 31.0 0.3 1.3e-07 30.7 0.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 XP_011272418.1 - 0.0045 15.6 0.0 0.0046 15.5 0.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_Mycoplasma PF07672.8 XP_011272418.1 - 0.055 12.6 0.5 0.077 12.1 0.4 1.2 1 0 0 1 1 1 0 Mycoplasma MFS transporter MFS_1 PF07690.11 XP_011272419.1 - 3.3e-20 72.1 16.6 3.3e-20 72.1 11.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1469 PF07332.6 XP_011272419.1 - 3 7.5 4.6 2.8 7.6 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) SURF6 PF04935.7 XP_011272420.1 - 8.7e-48 162.4 51.5 8.7e-48 162.4 35.7 3.7 2 1 0 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.1 XP_011272420.1 - 3.2e-22 78.3 3.9 3.2e-22 78.3 2.7 8.2 6 2 0 6 6 6 1 60S ribosome biogenesis protein Rrp14 Lentiviral_Tat PF02998.9 XP_011272420.1 - 2.4 8.0 8.2 0.23 11.2 2.0 2.2 2 0 0 2 2 2 0 Lentiviral Tat protein SIS PF01380.17 XP_011272421.1 - 1.2e-10 41.0 0.1 2.4e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 SIS domain SIS_2 PF13580.1 XP_011272421.1 - 8.5e-07 28.7 0.5 0.00053 19.7 0.3 2.4 1 1 0 1 1 1 1 SIS domain Osmo_CC PF08946.5 XP_011272421.1 - 0.019 14.9 0.2 0.51 10.3 0.1 2.7 2 0 0 2 2 2 0 Osmosensory transporter coiled coil DUF946 PF06101.6 XP_011272422.1 - 1.9e-12 45.9 2.0 3.1e-12 45.2 1.4 1.3 1 0 0 1 1 1 1 Plant protein of unknown function (DUF946) Sfi1 PF08457.5 XP_011272424.1 - 9.4e-25 87.0 82.7 3.3e-21 75.3 39.3 2.6 1 1 2 3 3 3 3 Sfi1 spindle body protein Sfi1_C PF10638.4 XP_011272424.1 - 4.5e-12 46.3 2.7 2e-11 44.2 1.5 2.5 1 1 0 1 1 1 1 Spindle body associated protein C-terminus AMP-binding PF00501.23 XP_011272425.1 - 1.1e-68 231.5 0.0 1.4e-68 231.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Thioredox_DsbH PF03190.10 XP_011272426.1 - 0.027 14.2 0.0 0.031 13.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF255 DUF1681 PF07933.9 XP_011272426.1 - 0.074 12.6 0.1 0.076 12.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1681) DUF2222 PF09984.4 XP_011272426.1 - 0.12 11.7 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized signal transduction histidine kinase domain (DUF2222) EXOSC1 PF10447.4 XP_011272427.1 - 6.5e-33 112.5 0.2 1.9e-32 111.0 0.0 1.8 2 0 0 2 2 2 1 Exosome component EXOSC1/CSL4 S1 PF00575.18 XP_011272427.1 - 0.0012 18.8 1.6 0.24 11.4 0.0 2.8 3 0 0 3 3 3 2 S1 RNA binding domain Haemagg_act PF05860.8 XP_011272427.1 - 0.2 11.4 3.9 0.076 12.7 0.9 1.6 2 0 0 2 2 2 0 haemagglutination activity domain Prenylcys_lyase PF07156.9 XP_011272428.1 - 1.5e-37 129.3 0.3 2.1e-37 128.8 0.2 1.1 1 0 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.1 XP_011272428.1 - 5.8e-13 48.6 0.0 1.2e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 XP_011272428.1 - 4.7e-12 45.7 0.0 6.7e-08 32.0 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 XP_011272428.1 - 1e-05 25.6 0.0 0.031 14.3 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 XP_011272428.1 - 2e-05 23.7 0.0 0.00012 21.1 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 XP_011272428.1 - 0.00072 19.3 0.0 0.003 17.3 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 XP_011272428.1 - 0.0017 18.3 0.2 0.0087 15.9 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 XP_011272428.1 - 0.032 13.3 0.0 0.11 11.5 0.0 1.9 2 0 0 2 2 2 0 Thi4 family Ammonium_transp PF00909.16 XP_011272429.1 - 5e-123 410.5 29.7 5.7e-123 410.3 20.6 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family FMO-like PF00743.14 XP_011272430.1 - 2.4e-41 141.5 0.9 1.3e-22 79.6 0.2 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 XP_011272430.1 - 1.7e-17 64.1 0.0 1.2e-16 61.4 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 XP_011272430.1 - 6.2e-17 61.5 0.0 3.1e-12 46.0 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 XP_011272430.1 - 1.7e-12 47.6 0.0 1.1e-08 35.2 0.0 2.7 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 XP_011272430.1 - 7.1e-08 32.3 0.0 2.4e-05 24.1 0.0 2.9 2 1 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.9 XP_011272430.1 - 6.6e-06 24.8 0.0 1e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.1 XP_011272430.1 - 0.0011 18.9 0.0 0.0036 17.2 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DUF4318 PF14201.1 XP_011272430.1 - 0.0074 16.0 0.3 0.023 14.5 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4318) Pyr_redox PF00070.22 XP_011272430.1 - 0.0078 16.6 0.0 0.88 10.0 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 XP_011272430.1 - 0.011 14.8 0.1 0.17 10.9 0.0 2.1 2 0 0 2 2 2 0 Thi4 family F420_oxidored PF03807.12 XP_011272430.1 - 0.13 12.6 0.0 0.39 11.1 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent FAD_oxidored PF12831.2 XP_011272430.1 - 0.15 11.0 0.0 5 6.0 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Ammonium_transp PF00909.16 XP_011272431.1 - 1.8e-90 303.3 23.2 2.2e-90 303.0 16.1 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family WLM PF08325.5 XP_011272432.1 - 2.4e-46 157.9 0.0 3.6e-46 157.3 0.0 1.2 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.12 XP_011272432.1 - 0.0069 16.1 0.2 0.0069 16.1 0.1 1.8 2 1 0 2 2 2 1 Protein of unknown function DUF45 GATA PF00320.22 XP_011272433.1 - 9.7e-33 111.2 16.6 1.6e-16 59.3 2.4 2.5 2 0 0 2 2 2 2 GATA zinc finger RRN7 PF11781.3 XP_011272433.1 - 1.9e-06 27.2 2.6 0.0014 18.0 0.2 2.4 2 0 0 2 2 2 2 RNA polymerase I-specific transcription initiation factor Rrn7 TF_Zn_Ribbon PF08271.7 XP_011272433.1 - 4.3e-06 25.9 6.6 0.0084 15.4 1.2 2.6 2 0 0 2 2 2 2 TFIIB zinc-binding zf-ribbon_3 PF13248.1 XP_011272433.1 - 0.002 17.2 4.3 0.22 10.7 0.3 2.8 2 0 0 2 2 2 2 zinc-ribbon domain Auto_anti-p27 PF06677.7 XP_011272433.1 - 0.0041 16.8 3.1 0.73 9.6 0.2 2.4 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) ArfGap PF01412.13 XP_011272433.1 - 0.011 15.5 3.2 0.23 11.2 0.3 2.6 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf Zn-ribbon_8 PF09723.5 XP_011272433.1 - 0.019 14.9 1.0 0.49 10.4 0.1 2.6 2 0 0 2 2 2 0 Zinc ribbon domain DZR PF12773.2 XP_011272433.1 - 0.036 13.8 12.9 0.19 11.5 0.1 3.3 3 0 0 3 3 3 0 Double zinc ribbon NMD3 PF04981.8 XP_011272433.1 - 0.064 12.3 2.5 0.34 9.9 0.3 2.1 2 0 0 2 2 2 0 NMD3 family OrfB_Zn_ribbon PF07282.6 XP_011272433.1 - 0.26 10.9 14.8 0.099 12.3 1.5 3.1 3 0 0 3 3 3 0 Putative transposase DNA-binding domain eIF-5_eIF-2B PF01873.12 XP_011272433.1 - 0.3 10.7 4.3 7.5 6.2 0.2 2.5 2 0 0 2 2 2 0 Domain found in IF2B/IF5 HypA PF01155.14 XP_011272433.1 - 6.6 6.4 5.5 5.6 6.6 0.1 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family CLPTM1 PF05602.7 XP_011272434.1 - 9.1e-118 393.7 6.3 1.4e-117 393.1 4.4 1.3 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) DUF3974 PF13120.1 XP_011272434.1 - 0.056 13.2 1.7 0.15 11.9 0.0 2.5 3 1 0 3 3 3 0 Domain of unknown function (DUF3974) Acetyltransf_7 PF13508.1 XP_011272435.1 - 0.00011 22.2 0.0 0.00022 21.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 XP_011272435.1 - 0.00071 19.4 0.0 0.002 18.0 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Chitin_synth_1 PF01644.12 XP_011272436.1 - 7.1e-73 243.7 0.1 1.1e-72 243.1 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.10 XP_011272436.1 - 7.5e-29 100.5 6.6 2.9e-25 88.6 0.0 2.6 2 1 0 3 3 3 2 Chitin synthase Chitin_synth_1N PF08407.6 XP_011272436.1 - 1.6e-27 94.9 0.1 9.9e-27 92.4 0.1 2.3 2 0 0 2 2 2 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.1 XP_011272436.1 - 3.8e-13 49.6 4.6 3.8e-13 49.6 3.2 2.6 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 XP_011272436.1 - 5.4e-11 42.7 0.0 9e-10 38.7 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 XP_011272436.1 - 0.00012 21.7 0.0 0.0071 16.0 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Tyr_Deacylase PF02580.11 XP_011272437.1 - 2.1e-17 63.4 0.0 2.3e-17 63.3 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase RRM_1 PF00076.17 XP_011272439.1 - 1.2e-43 146.6 0.3 1.5e-20 72.5 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 XP_011272439.1 - 7.3e-31 105.9 0.0 8.1e-15 54.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 XP_011272439.1 - 5.1e-20 71.0 0.0 7.5e-09 35.3 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 XP_011272439.1 - 0.13 12.0 0.0 15 5.4 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Arrestin_N PF00339.24 XP_011272440.1 - 4.4e-19 68.7 0.2 1.9e-18 66.7 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain RNase_PH PF01138.16 XP_011272441.1 - 4.8e-18 65.7 0.2 1.8e-17 63.8 0.0 1.9 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 PEMT PF04191.8 XP_011272442.1 - 8.2e-59 196.2 12.5 1.3e-33 115.2 1.6 2.7 2 0 0 2 2 2 2 Phospholipid methyltransferase Reo_sigma1 PF01664.11 XP_011272442.1 - 0.022 13.8 0.3 0.053 12.6 0.1 1.7 2 0 0 2 2 2 0 Reovirus viral attachment protein sigma 1 Isochorismatase PF00857.15 XP_011272444.1 - 9.1e-19 68.0 0.0 1.2e-18 67.6 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family GST_N_2 PF13409.1 XP_011272445.1 - 1.2e-18 66.8 0.0 2.7e-18 65.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 XP_011272445.1 - 3.6e-11 42.7 0.0 6.1e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 XP_011272445.1 - 1.3e-05 25.0 0.0 2.3e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 XP_011272445.1 - 0.00018 21.9 0.0 0.0003 21.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 XP_011272445.1 - 0.00062 19.9 0.0 0.9 9.8 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain Thioredoxin_6 PF13848.1 XP_011272445.1 - 0.0061 16.3 2.1 0.0083 15.9 0.5 1.9 2 0 0 2 2 2 1 Thioredoxin-like domain tRNA_bind PF01588.15 XP_011272446.1 - 1.3e-24 85.8 0.1 1.8e-24 85.4 0.1 1.2 1 0 0 1 1 1 1 Putative tRNA binding domain Pyridox_oxase_2 PF12766.2 XP_011272447.1 - 6.4e-32 109.8 0.1 1.1e-31 109.0 0.1 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxidase PF01243.15 XP_011272447.1 - 3.3e-09 36.6 0.0 6.6e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase NmrA PF05368.8 XP_011272448.1 - 4.7e-15 55.4 0.1 6.1e-15 55.1 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 XP_011272448.1 - 2.7e-07 30.7 0.0 3.5e-06 27.1 0.0 2.0 2 0 0 2 2 2 1 NADH(P)-binding Saccharop_dh PF03435.13 XP_011272448.1 - 0.00029 19.9 0.0 0.00039 19.4 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 XP_011272448.1 - 0.012 15.8 0.1 0.075 13.3 0.0 2.2 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 XP_011272448.1 - 0.019 13.7 0.0 0.03 13.0 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Aminotran_3 PF00202.16 XP_011272449.1 - 1.5e-87 293.6 0.0 1.8e-87 293.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 XP_011272449.1 - 0.012 14.6 0.0 0.02 13.8 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II Chorismate_synt PF01264.16 XP_011272449.1 - 0.17 10.3 0.0 0.26 9.7 0.0 1.2 1 0 0 1 1 1 0 Chorismate synthase DUF2424 PF10340.4 XP_011272450.1 - 6.2e-13 48.1 1.1 3.7e-06 25.8 0.1 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF2424) Abhydrolase_3 PF07859.8 XP_011272450.1 - 3.4e-07 30.0 0.2 0.00027 20.5 0.1 3.0 1 1 1 2 2 2 2 alpha/beta hydrolase fold BRCT PF00533.21 XP_011272451.1 - 2e-11 43.8 0.0 4.5e-11 42.7 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 XP_011272451.1 - 1.6e-10 40.6 0.0 2.7e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain DUF3006 PF11213.3 XP_011272451.1 - 0.00031 20.4 0.1 0.0013 18.3 0.1 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) fn3 PF00041.16 XP_011272451.1 - 0.00043 20.3 0.1 0.0011 19.0 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III domain ATP-synt_F PF01990.12 XP_011272452.1 - 7.4e-28 96.7 0.1 9.2e-28 96.4 0.0 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit Transcrip_reg PF01709.15 XP_011272453.1 - 4.8e-76 254.9 2.9 5.5e-76 254.7 2.0 1.0 1 0 0 1 1 1 1 Transcriptional regulator DUF3693 PF12472.3 XP_011272453.1 - 0.13 11.8 0.3 0.25 10.9 0.2 1.4 1 0 0 1 1 1 0 Phage related protein Mito_carr PF00153.22 XP_011272454.1 - 7.1e-75 246.8 0.7 1.6e-24 85.3 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein UQ_con PF00179.21 XP_011272456.1 - 8.5e-37 125.7 0.1 1e-36 125.4 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Pox_C7_F8A PF03287.9 XP_011272456.1 - 0.063 12.9 0.2 0.11 12.1 0.1 1.4 1 1 0 1 1 1 0 Poxvirus C7/F8A protein E1-E2_ATPase PF00122.15 XP_011272458.1 - 3.9e-61 206.0 0.5 1e-60 204.6 0.3 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 XP_011272458.1 - 3.5e-42 143.9 5.0 3.5e-42 143.9 3.5 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 XP_011272458.1 - 1.6e-26 94.0 0.0 3.2e-25 89.8 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 XP_011272458.1 - 2.3e-15 56.3 0.0 6.3e-15 54.8 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 XP_011272458.1 - 4.8e-14 52.9 0.0 1.6e-13 51.2 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 XP_011272458.1 - 7.3e-12 44.5 0.6 2.8e-11 42.7 0.0 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 XP_011272458.1 - 0.00012 21.7 0.2 0.00012 21.7 0.1 2.9 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase tRNA_int_endo PF01974.12 XP_011272459.1 - 2.6e-15 55.9 0.0 5.3e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Nucleoplasmin PF03066.10 XP_011272459.1 - 0.019 14.4 0.6 0.037 13.5 0.4 1.4 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 XP_011272459.1 - 2.5 8.3 7.3 4.8 7.4 5.1 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Ecl1 PF12855.2 XP_011272460.1 - 6.3e-14 50.9 9.5 1.2e-13 50.1 6.6 1.5 1 0 0 1 1 1 1 Life-span regulatory factor zf-MYND PF01753.13 XP_011272460.1 - 0.026 14.3 4.2 0.056 13.3 2.9 1.5 1 0 0 1 1 1 0 MYND finger zf-C2H2_jaz PF12171.3 XP_011272460.1 - 4.8 7.4 8.9 0.42 10.8 2.5 2.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Rep_fac-A_C PF08646.5 XP_011272461.1 - 7.3e-58 194.4 0.7 2e-53 180.0 0.3 2.3 2 0 0 2 2 2 2 Replication factor-A C terminal domain tRNA_anti-codon PF01336.20 XP_011272461.1 - 2e-16 59.5 0.0 4.5e-11 42.4 0.0 4.1 3 1 1 4 4 4 2 OB-fold nucleic acid binding domain Rep-A_N PF04057.7 XP_011272461.1 - 4e-09 36.1 0.0 9.3e-09 34.9 0.0 1.6 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain Phi-29_GP4 PF05464.6 XP_011272462.1 - 0.08 12.8 0.2 0.088 12.7 0.2 1.1 1 0 0 1 1 1 0 Phi-29-like late genes activator (early protein GP4) Fe-S_biosyn PF01521.15 XP_011272462.1 - 0.081 12.8 0.3 0.1 12.5 0.2 1.2 1 0 0 1 1 1 0 Iron-sulphur cluster biosynthesis WD40 PF00400.27 XP_011272463.1 - 1.9e-09 37.0 4.8 7e-07 28.9 0.0 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat SET PF00856.23 XP_011272465.1 - 0.0055 17.0 10.7 0.26 11.5 0.2 4.5 2 1 1 3 3 3 2 SET domain CENP-T PF15511.1 XP_011272465.1 - 0.064 12.4 14.9 0.1 11.7 10.3 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T NAD_binding_10 PF13460.1 XP_011272466.1 - 8.6e-26 91.0 0.1 1e-25 90.8 0.0 1.0 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 XP_011272466.1 - 3.8e-07 30.4 0.1 6.7e-07 29.6 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.8 XP_011272466.1 - 1.2e-06 27.9 0.5 1.9e-06 27.3 0.4 1.4 1 1 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 XP_011272466.1 - 1.8e-05 23.6 0.4 2.5e-05 23.1 0.3 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 XP_011272466.1 - 8.1e-05 22.1 0.0 0.00017 21.0 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Ldh_1_N PF00056.18 XP_011272466.1 - 0.00021 21.1 0.2 0.00036 20.3 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain DapB_N PF01113.15 XP_011272466.1 - 0.0072 16.2 0.1 0.013 15.3 0.1 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Cadherin_pro PF08758.6 XP_011272466.1 - 0.028 14.1 0.0 0.06 13.1 0.0 1.5 1 0 0 1 1 1 0 Cadherin prodomain like Lectin_N PF03954.9 XP_011272466.1 - 0.065 12.6 0.1 0.12 11.8 0.1 1.4 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain NAD_binding_4 PF07993.7 XP_011272466.1 - 0.11 11.4 0.0 3.8 6.3 0.0 2.5 1 1 0 1 1 1 0 Male sterility protein NAD_binding_10 PF13460.1 XP_011272467.1 - 2.9e-27 95.8 0.1 3.4e-27 95.6 0.0 1.0 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 XP_011272467.1 - 5.8e-08 33.0 0.1 1e-07 32.2 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 XP_011272467.1 - 3.4e-05 22.7 0.2 4.9e-05 22.1 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 XP_011272467.1 - 4.6e-05 22.7 1.1 0.00012 21.3 0.8 1.6 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 XP_011272467.1 - 0.00024 20.6 0.0 0.00034 20.1 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.15 XP_011272467.1 - 0.0081 16.0 0.2 0.016 15.1 0.0 1.5 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Ldh_1_N PF00056.18 XP_011272467.1 - 0.016 15.0 0.1 0.03 14.1 0.1 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain DUF2145 PF09916.4 XP_011272467.1 - 0.06 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2145) NAD_binding_4 PF07993.7 XP_011272467.1 - 0.062 12.2 0.0 1.9 7.3 0.0 2.5 1 1 1 2 2 2 0 Male sterility protein ABC_membrane PF00664.18 XP_011272468.1 - 4e-60 203.5 36.6 7.1e-35 120.7 12.6 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 XP_011272468.1 - 2.1e-49 167.3 3.7 1.1e-28 100.2 0.1 3.2 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.14 XP_011272468.1 - 2.2e-14 53.2 1.8 1.7e-05 24.1 0.0 4.0 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 XP_011272468.1 - 6.8e-07 28.7 2.6 0.00042 19.7 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 XP_011272468.1 - 2e-06 27.1 1.4 0.008 15.3 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 XP_011272468.1 - 1.4e-05 25.5 1.3 0.22 12.0 0.1 3.4 3 0 0 3 3 3 2 Miro-like protein AAA_23 PF13476.1 XP_011272468.1 - 3.1e-05 24.3 7.0 0.049 13.9 3.4 3.5 2 1 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 XP_011272468.1 - 4.2e-05 23.1 0.4 0.24 10.8 0.0 2.6 3 0 0 3 3 3 2 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 XP_011272468.1 - 0.0014 18.5 1.6 0.74 9.7 0.1 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_25 PF13481.1 XP_011272468.1 - 0.0015 17.9 0.1 1.1 8.6 0.0 3.5 4 0 0 4 4 4 1 AAA domain AAA_16 PF13191.1 XP_011272468.1 - 0.0058 16.6 0.2 0.32 10.9 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.7 XP_011272468.1 - 0.0066 15.5 0.1 0.65 9.0 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_17 PF13207.1 XP_011272468.1 - 0.031 15.0 0.1 20 6.0 0.0 3.2 3 0 0 3 3 2 0 AAA domain AAA_22 PF13401.1 XP_011272468.1 - 0.035 14.2 4.4 6.3 6.9 0.7 3.7 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.1 XP_011272468.1 - 0.055 13.0 0.6 3.5 7.1 0.0 2.7 3 0 0 3 3 3 0 AAA domain cobW PF02492.14 XP_011272468.1 - 0.091 12.2 2.4 1.1 8.6 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.12 XP_011272468.1 - 0.22 11.0 3.6 7.4 6.0 0.2 3.2 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Arch_ATPase PF01637.13 XP_011272468.1 - 3.3 7.3 10.4 1.1 8.9 0.0 4.1 4 1 0 4 4 4 0 Archaeal ATPase NAD_binding_10 PF13460.1 XP_011272469.1 - 2e-25 89.8 0.0 2.4e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 XP_011272469.1 - 1.2e-06 28.0 0.2 2.1e-06 27.1 0.1 1.4 1 1 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 XP_011272469.1 - 2e-05 24.8 0.0 4.1e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 XP_011272469.1 - 2.7e-05 23.0 0.3 4.6e-05 22.2 0.2 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 XP_011272469.1 - 0.00022 21.1 0.1 0.00065 19.6 0.0 1.8 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.17 XP_011272469.1 - 0.0021 18.5 0.0 0.0034 17.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_4 PF07993.7 XP_011272469.1 - 0.0023 16.8 0.0 0.82 8.5 0.0 3.0 1 1 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 XP_011272469.1 - 0.0031 16.9 0.3 0.0061 16.0 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 XP_011272469.1 - 0.023 13.6 0.0 0.033 13.1 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase DUF4162 PF13732.1 XP_011272469.1 - 0.033 14.6 0.3 0.2 12.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) DXP_reductoisom PF02670.11 XP_011272469.1 - 0.088 13.3 0.1 0.2 12.1 0.1 1.8 1 1 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Shikimate_DH PF01488.15 XP_011272469.1 - 0.11 12.6 0.3 0.2 11.7 0.2 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase KH_5 PF13184.1 XP_011272469.1 - 0.39 10.5 3.3 4.8 7.0 0.2 2.7 2 1 0 2 2 2 0 NusA-like KH domain Surf_Ag_VNR PF07244.10 XP_011272469.1 - 2.4 8.6 6.2 1.6 9.1 0.3 3.0 2 1 2 4 4 4 0 Surface antigen variable number repeat NAD_binding_10 PF13460.1 XP_011272470.1 - 1.1e-27 97.2 0.0 1.3e-27 97.0 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 XP_011272470.1 - 7.4e-15 54.8 0.2 1.1e-14 54.3 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 XP_011272470.1 - 5.4e-13 48.9 0.0 5.7e-12 45.5 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 XP_011272470.1 - 1.2e-05 24.4 0.1 0.015 14.2 0.1 2.9 1 1 0 2 2 2 1 Male sterility protein F420_oxidored PF03807.12 XP_011272470.1 - 2.7e-05 24.5 0.1 6.5e-05 23.2 0.0 1.7 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.19 XP_011272470.1 - 6.6e-05 23.2 0.1 0.00012 22.3 0.1 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 XP_011272470.1 - 7.6e-05 22.6 0.0 0.00014 21.7 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus TrkA_N PF02254.13 XP_011272470.1 - 8.7e-05 22.5 0.8 0.00018 21.4 0.1 1.8 2 0 0 2 2 2 1 TrkA-N domain Shikimate_DH PF01488.15 XP_011272470.1 - 0.00082 19.4 0.1 0.0016 18.5 0.1 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3Beta_HSD PF01073.14 XP_011272470.1 - 0.0012 17.6 0.0 0.0018 17.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family ApbA PF02558.11 XP_011272470.1 - 0.0014 18.0 0.1 0.013 14.9 0.0 2.1 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Rossmann-like PF10727.4 XP_011272470.1 - 0.02 14.6 0.0 0.039 13.6 0.0 1.6 1 0 0 1 1 1 0 Rossmann-like domain NAD_binding_2 PF03446.10 XP_011272470.1 - 0.021 14.6 0.2 0.068 13.0 0.0 1.9 2 1 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase DFP PF04127.10 XP_011272470.1 - 0.034 13.7 0.0 0.061 12.9 0.0 1.5 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein adh_short PF00106.20 XP_011272470.1 - 0.035 14.0 0.0 1.2 8.9 0.0 2.1 2 0 0 2 2 2 0 short chain dehydrogenase AlaDh_PNT_C PF01262.16 XP_011272470.1 - 0.052 13.1 0.1 0.089 12.3 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Polysacc_synt_2 PF02719.10 XP_011272470.1 - 0.073 11.9 0.5 0.19 10.6 0.3 1.7 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_Gly3P_dh_N PF01210.18 XP_011272470.1 - 0.17 11.6 1.2 0.8 9.4 0.1 2.2 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 XP_011272470.1 - 0.8 9.3 2.9 0.47 10.0 0.7 1.8 2 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Inositol_P PF00459.20 XP_011272471.1 - 1.1e-52 179.0 0.2 2.4e-52 177.9 0.1 1.5 1 1 0 1 1 1 1 Inositol monophosphatase family EF-hand_4 PF12763.2 XP_011272471.1 - 0.09 12.5 0.0 0.25 11.0 0.0 1.8 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand SCA7 PF08313.7 XP_011272472.1 - 1.6e-31 107.6 1.5 1.6e-31 107.6 1.0 2.8 2 0 0 2 2 2 1 SCA7, zinc-binding domain Sgf11 PF08209.6 XP_011272472.1 - 0.081 12.2 0.2 0.14 11.5 0.1 1.4 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) DUF2201_N PF13203.1 XP_011272472.1 - 0.43 9.6 34.4 0.35 9.9 14.0 2.3 2 0 0 2 2 2 0 Putative metallopeptidase domain SAPS PF04499.10 XP_011272472.1 - 5.8 5.4 35.0 0.24 9.9 3.7 2.2 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Glycos_transf_1 PF00534.15 XP_011272473.1 - 6.6e-32 110.2 0.4 7.2e-31 106.9 0.2 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 XP_011272473.1 - 1.8e-06 27.7 0.0 7.2e-06 25.8 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 XP_011272473.1 - 1.6e-05 25.0 0.0 0.00013 22.1 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 XP_011272473.1 - 0.00016 21.8 0.0 0.00023 21.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_20 PF00982.16 XP_011272473.1 - 0.0066 14.9 0.1 0.011 14.2 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 FlgH PF02107.11 XP_011272474.1 - 0.07 12.7 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Flagellar L-ring protein Radical_SAM PF04055.16 XP_011272477.1 - 4.2e-24 85.5 0.0 8.2e-24 84.6 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.7 XP_011272477.1 - 5.2e-20 71.3 0.0 1.5e-19 69.8 0.0 1.9 1 0 0 1 1 1 1 Wyosine base formation Flavodoxin_1 PF00258.20 XP_011272477.1 - 7.9e-12 45.3 0.0 6.8e-11 42.3 0.0 2.4 2 0 0 2 2 2 1 Flavodoxin DUF1992 PF09350.5 XP_011272478.1 - 2.8e-15 55.8 0.2 7.8e-15 54.4 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1992) SET PF00856.23 XP_011272479.1 - 2.1e-05 24.9 0.0 5.2e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 SET domain Pkinase PF00069.20 XP_011272480.1 - 3.6e-71 239.3 0.3 4.7e-71 238.9 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011272480.1 - 1.1e-46 158.9 0.0 1.5e-46 158.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 XP_011272480.1 - 7.7e-09 34.9 0.0 1.5e-07 30.7 0.0 2.1 2 0 0 2 2 2 1 Kinase-like YrbL-PhoP_reg PF10707.4 XP_011272480.1 - 0.0016 17.8 0.2 0.0029 16.9 0.1 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.18 XP_011272480.1 - 0.018 14.7 0.1 0.22 11.2 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 XP_011272480.1 - 0.036 13.1 0.0 0.064 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 XP_011272480.1 - 0.073 12.4 3.9 0.26 10.6 2.2 2.2 2 1 0 2 2 2 0 RIO1 family DEAD PF00270.24 XP_011272481.1 - 5.2e-30 104.1 1.4 2.8e-29 101.7 0.0 2.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 XP_011272481.1 - 4e-15 55.4 0.0 1.2e-14 53.9 0.0 1.9 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 XP_011272481.1 - 1.7e-08 34.5 0.8 6.3e-08 32.6 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 XP_011272481.1 - 1.3e-06 27.4 0.4 2.9e-06 26.2 0.3 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.1 XP_011272481.1 - 1.1e-05 25.5 0.1 0.00022 21.3 0.0 2.9 1 1 1 2 2 2 1 AAA domain SRP72 PF08492.7 XP_011272482.1 - 3.6e-13 49.6 3.7 3.6e-13 49.6 2.6 2.5 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_12 PF13424.1 XP_011272482.1 - 2.7e-09 36.8 0.9 0.013 15.4 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 XP_011272482.1 - 3.9e-05 23.2 0.3 0.028 14.3 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 XP_011272482.1 - 4e-05 23.7 3.4 0.23 12.0 0.0 5.3 7 0 0 7 7 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 XP_011272482.1 - 4.2e-05 23.0 0.8 0.013 15.2 0.1 4.3 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 XP_011272482.1 - 7.9e-05 22.2 0.1 0.057 13.0 0.0 3.1 2 0 0 2 2 2 1 TPR repeat Apc3 PF12895.2 XP_011272482.1 - 0.00011 22.3 11.4 0.016 15.3 0.2 5.2 4 2 1 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 XP_011272482.1 - 0.00027 20.4 10.6 0.43 10.4 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 XP_011272482.1 - 0.00036 20.9 0.0 0.51 11.1 0.0 4.6 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 XP_011272482.1 - 0.0023 18.2 9.2 3 8.2 0.0 5.2 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 XP_011272482.1 - 0.008 16.2 0.6 3.3 8.1 0.1 3.6 2 0 0 2 2 2 1 Tetratricopeptide repeat RPN7 PF10602.4 XP_011272482.1 - 0.0081 15.5 0.1 0.49 9.7 0.0 2.5 2 0 0 2 2 2 1 26S proteasome subunit RPN7 TPR_1 PF00515.23 XP_011272482.1 - 0.013 15.1 2.0 0.47 10.1 0.1 4.0 3 1 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 XP_011272482.1 - 0.017 14.9 0.1 1.7 8.5 0.0 3.1 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat DUF2225 PF09986.4 XP_011272482.1 - 0.018 14.5 6.0 0.12 11.7 0.1 3.3 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_16 PF13432.1 XP_011272482.1 - 0.06 14.0 0.0 0.47 11.2 0.0 2.5 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_4 PF07721.9 XP_011272482.1 - 0.18 12.2 0.0 1.2 9.7 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Nefa_Nip30_N PF10187.4 XP_011272482.1 - 1.3 9.2 8.3 0.056 13.6 0.9 2.4 2 0 0 2 2 2 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 UPF0113 PF03657.8 XP_011272483.1 - 7e-10 38.7 0.1 1e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) DAP3 PF10236.4 XP_011272484.1 - 9.6e-68 228.3 0.4 1.4e-67 227.8 0.3 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 ABC_tran PF00005.22 XP_011272484.1 - 7e-05 23.1 0.1 0.00017 21.9 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.1 XP_011272484.1 - 0.00078 19.4 0.0 0.0026 17.7 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 XP_011272484.1 - 0.0027 17.2 0.1 0.0061 16.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 XP_011272484.1 - 0.0083 15.5 0.0 1.2 8.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain MutS_V PF00488.16 XP_011272484.1 - 0.0099 15.3 0.0 0.024 14.0 0.0 1.6 1 0 0 1 1 1 1 MutS domain V ArgK PF03308.11 XP_011272484.1 - 0.017 13.8 0.0 0.031 13.0 0.0 1.3 1 0 0 1 1 1 0 ArgK protein NACHT PF05729.7 XP_011272484.1 - 0.041 13.5 0.1 0.14 11.8 0.0 1.9 2 0 0 2 2 2 0 NACHT domain DUF258 PF03193.11 XP_011272484.1 - 0.055 12.6 0.1 0.13 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 mRNA_cap_enzyme PF01331.14 XP_011272485.1 - 2.9e-51 173.8 0.0 4.9e-51 173.1 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 XP_011272485.1 - 1.7e-23 82.9 1.9 4.4e-23 81.6 1.3 1.7 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 XP_011272485.1 - 3.4e-06 26.5 0.0 0.00019 20.8 0.0 2.6 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DUF573 PF04504.9 XP_011272486.1 - 0.044 14.0 1.7 39 4.5 0.6 3.4 3 0 0 3 3 3 0 Protein of unknown function, DUF573 CoiA PF06054.6 XP_011272487.1 - 0.0016 17.3 0.1 0.0021 17.0 0.0 1.1 1 0 0 1 1 1 1 Competence protein CoiA-like family Spc7 PF08317.6 XP_011272487.1 - 0.056 12.0 9.2 0.0085 14.7 2.0 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Pkinase PF00069.20 XP_011272488.1 - 1.1e-60 205.0 0.0 1.6e-60 204.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011272488.1 - 2.4e-26 92.3 0.0 1.7e-20 73.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 XP_011272488.1 - 8.3e-05 21.6 0.0 0.00016 20.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Trypan_PARP PF05887.6 XP_011272488.1 - 1 9.1 5.6 2.1 8.1 3.9 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PHD PF00628.24 XP_011272489.1 - 1.2e-12 47.2 42.1 3.1e-08 33.1 3.5 5.0 4 0 0 4 4 4 2 PHD-finger BAH PF01426.13 XP_011272489.1 - 9.2e-12 44.7 0.4 3.3e-11 42.9 0.3 2.0 1 0 0 1 1 1 1 BAH domain zf-HC5HC2H_2 PF13832.1 XP_011272489.1 - 4.9e-07 29.7 27.2 1.2e-05 25.3 1.3 4.3 4 0 0 4 4 4 3 PHD-zinc-finger like domain PHD_2 PF13831.1 XP_011272489.1 - 6.9e-06 25.2 1.7 6.9e-06 25.2 1.2 4.6 4 0 0 4 4 4 1 PHD-finger LRR_9 PF14580.1 XP_011272490.1 - 1.9e-37 128.4 2.7 3.4e-37 127.7 1.9 1.4 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 XP_011272490.1 - 3.5e-06 26.5 28.5 0.0046 16.5 0.3 4.2 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 XP_011272490.1 - 0.00014 21.5 12.0 0.00046 19.8 0.7 2.9 1 1 1 2 2 2 2 Leucine rich repeat LRR_7 PF13504.1 XP_011272490.1 - 0.26 11.6 7.3 7.9 7.1 0.3 4.6 4 1 1 5 5 5 0 Leucine rich repeat HK PF02110.10 XP_011272491.1 - 1.2e-75 253.9 2.9 6.3e-75 251.5 2.0 2.0 1 1 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 XP_011272491.1 - 2.3e-55 186.4 0.1 3.5e-55 185.9 0.1 1.3 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI Phos_pyr_kin PF08543.7 XP_011272491.1 - 0.00036 19.8 0.0 0.0007 18.8 0.0 1.4 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Ubiq_cyt_C_chap PF03981.7 XP_011272492.1 - 8.4e-41 139.1 1.1 1.3e-40 138.5 0.8 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone CDI PF02234.14 XP_011272492.1 - 0.048 13.4 0.2 0.12 12.2 0.1 1.7 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor WAC_Acf1_DNA_bd PF10537.4 XP_011272493.1 - 3.2e-39 133.2 0.7 1.5e-38 131.0 0.5 2.3 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 XP_011272493.1 - 2.3e-13 49.7 0.2 4.1e-13 48.8 0.2 1.4 1 0 0 1 1 1 1 DDT domain WHIM2 PF15613.1 XP_011272493.1 - 3.1e-06 26.8 1.1 1e-05 25.2 0.8 2.0 1 1 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM3 PF15614.1 XP_011272493.1 - 0.00056 19.6 0.6 0.0025 17.5 0.4 2.2 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 3 Med31 PF05669.7 XP_011272493.1 - 0.0053 16.4 0.5 0.021 14.5 0.3 2.0 1 0 0 1 1 1 1 SOH1 WHIM1 PF15612.1 XP_011272493.1 - 0.0081 16.0 0.0 0.025 14.5 0.0 1.8 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 DUF663 PF04950.7 XP_011272494.1 - 1.2e-95 319.8 0.0 1.2e-95 319.8 0.0 3.1 3 1 1 4 4 4 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 XP_011272494.1 - 8.8e-30 102.0 0.0 3.1e-29 100.3 0.0 2.1 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 XP_011272494.1 - 4e-08 32.9 1.4 1.1e-05 24.9 0.0 2.9 2 1 1 3 3 2 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 XP_011272494.1 - 1.1e-06 28.5 0.0 3.2e-06 27.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 XP_011272494.1 - 2.9e-06 27.3 0.0 8e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 XP_011272494.1 - 5.9e-06 26.5 0.0 1.6e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 XP_011272494.1 - 1.2e-05 25.4 0.0 3.9e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 XP_011272494.1 - 2.6e-05 23.9 0.2 7.9e-05 22.3 0.1 1.9 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 XP_011272494.1 - 2.9e-05 23.7 0.1 7.5e-05 22.4 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 XP_011272494.1 - 3.5e-05 24.6 0.0 3.5e-05 24.6 0.0 4.2 3 1 0 3 3 1 1 AAA domain Miro PF08477.8 XP_011272494.1 - 0.0009 19.7 0.0 0.0036 17.7 0.0 2.1 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 XP_011272494.1 - 0.0012 18.8 0.1 0.0058 16.5 0.1 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.7 XP_011272494.1 - 0.0013 18.3 0.0 0.0029 17.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.1 XP_011272494.1 - 0.0019 18.4 0.0 0.0019 18.4 0.0 4.7 3 1 0 4 4 3 1 AAA domain AAA_28 PF13521.1 XP_011272494.1 - 0.0019 18.1 0.0 0.0075 16.2 0.0 2.1 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 XP_011272494.1 - 0.0044 17.1 0.0 0.013 15.6 0.0 1.8 1 0 0 1 1 1 1 RNA helicase ABC_tran PF00005.22 XP_011272494.1 - 0.0045 17.2 0.5 0.021 15.1 0.0 2.4 2 0 0 2 2 1 1 ABC transporter NTPase_1 PF03266.10 XP_011272494.1 - 0.0047 16.6 0.1 0.0099 15.6 0.1 1.5 1 0 0 1 1 1 1 NTPase PduV-EutP PF10662.4 XP_011272494.1 - 0.011 15.2 0.5 0.04 13.3 0.0 2.1 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 XP_011272494.1 - 0.013 14.9 0.0 0.03 13.7 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.9 XP_011272494.1 - 0.014 15.1 0.1 0.036 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.1 XP_011272494.1 - 0.026 14.1 0.0 0.026 14.1 0.0 3.4 3 1 0 3 3 3 0 AAA domain AAA_25 PF13481.1 XP_011272494.1 - 0.048 13.0 0.0 0.13 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain Arf PF00025.16 XP_011272496.1 - 1.5e-63 213.1 0.0 2.4e-63 212.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 XP_011272496.1 - 1.5e-10 40.3 0.1 5e-07 28.7 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 XP_011272496.1 - 1.6e-10 40.4 0.0 2.5e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 XP_011272496.1 - 2.5e-08 33.4 0.0 4.4e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Ras family Miro PF08477.8 XP_011272496.1 - 7.3e-07 29.7 0.0 1.7e-06 28.5 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 XP_011272496.1 - 4.8e-06 26.5 0.0 9.2e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 XP_011272496.1 - 0.00047 19.3 0.0 0.00068 18.8 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Amidase02_C PF12123.3 XP_011272496.1 - 0.12 11.9 0.0 0.31 10.7 0.0 1.6 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase PduV-EutP PF10662.4 XP_011272496.1 - 0.14 11.6 0.0 0.39 10.1 0.0 1.7 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation p450 PF00067.17 XP_011272497.1 - 4.5e-54 183.7 0.1 5.6e-54 183.4 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 XP_011272498.1 - 1e-46 159.3 34.0 5.1e-42 143.8 15.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 XP_011272498.1 - 7.9e-15 54.3 25.4 2.4e-13 49.5 17.9 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 XP_011272498.1 - 3.3e-07 29.0 10.2 0.00012 20.6 0.0 2.4 1 1 1 2 2 2 2 MFS/sugar transport protein ATG22 PF11700.3 XP_011272499.1 - 1.1e-112 377.0 15.2 1.2e-112 376.8 10.5 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like IL6 PF00489.12 XP_011272499.1 - 0.0051 16.4 0.0 0.0084 15.6 0.0 1.2 1 0 0 1 1 1 1 Interleukin-6/G-CSF/MGF family Coatomer_WDAD PF04053.9 XP_011272500.1 - 4.5e-167 556.3 7.8 5.5e-166 552.7 2.0 2.1 2 0 0 2 2 2 2 Coatomer WD associated region WD40 PF00400.27 XP_011272500.1 - 8e-45 149.1 4.8 1.2e-10 40.8 0.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat TPR_8 PF13181.1 XP_011272500.1 - 9e-07 28.2 4.0 0.15 11.9 0.2 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 XP_011272500.1 - 4e-06 26.3 1.4 0.6 10.1 0.0 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 XP_011272500.1 - 1.2e-05 24.6 0.6 1.3 8.7 0.0 4.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 XP_011272500.1 - 1.9e-05 24.2 3.0 0.071 12.7 0.0 4.0 3 1 0 3 3 3 2 TPR repeat BBS2_Mid PF14783.1 XP_011272500.1 - 2.1e-05 24.2 0.0 0.04 13.7 0.0 4.0 4 1 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.3 XP_011272500.1 - 3e-05 22.3 4.3 0.06 11.4 0.2 4.0 2 2 1 3 3 3 2 Nucleoporin Nup120/160 TPR_12 PF13424.1 XP_011272500.1 - 0.0033 17.3 1.2 18 5.3 0.0 3.7 2 1 2 4 4 4 0 Tetratricopeptide repeat Clathrin PF00637.15 XP_011272500.1 - 0.01 15.4 7.0 0.24 10.9 0.4 2.4 1 1 1 2 2 2 0 Region in Clathrin and VPS TPR_7 PF13176.1 XP_011272500.1 - 0.17 11.7 1.0 57 3.8 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat FtsJ PF01728.14 XP_011272501.1 - 1e-31 110.3 0.0 1.4e-31 109.8 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.1 XP_011272501.1 - 0.0047 16.6 0.0 0.0079 15.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 XP_011272501.1 - 0.021 15.4 0.0 0.047 14.2 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.1 XP_011272501.1 - 0.065 12.8 0.0 0.23 11.0 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Ribosomal_L1 PF00687.16 XP_011272502.1 - 1.6e-45 155.1 3.0 1.8e-45 154.9 2.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Cyclin PF08613.6 XP_011272503.1 - 5e-25 88.6 0.3 9.7e-24 84.4 0.1 2.1 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 XP_011272503.1 - 0.00021 20.8 0.1 0.00035 20.1 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain ACC_central PF08326.7 XP_011272504.1 - 2.5e-265 882.0 0.0 3.1e-265 881.7 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 XP_011272504.1 - 5.2e-172 572.6 0.0 7e-172 572.1 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 XP_011272504.1 - 2.9e-52 177.0 0.0 5.7e-52 176.0 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 XP_011272504.1 - 2.2e-26 92.1 0.0 5.8e-26 90.7 0.0 1.8 2 0 0 2 2 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 XP_011272504.1 - 2.7e-20 72.3 0.0 3.5e-19 68.7 0.0 3.0 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 XP_011272504.1 - 3.2e-18 65.1 0.2 9e-18 63.6 0.1 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 XP_011272504.1 - 8.7e-11 41.8 0.0 2.2e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 XP_011272504.1 - 7.3e-10 38.0 0.0 0.00011 21.1 0.0 3.0 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 XP_011272504.1 - 0.00029 20.3 0.0 0.00074 18.9 0.0 1.7 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 XP_011272504.1 - 0.00042 20.2 0.0 0.0018 18.1 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp PF02222.17 XP_011272504.1 - 0.0012 18.1 0.1 0.018 14.4 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 XP_011272504.1 - 0.0017 17.9 0.1 0.85 9.3 0.0 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like Peptidase_A22B PF04258.8 XP_011272506.1 - 9.7e-54 182.8 5.6 9.7e-54 182.8 3.9 1.7 1 1 0 1 1 1 1 Signal peptide peptidase Shisa PF13908.1 XP_011272506.1 - 0.035 14.2 0.1 0.82 9.8 0.0 2.5 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator DUF1119 PF06550.6 XP_011272506.1 - 0.3 10.1 13.5 0.013 14.6 5.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1119) Ribosomal_L4 PF00573.17 XP_011272509.1 - 1.1e-46 158.6 0.8 1.8e-46 157.9 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 XP_011272509.1 - 1.8e-30 104.6 1.6 1.8e-30 104.6 1.1 2.5 2 1 1 3 3 3 1 60S ribosomal protein L4 C-terminal domain PP2C PF00481.16 XP_011272510.1 - 1.4e-74 250.7 0.2 9.4e-55 185.7 0.1 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C Med2 PF11214.3 XP_011272511.1 - 0.0001 22.3 14.1 0.0001 22.3 9.8 2.6 2 1 1 3 3 3 1 Mediator complex subunit 2 DUF3484 PF11983.3 XP_011272511.1 - 0.0086 16.8 5.5 0.0086 16.8 3.8 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3484) DUF2346 PF09803.4 XP_011272511.1 - 0.015 15.1 0.3 0.059 13.2 0.2 2.1 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2346) FCP1_C PF09309.5 XP_011272511.1 - 0.68 9.1 8.5 1.3 8.2 5.9 1.6 1 1 0 1 1 1 0 FCP1, C-terminal Suf PF05843.9 XP_011272511.1 - 0.84 9.3 7.9 1.1 8.9 5.5 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Presenilin PF01080.12 XP_011272511.1 - 2 7.1 3.9 2.4 6.8 2.7 1.1 1 0 0 1 1 1 0 Presenilin Vma12 PF11712.3 XP_011272511.1 - 2.8 7.6 5.2 4.9 6.8 3.6 1.4 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase ATP-synt_DE_N PF02823.11 XP_011272512.1 - 1e-22 79.6 0.1 1.5e-22 79.1 0.0 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain DUF464 PF04327.7 XP_011272513.1 - 0.015 15.5 1.6 0.038 14.2 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF464) DUF3221 PF11518.3 XP_011272513.1 - 1.8 8.2 6.2 0.93 9.1 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3221) Cu_amine_oxid PF01179.15 XP_011272514.1 - 1.1e-167 557.9 0.0 1.4e-167 557.6 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 XP_011272514.1 - 3.5e-25 88.0 0.1 7.2e-25 86.9 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 XP_011272514.1 - 9.2e-19 67.3 0.0 1.9e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Rad21_Rec8_N PF04825.8 XP_011272522.1 - 7.4e-37 125.7 0.2 1.8e-36 124.4 0.1 1.6 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 XP_011272522.1 - 4.8e-10 38.4 0.0 1.1e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 XP_011272522.1 - 0.004 16.7 6.4 0.027 14.0 4.5 2.6 1 1 0 1 1 1 1 ScpA/B protein Pectate_lyase PF03211.8 XP_011272524.1 - 0.045 13.1 0.0 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 Pectate lyase TauD PF02668.11 XP_011272524.1 - 0.08 12.6 0.1 0.16 11.6 0.1 1.4 1 0 0 1 1 1 0 Taurine catabolism dioxygenase TauD, TfdA family LCM PF04072.9 XP_011272525.1 - 9.8e-18 64.3 0.0 1.6e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.1 XP_011272525.1 - 3.1e-07 30.0 0.0 0.41 10.4 0.0 5.1 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_3 PF13415.1 XP_011272525.1 - 4.8e-07 29.7 0.2 0.004 17.2 0.0 4.7 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_5 PF13854.1 XP_011272525.1 - 1.1e-06 28.4 0.0 2.3 8.2 0.0 4.9 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.1 XP_011272525.1 - 0.002 18.1 5.1 4.2 7.7 0.0 5.4 5 1 1 6 6 6 1 Kelch motif Syja_N PF02383.13 XP_011272526.1 - 1.3e-95 319.8 2.1 2.2e-95 319.0 0.3 2.1 2 0 0 2 2 2 1 SacI homology domain DUF3450 PF11932.3 XP_011272528.1 - 0.044 13.0 7.8 0.025 13.8 3.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) DUF342 PF03961.8 XP_011272528.1 - 0.28 9.5 6.6 0.35 9.2 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) CybS PF05328.7 XP_011272529.1 - 5.5e-50 168.4 0.6 8.8e-50 167.7 0.2 1.4 2 0 0 2 2 2 1 CybS Sdh_cyt PF01127.17 XP_011272529.1 - 0.0078 16.0 2.4 0.62 9.8 1.7 2.2 1 1 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF1413 PF07205.6 XP_011272530.1 - 0.068 12.7 0.3 0.27 10.8 0.2 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1413) PCI PF01399.22 XP_011272530.1 - 0.18 12.1 2.6 0.38 11.0 1.8 1.6 1 0 0 1 1 1 0 PCI domain PXA PF02194.10 XP_011272531.1 - 5.2e-26 91.3 0.2 5.2e-26 91.3 0.2 2.1 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.7 XP_011272531.1 - 0.00013 22.0 0.2 0.072 13.1 0.0 2.9 3 0 0 3 3 3 2 Sorting nexin C terminal CCDC32 PF14989.1 XP_011272531.1 - 0.47 10.2 6.3 0.14 11.9 0.8 2.6 3 0 0 3 3 3 0 Coiled-coil domain containing 32 PseudoU_synth_2 PF00849.17 XP_011272532.1 - 5.3e-18 65.3 0.0 7.5e-18 64.8 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase Nipped-B_C PF12830.2 XP_011272533.1 - 2.2e-39 135.0 2.4 2.2e-39 135.0 1.7 4.8 5 0 0 5 5 5 2 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 XP_011272533.1 - 2.7e-09 36.7 0.2 4.5e-08 32.8 0.3 3.1 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion HEAT_2 PF13646.1 XP_011272533.1 - 0.017 15.4 0.1 0.14 12.4 0.0 2.5 2 1 1 3 3 3 0 HEAT repeats PEP-utilisers_N PF05524.8 XP_011272533.1 - 0.26 11.0 0.0 0.72 9.6 0.0 1.7 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal DUF1451 PF07295.6 XP_011272533.1 - 0.37 10.5 3.6 0.22 11.3 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1451) GspL_C PF12693.2 XP_011272534.1 - 0.02 14.6 0.1 0.032 14.0 0.1 1.2 1 0 0 1 1 1 0 GspL periplasmic domain TMEM107 PF14995.1 XP_011272534.1 - 0.022 14.8 0.7 4 7.5 0.1 2.1 2 0 0 2 2 2 0 Transmembrane protein UPF0233 PF06781.7 XP_011272534.1 - 0.065 12.8 0.3 1.1 8.9 0.1 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0233) EMP24_GP25L PF01105.19 XP_011272534.1 - 0.88 9.2 6.1 0.83 9.3 1.3 2.0 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD Glyco_tran_WbsX PF14307.1 XP_011272536.1 - 0.003 16.7 2.6 0.0045 16.1 1.8 1.2 1 0 0 1 1 1 1 Glycosyltransferase WbsX DUF3201 PF11447.3 XP_011272536.1 - 0.024 14.0 0.1 0.058 12.7 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3201) SAS4 PF15460.1 XP_011272537.1 - 7.4e-29 99.5 7.6 7.4e-29 99.5 5.3 1.9 2 0 0 2 2 2 1 Something about silencing, SAS, complex subunit 4 Pkinase PF00069.20 XP_011272538.1 - 8.1e-60 202.1 0.0 2.6e-38 131.6 0.2 2.6 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011272538.1 - 4.5e-26 91.4 0.0 1.1e-20 73.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 XP_011272538.1 - 1.8e-06 27.9 0.1 4e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.1 XP_011272538.1 - 2.7e-06 26.5 0.0 0.0002 20.4 0.0 2.3 2 0 0 2 2 2 1 Kinase-like PAS_9 PF13426.1 XP_011272538.1 - 0.0072 16.6 0.0 0.019 15.3 0.0 1.8 1 0 0 1 1 1 1 PAS domain APH PF01636.18 XP_011272538.1 - 0.0074 16.0 0.0 0.17 11.5 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 XP_011272538.1 - 0.022 14.1 0.1 0.11 11.8 0.1 2.1 2 0 0 2 2 2 0 RIO1 family Kdo PF06293.9 XP_011272538.1 - 0.12 11.3 0.1 0.45 9.5 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Bac_luciferase PF00296.15 XP_011272539.1 - 4.8e-46 157.3 0.0 6.6e-46 156.8 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase tRNA-synt_2d PF01409.15 XP_011272540.1 - 1.6e-87 292.7 0.0 2.1e-87 292.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 XP_011272540.1 - 6.7e-06 25.0 0.0 0.00011 21.0 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 XP_011272540.1 - 0.00034 20.2 0.0 0.0006 19.4 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) DUF1128 PF06569.6 XP_011272541.1 - 0.0094 15.6 0.0 0.031 13.9 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1128) zf-C2H2 PF00096.21 XP_011272541.1 - 0.026 14.8 0.2 0.082 13.2 0.1 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type Fcf2 PF08698.6 XP_011272542.1 - 6.6e-35 119.0 2.5 6.6e-35 119.0 1.7 2.2 3 1 0 3 3 3 1 Fcf2 pre-rRNA processing Pkip-1 PF06878.6 XP_011272542.1 - 0.13 12.1 6.7 0.34 10.7 0.5 2.2 2 0 0 2 2 2 0 Pkip-1 protein HEAT_EZ PF13513.1 XP_011272543.1 - 2.4e-14 53.3 9.9 5.1e-05 23.6 0.0 8.5 9 1 1 10 10 9 4 HEAT-like repeat HEAT PF02985.17 XP_011272543.1 - 2.4e-12 45.8 19.2 0.017 15.1 0.0 12.0 15 0 0 15 15 13 3 HEAT repeat IBN_N PF03810.14 XP_011272543.1 - 1.7e-11 43.8 7.0 2.5e-11 43.3 2.6 3.2 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT_2 PF13646.1 XP_011272543.1 - 1.7e-09 37.8 9.3 0.0033 17.6 0.0 7.1 1 1 6 7 7 7 4 HEAT repeats CLASP_N PF12348.3 XP_011272543.1 - 0.00012 21.5 4.4 1.4 8.2 0.4 4.9 3 1 1 5 5 5 2 CLASP N terminal Vac14_Fab1_bd PF12755.2 XP_011272543.1 - 0.00065 20.0 0.2 5.7 7.3 0.0 5.4 4 1 2 6 6 6 1 Vacuolar 14 Fab1-binding region DUF1981 PF09324.5 XP_011272543.1 - 0.00091 18.7 3.3 0.17 11.4 0.0 5.0 4 2 1 5 5 5 1 Domain of unknown function (DUF1981) DUF3730 PF12530.3 XP_011272543.1 - 0.00096 19.1 2.8 0.13 12.1 0.8 3.7 2 1 0 2 2 2 1 Protein of unknown function (DUF3730) Cse1 PF08506.5 XP_011272543.1 - 0.0057 15.2 0.5 0.066 11.7 0.1 3.0 2 0 0 2 2 2 1 Cse1 RICTOR_V PF14668.1 XP_011272543.1 - 0.011 15.6 0.2 0.11 12.3 0.0 2.8 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, domain 5 Arm PF00514.18 XP_011272543.1 - 0.013 15.3 4.4 0.56 10.1 0.0 5.3 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat FMN_dh PF01070.13 XP_011272544.1 - 1.2e-91 307.2 0.0 1.4e-89 300.4 0.0 2.0 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 XP_011272544.1 - 6.7e-08 31.8 0.0 2.8e-07 29.8 0.0 1.9 2 0 0 2 2 2 1 Conserved region in glutamate synthase IMPDH PF00478.20 XP_011272544.1 - 1.3e-05 24.2 0.0 2.5e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 XP_011272544.1 - 0.00011 21.5 0.0 0.00016 20.9 0.0 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.9 XP_011272544.1 - 0.036 13.1 0.0 2.6 7.0 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 XP_011272544.1 - 0.056 12.7 0.7 0.66 9.2 0.1 2.3 1 1 1 2 2 2 0 Histidine biosynthesis protein APG6 PF04111.7 XP_011272545.1 - 0.005 15.9 8.6 0.005 15.9 5.9 1.5 2 0 0 2 2 2 1 Autophagy protein Apg6 PAP2 PF01569.16 XP_011272546.1 - 9.8e-19 67.3 1.0 1.7e-18 66.5 0.7 1.5 1 1 0 1 1 1 1 PAP2 superfamily 6PF2K PF01591.13 XP_011272547.1 - 8e-61 204.9 0.0 1.6e-60 203.9 0.0 1.5 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 XP_011272547.1 - 7.1e-18 65.1 0.0 1.5e-17 64.1 0.0 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 XP_011272547.1 - 0.00014 21.7 0.0 0.00031 20.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 XP_011272547.1 - 0.0065 16.7 0.1 0.024 14.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 XP_011272547.1 - 0.012 16.4 0.1 0.035 14.9 0.1 1.9 1 1 0 1 1 1 0 AAA domain KTI12 PF08433.5 XP_011272547.1 - 0.032 13.4 0.0 0.098 11.8 0.0 1.8 1 1 0 1 1 1 0 Chromatin associated protein KTI12 KOW PF00467.24 XP_011272548.1 - 0.00014 21.4 0.4 0.00014 21.4 0.3 1.8 2 0 0 2 2 2 1 KOW motif MCM PF00493.18 XP_011272549.1 - 2.4e-136 453.8 0.2 4.3e-136 453.0 0.2 1.4 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 XP_011272549.1 - 8.9e-21 74.6 0.5 8.9e-21 74.6 0.4 2.7 2 1 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 XP_011272549.1 - 5e-07 29.0 0.0 4e-06 26.1 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 XP_011272549.1 - 0.0011 18.5 0.0 0.0027 17.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 XP_011272549.1 - 0.0023 17.4 0.0 0.0055 16.2 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.9 XP_011272549.1 - 0.0097 15.6 0.0 0.026 14.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) TIM21 PF08294.6 XP_011272550.1 - 2.6e-51 173.1 0.0 3.4e-51 172.7 0.0 1.1 1 0 0 1 1 1 1 TIM21 MSC PF09402.5 XP_011272550.1 - 0.077 11.6 0.2 0.11 11.1 0.2 1.1 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain GUB_WAK_bind PF13947.1 XP_011272550.1 - 0.16 12.5 1.1 0.38 11.3 0.7 1.6 1 0 0 1 1 1 0 Wall-associated receptor kinase galacturonan-binding Glyco_hydro_72 PF03198.9 XP_011272551.1 - 1.3e-130 434.9 0.8 1.7e-130 434.5 0.6 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 XP_011272551.1 - 2.3e-18 66.4 0.2 6.1e-18 65.0 0.1 1.8 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.13 XP_011272551.1 - 0.0098 15.1 0.1 0.23 10.6 0.0 2.2 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Glucan_synthase PF02364.10 XP_011272552.1 - 0 1460.7 0.0 0 1459.9 0.0 1.4 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 XP_011272552.1 - 1.2e-39 134.8 0.1 3.2e-39 133.4 0.0 1.8 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 zf-Apc11 PF12861.2 XP_011272553.1 - 8.6e-43 144.1 8.9 1e-42 143.8 6.1 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 XP_011272553.1 - 6.8e-30 103.0 10.4 8.1e-30 102.7 7.2 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 XP_011272553.1 - 2.1e-07 30.6 14.6 4.9e-07 29.4 10.1 1.6 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 XP_011272553.1 - 0.0034 17.0 14.7 0.011 15.3 10.2 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 XP_011272553.1 - 0.0059 16.1 2.3 0.0059 16.1 1.6 2.4 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 XP_011272553.1 - 0.0062 16.1 13.7 0.11 12.1 9.6 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 XP_011272553.1 - 0.0084 15.8 13.2 0.057 13.1 9.3 2.0 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING-like PF08746.6 XP_011272553.1 - 0.012 15.6 8.1 0.012 15.6 5.6 1.6 2 0 0 2 2 2 0 RING-like domain zf-FCS PF06467.9 XP_011272553.1 - 0.015 14.9 2.4 0.3 10.7 0.0 2.6 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif FANCL_C PF11793.3 XP_011272553.1 - 0.019 14.9 9.6 0.05 13.5 6.6 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_2 PF13923.1 XP_011272553.1 - 0.025 14.6 14.0 0.14 12.1 9.7 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.9 XP_011272553.1 - 0.066 12.7 0.0 0.066 12.7 0.0 2.0 2 1 1 3 3 3 0 Rad50 zinc hook motif zf-HC5HC2H PF13771.1 XP_011272553.1 - 0.85 9.8 10.2 2.4 8.3 6.9 1.8 1 1 1 2 2 2 0 PHD-like zinc-binding domain zf-HIT PF04438.11 XP_011272553.1 - 4.8 6.9 9.0 1 9.0 2.7 2.2 2 0 0 2 2 2 0 HIT zinc finger CPL PF08144.6 XP_011272554.1 - 5.1e-22 78.3 0.1 8e-20 71.1 0.0 3.6 4 0 0 4 4 4 1 CPL (NUC119) domain PUF PF00806.14 XP_011272554.1 - 7.9e-05 21.9 5.8 5.3 6.7 0.0 6.0 6 0 0 6 6 6 2 Pumilio-family RNA binding repeat DUF4253 PF14062.1 XP_011272554.1 - 0.026 14.1 0.0 0.062 12.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4253) Daxx PF03344.10 XP_011272554.1 - 0.19 10.2 23.7 0.28 9.6 16.5 1.2 1 0 0 1 1 1 0 Daxx Family Dsh_C PF12316.3 XP_011272554.1 - 2.1 8.3 8.8 3.5 7.6 6.1 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Pkinase PF00069.20 XP_011272555.1 - 8.4e-73 244.7 0.2 2.6e-72 243.0 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011272555.1 - 5.1e-54 183.0 0.0 8.2e-54 182.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 XP_011272555.1 - 5.2e-06 25.6 0.0 1.2e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 XP_011272555.1 - 0.017 14.2 0.0 0.036 13.1 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CDC50 PF03381.10 XP_011272556.1 - 9e-94 313.7 0.4 1.2e-93 313.3 0.2 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family eRF1_2 PF03464.10 XP_011272557.1 - 1.1e-44 152.0 0.1 1.9e-44 151.2 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 XP_011272557.1 - 2.4e-36 124.4 0.2 4.9e-36 123.4 0.2 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 XP_011272557.1 - 1.2e-26 92.8 0.0 2.2e-26 92.0 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 Ribosomal_L7Ae PF01248.21 XP_011272557.1 - 0.012 15.0 0.0 0.029 13.8 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DEAD PF00270.24 XP_011272558.1 - 5.7e-39 133.3 0.1 1.8e-38 131.6 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 XP_011272558.1 - 3.7e-24 84.3 0.2 1.2e-22 79.5 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Nop14 PF04147.7 XP_011272558.1 - 5.4 4.7 41.1 0.015 13.2 19.5 2.4 2 0 0 2 2 2 0 Nop14-like family CotJB PF12652.2 XP_011272559.1 - 0.2 11.7 1.8 4.2 7.5 0.1 2.4 2 1 0 2 2 2 0 CotJB protein Methyltransf_31 PF13847.1 XP_011272561.1 - 2.7e-12 46.5 0.4 4.6e-12 45.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 XP_011272561.1 - 3e-11 43.8 0.0 9.3e-11 42.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 XP_011272561.1 - 3.8e-11 42.6 0.1 7.5e-11 41.6 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 XP_011272561.1 - 5.6e-10 39.2 0.0 1.5e-09 37.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain PRMT5 PF05185.11 XP_011272561.1 - 2.2e-09 36.7 0.0 3e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_11 PF08241.7 XP_011272561.1 - 3e-08 34.0 0.0 8.4e-08 32.5 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.9 XP_011272561.1 - 1.8e-06 27.4 0.0 3.9e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 XP_011272561.1 - 2.7e-06 27.2 0.0 5.2e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 XP_011272561.1 - 8.8e-06 24.6 0.1 1.3e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_25 PF13649.1 XP_011272561.1 - 9.5e-06 25.9 0.0 0.00016 21.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_16 PF10294.4 XP_011272561.1 - 2.9e-05 23.6 0.0 5e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase CMAS PF02353.15 XP_011272561.1 - 0.00014 20.9 0.0 0.00021 20.4 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 XP_011272561.1 - 0.00064 19.7 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase TehB PF03848.9 XP_011272561.1 - 0.0011 18.1 0.5 0.0026 16.9 0.0 1.9 3 0 0 3 3 3 1 Tellurite resistance protein TehB Ubie_methyltran PF01209.13 XP_011272561.1 - 0.013 14.5 0.0 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 XP_011272561.1 - 0.014 15.8 0.0 0.036 14.5 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.10 XP_011272561.1 - 0.022 14.1 0.0 0.036 13.4 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 UPF0020 PF01170.13 XP_011272561.1 - 0.039 13.5 0.0 0.071 12.6 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 PCMT PF01135.14 XP_011272561.1 - 0.048 13.2 0.0 0.087 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 XP_011272561.1 - 0.073 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.13 XP_011272561.1 - 0.077 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase PAS PF00989.19 XP_011272562.1 - 0.012 15.3 0.1 0.1 12.3 0.0 2.4 2 0 0 2 2 2 0 PAS fold Zn_clus PF00172.13 XP_011272562.1 - 0.044 13.6 1.3 0.078 12.8 0.9 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2HC5 PF06221.8 XP_011272563.1 - 9.3e-22 76.5 6.6 1.6e-21 75.7 4.5 1.4 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type zf-ribbon_3 PF13248.1 XP_011272563.1 - 0.55 9.5 5.4 1.1 8.6 3.7 1.5 1 0 0 1 1 1 0 zinc-ribbon domain zf-CCCH PF00642.19 XP_011272564.1 - 0.56 9.9 6.8 0.14 11.8 1.3 2.2 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Pam16 PF03656.8 XP_011272565.1 - 3e-36 124.0 2.5 3.5e-36 123.7 1.7 1.0 1 0 0 1 1 1 1 Pam16 HTH_37 PF13744.1 XP_011272565.1 - 0.03 14.1 0.1 0.069 12.9 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain ArfGap PF01412.13 XP_011272565.1 - 0.16 11.7 1.6 0.18 11.6 0.5 1.5 1 1 1 2 2 2 0 Putative GTPase activating protein for Arf PHD PF00628.24 XP_011272566.1 - 5.1e-10 38.8 7.3 1e-09 37.9 5.1 1.5 1 0 0 1 1 1 1 PHD-finger SET PF00856.23 XP_011272566.1 - 1e-09 38.8 0.0 1e-09 38.8 0.0 4.3 2 2 0 2 2 2 1 SET domain Pkinase PF00069.20 XP_011272567.1 - 1.5e-52 178.2 0.3 2.9e-51 174.1 0.2 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011272567.1 - 1.6e-25 89.6 0.3 1.9e-24 86.1 0.1 2.4 2 1 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 XP_011272567.1 - 0.04 12.9 0.1 0.067 12.2 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1212 PF06738.7 XP_011272569.1 - 1.7e-52 177.7 14.8 5.4e-49 166.2 0.1 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 XP_011272569.1 - 2.8e-27 95.2 12.1 2.8e-27 95.2 8.4 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3815) BP28CT PF08146.7 XP_011272570.1 - 5.3e-39 133.3 9.4 1.8e-38 131.6 3.1 3.9 3 0 0 3 3 3 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 XP_011272570.1 - 1.9e-14 53.6 1.9 1.9e-14 53.6 1.3 6.1 9 0 0 9 9 9 1 U3 small nucleolar RNA-associated protein 10 HEAT_2 PF13646.1 XP_011272570.1 - 0.0029 17.8 5.7 3.3 8.0 0.0 5.5 5 1 1 6 6 6 2 HEAT repeats HEAT_EZ PF13513.1 XP_011272570.1 - 0.0092 16.4 4.4 1.2 9.7 0.0 4.7 5 0 0 5 5 5 1 HEAT-like repeat HEAT PF02985.17 XP_011272570.1 - 2.2 8.6 5.2 51 4.3 0.2 5.0 5 0 0 5 5 5 0 HEAT repeat UNC-50 PF05216.8 XP_011272571.1 - 1.8e-95 318.5 20.7 2.1e-95 318.3 14.3 1.0 1 0 0 1 1 1 1 UNC-50 family RAP1 PF07218.6 XP_011272572.1 - 0.11 10.5 0.8 0.13 10.3 0.5 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) AHS1 PF02682.11 XP_011272573.1 - 0.078 12.4 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Allophanate hydrolase subunit 1 PLDc PF00614.17 XP_011272576.1 - 3.3e-18 64.8 0.9 2.9e-08 33.2 0.2 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 XP_011272576.1 - 4.4e-11 42.6 0.4 2.5e-07 30.5 0.1 2.8 2 1 0 2 2 2 2 PLD-like domain PX PF00787.19 XP_011272576.1 - 0.00012 21.8 3.4 0.00039 20.1 0.3 3.2 3 1 0 3 3 3 1 PX domain SNF2_N PF00176.18 XP_011272577.1 - 8.4e-48 162.6 1.4 1.6e-47 161.7 1.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4_3 PF13920.1 XP_011272577.1 - 5.1e-08 32.4 8.1 1.1e-07 31.3 5.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 XP_011272577.1 - 1.3e-07 31.2 10.1 2.6e-07 30.3 7.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 XP_011272577.1 - 2.5e-07 30.2 9.5 5.4e-07 29.1 6.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 XP_011272577.1 - 1.6e-05 24.4 9.3 3.2e-05 23.5 6.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 XP_011272577.1 - 4.9e-05 23.2 12.4 5.7e-05 23.0 7.7 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 XP_011272577.1 - 0.00011 21.6 5.4 0.00025 20.5 3.7 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Helicase_C PF00271.26 XP_011272577.1 - 0.0002 21.1 0.0 0.0018 18.0 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-rbx1 PF12678.2 XP_011272577.1 - 0.00066 19.7 8.2 0.0023 17.9 5.7 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 XP_011272577.1 - 0.0027 17.3 5.4 0.026 14.2 3.6 2.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.1 XP_011272577.1 - 0.013 15.1 5.2 0.037 13.6 3.6 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 XP_011272577.1 - 0.053 13.3 1.5 0.11 12.3 1.1 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 XP_011272577.1 - 0.66 9.8 7.9 1.8 8.5 5.5 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Pkinase PF00069.20 XP_011272578.1 - 1e-68 231.3 0.0 1e-68 231.3 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011272578.1 - 1.9e-31 109.1 0.0 5.1e-31 107.6 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 XP_011272578.1 - 0.0016 17.5 1.4 0.02 13.9 0.0 2.3 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3733 PF12534.3 XP_011272578.1 - 0.32 10.3 2.5 0.55 9.5 0.0 2.4 2 0 0 2 2 2 0 Leucine-rich repeat containing protein 8 TFIIA PF03153.8 XP_011272578.1 - 3.2 7.5 20.7 0.22 11.3 8.6 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit LIN37 PF15306.1 XP_011272579.1 - 0.1 12.5 0.7 0.2 11.6 0.5 1.4 1 1 0 1 1 1 0 LIN37 3Beta_HSD PF01073.14 XP_011272580.1 - 1.3e-11 43.7 0.0 1.9e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 XP_011272580.1 - 6.7e-11 42.0 0.0 9e-11 41.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 XP_011272580.1 - 2.2e-09 36.6 0.0 0.00013 20.9 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein NmrA PF05368.8 XP_011272580.1 - 3e-05 23.4 0.1 0.00014 21.1 0.0 1.9 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.20 XP_011272580.1 - 3.5e-05 23.7 0.0 6.3e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 XP_011272580.1 - 4.2e-05 23.6 0.0 7.8e-05 22.7 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 XP_011272580.1 - 0.008 15.1 0.1 0.016 14.1 0.1 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF4363 PF14276.1 XP_011272580.1 - 0.018 14.7 2.3 0.057 13.1 1.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) RmlD_sub_bind PF04321.12 XP_011272580.1 - 0.044 12.6 0.0 0.063 12.1 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Shikimate_DH PF01488.15 XP_011272580.1 - 0.056 13.5 0.1 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Bac_luciferase PF00296.15 XP_011272581.1 - 3.2e-51 174.2 0.0 4.6e-51 173.7 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase ADH_zinc_N PF00107.21 XP_011272582.1 - 6.3e-11 41.9 0.0 1.1e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 XP_011272582.1 - 3.8e-08 33.0 0.0 6.9e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Swi3 PF07962.7 XP_011272583.1 - 8.2e-21 73.4 0.3 1.4e-20 72.6 0.2 1.4 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 TFIIF_alpha PF05793.7 XP_011272583.1 - 0.057 11.7 31.1 0.091 11.1 21.6 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Hap4_Hap_bind PF10297.4 XP_011272584.1 - 4.1e-09 35.9 7.7 6.7e-09 35.2 5.3 1.4 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 MMR_HSR1 PF01926.18 XP_011272585.1 - 1.9e-15 56.8 0.6 4.1e-14 52.5 0.2 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 XP_011272585.1 - 1.8e-06 27.3 0.2 4.9e-06 25.9 0.1 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 XP_011272585.1 - 6.9e-06 25.3 0.0 1.6e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 IIGP PF05049.8 XP_011272585.1 - 0.00025 19.9 0.0 0.00051 18.9 0.0 1.5 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) ArgK PF03308.11 XP_011272585.1 - 0.005 15.6 0.0 0.0084 14.9 0.0 1.3 1 0 0 1 1 1 1 ArgK protein NTPase_1 PF03266.10 XP_011272585.1 - 0.0086 15.8 0.3 0.028 14.1 0.2 2.0 1 1 0 1 1 1 1 NTPase AAA_18 PF13238.1 XP_011272585.1 - 0.021 15.1 0.6 0.13 12.6 0.0 2.5 3 0 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.13 XP_011272585.1 - 0.038 13.4 0.0 0.32 10.4 0.0 2.3 3 0 0 3 3 3 0 FtsK/SpoIIIE family AIG1 PF04548.11 XP_011272585.1 - 0.057 12.5 0.2 0.057 12.5 0.2 2.4 3 0 0 3 3 3 0 AIG1 family AAA_14 PF13173.1 XP_011272585.1 - 0.064 13.1 0.5 0.3 11.0 0.1 2.2 2 0 0 2 2 2 0 AAA domain Sep15_SelM PF08806.6 XP_011272585.1 - 0.074 12.8 0.1 0.37 10.5 0.0 2.1 2 0 0 2 2 2 0 Sep15/SelM redox domain AAA_17 PF13207.1 XP_011272585.1 - 0.11 13.3 0.4 0.37 11.6 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 XP_011272585.1 - 0.13 11.8 0.0 0.31 10.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.1 XP_011272585.1 - 0.15 12.0 0.3 0.28 11.1 0.2 1.5 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 XP_011272586.1 - 1.9e-92 309.2 0.0 2.2e-92 309.0 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 XP_011272586.1 - 2e-07 30.9 0.0 3.7e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.15 XP_011272586.1 - 0.00029 20.5 0.0 0.00048 19.8 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_17 PF13207.1 XP_011272586.1 - 0.0003 21.6 0.0 0.00089 20.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 XP_011272586.1 - 0.0005 20.3 0.0 0.0012 19.1 0.0 1.6 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 XP_011272586.1 - 0.0051 16.7 0.0 0.063 13.2 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase Oligomerisation PF02410.10 XP_011272587.1 - 1.1e-19 70.2 0.0 2.6e-19 69.0 0.0 1.7 1 0 0 1 1 1 1 Oligomerisation domain mRNA_stabil PF13929.1 XP_011272587.1 - 2.6e-10 39.7 8.4 6.7e-10 38.3 5.9 1.7 1 1 0 1 1 1 1 mRNA stabilisation Drc1-Sld2 PF11719.3 XP_011272588.1 - 2e-42 145.8 30.4 8.1e-32 110.8 15.1 2.2 1 1 1 2 2 2 2 DNA replication and checkpoint protein YL1 PF05764.8 XP_011272588.1 - 3.3 7.2 23.4 7.7 6.0 16.1 1.8 1 1 0 1 1 1 0 YL1 nuclear protein BEX PF04538.7 XP_011272588.1 - 6.2 7.0 21.5 2.4 8.4 5.8 3.2 2 1 1 3 3 3 0 Brain expressed X-linked like family UTP15_C PF09384.5 XP_011272589.1 - 6.9e-51 171.8 0.2 1.1e-50 171.1 0.1 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 XP_011272589.1 - 1.1e-17 63.1 5.2 3.4e-05 23.5 0.0 6.9 6 1 0 6 6 6 4 WD domain, G-beta repeat WD40 PF00400.27 XP_011272590.1 - 3e-46 153.6 11.2 1.6e-06 27.7 0.0 11.0 11 0 0 11 11 11 8 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 XP_011272590.1 - 1.8e-05 23.7 1.8 0.035 12.9 0.2 2.8 2 1 0 2 2 2 2 Coatomer WD associated region PQQ_2 PF13360.1 XP_011272590.1 - 9.7e-05 21.9 4.1 0.13 11.6 0.8 3.2 2 1 1 3 3 3 2 PQQ-like domain BBS2_N PF14781.1 XP_011272590.1 - 0.029 14.0 0.5 0.42 10.2 0.1 3.0 2 1 0 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal Utp11 PF03998.8 XP_011272591.1 - 6.2e-71 239.0 38.9 7e-71 238.8 27.0 1.0 1 0 0 1 1 1 1 Utp11 protein Ku PF02735.11 XP_011272593.1 - 1.4e-24 86.6 0.1 2.3e-24 85.9 0.1 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Macro_2 PF14519.1 XP_011272594.1 - 1.8e-14 53.5 0.0 2.3e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Macro-like domain Macro PF01661.16 XP_011272594.1 - 0.08 12.8 0.0 0.36 10.7 0.0 2.0 1 1 0 1 1 1 0 Macro domain DUF2454 PF10521.4 XP_011272595.1 - 1.8e-52 178.1 6.1 3.1e-52 177.3 4.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) MFS_1 PF07690.11 XP_011272596.1 - 3.4e-19 68.7 43.3 1.8e-13 49.9 8.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MRP-L28 PF09812.4 XP_011272597.1 - 3.9e-31 108.0 0.6 4.7e-31 107.7 0.4 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 RdRP_2 PF00978.16 XP_011272597.1 - 0.074 11.7 0.7 0.087 11.4 0.5 1.0 1 0 0 1 1 1 0 RNA dependent RNA polymerase Syntaxin-6_N PF09177.6 XP_011272597.1 - 0.11 12.9 1.0 1.7 9.0 0.2 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal ATG2_CAD PF13329.1 XP_011272599.1 - 2.6e-36 124.5 8.6 2.7e-36 124.5 3.4 3.2 2 0 0 2 2 2 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.6 XP_011272599.1 - 1.6e-29 101.8 0.0 5.3e-29 100.2 0.0 2.0 1 0 0 1 1 1 1 ATG C terminal domain Aminotran_1_2 PF00155.16 XP_011272600.1 - 1.3e-26 93.4 0.0 1.5e-26 93.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 XP_011272600.1 - 8.3e-05 21.7 0.0 0.00013 21.1 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_MocR PF12897.2 XP_011272600.1 - 0.00012 20.7 0.0 0.001 17.6 0.0 1.9 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase SCP2 PF02036.12 XP_011272601.1 - 1.4e-16 60.6 2.2 1.6e-16 60.4 1.5 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 XP_011272601.1 - 8e-05 22.6 0.8 0.0001 22.2 0.6 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal ELFV_dehydrog PF00208.16 XP_011272602.1 - 4.9e-56 190.0 0.0 7.7e-56 189.3 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 XP_011272602.1 - 5.4e-23 80.4 2.0 1e-14 53.0 0.0 2.5 3 0 0 3 3 3 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 XP_011272602.1 - 0.0023 17.4 0.0 0.013 15.0 0.0 2.1 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ARL2_Bind_BART PF11527.3 XP_011272602.1 - 0.81 9.4 9.4 0.076 12.8 1.1 3.2 3 0 0 3 3 3 0 The ARF-like 2 binding protein BART Sod_Cu PF00080.15 XP_011272603.1 - 2.1e-19 70.0 0.6 2.9e-19 69.6 0.4 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) CHRD PF07452.7 XP_011272603.1 - 0.021 15.4 0.0 0.053 14.1 0.0 1.6 1 0 0 1 1 1 0 CHRD domain DUF2441 PF10386.4 XP_011272604.1 - 0.02 14.9 0.1 0.044 13.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2441) Sod_Cu PF00080.15 XP_011272605.1 - 8.5e-20 71.3 0.7 1.3e-19 70.7 0.0 1.6 2 0 0 2 2 2 1 Copper/zinc superoxide dismutase (SODC) CDC45 PF02724.9 XP_011272605.1 - 1.5 6.8 10.2 1.9 6.3 7.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Astro_capsid PF03115.9 XP_011272605.1 - 1.6 6.9 7.0 2.1 6.5 4.9 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Fe-S_biosyn PF01521.15 XP_011272606.1 - 5.3e-19 68.2 0.0 8e-19 67.6 0.0 1.3 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Neur_chan_memb PF02932.11 XP_011272606.1 - 1.3 8.9 6.9 1.7 8.4 4.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Suf PF05843.9 XP_011272606.1 - 5.8 6.5 9.7 8.1 6.0 6.7 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Peptidase_M24 PF00557.19 XP_011272607.1 - 7.8e-36 123.5 0.0 1.2e-35 123.0 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 XP_011272607.1 - 2e-15 57.4 0.0 8.9e-12 45.6 0.0 2.3 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain UCH PF00443.24 XP_011272609.1 - 3.1e-60 203.5 4.2 3.9e-60 203.2 2.9 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 XP_011272609.1 - 1.4e-26 93.6 7.0 2.1e-26 93.0 4.9 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 XP_011272609.1 - 0.36 10.0 8.3 5.2 6.2 3.2 3.2 2 1 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase zf-UBP PF02148.14 XP_011272610.1 - 3.3e-07 30.3 6.5 7e-07 29.2 4.5 1.5 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein CIAPIN1 PF05093.8 XP_011272610.1 - 0.0072 16.3 0.1 0.0097 15.9 0.1 1.3 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis zf-UBR PF02207.15 XP_011272610.1 - 0.2 11.4 4.5 0.33 10.6 3.1 1.3 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) zf-RING_5 PF14634.1 XP_011272610.1 - 5.2 6.8 9.8 7.3 6.4 4.5 2.2 2 0 0 2 2 2 0 zinc-RING finger domain DUF592 PF04574.8 XP_011272611.1 - 0.058 12.9 0.2 0.1 12.1 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF592) MFS_1 PF07690.11 XP_011272612.1 - 8.2e-22 77.3 15.4 8.2e-22 77.3 10.7 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 XP_011272612.1 - 4e-05 23.3 1.0 0.00018 21.2 0.4 2.3 2 0 0 2 2 2 1 MFS_1 like family DUF4233 PF14017.1 XP_011272612.1 - 7.2 6.5 10.5 0.24 11.3 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4233) Zn_clus PF00172.13 XP_011272613.1 - 0.013 15.3 1.4 0.025 14.4 0.9 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Kinesin-related PF06548.6 XP_011272613.1 - 0.028 12.9 0.2 0.055 12.0 0.1 1.5 1 0 0 1 1 1 0 Kinesin-related Fungal_trans PF04082.13 XP_011272614.1 - 2.7e-08 33.0 2.7 3.7e-08 32.5 0.1 2.4 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 XP_011272614.1 - 7.1e-08 32.2 10.6 7.1e-08 32.2 7.4 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 XP_011272615.1 - 2e-08 33.4 0.1 4.5e-08 32.2 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain FliL PF03748.9 XP_011272615.1 - 0.052 13.5 0.2 7.6 6.5 0.0 2.6 2 0 0 2 2 2 0 Flagellar basal body-associated protein FliL Fungal_trans PF04082.13 XP_011272616.1 - 4.2e-20 71.7 8.8 2.9e-11 42.7 0.6 2.9 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 XP_011272616.1 - 0.0006 19.6 5.0 0.34 10.8 0.2 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 XP_011272617.1 - 2.1e-10 39.9 2.1 4.4e-10 38.8 1.4 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 XP_011272617.1 - 1.2e-07 31.4 10.1 2.4e-07 30.5 7.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cellulase PF00150.13 XP_011272618.1 - 6.6e-18 64.9 8.8 1.1e-17 64.1 6.1 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF4434 PF14488.1 XP_011272618.1 - 0.0018 18.0 0.0 0.0052 16.5 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4434) Cellulase-like PF12876.2 XP_011272618.1 - 0.011 16.2 0.2 0.032 14.6 0.1 1.8 1 0 0 1 1 1 0 Sugar-binding cellulase-like DSPn PF14671.1 XP_011272619.1 - 2.2e-49 167.0 0.0 1.5e-48 164.4 0.0 2.2 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 XP_011272619.1 - 1.2e-22 79.8 1.2 4.5e-22 78.0 0.0 2.4 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 XP_011272619.1 - 1.1e-05 24.8 0.0 1.1e-05 24.8 0.0 2.2 3 0 0 3 3 3 1 Protein-tyrosine phosphatase CDKN3 PF05706.7 XP_011272619.1 - 0.0022 17.4 0.4 0.018 14.5 0.1 2.4 3 0 0 3 3 3 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.1 XP_011272619.1 - 0.0041 17.1 0.2 0.035 14.1 0.0 2.2 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 XP_011272619.1 - 0.29 11.3 1.8 0.38 10.9 0.0 2.2 2 1 0 2 2 2 0 Tyrosine phosphatase family Pyr_redox_2 PF07992.9 XP_011272620.1 - 5.3e-27 95.0 0.0 8e-27 94.4 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 XP_011272620.1 - 2.4e-17 63.1 0.4 4.1e-14 52.7 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 XP_011272620.1 - 2.6e-10 40.7 0.0 1.7e-07 31.5 0.0 2.2 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 XP_011272620.1 - 2e-07 30.2 1.0 0.042 12.7 0.0 3.2 3 0 0 3 3 3 3 FAD dependent oxidoreductase GIDA PF01134.17 XP_011272620.1 - 5.3e-06 25.5 2.7 0.34 9.7 0.0 4.1 4 1 1 5 5 5 2 Glucose inhibited division protein A NAD_binding_7 PF13241.1 XP_011272620.1 - 8.2e-05 22.8 0.1 0.029 14.6 0.0 2.4 2 1 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_8 PF13450.1 XP_011272620.1 - 0.00015 21.6 0.1 0.0069 16.3 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 XP_011272620.1 - 0.0002 20.5 0.4 0.0014 17.7 0.0 2.2 2 1 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 XP_011272620.1 - 0.00089 17.8 0.1 0.56 8.6 0.0 3.1 3 1 0 4 4 4 2 HI0933-like protein FAD_binding_3 PF01494.14 XP_011272620.1 - 0.001 18.2 0.0 0.15 11.1 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 XP_011272620.1 - 0.005 16.6 0.1 2.4 7.9 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding Shikimate_DH PF01488.15 XP_011272620.1 - 0.0063 16.6 0.2 2.5 8.2 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 XP_011272620.1 - 0.016 14.0 3.5 1.4 7.6 0.3 3.0 2 2 2 4 4 4 0 FAD binding domain K_oxygenase PF13434.1 XP_011272620.1 - 0.046 12.6 0.0 0.75 8.6 0.0 2.6 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Septin PF00735.13 XP_011272621.1 - 2.7e-113 377.6 0.1 4.2e-113 377.0 0.1 1.3 1 0 0 1 1 1 1 Septin DUF258 PF03193.11 XP_011272621.1 - 4.2e-08 32.5 0.5 9.8e-08 31.3 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 XP_011272621.1 - 3.5e-06 26.9 0.0 7.5e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 XP_011272621.1 - 0.001 18.5 0.6 0.008 15.6 0.0 2.5 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.13 XP_011272621.1 - 0.0022 17.5 0.1 0.0062 16.0 0.0 1.8 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_22 PF13401.1 XP_011272621.1 - 0.0023 18.0 0.3 0.0074 16.4 0.0 1.9 2 1 0 2 2 2 1 AAA domain NACHT PF05729.7 XP_011272621.1 - 0.01 15.5 0.1 0.026 14.1 0.0 1.8 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 XP_011272621.1 - 0.012 15.6 1.0 0.039 13.9 0.1 2.4 2 1 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.1 XP_011272621.1 - 0.024 14.2 0.0 0.052 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 XP_011272621.1 - 0.03 14.4 0.0 0.093 12.9 0.0 1.8 1 1 0 1 1 1 0 RNA helicase Miro PF08477.8 XP_011272621.1 - 0.045 14.2 0.0 0.15 12.5 0.0 2.0 1 0 0 1 1 1 0 Miro-like protein Dynamin_N PF00350.18 XP_011272621.1 - 0.055 13.2 6.4 3.1 7.6 0.0 3.3 2 1 1 3 3 3 0 Dynamin family PRK PF00485.13 XP_011272621.1 - 0.069 12.7 0.2 0.25 10.8 0.0 1.9 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family MobB PF03205.9 XP_011272621.1 - 0.11 12.2 0.0 0.26 10.9 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 XP_011272621.1 - 0.11 12.7 0.8 0.48 10.7 0.0 2.3 2 0 0 2 2 2 0 ABC transporter AAA_14 PF13173.1 XP_011272621.1 - 0.17 11.7 1.9 1.3 8.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 XP_011272621.1 - 0.18 10.5 1.7 2 7.1 0.0 2.3 2 0 0 2 2 2 0 ArgK protein Osmo_CC PF08946.5 XP_011272621.1 - 0.69 9.9 6.4 0.15 12.1 1.3 2.2 2 0 0 2 2 2 0 Osmosensory transporter coiled coil Glycos_transf_3 PF00591.16 XP_011272622.1 - 2e-84 282.9 0.0 2.4e-84 282.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 XP_011272622.1 - 1.3e-13 50.3 0.0 1.1e-12 47.3 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain RTX PF02382.10 XP_011272622.1 - 0.0041 15.4 0.1 0.047 11.9 0.0 2.2 2 0 0 2 2 2 1 RTX N-terminal domain DUF904 PF06005.7 XP_011272623.1 - 3.8e-05 23.8 6.0 3.8e-05 23.8 4.2 14.0 3 2 5 9 9 9 3 Protein of unknown function (DUF904) Phage_GP20 PF06810.6 XP_011272623.1 - 0.0046 16.3 9.8 0.0046 16.3 6.8 10.3 1 1 10 11 11 11 3 Phage minor structural protein GP20 HrpB7 PF09486.5 XP_011272623.1 - 0.45 10.4 32.4 0.43 10.5 0.4 5.9 2 1 0 4 4 4 0 Bacterial type III secretion protein (HrpB7) HSDR_N PF04313.9 XP_011272624.1 - 0.0085 15.8 1.0 0.01 15.5 0.7 1.1 1 0 0 1 1 1 1 Type I restriction enzyme R protein N terminus (HSDR_N) DUF2365 PF10157.4 XP_011272624.1 - 0.057 13.2 1.2 0.079 12.8 0.8 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2365) Syntaxin PF00804.20 XP_011272624.1 - 4.4 7.5 7.2 11 6.1 3.1 2.5 1 1 1 2 2 2 0 Syntaxin VHS PF00790.14 XP_011272625.1 - 4.8e-27 94.3 0.1 2.7e-26 91.9 0.0 2.2 2 0 0 2 2 2 1 VHS domain Alpha_adaptinC2 PF02883.15 XP_011272625.1 - 7.6e-17 61.6 0.3 7.6e-17 61.6 0.2 2.6 2 1 1 3 3 3 1 Adaptin C-terminal domain GAT PF03127.9 XP_011272625.1 - 2.4e-16 59.5 3.3 7.4e-16 57.9 2.3 1.9 1 0 0 1 1 1 1 GAT domain HSA PF07529.8 XP_011272626.1 - 2.6e-19 68.7 0.0 2.6e-19 68.7 0.0 2.7 2 0 0 2 2 2 1 HSA Myb_DNA-bind_6 PF13921.1 XP_011272626.1 - 1.1e-08 35.0 0.4 5.7e-08 32.7 0.3 2.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 XP_011272626.1 - 0.065 13.2 1.4 0.28 11.2 0.0 2.5 2 0 0 2 2 2 0 Myb-like DNA-binding domain zf-CCCH PF00642.19 XP_011272627.1 - 1.5e-08 34.0 1.9 0.00074 19.1 0.1 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF1771 PF08590.5 XP_011272627.1 - 2.1e-05 24.4 2.6 5e-05 23.2 1.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) DDE_Tnp_ISAZ013 PF07592.6 XP_011272627.1 - 0.0025 16.6 1.2 0.0028 16.4 0.0 1.6 2 0 0 2 2 2 1 Rhodopirellula transposase DDE domain UBA PF00627.26 XP_011272627.1 - 0.022 14.6 0.1 0.28 11.0 0.0 2.8 3 0 0 3 3 3 0 UBA/TS-N domain SSP160 PF06933.6 XP_011272627.1 - 0.072 11.0 6.7 0.12 10.3 4.6 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 zf-CCCH_2 PF14608.1 XP_011272627.1 - 2.7 8.1 8.0 0.27 11.3 1.0 2.7 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type BCIP PF13862.1 XP_011272628.1 - 1e-44 152.4 5.0 1.4e-44 151.9 3.5 1.2 1 0 0 1 1 1 1 p21-C-terminal region-binding protein Jnk-SapK_ap_N PF09744.4 XP_011272628.1 - 0.0055 16.7 0.3 0.0055 16.7 0.2 2.3 2 1 1 3 3 3 1 JNK_SAPK-associated protein-1 TLP-20 PF06088.6 XP_011272628.1 - 6.5 6.4 13.0 0.27 10.8 1.7 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) PP1c_bdg PF10488.4 XP_011272628.1 - 8.2 5.5 8.4 43 3.1 0.0 2.2 2 0 0 2 2 2 0 Phosphatase-1 catalytic subunit binding region WD40 PF00400.27 XP_011272629.1 - 2.5e-31 106.4 7.4 8.4e-08 31.8 0.0 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 XP_011272629.1 - 4.9e-05 21.6 0.0 0.049 11.7 0.0 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.9 XP_011272629.1 - 0.041 12.6 3.9 0.061 12.1 0.7 2.2 1 1 1 2 2 2 0 Coatomer WD associated region AAA PF00004.24 XP_011272630.1 - 2.2e-40 137.9 0.0 4.1e-40 137.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 XP_011272630.1 - 4.3e-05 23.4 0.0 0.00014 21.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 XP_011272630.1 - 0.00015 21.8 2.7 0.012 15.6 0.0 3.0 2 2 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.7 XP_011272630.1 - 0.00054 19.0 0.0 0.0013 17.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 XP_011272630.1 - 0.00058 19.9 1.2 0.0094 16.0 0.1 2.8 2 1 0 2 2 1 1 AAA domain AAA_33 PF13671.1 XP_011272630.1 - 0.0015 18.4 0.1 0.014 15.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 XP_011272630.1 - 0.0022 17.7 1.9 0.0074 16.0 0.1 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) PhoH PF02562.11 XP_011272630.1 - 0.0046 16.2 0.1 0.025 13.8 0.0 2.0 2 0 0 2 2 2 1 PhoH-like protein DUF815 PF05673.8 XP_011272630.1 - 0.0074 15.2 0.1 0.019 13.8 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.16 XP_011272630.1 - 0.012 14.8 0.2 0.029 13.5 0.1 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 XP_011272630.1 - 0.014 15.1 0.1 0.038 13.7 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 XP_011272630.1 - 0.015 14.7 0.0 0.028 13.8 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.1 XP_011272630.1 - 0.029 14.2 0.8 0.1 12.5 0.0 2.2 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.1 XP_011272630.1 - 0.032 15.0 0.8 0.2 12.5 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.1 XP_011272630.1 - 0.044 13.3 0.1 0.13 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 XP_011272630.1 - 0.048 13.0 0.7 0.5 9.7 0.1 2.3 1 1 1 2 2 2 0 AAA domain ThylakoidFormat PF11264.3 XP_011272630.1 - 0.049 13.2 5.5 0.11 12.0 3.8 1.6 1 0 0 1 1 1 0 Thylakoid formation protein Zeta_toxin PF06414.7 XP_011272630.1 - 0.066 12.3 1.1 0.21 10.6 0.1 2.1 2 1 0 2 2 2 0 Zeta toxin Sigma54_activat PF00158.21 XP_011272630.1 - 0.089 12.2 0.0 0.28 10.6 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain KaiC PF06745.8 XP_011272630.1 - 0.16 11.0 1.5 0.29 10.2 0.0 2.2 3 0 0 3 3 3 0 KaiC adh_short PF00106.20 XP_011272631.1 - 7e-21 74.8 0.0 8.6e-21 74.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 XP_011272631.1 - 4.7e-16 59.3 0.0 6e-16 58.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 XP_011272631.1 - 4.2e-12 46.1 0.0 5.9e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 XP_011272631.1 - 1.7e-06 28.1 0.0 3.3e-06 27.2 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 XP_011272631.1 - 0.00013 21.5 0.1 0.00022 20.7 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 XP_011272631.1 - 0.0011 17.9 0.0 0.0018 17.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein ADH_zinc_N PF00107.21 XP_011272631.1 - 0.024 14.1 0.0 0.047 13.2 0.0 1.5 1 1 0 1 1 1 0 Zinc-binding dehydrogenase DUF1776 PF08643.5 XP_011272631.1 - 0.035 13.2 0.2 0.071 12.2 0.1 1.6 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) 3Beta_HSD PF01073.14 XP_011272631.1 - 0.041 12.5 0.0 0.057 12.1 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family PrpR_N PF06506.6 XP_011272631.1 - 0.057 12.8 0.2 0.091 12.1 0.1 1.3 1 0 0 1 1 1 0 Propionate catabolism activator Glyco_hydro_101 PF12905.2 XP_011272631.1 - 0.089 11.3 0.0 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 Endo-alpha-N-acetylgalactosaminidase HTH_WhiA PF02650.9 XP_011272631.1 - 0.13 12.6 0.2 10 6.6 0.0 2.4 2 0 0 2 2 2 0 WhiA C-terminal HTH domain ETRAMP PF09716.5 XP_011272631.1 - 1.2 9.1 4.0 14 5.6 2.8 2.3 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) MmgE_PrpD PF03972.9 XP_011272632.1 - 1.5e-160 534.2 0.0 1.9e-160 533.9 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Citrate_synt PF00285.16 XP_011272633.1 - 9.3e-95 317.3 0.0 1.1e-94 317.0 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase S-AdoMet_synt_C PF02773.11 XP_011272634.1 - 3.2e-75 250.4 0.4 5.8e-75 249.5 0.3 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 XP_011272634.1 - 5.5e-48 161.8 0.0 9.6e-48 161.0 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 XP_011272634.1 - 2.2e-42 143.3 0.1 4.7e-42 142.2 0.1 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain SNF2_N PF00176.18 XP_011272635.1 - 2.7e-82 275.9 1.8 7.4e-82 274.4 1.3 1.8 1 0 0 1 1 1 1 SNF2 family N-terminal domain Bromodomain PF00439.20 XP_011272635.1 - 1.5e-18 66.4 0.8 1.5e-18 66.4 0.5 3.2 3 0 0 3 3 3 1 Bromodomain Helicase_C PF00271.26 XP_011272635.1 - 5.6e-17 61.3 0.3 6.1e-16 58.0 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SnAC PF14619.1 XP_011272635.1 - 1e-13 51.2 4.9 1e-13 51.2 3.4 4.5 3 1 1 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex HSA PF07529.8 XP_011272635.1 - 0.00022 20.9 8.0 0.00022 20.9 5.5 2.6 2 0 0 2 2 2 1 HSA WWbp PF10349.4 XP_011272636.1 - 0.0059 17.4 0.0 0.014 16.2 0.0 1.6 1 0 0 1 1 1 1 WW-domain ligand protein bPH_3 PF14470.1 XP_011272636.1 - 0.017 15.3 0.0 0.026 14.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial PH domain TAFII55_N PF04658.8 XP_011272637.1 - 5.7e-42 142.9 1.3 5.7e-42 142.9 0.9 2.6 2 0 0 2 2 2 1 TAFII55 protein conserved region RrnaAD PF00398.15 XP_011272638.1 - 1.7e-25 89.5 0.0 1.8e-25 89.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PIN_4 PF13638.1 XP_011272639.1 - 4.8e-07 29.9 0.0 1.6e-06 28.2 0.0 1.8 1 1 0 1 1 1 1 PIN domain Septin PF00735.13 XP_011272640.1 - 3.2e-95 318.3 2.6 5.2e-95 317.6 1.8 1.3 1 0 0 1 1 1 1 Septin DUF258 PF03193.11 XP_011272640.1 - 1.3e-06 27.6 0.2 5e-06 25.7 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 XP_011272640.1 - 5.7e-06 26.2 0.0 1.7e-05 24.7 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 XP_011272640.1 - 8.9e-06 25.2 0.3 0.012 15.0 0.0 2.4 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.13 XP_011272640.1 - 0.012 15.1 0.0 0.026 13.9 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AIG1 PF04548.11 XP_011272640.1 - 0.019 14.1 0.0 0.019 14.1 0.0 2.3 2 1 1 3 3 3 0 AIG1 family AAA_16 PF13191.1 XP_011272640.1 - 0.02 14.8 0.0 0.046 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 XP_011272640.1 - 0.039 14.0 0.3 0.4 10.8 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_10 PF12846.2 XP_011272640.1 - 0.051 13.0 0.7 0.083 12.3 0.2 1.8 1 1 0 1 1 1 0 AAA-like domain AAA_29 PF13555.1 XP_011272640.1 - 0.14 11.7 0.1 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 XP_011272640.1 - 2.1 8.6 8.4 12 6.2 5.8 2.7 1 1 0 1 1 1 0 ABC transporter B12D PF06522.6 XP_011272641.1 - 0.3 10.8 1.6 0.62 9.8 1.1 1.6 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit EF-hand_1 PF00036.27 XP_011272642.1 - 2.2e-19 67.1 7.2 5.3e-06 25.3 0.1 4.9 4 1 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 XP_011272642.1 - 1.2e-15 55.8 7.8 0.0064 16.2 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.1 XP_011272642.1 - 3.3e-15 55.9 6.5 1.3e-08 34.7 0.8 3.3 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.1 XP_011272642.1 - 3e-13 49.1 6.1 8.1e-06 25.3 0.1 4.3 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 XP_011272642.1 - 1.6e-07 30.3 12.0 0.0041 16.4 0.0 4.7 4 1 0 4 4 4 3 EF hand EF-hand_10 PF14788.1 XP_011272642.1 - 0.15 11.7 0.1 1.3 8.7 0.0 2.3 2 0 0 2 2 2 0 EF hand AChE_tetra PF08674.5 XP_011272642.1 - 0.24 10.9 1.6 0.5 9.9 1.1 1.5 1 0 0 1 1 1 0 Acetylcholinesterase tetramerisation domain PAP1 PF08601.5 XP_011272642.1 - 3.7 7.1 8.1 5 6.7 5.6 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Ribosomal_S6e PF01092.14 XP_011272643.1 - 1.2e-62 209.1 0.6 2e-62 208.4 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein S6e Cadherin_C PF01049.12 XP_011272643.1 - 0.061 13.3 0.2 0.1 12.6 0.1 1.3 1 0 0 1 1 1 0 Cadherin cytoplasmic region S10_plectin PF03501.10 XP_011272644.1 - 2.1e-31 107.6 0.1 2.6e-31 107.3 0.1 1.0 1 0 0 1 1 1 1 Plectin/S10 domain Replic_Relax PF13814.1 XP_011272644.1 - 0.021 14.6 0.1 0.025 14.4 0.1 1.1 1 0 0 1 1 1 0 Replication-relaxation PadR PF03551.9 XP_011272644.1 - 0.041 13.6 0.5 0.071 12.8 0.4 1.5 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DUF2250 PF10007.4 XP_011272644.1 - 0.11 12.4 1.0 3 7.8 0.1 2.0 1 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) Mpv17_PMP22 PF04117.7 XP_011272645.1 - 2.8e-22 78.1 2.8 2.8e-22 78.1 1.9 3.8 4 0 0 4 4 4 2 Mpv17 / PMP22 family MNHE PF01899.11 XP_011272645.1 - 0.035 13.7 0.0 0.11 12.1 0.0 1.8 1 0 0 1 1 1 0 Na+/H+ ion antiporter subunit DUF912 PF06024.7 XP_011272645.1 - 0.041 13.9 0.4 0.13 12.2 0.3 1.9 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) YGGT PF02325.12 XP_011272646.1 - 0.0028 17.5 2.3 0.01 15.7 1.6 1.9 1 1 0 1 1 1 1 YGGT family DUF4134 PF13572.1 XP_011272646.1 - 0.58 10.3 3.7 0.16 12.1 0.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4134) PCI_Csn8 PF10075.4 XP_011272647.1 - 1.4e-08 34.5 0.1 2e-08 34.0 0.1 1.3 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 XP_011272647.1 - 1.3e-07 31.4 0.7 1.8e-07 30.9 0.5 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family S1 PF00575.18 XP_011272648.1 - 1.8e-69 229.7 40.4 3.8e-15 55.7 0.4 12.8 13 1 0 13 13 13 8 S1 RNA binding domain TPR_19 PF14559.1 XP_011272648.1 - 3.7e-06 27.1 0.0 0.66 10.3 0.0 4.2 4 1 1 5 5 5 2 Tetratricopeptide repeat Suf PF05843.9 XP_011272648.1 - 9.4e-05 22.2 2.0 9.4e-05 22.2 1.4 5.4 3 2 3 6 6 6 2 Suppressor of forked protein (Suf) Sigma70_ner PF04546.8 XP_011272648.1 - 0.0012 18.5 3.9 0.0012 18.5 2.7 3.7 2 1 0 2 2 2 1 Sigma-70, non-essential region TPR_15 PF13429.1 XP_011272648.1 - 0.0031 16.6 2.9 0.66 8.9 0.0 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 XP_011272648.1 - 0.0063 17.0 0.0 24 5.9 0.0 3.7 2 1 1 3 3 3 0 Tetratricopeptide repeat Nop14 PF04147.7 XP_011272648.1 - 0.1 10.4 44.8 0.036 11.9 18.5 2.3 2 0 0 2 2 2 0 Nop14-like family TPR_17 PF13431.1 XP_011272648.1 - 0.19 12.0 0.0 15 6.0 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat BRAP2 PF07576.7 XP_011272650.1 - 7.8e-27 93.0 1.1 2.5e-26 91.4 0.7 1.8 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.14 XP_011272650.1 - 2.8e-22 78.6 6.9 7.6e-22 77.2 4.8 1.8 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 XP_011272650.1 - 2.2e-09 36.9 10.4 2.2e-09 36.9 7.2 2.5 2 0 0 2 2 1 1 Ring finger domain zf-RING_5 PF14634.1 XP_011272650.1 - 2e-06 27.4 8.8 2e-06 27.4 6.1 2.5 2 1 1 3 3 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 XP_011272650.1 - 0.00011 21.8 10.1 0.00034 20.1 7.0 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 XP_011272650.1 - 0.00014 21.5 7.0 0.00014 21.5 4.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 XP_011272650.1 - 0.00025 21.0 9.6 0.00025 21.0 6.6 2.5 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 XP_011272650.1 - 0.0005 20.1 7.6 0.0005 20.1 5.3 2.5 1 1 0 2 2 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 XP_011272650.1 - 0.00073 19.3 3.7 0.0028 17.4 2.6 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 XP_011272650.1 - 0.0014 18.2 5.0 0.0025 17.4 2.0 2.5 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.1 XP_011272650.1 - 0.063 12.8 7.5 0.16 11.5 5.2 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RRM_1 PF00076.17 XP_011272650.1 - 0.09 12.4 0.2 0.36 10.5 0.1 2.1 2 0 0 2 2 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fe-S_assembly PF04384.8 XP_011272650.1 - 0.13 12.6 2.3 9.3 6.7 0.1 2.5 2 0 0 2 2 2 0 Iron-sulphur cluster assembly HALZ PF02183.13 XP_011272650.1 - 0.15 11.8 5.4 1.8 8.3 0.7 2.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper Phage_GPO PF05929.6 XP_011272650.1 - 0.16 11.2 12.5 0.32 10.2 3.4 2.2 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Reo_sigmaC PF04582.7 XP_011272650.1 - 0.18 10.9 3.3 0.38 9.8 2.3 1.6 1 0 0 1 1 1 0 Reovirus sigma C capsid protein IncA PF04156.9 XP_011272650.1 - 0.28 10.7 19.9 1.2 8.6 13.3 2.1 1 1 1 2 2 2 0 IncA protein MbeD_MobD PF04899.7 XP_011272650.1 - 0.3 11.0 9.2 0.17 11.7 2.6 2.5 2 0 0 2 2 2 0 MbeD/MobD like GP41 PF00517.12 XP_011272650.1 - 0.31 10.5 8.1 4 6.9 1.1 2.6 1 1 1 2 2 2 0 Retroviral envelope protein BLOC1_2 PF10046.4 XP_011272650.1 - 0.34 11.0 12.4 2 8.6 1.6 3.1 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TBCA PF02970.11 XP_011272650.1 - 0.39 10.8 15.4 0.21 11.6 2.3 3.2 2 1 1 3 3 3 0 Tubulin binding cofactor A DUF4200 PF13863.1 XP_011272650.1 - 0.59 10.0 17.5 0.44 10.5 5.0 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Erp_C PF06780.6 XP_011272650.1 - 0.73 9.6 10.9 2.9 7.7 0.7 2.6 1 1 1 2 2 2 0 Erp protein C-terminus Baculo_PEP_C PF04513.7 XP_011272650.1 - 0.78 9.5 9.6 0.065 13.0 1.3 2.5 2 1 1 3 3 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus zf-C3HC4_4 PF15227.1 XP_011272650.1 - 1.5 8.7 9.3 1.8 8.5 4.5 2.7 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING DUF4407 PF14362.1 XP_011272650.1 - 1.5 7.7 8.5 2 7.2 5.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Occludin_ELL PF07303.8 XP_011272650.1 - 1.7 9.3 9.2 5.8 7.7 3.8 3.4 2 1 0 2 2 2 0 Occludin homology domain UPF0184 PF03670.8 XP_011272650.1 - 3.1 8.0 8.0 0.56 10.4 2.2 2.3 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0184) DUF3450 PF11932.3 XP_011272650.1 - 4.2 6.5 14.4 0.43 9.7 2.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Pribosyl_synth PF14572.1 XP_011272651.1 - 5.9e-43 146.7 1.5 6.7e-37 127.0 0.5 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 XP_011272651.1 - 2.1e-40 137.0 1.1 1.3e-39 134.4 0.1 2.1 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 XP_011272651.1 - 1.1e-11 44.5 1.0 6.5e-11 42.0 0.4 2.2 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 XP_011272651.1 - 0.015 14.5 0.1 0.027 13.6 0.1 1.4 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Chlorosome_CsmC PF11098.3 XP_011272651.1 - 0.091 12.4 0.9 0.22 11.2 0.6 1.6 1 0 0 1 1 1 0 Chlorosome envelope protein C HAD_2 PF13419.1 XP_011272652.1 - 8.4e-11 42.3 0.0 1.7e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase zf-rbx1 PF12678.2 XP_011272652.1 - 3.1e-07 30.4 0.8 6.8e-07 29.3 0.5 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 XP_011272652.1 - 6.4e-07 29.1 1.3 2.3e-06 27.3 0.9 1.9 1 1 0 1 1 1 1 Ring finger domain Hydrolase PF00702.21 XP_011272652.1 - 4.4e-06 27.2 0.0 5.6e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 XP_011272652.1 - 0.00044 19.8 0.0 0.0008 19.0 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like zf-C3HC4 PF00097.20 XP_011272652.1 - 0.00046 19.7 1.1 0.00093 18.8 0.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 XP_011272652.1 - 0.0016 18.4 2.4 0.0025 17.7 0.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 XP_011272652.1 - 0.0024 17.5 0.7 0.0049 16.5 0.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 XP_011272652.1 - 0.014 15.1 0.1 0.042 13.5 0.1 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_3 PF13920.1 XP_011272652.1 - 0.032 13.9 0.7 0.064 12.9 0.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2921 PF11145.3 XP_011272652.1 - 0.038 11.7 0.5 0.06 11.0 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2921) FANCL_C PF11793.3 XP_011272652.1 - 0.044 13.7 2.5 0.1 12.5 1.7 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain Memo PF01875.12 XP_011272652.1 - 0.052 12.4 0.0 0.23 10.2 0.0 1.9 2 0 0 2 2 2 0 Memo-like protein Hydrolase_6 PF13344.1 XP_011272652.1 - 0.068 13.0 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase zf-Apc11 PF12861.2 XP_011272652.1 - 0.11 12.4 0.2 0.24 11.2 0.1 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Grp1_Fun34_YaaH PF01184.14 XP_011272653.1 - 4.5e-67 225.4 18.0 5.7e-67 225.0 12.4 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF2721 PF11026.3 XP_011272653.1 - 0.036 13.7 0.8 0.036 13.7 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) MFS_1 PF07690.11 XP_011272654.1 - 4.4e-44 150.6 39.5 4.4e-44 150.6 27.4 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 XP_011272654.1 - 2.9e-12 45.9 15.9 2.9e-12 45.9 11.0 2.6 3 1 0 3 3 3 1 Sugar (and other) transporter DHDPS PF00701.17 XP_011272656.1 - 2.4e-33 115.0 0.0 3.2e-33 114.5 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Fungal_trans PF04082.13 XP_011272657.1 - 3.2e-24 85.2 12.3 3.9e-24 84.9 7.4 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 XP_011272657.1 - 3.2e-08 33.3 9.5 5.6e-08 32.5 6.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mito_fiss_reg PF05308.6 XP_011272657.1 - 0.0037 16.6 0.3 0.0095 15.3 0.2 1.6 1 0 0 1 1 1 1 Mitochondrial fission regulator Uds1 PF15456.1 XP_011272657.1 - 0.062 13.3 4.5 2.3 8.2 0.0 2.8 2 0 0 2 2 2 0 Up-regulated During Septation MR_MLE_C PF13378.1 XP_011272658.1 - 1e-19 70.5 0.0 2.1e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 XP_011272658.1 - 2.4e-11 43.9 0.0 6.2e-11 42.6 0.0 1.8 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 XP_011272658.1 - 1.4e-06 28.2 0.0 2.3e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain adh_short_C2 PF13561.1 XP_011272659.1 - 6e-28 98.2 0.0 7.1e-28 97.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 XP_011272659.1 - 1.7e-24 86.6 0.4 2.1e-24 86.3 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 XP_011272659.1 - 7e-08 32.3 0.2 1.1e-07 31.6 0.2 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 XP_011272659.1 - 0.036 13.8 0.5 0.085 12.6 0.4 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Amidohydro_2 PF04909.9 XP_011272660.1 - 1e-08 35.0 0.0 3.3e-08 33.4 0.0 1.7 2 0 0 2 2 2 1 Amidohydrolase His_Phos_2 PF00328.17 XP_011272661.1 - 3.5e-17 62.7 1.0 5e-17 62.2 0.7 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) HIG_1_N PF04588.8 XP_011272661.1 - 0.026 14.2 0.2 0.026 14.2 0.1 1.8 2 0 0 2 2 2 0 Hypoxia induced protein conserved region SKG6 PF08693.5 XP_011272661.1 - 0.35 10.2 0.9 0.78 9.1 0.6 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Bac_luciferase PF00296.15 XP_011272662.1 - 1.2e-54 185.5 0.0 1.6e-54 185.1 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase MFS_1 PF07690.11 XP_011272663.1 - 6.3e-34 117.2 18.6 2.8e-33 115.0 12.3 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Tetraspannin PF00335.15 XP_011272663.1 - 0.013 14.7 4.0 0.041 13.1 2.8 1.8 1 0 0 1 1 1 0 Tetraspanin family DUF2678 PF10856.3 XP_011272663.1 - 0.1 12.3 0.2 0.1 12.3 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2678) FMO-like PF00743.14 XP_011272664.1 - 9.5e-26 90.0 4.6 1.8e-11 43.0 0.0 3.4 3 1 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 XP_011272664.1 - 1.1e-18 68.0 0.0 7.9e-12 45.6 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 XP_011272664.1 - 9.6e-08 32.1 0.0 0.002 18.0 0.0 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 XP_011272664.1 - 8.7e-05 22.3 0.0 0.006 16.3 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 XP_011272664.1 - 0.00018 20.5 1.9 0.0044 16.0 0.1 3.1 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 XP_011272664.1 - 0.0018 18.2 0.0 0.0077 16.2 0.0 2.1 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 XP_011272664.1 - 0.04 12.8 0.0 4 6.2 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase Shikimate_DH PF01488.15 XP_011272664.1 - 0.054 13.5 0.7 4.2 7.4 0.0 2.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF3445 PF11927.3 XP_011272665.1 - 1e-76 257.6 0.0 1.2e-76 257.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) hSH3 PF14603.1 XP_011272665.1 - 0.092 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Helically-extended SH3 domain RCR PF12273.3 XP_011272666.1 - 3.5e-32 111.7 4.4 3.5e-32 111.7 3.0 2.1 2 0 0 2 2 2 1 Chitin synthesis regulation, resistance to Congo red DUF202 PF02656.10 XP_011272666.1 - 0.13 12.4 1.0 0.22 11.7 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF202) OSTbeta PF15048.1 XP_011272666.1 - 0.18 11.8 0.3 0.43 10.6 0.2 1.6 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein Aldedh PF00171.17 XP_011272667.1 - 9.6e-157 522.0 0.0 1.1e-156 521.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family 3H PF02829.9 XP_011272668.1 - 0.0094 15.9 0.1 0.027 14.4 0.0 1.7 2 0 0 2 2 2 1 3H domain Rad51 PF08423.6 XP_011272669.1 - 2e-27 95.7 0.0 4.4e-27 94.6 0.0 1.5 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 XP_011272669.1 - 6.7e-06 25.6 0.0 1.1e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 XP_011272669.1 - 7.6e-05 21.9 0.0 9.4e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 XP_011272669.1 - 0.0001 21.5 2.3 0.00054 19.1 1.6 2.2 1 1 0 1 1 1 1 KaiC HTH_Mga PF08280.6 XP_011272669.1 - 0.039 13.7 1.1 0.039 13.7 0.7 2.2 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain Maf1 PF09174.5 XP_011272670.1 - 8.8e-43 146.2 5.4 2.1e-42 145.0 3.7 1.6 1 1 0 1 1 1 1 Maf1 regulator DUF221 PF02714.10 XP_011272671.1 - 4.6e-107 357.6 15.5 4.6e-107 357.6 10.7 1.8 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 XP_011272671.1 - 1.9e-41 141.2 0.9 1.9e-41 141.2 0.6 2.9 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 XP_011272671.1 - 2.2e-27 94.7 0.0 1.1e-26 92.5 0.0 2.1 2 0 0 2 2 2 1 Phosphate metabolism protein DUF4463 PF14703.1 XP_011272671.1 - 9.1e-16 58.1 0.2 1.7e-15 57.2 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) ATG19_autophagy PF12744.2 XP_011272672.1 - 1.7e-10 40.6 9.8 1.7e-10 40.6 6.8 2.3 2 1 1 3 3 3 1 Autophagy protein Atg19, Atg8-binding ZZ PF00569.12 XP_011272672.1 - 2.8e-09 36.3 7.6 5.4e-09 35.4 5.3 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type ubiquitin PF00240.18 XP_011272672.1 - 0.0077 15.6 0.2 0.03 13.6 0.2 2.0 1 0 0 1 1 1 1 Ubiquitin family HMG_box PF00505.14 XP_011272673.1 - 1.3e-09 38.1 1.4 2.5e-09 37.2 1.0 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 XP_011272673.1 - 4.4e-08 33.3 0.9 9.9e-08 32.2 0.6 1.6 1 0 0 1 1 1 1 HMG-box domain DUF3987 PF13148.1 XP_011272673.1 - 0.041 12.4 3.0 0.066 11.7 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Tox-HNH-EHHH PF15657.1 XP_011272673.1 - 0.22 11.7 2.7 0.36 11.0 1.9 1.3 1 0 0 1 1 1 0 HNH/Endo VII superfamily nuclease toxins DRIM PF07539.7 XP_011272674.1 - 1.1e-34 118.8 4.0 2e-34 118.0 0.5 3.5 2 0 0 2 2 2 1 Down-regulated in metastasis HEAT PF02985.17 XP_011272674.1 - 2.8e-06 26.9 0.7 4.2 7.7 0.0 6.5 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.1 XP_011272674.1 - 0.71 10.4 1.5 1.3e+02 3.1 0.0 4.7 4 0 0 4 4 4 0 HEAT-like repeat DUF155 PF02582.9 XP_011272675.1 - 9.6e-60 201.4 1.8 3.8e-59 199.5 1.2 1.9 2 0 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 UPF0449 PF15136.1 XP_011272675.1 - 0.027 14.6 0.2 0.11 12.7 0.0 2.0 1 1 0 2 2 2 0 Uncharacterised protein family UPF0449 Histone PF00125.19 XP_011272676.1 - 1e-25 89.6 0.0 1.3e-25 89.2 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 XP_011272676.1 - 8e-06 25.8 0.0 1.1e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 XP_011272677.1 - 3e-22 78.5 0.2 4.2e-22 78.0 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 XP_011272677.1 - 1.2e-07 31.6 0.1 2.6e-07 30.5 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 XP_011272677.1 - 0.0041 17.3 0.0 0.007 16.6 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A NAD_binding_10 PF13460.1 XP_011272678.1 - 2.5e-06 27.6 0.1 3.7e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 XP_011272678.1 - 3.9e-06 26.8 0.4 1.2e-05 25.2 0.3 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 XP_011272678.1 - 0.00056 19.6 0.3 0.0029 17.2 0.4 2.1 2 1 0 2 2 2 1 KR domain NAD_binding_7 PF13241.1 XP_011272678.1 - 0.00079 19.6 0.0 0.0015 18.7 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Epimerase PF01370.16 XP_011272678.1 - 0.0013 18.2 0.1 0.002 17.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 XP_011272678.1 - 0.0049 16.6 0.0 0.0094 15.7 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DFP PF04127.10 XP_011272678.1 - 0.0087 15.7 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein NmrA PF05368.8 XP_011272678.1 - 0.013 14.7 0.2 0.022 14.0 0.1 1.4 1 0 0 1 1 1 0 NmrA-like family RmlD_sub_bind PF04321.12 XP_011272678.1 - 0.013 14.4 0.0 0.018 13.9 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain ApbA PF02558.11 XP_011272678.1 - 0.022 14.1 0.0 0.035 13.5 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3Beta_HSD PF01073.14 XP_011272678.1 - 0.033 12.8 0.1 0.051 12.2 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family zf-C3HC PF07967.8 XP_011272679.1 - 0.043 13.5 0.2 0.079 12.7 0.1 1.4 1 0 0 1 1 1 0 C3HC zinc finger-like Asp PF00026.18 XP_011272680.1 - 1.5e-60 205.0 3.9 1.9e-60 204.7 2.7 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 XP_011272680.1 - 1.2e-06 28.6 0.1 1.9e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 XP_011272680.1 - 5.9e-05 23.4 0.2 0.053 14.0 0.0 3.5 3 0 0 3 3 3 1 Aspartyl protease TAXi_C PF14541.1 XP_011272680.1 - 0.0046 16.5 0.0 0.019 14.5 0.0 2.0 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal SOR_SNZ PF01680.12 XP_011272681.1 - 9.2e-105 348.8 3.5 1.2e-104 348.4 2.5 1.1 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 XP_011272681.1 - 1.3e-10 40.7 0.7 2.6e-08 33.2 0.0 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.12 XP_011272681.1 - 0.00012 21.0 0.0 0.0053 15.6 0.0 2.2 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) NanE PF04131.9 XP_011272681.1 - 0.00023 20.1 0.3 0.026 13.5 0.0 2.4 2 1 0 2 2 2 2 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.16 XP_011272681.1 - 0.0039 16.4 0.1 0.11 11.7 0.0 2.7 3 0 0 3 3 3 1 Histidine biosynthesis protein NMO PF03060.10 XP_011272681.1 - 0.017 14.2 0.5 0.26 10.3 0.0 2.3 2 0 0 2 2 2 0 Nitronate monooxygenase IGPS PF00218.16 XP_011272681.1 - 0.027 13.5 0.1 0.14 11.2 0.0 2.0 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase FMN_dh PF01070.13 XP_011272681.1 - 0.027 13.3 0.1 0.064 12.0 0.0 1.6 2 0 0 2 2 2 0 FMN-dependent dehydrogenase Ribosomal_S5_C PF03719.10 XP_011272681.1 - 0.062 12.5 0.1 0.22 10.8 0.0 1.9 2 0 0 2 2 2 0 Ribosomal protein S5, C-terminal domain SNO PF01174.14 XP_011272682.1 - 7.5e-66 221.3 0.0 3.2e-51 173.6 0.0 2.0 1 1 1 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 XP_011272682.1 - 1.6e-12 47.2 0.0 6.7e-12 45.2 0.0 1.8 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.23 XP_011272682.1 - 7e-05 22.3 0.0 0.00033 20.1 0.0 1.9 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DUF4066 PF13278.1 XP_011272682.1 - 0.0095 15.2 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 Putative amidotransferase Peptidase_S51 PF03575.12 XP_011272682.1 - 0.011 15.5 0.0 0.023 14.4 0.0 1.5 2 0 0 2 2 2 0 Peptidase family S51 DJ-1_PfpI PF01965.19 XP_011272682.1 - 0.014 14.8 0.0 0.021 14.3 0.0 1.2 1 0 0 1 1 1 0 DJ-1/PfpI family MFS_1 PF07690.11 XP_011272683.1 - 3e-46 157.7 45.2 1e-45 155.9 31.3 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 XP_011272683.1 - 1e-10 40.8 28.3 4.5e-09 35.4 7.7 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 XP_011272683.1 - 1.3e-06 26.9 26.4 2.9e-06 25.8 18.3 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) GATA PF00320.22 XP_011272684.1 - 1e-13 50.3 2.1 2.2e-13 49.3 1.5 1.6 1 0 0 1 1 1 1 GATA zinc finger Sar8_2 PF03058.9 XP_011272684.1 - 0.086 13.1 0.9 0.2 12.0 0.6 1.5 1 0 0 1 1 1 0 Sar8.2 family Peptidase_M16 PF00675.15 XP_011272687.1 - 1.4e-22 80.1 0.0 2.7e-22 79.1 0.0 1.5 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 XP_011272687.1 - 4.9e-07 29.6 0.1 2.3e-06 27.4 0.1 1.9 2 0 0 2 2 2 1 Peptidase M16 inactive domain Borrelia_lipo_1 PF05714.6 XP_011272687.1 - 0.023 13.7 0.7 0.039 13.0 0.5 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi virulent strain associated lipoprotein HSDR_N_2 PF13588.1 XP_011272688.1 - 0.0091 15.7 1.1 0.045 13.5 0.1 2.5 2 1 0 2 2 2 1 Type I restriction enzyme R protein N terminus (HSDR_N) APH PF01636.18 XP_011272688.1 - 0.13 12.0 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Glycos_transf_2 PF00535.21 XP_011272689.1 - 8e-30 103.7 0.0 1e-29 103.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 XP_011272689.1 - 1.2e-08 35.0 0.0 1.6e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 XP_011272689.1 - 2.5e-07 30.0 0.0 3.7e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 MFS_1 PF07690.11 XP_011272690.1 - 9.3e-21 73.9 20.9 9.3e-21 73.9 14.5 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily hDGE_amylase PF14701.1 XP_011272691.1 - 9.5e-173 574.9 0.2 1.4e-172 574.3 0.1 1.3 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 XP_011272691.1 - 1.8e-120 402.0 0.1 3.5e-120 401.1 0.0 1.5 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 XP_011272691.1 - 7.2e-74 248.2 0.0 1.3e-73 247.3 0.0 1.5 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 XP_011272691.1 - 6.8e-21 73.9 0.7 2e-20 72.4 0.2 2.1 2 0 0 2 2 2 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.19 XP_011272691.1 - 1.2e-10 41.2 0.2 9.6e-07 28.4 0.1 2.5 2 0 0 2 2 2 2 Alpha amylase, catalytic domain ATP-synt_E PF05680.7 XP_011272691.1 - 0.028 14.3 0.0 0.072 13.0 0.0 1.6 1 0 0 1 1 1 0 ATP synthase E chain DUF3199 PF11436.3 XP_011272691.1 - 0.074 12.8 0.1 0.23 11.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3199) ATG13 PF10033.4 XP_011272692.1 - 4.4e-66 222.6 2.0 6.8e-66 222.0 1.4 1.3 1 0 0 1 1 1 1 Autophagy-related protein 13 WGG PF10273.4 XP_011272692.1 - 0.077 13.0 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Pre-rRNA-processing protein TSR2 zf-C2H2 PF00096.21 XP_011272693.1 - 2e-29 100.1 65.9 4e-05 23.6 1.3 9.3 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 XP_011272693.1 - 2.9e-19 67.8 60.3 0.00026 21.1 1.1 9.3 9 0 0 9 9 9 8 C2H2-type zinc finger zf-H2C2_2 PF13465.1 XP_011272693.1 - 1.1e-18 66.4 61.0 5.5e-05 23.2 0.8 10.0 9 1 1 10 10 10 6 Zinc-finger double domain zf-C2H2_jaz PF12171.3 XP_011272693.1 - 1.4e-11 44.1 30.7 0.014 15.4 0.2 8.4 9 0 0 9 9 9 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 XP_011272693.1 - 9.3e-10 38.3 26.4 0.0016 18.5 0.4 7.8 8 0 0 8 8 8 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 XP_011272693.1 - 0.2 11.6 0.2 0.2 11.6 0.1 6.5 6 0 0 6 6 6 0 C2H2-type zinc finger GCC2_GCC3 PF07699.8 XP_011272693.1 - 0.25 10.9 0.0 0.25 10.9 0.0 4.4 3 1 1 4 4 4 0 GCC2 and GCC3 RNA_pol_Rpb6 PF01192.17 XP_011272694.1 - 4.4e-25 87.1 0.2 6.6e-25 86.6 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 Pox_RNA_Pol_19 PF05320.7 XP_011272694.1 - 0.46 10.2 2.4 1.3 8.7 1.6 1.6 1 1 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit EF-hand_7 PF13499.1 XP_011272695.1 - 5.9e-05 23.1 4.3 6.1e-05 23.0 1.9 1.8 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 XP_011272695.1 - 0.00021 20.9 3.6 0.00055 19.5 0.3 3.0 3 1 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.27 XP_011272695.1 - 0.0011 18.1 2.7 0.0012 18.0 0.4 2.2 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.1 XP_011272695.1 - 0.0037 16.5 1.6 0.0096 15.2 1.1 1.8 1 0 0 1 1 1 1 EF hand FliG_N PF14842.1 XP_011272695.1 - 0.021 14.8 0.4 0.78 9.8 0.1 2.2 2 0 0 2 2 2 0 FliG N-terminal domain Hormone_recep PF00104.25 XP_011272695.1 - 0.055 12.5 0.3 0.08 12.0 0.2 1.3 1 0 0 1 1 1 0 Ligand-binding domain of nuclear hormone receptor Asp-B-Hydro_N PF05279.6 XP_011272695.1 - 0.099 12.4 1.3 0.12 12.1 0.9 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region EF-hand_8 PF13833.1 XP_011272695.1 - 0.83 9.3 5.7 0.67 9.6 0.1 2.9 3 1 1 4 4 4 0 EF-hand domain pair RNA_pol_Rpc82 PF05645.8 XP_011272696.1 - 4.8e-52 177.0 0.6 7.2e-52 176.4 0.4 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.6 XP_011272696.1 - 1.6e-20 72.7 2.3 1.6e-19 69.5 0.1 3.1 3 1 0 3 3 3 1 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.12 XP_011272696.1 - 0.00036 20.0 0.0 0.0027 17.1 0.0 2.3 2 0 0 2 2 2 1 TFIIE alpha subunit TrmB PF01978.14 XP_011272696.1 - 0.00038 20.1 0.4 0.043 13.5 0.0 2.8 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_34 PF13601.1 XP_011272696.1 - 0.023 14.7 0.1 2.4 8.2 0.0 2.6 2 0 0 2 2 2 0 Winged helix DNA-binding domain Aldo_ket_red PF00248.16 XP_011272697.1 - 3.3e-44 150.8 0.0 4e-44 150.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF2293 PF10056.4 XP_011272697.1 - 0.12 12.4 0.1 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2293) IF2_N PF04760.10 XP_011272697.1 - 0.13 11.9 0.0 2.1 8.0 0.0 2.6 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region Glyco_hydro_3 PF00933.16 XP_011272698.1 - 1.5e-88 296.6 0.0 2.5e-88 295.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 XP_011272698.1 - 2.8e-47 161.1 0.0 5.7e-47 160.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 XP_011272698.1 - 4.8e-24 84.0 0.1 1.2e-23 82.8 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain Pmp3 PF01679.12 XP_011272698.1 - 3e-14 52.4 9.3 7.4e-14 51.1 6.5 1.7 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Pmp3 PF01679.12 XP_011272699.1 - 5.3e-19 67.6 6.1 6.6e-19 67.3 4.2 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Zip PF02535.17 XP_011272699.1 - 0.0052 15.8 2.3 0.006 15.6 1.6 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Suf PF05843.9 XP_011272699.1 - 5.6 6.6 16.8 6.8 6.3 11.6 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PAT1 PF09770.4 XP_011272699.1 - 6.8 4.7 41.1 7.7 4.6 28.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CITED PF04487.7 XP_011272699.1 - 7.3 6.7 20.4 8.9 6.4 14.1 1.1 1 0 0 1 1 1 0 CITED EphA2_TM PF14575.1 XP_011272699.1 - 9.3 6.7 8.1 7.4e+02 0.6 5.6 2.4 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Lactamase_B PF00753.22 XP_011272700.1 - 2.5e-31 108.8 0.2 3.4e-31 108.4 0.2 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 XP_011272700.1 - 0.0001 21.8 0.1 0.00057 19.4 0.1 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain CNH PF00780.17 XP_011272702.1 - 2.8e-06 26.9 0.0 6.7e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 CNH domain Vps39_1 PF10366.4 XP_011272702.1 - 0.00017 21.5 0.2 0.0016 18.4 0.1 2.8 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 XRN_N PF03159.13 XP_011272704.1 - 9.3e-104 345.9 0.2 5.7e-103 343.4 0.0 2.3 3 0 0 3 3 3 1 XRN 5'-3' exonuclease N-terminus Methyltransf_28 PF02636.12 XP_011272705.1 - 1.7e-36 125.8 0.0 2.9e-36 125.1 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.11 XP_011272705.1 - 0.0043 16.0 0.1 0.01 14.7 0.0 1.6 2 0 0 2 2 2 1 PRMT5 arginine-N-methyltransferase Methyltransf_31 PF13847.1 XP_011272705.1 - 0.0071 15.9 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 XP_011272705.1 - 0.015 15.7 0.0 0.034 14.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 XP_011272705.1 - 0.083 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain FYVE PF01363.16 XP_011272706.1 - 4.2e-15 55.4 11.8 8e-15 54.5 8.2 1.5 1 0 0 1 1 1 1 FYVE zinc finger IBR PF01485.16 XP_011272706.1 - 0.023 14.5 12.2 0.07 13.0 4.9 2.4 2 0 0 2 2 2 0 IBR domain FYVE_2 PF02318.11 XP_011272706.1 - 2.4 8.1 11.5 0.6 10.0 5.2 1.9 1 1 1 2 2 2 0 FYVE-type zinc finger Sod_Fe_C PF02777.13 XP_011272707.1 - 1.2e-10 41.1 2.3 0.00029 20.6 0.1 2.5 1 1 1 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Pal1 PF08316.6 XP_011272708.1 - 1e-49 168.5 3.4 1e-49 168.5 2.4 3.2 2 2 0 3 3 3 1 Pal1 cell morphology protein MIP-T3 PF10243.4 XP_011272708.1 - 0.2 10.1 26.9 0.28 9.6 18.7 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Hex_IIIa PF02455.11 XP_011272708.1 - 8 5.0 13.8 12 4.4 9.6 1.2 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) SMN PF06003.7 XP_011272709.1 - 0.025 13.6 3.4 0.026 13.6 2.4 1.0 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) ABA_GPCR PF12430.3 XP_011272710.1 - 8.5e-33 113.1 14.6 8.5e-33 113.1 10.1 2.7 2 1 0 2 2 2 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 XP_011272710.1 - 3.1e-13 49.5 0.5 3.1e-13 49.5 0.4 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3735) Glyco_hydro_76 PF03663.9 XP_011272711.1 - 3.2e-44 151.8 0.6 4.3e-44 151.3 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Prenyltrans_2 PF13249.1 XP_011272711.1 - 0.0036 17.6 0.2 0.57 10.6 0.0 2.7 2 1 0 2 2 2 1 Prenyltransferase-like Glyco_hydro_88 PF07470.8 XP_011272711.1 - 0.004 16.2 8.2 0.27 10.2 1.7 3.0 1 1 2 3 3 3 2 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.8 XP_011272711.1 - 0.0072 15.6 0.3 0.088 12.0 0.0 2.4 2 1 0 2 2 2 1 D-glucuronyl C5-epimerase C-terminus DUF1680 PF07944.7 XP_011272711.1 - 0.0082 14.4 0.5 1.2 7.3 0.0 2.1 2 0 0 2 2 2 2 Putative glycosyl hydrolase of unknown function (DUF1680) WD40 PF00400.27 XP_011272712.1 - 7.8e-17 60.4 15.0 0.0021 17.8 0.0 8.1 8 0 0 8 8 8 5 WD domain, G-beta repeat DUF3284 PF11687.3 XP_011272712.1 - 0.00026 20.7 0.1 0.0011 18.6 0.1 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3284) Astro_capsid PF03115.9 XP_011272712.1 - 0.44 8.7 10.7 0.09 11.0 1.7 2.2 2 0 0 2 2 2 0 Astrovirus capsid protein precursor Cnd3 PF12719.2 XP_011272713.1 - 7.1e-90 301.0 6.9 8.6e-90 300.7 2.8 2.7 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 XP_011272713.1 - 3.2e-10 40.1 3.1 0.00022 21.4 0.0 4.7 2 1 3 5 5 5 3 HEAT repeats HEAT PF02985.17 XP_011272713.1 - 6.8e-07 28.8 0.2 0.31 11.2 0.0 5.5 5 0 0 5 5 5 1 HEAT repeat Sigma70_ner PF04546.8 XP_011272713.1 - 0.001 18.7 9.3 0.001 18.7 6.5 4.7 3 1 0 3 3 3 1 Sigma-70, non-essential region HEAT_EZ PF13513.1 XP_011272713.1 - 0.026 15.0 1.6 2.2 8.9 0.1 4.2 4 0 0 4 4 4 0 HEAT-like repeat Sterol_MT_C PF08498.5 XP_011272714.1 - 3.2e-29 100.6 1.2 4.7e-29 100.1 0.8 1.2 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 XP_011272714.1 - 2.9e-17 62.9 0.0 8.6e-17 61.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 XP_011272714.1 - 3.5e-16 59.1 0.0 6.6e-16 58.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 XP_011272714.1 - 9.3e-12 45.2 0.1 2.6e-11 43.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 XP_011272714.1 - 1e-11 44.4 0.3 1.4e-11 43.9 0.2 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 XP_011272714.1 - 1.3e-11 44.5 0.0 2e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 XP_011272714.1 - 4.8e-11 42.9 0.0 1.4e-10 41.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 XP_011272714.1 - 2.4e-10 40.9 0.0 6.5e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 XP_011272714.1 - 1e-07 31.9 0.0 2.9e-07 30.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 XP_011272714.1 - 2.8e-07 29.9 0.0 4.1e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 XP_011272714.1 - 0.00012 21.5 0.0 0.00022 20.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.5 XP_011272714.1 - 0.00015 21.3 0.0 0.00025 20.6 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.8 XP_011272714.1 - 0.0013 17.9 0.0 0.0054 15.8 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.13 XP_011272714.1 - 0.0098 15.1 0.0 0.021 14.0 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase PCMT PF01135.14 XP_011272714.1 - 0.058 12.9 0.0 0.093 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 XP_011272714.1 - 0.083 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain SIR2 PF02146.12 XP_011272715.1 - 8.9e-63 211.2 0.2 7.9e-62 208.1 0.0 2.4 3 0 0 3 3 3 1 Sir2 family DUF592 PF04574.8 XP_011272715.1 - 3.3e-28 98.1 4.2 2.6e-14 53.0 2.2 2.8 1 1 1 2 2 2 2 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.17 XP_011272715.1 - 0.0024 17.6 0.0 1.2 8.8 0.0 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain DUF164 PF02591.10 XP_011272715.1 - 0.12 12.2 0.5 0.37 10.6 0.4 1.9 1 1 0 1 1 1 0 Putative zinc ribbon domain BLOC1_2 PF10046.4 XP_011272715.1 - 1.2 9.2 5.5 1.8 8.7 0.0 3.0 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4239 PF14023.1 XP_011272716.1 - 2.8 7.2 3.9 18 4.6 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) His_Phos_1 PF00300.17 XP_011272717.1 - 2e-40 138.4 0.0 2.6e-40 138.0 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Pneumovirus_M2 PF06436.6 XP_011272717.1 - 0.071 12.3 0.3 0.16 11.1 0.2 1.6 1 1 0 1 1 1 0 Pneumovirus matrix protein 2 (M2) zf-C2H2_4 PF13894.1 XP_011272718.1 - 1.9e-06 27.7 2.6 0.073 13.4 0.0 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 XP_011272718.1 - 1.1e-05 25.4 7.0 0.0046 17.2 0.2 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type Histone PF00125.19 XP_011272719.1 - 2.6e-15 56.2 0.2 3.2e-15 56.0 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 XP_011272719.1 - 2.4e-05 24.3 0.1 3.3e-05 23.9 0.1 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 XP_011272719.1 - 2.6e-05 24.0 0.1 3.6e-05 23.6 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 XP_011272719.1 - 3.5e-05 23.7 0.1 5.9e-05 23.0 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 XP_011272719.1 - 0.00041 19.7 0.0 0.00044 19.6 0.0 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 XP_011272719.1 - 0.0026 17.4 0.0 0.0032 17.1 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.8 XP_011272719.1 - 0.057 13.7 0.1 0.11 12.8 0.1 1.4 1 1 0 1 1 1 0 Transcription initiation factor TFIID subunit A TFIID-31kDa PF02291.10 XP_011272719.1 - 0.12 12.1 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Cse1 PF08506.5 XP_011272720.1 - 1.7e-47 161.7 5.2 2.1e-28 98.9 0.3 2.0 1 1 1 2 2 2 2 Cse1 Phyto_Pns9_10 PF05878.6 XP_011272720.1 - 0.017 14.1 0.2 0.024 13.6 0.1 1.2 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 MFS_1 PF07690.11 XP_011272721.1 - 3.3e-25 88.5 26.6 3.3e-25 88.5 18.5 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.11 XP_011272722.1 - 3.1e-33 114.9 14.5 3.1e-27 95.2 1.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily FMN_dh PF01070.13 XP_011272723.1 - 1.6e-93 313.4 0.0 2e-58 197.9 0.0 2.0 1 1 1 2 2 2 2 FMN-dependent dehydrogenase Glu_synthase PF01645.12 XP_011272723.1 - 2.2e-07 30.1 0.0 5.2e-07 28.9 0.0 1.6 2 0 0 2 2 2 1 Conserved region in glutamate synthase IMPDH PF00478.20 XP_011272723.1 - 6.1e-05 22.0 0.1 0.00028 19.9 0.0 2.0 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 XP_011272723.1 - 0.015 14.4 0.0 0.022 13.9 0.0 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase His_biosynth PF00977.16 XP_011272723.1 - 0.055 12.7 0.8 2.3 7.4 0.1 2.3 1 1 1 2 2 2 0 Histidine biosynthesis protein ThiG PF05690.9 XP_011272723.1 - 0.1 11.6 0.0 5.7 5.9 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG MFS_1 PF07690.11 XP_011272724.1 - 1.2e-33 116.3 25.4 1.2e-33 116.3 17.6 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 XP_011272724.1 - 6.3e-10 38.2 23.6 9.5e-10 37.6 16.4 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter YfaZ PF07437.6 XP_011272724.1 - 0.017 14.5 0.0 0.69 9.3 0.0 2.2 2 0 0 2 2 2 0 YfaZ precursor Sulf_transp PF04143.9 XP_011272725.1 - 0.013 15.4 7.1 0.013 15.4 4.9 4.2 3 2 0 3 3 3 0 Sulphur transport DUF4341 PF14241.1 XP_011272725.1 - 0.025 14.2 1.1 0.025 14.2 0.8 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4341) VPS9 PF02204.13 XP_011272726.1 - 1e-25 89.7 1.5 1.9e-25 88.8 1.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Phage_Integr_2 PF13009.1 XP_011272726.1 - 0.00083 18.3 1.5 0.0011 18.0 1.1 1.2 1 0 0 1 1 1 1 Putative phage integrase C9orf72-like PF15019.1 XP_011272726.1 - 0.0067 15.6 0.1 0.011 14.9 0.1 1.4 1 0 0 1 1 1 1 C9orf72-like protein family GlutR_dimer PF00745.15 XP_011272726.1 - 0.1 12.5 0.1 0.45 10.4 0.1 2.1 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain Asn_synthase PF00733.16 XP_011272727.1 - 1.1e-45 156.1 0.0 1.6e-45 155.6 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 XP_011272727.1 - 7.2e-15 54.8 0.1 1.1e-12 47.7 0.0 3.2 1 1 1 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.1 XP_011272727.1 - 2.1e-09 37.4 0.0 1.1e-08 35.0 0.0 2.2 2 1 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.3 XP_011272727.1 - 0.0085 15.3 0.0 0.018 14.2 0.0 1.5 1 0 0 1 1 1 1 Aluminium induced protein Rad10 PF03834.9 XP_011272728.1 - 9.8e-26 89.2 3.5 1.5e-25 88.6 2.4 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) Prefoldin PF02996.12 XP_011272729.1 - 3.3e-26 91.2 3.0 4.2e-26 90.9 2.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit Occludin_ELL PF07303.8 XP_011272729.1 - 0.075 13.7 5.2 1.9 9.2 0.0 2.1 2 0 0 2 2 2 0 Occludin homology domain ASL_C2 PF14698.1 XP_011272729.1 - 0.095 12.7 0.1 0.25 11.4 0.1 1.8 1 0 0 1 1 1 0 Argininosuccinate lyase C-terminal Cdc6_C PF09079.6 XP_011272729.1 - 0.098 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 CDC6, C terminal DUF2077 PF09850.4 XP_011272729.1 - 0.26 10.6 1.8 0.41 10.0 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2077) Med2 PF11214.3 XP_011272729.1 - 0.33 11.0 6.8 2.4 8.2 0.1 2.2 2 0 0 2 2 2 0 Mediator complex subunit 2 TMCO5 PF14992.1 XP_011272729.1 - 0.72 8.9 8.2 0.068 12.3 1.8 1.8 2 0 0 2 2 2 0 TMCO5 family BLOC1_2 PF10046.4 XP_011272729.1 - 2.1 8.5 8.0 13 6.0 0.1 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 YqzH PF14164.1 XP_011272729.1 - 4.7 7.2 6.2 6.4 6.7 0.0 2.8 2 1 0 2 2 2 0 YqzH-like protein Utp14 PF04615.8 XP_011272730.1 - 1.1e-197 658.6 100.1 1.1e-197 658.6 69.4 2.0 1 1 1 2 2 2 1 Utp14 protein Proteasome PF00227.21 XP_011272731.1 - 9.2e-61 204.4 0.0 1.4e-60 203.8 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 XP_011272731.1 - 1.3e-10 40.3 0.7 2.4e-10 39.5 0.1 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature RRM_5 PF13893.1 XP_011272732.1 - 0.00067 19.4 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 XP_011272732.1 - 0.0017 17.9 0.0 0.0028 17.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.19 XP_011272732.1 - 0.02 14.5 2.3 0.046 13.4 1.6 1.7 1 1 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Rtf2 PF04641.7 XP_011272733.1 - 4.7e-36 124.3 6.0 5.9e-36 124.0 4.2 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_5 PF14634.1 XP_011272733.1 - 0.0036 16.9 3.8 0.0071 16.0 2.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-Nse PF11789.3 XP_011272733.1 - 0.0042 16.5 6.9 0.17 11.4 0.1 2.6 1 1 1 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_2 PF13639.1 XP_011272733.1 - 0.03 14.1 2.3 0.051 13.4 1.6 1.4 1 0 0 1 1 1 0 Ring finger domain DUF3571 PF12095.3 XP_011272733.1 - 0.035 14.3 0.1 0.089 13.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3571) zf-C3HC4_2 PF13923.1 XP_011272733.1 - 0.11 12.4 3.9 0.24 11.4 2.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) c-SKI_SMAD_bind PF08782.5 XP_011272733.1 - 0.11 12.5 1.2 0.24 11.5 0.8 1.5 1 1 0 1 1 1 0 c-SKI Smad4 binding domain Eapp_C PF10238.4 XP_011272733.1 - 0.15 11.9 3.0 0.24 11.3 2.1 1.3 1 0 0 1 1 1 0 E2F-associated phosphoprotein Ish1 PF10281.4 XP_011272734.1 - 4e-35 119.5 41.6 2.6e-06 27.3 1.4 8.2 8 0 0 8 8 8 7 Putative stress-responsive nuclear envelope protein HeH PF12949.2 XP_011272734.1 - 3.9e-09 35.9 5.9 0.038 13.5 0.0 5.6 6 0 0 6 6 6 3 HeH/LEM domain SAP PF02037.22 XP_011272734.1 - 0.015 14.7 0.0 9.9 5.8 0.0 4.4 4 0 0 4 4 4 0 SAP domain DUF3102 PF11300.3 XP_011272734.1 - 0.029 14.3 1.1 4.4 7.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3102) HTH_28 PF13518.1 XP_011272734.1 - 0.089 12.8 0.2 26 4.9 0.0 3.4 4 0 0 4 4 4 0 Helix-turn-helix domain UPF0149 PF03695.8 XP_011272734.1 - 0.11 12.4 1.3 0.7 9.7 0.0 2.6 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0149) Slx4 PF09494.5 XP_011272734.1 - 0.25 11.1 10.3 2.3 8.0 0.1 5.7 7 0 0 7 7 7 0 Slx4 endonuclease DUF883 PF05957.8 XP_011272734.1 - 0.46 10.9 6.3 0.37 11.2 0.6 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) GatB_Yqey PF02637.13 XP_011272734.1 - 0.5 10.0 5.0 2.4 7.8 0.1 3.7 3 1 0 3 3 3 0 GatB domain SAM_2 PF07647.12 XP_011272734.1 - 1.5 8.6 7.2 49 3.8 0.1 4.8 5 0 0 5 5 5 0 SAM domain (Sterile alpha motif) SAP30_Sin3_bdg PF13867.1 XP_011272734.1 - 2.9 7.8 5.3 21 5.0 0.0 3.4 3 0 0 3 3 3 0 Sin3 binding region of histone deacetylase complex subunit SAP30 RPM2 PF08579.6 XP_011272736.1 - 2.7e-28 98.5 6.6 2.7e-28 98.5 4.6 4.7 3 1 0 3 3 3 1 Mitochondrial ribonuclease P subunit (RPM2) PPR_2 PF13041.1 XP_011272736.1 - 0.00037 20.4 1.4 0.12 12.3 0.0 4.2 4 0 0 4 4 4 1 PPR repeat family DUF4524 PF15025.1 XP_011272736.1 - 0.024 14.0 0.9 0.055 12.9 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4524) HMG_CoA_synt_C PF08540.5 XP_011272737.1 - 1.9e-104 349.1 2.9 2.3e-104 348.8 2.0 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 XP_011272737.1 - 2.5e-66 222.4 1.7 5.9e-63 211.5 0.2 2.3 1 1 1 2 2 2 2 Hydroxymethylglutaryl-coenzyme A synthase N terminal F-box-like PF12937.2 XP_011272738.1 - 5.7e-11 41.9 0.0 1.1e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 XP_011272738.1 - 4.5e-07 29.3 0.1 1.1e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 F-box domain DUF2428 PF10350.4 XP_011272739.1 - 9.3e-62 208.3 0.2 8.4e-61 205.2 0.0 2.4 2 0 0 2 2 2 1 Putative death-receptor fusion protein (DUF2428) HEAT_2 PF13646.1 XP_011272739.1 - 1.2e-06 28.6 0.4 0.015 15.6 0.0 4.7 4 0 0 4 4 4 1 HEAT repeats HEAT PF02985.17 XP_011272739.1 - 0.00017 21.3 3.9 3.1 8.1 0.0 5.5 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 XP_011272739.1 - 0.0045 17.4 0.5 0.43 11.1 0.0 4.2 4 1 0 4 4 4 1 HEAT-like repeat Mg_trans_NIPA PF05653.9 XP_011272740.1 - 8.9e-113 376.2 15.8 1.1e-112 375.9 10.9 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 XP_011272740.1 - 8.7e-08 32.3 1.7 8.7e-08 32.3 1.2 3.3 2 1 0 2 2 2 1 Multidrug resistance efflux transporter EamA PF00892.15 XP_011272740.1 - 8.9e-05 22.5 6.2 8.9e-05 22.5 4.3 3.6 3 1 1 4 4 4 2 EamA-like transporter family CytochromB561_N PF09786.4 XP_011272740.1 - 0.00082 17.9 0.9 0.11 10.9 0.0 2.0 2 0 0 2 2 2 2 Cytochrome B561, N terminal TrbC PF04956.8 XP_011272740.1 - 0.0065 16.4 0.8 0.0065 16.4 0.5 2.9 3 1 0 3 3 3 1 TrbC/VIRB2 family Multi_Drug_Res PF00893.14 XP_011272740.1 - 0.047 14.1 1.2 0.047 14.1 0.8 2.9 4 1 0 4 4 4 0 Small Multidrug Resistance protein RseC_MucC PF04246.7 XP_011272740.1 - 0.054 13.0 1.3 3.6 7.1 0.0 2.7 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF2937 PF11157.3 XP_011272740.1 - 0.068 12.4 1.7 0.099 11.9 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) DUF4131 PF13567.1 XP_011272740.1 - 0.16 11.3 4.0 2.3 7.5 0.0 2.7 2 2 0 2 2 2 0 Domain of unknown function (DUF4131) DUF1673 PF07895.6 XP_011272740.1 - 2.8 7.4 10.8 1.4 8.4 5.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1673) eIF-1a PF01176.14 XP_011272741.1 - 2.6e-26 90.8 0.2 3.6e-26 90.3 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 CTK3 PF12243.3 XP_011272742.1 - 1.1e-35 122.3 1.5 1.9e-35 121.5 1.1 1.3 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.3 XP_011272742.1 - 3.2e-19 68.7 1.6 3.2e-19 68.7 1.1 2.2 2 1 0 2 2 2 1 CTD kinase subunit gamma CTK3 C-terminus Glyco_transf_20 PF00982.16 XP_011272743.1 - 7.9e-158 525.8 1.6 1e-157 525.4 1.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 XP_011272743.1 - 3.3e-25 88.3 0.0 2.2e-24 85.6 0.0 2.0 2 0 0 2 2 2 1 Trehalose-phosphatase TatD_DNase PF01026.16 XP_011272744.1 - 3.3e-34 118.2 0.0 4.2e-34 117.8 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Poty_PP PF08440.5 XP_011272744.1 - 0.015 14.4 0.2 0.048 12.7 0.0 1.9 2 1 0 2 2 2 0 Potyviridae polyprotein AcetylCoA_hydro PF02550.10 XP_011272745.1 - 5.2e-59 199.3 0.0 9e-59 198.5 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.1 XP_011272745.1 - 3.9e-37 127.3 0.0 6.5e-37 126.5 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain CitF PF04223.7 XP_011272745.1 - 0.0021 16.7 0.0 0.04 12.6 0.0 2.1 2 0 0 2 2 2 1 Citrate lyase, alpha subunit (CitF) CoA_trans PF01144.18 XP_011272745.1 - 0.043 12.9 0.0 0.22 10.6 0.0 2.2 3 0 0 3 3 3 0 Coenzyme A transferase AAA_2 PF07724.9 XP_011272747.1 - 2.5e-51 174.0 0.5 5.3e-49 166.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 XP_011272747.1 - 3.4e-26 90.9 0.3 3.4e-26 90.9 0.2 2.5 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 XP_011272747.1 - 9.4e-22 77.6 0.1 7.8e-11 42.3 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 XP_011272747.1 - 8.7e-17 61.1 0.2 1.1e-11 44.5 0.0 3.7 2 1 1 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 XP_011272747.1 - 2.4e-14 53.7 4.2 0.00016 21.7 0.0 4.3 3 2 2 5 5 4 3 AAA ATPase domain AAA_22 PF13401.1 XP_011272747.1 - 1.6e-09 38.0 0.0 0.00022 21.3 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_14 PF13173.1 XP_011272747.1 - 2.3e-08 34.0 0.0 0.0045 16.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 XP_011272747.1 - 4.9e-08 32.6 0.1 2.3e-05 23.9 0.0 2.7 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_18 PF13238.1 XP_011272747.1 - 8.4e-07 29.3 1.4 0.02 15.1 0.1 3.4 3 0 0 3 3 2 2 AAA domain IstB_IS21 PF01695.12 XP_011272747.1 - 5e-06 26.0 0.0 0.13 11.6 0.0 2.9 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_17 PF13207.1 XP_011272747.1 - 1.8e-05 25.5 7.9 0.056 14.2 0.0 4.3 3 1 0 4 4 3 2 AAA domain AAA_28 PF13521.1 XP_011272747.1 - 2.4e-05 24.3 0.2 0.29 11.0 0.0 3.6 4 0 0 4 4 3 2 AAA domain Arch_ATPase PF01637.13 XP_011272747.1 - 3.3e-05 23.6 15.9 0.00082 19.1 0.5 5.2 3 2 2 5 5 4 1 Archaeal ATPase MobB PF03205.9 XP_011272747.1 - 9e-05 22.2 0.0 0.22 11.2 0.0 2.9 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 XP_011272747.1 - 0.00012 21.2 0.0 0.018 14.2 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 XP_011272747.1 - 0.00013 21.1 0.0 0.0059 15.7 0.0 2.8 2 0 0 2 2 2 1 Zeta toxin NACHT PF05729.7 XP_011272747.1 - 0.00024 20.7 0.0 0.082 12.5 0.0 2.6 2 0 0 2 2 2 1 NACHT domain Mg_chelatase PF01078.16 XP_011272747.1 - 0.00029 20.0 1.2 1 8.4 0.0 3.7 3 1 0 3 3 3 2 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 XP_011272747.1 - 0.00032 21.0 5.7 0.3 11.4 0.0 4.2 3 2 0 3 3 3 1 ABC transporter RNA_helicase PF00910.17 XP_011272747.1 - 0.00034 20.7 0.2 0.61 10.2 0.0 2.9 2 1 0 2 2 2 1 RNA helicase DUF815 PF05673.8 XP_011272747.1 - 0.00064 18.7 3.8 0.17 10.8 0.2 4.0 3 2 0 3 3 2 1 Protein of unknown function (DUF815) AAA_25 PF13481.1 XP_011272747.1 - 0.00075 18.9 0.0 0.41 10.0 0.0 2.8 3 0 0 3 3 2 1 AAA domain MMR_HSR1 PF01926.18 XP_011272747.1 - 0.00079 19.3 0.2 0.048 13.6 0.0 3.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_19 PF13245.1 XP_011272747.1 - 0.0011 18.6 0.0 1.1 9.0 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain TrwB_AAD_bind PF10412.4 XP_011272747.1 - 0.0015 17.1 0.0 0.97 7.9 0.0 2.4 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain SRP54 PF00448.17 XP_011272747.1 - 0.0016 17.9 1.5 1.3 8.4 0.0 3.3 4 0 0 4 4 3 1 SRP54-type protein, GTPase domain PduV-EutP PF10662.4 XP_011272747.1 - 0.0017 17.8 0.0 0.8 9.1 0.0 2.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.1 XP_011272747.1 - 0.0028 17.1 0.1 0.13 11.8 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_30 PF13604.1 XP_011272747.1 - 0.0031 17.1 0.1 2.2 7.7 0.0 3.0 3 0 0 3 3 2 1 AAA domain UPF0079 PF02367.12 XP_011272747.1 - 0.0036 16.9 0.0 2.4 7.8 0.0 2.9 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_24 PF13479.1 XP_011272747.1 - 0.0058 16.2 0.0 2.9 7.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.6 XP_011272747.1 - 0.0063 16.1 0.0 0.14 11.7 0.0 2.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 XP_011272747.1 - 0.0074 16.7 0.0 0.16 12.4 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein T2SE PF00437.15 XP_011272747.1 - 0.0079 15.1 0.2 0.29 10.0 0.0 2.6 2 1 0 2 2 2 1 Type II/IV secretion system protein AAA_33 PF13671.1 XP_011272747.1 - 0.0082 16.0 0.2 4 7.2 0.0 2.9 3 0 0 3 3 2 0 AAA domain ATP_bind_1 PF03029.12 XP_011272747.1 - 0.027 14.0 0.0 6.6 6.1 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_10 PF12846.2 XP_011272747.1 - 0.035 13.5 0.2 0.76 9.1 0.0 3.1 2 1 1 3 3 3 0 AAA-like domain Sugarporin_N PF11471.3 XP_011272747.1 - 0.042 13.4 4.1 0.15 11.7 2.9 1.9 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Torsin PF06309.6 XP_011272747.1 - 0.046 13.6 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Torsin ResIII PF04851.10 XP_011272747.1 - 0.055 13.3 7.2 4 7.2 0.0 4.3 3 1 1 4 4 4 0 Type III restriction enzyme, res subunit PalH PF08733.5 XP_011272748.1 - 4.4e-55 186.9 22.1 7.2e-55 186.2 15.3 1.2 1 0 0 1 1 1 1 PalH/RIM21 adh_short PF00106.20 XP_011272750.1 - 8.2e-24 84.4 0.0 9.9e-24 84.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 XP_011272750.1 - 4.6e-07 29.6 0.0 6e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 XP_011272750.1 - 0.0003 20.5 0.2 0.00059 19.5 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_4 PF07993.7 XP_011272750.1 - 0.0093 14.9 0.1 0.01 14.7 0.1 1.4 1 1 0 1 1 1 1 Male sterility protein DUF1776 PF08643.5 XP_011272750.1 - 0.012 14.8 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) adh_short PF00106.20 XP_011272751.1 - 7.1e-22 78.0 0.0 8.8e-22 77.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 XP_011272751.1 - 9.3e-15 55.0 0.0 1.2e-14 54.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 XP_011272751.1 - 8.4e-05 21.8 0.0 0.00021 20.5 0.0 1.6 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.10 XP_011272751.1 - 0.00012 21.0 0.1 0.00018 20.4 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 XP_011272751.1 - 0.00034 20.3 0.0 0.00048 19.8 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 XP_011272751.1 - 0.011 15.1 0.0 0.019 14.4 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF3887 PF13026.1 XP_011272751.1 - 0.036 14.3 2.4 0.44 10.8 0.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3887) Cellulase PF00150.13 XP_011272752.1 - 1.8e-12 47.0 5.9 1.8e-12 47.0 4.1 1.9 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Colicin_D PF11429.3 XP_011272752.1 - 0.048 13.8 0.7 0.048 13.8 0.5 2.0 2 0 0 2 2 2 0 Colicin D Glyco_hydro_76 PF03663.9 XP_011272753.1 - 9.9e-146 485.8 15.7 1.2e-145 485.5 10.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 CTP_transf_2 PF01467.21 XP_011272754.1 - 8.8e-05 22.6 0.1 0.00059 19.9 0.0 2.4 1 1 0 1 1 1 1 Cytidylyltransferase DUF1374 PF07118.6 XP_011272754.1 - 0.059 13.4 1.1 72 3.5 0.1 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1374) Phos_pyr_kin PF08543.7 XP_011272755.1 - 4.4e-73 245.5 4.1 7e-73 244.8 2.8 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 XP_011272755.1 - 3.4e-44 151.1 0.1 5.7e-44 150.3 0.1 1.3 1 0 0 1 1 1 1 TENA/THI-4/PQQC family McyA_C PF12593.3 XP_011272755.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Microcystin synthetase C terminal Sec8_exocyst PF04048.9 XP_011272756.1 - 4.4e-38 130.1 0.1 4.4e-38 130.1 0.1 4.3 5 1 0 5 5 5 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 XP_011272756.1 - 6.7e-10 38.3 10.7 9.4e-10 37.8 0.4 3.5 3 1 0 3 3 3 2 Protein of unknown function N-terminal domain (DUF2450) DUF1664 PF07889.7 XP_011272756.1 - 0.0022 17.7 1.7 0.026 14.3 0.4 3.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) EPL1 PF10513.4 XP_011272757.1 - 3.1e-32 112.0 9.2 3.1e-32 112.0 6.4 3.7 3 1 0 3 3 3 1 Enhancer of polycomb-like Fumble PF03630.9 XP_011272759.1 - 3.3e-135 450.3 6.6 4.1e-135 450.0 4.6 1.1 1 0 0 1 1 1 1 Fumble ATP_transf PF09830.4 XP_011272760.1 - 2.8e-18 65.4 0.0 5.1e-18 64.6 0.0 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase HIT PF01230.18 XP_011272760.1 - 0.024 15.1 0.0 0.076 13.5 0.0 1.8 2 0 0 2 2 2 0 HIT domain UCR_14kD PF02271.11 XP_011272761.1 - 1.2e-38 131.0 0.0 1.4e-38 130.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit zf-RING_2 PF13639.1 XP_011272762.1 - 4.8e-11 42.3 3.0 8.8e-11 41.4 2.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 XP_011272762.1 - 4.1e-07 29.5 4.0 1.3e-06 27.9 2.8 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 XP_011272762.1 - 3.4e-06 26.9 4.0 7.6e-06 25.8 2.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 XP_011272762.1 - 3.3e-05 23.5 4.1 7.9e-05 22.3 2.8 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 XP_011272762.1 - 0.00012 21.6 3.4 0.00033 20.2 2.3 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 XP_011272762.1 - 0.0091 15.6 1.6 0.02 14.5 1.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.2 XP_011272762.1 - 0.02 15.0 3.9 0.073 13.1 2.7 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger PHD PF00628.24 XP_011272762.1 - 0.059 13.0 2.4 0.6 9.8 1.6 2.3 1 1 1 2 2 2 0 PHD-finger zf-C3HC4_4 PF15227.1 XP_011272762.1 - 0.43 10.4 5.2 2.5 8.0 3.6 2.3 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 XP_011272763.1 - 3e-07 30.1 7.9 5.8e-07 29.2 5.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 XP_011272763.1 - 0.0012 18.8 7.9 0.0058 16.6 5.5 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 XP_011272763.1 - 0.005 16.4 11.5 0.0087 15.7 6.7 2.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 XP_011272763.1 - 0.014 15.1 7.7 0.043 13.5 5.3 1.9 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.20 XP_011272763.1 - 0.014 15.0 7.4 0.071 12.7 5.1 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1312 PF07009.6 XP_011272763.1 - 0.022 14.5 0.0 0.064 13.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1312) PIG-X PF08320.7 XP_011272765.1 - 8.8e-42 142.7 0.9 1.4e-41 142.0 0.6 1.3 1 0 0 1 1 1 1 PIG-X / PBN1 Spb1_C PF07780.7 XP_011272766.1 - 1.6e-75 253.3 21.3 1.6e-75 253.3 14.8 3.3 3 0 0 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.14 XP_011272766.1 - 7.4e-53 179.2 0.0 1.7e-52 178.0 0.0 1.7 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.3 XP_011272766.1 - 6.1e-52 175.3 13.7 6.1e-52 175.3 9.5 4.6 4 1 1 5 5 5 1 Domain of unknown function (DUF3381) CMAS PF02353.15 XP_011272767.1 - 1.5e-61 207.8 0.2 1.8e-61 207.6 0.2 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 XP_011272767.1 - 1.2e-12 47.8 0.0 1.9e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 XP_011272767.1 - 1.1e-09 38.6 0.0 2e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 XP_011272767.1 - 1.7e-07 31.7 0.0 5.5e-07 30.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 XP_011272767.1 - 3.1e-06 27.5 0.0 5.5e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 XP_011272767.1 - 1.1e-05 25.0 0.0 1.9e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 XP_011272767.1 - 0.00045 20.5 0.0 0.0008 19.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 XP_011272767.1 - 0.00054 19.3 0.0 0.0012 18.1 0.0 1.5 1 0 0 1 1 1 1 Histone methylation protein DOT1 MTS PF05175.9 XP_011272767.1 - 0.0013 18.0 0.0 0.002 17.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 XP_011272767.1 - 0.0026 17.7 0.0 0.0061 16.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 XP_011272767.1 - 0.19 10.8 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MT-A70 PF05063.9 XP_011272768.1 - 3.7e-12 46.1 0.7 2.2e-11 43.6 0.0 2.2 2 0 0 2 2 2 1 MT-A70 CagX PF03524.10 XP_011272768.1 - 4.6 6.4 15.0 0.18 11.0 5.7 2.0 1 1 1 2 2 2 0 Conjugal transfer protein Flocculin_t3 PF13928.1 XP_011272770.1 - 2.9e-12 46.4 24.2 2.9e-12 46.4 16.8 5.0 2 1 1 3 3 3 2 Flocculin type 3 repeat QCR10 PF09796.4 XP_011272772.1 - 0.46 10.1 4.4 0.7 9.6 3.0 1.3 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) ArfGap PF01412.13 XP_011272773.1 - 2.4e-29 101.5 0.5 2.4e-29 101.5 0.4 3.1 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Pkinase PF00069.20 XP_011272774.1 - 7.5e-71 238.3 0.0 1.6e-70 237.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011272774.1 - 1.9e-47 161.5 0.0 3e-47 160.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 XP_011272774.1 - 0.0002 20.4 0.0 0.00042 19.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Recep_L_domain PF01030.19 XP_011272775.1 - 7.2e-07 29.1 9.0 0.00034 20.5 0.7 4.4 2 1 1 3 3 3 2 Receptor L domain DHHA2 PF02833.9 XP_011272776.1 - 2.4e-23 82.7 1.4 5.1e-23 81.6 1.0 1.6 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.15 XP_011272776.1 - 8.6e-07 28.7 0.2 2.6e-06 27.1 0.0 1.9 2 1 0 2 2 2 1 DHH family DUF4149 PF13664.1 XP_011272777.1 - 3.7e-14 52.6 1.8 5.1e-14 52.1 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) MAS20 PF02064.10 XP_011272778.1 - 2.9e-22 78.8 0.2 1.1e-21 77.0 0.1 1.8 1 1 0 1 1 1 1 MAS20 protein import receptor GOLD_2 PF13897.1 XP_011272778.1 - 0.029 14.6 0.1 0.063 13.5 0.1 1.6 1 1 1 2 2 2 0 Golgi-dynamics membrane-trafficking ATP-synt_E PF05680.7 XP_011272778.1 - 0.062 13.2 0.7 0.092 12.7 0.5 1.3 1 0 0 1 1 1 0 ATP synthase E chain SLX9 PF15341.1 XP_011272779.1 - 9.4e-21 74.4 15.3 9.4e-21 74.4 10.6 1.9 2 0 0 2 2 2 1 Ribosome biogenesis protein SLX9 DUF1548 PF07579.6 XP_011272779.1 - 0.13 12.3 1.3 0.7 9.9 0.1 2.1 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1548) MCPVI PF02993.9 XP_011272779.1 - 8.8 6.4 8.5 4.6 7.3 4.3 1.6 1 1 1 2 2 2 0 Minor capsid protein VI NAD_Gly3P_dh_N PF01210.18 XP_011272780.1 - 1.6e-48 164.3 0.0 2.7e-48 163.6 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 XP_011272780.1 - 1.2e-45 154.8 0.2 2e-45 154.1 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus ApbA PF02558.11 XP_011272780.1 - 0.037 13.4 0.0 0.07 12.5 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Hexapep PF00132.19 XP_011272781.1 - 4.6e-10 38.5 8.0 5.3e-09 35.1 4.0 2.5 2 0 0 2 2 2 1 Bacterial transferase hexapeptide (six repeats) Mac PF12464.3 XP_011272781.1 - 6.5e-10 38.8 0.2 1.1e-09 38.2 0.1 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep_2 PF14602.1 XP_011272781.1 - 0.00017 21.0 5.4 0.00017 21.0 3.8 2.3 2 0 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase ADH_zinc_N PF00107.21 XP_011272782.1 - 3e-31 107.6 0.8 4.7e-31 107.0 0.5 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 XP_011272782.1 - 4e-30 103.7 0.4 7.3e-30 102.9 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain CelD_N PF02927.9 XP_011272782.1 - 0.064 13.5 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 N-terminal ig-like domain of cellulase PGK PF00162.14 XP_011272783.1 - 1e-110 369.9 1.6 1.4e-80 270.7 0.1 2.0 1 1 1 2 2 2 2 Phosphoglycerate kinase DUF3353 PF11833.3 XP_011272784.1 - 0.00078 18.9 0.1 0.00086 18.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3353) Glucos_trans_II PF14264.1 XP_011272784.1 - 0.0054 15.7 0.8 0.0065 15.5 0.5 1.1 1 0 0 1 1 1 1 Glucosyl transferase GtrII DUF4293 PF14126.1 XP_011272784.1 - 0.0071 16.2 1.9 0.01 15.7 1.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4293) EpsG PF14897.1 XP_011272784.1 - 0.0091 14.9 0.3 0.01 14.7 0.2 1.1 1 0 0 1 1 1 1 EpsG family GpcrRhopsn4 PF10192.4 XP_011272784.1 - 0.014 14.5 3.1 0.028 13.6 1.0 1.8 1 1 1 2 2 2 0 Rhodopsin-like GPCR transmembrane domain DUF3397 PF11877.3 XP_011272784.1 - 0.017 15.1 0.8 0.024 14.6 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3397) YfhO PF09586.5 XP_011272784.1 - 0.041 11.9 0.2 0.043 11.8 0.2 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Cation_ATPase_C PF00689.16 XP_011272784.1 - 0.044 13.2 3.8 0.079 12.4 2.7 1.5 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus 7TM-7TMR_HD PF07698.6 XP_011272784.1 - 0.07 12.5 5.7 0.15 11.4 3.9 1.5 1 1 0 1 1 1 0 7TM receptor with intracellular HD hydrolase E1-E2_ATPase PF00122.15 XP_011272784.1 - 0.091 11.7 2.2 0.06 12.3 0.5 1.4 2 0 0 2 2 2 0 E1-E2 ATPase DUF4131 PF13567.1 XP_011272784.1 - 0.11 11.9 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF1275 PF06912.6 XP_011272784.1 - 0.15 11.2 1.8 0.2 10.8 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1275) DUF983 PF06170.7 XP_011272784.1 - 0.16 12.0 1.0 0.27 11.3 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF983) DUF912 PF06024.7 XP_011272784.1 - 0.83 9.7 3.2 0.73 9.9 0.3 2.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) 7tm_4 PF13853.1 XP_011272784.1 - 1.4 8.7 6.8 0.58 9.9 2.0 1.9 1 1 1 2 2 2 0 Olfactory receptor gpUL132 PF11359.3 XP_011272784.1 - 1.4 8.2 5.7 0.49 9.6 1.0 1.9 1 1 1 2 2 2 0 Glycoprotein UL132 DUF805 PF05656.9 XP_011272784.1 - 1.8 8.3 4.2 7.3 6.4 2.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF805) DUF843 PF05814.6 XP_011272784.1 - 2.8 7.7 7.8 0.86 9.4 2.5 2.1 1 1 1 2 2 2 0 Baculovirus protein of unknown function (DUF843) DUF3753 PF12575.3 XP_011272784.1 - 3 7.7 9.5 0.58 10.0 0.9 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3753) 2-Hacid_dh_C PF02826.14 XP_011272785.1 - 1.5e-45 154.5 0.0 2.8e-45 153.6 0.0 1.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 XP_011272785.1 - 1.6e-15 56.7 0.0 2.5e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 XP_011272785.1 - 1.4e-05 24.9 0.0 6.4e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 XP_011272785.1 - 0.0004 20.2 0.1 0.78 9.5 0.0 2.2 2 0 0 2 2 2 2 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Shikimate_DH PF01488.15 XP_011272785.1 - 0.0018 18.3 0.1 0.044 13.8 0.0 2.4 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase IlvN PF07991.7 XP_011272785.1 - 0.054 12.8 0.1 0.19 11.0 0.0 2.0 2 1 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain MTS PF05175.9 XP_011272785.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Aldo_ket_red PF00248.16 XP_011272786.1 - 4.4e-62 209.4 0.1 5e-62 209.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family rve_2 PF13333.1 XP_011272786.1 - 0.046 13.7 0.1 6 7.0 0.0 2.7 2 0 0 2 2 2 0 Integrase core domain Aldo_ket_red PF00248.16 XP_011272787.1 - 1.4e-40 138.9 0.0 1.7e-40 138.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Zn_clus PF00172.13 XP_011272788.1 - 9.8e-06 25.3 11.8 1.6e-05 24.6 8.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LRR_6 PF13516.1 XP_011272788.1 - 1.2 9.4 7.0 9.7 6.6 1.0 2.9 3 0 0 3 3 3 0 Leucine Rich repeat AIM24 PF01987.12 XP_011272790.1 - 5.4e-07 29.2 0.0 6.7e-07 28.9 0.0 1.4 1 1 0 1 1 1 1 Mitochondrial biogenesis AIM24 NuA4 PF09340.5 XP_011272791.1 - 1e-22 79.5 4.2 1e-22 79.5 2.9 1.7 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 BPL_N PF09825.4 XP_011272791.1 - 0.061 12.0 6.5 0.068 11.9 4.5 1.0 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal DUF1087 PF06465.8 XP_011272791.1 - 0.065 13.1 2.3 0.065 13.1 1.6 2.2 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1087) DUF1002 PF06207.6 XP_011272791.1 - 0.23 10.7 4.7 0.37 10.0 3.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) GLE1 PF07817.8 XP_011272791.1 - 0.33 9.8 3.0 0.35 9.7 2.1 1.1 1 0 0 1 1 1 0 GLE1-like protein DUF3847 PF12958.2 XP_011272791.1 - 1.7 8.4 6.5 2.1 8.1 2.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) Actin PF00022.14 XP_011272792.1 - 4.6e-90 301.8 0.0 5.2e-90 301.7 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 XP_011272792.1 - 0.0039 15.8 0.1 0.64 8.5 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein tRNA-synt_His PF13393.1 XP_011272793.1 - 2.7e-39 135.0 0.1 6.8e-35 120.6 0.0 2.1 2 0 0 2 2 2 2 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 XP_011272793.1 - 5.7e-18 65.0 0.0 5.2e-17 61.9 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 XP_011272793.1 - 2.8e-14 52.8 0.0 5.7e-14 51.8 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 XP_011272793.1 - 0.0038 16.0 0.0 0.082 11.6 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 XP_011272793.1 - 0.026 13.7 0.0 0.045 12.9 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) IDO PF01231.13 XP_011272794.1 - 3.3e-165 549.6 0.0 3.8e-165 549.4 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase WD40 PF00400.27 XP_011272795.1 - 0.021 14.6 0.1 4.8 7.2 0.0 3.7 3 0 0 3 3 3 0 WD domain, G-beta repeat zf-rbx1 PF12678.2 XP_011272795.1 - 0.068 13.2 7.4 0.035 14.2 2.5 2.2 1 1 1 2 2 2 0 RING-H2 zinc finger zf-RING_2 PF13639.1 XP_011272795.1 - 0.14 11.9 10.5 0.04 13.7 2.7 3.1 2 1 0 2 2 2 0 Ring finger domain HypA PF01155.14 XP_011272795.1 - 8.5 6.1 7.4 0.22 11.1 0.5 1.7 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Pkinase PF00069.20 XP_011272796.1 - 4.4e-67 225.9 0.0 1.3e-66 224.4 0.0 1.9 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011272796.1 - 3.7e-37 127.8 0.0 8.4e-37 126.6 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.11 XP_011272796.1 - 1.5e-20 72.6 17.4 4.9e-13 48.6 3.4 3.8 3 1 1 4 4 4 2 Hr1 repeat C1_1 PF00130.17 XP_011272796.1 - 1.8e-18 65.9 35.6 4.1e-11 42.4 7.8 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 XP_011272796.1 - 1.1e-11 45.0 2.2 3.2e-11 43.5 1.6 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Lgl_C PF08596.5 XP_011272797.1 - 2.3e-128 428.0 0.3 2.1e-127 424.8 0.0 2.3 2 1 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 XP_011272797.1 - 0.026 14.4 0.1 8.5 6.4 0.0 3.9 3 0 0 3 3 3 0 WD domain, G-beta repeat IKI3 PF04762.7 XP_011272797.1 - 0.35 8.6 0.0 0.58 7.9 0.0 1.2 1 0 0 1 1 1 0 IKI3 family TPR_11 PF13414.1 XP_011272798.1 - 6.8e-22 76.8 7.1 2.2e-14 52.8 1.0 2.6 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 XP_011272798.1 - 1.8e-13 49.4 2.8 4.6e-07 29.1 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 XP_011272798.1 - 1.9e-10 39.8 2.3 0.00028 20.5 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 XP_011272798.1 - 9.4e-09 34.7 1.3 0.0029 17.6 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 XP_011272798.1 - 3.5e-08 33.9 4.6 6.9e-06 26.5 0.6 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 XP_011272798.1 - 8.5e-08 31.4 2.3 0.003 17.2 0.1 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 XP_011272798.1 - 1.9e-05 24.8 0.9 0.00011 22.4 0.2 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 XP_011272798.1 - 0.00012 21.9 3.5 0.0018 18.1 0.3 2.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 XP_011272798.1 - 0.0011 18.7 0.1 0.0023 17.7 0.1 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.1 XP_011272798.1 - 0.0016 18.6 2.4 0.091 13.1 0.0 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_20 PF14561.1 XP_011272798.1 - 0.08 13.0 0.2 0.19 11.8 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Cid2 PF09774.4 XP_011272799.1 - 6.1e-29 101.0 1.7 7.3e-29 100.8 1.2 1.0 1 0 0 1 1 1 1 Caffeine-induced death protein 2 DicB PF05358.6 XP_011272799.1 - 0.034 13.6 0.1 0.099 12.1 0.0 1.7 2 0 0 2 2 2 0 DicB protein zf-HC5HC2H_2 PF13832.1 XP_011272800.1 - 7.8e-35 119.2 6.8 7.8e-35 119.2 4.7 2.6 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 XP_011272800.1 - 1.1e-29 102.3 5.3 1.1e-29 102.3 3.7 3.6 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.1 XP_011272800.1 - 6.2e-14 51.0 8.0 6.7e-14 50.9 1.3 2.7 2 0 0 2 2 2 1 PHD-finger PHD PF00628.24 XP_011272800.1 - 1.8e-08 33.9 8.9 1.8e-08 33.9 6.2 3.5 4 0 0 4 4 4 2 PHD-finger EPL1 PF10513.4 XP_011272800.1 - 1.2e-06 28.8 11.5 1.7e-06 28.3 4.0 2.7 2 1 0 2 2 2 1 Enhancer of polycomb-like Bromodomain PF00439.20 XP_011272800.1 - 0.0015 18.4 0.9 0.0055 16.6 0.0 2.4 3 0 0 3 3 3 1 Bromodomain C1_1 PF00130.17 XP_011272800.1 - 0.012 15.3 1.6 0.012 15.3 1.1 3.4 4 0 0 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING-like PF08746.6 XP_011272800.1 - 2.1 8.4 25.6 0.14 12.1 3.3 3.5 3 1 0 3 3 3 0 RING-like domain HLH PF00010.21 XP_011272801.1 - 1.4e-12 47.0 0.3 3.4e-12 45.8 0.1 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF2347 PF09804.4 XP_011272801.1 - 0.033 13.4 3.5 0.026 13.7 0.8 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) DUF2758 PF10957.3 XP_011272801.1 - 0.23 11.2 2.0 1.5 8.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2758) Got1 PF04178.7 XP_011272802.1 - 8.5e-33 112.9 18.1 1.1e-32 112.5 12.5 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family DUF1657 PF07870.6 XP_011272802.1 - 0.16 11.6 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1657) Imp-YgjV PF10688.4 XP_011272802.1 - 0.39 10.1 11.9 1.2 8.5 8.2 1.7 1 1 0 1 1 1 0 Bacterial inner membrane protein CoA_binding_3 PF13727.1 XP_011272802.1 - 0.79 9.5 3.8 0.71 9.6 2.0 1.3 1 1 0 1 1 1 0 CoA-binding domain DUF805 PF05656.9 XP_011272802.1 - 6.8 6.5 11.3 11 5.8 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF805) AAA PF00004.24 XP_011272803.1 - 1e-97 323.4 0.3 6.1e-48 162.3 0.0 3.1 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 XP_011272803.1 - 1.4e-19 69.7 1.4 4.9e-19 68.0 1.0 2.0 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.9 XP_011272803.1 - 4.1e-14 52.8 0.0 1.4e-07 31.6 0.0 3.1 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 XP_011272803.1 - 3.2e-13 49.2 0.0 1.7e-05 23.9 0.0 3.1 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 XP_011272803.1 - 1.9e-12 47.0 0.7 4e-06 26.6 0.0 4.0 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 XP_011272803.1 - 8.2e-12 45.1 0.0 9.5e-06 25.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 XP_011272803.1 - 1.6e-10 41.2 2.4 0.0012 18.9 0.1 4.4 3 2 1 4 4 3 2 AAA domain AAA_16 PF13191.1 XP_011272803.1 - 1.7e-10 41.1 0.0 0.0018 18.2 0.0 3.6 2 1 1 3 3 3 2 AAA ATPase domain CDC48_2 PF02933.12 XP_011272803.1 - 2.3e-10 39.9 0.0 6.6e-10 38.4 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_17 PF13207.1 XP_011272803.1 - 2.4e-10 41.2 0.0 0.00068 20.4 0.0 3.3 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 XP_011272803.1 - 2.2e-09 36.5 0.1 0.0013 17.5 0.0 2.4 2 0 0 2 2 2 2 TIP49 C-terminus AAA_14 PF13173.1 XP_011272803.1 - 2.2e-08 34.0 0.0 0.0031 17.3 0.0 3.1 3 0 0 3 3 3 2 AAA domain IstB_IS21 PF01695.12 XP_011272803.1 - 3.6e-08 33.0 0.1 0.0047 16.3 0.0 3.0 3 0 0 3 3 2 2 IstB-like ATP binding protein RNA_helicase PF00910.17 XP_011272803.1 - 9.4e-08 32.1 0.0 0.005 16.9 0.0 3.0 2 0 0 2 2 2 2 RNA helicase Zeta_toxin PF06414.7 XP_011272803.1 - 2.6e-07 29.9 0.4 0.0069 15.5 0.0 3.0 3 0 0 3 3 3 2 Zeta toxin Mg_chelatase PF01078.16 XP_011272803.1 - 2.8e-07 29.8 0.5 0.025 13.7 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 XP_011272803.1 - 6.2e-07 29.0 0.9 0.03 14.0 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain AAA_25 PF13481.1 XP_011272803.1 - 9.2e-07 28.4 9.0 0.092 12.1 0.1 4.6 2 2 2 4 4 4 2 AAA domain AAA_28 PF13521.1 XP_011272803.1 - 3.2e-06 27.2 0.4 0.11 12.4 0.0 3.0 3 0 0 3 3 2 2 AAA domain Vps4_C PF09336.5 XP_011272803.1 - 4.7e-06 26.4 0.0 5.8e-05 22.8 0.0 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_18 PF13238.1 XP_011272803.1 - 6.3e-06 26.5 0.0 0.14 12.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain ResIII PF04851.10 XP_011272803.1 - 1.2e-05 25.2 0.4 0.0051 16.6 0.0 2.9 3 0 0 3 3 2 1 Type III restriction enzyme, res subunit PhoH PF02562.11 XP_011272803.1 - 1.6e-05 24.2 0.5 0.065 12.4 0.0 2.6 2 0 0 2 2 2 2 PhoH-like protein KaiC PF06745.8 XP_011272803.1 - 2.4e-05 23.5 4.5 0.71 8.9 0.1 3.9 2 2 2 4 4 4 2 KaiC ABC_tran PF00005.22 XP_011272803.1 - 2.4e-05 24.6 0.1 0.11 12.7 0.0 3.8 3 1 0 3 3 2 1 ABC transporter Sigma54_activat PF00158.21 XP_011272803.1 - 2.8e-05 23.6 0.2 0.21 11.0 0.0 3.5 2 2 0 2 2 2 2 Sigma-54 interaction domain AAA_24 PF13479.1 XP_011272803.1 - 4.1e-05 23.2 0.1 0.23 11.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.1 XP_011272803.1 - 4.5e-05 23.1 0.0 0.33 10.4 0.0 2.8 2 1 0 2 2 2 2 AAA domain Sigma54_activ_2 PF14532.1 XP_011272803.1 - 5.8e-05 23.1 0.0 0.43 10.6 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain DUF815 PF05673.8 XP_011272803.1 - 8.3e-05 21.6 0.0 0.1 11.4 0.0 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Parvo_NS1 PF01057.12 XP_011272803.1 - 0.00014 20.7 0.1 0.47 9.2 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_3 PF07726.6 XP_011272803.1 - 0.00019 21.0 0.0 0.79 9.3 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 XP_011272803.1 - 0.00036 20.2 1.2 0.59 9.7 0.1 4.0 3 2 1 4 4 3 1 Archaeal ATPase Bac_DnaA PF00308.13 XP_011272803.1 - 0.0004 20.0 0.2 0.38 10.3 0.0 3.3 4 0 0 4 4 3 1 Bacterial dnaA protein DUF2075 PF09848.4 XP_011272803.1 - 0.00054 19.0 0.0 0.95 8.3 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) NACHT PF05729.7 XP_011272803.1 - 0.00075 19.1 0.3 3.1 7.4 0.0 3.6 3 1 0 3 3 3 0 NACHT domain AAA_30 PF13604.1 XP_011272803.1 - 0.0021 17.6 0.2 2.2 7.8 0.0 2.8 2 1 0 2 2 2 1 AAA domain KAP_NTPase PF07693.9 XP_011272803.1 - 0.011 14.7 0.0 1.7 7.5 0.0 2.7 2 1 1 3 3 3 0 KAP family P-loop domain NTPase_1 PF03266.10 XP_011272803.1 - 0.012 15.2 1.4 3.4 7.3 0.0 4.0 4 0 0 4 4 3 0 NTPase IPT PF01745.11 XP_011272803.1 - 0.012 14.7 0.1 1.9 7.6 0.0 2.4 2 0 0 2 2 2 0 Isopentenyl transferase NB-ARC PF00931.17 XP_011272803.1 - 0.015 14.1 0.2 6 5.6 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain T2SE PF00437.15 XP_011272803.1 - 0.021 13.7 0.0 2.9 6.7 0.0 2.6 2 0 0 2 2 2 0 Type II/IV secretion system protein SKI PF01202.17 XP_011272803.1 - 0.027 14.3 0.1 3.3 7.5 0.0 2.9 2 0 0 2 2 2 0 Shikimate kinase eIF-1a PF01176.14 XP_011272803.1 - 0.037 13.4 0.6 1.5 8.3 0.1 2.8 1 1 1 2 2 2 0 Translation initiation factor 1A / IF-1 UFD1 PF03152.9 XP_011272803.1 - 0.044 12.9 0.0 0.88 8.6 0.0 2.3 1 1 1 2 2 2 0 Ubiquitin fusion degradation protein UFD1 UPF0079 PF02367.12 XP_011272803.1 - 0.067 12.8 0.2 7.6 6.1 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_10 PF12846.2 XP_011272803.1 - 0.075 12.4 1.1 11 5.3 0.1 3.5 4 0 0 4 4 4 0 AAA-like domain Zot PF05707.7 XP_011272803.1 - 0.086 12.2 0.2 6.1 6.2 0.0 3.4 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) KTI12 PF08433.5 XP_011272803.1 - 0.095 11.8 0.0 5.8 6.0 0.0 2.5 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Cyclin_N PF00134.18 XP_011272804.1 - 6e-17 61.3 0.0 1.2e-16 60.4 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 XP_011272804.1 - 4.6e-14 53.0 0.0 1.2e-13 51.7 0.0 1.7 1 0 0 1 1 1 1 Cyclin Na_Ca_ex PF01699.19 XP_011272805.1 - 6.7e-49 165.1 34.9 3.7e-25 88.1 6.2 2.5 3 0 0 3 3 3 2 Sodium/calcium exchanger protein DUF3169 PF11368.3 XP_011272805.1 - 0.0039 16.4 0.7 0.0039 16.4 0.5 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF3169) Consortin_C PF15281.1 XP_011272805.1 - 0.12 11.9 0.1 0.33 10.4 0.1 1.8 1 0 0 1 1 1 0 Consortin C-terminus ATP-synt_8 PF00895.15 XP_011272805.1 - 1.3 9.3 3.5 1.7 8.9 0.0 3.0 3 0 0 3 3 3 0 ATP synthase protein 8 DUF1352 PF07086.7 XP_011272805.1 - 1.3 8.5 8.9 1.4 8.5 0.3 3.0 2 2 1 3 3 3 0 Protein of unknown function (DUF1352) DUF4271 PF14093.1 XP_011272805.1 - 8.6 5.9 16.5 0.067 12.8 3.2 3.1 1 1 1 3 3 3 0 Domain of unknown function (DUF4271) CBF PF03914.12 XP_011272806.1 - 0.047 13.1 0.1 0.076 12.4 0.0 1.4 1 0 0 1 1 1 0 CBF/Mak21 family IPK PF03770.11 XP_011272807.1 - 1.8e-48 164.7 0.1 3.4e-48 163.8 0.0 1.5 1 0 0 1 1 1 1 Inositol polyphosphate kinase DUF1848 PF08902.6 XP_011272807.1 - 0.06 12.8 0.4 0.13 11.7 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) BCAS2 PF05700.6 XP_011272809.1 - 3.4e-25 88.8 7.6 9e-25 87.4 5.2 1.6 1 1 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) ENTH PF01417.15 XP_011272810.1 - 0.068 13.0 0.8 16 5.4 0.0 3.0 2 1 0 2 2 2 0 ENTH domain IF-2B PF01008.12 XP_011272811.1 - 5.6e-87 291.3 1.0 1e-86 290.4 0.7 1.5 1 0 0 1 1 1 1 Initiation factor 2 subunit family SAGA-Tad1 PF12767.2 XP_011272811.1 - 0.26 10.9 22.3 0.1 12.2 10.5 2.3 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit B56 PF01603.15 XP_011272812.1 - 6.9e-151 502.4 13.4 6.9e-151 502.4 9.3 2.0 2 1 0 2 2 2 1 Protein phosphatase 2A regulatory B subunit (B56 family) DUF605 PF04652.11 XP_011272812.1 - 0.061 12.7 54.6 0.084 12.2 37.8 1.2 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 XP_011272812.1 - 3.3 5.8 49.4 4.7 5.3 34.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 KAR9 PF08580.5 XP_011272812.1 - 4.5 5.4 45.5 6.4 4.9 31.5 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Pil1 PF13805.1 XP_011272813.1 - 5.6e-154 511.0 0.1 6.7e-154 510.8 0.1 1.0 1 0 0 1 1 1 1 Eisosome component PIL1 Saw1 PF11561.3 XP_011272814.1 - 2.2e-15 56.6 18.8 1e-14 54.4 13.0 1.8 1 1 0 1 1 1 1 Single strand annealing-weakened 1 X PF00739.14 XP_011272814.1 - 0.088 12.7 0.1 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Trans-activation protein X Hph PF13694.1 XP_011272815.1 - 0.0064 16.5 3.8 0.015 15.3 2.6 1.6 1 1 0 1 1 1 1 Sec63/Sec62 complex-interacting family Adaptin_binding PF10199.4 XP_011272815.1 - 0.046 14.0 0.0 0.1 12.8 0.0 1.7 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 DUF1664 PF07889.7 XP_011272815.1 - 0.23 11.2 4.3 0.47 10.2 3.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Sec8_exocyst PF04048.9 XP_011272815.1 - 0.24 11.0 7.6 0.66 9.6 5.0 1.9 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain Sin3_corepress PF08295.7 XP_011272815.1 - 4.1 7.2 8.0 2.9 7.6 1.2 3.1 1 1 0 3 3 3 0 Sin3 family co-repressor Thioredoxin_4 PF13462.1 XP_011272816.1 - 1.1e-10 41.8 0.0 1.5e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.15 XP_011272816.1 - 0.16 11.5 0.2 2.1 7.8 0.0 2.1 2 0 0 2 2 2 0 DSBA-like thioredoxin domain Pkinase PF00069.20 XP_011272817.1 - 6.6e-20 71.3 0.1 1e-19 70.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011272817.1 - 2.2e-10 40.0 0.0 3.9e-10 39.2 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Ribosomal_L5_C PF00673.16 XP_011272818.1 - 2.5e-23 81.5 0.0 3.7e-23 81.0 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 XP_011272818.1 - 1.1e-19 69.8 0.2 3.1e-19 68.4 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L5 Med31 PF05669.7 XP_011272819.1 - 3.9e-39 132.5 5.1 3.9e-39 132.5 3.6 1.4 2 0 0 2 2 2 1 SOH1 CDC27 PF09507.5 XP_011272819.1 - 0.0093 15.2 5.5 0.011 14.9 3.8 1.0 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 DBR1 PF05011.8 XP_011272819.1 - 0.23 11.3 4.3 0.35 10.7 3.0 1.2 1 0 0 1 1 1 0 Lariat debranching enzyme, C-terminal domain Mis12 PF05859.7 XP_011272820.1 - 1.6e-40 138.2 1.3 3.6e-40 137.0 0.9 1.6 1 0 0 1 1 1 1 Mis12 protein zf-PHD-like PF15446.1 XP_011272820.1 - 0.037 13.3 0.0 0.064 12.5 0.0 1.3 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain GatB_N PF02934.10 XP_011272821.1 - 1.1e-100 336.2 0.0 1.4e-100 335.9 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 XP_011272821.1 - 2.2e-27 95.6 2.7 3.9e-27 94.7 1.9 1.4 1 0 0 1 1 1 1 GatB domain CRM1_C PF08767.6 XP_011272821.1 - 0.00068 18.6 0.4 0.0017 17.3 0.3 1.6 1 0 0 1 1 1 1 CRM1 C terminal GAT PF03127.9 XP_011272821.1 - 0.075 13.0 0.4 2 8.4 0.0 2.9 2 1 1 3 3 3 0 GAT domain SHS2_Rpb7-N PF03876.12 XP_011272822.1 - 4.6e-12 45.8 0.0 7.9e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Pkinase PF00069.20 XP_011272823.1 - 1.5e-42 145.5 0.1 1.5e-42 145.5 0.1 2.2 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011272823.1 - 9.3e-26 90.4 0.0 1.5e-25 89.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 XP_011272823.1 - 0.018 14.0 0.0 0.091 11.7 0.0 2.0 1 1 0 1 1 1 0 Kinase-like Ras PF00071.17 XP_011272824.1 - 1.1e-47 161.4 0.3 1.3e-47 161.1 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 XP_011272824.1 - 1.8e-15 57.5 0.2 3.4e-15 56.5 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 XP_011272824.1 - 7.8e-13 48.0 0.7 9.9e-13 47.6 0.5 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 XP_011272824.1 - 1.8e-05 24.2 0.1 2.4e-05 23.8 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 XP_011272824.1 - 0.0005 19.2 0.4 0.0011 18.1 0.3 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Bacillus_HBL PF05791.6 XP_011272824.1 - 0.017 14.4 0.3 0.024 14.0 0.2 1.3 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) YTH PF04146.10 XP_011272824.1 - 0.033 13.7 0.9 0.053 13.1 0.6 1.4 1 1 0 1 1 1 0 YT521-B-like domain Omega_Repress PF07764.6 XP_011272824.1 - 0.082 13.2 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 Omega Transcriptional Repressor Lactococcin PF04369.8 XP_011272824.1 - 0.11 12.4 0.1 0.74 9.7 0.0 2.2 2 0 0 2 2 2 0 Lactococcin-like family UPF0183 PF03676.9 XP_011272825.1 - 8.3e-41 139.8 10.9 3.9e-39 134.3 7.6 2.7 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0183) FimP PF09766.4 XP_011272826.1 - 0.018 14.0 5.5 0.019 14.0 3.8 1.0 1 0 0 1 1 1 0 Fms-interacting protein DUF912 PF06024.7 XP_011272826.1 - 0.047 13.7 3.1 0.055 13.5 2.1 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Folliculin PF11704.3 XP_011272826.1 - 0.18 11.4 2.4 0.19 11.2 1.6 1.0 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Tim54 PF11711.3 XP_011272826.1 - 0.19 10.2 2.6 0.19 10.2 1.8 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 YqfQ PF14181.1 XP_011272826.1 - 0.31 11.0 7.7 0.33 10.9 5.4 1.1 1 0 0 1 1 1 0 YqfQ-like protein Sec62 PF03839.11 XP_011272826.1 - 0.41 10.0 4.0 0.43 9.9 2.8 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Inp1 PF12634.2 XP_011272826.1 - 0.55 9.8 4.4 0.8 9.3 3.0 1.3 1 1 0 1 1 1 0 Inheritance of peroxisomes protein 1 DUF3464 PF11947.3 XP_011272826.1 - 0.82 9.1 2.9 0.88 9.0 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) Ndc1_Nup PF09531.5 XP_011272826.1 - 0.97 7.7 3.3 0.97 7.7 2.3 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DDHD PF02862.12 XP_011272826.1 - 1.1 9.0 5.6 1.1 9.0 3.8 1.1 1 0 0 1 1 1 0 DDHD domain TLP-20 PF06088.6 XP_011272826.1 - 1.2 8.8 9.1 1.4 8.5 6.3 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) DUF4407 PF14362.1 XP_011272826.1 - 1.9 7.3 7.1 2.3 7.0 4.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4175 PF13779.1 XP_011272826.1 - 2.2 5.8 8.2 2.2 5.9 5.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) CDC45 PF02724.9 XP_011272826.1 - 3.1 5.7 7.4 3.5 5.5 5.1 1.0 1 0 0 1 1 1 0 CDC45-like protein Peptidase_S49_N PF08496.5 XP_011272826.1 - 3.4 7.4 8.6 4.2 7.1 6.0 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Ribosomal_L37 PF08561.5 XP_011272826.1 - 9.1 5.9 9.3 13 5.4 6.4 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L37 CBFD_NFYB_HMF PF00808.18 XP_011272827.1 - 2.3e-19 69.2 0.8 3.3e-19 68.6 0.5 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 XP_011272827.1 - 8.2e-13 48.2 0.1 1.3e-12 47.6 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.5 XP_011272827.1 - 0.014 15.1 0.1 0.032 14.0 0.1 1.6 1 0 0 1 1 1 0 CENP-S associating Centromere protein X PAT1 PF09770.4 XP_011272827.1 - 5.6 5.0 38.8 0.85 7.7 6.9 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 PBP PF01161.15 XP_011272828.1 - 1.2e-28 99.8 0.2 1.4e-28 99.5 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DUF3453 PF11935.3 XP_011272829.1 - 2.6e-49 167.7 9.8 5.8e-49 166.6 6.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) DUF2040 PF09745.4 XP_011272830.1 - 2.1e-24 85.7 18.3 2.1e-24 85.7 12.7 3.1 2 1 1 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) BolA PF01722.13 XP_011272832.1 - 4.1e-18 65.0 0.0 1.4e-17 63.4 0.0 1.7 1 1 1 2 2 2 2 BolA-like protein RNase_T PF00929.19 XP_011272833.1 - 0.00024 21.4 0.0 0.00037 20.8 0.0 1.2 1 0 0 1 1 1 1 Exonuclease eIF2A PF08662.6 XP_011272834.1 - 5.9e-32 110.9 0.0 6.1e-29 101.1 0.0 3.9 3 2 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.17 XP_011272834.1 - 1.6e-10 40.4 0.0 3.8e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 XP_011272834.1 - 4.3e-08 33.0 0.0 1.5e-07 31.2 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 XP_011272834.1 - 8e-08 32.0 0.0 1.9e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 XP_011272834.1 - 0.026 14.4 0.7 35 4.4 0.0 5.1 6 0 0 6 6 6 0 WD domain, G-beta repeat Mto2_bdg PF12808.2 XP_011272835.1 - 0.0018 18.3 19.4 0.0018 18.3 13.5 4.9 3 1 0 3 3 3 2 Micro-tubular organiser Mto1 C-term Mto2-binding region Proteasome PF00227.21 XP_011272836.1 - 7.8e-53 178.5 0.4 9.5e-53 178.3 0.0 1.3 2 0 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.4 XP_011272836.1 - 9.5e-12 44.0 1.2 1e-11 43.9 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Con-6 PF10346.4 XP_011272836.1 - 1.7 8.1 5.6 12 5.4 1.2 2.3 2 0 0 2 2 2 0 Conidiation protein 6 Miro PF08477.8 XP_011272837.1 - 5e-36 123.7 0.0 8.9e-19 68.1 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein EF_assoc_2 PF08356.7 XP_011272837.1 - 2.9e-32 110.2 0.0 1.6e-31 107.8 0.0 2.3 3 0 0 3 3 1 1 EF hand associated EF_assoc_1 PF08355.7 XP_011272837.1 - 3.6e-32 109.4 1.4 7.3e-32 108.4 1.0 1.5 1 0 0 1 1 1 1 EF hand associated Ras PF00071.17 XP_011272837.1 - 1.1e-22 80.1 0.0 1.7e-11 43.7 0.0 2.3 2 0 0 2 2 2 2 Ras family EF-hand_1 PF00036.27 XP_011272837.1 - 4.4e-10 38.1 3.7 0.0004 19.4 0.3 2.8 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 XP_011272837.1 - 4.4e-09 36.3 0.5 0.0012 18.9 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 XP_011272837.1 - 5.1e-09 35.2 4.1 0.00036 20.1 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain MMR_HSR1 PF01926.18 XP_011272837.1 - 2.1e-07 30.9 0.0 0.013 15.4 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.18 XP_011272837.1 - 2.7e-06 27.3 0.1 0.00089 19.1 0.0 2.5 2 0 0 2 2 2 1 Dynamin family EF-hand_5 PF13202.1 XP_011272837.1 - 2.1e-05 23.6 7.1 0.011 14.9 1.5 2.6 2 0 0 2 2 2 2 EF hand AAA_16 PF13191.1 XP_011272837.1 - 2.3e-05 24.4 0.0 0.013 15.4 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 XP_011272837.1 - 0.00015 21.2 0.1 0.011 15.3 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain EF-hand_8 PF13833.1 XP_011272837.1 - 0.00045 19.7 4.3 0.14 11.8 0.6 2.6 2 0 0 2 2 2 2 EF-hand domain pair DUF258 PF03193.11 XP_011272837.1 - 0.00046 19.4 0.1 0.13 11.4 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 XP_011272837.1 - 0.0021 18.3 0.2 0.046 14.0 0.0 2.4 2 0 0 2 2 2 1 ABC transporter GTP_EFTU PF00009.22 XP_011272837.1 - 0.0026 17.2 0.0 2 7.8 0.0 2.9 4 0 0 4 4 3 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 XP_011272837.1 - 0.013 15.6 0.0 0.16 12.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.1 XP_011272837.1 - 0.026 14.4 1.6 0.18 11.7 0.0 2.6 2 1 0 2 2 2 0 AAA domain DUF815 PF05673.8 XP_011272837.1 - 0.03 13.2 0.0 1.1 8.1 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF815) AAA_33 PF13671.1 XP_011272837.1 - 0.065 13.1 0.0 0.57 10.0 0.0 2.5 3 1 0 3 3 2 0 AAA domain cobW PF02492.14 XP_011272837.1 - 0.069 12.5 0.0 1.7 8.0 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.2 XP_011272837.1 - 0.082 12.3 0.0 0.27 10.6 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain SMC_N PF02463.14 XP_011272837.1 - 0.082 12.1 0.0 0.18 11.0 0.0 1.5 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain RNA_helicase PF00910.17 XP_011272837.1 - 0.097 12.8 0.0 7.5 6.7 0.0 2.9 3 0 0 3 3 3 0 RNA helicase EF-hand_4 PF12763.2 XP_011272837.1 - 0.11 12.2 0.2 0.53 10.0 0.0 2.2 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand AAA_18 PF13238.1 XP_011272837.1 - 0.11 12.7 0.0 2.4 8.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_32 PF13654.1 XP_011272837.1 - 0.25 9.9 0.0 0.39 9.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain EF-hand_10 PF14788.1 XP_011272837.1 - 0.61 9.7 2.5 1.6 8.4 0.2 2.3 2 0 0 2 2 2 0 EF hand Abi PF02517.11 XP_011272838.1 - 1.1e-12 47.8 5.2 1.1e-12 47.8 3.6 2.3 3 1 0 3 3 3 1 CAAX protease self-immunity Zds_C PF08632.5 XP_011272839.1 - 1.5e-31 107.5 3.3 2.9e-31 106.6 2.3 1.5 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term MOFRL PF05161.8 XP_011272839.1 - 0.048 13.7 0.3 0.17 11.9 0.2 2.0 1 0 0 1 1 1 0 MOFRL family Cyt-b5 PF00173.23 XP_011272840.1 - 1.9e-18 65.9 0.5 6.6e-18 64.2 0.1 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 XP_011272840.1 - 6.8e-09 36.1 22.8 8.5e-09 35.8 13.2 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.8 XP_011272840.1 - 0.08 12.9 0.2 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region DUF1700 PF08006.6 XP_011272840.1 - 2.7 7.2 8.4 1.2 8.4 0.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1700) zf-C3HC PF07967.8 XP_011272841.1 - 3.1e-21 75.5 0.5 9.2e-19 67.5 0.0 2.7 2 1 1 3 3 3 2 C3HC zinc finger-like Rsm1 PF08600.5 XP_011272841.1 - 4.3e-05 23.2 7.8 0.18 11.6 1.4 3.9 2 2 0 2 2 2 2 Rsm1-like zinc_ribbon_5 PF13719.1 XP_011272841.1 - 0.038 13.5 0.4 2.4 7.8 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 XP_011272841.1 - 0.045 13.4 0.5 2.8 7.6 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Pribosyltran PF00156.22 XP_011272842.1 - 1.1e-17 63.8 0.5 2.5e-17 62.7 0.2 1.6 2 0 0 2 2 2 1 Phosphoribosyl transferase domain SRP19 PF01922.12 XP_011272843.1 - 4e-30 104.2 0.1 8.3e-30 103.2 0.1 1.5 1 0 0 1 1 1 1 SRP19 protein RRN9 PF10680.4 XP_011272844.1 - 3.1e-07 30.0 5.5 3.1e-07 30.0 3.8 2.8 3 1 0 3 3 3 1 RNA polymerase I specific transcription initiation factor SAPS PF04499.10 XP_011272844.1 - 0.21 10.1 14.9 0.14 10.7 4.0 2.1 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein PXA PF02194.10 XP_011272845.1 - 3.3e-40 137.6 1.0 9.8e-40 136.0 0.7 1.8 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.7 XP_011272845.1 - 1.7e-27 95.7 0.1 5.5e-27 94.0 0.1 2.0 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.19 XP_011272845.1 - 1.9e-15 56.6 6.8 3e-15 56.0 0.2 3.6 3 0 0 3 3 3 1 PX domain RGS PF00615.14 XP_011272845.1 - 1.4e-10 41.2 2.2 1.4e-10 41.2 1.5 3.8 4 0 0 4 4 4 2 Regulator of G protein signaling domain G-patch PF01585.18 XP_011272846.1 - 3.3e-05 23.5 2.1 0.00011 21.9 1.5 1.9 1 0 0 1 1 1 1 G-patch domain AAA_21 PF13304.1 XP_011272846.1 - 5.7 6.8 15.0 8.6 6.2 10.4 1.2 1 0 0 1 1 1 0 AAA domain RRM_1 PF00076.17 XP_011272847.1 - 1e-43 146.8 0.6 3.6e-13 48.9 0.1 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 XP_011272847.1 - 2.7e-35 120.1 0.1 1.8e-11 43.8 0.0 5.0 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 XP_011272847.1 - 1.5e-21 75.9 0.0 8.1e-07 28.8 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 XP_011272847.1 - 1.2e-06 28.1 0.0 0.034 13.9 0.0 3.2 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Lsm_interact PF05391.6 XP_011272847.1 - 0.00091 18.5 0.4 0.00091 18.5 0.3 3.0 2 0 0 2 2 2 1 Lsm interaction motif Nup188 PF10487.4 XP_011272848.1 - 1.4e-162 542.8 26.5 3.2e-162 541.6 18.3 1.6 1 1 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 Pyrophosphatase PF00719.14 XP_011272849.1 - 3.1e-48 163.1 0.1 4.1e-48 162.7 0.1 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase DUF221 PF02714.10 XP_011272850.1 - 3.7e-110 367.8 26.5 3.7e-110 367.8 18.4 2.1 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 XP_011272850.1 - 6.3e-43 146.0 1.2 6.3e-43 146.0 0.9 3.2 3 1 1 5 5 5 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 XP_011272850.1 - 1.8e-26 91.8 0.3 4.1e-26 90.7 0.0 1.8 2 0 0 2 2 2 1 Phosphate metabolism protein RRM_6 PF14259.1 XP_011272850.1 - 0.079 12.9 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF2636 PF11120.3 XP_011272850.1 - 0.12 11.9 2.1 1.6 8.2 0.6 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2636) Nucleoside_tran PF01733.13 XP_011272852.1 - 2e-53 181.5 27.1 1.2e-41 142.9 4.6 2.6 2 1 1 3 3 3 2 Nucleoside transporter Peptidase_C48 PF02902.14 XP_011272853.1 - 1.5e-30 106.4 9.8 3.7e-30 105.1 6.8 1.7 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Fe-S_biosyn PF01521.15 XP_011272854.1 - 5.9e-17 61.6 0.1 8.8e-17 61.0 0.1 1.3 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis PIG-L PF02585.12 XP_011272856.1 - 6.3e-19 68.7 0.0 1.1e-18 68.0 0.0 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase ATP13 PF12921.2 XP_011272857.1 - 8.9e-27 92.9 2.3 8.9e-27 92.9 1.6 2.6 3 0 0 3 3 3 2 Mitochondrial ATPase expression Init_tRNA_PT PF04179.7 XP_011272858.1 - 3.4e-129 431.6 2.4 4e-129 431.4 1.6 1.0 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase LAGLIDADG_1 PF00961.14 XP_011272858.1 - 2.3 8.8 6.8 2.8 8.5 0.6 3.3 2 1 1 3 3 3 0 LAGLIDADG endonuclease Globin PF00042.17 XP_011272859.1 - 4.2e-11 43.1 0.0 8.5e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Globin FAD_binding_6 PF00970.19 XP_011272859.1 - 5.3e-10 39.3 0.0 1.1e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 XP_011272859.1 - 1.7e-05 25.3 0.0 6.6e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain PDEase_I PF00233.14 XP_011272860.1 - 2.7e-41 141.8 7.2 1e-37 130.1 0.1 3.8 4 0 0 4 4 4 2 3'5'-cyclic nucleotide phosphodiesterase Asp PF00026.18 XP_011272861.1 - 1.8e-58 198.3 3.5 2.5e-58 197.8 2.4 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 XP_011272861.1 - 1.1e-05 25.3 0.0 0.00062 19.7 0.0 3.2 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 XP_011272861.1 - 0.00013 22.3 0.3 1 9.8 0.1 3.9 4 0 0 4 4 4 2 Aspartyl protease TAXi_C PF14541.1 XP_011272861.1 - 0.0044 16.5 0.0 0.048 13.1 0.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal SAM_2 PF07647.12 XP_011272862.1 - 3.9e-08 33.0 0.0 8e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 XP_011272862.1 - 8.8e-06 25.8 0.0 2.2e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DNA_pol_A PF00476.15 XP_011272863.1 - 5.8e-90 301.6 0.2 3.3e-88 295.9 0.0 2.7 3 1 0 3 3 3 1 DNA polymerase family A DNA_pol_A_exo1 PF01612.15 XP_011272863.1 - 0.0085 15.5 0.1 0.034 13.6 0.1 1.8 1 1 0 1 1 1 1 3'-5' exonuclease vATP-synt_E PF01991.13 XP_011272865.1 - 9.3e-51 171.9 17.1 1.1e-50 171.6 11.9 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF4061 PF13270.1 XP_011272865.1 - 0.012 15.6 1.2 0.018 15.1 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4061) Gmad2 PF10648.4 XP_011272865.1 - 0.13 12.4 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Immunoglobulin-like domain of bacterial spore germination THOC7 PF05615.8 XP_011272865.1 - 1.1 9.5 11.2 0.55 10.5 2.1 2.5 1 1 0 2 2 2 0 Tho complex subunit 7 VIT1 PF01988.14 XP_011272865.1 - 3 7.2 5.6 0.81 9.1 1.9 1.4 2 0 0 2 2 2 0 VIT family FlgN PF05130.7 XP_011272865.1 - 5 7.3 10.8 1.7 8.8 1.1 2.4 2 1 1 3 3 3 0 FlgN protein CorA PF01544.13 XP_011272866.1 - 4e-06 26.0 0.8 4e-06 26.0 0.6 2.1 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein ParG PF09274.5 XP_011272868.1 - 0.0009 19.1 1.6 1.3 8.9 0.1 3.0 2 0 0 2 2 2 2 ParG Ykof PF07615.6 XP_011272869.1 - 0.035 14.2 0.0 0.13 12.3 0.0 2.0 2 0 0 2 2 2 0 YKOF-related Family Borrelia_lipo_2 PF06238.6 XP_011272869.1 - 0.038 14.0 0.7 0.19 11.8 0.0 2.5 2 1 1 3 3 3 0 Borrelia burgdorferi BBR25 lipoprotein AMP-binding PF00501.23 XP_011272870.1 - 2.5e-74 250.1 0.0 3.1e-74 249.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 XP_011272870.1 - 1.1e-14 55.1 0.0 2e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.8 XP_011272870.1 - 0.013 14.0 0.1 0.029 12.9 0.0 1.5 2 0 0 2 2 2 0 GH3 auxin-responsive promoter Transket_pyr PF02779.19 XP_011272871.1 - 1.4e-43 148.4 0.0 2.7e-43 147.5 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 XP_011272871.1 - 7.4e-35 119.5 0.2 2e-34 118.2 0.1 1.8 1 0 0 1 1 1 1 Transketolase, C-terminal domain Acatn PF13000.2 XP_011272872.1 - 3.9e-157 524.0 35.5 4e-104 349.1 13.2 4.4 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 Scs3p PF10261.4 XP_011272873.1 - 1.6e-56 191.0 23.6 2.6e-56 190.3 16.4 1.3 1 1 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM PAP2 PF01569.16 XP_011272873.1 - 0.75 9.4 8.8 1.7 8.3 6.1 1.7 1 1 0 1 1 1 0 PAP2 superfamily Papilloma_E5A PF05776.7 XP_011272873.1 - 4 7.6 7.5 0.42 10.7 1.5 2.0 2 0 0 2 2 2 0 Papillomavirus E5A protein RasGEF_N PF00618.15 XP_011272875.1 - 0.035 14.1 0.1 0.07 13.2 0.1 1.5 1 0 0 1 1 1 0 RasGEF N-terminal motif MFS_1 PF07690.11 XP_011272876.1 - 2.6e-22 79.0 71.9 1.4e-16 60.2 30.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 XP_011272876.1 - 3.8e-05 22.2 20.7 3.8e-05 22.2 14.3 2.2 1 1 1 2 2 2 1 MFS/sugar transport protein Sec3_C_2 PF15278.1 XP_011272876.1 - 0.018 15.1 0.2 0.048 13.7 0.2 1.7 1 0 0 1 1 1 0 Sec3 exocyst complex subunit Sugar_tr PF00083.19 XP_011272876.1 - 8 4.9 45.1 0.23 10.0 11.6 3.0 1 1 1 2 2 2 0 Sugar (and other) transporter MFS_1 PF07690.11 XP_011272877.1 - 7.8e-26 90.6 64.9 1.5e-19 69.9 25.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 XP_011272877.1 - 4.6e-05 22.0 15.4 4.6e-05 22.0 10.7 2.2 1 1 1 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.19 XP_011272877.1 - 0.44 9.0 39.2 0.025 13.1 5.4 2.9 1 1 1 2 2 2 0 Sugar (and other) transporter MFS_1 PF07690.11 XP_011272878.1 - 9.3e-21 73.9 39.2 6.4e-12 44.8 14.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 XP_011272878.1 - 6.5e-05 21.5 15.9 6.5e-05 21.5 11.0 2.3 1 1 1 2 2 2 2 MFS/sugar transport protein Glyco_transf_20 PF00982.16 XP_011272879.1 - 2.2e-201 669.4 0.0 2.5e-201 669.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glycos_transf_1 PF00534.15 XP_011272879.1 - 0.0005 19.5 1.9 0.92 8.9 0.0 3.3 3 1 0 3 3 3 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 XP_011272879.1 - 0.023 14.1 0.1 0.044 13.2 0.1 1.4 1 0 0 1 1 1 0 Starch synthase catalytic domain Tau95 PF09734.4 XP_011272880.1 - 3.5e-53 180.9 9.2 4.7e-53 180.5 6.4 1.2 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit CDC45 PF02724.9 XP_011272880.1 - 0.072 11.1 3.9 0.1 10.6 2.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.8 XP_011272880.1 - 0.12 11.9 8.0 0.3 10.6 4.6 2.0 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF2457 PF10446.4 XP_011272880.1 - 0.15 10.8 18.6 0.17 10.5 12.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) CENP-B_dimeris PF09026.5 XP_011272880.1 - 1.7 8.9 16.2 3 8.1 11.2 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Daxx PF03344.10 XP_011272880.1 - 4.4 5.6 13.3 6.5 5.1 9.2 1.1 1 0 0 1 1 1 0 Daxx Family Ribosomal_L31 PF01197.13 XP_011272881.1 - 0.00042 20.2 0.0 0.001 19.0 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L31 tRNA-synt_2b PF00587.20 XP_011272882.1 - 1.6e-68 229.6 0.0 4.6e-68 228.1 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 XP_011272882.1 - 1.3e-22 79.5 1.5 5.6e-22 77.5 0.1 2.7 2 1 1 3 3 3 1 Anticodon binding domain RRM_1 PF00076.17 XP_011272884.1 - 1.8e-25 88.3 1.7 1.2e-12 47.2 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 XP_011272884.1 - 1.8e-21 75.9 0.2 5.6e-12 45.4 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 XP_011272884.1 - 1.4e-13 50.5 0.2 1.1e-09 38.0 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 XP_011272884.1 - 1.3e-05 24.8 0.8 3.1e-05 23.6 0.1 1.9 2 0 0 2 2 2 1 Limkain b1 RRM_3 PF08777.6 XP_011272884.1 - 0.042 13.6 6.7 4.5 7.1 0.0 2.8 2 1 0 2 2 2 0 RNA binding motif DUF262 PF03235.9 XP_011272884.1 - 0.43 10.5 5.5 0.61 10.0 3.8 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF262 MAAL_C PF07476.6 XP_011272885.1 - 0.0056 15.6 2.7 0.013 14.3 0.2 2.7 2 1 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus Xan_ur_permease PF00860.15 XP_011272886.1 - 3.6e-64 216.6 25.6 4.4e-64 216.3 17.1 1.5 2 0 0 2 2 2 1 Permease family FUSC_2 PF13515.1 XP_011272886.1 - 0.0065 16.3 2.9 0.0065 16.3 2.0 3.5 4 1 0 4 4 4 1 Fusaric acid resistance protein-like DUF3419 PF11899.3 XP_011272887.1 - 4.4e-142 473.2 0.0 6.2e-142 472.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_31 PF13847.1 XP_011272887.1 - 2.2e-11 43.5 0.1 2.9e-10 39.9 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.13 XP_011272887.1 - 1.8e-10 40.3 0.0 5.2e-10 38.8 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 XP_011272887.1 - 8.9e-09 35.7 0.1 4e-08 33.6 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.7 XP_011272887.1 - 3.7e-08 33.7 0.0 1.2e-07 32.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 XP_011272887.1 - 1.7e-07 31.1 0.0 2.6e-06 27.2 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 XP_011272887.1 - 1.5e-06 28.7 0.0 9.3e-05 22.9 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 XP_011272887.1 - 2.6e-06 27.4 0.0 0.00022 21.2 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain PCMT PF01135.14 XP_011272887.1 - 0.0039 16.7 0.0 0.0079 15.7 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_28 PF02636.12 XP_011272887.1 - 0.082 12.2 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DEAD PF00270.24 XP_011272888.1 - 1.3e-45 154.8 0.0 9.5e-45 152.1 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 XP_011272888.1 - 1.8e-28 98.1 0.0 5.9e-28 96.5 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 XP_011272888.1 - 0.0001 22.1 1.4 0.0022 17.8 0.0 3.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Brix PF04427.13 XP_011272889.1 - 1.3e-56 191.2 1.5 1.9e-56 190.7 1.0 1.2 1 0 0 1 1 1 1 Brix domain CAF-1_p150 PF11600.3 XP_011272889.1 - 0.63 9.3 32.8 1.2 8.5 22.7 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal NARP1 PF12569.3 XP_011272889.1 - 3.1 6.4 16.7 5.7 5.5 11.6 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Nop25 PF09805.4 XP_011272889.1 - 4.9 7.2 29.4 1.3 9.0 17.3 2.1 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) FYVE PF01363.16 XP_011272890.1 - 1.3e-20 73.0 5.4 1.3e-20 73.0 3.8 2.9 3 1 0 3 3 2 1 FYVE zinc finger zf-RING_2 PF13639.1 XP_011272890.1 - 2e-10 40.3 2.2 2e-10 40.3 1.5 4.1 2 1 1 3 3 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 XP_011272890.1 - 7.2e-05 22.7 24.4 0.0004 20.3 2.8 4.4 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 XP_011272890.1 - 0.00051 20.0 3.2 0.00051 20.0 2.2 4.0 4 1 0 4 4 4 2 RING-H2 zinc finger zf-C3HC4 PF00097.20 XP_011272890.1 - 0.0007 19.1 1.7 0.0007 19.1 1.2 4.6 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.9 XP_011272890.1 - 0.0051 16.2 3.7 0.65 9.5 0.5 2.7 2 0 0 2 2 2 2 Rad50 zinc hook motif RINGv PF12906.2 XP_011272890.1 - 0.014 15.4 2.1 0.014 15.4 1.4 3.7 4 1 1 5 5 4 0 RING-variant domain zf-RING_UBOX PF13445.1 XP_011272890.1 - 0.02 14.5 2.4 0.02 14.5 1.7 3.3 3 0 0 3 3 3 0 RING-type zinc-finger DUF581 PF04570.9 XP_011272890.1 - 0.099 11.9 4.1 9.1 5.6 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF581) zf-RING_5 PF14634.1 XP_011272890.1 - 0.2 11.3 26.7 0.11 12.2 1.7 4.3 3 1 0 3 3 3 0 zinc-RING finger domain zf-C3HC4_3 PF13920.1 XP_011272890.1 - 0.97 9.1 28.9 0.17 11.5 1.1 4.2 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DUF4428 PF14471.1 XP_011272890.1 - 1.5 8.6 15.7 0.14 11.9 1.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4428) FYVE_2 PF02318.11 XP_011272890.1 - 4.3 7.2 20.0 0.12 12.3 5.5 3.4 3 1 1 4 4 4 0 FYVE-type zinc finger FANCL_C PF11793.3 XP_011272890.1 - 5.7 6.9 15.1 0.12 12.3 1.1 3.8 4 0 0 4 4 4 0 FANCL C-terminal domain Mut7-C PF01927.11 XP_011272890.1 - 7.8 6.4 9.4 0.19 11.7 0.9 2.4 1 1 1 2 2 2 0 Mut7-C RNAse domain UBA PF00627.26 XP_011272891.1 - 3.6e-08 33.0 0.1 1.1e-07 31.4 0.0 1.9 2 0 0 2 2 2 1 UBA/TS-N domain TPR_11 PF13414.1 XP_011272891.1 - 1.3e-07 31.1 0.0 7.4e-07 28.7 0.0 2.2 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 XP_011272891.1 - 6.2e-05 22.6 0.1 0.01 15.6 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat DnaJ PF00226.26 XP_011272891.1 - 0.00014 21.4 0.0 0.00069 19.3 0.0 2.2 1 0 0 1 1 1 1 DnaJ domain TPR_1 PF00515.23 XP_011272891.1 - 0.0004 19.8 0.0 0.015 14.9 0.0 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 XP_011272891.1 - 0.0028 17.5 0.1 0.013 15.4 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat BSD PF03909.12 XP_011272892.1 - 1.6e-26 91.8 1.8 4.5e-14 51.9 0.0 3.0 2 0 0 2 2 2 2 BSD domain TFIIH_BTF_p62_N PF08567.6 XP_011272892.1 - 5.5e-20 70.8 0.1 1.2e-19 69.7 0.1 1.6 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain Acetyltransf_11 PF13720.1 XP_011272892.1 - 0.031 14.5 0.1 0.19 11.9 0.0 2.5 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 HSP70 PF00012.15 XP_011272893.1 - 1e-80 271.4 9.2 9e-79 264.9 4.8 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 XP_011272893.1 - 4.1e-12 45.3 0.8 6e-12 44.8 0.6 1.2 1 0 0 1 1 1 1 MreB/Mbl protein Hydantoinase_A PF01968.13 XP_011272893.1 - 6.6e-05 22.1 0.8 0.0022 17.1 0.2 2.2 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase ApbA PF02558.11 XP_011272894.1 - 9.3e-32 109.5 0.1 5.8e-31 106.9 0.0 2.1 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 XP_011272894.1 - 5.2e-30 104.0 0.9 7.3e-30 103.5 0.2 1.5 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal Shikimate_DH PF01488.15 XP_011272894.1 - 0.0064 16.5 0.1 0.017 15.2 0.0 1.8 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.18 XP_011272894.1 - 0.0083 15.8 0.5 0.033 13.9 0.0 2.2 3 0 0 3 3 3 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TfuA PF07812.7 XP_011272894.1 - 0.031 13.7 0.4 0.087 12.2 0.0 1.9 2 0 0 2 2 2 0 TfuA-like protein GCM PF03615.10 XP_011272894.1 - 0.12 11.9 0.1 0.71 9.4 0.0 2.0 2 0 0 2 2 2 0 GCM motif protein DUF3414 PF11894.3 XP_011272895.1 - 0 1322.9 70.6 0 1316.3 49.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3414) Nsp1_C PF05064.8 XP_011272896.1 - 5.3e-38 129.2 4.8 5.3e-38 129.2 3.3 2.1 2 1 1 3 3 3 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.1 XP_011272896.1 - 8.1e-16 58.2 100.8 2.2e-05 24.6 19.2 4.6 1 1 3 4 4 4 4 Nucleoporin FG repeat region V-SNARE PF05008.10 XP_011272896.1 - 0.0099 16.0 0.4 0.04 14.0 0.3 2.1 1 0 0 1 1 1 1 Vesicle transport v-SNARE protein N-terminus CinA PF02464.12 XP_011272896.1 - 0.062 12.7 0.6 15 4.9 0.0 3.0 1 1 1 2 2 2 0 Competence-damaged protein SHIPPO-rpt PF07004.7 XP_011272896.1 - 0.21 12.5 41.9 42 5.2 1.9 11.8 5 3 2 7 7 7 0 Sperm-tail PG-rich repeat Laminin_II PF06009.7 XP_011272896.1 - 1.4 8.6 7.9 1.9 8.2 1.5 2.4 2 1 0 2 2 2 0 Laminin Domain II GATase PF00117.23 XP_011272897.1 - 4.8e-14 52.2 0.0 6.4e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 XP_011272897.1 - 2.3e-06 27.2 0.0 3.6e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 GATase_3 PF07685.9 XP_011272897.1 - 0.014 14.9 0.0 0.026 14.1 0.0 1.6 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain EcsC PF12787.2 XP_011272897.1 - 0.045 13.1 0.0 0.83 8.9 0.0 2.1 2 0 0 2 2 2 0 EcsC protein family LRR_4 PF12799.2 XP_011272898.1 - 3.2e-07 29.8 28.2 0.0028 17.2 4.2 5.8 3 1 2 5 5 5 5 Leucine Rich repeats (2 copies) RabGAP-TBC PF00566.13 XP_011272899.1 - 6.3e-26 91.1 9.1 6.3e-26 91.1 6.3 1.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain CTP_transf_2 PF01467.21 XP_011272900.1 - 2.6e-35 121.7 0.0 4e-35 121.1 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase Apc15p PF05841.6 XP_011272900.1 - 1.7 9.4 7.5 2.8 8.6 5.2 1.3 1 0 0 1 1 1 0 Apc15p protein SSP160 PF06933.6 XP_011272901.1 - 0.32 8.9 11.5 0.29 9.0 8.0 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 His_Phos_1 PF00300.17 XP_011272902.1 - 7.7e-44 149.5 0.0 9.6e-44 149.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Calcipressin PF04847.7 XP_011272903.1 - 9.2e-21 74.2 1.9 1.3e-20 73.8 1.3 1.2 1 0 0 1 1 1 1 Calcipressin Phasin_2 PF09361.5 XP_011272903.1 - 0.03 14.3 0.7 0.15 12.0 0.1 2.0 2 0 0 2 2 2 0 Phasin protein DAP3 PF10236.4 XP_011272903.1 - 0.094 11.6 1.8 1.3 7.9 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 HTH_psq PF05225.11 XP_011272904.1 - 7.6e-06 25.3 0.2 1.5e-05 24.4 0.1 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 XP_011272904.1 - 0.0014 18.4 1.6 0.0018 18.0 0.0 2.1 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_28 PF13518.1 XP_011272904.1 - 0.0096 15.9 1.2 0.012 15.6 0.1 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_11 PF08279.7 XP_011272904.1 - 0.077 12.6 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 HTH domain Ribosomal_L1 PF00687.16 XP_011272905.1 - 7.5e-35 120.2 11.6 7.5e-35 120.2 8.0 3.2 3 1 0 4 4 4 1 Ribosomal protein L1p/L10e family DUF3646 PF12362.3 XP_011272905.1 - 0.071 13.0 0.7 16 5.4 0.1 2.5 2 0 0 2 2 2 0 DNA polymerase III gamma and tau subunits C terminal Elf1 PF05129.8 XP_011272906.1 - 5.3e-12 45.2 0.2 7.5e-12 44.7 0.1 1.3 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Gcd10p PF04189.8 XP_011272906.1 - 0.0068 15.5 1.1 0.0078 15.3 0.8 1.0 1 0 0 1 1 1 1 Gcd10p family COX5A PF02284.11 XP_011272907.1 - 9.6e-47 157.4 1.5 1.4e-46 156.9 1.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va DHC_N1 PF08385.7 XP_011272907.1 - 0.03 12.7 1.3 0.3 9.4 0.0 2.0 1 1 1 2 2 2 0 Dynein heavy chain, N-terminal region 1 HHH_8 PF14716.1 XP_011272907.1 - 0.53 10.5 2.3 0.43 10.8 0.4 1.8 2 0 0 2 2 2 0 Helix-hairpin-helix domain DUF3541 PF12060.3 XP_011272908.1 - 0.061 12.6 0.0 0.065 12.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3541) SIS PF01380.17 XP_011272910.1 - 8e-59 196.9 0.3 3.4e-31 107.5 0.1 2.4 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 XP_011272910.1 - 3.6e-31 108.1 0.1 1.6e-21 76.4 0.0 2.2 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 XP_011272910.1 - 9.2e-19 67.7 0.0 2.3e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 XP_011272910.1 - 4.9e-13 48.9 0.0 1.2e-12 47.6 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_4 PF13230.1 XP_011272910.1 - 1.6e-09 36.8 0.2 2.7e-09 36.1 0.1 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II RVT_2 PF07727.9 XP_011272911.1 - 7.2e-19 67.7 0.9 7.2e-19 67.7 0.6 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 XP_011272911.1 - 1.7e-07 31.3 0.1 4.3e-07 30.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain DUF155 PF02582.9 XP_011272913.1 - 3.9e-48 163.6 2.1 3.9e-48 163.6 1.4 1.7 2 0 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 HAD_2 PF13419.1 XP_011272914.1 - 7.8e-13 49.0 0.0 9.3e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 XP_011272914.1 - 2.5e-06 27.0 0.0 7.5e-06 25.5 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 XP_011272914.1 - 3.5e-05 24.3 0.0 0.00075 19.9 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 XP_011272914.1 - 0.00024 21.3 0.0 0.00031 20.9 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 XP_011272915.1 - 3.9e-10 40.2 0.0 4.7e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 XP_011272915.1 - 7.2e-05 22.4 0.1 0.00015 21.3 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 XP_011272915.1 - 0.0043 17.4 0.0 0.065 13.6 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 XP_011272915.1 - 0.0073 16.4 0.0 0.0095 16.1 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Peptidase_M18 PF02127.10 XP_011272916.1 - 8.7e-128 426.4 0.0 1.1e-127 426.1 0.0 1.1 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M20 PF01546.23 XP_011272916.1 - 0.00049 19.6 0.0 0.0014 18.1 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 Dsh_C PF12316.3 XP_011272916.1 - 0.044 13.8 2.5 0.076 13.1 1.7 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal DUF126 PF01989.11 XP_011272916.1 - 0.072 12.7 0.1 6.1 6.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF126 ORC6 PF05460.8 XP_011272916.1 - 0.33 10.0 6.0 0.52 9.3 4.2 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) FAM176 PF14851.1 XP_011272916.1 - 0.98 9.0 3.8 1.8 8.2 2.6 1.3 1 0 0 1 1 1 0 FAM176 family PBP1_TM PF14812.1 XP_011272916.1 - 1.2 9.4 5.7 2.4 8.5 3.9 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DS PF01916.12 XP_011272917.1 - 4.4e-145 482.4 0.0 5.2e-145 482.1 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase NDUFA12 PF05071.11 XP_011272918.1 - 9.1e-24 83.9 4.5 1.2e-23 83.5 3.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Peptidase_M1 PF01433.15 XP_011272919.1 - 1e-130 436.3 2.3 1e-130 436.3 1.6 2.1 2 0 0 2 2 2 1 Peptidase family M1 ERAP1_C PF11838.3 XP_011272919.1 - 4.9e-63 213.3 0.2 7.6e-63 212.7 0.1 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 XP_011272919.1 - 8.5e-20 71.0 0.1 1.9e-19 69.9 0.1 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily Corona_S1 PF01600.11 XP_011272919.1 - 0.0088 14.3 0.1 0.015 13.5 0.1 1.3 1 0 0 1 1 1 1 Coronavirus S1 glycoprotein DUF1522 PF07482.6 XP_011272919.1 - 0.15 12.2 3.0 3 8.0 0.0 2.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1522) Prenyltrans PF00432.16 XP_011272920.1 - 2.5e-29 100.4 3.3 2.9e-10 39.5 0.1 4.4 4 0 0 4 4 4 3 Prenyltransferase and squalene oxidase repeat Prenyltrans_1 PF13243.1 XP_011272920.1 - 1.2e-25 89.6 0.0 2.1e-16 59.8 0.1 5.4 3 3 2 5 5 5 4 Prenyltransferase-like Prenyltrans_2 PF13249.1 XP_011272920.1 - 1.5e-22 80.0 0.0 3.8e-13 49.8 0.1 4.5 2 1 2 4 4 4 4 Prenyltransferase-like Pec_lyase PF09492.5 XP_011272920.1 - 1.3e-06 27.8 0.1 0.72 8.9 0.0 4.6 4 1 1 5 5 5 3 Pectic acid lyase A2M_comp PF07678.9 XP_011272920.1 - 4.1e-05 22.9 0.4 0.072 12.3 0.0 3.6 2 1 1 4 4 4 2 A-macroglobulin complement component Glyco_transf_8C PF08437.5 XP_011272921.1 - 0.13 12.3 0.8 19 5.3 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 8 C-terminal DUF4595 PF15283.1 XP_011272921.1 - 0.17 11.5 3.7 0.31 10.6 1.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4595) with porin-like fold Methyltransf_23 PF13489.1 XP_011272922.1 - 8.4e-17 61.3 0.0 1.4e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 XP_011272922.1 - 5.7e-12 45.9 0.0 2.1e-11 44.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 XP_011272922.1 - 9.5e-11 42.0 0.0 1.4e-08 35.0 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 XP_011272922.1 - 2.8e-10 39.9 0.3 9.3e-10 38.2 0.2 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 XP_011272922.1 - 2.7e-09 36.4 0.1 0.0015 17.6 0.0 2.6 1 1 1 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 XP_011272922.1 - 1.2e-07 32.2 0.0 3.4e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 XP_011272922.1 - 3.4e-06 27.3 0.0 9.5e-06 25.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Big_3_3 PF13750.1 XP_011272922.1 - 0.016 14.6 0.1 0.032 13.6 0.1 1.4 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) ECR1_N PF14382.1 XP_011272923.1 - 5.9e-12 44.6 0.3 2.2e-11 42.8 0.1 2.2 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 XP_011272923.1 - 0.00034 20.5 0.0 0.0087 16.0 0.0 2.7 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 Met_10 PF02475.11 XP_011272924.1 - 2.7e-69 232.7 0.1 3.6e-69 232.3 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein SPOB_ab PF14682.1 XP_011272924.1 - 0.039 13.7 0.0 2.1 8.1 0.0 2.5 2 0 0 2 2 2 0 Sporulation initiation phospho-transferase B, C-terminal TRM PF02005.11 XP_011272924.1 - 0.079 11.8 0.0 0.14 11.0 0.0 1.5 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_26 PF13659.1 XP_011272924.1 - 0.089 12.8 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 XP_011272924.1 - 0.16 12.5 0.0 0.33 11.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Inositol_P PF00459.20 XP_011272925.1 - 8.4e-66 222.0 0.0 9.2e-66 221.9 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family MAGE PF01454.14 XP_011272926.1 - 9.9e-30 103.3 2.6 1.6e-29 102.6 1.3 1.6 2 0 0 2 2 2 1 MAGE family FAD_binding_1 PF00667.15 XP_011272927.1 - 9.2e-65 218.1 0.0 5e-64 215.7 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Flavodoxin_1 PF00258.20 XP_011272927.1 - 1.8e-27 96.1 0.6 4e-27 94.9 0.4 1.7 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 XP_011272927.1 - 1.7e-23 83.2 0.1 1.7e-22 80.0 0.0 2.4 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 XP_011272927.1 - 0.00047 20.1 0.0 0.0013 18.7 0.0 1.8 1 0 0 1 1 1 1 Flavodoxin domain DUF948 PF06103.6 XP_011272927.1 - 0.69 9.8 2.6 23 4.9 0.1 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Xpo1 PF08389.7 XP_011272928.1 - 1.2e-05 25.2 6.7 3.8e-05 23.6 2.5 3.5 3 1 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.14 XP_011272928.1 - 8.7e-05 22.3 0.6 0.00042 20.1 0.4 2.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain Brix PF04427.13 XP_011272929.1 - 3.1e-42 144.4 0.9 4.3e-42 143.9 0.6 1.2 1 0 0 1 1 1 1 Brix domain UPF0029 PF01205.14 XP_011272929.1 - 0.055 13.1 0.1 0.096 12.3 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein family UPF0029 Peptidase_C3 PF00548.15 XP_011272929.1 - 0.058 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 3C cysteine protease (picornain 3C) MRP-S26 PF14943.1 XP_011272929.1 - 5.9 6.4 14.7 6.1 6.3 8.3 2.0 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 Ins_P5_2-kin PF06090.7 XP_011272930.1 - 2.1e-40 138.6 8.6 7.5e-39 133.6 5.9 2.1 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Peptidase_C4 PF00863.14 XP_011272930.1 - 0.25 10.2 5.5 0.13 11.1 2.1 1.8 2 0 0 2 2 2 0 Peptidase family C4 MaoC_dehydratas PF01575.14 XP_011272931.1 - 3.9e-05 23.0 0.0 8.5e-05 21.9 0.0 1.5 2 0 0 2 2 2 1 MaoC like domain Fic_N PF13784.1 XP_011272932.1 - 0.17 11.7 0.7 19 5.2 0.0 2.3 1 1 1 2 2 2 0 Fic/DOC family N-terminal DnaJ PF00226.26 XP_011272933.1 - 1e-10 41.1 1.3 1e-10 41.1 0.9 2.0 2 0 0 2 2 2 1 DnaJ domain Cytochrom_B562 PF07361.6 XP_011272933.1 - 3.5 8.0 11.2 0.21 12.0 4.0 1.8 2 0 0 2 2 2 0 Cytochrome b562 PTH2 PF01981.11 XP_011272934.1 - 6.6e-45 151.5 0.3 8.7e-45 151.1 0.2 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Protocadherin PF08374.6 XP_011272934.1 - 0.1 12.2 0.4 0.15 11.6 0.3 1.2 1 0 0 1 1 1 0 Protocadherin SEP PF08059.8 XP_011272935.1 - 6.1e-26 90.5 0.0 2.3e-25 88.7 0.0 2.1 1 0 0 1 1 1 1 SEP domain UBX PF00789.15 XP_011272935.1 - 1.4e-11 44.3 2.1 7.2e-11 41.9 0.0 3.1 3 0 0 3 3 3 1 UBX domain Meth_synt_2 PF01717.13 XP_011272936.1 - 1.1e-140 468.2 0.0 4.6e-136 453.0 0.0 3.1 3 1 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 XP_011272936.1 - 5.4e-127 423.3 0.1 1.4e-115 385.8 0.0 3.2 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain RICTOR_N PF14664.1 XP_011272937.1 - 4e-87 292.2 6.9 4.4e-86 288.8 4.7 2.2 1 1 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 XP_011272937.1 - 1.3e-71 240.2 1.5 1.3e-71 240.2 1.0 4.7 6 0 0 6 6 6 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_V PF14668.1 XP_011272937.1 - 8.2e-28 96.1 0.2 4.4e-26 90.6 0.0 3.3 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, domain 5 RasGEF_N_2 PF14663.1 XP_011272937.1 - 1.2e-20 73.5 0.1 8.7e-20 70.7 0.0 2.4 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain DUF2570 PF10828.3 XP_011272937.1 - 0.043 13.4 0.2 0.11 12.1 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) E1-E2_ATPase PF00122.15 XP_011272939.1 - 2.1e-61 206.9 7.2 2.1e-61 206.9 5.0 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 XP_011272939.1 - 2.3e-44 151.1 7.5 2.3e-44 151.1 5.2 1.8 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 XP_011272939.1 - 5.7e-35 121.6 0.4 6.7e-34 118.1 0.2 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 XP_011272939.1 - 3.7e-19 68.4 0.0 7.7e-19 67.4 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 XP_011272939.1 - 1.1e-18 68.1 0.0 2.5e-18 66.9 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 XP_011272939.1 - 6.4e-17 60.7 0.0 1.6e-16 59.5 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 XP_011272939.1 - 1.1e-08 34.9 0.5 0.0002 21.0 0.3 2.6 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase THF_DHG_CYH PF00763.18 XP_011272939.1 - 0.015 15.3 0.0 0.04 13.9 0.0 1.7 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain HAD_2 PF13419.1 XP_011272939.1 - 0.03 14.5 0.0 0.069 13.3 0.0 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 XP_011272939.1 - 0.089 12.6 0.0 0.35 10.7 0.0 2.0 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase IstB_IS21 PF01695.12 XP_011272939.1 - 0.12 11.8 0.0 0.4 10.0 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein Radical_SAM PF04055.16 XP_011272939.1 - 0.15 12.1 0.1 3 7.9 0.0 2.5 1 1 1 2 2 2 0 Radical SAM superfamily DUF792 PF05632.6 XP_011272940.1 - 0.042 13.1 0.0 0.063 12.6 0.0 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF792) Proteasome PF00227.21 XP_011272941.1 - 1.4e-39 135.4 0.0 1.5e-39 135.2 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Sec7 PF01369.15 XP_011272942.1 - 8.2e-33 113.6 4.2 8.2e-33 113.6 2.9 2.1 3 0 0 3 3 3 1 Sec7 domain Sipho_Gp157 PF05565.6 XP_011272942.1 - 0.0033 17.0 3.0 0.28 10.7 0.1 2.5 2 0 0 2 2 2 2 Siphovirus Gp157 PH_9 PF15410.1 XP_011272942.1 - 0.031 14.4 2.0 1.6 8.9 0.3 2.8 2 0 0 2 2 2 0 Pleckstrin homology domain Rad51 PF08423.6 XP_011272943.1 - 7.4e-142 470.7 0.0 8.9e-142 470.4 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 XP_011272943.1 - 2.4e-13 49.9 0.0 3.4e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 XP_011272943.1 - 7.1e-11 41.7 0.0 1e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.1 XP_011272943.1 - 6.9e-09 35.7 0.5 2.7e-08 33.8 0.4 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix domain KaiC PF06745.8 XP_011272943.1 - 1.1e-06 27.9 0.1 2.3e-06 26.8 0.0 1.5 1 1 0 1 1 1 1 KaiC AAA_22 PF13401.1 XP_011272943.1 - 0.023 14.8 0.0 0.045 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain DnaB_C PF03796.10 XP_011272943.1 - 0.028 13.2 0.1 0.057 12.2 0.1 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain PAXNEB PF05625.6 XP_011272943.1 - 0.088 11.6 0.3 0.18 10.6 0.1 1.5 2 0 0 2 2 2 0 PAXNEB protein Fungal_trans PF04082.13 XP_011272944.1 - 1.7e-26 92.6 1.4 1.7e-26 92.6 1.0 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 XP_011272944.1 - 1e-09 38.1 9.8 1.7e-09 37.4 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AhpC-TSA PF00578.16 XP_011272945.1 - 1.3e-32 112.1 0.0 1.7e-32 111.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.4 XP_011272945.1 - 6.8e-15 54.4 0.1 1.3e-14 53.5 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.5 XP_011272945.1 - 2.9e-10 39.8 0.0 4e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Redoxin Kinesin PF00225.18 XP_011272946.1 - 2.5e-113 378.1 2.3 2.5e-113 378.1 1.6 4.3 3 1 1 4 4 4 1 Kinesin motor domain Musclin PF11037.3 XP_011272946.1 - 0.2 11.2 5.5 0.06 12.9 0.8 2.4 2 1 1 3 3 3 0 Insulin-resistance promoting peptide in skeletal muscle Sel1 PF08238.7 XP_011272947.1 - 3e-38 129.3 13.0 5.4e-06 26.8 0.0 8.3 8 0 0 8 8 8 7 Sel1 repeat Pkinase PF00069.20 XP_011272948.1 - 7.9e-48 162.8 0.0 1.7e-47 161.7 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011272948.1 - 1.8e-20 73.1 0.0 3.1e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 XP_011272948.1 - 0.0022 17.0 0.0 0.0086 15.0 0.0 1.8 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 XP_011272948.1 - 0.003 16.9 0.2 0.01 15.2 0.0 2.0 1 1 1 2 2 2 1 RIO1 family APH PF01636.18 XP_011272948.1 - 0.031 13.9 0.0 0.37 10.5 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Actin PF00022.14 XP_011272949.1 - 4e-105 351.4 0.0 4.4e-105 351.3 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 XP_011272949.1 - 0.003 16.2 0.0 0.013 14.1 0.0 1.9 1 1 0 1 1 1 1 MreB/Mbl protein GCD14 PF08704.5 XP_011272951.1 - 1e-87 293.7 0.0 1.5e-87 293.1 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 XP_011272951.1 - 0.00076 19.0 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 XP_011272951.1 - 0.00079 19.0 0.0 0.0015 18.1 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.15 XP_011272951.1 - 0.021 13.8 0.0 0.05 12.6 0.0 1.5 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase Acyl-CoA_dh_1 PF00441.19 XP_011272952.1 - 6e-17 62.1 0.0 9.3e-17 61.5 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 XP_011272952.1 - 3e-11 42.6 0.2 6.5e-11 41.5 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 XP_011272952.1 - 2.5e-10 40.9 0.0 4.2e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 XP_011272952.1 - 0.0085 16.3 0.0 0.014 15.6 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain LSM PF01423.17 XP_011272953.1 - 7.4e-08 31.8 0.3 1.6e-07 30.7 0.2 1.5 1 0 0 1 1 1 1 LSM domain Helicase_C_2 PF13307.1 XP_011272953.1 - 0.11 12.4 0.1 0.86 9.5 0.0 2.1 2 0 0 2 2 2 0 Helicase C-terminal domain Involucrin2 PF06994.6 XP_011272953.1 - 0.5 10.3 3.9 0.91 9.5 2.7 1.3 1 0 0 1 1 1 0 Involucrin SUN PF03856.8 XP_011272954.1 - 2e-103 345.0 19.9 3e-103 344.4 13.8 1.3 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Macoilin PF09726.4 XP_011272954.1 - 0.62 8.2 10.2 0.67 8.1 7.1 1.1 1 0 0 1 1 1 0 Transmembrane protein SLD3 PF08639.5 XP_011272954.1 - 2.3 6.7 10.0 3.3 6.2 7.0 1.1 1 0 0 1 1 1 0 DNA replication regulator SLD3 Pho86 PF11124.3 XP_011272955.1 - 4.6e-71 239.3 6.9 5.5e-71 239.0 4.8 1.1 1 0 0 1 1 1 1 Inorganic phosphate transporter Pho86 Baculo_VP91_N PF08475.5 XP_011272955.1 - 0.0079 15.5 1.1 0.011 15.0 0.3 1.7 1 1 0 1 1 1 1 Viral capsid protein 91 N-terminal MORN_2 PF07661.8 XP_011272955.1 - 0.09 12.8 0.3 8.1 6.8 0.0 3.0 2 0 0 2 2 2 0 MORN repeat variant DUF1312 PF07009.6 XP_011272955.1 - 0.59 9.9 5.7 0.4 10.4 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1312) Lectin_leg-like PF03388.8 XP_011272956.1 - 6.7e-59 198.8 0.3 8.8e-59 198.4 0.2 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 XP_011272956.1 - 7.6e-07 28.7 0.1 0.005 16.2 0.1 2.3 2 0 0 2 2 2 2 Legume lectin domain Myc_N PF01056.13 XP_011272956.1 - 0.066 12.3 2.3 0.1 11.7 1.6 1.2 1 0 0 1 1 1 0 Myc amino-terminal region CDC45 PF02724.9 XP_011272956.1 - 0.087 10.8 6.9 0.12 10.3 4.8 1.1 1 0 0 1 1 1 0 CDC45-like protein His_Phos_1 PF00300.17 XP_011272957.1 - 2.6e-25 89.3 0.0 3.4e-25 88.9 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) YqbF PF14553.1 XP_011272957.1 - 7e-05 22.4 0.0 0.19 11.4 0.0 2.4 2 0 0 2 2 2 2 YqbF, hypothetical protein domain His_Phos_2 PF00328.17 XP_011272957.1 - 0.032 13.5 0.0 0.57 9.4 0.0 2.0 1 1 1 2 2 2 0 Histidine phosphatase superfamily (branch 2) Glyco_hydro_3 PF00933.16 XP_011272959.1 - 2.7e-84 282.6 0.0 3.9e-84 282.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 XP_011272959.1 - 3e-53 180.6 0.0 5e-53 179.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 XP_011272959.1 - 3.7e-24 84.4 0.1 8e-24 83.3 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain ARPC4 PF05856.7 XP_011272960.1 - 1.2e-54 184.2 5.4 1.3e-54 184.0 3.8 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) DUF3832 PF12909.2 XP_011272960.1 - 0.12 12.4 0.2 0.31 11.1 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3832) DUF3942 PF13078.1 XP_011272960.1 - 0.35 10.9 3.4 0.44 10.6 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3942) FF PF01846.14 XP_011272961.1 - 4.2e-41 138.6 36.5 3.4e-10 39.6 0.4 6.9 7 0 0 7 7 7 5 FF domain WW PF00397.21 XP_011272961.1 - 2.4e-19 68.8 11.4 6.2e-10 38.7 2.0 3.0 2 0 0 2 2 2 2 WW domain Peptidase_S24 PF00717.18 XP_011272962.1 - 1.5e-09 37.3 0.0 2.4e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like CobT_C PF11775.3 XP_011272962.1 - 0.071 12.5 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT VWA domain Ydc2-catalyt PF09159.5 XP_011272963.1 - 2e-53 181.6 0.3 2e-53 181.6 0.2 1.7 2 0 0 2 2 2 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Pox_A22 PF04848.8 XP_011272963.1 - 0.0038 17.0 0.3 0.41 10.5 0.1 3.1 2 1 0 2 2 2 1 Poxvirus A22 protein Npa1 PF11707.3 XP_011272965.1 - 2.5e-87 292.9 9.5 2.5e-87 292.9 6.6 3.8 4 0 0 4 4 4 1 Ribosome 60S biogenesis N-terminal Fungal_trans PF04082.13 XP_011272966.1 - 1.5e-23 83.0 0.6 3.3e-23 81.8 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain CCDC92 PF14916.1 XP_011272966.1 - 0.009 15.5 0.1 0.02 14.4 0.0 1.6 1 0 0 1 1 1 1 Coiled-coil domain of unknown function bZIP_1 PF00170.16 XP_011272966.1 - 0.0099 15.8 1.7 0.023 14.6 1.1 1.6 1 0 0 1 1 1 1 bZIP transcription factor NYD-SP28_assoc PF14775.1 XP_011272966.1 - 0.061 13.0 0.7 0.21 11.2 0.3 2.1 2 0 0 2 2 2 0 Sperm tail C-terminal domain HALZ PF02183.13 XP_011272966.1 - 0.24 11.1 1.7 0.56 9.9 1.2 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper SNAPc19 PF15497.1 XP_011272966.1 - 0.33 11.1 3.9 1.9 8.7 2.7 2.4 1 1 0 1 1 1 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 Mt_ATP-synt_D PF05873.7 XP_011272967.1 - 3e-20 72.4 1.9 3.7e-20 72.1 1.3 1.0 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) EzrA PF06160.7 XP_011272967.1 - 0.014 13.5 1.4 0.02 13.1 1.0 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Dor1 PF04124.7 XP_011272967.1 - 0.071 11.5 1.2 0.089 11.2 0.8 1.1 1 0 0 1 1 1 0 Dor1-like family Blo-t-5 PF11642.3 XP_011272967.1 - 0.14 11.9 2.2 0.22 11.3 1.5 1.3 1 0 0 1 1 1 0 Mite allergen Blo t 5 AAA_12 PF13087.1 XP_011272968.1 - 1e-58 198.0 0.3 4.8e-58 195.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 XP_011272968.1 - 2.3e-55 187.7 1.6 2.7e-55 187.5 0.2 1.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 XP_011272968.1 - 1.6e-13 50.1 0.0 4.7e-13 48.7 0.0 1.7 2 0 0 2 2 1 1 Part of AAA domain AAA_30 PF13604.1 XP_011272968.1 - 1.5e-09 37.7 0.0 5e-06 26.2 0.0 2.7 3 0 0 3 3 3 2 AAA domain UvrD-helicase PF00580.16 XP_011272968.1 - 1.1e-07 31.4 0.2 9.9e-07 28.3 0.1 2.2 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain ResIII PF04851.10 XP_011272968.1 - 2.4e-07 30.7 0.0 9.2e-07 28.8 0.0 2.0 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 XP_011272968.1 - 1.2e-06 28.2 0.1 0.13 11.7 0.0 3.4 3 1 0 3 3 3 2 Viral (Superfamily 1) RNA helicase PhoH PF02562.11 XP_011272968.1 - 7.6e-06 25.2 0.1 0.0011 18.2 0.0 3.0 3 0 0 3 3 3 1 PhoH-like protein AAA_22 PF13401.1 XP_011272968.1 - 0.00017 21.7 0.1 0.002 18.2 0.1 2.6 1 1 0 1 1 1 1 AAA domain DEAD PF00270.24 XP_011272968.1 - 0.00034 20.1 0.2 0.0037 16.7 0.0 2.2 1 1 1 2 2 2 1 DEAD/DEAH box helicase Zot PF05707.7 XP_011272968.1 - 0.00041 19.8 0.1 0.0017 17.8 0.0 2.1 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) DUF2075 PF09848.4 XP_011272968.1 - 0.0012 17.8 0.4 0.013 14.5 0.3 2.3 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.9 XP_011272968.1 - 0.0014 18.3 0.0 0.006 16.2 0.0 2.3 2 1 0 2 2 1 1 Helicase PIF1 PF05970.9 XP_011272968.1 - 0.0019 17.2 0.0 0.066 12.1 0.0 2.6 2 0 0 2 2 2 1 PIF1-like helicase AAA_14 PF13173.1 XP_011272968.1 - 0.0094 15.8 0.2 0.43 10.4 0.0 3.2 1 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 XP_011272968.1 - 0.014 15.1 0.0 0.079 12.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 XP_011272968.1 - 0.023 14.1 0.0 0.056 12.8 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein UvrD_C_2 PF13538.1 XP_011272968.1 - 0.027 14.5 0.2 0.46 10.6 0.0 2.8 3 0 0 3 3 2 0 UvrD-like helicase C-terminal domain AAA_25 PF13481.1 XP_011272968.1 - 0.043 13.2 0.0 0.14 11.5 0.0 1.9 2 1 0 2 2 2 0 AAA domain AAA PF00004.24 XP_011272968.1 - 0.051 13.7 1.7 0.3 11.3 1.0 2.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 XP_011272968.1 - 0.063 14.0 0.5 0.27 12.0 0.3 2.2 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 XP_011272968.1 - 0.076 12.9 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 XP_011272968.1 - 0.12 11.8 0.1 0.41 10.0 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family ArgK PF03308.11 XP_011272968.1 - 0.28 9.9 0.0 0.28 9.9 0.0 2.4 3 0 0 3 3 3 0 ArgK protein WD40 PF00400.27 XP_011272969.1 - 1.4e-18 65.9 1.6 1.9e-07 30.7 0.0 6.1 7 0 0 7 7 7 3 WD domain, G-beta repeat eIF2A PF08662.6 XP_011272969.1 - 3.5e-06 26.8 0.0 0.098 12.3 0.0 4.1 3 1 0 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 XP_011272969.1 - 0.034 12.3 0.1 0.067 11.3 0.0 1.6 2 1 0 2 2 2 0 Nucleoporin Nup120/160 K-box PF01486.12 XP_011272970.1 - 0.023 14.4 0.1 0.064 13.0 0.1 1.8 1 0 0 1 1 1 0 K-box region LRR_4 PF12799.2 XP_011272970.1 - 4.7 6.9 11.0 4.7 6.9 3.0 3.6 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) NDK PF00334.14 XP_011272971.1 - 5.7e-47 158.8 0.0 7.1e-47 158.5 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase C2 PF00168.25 XP_011272972.1 - 8.6e-52 172.9 1.3 4.1e-17 61.8 0.0 4.6 4 0 0 4 4 4 4 C2 domain DUF3987 PF13148.1 XP_011272972.1 - 6.3 5.2 4.8 9.5 4.6 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DNA_topoisoIV PF00521.15 XP_011272973.1 - 2.1e-126 422.2 0.2 4.2e-126 421.2 0.1 1.5 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 XP_011272973.1 - 3.1e-34 117.6 2.8 6.8e-34 116.5 2.0 1.6 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 XP_011272973.1 - 8.1e-13 48.2 0.0 3.5e-12 46.1 0.0 2.1 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 XP_011272973.1 - 1.4e-09 37.6 0.0 4e-09 36.1 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Mitofilin PF09731.4 XP_011272974.1 - 0.00025 19.8 25.8 0.00025 19.8 17.9 2.2 2 0 0 2 2 2 2 Mitochondrial inner membrane protein DUF3552 PF12072.3 XP_011272974.1 - 0.00025 20.3 9.3 0.00025 20.3 6.5 4.9 2 2 2 4 4 4 2 Domain of unknown function (DUF3552) Apolipoprotein PF01442.13 XP_011272974.1 - 0.0033 16.9 25.4 0.058 12.8 0.2 4.9 3 2 1 4 4 4 4 Apolipoprotein A1/A4/E domain DUF883 PF05957.8 XP_011272974.1 - 0.0088 16.4 36.9 2 8.9 0.2 7.4 3 3 5 8 8 8 3 Bacterial protein of unknown function (DUF883) HisKA_3 PF07730.8 XP_011272974.1 - 5.7 7.3 8.5 14 6.0 0.0 4.7 4 1 1 5 5 5 0 Histidine kinase DUF1752 PF08550.5 XP_011272975.1 - 5.4e-09 35.4 0.3 1.3e-08 34.2 0.2 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Vps16_N PF04841.8 XP_011272976.1 - 0.063 11.7 0.1 0.1 11.1 0.1 1.3 1 1 0 1 1 1 0 Vps16, N-terminal region Stork_head PF10264.4 XP_011272977.1 - 0.055 13.6 0.3 0.16 12.1 0.0 1.9 2 0 0 2 2 2 0 Winged helix Storkhead-box1 domain ABC2_membrane_4 PF12730.2 XP_011272978.1 - 0.0057 15.8 3.4 0.0057 15.8 2.3 1.4 1 1 0 1 1 1 1 ABC-2 family transporter protein DUF872 PF05915.7 XP_011272978.1 - 0.51 10.1 4.7 7.3 6.4 0.0 2.9 1 1 2 3 3 3 0 Eukaryotic protein of unknown function (DUF872) Brix PF04427.13 XP_011272980.1 - 5.1e-45 153.4 1.6 6.6e-45 153.1 1.1 1.1 1 0 0 1 1 1 1 Brix domain F-box-like PF12937.2 XP_011272982.1 - 1.1e-08 34.6 0.1 2.9e-08 33.3 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 XP_011272982.1 - 0.015 14.9 0.0 0.042 13.5 0.0 1.9 1 0 0 1 1 1 0 F-box domain DUF1751 PF08551.5 XP_011272983.1 - 2.6e-18 66.1 4.2 2.6e-18 66.1 2.9 2.6 3 0 0 3 3 3 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 XP_011272983.1 - 5.8e-05 23.1 8.7 5.8e-05 23.1 6.1 2.0 3 0 0 3 3 3 1 Rhomboid family DUF3357 PF11837.3 XP_011272983.1 - 0.013 15.3 0.2 1.7 8.5 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3357) Phage_lysozyme PF00959.14 XP_011272984.1 - 0.034 14.4 0.1 0.11 12.7 0.0 1.9 1 1 1 2 2 2 0 Phage lysozyme eIF3_p135 PF12807.2 XP_011272984.1 - 0.41 10.5 5.9 1.6 8.6 4.1 2.0 1 1 0 1 1 1 0 Translation initiation factor eIF3 subunit 135 PKK PF12474.3 XP_011272984.1 - 2.6 7.7 10.5 3.8 7.2 6.9 1.6 1 1 0 1 1 1 0 Polo kinase kinase Fungal_trans PF04082.13 XP_011272985.1 - 2.3e-27 95.5 4.3 2.3e-27 95.5 3.0 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 XP_011272985.1 - 0.00014 21.6 9.5 0.00029 20.6 6.0 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Joubert PF15392.1 XP_011272985.1 - 2.4 7.3 7.7 2.7 7.1 4.6 1.6 1 1 0 1 1 1 0 Joubert syndrome-associated SQS_PSY PF00494.14 XP_011272986.1 - 3.6e-40 137.9 0.0 4.5e-40 137.6 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase ABC2_membrane PF01061.19 XP_011272988.1 - 1.7e-77 259.3 39.2 2.6e-41 141.1 9.8 3.6 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 XP_011272988.1 - 8.8e-41 139.4 0.0 2.9e-19 69.7 0.1 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 XP_011272988.1 - 5.6e-39 131.9 3.7 2.9e-33 113.5 0.0 3.0 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.1 XP_011272988.1 - 5.3e-15 55.2 0.0 1.1e-14 54.2 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 XP_011272988.1 - 4.5e-08 32.5 43.0 3.2e-05 23.1 13.2 3.2 2 2 0 2 2 2 2 ABC-2 family transporter protein DUF258 PF03193.11 XP_011272988.1 - 2.5e-07 30.0 0.0 8.7e-05 21.7 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 XP_011272988.1 - 3.4e-07 29.8 0.0 0.00021 20.7 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 XP_011272988.1 - 4.5e-06 26.7 0.5 0.00019 21.4 0.1 2.8 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 XP_011272988.1 - 0.00012 22.2 0.0 0.037 14.1 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 XP_011272988.1 - 0.00014 21.7 0.0 0.1 12.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 XP_011272988.1 - 0.00026 20.2 0.0 0.42 9.8 0.0 3.2 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 XP_011272988.1 - 0.00051 19.5 0.3 0.057 12.9 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.1 XP_011272988.1 - 0.00054 20.0 0.0 0.27 11.1 0.0 3.5 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.7 XP_011272988.1 - 0.00057 19.0 0.0 0.44 9.5 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin cobW PF02492.14 XP_011272988.1 - 0.00098 18.6 0.0 0.0065 15.9 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Miro PF08477.8 XP_011272988.1 - 0.0012 19.3 0.0 2.6 8.5 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein NACHT PF05729.7 XP_011272988.1 - 0.0014 18.2 0.0 0.019 14.6 0.0 2.3 2 0 0 2 2 2 1 NACHT domain UPF0079 PF02367.12 XP_011272988.1 - 0.0016 18.0 0.7 0.033 13.8 0.2 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_17 PF13207.1 XP_011272988.1 - 0.0018 19.0 0.0 0.24 12.2 0.0 3.5 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.17 XP_011272988.1 - 0.0059 16.7 0.0 0.24 11.5 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.1 XP_011272988.1 - 0.01 16.1 0.0 0.16 12.2 0.0 2.8 3 0 0 3 3 2 0 AAA domain FtsK_SpoIIIE PF01580.13 XP_011272988.1 - 0.011 15.2 0.1 2.3 7.6 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 XP_011272988.1 - 0.022 14.7 0.0 0.85 9.5 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA PF00004.24 XP_011272988.1 - 0.048 13.8 0.0 6.2 7.0 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 XP_011272988.1 - 0.054 12.9 0.3 1.5 8.2 0.1 2.6 2 0 0 2 2 2 0 AAA-like domain Septin PF00735.13 XP_011272988.1 - 0.073 12.0 0.1 0.42 9.5 0.0 2.0 2 0 0 2 2 2 0 Septin AAA_30 PF13604.1 XP_011272988.1 - 0.075 12.6 0.3 2 7.9 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 XP_011272988.1 - 0.14 11.9 0.5 3.6 7.4 0.0 2.7 2 0 0 2 2 2 0 Part of AAA domain ABC2_membrane PF01061.19 XP_011272989.1 - 4.8e-73 244.7 44.2 6.8e-41 139.7 9.0 3.0 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 XP_011272989.1 - 1.5e-40 138.6 0.0 6.1e-19 68.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 XP_011272989.1 - 5.4e-39 131.9 2.7 7.7e-33 112.2 0.0 3.5 3 0 0 3 3 3 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 XP_011272989.1 - 1.1e-14 54.2 34.7 3.7e-11 42.6 6.5 2.8 2 1 0 2 2 2 2 ABC-2 family transporter protein ABC_trans_N PF14510.1 XP_011272989.1 - 1.8e-12 47.1 0.0 4.1e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal DUF258 PF03193.11 XP_011272989.1 - 1.1e-07 31.1 0.1 8.3e-05 21.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 XP_011272989.1 - 1.6e-07 30.8 0.0 0.0002 20.8 0.0 2.7 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 XP_011272989.1 - 6.7e-06 26.2 0.3 0.00019 21.5 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 XP_011272989.1 - 9.1e-05 22.3 0.0 0.079 12.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 XP_011272989.1 - 0.0002 20.6 0.0 0.42 9.8 0.0 3.1 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 XP_011272989.1 - 0.00029 20.9 0.0 0.049 13.7 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 XP_011272989.1 - 0.0007 19.0 0.5 0.058 12.9 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.1 XP_011272989.1 - 0.00086 19.3 0.3 0.34 10.8 0.0 3.6 4 0 0 4 4 3 1 AAA domain Zeta_toxin PF06414.7 XP_011272989.1 - 0.00088 18.4 0.0 0.39 9.7 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin NACHT PF05729.7 XP_011272989.1 - 0.0014 18.2 0.0 0.018 14.6 0.0 2.3 2 0 0 2 2 2 1 NACHT domain UPF0079 PF02367.12 XP_011272989.1 - 0.0023 17.5 0.8 0.033 13.8 0.2 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_17 PF13207.1 XP_011272989.1 - 0.0025 18.6 0.0 0.27 12.0 0.0 3.2 3 0 0 3 3 2 1 AAA domain Miro PF08477.8 XP_011272989.1 - 0.0032 17.9 0.0 4.9 7.6 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein cobW PF02492.14 XP_011272989.1 - 0.0035 16.7 0.0 0.017 14.5 0.0 2.0 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 XP_011272989.1 - 0.0047 17.2 0.1 0.15 12.3 0.0 2.9 3 0 0 3 3 2 1 AAA domain FtsK_SpoIIIE PF01580.13 XP_011272989.1 - 0.0095 15.4 0.3 2.3 7.6 0.0 2.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family RNA_helicase PF00910.17 XP_011272989.1 - 0.017 15.2 0.0 0.48 10.6 0.0 2.6 2 0 0 2 2 2 0 RNA helicase MMR_HSR1 PF01926.18 XP_011272989.1 - 0.022 14.7 0.0 0.97 9.4 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase Septin PF00735.13 XP_011272989.1 - 0.066 12.2 0.0 0.4 9.6 0.0 2.0 2 0 0 2 2 2 0 Septin AAA_10 PF12846.2 XP_011272989.1 - 0.073 12.4 0.2 1.5 8.1 0.1 2.3 2 0 0 2 2 2 0 AAA-like domain AAA_28 PF13521.1 XP_011272989.1 - 0.08 12.8 0.2 0.53 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 XP_011272989.1 - 0.1 12.1 0.4 2 7.9 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 XP_011272989.1 - 0.14 12.3 0.0 6.9 6.8 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 XP_011272989.1 - 0.15 11.8 0.7 3.5 7.4 0.0 2.8 2 0 0 2 2 2 0 Part of AAA domain NTPase_1 PF03266.10 XP_011272989.1 - 0.23 11.1 0.1 8.3 6.0 0.1 3.1 4 0 0 4 4 4 0 NTPase DUF3488 PF11992.3 XP_011272990.1 - 0.024 13.2 1.6 0.029 13.0 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) T_cell_tran_alt PF15128.1 XP_011272990.1 - 0.09 12.2 1.1 0.18 11.2 0.8 1.6 1 0 0 1 1 1 0 T-cell leukemia translocation-altered Sugar_tr PF00083.19 XP_011272991.1 - 9.6e-130 433.1 32.4 1.1e-129 432.9 22.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 XP_011272991.1 - 5.2e-32 110.9 46.6 1.1e-25 90.1 17.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Thioredoxin PF00085.15 XP_011272992.1 - 3.1e-57 190.6 0.4 1.4e-32 111.4 0.1 2.2 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.1 XP_011272992.1 - 3.2e-20 72.3 1.0 4.8e-10 39.6 0.0 3.1 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 XP_011272992.1 - 5e-17 61.8 2.5 1.2e-07 31.7 0.4 4.0 2 2 1 3 3 3 2 Thioredoxin-like Thioredoxin_7 PF13899.1 XP_011272992.1 - 1.5e-15 56.9 0.1 1.1e-06 28.5 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin-like Redoxin PF08534.5 XP_011272992.1 - 9.7e-14 51.1 0.4 2.9e-08 33.3 0.0 2.3 2 0 0 2 2 2 2 Redoxin ERp29 PF07749.7 XP_011272992.1 - 1.4e-12 48.0 0.8 5.8e-12 46.0 0.7 2.0 2 0 0 2 2 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain AhpC-TSA PF00578.16 XP_011272992.1 - 5e-09 35.8 0.5 0.00066 19.3 0.1 2.5 2 0 0 2 2 2 2 AhpC/TSA family ERp29_N PF07912.8 XP_011272992.1 - 1.3e-06 28.3 0.2 0.046 13.6 0.1 2.3 2 0 0 2 2 2 2 ERp29, N-terminal domain TraF PF13728.1 XP_011272992.1 - 4.1e-06 26.4 0.0 0.0076 15.7 0.0 2.5 2 0 0 2 2 2 2 F plasmid transfer operon protein Thioredoxin_3 PF13192.1 XP_011272992.1 - 4.6e-06 26.3 0.0 0.042 13.6 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin domain Thioredoxin_9 PF14595.1 XP_011272992.1 - 1.6e-05 24.4 0.0 0.021 14.3 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin HyaE PF07449.6 XP_011272992.1 - 3.6e-05 23.6 0.0 0.57 10.0 0.0 3.3 5 0 0 5 5 4 2 Hydrogenase-1 expression protein HyaE Thioredoxin_4 PF13462.1 XP_011272992.1 - 0.0077 16.2 3.0 0.63 10.0 0.0 3.4 3 2 1 4 4 4 1 Thioredoxin DDE_Tnp_1_2 PF13586.1 XP_011272992.1 - 0.049 13.8 0.0 2.5 8.3 0.0 3.2 3 0 0 3 3 3 0 Transposase DDE domain Glutaredoxin PF00462.19 XP_011272992.1 - 0.068 13.1 0.8 4.8 7.2 0.0 3.1 2 1 0 2 2 2 0 Glutaredoxin Mu-like_Com PF10122.4 XP_011272992.1 - 0.2 10.7 0.6 6.7 5.8 0.0 2.4 2 0 0 2 2 2 0 Mu-like prophage protein Com MFS_1 PF07690.11 XP_011272993.1 - 8.8e-24 83.8 36.8 2.3e-21 75.9 12.1 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Suc_Fer-like PF06999.7 XP_011272994.1 - 3.3e-44 151.6 0.0 5.1e-44 150.9 0.0 1.3 1 0 0 1 1 1 1 Sucrase/ferredoxin-like FoP_duplication PF13865.1 XP_011272995.1 - 0.0037 17.6 0.3 4 7.9 0.0 2.4 2 0 0 2 2 2 2 C-terminal duplication domain of Friend of PRMT1 rve_2 PF13333.1 XP_011272995.1 - 0.004 17.2 2.9 2.7 8.1 0.0 3.7 1 1 2 3 3 3 2 Integrase core domain DUF2872 PF11071.3 XP_011272995.1 - 0.014 15.2 1.7 1.3 8.9 0.1 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF2872) DUF4286 PF14114.1 XP_011272995.1 - 0.018 15.2 0.9 2.9 8.2 0.0 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4286) Cas_Csx9 PF09658.5 XP_011272995.1 - 0.029 13.1 0.8 2.7 6.6 0.1 2.2 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_Csx9) Phasin PF05597.6 XP_011272995.1 - 0.047 13.4 1.0 2.9 7.6 0.0 2.5 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) RE_MjaI PF09568.5 XP_011272995.1 - 0.059 12.9 2.4 2.5 7.6 0.3 2.3 1 1 1 2 2 2 0 MjaI restriction endonuclease DUF2164 PF09932.4 XP_011272995.1 - 0.064 13.0 0.2 4.1 7.2 0.1 2.6 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2164) DUF3235 PF11574.3 XP_011272995.1 - 0.09 13.0 0.0 3.8 7.8 0.0 2.7 1 1 1 3 3 3 0 Protein of unknown function (DUF3235) PTS_IIB PF02302.12 XP_011272995.1 - 0.13 12.7 0.2 6.3 7.3 0.0 2.8 3 0 0 3 3 3 0 PTS system, Lactose/Cellobiose specific IIB subunit YtxC PF08812.6 XP_011272995.1 - 0.22 11.0 6.6 1.7 8.0 0.5 2.3 1 1 1 2 2 2 0 YtxC-like family ADIP PF11559.3 XP_011272996.1 - 0.021 14.7 0.8 0.4 10.5 0.2 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding PUB PF09409.5 XP_011272996.1 - 0.024 14.3 0.1 0.037 13.7 0.1 1.2 1 0 0 1 1 1 0 PUB domain PaaSYMP PF14738.1 XP_011272996.1 - 0.036 13.7 0.6 0.049 13.3 0.5 1.2 1 0 0 1 1 1 0 Solute carrier (proton/amino acid symporter), TRAMD3 or PAT1 AAA_11 PF13086.1 XP_011272996.1 - 0.11 12.0 0.1 0.13 11.8 0.0 1.0 1 0 0 1 1 1 0 AAA domain PNPase PF03726.9 XP_011272996.1 - 0.11 12.7 0.5 0.17 12.1 0.3 1.3 1 0 0 1 1 1 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain ADH_zinc_N_2 PF13602.1 XP_011272997.1 - 5.8e-13 49.8 0.0 1.8e-12 48.2 0.0 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 XP_011272997.1 - 1.5e-11 43.9 0.0 2.5e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 XP_011272997.1 - 1.9e-06 27.6 0.0 3.5e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Semialdhyde_dh PF01118.19 XP_011272997.1 - 0.065 13.5 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.1 XP_011272998.1 - 5.8e-15 56.3 0.0 1.2e-14 55.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 XP_011272998.1 - 2.6e-13 49.6 0.0 5e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 XP_011272998.1 - 7.7e-06 25.6 0.0 1.4e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain THF_DHG_CYH_C PF02882.14 XP_011272998.1 - 0.038 13.0 0.0 0.059 12.4 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ApbA PF02558.11 XP_011272998.1 - 0.058 12.8 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Semialdhyde_dh PF01118.19 XP_011272998.1 - 0.11 12.8 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain SNF2_N PF00176.18 XP_011272999.1 - 1.3e-61 208.0 0.3 1.3e-61 208.0 0.2 2.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 XP_011272999.1 - 7.2e-15 54.6 1.1 2e-14 53.1 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.1 XP_011272999.1 - 3.2e-07 29.8 3.0 5.7e-07 29.1 2.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 XP_011272999.1 - 7.9e-07 28.9 5.3 1.7e-06 27.9 3.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 XP_011272999.1 - 8e-06 25.5 5.8 1.8e-05 24.4 4.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 XP_011272999.1 - 0.00015 21.3 5.8 0.00033 20.3 4.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 XP_011272999.1 - 0.00035 20.1 5.5 0.00078 19.0 3.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 XP_011272999.1 - 0.062 13.0 1.4 0.24 11.1 1.0 2.1 1 0 0 1 1 1 0 RING-type zinc-finger Cornichon PF03311.9 XP_011273000.1 - 7.5e-52 174.8 11.0 8.4e-52 174.6 7.6 1.0 1 0 0 1 1 1 1 Cornichon protein DUF4064 PF13273.1 XP_011273000.1 - 0.036 14.1 2.5 0.11 12.6 1.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) DUF1634 PF07843.6 XP_011273000.1 - 0.046 13.3 0.5 0.094 12.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1634) Claudin_3 PF06653.6 XP_011273000.1 - 2 8.1 7.4 0.12 12.0 1.0 1.9 1 1 0 2 2 2 0 Tight junction protein, Claudin-like Acid_PPase PF12689.2 XP_011273001.1 - 2.4e-15 56.5 1.6 6.1e-15 55.2 0.1 2.4 2 0 0 2 2 2 1 Acid Phosphatase Phage_lysis PF03245.8 XP_011273001.1 - 0.1 12.6 6.2 1.7 8.6 0.0 3.3 2 1 1 4 4 4 0 Bacteriophage Rz lysis protein Pyrophosphatase PF00719.14 XP_011273002.1 - 1.7e-52 177.0 0.2 2.2e-52 176.6 0.1 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase PRAI PF00697.17 XP_011273003.1 - 3.6e-52 176.7 0.1 1.5e-49 168.2 0.1 2.0 1 1 0 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase DUF3449 PF11931.3 XP_011273004.1 - 1.1e-73 246.9 4.4 1.1e-73 246.9 3.0 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF3449) zf-C2H2_jaz PF12171.3 XP_011273004.1 - 4.6e-09 36.1 7.6 2.6e-07 30.5 0.5 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 XP_011273004.1 - 5.9e-08 32.6 3.1 4.9e-05 23.3 0.4 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 XP_011273004.1 - 0.0018 18.3 9.2 0.0072 16.4 2.0 3.2 2 1 0 2 2 2 1 C2H2 type zinc-finger (2 copies) PyrI_C PF02748.10 XP_011273004.1 - 0.02 14.3 0.7 0.02 14.3 0.5 1.9 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Mitovir_RNA_pol PF05919.6 XP_011273004.1 - 0.19 10.6 16.8 0.095 11.6 2.8 2.1 2 0 0 2 2 2 0 Mitovirus RNA-dependent RNA polymerase zf-FCS PF06467.9 XP_011273004.1 - 0.23 11.1 2.6 8.6 6.0 0.1 2.5 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-U1 PF06220.7 XP_011273004.1 - 0.32 10.5 7.3 0.052 13.1 0.9 2.4 2 0 0 2 2 2 0 U1 zinc finger Nucleocapsid-N PF11030.3 XP_011273004.1 - 0.84 9.4 5.7 1.6 8.5 3.9 1.4 1 0 0 1 1 1 0 Nucleocapsid protein N zf-C2H2_4 PF13894.1 XP_011273004.1 - 1.4 9.4 6.6 16 6.1 0.1 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger Exo_endo_phos PF03372.18 XP_011273005.1 - 3.6e-14 53.3 0.0 4.3e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pyr_redox_2 PF07992.9 XP_011273006.1 - 6.5e-28 97.9 0.5 8.7e-19 68.1 0.0 3.2 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 XP_011273006.1 - 2e-10 40.9 0.2 1.5e-08 34.8 0.2 2.9 2 2 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 XP_011273006.1 - 5.9e-09 36.2 0.1 1.9e-05 24.8 0.0 3.4 3 1 1 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase MgtE PF01769.11 XP_011273007.1 - 0.057 13.6 0.6 0.058 13.6 0.4 2.2 1 1 0 2 2 2 0 Divalent cation transporter RNase_T PF00929.19 XP_011273008.1 - 4.4e-22 79.1 0.0 6.8e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 XP_011273008.1 - 0.0017 17.8 0.1 0.0042 16.5 0.1 1.6 1 0 0 1 1 1 1 3'-5' exonuclease PAT1 PF09770.4 XP_011273008.1 - 0.028 12.6 22.9 0.037 12.2 15.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CtIP_N PF10482.4 XP_011273008.1 - 0.1 12.3 0.1 0.17 11.6 0.1 1.4 1 0 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain DUF2360 PF10152.4 XP_011273008.1 - 0.42 10.8 10.8 0.71 10.1 7.5 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Trypan_PARP PF05887.6 XP_011273008.1 - 0.46 10.3 5.5 0.71 9.6 3.8 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Sulfate_transp PF00916.15 XP_011273009.1 - 1.3e-86 290.1 3.4 2.7e-86 289.0 2.3 1.5 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 XP_011273009.1 - 2.9e-30 103.7 3.0 2.9e-30 103.7 2.1 2.5 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 XP_011273009.1 - 6.1e-09 35.3 0.0 1.3e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 XP_011273009.1 - 0.037 14.0 0.0 0.075 13.0 0.0 1.4 1 0 0 1 1 1 0 STAS domain Acetyltransf_1 PF00583.19 XP_011273010.1 - 2e-09 37.3 0.0 3.1e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 XP_011273010.1 - 8.5e-08 32.2 0.0 3.1e-07 30.4 0.0 1.9 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 XP_011273010.1 - 3.9e-05 23.5 0.0 0.0024 17.7 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 XP_011273010.1 - 0.066 13.3 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 XP_011273010.1 - 0.088 12.5 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein HhH-GPD PF00730.20 XP_011273011.1 - 1.6e-13 50.8 0.0 3.2e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein SusD-like_2 PF12771.2 XP_011273011.1 - 0.1 11.0 0.0 0.13 10.6 0.0 1.1 1 0 0 1 1 1 0 Starch-binding associating with outer membrane Asp_protease PF09668.5 XP_011273012.1 - 4.6e-54 181.2 0.0 7.2e-54 180.6 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 XP_011273012.1 - 3.7e-11 43.3 0.0 1e-10 41.9 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease ubiquitin PF00240.18 XP_011273012.1 - 3.7e-10 39.0 0.1 7.4e-10 38.0 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family gag-asp_proteas PF13975.1 XP_011273012.1 - 1.4e-07 31.1 0.0 3.1e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease UBA PF00627.26 XP_011273012.1 - 1.5e-07 31.0 0.0 3.4e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain RVP PF00077.15 XP_011273012.1 - 4e-07 29.8 0.1 1.4e-06 28.1 0.0 1.9 2 0 0 2 2 2 1 Retroviral aspartyl protease RVP_2 PF08284.6 XP_011273012.1 - 1.1e-06 28.5 0.0 2.2e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Adeno_PIX PF03955.9 XP_011273012.1 - 6.1 7.4 6.6 1.9 9.0 0.8 2.3 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) Y_phosphatase2 PF03162.8 XP_011273013.1 - 6.1e-44 149.2 0.0 7.3e-44 149.0 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family BSD PF03909.12 XP_011273014.1 - 9.1e-14 50.9 3.2 2.2e-13 49.7 2.2 1.7 1 0 0 1 1 1 1 BSD domain UCH PF00443.24 XP_011273015.1 - 2.9e-70 236.4 1.1 2.9e-70 236.4 0.8 2.1 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 XP_011273015.1 - 1.1e-26 93.9 0.1 2.7e-26 92.7 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.15 XP_011273015.1 - 6.3e-07 29.7 0.0 1.7e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain Zn-ribbon_8 PF09723.5 XP_011273015.1 - 0.1 12.5 1.0 7.2 6.6 0.3 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-RVT PF13966.1 XP_011273016.1 - 0.033 14.5 0.4 0.084 13.1 0.2 1.8 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase MFS_2 PF13347.1 XP_011273017.1 - 2.7e-06 26.0 7.5 5e-06 25.1 0.2 2.6 3 0 0 3 3 3 2 MFS/sugar transport protein DUF1228 PF06779.9 XP_011273017.1 - 0.044 13.7 0.8 0.23 11.5 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1228) Aldedh PF00171.17 XP_011273018.1 - 6.2e-101 337.9 0.0 7.2e-101 337.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Adaptin_N PF01602.15 XP_011273019.1 - 3.9e-105 352.1 6.3 5.1e-105 351.7 4.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 XP_011273019.1 - 1.5e-09 37.9 4.3 9.4e-08 32.2 0.0 4.6 6 0 0 6 6 5 1 HEAT repeats HEAT PF02985.17 XP_011273019.1 - 9.7e-09 34.5 0.2 1.4 9.1 0.0 4.9 4 0 0 4 4 4 3 HEAT repeat HEAT_EZ PF13513.1 XP_011273019.1 - 1.7e-06 28.3 1.6 0.00017 21.9 0.0 3.8 4 0 0 4 4 4 1 HEAT-like repeat SPG48 PF14764.1 XP_011273019.1 - 4.7e-06 25.3 0.1 0.028 12.9 0.0 2.3 2 0 0 2 2 2 2 AP-5 complex subunit, vesicle trafficking Cnd1 PF12717.2 XP_011273019.1 - 8.9e-06 25.6 1.1 0.00078 19.3 0.1 3.6 2 1 2 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.2 XP_011273019.1 - 0.0015 18.4 0.0 0.016 15.1 0.0 2.6 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion HTH_36 PF13730.1 XP_011273019.1 - 0.0033 17.4 0.0 0.008 16.2 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain Herpes_BTRF1 PF04682.7 XP_011273019.1 - 0.016 14.5 0.5 0.047 13.0 0.3 1.8 1 1 0 1 1 1 0 Herpesvirus BTRF1 protein conserved region FANCI_S2 PF14676.1 XP_011273019.1 - 0.041 13.7 0.1 0.49 10.2 0.0 2.7 3 0 0 3 3 2 0 FANCI solenoid 2 RNA_pol_3_Rpc31 PF11705.3 XP_011273019.1 - 4.4 7.1 29.5 9.5 6.0 18.6 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 DUF2457 PF10446.4 XP_011273019.1 - 4.8 5.8 32.9 7.6 5.1 22.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PPP4R2 PF09184.6 XP_011273019.1 - 5.2 6.5 20.6 9.9 5.6 14.3 1.4 1 0 0 1 1 1 0 PPP4R2 NOA36 PF06524.7 XP_011273019.1 - 5.4 6.1 17.1 9.1 5.4 11.8 1.3 1 0 0 1 1 1 0 NOA36 protein SDA1 PF05285.7 XP_011273019.1 - 6.1 6.0 22.3 9 5.4 15.5 1.2 1 0 0 1 1 1 0 SDA1 HEAT_2 PF13646.1 XP_011273020.1 - 5.5e-19 68.2 0.2 0.00039 20.6 0.0 7.4 4 3 2 7 7 7 4 HEAT repeats HEAT PF02985.17 XP_011273020.1 - 2.2e-15 55.2 10.0 0.014 15.3 0.1 9.7 11 0 0 11 11 11 5 HEAT repeat HEAT_EZ PF13513.1 XP_011273020.1 - 7.4e-15 54.9 0.0 0.042 14.3 0.0 7.8 7 0 0 7 7 7 3 HEAT-like repeat Vac14_Fab1_bd PF12755.2 XP_011273020.1 - 3.2e-08 33.8 0.1 5.6 7.4 0.0 6.4 5 3 2 8 8 8 4 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 XP_011273020.1 - 2.8e-06 26.8 0.8 0.044 13.1 0.0 4.8 5 1 0 6 6 6 2 CLASP N terminal Arm PF00514.18 XP_011273020.1 - 1.3e-05 24.8 0.4 18 5.3 0.0 6.4 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat NUC173 PF08161.7 XP_011273020.1 - 0.00078 18.8 0.2 1.5 8.1 0.0 4.3 4 0 0 4 4 4 1 NUC173 domain MMS19_N PF14500.1 XP_011273020.1 - 0.017 14.3 1.1 0.77 8.9 0.0 3.5 5 0 0 5 5 5 0 Dos2-interacting transcription regulator of RNA-Pol-II Ipi1_N PF12333.3 XP_011273020.1 - 0.03 14.2 0.0 0.67 9.9 0.0 2.8 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation DUF2435 PF10363.4 XP_011273020.1 - 0.031 14.1 1.4 2 8.3 0.2 4.2 5 0 0 5 5 5 0 Protein of unknown function (DUF2435) Gpi16 PF04113.9 XP_011273021.1 - 4.4e-183 609.3 0.0 5.8e-183 608.9 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component Mad3_BUB1_I PF08311.7 XP_011273022.1 - 5e-41 139.4 1.1 1.4e-40 137.9 0.8 1.8 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 XP_011273022.1 - 2.8e-21 75.8 0.5 4.8e-21 75.0 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Mad3_BUB1_II PF08171.6 XP_011273022.1 - 3.3e-15 55.7 0.1 1.2e-14 53.9 0.0 2.0 1 0 0 1 1 1 1 Mad3/BUB1 homology region 2 Pkinase_Tyr PF07714.12 XP_011273022.1 - 0.00015 20.9 0.0 0.00026 20.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 XP_011273022.1 - 0.005 15.9 0.0 0.012 14.6 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 XP_011273022.1 - 0.092 11.6 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Peptidase_M1 PF01433.15 XP_011273023.1 - 4.7e-141 470.3 2.1 9.6e-141 469.3 1.5 1.5 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 XP_011273023.1 - 2.6e-95 319.4 2.0 2.9e-94 315.9 0.6 2.3 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 XP_011273023.1 - 5.1e-19 68.5 0.5 1e-18 67.6 0.4 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily DUF1360 PF07098.6 XP_011273023.1 - 0.15 11.7 0.5 0.35 10.6 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1360) Rotamase PF00639.16 XP_011273024.1 - 9.8e-26 90.3 0.1 1.4e-25 89.8 0.1 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 XP_011273024.1 - 4.8e-19 68.7 0.0 5.7e-19 68.5 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 XP_011273024.1 - 1.3e-05 24.9 1.5 2.6e-05 23.9 1.1 1.5 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.1 XP_011273024.1 - 2e-05 25.2 0.0 2.8e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain DUF2379 PF09543.5 XP_011273024.1 - 0.11 12.5 0.1 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2379) Acyl_CoA_thio PF02551.10 XP_011273025.1 - 9e-31 106.2 1.1 9.2e-21 73.8 0.2 3.2 2 1 0 2 2 2 2 Acyl-CoA thioesterase 4HBT_3 PF13622.1 XP_011273025.1 - 2.2e-27 96.4 0.0 2.7e-27 96.1 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily FTHFS PF01268.14 XP_011273026.1 - 1.4e-259 861.7 0.6 1.4e-259 861.7 0.4 1.4 2 0 0 2 2 2 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 XP_011273026.1 - 1.5e-63 212.7 0.6 3.6e-63 211.4 0.1 2.0 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 XP_011273026.1 - 9.9e-39 131.9 1.2 2.8e-38 130.5 0.8 1.9 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Prefoldin PF02996.12 XP_011273026.1 - 0.047 13.3 0.2 2.1 7.9 0.0 3.0 2 0 0 2 2 2 0 Prefoldin subunit Nuc_N PF14448.1 XP_011273026.1 - 0.071 12.6 0.0 0.3 10.6 0.0 2.0 1 0 0 1 1 1 0 Nuclease N terminal ABC2_membrane PF01061.19 XP_011273027.1 - 7.5e-86 286.6 56.9 2e-45 154.5 11.6 3.3 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 XP_011273027.1 - 4.6e-40 137.0 0.0 8.1e-20 71.5 0.0 2.7 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 XP_011273027.1 - 2.3e-35 120.3 1.9 3.8e-30 103.6 0.0 3.1 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.1 XP_011273027.1 - 5.8e-26 90.4 0.6 1.6e-25 88.9 0.1 2.1 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 XP_011273027.1 - 4e-08 32.8 0.4 9.3e-05 21.9 0.3 2.8 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 XP_011273027.1 - 6.5e-07 29.5 0.7 9.6e-05 22.4 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain ABC2_membrane_3 PF12698.2 XP_011273027.1 - 6.7e-07 28.6 27.8 0.0015 17.6 7.6 3.0 2 1 0 2 2 2 2 ABC-2 family transporter protein DUF258 PF03193.11 XP_011273027.1 - 1.7e-06 27.3 0.0 0.0016 17.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_33 PF13671.1 XP_011273027.1 - 3.3e-06 27.0 0.1 0.0037 17.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 XP_011273027.1 - 2e-05 23.9 0.4 0.008 15.6 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.14 XP_011273027.1 - 2.7e-05 23.6 1.3 0.01 15.2 0.1 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 XP_011273027.1 - 4e-05 23.9 0.8 0.02 15.1 0.0 3.2 3 0 0 3 3 2 1 AAA domain AAA_28 PF13521.1 XP_011273027.1 - 0.00034 20.6 0.6 0.039 13.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 XP_011273027.1 - 0.00041 21.1 0.0 0.2 12.4 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 XP_011273027.1 - 0.00052 20.1 0.2 0.69 10.0 0.1 3.1 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 XP_011273027.1 - 0.0007 19.2 0.3 0.98 9.0 0.0 2.8 2 0 0 2 2 2 2 NACHT domain AAA_19 PF13245.1 XP_011273027.1 - 0.00079 19.1 0.6 1.3 8.8 0.1 2.6 2 0 0 2 2 2 2 Part of AAA domain SMC_N PF02463.14 XP_011273027.1 - 0.0017 17.6 0.0 0.2 10.8 0.0 3.2 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 XP_011273027.1 - 0.0024 17.8 1.0 0.092 12.6 0.0 3.2 3 0 0 3 3 3 1 AAA domain UPF0079 PF02367.12 XP_011273027.1 - 0.012 15.2 1.0 2 8.0 0.2 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 XP_011273027.1 - 0.032 13.9 0.0 4.6 6.8 0.0 2.6 2 0 0 2 2 2 0 Archaeal ATPase AAA_30 PF13604.1 XP_011273027.1 - 0.048 13.2 0.2 4.5 6.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 XP_011273027.1 - 0.075 12.4 0.7 8 5.7 0.0 2.9 3 0 0 3 3 3 0 AAA-like domain MMR_HSR1 PF01926.18 XP_011273027.1 - 0.077 12.9 0.1 14 5.6 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA PF00004.24 XP_011273027.1 - 0.096 12.8 0.1 12 6.1 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Rhodanese PF00581.15 XP_011273028.1 - 1.7e-14 54.1 0.0 2e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain CTP_transf_2 PF01467.21 XP_011273029.1 - 1.1e-24 87.3 0.1 2.1e-24 86.3 0.0 1.5 1 0 0 1 1 1 1 Cytidylyltransferase Ribonuc_red_sm PF00268.16 XP_011273030.1 - 6.2e-122 406.0 3.0 7.9e-122 405.6 2.1 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain OPT PF03169.10 XP_011273031.1 - 1.4e-167 558.9 38.8 1.6e-167 558.7 26.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF605 PF04652.11 XP_011273032.1 - 3.7e-10 39.7 1.3 3.7e-10 39.7 0.9 3.3 2 1 1 4 4 4 2 Vta1 like EIF_2_alpha PF07541.7 XP_011273033.1 - 7.6e-42 141.6 0.3 3.1e-41 139.6 0.0 2.0 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 XP_011273033.1 - 4.1e-15 55.6 1.5 8.5e-15 54.6 1.0 1.6 1 0 0 1 1 1 1 S1 RNA binding domain Viral_env_E26 PF11050.3 XP_011273033.1 - 0.045 12.9 0.1 0.077 12.1 0.1 1.4 1 0 0 1 1 1 0 Virus envelope protein E26 EXOSC1 PF10447.4 XP_011273033.1 - 0.073 13.0 0.8 0.36 10.8 0.1 2.3 2 1 0 2 2 2 0 Exosome component EXOSC1/CSL4 CorA PF01544.13 XP_011273035.1 - 8.7e-06 24.9 9.7 2.1e-05 23.7 6.7 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein FTR1 PF03239.9 XP_011273036.1 - 1.3e-86 290.3 5.6 1.5e-86 290.1 3.9 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family DUF4418 PF14387.1 XP_011273036.1 - 8.7 6.1 8.1 1.2 8.8 0.1 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4418) Glyco_transf_15 PF01793.11 XP_011273037.1 - 2.2e-146 487.0 8.8 2.7e-146 486.7 6.1 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase VanY PF02557.12 XP_011273037.1 - 0.29 10.9 2.7 0.36 10.6 0.1 2.3 2 1 0 3 3 3 0 D-alanyl-D-alanine carboxypeptidase Dopey_N PF04118.9 XP_011273038.1 - 1.5e-106 355.6 0.3 6.9e-106 353.5 0.2 2.2 1 0 0 1 1 1 1 Dopey, N-terminal Abhydrolase_2 PF02230.11 XP_011273039.1 - 1.3e-52 178.3 0.0 1.6e-52 178.1 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 XP_011273039.1 - 2.3e-11 43.6 0.0 3.6e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 XP_011273039.1 - 4.7e-09 36.0 0.0 1.1e-08 34.7 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 XP_011273039.1 - 2.4e-07 30.8 0.0 4.3e-07 30.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 XP_011273039.1 - 1.1e-06 28.1 0.0 1.5e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.16 XP_011273039.1 - 0.0029 16.8 0.3 1.1 8.3 0.0 2.9 3 0 0 3 3 3 2 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 XP_011273039.1 - 0.019 14.5 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Mod_r PF07200.8 XP_011273040.1 - 3.3e-11 43.3 11.0 4.4e-11 42.9 7.6 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Reo_sigmaC PF04582.7 XP_011273040.1 - 0.011 14.9 2.8 0.012 14.7 2.0 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF4561 PF15120.1 XP_011273040.1 - 0.031 13.7 0.3 0.052 13.0 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4561) IncA PF04156.9 XP_011273040.1 - 0.04 13.5 7.0 0.053 13.1 4.9 1.2 1 0 0 1 1 1 0 IncA protein DUF1359 PF07097.6 XP_011273040.1 - 0.05 13.6 3.3 0.092 12.8 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1359) DUF2877 PF11392.3 XP_011273040.1 - 0.054 13.7 0.4 0.15 12.2 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2877) DENN PF02141.16 XP_011273040.1 - 0.11 12.1 1.1 0.21 11.2 0.4 1.7 1 1 0 1 1 1 0 DENN (AEX-3) domain Snapin_Pallidin PF14712.1 XP_011273040.1 - 3.1 8.1 10.9 6.2 7.2 2.5 2.6 1 1 2 3 3 3 0 Snapin/Pallidin WD40 PF00400.27 XP_011273041.1 - 4.9e-26 89.6 13.9 2.2e-06 27.3 0.1 6.6 6 1 0 6 6 6 6 WD domain, G-beta repeat KH_3 PF13014.1 XP_011273042.1 - 2.1e-16 59.1 1.2 0.00011 21.7 0.0 6.0 6 0 0 6 6 6 5 KH domain KH_1 PF00013.24 XP_011273042.1 - 7e-16 57.6 0.0 2.6e-08 33.3 0.0 5.9 6 0 0 6 6 6 3 KH domain DUF3834 PF12916.2 XP_011273042.1 - 0.028 13.4 0.2 0.06 12.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3834) WYL PF13280.1 XP_011273042.1 - 0.084 12.7 0.1 0.42 10.4 0.0 2.0 2 0 0 2 2 2 0 WYL domain Phosphodiest PF01663.17 XP_011273043.1 - 2.1e-14 53.6 0.1 3.3e-14 52.9 0.1 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 XP_011273043.1 - 0.0017 17.8 0.9 0.0029 17.0 0.6 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Cellulase PF00150.13 XP_011273043.1 - 0.015 14.5 0.0 0.024 13.8 0.0 1.2 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) E1_dh PF00676.15 XP_011273043.1 - 0.027 13.1 0.1 0.045 12.4 0.1 1.2 1 0 0 1 1 1 0 Dehydrogenase E1 component Sulfatase PF00884.18 XP_011273043.1 - 0.059 12.5 0.1 0.1 11.7 0.1 1.4 1 0 0 1 1 1 0 Sulfatase TrbC_Ftype PF09673.5 XP_011273044.1 - 0.015 14.8 1.9 0.11 12.1 0.0 2.6 2 1 0 2 2 2 0 Type-F conjugative transfer system pilin assembly protein Transcrip_act PF04949.8 XP_011273044.1 - 0.016 14.7 0.1 0.035 13.7 0.1 1.5 1 0 0 1 1 1 0 Transcriptional activator DUF3319 PF11782.3 XP_011273044.1 - 0.27 11.0 2.3 0.28 10.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3319) NPR3 PF03666.8 XP_011273045.1 - 7.6e-146 486.2 5.8 7.6e-146 486.2 4.0 2.9 3 1 0 3 3 3 1 Nitrogen Permease regulator of amino acid transport activity 3 Dynamin_N PF00350.18 XP_011273046.1 - 1e-16 61.2 0.1 1e-16 61.2 0.1 2.7 4 0 0 4 4 4 1 Dynamin family MMR_HSR1 PF01926.18 XP_011273046.1 - 4.3e-09 36.3 0.1 2.8e-08 33.7 0.1 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 XP_011273046.1 - 3.1e-07 30.0 0.8 1.8e-06 27.5 0.5 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 XP_011273046.1 - 0.00068 20.1 1.0 0.14 12.6 0.1 3.5 2 1 0 2 2 2 1 Miro-like protein AAA_29 PF13555.1 XP_011273046.1 - 0.046 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain PglZ PF08665.7 XP_011273046.1 - 0.11 12.1 0.1 0.11 12.1 0.1 2.7 3 0 0 3 3 3 0 PglZ domain AAA_17 PF13207.1 XP_011273046.1 - 0.11 13.2 1.1 0.45 11.3 0.0 2.7 3 0 0 3 3 3 0 AAA domain DUF3756 PF12581.3 XP_011273046.1 - 0.14 11.8 0.2 0.28 10.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3756) PAXNEB PF05625.6 XP_011273047.1 - 8.1e-111 370.3 1.4 1e-110 370.0 1.0 1.0 1 0 0 1 1 1 1 PAXNEB protein Nop14 PF04147.7 XP_011273048.1 - 0.0052 14.7 23.9 0.0072 14.3 16.6 1.2 1 0 0 1 1 1 1 Nop14-like family CENP-T PF15511.1 XP_011273048.1 - 0.29 10.3 19.0 0.42 9.7 13.2 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T SDA1 PF05285.7 XP_011273048.1 - 0.51 9.5 25.2 0.9 8.7 17.5 1.3 1 0 0 1 1 1 0 SDA1 PPP4R2 PF09184.6 XP_011273048.1 - 3.4 7.1 21.0 6.5 6.2 14.6 1.4 1 0 0 1 1 1 0 PPP4R2 CDC45 PF02724.9 XP_011273048.1 - 6.5 4.6 20.3 9.6 4.1 14.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Abhydrolase_6 PF12697.2 XP_011273049.1 - 3.1e-22 79.5 0.0 4.3e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 XP_011273049.1 - 4.2e-11 42.8 0.0 8.1e-11 41.9 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 XP_011273049.1 - 4.3e-08 33.0 0.0 6.8e-08 32.3 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 XP_011273049.1 - 8.8e-05 22.1 0.0 0.00017 21.2 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 XP_011273049.1 - 0.0002 20.7 0.0 0.00034 19.9 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Thioesterase PF00975.15 XP_011273049.1 - 0.0057 16.9 0.0 0.018 15.2 0.0 1.8 2 0 0 2 2 2 1 Thioesterase domain Ndr PF03096.9 XP_011273049.1 - 0.052 12.0 0.0 0.088 11.2 0.0 1.3 1 0 0 1 1 1 0 Ndr family DUF915 PF06028.6 XP_011273049.1 - 0.052 12.6 0.0 4.4 6.3 0.0 2.4 1 1 1 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) DUF726 PF05277.7 XP_011273049.1 - 0.14 11.0 0.0 0.23 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF726) Abhydrolase_6 PF12697.2 XP_011273050.1 - 1.2e-26 94.0 0.0 1.6e-26 93.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 XP_011273050.1 - 1.8e-18 66.9 0.1 4.8e-18 65.5 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 XP_011273050.1 - 1.3e-10 41.1 0.0 1.9e-10 40.6 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 XP_011273050.1 - 0.00036 20.8 0.0 0.00049 20.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.8 XP_011273050.1 - 0.0011 18.5 0.0 0.0019 17.8 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Ndr PF03096.9 XP_011273050.1 - 0.004 15.6 0.0 0.0061 15.0 0.0 1.3 1 0 0 1 1 1 1 Ndr family Esterase PF00756.15 XP_011273050.1 - 0.014 14.8 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Lipase_3 PF01764.20 XP_011273050.1 - 0.014 14.9 0.0 0.029 14.0 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) BAAT_C PF08840.6 XP_011273050.1 - 0.042 13.5 0.0 0.12 12.0 0.0 1.7 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.11 XP_011273050.1 - 0.069 12.5 0.1 2.5 7.4 0.0 2.5 2 1 0 3 3 3 0 Phospholipase/Carboxylesterase tRNA-synt_2 PF00152.15 XP_011273051.1 - 4.8e-110 367.4 0.1 6.1e-110 367.1 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 XP_011273051.1 - 5.8e-06 26.0 0.0 1.3e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 XP_011273051.1 - 0.00097 18.7 0.1 0.0058 16.2 0.1 2.0 1 1 1 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.15 XP_011273051.1 - 0.024 13.8 0.0 0.086 12.0 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) WD40 PF00400.27 XP_011273052.1 - 2.2e-51 169.9 17.0 1e-10 41.0 0.0 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 XP_011273052.1 - 4.5e-10 39.5 1.3 0.0012 18.5 0.0 4.1 2 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 XP_011273052.1 - 1.1e-09 37.0 2.4 0.035 12.2 0.1 4.8 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.9 XP_011273052.1 - 5.8e-05 22.0 0.0 0.057 12.2 0.0 2.7 1 1 1 3 3 3 2 Coatomer WD associated region Gmad1 PF10647.4 XP_011273052.1 - 0.0002 20.8 0.0 0.00034 20.0 0.0 1.3 1 0 0 1 1 1 1 Lipoprotein LpqB beta-propeller domain VID27 PF08553.5 XP_011273052.1 - 0.00044 18.6 0.1 0.096 10.8 0.0 3.0 2 1 1 3 3 3 1 VID27 cytoplasmic protein PQQ_2 PF13360.1 XP_011273052.1 - 0.00093 18.7 0.6 0.035 13.5 0.3 3.2 2 1 0 2 2 2 1 PQQ-like domain Cytochrom_D1 PF02239.11 XP_011273052.1 - 0.0018 16.6 0.1 2 6.6 0.0 3.0 1 1 1 3 3 3 2 Cytochrome D1 heme domain BBS2_Mid PF14783.1 XP_011273052.1 - 0.0026 17.4 0.0 3.3 7.5 0.0 3.5 3 1 1 4 4 4 1 Ciliary BBSome complex subunit 2, middle region UMP1 PF05348.6 XP_011273053.1 - 1.1e-28 99.8 0.0 1.3e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 GYF PF02213.11 XP_011273054.1 - 7.8e-14 51.0 1.5 1.9e-13 49.7 1.0 1.7 1 0 0 1 1 1 1 GYF domain DUF501 PF04417.7 XP_011273054.1 - 0.058 13.2 0.3 0.22 11.3 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF501) Sec66 PF09802.4 XP_011273055.1 - 1.3e-63 213.8 1.0 1.6e-63 213.5 0.7 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 OspE PF02471.12 XP_011273055.1 - 0.018 14.9 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 Borrelia outer surface protein E DAG1 PF05454.6 XP_011273055.1 - 0.041 13.0 0.0 0.056 12.6 0.0 1.2 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) DUF1722 PF08349.6 XP_011273055.1 - 0.069 13.0 0.1 6.8 6.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) DUF4523 PF15023.1 XP_011273055.1 - 0.082 12.4 0.2 0.16 11.4 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4523) NPL4 PF05021.10 XP_011273056.1 - 1.3e-127 425.2 0.0 1.8e-127 424.7 0.0 1.2 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 XP_011273056.1 - 1.3e-68 229.3 1.0 1.9e-68 228.7 0.1 1.8 2 0 0 2 2 2 1 NPL4 family, putative zinc binding region DUF4451 PF14616.1 XP_011273056.1 - 0.077 12.7 1.4 0.15 11.8 1.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4451) HSP70 PF00012.15 XP_011273057.1 - 4.7e-159 530.1 3.2 4.7e-159 530.1 2.2 2.1 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 XP_011273057.1 - 9.5e-12 44.1 0.0 2.7e-11 42.6 0.0 1.6 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 XP_011273057.1 - 0.0015 18.3 9.4 0.035 13.9 1.3 4.1 2 2 0 2 2 2 2 Cell division protein FtsA Ketoacyl-synt_C PF02801.17 XP_011273057.1 - 0.005 16.6 0.0 0.042 13.6 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain DAO PF01266.19 XP_011273058.1 - 3e-26 92.2 0.0 3.8e-26 91.8 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 XP_011273058.1 - 4.7e-06 25.7 0.0 7e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 XP_011273058.1 - 2.1e-05 24.5 0.0 4.1e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 XP_011273058.1 - 2.6e-05 23.4 0.2 4.8e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 XP_011273058.1 - 8.6e-05 22.8 1.1 0.0002 21.7 0.8 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 XP_011273058.1 - 0.0001 22.2 0.9 0.00023 21.0 0.6 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 XP_011273058.1 - 0.00028 20.0 0.0 0.00041 19.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 XP_011273058.1 - 0.0003 19.7 0.1 0.00066 18.6 0.0 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_7 PF13241.1 XP_011273058.1 - 0.0027 17.9 0.0 0.0054 16.9 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding 3HCDH_N PF02737.13 XP_011273058.1 - 0.011 15.3 0.0 0.023 14.3 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 XP_011273058.1 - 0.019 14.0 0.0 0.026 13.6 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.9 XP_011273058.1 - 0.023 13.1 0.2 0.035 12.5 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Homeobox_KN PF05920.6 XP_011273058.1 - 0.032 13.9 0.0 0.08 12.6 0.0 1.6 1 0 0 1 1 1 0 Homeobox KN domain Lycopene_cycl PF05834.7 XP_011273058.1 - 0.034 13.0 0.0 0.048 12.5 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.1 XP_011273058.1 - 0.049 13.6 0.0 0.086 12.8 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 XP_011273058.1 - 0.093 12.1 1.2 0.13 11.7 0.0 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.9 XP_011273058.1 - 0.16 11.3 0.2 0.31 10.4 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pkinase PF00069.20 XP_011273059.1 - 2.6e-43 148.0 2.9 2.5e-24 85.8 1.8 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011273059.1 - 4.7e-17 61.9 0.3 1.7e-12 46.9 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 XP_011273059.1 - 0.01 14.6 0.2 0.021 13.6 0.1 1.5 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Rsd_AlgQ PF04353.8 XP_011273060.1 - 0.083 12.5 3.9 0.068 12.8 0.9 2.3 2 1 0 2 2 2 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ tRNA_synt_1c_R1 PF04558.10 XP_011273060.1 - 0.46 9.9 3.9 0.46 9.9 0.2 2.7 3 0 0 3 3 3 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 DUF3661 PF12400.3 XP_011273061.1 - 3.2e-38 130.7 12.2 5.2e-38 130.0 8.4 1.3 1 0 0 1 1 1 1 Vaculolar membrane protein RabGAP-TBC PF00566.13 XP_011273062.1 - 1.3e-54 184.8 2.4 1.3e-54 184.8 1.7 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Pex24p PF06398.6 XP_011273063.1 - 3.9e-60 203.5 24.1 4.9e-60 203.2 16.7 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Oxidored-like PF09791.4 XP_011273064.1 - 1.8e-25 88.1 1.6 3.5e-25 87.1 1.1 1.5 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal Glyco_hydro_72 PF03198.9 XP_011273065.1 - 2.8e-124 414.2 1.9 2.8e-124 414.2 1.3 1.4 2 0 0 2 2 2 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.12 XP_011273065.1 - 0.00042 19.3 0.0 0.0006 18.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase PF00150.13 XP_011273065.1 - 0.00045 19.4 0.0 0.0051 16.0 0.0 2.3 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Tmemb_cc2 PF10267.4 XP_011273065.1 - 0.0031 16.1 3.6 0.0043 15.6 2.5 1.1 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein MFS_1 PF07690.11 XP_011273066.1 - 1.7e-36 125.7 25.1 1.8e-36 125.5 16.7 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 XP_011273066.1 - 3.4e-11 42.3 12.2 3.4e-11 42.3 8.5 2.9 1 1 1 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 XP_011273066.1 - 0.003 15.8 3.1 0.003 15.8 2.1 1.4 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) GTP_CH_N PF12471.3 XP_011273067.1 - 2e-86 288.5 0.0 2.9e-86 288.0 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 XP_011273067.1 - 1.7e-16 59.9 0.0 2.6e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II HSP20 PF00011.16 XP_011273068.1 - 1.4e-12 47.3 0.5 2.5e-12 46.5 0.3 1.4 1 0 0 1 1 1 1 Hsp20/alpha crystallin family GTP_EFTU PF00009.22 XP_011273069.1 - 6e-46 156.2 0.1 1.5e-45 154.9 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 XP_011273069.1 - 7.8e-26 90.1 0.5 1.4e-25 89.2 0.3 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 XP_011273069.1 - 3.4e-07 30.2 0.1 7.8e-07 29.1 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 XP_011273069.1 - 0.00016 21.6 0.0 0.00046 20.1 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase CDC48_2 PF02933.12 XP_011273069.1 - 0.065 12.8 0.0 0.16 11.5 0.0 1.7 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 Mitofilin PF09731.4 XP_011273069.1 - 5.6 5.5 19.6 8.3 4.9 13.6 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein IPK PF03770.11 XP_011273070.1 - 3.3e-51 173.7 0.1 4.7e-51 173.2 0.1 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase SNARE PF05739.14 XP_011273071.1 - 3.5e-13 49.0 4.2 3.5e-13 49.0 2.9 2.5 2 1 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 XP_011273071.1 - 2.5e-07 30.8 20.0 6.8e-07 29.3 7.1 2.4 2 0 0 2 2 2 2 Syntaxin PTA_PTB PF01515.14 XP_011273071.1 - 0.008 15.2 2.6 0.015 14.4 1.8 1.5 1 0 0 1 1 1 1 Phosphate acetyl/butaryl transferase Herpes_US9 PF06072.6 XP_011273071.1 - 0.014 15.2 1.0 0.028 14.2 0.7 1.5 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 Gln-synt_C PF00120.19 XP_011273071.1 - 0.031 13.4 3.3 0.063 12.4 2.0 1.8 1 1 1 2 2 2 0 Glutamine synthetase, catalytic domain ETRAMP PF09716.5 XP_011273071.1 - 0.12 12.3 0.2 0.12 12.3 0.1 2.4 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF4094 PF13334.1 XP_011273071.1 - 0.24 11.7 0.2 0.24 11.7 0.2 3.3 1 1 2 4 4 4 0 Domain of unknown function (DUF4094) Striatin PF08232.7 XP_011273071.1 - 0.45 10.8 10.7 1.8 8.8 2.7 2.2 2 0 0 2 2 2 0 Striatin family Reo_sigmaC PF04582.7 XP_011273071.1 - 0.65 9.1 4.4 0.66 9.0 0.3 2.0 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Fic PF02661.13 XP_011273071.1 - 0.78 10.4 5.4 5.4 7.7 0.1 3.2 1 1 1 3 3 3 0 Fic/DOC family DUF3753 PF12575.3 XP_011273071.1 - 1.3 8.8 5.7 1.6 8.5 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) DUF1664 PF07889.7 XP_011273071.1 - 6.5 6.5 9.4 3.4 7.4 1.5 2.9 2 2 0 2 2 2 0 Protein of unknown function (DUF1664) Allexi_40kDa PF05549.6 XP_011273071.1 - 7.4 5.7 11.1 2.9 7.0 1.8 2.1 1 1 0 2 2 2 0 Allexivirus 40kDa protein DUF3708 PF12501.3 XP_011273071.1 - 7.8 6.2 14.2 5.3 6.8 1.8 2.7 2 2 1 3 3 3 0 Phosphate ATP-binding cassette transporter Aminotran_1_2 PF00155.16 XP_011273072.1 - 3.4e-34 118.3 0.0 3.9e-34 118.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Neisseria_TspB PF05616.8 XP_011273072.1 - 0.043 12.1 1.5 0.084 11.2 1.1 1.4 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein DAGK_cat PF00781.19 XP_011273073.1 - 2.2e-24 85.3 0.0 4.2e-24 84.4 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DUF3605 PF12239.3 XP_011273074.1 - 6.7e-44 149.5 0.6 8e-44 149.2 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) DUF3605 PF12239.3 XP_011273075.1 - 4.9e-46 156.4 1.3 5.8e-46 156.2 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) IlvC PF01450.14 XP_011273075.1 - 0.022 14.6 0.0 0.038 13.9 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Mem_trans PF03547.13 XP_011273076.1 - 4.7e-57 193.0 0.5 6.6e-57 192.5 0.4 1.2 1 0 0 1 1 1 1 Membrane transport protein F-box PF00646.28 XP_011273077.1 - 0.0061 16.1 2.9 0.02 14.5 0.1 2.8 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.2 XP_011273077.1 - 0.077 12.7 0.2 11 5.8 0.1 3.0 2 0 0 2 2 2 0 F-box-like F-box-like_2 PF13013.1 XP_011273077.1 - 0.12 12.1 0.2 2.7 7.7 0.0 2.2 2 0 0 2 2 2 0 F-box-like domain AA_permease PF00324.16 XP_011273078.1 - 1.1e-87 294.4 39.8 1.3e-87 294.1 27.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 XP_011273078.1 - 2.8e-24 85.4 41.4 3.5e-24 85.1 28.7 1.1 1 0 0 1 1 1 1 Amino acid permease AMP-binding PF00501.23 XP_011273080.1 - 4.8e-89 298.6 0.0 6.2e-89 298.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 XP_011273080.1 - 3.8e-19 69.4 1.7 7.4e-19 68.4 0.1 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Pyrid_oxidase_2 PF13883.1 XP_011273081.1 - 4.2e-47 160.0 0.0 6.6e-47 159.4 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PT-HINT PF07591.6 XP_011273081.1 - 0.086 12.7 1.4 0.16 11.8 0.9 1.4 1 0 0 1 1 1 0 Pretoxin HINT domain Mis14 PF08641.7 XP_011273082.1 - 4.7e-15 55.8 6.9 6.7e-15 55.3 4.8 1.2 1 0 0 1 1 1 1 Kinetochore protein Mis14 like Rhomboid PF01694.17 XP_011273082.1 - 0.0002 21.4 1.5 0.00028 20.9 1.0 1.3 1 0 0 1 1 1 1 Rhomboid family Effector_1 PF04518.7 XP_011273082.1 - 0.055 12.4 2.1 0.084 11.8 1.4 1.2 1 0 0 1 1 1 0 Effector from type III secretion system DUF244 PF03112.9 XP_011273082.1 - 0.24 10.9 6.1 0.25 10.8 2.7 2.1 2 0 0 2 2 2 0 Uncharacterized protein family (ORF7) DUF ATP-synt_C PF00137.16 XP_011273083.1 - 7.5e-26 89.8 21.8 1.6e-16 59.9 3.6 2.0 2 0 0 2 2 2 2 ATP synthase subunit C Polysacc_synt_3 PF13440.1 XP_011273083.1 - 0.071 12.5 4.3 0.038 13.4 0.4 2.1 1 1 1 2 2 2 0 Polysaccharide biosynthesis protein TIP49 PF06068.8 XP_011273084.1 - 3.5e-177 589.0 3.6 4.2e-177 588.8 2.5 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 XP_011273084.1 - 1.2e-08 35.1 3.1 3.5e-05 23.9 0.1 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 XP_011273084.1 - 1.2e-06 27.8 3.6 0.0024 16.9 0.0 3.1 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus DnaB_C PF03796.10 XP_011273084.1 - 3.8e-05 22.7 1.1 0.00011 21.2 0.1 2.1 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_16 PF13191.1 XP_011273084.1 - 4.7e-05 23.4 0.0 0.0012 18.8 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 XP_011273084.1 - 0.0001 22.4 0.1 0.064 13.3 0.0 2.6 1 1 1 2 2 2 2 AAA domain AAA_14 PF13173.1 XP_011273084.1 - 0.00015 21.6 0.7 4.8 7.1 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_5 PF07728.9 XP_011273084.1 - 0.011 15.4 0.2 2.1 8.1 0.0 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 XP_011273084.1 - 0.02 14.0 0.5 0.4 9.8 0.1 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 XP_011273084.1 - 0.026 13.9 0.1 0.052 12.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 XP_011273084.1 - 0.037 13.7 0.1 0.085 12.6 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_28 PF13521.1 XP_011273084.1 - 0.053 13.4 0.1 0.15 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 XP_011273084.1 - 0.073 12.5 0.0 1.5 8.2 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family Pkinase PF00069.20 XP_011273085.1 - 1.8e-43 148.5 0.1 1.2e-27 96.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011273085.1 - 3.1e-17 62.5 0.0 1.3e-10 40.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 XP_011273085.1 - 0.0015 17.6 0.0 0.0021 17.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 XP_011273085.1 - 0.053 13.2 0.0 0.12 12.0 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF3770 PF12603.3 XP_011273086.1 - 0.0024 17.0 0.9 0.0035 16.5 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3770) DUF3199 PF11436.3 XP_011273086.1 - 0.022 14.6 1.4 0.45 10.3 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3199) GLYCAM-1 PF05242.6 XP_011273086.1 - 0.022 14.6 0.9 0.041 13.8 0.6 1.4 1 0 0 1 1 1 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) HsbA PF12296.3 XP_011273086.1 - 0.038 13.8 0.1 0.057 13.2 0.1 1.4 1 1 0 1 1 1 0 Hydrophobic surface binding protein A Trigger_C PF05698.9 XP_011273086.1 - 0.044 13.6 0.8 0.087 12.6 0.6 1.5 1 1 0 1 1 1 0 Bacterial trigger factor protein (TF) C-terminus DUF3192 PF11399.3 XP_011273086.1 - 0.093 12.6 0.1 2.6 8.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3192) eIF-5_eIF-2B PF01873.12 XP_011273087.1 - 4.3e-45 152.4 0.3 6.6e-45 151.7 0.2 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 IF2_N PF04760.10 XP_011273087.1 - 0.008 15.8 0.0 0.045 13.4 0.0 2.3 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region DUF2664 PF10867.3 XP_011273087.1 - 0.026 15.1 0.8 0.062 13.9 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2664) zinc_ribbon_6 PF14599.1 XP_011273087.1 - 0.44 10.3 2.9 6.4 6.6 0.5 2.4 1 1 1 2 2 2 0 Zinc-ribbon GET2 PF08690.5 XP_011273087.1 - 0.62 9.2 4.8 0.96 8.6 3.3 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 Arc_trans_TRASH PF08394.5 XP_011273087.1 - 3.7 7.7 5.9 37 4.5 0.1 2.7 1 1 1 2 2 2 0 Archaeal TRASH domain Ank_5 PF13857.1 XP_011273088.1 - 6.7e-16 57.9 0.7 3.4e-08 33.4 0.1 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 XP_011273088.1 - 8.3e-16 58.1 0.8 1.8e-15 56.9 0.5 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 XP_011273088.1 - 3.8e-15 54.8 0.0 2.6e-07 30.1 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 XP_011273088.1 - 5.1e-13 49.1 0.1 1.5e-12 47.6 0.1 1.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 XP_011273088.1 - 1.8e-12 46.1 0.4 5.6e-05 23.0 0.0 3.3 4 0 0 4 4 4 2 Ankyrin repeat YycI PF09648.5 XP_011273088.1 - 0.045 13.2 3.7 0.089 12.2 2.6 1.5 1 1 0 1 1 1 0 YycH protein PqqD PF05402.7 XP_011273088.1 - 0.1 12.6 1.5 1 9.4 0.0 2.8 3 0 0 3 3 3 0 Coenzyme PQQ synthesis protein D (PqqD) DUF2435 PF10363.4 XP_011273089.1 - 6.7e-28 96.4 6.5 1.1e-27 95.7 0.5 3.9 3 1 0 3 3 3 1 Protein of unknown function (DUF2435) WW PF00397.21 XP_011273090.1 - 3.8e-07 29.8 0.8 8.3e-07 28.7 0.5 1.5 1 0 0 1 1 1 1 WW domain ABC2_membrane_3 PF12698.2 XP_011273090.1 - 4.7 6.1 12.8 5.8 5.8 8.9 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Ribosomal_S5 PF00333.15 XP_011273091.1 - 4e-19 68.1 0.8 7.3e-19 67.2 0.6 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 XP_011273091.1 - 2.6e-18 65.0 0.0 7.8e-18 63.5 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Lipoprotein_9 PF03180.9 XP_011273091.1 - 0.039 12.8 0.6 0.072 11.9 0.4 1.4 1 0 0 1 1 1 0 NLPA lipoprotein DUF3348 PF11828.3 XP_011273091.1 - 0.058 12.8 0.1 0.085 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3348) DUF2838 PF10998.3 XP_011273092.1 - 7.7e-40 135.2 15.8 7.7e-40 135.2 10.9 2.4 3 0 0 3 3 1 1 Protein of unknown function (DUF2838) DivIC PF04977.10 XP_011273092.1 - 0.001 18.5 0.0 0.001 18.5 0.0 2.1 2 0 0 2 2 2 1 Septum formation initiator Val_tRNA-synt_C PF10458.4 XP_011273092.1 - 0.018 15.1 0.3 0.047 13.7 0.2 1.7 1 0 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm Seryl_tRNA_N PF02403.17 XP_011273092.1 - 0.018 15.0 8.7 0.87 9.6 0.4 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain AKNA PF12443.3 XP_011273092.1 - 0.03 14.3 0.3 2.4 8.1 0.0 2.4 2 0 0 2 2 2 0 AT-hook-containing transcription factor Mnd1 PF03962.10 XP_011273092.1 - 0.056 13.0 1.9 1.4 8.5 0.2 2.1 2 0 0 2 2 2 0 Mnd1 family Paralemmin PF03285.10 XP_011273092.1 - 0.061 12.8 1.3 0.12 11.8 0.9 1.4 1 0 0 1 1 1 0 Paralemmin Fzo_mitofusin PF04799.8 XP_011273092.1 - 0.099 12.0 1.8 7.1 5.9 0.0 2.3 2 0 0 2 2 2 0 fzo-like conserved region DASH_Dad3 PF08656.5 XP_011273092.1 - 0.13 11.9 3.0 6.9 6.4 0.5 2.5 2 0 0 2 2 2 0 DASH complex subunit Dad3 DUF2681 PF10883.3 XP_011273092.1 - 0.14 12.3 0.0 0.14 12.3 0.0 2.5 3 0 0 3 3 2 0 Protein of unknown function (DUF2681) DUF342 PF03961.8 XP_011273092.1 - 0.34 9.2 4.1 0.31 9.3 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF342) DUF1049 PF06305.6 XP_011273092.1 - 0.35 10.3 5.0 9.1 5.8 0.5 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) V-ATPase_G PF03179.10 XP_011273092.1 - 0.46 10.7 5.6 3.3 8.0 0.4 2.3 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit DMPK_coil PF08826.5 XP_011273092.1 - 1.8 8.5 5.9 1.4 8.8 0.2 2.3 2 0 0 2 2 2 0 DMPK coiled coil domain like Spc24 PF08286.6 XP_011273092.1 - 6.3 6.5 12.5 0.48 10.1 0.8 2.9 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 Prefoldin_2 PF01920.15 XP_011273092.1 - 8.1 6.2 10.5 7.9 6.2 1.3 2.5 2 1 1 3 3 3 0 Prefoldin subunit Oxidored_FMN PF00724.15 XP_011273093.1 - 5.2e-104 347.9 0.0 5.9e-104 347.7 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF1479 PF07350.7 XP_011273094.1 - 6.4e-154 512.4 0.0 8.3e-154 512.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.8 XP_011273094.1 - 0.0069 16.4 0.0 0.23 11.4 0.0 2.3 2 0 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) PKD_channel PF08016.7 XP_011273094.1 - 0.028 12.8 0.0 0.044 12.2 0.0 1.2 1 0 0 1 1 1 0 Polycystin cation channel Zn_clus PF00172.13 XP_011273095.1 - 0.0049 16.7 9.4 0.011 15.6 6.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ctr PF04145.10 XP_011273096.1 - 2.1e-25 89.4 2.3 3.6e-25 88.6 1.6 1.4 1 0 0 1 1 1 1 Ctr copper transporter family DUF2207 PF09972.4 XP_011273096.1 - 0.27 9.7 1.8 0.25 9.8 0.6 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) BAR_2 PF10455.4 XP_011273097.1 - 3.7e-78 262.3 19.9 5.9e-78 261.6 13.8 1.3 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Sp100 PF03172.8 XP_011273097.1 - 0.26 11.2 3.9 6.7 6.7 0.2 2.8 1 1 0 2 2 2 0 Sp100 domain ApoLp-III PF07464.6 XP_011273097.1 - 0.35 10.9 17.7 0.19 11.7 2.4 3.3 3 0 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Ground-like PF04155.13 XP_011273097.1 - 1.3 9.3 3.5 21 5.4 0.0 3.3 3 1 0 3 3 3 0 Ground-like domain MIP PF00230.15 XP_011273100.1 - 2.9e-45 154.4 16.0 3.5e-45 154.2 11.1 1.0 1 0 0 1 1 1 1 Major intrinsic protein AhpC-TSA PF00578.16 XP_011273101.1 - 1.2e-26 92.8 0.0 1.8e-26 92.2 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 XP_011273101.1 - 5.4e-19 68.1 0.0 9.7e-19 67.3 0.0 1.3 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 XP_011273101.1 - 0.027 14.4 0.0 0.04 13.8 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme Alb1 PF09135.6 XP_011273102.1 - 3.5e-19 69.4 19.3 3.5e-19 69.4 13.4 1.5 1 1 0 1 1 1 1 Alb1 MSC PF09402.5 XP_011273102.1 - 0.012 14.3 5.1 0.015 13.9 3.5 1.1 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain His_Phos_2 PF00328.17 XP_011273102.1 - 1.1 8.5 8.9 1.4 8.2 6.2 1.1 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) CTI PF06934.6 XP_011273102.1 - 1.1 7.4 10.8 0.22 9.6 4.5 1.7 1 1 1 2 2 2 0 Fatty acid cis/trans isomerase (CTI) Calreticulin PF00262.13 XP_011273103.1 - 3.1e-151 503.2 13.0 3.9e-151 502.8 9.0 1.1 1 0 0 1 1 1 1 Calreticulin family Peptidase_U49 PF10463.4 XP_011273103.1 - 1.8 8.2 4.1 7.8 6.2 0.2 2.6 2 0 0 2 2 2 0 Peptidase U49 Myb_DNA-bind_6 PF13921.1 XP_011273104.1 - 3.3e-09 36.7 1.1 4e-09 36.4 0.1 1.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 XP_011273104.1 - 6.5e-05 22.8 0.1 0.00011 22.2 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain GCV_T PF01571.16 XP_011273105.1 - 3.7e-05 23.1 0.0 0.056 12.8 0.0 2.9 3 0 0 3 3 3 2 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 XP_011273105.1 - 0.00072 19.5 0.0 0.023 14.7 0.0 2.3 2 0 0 2 2 2 1 Glycine cleavage T-protein C-terminal barrel domain Ribosomal_S7 PF00177.16 XP_011273106.1 - 1.4e-38 131.8 2.6 1.4e-38 131.8 1.8 1.4 2 0 0 2 2 2 1 Ribosomal protein S7p/S5e Carn_acyltransf PF00755.15 XP_011273107.1 - 2.2e-92 310.0 0.0 2.7e-92 309.7 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Zn_clus PF00172.13 XP_011273108.1 - 3.8e-07 29.9 10.3 6.5e-07 29.1 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 XP_011273109.1 - 6.4e-22 77.7 37.2 1.3e-12 47.0 11.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 XP_011273109.1 - 9.1e-10 37.5 16.8 6.6e-07 28.0 0.5 2.1 2 0 0 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.19 XP_011273109.1 - 0.0025 16.4 4.2 0.0025 16.4 2.9 3.1 2 1 0 3 3 3 2 Sugar (and other) transporter DUF1604 PF07713.8 XP_011273110.1 - 0.0032 17.2 1.0 0.0032 17.2 0.7 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1604) ATP-synt_F6 PF05511.6 XP_011273110.1 - 0.099 12.5 5.5 0.22 11.4 0.4 2.9 1 1 2 3 3 3 0 Mitochondrial ATP synthase coupling factor 6 SPT6_acidic PF14632.1 XP_011273110.1 - 0.62 10.2 10.0 0.26 11.4 2.2 2.3 2 0 0 2 2 2 0 Acidic N-terminal SPT6 zf-DHHC PF01529.15 XP_011273111.1 - 1.9e-35 121.8 14.6 2.7e-35 121.3 10.1 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase TRM PF02005.11 XP_011273113.1 - 7.7e-138 459.4 0.0 9.9e-138 459.1 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.11 XP_011273113.1 - 5.2e-05 22.9 0.2 0.00011 21.8 0.1 1.5 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_31 PF13847.1 XP_011273113.1 - 0.00091 18.8 0.0 0.0018 17.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 XP_011273113.1 - 0.0028 17.0 0.1 0.0085 15.5 0.1 1.7 2 0 0 2 2 2 1 Conserved hypothetical protein 95 MTS PF05175.9 XP_011273113.1 - 0.014 14.7 0.1 0.03 13.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.2 XP_011273113.1 - 0.025 15.1 0.0 0.049 14.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PRKCSH-like PF12999.2 XP_011273114.1 - 9.8e-60 201.1 8.4 9.8e-60 201.1 5.8 2.5 3 1 1 4 4 4 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 XP_011273114.1 - 3.9e-42 143.3 0.7 1.1e-41 141.8 0.5 1.8 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Syntaxin-6_N PF09177.6 XP_011273114.1 - 0.87 10.0 13.1 6.7 7.1 0.1 4.5 3 1 0 3 3 3 0 Syntaxin 6, N-terminal NPV_P10 PF05531.7 XP_011273114.1 - 7.5 6.8 14.2 19 5.6 0.1 4.8 4 1 1 5 5 5 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.7 XP_011273114.1 - 8 6.2 15.9 1.4 8.7 1.9 3.6 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus CRF1 PF10380.4 XP_011273115.1 - 2.8e-29 101.9 6.2 2.8e-29 101.9 4.3 4.8 2 1 0 2 2 2 1 Transcription factor CRF1 Baculo_LEF-11 PF06385.7 XP_011273115.1 - 0.022 14.8 0.1 0.067 13.2 0.1 1.8 1 0 0 1 1 1 0 Baculovirus LEF-11 protein JAB PF01398.16 XP_011273116.1 - 1.2e-11 44.3 0.0 2.4e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 XP_011273116.1 - 9.4e-06 25.7 2.9 9.4e-06 25.7 2.0 1.6 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function ABC1 PF03109.11 XP_011273117.1 - 7.9e-28 96.8 0.9 2.3e-27 95.3 0.1 2.2 2 0 0 2 2 2 1 ABC1 family Pkinase PF00069.20 XP_011273117.1 - 0.069 12.2 0.8 0.12 11.5 0.1 1.7 2 0 0 2 2 2 0 Protein kinase domain APH PF01636.18 XP_011273117.1 - 0.21 11.3 0.0 0.36 10.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Peptidase_C31 PF05410.8 XP_011273119.1 - 0.056 13.3 0.0 0.16 11.8 0.0 1.7 2 0 0 2 2 2 0 Porcine arterivirus-type cysteine proteinase alpha WD40 PF00400.27 XP_011273123.1 - 2.9e-63 207.6 19.9 1.6e-09 37.3 0.0 11.8 11 1 0 11 11 11 10 WD domain, G-beta repeat Utp13 PF08625.6 XP_011273123.1 - 2.5e-44 150.3 0.0 4.4e-44 149.5 0.0 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 XP_011273123.1 - 5.4e-09 34.7 2.4 0.078 11.1 0.0 5.3 3 1 2 5 5 5 5 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 XP_011273123.1 - 1.2e-05 23.8 0.4 0.099 10.9 0.0 3.4 2 1 1 3 3 3 2 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 XP_011273123.1 - 0.2 10.3 6.0 4.6 5.8 0.2 4.1 2 2 2 4 4 4 0 Nup133 N terminal like Ribosomal_L6 PF00347.18 XP_011273124.1 - 4.4e-31 107.2 10.2 5.5e-17 62.0 2.7 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 PC4 PF02229.11 XP_011273124.1 - 0.039 13.1 0.2 0.16 11.2 0.0 2.1 3 0 0 3 3 3 0 Transcriptional Coactivator p15 (PC4) DUF2067 PF09840.4 XP_011273124.1 - 0.044 13.2 0.2 0.084 12.3 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2067) YbbR PF07949.7 XP_011273124.1 - 0.067 13.3 1.2 1.4 9.0 0.6 2.7 1 1 0 1 1 1 0 YbbR-like protein Hydrolase_6 PF13344.1 XP_011273125.1 - 1.9e-24 85.4 0.0 3.4e-24 84.6 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 XP_011273125.1 - 1.3e-13 50.4 0.0 5.4e-13 48.4 0.0 2.1 1 1 0 1 1 1 1 HAD-hyrolase-like RsbRD_N PF14361.1 XP_011273125.1 - 0.013 15.9 0.0 6.3 7.3 0.0 2.5 2 0 0 2 2 2 0 RsbT co-antagonist protein rsbRD N-terminal domain Hydrolase PF00702.21 XP_011273125.1 - 0.029 14.7 0.0 0.51 10.7 0.0 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase LysM PF01476.15 XP_011273125.1 - 0.098 12.5 0.0 2 8.3 0.0 2.9 3 0 0 3 3 3 0 LysM domain DUF1846 PF08903.6 XP_011273125.1 - 0.12 10.7 0.0 0.18 10.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1846) Steroid_dh PF02544.11 XP_011273126.1 - 8.3e-22 77.5 4.0 8.3e-22 77.5 2.8 1.5 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.8 XP_011273126.1 - 0.0031 17.5 2.9 0.02 15.0 0.2 2.3 2 0 0 2 2 2 1 Phospholipid methyltransferase LSM PF01423.17 XP_011273127.1 - 2e-13 49.6 3.9 3.1e-13 49.0 2.7 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 XP_011273127.1 - 0.0076 16.1 0.1 0.016 15.1 0.1 1.7 1 1 0 1 1 1 1 Ataxin 2 SM domain Dynactin_p22 PF07426.6 XP_011273127.1 - 0.06 12.6 0.3 0.12 11.6 0.2 1.5 1 1 0 1 1 1 0 Dynactin subunit p22 PRP38 PF03371.10 XP_011273128.1 - 1.7e-45 154.7 0.6 2.1e-45 154.4 0.4 1.0 1 0 0 1 1 1 1 PRP38 family Las1 PF04031.8 XP_011273129.1 - 3.4e-40 137.2 0.6 2.5e-39 134.3 0.0 2.1 2 0 0 2 2 2 1 Las1-like Adaptin_binding PF10199.4 XP_011273129.1 - 0.0031 17.8 0.0 0.0087 16.3 0.0 1.8 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 AAA_12 PF13087.1 XP_011273129.1 - 1.1 8.5 8.9 0.3 10.4 3.9 1.7 2 0 0 2 2 2 0 AAA domain DUF4163 PF13739.1 XP_011273129.1 - 4.5 8.1 16.5 0.059 14.1 3.0 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4163) Clathrin PF00637.15 XP_011273130.1 - 8.3e-19 67.6 5.0 8.3e-19 67.6 3.4 3.4 4 1 0 4 4 4 1 Region in Clathrin and VPS Vps39_1 PF10366.4 XP_011273130.1 - 0.0036 17.2 2.6 0.007 16.3 0.6 2.5 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 WD40 PF00400.27 XP_011273130.1 - 0.039 13.8 0.0 0.14 12.0 0.0 1.9 1 0 0 1 1 1 0 WD domain, G-beta repeat Sigma70_ner PF04546.8 XP_011273130.1 - 3 7.3 17.2 6.3 6.3 11.9 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region Vfa1 PF08432.5 XP_011273130.1 - 3.2 7.7 12.1 6.2 6.8 8.4 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Prothymosin PF03247.9 XP_011273130.1 - 3.9 7.6 34.5 8 6.6 23.9 1.5 1 0 0 1 1 1 0 Prothymosin/parathymosin family TRAP_alpha PF03896.11 XP_011273130.1 - 4.2 6.2 12.1 7.5 5.4 8.4 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Nop14 PF04147.7 XP_011273130.1 - 4.4 5.0 28.3 8.1 4.2 19.6 1.4 1 0 0 1 1 1 0 Nop14-like family NAD_kinase PF01513.16 XP_011273132.1 - 2.3e-66 223.4 0.0 3.2e-66 223.0 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase DUF4224 PF13986.1 XP_011273133.1 - 0.2 11.2 0.0 0.38 10.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4224) Vps35 PF03635.12 XP_011273136.1 - 2e-276 919.0 34.1 2.5e-276 918.7 23.6 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 6PF2K PF01591.13 XP_011273137.1 - 1.3e-77 259.8 4.2 5.7e-73 244.6 1.6 2.3 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 XP_011273137.1 - 3.3e-33 115.0 0.8 1.1e-32 113.3 0.0 2.1 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 XP_011273137.1 - 0.00049 19.9 1.4 0.0049 16.7 0.3 2.6 2 1 0 2 2 2 1 AAA domain Peptidase_S64 PF08192.6 XP_011273138.1 - 3.1e-189 630.7 24.2 1.4e-188 628.5 16.8 1.8 1 1 0 1 1 1 1 Peptidase family S64 Pam17 PF08566.5 XP_011273139.1 - 1.9e-68 229.5 0.4 2.3e-68 229.2 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 BPD_transp_2 PF02653.11 XP_011273139.1 - 0.0042 16.0 0.5 0.0057 15.6 0.3 1.1 1 0 0 1 1 1 1 Branched-chain amino acid transport system / permease component NAD_Gly3P_dh_N PF01210.18 XP_011273140.1 - 7.7e-49 165.4 0.1 1.4e-48 164.5 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 XP_011273140.1 - 4.7e-46 156.1 0.3 8.7e-46 155.3 0.2 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.12 XP_011273140.1 - 0.0052 17.1 0.0 3.8 8.0 0.0 2.5 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.16 XP_011273140.1 - 0.12 11.9 0.2 0.27 10.7 0.0 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain peroxidase PF00141.18 XP_011273141.1 - 1.4e-37 129.3 0.0 2.1e-37 128.8 0.0 1.2 1 0 0 1 1 1 1 Peroxidase eIF3_subunit PF08597.5 XP_011273141.1 - 0.0081 15.7 0.1 0.017 14.7 0.0 1.5 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit zf-RING_2 PF13639.1 XP_011273142.1 - 3.1e-05 23.6 7.9 9.1e-05 22.2 5.5 1.9 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 XP_011273142.1 - 0.03 14.4 3.7 0.067 13.2 2.6 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 XP_011273142.1 - 0.087 12.8 8.6 0.26 11.3 6.0 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 XP_011273142.1 - 1.8 8.2 11.1 4.5 6.9 7.7 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Syntaxin-6_N PF09177.6 XP_011273143.1 - 5.6 7.4 31.2 0.91 9.9 5.5 4.2 2 1 2 4 4 4 0 Syntaxin 6, N-terminal Flavin_Reduct PF01613.13 XP_011273144.1 - 5.5e-27 94.5 0.0 6.3e-27 94.3 0.0 1.0 1 0 0 1 1 1 1 Flavin reductase like domain Spc24 PF08286.6 XP_011273145.1 - 1.8 8.2 6.7 0.7 9.5 1.8 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 PseudoU_synth_1 PF01416.15 XP_011273146.1 - 1.4e-29 102.6 0.0 1.2e-17 64.1 0.0 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase DEAD PF00270.24 XP_011273147.1 - 1.4e-38 132.0 0.2 7.1e-38 129.7 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 XP_011273147.1 - 4.7e-22 77.6 0.0 5.8e-21 74.1 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 XP_011273147.1 - 3.4e-17 61.7 0.2 7.4e-17 60.6 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 XP_011273147.1 - 3.1e-06 27.1 0.0 3.1e-06 27.1 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 XP_011273147.1 - 0.046 13.8 0.1 0.52 10.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain FAD_binding_2 PF00890.19 XP_011273149.1 - 1.1e-73 248.5 0.0 1.2e-73 248.3 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 XP_011273149.1 - 1.2e-06 28.3 0.0 8.6e-05 22.4 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 XP_011273149.1 - 2.1e-06 27.7 0.2 0.0013 18.6 0.0 3.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 XP_011273149.1 - 2.2e-06 27.9 0.0 3.1e-05 24.1 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 XP_011273149.1 - 3.9e-06 25.9 0.0 0.0002 20.3 0.0 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 XP_011273149.1 - 4.7e-06 25.3 0.7 0.18 10.2 0.0 3.1 3 0 0 3 3 3 3 HI0933-like protein Thi4 PF01946.12 XP_011273149.1 - 0.00034 19.7 0.1 0.011 14.8 0.0 2.7 3 0 0 3 3 3 1 Thi4 family GIDA PF01134.17 XP_011273149.1 - 0.0004 19.3 1.1 0.32 9.7 0.0 2.7 3 0 0 3 3 3 2 Glucose inhibited division protein A FAD_oxidored PF12831.2 XP_011273149.1 - 0.0013 17.8 0.0 0.0027 16.8 0.0 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 XP_011273149.1 - 0.002 17.2 0.0 0.0035 16.4 0.0 1.4 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 XP_011273149.1 - 0.011 15.5 0.0 0.03 14.1 0.0 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding SUI1 PF01253.17 XP_011273151.1 - 4.6e-19 68.0 3.3 4.6e-19 68.0 2.3 1.9 2 1 0 2 2 2 1 Translation initiation factor SUI1 PH_BEACH PF14844.1 XP_011273151.1 - 0.019 14.8 0.3 0.029 14.1 0.2 1.3 1 0 0 1 1 1 0 PH domain associated with Beige/BEACH TnpV PF14198.1 XP_011273151.1 - 0.031 14.1 7.8 0.024 14.5 2.1 2.2 2 0 0 2 2 2 0 Transposon-encoded protein TnpV DUF808 PF05661.7 XP_011273151.1 - 0.087 11.6 2.2 0.1 11.3 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF808) OmpH PF03938.9 XP_011273151.1 - 0.31 10.9 9.2 0.69 9.8 6.4 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) PIN_2 PF10130.4 XP_011273151.1 - 1.4 8.9 4.6 13 5.7 3.2 2.2 1 1 0 1 1 1 0 PIN domain Cgr1 PF03879.9 XP_011273151.1 - 7.2 6.8 20.9 0.039 14.1 7.6 2.1 2 1 0 2 2 2 0 Cgr1 family RNase_PH PF01138.16 XP_011273153.1 - 2.7e-30 105.3 0.3 3.7e-30 104.9 0.2 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 XP_011273153.1 - 2e-07 30.8 0.0 4.2e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Mannosyl_trans PF05007.8 XP_011273154.1 - 4.4e-77 259.2 27.0 7.4e-77 258.4 18.7 1.4 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.8 XP_011273154.1 - 8.3e-12 44.6 36.3 8.3e-12 44.6 25.2 1.5 1 1 1 2 2 2 1 GPI transamidase subunit PIG-U DUF2029 PF09594.5 XP_011273154.1 - 7.3e-05 22.3 1.2 0.00016 21.2 0.8 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2029) DUF2358 PF10184.4 XP_011273154.1 - 0.022 14.6 0.7 0.061 13.2 0.3 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2358) Pyr_redox_2 PF07992.9 XP_011273155.1 - 1.2e-12 48.1 0.0 5.2e-12 46.0 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 XP_011273155.1 - 6e-11 42.5 0.1 4.4e-07 30.2 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 XP_011273155.1 - 0.01 14.7 0.8 1.3 7.7 0.0 2.7 1 1 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_9 PF13454.1 XP_011273155.1 - 0.067 12.9 0.0 2.9 7.6 0.0 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 XP_011273155.1 - 0.086 12.8 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Nbs1_C PF08599.5 XP_011273156.1 - 1.9 8.4 6.8 0.13 12.2 1.2 1.8 2 0 0 2 2 2 0 DNA damage repair protein Nbs1 DUF4207 PF13904.1 XP_011273156.1 - 4.1 6.6 14.3 7.7 5.8 9.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4207) Mito_carr PF00153.22 XP_011273157.1 - 4e-48 161.0 5.1 3.2e-16 58.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein P_gingi_FimA PF06321.6 XP_011273157.1 - 0.0027 16.9 0.1 0.0037 16.5 0.1 1.2 1 0 0 1 1 1 1 Major fimbrial subunit protein (FimA) Tim17 PF02466.14 XP_011273157.1 - 0.14 12.1 2.2 2.5 8.1 0.5 2.9 2 1 1 3 3 3 0 Tim17/Tim22/Tim23/Pmp24 family WH1 PF00568.18 XP_011273158.1 - 0.12 12.0 0.1 0.27 10.9 0.1 1.5 1 0 0 1 1 1 0 WH1 domain Mso1_Sec1_bdg PF14475.1 XP_011273159.1 - 3.8e-18 64.5 0.0 7.7e-18 63.6 0.0 1.5 1 0 0 1 1 1 1 Sec1-binding region of Mso1 PAT1 PF09770.4 XP_011273159.1 - 0.027 12.7 24.3 0.027 12.7 16.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4080 PF13311.1 XP_011273159.1 - 0.5 10.3 4.9 0.75 9.7 3.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4080) RFC1 PF08519.7 XP_011273159.1 - 0.53 10.0 8.6 0.042 13.6 2.1 1.9 1 1 1 2 2 2 0 Replication factor RFC1 C terminal domain Med15 PF09606.5 XP_011273159.1 - 0.88 7.6 37.6 1 7.4 26.1 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Ribosomal_L37 PF08561.5 XP_011273159.1 - 1.4 8.5 6.5 0.57 9.7 1.9 2.3 2 1 0 2 2 2 0 Mitochondrial ribosomal protein L37 Hid1 PF12722.2 XP_011273159.1 - 1.7 6.2 14.0 1.9 6.0 9.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ofd1_CTDD PF10637.4 XP_011273159.1 - 1.8 7.6 8.3 2.5 7.1 5.7 1.2 1 0 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term DNA_pol_viral_N PF00242.12 XP_011273159.1 - 2.9 6.8 18.7 3.8 6.4 12.9 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Paramyxo_ncap PF00973.14 XP_011273159.1 - 4.8 5.7 10.7 6.1 5.4 7.4 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Hydantoinase_B PF02538.9 XP_011273160.1 - 1e-214 713.6 0.2 1.3e-214 713.2 0.1 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 XP_011273160.1 - 3.5e-92 308.6 1.3 3.5e-92 308.6 0.0 1.7 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 XP_011273160.1 - 3.1e-57 192.9 2.6 7.6e-57 191.6 0.1 2.4 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region Proteasome_A_N PF10584.4 XP_011273160.1 - 0.065 12.5 0.0 1.1 8.6 0.0 2.4 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature Ninjurin PF04923.7 XP_011273163.1 - 0.03 14.0 0.4 0.043 13.5 0.3 1.4 1 0 0 1 1 1 0 Ninjurin DUF4167 PF13763.1 XP_011273165.1 - 0.081 12.9 1.1 0.13 12.2 0.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4167) RNase_T PF00929.19 XP_011273167.1 - 2.6e-20 73.3 0.3 3.2e-20 73.0 0.2 1.1 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 XP_011273167.1 - 0.00015 21.2 0.8 0.001 18.6 0.2 2.0 1 1 0 2 2 2 1 3'-5' exonuclease RNase_T PF00929.19 XP_011273168.1 - 3.7e-21 76.1 0.0 4.5e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 Exonuclease RNase_T PF00929.19 XP_011273169.1 - 3.7e-11 43.5 0.1 5.2e-10 39.8 0.0 2.1 1 1 0 1 1 1 1 Exonuclease RNase_T PF00929.19 XP_011273170.1 - 4.2e-18 66.1 0.0 5.5e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 Exonuclease RNase_T PF00929.19 XP_011273171.1 - 1.9e-19 70.5 0.5 3.7e-19 69.5 0.3 1.5 1 0 0 1 1 1 1 Exonuclease Med31 PF05669.7 XP_011273171.1 - 0.00096 18.8 7.6 0.0025 17.5 4.4 2.2 2 0 0 2 2 2 1 SOH1 PAT1 PF09770.4 XP_011273171.1 - 3.6 5.7 24.1 5.8 5.0 16.7 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RNase_T PF00929.19 XP_011273172.1 - 9.8e-19 68.2 0.0 2.4e-18 66.9 0.0 1.7 1 0 0 1 1 1 1 Exonuclease PLU-1 PF08429.6 XP_011273173.1 - 6.1e-54 183.1 7.3 6.1e-54 183.1 5.0 3.2 3 1 0 3 3 3 1 PLU-1-like protein ARID PF01388.16 XP_011273173.1 - 2.2e-22 78.6 0.5 9.1e-22 76.7 0.1 2.4 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain JmjC PF02373.17 XP_011273173.1 - 2.9e-17 62.9 1.3 8.3e-09 35.6 0.1 2.9 2 0 0 2 2 2 2 JmjC domain, hydroxylase JmjN PF02375.12 XP_011273173.1 - 5.9e-15 54.5 1.6 5.9e-15 54.5 1.1 2.1 2 0 0 2 2 2 1 jmjN domain PHD PF00628.24 XP_011273173.1 - 2.7e-08 33.3 11.4 5.4e-08 32.4 7.9 1.5 1 0 0 1 1 1 1 PHD-finger Cation_efflux PF01545.16 XP_011273174.1 - 1e-45 156.0 2.8 1.4e-45 155.6 2.0 1.1 1 0 0 1 1 1 1 Cation efflux family Polysacc_synt_4 PF04669.8 XP_011273175.1 - 8.3e-23 80.7 1.4 2.2e-21 76.1 1.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis MoCF_biosynth PF00994.19 XP_011273176.1 - 5.8e-34 116.5 0.0 8.5e-34 116.0 0.0 1.2 1 0 0 1 1 1 1 Probable molybdopterin binding domain DUF1188 PF06690.6 XP_011273176.1 - 0.04 13.0 0.2 0.061 12.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) AA_permease_2 PF13520.1 XP_011273177.1 - 6.1e-63 212.8 49.3 7.6e-63 212.5 34.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 XP_011273177.1 - 2.5e-16 59.1 43.8 3.4e-16 58.6 30.3 1.1 1 0 0 1 1 1 1 Amino acid permease TRP PF06011.7 XP_011273178.1 - 5.3e-145 483.3 31.8 8.9e-145 482.5 22.0 1.3 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 XP_011273178.1 - 5.8e-43 146.3 0.1 9.6e-43 145.6 0.1 1.4 1 0 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.10 XP_011273178.1 - 0.041 14.1 0.0 0.075 13.2 0.0 1.3 1 0 0 1 1 1 0 ML domain ELH PF02323.10 XP_011273178.1 - 0.056 12.5 3.0 0.095 11.8 2.1 1.4 1 0 0 1 1 1 0 Egg-laying hormone precursor DUF4293 PF14126.1 XP_011273181.1 - 9.9 6.0 15.0 2.2 8.1 5.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4293) Aha1_N PF09229.6 XP_011273182.1 - 0.062 13.1 1.3 0.64 9.8 0.1 2.1 2 0 0 2 2 2 0 Activator of Hsp90 ATPase, N-terminal Mso1_Sec1_bdg PF14475.1 XP_011273183.1 - 3.5e-18 64.7 0.0 7.4e-18 63.6 0.0 1.6 1 0 0 1 1 1 1 Sec1-binding region of Mso1 PAT1 PF09770.4 XP_011273183.1 - 0.024 12.8 21.7 0.024 12.8 15.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 XP_011273183.1 - 0.53 8.4 32.0 0.6 8.2 22.2 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Paramyxo_ncap PF00973.14 XP_011273183.1 - 2.1 6.9 8.2 2.8 6.5 5.7 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Hid1 PF12722.2 XP_011273183.1 - 5.1 4.6 12.3 5.6 4.5 8.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RTA1 PF04479.8 XP_011273185.1 - 2.1e-29 102.6 2.8 2.5e-29 102.4 0.4 1.9 2 0 0 2 2 2 1 RTA1 like protein SLAC1 PF03595.12 XP_011273185.1 - 0.023 13.3 1.9 0.025 13.2 0.5 1.6 1 1 1 2 2 2 0 Voltage-dependent anion channel DUF1673 PF07895.6 XP_011273185.1 - 0.048 13.1 1.1 0.06 12.8 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) MatE PF01554.13 XP_011273185.1 - 0.19 11.3 8.1 0.05 13.2 1.4 2.4 2 1 1 3 3 3 0 MatE DUF4451 PF14616.1 XP_011273186.1 - 0.00042 20.0 6.2 0.00089 19.0 3.4 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4451) HRXXH PF13933.1 XP_011273187.1 - 1.9e-64 217.4 0.1 2.3e-64 217.2 0.1 1.0 1 0 0 1 1 1 1 Putative peptidase family Corona_6B_7B PF03262.8 XP_011273187.1 - 0.11 11.7 0.2 0.19 10.9 0.2 1.4 1 0 0 1 1 1 0 Coronavirus 6B/7B protein FGGY_N PF00370.16 XP_011273188.1 - 4.1e-51 173.6 1.8 4.2e-48 163.7 1.3 3.2 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 XP_011273188.1 - 1.7e-47 161.6 0.1 6.2e-47 159.7 0.0 2.0 3 0 0 3 3 3 1 FGGY family of carbohydrate kinases, C-terminal domain ROK PF00480.15 XP_011273188.1 - 0.014 15.1 0.5 0.029 14.1 0.0 1.7 2 0 0 2 2 2 0 ROK family BcrAD_BadFG PF01869.15 XP_011273188.1 - 0.023 13.9 0.0 0.086 12.1 0.0 1.9 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family PIG-X PF08320.7 XP_011273188.1 - 0.047 12.9 0.0 0.085 12.1 0.0 1.3 1 0 0 1 1 1 0 PIG-X / PBN1 DUF3464 PF11947.3 XP_011273188.1 - 0.29 10.5 3.5 0.33 10.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3464) Gtr1_RagA PF04670.7 XP_011273189.1 - 1.9e-82 275.8 3.9 2.7e-82 275.4 2.7 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 XP_011273189.1 - 2.8e-05 23.5 0.3 7.4e-05 22.1 0.1 1.8 2 0 0 2 2 2 1 Ras family Miro PF08477.8 XP_011273189.1 - 5.4e-05 23.6 0.4 0.0013 19.2 0.1 2.3 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 XP_011273189.1 - 0.00012 21.4 0.8 0.00021 20.5 0.1 1.8 1 1 1 2 2 2 1 ADP-ribosylation factor family UPF0061 PF02696.9 XP_011273192.1 - 7e-132 440.1 0.2 8.5e-132 439.8 0.2 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family AHSP PF09236.5 XP_011273192.1 - 0.045 13.9 0.2 0.53 10.5 0.0 2.6 2 0 0 2 2 2 0 Alpha-haemoglobin stabilising protein HSDR_N_2 PF13588.1 XP_011273193.1 - 0.0037 17.0 2.7 0.045 13.5 1.9 2.4 1 1 0 1 1 1 1 Type I restriction enzyme R protein N terminus (HSDR_N) DUF1128 PF06569.6 XP_011273193.1 - 1.5 8.5 9.9 2.1 8.1 2.5 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1128) ECH PF00378.15 XP_011273194.1 - 1.1e-21 77.0 0.0 1.4e-21 76.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family PdxA PF04166.7 XP_011273194.1 - 0.066 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal phosphate biosynthetic protein PdxA Alba PF01918.16 XP_011273194.1 - 0.083 12.4 0.0 0.32 10.5 0.0 2.0 1 0 0 1 1 1 0 Alba DAO PF01266.19 XP_011273195.1 - 1.1e-28 100.1 0.0 5.2e-28 97.9 0.0 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 XP_011273195.1 - 0.0002 21.4 0.0 0.053 13.5 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 XP_011273195.1 - 0.00044 20.2 0.0 0.0027 17.6 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 XP_011273195.1 - 0.0098 15.7 0.0 0.038 13.8 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 XP_011273195.1 - 0.028 14.2 0.0 0.055 13.2 0.0 1.5 1 0 0 1 1 1 0 ThiF family Shikimate_DH PF01488.15 XP_011273195.1 - 0.083 12.9 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 XP_011273195.1 - 0.18 11.4 0.0 4.5 6.8 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Mid2 PF04478.7 XP_011273196.1 - 1.9e-08 33.8 2.5 1.9e-08 33.8 1.7 4.4 1 1 5 6 6 6 1 Mid2 like cell wall stress sensor TMEM154 PF15102.1 XP_011273196.1 - 0.01 15.5 2.6 0.01 15.5 1.8 4.3 1 1 2 3 3 3 0 TMEM154 protein family DUF912 PF06024.7 XP_011273196.1 - 0.34 11.0 0.0 0.34 11.0 0.0 5.0 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2407_C PF13373.1 XP_011273196.1 - 0.6 10.0 0.0 0.6 10.0 0.0 3.3 2 1 0 2 2 2 0 DUF2407 C-terminal domain zf-Tim10_DDP PF02953.10 XP_011273197.1 - 4.4e-21 73.9 1.7 5.4e-21 73.6 1.2 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF4215 PF13948.1 XP_011273197.1 - 0.1 12.8 3.1 0.15 12.2 2.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4215) Linker_histone PF00538.14 XP_011273197.1 - 0.15 12.1 0.4 0.22 11.6 0.2 1.3 1 1 0 1 1 1 0 linker histone H1 and H5 family DUF1767 PF08585.7 XP_011273197.1 - 0.2 11.9 1.3 0.7 10.2 0.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1767) PAPS_reduct PF01507.14 XP_011273199.1 - 9.1e-32 110.2 0.1 1.4e-28 99.9 0.0 2.3 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family zf-AD PF07776.10 XP_011273200.1 - 0.043 13.8 0.2 0.2 11.6 0.0 2.2 2 0 0 2 2 2 0 Zinc-finger associated domain (zf-AD) zf-met PF12874.2 XP_011273201.1 - 5.9e-06 26.2 0.6 3.5e-05 23.8 0.6 2.1 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-U1 PF06220.7 XP_011273201.1 - 0.039 13.5 0.2 0.084 12.4 0.1 1.6 1 0 0 1 1 1 0 U1 zinc finger Nuf2 PF03800.9 XP_011273202.1 - 8.6e-37 126.3 3.3 2.8e-36 124.6 2.3 1.8 1 0 0 1 1 1 1 Nuf2 family ApoO PF09769.4 XP_011273202.1 - 0.41 10.3 1.8 3 7.5 1.2 2.2 1 1 0 1 1 1 0 Apolipoprotein O Sdh5 PF03937.11 XP_011273203.1 - 9.3e-24 82.9 1.4 1.4e-23 82.3 1.0 1.3 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase HLH PF00010.21 XP_011273204.1 - 2.4e-16 59.1 0.4 8.9e-16 57.3 0.0 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Got1 PF04178.7 XP_011273205.1 - 1.8e-26 92.5 15.4 2.7e-26 92.0 10.6 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family NARP1 PF12569.3 XP_011273206.1 - 9.7e-127 423.8 17.9 9.7e-127 423.8 12.4 2.3 2 1 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_2 PF07719.12 XP_011273206.1 - 1.7e-12 46.2 13.9 0.0038 17.0 0.0 8.9 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.1 XP_011273206.1 - 3e-12 46.8 0.7 0.012 16.2 0.0 5.9 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 XP_011273206.1 - 1.1e-09 38.4 10.5 0.0066 16.7 0.4 6.2 6 1 0 6 6 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 XP_011273206.1 - 1.2e-09 37.9 1.2 0.031 14.8 0.0 6.7 5 2 3 8 8 8 1 Tetratricopeptide repeat TPR_11 PF13414.1 XP_011273206.1 - 2.1e-09 36.9 12.8 0.075 12.6 0.0 5.8 4 2 2 6 6 6 4 TPR repeat TPR_7 PF13176.1 XP_011273206.1 - 2.9e-05 23.5 0.9 9.3 6.3 0.0 5.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 XP_011273206.1 - 0.00012 21.5 11.9 0.25 10.9 0.0 6.7 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.1 XP_011273206.1 - 0.0014 18.6 7.9 24 5.4 0.0 7.4 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_6 PF13174.1 XP_011273206.1 - 0.015 15.6 5.2 0.64 10.5 0.0 5.5 6 0 0 6 6 5 0 Tetratricopeptide repeat EIAV_Rev PF11129.3 XP_011273206.1 - 0.036 14.0 0.1 0.093 12.7 0.1 1.6 1 0 0 1 1 1 0 Rev protein of equine infectious anaemia virus PPR_2 PF13041.1 XP_011273206.1 - 0.11 12.5 0.5 1.5 8.8 0.0 2.8 3 0 0 3 3 3 0 PPR repeat family Fis1_TPR_C PF14853.1 XP_011273206.1 - 0.31 10.9 5.8 1.6 8.6 0.4 3.6 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat Cyclin_N PF00134.18 XP_011273207.1 - 9.9e-22 76.8 0.0 2.3e-21 75.6 0.0 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 XP_011273207.1 - 4.3e-14 53.1 4.7 4.9e-13 49.7 0.0 2.3 2 0 0 2 2 2 1 Cyclin FMO-like PF00743.14 XP_011273208.1 - 7e-28 97.1 0.1 6.8e-12 44.3 0.1 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 XP_011273208.1 - 1.9e-15 57.4 0.1 2.9e-10 40.5 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 XP_011273208.1 - 1.4e-08 34.8 0.0 1.9e-07 31.1 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 XP_011273208.1 - 4e-07 29.2 2.1 0.01 14.7 0.2 3.6 3 1 2 5 5 5 3 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 XP_011273208.1 - 6.5e-07 29.2 1.1 3.8e-05 23.5 0.8 2.9 1 1 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 XP_011273208.1 - 0.00012 21.9 0.0 0.00029 20.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 XP_011273208.1 - 0.0012 17.8 0.0 0.0071 15.2 0.0 2.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 XP_011273208.1 - 0.15 12.4 0.3 5.9 7.3 0.1 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase TruB_N PF01509.13 XP_011273209.1 - 2.6e-43 147.7 1.0 6.6e-42 143.1 0.0 2.7 3 1 0 3 3 3 1 TruB family pseudouridylate synthase (N terminal domain) VirDNA-topo-I_N PF09266.5 XP_011273209.1 - 8.8 6.3 7.9 0.42 10.5 0.4 2.5 2 0 0 2 2 2 0 Viral DNA topoisomerase I, N-terminal Erf4 PF10256.4 XP_011273210.1 - 9.7e-18 64.1 0.1 1.5e-17 63.5 0.1 1.3 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family ubiquitin PF00240.18 XP_011273211.1 - 8.8e-05 21.8 0.2 0.0002 20.6 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 XP_011273211.1 - 0.0049 17.0 0.1 0.0079 16.3 0.1 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain RabGAP-TBC PF00566.13 XP_011273212.1 - 1.3e-38 132.6 0.9 1.3e-38 132.6 0.6 2.5 2 1 0 2 2 2 1 Rab-GTPase-TBC domain SMRP1 PF15181.1 XP_011273212.1 - 0.0015 17.9 0.5 0.0025 17.2 0.3 1.2 1 0 0 1 1 1 1 Spermatid-specific manchette-related protein 1 DUF605 PF04652.11 XP_011273212.1 - 8.5 5.6 15.0 13 5.0 10.4 1.2 1 0 0 1 1 1 0 Vta1 like PalH PF08733.5 XP_011273213.1 - 8.3e-94 314.2 13.0 8.3e-94 314.2 9.0 1.5 2 0 0 2 2 2 1 PalH/RIM21 DUF2457 PF10446.4 XP_011273213.1 - 0.037 12.7 9.6 0.052 12.2 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Sec7_N PF12783.2 XP_011273214.1 - 2.1e-36 124.8 5.6 2.1e-36 124.8 3.9 5.1 5 1 0 5 5 5 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Chitin_synth_2 PF03142.10 XP_011273215.1 - 2.3e-283 940.3 0.1 3.2e-283 939.9 0.1 1.2 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 XP_011273215.1 - 1.9e-17 63.6 0.1 4.9e-17 62.2 0.1 1.8 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 XP_011273215.1 - 1.2e-16 61.1 0.0 3.8e-14 53.0 0.0 2.3 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 XP_011273215.1 - 3.3e-05 23.2 0.1 0.00026 20.3 0.0 2.3 3 0 0 3 3 3 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 XP_011273215.1 - 4.8e-05 23.0 0.0 0.0033 17.1 0.0 2.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 Cyt-b5 PF00173.23 XP_011273215.1 - 5.1e-05 22.9 0.1 0.12 12.2 0.1 2.6 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain CTP_transf_1 PF01148.15 XP_011273217.1 - 1.3e-78 264.2 26.0 1.6e-78 263.9 18.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family PAP1 PF08601.5 XP_011273218.1 - 3e-46 158.7 23.9 3.2e-40 138.8 3.1 3.9 1 1 3 4 4 4 2 Transcription factor PAP1 bZIP_1 PF00170.16 XP_011273218.1 - 1.4e-07 31.3 10.5 3e-07 30.2 7.3 1.6 1 0 0 1 1 1 1 bZIP transcription factor DUF4140 PF13600.1 XP_011273218.1 - 0.36 11.2 3.7 1 9.8 2.6 1.8 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) UPF0242 PF06785.6 XP_011273218.1 - 0.78 8.3 3.6 1.3 7.6 2.5 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) bZIP_Maf PF03131.12 XP_011273218.1 - 1.8 8.8 12.1 0.38 11.0 5.3 2.1 2 0 0 2 2 2 0 bZIP Maf transcription factor bZIP_2 PF07716.10 XP_011273218.1 - 5.5 6.8 19.5 0.22 11.3 9.1 2.0 2 1 0 2 2 2 0 Basic region leucine zipper ALS_ss_C PF10369.4 XP_011273219.1 - 1.2e-19 69.8 0.1 4.2e-19 68.0 0.0 1.9 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.20 XP_011273219.1 - 6.4e-11 41.4 0.1 1.2e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 XP_011273219.1 - 9.3e-07 28.5 0.0 1.6e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 ACT domain polyprenyl_synt PF00348.12 XP_011273220.1 - 5.4e-55 186.0 0.0 6.3e-55 185.8 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase NAD_binding_7 PF13241.1 XP_011273224.1 - 1.3e-27 96.0 0.0 2.1e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 XP_011273224.1 - 2.9e-13 48.9 0.0 6e-13 47.9 0.0 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 XP_011273224.1 - 3.3e-13 48.3 0.1 5.3e-13 47.6 0.0 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Shikimate_DH PF01488.15 XP_011273224.1 - 0.0034 17.4 0.0 0.0061 16.6 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.1 XP_011273224.1 - 0.0052 16.8 0.0 0.017 15.1 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 XP_011273224.1 - 0.12 11.2 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase RRM_1 PF00076.17 XP_011273225.1 - 4e-44 148.0 0.0 2.7e-17 62.1 0.0 3.5 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 XP_011273225.1 - 2.9e-30 104.0 0.0 9e-12 44.8 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 XP_011273225.1 - 1.8e-23 82.1 0.0 3.6e-10 39.5 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 XP_011273225.1 - 0.00034 20.3 0.0 0.0018 17.9 0.0 2.2 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 XP_011273225.1 - 0.00034 20.4 0.0 0.0018 18.1 0.0 2.1 2 0 0 2 2 2 1 RNA binding motif Limkain-b1 PF11608.3 XP_011273225.1 - 0.11 12.2 0.0 20 5.0 0.0 2.4 2 0 0 2 2 2 0 Limkain b1 Snf7 PF03357.16 XP_011273226.1 - 6.5e-31 107.0 25.8 6.5e-31 107.0 17.9 1.8 1 1 0 1 1 1 1 Snf7 ALAD PF00490.16 XP_011273227.1 - 1.2e-110 369.4 0.0 1.5e-110 369.1 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase PITH PF06201.8 XP_011273228.1 - 5.3e-43 146.4 5.9 6.5e-43 146.1 4.1 1.1 1 0 0 1 1 1 1 PITH domain Amidase PF01425.16 XP_011273229.1 - 6.3e-74 249.3 0.0 8.4e-74 248.9 0.0 1.2 1 0 0 1 1 1 1 Amidase UPF0180 PF03698.8 XP_011273229.1 - 0.0084 15.9 0.3 0.37 10.6 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0180) SHMT PF00464.14 XP_011273230.1 - 2.5e-209 694.6 0.0 2.9e-209 694.3 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_5 PF00266.14 XP_011273230.1 - 1e-06 27.7 0.0 1.5e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 XP_011273230.1 - 1.1e-05 24.5 0.0 2.3e-05 23.5 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 XP_011273230.1 - 0.00079 18.6 0.0 0.0014 17.8 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Coat_F PF07875.7 XP_011273230.1 - 0.08 13.0 0.2 0.45 10.6 0.1 2.2 2 0 0 2 2 2 0 Coat F domain Aminotran_5 PF00266.14 XP_011273231.1 - 2.3e-27 95.6 0.0 3.2e-27 95.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V DnaJ PF00226.26 XP_011273232.1 - 4.5e-19 67.9 3.4 4.5e-19 67.9 2.3 2.2 2 0 0 2 2 2 1 DnaJ domain YqzH PF14164.1 XP_011273232.1 - 1.3 8.9 5.1 4.9 7.1 0.2 3.1 2 0 0 2 2 2 0 YqzH-like protein DUF814 PF05670.8 XP_011273233.1 - 7.8e-22 76.9 0.0 1.5e-21 76.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF814) TelA PF05816.6 XP_011273233.1 - 0.13 10.9 10.8 0.2 10.3 7.5 1.2 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) COX6B PF02297.12 XP_011273234.1 - 3.5e-19 68.5 6.4 4e-19 68.4 4.4 1.0 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb APOBEC_C PF05240.9 XP_011273234.1 - 0.033 13.5 1.1 0.049 13.0 0.8 1.3 1 0 0 1 1 1 0 APOBEC-like C-terminal domain CHCH PF06747.8 XP_011273234.1 - 0.041 13.8 0.7 0.081 12.8 0.5 1.5 1 1 0 1 1 1 0 CHCH domain ketoacyl-synt PF00109.21 XP_011273234.1 - 0.1 12.0 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain UCR_hinge PF02320.11 XP_011273234.1 - 0.12 12.3 1.1 0.19 11.7 0.7 1.4 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein UPF0203 PF05254.7 XP_011273234.1 - 0.22 11.3 5.3 0.55 10.1 0.9 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) MobB PF03205.9 XP_011273235.1 - 3.3e-06 26.8 0.0 6.7e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 XP_011273235.1 - 0.00012 21.9 0.6 0.0041 17.0 0.0 2.9 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.18 XP_011273235.1 - 0.00023 21.1 0.1 0.0012 18.7 0.1 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arch_ATPase PF01637.13 XP_011273235.1 - 0.00047 19.9 1.2 0.0096 15.6 0.0 2.5 2 0 0 2 2 2 1 Archaeal ATPase FtsK_SpoIIIE PF01580.13 XP_011273235.1 - 0.0011 18.5 0.0 0.0018 17.7 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family Clp1 PF06807.9 XP_011273235.1 - 0.0032 17.2 0.0 0.0099 15.6 0.0 1.8 2 0 0 2 2 2 1 Pre-mRNA cleavage complex II protein Clp1 Miro PF08477.8 XP_011273235.1 - 0.014 15.8 0.0 0.049 14.1 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein AAA_17 PF13207.1 XP_011273235.1 - 0.029 15.1 0.0 0.2 12.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 XP_011273235.1 - 0.032 14.0 0.2 0.11 12.2 0.1 2.1 1 1 0 1 1 1 0 Dynamin family AAA_29 PF13555.1 XP_011273235.1 - 0.033 13.6 0.1 0.081 12.4 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Arf PF00025.16 XP_011273235.1 - 0.048 12.8 0.1 0.11 11.7 0.1 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family ABC_tran PF00005.22 XP_011273235.1 - 0.067 13.4 0.0 0.2 11.9 0.0 1.9 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 XP_011273235.1 - 0.12 12.3 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.1 XP_011273235.1 - 0.23 11.3 0.0 0.61 10.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 XP_011273236.1 - 4.7e-95 314.7 0.0 2.2e-47 160.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 XP_011273236.1 - 2.9e-14 52.6 0.0 1.5e-07 30.7 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 XP_011273236.1 - 2.2e-12 47.2 0.0 0.00013 21.8 0.0 3.3 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 XP_011273236.1 - 7.8e-12 45.5 0.1 0.00011 22.2 0.0 3.7 2 2 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.1 XP_011273236.1 - 2.1e-11 43.8 0.0 5.4e-05 23.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 XP_011273236.1 - 2.5e-11 43.5 0.0 4.2e-05 23.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 XP_011273236.1 - 4e-11 43.1 0.1 0.0088 16.1 0.0 4.8 3 2 1 4 4 3 2 AAA domain AAA_17 PF13207.1 XP_011273236.1 - 5e-11 43.4 3.9 7.2e-07 30.0 0.0 3.7 3 2 0 3 3 2 2 AAA domain Zeta_toxin PF06414.7 XP_011273236.1 - 2.3e-10 39.9 0.0 0.00063 18.8 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin AAA_5 PF07728.9 XP_011273236.1 - 4.3e-10 39.4 1.1 0.00049 19.8 0.0 4.4 3 2 0 3 3 3 2 AAA domain (dynein-related subfamily) TIP49 PF06068.8 XP_011273236.1 - 2.8e-08 32.9 0.0 0.00079 18.2 0.0 2.4 2 0 0 2 2 2 2 TIP49 C-terminus RNA_helicase PF00910.17 XP_011273236.1 - 8.9e-08 32.2 0.6 0.0065 16.6 0.0 3.1 3 0 0 3 3 2 2 RNA helicase AAA_28 PF13521.1 XP_011273236.1 - 6e-07 29.5 0.0 0.0063 16.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 XP_011273236.1 - 6.4e-07 29.0 2.0 0.0061 16.2 0.3 2.7 2 0 0 2 2 2 2 Part of AAA domain Vps4_C PF09336.5 XP_011273236.1 - 1.1e-06 28.4 0.6 0.00034 20.4 0.1 2.9 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_25 PF13481.1 XP_011273236.1 - 1.2e-06 28.0 3.0 0.25 10.7 0.1 4.4 2 2 1 4 4 4 1 AAA domain Mg_chelatase PF01078.16 XP_011273236.1 - 1.6e-06 27.4 1.7 0.02 14.0 0.1 2.7 3 0 0 3 3 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 XP_011273236.1 - 1.8e-06 27.6 0.0 0.021 14.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Cytidylate_kin2 PF13189.1 XP_011273236.1 - 1.9e-06 27.9 0.0 0.00032 20.6 0.0 2.8 2 0 0 2 2 2 1 Cytidylate kinase-like family SKI PF01202.17 XP_011273236.1 - 3.2e-06 27.1 0.0 0.022 14.6 0.0 3.1 2 0 0 2 2 2 2 Shikimate kinase IstB_IS21 PF01695.12 XP_011273236.1 - 3.9e-06 26.3 1.1 0.057 12.8 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein NACHT PF05729.7 XP_011273236.1 - 4.8e-06 26.3 0.2 0.097 12.3 0.0 3.5 2 2 2 4 4 4 2 NACHT domain ABC_tran PF00005.22 XP_011273236.1 - 5.4e-06 26.7 6.2 0.0075 16.5 0.0 3.6 3 1 0 3 3 2 2 ABC transporter AAA_18 PF13238.1 XP_011273236.1 - 1.5e-05 25.3 0.0 4.4e-05 23.7 0.0 4.4 4 1 1 5 5 3 2 AAA domain Rad17 PF03215.10 XP_011273236.1 - 1.9e-05 23.5 0.0 0.0046 15.7 0.0 2.4 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein Viral_helicase1 PF01443.13 XP_011273236.1 - 3e-05 23.6 0.0 0.25 10.8 0.0 2.7 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.17 XP_011273236.1 - 0.00014 20.8 1.8 0.27 10.0 0.0 3.1 3 0 0 3 3 3 2 NB-ARC domain Arch_ATPase PF01637.13 XP_011273236.1 - 0.00016 21.4 3.7 0.28 10.8 0.0 4.4 3 2 2 5 5 5 1 Archaeal ATPase Sigma54_activat PF00158.21 XP_011273236.1 - 0.0002 20.8 0.0 0.31 10.4 0.0 3.1 2 1 0 2 2 2 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 XP_011273236.1 - 0.00051 20.1 0.0 1.4 9.0 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain NTPase_1 PF03266.10 XP_011273236.1 - 0.00072 19.2 0.0 1.3 8.7 0.0 3.3 3 0 0 3 3 3 1 NTPase DUF815 PF05673.8 XP_011273236.1 - 0.00075 18.5 0.1 0.19 10.5 0.0 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF815) KaiC PF06745.8 XP_011273236.1 - 0.00083 18.5 0.3 2.5 7.1 0.0 3.1 3 0 0 3 3 3 2 KaiC ATP-synt_ab PF00006.20 XP_011273236.1 - 0.0018 17.8 0.0 2 7.8 0.0 2.6 3 0 0 3 3 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_24 PF13479.1 XP_011273236.1 - 0.0022 17.6 0.1 3.1 7.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain PhoH PF02562.11 XP_011273236.1 - 0.0026 17.0 0.3 1.1 8.4 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein Parvo_NS1 PF01057.12 XP_011273236.1 - 0.0031 16.4 0.3 2.3 6.9 0.0 2.6 3 0 0 3 3 2 2 Parvovirus non-structural protein NS1 CPT PF07931.7 XP_011273236.1 - 0.0039 16.8 0.0 0.033 13.8 0.0 2.2 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein UPF0079 PF02367.12 XP_011273236.1 - 0.015 14.9 0.1 1.7 8.2 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 PduV-EutP PF10662.4 XP_011273236.1 - 0.02 14.3 0.0 5.3 6.5 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 XP_011273236.1 - 0.029 14.3 0.1 2.2 8.2 0.0 3.4 2 2 1 3 3 2 0 50S ribosome-binding GTPase AAA_29 PF13555.1 XP_011273236.1 - 0.036 13.5 0.0 0.88 9.1 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF387 PF04079.11 XP_011273236.1 - 0.045 13.1 0.2 0.1 11.9 0.1 1.6 1 0 0 1 1 1 0 Putative transcriptional regulators (Ypuh-like) Imm2 PF14426.1 XP_011273236.1 - 0.05 13.6 0.2 0.25 11.3 0.1 2.2 1 0 0 1 1 1 0 Immunity protein Imm2 DUF258 PF03193.11 XP_011273236.1 - 0.071 12.2 0.0 0.89 8.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 TPR_11 PF13414.1 XP_011273237.1 - 8.5e-05 22.1 0.6 0.0073 15.9 0.1 2.3 1 1 1 2 2 2 1 TPR repeat TPR_9 PF13371.1 XP_011273237.1 - 0.0015 18.3 0.1 0.015 15.0 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 XP_011273237.1 - 0.016 15.0 0.0 27 5.0 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 XP_011273237.1 - 0.035 13.7 0.1 11 5.8 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Ras PF00071.17 XP_011273238.1 - 2.8e-49 166.6 0.0 3.5e-49 166.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 XP_011273238.1 - 7.6e-15 55.4 0.0 1.5e-14 54.4 0.0 1.5 2 0 0 2 2 1 1 Miro-like protein Arf PF00025.16 XP_011273238.1 - 3.3e-11 42.7 0.0 4.3e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.17 XP_011273238.1 - 0.00026 21.1 0.1 0.002 18.2 0.1 2.1 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.7 XP_011273238.1 - 0.0012 18.0 0.0 0.0017 17.5 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Pox_A32 PF04665.7 XP_011273238.1 - 0.023 14.0 0.1 0.038 13.2 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein SRPRB PF09439.5 XP_011273238.1 - 0.047 12.9 0.0 0.081 12.1 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit G-alpha PF00503.15 XP_011273238.1 - 0.053 12.2 2.2 1.1 7.8 0.1 2.7 2 1 1 3 3 3 0 G-protein alpha subunit AAA_22 PF13401.1 XP_011273238.1 - 0.066 13.3 0.2 0.2 11.7 0.1 1.9 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.1 XP_011273238.1 - 0.069 13.0 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 XP_011273238.1 - 0.11 12.0 0.1 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.1 XP_011273238.1 - 0.12 11.9 0.1 0.23 10.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 XP_011273238.1 - 0.14 11.8 0.1 0.31 10.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 zf-U1 PF06220.7 XP_011273239.1 - 0.0002 20.8 0.2 0.00031 20.2 0.2 1.3 1 0 0 1 1 1 1 U1 zinc finger ATP_sub_h PF10775.4 XP_011273240.1 - 1.5e-25 88.6 0.2 2e-25 88.2 0.2 1.2 1 0 0 1 1 1 1 ATP synthase complex subunit h ADIP PF11559.3 XP_011273241.1 - 7.2e-14 51.9 26.9 7.2e-14 51.9 18.6 2.9 3 0 0 3 3 3 1 Afadin- and alpha -actinin-Binding Aldedh PF00171.17 XP_011273242.1 - 1.2e-163 544.7 0.0 1.4e-163 544.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Cellulase PF00150.13 XP_011273243.1 - 2.2e-14 53.3 10.3 9.9e-14 51.2 7.2 1.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Trehalase PF01204.13 XP_011273244.1 - 8.9e-179 595.3 0.2 1.2e-178 594.9 0.2 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 XP_011273244.1 - 1.8e-16 59.1 3.1 3.7e-16 58.1 2.1 1.6 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain Ran_BP1 PF00638.13 XP_011273245.1 - 7.6e-53 177.7 2.4 1.1e-52 177.2 1.7 1.2 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.18 XP_011273245.1 - 2.2e-05 24.1 0.9 0.00025 20.7 0.6 2.1 1 1 0 1 1 1 1 WH1 domain DUF1681 PF07933.9 XP_011273245.1 - 0.0095 15.5 0.3 0.0095 15.5 0.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1681) Cellulose_synt PF03552.9 XP_011273245.1 - 0.015 13.5 1.3 0.023 13.0 0.9 1.2 1 0 0 1 1 1 0 Cellulose synthase CDC27 PF09507.5 XP_011273245.1 - 0.074 12.2 18.5 0.11 11.7 12.8 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CDC45 PF02724.9 XP_011273245.1 - 0.23 9.4 4.7 0.23 9.4 3.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Prenyltransf PF01255.14 XP_011273246.1 - 2e-78 262.5 1.1 2.6e-78 262.2 0.8 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase polyprenyl_synt PF00348.12 XP_011273247.1 - 4.8e-51 173.1 0.5 4.1e-24 84.8 0.1 3.1 2 1 1 3 3 3 3 Polyprenyl synthetase HEPPP_synt_1 PF07307.6 XP_011273247.1 - 0.067 12.6 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Sugar_tr PF00083.19 XP_011273248.1 - 3.7e-130 434.5 28.7 4.5e-130 434.2 19.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 XP_011273248.1 - 4.1e-32 111.2 28.5 1.1e-28 100.0 17.9 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 XP_011273248.1 - 1e-07 30.5 5.7 1e-07 30.5 3.9 1.9 1 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DER1 PF04511.10 XP_011273250.1 - 5.1e-37 127.2 7.6 6e-37 127.0 5.2 1.1 1 0 0 1 1 1 1 Der1-like family DUF1751 PF08551.5 XP_011273250.1 - 0.0077 16.5 2.5 0.033 14.5 0.3 2.2 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) DUF4113 PF13438.1 XP_011273251.1 - 0.058 13.0 0.2 0.096 12.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4113) Lge1 PF11488.3 XP_011273251.1 - 0.15 12.2 1.4 0.28 11.3 0.2 2.1 2 1 0 2 2 2 0 Transcriptional regulatory protein LGE1 Pirin PF02678.11 XP_011273252.1 - 9.4e-29 99.4 0.1 1.7e-28 98.5 0.0 1.4 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.8 XP_011273252.1 - 8.4e-22 77.2 0.1 3.2e-21 75.3 0.1 1.9 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 XP_011273252.1 - 9.9e-05 21.7 0.8 0.0071 15.8 0.3 2.3 2 0 0 2 2 2 2 Cupin domain Aldedh PF00171.17 XP_011273253.1 - 1.1e-175 584.3 0.0 1.4e-175 584.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 XP_011273253.1 - 0.001 17.9 0.0 0.0022 16.7 0.0 1.6 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) NUDIX PF00293.23 XP_011273254.1 - 1.4e-14 53.9 0.0 2.5e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.6 XP_011273254.1 - 0.00013 22.2 0.0 0.00023 21.4 0.0 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.6 XP_011273254.1 - 0.012 15.1 0.4 0.019 14.4 0.3 1.3 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain Herpes_capsid PF06112.6 XP_011273255.1 - 0.091 12.7 11.3 0.84 9.6 0.5 2.5 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein F-box-like PF12937.2 XP_011273256.1 - 0.049 13.3 1.0 0.11 12.2 0.7 1.7 1 0 0 1 1 1 0 F-box-like F-box PF00646.28 XP_011273256.1 - 0.1 12.2 3.4 0.094 12.4 0.2 2.3 2 0 0 2 2 2 0 F-box domain TFIIA PF03153.8 XP_011273257.1 - 0.036 13.9 11.2 0.068 13.0 7.7 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit F-box PF00646.28 XP_011273257.1 - 0.043 13.4 0.5 0.11 12.1 0.3 1.7 1 0 0 1 1 1 0 F-box domain NOA36 PF06524.7 XP_011273257.1 - 0.056 12.7 16.3 0.087 12.0 11.3 1.2 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.9 XP_011273257.1 - 0.23 9.4 10.5 0.39 8.6 7.3 1.3 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 XP_011273257.1 - 0.37 9.2 16.7 0.57 8.5 11.6 1.2 1 0 0 1 1 1 0 Daxx Family VID27 PF08553.5 XP_011273257.1 - 0.37 8.9 14.5 0.56 8.3 10.1 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein Nop14 PF04147.7 XP_011273257.1 - 0.68 7.7 19.6 1.2 7.0 13.6 1.3 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.7 XP_011273257.1 - 2.1 7.3 16.9 3.8 6.5 11.7 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CENP-B_dimeris PF09026.5 XP_011273257.1 - 4.1 7.7 26.3 10 6.4 18.2 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Sigma70_ner PF04546.8 XP_011273257.1 - 8 6.0 15.4 18 4.8 10.7 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region NDUFB10 PF10249.4 XP_011273258.1 - 0.029 14.5 0.4 0.044 13.9 0.3 1.3 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit 10 CD45 PF12567.3 XP_011273259.1 - 0.048 13.5 1.6 0.048 13.5 1.1 1.7 1 1 0 1 1 1 0 Leukocyte receptor CD45 DUF3112 PF11309.3 XP_011273260.1 - 8.5e-41 139.4 12.0 8.5e-41 139.4 8.3 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3112) DUF2614 PF11023.3 XP_011273261.1 - 0.79 9.5 10.2 3.1 7.6 0.4 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF2614) Tcp11 PF05794.8 XP_011273263.1 - 3e-130 434.8 13.5 3e-130 434.8 9.4 1.6 2 0 0 2 2 2 1 T-complex protein 11 Yippee-Mis18 PF03226.9 XP_011273263.1 - 0.41 10.7 3.9 0.54 10.3 0.2 2.7 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly MFS_1 PF07690.11 XP_011273264.1 - 8.4e-32 110.2 36.9 1.2e-29 103.1 24.9 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 XP_011273264.1 - 0.00022 19.5 4.9 0.00039 18.6 3.4 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector IncA PF04156.9 XP_011273264.1 - 0.0069 16.0 2.0 0.0069 16.0 1.4 3.2 3 1 0 3 3 3 1 IncA protein DUF3493 PF11998.3 XP_011273264.1 - 0.91 9.4 0.0 0.91 9.4 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3493) MFS_1 PF07690.11 XP_011273265.1 - 4.3e-32 111.2 24.7 4.3e-32 111.2 17.1 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 XP_011273265.1 - 6.8e-05 21.4 34.2 0.00019 19.9 7.9 2.7 2 1 1 3 3 3 2 MFS/sugar transport protein Lysis_S PF04971.7 XP_011273265.1 - 0.2 11.3 2.6 0.76 9.5 1.0 2.6 2 0 0 2 2 2 0 Lysis protein S DUF3792 PF12670.2 XP_011273265.1 - 0.39 10.5 0.1 0.39 10.5 0.0 4.7 5 1 0 5 5 5 0 Protein of unknown function (DUF3792) ERGIC_N PF13850.1 XP_011273265.1 - 0.54 10.2 5.8 15 5.6 0.1 3.4 2 1 1 3 3 3 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Pkinase PF00069.20 XP_011273266.1 - 1e-64 218.2 0.2 1.4e-64 217.7 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011273266.1 - 6.5e-33 113.9 0.0 9.9e-33 113.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 XP_011273266.1 - 1.4e-05 24.1 0.0 2.5e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 XP_011273266.1 - 0.033 13.9 0.0 0.054 13.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Macro PF01661.16 XP_011273267.1 - 1.3e-22 79.9 0.0 1.6e-22 79.6 0.0 1.1 1 0 0 1 1 1 1 Macro domain Rep_fac_C PF08542.6 XP_011273268.1 - 3.7e-17 62.0 0.1 1e-16 60.6 0.1 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 XP_011273268.1 - 5.5e-13 48.8 4.7 1.3e-12 47.7 0.1 2.3 1 1 1 2 2 2 1 DNA polymerase III, delta subunit DNA_pol3_delta PF06144.8 XP_011273268.1 - 3.7e-07 29.8 1.9 7e-07 28.9 1.3 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 XP_011273268.1 - 4.8e-07 30.0 0.1 9e-07 29.1 0.1 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 XP_011273268.1 - 0.016 15.3 0.1 0.051 13.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain DEAD PF00270.24 XP_011273268.1 - 0.018 14.5 0.0 0.042 13.3 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_14 PF13173.1 XP_011273268.1 - 0.028 14.3 0.3 0.086 12.7 0.1 1.8 1 1 1 2 2 2 0 AAA domain DUF3130 PF11328.3 XP_011273268.1 - 0.038 14.0 0.1 0.51 10.4 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3130 DUF2877 PF11392.3 XP_011273268.1 - 0.081 13.1 0.2 0.59 10.3 0.0 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2877) RQC PF09382.5 XP_011273269.1 - 1.8e-24 85.4 0.2 5.3e-24 83.9 0.2 1.9 1 0 0 1 1 1 1 RQC domain Helicase_C PF00271.26 XP_011273269.1 - 2.7e-21 75.1 0.2 5.4e-19 67.8 0.0 3.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.24 XP_011273269.1 - 7.2e-20 71.1 0.0 1.9e-19 69.7 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_Sgs1 PF11408.3 XP_011273269.1 - 6.1e-09 35.5 0.8 2.5e-08 33.6 0.5 2.1 1 0 0 1 1 1 1 Sgs1 RecQ helicase HRDC PF00570.18 XP_011273269.1 - 2.7e-06 27.0 0.3 9e-06 25.3 0.0 2.0 2 0 0 2 2 2 1 HRDC domain UQ_con PF00179.21 XP_011273270.1 - 1.1e-21 76.7 0.4 1.5e-21 76.3 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 XP_011273270.1 - 7.4e-07 28.9 0.0 1.6e-06 27.8 0.0 1.4 1 1 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 XP_011273270.1 - 1.2e-05 25.0 0.1 1.4e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 UEV domain RWD PF05773.17 XP_011273270.1 - 0.023 14.6 0.7 0.042 13.7 0.5 1.6 1 1 0 1 1 1 0 RWD domain Tn7_Tnp_TnsA_C PF08721.6 XP_011273270.1 - 0.075 13.0 0.2 0.2 11.6 0.0 1.9 2 0 0 2 2 2 0 TnsA endonuclease C terminal WD40 PF00400.27 XP_011273271.1 - 6.8e-20 70.1 3.2 7.6e-09 35.1 0.0 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat GDC-P PF02347.11 XP_011273272.1 - 6.1e-190 631.4 0.0 3.9e-180 599.1 0.0 2.9 3 0 0 3 3 3 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 XP_011273272.1 - 0.00019 20.6 0.0 0.00039 19.6 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase Mid1 PF12929.2 XP_011273273.1 - 4.7e-121 404.4 10.2 7.2e-121 403.8 7.0 1.2 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.17 XP_011273273.1 - 0.56 10.5 4.6 1.3 9.4 0.2 2.8 3 0 0 3 3 3 0 Fz domain Fungal_trans PF04082.13 XP_011273274.1 - 8.4e-34 116.6 2.6 1.9e-33 115.4 1.8 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Gal4_dimer PF03902.8 XP_011273274.1 - 3.1e-11 43.0 0.2 6.1e-11 42.0 0.1 1.5 1 0 0 1 1 1 1 Gal4-like dimerisation domain PulS_OutS PF09691.5 XP_011273274.1 - 0.0087 16.0 0.1 0.022 14.7 0.0 1.7 1 0 0 1 1 1 1 Bacterial chaperone lipoprotein (PulS_OutS) FlaC_arch PF05377.6 XP_011273275.1 - 0.031 14.1 2.6 0.053 13.4 0.3 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) RabGAP-TBC PF00566.13 XP_011273276.1 - 7.1e-47 159.6 3.9 7.1e-47 159.6 2.7 4.2 4 1 0 4 4 4 1 Rab-GTPase-TBC domain Ribosomal_L28 PF00830.14 XP_011273277.1 - 4.6e-19 67.9 2.4 1.1e-18 66.7 0.6 2.1 2 0 0 2 2 2 1 Ribosomal L28 family CysG_dimeriser PF10414.4 XP_011273277.1 - 0.058 12.8 2.2 0.12 11.9 1.5 1.4 1 0 0 1 1 1 0 Sirohaem synthase dimerisation region Mmp37 PF09139.6 XP_011273278.1 - 9.3e-98 327.2 13.1 1.2e-89 300.6 2.9 2.3 2 1 0 3 3 3 2 Mitochondrial matrix Mmp37 Sen15 PF09631.5 XP_011273279.1 - 4.5e-26 91.0 0.2 5e-26 90.8 0.2 1.0 1 0 0 1 1 1 1 Sen15 protein Tom37_C PF11801.3 XP_011273280.1 - 8.2e-32 110.3 3.3 1.1e-31 109.9 2.3 1.2 1 0 0 1 1 1 1 Tom37 C-terminal domain Tom37 PF10568.4 XP_011273280.1 - 3.8e-21 75.1 0.2 6.6e-21 74.3 0.2 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_N_2 PF13409.1 XP_011273280.1 - 0.063 13.2 0.0 0.2 11.7 0.0 1.9 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain LRR_4 PF12799.2 XP_011273282.1 - 0.14 11.7 2.4 0.45 10.1 0.1 2.8 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) F-box-like PF12937.2 XP_011273283.1 - 2.9e-05 23.6 0.2 0.0043 16.7 0.2 2.5 2 0 0 2 2 2 2 F-box-like F-box PF00646.28 XP_011273283.1 - 0.0026 17.3 2.4 0.024 14.2 0.3 2.7 2 0 0 2 2 2 1 F-box domain PRANC PF09372.5 XP_011273283.1 - 0.3 11.0 7.4 9.3 6.2 0.4 4.0 3 2 1 4 4 4 0 PRANC domain MFS_1 PF07690.11 XP_011273284.1 - 2.5e-40 138.3 65.7 6.6e-32 110.5 24.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 XP_011273284.1 - 2.1e-13 49.7 28.6 1.3e-09 37.2 2.7 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter Transglut_core PF01841.14 XP_011273284.1 - 0.046 13.9 0.0 0.085 13.0 0.0 1.4 1 0 0 1 1 1 0 Transglutaminase-like superfamily Stb3 PF10330.4 XP_011273284.1 - 0.18 11.5 0.0 0.42 10.3 0.0 1.6 1 0 0 1 1 1 0 Putative Sin3 binding protein MFS_1 PF07690.11 XP_011273285.1 - 3.2e-32 111.6 31.3 3.2e-32 111.6 21.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 XP_011273285.1 - 0.018 14.8 2.4 0.048 13.4 0.0 2.9 3 0 0 3 3 3 0 MFS_1 like family DUF4131 PF13567.1 XP_011273285.1 - 8.6 5.7 14.2 2.8 7.3 0.0 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4131) TauD PF02668.11 XP_011273287.1 - 6.1e-25 88.3 0.0 8.3e-25 87.9 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF3053 PF11254.3 XP_011273287.1 - 0.13 11.5 0.0 0.24 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3053) MFS_1 PF07690.11 XP_011273288.1 - 5.5e-29 100.9 20.5 5.5e-29 100.9 14.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Cornichon PF03311.9 XP_011273288.1 - 0.06 13.4 0.1 0.06 13.4 0.0 3.3 4 0 0 4 4 4 0 Cornichon protein LigB PF02900.13 XP_011273289.1 - 1.5e-23 83.1 0.0 1.8e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase DUF1139 PF06599.6 XP_011273289.1 - 0.75 8.9 4.6 0.08 12.0 0.3 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1139) MFS_1 PF07690.11 XP_011273290.1 - 2.6e-27 95.4 16.1 3.9e-27 94.9 11.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily QueT PF06177.6 XP_011273290.1 - 1.9 8.4 8.3 0.28 11.1 1.5 2.6 2 1 0 2 2 2 0 QueT transporter Cyclin_N PF00134.18 XP_011273291.1 - 1.3e-40 137.8 2.9 5e-40 135.9 1.4 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 XP_011273291.1 - 9.6e-08 31.9 2.9 2.7e-07 30.5 0.6 2.8 2 1 0 2 2 2 1 Cyclin, C-terminal domain Sad1_UNC PF07738.8 XP_011273292.1 - 1.4e-33 115.5 3.2 2.4e-33 114.8 0.2 2.5 2 0 0 2 2 2 1 Sad1 / UNC-like C-terminal ATP-synt_ab PF00006.20 XP_011273293.1 - 1.2e-62 211.2 0.0 1.7e-62 210.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 XP_011273293.1 - 8.1e-26 90.7 0.3 1.3e-25 90.0 0.2 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 XP_011273293.1 - 1.4e-22 79.6 1.6 1.9e-22 79.2 0.2 2.0 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain AAA_25 PF13481.1 XP_011273293.1 - 0.002 17.5 0.0 0.0062 15.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 XP_011273293.1 - 0.0023 17.0 0.2 0.0038 16.3 0.1 1.4 1 0 0 1 1 1 1 KaiC MobB PF03205.9 XP_011273293.1 - 0.0092 15.6 0.1 0.58 9.8 0.0 2.9 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 XP_011273293.1 - 0.013 14.4 0.8 0.52 9.1 0.1 2.3 2 0 0 2 2 2 0 NB-ARC domain NACHT PF05729.7 XP_011273293.1 - 0.026 14.1 0.2 0.076 12.6 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.1 XP_011273293.1 - 0.042 13.8 0.2 0.24 11.3 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain DUF258 PF03193.11 XP_011273293.1 - 0.048 12.8 0.1 0.086 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 XP_011273293.1 - 0.09 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.1 XP_011273293.1 - 0.12 12.5 0.0 0.46 10.6 0.0 2.0 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 XP_011273293.1 - 0.15 11.7 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase P5CR_dimer PF14748.1 XP_011273294.1 - 2e-32 111.3 0.1 3.4e-32 110.6 0.1 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 XP_011273294.1 - 7.9e-17 61.4 0.0 1.8e-16 60.3 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 XP_011273294.1 - 9.4e-05 21.8 0.0 0.00017 21.0 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 XP_011273294.1 - 0.0004 20.1 0.0 0.00082 19.1 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Saccharop_dh PF03435.13 XP_011273294.1 - 0.042 12.8 0.0 0.068 12.1 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 XP_011273294.1 - 0.11 12.7 0.0 0.24 11.7 0.0 1.7 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 XP_011273294.1 - 0.12 12.9 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold JmjC PF02373.17 XP_011273295.1 - 2.3e-36 124.5 0.5 4.8e-36 123.4 0.3 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.12 XP_011273295.1 - 7.3e-12 44.5 0.1 1.5e-11 43.6 0.1 1.6 1 0 0 1 1 1 1 jmjN domain PHD PF00628.24 XP_011273295.1 - 2.5e-11 43.0 6.4 2.5e-11 43.0 4.4 2.3 2 0 0 2 2 2 1 PHD-finger Prok-RING_1 PF14446.1 XP_011273295.1 - 0.0019 17.8 5.7 0.0027 17.4 1.6 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 PHD_2 PF13831.1 XP_011273295.1 - 0.24 10.7 5.6 0.081 12.2 1.1 2.2 2 0 0 2 2 2 0 PHD-finger Aldo_ket_red PF00248.16 XP_011273296.1 - 8.2e-43 146.2 0.0 1e-42 145.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Ilm1 PF10311.4 XP_011273296.1 - 1.2e-05 24.8 1.2 2.3e-05 23.9 0.2 2.0 2 0 0 2 2 2 1 Increased loss of mitochondrial DNA protein 1 Ilm1 PF10311.4 XP_011273297.1 - 1.1e-38 132.3 7.1 2.5e-38 131.1 4.9 1.5 1 1 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 Retrotrans_gag PF03732.12 XP_011273297.1 - 0.14 12.2 0.5 0.21 11.6 0.4 1.3 1 0 0 1 1 1 0 Retrotransposon gag protein Glyco_transf_34 PF05637.7 XP_011273298.1 - 1e-52 179.0 2.5 1.3e-52 178.6 1.7 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Sec5 PF15469.1 XP_011273298.1 - 0.023 14.4 0.5 0.052 13.2 0.3 1.6 1 0 0 1 1 1 0 Exocyst complex component Sec5 Sec1 PF00995.18 XP_011273299.1 - 1.3e-59 202.3 28.6 1.6e-59 202.0 19.9 1.1 1 0 0 1 1 1 1 Sec1 family Pkinase PF00069.20 XP_011273300.1 - 0.0029 16.7 1.7 0.0043 16.2 0.4 1.9 2 1 0 2 2 2 1 Protein kinase domain COX7C PF02935.11 XP_011273301.1 - 1.4e-22 79.1 2.6 1.7e-22 79.0 1.8 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Ureidogly_hydro PF04115.7 XP_011273301.1 - 0.048 12.9 0.1 0.055 12.8 0.1 1.1 1 0 0 1 1 1 0 Ureidoglycolate hydrolase Pol_alpha_B_N PF08418.5 XP_011273302.1 - 8.4e-54 182.7 4.6 1.6e-53 181.8 3.2 1.5 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.11 XP_011273302.1 - 1.5e-40 138.7 1.2 3.1e-40 137.6 0.9 1.6 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Hep_59 PF07052.6 XP_011273302.1 - 0.044 14.1 0.1 0.1 12.9 0.1 1.6 1 0 0 1 1 1 0 Hepatocellular carcinoma-associated antigen 59 Anoctamin PF04547.7 XP_011273303.1 - 1.7e-103 346.7 15.4 1.7e-103 346.7 10.7 2.0 2 0 0 2 2 2 1 Calcium-activated chloride channel Ala_racemase_N PF01168.15 XP_011273304.1 - 2.7e-41 141.5 0.0 3.3e-41 141.2 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Adaptin_N PF01602.15 XP_011273305.1 - 4e-89 299.3 22.2 5.2e-89 298.9 15.4 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 XP_011273305.1 - 1.2e-07 32.0 0.5 3.2e-07 30.6 0.4 1.8 1 0 0 1 1 1 1 Adaptin C-terminal domain Alpha_adaptin_C PF02296.11 XP_011273305.1 - 4.9e-06 26.4 0.0 1.1e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain HEAT_2 PF13646.1 XP_011273305.1 - 0.0028 17.8 0.1 0.95 9.7 0.0 3.5 3 1 0 3 3 3 1 HEAT repeats DUF92 PF01940.11 XP_011273306.1 - 7.4e-63 211.7 4.6 1e-62 211.2 3.2 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 Frag1 PF10277.4 XP_011273306.1 - 0.00018 21.0 0.3 0.00078 18.9 0.1 2.1 1 1 1 2 2 2 1 Frag1/DRAM/Sfk1 family CoA_binding_3 PF13727.1 XP_011273306.1 - 0.099 12.4 0.1 14 5.4 0.0 2.4 2 0 0 2 2 2 0 CoA-binding domain DUF1673 PF07895.6 XP_011273306.1 - 6.2 6.2 8.4 0.49 9.8 0.6 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1673) Peptidase_M16_C PF05193.16 XP_011273307.1 - 4.4e-19 68.8 0.3 3.7e-13 49.5 0.0 3.8 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 XP_011273307.1 - 4.1e-11 42.8 0.1 1.6e-08 34.4 0.0 2.7 2 0 0 2 2 2 2 Insulinase (Peptidase family M16) M16C_assoc PF08367.6 XP_011273307.1 - 0.0046 15.8 0.3 0.0046 15.8 0.2 4.5 5 1 1 6 6 6 2 Peptidase M16C associated CDC45 PF02724.9 XP_011273307.1 - 0.35 8.8 10.3 0.52 8.2 7.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Pro_isomerase PF00160.16 XP_011273308.1 - 1.3e-39 135.8 1.4 1.8e-39 135.4 0.9 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Cas_VVA1548 PF09652.5 XP_011273308.1 - 0.084 12.8 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Putative CRISPR-associated protein (Cas_VVA1548) OAD_gamma PF04277.8 XP_011273308.1 - 0.2 12.0 1.6 1.2 9.5 0.0 2.4 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain cobW PF02492.14 XP_011273309.1 - 1.5e-40 138.5 0.1 2.4e-40 137.8 0.0 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 XP_011273309.1 - 6.6e-11 41.7 0.0 1.4e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain GTP_EFTU PF00009.22 XP_011273309.1 - 0.0002 20.8 0.3 0.47 9.8 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 XP_011273309.1 - 0.00027 20.4 0.0 0.00077 18.9 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.1 XP_011273309.1 - 0.00087 19.5 0.2 0.00087 19.5 0.2 2.9 3 2 0 3 3 3 1 AAA domain ATP_bind_1 PF03029.12 XP_011273309.1 - 0.004 16.7 0.1 0.0086 15.6 0.1 1.5 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein DAP3 PF10236.4 XP_011273309.1 - 0.0052 15.7 0.0 0.0083 15.0 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.1 XP_011273309.1 - 0.0078 16.2 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.18 XP_011273309.1 - 0.01 15.8 0.0 0.031 14.2 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_17 PF13207.1 XP_011273309.1 - 0.011 16.5 0.2 0.13 13.1 0.0 2.5 2 2 0 2 2 2 0 AAA domain AAA_23 PF13476.1 XP_011273309.1 - 0.018 15.3 2.8 0.018 15.3 2.0 2.8 2 1 1 3 3 3 0 AAA domain AAA_14 PF13173.1 XP_011273309.1 - 0.023 14.5 0.3 0.085 12.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 XP_011273309.1 - 0.024 14.7 0.1 0.11 12.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 XP_011273309.1 - 0.04 13.6 0.3 0.22 11.2 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 XP_011273309.1 - 0.046 12.9 0.3 0.12 11.5 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_33 PF13671.1 XP_011273309.1 - 0.052 13.4 0.0 0.086 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 XP_011273309.1 - 0.059 13.0 0.1 0.4 10.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ArgK PF03308.11 XP_011273309.1 - 0.061 12.0 0.7 0.63 8.7 0.0 2.4 3 0 0 3 3 3 0 ArgK protein NACHT PF05729.7 XP_011273309.1 - 0.12 12.0 0.5 0.23 11.0 0.4 1.4 1 0 0 1 1 1 0 NACHT domain Glyco_transf_22 PF03901.12 XP_011273310.1 - 7.4e-37 127.3 14.4 9.7e-37 126.9 10.0 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Img2 PF05046.9 XP_011273311.1 - 1.4e-19 70.0 0.6 1.9e-19 69.6 0.1 1.4 2 0 0 2 2 2 1 Mitochondrial large subunit ribosomal protein (Img2) WD40 PF00400.27 XP_011273312.1 - 4.8e-87 283.0 31.3 9.5e-16 57.0 0.1 8.3 8 0 0 8 8 8 8 WD domain, G-beta repeat NLE PF08154.7 XP_011273312.1 - 7.5e-11 41.8 0.1 1.3e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain eIF2A PF08662.6 XP_011273312.1 - 2.2e-08 34.0 3.1 0.0052 16.5 0.0 3.6 2 2 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 XP_011273312.1 - 2.6e-07 29.1 6.6 0.0086 14.2 0.1 4.4 3 2 2 5 5 5 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 XP_011273312.1 - 0.011 14.1 0.3 0.022 13.0 0.0 1.7 2 0 0 2 2 2 0 Cytochrome D1 heme domain Nbas_N PF15492.1 XP_011273312.1 - 0.029 13.4 2.0 2.4 7.2 0.1 3.1 3 1 0 4 4 4 0 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.7 XP_011273312.1 - 0.052 13.2 1.0 3.9 7.2 0.0 3.1 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Pkinase PF00069.20 XP_011273313.1 - 5.5e-69 232.2 0.0 1.1e-68 231.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011273313.1 - 1.5e-40 138.9 0.0 2.4e-40 138.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 XP_011273313.1 - 9e-09 34.7 0.0 1.8e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 XP_011273313.1 - 0.0034 17.1 0.0 0.0076 16.0 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 XP_011273313.1 - 0.0051 16.1 0.2 0.014 14.7 0.1 1.7 1 0 0 1 1 1 1 RIO1 family DUF1626 PF07788.6 XP_011273313.1 - 0.058 13.1 0.2 0.18 11.6 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1626) UCR_hinge PF02320.11 XP_011273314.1 - 1e-20 73.4 6.6 1e-20 73.4 4.6 2.4 2 1 0 2 2 2 1 Ubiquinol-cytochrome C reductase hinge protein MIP-T3 PF10243.4 XP_011273314.1 - 0.00043 18.8 56.2 0.00051 18.6 39.0 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Mitofilin PF09731.4 XP_011273314.1 - 0.67 8.5 40.9 0.83 8.2 28.4 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Ribosomal_L7Ae PF01248.21 XP_011273315.1 - 9.5e-23 79.5 0.4 1.6e-22 78.8 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family FGGY_C PF02782.11 XP_011273316.1 - 8.7e-66 221.3 0.3 3.7e-65 219.2 0.1 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 XP_011273316.1 - 5.2e-52 176.6 2.0 2e-43 148.4 0.2 2.8 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 XP_011273316.1 - 0.0061 15.8 0.2 0.029 13.6 0.0 2.0 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family MIP PF00230.15 XP_011273317.1 - 1.7e-52 178.1 5.6 2.1e-52 177.8 3.9 1.1 1 0 0 1 1 1 1 Major intrinsic protein V-SNARE_C PF12352.3 XP_011273319.1 - 3.1e-08 33.5 1.5 3.1e-08 33.5 1.1 2.3 2 1 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 XP_011273319.1 - 2.7 7.7 8.4 0.8 9.4 0.2 3.0 1 1 2 3 3 3 0 Sec20 Autophagy_act_C PF03987.10 XP_011273320.1 - 1.9e-06 27.9 0.3 4.9e-06 26.6 0.0 1.9 2 0 0 2 2 2 1 Autophagocytosis associated protein, active-site domain Cellulose_synt PF03552.9 XP_011273320.1 - 0.066 11.5 0.1 0.082 11.1 0.0 1.1 1 0 0 1 1 1 0 Cellulose synthase Fer2_3 PF13085.1 XP_011273321.1 - 2.1e-32 111.2 0.1 3.4e-32 110.5 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 XP_011273321.1 - 1.2e-10 41.5 7.3 1.2e-10 41.5 5.1 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 XP_011273321.1 - 2.7e-08 33.6 5.7 2.7e-08 33.6 3.9 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 XP_011273321.1 - 0.00029 21.0 5.4 0.036 14.3 0.4 3.1 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_18 PF13746.1 XP_011273321.1 - 0.00048 20.5 3.0 0.00048 20.5 2.1 2.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 XP_011273321.1 - 0.001 18.8 5.2 0.001 18.8 3.6 2.5 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 XP_011273321.1 - 0.0011 19.3 4.7 0.0011 19.3 3.3 2.5 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 XP_011273321.1 - 0.004 16.8 4.3 0.0066 16.1 0.6 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Imm39 PF15600.1 XP_011273323.1 - 0.15 11.9 6.6 1.8 8.3 0.0 3.0 2 1 0 3 3 3 0 Immunity protein 39 PI-PLC-X PF00388.14 XP_011273324.1 - 1.7e-19 69.6 0.0 2.7e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Copper-fist PF00649.13 XP_011273325.1 - 1.7e-21 75.0 1.0 1.7e-21 75.0 0.7 2.6 1 1 1 2 2 2 2 Copper fist DNA binding domain Ran-binding PF05508.6 XP_011273326.1 - 3.8e-114 380.6 5.3 6.3e-114 379.9 3.7 1.3 1 0 0 1 1 1 1 RanGTP-binding protein DUF1664 PF07889.7 XP_011273326.1 - 0.016 15.0 0.8 0.048 13.4 0.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF592 PF04574.8 XP_011273327.1 - 0.048 13.2 0.0 0.088 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF592) SNF2_N PF00176.18 XP_011273329.1 - 1.5e-68 230.8 0.0 2.5e-68 230.0 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.5 XP_011273329.1 - 2.2e-44 151.6 2.8 1.6e-43 148.7 1.7 2.0 2 0 0 2 2 2 1 Rad54 N terminal Helicase_C PF00271.26 XP_011273329.1 - 8.6e-13 47.9 0.0 2.5e-12 46.4 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 XP_011273329.1 - 2.8e-08 32.9 0.0 1e-07 31.0 0.0 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.24 XP_011273329.1 - 1.5e-05 24.5 0.0 7.9e-05 22.2 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 XP_011273329.1 - 6.3e-05 22.8 0.0 0.00017 21.4 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit EVE PF01878.13 XP_011273330.1 - 7.4e-48 162.2 0.1 1.1e-47 161.6 0.0 1.2 1 0 0 1 1 1 1 EVE domain Fungal_trans PF04082.13 XP_011273331.1 - 1.7e-16 59.9 3.0 1.7e-16 59.9 2.1 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 XP_011273331.1 - 3e-09 36.6 11.2 5.1e-09 35.8 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FdhD-NarQ PF02634.10 XP_011273331.1 - 1.6 8.1 3.6 31 3.8 0.0 2.2 2 0 0 2 2 2 0 FdhD/NarQ family Epimerase PF01370.16 XP_011273332.1 - 1.3e-13 50.9 0.0 2e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 XP_011273332.1 - 3.9e-11 42.1 0.0 5.3e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 XP_011273332.1 - 5.5e-08 32.0 0.0 1e-07 31.1 0.0 1.4 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 XP_011273332.1 - 2.1e-05 24.5 0.2 6.5e-05 23.0 0.2 2.0 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 XP_011273332.1 - 0.0022 17.9 0.0 0.0039 17.1 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 XP_011273332.1 - 0.051 13.2 0.0 0.12 12.0 0.0 1.5 1 1 0 1 1 1 0 KR domain Polysacc_synt_2 PF02719.10 XP_011273332.1 - 0.097 11.5 0.0 0.16 10.8 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Mob1_phocein PF03637.12 XP_011273333.1 - 5.9e-69 231.2 1.8 8e-69 230.7 1.3 1.2 1 0 0 1 1 1 1 Mob1/phocein family RNA_pol PF00940.14 XP_011273334.1 - 3.4e-158 526.3 3.0 3.4e-158 526.3 2.1 2.3 3 1 0 3 3 3 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 XP_011273334.1 - 3.2e-82 276.3 1.1 3.2e-82 276.3 0.7 2.0 2 0 0 2 2 2 1 DNA-directed RNA polymerase N-terminal RVT_2 PF07727.9 XP_011273335.1 - 8.7e-33 113.2 0.3 4.7e-32 110.8 0.0 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 XP_011273335.1 - 5.5e-05 23.2 0.0 0.00014 21.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Snf7 PF03357.16 XP_011273336.1 - 3.3e-40 137.2 21.5 3.3e-40 137.2 14.9 2.0 2 0 0 2 2 2 1 Snf7 Snapin_Pallidin PF14712.1 XP_011273336.1 - 5.1 7.4 17.2 0.7 10.2 1.4 3.3 2 1 1 3 3 3 0 Snapin/Pallidin Ribosomal_60s PF00428.14 XP_011273336.1 - 5.5 7.4 10.0 0.66 10.4 3.6 2.1 2 1 0 2 2 2 0 60s Acidic ribosomal protein Syntaxin PF00804.20 XP_011273337.1 - 1.6e-19 69.9 4.9 1.6e-19 69.9 3.4 3.7 4 1 0 4 4 4 1 Syntaxin SNARE PF05739.14 XP_011273337.1 - 1.9e-18 65.8 7.6 2.7e-18 65.4 2.1 2.9 2 1 0 2 2 2 1 SNARE domain Sed5p PF11416.3 XP_011273337.1 - 1.5e-10 40.3 9.5 2e-10 39.9 5.3 2.2 2 0 0 2 2 2 1 Integral membrane protein Sed5p MCPsignal PF00015.16 XP_011273337.1 - 0.00013 21.5 0.6 0.00013 21.5 0.4 2.9 3 0 0 3 3 3 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Syntaxin-18_N PF10496.4 XP_011273337.1 - 0.0079 16.0 1.5 0.0079 16.0 1.1 3.4 4 0 0 4 4 4 1 SNARE-complex protein Syntaxin-18 N-terminus DUF1664 PF07889.7 XP_011273337.1 - 0.013 15.3 8.1 0.1 12.3 0.3 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Vac_Fusion PF02346.11 XP_011273337.1 - 0.11 11.9 0.1 0.11 11.9 0.1 3.0 3 0 0 3 3 3 0 Chordopoxvirus fusion protein NPV_P10 PF05531.7 XP_011273337.1 - 0.3 11.3 12.5 1.5 9.0 0.8 3.6 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein zf-C4H2 PF10146.4 XP_011273337.1 - 0.68 9.9 14.1 0.6 10.0 0.8 2.4 1 1 0 2 2 2 0 Zinc finger-containing protein Spectrin PF00435.16 XP_011273337.1 - 1.2 9.4 16.0 0.12 12.6 1.0 3.7 3 2 0 3 3 3 0 Spectrin repeat AATF-Che1 PF13339.1 XP_011273337.1 - 2.7 8.1 16.6 0.43 10.7 0.2 3.2 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor FlaC_arch PF05377.6 XP_011273337.1 - 3.2 7.7 14.3 0.77 9.7 1.8 3.5 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) Laminin_II PF06009.7 XP_011273337.1 - 3.4 7.4 19.5 1.1 9.0 0.3 3.2 2 1 1 3 3 3 0 Laminin Domain II eIF3_N PF09440.5 XP_011273337.1 - 9.4 6.4 12.9 0.36 10.9 1.1 3.0 3 0 0 3 3 3 0 eIF3 subunit 6 N terminal domain CAF1C_H4-bd PF12265.3 XP_011273338.1 - 4.6e-21 74.4 0.0 1.2e-20 73.1 0.0 1.8 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.27 XP_011273338.1 - 1.3e-16 59.7 13.0 1.4e-06 27.9 0.0 5.7 7 0 0 7 7 7 3 WD domain, G-beta repeat eIF2A PF08662.6 XP_011273338.1 - 0.0063 16.2 2.1 0.0084 15.8 0.3 2.0 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A PQ-loop PF04193.9 XP_011273339.1 - 2.3e-20 71.8 24.4 2.8e-11 42.8 2.1 3.5 3 0 0 3 3 3 2 PQ loop repeat SPC12 PF06645.8 XP_011273339.1 - 4.4 7.1 11.5 4.3 7.2 2.5 3.1 3 0 0 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) MtN3_slv PF03083.11 XP_011273339.1 - 6.1 6.7 18.9 0.089 12.6 0.6 3.4 2 1 1 3 3 3 0 Sugar efflux transporter for intercellular exchange Cyclin PF08613.6 XP_011273340.1 - 1.2e-08 35.5 0.1 1.2e-08 35.5 0.1 2.2 2 0 0 2 2 2 1 Cyclin Kelch_4 PF13418.1 XP_011273341.1 - 4.8e-15 55.0 1.6 0.00012 21.7 0.0 5.0 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.1 XP_011273341.1 - 7.6e-11 41.7 0.2 0.019 14.9 0.0 4.3 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.10 XP_011273341.1 - 8.3e-10 38.0 0.6 0.2 11.5 0.0 5.2 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.1 XP_011273341.1 - 8.8e-09 35.1 3.3 0.44 10.8 0.0 5.2 4 1 1 5 5 5 2 Kelch motif BTB PF00651.26 XP_011273341.1 - 9.5e-08 32.0 0.0 2.3e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Kelch_1 PF01344.20 XP_011273341.1 - 6.4e-07 28.8 0.3 0.26 10.8 0.0 4.7 4 1 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 XP_011273341.1 - 1.8e-05 24.7 2.4 0.041 14.0 0.0 3.9 3 1 0 3 3 3 1 Galactose oxidase, central domain Rax2 PF12768.2 XP_011273341.1 - 0.0002 20.6 0.1 0.078 12.1 0.0 2.6 3 0 0 3 3 3 2 Cortical protein marker for cell polarity BACK PF07707.10 XP_011273341.1 - 0.0056 16.4 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 BTB And C-terminal Kelch WD40 PF00400.27 XP_011273342.1 - 5e-17 61.0 5.2 3.8e-07 29.7 0.0 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat DUF1162 PF06650.7 XP_011273342.1 - 0.016 14.4 0.0 0.052 12.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1162) PX PF00787.19 XP_011273343.1 - 5.2e-16 58.4 1.2 2.6e-15 56.1 0.5 2.1 2 0 0 2 2 2 1 PX domain SNARE PF05739.14 XP_011273343.1 - 1.7e-11 43.6 3.3 4.1e-11 42.3 2.3 1.7 1 0 0 1 1 1 1 SNARE domain V_ATPase_I PF01496.14 XP_011273343.1 - 0.05 11.4 3.1 0.097 10.5 2.1 1.5 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Lge1 PF11488.3 XP_011273343.1 - 6.4 7.0 12.5 1.8 8.8 0.1 3.4 2 1 1 3 3 3 0 Transcriptional regulatory protein LGE1 CRAL_TRIO PF00650.15 XP_011273344.1 - 8.3e-45 152.1 0.0 1.3e-44 151.5 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 XP_011273344.1 - 3.8e-14 52.5 0.3 2.2e-13 50.0 0.2 2.4 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 XP_011273344.1 - 1.2e-08 35.0 0.0 3.7e-08 33.3 0.0 1.8 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain CENP-I PF07778.6 XP_011273345.1 - 4.4e-47 160.4 15.4 2e-46 158.2 10.7 1.9 1 1 0 1 1 1 1 Mis6 tRNA-synt_1 PF00133.17 XP_011273346.1 - 6.8e-53 179.6 0.8 3.3e-18 65.0 0.5 6.2 2 1 3 5 5 5 5 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.1 XP_011273346.1 - 1.4e-43 148.3 0.4 3.2e-43 147.1 0.1 1.7 2 0 0 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.6 XP_011273346.1 - 8.5e-27 93.8 0.0 2.8e-21 75.6 0.0 4.1 3 1 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 XP_011273346.1 - 8.3e-09 35.3 0.0 2e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1d PF00750.14 XP_011273346.1 - 0.0011 17.9 0.0 0.002 16.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (R) Sec7 PF01369.15 XP_011273346.1 - 0.054 13.1 0.3 0.25 10.9 0.0 2.0 2 0 0 2 2 2 0 Sec7 domain SMC_N PF02463.14 XP_011273348.1 - 2.1e-15 56.5 39.5 7.6e-15 54.7 27.4 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 XP_011273348.1 - 2e-07 30.9 0.0 5.3e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 XP_011273348.1 - 0.0009 19.2 0.1 0.0009 19.2 0.1 4.0 3 1 0 3 3 3 1 AAA domain AAA_29 PF13555.1 XP_011273348.1 - 0.0037 16.7 0.0 0.0078 15.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 XP_011273348.1 - 0.055 13.7 93.9 5.2e+03 -2.5 0.1 5.4 2 1 0 2 2 2 0 AAA domain Reo_sigmaC PF04582.7 XP_011273348.1 - 2.2 7.4 12.5 2 7.4 0.4 4.0 2 2 2 4 4 4 0 Reovirus sigma C capsid protein DUF869 PF05911.6 XP_011273348.1 - 5.2 5.1 64.4 0.016 13.4 14.0 2.5 2 1 0 2 2 2 0 Plant protein of unknown function (DUF869) Uso1_p115_head PF04869.9 XP_011273349.1 - 2.4e-116 387.9 0.0 1e-115 385.7 0.0 2.3 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Filament PF00038.16 XP_011273349.1 - 1.4e-12 47.7 205.1 5e-05 22.9 36.2 8.1 1 1 5 7 7 7 6 Intermediate filament protein Myosin_tail_1 PF01576.14 XP_011273349.1 - 4e-07 28.1 120.2 4e-07 28.1 83.3 4.6 1 1 3 4 4 4 3 Myosin tail Reo_sigmaC PF04582.7 XP_011273349.1 - 1.2e-06 27.9 116.6 0.0019 17.4 7.2 8.8 1 1 7 8 8 8 7 Reovirus sigma C capsid protein WEMBL PF05701.6 XP_011273349.1 - 0.00077 18.0 69.3 0.00077 18.0 48.0 5.7 1 1 5 6 6 6 2 Weak chloroplast movement under blue light IncA PF04156.9 XP_011273349.1 - 0.00079 19.0 50.6 0.00099 18.7 19.6 11.4 1 1 11 12 12 12 4 IncA protein AAA_13 PF13166.1 XP_011273349.1 - 0.0013 17.3 42.1 0.0013 17.3 29.2 7.2 2 1 5 7 7 7 3 AAA domain Tropomyosin_1 PF12718.2 XP_011273349.1 - 0.0047 16.7 29.9 0.0047 16.7 20.7 12.4 2 1 8 11 11 11 4 Tropomyosin like CENP-F_leu_zip PF10473.4 XP_011273349.1 - 4 7.2 264.1 0.053 13.3 4.6 11.6 1 1 10 12 12 12 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Rad52_Rad22 PF04098.10 XP_011273350.1 - 2.8e-35 121.3 0.2 3.3e-35 121.1 0.1 1.1 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein DUF2874 PF11396.3 XP_011273350.1 - 0.013 15.4 4.1 0.066 13.1 0.7 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2874) GHL1-3 PF11308.3 XP_011273350.1 - 0.021 14.2 0.0 1.1 8.5 0.0 2.1 1 1 1 2 2 2 0 Glycosyl hydrolases related to GH101 family, GHL1-GHL3 IKI3 PF04762.7 XP_011273351.1 - 0 1075.4 7.3 0 1075.4 5.0 1.3 2 0 0 2 2 2 1 IKI3 family TPR_1 PF00515.23 XP_011273351.1 - 0.01 15.4 0.8 1.2 8.8 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 XP_011273351.1 - 0.98 9.4 5.1 3.1 7.9 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat RRM_1 PF00076.17 XP_011273352.1 - 1e-27 95.5 0.4 1.2e-12 47.2 0.2 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 XP_011273352.1 - 7.4e-19 67.4 0.1 2.4e-09 37.0 0.1 3.2 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 XP_011273352.1 - 6.3e-18 64.3 0.1 6.3e-09 35.5 0.1 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 XP_011273352.1 - 0.0001 22.0 0.0 0.29 10.9 0.0 2.8 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 XP_011273352.1 - 0.00072 19.3 0.5 1.3 8.8 0.2 3.4 3 0 0 3 3 3 2 RNA binding motif Sigma70_ner PF04546.8 XP_011273352.1 - 0.15 11.6 2.1 1.2 8.7 0.6 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region JAB PF01398.16 XP_011273353.1 - 2e-30 104.8 0.0 3.8e-30 103.9 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 XP_011273353.1 - 3.4e-08 32.9 0.0 5.8e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.8 XP_011273353.1 - 0.00025 20.5 0.1 0.0028 17.1 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0172) Lactonase PF10282.4 XP_011273354.1 - 0.018 14.1 0.0 0.028 13.4 0.0 1.2 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller WD40 PF00400.27 XP_011273354.1 - 0.28 11.1 6.1 3.1 7.8 0.1 4.3 5 0 0 5 5 5 0 WD domain, G-beta repeat UCH PF00443.24 XP_011273355.1 - 7.7e-55 185.8 2.0 7.7e-55 185.8 1.4 2.4 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 XP_011273355.1 - 1.8e-19 70.3 0.5 1.8e-19 70.3 0.3 2.4 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 XP_011273355.1 - 0.014 14.7 0.9 0.049 12.9 0.1 2.3 2 1 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Ribosomal_L11 PF00298.14 XP_011273356.1 - 1.5e-27 95.5 0.6 2.2e-27 94.9 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.9 XP_011273356.1 - 1.4e-25 88.5 0.6 1.4e-25 88.5 0.4 1.6 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain EAL PF00563.15 XP_011273356.1 - 0.09 12.2 0.0 1 8.7 0.0 1.9 2 0 0 2 2 2 0 EAL domain Pkinase PF00069.20 XP_011273357.1 - 1.4e-56 191.4 0.0 1.1e-55 188.6 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011273357.1 - 1e-19 70.6 0.0 2.1e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 XP_011273357.1 - 0.19 10.7 0.3 0.62 9.0 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 XP_011273357.1 - 0.2 11.3 0.0 0.35 10.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family adh_short PF00106.20 XP_011273358.1 - 4.7e-13 49.3 0.0 8.1e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 XP_011273358.1 - 6.9e-09 35.6 0.0 1e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 XP_011273358.1 - 0.01 15.2 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 XP_011273358.1 - 0.062 12.2 0.0 0.13 11.1 0.0 1.5 1 0 0 1 1 1 0 Male sterility protein NAD_binding_10 PF13460.1 XP_011273358.1 - 0.071 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding WD40 PF00400.27 XP_011273359.1 - 1.6e-12 46.7 1.2 0.00095 18.9 0.0 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat Cep57_CLD PF14073.1 XP_011273359.1 - 0.076 12.8 3.4 0.11 12.3 2.3 1.2 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 DUF1296 PF06972.6 XP_011273359.1 - 0.11 12.4 1.9 11 6.1 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1296) DUF1777 PF08648.7 XP_011273360.1 - 1.3e-18 67.3 21.5 1.7e-18 66.9 14.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) MAM1 PF10434.4 XP_011273360.1 - 0.024 13.8 2.1 0.032 13.4 1.4 1.2 1 0 0 1 1 1 0 Monopolin complex protein MAM1 Tis11B_N PF04553.7 XP_011273360.1 - 2.7 8.2 7.1 2.2 8.4 1.1 2.3 2 1 0 2 2 2 0 Tis11B like protein, N terminus Macoilin PF09726.4 XP_011273360.1 - 3.9 5.6 7.9 4.2 5.5 5.5 1.1 1 0 0 1 1 1 0 Transmembrane protein RRM_1 PF00076.17 XP_011273361.1 - 1.5e-09 37.3 0.0 5.3e-09 35.5 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 XP_011273361.1 - 3.5e-08 33.3 0.0 7.7e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CDC45 PF02724.9 XP_011273361.1 - 0.21 9.6 4.9 0.21 9.5 3.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Ycf1 PF05758.7 XP_011273361.1 - 0.34 8.5 5.6 0.37 8.4 3.9 1.1 1 0 0 1 1 1 0 Ycf1 Neuregulin PF02158.10 XP_011273361.1 - 1 8.0 5.9 0.095 11.4 1.0 1.5 2 0 0 2 2 2 0 Neuregulin family RNA_pol_Rpc4 PF05132.9 XP_011273361.1 - 8.9 6.3 11.3 1.9 8.4 4.7 2.0 2 0 0 2 2 2 0 RNA polymerase III RPC4 YqfQ PF14181.1 XP_011273361.1 - 9.3 6.2 17.4 2 8.4 8.7 2.0 2 0 0 2 2 2 0 YqfQ-like protein Ras PF00071.17 XP_011273362.1 - 1e-57 194.0 0.0 1.3e-57 193.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 XP_011273362.1 - 1.7e-17 64.0 0.0 3.4e-17 63.0 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 XP_011273362.1 - 2.2e-11 43.2 0.0 3.2e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 XP_011273362.1 - 5.3e-06 26.0 0.0 2.2e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 XP_011273362.1 - 0.06 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Alpha_GJ PF03229.8 XP_011273363.1 - 2.6 8.3 15.8 3.4 8.0 11.0 1.2 1 0 0 1 1 1 0 Alphavirus glycoprotein J Ribosomal_S3_C PF00189.15 XP_011273364.1 - 6.9e-16 58.2 0.1 1.6e-15 57.0 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 XP_011273364.1 - 5.4e-12 45.0 0.0 2.8e-11 42.8 0.0 2.0 2 0 0 2 2 2 1 KH domain SHR3_chaperone PF08229.6 XP_011273365.1 - 2e-70 235.7 0.1 2.6e-70 235.3 0.1 1.2 1 1 0 1 1 1 1 ER membrane protein SH3 Mito_carr PF00153.22 XP_011273366.1 - 2.4e-44 148.9 3.1 6e-17 61.1 0.0 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein SecE PF00584.15 XP_011273366.1 - 0.041 13.4 1.3 0.054 13.0 0.0 1.9 2 0 0 2 2 2 0 SecE/Sec61-gamma subunits of protein translocation complex TRAPPC10 PF12584.3 XP_011273368.1 - 5.4e-22 77.8 0.6 1.2e-21 76.7 0.4 1.7 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Foie-gras_1 PF11817.3 XP_011273368.1 - 0.00025 20.6 0.0 0.0029 17.1 0.0 2.1 2 0 0 2 2 2 1 Foie gras liver health family 1 DUF4649 PF15507.1 XP_011273368.1 - 0.0019 17.8 0.5 0.014 15.1 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4649) HEM4 PF02602.10 XP_011273369.1 - 5e-36 124.1 0.0 5.6e-36 123.9 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD RRM_1 PF00076.17 XP_011273370.1 - 1.1e-05 24.9 0.0 1.9e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 XP_011273370.1 - 2.9e-05 23.8 0.0 4.3e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 XP_011273370.1 - 0.0011 18.8 0.0 0.0019 18.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Ank PF00023.25 XP_011273371.1 - 1.9e-15 55.7 0.0 7.1e-08 31.8 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat TIG PF01833.19 XP_011273371.1 - 5.4e-11 42.3 1.0 5.4e-11 42.3 0.7 3.2 4 0 0 4 4 4 1 IPT/TIG domain Ank_2 PF12796.2 XP_011273371.1 - 5.6e-10 39.4 0.1 1.2e-09 38.3 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 XP_011273371.1 - 1.9e-09 37.4 0.0 9.7e-08 32.0 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 XP_011273371.1 - 3.7e-08 33.6 0.0 3.6e-07 30.5 0.0 2.4 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 XP_011273371.1 - 2.5e-07 30.2 0.0 0.017 15.3 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat WD40 PF00400.27 XP_011273372.1 - 3.5e-33 112.2 0.7 1.6e-09 37.3 0.0 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 XP_011273372.1 - 0.0039 15.4 0.3 0.81 7.7 0.0 2.3 2 0 0 2 2 2 2 Nucleoporin Nup120/160 AlaDh_PNT_N PF05222.10 XP_011273373.1 - 5.1e-30 104.2 0.0 7.6e-30 103.6 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 XP_011273373.1 - 5.1e-19 68.4 0.2 1e-18 67.4 0.0 1.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain DUF1900 PF08954.6 XP_011273373.1 - 0.061 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1900) TPR_2 PF07719.12 XP_011273374.1 - 2e-37 124.0 9.4 0.00013 21.6 0.1 10.7 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_11 PF13414.1 XP_011273374.1 - 9.9e-34 114.8 20.1 3.2e-11 42.7 0.1 7.2 6 1 1 7 7 7 6 TPR repeat TPR_1 PF00515.23 XP_011273374.1 - 1.9e-32 109.5 17.3 2.4e-05 23.7 0.0 10.4 10 0 0 10 10 10 7 Tetratricopeptide repeat Apc3 PF12895.2 XP_011273374.1 - 5.4e-27 93.7 15.5 4.5e-22 77.9 0.2 5.1 4 2 2 6 6 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 XP_011273374.1 - 2.9e-23 79.8 16.1 0.00034 20.1 0.0 9.3 9 1 1 10 10 10 4 Tetratricopeptide repeat TPR_12 PF13424.1 XP_011273374.1 - 9.2e-22 76.7 15.3 3.7e-07 29.9 0.0 8.2 4 2 4 9 9 9 4 Tetratricopeptide repeat TPR_19 PF14559.1 XP_011273374.1 - 3.9e-18 65.5 2.9 0.023 15.0 0.0 7.9 4 2 5 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.1 XP_011273374.1 - 9.9e-18 64.3 0.0 0.012 16.2 0.0 6.5 6 1 0 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.1 XP_011273374.1 - 1.5e-15 55.6 2.9 0.26 11.1 0.0 8.0 8 1 1 9 9 8 4 Tetratricopeptide repeat TPR_14 PF13428.1 XP_011273374.1 - 1.9e-15 55.9 0.0 4.9 8.0 0.0 8.1 5 2 3 8 8 7 2 Tetratricopeptide repeat TPR_17 PF13431.1 XP_011273374.1 - 6.8e-15 53.9 4.1 0.012 15.7 0.0 8.6 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_10 PF13374.1 XP_011273374.1 - 1.2e-10 40.9 0.5 0.036 14.0 0.0 7.5 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.1 XP_011273374.1 - 2.9e-09 36.6 0.0 0.00022 21.0 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 XP_011273374.1 - 1e-06 28.7 0.6 18 6.0 0.2 7.3 7 0 0 7 7 7 0 Tetratricopeptide repeat DUF273 PF03314.9 XP_011273374.1 - 0.0048 16.2 0.1 0.0087 15.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF273 TPR_15 PF13429.1 XP_011273374.1 - 0.014 14.4 0.3 1.7 7.5 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_3 PF07720.7 XP_011273374.1 - 0.016 14.9 2.8 1.9 8.3 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR PF01535.15 XP_011273374.1 - 0.031 14.2 4.6 36 4.6 0.0 5.6 6 0 0 6 6 5 0 PPR repeat Fis1_TPR_C PF14853.1 XP_011273374.1 - 0.16 11.8 5.1 60 3.6 0.0 5.6 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_21 PF09976.4 XP_011273374.1 - 0.21 11.5 1.1 35 4.3 0.0 4.3 3 1 0 3 3 3 0 Tetratricopeptide repeat ADK PF00406.17 XP_011273376.1 - 7.9e-46 155.6 0.0 1.1e-45 155.2 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 XP_011273376.1 - 6.2e-09 36.2 0.0 1.3e-08 35.2 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 XP_011273376.1 - 6.1e-08 33.5 0.0 1.1e-07 32.7 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 XP_011273376.1 - 3.3e-07 30.2 0.0 6.4e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 XP_011273376.1 - 0.0054 16.1 0.1 0.76 9.1 0.1 2.3 2 0 0 2 2 2 2 Thymidylate kinase Zeta_toxin PF06414.7 XP_011273376.1 - 0.012 14.7 0.0 0.015 14.3 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin adh_short PF00106.20 XP_011273377.1 - 5.6e-23 81.6 0.0 6.5e-23 81.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 XP_011273377.1 - 1.8e-14 54.1 1.0 2.1e-14 53.8 0.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 XP_011273377.1 - 4.9e-09 36.1 0.0 6.3e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 KR domain TrkA_N PF02254.13 XP_011273377.1 - 0.00066 19.6 0.2 0.0015 18.4 0.1 1.7 1 0 0 1 1 1 1 TrkA-N domain DUF1776 PF08643.5 XP_011273377.1 - 0.006 15.7 0.0 0.0093 15.1 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) RNase_P_p30 PF01876.11 XP_011273377.1 - 0.018 14.2 1.1 0.037 13.2 0.3 2.0 2 1 0 2 2 2 0 RNase P subunit p30 Polysacc_synt_2 PF02719.10 XP_011273377.1 - 0.076 11.8 0.4 0.11 11.3 0.3 1.3 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_3 PF03447.11 XP_011273377.1 - 0.11 12.8 1.0 2.7 8.4 0.1 2.9 3 1 0 3 3 3 0 Homoserine dehydrogenase, NAD binding domain DUF3840 PF12944.2 XP_011273377.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3840) Pkinase PF00069.20 XP_011273378.1 - 2.6e-07 30.0 0.3 6.1e-07 28.8 0.1 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011273378.1 - 0.00033 19.8 0.0 0.00078 18.5 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase G-alpha PF00503.15 XP_011273380.1 - 1.3e-118 396.1 8.1 1.6e-118 395.7 5.6 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 XP_011273380.1 - 3.4e-15 55.7 0.2 3.8e-10 39.2 0.0 2.7 2 0 0 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 XP_011273380.1 - 0.00015 22.2 0.0 0.28 11.6 0.0 2.8 2 1 0 2 2 2 2 Miro-like protein Gtr1_RagA PF04670.7 XP_011273380.1 - 0.00024 20.3 0.6 0.042 12.9 0.1 2.5 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.12 XP_011273380.1 - 0.034 13.6 0.3 0.12 11.8 0.0 1.9 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 XP_011273380.1 - 0.037 13.4 0.1 2 7.8 0.0 2.5 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain MutS_V PF00488.16 XP_011273380.1 - 0.04 13.3 0.0 0.5 9.7 0.0 2.1 2 0 0 2 2 2 0 MutS domain V AAA_29 PF13555.1 XP_011273380.1 - 0.057 12.9 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ParBc PF02195.13 XP_011273382.1 - 5.9e-12 45.5 0.0 7.2e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 ParB-like nuclease domain PHO4 PF01384.15 XP_011273383.1 - 2.8e-120 400.8 0.0 4.7e-120 400.1 0.0 1.4 1 1 0 1 1 1 1 Phosphate transporter family Glycophorin_A PF01102.13 XP_011273383.1 - 0.15 11.8 2.7 0.21 11.3 0.0 2.5 3 0 0 3 3 3 0 Glycophorin A Ldh_1_N PF00056.18 XP_011273384.1 - 2e-43 147.5 0.1 3.8e-43 146.6 0.1 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 XP_011273384.1 - 8.6e-42 142.8 0.1 1.2e-41 142.2 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 XP_011273384.1 - 0.0003 19.5 0.0 0.00044 19.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.11 XP_011273384.1 - 0.043 13.1 0.2 0.18 11.1 0.1 1.9 1 1 0 2 2 2 0 Family 4 glycosyl hydrolase NOB1_Zn_bind PF08772.6 XP_011273385.1 - 1.5e-25 88.7 0.4 3.6e-25 87.5 0.3 1.7 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like SGS PF05002.10 XP_011273386.1 - 3.9e-27 93.8 1.8 3.9e-27 93.8 1.3 2.9 3 0 0 3 3 3 1 SGS domain CS PF04969.11 XP_011273386.1 - 1.3e-11 44.8 2.8 3.6e-11 43.4 1.9 1.7 1 0 0 1 1 1 1 CS domain TPR_16 PF13432.1 XP_011273386.1 - 3e-06 27.7 1.5 3.8e-05 24.2 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 XP_011273386.1 - 2.2e-05 23.9 0.1 2.2e-05 23.9 0.1 3.0 4 0 0 4 4 4 1 TPR repeat TPR_12 PF13424.1 XP_011273386.1 - 0.00067 19.5 1.3 0.00067 19.5 0.9 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 XP_011273386.1 - 0.002 18.2 5.5 0.011 15.8 2.3 2.4 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 XP_011273386.1 - 0.0034 17.6 7.7 0.0057 16.9 1.0 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 XP_011273386.1 - 0.0042 16.8 7.5 0.19 11.6 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 XP_011273386.1 - 0.0074 15.8 11.2 0.62 9.7 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 XP_011273386.1 - 0.16 12.7 0.3 7.8 7.4 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1374 PF07118.6 XP_011273386.1 - 1 9.4 9.1 5 7.2 3.5 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1374) MAP65_ASE1 PF03999.7 XP_011273387.1 - 2.3e-66 224.7 21.2 2.3e-66 224.7 14.7 3.0 2 2 1 3 3 3 1 Microtubule associated protein (MAP65/ASE1 family) PT PF04886.7 XP_011273387.1 - 6.8e-05 22.0 15.6 0.00016 20.9 10.8 1.6 1 0 0 1 1 1 1 PT repeat MCC-bdg_PDZ PF10506.4 XP_011273387.1 - 0.036 13.8 1.7 0.15 11.9 1.2 2.2 1 0 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Peptidase_S32 PF05579.8 XP_011273387.1 - 0.31 9.9 0.0 0.57 9.0 0.0 1.3 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 Pkinase PF00069.20 XP_011273388.1 - 3.7e-43 147.5 0.0 5e-43 147.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011273388.1 - 8.9e-16 57.7 0.0 1.2e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 XP_011273388.1 - 7.7e-14 51.5 0.3 1.4e-13 50.7 0.2 1.4 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 XP_011273388.1 - 0.00071 18.6 0.0 0.00099 18.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 XP_011273388.1 - 0.0073 15.3 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 XP_011273388.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Whi5 PF08528.6 XP_011273389.1 - 5.6e-10 38.5 0.1 1.4e-09 37.2 0.1 1.8 1 0 0 1 1 1 1 Whi5 like Abhydrolase_6 PF12697.2 XP_011273390.1 - 5.2e-24 85.4 0.0 6.8e-24 85.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 XP_011273390.1 - 1.6e-09 37.6 0.0 3.3e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 XP_011273390.1 - 2.5e-07 30.5 0.0 6.3e-07 29.2 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 XP_011273390.1 - 0.055 12.8 0.0 0.096 12.0 0.0 1.5 1 0 0 1 1 1 0 Putative esterase Abhydrolase_6 PF12697.2 XP_011273391.1 - 4.3e-24 85.6 0.0 5.1e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 XP_011273391.1 - 1.1e-08 34.8 0.0 2.4e-08 33.8 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.15 XP_011273391.1 - 1.1e-05 25.0 0.0 2.1e-05 24.1 0.0 1.6 1 1 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 XP_011273391.1 - 3.7e-05 23.5 0.0 0.0001 22.0 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 XP_011273391.1 - 0.04 13.3 0.2 0.12 11.7 0.0 1.9 3 0 0 3 3 3 0 Serine hydrolase (FSH1) PGAP1 PF07819.8 XP_011273391.1 - 0.043 13.3 0.0 0.078 12.5 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Peptidase_S9 PF00326.16 XP_011273391.1 - 0.048 12.8 0.0 0.083 12.1 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family UPF0227 PF05728.7 XP_011273391.1 - 0.062 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) SRP40_C PF05022.7 XP_011273392.1 - 5.9e-30 103.5 6.0 2e-29 101.8 4.1 2.0 1 0 0 1 1 1 1 SRP40, C-terminal domain Utp14 PF04615.8 XP_011273392.1 - 1.3 7.1 65.2 1.6 6.8 45.2 1.1 1 0 0 1 1 1 0 Utp14 protein Helicase_C_3 PF13625.1 XP_011273393.1 - 3.1e-26 91.6 0.1 2e-25 89.0 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 XP_011273393.1 - 7.3e-14 52.0 0.0 1.7e-13 50.8 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 XP_011273393.1 - 2.5e-12 46.1 0.0 4e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 XP_011273393.1 - 1.4e-10 40.8 0.0 3.4e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 XP_011273393.1 - 7.8e-08 31.9 0.0 1.6e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_34 PF13872.1 XP_011273393.1 - 0.025 13.3 0.0 0.043 12.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 SBP_bac_6 PF13343.1 XP_011273393.1 - 0.032 13.5 0.0 0.076 12.3 0.0 1.6 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein Ndc80_HEC PF03801.8 XP_011273394.1 - 4.5e-56 188.6 1.8 8.4e-56 187.8 0.6 2.0 1 1 0 1 1 1 1 HEC/Ndc80p family Bacillus_HBL PF05791.6 XP_011273394.1 - 0.00037 19.9 9.2 0.00037 19.9 6.4 3.5 2 1 1 3 3 3 1 Bacillus haemolytic enterotoxin (HBL) EMP24_GP25L PF01105.19 XP_011273394.1 - 0.0066 16.1 4.3 0.0066 16.1 3.0 3.1 2 1 1 3 3 3 1 emp24/gp25L/p24 family/GOLD DUF1494 PF07379.6 XP_011273394.1 - 0.074 12.9 5.9 0.041 13.7 1.0 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF1494) Reo_sigmaC PF04582.7 XP_011273394.1 - 0.27 10.3 14.3 0.2 10.7 3.3 2.6 2 0 0 2 2 2 0 Reovirus sigma C capsid protein MCPsignal PF00015.16 XP_011273394.1 - 1.7 8.1 23.4 0.57 9.6 4.3 2.4 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF2730 PF10805.3 XP_011273394.1 - 1.9 8.2 14.2 0.14 11.8 3.0 3.6 2 1 2 4 4 4 0 Protein of unknown function (DUF2730) PTPlike_phytase PF14566.1 XP_011273394.1 - 3.1 7.8 8.4 0.34 10.9 2.0 2.2 2 0 0 2 2 2 0 Inositol hexakisphosphate Mnd1 PF03962.10 XP_011273394.1 - 7.9 6.0 34.8 0.99 9.0 11.2 3.1 2 2 0 2 2 2 0 Mnd1 family SH3_1 PF00018.23 XP_011273395.1 - 8.2e-08 31.5 0.0 2.1e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 SH3 domain PX PF00787.19 XP_011273395.1 - 4.2e-07 29.7 0.2 4.2e-07 29.7 0.1 2.4 3 1 0 3 3 3 1 PX domain SH3_9 PF14604.1 XP_011273395.1 - 3.4e-06 26.5 0.0 6.8e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PB1 PF00564.19 XP_011273395.1 - 8.6e-05 22.1 0.2 0.00019 21.0 0.1 1.6 1 0 0 1 1 1 1 PB1 domain SH3_2 PF07653.12 XP_011273395.1 - 0.00023 20.5 0.0 0.00044 19.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 XP_011273395.1 - 0.049 13.8 0.0 2.6 8.3 0.0 2.4 2 0 0 2 2 2 0 Bacterial SH3 domain Git3 PF11710.3 XP_011273396.1 - 7.4e-29 100.7 20.6 1.8e-16 60.3 4.1 2.8 1 1 0 2 2 2 2 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 XP_011273396.1 - 1.3e-19 69.7 2.7 1.1e-18 66.7 0.4 2.5 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term bZIP_1 PF00170.16 XP_011273397.1 - 9.4e-07 28.7 15.0 2.3e-06 27.4 10.4 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 XP_011273397.1 - 0.0053 16.5 17.4 0.0053 16.5 12.0 2.1 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 XP_011273397.1 - 0.025 14.8 8.7 0.025 14.8 6.0 2.0 2 0 0 2 2 2 0 bZIP Maf transcription factor LMBR1 PF04791.11 XP_011273397.1 - 0.17 10.4 8.0 0.2 10.1 5.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Glutaredoxin2_C PF04399.8 XP_011273397.1 - 0.86 9.1 7.1 0.12 11.9 1.9 1.7 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain V_ATPase_I PF01496.14 XP_011273397.1 - 1.4 6.7 7.1 1.6 6.5 4.9 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Adeno_PIX PF03955.9 XP_011273397.1 - 3.2 8.3 4.9 3.5 8.2 1.4 2.2 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) MFS_1 PF07690.11 XP_011273398.1 - 2.8e-26 92.0 14.4 2.8e-26 92.0 10.0 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Spc97_Spc98 PF04130.8 XP_011273399.1 - 1.6e-92 310.5 36.1 1.6e-92 310.5 25.0 1.7 2 0 0 2 2 2 1 Spc97 / Spc98 family STAT_int PF02865.12 XP_011273399.1 - 2.8 7.9 7.6 1.4 8.8 1.1 3.1 2 2 2 4 4 4 0 STAT protein, protein interaction domain Proteasome PF00227.21 XP_011273400.1 - 5.2e-53 179.1 0.1 7.2e-53 178.6 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 XP_011273400.1 - 1.6e-13 49.6 0.1 3.8e-13 48.4 0.1 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF3839 PF12943.2 XP_011273400.1 - 0.057 12.5 0.0 0.084 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3839) Bromodomain PF00439.20 XP_011273401.1 - 3.2e-25 87.8 1.3 7.4e-25 86.6 0.9 1.7 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 XP_011273401.1 - 1.2e-08 34.9 0.1 2.6e-08 33.8 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 XP_011273401.1 - 2.7e-08 33.7 0.0 4.7e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 XP_011273401.1 - 0.0015 18.6 0.0 0.0029 17.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF1492 PF07374.6 XP_011273401.1 - 0.005 16.9 0.1 0.013 15.5 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1492) FAM176 PF14851.1 XP_011273401.1 - 0.93 9.1 11.2 2.2 7.9 7.8 1.6 1 0 0 1 1 1 0 FAM176 family PBP1_TM PF14812.1 XP_011273401.1 - 0.99 9.7 16.7 2.1 8.7 11.6 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Vfa1 PF08432.5 XP_011273401.1 - 1.2 9.1 14.0 2.2 8.2 9.7 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF4407 PF14362.1 XP_011273401.1 - 2 7.3 6.2 2.6 6.9 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Daxx PF03344.10 XP_011273401.1 - 2.8 6.3 17.7 3.5 5.9 12.2 1.1 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 XP_011273401.1 - 3.7 5.3 21.2 4.8 4.9 14.7 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 XP_011273401.1 - 4.7 5.1 12.5 6.6 4.6 8.7 1.2 1 0 0 1 1 1 0 CDC45-like protein RdRP_4 PF02123.11 XP_011273402.1 - 0.044 12.5 0.3 0.08 11.6 0.2 1.3 1 0 0 1 1 1 0 Viral RNA-directed RNA-polymerase ThiF PF00899.16 XP_011273403.1 - 8.6e-32 109.8 0.0 1.5e-31 109.0 0.0 1.4 1 0 0 1 1 1 1 ThiF family Toprim PF01751.17 XP_011273403.1 - 0.0022 17.9 0.1 0.014 15.3 0.0 2.1 2 0 0 2 2 2 1 Toprim domain Shikimate_DH PF01488.15 XP_011273403.1 - 0.0035 17.4 0.0 0.026 14.6 0.0 2.3 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 XP_011273403.1 - 0.16 11.0 0.0 0.53 9.4 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NMD3 PF04981.8 XP_011273404.1 - 3.2e-74 249.0 2.6 3.2e-74 249.0 1.8 1.6 2 0 0 2 2 2 1 NMD3 family VPS11_C PF12451.3 XP_011273404.1 - 0.071 12.9 0.8 0.19 11.6 0.5 1.7 1 0 0 1 1 1 0 Vacuolar protein sorting protein 11 C terminal FYVE PF01363.16 XP_011273404.1 - 0.73 9.7 5.5 1.7 8.5 2.0 2.4 2 0 0 2 2 2 0 FYVE zinc finger HypA PF01155.14 XP_011273404.1 - 3.6 7.3 8.3 13 5.4 0.0 3.0 2 1 1 3 3 3 0 Hydrogenase expression/synthesis hypA family TFIIB PF00382.14 XP_011273405.1 - 7e-51 169.9 0.5 1.1e-24 85.9 0.0 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 XP_011273405.1 - 2.2e-22 79.1 7.9 3.6e-22 78.3 4.4 2.1 2 0 0 2 2 2 1 Brf1-like TBP-binding domain Cyclin_N PF00134.18 XP_011273405.1 - 6.1e-07 29.0 0.4 0.0081 15.7 0.2 2.5 2 0 0 2 2 2 2 Cyclin, N-terminal domain TF_Zn_Ribbon PF08271.7 XP_011273405.1 - 3.6e-06 26.2 2.8 6.5e-06 25.3 2.0 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding SDA1 PF05285.7 XP_011273406.1 - 2.2e-100 336.1 35.4 2.6e-100 335.8 20.7 2.1 2 0 0 2 2 2 2 SDA1 NUC130_3NT PF08158.7 XP_011273406.1 - 3.7e-23 81.5 0.1 1e-22 80.1 0.1 1.8 1 0 0 1 1 1 1 NUC130/3NT domain DEAD PF00270.24 XP_011273407.1 - 5e-38 130.2 0.0 6.7e-37 126.5 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 XP_011273407.1 - 3.4e-28 97.3 0.1 7e-28 96.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4446 PF14584.1 XP_011273407.1 - 1 9.2 5.3 12 5.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) SecA_DEAD PF07517.9 XP_011273407.1 - 3.1 6.9 7.0 6.6 5.9 2.3 2.6 2 1 0 2 2 2 0 SecA DEAD-like domain GTP1_OBG PF01018.17 XP_011273408.1 - 1.9e-26 92.6 6.0 1e-19 70.7 3.2 2.2 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.18 XP_011273408.1 - 1.4e-21 76.6 0.0 2.6e-21 75.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 XP_011273408.1 - 2.1e-09 36.8 0.0 3.3e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.16 XP_011273408.1 - 2e-07 30.4 0.0 4.2e-07 29.3 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 XP_011273408.1 - 4.3e-05 22.9 0.0 0.00017 21.0 0.0 1.8 2 0 0 2 2 2 1 Ras family Miro PF08477.8 XP_011273408.1 - 0.0012 19.3 0.0 0.0028 18.1 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein AAA_17 PF13207.1 XP_011273408.1 - 0.031 15.0 0.4 1 10.1 0.1 2.8 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 XP_011273408.1 - 0.045 13.5 0.0 7.9 6.2 0.0 2.4 1 1 0 2 2 2 0 Dynamin family ABC_tran PF00005.22 XP_011273408.1 - 0.064 13.5 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA PF00004.24 XP_011273408.1 - 0.11 12.7 0.1 14 5.9 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.1 XP_011273408.1 - 0.15 11.9 6.5 0.19 11.6 0.1 3.2 3 1 0 3 3 3 0 AAA domain ATP-grasp_2 PF08442.5 XP_011273409.1 - 1.6e-71 239.8 0.8 3.3e-71 238.8 0.1 1.7 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.14 XP_011273409.1 - 3.8e-26 91.5 0.9 6.9e-26 90.6 0.2 1.7 2 0 0 2 2 2 1 CoA-ligase ATP-grasp_5 PF13549.1 XP_011273409.1 - 4.5e-08 32.5 0.4 1.1e-07 31.2 0.3 1.7 1 1 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 XP_011273409.1 - 0.00065 19.3 1.5 0.0057 16.2 0.0 2.7 2 1 1 3 3 3 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DUF2702 PF10863.3 XP_011273410.1 - 4.2e-35 120.5 13.6 4.2e-35 120.5 9.4 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2702) DUF3245 PF11595.3 XP_011273410.1 - 0.53 10.5 19.0 6.4 7.0 9.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) DUF3744 PF12558.3 XP_011273410.1 - 5.9 7.4 11.6 2.7 8.4 3.4 2.8 2 1 1 3 3 3 0 ATP-binding cassette cobalt transporter HSF_DNA-bind PF00447.12 XP_011273411.1 - 6.2e-29 100.2 10.1 6.2e-29 100.2 7.0 3.7 2 1 0 2 2 2 1 HSF-type DNA-binding ArsA_ATPase PF02374.10 XP_011273412.1 - 1.6e-104 349.2 0.3 1.8e-104 349.0 0.2 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 XP_011273412.1 - 1e-11 44.6 0.5 1.8e-11 43.8 0.3 1.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 XP_011273412.1 - 8.5e-06 25.7 0.2 2e-05 24.5 0.1 1.6 1 1 0 1 1 1 1 AAA domain PIF1 PF05970.9 XP_011273412.1 - 0.0026 16.7 0.0 0.13 11.2 0.0 2.2 2 0 0 2 2 2 1 PIF1-like helicase Fer4_NifH PF00142.13 XP_011273412.1 - 0.0056 15.8 0.0 0.017 14.3 0.0 1.7 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 XP_011273412.1 - 0.0064 15.9 0.6 0.64 9.4 0.0 3.1 4 0 0 4 4 4 1 SRP54-type protein, GTPase domain NB-ARC PF00931.17 XP_011273412.1 - 0.018 13.8 0.0 0.035 12.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_25 PF13481.1 XP_011273412.1 - 0.17 11.2 0.0 0.29 10.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain DLH PF01738.13 XP_011273413.1 - 2.2e-28 99.0 0.0 2.4e-28 98.8 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 XP_011273413.1 - 3.8e-08 33.1 0.0 5.1e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 XP_011273413.1 - 0.001 18.3 0.0 0.0046 16.2 0.0 2.1 3 0 0 3 3 3 1 Prolyl oligopeptidase family DUF2305 PF10230.4 XP_011273413.1 - 0.0032 16.9 0.0 0.0085 15.5 0.0 1.6 1 1 1 2 2 2 1 Uncharacterised conserved protein (DUF2305) Chlorophyllase PF07224.6 XP_011273413.1 - 0.0039 16.0 0.2 0.0089 14.8 0.1 1.5 1 1 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.2 XP_011273413.1 - 0.0056 15.6 0.0 0.0069 15.3 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Syja_N PF02383.13 XP_011273414.1 - 2.9e-58 197.1 8.2 8.6e-58 195.5 2.6 2.7 2 1 0 2 2 2 1 SacI homology domain hSac2 PF12456.3 XP_011273414.1 - 3.8e-08 32.7 0.1 9.9e-08 31.3 0.1 1.7 1 0 0 1 1 1 1 Inositol phosphatase MUG113 PF13455.1 XP_011273415.1 - 8.1e-12 45.4 0.1 8.1e-12 45.4 0.1 2.5 2 1 0 2 2 2 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 XP_011273415.1 - 1.2e-11 44.9 3.5 3.8e-11 43.2 0.7 2.9 1 1 1 2 2 2 1 T5orf172 domain zf-primase PF09329.6 XP_011273415.1 - 0.01 15.3 3.8 0.01 15.3 2.6 2.0 2 0 0 2 2 2 0 Primase zinc finger Glyco_transf_15 PF01793.11 XP_011273416.1 - 2.8e-137 457.1 17.4 3.8e-137 456.6 12.1 1.2 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Ribosomal_L1 PF00687.16 XP_011273417.1 - 1.9e-42 145.1 6.8 2.3e-42 144.8 4.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family eRF1_1 PF03463.10 XP_011273417.1 - 0.034 13.7 0.0 1.6 8.3 0.1 2.5 2 1 0 2 2 2 0 eRF1 domain 1 DUF3885 PF13021.1 XP_011273417.1 - 0.054 13.2 0.2 0.16 11.6 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3885) His_Phos_2 PF00328.17 XP_011273418.1 - 2e-08 33.9 0.2 8.4e-06 25.3 0.1 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PITH PF06201.8 XP_011273419.1 - 1.4e-32 112.5 1.2 1.7e-32 112.3 0.1 1.6 2 0 0 2 2 2 1 PITH domain Thioredoxin PF00085.15 XP_011273419.1 - 3.4e-24 84.5 0.1 6.3e-24 83.6 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 XP_011273419.1 - 7e-09 35.7 1.7 4.9e-07 29.7 0.1 2.8 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.1 XP_011273419.1 - 2.4e-07 30.9 0.1 1.7e-06 28.2 0.1 2.3 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.1 XP_011273419.1 - 4.2e-06 26.3 0.1 7.5e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.16 XP_011273419.1 - 1.5e-05 24.6 0.0 2.9e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.1 XP_011273419.1 - 2.7e-05 24.1 0.1 6e-05 22.9 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin-like TraF PF13728.1 XP_011273419.1 - 0.0076 15.7 0.1 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein Redoxin PF08534.5 XP_011273419.1 - 0.019 14.5 0.0 0.035 13.6 0.0 1.5 1 0 0 1 1 1 0 Redoxin Glutaredoxin PF00462.19 XP_011273419.1 - 0.078 12.9 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin DEAD PF00270.24 XP_011273420.1 - 7.7e-43 145.9 3.3 8.8e-43 145.7 0.9 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 XP_011273420.1 - 1.6e-28 98.4 0.2 8.2e-28 96.0 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 XP_011273420.1 - 0.00024 20.9 0.9 0.0017 18.2 0.1 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 XP_011273420.1 - 0.00043 19.9 0.2 0.00099 18.7 0.2 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 XP_011273420.1 - 0.001 19.2 0.1 0.0025 17.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 XP_011273420.1 - 0.0018 17.9 0.4 0.0018 17.9 0.3 1.9 2 0 0 2 2 2 1 Part of AAA domain CMS1 PF14617.1 XP_011273420.1 - 0.0063 15.6 0.2 0.028 13.4 0.0 2.1 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit Helicase_C_2 PF13307.1 XP_011273420.1 - 0.031 14.2 0.0 0.074 12.9 0.0 1.6 1 0 0 1 1 1 0 Helicase C-terminal domain Flavi_DEAD PF07652.9 XP_011273420.1 - 0.033 13.9 0.2 0.15 11.7 0.1 2.1 1 1 0 1 1 1 0 Flavivirus DEAD domain AAA_11 PF13086.1 XP_011273420.1 - 0.12 11.9 2.5 0.41 10.1 1.7 1.9 1 1 0 1 1 1 0 AAA domain Glyco_transf_8 PF01501.15 XP_011273421.1 - 4.7e-37 127.6 0.2 1.1e-36 126.4 0.1 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.11 XP_011273421.1 - 0.0031 17.3 0.0 0.0062 16.3 0.0 1.4 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase DUF89 PF01937.14 XP_011273421.1 - 0.013 14.3 1.1 0.013 14.3 0.8 2.0 2 1 0 2 2 2 0 Protein of unknown function DUF89 Mannosyl_trans3 PF11051.3 XP_011273421.1 - 0.013 14.8 0.1 0.013 14.8 0.1 2.0 2 0 0 2 2 2 0 Mannosyltransferase putative DUF2951 PF11166.3 XP_011273421.1 - 0.039 13.7 3.9 0.19 11.6 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) Ribosomal_S21e PF01249.13 XP_011273422.1 - 5.5e-40 135.1 0.0 6.1e-40 135.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e tRNA_U5-meth_tr PF05958.6 XP_011273423.1 - 1.7e-20 72.9 0.0 1.7e-19 69.7 0.0 2.1 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 XP_011273423.1 - 1.4e-11 44.2 0.5 3.6e-11 42.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain TRAM PF01938.15 XP_011273423.1 - 2e-10 40.3 0.0 3.8e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 TRAM domain PrmA PF06325.8 XP_011273423.1 - 1.7e-07 30.6 0.0 3.9e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 XP_011273423.1 - 4.4e-07 30.4 0.0 1.2e-06 29.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 XP_011273423.1 - 1.9e-06 27.3 0.0 4e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 XP_011273423.1 - 9.6e-06 25.6 0.0 1.8e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 XP_011273423.1 - 1.3e-05 24.6 1.2 2.4e-05 23.8 0.0 1.9 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_15 PF09445.5 XP_011273423.1 - 6.1e-05 22.6 0.0 0.00012 21.6 0.0 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.1 XP_011273423.1 - 0.00012 22.3 0.0 0.00028 21.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 XP_011273423.1 - 0.00016 21.3 0.0 0.00031 20.4 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_11 PF08241.7 XP_011273423.1 - 0.00044 20.6 0.0 0.0014 19.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 XP_011273423.1 - 0.00048 19.3 0.0 0.00089 18.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family TRM PF02005.11 XP_011273423.1 - 0.0022 17.0 0.1 0.033 13.1 0.0 2.2 2 0 0 2 2 2 1 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_4 PF02390.12 XP_011273423.1 - 0.0045 16.0 0.0 0.0045 16.0 0.0 2.3 2 0 0 2 2 2 1 Putative methyltransferase UPF0020 PF01170.13 XP_011273423.1 - 0.015 14.9 0.1 0.044 13.3 0.0 1.8 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 Methyltransf_12 PF08242.7 XP_011273423.1 - 0.06 13.8 0.1 0.06 13.8 0.1 2.6 4 1 0 4 4 1 0 Methyltransferase domain YjeF_N PF03853.10 XP_011273425.1 - 7e-28 97.3 0.0 1.1e-27 96.6 0.0 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.5 XP_011273425.1 - 0.012 16.1 1.6 0.012 16.1 1.1 2.5 2 0 0 2 2 2 0 FDF domain Arm PF00514.18 XP_011273426.1 - 9.1e-76 247.3 34.7 1.6e-12 46.7 0.2 11.4 11 1 1 12 12 12 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 XP_011273426.1 - 7.5e-26 90.2 14.4 1.7e-06 28.1 0.1 7.1 1 1 6 8 8 8 6 HEAT repeats HEAT_EZ PF13513.1 XP_011273426.1 - 2.8e-18 65.8 18.4 1.5e-06 28.4 0.7 8.4 8 1 1 9 9 9 5 HEAT-like repeat HEAT PF02985.17 XP_011273426.1 - 2.9e-17 61.1 29.8 0.00055 19.7 0.1 10.6 11 1 0 11 11 11 5 HEAT repeat Adaptin_N PF01602.15 XP_011273426.1 - 8.8e-15 54.0 18.3 6.8e-09 34.5 1.7 2.5 1 1 1 2 2 2 2 Adaptin N terminal region KAP PF05804.7 XP_011273426.1 - 2e-13 49.2 6.5 6.6e-08 30.9 0.9 2.2 1 1 1 2 2 2 2 Kinesin-associated protein (KAP) Arm_2 PF04826.8 XP_011273426.1 - 1.6e-10 40.5 14.4 1.6e-06 27.3 3.1 4.0 2 1 2 4 4 4 3 Armadillo-like RIX1 PF08167.7 XP_011273426.1 - 9.4e-06 25.4 2.5 0.037 13.7 0.2 3.7 2 2 0 3 3 3 1 rRNA processing/ribosome biogenesis Vac14_Fab1_bd PF12755.2 XP_011273426.1 - 0.00012 22.3 0.2 1.3 9.4 0.0 3.6 2 1 2 4 4 4 2 Vacuolar 14 Fab1-binding region DUF2454 PF10521.4 XP_011273426.1 - 0.00013 21.1 1.4 0.08 11.9 0.0 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF2454) V-ATPase_H_C PF11698.3 XP_011273426.1 - 0.0093 15.8 5.7 2.3 8.1 0.0 5.2 2 2 5 7 7 7 1 V-ATPase subunit H HEAT_PBS PF03130.11 XP_011273426.1 - 0.022 15.1 7.4 1e+02 3.8 0.0 6.7 7 0 0 7 7 6 0 PBS lyase HEAT-like repeat DUF1981 PF09324.5 XP_011273426.1 - 0.03 13.8 0.2 20 4.7 0.0 4.1 4 1 1 5 5 5 0 Domain of unknown function (DUF1981) XPC-binding PF09280.6 XP_011273426.1 - 0.62 9.5 6.4 13 5.3 0.1 4.0 4 0 0 4 4 4 0 XPC-binding domain WD40 PF00400.27 XP_011273427.1 - 6.5e-61 200.1 11.7 4e-11 42.3 0.1 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 XP_011273427.1 - 2.8e-51 173.3 0.1 7e-51 172.0 0.1 1.7 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit LisH PF08513.6 XP_011273427.1 - 2.6e-05 23.7 0.1 6.5e-05 22.5 0.1 1.7 1 0 0 1 1 1 1 LisH eIF2A PF08662.6 XP_011273427.1 - 0.00036 20.3 0.0 0.049 13.3 0.0 2.9 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 XP_011273427.1 - 0.0014 16.9 0.2 0.93 7.5 0.0 3.3 2 1 0 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 XP_011273427.1 - 0.032 13.0 0.4 0.75 8.4 0.1 2.7 1 1 2 3 3 3 0 Nup133 N terminal like PD40 PF07676.7 XP_011273427.1 - 0.043 13.5 0.1 9.1 6.0 0.0 2.8 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat TFIIA PF03153.8 XP_011273427.1 - 1.5 8.6 18.6 2.5 7.9 12.9 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Orexin_rec2 PF03827.8 XP_011273428.1 - 0.041 13.9 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 Orexin receptor type 2 PGI PF00342.14 XP_011273429.1 - 6.7e-220 730.5 1.5 7.9e-220 730.3 1.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase DUF2794 PF10984.3 XP_011273429.1 - 0.023 14.5 0.1 0.6 9.9 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2794) WD40 PF00400.27 XP_011273430.1 - 1.6e-23 81.6 13.6 7.7e-07 28.7 0.0 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 XP_011273430.1 - 0.0002 21.1 0.0 0.00044 20.0 0.0 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex SdiA-regulated PF06977.6 XP_011273430.1 - 0.07 12.0 0.0 5 5.9 0.0 2.7 2 1 0 2 2 2 0 SdiA-regulated Mt_ATP-synt_B PF05405.9 XP_011273431.1 - 2.8e-58 195.9 11.3 3.3e-58 195.7 7.8 1.0 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) SRX PF09201.5 XP_011273431.1 - 0.0025 17.4 2.0 0.0035 17.0 1.4 1.2 1 0 0 1 1 1 1 SRX Wbp11 PF09429.5 XP_011273432.1 - 1.2e-05 25.2 15.5 1.2e-05 25.2 10.7 2.3 2 1 1 3 3 3 1 WW domain binding protein 11 Med8 PF10232.4 XP_011273433.1 - 6.1e-25 88.0 7.5 8.8e-24 84.2 2.8 3.2 1 1 1 2 2 2 1 Mediator of RNA polymerase II transcription complex subunit 8 Mito_carr PF00153.22 XP_011273434.1 - 2.8e-79 260.9 1.4 4.1e-28 96.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L21e PF01157.13 XP_011273435.1 - 3.1e-38 129.5 3.4 4.9e-38 128.9 2.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L21e Ribosomal_S4 PF00163.14 XP_011273436.1 - 8.4e-24 83.7 1.0 1.5e-23 82.9 0.7 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 XP_011273436.1 - 4.9e-13 48.2 0.5 4.9e-13 48.2 0.3 2.3 2 0 0 2 2 2 1 S4 domain DUF3535 PF12054.3 XP_011273437.1 - 9.3e-133 443.0 1.9 1.2e-130 436.1 0.2 3.3 3 0 0 3 3 3 2 Domain of unknown function (DUF3535) SNF2_N PF00176.18 XP_011273437.1 - 3.5e-77 259.1 0.4 1.8e-76 256.7 0.0 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain HEAT PF02985.17 XP_011273437.1 - 6.8e-14 50.6 10.6 0.3 11.2 0.0 10.1 9 0 0 9 9 9 3 HEAT repeat Helicase_C PF00271.26 XP_011273437.1 - 1.4e-13 50.5 0.0 3.5e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Vac14_Fab1_bd PF12755.2 XP_011273437.1 - 2.9e-12 46.8 1.2 0.0084 16.4 0.0 5.5 5 0 0 5 5 5 3 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.1 XP_011273437.1 - 5.6e-10 39.3 6.7 0.027 14.7 0.0 7.2 5 3 2 7 7 7 2 HEAT repeats HEAT_EZ PF13513.1 XP_011273437.1 - 4e-07 30.3 20.6 0.19 12.2 0.8 8.9 9 0 0 9 9 9 2 HEAT-like repeat DUF1546 PF07571.8 XP_011273437.1 - 0.013 15.6 0.0 18 5.4 0.0 4.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1546) UPF0118 PF01594.11 XP_011273437.1 - 3.3 6.6 3.9 8.5 5.2 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function DUF20 HEAT_PBS PF03130.11 XP_011273437.1 - 4.7 7.9 5.8 39 5.1 0.0 4.8 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat cwf18 PF08315.7 XP_011273438.1 - 3.5e-07 30.7 8.0 8.5e-07 29.4 5.6 1.6 1 1 0 1 1 1 1 cwf18 pre-mRNA splicing factor Mt_ATP-synt_B PF05405.9 XP_011273438.1 - 0.061 12.7 4.3 0.13 11.7 0.7 2.1 1 1 1 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) FBP PF07299.6 XP_011273438.1 - 0.066 12.5 3.1 0.081 12.2 2.2 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein (FBP) HTH_40 PF14493.1 XP_011273438.1 - 0.12 12.6 1.8 0.4 10.9 0.1 2.2 1 1 1 2 2 2 0 Helix-turn-helix domain Ubiq_cyt_C_chap PF03981.7 XP_011273438.1 - 0.13 12.1 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Ubiquinol-cytochrome C chaperone MbeB_N PF04837.7 XP_011273438.1 - 0.45 10.6 2.6 2 8.5 0.1 2.6 2 1 0 2 2 2 0 MbeB-like, N-term conserved region Spectrin PF00435.16 XP_011273438.1 - 1.7 8.9 5.3 3.5 7.9 0.3 2.2 1 1 1 2 2 2 0 Spectrin repeat UPF0016 PF01169.14 XP_011273439.1 - 8.4e-40 134.7 24.8 3e-21 75.3 5.4 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 TerC PF03741.11 XP_011273439.1 - 0.0036 16.7 0.9 0.0036 16.7 0.6 2.2 2 0 0 2 2 2 1 Integral membrane protein TerC family Complex1_51K PF01512.12 XP_011273440.1 - 4.1e-47 159.6 0.0 6.6e-47 159.0 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 XP_011273440.1 - 1.3e-17 62.6 0.1 2.7e-17 61.6 0.1 1.6 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 XP_011273440.1 - 4.7e-08 32.7 0.0 1.1e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 SLBB domain AAA PF00004.24 XP_011273441.1 - 7.4e-33 113.5 0.0 1.4e-32 112.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 XP_011273441.1 - 6.9e-08 32.7 0.2 2.8e-07 30.7 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 XP_011273441.1 - 1.8e-06 28.7 0.0 6.2e-06 27.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 XP_011273441.1 - 2.6e-06 27.3 0.2 2.6e-06 27.3 0.2 2.4 3 1 0 3 3 1 1 AAA domain AAA_16 PF13191.1 XP_011273441.1 - 4.4e-06 26.7 0.1 1.9e-05 24.7 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_31 PF13614.1 XP_011273441.1 - 5.9e-06 26.2 2.0 6e-06 26.2 0.2 2.0 2 1 0 2 2 1 1 AAA domain TIP49 PF06068.8 XP_011273441.1 - 9.3e-06 24.5 0.0 2.5e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 TIP49 C-terminus AAA_24 PF13479.1 XP_011273441.1 - 5.4e-05 22.8 0.3 0.00027 20.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 XP_011273441.1 - 8.3e-05 22.3 4.0 0.006 16.3 2.7 3.0 1 1 0 1 1 1 1 Archaeal ATPase AAA_18 PF13238.1 XP_011273441.1 - 0.00014 22.1 0.2 0.00014 22.1 0.2 3.3 2 2 1 3 3 2 1 AAA domain UPF0079 PF02367.12 XP_011273441.1 - 0.00014 21.4 0.0 0.00038 20.0 0.0 1.7 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 XP_011273441.1 - 0.00043 19.9 0.6 0.0015 18.2 0.4 2.0 1 1 0 1 1 1 1 NACHT domain Bac_DnaA PF00308.13 XP_011273441.1 - 0.0005 19.7 0.3 0.0042 16.7 0.2 2.2 1 1 0 1 1 1 1 Bacterial dnaA protein RNA_helicase PF00910.17 XP_011273441.1 - 0.00054 20.1 0.3 0.0027 17.8 0.0 2.3 2 0 0 2 2 2 1 RNA helicase AAA_5 PF07728.9 XP_011273441.1 - 0.00069 19.3 1.8 0.081 12.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 XP_011273441.1 - 0.00069 19.9 0.1 0.0021 18.3 0.0 1.9 2 0 0 2 2 1 1 ABC transporter PduV-EutP PF10662.4 XP_011273441.1 - 0.0014 18.1 0.0 0.0035 16.8 0.0 1.6 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.8 XP_011273441.1 - 0.0015 17.4 0.7 0.0064 15.4 0.5 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_2 PF07724.9 XP_011273441.1 - 0.0029 17.5 0.0 0.012 15.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 XP_011273441.1 - 0.003 17.4 0.0 0.0058 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 XP_011273441.1 - 0.0042 16.3 0.3 0.0091 15.1 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 RuvB_N PF05496.7 XP_011273441.1 - 0.0047 16.0 0.1 0.014 14.5 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus MobB PF03205.9 XP_011273441.1 - 0.0058 16.3 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 XP_011273441.1 - 0.0058 15.5 0.0 0.012 14.5 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_29 PF13555.1 XP_011273441.1 - 0.016 14.7 0.0 0.035 13.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SE PF00437.15 XP_011273441.1 - 0.017 14.0 0.0 0.035 13.0 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein IstB_IS21 PF01695.12 XP_011273441.1 - 0.018 14.4 0.0 0.045 13.1 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 XP_011273441.1 - 0.029 13.7 0.2 0.083 12.2 0.1 1.7 1 1 1 2 2 2 0 AAA domain SRP54 PF00448.17 XP_011273441.1 - 0.04 13.3 0.1 0.085 12.2 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Sigma54_activat PF00158.21 XP_011273441.1 - 0.054 12.9 0.1 0.14 11.6 0.0 1.7 2 0 0 2 2 1 0 Sigma-54 interaction domain Mg_chelatase PF01078.16 XP_011273441.1 - 0.073 12.2 0.0 0.23 10.5 0.0 1.8 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI SMC_N PF02463.14 XP_011273441.1 - 0.094 11.9 0.1 0.094 11.9 0.1 2.0 3 0 0 3 3 2 0 RecF/RecN/SMC N terminal domain AAA_19 PF13245.1 XP_011273441.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain Zot PF05707.7 XP_011273441.1 - 0.12 11.8 0.0 0.25 10.7 0.0 1.6 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) Zeta_toxin PF06414.7 XP_011273441.1 - 0.12 11.4 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.1 XP_011273441.1 - 0.14 12.1 0.1 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Catalase PF00199.14 XP_011273442.1 - 3.3e-176 585.6 0.1 4.5e-176 585.1 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 XP_011273442.1 - 1.2e-09 37.8 0.6 5.4e-09 35.7 0.0 2.4 3 0 0 3 3 3 1 Catalase-related immune-responsive Nucleoporin_C PF03177.9 XP_011273443.1 - 3.5e-103 346.1 24.5 4.8e-103 345.7 17.0 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 XP_011273443.1 - 4.2e-96 322.2 10.3 7.1e-96 321.5 7.2 1.4 1 0 0 1 1 1 1 Nup133 N terminal like AsmA_1 PF13109.1 XP_011273444.1 - 0.048 12.9 0.2 0.079 12.2 0.1 1.3 1 0 0 1 1 1 0 AsmA-like C-terminal region WD40 PF00400.27 XP_011273446.1 - 2.5e-24 84.1 1.4 7.4e-05 22.4 0.0 5.1 6 0 0 6 6 6 4 WD domain, G-beta repeat PQQ_2 PF13360.1 XP_011273446.1 - 0.023 14.1 0.1 0.054 12.9 0.1 1.6 2 0 0 2 2 2 0 PQQ-like domain Voltage_CLC PF00654.15 XP_011273447.1 - 7.4e-83 278.4 20.8 7.4e-83 278.4 14.4 1.6 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 XP_011273447.1 - 5.7e-06 26.0 0.1 0.079 12.7 0.0 3.0 3 0 0 3 3 3 2 CBS domain LisH PF08513.6 XP_011273448.1 - 5.8e-07 29.0 0.0 1.2e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 LisH ALG3 PF05208.8 XP_011273449.1 - 1.7e-116 389.4 27.6 2.1e-116 389.1 19.1 1.0 1 0 0 1 1 1 1 ALG3 protein HEAT_EZ PF13513.1 XP_011273450.1 - 6.6e-23 80.5 4.7 5.7e-05 23.4 0.1 10.2 8 2 2 10 10 10 5 HEAT-like repeat HEAT_2 PF13646.1 XP_011273450.1 - 7.9e-15 54.9 9.9 0.0029 17.8 0.2 8.4 6 2 3 9 9 9 6 HEAT repeats HEAT PF02985.17 XP_011273450.1 - 2.6e-11 42.6 8.8 0.18 11.9 0.1 10.1 14 0 0 14 14 12 3 HEAT repeat IBN_N PF03810.14 XP_011273450.1 - 2.1e-09 37.1 7.9 3.7e-08 33.1 0.2 4.4 4 0 0 4 4 4 1 Importin-beta N-terminal domain CLASP_N PF12348.3 XP_011273450.1 - 7.5e-09 35.2 8.1 0.019 14.3 0.1 6.4 5 2 2 7 7 7 3 CLASP N terminal Vac14_Fab1_bd PF12755.2 XP_011273450.1 - 3.8e-08 33.6 8.3 0.014 15.7 0.2 7.2 6 1 1 7 7 7 2 Vacuolar 14 Fab1-binding region RIX1 PF08167.7 XP_011273450.1 - 9.9e-07 28.5 1.0 0.038 13.6 0.0 4.9 4 1 1 5 5 5 3 rRNA processing/ribosome biogenesis Ipi1_N PF12333.3 XP_011273450.1 - 0.0086 16.0 6.7 2.1 8.3 0.0 5.8 7 1 1 8 8 7 1 Rix1 complex component involved in 60S ribosome maturation DUF1981 PF09324.5 XP_011273450.1 - 0.015 14.8 0.2 3.8 7.0 0.0 4.8 5 0 0 5 5 5 0 Domain of unknown function (DUF1981) Cnd1 PF12717.2 XP_011273450.1 - 0.019 14.7 16.9 1.6 8.5 0.3 6.9 4 3 2 8 8 8 0 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.11 XP_011273450.1 - 0.37 11.3 5.0 15 6.4 0.0 5.4 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat Ank_2 PF12796.2 XP_011273451.1 - 3.7e-12 46.4 0.6 0.00016 21.9 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 XP_011273451.1 - 8.7e-12 45.2 1.3 4.2e-06 27.1 0.0 3.9 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.25 XP_011273451.1 - 3.4e-11 42.3 0.0 8.6e-06 25.3 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 XP_011273451.1 - 1.9e-07 30.6 0.0 0.018 15.2 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 XP_011273451.1 - 2e-07 30.9 0.1 0.00072 19.7 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) KilA-N PF04383.8 XP_011273451.1 - 2.3e-06 27.1 3.1 1.1e-05 24.9 0.1 3.5 2 2 0 2 2 2 1 KilA-N domain Med15 PF09606.5 XP_011273451.1 - 0.024 12.8 47.3 0.033 12.3 32.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 XP_011273451.1 - 1.6 6.8 55.0 2.4 6.2 38.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 LSM PF01423.17 XP_011273452.1 - 4.7e-10 38.8 0.6 7.8e-10 38.1 0.4 1.5 1 1 0 1 1 1 1 LSM domain SM-ATX PF14438.1 XP_011273452.1 - 0.011 15.6 0.0 0.027 14.3 0.0 1.7 1 0 0 1 1 1 0 Ataxin 2 SM domain RelB PF04221.7 XP_011273452.1 - 0.17 11.6 2.3 0.9 9.3 1.4 2.4 1 1 1 2 2 2 0 RelB antitoxin EMP70 PF02990.11 XP_011273453.1 - 6e-160 533.1 9.1 7.2e-160 532.8 6.3 1.0 1 0 0 1 1 1 1 Endomembrane protein 70 TPR_1 PF00515.23 XP_011273454.1 - 9.8e-41 135.7 13.8 4.8e-07 29.1 0.0 10.0 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_11 PF13414.1 XP_011273454.1 - 4.4e-40 135.1 12.9 3.7e-10 39.2 0.0 7.4 5 1 2 7 7 7 6 TPR repeat TPR_2 PF07719.12 XP_011273454.1 - 1.8e-39 130.4 11.9 4.6e-05 23.0 0.0 9.6 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_8 PF13181.1 XP_011273454.1 - 3.8e-27 91.9 5.7 0.0017 18.0 0.0 9.0 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_12 PF13424.1 XP_011273454.1 - 7e-25 86.7 13.8 9.9e-05 22.2 0.0 7.3 6 1 1 7 7 7 6 Tetratricopeptide repeat Apc3 PF12895.2 XP_011273454.1 - 8.2e-25 86.7 15.1 9.7e-15 54.4 0.4 5.9 3 1 2 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 XP_011273454.1 - 1.3e-23 83.0 6.0 1.5e-05 25.5 0.9 7.4 6 1 2 8 8 7 4 Tetratricopeptide repeat TPR_17 PF13431.1 XP_011273454.1 - 3.4e-16 58.0 10.2 0.038 14.2 0.0 9.9 9 1 1 10 10 10 5 Tetratricopeptide repeat TPR_14 PF13428.1 XP_011273454.1 - 3.6e-15 55.0 1.4 0.066 13.8 0.0 7.9 5 1 4 9 9 7 3 Tetratricopeptide repeat TPR_7 PF13176.1 XP_011273454.1 - 1.3e-12 46.4 1.2 0.36 10.7 0.0 6.8 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.1 XP_011273454.1 - 2.2e-11 43.9 6.1 0.22 11.8 2.7 6.0 5 1 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 XP_011273454.1 - 3.3e-09 36.5 7.9 5.6 7.6 0.0 7.8 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_9 PF13371.1 XP_011273454.1 - 2.3e-08 33.7 2.4 0.028 14.2 0.0 4.3 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_10 PF13374.1 XP_011273454.1 - 0.011 15.6 1.7 16 5.5 0.1 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat Sel1 PF08238.7 XP_011273454.1 - 0.011 16.3 7.5 37 5.1 0.0 6.1 6 0 0 6 6 6 0 Sel1 repeat Sp100 PF03172.8 XP_011273454.1 - 0.021 14.7 0.1 3.9 7.5 0.0 2.7 2 0 0 2 2 2 0 Sp100 domain Fungal_trans PF04082.13 XP_011273456.1 - 2e-14 53.0 0.6 2e-14 53.0 0.4 2.2 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 XP_011273456.1 - 2.1e-07 30.7 9.4 5.5e-07 29.3 6.5 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LUC7 PF03194.10 XP_011273457.1 - 6.9e-74 248.5 10.2 7.8e-74 248.3 7.1 1.0 1 0 0 1 1 1 1 LUC7 N_terminus Ins_P5_2-kin PF06090.7 XP_011273457.1 - 0.0054 15.8 1.2 0.0068 15.4 0.8 1.2 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase APG6 PF04111.7 XP_011273457.1 - 0.13 11.3 7.4 0.2 10.6 5.1 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Med15_fungi PF05397.7 XP_011273457.1 - 0.29 11.1 4.0 0.16 11.9 0.9 1.8 2 1 0 2 2 2 0 Mediator complex subunit 15 Synaptobrevin PF00957.16 XP_011273457.1 - 0.4 10.3 4.2 0.84 9.2 1.8 2.2 1 1 1 2 2 2 0 Synaptobrevin Peptidase_S24 PF00717.18 XP_011273458.1 - 3.9e-08 32.8 0.1 1.1e-07 31.3 0.0 1.8 2 1 0 2 2 2 1 Peptidase S24-like Peptidase_S26 PF10502.4 XP_011273458.1 - 0.038 13.5 0.0 0.079 12.4 0.0 1.6 1 1 0 1 1 1 0 Signal peptidase, peptidase S26 adh_short PF00106.20 XP_011273459.1 - 1.3e-23 83.7 0.0 1.7e-23 83.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 XP_011273459.1 - 8.1e-11 41.9 0.0 1.4e-10 41.1 0.0 1.3 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 XP_011273459.1 - 4.2e-06 25.6 0.4 5.2e-06 25.3 0.3 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 XP_011273459.1 - 8.8e-06 25.8 0.0 1.1e-05 25.5 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 XP_011273459.1 - 9e-06 25.6 0.0 1.1e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 XP_011273459.1 - 0.0008 18.3 0.1 0.0011 17.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 XP_011273459.1 - 0.004 16.6 0.0 0.0052 16.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 XP_011273459.1 - 0.053 13.5 0.1 0.082 12.9 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain DPBB_1 PF03330.13 XP_011273459.1 - 0.12 12.3 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Rare lipoprotein A (RlpA)-like double-psi beta-barrel DUF1762 PF08574.5 XP_011273460.1 - 3.6e-11 43.3 5.9 3.6e-11 43.3 4.1 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF1762) Pox_RNA_Pol_19 PF05320.7 XP_011273460.1 - 4.4 7.0 15.3 51 3.5 0.0 2.6 1 1 2 3 3 3 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit CDC45 PF02724.9 XP_011273460.1 - 7.9 4.3 12.9 9.7 4.0 9.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Ribosomal_L6 PF00347.18 XP_011273461.1 - 3.1e-31 107.7 9.3 2e-17 63.4 1.8 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 YbbR PF07949.7 XP_011273461.1 - 0.0091 16.0 1.2 0.25 11.4 0.1 2.6 1 1 1 2 2 2 1 YbbR-like protein PNK3P PF08645.6 XP_011273462.1 - 6.6e-53 178.3 0.5 1e-52 177.7 0.4 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase ComK PF06338.6 XP_011273462.1 - 0.052 12.9 0.3 0.052 12.9 0.2 2.0 2 0 0 2 2 2 0 ComK protein HAD PF12710.2 XP_011273462.1 - 0.072 13.2 0.0 0.14 12.3 0.0 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 XP_011273462.1 - 0.13 12.4 0.2 8.1 6.6 0.0 2.9 2 1 1 3 3 3 0 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 XP_011273462.1 - 0.32 10.5 6.1 1 8.8 0.2 2.7 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase zf-C2H2_jaz PF12171.3 XP_011273463.1 - 1.2e-07 31.6 0.1 2.4e-07 30.7 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 XP_011273463.1 - 6.2e-06 26.2 0.2 1.1e-05 25.3 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type DUF1777 PF08648.7 XP_011273463.1 - 0.0017 18.1 8.2 0.0017 18.1 5.7 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1777) zf-DBF PF07535.7 XP_011273463.1 - 0.014 15.0 0.2 0.03 13.9 0.1 1.5 1 0 0 1 1 1 0 DBF zinc finger zf-C2H2_2 PF12756.2 XP_011273463.1 - 0.051 13.6 0.1 0.097 12.7 0.0 1.6 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 XP_011273463.1 - 0.12 12.7 0.9 0.24 11.8 0.3 1.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type NinE PF05322.6 XP_011273463.1 - 0.45 10.3 3.9 0.47 10.2 1.1 2.2 2 1 0 2 2 2 0 NINE Protein DUF4584 PF15223.1 XP_011273463.1 - 2.8 7.1 9.9 1.8 7.7 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4584) DUF3513 PF12026.3 XP_011273463.1 - 5.6 6.4 9.4 8.6 5.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3513) ADK PF00406.17 XP_011273464.1 - 0.006 16.4 0.2 0.013 15.3 0.1 1.7 1 0 0 1 1 1 1 Adenylate kinase Ribosomal_S8 PF00410.14 XP_011273465.1 - 1.7e-15 56.9 0.0 4.8e-15 55.5 0.0 1.7 1 1 0 1 1 1 1 Ribosomal protein S8 WD40 PF00400.27 XP_011273467.1 - 6.5e-29 98.7 0.0 7.3e-09 35.1 0.1 6.2 5 1 0 5 5 5 5 WD domain, G-beta repeat PQQ_2 PF13360.1 XP_011273467.1 - 0.00041 19.8 0.0 0.00094 18.7 0.0 1.7 1 1 0 1 1 1 1 PQQ-like domain Coatomer_WDAD PF04053.9 XP_011273467.1 - 0.038 12.8 0.1 0.081 11.7 0.1 1.5 1 1 0 1 1 1 0 Coatomer WD associated region Nucleoporin_N PF08801.6 XP_011273467.1 - 0.041 12.6 0.3 0.93 8.1 0.0 2.1 2 0 0 2 2 2 0 Nup133 N terminal like RNA_pol_Rpb4 PF03874.11 XP_011273468.1 - 1.5e-27 95.8 2.3 2.5e-27 95.1 1.6 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb4 Pkinase PF00069.20 XP_011273469.1 - 2.7e-52 177.5 0.0 1.3e-51 175.2 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011273469.1 - 2.6e-19 69.2 0.0 4.7e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 XP_011273469.1 - 0.001 18.8 0.0 0.0021 17.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 XP_011273469.1 - 0.017 14.4 0.0 0.036 13.4 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Tim17 PF02466.14 XP_011273470.1 - 3.8e-31 107.7 3.8 4.5e-31 107.5 2.6 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Mannosyl_trans3 PF11051.3 XP_011273471.1 - 5.2e-86 288.3 0.6 2.8e-85 285.9 0.0 2.0 2 0 0 2 2 2 1 Mannosyltransferase putative Pyr_redox_2 PF07992.9 XP_011273472.1 - 1.8e-28 99.8 1.2 4.6e-19 69.1 0.0 3.2 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 XP_011273472.1 - 5.7e-14 52.2 0.0 2.3e-11 43.9 0.1 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 XP_011273472.1 - 2.8e-09 37.3 0.1 4.4e-05 23.6 0.1 3.6 3 1 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Bac_luciferase PF00296.15 XP_011273473.1 - 8.7e-48 163.0 0.0 1.3e-47 162.4 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase SSF PF00474.12 XP_011273474.1 - 1.1e-16 60.5 26.8 1.7e-16 59.9 18.6 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family BK_channel_a PF03493.13 XP_011273474.1 - 0.021 14.7 0.1 1.1 9.2 0.0 2.9 3 0 0 3 3 3 0 Calcium-activated BK potassium channel alpha subunit SSF PF00474.12 XP_011273475.1 - 1.2e-15 57.1 25.5 1.8e-15 56.5 17.7 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family Arginase PF00491.16 XP_011273476.1 - 1.8e-73 247.2 0.0 2.1e-73 247.0 0.0 1.0 1 0 0 1 1 1 1 Arginase family RRM_1 PF00076.17 XP_011273477.1 - 6.4e-06 25.7 0.1 1.4e-05 24.5 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 XP_011273477.1 - 0.00031 20.6 0.0 0.00099 19.0 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FadA PF09403.5 XP_011273477.1 - 0.4 10.6 3.4 0.31 11.0 1.0 1.8 2 0 0 2 2 2 0 Adhesion protein FadA GDPD PF03009.12 XP_011273478.1 - 1.4e-76 257.3 0.0 2.7e-76 256.4 0.0 1.5 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 XP_011273478.1 - 1.9e-22 79.3 0.0 4.3e-09 36.5 0.0 4.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 XP_011273478.1 - 7.9e-20 69.6 0.2 0.17 11.7 0.0 7.2 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.1 XP_011273478.1 - 1.4e-18 66.8 0.0 2.2e-05 24.8 0.0 4.7 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 XP_011273478.1 - 7.8e-15 53.5 0.2 1.2 9.6 0.0 7.4 7 0 0 7 7 7 4 Ankyrin repeat SPX PF03105.14 XP_011273478.1 - 2.2e-14 53.9 9.0 2.3e-09 37.4 0.0 3.8 3 2 2 5 5 5 2 SPX domain Ank_5 PF13857.1 XP_011273478.1 - 6.9e-09 35.6 0.0 0.82 10.0 0.0 4.9 2 1 4 6 6 6 4 Ankyrin repeats (many copies) GDPD_2 PF13653.1 XP_011273478.1 - 0.0037 17.4 0.7 0.041 14.0 0.1 2.6 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family ABC1 PF03109.11 XP_011273479.1 - 2.5e-21 75.8 0.1 5.1e-13 49.0 0.0 2.8 3 0 0 3 3 3 2 ABC1 family RIO1 PF01163.17 XP_011273479.1 - 0.00012 21.5 0.2 0.0036 16.6 0.0 2.2 2 0 0 2 2 2 1 RIO1 family Pkinase_Tyr PF07714.12 XP_011273479.1 - 0.005 15.9 0.0 0.036 13.1 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 XP_011273479.1 - 0.019 14.0 1.8 0.073 12.2 1.2 1.9 1 1 0 1 1 1 0 Protein kinase domain PDH PF02153.12 XP_011273480.1 - 1.2e-15 57.0 0.1 1.6e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.10 XP_011273480.1 - 6.4e-06 26.1 0.0 1.2e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 XP_011273480.1 - 6.9e-06 26.4 0.1 2.3e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 XP_011273480.1 - 0.00012 21.3 0.0 0.00025 20.2 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 XP_011273480.1 - 0.00028 20.3 0.0 0.00044 19.7 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 XP_011273480.1 - 0.003 17.2 0.1 0.017 14.7 0.0 2.0 1 1 1 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rossmann-like PF10727.4 XP_011273480.1 - 0.0089 15.7 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 Rossmann-like domain UDPG_MGDP_dh_N PF03721.9 XP_011273480.1 - 0.041 13.2 0.0 0.078 12.3 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.13 XP_011273480.1 - 0.044 13.7 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain IlvN PF07991.7 XP_011273480.1 - 0.056 12.8 0.0 0.094 12.0 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Abhydro_lipase PF04083.11 XP_011273481.1 - 3.5e-17 61.5 0.0 5.8e-17 60.7 0.0 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 XP_011273481.1 - 0.0004 20.3 0.0 0.00048 20.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family chaperone_DMP PF10448.4 XP_011273482.1 - 1.2e-16 60.8 3.9 1.4e-16 60.6 2.7 1.1 1 0 0 1 1 1 1 20S proteasome chaperone SBDS_C PF09377.5 XP_011273483.1 - 2.5e-36 124.1 2.0 2.5e-36 124.1 1.4 1.5 2 0 0 2 2 2 1 SBDS protein C-terminal domain SBDS PF01172.13 XP_011273483.1 - 3.1e-32 110.2 1.4 5.2e-32 109.5 1.0 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein HlyIII PF03006.15 XP_011273484.1 - 6.7e-56 189.1 15.4 8.3e-56 188.8 10.7 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF1477 PF07346.6 XP_011273484.1 - 0.0082 16.1 0.1 0.018 15.0 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1477) DUF962 PF06127.6 XP_011273484.1 - 0.014 15.2 0.0 0.07 13.0 0.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF962) Fasciclin PF02469.17 XP_011273485.1 - 3.7e-22 78.6 14.3 2.6e-09 37.1 0.6 5.5 4 2 1 5 5 5 4 Fasciclin domain DUF485 PF04341.7 XP_011273485.1 - 0.19 11.4 0.9 0.4 10.4 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF485 RRM_6 PF14259.1 XP_011273486.1 - 1.3e-14 53.9 0.0 2.1e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 XP_011273486.1 - 3e-14 52.3 0.0 4.9e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 XP_011273486.1 - 4.2e-07 29.7 0.0 7e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Aa_trans PF01490.13 XP_011273487.1 - 5.6e-65 219.4 33.6 6.6e-65 219.1 23.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2107 PF09880.4 XP_011273487.1 - 0.08 12.8 0.3 0.08 12.8 0.2 3.1 3 0 0 3 3 3 0 Predicted membrane protein (DUF2107) Sugar_tr PF00083.19 XP_011273488.1 - 1.3e-98 330.5 24.9 1.6e-98 330.2 17.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 XP_011273488.1 - 5.1e-25 87.9 20.1 1.9e-23 82.7 8.9 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 XP_011273488.1 - 0.00066 18.1 28.7 0.0035 15.8 7.0 3.5 3 1 0 3 3 3 2 MFS/sugar transport protein VWA_2 PF13519.1 XP_011273489.1 - 4.9e-07 30.0 0.0 7.1e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain UIM PF02809.15 XP_011273489.1 - 0.0013 18.1 0.8 0.003 16.9 0.6 1.6 1 0 0 1 1 1 1 Ubiquitin interaction motif Ssl1 PF04056.9 XP_011273489.1 - 0.014 14.9 0.0 0.02 14.4 0.0 1.2 1 0 0 1 1 1 0 Ssl1-like Serine_rich PF08824.5 XP_011273489.1 - 0.089 12.5 0.1 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Serine rich protein interaction domain DUF3608 PF12257.3 XP_011273490.1 - 7.9e-124 412.1 3.0 1.4e-123 411.2 2.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 XP_011273490.1 - 5.6e-28 96.4 0.2 1.3e-27 95.3 0.1 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) MFS_1 PF07690.11 XP_011273491.1 - 1.1e-40 139.4 43.3 1.6e-34 119.2 15.7 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MerC PF03203.9 XP_011273491.1 - 8.8 6.7 11.8 0.19 12.0 1.8 2.7 3 0 0 3 3 3 0 MerC mercury resistance protein HECT_2 PF09814.4 XP_011273492.1 - 1.9e-62 211.0 0.8 2.4e-62 210.7 0.5 1.1 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Homoserine_dh PF00742.14 XP_011273492.1 - 1.2e-52 178.2 0.0 2.1e-52 177.4 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 XP_011273492.1 - 3.8e-15 56.3 0.0 7.5e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DUF2424 PF10340.4 XP_011273494.1 - 0.00081 18.1 0.1 0.0012 17.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_3 PF07859.8 XP_011273494.1 - 0.0043 16.6 0.1 0.028 14.0 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 XP_011273494.1 - 0.031 14.0 0.0 0.038 13.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.20 XP_011273494.1 - 0.097 12.2 0.4 0.44 10.1 0.1 2.0 2 1 0 2 2 2 0 Lipase (class 3) Abhydrolase_5 PF12695.2 XP_011273495.1 - 0.0018 18.0 0.0 0.0023 17.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 XP_011273495.1 - 0.006 16.4 0.0 0.0091 15.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 XP_011273495.1 - 0.011 14.3 0.3 0.11 11.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2424) Abhydrolase_3 PF07859.8 XP_011273495.1 - 0.018 14.6 0.0 4.6 6.7 0.0 2.3 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 XP_011273495.1 - 0.042 13.3 0.0 0.09 12.3 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Bac_luciferase PF00296.15 XP_011273496.1 - 3.9e-47 160.8 0.0 5.2e-47 160.4 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Abhydrolase_3 PF07859.8 XP_011273497.1 - 0.0013 18.2 0.0 0.003 17.1 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 XP_011273497.1 - 0.003 17.4 0.0 0.0042 16.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 XP_011273497.1 - 0.02 14.4 0.0 0.44 10.0 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 XP_011273497.1 - 0.028 14.1 0.0 0.03 14.0 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2305 PF10230.4 XP_011273497.1 - 0.028 13.8 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) DUF2424 PF10340.4 XP_011273497.1 - 0.03 12.9 0.2 0.065 11.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) PGAP1 PF07819.8 XP_011273498.1 - 3e-07 30.2 0.0 4e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_3 PF07859.8 XP_011273498.1 - 4.4e-05 23.1 0.0 9.3e-05 22.0 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 XP_011273498.1 - 0.00029 20.6 0.0 0.00038 20.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 XP_011273498.1 - 0.0032 17.0 0.1 0.0058 16.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 XP_011273498.1 - 0.0033 17.3 0.0 0.0056 16.5 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 XP_011273498.1 - 0.044 12.8 0.0 0.084 11.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) UvdE PF03851.9 XP_011273498.1 - 0.048 12.6 0.1 0.17 10.8 0.0 1.8 2 0 0 2 2 2 0 UV-endonuclease UvdE Abhydrolase_3 PF07859.8 XP_011273499.1 - 0.00026 20.6 0.0 0.00066 19.3 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 XP_011273499.1 - 0.0011 17.6 0.7 0.14 10.7 0.4 2.3 2 1 0 2 2 2 2 Protein of unknown function (DUF2424) DUF2305 PF10230.4 XP_011273499.1 - 0.0038 16.6 0.0 0.0068 15.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) PGAP1 PF07819.8 XP_011273499.1 - 0.004 16.7 0.1 0.0098 15.5 0.0 1.6 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 XP_011273499.1 - 0.01 15.6 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 XP_011273499.1 - 0.011 15.3 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 XP_011273499.1 - 0.024 14.5 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF915 PF06028.6 XP_011273499.1 - 0.033 13.2 0.3 0.38 9.8 0.1 2.2 1 1 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_9 PF10081.4 XP_011273499.1 - 0.038 12.7 0.0 0.054 12.1 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta-hydrolase family Lipase_3 PF01764.20 XP_011273499.1 - 0.04 13.5 0.0 0.065 12.8 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) MFS_1 PF07690.11 XP_011273500.1 - 1.9e-16 59.7 16.2 4.8e-08 32.1 4.6 2.8 3 0 0 3 3 3 2 Major Facilitator Superfamily DUF996 PF06195.8 XP_011273500.1 - 0.082 12.8 0.4 0.082 12.8 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF996) MFS_1 PF07690.11 XP_011273501.1 - 1.1e-14 53.9 39.7 4.7e-14 51.8 24.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily His_Phos_2 PF00328.17 XP_011273502.1 - 4.5e-40 138.0 0.0 5.8e-40 137.6 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Aldo_ket_red PF00248.16 XP_011273503.1 - 1.7e-61 207.5 0.0 1.9e-61 207.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Exo_endo_phos PF03372.18 XP_011273504.1 - 1.6e-07 31.4 0.7 2.3e-07 31.0 0.5 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Jacalin PF01419.12 XP_011273504.1 - 0.00029 20.7 2.6 0.00056 19.8 1.8 1.5 1 0 0 1 1 1 1 Jacalin-like lectin domain Exo_endo_phos PF03372.18 XP_011273505.1 - 1.3e-08 35.0 0.2 2e-08 34.4 0.2 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Jacalin PF01419.12 XP_011273505.1 - 0.0015 18.3 0.2 0.0035 17.2 0.2 1.6 1 0 0 1 1 1 1 Jacalin-like lectin domain Pyr_redox_2 PF07992.9 XP_011273506.1 - 1.3e-15 57.7 0.0 2.3e-15 57.0 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 XP_011273506.1 - 0.00022 21.3 0.2 0.022 14.8 0.0 2.2 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 XP_011273506.1 - 0.0037 15.7 0.0 0.049 12.1 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 XP_011273506.1 - 0.0054 15.6 2.2 0.8 8.4 0.0 2.7 2 1 1 3 3 3 2 Glucose inhibited division protein A Zn_Tnp_IS1 PF03811.8 XP_011273506.1 - 0.0067 15.8 0.2 0.018 14.5 0.1 1.7 1 0 0 1 1 1 1 InsA N-terminal domain FAD_binding_2 PF00890.19 XP_011273506.1 - 0.011 14.5 0.0 0.59 8.9 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain DUF436 PF04260.7 XP_011273506.1 - 0.1 12.1 0.1 0.2 11.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF436) Zn_clus PF00172.13 XP_011273507.1 - 1.5e-07 31.1 11.7 3.7e-07 29.9 8.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TauD PF02668.11 XP_011273508.1 - 1.6e-48 165.6 0.0 2.2e-48 165.2 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family NIR_SIR PF01077.17 XP_011273509.1 - 8.9e-48 161.6 0.0 4.2e-42 143.1 0.0 2.5 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain Flavodoxin_1 PF00258.20 XP_011273509.1 - 6.4e-26 91.0 0.0 2.2e-25 89.3 0.0 2.0 2 0 0 2 2 2 1 Flavodoxin NIR_SIR_ferr PF03460.12 XP_011273509.1 - 8.1e-26 89.4 0.0 1.1e-12 47.4 0.0 2.5 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain FAD_binding_7 PF03441.9 XP_011273510.1 - 1.3e-88 296.7 0.1 2.3e-88 295.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 XP_011273510.1 - 3.4e-27 95.2 0.0 6e-27 94.4 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase LRR_8 PF13855.1 XP_011273511.1 - 2.5e-13 49.5 69.5 9.8e-08 31.6 7.1 8.2 5 2 3 8 8 8 6 Leucine rich repeat LRR_4 PF12799.2 XP_011273511.1 - 5.7e-13 48.1 90.2 3.6e-07 29.6 2.8 9.4 6 2 4 10 10 10 6 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 XP_011273511.1 - 0.018 15.0 70.1 0.47 10.6 0.4 13.7 11 2 3 14 14 14 0 Leucine Rich repeat AP4E_app_platf PF14807.1 XP_011273511.1 - 0.019 15.2 0.2 0.5 10.6 0.1 2.6 2 0 0 2 2 2 0 Adaptin AP4 complex epsilon appendage platform LRR_1 PF00560.28 XP_011273511.1 - 0.035 14.0 64.2 0.58 10.3 0.1 12.2 10 4 0 10 10 10 0 Leucine Rich Repeat LRR_7 PF13504.1 XP_011273511.1 - 0.26 11.6 39.9 1.7 9.1 0.1 12.0 12 1 1 13 13 13 0 Leucine rich repeat TORC_N PF12884.2 XP_011273512.1 - 0.031 14.7 1.1 0.031 14.7 0.8 2.3 2 0 0 2 2 2 0 Transducer of regulated CREB activity, N terminus Anthrax-tox_M PF09156.5 XP_011273513.1 - 0.012 14.7 0.1 0.016 14.3 0.1 1.3 1 0 0 1 1 1 0 Anthrax toxin lethal factor, middle domain adh_short PF00106.20 XP_011273514.1 - 1.6e-17 63.9 0.0 2.2e-17 63.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 XP_011273514.1 - 1.5e-14 54.3 0.3 1.9e-14 54.0 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 XP_011273514.1 - 1.9e-09 37.4 0.0 2.8e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 XP_011273514.1 - 0.0079 16.2 0.1 0.013 15.5 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding Fungal_trans PF04082.13 XP_011273515.1 - 4.7e-12 45.3 0.2 4.7e-12 45.3 0.2 3.1 3 1 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.13 XP_011273515.1 - 4.6e-11 42.4 10.5 1.1e-10 41.2 7.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1024 PF06260.7 XP_011273515.1 - 0.039 14.0 0.2 0.11 12.7 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1024) Fungal_trans PF04082.13 XP_011273516.1 - 6.7e-11 41.5 0.1 6.7e-11 41.5 0.1 2.3 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 XP_011273516.1 - 6.8e-10 38.6 11.2 6.8e-10 38.6 7.8 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RTA1 PF04479.8 XP_011273517.1 - 4e-24 85.3 26.1 9.8e-24 84.0 18.1 1.6 1 1 0 1 1 1 1 RTA1 like protein DUF4131 PF13567.1 XP_011273517.1 - 0.16 11.3 9.5 4.2 6.7 3.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Ninjurin PF04923.7 XP_011273517.1 - 1.2 8.8 11.3 0.79 9.4 0.7 3.6 2 1 2 4 4 4 0 Ninjurin EphA2_TM PF14575.1 XP_011273517.1 - 1.4 9.3 4.8 4.2 7.8 0.1 3.3 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Peptidase_M50B PF13398.1 XP_011273517.1 - 3.7 6.8 24.0 0.32 10.3 5.3 3.0 2 1 0 3 3 3 0 Peptidase M50B-like adh_short PF00106.20 XP_011273518.1 - 1.7e-20 73.5 0.0 2.2e-20 73.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 XP_011273518.1 - 3.7e-15 56.3 0.2 4.4e-15 56.0 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 XP_011273518.1 - 8.6e-12 45.0 0.0 1.1e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 XP_011273518.1 - 2.4e-05 24.4 0.0 3.5e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding MSC PF09402.5 XP_011273519.1 - 1.5e-88 296.6 9.3 1.5e-88 296.6 6.4 2.4 2 1 1 3 3 3 1 Man1-Src1p-C-terminal domain HeH PF12949.2 XP_011273519.1 - 3.8e-06 26.3 0.1 2.3e-05 23.8 0.0 2.4 2 0 0 2 2 2 1 HeH/LEM domain Pkinase PF00069.20 XP_011273520.1 - 2e-76 256.5 0.7 4.1e-76 255.5 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011273520.1 - 7.9e-39 133.2 0.0 1.4e-38 132.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.6 XP_011273520.1 - 1.8e-13 50.4 4.0 6.1e-13 48.7 2.8 2.0 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.1 XP_011273520.1 - 7.6e-08 31.6 0.0 1.9e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Kinase-like YukC PF10140.4 XP_011273520.1 - 0.00042 18.9 0.2 0.00077 18.1 0.1 1.4 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC APH PF01636.18 XP_011273520.1 - 0.011 15.4 0.2 0.41 10.3 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Zip PF02535.17 XP_011273520.1 - 0.71 8.8 2.5 1.1 8.2 1.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SIR2 PF02146.12 XP_011273521.1 - 4.2e-35 121.0 0.0 1.2e-33 116.3 0.0 2.4 1 1 0 1 1 1 1 Sir2 family DUF2039 PF10217.4 XP_011273521.1 - 0.016 15.1 0.3 0.016 15.1 0.2 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) zf-AD PF07776.10 XP_011273521.1 - 1.9 8.5 4.7 0.74 9.8 0.2 2.7 3 0 0 3 3 3 0 Zinc-finger associated domain (zf-AD) Rpr2 PF04032.11 XP_011273522.1 - 2.5e-13 49.6 3.9 4.6e-13 48.8 2.7 1.5 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Pex24p PF06398.6 XP_011273523.1 - 2.5e-77 260.0 13.9 3.7e-77 259.5 9.6 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin WD40 PF00400.27 XP_011273524.1 - 3e-07 30.0 4.7 0.0074 16.1 0.4 3.6 4 1 0 4 4 4 2 WD domain, G-beta repeat TRP PF06011.7 XP_011273525.1 - 5.6e-47 160.3 33.1 9.8e-38 129.8 16.1 2.2 2 0 0 2 2 2 2 Transient receptor potential (TRP) ion channel E1_DerP2_DerF2 PF02221.10 XP_011273525.1 - 0.088 13.0 0.0 0.3 11.3 0.0 1.8 1 1 0 1 1 1 0 ML domain SET PF00856.23 XP_011273526.1 - 7.5e-12 45.8 0.0 1.5e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 SET domain Antimicrobial_8 PF08103.6 XP_011273526.1 - 0.15 12.0 0.0 0.4 10.6 0.0 1.7 1 0 0 1 1 1 0 Uperin family TPR_11 PF13414.1 XP_011273527.1 - 3.2e-59 196.4 22.5 1.5e-18 66.1 0.7 6.4 5 1 2 7 7 7 6 TPR repeat TPR_1 PF00515.23 XP_011273527.1 - 2.6e-52 172.3 17.6 8e-08 31.5 0.2 9.5 8 1 1 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.12 XP_011273527.1 - 2.6e-41 136.1 21.1 4.5e-07 29.2 0.2 9.5 8 1 1 9 9 9 7 Tetratricopeptide repeat TPR_8 PF13181.1 XP_011273527.1 - 1.4e-25 87.0 21.7 0.00074 19.1 0.1 9.6 8 1 1 9 9 9 6 Tetratricopeptide repeat TPR_16 PF13432.1 XP_011273527.1 - 1.2e-23 83.1 12.7 1.6e-05 25.4 0.0 6.5 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 XP_011273527.1 - 4.3e-23 81.0 16.0 1.8e-09 37.4 0.0 6.3 3 3 4 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 XP_011273527.1 - 1.2e-21 75.2 7.6 0.018 15.6 0.1 9.9 5 3 5 10 10 9 3 Tetratricopeptide repeat TPR_19 PF14559.1 XP_011273527.1 - 2.1e-16 60.0 18.3 0.018 15.3 1.8 7.3 5 2 2 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.1 XP_011273527.1 - 6.6e-15 53.9 12.0 0.0058 16.7 0.0 8.4 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_7 PF13176.1 XP_011273527.1 - 1.6e-14 52.4 11.3 0.0014 18.2 0.0 7.6 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_9 PF13371.1 XP_011273527.1 - 5e-09 35.8 0.8 0.00028 20.6 0.0 4.5 5 2 1 6 6 5 2 Tetratricopeptide repeat Apc3 PF12895.2 XP_011273527.1 - 4.1e-07 30.0 13.4 0.009 16.1 0.7 4.8 3 2 3 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 XP_011273527.1 - 6.9e-07 29.3 21.8 1.7 9.2 0.1 8.6 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_10 PF13374.1 XP_011273527.1 - 0.00096 19.0 3.2 14 5.7 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 XP_011273527.1 - 0.00097 18.9 1.8 8.8 6.2 0.2 5.3 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat Auxin_repressed PF05564.7 XP_011273527.1 - 0.0036 17.9 3.1 0.36 11.4 0.9 3.0 2 1 0 2 2 2 1 Dormancy/auxin associated protein Inhibitor_I9 PF05922.11 XP_011273527.1 - 0.017 15.6 0.1 0.017 15.6 0.1 3.8 4 1 0 4 4 3 0 Peptidase inhibitor I9 ChAPs PF09295.5 XP_011273527.1 - 0.037 12.7 1.1 3.5 6.3 0.0 2.5 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_3 PF07720.7 XP_011273527.1 - 0.3 10.9 24.8 1.6 8.6 0.1 7.0 8 0 0 8 8 8 0 Tetratricopeptide repeat BTAD PF03704.12 XP_011273527.1 - 2.5 8.3 5.4 26 5.0 0.0 4.3 4 2 1 5 5 5 0 Bacterial transcriptional activator domain DUF498 PF04430.9 XP_011273528.1 - 6.8e-16 57.7 0.0 8.4e-16 57.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) L51_S25_CI-B8 PF05047.11 XP_011273529.1 - 2.5e-13 49.5 0.1 3.6e-13 49.0 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Img2 PF05046.9 XP_011273529.1 - 0.12 12.6 0.0 0.22 11.7 0.0 1.5 1 1 0 1 1 1 0 Mitochondrial large subunit ribosomal protein (Img2) NP1-WLL PF11733.3 XP_011273530.1 - 0.038 14.2 4.8 0.1 12.8 0.3 2.4 2 0 0 2 2 2 0 Non-capsid protein NP1 SRRM_C PF15230.1 XP_011273530.1 - 0.14 12.2 9.3 0.61 10.2 0.6 2.6 2 0 0 2 2 2 0 Serine/arginine repetitive matrix protein C-terminus CH PF00307.26 XP_011273531.1 - 0.0041 17.1 0.0 0.006 16.6 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain Peroxin-22 PF12827.2 XP_011273532.1 - 6.4e-23 80.6 1.3 6.4e-23 80.6 0.9 1.6 1 1 1 2 2 2 1 Peroxisomal biogenesis protein family Rad1 PF02144.11 XP_011273533.1 - 3.5e-52 176.8 14.6 1.4e-43 148.6 7.0 2.2 2 0 0 2 2 2 2 Repair protein Rad1/Rec1/Rad17 Ribosomal_L7Ae PF01248.21 XP_011273534.1 - 8.5e-22 76.4 0.1 1.1e-21 76.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family GDI PF00996.13 XP_011273535.1 - 7.1e-57 192.6 0.1 9.5e-57 192.2 0.0 1.1 1 0 0 1 1 1 1 GDP dissociation inhibitor Flavodoxin_1 PF00258.20 XP_011273538.1 - 2.1e-09 37.5 0.0 3.3e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin FMN_red PF03358.10 XP_011273538.1 - 2.8e-08 33.4 0.0 4.1e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 XP_011273538.1 - 0.0005 19.6 0.0 0.00066 19.2 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_5 PF12724.2 XP_011273538.1 - 0.09 12.7 0.0 0.56 10.1 0.0 1.9 1 1 0 2 2 2 0 Flavodoxin domain Bacteriocin_IIc PF10439.4 XP_011273538.1 - 1 9.5 6.4 1.1 9.4 1.4 2.3 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Flavodoxin_1 PF00258.20 XP_011273539.1 - 3.7e-09 36.7 0.1 9.7e-09 35.3 0.0 1.7 2 0 0 2 2 2 1 Flavodoxin FMN_red PF03358.10 XP_011273539.1 - 8.8e-08 31.7 0.0 1.4e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 XP_011273539.1 - 0.0045 16.5 0.0 0.011 15.3 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin-like fold MDFI PF15316.1 XP_011273539.1 - 0.91 9.4 8.3 1.3 9.0 5.8 1.2 1 0 0 1 1 1 0 MyoD family inhibitor Mucin PF01456.12 XP_011273539.1 - 1.2 8.8 18.3 1.9 8.2 12.7 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF2201_N PF13203.1 XP_011273539.1 - 1.4 8.0 8.0 1.9 7.5 5.6 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Ribosomal_L32p PF01783.18 XP_011273540.1 - 1.1e-08 35.1 5.0 1.9e-08 34.3 3.5 1.4 1 0 0 1 1 1 1 Ribosomal L32p protein family NRDD PF13597.1 XP_011273540.1 - 0.15 10.1 0.9 0.22 9.5 0.6 1.1 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase Septin PF00735.13 XP_011273541.1 - 5.3e-104 347.1 2.7 6.4e-104 346.9 1.9 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 XP_011273541.1 - 6.5e-09 35.7 0.4 1.7e-08 34.4 0.3 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 XP_011273541.1 - 2e-06 27.0 0.1 3.6e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 XP_011273541.1 - 1.5e-05 24.2 0.0 3e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 AIG1 family AAA_23 PF13476.1 XP_011273541.1 - 0.00043 20.6 1.7 0.00043 20.6 1.2 1.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 XP_011273541.1 - 0.0022 18.0 0.0 0.004 17.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 XP_011273541.1 - 0.0028 17.1 0.0 0.0048 16.4 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family GTP_EFTU PF00009.22 XP_011273541.1 - 0.0042 16.5 0.3 0.096 12.1 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain T2SE PF00437.15 XP_011273541.1 - 0.0053 15.6 0.1 0.01 14.7 0.1 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Dynamin_N PF00350.18 XP_011273541.1 - 0.0065 16.3 4.1 0.27 11.0 0.0 2.7 2 1 1 3 3 2 2 Dynamin family Miro PF08477.8 XP_011273541.1 - 0.021 15.2 0.1 0.06 13.8 0.1 2.0 1 1 0 1 1 1 0 Miro-like protein AAA_14 PF13173.1 XP_011273541.1 - 0.022 14.6 1.5 0.086 12.7 0.0 2.6 3 1 0 3 3 3 0 AAA domain Gtr1_RagA PF04670.7 XP_011273541.1 - 0.022 13.9 0.2 0.19 10.8 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_24 PF13479.1 XP_011273541.1 - 0.035 13.6 0.0 0.051 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 XP_011273541.1 - 0.038 13.5 0.0 0.1 12.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 XP_011273541.1 - 0.039 14.1 0.5 0.19 11.8 0.4 2.2 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 XP_011273541.1 - 0.053 12.9 0.1 0.097 12.0 0.1 1.4 1 0 0 1 1 1 0 AAA-like domain PRONE PF03759.8 XP_011273541.1 - 0.086 11.3 0.1 1.4 7.3 0.0 2.1 1 1 1 2 2 2 0 PRONE (Plant-specific Rop nucleotide exchanger) ABC_tran PF00005.22 XP_011273541.1 - 0.2 11.9 2.6 0.53 10.5 0.4 2.4 2 1 0 2 2 2 0 ABC transporter Glyco_transf_8 PF01501.15 XP_011273542.1 - 2e-36 125.6 0.2 2.9e-36 125.0 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 XP_011273542.1 - 0.0057 16.0 0.1 0.0083 15.5 0.0 1.4 1 0 0 1 1 1 1 Mannosyltransferase putative Phosphoesterase PF04185.9 XP_011273543.1 - 2.6e-36 125.6 9.1 1.2e-35 123.4 6.3 2.0 1 1 0 1 1 1 1 Phosphoesterase family Zip PF02535.17 XP_011273544.1 - 4 6.3 7.4 6 5.7 5.1 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Epimerase PF01370.16 XP_011273545.1 - 1.7e-45 155.2 0.0 2.1e-45 155.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 XP_011273545.1 - 1.4e-15 56.8 0.0 1.4e-14 53.6 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 XP_011273545.1 - 1.3e-13 50.5 0.0 3.3e-13 49.1 0.0 1.7 2 1 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 XP_011273545.1 - 1.4e-09 37.2 0.1 1.5e-08 33.9 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 XP_011273545.1 - 3.3e-07 29.2 0.1 4.5e-07 28.8 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Anticodon_1 PF08264.8 XP_011273545.1 - 0.063 13.0 0.2 0.17 11.6 0.2 1.6 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA adh_short PF00106.20 XP_011273545.1 - 0.064 13.1 0.1 0.25 11.2 0.0 1.8 2 0 0 2 2 2 0 short chain dehydrogenase KR PF08659.5 XP_011273545.1 - 0.18 11.4 0.0 0.27 10.8 0.0 1.2 1 0 0 1 1 1 0 KR domain Aldose_epim PF01263.15 XP_011273546.1 - 2.1e-65 220.8 0.3 2.9e-65 220.3 0.2 1.2 1 0 0 1 1 1 1 Aldose 1-epimerase Epimerase PF01370.16 XP_011273546.1 - 2.6e-48 164.5 0.0 4.3e-48 163.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 XP_011273546.1 - 9.7e-24 83.0 0.0 2e-23 82.0 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 XP_011273546.1 - 1.7e-17 63.0 0.2 3.8e-17 61.9 0.1 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 XP_011273546.1 - 2.7e-16 59.3 0.1 1.3e-14 53.8 0.0 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 XP_011273546.1 - 9.6e-13 47.6 0.0 2e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 XP_011273546.1 - 4.9e-10 38.7 0.1 9.6e-09 34.5 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 XP_011273546.1 - 1.1e-08 35.1 0.1 5.1e-08 33.0 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.1 XP_011273546.1 - 8.7e-08 32.3 0.0 1.5e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 XP_011273546.1 - 3.2e-06 26.9 0.0 6.4e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 XP_011273546.1 - 0.0081 15.4 0.3 0.015 14.5 0.2 1.4 1 0 0 1 1 1 1 NmrA-like family UDPG_MGDP_dh_N PF03721.9 XP_011273546.1 - 0.05 12.9 0.1 0.082 12.2 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.19 XP_011273546.1 - 0.17 10.7 0.4 0.26 10.1 0.3 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_8 PF08022.7 XP_011273547.1 - 2.4e-18 65.9 0.2 7.5e-18 64.3 0.0 1.8 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.7 XP_011273547.1 - 2.9e-11 43.5 0.0 4.2e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.19 XP_011273547.1 - 0.0022 18.0 0.0 0.0094 16.0 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain F-box PF00646.28 XP_011273548.1 - 6.5e-05 22.4 2.8 8.1e-05 22.1 0.7 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 XP_011273548.1 - 0.0042 16.7 0.3 0.0095 15.6 0.2 1.6 1 0 0 1 1 1 1 F-box-like MFS_1 PF07690.11 XP_011273549.1 - 5.2e-33 114.2 52.6 1.6e-21 76.4 24.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans_2 PF11951.3 XP_011273550.1 - 5.1e-37 127.3 0.2 5.1e-37 127.3 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 XP_011273550.1 - 9.9e-07 28.5 11.1 2e-06 27.6 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Bac_luciferase PF00296.15 XP_011273551.1 - 3.3e-54 184.0 0.0 4.5e-54 183.6 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase RNA_pol_Rpb1_5 PF04998.12 XP_011273553.1 - 4.1e-108 360.8 0.3 7e-108 360.0 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 XP_011273553.1 - 1.1e-105 353.6 0.5 2e-105 352.7 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 XP_011273553.1 - 1.2e-71 239.9 0.0 3.2e-71 238.6 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 XP_011273553.1 - 3.4e-65 219.2 1.0 8.3e-65 218.0 0.5 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_7 PF04990.7 XP_011273553.1 - 2.1e-49 166.7 5.4 6.1e-49 165.2 3.7 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_3 PF04983.13 XP_011273553.1 - 1.6e-47 161.1 0.0 4.2e-47 159.8 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 XP_011273553.1 - 8.9e-36 121.9 0.2 2.4e-35 120.5 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 XP_011273553.1 - 1.9e-14 52.4 284.5 0.012 15.6 6.9 15.5 5 1 12 21 21 21 17 RNA polymerase Rpb1 C-terminal repeat Pro_isomerase PF00160.16 XP_011273554.1 - 3.8e-44 150.6 0.3 7.1e-44 149.7 0.2 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 XP_011273554.1 - 6.2e-12 44.9 1.5 6.6e-06 25.6 0.2 2.3 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 XP_011273554.1 - 2.6e-11 42.6 0.4 1.2e-07 30.9 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 XP_011273554.1 - 4e-11 41.9 0.3 6e-07 28.9 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 XP_011273554.1 - 2.7e-07 29.8 4.2 6.5e-06 25.5 0.1 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 XP_011273554.1 - 3.3e-06 26.9 0.2 0.006 16.4 0.1 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 XP_011273554.1 - 0.0015 18.8 0.1 0.012 16.0 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.1 XP_011273554.1 - 0.015 14.3 0.0 0.032 13.2 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.1 XP_011273554.1 - 0.032 14.8 0.0 0.14 12.8 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.1 XP_011273554.1 - 0.07 12.9 0.0 0.17 11.7 0.0 1.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2404 PF10296.4 XP_011273555.1 - 0.058 13.5 0.2 0.8 9.8 0.0 2.3 1 1 1 2 2 2 0 Putative integral membrane protein conserved region (DUF2404) WD40 PF00400.27 XP_011273558.1 - 2.3e-20 71.6 6.6 3.8e-06 26.5 0.0 6.7 6 0 0 6 6 6 4 WD domain, G-beta repeat SRA1 PF07304.6 XP_011273558.1 - 5.6e-09 35.9 0.0 5.6e-09 35.9 0.0 2.4 2 0 0 2 2 2 1 Steroid receptor RNA activator (SRA1) Prp18 PF02840.10 XP_011273558.1 - 0.15 11.8 0.3 1.8 8.3 0.1 2.5 1 1 1 2 2 2 0 Prp18 domain AMP-binding PF00501.23 XP_011273559.1 - 4.5e-61 206.4 0.0 1.2e-60 205.1 0.0 1.6 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.23 XP_011273560.1 - 1.9e-61 207.7 0.0 3.1e-61 207.0 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.23 XP_011273561.1 - 2.1e-67 227.3 0.0 2.8e-67 226.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_8 PF13450.1 XP_011273562.1 - 3e-10 39.9 0.0 6.6e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 XP_011273562.1 - 2.3e-06 27.9 0.1 0.0014 19.0 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 XP_011273562.1 - 6.3e-06 25.5 0.0 6e-05 22.3 0.0 2.3 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 XP_011273562.1 - 1.6e-05 23.9 0.0 3.3e-05 22.9 0.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 XP_011273562.1 - 0.001 18.2 0.0 0.0024 16.9 0.0 1.5 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 XP_011273562.1 - 0.0023 17.7 0.0 0.24 11.1 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Mqo PF06039.10 XP_011273562.1 - 0.0067 14.6 0.0 0.1 10.7 0.0 2.4 3 0 0 3 3 3 1 Malate:quinone oxidoreductase (Mqo) Pyr_redox_3 PF13738.1 XP_011273562.1 - 0.01 15.9 0.0 0.021 14.8 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 XP_011273562.1 - 0.012 13.8 0.0 0.02 13.1 0.0 1.3 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like GatB_Yqey PF02637.13 XP_011273562.1 - 0.019 14.6 0.4 0.048 13.3 0.3 1.7 1 0 0 1 1 1 0 GatB domain Pyr_redox_2 PF07992.9 XP_011273562.1 - 0.051 13.4 0.0 0.22 11.4 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF4277 PF14104.1 XP_011273562.1 - 0.068 13.3 0.2 2.7 8.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4277) Rad60-SLD PF11976.3 XP_011273563.1 - 0.07 12.8 0.3 0.69 9.6 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like SRP14 PF02290.10 XP_011273563.1 - 0.74 9.7 4.5 0.29 11.0 0.3 2.5 2 1 1 3 3 3 0 Signal recognition particle 14kD protein Rad60-SLD PF11976.3 XP_011273564.1 - 4e-05 23.2 1.6 0.051 13.2 0.0 2.8 3 0 0 3 3 3 2 Ubiquitin-2 like Rad60 SUMO-like RRM_1 PF00076.17 XP_011273565.1 - 3.4e-13 49.0 0.1 4.8e-13 48.5 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 XP_011273565.1 - 2.9e-11 43.0 0.0 4.6e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 XP_011273565.1 - 4.3e-08 33.0 0.0 6.2e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 XP_011273565.1 - 0.0016 18.1 0.0 0.0029 17.3 0.0 1.4 1 1 0 1 1 1 1 Limkain b1 Pcc1 PF09341.5 XP_011273565.1 - 0.022 14.7 0.0 0.055 13.5 0.0 1.7 1 0 0 1 1 1 0 Transcription factor Pcc1 Calcipressin PF04847.7 XP_011273565.1 - 0.079 12.5 0.1 0.22 11.0 0.0 1.7 1 1 1 2 2 2 0 Calcipressin Peptidase_M41 PF01434.13 XP_011273566.1 - 1.2e-70 237.2 0.6 2.1e-70 236.5 0.4 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 XP_011273566.1 - 3.2e-41 140.6 0.3 4e-40 137.0 0.0 2.5 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 XP_011273566.1 - 1e-05 25.6 0.2 0.0059 16.7 0.1 3.0 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.1 XP_011273566.1 - 3.9e-05 23.7 0.5 0.00024 21.1 0.1 2.5 2 1 0 2 2 1 1 AAA ATPase domain TIP49 PF06068.8 XP_011273566.1 - 4.9e-05 22.2 0.0 9.6e-05 21.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_17 PF13207.1 XP_011273566.1 - 8.4e-05 23.3 0.1 0.00031 21.5 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_5 PF07728.9 XP_011273566.1 - 0.00019 21.1 0.0 0.00071 19.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 XP_011273566.1 - 0.00051 19.5 1.0 0.081 12.3 0.5 2.5 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 XP_011273566.1 - 0.0023 17.6 2.2 0.0061 16.2 1.5 1.7 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 XP_011273566.1 - 0.0029 16.7 0.0 0.0072 15.4 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 XP_011273566.1 - 0.0042 16.5 0.0 0.0084 15.5 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein Cytochrom_C550 PF14495.1 XP_011273566.1 - 0.014 14.8 0.0 0.029 13.8 0.0 1.4 1 0 0 1 1 1 0 Cytochrome c-550 domain AAA_14 PF13173.1 XP_011273566.1 - 0.018 14.9 0.0 0.054 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 XP_011273566.1 - 0.024 13.7 0.1 0.44 9.6 0.1 2.5 2 0 0 2 2 2 0 KaiC Zeta_toxin PF06414.7 XP_011273566.1 - 0.027 13.5 0.1 0.058 12.4 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.1 XP_011273566.1 - 0.038 13.8 0.0 0.1 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 XP_011273566.1 - 0.039 13.1 0.8 0.088 11.9 0.1 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 XP_011273566.1 - 0.041 14.1 1.7 0.095 13.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain SpoU_sub_bind PF08032.7 XP_011273566.1 - 0.096 12.8 0.4 14 5.9 0.7 2.7 2 0 0 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding AAA_28 PF13521.1 XP_011273566.1 - 0.17 11.8 0.0 0.17 11.8 0.0 2.0 3 0 0 3 3 1 0 AAA domain PhoH PF02562.11 XP_011273566.1 - 0.23 10.6 1.6 0.36 10.0 0.3 1.8 2 0 0 2 2 2 0 PhoH-like protein Cnd2 PF05786.9 XP_011273567.1 - 2.9e-145 485.6 42.4 8.1e-145 484.1 29.4 1.5 1 1 0 1 1 1 1 Condensin complex subunit 2 Cyclin_N PF00134.18 XP_011273568.1 - 2.6e-14 52.8 0.5 2.6e-14 52.8 0.3 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Seryl_tRNA_N PF02403.17 XP_011273568.1 - 0.19 11.7 8.5 2.7 8.0 2.7 2.6 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain ATP-synt_ab PF00006.20 XP_011273569.1 - 1.8e-68 230.2 0.0 2.7e-68 229.7 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 XP_011273569.1 - 4.6e-27 94.7 1.1 1.2e-26 93.3 0.7 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 XP_011273569.1 - 5.3e-18 64.9 1.5 1.3e-17 63.7 1.1 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 XP_011273569.1 - 0.00086 19.1 0.7 0.0023 17.8 0.5 1.7 1 0 0 1 1 1 1 HAS barrel domain Tex_N PF09371.5 XP_011273569.1 - 0.011 15.0 0.2 0.032 13.5 0.0 1.8 2 0 0 2 2 2 0 Tex-like protein N-terminal domain AAA_25 PF13481.1 XP_011273569.1 - 0.097 12.0 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain TMEM206 PF15122.1 XP_011273570.1 - 0.028 13.3 0.2 0.56 9.0 0.0 2.3 2 0 0 2 2 2 0 TMEM206 protein family DUF3216 PF11505.3 XP_011273571.1 - 0.0029 17.3 0.1 0.0067 16.1 0.0 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF3216) Alpha-mann_mid PF09261.6 XP_011273571.1 - 0.086 13.0 0.0 0.13 12.4 0.0 1.5 1 1 0 1 1 1 0 Alpha mannosidase, middle domain Glyco_hydro_65m PF03632.10 XP_011273572.1 - 2.8e-91 305.9 1.3 2.2e-90 303.0 0.9 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.10 XP_011273572.1 - 4.1e-28 98.3 0.7 6.8e-28 97.6 0.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain F5_F8_type_C PF00754.20 XP_011273572.1 - 0.035 13.9 0.0 0.087 12.6 0.0 1.7 1 0 0 1 1 1 0 F5/8 type C domain Sigma_1s PF02454.11 XP_011273572.1 - 0.07 12.9 0.4 4.1 7.2 0.0 2.5 2 0 0 2 2 2 0 Sigma 1s protein Glyco_hydro_16 PF00722.16 XP_011273573.1 - 1.9e-40 138.1 5.4 1.9e-40 138.1 3.8 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 DUF3827 PF12877.2 XP_011273573.1 - 6.8 4.6 11.2 9.1 4.2 7.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Coatomer_WDAD PF04053.9 XP_011273574.1 - 3.2e-138 461.2 8.0 5.6e-138 460.4 5.6 1.4 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 XP_011273574.1 - 3.5e-71 239.9 0.0 6.9e-71 238.9 0.0 1.5 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus Tubulin PF00091.20 XP_011273574.1 - 3.8e-67 226.2 0.6 1e-66 224.8 0.4 1.7 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain WD40 PF00400.27 XP_011273574.1 - 1.6e-53 176.7 16.3 3.2e-10 39.4 0.0 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat Tubulin_C PF03953.12 XP_011273574.1 - 2.6e-21 75.9 0.1 8.3e-21 74.3 0.0 2.0 2 0 0 2 2 2 1 Tubulin C-terminal domain Nup160 PF11715.3 XP_011273574.1 - 2.2e-05 22.8 6.4 0.3 9.1 0.0 3.7 2 1 1 3 3 3 3 Nucleoporin Nup120/160 Misat_Tub_SegII PF10644.4 XP_011273574.1 - 0.0028 17.6 0.0 0.0083 16.1 0.0 1.8 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain APP_N PF02177.11 XP_011273574.1 - 0.013 15.4 0.2 0.11 12.4 0.0 2.6 2 0 0 2 2 2 0 Amyloid A4 N-terminal heparin-binding DUF2013 PF09431.5 XP_011273575.1 - 2.6e-46 156.8 10.0 7.8e-46 155.3 6.9 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) MIT PF04212.13 XP_011273576.1 - 0.00017 21.4 1.7 0.00054 19.7 1.2 1.8 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Myb_DNA-bind_5 PF13873.1 XP_011273576.1 - 0.61 10.0 10.2 0.31 10.9 4.3 2.4 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain ADIP PF11559.3 XP_011273576.1 - 5.1 6.9 27.4 2.4 8.0 9.8 2.9 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding PCI PF01399.22 XP_011273577.1 - 9.3e-20 70.9 1.1 9.3e-20 70.9 0.7 2.2 2 0 0 2 2 2 1 PCI domain OspE PF02471.12 XP_011273577.1 - 0.0092 15.8 0.6 0.032 14.0 0.0 2.2 2 0 0 2 2 2 1 Borrelia outer surface protein E Retrotrans_gag PF03732.12 XP_011273577.1 - 0.39 10.8 2.6 3.9 7.6 0.2 2.7 2 1 0 2 2 2 0 Retrotransposon gag protein Nop14 PF04147.7 XP_011273578.1 - 4.3e-217 722.9 83.2 5e-125 418.4 15.4 2.0 1 1 1 2 2 2 2 Nop14-like family APG9 PF04109.11 XP_011273579.1 - 1.8e-170 566.7 4.0 2.5e-170 566.3 2.8 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 RNA_pol_Rpc4 PF05132.9 XP_011273580.1 - 2.7e-31 108.2 0.2 2.7e-31 108.2 0.2 2.2 3 0 0 3 3 3 1 RNA polymerase III RPC4 Stm1_N PF09598.5 XP_011273580.1 - 0.04 14.6 5.5 0.04 14.6 3.8 3.4 3 0 0 3 3 3 0 Stm1 RNase_HII PF01351.13 XP_011273580.1 - 0.046 13.3 0.3 0.077 12.6 0.2 1.3 1 0 0 1 1 1 0 Ribonuclease HII FoP_duplication PF13865.1 XP_011273580.1 - 0.54 10.7 4.8 1.6 9.2 3.3 1.8 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Sas10 PF09368.5 XP_011273581.1 - 2.5e-32 110.8 9.0 2.5e-32 110.8 6.2 2.4 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 XP_011273581.1 - 4.1e-11 42.9 1.3 1.1e-10 41.5 0.0 2.4 2 0 0 2 2 2 1 Sas10/Utp3/C1D family DUF4488 PF14869.1 XP_011273582.1 - 0.0088 15.6 0.5 0.011 15.3 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4488) MutS_V PF00488.16 XP_011273583.1 - 3.3e-54 183.7 0.1 5.3e-54 183.1 0.1 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 XP_011273583.1 - 3.2e-28 98.9 0.0 7.2e-28 97.7 0.0 1.6 2 0 0 2 2 2 1 MutS domain III SMC_N PF02463.14 XP_011273583.1 - 0.016 14.4 1.4 2.8 7.1 0.1 3.2 4 0 0 4 4 4 0 RecF/RecN/SMC N terminal domain AAA_14 PF13173.1 XP_011273583.1 - 0.021 14.7 0.1 0.42 10.5 0.0 3.0 2 0 0 2 2 2 0 AAA domain CSTF2_hinge PF14327.1 XP_011273583.1 - 0.082 13.0 0.8 0.51 10.4 0.0 2.4 2 0 0 2 2 2 0 Hinge domain of cleavage stimulation factor subunit 2 D123 PF07065.9 XP_011273584.1 - 1.8e-107 358.9 4.1 1.8e-107 358.9 2.9 1.5 2 0 0 2 2 2 1 D123 Sigma70_ner PF04546.8 XP_011273584.1 - 0.026 14.1 0.6 0.026 14.1 0.4 2.8 4 0 0 4 4 4 0 Sigma-70, non-essential region Cpn60_TCP1 PF00118.19 XP_011273585.1 - 8e-135 450.1 12.5 9e-135 450.0 8.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CDP-OH_P_transf PF01066.16 XP_011273586.1 - 1.4e-19 70.2 4.7 2.9e-19 69.2 3.2 1.5 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase MFS_1_like PF12832.2 XP_011273586.1 - 0.016 14.9 1.9 0.87 9.4 0.5 2.7 1 1 1 2 2 2 0 MFS_1 like family DUF1436 PF07262.6 XP_011273586.1 - 0.045 13.2 0.2 0.075 12.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1436) DUF1177 PF06675.6 XP_011273586.1 - 0.068 11.7 0.0 0.099 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1177) Rrn6 PF10214.4 XP_011273588.1 - 3.3e-75 253.6 31.8 3e-74 250.5 22.0 2.2 1 1 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor AAT PF03417.11 XP_011273589.1 - 1.1e-29 103.4 0.0 1.7e-29 102.9 0.0 1.2 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase F-box PF00646.28 XP_011273590.1 - 0.011 15.3 0.0 0.038 13.6 0.0 1.9 1 0 0 1 1 1 0 F-box domain YccV-like PF08755.6 XP_011273590.1 - 0.02 14.8 1.4 0.031 14.1 0.1 2.0 2 0 0 2 2 2 0 Hemimethylated DNA-binding protein YccV like F-box-like PF12937.2 XP_011273590.1 - 0.072 12.8 0.4 0.22 11.2 0.1 2.1 2 0 0 2 2 2 0 F-box-like F-box PF00646.28 XP_011273591.1 - 0.0064 16.1 0.0 0.016 14.8 0.0 1.7 1 0 0 1 1 1 1 F-box domain MarR_2 PF12802.2 XP_011273591.1 - 0.22 11.1 0.9 44 3.8 0.0 3.2 3 0 0 3 3 3 0 MarR family Histone PF00125.19 XP_011273592.1 - 1e-25 89.6 0.0 1.3e-25 89.2 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 XP_011273592.1 - 8e-06 25.8 0.0 1.1e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 XP_011273593.1 - 3e-22 78.4 0.2 4.2e-22 78.0 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 XP_011273593.1 - 1.3e-07 31.5 0.1 2.6e-07 30.5 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 XP_011273593.1 - 0.0041 17.3 0.0 0.007 16.6 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Fe_hyd_lg_C PF02906.9 XP_011273594.1 - 7.3e-71 238.7 0.0 1e-70 238.2 0.0 1.2 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Peptidase_C1_2 PF03051.10 XP_011273595.1 - 1.1e-163 544.7 5.9 1.3e-163 544.5 4.1 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 XP_011273595.1 - 1.2e-07 31.8 1.1 0.003 17.4 0.3 3.3 2 2 0 2 2 2 2 Papain family cysteine protease Peptidase_S8 PF00082.17 XP_011273596.1 - 1.7e-54 184.8 2.9 3.6e-54 183.8 2.0 1.5 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 XP_011273596.1 - 1.1e-21 76.3 0.5 3.7e-21 74.7 0.4 2.0 1 0 0 1 1 1 1 Proprotein convertase P-domain ABC2_membrane_3 PF12698.2 XP_011273596.1 - 3.5 6.5 11.5 0.088 11.8 2.8 2.0 1 1 1 2 2 2 0 ABC-2 family transporter protein ETRAMP PF09716.5 XP_011273596.1 - 4.4 7.3 6.1 0.94 9.4 0.6 2.6 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Ytp1 PF10355.4 XP_011273597.1 - 1e-73 247.9 11.8 1.8e-73 247.0 8.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF3704 PF12488.3 XP_011273597.1 - 0.16 11.6 6.2 0.11 12.1 0.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3704) Ninjurin PF04923.7 XP_011273597.1 - 0.16 11.6 1.4 0.72 9.6 0.1 2.7 3 0 0 3 3 3 0 Ninjurin zf-DHHC PF01529.15 XP_011273597.1 - 0.5 9.7 3.5 4.4 6.6 2.5 2.6 1 1 0 1 1 1 0 DHHC palmitoyltransferase ELFV_dehydrog PF00208.16 XP_011273598.1 - 5.2e-80 268.5 2.7 6.4e-80 268.2 1.8 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 XP_011273598.1 - 1.6e-44 150.6 0.0 3e-44 149.7 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.1 XP_011273598.1 - 0.13 12.5 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Med16 PF11635.3 XP_011273599.1 - 1.5e-120 403.4 4.4 2.1e-120 402.9 3.0 1.1 1 0 0 1 1 1 1 Mediator complex subunit 16 Cytochrome_cB PF11783.3 XP_011273599.1 - 0.17 11.4 0.0 0.32 10.5 0.0 1.3 1 0 0 1 1 1 0 Cytochrome c bacterial TauD PF02668.11 XP_011273600.1 - 3.9e-55 187.3 0.1 5.5e-55 186.8 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Adeno_PVIII PF01310.13 XP_011273600.1 - 0.036 13.8 0.0 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 Adenovirus hexon associated protein, protein VIII Aldo_ket_red PF00248.16 XP_011273601.1 - 4.1e-63 212.8 0.2 4.7e-63 212.6 0.2 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_97 PF10566.4 XP_011273601.1 - 0.078 12.0 0.3 0.87 8.6 0.1 2.4 1 1 1 2 2 2 0 Glycoside hydrolase 97 Globin PF00042.17 XP_011273602.1 - 2.2e-07 31.1 0.0 5.8e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 Globin Trp_syntA PF00290.15 XP_011273604.1 - 7.7e-92 306.4 0.1 1.1e-91 305.9 0.1 1.2 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 XP_011273604.1 - 6e-45 153.7 2.6 1e-44 153.0 0.6 2.0 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme HMGL-like PF00682.14 XP_011273604.1 - 0.042 13.4 0.0 1.4 8.5 0.0 2.5 2 0 0 2 2 2 0 HMGL-like UBA PF00627.26 XP_011273605.1 - 0.018 14.8 0.0 0.033 14.0 0.0 1.5 1 0 0 1 1 1 0 UBA/TS-N domain Mnd1 PF03962.10 XP_011273606.1 - 6.4e-41 140.0 7.3 7.4e-41 139.8 5.1 1.0 1 0 0 1 1 1 1 Mnd1 family UBA_3 PF09288.5 XP_011273606.1 - 0.002 17.6 0.1 0.006 16.1 0.1 1.8 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain PspB PF06667.7 XP_011273606.1 - 0.0027 17.5 0.1 0.0065 16.3 0.0 1.6 1 0 0 1 1 1 1 Phage shock protein B LUC7 PF03194.10 XP_011273606.1 - 0.12 11.8 6.3 0.17 11.3 4.4 1.1 1 0 0 1 1 1 0 LUC7 N_terminus DUF1664 PF07889.7 XP_011273606.1 - 0.23 11.2 5.5 0.13 12.0 0.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) KxDL PF10241.4 XP_011273606.1 - 0.43 10.5 5.5 15 5.5 3.5 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein DUF1359 PF07097.6 XP_011273606.1 - 1.7 8.6 7.6 6.2 6.9 4.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1359) Fib_alpha PF08702.5 XP_011273606.1 - 2.5 8.2 6.7 5.8 7.0 4.1 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Osmo_CC PF08946.5 XP_011273606.1 - 5.3 7.1 10.5 0.8 9.7 1.1 3.2 3 0 0 3 3 3 0 Osmosensory transporter coiled coil DUF3543 PF12063.3 XP_011273607.1 - 6.5e-78 261.2 5.5 1.2e-77 260.2 3.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.20 XP_011273607.1 - 3.7e-60 203.2 0.0 7.5e-60 202.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011273607.1 - 1.2e-41 142.4 0.0 2e-41 141.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Spore_II_R PF09551.5 XP_011273607.1 - 3.4 7.7 8.0 0.59 10.1 0.1 3.0 3 0 0 3 3 3 0 Stage II sporulation protein R (spore_II_R) Clathrin_lg_ch PF01086.12 XP_011273608.1 - 3.8e-42 144.7 37.7 4.3e-42 144.5 26.2 1.0 1 0 0 1 1 1 1 Clathrin light chain rve_3 PF13683.1 XP_011273608.1 - 0.025 14.1 2.4 0.77 9.3 0.2 2.8 3 0 0 3 3 3 0 Integrase core domain PLRV_ORF5 PF01690.12 XP_011273608.1 - 4.7 6.2 17.8 5.1 6.1 12.4 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein CTD_bind PF04818.8 XP_011273609.1 - 4.4e-22 78.0 1.0 4.4e-22 78.0 0.7 2.3 3 0 0 3 3 3 1 RNA polymerase II-binding domain. ZYG-11_interact PF05884.7 XP_011273609.1 - 0.23 10.5 0.3 0.42 9.6 0.1 1.5 1 1 0 1 1 1 0 Interactor of ZYG-11 MFS_1 PF07690.11 XP_011273610.1 - 1e-11 44.1 37.2 6.2e-09 35.0 25.3 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1049 PF06305.6 XP_011273610.1 - 0.58 9.6 0.0 0.58 9.6 0.0 4.3 5 0 0 5 5 5 0 Protein of unknown function (DUF1049) zf-C2H2 PF00096.21 XP_011273611.1 - 3.7e-11 42.6 16.5 5.3e-06 26.4 0.5 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 XP_011273611.1 - 4.4e-11 42.3 12.0 2.1e-05 24.5 0.2 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 XP_011273611.1 - 1.6e-09 37.5 14.8 4.4e-08 33.0 3.0 3.7 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 XP_011273611.1 - 3.8e-09 36.4 8.3 0.00052 20.0 1.7 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 XP_011273611.1 - 6.6e-06 25.8 8.1 0.0021 17.8 0.1 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 XP_011273611.1 - 0.00013 22.0 5.5 0.11 12.6 0.4 2.9 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-Di19 PF05605.7 XP_011273611.1 - 0.00043 20.3 2.6 0.00091 19.3 1.8 1.6 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.10 XP_011273611.1 - 0.018 14.7 8.1 0.098 12.4 1.4 3.2 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_2 PF12756.2 XP_011273611.1 - 0.11 12.6 9.1 0.56 10.3 0.6 3.4 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.1 XP_011273611.1 - 0.37 10.4 6.7 3.7 7.3 0.1 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type ABC2_membrane PF01061.19 XP_011273612.1 - 5.6e-21 74.6 17.4 5.6e-21 74.6 12.1 1.3 2 0 0 2 2 2 1 ABC-2 type transporter MFS_1 PF07690.11 XP_011273613.1 - 2.7e-40 138.1 35.0 6.2e-40 136.9 24.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 XP_011273613.1 - 1.5e-11 43.5 14.7 1.5e-11 43.5 10.2 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.8 XP_011273613.1 - 0.00037 18.7 2.2 0.00037 18.7 1.5 1.4 2 0 0 2 2 2 1 Transmembrane secretion effector OATP PF03137.15 XP_011273613.1 - 0.031 12.3 12.8 0.2 9.6 2.6 2.4 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family RseC_MucC PF04246.7 XP_011273613.1 - 0.07 12.7 4.7 0.058 12.9 1.2 2.6 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Carbpep_Y_N PF05388.6 XP_011273613.1 - 0.12 12.4 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Carboxypeptidase Y pro-peptide MFS_1 PF07690.11 XP_011273614.1 - 4.7e-42 143.9 27.2 4.7e-42 143.9 18.9 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_3 PF05977.8 XP_011273614.1 - 6.8e-05 21.1 2.7 6.8e-05 21.1 1.8 1.7 2 0 0 2 2 2 1 Transmembrane secretion effector OATP PF03137.15 XP_011273614.1 - 0.049 11.6 9.0 0.051 11.6 1.5 2.5 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Nramp PF01566.13 XP_011273615.1 - 6e-90 301.6 13.3 6e-90 301.6 9.2 1.5 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein Phe_ZIP PF08916.6 XP_011273616.1 - 0.0055 17.0 2.6 24 5.3 0.1 3.9 1 1 3 4 4 4 2 Phenylalanine zipper MF_alpha_N PF05436.6 XP_011273616.1 - 0.28 10.8 1.6 2.1 8.0 1.1 2.1 1 1 0 1 1 1 0 Mating factor alpha precursor N-terminus BCA_ABC_TP_C PF12399.3 XP_011273618.1 - 2.8e-05 23.6 0.3 5.4 6.8 0.0 3.3 3 0 0 3 3 3 3 Branched-chain amino acid ATP-binding cassette transporter AMP-binding PF00501.23 XP_011273619.1 - 4.4e-85 285.5 0.0 5.2e-85 285.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme RESP18 PF14948.1 XP_011273619.1 - 0.14 12.2 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 RESP18 domain NTP_transferase PF00483.18 XP_011273620.1 - 7.8e-49 166.2 0.0 1.2e-48 165.6 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 XP_011273620.1 - 2.9e-16 58.1 7.2 5e-09 35.2 0.6 3.7 1 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 XP_011273620.1 - 1.3e-10 41.6 0.0 1.8e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 XP_011273620.1 - 0.00015 21.2 2.0 0.0056 16.2 0.1 3.1 4 0 0 4 4 4 1 Hexapeptide repeat of succinyl-transferase CTP_transf_3 PF02348.14 XP_011273620.1 - 0.072 12.7 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Cytidylyltransferase KilA-N PF04383.8 XP_011273621.1 - 0.0062 16.1 0.0 0.39 10.3 0.0 3.5 3 0 0 3 3 3 1 KilA-N domain Ank_2 PF12796.2 XP_011273622.1 - 3.3e-19 69.0 1.0 5.4e-08 33.0 0.0 3.5 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 XP_011273622.1 - 1.3e-17 63.8 0.3 1.3e-08 35.0 0.0 3.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 XP_011273622.1 - 1.5e-17 62.4 1.4 1.7e-07 30.6 0.1 4.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 XP_011273622.1 - 2e-15 56.4 2.7 1e-06 28.8 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 XP_011273622.1 - 6.6e-12 44.4 5.7 4.8e-05 23.2 0.0 5.3 6 0 0 6 6 6 3 Ankyrin repeat KilA-N PF04383.8 XP_011273622.1 - 3.6e-07 29.7 1.2 2.6e-06 26.9 0.0 3.0 2 2 0 2 2 2 1 KilA-N domain TNV_CP PF03898.8 XP_011273622.1 - 0.59 9.1 4.0 0.46 9.5 1.2 1.9 2 0 0 2 2 2 0 Satellite tobacco necrosis virus coat protein PEX11 PF05648.9 XP_011273626.1 - 1.4e-14 53.9 2.8 6.3e-11 41.9 0.6 2.6 2 1 0 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) Asp_protease_2 PF13650.1 XP_011273627.1 - 5.9e-09 36.3 0.2 2.5e-08 34.3 0.0 2.1 2 1 1 3 3 3 1 Aspartyl protease gag-asp_proteas PF13975.1 XP_011273627.1 - 1.1e-07 31.5 0.0 2e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Peptidase_A2B PF12384.3 XP_011273627.1 - 2.2e-06 27.1 0.1 1.1e-05 24.8 0.0 2.1 2 0 0 2 2 2 1 Ty3 transposon peptidase Asp_protease PF09668.5 XP_011273627.1 - 5.6e-06 25.9 0.0 1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease DUF1758 PF05585.7 XP_011273627.1 - 0.01 15.4 0.1 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF1758) RVP PF00077.15 XP_011273627.1 - 0.046 13.6 0.2 0.9 9.4 0.0 3.0 3 0 0 3 3 3 0 Retroviral aspartyl protease RVP_2 PF08284.6 XP_011273627.1 - 0.054 13.4 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease PNGaseA PF12222.3 XP_011273627.1 - 0.9 8.3 4.7 1.5 7.6 3.2 1.2 1 0 0 1 1 1 0 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A Retrotrans_gag PF03732.12 XP_011273628.1 - 2e-15 56.6 3.4 3.7e-15 55.7 0.0 2.8 4 0 0 4 4 4 1 Retrotransposon gag protein zf-CCHC PF00098.18 XP_011273628.1 - 8.7e-07 28.5 0.6 1.3e-06 28.0 0.4 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 XP_011273628.1 - 0.00046 19.6 0.1 0.001 18.4 0.1 1.6 1 0 0 1 1 1 1 Zinc knuckle Bromo_TP PF07524.8 XP_011273628.1 - 0.0094 15.6 0.1 2 8.2 0.0 2.4 2 0 0 2 2 2 2 Bromodomain associated SCAN PF02023.12 XP_011273628.1 - 0.011 15.1 1.6 0.036 13.5 0.1 2.4 3 0 0 3 3 3 0 SCAN domain Latarcin PF10279.4 XP_011273628.1 - 0.014 15.6 0.0 0.18 12.0 0.0 2.7 2 1 0 2 2 2 0 Latarcin precursor zf-CCHC_4 PF14392.1 XP_011273628.1 - 0.025 14.2 0.5 0.064 12.9 0.4 1.7 1 0 0 1 1 1 0 Zinc knuckle RVT_2 PF07727.9 XP_011273629.1 - 5e-34 117.3 0.1 9.8e-34 116.4 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PP2C PF00481.16 XP_011273630.1 - 1.5e-42 145.7 0.0 3.3e-42 144.6 0.0 1.5 2 0 0 2 2 2 1 Protein phosphatase 2C Ras PF00071.17 XP_011273631.1 - 4.6e-60 201.6 0.1 5.4e-60 201.4 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 XP_011273631.1 - 4.2e-20 72.4 0.0 6.7e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 XP_011273631.1 - 7.5e-15 54.6 0.0 9.4e-15 54.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 XP_011273631.1 - 1.2e-07 31.1 0.0 1.5e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 XP_011273631.1 - 8.5e-06 25.3 0.0 2.5e-05 23.7 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 XP_011273631.1 - 4.3e-05 23.4 0.0 7.6e-05 22.6 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 XP_011273631.1 - 0.0091 16.0 0.0 0.013 15.4 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain N2227 PF07942.7 XP_011273632.1 - 4.3e-84 281.6 0.6 5.6e-84 281.2 0.4 1.2 1 0 0 1 1 1 1 N2227-like protein DUF1108 PF06531.6 XP_011273632.1 - 0.0099 16.0 0.6 0.035 14.2 0.3 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1108) Methyltransf_12 PF08242.7 XP_011273632.1 - 0.015 15.7 0.0 0.042 14.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 XP_011273632.1 - 0.049 13.2 0.0 0.21 11.1 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.1 XP_011273632.1 - 0.066 12.9 0.0 0.087 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 XP_011273632.1 - 0.071 13.5 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PKD_channel PF08016.7 XP_011273633.1 - 0.0013 17.1 13.7 0.066 11.6 9.5 2.2 1 1 0 1 1 1 1 Polycystin cation channel DNase-RNase PF02577.9 XP_011273633.1 - 0.081 12.1 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Bifunctional nuclease Malate_synthase PF01274.17 XP_011273634.1 - 2.2e-217 722.2 0.0 2.7e-217 721.9 0.0 1.0 1 0 0 1 1 1 1 Malate synthase HpcH_HpaI PF03328.9 XP_011273634.1 - 0.15 10.9 0.0 0.27 10.0 0.0 1.4 1 0 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family NMT1 PF09084.6 XP_011273635.1 - 1.9e-12 47.2 0.0 1.7e-11 44.1 0.0 2.1 1 1 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.1 XP_011273635.1 - 2.7e-06 26.9 0.0 4.1e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 NMT1-like family DUF3834 PF12916.2 XP_011273635.1 - 0.0016 17.4 0.4 0.004 16.1 0.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3834) DUF1223 PF06764.6 XP_011273635.1 - 0.028 14.2 0.0 0.089 12.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1223) DCP2 PF05026.8 XP_011273636.1 - 8e-26 89.7 0.1 2.3e-25 88.2 0.1 1.9 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 XP_011273636.1 - 4.4e-13 49.0 0.0 1.2e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 NUDIX domain YceG PF02618.11 XP_011273638.1 - 0.0036 16.3 0.2 0.0047 15.9 0.1 1.2 1 0 0 1 1 1 1 YceG-like family ERG4_ERG24 PF01222.12 XP_011273639.1 - 2.2e-166 553.6 26.8 2.5e-166 553.5 18.6 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Microvir_H PF04687.7 XP_011273640.1 - 0.034 13.1 0.7 0.053 12.5 0.5 1.3 1 0 0 1 1 1 0 Microvirus H protein (pilot protein) Proteasome PF00227.21 XP_011273641.1 - 1.3e-43 148.5 0.1 1.7e-43 148.1 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 XP_011273641.1 - 1.2e-14 53.2 0.7 2.5e-14 52.2 0.0 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Autoind_bind PF03472.10 XP_011273641.1 - 0.063 12.5 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Autoinducer binding domain Hist_deacetyl PF00850.14 XP_011273642.1 - 2.9e-80 269.8 0.0 3.8e-80 269.4 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Mannosyl_trans3 PF11051.3 XP_011273643.1 - 1.4e-87 293.5 0.0 1.8e-87 293.1 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Mannosyl_trans3 PF11051.3 XP_011273644.1 - 1.5e-85 286.8 0.0 2.1e-85 286.3 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Copper-fist PF00649.13 XP_011273646.1 - 7.2e-07 28.3 2.3 1.7e-06 27.0 1.6 1.6 1 0 0 1 1 1 1 Copper fist DNA binding domain IL10 PF00726.12 XP_011273648.1 - 0.086 12.1 0.2 1 8.6 0.1 2.2 1 1 0 1 1 1 0 Interleukin 10 RNase_HII PF01351.13 XP_011273648.1 - 0.09 12.4 0.4 0.13 11.8 0.3 1.2 1 0 0 1 1 1 0 Ribonuclease HII Sugar_tr PF00083.19 XP_011273649.1 - 1.3e-88 297.5 25.4 1.6e-88 297.3 17.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 XP_011273649.1 - 1.6e-28 99.4 44.0 1.1e-24 86.8 11.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily GerA PF03323.8 XP_011273649.1 - 3.9 5.4 7.9 7.9 4.4 5.5 1.4 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein Acyltransferase PF01553.16 XP_011273650.1 - 5.7e-11 41.9 0.0 4.6e-10 39.0 0.0 2.2 1 1 0 1 1 1 1 Acyltransferase FYVE PF01363.16 XP_011273651.1 - 1.1e-14 54.0 8.1 3e-14 52.6 5.6 1.8 1 0 0 1 1 1 1 FYVE zinc finger FGGY_C PF02782.11 XP_011273652.1 - 1.2e-58 198.0 0.1 2.4e-58 197.0 0.0 1.5 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 XP_011273652.1 - 3.6e-48 164.0 2.0 5.4e-41 140.5 0.2 2.6 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Stimulus_sens_1 PF13756.1 XP_011273652.1 - 0.18 12.1 0.1 0.87 9.9 0.0 2.1 2 0 0 2 2 2 0 Stimulus-sensing domain STT3 PF02516.9 XP_011273654.1 - 6.4e-137 457.4 40.3 6.6e-133 444.1 26.7 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit DUF3753 PF12575.3 XP_011273654.1 - 0.58 9.9 5.8 27 4.6 0.5 4.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3753) Clathrin_bdg PF15045.1 XP_011273656.1 - 0.00026 20.4 0.0 0.00062 19.2 0.0 1.6 1 0 0 1 1 1 1 Clathrin-binding box of Aftiphilin, vesicle trafficking Effector_1 PF04518.7 XP_011273656.1 - 1.5 7.7 11.5 0.027 13.4 1.0 2.2 2 0 0 2 2 2 0 Effector from type III secretion system Fungal_trans PF04082.13 XP_011273657.1 - 2.5e-22 78.9 2.4 6.9e-22 77.5 1.6 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 XP_011273657.1 - 2.4e-08 33.7 10.3 2.4e-08 33.7 7.1 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PALP PF00291.20 XP_011273658.1 - 5.6e-56 190.0 0.0 6.5e-56 189.7 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Abhydrolase_6 PF12697.2 XP_011273661.1 - 7e-20 71.8 0.0 8.7e-20 71.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 XP_011273661.1 - 1.2e-10 41.2 0.0 2.5e-10 40.2 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 XP_011273661.1 - 2e-09 37.3 0.0 2.6e-08 33.7 0.0 1.9 1 1 0 2 2 2 1 alpha/beta hydrolase fold PGAP1 PF07819.8 XP_011273661.1 - 3.6e-08 33.2 0.1 7.8e-08 32.1 0.0 1.6 2 0 0 2 2 2 1 PGAP1-like protein DUF915 PF06028.6 XP_011273661.1 - 1.6e-07 30.6 0.4 0.00088 18.4 0.0 2.4 1 1 1 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF915) DUF2048 PF09752.4 XP_011273661.1 - 0.00043 19.2 0.0 0.0036 16.2 0.0 2.0 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2048) Thioesterase PF00975.15 XP_011273661.1 - 0.0097 16.1 0.0 0.023 14.9 0.0 1.6 2 0 0 2 2 2 1 Thioesterase domain DUF676 PF05057.9 XP_011273661.1 - 0.035 13.4 0.0 0.061 12.5 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) FSH1 PF03959.8 XP_011273661.1 - 0.065 12.6 0.4 4.3 6.7 0.1 2.4 1 1 1 2 2 2 0 Serine hydrolase (FSH1) Lipase_3 PF01764.20 XP_011273661.1 - 0.065 12.8 0.0 0.15 11.6 0.0 1.6 2 0 0 2 2 2 0 Lipase (class 3) DLH PF01738.13 XP_011273661.1 - 0.082 12.1 0.0 0.56 9.4 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family CTP_transf_2 PF01467.21 XP_011273662.1 - 3.8e-16 59.5 0.0 4.2e-13 49.6 0.0 2.5 2 0 0 2 2 2 2 Cytidylyltransferase HABP4_PAI-RBP1 PF04774.10 XP_011273665.1 - 5.4e-05 23.6 3.1 8.3e-05 23.0 1.9 1.6 1 1 0 1 1 1 1 Hyaluronan / mRNA binding family F-box PF00646.28 XP_011273666.1 - 0.00031 20.3 0.0 0.0012 18.4 0.0 2.0 1 0 0 1 1 1 1 F-box domain AcylCoA_dehyd_C PF12186.3 XP_011273668.1 - 3.9 7.3 12.6 0.9 9.4 0.3 3.8 4 0 0 4 4 4 0 Acyl-CoA dehydrogenase C terminal ATE_C PF04377.10 XP_011273669.1 - 1.1e-41 141.8 2.5 2.2e-41 140.9 1.7 1.5 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 XP_011273669.1 - 4.2e-26 90.5 3.4 2.3e-25 88.2 2.0 2.4 2 1 0 2 2 2 1 Arginine-tRNA-protein transferase, N terminus HSCB_C PF07743.8 XP_011273670.1 - 7.5e-16 58.3 4.6 1.4e-15 57.4 3.2 1.5 1 0 0 1 1 1 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 XP_011273670.1 - 7.3e-09 35.2 4.4 1.3e-08 34.4 0.5 2.6 2 1 1 3 3 3 1 DnaJ domain GrpE PF01025.14 XP_011273670.1 - 0.16 11.4 6.0 0.22 11.0 4.1 1.2 1 0 0 1 1 1 0 GrpE CK_II_beta PF01214.13 XP_011273671.1 - 1.2e-72 243.3 0.0 1.6e-72 242.9 0.0 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit RNA_pol_3_Rpc31 PF11705.3 XP_011273671.1 - 0.027 14.4 5.9 0.035 14.0 3.8 1.4 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 AF1Q PF15017.1 XP_011273671.1 - 0.53 10.2 8.0 0.94 9.4 5.5 1.4 1 0 0 1 1 1 0 Drug resistance and apoptosis regulator DUF2457 PF10446.4 XP_011273671.1 - 9.2 4.8 12.4 12 4.5 8.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CHD5 PF04420.9 XP_011273672.1 - 5.5e-41 139.9 5.9 6.7e-41 139.6 4.1 1.1 1 0 0 1 1 1 1 CHD5-like protein V-SNARE PF05008.10 XP_011273672.1 - 0.029 14.5 0.3 0.049 13.8 0.2 1.4 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus DivIC PF04977.10 XP_011273672.1 - 0.056 12.9 0.6 0.16 11.4 0.4 1.7 1 0 0 1 1 1 0 Septum formation initiator DUF3635 PF12330.3 XP_011273673.1 - 1.7e-13 50.4 2.0 9.8e-13 48.0 1.4 2.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3635) Peptidase_M49 PF03571.10 XP_011273676.1 - 7.9e-236 783.4 3.3 1.1e-235 782.9 2.3 1.2 1 0 0 1 1 1 1 Peptidase family M49 E1_DerP2_DerF2 PF02221.10 XP_011273677.1 - 7.3e-25 87.7 0.1 8.9e-25 87.4 0.1 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 XP_011273677.1 - 0.00073 19.5 0.1 0.0044 17.0 0.1 1.9 1 1 0 1 1 1 1 ML-like domain DUF4313 PF14190.1 XP_011273677.1 - 0.14 11.9 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4313) PLA2_B PF01735.13 XP_011273678.1 - 1.2e-200 666.8 0.3 1.4e-200 666.6 0.2 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain IBR PF01485.16 XP_011273678.1 - 0.048 13.5 5.3 0.12 12.2 3.7 1.6 1 0 0 1 1 1 0 IBR domain PLA2_B PF01735.13 XP_011273679.1 - 6.4e-204 677.6 1.2 7.5e-204 677.4 0.9 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain IBR PF01485.16 XP_011273679.1 - 0.0073 16.1 2.7 0.015 15.1 1.9 1.4 1 0 0 1 1 1 1 IBR domain OPT PF03169.10 XP_011273680.1 - 2.4e-157 525.1 39.5 3.1e-157 524.7 27.4 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein INO80_Ies4 PF08193.6 XP_011273681.1 - 6e-08 32.8 19.7 6e-08 32.8 13.7 2.3 1 1 1 2 2 2 1 INO80 complex subunit Ies4 Pol_alpha_B_N PF08418.5 XP_011273681.1 - 0.0013 18.3 10.3 0.0013 18.3 7.1 1.5 2 0 0 2 2 2 1 DNA polymerase alpha subunit B N-terminal DUF566 PF04484.7 XP_011273681.1 - 7.6 5.9 10.1 13 5.1 7.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF566) SWIRM PF04433.12 XP_011273682.1 - 3.2e-07 30.3 2.0 1.8e-06 27.9 0.2 2.5 2 0 0 2 2 2 1 SWIRM domain DUF1708 PF08101.6 XP_011273683.1 - 1.6e-131 439.0 5.9 1e-130 436.3 4.1 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF1708) ATP11 PF06644.6 XP_011273684.1 - 6.1e-83 278.3 0.7 7.3e-83 278.1 0.5 1.0 1 0 0 1 1 1 1 ATP11 protein DUF755 PF05501.6 XP_011273684.1 - 0.084 12.9 0.6 0.16 12.0 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) PDT PF00800.13 XP_011273685.1 - 3.1e-32 111.6 0.4 5.2e-32 110.8 0.3 1.4 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.20 XP_011273685.1 - 5.3e-08 32.1 0.0 1.4e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 ACT domain zf-rbx1 PF12678.2 XP_011273686.1 - 1.1e-17 63.8 6.4 1.6e-17 63.3 4.5 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 XP_011273686.1 - 1.7e-05 24.5 4.5 2.3e-05 24.1 3.1 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger YukC PF10140.4 XP_011273686.1 - 0.028 12.9 0.3 0.034 12.7 0.2 1.0 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC THAP PF05485.7 XP_011273686.1 - 0.06 13.5 2.5 0.081 13.1 1.7 1.2 1 0 0 1 1 1 0 THAP domain Med7 PF05983.6 XP_011273687.1 - 2.8e-58 196.2 4.3 2.8e-58 196.2 3.0 1.4 2 0 0 2 2 2 1 MED7 protein Med4 PF10018.4 XP_011273687.1 - 0.0076 15.6 5.7 0.019 14.3 3.9 1.7 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 Rsa3 PF14615.1 XP_011273688.1 - 2.8e-19 68.1 0.2 2.8e-19 68.1 0.1 1.8 2 0 0 2 2 2 1 Ribosome-assembly protein 3 CMV_1a PF12467.3 XP_011273688.1 - 0.048 14.0 8.5 0.073 13.4 5.9 1.2 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family DUF966 PF06136.8 XP_011273688.1 - 0.12 11.7 8.0 0.13 11.6 5.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) SR-25 PF10500.4 XP_011273688.1 - 0.19 11.1 21.1 0.28 10.6 14.7 1.4 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Myc_N PF01056.13 XP_011273688.1 - 0.33 10.0 8.0 0.4 9.7 5.6 1.2 1 0 0 1 1 1 0 Myc amino-terminal region DUF755 PF05501.6 XP_011273688.1 - 1.1 9.2 14.5 2.6 8.1 10.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF755) DUF2151 PF10221.4 XP_011273688.1 - 1.3 7.0 9.5 1.6 6.8 6.6 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator CDC45 PF02724.9 XP_011273688.1 - 3.2 5.6 13.3 3.4 5.5 9.2 1.1 1 0 0 1 1 1 0 CDC45-like protein CENP-B_dimeris PF09026.5 XP_011273688.1 - 4.8 7.4 11.2 9.2 6.5 7.7 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain LAT PF15234.1 XP_011273688.1 - 5.3 6.4 9.6 6 6.2 6.6 1.3 1 1 0 1 1 1 0 Linker for activation of T-cells NPR3 PF03666.8 XP_011273688.1 - 5.5 5.4 9.5 6.8 5.1 6.6 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Pap_E4 PF02711.9 XP_011273688.1 - 5.9 7.7 8.6 7 7.5 5.4 1.5 1 1 0 1 1 1 0 E4 protein DDHD PF02862.12 XP_011273688.1 - 6.2 6.5 8.6 8 6.1 5.9 1.2 1 0 0 1 1 1 0 DDHD domain VIT1 PF01988.14 XP_011273689.1 - 6.3e-60 202.2 2.9 7.5e-60 202.0 2.0 1.1 1 0 0 1 1 1 1 VIT family Apolipoprotein PF01442.13 XP_011273692.1 - 0.00013 21.5 9.9 0.00024 20.6 6.9 1.5 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF883 PF05957.8 XP_011273692.1 - 0.0021 18.4 14.1 0.0057 17.0 7.0 2.1 1 1 1 2 2 2 2 Bacterial protein of unknown function (DUF883) ISG65-75 PF11727.3 XP_011273692.1 - 0.0046 16.0 17.3 0.0052 15.8 12.0 1.1 1 0 0 1 1 1 1 Invariant surface glycoprotein FH2 PF02181.18 XP_011273692.1 - 0.01 14.7 10.0 0.013 14.4 6.9 1.2 1 0 0 1 1 1 0 Formin Homology 2 Domain TMPIT PF07851.8 XP_011273692.1 - 0.079 12.0 7.0 0.094 11.7 4.8 1.0 1 0 0 1 1 1 0 TMPIT-like protein Rsd_AlgQ PF04353.8 XP_011273692.1 - 0.095 12.4 1.5 0.11 12.2 1.0 1.3 1 0 0 1 1 1 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ DUF4449 PF14613.1 XP_011273692.1 - 0.15 12.0 13.2 0.17 11.7 9.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4449) DUF3810 PF12725.2 XP_011273692.1 - 0.24 10.2 4.4 0.29 10.0 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) DUF4407 PF14362.1 XP_011273692.1 - 0.25 10.2 12.6 0.29 10.0 8.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) OmpH PF03938.9 XP_011273692.1 - 0.27 11.1 15.4 0.34 10.8 10.7 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Prominin PF05478.6 XP_011273692.1 - 0.31 8.5 7.1 0.29 8.5 4.9 1.1 1 0 0 1 1 1 0 Prominin HisKA_3 PF07730.8 XP_011273692.1 - 0.4 11.0 6.1 2.6 8.4 0.8 2.3 1 1 1 2 2 2 0 Histidine kinase YtxH PF12732.2 XP_011273692.1 - 0.41 11.0 23.3 1.4e+02 2.9 16.2 2.4 1 1 0 1 1 1 0 YtxH-like protein Phasin PF05597.6 XP_011273692.1 - 0.45 10.2 18.7 0.84 9.3 5.6 2.2 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Sigma70_ner PF04546.8 XP_011273692.1 - 0.46 10.0 15.7 0.54 9.8 10.9 1.0 1 0 0 1 1 1 0 Sigma-70, non-essential region SBP_bac_7 PF03480.8 XP_011273692.1 - 0.51 9.3 7.0 0.54 9.3 4.9 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein, family 7 DUF763 PF05559.6 XP_011273692.1 - 0.66 8.8 6.7 0.75 8.6 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF763) MT0933_antitox PF14013.1 XP_011273692.1 - 0.98 9.5 19.2 3.3 7.8 0.2 2.7 1 1 2 3 3 3 0 MT0933-like antitoxin protein ATP-synt_B PF00430.13 XP_011273692.1 - 1 9.1 20.5 2.2 8.0 13.0 1.9 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) DUF4175 PF13779.1 XP_011273692.1 - 1.1 6.8 10.6 1.3 6.5 7.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF4629 PF15442.1 XP_011273692.1 - 1.2 9.2 12.8 1.6 8.8 8.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4629) DUF3807 PF12720.2 XP_011273692.1 - 1.6 8.8 16.4 1.9 8.6 11.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) GOLD_2 PF13897.1 XP_011273692.1 - 1.7 8.8 6.3 2.2 8.5 4.4 1.3 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking LMBR1 PF04791.11 XP_011273692.1 - 1.7 7.1 10.3 1.8 7.0 7.2 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein IncA PF04156.9 XP_011273692.1 - 1.8 8.1 8.9 2 8.0 6.2 1.1 1 0 0 1 1 1 0 IncA protein Mitofilin PF09731.4 XP_011273692.1 - 1.8 7.0 21.8 2 6.9 15.1 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein ApoO PF09769.4 XP_011273692.1 - 1.9 8.1 5.7 6.6 6.4 3.7 1.8 1 1 0 1 1 1 0 Apolipoprotein O FGF-BP1 PF06473.7 XP_011273692.1 - 2.3 7.7 13.2 2.7 7.5 9.1 1.1 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) DivIVA PF05103.8 XP_011273692.1 - 2.4 8.1 17.5 3.6 7.6 12.1 1.5 1 1 0 1 1 1 0 DivIVA protein Mnd1 PF03962.10 XP_011273692.1 - 2.7 7.6 12.1 3.3 7.3 8.4 1.2 1 0 0 1 1 1 0 Mnd1 family AAA_13 PF13166.1 XP_011273692.1 - 3 6.1 13.6 3.1 6.1 9.4 1.0 1 0 0 1 1 1 0 AAA domain Hid1 PF12722.2 XP_011273692.1 - 3.2 5.3 7.7 3.4 5.2 5.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein KfrA_N PF11740.3 XP_011273692.1 - 3.3 8.1 18.2 4.4 7.7 8.1 2.0 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term Effector_1 PF04518.7 XP_011273692.1 - 4.7 6.0 9.3 5.2 5.9 6.5 1.1 1 0 0 1 1 1 0 Effector from type III secretion system DUF2894 PF11445.3 XP_011273692.1 - 4.8 7.3 9.5 5.6 7.1 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) MMPL PF03176.10 XP_011273692.1 - 5.1 5.7 8.8 5.7 5.5 6.1 1.1 1 0 0 1 1 1 0 MMPL family CENP-I PF07778.6 XP_011273692.1 - 5.5 5.0 7.1 6.6 4.7 4.9 1.0 1 0 0 1 1 1 0 Mis6 Snapin_Pallidin PF14712.1 XP_011273692.1 - 5.7 7.3 7.5 5 7.4 4.3 1.6 1 1 1 2 2 2 0 Snapin/Pallidin Transposase_22 PF02994.9 XP_011273692.1 - 5.8 5.2 13.4 3.7 5.9 8.0 1.4 1 1 1 2 2 2 0 L1 transposable element CDC45 PF02724.9 XP_011273692.1 - 6.1 4.7 12.8 6.6 4.6 8.9 1.0 1 0 0 1 1 1 0 CDC45-like protein BTV_NS2 PF04514.7 XP_011273692.1 - 6.9 5.4 12.5 7.8 5.2 8.6 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 RR_TM4-6 PF06459.7 XP_011273692.1 - 8.5 6.1 17.4 9.9 5.9 12.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2890 PF11081.3 XP_011273692.1 - 9.3 6.2 15.8 11 6.0 10.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) DUF3449 PF11931.3 XP_011273692.1 - 10 5.6 11.6 12 5.3 8.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) Rcd1 PF04078.8 XP_011273693.1 - 1.9e-128 426.8 0.5 2.5e-128 426.4 0.3 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Adaptin_N PF01602.15 XP_011273694.1 - 4e-103 345.5 20.2 5.4e-103 345.0 14.0 1.2 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 XP_011273694.1 - 2.1e-52 176.9 5.3 2.1e-52 176.9 3.7 1.8 2 0 0 2 2 2 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 XP_011273694.1 - 5.9e-12 45.7 0.3 0.00071 19.8 0.0 5.4 3 2 1 4 4 4 2 HEAT repeats HEAT PF02985.17 XP_011273694.1 - 0.1 12.7 7.8 61 4.1 0.0 6.6 8 0 0 8 8 8 0 HEAT repeat AFT PF08731.6 XP_011273695.1 - 1.9e-24 86.0 2.6 1.9e-24 86.0 1.8 2.0 2 0 0 2 2 2 1 Transcription factor AFT DBD_Tnp_Mut PF03108.10 XP_011273695.1 - 0.0011 18.4 1.4 0.62 9.6 0.0 2.7 3 0 0 3 3 3 2 MuDR family transposase FAR1 PF03101.10 XP_011273695.1 - 0.069 13.6 0.2 0.15 12.5 0.2 1.6 1 0 0 1 1 1 0 FAR1 DNA-binding domain zf-BED PF02892.10 XP_011273696.1 - 0.016 14.9 0.1 0.039 13.6 0.0 1.7 1 0 0 1 1 1 0 BED zinc finger GATA PF00320.22 XP_011273696.1 - 0.025 13.9 0.4 0.066 12.5 0.3 1.8 1 0 0 1 1 1 0 GATA zinc finger Glycos_transf_2 PF00535.21 XP_011273697.1 - 1.1e-28 99.9 0.1 1.7e-28 99.3 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 XP_011273697.1 - 2e-10 40.8 0.0 6.7e-10 39.1 0.0 1.7 1 1 1 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 XP_011273697.1 - 4.7e-05 22.6 0.0 6.3e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Spermine_synth PF01564.12 XP_011273697.1 - 0.042 12.7 0.1 0.065 12.1 0.0 1.3 1 0 0 1 1 1 0 Spermine/spermidine synthase mRNA_triPase PF02940.10 XP_011273698.1 - 4.4e-44 150.8 6.7 9.6e-44 149.6 4.6 1.6 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain DUF4452 PF14618.1 XP_011273699.1 - 5.5e-22 78.3 6.4 5.5e-22 78.3 4.4 2.7 1 1 2 3 3 3 1 Domain of unknown function (DUF4452) Reprolysin_3 PF13582.1 XP_011273699.1 - 0.23 11.9 6.8 0.49 10.9 4.6 1.6 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like zf-C2H2 PF00096.21 XP_011273700.1 - 2.1e-09 37.1 13.2 5.2e-05 23.3 2.3 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 XP_011273700.1 - 1.8e-08 34.2 3.2 1.8e-08 34.2 2.2 3.9 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 XP_011273700.1 - 2.9e-05 24.0 12.4 0.00051 20.1 1.7 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 XP_011273700.1 - 0.0021 17.8 1.3 0.0021 17.8 0.9 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger Ogr_Delta PF04606.7 XP_011273700.1 - 0.0033 17.0 0.1 0.011 15.3 0.1 1.9 1 0 0 1 1 1 1 Ogr/Delta-like zinc finger zf-C2H2_jaz PF12171.3 XP_011273700.1 - 0.0055 16.8 1.5 0.0055 16.8 1.0 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding COesterase PF00135.23 XP_011273701.1 - 1.8e-103 347.0 1.8 2.4e-103 346.6 1.3 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 XP_011273701.1 - 3.1e-05 23.6 0.1 0.0097 15.4 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 XP_011273701.1 - 0.0013 17.9 0.0 0.0028 16.8 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 XP_011273701.1 - 0.089 12.5 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Exo_endo_phos PF03372.18 XP_011273702.1 - 7.2e-14 52.3 0.8 9.1e-14 51.9 0.5 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Epimerase PF01370.16 XP_011273703.1 - 2e-16 60.1 0.0 4.5e-16 58.9 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 XP_011273703.1 - 2.1e-12 46.3 0.0 2.9e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 XP_011273703.1 - 5.8e-09 35.2 0.0 3.3e-08 32.7 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 XP_011273703.1 - 8.5e-08 32.2 0.0 2.5e-07 30.7 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.1 XP_011273703.1 - 1.7e-07 31.4 0.3 4.3e-07 30.1 0.2 1.7 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 XP_011273703.1 - 3.7e-07 29.9 0.0 7.9e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 XP_011273703.1 - 0.037 13.2 0.1 0.069 12.4 0.1 1.5 1 1 0 1 1 1 0 NmrA-like family Epimerase PF01370.16 XP_011273704.1 - 1.1e-18 67.5 0.0 1.9e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 XP_011273704.1 - 3.3e-12 45.6 0.0 4.3e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 XP_011273704.1 - 2.5e-10 40.6 1.1 7.3e-10 39.1 0.8 1.8 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 XP_011273704.1 - 4.6e-09 35.5 0.1 2.7e-08 33.0 0.1 1.9 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 XP_011273704.1 - 5e-09 36.3 0.7 1.3e-08 34.9 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 XP_011273704.1 - 4.2e-08 33.0 0.1 1.5e-07 31.2 0.0 1.9 2 0 0 2 2 2 1 KR domain NmrA PF05368.8 XP_011273704.1 - 1.1e-05 24.7 1.1 3.2e-05 23.3 0.7 1.9 1 1 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.10 XP_011273704.1 - 0.00016 20.6 0.0 0.00042 19.3 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short_C2 PF13561.1 XP_011273704.1 - 0.023 14.4 0.2 0.057 13.1 0.1 1.8 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase F420_oxidored PF03807.12 XP_011273704.1 - 0.075 13.4 0.2 0.67 10.4 0.0 2.6 4 0 0 4 4 4 0 NADP oxidoreductase coenzyme F420-dependent Exo_endo_phos PF03372.18 XP_011273705.1 - 1.5e-12 47.9 2.3 1.8e-12 47.7 1.6 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ldh_1_N PF00056.18 XP_011273706.1 - 3.7e-45 153.2 0.1 5.8e-45 152.5 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 XP_011273706.1 - 1.6e-40 138.6 0.0 2.2e-40 138.2 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 XP_011273706.1 - 0.00036 19.3 0.0 0.00077 18.2 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Mistic PF11458.3 XP_011273706.1 - 0.037 14.4 0.2 0.17 12.3 0.0 2.1 2 0 0 2 2 2 0 Membrane-integrating protein Mistic Ribosomal_L23 PF00276.15 XP_011273707.1 - 2e-21 75.6 1.7 4.2e-21 74.6 1.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L23 Ribosomal_L23eN PF03939.8 XP_011273707.1 - 4.6e-20 71.3 5.7 4.6e-20 71.3 4.0 2.3 2 1 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_S11 PF00411.14 XP_011273708.1 - 1.6e-06 28.2 0.0 3.8e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S11 MOR2-PAG1_C PF14225.1 XP_011273708.1 - 0.1 12.3 0.1 0.2 11.4 0.0 1.4 1 1 0 1 1 1 0 Cell morphogenesis C-terminal Pkinase PF00069.20 XP_011273709.1 - 8.9e-59 198.7 0.0 1e-58 198.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011273709.1 - 8e-27 93.9 0.0 1e-26 93.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 XP_011273709.1 - 0.00012 21.1 0.0 0.00018 20.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 XP_011273709.1 - 0.0033 16.4 0.0 0.0044 16.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 XP_011273709.1 - 0.0041 16.8 0.0 0.0065 16.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 XP_011273709.1 - 0.013 15.0 0.0 0.02 14.4 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase UPF0220 PF05255.6 XP_011273710.1 - 6e-70 233.7 4.1 6.8e-70 233.6 2.8 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Nuc_sug_transp PF04142.10 XP_011273711.1 - 2.3e-14 53.1 0.9 5.7e-14 51.8 0.6 1.7 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 XP_011273711.1 - 3.5e-14 52.4 14.8 4.6e-14 52.0 10.3 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 XP_011273711.1 - 9.6e-08 32.1 36.2 0.00042 20.3 6.7 3.3 3 2 1 4 4 4 3 EamA-like transporter family EmrE PF13536.1 XP_011273711.1 - 1.1e-05 25.5 1.3 1.1e-05 25.5 0.9 3.0 2 1 0 2 2 2 1 Multidrug resistance efflux transporter TPT PF03151.11 XP_011273711.1 - 7e-05 22.5 22.5 0.011 15.3 9.1 2.3 2 0 0 2 2 2 2 Triose-phosphate Transporter family ETRAMP PF09716.5 XP_011273711.1 - 6.7 6.7 9.4 1.3e+02 2.6 5.4 3.4 3 1 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) DUF4210 PF13915.1 XP_011273712.1 - 4.9e-07 29.9 0.0 1.1e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.1 XP_011273712.1 - 1.6e-05 24.6 0.4 3.4e-05 23.6 0.3 1.5 1 0 0 1 1 1 1 Chromosome segregation during meiosis zf-RING_5 PF14634.1 XP_011273713.1 - 0.00028 20.5 1.6 0.0015 18.1 0.1 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 XP_011273713.1 - 0.0012 18.5 0.1 0.0036 16.9 0.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 XP_011273713.1 - 0.0051 16.8 0.2 0.0051 16.8 0.1 2.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 XP_011273713.1 - 0.044 13.5 1.1 0.18 11.5 0.7 2.1 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 XP_011273713.1 - 0.1 12.4 0.5 0.1 12.4 0.3 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING RPAP2_Rtr1 PF04181.8 XP_011273713.1 - 9.5 6.3 8.0 1.7 8.8 1.8 2.4 2 0 0 2 2 2 0 Rtr1/RPAP2 family Fibrillarin PF01269.12 XP_011273714.1 - 5.9e-108 359.0 0.0 7.1e-108 358.8 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 XP_011273714.1 - 1.4e-05 24.6 0.0 3.1e-05 23.5 0.0 1.4 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 XP_011273714.1 - 0.059 12.9 0.0 0.093 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Mpv17_PMP22 PF04117.7 XP_011273715.1 - 1.6e-06 27.5 0.9 4.9e-06 26.0 0.6 1.8 1 0 0 1 1 1 1 Mpv17 / PMP22 family ATP-synt_E PF05680.7 XP_011273715.1 - 0.43 10.5 4.6 0.77 9.7 3.2 1.4 1 0 0 1 1 1 0 ATP synthase E chain SH3_1 PF00018.23 XP_011273716.1 - 7.4e-09 34.8 0.2 7.4e-09 34.8 0.1 2.8 3 0 0 3 3 3 1 SH3 domain SH3_9 PF14604.1 XP_011273716.1 - 1.4e-06 27.7 0.1 1.4e-06 27.7 0.1 2.2 2 0 0 2 2 2 1 Variant SH3 domain HEAT_EZ PF13513.1 XP_011273717.1 - 2.5e-32 110.5 8.3 1.6e-13 50.7 0.0 10.4 9 1 2 11 11 11 6 HEAT-like repeat HEAT PF02985.17 XP_011273717.1 - 2e-30 102.1 12.9 0.0007 19.4 0.0 12.0 13 0 0 13 13 13 5 HEAT repeat HEAT_2 PF13646.1 XP_011273717.1 - 3.9e-29 100.7 0.2 3.5e-06 27.2 0.0 8.0 5 3 2 8 8 8 7 HEAT repeats Vac14_Fab1_bd PF12755.2 XP_011273717.1 - 7.2e-11 42.3 0.7 0.029 14.7 0.0 6.1 4 3 3 7 7 6 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 XP_011273717.1 - 4.8e-09 36.3 16.2 0.0017 18.2 0.4 5.9 5 1 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 XP_011273717.1 - 5.7e-09 34.8 6.0 0.023 13.0 0.0 4.7 4 2 1 5 5 5 3 Adaptin N terminal region IBN_N PF03810.14 XP_011273717.1 - 5.2e-08 32.6 0.9 1.2e-06 28.2 0.0 3.9 5 0 0 5 5 5 1 Importin-beta N-terminal domain Arm PF00514.18 XP_011273717.1 - 1.5e-06 27.8 8.1 5.1 7.0 0.0 7.8 8 0 0 8 8 8 3 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.11 XP_011273717.1 - 0.006 16.9 0.2 57 4.6 0.0 4.8 4 0 0 4 4 3 0 PBS lyase HEAT-like repeat HisK_N PF09385.5 XP_011273717.1 - 0.008 15.7 0.5 4.4 6.9 0.0 2.8 2 0 0 2 2 2 2 Histidine kinase N terminal DUF4101 PF13355.1 XP_011273717.1 - 0.094 13.1 2.1 0.39 11.1 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4101) DUF3665 PF12427.3 XP_011273717.1 - 0.12 11.7 0.0 0.31 10.4 0.0 1.7 1 0 0 1 1 1 0 Branched-chain amino acid aminotransferase Vitellogenin_N PF01347.17 XP_011273717.1 - 0.19 9.9 2.9 0.12 10.5 0.0 1.9 2 1 0 2 2 2 0 Lipoprotein amino terminal region MMS19_C PF12460.3 XP_011273717.1 - 0.25 10.0 19.6 0.078 11.6 0.1 5.0 5 2 2 7 7 7 0 RNAPII transcription regulator C-terminal Xpo1 PF08389.7 XP_011273717.1 - 0.56 10.1 15.8 0.71 9.7 0.0 6.2 5 2 2 7 7 7 0 Exportin 1-like protein Amidohydro_1 PF01979.15 XP_011273718.1 - 1.9e-36 126.3 0.0 5.7e-22 78.8 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 XP_011273718.1 - 6.9e-26 91.8 0.0 6.1e-14 52.6 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 XP_011273718.1 - 1.7e-09 37.4 0.2 3.3e-06 26.5 0.0 2.5 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 XP_011273718.1 - 2.1e-09 37.0 0.8 7.9e-09 35.2 0.0 2.5 2 0 0 2 2 2 1 Amidohydrolase EMP24_GP25L PF01105.19 XP_011273719.1 - 1.1e-41 142.5 0.2 1.2e-41 142.3 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Pkinase PF00069.20 XP_011273720.1 - 4e-40 137.6 0.0 4e-38 131.0 0.0 3.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011273720.1 - 2.4e-13 49.7 0.0 8.9e-10 38.0 0.0 3.2 3 1 0 3 3 3 2 Protein tyrosine kinase Git3 PF11710.3 XP_011273721.1 - 2.5e-65 219.8 18.3 2.5e-65 219.8 12.7 1.8 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 XP_011273721.1 - 5e-20 71.0 0.5 5e-20 71.0 0.4 2.6 3 0 0 3 3 3 1 G protein-coupled glucose receptor regulating Gpa2 C-term FAM219A PF15260.1 XP_011273721.1 - 0.032 14.5 0.6 0.062 13.6 0.4 1.4 1 0 0 1 1 1 0 Protein family FAM219A TMEM107 PF14995.1 XP_011273721.1 - 0.76 9.9 6.5 0.082 13.0 0.6 2.2 3 0 0 3 3 3 0 Transmembrane protein VPS9 PF02204.13 XP_011273722.1 - 1.7e-19 69.7 1.8 4.7e-19 68.3 1.2 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain SH3_1 PF00018.23 XP_011273724.1 - 7.8e-26 89.2 0.0 1.8e-14 52.8 0.0 2.7 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 XP_011273724.1 - 9.2e-15 53.9 0.5 9.3e-09 34.7 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.19 XP_011273724.1 - 1e-12 47.8 0.0 2.2e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 PX domain SH3_2 PF07653.12 XP_011273724.1 - 5.6e-12 44.9 0.4 6.6e-10 38.3 0.0 2.7 3 0 0 3 3 3 1 Variant SH3 domain PB1 PF00564.19 XP_011273724.1 - 3.7e-05 23.2 0.6 8.8e-05 22.1 0.4 1.6 1 0 0 1 1 1 1 PB1 domain GDPD PF03009.12 XP_011273725.1 - 1.9e-27 96.3 2.4 1.5e-26 93.4 1.0 2.4 2 1 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 XP_011273725.1 - 3.4e-06 27.0 0.0 8.6e-06 25.7 0.0 1.8 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family PQ-loop PF04193.9 XP_011273726.1 - 4.3e-40 135.0 18.2 4.1e-21 74.2 1.7 3.0 3 0 0 3 3 3 2 PQ loop repeat MtN3_slv PF03083.11 XP_011273726.1 - 0.37 10.6 5.4 0.55 10.1 0.1 2.7 2 1 0 2 2 2 0 Sugar efflux transporter for intercellular exchange DUF4234 PF14018.1 XP_011273726.1 - 1 9.1 0.0 1 9.1 0.0 3.2 3 2 1 4 4 4 0 Domain of unknown function (DUF4234) MutS_V PF00488.16 XP_011273727.1 - 6.1e-94 313.8 0.4 1e-93 313.0 0.3 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 XP_011273727.1 - 1.1e-31 110.2 3.7 1.1e-31 110.2 2.6 1.8 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.12 XP_011273727.1 - 2.2e-17 63.3 0.0 2.2e-17 63.3 0.0 2.6 4 0 0 4 4 4 1 MutS domain II MutS_IV PF05190.13 XP_011273727.1 - 2.2e-16 59.7 2.8 5.8e-16 58.4 0.5 2.9 2 0 0 2 2 2 1 MutS family domain IV MutS_I PF01624.15 XP_011273727.1 - 4.6e-09 36.2 0.3 2.1e-08 34.2 0.0 2.2 2 0 0 2 2 2 1 MutS domain I Aldo_ket_red PF00248.16 XP_011273728.1 - 7.1e-38 130.0 0.1 8.7e-38 129.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF4455 PF14643.1 XP_011273728.1 - 0.56 8.7 1.5 0.47 9.0 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4455) NUDIX PF00293.23 XP_011273729.1 - 9.1e-14 51.2 0.0 1.5e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain zf-NADH-PPase PF09297.6 XP_011273729.1 - 1.6e-06 27.5 0.3 2.6e-06 26.8 0.2 1.3 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain NUDIX-like PF09296.6 XP_011273729.1 - 0.00013 22.2 0.0 0.00027 21.2 0.0 1.6 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain Metallothio_5 PF02067.10 XP_011273729.1 - 0.6 10.1 4.7 0.89 9.6 3.2 1.2 1 0 0 1 1 1 0 Metallothionein family 5 Pkinase PF00069.20 XP_011273730.1 - 1.3e-37 129.4 0.0 2.5e-37 128.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011273730.1 - 5.2e-12 45.3 0.0 7.4e-12 44.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 XP_011273730.1 - 3.1e-06 27.0 0.0 0.0024 17.6 0.0 2.4 2 0 0 2 2 2 2 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 XP_011273730.1 - 0.082 11.6 0.1 0.12 11.1 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Brr6_like_C_C PF10104.4 XP_011273731.1 - 3.2e-49 165.9 1.0 5.5e-49 165.1 0.7 1.4 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain PBP1_TM PF14812.1 XP_011273731.1 - 0.26 11.6 12.4 0.076 13.3 5.1 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Aldo_ket_red PF00248.16 XP_011273732.1 - 1.2e-45 155.5 0.0 1.4e-45 155.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MRP-L27 PF09809.4 XP_011273732.1 - 0.0088 15.6 0.0 0.02 14.5 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 RAI1 PF08652.6 XP_011273733.1 - 2.4e-29 100.9 0.0 7.1e-29 99.3 0.0 1.9 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease tRNA-synt_1c PF00749.16 XP_011273734.1 - 2.9e-112 374.3 0.0 3.7e-112 374.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 XP_011273734.1 - 1.2e-42 145.5 0.5 2.5e-42 144.4 0.3 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 XP_011273734.1 - 1.6e-08 34.9 0.0 6.5e-08 32.9 0.0 2.1 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 XP_011273734.1 - 6.4e-06 26.0 0.1 2.3e-05 24.2 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 XP_011273734.1 - 0.0011 18.7 0.0 0.0026 17.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF155 PF02582.9 XP_011273735.1 - 5.4e-62 208.7 0.3 5.4e-62 208.7 0.2 1.9 2 0 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 SecG PF03840.9 XP_011273735.1 - 0.064 13.0 2.1 0.34 10.6 0.3 2.4 2 0 0 2 2 2 0 Preprotein translocase SecG subunit Plus-3 PF03126.13 XP_011273736.1 - 5.2e-22 77.9 0.2 3.2e-21 75.3 0.1 2.5 1 0 0 1 1 1 1 Plus-3 domain UPF0172 PF03665.8 XP_011273736.1 - 0.021 14.3 1.0 0.021 14.3 0.7 3.0 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0172) A_deamin PF02137.13 XP_011273737.1 - 4.3e-56 190.6 0.0 5.7e-56 190.2 0.0 1.2 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain Ank PF00023.25 XP_011273738.1 - 4e-15 54.7 0.0 2.6e-06 26.9 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 XP_011273738.1 - 2.3e-13 50.3 0.1 8.5e-12 45.2 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 XP_011273738.1 - 2.7e-12 46.8 0.1 1.2e-06 28.8 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 XP_011273738.1 - 8e-12 45.0 0.0 4.9e-05 23.4 0.0 4.1 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 XP_011273738.1 - 4.6e-10 38.7 0.0 0.0015 18.5 0.0 3.6 3 1 0 3 3 3 2 Ankyrin repeat IBN_N PF03810.14 XP_011273739.1 - 1.5e-05 24.8 2.4 4.1e-05 23.3 0.1 3.1 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.7 XP_011273739.1 - 0.0036 17.2 10.5 0.051 13.4 0.0 5.3 4 3 2 6 6 6 2 Exportin 1-like protein HEAT PF02985.17 XP_011273739.1 - 0.007 16.3 0.7 24 5.3 0.0 4.5 4 0 0 4 4 4 2 HEAT repeat MFS_1 PF07690.11 XP_011273740.1 - 6.8e-30 103.9 25.6 6.8e-30 103.9 15.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily ESSS PF10183.4 XP_011273740.1 - 0.75 10.2 2.1 1.7 9.0 0.9 1.9 1 1 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Fis1_TPR_C PF14853.1 XP_011273741.1 - 2.5e-27 94.4 0.7 3.7e-27 93.9 0.5 1.2 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 XP_011273741.1 - 6.3e-16 57.3 0.0 1.1e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_14 PF13428.1 XP_011273741.1 - 0.0041 17.6 0.4 0.014 15.9 0.3 1.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 XP_011273741.1 - 0.008 16.4 0.1 0.016 15.5 0.1 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_9 PF13371.1 XP_011273741.1 - 0.021 14.6 0.5 0.055 13.3 0.2 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 XP_011273741.1 - 0.027 14.3 0.3 0.071 13.0 0.1 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat IlvN PF07991.7 XP_011273741.1 - 0.08 12.3 0.0 0.33 10.2 0.0 1.8 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain DUF619 PF04768.8 XP_011273742.1 - 4.4e-53 179.1 0.2 9.4e-53 178.1 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 XP_011273742.1 - 8.7e-31 106.7 0.0 2.4e-30 105.3 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 XP_011273742.1 - 1.7e-20 73.6 0.1 3.1e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family DapB_N PF01113.15 XP_011273742.1 - 0.0047 16.8 0.0 0.012 15.5 0.0 1.7 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Methyltransf_31 PF13847.1 XP_011273743.1 - 2e-24 85.8 0.1 2.9e-24 85.3 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 XP_011273743.1 - 4.3e-16 59.4 0.0 6.5e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 XP_011273743.1 - 3.1e-07 29.9 0.0 5.3e-07 29.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 XP_011273743.1 - 1.3e-06 28.1 0.1 2e-06 27.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 XP_011273743.1 - 1.5e-06 28.5 0.0 2.3e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 XP_011273743.1 - 1.9e-06 28.2 0.0 3.3e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 XP_011273743.1 - 2.4e-06 27.5 0.0 6.1e-06 26.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 XP_011273743.1 - 5.3e-06 26.7 0.0 8.4e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 XP_011273743.1 - 1e-05 25.2 0.0 1.3e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 XP_011273743.1 - 2.7e-05 23.3 0.0 3.5e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.12 XP_011273743.1 - 0.00025 20.1 0.0 0.00048 19.2 0.0 1.5 2 0 0 2 2 2 1 Putative methyltransferase DOT1 PF08123.8 XP_011273743.1 - 0.00084 18.7 0.1 0.0022 17.3 0.0 1.6 2 0 0 2 2 2 1 Histone methylation protein DOT1 PrmA PF06325.8 XP_011273743.1 - 0.0011 18.1 0.0 0.002 17.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) AdoMet_MTase PF07757.8 XP_011273743.1 - 0.0029 17.7 0.0 0.0046 17.0 0.0 1.4 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase TehB PF03848.9 XP_011273743.1 - 0.0043 16.2 0.1 0.0065 15.6 0.1 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB MetW PF07021.7 XP_011273743.1 - 0.0048 16.2 0.0 0.0071 15.7 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_20 PF12147.3 XP_011273743.1 - 0.036 12.9 0.0 0.67 8.7 0.0 2.0 1 1 1 2 2 2 0 Putative methyltransferase PCMT PF01135.14 XP_011273743.1 - 0.037 13.5 0.0 0.046 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.13 XP_011273743.1 - 0.093 11.8 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Ran_BP1 PF00638.13 XP_011273744.1 - 7e-28 97.1 0.0 1.7e-27 95.9 0.0 1.7 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.18 XP_011273744.1 - 0.0085 15.7 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 WH1 domain Kinesin PF00225.18 XP_011273745.1 - 6.4e-52 176.3 4.0 6.4e-52 176.3 2.8 2.8 2 1 0 3 3 3 1 Kinesin motor domain TPR_MLP1_2 PF07926.7 XP_011273745.1 - 4.5 7.0 53.5 1.9 8.2 8.4 3.7 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Nup54 PF13874.1 XP_011273745.1 - 8.2 6.0 33.2 1.3 8.7 6.9 3.6 1 1 1 3 3 3 0 Nucleoporin complex subunit 54 P16-Arc PF04699.9 XP_011273746.1 - 1.7e-13 50.8 0.0 1.7e-13 50.8 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) RRM_1 PF00076.17 XP_011273747.1 - 9.2e-21 73.2 0.2 1.8e-20 72.3 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 XP_011273747.1 - 9.3e-18 63.9 0.0 1.8e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.3 XP_011273747.1 - 2.1e-13 50.3 2.7 2.1e-13 50.3 1.9 2.7 2 1 0 2 2 2 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_5 PF13893.1 XP_011273747.1 - 4.8e-10 39.1 0.0 9.5e-10 38.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 XP_011273747.1 - 0.084 12.7 0.2 0.084 12.7 0.1 2.3 3 0 0 3 3 3 0 RNA binding motif NLPC_P60 PF00877.14 XP_011273748.1 - 0.0076 16.0 0.3 0.022 14.5 0.1 1.9 1 1 1 2 2 2 1 NlpC/P60 family Fis1_TPR_C PF14853.1 XP_011273748.1 - 0.064 13.1 1.0 0.22 11.4 0.7 1.9 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat zf-RING_4 PF14570.1 XP_011273749.1 - 1.6e-15 56.4 8.8 3.6e-15 55.2 6.1 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.17 XP_011273749.1 - 9.8e-08 31.5 0.0 4.4e-07 29.4 0.0 2.2 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 XP_011273749.1 - 3e-07 30.1 1.7 1.7e-06 27.7 0.2 2.7 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Baculo_IE-1 PF05290.6 XP_011273749.1 - 4.8e-05 23.1 3.8 0.00014 21.5 2.6 1.8 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-C3HC4_3 PF13920.1 XP_011273749.1 - 0.00061 19.4 3.7 0.00061 19.4 2.5 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SET_assoc PF11767.3 XP_011273749.1 - 0.00072 18.8 0.1 0.0017 17.6 0.1 1.5 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated RRM_6 PF14259.1 XP_011273749.1 - 0.0026 17.6 0.0 0.0064 16.4 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4 PF00097.20 XP_011273749.1 - 0.0091 15.6 5.7 0.024 14.2 3.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 XP_011273749.1 - 0.12 12.2 3.7 0.25 11.1 2.6 1.6 1 0 0 1 1 1 0 Ring finger domain zf-UDP PF14569.1 XP_011273749.1 - 0.12 12.1 4.7 0.5 10.1 3.3 2.0 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C3HC4_2 PF13923.1 XP_011273749.1 - 0.17 11.8 4.9 0.45 10.5 3.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 XP_011273749.1 - 0.37 10.7 7.1 1.1 9.1 4.9 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING MCM PF00493.18 XP_011273750.1 - 4.8e-133 443.0 0.1 2.5e-131 437.3 0.0 2.1 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 XP_011273750.1 - 6.4e-27 94.4 7.5 6.4e-27 94.4 5.2 2.6 3 1 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.16 XP_011273750.1 - 4.3e-08 32.5 0.2 1.1e-05 24.6 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 XP_011273750.1 - 5.5e-07 29.4 0.0 2.6e-06 27.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 XP_011273750.1 - 0.0056 16.2 0.1 0.036 13.6 0.1 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 XP_011273750.1 - 0.074 12.5 0.1 0.42 10.0 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain Phosphorylase PF00343.15 XP_011273751.1 - 0 1068.5 0.2 0 1068.2 0.1 1.1 1 0 0 1 1 1 1 Carbohydrate phosphorylase Peptidase_S10 PF00450.17 XP_011273752.1 - 3.1e-103 346.1 0.1 4.9e-103 345.4 0.1 1.3 1 0 0 1 1 1 1 Serine carboxypeptidase DUF4366 PF14283.1 XP_011273752.1 - 0.0032 16.9 0.0 0.0062 15.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) DUF2391 PF09622.5 XP_011273753.1 - 0.012 14.7 0.1 0.021 13.9 0.1 1.3 1 0 0 1 1 1 0 Putative integral membrane protein (DUF2391) DUF2681 PF10883.3 XP_011273753.1 - 0.77 10.0 3.7 2.3 8.4 2.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Catalase PF00199.14 XP_011273754.1 - 1.1e-156 521.3 0.4 1.5e-156 520.9 0.3 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 XP_011273754.1 - 1.3e-13 50.6 0.1 9.8e-13 47.7 0.0 2.5 3 0 0 3 3 3 1 Catalase-related immune-responsive Zip PF02535.17 XP_011273755.1 - 4.1e-60 203.4 8.4 4.6e-60 203.2 5.8 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Cullin PF00888.17 XP_011273757.1 - 2.7e-38 131.9 2.2 4.2e-38 131.2 1.5 1.3 1 0 0 1 1 1 1 Cullin family APC2 PF08672.6 XP_011273757.1 - 4.3e-12 46.0 0.1 1.5e-10 41.1 0.0 2.9 2 1 0 2 2 2 1 Anaphase promoting complex (APC) subunit 2 Cullin_binding PF03556.10 XP_011273758.1 - 6.8e-20 71.3 5.6 6.8e-20 71.3 3.9 2.1 1 1 1 2 2 2 1 Cullin binding UBA_4 PF14555.1 XP_011273758.1 - 6.3e-09 35.2 0.6 1.2e-08 34.2 0.1 1.8 2 0 0 2 2 2 1 UBA-like domain CUE PF02845.11 XP_011273758.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 CUE domain Scm3 PF10384.4 XP_011273758.1 - 0.38 10.2 3.3 0.18 11.3 0.2 2.0 2 0 0 2 2 2 0 Centromere protein Scm3 TFIID_20kDa PF03847.8 XP_011273759.1 - 1.4e-30 105.4 0.2 2.5e-30 104.5 0.1 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.18 XP_011273759.1 - 0.017 15.1 0.0 0.036 14.1 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone WD40 PF00400.27 XP_011273760.1 - 9.3e-74 240.9 16.7 2.9e-09 36.4 0.7 11.2 12 0 0 12 12 12 10 WD domain, G-beta repeat Utp12 PF04003.7 XP_011273760.1 - 7.4e-21 74.1 0.4 1.5e-20 73.1 0.3 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 XP_011273760.1 - 3.7e-06 25.3 3.5 0.022 12.9 0.1 4.9 5 2 0 6 6 6 3 Nucleoporin Nup120/160 AIG2 PF06094.7 XP_011273761.1 - 5.3e-13 49.3 0.1 6.3e-13 49.0 0.1 1.1 1 0 0 1 1 1 1 AIG2-like family HTH_45 PF14947.1 XP_011273761.1 - 0.0028 17.4 4.3 0.012 15.4 1.9 2.6 2 1 0 2 2 2 1 Winged helix-turn-helix PigN PF04987.9 XP_011273762.1 - 8.1e-130 433.4 46.5 1.1e-129 432.9 32.3 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 XP_011273762.1 - 1.3e-15 57.5 0.2 2.5e-12 46.8 0.1 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 XP_011273762.1 - 7.7e-10 38.4 0.1 1.2e-09 37.7 0.1 1.3 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 XP_011273762.1 - 0.00075 18.9 0.1 0.0024 17.3 0.0 1.8 2 0 0 2 2 2 1 Metalloenzyme superfamily Cytochrom_B562 PF07361.6 XP_011273762.1 - 0.25 11.7 2.2 0.58 10.5 1.5 1.6 1 0 0 1 1 1 0 Cytochrome b562 EF-hand_4 PF12763.2 XP_011273763.1 - 2.9e-21 75.1 0.1 2.6e-09 36.7 0.1 2.8 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 XP_011273763.1 - 0.0017 17.4 0.0 1 8.7 0.0 2.7 2 0 0 2 2 2 2 EF hand DUF1720 PF08226.6 XP_011273763.1 - 0.0038 17.2 33.1 0.0038 17.2 23.0 10.3 4 1 4 8 8 8 2 Domain of unknown function (DUF1720) EF-hand_7 PF13499.1 XP_011273763.1 - 0.0072 16.4 0.1 2.8 8.1 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain pair PQ-loop PF04193.9 XP_011273764.1 - 6.3e-21 73.6 8.6 1e-11 44.1 0.1 3.6 4 0 0 4 4 4 2 PQ loop repeat MtN3_slv PF03083.11 XP_011273764.1 - 0.075 12.9 10.5 0.08 12.8 1.0 2.6 3 0 0 3 3 3 0 Sugar efflux transporter for intercellular exchange DUF2523 PF10734.4 XP_011273764.1 - 9.9 6.4 11.6 2.8 8.2 0.3 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2523) CRAL_TRIO PF00650.15 XP_011273765.1 - 1.1e-24 86.7 0.1 1.6e-24 86.2 0.1 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 XP_011273765.1 - 6.3e-05 23.0 0.6 0.00045 20.3 0.0 2.5 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain Glyco_transf_8 PF01501.15 XP_011273766.1 - 5.5e-26 91.4 3.5 7.6e-26 90.9 2.4 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 XP_011273766.1 - 0.00085 18.7 0.0 0.0013 18.1 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Dehydratase_hem PF13816.1 XP_011273767.1 - 0.06 12.3 0.4 0.1 11.5 0.3 1.3 1 0 0 1 1 1 0 Haem-containing dehydratase TFIIE_beta PF02186.10 XP_011273768.1 - 8.3e-21 73.7 1.5 3.6e-20 71.7 1.0 2.1 2 0 0 2 2 2 1 TFIIE beta subunit core domain Cytidylate_kin2 PF13189.1 XP_011273770.1 - 0.043 13.7 0.0 0.081 12.8 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase-like family RNA_polI_A34 PF08208.6 XP_011273772.1 - 2.1e-36 125.5 31.4 2.6e-36 125.1 21.8 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 RR_TM4-6 PF06459.7 XP_011273772.1 - 0.49 10.2 13.9 0.61 9.9 9.7 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GAGA_bind PF06217.7 XP_011273772.1 - 0.78 9.6 14.0 0.97 9.3 9.7 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family DUF1510 PF07423.6 XP_011273772.1 - 2 7.7 24.6 3.3 7.0 17.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) LRR_8 PF13855.1 XP_011273773.1 - 0.014 15.1 5.3 0.15 11.8 0.5 3.2 3 0 0 3 3 3 0 Leucine rich repeat adh_short PF00106.20 XP_011273774.1 - 9e-08 32.2 0.0 1.2e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 XP_011273774.1 - 1.4e-06 27.9 0.1 1.9e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 XP_011273774.1 - 7.7e-05 22.5 0.1 9.7e-05 22.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 XP_011273774.1 - 0.00045 20.2 0.1 0.00067 19.7 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 XP_011273774.1 - 0.004 16.0 0.1 0.0062 15.4 0.1 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Enoyl_reductase PF12241.3 XP_011273774.1 - 0.031 13.2 0.1 0.045 12.7 0.0 1.2 1 0 0 1 1 1 0 Trans-2-enoyl-CoA reductase catalytic region G6PD_N PF00479.17 XP_011273774.1 - 0.056 13.6 0.0 0.099 12.8 0.0 1.4 1 0 0 1 1 1 0 Glucose-6-phosphate dehydrogenase, NAD binding domain LRR_8 PF13855.1 XP_011273776.1 - 0.017 14.8 10.0 0.21 11.3 1.8 4.6 4 1 1 5 5 5 0 Leucine rich repeat LRR_1 PF00560.28 XP_011273776.1 - 0.76 10.0 3.4 11 6.5 1.0 3.6 1 1 1 2 2 2 0 Leucine Rich Repeat Paf67 PF10255.4 XP_011273777.1 - 5.5e-128 427.2 5.3 7.3e-128 426.8 3.7 1.2 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.12 XP_011273777.1 - 0.021 14.7 0.0 0.087 12.7 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 XP_011273777.1 - 0.029 13.9 0.0 0.14 11.7 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 XP_011273777.1 - 0.036 14.0 0.0 0.14 12.0 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3896 PF13035.1 XP_011273777.1 - 0.27 11.3 3.7 5.9 7.0 1.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3896) DUF761 PF05553.6 XP_011273777.1 - 0.51 9.7 2.0 13 5.2 0.1 2.7 2 0 0 2 2 2 0 Cotton fibre expressed protein Arf PF00025.16 XP_011273778.1 - 3.1e-39 134.0 0.1 3.9e-39 133.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 XP_011273778.1 - 4e-11 42.5 0.0 5e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 XP_011273778.1 - 1.6e-10 41.5 0.0 2.3e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein G-alpha PF00503.15 XP_011273778.1 - 1.8e-09 36.8 0.1 2.5e-09 36.3 0.1 1.2 1 0 0 1 1 1 1 G-protein alpha subunit Gtr1_RagA PF04670.7 XP_011273778.1 - 2.5e-07 30.0 0.1 3e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 XP_011273778.1 - 4.9e-06 26.1 0.0 6e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 XP_011273778.1 - 1.6e-05 24.1 0.1 2.1e-05 23.8 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 XP_011273778.1 - 0.0068 16.3 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ste5_C PF12194.3 XP_011273780.1 - 1.2e-06 28.3 11.0 7.4e-05 22.4 7.6 2.9 1 1 0 1 1 1 1 Protein kinase Fus3-binding zf-RING_2 PF13639.1 XP_011273780.1 - 0.0085 15.8 6.3 0.016 15.0 4.3 1.4 1 0 0 1 1 1 1 Ring finger domain PH_4 PF15404.1 XP_011273782.1 - 9.4e-63 211.0 1.1 2.6e-61 206.3 0.0 3.2 3 0 0 3 3 3 1 Pleckstrin homology domain Spo7_2_N PF15407.1 XP_011273782.1 - 8.7e-18 63.5 0.1 3.5e-17 61.6 0.1 2.2 1 0 0 1 1 1 1 Sporulation protein family 7 PH PF00169.24 XP_011273782.1 - 3.4e-06 27.1 0.5 0.37 11.0 0.0 4.5 3 2 1 4 4 4 2 PH domain PH_6 PF15406.1 XP_011273782.1 - 0.0029 17.6 0.0 0.85 9.6 0.0 2.9 2 0 0 2 2 2 2 Pleckstrin homology domain COPI_assoc PF08507.5 XP_011273783.1 - 1.7e-14 53.6 0.0 2e-14 53.4 0.0 1.0 1 0 0 1 1 1 1 COPI associated protein 14-3-3 PF00244.15 XP_011273784.1 - 6.8e-115 382.1 4.2 7.9e-115 381.8 2.9 1.0 1 0 0 1 1 1 1 14-3-3 protein Peptidase_M24 PF00557.19 XP_011273785.1 - 8.5e-08 32.0 0.0 2.3e-07 30.6 0.0 1.7 2 0 0 2 2 2 1 Metallopeptidase family M24 AAA PF00004.24 XP_011273786.1 - 7.7e-41 139.3 0.0 2.2e-40 137.8 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 XP_011273786.1 - 1.5e-05 24.9 0.0 3.9e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 XP_011273786.1 - 2.7e-05 23.3 0.0 4.9e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 XP_011273786.1 - 3.3e-05 24.0 0.1 0.00082 19.5 0.1 2.7 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 XP_011273786.1 - 0.00032 20.6 0.1 0.0015 18.4 0.0 2.4 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.9 XP_011273786.1 - 0.00054 19.7 0.2 0.0043 16.7 0.0 2.7 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 XP_011273786.1 - 0.0021 16.8 0.0 0.0041 15.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 XP_011273786.1 - 0.003 17.4 0.1 0.015 15.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 XP_011273786.1 - 0.0036 16.7 0.1 0.17 11.2 0.1 2.4 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.16 XP_011273786.1 - 0.0047 16.1 0.1 0.0091 15.1 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 XP_011273786.1 - 0.0053 17.0 0.8 0.1 12.9 0.0 3.3 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.1 XP_011273786.1 - 0.0089 16.0 0.3 0.21 11.5 0.1 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 XP_011273786.1 - 0.012 15.3 0.2 0.036 13.8 0.0 1.8 2 0 0 2 2 1 0 Part of AAA domain RNA_helicase PF00910.17 XP_011273786.1 - 0.012 15.7 0.6 0.38 10.9 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.1 XP_011273786.1 - 0.013 15.0 0.1 0.047 13.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 XP_011273786.1 - 0.022 15.5 0.0 0.083 13.7 0.0 2.1 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 XP_011273786.1 - 0.034 13.5 0.0 0.079 12.3 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.21 XP_011273786.1 - 0.035 13.5 0.0 0.44 10.0 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain Vps4_C PF09336.5 XP_011273786.1 - 0.058 13.2 2.3 0.066 13.1 0.0 2.4 3 0 0 3 3 1 0 Vps4 C terminal oligomerisation domain NACHT PF05729.7 XP_011273786.1 - 0.064 12.9 0.7 2.1 8.0 0.0 3.0 2 1 1 3 3 3 0 NACHT domain EST1 PF10374.4 XP_011273786.1 - 2.2 8.2 7.1 1.1 9.2 1.8 2.6 1 1 1 2 2 2 0 Telomerase activating protein Est1 NIF PF03031.13 XP_011273787.1 - 2.2e-41 141.1 0.6 4.5e-41 140.1 0.4 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ESSS PF10183.4 XP_011273787.1 - 0.081 13.3 0.0 0.22 11.9 0.0 1.8 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) E1_dh PF00676.15 XP_011273788.1 - 7.2e-119 395.9 0.0 8.5e-119 395.7 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 XP_011273788.1 - 0.0088 15.0 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase AAA_12 PF13087.1 XP_011273789.1 - 2.2e-59 200.1 0.3 5.2e-59 198.9 0.2 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 XP_011273789.1 - 1.7e-43 148.8 1.4 1.7e-43 148.8 1.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 XP_011273789.1 - 5.3e-12 45.3 0.0 1.2e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 XP_011273789.1 - 8e-10 38.6 0.0 6.6e-09 35.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 XP_011273789.1 - 5.3e-07 29.6 0.4 5.3e-07 29.6 0.3 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 XP_011273789.1 - 2.9e-05 23.7 0.0 0.56 9.6 0.0 3.7 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DEAD PF00270.24 XP_011273789.1 - 0.0004 19.9 1.0 0.0031 17.0 0.5 2.6 2 1 0 2 2 2 1 DEAD/DEAH box helicase UvrD_C_2 PF13538.1 XP_011273789.1 - 0.00058 19.9 0.0 0.0019 18.3 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain PhoH PF02562.11 XP_011273789.1 - 0.0011 18.2 0.2 0.0041 16.3 0.2 1.9 1 1 0 1 1 1 1 PhoH-like protein AAA PF00004.24 XP_011273789.1 - 0.0035 17.5 0.0 0.049 13.8 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 XP_011273789.1 - 0.0075 15.9 0.4 0.025 14.2 0.3 1.9 1 0 0 1 1 1 1 Archaeal ATPase T2SE PF00437.15 XP_011273789.1 - 0.053 12.4 0.0 0.097 11.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.1 XP_011273789.1 - 0.099 12.6 0.0 0.29 11.0 0.0 1.8 2 0 0 2 2 1 0 AAA ATPase domain AAA_25 PF13481.1 XP_011273789.1 - 0.23 10.8 0.0 0.43 9.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain F-box-like PF12937.2 XP_011273791.1 - 0.00094 18.8 0.0 0.0031 17.2 0.0 1.9 1 0 0 1 1 1 1 F-box-like VHS PF00790.14 XP_011273792.1 - 9.9e-37 125.7 0.1 2.6e-36 124.3 0.1 1.7 1 0 0 1 1 1 1 VHS domain FYVE PF01363.16 XP_011273792.1 - 3.2e-18 65.3 3.7 6.9e-18 64.3 2.6 1.6 1 0 0 1 1 1 1 FYVE zinc finger Med26 PF08711.6 XP_011273792.1 - 0.091 12.2 0.1 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 TFIIS helical bundle-like domain zf-AN1 PF01428.11 XP_011273792.1 - 0.19 11.6 8.0 0.4 10.6 5.6 1.5 1 0 0 1 1 1 0 AN1-like Zinc finger RNA_pol_Rpo13 PF12136.3 XP_011273792.1 - 3.5 7.4 9.7 1.9 8.2 2.8 2.4 2 0 0 2 2 2 0 RNA polymerase Rpo13 subunit HTH domain SH3_1 PF00018.23 XP_011273793.1 - 5.9e-15 54.3 0.1 1.2e-14 53.3 0.1 1.6 1 0 0 1 1 1 1 SH3 domain FCH PF00611.18 XP_011273793.1 - 1.3e-14 54.1 2.7 1.3e-14 54.1 1.9 2.8 4 0 0 4 4 4 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.1 XP_011273793.1 - 9.8e-14 50.6 0.0 1.9e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 XP_011273793.1 - 3.7e-11 42.3 0.0 7.2e-11 41.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain TF_AP-2 PF03299.9 XP_011273793.1 - 0.0035 16.9 1.7 0.0035 16.9 1.2 2.5 2 1 1 3 3 3 1 Transcription factor AP-2 VLPT PF07122.6 XP_011273793.1 - 0.052 13.2 2.2 2.5 7.8 0.0 2.8 2 0 0 2 2 2 0 Variable length PCR target protein (VLPT) Histone PF00125.19 XP_011273794.1 - 3.3e-28 97.5 0.5 4.5e-28 97.1 0.3 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 XP_011273794.1 - 0.00049 20.2 0.1 0.00069 19.7 0.1 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 XP_011273794.1 - 0.0078 16.2 0.4 0.023 14.7 0.3 1.8 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Actin PF00022.14 XP_011273795.1 - 3.7e-27 94.7 0.2 1.9e-26 92.4 0.1 2.1 1 1 0 1 1 1 1 Actin PilM_2 PF11104.3 XP_011273795.1 - 0.0023 16.8 0.9 0.011 14.6 0.0 2.2 2 1 0 3 3 3 1 Type IV pilus assembly protein PilM; FtsA PF14450.1 XP_011273795.1 - 0.015 15.1 0.2 0.029 14.2 0.1 1.5 1 0 0 1 1 1 0 Cell division protein FtsA DUF4137 PF13593.1 XP_011273796.1 - 5.2e-114 380.5 18.2 6e-114 380.3 12.6 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) DUF3139 PF11337.3 XP_011273796.1 - 4.9 7.5 6.2 2.7 8.3 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) DUF1772 PF08592.6 XP_011273796.1 - 7.2 6.3 9.1 2 8.1 0.3 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF1772) Peptidase_S24 PF00717.18 XP_011273797.1 - 2.5e-07 30.2 0.5 2.7e-06 26.9 0.4 2.1 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 XP_011273797.1 - 0.00018 21.0 0.0 0.0069 15.9 0.0 2.5 1 1 1 2 2 2 1 Signal peptidase, peptidase S26 NAC PF01849.13 XP_011273798.1 - 1.1e-18 66.5 0.3 4.5e-18 64.5 0.0 2.1 2 1 1 3 3 3 1 NAC domain UBA PF00627.26 XP_011273798.1 - 0.0028 17.4 0.1 0.0073 16.1 0.1 1.7 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.1 XP_011273798.1 - 0.073 12.6 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 UBA-like domain DUF2296 PF10058.4 XP_011273799.1 - 1.9e-20 72.3 0.1 3.3e-20 71.5 0.1 1.4 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) DUF2207 PF09972.4 XP_011273799.1 - 0.028 13.0 1.0 0.043 12.4 0.7 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Sld5 PF05916.6 XP_011273799.1 - 0.085 13.1 0.1 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 GINS complex protein DUF4446 PF14584.1 XP_011273799.1 - 0.1 12.4 3.3 0.76 9.5 1.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4446) TF_Zn_Ribbon PF08271.7 XP_011273799.1 - 0.12 11.6 3.0 0.62 9.4 2.1 2.1 1 1 0 1 1 1 0 TFIIB zinc-binding zf-ribbon_3 PF13248.1 XP_011273799.1 - 0.16 11.2 2.2 5.6 6.2 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-Mss51 PF13824.1 XP_011273799.1 - 4.6 7.1 6.1 0.87 9.4 0.9 2.1 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Ctf8 PF09696.5 XP_011273800.1 - 4.9e-27 94.1 0.1 6.7e-27 93.6 0.1 1.2 1 0 0 1 1 1 1 Ctf8 Glyco_hydro_47 PF01532.15 XP_011273801.1 - 9.5e-168 558.5 0.1 1.2e-167 558.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Cys_Met_Meta_PP PF01053.15 XP_011273802.1 - 1.6e-33 115.5 0.0 2.2e-33 115.0 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 XP_011273802.1 - 0.0021 17.1 0.0 0.0034 16.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Allantoicase PF03561.10 XP_011273803.1 - 3.5e-101 334.9 0.4 4.6e-54 182.0 0.0 2.0 2 0 0 2 2 2 2 Allantoicase repeat F5_F8_type_C PF00754.20 XP_011273803.1 - 0.00023 20.9 1.7 0.00036 20.3 0.0 2.0 2 1 0 2 2 2 1 F5/8 type C domain DUF4649 PF15507.1 XP_011273806.1 - 0.051 13.3 1.2 4 7.2 0.2 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4649) CLTH PF10607.4 XP_011273807.1 - 1.8e-32 111.9 6.4 1.8e-32 111.9 4.4 2.4 2 1 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain U-box PF04564.10 XP_011273807.1 - 0.00094 19.1 0.0 0.0036 17.2 0.0 2.0 1 0 0 1 1 1 1 U-box domain Fe-S_assembly PF04384.8 XP_011273807.1 - 0.0042 17.4 0.3 0.016 15.5 0.2 2.0 1 0 0 1 1 1 1 Iron-sulphur cluster assembly YvfG PF09628.5 XP_011273807.1 - 0.028 14.5 2.8 17 5.6 0.0 3.9 3 1 0 3 3 3 0 YvfG protein DUF3269 PF11673.3 XP_011273807.1 - 0.16 12.4 1.6 7.9 6.9 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3269) RRM_1 PF00076.17 XP_011273808.1 - 0.015 14.9 0.1 0.051 13.1 0.0 2.0 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 XP_011273808.1 - 0.041 13.7 0.0 0.083 12.7 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 XP_011273808.1 - 0.043 13.8 0.0 0.13 12.2 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 XP_011273808.1 - 0.056 13.2 2.1 0.2 11.5 0.0 2.6 3 0 0 3 3 3 0 RNA binding motif DUF2854 PF11016.3 XP_011273808.1 - 0.068 12.6 0.0 0.17 11.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2854) zf-RING_2 PF13639.1 XP_011273809.1 - 3.5e-11 42.7 6.3 5.2e-11 42.1 4.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 XP_011273809.1 - 5.6e-08 32.7 5.2 1.5e-07 31.4 3.6 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 XP_011273809.1 - 0.00021 21.2 5.9 0.00033 20.6 4.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 XP_011273809.1 - 0.00027 20.5 2.2 0.00043 19.8 1.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 XP_011273809.1 - 0.0011 18.7 3.7 0.0024 17.6 2.6 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 XP_011273809.1 - 0.0048 16.5 5.2 0.0089 15.6 3.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 XP_011273809.1 - 0.0078 16.2 2.9 0.014 15.4 2.0 1.4 1 0 0 1 1 1 1 RING-variant domain DUF983 PF06170.7 XP_011273809.1 - 0.044 13.9 0.5 0.87 9.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF983) FANCL_C PF11793.3 XP_011273809.1 - 0.046 13.6 3.1 0.41 10.6 2.2 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_5 PF14634.1 XP_011273809.1 - 0.048 13.3 3.9 0.083 12.6 2.7 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_3 PF14369.1 XP_011273809.1 - 0.078 12.9 0.5 5.4 7.1 0.0 2.4 2 0 0 2 2 2 0 zinc-finger zf-RING_4 PF14570.1 XP_011273809.1 - 0.1 12.1 2.9 0.26 10.8 2.0 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Rad50_zn_hook PF04423.9 XP_011273809.1 - 0.41 10.1 3.0 1.8 8.1 0.3 2.8 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-P11 PF03854.9 XP_011273809.1 - 1.2 8.6 5.4 0.61 9.5 1.3 2.0 2 0 0 2 2 2 0 P-11 zinc finger Ribosomal_S10 PF00338.17 XP_011273810.1 - 6.4e-23 80.4 0.0 1.4e-22 79.3 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e FtsJ PF01728.14 XP_011273811.1 - 6.8e-65 218.4 0.0 8.5e-65 218.1 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 XP_011273811.1 - 0.021 15.3 0.0 0.047 14.2 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Nol1_Nop2_Fmu PF01189.12 XP_011273811.1 - 0.14 11.5 0.0 0.71 9.2 0.0 2.0 3 0 0 3 3 3 0 NOL1/NOP2/sun family MFS_1 PF07690.11 XP_011273812.1 - 1.7e-38 132.2 40.3 1.7e-38 132.2 27.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 XP_011273812.1 - 2.1e-11 43.0 36.1 5.1e-11 41.8 25.0 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 XP_011273812.1 - 1.7e-05 23.2 0.8 1.7e-05 23.2 0.6 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Cytochrome-c551 PF10643.4 XP_011273812.1 - 0.074 12.3 0.7 0.14 11.4 0.5 1.4 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 TIM PF00121.13 XP_011273813.1 - 1.3e-89 299.5 0.1 1.4e-89 299.3 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase Vinculin PF01044.14 XP_011273813.1 - 0.03 12.3 0.0 0.038 12.0 0.0 1.1 1 0 0 1 1 1 0 Vinculin family His_Phos_1 PF00300.17 XP_011273814.1 - 1e-34 119.9 0.7 2e-34 118.9 0.0 1.7 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Peptidase_S49_N PF08496.5 XP_011273815.1 - 1.7 8.4 16.7 0.3 10.8 1.6 2.5 2 0 0 2 2 2 0 Peptidase family S49 N-terminal JAB PF01398.16 XP_011273816.1 - 1.4e-05 24.8 0.0 3e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF4298 PF14131.1 XP_011273816.1 - 0.086 12.7 2.6 0.25 11.2 1.8 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4298) tRNA-synt_2 PF00152.15 XP_011273817.1 - 5.4e-89 298.2 0.2 8.3e-89 297.6 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 XP_011273817.1 - 1.5e-12 47.2 0.1 3.1e-12 46.1 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 XP_011273817.1 - 1.1e-07 31.3 0.1 0.00092 18.4 0.1 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Peptidase_S46 PF10459.4 XP_011273817.1 - 0.11 10.9 0.6 3.8 5.8 0.0 2.1 2 0 0 2 2 2 0 Peptidase S46 NARP1 PF12569.3 XP_011273817.1 - 1.6 7.3 6.4 2.8 6.5 4.4 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF964 PF06133.6 XP_011273819.1 - 0.059 13.3 4.0 0.12 12.4 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF964) zf-H2C2_2 PF13465.1 XP_011273820.1 - 2e-05 24.6 17.9 0.0001 22.4 2.0 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 XP_011273820.1 - 2.4e-05 24.3 16.5 5e-05 23.3 2.3 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 XP_011273820.1 - 0.00014 21.9 14.7 0.06 13.7 3.4 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 XP_011273820.1 - 0.27 11.4 6.1 0.31 11.2 0.8 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type IBR PF01485.16 XP_011273820.1 - 1.4 8.8 7.4 1.8 8.4 0.8 2.4 1 1 1 2 2 2 0 IBR domain LRR_8 PF13855.1 XP_011273822.1 - 0.74 9.6 9.1 0.42 10.3 2.1 3.4 3 1 0 3 3 3 0 Leucine rich repeat MFS_1 PF07690.11 XP_011273824.1 - 3.2e-32 111.6 30.3 3.2e-32 111.6 21.0 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 XP_011273824.1 - 2.9e-06 26.1 31.1 6.3e-06 25.0 21.5 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.2 XP_011273824.1 - 0.011 15.4 3.1 0.063 13.0 0.0 3.0 3 0 0 3 3 3 0 MFS_1 like family MFS_1 PF07690.11 XP_011273825.1 - 5.3e-33 114.1 29.2 5.3e-33 114.1 20.3 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 XP_011273825.1 - 2.3e-06 26.4 31.0 7.4e-06 24.7 21.5 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.2 XP_011273825.1 - 0.0063 16.2 4.1 0.012 15.4 0.0 3.0 3 0 0 3 3 3 1 MFS_1 like family DUF2274 PF10038.4 XP_011273826.1 - 0.037 14.1 0.0 0.57 10.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2274) LRR_4 PF12799.2 XP_011273827.1 - 0.13 11.8 5.0 2.9 7.6 2.0 3.2 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) DUF3317 PF11779.3 XP_011273828.1 - 9.3e-05 21.7 6.1 0.00013 21.3 4.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) Pkinase PF00069.20 XP_011273829.1 - 1.7e-38 132.2 0.1 1.7e-38 132.2 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011273829.1 - 1.9e-27 95.9 0.0 1.9e-27 95.9 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 XP_011273829.1 - 5.5e-07 28.8 0.0 5.5e-07 28.8 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 XP_011273829.1 - 1.4e-06 27.4 0.0 3.3e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 XP_011273829.1 - 0.014 15.0 0.0 2.2 7.9 0.1 2.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family ORC2 PF04084.9 XP_011273830.1 - 4.5e-103 344.5 6.0 7.3e-103 343.8 4.2 1.3 1 0 0 1 1 1 1 Origin recognition complex subunit 2 AT_hook PF02178.14 XP_011273830.1 - 0.0051 16.3 59.9 0.21 11.3 1.0 7.9 7 0 0 7 7 7 6 AT hook motif TFIIS_C PF01096.13 XP_011273831.1 - 5.4e-22 77.1 1.3 5.4e-22 77.1 0.9 2.8 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 XP_011273831.1 - 1.8e-10 40.2 0.3 1.8e-10 40.2 0.2 2.4 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit PhnA_Zn_Ribbon PF08274.7 XP_011273831.1 - 0.00038 20.1 6.5 0.21 11.3 0.1 3.2 3 0 0 3 3 3 2 PhnA Zinc-Ribbon DUF2387 PF09526.5 XP_011273831.1 - 0.0034 17.2 2.4 0.79 9.6 0.2 2.4 2 0 0 2 2 2 2 Probable metal-binding protein (DUF2387) DZR PF12773.2 XP_011273831.1 - 0.018 14.8 5.1 0.45 10.3 0.1 2.5 2 1 0 2 2 2 0 Double zinc ribbon Zn_Tnp_IS1595 PF12760.2 XP_011273831.1 - 0.02 14.6 6.2 0.12 12.2 0.1 2.8 2 2 0 2 2 2 0 Transposase zinc-ribbon domain zinc_ribbon_5 PF13719.1 XP_011273831.1 - 0.025 14.1 9.2 0.3 10.7 0.2 3.3 3 1 1 4 4 4 0 zinc-ribbon domain Elf1 PF05129.8 XP_011273831.1 - 0.04 13.6 1.5 6 6.6 0.2 2.2 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Baculo_LEF5_C PF11792.3 XP_011273831.1 - 0.084 12.2 0.4 0.084 12.2 0.3 1.8 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain zinc_ribbon_4 PF13717.1 XP_011273831.1 - 0.28 10.9 11.7 0.35 10.6 0.3 3.6 3 1 1 4 4 4 0 zinc-ribbon domain UPF0547 PF10571.4 XP_011273831.1 - 0.29 10.8 9.9 6 6.6 0.0 3.8 5 0 0 5 5 5 0 Uncharacterised protein family UPF0547 IBR PF01485.16 XP_011273831.1 - 0.6 10.0 8.6 0.88 9.4 0.2 2.8 2 1 0 2 2 2 0 IBR domain TF_Zn_Ribbon PF08271.7 XP_011273831.1 - 0.97 8.8 6.3 8.7 5.7 0.3 3.1 3 1 0 3 3 3 0 TFIIB zinc-binding zf-RING_2 PF13639.1 XP_011273831.1 - 1.8 8.4 5.5 3 7.7 1.1 2.7 3 0 0 3 3 3 0 Ring finger domain zf-C3HC4_2 PF13923.1 XP_011273831.1 - 6.1 6.9 6.7 6.6 6.8 0.8 2.8 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) RRN7 PF11781.3 XP_011273831.1 - 9.7 5.7 6.9 21 4.7 0.2 3.6 4 0 0 4 4 4 0 RNA polymerase I-specific transcription initiation factor Rrn7 Lactamase_B_2 PF12706.2 XP_011273832.1 - 4.9e-12 45.7 0.0 9.3e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 XP_011273832.1 - 0.00022 20.9 0.1 0.00072 19.2 0.1 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily DRMBL PF07522.9 XP_011273832.1 - 0.0099 15.9 0.3 0.026 14.5 0.2 1.7 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase PDEase_II PF02112.10 XP_011273832.1 - 0.055 12.3 0.2 1.6 7.6 0.2 2.2 1 1 1 2 2 2 0 cAMP phosphodiesterases class-II Coprogen_oxidas PF01218.13 XP_011273833.1 - 4e-134 445.7 0.0 4.6e-134 445.6 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase FA_desaturase PF00487.19 XP_011273834.1 - 1.2e-25 90.4 14.3 1.6e-25 90.0 9.9 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 XP_011273834.1 - 4.6e-19 67.3 0.1 7.7e-19 66.6 0.1 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) MFS_1 PF07690.11 XP_011273835.1 - 4.5e-30 104.5 15.0 4.5e-30 104.5 10.4 1.8 1 1 0 2 2 2 1 Major Facilitator Superfamily DUF308 PF03729.8 XP_011273835.1 - 0.46 10.5 0.0 0.46 10.5 0.0 5.5 6 0 0 6 6 6 0 Short repeat of unknown function (DUF308) DUF2157 PF09925.4 XP_011273835.1 - 0.78 9.3 11.7 0.69 9.5 0.1 3.1 3 0 0 3 3 3 0 Predicted membrane protein (DUF2157) DUF4131 PF13567.1 XP_011273835.1 - 2.8 7.3 13.9 6.4 6.1 0.0 3.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4131) FMO-like PF00743.14 XP_011273836.1 - 4.8e-37 127.3 0.0 4.9e-16 58.0 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 XP_011273836.1 - 2.4e-10 40.8 0.0 3.9e-09 36.8 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 XP_011273836.1 - 1e-07 32.0 0.0 9.8e-05 22.3 0.1 3.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 XP_011273836.1 - 2.3e-07 30.0 1.2 0.00034 19.6 0.1 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 XP_011273836.1 - 1e-06 28.6 0.1 5.8e-06 26.1 0.0 2.4 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 XP_011273836.1 - 2.6e-05 24.1 0.0 6.5e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Mrr_cat_2 PF13156.1 XP_011273836.1 - 0.016 15.1 0.2 0.031 14.1 0.1 1.5 1 0 0 1 1 1 0 Restriction endonuclease Het-C PF07217.6 XP_011273836.1 - 0.019 13.1 0.1 0.031 12.4 0.1 1.2 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C Semialdhyde_dh PF01118.19 XP_011273836.1 - 0.086 13.1 0.0 12 6.1 0.0 2.5 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Thi4 PF01946.12 XP_011273836.1 - 0.09 11.8 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Thi4 family MFS_1 PF07690.11 XP_011273837.1 - 1.6e-20 73.1 34.4 2.4e-20 72.5 23.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Esterase PF00756.15 XP_011273838.1 - 2.4e-53 181.1 0.1 3e-53 180.8 0.1 1.0 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 XP_011273838.1 - 2.5e-06 27.3 0.0 3.6e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 XP_011273838.1 - 0.00088 18.5 0.1 0.0013 17.9 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.2 XP_011273838.1 - 0.0025 16.7 0.0 0.0055 15.6 0.0 1.5 1 1 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_2 PF02230.11 XP_011273838.1 - 0.0037 16.7 0.0 0.0062 15.9 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 XP_011273838.1 - 0.0061 16.4 0.0 0.009 15.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 XP_011273838.1 - 0.0074 15.9 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.20 XP_011273838.1 - 0.011 15.3 0.0 0.02 14.4 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Peptidase_S15 PF02129.13 XP_011273838.1 - 0.029 13.7 0.9 0.44 9.9 0.6 2.1 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Chlorophyllase PF07224.6 XP_011273838.1 - 0.1 11.3 0.0 0.64 8.7 0.0 1.9 2 0 0 2 2 2 0 Chlorophyllase RCC1_2 PF13540.1 XP_011273839.1 - 5.4e-18 64.0 22.0 8.2e-10 38.0 0.6 6.0 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 XP_011273839.1 - 2.3e-15 56.5 7.1 8.7e-05 22.6 0.0 6.7 7 0 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat Tachylectin PF14517.1 XP_011273839.1 - 0.0051 16.1 0.8 0.019 14.2 0.3 2.0 2 0 0 2 2 2 1 Tachylectin F-box-like PF12937.2 XP_011273839.1 - 0.084 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 F-box-like Peptidase_M20 PF01546.23 XP_011273840.1 - 4.2e-26 91.6 0.0 6.9e-26 90.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.27 XP_011273840.1 - 1.4e-20 72.2 7.0 2.4e-08 33.5 0.0 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat M20_dimer PF07687.9 XP_011273840.1 - 3.6e-12 46.0 0.0 1.3e-11 44.2 0.0 2.0 2 0 0 2 2 2 1 Peptidase dimerisation domain Nup160 PF11715.3 XP_011273840.1 - 0.0022 16.2 0.8 0.29 9.2 0.0 2.9 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Hira PF07569.6 XP_011273840.1 - 0.0023 17.1 0.2 1.2 8.2 0.0 2.5 2 0 0 2 2 2 2 TUP1-like enhancer of split PQQ_3 PF13570.1 XP_011273840.1 - 0.041 14.1 0.1 9.4 6.6 0.0 4.3 5 0 0 5 5 5 0 PQQ-like domain Phos_pyr_kin PF08543.7 XP_011273841.1 - 1.3e-12 47.4 0.0 1.7e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 XP_011273841.1 - 3.4e-09 36.2 0.0 1.7e-08 33.9 0.0 1.9 2 0 0 2 2 2 1 pfkB family carbohydrate kinase DUF520 PF04461.8 XP_011273841.1 - 0.073 12.9 0.3 0.54 10.0 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF520) Thi4 PF01946.12 XP_011273842.1 - 1.1e-93 312.5 0.3 1.3e-93 312.3 0.2 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 XP_011273842.1 - 1.3e-08 34.1 0.8 7.2e-08 31.7 0.2 1.9 1 1 1 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 XP_011273842.1 - 7e-07 28.4 0.7 3e-05 23.0 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 XP_011273842.1 - 1e-06 28.6 0.1 6.3e-06 26.1 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 XP_011273842.1 - 2.5e-06 27.5 0.3 4.5e-06 26.6 0.2 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 XP_011273842.1 - 4.8e-06 26.4 0.1 3.3e-05 23.7 0.1 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 XP_011273842.1 - 1.1e-05 24.5 0.1 1.8e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 XP_011273842.1 - 0.00015 21.8 0.2 0.00034 20.7 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 XP_011273842.1 - 0.0005 19.2 0.1 0.00078 18.6 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 XP_011273842.1 - 0.00053 18.5 0.3 0.00082 17.9 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 XP_011273842.1 - 0.00054 18.9 0.1 0.0018 17.1 0.0 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A Trp_halogenase PF04820.9 XP_011273842.1 - 0.018 13.6 0.2 0.026 13.1 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase PI3_PI4_kinase PF00454.22 XP_011273843.1 - 1.5e-48 165.3 0.0 2.3e-48 164.7 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF320 PF03777.8 XP_011273843.1 - 1 9.1 3.6 1.3 8.8 0.5 2.3 2 0 0 2 2 2 0 Small secreted domain (DUF320) MFS_1 PF07690.11 XP_011273844.1 - 2.5e-36 125.1 17.2 2.5e-36 125.1 11.9 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 XP_011273844.1 - 0.022 14.5 5.5 0.025 14.3 2.5 2.1 2 0 0 2 2 2 0 MFS_1 like family NAD_binding_5 PF07994.7 XP_011273845.1 - 2.3e-109 365.4 0.3 2.8e-109 365.1 0.2 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 XP_011273845.1 - 3.6e-42 142.7 1.0 1.2e-41 141.0 0.7 2.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase HTH_19 PF12844.2 XP_011273845.1 - 0.0046 16.9 0.7 2.3 8.3 0.0 3.6 4 0 0 4 4 4 2 Helix-turn-helix domain ADH_N PF08240.7 XP_011273846.1 - 1.9e-20 72.6 4.3 3.5e-20 71.7 3.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 XP_011273846.1 - 1.2e-11 44.2 0.0 1.9e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 XP_011273846.1 - 0.00015 20.9 0.1 0.00035 19.7 0.1 1.5 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 XP_011273846.1 - 0.0042 16.9 0.0 0.0058 16.4 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.16 XP_011273846.1 - 0.014 14.9 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain CAF1 PF04857.15 XP_011273847.1 - 2.1e-53 181.3 8.8 2.1e-53 181.3 6.1 2.1 2 0 0 2 2 2 1 CAF1 family ribonuclease PAT1 PF09770.4 XP_011273847.1 - 1.3 7.1 43.1 1.8 6.7 29.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4407 PF14362.1 XP_011273847.1 - 8.2 5.2 17.2 12 4.7 11.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NTF2 PF02136.15 XP_011273848.1 - 2.7e-21 76.1 0.6 7.2e-21 74.7 0.2 2.0 2 0 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain Nup35_RRM_2 PF14605.1 XP_011273848.1 - 0.0024 17.5 0.0 0.0044 16.7 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif UBA_3 PF09288.5 XP_011273849.1 - 1.9e-21 75.3 1.9 2e-21 75.3 0.3 1.8 2 0 0 2 2 2 1 Fungal ubiquitin-associated domain UQ_con PF00179.21 XP_011273849.1 - 7e-19 67.6 0.0 4.4e-09 35.9 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme CDC50 PF03381.10 XP_011273850.1 - 2.2e-99 332.1 0.1 2.7e-99 331.8 0.1 1.0 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Not1 PF04054.10 XP_011273851.1 - 5.1e-139 463.3 6.1 5.1e-139 463.3 4.2 3.2 3 0 0 3 3 3 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 XP_011273851.1 - 1e-43 148.5 0.9 1e-43 148.5 0.6 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) Y_phosphatase2 PF03162.8 XP_011273852.1 - 9.1e-33 112.9 2.2 1.8e-32 112.0 1.5 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family MFS_1 PF07690.11 XP_011273853.1 - 2.7e-33 115.1 37.5 2.1e-30 105.6 27.8 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 XP_011273853.1 - 4.8e-14 51.8 6.3 4.8e-14 51.8 4.3 3.2 3 1 0 3 3 3 1 Sugar (and other) transporter Fungal_trans PF04082.13 XP_011273854.1 - 8.4e-12 44.5 1.7 3.9e-11 42.3 1.2 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 XP_011273854.1 - 4.8e-08 32.7 11.5 8.9e-08 31.9 8.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LicD PF04991.8 XP_011273855.1 - 6.6e-13 49.2 0.0 6.6e-13 49.2 0.0 3.3 4 0 0 4 4 4 1 LicD family Indigoidine_A PF04227.7 XP_011273856.1 - 2e-123 411.3 0.1 2.9e-123 410.7 0.1 1.3 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.19 XP_011273856.1 - 3.4e-15 55.9 0.7 2.7e-09 36.5 0.0 2.6 2 1 0 2 2 2 2 pfkB family carbohydrate kinase HSP9_HSP12 PF04119.7 XP_011273857.1 - 8.6e-25 86.6 5.2 9.5e-25 86.4 3.6 1.0 1 0 0 1 1 1 1 Heat shock protein 9/12 DUF4363 PF14276.1 XP_011273857.1 - 0.051 13.2 0.1 0.065 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) ApoA-II PF04711.8 XP_011273857.1 - 0.11 12.3 0.8 0.14 12.0 0.5 1.3 1 1 0 1 1 1 0 Apolipoprotein A-II (ApoA-II) Sugar_tr PF00083.19 XP_011273858.1 - 3.5e-73 246.7 26.8 4.3e-73 246.4 18.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 XP_011273858.1 - 2.2e-26 92.3 29.7 2.2e-26 92.3 20.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily OPT PF03169.10 XP_011273859.1 - 8.2e-177 589.3 47.8 9.4e-177 589.1 33.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF2951 PF11166.3 XP_011273859.1 - 0.23 11.3 0.0 0.47 10.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) DAO PF01266.19 XP_011273860.1 - 4e-51 174.0 0.0 4.6e-51 173.7 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 XP_011273860.1 - 2.9e-05 24.0 0.4 0.0038 17.1 0.1 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 XP_011273860.1 - 0.00063 18.4 0.0 0.0012 17.6 0.0 1.4 1 0 0 1 1 1 1 Tryptophan halogenase NAD_binding_8 PF13450.1 XP_011273860.1 - 0.0013 18.6 0.0 0.0024 17.8 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 XP_011273860.1 - 0.0016 18.8 0.0 0.0043 17.4 0.0 1.8 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 XP_011273860.1 - 0.0019 18.2 0.0 0.015 15.4 0.0 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 XP_011273860.1 - 0.0082 14.6 0.1 1.4 7.3 0.0 2.3 2 0 0 2 2 2 2 HI0933-like protein GIDA PF01134.17 XP_011273860.1 - 0.0092 14.8 0.0 0.34 9.7 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_7 PF13241.1 XP_011273860.1 - 0.012 15.8 0.0 0.032 14.4 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding TrkA_N PF02254.13 XP_011273860.1 - 0.02 14.8 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain FAD_binding_3 PF01494.14 XP_011273860.1 - 0.033 13.2 0.0 0.059 12.4 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain GalKase_gal_bdg PF10509.4 XP_011273860.1 - 0.036 13.3 0.0 0.089 12.0 0.0 1.6 1 0 0 1 1 1 0 Galactokinase galactose-binding signature SIS PF01380.17 XP_011273860.1 - 0.15 11.6 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 SIS domain Fungal_trans_2 PF11951.3 XP_011273861.1 - 3.3e-45 154.3 4.9 4.7e-45 153.8 3.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 XP_011273861.1 - 1.1e-06 28.4 11.3 3.1e-06 27.0 7.8 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1729 PF08354.5 XP_011273862.1 - 2.3e-15 56.0 0.2 4.5e-15 55.1 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) TauD PF02668.11 XP_011273863.1 - 3.2e-37 128.5 0.0 3.9e-37 128.3 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family P5-ATPase PF12409.3 XP_011273864.1 - 4.8e-35 119.9 0.1 4.8e-35 119.9 0.0 2.5 3 0 0 3 3 3 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.15 XP_011273864.1 - 3.1e-28 98.3 0.0 6.7e-28 97.2 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 XP_011273864.1 - 5.5e-26 91.9 0.0 1e-25 91.0 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 XP_011273864.1 - 2.2e-17 64.2 0.0 1.1e-16 61.8 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 XP_011273864.1 - 2.5e-05 24.1 0.0 5.7e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 XP_011273864.1 - 0.026 13.9 0.0 0.061 12.7 0.0 1.6 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 XP_011273864.1 - 0.039 13.5 0.0 0.63 9.5 0.0 2.7 4 0 0 4 4 4 0 haloacid dehalogenase-like hydrolase RVT_1 PF00078.22 XP_011273865.1 - 2e-18 66.5 1.3 2.2e-16 59.8 0.9 2.5 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 XP_011273865.1 - 5e-17 62.1 0.0 3.1e-16 59.5 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.1 XP_011273865.1 - 0.0018 17.7 0.0 0.0053 16.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain DUF4451 PF14616.1 XP_011273866.1 - 3.4e-09 36.5 3.9 7.8e-09 35.3 2.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) Troponin-I_N PF11636.3 XP_011273867.1 - 0.0049 16.5 0.5 0.017 14.8 0.3 1.9 1 0 0 1 1 1 1 Troponin I residues 1-32 MAGE_N PF12440.3 XP_011273867.1 - 1.6 9.0 6.8 1.9 8.8 0.9 2.4 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal Methyltransf_31 PF13847.1 XP_011273868.1 - 1e-25 90.1 0.0 1.3e-25 89.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 XP_011273868.1 - 2.6e-24 85.5 0.0 4.6e-24 84.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 XP_011273868.1 - 1.9e-16 60.1 0.0 2.5e-16 59.7 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 XP_011273868.1 - 3.1e-15 56.4 0.0 7.1e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 XP_011273868.1 - 6.8e-15 55.6 0.0 1.1e-14 54.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 XP_011273868.1 - 1.1e-14 54.1 0.0 1.5e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 XP_011273868.1 - 4.9e-13 49.2 0.0 7.6e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 XP_011273868.1 - 2.7e-09 36.1 0.0 3.4e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PCMT PF01135.14 XP_011273868.1 - 1.1e-07 31.5 0.0 1.6e-07 31.0 0.0 1.3 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.12 XP_011273868.1 - 7.2e-07 28.4 0.0 4.4e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_26 PF13659.1 XP_011273868.1 - 9.6e-07 28.8 0.0 1.7e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 XP_011273868.1 - 4.3e-06 26.2 0.0 8.4e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW CheR PF01739.13 XP_011273868.1 - 7.9e-06 25.2 0.0 0.00016 21.0 0.0 2.1 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain MTS PF05175.9 XP_011273868.1 - 1e-05 25.0 0.0 1.8e-05 24.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_29 PF03141.11 XP_011273868.1 - 0.00018 19.9 0.0 0.00026 19.4 0.0 1.5 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_8 PF05148.10 XP_011273868.1 - 0.0014 18.3 0.0 0.0064 16.1 0.0 1.9 2 0 0 2 2 2 1 Hypothetical methyltransferase RrnaAD PF00398.15 XP_011273868.1 - 0.0056 15.7 0.0 0.011 14.8 0.0 1.4 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase V_cholerae_RfbT PF05575.6 XP_011273868.1 - 0.0071 15.4 0.0 0.01 14.9 0.0 1.3 1 0 0 1 1 1 1 Vibrio cholerae RfbT protein CMAS PF02353.15 XP_011273868.1 - 0.012 14.6 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.1 XP_011273868.1 - 0.013 15.1 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain NAS PF03059.11 XP_011273868.1 - 0.02 14.0 0.0 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 Nicotianamine synthase protein UPF0020 PF01170.13 XP_011273868.1 - 0.024 14.2 0.0 0.052 13.1 0.0 1.5 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 PrmA PF06325.8 XP_011273868.1 - 0.053 12.6 0.0 0.087 11.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DREV PF05219.7 XP_011273868.1 - 0.066 12.0 0.0 0.14 11.0 0.0 1.4 1 1 0 1 1 1 0 DREV methyltransferase FtsJ PF01728.14 XP_011273868.1 - 0.099 12.6 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase MFS_1 PF07690.11 XP_011273869.1 - 1.4e-34 119.3 15.0 1.4e-34 119.3 10.4 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily VIT1 PF01988.14 XP_011273869.1 - 0.21 11.0 2.3 0.19 11.2 0.4 1.6 1 1 0 1 1 1 0 VIT family DUF3792 PF12670.2 XP_011273869.1 - 8.2 6.3 10.6 1.1 9.0 0.4 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3792) HSP70 PF00012.15 XP_011273870.1 - 8e-77 258.5 4.1 1.2e-76 257.8 2.9 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 XP_011273870.1 - 2.9e-06 26.1 0.4 2.9e-06 26.1 0.3 1.7 2 0 0 2 2 2 1 MreB/Mbl protein AA_permease PF00324.16 XP_011273871.1 - 4.7e-134 447.3 42.9 5.7e-134 447.0 29.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 XP_011273871.1 - 2.7e-39 134.9 45.1 3.2e-39 134.6 31.3 1.0 1 0 0 1 1 1 1 Amino acid permease LRR_7 PF13504.1 XP_011273872.1 - 0.06 13.5 3.8 44 4.9 0.0 5.3 5 0 0 5 5 5 0 Leucine rich repeat NifU_N PF01592.11 XP_011273873.1 - 3.4e-53 178.9 0.0 3.9e-53 178.7 0.0 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain Peptidase_M24 PF00557.19 XP_011273874.1 - 7.6e-55 185.7 0.0 9.8e-55 185.3 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 XP_011273874.1 - 1.7e-23 82.4 0.0 3.4e-23 81.5 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Ribosomal_L18p PF00861.17 XP_011273875.1 - 1.9e-44 150.7 1.1 2.3e-44 150.4 0.0 1.7 2 0 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 XP_011273875.1 - 5.1e-32 110.3 6.4 5.1e-32 110.3 4.5 1.9 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Metal_resist PF13801.1 XP_011273875.1 - 0.022 14.7 0.0 0.045 13.7 0.0 1.5 1 0 0 1 1 1 0 Heavy-metal resistance DUF3626 PF12294.3 XP_011273875.1 - 0.05 12.6 0.1 0.084 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3626) OPT PF03169.10 XP_011273876.1 - 2e-143 479.1 44.3 2.3e-143 478.9 30.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4239 PF14023.1 XP_011273876.1 - 0.035 13.4 0.0 0.081 12.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) DUF1212 PF06738.7 XP_011273876.1 - 0.72 9.2 8.6 0.66 9.3 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1212) CtaG_Cox11 PF04442.9 XP_011273878.1 - 3.2e-55 186.0 0.0 4.5e-55 185.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Mu-like_gpT PF10124.4 XP_011273879.1 - 0.044 12.7 0.4 0.078 11.9 0.0 1.5 2 0 0 2 2 2 0 Mu-like prophage major head subunit gpT Acyl_transf_1 PF00698.16 XP_011273880.1 - 7.2e-09 35.4 0.0 8.9e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain Mito_carr PF00153.22 XP_011273881.1 - 4e-62 205.9 0.6 3.8e-19 68.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2407_C PF13373.1 XP_011273882.1 - 1e-41 142.0 1.1 6.9e-41 139.4 0.6 2.2 2 0 0 2 2 2 1 DUF2407 C-terminal domain DUF2407 PF10302.4 XP_011273882.1 - 1.4e-17 63.6 0.6 3.3e-17 62.4 0.2 1.7 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain DUF2453 PF10507.4 XP_011273882.1 - 0.015 15.1 0.0 0.047 13.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2453) ubiquitin PF00240.18 XP_011273882.1 - 0.045 13.1 0.0 0.12 11.8 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin family Acetyltransf_11 PF13720.1 XP_011273882.1 - 0.092 12.9 0.0 0.21 11.8 0.0 1.7 1 0 0 1 1 1 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 MTP18 PF10558.4 XP_011273883.1 - 1.9e-62 209.5 0.0 2.3e-62 209.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) RNA_pol_Rpb8 PF03870.10 XP_011273884.1 - 7.4e-29 100.6 0.2 8.1e-29 100.5 0.2 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 Zn_clus PF00172.13 XP_011273885.1 - 2.1e-07 30.6 18.3 2.1e-07 30.6 12.7 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3672 PF12421.3 XP_011273885.1 - 0.077 13.1 0.8 0.39 10.8 0.5 2.1 1 1 0 1 1 1 0 Fibronectin type III protein DPPIV_N PF00930.16 XP_011273886.1 - 4.8e-93 311.5 13.7 6.7e-93 311.0 9.5 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 XP_011273886.1 - 9e-51 172.1 0.8 1.7e-50 171.2 0.5 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 XP_011273886.1 - 3.4e-07 30.1 0.0 6.7e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 XP_011273886.1 - 4.7e-06 26.2 0.0 9.2e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.2 XP_011273886.1 - 0.0026 17.6 0.0 0.033 14.0 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family SpoIIIAH PF12685.2 XP_011273886.1 - 0.0099 15.3 1.0 0.02 14.3 0.7 1.5 1 0 0 1 1 1 1 SpoIIIAH-like protein DUF4199 PF13858.1 XP_011273886.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Trypan_PARP PF05887.6 XP_011273886.1 - 1.4 8.7 14.8 2.7 7.8 10.3 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF3752 PF12572.3 XP_011273887.1 - 5 7.2 12.4 86 3.2 8.6 2.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3752) Peptidase_C37 PF05416.7 XP_011273887.1 - 7.2 4.7 6.6 8.6 4.5 4.6 1.2 1 0 0 1 1 1 0 Southampton virus-type processing peptidase DPPIV_N PF00930.16 XP_011273888.1 - 1.2e-91 306.9 4.6 1.8e-91 306.3 3.2 1.3 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 XP_011273888.1 - 3e-46 157.3 1.4 4.9e-46 156.6 1.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.15 XP_011273888.1 - 4.5e-05 22.9 0.0 0.00011 21.7 0.0 1.6 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 XP_011273888.1 - 8.3e-05 22.3 0.0 0.00018 21.2 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 XP_011273888.1 - 0.0032 17.3 0.0 0.096 12.5 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family 3-HAO PF06052.7 XP_011273889.1 - 2.4e-64 215.3 0.1 2.7e-64 215.1 0.1 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 XP_011273889.1 - 2.9e-08 33.0 0.0 4.3e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Nudix_N_2 PF14803.1 XP_011273889.1 - 3.6e-05 23.3 1.2 0.31 10.7 0.2 2.7 2 0 0 2 2 2 2 Nudix N-terminal Cupin_1 PF00190.17 XP_011273889.1 - 0.0002 20.8 0.0 0.00031 20.1 0.0 1.3 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 XP_011273889.1 - 0.0015 18.2 0.0 0.0023 17.6 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.7 XP_011273889.1 - 0.019 14.3 0.0 0.041 13.2 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF861) DZR PF12773.2 XP_011273889.1 - 0.042 13.6 2.1 0.059 13.2 0.8 1.8 2 0 0 2 2 2 0 Double zinc ribbon Rpr2 PF04032.11 XP_011273889.1 - 0.068 13.0 0.3 1 9.2 0.4 2.2 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Cupin_6 PF12852.2 XP_011273889.1 - 0.089 12.4 0.0 0.092 12.3 0.0 1.2 1 0 0 1 1 1 0 Cupin DUF1255 PF06865.6 XP_011273889.1 - 0.12 12.6 0.0 1.3 9.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1255) DUF3973 PF13119.1 XP_011273889.1 - 0.31 10.9 1.7 0.63 10.0 1.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3973) zinc_ribbon_2 PF13240.1 XP_011273889.1 - 2.9 7.4 5.8 7.2 6.2 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 XP_011273889.1 - 5.1 6.4 7.6 4.8 6.5 0.1 2.6 3 0 0 3 3 3 0 zinc-ribbon domain ADK_lid PF05191.9 XP_011273889.1 - 5.8 6.6 6.3 24 4.7 0.2 2.9 3 0 0 3 3 3 0 Adenylate kinase, active site lid Mvb12 PF09452.5 XP_011273890.1 - 4.7e-06 26.6 0.1 6.7e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 ESCRT-I subunit Mvb12 tRNA-synt_1g PF09334.6 XP_011273891.1 - 3.3e-142 473.7 0.1 4.7e-142 473.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) MetRS-N PF09635.5 XP_011273891.1 - 1.3e-08 35.2 0.1 4e-08 33.6 0.1 1.9 1 0 0 1 1 1 1 MetRS-N binding domain Pkinase PF00069.20 XP_011273891.1 - 2e-07 30.4 0.0 4e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain tRNA-synt_1 PF00133.17 XP_011273891.1 - 7.9e-07 27.4 0.8 0.0014 16.6 0.0 3.1 2 1 1 3 3 3 2 tRNA synthetases class I (I, L, M and V) Kdo PF06293.9 XP_011273891.1 - 5.3e-06 25.6 0.0 1.2e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 XP_011273891.1 - 0.0049 15.9 0.0 0.01 14.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 XP_011273891.1 - 0.023 14.0 0.0 0.059 12.7 0.0 1.6 1 0 0 1 1 1 0 RIO1 family EcKinase PF02958.15 XP_011273891.1 - 0.039 13.0 0.0 0.075 12.1 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase APH PF01636.18 XP_011273891.1 - 0.2 11.3 0.1 0.67 9.6 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family DZR PF12773.2 XP_011273891.1 - 0.38 10.5 2.7 0.78 9.5 1.9 1.4 1 0 0 1 1 1 0 Double zinc ribbon TSC22 PF01166.13 XP_011273892.1 - 0.18 11.8 2.2 0.27 11.2 1.5 1.5 1 1 0 1 1 1 0 TSC-22/dip/bun family S_100 PF01023.14 XP_011273892.1 - 0.56 9.5 4.7 0.46 9.8 0.3 2.4 2 1 0 2 2 2 0 S-100/ICaBP type calcium binding domain HHH PF00633.18 XP_011273893.1 - 0.098 12.3 0.1 0.26 11.0 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif CobT PF06213.7 XP_011273893.1 - 0.4 9.7 11.6 0.58 9.2 8.0 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF908 PF06012.7 XP_011273893.1 - 0.56 9.4 3.2 0.71 9.1 2.2 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Zn_clus PF00172.13 XP_011273894.1 - 6.2e-07 29.2 14.1 1e-06 28.4 9.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SPO22 PF08631.5 XP_011273895.1 - 1.6e-30 106.1 12.7 2.9e-24 85.6 0.7 4.1 3 2 1 4 4 4 2 Meiosis protein SPO22/ZIP4 like TPR_2 PF07719.12 XP_011273895.1 - 0.0017 18.0 0.2 1.3 9.1 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 XP_011273895.1 - 0.01 15.9 0.4 2.4 8.3 0.0 3.2 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 XP_011273895.1 - 0.035 14.0 0.4 2.3 8.2 0.0 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 XP_011273895.1 - 0.05 13.2 0.8 1.3 8.7 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat PPR PF01535.15 XP_011273895.1 - 0.31 11.1 5.5 17 5.6 0.0 4.1 5 0 0 5 5 5 0 PPR repeat APH PF01636.18 XP_011273896.1 - 2.5e-09 37.2 0.0 5.2e-09 36.1 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 XP_011273896.1 - 0.00061 18.8 0.0 0.0012 17.9 0.0 1.4 1 0 0 1 1 1 1 Fructosamine kinase HORMA PF02301.13 XP_011273898.1 - 2e-48 164.6 1.6 2.8e-48 164.1 0.1 2.0 2 0 0 2 2 2 1 HORMA domain PHD PF00628.24 XP_011273898.1 - 5 6.8 12.8 9 6.0 8.9 1.4 1 0 0 1 1 1 0 PHD-finger Peptidase_M24 PF00557.19 XP_011273899.1 - 4.9e-46 156.9 0.0 7.5e-46 156.3 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 XP_011273899.1 - 2.6e-28 98.0 0.0 4.5e-28 97.2 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain PCI PF01399.22 XP_011273900.1 - 5.3e-06 26.7 1.6 1.1e-05 25.7 0.1 2.3 2 1 0 2 2 2 1 PCI domain PPR_2 PF13041.1 XP_011273901.1 - 1.4e-17 63.4 0.2 5.4e-09 35.8 0.0 3.3 4 0 0 4 4 4 2 PPR repeat family PPR_3 PF13812.1 XP_011273901.1 - 0.008 16.3 0.0 30 5.2 0.0 4.5 4 0 0 4 4 4 1 Pentatricopeptide repeat domain PPR PF01535.15 XP_011273901.1 - 0.058 13.3 0.4 77 3.5 0.0 4.3 4 0 0 4 4 4 0 PPR repeat Sld5 PF05916.6 XP_011273901.1 - 0.081 13.2 0.1 0.4 10.9 0.0 2.3 2 0 0 2 2 2 0 GINS complex protein WD40 PF00400.27 XP_011273902.1 - 4.7e-22 76.9 16.1 2.2e-06 27.3 0.3 6.4 5 1 0 5 5 5 4 WD domain, G-beta repeat PQQ_3 PF13570.1 XP_011273902.1 - 0.0064 16.7 0.0 1.6 9.0 0.0 3.8 3 1 1 4 4 4 1 PQQ-like domain HMGL-like PF00682.14 XP_011273903.1 - 9.5e-73 244.7 0.9 6.2e-72 242.0 0.1 2.2 2 0 0 2 2 2 1 HMGL-like SNF2_N PF00176.18 XP_011273903.1 - 6.5e-37 126.9 0.0 7.4e-36 123.4 0.0 2.5 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 XP_011273903.1 - 1.1e-05 25.2 0.0 3.1e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Cullin PF00888.17 XP_011273904.1 - 6.6e-159 530.1 23.2 8.5e-159 529.8 16.1 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 XP_011273904.1 - 5e-27 93.5 3.6 5e-27 93.5 2.5 2.1 2 0 0 2 2 2 1 Cullin protein neddylation domain Aminotran_1_2 PF00155.16 XP_011273905.1 - 2.3e-40 138.6 0.0 4.2e-40 137.8 0.0 1.3 2 0 0 2 2 2 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 XP_011273905.1 - 0.15 11.1 0.0 0.29 10.2 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase Gaa1 PF04114.9 XP_011273906.1 - 5.9e-100 335.3 18.7 5.2e-95 319.0 0.3 3.1 1 1 0 2 2 2 2 Gaa1-like, GPI transamidase component CPSF100_C PF13299.1 XP_011273907.1 - 1.1e-34 119.9 2.0 1.1e-34 119.9 1.4 3.0 3 0 0 3 3 3 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 XP_011273907.1 - 1.7e-15 57.0 0.0 9e-15 54.7 0.0 2.3 2 0 0 2 2 2 1 Beta-Casp domain Ndufs5 PF10200.4 XP_011273908.1 - 2.9e-05 23.9 0.1 3.9e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Cmc1 PF08583.5 XP_011273908.1 - 0.0033 17.1 1.1 0.0045 16.7 0.8 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 XP_011273908.1 - 0.0079 16.0 0.2 0.52 10.3 0.0 2.2 2 0 0 2 2 2 1 CHCH domain COX6B PF02297.12 XP_011273908.1 - 0.0095 15.9 0.6 0.0095 15.9 0.4 2.1 1 1 1 2 2 2 1 Cytochrome oxidase c subunit VIb DUF3128 PF11326.3 XP_011273908.1 - 0.014 15.5 1.4 0.047 13.8 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3128) Pet191_N PF10203.4 XP_011273908.1 - 0.08 12.9 0.6 0.12 12.3 0.4 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Pox_A3L PF05288.6 XP_011273908.1 - 0.098 12.3 0.1 0.16 11.7 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A3L Protein zf-CCHC PF00098.18 XP_011273909.1 - 7.2e-06 25.6 1.0 7.2e-06 25.6 0.7 2.3 2 0 0 2 2 2 1 Zinc knuckle KH_1 PF00013.24 XP_011273909.1 - 1.6e-05 24.4 0.0 3.2e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 XP_011273909.1 - 5.1e-05 22.8 0.1 0.0001 21.8 0.1 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.1 XP_011273909.1 - 0.00035 20.2 9.4 0.05 13.3 1.4 2.5 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.1 XP_011273909.1 - 0.014 14.8 0.3 0.014 14.8 0.2 2.7 2 1 1 3 3 3 0 Zinc knuckle zf-CCHC_4 PF14392.1 XP_011273909.1 - 0.07 12.8 5.7 1.4 8.6 0.2 2.4 2 0 0 2 2 2 0 Zinc knuckle eIF3g PF12353.3 XP_011273909.1 - 1.4 8.8 6.4 1.3 8.9 2.7 2.0 1 1 1 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G HAT PF02184.11 XP_011273910.1 - 6.9e-23 80.0 41.7 1.1e-05 25.1 0.4 11.3 11 1 0 11 11 11 6 HAT (Half-A-TPR) repeat TPR_14 PF13428.1 XP_011273910.1 - 1.8e-22 77.7 0.0 0.0096 16.4 0.0 9.4 7 2 3 10 10 9 4 Tetratricopeptide repeat TPR_19 PF14559.1 XP_011273910.1 - 4.2e-16 59.0 0.0 0.00033 20.9 0.0 4.7 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 XP_011273910.1 - 3.1e-15 56.3 0.4 9e-05 23.0 0.0 6.0 6 1 1 7 7 5 2 Tetratricopeptide repeat Suf PF05843.9 XP_011273910.1 - 6.3e-13 49.0 29.9 0.00039 20.2 0.9 6.0 1 1 3 5 5 5 5 Suppressor of forked protein (Suf) TPR_17 PF13431.1 XP_011273910.1 - 7.6e-09 35.0 0.4 0.00078 19.4 0.0 5.8 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.1 XP_011273910.1 - 2e-06 27.3 0.4 0.39 10.4 0.0 5.6 5 1 1 6 6 6 1 TPR repeat TPR_6 PF13174.1 XP_011273910.1 - 1.1e-05 25.5 7.7 0.79 10.3 0.0 7.5 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_2 PF07719.12 XP_011273910.1 - 0.00012 21.6 10.7 0.3 11.0 0.0 7.2 10 0 0 10 10 8 1 Tetratricopeptide repeat TPR_8 PF13181.1 XP_011273910.1 - 0.00013 21.4 1.0 24 5.0 0.0 6.5 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_12 PF13424.1 XP_011273910.1 - 0.0003 20.6 0.4 1.4 8.8 0.1 5.3 5 1 0 5 5 5 1 Tetratricopeptide repeat NRDE-2 PF08424.5 XP_011273910.1 - 0.0017 17.3 27.8 0.026 13.4 1.0 5.6 2 2 4 6 6 6 3 NRDE-2, necessary for RNA interference U3_assoc_6 PF08640.6 XP_011273910.1 - 0.0072 16.0 2.4 0.0072 16.0 1.6 7.2 7 2 2 9 9 9 1 U3 small nucleolar RNA-associated protein 6 c-SKI_SMAD_bind PF08782.5 XP_011273910.1 - 4.2 7.5 7.8 40 4.4 0.0 4.5 4 2 2 6 6 6 0 c-SKI Smad4 binding domain Methyltransf_26 PF13659.1 XP_011273911.1 - 3e-12 46.5 0.0 4.1e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 XP_011273911.1 - 4e-11 42.5 0.0 5.7e-11 42.0 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 XP_011273911.1 - 2.1e-07 30.6 0.0 3e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.7 XP_011273911.1 - 0.00036 20.1 0.0 0.0006 19.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Met_10 PF02475.11 XP_011273911.1 - 0.0012 18.4 0.0 0.0018 17.9 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein PrmA PF06325.8 XP_011273911.1 - 0.0031 16.6 0.0 0.015 14.4 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.4 XP_011273911.1 - 0.0035 16.8 0.0 0.007 15.8 0.0 1.5 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_18 PF12847.2 XP_011273911.1 - 0.0057 17.2 0.0 0.01 16.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 XP_011273911.1 - 0.0072 16.7 0.0 0.042 14.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.14 XP_011273911.1 - 0.017 14.6 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.1 XP_011273911.1 - 0.038 14.3 0.0 0.36 11.2 0.0 2.3 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_24 PF13578.1 XP_011273911.1 - 0.13 13.1 0.0 0.22 12.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Pentapeptide_2 PF01469.13 XP_011273912.1 - 0.00017 21.1 0.7 0.00042 19.8 0.5 1.6 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) Pkinase PF00069.20 XP_011273913.1 - 4.7e-72 242.2 0.2 1.5e-71 240.6 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011273913.1 - 3.7e-34 117.9 0.0 9e-34 116.7 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 XP_011273913.1 - 1.8e-05 23.8 0.3 0.16 10.9 0.0 2.8 2 1 0 3 3 3 2 Kinase-like WD40 PF00400.27 XP_011273913.1 - 0.065 13.1 0.2 6.6 6.7 0.0 2.8 2 0 0 2 2 2 0 WD domain, G-beta repeat Sigma70_ner PF04546.8 XP_011273913.1 - 0.069 12.7 4.9 0.12 11.9 3.4 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Myc_N PF01056.13 XP_011273913.1 - 0.21 10.7 4.7 0.38 9.8 3.3 1.3 1 0 0 1 1 1 0 Myc amino-terminal region CENP-B_dimeris PF09026.5 XP_011273913.1 - 1 9.6 15.0 2.5 8.3 10.4 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 XP_011273913.1 - 2.9 7.3 10.9 5.7 6.4 7.6 1.4 1 0 0 1 1 1 0 Nucleoplasmin AAA_17 PF13207.1 XP_011273914.1 - 5.8e-09 36.8 0.1 2.1e-08 34.9 0.0 2.0 2 1 0 2 2 2 1 AAA domain PRK PF00485.13 XP_011273914.1 - 3.5e-06 26.7 0.0 0.021 14.3 0.0 2.2 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 XP_011273914.1 - 2.6e-05 24.5 0.8 5.9e-05 23.3 0.2 1.9 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 XP_011273914.1 - 7.5e-05 21.9 0.0 0.00012 21.3 0.0 1.2 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 XP_011273914.1 - 8.8e-05 22.6 0.2 0.00028 21.0 0.0 1.9 2 0 0 2 2 1 1 RNA helicase AAA_33 PF13671.1 XP_011273914.1 - 0.00011 22.1 0.0 0.00018 21.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 XP_011273914.1 - 0.00016 21.7 0.0 0.00025 21.1 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain G-alpha PF00503.15 XP_011273914.1 - 0.00019 20.2 0.0 0.00019 20.2 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit AAA_5 PF07728.9 XP_011273914.1 - 0.00038 20.1 0.0 0.00087 19.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.24 XP_011273914.1 - 0.00049 20.2 0.0 0.001 19.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 XP_011273914.1 - 0.00051 19.7 0.0 0.00093 18.8 0.0 1.4 1 0 0 1 1 1 1 NACHT domain KTI12 PF08433.5 XP_011273914.1 - 0.00061 19.0 0.0 0.001 18.3 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_19 PF13245.1 XP_011273914.1 - 0.0016 18.1 0.0 0.0031 17.2 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 XP_011273914.1 - 0.0022 18.1 0.0 0.005 16.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain 6PF2K PF01591.13 XP_011273914.1 - 0.0026 16.8 0.0 0.0052 15.8 0.0 1.5 1 0 0 1 1 1 1 6-phosphofructo-2-kinase NB-ARC PF00931.17 XP_011273914.1 - 0.0029 16.5 0.0 0.005 15.7 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain Zeta_toxin PF06414.7 XP_011273914.1 - 0.0039 16.2 0.0 0.0063 15.6 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_29 PF13555.1 XP_011273914.1 - 0.0049 16.3 0.0 0.0089 15.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SE PF00437.15 XP_011273914.1 - 0.007 15.2 0.0 0.014 14.3 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein MMR_HSR1 PF01926.18 XP_011273914.1 - 0.013 15.3 0.0 0.029 14.3 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Miro PF08477.8 XP_011273914.1 - 0.015 15.7 0.1 0.051 14.0 0.1 1.9 2 0 0 2 2 1 0 Miro-like protein NTPase_1 PF03266.10 XP_011273914.1 - 0.029 14.0 0.0 0.063 12.9 0.0 1.5 1 0 0 1 1 1 0 NTPase MobB PF03205.9 XP_011273914.1 - 0.03 14.0 0.1 0.16 11.6 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ADK PF00406.17 XP_011273914.1 - 0.034 14.0 0.0 0.062 13.1 0.0 1.5 1 0 0 1 1 1 0 Adenylate kinase AAA_28 PF13521.1 XP_011273914.1 - 0.043 13.7 0.0 0.063 13.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 XP_011273914.1 - 0.045 13.2 0.0 0.076 12.5 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase APS_kinase PF01583.15 XP_011273914.1 - 0.049 13.2 0.1 0.13 11.9 0.0 1.7 2 0 0 2 2 2 0 Adenylylsulphate kinase Sigma54_activat PF00158.21 XP_011273914.1 - 0.051 13.0 0.0 0.096 12.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain CPT PF07931.7 XP_011273914.1 - 0.052 13.1 0.1 0.094 12.3 0.0 1.4 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein ABC_tran PF00005.22 XP_011273914.1 - 0.067 13.4 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_14 PF13173.1 XP_011273914.1 - 0.093 12.6 0.2 0.41 10.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 XP_011273914.1 - 0.12 11.9 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein DUF3987 PF13148.1 XP_011273914.1 - 0.14 10.6 0.0 0.21 10.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) AAA_30 PF13604.1 XP_011273914.1 - 0.18 11.3 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain ETF_alpha PF00766.14 XP_011273915.1 - 1.4e-35 120.7 1.1 2e-35 120.2 0.2 1.7 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.16 XP_011273915.1 - 1.3e-30 106.3 0.0 2.1e-30 105.5 0.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain CorA PF01544.13 XP_011273916.1 - 1.1e-30 106.7 14.9 3e-23 82.3 7.1 3.4 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein YjgP_YjgQ PF03739.9 XP_011273916.1 - 0.082 11.6 0.1 0.082 11.6 0.1 2.0 2 1 0 2 2 2 0 Predicted permease YjgP/YjgQ family Pkinase PF00069.20 XP_011273918.1 - 4.7e-48 163.5 0.1 6.4e-48 163.1 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011273918.1 - 1.7e-26 92.8 0.0 2.4e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 XP_011273918.1 - 5.7e-07 28.7 0.0 7.6e-07 28.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 XP_011273918.1 - 0.00085 18.2 0.0 0.0017 17.2 0.0 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.18 XP_011273918.1 - 0.016 14.9 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 XP_011273918.1 - 0.065 12.2 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Thioredoxin PF00085.15 XP_011273920.1 - 8.8e-21 73.5 0.0 1.1e-20 73.2 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 XP_011273920.1 - 5.7e-05 23.1 0.1 0.00025 21.1 0.0 1.9 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_7 PF13899.1 XP_011273920.1 - 0.00017 21.4 0.0 0.00025 20.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 XP_011273920.1 - 0.0019 18.3 0.0 0.011 15.9 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.5 XP_011273920.1 - 0.078 12.5 0.1 0.68 9.4 0.0 1.9 1 1 1 2 2 2 0 Redoxin DUF2847 PF11009.3 XP_011273920.1 - 0.13 11.9 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) Thioredoxin PF00085.15 XP_011273921.1 - 8e-13 47.9 0.0 9.7e-13 47.6 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 XP_011273921.1 - 0.00034 20.7 0.0 0.00042 20.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin PF00085.15 XP_011273922.1 - 0.00021 20.9 0.0 0.0003 20.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 XP_011273922.1 - 0.078 13.1 0.0 0.15 12.2 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_7 PF13899.1 XP_011273922.1 - 0.13 12.3 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like UCH PF00443.24 XP_011273923.1 - 8.9e-17 61.0 9.6 1.8e-16 60.0 6.6 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 XP_011273923.1 - 5.3e-12 45.6 0.1 1.1e-11 44.6 0.1 1.5 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein JAB PF01398.16 XP_011273924.1 - 3.4e-34 117.0 0.2 3.4e-34 117.0 0.1 2.4 2 1 1 3 3 3 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 XP_011273924.1 - 9.4e-25 86.9 3.9 2e-24 85.8 2.7 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 XP_011273924.1 - 6.3e-09 35.3 0.0 1e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UvrD-helicase PF00580.16 XP_011273924.1 - 0.022 14.0 0.2 0.026 13.8 0.1 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain DUF2870 PF11069.3 XP_011273924.1 - 0.091 12.8 1.7 0.15 12.0 0.4 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2870) Zn_clus PF00172.13 XP_011273925.1 - 3.6e-08 33.1 18.2 6.2e-08 32.4 12.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2439 PF10382.4 XP_011273926.1 - 5.3e-21 74.6 2.5 5.3e-21 74.6 1.7 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2439) Transaldolase PF00923.14 XP_011273927.1 - 1.5e-93 313.0 3.0 1.7e-93 312.9 2.1 1.0 1 0 0 1 1 1 1 Transaldolase DUF1769 PF08588.5 XP_011273928.1 - 3.5e-23 81.2 2.4 4.6e-23 80.9 0.8 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1769) zf-C2H2 PF00096.21 XP_011273929.1 - 1.3e-08 34.7 11.2 2.6e-05 24.2 0.7 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 XP_011273929.1 - 4.5e-07 29.7 11.1 0.0016 18.6 0.4 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger DUF1283 PF06932.6 XP_011273929.1 - 0.016 15.2 3.0 0.83 9.7 0.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1283) MAP PF03642.8 XP_011273929.1 - 0.11 12.7 4.4 4.4 7.6 0.1 2.7 2 0 0 2 2 2 0 MAP domain zf-H2C2_2 PF13465.1 XP_011273929.1 - 0.45 10.8 15.0 1.8 9.0 0.3 4.4 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2_jaz PF12171.3 XP_011273929.1 - 0.8 9.9 5.9 1.1 9.4 0.4 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Desulfoferrod_N PF06397.7 XP_011273929.1 - 1.7 8.1 3.1 2.2 7.7 0.3 2.1 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain AhpC-TSA PF00578.16 XP_011273930.1 - 4.5e-35 120.0 0.0 5.9e-35 119.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 XP_011273930.1 - 3.9e-13 49.1 0.0 4.7e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 XP_011273930.1 - 2.7e-11 42.9 0.0 4.8e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Ribosomal_S3Ae PF01015.13 XP_011273931.1 - 5.9e-77 257.4 7.4 7.1e-77 257.1 5.1 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family DUF2121 PF09894.4 XP_011273931.1 - 0.013 14.8 1.3 0.036 13.3 0.5 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2121) SpoVIF PF14069.1 XP_011273931.1 - 0.043 13.5 2.7 3 7.6 1.2 2.5 2 0 0 2 2 2 0 Stage VI sporulation protein F CAT_RBD PF03123.10 XP_011273931.1 - 0.043 13.5 0.0 0.095 12.4 0.0 1.5 1 0 0 1 1 1 0 CAT RNA binding domain DUF2624 PF11116.3 XP_011273931.1 - 0.15 12.6 2.7 2.7 8.5 1.9 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2624) IlvC PF01450.14 XP_011273932.1 - 4.7e-46 156.3 0.0 1.1e-45 155.1 0.0 1.6 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvN PF07991.7 XP_011273932.1 - 1.2e-45 154.8 0.0 1.8e-45 154.2 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain MFS_1 PF07690.11 XP_011273933.1 - 3.6e-28 98.2 20.6 3.6e-28 98.2 14.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Bac_rhodopsin PF01036.13 XP_011273934.1 - 7.5e-48 162.7 18.7 9.6e-48 162.4 13.0 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein PAP2_3 PF14378.1 XP_011273934.1 - 5.6 6.4 9.5 6.1 6.3 0.1 3.1 1 1 1 3 3 3 0 PAP2 superfamily MFS_1 PF07690.11 XP_011273935.1 - 4e-21 75.1 21.5 4e-21 75.1 14.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DNA_pol_B_palm PF14792.1 XP_011273936.1 - 1.4e-25 89.5 0.0 4.5e-25 87.8 0.0 1.9 2 0 0 2 2 2 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.4 XP_011273936.1 - 1.3e-19 69.4 0.0 3.9e-19 67.9 0.0 1.9 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_thumb PF14791.1 XP_011273936.1 - 9.6e-18 63.6 0.0 2.9e-17 62.1 0.0 1.9 2 0 0 2 2 2 1 DNA polymerase beta thumb HHH_8 PF14716.1 XP_011273936.1 - 4.8e-13 49.0 0.8 1.6e-12 47.3 0.3 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_5 PF14520.1 XP_011273936.1 - 0.00094 19.3 0.0 0.03 14.4 0.0 2.6 2 0 0 2 2 2 1 Helix-hairpin-helix domain BRCT PF00533.21 XP_011273936.1 - 0.0014 18.7 0.8 0.0046 17.0 0.1 2.3 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain NTP_transf_2 PF01909.18 XP_011273936.1 - 0.0054 17.0 0.0 0.017 15.4 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain Pet20 PF08692.5 XP_011273936.1 - 0.065 13.1 0.0 0.27 11.1 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial protein Pet20 PGK PF00162.14 XP_011273937.1 - 1.6e-151 504.2 0.3 1.8e-151 504.1 0.2 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Nucleic_acid_bd PF13820.1 XP_011273937.1 - 0.11 12.0 0.0 0.36 10.4 0.0 1.8 2 0 0 2 2 2 0 Putative nucleic acid-binding region Apolipoprotein PF01442.13 XP_011273937.1 - 0.18 11.2 0.1 0.47 9.9 0.1 1.4 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF3342 PF11822.3 XP_011273937.1 - 0.22 10.6 0.0 0.35 9.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3342) Peptidase_M1 PF01433.15 XP_011273938.1 - 1.1e-117 393.4 7.0 2.6e-117 392.1 4.8 1.7 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 XP_011273938.1 - 7e-73 245.6 0.3 1.1e-72 244.9 0.2 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 XP_011273938.1 - 1.3e-15 57.6 0.0 2.5e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily DUF1360 PF07098.6 XP_011273938.1 - 0.14 11.8 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1360) Frag1 PF10277.4 XP_011273939.1 - 1.1e-41 142.6 9.2 1.1e-41 142.6 6.4 3.1 3 1 0 3 3 3 1 Frag1/DRAM/Sfk1 family Exo_endo_phos PF03372.18 XP_011273939.1 - 2.7e-05 24.2 0.0 5.8e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Citrate_synt PF00285.16 XP_011273940.1 - 4.4e-101 338.1 0.0 5.2e-101 337.9 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase TIP120 PF08623.5 XP_011273941.1 - 9e-21 74.1 1.4 9e-21 74.1 0.9 4.3 4 0 0 4 4 4 2 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.1 XP_011273941.1 - 6.3e-09 36.0 0.7 0.0055 16.9 0.1 5.3 6 0 0 6 6 6 2 HEAT repeats HEAT PF02985.17 XP_011273941.1 - 8.4e-06 25.4 0.6 0.067 13.2 0.0 6.6 8 0 0 8 8 8 1 HEAT repeat DUF2435 PF10363.4 XP_011273941.1 - 0.00064 19.5 10.0 0.00078 19.2 0.6 4.8 4 0 0 4 4 4 1 Protein of unknown function (DUF2435) V-ATPase_H_C PF11698.3 XP_011273941.1 - 0.005 16.7 3.3 0.0085 16.0 0.2 3.2 3 0 0 3 3 3 1 V-ATPase subunit H HEAT_EZ PF13513.1 XP_011273941.1 - 0.021 15.2 0.0 46 4.6 0.0 4.4 5 0 0 5 5 5 0 HEAT-like repeat DUF1546 PF07571.8 XP_011273941.1 - 0.082 13.0 0.2 3.9 7.6 0.0 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF1546) DUF2373 PF10180.4 XP_011273942.1 - 5.2e-23 80.3 1.6 1.2e-22 79.1 1.1 1.7 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) HAD PF12710.2 XP_011273943.1 - 2.2e-12 47.5 0.0 3.2e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 XP_011273943.1 - 1.7e-05 24.1 0.1 0.0013 17.9 0.0 2.2 2 0 0 2 2 2 2 Putative Phosphatase UMPH-1 PF05822.7 XP_011273943.1 - 0.00038 19.8 0.5 0.00061 19.1 0.4 1.3 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD_2 PF13419.1 XP_011273943.1 - 0.00077 19.7 0.1 0.0016 18.7 0.1 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 XP_011273943.1 - 0.079 13.3 0.8 1.2 9.5 0.6 2.1 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Peptidase_M28 PF04389.12 XP_011273944.1 - 2.2e-32 112.2 0.0 4.8e-32 111.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 XP_011273944.1 - 2.2e-05 24.0 0.0 3.6e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 XP_011273944.1 - 0.0016 17.2 0.0 0.0097 14.7 0.0 1.9 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase MatE PF01554.13 XP_011273945.1 - 1.2e-55 187.5 35.5 7.4e-31 106.9 5.3 2.4 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.1 XP_011273945.1 - 0.00028 20.6 5.3 0.00028 20.6 3.7 3.9 2 1 2 4 4 4 1 Polysaccharide biosynthesis C-terminal domain MatE PF01554.13 XP_011273946.1 - 6.2e-57 191.7 38.0 9.4e-32 109.8 5.2 2.4 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.1 XP_011273946.1 - 2.7e-05 23.9 4.2 2.7e-05 23.9 2.9 4.0 2 1 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain F-box PF00646.28 XP_011273947.1 - 0.0032 17.0 0.4 0.0092 15.6 0.2 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 XP_011273947.1 - 0.037 13.7 0.1 0.076 12.7 0.0 1.6 1 0 0 1 1 1 0 F-box-like F-box-like PF12937.2 XP_011273948.1 - 0.00097 18.8 0.1 0.0019 17.9 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 XP_011273949.1 - 0.0024 17.4 0.1 0.0071 15.9 0.0 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 XP_011273949.1 - 0.0027 17.3 0.1 0.0064 16.1 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 XP_011273949.1 - 0.016 14.8 0.4 0.064 12.9 0.1 2.1 2 0 0 2 2 2 0 F-box-like domain F-box-like PF12937.2 XP_011273950.1 - 0.00048 19.7 0.1 0.0011 18.5 0.0 1.7 1 0 0 1 1 1 1 F-box-like TauD PF02668.11 XP_011273951.1 - 4.8e-48 164.0 0.1 6.7e-48 163.5 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family PRELI PF04707.9 XP_011273953.1 - 4.2e-45 153.1 1.8 5.1e-45 152.8 1.2 1.0 1 0 0 1 1 1 1 PRELI-like family DUF4393 PF14337.1 XP_011273953.1 - 0.07 12.5 0.2 0.097 12.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4393) Fungal_trans_2 PF11951.3 XP_011273954.1 - 5.3e-89 298.4 0.0 1.1e-88 297.4 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 XP_011273954.1 - 1.1e-06 28.4 7.8 2.4e-06 27.3 5.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Bac_luciferase PF00296.15 XP_011273955.1 - 9.6e-51 172.7 0.0 1.4e-50 172.2 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase MFS_1 PF07690.11 XP_011273956.1 - 7.2e-11 41.4 26.5 2.9e-07 29.5 13.0 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF2207 PF09972.4 XP_011273956.1 - 0.3 9.6 0.0 0.3 9.6 0.0 2.7 2 1 1 3 3 3 0 Predicted membrane protein (DUF2207) DUF202 PF02656.10 XP_011273956.1 - 1.6 9.0 6.4 4.6 7.5 0.1 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF202) MFS_1 PF07690.11 XP_011273957.1 - 1.8e-20 72.9 18.2 2.1e-20 72.7 9.7 2.1 1 1 0 2 2 2 1 Major Facilitator Superfamily DUF4381 PF14316.1 XP_011273957.1 - 0.03 14.4 0.0 0.092 12.8 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Vpu PF00558.14 XP_011273957.1 - 0.17 11.4 0.1 0.17 11.4 0.1 2.1 2 0 0 2 2 2 0 Vpu protein Bac_luciferase PF00296.15 XP_011273958.1 - 1.1e-57 195.5 0.0 1.5e-57 195.0 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase GATase_2 PF00310.16 XP_011273959.1 - 2.1e-144 480.6 0.0 3e-144 480.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 XP_011273959.1 - 5e-117 390.2 0.0 7.2e-117 389.7 0.0 1.2 1 0 0 1 1 1 1 Glutamate synthase central domain Glu_synthase PF01645.12 XP_011273959.1 - 1.9e-49 168.5 0.3 4.1e-48 164.1 0.0 2.1 2 0 0 2 2 2 1 Conserved region in glutamate synthase GATase_6 PF13522.1 XP_011273959.1 - 0.02 14.8 0.0 0.076 12.9 0.0 2.0 2 0 0 2 2 2 0 Glutamine amidotransferase domain Glu_synthase PF01645.12 XP_011273960.1 - 2.2e-94 316.3 0.0 3.8e-94 315.6 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase GXGXG PF01493.14 XP_011273960.1 - 1.2e-58 197.4 0.9 2.3e-58 196.5 0.6 1.4 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 XP_011273960.1 - 6.8e-25 86.8 0.1 6.8e-25 86.8 0.1 1.8 2 0 0 2 2 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 XP_011273960.1 - 7.3e-14 52.1 0.0 5.9e-13 49.1 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 XP_011273960.1 - 1.5e-12 47.7 0.0 9.4e-09 35.5 0.0 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 XP_011273960.1 - 5.4e-11 42.9 0.0 2.1e-05 24.6 0.0 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 XP_011273960.1 - 1.7e-09 37.5 0.0 5e-09 36.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 XP_011273960.1 - 3.9e-07 29.5 0.0 6.3e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase HI0933_like PF03486.9 XP_011273960.1 - 2.7e-06 26.1 1.2 1.7e-05 23.4 0.0 2.6 3 0 0 3 3 3 1 HI0933-like protein DAO PF01266.19 XP_011273960.1 - 7e-06 25.1 2.5 1.1e-05 24.5 0.0 2.5 4 0 0 4 4 3 1 FAD dependent oxidoreductase Thi4 PF01946.12 XP_011273960.1 - 7.9e-05 21.8 0.0 0.00021 20.4 0.0 1.7 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 XP_011273960.1 - 0.00019 20.4 0.2 0.0005 19.0 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.1 XP_011273960.1 - 0.00031 20.9 0.2 0.6 10.3 0.0 3.0 3 0 0 3 3 2 1 Putative NAD(P)-binding NAD_Gly3P_dh_N PF01210.18 XP_011273960.1 - 0.00085 19.0 0.0 0.0019 17.9 0.0 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.15 XP_011273960.1 - 0.001 19.1 0.2 2.7 8.1 0.0 3.5 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase AdoHcyase_NAD PF00670.16 XP_011273960.1 - 0.0015 18.3 0.0 2.3 8.0 0.0 2.9 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 XP_011273960.1 - 0.002 17.3 0.0 0.24 10.5 0.0 3.0 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 XP_011273960.1 - 0.002 17.2 0.0 0.0056 15.8 0.0 1.8 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 XP_011273960.1 - 0.004 16.2 0.0 0.009 15.0 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain YjeF_N PF03853.10 XP_011273960.1 - 0.0046 16.5 0.2 0.046 13.3 0.0 2.4 1 1 1 2 2 2 1 YjeF-related protein N-terminus GIDA PF01134.17 XP_011273960.1 - 0.0073 15.2 0.1 0.21 10.3 0.0 2.7 2 0 0 2 2 2 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 XP_011273960.1 - 0.0092 15.5 0.0 2 7.9 0.0 2.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FMO-like PF00743.14 XP_011273960.1 - 0.011 13.9 0.0 2.9 5.9 0.0 3.0 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.1 XP_011273960.1 - 0.013 15.2 0.2 0.1 12.3 0.0 2.5 3 1 0 3 3 2 0 FAD-NAD(P)-binding F420_oxidored PF03807.12 XP_011273960.1 - 0.026 14.9 0.7 0.28 11.6 0.0 2.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 XP_011273960.1 - 0.033 14.0 0.0 0.096 12.5 0.0 1.8 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_10 PF13460.1 XP_011273960.1 - 0.039 13.9 0.2 0.16 12.0 0.1 2.1 1 1 0 1 1 1 0 NADH(P)-binding ApbA PF02558.11 XP_011273960.1 - 0.049 13.0 0.1 0.13 11.6 0.1 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.7 XP_011273960.1 - 0.21 10.4 0.1 0.4 9.5 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein 3HCDH_N PF02737.13 XP_011273960.1 - 0.37 10.4 1.3 0.55 9.8 0.0 2.0 2 0 0 2 2 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.7 XP_011273960.1 - 0.76 9.1 3.8 0.62 9.4 0.0 2.6 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, catalytic domain DUF3602 PF12223.3 XP_011273961.1 - 1.5e-21 76.5 12.7 6.5e-13 48.8 0.0 3.1 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) eIF3_subunit PF08597.5 XP_011273962.1 - 1.1e-63 215.0 17.4 3.6e-63 213.4 12.1 1.6 1 1 0 1 1 1 1 Translation initiation factor eIF3 subunit DUF664 PF04978.7 XP_011273962.1 - 1.3 9.2 4.0 0.94 9.7 1.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF664) Lipase_3 PF01764.20 XP_011273963.1 - 7.6e-22 77.4 0.0 1.5e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) FAD-oxidase_C PF02913.14 XP_011273964.1 - 3.9e-53 180.3 0.0 5.1e-53 179.9 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 XP_011273964.1 - 5.4e-36 123.1 0.1 1.4e-35 121.7 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain CENP-X PF09415.5 XP_011273965.1 - 7.5e-21 73.7 0.2 1.1e-20 73.2 0.1 1.2 1 0 0 1 1 1 1 CENP-S associating Centromere protein X CBFD_NFYB_HMF PF00808.18 XP_011273965.1 - 0.13 12.3 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Dynactin_p62 PF05502.8 XP_011273966.1 - 1.8e-24 86.4 39.1 4e-12 45.6 5.5 2.6 1 1 1 2 2 2 2 Dynactin p62 family Elf1 PF05129.8 XP_011273966.1 - 0.016 14.9 3.2 0.016 14.9 2.2 3.3 3 1 1 4 4 4 0 Transcription elongation factor Elf1 like EF-hand_1 PF00036.27 XP_011273967.1 - 6.7e-26 87.5 11.4 5.8e-06 25.2 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.1 XP_011273967.1 - 1.9e-20 71.2 9.9 1.5e-05 24.1 0.1 4.5 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 XP_011273967.1 - 6e-20 69.2 7.2 2.3e-05 23.8 0.4 4.8 3 1 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.1 XP_011273967.1 - 8.8e-20 70.6 2.3 4.7e-10 39.4 0.7 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 XP_011273967.1 - 2.5e-13 49.4 16.7 0.0029 17.1 0.8 4.6 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.2 XP_011273967.1 - 4.2e-07 29.6 10.1 0.045 13.4 0.3 4.0 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 XP_011273967.1 - 3.5e-06 27.0 0.0 0.0022 18.0 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 XP_011273967.1 - 0.045 13.6 0.1 3.7 7.5 0.0 2.9 2 1 1 3 3 3 0 EF-hand domain zf-C2H2_4 PF13894.1 XP_011273968.1 - 7.7e-06 25.8 21.0 0.0017 18.5 0.7 4.4 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.21 XP_011273968.1 - 0.0012 19.0 23.0 0.0022 18.2 1.4 4.4 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 XP_011273968.1 - 0.0044 17.2 26.2 0.016 15.4 1.1 5.2 6 0 0 6 6 6 3 Zinc-finger double domain Pneumo_M2 PF07380.6 XP_011273968.1 - 0.24 11.4 0.1 0.24 11.4 0.0 2.7 2 1 0 2 2 2 0 Pneumovirus M2 protein Tim54 PF11711.3 XP_011273969.1 - 1.9e-130 434.8 1.7 2.4e-130 434.5 1.2 1.1 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 AMPKBI PF04739.10 XP_011273970.1 - 2.3e-31 107.6 2.9 2.3e-31 107.6 2.0 3.0 3 1 0 3 3 3 1 5'-AMP-activated protein kinase beta subunit, interation domain RsgI_N PF12791.2 XP_011273970.1 - 0.089 12.4 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Anti-sigma factor N-terminus Kinesin PF00225.18 XP_011273971.1 - 4.1e-117 390.6 0.5 6.7e-117 389.9 0.4 1.4 1 0 0 1 1 1 1 Kinesin motor domain RVT_2 PF07727.9 XP_011273972.1 - 2.2e-27 95.5 1.4 5.3e-27 94.3 1.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 XP_011273972.1 - 5.8e-08 32.8 0.0 1.5e-07 31.4 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain RVT_thumb PF06817.9 XP_011273972.1 - 0.00022 20.7 0.0 0.00091 18.7 0.0 2.1 1 0 0 1 1 1 1 Reverse transcriptase thumb domain His_Phos_2 PF00328.17 XP_011273973.1 - 4.1e-42 144.7 0.0 5e-42 144.4 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Carbpep_Y_N PF05388.6 XP_011273973.1 - 0.097 12.8 0.1 0.48 10.5 0.0 2.2 2 0 0 2 2 2 0 Carboxypeptidase Y pro-peptide Rep_N PF08724.5 XP_011273974.1 - 0.091 12.2 0.1 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Rep protein catalytic domain like Cas_Cas6 PF01881.11 XP_011273975.1 - 0.045 13.9 2.9 0.094 12.9 2.0 1.5 1 0 0 1 1 1 0 CRISPR associated protein Cas6 IncFII_repA PF02387.10 XP_011273976.1 - 0.21 10.7 2.2 0.34 10.0 1.5 1.2 1 0 0 1 1 1 0 IncFII RepA protein family DUF1764 PF08576.5 XP_011273977.1 - 0.0063 17.2 6.8 0.015 16.0 4.7 1.6 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF1764) DUF4355 PF14265.1 XP_011273977.1 - 0.17 11.8 16.3 0.33 10.9 11.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) YqfQ PF14181.1 XP_011273977.1 - 1.1 9.3 7.8 2.1 8.3 5.4 1.5 1 0 0 1 1 1 0 YqfQ-like protein PBP_sp32 PF07222.7 XP_011273977.1 - 1.2 8.2 8.1 1.6 7.8 5.6 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 NARP1 PF12569.3 XP_011273977.1 - 2.4 6.8 12.0 3.3 6.3 8.3 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF1682 PF07946.9 XP_011273977.1 - 3.2 6.5 12.8 4.3 6.1 8.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) SR-25 PF10500.4 XP_011273977.1 - 5.1 6.4 17.5 8.2 5.8 12.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF2956 PF11169.3 XP_011273977.1 - 6.9 6.6 15.8 16 5.5 11.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) Bac_luciferase PF00296.15 XP_011273978.1 - 2.4e-47 161.5 0.0 3.5e-47 161.0 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Bac_luciferase PF00296.15 XP_011273979.1 - 3.4e-49 167.6 0.0 5.3e-49 167.0 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase FMO-like PF00743.14 XP_011273984.1 - 1.4e-32 112.6 6.0 1.9e-12 46.1 0.5 3.1 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 XP_011273984.1 - 1.3e-14 54.7 0.0 1.3e-09 38.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 XP_011273984.1 - 2.6e-07 30.5 0.6 4.7e-05 23.2 0.0 2.9 2 1 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 XP_011273984.1 - 3.3e-07 29.5 0.4 0.0012 17.8 0.0 2.8 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 XP_011273984.1 - 8.6e-07 29.0 0.0 2.2e-05 24.4 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 XP_011273984.1 - 4.1e-06 26.7 0.0 2.7e-05 24.0 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 XP_011273984.1 - 0.011 14.8 0.6 0.53 9.3 0.2 2.3 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.22 XP_011273984.1 - 0.022 15.1 1.7 6.4 7.2 0.0 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 XP_011273984.1 - 0.14 11.0 0.4 1.2 7.9 0.1 2.5 3 0 0 3 3 3 0 FAD dependent oxidoreductase DapH_N PF08503.5 XP_011273985.1 - 0.078 13.1 0.1 0.19 11.8 0.1 1.7 1 0 0 1 1 1 0 Tetrahydrodipicolinate succinyltransferase N-terminal RsmJ PF04378.8 XP_011273986.1 - 0.0045 16.0 0.1 0.0056 15.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA small subunit methyltransferase D, RsmJ HMG_box PF00505.14 XP_011273986.1 - 0.62 10.3 4.7 1.2 9.4 3.3 1.5 1 0 0 1 1 1 0 HMG (high mobility group) box DUF3698 PF12479.3 XP_011273987.1 - 0.12 12.4 1.3 0.18 11.9 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3698) Vps51 PF08700.6 XP_011273988.1 - 2.4e-07 30.4 2.0 2.4e-07 30.4 1.4 2.9 2 1 0 2 2 2 1 Vps51/Vps67 FliG_N PF14842.1 XP_011273988.1 - 0.0011 19.0 1.8 0.61 10.2 0.0 3.1 2 1 1 3 3 3 2 FliG N-terminal domain FYVE_2 PF02318.11 XP_011273989.1 - 0.078 12.8 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger EamA PF00892.15 XP_011273991.1 - 7.8e-25 87.3 30.2 7.3e-13 48.6 2.0 2.2 2 0 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 XP_011273991.1 - 0.00022 21.3 2.5 0.00022 21.3 1.7 3.5 1 1 1 3 3 3 2 Multidrug resistance efflux transporter UPF0060 PF02694.10 XP_011273991.1 - 0.042 13.8 11.1 0.31 11.0 3.7 2.7 2 1 0 2 2 2 0 Uncharacterised BCR, YnfA/UPF0060 family DUF1129 PF06570.6 XP_011273991.1 - 0.71 9.1 9.5 0.063 12.5 0.9 2.7 2 1 0 3 3 3 0 Protein of unknown function (DUF1129) EamA PF00892.15 XP_011273993.1 - 2.7e-26 92.0 30.1 1e-13 51.4 2.3 2.2 2 0 0 2 2 2 2 EamA-like transporter family DUF3981 PF13139.1 XP_011273993.1 - 0.01 15.8 0.2 0.01 15.8 0.2 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF3981) UPF0060 PF02694.10 XP_011273993.1 - 0.01 15.8 8.4 0.25 11.3 3.4 2.7 2 0 0 2 2 2 0 Uncharacterised BCR, YnfA/UPF0060 family EmrE PF13536.1 XP_011273993.1 - 0.03 14.5 28.5 0.62 10.2 6.4 3.5 2 1 0 2 2 2 0 Multidrug resistance efflux transporter DUF1129 PF06570.6 XP_011273993.1 - 7.8 5.7 10.2 0.39 9.9 0.8 2.6 2 1 0 3 3 3 0 Protein of unknown function (DUF1129) UAA PF08449.6 XP_011273994.1 - 1.4e-13 50.4 24.3 1.7e-13 50.2 16.8 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 XP_011273994.1 - 3.1e-09 36.6 9.4 3.1e-09 36.6 6.5 2.8 2 1 0 2 2 2 1 Triose-phosphate Transporter family Mito_carr PF00153.22 XP_011273995.1 - 1.1e-43 146.8 6.7 3.3e-19 68.3 0.3 4.7 4 1 0 4 4 4 4 Mitochondrial carrier protein GARS_A PF01071.14 XP_011273996.1 - 5.8e-84 280.4 0.0 1.2e-83 279.4 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 XP_011273996.1 - 1.4e-34 118.5 0.6 7e-34 116.2 0.0 2.6 3 0 0 3 3 3 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.17 XP_011273996.1 - 6.9e-31 107.3 0.0 1.5e-30 106.2 0.0 1.6 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 XP_011273996.1 - 1.8e-28 98.5 0.3 4.1e-28 97.3 0.2 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 XP_011273996.1 - 6.1e-17 61.6 1.6 6.1e-17 61.6 1.1 3.1 4 0 0 4 4 4 1 AIR synthase related protein, N-terminal domain ATP-grasp_4 PF13535.1 XP_011273996.1 - 2.9e-10 40.1 0.0 1.8e-09 37.6 0.0 2.3 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 XP_011273996.1 - 9.1e-10 37.7 0.0 2.1e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 XP_011273996.1 - 1.5e-06 27.6 0.0 3e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 XP_011273996.1 - 0.00019 20.8 0.2 0.00036 19.8 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.9 XP_011273996.1 - 0.0017 18.2 0.2 0.0092 15.8 0.0 2.3 2 1 0 2 2 2 1 ATP-grasp domain RimK PF08443.6 XP_011273996.1 - 0.006 16.0 0.1 0.016 14.7 0.0 1.7 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_2 PF08442.5 XP_011273996.1 - 0.025 13.9 0.1 0.053 12.9 0.1 1.5 1 0 0 1 1 1 0 ATP-grasp domain DEAD PF00270.24 XP_011273997.1 - 7.9e-42 142.6 0.1 1.4e-41 141.8 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 XP_011273997.1 - 2.3e-25 88.2 0.0 5e-25 87.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain XYPPX PF02162.12 XP_011273997.1 - 0.00079 18.9 21.0 0.00079 18.9 14.5 4.3 4 0 0 4 4 4 2 XYPPX repeat (two copies) Pkinase PF00069.20 XP_011273998.1 - 2.2e-59 200.7 0.0 7.7e-59 198.9 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011273998.1 - 1.5e-35 122.5 0.0 1.1e-29 103.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 XP_011273998.1 - 5.6e-05 22.2 0.0 0.00022 20.2 0.0 1.8 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 XP_011273998.1 - 0.00078 18.8 0.0 0.0017 17.7 0.0 1.5 1 0 0 1 1 1 1 RIO1 family DUF4536 PF15055.1 XP_011273999.1 - 0.062 13.3 5.0 1.2 9.2 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4536) WD40 PF00400.27 XP_011274000.1 - 7.2e-11 41.5 7.0 3.1e-05 23.6 0.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.3 XP_011274000.1 - 0.0026 15.9 0.2 0.0057 14.8 0.1 1.4 1 1 0 1 1 1 1 Nucleoporin Nup120/160 TauD PF02668.11 XP_011274001.1 - 1.8e-21 76.9 0.0 4e-21 75.8 0.0 1.4 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family ADH_zinc_N PF00107.21 XP_011274002.1 - 4.4e-15 55.3 0.3 8.6e-15 54.4 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase MFS_1 PF07690.11 XP_011274004.1 - 1.5e-19 69.9 10.4 2.1e-19 69.4 7.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily YqzM PF14141.1 XP_011274004.1 - 1.5 8.6 4.8 4.1 7.2 0.0 2.8 2 0 0 2 2 2 0 YqzM-like protein FliW PF02623.10 XP_011274005.1 - 0.046 13.2 0.3 0.14 11.6 0.0 1.9 2 0 0 2 2 2 0 FliW protein MFS_1 PF07690.11 XP_011274006.1 - 6.1e-20 71.2 5.7 8e-20 70.8 3.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily ResIII PF04851.10 XP_011274007.1 - 1.7e-23 83.4 1.3 5.1e-23 81.8 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 XP_011274007.1 - 2.8e-15 56.2 0.0 5.3e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 XP_011274007.1 - 1.2e-12 47.4 0.1 3.6e-12 45.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 XP_011274007.1 - 0.0065 15.2 0.0 0.015 14.0 0.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Flavi_DEAD PF07652.9 XP_011274007.1 - 0.011 15.5 0.1 0.052 13.3 0.0 2.1 2 0 0 2 2 2 0 Flavivirus DEAD domain T2SE PF00437.15 XP_011274007.1 - 0.035 13.0 0.1 0.11 11.3 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_22 PF13401.1 XP_011274007.1 - 0.042 13.9 0.2 0.33 11.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.1 XP_011274007.1 - 0.12 11.8 4.6 0.9 9.0 0.0 3.2 3 1 1 4 4 4 0 AAA domain Peptidase_C13 PF01650.13 XP_011274008.1 - 1.4e-45 155.5 0.2 2.4e-45 154.8 0.1 1.3 1 0 0 1 1 1 1 Peptidase C13 family DUF3480 PF11979.3 XP_011274008.1 - 0.077 11.6 0.2 0.14 10.7 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3480) Pkinase PF00069.20 XP_011274009.1 - 5.9e-49 166.5 0.0 1.1e-48 165.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011274009.1 - 1.3e-25 89.9 0.0 1.5e-23 83.1 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 XP_011274009.1 - 1.5e-07 30.6 0.1 3.3e-07 29.5 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 XP_011274009.1 - 0.038 13.7 0.0 0.06 13.0 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family STE PF02200.11 XP_011274010.1 - 1.3e-59 199.1 1.4 2.2e-59 198.3 1.0 1.4 1 0 0 1 1 1 1 STE like transcription factor DUF2731 PF10806.3 XP_011274011.1 - 1.6e-33 115.5 0.9 1.6e-33 115.5 0.6 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2731) GST_C_3 PF14497.1 XP_011274011.1 - 0.00087 19.7 0.0 0.0014 19.0 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Fer2_3 PF13085.1 XP_011274012.1 - 0.14 11.9 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Aa_trans PF01490.13 XP_011274013.1 - 2.3e-75 253.6 32.9 2.7e-75 253.4 22.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3392 PF11872.3 XP_011274013.1 - 3.9 7.4 12.1 0.33 10.9 1.0 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF3392) TIMELESS PF04821.9 XP_011274014.1 - 1.6e-49 168.5 0.1 5.9e-48 163.4 0.1 2.7 1 1 0 1 1 1 1 Timeless protein V_ATPase_I PF01496.14 XP_011274015.1 - 3.3e-288 957.7 10.9 3.7e-288 957.5 7.6 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Reo_sigmaC PF04582.7 XP_011274015.1 - 0.054 12.6 5.2 1.3 8.1 0.4 2.3 2 0 0 2 2 2 0 Reovirus sigma C capsid protein DegS PF05384.6 XP_011274015.1 - 0.15 11.2 6.5 4.1 6.5 0.2 3.1 2 1 0 3 3 3 0 Sensor protein DegS IncA PF04156.9 XP_011274015.1 - 0.39 10.2 6.6 0.28 10.7 0.9 2.5 2 0 0 2 2 2 0 IncA protein zf-C4H2 PF10146.4 XP_011274015.1 - 2.9 7.8 4.8 3.6 7.5 0.8 2.1 2 0 0 2 2 2 0 Zinc finger-containing protein DUF972 PF06156.8 XP_011274015.1 - 3.6 7.9 6.3 1.1 9.6 0.2 3.0 3 1 1 4 4 4 0 Protein of unknown function (DUF972) Lectin_N PF03954.9 XP_011274016.1 - 0.038 13.3 0.2 0.038 13.3 0.2 2.4 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain MFS_1 PF07690.11 XP_011274017.1 - 1.1e-30 106.6 34.7 1.1e-30 106.6 24.0 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily YjbR PF04237.8 XP_011274018.1 - 0.034 14.5 0.0 0.039 14.2 0.0 1.2 1 0 0 1 1 1 0 YjbR MFS_1 PF07690.11 XP_011274019.1 - 4.4e-29 101.2 36.7 4.4e-29 101.2 25.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 XP_011274019.1 - 0.00047 18.8 39.0 0.0071 14.9 27.0 2.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.2 XP_011274019.1 - 0.0013 18.4 0.0 0.0013 18.4 0.0 3.0 4 0 0 4 4 4 1 MFS_1 like family MFS_1 PF07690.11 XP_011274020.1 - 1.5e-32 112.7 39.3 3.2e-22 78.7 15.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 XP_011274020.1 - 7.6e-09 34.6 34.6 1.5e-05 23.7 8.0 2.5 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 XP_011274020.1 - 1.9e-05 23.2 31.9 1.9e-05 23.2 22.1 2.2 1 1 1 2 2 2 1 MFS/sugar transport protein MFS_1_like PF12832.2 XP_011274020.1 - 0.0014 18.3 0.9 0.0014 18.3 0.6 2.5 3 0 0 3 3 3 1 MFS_1 like family PhaP_Bmeg PF09602.5 XP_011274020.1 - 0.1 12.4 0.8 0.16 11.7 0.5 1.2 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Oxidored_FMN PF00724.15 XP_011274021.1 - 6.2e-76 255.5 0.0 7.6e-76 255.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family MFS_1 PF07690.11 XP_011274022.1 - 2.5e-32 111.9 39.7 1.3e-20 73.4 10.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 XP_011274022.1 - 3.3e-11 42.4 33.1 2.2e-07 29.8 7.8 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter Transglut_core PF01841.14 XP_011274022.1 - 0.069 13.3 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Transglutaminase-like superfamily DUF2034 PF10356.4 XP_011274023.1 - 2.1e-41 141.0 0.0 2.7e-41 140.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 XP_011274023.1 - 0.0016 18.2 0.1 0.0066 16.2 0.1 1.9 1 1 0 1 1 1 1 Restriction endonuclease Mer2 PF09074.5 XP_011274024.1 - 0.044 13.7 1.6 0.05 13.5 1.1 1.1 1 0 0 1 1 1 0 Mer2 DUF382 PF04037.8 XP_011274025.1 - 9.5e-56 187.1 1.0 3.3e-55 185.3 0.7 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.11 XP_011274025.1 - 5.9e-18 63.9 0.4 1.2e-17 62.9 0.3 1.6 1 0 0 1 1 1 1 PSP Ribonuclease_3 PF00636.21 XP_011274026.1 - 2.2e-16 60.2 0.0 2.2e-16 60.2 0.0 2.5 2 1 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 XP_011274026.1 - 1.7e-14 53.8 0.1 4.6e-14 52.4 0.1 1.7 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.20 XP_011274026.1 - 0.00029 21.3 0.1 0.0011 19.4 0.0 2.0 2 0 0 2 2 2 1 Double-stranded RNA binding motif FAM60A PF15396.1 XP_011274026.1 - 3.7 7.2 14.0 0.44 10.2 6.1 2.0 2 0 0 2 2 2 0 Protein Family FAM60A Ribonuclease_3 PF00636.21 XP_011274027.1 - 1.4e-20 73.8 0.1 1.3e-19 70.7 0.0 2.3 2 0 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 XP_011274027.1 - 1.8e-16 60.2 0.0 3.1e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.20 XP_011274027.1 - 6.8e-08 32.9 0.0 2e-07 31.4 0.0 1.9 1 1 0 1 1 1 1 Double-stranded RNA binding motif Molybdopterin PF00384.17 XP_011274028.1 - 2.4e-68 230.8 0.0 3.8e-35 121.4 0.0 2.2 1 1 1 2 2 2 2 Molybdopterin oxidoreductase Fer2_4 PF13510.1 XP_011274028.1 - 3.7e-19 68.2 0.8 8.5e-19 67.1 0.6 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.4 XP_011274028.1 - 1.1e-17 63.0 0.1 2.8e-17 61.6 0.1 1.8 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region DUF1982 PF09326.6 XP_011274028.1 - 1.4e-15 57.1 0.0 3.3e-15 55.9 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) Fer2 PF00111.22 XP_011274028.1 - 3.9e-07 29.7 0.8 3.9e-07 29.7 0.6 2.6 3 0 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.17 XP_011274028.1 - 0.012 15.3 0.0 0.22 11.2 0.0 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Fer4 PF00037.22 XP_011274028.1 - 0.055 13.1 1.0 3 7.5 0.2 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_19 PF06902.6 XP_011274028.1 - 0.1 12.4 1.3 1 9.2 0.9 2.4 1 1 0 1 1 1 0 Divergent 4Fe-4S mono-cluster SNF2_N PF00176.18 XP_011274029.1 - 1.6e-83 280.0 2.2 2.7e-83 279.2 0.5 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain SLIDE PF09111.5 XP_011274029.1 - 9.5e-41 138.2 2.4 9.5e-41 138.2 1.7 3.2 4 0 0 4 4 4 1 SLIDE HAND PF09110.6 XP_011274029.1 - 9.7e-30 103.2 22.9 8.1e-29 100.3 15.9 2.7 1 1 0 1 1 1 1 HAND Helicase_C PF00271.26 XP_011274029.1 - 2.3e-15 56.1 0.0 1.1e-14 53.9 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 XP_011274029.1 - 3.8e-06 26.5 0.0 9.9e-06 25.1 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Myb_DNA-binding PF00249.26 XP_011274029.1 - 0.018 15.1 0.0 0.13 12.3 0.0 2.6 2 0 0 2 2 2 0 Myb-like DNA-binding domain AAA_22 PF13401.1 XP_011274029.1 - 0.099 12.7 0.6 0.54 10.4 0.1 2.5 2 1 0 2 2 2 0 AAA domain DNA_binding_1 PF01035.15 XP_011274030.1 - 5.3e-23 80.5 0.1 8.8e-23 79.8 0.1 1.3 1 1 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain RCC1 PF00415.13 XP_011274031.1 - 4.2e-17 62.0 0.0 1.2e-07 31.7 0.0 4.6 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 XP_011274031.1 - 2e-10 40.6 2.5 2e-09 37.4 0.3 2.7 2 0 0 2 2 2 1 BTB/POZ domain RCC1_2 PF13540.1 XP_011274031.1 - 1.4e-08 34.1 0.0 1.3e-07 31.0 0.2 2.4 2 0 0 2 2 2 1 Regulator of chromosome condensation (RCC1) repeat Ank_4 PF13637.1 XP_011274031.1 - 8.7e-08 32.4 0.3 4.5e-07 30.2 0.1 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 XP_011274031.1 - 4.5e-07 29.9 0.0 0.012 15.8 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 XP_011274031.1 - 6.2e-06 26.4 0.0 1.6e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 XP_011274031.1 - 0.0028 17.7 0.8 0.65 10.4 0.1 2.9 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.25 XP_011274031.1 - 0.026 14.3 0.4 0.22 11.3 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeat NAD_binding_10 PF13460.1 XP_011274032.1 - 7.6e-12 45.6 0.2 3.1e-11 43.5 0.1 2.0 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 XP_011274032.1 - 4.3e-10 39.4 0.1 1.5e-07 31.1 0.1 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NmrA PF05368.8 XP_011274032.1 - 6.1e-09 35.4 0.2 9.3e-09 34.8 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 XP_011274032.1 - 2.1e-07 29.9 0.1 2.5e-05 23.1 0.1 2.1 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 XP_011274032.1 - 2.1e-06 26.8 0.0 0.00023 20.1 0.1 2.2 2 0 0 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.12 XP_011274032.1 - 1.1e-05 24.4 0.1 0.098 11.5 0.0 2.2 1 1 0 2 2 2 2 RmlD substrate binding domain adh_short PF00106.20 XP_011274032.1 - 1.1e-05 25.3 0.0 2e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase TrkA_N PF02254.13 XP_011274032.1 - 5.7e-05 23.1 0.8 9.5e-05 22.3 0.1 1.6 2 0 0 2 2 2 1 TrkA-N domain ApbA PF02558.11 XP_011274032.1 - 0.0017 17.8 0.1 0.0032 16.9 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA KR PF08659.5 XP_011274032.1 - 0.0026 17.4 0.8 0.0034 17.0 0.1 1.5 2 0 0 2 2 2 1 KR domain NAD_binding_2 PF03446.10 XP_011274032.1 - 0.0058 16.4 0.1 0.021 14.6 0.0 2.0 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox PF00070.22 XP_011274032.1 - 0.008 16.5 0.1 0.035 14.5 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Saccharop_dh PF03435.13 XP_011274032.1 - 0.0082 15.1 0.1 0.012 14.5 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase UDPG_MGDP_dh_N PF03721.9 XP_011274032.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Polysacc_synt_2 PF02719.10 XP_011274032.1 - 0.036 12.9 0.0 0.053 12.4 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 2-Hacid_dh_C PF02826.14 XP_011274032.1 - 0.047 12.8 0.0 0.072 12.2 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 XP_011274032.1 - 0.076 12.6 0.2 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GATase PF00117.23 XP_011274033.1 - 7.4e-47 159.2 0.0 1e-46 158.8 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.17 XP_011274033.1 - 5.6e-44 148.8 0.0 1e-43 147.9 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.8 XP_011274033.1 - 8.1e-06 25.4 0.1 0.00055 19.4 0.1 2.6 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.19 XP_011274033.1 - 0.015 14.7 0.1 0.033 13.6 0.0 1.5 1 0 0 1 1 1 0 DJ-1/PfpI family Nup160 PF11715.3 XP_011274034.1 - 4.3e-64 216.6 13.8 6.9e-64 215.9 9.6 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 TAP42 PF04177.7 XP_011274035.1 - 1.2e-90 303.9 19.2 1.3e-90 303.7 13.3 1.0 1 0 0 1 1 1 1 TAP42-like family PilJ PF13675.1 XP_011274035.1 - 0.41 10.9 2.1 1.6 9.0 0.1 2.6 3 1 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF89 PF01937.14 XP_011274036.1 - 4.2e-108 361.3 3.1 4.8e-108 361.1 2.2 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 DWNN PF08783.6 XP_011274037.1 - 6.7e-34 115.6 0.2 6.7e-34 115.6 0.1 2.5 2 0 0 2 2 2 1 DWNN domain U-box PF04564.10 XP_011274037.1 - 6.4e-07 29.2 0.9 1.2e-06 28.4 0.0 1.9 2 0 0 2 2 2 1 U-box domain zf-CCHC PF00098.18 XP_011274037.1 - 0.00012 21.8 8.6 0.0012 18.6 2.0 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.1 XP_011274037.1 - 0.00017 20.9 3.2 0.00038 19.8 2.2 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-Nse PF11789.3 XP_011274037.1 - 0.0002 20.8 0.4 0.00051 19.4 0.3 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Zn_Tnp_IS1595 PF12760.2 XP_011274037.1 - 0.0046 16.7 0.2 0.54 10.1 0.0 2.4 2 0 0 2 2 2 1 Transposase zinc-ribbon domain zf-CCHC_3 PF13917.1 XP_011274037.1 - 0.013 15.1 0.9 0.033 13.9 0.1 2.1 2 0 0 2 2 2 0 Zinc knuckle TF_Zn_Ribbon PF08271.7 XP_011274037.1 - 0.025 13.8 4.3 0.17 11.2 0.1 2.8 2 0 0 2 2 2 0 TFIIB zinc-binding DUF1610 PF07754.6 XP_011274037.1 - 0.15 12.2 0.2 0.15 12.2 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) zf-CCHC_5 PF14787.1 XP_011274037.1 - 0.91 9.0 4.1 1.5 8.3 0.4 2.5 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger F_bP_aldolase PF01116.15 XP_011274038.1 - 3.3e-95 318.4 0.0 3.7e-95 318.3 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II DUF3573 PF12097.3 XP_011274038.1 - 0.073 11.6 0.0 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) SNAP PF14938.1 XP_011274038.1 - 0.13 11.3 0.2 0.23 10.5 0.2 1.3 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP ADH_zinc_N PF00107.21 XP_011274040.1 - 4e-10 39.3 0.0 9.9e-10 38.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 XP_011274040.1 - 1.8e-06 27.6 0.0 3.3e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.16 XP_011274040.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase CRAL_TRIO PF00650.15 XP_011274041.1 - 1.7e-40 138.1 0.0 2.5e-40 137.5 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 XP_011274041.1 - 1e-13 51.1 0.8 3.4e-13 49.5 0.6 2.0 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 XP_011274041.1 - 0.0082 16.0 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain PALP PF00291.20 XP_011274042.1 - 1.8e-48 165.3 0.1 2.3e-48 165.0 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DnaJ PF00226.26 XP_011274043.1 - 9.4e-17 60.5 2.4 3.7e-16 58.5 1.6 2.1 1 0 0 1 1 1 1 DnaJ domain RRM_6 PF14259.1 XP_011274043.1 - 1.7e-05 24.6 0.0 0.0035 17.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 XP_011274043.1 - 2.5e-05 23.8 0.0 9.6e-05 21.9 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UNC45-central PF11701.3 XP_011274044.1 - 3.7e-11 42.9 3.3 1.5e-10 40.9 2.3 2.2 1 1 0 1 1 1 1 Myosin-binding striated muscle assembly central Ank_2 PF12796.2 XP_011274045.1 - 3e-44 149.2 0.1 7.9e-19 67.7 0.0 3.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 XP_011274045.1 - 2.4e-30 102.8 0.4 4e-07 29.5 0.0 6.6 6 0 0 6 6 6 4 Ankyrin repeat zf-DHHC PF01529.15 XP_011274045.1 - 1.8e-28 99.1 5.3 1.8e-28 99.1 3.7 2.3 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_5 PF13857.1 XP_011274045.1 - 2.1e-28 97.7 0.5 1.6e-09 37.6 0.0 4.5 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 XP_011274045.1 - 4.4e-25 87.5 1.2 4.4e-09 36.6 0.1 4.6 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 XP_011274045.1 - 5.5e-22 75.6 0.4 2.1e-05 24.3 0.0 6.1 6 0 0 6 6 6 3 Ankyrin repeat OSTMP1 PF09777.4 XP_011274045.1 - 0.0015 17.7 0.0 0.0031 16.7 0.0 1.5 1 0 0 1 1 1 1 Osteopetrosis-associated transmembrane protein 1 precursor DUF1744 PF08490.7 XP_011274046.1 - 1.7e-148 494.4 0.5 2.6e-148 493.8 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 XP_011274046.1 - 5.8e-63 212.7 2.1 5.8e-63 212.7 1.5 2.6 3 0 0 3 3 3 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 XP_011274046.1 - 6.4e-24 84.5 1.7 1.4e-23 83.4 1.2 1.6 1 0 0 1 1 1 1 DNA polymerase family B RNase_H_2 PF13482.1 XP_011274046.1 - 3.3e-06 26.9 0.6 3.3e-05 23.7 0.0 2.9 2 0 0 2 2 2 1 RNase_H superfamily YIF1 PF03878.10 XP_011274047.1 - 1.4e-64 217.4 8.9 1.7e-64 217.2 6.2 1.1 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 XP_011274047.1 - 0.0038 16.7 10.2 0.0084 15.6 7.0 1.6 1 1 0 1 1 1 1 Yip1 domain ING PF12998.2 XP_011274048.1 - 2e-21 76.2 2.2 2e-21 76.2 1.5 1.9 2 1 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 XP_011274048.1 - 1.3e-09 37.5 9.0 2.2e-09 36.8 6.2 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 XP_011274048.1 - 0.0017 18.4 0.3 0.0038 17.3 0.2 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain PHD_2 PF13831.1 XP_011274048.1 - 0.012 14.9 3.3 0.023 14.0 2.3 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.6 XP_011274048.1 - 1.1 9.3 4.2 2.5 8.1 2.9 1.7 1 1 0 1 1 1 0 RING-like domain DUF4112 PF13430.1 XP_011274049.1 - 8.2e-33 112.4 0.7 1.1e-32 112.1 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) HCV_core PF01542.13 XP_011274049.1 - 0.53 10.7 2.5 6.5 7.2 0.3 2.3 1 1 1 2 2 2 0 Hepatitis C virus core protein bZIP_1 PF00170.16 XP_011274050.1 - 1.8e-10 40.6 10.0 1.8e-10 40.6 6.9 2.5 2 1 0 2 2 2 1 bZIP transcription factor DUF3972 PF13118.1 XP_011274050.1 - 0.0064 16.5 0.5 0.0064 16.5 0.4 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3972) Phage_GP20 PF06810.6 XP_011274050.1 - 0.015 14.7 3.2 0.015 14.7 2.2 2.2 2 0 0 2 2 2 0 Phage minor structural protein GP20 HALZ PF02183.13 XP_011274050.1 - 0.022 14.4 1.9 0.045 13.4 1.3 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper Glutaredoxin2_C PF04399.8 XP_011274050.1 - 0.073 12.6 8.8 0.11 12.1 0.5 2.2 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain Seryl_tRNA_N PF02403.17 XP_011274050.1 - 0.13 12.2 12.9 0.83 9.6 1.6 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain PAT1 PF09770.4 XP_011274050.1 - 0.36 9.0 26.3 0.43 8.7 18.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MLANA PF14991.1 XP_011274050.1 - 0.61 10.1 4.0 4.7 7.2 0.1 2.3 2 0 0 2 2 2 0 Protein melan-A Adeno_PIX PF03955.9 XP_011274050.1 - 0.88 10.1 6.7 2.2 8.8 0.1 2.2 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) Retrotrans_gag PF03732.12 XP_011274050.1 - 0.93 9.6 13.3 0.77 9.8 0.5 2.3 2 1 0 2 2 2 0 Retrotransposon gag protein DUF3080 PF11279.3 XP_011274050.1 - 0.93 8.5 14.6 2 7.4 6.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3080) APG6 PF04111.7 XP_011274050.1 - 1.1 8.3 17.5 0.57 9.1 4.6 2.0 2 0 0 2 2 2 0 Autophagy protein Apg6 DivIVA PF05103.8 XP_011274050.1 - 1.4 8.9 20.0 0.33 11.0 1.7 2.4 2 1 0 2 2 2 0 DivIVA protein Spc24 PF08286.6 XP_011274050.1 - 2 8.1 8.3 5.2 6.8 0.0 2.4 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF972 PF06156.8 XP_011274050.1 - 3.2 8.1 13.0 2.8 8.3 1.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF972) MMPL PF03176.10 XP_011274050.1 - 3.5 6.2 4.8 6.1 5.4 3.3 1.3 1 0 0 1 1 1 0 MMPL family PLC-beta_C PF08703.5 XP_011274050.1 - 4.1 7.0 20.2 0.34 10.5 7.1 2.2 2 0 0 2 2 2 0 PLC-beta C terminal WASH-7_C PF14746.1 XP_011274050.1 - 4.9 6.7 9.0 12 5.5 0.3 2.1 2 0 0 2 2 2 0 WASH complex subunit 7, C-terminal SPT16 PF08644.6 XP_011274050.1 - 5 6.9 10.7 0.42 10.4 0.6 2.1 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) PXA PF02194.10 XP_011274050.1 - 6.5 6.2 8.8 13 5.2 0.2 2.1 2 0 0 2 2 2 0 PXA domain Tup_N PF08581.5 XP_011274050.1 - 6.7 6.9 17.2 0.81 9.9 1.9 2.4 2 0 0 2 2 2 0 Tup N-terminal Prefoldin PF02996.12 XP_011274050.1 - 6.8 6.3 13.6 1.7 8.2 0.4 2.4 2 0 0 2 2 2 0 Prefoldin subunit Nop53 PF07767.6 XP_011274050.1 - 7.3 5.4 22.1 4.8 6.0 11.2 1.9 1 1 1 2 2 2 0 Nop53 (60S ribosomal biogenesis) bZIP_2 PF07716.10 XP_011274050.1 - 9 6.2 29.3 0.075 12.8 8.9 3.6 3 1 0 3 3 3 0 Basic region leucine zipper Pkinase PF00069.20 XP_011274051.1 - 2.1e-21 76.2 0.0 3.5e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.17 XP_011274051.1 - 3.5e-09 35.9 5.8 0.19 11.9 0.0 6.7 6 0 0 6 6 6 2 HEAT repeat WD40 PF00400.27 XP_011274051.1 - 6e-08 32.2 5.0 0.0001 22.0 0.1 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat Pkinase_Tyr PF07714.12 XP_011274051.1 - 1.2e-06 27.8 0.0 1.9e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.1 XP_011274051.1 - 1.5e-05 25.1 0.2 0.12 12.6 0.0 3.5 2 1 2 4 4 4 2 HEAT repeats Kinase-like PF14531.1 XP_011274051.1 - 0.043 12.7 0.0 0.086 11.7 0.0 1.5 1 1 0 1 1 1 0 Kinase-like HEAT_EZ PF13513.1 XP_011274051.1 - 0.17 12.4 0.5 17 6.0 0.1 3.3 3 0 0 3 3 3 0 HEAT-like repeat Pkinase PF00069.20 XP_011274052.1 - 4.9e-61 206.1 0.0 6e-61 205.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011274052.1 - 4.5e-30 104.5 0.0 6e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 XP_011274052.1 - 0.034 13.8 0.0 0.058 13.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 XP_011274052.1 - 0.066 12.2 0.1 0.15 11.1 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DnaJ PF00226.26 XP_011274053.1 - 2e-13 49.8 4.6 2.4e-13 49.5 1.8 2.1 2 0 0 2 2 2 1 DnaJ domain CM_2 PF01817.16 XP_011274054.1 - 0.00024 21.1 1.4 2.3 8.3 0.2 4.1 2 1 1 3 3 3 3 Chorismate mutase type II Mito_carr PF00153.22 XP_011274055.1 - 6.4e-65 214.9 1.0 3.3e-22 78.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Vac_ImportDeg PF09783.4 XP_011274056.1 - 8.7e-67 224.0 7.4 1.5e-66 223.2 5.1 1.4 1 0 0 1 1 1 1 Vacuolar import and degradation protein DUF4482 PF14818.1 XP_011274056.1 - 1.1 9.9 7.7 0.25 12.0 2.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) Oxidored_FMN PF00724.15 XP_011274057.1 - 4.8e-76 255.9 0.0 5.8e-76 255.6 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF1887 PF09002.6 XP_011274057.1 - 0.044 12.1 0.0 0.064 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1887) Dus PF01207.12 XP_011274057.1 - 0.053 12.3 0.0 0.077 11.8 0.0 1.2 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) Oxidored_FMN PF00724.15 XP_011274058.1 - 1.6e-75 254.2 0.0 2e-75 253.9 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Oxidored_FMN PF00724.15 XP_011274059.1 - 4.9e-76 255.9 0.0 6.2e-76 255.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Oxidored_FMN PF00724.15 XP_011274060.1 - 7.9e-75 251.9 0.0 1e-74 251.5 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.12 XP_011274060.1 - 0.051 12.3 0.0 0.071 11.9 0.0 1.2 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) DUF1887 PF09002.6 XP_011274060.1 - 0.14 10.5 0.0 0.21 9.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1887) SOG2 PF10428.4 XP_011274061.1 - 2e-68 231.1 19.0 7.6e-40 136.9 4.1 3.4 2 1 1 3 3 3 2 RAM signalling pathway protein LRR_4 PF12799.2 XP_011274061.1 - 3.3e-14 52.1 26.8 2.6e-07 30.0 4.7 4.7 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 XP_011274061.1 - 6.3e-12 45.0 17.7 3.1e-08 33.2 1.6 3.7 2 1 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 XP_011274061.1 - 9.2e-08 31.0 21.9 0.034 14.1 0.8 6.7 6 0 0 6 6 6 4 Leucine Rich Repeat LRR_7 PF13504.1 XP_011274061.1 - 1.8e-07 30.2 6.3 0.4 11.0 0.0 6.0 5 0 0 5 5 5 3 Leucine rich repeat MCM PF00493.18 XP_011274062.1 - 1.4e-128 428.3 0.3 2e-128 427.8 0.2 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 XP_011274062.1 - 1.2e-24 87.0 0.0 3.3e-24 85.6 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 XP_011274062.1 - 5e-08 32.3 0.0 4.4e-07 29.2 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 XP_011274062.1 - 0.0013 18.2 0.0 0.0028 17.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 XP_011274062.1 - 0.002 17.6 0.1 0.009 15.5 0.0 2.1 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA PF00004.24 XP_011274062.1 - 0.045 13.9 0.6 0.55 10.4 0.1 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 XP_011274062.1 - 0.047 13.4 0.0 0.16 11.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) UDG PF03167.14 XP_011274063.1 - 1.2e-18 67.0 0.0 1.7e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Cmc1 PF08583.5 XP_011274064.1 - 0.00045 19.9 1.0 0.00082 19.1 0.7 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Tcf25 PF04910.9 XP_011274065.1 - 1.5e-81 274.1 0.1 2.9e-81 273.2 0.1 1.5 1 0 0 1 1 1 1 Transcriptional repressor TCF25 Nop53 PF07767.6 XP_011274065.1 - 1.5 7.7 34.9 2.5 7.0 24.2 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Stm1_N PF09598.5 XP_011274065.1 - 7.2 7.3 17.4 48 4.7 12.0 2.3 1 1 0 1 1 1 0 Stm1 Ipi1_N PF12333.3 XP_011274066.1 - 2.3e-30 104.5 0.4 7.8e-30 102.8 0.3 2.0 1 0 0 1 1 1 1 Rix1 complex component involved in 60S ribosome maturation Adaptin_N PF01602.15 XP_011274066.1 - 0.0033 15.7 2.4 0.005 15.2 1.7 1.3 1 0 0 1 1 1 1 Adaptin N terminal region FANCI_S2 PF14676.1 XP_011274066.1 - 0.0042 17.0 0.4 0.0077 16.1 0.3 1.5 1 0 0 1 1 1 1 FANCI solenoid 2 Vps35 PF03635.12 XP_011274066.1 - 0.028 12.5 2.7 0.034 12.3 1.9 1.3 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 35 Brr6_like_C_C PF10104.4 XP_011274067.1 - 1.8e-44 150.5 0.5 2.6e-44 149.9 0.4 1.3 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Cyt-b5 PF00173.23 XP_011274068.1 - 2.5e-15 56.0 0.1 1.6e-14 53.4 0.0 2.2 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.19 XP_011274068.1 - 1.7e-08 34.2 11.8 1.7e-08 34.2 8.1 2.3 1 1 1 2 2 2 1 Fatty acid desaturase zf-HIT PF04438.11 XP_011274069.1 - 3.5e-09 36.1 11.6 6e-09 35.3 8.0 1.3 1 0 0 1 1 1 1 HIT zinc finger CDC45 PF02724.9 XP_011274069.1 - 2.1 6.3 15.2 4 5.3 10.6 1.4 1 0 0 1 1 1 0 CDC45-like protein RRF PF01765.14 XP_011274070.1 - 1.5e-38 131.8 2.2 2.6e-38 131.0 1.5 1.4 1 0 0 1 1 1 1 Ribosome recycling factor ATP-synt_G PF04718.10 XP_011274070.1 - 0.1 13.2 1.4 0.27 11.9 0.3 2.2 2 1 0 2 2 2 0 Mitochondrial ATP synthase g subunit DUF2686 PF10887.3 XP_011274070.1 - 0.11 11.1 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2686) RNA_pol_Rpb1_1 PF04997.7 XP_011274070.1 - 0.12 11.6 3.7 0.13 11.4 0.1 2.0 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 1 DUF2611 PF11022.3 XP_011274070.1 - 0.53 10.4 3.7 5.5 7.1 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2611) Aldedh PF00171.17 XP_011274071.1 - 6.5e-131 436.8 0.0 7.6e-131 436.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RhoGEF PF00621.15 XP_011274072.1 - 8.4e-22 77.9 6.6 8.4e-22 77.9 4.6 2.6 3 0 0 3 3 3 1 RhoGEF domain SBDS PF01172.13 XP_011274073.1 - 5.5e-19 67.7 0.6 6.5e-19 67.5 0.4 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein PDCD2_C PF04194.8 XP_011274074.1 - 7.1e-41 139.5 1.1 6.1e-38 129.9 0.0 2.5 2 1 0 2 2 2 2 Programmed cell death protein 2, C-terminal putative domain GTP_EFTU PF00009.22 XP_011274075.1 - 2e-37 128.4 4.7 2e-37 128.4 3.2 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 XP_011274075.1 - 1.8e-28 98.6 2.9 4.9e-28 97.1 2.0 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 XP_011274075.1 - 5.9e-11 42.3 0.5 2.5e-05 24.2 0.0 3.1 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 XP_011274075.1 - 2.6e-07 30.6 0.3 2.6e-07 30.6 0.2 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase IF2_N PF04760.10 XP_011274075.1 - 3e-07 29.9 2.3 6.2e-07 28.9 0.0 2.9 3 0 0 3 3 3 1 Translation initiation factor IF-2, N-terminal region Miro PF08477.8 XP_011274075.1 - 5e-06 27.0 0.5 1.6e-05 25.4 0.3 1.8 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 XP_011274075.1 - 3.7e-05 23.0 0.1 0.00012 21.3 0.0 1.9 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 XP_011274075.1 - 0.0025 17.1 0.3 0.0059 16.0 0.2 1.6 1 0 0 1 1 1 1 Ras family SSrecog PF03531.9 XP_011274075.1 - 0.0047 16.2 0.4 0.011 15.1 0.3 1.5 1 0 0 1 1 1 1 Structure-specific recognition protein (SSRP1) PduV-EutP PF10662.4 XP_011274075.1 - 0.0093 15.4 1.0 0.0093 15.4 0.7 2.3 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Hydrolase PF00702.21 XP_011274075.1 - 0.027 14.8 0.4 0.12 12.7 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 XP_011274075.1 - 0.068 13.0 0.0 1.8 8.5 0.0 3.1 3 1 0 3 3 3 0 Haloacid dehalogenase-like hydrolase OTCace PF00185.19 XP_011274075.1 - 0.2 11.5 1.7 0.49 10.2 0.2 2.0 2 0 0 2 2 2 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Dynamin_N PF00350.18 XP_011274075.1 - 0.29 10.9 10.0 2.9 7.6 0.0 3.4 2 2 1 3 3 3 0 Dynamin family Dfp1_Him1_M PF08630.5 XP_011274076.1 - 7.5e-34 116.2 1.3 1.6e-33 115.1 0.1 2.2 1 1 0 2 2 2 1 Dfp1/Him1, central region zf-DBF PF07535.7 XP_011274076.1 - 5.2e-20 70.8 2.3 5.2e-20 70.8 1.6 1.9 2 0 0 2 2 2 1 DBF zinc finger Cache_2 PF08269.6 XP_011274076.1 - 0.23 11.4 5.2 7.7 6.5 0.0 3.3 3 0 0 3 3 3 0 Cache domain Peroxin-3 PF04882.7 XP_011274078.1 - 2.2e-116 389.1 15.0 2.5e-116 388.9 10.4 1.0 1 0 0 1 1 1 1 Peroxin-3 Sas10_Utp3 PF04000.10 XP_011274079.1 - 0.0038 17.4 1.7 0.0089 16.2 0.0 2.0 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Herpes_DNAp_acc PF04929.7 XP_011274080.1 - 0.061 12.2 0.0 0.061 12.2 0.0 2.5 2 0 0 2 2 2 0 Herpes DNA replication accessory factor Thioredoxin_7 PF13899.1 XP_011274081.1 - 9.6e-19 67.1 0.0 2e-18 66.1 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like UBX PF00789.15 XP_011274081.1 - 3.3e-14 52.6 0.2 9e-14 51.2 0.1 1.8 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 XP_011274081.1 - 5.4e-12 45.0 0.1 1.1e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain Ubiquitin_3 PF14836.1 XP_011274081.1 - 0.065 12.9 0.5 0.2 11.3 0.1 1.9 2 0 0 2 2 2 0 Ubiquitin-like domain DUF2555 PF10742.4 XP_011274081.1 - 0.27 10.9 1.5 0.43 10.2 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2555) Sec7 PF01369.15 XP_011274082.1 - 6.1e-62 208.6 1.6 6.1e-62 208.6 1.1 2.3 2 0 0 2 2 2 1 Sec7 domain ADH_zinc_N PF00107.21 XP_011274083.1 - 1.7e-31 108.4 0.0 7.5e-31 106.3 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 XP_011274083.1 - 5e-11 43.6 0.0 1.2e-10 42.3 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 XP_011274083.1 - 1.5e-09 37.6 0.0 3e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Peptidase_M29 PF02073.10 XP_011274083.1 - 0.04 12.6 0.1 0.067 11.9 0.0 1.3 1 0 0 1 1 1 0 Thermophilic metalloprotease (M29) FMO-like PF00743.14 XP_011274084.1 - 1.3e-30 106.0 0.3 1.4e-12 46.6 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 XP_011274084.1 - 8.1e-18 65.2 0.0 1.5e-16 61.0 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 XP_011274084.1 - 1.4e-12 47.6 0.0 4.8e-05 23.1 0.0 2.9 3 0 0 3 3 3 2 FAD-NAD(P)-binding K_oxygenase PF13434.1 XP_011274084.1 - 1.2e-07 31.0 1.0 0.028 13.3 0.0 3.8 3 1 1 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 XP_011274084.1 - 4.5e-06 26.6 0.0 2.3e-05 24.3 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 XP_011274084.1 - 0.00018 20.5 0.0 0.047 12.5 0.0 2.6 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 XP_011274084.1 - 0.0013 18.7 0.0 0.0046 16.9 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain SLS PF14611.1 XP_011274084.1 - 0.0065 15.9 0.0 0.015 14.6 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator ENTH PF01417.15 XP_011274085.1 - 8.4e-33 112.8 0.7 8.4e-33 112.8 0.5 2.0 2 0 0 2 2 2 1 ENTH domain PALP PF00291.20 XP_011274086.1 - 2.7e-72 243.5 0.5 3.3e-72 243.3 0.4 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 XP_011274086.1 - 5.5e-40 134.8 0.5 9.9e-27 92.3 0.0 2.6 2 1 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase DJ-1_PfpI PF01965.19 XP_011274087.1 - 5.9e-24 84.2 0.0 9.4e-24 83.5 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 XP_011274087.1 - 2e-06 27.2 0.2 5.8e-06 25.7 0.1 1.8 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family DUF4066 PF13278.1 XP_011274087.1 - 0.061 12.5 0.1 0.12 11.6 0.0 1.5 2 0 0 2 2 2 0 Putative amidotransferase Fungal_trans_2 PF11951.3 XP_011274088.1 - 6.5e-35 120.4 2.0 9.3e-35 119.9 1.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 XP_011274088.1 - 5.5e-08 32.5 8.3 1.1e-07 31.6 5.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF702 PF05142.7 XP_011274088.1 - 0.65 10.1 6.6 0.82 9.8 3.8 1.7 1 1 0 2 2 2 0 Domain of unknown function (DUF702) Cyclin PF08613.6 XP_011274089.1 - 7e-12 45.9 2.8 1.1e-11 45.3 2.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 XP_011274089.1 - 0.036 13.6 0.8 0.082 12.4 0.5 1.7 1 1 0 1 1 1 0 Cyclin, N-terminal domain XPG_N PF00752.12 XP_011274090.1 - 4.9e-36 123.0 0.0 1.3e-35 121.6 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 XP_011274090.1 - 1.7e-26 92.0 0.0 9.8e-26 89.6 0.0 2.5 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.2 XP_011274090.1 - 4.9e-05 22.9 0.0 0.00024 20.6 0.0 2.1 1 1 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.15 XP_011274090.1 - 0.0048 17.1 0.0 0.0048 17.1 0.0 2.9 3 0 0 3 3 3 1 5'-3' exonuclease, C-terminal SAM fold RNase_H2-Ydr279 PF09468.5 XP_011274091.1 - 1.8e-48 165.3 14.7 2.2e-48 165.0 10.2 1.0 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) Band_7 PF01145.20 XP_011274092.1 - 1.5e-31 109.6 0.1 2.6e-31 108.9 0.1 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 XP_011274092.1 - 0.011 15.2 0.0 0.032 13.7 0.0 1.8 1 1 0 1 1 1 0 SPFH domain-Band 7 family RecX PF02631.11 XP_011274092.1 - 0.037 14.2 0.2 0.086 13.0 0.1 1.6 1 0 0 1 1 1 0 RecX family RNase_PH PF01138.16 XP_011274093.1 - 6.8e-19 68.4 0.0 1.9e-18 67.0 0.0 1.7 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 XP_011274093.1 - 1.9e-10 40.5 0.0 4e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 RIO1 PF01163.17 XP_011274094.1 - 0.0017 17.7 2.6 0.0017 17.7 0.0 2.2 2 1 0 2 2 2 1 RIO1 family APH PF01636.18 XP_011274094.1 - 0.043 13.5 0.0 0.068 12.8 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Sulfatase_C PF14707.1 XP_011274095.1 - 0.0081 16.4 0.4 0.0089 16.3 0.3 1.1 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF342 PF03961.8 XP_011274095.1 - 0.055 11.8 2.4 0.056 11.8 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Cbl_N PF02262.11 XP_011274095.1 - 0.12 12.1 5.6 0.23 11.1 0.1 2.1 1 1 1 2 2 2 0 CBL proto-oncogene N-terminal domain 1 Sugar_tr PF00083.19 XP_011274095.1 - 0.25 9.8 0.5 0.28 9.7 0.4 1.1 1 0 0 1 1 1 0 Sugar (and other) transporter IncA PF04156.9 XP_011274095.1 - 0.27 10.8 1.9 0.29 10.7 1.3 1.1 1 0 0 1 1 1 0 IncA protein KilA-N PF04383.8 XP_011274095.1 - 0.56 9.8 3.1 1.1 8.9 2.2 1.4 1 0 0 1 1 1 0 KilA-N domain DUF3847 PF12958.2 XP_011274095.1 - 0.82 9.4 11.0 4 7.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) PEARLI-4 PF05278.7 XP_011274095.1 - 1.1 8.6 7.7 1.4 8.2 5.3 1.2 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) DUF2422 PF10337.4 XP_011274095.1 - 2.1 7.0 4.7 2.6 6.7 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) IATP PF04568.7 XP_011274095.1 - 7.4 6.6 10.9 13 5.8 7.6 1.4 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP DivIC PF04977.10 XP_011274095.1 - 8.1 6.0 9.7 2.7 7.5 4.8 1.6 2 0 0 2 2 2 0 Septum formation initiator Toxin_ToxA PF11584.3 XP_011274097.1 - 0.057 13.2 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Proteinaceous host-selective toxin ToxA PP2C PF00481.16 XP_011274099.1 - 3.7e-62 210.0 0.0 4.4e-62 209.7 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 XP_011274099.1 - 5.6e-06 25.9 0.0 9.3e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C Metallophos PF00149.23 XP_011274100.1 - 1.2e-09 37.8 2.9 2.2e-09 37.0 2.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 XP_011274100.1 - 1.2e-08 34.9 0.0 1.8e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain RNB PF00773.14 XP_011274101.1 - 1.5e-59 201.9 6.5 1.5e-59 201.9 4.5 2.5 3 0 0 3 3 3 1 RNB domain OB_RNB PF08206.6 XP_011274101.1 - 0.00032 20.1 0.1 0.26 10.8 0.0 3.0 3 0 0 3 3 3 2 Ribonuclease B OB domain Z1 PF10593.4 XP_011274102.1 - 0.027 13.7 2.4 0.041 13.1 0.5 2.1 1 1 0 1 1 1 0 Z1 domain SAC3_GANP PF03399.11 XP_011274103.1 - 7.8e-54 182.3 2.9 7.8e-54 182.3 2.0 2.6 3 0 0 3 3 3 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family SAC3 PF12209.3 XP_011274103.1 - 3.9e-10 39.7 0.3 3.9e-10 39.7 0.2 4.0 3 1 1 5 5 5 1 Leucine permease transcriptional regulator helical domain Vac7 PF12751.2 XP_011274104.1 - 7.4e-23 81.0 21.9 8.1e-16 57.8 0.3 4.0 1 1 3 5 5 5 2 Vacuolar segregation subunit 7 DUF3687 PF12459.3 XP_011274104.1 - 0.0092 15.2 1.7 0.02 14.1 1.2 1.5 1 0 0 1 1 1 1 D-Ala-teichoic acid biosynthesis protein Ribosomal_S6 PF01250.12 XP_011274105.1 - 2e-05 24.3 0.0 2.6e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S6 FAD_binding_6 PF00970.19 XP_011274106.1 - 2.3e-14 53.3 0.0 7e-14 51.7 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 XP_011274106.1 - 3.1e-14 53.4 0.0 5.1e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 XP_011274106.1 - 3.2e-05 23.8 0.9 0.00054 19.8 0.2 2.3 1 1 1 2 2 2 1 Ferric reductase NAD binding domain HTH_Mga PF08280.6 XP_011274106.1 - 0.063 13.0 2.5 6.7 6.5 0.0 3.5 3 0 0 3 3 3 0 M protein trans-acting positive regulator (MGA) HTH domain Glyoxalase PF00903.20 XP_011274107.1 - 4.3e-11 42.8 0.3 1.5e-10 41.1 0.2 1.8 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 XP_011274107.1 - 3.9e-10 40.2 0.0 5.1e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 XP_011274107.1 - 6e-06 26.2 0.0 7.5e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CppA_N PF14506.1 XP_011274107.1 - 0.0071 16.0 0.1 0.014 15.0 0.0 1.5 1 1 0 1 1 1 1 CppA N-terminal Glyoxalase_3 PF13468.1 XP_011274107.1 - 0.016 15.1 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 Glyoxalase-like domain DUF3445 PF11927.3 XP_011274108.1 - 5e-70 235.7 0.4 6.3e-70 235.3 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) DUF1348 PF07080.6 XP_011274108.1 - 0.13 12.0 2.3 0.086 12.6 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1348) COesterase PF00135.23 XP_011274109.1 - 5.1e-100 335.7 0.6 6.7e-100 335.3 0.4 1.1 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 XP_011274109.1 - 1.9e-05 23.9 0.0 3.3e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 XP_011274109.1 - 2.9e-05 23.7 0.3 0.00038 20.0 0.2 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold MFS_1 PF07690.11 XP_011274110.1 - 7.7e-32 110.3 12.5 4.2e-31 107.9 9.3 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily PepSY_TM_2 PF13703.1 XP_011274110.1 - 0.0023 18.0 0.1 0.012 15.7 0.2 2.2 2 0 0 2 2 2 1 PepSY-associated TM helix MFS_1 PF07690.11 XP_011274112.1 - 8.9e-18 64.1 18.1 1.4e-17 63.4 12.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily GDI PF00996.13 XP_011274113.1 - 1.4e-134 448.7 0.0 1.5e-134 448.5 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Pkinase PF00069.20 XP_011274114.1 - 0.00045 19.4 1.0 0.00045 19.4 0.7 1.5 2 0 0 2 2 2 1 Protein kinase domain Choline_kinase PF01633.15 XP_011274114.1 - 0.0062 16.1 1.3 0.0062 16.1 0.9 1.9 2 0 0 2 2 2 1 Choline/ethanolamine kinase RIO1 PF01163.17 XP_011274114.1 - 0.12 11.7 4.8 0.088 12.1 0.7 2.6 2 2 0 2 2 2 0 RIO1 family APH PF01636.18 XP_011274114.1 - 0.13 12.0 0.2 0.18 11.5 0.1 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family PAP2 PF01569.16 XP_011274115.1 - 4.3e-11 42.5 11.7 4.3e-11 42.5 8.1 2.7 2 1 1 3 3 3 1 PAP2 superfamily PAP2_3 PF14378.1 XP_011274115.1 - 0.025 14.1 8.5 0.062 12.8 5.9 1.6 1 1 0 1 1 1 0 PAP2 superfamily TFIIS_M PF07500.9 XP_011274116.1 - 5.8e-13 48.9 3.9 5.8e-13 48.9 2.7 2.7 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.8 XP_011274116.1 - 2e-11 44.3 0.0 6e-11 42.8 0.0 1.9 2 0 0 2 2 2 1 SPOC domain PHD PF00628.24 XP_011274116.1 - 6e-06 25.8 7.7 1.2e-05 24.8 5.3 1.6 1 0 0 1 1 1 1 PHD-finger Ribosomal_L14e PF01929.12 XP_011274117.1 - 5.6e-28 97.1 1.9 8.9e-28 96.4 1.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 XP_011274117.1 - 3e-06 26.7 0.7 5.3e-06 25.9 0.5 1.4 1 0 0 1 1 1 1 KOW motif F-actin_cap_A PF01267.12 XP_011274118.1 - 3.8e-55 186.8 2.9 4.7e-55 186.5 2.0 1.1 1 0 0 1 1 1 1 F-actin capping protein alpha subunit VHS PF00790.14 XP_011274119.1 - 5.9e-31 106.9 0.4 1.1e-30 106.0 0.3 1.4 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.23 XP_011274119.1 - 2.3e-10 39.6 0.0 4.3e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 XP_011274119.1 - 1.1e-09 37.5 0.0 2.4e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 XP_011274119.1 - 4.4e-09 35.7 0.0 7.8e-09 34.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain UIM PF02809.15 XP_011274119.1 - 0.0013 18.1 0.6 0.0013 18.1 0.4 2.2 2 0 0 2 2 2 1 Ubiquitin interaction motif TRAM_LAG1_CLN8 PF03798.11 XP_011274120.1 - 6.4e-36 123.7 22.3 6.4e-36 123.7 15.4 2.1 2 0 0 2 2 2 2 TLC domain TRAM1 PF08390.6 XP_011274120.1 - 6.7e-25 86.3 1.0 2.1e-24 84.7 0.7 1.9 1 0 0 1 1 1 1 TRAM1-like protein HIF-1 PF11413.3 XP_011274120.1 - 0.059 12.5 0.0 0.53 9.5 0.0 2.3 2 0 0 2 2 2 0 Hypoxia-inducible factor-1 Ribosomal_S2 PF00318.15 XP_011274121.1 - 5.1e-54 182.6 1.4 6.3e-54 182.3 0.0 1.9 3 0 0 3 3 3 1 Ribosomal protein S2 Mto2_bdg PF12808.2 XP_011274121.1 - 3.4 7.8 8.2 0.86 9.7 1.8 2.7 2 1 1 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Ribosomal_L10 PF00466.15 XP_011274122.1 - 1.1e-15 57.3 0.0 1.8e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 DUF3538 PF12057.3 XP_011274122.1 - 0.066 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3538) HECT PF00632.20 XP_011274123.1 - 1.3e-79 267.6 4.5 2.7e-78 263.3 0.2 3.1 3 0 0 3 3 3 2 HECT-domain (ubiquitin-transferase) Daxx PF03344.10 XP_011274123.1 - 2.7 6.3 50.6 0.017 13.6 10.2 2.1 2 0 0 2 2 2 0 Daxx Family Pkinase PF00069.20 XP_011274124.1 - 2.3e-69 233.4 0.0 5.3e-69 232.2 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011274124.1 - 1.5e-44 152.0 0.0 2.6e-44 151.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 XP_011274124.1 - 1.2e-19 70.4 0.0 1.2e-19 70.4 0.0 4.3 3 0 0 3 3 3 1 P21-Rho-binding domain Kinase-like PF14531.1 XP_011274124.1 - 1.9e-05 23.7 0.0 3.8e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 XP_011274124.1 - 0.29 10.8 0.0 1.7 8.3 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family CENP-C_C PF11699.3 XP_011274125.1 - 1.8e-23 82.3 0.6 4.6e-23 81.0 0.4 1.8 1 0 0 1 1 1 1 Mif2/CENP-C like Mif2_N PF15624.1 XP_011274125.1 - 6.3e-17 62.4 15.5 6.3e-17 62.4 10.7 5.8 1 1 2 4 4 4 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Cupin_2 PF07883.6 XP_011274125.1 - 5.7e-08 32.1 0.0 1e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Cupin domain MacB_PCD PF12704.2 XP_011274126.1 - 0.0043 16.6 0.0 0.0083 15.7 0.0 1.4 1 0 0 1 1 1 1 MacB-like periplasmic core domain ATG22 PF11700.3 XP_011274126.1 - 0.02 13.3 0.1 0.031 12.7 0.0 1.2 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like Smr PF01713.16 XP_011274127.1 - 2e-11 43.9 0.0 5.1e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 Smr domain CUE PF02845.11 XP_011274127.1 - 5.5e-09 35.3 0.1 6.9e-07 28.6 0.1 3.3 4 0 0 4 4 4 1 CUE domain UBA PF00627.26 XP_011274127.1 - 0.00018 21.2 0.0 0.2 11.5 0.0 2.9 2 0 0 2 2 2 2 UBA/TS-N domain PH PF00169.24 XP_011274130.1 - 7e-25 87.2 12.5 2.4e-12 46.9 2.5 2.3 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 XP_011274130.1 - 5.8e-11 42.6 15.7 4.1e-06 27.0 1.1 3.2 2 1 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.1 XP_011274130.1 - 2.6e-07 30.6 6.9 1.3e-06 28.3 1.0 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain Mcp5_PH PF12814.2 XP_011274130.1 - 2.9e-06 27.2 5.9 0.016 15.1 0.3 2.5 2 0 0 2 2 2 2 Meiotic cell cortex C-terminal pleckstrin homology PH_3 PF14593.1 XP_011274130.1 - 1e-05 25.3 9.2 7.4e-05 22.5 0.6 2.4 2 0 0 2 2 2 2 PH domain Myosin_TH1 PF06017.8 XP_011274130.1 - 0.015 14.6 1.7 1.5 8.1 0.1 2.5 2 1 1 3 3 3 0 Myosin tail PH_4 PF15404.1 XP_011274130.1 - 0.016 14.7 1.6 0.031 13.8 0.2 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain PH_9 PF15410.1 XP_011274130.1 - 2.5 8.2 9.1 5.8 7.0 0.2 3.2 3 2 0 3 3 3 0 Pleckstrin homology domain TPR_8 PF13181.1 XP_011274130.1 - 2.9 7.9 7.8 16 5.5 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1971 PF09313.6 XP_011274131.1 - 0.052 13.2 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1971) Apc5 PF12862.2 XP_011274131.1 - 0.062 13.1 1.7 0.3 10.9 0.3 2.6 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 5 GST_C PF00043.20 XP_011274135.1 - 2.2e-11 43.5 0.0 4.4e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 XP_011274135.1 - 9e-10 38.6 0.0 2.4e-09 37.2 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 XP_011274135.1 - 2.8e-09 36.8 0.0 1.7e-08 34.3 0.0 2.3 2 1 1 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 XP_011274135.1 - 5.1e-06 26.2 0.0 8.6e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 XP_011274135.1 - 8e-06 25.9 0.0 1.7e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 XP_011274135.1 - 6.3e-05 23.3 0.0 0.00013 22.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Ras PF00071.17 XP_011274136.1 - 6.6e-06 25.6 0.0 0.009 15.4 0.0 2.4 2 0 0 2 2 2 2 Ras family MMR_HSR1 PF01926.18 XP_011274136.1 - 0.0062 16.4 0.0 0.054 13.4 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.1 XP_011274136.1 - 0.016 15.5 0.0 0.095 13.0 0.0 2.4 1 1 0 1 1 1 0 AAA domain KTI12 PF08433.5 XP_011274136.1 - 0.035 13.2 0.2 0.32 10.1 0.0 2.2 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Miro PF08477.8 XP_011274136.1 - 0.093 13.2 0.0 0.28 11.6 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein ATP-synt_ab PF00006.20 XP_011274137.1 - 2.9e-61 206.7 0.0 3.8e-61 206.3 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 XP_011274137.1 - 1.7e-16 60.7 0.4 3.2e-16 59.7 0.3 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 XP_011274137.1 - 4.1e-13 49.3 2.0 8.4e-13 48.3 1.4 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 XP_011274137.1 - 1.9e-05 24.4 0.9 6.1e-05 22.8 0.6 1.9 1 0 0 1 1 1 1 HAS barrel domain Atg14 PF10186.4 XP_011274138.1 - 1.8e-26 92.8 17.1 2.4e-26 92.4 11.9 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 LisH PF08513.6 XP_011274138.1 - 0.1 12.4 0.8 0.33 10.8 0.5 1.9 1 0 0 1 1 1 0 LisH Sulfatase_C PF14707.1 XP_011274139.1 - 0.0081 16.4 0.4 0.0089 16.3 0.3 1.1 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF342 PF03961.8 XP_011274139.1 - 0.055 11.8 2.4 0.056 11.8 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Cbl_N PF02262.11 XP_011274139.1 - 0.12 12.1 5.6 0.23 11.1 0.1 2.1 1 1 1 2 2 2 0 CBL proto-oncogene N-terminal domain 1 Sugar_tr PF00083.19 XP_011274139.1 - 0.25 9.8 0.5 0.28 9.7 0.4 1.1 1 0 0 1 1 1 0 Sugar (and other) transporter IncA PF04156.9 XP_011274139.1 - 0.27 10.8 1.9 0.29 10.7 1.3 1.1 1 0 0 1 1 1 0 IncA protein KilA-N PF04383.8 XP_011274139.1 - 0.56 9.8 3.1 1.1 8.9 2.2 1.4 1 0 0 1 1 1 0 KilA-N domain DUF3847 PF12958.2 XP_011274139.1 - 0.82 9.4 11.0 4 7.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) PEARLI-4 PF05278.7 XP_011274139.1 - 1.1 8.6 7.7 1.4 8.2 5.3 1.2 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) DUF2422 PF10337.4 XP_011274139.1 - 2.1 7.0 4.7 2.6 6.7 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) IATP PF04568.7 XP_011274139.1 - 7.4 6.6 10.9 13 5.8 7.6 1.4 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP DivIC PF04977.10 XP_011274139.1 - 8.1 6.0 9.7 2.7 7.5 4.8 1.6 2 0 0 2 2 2 0 Septum formation initiator Sugar_tr PF00083.19 XP_011274141.1 - 1.6e-92 310.4 13.4 2e-92 310.1 9.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 XP_011274141.1 - 6e-31 107.4 44.9 1.5e-27 96.2 15.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 XP_011274141.1 - 2.8e-10 39.1 12.4 1.1e-05 24.0 1.7 2.5 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_3 PF05977.8 XP_011274141.1 - 0.00035 18.8 2.0 0.01 13.9 0.3 2.1 2 0 0 2 2 2 2 Transmembrane secretion effector Trep_Strep PF09605.5 XP_011274141.1 - 0.27 10.8 0.1 0.27 10.8 0.0 3.0 2 2 2 4 4 4 0 Hypothetical bacterial integral membrane protein (Trep_Strep) SdpI PF13630.1 XP_011274141.1 - 8.8 6.1 12.3 0.74 9.5 0.5 3.3 3 0 0 3 3 3 0 SdpI/YhfL protein family SSF PF00474.12 XP_011274142.1 - 1.4e-18 66.7 28.2 2.1e-18 66.2 19.5 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family DUF2207 PF09972.4 XP_011274142.1 - 0.054 12.0 0.1 0.054 12.0 0.1 3.8 3 1 1 4 4 4 0 Predicted membrane protein (DUF2207) E1-E2_ATPase PF00122.15 XP_011274143.1 - 1.1e-47 162.0 6.0 2.4e-47 160.8 4.2 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 XP_011274143.1 - 1.7e-23 84.1 0.0 2.5e-23 83.6 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 XP_011274143.1 - 1.3e-14 54.8 0.0 2.4e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 XP_011274143.1 - 1.7e-08 34.5 0.3 5e-08 32.9 0.2 1.9 1 0 0 1 1 1 1 Heavy-metal-associated domain Aldo_ket_red PF00248.16 XP_011274144.1 - 1.4e-63 214.3 0.1 1.6e-63 214.2 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_transf_92 PF01697.22 XP_011274144.1 - 0.053 12.8 0.0 0.082 12.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 92 T2SM PF04612.7 XP_011274145.1 - 0.026 14.3 0.0 0.042 13.6 0.0 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M NmrA PF05368.8 XP_011274146.1 - 0.00017 20.9 0.0 0.00028 20.2 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Saccharop_dh PF03435.13 XP_011274146.1 - 0.0025 16.8 0.0 0.0035 16.3 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 XP_011274146.1 - 0.0065 15.2 0.0 0.2 10.3 0.0 2.1 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 XP_011274146.1 - 0.05 13.6 0.0 0.074 13.0 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding DUF4451 PF14616.1 XP_011274147.1 - 1.6e-06 27.8 1.9 2.5e-06 27.2 0.0 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF4451) DUF3802 PF12290.3 XP_011274148.1 - 0.021 15.0 0.0 0.07 13.4 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3802) NUC173 PF08161.7 XP_011274149.1 - 0.0082 15.5 0.2 0.016 14.5 0.2 1.6 1 0 0 1 1 1 1 NUC173 domain DUF3877 PF12993.2 XP_011274150.1 - 0.0017 17.9 0.8 0.0025 17.3 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function, E. rectale Gene description (DUF3877) DAO PF01266.19 XP_011274151.1 - 3.8e-65 220.1 0.0 3.5e-64 216.9 0.0 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 XP_011274151.1 - 5.1e-06 26.4 0.3 1.2e-05 25.2 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 XP_011274151.1 - 0.00082 18.5 0.1 0.0014 17.7 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Mem_trans PF03547.13 XP_011274151.1 - 0.0046 15.3 0.2 0.016 13.5 0.2 1.8 2 0 0 2 2 2 1 Membrane transport protein Strep_67kDa_ant PF06100.6 XP_011274151.1 - 0.026 12.9 0.1 0.049 11.9 0.1 1.4 1 0 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family NAD_binding_9 PF13454.1 XP_011274151.1 - 0.031 14.0 0.2 0.068 12.9 0.1 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Saccharop_dh PF03435.13 XP_011274151.1 - 0.032 13.2 0.1 0.057 12.3 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase Trp_halogenase PF04820.9 XP_011274151.1 - 0.079 11.5 0.1 0.14 10.7 0.1 1.4 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_3 PF13738.1 XP_011274151.1 - 0.082 12.9 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 XP_011274151.1 - 0.12 12.8 0.0 0.3 11.5 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CENP-T PF15511.1 XP_011274151.1 - 0.35 10.0 11.6 0.48 9.5 8.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Ndc1_Nup PF09531.5 XP_011274151.1 - 2.5 6.4 8.6 3.2 6.0 6.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Nop14 PF04147.7 XP_011274151.1 - 4.3 5.1 19.1 5.7 4.7 13.2 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 XP_011274151.1 - 6.3 5.9 20.1 9.2 5.4 13.9 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.9 XP_011274151.1 - 6.9 4.5 14.2 9.3 4.1 9.8 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.5 XP_011274151.1 - 7.3 5.5 22.3 10 5.0 15.5 1.1 1 0 0 1 1 1 0 BUD22 Pkinase PF00069.20 XP_011274152.1 - 6.1e-67 225.4 0.1 1.1e-66 224.6 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011274152.1 - 5.9e-32 110.7 0.0 9.6e-32 110.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 XP_011274152.1 - 9.6e-08 31.3 0.0 2.9e-07 29.7 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 XP_011274152.1 - 9.5e-05 21.5 0.0 0.00018 20.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 XP_011274152.1 - 0.0047 16.3 1.0 0.011 15.1 0.7 1.5 1 1 0 1 1 1 1 RIO1 family APH PF01636.18 XP_011274152.1 - 0.025 14.3 0.0 0.04 13.6 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Sod_Fe_C PF02777.13 XP_011274153.1 - 2.4e-37 126.9 0.7 4.4e-37 126.1 0.5 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 XP_011274153.1 - 1.4e-29 102.1 2.9 2.8e-29 101.2 2.0 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain SHOCT PF09851.4 XP_011274154.1 - 0.014 14.8 0.5 0.014 14.8 0.3 3.0 3 0 0 3 3 3 0 Short C-terminal domain Phage_GPO PF05929.6 XP_011274154.1 - 0.038 13.2 2.2 0.056 12.6 1.5 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Methyltransf_4 PF02390.12 XP_011274154.1 - 0.067 12.2 2.1 0.074 12.0 0.0 2.1 2 0 0 2 2 2 0 Putative methyltransferase Ank_3 PF13606.1 XP_011274154.1 - 0.14 12.4 0.0 3.5 8.1 0.0 2.8 2 0 0 2 2 2 0 Ankyrin repeat F-box-like PF12937.2 XP_011274155.1 - 0.00017 21.2 0.1 0.0003 20.4 0.0 1.4 1 0 0 1 1 1 1 F-box-like DUF910 PF06014.6 XP_011274155.1 - 0.026 14.4 0.3 0.084 12.8 0.0 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF910) Lact_bio_phlase PF09508.5 XP_011274155.1 - 0.031 11.9 0.0 0.043 11.4 0.0 1.1 1 0 0 1 1 1 0 Lacto-N-biose phosphorylase F-box PF00646.28 XP_011274155.1 - 0.067 12.8 0.1 0.24 11.1 0.0 2.0 2 0 0 2 2 2 0 F-box domain DIM PF08194.7 XP_011274156.1 - 0.01 15.7 0.2 0.02 14.8 0.1 1.5 1 0 0 1 1 1 0 DIM protein zf-C2H2_4 PF13894.1 XP_011274157.1 - 7.7e-06 25.8 9.3 0.0028 17.8 0.3 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 XP_011274157.1 - 6e-05 23.1 11.7 0.00092 19.4 0.7 3.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 XP_011274157.1 - 0.005 17.0 10.3 0.035 14.4 0.2 3.3 3 0 0 3 3 3 2 Zinc-finger double domain Mucin PF01456.12 XP_011274157.1 - 4.4 7.0 15.9 6.9 6.4 2.5 2.5 2 0 0 2 2 2 0 Mucin-like glycoprotein TPT PF03151.11 XP_011274158.1 - 2.6e-36 124.5 11.7 2.6e-36 124.5 8.1 2.9 2 1 1 3 3 3 1 Triose-phosphate Transporter family UAA PF08449.6 XP_011274158.1 - 3.2e-19 68.9 18.3 4.3e-19 68.5 12.7 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 XP_011274158.1 - 1.3e-05 25.2 29.9 0.00011 22.2 8.7 3.1 3 1 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 XP_011274158.1 - 1 9.6 21.5 0.15 12.2 0.4 3.1 3 0 0 3 3 3 0 Multidrug resistance efflux transporter DUF1129 PF06570.6 XP_011274158.1 - 4.7 6.4 15.3 0.011 15.0 2.2 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1129) DUF3671 PF12420.3 XP_011274158.1 - 9.9 6.2 22.5 0.19 11.7 1.5 3.9 3 2 0 3 3 3 0 Protein of unknown function Asp PF00026.18 XP_011274159.1 - 3.9e-34 118.3 4.0 6.7e-34 117.5 2.8 1.4 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 XP_011274159.1 - 4.4e-06 26.7 0.1 4.4e-06 26.7 0.0 2.5 3 0 0 3 3 3 1 Xylanase inhibitor N-terminal Sec23_trunk PF04811.10 XP_011274161.1 - 1.2e-46 159.1 0.0 2.2e-46 158.2 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.7 XP_011274161.1 - 1.1e-15 57.9 0.0 2.6e-15 56.7 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.10 XP_011274161.1 - 2.6e-13 49.3 0.8 6.6e-13 47.9 0.6 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 XP_011274161.1 - 1.3e-12 47.0 5.5 2.7e-12 46.0 3.8 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 XP_011274161.1 - 0.0045 16.6 0.0 0.017 14.7 0.0 2.0 2 0 0 2 2 2 1 Gelsolin repeat XPG_N PF00752.12 XP_011274162.1 - 1.6e-25 89.2 0.0 5.5e-25 87.5 0.0 1.9 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.13 XP_011274162.1 - 2.8e-22 78.5 0.0 6.3e-22 77.4 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.2 XP_011274162.1 - 0.00011 21.7 0.0 0.00023 20.7 0.0 1.5 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.15 XP_011274162.1 - 0.00085 19.5 0.0 0.011 16.0 0.0 2.5 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_2 PF12826.2 XP_011274162.1 - 0.0048 16.7 0.0 1.9 8.4 0.0 2.5 2 0 0 2 2 2 2 Helix-hairpin-helix motif HLH PF00010.21 XP_011274163.1 - 1.4e-19 69.4 0.1 4.2e-19 67.9 0.1 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain bZIP_1 PF00170.16 XP_011274163.1 - 0.01 15.7 2.2 0.016 15.1 0.6 2.1 2 0 0 2 2 2 0 bZIP transcription factor STT3 PF02516.9 XP_011274163.1 - 0.56 9.0 2.3 0.42 9.5 0.1 1.7 2 0 0 2 2 2 0 Oligosaccharyl transferase STT3 subunit Ribosomal_L28e PF01778.12 XP_011274164.1 - 3.1e-30 104.9 3.8 3.8e-30 104.6 2.7 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family MFS_1 PF07690.11 XP_011274165.1 - 2.4e-39 135.0 17.5 3.4e-39 134.5 12.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4223 PF13978.1 XP_011274165.1 - 0.11 12.2 1.1 0.65 9.7 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4223) LRR_4 PF12799.2 XP_011274167.1 - 1.2 8.7 16.3 0.65 9.6 1.8 5.6 4 3 0 4 4 4 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 XP_011274167.1 - 8.3 6.8 7.9 40 4.7 0.5 5.6 6 1 0 6 6 6 0 Leucine Rich Repeat LRR_8 PF13855.1 XP_011274170.1 - 0.0049 16.5 27.2 0.51 10.1 0.6 8.3 5 4 4 9 9 9 4 Leucine rich repeat PRANC PF09372.5 XP_011274170.1 - 0.0084 16.0 1.4 0.0084 16.0 1.0 4.3 3 1 1 4 4 4 1 PRANC domain LRR_4 PF12799.2 XP_011274170.1 - 0.053 13.1 55.2 0.58 9.8 0.5 11.6 6 4 4 10 10 10 0 Leucine Rich repeats (2 copies) DEAD PF00270.24 XP_011274171.1 - 8e-36 123.0 0.2 1.4e-35 122.2 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 XP_011274171.1 - 6.3e-25 86.8 0.0 1.2e-24 85.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4246 PF14033.1 XP_011274171.1 - 0.003 16.2 5.1 0.0046 15.6 3.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Helicase_C_2 PF13307.1 XP_011274171.1 - 0.016 15.1 0.0 0.033 14.1 0.0 1.5 1 0 0 1 1 1 0 Helicase C-terminal domain AAA_30 PF13604.1 XP_011274171.1 - 0.037 13.6 0.0 0.082 12.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain Trypan_PARP PF05887.6 XP_011274171.1 - 0.2 11.5 11.4 0.33 10.7 7.9 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) CAP PF00188.21 XP_011274172.1 - 3.6e-18 66.2 3.2 3.6e-18 66.2 2.2 2.0 2 1 0 2 2 2 1 Cysteine-rich secretory protein family G5 PF07501.7 XP_011274172.1 - 0.0056 16.6 1.2 0.008 16.1 0.0 1.9 2 1 0 2 2 2 1 G5 domain TFIIA PF03153.8 XP_011274172.1 - 2.5 7.8 14.9 3.3 7.5 10.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CAP PF00188.21 XP_011274173.1 - 5.1e-23 81.8 3.6 1e-22 80.8 2.5 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DUF4588 PF15251.1 XP_011274173.1 - 0.079 12.9 10.4 0.11 12.4 7.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) Macoilin PF09726.4 XP_011274173.1 - 0.2 9.8 14.8 0.23 9.6 10.2 1.0 1 0 0 1 1 1 0 Transmembrane protein Dicty_REP PF05086.7 XP_011274173.1 - 0.44 8.2 9.9 0.46 8.1 6.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Apt1 PF10351.4 XP_011274173.1 - 2 7.1 10.2 2.3 6.9 7.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF572 PF04502.8 XP_011274173.1 - 2.4 7.2 7.3 3 6.9 5.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF566 PF04484.7 XP_011274173.1 - 2.6 7.4 15.3 3.3 7.1 10.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) RAP1 PF07218.6 XP_011274173.1 - 7.1 4.5 15.1 8.7 4.2 10.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF822 PF05687.8 XP_011274173.1 - 8 6.8 10.6 13 6.1 7.3 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF822) EF-hand_4 PF12763.2 XP_011274174.1 - 0.0012 18.4 0.3 0.0041 16.8 0.0 2.0 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 XP_011274174.1 - 0.043 13.1 0.0 0.1 11.9 0.0 1.7 1 0 0 1 1 1 0 EF hand DUF3808 PF10300.4 XP_011274175.1 - 2.2e-145 484.8 0.3 2.7e-145 484.5 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_11 PF13414.1 XP_011274175.1 - 0.0021 17.6 0.5 0.044 13.4 0.0 3.2 3 0 0 3 3 3 1 TPR repeat TPR_8 PF13181.1 XP_011274175.1 - 0.053 13.3 0.4 2.3 8.2 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Beta-TrCP_D PF12125.3 XP_011274175.1 - 0.061 12.9 0.1 0.15 11.6 0.1 1.6 1 0 0 1 1 1 0 D domain of beta-TrCP TPR_16 PF13432.1 XP_011274175.1 - 0.54 11.0 4.6 2.6 8.8 0.5 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 XP_011274175.1 - 1 9.4 9.8 1.5 8.9 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat IBR PF01485.16 XP_011274176.1 - 4e-16 58.6 45.1 1.1e-09 38.0 10.8 4.4 3 1 1 4 4 3 2 IBR domain zf-RING_2 PF13639.1 XP_011274176.1 - 0.00024 20.8 7.8 0.00024 20.8 5.4 4.3 3 1 1 4 4 4 1 Ring finger domain zf-C3HC4_3 PF13920.1 XP_011274176.1 - 0.00036 20.1 6.7 0.00036 20.1 4.6 4.1 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 XP_011274176.1 - 0.00042 20.2 10.7 0.00042 20.2 7.4 5.3 3 2 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 XP_011274176.1 - 0.0027 17.3 11.5 0.0027 17.3 7.9 5.4 5 1 0 5 5 5 2 Zinc finger, C3HC4 type (RING finger) ARD PF03079.9 XP_011274176.1 - 0.72 9.7 4.9 0.49 10.3 0.6 2.3 2 0 0 2 2 2 0 ARD/ARD' family Actin PF00022.14 XP_011274177.1 - 4.6e-110 367.7 0.0 7.2e-110 367.0 0.0 1.2 1 0 0 1 1 1 1 Actin DUF912 PF06024.7 XP_011274177.1 - 2.8 8.0 7.9 1.9 8.6 0.1 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) UQ_con PF00179.21 XP_011274178.1 - 2.3e-43 146.9 0.0 3e-43 146.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 XP_011274178.1 - 0.018 14.7 0.0 0.069 12.8 0.0 1.9 1 1 0 1 1 1 0 Prokaryotic E2 family B Longin PF13774.1 XP_011274179.1 - 0.015 14.8 0.1 0.02 14.4 0.0 1.2 1 0 0 1 1 1 0 Regulated-SNARE-like domain DNA_pol_B_2 PF03175.8 XP_011274179.1 - 0.023 13.3 1.3 0.027 13.1 0.9 1.1 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral Glutaredoxin PF00462.19 XP_011274180.1 - 0.034 14.1 1.6 0.36 10.8 0.0 3.5 4 0 0 4 4 4 0 Glutaredoxin KH_1 PF00013.24 XP_011274181.1 - 1.4e-70 232.8 30.7 5.2e-12 45.2 0.3 11.7 11 0 0 11 11 11 8 KH domain KH_3 PF13014.1 XP_011274181.1 - 4.9e-40 134.5 34.9 4.7e-06 26.1 0.3 12.0 14 0 0 14 14 14 7 KH domain KH_2 PF07650.12 XP_011274181.1 - 1.9e-07 30.5 20.1 1.1 8.8 0.1 8.2 8 1 1 9 9 9 5 KH domain KH_4 PF13083.1 XP_011274181.1 - 8.9e-07 28.4 11.3 0.26 10.9 0.0 7.0 8 0 0 8 8 8 2 KH domain Ras PF00071.17 XP_011274182.1 - 1.5e-58 196.7 0.3 2.3e-58 196.1 0.2 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 XP_011274182.1 - 7.7e-22 78.0 0.1 1.4e-21 77.2 0.1 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 XP_011274182.1 - 9e-17 60.8 0.1 1.2e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 XP_011274182.1 - 3.7e-08 33.0 0.0 7.6e-08 31.9 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 XP_011274182.1 - 9.3e-07 28.2 0.0 1.3e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 XP_011274182.1 - 6.5e-06 26.0 0.0 1.1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 XP_011274182.1 - 0.0033 17.4 0.4 0.018 15.0 0.3 2.0 1 1 0 1 1 1 1 AAA ATPase domain G-alpha PF00503.15 XP_011274182.1 - 0.023 13.4 0.2 0.29 9.7 0.1 2.2 1 1 0 1 1 1 0 G-protein alpha subunit AAA_22 PF13401.1 XP_011274182.1 - 0.054 13.6 0.0 1.4 9.0 0.0 2.4 1 1 1 2 2 2 0 AAA domain DUF258 PF03193.11 XP_011274182.1 - 0.064 12.4 0.1 0.18 10.9 0.0 1.7 2 1 0 2 2 2 0 Protein of unknown function, DUF258 PduV-EutP PF10662.4 XP_011274182.1 - 0.069 12.6 0.1 0.19 11.2 0.1 1.8 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Mitofilin PF09731.4 XP_011274183.1 - 7.5e-95 318.7 36.0 5.9e-80 269.5 19.5 2.1 1 1 1 2 2 2 2 Mitochondrial inner membrane protein DUF2939 PF11159.3 XP_011274183.1 - 0.3 11.3 3.7 0.43 10.7 0.2 3.0 3 1 2 5 5 5 0 Protein of unknown function (DUF2939) SSPI PF14098.1 XP_011274183.1 - 6.5 6.7 11.8 0.17 11.8 1.7 3.0 3 0 0 3 3 3 0 Small, acid-soluble spore protein I TPR_11 PF13414.1 XP_011274184.1 - 9.7e-05 21.9 0.0 0.00015 21.3 0.0 1.2 1 0 0 1 1 1 1 TPR repeat TPR_14 PF13428.1 XP_011274184.1 - 0.00071 19.9 0.1 0.85 10.4 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 XP_011274184.1 - 0.00092 19.8 0.0 0.0015 19.1 0.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 XP_011274184.1 - 0.0018 18.0 0.0 0.03 14.2 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 XP_011274184.1 - 0.0029 17.9 0.0 0.0047 17.2 0.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat YfdX PF10938.3 XP_011274184.1 - 0.008 15.8 1.1 0.25 11.0 0.1 2.1 1 1 0 2 2 2 1 YfdX protein TPR_1 PF00515.23 XP_011274184.1 - 0.023 14.2 0.0 0.13 11.8 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.9 XP_011274184.1 - 0.11 13.0 0.3 9.3 7.0 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.1 XP_011274184.1 - 0.13 12.1 0.0 0.21 11.4 0.0 1.4 1 1 0 1 1 1 0 Tetratricopeptide repeat FMO-like PF00743.14 XP_011274185.1 - 8.1e-25 86.9 1.1 8.2e-18 63.8 0.0 3.5 2 2 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 XP_011274185.1 - 1.7e-14 54.3 0.2 8.8e-11 42.2 0.1 3.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 XP_011274185.1 - 0.00063 18.7 0.0 0.041 12.7 0.0 2.5 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Bac_luciferase PF00296.15 XP_011274186.1 - 6.7e-53 179.8 0.0 9.8e-53 179.2 0.0 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase Bac_luciferase PF00296.15 XP_011274187.1 - 1.2e-50 172.3 0.0 2e-50 171.6 0.0 1.3 1 0 0 1 1 1 1 Luciferase-like monooxygenase UPF0172 PF03665.8 XP_011274188.1 - 0.0099 15.3 3.3 0.015 14.8 2.3 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) His_kinase PF06580.8 XP_011274188.1 - 0.017 15.0 2.8 7 6.6 0.1 3.0 2 1 0 3 3 3 0 Histidine kinase DUF4507 PF14964.1 XP_011274188.1 - 0.023 13.4 3.0 0.085 11.5 2.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4507) PMC2NT PF08066.7 XP_011274188.1 - 0.034 14.4 1.7 0.034 14.4 1.2 2.1 1 1 2 3 3 3 0 PMC2NT (NUC016) domain Mago_nashi PF02792.9 XP_011274188.1 - 0.057 13.1 2.1 0.078 12.6 1.5 1.3 1 0 0 1 1 1 0 Mago nashi protein Flagellin_N PF00669.15 XP_011274188.1 - 0.2 11.4 2.8 1.2 8.9 0.5 2.3 2 1 0 2 2 2 0 Bacterial flagellin N-terminal helical region TBCA PF02970.11 XP_011274188.1 - 0.21 11.6 7.6 1.8 8.6 1.9 3.0 2 1 1 3 3 3 0 Tubulin binding cofactor A DUF3323 PF11796.3 XP_011274188.1 - 0.28 10.4 1.7 6.2 6.0 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function N-terminus (DUF3323) RRF_GI PF12614.3 XP_011274188.1 - 0.32 10.8 6.7 0.48 10.2 1.0 2.8 1 1 1 3 3 3 0 Ribosome recycling factor ALMT PF11744.3 XP_011274188.1 - 0.4 9.2 3.7 0.49 8.9 2.6 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF2986 PF11661.3 XP_011274188.1 - 0.51 10.7 3.4 1.7 9.0 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2986) DUF479 PF04336.7 XP_011274188.1 - 0.53 10.4 2.9 3.7 7.7 0.7 2.7 2 1 0 2 2 2 0 Protein of unknown function, DUF479 CR6_interact PF10147.4 XP_011274188.1 - 0.64 9.2 7.0 3.1 7.0 0.5 2.3 2 1 0 2 2 2 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 DUF4164 PF13747.1 XP_011274188.1 - 0.89 9.7 5.1 2.2 8.4 0.4 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) FAM195 PF14799.1 XP_011274188.1 - 0.89 9.4 7.2 4.3 7.2 5.0 2.0 1 1 0 1 1 1 0 FAM195 family IncA PF04156.9 XP_011274188.1 - 1.1 8.8 15.7 74 2.8 10.9 2.1 1 1 0 1 1 1 0 IncA protein Colicin_Pyocin PF01320.13 XP_011274188.1 - 1.5 8.7 5.2 2.7 7.9 1.6 2.6 2 1 0 2 2 2 0 Colicin immunity protein / pyocin immunity protein AHH PF14412.1 XP_011274188.1 - 1.6 8.7 5.5 2.8 7.9 0.8 2.2 1 1 1 2 2 2 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH Baculo_PEP_C PF04513.7 XP_011274188.1 - 2 8.2 7.8 0.67 9.7 1.1 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Candida_ALS_N PF11766.3 XP_011274191.1 - 3.7e-32 111.1 1.4 7e-32 110.2 1.0 1.4 1 0 0 1 1 1 1 Cell-wall agglutinin N-terminal ligand-sugar binding AA_permease PF00324.16 XP_011274192.1 - 8.8e-130 433.2 52.1 1.1e-129 432.9 36.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 XP_011274192.1 - 8.4e-33 113.5 63.1 8.4e-33 113.5 43.7 1.8 1 1 1 2 2 2 1 Amino acid permease RhodobacterPufX PF11511.3 XP_011274192.1 - 5.4 6.4 9.3 32 4.0 0.4 3.8 3 0 0 3 3 3 0 Intrinsic membrane protein PufX Glyco_hydro_76 PF03663.9 XP_011274193.1 - 1.8e-148 494.8 12.9 2.2e-148 494.6 8.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 ChAPs PF09295.5 XP_011274194.1 - 2.5e-155 517.1 4.3 2.4e-154 513.9 0.6 2.1 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_11 PF13414.1 XP_011274194.1 - 4.5e-11 42.2 1.2 0.00025 20.6 0.1 3.0 2 1 1 3 3 3 2 TPR repeat TPR_2 PF07719.12 XP_011274194.1 - 2.8e-09 36.1 2.4 5.6e-05 22.7 0.1 4.3 5 1 1 6 6 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 XP_011274194.1 - 2.7e-07 29.9 0.0 0.067 12.9 0.0 4.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 XP_011274194.1 - 3.2e-07 29.6 0.1 0.0038 16.7 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 XP_011274194.1 - 3.3e-07 30.8 7.3 0.11 13.1 0.0 4.9 4 1 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 XP_011274194.1 - 5.7e-07 29.6 0.8 0.82 10.4 0.1 4.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 XP_011274194.1 - 0.00018 21.4 0.3 0.11 12.7 0.0 3.4 3 0 0 3 3 2 1 Tetratricopeptide repeat Apc3 PF12895.2 XP_011274194.1 - 0.00032 20.7 0.9 8.6 6.5 0.0 3.7 3 1 1 4 4 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 XP_011274194.1 - 0.00047 20.0 7.3 0.55 10.2 0.0 4.1 3 1 2 5 5 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 XP_011274194.1 - 0.0048 16.5 2.9 8.6 6.4 0.1 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 XP_011274194.1 - 0.034 14.4 10.0 0.12 12.7 0.2 4.1 3 1 2 5 5 4 0 Tetratricopeptide repeat TPR_21 PF09976.4 XP_011274194.1 - 0.051 13.5 2.0 5.8 6.8 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 XP_011274194.1 - 0.083 12.7 0.3 1.1 9.1 0.0 2.7 3 0 0 3 3 2 0 Tetratricopeptide repeat DUF1514 PF07438.6 XP_011274194.1 - 0.095 12.6 0.1 42 4.1 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1514) TPR_6 PF13174.1 XP_011274194.1 - 0.3 11.6 2.9 1.2e+02 3.4 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 XP_011274194.1 - 3 7.8 11.8 1.2 9.1 0.2 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TFIID-31kDa PF02291.10 XP_011274195.1 - 2.4e-39 134.0 0.0 3.8e-39 133.4 0.0 1.2 1 1 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Pro_isomerase PF00160.16 XP_011274196.1 - 1.9e-42 145.1 0.7 2.4e-42 144.7 0.5 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Med6 PF04934.9 XP_011274197.1 - 4.3e-55 185.0 0.6 5.6e-55 184.7 0.4 1.1 1 0 0 1 1 1 1 MED6 mediator sub complex component IGR PF09597.5 XP_011274198.1 - 2.4e-24 85.0 0.0 3.9e-24 84.3 0.0 1.4 1 0 0 1 1 1 1 IGR protein motif HIT PF01230.18 XP_011274199.1 - 1.2e-21 77.0 0.1 2.1e-21 76.2 0.1 1.4 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 XP_011274199.1 - 8.5e-06 25.9 1.9 9.2e-06 25.8 0.1 1.8 1 1 1 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding DNA_pol_alpha_N PF12254.3 XP_011274199.1 - 0.0022 17.7 2.9 0.0045 16.7 2.0 1.5 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal CwfJ_C_1 PF04677.10 XP_011274199.1 - 0.0024 17.5 0.0 0.012 15.2 0.0 1.9 1 1 1 2 2 2 1 Protein similar to CwfJ C-terminus 1 PRONE PF03759.8 XP_011274199.1 - 0.0078 14.7 0.0 0.0093 14.5 0.0 1.3 1 0 0 1 1 1 1 PRONE (Plant-specific Rop nucleotide exchanger) DUF1798 PF08807.5 XP_011274199.1 - 0.13 12.0 3.4 0.32 10.7 2.4 1.7 1 0 0 1 1 1 0 Bacterial domain of unknown function (DUF1798) AhpC-TSA PF00578.16 XP_011274200.1 - 3e-33 114.1 0.0 4.2e-33 113.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 XP_011274200.1 - 4e-16 58.8 0.0 4.7e-16 58.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 XP_011274200.1 - 4.8e-10 38.9 0.1 1.1e-09 37.8 0.1 1.6 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Rad60-SLD_2 PF13881.1 XP_011274201.1 - 2e-05 24.4 0.0 0.00011 22.0 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 XP_011274201.1 - 2.7e-05 23.4 2.6 0.00017 20.9 0.0 3.1 3 0 0 3 3 3 1 Ubiquitin family DUF2407 PF10302.4 XP_011274201.1 - 0.03 14.4 0.8 0.16 12.1 0.0 2.6 2 2 0 2 2 2 0 DUF2407 ubiquitin-like domain Fungal_trans PF04082.13 XP_011274202.1 - 1.5e-13 50.2 0.1 3.6e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 XP_011274202.1 - 2.1e-08 33.9 10.9 5.2e-08 32.6 7.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1635 PF07795.6 XP_011274202.1 - 0.053 12.8 1.0 0.11 11.8 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) ThiF PF00899.16 XP_011274203.1 - 6.3e-37 126.4 0.1 1.8e-36 124.9 0.0 1.7 2 0 0 2 2 2 1 ThiF family UBACT PF02134.16 XP_011274203.1 - 7.2e-24 83.1 0.6 1.5e-23 82.0 0.4 1.6 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 XP_011274203.1 - 6.8e-14 50.9 3.1 1.3e-13 50.0 2.1 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site MoeZ_MoeB PF05237.8 XP_011274203.1 - 0.0015 18.0 1.0 0.0051 16.3 0.0 2.2 2 1 0 2 2 2 1 MoeZ/MoeB domain Ecm33 PF12454.3 XP_011274203.1 - 0.025 14.4 1.5 0.057 13.3 1.0 1.6 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein Shikimate_DH PF01488.15 XP_011274203.1 - 0.14 12.2 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Rad52_Rad22 PF04098.10 XP_011274204.1 - 6.6e-58 194.8 0.0 1.1e-57 194.0 0.0 1.4 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein Ndc1_Nup PF09531.5 XP_011274205.1 - 7.4e-114 381.3 12.3 1e-113 380.8 8.5 1.2 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Na_H_Exchanger PF00999.16 XP_011274206.1 - 1e-71 241.5 32.2 1.2e-71 241.2 22.3 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family UPF0154 PF03672.8 XP_011274206.1 - 0.44 10.2 3.9 0.39 10.3 0.2 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) Myc_target_1 PF15179.1 XP_011274206.1 - 2.6 7.5 4.3 2.6 7.5 1.0 2.2 2 0 0 2 2 2 0 Myc target protein 1 DUF3040 PF11239.3 XP_011274206.1 - 6.2 6.9 7.3 15 5.7 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) PRRSV_2b PF07069.6 XP_011274206.1 - 6.5 7.1 11.1 0.7 10.2 0.2 3.7 3 0 0 3 3 3 0 Porcine reproductive and respiratory syndrome virus 2b Guanylate_kin PF00625.16 XP_011274207.1 - 2.1e-52 177.2 0.2 5.2e-52 175.9 0.2 1.6 1 1 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.1 XP_011274207.1 - 5.5e-05 23.0 0.0 0.00023 21.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 XP_011274207.1 - 0.0001 22.3 0.0 0.00055 19.9 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 XP_011274207.1 - 0.0016 18.7 0.1 0.011 16.0 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 XP_011274207.1 - 0.0067 17.2 0.0 0.011 16.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 XP_011274207.1 - 0.015 15.4 0.0 0.077 13.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 XP_011274207.1 - 0.02 15.0 0.3 0.15 12.2 0.2 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 XP_011274207.1 - 0.024 14.3 0.2 0.048 13.3 0.1 1.5 1 1 0 1 1 1 0 Archaeal ATPase MMR_HSR1 PF01926.18 XP_011274207.1 - 0.026 14.4 0.0 0.065 13.1 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase RNA_helicase PF00910.17 XP_011274207.1 - 0.049 13.8 0.1 0.15 12.2 0.1 2.0 2 1 0 2 2 2 0 RNA helicase ABC_tran PF00005.22 XP_011274207.1 - 0.075 13.3 0.0 0.094 13.0 0.0 1.5 1 1 0 1 1 1 0 ABC transporter Toxin_64 PF15542.1 XP_011274207.1 - 0.097 13.2 0.6 2.1 8.9 0.0 2.2 2 0 0 2 2 2 0 Putative toxin 64 KAP_NTPase PF07693.9 XP_011274207.1 - 0.16 10.8 2.3 0.77 8.6 1.6 1.8 1 1 0 1 1 1 0 KAP family P-loop domain Corona_nucleoca PF00937.13 XP_011274208.1 - 0.0013 17.7 2.4 0.0013 17.7 1.7 2.1 2 0 0 2 2 2 1 Coronavirus nucleocapsid protein RR_TM4-6 PF06459.7 XP_011274208.1 - 4.8 6.9 18.3 0.82 9.5 3.5 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 MOSC_N PF03476.11 XP_011274209.1 - 1.6e-12 47.1 0.0 2.5e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 XP_011274209.1 - 9.1e-08 31.6 0.0 1.5e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 MOSC domain TRAPP PF04051.11 XP_011274210.1 - 5.7e-40 136.3 0.0 6.9e-40 136.0 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Acetyltransf_1 PF00583.19 XP_011274211.1 - 2e-16 59.8 0.0 2.7e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 XP_011274211.1 - 6.9e-07 29.4 0.0 1e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 XP_011274211.1 - 6.4e-06 26.2 0.0 1.2e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 XP_011274211.1 - 2.9e-05 24.0 0.1 4.3e-05 23.4 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 XP_011274211.1 - 7.7e-05 22.3 0.1 0.00012 21.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 XP_011274211.1 - 0.00016 21.8 0.0 0.00024 21.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 XP_011274211.1 - 0.00031 20.6 0.0 0.00057 19.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 XP_011274211.1 - 0.0098 15.7 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.1 XP_011274211.1 - 0.028 14.3 0.1 0.039 13.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.1 XP_011274211.1 - 0.08 12.6 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Metallophos_2 PF12850.2 XP_011274212.1 - 1.8e-14 53.8 0.0 2.7e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Vfa1 PF08432.5 XP_011274212.1 - 0.039 13.9 13.5 0.052 13.5 9.3 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Tim54 PF11711.3 XP_011274212.1 - 0.069 11.7 5.9 0.089 11.3 4.1 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Zip PF02535.17 XP_011274212.1 - 0.23 10.4 0.6 0.25 10.3 0.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF1510 PF07423.6 XP_011274212.1 - 0.28 10.5 22.0 0.38 10.0 15.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Pox_Ag35 PF03286.9 XP_011274212.1 - 0.35 10.3 17.8 0.52 9.8 12.3 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SAPS PF04499.10 XP_011274212.1 - 0.48 8.9 8.0 0.61 8.6 5.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Sec62 PF03839.11 XP_011274212.1 - 0.52 9.6 8.4 0.7 9.2 5.8 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 RNA_polI_A34 PF08208.6 XP_011274212.1 - 1.3 8.6 18.6 2 8.0 12.9 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 TFIIF_alpha PF05793.7 XP_011274212.1 - 1.5 7.0 30.1 2 6.6 20.8 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RR_TM4-6 PF06459.7 XP_011274212.1 - 1.7 8.4 13.4 2.3 8.0 9.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ycf1 PF05758.7 XP_011274212.1 - 2.4 5.7 8.2 2.9 5.5 5.7 1.0 1 0 0 1 1 1 0 Ycf1 NPR3 PF03666.8 XP_011274212.1 - 3.5 6.0 10.9 4.6 5.6 7.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 GAGA_bind PF06217.7 XP_011274212.1 - 5.4 6.8 7.5 7.2 6.4 5.2 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family YqfQ PF14181.1 XP_011274212.1 - 6.6 6.7 15.4 10 6.1 10.6 1.3 1 0 0 1 1 1 0 YqfQ-like protein HIG_1_N PF04588.8 XP_011274213.1 - 2.1e-21 75.3 0.7 2.8e-21 75.0 0.5 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region SHR3_chaperone PF08229.6 XP_011274213.1 - 8 5.3 0.0 8 5.3 0.0 2.9 1 1 1 2 2 2 0 ER membrane protein SH3 Glutaredoxin PF00462.19 XP_011274215.1 - 5e-08 32.8 0.0 8.3e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_9 PF14595.1 XP_011274215.1 - 0.0051 16.3 0.2 0.0069 15.9 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 XP_011274215.1 - 0.0067 16.6 0.7 0.019 15.1 0.5 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.1 XP_011274215.1 - 0.073 12.8 0.0 0.29 10.9 0.0 1.9 1 1 0 1 1 1 0 Thioredoxin domain DDHD PF02862.12 XP_011274216.1 - 5e-52 176.9 8.5 1.2e-51 175.7 0.1 3.0 3 0 0 3 3 3 2 DDHD domain DUF676 PF05057.9 XP_011274216.1 - 0.0004 19.7 0.2 0.011 15.0 0.0 2.4 2 0 0 2 2 2 1 Putative serine esterase (DUF676) LCAT PF02450.10 XP_011274216.1 - 0.0018 17.2 0.1 0.0063 15.5 0.0 1.9 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase Lipase_3 PF01764.20 XP_011274216.1 - 0.1 12.2 0.0 0.27 10.8 0.0 1.7 1 0 0 1 1 1 0 Lipase (class 3) RNA_Me_trans PF04252.8 XP_011274217.1 - 2.9e-67 225.8 0.0 3.2e-67 225.7 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Cpn10 PF00166.16 XP_011274218.1 - 7.6e-26 89.8 0.0 8.5e-26 89.7 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit PRP3 PF08572.5 XP_011274219.1 - 5.5e-62 209.0 11.9 5.5e-62 209.0 8.3 2.2 2 0 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 XP_011274219.1 - 1.9e-34 118.1 0.5 1.9e-34 118.1 0.3 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF1115) PmbA_TldD PF01523.11 XP_011274219.1 - 0.13 11.4 2.5 0.31 10.2 1.7 1.5 1 0 0 1 1 1 0 Putative modulator of DNA gyrase HECT PF00632.20 XP_011274220.1 - 2e-94 316.2 0.5 1.3e-92 310.3 0.0 3.1 3 0 0 3 3 3 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.7 XP_011274220.1 - 1.3e-63 215.3 3.8 1.3e-63 215.3 2.6 3.6 4 0 0 4 4 4 1 Domain of Unknown Function (DUF908) DUF913 PF06025.7 XP_011274220.1 - 6.2e-54 183.2 0.0 6.2e-54 183.2 0.0 3.7 4 0 0 4 4 4 1 Domain of Unknown Function (DUF913) DUF4414 PF14377.1 XP_011274220.1 - 1.1e-15 57.4 1.2 1.1e-15 57.4 0.8 3.3 4 0 0 4 4 4 1 Domain of unknown function (DUF4414) Androgen_recep PF02166.11 XP_011274220.1 - 6.2 5.5 2.3 10 4.8 1.6 1.2 1 0 0 1 1 1 0 Androgen receptor tRNA-synt_2b PF00587.20 XP_011274221.1 - 4.4e-27 94.7 0.0 8.2e-27 93.8 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_His PF13393.1 XP_011274221.1 - 0.053 12.5 3.3 0.42 9.6 0.0 2.7 2 1 1 3 3 3 0 Histidyl-tRNA synthetase Seryl_tRNA_N PF02403.17 XP_011274221.1 - 0.1 12.6 15.8 0.019 14.9 8.1 1.9 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF1517 PF07466.6 XP_011274221.1 - 0.35 9.7 3.7 0.58 9.0 2.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Ribosomal_L27e PF01777.13 XP_011274222.1 - 3.1e-34 116.9 5.4 4.4e-34 116.4 3.8 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 XP_011274222.1 - 0.00062 19.3 0.8 0.0017 17.9 0.5 1.8 1 0 0 1 1 1 1 KOW motif DUF1512 PF07431.7 XP_011274222.1 - 0.0094 14.7 0.6 0.013 14.2 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1512) Ribosomal_L6e PF01159.14 XP_011274222.1 - 0.053 13.7 0.6 0.097 12.9 0.4 1.4 1 0 0 1 1 1 0 Ribosomal protein L6e Fe-S_assembly PF04384.8 XP_011274223.1 - 0.41 11.0 7.8 0.99 9.8 1.2 4.3 4 1 0 4 4 4 0 Iron-sulphur cluster assembly Mito_carr PF00153.22 XP_011274224.1 - 1.9e-16 59.5 0.0 0.0079 15.8 0.0 4.4 4 0 0 4 4 4 4 Mitochondrial carrier protein CDC45 PF02724.9 XP_011274224.1 - 0.0045 15.0 1.1 0.0075 14.3 0.8 1.3 1 0 0 1 1 1 1 CDC45-like protein Nucleoplasmin PF03066.10 XP_011274224.1 - 0.014 14.9 2.5 0.026 14.0 1.7 1.4 1 0 0 1 1 1 0 Nucleoplasmin Phyto_Pns9_10 PF05878.6 XP_011274224.1 - 0.088 11.8 1.9 0.14 11.1 1.3 1.2 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 Sigma70_ner PF04546.8 XP_011274224.1 - 0.14 11.7 4.6 0.27 10.8 3.2 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF4611 PF15387.1 XP_011274224.1 - 0.17 12.0 4.3 0.38 10.9 3.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) CENP-B_dimeris PF09026.5 XP_011274224.1 - 0.64 10.2 8.5 1.3 9.2 5.9 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Sporozoite_P67 PF05642.6 XP_011274224.1 - 0.94 7.2 6.1 1.7 6.4 4.2 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PBP1_TM PF14812.1 XP_011274224.1 - 1 9.7 11.4 2.1 8.6 7.9 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.1 XP_011274224.1 - 2.1 8.0 5.0 1.6 8.4 2.4 1.6 2 0 0 2 2 2 0 FAM176 family Dpy-30 PF05186.8 XP_011274225.1 - 0.00087 18.7 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 Dpy-30 motif Mif2_N PF15624.1 XP_011274225.1 - 0.47 11.0 3.9 0.62 10.6 2.7 1.2 1 0 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Syntaxin-6_N PF09177.6 XP_011274226.1 - 2.9e-13 50.0 6.1 2.9e-13 50.0 4.2 2.3 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 XP_011274226.1 - 5.8e-10 38.7 4.1 5.8e-10 38.7 2.8 3.3 3 0 0 3 3 3 1 SNARE domain FH2 PF02181.18 XP_011274226.1 - 0.003 16.5 3.4 0.003 16.5 2.4 1.7 2 0 0 2 2 2 1 Formin Homology 2 Domain Atg14 PF10186.4 XP_011274226.1 - 0.011 14.7 2.8 0.022 13.7 2.0 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF724 PF05266.9 XP_011274226.1 - 0.015 14.8 4.5 0.015 14.8 3.1 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF724) Spc7 PF08317.6 XP_011274226.1 - 0.019 13.6 10.2 0.013 14.1 3.0 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein Vps5 PF09325.5 XP_011274226.1 - 0.037 13.2 6.8 3.2 6.9 1.1 3.0 2 1 1 3 3 3 0 Vps5 C terminal like DUF4544 PF15077.1 XP_011274226.1 - 0.044 13.2 0.2 2.4 7.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4544) BLOC1_2 PF10046.4 XP_011274226.1 - 0.11 12.6 13.1 0.29 11.2 5.0 2.9 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CENP-Q PF13094.1 XP_011274226.1 - 0.13 12.2 10.5 0.88 9.5 1.7 2.2 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit F_actin_bind PF08919.5 XP_011274226.1 - 0.17 11.6 1.9 11 5.7 0.3 2.5 2 0 0 2 2 2 0 F-actin binding ACCA PF03255.9 XP_011274226.1 - 0.18 11.3 5.2 0.11 12.1 0.9 2.2 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Mnd1 PF03962.10 XP_011274226.1 - 0.19 11.3 11.2 0.016 14.8 3.7 1.9 1 1 1 2 2 2 0 Mnd1 family RRF_GI PF12614.3 XP_011274226.1 - 0.24 11.2 3.7 1.4 8.7 0.1 2.3 2 1 0 2 2 2 0 Ribosome recycling factor Sec20 PF03908.8 XP_011274226.1 - 0.33 10.6 4.6 7 6.4 1.2 2.5 2 1 0 2 2 2 0 Sec20 XH PF03469.9 XP_011274226.1 - 0.38 10.3 3.6 0.4 10.3 0.4 2.3 1 1 1 2 2 2 0 XH domain Sec8_exocyst PF04048.9 XP_011274226.1 - 0.41 10.2 6.8 0.25 10.9 3.1 1.9 2 1 0 2 2 2 0 Sec8 exocyst complex component specific domain USP8_interact PF08941.5 XP_011274226.1 - 0.57 9.4 3.2 0.98 8.7 0.6 2.2 2 0 0 2 2 2 0 USP8 interacting PCRF PF03462.13 XP_011274226.1 - 1.5 8.5 5.1 0.98 9.1 0.2 2.9 2 2 1 3 3 3 0 PCRF domain OmpH PF03938.9 XP_011274226.1 - 1.7 8.5 9.4 38 4.1 6.5 2.2 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF812 PF05667.6 XP_011274226.1 - 1.8 7.0 14.3 3 6.2 4.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Allexi_40kDa PF05549.6 XP_011274226.1 - 2.5 7.3 9.1 3.3 6.9 3.6 2.0 1 1 1 2 2 2 0 Allexivirus 40kDa protein ALMT PF11744.3 XP_011274226.1 - 2.9 6.4 8.1 1.1 7.8 3.9 1.6 1 1 0 2 2 2 0 Aluminium activated malate transporter Baculo_PEP_C PF04513.7 XP_011274226.1 - 5.2 6.8 9.3 10 5.9 3.6 2.4 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus HR1 PF02185.11 XP_011274226.1 - 5.8 6.7 12.1 0.11 12.2 0.7 3.1 3 1 1 4 4 3 0 Hr1 repeat DUF972 PF06156.8 XP_011274226.1 - 7.5 6.9 10.3 3.4 8.0 2.2 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF972) Muted PF14942.1 XP_011274226.1 - 8 6.3 13.3 1.4 8.7 3.6 2.5 1 1 2 3 3 3 0 Organelle biogenesis, Muted-like protein ADH_N PF08240.7 XP_011274227.1 - 3.3e-30 104.0 0.2 6.1e-30 103.1 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 XP_011274227.1 - 1.2e-10 41.0 0.0 1.7e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_3 PF13738.1 XP_011274227.1 - 0.043 13.8 0.0 0.064 13.2 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Transketolase_N PF00456.16 XP_011274228.1 - 1.2e-124 415.4 0.0 1.6e-124 415.0 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 XP_011274228.1 - 1.5e-42 145.1 0.0 2.9e-42 144.1 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain DXP_synthase_N PF13292.1 XP_011274228.1 - 4.3e-09 35.6 0.0 1.2e-07 30.9 0.0 2.3 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.15 XP_011274228.1 - 2.8e-05 23.0 0.0 4.4e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component Transketolase_C PF02780.15 XP_011274228.1 - 0.0032 17.3 0.0 0.017 15.0 0.0 2.2 2 1 1 3 3 3 1 Transketolase, C-terminal domain Sugar_tr PF00083.19 XP_011274229.1 - 1.7e-76 257.6 26.6 7.8e-76 255.4 18.4 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 XP_011274229.1 - 4.4e-12 45.3 58.0 1.2e-09 37.4 24.1 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 XP_011274230.1 - 5.7e-25 87.7 42.6 8.4e-25 87.2 29.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 XP_011274230.1 - 4.7e-10 38.4 37.3 2.6e-09 36.0 12.7 2.1 1 1 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.2 XP_011274230.1 - 0.01 15.6 0.1 0.01 15.6 0.0 4.7 6 1 0 6 6 6 0 MFS_1 like family TEX12 PF15219.1 XP_011274230.1 - 0.04 13.9 0.2 0.079 12.9 0.2 1.5 1 0 0 1 1 1 0 Testis-expressed 12 ETC_C1_NDUFA5 PF04716.9 XP_011274231.1 - 7.7e-20 70.1 0.1 1.4e-19 69.3 0.1 1.4 1 0 0 1 1 1 1 ETC complex I subunit conserved region Ras PF00071.17 XP_011274232.1 - 9.8e-65 216.8 0.1 1.1e-64 216.6 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 XP_011274232.1 - 7.6e-21 74.8 0.1 1.3e-20 74.0 0.0 1.4 2 0 0 2 2 1 1 Miro-like protein Arf PF00025.16 XP_011274232.1 - 4e-17 61.9 0.1 5.1e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 XP_011274232.1 - 6.6e-08 31.9 0.0 7.4e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 XP_011274232.1 - 8.1e-08 31.9 0.1 2.1e-07 30.5 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 XP_011274232.1 - 9.7e-06 25.5 0.0 1.6e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 XP_011274232.1 - 0.00013 21.2 0.0 0.00021 20.5 0.0 1.2 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 XP_011274232.1 - 0.00044 19.5 0.0 0.0028 16.9 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_22 PF13401.1 XP_011274232.1 - 0.00057 20.0 0.1 0.015 15.4 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA PF00004.24 XP_011274232.1 - 0.0059 16.7 0.0 0.14 12.3 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 XP_011274232.1 - 0.0079 15.3 0.0 0.032 13.4 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function, DUF258 G-alpha PF00503.15 XP_011274232.1 - 0.013 14.2 1.5 2.7 6.5 0.0 2.7 1 1 1 2 2 2 0 G-protein alpha subunit AAA_16 PF13191.1 XP_011274232.1 - 0.021 14.8 0.1 0.036 14.0 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 XP_011274232.1 - 0.033 13.7 0.4 0.13 11.8 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain Septin PF00735.13 XP_011274232.1 - 0.046 12.7 0.0 0.092 11.7 0.0 1.5 1 0 0 1 1 1 0 Septin MCM PF00493.18 XP_011274232.1 - 0.071 11.9 0.1 0.14 10.9 0.0 1.4 2 0 0 2 2 2 0 MCM2/3/5 family ABC_tran PF00005.22 XP_011274232.1 - 0.091 13.0 1.4 0.33 11.2 0.9 2.0 1 1 0 1 1 1 0 ABC transporter AAA_5 PF07728.9 XP_011274232.1 - 0.12 12.0 0.0 0.58 9.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) B3_4 PF03483.12 XP_011274233.1 - 6.1e-29 100.6 0.1 1.6e-28 99.3 0.1 1.7 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 XP_011274233.1 - 2.8e-19 68.6 0.1 1.3e-15 56.9 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetase B5 domain SLS PF14611.1 XP_011274233.1 - 0.011 15.1 0.4 0.03 13.7 0.2 1.7 2 0 0 2 2 2 0 Mitochondrial inner-membrane-bound regulator Herpes_V23 PF01802.12 XP_011274233.1 - 0.061 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus VP23 like capsid protein DUF726 PF05277.7 XP_011274234.1 - 2e-130 434.6 0.5 2.8e-130 434.2 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_6 PF12697.2 XP_011274234.1 - 0.05 13.4 0.0 0.097 12.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 XP_011274234.1 - 0.12 12.1 0.1 0.5 10.1 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family Ribosomal_L22e PF01776.12 XP_011274235.1 - 2.7e-42 143.3 1.6 3.1e-42 143.0 1.1 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family DUF3115 PF11312.3 XP_011274236.1 - 2.4e-97 325.6 0.3 3e-97 325.2 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3115) AICARFT_IMPCHas PF01808.13 XP_011274237.1 - 1.9e-118 395.1 0.0 2.6e-118 394.6 0.0 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 XP_011274237.1 - 1.8e-25 88.6 0.0 3.7e-25 87.6 0.0 1.6 1 0 0 1 1 1 1 MGS-like domain Ribosomal_L15e PF00827.12 XP_011274238.1 - 4.2e-85 284.1 15.5 4.9e-85 283.8 10.7 1.0 1 0 0 1 1 1 1 Ribosomal L15 Entericidin PF08085.6 XP_011274239.1 - 0.076 12.8 4.2 0.77 9.6 0.1 3.4 4 0 0 4 4 4 0 Entericidin EcnA/B family Secretin_N_2 PF07655.8 XP_011274241.1 - 1.4 9.3 14.1 1.8 9.0 9.8 1.1 1 0 0 1 1 1 0 Secretin N-terminal domain OsmC PF02566.14 XP_011274242.1 - 2.1e-05 24.6 0.0 3.5e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 OsmC-like protein Ribosomal_L10 PF00466.15 XP_011274243.1 - 3.1e-28 97.6 0.2 5.6e-28 96.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 XP_011274243.1 - 6.2e-20 71.4 5.3 1.5e-18 66.9 3.0 2.4 2 0 0 2 2 2 1 60s Acidic ribosomal protein WW PF00397.21 XP_011274244.1 - 4.9e-09 35.8 2.6 8.8e-09 35.0 1.8 1.5 1 0 0 1 1 1 1 WW domain WW PF00397.21 XP_011274245.1 - 7.2e-05 22.5 0.5 0.00018 21.2 0.4 1.7 1 0 0 1 1 1 1 WW domain Pkr1 PF08636.5 XP_011274246.1 - 2.7e-28 97.8 8.8 3.4e-28 97.5 6.1 1.1 1 0 0 1 1 1 1 ER protein Pkr1 O-antigen_lig PF13425.1 XP_011274246.1 - 0.0018 18.2 0.4 0.0021 18.0 0.3 1.1 1 0 0 1 1 1 1 O-antigen ligase like membrane protein Mem_trans PF03547.13 XP_011274246.1 - 0.015 13.6 0.2 0.019 13.2 0.1 1.2 1 0 0 1 1 1 0 Membrane transport protein DUF3260 PF11658.3 XP_011274246.1 - 0.029 12.5 0.4 0.032 12.3 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) VirB3 PF05101.8 XP_011274246.1 - 0.039 13.9 0.7 0.05 13.5 0.5 1.2 1 0 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein Herpes_LMP1 PF05297.6 XP_011274246.1 - 0.068 12.0 0.2 0.077 11.9 0.1 1.0 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) APC_CDC26 PF10471.4 XP_011274246.1 - 0.19 12.4 4.0 0.25 12.1 2.8 1.1 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 Mucin PF01456.12 XP_011274246.1 - 5.5 6.7 10.0 1.3 8.7 5.0 1.6 1 1 1 2 2 2 0 Mucin-like glycoprotein MFS_1 PF07690.11 XP_011274247.1 - 1.6e-28 99.4 15.8 1.6e-28 99.4 11.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 XP_011274247.1 - 1.3e-05 24.9 1.3 5.3e-05 22.9 0.9 2.1 1 0 0 1 1 1 1 MFS_1 like family DUF4233 PF14017.1 XP_011274247.1 - 8 6.4 9.9 0.24 11.3 0.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4233) GDA1_CD39 PF01150.12 XP_011274248.1 - 9.7e-64 215.4 4.0 2e-63 214.4 2.8 1.4 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family adh_short_C2 PF13561.1 XP_011274249.1 - 1.8e-23 83.5 0.0 2.1e-23 83.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 XP_011274249.1 - 8.1e-20 71.3 0.3 1e-19 71.0 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 XP_011274249.1 - 1.5e-10 41.0 0.1 2e-10 40.6 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 XP_011274249.1 - 0.001 18.5 0.1 0.0015 18.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF2190 PF09956.4 XP_011274249.1 - 0.031 14.0 0.1 0.24 11.1 0.0 2.3 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2190) Methyltransf_26 PF13659.1 XP_011274249.1 - 0.15 12.1 0.5 0.23 11.4 0.3 1.4 1 1 0 1 1 1 0 Methyltransferase domain CLASP_N PF12348.3 XP_011274250.1 - 1.6e-05 24.3 0.0 8.8e-05 21.9 0.0 2.1 2 0 0 2 2 2 1 CLASP N terminal HEAT PF02985.17 XP_011274250.1 - 0.0017 18.2 0.0 30 5.0 0.0 4.9 5 0 0 5 5 5 0 HEAT repeat DUF972 PF06156.8 XP_011274250.1 - 0.54 10.6 7.5 3.7 7.9 5.2 2.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) APG6 PF04111.7 XP_011274250.1 - 1.5 7.8 16.4 0.39 9.7 8.5 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF1664 PF07889.7 XP_011274250.1 - 1.7 8.4 6.1 8.3 6.2 4.2 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) TMF_DNA_bd PF12329.3 XP_011274252.1 - 0.014 15.1 1.5 0.036 13.8 1.0 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding TPD52 PF04201.10 XP_011274252.1 - 0.027 14.2 2.7 0.032 13.9 1.4 1.5 1 1 0 1 1 1 0 Tumour protein D52 family DUF1192 PF06698.6 XP_011274252.1 - 0.027 14.2 0.3 0.065 13.0 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) DivIC PF04977.10 XP_011274252.1 - 0.045 13.2 2.4 0.077 12.4 1.0 1.9 1 1 0 1 1 1 0 Septum formation initiator WD40_alt PF14077.1 XP_011274252.1 - 0.079 12.6 1.3 0.11 12.1 0.2 1.7 2 0 0 2 2 2 0 Alternative WD40 repeat motif IFP_35_N PF07334.8 XP_011274252.1 - 2.2 8.3 4.7 0.59 10.1 0.8 1.9 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus ING PF12998.2 XP_011274253.1 - 6.2e-21 74.6 0.0 6.2e-21 74.6 0.0 2.0 2 1 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 XP_011274253.1 - 1.9e-08 33.8 8.0 3.5e-08 33.0 5.5 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 XP_011274253.1 - 0.015 15.4 1.2 0.038 14.1 0.8 1.7 1 0 0 1 1 1 0 PHD-like zinc-binding domain DUF605 PF04652.11 XP_011274253.1 - 0.054 12.8 20.9 0.072 12.4 14.5 1.1 1 0 0 1 1 1 0 Vta1 like PHD_2 PF13831.1 XP_011274253.1 - 0.15 11.3 2.3 0.29 10.4 1.6 1.5 1 0 0 1 1 1 0 PHD-finger CITED PF04487.7 XP_011274253.1 - 1.4 9.1 9.9 1.9 8.6 6.8 1.2 1 0 0 1 1 1 0 CITED Macoilin PF09726.4 XP_011274253.1 - 5.6 5.1 20.5 6.8 4.8 14.2 1.1 1 0 0 1 1 1 0 Transmembrane protein Pneumo_att_G PF05539.6 XP_011274253.1 - 6.9 5.9 25.4 10 5.3 17.6 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Glyco_hydro_17 PF00332.13 XP_011274254.1 - 3.9e-05 22.8 0.0 8.1e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Glyco_hydro_53 PF07745.8 XP_011274254.1 - 0.00015 20.6 0.0 0.001 17.9 0.0 2.3 1 1 1 2 2 2 1 Glycosyl hydrolase family 53 Ras PF00071.17 XP_011274255.1 - 2.2e-58 196.2 0.2 3.1e-58 195.7 0.1 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 XP_011274255.1 - 1.6e-19 70.5 0.0 2.9e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 XP_011274255.1 - 1.6e-10 40.5 0.0 2.2e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 XP_011274255.1 - 7.8e-07 28.7 0.0 1.7e-06 27.5 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 XP_011274255.1 - 0.0017 17.6 0.1 0.0031 16.8 0.0 1.4 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.18 XP_011274255.1 - 0.0024 17.8 0.0 0.0041 17.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_25 PF13481.1 XP_011274255.1 - 0.069 12.5 0.1 0.19 11.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 XP_011274255.1 - 0.32 10.4 1.8 2 7.9 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein DAD PF02109.11 XP_011274256.1 - 1e-42 144.7 5.7 1.3e-42 144.4 3.9 1.1 1 0 0 1 1 1 1 DAD family ATP_synt_I PF03899.10 XP_011274256.1 - 0.018 15.1 2.8 0.028 14.5 2.0 1.4 1 0 0 1 1 1 0 ATP synthase I chain Innexin PF00876.13 XP_011274256.1 - 0.042 12.9 0.2 0.054 12.6 0.2 1.1 1 0 0 1 1 1 0 Innexin Herpes_UL43 PF05072.8 XP_011274256.1 - 0.073 11.8 0.0 0.095 11.4 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL43 protein DUF2207 PF09972.4 XP_011274256.1 - 0.11 11.0 1.5 0.13 10.7 1.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Y_phosphatase2 PF03162.8 XP_011274257.1 - 1.6e-40 138.1 0.0 2e-40 137.8 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Aa_trans PF01490.13 XP_011274258.1 - 5.5e-88 295.1 40.4 6.5e-88 294.9 28.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 XP_011274258.1 - 0.18 10.3 46.1 0.42 9.1 32.0 1.6 1 1 0 1 1 1 0 Amino acid permease Flocculin_t3 PF13928.1 XP_011274259.1 - 6e-24 83.9 42.8 4.1e-13 49.2 11.6 5.2 6 0 0 6 6 6 2 Flocculin type 3 repeat G-gamma PF00631.17 XP_011274259.1 - 0.12 12.0 0.1 0.36 10.6 0.0 1.8 1 0 0 1 1 1 0 GGL domain Flocculin_t3 PF13928.1 XP_011274260.1 - 1.5e-13 50.6 19.6 1.5e-13 50.6 13.6 4.9 4 1 0 4 4 4 1 Flocculin type 3 repeat Hid1 PF12722.2 XP_011274260.1 - 0.81 7.2 13.2 1.1 6.8 9.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Flocculin_t3 PF13928.1 XP_011274261.1 - 4.6e-24 84.2 71.2 4.9e-13 49.0 13.3 9.0 6 2 2 8 8 8 3 Flocculin type 3 repeat DUF693 PF05113.8 XP_011274263.1 - 0.028 13.3 1.4 0.037 12.9 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF693) Atg14 PF10186.4 XP_011274263.1 - 2.7 6.8 12.4 11 4.8 8.6 1.8 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Acetyltransf_1 PF00583.19 XP_011274264.1 - 3.7e-15 55.7 0.0 4.9e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 XP_011274264.1 - 3.1e-13 49.6 0.1 4.2e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 XP_011274264.1 - 5e-05 23.3 0.0 6.1e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 XP_011274264.1 - 0.0005 19.9 0.0 0.00057 19.7 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Hum_adeno_E3A PF05393.6 XP_011274264.1 - 0.051 13.2 0.3 9.3 5.9 0.0 2.6 2 1 1 3 3 3 0 Human adenovirus early E3A glycoprotein M_domain PF12938.2 XP_011274265.1 - 0.87 9.3 6.9 5.9 6.6 1.4 2.1 2 0 0 2 2 2 0 M domain of GW182 Cep57_CLD_2 PF14197.1 XP_011274265.1 - 1.3 9.0 15.8 0.32 10.9 1.6 3.7 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 VTC PF09359.5 XP_011274269.1 - 2e-91 305.9 0.5 2e-91 305.9 0.4 2.4 2 0 0 2 2 2 1 VTC domain SPX PF03105.14 XP_011274269.1 - 8.2e-20 71.7 27.2 2.3e-14 53.8 2.8 3.7 3 1 1 4 4 4 2 SPX domain DUF202 PF02656.10 XP_011274269.1 - 8e-10 38.8 2.3 1.9e-09 37.6 1.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF202) CPSase_L_D3 PF02787.14 XP_011274269.1 - 0.064 13.0 0.0 0.19 11.5 0.0 1.8 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain FAM176 PF14851.1 XP_011274269.1 - 2.9 7.5 10.3 5.6 6.6 4.2 2.9 3 0 0 3 3 3 0 FAM176 family Ank_2 PF12796.2 XP_011274270.1 - 6.5e-11 42.4 0.0 5.5e-08 33.0 0.0 2.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 XP_011274270.1 - 1.3e-10 40.5 0.2 3.9e-05 23.2 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 XP_011274270.1 - 2.3e-10 39.6 0.0 0.0011 19.0 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 XP_011274270.1 - 4.6e-10 39.7 0.5 0.0022 18.4 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 XP_011274270.1 - 4.6e-10 39.4 0.1 2.5e-05 24.3 0.0 2.9 2 1 0 2 2 2 2 Ankyrin repeats (many copies) KilA-N PF04383.8 XP_011274270.1 - 3.6e-05 23.3 0.1 3.6e-05 23.3 0.0 2.9 3 1 0 3 3 3 1 KilA-N domain AAA_27 PF13514.1 XP_011274270.1 - 0.17 9.5 9.8 0.67 7.5 4.4 2.1 2 0 0 2 2 2 0 AAA domain Ribosomal_S13 PF00416.17 XP_011274270.1 - 0.2 12.1 2.1 0.55 10.7 0.0 2.5 2 0 0 2 2 2 0 Ribosomal protein S13/S18 Baculo_PEP_C PF04513.7 XP_011274270.1 - 0.22 11.3 9.2 0.17 11.6 3.4 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus PhoU PF01895.14 XP_011274270.1 - 0.27 11.6 6.0 0.36 11.2 0.9 3.2 3 0 0 3 3 3 0 PhoU domain BLOC1_2 PF10046.4 XP_011274270.1 - 0.61 10.2 15.0 1 9.5 7.7 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 OmpH PF03938.9 XP_011274270.1 - 0.96 9.3 12.0 1.6 8.6 7.5 1.9 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) TMPIT PF07851.8 XP_011274270.1 - 3.9 6.4 6.8 7.3 5.5 4.7 1.3 1 0 0 1 1 1 0 TMPIT-like protein Peptidase_C48 PF02902.14 XP_011274271.1 - 1.4e-29 103.2 0.1 1.4e-29 103.2 0.1 2.2 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain SIR2 PF02146.12 XP_011274272.1 - 6.5e-55 185.6 0.0 1.1e-54 184.9 0.0 1.3 1 0 0 1 1 1 1 Sir2 family DUF3584 PF12128.3 XP_011274272.1 - 0.015 12.7 4.4 0.019 12.3 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) RNA12 PF10443.4 XP_011274274.1 - 8.4e-161 535.2 0.2 1.3e-160 534.5 0.1 1.3 1 0 0 1 1 1 1 RNA12 protein Arch_ATPase PF01637.13 XP_011274274.1 - 9.2e-07 28.7 2.6 8.6e-05 22.3 0.1 3.3 2 1 0 2 2 2 1 Archaeal ATPase RRM_1 PF00076.17 XP_011274274.1 - 5.4e-05 22.7 0.1 0.00075 19.0 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_14 PF13173.1 XP_011274274.1 - 9.5e-05 22.3 0.1 0.0014 18.5 0.0 2.9 3 0 0 3 3 3 1 AAA domain DUF2487 PF10673.4 XP_011274274.1 - 0.046 13.5 0.1 0.17 11.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2487) DUF3441 PF11923.3 XP_011274275.1 - 2.4e-31 107.6 0.0 2.4e-31 107.6 0.0 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF3441) FbpA PF05833.6 XP_011274275.1 - 3.6e-21 75.2 32.8 3.6e-21 75.2 22.7 3.4 3 1 0 3 3 3 1 Fibronectin-binding protein A N-terminus (FbpA) DUF814 PF05670.8 XP_011274275.1 - 1.4e-18 66.5 0.1 4.4e-18 64.9 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF814) Clat_adaptor_s PF01217.15 XP_011274276.1 - 9.1e-17 61.1 2.1 1.4e-16 60.4 1.5 1.3 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Glyoxalase_5 PF14696.1 XP_011274276.1 - 0.069 13.0 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal L_lactis_RepB_C PF06430.7 XP_011274276.1 - 0.08 13.0 1.4 0.12 12.4 1.0 1.3 1 0 0 1 1 1 0 Lactococcus lactis RepB C-terminus Bromo_TP PF07524.8 XP_011274277.1 - 2.7e-11 43.0 0.0 6e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 Bromodomain associated TSKS PF15358.1 XP_011274277.1 - 0.12 10.5 0.1 0.12 10.5 0.1 1.5 2 0 0 2 2 2 0 Testis-specific serine kinase substrate NUC173 PF08161.7 XP_011274278.1 - 2.9e-76 255.2 2.5 3.8e-72 241.8 0.3 3.5 3 0 0 3 3 3 2 NUC173 domain Mu-like_Pro PF10123.4 XP_011274278.1 - 0.0024 17.3 1.2 0.016 14.6 0.3 2.2 2 0 0 2 2 2 1 Mu-like prophage I protein Ribosomal_S16 PF00886.14 XP_011274279.1 - 2.6e-26 91.0 0.1 3.2e-26 90.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S16 Ras PF00071.17 XP_011274280.1 - 6.1e-42 142.7 0.1 7.6e-42 142.4 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 XP_011274280.1 - 2.5e-15 57.0 0.1 3.5e-15 56.5 0.1 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 XP_011274280.1 - 3e-07 29.8 0.0 3.7e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 XP_011274280.1 - 6.5e-07 28.9 0.1 3.2e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 XP_011274280.1 - 8.3e-05 22.5 0.0 0.00012 21.9 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_14 PF13173.1 XP_011274280.1 - 0.00024 20.9 0.1 0.00045 20.1 0.1 1.4 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.13 XP_011274280.1 - 0.00034 19.9 0.3 0.34 10.1 0.0 2.1 2 0 0 2 2 2 2 Ferrous iron transport protein B ATP_bind_1 PF03029.12 XP_011274280.1 - 0.0014 18.2 0.5 0.56 9.7 0.0 2.5 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 XP_011274280.1 - 0.0026 17.9 0.3 0.13 12.4 0.0 2.5 2 1 0 3 3 3 1 AAA domain Arch_ATPase PF01637.13 XP_011274280.1 - 0.016 14.9 1.5 0.11 12.2 1.0 2.0 1 1 0 1 1 1 0 Archaeal ATPase AAA_16 PF13191.1 XP_011274280.1 - 0.03 14.2 0.0 0.051 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Baculo_p74 PF04583.7 XP_011274280.1 - 0.033 13.3 0.3 0.047 12.8 0.2 1.2 1 0 0 1 1 1 0 Baculoviridae p74 conserved region AAA_17 PF13207.1 XP_011274280.1 - 0.035 14.9 0.3 0.35 11.7 0.2 2.3 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.1 XP_011274280.1 - 0.052 13.0 0.1 0.12 11.9 0.1 1.7 1 1 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 XP_011274280.1 - 0.067 12.3 0.1 0.13 11.4 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF258 MobB PF03205.9 XP_011274280.1 - 0.1 12.3 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Peptidase_C14 PF00656.17 XP_011274281.1 - 8.4e-13 48.5 0.1 9.1e-13 48.4 0.1 1.0 1 0 0 1 1 1 1 Caspase domain WD40 PF00400.27 XP_011274282.1 - 1.4e-37 126.2 4.1 1.4e-08 34.2 0.0 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 XP_011274282.1 - 7.2e-14 51.4 0.1 1.5e-13 50.3 0.1 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex eIF2A PF08662.6 XP_011274282.1 - 2e-05 24.4 2.7 0.0013 18.4 0.1 2.4 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 XP_011274282.1 - 0.0016 17.3 4.2 0.044 12.5 0.4 3.2 1 1 1 2 2 2 2 Nup133 N terminal like Cellulase-like PF12876.2 XP_011274282.1 - 0.021 15.2 0.4 27 5.2 0.0 3.9 4 0 0 4 4 4 0 Sugar-binding cellulase-like PHD PF00628.24 XP_011274283.1 - 3.1e-12 45.9 7.1 6.8e-12 44.8 4.9 1.6 1 0 0 1 1 1 1 PHD-finger zf-CpG_bind_C PF12269.3 XP_011274283.1 - 0.00012 21.6 0.2 0.0076 15.7 0.0 2.7 2 0 0 2 2 2 2 CpG binding protein zinc finger C terminal domain Dynamin_N PF00350.18 XP_011274284.1 - 1.6e-41 141.9 2.0 4.9e-41 140.3 0.1 2.8 3 0 0 3 3 3 1 Dynamin family Dynamin_M PF01031.15 XP_011274284.1 - 2.6e-05 23.1 3.6 0.00039 19.3 0.4 2.5 2 0 0 2 2 2 2 Dynamin central region Miro PF08477.8 XP_011274284.1 - 0.00014 22.3 0.0 0.00048 20.5 0.0 2.0 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 XP_011274284.1 - 0.00088 19.2 0.0 0.0057 16.6 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 XP_011274284.1 - 0.044 13.7 0.2 0.15 11.9 0.0 2.1 2 1 0 2 2 2 0 AAA ATPase domain Ribosomal_60s PF00428.14 XP_011274284.1 - 0.87 10.0 5.9 0.68 10.3 1.7 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein NOA36 PF06524.7 XP_011274284.1 - 3.1 6.9 4.4 5 6.2 3.1 1.2 1 0 0 1 1 1 0 NOA36 protein WD40 PF00400.27 XP_011274285.1 - 8.5e-06 25.4 7.6 0.0015 18.3 0.1 4.9 5 0 0 5 5 5 2 WD domain, G-beta repeat Me-amine-dh_L PF02975.9 XP_011274285.1 - 0.16 11.9 0.0 0.44 10.5 0.0 1.7 1 0 0 1 1 1 0 Methylamine dehydrogenase, L chain Cas_Cas6 PF01881.11 XP_011274286.1 - 7.6 6.7 9.6 12 6.1 2.8 2.9 2 1 0 2 2 2 0 CRISPR associated protein Cas6 PH_4 PF15404.1 XP_011274288.1 - 1.8e-24 86.3 0.0 6.5e-23 81.2 0.0 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 XP_011274288.1 - 2.5e-05 24.3 0.5 0.45 10.7 0.0 3.2 2 1 1 3 3 3 2 PH domain PH_6 PF15406.1 XP_011274288.1 - 0.067 13.2 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain Tnp_P_element PF12017.3 XP_011274288.1 - 0.1 11.7 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Transposase protein NAPRTase PF04095.11 XP_011274289.1 - 1.3e-60 204.7 0.0 1.7e-60 204.3 0.0 1.1 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family Nop14 PF04147.7 XP_011274290.1 - 0.17 9.7 2.3 0.19 9.5 0.2 1.9 2 0 0 2 2 2 0 Nop14-like family Y_phosphatase PF00102.22 XP_011274291.1 - 6e-63 212.3 2.1 2.5e-61 207.0 1.5 2.4 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.15 XP_011274291.1 - 5e-12 46.1 0.0 1.1e-10 41.8 0.0 2.6 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase3 PF13350.1 XP_011274291.1 - 0.00088 19.5 0.0 0.0025 18.1 0.0 1.8 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.15 XP_011274291.1 - 0.0038 16.8 0.2 0.0038 16.8 0.2 2.7 3 1 1 4 4 4 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 XP_011274291.1 - 0.065 13.2 0.0 0.63 10.0 0.0 2.5 2 0 0 2 2 2 0 Inositol hexakisphosphate YqzH PF14164.1 XP_011274291.1 - 0.066 13.1 0.7 0.25 11.2 0.5 2.0 1 0 0 1 1 1 0 YqzH-like protein DUF641 PF04859.7 XP_011274292.1 - 0.0088 15.8 6.2 0.025 14.3 4.3 1.8 1 0 0 1 1 1 1 Plant protein of unknown function (DUF641) TMF_DNA_bd PF12329.3 XP_011274292.1 - 0.011 15.4 6.0 0.011 15.4 4.2 3.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 XP_011274292.1 - 0.012 15.2 12.4 0.028 14.0 8.6 1.7 1 1 0 1 1 1 0 IncA protein CCDC155 PF14662.1 XP_011274292.1 - 0.2 11.2 18.7 0.35 10.4 8.8 3.1 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 DUF1180 PF06679.7 XP_011274292.1 - 0.32 10.8 4.9 0.076 12.9 0.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) V_ATPase_I PF01496.14 XP_011274292.1 - 0.6 7.9 8.6 1 7.1 6.0 1.5 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Tropomyosin_1 PF12718.2 XP_011274292.1 - 0.65 9.8 19.0 0.28 11.0 10.7 2.2 1 1 1 2 2 2 0 Tropomyosin like Macoilin PF09726.4 XP_011274292.1 - 1.7 6.8 30.3 3.2 5.9 21.0 1.4 1 1 0 1 1 1 0 Transmembrane protein DMPK_coil PF08826.5 XP_011274292.1 - 6.4 6.7 7.9 11 6.0 2.5 2.7 1 1 1 2 2 2 0 DMPK coiled coil domain like DivIC PF04977.10 XP_011274292.1 - 7.5 6.1 10.0 6.6 6.2 3.8 2.9 1 1 1 2 2 2 0 Septum formation initiator Ribonuclease_T2 PF00445.13 XP_011274293.1 - 8.6e-43 146.1 2.6 8.6e-43 146.1 1.8 1.9 2 0 0 2 2 2 1 Ribonuclease T2 family SprB PF13573.1 XP_011274293.1 - 2.7 7.6 7.1 6.8 6.3 0.2 3.7 3 0 0 3 3 3 0 SprB repeat Ribonuc_red_lgC PF02867.10 XP_011274294.1 - 1.4e-213 710.3 0.0 1.8e-213 710.0 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 XP_011274294.1 - 8.1e-22 76.8 0.0 1.7e-21 75.7 0.0 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 XP_011274294.1 - 4.7e-08 33.3 0.0 1.4e-07 31.8 0.0 1.9 1 0 0 1 1 1 1 ATP cone domain APG6 PF04111.7 XP_011274295.1 - 1.5e-106 356.0 10.9 1.5e-106 356.0 7.6 1.8 2 0 0 2 2 2 1 Autophagy protein Apg6 LMBR1 PF04791.11 XP_011274295.1 - 0.19 10.2 2.6 0.24 9.9 1.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF3450 PF11932.3 XP_011274295.1 - 0.26 10.5 14.0 0.14 11.4 3.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) bZIP_1 PF00170.16 XP_011274295.1 - 0.27 11.2 10.1 0.52 10.2 3.7 3.2 2 0 0 2 2 2 0 bZIP transcription factor ERM PF00769.14 XP_011274295.1 - 0.31 10.5 20.5 0.13 11.7 11.1 2.1 2 0 0 2 2 2 0 Ezrin/radixin/moesin family V_ATPase_I PF01496.14 XP_011274295.1 - 0.39 8.5 12.2 0.043 11.6 5.4 1.5 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Reo_sigmaC PF04582.7 XP_011274295.1 - 0.43 9.6 3.2 0.32 10.1 1.0 1.7 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Suppressor_APC PF11414.3 XP_011274295.1 - 1.1 9.0 13.6 0.91 9.3 5.1 3.0 2 1 1 3 3 3 0 Adenomatous polyposis coli tumour suppressor protein DUF724 PF05266.9 XP_011274295.1 - 3.7 7.1 16.5 8.6 5.9 11.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF724) ALMT PF11744.3 XP_011274295.1 - 6.8 5.2 6.6 13 4.2 4.6 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter MMR_HSR1 PF01926.18 XP_011274296.1 - 0.00012 21.9 0.0 0.00033 20.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 XP_011274296.1 - 0.021 14.2 0.1 0.28 10.6 0.0 2.5 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain Noc2 PF03715.8 XP_011274297.1 - 2e-125 417.6 7.3 2e-125 417.6 5.1 2.2 2 0 0 2 2 2 1 Noc2p family Nop14 PF04147.7 XP_011274297.1 - 0.0046 14.9 0.1 0.0046 14.9 0.0 4.2 3 1 0 3 3 3 1 Nop14-like family Mei5 PF10376.4 XP_011274298.1 - 1.4e-17 63.9 33.8 5e-16 58.8 21.6 2.3 1 1 1 2 2 2 2 Double-strand recombination repair protein NDUF_B5 PF09781.4 XP_011274298.1 - 0.99 8.6 4.4 2 7.6 3.0 1.5 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit RNA_pol_Rpb2_6 PF00562.23 XP_011274299.1 - 4.5e-122 407.5 0.9 8.6e-122 406.5 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 XP_011274299.1 - 1e-57 194.3 1.8 1.2e-57 194.0 0.4 1.7 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 XP_011274299.1 - 2.2e-41 141.3 5.2 6.1e-41 139.9 1.9 2.6 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 XP_011274299.1 - 6e-30 103.3 0.1 2e-29 101.6 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 XP_011274299.1 - 3.7e-27 93.8 0.3 5.8e-26 90.0 0.1 2.6 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 XP_011274299.1 - 8.4e-19 67.0 0.0 1.7e-18 66.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 XP_011274299.1 - 1.2e-13 50.7 0.9 2.5e-13 49.7 0.2 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 Baculo_Y142 PF04913.7 XP_011274299.1 - 0.0015 16.9 0.4 0.0015 16.9 0.3 1.5 2 0 0 2 2 2 1 Baculovirus Y142 protein Tfb2 PF03849.9 XP_011274300.1 - 4.2e-153 509.3 1.8 5.7e-153 508.8 0.2 1.7 2 0 0 2 2 2 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 XP_011274300.1 - 3e-05 23.7 0.1 6.5e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SinI PF08671.5 XP_011274300.1 - 0.07 12.5 0.0 0.23 10.9 0.0 1.9 2 0 0 2 2 2 0 Anti-repressor SinI DUF4213 PF13938.1 XP_011274300.1 - 0.13 12.4 0.0 0.4 10.8 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4213) TauD PF02668.11 XP_011274301.1 - 1.4e-49 169.1 0.1 2.1e-49 168.5 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Epimerase PF01370.16 XP_011274302.1 - 6.1e-16 58.5 0.0 9.2e-16 57.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 XP_011274302.1 - 1e-11 44.0 0.0 1.4e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 XP_011274302.1 - 2.3e-10 39.8 0.2 4.3e-09 35.6 0.1 2.0 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 XP_011274302.1 - 1.3e-08 35.1 0.2 1.6e-07 31.5 0.1 2.3 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 XP_011274302.1 - 3.1e-06 27.2 0.0 1.2e-05 25.3 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 XP_011274302.1 - 3e-05 23.0 0.2 4.6e-05 22.4 0.1 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 XP_011274302.1 - 5.9e-05 22.7 0.0 0.00014 21.6 0.0 1.6 1 0 0 1 1 1 1 KR domain DUF3479 PF11965.3 XP_011274302.1 - 0.079 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3479) Epimerase PF01370.16 XP_011274303.1 - 3.4e-17 62.6 0.0 5.1e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 XP_011274303.1 - 4.5e-13 48.5 0.0 5.9e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 XP_011274303.1 - 5.1e-09 35.4 0.2 6.4e-08 31.8 0.2 2.0 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 XP_011274303.1 - 1.4e-07 31.5 0.0 2.4e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 XP_011274303.1 - 3.3e-07 30.4 0.8 1.6e-06 28.2 0.5 2.0 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 XP_011274303.1 - 2.9e-06 27.0 0.0 5e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 XP_011274303.1 - 9.8e-06 24.6 0.1 1.6e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 XP_011274304.1 - 5e-17 62.1 0.0 8.5e-17 61.3 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 XP_011274304.1 - 7e-15 54.4 0.0 9.4e-15 54.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 XP_011274304.1 - 3.6e-12 45.7 0.2 1.5e-11 43.7 0.1 1.8 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 XP_011274304.1 - 5.8e-10 39.3 0.1 7.8e-09 35.6 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 XP_011274304.1 - 3.7e-07 29.9 0.0 8.7e-07 28.7 0.0 1.6 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 XP_011274304.1 - 5.1e-07 29.8 0.1 2.7e-06 27.5 0.1 2.0 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 XP_011274304.1 - 3.2e-05 22.9 0.2 6.4e-05 22.0 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein zf-RVT PF13966.1 XP_011274305.1 - 0.0031 17.7 0.2 0.0077 16.5 0.1 1.7 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase BATS PF06968.8 XP_011274306.1 - 1.4e-29 101.7 0.0 3.7e-29 100.4 0.0 1.8 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 XP_011274306.1 - 1.3e-19 70.9 0.2 3e-18 66.5 0.2 2.3 2 0 0 2 2 2 1 Radical SAM superfamily DUF3161 PF11362.3 XP_011274306.1 - 0.016 15.1 0.6 0.28 11.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3161) GCR1_C PF12550.3 XP_011274307.1 - 0.00017 21.4 1.3 0.00041 20.1 0.9 1.6 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Med15 PF09606.5 XP_011274307.1 - 0.079 11.1 60.6 0.11 10.6 42.0 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 XP_011274307.1 - 0.4 8.8 51.8 0.67 8.1 35.9 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Zip PF02535.17 XP_011274307.1 - 1.8 7.5 18.2 3.2 6.6 12.6 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter KIAA1328 PF15369.1 XP_011274307.1 - 2 8.1 33.4 0.95 9.2 19.7 2.1 2 0 0 2 2 2 0 Uncharacterised protein KIAA1328 ADH_N PF08240.7 XP_011274308.1 - 3.3e-30 104.0 2.6 3.3e-30 104.0 1.8 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 XP_011274308.1 - 7.6e-21 74.0 0.1 1.4e-20 73.1 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 XP_011274308.1 - 0.0007 20.1 0.0 0.0017 18.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain ThiF PF00899.16 XP_011274308.1 - 0.00082 19.2 0.3 0.0016 18.2 0.2 1.5 1 0 0 1 1 1 1 ThiF family ADH_N_assoc PF13823.1 XP_011274308.1 - 0.0009 18.8 0.0 0.002 17.7 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated TrkA_N PF02254.13 XP_011274308.1 - 0.0029 17.5 0.3 0.0055 16.6 0.2 1.5 1 0 0 1 1 1 1 TrkA-N domain GFO_IDH_MocA PF01408.17 XP_011274308.1 - 0.0043 17.5 0.1 0.0078 16.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold 3HCDH_N PF02737.13 XP_011274308.1 - 0.0066 16.1 0.5 0.01 15.5 0.3 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 XP_011274308.1 - 0.016 14.1 0.3 0.021 13.8 0.2 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase F420_oxidored PF03807.12 XP_011274308.1 - 0.019 15.3 0.5 0.038 14.4 0.3 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 XP_011274308.1 - 0.022 14.8 0.2 0.12 12.4 0.1 2.0 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ABC_tran PF00005.22 XP_011274308.1 - 0.024 14.9 0.0 0.044 14.0 0.0 1.5 1 0 0 1 1 1 0 ABC transporter 2-Hacid_dh_C PF02826.14 XP_011274308.1 - 0.047 12.8 0.0 0.076 12.1 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 XP_011274309.1 - 5.1e-13 49.5 0.0 1.7e-08 34.7 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 XP_011274309.1 - 3.8e-07 30.2 0.0 0.005 16.7 0.0 2.8 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 XP_011274309.1 - 2e-06 26.9 0.0 6.1e-05 22.1 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 XP_011274309.1 - 0.00026 20.1 1.8 0.068 12.2 0.0 2.4 2 0 0 2 2 2 2 FAD binding domain NAD_binding_9 PF13454.1 XP_011274309.1 - 0.00033 20.4 0.1 0.059 13.1 0.0 3.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 XP_011274309.1 - 0.0015 17.5 2.6 2.5 6.9 0.1 3.9 4 0 0 4 4 4 1 FAD dependent oxidoreductase Shikimate_DH PF01488.15 XP_011274309.1 - 0.0017 18.4 0.0 0.15 12.1 0.1 2.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.12 XP_011274309.1 - 0.045 12.8 0.2 1.1 8.2 0.0 2.8 3 0 0 3 3 3 0 Thi4 family Pyr_redox PF00070.22 XP_011274309.1 - 0.045 14.1 2.3 5.8 7.4 0.1 3.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 XP_011274309.1 - 0.086 12.8 2.2 0.85 9.6 0.1 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DUF2639 PF11121.3 XP_011274309.1 - 0.14 11.7 1.8 0.24 10.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2639) ThiF PF00899.16 XP_011274309.1 - 0.14 11.9 0.5 5.1 6.9 0.1 3.1 3 0 0 3 3 3 0 ThiF family AA_permease PF00324.16 XP_011274310.1 - 1.9e-134 448.6 52.9 2.3e-134 448.3 36.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 XP_011274310.1 - 1.4e-33 116.1 61.6 1.5e-33 116.0 42.2 1.4 1 1 0 1 1 1 1 Amino acid permease Peptidase_M50 PF02163.17 XP_011274310.1 - 0.061 12.2 2.4 9.9 5.0 1.9 3.2 2 1 0 2 2 2 0 Peptidase family M50 TMEM125 PF15109.1 XP_011274310.1 - 0.085 12.9 0.2 0.36 10.9 0.1 2.1 1 0 0 1 1 1 0 TMEM125 protein family RhodobacterPufX PF11511.3 XP_011274310.1 - 0.68 9.3 11.9 0.045 13.1 1.1 3.5 3 0 0 3 3 3 0 Intrinsic membrane protein PufX Synaptobrevin PF00957.16 XP_011274310.1 - 2.9 7.5 6.1 40 3.9 1.2 3.5 3 0 0 3 3 3 0 Synaptobrevin AA_permease PF00324.16 XP_011274311.1 - 3.2e-126 421.4 48.1 3.9e-126 421.2 33.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 XP_011274311.1 - 5.5e-30 104.2 46.1 5.5e-30 104.2 32.0 2.0 1 1 0 2 2 2 1 Amino acid permease Ribosomal_L19e PF01280.15 XP_011274312.1 - 1.1e-55 187.4 8.5 1.1e-55 187.4 5.9 1.8 1 1 1 2 2 2 1 Ribosomal protein L19e Sec62 PF03839.11 XP_011274312.1 - 0.0094 15.3 1.4 5.2 6.4 0.0 2.1 2 0 0 2 2 2 2 Translocation protein Sec62 zf-C2H2_4 PF13894.1 XP_011274313.1 - 0.00011 22.3 3.8 0.00011 22.3 2.6 3.7 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.21 XP_011274313.1 - 0.00045 20.4 6.6 0.00045 20.4 4.6 4.3 4 1 0 4 4 4 1 Zinc finger, C2H2 type zf-met PF12874.2 XP_011274313.1 - 0.0046 17.1 4.5 0.11 12.7 1.7 2.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 XP_011274313.1 - 0.0064 16.1 1.5 0.0064 16.1 1.1 2.1 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.1 XP_011274313.1 - 0.015 15.5 1.2 0.015 15.5 0.9 3.5 3 1 0 3 3 3 0 Zinc-finger double domain zf-C2H2_jaz PF12171.3 XP_011274313.1 - 0.075 13.2 8.9 0.26 11.5 3.2 3.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-FCS PF06467.9 XP_011274313.1 - 0.16 11.6 6.7 1.3 8.7 0.5 3.0 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif zf-C2H2_2 PF12756.2 XP_011274313.1 - 0.25 11.4 10.4 0.043 13.9 1.4 3.2 1 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) BIR PF00653.16 XP_011274313.1 - 0.91 9.9 5.5 1.4 9.3 0.4 2.7 2 1 0 2 2 2 0 Inhibitor of Apoptosis domain zf-Di19 PF05605.7 XP_011274313.1 - 3.3 7.9 11.0 1.1 9.3 4.7 2.5 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding RGS PF00615.14 XP_011274315.1 - 7.5e-12 45.3 0.5 6.1e-10 39.2 0.1 2.5 2 0 0 2 2 2 2 Regulator of G protein signaling domain Svf1 PF08622.5 XP_011274317.1 - 9.3e-123 409.3 7.6 1.4e-122 408.7 5.3 1.3 1 0 0 1 1 1 1 Svf1-like DUF2683 PF10884.3 XP_011274317.1 - 0.0017 18.2 0.0 0.0047 16.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2683) Kei1 PF08552.6 XP_011274318.1 - 4e-36 124.4 11.3 4.4e-30 104.7 2.5 2.1 1 1 1 2 2 2 2 Inositolphosphorylceramide synthase subunit Kei1 DUF973 PF06157.6 XP_011274318.1 - 9.7e-05 21.4 4.4 0.00012 21.1 3.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF973) RIO1 PF01163.17 XP_011274319.1 - 5.3e-71 237.8 2.2 5.3e-71 237.8 1.5 1.8 2 0 0 2 2 2 1 RIO1 family Pkinase PF00069.20 XP_011274319.1 - 7.3e-08 31.8 0.1 7.3e-08 31.8 0.1 2.5 4 0 0 4 4 4 1 Protein kinase domain APH PF01636.18 XP_011274319.1 - 0.048 13.3 0.1 2.6 7.6 0.0 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family CDC45 PF02724.9 XP_011274319.1 - 0.55 8.1 31.3 0.026 12.5 15.2 2.2 2 0 0 2 2 2 0 CDC45-like protein SDA1 PF05285.7 XP_011274319.1 - 7.5 5.7 43.0 0.65 9.2 22.3 2.3 2 0 0 2 2 2 0 SDA1 TLD PF07534.11 XP_011274320.1 - 2.1e-30 105.5 1.4 9.9e-29 100.1 1.0 2.6 1 1 0 1 1 1 1 TLD EF-hand_1 PF00036.27 XP_011274320.1 - 0.023 13.9 0.1 0.16 11.3 0.0 2.6 2 0 0 2 2 2 0 EF hand NUC153 PF08159.7 XP_011274321.1 - 7.8e-14 50.9 0.9 7.8e-14 50.9 0.6 3.7 3 0 0 3 3 3 2 NUC153 domain SET PF00856.23 XP_011274322.1 - 0.0062 16.8 0.0 0.012 15.8 0.0 1.7 1 0 0 1 1 1 1 SET domain COPR5 PF15340.1 XP_011274322.1 - 0.078 13.3 1.4 0.2 12.0 1.0 1.6 1 0 0 1 1 1 0 Cooperator of PRMT5 family SOBP PF15279.1 XP_011274323.1 - 0.098 13.0 20.0 0.16 12.3 13.8 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein DUF2413 PF10310.4 XP_011274323.1 - 0.4 9.4 28.4 0.66 8.7 19.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF605 PF04652.11 XP_011274323.1 - 0.83 8.9 33.2 1.2 8.4 23.0 1.2 1 0 0 1 1 1 0 Vta1 like FAM196 PF15265.1 XP_011274323.1 - 1.1 8.4 30.8 1.4 8.0 21.3 1.1 1 0 0 1 1 1 0 FAM196 family Asp-B-Hydro_N PF05279.6 XP_011274323.1 - 1.4 8.7 20.6 1.9 8.2 14.3 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region MIP-T3 PF10243.4 XP_011274323.1 - 2.9 6.2 33.4 4 5.8 23.1 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Hid1 PF12722.2 XP_011274323.1 - 3.7 5.1 26.3 4.6 4.8 18.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TFIIA PF03153.8 XP_011274323.1 - 4.4 7.1 29.3 6.9 6.4 20.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SelP_N PF04592.9 XP_011274323.1 - 6.7 6.0 12.6 11 5.3 8.8 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region PAT1 PF09770.4 XP_011274323.1 - 6.9 4.7 25.3 9.3 4.3 17.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1510 PF07423.6 XP_011274323.1 - 7.7 5.8 32.5 13 5.0 22.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Daxx PF03344.10 XP_011274323.1 - 8.1 4.8 28.7 11 4.4 19.9 1.1 1 0 0 1 1 1 0 Daxx Family Bud13 PF09736.4 XP_011274323.1 - 8.6 6.6 16.3 16 5.7 11.3 1.4 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Ycf1 PF05758.7 XP_011274323.1 - 8.7 3.9 16.5 11 3.5 11.4 1.1 1 0 0 1 1 1 0 Ycf1 EMP24_GP25L PF01105.19 XP_011274324.1 - 2.7e-32 111.9 2.0 3.4e-32 111.6 1.4 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD BBS2_C PF14782.1 XP_011274324.1 - 0.049 12.1 2.1 0.28 9.7 0.0 1.9 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, C-terminal TSC22 PF01166.13 XP_011274324.1 - 0.075 13.0 1.2 0.12 12.3 0.8 1.3 1 0 0 1 1 1 0 TSC-22/dip/bun family ThiF PF00899.16 XP_011274325.1 - 3.7e-42 143.3 0.0 6.1e-42 142.6 0.0 1.3 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 XP_011274325.1 - 5.1e-24 83.6 0.1 8.7e-24 82.9 0.0 1.4 1 0 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 XP_011274325.1 - 1.1e-11 45.0 0.0 2.3e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.15 XP_011274325.1 - 0.00034 20.7 0.1 0.003 17.6 0.1 2.5 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Herpes_BLRF2 PF05812.7 XP_011274325.1 - 0.0016 18.2 0.5 0.0029 17.3 0.3 1.4 1 0 0 1 1 1 1 Herpesvirus BLRF2 protein WD40 PF00400.27 XP_011274326.1 - 0.0023 17.7 1.0 2 8.4 0.0 4.5 5 0 0 5 5 5 1 WD domain, G-beta repeat YL1 PF05764.8 XP_011274326.1 - 1 8.9 7.0 1.6 8.2 4.9 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Cys_Met_Meta_PP PF01053.15 XP_011274327.1 - 2e-62 210.7 0.0 6.8e-62 208.9 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 XP_011274327.1 - 0.00037 19.3 0.0 0.00058 18.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V GDC-P PF02347.11 XP_011274327.1 - 0.012 14.3 0.0 0.016 13.9 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein Rad60-SLD PF11976.3 XP_011274328.1 - 1.1e-18 66.6 2.3 1.1e-18 66.6 1.6 3.7 4 0 0 4 4 4 1 Ubiquitin-2 like Rad60 SUMO-like ATP-synt_S1 PF05827.7 XP_011274329.1 - 1.2e-39 136.3 0.0 1.4e-39 136.1 0.0 1.0 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) SNARE PF05739.14 XP_011274330.1 - 4.3e-20 71.1 2.0 9.5e-20 70.0 0.5 2.3 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.1 XP_011274330.1 - 8e-10 38.6 9.3 8e-10 38.6 6.4 2.6 2 1 0 2 2 2 1 Syntaxin-like protein BMFP PF04380.8 XP_011274330.1 - 0.0051 16.9 2.6 0.017 15.2 0.7 2.8 3 1 0 3 3 3 1 Membrane fusogenic activity MCPsignal PF00015.16 XP_011274330.1 - 0.0086 15.6 1.0 0.0086 15.6 0.7 2.3 1 1 1 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Synaptobrevin PF00957.16 XP_011274330.1 - 0.025 14.1 0.5 0.053 13.1 0.0 1.8 2 0 0 2 2 2 0 Synaptobrevin Blo-t-5 PF11642.3 XP_011274330.1 - 0.059 13.1 11.0 0.31 10.8 1.0 3.1 2 2 1 3 3 3 0 Mite allergen Blo t 5 AAA_13 PF13166.1 XP_011274330.1 - 0.067 11.6 15.3 0.41 9.0 1.0 2.0 2 0 0 2 2 2 0 AAA domain DDE_Tnp_1_assoc PF13808.1 XP_011274330.1 - 0.1 12.2 0.3 0.35 10.5 0.1 1.9 2 0 0 2 2 2 0 DDE_Tnp_1-associated Streptin-Immun PF11083.3 XP_011274330.1 - 0.17 11.8 8.5 0.35 10.8 0.3 3.1 3 0 0 3 3 3 0 Lantibiotic streptin immunity protein Syntaxin PF00804.20 XP_011274330.1 - 0.28 11.3 13.7 72 3.6 9.5 2.8 1 1 0 1 1 1 0 Syntaxin zf-C4H2 PF10146.4 XP_011274330.1 - 5.1 7.0 7.6 0.83 9.6 1.0 2.2 2 1 0 2 2 2 0 Zinc finger-containing protein DUF4014 PF13198.1 XP_011274330.1 - 5.8 7.3 6.4 0.5 10.8 0.3 2.3 4 0 0 4 4 3 0 Protein of unknown function (DUF4014) DUF1664 PF07889.7 XP_011274330.1 - 6.7 6.5 8.2 1.2 8.9 0.5 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) WD40 PF00400.27 XP_011274331.1 - 1.5e-52 173.6 25.6 4.1e-11 42.3 0.4 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat SH3_9 PF14604.1 XP_011274331.1 - 0.012 15.1 3.0 0.016 14.8 0.2 2.6 2 0 0 2 2 2 0 Variant SH3 domain Coatomer_WDAD PF04053.9 XP_011274331.1 - 0.017 13.9 6.4 0.77 8.4 1.4 3.3 2 2 0 2 2 2 0 Coatomer WD associated region Fusion_gly_K PF01621.12 XP_011274331.1 - 0.019 14.0 0.5 0.029 13.4 0.3 1.2 1 0 0 1 1 1 0 Cell fusion glycoprotein K FAD_binding_6 PF00970.19 XP_011274332.1 - 3.6e-05 23.8 0.0 0.00012 22.1 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 XP_011274332.1 - 9.3e-05 22.9 0.0 0.35 11.4 0.0 2.6 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 XP_011274332.1 - 0.014 15.3 0.3 0.31 10.9 0.2 2.3 1 1 0 1 1 1 0 Ferric reductase NAD binding domain Velvet PF11754.3 XP_011274333.1 - 5.7e-55 186.0 0.6 3.1e-54 183.6 0.4 1.9 1 1 0 1 1 1 1 Velvet factor RNB PF00773.14 XP_011274334.1 - 7.2e-64 216.1 0.2 7.2e-64 216.1 0.2 1.8 2 0 0 2 2 2 1 RNB domain tRNA-synt_1b PF00579.20 XP_011274335.1 - 3.3e-69 233.2 0.3 6.5e-69 232.2 0.1 1.5 1 1 1 2 2 2 1 tRNA synthetases class I (W and Y) Securin PF04856.8 XP_011274335.1 - 0.00067 19.4 0.4 0.00085 19.0 0.3 1.3 1 0 0 1 1 1 1 Securin sister-chromatid separation inhibitor ICL PF00463.16 XP_011274335.1 - 0.096 10.8 1.3 0.14 10.3 0.9 1.1 1 0 0 1 1 1 0 Isocitrate lyase family Hira PF07569.6 XP_011274336.1 - 1.4e-80 269.5 0.0 3.6e-80 268.2 0.0 1.7 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.27 XP_011274336.1 - 6e-11 41.7 1.5 0.00056 19.6 0.0 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat HIRA_B PF09453.5 XP_011274336.1 - 1.5e-08 33.9 1.8 3.9e-08 32.6 1.2 1.8 1 0 0 1 1 1 1 HIRA B motif CK_II_beta PF01214.13 XP_011274337.1 - 6.1e-71 237.7 0.0 7.5e-71 237.4 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit EIIC-GAT PF03611.9 XP_011274338.1 - 0.062 12.0 1.2 0.093 11.4 0.9 1.1 1 0 0 1 1 1 0 PTS system sugar-specific permease component TBX PF12598.3 XP_011274338.1 - 0.24 11.7 4.0 11 6.4 0.0 2.2 1 1 1 2 2 2 0 T-box transcription factor Response_reg PF00072.19 XP_011274339.1 - 4.9e-26 90.9 0.2 9e-26 90.0 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 XP_011274339.1 - 9.1e-26 89.7 4.2 3.4e-25 87.9 2.9 2.0 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 XP_011274339.1 - 4.5e-12 45.7 0.2 1.4e-11 44.2 0.1 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.20 XP_011274339.1 - 6.1e-05 23.1 10.2 0.00079 19.5 0.1 3.3 4 0 0 4 4 4 2 HAMP domain GTPase_Cys_C PF12631.2 XP_011274339.1 - 0.075 13.4 0.0 0.43 11.0 0.0 2.3 2 0 0 2 2 2 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE ubiquitin PF00240.18 XP_011274340.1 - 3.6e-32 109.5 0.5 4.9e-32 109.1 0.4 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 XP_011274340.1 - 8.8e-31 105.2 10.9 1.4e-30 104.6 7.6 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 XP_011274340.1 - 1.5e-15 56.5 0.7 2.3e-15 56.0 0.1 1.5 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 XP_011274340.1 - 9.9e-06 25.7 0.1 4e-05 23.7 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.4 XP_011274340.1 - 0.013 15.6 0.1 0.014 15.5 0.1 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 XP_011274340.1 - 0.013 15.3 0.0 0.026 14.4 0.0 1.5 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Telomere_Sde2 PF13019.1 XP_011274340.1 - 0.018 14.7 0.0 0.029 14.0 0.0 1.2 1 0 0 1 1 1 0 Telomere stability and silencing Fer2_3 PF13085.1 XP_011274340.1 - 0.11 12.3 1.5 0.46 10.3 1.0 2.0 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain DUF2870 PF11069.3 XP_011274340.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) TPR_MLP1_2 PF07926.7 XP_011274341.1 - 8.2e-24 83.8 24.9 8.2e-24 83.8 17.3 16.4 3 3 9 13 13 13 5 TPR/MLP1/MLP2-like protein zf-primase PF09329.6 XP_011274342.1 - 3.2e-13 49.0 0.9 6.3e-13 48.1 0.6 1.5 1 0 0 1 1 1 1 Primase zinc finger MRP-L51 PF10244.4 XP_011274342.1 - 0.17 11.9 0.0 0.17 11.9 0.0 2.8 3 0 0 3 3 3 0 Mitochondrial ribosomal subunit PspB PF06667.7 XP_011274342.1 - 1.1 9.2 3.8 3.2 7.7 0.9 2.9 3 0 0 3 3 3 0 Phage shock protein B DAGK_cat PF00781.19 XP_011274343.1 - 9.8e-10 37.9 0.0 3.1e-09 36.3 0.0 1.8 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain DUF3212 PF11486.3 XP_011274343.1 - 0.078 12.7 0.9 0.35 10.6 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3212) NYD-SP28_assoc PF14775.1 XP_011274344.1 - 0.034 13.8 0.0 0.066 12.9 0.0 1.5 1 0 0 1 1 1 0 Sperm tail C-terminal domain DUF4208 PF13907.1 XP_011274344.1 - 0.041 14.0 0.1 0.11 12.7 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4208) Pcc1 PF09341.5 XP_011274345.1 - 3.2e-19 68.7 0.2 4.1e-19 68.3 0.1 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 PIN_4 PF13638.1 XP_011274346.1 - 1.7e-16 60.5 2.2 7.1e-16 58.5 0.2 2.8 2 0 0 2 2 2 1 PIN domain HSF_DNA-bind PF00447.12 XP_011274348.1 - 1.1e-38 131.5 1.0 3.2e-38 130.0 0.7 1.8 1 0 0 1 1 1 1 HSF-type DNA-binding Actin PF00022.14 XP_011274349.1 - 1.4e-24 86.2 0.0 1.3e-18 66.5 0.0 2.6 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.8 XP_011274349.1 - 5.2e-09 35.1 0.0 6.3e-07 28.2 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein SMN PF06003.7 XP_011274350.1 - 0.052 12.6 4.1 0.058 12.4 2.8 1.0 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) U1snRNP70_N PF12220.3 XP_011274350.1 - 0.11 12.8 2.3 0.13 12.6 1.6 1.1 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RabGAP-TBC PF00566.13 XP_011274350.1 - 0.83 9.0 3.2 1.1 8.7 2.2 1.1 1 0 0 1 1 1 0 Rab-GTPase-TBC domain Ligase_CoA PF00549.14 XP_011274351.1 - 5.6e-25 87.7 0.1 1e-24 86.8 0.0 1.4 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.14 XP_011274351.1 - 1.3e-24 86.5 3.2 1e-23 83.6 0.9 2.3 2 0 0 2 2 2 1 CoA binding domain Succ_CoA_lig PF13607.1 XP_011274351.1 - 1e-07 31.6 0.0 2e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 XP_011274351.1 - 1.6e-05 25.0 0.1 0.00016 21.7 0.0 2.5 3 0 0 3 3 3 1 CoA binding domain KH_1 PF00013.24 XP_011274352.1 - 0.00022 20.7 0.7 0.00059 19.4 0.5 1.7 1 0 0 1 1 1 1 KH domain MDM31_MDM32 PF08118.6 XP_011274353.1 - 2.4e-89 300.1 17.5 5.7e-43 147.1 1.2 3.0 1 1 2 3 3 3 3 Yeast mitochondrial distribution and morphology (MDM) proteins DDRGK PF09756.4 XP_011274353.1 - 0.068 12.5 0.6 0.13 11.6 0.4 1.4 1 0 0 1 1 1 0 DDRGK domain NAD_binding_10 PF13460.1 XP_011274354.1 - 3.4e-12 46.7 0.0 6.1e-12 45.9 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding HIM1 PF08732.5 XP_011274354.1 - 2.7e-08 32.7 0.0 1.4e-07 30.3 0.0 1.8 1 1 0 1 1 1 1 HIM1 Epimerase PF01370.16 XP_011274354.1 - 1.6e-05 24.4 0.0 0.0022 17.4 0.0 2.5 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family NmrA PF05368.8 XP_011274354.1 - 0.00032 20.0 0.0 0.0011 18.2 0.0 1.9 1 1 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 XP_011274354.1 - 0.00087 18.2 0.0 0.16 10.8 0.0 2.2 2 0 0 2 2 2 2 RmlD substrate binding domain Mannosyl_trans3 PF11051.3 XP_011274355.1 - 5.7e-82 275.0 0.0 8.5e-82 274.5 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Glyco_transf_8 PF01501.15 XP_011274355.1 - 0.0051 16.1 0.1 0.011 15.1 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 8 ABC_tran PF00005.22 XP_011274356.1 - 3.5e-47 160.1 5.4 2.5e-23 82.9 0.0 3.6 3 1 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 XP_011274356.1 - 1.1e-20 74.7 21.4 7.8e-10 39.1 0.5 5.3 4 2 0 5 5 5 3 AAA domain ABC_tran_2 PF12848.2 XP_011274356.1 - 1.4e-19 69.7 6.9 1.4e-19 69.7 4.8 3.1 3 0 0 3 3 2 1 ABC transporter SMC_N PF02463.14 XP_011274356.1 - 1e-12 47.7 0.8 0.00016 20.9 0.3 4.1 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 XP_011274356.1 - 7.2e-09 36.5 5.9 0.00036 21.3 0.1 3.8 4 0 0 4 4 4 2 AAA domain Miro PF08477.8 XP_011274356.1 - 1.9e-07 31.5 0.7 0.073 13.5 0.6 3.7 2 1 0 2 2 2 2 Miro-like protein AAA_16 PF13191.1 XP_011274356.1 - 2.5e-07 30.8 0.1 0.0087 16.0 0.0 3.0 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 XP_011274356.1 - 1.5e-06 27.5 0.0 0.034 13.3 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 XP_011274356.1 - 2.4e-06 27.4 0.0 0.11 12.4 0.0 3.1 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.1 XP_011274356.1 - 3.2e-06 26.5 4.6 0.026 14.0 0.0 3.0 3 0 0 3 3 2 2 P-loop containing region of AAA domain NACHT PF05729.7 XP_011274356.1 - 3.5e-06 26.7 0.1 0.018 14.6 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_28 PF13521.1 XP_011274356.1 - 6e-06 26.3 1.0 0.15 11.9 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 XP_011274356.1 - 1.3e-05 25.3 0.0 0.19 11.8 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_14 PF13173.1 XP_011274356.1 - 2.4e-05 24.2 0.0 0.45 10.4 0.0 3.4 3 1 0 3 3 2 2 AAA domain AAA_25 PF13481.1 XP_011274356.1 - 9.2e-05 21.9 0.0 0.57 9.5 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.1 XP_011274356.1 - 9.7e-05 22.6 13.4 0.086 13.1 0.0 4.8 5 2 0 5 5 4 2 AAA domain MobB PF03205.9 XP_011274356.1 - 0.0001 22.0 0.4 0.57 9.8 0.0 3.2 3 0 0 3 3 3 2 Molybdopterin guanine dinucleotide synthesis protein B G-alpha PF00503.15 XP_011274356.1 - 0.00011 21.0 1.9 0.17 10.5 0.0 2.6 1 1 0 2 2 2 2 G-protein alpha subunit RNA_helicase PF00910.17 XP_011274356.1 - 0.00012 22.1 0.0 0.34 11.1 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_10 PF12846.2 XP_011274356.1 - 0.00016 21.1 0.1 1.3 8.3 0.0 3.4 3 1 0 3 3 3 2 AAA-like domain AAA PF00004.24 XP_011274356.1 - 0.00019 21.6 0.0 0.63 10.2 0.0 3.6 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 XP_011274356.1 - 0.0002 20.3 0.1 0.39 9.5 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF815) NB-ARC PF00931.17 XP_011274356.1 - 0.00036 19.5 0.0 0.67 8.7 0.0 2.6 2 0 0 2 2 2 2 NB-ARC domain AAA_33 PF13671.1 XP_011274356.1 - 0.00042 20.1 0.1 0.35 10.7 0.0 2.9 2 1 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 XP_011274356.1 - 0.00043 20.1 0.5 0.00043 20.1 0.3 3.8 3 2 1 4 4 4 1 Dynamin family SbcCD_C PF13558.1 XP_011274356.1 - 0.00044 20.1 0.1 1.7 8.6 0.0 3.2 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.9 XP_011274356.1 - 0.0005 19.8 0.2 0.79 9.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) PduV-EutP PF10662.4 XP_011274356.1 - 0.00053 19.4 0.2 1.2 8.5 0.0 2.9 3 0 0 3 3 2 2 Ethanolamine utilisation - propanediol utilisation ArgK PF03308.11 XP_011274356.1 - 0.0018 17.1 0.4 0.25 10.0 0.0 3.0 3 0 0 3 3 3 1 ArgK protein AAA_23 PF13476.1 XP_011274356.1 - 0.0019 18.5 35.5 0.18 12.1 0.0 5.3 5 0 0 5 5 5 2 AAA domain ATP-synt_ab PF00006.20 XP_011274356.1 - 0.0019 17.7 0.0 0.26 10.7 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_15 PF13175.1 XP_011274356.1 - 0.0028 16.7 34.1 0.032 13.2 0.1 6.0 2 1 2 5 5 4 2 AAA ATPase domain NTPase_1 PF03266.10 XP_011274356.1 - 0.008 15.9 0.0 3.7 7.2 0.0 2.7 2 0 0 2 2 2 1 NTPase FeoB_N PF02421.13 XP_011274356.1 - 0.018 14.2 0.0 7.1 5.8 0.0 2.7 2 0 0 2 2 2 0 Ferrous iron transport protein B VirE PF05272.6 XP_011274356.1 - 0.027 13.9 0.1 3.3 7.1 0.0 2.5 2 0 0 2 2 2 0 Virulence-associated protein E Ras PF00071.17 XP_011274356.1 - 0.038 13.3 1.9 5.1 6.4 0.0 3.1 3 0 0 3 3 3 0 Ras family Viral_helicase1 PF01443.13 XP_011274356.1 - 0.055 12.9 0.0 1.3 8.4 0.0 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF87 PF01935.12 XP_011274356.1 - 0.6 9.8 0.0 0.6 9.8 0.0 4.6 5 1 0 5 5 3 0 Domain of unknown function DUF87 COX6B PF02297.12 XP_011274357.1 - 2e-23 82.2 7.8 2.3e-23 81.9 5.4 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb NusA_N PF08529.6 XP_011274357.1 - 0.069 13.1 0.3 0.084 12.8 0.2 1.1 1 0 0 1 1 1 0 NusA N-terminal domain Prolamin_like PF05617.6 XP_011274357.1 - 0.076 13.1 2.4 0.13 12.3 1.5 1.6 1 1 1 2 2 2 0 Prolamin-like Bac_rhodopsin PF01036.13 XP_011274358.1 - 5.1e-55 186.1 9.9 6.3e-55 185.8 6.9 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Mob_synth_C PF06463.8 XP_011274359.1 - 8.9e-38 128.8 0.0 1.5e-37 128.1 0.0 1.4 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 XP_011274359.1 - 4.2e-30 105.1 0.0 9.3e-30 103.9 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 XP_011274359.1 - 8.7e-10 38.8 0.0 2e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 XP_011274359.1 - 2.2e-07 30.9 0.0 9.4e-07 28.8 0.0 2.0 2 0 0 2 2 2 1 4Fe-4S single cluster domain Herpes_UL21 PF03252.8 XP_011274359.1 - 0.076 11.4 0.0 0.11 10.8 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL21 Imm25 PF15571.1 XP_011274359.1 - 0.28 11.3 3.1 0.51 10.4 0.2 2.6 3 0 0 3 3 3 0 Immunity protein 25 MoaC PF01967.16 XP_011274360.1 - 4.3e-51 172.1 2.5 5.2e-51 171.8 1.7 1.1 1 0 0 1 1 1 1 MoaC family TAA-Trp-ring PF15401.1 XP_011274361.1 - 0.13 12.4 1.3 0.32 11.2 0.6 2.1 1 1 0 1 1 1 0 Tryptophan-ring motif of head of Trimeric autotransporter adhesin MCM PF00493.18 XP_011274363.1 - 2.8e-138 460.2 2.6 4.6e-138 459.5 1.8 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 XP_011274363.1 - 5.2e-22 78.5 37.0 5.2e-22 78.5 25.6 3.3 4 0 0 4 4 4 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 XP_011274363.1 - 4.5e-14 52.9 1.2 7.5e-14 52.2 0.0 2.0 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 XP_011274363.1 - 2.1e-08 33.5 0.0 2.3e-06 26.9 0.0 2.5 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 XP_011274363.1 - 2.3e-07 30.6 0.0 5.1e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 XP_011274363.1 - 9.5e-05 21.9 0.1 0.00022 20.7 0.1 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 XP_011274363.1 - 0.00061 19.4 0.1 0.0042 16.6 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 XP_011274363.1 - 0.035 14.2 0.1 0.092 12.9 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ApoO PF09769.4 XP_011274363.1 - 0.14 11.8 0.4 0.3 10.7 0.2 1.5 1 0 0 1 1 1 0 Apolipoprotein O PAP2 PF01569.16 XP_011274364.1 - 9.6e-21 73.8 1.2 9.6e-21 73.8 0.8 1.7 2 1 0 2 2 2 1 PAP2 superfamily DUF1705 PF08019.7 XP_011274364.1 - 0.027 13.9 3.7 3.1 7.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1705) YibE_F PF07907.6 XP_011274364.1 - 0.37 9.9 3.4 0.97 8.5 0.0 2.2 2 0 0 2 2 2 0 YibE/F-like protein Polysacc_synt PF01943.12 XP_011274364.1 - 0.65 9.2 7.8 0.82 8.8 0.1 2.5 2 1 0 2 2 2 0 Polysaccharide biosynthesis protein ABC2_membrane_4 PF12730.2 XP_011274364.1 - 1.1 8.3 10.8 3.4 6.7 4.3 2.5 2 1 0 2 2 2 0 ABC-2 family transporter protein PSP1 PF04468.7 XP_011274365.1 - 4.1e-26 90.7 1.2 9.7e-26 89.5 0.8 1.7 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Cys_Met_Meta_PP PF01053.15 XP_011274366.1 - 6.5e-62 209.0 0.0 1.6e-61 207.7 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 XP_011274366.1 - 0.00067 18.5 0.0 0.001 17.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Ssl1 PF04056.9 XP_011274367.1 - 1.4e-83 279.2 0.4 1.9e-83 278.7 0.3 1.2 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.7 XP_011274367.1 - 1.6e-21 76.0 11.4 1.6e-21 76.0 7.9 2.7 3 0 0 3 3 3 1 TFIIH C1-like domain VWA_2 PF13519.1 XP_011274367.1 - 1.8e-11 44.4 0.0 2.5e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain DZR PF12773.2 XP_011274367.1 - 0.82 9.5 22.5 2.6 7.9 5.2 3.4 2 1 0 2 2 2 0 Double zinc ribbon ADH_zinc_N PF00107.21 XP_011274368.1 - 3.5e-29 100.9 0.0 5.6e-29 100.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 XP_011274368.1 - 1.3e-09 38.9 0.0 2.9e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 XP_011274368.1 - 1.8e-08 34.0 0.0 3e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 XP_011274368.1 - 0.027 14.4 0.1 0.04 13.9 0.1 1.3 1 0 0 1 1 1 0 NADH(P)-binding Methyltransf_11 PF08241.7 XP_011274368.1 - 0.038 14.4 0.0 3.5 8.1 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_18 PF12847.2 XP_011274368.1 - 0.04 14.4 0.0 1.3 9.6 0.0 2.3 1 1 1 2 2 2 0 Methyltransferase domain adh_short PF00106.20 XP_011274368.1 - 0.061 13.2 0.0 0.091 12.6 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Rad60-SLD PF11976.3 XP_011274369.1 - 1e-18 66.7 0.1 1.4e-18 66.3 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 XP_011274369.1 - 3.5e-09 35.9 0.0 4.6e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family SRP9-21 PF05486.7 XP_011274369.1 - 0.099 12.3 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle 9 kDa protein (SRP9) Pkinase PF00069.20 XP_011274370.1 - 1.4e-72 244.0 0.0 2.9e-72 242.9 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011274370.1 - 1.4e-37 129.1 0.0 2.8e-37 128.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 XP_011274370.1 - 0.00088 18.3 0.0 0.0023 16.9 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 XP_011274370.1 - 0.017 14.8 0.1 0.055 13.1 0.1 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family zf-BED PF02892.10 XP_011274371.1 - 0.00015 21.4 0.0 0.00025 20.7 0.0 1.4 1 0 0 1 1 1 1 BED zinc finger FHA PF00498.21 XP_011274372.1 - 0.00011 22.2 0.0 0.00045 20.2 0.0 2.2 1 0 0 1 1 1 1 FHA domain LCD1 PF09798.4 XP_011274373.1 - 1e-62 212.1 35.0 2e-62 211.1 24.3 1.4 1 1 0 1 1 1 1 DNA damage checkpoint protein DivIC PF04977.10 XP_011274373.1 - 0.42 10.1 9.1 1.3 8.5 3.1 2.6 1 1 1 2 2 2 0 Septum formation initiator DUF2360 PF10152.4 XP_011274373.1 - 1.3 9.2 11.0 0.34 11.1 4.5 2.2 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) MCPVI PF02993.9 XP_011274373.1 - 1.8 8.6 8.4 1.1 9.3 4.1 1.7 2 0 0 2 2 2 0 Minor capsid protein VI IncA PF04156.9 XP_011274373.1 - 1.8 8.1 8.9 0.18 11.3 2.8 1.8 2 0 0 2 2 2 0 IncA protein EMG1 PF03587.9 XP_011274374.1 - 1.5e-78 262.7 0.0 1.8e-78 262.5 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase DUF948 PF06103.6 XP_011274375.1 - 0.0057 16.4 9.9 2.7 7.9 0.8 4.4 4 1 0 4 4 4 3 Bacterial protein of unknown function (DUF948) OAD_gamma PF04277.8 XP_011274375.1 - 1.1 9.6 4.7 14 6.1 0.0 3.3 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain Ninjurin PF04923.7 XP_011274375.1 - 4.1 7.1 10.7 0.054 13.2 0.5 2.8 3 0 0 3 3 3 0 Ninjurin MRC1 PF09444.5 XP_011274377.1 - 1e-30 106.9 20.9 1e-30 106.9 14.5 10.4 6 4 4 10 10 10 1 MRC1-like domain Peptidase_M1 PF01433.15 XP_011274378.1 - 6.9e-09 35.2 0.7 0.00076 18.6 0.0 3.4 3 0 0 3 3 3 3 Peptidase family M1 PI3_PI4_kinase PF00454.22 XP_011274379.1 - 3e-29 102.1 0.0 6.8e-29 100.9 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.3 XP_011274379.1 - 1e-15 57.2 3.4 1.2e-15 56.9 0.2 2.8 3 0 0 3 3 3 1 Yeast phosphatidylinositol-4-OH kinase Pik1 PI3Ka PF00613.15 XP_011274379.1 - 0.00019 20.7 0.3 0.00047 19.3 0.2 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.1 XP_011274379.1 - 0.02 13.9 0.0 0.043 12.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) KH_1 PF00013.24 XP_011274380.1 - 0.016 14.8 0.0 0.034 13.8 0.0 1.5 1 0 0 1 1 1 0 KH domain KH_3 PF13014.1 XP_011274380.1 - 0.079 12.6 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 KH domain CT47 PF15623.1 XP_011274380.1 - 1.4 8.6 15.8 1.9 8.1 10.9 1.2 1 0 0 1 1 1 0 Cancer/testis gene family 47 SLX9 PF15341.1 XP_011274381.1 - 1.7 9.0 12.0 2.1 8.7 8.3 1.1 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 DUF2031 PF09592.5 XP_011274381.1 - 2.8 7.0 11.1 3.4 6.7 7.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) AA_permease_2 PF13520.1 XP_011274382.1 - 3.5e-51 174.0 50.8 4.4e-51 173.7 35.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 XP_011274382.1 - 2.7e-25 88.6 40.0 3.2e-25 88.4 27.7 1.0 1 0 0 1 1 1 1 Amino acid permease SKG6 PF08693.5 XP_011274383.1 - 1.7e-05 24.0 0.2 3.3e-05 23.0 0.1 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain SH3_1 PF00018.23 XP_011274383.1 - 6e-05 22.3 0.2 0.00015 21.0 0.0 1.7 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 XP_011274383.1 - 0.001 18.5 0.0 0.002 17.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Rifin_STEVOR PF02009.11 XP_011274383.1 - 0.0013 18.4 1.3 0.0028 17.3 0.1 2.0 2 0 0 2 2 2 1 Rifin/stevor family SH3_2 PF07653.12 XP_011274383.1 - 0.0022 17.4 0.0 0.004 16.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF4448 PF14610.1 XP_011274383.1 - 0.0023 17.4 0.6 0.0055 16.2 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) TMEM154 PF15102.1 XP_011274383.1 - 0.0078 15.9 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 TMEM154 protein family DUF3611 PF12263.3 XP_011274383.1 - 0.017 14.5 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) Rax2 PF12768.2 XP_011274383.1 - 0.023 13.9 0.0 0.042 13.0 0.0 1.4 1 0 0 1 1 1 0 Cortical protein marker for cell polarity EphA2_TM PF14575.1 XP_011274383.1 - 0.027 14.8 0.9 0.084 13.2 0.0 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain IncA PF04156.9 XP_011274383.1 - 0.16 11.5 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 IncA protein She9_MDM33 PF05546.6 XP_011274384.1 - 1.3e-88 295.9 13.0 1.3e-88 295.9 9.0 1.9 2 0 0 2 2 2 1 She9 / Mdm33 family Phi-29_GP16_7 PF06720.6 XP_011274384.1 - 3.8e-05 23.3 1.2 3.8e-05 23.3 0.8 2.3 3 0 0 3 3 3 1 Bacteriophage phi-29 early protein GP16.7 PsbH PF00737.15 XP_011274384.1 - 0.0023 17.4 0.2 0.005 16.3 0.1 1.5 1 0 0 1 1 1 1 Photosystem II 10 kDa phosphoprotein DUF948 PF06103.6 XP_011274384.1 - 5.6 6.9 10.3 2.1 8.2 0.5 3.6 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) HlyD PF00529.15 XP_011274384.1 - 9.8 5.3 9.8 0.27 10.5 2.4 1.5 2 0 0 2 2 2 0 HlyD family secretion protein G-patch_2 PF12656.2 XP_011274385.1 - 5.9e-24 83.7 1.5 5.9e-24 83.7 1.1 2.4 3 0 0 3 3 3 1 DExH-box splicing factor binding site G-patch PF01585.18 XP_011274385.1 - 0.068 12.9 0.2 0.068 12.9 0.1 2.0 2 0 0 2 2 2 0 G-patch domain Ribosomal_L28 PF00830.14 XP_011274385.1 - 0.086 12.6 0.4 0.086 12.6 0.3 2.0 2 0 0 2 2 2 0 Ribosomal L28 family MCR_alpha PF02249.12 XP_011274385.1 - 0.12 12.3 0.1 0.26 11.3 0.1 1.4 1 0 0 1 1 1 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain Glyco_transf_22 PF03901.12 XP_011274386.1 - 3.7e-51 174.4 26.7 5.1e-51 173.9 18.5 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family IBN_N PF03810.14 XP_011274387.1 - 1.4e-14 53.7 1.3 3e-14 52.6 0.1 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain Cse1 PF08506.5 XP_011274387.1 - 6.5e-06 24.9 0.4 6.5e-06 24.9 0.3 2.5 3 0 0 3 3 3 1 Cse1 Vac14_Fab1_bd PF12755.2 XP_011274387.1 - 0.2 12.0 1.7 15 6.0 0.0 4.0 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region CBFD_NFYB_HMF PF00808.18 XP_011274388.1 - 8.4e-13 48.1 0.7 1.2e-12 47.6 0.5 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 XP_011274388.1 - 0.023 14.8 0.0 0.033 14.3 0.0 1.2 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Utp12 PF04003.7 XP_011274389.1 - 9.5e-24 83.4 1.9 1.7e-23 82.6 1.3 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Rsc14 PF08586.5 XP_011274389.1 - 0.87 10.1 6.4 2.9 8.4 0.2 3.4 3 0 0 3 3 3 0 RSC complex, Rsc14/Ldb7 subunit Peptidase_M18 PF02127.10 XP_011274390.1 - 6.5e-171 568.5 0.0 8.3e-171 568.2 0.0 1.1 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 XP_011274390.1 - 2.6e-08 33.0 0.0 5.2e-06 25.4 0.0 2.2 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase Peptidase_M20 PF01546.23 XP_011274390.1 - 0.014 14.9 0.0 0.037 13.5 0.0 1.3 1 1 0 1 1 1 0 Peptidase family M20/M25/M40 Pribosyltran PF00156.22 XP_011274391.1 - 4.7e-09 36.0 0.0 7.4e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DUF768 PF05589.6 XP_011274391.1 - 0.1 12.5 0.1 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF768) MFS_1 PF07690.11 XP_011274392.1 - 7.8e-18 64.3 45.0 2.4e-09 36.3 10.7 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Tmemb_40 PF10160.4 XP_011274392.1 - 0.0011 18.2 0.8 0.0011 18.2 0.6 1.9 3 0 0 3 3 3 1 Predicted membrane protein KilA-N PF04383.8 XP_011274392.1 - 0.17 11.5 0.2 1.7 8.3 0.0 2.2 2 0 0 2 2 2 0 KilA-N domain dsrm PF00035.20 XP_011274393.1 - 0.0027 18.2 0.0 1.2 9.8 0.0 2.7 2 0 0 2 2 2 2 Double-stranded RNA binding motif Glyco_hydro_28 PF00295.12 XP_011274394.1 - 0.04 12.8 0.3 0.055 12.4 0.2 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 28 DUF2852 PF11014.3 XP_011274395.1 - 0.018 14.9 4.1 0.018 14.9 2.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) Nitr_red_alph_N PF14710.1 XP_011274395.1 - 0.026 14.7 0.8 0.093 12.9 0.0 2.4 2 0 0 2 2 2 0 Respiratory nitrate reductase alpha N-terminal DUF2852 PF11014.3 XP_011274396.1 - 0.019 14.9 0.2 0.042 13.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) DUF2852 PF11014.3 XP_011274398.1 - 9.4e-07 28.7 6.0 0.0092 15.9 0.4 2.9 2 0 0 2 2 2 2 Protein of unknown function (DUF2852) DUF3813 PF12758.2 XP_011274398.1 - 0.019 15.0 1.8 2.1 8.5 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3813) IU_nuc_hydro PF01156.14 XP_011274399.1 - 1.5e-75 254.2 0.0 1.7e-75 254.1 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase SurE PF01975.12 XP_011274400.1 - 7.5e-43 146.1 0.0 1e-42 145.6 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE GAF_2 PF13185.1 XP_011274401.1 - 4e-08 33.8 0.0 8.1e-08 32.8 0.0 1.3 1 1 0 1 1 1 1 GAF domain GAF_3 PF13492.1 XP_011274401.1 - 0.00082 19.4 0.0 0.0014 18.7 0.0 1.5 1 1 0 1 1 1 1 GAF domain GAF PF01590.21 XP_011274401.1 - 0.009 16.1 0.0 0.01 15.9 0.0 1.2 1 0 0 1 1 1 1 GAF domain DIT1_PvcA PF05141.7 XP_011274402.1 - 1.5e-100 336.0 0.0 2.1e-100 335.6 0.0 1.2 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein S1 PF00575.18 XP_011274403.1 - 1.6e-13 50.5 0.0 2.6e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 S1 RNA binding domain SHS2_Rpb7-N PF03876.12 XP_011274403.1 - 3.6e-12 46.2 0.0 5.8e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RNA_pol_Rbc25 PF08292.7 XP_011274403.1 - 0.0022 18.1 0.0 0.0031 17.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 Ribosomal_L13 PF00572.13 XP_011274404.1 - 1.5e-43 147.8 0.3 1.9e-43 147.5 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 RNA_pol_Rpb2_6 PF00562.23 XP_011274405.1 - 1.3e-125 419.1 0.1 2.3e-125 418.3 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 XP_011274405.1 - 8.4e-68 227.2 0.1 1.4e-67 226.5 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 XP_011274405.1 - 1.7e-49 167.8 0.0 3.4e-49 166.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 XP_011274405.1 - 4.3e-30 103.8 0.1 9.4e-30 102.7 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 XP_011274405.1 - 1.3e-26 92.1 0.4 2.9e-26 91.0 0.3 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 XP_011274405.1 - 8.1e-22 76.7 0.1 1.8e-21 75.6 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 XP_011274405.1 - 1.4e-20 72.9 0.2 4.2e-20 71.4 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Ribosomal_L23 PF00276.15 XP_011274406.1 - 6e-22 77.3 0.0 1.3e-21 76.3 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L23 TB2_DP1_HVA22 PF03134.14 XP_011274407.1 - 9.9e-20 70.0 9.6 1.3e-19 69.7 6.0 1.7 2 0 0 2 2 2 1 TB2/DP1, HVA22 family DUF3446 PF11928.3 XP_011274407.1 - 2.4 8.4 10.3 8.4 6.6 2.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3446) Fungal_trans PF04082.13 XP_011274408.1 - 5e-16 58.3 0.5 9e-16 57.5 0.3 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 XP_011274408.1 - 3.2e-09 36.5 12.0 3.2e-09 36.5 8.3 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 XP_011274409.1 - 6.4e-81 272.2 26.6 7.3e-81 272.0 18.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 XP_011274409.1 - 6.1e-32 110.6 54.0 5.6e-24 84.5 20.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 XP_011274409.1 - 5.2e-06 25.1 1.3 5.2e-06 25.1 0.9 3.4 3 1 1 4 4 4 2 MFS/sugar transport protein CN_hydrolase PF00795.17 XP_011274410.1 - 1.3e-28 99.6 0.0 1.7e-28 99.2 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Peptidase_C14 PF00656.17 XP_011274412.1 - 0.027 14.1 2.1 0.048 13.3 1.5 1.3 1 1 0 1 1 1 0 Caspase domain Sugar_tr PF00083.19 XP_011274413.1 - 1.4e-81 274.4 26.3 1.6e-81 274.2 18.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 XP_011274413.1 - 1.2e-31 109.7 53.4 1.6e-23 83.0 21.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 XP_011274413.1 - 3.8e-06 25.5 1.8 3.8e-06 25.5 1.2 3.5 3 1 1 4 4 4 2 MFS/sugar transport protein TRI12 PF06609.8 XP_011274413.1 - 0.28 9.3 14.5 0.13 10.4 2.2 2.5 3 0 0 3 3 3 0 Fungal trichothecene efflux pump (TRI12) CN_hydrolase PF00795.17 XP_011274414.1 - 2.1e-29 102.2 0.0 2.6e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase EutQ PF06249.7 XP_011274417.1 - 0.00049 19.6 0.0 0.0006 19.3 0.0 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.7 XP_011274417.1 - 0.0025 17.1 0.0 0.0033 16.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Pirin PF02678.11 XP_011274417.1 - 0.032 14.1 0.0 0.035 13.9 0.0 1.1 1 0 0 1 1 1 0 Pirin Fer4_14 PF13394.1 XP_011274417.1 - 0.044 13.8 0.0 0.052 13.5 0.0 1.1 1 0 0 1 1 1 0 4Fe-4S single cluster domain Cupin_6 PF12852.2 XP_011274417.1 - 0.095 12.3 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Cupin Cupin_2 PF07883.6 XP_011274417.1 - 0.14 11.6 0.4 0.28 10.7 0.3 1.6 1 1 0 1 1 1 0 Cupin domain ISN1 PF06437.6 XP_011274419.1 - 3.3e-152 506.9 0.0 3.6e-152 506.8 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase Ribosomal_S4e PF00900.15 XP_011274420.1 - 2.4e-32 110.3 0.4 3.3e-31 106.7 0.2 2.1 2 0 0 2 2 2 1 Ribosomal family S4e S4 PF01479.20 XP_011274420.1 - 9.7e-08 31.3 0.1 2e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 S4 domain RS4NT PF08071.7 XP_011274420.1 - 1e-07 31.6 0.1 2.3e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain KOW PF00467.24 XP_011274420.1 - 4.2e-05 23.0 1.6 4.2e-05 23.0 1.1 3.1 4 0 0 4 4 4 1 KOW motif CIA30 PF08547.7 XP_011274421.1 - 3.1e-42 144.1 0.0 3.7e-42 143.8 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Choline_transpo PF04515.7 XP_011274422.1 - 1.9e-96 322.6 18.3 1.9e-96 322.6 12.7 2.2 1 1 0 2 2 2 2 Plasma-membrane choline transporter DUF872 PF05915.7 XP_011274422.1 - 2.6 7.9 6.2 1 9.2 0.0 2.9 2 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) Xpo1 PF08389.7 XP_011274423.1 - 2e-25 89.4 1.6 2e-25 89.4 1.1 3.6 5 0 0 5 5 5 1 Exportin 1-like protein IBN_N PF03810.14 XP_011274423.1 - 1.1e-11 44.4 0.9 8.6e-10 38.3 0.1 3.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT_EZ PF13513.1 XP_011274423.1 - 0.047 14.1 0.0 17 6.0 0.0 4.0 3 0 0 3 3 3 0 HEAT-like repeat HalX PF08663.5 XP_011274424.1 - 0.6 10.1 5.0 6.3 6.8 0.1 2.4 2 0 0 2 2 2 0 HalX domain TRAPPC9-Trs120 PF08626.6 XP_011274427.1 - 5e-244 812.4 35.5 5.7e-244 812.2 24.6 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TPR_12 PF13424.1 XP_011274427.1 - 0.047 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.1 XP_011274427.1 - 0.068 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 TPR repeat Proteasome PF00227.21 XP_011274428.1 - 1.2e-40 138.8 0.2 1.8e-40 138.2 0.1 1.3 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 XP_011274428.1 - 5.2e-14 51.2 0.1 1.2e-13 50.0 0.1 1.7 1 0 0 1 1 1 1 Proteasome beta subunits C terminal Formyl_trans_N PF00551.14 XP_011274429.1 - 5.3e-41 140.1 0.6 3.3e-40 137.5 0.4 1.8 1 1 0 1 1 1 1 Formyl transferase Iso_dh PF00180.15 XP_011274430.1 - 2.2e-99 332.7 0.2 2.5e-99 332.5 0.1 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF4591 PF15261.1 XP_011274430.1 - 0.14 12.4 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4591) ThiF PF00899.16 XP_011274431.1 - 9.8e-34 116.1 0.0 1.9e-33 115.1 0.0 1.5 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 XP_011274431.1 - 9.2e-27 92.4 0.7 1.9e-26 91.3 0.5 1.6 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 XP_011274431.1 - 2.5e-19 68.3 5.1 4.3e-19 67.6 3.6 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 XP_011274431.1 - 1.2e-07 31.7 0.7 3.9e-07 30.0 0.5 1.9 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_C PF09358.5 XP_011274431.1 - 0.0051 16.9 0.1 0.017 15.2 0.0 1.9 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain Pyr_redox PF00070.22 XP_011274431.1 - 0.16 12.4 0.8 1.4 9.3 0.1 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase RhoGAP PF00620.22 XP_011274432.1 - 2.1e-35 121.5 1.3 2.2e-34 118.2 0.9 2.2 1 1 0 1 1 1 1 RhoGAP domain BAR PF03114.13 XP_011274433.1 - 1e-50 172.4 5.2 1.3e-50 172.1 3.6 1.1 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.1 XP_011274433.1 - 1.9e-14 52.9 0.0 3.6e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 XP_011274433.1 - 5.2e-14 51.3 0.3 1.2e-13 50.2 0.0 1.8 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 XP_011274433.1 - 2.7e-10 39.5 0.0 8.2e-10 38.0 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain AA_permease PF00324.16 XP_011274435.1 - 7.3e-73 245.5 45.5 1.1e-38 132.8 10.4 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 XP_011274435.1 - 3.2e-17 62.2 46.4 1.3e-09 37.1 9.5 2.1 1 1 1 2 2 2 2 Amino acid permease Orai-1 PF07856.7 XP_011274435.1 - 6.8 6.2 12.1 0.95 9.0 4.8 2.3 2 1 0 2 2 2 0 Mediator of CRAC channel activity SeleniumBinding PF11524.3 XP_011274436.1 - 0.11 12.6 1.0 0.19 11.9 0.7 1.4 1 0 0 1 1 1 0 Selenium binding protein AA_permease PF00324.16 XP_011274437.1 - 5.9e-90 301.8 42.7 7.3e-90 301.5 29.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 XP_011274437.1 - 2.9e-27 95.3 45.5 3.6e-27 94.9 31.6 1.1 1 0 0 1 1 1 1 Amino acid permease DUF334 PF03904.8 XP_011274437.1 - 0.14 11.4 0.6 0.57 9.4 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF334) MFS_1 PF07690.11 XP_011274438.1 - 3.4e-12 45.7 0.5 4.5e-12 45.3 0.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.11 XP_011274439.1 - 1.4e-12 47.0 19.5 2.6e-10 39.5 5.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4341 PF14241.1 XP_011274439.1 - 0.019 14.6 0.4 1.6 8.4 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4341) AA_permease PF00324.16 XP_011274440.1 - 1.7e-86 290.4 36.5 2.1e-86 290.1 25.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 XP_011274440.1 - 6.3e-29 100.7 40.6 7.7e-29 100.4 28.1 1.1 1 0 0 1 1 1 1 Amino acid permease ERCC4 PF02732.10 XP_011274441.1 - 5.8e-26 90.9 0.5 1.1e-25 90.0 0.3 1.5 1 0 0 1 1 1 1 ERCC4 domain RRN7 PF11781.3 XP_011274443.1 - 2.6e-06 26.8 2.8 4.7e-06 26.0 1.9 1.4 1 0 0 1 1 1 1 RNA polymerase I-specific transcription initiation factor Rrn7 FMN_dh PF01070.13 XP_011274444.1 - 1.1e-119 399.4 0.0 2e-119 398.6 0.0 1.4 2 0 0 2 2 2 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 XP_011274444.1 - 1.4e-24 85.6 0.0 3.4e-24 84.4 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 XP_011274444.1 - 2e-07 30.2 0.0 3.3e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 XP_011274444.1 - 0.0025 16.7 0.0 0.0042 16.0 0.0 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 XP_011274444.1 - 0.006 15.7 0.0 0.0092 15.1 0.0 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase DUF4351 PF14261.1 XP_011274444.1 - 0.11 12.3 1.9 1.2 9.0 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4351) LRR_4 PF12799.2 XP_011274445.1 - 3.2e-52 173.4 74.5 1.6e-11 43.5 1.5 6.7 3 1 6 9 9 9 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 XP_011274445.1 - 9.6e-29 98.9 78.1 7.1e-08 32.0 2.6 5.5 1 1 7 8 8 8 8 Leucine rich repeat LRR_9 PF14580.1 XP_011274445.1 - 1.3e-12 47.6 17.7 3.3e-06 26.7 0.3 3.3 1 1 2 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.28 XP_011274445.1 - 9.1e-11 40.2 41.7 0.25 11.5 0.2 10.6 11 0 0 11 11 11 6 Leucine Rich Repeat LRR_7 PF13504.1 XP_011274445.1 - 4.9e-10 37.9 20.3 3 8.4 0.0 10.2 11 0 0 11 11 11 4 Leucine rich repeat LRR_6 PF13516.1 XP_011274445.1 - 5.5e-10 38.2 32.4 0.32 11.1 0.7 10.3 8 4 2 10 10 10 4 Leucine Rich repeat DUF3744 PF12558.3 XP_011274445.1 - 0.53 10.7 16.0 0.46 10.9 0.4 4.8 1 1 5 6 6 6 0 ATP-binding cassette cobalt transporter LRR_3 PF07725.7 XP_011274445.1 - 2.9 7.8 15.8 19 5.2 0.0 6.2 6 0 0 6 6 6 0 Leucine Rich Repeat PP-binding PF00550.20 XP_011274446.1 - 9.2e-11 41.8 0.5 1.3e-10 41.3 0.3 1.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 XP_011274446.1 - 0.00024 21.0 0.4 0.00035 20.5 0.3 1.3 1 0 0 1 1 1 1 Acyl-carrier DUF1493 PF07377.7 XP_011274446.1 - 0.00025 21.0 0.3 0.0004 20.4 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1493) Exotox-A_bind PF09101.5 XP_011274446.1 - 0.036 13.1 0.1 0.038 13.1 0.0 1.2 1 0 0 1 1 1 0 Exotoxin A binding Ded_cyto PF06920.8 XP_011274447.1 - 6.9e-25 87.3 0.2 1.8e-24 86.0 0.1 1.7 1 0 0 1 1 1 1 Dedicator of cytokinesis CinA PF02464.12 XP_011274448.1 - 2.3e-33 114.8 0.0 5e-33 113.7 0.0 1.5 1 1 0 1 1 1 1 Competence-damaged protein Proteasom_Rpn13 PF04683.8 XP_011274449.1 - 3.1e-23 81.6 0.0 6.7e-23 80.5 0.0 1.6 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor ROS_MUCR PF05443.6 XP_011274449.1 - 0.022 14.5 0.1 0.044 13.5 0.1 1.6 1 1 0 1 1 1 0 ROS/MUCR transcriptional regulator protein DUF1292 PF06949.6 XP_011274449.1 - 0.2 12.0 0.3 0.2 12.0 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1292) Mcp5_PH PF12814.2 XP_011274450.1 - 6.9e-41 139.0 0.1 2.8e-40 137.0 0.0 2.2 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology Filament PF00038.16 XP_011274450.1 - 0.00021 20.8 23.1 0.00021 20.8 16.0 9.0 5 3 5 10 10 10 3 Intermediate filament protein Fib_alpha PF08702.5 XP_011274450.1 - 0.0025 17.9 5.3 0.0025 17.9 3.7 9.6 7 1 3 10 10 10 4 Fibrinogen alpha/beta chain family DUF641 PF04859.7 XP_011274450.1 - 0.036 13.8 0.1 0.036 13.8 0.1 9.6 5 2 2 8 8 8 0 Plant protein of unknown function (DUF641) IncA PF04156.9 XP_011274450.1 - 2.1 7.9 155.6 0.19 11.2 0.7 12.1 5 3 4 10 10 10 0 IncA protein BTB PF00651.26 XP_011274451.1 - 3.3e-06 27.0 0.0 5.8e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Amidohydro_2 PF04909.9 XP_011274452.1 - 1.4e-06 28.1 0.0 6.1e-06 25.9 0.0 2.0 1 1 1 2 2 2 1 Amidohydrolase Amidohydro_4 PF13147.1 XP_011274452.1 - 0.00033 20.7 0.0 0.00041 20.4 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase Diphthamide_syn PF01866.12 XP_011274453.1 - 4.1e-43 147.7 0.0 2.4e-21 76.2 0.0 2.3 2 0 0 2 2 2 2 Putative diphthamide synthesis protein WD40 PF00400.27 XP_011274453.1 - 2.1e-38 128.8 22.3 3.3e-11 42.6 0.3 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Sel1 PF08238.7 XP_011274453.1 - 6.7e-18 64.7 32.6 0.0031 18.0 0.0 9.9 10 0 0 10 10 10 5 Sel1 repeat TPR_11 PF13414.1 XP_011274453.1 - 4.4e-09 35.8 8.1 0.022 14.3 0.1 4.2 3 1 1 4 4 4 3 TPR repeat TPR_2 PF07719.12 XP_011274453.1 - 2.1e-06 27.2 2.9 0.056 13.3 0.4 4.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 XP_011274453.1 - 1.2e-05 24.7 2.1 0.0028 17.3 0.1 4.4 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 XP_011274453.1 - 9.5e-05 21.8 6.2 0.067 12.8 0.4 4.8 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 XP_011274453.1 - 0.00011 22.0 4.0 0.88 9.5 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 XP_011274453.1 - 0.00038 20.0 13.0 0.026 14.2 0.2 4.8 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 XP_011274453.1 - 0.014 16.0 3.7 0.75 10.5 0.3 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 XP_011274453.1 - 0.19 11.9 4.9 17 5.9 0.0 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 XP_011274453.1 - 6.7 7.4 9.6 19 6.0 0.0 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat PNP_UDP_1 PF01048.15 XP_011274454.1 - 7.2e-46 156.0 0.0 8.3e-46 155.8 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Ribonuc_red_lgC PF02867.10 XP_011274455.1 - 1.4e-214 713.6 0.0 2e-214 713.1 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 XP_011274455.1 - 8e-24 83.2 0.0 2.6e-23 81.6 0.0 1.9 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 XP_011274455.1 - 6.8e-16 58.4 0.0 3e-15 56.3 0.0 2.2 1 0 0 1 1 1 1 ATP cone domain NRDD PF13597.1 XP_011274455.1 - 0.00044 18.4 0.0 0.00068 17.8 0.0 1.2 1 0 0 1 1 1 1 Anaerobic ribonucleoside-triphosphate reductase LCCL PF03815.14 XP_011274456.1 - 4.4e-08 32.9 0.0 1.1e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 LCCL domain DUF4153 PF13687.1 XP_011274456.1 - 0.0089 15.5 2.6 0.0089 15.5 1.8 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4153) HA2 PF04408.18 XP_011274457.1 - 8.3e-28 96.4 0.9 4.4e-25 87.6 0.0 4.1 4 0 0 4 4 4 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 XP_011274457.1 - 4.3e-24 84.5 0.1 1.9e-23 82.4 0.0 2.1 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 XP_011274457.1 - 1.9e-13 50.0 0.0 6.4e-13 48.3 0.0 1.9 2 0 0 2 2 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 XP_011274457.1 - 3.2e-07 29.9 0.4 1.7e-06 27.6 0.1 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_22 PF13401.1 XP_011274457.1 - 5.9e-07 29.6 0.1 1.5e-06 28.4 0.1 1.7 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.9 XP_011274457.1 - 0.00065 19.4 0.0 0.0012 18.5 0.0 1.4 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_14 PF13173.1 XP_011274457.1 - 0.0011 18.9 0.4 0.0092 15.8 0.3 2.3 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 XP_011274457.1 - 0.0012 17.8 0.0 0.0033 16.3 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_10 PF12846.2 XP_011274457.1 - 0.0054 16.2 0.3 1.6 8.1 0.0 2.4 2 0 0 2 2 2 1 AAA-like domain IstB_IS21 PF01695.12 XP_011274457.1 - 0.0092 15.4 0.1 2.5 7.4 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein ABC_tran PF00005.22 XP_011274457.1 - 0.0098 16.1 0.3 0.057 13.7 0.0 2.3 2 0 0 2 2 2 1 ABC transporter AAA_30 PF13604.1 XP_011274457.1 - 0.013 15.1 0.0 0.029 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 XP_011274457.1 - 0.013 14.9 0.0 0.026 13.9 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain PhoH PF02562.11 XP_011274457.1 - 0.014 14.6 0.0 0.045 12.9 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein Arch_ATPase PF01637.13 XP_011274457.1 - 0.018 14.7 0.0 0.018 14.7 0.0 2.2 3 0 0 3 3 2 0 Archaeal ATPase Peptidase_S41 PF03572.13 XP_011274457.1 - 0.02 14.3 0.5 0.06 12.7 0.3 1.8 1 1 0 1 1 1 0 Peptidase family S41 NB-ARC PF00931.17 XP_011274457.1 - 0.02 13.7 0.1 0.044 12.6 0.1 1.6 1 0 0 1 1 1 0 NB-ARC domain AAA_19 PF13245.1 XP_011274457.1 - 0.03 14.0 0.0 0.09 12.5 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain KaiC PF06745.8 XP_011274457.1 - 0.033 13.3 0.0 0.058 12.4 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_29 PF13555.1 XP_011274457.1 - 0.07 12.6 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 XP_011274457.1 - 0.098 12.9 0.3 0.098 12.9 0.2 4.0 3 2 1 4 4 2 0 AAA domain NACHT PF05729.7 XP_011274457.1 - 0.13 11.9 0.2 0.43 10.2 0.1 1.9 2 0 0 2 2 2 0 NACHT domain ResIII PF04851.10 XP_011274457.1 - 0.24 11.1 0.0 0.24 11.1 0.0 3.7 4 1 1 5 5 4 0 Type III restriction enzyme, res subunit Sec6 PF06046.8 XP_011274458.1 - 2.1e-151 504.8 21.4 2.7e-151 504.4 14.8 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec6 Tctex-1 PF03645.8 XP_011274459.1 - 4.8e-09 35.9 0.6 5.6e-09 35.7 0.4 1.0 1 0 0 1 1 1 1 Tctex-1 family DUF128 PF01995.11 XP_011274459.1 - 0.016 14.1 0.6 0.022 13.6 0.3 1.3 1 1 0 1 1 1 0 Domain of unknown function DUF128 DUF1374 PF07118.6 XP_011274459.1 - 0.056 13.5 4.9 0.071 13.2 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1374) DUF2621 PF11084.3 XP_011274459.1 - 0.071 12.7 0.1 0.089 12.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2621) Spore_GerAC PF05504.6 XP_011274460.1 - 0.03 14.1 0.6 0.03 14.1 0.4 2.3 2 0 0 2 2 2 0 Spore germination B3/ GerAC like, C-terminal GnHR_trans PF12369.3 XP_011274460.1 - 0.71 10.3 3.5 0.41 11.1 0.2 2.2 2 0 0 2 2 2 0 Gonadotropin hormone receptor transmembrane region Aldedh PF00171.17 XP_011274463.1 - 7.4e-182 604.7 0.1 8.4e-182 604.6 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 XP_011274463.1 - 0.16 11.1 0.0 2.5 7.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Ribosomal_S24e PF01282.14 XP_011274464.1 - 1.4e-35 120.9 0.1 2.5e-35 120.1 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S24e PH PF00169.24 XP_011274465.1 - 6.2e-14 52.0 1.2 6.2e-14 52.0 0.8 2.0 2 0 0 2 2 2 1 PH domain IL2 PF00715.12 XP_011274465.1 - 2.9 7.6 7.0 3.6 7.2 1.1 2.6 2 0 0 2 2 2 0 Interleukin 2 Glycos_transf_1 PF00534.15 XP_011274466.1 - 1.7e-16 60.1 0.0 3.8e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 XP_011274466.1 - 0.0047 16.6 0.0 0.0093 15.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 XP_011274466.1 - 0.008 16.3 0.0 0.017 15.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Mob1_phocein PF03637.12 XP_011274467.1 - 5.7e-73 244.2 0.3 7.6e-73 243.8 0.2 1.1 1 0 0 1 1 1 1 Mob1/phocein family Mito_carr PF00153.22 XP_011274468.1 - 1.6e-59 197.6 0.3 2.7e-19 68.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein 6PF2K PF01591.13 XP_011274469.1 - 1.1e-79 266.5 0.1 2.4e-79 265.5 0.0 1.6 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 XP_011274469.1 - 5.6e-29 101.2 0.3 1.5e-28 99.9 0.0 1.9 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 XP_011274469.1 - 8.5e-07 28.9 0.0 3.4e-06 27.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 XP_011274469.1 - 1.6e-05 24.0 0.1 9.9e-05 21.5 0.1 2.1 1 1 0 1 1 1 1 Zeta toxin AAA_17 PF13207.1 XP_011274469.1 - 0.0023 18.7 0.4 0.012 16.4 0.0 2.5 2 1 0 2 2 2 1 AAA domain KTI12 PF08433.5 XP_011274469.1 - 0.0063 15.7 0.1 0.025 13.7 0.1 1.9 1 1 0 1 1 1 1 Chromatin associated protein KTI12 MMR_HSR1 PF01926.18 XP_011274469.1 - 0.026 14.4 0.0 1.2 9.0 0.0 3.0 2 2 0 2 2 2 0 50S ribosome-binding GTPase Metallopep PF12044.3 XP_011274470.1 - 1.8e-163 543.9 0.0 2.3e-163 543.6 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.12 XP_011274470.1 - 1.6e-09 37.7 0.0 5.5e-09 35.9 0.0 1.9 2 0 0 2 2 2 1 Jacalin-like lectin domain Reprolysin_5 PF13688.1 XP_011274470.1 - 0.016 15.1 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 XP_011274470.1 - 0.019 15.4 0.0 0.06 13.8 0.0 1.9 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.19 XP_011274470.1 - 0.075 12.4 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) Reprolysin_2 PF13574.1 XP_011274470.1 - 0.1 12.6 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Sec23_trunk PF04811.10 XP_011274471.1 - 6e-66 222.2 0.0 1e-65 221.5 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 XP_011274471.1 - 7.1e-24 83.2 0.1 2e-23 81.7 0.0 1.9 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 XP_011274471.1 - 1e-16 61.2 0.0 2.1e-16 60.2 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 XP_011274471.1 - 2.5e-15 55.7 7.0 4.2e-15 55.0 4.8 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 XP_011274471.1 - 6.3e-06 25.7 0.0 1.7e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat COX4 PF02936.9 XP_011274472.1 - 2.8e-38 130.8 0.1 3.4e-38 130.5 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV COG5 PF10392.4 XP_011274474.1 - 1e-33 116.0 6.9 1e-33 116.0 4.8 2.7 4 1 0 4 4 4 1 Golgi transport complex subunit 5 Ank_2 PF12796.2 XP_011274475.1 - 2.3e-50 168.8 2.3 4.2e-21 75.0 0.1 3.1 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 XP_011274475.1 - 1.3e-31 106.7 1.9 2.2e-11 42.9 0.1 5.6 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.1 XP_011274475.1 - 3.6e-25 87.8 1.1 7.4e-10 39.0 0.0 4.6 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 XP_011274475.1 - 1.3e-23 82.4 0.4 3e-09 36.8 0.1 4.6 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 XP_011274475.1 - 5e-23 78.8 0.1 1.9e-08 33.7 0.0 5.7 5 0 0 5 5 5 3 Ankyrin repeat DUF4112 PF13430.1 XP_011274476.1 - 4e-31 107.0 0.1 6.2e-31 106.4 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) DUF605 PF04652.11 XP_011274476.1 - 0.00044 19.7 0.5 0.00045 19.7 0.4 1.1 1 0 0 1 1 1 1 Vta1 like WD40 PF00400.27 XP_011274477.1 - 4e-34 115.2 13.2 4.7e-08 32.6 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 XP_011274477.1 - 5.4e-10 39.3 0.1 0.0055 16.4 0.0 3.2 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A DUF77 PF01910.12 XP_011274478.1 - 1e-26 92.4 0.2 1.3e-26 92.1 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF77 ComK PF06338.6 XP_011274478.1 - 0.092 12.1 0.1 0.7 9.2 0.0 2.0 2 0 0 2 2 2 0 ComK protein Sas10_Utp3 PF04000.10 XP_011274479.1 - 7.7e-12 45.2 2.0 7.7e-12 45.2 1.4 2.9 3 0 0 3 3 3 1 Sas10/Utp3/C1D family EDR1 PF14381.1 XP_011274479.1 - 0.072 12.6 1.5 0.13 11.8 0.8 1.6 1 1 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 Neur_chan_memb PF02932.11 XP_011274479.1 - 2.2 8.1 11.8 5.3 6.8 0.3 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Ribosomal_S8e PF01201.17 XP_011274480.1 - 2.9e-40 137.4 4.6 1e-39 135.7 3.2 1.8 1 1 0 1 1 1 1 Ribosomal protein S8e DUF3959 PF13105.1 XP_011274480.1 - 6.2 6.0 8.5 1.7 7.8 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3959) Nol1_Nop2_Fmu PF01189.12 XP_011274481.1 - 3.3e-23 82.4 0.0 8.1e-23 81.1 0.0 1.7 1 1 0 1 1 1 1 NOL1/NOP2/sun family Iso_dh PF00180.15 XP_011274482.1 - 6.8e-99 331.0 0.0 1.4e-98 330.0 0.0 1.3 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Metallophos PF00149.23 XP_011274485.1 - 1.6e-10 40.7 1.6 1.6e-10 40.7 1.1 2.4 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 XP_011274485.1 - 4.3e-05 23.3 0.0 0.00026 20.8 0.0 2.1 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 XP_011274486.1 - 1.7e-09 37.3 8.8 1.7e-09 37.3 6.1 2.7 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 XP_011274486.1 - 0.00014 21.6 0.0 0.0015 18.3 0.0 2.3 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Peptidase_M20 PF01546.23 XP_011274487.1 - 2.8e-27 95.4 0.0 3.5e-27 95.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 XP_011274487.1 - 2.4e-19 69.1 0.1 4.1e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 XP_011274487.1 - 0.043 13.5 0.0 0.077 12.7 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M28 YbgS PF13985.1 XP_011274488.1 - 1.6 8.6 4.6 1.6 8.6 2.4 1.5 1 1 0 1 1 1 0 YbgS-like protein DUF2431 PF10354.4 XP_011274489.1 - 1.8e-49 167.8 0.1 2.5e-49 167.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) Iso_dh PF00180.15 XP_011274490.1 - 1.2e-80 271.1 0.2 1.3e-80 270.9 0.1 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Complex1_LYR_2 PF13233.1 XP_011274491.1 - 7.6e-15 55.2 4.8 1.2e-14 54.6 3.3 1.4 1 1 0 1 1 1 1 Complex1_LYR-like DUF1151 PF06625.6 XP_011274491.1 - 0.073 12.8 3.8 0.072 12.8 1.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1151) UBN2 PF14223.1 XP_011274491.1 - 0.33 10.7 3.4 0.43 10.3 1.7 1.8 1 1 1 2 2 2 0 gag-polypeptide of LTR copia-type Nucleoporin2 PF04096.9 XP_011274495.1 - 1.3e-47 161.1 0.0 2e-47 160.5 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 XP_011274495.1 - 8e-47 158.1 445.4 3.4e-13 49.8 24.5 12.8 3 2 8 11 11 11 11 Nucleoporin FG repeat region SRF-TF PF00319.13 XP_011274496.1 - 3e-23 80.8 0.2 4.6e-23 80.2 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF2360 PF10152.4 XP_011274496.1 - 1.2 9.4 14.9 0.3 11.3 8.2 1.5 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) CDC45 PF02724.9 XP_011274496.1 - 1.3 7.0 7.6 0.56 8.1 0.4 2.0 2 0 0 2 2 2 0 CDC45-like protein DUF3729 PF12526.3 XP_011274496.1 - 2.4 9.5 12.3 4.6 8.6 8.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3729) Totivirus_coat PF05518.6 XP_011274496.1 - 4.3 5.0 11.4 5.4 4.7 7.9 1.1 1 0 0 1 1 1 0 Totivirus coat protein DUF3824 PF12868.2 XP_011274496.1 - 9.5 7.1 22.7 20 6.1 15.7 1.4 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) PWWP PF00855.12 XP_011274497.1 - 7.2e-12 45.3 0.2 7.2e-12 45.3 0.1 3.1 3 1 0 3 3 3 1 PWWP domain YL1 PF05764.8 XP_011274497.1 - 0.0027 17.3 16.7 0.0027 17.3 11.6 3.4 3 0 0 3 3 3 1 YL1 nuclear protein Aldo_ket_red PF00248.16 XP_011274498.1 - 1.4e-60 204.5 0.0 1.6e-60 204.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 XP_011274499.1 - 1.5e-64 217.5 0.0 1.7e-64 217.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF2120 PF09893.4 XP_011274499.1 - 0.0028 17.6 0.2 0.23 11.3 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized protein conserved in archaea (DUF2120) DUF2638 PF10937.3 XP_011274500.1 - 3.3e-12 47.4 2.8 6.5e-12 46.4 2.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2638) Proteasome PF00227.21 XP_011274501.1 - 2.8e-23 82.2 0.0 3.6e-23 81.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF2244 PF10003.4 XP_011274501.1 - 0.16 11.3 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) PDEase_II PF02112.10 XP_011274502.1 - 2.5e-73 246.8 15.9 3.3e-73 246.5 11.0 1.1 1 0 0 1 1 1 1 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 XP_011274502.1 - 2.7e-07 30.3 0.4 4.1e-07 29.7 0.3 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Clat_adaptor_s PF01217.15 XP_011274503.1 - 4.1e-10 39.5 1.3 4.1e-10 39.5 0.9 2.1 2 1 0 2 2 2 1 Clathrin adaptor complex small chain Adap_comp_sub PF00928.16 XP_011274503.1 - 7.4e-09 35.0 0.5 1.1e-08 34.4 0.4 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Sec63 PF02889.11 XP_011274506.1 - 1.7e-48 165.5 0.0 3.3e-48 164.5 0.0 1.5 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 XP_011274506.1 - 2.5e-28 98.6 0.1 6e-28 97.4 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 XP_011274506.1 - 6.5e-11 42.4 0.3 6.5e-11 42.4 0.2 3.3 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 XP_011274506.1 - 1.4e-09 37.6 0.0 3.6e-09 36.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 XP_011274506.1 - 0.0013 18.8 0.0 0.0034 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 XP_011274506.1 - 0.014 14.2 0.0 0.027 13.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.1 XP_011274506.1 - 0.032 13.9 0.0 0.075 12.7 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Palm_thioest PF02089.10 XP_011274507.1 - 3.6e-46 157.3 0.2 4.2e-46 157.1 0.1 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.8 XP_011274507.1 - 2.1e-06 27.5 0.0 4.1e-06 26.5 0.0 1.5 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 XP_011274507.1 - 2.7e-06 27.4 0.0 6.1e-06 26.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 XP_011274507.1 - 6.3e-06 25.6 0.0 1e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_2 PF01674.13 XP_011274507.1 - 2e-05 24.0 0.0 0.00025 20.4 0.0 2.0 1 1 0 1 1 1 1 Lipase (class 2) Abhydrolase_1 PF00561.15 XP_011274507.1 - 8e-05 22.2 0.0 0.0013 18.3 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 XP_011274507.1 - 0.00075 19.2 0.0 0.0016 18.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 XP_011274507.1 - 0.0013 18.2 0.1 0.76 9.1 0.1 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase FSH1 PF03959.8 XP_011274507.1 - 0.0041 16.5 0.1 0.018 14.4 0.1 2.0 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Thioesterase PF00975.15 XP_011274507.1 - 0.0048 17.1 0.0 0.0068 16.6 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain DUF1746 PF08508.5 XP_011274508.1 - 6.9e-09 35.6 2.1 1.4e-08 34.6 1.4 1.5 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) LETM1 PF07766.8 XP_011274509.1 - 1.1e-100 336.1 3.9 2.1e-100 335.2 2.7 1.5 1 0 0 1 1 1 1 LETM1-like protein dUTPase PF00692.14 XP_011274510.1 - 2.3e-41 140.2 0.1 2.7e-41 140.0 0.0 1.0 1 0 0 1 1 1 1 dUTPase Sedlin_N PF04628.8 XP_011274512.1 - 5e-40 136.4 0.7 5.4e-40 136.3 0.5 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 XP_011274512.1 - 7.7e-09 35.3 0.4 8.5e-09 35.2 0.3 1.1 1 0 0 1 1 1 1 Sybindin-like family MIS13 PF08202.6 XP_011274513.1 - 5.7e-44 150.3 26.3 5.7e-44 150.3 18.2 2.4 2 1 0 2 2 2 1 Mis12-Mtw1 protein family PAP2 PF01569.16 XP_011274514.1 - 7.2e-19 67.7 0.9 1.8e-18 66.4 0.7 1.7 1 0 0 1 1 1 1 PAP2 superfamily Fer4_5 PF12801.2 XP_011274514.1 - 1.4 8.7 5.9 0.59 9.9 1.2 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Peptidase_M20 PF01546.23 XP_011274515.1 - 1.3e-24 86.7 0.0 2e-24 86.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 XP_011274515.1 - 1.9e-17 62.9 0.5 3.6e-17 62.1 0.3 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Thymidylate_kin PF02223.12 XP_011274516.1 - 6.9e-35 120.1 0.3 1e-25 90.2 0.0 2.0 1 1 1 2 2 2 2 Thymidylate kinase AAA_28 PF13521.1 XP_011274516.1 - 4.9e-05 23.3 0.0 0.0013 18.6 0.0 1.9 1 1 1 2 2 2 1 AAA domain KTI12 PF08433.5 XP_011274516.1 - 0.00029 20.1 0.4 0.0013 17.9 0.3 2.0 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_14 PF13173.1 XP_011274516.1 - 0.00096 19.0 0.6 0.0053 16.6 0.4 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 XP_011274516.1 - 0.0047 17.2 1.8 0.13 12.6 1.3 2.3 1 1 0 1 1 1 1 AAA domain SRP54 PF00448.17 XP_011274516.1 - 0.024 14.0 0.0 0.066 12.6 0.0 1.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Arf PF00025.16 XP_011274516.1 - 0.028 13.6 0.5 0.15 11.3 0.0 2.0 2 0 0 2 2 2 0 ADP-ribosylation factor family PPK2 PF03976.9 XP_011274516.1 - 0.036 13.3 0.0 0.065 12.5 0.0 1.4 1 0 0 1 1 1 0 Polyphosphate kinase 2 (PPK2) APS_kinase PF01583.15 XP_011274516.1 - 0.064 12.9 0.0 0.17 11.4 0.0 1.7 2 0 0 2 2 2 0 Adenylylsulphate kinase MobB PF03205.9 XP_011274516.1 - 0.074 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 XP_011274516.1 - 0.093 13.5 0.3 0.17 12.6 0.2 1.7 1 1 0 1 1 1 0 AAA domain ArgK PF03308.11 XP_011274516.1 - 0.15 10.7 0.1 0.36 9.5 0.0 1.6 2 0 0 2 2 2 0 ArgK protein Clat_adaptor_s PF01217.15 XP_011274517.1 - 1.3e-48 164.3 4.9 1.4e-48 164.2 3.4 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain HPD PF05044.7 XP_011274517.1 - 0.037 13.6 1.8 0.044 13.4 1.3 1.1 1 0 0 1 1 1 0 Homeo-prospero domain AAA PF00004.24 XP_011274518.1 - 4.6e-57 191.8 0.0 8.9e-43 145.6 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 XP_011274518.1 - 2.6e-23 81.8 0.6 6.9e-23 80.4 0.4 1.8 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 XP_011274518.1 - 1.4e-10 41.4 4.2 9.4e-05 22.4 0.0 4.0 3 1 1 4 4 4 2 AAA ATPase domain AAA_17 PF13207.1 XP_011274518.1 - 7e-08 33.3 0.1 0.025 15.3 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 XP_011274518.1 - 1.6e-06 28.2 0.2 0.1 12.7 0.0 4.2 4 1 0 4 4 3 2 AAA domain AAA_14 PF13173.1 XP_011274518.1 - 2.1e-05 24.4 0.0 0.18 11.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 XP_011274518.1 - 2.1e-05 24.4 0.0 0.12 12.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 XP_011274518.1 - 2.8e-05 23.5 0.7 1.2 8.4 0.1 4.1 2 2 1 4 4 4 1 AAA domain Arch_ATPase PF01637.13 XP_011274518.1 - 3.7e-05 23.5 7.2 0.00099 18.8 0.1 4.2 2 1 2 4 4 4 1 Archaeal ATPase Zeta_toxin PF06414.7 XP_011274518.1 - 0.00016 20.8 0.0 0.63 9.1 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin ABC_tran PF00005.22 XP_011274518.1 - 0.00017 21.8 3.5 0.034 14.4 0.0 3.6 4 0 0 4 4 3 1 ABC transporter Sigma54_activat PF00158.21 XP_011274518.1 - 0.00019 20.9 0.1 0.048 13.1 0.0 2.8 2 1 1 3 3 3 1 Sigma-54 interaction domain AAA_18 PF13238.1 XP_011274518.1 - 0.00027 21.2 3.7 0.35 11.1 0.0 4.0 4 1 0 4 4 2 2 AAA domain AAA_5 PF07728.9 XP_011274518.1 - 0.00029 20.5 0.0 0.96 9.1 0.0 3.4 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 XP_011274518.1 - 0.0004 20.3 0.0 0.019 14.8 0.0 3.3 4 0 0 4 4 3 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.17 XP_011274518.1 - 0.0005 20.2 0.0 1.3 9.2 0.0 2.7 2 0 0 2 2 2 2 RNA helicase DUF815 PF05673.8 XP_011274518.1 - 0.0018 17.2 0.0 0.1 11.5 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_10 PF12846.2 XP_011274518.1 - 0.0019 17.7 1.3 0.072 12.5 0.0 2.9 3 0 0 3 3 3 1 AAA-like domain NACHT PF05729.7 XP_011274518.1 - 0.003 17.2 0.5 6.1 6.4 0.0 3.7 3 1 0 3 3 3 0 NACHT domain RuvB_N PF05496.7 XP_011274518.1 - 0.0058 15.7 0.0 0.02 13.9 0.0 1.9 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 XP_011274518.1 - 0.0064 16.4 0.0 3 7.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 XP_011274518.1 - 0.0065 15.6 0.1 0.73 8.9 0.1 2.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF258 PF03193.11 XP_011274518.1 - 0.0079 15.3 0.4 0.02 14.0 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_24 PF13479.1 XP_011274518.1 - 0.015 14.9 0.3 4.5 6.7 0.2 3.1 3 0 0 3 3 3 0 AAA domain Viral_helicase1 PF01443.13 XP_011274518.1 - 0.015 14.8 0.0 3.1 7.2 0.0 3.0 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.12 XP_011274518.1 - 0.016 14.6 0.1 0.65 9.4 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_29 PF13555.1 XP_011274518.1 - 0.028 13.9 0.3 0.38 10.2 0.1 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain T2SE PF00437.15 XP_011274518.1 - 0.052 12.4 0.6 0.46 9.3 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_19 PF13245.1 XP_011274518.1 - 0.071 12.8 0.0 1.9 8.2 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain INCENP_ARK-bind PF03941.10 XP_011274519.1 - 6.2e-17 61.1 0.7 6.2e-17 61.1 0.5 3.2 4 0 0 4 4 4 1 Inner centromere protein, ARK binding region TPR_11 PF13414.1 XP_011274520.1 - 1.7e-20 72.4 4.3 3.9e-14 52.0 1.1 2.6 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 XP_011274520.1 - 1.2e-14 53.1 4.9 0.00016 21.0 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 XP_011274520.1 - 1.9e-08 33.5 1.1 0.19 11.7 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat Apc3 PF12895.2 XP_011274520.1 - 2.6e-05 24.2 1.9 5.9e-05 23.1 1.3 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 XP_011274520.1 - 3e-05 23.4 5.0 1.8 8.5 0.3 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 XP_011274520.1 - 4e-05 23.4 0.1 0.3 11.0 0.0 2.7 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 XP_011274520.1 - 0.00092 19.2 0.5 0.012 15.7 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 XP_011274520.1 - 0.0017 18.9 0.0 1.9 9.2 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 XP_011274520.1 - 0.0077 16.7 0.0 0.56 10.9 0.0 3.5 2 1 2 4 4 3 1 Tetratricopeptide repeat DUF3808 PF10300.4 XP_011274520.1 - 0.023 13.2 0.5 0.031 12.8 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) Fis1_TPR_C PF14853.1 XP_011274520.1 - 0.034 14.0 3.9 2.9 7.8 0.1 3.4 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat DUF2235 PF09994.4 XP_011274521.1 - 9.1e-78 261.4 0.0 1.4e-77 260.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) UCR_TM PF02921.9 XP_011274522.1 - 2.4e-20 72.4 1.0 4e-20 71.7 0.7 1.3 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 XP_011274522.1 - 2.8e-17 62.0 0.0 6.2e-17 60.9 0.0 1.6 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain Ribosomal_L7Ae PF01248.21 XP_011274524.1 - 5.3e-26 89.9 0.0 6.4e-26 89.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 XP_011274524.1 - 0.0017 18.1 0.0 0.0018 18.1 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.1 XP_011274524.1 - 0.0043 16.7 0.0 0.0054 16.4 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain CPSF_A PF03178.10 XP_011274525.1 - 4.9e-12 45.5 14.7 6.9e-11 41.8 3.2 3.9 3 1 0 4 4 4 2 CPSF A subunit region Pkinase PF00069.20 XP_011274526.1 - 5.2e-05 22.5 0.1 0.00012 21.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 XP_011274526.1 - 0.041 13.6 0.0 0.065 12.9 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.20 XP_011274527.1 - 0.00051 19.2 1.4 0.0058 15.8 0.4 2.3 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.18 XP_011274527.1 - 0.0077 15.9 0.1 0.014 15.1 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 XP_011274527.1 - 0.022 14.3 1.5 0.074 12.6 1.0 1.9 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.9 XP_011274527.1 - 0.17 10.8 0.2 0.76 8.8 0.1 2.0 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family ATP-synt_C PF00137.16 XP_011274528.1 - 2e-32 110.9 23.8 8.1e-19 67.2 7.6 2.1 2 0 0 2 2 2 2 ATP synthase subunit C DUF2970 PF11174.3 XP_011274528.1 - 0.86 9.2 8.5 0.15 11.6 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) Nucleopor_Nup85 PF07575.8 XP_011274529.1 - 2.4e-115 385.9 8.1 2.8e-115 385.6 5.6 1.0 1 0 0 1 1 1 1 Nup85 Nucleoporin TRP PF06011.7 XP_011274529.1 - 0.08 11.5 0.1 0.13 10.7 0.1 1.3 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel Urb2 PF10441.4 XP_011274530.1 - 6.1e-41 140.4 5.0 6.1e-41 140.4 3.4 2.3 3 0 0 3 3 3 1 Urb2/Npa2 family CYSTM PF12734.2 XP_011274530.1 - 1.2e-05 25.2 31.2 6.1e-05 23.0 21.6 2.1 1 1 0 1 1 1 1 Cysteine-rich TM module stress tolerance PRA1 PF03208.14 XP_011274531.1 - 6e-42 142.5 0.7 6.6e-42 142.4 0.5 1.0 1 0 0 1 1 1 1 PRA1 family protein Fig1 PF12351.3 XP_011274531.1 - 1.9 8.3 4.9 5.4 6.8 3.4 1.6 1 1 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 Peptidase_M1 PF01433.15 XP_011274532.1 - 1.8e-71 241.2 0.8 2.6e-71 240.7 0.5 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 XP_011274532.1 - 4.1e-39 133.4 0.3 9.5e-39 132.2 0.2 1.7 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 XP_011274532.1 - 1.4e-14 54.1 0.0 2.5e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 XP_011274532.1 - 0.044 13.7 1.8 0.21 11.5 1.3 2.2 1 1 0 1 1 1 0 M61 glycyl aminopeptidase Peptidase_M48 PF01435.13 XP_011274532.1 - 0.057 12.9 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M48 DUF2722 PF10846.3 XP_011274533.1 - 2.1e-28 99.5 29.9 1.5e-27 96.7 20.7 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2722) SHQ1 PF04925.10 XP_011274534.1 - 7.9e-62 208.0 0.8 1.3e-61 207.3 0.6 1.3 1 0 0 1 1 1 1 SHQ1 protein Diphthamide_syn PF01866.12 XP_011274535.1 - 4.9e-114 380.6 0.1 5.9e-114 380.4 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Lipoprotein_16 PF03923.8 XP_011274535.1 - 0.0075 15.6 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized lipoprotein COG6 PF06419.6 XP_011274536.1 - 4.9e-107 358.5 41.0 1.4e-83 281.1 14.9 2.2 1 1 1 2 2 2 2 Conserved oligomeric complex COG6 DUF1053 PF06327.9 XP_011274536.1 - 4.8 7.5 10.9 1.9 8.8 1.6 2.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1053) DUF2011 PF09428.5 XP_011274537.1 - 2.3e-29 101.9 7.9 3.4e-29 101.3 5.5 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2011) Atg14 PF10186.4 XP_011274537.1 - 2.6 6.9 9.2 3.7 6.4 6.4 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Pkinase PF00069.20 XP_011274538.1 - 0.011 14.8 0.5 1.4 7.9 0.2 2.4 2 0 0 2 2 2 0 Protein kinase domain PMP22_Claudin PF00822.15 XP_011274539.1 - 0.041 13.5 0.0 0.13 11.9 0.0 1.7 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family Pro_CA PF00484.14 XP_011274540.1 - 3.5e-38 131.0 0.0 4.6e-38 130.6 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase Glyco_hydro_15 PF00723.16 XP_011274541.1 - 2.5e-52 177.9 0.0 3.5e-52 177.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 IncA PF04156.9 XP_011274542.1 - 0.0044 16.6 0.7 0.0048 16.5 0.5 1.1 1 0 0 1 1 1 1 IncA protein DUF641 PF04859.7 XP_011274542.1 - 0.053 13.2 0.5 0.056 13.1 0.3 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Col_cuticle_N PF01484.12 XP_011274542.1 - 0.48 10.1 1.9 0.91 9.2 1.3 1.4 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain MFS_1 PF07690.11 XP_011274544.1 - 5.5e-48 163.4 46.8 2.4e-44 151.5 35.9 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 XP_011274544.1 - 1.3e-16 60.2 7.6 1.3e-16 60.2 5.3 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 XP_011274544.1 - 6.4e-15 54.3 18.7 6.4e-15 54.3 13.0 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 XP_011274544.1 - 0.0025 16.0 4.2 0.0049 15.0 2.9 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_1_like PF12832.2 XP_011274544.1 - 0.023 14.4 9.4 0.42 10.4 0.1 3.0 2 0 0 2 2 2 0 MFS_1 like family WD40 PF00400.27 XP_011274545.1 - 1.3e-14 53.3 2.0 0.00072 19.3 0.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat SprA-related PF12118.3 XP_011274545.1 - 0.032 13.5 19.5 0.047 13.0 13.5 1.2 1 0 0 1 1 1 0 SprA-related family TAF1D PF15333.1 XP_011274545.1 - 2.1 8.1 32.1 3.1 7.5 21.7 1.7 2 0 0 2 2 2 0 TATA box-binding protein-associated factor 1D GAGA_bind PF06217.7 XP_011274545.1 - 2.1 8.2 24.2 4.7 7.0 16.8 1.6 1 0 0 1 1 1 0 GAGA binding protein-like family Caldesmon PF02029.10 XP_011274545.1 - 5 5.4 41.6 6.9 4.9 28.8 1.1 1 0 0 1 1 1 0 Caldesmon Pkinase PF00069.20 XP_011274546.1 - 9.1e-38 129.8 0.0 1.8e-37 128.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011274546.1 - 1.2e-24 86.7 0.0 1.8e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 XP_011274546.1 - 2.3e-05 23.5 0.0 4.6e-05 22.5 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 XP_011274546.1 - 0.018 14.7 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Spc42p PF11544.3 XP_011274546.1 - 0.087 12.7 1.5 3 7.8 0.4 2.9 2 0 0 2 2 2 0 Spindle pole body component Spc42p Hist_deacetyl PF00850.14 XP_011274547.1 - 1.7e-96 323.2 0.0 2.2e-96 322.7 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 XP_011274547.1 - 1.9e-45 154.4 2.4 3.1e-45 153.7 1.7 1.4 1 0 0 1 1 1 1 Arb2 domain C2 PF00168.25 XP_011274548.1 - 0.00057 19.6 0.0 0.0014 18.4 0.0 1.6 1 0 0 1 1 1 1 C2 domain Pox_RNA_Pol_19 PF05320.7 XP_011274548.1 - 0.031 14.0 0.5 0.031 14.0 0.3 2.2 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Nop25 PF09805.4 XP_011274548.1 - 3.8 7.5 16.3 1 9.4 3.9 2.3 1 1 1 2 2 2 0 Nucleolar protein 12 (25kDa) C2 PF00168.25 XP_011274549.1 - 4e-11 42.6 0.0 9e-11 41.4 0.0 1.6 1 0 0 1 1 1 1 C2 domain RNA_pol_3_Rpc31 PF11705.3 XP_011274550.1 - 1.4e-55 188.7 15.7 1.6e-55 188.6 10.9 1.0 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 PGA2 PF07543.7 XP_011274551.1 - 6.1e-13 48.7 10.7 9.2e-07 28.7 3.8 2.1 1 1 1 2 2 2 2 Protein trafficking PGA2 UPF0193 PF05250.6 XP_011274551.1 - 0.0038 16.8 2.7 0.0045 16.5 1.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0193) Potyvirid-P3 PF13608.1 XP_011274551.1 - 0.019 14.0 0.4 0.022 13.8 0.3 1.0 1 0 0 1 1 1 0 Protein P3 of Potyviral polyprotein DUF1049 PF06305.6 XP_011274551.1 - 0.046 13.1 0.3 0.37 10.3 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Peroxin-3 PF04882.7 XP_011274551.1 - 0.12 11.0 1.5 0.15 10.7 1.1 1.0 1 0 0 1 1 1 0 Peroxin-3 Vpu PF00558.14 XP_011274551.1 - 0.37 10.3 6.1 1.6 8.3 0.2 2.2 2 0 0 2 2 2 0 Vpu protein APG6 PF04111.7 XP_011274551.1 - 4.1 6.3 8.7 4.7 6.1 6.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 CAP_GLY PF01302.20 XP_011274552.1 - 1.2e-21 76.2 1.0 2.2e-21 75.3 0.7 1.4 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 XP_011274552.1 - 1.2e-19 70.3 0.1 1.2e-19 70.3 0.1 1.7 2 0 0 2 2 2 1 Ubiquitin-like domain ubiquitin PF00240.18 XP_011274552.1 - 0.0032 16.8 0.1 0.012 14.9 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin family ApbE PF02424.10 XP_011274552.1 - 0.13 11.5 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 ApbE family UPRTase PF14681.1 XP_011274553.1 - 5.8e-75 251.0 0.0 7.3e-75 250.7 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 XP_011274553.1 - 0.0052 16.4 0.0 0.0071 16.0 0.0 1.4 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.8 XP_011274553.1 - 0.075 12.7 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) Actin PF00022.14 XP_011274554.1 - 4e-108 361.3 0.0 5.1e-108 361.0 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 XP_011274554.1 - 0.067 11.7 0.1 0.51 8.8 0.0 2.3 2 1 1 3 3 3 0 MreB/Mbl protein AAA PF00004.24 XP_011274555.1 - 1.6e-29 102.7 0.1 3.3e-29 101.7 0.0 1.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.13 XP_011274555.1 - 0.011 15.4 0.1 0.053 13.1 0.0 2.0 2 0 0 2 2 2 0 Bacterial dnaA protein MA3 PF02847.12 XP_011274557.1 - 4.2e-24 84.4 1.2 3.5e-23 81.4 0.1 2.7 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.14 XP_011274557.1 - 3.3e-23 82.2 7.5 3.3e-23 82.2 5.2 2.6 2 1 0 2 2 2 1 MIF4G domain Glt_symporter PF03616.9 XP_011274557.1 - 0.52 8.7 1.8 0.8 8.1 0.2 2.0 2 0 0 2 2 2 0 Sodium/glutamate symporter Pyr_redox_dim PF02852.17 XP_011274558.1 - 9.8e-41 138.2 0.1 2.4e-40 136.9 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 XP_011274558.1 - 2.8e-38 131.8 12.2 1.2e-36 126.5 8.5 3.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 XP_011274558.1 - 2.3e-20 72.7 8.3 2.3e-17 63.1 0.9 3.6 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 XP_011274558.1 - 4.9e-12 45.6 4.8 1.6e-10 40.6 0.2 2.6 2 1 1 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 XP_011274558.1 - 1.8e-10 41.2 1.5 6.3e-05 23.1 0.2 2.5 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 XP_011274558.1 - 8.2e-10 38.0 2.8 8.2e-10 38.0 1.9 2.4 1 1 1 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 XP_011274558.1 - 3.4e-09 36.5 3.3 0.00012 21.9 0.2 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 XP_011274558.1 - 1.2e-06 27.8 10.7 0.001 18.2 2.3 4.0 2 1 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.19 XP_011274558.1 - 1.2e-06 27.6 1.9 1.2e-06 27.6 1.3 3.4 3 1 1 4 4 4 1 FAD binding domain DAO PF01266.19 XP_011274558.1 - 1.4e-06 27.5 14.0 0.0095 14.8 0.1 4.2 3 1 1 4 4 4 3 FAD dependent oxidoreductase K_oxygenase PF13434.1 XP_011274558.1 - 6.4e-06 25.3 1.9 0.063 12.1 0.0 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 XP_011274558.1 - 0.00014 20.4 16.3 0.00055 18.5 0.6 4.1 3 1 1 4 4 4 1 HI0933-like protein Lycopene_cycl PF05834.7 XP_011274558.1 - 0.00022 20.2 0.7 0.0011 17.9 0.0 2.2 3 0 0 3 3 3 1 Lycopene cyclase protein Thi4 PF01946.12 XP_011274558.1 - 0.0019 17.3 1.5 0.0019 17.3 1.0 2.4 1 1 1 2 2 2 1 Thi4 family AlaDh_PNT_C PF01262.16 XP_011274558.1 - 0.003 17.1 2.1 0.16 11.4 0.1 2.8 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.9 XP_011274558.1 - 0.0044 16.4 0.4 0.0044 16.4 0.3 2.2 3 0 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 XP_011274558.1 - 0.014 15.0 0.4 0.014 15.0 0.3 2.7 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Chitin_synth_1 PF01644.12 XP_011274559.1 - 4.4e-83 276.9 0.6 6.7e-83 276.3 0.4 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 XP_011274559.1 - 5.4e-26 90.0 0.0 1.2e-25 89.0 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 XP_011274559.1 - 2e-25 89.1 0.8 1.9e-18 66.1 0.0 2.8 2 1 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.1 XP_011274559.1 - 9e-08 32.0 0.1 3.2e-07 30.2 0.1 1.9 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 XP_011274559.1 - 2.2e-06 27.6 0.0 5.1e-05 23.1 0.0 2.6 3 0 0 3 3 3 1 Glycosyltransferase like family 2 SCO1-SenC PF02630.9 XP_011274560.1 - 4.6e-71 237.9 0.1 7.3e-71 237.3 0.1 1.2 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 XP_011274560.1 - 9.7e-06 25.2 0.0 1.9e-05 24.3 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family YchF-GTPase_C PF06071.8 XP_011274561.1 - 3.1e-35 119.8 0.6 7.9e-35 118.5 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 XP_011274561.1 - 4.5e-12 45.9 0.0 9.6e-12 44.8 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.16 XP_011274561.1 - 0.00015 21.5 0.0 0.00042 20.0 0.0 1.7 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.13 XP_011274561.1 - 0.009 15.2 0.0 0.021 14.1 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B MobB PF03205.9 XP_011274561.1 - 0.05 13.3 0.2 8.3 6.1 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 XP_011274561.1 - 0.05 13.9 1.1 0.29 11.4 0.8 2.2 1 1 0 1 1 1 0 AAA domain SecA_PP_bind PF01043.15 XP_011274561.1 - 0.057 13.7 0.2 0.28 11.5 0.0 2.1 2 0 0 2 2 2 0 SecA preprotein cross-linking domain RRM_1 PF00076.17 XP_011274562.1 - 8e-13 47.8 0.7 1.6e-08 34.0 0.1 3.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 XP_011274562.1 - 1.5e-11 44.0 0.1 3e-09 36.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 XP_011274562.1 - 7.9e-09 35.2 0.8 0.00093 18.9 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_S49_N PF08496.5 XP_011274562.1 - 1.1 8.9 8.3 0.55 10.0 0.8 2.5 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Ribosomal_L12 PF00542.14 XP_011274563.1 - 1.9e-18 66.2 7.8 1.9e-18 66.2 5.4 2.6 3 0 0 3 3 3 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_60s PF00428.14 XP_011274563.1 - 0.0022 18.3 8.1 0.0022 18.3 5.6 3.0 2 1 1 3 3 3 1 60s Acidic ribosomal protein Chisel PF15355.1 XP_011274563.1 - 0.077 13.0 0.3 0.19 11.7 0.2 1.6 1 0 0 1 1 1 0 Stretch-responsive small skeletal muscle X protein, Chisel Interferon PF00143.14 XP_011274564.1 - 0.0065 16.3 2.6 0.012 15.5 1.8 1.4 1 0 0 1 1 1 1 Interferon alpha/beta domain Pkinase PF00069.20 XP_011274565.1 - 5e-70 235.6 0.0 7e-70 235.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011274565.1 - 9.8e-39 132.9 0.0 1.8e-38 132.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 XP_011274565.1 - 3.3e-06 26.2 0.0 6.5e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like WaaY PF06176.6 XP_011274565.1 - 0.0061 15.8 0.2 0.0097 15.1 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) YrbL-PhoP_reg PF10707.4 XP_011274565.1 - 0.025 13.9 0.1 0.1 11.9 0.0 1.9 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Kdo PF06293.9 XP_011274565.1 - 0.03 13.3 0.0 0.052 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 XP_011274565.1 - 0.039 13.6 0.0 0.11 12.2 0.0 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family TFIIA PF03153.8 XP_011274565.1 - 0.4 10.5 14.4 0.51 10.1 10.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF605 PF04652.11 XP_011274565.1 - 0.59 9.4 11.2 0.83 8.9 7.8 1.2 1 0 0 1 1 1 0 Vta1 like DEAD PF00270.24 XP_011274566.1 - 3.1e-47 160.2 0.0 1.6e-45 154.6 0.0 2.7 2 1 0 2 2 2 1 DEAD/DEAH box helicase DBP10CT PF08147.7 XP_011274566.1 - 3.6e-22 77.9 4.5 3.6e-22 77.9 3.1 2.9 4 0 0 4 4 4 1 DBP10CT (NUC160) domain Helicase_C PF00271.26 XP_011274566.1 - 1e-21 76.5 0.0 3.1e-21 75.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Gly_transf_sug PF04488.10 XP_011274567.1 - 7.5e-12 45.5 0.5 2.8e-11 43.7 0.4 2.0 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif NTP_transf_2 PF01909.18 XP_011274568.1 - 8.6e-18 64.4 0.0 3.5e-17 62.4 0.0 2.1 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.14 XP_011274568.1 - 4e-15 55.4 0.1 1.3e-14 53.8 0.1 2.0 1 0 0 1 1 1 1 Cid1 family poly A polymerase DNA_pol_B_palm PF14792.1 XP_011274568.1 - 0.039 14.0 0.0 0.095 12.7 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase beta palm RF-1 PF00472.15 XP_011274569.1 - 2.7e-14 52.9 1.1 5e-14 52.0 0.7 1.4 1 1 0 1 1 1 1 RF-1 domain GSCFA PF08885.6 XP_011274569.1 - 0.04 13.4 0.6 0.054 13.0 0.4 1.1 1 0 0 1 1 1 0 GSCFA family Redoxin PF08534.5 XP_011274570.1 - 5.3e-26 90.9 0.0 7.2e-26 90.4 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 XP_011274570.1 - 2.7e-09 36.7 0.0 3.4e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family DCP1 PF06058.8 XP_011274571.1 - 2.3e-18 66.4 0.3 8.9e-18 64.5 0.2 1.9 1 1 0 1 1 1 1 Dcp1-like decapping family Spt20 PF12090.3 XP_011274572.1 - 4.7e-50 169.4 3.8 4.7e-50 169.4 2.7 3.1 3 1 0 3 3 3 1 Spt20 family C-term_anchor PF13461.1 XP_011274572.1 - 0.019 15.4 4.0 0.023 15.1 1.1 2.5 2 0 0 2 2 2 0 Cell-wall surface anchor repeat Vps26 PF03643.10 XP_011274573.1 - 5.5e-111 369.7 2.0 6.4e-111 369.5 1.4 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Rgp1 PF08737.5 XP_011274573.1 - 0.0035 16.4 2.2 0.14 11.2 0.4 2.7 3 0 0 3 3 3 2 Rgp1 Arrestin_N PF00339.24 XP_011274573.1 - 0.0077 16.0 1.2 1.7 8.4 0.5 3.0 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain CENP-F_leu_zip PF10473.4 XP_011274574.1 - 1.5 8.7 23.2 0.32 10.8 1.7 2.9 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Bud13 PF09736.4 XP_011274574.1 - 9.9 6.4 11.6 3.4 7.9 0.1 3.1 3 0 0 3 3 3 0 Pre-mRNA-splicing factor of RES complex SEN1_N PF12726.2 XP_011274575.1 - 3.9e-164 547.5 16.8 6.2e-164 546.9 11.6 1.3 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 XP_011274575.1 - 3.8e-70 236.1 2.7 3.8e-70 236.1 1.9 2.7 4 0 0 4 4 4 1 AAA domain AAA_12 PF13087.1 XP_011274575.1 - 1.4e-62 210.6 0.0 1.4e-62 210.6 0.0 2.8 4 0 0 4 4 4 1 AAA domain AAA_19 PF13245.1 XP_011274575.1 - 2.6e-12 46.3 0.0 7e-12 44.9 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 XP_011274575.1 - 4.6e-08 32.8 0.0 2.2e-05 24.1 0.0 2.8 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 XP_011274575.1 - 4.8e-05 22.9 0.1 0.17 11.4 0.0 3.6 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase T2SE PF00437.15 XP_011274575.1 - 0.0012 17.7 0.1 0.0027 16.6 0.1 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein DEAD PF00270.24 XP_011274575.1 - 0.018 14.5 3.9 0.045 13.2 0.0 2.8 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA PF00004.24 XP_011274575.1 - 0.093 12.9 5.8 0.12 12.5 0.7 3.4 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) DUF1900 PF08954.6 XP_011274576.1 - 2.4e-48 163.1 0.0 6.6e-48 161.6 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1900) WD40 PF00400.27 XP_011274576.1 - 4.8e-22 76.9 1.0 7.5e-07 28.8 0.0 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat DUF1899 PF08953.6 XP_011274576.1 - 5.6e-09 35.5 0.5 1.1e-08 34.5 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) Nup160 PF11715.3 XP_011274576.1 - 0.00075 17.7 0.2 0.0076 14.4 0.1 2.0 1 1 1 2 2 2 1 Nucleoporin Nup120/160 Mitofilin PF09731.4 XP_011274576.1 - 0.57 8.7 35.9 0.88 8.1 24.9 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Cut8_C PF08559.5 XP_011274577.1 - 4.5e-44 149.7 1.0 7.8e-44 148.9 0.7 1.4 1 0 0 1 1 1 1 Cut8 six-helix bundle Cut8_M PF14483.1 XP_011274577.1 - 2.2e-08 33.7 0.3 5.6e-08 32.4 0.2 1.8 1 0 0 1 1 1 1 Cut8 dimerisation domain FadR_C PF07840.7 XP_011274577.1 - 0.027 14.1 0.0 1.6 8.3 0.0 2.3 1 1 1 2 2 2 0 FadR C-terminal domain Bac_luciferase PF00296.15 XP_011274578.1 - 6.5e-57 192.9 0.0 9.2e-57 192.4 0.0 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase DAHP_synth_1 PF00793.15 XP_011274581.1 - 2.6e-05 23.0 0.0 0.00011 21.0 0.0 1.9 1 1 0 1 1 1 1 DAHP synthetase I family Med22 PF06179.7 XP_011274582.1 - 0.00065 19.6 25.4 0.095 12.7 17.6 3.9 1 1 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex DUF572 PF04502.8 XP_011274582.1 - 0.11 11.6 27.5 0.13 11.4 19.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) MIP-T3 PF10243.4 XP_011274582.1 - 0.65 8.4 38.5 0.8 8.0 26.7 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF966 PF06136.8 XP_011274582.1 - 4.7 6.5 22.4 5.9 6.1 15.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF2404 PF10296.4 XP_011274583.1 - 0.058 13.5 0.0 0.18 11.9 0.0 1.9 1 0 0 1 1 1 0 Putative integral membrane protein conserved region (DUF2404) Peptidase_M56 PF05569.6 XP_011274584.1 - 0.048 12.6 0.1 0.11 11.4 0.0 1.5 1 1 1 2 2 2 0 BlaR1 peptidase M56 Alba PF01918.16 XP_011274585.1 - 0.00018 21.0 1.8 0.0003 20.3 1.3 1.4 1 0 0 1 1 1 1 Alba GLYCAM-1 PF05242.6 XP_011274585.1 - 0.023 14.6 5.1 0.038 13.9 3.5 1.3 1 0 0 1 1 1 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) TraS PF10624.4 XP_011274585.1 - 0.078 12.5 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Plasmid conjugative transfer entry exclusion protein TraS Syntaxin-18_N PF10496.4 XP_011274585.1 - 0.5 10.2 5.5 1.2 8.9 3.8 1.7 1 1 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus Ndc1_Nup PF09531.5 XP_011274585.1 - 0.61 8.4 7.6 0.69 8.2 5.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Claudin_2 PF13903.1 XP_011274586.1 - 4.8 6.8 9.7 3.2 7.4 0.3 2.6 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction ORMDL PF04061.9 XP_011274587.1 - 4.8e-56 188.0 1.6 6e-56 187.7 1.1 1.1 1 0 0 1 1 1 1 ORMDL family RabGAP-TBC PF00566.13 XP_011274588.1 - 4.2e-42 144.0 8.3 4.2e-42 144.0 5.8 2.3 1 1 0 2 2 2 1 Rab-GTPase-TBC domain SusD-like_3 PF14322.1 XP_011274588.1 - 8.3 6.4 9.2 1.2 9.1 2.2 2.3 2 0 0 2 2 2 0 Starch-binding associating with outer membrane PQ-loop PF04193.9 XP_011274589.1 - 0.0047 16.4 10.9 0.059 12.9 1.7 3.2 2 1 1 3 3 3 2 PQ loop repeat ABC2_membrane_5 PF13346.1 XP_011274589.1 - 4.6 6.4 19.8 27 3.9 13.7 2.0 1 1 0 1 1 1 0 ABC-2 family transporter protein zf-C3HC4 PF00097.20 XP_011274590.1 - 1.8e-06 27.5 8.6 3.2e-06 26.7 6.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 XP_011274590.1 - 8.1e-06 25.4 5.9 1.5e-05 24.6 4.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 XP_011274590.1 - 1.3e-05 24.7 5.1 2.1e-05 24.1 3.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 XP_011274590.1 - 4.2e-05 23.2 6.5 6.8e-05 22.6 4.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 XP_011274590.1 - 4.7e-05 23.3 9.0 8.3e-05 22.5 6.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 XP_011274590.1 - 0.0084 15.9 8.4 0.049 13.5 5.8 2.1 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 XP_011274590.1 - 0.017 14.8 4.5 0.017 14.8 3.2 2.4 1 1 1 2 2 2 0 RING-type zinc-finger zf-MIZ PF02891.15 XP_011274590.1 - 0.057 12.9 5.4 0.12 11.9 3.8 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger FANCL_C PF11793.3 XP_011274590.1 - 0.26 11.2 3.2 0.6 10.1 2.2 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain adh_short PF00106.20 XP_011274591.1 - 8.9e-19 68.0 0.0 4.6e-18 65.7 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 XP_011274591.1 - 2.1e-09 37.5 0.0 2.8e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 XP_011274591.1 - 0.00046 19.8 0.0 0.82 9.3 0.0 2.2 2 0 0 2 2 2 2 KR domain RmlD_sub_bind PF04321.12 XP_011274591.1 - 0.13 11.0 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain Epimerase PF01370.16 XP_011274591.1 - 0.17 11.2 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family WGG PF10273.4 XP_011274592.1 - 7e-26 90.1 2.5 1.2e-25 89.4 1.8 1.4 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 DUF3245 PF11595.3 XP_011274592.1 - 0.011 16.0 0.5 0.021 15.1 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) Metallophos PF00149.23 XP_011274593.1 - 4.6e-40 137.1 0.3 7.3e-40 136.5 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Voldacs PF03517.8 XP_011274594.1 - 5.4e-11 42.4 0.8 1.2e-10 41.3 0.1 1.9 1 1 1 2 2 2 1 Regulator of volume decrease after cellular swelling NUMOD1 PF07453.8 XP_011274594.1 - 9.7 6.2 9.5 5.9 6.8 0.1 3.3 3 0 0 3 3 3 0 NUMOD1 domain RGS PF00615.14 XP_011274596.1 - 2.7e-07 30.7 4.9 8.5e-07 29.0 3.4 1.8 1 1 0 1 1 1 1 Regulator of G protein signaling domain SCF PF02404.10 XP_011274596.1 - 0.51 9.4 6.6 0.73 8.9 4.6 1.2 1 0 0 1 1 1 0 Stem cell factor bZIP_2 PF07716.10 XP_011274597.1 - 2.9e-10 39.8 8.6 2.9e-10 39.8 6.0 2.3 3 0 0 3 3 3 1 Basic region leucine zipper bZIP_1 PF00170.16 XP_011274597.1 - 0.0026 17.7 9.4 0.0026 17.7 6.5 2.7 2 0 0 2 2 2 1 bZIP transcription factor DUF4473 PF14747.1 XP_011274597.1 - 0.053 13.7 0.0 0.19 11.9 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) 4HBT PF03061.17 XP_011274598.1 - 0.01 15.9 0.2 0.65 10.1 0.0 2.5 2 0 0 2 2 2 0 Thioesterase superfamily He_PIG PF05345.7 XP_011274599.1 - 3.2e-14 52.6 7.8 7.9e-06 25.7 0.0 5.1 4 0 0 4 4 4 3 Putative Ig domain SKG6 PF08693.5 XP_011274599.1 - 1e-07 31.1 0.2 2.4e-07 29.9 0.1 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM154 PF15102.1 XP_011274599.1 - 6e-05 22.7 0.2 6e-05 22.7 0.1 2.4 2 0 0 2 2 2 1 TMEM154 protein family Mid2 PF04478.7 XP_011274599.1 - 8.9e-05 21.9 0.1 8.9e-05 21.9 0.1 2.2 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor DUF4448 PF14610.1 XP_011274599.1 - 0.00038 20.0 0.9 0.0012 18.3 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) DUF1517 PF07466.6 XP_011274599.1 - 0.001 18.1 2.3 0.001 18.1 1.6 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1517) Shisa PF13908.1 XP_011274599.1 - 0.026 14.6 0.0 0.026 14.6 0.0 2.5 2 1 0 2 2 2 0 Wnt and FGF inhibitory regulator EphA2_TM PF14575.1 XP_011274599.1 - 0.03 14.7 0.0 0.083 13.2 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain MLANA PF14991.1 XP_011274599.1 - 0.041 13.9 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 Protein melan-A End3 PF12761.2 XP_011274600.1 - 7.4e-62 208.4 13.2 1.1e-61 207.8 9.2 1.3 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.2 XP_011274600.1 - 2.3e-55 184.7 0.1 2.3e-52 175.1 0.2 2.5 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 XP_011274600.1 - 3.6e-05 22.7 0.2 0.00014 20.9 0.2 2.1 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.1 XP_011274600.1 - 0.00057 19.4 0.1 0.0013 18.3 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 XP_011274600.1 - 0.016 15.0 0.3 0.15 11.9 0.1 2.8 2 0 0 2 2 2 0 EF-hand domain EF-hand_7 PF13499.1 XP_011274600.1 - 0.047 13.8 2.6 0.065 13.3 0.1 2.6 4 0 0 4 4 4 0 EF-hand domain pair Erp_C PF06780.6 XP_011274600.1 - 0.17 11.7 9.5 0.41 10.4 6.6 1.8 1 0 0 1 1 1 0 Erp protein C-terminus DUF948 PF06103.6 XP_011274600.1 - 2.4 8.0 6.0 2.1 8.2 1.9 2.4 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) AAA_23 PF13476.1 XP_011274600.1 - 2.7 8.2 24.6 6.6 6.9 17.1 1.8 1 1 0 1 1 1 0 AAA domain DUF641 PF04859.7 XP_011274600.1 - 4.6 7.0 12.6 0.92 9.2 5.0 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) TBPIP PF07106.8 XP_011274600.1 - 9 5.8 18.3 0.21 11.0 4.9 2.6 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Aldedh PF00171.17 XP_011274601.1 - 5.2e-168 559.1 0.0 7.5e-168 558.6 0.0 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Porin_3 PF01459.17 XP_011274601.1 - 7.5e-63 212.3 1.3 1e-62 211.9 0.9 1.2 1 0 0 1 1 1 1 Eukaryotic porin Aminotran_1_2 PF00155.16 XP_011274603.1 - 3e-57 194.2 0.0 3.4e-57 194.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 XP_011274603.1 - 0.011 14.0 0.0 0.018 13.3 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Alliinase_C PF04864.8 XP_011274603.1 - 0.045 12.3 0.0 0.063 11.9 0.0 1.1 1 0 0 1 1 1 0 Allinase Sugar_tr PF00083.19 XP_011274604.1 - 9.6e-109 363.9 25.4 1.1e-108 363.7 17.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 XP_011274604.1 - 2.6e-26 92.2 24.7 2.6e-26 92.2 17.1 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Herpes_BMRF2 PF04633.7 XP_011274604.1 - 0.0004 19.4 0.7 0.00086 18.3 0.5 1.5 1 0 0 1 1 1 1 Herpesvirus BMRF2 protein Phage_holin_2 PF04550.7 XP_011274604.1 - 0.062 13.4 0.2 0.14 12.2 0.2 1.5 1 0 0 1 1 1 0 Phage holin family 2 HPP PF04982.8 XP_011274605.1 - 2.4e-36 124.1 3.7 4e-36 123.4 2.6 1.3 1 0 0 1 1 1 1 HPP family Y_phosphatase2 PF03162.8 XP_011274606.1 - 6.3e-52 175.2 0.0 7.3e-52 175.0 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 XP_011274606.1 - 0.00012 22.3 0.0 0.00028 21.1 0.0 1.5 1 1 1 2 2 2 1 Tyrosine phosphatase family TBCA PF02970.11 XP_011274607.1 - 0.072 13.1 0.5 0.19 11.8 0.3 1.6 1 0 0 1 1 1 0 Tubulin binding cofactor A Glycophorin_A PF01102.13 XP_011274608.1 - 0.2 11.4 4.4 0.056 13.2 0.4 2.0 2 0 0 2 2 2 0 Glycophorin A Ras PF00071.17 XP_011274609.1 - 6.4e-58 194.7 0.0 7.4e-58 194.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 XP_011274609.1 - 4.2e-16 59.5 0.0 5.6e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 XP_011274609.1 - 2.5e-10 39.8 0.0 3.5e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 XP_011274609.1 - 0.0014 17.7 0.0 0.0016 17.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 XP_011274609.1 - 0.0023 17.8 0.0 0.0032 17.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 XP_011274609.1 - 0.0035 16.7 0.0 0.21 10.9 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 XP_011274609.1 - 0.015 14.5 0.0 0.021 14.0 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.22 XP_011274609.1 - 0.047 13.9 0.0 0.087 13.1 0.0 1.6 2 0 0 2 2 2 0 ABC transporter RRM_1 PF00076.17 XP_011274610.1 - 0.00015 21.3 0.0 0.00039 20.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 XP_011274610.1 - 0.014 15.3 0.1 0.053 13.5 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF1774 PF08611.5 XP_011274611.1 - 2.8e-32 110.7 2.4 2.8e-32 110.7 1.6 2.8 3 1 0 3 3 3 1 Fungal protein of unknown function (DUF1774) Tho2 PF11262.3 XP_011274612.1 - 8.9e-50 169.4 12.3 8.9e-50 169.4 8.5 3.7 5 1 0 5 5 5 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 XP_011274612.1 - 4.6e-27 93.6 0.4 2e-26 91.5 0.1 2.3 2 0 0 2 2 2 1 Transcription- and export-related complex subunit DUF106 PF01956.11 XP_011274612.1 - 3.8 7.0 11.6 0.023 14.2 0.5 2.7 2 0 0 2 2 2 0 Integral membrane protein DUF106 Pkinase PF00069.20 XP_011274613.1 - 2.6e-38 131.6 0.0 1.7e-23 83.1 0.0 2.6 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011274613.1 - 2.2e-22 79.3 0.0 1e-13 50.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 XP_011274613.1 - 0.024 13.6 0.0 4.2 6.2 0.0 2.2 2 0 0 2 2 2 0 Kinase-like SpoIISB_antitox PF14185.1 XP_011274613.1 - 0.45 10.3 7.3 8.9 6.1 0.6 3.6 3 1 0 3 3 3 0 Antitoxin SpoIISB, type II toxin-antitoxin system UcrQ PF02939.11 XP_011274614.1 - 1.4e-30 104.9 0.6 1.6e-30 104.7 0.4 1.0 1 0 0 1 1 1 1 UcrQ family DUF2741 PF10890.3 XP_011274614.1 - 0.07 13.2 0.0 0.081 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2741) polyprenyl_synt PF00348.12 XP_011274615.1 - 4e-81 271.7 0.0 4.6e-81 271.4 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase Ebp2 PF05890.7 XP_011274616.1 - 3.1e-88 295.6 28.6 3.1e-88 295.6 19.9 2.6 1 1 1 2 2 2 1 Eukaryotic rRNA processing protein EBP2 DUF1517 PF07466.6 XP_011274616.1 - 0.29 10.0 3.6 0.68 8.8 2.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) GTP_EFTU PF00009.22 XP_011274617.1 - 3.5e-33 114.6 0.0 1.2e-32 112.8 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 XP_011274617.1 - 1.5e-21 76.1 0.0 3.8e-21 74.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 XP_011274617.1 - 2e-16 59.6 0.0 5.4e-16 58.2 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 XP_011274617.1 - 3.3e-10 39.9 0.2 1.1e-09 38.2 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.1 XP_011274617.1 - 0.0006 19.6 0.0 0.0021 17.8 0.0 2.0 1 0 0 1 1 1 1 Elongation Factor G, domain II SRPRB PF09439.5 XP_011274617.1 - 0.017 14.3 2.3 0.77 8.9 0.1 3.3 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit Miro PF08477.8 XP_011274617.1 - 0.022 15.2 0.5 0.072 13.5 0.3 2.0 1 1 0 1 1 1 0 Miro-like protein Dynamin_N PF00350.18 XP_011274617.1 - 0.11 12.3 5.1 4.6 7.0 0.3 2.6 1 1 1 2 2 2 0 Dynamin family AA_permease_2 PF13520.1 XP_011274618.1 - 3.8e-44 150.9 53.1 4.9e-44 150.5 36.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 XP_011274618.1 - 3.8e-44 150.8 46.6 4.9e-44 150.4 32.3 1.0 1 0 0 1 1 1 1 Amino acid permease Gram_pos_anchor PF00746.16 XP_011274618.1 - 0.062 13.1 0.0 0.062 13.1 0.0 4.1 5 0 0 5 5 5 0 Gram positive anchor DIOX_N PF14226.1 XP_011274619.1 - 1.9e-18 67.0 0.2 3e-18 66.4 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 XP_011274619.1 - 7.5e-16 58.2 0.0 2.9e-15 56.3 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DEAD PF00270.24 XP_011274620.1 - 2e-33 115.2 0.0 3.8e-33 114.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 XP_011274620.1 - 2.9e-22 78.2 0.0 1.1e-21 76.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 XP_011274620.1 - 1.6e-06 28.1 0.0 3.4e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 XP_011274620.1 - 0.00021 20.4 0.0 0.00039 19.5 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit Ribosomal_S13 PF00416.17 XP_011274621.1 - 0.14 12.6 1.1 5.6 7.4 0.0 3.0 2 0 0 2 2 2 0 Ribosomal protein S13/S18 ESSS PF10183.4 XP_011274622.1 - 0.15 12.5 0.0 0.22 11.9 0.0 1.3 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Ribosomal_S9 PF00380.14 XP_011274624.1 - 9.1e-40 135.6 0.4 1e-39 135.4 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ribosomal_L13e PF01294.13 XP_011274625.1 - 3.8e-67 225.2 6.2 5.9e-67 224.5 4.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L13e zf-H2C2_2 PF13465.1 XP_011274625.1 - 0.037 14.3 1.0 0.56 10.5 0.0 2.3 2 0 0 2 2 2 0 Zinc-finger double domain 4HBT_3 PF13622.1 XP_011274625.1 - 0.13 11.9 2.0 0.73 9.5 1.1 2.1 1 1 0 1 1 1 0 Thioesterase-like superfamily Ribosomal_60s PF00428.14 XP_011274626.1 - 8e-24 83.8 13.7 9.6e-24 83.5 9.5 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein COPI_assoc PF08507.5 XP_011274628.1 - 0.24 11.1 7.9 0.77 9.4 5.5 1.9 1 0 0 1 1 1 0 COPI associated protein Neurensin PF14927.1 XP_011274628.1 - 0.43 9.9 1.7 2.6 7.4 1.3 2.1 2 0 0 2 2 2 0 Neurensin bZIP_2 PF07716.10 XP_011274629.1 - 2e-06 27.5 7.8 2.1e-06 27.4 4.4 1.8 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 XP_011274629.1 - 2.6e-06 27.2 5.2 3.2e-06 26.9 2.6 1.8 1 1 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 XP_011274629.1 - 0.024 14.8 2.6 0.044 14.0 1.8 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor ING PF12998.2 XP_011274629.1 - 0.28 11.4 3.7 8.7 6.6 0.2 2.4 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DNA_ligase_A_M PF01068.16 XP_011274630.1 - 2.2e-49 167.5 0.2 4.8e-49 166.4 0.1 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 XP_011274630.1 - 4.6e-22 78.6 0.1 9.5e-22 77.6 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus BRCT PF00533.21 XP_011274630.1 - 5.5e-08 32.8 4.2 6.3e-05 23.0 0.6 3.0 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain DNA_ligase_A_C PF04679.10 XP_011274630.1 - 1.4e-07 31.8 0.0 3.8e-07 30.4 0.0 1.8 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RVP_2 PF08284.6 XP_011274630.1 - 0.056 13.3 0.2 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF367 PF04034.8 XP_011274631.1 - 3e-51 172.3 0.3 4.6e-51 171.7 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF367) VPS9 PF02204.13 XP_011274632.1 - 4.3e-12 45.9 0.4 1.6e-11 44.1 0.3 2.1 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_5 PF13857.1 XP_011274632.1 - 8.7e-06 25.8 0.1 0.00033 20.7 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.25 XP_011274632.1 - 9.8e-06 25.1 0.1 0.54 10.1 0.0 4.6 5 1 0 5 5 5 2 Ankyrin repeat Ank_2 PF12796.2 XP_011274632.1 - 3.3e-05 24.1 0.0 0.034 14.4 0.0 3.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 XP_011274632.1 - 0.00088 19.2 0.3 12 6.5 0.0 5.6 6 0 0 6 6 6 1 Ankyrin repeat Ank_4 PF13637.1 XP_011274632.1 - 0.021 15.3 0.4 20 5.8 0.0 4.5 4 0 0 4 4 4 0 Ankyrin repeats (many copies) DUF2346 PF09803.4 XP_011274632.1 - 0.048 13.5 0.5 0.25 11.2 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2346) TPR_11 PF13414.1 XP_011274633.1 - 1.2e-24 85.7 9.3 1.6e-18 66.1 1.1 2.7 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 XP_011274633.1 - 1.9e-15 55.4 6.9 0.00017 21.2 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 XP_011274633.1 - 7.1e-15 53.9 6.4 6.2e-05 22.4 0.5 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 XP_011274633.1 - 4.8e-10 39.8 9.2 8.7e-06 26.2 0.3 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 XP_011274633.1 - 1.8e-08 33.9 3.7 0.00081 19.4 0.2 3.4 4 0 0 4 4 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 XP_011274633.1 - 5.3e-08 32.8 1.2 0.13 13.0 0.1 3.8 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 XP_011274633.1 - 6.9e-07 29.5 3.0 0.007 16.6 0.4 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat BTAD PF03704.12 XP_011274633.1 - 1.1e-05 25.8 2.8 0.00043 20.5 0.1 2.7 1 1 2 3 3 3 1 Bacterial transcriptional activator domain TPR_12 PF13424.1 XP_011274633.1 - 4.4e-05 23.3 4.4 0.0002 21.2 0.9 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 XP_011274633.1 - 6.2e-05 22.7 0.7 0.0075 16.1 0.1 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 XP_011274633.1 - 0.0012 18.5 0.6 6 6.9 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 XP_011274633.1 - 0.026 14.2 7.5 1 9.3 0.5 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4368 PF14287.1 XP_011274633.1 - 0.045 13.5 0.0 0.09 12.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4368) Rho_N PF07498.7 XP_011274633.1 - 0.11 12.2 1.5 1.3 8.8 0.7 2.9 3 0 0 3 3 3 0 Rho termination factor, N-terminal domain TPR_6 PF13174.1 XP_011274633.1 - 0.18 12.3 3.4 12 6.5 0.2 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat XPC-binding PF09280.6 XP_011274633.1 - 0.39 10.2 4.9 0.91 9.0 3.4 1.6 1 0 0 1 1 1 0 XPC-binding domain Colicin_immun PF09204.5 XP_011274633.1 - 1.6 8.8 4.3 4.7 7.3 1.1 2.7 2 1 0 2 2 2 0 Bacterial self-protective colicin-like immunity WD40 PF00400.27 XP_011274634.1 - 1.9e-24 84.5 0.8 9.6e-08 31.6 0.0 5.5 6 0 0 6 6 6 4 WD domain, G-beta repeat zf-RING_2 PF13639.1 XP_011274634.1 - 0.00012 21.7 3.6 0.00012 21.7 2.5 1.7 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 XP_011274634.1 - 0.0025 17.8 3.9 0.0057 16.7 2.7 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 XP_011274634.1 - 0.005 16.8 4.1 0.005 16.8 2.8 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.17 XP_011274634.1 - 0.024 14.3 5.7 0.71 9.6 2.6 2.4 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4 PF00097.20 XP_011274634.1 - 0.025 14.2 5.9 0.031 13.9 0.8 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C2H2_jaz PF12171.3 XP_011274634.1 - 0.11 12.6 2.7 0.2 11.8 0.2 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Rpr2 PF04032.11 XP_011274634.1 - 0.92 9.4 7.3 7.5 6.4 5.0 2.7 2 1 1 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Abhydrolase_5 PF12695.2 XP_011274635.1 - 1e-21 77.1 0.0 1.4e-21 76.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 XP_011274635.1 - 7.2e-16 58.7 0.0 4.5e-14 52.8 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 XP_011274635.1 - 5.2e-09 36.0 0.0 1.5e-05 24.6 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 XP_011274635.1 - 1.4e-06 27.9 0.0 4.7e-06 26.2 0.0 1.7 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.6 XP_011274635.1 - 5.9e-06 26.1 0.0 0.0013 18.4 0.0 2.2 1 1 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.8 XP_011274635.1 - 0.00011 21.7 0.0 0.00018 21.0 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Hydrolase_4 PF12146.3 XP_011274635.1 - 0.00014 21.6 0.0 0.00025 20.8 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase AXE1 PF05448.7 XP_011274635.1 - 0.0007 18.1 0.0 0.038 12.5 0.0 2.8 2 1 1 3 3 3 1 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.11 XP_011274635.1 - 0.00083 18.8 0.0 0.056 12.8 0.0 2.1 1 1 1 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 XP_011274635.1 - 0.0024 17.1 0.0 0.016 14.4 0.0 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.15 XP_011274635.1 - 0.016 14.6 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Putative esterase LIP PF03583.9 XP_011274635.1 - 0.02 14.0 0.0 0.077 12.1 0.0 1.9 2 0 0 2 2 2 0 Secretory lipase Lipase_3 PF01764.20 XP_011274635.1 - 0.035 13.7 0.0 0.061 12.9 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DLH PF01738.13 XP_011274635.1 - 0.04 13.2 0.0 0.41 9.8 0.0 2.2 1 1 0 1 1 1 0 Dienelactone hydrolase family DUF818 PF05677.7 XP_011274635.1 - 0.04 12.6 0.4 0.085 11.5 0.0 1.5 1 1 1 2 2 2 0 Chlamydia CHLPS protein (DUF818) Acyl_transf_2 PF02273.10 XP_011274635.1 - 0.11 11.4 0.1 0.33 9.9 0.0 1.7 2 0 0 2 2 2 0 Acyl transferase UPF0227 PF05728.7 XP_011274635.1 - 0.13 12.0 0.0 0.5 10.0 0.0 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0227) IF4E PF01652.13 XP_011274636.1 - 1.3e-56 190.7 0.8 1.6e-56 190.4 0.6 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Alpha-amylase PF00128.19 XP_011274638.1 - 4.9e-99 331.6 7.5 7.8e-99 331.0 5.2 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Na_Ca_ex PF01699.19 XP_011274640.1 - 1.5e-28 99.1 28.1 3.5e-18 65.5 7.7 4.9 5 1 1 6 6 6 2 Sodium/calcium exchanger protein DUF307 PF03733.8 XP_011274640.1 - 3.6e-10 40.1 13.1 3.6e-10 40.1 9.1 4.0 3 0 0 3 3 3 1 Domain of unknown function (DUF307) zf-C4 PF00105.13 XP_011274640.1 - 0.14 12.4 0.4 0.45 10.7 0.0 2.1 2 0 0 2 2 2 0 Zinc finger, C4 type (two domains) Aminotran_3 PF00202.16 XP_011274641.1 - 4e-100 334.9 0.0 5.4e-100 334.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 XP_011274641.1 - 7.6e-06 25.1 0.0 0.00027 19.9 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II PucR PF07905.6 XP_011274641.1 - 0.038 13.5 0.0 0.1 12.2 0.0 1.7 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family SpoIIID PF12116.3 XP_011274642.1 - 0.12 12.2 2.5 0.15 11.9 1.0 1.8 2 0 0 2 2 2 0 Stage III sporulation protein D MFS_1 PF07690.11 XP_011274643.1 - 2.8e-32 111.8 17.5 2.8e-32 111.8 12.1 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 XP_011274643.1 - 2.9e-32 111.8 18.0 1.8e-31 109.2 12.5 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter DUF1675 PF07897.6 XP_011274643.1 - 0.54 10.0 3.0 1.6 8.5 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1675) Sugar_tr PF00083.19 XP_011274644.1 - 9.6e-39 133.2 17.3 6.9e-38 130.3 12.0 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 XP_011274644.1 - 6.7e-31 107.2 20.2 2.6e-30 105.3 13.8 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Pkinase PF00069.20 XP_011274645.1 - 1.8e-76 256.7 0.0 2.1e-76 256.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011274645.1 - 8.4e-33 113.5 0.0 1.1e-32 113.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 XP_011274645.1 - 0.00099 18.1 0.0 0.0019 17.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 XP_011274645.1 - 0.0026 16.8 0.3 0.0047 16.0 0.2 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 XP_011274645.1 - 0.018 13.8 0.1 0.026 13.3 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 XP_011274645.1 - 0.021 14.5 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family YukC PF10140.4 XP_011274645.1 - 0.038 12.5 0.1 0.049 12.1 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Ribosomal_L29 PF00831.18 XP_011274646.1 - 6.6 6.5 17.4 4.7 6.9 0.6 4.3 4 0 0 4 4 4 0 Ribosomal L29 protein WSC PF01822.14 XP_011274647.1 - 1.2e-10 41.1 14.5 1.2e-10 41.1 10.1 3.8 3 1 0 3 3 3 1 WSC domain FAM196 PF15265.1 XP_011274647.1 - 2.1 7.4 34.4 2.6 7.1 23.8 1.2 1 0 0 1 1 1 0 FAM196 family Otopetrin PF03189.8 XP_011274647.1 - 7.5 5.4 18.0 26 3.6 12.5 1.8 1 1 0 1 1 1 0 Otopetrin zf-C2H2 PF00096.21 XP_011274648.1 - 6.2e-06 26.2 2.3 6.2e-06 26.2 1.6 4.0 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 XP_011274648.1 - 0.00076 19.6 3.5 0.00076 19.6 2.4 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 XP_011274648.1 - 0.0017 18.4 0.4 0.0017 18.4 0.3 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 XP_011274648.1 - 0.014 15.6 0.7 0.014 15.6 0.5 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 XP_011274648.1 - 1.5 8.9 8.6 0.82 9.8 3.3 2.7 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 XP_011274648.1 - 6.8 7.0 8.5 0.24 11.6 0.4 2.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Pkinase PF00069.20 XP_011274649.1 - 4.8e-05 22.6 5.4 0.00016 20.9 3.7 1.9 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 XP_011274649.1 - 0.011 14.6 0.0 0.024 13.6 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Pkinase_Tyr PF07714.12 XP_011274649.1 - 0.039 13.0 0.4 0.088 11.8 0.3 1.7 1 1 0 1 1 1 0 Protein tyrosine kinase GDPD PF03009.12 XP_011274649.1 - 0.048 13.1 2.3 0.22 11.0 1.4 1.8 1 1 1 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family Pkinase PF00069.20 XP_011274650.1 - 1.8e-05 24.0 0.5 3.8e-05 22.9 0.4 1.5 1 0 0 1 1 1 1 Protein kinase domain Tox-MPTase5 PF15641.1 XP_011274650.1 - 0.07 13.1 0.0 0.18 11.7 0.0 1.7 1 1 0 1 1 1 0 Metallopeptidase toxin 5 LRR_7 PF13504.1 XP_011274651.1 - 1.9e-05 24.1 16.6 2.5 8.6 0.1 7.2 6 0 0 6 6 6 3 Leucine rich repeat LRR_8 PF13855.1 XP_011274651.1 - 0.00027 20.6 3.9 0.00027 20.6 2.7 5.1 5 1 0 5 5 5 1 Leucine rich repeat LRR_4 PF12799.2 XP_011274651.1 - 0.0023 17.5 31.8 0.0075 15.8 2.5 4.9 4 2 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 XP_011274651.1 - 0.021 14.8 26.5 2.2 8.6 0.4 7.2 7 1 0 7 7 7 0 Leucine Rich Repeat LRR_6 PF13516.1 XP_011274651.1 - 0.026 14.5 24.3 1.5 9.0 0.2 7.3 7 0 0 7 7 7 0 Leucine Rich repeat Oxidored_FMN PF00724.15 XP_011274652.1 - 1.7e-115 385.6 0.0 2e-115 385.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Oxidored_FMN PF00724.15 XP_011274653.1 - 1.4e-110 369.4 0.0 1.7e-110 369.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Oxidored_FMN PF00724.15 XP_011274654.1 - 2.8e-108 361.9 0.0 3.2e-108 361.7 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family CLTH PF10607.4 XP_011274655.1 - 3e-24 85.3 15.0 5.5e-24 84.5 10.3 1.5 1 1 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 XP_011274655.1 - 3.8e-05 23.2 0.3 9.6e-05 22.0 0.2 1.8 1 0 0 1 1 1 1 LisH VacA PF02691.10 XP_011274656.1 - 0.014 13.0 0.1 0.017 12.7 0.1 1.1 1 0 0 1 1 1 0 Vacuolating cyotoxin SRP1_TIP1 PF00660.12 XP_011274657.1 - 5e-22 77.6 0.0 7.8e-22 77.0 0.0 1.2 1 0 0 1 1 1 1 Seripauperin and TIP1 family SRP1_TIP1 PF00660.12 XP_011274658.1 - 7e-19 67.5 0.5 1.2e-18 66.8 0.3 1.4 1 0 0 1 1 1 1 Seripauperin and TIP1 family Bul1_C PF04426.7 XP_011274658.1 - 0.1 11.7 0.1 0.13 11.3 0.1 1.1 1 0 0 1 1 1 0 Bul1 C terminus DUF605 PF04652.11 XP_011274658.1 - 0.38 10.0 8.2 0.43 9.9 5.7 1.1 1 0 0 1 1 1 0 Vta1 like DUF3275 PF11679.3 XP_011274658.1 - 0.61 9.6 2.4 0.79 9.3 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) PRCC PF10253.4 XP_011274658.1 - 5.1 7.7 7.9 8.4 7.0 5.5 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting SRP1_TIP1 PF00660.12 XP_011274659.1 - 0.00017 21.3 0.2 0.00032 20.4 0.1 1.4 1 0 0 1 1 1 1 Seripauperin and TIP1 family Polyoma_lg_T_C PF06431.6 XP_011274659.1 - 0.14 10.8 3.2 0.097 11.3 1.2 1.4 2 0 0 2 2 2 0 Polyomavirus large T antigen C-terminus Macoilin PF09726.4 XP_011274659.1 - 0.5 8.5 12.5 0.51 8.5 8.7 1.1 1 0 0 1 1 1 0 Transmembrane protein SSP160 PF06933.6 XP_011274659.1 - 2.9 5.7 22.8 3.3 5.5 15.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 REC114-like PF15165.1 XP_011274660.1 - 0.0056 16.4 2.5 0.0081 15.9 1.7 1.4 1 0 0 1 1 1 1 Meiotic recombination protein REC114-like Viral_cys_rich PF08008.7 XP_011274660.1 - 0.017 14.6 0.2 0.046 13.2 0.1 1.8 1 0 0 1 1 1 0 Viral cysteine rich AA_permease_2 PF13520.1 XP_011274661.1 - 2.9e-63 213.9 51.2 3.6e-63 213.5 35.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 XP_011274661.1 - 2e-13 49.5 42.2 3.1e-13 48.9 29.2 1.2 1 0 0 1 1 1 1 Amino acid permease OppC_N PF12911.2 XP_011274661.1 - 0.011 15.0 0.2 0.011 15.0 0.1 3.8 4 0 0 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C RIC1 PF07064.8 XP_011274662.1 - 9.1e-19 67.9 0.4 1.7e-18 67.0 0.3 1.4 1 0 0 1 1 1 1 RIC1 tRNA_Me_trans PF03054.11 XP_011274663.1 - 4.8e-115 383.9 0.0 5.5e-115 383.7 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase NAD_synthase PF02540.12 XP_011274663.1 - 0.013 14.3 0.0 0.026 13.4 0.0 1.4 2 0 0 2 2 2 0 NAD synthase ING PF12998.2 XP_011274665.1 - 0.019 15.2 11.6 1.5 9.1 0.4 3.1 1 1 2 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding DUF2316 PF10078.4 XP_011274665.1 - 0.028 14.3 4.8 1.6 8.7 0.1 2.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) Fib_alpha PF08702.5 XP_011274665.1 - 1.1 9.3 14.2 0.12 12.5 5.1 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family LOH1CR12 PF10158.4 XP_011274665.1 - 1.6 8.5 12.7 0.46 10.2 3.2 2.5 1 1 2 3 3 3 0 Tumour suppressor protein DASH_Dad3 PF08656.5 XP_011274665.1 - 4.1 7.1 12.1 7.2 6.3 2.7 3.2 1 1 2 3 3 3 0 DASH complex subunit Dad3 DASH_Hsk3 PF08227.6 XP_011274665.1 - 4.6 7.5 5.9 10 6.4 0.6 2.9 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like DUF1664 PF07889.7 XP_011274665.1 - 5.3 6.8 7.6 7.7 6.3 0.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Cofilin_ADF PF00241.15 XP_011274666.1 - 6.6e-41 139.1 0.4 7.3e-41 139.0 0.3 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein HTH_Tnp_Tc5 PF03221.11 XP_011274667.1 - 4.8e-09 35.8 0.4 1.7e-08 34.1 0.1 2.0 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain BrkDBD PF09607.5 XP_011274667.1 - 0.082 12.4 0.1 0.18 11.3 0.1 1.6 1 0 0 1 1 1 0 Brinker DNA-binding domain ParB PF08775.5 XP_011274667.1 - 0.087 13.1 4.8 0.15 12.4 3.3 1.3 1 0 0 1 1 1 0 ParB family CENP-B_N PF04218.8 XP_011274667.1 - 0.098 12.1 0.3 0.38 10.2 0.2 2.0 1 1 0 1 1 1 0 CENP-B N-terminal DNA-binding domain FlaG PF03646.10 XP_011274667.1 - 0.18 11.9 2.5 0.29 11.2 1.6 1.5 1 1 0 1 1 1 0 FlaG protein Band_3_cyto PF07565.8 XP_011274667.1 - 1.2 8.5 5.1 1.5 8.2 3.5 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain HSF_DNA-bind PF00447.12 XP_011274668.1 - 7.3e-35 119.2 3.2 7.3e-35 119.2 2.2 2.9 2 0 0 2 2 2 1 HSF-type DNA-binding IncA PF04156.9 XP_011274668.1 - 0.04 13.5 22.2 0.5 9.9 9.5 2.4 2 0 0 2 2 2 0 IncA protein PMC2NT PF08066.7 XP_011274668.1 - 1.3 9.3 12.5 0.61 10.4 0.2 2.9 2 0 0 2 2 2 0 PMC2NT (NUC016) domain FAD-oxidase_C PF02913.14 XP_011274669.1 - 5e-52 176.6 0.0 6.4e-52 176.3 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 XP_011274669.1 - 4.7e-34 116.8 0.0 8e-34 116.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_binding_5 PF00941.16 XP_011274669.1 - 0.0033 16.8 0.0 0.0075 15.7 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Romo1 PF10247.4 XP_011274669.1 - 1.2 9.4 9.9 4.7 7.4 0.0 3.2 3 0 0 3 3 3 0 Reactive mitochondrial oxygen species modulator 1 FTR1 PF03239.9 XP_011274670.1 - 8.6e-94 313.9 8.6 1e-93 313.6 6.0 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family PrgI PF12666.2 XP_011274670.1 - 3.2 7.9 16.8 0.084 13.0 0.7 3.6 4 0 0 4 4 4 0 PrgI family protein FTR1 PF03239.9 XP_011274671.1 - 1.2e-97 326.6 7.3 1.4e-97 326.3 5.1 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family FAD_binding_4 PF01565.18 XP_011274671.1 - 0.065 12.6 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain Bacteriocin_IIc PF10439.4 XP_011274671.1 - 1.6 8.9 5.9 3.3 7.9 0.3 2.4 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide DUF4164 PF13747.1 XP_011274672.1 - 0.1 12.7 4.2 0.46 10.6 1.3 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Enolase_N PF03952.11 XP_011274672.1 - 0.36 10.7 2.7 0.41 10.5 0.5 2.1 2 1 0 2 2 2 0 Enolase, N-terminal domain DUF3213 PF11491.3 XP_011274672.1 - 5.2 7.0 11.1 0.19 11.5 2.3 2.6 3 1 0 3 3 3 0 Protein of unknown function (DUF3213) Aa_trans PF01490.13 XP_011274673.1 - 3.3e-56 190.5 40.3 4e-56 190.2 27.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 XP_011274673.1 - 4.9e-05 22.3 18.5 4.9e-05 22.3 12.8 2.2 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family AA_permease_2 PF13520.1 XP_011274673.1 - 0.0001 20.9 25.7 0.0001 20.9 17.8 2.1 2 0 0 2 2 2 1 Amino acid permease Rad21_Rec8_N PF04825.8 XP_011274674.1 - 1.1e-24 86.5 0.1 2.6e-24 85.2 0.1 1.6 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Pil1 PF13805.1 XP_011274675.1 - 6e-155 514.2 0.6 7.2e-155 513.9 0.4 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 DUF3590 PF12148.3 XP_011274675.1 - 0.066 12.8 0.1 0.15 11.7 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3590) PCP_red PF08369.5 XP_011274675.1 - 0.19 11.5 2.9 5.8 6.8 0.0 3.0 3 0 0 3 3 3 0 Proto-chlorophyllide reductase 57 kD subunit Hat1_N PF10394.4 XP_011274676.1 - 1.2e-30 106.7 4.2 2.6e-30 105.6 2.9 1.6 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_7 PF13508.1 XP_011274676.1 - 0.055 13.6 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain EAP30 PF04157.11 XP_011274677.1 - 3.5e-33 114.6 0.0 3.5e-33 114.6 0.0 1.8 2 0 0 2 2 2 1 EAP30/Vps36 family SPX PF03105.14 XP_011274677.1 - 8.5e-17 61.8 26.7 8.5e-17 61.8 18.5 2.5 2 1 0 2 2 2 1 SPX domain zf-C3HC4_3 PF13920.1 XP_011274677.1 - 3.4e-08 33.0 7.8 5.1e-08 32.4 5.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 XP_011274677.1 - 3.5e-07 29.7 12.3 7.5e-07 28.7 8.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 XP_011274677.1 - 5.8e-07 29.4 12.9 1.1e-06 28.5 9.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 XP_011274677.1 - 7.8e-07 28.8 10.8 1.6e-06 27.8 7.5 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 XP_011274677.1 - 8.5e-07 28.7 10.3 1.4e-06 28.0 7.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 XP_011274677.1 - 9.1e-06 25.3 9.5 1.6e-05 24.5 6.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain DUF4116 PF13475.1 XP_011274677.1 - 0.0017 17.7 1.6 0.021 14.3 0.1 3.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4116) zf-RING_UBOX PF13445.1 XP_011274677.1 - 0.043 13.5 10.5 0.18 11.5 7.3 2.2 1 0 0 1 1 1 0 RING-type zinc-finger PTPS PF01242.14 XP_011274677.1 - 0.081 12.6 0.8 13 5.5 0.0 2.7 2 0 0 2 2 2 0 6-pyruvoyl tetrahydropterin synthase zf-P11 PF03854.9 XP_011274677.1 - 0.14 11.6 7.2 4.6 6.8 5.3 2.4 1 1 1 2 2 2 0 P-11 zinc finger zf-rbx1 PF12678.2 XP_011274677.1 - 0.44 10.6 7.2 1.1 9.4 5.0 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger Prok-RING_4 PF14447.1 XP_011274677.1 - 0.83 9.2 5.0 2.2 7.8 3.4 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 XP_011274677.1 - 3.4 7.3 10.8 9.8 5.8 7.5 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain ThiF PF00899.16 XP_011274678.1 - 5.6e-09 35.9 0.0 2.3e-08 33.9 0.0 2.0 2 0 0 2 2 2 1 ThiF family Shikimate_dh_N PF08501.6 XP_011274679.1 - 5.6e-16 58.3 0.1 9.5e-15 54.4 0.0 2.6 3 0 0 3 3 3 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 XP_011274679.1 - 3.3e-07 30.4 0.0 5.4e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DHquinase_II PF01220.14 XP_011274680.1 - 3.4e-55 185.2 0.1 3.8e-55 185.0 0.0 1.0 1 0 0 1 1 1 1 Dehydroquinase class II GCR1_C PF12550.3 XP_011274682.1 - 1.9e-13 50.0 0.1 3.8e-13 49.0 0.1 1.5 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Hamartin PF04388.7 XP_011274682.1 - 0.01 14.5 14.9 0.013 14.1 10.3 1.1 1 0 0 1 1 1 0 Hamartin protein eIF3_subunit PF08597.5 XP_011274682.1 - 0.026 14.1 10.0 0.042 13.4 6.9 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Spore_coat_CotO PF14153.1 XP_011274682.1 - 0.046 13.1 14.2 0.076 12.4 9.8 1.4 1 0 0 1 1 1 0 Spore coat protein CotO RR_TM4-6 PF06459.7 XP_011274682.1 - 0.068 13.0 10.5 0.11 12.4 7.3 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Med15 PF09606.5 XP_011274682.1 - 0.15 10.2 56.4 0.19 9.8 39.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Dala_Dala_lig_N PF01820.16 XP_011274682.1 - 0.3 11.4 7.5 0.84 9.9 5.2 1.8 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus DUF3450 PF11932.3 XP_011274682.1 - 0.41 9.8 32.6 0.43 9.8 20.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) PAT1 PF09770.4 XP_011274682.1 - 2.9 6.0 48.2 3.9 5.5 33.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DHHW PF14286.1 XP_011274682.1 - 7.5 5.7 18.1 14 4.9 12.5 1.4 1 0 0 1 1 1 0 DHHW protein Macoilin PF09726.4 XP_011274682.1 - 9.6 4.3 23.7 14 3.8 16.4 1.3 1 0 0 1 1 1 0 Transmembrane protein Flavin_Reduct PF01613.13 XP_011274683.1 - 1e-18 67.6 0.0 1.6e-18 67.0 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain DUF447 PF04289.7 XP_011274683.1 - 0.068 12.7 0.0 0.092 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF447) SPAM PF02090.10 XP_011274683.1 - 0.15 12.0 0.2 0.22 11.4 0.2 1.2 1 0 0 1 1 1 0 Salmonella surface presentation of antigen gene type M protein CoA_trans PF01144.18 XP_011274684.1 - 1.7e-85 285.6 0.5 1e-55 188.2 0.0 2.0 2 0 0 2 2 2 2 Coenzyme A transferase Sad1_UNC PF07738.8 XP_011274684.1 - 0.13 12.0 0.5 3.8 7.3 0.2 2.5 2 1 0 2 2 2 0 Sad1 / UNC-like C-terminal GIY-YIG PF01541.19 XP_011274685.1 - 1.2e-09 38.4 0.0 3.8e-09 36.7 0.0 1.9 1 0 0 1 1 1 1 GIY-YIG catalytic domain T5orf172 PF10544.4 XP_011274685.1 - 0.1 13.0 0.0 0.31 11.4 0.0 1.9 1 1 0 1 1 1 0 T5orf172 domain DUF2256 PF10013.4 XP_011274685.1 - 0.12 12.1 1.1 15 5.3 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-HC5HC2H_2 PF13832.1 XP_011274685.1 - 0.12 12.3 1.7 0.18 11.8 0.6 1.7 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_2 PF13639.1 XP_011274685.1 - 0.14 12.0 6.2 0.43 10.4 4.3 1.9 1 1 0 1 1 1 0 Ring finger domain Vps39_2 PF10367.4 XP_011274685.1 - 0.38 10.9 2.6 15 5.8 0.1 2.5 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-rbx1 PF12678.2 XP_011274685.1 - 0.67 10.1 4.5 0.14 12.2 0.5 1.8 2 0 0 2 2 2 0 RING-H2 zinc finger zf-RING-like PF08746.6 XP_011274685.1 - 1.6 8.7 6.6 0.53 10.3 0.8 2.4 2 0 0 2 2 2 0 RING-like domain FANCL_C PF11793.3 XP_011274685.1 - 1.8 8.5 6.4 0.63 10.0 1.7 2.2 2 1 0 2 2 2 0 FANCL C-terminal domain DUF4182 PF13790.1 XP_011274685.1 - 7.2 6.4 8.0 1.1 9.1 2.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4182) Glyco_hydro_31 PF01055.21 XP_011274686.1 - 2e-144 481.7 1.3 2.6e-144 481.3 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 XP_011274686.1 - 1.5e-22 79.1 0.5 6.4e-22 77.1 0.0 2.3 2 0 0 2 2 2 1 Galactose mutarotase-like DUF1501 PF07394.7 XP_011274687.1 - 0.084 11.6 0.3 0.081 11.7 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) HGTP_anticodon2 PF12745.2 XP_011274687.1 - 5 6.1 12.1 6 5.9 8.4 1.0 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs CDC27 PF09507.5 XP_011274688.1 - 1.7e-31 109.9 45.8 2.1e-31 109.5 31.8 1.1 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 eIF3_N PF09440.5 XP_011274689.1 - 1.5e-32 112.5 3.0 1.5e-32 112.5 2.1 1.9 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 XP_011274689.1 - 4.3e-11 43.0 0.3 1.6e-10 41.1 0.2 2.1 1 0 0 1 1 1 1 PCI domain PCI_Csn8 PF10075.4 XP_011274689.1 - 0.0036 17.0 0.9 0.012 15.4 0.1 2.3 3 0 0 3 3 3 1 COP9 signalosome, subunit CSN8 Ribosomal_L17 PF01196.14 XP_011274690.1 - 2.5e-30 104.9 1.2 3.8e-30 104.3 0.5 1.6 2 0 0 2 2 2 1 Ribosomal protein L17 DUF2757 PF10955.3 XP_011274690.1 - 0.017 15.3 0.0 0.034 14.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2757) GatB_Yqey PF02637.13 XP_011274690.1 - 0.039 13.6 0.3 0.091 12.4 0.0 1.7 2 0 0 2 2 2 0 GatB domain DUF3216 PF11505.3 XP_011274691.1 - 0.07 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) H_PPase PF03030.11 XP_011274691.1 - 0.18 9.9 0.3 1.5 7.0 0.0 1.9 2 0 0 2 2 2 0 Inorganic H+ pyrophosphatase adh_short PF00106.20 XP_011274692.1 - 5.4e-23 81.7 0.0 6.6e-23 81.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 XP_011274692.1 - 4.2e-13 49.3 0.0 5.7e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 XP_011274692.1 - 8.2e-13 48.6 0.0 1.2e-12 48.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 XP_011274692.1 - 9.1e-07 29.0 0.0 4.5e-06 26.8 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 XP_011274692.1 - 2.1e-06 26.8 0.2 3e-06 26.3 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Methyltransf_25 PF13649.1 XP_011274692.1 - 1.3e-05 25.4 0.0 0.025 14.9 0.0 2.2 1 1 1 2 2 2 2 Methyltransferase domain Epimerase PF01370.16 XP_011274692.1 - 7.2e-05 22.3 0.0 9.3e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 XP_011274692.1 - 0.00062 19.8 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 XP_011274692.1 - 0.001 18.1 0.1 0.002 17.1 0.0 1.5 2 0 0 2 2 2 1 Saccharopine dehydrogenase NAD_binding_7 PF13241.1 XP_011274692.1 - 0.0033 17.6 0.1 0.0061 16.8 0.1 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Glyco_trans_4_2 PF13477.1 XP_011274692.1 - 0.0065 16.2 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like NAD_binding_2 PF03446.10 XP_011274692.1 - 0.014 15.2 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DHQS PF01959.11 XP_011274692.1 - 0.023 13.3 0.3 0.034 12.8 0.2 1.2 1 0 0 1 1 1 0 3-dehydroquinate synthase (EC 4.6.1.3) DUF262 PF03235.9 XP_011274692.1 - 0.029 14.3 0.2 0.052 13.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF262 3HCDH_N PF02737.13 XP_011274692.1 - 0.039 13.5 0.0 0.066 12.8 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 XP_011274692.1 - 0.055 13.8 0.2 0.12 12.8 0.0 1.7 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase Imm8 PF15560.1 XP_011274692.1 - 0.06 13.0 0.2 0.16 11.6 0.2 1.7 1 0 0 1 1 1 0 Immunity protein 8 UCH PF00443.24 XP_011274693.1 - 1.1e-43 149.2 6.0 1.1e-43 149.2 4.2 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 XP_011274693.1 - 1.3e-22 79.6 1.8 1.3e-22 79.6 1.2 2.1 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.26 XP_011274693.1 - 2.3e-17 62.2 0.0 1.1e-07 31.4 0.0 2.4 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.1 XP_011274693.1 - 2.9e-16 59.7 13.2 2.9e-16 59.7 9.1 2.8 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase IL31 PF15209.1 XP_011274694.1 - 0.017 14.7 0.1 0.031 13.8 0.1 1.4 1 0 0 1 1 1 0 Interleukin 31 Sld5 PF05916.6 XP_011274695.1 - 0.001 19.3 3.5 0.0021 18.3 2.0 1.8 1 1 0 1 1 1 1 GINS complex protein RFX_DNA_binding PF02257.10 XP_011274696.1 - 2.2e-34 117.4 0.2 5.7e-34 116.1 0.0 1.8 2 0 0 2 2 2 1 RFX DNA-binding domain Pox_D5 PF03288.11 XP_011274696.1 - 9.8e-06 25.7 0.0 6e-05 23.2 0.0 2.3 2 0 0 2 2 2 1 Poxvirus D5 protein-like GCIP PF13324.1 XP_011274697.1 - 6.1e-08 32.2 0.0 1e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting DUF2935 PF11155.3 XP_011274697.1 - 0.074 13.1 3.6 0.095 12.7 0.6 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) PMC2NT PF08066.7 XP_011274697.1 - 0.1 12.9 2.0 2.4 8.5 0.1 3.1 2 1 1 3 3 3 0 PMC2NT (NUC016) domain DUF16 PF01519.11 XP_011274697.1 - 0.76 10.0 4.0 0.68 10.1 0.3 2.6 3 0 0 3 3 3 0 Protein of unknown function DUF16 WH1 PF00568.18 XP_011274698.1 - 5.4e-32 109.8 0.0 1e-31 108.9 0.0 1.4 2 0 0 2 2 2 1 WH1 domain WH2 PF02205.15 XP_011274698.1 - 1e-05 24.9 1.5 1e-05 24.9 1.1 2.0 2 0 0 2 2 2 1 WH2 motif WD40 PF00400.27 XP_011274699.1 - 2.2e-44 147.7 20.2 3.5e-12 45.6 0.1 7.5 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 XP_011274699.1 - 6.1e-10 37.8 15.4 0.0072 14.5 0.1 5.0 3 2 2 5 5 5 5 Nucleoporin Nup120/160 DUF3312 PF11768.3 XP_011274699.1 - 1.8e-05 23.2 0.3 0.00015 20.1 0.0 2.1 1 1 1 3 3 3 1 Protein of unknown function (DUF3312) Nucleoporin_N PF08801.6 XP_011274699.1 - 2.8e-05 23.0 4.6 0.13 10.9 1.0 3.8 1 1 1 2 2 2 2 Nup133 N terminal like Hira PF07569.6 XP_011274699.1 - 0.00078 18.7 3.2 0.66 9.1 0.1 3.9 2 1 3 5 5 5 2 TUP1-like enhancer of split Hydrolase_like2 PF13246.1 XP_011274699.1 - 0.026 14.4 0.0 0.29 11.1 0.0 2.3 2 0 0 2 2 2 0 Putative hydrolase of sodium-potassium ATPase alpha subunit DUF1611 PF07755.6 XP_011274699.1 - 0.058 12.0 0.0 3.4 6.2 0.0 3.3 3 2 2 5 5 5 0 Protein of unknown function (DUF1611) SUKH_5 PF14567.1 XP_011274699.1 - 0.43 10.0 2.4 4.3 6.8 0.1 3.3 2 1 2 4 4 4 0 SMI1-KNR4 cell-wall DnaJ PF00226.26 XP_011274700.1 - 6e-25 86.7 1.5 9.3e-25 86.1 1.0 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 XP_011274700.1 - 6.9e-22 77.1 0.2 2e-17 62.8 0.0 2.7 2 1 0 2 2 2 2 DnaJ C terminal domain DKCLD PF08068.7 XP_011274701.1 - 5.2e-30 103.1 0.1 2.2e-29 101.1 0.0 2.1 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 XP_011274701.1 - 1.4e-22 80.4 0.0 1.1e-19 71.0 0.0 3.3 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 XP_011274701.1 - 1.4e-19 69.5 1.0 2.6e-19 68.7 0.7 1.4 1 0 0 1 1 1 1 PUA domain GAGA_bind PF06217.7 XP_011274701.1 - 0.15 12.0 10.5 0.21 11.5 7.3 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family FLO_LFY PF01698.11 XP_011274701.1 - 1.6 7.5 11.4 2 7.1 7.9 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein RNA_polI_A34 PF08208.6 XP_011274701.1 - 2.2 7.9 33.0 3.7 7.1 22.9 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 UEV PF05743.8 XP_011274702.1 - 2.1e-36 124.2 0.1 4.3e-36 123.2 0.0 1.5 1 0 0 1 1 1 1 UEV domain Atrophin-1 PF03154.10 XP_011274702.1 - 1.2 7.1 15.4 1.6 6.7 10.7 1.1 1 0 0 1 1 1 0 Atrophin-1 family UQ_con PF00179.21 XP_011274702.1 - 1.5 8.2 5.8 0.17 11.3 0.6 2.1 2 1 0 2 2 2 0 Ubiquitin-conjugating enzyme Zip PF02535.17 XP_011274704.1 - 2.4e-53 181.2 3.3 2.8e-53 181.0 2.3 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter YhfZ_C PF14503.1 XP_011274704.1 - 0.091 12.0 0.4 0.15 11.4 0.3 1.2 1 0 0 1 1 1 0 YhfZ C-terminal domain DUF869 PF05911.6 XP_011274706.1 - 0.0062 14.8 7.0 0.008 14.4 4.9 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) CAF-1_p150 PF11600.3 XP_011274706.1 - 0.34 10.2 10.2 0.57 9.5 7.1 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal HMG_box PF00505.14 XP_011274707.1 - 6.9e-11 42.2 2.9 6.9e-11 42.2 2.0 2.1 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 XP_011274707.1 - 1.8e-06 28.2 1.9 6.2e-06 26.4 1.3 2.0 1 0 0 1 1 1 1 HMG-box domain FimP PF09766.4 XP_011274707.1 - 0.002 17.2 3.8 0.002 17.2 2.7 2.3 2 1 0 2 2 2 1 Fms-interacting protein MRP-S28 PF10213.4 XP_011274708.1 - 4.2e-37 127.0 2.0 8.9e-37 125.9 1.4 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein F-box PF00646.28 XP_011274709.1 - 0.0046 16.5 0.2 0.013 15.1 0.2 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 XP_011274709.1 - 0.02 14.6 0.5 0.04 13.6 0.4 1.5 1 0 0 1 1 1 0 F-box-like Ada3 PF10198.4 XP_011274710.1 - 8.5e-42 142.0 6.8 8.5e-42 142.0 4.7 2.4 3 1 0 3 3 3 1 Histone acetyltransferases subunit 3 Peptidase_M16 PF00675.15 XP_011274711.1 - 2.1e-51 173.5 0.0 5.5e-51 172.2 0.0 1.7 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 XP_011274711.1 - 3.1e-41 141.0 0.0 1e-38 132.8 0.0 2.3 2 0 0 2 2 2 2 Peptidase M16 inactive domain PCI PF01399.22 XP_011274712.1 - 1.9e-05 24.8 3.2 1.9e-05 24.8 2.2 2.6 3 0 0 3 3 3 1 PCI domain TPR_7 PF13176.1 XP_011274712.1 - 0.028 14.1 0.4 2.2 8.2 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 XP_011274712.1 - 0.25 10.9 2.4 9.1 6.0 0.7 3.3 2 1 0 2 2 2 0 TPR repeat Pex14_N PF04695.8 XP_011274713.1 - 4.3 7.3 10.3 33 4.5 5.7 2.4 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region AA_permease PF00324.16 XP_011274714.1 - 9.8e-99 330.8 41.7 1.3e-98 330.4 28.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 XP_011274714.1 - 1.4e-18 66.6 43.6 2.3e-18 65.9 30.2 1.3 1 1 0 1 1 1 1 Amino acid permease DUF1772 PF08592.6 XP_011274714.1 - 0.033 13.9 0.5 0.033 13.9 0.4 3.8 3 2 0 3 3 3 0 Domain of unknown function (DUF1772) Mannosyl_trans3 PF11051.3 XP_011274715.1 - 2.4e-58 197.6 1.2 4.2e-58 196.8 0.8 1.4 1 0 0 1 1 1 1 Mannosyltransferase putative Mannosyl_trans3 PF11051.3 XP_011274716.1 - 3.4e-59 200.4 0.1 5.5e-59 199.7 0.1 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative Serglycin PF04360.7 XP_011274716.1 - 0.073 12.7 0.3 0.18 11.5 0.2 1.6 1 0 0 1 1 1 0 Serglycin PH PF00169.24 XP_011274717.1 - 4.3e-06 26.8 0.6 8.4e-05 22.7 0.0 2.5 2 0 0 2 2 2 1 PH domain PH_9 PF15410.1 XP_011274717.1 - 0.022 14.8 0.2 0.11 12.6 0.0 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain Lipoprotein_19 PF13617.1 XP_011274717.1 - 0.53 9.9 1.5 1.2 8.8 1.1 1.5 1 0 0 1 1 1 0 YnbE-like lipoprotein Oxysterol_BP PF01237.13 XP_011274718.1 - 3.1e-125 417.3 0.0 5e-125 416.6 0.0 1.3 1 0 0 1 1 1 1 Oxysterol-binding protein Ank_5 PF13857.1 XP_011274718.1 - 3.2e-13 49.4 0.0 3.3e-07 30.3 0.2 3.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 XP_011274718.1 - 4.2e-13 49.4 0.5 1.1e-06 28.8 0.3 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 XP_011274718.1 - 3.3e-12 46.5 0.1 1.9e-06 28.1 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 XP_011274718.1 - 7.4e-10 38.1 0.0 0.0024 17.6 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat PH_8 PF15409.1 XP_011274718.1 - 8.3e-08 32.1 2.6 2.1e-07 30.9 0.3 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain Ank_3 PF13606.1 XP_011274718.1 - 1.1e-07 31.3 0.0 0.011 15.9 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat PH PF00169.24 XP_011274718.1 - 1.9e-07 31.2 0.5 5e-07 29.8 0.4 1.8 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 XP_011274718.1 - 1.2e-05 25.5 5.0 1.4e-05 25.3 1.5 2.7 2 1 0 2 2 2 1 Pleckstrin homology domain Pkinase PF00069.20 XP_011274719.1 - 2.7e-77 259.4 0.0 5.7e-77 258.3 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011274719.1 - 2.1e-38 131.9 0.0 4.1e-38 130.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 XP_011274719.1 - 1.3e-27 95.6 1.8 5.9e-15 55.1 0.1 3.8 4 0 0 4 4 4 2 FHA domain Kinase-like PF14531.1 XP_011274719.1 - 3.6e-08 32.7 0.0 1e-07 31.2 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 XP_011274719.1 - 2.8e-06 27.2 0.0 0.024 14.3 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 XP_011274719.1 - 8.9e-06 24.9 0.0 2.6e-05 23.3 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 XP_011274719.1 - 0.00099 18.5 0.1 0.0053 16.1 0.0 2.1 2 0 0 2 2 2 1 RIO1 family DIOX_N PF14226.1 XP_011274720.1 - 5.6e-27 94.5 0.5 2.3e-26 92.6 0.0 2.2 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 XP_011274720.1 - 1.7e-13 50.6 0.0 3.2e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF4201 PF13870.1 XP_011274720.1 - 0.26 10.6 3.7 1.9 7.9 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4201) R3H PF01424.17 XP_011274722.1 - 0.00069 19.2 0.1 12 5.6 0.0 3.5 3 0 0 3 3 3 3 R3H domain WD40 PF00400.27 XP_011274723.1 - 3.8e-10 39.2 4.6 0.00032 20.4 0.4 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat Abhydrolase_9 PF10081.4 XP_011274723.1 - 0.048 12.3 0.0 0.08 11.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta-hydrolase family ABC2_membrane PF01061.19 XP_011274724.1 - 7.5e-17 61.1 16.9 7.5e-17 61.1 11.7 2.0 2 0 0 2 2 2 1 ABC-2 type transporter PDR_CDR PF06422.7 XP_011274724.1 - 0.0053 16.3 0.4 0.0053 16.3 0.3 2.2 2 0 0 2 2 2 1 CDR ABC transporter DUF3507 PF12015.3 XP_011274725.1 - 9.4e-51 171.9 0.9 9.4e-51 171.9 0.6 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF3507) DUF2036 PF09724.4 XP_011274726.1 - 7.8e-66 222.4 3.1 1.6e-65 221.4 2.2 1.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) YcgR_2 PF12945.2 XP_011274726.1 - 0.04 13.7 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 Flagellar protein YcgR Mito_carr PF00153.22 XP_011274727.1 - 1.3e-54 181.8 6.7 5.2e-20 70.9 0.2 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein YtxH PF12732.2 XP_011274727.1 - 0.12 12.7 0.4 2.1 8.7 0.1 2.4 2 0 0 2 2 2 0 YtxH-like protein Aminotran_5 PF00266.14 XP_011274728.1 - 1.7e-99 333.0 0.0 2.1e-99 332.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 XP_011274728.1 - 1.8e-09 37.2 0.0 2.2e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 XP_011274728.1 - 4.7e-08 32.4 0.0 2.5e-07 30.0 0.0 1.9 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.14 XP_011274728.1 - 0.0015 17.0 0.0 0.0024 16.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain B12-binding PF02310.14 XP_011274728.1 - 0.04 13.7 0.0 0.73 9.7 0.0 2.4 2 0 0 2 2 2 0 B12 binding domain EF-hand_6 PF13405.1 XP_011274728.1 - 0.12 12.3 0.0 0.52 10.3 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain Iso_dh PF00180.15 XP_011274729.1 - 1.6e-130 435.0 0.0 1.9e-130 434.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Ribosomal_L30 PF00327.15 XP_011274730.1 - 2.5e-16 59.0 1.1 5.6e-16 57.8 0.4 2.0 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e DNA_pol_viral_C PF00336.13 XP_011274730.1 - 0.011 14.9 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) C-terminal domain Methyltransf_25 PF13649.1 XP_011274732.1 - 0.0014 18.9 0.1 0.003 17.8 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 XP_011274732.1 - 0.0096 15.2 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_23 PF13489.1 XP_011274732.1 - 0.0096 15.6 0.0 0.015 15.0 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 XP_011274732.1 - 0.066 13.7 0.0 0.11 13.0 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain RRM_1 PF00076.17 XP_011274734.1 - 2.1e-23 81.7 0.5 4e-14 51.9 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 XP_011274734.1 - 2.8e-17 62.4 0.1 2.7e-08 33.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 XP_011274734.1 - 1.2e-07 31.4 0.1 0.017 14.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Syndecan PF01034.15 XP_011274735.1 - 0.031 13.9 0.0 0.067 12.8 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain DUF912 PF06024.7 XP_011274735.1 - 0.55 10.3 0.0 0.55 10.3 0.0 4.8 5 3 1 6 6 6 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Ribosomal_L22 PF00237.14 XP_011274736.1 - 6.2e-16 58.2 0.2 2.2e-15 56.4 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e SPC12 PF06645.8 XP_011274737.1 - 0.038 13.7 1.6 0.038 13.7 1.1 1.6 1 1 0 1 1 1 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Glucos_trans_II PF14264.1 XP_011274739.1 - 0.0066 15.4 0.2 0.0073 15.3 0.1 1.1 1 0 0 1 1 1 1 Glucosyl transferase GtrII FlaG PF03646.10 XP_011274739.1 - 0.038 14.1 0.2 0.059 13.5 0.1 1.3 1 0 0 1 1 1 0 FlaG protein FGGY_N PF00370.16 XP_011274739.1 - 0.073 12.3 0.1 0.097 11.9 0.1 1.1 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain TFIIA_gamma_C PF02751.9 XP_011274739.1 - 0.099 12.4 0.2 0.54 10.1 0.2 2.0 2 0 0 2 2 2 0 Transcription initiation factor IIA, gamma subunit PC_rep PF01851.17 XP_011274741.1 - 4e-45 149.5 17.9 1.4e-06 28.1 0.2 9.7 9 0 0 9 9 9 7 Proteasome/cyclosome repeat HEAT_2 PF13646.1 XP_011274741.1 - 4.6e-17 62.0 0.7 5.8e-13 48.9 0.0 4.2 3 1 2 5 5 5 2 HEAT repeats HEAT_EZ PF13513.1 XP_011274741.1 - 1.7e-08 34.7 0.0 0.037 14.5 0.0 4.4 3 1 1 4 4 4 3 HEAT-like repeat HEAT PF02985.17 XP_011274741.1 - 3.6e-07 29.6 0.7 1.4 9.1 0.0 5.2 5 0 0 5 5 5 2 HEAT repeat Arm PF00514.18 XP_011274741.1 - 0.0086 15.8 0.2 0.15 11.9 0.0 3.3 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Telomere_reg-2 PF10193.4 XP_011274741.1 - 0.41 10.9 0.0 0.41 10.9 0.0 3.6 4 1 0 4 4 4 0 Telomere length regulation protein Vfa1 PF08432.5 XP_011274741.1 - 0.43 10.5 20.6 1 9.3 14.3 1.6 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RP-C_C PF11800.3 XP_011274741.1 - 7.2 6.2 8.3 17 5.0 5.7 1.6 1 0 0 1 1 1 0 Replication protein C C-terminal region 2-Hacid_dh_C PF02826.14 XP_011274743.1 - 1e-51 174.6 0.0 1.7e-51 173.8 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 XP_011274743.1 - 8.8e-35 119.0 0.1 1.1e-34 118.7 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 XP_011274743.1 - 0.00017 21.4 0.2 0.0004 20.2 0.1 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 XP_011274743.1 - 0.00049 19.9 0.1 0.00096 19.0 0.0 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Acetyltransf_1 PF00583.19 XP_011274743.1 - 0.013 15.5 0.0 0.075 13.0 0.0 2.3 1 1 1 2 2 2 0 Acetyltransferase (GNAT) family ACT PF01842.20 XP_011274743.1 - 0.023 14.1 0.0 0.061 12.8 0.0 1.7 1 0 0 1 1 1 0 ACT domain IlvN PF07991.7 XP_011274743.1 - 0.029 13.7 0.0 0.068 12.5 0.0 1.6 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain XdhC_C PF13478.1 XP_011274743.1 - 0.063 13.5 0.0 0.17 12.2 0.0 1.8 1 0 0 1 1 1 0 XdhC Rossmann domain Sugar_tr PF00083.19 XP_011274744.1 - 1.7e-46 158.7 23.6 2.4e-46 158.2 16.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 XP_011274744.1 - 3.3e-34 118.1 32.1 5.1e-34 117.5 22.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily ATG22 PF11700.3 XP_011274744.1 - 0.00031 19.3 4.4 0.00031 19.3 3.1 2.2 2 0 0 2 2 2 2 Vacuole effluxer Atg22 like Sugar_tr PF00083.19 XP_011274745.1 - 3.3e-47 161.0 24.9 4e-47 160.8 17.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 XP_011274745.1 - 9.6e-40 136.3 29.0 1.4e-39 135.8 20.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily ATG22 PF11700.3 XP_011274745.1 - 1e-05 24.2 28.2 0.00015 20.3 9.4 2.1 1 1 1 2 2 2 2 Vacuole effluxer Atg22 like MFS_1_like PF12832.2 XP_011274745.1 - 0.0023 17.6 1.2 0.0099 15.6 0.0 2.7 3 0 0 3 3 3 1 MFS_1 like family Pex24p PF06398.6 XP_011274745.1 - 0.057 12.2 2.0 0.095 11.4 1.4 1.3 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Sugar_tr PF00083.19 XP_011274746.1 - 4.4e-44 150.7 25.0 5.7e-44 150.4 17.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 XP_011274746.1 - 1.7e-34 119.1 33.0 2.9e-34 118.3 22.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily ATG22 PF11700.3 XP_011274746.1 - 1.5e-05 23.7 5.0 1.5e-05 23.7 3.5 2.3 2 0 0 2 2 2 1 Vacuole effluxer Atg22 like MMR_HSR1_C PF08438.5 XP_011274747.1 - 3.2e-31 107.7 0.1 6e-31 106.9 0.1 1.5 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 XP_011274747.1 - 7.4e-14 51.7 0.0 2e-13 50.3 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 XP_011274747.1 - 0.022 14.2 0.9 1.5 8.2 0.0 2.8 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 XP_011274747.1 - 0.031 13.5 0.3 0.51 9.6 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_18 PF13238.1 XP_011274747.1 - 0.42 10.9 1.8 12 6.1 0.2 2.7 2 1 0 2 2 2 0 AAA domain ADH_N PF08240.7 XP_011274749.1 - 5.8e-31 106.4 0.8 5.8e-31 106.4 0.6 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 XP_011274749.1 - 6.8e-24 83.8 0.2 1.1e-23 83.1 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 XP_011274749.1 - 2.7e-05 25.0 0.1 4.9e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 XP_011274749.1 - 0.016 14.3 0.3 0.028 13.5 0.2 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DapB_N PF01113.15 XP_011274749.1 - 0.066 13.1 1.0 0.45 10.4 0.6 2.1 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus ACP_syn_III_C PF08541.5 XP_011274749.1 - 0.12 12.4 0.2 0.27 11.2 0.2 1.6 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal SKG6 PF08693.5 XP_011274750.1 - 2.2e-07 30.0 0.0 6.6e-07 28.5 0.0 1.9 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM213 PF15192.1 XP_011274750.1 - 0.0087 16.0 1.3 0.022 14.7 0.9 1.6 1 0 0 1 1 1 1 TMEM213 family Ribosomal_S4 PF00163.14 XP_011274751.1 - 5.1e-24 84.4 1.2 7.2e-24 83.9 0.8 1.2 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 XP_011274751.1 - 2.7e-11 42.6 0.0 1.9e-10 40.0 0.0 2.1 2 0 0 2 2 2 1 S4 domain Rsm1 PF08600.5 XP_011274751.1 - 0.064 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Rsm1-like Ribosomal_L6 PF00347.18 XP_011274752.1 - 1.5e-27 95.8 1.1 3.1e-13 50.0 0.0 2.9 2 1 1 3 3 3 2 Ribosomal protein L6 Ribosomal_L3 PF00297.17 XP_011274753.1 - 4.6e-46 157.3 1.5 4.5e-45 154.1 1.1 2.0 1 1 0 1 1 1 1 Ribosomal protein L3 RE_XcyI PF09571.5 XP_011274753.1 - 0.033 13.0 0.1 0.047 12.5 0.1 1.2 1 0 0 1 1 1 0 XcyI restriction endonuclease CRM1_C PF08767.6 XP_011274754.1 - 7.8e-125 416.0 1.6 7.8e-125 416.0 1.1 3.1 3 0 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.7 XP_011274754.1 - 4.3e-38 130.5 9.6 6.4e-38 129.9 2.0 4.0 4 0 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.14 XP_011274754.1 - 6.1e-15 54.9 0.4 3.5e-14 52.4 0.3 2.5 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF496 PF04363.7 XP_011274755.1 - 4.5 7.1 8.8 16 5.4 4.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF496) Ank_2 PF12796.2 XP_011274756.1 - 1.9e-44 149.8 7.6 2.9e-14 53.1 0.0 4.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 XP_011274756.1 - 1.4e-28 97.2 5.1 6.1e-05 22.6 0.0 6.9 7 0 0 7 7 7 6 Ankyrin repeat SPX PF03105.14 XP_011274756.1 - 1.2e-26 94.1 18.9 9.5e-13 48.5 7.2 3.2 1 1 1 2 2 2 2 SPX domain Ank_3 PF13606.1 XP_011274756.1 - 3.3e-23 79.4 2.4 0.0016 18.4 0.0 7.1 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.1 XP_011274756.1 - 9.3e-23 80.1 0.6 3.2e-05 24.3 0.0 5.1 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 XP_011274756.1 - 1.1e-22 79.4 1.4 2.4e-05 24.4 0.0 5.9 1 1 5 6 6 6 6 Ankyrin repeats (many copies) GDPD PF03009.12 XP_011274756.1 - 1.2e-11 44.5 0.0 3e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family BING4CT PF08149.6 XP_011274757.1 - 1.9e-37 126.5 1.3 1.4e-34 117.4 0.0 4.1 5 0 0 5 5 5 1 BING4CT (NUC141) domain WD40 PF00400.27 XP_011274757.1 - 6.4e-10 38.5 0.0 5e-06 26.2 0.0 4.5 5 0 0 5 5 5 2 WD domain, G-beta repeat Ribosomal_L21p PF00829.16 XP_011274758.1 - 0.1 12.7 0.1 0.19 11.8 0.1 1.4 1 0 0 1 1 1 0 Ribosomal prokaryotic L21 protein IF4E PF01652.13 XP_011274759.1 - 0.00011 21.8 0.0 0.00015 21.3 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Rota_NS6 PF04866.7 XP_011274760.1 - 0.025 14.5 0.4 0.087 12.8 0.3 1.9 1 0 0 1 1 1 0 Rotavirus non-structural protein 6 LRR_8 PF13855.1 XP_011274760.1 - 0.14 11.9 9.4 2.3 8.0 0.1 4.0 4 0 0 4 4 4 0 Leucine rich repeat zf-RING_2 PF13639.1 XP_011274761.1 - 2.2e-09 36.9 4.1 4.8e-09 35.8 2.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 XP_011274761.1 - 4.8e-07 29.7 0.5 4.8e-07 29.7 0.3 2.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 XP_011274761.1 - 1.6e-06 28.0 0.5 3.8e-06 26.9 0.4 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 XP_011274761.1 - 6.5e-06 25.7 1.7 6.5e-06 25.7 1.2 2.0 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 XP_011274761.1 - 7.5e-06 25.5 1.4 1.7e-05 24.4 0.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 XP_011274761.1 - 2.9e-05 23.6 0.4 9.5e-05 21.9 0.3 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 XP_011274761.1 - 0.012 15.5 0.9 0.033 14.1 0.6 1.8 1 0 0 1 1 1 0 FANCL C-terminal domain zf-Apc11 PF12861.2 XP_011274761.1 - 0.15 11.9 2.8 0.37 10.6 2.0 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 XP_011274761.1 - 0.27 10.7 1.9 0.66 9.5 1.3 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 XP_011274761.1 - 0.3 10.8 2.5 0.39 10.4 0.6 2.1 1 1 0 1 1 1 0 RING-type zinc-finger DHO_dh PF01180.16 XP_011274762.1 - 4.3e-93 311.4 0.1 5.1e-93 311.2 0.1 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase DUF615 PF04751.9 XP_011274762.1 - 0.014 14.9 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF615) Aldo_ket_red PF00248.16 XP_011274763.1 - 4.1e-45 153.8 0.1 5.4e-45 153.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family GET2 PF08690.5 XP_011274764.1 - 2.5e-31 109.0 16.7 5.9e-31 107.8 11.6 1.5 1 1 0 1 1 1 1 GET complex subunit GET2 Pro-MCH PF05824.7 XP_011274764.1 - 0.1 12.1 0.0 0.25 10.8 0.0 1.6 1 0 0 1 1 1 0 Pro-melanin-concentrating hormone (Pro-MCH) FliE PF02049.13 XP_011274764.1 - 1 9.3 7.4 0.088 12.8 0.5 2.4 3 0 0 3 3 3 0 Flagellar hook-basal body complex protein FliE zf-CHCC PF10276.4 XP_011274765.1 - 2.3e-13 49.7 0.3 3.3e-13 49.2 0.2 1.3 1 0 0 1 1 1 1 Zinc-finger domain Metaviral_G PF09595.5 XP_011274765.1 - 0.019 14.5 1.4 0.025 14.2 1.0 1.1 1 0 0 1 1 1 0 Metaviral_G glycoprotein CTNNB1_binding PF08347.6 XP_011274765.1 - 0.067 13.4 0.1 0.081 13.1 0.0 1.1 1 0 0 1 1 1 0 N-terminal CTNNB1 binding Staphylokinase PF02821.11 XP_011274766.1 - 0.023 14.4 0.4 0.029 14.1 0.3 1.1 1 0 0 1 1 1 0 Staphylokinase/Streptokinase family DUF3237 PF11578.3 XP_011274767.1 - 1.3e-11 43.9 0.0 1.5e-11 43.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) DUF3237 PF11578.3 XP_011274768.1 - 1e-09 37.8 0.0 1.1e-09 37.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) DUF2713 PF10897.3 XP_011274768.1 - 0.0034 16.6 0.1 0.0043 16.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2713) DUF3237 PF11578.3 XP_011274769.1 - 1e-11 44.3 0.0 1.1e-11 44.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) DUF1824 PF08854.5 XP_011274769.1 - 0.087 12.4 0.0 11 5.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1824) Coatomer_E PF04733.9 XP_011274770.1 - 7.3e-40 136.9 8.8 8.3e-40 136.7 6.1 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.1 XP_011274770.1 - 4.4e-05 23.7 3.8 0.00015 22.0 0.3 3.3 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 XP_011274770.1 - 0.024 14.4 0.8 5.2 7.1 0.1 3.7 4 1 0 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 XP_011274770.1 - 0.032 14.3 4.4 1.4 9.1 0.1 3.2 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 XP_011274770.1 - 0.036 13.7 1.3 2 8.1 0.3 3.1 2 1 1 3 3 3 0 TPR repeat Hydrolase PF00702.21 XP_011274770.1 - 0.04 14.3 0.0 0.07 13.5 0.0 1.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase TPR_14 PF13428.1 XP_011274770.1 - 0.065 13.9 0.5 2.4 9.0 0.1 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_21 PF09976.4 XP_011274770.1 - 0.1 12.5 0.4 10 6.0 0.1 2.7 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 XP_011274770.1 - 0.12 12.3 3.7 5.2 7.0 0.1 4.1 2 2 1 4 4 4 0 Tetratricopeptide repeat DUF1689 PF07954.6 XP_011274771.1 - 1.5e-31 109.3 0.1 2.3e-31 108.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1689) tRNA-synt_2b PF00587.20 XP_011274772.1 - 6e-47 159.4 0.8 1.3e-46 158.3 0.6 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 XP_011274772.1 - 1.5e-19 69.7 1.8 3.7e-19 68.4 1.2 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.9 XP_011274772.1 - 5.9e-13 48.4 0.0 1.3e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.16 XP_011274772.1 - 3e-12 46.1 0.0 1.3e-10 40.9 0.0 2.7 3 0 0 3 3 3 1 TGS domain zf-CCHC PF00098.18 XP_011274773.1 - 3.8e-12 45.5 27.6 0.00011 21.9 1.4 4.7 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_3 PF13917.1 XP_011274773.1 - 0.00075 19.1 29.1 0.024 14.3 2.9 4.5 3 1 1 4 4 4 3 Zinc knuckle zf-CCHC_2 PF13696.1 XP_011274773.1 - 0.041 13.3 0.3 0.041 13.3 0.2 4.0 3 1 1 4 4 4 0 Zinc knuckle OrfB_Zn_ribbon PF07282.6 XP_011274773.1 - 1.7 8.3 27.1 0.41 10.3 6.6 2.8 2 1 1 3 3 3 0 Putative transposase DNA-binding domain Gmx_para_CXXCG PF09535.5 XP_011274773.1 - 4 6.3 6.9 5.6 5.8 2.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (Gmx_para_CXXCG) FAD-oxidase_C PF02913.14 XP_011274774.1 - 2.7e-43 148.0 0.0 4.3e-43 147.4 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 XP_011274774.1 - 1.2e-35 122.0 0.4 2.5e-35 120.9 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain UPF0029 PF01205.14 XP_011274775.1 - 3.1e-32 110.5 0.1 4e-32 110.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 DNA_gyraseA_C PF03989.8 XP_011274775.1 - 0.076 12.3 0.2 0.17 11.1 0.1 1.6 1 1 0 1 1 1 0 DNA gyrase C-terminal domain, beta-propeller BBS2_Mid PF14783.1 XP_011274776.1 - 0.021 14.5 0.1 1.6 8.5 0.0 3.0 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region CBM_20 PF00686.14 XP_011274776.1 - 0.09 12.3 0.1 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 Starch binding domain Pmp3 PF01679.12 XP_011274777.1 - 3.7e-18 64.9 8.2 4.7e-18 64.6 5.7 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Pmp3 PF01679.12 XP_011274778.1 - 1.6e-12 46.9 3.7 1.9e-12 46.6 2.6 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator CD47 PF04549.9 XP_011274778.1 - 0.075 13.0 0.1 0.092 12.7 0.1 1.1 1 0 0 1 1 1 0 CD47 transmembrane region DUF2953 PF11167.3 XP_011274778.1 - 0.33 10.8 1.5 0.54 10.2 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2953) Arrestin_C PF02752.17 XP_011274779.1 - 4.4e-21 75.4 0.0 4.4e-21 75.4 0.0 3.8 3 2 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 XP_011274779.1 - 0.0006 19.6 1.3 0.011 15.5 0.1 3.2 4 0 0 4 4 4 1 Arrestin (or S-antigen), N-terminal domain Pkinase PF00069.20 XP_011274780.1 - 2.3e-06 26.9 0.0 4e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Adaptin_N PF01602.15 XP_011274781.1 - 2.4e-106 356.1 23.5 2.8e-106 355.9 16.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 XP_011274781.1 - 3.2e-17 62.8 2.1 9.3e-17 61.3 1.4 1.8 1 0 0 1 1 1 1 Adaptin C-terminal domain TB2_DP1_HVA22 PF03134.14 XP_011274782.1 - 1.2e-31 108.3 3.7 1.5e-31 107.9 2.5 1.1 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Antimicrobial17 PF08129.6 XP_011274782.1 - 0.22 11.3 1.0 0.89 9.3 0.0 2.5 3 0 0 3 3 3 0 Alpha/beta enterocin family MFS_1 PF07690.11 XP_011274783.1 - 4.1e-43 147.4 33.5 1.3e-42 145.7 18.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 XP_011274783.1 - 1.1e-12 47.3 23.7 2.1e-12 46.3 16.4 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 XP_011274783.1 - 3.8e-06 25.3 3.6 3.8e-06 25.3 2.5 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) ICL PF00463.16 XP_011274784.1 - 1.9e-190 633.5 0.5 2.2e-190 633.3 0.3 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 XP_011274784.1 - 2.8e-10 39.8 0.0 4.9e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Arg_repressor_C PF02863.13 XP_011274784.1 - 0.036 13.5 0.0 0.078 12.4 0.0 1.6 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain Cu-oxidase_3 PF07732.10 XP_011274785.1 - 2.3e-45 153.1 6.2 8e-41 138.4 0.0 4.0 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 XP_011274785.1 - 1.1e-40 138.3 16.7 8.6e-39 132.1 1.5 4.3 4 1 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.17 XP_011274785.1 - 2.4e-27 95.7 1.0 2.4e-27 95.7 0.7 3.3 3 1 0 3 3 3 1 Multicopper oxidase DUF4064 PF13273.1 XP_011274785.1 - 0.0069 16.4 1.1 0.02 14.9 0.7 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) ABC2_membrane_3 PF12698.2 XP_011274785.1 - 0.012 14.6 0.2 0.019 14.0 0.1 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein SH3_2 PF07653.12 XP_011274785.1 - 0.015 14.8 0.1 5.4 6.5 0.0 2.5 2 0 0 2 2 2 0 Variant SH3 domain DUF2258 PF10015.4 XP_011274785.1 - 0.099 12.4 0.0 5.4 6.8 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2258) DUF605 PF04652.11 XP_011274786.1 - 1.4e-61 208.9 23.0 3.1e-61 207.8 15.9 1.5 1 1 0 1 1 1 1 Vta1 like LPP20 PF02169.11 XP_011274788.1 - 0.22 11.6 9.2 0.29 11.2 6.4 1.1 1 0 0 1 1 1 0 LPP20 lipoprotein Chlam_vir PF05475.6 XP_011274788.1 - 0.35 9.9 4.8 0.39 9.7 3.4 1.0 1 0 0 1 1 1 0 Chlamydia virulence protein PGP3-D Mucin PF01456.12 XP_011274788.1 - 1.9 8.2 17.3 2.2 8.0 12.0 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein Casein_kappa PF00997.13 XP_011274788.1 - 3.2 7.4 12.7 4.1 7.1 8.7 1.3 1 1 0 1 1 1 0 Kappa casein DUF2807 PF10988.3 XP_011274791.1 - 0.1 12.1 1.0 0.33 10.4 0.5 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2807) ADH_zinc_N PF00107.21 XP_011274792.1 - 2.4e-12 46.4 0.0 4.6e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 XP_011274792.1 - 2.3e-05 24.0 0.1 4.9e-05 23.0 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DUF1593 PF07632.6 XP_011274793.1 - 3.9e-90 301.6 0.6 5e-90 301.3 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) DUF1593 PF07632.6 XP_011274794.1 - 4.8e-88 294.8 0.1 6.3e-88 294.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) ADH_zinc_N PF00107.21 XP_011274795.1 - 2.5e-11 43.2 0.0 8.4e-11 41.5 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 XP_011274795.1 - 2.4e-06 27.2 0.0 4.7e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain 4HBT_2 PF13279.1 XP_011274796.1 - 1.1e-11 45.1 0.0 1.5e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF1823 PF08853.6 XP_011274796.1 - 0.084 12.6 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1823) RLL PF10036.4 XP_011274797.1 - 0.028 13.8 0.2 0.054 12.9 0.1 1.4 1 1 0 1 1 1 0 Putative carnitine deficiency-associated protein 4HBT_2 PF13279.1 XP_011274799.1 - 1.1e-09 38.7 0.0 1.6e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily FA_desaturase PF00487.19 XP_011274800.1 - 2.7e-28 99.1 14.2 5e-28 98.2 9.8 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 XP_011274800.1 - 3.6e-05 23.7 0.0 7.1e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) TMEM213 PF15192.1 XP_011274800.1 - 0.4 10.7 1.9 0.43 10.6 0.3 1.8 2 0 0 2 2 2 0 TMEM213 family DUF1201 PF06716.6 XP_011274801.1 - 0.49 10.2 10.9 0.038 13.7 1.6 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1201) DUF912 PF06024.7 XP_011274802.1 - 0.016 15.2 0.7 0.31 11.1 0.0 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Mito_carr PF00153.22 XP_011274803.1 - 2.2e-28 97.8 3.9 1.1e-12 47.4 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Mac-1 PF09028.5 XP_011274803.1 - 0.047 12.4 0.1 0.073 11.8 0.1 1.2 1 0 0 1 1 1 0 Mac 1 TPT PF03151.11 XP_011274804.1 - 5.3e-32 110.5 5.7 5.3e-32 110.5 3.9 2.5 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 XP_011274804.1 - 1.4e-07 31.6 27.3 1.4e-05 25.1 4.6 3.6 3 1 0 3 3 3 2 EamA-like transporter family UAA PF08449.6 XP_011274804.1 - 6.3e-05 22.0 20.4 0.00017 20.6 14.2 1.7 1 1 0 1 1 1 1 UAA transporter family SART-1 PF03343.8 XP_011274805.1 - 5.7e-104 348.6 107.3 1.2e-94 317.9 70.4 2.1 1 1 1 2 2 2 2 SART-1 family Nop PF01798.13 XP_011274806.1 - 3.6e-59 198.3 1.5 8.9e-59 197.0 1.0 1.7 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 XP_011274806.1 - 3.6e-26 90.7 0.0 8.2e-26 89.5 0.0 1.6 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 XP_011274806.1 - 3.1e-18 65.6 2.4 3.1e-18 65.6 1.6 2.9 2 1 1 3 3 3 1 NOP5NT (NUC127) domain GAGA_bind PF06217.7 XP_011274806.1 - 2.2 8.1 18.5 4.7 7.0 12.8 1.6 1 0 0 1 1 1 0 GAGA binding protein-like family CTP_transf_1 PF01148.15 XP_011274807.1 - 3.6e-20 72.7 12.7 2.3e-19 70.0 8.3 1.9 1 1 0 1 1 1 1 Cytidylyltransferase family Herpes_capsid PF06112.6 XP_011274807.1 - 0.18 11.8 0.2 10 6.1 0.0 2.2 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein Ribosomal_L18ae PF01775.12 XP_011274808.1 - 2.8e-56 188.7 0.4 3.8e-56 188.3 0.3 1.2 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain Glyco_transf_15 PF01793.11 XP_011274811.1 - 1.4e-127 425.2 22.9 2e-127 424.7 15.9 1.2 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Maelstrom PF13017.1 XP_011274812.1 - 0.28 10.6 3.3 0.82 9.1 0.2 2.4 2 0 0 2 2 2 0 piRNA pathway germ-plasm component Cation_efflux PF01545.16 XP_011274813.1 - 1.7e-80 270.1 5.9 2.2e-80 269.7 4.1 1.1 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.17 XP_011274813.1 - 8.6e-07 28.2 1.8 1.3e-06 27.6 1.2 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter MFS_1 PF07690.11 XP_011274814.1 - 5e-26 91.2 31.4 5e-26 91.2 21.8 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1228 PF06779.9 XP_011274814.1 - 0.022 14.7 0.2 0.022 14.7 0.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1228) MFS_1 PF07690.11 XP_011274815.1 - 7.3e-22 77.5 27.7 7.3e-22 77.5 19.2 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily YdfZ PF14001.1 XP_011274816.1 - 0.026 14.8 0.1 0.038 14.2 0.1 1.3 1 0 0 1 1 1 0 YdfZ protein DUF2874 PF11396.3 XP_011274817.1 - 0.92 9.5 4.3 0.65 10.0 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2874) SKN1 PF03935.10 XP_011274820.1 - 5.6e-244 809.8 5.5 6.8e-244 809.6 3.8 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) SUN PF03856.8 XP_011274821.1 - 3.8e-82 275.3 15.6 4.7e-82 275.0 10.8 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Bac_luciferase PF00296.15 XP_011274822.1 - 1.9e-47 161.9 0.0 2.4e-47 161.5 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase CENP-N PF05238.8 XP_011274823.1 - 3.3e-83 279.9 3.0 3.9e-83 279.7 2.1 1.0 1 0 0 1 1 1 1 Kinetochore protein CHL4 like DUF4181 PF13789.1 XP_011274824.1 - 0.15 12.0 5.3 0.23 11.4 3.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4181) Vps16_N PF04841.8 XP_011274825.1 - 6.8e-70 235.6 0.9 1.2e-69 234.9 0.7 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.7 XP_011274825.1 - 4e-61 206.7 15.9 7.4e-61 205.8 11.0 1.4 1 0 0 1 1 1 1 Vps16, C-terminal region Skp1_POZ PF03931.10 XP_011274826.1 - 7.7e-18 64.3 0.0 5.3e-17 61.6 0.0 1.9 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain BTB PF00651.26 XP_011274826.1 - 0.0039 17.1 0.1 0.0054 16.7 0.1 1.4 1 1 0 1 1 1 1 BTB/POZ domain LAGLIDADG_1 PF00961.14 XP_011274826.1 - 0.076 13.5 0.0 0.085 13.4 0.0 1.2 1 0 0 1 1 1 0 LAGLIDADG endonuclease FOP_dimer PF09398.5 XP_011274826.1 - 0.11 12.5 0.1 0.18 11.7 0.0 1.4 1 1 0 1 1 1 0 FOP N terminal dimerisation domain Flocculin_t3 PF13928.1 XP_011274827.1 - 2.9e-12 46.5 25.0 2.9e-12 46.5 17.3 7.5 6 2 1 7 7 7 1 Flocculin type 3 repeat CLTH PF10607.4 XP_011274828.1 - 5.8e-26 90.9 4.7 5.8e-26 90.9 3.2 2.3 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 XP_011274828.1 - 2.9e-15 55.6 1.9 8.5e-15 54.1 1.3 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.1 XP_011274828.1 - 0.0021 17.8 0.6 0.0037 17.0 0.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 XP_011274828.1 - 0.018 15.0 0.2 0.04 13.9 0.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) La PF05383.12 XP_011274828.1 - 0.043 13.6 1.6 8.1 6.3 0.0 3.3 3 0 0 3 3 3 0 La domain zf-Nse PF11789.3 XP_011274828.1 - 0.051 13.0 2.0 0.12 11.9 1.4 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF164 PF02591.10 XP_011274828.1 - 0.075 12.8 0.1 0.19 11.5 0.1 1.6 1 0 0 1 1 1 0 Putative zinc ribbon domain Vma12 PF11712.3 XP_011274828.1 - 0.11 12.1 1.2 0.22 11.2 0.8 1.4 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Sgf11 PF08209.6 XP_011274829.1 - 4.7e-16 57.7 2.3 7e-16 57.2 1.6 1.3 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) zf-C2HC_2 PF13913.1 XP_011274829.1 - 0.096 12.3 0.5 0.14 11.8 0.4 1.3 1 0 0 1 1 1 0 zinc-finger of a C2HC-type tRNA_int_end_N2 PF12928.2 XP_011274830.1 - 1.3e-20 72.6 0.0 3.3e-20 71.3 0.0 1.7 2 0 0 2 2 2 1 tRNA-splicing endonuclease subunit sen54 N-term BRO1 PF03097.13 XP_011274831.1 - 1.3e-95 320.3 7.7 1.3e-95 320.3 5.3 2.2 2 1 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 XP_011274831.1 - 3e-37 128.1 34.9 7.4e-37 126.9 24.2 1.7 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Ceramidase PF05875.7 XP_011274832.1 - 1e-98 329.7 15.6 1.1e-98 329.5 10.8 1.0 1 0 0 1 1 1 1 Ceramidase PrgI PF12666.2 XP_011274832.1 - 5.8 7.1 7.3 1.9 8.6 0.2 3.1 1 1 2 3 3 3 0 PrgI family protein Glyco_hydro_32N PF00251.15 XP_011274833.1 - 2.8e-83 279.8 8.3 2.8e-83 279.8 5.8 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 XP_011274833.1 - 0.0037 17.6 0.1 0.039 14.3 0.0 2.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 C terminal Glyco_hydro_32N PF00251.15 XP_011274834.1 - 8e-74 248.7 11.0 1.2e-73 248.2 7.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 XP_011274834.1 - 9.4e-11 41.9 0.3 7.3e-09 35.8 0.0 2.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 C terminal Aldo_ket_red PF00248.16 XP_011274835.1 - 1.3e-40 139.0 0.0 1.4e-40 138.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF4451 PF14616.1 XP_011274836.1 - 8.3e-07 28.8 1.0 1.2e-06 28.2 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4451) DUF4451 PF14616.1 XP_011274837.1 - 4.6e-12 45.8 1.0 3.8e-06 26.6 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4451) DUF4451 PF14616.1 XP_011274838.1 - 2e-08 34.0 0.8 4.8e-08 32.8 0.6 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) Glyco_hydro_32N PF00251.15 XP_011274839.1 - 5.4e-83 278.8 6.6 7.5e-83 278.4 4.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 XP_011274839.1 - 4.7e-07 30.0 0.3 2.9e-06 27.5 0.1 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 C terminal Glyco_hydro_32N PF00251.15 XP_011274840.1 - 3.7e-81 272.8 10.5 3.7e-81 272.8 7.3 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 XP_011274840.1 - 4.6e-08 33.3 1.2 2.9e-06 27.5 0.2 2.7 2 1 0 2 2 2 1 Glycosyl hydrolases family 32 C terminal F-box-like PF12937.2 XP_011274841.1 - 0.049 13.3 0.0 0.096 12.4 0.0 1.5 1 0 0 1 1 1 0 F-box-like F-box PF00646.28 XP_011274842.1 - 0.01 15.4 0.0 0.063 12.9 0.0 2.3 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.2 XP_011274842.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 F-box-like Asp PF00026.18 XP_011274843.1 - 5e-38 131.1 3.9 5e-38 131.1 2.7 2.6 2 1 1 3 3 3 1 Eukaryotic aspartyl protease STAG PF08514.6 XP_011274844.1 - 2.8e-19 68.9 3.3 2.4e-18 65.9 2.3 2.7 1 1 0 1 1 1 1 STAG domain HEAT_2 PF13646.1 XP_011274844.1 - 0.0015 18.7 0.0 0.057 13.7 0.0 3.1 2 1 1 3 3 3 2 HEAT repeats HEAT PF02985.17 XP_011274844.1 - 0.0069 16.3 0.0 0.9 9.7 0.0 3.7 4 0 0 4 4 4 1 HEAT repeat zf-ZPR1 PF03367.8 XP_011274844.1 - 0.38 9.9 6.3 0.13 11.4 1.0 2.7 2 0 0 2 2 2 0 ZPR1 zinc-finger domain HSP70 PF00012.15 XP_011274845.1 - 1.2e-265 882.1 7.0 1.6e-265 881.7 4.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 XP_011274845.1 - 4.4e-15 55.0 0.0 7.2e-15 54.3 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein UPF0121 PF03661.8 XP_011274845.1 - 8e-13 48.1 2.1 1.2e-12 47.5 1.5 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) FGGY_C PF02782.11 XP_011274845.1 - 0.0054 16.3 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 XP_011274845.1 - 0.009 15.1 0.8 0.024 13.7 0.1 2.0 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase SHNi-TPR PF10516.4 XP_011274847.1 - 6.6e-17 60.4 2.0 2.2e-15 55.5 0.3 2.9 2 0 0 2 2 2 1 SHNi-TPR TPR_11 PF13414.1 XP_011274847.1 - 2.1e-06 27.2 0.9 0.063 12.9 0.1 2.7 2 1 1 3 3 3 2 TPR repeat TPR_2 PF07719.12 XP_011274847.1 - 6.8e-05 22.4 0.8 2.2 8.3 0.0 4.7 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 XP_011274847.1 - 0.0006 19.6 0.4 0.067 13.1 0.0 3.0 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 XP_011274847.1 - 0.031 13.8 0.2 20 5.0 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Trypan_PARP PF05887.6 XP_011274847.1 - 0.35 10.6 10.6 0.7 9.7 7.4 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Septin PF00735.13 XP_011274848.1 - 1.6e-117 391.5 0.5 1.6e-117 391.5 0.3 1.6 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 XP_011274848.1 - 3.6e-08 33.3 0.0 1.1e-07 31.8 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 XP_011274848.1 - 0.00013 21.2 0.3 0.001 18.2 0.2 2.3 1 1 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 XP_011274848.1 - 0.00036 20.0 3.2 0.0039 16.6 0.0 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AIG1 PF04548.11 XP_011274848.1 - 0.00077 18.6 0.0 0.00077 18.6 0.0 2.0 2 0 0 2 2 2 1 AIG1 family AAA_16 PF13191.1 XP_011274848.1 - 0.0038 17.2 1.8 0.075 13.0 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 XP_011274848.1 - 0.0059 16.7 0.2 0.051 13.7 0.0 2.7 1 1 1 2 2 2 1 AAA domain AAA_10 PF12846.2 XP_011274848.1 - 0.0082 15.6 0.1 0.1 12.0 0.0 2.1 2 0 0 2 2 2 1 AAA-like domain ABC_tran PF00005.22 XP_011274848.1 - 0.013 15.7 2.8 0.11 12.7 0.0 2.7 2 1 0 2 2 2 0 ABC transporter Dynamin_N PF00350.18 XP_011274848.1 - 0.032 14.0 8.5 2 8.2 0.0 3.5 2 1 1 3 3 3 0 Dynamin family Serglycin PF04360.7 XP_011274848.1 - 0.08 12.6 1.0 0.21 11.3 0.7 1.6 1 0 0 1 1 1 0 Serglycin IncA PF04156.9 XP_011274848.1 - 1.2 8.6 13.8 2 7.9 9.6 1.3 1 0 0 1 1 1 0 IncA protein YlqD PF11068.3 XP_011274848.1 - 7.8 6.5 15.8 17 5.4 11.0 1.5 1 0 0 1 1 1 0 YlqD protein E1-E2_ATPase PF00122.15 XP_011274849.1 - 1.1e-45 155.5 0.0 2.1e-45 154.5 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 XP_011274849.1 - 1.3e-39 136.8 0.1 2.2e-39 136.1 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 XP_011274849.1 - 2.2e-19 70.3 0.0 4.8e-19 69.2 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 XP_011274849.1 - 1.6e-15 57.0 21.2 1.3e-08 34.8 0.1 5.2 5 0 0 5 5 5 4 Heavy-metal-associated domain Hydrolase_3 PF08282.7 XP_011274849.1 - 2.3e-05 24.1 2.1 0.0059 16.2 0.1 3.2 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase GFA PF04828.9 XP_011274849.1 - 0.24 11.3 4.5 3.9 7.4 0.3 3.9 4 0 0 4 4 4 0 Glutathione-dependent formaldehyde-activating enzyme SAC3_GANP PF03399.11 XP_011274850.1 - 4.2e-24 85.2 6.6 5.8e-24 84.7 4.6 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 XP_011274850.1 - 3.4e-14 52.8 3.6 5.4e-14 52.1 2.5 1.3 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 VPS28 PF03997.7 XP_011274851.1 - 1.8e-60 203.7 0.0 2.2e-60 203.5 0.0 1.1 1 0 0 1 1 1 1 VPS28 protein DUF1301 PF06979.7 XP_011274851.1 - 0.012 15.7 0.1 0.02 15.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1301) ADH_zinc_N PF00107.21 XP_011274852.1 - 7.3e-29 99.9 0.0 1.1e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 XP_011274852.1 - 4.9e-10 40.3 0.0 9.4e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 XP_011274852.1 - 4.7e-09 35.9 0.0 9.3e-09 35.0 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_18 PF12847.2 XP_011274852.1 - 0.11 13.1 0.0 1.3 9.5 0.0 2.2 1 1 1 2 2 2 0 Methyltransferase domain RNA_polI_A14 PF08203.6 XP_011274853.1 - 0.022 14.9 0.4 1.2 9.3 0.1 2.9 3 0 0 3 3 3 0 Yeast RNA polymerase I subunit RPA14 Mob1_phocein PF03637.12 XP_011274853.1 - 0.056 13.1 1.7 0.074 12.7 0.2 1.9 2 0 0 2 2 2 0 Mob1/phocein family Arrestin_C PF02752.17 XP_011274854.1 - 2.4e-06 27.7 3.9 4e-06 26.9 0.5 2.4 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain GCR1_C PF12550.3 XP_011274855.1 - 0.0023 17.7 0.1 0.0067 16.2 0.1 1.7 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes DDHD PF02862.12 XP_011274855.1 - 2.4 7.9 13.1 3.9 7.1 9.1 1.3 1 0 0 1 1 1 0 DDHD domain DUF1031 PF06275.6 XP_011274856.1 - 0.14 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1031) DUF4451 PF14616.1 XP_011274857.1 - 6.8e-10 38.7 5.1 1.8e-09 37.3 3.5 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) DUF4451 PF14616.1 XP_011274858.1 - 3.8e-10 39.6 0.6 5.8e-10 39.0 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) DUF4451 PF14616.1 XP_011274859.1 - 1.6e-09 37.6 0.8 4.1e-09 36.2 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4451) PAT1 PF09770.4 XP_011274859.1 - 7.2 4.7 11.3 9.3 4.3 7.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 His_Phos_1 PF00300.17 XP_011274860.1 - 1.1e-22 80.8 0.1 1.4e-22 80.4 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Phage_C PF12025.3 XP_011274860.1 - 0.022 14.7 0.3 0.071 13.0 0.2 1.9 1 0 0 1 1 1 0 Phage protein C Peptidase_S49_N PF08496.5 XP_011274860.1 - 0.12 12.1 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Abhydrolase_6 PF12697.2 XP_011274862.1 - 1.4e-22 80.7 0.0 1.7e-22 80.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 XP_011274862.1 - 8.7e-13 48.2 0.0 1.6e-12 47.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 XP_011274862.1 - 2.1e-12 47.1 0.0 9.3e-12 44.9 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 XP_011274862.1 - 4.7e-05 23.0 0.0 8.5e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.3 XP_011274862.1 - 9.8e-05 22.1 0.0 0.0003 20.5 0.0 1.8 2 0 0 2 2 2 1 Putative lysophospholipase BAAT_C PF08840.6 XP_011274862.1 - 0.00028 20.6 0.0 0.0013 18.4 0.0 1.8 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF2305 PF10230.4 XP_011274862.1 - 0.0083 15.5 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) DUF900 PF05990.7 XP_011274862.1 - 0.037 13.3 0.2 6 6.1 0.0 2.5 3 0 0 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_2 PF02230.11 XP_011274862.1 - 0.048 13.1 0.3 4.7 6.5 0.0 2.4 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase Ser_hydrolase PF06821.8 XP_011274862.1 - 0.063 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase PAF-AH_p_II PF03403.8 XP_011274862.1 - 0.091 11.0 0.0 2.2 6.4 0.0 2.2 1 1 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Sugar_tr PF00083.19 XP_011274863.1 - 3.8e-114 381.7 27.6 4.3e-114 381.5 19.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 XP_011274863.1 - 8.4e-24 83.9 33.5 6.5e-20 71.1 9.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 XP_011274863.1 - 0.00023 19.6 23.2 0.0014 17.0 5.5 3.2 1 1 3 4 4 4 2 MFS/sugar transport protein TRI12 PF06609.8 XP_011274863.1 - 0.0076 14.4 4.9 0.097 10.8 1.6 2.2 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 XP_011274864.1 - 5.2e-114 381.3 22.5 6.3e-114 381.0 15.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 XP_011274864.1 - 1.3e-23 83.2 28.8 2.9e-17 62.4 5.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 XP_011274864.1 - 0.031 12.4 3.7 0.088 10.9 0.6 2.1 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) ABC2_membrane_2 PF12679.2 XP_011274864.1 - 1.2 7.9 7.0 0.5 9.1 2.2 2.2 1 1 1 2 2 2 0 ABC-2 family transporter protein Pantoate_ligase PF02569.10 XP_011274865.1 - 9.5e-90 300.1 0.1 1.1e-89 299.9 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase Cyt-b5 PF00173.23 XP_011274866.1 - 8.2e-09 35.1 0.0 1.3e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain MRP-L20 PF12824.2 XP_011274867.1 - 3.9e-37 127.7 1.1 4.9e-37 127.4 0.8 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 SRA1 PF07304.6 XP_011274867.1 - 0.12 12.1 0.1 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Steroid receptor RNA activator (SRA1) DUF1681 PF07933.9 XP_011274868.1 - 1.4e-11 44.1 0.0 2.1e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) NYD-SP28 PF14772.1 XP_011274868.1 - 0.029 14.4 0.6 0.05 13.7 0.4 1.3 1 0 0 1 1 1 0 Sperm tail HBS1_N PF08938.5 XP_011274869.1 - 2.9e-13 49.7 0.7 3.6e-13 49.4 0.5 1.1 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU PF00009.22 XP_011274870.1 - 6e-49 166.0 0.1 1.1e-48 165.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 XP_011274870.1 - 3.5e-08 33.3 0.2 2.1e-07 30.9 0.2 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 XP_011274870.1 - 9.5e-06 25.6 0.3 2.3e-05 24.4 0.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Miro PF08477.8 XP_011274870.1 - 3.7e-05 24.1 1.2 0.00037 20.9 0.0 3.1 2 1 0 2 2 2 1 Miro-like protein GTP_EFTU_D4 PF14578.1 XP_011274870.1 - 0.042 13.4 0.2 0.092 12.3 0.1 1.6 1 0 0 1 1 1 0 Elongation factor Tu domain 4 SNARE PF05739.14 XP_011274871.1 - 0.00063 19.3 2.7 0.00063 19.3 1.9 2.2 2 0 0 2 2 2 1 SNARE domain PTPS_related PF10131.4 XP_011274871.1 - 0.031 12.4 0.7 0.056 11.5 0.5 1.4 1 1 0 1 1 1 0 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein DUF721 PF05258.7 XP_011274871.1 - 0.068 13.3 0.2 0.13 12.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF721) Colicin-DNase PF12639.2 XP_011274871.1 - 0.64 10.2 3.1 11 6.3 0.1 2.4 2 0 0 2 2 2 0 DNase/tRNase domain of colicin-like bacteriocin Rabaptin PF03528.10 XP_011274871.1 - 4.4 7.2 12.0 0.026 14.4 2.0 2.1 2 1 0 2 2 2 0 Rabaptin DUF3887 PF13026.1 XP_011274871.1 - 4.9 7.4 10.4 0.37 11.0 1.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3887) Thymidylat_synt PF00303.14 XP_011274872.1 - 8.4e-119 395.5 0.0 9.6e-119 395.3 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase DUF4108 PF13390.1 XP_011274872.1 - 0.02 14.6 0.1 0.041 13.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4108) Shugoshin_N PF07558.6 XP_011274873.1 - 1.2e-09 37.6 5.3 4.3e-09 35.9 3.7 2.0 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.6 XP_011274873.1 - 2.7e-09 36.3 6.3 8.1e-09 34.7 4.3 1.9 1 0 0 1 1 1 1 Shugoshin C terminus NMO PF03060.10 XP_011274874.1 - 1.7e-68 231.2 0.0 2e-68 231.0 0.0 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 XP_011274874.1 - 5.8e-05 22.1 0.0 0.00035 19.5 0.0 1.9 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain QRPTase_C PF01729.14 XP_011274874.1 - 0.031 13.8 0.0 0.059 12.9 0.0 1.4 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain Sld5 PF05916.6 XP_011274875.1 - 2.2e-12 47.2 0.0 2.8e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 GINS complex protein Calici_PP_N PF08405.6 XP_011274875.1 - 0.038 12.8 0.2 0.044 12.6 0.1 1.1 1 0 0 1 1 1 0 Viral polyprotein N-terminal Rtt106 PF08512.7 XP_011274875.1 - 0.13 12.2 1.0 11 6.1 0.0 2.4 1 1 1 2 2 2 0 Histone chaperone Rttp106-like TPR_11 PF13414.1 XP_011274876.1 - 2.5e-38 129.5 18.0 1.1e-07 31.4 0.6 11.0 7 2 3 11 11 11 9 TPR repeat TPR_19 PF14559.1 XP_011274876.1 - 4.6e-29 100.5 7.9 7e-06 26.2 2.2 9.8 6 2 5 11 11 11 5 Tetratricopeptide repeat TPR_2 PF07719.12 XP_011274876.1 - 8.3e-29 97.1 16.7 0.002 17.9 0.3 13.4 14 0 0 14 14 14 6 Tetratricopeptide repeat TPR_12 PF13424.1 XP_011274876.1 - 1e-28 99.0 13.4 5.9e-06 26.1 0.1 10.3 8 2 2 11 11 11 5 Tetratricopeptide repeat TPR_16 PF13432.1 XP_011274876.1 - 3.3e-24 84.9 0.0 5.4e-05 23.7 0.4 9.1 7 1 3 10 10 10 4 Tetratricopeptide repeat TPR_1 PF00515.23 XP_011274876.1 - 4.7e-22 76.6 30.4 0.00018 20.9 0.0 12.7 14 0 0 14 14 14 4 Tetratricopeptide repeat TPR_14 PF13428.1 XP_011274876.1 - 3.5e-20 70.6 0.0 0.01 16.4 0.1 11.0 9 3 1 10 10 9 3 Tetratricopeptide repeat TPR_8 PF13181.1 XP_011274876.1 - 9.4e-19 65.7 42.3 0.0028 17.2 0.0 13.8 15 0 0 15 15 14 6 Tetratricopeptide repeat TPR_17 PF13431.1 XP_011274876.1 - 2.8e-16 58.2 2.3 1.8 8.9 0.0 10.1 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_6 PF13174.1 XP_011274876.1 - 3.1e-14 52.3 8.7 0.15 12.5 0.4 10.6 12 0 0 12 12 11 4 Tetratricopeptide repeat Apc3 PF12895.2 XP_011274876.1 - 6.4e-13 48.6 15.0 0.00055 20.0 0.3 7.5 5 1 1 7 7 7 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 XP_011274876.1 - 5.4e-12 44.5 10.3 0.024 14.3 0.0 9.0 9 1 0 9 9 9 2 Tetratricopeptide repeat TPR_9 PF13371.1 XP_011274876.1 - 3.8e-07 29.8 0.1 0.018 14.9 0.1 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 XP_011274876.1 - 4.1e-06 26.5 2.5 0.17 11.8 0.1 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 XP_011274876.1 - 0.0005 19.9 5.4 5.4 6.9 0.0 6.2 7 0 0 7 7 6 1 Fis1 C-terminal tetratricopeptide repeat TPR_3 PF07720.7 XP_011274876.1 - 0.01 15.6 13.3 0.39 10.5 0.1 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat DMRL_synthase PF00885.14 XP_011274878.1 - 7.3e-47 158.6 0.0 8.8e-47 158.4 0.0 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase Kunitz_legume PF00197.13 XP_011274879.1 - 0.051 13.1 0.2 0.051 13.1 0.2 2.9 3 1 1 4 4 4 0 Trypsin and protease inhibitor Hist_deacetyl PF00850.14 XP_011274880.1 - 1.6e-71 241.1 0.0 2.1e-71 240.7 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain MFS_1 PF07690.11 XP_011274881.1 - 2.1e-16 59.6 51.3 9.3e-16 57.4 32.2 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 XP_011274881.1 - 0.0044 15.2 22.8 0.0059 14.8 15.8 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4225 PF13988.1 XP_011274881.1 - 0.06 12.8 0.3 0.17 11.3 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4225) AAA PF00004.24 XP_011274883.1 - 4.3e-56 188.7 0.0 2.1e-43 147.7 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 XP_011274883.1 - 2.3e-07 31.6 0.1 0.0013 19.4 0.0 3.9 3 0 0 3 3 3 1 AAA domain AAA_2 PF07724.9 XP_011274883.1 - 1.9e-05 24.6 0.0 0.0033 17.3 0.0 3.1 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.1 XP_011274883.1 - 8.8e-05 21.9 0.1 0.0024 17.2 0.1 2.7 2 1 0 2 2 2 1 AAA domain Parvo_NS1 PF01057.12 XP_011274883.1 - 0.00011 21.2 0.0 0.00043 19.2 0.0 1.9 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_22 PF13401.1 XP_011274883.1 - 0.00013 22.0 0.0 0.0052 16.9 0.0 3.2 2 2 0 2 2 2 1 AAA domain RuvB_N PF05496.7 XP_011274883.1 - 0.00035 19.6 0.0 0.0014 17.7 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 XP_011274883.1 - 0.00069 19.7 0.0 0.009 16.1 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_16 PF13191.1 XP_011274883.1 - 0.00073 19.5 0.1 0.025 14.5 0.0 2.7 1 1 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.12 XP_011274883.1 - 0.00081 18.8 0.0 0.0019 17.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 XP_011274883.1 - 0.001 18.9 0.0 0.097 12.5 0.0 3.1 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 XP_011274883.1 - 0.0016 18.1 0.0 0.032 13.9 0.0 3.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 XP_011274883.1 - 0.0031 16.7 0.0 0.03 13.4 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 XP_011274883.1 - 0.0055 15.4 0.2 0.015 13.9 0.0 1.8 2 0 0 2 2 2 1 TIP49 C-terminus KaiC PF06745.8 XP_011274883.1 - 0.0074 15.4 0.1 0.035 13.2 0.0 2.2 2 0 0 2 2 2 1 KaiC AAA_19 PF13245.1 XP_011274883.1 - 0.0077 15.9 0.0 0.027 14.1 0.0 1.9 2 0 0 2 2 2 1 Part of AAA domain AAA_18 PF13238.1 XP_011274883.1 - 0.0085 16.3 0.0 0.071 13.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 XP_011274883.1 - 0.015 14.9 0.3 2 8.0 0.0 3.3 4 1 0 4 4 3 0 NACHT domain AAA_28 PF13521.1 XP_011274883.1 - 0.016 15.1 0.0 0.086 12.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain CDC48_N PF02359.13 XP_011274883.1 - 0.02 14.8 0.0 0.12 12.3 0.0 2.4 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), N-terminal domain PhoH PF02562.11 XP_011274883.1 - 0.039 13.1 0.0 0.11 11.7 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein AAA_33 PF13671.1 XP_011274883.1 - 0.052 13.4 0.0 0.25 11.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain GHMP_kinases_C PF08544.8 XP_011274883.1 - 0.17 12.0 0.0 0.82 9.9 0.0 2.2 1 0 0 1 1 1 0 GHMP kinases C terminal DnaJ PF00226.26 XP_011274884.1 - 3.7e-09 36.2 0.0 5.5e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 XP_011274884.1 - 0.00016 21.4 0.1 0.00016 21.4 0.1 1.2 1 0 0 1 1 1 1 Pam16 Diacid_rec PF05651.8 XP_011274884.1 - 0.005 16.2 0.0 0.0066 15.8 0.0 1.1 1 0 0 1 1 1 1 Putative sugar diacid recognition Osmo_CC PF08946.5 XP_011274884.1 - 0.87 9.6 4.3 11 6.1 0.0 2.6 2 1 0 2 2 2 0 Osmosensory transporter coiled coil zf-DHHC PF01529.15 XP_011274885.1 - 1.1e-34 119.3 10.4 1.1e-34 119.3 7.2 1.6 2 0 0 2 2 2 1 DHHC palmitoyltransferase IcmL PF11393.3 XP_011274885.1 - 0.08 12.8 0.5 0.15 12.0 0.3 1.4 1 0 0 1 1 1 0 Macrophage killing protein with similarity to conjugation protein DUF4064 PF13273.1 XP_011274885.1 - 0.24 11.5 7.4 5 7.2 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) DUF3611 PF12263.3 XP_011274885.1 - 1.8 7.9 7.1 1.5 8.2 0.4 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3611) FtsX PF02687.16 XP_011274885.1 - 3.2 7.5 12.7 22 4.8 2.2 2.9 2 1 1 3 3 3 0 FtsX-like permease family FtsH_ext PF06480.10 XP_011274885.1 - 3.6 7.7 6.4 0.64 10.2 1.4 2.0 2 0 0 2 2 2 0 FtsH Extracellular MFS_1 PF07690.11 XP_011274887.1 - 1.3e-11 43.8 2.2 1.3e-11 43.7 1.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 XP_011274887.1 - 3.8e-07 28.8 7.4 1.6e-06 26.8 5.5 1.6 1 1 1 2 2 2 1 MFS/sugar transport protein Sugar_tr PF00083.19 XP_011274887.1 - 0.00075 18.1 9.2 0.0011 17.6 6.4 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.2 XP_011274887.1 - 0.095 12.4 0.1 0.095 12.4 0.0 2.9 3 1 1 4 4 4 0 MFS_1 like family DUF1323 PF07037.6 XP_011274887.1 - 0.13 12.4 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative transcription regulator (DUF1323) MFS_1 PF07690.11 XP_011274888.1 - 7.4e-13 47.9 20.0 8.5e-13 47.7 13.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF749 PF05370.6 XP_011274889.1 - 0.14 12.0 5.3 2.7 8.0 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF749) PTR2 PF00854.16 XP_011274890.1 - 9.6e-41 139.7 7.6 1.4e-40 139.2 5.3 1.2 1 0 0 1 1 1 1 POT family MCH PF02289.11 XP_011274890.1 - 0.032 13.2 0.1 0.055 12.4 0.0 1.3 1 0 0 1 1 1 0 Cyclohydrolase (MCH) ubiquitin PF00240.18 XP_011274891.1 - 1.4e-34 117.2 0.9 2.7e-34 116.3 0.6 1.5 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.14 XP_011274891.1 - 7.2e-29 99.3 2.0 1.3e-28 98.5 1.4 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 XP_011274891.1 - 4.7e-20 71.0 0.7 1e-19 69.9 0.5 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 XP_011274891.1 - 8.8e-06 25.8 0.2 3.9e-05 23.8 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 XP_011274891.1 - 0.00012 21.8 0.0 0.00018 21.2 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 XP_011274891.1 - 0.0013 18.5 0.4 0.0028 17.5 0.3 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 XP_011274891.1 - 0.005 16.9 0.3 0.0068 16.5 0.2 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain IBR PF01485.16 XP_011274891.1 - 0.01 15.7 0.3 0.015 15.1 0.2 1.3 1 0 0 1 1 1 0 IBR domain DUF2870 PF11069.3 XP_011274891.1 - 0.068 13.2 0.2 0.14 12.2 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) zf-CGNR PF11706.3 XP_011274891.1 - 0.11 12.0 1.1 0.18 11.2 0.7 1.5 1 0 0 1 1 1 0 CGNR zinc finger Plexin_cytopl PF08337.7 XP_011274891.1 - 0.19 9.9 2.1 5.6 5.1 0.2 2.1 1 1 0 2 2 2 0 Plexin cytoplasmic RasGAP domain Phosducin PF02114.11 XP_011274892.1 - 6.7e-07 28.3 1.4 7.1e-07 28.2 1.0 1.1 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.15 XP_011274892.1 - 5.8e-05 22.7 0.0 0.0001 21.9 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin CENP-F_N PF10481.4 XP_011274892.1 - 0.028 13.7 0.4 3.8 6.8 0.0 2.1 2 0 0 2 2 2 0 Cenp-F N-terminal domain DnaG_DnaB_bind PF08278.6 XP_011274892.1 - 0.7 10.1 3.8 1.8 8.7 0.8 2.2 2 0 0 2 2 2 0 DNA primase DnaG DnaB-binding Sec10 PF07393.6 XP_011274893.1 - 4.3e-172 573.9 32.5 5.9e-172 573.5 22.5 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec10 Glyco_hydro_42 PF02449.10 XP_011274893.1 - 0.14 11.2 2.2 0.34 9.9 1.5 1.6 1 0 0 1 1 1 0 Beta-galactosidase HalX PF08663.5 XP_011274893.1 - 0.27 11.2 4.1 0.26 11.2 0.7 2.5 2 0 0 2 2 2 0 HalX domain Metallophos PF00149.23 XP_011274894.1 - 1.6e-16 60.3 1.6 2.8e-16 59.5 1.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RNase_T PF00929.19 XP_011274895.1 - 1.1e-13 51.7 0.8 2.7e-13 50.5 0.6 1.5 1 1 0 1 1 1 1 Exonuclease Hydrolase_6 PF13344.1 XP_011274895.1 - 0.084 12.7 0.0 0.14 12.0 0.0 1.5 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF2781 PF10914.3 XP_011274896.1 - 2.4e-10 40.4 0.9 2.5e-10 40.3 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) RNA_polI_A14 PF08203.6 XP_011274898.1 - 0.13 12.4 0.1 0.61 10.3 0.0 2.2 2 0 0 2 2 2 0 Yeast RNA polymerase I subunit RPA14 Pex2_Pex12 PF04757.9 XP_011274902.1 - 2.5e-49 167.7 10.4 3.5e-49 167.3 7.2 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.1 XP_011274902.1 - 2.9e-08 33.4 2.5 5.2e-08 32.6 1.8 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 XP_011274902.1 - 7.4e-07 29.0 1.8 1.2e-06 28.3 1.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 XP_011274902.1 - 0.00036 20.2 0.6 0.00064 19.5 0.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 XP_011274902.1 - 0.00044 19.8 0.9 0.0008 19.0 0.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 XP_011274902.1 - 0.0031 17.1 0.3 0.005 16.4 0.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF771 PF05595.6 XP_011274902.1 - 0.0038 17.1 1.2 0.0054 16.6 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF771) zf-RING_UBOX PF13445.1 XP_011274902.1 - 0.045 13.4 0.7 0.15 11.8 0.5 2.0 1 0 0 1 1 1 0 RING-type zinc-finger adh_short PF00106.20 XP_011274903.1 - 7.7e-20 71.4 0.0 9.5e-20 71.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 XP_011274903.1 - 4.8e-15 55.9 0.1 5.3e-15 55.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 XP_011274903.1 - 2.8e-11 43.4 0.0 3.5e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 XP_011274903.1 - 0.00017 21.6 0.0 0.00029 20.9 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding LRR_8 PF13855.1 XP_011274904.1 - 9.2e-05 22.1 5.4 3.5 7.4 0.0 5.5 6 1 0 6 6 6 3 Leucine rich repeat LRR_4 PF12799.2 XP_011274904.1 - 0.48 10.0 0.0 0.48 10.0 0.0 6.3 6 4 0 6 6 6 0 Leucine Rich repeats (2 copies) FTH PF01827.22 XP_011274905.1 - 0.002 17.7 4.5 0.002 17.7 3.1 4.2 4 2 1 5 5 5 1 FTH domain LRR_8 PF13855.1 XP_011274905.1 - 0.0021 17.7 15.8 11 5.9 0.0 7.2 7 2 0 7 7 7 4 Leucine rich repeat LRR_4 PF12799.2 XP_011274905.1 - 0.057 13.0 19.7 4.3 7.0 1.8 7.2 5 3 2 7 7 7 0 Leucine Rich repeats (2 copies) MatE PF01554.13 XP_011274906.1 - 9.3e-66 220.4 26.2 7.3e-35 119.9 5.9 2.2 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 XP_011274906.1 - 5.1e-05 23.0 5.6 5.1e-05 23.0 3.9 3.3 1 1 2 3 3 3 1 Polysaccharide biosynthesis C-terminal domain ADH_N PF08240.7 XP_011274907.1 - 3e-28 97.7 0.3 4.4e-28 97.2 0.2 1.2 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 XP_011274907.1 - 4.1e-18 65.1 0.0 6.6e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 XP_011274907.1 - 0.0079 15.8 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated FSH1 PF03959.8 XP_011274908.1 - 7.2e-62 208.5 0.0 8e-62 208.4 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 XP_011274908.1 - 0.00029 20.6 0.0 0.0004 20.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family ASL_C PF08328.6 XP_011274908.1 - 0.052 13.4 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminal Abhydrolase_2 PF02230.11 XP_011274908.1 - 0.057 12.8 0.0 0.094 12.1 0.0 1.5 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Nramp PF01566.13 XP_011274909.1 - 1.8e-94 316.4 14.5 1.8e-94 316.4 10.1 1.3 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein IgG_binding_B PF01378.12 XP_011274909.1 - 0.17 11.7 0.1 0.37 10.6 0.1 1.5 1 0 0 1 1 1 0 B domain Bac_luciferase PF00296.15 XP_011274910.1 - 8.5e-50 169.6 0.0 1.2e-49 169.1 0.0 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase FGGY_N PF00370.16 XP_011274911.1 - 2.3e-21 76.2 0.0 3.4e-14 52.7 0.0 3.1 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 XP_011274911.1 - 4.3e-13 49.3 0.0 1e-12 48.1 0.0 1.7 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain SPC12 PF06645.8 XP_011274912.1 - 9.5e-18 63.7 0.1 1e-17 63.6 0.0 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) Oxidored_q1 PF00361.15 XP_011274912.1 - 0.062 12.5 0.0 0.068 12.4 0.0 1.1 1 0 0 1 1 1 0 NADH-Ubiquinone/plastoquinone (complex I), various chains DUF4227 PF14004.1 XP_011274912.1 - 0.14 11.9 0.2 0.24 11.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4227) DUF1978 PF09321.5 XP_011274913.1 - 0.44 9.9 0.0 0.44 9.9 0.0 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF1978) FMN_bind_2 PF04299.7 XP_011274915.1 - 2.1e-52 177.0 0.0 2.6e-52 176.7 0.0 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain G6PD_C PF02781.11 XP_011274916.1 - 0.11 11.3 0.1 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate dehydrogenase, C-terminal domain N-SET PF11764.3 XP_011274920.1 - 4.2 7.2 5.6 13 5.6 3.9 1.8 1 1 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component N Aldo_ket_red PF00248.16 XP_011274921.1 - 2.8e-44 151.0 0.0 3.3e-44 150.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF4460 PF14687.1 XP_011274921.1 - 0.03 14.0 0.9 6.8 6.4 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4460) DUF3865 PF12981.2 XP_011274921.1 - 0.068 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3865) bZIP_1 PF00170.16 XP_011274922.1 - 3.7e-14 52.4 7.6 7.4e-14 51.4 5.3 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 XP_011274922.1 - 1.6e-10 40.6 8.3 2.7e-10 39.9 5.7 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 XP_011274922.1 - 0.012 15.9 3.5 0.021 15.1 2.4 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF4613 PF15390.1 XP_011274922.1 - 0.56 8.3 5.3 0.72 7.9 3.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Cupin_8 PF13621.1 XP_011274923.1 - 1.5e-09 37.7 0.0 4.9e-09 36.0 0.0 1.6 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 XP_011274923.1 - 5.2e-08 33.1 1.5 5.4e-06 26.6 0.0 3.5 3 1 0 3 3 3 1 JmjC domain, hydroxylase CGGC PF08821.6 XP_011274923.1 - 0.064 13.3 0.1 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 CGGC domain NMD3 PF04981.8 XP_011274923.1 - 0.093 11.8 0.4 0.16 11.0 0.2 1.3 1 0 0 1 1 1 0 NMD3 family Ribosomal_S18 PF01084.15 XP_011274924.1 - 3e-15 55.8 0.3 6.4e-15 54.7 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein S18 BCDHK_Adom3 PF10436.4 XP_011274925.1 - 3.9e-18 65.4 0.4 6e-18 64.8 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 XP_011274925.1 - 1.3e-16 60.2 0.1 2.6e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 XP_011274925.1 - 2e-05 24.2 0.1 4.7e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Rep_Org_C PF06926.6 XP_011274925.1 - 0.14 12.3 1.5 0.42 10.7 0.0 2.3 2 1 0 2 2 2 0 Putative replisome organiser protein C-terminus Transp_cyt_pur PF02133.10 XP_011274926.1 - 7.4e-69 232.3 34.3 9.3e-69 232.0 23.8 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin SAP PF02037.22 XP_011274928.1 - 4.1e-12 45.3 0.1 8.7e-12 44.2 0.1 1.6 1 0 0 1 1 1 1 SAP domain HNF-1_N PF04814.8 XP_011274928.1 - 0.97 9.5 9.9 1.2 9.1 6.8 1.2 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus CT47 PF15623.1 XP_011274928.1 - 1.4 8.6 22.6 1.7 8.3 15.6 1.1 1 0 0 1 1 1 0 Cancer/testis gene family 47 BNIP3 PF06553.7 XP_011274928.1 - 2.6 7.4 12.0 3.2 7.0 8.3 1.1 1 0 0 1 1 1 0 BNIP3 Neur_chan_memb PF02932.11 XP_011274928.1 - 2.7 7.8 9.0 3.3 7.5 6.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CDC45 PF02724.9 XP_011274928.1 - 4.3 5.2 15.8 4.9 5.0 10.9 1.0 1 0 0 1 1 1 0 CDC45-like protein AAR2 PF05282.6 XP_011274928.1 - 4.6 6.0 10.4 6 5.6 7.2 1.1 1 0 0 1 1 1 0 AAR2 protein Asp-B-Hydro_N PF05279.6 XP_011274928.1 - 4.7 6.9 24.3 6 6.6 16.8 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Apt1 PF10351.4 XP_011274928.1 - 4.8 5.9 13.3 6 5.6 9.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain RP-C_C PF11800.3 XP_011274928.1 - 5.4 6.6 9.9 7.1 6.2 6.9 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF2413 PF10310.4 XP_011274928.1 - 7.3 5.2 21.2 8.7 5.0 14.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Zip PF02535.17 XP_011274928.1 - 8 5.3 6.2 10 5.0 4.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter HSP70 PF00012.15 XP_011274928.1 - 9.6 3.9 15.8 11 3.7 11.0 1.1 1 0 0 1 1 1 0 Hsp70 protein RRM_6 PF14259.1 XP_011274929.1 - 4.4e-17 61.8 0.0 2.2e-13 49.9 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 XP_011274929.1 - 2.8e-15 55.6 0.0 2e-13 49.7 0.0 3.0 3 1 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 XP_011274929.1 - 5.9e-08 32.4 0.0 2.8e-07 30.2 0.0 2.2 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Vhr1 PF04001.8 XP_011274930.1 - 1.6e-43 146.4 1.3 1.6e-43 146.4 0.9 2.3 2 0 0 2 2 2 1 Transcription factor Vhr1 ICL PF00463.16 XP_011274931.1 - 7.4e-292 968.1 0.9 8.4e-292 968.0 0.6 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 XP_011274931.1 - 2.1e-12 46.7 0.0 5e-12 45.5 0.0 1.6 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase GST_C PF00043.20 XP_011274932.1 - 4.4e-21 74.6 0.0 6.9e-21 74.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 XP_011274932.1 - 1e-14 54.4 0.0 1.8e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 XP_011274932.1 - 5.4e-11 42.3 0.0 1.1e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 XP_011274932.1 - 5.1e-10 39.4 0.0 9.6e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 XP_011274932.1 - 0.00043 20.1 0.0 0.00075 19.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ERG4_ERG24 PF01222.12 XP_011274933.1 - 2.3e-151 504.2 10.5 2.6e-151 504.0 7.3 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 XP_011274933.1 - 9.5e-05 21.8 0.2 9.5e-05 21.8 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) DDE_Tnp_Tn3 PF01526.12 XP_011274933.1 - 0.093 11.3 0.0 0.15 10.6 0.0 1.2 1 0 0 1 1 1 0 Tn3 transposase DDE domain Med18 PF09637.5 XP_011274934.1 - 6.5e-47 160.1 6.8 7.9e-45 153.3 4.7 2.0 1 1 0 1 1 1 1 Med18 protein Pescadillo_N PF06732.6 XP_011274935.1 - 1.2e-120 402.0 0.9 1.2e-120 402.0 0.6 2.3 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.21 XP_011274935.1 - 5.5e-11 42.4 0.2 3.7e-10 39.8 0.0 2.5 2 1 1 3 3 3 1 BRCA1 C Terminus (BRCT) domain Rhomboid PF01694.17 XP_011274937.1 - 1.3e-26 93.4 16.9 1.3e-26 93.4 11.7 2.0 2 0 0 2 2 2 1 Rhomboid family DUF1751 PF08551.5 XP_011274937.1 - 0.71 10.2 4.4 0.36 11.1 0.3 2.3 2 1 0 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) Pkinase PF00069.20 XP_011274938.1 - 3.3e-48 164.0 0.0 1e-47 162.4 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011274938.1 - 6.9e-22 77.7 0.0 1.1e-21 77.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 XP_011274938.1 - 1.6e-08 33.8 0.0 7.4e-06 25.1 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 XP_011274938.1 - 0.18 10.8 0.0 0.29 10.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Endonuclease_NS PF01223.18 XP_011274940.1 - 3.9e-58 196.4 0.2 4.9e-58 196.1 0.1 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease HEAT PF02985.17 XP_011274942.1 - 0.042 13.9 0.0 20 5.5 0.0 3.7 2 0 0 2 2 2 0 HEAT repeat F-box-like PF12937.2 XP_011274943.1 - 9e-06 25.3 0.1 1.9e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 F-box-like EPSP_synthase PF00275.15 XP_011274945.1 - 2.6e-130 434.6 0.0 4.1e-130 433.9 0.0 1.3 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 XP_011274945.1 - 1.5e-99 332.1 0.0 6.2e-99 330.1 0.0 1.9 2 0 0 2 2 2 1 3-dehydroquinate synthase SKI PF01202.17 XP_011274945.1 - 1e-31 109.9 0.0 7.1e-31 107.2 0.0 2.3 2 0 0 2 2 2 1 Shikimate kinase DHquinase_I PF01487.10 XP_011274945.1 - 7.2e-29 101.0 0.0 2e-28 99.6 0.0 1.7 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.6 XP_011274945.1 - 1.1e-24 86.2 0.2 7.3e-23 80.4 0.0 2.8 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 XP_011274945.1 - 2.8e-14 53.3 0.0 1.2e-13 51.2 0.0 2.1 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 XP_011274945.1 - 8e-08 31.8 0.0 3.3e-07 29.8 0.0 2.1 2 1 0 2 2 2 1 Iron-containing alcohol dehydrogenase AAA_17 PF13207.1 XP_011274945.1 - 5.4e-07 30.4 0.3 3.5e-06 27.8 0.1 2.6 2 1 0 2 2 1 1 AAA domain Fe-ADH PF00465.14 XP_011274945.1 - 9.7e-06 24.4 0.5 0.00025 19.7 0.2 2.8 2 1 0 2 2 2 1 Iron-containing alcohol dehydrogenase AAA_14 PF13173.1 XP_011274945.1 - 0.0039 17.0 0.3 0.064 13.1 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.1 XP_011274945.1 - 0.005 16.7 0.0 0.017 15.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 XP_011274945.1 - 0.0098 16.2 3.1 0.032 14.5 0.1 3.1 3 0 0 3 3 3 1 AAA domain Pyr_redox PF00070.22 XP_011274945.1 - 0.072 13.4 1.6 6.2 7.3 0.0 2.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase RNase_H2_suC PF08615.6 XP_011274946.1 - 4e-06 26.6 0.2 0.00015 21.6 0.1 2.5 1 1 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Fungal_trans PF04082.13 XP_011274947.1 - 3.2e-36 124.5 3.4 3.2e-36 124.5 2.4 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 XP_011274947.1 - 1.5e-10 40.8 10.2 4.5e-10 39.2 7.1 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EF-hand_1 PF00036.27 XP_011274947.1 - 0.43 10.0 3.7 3.7 7.0 1.1 2.7 2 0 0 2 2 2 0 EF hand MFS_1 PF07690.11 XP_011274948.1 - 1.1e-24 86.8 17.5 2.4e-24 85.7 12.1 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily V_ATPase_I PF01496.14 XP_011274948.1 - 0.055 11.3 0.2 0.081 10.7 0.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4293 PF14126.1 XP_011274948.1 - 0.081 12.8 0.6 0.38 10.6 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) MFS_1 PF07690.11 XP_011274949.1 - 8.4e-24 83.9 16.6 1.3e-23 83.2 11.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.11 XP_011274950.1 - 2.8e-08 32.8 7.6 3.6e-08 32.5 5.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.11 XP_011274951.1 - 1.7e-11 43.4 2.0 2.1e-11 43.1 1.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily ParA PF10609.4 XP_011274953.1 - 2.5e-37 126.6 0.1 4.6e-37 125.7 0.0 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 XP_011274953.1 - 2.8e-17 62.7 0.0 4.6e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 XP_011274953.1 - 1.4e-08 34.1 0.0 2.7e-08 33.2 0.0 1.4 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.10 XP_011274953.1 - 1.2e-05 24.5 0.6 3.3e-05 23.0 0.1 1.8 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.1 XP_011274953.1 - 1.6e-05 24.8 0.0 0.00014 21.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 XP_011274953.1 - 0.0017 17.1 0.3 0.0025 16.6 0.2 1.2 1 0 0 1 1 1 1 ArgK protein APS_kinase PF01583.15 XP_011274953.1 - 0.025 14.2 0.1 0.046 13.3 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase YhjQ PF06564.7 XP_011274953.1 - 0.026 13.9 0.0 0.084 12.2 0.0 1.7 1 1 0 1 1 1 0 YhjQ protein AAA_25 PF13481.1 XP_011274953.1 - 0.045 13.1 0.1 0.082 12.2 0.1 1.3 1 0 0 1 1 1 0 AAA domain Fer4_NifH PF00142.13 XP_011274953.1 - 0.059 12.5 0.0 0.49 9.5 0.0 2.1 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family DUF258 PF03193.11 XP_011274953.1 - 0.15 11.2 0.2 0.34 10.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 2OG-FeII_Oxy_3 PF13640.1 XP_011274954.1 - 1.1e-11 45.0 0.2 1.7e-11 44.4 0.1 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 XP_011274954.1 - 1.8e-05 24.2 0.5 3.3e-05 23.4 0.3 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 XP_011274954.1 - 0.0024 18.1 0.1 0.0045 17.2 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FNIP PF05725.7 XP_011274955.1 - 0.062 13.2 4.0 2.8 7.9 0.4 2.7 2 0 0 2 2 2 0 FNIP Repeat OsmC PF02566.14 XP_011274955.1 - 0.091 12.9 0.4 0.17 12.1 0.3 1.4 1 0 0 1 1 1 0 OsmC-like protein NPV_P10 PF05531.7 XP_011274955.1 - 4.2 7.6 10.2 13 6.1 1.4 3.3 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein KH_1 PF00013.24 XP_011274956.1 - 0.15 11.7 0.1 0.29 10.8 0.1 1.4 1 0 0 1 1 1 0 KH domain Pex2_Pex12 PF04757.9 XP_011274957.1 - 5e-27 94.8 14.4 6.7e-27 94.3 10.0 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 XP_011274957.1 - 0.00011 22.1 6.6 0.00016 21.5 4.0 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 XP_011274957.1 - 0.00017 21.3 5.3 0.0003 20.5 3.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 XP_011274957.1 - 0.00041 20.1 2.1 0.00041 20.1 1.5 1.7 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 XP_011274957.1 - 0.00051 19.6 6.8 0.00093 18.8 4.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 XP_011274957.1 - 0.012 15.3 7.2 0.018 14.7 5.0 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 XP_011274957.1 - 0.012 15.2 3.2 0.031 13.9 2.2 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.20 XP_011274957.1 - 0.036 13.7 7.7 0.072 12.7 5.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 XP_011274957.1 - 1.7 8.8 5.6 3.1 7.9 3.6 1.6 1 1 0 1 1 1 0 RING-H2 zinc finger Tmemb_cc2 PF10267.4 XP_011274958.1 - 0.021 13.4 0.5 0.04 12.5 0.3 1.5 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein p450 PF00067.17 XP_011274959.1 - 4.7e-50 170.4 0.0 6.2e-50 170.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NifT PF06988.6 XP_011274960.1 - 0.045 13.2 0.5 0.16 11.4 0.4 1.9 1 0 0 1 1 1 0 NifT/FixU protein adh_short PF00106.20 XP_011274962.1 - 1.1e-11 44.8 0.0 1.5e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 XP_011274962.1 - 3.9e-08 33.3 0.1 5.5e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 XP_011274962.1 - 4.6e-05 23.1 0.0 6.8e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 XP_011274962.1 - 0.0021 17.0 0.1 0.0032 16.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 XP_011274962.1 - 0.017 15.1 0.0 0.026 14.6 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 XP_011274962.1 - 0.02 14.3 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 XP_011274962.1 - 0.032 14.2 0.1 0.076 13.0 0.0 1.6 1 1 0 1 1 1 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 XP_011274962.1 - 0.056 13.2 0.0 0.18 11.6 0.0 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 XP_011274962.1 - 0.058 12.4 0.0 0.096 11.7 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain adh_short PF00106.20 XP_011274963.1 - 3.2e-11 43.4 0.0 4.6e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 XP_011274963.1 - 4.2e-08 33.2 0.1 7.3e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 XP_011274963.1 - 3.1e-07 30.2 0.0 5.3e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 XP_011274963.1 - 0.00035 20.0 0.1 0.00059 19.3 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 XP_011274963.1 - 0.011 15.8 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 XP_011274963.1 - 0.021 13.7 0.2 0.03 13.2 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NmrA PF05368.8 XP_011274963.1 - 0.032 13.5 0.1 0.061 12.5 0.1 1.4 1 0 0 1 1 1 0 NmrA-like family NAD_binding_10 PF13460.1 XP_011274963.1 - 0.054 13.4 0.2 0.11 12.5 0.1 1.5 1 1 0 1 1 1 0 NADH(P)-binding DFP PF04127.10 XP_011274963.1 - 0.09 12.3 0.1 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein THF_DHG_CYH_C PF02882.14 XP_011274963.1 - 0.14 11.2 0.2 0.35 9.9 0.0 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain LRR_4 PF12799.2 XP_011274964.1 - 0.26 10.9 15.4 0.3 10.7 0.1 6.0 7 2 0 7 7 7 0 Leucine Rich repeats (2 copies) LRR_4 PF12799.2 XP_011274965.1 - 0.0032 17.0 24.6 0.04 13.5 1.2 6.3 4 3 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 XP_011274965.1 - 0.14 12.2 20.7 0.91 9.7 0.0 6.5 6 3 3 9 9 9 0 Leucine Rich repeat LRR_7 PF13504.1 XP_011274965.1 - 0.89 10.0 19.2 17 6.1 0.1 7.6 7 1 1 8 8 8 0 Leucine rich repeat LRR_1 PF00560.28 XP_011274965.1 - 1.3 9.2 17.6 5.3 7.4 0.1 6.1 7 0 0 7 7 7 0 Leucine Rich Repeat LRR_8 PF13855.1 XP_011274965.1 - 4.3 7.1 23.5 1.5 8.6 0.4 5.8 5 2 1 6 6 6 0 Leucine rich repeat LRR_8 PF13855.1 XP_011274966.1 - 0.0053 16.4 2.0 2.8 7.7 0.1 4.6 3 1 2 5 5 5 2 Leucine rich repeat LRR_4 PF12799.2 XP_011274966.1 - 0.035 13.7 9.9 0.053 13.1 0.1 5.3 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) F-box PF00646.28 XP_011274967.1 - 0.041 13.5 0.0 0.21 11.2 0.0 2.2 2 0 0 2 2 2 0 F-box domain PRANC PF09372.5 XP_011274969.1 - 0.23 11.4 3.5 7.2 6.6 0.1 2.7 1 1 1 2 2 2 0 PRANC domain MFS_1 PF07690.11 XP_011274971.1 - 1.7e-07 30.3 21.8 1.7e-07 30.3 15.1 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF754 PF05449.6 XP_011274971.1 - 0.12 12.3 5.0 0.044 13.8 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF754) MFS_1 PF07690.11 XP_011274972.1 - 4.6e-09 35.4 18.7 1.1e-08 34.1 12.9 1.6 1 0 0 1 1 1 1 Major Facilitator Superfamily E_raikovi_mat PF06360.6 XP_011274974.1 - 0.41 10.8 0.3 0.41 10.8 0.2 2.7 3 1 0 3 3 3 0 Euplotes raikovi mating pheromone LNS2 PF08235.8 XP_011274975.1 - 5.4e-73 243.7 0.0 8.9e-73 243.0 0.0 1.4 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 XP_011274975.1 - 3e-40 136.3 0.3 1e-39 134.6 0.0 2.0 2 0 0 2 2 2 1 lipin, N-terminal conserved region RRN3 PF05327.6 XP_011274976.1 - 4.8e-168 559.7 26.4 6.5e-168 559.3 18.3 1.1 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 TFIIA PF03153.8 XP_011274976.1 - 3e-05 24.1 9.8 3e-05 24.1 6.8 1.8 3 0 0 3 3 3 1 Transcription factor IIA, alpha/beta subunit SPRY PF00622.23 XP_011274977.1 - 7.3e-19 68.0 0.0 1.3e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 SPRY domain SRP-alpha_N PF04086.8 XP_011274977.1 - 8.9 5.5 21.6 13 5.0 15.0 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal SRP9-21 PF05486.7 XP_011274978.1 - 5e-20 71.0 0.3 5e-20 71.0 0.2 2.3 2 1 0 2 2 2 1 Signal recognition particle 9 kDa protein (SRP9) cwf18 PF08315.7 XP_011274978.1 - 5.1 7.5 12.1 0.8 10.1 2.8 2.1 1 1 1 2 2 2 0 cwf18 pre-mRNA splicing factor Kelch_2 PF07646.10 XP_011274979.1 - 0.09 12.5 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 Kelch motif F-box-like PF12937.2 XP_011274980.1 - 0.015 15.0 0.1 0.041 13.6 0.1 1.8 1 0 0 1 1 1 0 F-box-like Ninjurin PF04923.7 XP_011274982.1 - 1.6 8.5 6.9 2.7 7.7 0.6 3.0 2 1 1 3 3 3 0 Ninjurin PRP21_like_P PF12230.3 XP_011274983.1 - 2e-46 158.3 18.3 5.6e-24 84.9 3.5 3.1 2 1 1 3 3 3 2 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 XP_011274983.1 - 1.1e-26 92.2 8.7 2.3e-14 52.7 1.3 2.4 2 0 0 2 2 2 2 Surp module APH PF01636.18 XP_011274984.1 - 0.00016 21.5 0.0 0.00028 20.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 XP_011274984.1 - 0.00024 20.7 0.1 0.00024 20.7 0.1 3.2 4 0 0 4 4 4 1 Choline/ethanolamine kinase DnaA_N PF11638.3 XP_011274984.1 - 0.016 14.7 2.1 0.027 14.0 0.1 2.4 3 0 0 3 3 3 0 DnaA N-terminal domain Glyco_transf_34 PF05637.7 XP_011274985.1 - 7.7e-74 248.1 0.9 9.6e-74 247.8 0.7 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family EOS1 PF12326.3 XP_011274986.1 - 2.8e-52 176.3 6.9 5e-52 175.4 4.8 1.4 1 0 0 1 1 1 1 N-glycosylation protein TMEM51 PF15345.1 XP_011274986.1 - 0.75 9.4 3.1 0.8 9.3 0.8 1.6 1 1 1 2 2 2 0 Transmembrane protein 51 Ribosomal_S13 PF00416.17 XP_011274987.1 - 4.3e-21 75.3 0.0 5.3e-21 75.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 DNA_mis_repair PF01119.14 XP_011274988.1 - 2.6e-24 84.9 3.1 2.5e-23 81.7 0.4 2.6 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.6 XP_011274988.1 - 7.9e-24 83.8 0.3 2.4e-23 82.3 0.0 2.0 2 0 0 2 2 2 1 MutL C terminal dimerisation domain HATPase_c_3 PF13589.1 XP_011274988.1 - 1.6e-12 47.2 0.3 8.2e-12 44.9 0.2 2.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 XP_011274988.1 - 3.2e-09 36.4 0.1 7.2e-09 35.3 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Mito_carr PF00153.22 XP_011274989.1 - 5.4e-60 199.1 4.1 2.7e-19 68.6 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_6 PF13405.1 XP_011274989.1 - 3e-12 45.3 7.9 0.003 17.3 0.1 4.6 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.27 XP_011274989.1 - 3.7e-11 41.4 4.7 0.002 17.3 0.2 4.3 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 XP_011274989.1 - 3.1e-10 40.0 10.1 5e-07 29.7 1.5 2.7 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 XP_011274989.1 - 1.3e-05 24.7 2.0 0.0012 18.3 0.1 3.3 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 XP_011274989.1 - 0.0013 17.9 10.9 0.021 14.1 0.1 4.0 4 0 0 4 4 4 2 EF hand SPARC_Ca_bdg PF10591.4 XP_011274989.1 - 0.012 15.6 2.8 0.18 11.8 0.2 2.6 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region SinI PF08671.5 XP_011274989.1 - 0.13 11.7 0.2 0.52 9.7 0.0 2.1 2 0 0 2 2 2 0 Anti-repressor SinI adh_short PF00106.20 XP_011274990.1 - 3.4e-29 101.8 0.0 4.3e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 XP_011274990.1 - 2.6e-20 73.2 0.0 3.2e-20 72.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 XP_011274990.1 - 2.4e-08 33.8 0.0 3.4e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 XP_011274990.1 - 3.6e-05 23.0 0.1 0.00011 21.5 0.0 1.7 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 XP_011274990.1 - 0.12 12.2 0.1 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Abhydrolase_6 PF12697.2 XP_011274991.1 - 1.8e-23 83.6 0.0 2.4e-23 83.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 XP_011274991.1 - 2.5e-19 69.7 0.0 9.5e-18 64.5 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 XP_011274991.1 - 4.2e-12 46.0 0.0 1.5e-10 41.0 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 XP_011274991.1 - 0.00096 19.4 0.0 0.0022 18.2 0.0 1.5 2 0 0 2 2 2 1 Thioesterase domain DUF915 PF06028.6 XP_011274991.1 - 0.0012 17.9 0.3 0.09 11.8 0.0 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) DUF2305 PF10230.4 XP_011274991.1 - 0.0019 17.6 0.1 0.0026 17.2 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_3 PF07859.8 XP_011274991.1 - 0.0031 17.1 0.0 0.094 12.2 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 XP_011274991.1 - 0.0035 16.8 0.1 0.43 9.9 0.0 2.7 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase PGAP1 PF07819.8 XP_011274991.1 - 0.017 14.6 0.0 0.037 13.6 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein Peptidase_S9 PF00326.16 XP_011274991.1 - 0.038 13.1 0.0 9.4 5.3 0.0 2.9 3 0 0 3 3 3 0 Prolyl oligopeptidase family DLH PF01738.13 XP_011274991.1 - 0.049 12.8 0.0 1.9 7.6 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family FSH1 PF03959.8 XP_011274991.1 - 0.052 12.9 0.0 0.36 10.2 0.0 2.0 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Hydrolase_4 PF12146.3 XP_011274991.1 - 0.056 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase Ndr PF03096.9 XP_011274991.1 - 0.066 11.6 0.0 0.27 9.6 0.0 1.9 2 0 0 2 2 2 0 Ndr family Esterase PF00756.15 XP_011274991.1 - 0.088 12.2 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Peptidase_S15 PF02129.13 XP_011274991.1 - 0.098 12.0 0.0 0.52 9.6 0.0 2.0 3 0 0 3 3 3 0 X-Pro dipeptidyl-peptidase (S15 family) E1-E2_ATPase PF00122.15 XP_011274992.1 - 9.6e-66 221.1 4.9 1.9e-64 216.8 4.4 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 XP_011274992.1 - 3e-34 118.1 1.3 3e-34 118.1 0.9 2.6 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 XP_011274992.1 - 9.8e-28 98.0 0.0 7.7e-23 82.0 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 XP_011274992.1 - 3.4e-16 58.9 0.0 7.7e-16 57.8 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 XP_011274992.1 - 1e-14 55.1 0.2 2.2e-14 54.0 0.1 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 XP_011274992.1 - 3e-12 45.8 0.1 6.6e-12 44.7 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 XP_011274992.1 - 0.00059 19.4 0.8 0.027 14.0 0.4 2.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2628 PF10947.3 XP_011274992.1 - 5 6.9 13.0 0.19 11.5 0.1 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF2628) MFS_1 PF07690.11 XP_011274993.1 - 4.8e-39 134.0 37.8 4.8e-39 134.0 26.2 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily DSRB PF10781.4 XP_011274993.1 - 0.094 12.2 0.2 0.18 11.2 0.2 1.4 1 0 0 1 1 1 0 Dextransucrase DSRB Amidase PF01425.16 XP_011274994.1 - 4.9e-88 295.9 0.0 7.1e-88 295.3 0.0 1.2 1 0 0 1 1 1 1 Amidase AHS2 PF02626.10 XP_011274994.1 - 3.3e-85 285.6 0.0 1e-84 284.0 0.0 1.9 2 0 0 2 2 2 1 Allophanate hydrolase subunit 2 CPSase_L_D2 PF02786.12 XP_011274994.1 - 7.5e-55 185.4 0.0 1.4e-54 184.5 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain AHS1 PF02682.11 XP_011274994.1 - 8.6e-45 152.6 0.0 1.8e-44 151.6 0.0 1.5 1 0 0 1 1 1 1 Allophanate hydrolase subunit 1 CPSase_L_chain PF00289.17 XP_011274994.1 - 1.7e-37 127.9 0.0 6.8e-37 125.9 0.0 2.2 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 XP_011274994.1 - 6.3e-32 109.7 0.0 1.4e-31 108.6 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 XP_011274994.1 - 3.5e-18 64.9 2.7 1.1e-17 63.4 1.9 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 XP_011274994.1 - 8.9e-14 51.6 0.0 2.1e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain RnfC_N PF13375.1 XP_011274994.1 - 0.00016 21.2 0.1 0.00039 20.0 0.0 1.6 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain UvrD-helicase PF00580.16 XP_011274994.1 - 0.0028 17.0 0.0 0.0061 15.9 0.0 1.5 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain NQRA PF05896.6 XP_011274994.1 - 0.026 13.7 0.1 0.049 12.8 0.1 1.3 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) Biotin_lipoyl_2 PF13533.1 XP_011274994.1 - 2.1 8.0 6.8 9.9 5.9 0.2 3.0 2 1 1 3 3 3 0 Biotin-lipoyl like UCH PF00443.24 XP_011274995.1 - 4.2e-30 104.7 13.1 1.3e-29 103.1 3.9 2.5 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase BUD22 PF09073.5 XP_011274995.1 - 0.035 13.1 23.0 0.076 12.0 15.9 1.6 1 0 0 1 1 1 0 BUD22 Cyt-b5 PF00173.23 XP_011274996.1 - 3.3e-21 74.8 0.0 4.6e-21 74.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain HMG_box PF00505.14 XP_011274997.1 - 8.2e-22 77.2 12.4 3.7e-14 52.7 0.7 2.2 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.5 XP_011274997.1 - 4.4e-12 46.1 10.6 6.8e-06 26.3 2.3 2.3 2 0 0 2 2 2 2 HMG-box domain HMG_box_5 PF14887.1 XP_011274997.1 - 0.014 15.1 0.5 0.014 15.1 0.4 1.8 2 0 0 2 2 2 0 HMG (high mobility group) box 5 KRAB PF01352.22 XP_011274997.1 - 0.096 12.1 2.3 0.41 10.1 0.1 2.8 3 0 0 3 3 3 0 KRAB box Cu_amine_oxid PF01179.15 XP_011274998.1 - 2.4e-154 514.0 0.2 2.8e-154 513.7 0.1 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 XP_011274998.1 - 1e-08 35.1 0.3 2.8e-08 33.7 0.0 1.9 2 0 0 2 2 2 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.11 XP_011274998.1 - 0.00029 20.8 0.0 0.00057 19.9 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain dsDNA_bind PF01984.15 XP_011274999.1 - 2.5e-30 104.6 7.3 3.3e-30 104.2 5.0 1.1 1 0 0 1 1 1 1 Double-stranded DNA-binding domain SbcCD_C PF13558.1 XP_011274999.1 - 0.087 12.7 0.1 0.2 11.5 0.1 1.6 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit FliG_N PF14842.1 XP_011274999.1 - 0.17 11.9 1.0 4 7.5 0.1 2.2 1 1 0 2 2 2 0 FliG N-terminal domain zf-HC2 PF13490.1 XP_011274999.1 - 0.31 11.0 1.9 0.34 10.8 0.1 1.9 2 0 0 2 2 2 0 Putative zinc-finger Solute_trans_a PF03619.11 XP_011275000.1 - 8.6e-87 290.9 5.6 1.1e-86 290.5 3.9 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF2104 PF09877.4 XP_011275000.1 - 0.028 14.3 0.2 0.15 12.0 0.0 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2104) FG-GAP PF01839.18 XP_011275001.1 - 0.00083 18.9 6.2 0.0034 17.0 0.1 3.8 3 0 0 3 3 3 1 FG-GAP repeat FG-GAP_2 PF14312.1 XP_011275001.1 - 0.0033 17.4 5.4 7.3 6.6 0.0 5.2 6 0 0 6 6 6 2 FG-GAP repeat VCBS PF13517.1 XP_011275001.1 - 0.0042 17.3 0.0 0.0042 17.3 0.0 2.7 3 0 0 3 3 3 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella mIF3 PF14877.1 XP_011275002.1 - 3.3e-26 91.7 6.9 3.3e-26 91.7 4.8 2.4 2 1 1 3 3 3 1 Mitochondrial translation initiation factor Big_4 PF07532.6 XP_011275002.1 - 0.05 13.1 0.2 0.11 11.9 0.1 1.6 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 4) PNGaseA PF12222.3 XP_011275003.1 - 1.2e-58 199.0 8.2 2.3e-58 198.0 5.7 1.5 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A DltD_N PF04915.7 XP_011275003.1 - 0.074 12.9 1.9 0.57 10.0 0.1 2.8 3 0 0 3 3 3 0 DltD N-terminal region Mito_carr PF00153.22 XP_011275004.1 - 3e-69 228.7 2.1 2.9e-23 81.4 0.1 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein 2-Hacid_dh_C PF02826.14 XP_011275005.1 - 7e-56 188.1 0.0 3.4e-55 185.9 0.0 1.9 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 XP_011275005.1 - 1.1e-13 50.8 0.0 1.6e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 XP_011275005.1 - 0.00037 20.3 0.1 0.0021 17.9 0.0 2.2 3 0 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 XP_011275005.1 - 0.003 17.6 0.0 0.0091 16.1 0.0 1.8 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase IlvN PF07991.7 XP_011275005.1 - 0.017 14.4 0.0 0.087 12.1 0.0 1.9 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain ThiF PF00899.16 XP_011275005.1 - 0.064 13.0 0.1 0.27 11.0 0.0 2.1 2 0 0 2 2 2 0 ThiF family Nha1_C PF08619.5 XP_011275006.1 - 1.5e-80 271.6 40.8 1.5e-80 271.6 28.3 1.5 2 0 0 2 2 2 1 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.16 XP_011275006.1 - 2.4e-75 253.4 28.9 2.9e-75 253.1 20.1 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family AA_permease PF00324.16 XP_011275007.1 - 3.3e-81 273.0 31.9 4.7e-81 272.5 22.1 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 XP_011275007.1 - 8.7e-23 80.5 35.2 1.5e-22 79.7 24.4 1.3 1 0 0 1 1 1 1 Amino acid permease DUF3278 PF11683.3 XP_011275007.1 - 0.027 14.4 1.6 5.7 6.9 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) MgtE PF01769.11 XP_011275007.1 - 0.055 13.7 0.0 0.055 13.7 0.0 3.6 4 0 0 4 4 4 0 Divalent cation transporter DeoRC PF00455.17 XP_011275007.1 - 0.12 11.9 0.1 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 DeoR C terminal sensor domain ELH PF02323.10 XP_011275007.1 - 1.6 7.7 7.9 0.13 11.3 2.1 1.6 2 0 0 2 2 2 0 Egg-laying hormone precursor ADK PF00406.17 XP_011275008.1 - 2e-42 144.6 0.0 2.3e-42 144.3 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 XP_011275008.1 - 1.5e-13 50.1 0.0 2.8e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.1 XP_011275008.1 - 3.7e-05 24.0 0.0 0.00011 22.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 XP_011275008.1 - 0.00043 21.0 0.0 0.0027 18.5 0.0 1.9 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 XP_011275008.1 - 0.0035 17.2 0.4 0.03 14.2 0.3 2.1 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 XP_011275008.1 - 0.013 14.6 0.0 0.02 13.9 0.0 1.5 1 1 0 1 1 1 0 Zeta toxin TPR_11 PF13414.1 XP_011275009.1 - 3.8e-43 144.9 23.9 3.4e-07 29.8 0.0 11.4 8 2 4 12 12 12 11 TPR repeat TPR_16 PF13432.1 XP_011275009.1 - 7e-35 118.9 20.5 2.8e-06 27.8 0.0 12.0 10 2 2 12 12 12 6 Tetratricopeptide repeat TPR_19 PF14559.1 XP_011275009.1 - 5.3e-30 103.5 17.0 1.5e-09 38.0 0.0 12.0 10 5 4 14 14 13 5 Tetratricopeptide repeat TPR_2 PF07719.12 XP_011275009.1 - 5.6e-28 94.5 29.4 1.6e-06 27.6 0.0 14.7 16 0 0 16 16 15 4 Tetratricopeptide repeat TPR_14 PF13428.1 XP_011275009.1 - 2.5e-27 92.8 26.4 4.2e-05 23.8 0.0 15.5 12 4 6 18 18 15 6 Tetratricopeptide repeat TPR_17 PF13431.1 XP_011275009.1 - 7.6e-27 91.2 8.5 0.0054 16.8 0.0 12.6 13 0 0 13 13 12 6 Tetratricopeptide repeat TPR_1 PF00515.23 XP_011275009.1 - 5.9e-23 79.4 24.0 1e-06 28.1 0.0 11.8 12 1 0 12 12 12 5 Tetratricopeptide repeat TPR_12 PF13424.1 XP_011275009.1 - 4.6e-20 71.3 23.4 0.00087 19.1 0.1 10.7 8 3 5 13 13 13 7 Tetratricopeptide repeat TPR_8 PF13181.1 XP_011275009.1 - 8.7e-16 56.4 27.8 0.0029 17.2 0.0 10.4 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_6 PF13174.1 XP_011275009.1 - 1.8e-14 53.1 7.8 1.1 9.8 0.0 11.5 12 0 0 12 12 10 2 Tetratricopeptide repeat TPR_9 PF13371.1 XP_011275009.1 - 1.1e-11 44.4 0.4 0.0023 17.7 0.0 4.7 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 XP_011275009.1 - 3e-09 35.9 7.0 0.16 11.8 0.0 9.6 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_4 PF07721.9 XP_011275009.1 - 2.4e-06 27.4 0.5 0.78 10.3 0.2 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 XP_011275009.1 - 6.5e-06 25.9 1.4 0.34 10.8 0.0 6.4 6 1 1 7 7 7 2 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.1 XP_011275009.1 - 0.00032 20.5 0.0 14 5.7 0.0 4.5 3 0 0 3 3 3 0 Tetratricopeptide repeat MutS_V PF00488.16 XP_011275010.1 - 1.7e-76 256.7 0.1 2.6e-76 256.1 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 XP_011275010.1 - 8.8e-46 156.2 0.3 1.7e-45 155.3 0.2 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 XP_011275010.1 - 1.3e-32 112.1 0.0 3.3e-32 110.8 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 XP_011275010.1 - 2.7e-16 59.8 0.1 1.4e-15 57.5 0.0 2.3 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 XP_011275010.1 - 4.7e-10 39.5 0.3 1.8e-09 37.6 0.2 2.1 1 0 0 1 1 1 1 MutS family domain IV AAA_29 PF13555.1 XP_011275010.1 - 0.069 12.6 0.2 0.19 11.2 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain JmjC PF02373.17 XP_011275011.1 - 2.8e-38 130.6 2.0 1e-37 128.8 0.2 2.7 3 0 0 3 3 3 1 JmjC domain, hydroxylase zf-HC5HC2H PF13771.1 XP_011275011.1 - 5.1e-16 58.5 4.8 5.1e-16 58.5 3.3 2.0 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 XP_011275011.1 - 2.2e-15 56.6 5.3 1e-14 54.4 3.4 2.1 1 1 0 1 1 1 1 PHD-zinc-finger like domain JmjN PF02375.12 XP_011275011.1 - 2.9e-15 55.4 0.8 6.6e-15 54.3 0.6 1.7 1 0 0 1 1 1 1 jmjN domain PHD PF00628.24 XP_011275011.1 - 0.14 11.8 8.2 0.35 10.5 5.7 1.7 1 0 0 1 1 1 0 PHD-finger Rad17 PF03215.10 XP_011275012.1 - 1.2e-66 225.5 6.7 6.7e-53 180.1 0.8 2.9 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein NOP5NT PF08156.8 XP_011275012.1 - 0.065 13.3 0.3 0.065 13.3 0.2 3.2 3 0 0 3 3 3 0 NOP5NT (NUC127) domain Glutaredoxin PF00462.19 XP_011275013.1 - 2.1e-18 66.0 0.0 9.6e-18 63.9 0.0 2.1 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 XP_011275013.1 - 1.7e-13 50.1 0.0 3.8e-13 49.0 0.0 1.5 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.1 XP_011275013.1 - 1.8e-05 24.7 0.0 0.0006 19.8 0.0 2.4 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.1 XP_011275013.1 - 0.0081 15.7 0.1 0.083 12.4 0.1 2.3 2 1 1 3 3 3 1 Thioredoxin Methyltransf_11 PF08241.7 XP_011275014.1 - 7.5e-21 74.4 0.0 1.6e-20 73.3 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 XP_011275014.1 - 7.2e-13 48.3 0.0 1.4e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 XP_011275014.1 - 3.8e-12 46.5 0.0 3e-11 43.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 XP_011275014.1 - 7.6e-12 44.8 0.0 3.2e-11 42.7 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 XP_011275014.1 - 4.4e-11 43.0 0.0 9.1e-11 42.0 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 XP_011275014.1 - 9.7e-10 39.0 0.0 3e-09 37.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 XP_011275014.1 - 2.7e-09 36.9 0.0 3.7e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 XP_011275014.1 - 6e-06 26.2 0.0 1.2e-05 25.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.6 XP_011275014.1 - 0.0015 17.3 0.0 0.0023 16.6 0.0 1.3 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_8 PF05148.10 XP_011275014.1 - 0.0018 17.9 0.0 0.016 14.8 0.0 2.0 2 0 0 2 2 2 1 Hypothetical methyltransferase DUF2414 PF10309.4 XP_011275014.1 - 0.017 14.7 0.2 0.79 9.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2414) DREV PF05219.7 XP_011275014.1 - 0.018 13.9 0.0 0.029 13.2 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase FtsJ PF01728.14 XP_011275014.1 - 0.025 14.5 0.0 0.036 14.0 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase CMAS PF02353.15 XP_011275014.1 - 0.035 13.1 0.0 0.084 11.9 0.0 1.5 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase MTS PF05175.9 XP_011275014.1 - 0.081 12.2 0.0 0.23 10.8 0.0 1.7 2 1 0 2 2 2 0 Methyltransferase small domain Methyltransf_11 PF08241.7 XP_011275015.1 - 5.9e-20 71.5 0.0 2.8e-19 69.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 XP_011275015.1 - 8.6e-16 57.8 0.0 2.7e-15 56.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 XP_011275015.1 - 4.9e-12 46.1 0.0 7.5e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 XP_011275015.1 - 2.4e-11 43.1 0.0 3.9e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 XP_011275015.1 - 8.7e-10 38.8 0.0 1.5e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 XP_011275015.1 - 2.4e-09 37.7 0.0 4.7e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 XP_011275015.1 - 5.9e-08 32.5 0.0 1.1e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 XP_011275015.1 - 5.6e-05 23.1 0.0 0.00023 21.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 XP_011275015.1 - 0.00014 20.9 0.0 0.00044 19.3 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase PCMT PF01135.14 XP_011275015.1 - 0.0013 18.3 0.0 0.0025 17.3 0.0 1.4 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 XP_011275015.1 - 0.0017 17.7 0.0 0.0029 16.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.1 XP_011275015.1 - 0.006 16.2 0.0 0.0095 15.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 XP_011275015.1 - 0.017 13.8 0.1 0.04 12.6 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) Methyltransf_8 PF05148.10 XP_011275015.1 - 0.019 14.6 0.0 0.087 12.4 0.0 1.9 1 1 0 1 1 1 0 Hypothetical methyltransferase DREV PF05219.7 XP_011275015.1 - 0.035 12.9 0.0 0.17 10.7 0.0 1.8 1 1 1 2 2 2 0 DREV methyltransferase RrnaAD PF00398.15 XP_011275015.1 - 0.066 12.2 0.0 0.086 11.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Candida_ALS_N PF11766.3 XP_011275016.1 - 4.5e-57 192.8 7.0 4.5e-57 192.8 4.9 4.0 2 0 0 2 2 2 1 Cell-wall agglutinin N-terminal ligand-sugar binding Na_H_Exchanger PF00999.16 XP_011275017.1 - 6.1e-63 212.6 25.7 7e-63 212.4 17.8 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.1 XP_011275017.1 - 5e-05 23.1 0.1 0.00057 19.7 0.0 2.7 2 0 0 2 2 2 1 YrhC-like protein Nha1_C PF08619.5 XP_011275017.1 - 0.011 15.0 1.1 0.015 14.6 0.8 1.1 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus BAR_2 PF10455.4 XP_011275018.1 - 5.9e-74 248.5 13.7 1.1e-73 247.6 9.5 1.5 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 XP_011275018.1 - 2.1e-16 60.1 10.3 1.4e-15 57.4 7.1 2.0 1 1 0 1 1 1 1 BAR domain P22_AR_C PF10548.4 XP_011275018.1 - 0.039 13.8 0.1 0.56 10.1 0.0 2.6 2 0 0 2 2 2 0 P22AR C-terminal domain ApoLp-III PF07464.6 XP_011275018.1 - 0.067 13.2 15.7 0.24 11.4 0.1 3.6 1 1 3 4 4 4 0 Apolipophorin-III precursor (apoLp-III) DUF733 PF05306.6 XP_011275018.1 - 0.11 12.8 2.8 0.12 12.7 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF733) DUF2935 PF11155.3 XP_011275018.1 - 0.16 12.0 3.5 4.3 7.4 0.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) PEP-utilisers_N PF05524.8 XP_011275018.1 - 2.7 7.8 7.0 1.2 8.9 1.8 2.5 1 1 2 3 3 3 0 PEP-utilising enzyme, N-terminal Ofd1_CTDD PF10637.4 XP_011275019.1 - 1.1e-93 313.2 2.2 4.6e-90 301.3 1.8 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 XP_011275019.1 - 1.2e-14 54.6 0.0 3.2e-14 53.2 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF1355 PF07090.6 XP_011275019.1 - 0.06 12.7 0.9 6.2 6.1 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1355) Complex1_LYR_1 PF13232.1 XP_011275020.1 - 1.8e-20 72.8 4.1 2.4e-20 72.4 2.8 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 XP_011275020.1 - 8.1e-19 67.1 3.8 1.3e-18 66.5 2.7 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) UPF0058 PF01893.11 XP_011275020.1 - 0.035 14.1 0.2 3.8 7.6 0.2 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0058 UN_NPL4 PF11543.3 XP_011275020.1 - 0.14 12.4 1.3 2.9 8.2 0.1 2.0 1 1 1 2 2 2 0 Nuclear pore localisation protein NPL4 Complex1_LYR_2 PF13233.1 XP_011275020.1 - 0.21 12.0 2.3 0.25 11.8 1.6 1.2 1 0 0 1 1 1 0 Complex1_LYR-like Apq12 PF12716.2 XP_011275021.1 - 0.00017 21.2 11.5 0.00017 21.2 8.0 1.9 2 0 0 2 2 2 1 Nuclear pore assembly and biogenesis Polysacc_synt_C PF14667.1 XP_011275021.1 - 0.0008 19.2 7.9 0.0011 18.8 5.4 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis C-terminal domain DUF998 PF06197.8 XP_011275021.1 - 0.16 11.2 6.7 0.22 10.8 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF998) DUF1282 PF06930.7 XP_011275021.1 - 0.39 10.3 8.5 0.51 9.9 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) Phageshock_PspG PF09583.5 XP_011275021.1 - 6 7.0 11.1 1 9.5 4.4 2.0 2 0 0 2 2 2 0 Phage shock protein G (Phageshock_PspG) DnaJ-X PF14308.1 XP_011275022.1 - 4.5e-72 241.6 11.9 4.5e-72 241.6 8.2 1.9 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.26 XP_011275022.1 - 2.2e-25 88.1 3.4 4.3e-25 87.2 1.4 2.3 2 0 0 2 2 2 1 DnaJ domain AAA PF00004.24 XP_011275023.1 - 6.7e-39 133.1 0.0 1.8e-38 131.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 XP_011275023.1 - 3.5e-06 27.1 0.3 0.00019 21.5 0.1 3.2 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 XP_011275023.1 - 1.1e-05 25.4 0.7 0.013 15.5 0.1 3.5 3 1 0 3 3 3 1 AAA ATPase domain Vps4_C PF09336.5 XP_011275023.1 - 2.7e-05 23.9 0.0 0.00093 19.0 0.0 2.8 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_2 PF07724.9 XP_011275023.1 - 3.4e-05 23.8 0.1 0.00051 19.9 0.0 2.7 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 XP_011275023.1 - 4e-05 22.7 0.0 0.00012 21.2 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 XP_011275023.1 - 0.00045 19.9 0.0 0.0015 18.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 XP_011275023.1 - 0.0013 17.5 2.1 0.0028 16.4 0.0 2.1 2 0 0 2 2 2 1 TIP49 C-terminus DUF815 PF05673.8 XP_011275023.1 - 0.0014 17.6 0.0 0.0028 16.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.12 XP_011275023.1 - 0.0017 17.8 0.0 0.0038 16.6 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 XP_011275023.1 - 0.0038 16.4 0.1 0.009 15.1 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 XP_011275023.1 - 0.0068 16.3 0.0 0.04 13.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 XP_011275023.1 - 0.022 14.1 0.1 0.16 11.3 0.0 2.2 1 1 0 2 2 2 0 AAA domain AAA_17 PF13207.1 XP_011275023.1 - 0.039 14.7 0.7 0.17 12.7 0.0 2.4 2 1 0 2 2 2 0 AAA domain NACHT PF05729.7 XP_011275023.1 - 0.039 13.6 0.2 0.34 10.5 0.0 2.7 2 1 1 3 3 3 0 NACHT domain AAA_33 PF13671.1 XP_011275023.1 - 0.039 13.8 0.0 0.039 13.8 0.0 2.5 3 0 0 3 3 3 0 AAA domain DUF4596 PF15363.1 XP_011275023.1 - 1.8 8.5 12.1 1.4 8.9 1.0 3.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4596) Metallophos PF00149.23 XP_011275024.1 - 1.3e-25 89.9 6.2 2.5e-25 89.0 4.3 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase HAD PF12710.2 XP_011275025.1 - 3.4e-14 53.4 0.0 1.1e-13 51.8 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 XP_011275025.1 - 8.1e-14 51.2 0.0 8.1e-14 51.2 0.0 2.2 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 XP_011275025.1 - 1.2e-12 47.5 0.0 3.9e-12 45.9 0.0 1.9 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 XP_011275025.1 - 7.2e-12 46.1 1.7 3.4e-10 40.7 1.2 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 XP_011275025.1 - 0.0025 17.4 0.2 0.0025 17.4 0.2 3.4 4 0 0 4 4 4 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 XP_011275025.1 - 0.053 13.7 0.0 0.26 11.4 0.1 2.1 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Hemerythrin PF01814.18 XP_011275026.1 - 0.049 13.7 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain PolyA_pol PF01743.15 XP_011275027.1 - 3.1e-28 98.4 0.3 7.4e-28 97.2 0.1 1.8 2 0 0 2 2 2 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 XP_011275027.1 - 9.2e-13 47.5 0.2 2.9e-12 45.9 0.0 1.9 2 0 0 2 2 2 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.1 XP_011275027.1 - 0.0001 22.1 0.2 0.00041 20.1 0.1 2.1 1 1 0 1 1 1 1 tRNA nucleotidyltransferase domain 2 putative Sec63 PF02889.11 XP_011275028.1 - 7e-185 613.5 14.1 6.7e-97 324.4 0.1 2.7 3 0 0 3 3 3 2 Sec63 Brl domain DEAD PF00270.24 XP_011275028.1 - 3.8e-45 153.4 0.0 4.1e-29 101.2 0.0 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 XP_011275028.1 - 1.2e-13 51.3 0.1 4.1e-10 39.7 0.0 2.9 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 XP_011275028.1 - 2.8e-08 33.5 0.0 2.4e-07 30.5 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 XP_011275028.1 - 5.3e-06 26.5 0.1 0.038 14.1 0.0 3.4 3 0 0 3 3 3 2 AAA domain SNF2_N PF00176.18 XP_011275028.1 - 2.5e-05 23.2 0.0 0.0007 18.4 0.0 2.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain AAA_19 PF13245.1 XP_011275028.1 - 0.0021 17.8 0.0 0.83 9.4 0.0 2.6 2 0 0 2 2 2 2 Part of AAA domain PhoH PF02562.11 XP_011275028.1 - 0.003 16.7 0.0 1.8 7.7 0.0 2.6 2 0 0 2 2 2 2 PhoH-like protein IstB_IS21 PF01695.12 XP_011275028.1 - 0.014 14.7 0.0 1.7 8.0 0.0 3.7 5 0 0 5 5 5 0 IstB-like ATP binding protein DUF1227 PF06777.6 XP_011275029.1 - 3.2e-61 205.3 2.3 3.2e-61 205.3 1.6 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 XP_011275029.1 - 2.5e-50 170.2 1.6 6e-50 169.0 1.1 1.7 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 XP_011275029.1 - 1.5e-44 151.8 0.0 5.2e-44 150.1 0.0 1.9 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD PF00270.24 XP_011275029.1 - 0.0016 17.9 0.2 0.98 8.8 0.0 2.8 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.10 XP_011275029.1 - 0.0075 16.1 0.1 2.5 7.8 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit SNF2_N PF00176.18 XP_011275029.1 - 0.012 14.3 0.1 0.48 9.1 0.0 2.2 2 0 0 2 2 2 0 SNF2 family N-terminal domain EMP24_GP25L PF01105.19 XP_011275030.1 - 1.9e-43 148.3 0.2 2.2e-43 148.1 0.1 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Ribosomal_S27e PF01667.12 XP_011275031.1 - 7.6e-29 99.0 0.9 1e-28 98.6 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein S27 TF_Zn_Ribbon PF08271.7 XP_011275031.1 - 0.00066 18.9 0.7 0.00095 18.4 0.5 1.2 1 0 0 1 1 1 1 TFIIB zinc-binding IBR PF01485.16 XP_011275031.1 - 0.0011 18.8 0.4 0.0013 18.5 0.3 1.1 1 0 0 1 1 1 1 IBR domain zinc_ribbon_4 PF13717.1 XP_011275031.1 - 0.24 11.1 1.5 14 5.4 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 XP_011275031.1 - 0.27 10.8 1.5 16 5.2 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Metallophos PF00149.23 XP_011275032.1 - 1.9e-44 151.4 0.2 2.4e-44 151.1 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Vfa1 PF08432.5 XP_011275033.1 - 5e-44 150.5 15.2 5.9e-44 150.2 10.6 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 BBP1_C PF15272.1 XP_011275033.1 - 0.001 18.6 12.3 0.0016 18.0 8.5 1.3 1 0 0 1 1 1 1 Spindle pole body component BBP1, C-terminal Val_tRNA-synt_C PF10458.4 XP_011275033.1 - 0.0065 16.5 1.2 0.0065 16.5 0.8 3.0 3 0 0 3 3 3 1 Valyl tRNA synthetase tRNA binding arm CRT10 PF08728.5 XP_011275033.1 - 0.44 8.4 9.4 0.51 8.2 6.5 1.0 1 0 0 1 1 1 0 CRT10 Uds1 PF15456.1 XP_011275033.1 - 0.54 10.2 6.8 0.093 12.7 2.1 1.6 2 0 0 2 2 2 0 Up-regulated During Septation SLX9 PF15341.1 XP_011275033.1 - 2.4 8.5 13.5 0.84 10.0 6.5 2.0 1 1 1 2 2 2 0 Ribosome biogenesis protein SLX9 SRPRB PF09439.5 XP_011275034.1 - 4.4e-50 169.3 0.4 5.9e-50 168.9 0.3 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 XP_011275034.1 - 2.3e-14 53.0 0.0 3.2e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 XP_011275034.1 - 6.5e-07 29.3 1.2 6.7e-07 29.2 0.1 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 XP_011275034.1 - 0.00013 21.4 0.1 0.0011 18.4 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 XP_011275034.1 - 0.02 14.2 0.2 0.02 14.2 0.1 1.8 2 1 0 2 2 2 0 Ferrous iron transport protein B AAA_14 PF13173.1 XP_011275034.1 - 0.039 13.8 0.1 0.063 13.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 XP_011275034.1 - 0.046 13.4 1.4 0.2 11.3 0.8 2.1 1 1 1 2 2 2 0 Archaeal ATPase TMEM154 PF15102.1 XP_011275035.1 - 0.00011 21.9 5.8 0.0004 20.0 4.0 2.1 1 0 0 1 1 1 1 TMEM154 protein family Kelch_3 PF13415.1 XP_011275035.1 - 0.00012 22.1 2.1 0.24 11.5 0.0 3.2 3 0 0 3 3 3 2 Galactose oxidase, central domain Chordopox_A13L PF05961.6 XP_011275035.1 - 0.0038 17.1 0.3 0.022 14.6 0.2 2.4 1 0 0 1 1 1 1 Chordopoxvirus A13L protein Kelch_6 PF13964.1 XP_011275035.1 - 0.0058 16.7 1.1 2.6 8.3 0.0 3.4 3 0 0 3 3 3 1 Kelch motif SKG6 PF08693.5 XP_011275035.1 - 0.014 14.7 1.3 0.031 13.5 0.9 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Kelch_1 PF01344.20 XP_011275035.1 - 0.015 14.7 3.1 0.14 11.7 0.0 3.4 3 0 0 3 3 3 0 Kelch motif DUF872 PF05915.7 XP_011275035.1 - 0.17 11.7 3.5 0.11 12.3 0.2 2.5 2 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) RIC3 PF15361.1 XP_011275035.1 - 0.2 11.8 6.2 0.33 11.1 2.9 2.3 1 1 1 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 DUF912 PF06024.7 XP_011275035.1 - 1.1 9.3 5.6 1.7 8.7 2.0 3.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Podoplanin PF05808.6 XP_011275035.1 - 3.3 7.2 8.6 0.62 9.6 2.7 2.1 2 0 0 2 2 2 0 Podoplanin Pkinase PF00069.20 XP_011275036.1 - 2.3e-57 194.0 0.0 4.5e-57 193.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011275036.1 - 2.8e-30 105.2 0.0 5e-30 104.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 XP_011275036.1 - 5.8e-07 28.7 0.0 1.2e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like DUF4110 PF13422.1 XP_011275036.1 - 0.0084 15.9 0.1 0.02 14.7 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4110) POPLD PF08170.7 XP_011275036.1 - 0.14 12.0 0.3 1.5 8.6 0.0 2.6 2 0 0 2 2 2 0 POPLD (NUC188) domain Glyco_transf_15 PF01793.11 XP_011275037.1 - 1e-74 251.4 14.5 1e-74 251.4 10.0 2.1 2 0 0 2 2 2 1 Glycolipid 2-alpha-mannosyltransferase DUF2360 PF10152.4 XP_011275037.1 - 0.0097 16.1 0.1 0.12 12.6 0.0 2.2 2 0 0 2 2 2 1 Predicted coiled-coil domain-containing protein (DUF2360) Alk_phosphatase PF00245.15 XP_011275038.1 - 3.1e-118 395.1 0.0 3.8e-118 394.8 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 XP_011275038.1 - 1.9e-05 24.1 0.0 5.7e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 Metalloenzyme superfamily COX16 PF14138.1 XP_011275039.1 - 1.2e-26 92.6 0.2 1.9e-26 92.0 0.1 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 Ribophorin_I PF04597.9 XP_011275040.1 - 6.1e-127 423.7 9.2 6.9e-127 423.5 6.4 1.0 1 0 0 1 1 1 1 Ribophorin I eIF-3_zeta PF05091.7 XP_011275041.1 - 9.2e-154 512.8 3.5 1e-153 512.6 2.5 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Proteasome PF00227.21 XP_011275042.1 - 2.9e-41 140.8 0.4 7.2e-39 133.0 0.3 2.0 1 1 0 1 1 1 1 Proteasome subunit adh_short PF00106.20 XP_011275043.1 - 2.7e-32 111.9 0.1 3.4e-32 111.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 XP_011275043.1 - 3.7e-28 98.9 0.7 4.4e-28 98.6 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 XP_011275043.1 - 3.3e-14 52.9 0.1 4.6e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 XP_011275043.1 - 1.4e-06 27.9 0.7 4.3e-06 26.3 0.5 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 XP_011275043.1 - 2.7e-05 23.0 0.3 3.6e-05 22.6 0.2 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Eno-Rase_NADH_b PF12242.3 XP_011275043.1 - 0.003 17.3 0.1 0.0078 15.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3HCDH_N PF02737.13 XP_011275043.1 - 0.021 14.5 0.3 0.038 13.6 0.2 1.5 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1776 PF08643.5 XP_011275043.1 - 0.062 12.4 0.2 0.5 9.4 0.1 2.0 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) THF_DHG_CYH_C PF02882.14 XP_011275043.1 - 0.09 11.8 1.5 0.11 11.5 0.2 2.0 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain KAT11 PF08214.6 XP_011275044.1 - 2.3e-90 303.1 3.8 3e-90 302.8 2.6 1.1 1 0 0 1 1 1 1 Histone acetylation protein Dynamin_M PF01031.15 XP_011275045.1 - 6.2e-113 376.4 0.0 1e-112 375.7 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 XP_011275045.1 - 3.8e-53 179.7 0.0 3.8e-53 179.7 0.0 2.5 2 1 0 2 2 2 1 Dynamin family GED PF02212.13 XP_011275045.1 - 1.1e-29 102.1 2.0 2.9e-29 100.7 1.4 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 XP_011275045.1 - 0.00043 20.2 0.3 0.0076 16.2 0.2 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 XP_011275045.1 - 0.03 14.8 0.0 0.12 12.8 0.0 2.0 1 0 0 1 1 1 0 Miro-like protein zf-CCHC_4 PF14392.1 XP_011275045.1 - 0.058 13.0 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Zinc knuckle Neur_chan_memb PF02932.11 XP_011275045.1 - 0.066 13.0 1.5 0.18 11.6 1.1 1.7 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Apolipoprotein PF01442.13 XP_011275046.1 - 0.00024 20.6 3.7 0.00035 20.1 2.6 1.3 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Phasin PF05597.6 XP_011275046.1 - 0.0023 17.6 3.4 0.0035 17.1 2.4 1.2 1 0 0 1 1 1 1 Poly(hydroxyalcanoate) granule associated protein (phasin) ApoLp-III PF07464.6 XP_011275046.1 - 0.017 15.1 3.2 0.023 14.7 2.2 1.2 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Prominin PF05478.6 XP_011275046.1 - 0.019 12.5 1.6 0.027 12.0 1.1 1.2 1 0 0 1 1 1 0 Prominin AAA_13 PF13166.1 XP_011275046.1 - 0.032 12.7 4.4 0.036 12.5 3.1 1.1 1 0 0 1 1 1 0 AAA domain DUF4071 PF13281.1 XP_011275046.1 - 0.035 12.9 0.9 0.036 12.8 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) Corona_S2 PF01601.11 XP_011275046.1 - 0.049 11.7 1.5 0.061 11.4 1.0 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein DUF4142 PF13628.1 XP_011275046.1 - 0.057 13.4 1.5 0.094 12.7 1.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4142) DUF2636 PF11120.3 XP_011275046.1 - 0.064 12.7 1.0 0.13 11.7 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2636) Baculo_PEP_C PF04513.7 XP_011275046.1 - 0.092 12.5 4.8 0.32 10.8 2.6 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus COQ7 PF03232.8 XP_011275046.1 - 0.11 11.9 2.0 0.15 11.4 0.7 1.7 1 1 0 2 2 2 0 Ubiquinone biosynthesis protein COQ7 DUF4618 PF15397.1 XP_011275046.1 - 0.14 11.4 6.9 0.36 10.1 4.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) Mer2 PF09074.5 XP_011275046.1 - 0.16 11.8 7.0 0.23 11.3 4.8 1.2 1 0 0 1 1 1 0 Mer2 Mitofilin PF09731.4 XP_011275046.1 - 0.19 10.3 6.6 0.23 10.0 4.5 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein 7TMR-HDED PF07697.6 XP_011275046.1 - 0.22 11.2 4.8 0.2 11.3 2.7 1.4 1 1 0 1 1 1 0 7TM-HD extracellular DUF87 PF01935.12 XP_011275046.1 - 0.26 11.0 2.8 0.32 10.7 2.0 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF87 DUF1451 PF07295.6 XP_011275046.1 - 0.51 10.1 3.2 0.77 9.5 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) DUF4404 PF14357.1 XP_011275046.1 - 1.1 9.7 9.6 4.5 7.7 1.0 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF4404) Dict-STAT-coil PF09267.5 XP_011275046.1 - 4.6 7.4 10.5 1.6 9.0 4.8 1.9 1 1 1 2 2 2 0 Dictyostelium STAT, coiled coil Laminin_II PF06009.7 XP_011275046.1 - 7.2 6.3 8.7 2.5e+02 1.3 6.0 2.2 1 1 0 1 1 1 0 Laminin Domain II FliT PF05400.8 XP_011275046.1 - 8.6 6.8 10.2 1 9.8 3.8 1.8 2 0 0 2 2 2 0 Flagellar protein FliT DUF2063 PF09836.4 XP_011275047.1 - 0.0025 17.7 0.2 0.33 10.9 0.0 2.6 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2063) DUF1311 PF07007.7 XP_011275047.1 - 0.027 14.5 2.1 4 7.6 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1311) DUF684 PF05075.9 XP_011275047.1 - 0.03 12.9 7.8 0.46 9.0 0.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF684) DUF2894 PF11445.3 XP_011275047.1 - 0.054 13.7 1.3 0.071 13.3 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) Phage_GPO PF05929.6 XP_011275047.1 - 0.058 12.6 4.4 0.087 12.0 3.0 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Exonuc_VII_L PF02601.10 XP_011275047.1 - 0.13 11.4 5.3 0.17 11.0 3.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Laminin_II PF06009.7 XP_011275047.1 - 0.18 11.5 7.9 0.17 11.6 0.5 2.6 1 1 1 2 2 2 0 Laminin Domain II Bacillus_HBL PF05791.6 XP_011275047.1 - 0.47 9.7 12.6 0.88 8.9 8.7 1.3 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) T_Ag_DNA_bind PF02217.11 XP_011275047.1 - 0.6 10.5 2.9 6.7 7.1 0.2 2.8 1 1 2 3 3 3 0 Origin of replication binding protein AAA_32 PF13654.1 XP_011275047.1 - 0.62 8.6 7.6 0.84 8.2 5.3 1.1 1 0 0 1 1 1 0 AAA domain DUF342 PF03961.8 XP_011275047.1 - 0.66 8.3 5.2 0.87 7.9 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) TipAS PF07739.8 XP_011275047.1 - 2 8.7 5.3 5.7 7.2 0.5 2.4 1 1 1 2 2 2 0 TipAS antibiotic-recognition domain OmpH PF03938.9 XP_011275047.1 - 8.2 6.3 10.6 30 4.5 7.3 1.8 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) WD40 PF00400.27 XP_011275049.1 - 5.6e-38 127.4 0.7 4e-08 32.8 0.0 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat Sof1 PF04158.9 XP_011275049.1 - 3.3e-32 110.3 13.4 5.5e-32 109.6 9.3 1.4 1 0 0 1 1 1 1 Sof1-like domain BBS2_Mid PF14783.1 XP_011275049.1 - 0.0012 18.5 0.1 0.061 13.1 0.0 3.1 3 1 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region NIF PF03031.13 XP_011275050.1 - 1.9e-49 167.3 0.1 4.2e-49 166.2 0.1 1.6 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase SprA-related PF12118.3 XP_011275050.1 - 7.6 5.7 27.9 11 5.2 19.4 1.1 1 0 0 1 1 1 0 SprA-related family LMBR1 PF04791.11 XP_011275050.1 - 8.1 4.8 8.9 11 4.4 6.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Macoilin PF09726.4 XP_011275050.1 - 8.2 4.5 28.0 11 4.1 19.4 1.1 1 0 0 1 1 1 0 Transmembrane protein NPCC PF08058.6 XP_011275051.1 - 3e-23 82.2 7.2 1.3e-22 80.1 5.0 2.0 1 1 0 1 1 1 1 Nuclear pore complex component FliD_N PF02465.13 XP_011275051.1 - 0.33 11.3 10.0 0.22 11.8 5.4 1.8 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus ETRAMP PF09716.5 XP_011275051.1 - 1.9 8.4 6.7 1.1 9.2 0.1 2.7 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) PNP_UDP_1 PF01048.15 XP_011275052.1 - 7.8e-35 119.9 0.0 9.2e-35 119.7 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily DUF4193 PF13834.1 XP_011275052.1 - 0.081 13.0 0.1 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4193) Cauli_DNA-bind PF03310.8 XP_011275052.1 - 0.087 12.6 0.1 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Caulimovirus DNA-binding protein Aldo_ket_red PF00248.16 XP_011275053.1 - 3.2e-56 190.2 0.0 4.2e-56 189.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family GST_N_3 PF13417.1 XP_011275053.1 - 3.2e-07 30.4 0.0 6.9e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 XP_011275053.1 - 3.4e-07 30.3 0.0 8.2e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 XP_011275053.1 - 1.1e-06 28.5 0.0 2.4e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 XP_011275053.1 - 2.7e-05 24.0 0.0 6.4e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 XP_011275053.1 - 0.001 19.5 0.0 0.0026 18.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 XP_011275054.1 - 5.3e-08 32.9 0.1 1.8e-07 31.2 0.1 1.9 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 XP_011275054.1 - 7.2e-07 29.1 0.1 2.9e-06 27.1 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 XP_011275054.1 - 1e-05 25.6 0.0 2.7e-05 24.2 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 XP_011275054.1 - 4e-05 23.5 0.0 6.4e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ArsC PF03960.10 XP_011275054.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 ArsC family GST_C PF00043.20 XP_011275055.1 - 5.7e-09 35.8 0.0 1e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 XP_011275055.1 - 1.3e-05 25.3 0.0 2.6e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 XP_011275055.1 - 0.00027 21.1 0.0 0.00058 20.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 XP_011275055.1 - 0.00042 20.7 0.0 0.00088 19.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 XP_011275055.1 - 0.014 15.2 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 XP_011275055.1 - 0.038 13.9 0.0 0.074 13.0 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain CN_hydrolase PF00795.17 XP_011275056.1 - 7.1e-32 110.2 0.0 1.9e-31 108.8 0.0 1.6 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase Ras PF00071.17 XP_011275057.1 - 1.6e-44 151.1 0.2 2.5e-44 150.5 0.1 1.3 1 0 0 1 1 1 1 Ras family Arf PF00025.16 XP_011275057.1 - 1e-18 67.1 0.1 1.5e-18 66.6 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 XP_011275057.1 - 2.8e-16 60.0 0.0 5.3e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 XP_011275057.1 - 1.8e-08 34.0 0.2 1.9e-07 30.6 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 XP_011275057.1 - 6.2e-06 25.5 0.5 8.8e-06 25.0 0.3 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 XP_011275057.1 - 0.00037 19.7 0.4 0.00059 19.1 0.1 1.6 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 XP_011275057.1 - 0.0004 20.3 0.0 0.00088 19.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 XP_011275057.1 - 0.00067 19.1 0.4 0.14 11.6 0.0 2.4 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 XP_011275057.1 - 0.016 15.3 0.1 0.034 14.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 XP_011275057.1 - 0.031 14.1 0.1 0.066 13.1 0.1 1.7 1 1 0 1 1 1 0 AAA domain ArgK PF03308.11 XP_011275057.1 - 0.043 12.5 0.0 1.4 7.6 0.0 2.1 2 0 0 2 2 2 0 ArgK protein FtsK_SpoIIIE PF01580.13 XP_011275057.1 - 0.068 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF258 PF03193.11 XP_011275057.1 - 0.07 12.3 0.1 0.22 10.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF258 IDEAL PF08858.5 XP_011275057.1 - 0.1 12.1 0.1 0.88 9.1 0.0 2.4 2 0 0 2 2 2 0 IDEAL domain Hpr_kinase_C PF07475.7 XP_011275057.1 - 0.12 11.6 1.0 5.1 6.3 0.1 2.5 2 1 0 2 2 2 0 HPr Serine kinase C-terminal domain ABC_tran PF00005.22 XP_011275057.1 - 0.45 10.8 2.9 0.88 9.8 2.0 2.0 1 1 0 1 1 1 0 ABC transporter SYS1 PF09801.4 XP_011275058.1 - 1.3e-49 167.9 14.6 1.5e-49 167.7 10.1 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network DEAD PF00270.24 XP_011275059.1 - 1.8e-43 147.9 0.4 5e-43 146.5 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 XP_011275059.1 - 3.6e-24 84.4 0.0 1.1e-23 82.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 XP_011275059.1 - 0.046 13.8 0.4 0.18 11.9 0.3 2.1 1 1 0 1 1 1 0 AAA domain ELMO_CED12 PF04727.8 XP_011275060.1 - 0.00077 19.0 3.4 0.00077 19.0 2.3 2.1 1 1 1 2 2 2 1 ELMO/CED-12 family Zn_clus PF00172.13 XP_011275061.1 - 0.0011 18.8 1.9 0.0011 18.8 1.3 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain BNR PF02012.15 XP_011275062.1 - 5.4e-07 28.4 44.3 1.6 8.8 0.2 11.7 12 0 0 12 12 12 8 BNR/Asp-box repeat Cgr1 PF03879.9 XP_011275063.1 - 2.4e-36 124.1 33.3 2.9e-36 123.9 23.1 1.0 1 0 0 1 1 1 1 Cgr1 family CytochromB561_N PF09786.4 XP_011275063.1 - 0.19 10.1 4.0 0.2 10.0 2.7 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal PRP1_N PF06424.7 XP_011275063.1 - 0.22 11.8 13.7 0.26 11.6 9.5 1.2 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal G0-G1_switch_2 PF15103.1 XP_011275063.1 - 0.73 10.0 6.6 1.2 9.3 4.6 1.4 1 0 0 1 1 1 0 G0/G1 switch protein 2 APG6 PF04111.7 XP_011275063.1 - 2.1 7.2 14.3 2.3 7.1 9.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 XP_011275063.1 - 2.4 7.7 11.5 2.6 7.5 8.0 1.2 1 0 0 1 1 1 0 IncA protein AIF_C PF14721.1 XP_011275063.1 - 3 8.0 7.9 4.2 7.6 5.5 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF702 PF05142.7 XP_011275063.1 - 3.5 7.7 11.5 5.8 7.0 7.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF702) DUF4140 PF13600.1 XP_011275063.1 - 3.6 8.0 13.3 0.14 12.5 2.8 2.2 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF4407 PF14362.1 XP_011275063.1 - 4.2 6.2 9.9 4.5 6.1 6.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HI0933_like PF03486.9 XP_011275063.1 - 4.4 5.6 8.2 5.2 5.4 5.7 1.0 1 0 0 1 1 1 0 HI0933-like protein Vfa1 PF08432.5 XP_011275063.1 - 8.6 6.3 22.1 9.8 6.1 15.3 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF87 PF01935.12 XP_011275063.1 - 9.1 6.0 9.5 11 5.7 6.6 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF87 Trypan_PARP PF05887.6 XP_011275064.1 - 0.00029 20.6 13.9 0.00051 19.8 9.6 1.4 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) DUF1279 PF06916.8 XP_011275066.1 - 6.1e-27 93.7 0.0 1.3e-26 92.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Uricase PF01014.13 XP_011275067.1 - 1.4e-73 245.4 1.8 1.4e-39 135.3 1.2 2.1 2 0 0 2 2 2 2 Uricase FolB PF02152.13 XP_011275067.1 - 0.052 13.7 0.2 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 Dihydroneopterin aldolase DUF3533 PF12051.3 XP_011275068.1 - 1.4e-102 343.3 18.1 1.9e-102 342.8 12.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) PDR_CDR PF06422.7 XP_011275068.1 - 0.91 9.2 0.0 0.91 9.2 0.0 3.4 5 0 0 5 5 5 0 CDR ABC transporter DUF3533 PF12051.3 XP_011275069.1 - 3e-105 352.1 20.4 4.4e-105 351.5 14.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) DUF588 PF04535.7 XP_011275069.1 - 0.049 13.2 1.7 0.099 12.2 1.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF588) DUF912 PF06024.7 XP_011275069.1 - 0.061 13.3 0.1 0.31 11.1 0.0 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Ribosomal_L24e PF01246.15 XP_011275070.1 - 1.4e-34 117.7 0.4 1.4e-34 117.7 0.3 2.1 2 1 0 2 2 2 1 Ribosomal protein L24e DUF775 PF05603.7 XP_011275070.1 - 0.16 11.4 1.8 0.21 11.1 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF775) DUF724 PF05266.9 XP_011275070.1 - 2 7.9 8.1 3 7.4 5.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Ribosomal_L7Ae PF01248.21 XP_011275071.1 - 7.9e-25 86.2 0.0 8.7e-25 86.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SSF PF00474.12 XP_011275072.1 - 1.4e-06 27.2 30.0 2.8e-05 22.9 20.8 2.2 1 1 0 1 1 1 1 Sodium:solute symporter family Cyto_heme_lyase PF01265.12 XP_011275073.1 - 2.9e-76 256.4 0.0 3.3e-76 256.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase PPR_2 PF13041.1 XP_011275074.1 - 2.3e-24 85.1 8.8 1.5e-10 40.8 0.5 5.6 4 2 1 5 5 5 4 PPR repeat family PPR_3 PF13812.1 XP_011275074.1 - 3.8e-12 45.4 0.1 0.0018 18.4 0.0 6.7 6 0 0 6 6 6 2 Pentatricopeptide repeat domain PPR PF01535.15 XP_011275074.1 - 8.4e-12 44.2 5.7 0.00048 19.9 0.0 7.5 8 0 0 8 8 8 3 PPR repeat PPR_1 PF12854.2 XP_011275074.1 - 7.1e-10 38.1 2.2 0.0089 15.4 0.0 4.9 5 0 0 5 5 5 3 PPR repeat SPOB_a PF14689.1 XP_011275074.1 - 0.0023 17.4 2.8 1.4 8.5 0.1 4.4 4 0 0 4 4 4 2 Sensor_kinase_SpoOB-type, alpha-helical domain LOH1CR12 PF10158.4 XP_011275074.1 - 0.13 12.0 4.7 0.5 10.1 0.0 3.2 2 1 1 3 3 3 0 Tumour suppressor protein DKNYY PF13644.1 XP_011275075.1 - 0.0097 16.1 3.0 0.0097 16.1 2.1 2.3 2 1 1 3 3 3 1 DKNYY family zf-RING_5 PF14634.1 XP_011275075.1 - 0.54 10.0 4.9 1.2 8.9 3.4 1.5 1 0 0 1 1 1 0 zinc-RING finger domain MULE PF10551.4 XP_011275076.1 - 1.9e-06 27.9 0.1 1.6e-05 24.9 0.0 2.5 2 0 0 2 2 2 1 MULE transposase domain PEPCK_ATP PF01293.15 XP_011275077.1 - 5.1e-220 730.8 0.0 6.2e-220 730.5 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.1 XP_011275077.1 - 0.019 14.8 0.1 0.2 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 XP_011275077.1 - 0.051 13.1 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MRFAP1 PF15155.1 XP_011275077.1 - 0.064 13.5 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 MORF4 family-associated protein1 KaiC PF06745.8 XP_011275077.1 - 0.11 11.6 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_13 PF13166.1 XP_011275077.1 - 0.23 9.8 0.0 0.35 9.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain PTPA PF03095.10 XP_011275078.1 - 5.4e-102 340.9 0.0 7.9e-102 340.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Biotin_lipoyl_2 PF13533.1 XP_011275079.1 - 0.061 12.9 0.0 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 Biotin-lipoyl like TBX PF12598.3 XP_011275079.1 - 0.81 10.1 10.5 1.1 9.7 0.2 2.7 2 0 0 2 2 2 0 T-box transcription factor DAO PF01266.19 XP_011275080.1 - 7.1e-54 183.0 0.0 9.9e-54 182.5 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 XP_011275080.1 - 1.5e-11 43.7 2.2 7.3e-11 41.5 1.5 1.9 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 XP_011275080.1 - 1.8e-10 40.5 0.4 5.2e-08 32.4 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 XP_011275080.1 - 9.1e-07 28.2 0.0 0.034 13.2 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 XP_011275080.1 - 1.6e-06 28.1 0.4 0.00063 19.6 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 XP_011275080.1 - 4.7e-05 22.4 0.9 0.0051 15.7 0.1 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.12 XP_011275080.1 - 0.00025 20.2 0.0 0.046 12.8 0.0 2.4 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 XP_011275080.1 - 0.00099 17.6 0.3 0.0024 16.4 0.2 1.6 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_10 PF13460.1 XP_011275080.1 - 0.0029 17.6 0.8 0.37 10.7 0.1 3.3 4 0 0 4 4 4 1 NADH(P)-binding NAD_binding_8 PF13450.1 XP_011275080.1 - 0.0043 17.0 0.3 0.011 15.7 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.13 XP_011275080.1 - 0.0099 15.5 1.6 0.043 13.4 1.1 2.0 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 XP_011275080.1 - 0.044 14.1 0.1 0.11 12.9 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 XP_011275080.1 - 0.067 13.2 0.1 0.26 11.2 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 XP_011275080.1 - 0.093 11.6 0.1 0.58 9.0 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein ACT_4 PF13291.1 XP_011275081.1 - 1 9.7 6.4 1.1 9.6 0.3 2.7 2 1 1 3 3 3 0 ACT domain Adaptin_binding PF10199.4 XP_011275081.1 - 9.5 6.5 12.6 21 5.3 8.7 1.8 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Thiolase_N PF00108.18 XP_011275082.1 - 1e-82 277.0 0.5 3e-82 275.5 0.3 1.7 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 XP_011275082.1 - 1.7e-45 153.4 0.6 3.3e-45 152.4 0.4 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 XP_011275082.1 - 0.0093 15.6 3.3 0.097 12.3 0.0 3.4 4 0 0 4 4 4 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III zf-HIT PF04438.11 XP_011275083.1 - 6.2e-05 22.5 10.0 0.00011 21.8 7.0 1.4 1 0 0 1 1 1 1 HIT zinc finger Pyr_redox_3 PF13738.1 XP_011275084.1 - 9.7e-07 29.0 0.0 0.0016 18.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 XP_011275084.1 - 3.4e-06 27.0 0.0 3.7e-05 23.6 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 XP_011275084.1 - 7.1e-05 22.7 0.0 0.00014 21.7 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 XP_011275084.1 - 0.00017 21.4 0.0 0.00033 20.4 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 XP_011275084.1 - 0.00073 19.8 0.0 0.39 11.1 0.1 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 XP_011275084.1 - 0.0039 15.7 0.0 0.0066 14.9 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_7 PF13241.1 XP_011275084.1 - 0.0044 17.2 0.0 2.2 8.5 0.0 2.5 2 1 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_2 PF00890.19 XP_011275084.1 - 0.015 14.1 0.0 1.3 7.8 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.12 XP_011275084.1 - 0.027 13.5 0.0 0.088 11.8 0.0 1.8 2 0 0 2 2 2 0 Thi4 family Pex14_N PF04695.8 XP_011275084.1 - 0.028 14.4 0.6 0.053 13.5 0.4 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FAD_binding_3 PF01494.14 XP_011275084.1 - 0.1 11.6 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.19 XP_011275084.1 - 0.11 11.3 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 XP_011275084.1 - 0.16 10.8 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein F1F0-ATPsyn_F PF10791.4 XP_011275085.1 - 1.8e-40 137.0 0.2 2e-40 136.8 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.4 XP_011275085.1 - 0.033 14.2 0.0 0.053 13.5 0.0 1.3 1 1 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f LSM PF01423.17 XP_011275086.1 - 7.2e-15 54.2 0.2 9.9e-15 53.8 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 XP_011275086.1 - 0.0014 18.4 0.1 0.0019 18.0 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain RhoGAP PF00620.22 XP_011275087.1 - 6.2e-40 136.2 1.5 1.1e-39 135.4 0.4 2.0 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.17 XP_011275087.1 - 5.6e-14 51.9 23.0 1.6e-08 34.5 2.2 2.5 2 0 0 2 2 2 2 LIM domain OmpH PF03938.9 XP_011275087.1 - 0.0071 16.2 8.7 0.0071 16.2 6.0 2.0 3 0 0 3 3 3 1 Outer membrane protein (OmpH-like) TMF_TATA_bd PF12325.3 XP_011275087.1 - 0.012 15.3 10.3 0.046 13.4 7.2 2.1 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Myosin_tail_1 PF01576.14 XP_011275087.1 - 0.018 12.8 16.2 0.028 12.1 11.2 1.2 1 0 0 1 1 1 0 Myosin tail APG6 PF04111.7 XP_011275087.1 - 0.51 9.3 21.0 0.17 10.9 12.2 2.0 2 0 0 2 2 2 0 Autophagy protein Apg6 SseC PF04888.7 XP_011275087.1 - 1.2 8.4 8.7 2 7.6 6.0 1.3 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family IncA PF04156.9 XP_011275087.1 - 2.3 7.7 18.7 7.4 6.1 13.0 1.8 1 0 0 1 1 1 0 IncA protein DUF3450 PF11932.3 XP_011275087.1 - 6.4 5.9 19.9 0.95 8.6 10.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Glyco_tranf_2_3 PF13641.1 XP_011275088.1 - 4.5e-13 49.5 0.0 8.5e-13 48.6 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 XP_011275088.1 - 2.5e-12 46.4 0.0 4.1e-08 32.7 0.0 3.1 3 0 0 3 3 3 2 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 XP_011275088.1 - 1.9e-05 24.3 0.4 6.1e-05 22.7 0.3 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 2 Tn7_Tnp_TnsA_C PF08721.6 XP_011275089.1 - 0.00081 19.3 5.6 0.15 12.1 0.1 4.2 4 0 0 4 4 4 2 TnsA endonuclease C terminal ClpS PF02617.12 XP_011275089.1 - 0.013 15.1 0.1 0.37 10.5 0.0 2.9 3 0 0 3 3 3 0 ATP-dependent Clp protease adaptor protein ClpS DUF4342 PF14242.1 XP_011275089.1 - 0.89 9.3 3.1 17 5.3 0.3 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4342) Rhodanese PF00581.15 XP_011275090.1 - 1.2e-13 51.4 0.0 1.5e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain TPP_enzyme_N PF02776.13 XP_011275091.1 - 2.9e-30 105.0 0.0 5e-30 104.2 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 XP_011275091.1 - 1.5e-16 60.4 0.0 3.3e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 XP_011275091.1 - 3.1e-14 52.8 0.0 5.7e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Afi1 PF07792.7 XP_011275092.1 - 6.1e-23 81.4 0.0 1.2e-22 80.5 0.0 1.5 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 XP_011275092.1 - 4.7e-16 58.5 2.9 1.2e-15 57.1 2.0 1.8 1 0 0 1 1 1 1 Stabilization of polarity axis RRM_1 PF00076.17 XP_011275093.1 - 1.6e-12 46.8 0.2 4.4e-12 45.4 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 XP_011275093.1 - 5.5e-09 35.8 0.0 9e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 XP_011275093.1 - 4.8e-06 26.3 0.0 9.3e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 XP_011275093.1 - 0.0011 19.3 4.1 0.0011 19.3 2.8 2.8 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 DUF1122 PF06557.6 XP_011275093.1 - 0.009 15.1 1.1 0.016 14.3 0.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1122) Mito_carr PF00153.22 XP_011275095.1 - 5.7e-53 176.6 2.2 8.2e-17 60.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.22 XP_011275096.1 - 1.8e-64 213.4 2.2 1.9e-21 75.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein adh_short_C2 PF13561.1 XP_011275097.1 - 3.3e-30 105.6 0.3 3.8e-30 105.4 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 XP_011275097.1 - 8.2e-23 81.1 0.0 1e-22 80.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 XP_011275097.1 - 2.6e-08 33.7 0.0 3.6e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 KR domain CENP-N PF05238.8 XP_011275098.1 - 0.11 11.5 3.9 0.15 11.1 2.7 1.1 1 0 0 1 1 1 0 Kinetochore protein CHL4 like Daxx PF03344.10 XP_011275099.1 - 0.044 12.2 35.6 0.051 12.0 24.6 1.0 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 XP_011275099.1 - 0.55 9.4 47.2 0.63 9.2 32.7 1.1 1 0 0 1 1 1 0 SDA1 DUF2265 PF10023.4 XP_011275099.1 - 6.4 5.8 14.0 9.6 5.2 9.7 1.2 1 0 0 1 1 1 0 Predicted aminopeptidase (DUF2265) NDUF_B7 PF05676.8 XP_011275100.1 - 3.6e-25 87.1 2.7 4.4e-25 86.8 1.9 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.5 XP_011275100.1 - 0.0015 18.2 2.1 0.0021 17.7 1.4 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 XP_011275100.1 - 0.24 11.4 2.2 0.29 11.1 1.1 1.4 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 GATA PF00320.22 XP_011275101.1 - 5.1e-14 51.3 2.9 9.2e-14 50.5 2.0 1.4 1 0 0 1 1 1 1 GATA zinc finger Nudix_N_2 PF14803.1 XP_011275101.1 - 0.12 12.0 0.8 0.26 10.9 0.6 1.6 1 0 0 1 1 1 0 Nudix N-terminal TRAPP PF04051.11 XP_011275102.1 - 7.4e-27 93.7 0.0 8.4e-27 93.5 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Nro1 PF12753.2 XP_011275103.1 - 2.1e-140 468.2 30.3 2.4e-140 468.0 21.0 1.0 1 0 0 1 1 1 1 Nuclear pore complex subunit Nro1 TPR_12 PF13424.1 XP_011275103.1 - 0.021 14.7 3.3 2.3 8.2 0.4 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat TP_methylase PF00590.15 XP_011275104.1 - 5.7e-39 134.0 0.0 9.1e-39 133.3 0.0 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.1 XP_011275104.1 - 1.8e-06 28.1 0.0 4.4e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 XP_011275104.1 - 0.0042 16.3 0.1 0.56 9.5 0.0 2.7 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal Hydrolase_6 PF13344.1 XP_011275105.1 - 2.4e-26 91.5 0.0 4.8e-26 90.5 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 XP_011275105.1 - 9.1e-22 76.5 0.1 3.2e-21 74.8 0.0 2.0 3 0 0 3 3 3 1 HAD-hyrolase-like Hydrolase PF00702.21 XP_011275105.1 - 6.1e-06 26.7 0.0 0.00052 20.5 0.0 2.4 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 XP_011275105.1 - 0.00079 19.6 0.1 1.8 8.7 0.0 3.1 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase NAD_kinase PF01513.16 XP_011275105.1 - 0.043 12.5 0.0 0.067 11.9 0.0 1.2 1 0 0 1 1 1 0 ATP-NAD kinase Hydrolase_3 PF08282.7 XP_011275105.1 - 0.098 12.2 0.1 0.9 9.0 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase zf-AN1 PF01428.11 XP_011275106.1 - 1.3e-07 31.3 13.1 1.9e-07 30.8 9.1 1.2 1 0 0 1 1 1 1 AN1-like Zinc finger DDE_Tnp_4 PF13359.1 XP_011275106.1 - 0.041 13.4 0.9 0.062 12.9 0.6 1.4 1 1 0 1 1 1 0 DDE superfamily endonuclease MAGP PF05507.6 XP_011275106.1 - 0.091 12.5 5.1 0.12 12.1 3.5 1.2 1 0 0 1 1 1 0 Microfibril-associated glycoprotein (MAGP) DUF3835 PF12927.2 XP_011275106.1 - 0.68 10.9 0.3 0.68 10.9 0.2 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF3835) InvH PF04741.7 XP_011275106.1 - 0.7 9.7 10.0 1.1 9.1 6.7 1.3 1 1 0 1 1 1 0 InvH outer membrane lipoprotein DUF3795 PF12675.2 XP_011275106.1 - 1.6 8.9 10.8 0.83 9.8 4.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3795) PSCyt3 PF07627.6 XP_011275106.1 - 2 8.3 5.3 1.9 8.3 3.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1588) CIAPIN1 PF05093.8 XP_011275107.1 - 2.9e-31 107.4 4.0 5.7e-31 106.5 2.8 1.4 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Flavoprotein PF02441.14 XP_011275108.1 - 3.6e-43 146.3 0.0 8.1e-43 145.1 0.0 1.6 1 0 0 1 1 1 1 Flavoprotein RTBV_P46 PF06216.6 XP_011275108.1 - 0.091 11.5 0.8 0.16 10.7 0.5 1.3 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein Herpes_env PF01673.13 XP_011275108.1 - 0.13 10.8 3.5 0.076 11.5 0.1 2.0 2 0 0 2 2 2 0 Herpesvirus putative major envelope glycoprotein zf-C2H2 PF00096.21 XP_011275109.1 - 3.1e-10 39.7 4.7 3.1e-05 24.0 0.1 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 XP_011275109.1 - 8.4e-10 38.2 6.1 8.8e-05 22.5 1.6 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 XP_011275109.1 - 2.5e-07 30.6 11.5 2.5e-06 27.4 1.3 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.2 XP_011275109.1 - 0.0012 18.9 0.1 0.31 11.2 0.2 3.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type TrbC_Ftype PF09673.5 XP_011275109.1 - 0.013 15.1 0.2 0.048 13.2 0.1 2.0 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein zf-C2H2_jaz PF12171.3 XP_011275109.1 - 0.31 11.2 0.1 0.31 11.2 0.1 4.3 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 XP_011275109.1 - 2.9 7.7 6.7 0.93 9.3 0.2 2.8 2 1 1 3 3 3 0 BED zinc finger Cg6151-P PF10233.4 XP_011275110.1 - 1.6e-29 102.1 1.1 2.2e-29 101.7 0.8 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P Peptidase_M50B PF13398.1 XP_011275110.1 - 0.056 12.8 0.5 0.08 12.3 0.3 1.2 1 0 0 1 1 1 0 Peptidase M50B-like DUF2633 PF11119.3 XP_011275110.1 - 0.12 12.1 0.7 0.19 11.4 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) RVT_1 PF00078.22 XP_011275111.1 - 5.9e-07 29.0 0.1 8e-07 28.6 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2482 PF10655.4 XP_011275111.1 - 0.17 11.9 2.0 2 8.5 0.7 2.0 1 1 1 2 2 2 0 Hypothetical protein of unknown function (DUF2482) OPT PF03169.10 XP_011275112.1 - 4.2e-140 468.1 35.3 4.8e-140 467.9 24.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein HECT PF00632.20 XP_011275113.1 - 2.5e-92 309.4 0.0 3.7e-92 308.8 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 XP_011275113.1 - 7.3e-34 115.2 19.6 1.3e-11 44.1 1.4 3.7 3 0 0 3 3 3 3 WW domain C2 PF00168.25 XP_011275113.1 - 3.6e-17 61.9 0.2 9.6e-17 60.6 0.1 1.7 1 0 0 1 1 1 1 C2 domain Glyoxalase PF00903.20 XP_011275114.1 - 4.5e-17 62.2 0.2 1.8e-10 40.8 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 XP_011275114.1 - 4.4e-12 45.9 0.0 1.7e-05 24.7 0.0 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 XP_011275114.1 - 3.9e-07 30.6 0.0 0.0097 16.5 0.0 2.6 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_5 PF14696.1 XP_011275114.1 - 0.0011 18.9 0.2 0.0032 17.4 0.1 1.9 1 1 0 1 1 1 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.1 XP_011275114.1 - 0.0014 18.5 0.0 0.13 12.1 0.0 2.5 2 0 0 2 2 2 1 Glyoxalase-like domain Trypsin_2 PF13365.1 XP_011275115.1 - 2.7e-12 46.7 0.0 4.7e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.21 XP_011275115.1 - 4e-08 33.0 0.0 7e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Trypsin SNARE_assoc PF09335.6 XP_011275116.1 - 1.7e-11 44.3 9.7 1.7e-11 44.3 6.8 2.1 2 1 1 3 3 3 1 SNARE associated Golgi protein DUF2207 PF09972.4 XP_011275116.1 - 0.00092 17.9 17.1 0.026 13.1 0.0 3.0 2 1 1 3 3 3 3 Predicted membrane protein (DUF2207) E1-E2_ATPase PF00122.15 XP_011275116.1 - 0.024 13.6 0.2 0.095 11.7 0.0 1.9 2 0 0 2 2 2 0 E1-E2 ATPase PRCH PF03967.8 XP_011275116.1 - 0.082 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Photosynthetic reaction centre, H-chain N-terminal region DUF3336 PF11815.3 XP_011275117.1 - 2.7e-39 133.9 3.4 6.7e-39 132.7 2.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 XP_011275117.1 - 9.2e-30 104.0 0.0 2.2e-29 102.8 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase LIM PF00412.17 XP_011275118.1 - 5e-16 58.5 26.7 5.6e-09 35.9 5.9 2.5 2 0 0 2 2 2 2 LIM domain Pkinase PF00069.20 XP_011275119.1 - 3.5e-52 177.1 0.0 4.2e-52 176.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011275119.1 - 3.8e-15 55.6 0.0 6e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 XP_011275119.1 - 7.5e-08 32.3 0.0 2.3e-06 27.5 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 XP_011275119.1 - 0.016 14.8 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Seadorna_VP7 PF07387.6 XP_011275119.1 - 0.021 13.6 0.0 0.081 11.7 0.0 1.9 2 0 0 2 2 2 0 Seadornavirus VP7 Aconitase_B_N PF11791.3 XP_011275119.1 - 0.024 14.4 0.0 0.048 13.4 0.0 1.5 1 0 0 1 1 1 0 Aconitate B N-terminal domain DUF45 PF01863.12 XP_011275120.1 - 0.036 13.8 1.0 0.059 13.1 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF45 DUF1216 PF06746.6 XP_011275120.1 - 0.051 13.3 7.3 0.031 14.0 3.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1216) VPS11_C PF12451.3 XP_011275121.1 - 0.13 12.1 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Vacuolar protein sorting protein 11 C terminal IU_nuc_hydro PF01156.14 XP_011275123.1 - 1.4e-43 149.2 0.0 1.8e-43 148.9 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase DUF1593 PF07632.6 XP_011275123.1 - 0.028 13.7 0.0 0.046 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1593) FH2 PF02181.18 XP_011275124.1 - 9e-69 232.1 15.8 9e-69 232.1 10.9 2.7 2 1 0 3 3 3 1 Formin Homology 2 Domain Drf_GBD PF06371.8 XP_011275124.1 - 3.4e-20 72.1 0.3 3.4e-20 72.1 0.2 4.6 4 0 0 4 4 4 2 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 XP_011275124.1 - 5.1e-09 35.8 9.6 5.1e-09 35.8 6.7 3.9 5 1 0 5 5 5 1 Diaphanous FH3 Domain SKG6 PF08693.5 XP_011275125.1 - 1.6e-05 24.1 0.5 3.6e-05 22.9 0.3 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain SIT PF15330.1 XP_011275125.1 - 0.0075 16.3 3.2 0.011 15.8 0.1 2.4 2 1 1 3 3 3 1 SHP2-interacting transmembrane adaptor protein, SIT Coa1 PF08695.5 XP_011275126.1 - 3e-37 126.6 0.0 4.6e-37 126.0 0.0 1.3 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 DUF1748 PF08520.5 XP_011275127.1 - 1.7e-29 101.2 0.1 1.9e-29 101.0 0.1 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) Myb_DNA-bind_6 PF13921.1 XP_011275128.1 - 6e-30 103.1 10.3 1e-13 51.1 1.6 3.8 2 1 1 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 XP_011275128.1 - 3.4e-27 94.2 12.0 1.2e-09 38.1 0.0 4.1 3 1 0 3 3 3 3 Myb-like DNA-binding domain Rap1_C PF11626.3 XP_011275128.1 - 0.013 15.3 0.5 4 7.3 0.2 2.7 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Peptidase_M48 PF01435.13 XP_011275129.1 - 4.6e-32 111.4 0.0 6.6e-32 110.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_MA_2 PF13485.1 XP_011275129.1 - 0.046 13.7 0.0 0.67 10.0 0.0 2.3 2 0 0 2 2 2 0 Peptidase MA superfamily Kin17_mid PF10357.4 XP_011275130.1 - 1.3e-36 125.0 6.9 2.3e-36 124.2 4.8 1.4 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.3 XP_011275130.1 - 2.4e-06 27.4 4.0 2.4e-06 27.4 2.8 3.2 5 0 0 5 5 5 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 XP_011275130.1 - 0.00027 21.0 2.7 0.00027 21.0 1.9 2.7 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 XP_011275130.1 - 0.0065 16.5 0.7 0.0065 16.5 0.5 2.3 3 0 0 3 3 3 1 C2H2 type zinc-finger (2 copies) AKAP95 PF04988.7 XP_011275130.1 - 0.011 15.5 2.3 0.011 15.5 1.6 2.0 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) TFIID_90kDa PF04494.10 XP_011275130.1 - 0.039 14.0 0.9 0.039 14.0 0.6 2.1 2 0 0 2 2 2 0 WD40 associated region in TFIID subunit Peptidase_A3 PF02160.10 XP_011275130.1 - 0.48 9.9 5.2 0.16 11.5 1.6 1.6 2 0 0 2 2 2 0 Cauliflower mosaic virus peptidase (A3) TPR_11 PF13414.1 XP_011275131.1 - 1.3e-08 34.3 0.2 2e-05 24.1 0.4 2.8 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 XP_011275131.1 - 1.5e-07 30.7 0.8 0.00012 21.4 0.3 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 XP_011275131.1 - 6.4e-06 25.6 0.2 0.0072 16.1 0.4 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 XP_011275131.1 - 0.0018 18.1 0.1 0.57 10.1 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat MIT PF04212.13 XP_011275131.1 - 0.0025 17.6 1.0 0.01 15.6 0.1 2.4 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_7 PF13176.1 XP_011275131.1 - 0.011 15.4 0.1 0.044 13.5 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat F-box-like PF12937.2 XP_011275131.1 - 0.021 14.5 3.8 0.023 14.4 1.5 2.0 2 0 0 2 2 2 0 F-box-like LRR_8 PF13855.1 XP_011275131.1 - 0.31 10.8 15.9 2.7 7.8 0.2 5.8 5 1 1 6 6 6 0 Leucine rich repeat PGAP1 PF07819.8 XP_011275132.1 - 5.3e-90 300.9 0.0 9e-90 300.1 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 XP_011275132.1 - 0.00012 21.9 0.0 0.00027 20.7 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 XP_011275132.1 - 0.00025 21.0 0.0 0.0004 20.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 XP_011275132.1 - 0.0017 17.7 0.0 0.0034 16.6 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) LCAT PF02450.10 XP_011275132.1 - 0.0025 16.8 0.0 0.0044 16.0 0.0 1.3 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_1 PF00561.15 XP_011275132.1 - 0.0096 15.5 0.0 0.026 14.0 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2974 PF11187.3 XP_011275132.1 - 0.029 13.7 0.0 0.058 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Lipase_3 PF01764.20 XP_011275132.1 - 0.041 13.4 0.0 0.088 12.4 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) STE2 PF02116.10 XP_011275133.1 - 5.7e-89 297.9 20.7 6.8e-89 297.6 14.3 1.0 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR DUF2340 PF10209.4 XP_011275135.1 - 1e-39 135.4 0.1 1.2e-39 135.2 0.1 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) Rad60-SLD PF11976.3 XP_011275136.1 - 8e-12 44.6 7.6 5.5e-05 22.7 0.1 4.7 4 0 0 4 4 4 3 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 XP_011275136.1 - 0.015 14.6 2.1 3.3 7.1 0.0 3.2 3 0 0 3 3 3 0 Ubiquitin family Rad60-SLD PF11976.3 XP_011275137.1 - 4.5e-11 42.2 0.7 5.1e-11 42.0 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ribosomal_L3 PF00297.17 XP_011275139.1 - 2.4e-117 390.9 9.7 2.9e-117 390.7 6.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 Nucleoporin_C PF03177.9 XP_011275140.1 - 3.1e-60 204.3 29.3 4.8e-60 203.6 20.3 1.3 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 XP_011275140.1 - 1.1e-44 152.8 1.2 2.2e-44 151.9 0.8 1.4 1 0 0 1 1 1 1 Nup133 N terminal like DUF1340 PF07067.6 XP_011275140.1 - 0.0059 15.7 0.0 0.014 14.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1340) RTTN_N PF14726.1 XP_011275140.1 - 0.007 16.9 0.2 0.026 15.0 0.1 2.0 1 0 0 1 1 1 1 Rotatin, an armadillo repeat protein, centriole functioning Brix PF04427.13 XP_011275141.1 - 6e-35 120.6 0.9 7.8e-35 120.2 0.7 1.2 1 0 0 1 1 1 1 Brix domain THF_DHG_CYH_C PF02882.14 XP_011275142.1 - 5.8e-20 70.9 0.0 1.2e-11 44.0 0.0 2.8 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 XP_011275142.1 - 1.4e-18 67.0 0.0 2.7e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Shikimate_DH PF01488.15 XP_011275142.1 - 0.0066 16.5 0.1 0.14 12.2 0.0 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase AdoHcyase_NAD PF00670.16 XP_011275142.1 - 0.033 14.0 0.0 0.066 13.0 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Semialdhyde_dh PF01118.19 XP_011275142.1 - 0.071 13.4 0.1 0.17 12.1 0.0 1.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain RabGAP-TBC PF00566.13 XP_011275143.1 - 1.3e-53 181.6 1.9 2.1e-53 180.9 1.3 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Lactamase_B_2 PF12706.2 XP_011275144.1 - 4.8e-34 117.6 0.1 8.7e-34 116.7 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 XP_011275144.1 - 5.6e-20 70.5 0.0 1.2e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.22 XP_011275144.1 - 0.0087 15.7 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Vps5 PF09325.5 XP_011275145.1 - 4.4e-73 245.4 7.2 4.4e-73 245.4 5.0 1.9 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.19 XP_011275145.1 - 5.4e-24 84.1 0.1 2.4e-23 82.0 0.0 2.1 2 0 0 2 2 2 1 PX domain DUF1409 PF07197.7 XP_011275145.1 - 0.51 10.4 5.2 1.1 9.3 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1409) Alg6_Alg8 PF03155.10 XP_011275146.1 - 7.8e-141 470.1 40.2 9.4e-141 469.8 27.9 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family PHD PF00628.24 XP_011275147.1 - 2.5e-09 36.6 7.0 4.3e-09 35.9 4.9 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 XP_011275147.1 - 0.003 17.6 1.6 0.0078 16.3 1.1 1.7 1 0 0 1 1 1 1 PHD-like zinc-binding domain DUF4551 PF15087.1 XP_011275147.1 - 0.019 13.3 11.1 0.025 12.9 7.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) zf-C4_Topoisom PF01396.14 XP_011275147.1 - 0.83 9.2 9.2 0.064 12.7 1.0 2.3 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger Ndc1_Nup PF09531.5 XP_011275147.1 - 1.1 7.5 8.8 1.3 7.3 6.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Cytochrom_C1 PF02167.10 XP_011275148.1 - 2.5e-82 275.7 0.0 3.1e-82 275.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 XP_011275148.1 - 0.00072 19.6 0.0 0.0016 18.5 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 XP_011275148.1 - 0.0014 19.3 0.0 0.004 17.9 0.0 1.8 1 0 0 1 1 1 1 Cytochrome c FA_hydroxylase PF04116.8 XP_011275150.1 - 6.8e-16 58.6 19.7 6.8e-16 58.6 13.6 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily adh_short PF00106.20 XP_011275151.1 - 5.5e-30 104.4 0.0 6.8e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 XP_011275151.1 - 8.2e-13 48.6 0.0 1.1e-12 48.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 XP_011275151.1 - 2.7e-06 27.1 0.0 3.6e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 XP_011275151.1 - 0.0001 22.0 0.4 0.00019 21.1 0.3 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 XP_011275151.1 - 0.00026 20.2 0.0 0.00087 18.5 0.0 1.7 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) 2-Hacid_dh_C PF02826.14 XP_011275152.1 - 1.7e-45 154.3 0.0 3.1e-45 153.5 0.0 1.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 XP_011275152.1 - 4e-15 55.4 0.0 5.6e-15 54.9 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 XP_011275152.1 - 1.4e-05 24.9 0.0 5.6e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 XP_011275152.1 - 5.5e-05 23.2 0.1 0.00086 19.4 0.0 2.3 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase AdoHcyase_NAD PF00670.16 XP_011275152.1 - 0.0011 18.8 0.1 1.8 8.3 0.1 2.2 2 0 0 2 2 2 2 S-adenosyl-L-homocysteine hydrolase, NAD binding domain PBP_like PF12727.2 XP_011275152.1 - 0.1 11.5 0.0 0.18 10.7 0.0 1.4 1 0 0 1 1 1 0 PBP superfamily domain F420_oxidored PF03807.12 XP_011275152.1 - 0.11 12.9 0.0 0.55 10.6 0.0 2.2 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent STN PF07660.9 XP_011275153.1 - 0.11 12.1 0.9 4.8 6.8 0.1 3.0 2 0 0 2 2 2 0 Secretin and TonB N terminus short domain Arginase PF00491.16 XP_011275154.1 - 2.7e-84 282.7 0.0 3.4e-84 282.4 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 XP_011275154.1 - 0.029 14.5 0.0 0.066 13.4 0.0 1.6 1 0 0 1 1 1 0 UPF0489 domain Pyr_redox_2 PF07992.9 XP_011275155.1 - 8.4e-09 35.5 0.0 1.5e-08 34.7 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 XP_011275155.1 - 9.7e-07 29.1 1.3 3.7e-06 27.2 0.0 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 XP_011275155.1 - 0.013 14.4 0.0 0.019 13.9 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.7 XP_011275155.1 - 0.026 13.4 0.0 0.041 12.7 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.1 XP_011275155.1 - 0.06 13.4 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ATP13 PF12921.2 XP_011275156.1 - 0.0013 18.0 7.5 1.3 8.3 0.1 4.6 3 2 1 4 4 4 3 Mitochondrial ATPase expression PPR_3 PF13812.1 XP_011275156.1 - 0.033 14.4 0.5 65 4.1 0.0 5.1 7 0 0 7 7 7 0 Pentatricopeptide repeat domain PPR PF01535.15 XP_011275156.1 - 0.13 12.2 10.0 58 3.9 0.0 6.4 7 0 0 7 7 7 0 PPR repeat Apc3 PF12895.2 XP_011275156.1 - 0.19 11.8 2.6 11 6.2 0.0 4.5 4 1 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 Endosulfine PF04667.12 XP_011275157.1 - 6.5e-24 83.7 0.1 7.9e-24 83.4 0.1 1.1 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region INSIG PF07281.7 XP_011275158.1 - 6.7e-22 77.7 5.5 1.4e-21 76.7 3.8 1.5 1 1 0 1 1 1 1 Insulin-induced protein (INSIG) YrhC PF14143.1 XP_011275158.1 - 0.16 11.9 1.5 0.41 10.6 0.1 2.3 3 0 0 3 3 3 0 YrhC-like protein Far-17a_AIG1 PF04750.9 XP_011275159.1 - 1.3e-22 80.0 14.6 1.5e-22 79.7 10.1 1.1 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Herpes_LMP1 PF05297.6 XP_011275159.1 - 7.3 5.3 8.9 10 4.9 6.1 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF3112 PF11309.3 XP_011275161.1 - 1e-48 165.1 14.4 1.3e-48 164.8 4.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3112) AA_permease PF00324.16 XP_011275162.1 - 5.8e-130 433.8 41.6 7.2e-130 433.5 28.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 XP_011275162.1 - 9.8e-30 103.4 47.1 1.3e-29 102.9 32.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 XP_011275163.1 - 1e-125 419.8 44.9 1.2e-125 419.5 31.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 XP_011275163.1 - 1.3e-24 86.5 48.9 1.8e-24 86.0 33.9 1.1 1 0 0 1 1 1 1 Amino acid permease zf-C2H2 PF00096.21 XP_011275165.1 - 0.057 13.7 1.0 0.27 11.6 0.6 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type PaaSYMP PF14738.1 XP_011275165.1 - 0.09 12.4 1.6 2.4 7.8 0.0 2.3 2 0 0 2 2 2 0 Solute carrier (proton/amino acid symporter), TRAMD3 or PAT1 SUR7 PF06687.7 XP_011275166.1 - 9.4e-29 100.4 5.9 1.2e-28 100.1 4.1 1.1 1 0 0 1 1 1 1 SUR7/PalI family Tetraspannin PF00335.15 XP_011275166.1 - 0.011 15.0 0.1 0.02 14.1 0.1 1.5 1 0 0 1 1 1 0 Tetraspanin family RCR PF12273.3 XP_011275166.1 - 0.36 11.3 7.6 0.28 11.7 0.1 2.6 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Fig1 PF12351.3 XP_011275166.1 - 1.7 8.4 7.3 2.5 7.9 5.1 1.2 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 Sel1 PF08238.7 XP_011275167.1 - 1.7e-42 142.8 21.9 2.5e-08 34.3 0.1 8.7 10 0 0 10 10 10 7 Sel1 repeat DSPc PF00782.15 XP_011275168.1 - 3e-24 85.1 0.2 1.1e-23 83.2 0.1 1.9 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Yippee-Mis18 PF03226.9 XP_011275168.1 - 0.0014 18.6 1.7 0.005 16.8 0.3 2.5 2 1 0 2 2 2 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Y_phosphatase PF00102.22 XP_011275168.1 - 0.0022 17.3 0.0 0.015 14.6 0.0 2.0 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Trm112p PF03966.11 XP_011275168.1 - 0.026 14.8 0.4 0.2 12.0 0.2 2.3 1 1 1 2 2 2 0 Trm112p-like protein Occludin_ELL PF07303.8 XP_011275168.1 - 0.041 14.5 1.1 0.11 13.2 0.8 1.7 1 0 0 1 1 1 0 Occludin homology domain PTPlike_phytase PF14566.1 XP_011275168.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate HypA PF01155.14 XP_011275168.1 - 0.28 10.8 3.8 6.4 6.5 0.3 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Elf1 PF05129.8 XP_011275168.1 - 0.36 10.5 4.1 3.9 7.2 0.1 2.9 3 0 0 3 3 3 0 Transcription elongation factor Elf1 like zinc_ribbon_5 PF13719.1 XP_011275168.1 - 0.45 10.1 4.9 7.1 6.3 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 XP_011275168.1 - 1 9.0 6.0 8.1 6.2 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon domain Apc15p PF05841.6 XP_011275169.1 - 1.5e-06 28.9 0.5 1.5e-06 28.9 0.3 3.4 3 0 0 3 3 3 1 Apc15p protein DUF501 PF04417.7 XP_011275169.1 - 0.19 11.6 2.7 0.44 10.3 1.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF501) UbiA PF01040.13 XP_011275170.1 - 4.9e-23 81.6 17.0 6.5e-23 81.2 11.8 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family SpoIIIAH PF12685.2 XP_011275170.1 - 0.29 10.6 3.8 0.54 9.7 2.7 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein MitMem_reg PF13012.1 XP_011275171.1 - 6.4e-40 135.8 1.6 1.2e-39 134.9 0.5 1.9 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.16 XP_011275171.1 - 1.3e-27 95.7 0.0 2.7e-27 94.7 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF2999 PF11212.3 XP_011275171.1 - 0.021 14.8 0.5 0.54 10.3 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2999) Plasmid_parti PF01672.11 XP_011275171.1 - 0.18 12.2 3.7 0.54 10.7 0.1 2.8 2 0 0 2 2 2 0 Putative plasmid partition protein ATP_bind_1 PF03029.12 XP_011275172.1 - 4.6e-82 275.1 0.1 6e-82 274.7 0.1 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein ArgK PF03308.11 XP_011275172.1 - 6.4e-05 21.8 0.4 0.00023 20.0 0.0 1.8 2 0 0 2 2 2 1 ArgK protein AAA_17 PF13207.1 XP_011275172.1 - 8.4e-05 23.3 0.6 0.00038 21.2 0.0 2.3 2 1 0 3 3 2 1 AAA domain MMR_HSR1 PF01926.18 XP_011275172.1 - 0.0009 19.1 0.5 0.0062 16.4 0.0 2.5 2 2 1 3 3 3 1 50S ribosome-binding GTPase AAA_19 PF13245.1 XP_011275172.1 - 0.0077 15.9 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_29 PF13555.1 XP_011275172.1 - 0.0093 15.4 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_33 PF13671.1 XP_011275172.1 - 0.0093 15.8 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 XP_011275172.1 - 0.018 15.2 0.1 0.19 11.8 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA PF00004.24 XP_011275172.1 - 0.024 14.8 0.2 0.29 11.3 0.0 2.7 3 1 1 4 4 4 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 XP_011275172.1 - 0.031 13.7 0.0 0.04 13.3 0.0 1.3 1 1 0 1 1 1 0 AAA-like domain MobB PF03205.9 XP_011275172.1 - 0.056 13.1 0.0 0.2 11.3 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.18 XP_011275172.1 - 0.1 11.9 0.0 0.29 10.5 0.0 1.8 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.1 XP_011275172.1 - 0.15 12.0 0.0 0.37 10.7 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.1 XP_011275172.1 - 0.21 11.9 1.3 0.53 10.5 0.1 2.4 2 1 0 2 2 2 0 AAA domain TBCA PF02970.11 XP_011275173.1 - 3.3e-29 100.8 9.5 3.9e-29 100.5 6.6 1.0 1 0 0 1 1 1 1 Tubulin binding cofactor A DUF3867 PF12983.2 XP_011275173.1 - 0.009 16.0 1.1 0.01 15.8 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3867) WHEP-TRS PF00458.15 XP_011275173.1 - 0.017 14.7 3.4 0.039 13.6 2.4 1.6 1 0 0 1 1 1 0 WHEP-TRS domain PSII_Pbs27 PF13326.1 XP_011275173.1 - 0.024 14.6 0.1 0.032 14.2 0.1 1.3 1 1 0 1 1 1 0 Photosystem II Pbs27 DASH_Duo1 PF08651.5 XP_011275173.1 - 0.066 12.8 0.8 0.12 11.9 0.2 1.8 2 0 0 2 2 2 0 DASH complex subunit Duo1 DUF342 PF03961.8 XP_011275173.1 - 0.089 11.1 7.2 0.094 11.1 5.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Dna2 PF08696.6 XP_011275173.1 - 0.094 12.0 0.9 0.1 11.8 0.6 1.1 1 0 0 1 1 1 0 DNA replication factor Dna2 4HB_MCP_1 PF12729.2 XP_011275173.1 - 0.14 11.5 4.8 0.17 11.2 3.3 1.1 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction DUF2031 PF09592.5 XP_011275173.1 - 0.15 11.1 3.0 0.16 11.1 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) Sas10_Utp3 PF04000.10 XP_011275173.1 - 0.16 12.1 0.4 0.16 12.1 0.3 2.1 1 1 1 2 2 2 0 Sas10/Utp3/C1D family zf-C4H2 PF10146.4 XP_011275173.1 - 0.24 11.4 6.5 0.29 11.1 4.5 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein Phage_GP20 PF06810.6 XP_011275173.1 - 0.34 10.3 12.1 6.3 6.2 8.3 2.0 1 1 0 1 1 1 0 Phage minor structural protein GP20 DUF2361 PF10153.4 XP_011275173.1 - 1.1 9.4 5.7 1.3 9.2 3.9 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2361) Prefoldin PF02996.12 XP_011275174.1 - 8.3e-15 54.4 3.2 8.3e-15 54.4 2.2 2.5 3 0 0 3 3 3 1 Prefoldin subunit DUF3835 PF12927.2 XP_011275174.1 - 6.4e-09 36.6 2.7 6.4e-09 36.6 1.8 11.3 8 3 1 9 9 9 2 Domain of unknown function (DUF3835) Tho2 PF11262.3 XP_011275175.1 - 0.11 11.4 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF506 PF04720.7 XP_011275175.1 - 1.9 8.0 5.4 1 8.9 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF506) RNA_pol_Rpc4 PF05132.9 XP_011275175.1 - 4.6 7.2 6.7 0.76 9.7 0.4 2.3 3 0 0 3 3 3 0 RNA polymerase III RPC4 Methyltransf_12 PF08242.7 XP_011275177.1 - 1.3e-16 60.8 0.4 6.4e-16 58.6 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.1 XP_011275177.1 - 6.9e-16 58.3 0.0 9.4e-16 57.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 XP_011275177.1 - 5.9e-11 42.6 0.0 1.3e-10 41.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 XP_011275177.1 - 1.8e-09 37.9 0.0 5.2e-09 36.4 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 XP_011275177.1 - 2.7e-09 36.7 0.0 6.6e-09 35.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 XP_011275177.1 - 1.2e-08 35.5 0.0 3.4e-08 34.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 XP_011275177.1 - 1.2e-05 25.3 0.0 2.3e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 XP_011275177.1 - 0.00095 18.2 0.0 0.16 10.9 0.0 2.2 2 0 0 2 2 2 2 NNMT/PNMT/TEMT family DUF3419 PF11899.3 XP_011275177.1 - 0.0044 15.7 0.0 0.0072 15.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_8 PF05148.10 XP_011275177.1 - 0.0067 16.0 0.0 1.3 8.6 0.0 2.3 2 0 0 2 2 2 1 Hypothetical methyltransferase TPMT PF05724.6 XP_011275177.1 - 0.018 14.4 0.1 0.66 9.3 0.0 2.8 2 1 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) RHSP PF07999.6 XP_011275177.1 - 0.025 13.2 0.0 0.041 12.4 0.0 1.3 1 0 0 1 1 1 0 Retrotransposon hot spot protein APG5 PF04106.7 XP_011275178.1 - 6.1e-55 185.7 0.1 6.7e-55 185.6 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Apg5 SGT1 PF07093.6 XP_011275179.1 - 8.6e-55 186.2 34.3 1.1e-50 172.6 0.7 2.1 1 1 1 2 2 2 2 SGT1 protein Pkinase PF00069.20 XP_011275180.1 - 5e-69 232.3 0.1 5e-69 232.3 0.1 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011275180.1 - 1.2e-39 136.0 0.0 1.9e-39 135.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 XP_011275180.1 - 4.8e-06 25.7 0.0 1.2e-05 24.4 0.0 1.6 2 0 0 2 2 2 1 Kinase-like AvrB_AvrC PF05394.6 XP_011275180.1 - 0.0027 16.7 2.9 0.0041 16.1 1.5 1.6 1 1 0 1 1 1 1 Avirulence protein Kdo PF06293.9 XP_011275180.1 - 0.021 13.8 0.0 0.077 12.0 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mur_ligase_M PF08245.7 XP_011275181.1 - 2.4e-07 31.0 0.6 1.8e-05 24.9 0.4 2.6 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.16 XP_011275181.1 - 0.0017 18.3 0.0 0.0036 17.2 0.0 1.6 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain DcpS_C PF11969.3 XP_011275182.1 - 5.2e-23 81.4 4.2 5.4e-23 81.4 1.7 1.8 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 XP_011275182.1 - 1.9e-18 66.7 0.6 2.3e-17 63.2 0.1 2.2 2 0 0 2 2 2 1 HIT domain zf-C2H2_4 PF13894.1 XP_011275182.1 - 0.0064 16.7 0.1 0.027 14.7 0.1 2.1 1 0 0 1 1 1 1 C2H2-type zinc finger ENT PF03735.9 XP_011275182.1 - 0.017 14.8 0.2 0.055 13.1 0.2 1.9 2 0 0 2 2 2 0 ENT domain zf-BED PF02892.10 XP_011275182.1 - 0.04 13.6 0.8 0.04 13.6 0.5 1.7 2 0 0 2 2 2 0 BED zinc finger WGG PF10273.4 XP_011275182.1 - 0.073 13.1 0.9 7.7 6.6 0.0 2.3 2 0 0 2 2 2 0 Pre-rRNA-processing protein TSR2 YafO_toxin PF13957.1 XP_011275182.1 - 0.078 12.7 1.0 0.21 11.4 0.7 1.8 1 1 0 1 1 1 0 Toxin YafO, type II toxin-antitoxin system ROS_MUCR PF05443.6 XP_011275182.1 - 0.088 12.5 0.3 0.23 11.2 0.2 1.7 1 0 0 1 1 1 0 ROS/MUCR transcriptional regulator protein RAMPs PF03787.10 XP_011275182.1 - 2.8 7.7 5.7 1 9.1 0.6 2.0 2 0 0 2 2 2 0 RAMP superfamily AAA PF00004.24 XP_011275183.1 - 1.8e-43 147.8 0.0 3.4e-43 147.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 XP_011275183.1 - 2.9e-07 30.2 0.1 1.7e-05 24.5 0.1 3.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 XP_011275183.1 - 4.1e-07 30.1 0.0 2.2e-05 24.5 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.9 XP_011275183.1 - 4e-06 26.8 0.0 8.1e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 XP_011275183.1 - 1.5e-05 25.1 0.1 0.0025 17.9 0.1 2.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 XP_011275183.1 - 3.3e-05 23.0 0.0 7.1e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 XP_011275183.1 - 0.0001 22.0 0.0 0.00023 20.8 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain UPF0079 PF02367.12 XP_011275183.1 - 0.00036 20.1 0.0 0.00069 19.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_17 PF13207.1 XP_011275183.1 - 0.00045 21.0 0.5 0.0014 19.4 0.1 2.1 2 1 0 2 2 1 1 AAA domain TIP49 PF06068.8 XP_011275183.1 - 0.0021 16.8 0.0 0.0036 16.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus RNA_helicase PF00910.17 XP_011275183.1 - 0.0026 17.9 0.0 0.0055 16.8 0.0 1.6 1 0 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.12 XP_011275183.1 - 0.0028 17.1 0.0 0.0053 16.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 XP_011275183.1 - 0.0035 17.2 0.0 0.0073 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 XP_011275183.1 - 0.0051 16.0 0.1 0.01 15.0 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 XP_011275183.1 - 0.0052 16.6 0.0 0.019 14.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 XP_011275183.1 - 0.0061 15.9 0.5 0.027 13.8 0.2 2.0 1 1 0 2 2 2 1 AAA domain AAA_28 PF13521.1 XP_011275183.1 - 0.0089 15.9 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 XP_011275183.1 - 0.012 15.2 0.4 0.023 14.2 0.3 1.4 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 XP_011275183.1 - 0.014 14.4 0.0 0.12 11.5 0.0 2.4 2 0 0 2 2 2 0 KaiC AAA_18 PF13238.1 XP_011275183.1 - 0.014 15.6 0.0 0.056 13.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF4200 PF13863.1 XP_011275183.1 - 0.031 14.2 0.5 0.067 13.1 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) PhoH PF02562.11 XP_011275183.1 - 0.035 13.3 0.1 0.063 12.5 0.1 1.3 1 0 0 1 1 1 0 PhoH-like protein Zeta_toxin PF06414.7 XP_011275183.1 - 0.05 12.6 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_3 PF07726.6 XP_011275183.1 - 0.07 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 XP_011275183.1 - 0.07 12.7 0.1 0.28 10.8 0.0 1.9 1 1 1 2 2 2 0 NACHT domain Parvo_NS1 PF01057.12 XP_011275183.1 - 0.072 11.9 0.1 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF815 PF05673.8 XP_011275183.1 - 0.072 11.9 0.0 0.23 10.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.21 XP_011275183.1 - 0.099 12.1 0.1 0.45 9.9 0.0 2.0 2 1 0 2 2 2 0 Sigma-54 interaction domain Hexapep PF00132.19 XP_011275184.1 - 7.2e-10 37.9 2.5 0.00049 19.4 0.2 3.5 1 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 XP_011275184.1 - 1.6e-07 31.5 0.0 2.3e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.18 XP_011275184.1 - 2.8e-05 23.5 0.0 0.0001 21.6 0.0 1.9 1 1 0 1 1 1 1 Nucleotidyl transferase Hexapep_2 PF14602.1 XP_011275184.1 - 0.00039 19.9 2.8 0.13 11.8 0.8 3.2 1 1 1 2 2 2 2 Hexapeptide repeat of succinyl-transferase CTP_transf_3 PF02348.14 XP_011275184.1 - 0.0044 16.6 0.0 0.024 14.2 0.0 2.1 2 0 0 2 2 2 1 Cytidylyltransferase CENP-B_dimeris PF09026.5 XP_011275184.1 - 0.88 9.8 9.8 2.5 8.3 6.8 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain tRNA-synt_1 PF00133.17 XP_011275185.1 - 2.5e-45 154.5 0.0 9.6e-37 126.2 0.0 2.7 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 XP_011275185.1 - 6.5e-19 67.8 3.2 4.3e-11 42.1 0.0 4.3 5 0 0 5 5 5 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 XP_011275185.1 - 1.7e-13 50.5 0.2 5.2e-13 49.0 0.0 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 XP_011275185.1 - 3.2e-07 29.7 0.0 7.1e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1_2 PF13603.1 XP_011275185.1 - 0.0032 16.8 0.1 0.08 12.2 0.0 3.0 3 0 0 3 3 3 1 Leucyl-tRNA synthetase, Domain 2 adh_short PF00106.20 XP_011275186.1 - 1.2e-13 51.2 0.0 4.2e-13 49.5 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 XP_011275186.1 - 0.0024 17.6 0.0 0.0037 17.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 XP_011275186.1 - 0.099 12.3 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 KR domain KOW PF00467.24 XP_011275187.1 - 0.11 12.3 1.1 0.17 11.6 0.2 1.8 2 0 0 2 2 2 0 KOW motif Herp-Cyclin PF09241.5 XP_011275187.1 - 0.16 12.3 0.0 0.3 11.4 0.0 1.4 1 0 0 1 1 1 0 Herpesviridae viral cyclin EF-hand_7 PF13499.1 XP_011275188.1 - 7.9e-13 48.3 3.4 1.4e-10 41.1 1.8 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 XP_011275188.1 - 9.4e-13 47.5 6.7 5.2e-08 32.3 0.3 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 XP_011275188.1 - 2.6e-12 45.0 8.4 1.3e-05 24.1 0.0 3.2 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 XP_011275188.1 - 1e-10 40.5 7.0 1.3e-06 27.7 0.1 3.3 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.1 XP_011275188.1 - 5.2e-08 31.8 13.7 5.6e-05 22.2 0.1 3.7 3 1 1 4 4 4 3 EF hand AsiA PF09010.5 XP_011275188.1 - 0.017 15.0 0.2 0.86 9.5 0.0 2.2 2 0 0 2 2 2 0 Anti-Sigma Factor A MgtE_N PF03448.12 XP_011275188.1 - 0.022 15.0 3.1 0.023 15.0 0.2 1.9 1 1 0 2 2 2 0 MgtE intracellular N domain MerR-DNA-bind PF09278.6 XP_011275188.1 - 0.025 14.9 0.9 6.3 7.2 0.1 2.6 2 1 0 2 2 2 0 MerR, DNA binding EF-hand_9 PF14658.1 XP_011275188.1 - 0.04 13.8 0.2 0.076 12.9 0.0 1.6 2 0 0 2 2 2 0 EF-hand domain H-kinase_dim PF02895.9 XP_011275188.1 - 0.097 13.0 1.7 0.27 11.5 0.1 2.1 1 1 1 2 2 2 0 Signal transducing histidine kinase, homodimeric domain CAP_GLY PF01302.20 XP_011275189.1 - 1.8e-23 82.0 0.9 3.3e-23 81.1 0.6 1.4 1 0 0 1 1 1 1 CAP-Gly domain HALZ PF02183.13 XP_011275189.1 - 0.0037 16.9 2.2 0.0037 16.9 1.5 8.2 6 4 1 7 7 7 2 Homeobox associated leucine zipper DUF869 PF05911.6 XP_011275189.1 - 0.67 8.1 86.5 1.8 6.6 11.7 3.1 2 1 1 3 3 3 0 Plant protein of unknown function (DUF869) RPW8 PF05659.6 XP_011275189.1 - 0.79 9.2 26.0 0.1 12.1 3.1 3.8 3 2 1 4 4 4 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Glycos_transf_1 PF00534.15 XP_011275190.1 - 1.4e-29 102.7 0.0 1.9e-29 102.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 PIGA PF08288.7 XP_011275190.1 - 7e-18 64.7 2.6 2e-17 63.3 1.8 1.8 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glyco_trans_1_4 PF13692.1 XP_011275190.1 - 2.4e-11 43.8 0.0 4e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 XP_011275190.1 - 3.5e-07 30.0 0.0 8.8e-06 25.5 0.0 2.2 1 1 1 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.1 XP_011275190.1 - 0.00018 21.7 0.0 0.00031 20.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 XP_011275190.1 - 0.015 15.4 0.0 0.023 14.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain TFR_dimer PF04253.10 XP_011275191.1 - 1.4e-32 111.9 0.0 2.6e-32 111.0 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.17 XP_011275191.1 - 4.9e-05 22.9 0.0 0.0018 17.9 0.0 2.3 2 0 0 2 2 2 1 PA domain KH_3 PF13014.1 XP_011275191.1 - 0.16 11.6 0.0 0.47 10.1 0.0 1.7 1 0 0 1 1 1 0 KH domain Cyt-b5 PF00173.23 XP_011275192.1 - 6.3e-12 45.1 0.0 8.2e-12 44.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acetyltransf_1 PF00583.19 XP_011275193.1 - 4.3e-11 42.6 0.0 6.3e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 XP_011275193.1 - 1.1e-07 31.8 0.0 1.7e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 XP_011275193.1 - 8.1e-07 29.1 0.0 1.1e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 XP_011275193.1 - 0.00015 21.8 0.0 0.00019 21.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 XP_011275193.1 - 0.1 12.4 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Sec63 PF02889.11 XP_011275194.1 - 1.8e-17 63.5 2.5 3.1e-15 56.1 0.3 2.2 1 1 1 2 2 2 2 Sec63 Brl domain DnaJ PF00226.26 XP_011275194.1 - 2.6e-16 59.0 0.9 7.2e-16 57.6 0.6 1.8 1 0 0 1 1 1 1 DnaJ domain TAP_C PF03943.8 XP_011275195.1 - 1.7e-13 49.7 1.4 2.3e-13 49.3 0.2 1.9 2 0 0 2 2 2 1 TAP C-terminal domain LRR_4 PF12799.2 XP_011275195.1 - 6.8e-09 35.1 4.0 1.5e-05 24.5 3.0 3.1 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 XP_011275195.1 - 0.00018 21.0 0.1 0.0004 20.0 0.1 1.5 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.1 XP_011275195.1 - 0.00054 19.6 1.5 0.002 17.8 1.0 2.1 1 0 0 1 1 1 1 Leucine rich repeat NTF2 PF02136.15 XP_011275195.1 - 0.00056 20.2 0.6 0.36 11.1 0.4 2.9 2 1 0 2 2 2 2 Nuclear transport factor 2 (NTF2) domain LRR_1 PF00560.28 XP_011275195.1 - 0.0051 16.6 1.5 67 4.1 0.1 4.6 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_6 PF13516.1 XP_011275195.1 - 0.0076 16.2 2.0 42 4.6 0.2 4.0 3 0 0 3 3 3 0 Leucine Rich repeat LRR_7 PF13504.1 XP_011275195.1 - 0.036 14.2 0.6 20 5.9 0.1 3.6 3 0 0 3 3 3 0 Leucine rich repeat MFS_1 PF07690.11 XP_011275196.1 - 1.4e-27 96.4 35.5 1.4e-27 96.4 24.6 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF2986 PF11661.3 XP_011275196.1 - 0.48 10.7 3.4 21 5.5 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2986) Mem_trans PF03547.13 XP_011275197.1 - 4.6e-54 183.1 8.4 5.6e-54 182.8 5.8 1.0 1 0 0 1 1 1 1 Membrane transport protein DUF1129 PF06570.6 XP_011275197.1 - 0.021 14.1 0.4 0.021 14.1 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DUF2217 PF10265.4 XP_011275197.1 - 0.43 9.2 4.4 0.61 8.7 3.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Mito_carr PF00153.22 XP_011275199.1 - 2.3e-67 222.7 4.6 3.3e-23 81.2 0.1 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein Exo5 PF09810.4 XP_011275200.1 - 2.7e-40 138.5 0.1 1.2e-39 136.4 0.1 1.9 1 1 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.2 XP_011275200.1 - 0.00086 18.7 1.4 0.004 16.5 1.0 2.1 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily SWIRM PF04433.12 XP_011275201.1 - 2.8e-33 113.9 0.0 8.2e-33 112.3 0.0 1.9 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 XP_011275201.1 - 5.9e-10 39.0 0.2 1.5e-09 37.7 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 XP_011275201.1 - 7e-08 32.4 0.1 2.8e-07 30.5 0.0 2.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF1848 PF08902.6 XP_011275201.1 - 0.068 12.6 0.2 0.19 11.2 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1848) CASP_C PF08172.7 XP_011275202.1 - 2.6e-67 226.4 8.5 2.6e-67 226.4 5.9 4.1 4 2 0 4 4 4 1 CASP C terminal MCP_N PF05581.7 XP_011275202.1 - 0.11 12.7 1.6 0.38 10.9 0.0 2.7 3 0 0 3 3 3 0 Vibrio chemotaxis protein N terminus Ribosomal_L22 PF00237.14 XP_011275203.1 - 1.5e-32 111.6 0.2 2e-32 111.2 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e ATG27 PF09451.5 XP_011275204.1 - 3.4e-49 167.4 0.5 4.5e-49 167.0 0.3 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.13 XP_011275204.1 - 0.066 12.9 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 Cation-independent mannose-6-phosphate receptor repeat Prefoldin_2 PF01920.15 XP_011275205.1 - 1.9e-11 43.6 7.3 2.1e-11 43.5 5.1 1.0 1 0 0 1 1 1 1 Prefoldin subunit ShlB PF03865.8 XP_011275205.1 - 0.06 12.0 0.1 0.087 11.5 0.1 1.2 1 0 0 1 1 1 0 Haemolysin secretion/activation protein ShlB/FhaC/HecB ATP12 PF07542.6 XP_011275206.1 - 8.5e-34 116.1 0.0 1.6e-33 115.2 0.0 1.4 1 0 0 1 1 1 1 ATP12 chaperone protein PCI PF01399.22 XP_011275208.1 - 1.2e-07 31.9 1.5 1.2e-07 31.9 1.1 2.6 2 0 0 2 2 2 1 PCI domain Gon7 PF08738.5 XP_011275209.1 - 4.5e-31 106.9 1.2 5.2e-31 106.6 0.8 1.0 1 0 0 1 1 1 1 Gon7 family Arena_RNA_pol PF06317.6 XP_011275209.1 - 0.12 8.9 0.0 0.14 8.7 0.0 1.0 1 0 0 1 1 1 0 Arenavirus RNA polymerase Glyco_transf_34 PF05637.7 XP_011275210.1 - 8.4e-57 192.4 0.1 1.2e-56 191.8 0.0 1.3 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family O-ag_pol_Wzy PF14296.1 XP_011275210.1 - 0.28 9.7 7.0 0.026 13.1 1.4 1.7 2 0 0 2 2 2 0 O-antigen polysaccharide polymerase Wzy MFS_1 PF07690.11 XP_011275211.1 - 2.1e-05 23.4 52.7 0.0079 14.9 32.1 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 XP_011275211.1 - 0.0031 16.1 12.5 0.0031 16.1 8.7 3.1 2 1 0 3 3 3 1 Sugar (and other) transporter HSP90 PF00183.13 XP_011275212.1 - 1e-251 835.9 41.7 1.3e-251 835.6 28.9 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 XP_011275212.1 - 2e-11 43.5 0.1 3.8e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 XP_011275212.1 - 3.7e-11 42.8 0.1 3.7e-11 42.8 0.1 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RNA_pol_Rpb1_5 PF04998.12 XP_011275212.1 - 6.3 5.9 7.0 20 4.2 4.8 2.0 1 1 0 1 1 1 0 RNA polymerase Rpb1, domain 5 TBCC PF07986.7 XP_011275213.1 - 2.9e-11 42.8 0.0 3.8e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor C Adaptin_binding PF10199.4 XP_011275213.1 - 0.076 13.2 0.2 0.087 13.1 0.1 1.2 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Spc24 PF08286.6 XP_011275214.1 - 1.7 8.3 29.5 0.22 11.2 5.3 3.1 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 RasGAP_C PF03836.10 XP_011275215.1 - 5.4e-40 136.3 9.8 3.1e-39 133.9 6.8 2.5 1 0 0 1 1 1 1 RasGAP C-terminus RasGAP PF00616.14 XP_011275215.1 - 4.7e-21 75.3 5.1 4.7e-21 75.3 3.6 3.9 4 1 0 4 4 4 1 GTPase-activator protein for Ras-like GTPase CH PF00307.26 XP_011275215.1 - 1.3e-11 44.5 0.0 3.5e-10 39.8 0.0 3.1 2 0 0 2 2 2 1 Calponin homology (CH) domain IQ PF00612.22 XP_011275215.1 - 1.2e-08 33.8 22.2 0.85 9.4 0.0 10.0 11 0 0 11 11 11 3 IQ calmodulin-binding motif CAMSAP_CH PF11971.3 XP_011275215.1 - 0.0062 16.1 0.0 0.064 12.9 0.0 2.8 3 0 0 3 3 3 1 CAMSAP CH domain DUF1619 PF07773.6 XP_011275215.1 - 0.0095 15.7 0.7 0.036 13.8 0.5 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1619) zf-met PF12874.2 XP_011275216.1 - 0.027 14.6 0.1 0.061 13.5 0.1 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 XP_011275216.1 - 0.044 14.1 0.3 0.12 12.7 0.2 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.21 XP_011275216.1 - 0.065 13.5 0.5 0.18 12.2 0.4 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF2256 PF10013.4 XP_011275216.1 - 0.13 12.0 0.3 0.26 11.0 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) RINGv PF12906.2 XP_011275217.1 - 0.00049 20.0 0.7 0.0013 18.7 0.5 1.7 1 0 0 1 1 1 1 RING-variant domain Cnd2 PF05786.9 XP_011275217.1 - 0.0097 14.4 10.0 0.0099 14.4 6.2 1.5 1 1 0 1 1 1 1 Condensin complex subunit 2 zf-RING_2 PF13639.1 XP_011275217.1 - 0.012 15.4 3.8 0.04 13.7 2.6 1.9 1 1 0 1 1 1 0 Ring finger domain TRAP_alpha PF03896.11 XP_011275217.1 - 0.045 12.7 5.1 0.097 11.6 3.5 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Spot_14 PF07084.7 XP_011275217.1 - 0.059 13.2 1.5 0.15 11.9 1.1 1.6 1 0 0 1 1 1 0 Thyroid hormone-inducible hepatic protein Spot 14 Daxx PF03344.10 XP_011275217.1 - 0.099 11.1 12.2 0.14 10.5 8.5 1.2 1 0 0 1 1 1 0 Daxx Family FANCL_C PF11793.3 XP_011275217.1 - 0.27 11.2 3.1 0.36 10.8 0.4 2.2 2 0 0 2 2 2 0 FANCL C-terminal domain DUF2457 PF10446.4 XP_011275217.1 - 1.1 7.9 15.3 0.31 9.7 8.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) DUF1676 PF07898.8 XP_011275217.1 - 2.1 8.6 7.8 0.47 10.7 1.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1676) CDC45 PF02724.9 XP_011275217.1 - 2.7 5.9 11.1 0.19 9.7 3.9 1.7 2 0 0 2 2 2 0 CDC45-like protein Mpp10 PF04006.7 XP_011275217.1 - 3.4 5.9 25.9 0.073 11.4 13.4 1.5 2 0 0 2 2 2 0 Mpp10 protein Nucleoplasmin PF03066.10 XP_011275217.1 - 3.7 7.0 20.2 8.2 5.9 14.0 1.6 1 0 0 1 1 1 0 Nucleoplasmin YqfQ PF14181.1 XP_011275217.1 - 4.9 7.1 7.2 13 5.7 5.0 1.7 1 0 0 1 1 1 0 YqfQ-like protein NOA36 PF06524.7 XP_011275217.1 - 7.9 5.6 7.2 15 4.7 5.0 1.3 1 0 0 1 1 1 0 NOA36 protein CobT PF06213.7 XP_011275217.1 - 8.7 5.3 15.6 14 4.7 10.8 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RIG-I_C-RD PF11648.3 XP_011275218.1 - 0.0012 18.7 0.1 0.003 17.4 0.1 1.6 1 0 0 1 1 1 1 C-terminal domain of RIG-I Cobl PF09469.5 XP_011275219.1 - 0.8 9.7 0.0 0.8 9.7 0.0 3.9 3 1 1 4 4 4 0 Cordon-bleu ubiquitin-like domain UAA PF08449.6 XP_011275220.1 - 1.1e-71 241.2 22.3 1.4e-71 240.9 15.4 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 XP_011275220.1 - 3.9e-08 33.0 8.4 3.9e-08 33.0 5.8 2.4 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 XP_011275220.1 - 1.6e-05 24.9 8.5 1.6e-05 24.9 5.9 3.9 4 1 0 4 4 4 2 EamA-like transporter family EmrE PF13536.1 XP_011275220.1 - 0.0004 20.5 19.9 0.0021 18.2 3.0 2.7 3 0 0 3 3 3 2 Multidrug resistance efflux transporter DUF1749 PF08538.5 XP_011275221.1 - 1.7e-101 339.1 0.1 1.8e-101 339.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 XP_011275221.1 - 1.1e-11 45.0 0.0 1.5e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 XP_011275221.1 - 7.5e-08 32.2 0.0 4.9e-07 29.6 0.0 2.2 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 XP_011275221.1 - 2.8e-06 27.0 0.0 0.00011 21.8 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold LCAT PF02450.10 XP_011275221.1 - 7e-05 21.9 0.0 9.7e-05 21.4 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Ser_hydrolase PF06821.8 XP_011275221.1 - 0.0033 17.0 0.0 0.0072 15.9 0.0 1.5 2 0 0 2 2 2 1 Serine hydrolase Abhydrolase_3 PF07859.8 XP_011275221.1 - 0.05 13.1 0.0 0.25 10.8 0.0 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 XP_011275221.1 - 0.061 12.7 0.6 3.1 7.1 0.1 2.3 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase DUF2435 PF10363.4 XP_011275223.1 - 0.00077 19.3 1.1 0.0047 16.7 0.3 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) AOX PF01786.12 XP_011275223.1 - 0.098 12.0 1.3 0.12 11.7 0.9 1.3 1 1 0 1 1 1 0 Alternative oxidase DUF3914 PF13053.1 XP_011275227.1 - 0.14 12.2 0.8 0.24 11.5 0.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3914) DUF3447 PF11929.3 XP_011275229.1 - 0.29 10.9 0.2 0.29 10.9 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3447) DIM1 PF02966.11 XP_011275231.1 - 0.0037 16.7 0.0 0.004 16.6 0.0 1.1 1 0 0 1 1 1 1 Mitosis protein DIM1 LemA PF04011.7 XP_011275233.1 - 0.012 14.7 0.1 0.017 14.1 0.1 1.2 1 0 0 1 1 1 0 LemA family NCD1 PF04904.8 XP_011275234.1 - 0.047 13.4 1.7 3.3 7.5 0.1 2.6 2 1 1 3 3 3 0 NAB conserved region 1 (NCD1) DUF1292 PF06949.6 XP_011275234.1 - 1.2 9.5 5.2 0.68 10.3 0.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1292) SpoU_sub_bind PF08032.7 XP_011275235.1 - 0.01 15.9 0.1 0.019 15.1 0.1 1.5 1 0 0 1 1 1 0 RNA 2'-O ribose methyltransferase substrate binding DUF3615 PF12274.3 XP_011275235.1 - 0.078 13.3 0.9 0.27 11.5 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3615) DUF1749 PF08538.5 XP_011275236.1 - 2.2e-97 325.6 0.0 2.4e-97 325.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 XP_011275236.1 - 1.2e-11 44.8 0.0 1.6e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 XP_011275236.1 - 8.4e-08 32.0 0.0 3.4e-07 30.1 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 XP_011275236.1 - 1e-06 28.4 0.0 4.7e-06 26.3 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 XP_011275236.1 - 0.0025 17.4 0.0 0.0082 15.7 0.0 1.7 2 0 0 2 2 2 1 Serine hydrolase LCAT PF02450.10 XP_011275236.1 - 0.0034 16.4 0.0 0.005 15.8 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_3 PF07859.8 XP_011275236.1 - 0.0083 15.7 0.0 0.16 11.5 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF900 PF05990.7 XP_011275236.1 - 0.013 14.8 0.0 0.047 13.0 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) DUF3530 PF12048.3 XP_011275236.1 - 0.037 13.0 0.0 0.11 11.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3530) Abhydrolase_2 PF02230.11 XP_011275236.1 - 0.13 11.6 0.1 11 5.3 0.0 2.2 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase COesterase PF00135.23 XP_011275237.1 - 8.6e-100 334.9 0.0 1e-99 334.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 XP_011275237.1 - 0.00032 20.3 0.1 0.0026 17.3 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 XP_011275237.1 - 0.0072 15.5 0.0 0.014 14.6 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Aminotran_1_2 PF00155.16 XP_011275238.1 - 2.4e-19 69.5 0.0 2.1e-18 66.4 0.0 2.3 1 1 0 1 1 1 1 Aminotransferase class I and II Bac_luciferase PF00296.15 XP_011275239.1 - 2.1e-43 148.6 0.0 3e-43 148.1 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase BLOC1_2 PF10046.4 XP_011275239.1 - 0.073 13.2 0.2 0.16 12.1 0.1 1.5 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 WSC PF01822.14 XP_011275240.1 - 4.7e-15 55.2 15.8 4.7e-15 55.2 10.9 3.6 2 1 0 2 2 2 1 WSC domain EphA2_TM PF14575.1 XP_011275240.1 - 0.12 12.8 0.0 0.8 10.1 0.0 2.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF912 PF06024.7 XP_011275240.1 - 0.17 11.9 0.0 0.17 11.9 0.0 3.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) KAR9 PF08580.5 XP_011275240.1 - 0.94 7.6 44.4 1.7 6.8 30.7 1.4 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Rax2 PF12768.2 XP_011275240.1 - 3.9 6.6 30.5 11 5.1 21.1 1.9 1 1 0 1 1 1 0 Cortical protein marker for cell polarity Potyvirid-P3 PF13608.1 XP_011275240.1 - 9.1 5.2 14.9 16 4.4 10.3 1.3 1 0 0 1 1 1 0 Protein P3 of Potyviral polyprotein HTH_Tnp_Tc5 PF03221.11 XP_011275241.1 - 0.015 15.0 1.3 0.061 13.1 0.9 2.1 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain DUF4248 PF14053.1 XP_011275241.1 - 0.07 12.7 0.2 2 8.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4248) Aminotran_1_2 PF00155.16 XP_011275243.1 - 9.9e-12 44.4 0.0 1.2e-08 34.2 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II zf-H2C2_2 PF13465.1 XP_011275244.1 - 3.9e-06 26.8 17.8 0.00025 21.1 4.8 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 XP_011275244.1 - 4.8e-05 23.4 16.6 0.01 16.0 3.5 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 XP_011275244.1 - 0.00034 20.7 18.5 0.041 14.2 3.4 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger DUF3698 PF12479.3 XP_011275245.1 - 0.68 10.0 7.1 12 6.0 0.8 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3698) ADK PF00406.17 XP_011275246.1 - 1.3e-58 197.1 0.0 1.7e-58 196.7 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 XP_011275246.1 - 1e-14 53.8 0.0 2.9e-14 52.4 0.0 1.8 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_33 PF13671.1 XP_011275246.1 - 0.0002 21.2 0.0 0.00034 20.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 XP_011275246.1 - 0.00023 21.4 0.0 0.00059 20.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 XP_011275246.1 - 0.00092 20.0 0.0 0.0015 19.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain PspB PF06667.7 XP_011275246.1 - 0.094 12.6 0.4 0.32 10.9 0.1 1.9 2 0 0 2 2 2 0 Phage shock protein B Zeta_toxin PF06414.7 XP_011275246.1 - 0.1 11.7 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin adh_short PF00106.20 XP_011275247.1 - 1.4e-30 106.3 0.1 2e-30 105.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 XP_011275247.1 - 5.6e-24 85.2 0.2 6.8e-24 84.9 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 XP_011275247.1 - 1.2e-14 54.4 0.0 1.6e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.14 XP_011275247.1 - 0.0035 16.4 1.1 0.0092 15.0 0.8 1.7 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.16 XP_011275247.1 - 0.024 14.0 0.2 0.032 13.6 0.1 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 XP_011275247.1 - 0.025 13.7 0.1 0.034 13.2 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) F420_oxidored PF03807.12 XP_011275247.1 - 0.1 13.0 0.3 0.3 11.5 0.1 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DUF3583 PF12126.3 XP_011275248.1 - 0.016 14.3 0.1 0.023 13.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3583) CFIA_Pcf11 PF11526.3 XP_011275249.1 - 3.2e-06 27.2 11.8 2.3e-05 24.4 5.4 3.1 2 1 0 2 2 2 1 Subunit of cleavage factor IA Pcf11 Mito_carr PF00153.22 XP_011275250.1 - 5.1e-30 103.0 1.2 4.8e-15 55.0 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein VHS PF00790.14 XP_011275250.1 - 0.026 14.1 0.0 9.5 5.8 0.0 2.5 2 1 1 3 3 3 0 VHS domain Ribosomal_L10 PF00466.15 XP_011275251.1 - 1.3e-09 37.9 0.0 2.2e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 DUF2353 PF09789.4 XP_011275251.1 - 0.0095 15.2 0.5 0.023 13.9 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized coiled-coil protein (DUF2353) LigB PF02900.13 XP_011275253.1 - 8.1e-39 133.2 0.0 9.5e-39 133.0 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase DUF3767 PF12597.3 XP_011275254.1 - 2.3e-36 124.0 0.1 3.3e-36 123.5 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3767) DUF2530 PF10745.4 XP_011275254.1 - 0.071 13.0 0.7 0.31 11.0 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2530) TMEM141 PF15110.1 XP_011275254.1 - 0.084 13.1 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 TMEM141 protein family Transposase_21 PF02992.9 XP_011275255.1 - 1.2e-06 27.7 0.3 3.8e-06 26.1 0.2 1.8 1 0 0 1 1 1 1 Transposase family tnp2 TFIIA PF03153.8 XP_011275255.1 - 4 7.2 21.0 7.9 6.2 14.6 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit OPT PF03169.10 XP_011275256.1 - 3.6e-164 547.6 47.4 4.2e-164 547.4 32.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein FAD_binding_8 PF08022.7 XP_011275257.1 - 1.7e-18 66.4 0.0 3.8e-18 65.2 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 XP_011275257.1 - 7.2e-17 61.6 8.6 1.7e-16 60.4 2.3 2.5 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 XP_011275257.1 - 3.4e-11 43.2 0.2 5.5e-11 42.6 0.1 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.19 XP_011275257.1 - 0.005 16.9 0.0 0.014 15.5 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain FANCI_S1 PF14675.1 XP_011275258.1 - 0.0063 15.8 0.9 0.013 14.9 0.6 1.6 1 1 0 1 1 1 1 FANCI solenoid 1 DUF605 PF04652.11 XP_011275258.1 - 2.7 7.3 25.5 3.4 6.9 17.7 1.1 1 0 0 1 1 1 0 Vta1 like Ctr PF04145.10 XP_011275258.1 - 4.1 7.4 4.7 7.4 6.6 0.5 2.2 2 0 0 2 2 2 0 Ctr copper transporter family ESAG1 PF03238.8 XP_011275259.1 - 0.023 13.9 0.1 0.045 13.0 0.1 1.4 1 0 0 1 1 1 0 ESAG protein Acyltransferase PF01553.16 XP_011275260.1 - 7.6e-16 57.7 0.0 1e-14 54.0 0.0 2.2 1 1 0 1 1 1 1 Acyltransferase DUF3987 PF13148.1 XP_011275260.1 - 0.078 11.5 0.0 0.12 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Acyltransferase PF01553.16 XP_011275261.1 - 0.00026 20.4 0.0 0.0014 18.0 0.0 2.0 1 1 0 1 1 1 1 Acyltransferase TPK_B1_binding PF04265.9 XP_011275262.1 - 0.06 13.0 1.3 0.57 9.9 0.0 3.0 3 0 0 3 3 3 0 Thiamin pyrophosphokinase, vitamin B1 binding domain RBD-FIP PF09457.5 XP_011275262.1 - 0.067 12.9 0.7 0.29 10.9 0.0 2.3 2 0 0 2 2 2 0 FIP domain Vma12 PF11712.3 XP_011275265.1 - 0.01 15.5 0.1 0.014 15.0 0.0 1.2 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Glycophorin_A PF01102.13 XP_011275265.1 - 0.011 15.5 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 0 Glycophorin A Bul1_N PF04425.7 XP_011275265.1 - 0.012 14.2 0.9 0.014 13.9 0.6 1.0 1 0 0 1 1 1 0 Bul1 N terminus PXA PF02194.10 XP_011275265.1 - 0.042 13.4 0.1 0.062 12.8 0.1 1.2 1 0 0 1 1 1 0 PXA domain UPF0233 PF06781.7 XP_011275265.1 - 0.086 12.4 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0233) DUF4194 PF13835.1 XP_011275265.1 - 0.1 12.0 0.4 2.5 7.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4194) DUF4404 PF14357.1 XP_011275265.1 - 0.3 11.5 2.9 0.49 10.8 2.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4404) Baculo_11_kDa PF06143.6 XP_011275265.1 - 1.5 8.2 5.9 5 6.5 4.1 1.9 1 1 0 1 1 1 0 Baculovirus 11 kDa family Ammonium_transp PF00909.16 XP_011275266.1 - 1.1e-116 389.6 23.0 1.2e-116 389.4 16.0 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DDR PF08841.5 XP_011275268.1 - 0.25 10.1 0.0 0.39 9.4 0.0 1.2 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain MFS_1 PF07690.11 XP_011275269.1 - 2.7e-25 88.8 19.1 2.7e-25 88.8 13.3 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily WSS_VP PF12175.3 XP_011275269.1 - 0.0094 15.0 0.7 2.8 6.9 0.0 2.5 2 0 0 2 2 2 2 White spot syndrome virus structural envelope protein VP Copper-fist PF00649.13 XP_011275270.1 - 7.9e-06 24.9 0.8 1.7e-05 23.9 0.5 1.6 1 0 0 1 1 1 1 Copper fist DNA binding domain TCTP PF00838.12 XP_011275271.1 - 2.6e-25 89.3 2.0 4e-25 88.7 1.4 1.3 1 1 0 1 1 1 1 Translationally controlled tumour protein TauD PF02668.11 XP_011275272.1 - 7.1e-43 147.1 0.2 1e-42 146.6 0.2 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family adh_short PF00106.20 XP_011275274.1 - 5.6e-31 107.6 0.3 7.9e-31 107.2 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 XP_011275274.1 - 2.6e-17 63.4 0.0 4.3e-17 62.6 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 XP_011275274.1 - 8.7e-15 54.8 0.3 1.4e-14 54.2 0.2 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 XP_011275274.1 - 0.0007 19.0 0.0 0.001 18.5 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 XP_011275274.1 - 0.028 14.2 0.2 0.051 13.3 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3HCDH_N PF02737.13 XP_011275274.1 - 0.029 14.0 0.2 0.048 13.3 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 XP_011275274.1 - 0.037 13.4 0.0 0.069 12.5 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.14 XP_011275274.1 - 0.077 12.1 0.2 0.11 11.5 0.1 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Herpes_BLRF2 PF05812.7 XP_011275274.1 - 0.093 12.5 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein CW_binding_2 PF04122.7 XP_011275274.1 - 0.1 12.8 0.1 0.55 10.4 0.0 2.0 2 0 0 2 2 2 0 Putative cell wall binding repeat 2 ADH_N PF08240.7 XP_011275275.1 - 1.3e-26 92.4 0.3 2.7e-26 91.4 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 XP_011275275.1 - 2.5e-17 62.6 0.2 3.8e-17 62.0 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase YdfZ PF14001.1 XP_011275275.1 - 0.0097 16.1 0.6 0.028 14.6 0.0 2.0 2 0 0 2 2 2 1 YdfZ protein AlaDh_PNT_C PF01262.16 XP_011275275.1 - 0.049 13.2 0.6 0.049 13.2 0.4 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Dak1 PF02733.12 XP_011275276.1 - 2.5e-123 410.7 5.2 3.7e-123 410.2 3.6 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 XP_011275276.1 - 4.8e-48 163.1 2.1 1.5e-47 161.5 1.0 2.1 3 0 0 3 3 3 1 DAK2 domain PuR_N PF09182.5 XP_011275276.1 - 0.088 12.4 0.2 9.4 5.9 0.0 3.0 2 0 0 2 2 2 0 Bacterial purine repressor, N-terminal DHDPS PF00701.17 XP_011275277.1 - 1.6e-33 115.5 0.0 2.1e-33 115.1 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Fer4_12 PF13353.1 XP_011275277.1 - 0.1 12.7 0.0 0.17 11.9 0.0 1.4 1 1 0 1 1 1 0 4Fe-4S single cluster domain MR_MLE_C PF13378.1 XP_011275278.1 - 1.6e-30 105.3 0.0 2.4e-30 104.7 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.11 XP_011275278.1 - 2.6e-23 82.2 0.0 5.9e-23 81.0 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MR_MLE PF01188.16 XP_011275278.1 - 1.8e-10 41.1 0.0 3.7e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain DUF1990 PF09348.5 XP_011275278.1 - 0.12 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1990) FMO-like PF00743.14 XP_011275279.1 - 5.8e-23 80.8 0.3 2.1e-14 52.6 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 XP_011275279.1 - 4.3e-18 66.1 0.0 9.3e-18 65.0 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 XP_011275279.1 - 3.1e-10 40.2 0.0 2e-09 37.6 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 XP_011275279.1 - 9.5e-07 28.0 0.2 8.4e-05 21.6 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 XP_011275279.1 - 1.2e-05 25.2 0.0 7.1e-05 22.7 0.0 2.4 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 XP_011275279.1 - 1.3e-05 25.5 0.3 0.04 14.3 0.1 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 XP_011275279.1 - 2.7e-05 23.3 0.0 5.2e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 XP_011275279.1 - 0.00029 19.8 1.0 0.0088 14.9 0.1 2.5 3 0 0 3 3 3 1 Glucose inhibited division protein A DAO PF01266.19 XP_011275279.1 - 0.00061 18.7 0.0 0.0034 16.3 0.0 2.2 2 1 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 XP_011275279.1 - 0.00073 18.1 0.0 0.0012 17.3 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 XP_011275279.1 - 0.00082 18.3 0.2 0.0085 14.9 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 XP_011275279.1 - 0.012 15.3 0.8 4.1 7.1 0.1 3.2 2 1 1 3 3 3 0 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.14 XP_011275279.1 - 0.017 14.2 0.1 0.077 12.1 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 XP_011275279.1 - 0.019 14.5 0.0 0.037 13.5 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 XP_011275279.1 - 0.022 14.4 0.1 2.4 7.7 0.0 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 XP_011275279.1 - 0.031 14.3 0.3 2.7 8.1 0.1 2.6 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.9 XP_011275279.1 - 0.05 12.9 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Thi4 PF01946.12 XP_011275279.1 - 0.063 12.3 0.0 0.16 11.0 0.0 1.6 1 0 0 1 1 1 0 Thi4 family adh_short_C2 PF13561.1 XP_011275280.1 - 1.2e-17 64.4 0.1 2.1e-17 63.6 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 XP_011275280.1 - 8.7e-17 61.5 0.1 2.2e-16 60.1 0.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 XP_011275280.1 - 3.2e-09 36.7 0.0 5.1e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 XP_011275280.1 - 0.0012 17.5 1.0 0.0017 17.0 0.7 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Aldo_ket_red PF00248.16 XP_011275281.1 - 7.7e-46 156.1 0.0 9.7e-46 155.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Sugar_tr PF00083.19 XP_011275282.1 - 1.2e-98 330.6 31.1 1.4e-98 330.4 21.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 XP_011275282.1 - 1.6e-21 76.4 36.3 3.6e-21 75.2 24.1 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily PLDc_N PF13396.1 XP_011275282.1 - 0.013 15.1 3.8 0.013 15.1 2.6 3.5 4 1 1 5 5 5 0 Phospholipase_D-nuclease N-terminal DUF4293 PF14126.1 XP_011275282.1 - 0.83 9.5 7.6 0.41 10.5 3.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) Zn_clus PF00172.13 XP_011275283.1 - 2e-06 27.5 8.7 3.7e-06 26.7 6.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 XP_011275283.1 - 0.00048 19.0 3.1 0.00048 19.0 2.1 2.1 2 1 0 2 2 2 1 Fungal specific transcription factor domain SUR7 PF06687.7 XP_011275284.1 - 1.4e-08 34.5 6.4 2.2e-08 33.9 4.5 1.3 1 0 0 1 1 1 1 SUR7/PalI family SUR7 PF06687.7 XP_011275285.1 - 4e-08 33.0 8.9 1e-07 31.7 6.1 1.7 1 1 1 2 2 2 1 SUR7/PalI family Fig1 PF12351.3 XP_011275285.1 - 0.0008 19.3 1.7 0.0008 19.3 1.2 1.8 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 Hum_adeno_E3A PF05393.6 XP_011275285.1 - 0.0078 15.8 1.4 0.015 14.9 0.1 2.1 2 0 0 2 2 2 1 Human adenovirus early E3A glycoprotein NfeD PF01957.13 XP_011275286.1 - 0.76 9.9 5.8 1.6 8.8 0.3 2.4 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding GDPD_2 PF13653.1 XP_011275287.1 - 0.077 13.2 0.6 1.3 9.2 0.2 2.6 2 0 0 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family MFS_1 PF07690.11 XP_011275288.1 - 3e-18 65.6 18.3 3e-18 65.6 12.7 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily UPF0233 PF06781.7 XP_011275288.1 - 0.46 10.1 3.6 0.55 9.8 0.0 3.0 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0233) Helicase_C PF00271.26 XP_011275289.1 - 2.9e-11 43.0 0.0 7e-11 41.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 XP_011275289.1 - 0.022 14.7 0.1 0.33 10.9 0.0 2.5 3 0 0 3 3 3 0 Helicase C-terminal domain CcdB PF01845.12 XP_011275289.1 - 0.13 12.2 0.1 33 4.4 0.0 2.9 3 0 0 3 3 3 0 CcdB protein ResIII PF04851.10 XP_011275290.1 - 3.6e-23 82.3 0.0 5e-23 81.8 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 XP_011275290.1 - 1.4e-12 47.4 0.0 1.8e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.4 XP_011275290.1 - 9.4e-06 24.8 0.1 1.3e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.1 XP_011275290.1 - 0.00015 21.4 0.1 0.025 14.1 0.0 2.1 1 1 1 2 2 2 2 AAA domain SNF2_N PF00176.18 XP_011275290.1 - 0.00022 20.1 0.0 0.00028 19.7 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.1 XP_011275290.1 - 0.00039 20.5 0.1 0.001 19.1 0.1 1.7 1 1 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.9 XP_011275290.1 - 0.035 13.8 0.0 0.049 13.3 0.0 1.2 1 0 0 1 1 1 0 Flavivirus DEAD domain PilM_2 PF11104.3 XP_011275290.1 - 0.095 11.5 0.1 0.14 10.9 0.1 1.2 1 0 0 1 1 1 0 Type IV pilus assembly protein PilM; UvrD-helicase PF00580.16 XP_011275290.1 - 0.11 11.7 0.7 0.42 9.8 0.5 1.8 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_10 PF12846.2 XP_011275290.1 - 0.16 11.4 0.7 2.7 7.3 0.1 2.6 1 1 0 1 1 1 0 AAA-like domain DUF2554 PF10829.3 XP_011275291.1 - 0.068 13.2 0.0 0.98 9.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2554) DUF4345 PF14248.1 XP_011275291.1 - 0.095 12.1 0.5 0.23 10.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4345) MFS_1 PF07690.11 XP_011275292.1 - 3.6e-11 42.3 15.0 3.2e-09 35.9 3.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily ER_lumen_recept PF00810.13 XP_011275292.1 - 0.028 14.9 6.7 0.038 14.4 1.8 2.5 3 0 0 3 3 3 0 ER lumen protein retaining receptor MFS_1 PF07690.11 XP_011275293.1 - 2.9e-11 42.6 1.5 3.7e-11 42.3 1.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily zf-RING_2 PF13639.1 XP_011275294.1 - 1e-07 31.6 6.7 1.8e-07 30.8 4.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 XP_011275294.1 - 1.6e-05 24.4 4.5 3.6e-05 23.4 3.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 XP_011275294.1 - 5.8e-05 23.0 5.2 0.00012 22.0 3.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 XP_011275294.1 - 0.0029 17.2 5.4 0.0071 15.9 3.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 XP_011275294.1 - 0.0029 17.2 2.8 0.0058 16.2 1.9 1.5 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.1 XP_011275294.1 - 0.0041 16.8 2.4 0.0043 16.7 0.2 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 1 zf-RING_UBOX PF13445.1 XP_011275294.1 - 0.0043 16.7 3.3 0.0089 15.7 2.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger FANCL_C PF11793.3 XP_011275294.1 - 0.0058 16.5 4.3 0.011 15.6 2.5 1.8 1 1 0 1 1 1 1 FANCL C-terminal domain zf-rbx1 PF12678.2 XP_011275294.1 - 0.63 10.1 6.0 1.5 9.0 4.1 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger adh_short PF00106.20 XP_011275295.1 - 1.7e-16 60.5 0.1 2.7e-16 59.9 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 XP_011275295.1 - 4.8e-10 39.6 0.2 5.4e-10 39.4 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 XP_011275295.1 - 1e-09 38.3 0.2 1.6e-09 37.7 0.1 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 XP_011275295.1 - 4.2e-05 23.0 0.4 0.00011 21.7 0.2 1.7 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 XP_011275295.1 - 0.00098 19.1 0.2 0.0013 18.7 0.1 1.4 1 1 0 1 1 1 1 NADH(P)-binding DUF4614 PF15391.1 XP_011275295.1 - 0.072 12.8 0.9 0.14 11.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) adh_short PF00106.20 XP_011275296.1 - 1.1e-14 54.6 0.0 1.4e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 XP_011275296.1 - 4.3e-10 39.5 0.0 5.8e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 XP_011275296.1 - 5.6e-08 32.8 0.0 6.6e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 XP_011275296.1 - 0.0086 15.5 0.3 0.03 13.7 0.2 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 XP_011275296.1 - 0.05 13.5 0.0 0.075 13.0 0.0 1.3 1 1 0 1 1 1 0 NADH(P)-binding adh_short PF00106.20 XP_011275297.1 - 8.7e-12 45.2 0.0 1.3e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 XP_011275297.1 - 1.8e-06 27.7 0.0 2.4e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 XP_011275297.1 - 0.0096 15.9 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 XP_011275297.1 - 0.0098 15.6 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF2088 PF09861.4 XP_011275297.1 - 0.026 13.5 0.1 0.043 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2088) adh_short PF00106.20 XP_011275298.1 - 1.4e-13 51.1 0.0 2e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 XP_011275298.1 - 7.9e-08 32.3 0.2 9.5e-08 32.0 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 XP_011275298.1 - 1.8e-07 31.0 0.0 2.6e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF2088 PF09861.4 XP_011275298.1 - 0.093 11.7 0.3 0.18 10.7 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF2088) ArfGap PF01412.13 XP_011275299.1 - 2.8e-35 120.5 0.3 2.8e-35 120.5 0.2 2.5 2 1 0 2 2 2 1 Putative GTPase activating protein for Arf FAD_binding_3 PF01494.14 XP_011275300.1 - 2.8e-21 75.9 0.0 6.3e-21 74.8 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 XP_011275300.1 - 2.5e-09 37.4 0.4 1.2e-05 25.5 0.0 3.1 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 XP_011275300.1 - 1.6e-06 28.0 0.0 4.6e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 XP_011275300.1 - 8.9e-06 24.8 0.0 2.8e-05 23.1 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase SE PF08491.5 XP_011275300.1 - 3.7e-05 22.6 0.0 0.00062 18.6 0.0 2.2 2 0 0 2 2 2 1 Squalene epoxidase GIDA PF01134.17 XP_011275300.1 - 0.00031 19.7 0.0 0.00044 19.2 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A 3HCDH_N PF02737.13 XP_011275300.1 - 0.00059 19.5 0.0 0.0011 18.6 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.9 XP_011275300.1 - 0.0012 17.5 0.1 0.59 8.6 0.0 2.7 3 0 0 3 3 3 2 Tryptophan halogenase FAD_binding_2 PF00890.19 XP_011275300.1 - 0.0025 16.7 0.0 0.0077 15.1 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain ApbA PF02558.11 XP_011275300.1 - 0.0053 16.1 0.0 0.011 15.1 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.9 XP_011275300.1 - 0.0084 16.0 0.1 0.049 13.4 0.1 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 XP_011275300.1 - 0.015 13.8 0.0 0.41 9.0 0.0 2.3 2 0 0 2 2 2 0 HI0933-like protein UDPG_MGDP_dh_N PF03721.9 XP_011275300.1 - 0.022 14.1 0.0 0.04 13.2 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.16 XP_011275300.1 - 0.12 11.9 0.1 8.8 5.8 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 XP_011275300.1 - 0.13 11.3 0.2 0.24 10.4 0.1 1.4 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.2 XP_011275300.1 - 0.14 11.2 0.2 0.72 8.8 0.2 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 XP_011275300.1 - 0.15 12.0 0.0 0.45 10.5 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Raptor_N PF14538.1 XP_011275301.1 - 2.2e-67 225.6 0.1 4.9e-67 224.5 0.0 1.6 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 XP_011275301.1 - 2.6e-09 36.6 13.2 0.094 12.6 0.0 7.4 8 0 0 8 8 8 4 WD domain, G-beta repeat HEAT PF02985.17 XP_011275301.1 - 9.3e-06 25.3 2.2 0.26 11.4 0.0 5.5 5 0 0 5 5 5 1 HEAT repeat Cnd1 PF12717.2 XP_011275301.1 - 0.00021 21.1 2.5 0.11 12.3 0.0 2.7 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 XP_011275301.1 - 0.00025 21.2 0.0 0.0029 17.8 0.0 2.7 1 1 0 1 1 1 1 HEAT repeats DUF2470 PF10615.4 XP_011275303.1 - 2.2e-18 66.2 0.4 3.7e-18 65.5 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) DUF4306 PF14154.1 XP_011275303.1 - 0.035 14.0 2.0 0.12 12.4 1.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4306) Bac_luciferase PF00296.15 XP_011275304.1 - 3.2e-51 174.2 0.0 4.6e-51 173.7 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase OPT PF03169.10 XP_011275305.1 - 5.2e-164 547.1 42.0 6e-164 546.9 29.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Cyclin_N PF00134.18 XP_011275307.1 - 6.8e-44 148.5 0.6 3.5e-43 146.1 0.1 2.4 3 0 0 3 3 3 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 XP_011275307.1 - 3.5e-32 110.8 2.0 2.3e-31 108.1 0.0 2.9 3 1 0 3 3 3 1 Cyclin, C-terminal domain Cyclin_N PF00134.18 XP_011275308.1 - 7.8e-38 128.9 0.2 2e-36 124.3 0.2 2.4 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 XP_011275308.1 - 1.6e-28 98.9 0.1 7.1e-28 96.9 0.0 2.2 3 0 0 3 3 3 1 Cyclin, C-terminal domain NIR_SIR PF01077.17 XP_011275309.1 - 1.3e-30 105.8 0.1 6.7e-30 103.5 0.0 2.1 2 0 0 2 2 2 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox_2 PF07992.9 XP_011275309.1 - 5.6e-21 75.3 0.0 9.9e-21 74.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.1 XP_011275309.1 - 2.2e-18 65.8 0.0 4.4e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Pyr_redox PF00070.22 XP_011275309.1 - 3.1e-14 53.1 1.9 5.6e-14 52.3 0.3 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.10 XP_011275309.1 - 4.6e-12 45.7 0.4 7.6e-10 38.6 0.2 2.5 2 0 0 2 2 2 1 BFD-like [2Fe-2S] binding domain Rieske PF00355.21 XP_011275309.1 - 7.5e-11 41.4 0.0 1.5e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain NIR_SIR_ferr PF03460.12 XP_011275309.1 - 6e-10 38.6 0.0 1.1e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Pyr_redox_3 PF13738.1 XP_011275309.1 - 2.9e-05 24.2 0.0 0.0031 17.5 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 XP_011275309.1 - 0.048 13.4 0.1 9.3 6.0 0.0 3.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 XP_011275309.1 - 0.17 10.6 0.1 1.1 8.0 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain FAP PF07174.6 XP_011275309.1 - 0.25 10.6 0.0 0.39 9.9 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Mo-co_dimer PF03404.11 XP_011275310.1 - 1.2e-46 157.6 0.1 3.2e-46 156.1 0.1 1.8 2 0 0 2 2 2 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.14 XP_011275310.1 - 7e-42 142.7 0.0 1.2e-41 141.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.19 XP_011275310.1 - 3.3e-29 100.9 0.0 6.4e-29 100.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 XP_011275310.1 - 9.7e-26 90.4 0.1 2.8e-25 88.9 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.23 XP_011275310.1 - 4.1e-23 80.9 0.0 8.2e-23 79.9 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.7 XP_011275310.1 - 2.3e-08 34.1 0.0 0.00032 20.6 0.0 2.4 1 1 1 2 2 2 2 Ferric reductase NAD binding domain TP_methylase PF00590.15 XP_011275311.1 - 5.5e-40 137.3 0.0 7.9e-40 136.7 0.0 1.2 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.1 XP_011275311.1 - 0.0018 18.5 0.0 0.0039 17.4 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 XP_011275311.1 - 0.0067 15.7 0.1 0.36 10.1 0.0 3.0 2 1 0 2 2 2 1 Sirohaem biosynthesis protein C-terminal XPG_N PF00752.12 XP_011275311.1 - 0.073 13.3 0.1 0.24 11.7 0.0 1.9 2 0 0 2 2 2 0 XPG N-terminal domain MFS_1 PF07690.11 XP_011275312.1 - 1e-23 83.6 13.4 1.4e-23 83.2 9.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily AA_permease_2 PF13520.1 XP_011275313.1 - 5.7e-92 308.4 44.8 7.1e-92 308.1 31.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 XP_011275313.1 - 7.9e-18 64.0 36.3 1.2e-17 63.4 25.1 1.1 1 0 0 1 1 1 1 Amino acid permease Aldedh PF00171.17 XP_011275314.1 - 2.4e-177 589.9 3.0 2.7e-177 589.7 2.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family ESAG1 PF03238.8 XP_011275314.1 - 0.043 13.1 0.0 0.077 12.2 0.0 1.3 1 0 0 1 1 1 0 ESAG protein UBA PF00627.26 XP_011275314.1 - 0.097 12.5 0.1 0.24 11.2 0.1 1.7 1 0 0 1 1 1 0 UBA/TS-N domain Zn_ribbon_2 PF12674.2 XP_011275315.1 - 0.52 10.7 9.1 4.1 7.8 0.6 3.5 4 0 0 4 4 4 0 Putative zinc ribbon domain RIH_assoc PF08454.6 XP_011275317.1 - 0.058 13.0 1.0 0.17 11.5 0.7 1.7 1 0 0 1 1 1 0 RyR and IP3R Homology associated Methyltransf_31 PF13847.1 XP_011275320.1 - 9.5e-27 93.4 0.0 1.3e-26 93.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 XP_011275320.1 - 3e-24 85.3 0.0 6.6e-24 84.2 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 XP_011275320.1 - 6.7e-17 61.6 0.0 8e-17 61.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 XP_011275320.1 - 3.1e-16 59.2 0.0 4.5e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 XP_011275320.1 - 5.6e-16 58.8 0.0 1.2e-15 57.7 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 XP_011275320.1 - 4.1e-15 56.3 0.0 6.3e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 XP_011275320.1 - 7.7e-14 51.8 0.0 1.3e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 XP_011275320.1 - 2.7e-08 33.6 0.0 3.8e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_9 PF08003.6 XP_011275320.1 - 1.1e-07 30.9 0.0 1.3e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_4 PF02390.12 XP_011275320.1 - 2.1e-07 30.1 0.0 1.8e-06 27.1 0.0 2.1 1 1 1 2 2 2 1 Putative methyltransferase MetW PF07021.7 XP_011275320.1 - 7.2e-07 28.7 0.0 1.3e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_26 PF13659.1 XP_011275320.1 - 1.1e-06 28.6 0.0 1.9e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 XP_011275320.1 - 5.8e-05 22.5 0.0 0.00011 21.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain CheR PF01739.13 XP_011275320.1 - 0.00022 20.5 0.0 0.0021 17.3 0.0 2.1 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain Methyltransf_8 PF05148.10 XP_011275320.1 - 0.00034 20.3 0.0 0.0027 17.3 0.0 2.3 3 0 0 3 3 3 1 Hypothetical methyltransferase Methyltransf_29 PF03141.11 XP_011275320.1 - 0.0031 15.9 0.0 0.0036 15.6 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase NodS PF05401.6 XP_011275320.1 - 0.0043 16.4 0.0 0.0067 15.8 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) RrnaAD PF00398.15 XP_011275320.1 - 0.0059 15.6 0.0 0.0087 15.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase FtsJ PF01728.14 XP_011275320.1 - 0.012 15.6 0.0 0.017 15.1 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase UPF0020 PF01170.13 XP_011275320.1 - 0.014 14.9 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 PrmA PF06325.8 XP_011275320.1 - 0.02 14.0 0.0 0.03 13.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DREV PF05219.7 XP_011275320.1 - 0.023 13.5 0.0 0.048 12.5 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_32 PF13679.1 XP_011275320.1 - 0.027 14.1 0.0 0.042 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Sugar_tr PF00083.19 XP_011275321.1 - 7.5e-33 113.7 30.8 1.7e-32 112.6 21.4 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 XP_011275321.1 - 7.3e-17 61.1 52.2 1.6e-15 56.6 20.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PhoD PF09423.5 XP_011275322.1 - 2.1e-135 451.8 0.4 2.4e-135 451.6 0.2 1.0 1 0 0 1 1 1 1 PhoD-like phosphatase zf-H2C2_2 PF13465.1 XP_011275323.1 - 2.1e-14 52.9 35.5 5.6e-08 32.7 1.2 5.9 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.21 XP_011275323.1 - 3.7e-13 48.9 41.3 0.00097 19.3 1.7 5.5 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 XP_011275323.1 - 3.1e-09 36.4 35.9 0.034 14.4 0.4 5.4 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 XP_011275323.1 - 0.00031 20.7 15.8 0.0087 16.1 0.1 5.2 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding AdoMet_dc PF02675.10 XP_011275323.1 - 0.0016 18.3 0.2 0.0036 17.1 0.2 1.6 1 0 0 1 1 1 1 S-adenosylmethionine decarboxylase GCC2_GCC3 PF07699.8 XP_011275323.1 - 0.0028 17.1 1.3 0.0088 15.6 0.9 1.9 1 0 0 1 1 1 1 GCC2 and GCC3 zf-C2H2_6 PF13912.1 XP_011275323.1 - 0.016 15.0 1.4 0.016 15.0 1.0 4.9 6 0 0 6 6 6 0 C2H2-type zinc finger DUF2387 PF09526.5 XP_011275323.1 - 0.094 12.6 1.1 0.27 11.1 0.3 2.1 1 1 0 1 1 1 0 Probable metal-binding protein (DUF2387) zf-RING_3 PF14369.1 XP_011275323.1 - 0.15 12.0 6.6 2 8.4 0.0 3.0 3 0 0 3 3 3 0 zinc-finger DUF3505 PF12013.3 XP_011275323.1 - 0.33 11.2 8.4 0.042 14.0 1.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3505) zf-met PF12874.2 XP_011275323.1 - 1 9.6 10.1 6.1 7.2 0.8 3.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type FYDLN_acid PF09538.5 XP_011275323.1 - 1.7 9.2 8.9 7.6 7.1 2.3 3.1 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) PHD PF00628.24 XP_011275323.1 - 4.4 7.0 11.2 14 5.4 3.0 3.4 3 0 0 3 3 3 0 PHD-finger COesterase PF00135.23 XP_011275324.1 - 1.6e-97 327.4 0.0 2e-97 327.1 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 XP_011275324.1 - 7.4e-09 35.1 0.0 1.2e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 XP_011275324.1 - 7.8e-06 25.6 0.1 0.00015 21.3 0.1 2.7 2 1 0 2 2 2 1 alpha/beta hydrolase fold DAO PF01266.19 XP_011275325.1 - 1.5e-50 172.1 0.0 1.7e-50 171.9 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 XP_011275325.1 - 7.1e-06 26.2 0.0 0.064 13.3 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 XP_011275325.1 - 2.4e-05 24.2 0.1 8.6e-05 22.4 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 XP_011275325.1 - 0.00082 19.3 0.5 0.0091 15.8 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 XP_011275325.1 - 0.0012 17.8 0.0 0.027 13.4 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 XP_011275325.1 - 0.0027 16.8 0.0 0.0093 15.0 0.0 1.9 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 XP_011275325.1 - 0.012 14.6 0.0 0.052 12.4 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 XP_011275325.1 - 0.013 15.2 0.1 0.14 11.8 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 XP_011275325.1 - 0.19 10.5 0.0 0.34 9.6 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain OPT PF03169.10 XP_011275326.1 - 4.4e-170 567.1 45.2 5.2e-170 566.9 31.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein RPEL PF02755.10 XP_011275327.1 - 9e-08 31.2 1.6 3e-05 23.1 0.4 2.5 2 0 0 2 2 2 2 RPEL repeat F-box-like PF12937.2 XP_011275327.1 - 2.2e-07 30.4 0.3 3.9e-07 29.6 0.2 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 XP_011275327.1 - 1.8e-06 27.4 0.4 5e-06 26.0 0.3 1.7 1 0 0 1 1 1 1 F-box domain Sugar_tr PF00083.19 XP_011275328.1 - 7.2e-93 311.6 27.1 9.1e-93 311.2 18.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 XP_011275328.1 - 1.5e-21 76.5 21.7 1.5e-21 76.5 15.1 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Fungal_trans PF04082.13 XP_011275329.1 - 3.9e-11 42.3 8.7 3.9e-11 42.3 6.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 XP_011275329.1 - 8.8e-09 35.1 13.9 1.4e-08 34.4 9.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 XP_011275330.1 - 9.7e-10 37.7 10.5 1.9e-09 36.8 7.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 XP_011275330.1 - 1.3e-07 31.4 13.6 2.4e-07 30.5 9.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Nucleoplasmin PF03066.10 XP_011275331.1 - 0.0066 15.9 1.2 0.055 12.9 0.3 2.5 2 0 0 2 2 2 1 Nucleoplasmin DUF2205 PF10224.4 XP_011275332.1 - 2.9e-09 36.3 0.7 5.4e-09 35.5 0.5 1.5 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) LXG PF04740.7 XP_011275332.1 - 0.51 10.0 5.1 0.62 9.8 3.5 1.1 1 0 0 1 1 1 0 LXG domain of WXG superfamily Rrp15p PF07890.7 XP_011275333.1 - 2.2e-31 108.5 11.0 2.2e-31 108.5 7.6 2.0 2 1 0 2 2 2 1 Rrp15p CDC45 PF02724.9 XP_011275333.1 - 0.031 12.3 17.9 0.038 12.0 12.4 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF3035 PF11233.3 XP_011275333.1 - 0.15 12.1 1.3 0.27 11.2 0.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3035) Kinesin PF00225.18 XP_011275334.1 - 7.1e-105 350.3 4.4 7.1e-105 350.3 3.0 3.0 3 1 1 4 4 4 1 Kinesin motor domain PPR_2 PF13041.1 XP_011275336.1 - 0.00012 21.9 0.9 0.025 14.5 0.1 2.4 2 0 0 2 2 2 2 PPR repeat family PPR PF01535.15 XP_011275336.1 - 0.0044 16.9 0.2 1 9.4 0.0 2.6 2 0 0 2 2 2 2 PPR repeat RRM_1 PF00076.17 XP_011275337.1 - 2.4e-64 212.9 0.2 1.6e-21 75.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 XP_011275337.1 - 1.6e-45 152.9 0.0 6.4e-16 58.0 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 XP_011275337.1 - 3.4e-20 71.6 0.0 1e-07 31.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 XP_011275337.1 - 9.3e-07 28.5 0.4 0.051 13.3 0.0 3.8 3 1 0 3 3 3 2 Limkain b1 RRM_3 PF08777.6 XP_011275337.1 - 0.0032 17.3 0.1 4 7.3 0.0 2.9 3 0 0 3 3 3 2 RNA binding motif Nup35_RRM_2 PF14605.1 XP_011275337.1 - 0.0076 16.0 0.0 27 4.6 0.0 3.6 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif NIL PF09383.5 XP_011275337.1 - 0.022 14.2 0.0 6.1 6.4 0.0 3.0 3 0 0 3 3 3 0 NIL domain DUF3932 PF13068.1 XP_011275337.1 - 0.066 13.3 0.0 5.8 7.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3932) DUF1325 PF07039.6 XP_011275338.1 - 3.4e-37 126.9 0.1 9.8e-37 125.4 0.0 1.7 2 0 0 2 2 2 1 SGF29 tudor-like domain Agenet PF05641.7 XP_011275338.1 - 0.019 15.1 0.0 1.8 8.7 0.0 2.6 2 0 0 2 2 2 0 Agenet domain DUF4537 PF15057.1 XP_011275338.1 - 0.021 14.5 0.0 0.046 13.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) Zw10 PF06248.8 XP_011275338.1 - 0.07 11.2 2.4 0.093 10.8 1.7 1.1 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 Ribosomal_L27 PF01016.14 XP_011275339.1 - 3.1e-32 110.1 0.1 5.5e-32 109.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal L27 protein MoaE PF02391.12 XP_011275340.1 - 3.2e-25 88.2 0.0 4.1e-25 87.8 0.0 1.1 1 0 0 1 1 1 1 MoaE protein PLDc_2 PF13091.1 XP_011275341.1 - 3.8e-17 62.2 0.2 2.2e-08 33.8 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 XP_011275341.1 - 3.5e-06 26.6 1.9 0.027 14.2 0.0 3.3 2 1 0 2 2 2 2 Phospholipase D Active site motif CP_ATPgrasp_1 PF04174.8 XP_011275341.1 - 0.17 10.5 0.0 0.48 8.9 0.0 1.7 2 0 0 2 2 2 0 A circularly permuted ATPgrasp Rer1 PF03248.8 XP_011275342.1 - 2e-74 248.9 9.7 2.3e-74 248.8 6.7 1.0 1 0 0 1 1 1 1 Rer1 family Nucleopor_Nup85 PF07575.8 XP_011275342.1 - 0.035 12.3 0.8 0.045 11.9 0.5 1.1 1 0 0 1 1 1 0 Nup85 Nucleoporin Urm1 PF09138.6 XP_011275343.1 - 2e-25 88.7 0.0 2.2e-25 88.5 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 XP_011275343.1 - 0.00076 19.8 0.0 0.001 19.4 0.0 1.2 1 0 0 1 1 1 1 ThiS family Delta_lysin PF05372.6 XP_011275343.1 - 0.027 13.8 0.8 0.027 13.8 0.5 1.8 2 0 0 2 2 2 0 Delta lysin family Tektin PF03148.9 XP_011275344.1 - 0.032 12.7 0.1 0.041 12.4 0.1 1.2 1 0 0 1 1 1 0 Tektin family Taeniidae_ag PF05596.6 XP_011275344.1 - 0.054 13.3 0.2 0.09 12.6 0.1 1.3 1 0 0 1 1 1 0 Taeniidae antigen Proteasome PF00227.21 XP_011275345.1 - 1.8e-58 196.9 0.0 2.3e-58 196.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF3647 PF12363.3 XP_011275345.1 - 0.034 14.2 0.3 0.87 9.7 0.0 2.2 2 0 0 2 2 2 0 Phage protein TOM13 PF08219.6 XP_011275346.1 - 2.2e-25 88.2 1.4 5.2e-25 87.0 1.0 1.7 1 1 0 1 1 1 1 Outer membrane protein TOM13 Ppx-GppA PF02541.11 XP_011275347.1 - 4.2e-57 193.5 0.0 5.3e-57 193.1 0.0 1.1 1 0 0 1 1 1 1 Ppx/GppA phosphatase family GDA1_CD39 PF01150.12 XP_011275347.1 - 0.097 11.1 0.0 0.22 9.9 0.0 1.5 1 0 0 1 1 1 0 GDA1/CD39 (nucleoside phosphatase) family Hexokinase_2 PF03727.11 XP_011275348.1 - 2.6e-91 305.1 0.0 3.6e-91 304.6 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 XP_011275348.1 - 6.3e-83 277.1 0.0 8.3e-83 276.7 0.0 1.1 1 0 0 1 1 1 1 Hexokinase MiAMP1 PF09117.5 XP_011275348.1 - 0.15 12.5 0.3 0.37 11.2 0.2 1.6 1 0 0 1 1 1 0 MiAMP1 RPN7 PF10602.4 XP_011275349.1 - 9.7e-53 178.1 2.0 2.3e-52 176.9 0.8 1.9 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.22 XP_011275349.1 - 1.3e-15 57.6 0.9 2.8e-15 56.5 0.1 2.0 2 0 0 2 2 2 1 PCI domain TPR_1 PF00515.23 XP_011275349.1 - 7.7e-05 22.1 0.4 0.0004 19.8 0.0 2.4 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 XP_011275349.1 - 9.9e-05 22.2 0.3 0.0028 17.5 0.0 2.7 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 XP_011275349.1 - 0.00014 21.5 0.0 0.00095 18.9 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat Lebercilin PF15619.1 XP_011275349.1 - 0.00024 20.6 0.4 0.00044 19.7 0.2 1.3 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease TPR_11 PF13414.1 XP_011275349.1 - 0.00026 20.5 0.0 0.00091 18.8 0.0 1.9 1 0 0 1 1 1 1 TPR repeat PCI_Csn8 PF10075.4 XP_011275349.1 - 0.00082 19.1 0.3 0.002 17.9 0.2 1.6 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 TPR_8 PF13181.1 XP_011275349.1 - 0.0032 17.1 0.8 0.017 14.8 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF2989 PF11207.3 XP_011275349.1 - 0.0054 16.2 1.6 0.013 14.9 0.0 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF2989) TPR_7 PF13176.1 XP_011275349.1 - 0.017 14.9 0.0 0.14 12.0 0.0 2.6 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF357 PF04010.8 XP_011275349.1 - 0.025 14.2 0.4 0.064 12.9 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF357) TPR_14 PF13428.1 XP_011275349.1 - 0.05 14.2 0.0 0.21 12.3 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF706 PF05153.10 XP_011275349.1 - 0.052 12.8 0.6 0.23 10.7 0.2 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF706) TPR_19 PF14559.1 XP_011275349.1 - 0.062 13.6 0.0 0.24 11.7 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF3782 PF12644.2 XP_011275349.1 - 0.095 12.5 0.6 0.23 11.2 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3782) TPR_6 PF13174.1 XP_011275349.1 - 0.12 12.9 0.5 0.76 10.3 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat EMP24_GP25L PF01105.19 XP_011275350.1 - 2.1e-36 125.3 1.7 2.5e-36 125.0 1.2 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Ribonucleas_3_3 PF14622.1 XP_011275350.1 - 0.083 12.8 0.1 0.21 11.5 0.1 1.6 1 1 0 1 1 1 0 Ribonuclease-III-like TP6A_N PF04406.9 XP_011275351.1 - 1.1e-16 60.2 0.4 2.5e-16 59.0 0.2 1.5 1 0 0 1 1 1 1 Type IIB DNA topoisomerase DUF2220 PF09983.4 XP_011275351.1 - 7.7e-05 21.9 0.0 0.00015 20.9 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria C-term(DUF2220) DUF2399 PF09664.5 XP_011275351.1 - 0.0005 19.9 0.0 0.0026 17.6 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2399) TauD PF02668.11 XP_011275352.1 - 6.4e-54 183.3 0.0 8.8e-54 182.8 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family GIT_SHD PF08518.6 XP_011275353.1 - 1.3e-21 75.6 6.0 2.4e-13 49.1 0.5 2.7 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT zf-C2H2 PF00096.21 XP_011275354.1 - 9e-08 32.0 16.8 0.0004 20.5 2.6 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 XP_011275354.1 - 9.8e-07 28.6 11.8 0.0046 17.1 3.0 3.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 XP_011275354.1 - 3.1e-06 27.2 9.6 2.6e-05 24.2 3.2 3.2 2 0 0 2 2 2 1 Zinc-finger double domain zf-met PF12874.2 XP_011275354.1 - 0.00081 19.5 3.4 1.2 9.4 0.7 3.1 2 0 0 2 2 2 2 Zinc-finger of C2H2 type Rad9_Rad53_bind PF08605.5 XP_011275355.1 - 6.3e-29 100.4 1.8 7.3e-28 96.9 0.1 2.4 2 0 0 2 2 2 1 Fungal Rad9-like Rad53-binding BRCT PF00533.21 XP_011275355.1 - 8.4e-06 25.8 8.4 3e-05 24.0 0.0 3.7 2 2 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Septin PF00735.13 XP_011275357.1 - 1.3e-85 286.8 3.4 2.6e-85 285.8 2.3 1.5 1 1 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 XP_011275357.1 - 0.00049 20.0 0.3 0.0014 18.5 0.2 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase IIGP PF05049.8 XP_011275357.1 - 0.0048 15.7 0.0 0.0048 15.7 0.0 2.2 3 0 0 3 3 3 1 Interferon-inducible GTPase (IIGP) Miro PF08477.8 XP_011275357.1 - 0.0063 17.0 0.3 0.021 15.3 0.1 2.0 2 0 0 2 2 2 1 Miro-like protein AAA_29 PF13555.1 XP_011275357.1 - 0.0069 15.8 0.3 0.021 14.3 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 XP_011275357.1 - 0.0075 15.4 0.0 0.015 14.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 XP_011275357.1 - 0.0084 16.2 0.0 0.025 14.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 XP_011275357.1 - 0.01 15.3 0.0 0.023 14.1 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Sigma54_activ_2 PF14532.1 XP_011275357.1 - 0.017 15.1 0.0 0.061 13.3 0.0 1.9 1 0 0 1 1 1 0 Sigma-54 interaction domain SPT2 PF08243.6 XP_011275357.1 - 0.019 15.2 2.8 4.6 7.5 0.0 2.8 3 0 0 3 3 3 0 SPT2 chromatin protein ABC_tran PF00005.22 XP_011275357.1 - 0.037 14.3 0.6 0.037 14.3 0.4 2.6 1 1 0 2 2 2 0 ABC transporter RNA_helicase PF00910.17 XP_011275357.1 - 0.044 13.9 0.3 0.28 11.3 0.0 2.5 3 0 0 3 3 3 0 RNA helicase Dynamin_N PF00350.18 XP_011275357.1 - 0.047 13.5 0.1 0.047 13.5 0.1 2.5 2 2 1 3 3 3 0 Dynamin family AAA_16 PF13191.1 XP_011275357.1 - 0.052 13.5 0.2 0.21 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain MobB PF03205.9 XP_011275357.1 - 0.054 13.2 0.1 0.27 10.9 0.1 2.2 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 XP_011275357.1 - 0.077 11.8 0.1 0.13 11.1 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.7 XP_011275357.1 - 0.088 12.4 0.5 0.46 10.1 0.0 2.2 2 1 0 2 2 2 0 NACHT domain DUF2175 PF09943.4 XP_011275357.1 - 0.13 12.2 6.4 0.099 12.7 1.8 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) MutS_V PF00488.16 XP_011275357.1 - 0.14 11.5 0.5 1.3 8.3 0.0 2.4 3 0 0 3 3 3 0 MutS domain V Cyclin_N PF00134.18 XP_011275358.1 - 5.3e-11 42.1 0.2 1.3e-10 40.9 0.2 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.14 XP_011275358.1 - 0.0005 19.8 0.6 0.0015 18.3 0.4 1.8 1 0 0 1 1 1 1 Transcription factor TFIIB repeat Zn_clus PF00172.13 XP_011275359.1 - 2.2e-07 30.6 15.6 3.4e-07 30.0 10.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_5 PF00266.14 XP_011275360.1 - 4.3e-28 98.1 0.0 5.3e-28 97.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 XP_011275360.1 - 2.4e-05 23.4 0.0 3.8e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II CDC48_2 PF02933.12 XP_011275360.1 - 0.027 14.1 0.0 0.075 12.6 0.0 1.7 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 Pex24p PF06398.6 XP_011275361.1 - 0.0015 17.3 0.2 0.002 16.9 0.1 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin MRVI1 PF05781.7 XP_011275361.1 - 0.035 12.4 0.1 0.062 11.6 0.1 1.3 1 0 0 1 1 1 0 MRVI1 protein DUF2098 PF09871.4 XP_011275361.1 - 0.095 12.6 0.6 0.13 12.1 0.5 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2098) DUF788 PF05620.6 XP_011275361.1 - 0.69 9.7 2.8 0.36 10.6 0.4 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF788) Selenoprotein_S PF06936.6 XP_011275361.1 - 2.7 7.4 4.9 2.6 7.5 0.2 2.0 1 1 1 2 2 2 0 Selenoprotein S (SelS) Nucleoside_tran PF01733.13 XP_011275363.1 - 0.002 17.3 0.6 0.0028 16.8 0.4 1.1 1 0 0 1 1 1 1 Nucleoside transporter PAS PF00989.19 XP_011275363.1 - 0.0088 15.8 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 PAS fold Vmethyltransf_C PF08456.5 XP_011275363.1 - 0.06 12.7 0.3 0.089 12.1 0.2 1.2 1 0 0 1 1 1 0 Viral methyltransferase C-terminal DUF4199 PF13858.1 XP_011275363.1 - 0.15 12.0 4.5 0.063 13.2 0.5 2.0 1 1 2 3 3 3 0 Protein of unknown function (DUF4199) GspL_C PF12693.2 XP_011275363.1 - 0.32 10.7 1.9 0.44 10.2 0.3 1.8 1 1 1 2 2 2 0 GspL periplasmic domain Patched PF02460.13 XP_011275364.1 - 0.036 11.9 1.2 0.041 11.8 0.9 1.1 1 0 0 1 1 1 0 Patched family 5_3_exonuc_N PF02739.11 XP_011275364.1 - 0.049 12.9 0.0 0.089 12.1 0.0 1.3 1 0 0 1 1 1 0 5'-3' exonuclease, N-terminal resolvase-like domain SPX PF03105.14 XP_011275365.1 - 4.6e-48 164.3 6.5 6.6e-48 163.8 4.5 1.2 1 0 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 XP_011275365.1 - 6.3e-27 94.5 43.0 8.3e-27 94.1 29.8 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 XP_011275365.1 - 1.8e-15 56.3 42.9 2.3e-15 56.0 13.8 2.1 1 1 1 2 2 2 2 Citrate transporter Pr_beta_C PF12465.3 XP_011275365.1 - 0.034 13.3 0.0 0.071 12.3 0.0 1.5 1 0 0 1 1 1 0 Proteasome beta subunits C terminal PRK PF00485.13 XP_011275366.1 - 4.6e-56 189.4 0.0 7e-56 188.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.1 XP_011275366.1 - 1.3e-41 142.0 0.0 2.1e-41 141.4 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_17 PF13207.1 XP_011275366.1 - 2e-08 35.0 0.2 9.7e-08 32.8 0.0 2.3 2 2 0 2 2 2 1 AAA domain AAA_18 PF13238.1 XP_011275366.1 - 8.2e-07 29.3 0.0 2.1e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 XP_011275366.1 - 0.00017 20.7 0.0 0.00031 19.9 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin KAP_NTPase PF07693.9 XP_011275366.1 - 0.00037 19.5 0.0 0.0006 18.9 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain AAA_33 PF13671.1 XP_011275366.1 - 0.00071 19.4 0.0 0.0018 18.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain CPT PF07931.7 XP_011275366.1 - 0.00084 18.9 0.0 0.0016 18.0 0.0 1.5 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein MobB PF03205.9 XP_011275366.1 - 0.0079 15.9 0.1 0.043 13.5 0.0 2.2 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 XP_011275366.1 - 0.012 15.8 0.0 0.089 12.9 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 XP_011275366.1 - 0.02 14.8 0.0 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.1 XP_011275366.1 - 0.078 12.5 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 XP_011275366.1 - 0.079 11.8 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.1 XP_011275366.1 - 0.079 13.1 0.1 0.23 11.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.15 XP_011275366.1 - 0.093 12.3 0.0 3.1 7.4 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase ABC_tran PF00005.22 XP_011275367.1 - 3.2e-52 176.4 1.7 1.5e-25 90.1 0.0 3.0 3 0 0 3 3 2 2 ABC transporter ABC2_membrane PF01061.19 XP_011275367.1 - 8.9e-34 116.4 43.1 6.5e-23 80.9 16.1 2.8 4 0 0 4 4 2 2 ABC-2 type transporter SMC_N PF02463.14 XP_011275367.1 - 3.6e-13 49.2 3.5 6.6e-06 25.5 0.2 3.3 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 XP_011275367.1 - 1.3e-12 48.3 36.7 1.5e-07 31.6 3.3 5.9 5 2 0 5 5 3 2 AAA domain DUF258 PF03193.11 XP_011275367.1 - 1.5e-10 40.4 0.6 0.00057 19.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_15 PF13175.1 XP_011275367.1 - 1e-08 34.7 24.3 0.012 14.7 0.6 5.5 4 1 1 5 5 5 4 AAA ATPase domain AAA_29 PF13555.1 XP_011275367.1 - 1.8e-07 30.5 2.1 0.014 14.8 0.1 3.4 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_25 PF13481.1 XP_011275367.1 - 1.8e-07 30.7 0.0 0.013 14.9 0.0 4.2 4 0 0 4 4 4 1 AAA domain AAA_16 PF13191.1 XP_011275367.1 - 2.7e-07 30.7 0.0 0.019 14.9 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 XP_011275367.1 - 4.7e-07 30.0 0.8 0.047 13.8 0.1 3.2 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 XP_011275367.1 - 5.6e-07 30.3 0.0 0.032 15.0 0.0 3.0 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 XP_011275367.1 - 3.4e-06 27.0 0.1 0.021 14.7 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 XP_011275367.1 - 5.3e-06 26.0 0.1 0.00041 19.8 0.0 2.6 3 0 0 3 3 2 1 FtsK/SpoIIIE family NACHT PF05729.7 XP_011275367.1 - 8e-06 25.6 0.0 0.041 13.5 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_18 PF13238.1 XP_011275367.1 - 9.4e-06 25.9 0.9 0.048 13.9 0.0 3.3 3 0 0 3 3 2 2 AAA domain AAA_23 PF13476.1 XP_011275367.1 - 1.1e-05 25.8 0.1 1.1e-05 25.8 0.1 4.1 3 1 0 3 3 2 1 AAA domain cobW PF02492.14 XP_011275367.1 - 2.3e-05 23.9 1.1 0.13 11.6 0.0 2.5 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.1 XP_011275367.1 - 3.3e-05 23.8 0.6 0.052 13.4 0.1 2.6 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 XP_011275367.1 - 5.6e-05 22.9 0.0 0.17 11.5 0.0 2.7 2 0 0 2 2 2 2 Archaeal ATPase AAA_14 PF13173.1 XP_011275367.1 - 6.1e-05 22.9 0.1 0.28 11.0 0.0 3.4 3 0 0 3 3 2 2 AAA domain T2SE PF00437.15 XP_011275367.1 - 6.3e-05 22.0 0.7 0.19 10.5 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_33 PF13671.1 XP_011275367.1 - 0.00019 21.3 0.1 0.68 9.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.1 XP_011275367.1 - 0.00028 20.5 1.2 0.35 10.4 0.0 2.9 3 0 0 3 3 2 2 AAA domain Miro PF08477.8 XP_011275367.1 - 0.00029 21.3 0.1 1.6 9.2 0.0 3.3 4 0 0 4 4 2 1 Miro-like protein AAA_10 PF12846.2 XP_011275367.1 - 0.00035 20.0 4.7 0.15 11.5 0.3 2.5 2 0 0 2 2 2 2 AAA-like domain Septin PF00735.13 XP_011275367.1 - 0.00042 19.4 0.1 0.18 10.8 0.0 2.5 2 0 0 2 2 2 1 Septin SbcCD_C PF13558.1 XP_011275367.1 - 0.00044 20.1 0.2 2.4 8.1 0.1 3.3 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit NTPase_1 PF03266.10 XP_011275367.1 - 0.0014 18.3 2.3 0.72 9.5 0.1 3.7 4 0 0 4 4 4 1 NTPase AAA_19 PF13245.1 XP_011275367.1 - 0.0015 18.2 0.0 1 9.1 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain RNA_helicase PF00910.17 XP_011275367.1 - 0.0015 18.6 0.0 2.6 8.2 0.0 3.3 3 0 0 3 3 2 1 RNA helicase NB-ARC PF00931.17 XP_011275367.1 - 0.0017 17.3 1.1 1.1 8.0 0.0 2.8 2 2 0 2 2 2 2 NB-ARC domain SRPRB PF09439.5 XP_011275367.1 - 0.002 17.3 0.5 0.87 8.7 0.0 2.4 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_5 PF07728.9 XP_011275367.1 - 0.0028 17.3 0.1 4.4 7.0 0.0 3.1 4 0 0 4 4 2 0 AAA domain (dynein-related subfamily) MobB PF03205.9 XP_011275367.1 - 0.0035 17.0 1.2 2.8 7.6 0.2 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B ATP-synt_ab PF00006.20 XP_011275367.1 - 0.006 16.1 0.0 0.97 8.8 0.0 3.0 3 0 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_30 PF13604.1 XP_011275367.1 - 0.0065 16.0 0.4 3.6 7.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 XP_011275367.1 - 0.0067 15.9 0.7 4.6 6.7 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.12 XP_011275367.1 - 0.0093 15.5 1.5 2 7.8 0.0 2.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein PRK PF00485.13 XP_011275367.1 - 0.011 15.3 0.3 2.1 7.8 0.0 2.9 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family UPF0079 PF02367.12 XP_011275367.1 - 0.017 14.7 0.1 0.28 10.8 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 ArgK PF03308.11 XP_011275367.1 - 0.018 13.8 0.8 0.31 9.7 0.0 2.9 2 1 1 3 3 3 0 ArgK protein Ras PF00071.17 XP_011275367.1 - 0.031 13.6 0.1 3.2 7.1 0.0 2.7 2 0 0 2 2 2 0 Ras family AAA PF00004.24 XP_011275367.1 - 0.039 14.1 3.9 1.3 9.2 0.1 3.7 3 2 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.4 XP_011275367.1 - 0.039 12.5 0.7 4.3 5.8 0.0 2.7 3 0 0 3 3 3 0 Predicted ATPase of the ABC class AAA_11 PF13086.1 XP_011275367.1 - 0.047 13.2 0.3 8.1 5.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 XP_011275367.1 - 0.069 12.9 4.2 0.22 11.3 0.1 3.1 3 0 0 3 3 2 0 Domain of unknown function DUF87 Zeta_toxin PF06414.7 XP_011275367.1 - 0.1 11.6 0.1 9.6 5.2 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin IstB_IS21 PF01695.12 XP_011275367.1 - 0.18 11.1 0.2 9 5.6 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein FeoB_N PF02421.13 XP_011275367.1 - 0.36 10.1 3.1 7.1 5.8 0.1 2.8 3 0 0 3 3 3 0 Ferrous iron transport protein B Dynamin_N PF00350.18 XP_011275367.1 - 3.6 7.3 7.5 6.2 6.6 0.3 3.5 3 1 0 3 3 3 0 Dynamin family Sld5 PF05916.6 XP_011275368.1 - 3.2e-13 49.9 3.2 5.1e-13 49.2 2.2 1.3 1 0 0 1 1 1 1 GINS complex protein Ras PF00071.17 XP_011275369.1 - 2.8e-29 101.5 0.0 3.7e-29 101.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 XP_011275369.1 - 1.1e-13 51.6 0.0 2.1e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 XP_011275369.1 - 2.8e-05 24.0 0.0 4.8e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 XP_011275369.1 - 5.6e-05 22.4 0.0 0.0001 21.5 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 XP_011275369.1 - 0.0013 17.9 0.0 0.0022 17.1 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 XP_011275369.1 - 0.0026 17.0 0.0 0.0037 16.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family FeoB_N PF02421.13 XP_011275369.1 - 0.022 14.0 0.0 0.07 12.4 0.0 1.8 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_14 PF13173.1 XP_011275369.1 - 0.12 12.2 0.0 0.53 10.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 XP_011275369.1 - 0.14 12.4 0.0 0.31 11.3 0.0 1.8 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 XP_011275369.1 - 0.19 11.6 0.0 0.4 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain DASH_Dad1 PF08649.5 XP_011275370.1 - 8.4e-18 63.8 0.6 1.2e-17 63.3 0.4 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad1 MKT1_C PF12246.3 XP_011275370.1 - 0.13 11.1 0.1 0.17 10.8 0.1 1.1 1 0 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication Host_attach PF10116.4 XP_011275370.1 - 0.76 10.0 3.8 1 9.6 2.6 1.4 1 1 0 1 1 1 0 Protein required for attachment to host cells CobT PF06213.7 XP_011275370.1 - 0.8 8.7 12.2 0.88 8.6 8.4 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT NOA36 PF06524.7 XP_011275370.1 - 8.1 5.6 6.6 9 5.4 4.5 1.0 1 0 0 1 1 1 0 NOA36 protein OB_NTP_bind PF07717.11 XP_011275371.1 - 9.1e-30 102.8 0.1 2.5e-29 101.4 0.1 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 XP_011275371.1 - 2.7e-23 81.9 0.3 2.7e-23 81.9 0.2 2.5 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.26 XP_011275371.1 - 4e-12 45.8 0.0 1.3e-11 44.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 XP_011275371.1 - 7.8e-08 31.9 0.4 3e-07 30.1 0.0 2.1 3 0 0 3 3 3 1 DEAD/DEAH box helicase T2SE PF00437.15 XP_011275371.1 - 0.00032 19.6 0.0 0.00076 18.4 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 XP_011275371.1 - 0.00048 20.2 2.8 0.0009 19.3 0.0 2.7 2 1 1 3 3 3 1 AAA domain KaiC PF06745.8 XP_011275371.1 - 0.025 13.7 0.0 0.12 11.4 0.0 2.2 2 0 0 2 2 2 0 KaiC AAA_30 PF13604.1 XP_011275371.1 - 0.031 13.8 0.7 0.052 13.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 XP_011275371.1 - 0.032 13.6 0.1 0.12 11.8 0.0 2.0 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_19 PF13245.1 XP_011275371.1 - 0.051 13.3 0.1 0.2 11.4 0.0 2.0 2 0 0 2 2 2 0 Part of AAA domain AAA_16 PF13191.1 XP_011275371.1 - 0.051 13.5 0.6 0.21 11.5 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AA_permease PF00324.16 XP_011275372.1 - 2.7e-143 477.7 42.3 3.1e-143 477.5 29.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 XP_011275372.1 - 8.4e-40 136.5 43.1 1.1e-39 136.1 29.8 1.0 1 0 0 1 1 1 1 Amino acid permease LRR_8 PF13855.1 XP_011275373.1 - 1.8e-07 30.8 12.5 4.7e-06 26.2 0.8 2.7 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.2 XP_011275373.1 - 6.9e-05 22.3 12.1 0.00086 18.8 4.7 4.0 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 XP_011275373.1 - 0.0058 16.4 2.8 23 5.5 0.0 4.7 3 1 1 4 4 4 1 Leucine Rich Repeat DUF3812 PF12757.2 XP_011275373.1 - 0.037 14.0 0.8 0.1 12.5 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3812) LRR_7 PF13504.1 XP_011275373.1 - 0.2 11.9 1.6 10 6.8 0.1 3.9 4 0 0 4 4 4 0 Leucine rich repeat PFK PF00365.15 XP_011275374.1 - 4.2e-170 564.0 4.3 2.3e-127 423.7 1.5 2.1 2 0 0 2 2 2 2 Phosphofructokinase Glyoxalase_2 PF12681.2 XP_011275374.1 - 0.00015 22.3 0.0 0.00035 21.1 0.0 1.6 1 0 0 1 1 1 1 Glyoxalase-like domain HHH_3 PF12836.2 XP_011275376.1 - 0.0057 16.5 0.0 0.012 15.5 0.0 1.5 2 0 0 2 2 2 1 Helix-hairpin-helix motif PTS_2-RNA PF01885.11 XP_011275377.1 - 1e-59 200.9 0.4 1.2e-59 200.7 0.3 1.0 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family La PF05383.12 XP_011275377.1 - 0.014 15.1 0.3 0.05 13.3 0.0 2.1 2 0 0 2 2 2 0 La domain EamA PF00892.15 XP_011275379.1 - 4.3e-10 39.6 45.9 2.4e-06 27.5 13.9 3.2 3 0 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 XP_011275379.1 - 1.8e-05 24.8 32.9 0.00014 22.0 2.6 2.8 3 0 0 3 3 3 2 Multidrug resistance efflux transporter TPT PF03151.11 XP_011275379.1 - 0.006 16.2 38.0 0.018 14.6 14.8 3.7 3 2 1 4 4 4 2 Triose-phosphate Transporter family Pkinase PF00069.20 XP_011275380.1 - 2.4e-70 236.6 0.4 2.4e-70 236.6 0.3 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011275380.1 - 8.5e-56 188.8 0.6 8.5e-56 188.8 0.4 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.23 XP_011275380.1 - 1.2e-21 76.8 0.3 1.2e-21 76.8 0.2 3.1 2 0 0 2 2 2 1 P21-Rho-binding domain PH PF00169.24 XP_011275380.1 - 1.3e-07 31.7 0.3 4.4e-07 30.0 0.2 1.9 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 XP_011275380.1 - 1.6e-07 30.5 0.1 3.6e-07 29.4 0.1 1.5 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 XP_011275380.1 - 0.024 13.9 0.1 0.052 12.8 0.0 1.5 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 XP_011275380.1 - 0.11 12.1 0.8 0.32 10.7 0.0 2.1 3 0 0 3 3 3 0 Phosphotransferase enzyme family WD40 PF00400.27 XP_011275381.1 - 4.7e-42 140.3 12.6 3.7e-09 36.1 0.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 XP_011275381.1 - 4.1e-05 23.3 0.8 0.0077 15.9 0.4 2.4 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 XP_011275381.1 - 0.032 12.9 0.3 4.3 5.9 0.0 3.0 1 1 0 2 2 2 0 Nup133 N terminal like 6PF2K PF01591.13 XP_011275382.1 - 1.3e-43 148.6 4.6 1.8e-43 148.1 3.2 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase AAA_33 PF13671.1 XP_011275382.1 - 1.2e-07 31.6 0.0 2.3e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 XP_011275382.1 - 1e-06 29.5 0.9 8.7e-06 26.5 0.0 2.3 1 1 1 2 2 2 1 AAA domain KTI12 PF08433.5 XP_011275382.1 - 0.00019 20.7 0.1 0.00053 19.2 0.1 1.8 1 1 0 1 1 1 1 Chromatin associated protein KTI12 MMR_HSR1 PF01926.18 XP_011275382.1 - 0.019 14.9 0.2 0.047 13.6 0.1 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.1 XP_011275382.1 - 0.025 14.8 0.5 0.025 14.8 0.4 2.6 1 1 1 2 2 2 0 AAA domain tRNA_lig_kinase PF08303.6 XP_011275382.1 - 0.041 13.7 1.4 0.12 12.2 0.6 2.0 1 1 1 2 2 2 0 tRNA ligase kinase domain AAA_14 PF13173.1 XP_011275382.1 - 0.045 13.6 6.1 0.27 11.1 2.2 2.9 1 1 1 2 2 2 0 AAA domain Zeta_toxin PF06414.7 XP_011275382.1 - 0.066 12.3 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.1 XP_011275382.1 - 0.09 12.9 0.0 0.19 11.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain tRNA_m1G_MT PF01746.16 XP_011275384.1 - 5.3e-33 114.1 0.0 1.3e-32 112.9 0.0 1.7 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase Pneumovirus_M2 PF06436.6 XP_011275384.1 - 0.78 8.9 6.2 1.3 8.2 4.3 1.4 1 0 0 1 1 1 0 Pneumovirus matrix protein 2 (M2) Rep_fac_C PF08542.6 XP_011275385.1 - 1e-19 70.2 0.1 2.6e-19 68.9 0.1 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.24 XP_011275385.1 - 1.9e-12 47.4 0.0 3.2e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 XP_011275385.1 - 1.5e-11 44.2 0.2 1.5e-09 37.7 0.1 2.6 2 1 0 2 2 2 1 DNA polymerase III, delta subunit AAA_14 PF13173.1 XP_011275385.1 - 3.5e-08 33.4 0.0 6.3e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 XP_011275385.1 - 2.2e-07 29.9 0.1 0.00037 19.3 0.0 2.3 1 1 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 XP_011275385.1 - 2.6e-06 27.5 0.1 0.0013 18.8 0.1 2.8 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 XP_011275385.1 - 5.1e-06 26.5 0.0 0.00019 21.4 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_3 PF07726.6 XP_011275385.1 - 1.9e-05 24.2 0.0 4.1e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 XP_011275385.1 - 2.9e-05 23.2 0.0 7.5e-05 21.8 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Viral_helicase1 PF01443.13 XP_011275385.1 - 5.2e-05 22.8 0.0 7.8e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.16 XP_011275385.1 - 0.0016 17.6 0.0 0.028 13.5 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_10 PF12846.2 XP_011275385.1 - 0.0023 17.4 0.0 0.91 8.9 0.0 2.3 1 1 0 2 2 2 2 AAA-like domain FtsK_SpoIIIE PF01580.13 XP_011275385.1 - 0.0039 16.7 0.0 0.0087 15.5 0.0 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family ArgK PF03308.11 XP_011275385.1 - 0.0041 15.9 0.0 0.05 12.3 0.0 2.2 1 1 1 2 2 2 1 ArgK protein NTPase_1 PF03266.10 XP_011275385.1 - 0.0072 16.0 0.2 0.09 12.4 0.0 2.4 3 0 0 3 3 3 1 NTPase KTI12 PF08433.5 XP_011275385.1 - 0.0073 15.5 0.0 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 DNA_pol3_delta PF06144.8 XP_011275385.1 - 0.013 15.0 0.1 0.023 14.1 0.1 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_19 PF13245.1 XP_011275385.1 - 0.017 14.8 0.0 0.035 13.8 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_18 PF13238.1 XP_011275385.1 - 0.036 14.3 0.0 0.1 12.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain DEAD PF00270.24 XP_011275385.1 - 0.14 11.6 0.1 0.86 9.0 0.0 2.2 1 1 1 2 2 2 0 DEAD/DEAH box helicase Vps52 PF04129.7 XP_011275386.1 - 3.8e-111 372.1 16.3 5.1e-111 371.6 11.3 1.1 1 0 0 1 1 1 1 Vps52 / Sac2 family Nbl1_Borealin_N PF10444.4 XP_011275386.1 - 0.21 10.9 4.3 8.9 5.7 0.1 3.3 3 0 0 3 3 3 0 Nbl1 / Borealin N terminal UvrD_C PF13361.1 XP_011275387.1 - 6.7e-40 137.6 2.8 9.1e-40 137.1 0.7 2.1 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 XP_011275387.1 - 1.3e-33 116.6 7.9 9.5e-20 71.1 0.1 3.5 2 2 1 3 3 3 2 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 XP_011275387.1 - 2e-12 47.1 0.0 6.6e-12 45.4 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 XP_011275387.1 - 9.2e-11 41.3 0.0 2.4e-10 40.0 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain Viral_helicase1 PF01443.13 XP_011275387.1 - 2.7e-08 33.6 1.1 0.00034 20.2 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.1 XP_011275387.1 - 2.8e-05 23.8 0.4 2.8e-05 23.8 0.3 2.6 2 2 0 2 2 2 1 AAA domain AAA_30 PF13604.1 XP_011275387.1 - 0.00022 20.8 0.1 0.0013 18.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain Helicase_RecD PF05127.9 XP_011275387.1 - 0.016 14.8 0.0 0.05 13.2 0.0 1.9 1 0 0 1 1 1 0 Helicase PYRIN PF02758.11 XP_011275387.1 - 0.12 12.0 2.0 9.3 6.0 0.1 2.9 2 0 0 2 2 2 0 PAAD/DAPIN/Pyrin domain AAA_12 PF13087.1 XP_011275387.1 - 0.29 10.4 4.4 1 8.6 0.0 3.5 4 0 0 4 4 4 0 AAA domain RNase_P_pop3 PF08228.6 XP_011275388.1 - 1e-22 80.6 0.2 1.5e-21 76.8 0.1 2.0 1 1 0 1 1 1 1 RNase P subunit Pop3 Pkinase PF00069.20 XP_011275389.1 - 4.3e-16 58.8 0.0 6.6e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011275389.1 - 6.6e-11 41.7 0.0 9.9e-11 41.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Collagen PF01391.13 XP_011275390.1 - 1.8 8.1 9.2 7 6.2 6.4 2.0 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) Macoilin PF09726.4 XP_011275390.1 - 9.5 4.3 23.7 0.15 10.3 11.5 1.5 2 0 0 2 2 2 0 Transmembrane protein Glyco_hydro_15 PF00723.16 XP_011275391.1 - 1.2e-56 192.2 0.0 2.1e-56 191.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 PRONE PF03759.8 XP_011275391.1 - 0.0064 15.0 0.0 0.0097 14.4 0.0 1.2 1 0 0 1 1 1 1 PRONE (Plant-specific Rop nucleotide exchanger) Ribosomal_S9 PF00380.14 XP_011275392.1 - 4.5e-37 126.9 0.1 8.6e-37 126.0 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S9/S16 CENP-S PF15630.1 XP_011275393.1 - 7.2e-14 51.7 0.8 5.1e-13 49.0 0.6 2.2 1 1 0 1 1 1 1 Kinetochore component CENP-S Histone PF00125.19 XP_011275393.1 - 0.0016 18.5 0.2 0.0025 17.8 0.1 1.5 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 XP_011275393.1 - 0.039 13.7 0.2 0.06 13.1 0.1 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit DUF4611 PF15387.1 XP_011275393.1 - 0.09 12.9 3.2 0.24 11.5 2.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) CBFD_NFYB_HMF PF00808.18 XP_011275393.1 - 0.11 12.5 0.4 0.33 11.0 0.1 2.1 2 1 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PBP1_TM PF14812.1 XP_011275393.1 - 0.6 10.4 5.5 1.2 9.4 3.8 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3337 PF11816.3 XP_011275394.1 - 9.6e-60 202.7 7.0 5.8e-56 190.2 6.4 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF3337) WD40 PF00400.27 XP_011275394.1 - 2.1e-18 65.4 9.0 1.8e-05 24.3 0.0 6.2 5 1 1 6 6 6 4 WD domain, G-beta repeat RNA_pol_Rpb5_C PF01191.14 XP_011275395.1 - 7.6e-35 118.3 0.5 1.5e-34 117.4 0.3 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 XP_011275395.1 - 2.5e-31 107.9 0.1 3.8e-31 107.3 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain AAA_3 PF07726.6 XP_011275395.1 - 0.015 14.9 0.0 0.022 14.3 0.0 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sof1 PF04158.9 XP_011275395.1 - 0.039 13.9 0.1 0.061 13.3 0.0 1.3 1 0 0 1 1 1 0 Sof1-like domain Mrr_cat PF04471.7 XP_011275395.1 - 0.096 12.4 0.0 1.9 8.3 0.0 2.1 2 0 0 2 2 2 0 Restriction endonuclease Oxidored_FMN PF00724.15 XP_011275396.1 - 2.6e-93 312.7 0.0 3e-93 312.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Sulf_coat_C PF12193.3 XP_011275396.1 - 0.047 13.5 0.0 0.094 12.5 0.0 1.4 1 0 0 1 1 1 0 Sulfolobus virus coat protein C terminal Oxidored_FMN PF00724.15 XP_011275397.1 - 4e-100 335.1 0.0 4.5e-100 334.9 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family PUF PF00806.14 XP_011275397.1 - 0.12 11.9 0.1 8.7 6.0 0.0 2.6 2 0 0 2 2 2 0 Pumilio-family RNA binding repeat MFS_1 PF07690.11 XP_011275398.1 - 2.3e-16 59.4 31.2 2.3e-16 59.4 21.6 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 XP_011275398.1 - 2.2e-08 33.7 13.3 2.3e-08 33.6 6.0 2.8 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 RibD_C PF01872.12 XP_011275399.1 - 9.5e-40 136.3 0.0 1.1e-39 136.1 0.0 1.0 1 0 0 1 1 1 1 RibD C-terminal domain Prp19_bind PF06991.6 XP_011275400.1 - 1.7e-21 76.7 41.8 1.7e-21 76.7 29.0 2.1 1 1 1 2 2 2 1 Splicing factor, Prp19-binding domain SOBP PF15279.1 XP_011275400.1 - 2.4 8.4 10.1 3.2 8.0 7.0 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein Peptidase_S10 PF00450.17 XP_011275401.1 - 5.8e-126 420.9 0.3 7.7e-126 420.6 0.2 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 XP_011275401.1 - 0.0036 17.1 0.0 0.02 14.7 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 XP_011275401.1 - 0.098 12.4 0.0 0.66 9.7 0.0 2.1 1 1 0 1 1 1 0 Alpha/beta hydrolase family SID PF11778.3 XP_011275401.1 - 0.13 12.1 0.4 3.4 7.5 0.0 2.6 2 0 0 2 2 2 0 Septation initiation Peptidase_S8 PF00082.17 XP_011275402.1 - 7.7e-41 140.0 10.1 1.1e-40 139.5 7.0 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 XP_011275402.1 - 0.009 16.5 0.6 0.029 14.9 0.1 2.2 2 0 0 2 2 2 1 Peptidase inhibitor I9 TPP_enzyme_N PF02776.13 XP_011275402.1 - 0.11 11.9 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Peptidase_S8 PF00082.17 XP_011275403.1 - 2.7e-38 131.7 4.8 3.5e-38 131.3 3.3 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 XP_011275403.1 - 0.0041 17.6 0.3 0.034 14.6 0.0 2.4 2 0 0 2 2 2 1 Peptidase inhibitor I9 RVP PF00077.15 XP_011275403.1 - 0.051 13.4 0.9 0.087 12.7 0.1 1.8 2 0 0 2 2 2 0 Retroviral aspartyl protease Peptidase_S8 PF00082.17 XP_011275404.1 - 2.8e-38 131.6 9.0 3.8e-38 131.2 6.3 1.1 1 0 0 1 1 1 1 Subtilase family Peptidase_S8 PF00082.17 XP_011275405.1 - 3.7e-42 144.4 10.7 5e-42 143.9 7.4 1.2 1 0 0 1 1 1 1 Subtilase family DUF2167 PF09935.4 XP_011275405.1 - 0.016 14.0 0.2 0.031 13.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2167) Peptidase_S8 PF00082.17 XP_011275406.1 - 9.4e-47 159.4 12.0 1.4e-46 158.9 8.3 1.2 1 0 0 1 1 1 1 Subtilase family Peptidase_S8 PF00082.17 XP_011275407.1 - 1.3e-43 149.2 6.6 1.7e-43 148.8 4.5 1.1 1 0 0 1 1 1 1 Subtilase family Peptidase_S8 PF00082.17 XP_011275408.1 - 5.3e-39 134.0 10.7 5.3e-39 134.0 7.4 2.2 2 0 0 2 2 2 1 Subtilase family Inhibitor_I9 PF05922.11 XP_011275408.1 - 0.00078 19.9 0.9 0.022 15.2 0.0 2.8 3 0 0 3 3 3 1 Peptidase inhibitor I9 DUF836 PF05768.9 XP_011275408.1 - 0.0092 16.2 0.1 6.7 7.0 0.0 2.5 2 0 0 2 2 2 2 Glutaredoxin-like domain (DUF836) Peptidase_S8 PF00082.17 XP_011275409.1 - 2.4e-41 141.7 9.8 3.5e-41 141.2 6.8 1.3 1 0 0 1 1 1 1 Subtilase family Peptidase_S8 PF00082.17 XP_011275410.1 - 5.8e-44 150.3 3.9 7.5e-44 149.9 2.4 1.3 1 1 0 1 1 1 1 Subtilase family Prenyltrans_1 PF13243.1 XP_011275410.1 - 0.12 12.3 0.0 4.2 7.4 0.0 2.4 1 1 1 2 2 2 0 Prenyltransferase-like COesterase PF00135.23 XP_011275411.1 - 4.1e-101 339.3 0.8 5.3e-101 338.9 0.6 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 XP_011275411.1 - 7.1e-05 22.4 0.1 0.00023 20.8 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 XP_011275411.1 - 0.00031 20.0 0.0 0.00063 19.0 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 XP_011275411.1 - 0.013 15.2 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family GHL12 PF14882.1 XP_011275411.1 - 0.098 12.7 0.1 0.22 11.6 0.1 1.6 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 12 ERCC4 PF02732.10 XP_011275413.1 - 0.015 15.0 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 ERCC4 domain EIAV_GP90 PF00971.13 XP_011275413.1 - 0.065 11.6 1.1 0.36 9.2 0.1 1.9 1 1 1 2 2 2 0 EIAV coat protein, gp90 Methyltransf_23 PF13489.1 XP_011275415.1 - 7.4e-23 81.0 0.0 1.1e-22 80.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 XP_011275415.1 - 8.6e-17 61.4 0.0 1.7e-16 60.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 XP_011275415.1 - 2.2e-16 60.1 0.0 4.3e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 XP_011275415.1 - 1.6e-15 57.0 0.0 2.4e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 XP_011275415.1 - 2.9e-13 50.3 0.0 4.8e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 XP_011275415.1 - 4.3e-08 33.4 0.0 8.6e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 XP_011275415.1 - 1.4e-07 30.8 0.0 2e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 XP_011275415.1 - 4.6e-07 29.3 0.0 7.7e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 XP_011275415.1 - 7.8e-07 28.4 0.0 1.1e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.8 XP_011275415.1 - 1.9e-06 27.2 0.0 3.2e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.7 XP_011275415.1 - 2.4e-06 27.0 0.0 1.1e-05 24.8 0.0 2.0 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW NodS PF05401.6 XP_011275415.1 - 1.1e-05 24.9 0.0 1.5e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_32 PF13679.1 XP_011275415.1 - 0.00036 20.2 0.0 0.00065 19.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 XP_011275415.1 - 0.00041 20.3 0.0 0.00091 19.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 XP_011275415.1 - 0.0054 15.9 0.0 0.0079 15.3 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_9 PF08003.6 XP_011275415.1 - 0.0077 14.9 0.0 0.015 14.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) DREV PF05219.7 XP_011275415.1 - 0.0081 15.0 0.0 0.013 14.4 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase PCMT PF01135.14 XP_011275415.1 - 0.015 14.8 0.0 0.034 13.6 0.0 1.5 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.15 XP_011275415.1 - 0.046 12.7 0.1 0.13 11.2 0.0 1.8 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase TPMT PF05724.6 XP_011275415.1 - 0.13 11.7 0.0 0.37 10.1 0.0 1.7 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) YL1 PF05764.8 XP_011275416.1 - 2.9e-43 148.2 68.6 1.6e-37 129.4 24.6 6.6 3 2 3 6 6 6 2 YL1 nuclear protein YL1_C PF08265.6 XP_011275416.1 - 5.3e-13 48.2 0.1 8.6e-13 47.5 0.1 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Aha1_N PF09229.6 XP_011275417.1 - 1.6e-32 112.1 0.8 1.9e-32 111.9 0.6 1.1 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal Opy2 PF09463.5 XP_011275418.1 - 4.1e-06 26.7 22.1 6.2e-06 26.2 15.3 1.3 1 0 0 1 1 1 1 Opy2 protein Rick_17kDa_Anti PF05433.10 XP_011275418.1 - 0.062 12.9 4.0 0.11 12.1 2.8 1.3 1 0 0 1 1 1 0 Glycine zipper 2TM domain NatB_MDM20 PF09797.4 XP_011275419.1 - 1.6e-57 194.8 18.6 1.6e-57 194.8 12.9 1.9 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.1 XP_011275419.1 - 0.0026 18.0 0.4 0.073 13.4 0.0 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 XP_011275419.1 - 0.0041 17.7 0.0 0.022 15.4 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 XP_011275419.1 - 0.0094 16.5 0.0 36 5.3 0.0 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat Brix PF04427.13 XP_011275420.1 - 3.9e-38 131.0 0.1 5.3e-38 130.6 0.1 1.2 1 0 0 1 1 1 1 Brix domain DUF468 PF04318.7 XP_011275420.1 - 0.087 13.4 0.0 0.34 11.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF468) DHBP_synthase PF00926.14 XP_011275421.1 - 3.4e-82 274.3 0.0 3.8e-82 274.2 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase tRNA-synt_1b PF00579.20 XP_011275422.1 - 5.3e-21 75.0 0.0 8.5e-14 51.3 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (W and Y) Pkinase PF00069.20 XP_011275424.1 - 1.9e-67 227.1 0.0 3.4e-67 226.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011275424.1 - 1.1e-34 119.7 0.0 1.7e-34 119.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 XP_011275424.1 - 2.2e-10 39.9 0.0 6e-09 35.2 0.0 2.4 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 XP_011275424.1 - 2.6e-05 23.3 0.0 4.8e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 XP_011275424.1 - 0.0028 17.4 0.0 0.0047 16.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 XP_011275424.1 - 0.0049 16.2 0.1 0.0094 15.3 0.1 1.5 1 0 0 1 1 1 1 RIO1 family Ribosomal_L27e PF01777.13 XP_011275425.1 - 1.1e-33 115.1 8.4 1.6e-33 114.6 5.8 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 XP_011275425.1 - 0.00014 21.4 1.1 0.00036 20.1 0.8 1.8 1 0 0 1 1 1 1 KOW motif DUF1512 PF07431.7 XP_011275425.1 - 0.038 12.7 0.4 0.058 12.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1512) RasGAP PF00616.14 XP_011275426.1 - 2.4e-37 128.5 0.2 2.6e-36 125.1 0.2 3.0 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase RNase_T PF00929.19 XP_011275427.1 - 2.2e-27 96.3 0.1 4.6e-27 95.3 0.0 1.5 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 XP_011275427.1 - 0.0016 17.9 1.6 0.0033 16.9 0.1 2.3 2 1 0 2 2 2 1 3'-5' exonuclease ETRAMP PF09716.5 XP_011275427.1 - 5.2 7.1 8.8 17 5.4 6.1 1.9 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) SIN1 PF05422.7 XP_011275428.1 - 1.8e-34 119.1 0.1 4.6e-34 117.8 0.1 1.8 1 1 0 1 1 1 1 Stress-activated map kinase interacting protein 1 (SIN1) RBD PF02196.10 XP_011275428.1 - 0.00025 20.7 0.0 0.28 10.9 0.0 2.8 2 0 0 2 2 2 2 Raf-like Ras-binding domain HIG_1_N PF04588.8 XP_011275430.1 - 7.7e-05 22.3 1.8 0.00019 21.0 1.2 1.8 1 1 0 1 1 1 1 Hypoxia induced protein conserved region DUF727 PF05303.7 XP_011275431.1 - 0.0003 20.5 0.2 0.26 11.0 0.1 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF727) Ribosomal_L19 PF01245.15 XP_011275432.1 - 5.5e-12 45.4 0.1 7.1e-12 45.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L19 WBS_methylT PF12589.3 XP_011275433.1 - 1.8e-15 57.1 7.1 3.5e-15 56.2 4.9 1.5 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 XP_011275433.1 - 6.2e-11 42.6 0.0 1.3e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 XP_011275433.1 - 2.8e-07 30.8 0.0 8.3e-07 29.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 XP_011275433.1 - 2.4e-05 24.1 0.0 3.5e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 XP_011275433.1 - 6.3e-05 23.3 0.0 0.00027 21.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 XP_011275433.1 - 7.4e-05 22.3 0.0 0.00034 20.2 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 XP_011275433.1 - 0.0028 18.2 0.1 0.0081 16.7 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.8 XP_011275433.1 - 0.0091 16.1 0.0 0.02 14.9 0.0 1.6 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase PCMT PF01135.14 XP_011275433.1 - 0.011 15.2 0.0 0.059 12.8 0.0 2.1 3 0 0 3 3 3 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF2271 PF10029.4 XP_011275433.1 - 0.018 14.5 0.0 0.026 14.0 0.0 1.2 1 0 0 1 1 1 0 Predicted periplasmic protein (DUF2271) Methyltransf_26 PF13659.1 XP_011275433.1 - 0.032 14.2 0.0 0.074 13.0 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain MBOAT PF03062.14 XP_011275434.1 - 4.6e-47 160.7 32.4 6.9e-45 153.5 22.5 2.5 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 XP_011275434.1 - 5.6e-05 23.1 3.6 0.00018 21.5 2.5 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family CotH PF08757.6 XP_011275434.1 - 0.0041 16.4 0.6 0.0068 15.6 0.4 1.2 1 0 0 1 1 1 1 CotH protein Serglycin PF04360.7 XP_011275434.1 - 0.008 15.9 0.4 0.015 15.0 0.3 1.4 1 0 0 1 1 1 1 Serglycin Peptidase_M76 PF09768.4 XP_011275435.1 - 6.9e-74 247.0 2.3 9.2e-74 246.6 1.6 1.2 1 0 0 1 1 1 1 Peptidase M76 family Ank_5 PF13857.1 XP_011275436.1 - 2.2e-15 56.3 0.0 2.6e-11 43.3 0.0 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 XP_011275436.1 - 2.2e-13 50.3 0.1 1.5e-12 47.7 0.0 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 XP_011275436.1 - 3.9e-13 49.5 0.2 4.6e-08 33.3 0.0 3.4 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.25 XP_011275436.1 - 4.8e-11 41.8 1.8 1.5e-09 37.1 0.1 3.4 3 1 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.1 XP_011275436.1 - 1.6e-09 37.0 0.2 1.1e-06 28.2 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeat DUF544 PF04424.8 XP_011275437.1 - 1.3e-22 79.8 0.1 2.4e-22 78.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF544) DUF505 PF04458.7 XP_011275438.1 - 0.072 11.2 0.4 0.1 10.6 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF505) PaaX_C PF08223.6 XP_011275438.1 - 0.24 11.0 0.0 0.47 10.1 0.0 1.4 1 0 0 1 1 1 0 PaaX-like protein C-terminal domain CN_hydrolase PF00795.17 XP_011275439.1 - 5.4e-25 87.8 0.0 6.8e-25 87.5 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DUF4451 PF14616.1 XP_011275440.1 - 0.063 13.0 5.0 0.23 11.2 3.4 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4451) Zn_clus PF00172.13 XP_011275441.1 - 1.5e-07 31.1 7.4 2.8e-07 30.3 5.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.13 XP_011275442.1 - 3.5e-07 30.0 9.4 6e-07 29.2 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF669 PF05037.8 XP_011275442.1 - 0.061 13.2 0.1 0.39 10.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF669) Zn_clus PF00172.13 XP_011275444.1 - 6.5e-08 32.3 9.2 1.2e-07 31.4 6.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FA_desaturase PF00487.19 XP_011275445.1 - 4.5e-22 78.7 24.0 6.4e-22 78.2 16.6 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 XP_011275445.1 - 3e-06 27.2 0.0 5.6e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) TMEM213 PF15192.1 XP_011275445.1 - 0.033 14.1 0.4 0.079 12.9 0.3 1.6 1 0 0 1 1 1 0 TMEM213 family Aldo_ket_red PF00248.16 XP_011275446.1 - 6.5e-41 140.0 0.0 8.5e-41 139.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Sterol-sensing PF12349.3 XP_011275447.1 - 4.9e-30 104.0 6.1 9.4e-30 103.0 4.2 1.5 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 XP_011275447.1 - 3.2e-12 45.2 15.0 9.9e-12 43.6 10.4 1.7 1 1 0 1 1 1 1 Patched family Synaptobrevin PF00957.16 XP_011275447.1 - 0.046 13.3 5.4 0.4 10.3 0.4 3.4 3 0 0 3 3 3 0 Synaptobrevin BAR PF03114.13 XP_011275448.1 - 1.7e-35 122.5 0.2 2.1e-35 122.3 0.1 1.1 1 0 0 1 1 1 1 BAR domain HAS-barrel PF09378.5 XP_011275448.1 - 0.028 14.2 0.1 0.24 11.3 0.0 2.1 2 0 0 2 2 2 0 HAS barrel domain DUF2303 PF10065.4 XP_011275448.1 - 0.082 11.7 0.1 0.1 11.4 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2303) Pkinase PF00069.20 XP_011275449.1 - 2.4e-62 210.4 0.0 5e-62 209.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011275449.1 - 7.9e-27 93.9 0.0 1.3e-26 93.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 XP_011275449.1 - 0.015 14.2 0.0 0.03 13.2 0.0 1.5 1 0 0 1 1 1 0 Kinase-like DUF1741 PF08427.5 XP_011275450.1 - 0.03 13.7 1.2 0.064 12.7 0.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1741) Grp1_Fun34_YaaH PF01184.14 XP_011275451.1 - 4.6e-94 313.5 18.1 5.6e-94 313.3 12.6 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Lipase_3 PF01764.20 XP_011275452.1 - 5.4e-22 77.9 0.0 3.6e-21 75.2 0.0 2.2 1 1 0 1 1 1 1 Lipase (class 3) Endonuc-BsobI PF09194.5 XP_011275452.1 - 0.0048 15.8 0.1 0.26 10.2 0.0 2.1 2 0 0 2 2 2 2 Restriction endonuclease BsobI DUF2974 PF11187.3 XP_011275452.1 - 0.016 14.5 0.0 0.56 9.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) PGAP1 PF07819.8 XP_011275452.1 - 0.054 13.0 0.0 0.096 12.2 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_5 PF12695.2 XP_011275452.1 - 0.13 12.0 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family S-methyl_trans PF02574.11 XP_011275453.1 - 1.2e-59 202.0 0.0 1.5e-59 201.7 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase PSII_BNR PF14870.1 XP_011275453.1 - 0.046 12.6 0.0 0.07 12.1 0.0 1.2 1 0 0 1 1 1 0 Photosynthesis system II assembly factor YCF48 Kelch_1 PF01344.20 XP_011275453.1 - 0.055 13.0 0.8 0.36 10.4 0.0 2.2 2 0 0 2 2 2 0 Kelch motif Grp1_Fun34_YaaH PF01184.14 XP_011275454.1 - 1.1e-91 305.8 19.1 1.4e-91 305.5 13.2 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Mpv17_PMP22 PF04117.7 XP_011275455.1 - 3e-25 87.6 4.7 5.9e-25 86.6 3.2 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family Scm3 PF10384.4 XP_011275456.1 - 6.5e-10 38.3 2.9 1.4e-09 37.2 2.0 1.6 1 0 0 1 1 1 1 Centromere protein Scm3 ABC1 PF03109.11 XP_011275457.1 - 3.3e-32 110.9 0.0 7.3e-32 109.8 0.0 1.6 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.17 XP_011275457.1 - 0.00031 20.1 0.0 0.0018 17.6 0.0 2.2 3 0 0 3 3 3 1 RIO1 family IncA PF04156.9 XP_011275458.1 - 0.013 15.0 38.0 0.33 10.5 11.6 3.1 1 1 2 3 3 3 0 IncA protein RRM_1 PF00076.17 XP_011275458.1 - 0.027 14.0 0.1 0.17 11.5 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PilJ PF13675.1 XP_011275458.1 - 0.15 12.4 2.6 0.55 10.5 0.3 2.6 1 1 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term CENP-Q PF13094.1 XP_011275458.1 - 0.2 11.6 34.8 0.21 11.5 14.4 2.6 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Atg14 PF10186.4 XP_011275458.1 - 0.66 8.8 26.6 1.1 8.0 10.5 2.2 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Bcr-Abl_Oligo PF09036.5 XP_011275458.1 - 0.9 9.5 4.0 6.8 6.7 0.0 3.3 3 1 0 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain Tropomyosin_1 PF12718.2 XP_011275458.1 - 6.8 6.5 45.7 2.5 7.9 23.2 2.9 1 1 3 4 4 4 0 Tropomyosin like Zn_clus PF00172.13 XP_011275459.1 - 1.9e-09 37.2 8.3 3.5e-09 36.4 5.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sin_N PF04801.8 XP_011275460.1 - 1.5e-26 93.2 0.2 2.8e-26 92.3 0.1 1.4 1 1 0 1 1 1 1 Sin-like protein conserved region Mannosyl_trans3 PF11051.3 XP_011275461.1 - 6.5e-90 301.1 0.0 1.3e-89 300.1 0.0 1.5 2 0 0 2 2 2 1 Mannosyltransferase putative DUF1980 PF09323.5 XP_011275461.1 - 0.012 15.4 4.6 0.025 14.3 1.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Glyco_transf_15 PF01793.11 XP_011275462.1 - 3e-114 381.4 19.5 3.4e-114 381.2 13.5 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase GTP_EFTU PF00009.22 XP_011275463.1 - 2.1e-56 190.3 0.1 3.3e-56 189.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 XP_011275463.1 - 3.6e-25 87.6 0.0 1.1e-24 86.0 0.0 1.9 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 XP_011275463.1 - 1.6e-19 69.5 0.0 8.3e-18 64.0 0.0 2.5 1 1 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 XP_011275463.1 - 1.4e-09 37.9 1.9 1.6e-09 37.7 0.2 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 XP_011275463.1 - 0.0037 17.1 0.1 0.0092 15.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase IF-2B PF01008.12 XP_011275464.1 - 4.3e-76 255.5 0.0 4.9e-76 255.4 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family HAD PF12710.2 XP_011275465.1 - 3.6e-19 69.6 0.1 4.8e-19 69.2 0.1 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 XP_011275465.1 - 1.5e-10 40.6 0.2 2.1e-10 40.2 0.1 1.2 1 0 0 1 1 1 1 Putative Phosphatase HAD_2 PF13419.1 XP_011275465.1 - 5.4e-06 26.7 0.0 0.00011 22.4 0.0 2.3 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 XP_011275465.1 - 1.1e-05 24.9 0.4 6.4e-05 22.3 0.0 2.0 1 1 1 2 2 2 1 Pyrimidine 5'-nucleotidase (UMPH-1) P3A PF08727.6 XP_011275465.1 - 0.037 13.3 0.0 3.4 7.0 0.0 2.9 2 1 0 2 2 2 0 Poliovirus 3A protein like Hydrolase PF00702.21 XP_011275465.1 - 0.063 13.6 0.8 0.31 11.4 0.0 2.1 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase SpoU_sub_bind PF08032.7 XP_011275465.1 - 0.083 13.0 0.0 0.29 11.3 0.0 1.9 1 1 0 1 1 1 0 RNA 2'-O ribose methyltransferase substrate binding Glyco_hydro_17 PF00332.13 XP_011275466.1 - 1.3e-08 34.2 1.1 3.2e-08 32.9 0.8 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 OppC_N PF12911.2 XP_011275466.1 - 0.055 12.8 0.4 0.14 11.5 0.3 1.6 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C DUF3595 PF12166.3 XP_011275466.1 - 1.5 7.5 8.8 0.073 11.8 1.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3595) Alg6_Alg8 PF03155.10 XP_011275467.1 - 5e-151 503.7 32.0 6e-151 503.4 22.2 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family adh_short PF00106.20 XP_011275468.1 - 2.5e-17 63.2 0.0 3.1e-17 62.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 XP_011275468.1 - 1.7e-13 50.9 1.0 2e-13 50.7 0.7 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 XP_011275468.1 - 8.1e-11 41.9 0.0 1.1e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 XP_011275468.1 - 0.047 13.1 0.2 0.11 11.9 0.1 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DXP_reductoisom PF02670.11 XP_011275468.1 - 0.073 13.6 0.4 0.3 11.6 0.1 2.0 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase adh_short PF00106.20 XP_011275469.1 - 2.8e-19 69.6 0.0 3.7e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 XP_011275469.1 - 8.1e-15 55.2 0.9 9.9e-15 54.9 0.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 XP_011275469.1 - 5.2e-12 45.8 0.0 1.5e-11 44.3 0.0 1.6 1 1 1 2 2 2 1 KR domain NAD_binding_10 PF13460.1 XP_011275469.1 - 1.2e-05 25.4 0.0 1.7e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding DUF4335 PF14233.1 XP_011275470.1 - 0.061 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4335) Glyco_hydro_85 PF03644.8 XP_011275471.1 - 4.9e-88 295.2 8.6 7.4e-88 294.6 6.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 Integrase_Zn PF02022.14 XP_011275471.1 - 0.026 13.9 0.0 0.19 11.2 0.0 2.2 2 0 0 2 2 2 0 Integrase Zinc binding domain SecY PF00344.15 XP_011275472.1 - 2.7e-92 309.3 11.4 3.4e-92 309.0 7.9 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 XP_011275472.1 - 4.5e-18 64.4 0.1 2.3e-17 62.2 0.1 2.3 2 0 0 2 2 2 1 Plug domain of Sec61p SdpI PF13630.1 XP_011275472.1 - 0.068 12.8 0.1 0.068 12.8 0.1 3.2 4 0 0 4 4 4 0 SdpI/YhfL protein family Claudin_3 PF06653.6 XP_011275472.1 - 0.34 10.6 0.1 0.34 10.6 0.0 2.9 4 0 0 4 4 4 0 Tight junction protein, Claudin-like MFS_1 PF07690.11 XP_011275473.1 - 1.4e-13 50.3 33.2 2.4e-12 46.2 2.1 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily RNB PF00773.14 XP_011275474.1 - 1.3e-94 317.2 0.1 2e-94 316.5 0.0 1.3 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 XP_011275474.1 - 1.4e-13 51.1 1.7 4.1e-13 49.5 1.1 1.9 1 0 0 1 1 1 1 PIN domain OB_RNB PF08206.6 XP_011275474.1 - 0.067 12.6 0.0 0.21 11.1 0.0 1.8 1 0 0 1 1 1 0 Ribonuclease B OB domain Baculo_8kDa PF06096.6 XP_011275474.1 - 0.15 11.9 3.0 1.9 8.4 0.2 2.7 2 0 0 2 2 2 0 Baculoviridae 8.2 KDa protein FBPase PF00316.15 XP_011275475.1 - 5.3e-133 442.8 0.0 6e-133 442.6 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Inositol_P PF00459.20 XP_011275475.1 - 0.021 14.1 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 Inositol monophosphatase family PAT1 PF09770.4 XP_011275476.1 - 5.5 5.0 41.2 7.5 4.6 28.6 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 THUMP PF02926.12 XP_011275477.1 - 7.2e-22 77.8 1.4 1.8e-21 76.5 1.0 1.7 1 0 0 1 1 1 1 THUMP domain Sec15 PF04091.7 XP_011275478.1 - 1.2e-76 258.0 14.8 1.2e-76 258.0 10.2 3.7 3 1 1 4 4 4 1 Exocyst complex subunit Sec15-like PadR PF03551.9 XP_011275478.1 - 0.019 14.7 0.0 0.063 13.0 0.0 1.8 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family adh_short PF00106.20 XP_011275479.1 - 1.8e-16 60.5 0.0 2.2e-16 60.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 XP_011275479.1 - 6.1e-08 32.7 0.0 7.6e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 XP_011275479.1 - 1.3e-06 28.2 0.0 1.6e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 XP_011275479.1 - 0.00028 20.3 0.1 0.00063 19.2 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 XP_011275479.1 - 0.0015 18.5 0.3 0.003 17.5 0.2 1.5 1 0 0 1 1 1 1 NADH(P)-binding DUF830 PF05708.7 XP_011275479.1 - 0.035 14.0 0.0 0.062 13.2 0.0 1.3 1 0 0 1 1 1 0 Orthopoxvirus protein of unknown function (DUF830) ADH_zinc_N PF00107.21 XP_011275479.1 - 0.039 13.5 0.0 0.072 12.6 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase NAD_binding_4 PF07993.7 XP_011275479.1 - 0.06 12.2 0.1 0.68 8.8 0.0 2.1 2 1 0 2 2 2 0 Male sterility protein PTR2 PF00854.16 XP_011275480.1 - 1.3e-43 149.2 8.6 1.3e-43 149.2 6.0 1.6 2 0 0 2 2 2 1 POT family PTR2 PF00854.16 XP_011275481.1 - 1.9e-42 145.4 7.8 3.4e-42 144.5 5.4 1.4 1 0 0 1 1 1 1 POT family MFS_1 PF07690.11 XP_011275481.1 - 3.8e-13 48.8 33.9 9.1e-10 37.7 13.7 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 XP_011275481.1 - 3.7e-05 23.1 0.2 3.7e-05 23.1 0.1 1.9 3 0 0 3 3 3 1 Nodulin-like PTR2 PF00854.16 XP_011275482.1 - 3.8e-40 137.8 6.3 6.2e-40 137.1 4.4 1.3 1 0 0 1 1 1 1 POT family MFS_1 PF07690.11 XP_011275482.1 - 1.5e-16 60.0 32.5 4.5e-12 45.3 13.3 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 XP_011275482.1 - 3.4e-05 23.2 0.3 9.5e-05 21.7 0.2 1.7 1 0 0 1 1 1 1 Nodulin-like PUCC PF03209.10 XP_011275482.1 - 0.016 13.9 3.3 0.074 11.7 0.1 2.3 2 0 0 2 2 2 0 PUCC protein DUF1129 PF06570.6 XP_011275482.1 - 1.2 8.4 5.1 5.5 6.2 0.1 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF1129) Rhodanese PF00581.15 XP_011275483.1 - 3.2e-15 56.4 0.0 8.3e-15 55.1 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Pkinase PF00069.20 XP_011275484.1 - 2.7e-59 200.4 0.9 3.9e-59 199.9 0.6 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011275484.1 - 1.8e-35 122.3 0.0 2.6e-35 121.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 XP_011275484.1 - 1.1e-10 40.9 0.0 2e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like zf-C2H2 PF00096.21 XP_011275485.1 - 2.4e-11 43.2 14.9 2.2e-05 24.5 2.4 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 XP_011275485.1 - 9.9e-11 41.1 13.8 3.3e-05 23.9 2.4 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 XP_011275485.1 - 2e-07 30.9 7.3 0.00083 19.4 1.1 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 XP_011275485.1 - 2.9e-07 30.4 21.0 6.8e-06 26.1 3.8 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.2 XP_011275485.1 - 9.1e-06 25.7 6.4 0.0016 18.5 1.6 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-BED PF02892.10 XP_011275485.1 - 2.3e-05 24.0 3.2 0.018 14.7 0.5 2.8 2 0 0 2 2 2 2 BED zinc finger zf-C2H2_2 PF12756.2 XP_011275485.1 - 0.0016 18.5 6.5 0.088 12.9 0.6 2.9 2 1 1 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 XP_011275485.1 - 0.009 15.8 6.5 0.0097 15.7 1.1 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger PyrI_C PF02748.10 XP_011275485.1 - 0.19 11.1 2.3 0.41 10.1 0.1 2.2 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain FixG_C PF11614.3 XP_011275485.1 - 0.23 11.5 5.2 0.46 10.5 3.6 1.5 1 0 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase SR-25 PF10500.4 XP_011275485.1 - 0.23 10.9 10.7 0.35 10.3 7.4 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein zf-DBF PF07535.7 XP_011275485.1 - 3 7.5 6.7 2.3 7.9 0.5 2.6 2 0 0 2 2 2 0 DBF zinc finger DUF3812 PF12757.2 XP_011275486.1 - 1.6e-28 99.2 3.0 1.6e-28 99.2 2.1 4.5 2 2 1 4 4 4 1 Protein of unknown function (DUF3812) Gly-zipper_OmpA PF13436.1 XP_011275486.1 - 0.55 9.9 5.8 0.17 11.5 1.2 2.2 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain ADH_zinc_N PF00107.21 XP_011275487.1 - 1.9e-29 101.8 0.9 2.8e-29 101.2 0.6 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 XP_011275487.1 - 3.7e-18 65.2 0.2 1.8e-17 63.0 0.1 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N PF08240.7 XP_011275488.1 - 4.4e-29 100.4 1.7 6e-29 99.9 0.2 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 XP_011275488.1 - 8.8e-29 99.6 0.7 1.3e-28 99.1 0.5 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 XP_011275488.1 - 1.3e-05 26.0 0.3 3e-05 24.9 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AA_permease_2 PF13520.1 XP_011275490.1 - 1e-69 235.1 33.2 1e-69 235.1 23.0 1.2 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 XP_011275491.1 - 9e-69 232.0 37.4 1.2e-68 231.6 25.9 1.2 1 0 0 1 1 1 1 Amino acid permease Polyketide_cyc2 PF10604.4 XP_011275492.1 - 9.9e-09 35.4 0.0 1.2e-08 35.2 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.15 XP_011275492.1 - 0.074 13.0 0.0 0.089 12.7 0.0 1.3 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport MFS_1 PF07690.11 XP_011275493.1 - 3.6e-23 81.8 21.6 5.1e-23 81.3 14.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3671 PF12420.3 XP_011275493.1 - 5.9 6.9 6.8 27 4.7 2.0 2.7 1 1 1 2 2 2 0 Protein of unknown function GCV_H PF01597.14 XP_011275494.1 - 2.4e-42 143.4 0.2 2.9e-42 143.1 0.1 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.17 XP_011275494.1 - 1.3e-05 24.7 0.8 2.9e-05 23.6 0.1 1.8 1 1 1 2 2 2 1 Biotin-requiring enzyme RnfC_N PF13375.1 XP_011275494.1 - 3e-05 23.6 0.0 4.5e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain BolA PF01722.13 XP_011275495.1 - 4.3e-29 100.2 2.1 6.4e-29 99.7 1.5 1.3 1 0 0 1 1 1 1 BolA-like protein Gln-synt_C PF00120.19 XP_011275496.1 - 1.4e-65 221.0 0.0 1.7e-65 220.7 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 XP_011275496.1 - 1.2e-18 66.4 0.0 2e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain MVL PF12151.3 XP_011275496.1 - 0.091 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Mannan-binding protein Mannosyl_trans3 PF11051.3 XP_011275497.1 - 1.3e-80 270.6 0.6 2.2e-80 269.8 0.4 1.4 1 0 0 1 1 1 1 Mannosyltransferase putative V-ATPase_H_N PF03224.9 XP_011275498.1 - 1.2e-58 198.6 21.7 1.2e-58 198.6 15.0 2.0 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 XP_011275498.1 - 1.1e-30 105.9 4.2 1.1e-30 105.9 2.9 4.0 4 1 0 4 4 4 1 V-ATPase subunit H HEAT PF02985.17 XP_011275498.1 - 2.8e-05 23.8 0.0 0.019 14.9 0.0 3.7 3 0 0 3 3 3 1 HEAT repeat DUF1039 PF06287.6 XP_011275498.1 - 0.014 15.2 0.9 5.5 6.9 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1039) HEAT_2 PF13646.1 XP_011275498.1 - 0.015 15.5 0.0 1.2 9.4 0.0 3.3 2 2 0 2 2 2 0 HEAT repeats DUF2019 PF09450.5 XP_011275498.1 - 0.07 12.9 0.2 0.3 10.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2019) PCI PF01399.22 XP_011275500.1 - 8.4e-15 54.9 1.4 2.3e-14 53.6 0.5 2.1 1 1 1 2 2 2 1 PCI domain Tmemb_14 PF03647.8 XP_011275501.1 - 1.2e-14 54.4 2.1 1.4e-14 54.2 1.4 1.2 1 0 0 1 1 1 1 Transmembrane proteins 14C G-gamma PF00631.17 XP_011275502.1 - 4e-21 74.5 0.0 5.9e-21 73.9 0.0 1.3 1 0 0 1 1 1 1 GGL domain BRE1 PF08647.6 XP_011275502.1 - 0.24 11.3 3.2 0.34 10.8 2.2 1.2 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Evr1_Alr PF04777.8 XP_011275503.1 - 1.9e-27 94.9 0.1 2.8e-27 94.4 0.1 1.3 1 0 0 1 1 1 1 Erv1 / Alr family Herpes_UL69 PF05459.7 XP_011275503.1 - 0.095 11.8 0.1 0.43 9.6 0.0 1.9 1 1 1 2 2 2 0 Herpesvirus transcriptional regulator family TIP41 PF04176.8 XP_011275504.1 - 1.3e-74 249.3 0.4 1.8e-74 248.9 0.3 1.2 1 0 0 1 1 1 1 TIP41-like family TPR_8 PF13181.1 XP_011275505.1 - 1.4e-06 27.6 0.2 0.0042 16.7 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 XP_011275505.1 - 4.9e-05 22.9 0.0 0.01 15.7 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 XP_011275505.1 - 0.002 18.1 0.0 0.058 13.6 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 XP_011275505.1 - 0.013 15.8 0.0 0.39 11.0 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 XP_011275505.1 - 0.015 14.9 0.0 0.14 11.8 0.0 2.4 1 1 2 3 3 3 0 TPR repeat TPR_20 PF14561.1 XP_011275505.1 - 0.019 15.0 0.0 0.085 12.9 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 XP_011275505.1 - 0.022 15.4 0.0 0.078 13.6 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat ChAPs PF09295.5 XP_011275505.1 - 0.034 12.9 0.0 0.047 12.4 0.0 1.3 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) Mgr1 PF08602.5 XP_011275505.1 - 0.089 11.7 0.1 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit TPR_1 PF00515.23 XP_011275505.1 - 0.098 12.3 0.0 28 4.5 0.0 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat eIF-5_eIF-2B PF01873.12 XP_011275506.1 - 1.3e-37 128.2 0.0 2.4e-37 127.3 0.0 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 XP_011275506.1 - 6e-27 93.4 2.4 6e-27 93.4 1.6 2.5 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon DUF2387 PF09526.5 XP_011275506.1 - 0.032 14.1 0.1 0.089 12.7 0.1 1.7 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) MMR_HSR1 PF01926.18 XP_011275507.1 - 2.5e-17 62.8 0.1 3.7e-15 55.8 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 XP_011275507.1 - 1.5e-07 30.8 0.1 1.4e-05 24.4 0.0 2.7 3 0 0 3 3 3 1 Ferrous iron transport protein B DUF258 PF03193.11 XP_011275507.1 - 0.00035 19.7 0.0 0.00068 18.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 XP_011275507.1 - 0.0041 16.2 0.0 0.0099 14.9 0.0 1.6 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.18 XP_011275507.1 - 0.018 14.8 0.5 0.018 14.8 0.4 2.8 3 1 0 3 3 3 0 Dynamin family Miro PF08477.8 XP_011275507.1 - 0.035 14.5 0.1 0.091 13.2 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein Glyco_transf_25 PF01755.12 XP_011275507.1 - 0.041 13.5 0.5 0.19 11.3 0.1 2.3 2 0 0 2 2 2 0 Glycosyltransferase family 25 (LPS biosynthesis protein) RRM_6 PF14259.1 XP_011275509.1 - 4.2e-30 103.5 3.0 1.7e-09 37.5 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 XP_011275509.1 - 1.5e-27 95.0 4.5 5.4e-09 35.5 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 XP_011275509.1 - 7.7e-16 57.6 4.5 0.00018 21.2 0.1 4.7 4 1 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM PF10378.4 XP_011275509.1 - 0.0014 18.2 0.4 0.0042 16.6 0.3 1.9 1 0 0 1 1 1 1 Putative RRM domain Nup35_RRM_2 PF14605.1 XP_011275509.1 - 0.0022 17.7 0.3 0.043 13.5 0.0 2.7 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif NID PF07292.8 XP_011275509.1 - 0.0088 16.0 0.0 1.6 8.8 0.0 3.2 3 0 0 3 3 3 1 Nmi/IFP 35 domain (NID) RNA_bind PF08675.6 XP_011275509.1 - 0.14 12.1 0.1 3.6 7.6 0.0 2.9 3 0 0 3 3 3 0 RNA binding domain LRR_8 PF13855.1 XP_011275512.1 - 0.011 15.4 10.5 0.22 11.2 0.0 4.5 4 1 2 6 6 6 0 Leucine rich repeat LRR_7 PF13504.1 XP_011275512.1 - 0.26 11.6 8.1 1.7 9.1 0.0 5.2 6 0 0 6 6 6 0 Leucine rich repeat LRR_1 PF00560.28 XP_011275512.1 - 4.5 7.6 7.3 68 4.0 0.1 4.7 4 0 0 4 4 4 0 Leucine Rich Repeat Cu_amine_oxid PF01179.15 XP_011275513.1 - 1e-92 311.0 1.9 1.3e-92 310.6 1.3 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.5 XP_011275513.1 - 1.9e-18 66.1 0.2 7.8e-18 64.1 0.1 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.11 XP_011275513.1 - 0.0041 17.1 0.0 0.0089 16.0 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain NAD_kinase PF01513.16 XP_011275514.1 - 5.3e-52 176.3 0.0 9.5e-52 175.5 0.0 1.3 1 1 0 1 1 1 1 ATP-NAD kinase Dsl1_C PF11989.3 XP_011275515.1 - 4.3e-24 85.1 5.5 4.3e-24 85.1 3.8 3.2 3 1 0 4 4 4 1 Retrograde transport protein Dsl1 C terminal Dsl1_N PF11988.3 XP_011275515.1 - 1.7e-13 50.1 10.1 1.7e-13 50.1 7.0 2.5 1 1 1 2 2 2 2 Retrograde transport protein Dsl1 N terminal eIF3_subunit PF08597.5 XP_011275515.1 - 0.00041 19.9 17.1 0.00092 18.8 11.8 1.5 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit CENP-T PF15511.1 XP_011275515.1 - 0.45 9.7 10.5 0.67 9.1 7.3 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T COPI_C PF06957.6 XP_011275515.1 - 3.6 5.9 8.7 5.9 5.3 6.0 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Abhydro_lipase PF04083.11 XP_011275516.1 - 9.7e-23 79.3 2.1 1.2e-22 79.0 0.7 1.8 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 XP_011275516.1 - 4.6e-14 52.5 0.0 7.5e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 XP_011275516.1 - 0.00016 21.6 0.0 0.00031 20.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 XP_011275516.1 - 0.00063 19.5 0.0 0.0024 17.6 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 XP_011275516.1 - 0.0012 18.3 0.0 0.48 9.8 0.0 2.4 2 0 0 2 2 2 2 Serine hydrolase (FSH1) MBOAT PF03062.14 XP_011275518.1 - 5.7e-62 209.6 20.7 1.2e-61 208.5 14.0 1.8 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family SNase PF00565.12 XP_011275519.1 - 1.1e-23 83.5 0.0 1.5e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue MAD PF05557.8 XP_011275520.1 - 8.6e-44 149.7 89.3 1.2e-43 149.3 61.9 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein DUF2937 PF11157.3 XP_011275520.1 - 0.29 10.4 1.7 0.95 8.7 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2937) UQ_con PF00179.21 XP_011275521.1 - 3.1e-18 65.5 0.0 3.4e-18 65.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 XP_011275521.1 - 0.0017 18.2 0.1 0.0021 17.9 0.1 1.3 1 1 0 1 1 1 1 RWD domain ELYS PF13934.1 XP_011275522.1 - 7.7e-10 38.8 0.2 1.2e-09 38.2 0.1 1.3 1 0 0 1 1 1 1 Nuclear pore complex assembly Flagellin_IN PF07196.8 XP_011275522.1 - 0.04 13.9 0.0 0.089 12.7 0.0 1.5 1 0 0 1 1 1 0 Flagellin hook IN motif Aldo_ket_red PF00248.16 XP_011275523.1 - 1.4e-50 171.7 0.0 1.9e-50 171.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 XP_011275524.1 - 1.8e-42 145.0 0.0 2.5e-42 144.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Ribosomal_L17 PF01196.14 XP_011275524.1 - 0.082 13.4 0.2 0.28 11.7 0.2 1.9 1 1 0 1 1 1 0 Ribosomal protein L17 RHH_1 PF01402.16 XP_011275524.1 - 0.091 12.6 0.2 0.32 10.9 0.0 2.1 3 0 0 3 3 3 0 Ribbon-helix-helix protein, copG family Mito_carr PF00153.22 XP_011275525.1 - 1e-62 207.8 7.7 1.1e-23 82.7 0.1 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein Glug PF07581.7 XP_011275525.1 - 9.3 6.6 7.4 36 4.8 0.4 3.2 3 0 0 3 3 3 0 The GLUG motif Peptidase_M22 PF00814.20 XP_011275526.1 - 2.9e-64 217.1 0.0 3.4e-64 216.9 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family BcrAD_BadFG PF01869.15 XP_011275526.1 - 0.073 12.3 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family Nse4_C PF08743.5 XP_011275527.1 - 8.4e-23 80.2 0.0 2.4e-22 78.7 0.0 1.8 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 XP_011275527.1 - 0.0082 15.9 0.1 0.0082 15.9 0.1 3.0 2 2 0 2 2 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE Daxx PF03344.10 XP_011275527.1 - 0.091 11.2 25.4 0.16 10.4 17.6 1.3 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 XP_011275527.1 - 0.14 10.1 26.1 0.2 9.5 18.1 1.2 1 0 0 1 1 1 0 Nop14-like family Paf1 PF03985.8 XP_011275527.1 - 0.48 9.1 22.0 0.8 8.3 15.2 1.3 1 0 0 1 1 1 0 Paf1 DUF2890 PF11081.3 XP_011275527.1 - 0.69 9.9 18.0 1.8 8.5 12.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) CDC45 PF02724.9 XP_011275527.1 - 1.4 6.9 19.7 1.8 6.4 13.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop53 PF07767.6 XP_011275527.1 - 2 7.2 21.4 3.6 6.4 14.9 1.4 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CobT PF06213.7 XP_011275527.1 - 4.9 6.2 23.2 8.4 5.4 16.1 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT NOA36 PF06524.7 XP_011275527.1 - 5.6 6.1 20.4 10 5.2 14.2 1.4 1 0 0 1 1 1 0 NOA36 protein Vfa1 PF08432.5 XP_011275527.1 - 5.9 6.8 17.0 3 7.8 9.9 1.9 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DUF1510 PF07423.6 XP_011275527.1 - 7.6 5.8 20.7 17 4.7 14.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DNA_mis_repair PF01119.14 XP_011275528.1 - 6.2e-30 103.1 1.0 1e-29 102.3 0.1 1.9 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 XP_011275528.1 - 1.6e-12 47.2 1.6 1.8e-12 47.1 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 XP_011275528.1 - 1.2e-10 41.0 0.0 6.2e-10 38.7 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Zn_clus PF00172.13 XP_011275529.1 - 9.4e-08 31.8 6.7 1.7e-07 31.0 4.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3082 PF11282.3 XP_011275530.1 - 0.0077 16.2 1.3 0.05 13.6 0.1 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF3082) UPF0093 PF03653.8 XP_011275530.1 - 0.017 15.0 0.9 0.026 14.4 0.6 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0093) Intg_mem_TP0381 PF09529.5 XP_011275530.1 - 0.077 12.2 2.6 0.11 11.6 1.8 1.3 1 1 0 1 1 1 0 Integral membrane protein (intg_mem_TP0381) PsbX PF06596.6 XP_011275530.1 - 5.1 6.8 7.2 18 5.1 0.1 2.4 2 0 0 2 2 2 0 Photosystem II reaction centre X protein (PsbX) Baculo_11_kDa PF06143.6 XP_011275530.1 - 7.3 6.0 6.3 3.3 7.1 2.3 1.8 1 1 1 2 2 2 0 Baculovirus 11 kDa family Aldedh PF00171.17 XP_011275531.1 - 9.5e-178 591.2 0.0 1.1e-177 591.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Erp_C PF06780.6 XP_011275531.1 - 0.057 13.2 0.2 0.12 12.2 0.2 1.5 1 0 0 1 1 1 0 Erp protein C-terminus LisH PF08513.6 XP_011275532.1 - 1.7e-05 24.3 1.1 2.8e-05 23.7 0.8 1.3 1 0 0 1 1 1 1 LisH Borrelia_P83 PF05262.6 XP_011275532.1 - 0.54 8.4 15.9 0.86 7.7 11.0 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein DnaJ PF00226.26 XP_011275533.1 - 2.2e-24 84.9 2.6 2.5e-24 84.7 1.0 1.7 2 0 0 2 2 2 1 DnaJ domain DUF1977 PF09320.6 XP_011275533.1 - 1.8e-20 73.1 1.1 2.8e-20 72.5 0.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) Vezatin PF12632.2 XP_011275534.1 - 3.3e-23 82.0 19.5 3.3e-23 82.0 13.5 2.2 2 0 0 2 2 2 1 Mysoin-binding motif of peroxisomes UPF0449 PF15136.1 XP_011275534.1 - 1.1 9.5 8.0 6.2 7.0 0.1 3.5 3 0 0 3 3 3 0 Uncharacterised protein family UPF0449 UDPGP PF01704.13 XP_011275535.1 - 6.1e-46 156.7 0.0 8.2e-46 156.3 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 XP_011275535.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 MobA-like NTP transferase domain Beta_elim_lyase PF01212.16 XP_011275536.1 - 1.9e-75 253.6 0.0 2.3e-75 253.4 0.0 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 XP_011275536.1 - 2.5e-05 23.4 0.0 3.3e-05 23.0 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 XP_011275537.1 - 4.1e-75 252.6 0.0 4.9e-75 252.3 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 XP_011275537.1 - 5.6e-09 35.4 0.0 7.1e-09 35.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II fn3 PF00041.16 XP_011275538.1 - 0.00024 21.1 2.2 0.00053 20.0 0.0 2.5 2 0 0 2 2 2 1 Fibronectin type III domain Anp1 PF03452.9 XP_011275539.1 - 8.3e-119 395.6 0.0 1.4e-118 394.9 0.0 1.3 1 0 0 1 1 1 1 Anp1 MFS_1_like PF12832.2 XP_011275539.1 - 0.12 12.2 1.1 1.6 8.6 0.8 2.2 2 0 0 2 2 2 0 MFS_1 like family Beta_elim_lyase PF01212.16 XP_011275540.1 - 2.1e-71 240.4 0.0 2.7e-71 240.0 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase YL1_C PF08265.6 XP_011275541.1 - 4.5e-13 48.5 0.6 6.7e-13 47.9 0.4 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain IFRD PF05004.8 XP_011275542.1 - 1.6e-09 37.3 0.0 2.6e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) DUF4304 PF14137.1 XP_011275542.1 - 0.9 9.6 5.0 1.4 9.0 1.5 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4304) Sec23_trunk PF04811.10 XP_011275543.1 - 1.5e-67 227.5 0.0 2.1e-67 227.0 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 XP_011275543.1 - 1.2e-33 114.5 0.3 2.7e-33 113.4 0.2 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 XP_011275543.1 - 5.3e-32 110.2 0.0 9.9e-32 109.3 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 XP_011275543.1 - 1.9e-13 49.7 6.4 3.4e-13 48.8 4.5 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 XP_011275543.1 - 2.7e-10 39.7 0.0 5.4e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat zf-MIZ PF02891.15 XP_011275543.1 - 0.12 11.8 2.0 0.24 10.9 1.4 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger YxiJ PF14176.1 XP_011275543.1 - 0.44 10.6 0.0 0.44 10.6 0.0 2.5 3 0 0 3 3 3 0 YxiJ-like protein ThiF PF00899.16 XP_011275544.1 - 9.2e-16 57.8 0.1 3.3e-15 56.0 0.1 2.0 1 1 1 2 2 2 1 ThiF family SbcD_C PF12320.3 XP_011275544.1 - 0.091 12.8 1.7 11 6.1 0.1 2.6 2 0 0 2 2 2 0 Type 5 capsule protein repressor C-terminal domain Hydrolase_3 PF08282.7 XP_011275544.1 - 0.096 12.2 5.5 0.18 11.3 3.8 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase HDA2-3 PF11496.3 XP_011275545.1 - 8.2e-68 228.3 0.9 8.2e-68 228.3 0.6 2.9 2 1 1 3 3 3 2 Class II histone deacetylase complex subunits 2 and 3 WD40 PF00400.27 XP_011275546.1 - 1.8e-44 148.0 8.9 2.8e-08 33.3 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.6 XP_011275546.1 - 8.2e-14 50.5 0.1 1.7e-13 49.5 0.1 1.6 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like eIF2A PF08662.6 XP_011275546.1 - 0.002 17.9 0.0 0.43 10.2 0.0 2.6 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Prenyltrans PF00432.16 XP_011275547.1 - 1.7e-61 203.4 4.6 3.9e-12 45.5 0.1 6.3 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 XP_011275547.1 - 8.7e-47 158.2 0.0 1e-18 67.7 0.0 3.9 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 XP_011275547.1 - 1e-11 44.7 0.0 3.4e-06 27.0 0.0 3.1 1 1 2 3 3 3 2 Prenyltransferase-like A2M_comp PF07678.9 XP_011275547.1 - 0.02 14.1 0.2 1.2 8.2 0.0 3.2 3 1 1 4 4 4 0 A-macroglobulin complement component DNA_pol_E_B PF04042.11 XP_011275548.1 - 4.7e-42 143.5 0.1 7.1e-42 143.0 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B FANCF PF11107.3 XP_011275548.1 - 0.09 12.0 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Fanconi anemia group F protein (FANCF) AHS2 PF02626.10 XP_011275548.1 - 0.1 11.9 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Allophanate hydrolase subunit 2 Nsp1_C PF05064.8 XP_011275549.1 - 0.038 13.6 1.6 0.054 13.1 0.1 1.9 2 0 0 2 2 2 0 Nsp1-like C-terminal region Uricase PF01014.13 XP_011275549.1 - 0.052 13.6 0.0 0.16 12.0 0.0 1.8 1 0 0 1 1 1 0 Uricase DUF972 PF06156.8 XP_011275549.1 - 0.43 10.9 2.0 2 8.8 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Tropomyosin_1 PF12718.2 XP_011275549.1 - 0.5 10.2 5.5 0.34 10.7 0.8 2.6 3 0 0 3 3 3 0 Tropomyosin like Bacillus_HBL PF05791.6 XP_011275549.1 - 0.91 8.8 6.1 2 7.7 0.1 2.9 3 0 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Allexi_40kDa PF05549.6 XP_011275549.1 - 1.8 7.8 9.4 4.4 6.5 0.2 2.7 2 1 1 3 3 3 0 Allexivirus 40kDa protein AAA PF00004.24 XP_011275550.1 - 8.2e-43 145.7 0.0 1.8e-42 144.6 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 XP_011275550.1 - 2.9e-30 103.9 0.1 4.8e-29 100.0 0.2 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 XP_011275550.1 - 5.3e-24 83.8 2.7 5.3e-24 83.8 1.9 2.7 4 0 0 4 4 3 1 MIT (microtubule interacting and transport) domain AAA_17 PF13207.1 XP_011275550.1 - 2.7e-06 28.1 0.4 2.2e-05 25.2 0.0 2.7 3 1 0 3 3 1 1 AAA domain RuvB_N PF05496.7 XP_011275550.1 - 9.3e-06 24.8 0.0 1.6e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 XP_011275550.1 - 9.5e-06 25.7 0.1 0.0015 18.6 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 XP_011275550.1 - 1.6e-05 24.6 0.0 9.8e-05 22.1 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 XP_011275550.1 - 2.4e-05 24.4 0.1 0.0082 16.3 0.0 3.1 3 0 0 3 3 3 1 RNA helicase IstB_IS21 PF01695.12 XP_011275550.1 - 2.6e-05 23.7 0.0 6.8e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 XP_011275550.1 - 3.1e-05 23.8 0.0 0.00011 22.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 XP_011275550.1 - 0.00015 21.7 0.0 0.0011 19.0 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 XP_011275550.1 - 0.00024 20.5 0.1 0.11 11.8 0.1 2.3 1 1 1 2 2 2 2 AAA domain AAA_33 PF13671.1 XP_011275550.1 - 0.00043 20.1 0.0 0.0011 18.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 XP_011275550.1 - 0.00044 19.2 0.0 0.00082 18.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_2 PF07724.9 XP_011275550.1 - 0.00054 19.9 0.0 0.0026 17.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.8 XP_011275550.1 - 0.00089 18.0 0.0 0.0016 17.2 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_18 PF13238.1 XP_011275550.1 - 0.005 17.1 0.0 0.015 15.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain Torsin PF06309.6 XP_011275550.1 - 0.0076 16.1 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Torsin Zeta_toxin PF06414.7 XP_011275550.1 - 0.0091 15.1 0.1 0.29 10.2 0.0 2.5 1 1 1 2 2 2 1 Zeta toxin AAA_24 PF13479.1 XP_011275550.1 - 0.021 14.4 0.0 0.04 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 XP_011275550.1 - 0.023 14.4 0.0 0.066 12.9 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Mg_chelatase PF01078.16 XP_011275550.1 - 0.023 13.8 0.0 0.067 12.3 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI PhoH PF02562.11 XP_011275550.1 - 0.039 13.1 0.0 0.098 11.8 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.7 XP_011275550.1 - 0.043 13.4 0.0 0.58 9.7 0.0 2.2 1 1 1 2 2 2 0 NACHT domain KaiC PF06745.8 XP_011275550.1 - 0.059 12.4 0.0 6.3 5.8 0.0 2.4 1 1 1 2 2 2 0 KaiC Sigma54_activat PF00158.21 XP_011275550.1 - 0.079 12.4 0.0 0.35 10.3 0.0 2.2 1 1 1 2 2 2 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 XP_011275550.1 - 0.1 11.4 0.0 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_28 PF13521.1 XP_011275550.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 XP_011275550.1 - 0.12 12.0 1.3 1 9.0 0.0 2.6 2 1 1 3 3 3 0 Archaeal ATPase Pyridox_oxidase PF01243.15 XP_011275551.1 - 8.8e-11 41.6 0.0 1.4e-09 37.8 0.0 2.3 2 1 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Pyrid_oxidase_2 PF13883.1 XP_011275551.1 - 0.00091 19.0 0.0 0.0013 18.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase ORC4_C PF14629.1 XP_011275552.1 - 6.1e-30 104.1 2.8 4.5e-28 98.0 2.7 2.5 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 XP_011275552.1 - 7.5e-13 48.8 0.0 2.1e-12 47.3 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 XP_011275552.1 - 1.1e-08 35.0 1.4 1.1e-08 35.0 1.0 2.3 2 0 0 2 2 2 1 Archaeal ATPase AAA PF00004.24 XP_011275552.1 - 3.2e-07 30.5 0.7 6.2e-06 26.4 0.5 2.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 XP_011275552.1 - 6.4e-07 29.5 0.1 2e-06 27.9 0.1 1.8 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 XP_011275552.1 - 0.0085 15.7 0.1 0.016 14.8 0.1 1.5 1 0 0 1 1 1 1 NACHT domain MobB PF03205.9 XP_011275552.1 - 0.013 15.2 0.0 0.033 13.8 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 XP_011275552.1 - 0.024 13.5 0.1 0.042 12.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein MMR_HSR1 PF01926.18 XP_011275552.1 - 0.081 12.8 0.1 0.081 12.8 0.1 3.1 3 0 0 3 3 3 0 50S ribosome-binding GTPase AAA_33 PF13671.1 XP_011275552.1 - 0.12 12.2 0.1 4.4 7.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain RGS PF00615.14 XP_011275553.1 - 5.5e-18 65.1 5.6 8.2e-13 48.4 0.2 3.6 4 0 0 4 4 4 2 Regulator of G protein signaling domain DEP PF00610.16 XP_011275553.1 - 1.2e-10 40.9 0.0 1.2e-08 34.5 0.0 2.5 2 0 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) GTP_EFTU PF00009.22 XP_011275554.1 - 1.3e-38 132.3 0.3 2.8e-38 131.2 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 XP_011275554.1 - 2.3e-36 123.7 0.4 5e-36 122.6 0.3 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 XP_011275554.1 - 8.6e-12 45.0 1.0 2.5e-11 43.5 0.3 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 XP_011275554.1 - 0.0031 17.4 0.0 0.0094 15.8 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 XP_011275554.1 - 0.14 11.9 3.3 0.35 10.6 0.1 2.9 2 1 0 2 2 2 0 Dynamin family Kinetochor_Ybp2 PF08568.5 XP_011275555.1 - 9.2e-100 334.7 31.2 1.1e-99 334.4 21.6 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin HUN PF08729.5 XP_011275556.1 - 7.4e-13 48.1 0.2 7.4e-13 48.1 0.2 3.8 3 0 0 3 3 3 1 HPC2 and ubinuclein domain BCDHK_Adom3 PF10436.4 XP_011275557.1 - 1e-36 125.9 0.1 2.1e-36 124.9 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 XP_011275557.1 - 3.9e-10 39.4 0.0 1.2e-08 34.6 0.0 2.3 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 XP_011275557.1 - 0.00034 20.2 0.0 0.00065 19.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase UQ_con PF00179.21 XP_011275558.1 - 9.9e-49 164.3 0.0 1.2e-48 164.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 XP_011275558.1 - 2.6e-06 27.2 0.0 3.3e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 XP_011275558.1 - 0.0052 16.6 0.1 0.009 15.9 0.1 1.6 1 1 0 1 1 1 1 RWD domain COX4 PF02936.9 XP_011275559.1 - 4.3e-06 26.5 0.2 4.3e-06 26.5 0.2 2.1 2 1 1 3 3 3 1 Cytochrome c oxidase subunit IV EDR1 PF14381.1 XP_011275559.1 - 0.06 12.9 0.2 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 Fcf1 PF04900.7 XP_011275560.1 - 3.3e-21 75.2 1.8 3.4e-21 75.2 0.0 1.9 2 0 0 2 2 2 1 Fcf1 Menin PF05053.8 XP_011275560.1 - 4 5.4 9.6 5.4 5.0 6.7 1.2 1 0 0 1 1 1 0 Menin Ribosomal_60s PF00428.14 XP_011275561.1 - 6.6e-29 100.1 12.3 7.6e-29 99.9 8.5 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF1308 PF07000.6 XP_011275561.1 - 0.034 12.8 0.1 0.034 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1308) FTA4 PF13093.1 XP_011275562.1 - 6.4e-09 35.5 13.3 0.00015 21.3 7.3 2.1 1 1 1 2 2 2 2 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 IFP_35_N PF07334.8 XP_011275562.1 - 4.6 7.2 11.1 6.3 6.8 0.9 2.7 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Fzo_mitofusin PF04799.8 XP_011275562.1 - 5.4 6.3 11.4 3.1 7.1 1.1 2.2 2 0 0 2 2 2 0 fzo-like conserved region DUF722 PF05263.6 XP_011275562.1 - 8.5 6.5 13.2 6.4 6.9 1.0 3.0 1 1 1 3 3 3 0 Protein of unknown function (DUF722) Nuc_recep-AF1 PF11825.3 XP_011275563.1 - 0.0033 17.3 0.8 0.0033 17.3 0.5 1.7 2 0 0 2 2 2 1 Nuclear/hormone receptor activator site AF-1 GTP_EFTU PF00009.22 XP_011275564.1 - 1.7e-63 213.4 0.1 2.4e-63 212.9 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 XP_011275564.1 - 4.1e-33 113.4 0.0 1.1e-32 112.1 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 XP_011275564.1 - 4.1e-21 74.6 0.0 9.1e-21 73.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 XP_011275564.1 - 2.6e-13 49.8 0.9 1.6e-12 47.3 0.0 2.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.1 XP_011275564.1 - 5.2e-13 48.6 0.0 1.7e-12 47.0 0.0 1.8 2 0 0 2 2 2 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 XP_011275564.1 - 1.1e-05 25.3 0.1 2.4e-05 24.2 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 XP_011275564.1 - 0.061 12.8 0.5 0.29 10.6 0.2 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SUKH-4 PF14435.1 XP_011275564.1 - 0.076 12.7 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 SUKH-4 immunity protein Miro PF08477.8 XP_011275564.1 - 0.082 13.4 0.3 0.37 11.2 0.1 2.2 1 1 1 2 2 2 0 Miro-like protein PX PF00787.19 XP_011275565.1 - 6.9e-11 41.9 1.7 1.5e-10 40.8 1.2 1.6 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 XP_011275565.1 - 2.1e-08 33.7 9.0 4e-08 32.8 6.3 1.4 1 0 0 1 1 1 1 Vps5 C terminal like RRM_6 PF14259.1 XP_011275567.1 - 1.2e-06 28.3 0.0 5.1e-06 26.3 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 XP_011275567.1 - 4.9e-05 23.0 0.0 0.00016 21.4 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 XP_011275567.1 - 0.0011 18.4 0.1 0.011 15.3 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.12 XP_011275567.1 - 0.0029 17.6 1.3 0.0051 16.8 0.0 2.1 2 0 0 2 2 2 1 PWI domain Hormone_1 PF00103.15 XP_011275567.1 - 0.0083 15.4 1.5 0.015 14.6 1.0 1.4 1 0 0 1 1 1 1 Somatotropin hormone family PurS PF02700.9 XP_011275567.1 - 0.086 12.8 0.5 0.62 10.0 0.0 2.3 2 0 0 2 2 2 0 Phosphoribosylformylglycinamidine (FGAM) synthase Seryl_tRNA_N PF02403.17 XP_011275567.1 - 6.2 6.8 14.4 3.8 7.5 6.9 2.7 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain HAD PF12710.2 XP_011275568.1 - 9.6e-12 45.4 0.2 1.7e-11 44.6 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 XP_011275568.1 - 5.4e-11 42.5 4.5 4e-09 36.4 0.0 3.5 3 1 1 4 4 4 2 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 XP_011275568.1 - 5.2e-08 33.5 0.6 2e-06 28.3 0.4 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 XP_011275568.1 - 0.0015 18.7 0.0 0.0034 17.6 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 XP_011275568.1 - 0.0018 17.5 0.1 0.032 13.3 0.0 2.5 3 0 0 3 3 3 1 Putative Phosphatase DUF705 PF05152.7 XP_011275568.1 - 0.035 13.0 0.8 0.25 10.2 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF705) S6PP PF05116.8 XP_011275568.1 - 0.078 12.2 0.1 0.31 10.3 0.0 1.9 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase Aminotran_4 PF01063.14 XP_011275569.1 - 1.7e-30 106.1 0.0 4e-30 104.9 0.0 1.7 1 0 0 1 1 1 1 Aminotransferase class IV Rap1-DNA-bind PF09197.5 XP_011275569.1 - 9.8e-26 90.3 6.6 6.9e-21 74.7 0.0 4.0 3 2 0 3 3 3 2 Rap1, DNA-binding Rap1_C PF11626.3 XP_011275569.1 - 7.3e-12 45.0 0.0 6.8e-11 41.9 0.0 2.6 2 0 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.6 XP_011275569.1 - 1.1e-09 37.9 1.9 2.4e-05 24.0 0.0 3.5 2 1 0 2 2 2 2 Rap1 Myb domain Myb_DNA-binding PF00249.26 XP_011275569.1 - 2.2e-08 34.0 0.0 2e-07 30.9 0.0 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 XP_011275569.1 - 5.8e-06 26.3 0.1 0.00023 21.1 0.0 2.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain BRCT PF00533.21 XP_011275569.1 - 0.039 14.0 0.0 0.13 12.4 0.0 1.9 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Thioredoxin PF00085.15 XP_011275570.1 - 5.4e-31 106.3 0.3 5.9e-31 106.2 0.2 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 XP_011275570.1 - 8.5e-08 32.3 0.3 2.8e-06 27.5 0.2 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 XP_011275570.1 - 5.3e-07 29.6 0.1 2.8e-06 27.3 0.0 1.9 1 1 1 2 2 2 1 Thioredoxin-like Redoxin PF08534.5 XP_011275570.1 - 2.9e-06 26.9 0.3 3.6e-05 23.3 0.1 2.0 1 1 1 2 2 2 1 Redoxin Thioredoxin_9 PF14595.1 XP_011275570.1 - 1.5e-05 24.5 0.1 1.7e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.16 XP_011275570.1 - 5.7e-05 22.7 0.1 6.8e-05 22.5 0.1 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.1 XP_011275570.1 - 0.0027 17.6 0.2 0.0048 16.8 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like Glutaredoxin PF00462.19 XP_011275570.1 - 0.0077 16.2 0.1 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Phosducin PF02114.11 XP_011275570.1 - 0.017 13.8 0.0 0.018 13.7 0.0 1.0 1 0 0 1 1 1 0 Phosducin DIM1 PF02966.11 XP_011275570.1 - 0.034 13.6 0.2 0.036 13.5 0.1 1.1 1 0 0 1 1 1 0 Mitosis protein DIM1 NADH_u_ox_C PF12853.2 XP_011275571.1 - 2.2e-36 123.4 0.0 3.2e-36 122.9 0.0 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit NADH-u_ox-rdase PF10785.4 XP_011275571.1 - 1.4e-14 54.1 0.1 2.1e-14 53.5 0.1 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit ETF PF01012.16 XP_011275572.1 - 1.4e-22 80.2 0.0 1.9e-22 79.7 0.0 1.2 1 0 0 1 1 1 1 Electron transfer flavoprotein domain AAA_17 PF13207.1 XP_011275573.1 - 1.9e-06 28.6 1.1 4.9e-05 24.1 0.7 2.2 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 XP_011275573.1 - 9.3e-05 21.6 0.0 0.00015 20.9 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin PRK PF00485.13 XP_011275573.1 - 0.00028 20.5 0.1 0.0052 16.3 0.0 2.1 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.1 XP_011275573.1 - 0.00045 20.1 0.0 0.00072 19.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain Torsin PF06309.6 XP_011275573.1 - 0.0013 18.6 0.0 0.0026 17.6 0.0 1.5 1 0 0 1 1 1 1 Torsin RNA_helicase PF00910.17 XP_011275573.1 - 0.0021 18.2 0.1 0.0067 16.5 0.0 1.9 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.1 XP_011275573.1 - 0.0022 17.9 0.7 0.0067 16.3 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 XP_011275573.1 - 0.0082 16.4 0.8 0.029 14.6 0.2 2.3 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 XP_011275573.1 - 0.0095 15.9 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain PhoH PF02562.11 XP_011275573.1 - 0.027 13.6 0.0 0.046 12.9 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein KAP_NTPase PF07693.9 XP_011275573.1 - 0.028 13.4 0.0 0.039 12.9 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain Adeno_IVa2 PF02456.10 XP_011275573.1 - 0.083 11.5 0.1 0.24 9.9 0.0 1.7 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_25 PF13481.1 XP_011275573.1 - 0.084 12.2 0.0 0.19 11.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 XP_011275573.1 - 2.3 8.5 7.2 4.4 7.5 5.0 1.6 1 1 0 1 1 1 0 AAA domain Mer2 PF09074.5 XP_011275574.1 - 2.5e-06 27.5 24.7 2.5e-06 27.5 17.2 3.2 1 1 2 3 3 3 1 Mer2 Pkinase PF00069.20 XP_011275575.1 - 3.3e-69 232.9 0.0 4.3e-69 232.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011275575.1 - 5.7e-34 117.3 0.0 8.2e-34 116.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 XP_011275575.1 - 2.3e-14 53.2 0.7 2.3e-14 53.2 0.5 1.9 2 0 0 2 2 2 1 FHA domain Calpain_III PF01067.17 XP_011275575.1 - 0.024 14.2 0.3 0.092 12.3 0.1 2.0 2 0 0 2 2 2 0 Calpain large subunit, domain III Kdo PF06293.9 XP_011275575.1 - 0.044 12.8 0.0 0.075 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ATG16 PF08614.6 XP_011275577.1 - 7.4e-25 87.9 20.9 1.3e-19 70.7 10.4 2.0 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) KLRAQ PF10205.4 XP_011275577.1 - 0.00032 20.6 6.9 0.00032 20.6 4.8 2.1 1 1 1 2 2 2 1 Predicted coiled-coil domain-containing protein GAS PF13851.1 XP_011275577.1 - 0.098 11.8 23.1 0.33 10.1 3.6 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding HALZ PF02183.13 XP_011275577.1 - 0.11 12.2 0.7 0.11 12.2 0.5 4.1 2 2 2 4 4 4 0 Homeobox associated leucine zipper Ribosomal_S30AE PF02482.14 XP_011275577.1 - 0.19 12.1 5.7 0.068 13.6 1.3 2.0 2 1 0 2 2 2 0 Sigma 54 modulation protein / S30EA ribosomal protein IncA PF04156.9 XP_011275577.1 - 0.26 10.8 19.5 0.31 10.5 8.5 2.1 1 1 1 2 2 2 0 IncA protein DUF2205 PF10224.4 XP_011275577.1 - 0.37 10.4 17.2 0.11 12.0 1.6 3.6 1 1 2 3 3 3 0 Predicted coiled-coil protein (DUF2205) Mto2_bdg PF12808.2 XP_011275577.1 - 0.43 10.7 14.2 0.62 10.2 1.3 3.5 2 1 1 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DivIC PF04977.10 XP_011275577.1 - 0.49 9.9 24.4 0.37 10.3 2.8 3.9 1 1 3 4 4 4 0 Septum formation initiator SidE PF12252.3 XP_011275577.1 - 0.52 7.5 10.8 0.64 7.2 7.5 1.0 1 0 0 1 1 1 0 Dot/Icm substrate protein CENP-F_leu_zip PF10473.4 XP_011275577.1 - 0.52 10.1 22.1 1.3 8.9 15.4 1.6 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 KapB PF08810.5 XP_011275577.1 - 0.57 10.2 5.3 0.53 10.3 2.3 1.9 1 1 1 2 2 2 0 Kinase associated protein B ADIP PF11559.3 XP_011275577.1 - 0.79 9.6 21.7 0.27 11.1 8.6 2.3 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Herpes_BLRF2 PF05812.7 XP_011275577.1 - 0.95 9.2 19.8 6.1 6.6 6.8 2.6 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein NYD-SP28_assoc PF14775.1 XP_011275577.1 - 1 9.1 14.9 13 5.5 0.1 4.1 2 1 1 3 3 3 0 Sperm tail C-terminal domain Nup54 PF13874.1 XP_011275577.1 - 1 9.0 9.0 0.093 12.3 0.5 2.3 1 1 2 3 3 3 0 Nucleoporin complex subunit 54 DUF883 PF05957.8 XP_011275577.1 - 1.1 9.7 7.4 8.8 6.8 2.0 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Laminin_II PF06009.7 XP_011275577.1 - 1.1 8.9 17.5 0.1 12.3 4.7 2.4 1 1 2 3 3 3 0 Laminin Domain II DUF1049 PF06305.6 XP_011275577.1 - 1.2 8.6 7.8 1.5 8.3 0.4 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1049) DUF972 PF06156.8 XP_011275577.1 - 1.8 8.9 20.3 1.3e+04 -3.5 13.9 2.9 1 1 0 1 1 0 0 Protein of unknown function (DUF972) DUF1640 PF07798.6 XP_011275577.1 - 2.2 8.2 15.3 1.2 9.1 5.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) DUF3573 PF12097.3 XP_011275577.1 - 2.3 6.7 7.8 2.7 6.5 5.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) TPR_MLP1_2 PF07926.7 XP_011275577.1 - 2.4 7.9 24.7 2.6 7.7 14.3 2.5 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein APG6 PF04111.7 XP_011275577.1 - 2.5 7.0 21.3 5.1 6.0 14.4 1.7 1 1 0 1 1 1 0 Autophagy protein Apg6 Tropomyosin_1 PF12718.2 XP_011275577.1 - 2.7 7.8 24.0 3.6 7.4 16.6 1.2 1 0 0 1 1 1 0 Tropomyosin like DUF730 PF05325.6 XP_011275577.1 - 3 7.6 8.9 3 7.6 1.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF730) Chorismate_synt PF01264.16 XP_011275578.1 - 2.6e-133 443.8 0.0 3e-133 443.6 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase Hormone_4 PF00220.12 XP_011275578.1 - 0.06 13.0 3.5 0.15 11.8 2.4 1.7 1 0 0 1 1 1 0 Neurohypophysial hormones, N-terminal Domain PEX11 PF05648.9 XP_011275579.1 - 8.5e-65 218.1 2.0 9.5e-65 217.9 1.4 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Histone PF00125.19 XP_011275580.1 - 6e-22 77.5 0.1 8.4e-22 77.0 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 XP_011275580.1 - 0.00091 19.2 0.0 0.0013 18.7 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone XRN_N PF03159.13 XP_011275580.1 - 0.058 12.7 0.1 0.089 12.1 0.1 1.2 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus Cpn60_TCP1 PF00118.19 XP_011275581.1 - 3.6e-118 395.2 9.6 4.1e-118 395.0 6.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Rrf2 PF02082.15 XP_011275581.1 - 0.022 14.8 0.1 0.059 13.4 0.1 1.7 1 0 0 1 1 1 0 Transcriptional regulator NPR2 PF06218.6 XP_011275582.1 - 1.3e-167 557.8 7.0 1.3e-167 557.8 4.8 2.0 2 1 0 2 2 2 1 Nitrogen permease regulator 2 NPR3 PF03666.8 XP_011275582.1 - 5.6e-05 21.8 0.7 8.6e-05 21.2 0.5 4.2 3 3 2 5 5 5 2 Nitrogen Permease regulator of amino acid transport activity 3 Nop14 PF04147.7 XP_011275582.1 - 7.4e-05 20.8 9.1 0.00012 20.2 6.3 1.2 1 0 0 1 1 1 1 Nop14-like family Sigma70_ner PF04546.8 XP_011275582.1 - 0.00058 19.5 7.7 0.0013 18.3 5.4 1.5 1 0 0 1 1 1 1 Sigma-70, non-essential region Kinesin PF00225.18 XP_011275583.1 - 1.4e-101 339.5 5.6 1.4e-101 339.5 3.9 3.1 3 0 0 3 3 3 1 Kinesin motor domain Cortex-I_coil PF09304.5 XP_011275583.1 - 0.0021 18.0 9.9 0.0021 18.0 6.8 4.9 3 2 3 7 7 7 1 Cortexillin I, coiled coil DUF4042 PF13251.1 XP_011275583.1 - 0.045 13.2 0.3 0.14 11.5 0.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4042) DUF2209 PF09974.4 XP_011275583.1 - 0.28 11.2 7.4 0.47 10.5 0.3 3.5 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2209) DUF4337 PF14235.1 XP_011275583.1 - 1.7 8.4 7.9 2 8.2 2.8 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) CBS PF00571.23 XP_011275584.1 - 9.1e-21 73.3 0.1 0.00039 20.1 0.2 5.0 4 1 0 4 4 4 4 CBS domain E1-E2_ATPase PF00122.15 XP_011275585.1 - 2.6e-50 170.6 0.3 1.5e-49 168.1 0.0 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 XP_011275585.1 - 1.8e-37 128.6 6.9 1.8e-37 128.6 4.8 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 XP_011275585.1 - 2.4e-28 100.0 0.0 1.6e-27 97.3 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 XP_011275585.1 - 1.9e-17 62.9 0.1 1.6e-16 60.0 0.0 2.3 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 XP_011275585.1 - 3.5e-17 63.1 0.0 1.1e-16 61.5 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 XP_011275585.1 - 6.9e-14 51.0 0.0 2.4e-13 49.3 0.0 2.0 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 XP_011275585.1 - 0.00057 19.5 0.0 0.0027 17.3 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase PHP PF02811.14 XP_011275586.1 - 3.9e-15 56.0 1.3 9.2e-15 54.8 0.9 1.6 1 1 0 1 1 1 1 PHP domain CAT_RBD PF03123.10 XP_011275586.1 - 0.091 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 CAT RNA binding domain Phosphodiest PF01663.17 XP_011275588.1 - 8.2e-79 265.5 0.7 1.1e-78 265.1 0.5 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase TPP_enzyme_N PF02776.13 XP_011275589.1 - 5.3e-46 156.2 0.0 2.3e-45 154.1 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 XP_011275589.1 - 2.5e-31 108.2 0.0 4.9e-31 107.2 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 XP_011275589.1 - 8.9e-26 90.2 0.0 1.6e-25 89.4 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain tRNA-synt_2 PF00152.15 XP_011275590.1 - 1.2e-73 247.8 0.1 1.6e-73 247.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 XP_011275590.1 - 2.4e-07 30.5 0.0 4.4e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain zf-Nse PF11789.3 XP_011275591.1 - 1.8e-14 52.9 0.1 2.9e-14 52.3 0.1 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 XP_011275591.1 - 4.7e-05 23.0 0.5 0.00016 21.3 0.3 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-MIZ PF02891.15 XP_011275591.1 - 0.015 14.8 0.3 0.028 13.9 0.2 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-C3HC4_4 PF15227.1 XP_011275591.1 - 0.02 14.7 0.9 0.036 13.9 0.6 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING U-box PF04564.10 XP_011275591.1 - 0.043 13.7 0.1 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 U-box domain Bromodomain PF00439.20 XP_011275592.1 - 3e-26 91.1 0.8 7.5e-26 89.8 0.3 1.9 2 0 0 2 2 2 1 Bromodomain zf-Tim10_DDP PF02953.10 XP_011275593.1 - 4.3e-20 70.7 4.1 5.6e-20 70.4 2.7 1.3 1 1 0 1 1 1 1 Tim10/DDP family zinc finger Mmp37 PF09139.6 XP_011275593.1 - 0.021 13.8 0.3 0.021 13.8 0.2 1.0 1 0 0 1 1 1 0 Mitochondrial matrix Mmp37 CARM1 PF11531.3 XP_011275593.1 - 0.046 13.4 0.6 0.067 12.9 0.5 1.6 1 1 0 1 1 1 0 Coactivator-associated arginine methyltransferase 1 N terminal DUF740 PF05340.7 XP_011275593.1 - 0.077 11.3 0.4 0.071 11.4 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF740) Vicilin_N PF04702.7 XP_011275593.1 - 1.4 8.5 6.1 1.7 8.2 4.2 1.2 1 0 0 1 1 1 0 Vicilin N terminal region OMPdecase PF00215.19 XP_011275594.1 - 3.6e-77 258.7 0.0 4.2e-77 258.5 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Mito_carr PF00153.22 XP_011275595.1 - 1.1e-11 44.3 0.6 2.5e-08 33.4 0.0 3.6 3 1 0 3 3 3 2 Mitochondrial carrier protein SQS_PSY PF00494.14 XP_011275596.1 - 2e-19 69.9 0.0 2.6e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase Pro_isomerase PF00160.16 XP_011275597.1 - 1.8e-40 138.6 0.4 3.3e-40 137.8 0.3 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 XP_011275597.1 - 9.1e-14 50.8 2.9 2.8e-08 33.2 0.2 2.5 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 XP_011275597.1 - 1.2e-11 43.7 13.0 1.4e-05 24.4 1.2 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 XP_011275597.1 - 1.1e-10 40.5 8.6 0.0011 18.6 0.5 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 XP_011275597.1 - 6.4e-07 29.2 2.7 0.00075 19.3 0.6 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 XP_011275597.1 - 0.00081 19.4 7.4 0.0032 17.5 5.2 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.13 XP_011275597.1 - 0.0014 18.4 5.5 0.17 11.8 0.1 3.0 2 1 0 2 2 2 2 MIT (microtubule interacting and transport) domain TPR_8 PF13181.1 XP_011275597.1 - 0.0065 16.1 14.0 0.28 11.0 1.5 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 XP_011275597.1 - 0.0071 16.9 0.4 4.6 8.0 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 XP_011275597.1 - 0.017 14.8 1.3 3.1 7.8 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 XP_011275597.1 - 0.074 13.4 0.6 0.84 10.0 0.4 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 XP_011275597.1 - 0.47 11.0 4.0 58 4.4 0.1 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Rav1p_C PF12234.3 XP_011275598.1 - 1.5e-233 776.5 11.0 2.1e-233 776.1 7.6 1.1 1 0 0 1 1 1 1 RAVE protein 1 C terminal WD40 PF00400.27 XP_011275598.1 - 0.00094 18.9 2.5 0.63 10.0 0.0 3.9 5 0 0 5 5 5 2 WD domain, G-beta repeat Pet191_N PF10203.4 XP_011275599.1 - 4.8e-21 74.5 1.1 6.8e-21 74.0 0.7 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Pyridoxal_deC PF00282.14 XP_011275600.1 - 7e-76 255.0 0.0 8.4e-76 254.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 XP_011275600.1 - 3.9e-06 26.2 0.0 4.8e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 XP_011275600.1 - 0.00014 20.7 0.0 0.00019 20.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V SLA_LP_auto_ag PF05889.8 XP_011275600.1 - 0.035 12.5 0.0 0.051 12.0 0.0 1.2 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) LPP20 PF02169.11 XP_011275601.1 - 3.9 7.6 6.8 4.9 7.3 4.7 1.2 1 0 0 1 1 1 0 LPP20 lipoprotein SNF2_N PF00176.18 XP_011275602.1 - 4.8e-68 229.1 0.0 4.8e-68 229.1 0.0 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 XP_011275602.1 - 2.1e-13 49.8 0.0 6.9e-13 48.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ProRS-C_1 PF09180.6 XP_011275603.1 - 1.4e-24 85.8 0.6 3.7e-24 84.4 0.4 1.8 2 0 0 2 2 2 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.20 XP_011275603.1 - 3.9e-21 75.3 0.0 6.2e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 XP_011275603.1 - 8.8e-19 67.2 0.0 1.9e-18 66.1 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA_edit PF04073.10 XP_011275603.1 - 2.1e-06 27.6 0.1 4.2e-06 26.6 0.1 1.4 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain tRNA-synt_2 PF00152.15 XP_011275604.1 - 2.6e-71 240.1 0.0 4e-71 239.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 XP_011275604.1 - 1.5e-11 43.9 0.1 3.3e-11 42.8 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Ins134_P3_kin PF05770.6 XP_011275604.1 - 0.04 12.9 0.0 0.07 12.1 0.0 1.3 1 0 0 1 1 1 0 Inositol 1, 3, 4-trisphosphate 5/6-kinase Lyase_1 PF00206.15 XP_011275605.1 - 2.3e-97 325.9 0.0 3.9e-97 325.2 0.0 1.3 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 XP_011275605.1 - 2.7e-26 91.4 0.0 5.3e-26 90.4 0.0 1.5 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal DUF1776 PF08643.5 XP_011275606.1 - 1.4e-59 201.7 2.6 7.9e-51 172.9 1.8 2.1 1 1 1 2 2 2 2 Fungal family of unknown function (DUF1776) DUF500 PF04366.7 XP_011275607.1 - 6.6e-46 154.8 0.3 1.3e-45 153.8 0.2 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_1 PF00018.23 XP_011275607.1 - 2.1e-17 62.2 0.1 4.4e-17 61.1 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 XP_011275607.1 - 1.6e-13 49.8 0.5 2.8e-13 49.1 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 XP_011275607.1 - 1.6e-13 49.9 0.1 4e-13 48.7 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain RRM_1 PF00076.17 XP_011275608.1 - 4.2e-41 138.4 7.2 1.8e-13 49.8 0.0 4.8 4 1 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 XP_011275608.1 - 6.4e-29 99.7 0.6 1.5e-09 37.6 0.0 4.8 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 XP_011275608.1 - 1.6e-21 75.8 3.4 8.3e-06 25.5 0.1 4.8 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 XP_011275608.1 - 0.0055 16.5 1.1 3.3 7.6 0.1 4.2 4 0 0 4 4 4 1 RNA binding motif Nup35_RRM_2 PF14605.1 XP_011275608.1 - 0.01 15.5 0.3 17 5.3 0.0 4.1 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif Pyr_redox_2 PF07992.9 XP_011275609.1 - 1.2e-22 80.8 0.0 8e-22 78.1 0.0 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 XP_011275609.1 - 4.4e-14 52.6 0.0 7.2e-11 42.3 0.0 2.9 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 XP_011275609.1 - 0.096 12.7 0.0 6.2 6.8 0.0 3.5 3 1 1 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase EAP30 PF04157.11 XP_011275610.1 - 4.9e-37 127.2 0.5 7.6e-37 126.6 0.3 1.3 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 XP_011275610.1 - 5.4e-31 106.2 1.6 7.8e-31 105.7 0.2 2.0 2 0 0 2 2 2 1 Vacuolar protein sorting protein 36 Vps36 Elf1 PF05129.8 XP_011275610.1 - 0.0018 17.9 0.5 0.0018 17.9 0.3 2.2 2 0 0 2 2 2 1 Transcription elongation factor Elf1 like zf-RanBP PF00641.13 XP_011275610.1 - 0.021 13.9 14.8 0.026 13.6 0.3 2.9 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others GRAM PF02893.15 XP_011275610.1 - 0.03 13.8 0.0 0.099 12.1 0.0 1.9 1 0 0 1 1 1 0 GRAM domain DZR PF12773.2 XP_011275610.1 - 0.037 13.8 0.6 0.037 13.8 0.4 2.4 1 1 2 3 3 3 0 Double zinc ribbon zf-ribbon_3 PF13248.1 XP_011275610.1 - 0.053 12.7 4.2 1.3 8.2 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-Sec23_Sec24 PF04810.10 XP_011275610.1 - 0.062 12.8 7.2 0.17 11.5 0.2 2.7 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf-piccolo PF05715.8 XP_011275610.1 - 3 7.9 9.2 0.17 11.9 0.9 2.7 3 0 0 3 3 3 0 Piccolo Zn-finger Mo25 PF08569.6 XP_011275611.1 - 3.7e-122 407.5 12.9 4.2e-122 407.3 9.0 1.0 1 0 0 1 1 1 1 Mo25-like DHDPS PF00701.17 XP_011275612.1 - 1e-34 119.4 0.0 1.3e-34 119.1 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Peripla_BP_1 PF00532.16 XP_011275612.1 - 0.061 12.5 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Periplasmic binding proteins and sugar binding domain of LacI family Aminotran_4 PF01063.14 XP_011275613.1 - 1.6e-28 99.7 0.0 2.1e-28 99.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV 5-FTHF_cyc-lig PF01812.15 XP_011275614.1 - 3.4e-30 105.2 0.0 4.4e-30 104.8 0.0 1.1 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family SET PF00856.23 XP_011275616.1 - 7.1e-11 42.6 0.4 1e-08 35.6 0.1 3.0 4 0 0 4 4 4 2 SET domain Ecl1 PF12855.2 XP_011275616.1 - 0.16 11.3 4.7 0.43 9.8 3.3 1.8 1 0 0 1 1 1 0 Life-span regulatory factor HSF_DNA-bind PF00447.12 XP_011275617.1 - 4.7e-36 123.1 3.1 4.7e-36 123.1 2.2 2.3 2 0 0 2 2 2 1 HSF-type DNA-binding Response_reg PF00072.19 XP_011275617.1 - 2.4e-25 88.7 0.1 4.7e-25 87.7 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Pkinase PF00069.20 XP_011275618.1 - 8.7e-69 231.5 0.0 1.5e-68 230.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011275618.1 - 2e-28 99.1 0.0 3.4e-28 98.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 XP_011275618.1 - 4.1e-13 49.6 3.6 4.1e-13 49.6 2.5 2.7 3 0 0 3 3 3 1 Protein kinase C terminal domain Kinase-like PF14531.1 XP_011275618.1 - 2.8e-09 36.3 0.0 7.2e-09 35.0 0.0 1.7 2 0 0 2 2 2 1 Kinase-like C2 PF00168.25 XP_011275618.1 - 1.7e-07 31.0 0.0 1.3e-06 28.1 0.0 2.4 1 1 0 1 1 1 1 C2 domain APH PF01636.18 XP_011275618.1 - 0.0094 15.7 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 XP_011275618.1 - 0.045 12.7 0.0 0.11 11.6 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Tim17 PF02466.14 XP_011275619.1 - 2.1e-08 34.2 2.5 3.4e-08 33.5 1.5 1.5 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Gly-zipper_OmpA PF13436.1 XP_011275619.1 - 0.24 11.0 5.7 0.38 10.4 0.7 2.3 1 1 1 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain MFS_1 PF07690.11 XP_011275620.1 - 3.6e-35 121.3 42.0 4.2e-34 117.8 20.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 XP_011275620.1 - 2.5e-11 42.8 28.6 5.5e-09 35.1 19.8 2.9 1 1 0 1 1 1 1 Sugar (and other) transporter Metallophos PF00149.23 XP_011275621.1 - 8.9e-10 38.2 6.7 2e-09 37.1 4.6 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ribosomal_S4e PF00900.15 XP_011275622.1 - 4.3e-32 109.5 0.3 5.5e-31 106.0 0.1 2.1 2 0 0 2 2 2 1 Ribosomal family S4e RS4NT PF08071.7 XP_011275622.1 - 1.1e-20 73.1 4.6 2.4e-20 72.1 3.2 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 XP_011275622.1 - 3.8e-08 32.6 0.0 7.9e-08 31.6 0.0 1.6 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 XP_011275622.1 - 4.6e-05 22.9 1.6 4.6e-05 22.9 1.1 3.0 4 0 0 4 4 4 1 KOW motif Glyco_hydro_47 PF01532.15 XP_011275623.1 - 1.1e-115 386.8 0.0 1.9e-115 386.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 TB2_DP1_HVA22 PF03134.14 XP_011275624.1 - 0.022 14.4 0.7 0.048 13.4 0.5 1.6 1 0 0 1 1 1 0 TB2/DP1, HVA22 family Mgm101p PF06420.7 XP_011275625.1 - 2.1e-87 290.8 0.0 3.3e-87 290.1 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 NUDIX PF00293.23 XP_011275626.1 - 0.00017 21.2 0.0 0.00029 20.5 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain PMT PF02366.13 XP_011275627.1 - 6.9e-81 271.2 20.1 6.9e-81 271.2 13.9 1.6 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 XP_011275627.1 - 3.6e-18 65.7 0.3 9.4e-18 64.4 0.1 1.7 1 1 1 2 2 2 1 MIR domain PMT_2 PF13231.1 XP_011275627.1 - 6.7e-08 32.5 15.7 6.7e-08 32.5 10.9 3.6 3 1 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase GAF_2 PF13185.1 XP_011275628.1 - 0.041 14.3 0.0 0.085 13.3 0.0 1.5 1 0 0 1 1 1 0 GAF domain TPR_8 PF13181.1 XP_011275628.1 - 5 7.1 8.0 3.3 7.7 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Chalcone PF02431.10 XP_011275629.1 - 1.8e-50 171.1 0.2 2.3e-50 170.7 0.1 1.1 1 0 0 1 1 1 1 Chalcone-flavanone isomerase Sulfatase PF00884.18 XP_011275630.1 - 4.3e-49 167.3 0.0 2.2e-48 165.0 0.0 1.8 1 1 0 1 1 1 1 Sulfatase DUF229 PF02995.12 XP_011275630.1 - 0.0006 18.3 0.0 0.00078 17.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase_C PF14707.1 XP_011275630.1 - 0.032 14.5 0.0 1 9.6 0.0 2.4 1 1 0 1 1 1 0 C-terminal region of aryl-sulfatase Phosphodiest PF01663.17 XP_011275630.1 - 0.037 13.3 0.1 0.12 11.6 0.0 1.5 1 1 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase RNase_T PF00929.19 XP_011275633.1 - 9.8e-14 51.9 0.0 2.4e-13 50.6 0.0 1.7 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 XP_011275633.1 - 0.021 14.3 0.1 0.051 13.0 0.1 1.8 1 1 0 1 1 1 0 3'-5' exonuclease BTK PF00779.14 XP_011275633.1 - 0.091 12.3 1.4 0.16 11.6 0.9 1.4 1 0 0 1 1 1 0 BTK motif Eapp_C PF10238.4 XP_011275634.1 - 0.69 9.8 3.7 0.82 9.5 0.1 2.0 2 0 0 2 2 2 0 E2F-associated phosphoprotein DUF2370 PF10176.4 XP_011275634.1 - 9.3 5.5 11.2 26 4.0 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2370) Exo_endo_phos PF03372.18 XP_011275635.1 - 1.7e-15 57.6 0.0 2.6e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 XP_011275635.1 - 8.1e-15 54.4 0.0 2.2e-13 49.8 0.0 2.6 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase zf-GRF PF06839.7 XP_011275635.1 - 5.7e-09 35.7 4.1 2e-08 34.0 2.8 2.0 1 0 0 1 1 1 1 GRF zinc finger DUF2316 PF10078.4 XP_011275636.1 - 0.0043 17.0 0.6 0.02 14.8 0.4 2.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2316) Adeno_E4 PF05385.6 XP_011275636.1 - 0.11 12.4 0.0 0.36 10.7 0.0 1.8 1 0 0 1 1 1 0 Mastadenovirus early E4 13 kDa protein Cpn60_TCP1 PF00118.19 XP_011275637.1 - 8.3e-134 446.8 14.3 1e-133 446.5 9.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Complex1_30kDa PF00329.14 XP_011275637.1 - 5.6e-36 122.8 0.0 1.1e-35 121.9 0.0 1.5 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Transposase_23 PF03017.9 XP_011275637.1 - 0.058 12.9 0.0 0.14 11.6 0.0 1.6 1 0 0 1 1 1 0 TNP1/EN/SPM transposase p450 PF00067.17 XP_011275638.1 - 9.6e-55 185.9 0.1 1.2e-54 185.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fer4 PF00037.22 XP_011275639.1 - 4.2e-14 51.4 16.3 1.6e-08 33.7 2.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 XP_011275639.1 - 1.3e-12 47.8 9.8 2.2e-12 47.1 6.8 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 XP_011275639.1 - 4.8e-11 43.2 9.9 6.9e-06 26.7 0.7 2.6 3 0 0 3 3 3 2 4Fe-4S double cluster binding domain Fer4_9 PF13187.1 XP_011275639.1 - 7.1e-11 42.2 7.9 1.4e-10 41.2 5.4 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 XP_011275639.1 - 1.8e-10 40.4 22.0 2.6e-08 33.5 8.4 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.1 XP_011275639.1 - 2.9e-09 36.6 21.9 7.3e-07 28.9 8.2 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.1 XP_011275639.1 - 9.3e-09 35.1 20.4 3e-06 27.1 7.7 2.0 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.2 XP_011275639.1 - 4.4e-08 32.5 14.2 0.00018 21.2 1.3 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 XP_011275639.1 - 1.8e-07 30.7 16.6 0.0012 18.6 3.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.2 XP_011275639.1 - 5e-07 29.5 11.3 0.00031 20.8 1.6 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.1 XP_011275639.1 - 1.3e-05 25.5 9.3 0.02 15.2 0.7 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.1 XP_011275639.1 - 1.9e-05 24.8 12.3 0.00012 22.3 8.1 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_13 PF13370.1 XP_011275639.1 - 0.0026 18.0 15.6 0.26 11.6 2.0 2.7 2 1 1 3 3 3 2 4Fe-4S single cluster domain Fer4_15 PF13459.1 XP_011275639.1 - 0.0043 17.5 13.4 0.27 11.8 1.2 2.9 2 1 0 2 2 2 2 4Fe-4S single cluster domain Fer4_3 PF12798.2 XP_011275639.1 - 0.0071 16.8 17.4 0.017 15.6 2.7 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.5 XP_011275639.1 - 0.11 12.6 4.4 0.15 12.1 0.1 2.3 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Beach PF02138.13 XP_011275640.1 - 1.4e-109 365.7 0.1 1.4e-109 365.7 0.1 2.1 2 0 0 2 2 2 1 Beige/BEACH domain PH_BEACH PF14844.1 XP_011275640.1 - 1.2e-10 41.1 0.0 3.9e-10 39.5 0.0 2.0 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.27 XP_011275640.1 - 0.002 17.9 0.0 2.5 8.0 0.0 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat Laminin_G_3 PF13385.1 XP_011275640.1 - 0.0045 17.2 0.0 0.012 15.8 0.0 1.7 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily MNSV_P7B PF06692.6 XP_011275640.1 - 0.16 11.7 3.2 0.27 11.0 0.6 2.7 2 0 0 2 2 2 0 Melon necrotic spot virus P7B protein TPT PF03151.11 XP_011275641.1 - 2.7e-30 105.0 0.5 2.7e-30 105.0 0.4 2.3 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 XP_011275641.1 - 0.46 10.5 29.9 0.22 11.5 5.9 3.1 3 2 0 3 3 3 0 EamA-like transporter family DUF2012 PF09430.5 XP_011275642.1 - 4.1e-11 42.7 0.0 6.4e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) CarboxypepD_reg PF13620.1 XP_011275642.1 - 0.00017 21.5 0.0 0.00029 20.8 0.0 1.3 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF4480 PF13715.1 XP_011275642.1 - 0.0043 17.0 0.0 0.0063 16.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4480) NDT80_PhoG PF05224.7 XP_011275642.1 - 0.058 13.3 0.1 0.095 12.6 0.0 1.3 1 1 0 1 1 1 0 NDT80 / PhoG like DNA-binding family DUF3445 PF11927.3 XP_011275643.1 - 2.6e-71 239.9 0.3 3.4e-71 239.5 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Ribosomal_S11 PF00411.14 XP_011275644.1 - 7.9e-40 135.4 0.7 9.4e-40 135.2 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 Ribosomal_S8 PF00410.14 XP_011275645.1 - 4.9e-26 91.0 0.0 6.7e-26 90.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Pkinase PF00069.20 XP_011275646.1 - 3.6e-50 170.5 0.0 6e-50 169.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011275646.1 - 4e-30 104.7 0.0 8e-30 103.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase DIE2_ALG10 PF04922.7 XP_011275647.1 - 0.012 14.6 1.7 0.014 14.4 1.2 1.1 1 0 0 1 1 1 0 DIE2/ALG10 family DUF2207 PF09972.4 XP_011275647.1 - 0.021 13.4 1.2 0.023 13.3 0.8 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Jiraiya PF15038.1 XP_011275647.1 - 0.022 14.1 0.1 0.029 13.7 0.1 1.2 1 0 0 1 1 1 0 Jiraiya DUF996 PF06195.8 XP_011275647.1 - 0.035 14.0 4.4 0.047 13.6 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF996) DUF912 PF06024.7 XP_011275647.1 - 0.035 14.1 1.7 0.044 13.8 0.8 1.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) SUR7 PF06687.7 XP_011275647.1 - 0.065 12.7 0.2 0.08 12.4 0.1 1.2 1 0 0 1 1 1 0 SUR7/PalI family Adeno_E3_CR2 PF02439.10 XP_011275647.1 - 4.3 6.9 6.3 9.2 5.8 4.4 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF3753 PF12575.3 XP_011275647.1 - 5.3 6.9 7.8 1.1 9.1 2.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3753) SSXT PF05030.7 XP_011275648.1 - 0.89 9.1 3.2 1 8.9 0.5 2.2 2 1 1 3 3 3 0 SSXT protein (N-terminal region) muHD PF10291.4 XP_011275649.1 - 5.5e-64 215.8 0.8 9.6e-64 215.0 0.6 1.4 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.18 XP_011275649.1 - 0.0007 19.7 0.1 0.0049 17.0 0.1 2.6 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DUF3150 PF11348.3 XP_011275649.1 - 0.087 11.9 2.8 0.87 8.6 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3150) SSB PF00436.20 XP_011275651.1 - 2.8e-20 72.0 0.0 3.8e-20 71.7 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family STE3 PF02076.10 XP_011275652.1 - 1.2e-87 293.5 23.2 1.5e-87 293.2 16.1 1.1 1 0 0 1 1 1 1 Pheromone A receptor DUF2401 PF10287.4 XP_011275653.1 - 2.8e-90 301.9 4.2 2.8e-90 301.9 2.9 2.0 2 0 0 2 2 2 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.4 XP_011275653.1 - 2.2e-23 82.1 0.0 5.4e-23 80.9 0.0 1.6 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) SRI PF08236.6 XP_011275654.1 - 3.3e-27 94.2 4.3 3.3e-27 94.2 2.9 3.1 1 1 2 3 3 3 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.23 XP_011275654.1 - 3.9e-21 76.0 0.2 3.9e-21 76.0 0.1 3.6 2 2 0 2 2 2 1 SET domain WW PF00397.21 XP_011275654.1 - 7.8e-09 35.2 2.4 1.6e-08 34.2 1.7 1.6 1 0 0 1 1 1 1 WW domain Med26 PF08711.6 XP_011275654.1 - 0.027 13.9 1.4 0.11 11.9 1.0 2.2 1 0 0 1 1 1 0 TFIIS helical bundle-like domain FAD_binding_8 PF08022.7 XP_011275656.1 - 9.2e-16 57.6 0.4 2.4e-15 56.2 0.2 1.8 2 0 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.14 XP_011275656.1 - 1.3e-13 51.1 7.9 1.3e-13 51.1 5.5 1.7 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 XP_011275656.1 - 4.3e-10 39.7 0.0 9.9e-05 22.2 0.1 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain Na_Ca_ex PF01699.19 XP_011275657.1 - 6.5e-34 116.5 30.0 2.5e-18 66.0 6.9 3.3 3 1 1 4 4 4 2 Sodium/calcium exchanger protein TRAM_LAG1_CLN8 PF03798.11 XP_011275658.1 - 5.7e-31 107.6 17.8 8.2e-31 107.0 12.4 1.2 1 0 0 1 1 1 1 TLC domain Flavokinase PF01687.12 XP_011275659.1 - 5.4e-26 90.9 0.1 8.6e-26 90.2 0.1 1.2 1 0 0 1 1 1 1 Riboflavin kinase GLE1 PF07817.8 XP_011275660.1 - 4e-82 275.0 0.1 4e-82 275.0 0.1 2.2 3 0 0 3 3 3 1 GLE1-like protein AvrE PF11725.3 XP_011275660.1 - 0.91 6.4 29.2 1.2 6.1 20.3 1.1 1 0 0 1 1 1 0 Pathogenicity factor KH_1 PF00013.24 XP_011275661.1 - 1.5e-09 37.3 4.9 1.5e-08 34.1 0.1 2.7 2 0 0 2 2 2 1 KH domain KH_3 PF13014.1 XP_011275661.1 - 2.7e-06 26.8 7.9 2.2e-05 23.9 0.9 3.4 3 0 0 3 3 3 2 KH domain IL6 PF00489.12 XP_011275661.1 - 0.0044 16.6 0.1 0.009 15.6 0.1 1.5 1 0 0 1 1 1 1 Interleukin-6/G-CSF/MGF family Complex1_LYR_1 PF13232.1 XP_011275661.1 - 0.014 15.5 0.4 0.029 14.5 0.3 1.5 1 0 0 1 1 1 0 Complex1_LYR-like Herpes_IE2_3 PF03361.9 XP_011275661.1 - 0.15 11.4 2.2 0.21 10.8 0.1 2.2 2 0 0 2 2 2 0 Herpes virus intermediate/early protein 2/3 Adaptin_N PF01602.15 XP_011275663.1 - 2.9e-103 345.9 6.3 4.1e-103 345.4 4.4 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 XP_011275663.1 - 7e-63 210.1 0.1 2.2e-62 208.5 0.0 1.9 2 0 0 2 2 2 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 XP_011275663.1 - 9.7e-55 184.0 1.8 2.8e-54 182.5 1.2 1.8 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 XP_011275663.1 - 2.7e-11 43.5 1.7 0.0042 17.3 0.0 4.2 3 1 1 4 4 4 3 HEAT repeats Cnd1 PF12717.2 XP_011275663.1 - 0.00071 19.4 11.2 0.49 10.2 0.0 4.6 2 1 2 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 XP_011275663.1 - 0.00071 19.9 0.6 5.3 7.6 0.0 5.3 5 2 1 6 6 6 1 HEAT-like repeat AP4E_app_platf PF14807.1 XP_011275663.1 - 0.0073 16.5 0.0 0.051 13.8 0.0 2.5 2 0 0 2 2 2 1 Adaptin AP4 complex epsilon appendage platform HEAT PF02985.17 XP_011275663.1 - 0.0089 16.0 0.0 2.2 8.5 0.0 4.0 4 0 0 4 4 4 1 HEAT repeat Ribosomal_L5_C PF00673.16 XP_011275664.1 - 9.2e-26 89.4 0.0 2.5e-25 88.0 0.0 1.8 2 0 0 2 2 2 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 XP_011275664.1 - 0.019 14.7 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L5 Ribosomal_L7Ae PF01248.21 XP_011275665.1 - 2.8e-27 94.0 0.1 1.1e-26 92.0 0.0 1.8 1 1 1 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ribosomal_L36e PF01158.13 XP_011275665.1 - 0.99 9.3 7.5 0.6 10.0 3.9 1.6 2 0 0 2 2 2 0 Ribosomal protein L36e Aconitase PF00330.15 XP_011275666.1 - 9e-77 258.5 0.0 1.2e-46 159.1 0.0 2.3 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 XP_011275666.1 - 3.8e-26 91.7 0.0 9.1e-26 90.5 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain Reticulon PF02453.12 XP_011275668.1 - 4.4e-33 114.2 1.6 7.3e-33 113.5 1.1 1.3 1 0 0 1 1 1 1 Reticulon Aminotran_1_2 PF00155.16 XP_011275669.1 - 5.5e-75 252.5 0.0 7e-75 252.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 XP_011275669.1 - 2.1e-07 30.0 0.0 4.2e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 XP_011275669.1 - 5.2e-06 24.9 0.0 8.5e-06 24.2 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 XP_011275669.1 - 0.016 14.2 0.1 0.3 10.0 0.0 2.2 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family MFS_1 PF07690.11 XP_011275670.1 - 5.1e-23 81.3 23.2 1e-21 77.0 15.5 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Caudo_TAP PF02413.12 XP_011275671.1 - 0.45 10.6 9.1 0.26 11.4 4.9 1.6 1 1 0 1 1 1 0 Caudovirales tail fibre assembly protein Iron_traffic PF04362.9 XP_011275671.1 - 2 7.8 12.0 1.3 8.4 0.4 3.0 1 1 2 3 3 3 0 Bacterial Fe(2+) trafficking CAF-1_p150 PF11600.3 XP_011275671.1 - 2.8 7.2 21.1 3.8 6.8 14.6 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DnaJ PF00226.26 XP_011275672.1 - 2e-23 81.8 1.1 4e-23 80.9 0.8 1.5 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 XP_011275672.1 - 4.7e-19 68.0 1.3 2.6e-15 56.0 0.1 3.1 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 XP_011275672.1 - 1.1e-10 41.3 12.6 1.1e-10 41.3 8.8 2.0 2 0 0 2 2 2 1 DnaJ central domain DZR PF12773.2 XP_011275672.1 - 8.4 6.2 9.3 6.5 6.6 1.6 2.3 1 1 1 2 2 2 0 Double zinc ribbon Peptidase_M1 PF01433.15 XP_011275673.1 - 1.3e-88 297.7 3.8 1.3e-88 297.6 1.7 1.6 2 0 0 2 2 2 1 Peptidase family M1 ERAP1_C PF11838.3 XP_011275673.1 - 9.8e-44 149.8 0.1 1.6e-43 149.2 0.1 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 XP_011275673.1 - 2.3e-13 50.2 0.0 5.8e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase MA superfamily DUF3633 PF12315.3 XP_011275673.1 - 0.041 13.1 0.1 0.21 10.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3633) Peptidase_M61 PF05299.7 XP_011275673.1 - 3.5 7.6 8.5 27 4.7 0.1 3.0 2 1 0 2 2 2 0 M61 glycyl aminopeptidase Mito_carr PF00153.22 XP_011275675.1 - 2.2e-10 40.0 0.1 4.1e-10 39.2 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial carrier protein DUF3525 PF12039.3 XP_011275675.1 - 0.053 12.0 0.2 0.15 10.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3525) DuffyBP_N PF12377.3 XP_011275675.1 - 0.13 12.5 1.0 1.3 9.2 0.1 2.6 2 0 0 2 2 2 0 Duffy binding protein N terminal MMS19_N PF14500.1 XP_011275676.1 - 2.4e-92 308.9 12.2 2.2e-91 305.7 1.3 4.0 4 0 0 4 4 4 2 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.3 XP_011275676.1 - 2.4e-73 247.2 20.3 2.4e-73 247.2 14.1 3.3 2 1 1 3 3 3 1 RNAPII transcription regulator C-terminal HEAT_2 PF13646.1 XP_011275676.1 - 2.3e-05 24.5 0.1 0.5 10.6 0.0 4.7 3 1 1 4 4 4 1 HEAT repeats HEAT_EZ PF13513.1 XP_011275676.1 - 0.0014 19.0 2.2 4.9 7.7 0.0 5.7 5 1 1 6 6 6 1 HEAT-like repeat UME PF08064.8 XP_011275676.1 - 0.0016 18.3 15.7 0.011 15.6 0.3 5.8 5 1 1 6 6 6 2 UME (NUC010) domain HEAT PF02985.17 XP_011275676.1 - 0.0025 17.7 0.1 82 3.6 0.0 5.2 5 1 0 5 5 5 0 HEAT repeat RIX1 PF08167.7 XP_011275676.1 - 0.37 10.4 14.6 0.012 15.2 2.0 4.1 4 0 0 4 4 4 0 rRNA processing/ribosome biogenesis 6PGD PF00393.14 XP_011275677.1 - 6e-134 445.7 0.0 8e-134 445.3 0.0 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 XP_011275677.1 - 3.4e-53 179.8 0.0 5.2e-53 179.2 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 XP_011275677.1 - 0.0015 18.8 0.2 0.0032 17.8 0.2 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 XP_011275677.1 - 0.028 13.5 0.1 0.064 12.4 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_11 PF14833.1 XP_011275677.1 - 0.099 12.7 0.0 0.29 11.1 0.0 1.8 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 3HCDH_N PF02737.13 XP_011275677.1 - 0.11 12.1 0.2 0.46 10.1 0.1 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sec23_trunk PF04811.10 XP_011275678.1 - 1.3e-61 208.0 0.0 1.9e-61 207.5 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.7 XP_011275678.1 - 6.6e-30 103.4 0.9 1.7e-29 102.1 0.2 2.1 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.10 XP_011275678.1 - 2.3e-28 97.6 0.1 4.8e-28 96.6 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 XP_011275678.1 - 1.4e-13 50.1 2.8 2.4e-13 49.3 1.9 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 XP_011275678.1 - 2e-09 36.9 0.0 4.3e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat zf-MIZ PF02891.15 XP_011275678.1 - 0.027 13.9 0.1 0.064 12.7 0.1 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger tRNA-synt_2 PF00152.15 XP_011275679.1 - 2.8e-76 256.4 0.4 4.1e-76 255.9 0.2 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 XP_011275679.1 - 2.1e-10 40.3 0.1 3.9e-10 39.4 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 XP_011275679.1 - 4.1e-06 26.1 0.3 0.0031 16.7 0.1 2.6 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 XP_011275679.1 - 0.00048 19.7 0.2 0.54 9.8 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) Acetyltransf_4 PF13420.1 XP_011275679.1 - 0.025 14.5 0.1 0.055 13.4 0.1 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3381 PF11861.3 XP_011275679.1 - 0.037 13.5 1.4 0.072 12.5 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) SEA PF01390.15 XP_011275679.1 - 0.044 13.4 0.3 0.14 11.8 0.2 1.8 1 0 0 1 1 1 0 SEA domain DUF4441 PF14536.1 XP_011275680.1 - 0.46 10.4 4.9 0.93 9.4 3.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4441) RNase_HII PF01351.13 XP_011275681.1 - 1e-55 188.5 0.0 1.2e-55 188.2 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII HD PF01966.17 XP_011275682.1 - 5.4e-10 39.3 0.0 1.3e-09 38.1 0.0 1.7 1 1 0 1 1 1 1 HD domain 2-oxoacid_dh PF00198.18 XP_011275683.1 - 8.3e-73 244.4 0.6 1.2e-72 243.9 0.1 1.4 2 0 0 2 2 2 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) E3_binding PF02817.12 XP_011275683.1 - 1.4e-16 59.8 3.6 1.4e-16 59.8 0.2 2.3 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl PF00364.17 XP_011275683.1 - 3.7e-14 52.0 0.0 7.8e-14 51.0 0.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme DUF3614 PF12267.3 XP_011275683.1 - 0.2 11.9 0.1 0.2 11.9 0.1 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF3614) Mito_carr PF00153.22 XP_011275684.1 - 8.2e-62 204.9 0.2 3.3e-21 74.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF89 PF01937.14 XP_011275684.1 - 0.094 11.4 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF89 Ribosomal_L13 PF00572.13 XP_011275685.1 - 3.6e-26 91.7 0.3 5.4e-26 91.1 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L13 ubiquitin PF00240.18 XP_011275687.1 - 4.6e-05 22.7 0.2 7.8e-05 21.9 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.1 XP_011275687.1 - 0.00012 21.8 2.4 0.00039 20.2 1.7 1.9 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD PF11976.3 XP_011275687.1 - 0.032 13.9 0.0 0.056 13.1 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF4363 PF14276.1 XP_011275687.1 - 0.93 9.2 5.6 0.12 12.0 0.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) Fork_head PF00250.13 XP_011275688.1 - 8.3e-38 128.3 1.3 1.9e-37 127.1 0.9 1.6 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 XP_011275688.1 - 2.1e-06 27.7 0.0 6.7e-06 26.1 0.0 2.0 1 0 0 1 1 1 1 FHA domain RNA_pol_I_TF PF04090.7 XP_011275689.1 - 3.3e-45 153.8 0.5 6.8e-45 152.7 0.4 1.5 1 0 0 1 1 1 1 RNA polymerase I specific initiation factor Prothymosin PF03247.9 XP_011275689.1 - 0.077 13.1 71.7 0.081 13.0 12.0 4.2 3 1 1 4 4 4 0 Prothymosin/parathymosin family zf-RING_2 PF13639.1 XP_011275690.1 - 2e-11 43.5 2.8 3.5e-11 42.7 1.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 XP_011275690.1 - 1.7e-10 40.8 0.6 3.2e-10 39.9 0.4 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 XP_011275690.1 - 1.2e-05 24.8 2.7 4.9e-05 22.9 2.1 1.8 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 XP_011275690.1 - 1.2e-05 24.8 1.8 2.1e-05 24.1 1.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 XP_011275690.1 - 5.4e-05 23.1 2.7 0.00014 21.8 1.8 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 XP_011275690.1 - 0.00013 21.6 1.3 0.00034 20.2 0.9 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.20 XP_011275690.1 - 0.00014 21.4 2.3 0.00025 20.6 1.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 XP_011275690.1 - 0.0066 15.9 1.5 0.014 14.9 1.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.1 XP_011275690.1 - 0.0092 15.8 1.1 0.025 14.4 0.8 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 XP_011275690.1 - 0.018 14.8 3.3 0.054 13.3 2.3 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 XP_011275690.1 - 0.35 10.9 3.9 0.75 9.8 2.7 1.6 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 XP_011275690.1 - 1 9.3 3.3 6.9 6.7 2.3 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain OPA3 PF07047.7 XP_011275691.1 - 4e-15 55.7 0.2 4e-15 55.7 0.1 2.3 2 1 0 2 2 2 1 Optic atrophy 3 protein (OPA3) HR1 PF02185.11 XP_011275691.1 - 0.0099 15.5 0.1 0.0099 15.5 0.1 3.1 3 0 0 3 3 3 1 Hr1 repeat RapA_C PF12137.3 XP_011275691.1 - 0.018 13.8 1.1 0.023 13.5 0.8 1.2 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal SlyX PF04102.7 XP_011275691.1 - 0.074 13.4 0.7 5.6 7.4 0.0 2.5 2 0 0 2 2 2 0 SlyX RNA_polI_A14 PF08203.6 XP_011275691.1 - 0.092 13.0 0.9 0.18 12.0 0.6 1.5 1 0 0 1 1 1 0 Yeast RNA polymerase I subunit RPA14 Med11 PF10280.4 XP_011275691.1 - 0.37 10.8 7.0 0.082 12.9 2.4 1.7 2 0 0 2 2 2 0 Mediator complex protein DUF2681 PF10883.3 XP_011275691.1 - 0.38 10.9 0.1 0.38 10.9 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2681) DUF3373 PF11853.3 XP_011275691.1 - 0.56 8.6 2.8 0.72 8.3 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) DUF972 PF06156.8 XP_011275691.1 - 1.2 9.4 5.9 7 7.0 1.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Syntaxin PF00804.20 XP_011275691.1 - 2.1 8.5 12.1 1.9 8.6 1.5 2.2 1 1 1 2 2 2 0 Syntaxin DUF904 PF06005.7 XP_011275691.1 - 4.4 7.6 11.9 2.8e+02 1.8 8.2 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF904) bZIP_Maf PF03131.12 XP_011275691.1 - 5.5 7.3 7.7 3.3 8.0 0.2 2.2 2 0 0 2 2 2 0 bZIP Maf transcription factor Ribosomal_L16 PF00252.13 XP_011275692.1 - 2.3e-33 114.7 0.1 3.8e-33 114.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e zf-C2H2_jaz PF12171.3 XP_011275693.1 - 5.8e-09 35.8 8.0 1.1e-08 34.9 5.6 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 XP_011275693.1 - 0.004 17.2 2.1 0.0042 17.1 0.2 1.8 1 1 1 2 2 2 1 C2H2 type zinc-finger (2 copies) AKAP95 PF04988.7 XP_011275693.1 - 0.0067 16.2 3.1 0.01 15.6 2.1 1.3 1 0 0 1 1 1 1 A-kinase anchoring protein 95 (AKAP95) zf-U1 PF06220.7 XP_011275693.1 - 0.039 13.5 4.2 0.078 12.5 2.9 1.5 1 0 0 1 1 1 0 U1 zinc finger MAS20 PF02064.10 XP_011275693.1 - 0.051 13.4 0.5 0.082 12.8 0.4 1.4 1 0 0 1 1 1 0 MAS20 protein import receptor zf-met PF12874.2 XP_011275693.1 - 0.12 12.6 2.5 0.23 11.7 1.7 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type OTU PF02338.14 XP_011275694.1 - 3.5e-10 40.5 0.0 6.5e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease Antitoxin-MazE PF04014.13 XP_011275694.1 - 0.13 12.0 0.1 0.34 10.6 0.1 1.6 1 0 0 1 1 1 0 Antidote-toxin recognition MazE JAB PF01398.16 XP_011275695.1 - 2.2e-16 59.6 0.0 3.6e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 XP_011275695.1 - 2.1e-06 27.2 0.0 3.8e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain eIF2A PF08662.6 XP_011275696.1 - 3.7e-80 268.2 0.0 3.5e-78 261.7 0.0 2.5 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 XP_011275696.1 - 0.0023 17.7 1.7 1.4 8.9 0.1 4.3 3 1 0 3 3 3 1 WD domain, G-beta repeat CGI-121 PF08617.5 XP_011275697.1 - 9.1e-23 80.7 1.0 1e-22 80.5 0.7 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Vps8 PF12816.2 XP_011275698.1 - 1.8e-54 183.9 1.6 1.8e-54 183.9 1.1 2.9 3 0 0 3 3 3 1 Golgi CORVET complex core vacuolar protein 8 zf-RING_5 PF14634.1 XP_011275698.1 - 0.0034 17.0 0.4 0.0034 17.0 0.3 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 XP_011275698.1 - 0.01 15.6 0.7 0.027 14.2 0.5 1.7 1 0 0 1 1 1 0 Ring finger domain zf-rbx1 PF12678.2 XP_011275698.1 - 0.013 15.5 2.4 0.03 14.4 1.7 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger WD40 PF00400.27 XP_011275698.1 - 0.031 14.1 1.8 0.2 11.6 0.1 3.1 3 0 0 3 3 3 0 WD domain, G-beta repeat zf-C3HC4_2 PF13923.1 XP_011275698.1 - 0.098 12.7 0.9 0.31 11.1 0.6 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 XP_011275698.1 - 0.13 11.9 4.2 0.037 13.6 0.5 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) 3Beta_HSD PF01073.14 XP_011275700.1 - 2e-84 282.6 0.0 2.5e-84 282.3 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 XP_011275700.1 - 8.1e-29 100.7 0.0 1e-28 100.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 XP_011275700.1 - 7.4e-14 51.2 0.0 5.2e-13 48.5 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 XP_011275700.1 - 1.3e-12 47.2 0.0 2e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 XP_011275700.1 - 1.2e-09 37.5 0.0 2.2e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 XP_011275700.1 - 4.6e-09 36.5 0.0 6.4e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 XP_011275700.1 - 5.7e-06 26.3 0.0 1.9e-05 24.6 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 XP_011275700.1 - 0.00052 19.7 0.0 0.003 17.2 0.0 2.0 1 1 0 1 1 1 1 KR domain NmrA PF05368.8 XP_011275700.1 - 0.001 18.3 0.0 0.0015 17.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family N6-adenineMlase PF10237.4 XP_011275702.1 - 2.1e-59 199.7 0.1 2.9e-59 199.3 0.1 1.2 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Cons_hypoth95 PF03602.10 XP_011275702.1 - 0.24 10.7 1.0 0.57 9.5 0.1 2.0 2 1 0 2 2 2 0 Conserved hypothetical protein 95 V-SNARE_C PF12352.3 XP_011275703.1 - 1.9e-08 34.2 0.4 4e-08 33.2 0.3 1.6 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 XP_011275703.1 - 9.8e-06 25.1 1.2 2.1e-05 24.1 0.0 2.2 2 0 0 2 2 2 1 Sec20 Pentapeptide_4 PF13599.1 XP_011275703.1 - 0.0062 16.3 0.2 0.091 12.5 0.0 2.9 3 0 0 3 3 3 1 Pentapeptide repeats (9 copies) Sigma70_r4 PF04545.11 XP_011275703.1 - 0.013 14.8 0.0 0.026 13.8 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 Snapin_Pallidin PF14712.1 XP_011275703.1 - 0.098 12.9 6.6 0.091 13.0 2.6 2.4 2 0 0 2 2 2 0 Snapin/Pallidin F-box PF00646.28 XP_011275703.1 - 0.13 11.9 1.4 0.33 10.6 1.0 1.7 1 0 0 1 1 1 0 F-box domain IncA PF04156.9 XP_011275703.1 - 6.7 6.2 12.2 4.6 6.8 2.4 2.5 2 0 0 2 2 2 0 IncA protein RCC1 PF00415.13 XP_011275704.1 - 6.7e-24 83.8 0.5 3.7e-07 30.2 0.0 5.7 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 XP_011275704.1 - 1.8e-16 59.2 10.6 1.2e-10 40.6 0.1 5.4 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat DUF1640 PF07798.6 XP_011275705.1 - 3.9e-66 222.4 6.0 4.4e-66 222.2 4.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) SF-assemblin PF06705.6 XP_011275705.1 - 0.0015 17.7 5.6 0.0022 17.1 3.9 1.3 1 0 0 1 1 1 1 SF-assemblin/beta giardin FlaC_arch PF05377.6 XP_011275705.1 - 0.0058 16.4 3.0 0.74 9.7 0.3 2.6 2 0 0 2 2 2 2 Flagella accessory protein C (FlaC) DUF3375 PF11855.3 XP_011275705.1 - 0.044 12.5 5.5 1.3 7.6 3.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3375) Syntaxin PF00804.20 XP_011275705.1 - 0.045 13.9 10.5 0.66 10.1 0.4 2.3 1 1 1 2 2 2 0 Syntaxin HALZ PF02183.13 XP_011275705.1 - 0.057 13.1 0.5 0.86 9.3 0.2 2.4 3 0 0 3 3 3 0 Homeobox associated leucine zipper Apolipoprotein PF01442.13 XP_011275705.1 - 0.084 12.3 2.6 0.16 11.4 1.8 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF2939 PF11159.3 XP_011275705.1 - 0.1 12.7 0.4 22 5.3 0.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2939) RICH PF05062.7 XP_011275705.1 - 0.12 12.4 1.8 0.44 10.7 0.5 2.1 2 0 0 2 2 2 0 RICH domain COG5 PF10392.4 XP_011275705.1 - 0.13 12.1 3.0 2.1 8.3 1.9 2.4 1 1 0 1 1 1 0 Golgi transport complex subunit 5 TBPIP PF07106.8 XP_011275705.1 - 0.17 11.4 7.0 0.36 10.3 4.8 1.5 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) WXG100 PF06013.7 XP_011275705.1 - 0.2 11.7 2.2 13 5.8 0.2 2.7 2 0 0 2 2 2 0 Proteins of 100 residues with WXG Phage_lysis PF03245.8 XP_011275705.1 - 0.4 10.6 4.7 5.1 7.1 0.2 2.3 1 1 1 2 2 2 0 Bacteriophage Rz lysis protein Baculo_PEP_C PF04513.7 XP_011275705.1 - 0.44 10.3 3.9 1.1 9.1 1.8 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF904 PF06005.7 XP_011275705.1 - 0.97 9.7 8.3 53 4.2 5.7 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF904) Tox-URI2 PF15653.1 XP_011275705.1 - 1.6 8.9 4.3 49 4.2 2.5 3.0 2 1 1 3 3 3 0 URI fold toxin 2 DUF972 PF06156.8 XP_011275705.1 - 5.3 7.4 6.4 51 4.2 4.4 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF972) PMM PF03332.8 XP_011275706.1 - 8e-112 372.1 1.1 9.1e-112 371.9 0.8 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 XP_011275706.1 - 2.7e-07 30.4 0.0 1.5e-06 27.9 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 XP_011275706.1 - 0.00098 18.4 0.0 0.37 10.0 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.21 XP_011275706.1 - 0.051 13.9 0.0 0.12 12.7 0.0 1.7 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase TMPIT PF07851.8 XP_011275706.1 - 0.053 12.5 0.0 0.072 12.1 0.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein HAD PF12710.2 XP_011275706.1 - 0.1 12.7 0.0 0.14 12.2 0.0 1.6 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase F420_oxidored PF03807.12 XP_011275707.1 - 5.5e-17 61.9 0.0 1.1e-16 61.0 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 XP_011275707.1 - 1.9e-09 37.6 0.0 4.8e-09 36.2 0.0 1.7 1 1 1 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 XP_011275707.1 - 1.7e-05 24.5 0.0 3.1e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TusA PF01206.12 XP_011275707.1 - 0.0056 16.2 0.0 0.025 14.1 0.0 2.1 2 0 0 2 2 2 1 Sulfurtransferase TusA 2-Hacid_dh_C PF02826.14 XP_011275707.1 - 0.018 14.2 0.0 0.028 13.5 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF3005 PF11448.3 XP_011275707.1 - 0.073 12.6 0.0 7.6 6.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3005) NAD_Gly3P_dh_N PF01210.18 XP_011275707.1 - 0.1 12.3 0.3 0.36 10.5 0.1 2.1 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 XP_011275708.1 - 5.9e-13 49.0 0.2 1.4e-12 47.9 0.0 1.7 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 XP_011275708.1 - 0.00016 21.5 0.0 0.00029 20.7 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Semialdhyde_dh PF01118.19 XP_011275708.1 - 0.0042 17.3 0.0 0.011 16.0 0.0 1.7 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 XP_011275708.1 - 0.0089 15.6 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 XP_011275708.1 - 0.017 14.2 0.0 0.027 13.6 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 XP_011275708.1 - 0.097 12.7 0.0 0.23 11.5 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 XP_011275708.1 - 0.15 12.0 0.1 0.21 11.5 0.1 1.5 1 1 0 1 1 1 0 NADH(P)-binding F420_oxidored PF03807.12 XP_011275709.1 - 8.3e-14 51.7 0.2 1.8e-13 50.7 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 XP_011275709.1 - 2.3e-05 24.3 0.0 5.4e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 XP_011275709.1 - 0.00068 18.8 0.1 0.0011 18.1 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 XP_011275709.1 - 0.0067 16.1 0.4 0.012 15.2 0.1 1.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sulfatase PF00884.18 XP_011275709.1 - 0.046 12.9 0.1 0.058 12.5 0.1 1.2 1 0 0 1 1 1 0 Sulfatase F420_oxidored PF03807.12 XP_011275710.1 - 2e-13 50.5 0.9 3.5e-13 49.7 0.2 1.7 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 XP_011275710.1 - 0.00017 21.4 0.0 0.00033 20.5 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 XP_011275710.1 - 0.00025 20.2 0.1 0.00037 19.6 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 XP_011275710.1 - 0.00055 19.6 0.1 0.0011 18.6 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 XP_011275710.1 - 0.1 12.9 0.2 0.34 11.2 0.1 1.9 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.12 XP_011275711.1 - 5.8e-14 52.2 0.6 1e-13 51.5 0.1 1.6 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 XP_011275711.1 - 4.6e-05 23.3 0.0 8.8e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 XP_011275711.1 - 0.00066 18.8 0.1 0.00095 18.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 XP_011275711.1 - 0.0021 17.7 0.1 0.0038 16.9 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Zn_clus PF00172.13 XP_011275712.1 - 6.2e-06 26.0 14.0 1.2e-05 25.0 9.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 XP_011275712.1 - 0.00013 20.8 6.0 0.00016 20.6 3.3 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Phage_integ_N PF09003.5 XP_011275712.1 - 0.027 14.1 0.3 7.3 6.3 0.3 2.5 2 0 0 2 2 2 0 Bacteriophage lambda integrase, N-terminal domain Fungal_trans PF04082.13 XP_011275714.1 - 9e-17 60.8 0.3 5e-16 58.3 0.2 2.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 XP_011275714.1 - 1.8e-07 30.9 7.8 4.1e-07 29.8 5.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pox_A_type_inc PF04508.7 XP_011275714.1 - 0.0044 16.6 0.9 0.019 14.7 0.6 2.2 1 0 0 1 1 1 1 Viral A-type inclusion protein repeat Fungal_trans PF04082.13 XP_011275715.1 - 8.9e-19 67.3 4.3 8.9e-19 67.3 3.0 2.5 2 1 0 2 2 2 1 Fungal specific transcription factor domain IncA PF04156.9 XP_011275715.1 - 2 7.9 7.5 7.4 6.1 5.2 1.9 1 0 0 1 1 1 0 IncA protein WAPL PF07814.8 XP_011275716.1 - 1.4e-07 30.6 0.4 1.4e-07 30.6 0.3 3.0 2 1 0 3 3 3 2 Wings apart-like protein regulation of heterochromatin DEAD PF00270.24 XP_011275717.1 - 2.7e-42 144.1 0.2 6.2e-42 142.9 0.1 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF4217 PF13959.1 XP_011275717.1 - 9.2e-22 76.3 0.0 2.1e-21 75.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 XP_011275717.1 - 8.4e-19 67.2 0.0 1.8e-18 66.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 XP_011275717.1 - 0.00019 21.3 0.0 0.00069 19.4 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 XP_011275717.1 - 0.0024 16.7 0.0 0.004 15.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Pheromone PF08015.6 XP_011275718.1 - 0.002 18.8 0.1 0.0025 18.5 0.1 1.2 1 0 0 1 1 1 1 Fungal mating-type pheromone Thioredoxin PF00085.15 XP_011275720.1 - 2.3e-24 85.0 0.0 2.5e-24 84.9 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 XP_011275720.1 - 7e-08 32.4 0.0 1.7e-07 31.2 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 XP_011275720.1 - 9.8e-07 28.3 0.0 1.1e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 XP_011275720.1 - 1.1e-06 28.8 0.1 7.8e-06 26.0 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 XP_011275720.1 - 5e-05 23.2 0.0 8.1e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 XP_011275720.1 - 9.4e-05 22.0 0.0 0.00012 21.7 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family HyaE PF07449.6 XP_011275720.1 - 0.012 15.5 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Glutaredoxin PF00462.19 XP_011275720.1 - 0.014 15.4 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin Phosducin PF02114.11 XP_011275720.1 - 0.034 12.8 0.0 0.041 12.6 0.0 1.0 1 0 0 1 1 1 0 Phosducin DUF713 PF05218.9 XP_011275720.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF713) Redoxin PF08534.5 XP_011275720.1 - 0.15 11.6 0.0 0.35 10.4 0.0 1.5 1 1 1 2 2 2 0 Redoxin Thioredoxin PF00085.15 XP_011275721.1 - 5.3e-29 99.9 0.0 6.6e-29 99.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 XP_011275721.1 - 1.7e-09 37.8 0.3 9.9e-09 35.3 0.2 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 XP_011275721.1 - 5.1e-08 32.9 0.1 2.1e-05 24.5 0.0 2.5 1 1 2 3 3 3 2 Thioredoxin-like Thioredoxin_9 PF14595.1 XP_011275721.1 - 1.5e-07 30.9 0.0 1.8e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.5 XP_011275721.1 - 3.4e-05 23.4 0.2 0.0029 17.1 0.1 2.1 1 1 1 2 2 2 1 Redoxin AhpC-TSA PF00578.16 XP_011275721.1 - 0.00011 21.8 0.2 0.001 18.7 0.1 2.0 1 1 1 2 2 2 1 AhpC/TSA family HyaE PF07449.6 XP_011275721.1 - 0.0012 18.7 0.0 0.0019 18.1 0.0 1.3 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE Glutaredoxin PF00462.19 XP_011275721.1 - 0.0012 18.7 0.0 0.0023 17.8 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.1 XP_011275721.1 - 0.0059 16.3 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin domain Phosducin PF02114.11 XP_011275721.1 - 0.0092 14.7 0.0 0.01 14.5 0.0 1.1 1 0 0 1 1 1 1 Phosducin Thioredoxin_5 PF13743.1 XP_011275721.1 - 0.016 14.8 0.1 0.051 13.1 0.0 1.9 1 1 1 2 2 2 0 Thioredoxin Thioredoxin_7 PF13899.1 XP_011275721.1 - 0.022 14.7 0.2 0.062 13.3 0.1 1.7 1 1 0 1 1 1 0 Thioredoxin-like DUF836 PF05768.9 XP_011275721.1 - 0.051 13.8 0.0 0.089 13.0 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) DSBA PF01323.15 XP_011275721.1 - 0.072 12.6 0.3 0.26 10.7 0.0 1.9 1 1 1 2 2 2 0 DSBA-like thioredoxin domain TraF PF13728.1 XP_011275721.1 - 0.12 11.8 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein DUF1064 PF06356.6 XP_011275722.1 - 0.027 14.4 0.3 0.058 13.3 0.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1064) HALZ PF02183.13 XP_011275722.1 - 0.36 10.5 2.4 0.99 9.1 0.2 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper AAA_23 PF13476.1 XP_011275722.1 - 0.36 11.1 7.4 0.52 10.6 5.1 1.2 1 0 0 1 1 1 0 AAA domain CAP PF00188.21 XP_011275724.1 - 1.9e-20 73.5 3.5 1.9e-20 73.5 2.4 2.8 2 1 0 2 2 2 1 Cysteine-rich secretory protein family Flocculin_t3 PF13928.1 XP_011275725.1 - 2.4e-09 37.1 17.5 1.1e-06 28.6 3.6 4.2 4 0 0 4 4 4 2 Flocculin type 3 repeat Cofilin_ADF PF00241.15 XP_011275726.1 - 6.9e-20 71.2 0.0 1.7e-19 69.9 0.0 1.7 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_1 PF00018.23 XP_011275726.1 - 8e-13 47.5 0.7 1.9e-12 46.3 0.5 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 XP_011275726.1 - 2.2e-12 46.3 0.2 4.7e-12 45.2 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 XP_011275726.1 - 1.5e-05 24.3 0.0 3e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain CRA PF06589.6 XP_011275726.1 - 0.0053 16.0 4.0 0.0053 16.0 2.8 2.8 4 1 1 5 5 5 1 Circumsporozoite-related antigen (CRA) Csm1 PF12539.3 XP_011275727.1 - 1.3e-24 86.4 1.0 2.4e-24 85.6 0.2 1.8 2 0 0 2 2 2 1 Chromosome segregation protein Csm1/Pcs1 Trypan_PARP PF05887.6 XP_011275727.1 - 0.11 12.2 21.5 0.21 11.4 14.9 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) WD40 PF00400.27 XP_011275728.1 - 1.5e-66 218.0 18.7 2.4e-11 43.0 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 XP_011275728.1 - 7.5e-27 93.3 9.9 1.5e-26 92.3 6.9 1.5 1 0 0 1 1 1 1 Tup N-terminal Nup160 PF11715.3 XP_011275728.1 - 0.00012 20.3 6.3 0.2 9.7 0.0 4.2 1 1 3 4 4 4 2 Nucleoporin Nup120/160 IKI3 PF04762.7 XP_011275728.1 - 0.00099 17.0 0.0 0.0031 15.4 0.0 1.9 1 1 0 1 1 1 1 IKI3 family PD40 PF07676.7 XP_011275728.1 - 0.013 15.2 0.1 22 4.8 0.0 4.8 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 XP_011275728.1 - 0.013 13.7 0.2 0.64 8.2 0.1 2.4 1 1 1 2 2 2 0 Cytochrome D1 heme domain Filament PF00038.16 XP_011275728.1 - 0.097 12.1 9.4 0.16 11.4 6.5 1.2 1 0 0 1 1 1 0 Intermediate filament protein Spc7 PF08317.6 XP_011275728.1 - 0.17 10.5 8.8 0.26 9.9 6.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein PAT1 PF09770.4 XP_011275728.1 - 0.78 7.9 68.2 1.1 7.4 47.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ERM PF00769.14 XP_011275728.1 - 3.8 6.9 15.6 0.11 11.9 6.3 1.7 2 0 0 2 2 2 0 Ezrin/radixin/moesin family GHMP_kinases_N PF00288.21 XP_011275729.1 - 2.2e-10 40.4 0.4 7e-10 38.8 0.3 1.9 1 0 0 1 1 1 1 GHMP kinases N terminal domain UbiA PF01040.13 XP_011275730.1 - 2.1e-29 102.5 13.9 2.6e-29 102.2 9.7 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family RRM_1 PF00076.17 XP_011275731.1 - 2.9e-15 55.6 0.0 4.6e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 XP_011275731.1 - 5.4e-09 35.9 0.0 9.4e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 XP_011275731.1 - 0.0022 17.8 0.0 0.0035 17.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OST3_OST6 PF04756.8 XP_011275732.1 - 0.031 13.8 0.0 0.058 12.9 0.0 1.4 1 0 0 1 1 1 0 OST3 / OST6 family UQ_con PF00179.21 XP_011275733.1 - 1.5e-27 95.7 0.1 2.6e-27 94.9 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 XP_011275733.1 - 0.01 15.7 0.3 0.023 14.5 0.0 1.8 2 0 0 2 2 2 1 RWD domain FliP PF00813.15 XP_011275733.1 - 0.19 11.4 0.1 0.32 10.6 0.0 1.3 1 1 0 1 1 1 0 FliP family Glyco_hydro_81 PF03639.8 XP_011275734.1 - 2.9e-248 825.4 21.8 2.9e-248 825.4 15.1 2.6 3 0 0 3 3 3 1 Glycosyl hydrolase family 81 Glyco_hydro_81 PF03639.8 XP_011275735.1 - 2.7e-241 802.4 11.9 3.4e-241 802.1 8.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 LicD PF04991.8 XP_011275736.1 - 4.2e-28 98.8 6.2 4.2e-28 98.8 4.3 2.9 3 0 0 3 3 3 1 LicD family Gly_transf_sug PF04488.10 XP_011275737.1 - 4.2e-12 46.3 0.9 1.9e-11 44.2 0.6 2.1 1 1 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif LicD PF04991.8 XP_011275738.1 - 7.5e-27 94.7 5.1 7.5e-27 94.7 3.6 3.3 2 1 1 3 3 3 1 LicD family LicD PF04991.8 XP_011275739.1 - 1.6e-27 96.9 4.9 1.6e-27 96.9 3.4 3.2 2 1 0 2 2 2 1 LicD family Prim-Pol PF09250.6 XP_011275739.1 - 0.05 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Bifunctional DNA primase/polymerase, N-terminal Trehalase_Ca-bi PF07492.6 XP_011275739.1 - 1.1 8.6 3.8 2.9 7.2 2.6 1.6 1 0 0 1 1 1 0 Neutral trehalase Ca2+ binding domain LicD PF04991.8 XP_011275740.1 - 1.4e-27 97.1 5.5 1.4e-27 97.1 3.8 2.8 3 0 0 3 3 3 1 LicD family Gly_transf_sug PF04488.10 XP_011275741.1 - 4.2e-10 39.9 0.5 1.2e-09 38.4 0.3 1.8 1 1 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif DUF2921 PF11145.3 XP_011275741.1 - 0.18 9.5 0.2 0.24 9.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2921) Gly_transf_sug PF04488.10 XP_011275742.1 - 9.1e-09 35.6 0.3 1.9e-08 34.6 0.2 1.7 1 1 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Gly_transf_sug PF04488.10 XP_011275743.1 - 1.2e-08 35.2 0.8 2.3e-08 34.3 0.1 1.8 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Pacs-1 PF10254.4 XP_011275744.1 - 0.071 11.7 0.1 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein Mannosyl_trans3 PF11051.3 XP_011275745.1 - 4e-40 137.8 0.3 6.7e-40 137.1 0.2 1.4 1 0 0 1 1 1 1 Mannosyltransferase putative Gly_transf_sug PF04488.10 XP_011275746.1 - 3.7e-09 36.8 0.0 1e-08 35.4 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 XP_011275746.1 - 0.0012 18.0 1.4 0.0024 17.0 0.9 1.5 1 1 0 1 1 1 1 Capsular polysaccharide synthesis protein Flocculin_t3 PF13928.1 XP_011275747.1 - 4.5e-39 132.3 87.6 2.5e-13 49.9 17.3 4.2 3 0 0 3 3 3 3 Flocculin type 3 repeat DUF3179 PF11376.3 XP_011275747.1 - 0.57 9.2 10.6 7.1 5.7 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3179) MFS_1 PF07690.11 XP_011275748.1 - 4.9e-38 130.7 20.1 4e-37 127.7 15.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily ESSS PF10183.4 XP_011275748.1 - 0.017 15.5 0.1 0.048 14.0 0.0 1.8 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF3357 PF11837.3 XP_011275748.1 - 0.17 11.7 0.0 1.3 8.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) Candida_ALS_N PF11766.3 XP_011275749.1 - 7.3e-30 103.6 7.7 7.3e-30 103.6 5.3 3.1 3 1 1 4 4 4 1 Cell-wall agglutinin N-terminal ligand-sugar binding Collagen PF01391.13 XP_011275750.1 - 0.66 9.5 6.7 1.5 8.4 4.6 1.6 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Candida_ALS_N PF11766.3 XP_011275752.1 - 8.3e-37 126.4 0.9 1.1e-36 125.9 0.7 1.2 1 0 0 1 1 1 1 Cell-wall agglutinin N-terminal ligand-sugar binding CwfJ_C_1 PF04677.10 XP_011275753.1 - 1.5e-28 98.8 0.8 4e-28 97.5 0.2 1.9 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 XP_011275753.1 - 2.7e-19 69.4 3.8 6e-19 68.3 2.6 1.6 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 Pkinase PF00069.20 XP_011275754.1 - 2.4e-52 177.6 0.0 2.1e-51 174.5 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011275754.1 - 1.6e-25 89.6 0.1 3.3e-19 68.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 XP_011275754.1 - 1.1e-05 24.5 0.2 0.00033 19.7 0.0 2.3 1 1 1 2 2 2 1 Kinase-like Pkinase_C PF00433.19 XP_011275754.1 - 0.00034 21.0 0.6 0.0014 19.0 0.4 2.1 1 0 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.18 XP_011275754.1 - 0.0009 19.0 0.0 0.0039 16.9 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 XP_011275754.1 - 0.0046 15.8 0.0 0.0081 15.0 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Pox_ser-thr_kin PF05445.6 XP_011275754.1 - 0.034 12.9 2.8 0.77 8.4 0.0 2.5 3 0 0 3 3 3 0 Poxvirus serine/threonine protein kinase Nop PF01798.13 XP_011275755.1 - 7.5e-34 116.1 0.0 1.7e-33 115.0 0.0 1.6 1 0 0 1 1 1 1 Putative snoRNA binding domain Prp31_C PF09785.4 XP_011275755.1 - 1.1e-30 106.5 4.3 2.9e-30 105.2 3.0 1.7 1 0 0 1 1 1 1 Prp31 C terminal domain NOSIC PF08060.8 XP_011275755.1 - 7.5e-16 57.6 0.7 2.7e-15 55.9 0.1 2.4 3 0 0 3 3 3 1 NOSIC (NUC001) domain tRNA-synt_1 PF00133.17 XP_011275756.1 - 2.3e-225 749.2 0.0 1.5e-224 746.4 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 XP_011275756.1 - 4.3e-34 117.4 0.8 1.6e-33 115.6 0.5 2.1 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 XP_011275756.1 - 2.3e-19 69.3 0.2 3.8e-11 42.2 0.0 4.5 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 XP_011275756.1 - 8.3e-11 41.5 16.3 3e-08 33.1 0.0 4.3 3 1 1 4 4 4 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.4 XP_011275756.1 - 0.0003 20.8 7.7 0.0003 20.8 5.3 3.1 2 0 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1e PF01406.14 XP_011275756.1 - 0.52 9.3 0.0 0.52 9.3 0.0 3.7 4 1 0 4 4 4 0 tRNA synthetases class I (C) catalytic domain Adaptin_binding PF10199.4 XP_011275756.1 - 5.1 7.3 16.3 0.12 12.6 1.4 2.6 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 RNase_PH PF01138.16 XP_011275757.1 - 4.5e-18 65.8 0.5 7.5e-18 65.1 0.3 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 XP_011275757.1 - 0.0034 17.2 0.0 0.0075 16.1 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Mito_carr PF00153.22 XP_011275758.1 - 1.2e-61 204.3 2.2 2.5e-21 75.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein CRF PF00473.12 XP_011275758.1 - 0.00094 19.2 0.1 0.77 9.8 0.0 2.6 3 0 0 3 3 3 2 Corticotropin-releasing factor family Peptidase_M20 PF01546.23 XP_011275759.1 - 1e-27 96.8 0.0 1.4e-27 96.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 XP_011275759.1 - 1e-10 41.3 0.0 1.7e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 XP_011275759.1 - 0.037 13.7 0.0 0.072 12.8 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M28 CDP-OH_P_transf PF01066.16 XP_011275760.1 - 1.1e-19 70.5 3.7 1.1e-19 70.5 2.5 2.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase RIX1 PF08167.7 XP_011275761.1 - 4.4e-35 120.8 1.7 4.4e-35 120.8 1.2 2.4 3 0 0 3 3 3 1 rRNA processing/ribosome biogenesis DUF676 PF05057.9 XP_011275762.1 - 1.6e-36 125.6 0.1 3.4e-36 124.5 0.1 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.20 XP_011275762.1 - 0.0043 16.6 0.0 0.015 14.9 0.0 1.9 1 0 0 1 1 1 1 Lipase (class 3) LRR_4 PF12799.2 XP_011275762.1 - 0.006 16.1 2.4 0.006 16.1 1.6 5.3 2 1 3 5 5 5 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 XP_011275762.1 - 0.0098 15.6 1.0 0.0098 15.6 0.7 4.3 4 1 0 4 4 4 2 Leucine rich repeat SNARE_assoc PF09335.6 XP_011275762.1 - 0.011 15.8 0.1 0.14 12.3 0.0 2.4 2 0 0 2 2 2 0 SNARE associated Golgi protein LRR_1 PF00560.28 XP_011275762.1 - 0.15 12.1 7.6 9.2 6.7 0.1 4.7 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_7 PF13504.1 XP_011275762.1 - 0.16 12.2 6.0 29 5.4 0.0 5.5 5 0 0 5 5 5 0 Leucine rich repeat LRR_6 PF13516.1 XP_011275762.1 - 1.7 8.9 12.4 4.4 7.6 0.0 4.7 5 0 0 5 5 5 0 Leucine Rich repeat F420_oxidored PF03807.12 XP_011275763.1 - 5.6e-14 52.3 0.2 1.3e-13 51.1 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 XP_011275763.1 - 7.3e-05 22.6 0.0 0.00016 21.5 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 XP_011275763.1 - 0.0064 15.6 0.1 0.01 15.0 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 XP_011275763.1 - 0.033 13.8 0.2 0.062 12.9 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain EamA PF00892.15 XP_011275764.1 - 5.4e-31 107.2 29.3 7.2e-18 64.8 5.8 2.4 2 1 0 2 2 2 2 EamA-like transporter family DUF914 PF06027.7 XP_011275764.1 - 2.7e-06 26.4 11.2 3.5e-06 26.1 7.7 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EmrE PF13536.1 XP_011275764.1 - 0.00023 21.3 9.4 0.00023 21.3 6.5 3.1 2 1 0 3 3 3 1 Multidrug resistance efflux transporter TPT PF03151.11 XP_011275764.1 - 0.14 11.8 21.0 0.11 12.1 4.8 2.7 2 1 0 2 2 2 0 Triose-phosphate Transporter family UAA PF08449.6 XP_011275764.1 - 0.14 11.0 12.4 0.94 8.3 1.4 3.2 1 1 2 3 3 3 0 UAA transporter family FA_desaturase PF00487.19 XP_011275764.1 - 0.32 10.3 7.6 0.11 11.9 0.1 2.4 2 0 0 2 2 2 0 Fatty acid desaturase TP_methylase PF00590.15 XP_011275765.1 - 1.7e-22 80.1 0.0 2.5e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases zf-DHHC PF01529.15 XP_011275766.1 - 2e-25 89.1 10.8 2e-25 89.1 7.5 2.0 1 1 1 2 2 2 1 DHHC palmitoyltransferase DUF4131 PF13567.1 XP_011275766.1 - 0.00056 19.3 0.9 0.015 14.7 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4131) CD20 PF04103.10 XP_011275766.1 - 0.012 15.5 0.4 0.012 15.5 0.3 2.2 3 0 0 3 3 3 0 CD20-like family DUF3611 PF12263.3 XP_011275766.1 - 0.037 13.4 2.7 3.1 7.1 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3611) DUF4117 PF13491.1 XP_011275766.1 - 0.18 11.2 4.2 0.27 10.6 0.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4117) YwiC PF14256.1 XP_011275766.1 - 0.24 11.5 7.0 0.068 13.2 1.5 2.2 2 1 0 2 2 2 0 YwiC-like protein Bax1-I PF01027.15 XP_011275766.1 - 0.4 10.2 10.5 0.076 12.6 2.6 2.1 2 0 0 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 DUF975 PF06161.6 XP_011275766.1 - 0.48 10.1 10.3 0.028 14.1 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF975) GFO_IDH_MocA PF01408.17 XP_011275767.1 - 5.5e-20 72.0 0.1 1.1e-19 71.1 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 XP_011275767.1 - 8.1e-10 38.5 0.0 1.4e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain DUF1048 PF06304.6 XP_011275767.1 - 0.0022 18.2 0.0 2.9 8.2 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF1048) RPW8 PF05659.6 XP_011275767.1 - 0.005 16.3 0.2 0.0084 15.6 0.1 1.3 1 0 0 1 1 1 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 TrmB PF01978.14 XP_011275767.1 - 0.02 14.5 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB F420_oxidored PF03807.12 XP_011275767.1 - 0.026 14.9 0.0 0.074 13.4 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF3712 PF12505.3 XP_011275768.1 - 0.025 14.6 0.4 0.33 10.9 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3712) DUF3244 PF11589.3 XP_011275768.1 - 0.036 13.7 2.7 0.36 10.5 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3244) Spc7 PF08317.6 XP_011275769.1 - 0.0034 16.1 0.1 0.0034 16.1 0.1 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein BLOC1_2 PF10046.4 XP_011275769.1 - 0.011 15.8 0.2 0.017 15.2 0.1 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Laminin_II PF06009.7 XP_011275769.1 - 0.069 12.9 0.1 0.071 12.8 0.1 1.1 1 0 0 1 1 1 0 Laminin Domain II UPF0118 PF01594.11 XP_011275769.1 - 0.17 10.8 0.1 0.18 10.7 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function DUF20 CRCB PF02537.10 XP_011275771.1 - 2e-30 105.0 16.3 3.6e-18 65.5 2.3 2.2 2 0 0 2 2 2 2 CrcB-like protein Iso_dh PF00180.15 XP_011275773.1 - 9.6e-70 235.2 0.0 1.1e-69 234.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Amidase PF01425.16 XP_011275774.1 - 6.3e-69 232.9 0.0 8e-69 232.5 0.0 1.1 1 0 0 1 1 1 1 Amidase A_deaminase PF00962.17 XP_011275775.1 - 3.3e-112 374.6 0.1 4.8e-112 374.1 0.1 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase MAT1 PF06391.8 XP_011275776.1 - 6.6e-48 162.9 28.4 9.6e-48 162.4 19.7 1.2 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4 PF00097.20 XP_011275776.1 - 0.001 18.6 4.8 0.0069 16.0 3.6 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 XP_011275776.1 - 0.0024 17.5 4.5 0.0041 16.7 3.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) tRNA-synt_1d PF00750.14 XP_011275776.1 - 0.022 13.6 8.1 0.034 12.9 5.5 1.4 1 1 0 1 1 1 0 tRNA synthetases class I (R) zf-RING_2 PF13639.1 XP_011275776.1 - 0.055 13.3 5.6 0.13 12.1 3.8 1.7 1 1 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.1 XP_011275776.1 - 0.1 12.6 6.6 0.35 10.9 4.7 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 XP_011275776.1 - 0.55 10.0 9.1 5.8 6.7 6.2 2.3 1 1 1 2 2 2 0 zinc-RING finger domain Vir_act_alpha_C PF10400.4 XP_011275776.1 - 1.1 9.6 5.9 1.2 9.5 2.2 2.2 1 1 0 2 2 2 0 Virulence activator alpha C-term F420_oxidored PF03807.12 XP_011275777.1 - 3.1e-16 59.5 0.0 1.2e-15 57.6 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 XP_011275777.1 - 1e-05 25.4 0.0 2.1e-05 24.4 0.0 1.5 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 XP_011275777.1 - 0.00016 20.8 0.0 0.00034 19.8 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 XP_011275777.1 - 0.00076 19.1 0.0 0.0021 17.7 0.0 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 XP_011275777.1 - 0.034 14.6 0.0 0.067 13.7 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.12 XP_011275778.1 - 5.5e-13 49.1 0.0 9.9e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 XP_011275778.1 - 7e-06 25.9 0.0 1.8e-05 24.6 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 XP_011275778.1 - 0.00013 21.7 0.0 0.00021 20.9 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 XP_011275778.1 - 0.0059 15.7 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 XP_011275778.1 - 0.038 14.0 0.0 0.066 13.3 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Retrotrans_gag PF03732.12 XP_011275779.1 - 0.004 17.1 0.3 0.011 15.7 0.2 1.8 1 1 0 1 1 1 1 Retrotransposon gag protein DUF3867 PF12983.2 XP_011275779.1 - 0.016 15.2 1.8 0.06 13.3 1.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3867) TPR_11 PF13414.1 XP_011275780.1 - 1.5e-19 69.4 10.4 8.5e-05 22.1 0.0 5.8 4 1 1 5 5 5 5 TPR repeat TPR_1 PF00515.23 XP_011275780.1 - 2.7e-10 39.4 3.8 0.012 15.1 0.0 6.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.12 XP_011275780.1 - 2.2e-07 30.2 22.7 0.02 14.7 0.0 8.0 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_12 PF13424.1 XP_011275780.1 - 2.6e-06 27.2 27.2 0.0016 18.3 0.2 6.3 6 1 1 7 7 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 XP_011275780.1 - 2.8e-05 24.3 17.8 0.87 10.4 0.4 8.0 7 1 1 8 8 7 1 Tetratricopeptide repeat TPR_8 PF13181.1 XP_011275780.1 - 6.5e-05 22.4 3.6 1.7 8.6 0.0 6.4 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.1 XP_011275780.1 - 0.012 16.2 0.4 0.023 15.3 0.3 6.5 5 1 2 7 7 6 0 Tetratricopeptide repeat tRNA-synt_2c PF01411.14 XP_011275780.1 - 0.065 11.5 7.8 4.6 5.4 5.9 2.1 2 0 0 2 2 2 0 tRNA synthetases class II (A) Ycf1 PF05758.7 XP_011275780.1 - 0.57 7.8 12.1 0.83 7.2 8.4 1.1 1 0 0 1 1 1 0 Ycf1 Borrelia_P83 PF05262.6 XP_011275780.1 - 5.8 5.0 20.0 9.4 4.3 13.9 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein Hid1 PF12722.2 XP_011275780.1 - 7.3 4.1 17.2 10 3.6 11.9 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein AUX_IAA PF02309.11 XP_011275780.1 - 8.7 6.0 15.6 19 4.9 10.8 1.6 1 0 0 1 1 1 0 AUX/IAA family HSP20 PF00011.16 XP_011275782.1 - 1.6e-19 69.6 1.1 5e-19 68.0 0.2 1.9 2 0 0 2 2 2 1 Hsp20/alpha crystallin family SNF2_N PF00176.18 XP_011275783.1 - 3e-60 203.5 0.1 4.4e-60 202.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 XP_011275783.1 - 4.6e-12 45.6 0.1 1.7e-11 43.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 XP_011275783.1 - 9.1e-10 38.2 0.6 2.1e-09 37.0 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 XP_011275783.1 - 1.6e-09 37.8 0.9 9.1e-09 35.4 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 XP_011275783.1 - 0.0015 17.5 0.4 0.011 14.7 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) DUF2439 PF10382.4 XP_011275783.1 - 0.0035 17.5 1.8 0.3 11.3 0.0 3.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2439) DEAD_2 PF06733.10 XP_011275783.1 - 0.0051 16.2 0.4 1.3 8.4 0.0 2.6 2 0 0 2 2 2 2 DEAD_2 Ank_5 PF13857.1 XP_011275784.1 - 0.0012 18.9 0.0 0.0025 17.9 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 XP_011275784.1 - 0.03 14.6 0.0 0.061 13.6 0.0 1.4 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank PF00023.25 XP_011275784.1 - 0.15 11.9 0.0 0.34 10.7 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeat URO-D PF01208.12 XP_011275785.1 - 2.7e-106 355.3 0.0 3.1e-106 355.1 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) PP1 PF07430.6 XP_011275785.1 - 0.0078 15.8 0.1 2.6 7.5 0.0 2.3 2 0 0 2 2 2 2 Phloem filament protein PP1 Sugar_tr PF00083.19 XP_011275786.1 - 2.8e-81 273.4 27.8 3.2e-81 273.1 19.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 XP_011275786.1 - 2.3e-14 52.8 36.5 2.3e-14 52.8 25.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily GATA PF00320.22 XP_011275787.1 - 6.5e-15 54.1 3.8 1.8e-14 52.7 2.6 1.8 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.7 XP_011275787.1 - 0.0018 17.5 0.4 0.0032 16.7 0.3 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding eIF-5_eIF-2B PF01873.12 XP_011275787.1 - 0.071 12.7 0.9 0.26 10.9 0.6 2.1 1 0 0 1 1 1 0 Domain found in IF2B/IF5 DOPA_dioxygen PF08883.6 XP_011275788.1 - 1.5e-26 92.4 0.1 1.7e-26 92.2 0.1 1.0 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family BTB_2 PF02214.17 XP_011275788.1 - 0.03 14.5 0.0 0.059 13.5 0.0 1.5 1 1 0 1 1 1 0 BTB/POZ domain Topo-VIb_trans PF09239.6 XP_011275789.1 - 0.054 13.0 0.0 0.08 12.4 0.0 1.2 1 0 0 1 1 1 0 Topoisomerase VI B subunit, transducer Med10 PF09748.4 XP_011275790.1 - 5.5e-39 132.9 0.0 6.5e-39 132.6 0.0 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex WD40 PF00400.27 XP_011275791.1 - 6.5e-08 32.1 0.0 0.014 15.2 0.0 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat DUF778 PF05608.7 XP_011275791.1 - 0.054 13.4 0.1 0.35 10.8 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF778) CDC45 PF02724.9 XP_011275791.1 - 0.18 9.7 25.6 2.2 6.2 0.1 2.3 2 0 0 2 2 2 0 CDC45-like protein Nop14 PF04147.7 XP_011275791.1 - 6.1 4.6 42.8 0.84 7.4 23.4 2.1 2 0 0 2 2 2 0 Nop14-like family IL28A PF15177.1 XP_011275792.1 - 0.036 13.5 0.3 0.073 12.5 0.2 1.5 1 0 0 1 1 1 0 Interleukin-28A AFG1_ATPase PF03969.11 XP_011275793.1 - 1.3e-57 195.3 0.0 2.4e-55 187.8 0.0 2.2 2 0 0 2 2 2 2 AFG1-like ATPase AAA_22 PF13401.1 XP_011275793.1 - 0.004 17.3 0.0 0.025 14.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 XP_011275793.1 - 0.01 16.0 0.3 2.7 8.2 0.0 3.3 3 0 0 3 3 3 0 ABC transporter RNA_helicase PF00910.17 XP_011275793.1 - 0.04 14.0 0.5 1.3 9.2 0.0 3.1 4 0 0 4 4 4 0 RNA helicase NACHT PF05729.7 XP_011275793.1 - 0.062 12.9 0.0 0.17 11.4 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.1 XP_011275793.1 - 0.19 11.7 0.0 0.57 10.1 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain DUF4574 PF15141.1 XP_011275794.1 - 0.1 12.3 0.1 0.27 10.9 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4574) Packaging_FI PF14000.1 XP_011275794.1 - 0.82 9.8 0.0 0.82 9.8 0.0 3.1 3 0 0 3 3 3 0 DNA packaging protein FI CMD PF02627.15 XP_011275795.1 - 6.8e-07 29.0 0.0 1.1e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family Myotub-related PF06602.9 XP_011275796.1 - 3.2e-129 430.7 3.7 4.2e-129 430.3 2.6 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Takusan PF04822.8 XP_011275796.1 - 0.0084 15.8 0.2 0.034 13.9 0.1 2.1 1 0 0 1 1 1 1 Takusan Y_phosphatase3 PF13350.1 XP_011275796.1 - 0.013 15.7 0.0 0.033 14.4 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family Yippee-Mis18 PF03226.9 XP_011275797.1 - 4.6e-19 68.2 1.0 5.6e-19 67.9 0.7 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly ZZ PF00569.12 XP_011275797.1 - 3.3 7.3 5.9 0.62 9.6 0.3 2.5 4 0 0 4 4 4 0 Zinc finger, ZZ type zf-LSD1 PF06943.7 XP_011275797.1 - 8 6.1 7.6 4.1 7.1 1.2 2.6 2 0 0 2 2 2 0 LSD1 zinc finger SET PF00856.23 XP_011275799.1 - 1.3e-23 84.1 0.1 1.3e-23 84.1 0.1 4.5 2 2 0 2 2 2 1 SET domain Ribosomal_S14 PF00253.16 XP_011275800.1 - 1.2e-08 34.1 0.1 2.3e-08 33.2 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e QLQ PF08880.6 XP_011275800.1 - 0.17 11.3 0.8 0.45 9.9 0.5 1.7 1 1 0 1 1 1 0 QLQ Cauli_VI PF01693.11 XP_011275801.1 - 1.7e-37 127.2 11.8 8.6e-18 64.0 0.8 3.5 3 0 0 3 3 3 3 Caulimovirus viroplasmin RNase_H PF00075.19 XP_011275801.1 - 3e-17 63.2 0.0 1e-16 61.4 0.0 1.9 2 0 0 2 2 2 1 RNase H CybS PF05328.7 XP_011275802.1 - 4.5e-55 184.8 0.6 5.2e-55 184.6 0.4 1.0 1 0 0 1 1 1 1 CybS Peptidase_M16 PF00675.15 XP_011275803.1 - 2.9e-26 92.0 0.2 5.8e-26 91.0 0.1 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 XP_011275803.1 - 1.4e-23 83.5 0.1 2.7e-23 82.5 0.0 1.5 2 0 0 2 2 2 1 Peptidase M16 inactive domain PPP4R2 PF09184.6 XP_011275804.1 - 2.5e-14 53.5 12.5 2.5e-14 53.5 8.7 2.3 1 1 1 2 2 2 1 PPP4R2 Death_2 PF14786.1 XP_011275804.1 - 0.07 12.8 0.4 0.19 11.4 0.0 1.9 2 0 0 2 2 2 0 Tube Death domain Ribosomal_S7 PF00177.16 XP_011275805.1 - 1.1e-31 109.4 0.9 1.1e-31 109.4 0.6 1.6 2 0 0 2 2 2 1 Ribosomal protein S7p/S5e PH_3 PF14593.1 XP_011275805.1 - 0.0083 15.9 0.1 0.017 14.9 0.1 1.5 1 0 0 1 1 1 1 PH domain Aldo_ket_red PF00248.16 XP_011275806.1 - 8.4e-47 159.3 0.0 1.1e-46 158.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family VanZ PF04892.7 XP_011275807.1 - 8.7e-15 54.8 2.2 1.2e-14 54.3 1.6 1.3 1 0 0 1 1 1 1 VanZ like family DUF4401 PF14351.1 XP_011275807.1 - 0.0053 15.7 1.0 0.0071 15.3 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4401) FUSC PF04632.7 XP_011275807.1 - 0.12 10.7 0.1 0.15 10.4 0.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family EF-hand_4 PF12763.2 XP_011275808.1 - 3e-38 129.7 0.0 5.7e-13 48.5 0.0 4.4 4 0 0 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 XP_011275808.1 - 9.2e-08 30.8 0.1 0.006 15.8 0.0 4.6 4 0 0 4 4 4 1 EF hand EF-hand_7 PF13499.1 XP_011275808.1 - 4.5e-07 29.9 0.0 0.074 13.1 0.0 3.8 3 0 0 3 3 3 2 EF-hand domain pair UBA PF00627.26 XP_011275808.1 - 5.5e-07 29.2 0.1 1.2e-06 28.1 0.1 1.5 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_6 PF13405.1 XP_011275808.1 - 6.6e-05 22.4 0.3 0.56 10.2 0.0 3.7 4 0 0 4 4 4 2 EF-hand domain EzrA PF06160.7 XP_011275808.1 - 0.00021 19.6 20.7 0.00021 19.6 14.3 2.4 1 1 1 2 2 2 1 Septation ring formation regulator, EzrA Gly-zipper_OmpA PF13436.1 XP_011275808.1 - 0.00074 19.1 40.9 0.021 14.4 0.2 6.1 6 0 0 6 6 5 3 Glycine-zipper containing OmpA-like membrane domain DUF2968 PF11180.3 XP_011275808.1 - 0.00074 18.9 18.1 0.00074 18.9 12.5 3.4 2 1 1 3 3 2 1 Protein of unknown function (DUF2968) EF-hand_8 PF13833.1 XP_011275808.1 - 0.0036 16.8 0.0 0.3 10.7 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain pair Romo1 PF10247.4 XP_011275808.1 - 0.61 10.3 10.4 17 5.7 0.8 4.0 4 0 0 4 4 4 0 Reactive mitochondrial oxygen species modulator 1 GAS PF13851.1 XP_011275808.1 - 0.94 8.6 62.8 0.039 13.1 14.5 4.0 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding DUF4200 PF13863.1 XP_011275808.1 - 6.4 6.7 65.6 0.73 9.7 8.4 4.4 1 1 3 4 4 4 0 Domain of unknown function (DUF4200) DUF3040 PF11239.3 XP_011275808.1 - 8.6 6.4 7.1 15 5.7 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3040) Nnf1 PF03980.9 XP_011275809.1 - 8.2e-15 54.7 3.5 8.2e-15 54.7 2.4 1.9 2 0 0 2 2 2 1 Nnf1 DUF3352 PF11832.3 XP_011275809.1 - 0.029 12.6 0.9 0.052 11.8 0.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3352) Guanylate_kin PF00625.16 XP_011275809.1 - 0.07 12.5 1.8 0.12 11.7 1.3 1.5 1 1 0 1 1 1 0 Guanylate kinase DUF2524 PF10732.4 XP_011275809.1 - 0.074 13.1 3.4 0.067 13.3 0.9 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2524) Cas_APE2256 PF09651.5 XP_011275809.1 - 0.093 12.4 0.2 0.11 12.2 0.1 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_APE2256) SNAP PF14938.1 XP_011275810.1 - 2.9e-98 328.5 14.6 3.3e-98 328.3 10.1 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 XP_011275810.1 - 1.3e-05 25.0 10.4 0.024 14.5 1.0 3.9 3 1 0 3 3 3 2 Tetratricopeptide repeat Spatacsin_C PF14649.1 XP_011275810.1 - 0.031 13.1 2.3 2.8 6.7 0.0 2.7 2 1 0 2 2 2 0 Spatacsin C-terminus Foie-gras_1 PF11817.3 XP_011275810.1 - 0.045 13.2 4.7 0.12 11.8 1.9 2.4 1 1 1 2 2 2 0 Foie gras liver health family 1 TPR_6 PF13174.1 XP_011275810.1 - 1.6 9.3 11.3 22 5.7 0.0 5.2 4 1 1 5 5 5 0 Tetratricopeptide repeat DUF2225 PF09986.4 XP_011275810.1 - 2.1 7.7 6.2 2.3 7.6 0.5 2.4 1 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_2 PF07719.12 XP_011275810.1 - 3.7 7.6 16.7 14 5.9 0.3 6.4 4 3 3 7 7 7 0 Tetratricopeptide repeat TPR_11 PF13414.1 XP_011275810.1 - 3.8 7.2 16.2 49 3.6 2.5 3.9 1 1 2 3 3 3 0 TPR repeat NSF PF02071.15 XP_011275810.1 - 6.9 7.7 15.3 2 9.3 0.1 6.3 8 0 0 8 8 8 0 Aromatic-di-Alanine (AdAR) repeat CPSase_L_D2 PF02786.12 XP_011275811.1 - 1.7e-109 364.0 0.2 4.3e-85 284.3 0.0 2.5 3 0 0 3 3 3 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 XP_011275811.1 - 4.2e-40 136.3 0.1 1.1e-39 134.9 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 XP_011275811.1 - 8.3e-36 123.4 0.3 5.7e-18 65.3 0.0 2.5 3 0 0 3 3 3 2 ATP-grasp domain CPSase_L_chain PF00289.17 XP_011275811.1 - 7.7e-35 119.3 0.0 4.8e-16 58.8 0.0 2.6 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 XP_011275811.1 - 1.2e-21 76.7 0.0 1.6e-07 30.3 0.0 3.6 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 XP_011275811.1 - 1.3e-20 73.4 0.0 3.8e-10 39.3 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 XP_011275811.1 - 4.2e-17 62.2 0.2 2.8e-07 30.1 0.0 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 XP_011275811.1 - 1.5e-10 40.8 0.0 3.6e-05 23.3 0.0 2.6 2 0 0 2 2 2 2 RimK-like ATP-grasp domain GARS_A PF01071.14 XP_011275811.1 - 5.3e-06 26.1 0.2 0.073 12.6 0.0 2.7 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_3 PF02655.9 XP_011275811.1 - 7.2e-05 22.7 0.1 0.31 10.8 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_5 PF13549.1 XP_011275811.1 - 0.0042 16.3 0.0 0.34 10.0 0.0 2.5 2 0 0 2 2 2 1 ATP-grasp domain G-alpha PF00503.15 XP_011275812.1 - 6.6e-112 374.0 16.2 8.3e-112 373.6 11.2 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 XP_011275812.1 - 1e-13 50.8 4.6 1.3e-10 40.8 0.0 2.8 3 0 0 3 3 3 2 ADP-ribosylation factor family Miro PF08477.8 XP_011275812.1 - 0.023 15.1 2.0 0.67 10.4 0.0 2.8 3 0 0 3 3 3 0 Miro-like protein AAA_29 PF13555.1 XP_011275812.1 - 0.034 13.6 0.1 0.08 12.4 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Gtr1_RagA PF04670.7 XP_011275812.1 - 0.41 9.7 7.5 1.2 8.1 0.0 2.6 3 0 0 3 3 3 0 Gtr1/RagA G protein conserved region Lipase_3 PF01764.20 XP_011275813.1 - 4.7e-35 120.2 0.0 6.9e-35 119.7 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 XP_011275813.1 - 1.4e-05 24.5 0.0 0.085 12.2 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2974) Abhydrolase_1 PF00561.15 XP_011275813.1 - 0.002 17.7 0.0 0.0032 17.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 XP_011275813.1 - 0.0092 15.7 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 XP_011275813.1 - 0.013 15.3 0.0 0.016 15.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.8 XP_011275813.1 - 0.061 12.9 0.1 0.12 11.9 0.0 1.5 1 1 0 1 1 1 0 PGAP1-like protein UPF0227 PF05728.7 XP_011275813.1 - 0.064 12.9 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) PMT PF02366.13 XP_011275814.1 - 3e-80 269.1 16.3 3e-80 269.1 11.3 2.1 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 XP_011275814.1 - 1.3e-52 178.1 2.0 2.5e-52 177.2 1.2 1.6 2 0 0 2 2 2 1 MIR domain NUDIX_4 PF14815.1 XP_011275814.1 - 0.091 12.1 0.8 0.22 10.9 0.4 1.7 1 1 0 1 1 1 0 NUDIX domain MFS_1 PF07690.11 XP_011275815.1 - 3.4e-17 62.1 27.2 3.9e-16 58.7 18.9 2.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Nodulin-like PF06813.8 XP_011275815.1 - 1.2e-15 57.4 5.3 1.2e-15 57.4 3.7 2.5 3 0 0 3 3 3 1 Nodulin-like SpoU_methylase PF00588.14 XP_011275816.1 - 4.9e-27 94.5 0.0 3e-26 91.9 0.0 2.2 2 0 0 2 2 2 1 SpoU rRNA Methylase family CTK3 PF12243.3 XP_011275816.1 - 0.0023 17.5 0.8 0.01 15.4 0.5 2.1 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 PX PF00787.19 XP_011275817.1 - 5.4e-23 80.9 0.3 1.4e-22 79.5 0.2 1.8 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 XP_011275817.1 - 6.3e-14 51.8 12.1 4.8e-07 29.2 0.5 2.2 2 0 0 2 2 2 2 Vps5 C terminal like BAR PF03114.13 XP_011275817.1 - 2.9e-06 26.9 0.6 2.9e-06 26.9 0.4 2.5 1 1 1 2 2 2 1 BAR domain KRTDAP PF15200.1 XP_011275817.1 - 0.083 12.6 0.1 0.47 10.2 0.0 2.4 1 0 0 1 1 1 0 Keratinocyte differentiation-associated SH3_1 PF00018.23 XP_011275818.1 - 3.8e-07 29.3 0.6 3.8e-07 29.3 0.4 1.9 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 XP_011275818.1 - 5.5e-07 29.0 0.2 1.6e-06 27.5 0.2 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 XP_011275818.1 - 7.1e-06 25.4 0.2 1.4e-05 24.4 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain EDR1 PF14381.1 XP_011275818.1 - 0.002 17.7 0.0 0.004 16.7 0.0 1.4 1 0 0 1 1 1 1 Ethylene-responsive protein kinase Le-CTR1 N_NLPC_P60 PF12912.2 XP_011275818.1 - 0.43 10.6 8.9 0.069 13.2 3.0 2.1 2 0 0 2 2 2 0 NLPC_P60 stabilising domain, N term Nup84_Nup100 PF04121.8 XP_011275819.1 - 2.5e-191 636.9 18.0 3.2e-191 636.6 12.5 1.1 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 PCI PF01399.22 XP_011275820.1 - 1e-15 57.9 1.5 3.6e-15 56.1 0.1 2.6 2 1 1 3 3 3 1 PCI domain TPR_16 PF13432.1 XP_011275820.1 - 3.3e-05 24.4 8.9 0.0036 17.9 2.8 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 XP_011275820.1 - 0.00053 20.2 13.7 1.2 9.5 1.7 5.2 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 XP_011275820.1 - 0.0029 17.5 12.9 0.12 12.3 1.9 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 XP_011275820.1 - 0.0062 17.0 6.6 19 6.2 0.0 4.8 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_8 PF13181.1 XP_011275820.1 - 0.0088 15.7 14.0 17 5.4 0.0 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat DDRGK PF09756.4 XP_011275820.1 - 0.036 13.4 0.2 0.036 13.4 0.1 2.6 2 1 0 3 3 3 0 DDRGK domain TPR_21 PF09976.4 XP_011275820.1 - 0.046 13.6 16.0 0.11 12.4 1.0 3.8 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 XP_011275820.1 - 0.079 12.6 13.5 1.6 8.4 0.0 4.8 4 1 1 5 5 5 0 TPR repeat TPR_7 PF13176.1 XP_011275820.1 - 0.088 12.6 9.2 7.9 6.5 0.1 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 XP_011275820.1 - 0.2 12.2 14.9 3.7 8.2 0.1 5.3 6 1 0 6 6 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 XP_011275820.1 - 0.21 11.5 13.8 6.4 6.9 0.0 5.9 7 0 0 7 7 6 0 Tetratricopeptide repeat Apc3 PF12895.2 XP_011275820.1 - 0.48 10.6 12.4 0.12 12.5 0.9 3.8 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 FIVAR PF07554.8 XP_011275820.1 - 7.7 6.8 13.0 20 5.5 0.5 4.6 4 0 0 4 4 4 0 Uncharacterised Sugar-binding Domain Nup35_RRM PF05172.8 XP_011275821.1 - 1.6e-30 104.7 0.0 3.2e-30 103.8 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 XP_011275821.1 - 1.6e-05 24.5 0.0 3e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF2418 PF10332.4 XP_011275822.1 - 7.5e-26 90.3 2.8 7.5e-26 90.3 1.9 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2418) Calpain_III PF01067.17 XP_011275823.1 - 1.2e-14 54.1 0.8 2.6e-13 49.8 0.0 2.6 2 0 0 2 2 2 1 Calpain large subunit, domain III Peptidase_C2 PF00648.16 XP_011275823.1 - 9.9e-12 44.4 0.1 2.2e-11 43.3 0.1 1.5 1 0 0 1 1 1 1 Calpain family cysteine protease Prenyltrans PF00432.16 XP_011275824.1 - 1.9e-44 148.8 10.4 1.8e-11 43.3 0.6 5.4 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 XP_011275824.1 - 1.7e-21 76.6 0.6 5.8e-16 58.9 0.2 3.3 2 1 1 3 3 3 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 XP_011275824.1 - 1.3e-07 31.6 0.2 0.0011 18.8 0.0 2.5 1 1 1 2 2 2 2 Prenyltransferase-like UBX PF00789.15 XP_011275825.1 - 1.4e-14 53.9 0.0 3.8e-14 52.4 0.0 1.8 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 XP_011275825.1 - 1.1e-10 40.8 0.0 1.8e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain PIG-L PF02585.12 XP_011275825.1 - 0.0094 16.4 0.0 0.018 15.5 0.0 1.5 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Protocadherin PF08374.6 XP_011275825.1 - 0.15 11.6 5.0 0.96 9.0 2.2 2.2 2 0 0 2 2 2 0 Protocadherin SRP14 PF02290.10 XP_011275826.1 - 3.9e-19 68.3 1.8 1e-18 67.0 1.3 1.6 1 1 0 1 1 1 1 Signal recognition particle 14kD protein Pkinase PF00069.20 XP_011275827.1 - 1.8e-65 220.6 0.0 3.1e-65 219.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011275827.1 - 6.1e-48 163.1 0.0 9.3e-48 162.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 XP_011275827.1 - 3.2e-05 23.0 0.0 0.00048 19.1 0.0 2.4 2 0 0 2 2 2 1 Kinase-like DUF3914 PF13053.1 XP_011275827.1 - 0.66 10.1 0.0 0.66 10.1 0.0 3.4 3 1 0 4 4 4 0 Protein of unknown function (DUF3914) Glyco_transf_15 PF01793.11 XP_011275829.1 - 5.6e-126 419.9 10.6 7.2e-126 419.6 7.4 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF843 PF05814.6 XP_011275829.1 - 0.19 11.5 1.1 0.38 10.5 0.8 1.4 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF843) HMG_box PF00505.14 XP_011275830.1 - 6e-19 68.0 0.6 1.2e-18 67.1 0.4 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 XP_011275830.1 - 1.2e-09 38.4 0.9 2.8e-09 37.1 0.1 2.1 2 0 0 2 2 2 1 HMG-box domain COX4 PF02936.9 XP_011275830.1 - 0.0054 16.4 1.0 0.012 15.3 0.7 1.5 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV WD40 PF00400.27 XP_011275832.1 - 3.7e-23 80.4 5.7 6.3e-07 29.0 0.0 4.9 5 0 0 5 5 5 4 WD domain, G-beta repeat IFT43 PF15305.1 XP_011275832.1 - 3 7.8 12.7 0.41 10.6 5.7 1.9 2 0 0 2 2 2 0 Intraflagellar transport protein 43 COG2 PF06148.6 XP_011275833.1 - 3.4e-24 85.2 4.5 4.9e-24 84.7 3.1 1.3 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.6 XP_011275833.1 - 0.003 17.3 3.1 0.0047 16.7 0.7 2.3 1 1 1 2 2 2 1 Vps51/Vps67 IncA PF04156.9 XP_011275833.1 - 0.008 15.7 2.1 0.014 15.0 1.5 1.4 1 0 0 1 1 1 1 IncA protein CAT PF00302.13 XP_011275833.1 - 0.012 15.2 0.2 0.017 14.7 0.1 1.2 1 0 0 1 1 1 0 Chloramphenicol acetyltransferase Mst1_SARAH PF11629.3 XP_011275833.1 - 0.032 14.0 0.7 0.11 12.2 0.5 2.0 1 0 0 1 1 1 0 C terminal SARAH domain of Mst1 DUF745 PF05335.8 XP_011275833.1 - 0.19 11.2 0.3 0.3 10.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Med2 PF11214.3 XP_011275833.1 - 0.22 11.5 3.8 0.48 10.4 2.2 2.0 2 1 0 2 2 2 0 Mediator complex subunit 2 Baculo_PEP_C PF04513.7 XP_011275833.1 - 0.4 10.5 6.4 5.2 6.8 0.3 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TMF_DNA_bd PF12329.3 XP_011275833.1 - 0.45 10.3 5.9 2.8 7.7 2.0 2.8 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Ribosomal_L29 PF00831.18 XP_011275833.1 - 1.2 8.8 4.3 0.86 9.3 0.8 2.2 2 0 0 2 2 2 0 Ribosomal L29 protein Pox_A_type_inc PF04508.7 XP_011275833.1 - 1.5 8.8 5.7 8.8 6.4 0.2 2.9 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat WD40 PF00400.27 XP_011275834.1 - 1.8e-08 33.9 0.7 0.0013 18.5 0.1 5.5 6 0 0 6 6 6 1 WD domain, G-beta repeat DUF3639 PF12341.3 XP_011275834.1 - 3.2e-08 33.4 4.0 4e-08 33.1 1.4 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3639) eIF2A PF08662.6 XP_011275834.1 - 5.2e-05 23.0 0.0 0.006 16.3 0.0 2.8 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 XP_011275834.1 - 0.0021 16.0 0.2 0.088 10.5 0.0 2.4 1 1 1 3 3 3 2 IKI3 family Apc4_WD40 PF12894.2 XP_011275834.1 - 0.042 13.3 0.0 1.3 8.6 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Strep_his_triad PF04270.8 XP_011275834.1 - 0.046 13.4 0.8 0.15 11.8 0.5 1.9 1 0 0 1 1 1 0 Streptococcal histidine triad protein DUF2076 PF09849.4 XP_011275834.1 - 2.2 8.2 7.2 4.8 7.1 5.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 XP_011275835.1 - 0.52 10.2 13.5 0.11 12.4 3.6 2.6 3 0 0 3 3 3 0 CHCH domain Cmc1 PF08583.5 XP_011275835.1 - 0.91 9.3 11.7 3.2 7.5 3.7 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 XP_011275835.1 - 2.2 8.3 9.2 84 3.3 6.4 2.8 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Nup54 PF13874.1 XP_011275836.1 - 5.6e-36 123.2 2.4 5.6e-36 123.2 1.6 2.9 2 1 1 3 3 3 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.1 XP_011275836.1 - 4.1e-20 72.1 128.0 1.1e-17 64.2 32.8 4.2 1 1 2 3 3 3 2 Nucleoporin FG repeat region DUF4116 PF13475.1 XP_011275836.1 - 0.016 14.6 0.5 0.033 13.6 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4116) Peptidase_M3_N PF08439.5 XP_011275836.1 - 0.081 12.9 0.1 0.28 11.2 0.0 1.9 1 0 0 1 1 1 0 Oligopeptidase F LicD PF04991.8 XP_011275838.1 - 1.1e-36 126.9 9.5 1.1e-36 126.9 6.6 2.3 2 0 0 2 2 2 1 LicD family Med26 PF08711.6 XP_011275839.1 - 1.1e-13 50.5 0.1 2.4e-13 49.3 0.1 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Pro-rich PF15240.1 XP_011275839.1 - 0.35 10.9 12.2 0.71 9.9 8.5 1.5 1 0 0 1 1 1 0 Proline-rich Ribosom_S12_S23 PF00164.20 XP_011275840.1 - 5.5e-40 135.5 0.6 7.1e-40 135.2 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S12/S23 WD40 PF00400.27 XP_011275841.1 - 0.00015 21.5 2.0 4 7.4 0.0 5.4 6 0 0 6 6 6 2 WD domain, G-beta repeat LisH PF08513.6 XP_011275841.1 - 0.0015 18.1 0.0 0.0037 16.9 0.0 1.7 1 0 0 1 1 1 1 LisH Mito_carr PF00153.22 XP_011275842.1 - 1.6e-58 194.4 0.1 1.1e-20 73.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Acetyltransf_1 PF00583.19 XP_011275843.1 - 5.5e-08 32.7 0.0 1e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 XP_011275843.1 - 8.2e-05 22.2 0.0 0.00014 21.5 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein LSM14 PF12701.2 XP_011275844.1 - 2.9e-19 68.6 2.6 9.8e-19 66.9 0.0 2.6 1 1 2 3 3 3 1 Scd6-like Sm domain FDF PF09532.5 XP_011275844.1 - 1.9e-05 25.1 11.8 1.9e-05 25.1 8.2 2.8 1 1 1 2 2 2 1 FDF domain PMC2NT PF08066.7 XP_011275844.1 - 0.042 14.1 0.5 0.092 13.0 0.4 1.6 1 0 0 1 1 1 0 PMC2NT (NUC016) domain Nucleo_P87 PF07267.6 XP_011275844.1 - 0.19 10.3 14.1 0.26 9.9 9.8 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 HSP70 PF00012.15 XP_011275844.1 - 0.44 8.3 3.6 0.6 7.9 2.5 1.1 1 0 0 1 1 1 0 Hsp70 protein Macoilin PF09726.4 XP_011275844.1 - 3.2 5.9 9.9 4 5.6 6.9 1.0 1 0 0 1 1 1 0 Transmembrane protein GRP PF07172.6 XP_011275844.1 - 9.5 6.7 16.7 0.8 10.2 7.4 2.0 2 0 0 2 2 2 0 Glycine rich protein family DUF1770 PF08589.5 XP_011275845.1 - 0.0013 19.3 0.1 0.0018 18.8 0.1 1.3 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) DUF2721 PF11026.3 XP_011275846.1 - 2.6e-05 23.8 0.1 3.8e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2721) RNA_pol_A_bac PF01000.21 XP_011275847.1 - 8.2e-31 106.4 0.2 1.3e-30 105.8 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 XP_011275847.1 - 4.8e-16 57.6 0.0 6.8e-16 57.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain His_biosynth PF00977.16 XP_011275848.1 - 9.9e-33 113.3 0.1 1.2e-32 113.0 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein Tmem26 PF09772.4 XP_011275848.1 - 0.061 12.5 0.0 0.09 11.9 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 26 Aldolase PF01081.14 XP_011275848.1 - 0.13 11.4 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 KDPG and KHG aldolase BUD22 PF09073.5 XP_011275849.1 - 1.6 7.7 20.8 2.4 7.1 14.4 1.2 1 0 0 1 1 1 0 BUD22 Glyco_hydro_16 PF00722.16 XP_011275850.1 - 5.8e-40 136.5 6.3 5.8e-40 136.5 4.4 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.14 XP_011275850.1 - 0.0028 17.6 13.5 0.0063 16.4 9.4 1.6 1 0 0 1 1 1 1 Chitin recognition protein DUF605 PF04652.11 XP_011275850.1 - 0.96 8.7 14.1 1.4 8.2 9.8 1.2 1 0 0 1 1 1 0 Vta1 like DNA_pol_viral_N PF00242.12 XP_011275850.1 - 2.6 6.9 10.8 3.7 6.4 7.5 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Med20 PF08612.6 XP_011275851.1 - 2.2e-34 118.5 0.0 2.2e-34 118.5 0.0 2.7 3 1 0 3 3 3 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex HLH PF00010.21 XP_011275851.1 - 8.3e-14 51.0 0.5 1.9e-13 49.8 0.4 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PMT PF02366.13 XP_011275852.1 - 4.6e-73 245.5 19.5 4.6e-73 245.5 13.5 1.8 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 XP_011275852.1 - 2.2e-24 86.0 3.4 4.3e-24 85.0 2.4 1.5 1 0 0 1 1 1 1 MIR domain BatD PF13584.1 XP_011275852.1 - 0.087 11.3 0.1 0.17 10.4 0.1 1.4 1 0 0 1 1 1 0 Oxygen tolerance Glyco_hydro_47 PF01532.15 XP_011275853.1 - 1.9e-152 508.0 0.4 2.4e-152 507.7 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF1680 PF07944.7 XP_011275853.1 - 0.021 13.1 0.0 1.4 7.1 0.0 2.6 2 1 0 2 2 2 0 Putative glycosyl hydrolase of unknown function (DUF1680) WD40 PF00400.27 XP_011275854.1 - 5.6e-60 197.2 13.1 2.4e-10 39.8 0.0 11.6 12 0 0 12 12 12 9 WD domain, G-beta repeat ILVD_EDD PF00920.16 XP_011275855.1 - 9.4e-204 677.6 1.1 1.1e-203 677.4 0.7 1.0 1 0 0 1 1 1 1 Dehydratase family Bot1p PF12298.3 XP_011275856.1 - 4e-46 157.1 3.9 5.8e-46 156.5 2.7 1.2 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein DUF2316 PF10078.4 XP_011275856.1 - 0.024 14.5 0.2 0.05 13.5 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2316) MOR2-PAG1_N PF14222.1 XP_011275857.1 - 1e-153 513.0 5.8 2.9e-153 511.5 4.0 1.9 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 XP_011275857.1 - 2.7e-87 292.8 1.8 2.7e-87 292.8 1.3 2.5 2 0 0 2 2 2 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 XP_011275857.1 - 8.8e-27 93.1 9.8 8.7e-12 43.5 0.1 4.4 2 2 1 3 3 3 3 Cell morphogenesis central region DUF917 PF06032.7 XP_011275858.1 - 9.8e-90 300.6 0.0 1.7e-89 299.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 XP_011275858.1 - 2.5e-51 174.4 1.9 7.3e-50 169.6 0.3 2.3 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 XP_011275858.1 - 3.9e-30 104.6 0.3 2e-29 102.3 0.0 2.4 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region Trs65 PF12735.2 XP_011275858.1 - 2.8e-26 92.5 12.2 2.8e-26 92.5 8.4 1.9 2 0 0 2 2 2 1 TRAPP trafficking subunit Trs65 BcrAD_BadFG PF01869.15 XP_011275858.1 - 0.0092 15.2 0.1 0.034 13.4 0.0 1.9 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family HEXIM PF15313.1 XP_011275858.1 - 0.39 10.8 1.9 0.78 9.9 0.3 2.0 2 0 0 2 2 2 0 Hexamethylene bis-acetamide-inducible protein Exo_endo_phos PF03372.18 XP_011275859.1 - 8.3e-12 45.5 0.0 6.9e-11 42.5 0.0 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RhoGAP PF00620.22 XP_011275859.1 - 0.002 17.7 0.7 0.0064 16.1 0.1 2.1 2 0 0 2 2 2 1 RhoGAP domain 3-HAO PF06052.7 XP_011275859.1 - 0.016 14.6 0.0 0.33 10.3 0.0 2.4 2 0 0 2 2 2 0 3-hydroxyanthranilic acid dioxygenase CDC45 PF02724.9 XP_011275859.1 - 4 5.3 10.6 8.2 4.3 7.3 1.4 1 0 0 1 1 1 0 CDC45-like protein Lung_7-TM_R PF06814.8 XP_011275861.1 - 2.4e-69 233.5 22.3 2.9e-69 233.2 15.5 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor zf-MYND PF01753.13 XP_011275862.1 - 8.8e-09 35.0 17.2 2.1e-08 33.8 12.0 1.7 1 1 0 1 1 1 1 MYND finger Mito_carr PF00153.22 XP_011275865.1 - 2.6e-60 200.1 5.0 3.2e-19 68.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.27 XP_011275866.1 - 1.2e-30 104.2 14.1 1.2e-09 37.6 0.1 7.2 6 2 0 6 6 6 6 WD domain, G-beta repeat eIF3g PF12353.3 XP_011275867.1 - 1.8e-38 131.3 7.2 1.9e-37 128.0 4.3 2.0 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 XP_011275867.1 - 2.6e-17 62.1 0.0 5.1e-17 61.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 XP_011275867.1 - 1.4e-11 44.1 0.0 3e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 XP_011275867.1 - 7.1e-10 38.5 0.0 1.4e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PCI PF01399.22 XP_011275868.1 - 1.1e-12 48.1 1.6 1.1e-12 48.1 1.1 2.4 2 1 1 3 3 3 1 PCI domain Abhydrolase_3 PF07859.8 XP_011275869.1 - 5.8e-12 45.6 0.0 8.8e-12 45.0 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 XP_011275869.1 - 1.4e-07 31.4 0.0 1.8e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 XP_011275869.1 - 1.3e-06 28.4 0.0 1.7e-06 28.0 0.0 1.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2305 PF10230.4 XP_011275869.1 - 0.0018 17.7 0.1 0.0029 17.0 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) LCAT PF02450.10 XP_011275869.1 - 0.0027 16.7 0.0 0.0054 15.7 0.0 1.4 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF2424 PF10340.4 XP_011275869.1 - 0.003 16.2 0.0 0.004 15.8 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 XP_011275869.1 - 0.0033 16.6 0.0 0.0056 15.9 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 XP_011275869.1 - 0.011 15.1 0.0 0.04 13.3 0.0 1.8 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF993 PF06187.6 XP_011275869.1 - 0.084 11.3 0.0 0.11 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF993) Lipase_2 PF01674.13 XP_011275869.1 - 0.1 11.8 0.0 0.27 10.5 0.0 1.6 2 0 0 2 2 2 0 Lipase (class 2) Kinesin PF00225.18 XP_011275870.1 - 1.4e-107 359.3 0.2 2e-107 358.7 0.2 1.3 1 0 0 1 1 1 1 Kinesin motor domain AAA_22 PF13401.1 XP_011275870.1 - 0.078 13.1 0.1 2.6 8.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain PX PF00787.19 XP_011275871.1 - 1.1e-19 70.2 3.1 1.8e-19 69.5 0.0 2.7 2 1 0 2 2 2 1 PX domain UBX PF00789.15 XP_011275872.1 - 4e-12 46.0 0.1 1.1e-11 44.5 0.0 1.8 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 XP_011275872.1 - 1.9e-10 40.0 0.2 4.5e-10 38.8 0.2 1.6 1 0 0 1 1 1 1 UBA-like domain AAA_12 PF13087.1 XP_011275873.1 - 5.5e-58 195.6 0.3 5.5e-58 195.6 0.2 2.1 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 XP_011275873.1 - 1.1e-40 139.6 0.6 1.1e-40 139.6 0.4 3.4 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 XP_011275873.1 - 3.7e-12 45.8 0.0 7.5e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 XP_011275873.1 - 3.4e-10 39.8 0.0 5.8e-09 35.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 XP_011275873.1 - 1.7e-08 34.3 0.5 0.015 14.8 0.0 4.1 4 0 0 4 4 4 3 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.1 XP_011275873.1 - 5.5e-05 23.2 0.0 0.00018 21.6 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain DUF258 PF03193.11 XP_011275873.1 - 0.0012 18.0 0.5 0.0033 16.6 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ResIII PF04851.10 XP_011275873.1 - 0.0015 18.3 0.2 0.0015 18.3 0.1 3.0 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_16 PF13191.1 XP_011275873.1 - 0.0016 18.4 0.0 0.033 14.1 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 XP_011275873.1 - 0.0019 18.4 0.0 0.009 16.2 0.0 2.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 XP_011275873.1 - 0.0027 17.8 0.0 0.011 15.8 0.0 2.1 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 XP_011275873.1 - 0.0065 15.9 0.1 0.02 14.3 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_RecD PF05127.9 XP_011275873.1 - 0.0078 15.8 0.1 0.036 13.6 0.0 2.3 3 0 0 3 3 2 1 Helicase MobB PF03205.9 XP_011275873.1 - 0.0098 15.5 0.1 0.077 12.7 0.0 2.3 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 XP_011275873.1 - 0.025 13.9 0.1 0.061 12.7 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain zf-UBP PF02148.14 XP_011275873.1 - 0.84 9.7 9.6 0.47 10.5 0.6 2.9 2 0 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein MARVEL PF01284.18 XP_011275874.1 - 9e-05 22.3 3.6 0.00018 21.3 2.5 1.5 1 0 0 1 1 1 1 Membrane-associating domain DUF1430 PF07242.6 XP_011275874.1 - 2 8.5 7.2 0.62 10.1 1.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1430) Mit_KHE1 PF10173.4 XP_011275875.1 - 1.7e-55 187.7 0.5 2.2e-55 187.3 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related DUF3105 PF11303.3 XP_011275875.1 - 0.15 11.8 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3105) ATP-synt_ab PF00006.20 XP_011275876.1 - 9.5e-117 388.0 0.0 1.4e-116 387.4 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 XP_011275876.1 - 1.5e-18 67.3 0.1 3.1e-18 66.2 0.1 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 XP_011275876.1 - 5.3e-16 58.5 1.8 1.3e-15 57.3 1.3 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA_14 PF13173.1 XP_011275876.1 - 0.046 13.6 0.0 0.17 11.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain MFS_1 PF07690.11 XP_011275878.1 - 5.1e-31 107.6 30.8 5.2e-31 107.6 20.6 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 XP_011275878.1 - 4.5e-07 28.6 20.9 1.6e-06 26.8 14.3 2.0 1 1 1 2 2 2 1 MFS/sugar transport protein tRNA_SAD PF07973.9 XP_011275879.1 - 4.5e-09 36.0 0.1 9.8e-09 34.9 0.1 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.14 XP_011275879.1 - 6e-08 31.4 1.0 1.1e-07 30.5 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class II (A) TF_Zn_Ribbon PF08271.7 XP_011275880.1 - 0.03 13.6 0.5 0.081 12.2 0.4 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding Lge1 PF11488.3 XP_011275881.1 - 2.3e-05 24.5 8.2 5.7e-05 23.2 5.7 1.8 1 1 0 1 1 1 1 Transcriptional regulatory protein LGE1 ECH_C PF13766.1 XP_011275882.1 - 1.5e-30 105.7 0.1 3.3e-30 104.6 0.1 1.6 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 XP_011275882.1 - 3.9e-26 91.6 0.0 1.3e-25 89.9 0.0 1.9 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF3211 PF11485.3 XP_011275883.1 - 0.082 12.9 0.1 0.25 11.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3211) COesterase PF00135.23 XP_011275884.1 - 6.9e-101 338.5 0.1 9.1e-101 338.1 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 XP_011275884.1 - 0.0044 16.6 0.6 0.013 15.1 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 XP_011275884.1 - 0.048 12.8 0.1 0.21 10.8 0.0 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase family LRR_6 PF13516.1 XP_011275885.1 - 0.45 10.7 17.0 4.2 7.7 0.0 5.3 4 1 1 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.28 XP_011275885.1 - 0.65 10.2 10.9 10 6.5 0.3 5.4 4 1 0 4 4 4 0 Leucine Rich Repeat DUF605 PF04652.11 XP_011275885.1 - 1 8.6 15.1 1.5 8.1 10.5 1.2 1 0 0 1 1 1 0 Vta1 like Myb_DNA-binding PF00249.26 XP_011275886.1 - 2.7e-10 40.1 0.1 1.2e-05 25.2 0.0 3.6 4 0 0 4 4 4 2 Myb-like DNA-binding domain ELO PF01151.13 XP_011275887.1 - 9.2e-60 202.0 25.0 9.2e-60 202.0 17.3 1.7 1 1 1 2 2 2 1 GNS1/SUR4 family Chordopox_E11 PF06138.7 XP_011275887.1 - 0.063 13.3 0.8 0.14 12.2 0.1 1.9 2 0 0 2 2 2 0 Chordopoxvirus E11 protein DUF2334 PF10096.4 XP_011275887.1 - 0.13 11.6 0.1 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) RNase_PH PF01138.16 XP_011275888.1 - 1.7e-22 80.1 0.1 9.9e-22 77.6 0.0 2.3 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 Glyco_hydro_17 PF00332.13 XP_011275889.1 - 0.07 12.1 0.0 0.092 11.7 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 FAM60A PF15396.1 XP_011275891.1 - 0.0012 18.5 2.8 0.0019 17.9 1.9 1.3 1 0 0 1 1 1 1 Protein Family FAM60A Pex14_N PF04695.8 XP_011275891.1 - 0.0069 16.4 7.5 0.012 15.7 5.2 1.3 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region RP-C_C PF11800.3 XP_011275891.1 - 0.029 14.0 14.3 0.037 13.7 9.5 1.4 1 1 0 1 1 1 0 Replication protein C C-terminal region DUF2407_C PF13373.1 XP_011275891.1 - 0.05 13.5 4.1 0.1 12.5 2.8 1.5 1 0 0 1 1 1 0 DUF2407 C-terminal domain DUF2370 PF10176.4 XP_011275891.1 - 0.059 12.6 4.1 0.094 12.0 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) AUX_IAA PF02309.11 XP_011275891.1 - 0.071 12.8 5.1 0.11 12.2 3.5 1.2 1 0 0 1 1 1 0 AUX/IAA family DUF4337 PF14235.1 XP_011275891.1 - 0.084 12.7 4.9 0.16 11.7 3.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) BaxI_1 PF12811.2 XP_011275891.1 - 0.13 11.4 1.5 0.19 10.8 1.0 1.2 1 0 0 1 1 1 0 Bax inhibitor 1 like Podoplanin PF05808.6 XP_011275891.1 - 0.15 11.6 0.2 0.63 9.5 0.0 1.9 1 1 1 2 2 2 0 Podoplanin TRP PF06011.7 XP_011275891.1 - 0.62 8.5 3.9 0.35 9.3 1.5 1.3 2 0 0 2 2 2 0 Transient receptor potential (TRP) ion channel Neur_chan_memb PF02932.11 XP_011275891.1 - 0.76 9.6 6.3 0.68 9.7 3.7 1.5 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF2254 PF10011.4 XP_011275891.1 - 4 5.8 14.0 0.069 11.6 0.2 2.2 1 1 1 2 2 2 0 Predicted membrane protein (DUF2254) Zip PF02535.17 XP_011275891.1 - 5.5 5.9 15.0 0.44 9.4 7.2 1.5 2 0 0 2 2 2 0 ZIP Zinc transporter OmpH PF03938.9 XP_011275891.1 - 5.7 6.8 19.4 9.9 6.0 13.5 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) PfkB PF00294.19 XP_011275892.1 - 1.8e-53 181.6 1.0 2.3e-53 181.3 0.7 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase UCH PF00443.24 XP_011275893.1 - 3.5e-82 275.5 0.0 3.1e-80 269.1 0.0 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 XP_011275893.1 - 4.3e-20 72.3 2.2 1.5e-12 47.6 0.2 2.7 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase SPX PF03105.14 XP_011275894.1 - 5.6e-42 144.4 32.8 5.6e-42 144.4 22.7 1.8 1 1 1 2 2 2 1 SPX domain Na_sulph_symp PF00939.14 XP_011275894.1 - 2.4e-23 82.7 45.7 3.7e-23 82.1 31.7 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 XP_011275894.1 - 1.1e-11 43.9 23.9 1.1e-11 43.9 16.5 2.2 1 1 1 2 2 2 2 Citrate transporter LRR_8 PF13855.1 XP_011275895.1 - 0.89 9.3 17.6 0.49 10.1 0.8 5.5 4 2 2 6 6 6 0 Leucine rich repeat LRR_4 PF12799.2 XP_011275895.1 - 5.4 6.7 20.4 16 5.2 0.0 5.7 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) F-box PF00646.28 XP_011275897.1 - 0.0009 18.8 0.4 0.0019 17.7 0.3 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 XP_011275897.1 - 0.042 13.5 0.1 0.087 12.5 0.0 1.5 1 0 0 1 1 1 0 F-box-like Acetyltransf_7 PF13508.1 XP_011275898.1 - 4.3e-08 33.2 0.0 1.2e-07 31.7 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 XP_011275898.1 - 5.1e-05 23.1 0.0 0.00014 21.6 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 XP_011275898.1 - 6.4e-05 22.9 0.0 0.00017 21.5 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family AdoHcyase_NAD PF00670.16 XP_011275899.1 - 0.027 14.3 0.0 0.046 13.5 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Acetyltransf_9 PF13527.1 XP_011275900.1 - 2.4e-06 27.3 0.0 5.5e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 XP_011275900.1 - 7.3e-06 26.0 0.1 2.8e-05 24.2 0.0 2.1 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 XP_011275900.1 - 0.0012 18.8 0.0 0.0046 16.9 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.5 XP_011275900.1 - 0.027 14.2 0.0 0.059 13.1 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein DUF2989 PF11207.3 XP_011275900.1 - 0.046 13.1 0.5 0.11 11.9 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2989) 2OG-FeII_Oxy_2 PF13532.1 XP_011275902.1 - 8.4e-21 74.6 0.3 1.5e-20 73.9 0.1 1.4 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 XP_011275902.1 - 0.0023 18.2 0.1 0.006 16.8 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily CUE PF02845.11 XP_011275902.1 - 0.018 14.5 0.1 0.091 12.2 0.0 2.3 3 0 0 3 3 3 0 CUE domain Zn_ribbon_recom PF13408.1 XP_011275902.1 - 3.3 8.0 9.5 0.13 12.5 2.0 2.0 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Aldo_ket_red PF00248.16 XP_011275903.1 - 2.5e-50 170.8 0.0 3.2e-50 170.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family PBP PF01161.15 XP_011275904.1 - 2e-16 60.1 0.1 5.3e-16 58.7 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein ATG_C PF09333.6 XP_011275904.1 - 0.043 13.9 0.0 0.083 13.0 0.0 1.4 1 0 0 1 1 1 0 ATG C terminal domain P2 PF07194.6 XP_011275904.1 - 0.9 9.4 3.9 83 3.1 0.0 4.1 5 0 0 5 5 5 0 P2 response regulator binding domain ATP-synt_E PF05680.7 XP_011275905.1 - 2.8e-19 68.8 0.8 3e-19 68.7 0.5 1.0 1 0 0 1 1 1 1 ATP synthase E chain SpoIIE PF07228.7 XP_011275906.1 - 7.8e-25 87.7 0.0 1.1e-24 87.2 0.0 1.2 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 XP_011275906.1 - 5.2e-06 26.0 0.0 1.2e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 XP_011275906.1 - 4.8e-05 22.8 0.3 0.018 14.4 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C MIF4G PF02854.14 XP_011275907.1 - 1.5e-27 96.3 34.8 4.9e-13 48.9 3.8 3.8 3 1 0 3 3 3 3 MIF4G domain Upf2 PF04050.9 XP_011275907.1 - 5.6e-09 35.9 57.1 9.9e-09 35.1 35.3 3.3 2 1 0 2 2 2 1 Up-frameshift suppressor 2 CDC45 PF02724.9 XP_011275907.1 - 0.013 13.5 19.7 0.026 12.5 13.6 1.4 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 XP_011275907.1 - 2 6.7 40.1 0.01 14.3 21.2 1.8 3 0 0 3 3 3 0 Daxx Family FYVE PF01363.16 XP_011275908.1 - 3.7e-18 65.1 26.6 1.1e-14 54.0 2.6 3.1 3 0 0 3 3 3 2 FYVE zinc finger zf-AN1 PF01428.11 XP_011275908.1 - 0.0058 16.4 5.7 0.0058 16.4 4.0 4.1 5 1 0 5 5 5 1 AN1-like Zinc finger ORC5_C PF14630.1 XP_011275909.1 - 7.9e-61 205.8 7.2 1.1e-60 205.3 5.0 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_22 PF13401.1 XP_011275909.1 - 9.7e-09 35.4 0.0 1.9e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 XP_011275909.1 - 1.4e-06 28.3 0.0 1e-05 25.6 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain CDC45 PF02724.9 XP_011275909.1 - 0.00037 18.6 2.6 0.00049 18.2 1.8 1.1 1 0 0 1 1 1 1 CDC45-like protein DUF2457 PF10446.4 XP_011275909.1 - 0.0053 15.5 6.8 0.0072 15.1 4.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) AAA PF00004.24 XP_011275909.1 - 0.029 14.5 0.0 0.07 13.3 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 XP_011275909.1 - 0.076 13.8 3.6 0.11 13.3 0.0 2.5 2 1 0 2 2 2 0 AAA domain CobT PF06213.7 XP_011275909.1 - 0.14 11.2 8.8 0.21 10.7 6.1 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT TRAP_alpha PF03896.11 XP_011275909.1 - 0.15 11.0 5.2 0.25 10.3 3.6 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Daxx PF03344.10 XP_011275909.1 - 0.53 8.6 10.1 0.76 8.1 7.0 1.1 1 0 0 1 1 1 0 Daxx Family NOA36 PF06524.7 XP_011275909.1 - 0.62 9.2 6.8 0.95 8.6 4.7 1.2 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.5 XP_011275909.1 - 0.75 10.0 10.3 1.9 8.8 7.2 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain YqfQ PF14181.1 XP_011275909.1 - 2.4 8.1 8.2 4.1 7.4 5.7 1.3 1 0 0 1 1 1 0 YqfQ-like protein Prog_receptor PF02161.10 XP_011275909.1 - 3.8 6.2 7.3 5.2 5.7 5.0 1.1 1 0 0 1 1 1 0 Progesterone receptor GYF PF02213.11 XP_011275910.1 - 5e-12 45.2 2.7 1.7e-11 43.5 1.9 2.0 1 0 0 1 1 1 1 GYF domain z-alpha PF02295.12 XP_011275910.1 - 0.027 14.2 1.0 0.086 12.6 0.7 1.9 1 0 0 1 1 1 0 Adenosine deaminase z-alpha domain WD40 PF00400.27 XP_011275912.1 - 8.6e-08 31.7 1.0 2.3e-06 27.2 0.2 3.1 3 0 0 3 3 3 1 WD domain, G-beta repeat DUF2415 PF10313.4 XP_011275912.1 - 0.00099 18.7 0.0 0.0039 16.8 0.0 2.1 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) Mga PF05043.8 XP_011275912.1 - 0.0022 18.2 0.6 0.014 15.6 0.1 2.5 2 0 0 2 2 2 1 Mga helix-turn-helix domain HMA PF00403.21 XP_011275913.1 - 2.2e-10 40.5 0.2 2.6e-10 40.3 0.1 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain Pro_isomerase PF00160.16 XP_011275914.1 - 1.2e-17 64.5 0.1 1.2e-17 64.5 0.0 1.6 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Zip PF02535.17 XP_011275914.1 - 0.022 13.7 7.4 0.027 13.4 5.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter PH PF00169.24 XP_011275915.1 - 2.4e-09 37.3 0.8 1.3e-08 34.9 0.1 2.7 2 0 0 2 2 2 1 PH domain UPF0086 PF01868.11 XP_011275915.1 - 0.056 13.0 0.0 1.2 8.8 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function UPF0086 PGAP1 PF07819.8 XP_011275916.1 - 2e-06 27.5 0.0 5.3e-06 26.1 0.0 1.7 2 0 0 2 2 2 1 PGAP1-like protein DUF676 PF05057.9 XP_011275916.1 - 2.9e-06 26.7 0.0 5.8e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF915 PF06028.6 XP_011275916.1 - 0.00028 20.0 0.1 0.00071 18.7 0.1 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) LCAT PF02450.10 XP_011275916.1 - 0.00088 18.3 0.0 0.0016 17.5 0.0 1.4 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF900 PF05990.7 XP_011275916.1 - 0.011 15.1 0.0 0.02 14.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_5 PF12695.2 XP_011275916.1 - 0.044 13.5 0.0 0.098 12.4 0.0 1.7 2 1 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 XP_011275916.1 - 0.056 12.9 0.0 0.09 12.3 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2605 PF10792.4 XP_011275916.1 - 0.14 11.8 0.1 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2605) RRM_1 PF00076.17 XP_011275917.1 - 1.8e-15 56.2 0.0 2.9e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 XP_011275917.1 - 7.1e-11 41.9 0.0 1.1e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 XP_011275917.1 - 2.6e-08 33.5 0.1 4.3e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAD_binding_3 PF01494.14 XP_011275918.1 - 2e-28 99.4 0.0 1.2e-16 60.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 XP_011275918.1 - 2.3e-07 30.0 0.0 0.047 12.6 0.0 3.0 3 0 0 3 3 3 2 Lycopene cyclase protein NAD_binding_9 PF13454.1 XP_011275918.1 - 0.0014 18.3 0.0 0.016 14.9 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Trp_halogenase PF04820.9 XP_011275918.1 - 0.0045 15.6 0.1 0.54 8.8 0.0 2.9 3 0 0 3 3 3 1 Tryptophan halogenase Pyr_redox_3 PF13738.1 XP_011275918.1 - 0.0056 16.7 0.2 0.057 13.4 0.2 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 XP_011275918.1 - 0.01 15.7 0.1 0.041 13.7 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DUF3969 PF13108.1 XP_011275918.1 - 0.019 14.6 1.6 0.036 13.7 0.2 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3969) SE PF08491.5 XP_011275918.1 - 0.028 13.2 0.0 0.046 12.5 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase Pyr_redox PF00070.22 XP_011275918.1 - 0.033 14.5 0.2 11 6.5 0.0 2.8 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 XP_011275918.1 - 0.042 12.7 0.0 3.8 6.3 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.9 XP_011275918.1 - 0.045 12.2 0.0 0.66 8.3 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein Mqo PF06039.10 XP_011275918.1 - 0.066 11.3 1.5 2.5 6.1 0.0 2.5 3 0 0 3 3 3 0 Malate:quinone oxidoreductase (Mqo) K_oxygenase PF13434.1 XP_011275918.1 - 0.069 12.0 0.8 7.1 5.4 0.1 2.3 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 XP_011275918.1 - 0.12 12.4 0.1 0.36 10.8 0.0 1.9 2 0 0 2 2 1 0 NAD(P)-binding Rossmann-like domain Pterin_bind PF00809.17 XP_011275919.1 - 4.8e-58 195.9 0.0 1.8e-43 148.3 0.0 2.5 1 1 1 2 2 2 2 Pterin binding enzyme FolB PF02152.13 XP_011275919.1 - 6e-42 142.3 5.3 6.7e-21 74.5 0.5 2.8 3 0 0 3 3 3 2 Dihydroneopterin aldolase HPPK PF01288.15 XP_011275919.1 - 1.7e-40 137.6 0.0 5.2e-40 136.1 0.0 1.9 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) zf-CCHC PF00098.18 XP_011275920.1 - 1.3e-41 138.5 57.2 4e-07 29.6 1.9 7.8 7 1 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 XP_011275920.1 - 5.5e-08 32.3 43.4 0.16 11.6 0.9 7.1 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_3 PF13917.1 XP_011275920.1 - 0.0004 20.0 51.3 0.0041 16.8 2.1 6.8 2 2 3 5 5 5 3 Zinc knuckle zf-CCHC_6 PF15288.1 XP_011275920.1 - 0.045 13.4 0.1 0.045 13.4 0.1 6.9 7 0 0 7 7 7 0 Zinc knuckle zf-CCHC_2 PF13696.1 XP_011275920.1 - 0.41 10.1 40.4 0.26 10.8 0.9 6.9 5 1 2 7 7 7 0 Zinc knuckle SIT PF15330.1 XP_011275920.1 - 6.5 6.9 6.3 11 6.1 2.1 2.4 1 1 1 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT RTC4 PF14474.1 XP_011275921.1 - 2.5e-26 92.0 0.7 4.1e-26 91.3 0.0 1.8 2 0 0 2 2 2 1 RTC4-like domain WD40 PF00400.27 XP_011275922.1 - 6.8e-19 66.9 1.3 5.3e-05 22.9 0.0 5.5 6 0 0 6 6 6 4 WD domain, G-beta repeat Apc4_WD40 PF12894.2 XP_011275922.1 - 5.7e-05 22.5 0.5 1.6 8.2 0.0 4.2 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.3 XP_011275922.1 - 0.0014 16.9 0.7 0.0033 15.6 0.1 1.8 1 1 1 2 2 2 1 Nucleoporin Nup120/160 IKI3 PF04762.7 XP_011275922.1 - 0.0032 15.3 1.5 0.065 11.0 0.4 1.9 1 1 1 2 2 2 1 IKI3 family Cytochrom_D1 PF02239.11 XP_011275922.1 - 0.0043 15.4 0.4 0.17 10.1 0.1 2.7 1 1 1 3 3 3 2 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 XP_011275922.1 - 0.088 11.5 4.9 1.8 7.2 1.0 2.8 1 1 2 3 3 3 0 Nup133 N terminal like W_rich_C PF07483.6 XP_011275922.1 - 0.11 12.2 1.9 0.27 10.9 0.5 2.2 2 0 0 2 2 2 0 Tryptophan-rich Synechocystis species C-terminal domain DUF503 PF04456.7 XP_011275922.1 - 0.11 12.0 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF503) MRP-L46 PF11788.3 XP_011275923.1 - 2.8e-33 114.8 0.5 4.5e-33 114.2 0.3 1.3 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 DUF4065 PF13274.1 XP_011275923.1 - 0.069 13.8 0.4 0.25 12.0 0.0 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF4065) tRNA-synt_1e PF01406.14 XP_011275924.1 - 6.4e-140 465.5 0.7 6.4e-140 465.5 0.5 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 XP_011275924.1 - 1.4e-06 27.2 0.1 1.4e-06 27.2 0.1 2.7 3 0 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 XP_011275924.1 - 1.5e-05 23.2 3.6 2e-05 22.8 0.0 2.6 3 0 0 3 3 3 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.13 XP_011275924.1 - 2.5e-05 23.1 1.6 0.0001 21.0 0.1 2.4 2 1 0 2 2 2 1 tRNA synthetases class I (K) DUF972 PF06156.8 XP_011275924.1 - 0.2 12.0 0.1 0.2 12.0 0.1 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF972) SbcCD_C PF13558.1 XP_011275925.1 - 2.6e-11 43.2 0.0 8e-11 41.7 0.0 1.9 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit Rad50_zn_hook PF04423.9 XP_011275925.1 - 2.1e-07 30.2 0.4 2.1e-07 30.2 0.3 6.2 5 1 1 6 6 6 1 Rad50 zinc hook motif NPV_P10 PF05531.7 XP_011275925.1 - 0.039 14.2 0.5 0.039 14.2 0.3 10.7 4 4 4 9 9 9 0 Nucleopolyhedrovirus P10 protein AAA_13 PF13166.1 XP_011275925.1 - 0.042 12.3 148.2 0.057 11.8 19.6 6.5 1 1 4 5 5 5 0 AAA domain Reo_sigmaC PF04582.7 XP_011275925.1 - 0.27 10.3 63.5 0.09 11.9 4.4 7.9 3 2 6 10 10 10 0 Reovirus sigma C capsid protein Chorion_3 PF05387.6 XP_011275925.1 - 0.69 9.3 3.3 0.65 9.3 1.0 1.9 2 0 0 2 2 2 0 Chorion family 3 FGGY_C PF02782.11 XP_011275926.1 - 1.3e-31 109.7 0.0 1.9e-31 109.2 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 XP_011275926.1 - 5.4e-15 55.3 0.5 3.4e-14 52.7 0.3 1.9 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 XP_011275926.1 - 0.05 12.8 0.3 2.8 7.1 0.0 2.3 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Abhydrolase_6 PF12697.2 XP_011275927.1 - 2.7e-07 30.7 0.0 7.7e-07 29.2 0.0 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 XP_011275927.1 - 3.1e-05 23.6 0.0 6.7e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold LCAT PF02450.10 XP_011275927.1 - 0.00012 21.1 0.1 0.0003 19.8 0.1 1.7 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_5 PF12695.2 XP_011275927.1 - 0.003 17.3 0.0 0.0066 16.2 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 XP_011275927.1 - 0.0056 16.2 0.2 0.018 14.6 0.0 1.8 2 0 0 2 2 2 1 PGAP1-like protein DUF900 PF05990.7 XP_011275927.1 - 0.018 14.3 0.0 0.034 13.4 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_8 PF06259.7 XP_011275927.1 - 0.028 13.9 0.0 0.051 13.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase zf-CSL PF05207.8 XP_011275928.1 - 1.2e-16 59.8 0.1 2.3e-16 59.0 0.1 1.5 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.26 XP_011275928.1 - 8.4e-16 57.4 1.1 1.2e-15 56.9 0.8 1.2 1 0 0 1 1 1 1 DnaJ domain Lar_restr_allev PF14354.1 XP_011275928.1 - 0.011 16.0 0.2 0.021 15.1 0.1 1.4 1 0 0 1 1 1 0 Restriction alleviation protein Lar RNA_pol_I_A49 PF06870.7 XP_011275929.1 - 2.9e-129 431.0 0.1 3.2e-129 430.8 0.1 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Peptidase_U4 PF03419.8 XP_011275929.1 - 0.14 11.2 0.1 0.19 10.7 0.1 1.2 1 0 0 1 1 1 0 Sporulation factor SpoIIGA NAP PF00956.13 XP_011275931.1 - 3.2e-22 78.8 9.0 5.5e-22 78.0 6.3 1.3 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) UPF0240 PF06784.6 XP_011275931.1 - 0.014 15.0 0.2 0.051 13.2 0.0 1.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0240) BNR PF02012.15 XP_011275932.1 - 8.6e-07 27.8 30.5 1.2 9.2 0.0 9.5 9 0 0 9 9 9 5 BNR/Asp-box repeat BNR_2 PF13088.1 XP_011275932.1 - 4e-05 23.0 7.1 0.00039 19.7 0.0 4.6 5 1 0 5 5 5 1 BNR repeat-like domain DUF2167 PF09935.4 XP_011275932.1 - 0.024 13.4 0.6 0.4 9.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2167) Cys_knot PF00007.17 XP_011275932.1 - 1.6 8.8 9.2 0.53 10.3 0.3 2.8 2 1 0 2 2 2 0 Cystine-knot domain Cir_N PF10197.4 XP_011275933.1 - 9.7e-17 60.7 9.6 9.7e-17 60.7 6.7 3.4 3 0 0 3 3 3 1 N-terminal domain of CBF1 interacting co-repressor CIR CWC25 PF12542.3 XP_011275933.1 - 1.3e-16 60.7 4.6 1.3e-16 60.7 3.2 4.4 1 1 2 3 3 3 1 Pre-mRNA splicing factor SUI1 PF01253.17 XP_011275934.1 - 9.3e-31 105.4 1.0 1.2e-30 105.1 0.7 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 Cas_Csa5 PF09702.5 XP_011275934.1 - 0.14 12.2 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csa5) ANTH PF07651.11 XP_011275935.1 - 1.2e-73 247.2 0.0 1.2e-73 247.2 0.0 3.0 3 1 0 3 3 3 1 ANTH domain I_LWEQ PF01608.12 XP_011275935.1 - 8.2e-64 214.1 6.1 8.2e-64 214.1 4.2 4.9 5 1 0 5 5 5 1 I/LWEQ domain ENTH PF01417.15 XP_011275935.1 - 2.8e-05 23.9 0.0 0.00017 21.4 0.0 2.5 1 0 0 1 1 1 1 ENTH domain Med15 PF09606.5 XP_011275935.1 - 9.7 4.2 42.6 17 3.4 29.5 1.4 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Homeobox PF00046.24 XP_011275936.1 - 7.1e-11 41.5 0.9 2.6e-10 39.7 0.1 2.2 2 0 0 2 2 2 1 Homeobox domain DUF327 PF03885.8 XP_011275936.1 - 8.8 6.1 10.5 0.56 10.0 2.3 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF327) DUF3452 PF11934.3 XP_011275938.1 - 2.2 7.6 7.1 6.6 6.0 0.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3452) Mito_carr PF00153.22 XP_011275939.1 - 1.3e-56 188.2 0.1 1.6e-18 66.1 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Zn_clus PF00172.13 XP_011275940.1 - 1.1e-07 31.6 10.4 2.2e-07 30.6 7.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 XP_011275944.1 - 7.9e-07 28.7 6.6 0.038 13.8 0.0 5.6 6 1 0 6 6 6 3 WD domain, G-beta repeat Pox_A_type_inc PF04508.7 XP_011275945.1 - 0.045 13.5 0.5 0.045 13.5 0.3 4.1 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat Rox3 PF08633.5 XP_011275946.1 - 0.0033 17.7 4.8 0.0064 16.8 3.3 1.5 1 0 0 1 1 1 1 Rox3 mediator complex subunit SRP54 PF00448.17 XP_011275947.1 - 1.1e-78 263.1 0.8 1.7e-78 262.5 0.2 1.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 XP_011275947.1 - 1.9e-26 92.3 10.7 1.9e-26 92.3 7.4 3.9 3 1 1 4 4 4 1 Signal peptide binding domain SRP54_N PF02881.14 XP_011275947.1 - 3.6e-16 59.0 3.2 8.6e-16 57.8 2.2 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_33 PF13671.1 XP_011275947.1 - 6.1e-06 26.1 0.0 1.4e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain cobW PF02492.14 XP_011275947.1 - 1.3e-05 24.6 1.1 6.9e-05 22.3 0.2 2.5 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain CbiA PF01656.18 XP_011275947.1 - 2.7e-05 23.6 0.1 9.4e-05 21.8 0.1 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 XP_011275947.1 - 0.00013 21.9 0.0 0.032 14.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 XP_011275947.1 - 0.0002 20.2 0.1 0.00074 18.3 0.1 2.0 1 1 0 1 1 1 1 ArgK protein MobB PF03205.9 XP_011275947.1 - 0.00047 19.8 2.1 0.00072 19.2 0.0 2.3 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 XP_011275947.1 - 0.0025 18.6 0.0 0.0053 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 XP_011275947.1 - 0.0026 17.2 0.1 0.0038 16.7 0.1 1.3 1 0 0 1 1 1 1 AAA-like domain APS_kinase PF01583.15 XP_011275947.1 - 0.007 16.0 0.0 0.016 14.8 0.0 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_30 PF13604.1 XP_011275947.1 - 0.029 13.9 0.0 0.055 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.5 XP_011275947.1 - 0.035 13.3 0.3 7.6 5.7 0.0 3.2 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 XP_011275947.1 - 0.035 14.2 0.5 0.13 12.3 0.1 2.4 2 1 0 2 2 2 0 AAA domain MipZ PF09140.6 XP_011275947.1 - 0.071 12.1 0.1 1.1 8.2 0.1 2.3 1 1 0 1 1 1 0 ATPase MipZ AAA_16 PF13191.1 XP_011275947.1 - 0.079 12.9 0.0 0.21 11.5 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.7 XP_011275947.1 - 0.085 11.9 0.0 0.18 10.8 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA PF00004.24 XP_011275947.1 - 0.22 11.7 2.4 1.2 9.3 0.4 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF1712 PF08217.6 XP_011275948.1 - 2.3e-28 98.8 20.1 1.8e-22 79.3 11.5 3.1 1 1 1 2 2 2 2 Fungal domain of unknown function (DUF1712) SMN PF06003.7 XP_011275949.1 - 0.088 11.9 2.4 0.11 11.5 1.6 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Activator_LAG-3 PF11498.3 XP_011275949.1 - 0.22 10.2 22.2 0.25 10.0 15.4 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Vma12 PF11712.3 XP_011275949.1 - 0.36 10.5 4.8 0.51 10.0 3.3 1.3 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Neur_chan_memb PF02932.11 XP_011275949.1 - 0.46 10.3 5.7 0.54 10.0 4.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region APC_CDC26 PF10471.4 XP_011275949.1 - 0.48 11.1 17.3 0.68 10.7 3.4 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 Zip PF02535.17 XP_011275949.1 - 0.78 8.6 12.5 0.91 8.4 8.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Mannosyl_trans3 PF11051.3 XP_011275950.1 - 1.3e-83 280.5 0.0 2.4e-83 279.6 0.0 1.5 1 0 0 1 1 1 1 Mannosyltransferase putative NUMOD3 PF07460.6 XP_011275951.1 - 0.3 10.9 4.5 4.5 7.2 0.2 2.5 2 0 0 2 2 2 0 NUMOD3 motif (2 copies) DUF4538 PF15061.1 XP_011275952.1 - 0.028 13.7 0.0 0.098 11.9 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) DUF1741 PF08427.5 XP_011275952.1 - 7.6 5.9 10.6 0.56 9.6 3.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1741) AA_permease PF00324.16 XP_011275953.1 - 1.4e-107 359.9 36.8 1.8e-107 359.6 25.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 XP_011275953.1 - 2.9e-17 62.3 42.4 3.9e-17 61.9 29.4 1.1 1 0 0 1 1 1 1 Amino acid permease PIR PF00399.14 XP_011275954.1 - 2.8e-19 67.7 58.5 1.2e-05 24.4 4.9 5.3 5 0 0 5 5 5 4 Yeast PIR protein repeat DUF2404 PF10296.4 XP_011275955.1 - 3.7e-27 94.2 0.1 7.2e-27 93.3 0.1 1.5 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) PH_11 PF15413.1 XP_011275955.1 - 2.2e-08 34.3 0.0 2.2e-08 34.3 0.0 3.3 3 1 1 4 4 4 1 Pleckstrin homology domain PH PF00169.24 XP_011275955.1 - 5.6e-05 23.2 0.1 5.6e-05 23.2 0.0 2.4 3 0 0 3 3 3 1 PH domain PI3_PI4_kinase PF00454.22 XP_011275956.1 - 6.8e-55 186.0 0.4 1.8e-54 184.6 0.3 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase UME PF08064.8 XP_011275956.1 - 4.6e-30 103.7 6.4 6.1e-30 103.3 1.6 3.5 4 0 0 4 4 4 1 UME (NUC010) domain FAT PF02259.18 XP_011275956.1 - 1.2e-19 70.5 3.2 9.5e-19 67.5 0.9 2.9 2 1 0 2 2 2 1 FAT domain FATC PF02260.15 XP_011275956.1 - 2.2e-15 55.7 0.8 4.6e-15 54.7 0.6 1.6 1 0 0 1 1 1 1 FATC domain DUF3385 PF11865.3 XP_011275956.1 - 6.2e-06 26.2 3.9 4.5e-05 23.4 0.0 4.1 3 1 0 3 3 3 1 Domain of unknown function (DUF3385) TPR_11 PF13414.1 XP_011275956.1 - 0.043 13.4 8.6 1.5 8.4 0.2 4.3 4 0 0 4 4 4 0 TPR repeat CKS PF01111.14 XP_011275957.1 - 1.7e-16 59.8 0.0 2.2e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit PRMT5 PF05185.11 XP_011275958.1 - 7.7e-150 499.7 4.5 1e-149 499.3 3.1 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase AP_endonuc_2 PF01261.19 XP_011275958.1 - 7.8e-05 22.0 0.0 0.00014 21.2 0.0 1.4 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel HLH PF00010.21 XP_011275959.1 - 1.8e-19 69.1 0.5 6.9e-19 67.2 0.1 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain bZIP_1 PF00170.16 XP_011275959.1 - 0.016 15.1 1.5 0.046 13.6 1.0 1.7 1 0 0 1 1 1 0 bZIP transcription factor HALZ PF02183.13 XP_011275959.1 - 0.046 13.4 1.1 0.09 12.5 0.8 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper DivIC PF04977.10 XP_011275959.1 - 0.12 11.9 0.3 0.12 11.9 0.2 2.6 2 0 0 2 2 2 0 Septum formation initiator His_Phos_2 PF00328.17 XP_011275960.1 - 7.9e-42 143.8 0.0 9.3e-42 143.5 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF1571 PF07608.6 XP_011275960.1 - 0.074 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1571) DUF1415 PF07209.7 XP_011275960.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1415) His_Phos_2 PF00328.17 XP_011275961.1 - 1.1e-45 156.5 0.0 1.3e-45 156.2 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) AAA_12 PF13087.1 XP_011275962.1 - 2e-60 203.6 0.8 3.1e-60 202.9 0.6 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 XP_011275962.1 - 2.9e-17 63.0 0.2 1.6e-16 60.5 0.0 2.0 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 XP_011275962.1 - 6.1e-05 22.6 0.0 0.022 14.2 0.0 2.2 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.1 XP_011275962.1 - 0.00019 21.5 0.0 0.00041 20.4 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.1 XP_011275962.1 - 0.062 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 XP_011275963.1 - 9.4e-17 61.3 1.0 1.2e-16 61.0 0.2 1.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 XP_011275963.1 - 8.2e-11 41.5 0.0 1.3e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 XP_011275963.1 - 6e-08 32.5 0.0 8.4e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.16 XP_011275963.1 - 0.00014 21.3 0.1 0.00025 20.4 0.1 1.4 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain ResIII PF04851.10 XP_011275963.1 - 0.00074 19.3 0.0 0.0015 18.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.11 XP_011275963.1 - 0.00077 18.7 0.0 0.0019 17.5 0.0 1.6 1 0 0 1 1 1 1 PhoH-like protein DUF258 PF03193.11 XP_011275963.1 - 0.0035 16.5 0.1 0.007 15.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA PF00004.24 XP_011275963.1 - 0.0066 16.6 0.0 0.015 15.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DEAD PF00270.24 XP_011275963.1 - 0.01 15.3 0.1 0.016 14.6 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_16 PF13191.1 XP_011275963.1 - 0.014 15.3 0.0 0.053 13.5 0.0 1.9 3 0 0 3 3 3 0 AAA ATPase domain AAA_22 PF13401.1 XP_011275963.1 - 0.015 15.4 0.0 0.039 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 XP_011275963.1 - 0.015 14.9 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Helicase_RecD PF05127.9 XP_011275963.1 - 0.026 14.1 0.0 0.056 13.0 0.0 1.6 1 0 0 1 1 1 0 Helicase T2SE PF00437.15 XP_011275963.1 - 0.029 13.2 0.2 0.047 12.5 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Arch_ATPase PF01637.13 XP_011275963.1 - 0.074 12.7 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase AAA_25 PF13481.1 XP_011275963.1 - 0.08 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 XP_011275963.1 - 0.094 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 NACHT domain COPIIcoated_ERV PF07970.7 XP_011275964.1 - 1.4e-75 253.7 0.0 1.7e-75 253.4 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 XP_011275964.1 - 2.3e-32 110.8 0.4 2.3e-32 110.8 0.3 1.7 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Nrap PF03813.9 XP_011275965.1 - 0 1163.2 10.1 0 1163.0 7.0 1.0 1 0 0 1 1 1 1 Nrap protein DUF2201_N PF13203.1 XP_011275965.1 - 1.5 7.9 4.1 2.6 7.1 2.9 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain CDC45 PF02724.9 XP_011275965.1 - 4.1 5.3 13.2 6.7 4.6 9.1 1.3 1 0 0 1 1 1 0 CDC45-like protein LETM1 PF07766.8 XP_011275966.1 - 8.9e-98 326.5 4.7 8.9e-98 326.5 3.2 1.4 2 0 0 2 2 2 1 LETM1-like protein SAP PF02037.22 XP_011275966.1 - 0.035 13.6 0.0 0.08 12.4 0.0 1.7 1 0 0 1 1 1 0 SAP domain CwfJ_C_1 PF04677.10 XP_011275967.1 - 5.5e-24 84.1 1.5 1.2e-23 83.0 1.0 1.6 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 XP_011275967.1 - 1.8e-16 60.4 0.0 6.7e-16 58.5 0.0 2.0 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 STOP PF05217.7 XP_011275968.1 - 0.28 10.8 7.9 0.1 12.2 3.8 1.5 1 1 0 1 1 1 0 STOP protein AIF-MLS PF14962.1 XP_011275968.1 - 3 7.4 8.9 2.9 7.5 5.8 1.3 1 1 0 1 1 1 0 Mitochondria Localisation Sequence CRT10 PF08728.5 XP_011275968.1 - 3.7 5.4 14.3 4.2 5.2 9.9 1.0 1 0 0 1 1 1 0 CRT10 Spore_coat_CotO PF14153.1 XP_011275968.1 - 7.8 5.8 22.4 6.5 6.1 14.5 1.5 1 1 0 1 1 1 0 Spore coat protein CotO Tim44 PF04280.10 XP_011275969.1 - 3.3e-32 111.5 0.3 1.1e-31 109.8 0.0 1.9 2 0 0 2 2 2 1 Tim44-like domain Nuc_N PF14448.1 XP_011275969.1 - 0.012 15.1 0.1 0.28 10.7 0.0 2.5 2 0 0 2 2 2 0 Nuclease N terminal ChaB PF06150.7 XP_011275969.1 - 0.029 14.1 0.1 0.071 12.9 0.0 1.6 1 0 0 1 1 1 0 ChaB Spore_III_AB PF09548.5 XP_011275969.1 - 0.11 12.2 0.7 0.26 11.0 0.4 1.8 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) DUF624 PF04854.9 XP_011275969.1 - 0.19 11.5 0.3 17 5.3 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function, DUF624 Nab6_mRNP_bdg PF10567.4 XP_011275970.1 - 0.014 14.3 0.7 0.018 14.0 0.5 1.1 1 0 0 1 1 1 0 RNA-recognition motif DUF221 PF02714.10 XP_011275971.1 - 0.13 11.0 1.2 0.17 10.6 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF221 DUF4515 PF14988.1 XP_011275972.1 - 0.028 14.0 1.7 0.052 13.2 1.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) RINGv PF12906.2 XP_011275973.1 - 5.8e-16 58.2 4.7 9.4e-16 57.5 3.3 1.3 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 XP_011275973.1 - 0.026 14.3 7.0 0.045 13.5 4.9 1.4 1 0 0 1 1 1 0 Ring finger domain Cwf_Cwc_15 PF04889.7 XP_011275973.1 - 0.84 9.2 16.0 0.11 12.2 7.8 1.8 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein FANCL_C PF11793.3 XP_011275973.1 - 1.3 9.0 3.5 0.62 10.0 0.7 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain APC_CDC26 PF10471.4 XP_011275974.1 - 8.5e-14 52.0 5.3 1.2e-13 51.6 3.6 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex APC subunit 1 FUSC-like PF12805.2 XP_011275974.1 - 0.6 8.9 3.0 0.8 8.5 2.1 1.1 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS CENP-R PF06729.7 XP_011275975.1 - 0.92 9.1 5.1 0.2 11.3 0.7 1.7 1 1 1 2 2 2 0 Kinetochore component, CENP-R Cyclin_N PF00134.18 XP_011275976.1 - 1.1e-36 125.2 0.8 2.5e-36 124.0 0.6 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cupin_8 PF13621.1 XP_011275977.1 - 9.7e-48 162.8 0.0 3.4e-45 154.5 0.0 2.2 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 XP_011275977.1 - 0.00029 20.1 0.0 0.00084 18.6 0.0 1.7 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.17 XP_011275977.1 - 0.0056 16.9 0.0 0.022 14.9 0.0 2.0 2 0 0 2 2 2 1 JmjC domain, hydroxylase Daxx PF03344.10 XP_011275977.1 - 0.89 7.9 11.5 1.5 7.1 8.0 1.4 1 0 0 1 1 1 0 Daxx Family ARD PF03079.9 XP_011275977.1 - 1.9 8.4 0.0 1.9 8.4 0.0 3.2 3 0 0 3 3 3 0 ARD/ARD' family Nop14 PF04147.7 XP_011275977.1 - 3 5.6 21.0 6 4.6 14.5 1.5 1 0 0 1 1 1 0 Nop14-like family GAGA_bind PF06217.7 XP_011275978.1 - 0.73 9.7 9.5 1.6 8.6 6.6 1.5 1 0 0 1 1 1 0 GAGA binding protein-like family DUF2146 PF10220.4 XP_011275978.1 - 9.7 4.0 13.0 15 3.3 9.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) ETF_QO PF05187.8 XP_011275979.1 - 2.9e-41 139.8 0.2 1.1e-40 138.0 0.0 1.9 2 0 0 2 2 2 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 XP_011275979.1 - 4.6e-11 42.2 0.0 4.5e-05 22.5 0.0 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 XP_011275979.1 - 1.6e-07 30.5 0.1 0.0083 15.0 0.1 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.1 XP_011275979.1 - 2.3e-06 27.8 0.0 1.5e-05 25.1 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 XP_011275979.1 - 3.8e-06 26.8 0.0 9.2e-06 25.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 XP_011275979.1 - 1.4e-05 25.3 1.2 0.44 10.9 0.0 3.7 4 0 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 XP_011275979.1 - 1.7e-05 24.0 0.6 0.00023 20.3 0.4 2.1 1 1 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 XP_011275979.1 - 4.7e-05 22.0 0.3 0.0053 15.2 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein Thi4 PF01946.12 XP_011275979.1 - 9.9e-05 21.5 0.0 0.006 15.7 0.0 2.4 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 XP_011275979.1 - 0.00011 22.1 0.0 0.0003 20.7 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 XP_011275979.1 - 0.00021 21.1 0.0 0.00083 19.1 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_oxidored PF12831.2 XP_011275979.1 - 0.00065 18.8 0.0 0.001 18.2 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 XP_011275979.1 - 0.00072 18.3 0.0 0.47 9.0 0.1 2.3 2 0 0 2 2 2 2 Tryptophan halogenase Fer4_7 PF12838.2 XP_011275979.1 - 0.013 15.8 0.6 0.033 14.5 0.4 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain Lycopene_cycl PF05834.7 XP_011275979.1 - 0.039 12.8 0.1 0.055 12.3 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein K_oxygenase PF13434.1 XP_011275979.1 - 0.19 10.6 0.0 0.5 9.2 0.0 1.7 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) RhoGEF PF00621.15 XP_011275980.1 - 1.5e-39 135.7 6.6 1.5e-39 135.7 4.6 2.2 2 0 0 2 2 2 1 RhoGEF domain CDC24 PF06395.6 XP_011275980.1 - 4e-35 119.7 0.5 4e-35 119.7 0.4 2.4 3 0 0 3 3 3 1 CDC24 Calponin PH_10 PF15411.1 XP_011275980.1 - 3.9e-24 85.0 3.2 1.4e-23 83.2 2.2 2.1 1 0 0 1 1 1 1 Pleckstrin homology domain PB1 PF00564.19 XP_011275980.1 - 2.5e-11 43.0 0.2 6.4e-11 41.7 0.1 1.8 1 0 0 1 1 1 1 PB1 domain RNA_pol_A_bac PF01000.21 XP_011275981.1 - 3.6e-31 107.6 0.0 6e-31 106.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 XP_011275981.1 - 2e-13 49.2 0.0 2.7e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Hormone_4 PF00220.12 XP_011275981.1 - 0.1 12.3 1.0 0.33 10.7 0.7 1.9 1 0 0 1 1 1 0 Neurohypophysial hormones, N-terminal Domain Sugar_tr PF00083.19 XP_011275982.1 - 1e-82 278.1 29.1 1.3e-82 277.8 20.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 XP_011275982.1 - 3.3e-13 49.0 32.7 3.3e-13 49.0 22.7 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Ank_2 PF12796.2 XP_011275983.1 - 3.5e-24 84.9 4.6 2e-15 56.8 0.7 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 XP_011275983.1 - 2.1e-21 75.8 2.0 2.7e-08 34.1 0.1 3.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.25 XP_011275983.1 - 1.3e-20 72.0 8.4 5e-06 26.0 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 XP_011275983.1 - 7e-16 57.8 0.9 2.6e-07 30.6 0.1 4.0 2 2 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 XP_011275983.1 - 4e-14 51.3 7.3 0.024 14.8 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat Thr_dehydrat_C PF00585.13 XP_011275983.1 - 0.027 14.0 0.7 0.076 12.6 0.3 1.9 2 0 0 2 2 2 0 C-terminal regulatory domain of Threonine dehydratase Abhydrolase_6 PF12697.2 XP_011275984.1 - 1.3e-27 97.2 0.0 1.7e-27 96.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 XP_011275984.1 - 3.9e-18 65.8 0.0 5.3e-14 52.3 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 XP_011275984.1 - 5.2e-13 48.9 0.0 1.3e-09 37.9 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Ndr PF03096.9 XP_011275984.1 - 0.00015 20.3 0.0 0.0012 17.3 0.0 2.1 2 0 0 2 2 2 1 Ndr family BAAT_C PF08840.6 XP_011275984.1 - 0.00031 20.5 0.0 0.58 9.8 0.0 2.2 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.15 XP_011275984.1 - 0.00039 19.9 0.0 0.0006 19.3 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.3 XP_011275984.1 - 0.00054 19.7 0.0 0.0012 18.6 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase DUF2305 PF10230.4 XP_011275984.1 - 0.0065 15.9 0.1 0.015 14.7 0.0 1.6 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_3 PF07859.8 XP_011275984.1 - 0.012 15.1 0.0 0.04 13.5 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF915 PF06028.6 XP_011275984.1 - 0.021 13.9 0.0 0.072 12.1 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Peptidase_S9 PF00326.16 XP_011275984.1 - 0.042 13.0 0.0 0.83 8.8 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Ser_hydrolase PF06821.8 XP_011275984.1 - 0.053 13.1 0.0 0.095 12.2 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase PGAP1 PF07819.8 XP_011275984.1 - 0.094 12.2 0.0 0.19 11.2 0.0 1.5 1 1 0 1 1 1 0 PGAP1-like protein Chlorophyllase2 PF12740.2 XP_011275984.1 - 0.11 11.4 0.0 0.26 10.1 0.0 1.6 2 0 0 2 2 2 0 Chlorophyllase enzyme Thioesterase PF00975.15 XP_011275984.1 - 0.12 12.5 0.0 0.28 11.3 0.0 1.7 2 1 0 2 2 1 0 Thioesterase domain Peptidase_S28 PF05577.7 XP_011275984.1 - 0.14 10.6 0.0 0.21 10.1 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 DUF3169 PF11368.3 XP_011275985.1 - 0.019 14.2 0.0 0.024 13.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Cnd2 PF05786.9 XP_011275986.1 - 4.3e-120 402.4 34.2 6.6e-120 401.8 23.7 1.3 1 0 0 1 1 1 1 Condensin complex subunit 2 Aconitase PF00330.15 XP_011275987.1 - 2.6e-187 622.9 0.1 3.3e-187 622.6 0.1 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 XP_011275987.1 - 5.5e-43 146.2 0.0 1.3e-42 144.9 0.0 1.7 1 0 0 1 1 1 1 Aconitase C-terminal domain Ric8 PF10165.4 XP_011275988.1 - 1.4e-06 27.4 9.1 0.003 16.4 0.2 2.4 2 1 0 2 2 2 2 Guanine nucleotide exchange factor synembryn 2Fe-2S_thioredx PF01257.14 XP_011275989.1 - 1.9e-47 160.4 0.1 2.4e-47 160.1 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Transp_cyt_pur PF02133.10 XP_011275990.1 - 8.3e-17 60.8 39.5 1.8e-16 59.7 23.7 2.2 2 0 0 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin Copper-fist PF00649.13 XP_011275991.1 - 5.3e-22 76.7 2.0 1.5e-21 75.3 1.4 1.8 1 0 0 1 1 1 1 Copper fist DNA binding domain COX7B PF05392.6 XP_011275991.1 - 0.00029 20.3 0.5 0.094 12.3 0.1 2.5 2 0 0 2 2 2 2 Cytochrome C oxidase chain VIIB Ecm29 PF13001.2 XP_011275992.1 - 3.6e-120 401.8 0.5 1.1e-119 400.2 0.2 2.0 2 0 0 2 2 2 1 Proteasome stabiliser HEAT PF02985.17 XP_011275992.1 - 3.2e-13 48.5 0.3 0.027 14.5 0.0 7.8 7 0 0 7 7 7 3 HEAT repeat Vac14_Fab1_bd PF12755.2 XP_011275992.1 - 1.5e-06 28.5 0.3 0.02 15.2 0.0 5.6 5 0 0 5 5 5 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 XP_011275992.1 - 0.00016 22.0 0.0 12 6.5 0.0 6.4 6 0 0 6 6 6 1 HEAT-like repeat DUF937 PF06078.6 XP_011275992.1 - 0.00083 19.5 0.0 0.0031 17.7 0.0 2.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF937) ubiquitin PF00240.18 XP_011275993.1 - 3.2e-169 548.6 31.3 1.6e-33 113.8 0.6 5.0 5 0 0 5 5 5 5 Ubiquitin family Rad60-SLD PF11976.3 XP_011275993.1 - 3.7e-97 318.0 28.4 6.2e-19 67.4 0.5 5.0 5 0 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 XP_011275993.1 - 1.7e-29 101.8 15.8 0.00021 21.4 0.1 6.9 5 5 0 5 5 5 5 Ubiquitin-like domain Telomere_Sde2 PF13019.1 XP_011275993.1 - 8.8e-27 93.7 3.3 0.0011 18.6 0.0 5.0 5 0 0 5 5 5 5 Telomere stability and silencing Rad60-SLD_2 PF13881.1 XP_011275993.1 - 6.4e-17 61.4 5.0 0.16 11.8 0.0 5.9 5 4 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 XP_011275993.1 - 1.2e-16 60.6 4.8 0.18 12.0 0.0 5.2 1 1 4 5 5 5 5 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 XP_011275993.1 - 2.1e-13 50.1 0.0 1.9 8.5 0.0 5.9 5 0 0 5 5 5 5 Protein of unknown function (DUF2870) Methyltrans_RNA PF04452.9 XP_011275993.1 - 6.7e-08 31.9 1.4 2.8 7.0 0.0 4.4 4 0 0 4 4 4 4 RNA methyltransferase TUG-UBL1 PF11470.3 XP_011275993.1 - 2e-07 30.8 9.3 6.4 6.7 0.0 5.2 5 0 0 5 5 5 5 GLUT4 regulating protein TUG FlgD_ig PF13860.1 XP_011275993.1 - 1.7e-05 24.4 8.5 19 5.0 0.0 5.3 5 0 0 5 5 5 0 FlgD Ig-like domain Big_3_3 PF13750.1 XP_011275993.1 - 0.00014 21.3 0.0 66 2.8 0.0 4.9 5 0 0 5 5 5 0 Bacterial Ig-like domain (group 3) Plexin_cytopl PF08337.7 XP_011275993.1 - 0.00023 19.6 18.5 3.2 5.9 0.2 6.8 6 4 0 6 6 6 4 Plexin cytoplasmic RasGAP domain ACT_4 PF13291.1 XP_011275993.1 - 0.00039 20.6 1.5 1.4e+02 2.9 0.0 5.1 5 0 0 5 5 5 0 ACT domain CTDII PF01556.13 XP_011275993.1 - 0.018 14.8 19.8 11 6.0 0.2 5.4 1 1 4 5 5 5 0 DnaJ C terminal domain Tash_PEST PF07708.6 XP_011275993.1 - 0.026 14.4 38.3 4.5 7.3 1.2 5.4 5 0 0 5 5 5 0 Tash protein PEST motif GABP-alpha PF11620.3 XP_011275993.1 - 0.04 13.9 11.3 63 3.6 0.1 5.0 5 0 0 5 5 5 0 GA-binding protein alpha chain FERM_N PF09379.5 XP_011275993.1 - 0.16 12.0 17.3 58 3.8 0.1 7.0 5 5 0 5 5 5 0 FERM N-terminal domain DUF3781 PF12636.2 XP_011275993.1 - 0.8 9.7 11.2 1.3e+02 2.5 0.1 5.0 5 0 0 5 5 5 0 Protein of unknown function (DUF3781) ENTH PF01417.15 XP_011275994.1 - 2.8e-40 137.0 2.5 4.5e-40 136.3 1.7 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 XP_011275994.1 - 3.6e-08 32.4 0.4 4.5e-08 32.1 0.3 1.2 1 0 0 1 1 1 1 ANTH domain DUF1831 PF08866.5 XP_011275994.1 - 0.00084 19.5 1.4 0.011 16.0 0.1 2.2 2 0 0 2 2 2 1 Putative amino acid metabolism Prp19 PF08606.6 XP_011275995.1 - 4.1e-32 109.7 1.6 8.2e-32 108.7 1.1 1.5 1 0 0 1 1 1 1 Prp19/Pso4-like WEMBL PF05701.6 XP_011275995.1 - 0.015 13.8 4.7 0.029 12.8 3.3 1.4 1 1 0 1 1 1 0 Weak chloroplast movement under blue light Bul1_N PF04425.7 XP_011275996.1 - 3.6e-104 348.7 8.0 3.6e-104 348.7 5.6 2.2 3 0 0 3 3 3 1 Bul1 N terminus Bul1_C PF04426.7 XP_011275996.1 - 2.5e-25 89.1 9.0 1.5e-14 53.8 1.0 3.1 1 1 1 2 2 2 2 Bul1 C terminus Lip_prot_lig_C PF10437.4 XP_011275996.1 - 0.036 13.7 0.3 0.093 12.4 0.2 1.7 1 0 0 1 1 1 0 Bacterial lipoate protein ligase C-terminus Bul1_N PF04425.7 XP_011275997.1 - 4.5e-103 345.1 3.6 4.5e-103 345.1 2.5 1.8 2 0 0 2 2 2 1 Bul1 N terminus Bul1_C PF04426.7 XP_011275997.1 - 1.6e-24 86.5 13.8 9.1e-14 51.2 0.5 4.0 2 1 1 3 3 3 2 Bul1 C terminus DUF3546 PF12066.3 XP_011275997.1 - 1 9.4 6.7 0.54 10.2 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3546) Anp1 PF03452.9 XP_011275998.1 - 1.2e-118 395.1 0.0 8.2e-118 392.4 0.0 2.2 2 0 0 2 2 2 1 Anp1 MFS_1 PF07690.11 XP_011276000.1 - 6.8e-24 84.2 22.8 6.8e-24 84.2 15.8 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.11 XP_011276001.1 - 8.1e-27 93.8 29.6 1.1e-26 93.3 15.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2156 PF09924.4 XP_011276002.1 - 0.0023 16.8 0.0 0.0033 16.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) Acetyltransf_1 PF00583.19 XP_011276003.1 - 0.017 15.1 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family AMP-binding PF00501.23 XP_011276005.1 - 4.6e-67 226.2 0.0 6e-67 225.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme SAPS PF04499.10 XP_011276006.1 - 1e-157 525.6 18.1 1e-157 525.6 12.5 2.7 3 0 0 3 3 3 1 SIT4 phosphatase-associated protein Myosin_head PF00063.16 XP_011276008.1 - 1.2e-256 853.1 12.5 1.2e-256 853.1 8.7 1.7 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.14 XP_011276008.1 - 1e-33 115.3 0.8 1e-33 115.3 0.5 2.6 2 0 0 2 2 2 1 DIL domain IQ PF00612.22 XP_011276008.1 - 1.2e-07 30.7 20.4 0.0012 18.2 0.0 6.2 7 0 0 7 7 7 3 IQ calmodulin-binding motif AAA_22 PF13401.1 XP_011276008.1 - 2.4e-05 24.5 0.1 0.00026 21.1 0.0 2.9 2 0 0 2 2 2 1 AAA domain Myosin_N PF02736.14 XP_011276008.1 - 0.0011 18.5 0.0 0.0028 17.2 0.0 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain ADIP PF11559.3 XP_011276008.1 - 0.0056 16.5 17.0 0.0056 16.5 11.8 4.2 2 1 2 4 4 4 1 Afadin- and alpha -actinin-Binding ABC_tran PF00005.22 XP_011276008.1 - 0.082 13.2 0.1 0.082 13.2 0.0 3.6 2 1 0 2 2 2 0 ABC transporter AAA_19 PF13245.1 XP_011276008.1 - 0.11 12.2 0.0 0.35 10.6 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain Cep57_CLD_2 PF14197.1 XP_011276008.1 - 0.87 9.5 24.6 0.86 9.5 0.0 4.0 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 PEP-utilisers_N PF05524.8 XP_011276008.1 - 7.3 6.4 8.9 5.9 6.7 4.4 2.3 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal AdoHcyase PF05221.12 XP_011276009.1 - 1.3e-139 463.7 0.0 1.8e-139 463.2 0.0 1.2 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 XP_011276009.1 - 9.9e-82 272.5 2.4 1.6e-81 271.9 1.7 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 XP_011276009.1 - 4.3e-08 32.5 0.1 8.3e-08 31.5 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 XP_011276009.1 - 0.00086 18.7 0.5 0.0016 17.8 0.4 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain ELFV_dehydrog PF00208.16 XP_011276009.1 - 0.017 14.7 0.1 0.034 13.7 0.1 1.6 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TMEM107 PF14995.1 XP_011276009.1 - 0.02 14.9 0.0 0.036 14.1 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein TrkA_N PF02254.13 XP_011276009.1 - 0.021 14.7 0.1 0.048 13.6 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain GCS PF03074.11 XP_011276010.1 - 8.6e-135 449.5 0.3 1.2e-134 449.0 0.2 1.2 1 0 0 1 1 1 1 Glutamate-cysteine ligase GCS2 PF04107.8 XP_011276010.1 - 0.027 13.6 0.0 0.046 12.8 0.0 1.3 1 0 0 1 1 1 0 Glutamate-cysteine ligase family 2(GCS2) DnaJ PF00226.26 XP_011276011.1 - 1.2e-07 31.3 0.6 2.5e-07 30.3 0.1 1.9 3 0 0 3 3 3 1 DnaJ domain RNA_pol_Rpb1_3 PF04983.13 XP_011276011.1 - 0.062 13.0 0.8 0.31 10.7 0.0 2.0 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 3 TSGP1 PF07771.6 XP_011276011.1 - 0.089 12.6 0.4 0.19 11.6 0.3 1.6 1 0 0 1 1 1 0 Tick salivary peptide group 1 Adaptin_binding PF10199.4 XP_011276012.1 - 1.5e-09 38.2 2.2 6.7e-05 23.1 0.1 2.6 2 1 1 3 3 3 2 Alpha and gamma adaptin binding protein p34 Xan_ur_permease PF00860.15 XP_011276013.1 - 1.4e-67 227.9 30.4 2.3e-67 227.1 21.1 1.3 1 0 0 1 1 1 1 Permease family NIF3 PF01784.13 XP_011276014.1 - 6.5e-66 222.3 0.1 7.9e-66 222.0 0.1 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Copper-fist PF00649.13 XP_011276015.1 - 0.015 14.5 1.6 0.015 14.5 1.1 1.9 2 0 0 2 2 2 0 Copper fist DNA binding domain DUF1768 PF08719.6 XP_011276017.1 - 0.00048 19.9 0.1 0.00073 19.3 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Copper-fist PF00649.13 XP_011276017.1 - 0.06 12.5 0.1 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 Copper fist DNA binding domain DUF2404 PF10296.4 XP_011276018.1 - 9.6e-06 25.6 0.0 5.1e-05 23.3 0.0 2.2 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) DUF2262 PF10020.4 XP_011276018.1 - 0.074 13.2 5.1 0.2 11.8 3.5 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2262) Presenilin PF01080.12 XP_011276018.1 - 6.1 5.5 9.3 0.72 8.6 3.3 1.6 2 0 0 2 2 2 0 Presenilin BolA PF01722.13 XP_011276019.1 - 1.6e-19 69.5 0.0 1.9e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein RTX_C PF08339.5 XP_011276019.1 - 0.025 14.2 0.0 0.025 14.2 0.0 1.1 1 0 0 1 1 1 0 RTX C-terminal domain MFS_1 PF07690.11 XP_011276020.1 - 4.2e-32 111.2 14.5 4.2e-32 111.2 10.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Herpes_V23 PF01802.12 XP_011276020.1 - 0.092 11.7 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus VP23 like capsid protein Copper-fist PF00649.13 XP_011276021.1 - 0.00013 21.1 1.7 0.00013 21.1 1.2 2.0 2 0 0 2 2 2 1 Copper fist DNA binding domain Copper-fist PF00649.13 XP_011276022.1 - 0.0061 15.7 1.6 0.012 14.7 1.1 1.5 1 0 0 1 1 1 1 Copper fist DNA binding domain Frag1 PF10277.4 XP_011276023.1 - 8.3e-55 185.5 20.3 1e-54 185.2 14.1 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family UPF0016 PF01169.14 XP_011276023.1 - 0.1 12.7 3.1 0.26 11.4 2.1 1.8 1 1 0 1 1 1 0 Uncharacterized protein family UPF0016 TPT PF03151.11 XP_011276023.1 - 0.26 10.9 8.6 0.044 13.4 2.2 2.1 2 0 0 2 2 2 0 Triose-phosphate Transporter family RRN3 PF05327.6 XP_011276024.1 - 0.79 7.7 6.7 0.92 7.5 4.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 NPR3 PF03666.8 XP_011276024.1 - 4.7 5.6 7.6 5 5.5 5.2 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Kdo PF06293.9 XP_011276026.1 - 0.0017 17.4 0.1 0.0035 16.4 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family LMSTEN PF07988.7 XP_011276026.1 - 0.056 12.7 1.0 0.76 9.1 0.2 2.4 2 0 0 2 2 2 0 LMSTEN motif DASH_Ask1 PF08655.5 XP_011276027.1 - 6.8e-24 83.4 0.8 1.7e-23 82.2 0.3 2.0 2 0 0 2 2 2 1 DASH complex subunit Ask1 FA_hydroxylase PF04116.8 XP_011276028.1 - 1.2e-11 44.9 19.0 1.2e-11 44.9 13.2 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily SpoU_methylase PF00588.14 XP_011276029.1 - 1.5e-27 96.2 0.0 2.5e-27 95.4 0.0 1.4 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.7 XP_011276029.1 - 4.6e-12 45.9 0.0 1.2e-11 44.5 0.0 1.8 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding IGPD PF00475.13 XP_011276030.1 - 9.9e-61 203.8 0.3 1.7e-60 203.0 0.2 1.4 2 0 0 2 2 2 1 Imidazoleglycerol-phosphate dehydratase Mit_ribos_Mrp51 PF11709.3 XP_011276031.1 - 2.1e-67 227.5 0.9 2.9e-67 227.1 0.6 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit Luteo_coat PF00894.13 XP_011276031.1 - 0.07 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Luteovirus coat protein CDC45 PF02724.9 XP_011276033.1 - 0.85 7.5 9.8 0.75 7.7 6.8 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF778 PF05608.7 XP_011276033.1 - 2.3 8.1 5.0 19 5.2 3.5 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF778) DUF676 PF05057.9 XP_011276034.1 - 1e-46 159.0 0.2 1.8e-46 158.1 0.2 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 XP_011276034.1 - 1.3e-07 31.4 0.3 2.7e-07 30.4 0.2 1.4 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.20 XP_011276034.1 - 0.004 16.7 0.0 0.012 15.2 0.0 1.8 2 0 0 2 2 2 1 Lipase (class 3) Abhydrolase_5 PF12695.2 XP_011276034.1 - 0.013 15.2 0.0 0.041 13.6 0.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 XP_011276034.1 - 0.039 13.8 0.0 0.13 12.1 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family UPF0227 PF05728.7 XP_011276034.1 - 0.069 12.8 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Lipase_2 PF01674.13 XP_011276034.1 - 0.089 12.0 1.0 0.22 10.8 0.7 1.7 1 1 0 1 1 1 0 Lipase (class 2) Kdo PF06293.9 XP_011276035.1 - 0.0068 15.4 0.0 0.018 14.1 0.0 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Transketolase_C PF02780.15 XP_011276036.1 - 8.6e-09 35.3 0.0 1.2e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Transketolase, C-terminal domain MtrH PF02007.13 XP_011276036.1 - 0.039 12.9 0.0 0.054 12.4 0.0 1.2 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase MtrH subunit CDC45 PF02724.9 XP_011276037.1 - 0.0034 15.4 6.0 0.0051 14.9 4.1 1.3 1 0 0 1 1 1 1 CDC45-like protein DUF605 PF04652.11 XP_011276037.1 - 0.017 14.5 8.0 0.026 13.9 5.5 1.4 1 0 0 1 1 1 0 Vta1 like Nop14 PF04147.7 XP_011276037.1 - 0.017 13.0 12.2 0.029 12.3 8.5 1.3 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.4 XP_011276037.1 - 0.036 12.8 14.1 0.078 11.6 9.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF1510 PF07423.6 XP_011276037.1 - 0.11 11.8 10.3 0.77 9.0 6.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Sporozoite_P67 PF05642.6 XP_011276037.1 - 2.9 5.6 13.0 4.1 5.1 9.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen ESCRT-II PF05871.7 XP_011276038.1 - 5.2e-45 152.7 5.4 1.1e-44 151.7 3.7 1.5 1 1 0 1 1 1 1 ESCRT-II complex subunit Telomerase_RBD PF12009.3 XP_011276038.1 - 0.0022 17.8 0.7 0.0032 17.3 0.5 1.4 1 1 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain NifT PF06988.6 XP_011276038.1 - 0.093 12.2 0.1 4 6.9 0.0 2.5 2 1 0 2 2 2 0 NifT/FixU protein CENP-H PF05837.7 XP_011276039.1 - 1.7e-08 34.6 9.6 1.7e-08 34.6 6.7 2.0 2 0 0 2 2 2 1 Centromere protein H (CENP-H) Mod_r PF07200.8 XP_011276039.1 - 0.67 9.8 14.4 0.032 14.1 6.0 1.7 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Plasmid_parti PF01672.11 XP_011276039.1 - 4.4 7.7 15.1 5.4 7.5 0.3 3.1 2 2 1 3 3 3 0 Putative plasmid partition protein Sod_Fe_C PF02777.13 XP_011276040.1 - 1.5e-17 63.3 0.2 6.5e-08 32.3 0.0 2.5 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Scramblase PF03803.10 XP_011276041.1 - 3e-68 229.1 0.0 3.6e-68 228.9 0.0 1.0 1 0 0 1 1 1 1 Scramblase AA_permease PF00324.16 XP_011276042.1 - 1.1e-90 304.3 42.2 1.3e-90 304.0 29.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 XP_011276042.1 - 2.6e-27 95.4 45.1 3.5e-27 95.0 31.3 1.1 1 0 0 1 1 1 1 Amino acid permease DUF605 PF04652.11 XP_011276044.1 - 0.0004 19.9 4.3 0.00047 19.6 3.0 1.1 1 0 0 1 1 1 1 Vta1 like DUF843 PF05814.6 XP_011276044.1 - 0.0038 16.9 1.6 0.0079 15.9 1.1 1.5 1 0 0 1 1 1 1 Baculovirus protein of unknown function (DUF843) Med3 PF11593.3 XP_011276044.1 - 0.48 9.6 8.3 0.61 9.2 5.8 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal RNase_HII PF01351.13 XP_011276045.1 - 1.1 8.7 4.5 1.9 8.1 3.1 1.4 1 0 0 1 1 1 0 Ribonuclease HII Peptidase_C12 PF01088.16 XP_011276046.1 - 8.3e-60 201.6 0.0 1e-59 201.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 DUF2095 PF09868.4 XP_011276046.1 - 0.013 15.2 0.3 0.044 13.5 0.1 1.8 1 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2095) Glyco_hydro_38 PF01074.17 XP_011276047.1 - 9.1e-85 284.2 0.5 1.5e-84 283.5 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 XP_011276047.1 - 2.7e-68 230.8 0.1 4.9e-68 230.0 0.1 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 XP_011276047.1 - 3.2e-26 91.3 0.0 2.1e-25 88.7 0.0 2.3 2 0 0 2 2 2 1 Alpha mannosidase, middle domain Kdo PF06293.9 XP_011276048.1 - 0.0078 15.3 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Laminin_II PF06009.7 XP_011276049.1 - 0.056 13.2 0.8 0.11 12.2 0.3 1.5 1 1 0 1 1 1 0 Laminin Domain II DASH_Dad4 PF08650.5 XP_011276049.1 - 0.069 13.0 2.4 0.076 12.9 0.3 2.0 1 1 1 2 2 2 0 DASH complex subunit Dad4 NPV_P10 PF05531.7 XP_011276049.1 - 0.19 12.0 0.8 0.34 11.2 0.6 1.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Prenyltrans PF00432.16 XP_011276050.1 - 2.6e-22 78.0 10.8 0.0007 19.0 0.0 7.0 7 1 0 7 7 7 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 XP_011276050.1 - 6.6e-13 49.0 0.0 1.3e-07 32.0 0.0 3.6 2 1 1 3 3 3 3 Prenyltransferase-like WASH-7_C PF14746.1 XP_011276050.1 - 0.021 14.3 0.1 0.18 11.3 0.1 2.0 2 0 0 2 2 2 0 WASH complex subunit 7, C-terminal Mito_carr PF00153.22 XP_011276051.1 - 3.1e-54 180.6 2.4 7e-19 67.3 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein ACPS PF01648.15 XP_011276052.1 - 4.3e-11 42.6 0.0 7.5e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Pex14_N PF04695.8 XP_011276053.1 - 2.6e-43 147.3 0.4 2.6e-43 147.3 0.3 4.3 2 1 0 2 2 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region IncA PF04156.9 XP_011276053.1 - 0.0021 17.6 9.3 0.0021 17.6 6.5 2.2 2 0 0 2 2 2 1 IncA protein Vps53_N PF04100.7 XP_011276053.1 - 0.025 13.3 14.9 0.056 12.2 10.3 1.6 1 1 0 1 1 1 0 Vps53-like, N-terminal UPF0242 PF06785.6 XP_011276053.1 - 0.027 13.1 6.8 0.037 12.7 4.7 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) DUF479 PF04336.7 XP_011276053.1 - 0.048 13.7 0.1 0.22 11.6 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function, DUF479 Baculo_PEP_C PF04513.7 XP_011276053.1 - 0.11 12.2 10.6 0.094 12.5 4.8 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CCDC-167 PF15188.1 XP_011276053.1 - 0.29 11.1 11.6 5.4 7.0 0.1 2.7 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 DUF1664 PF07889.7 XP_011276053.1 - 0.33 10.7 12.5 5.8 6.7 8.7 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Peptidase_M16 PF00675.15 XP_011276053.1 - 0.47 10.1 6.4 6.7 6.4 2.7 2.6 2 1 0 2 2 2 0 Insulinase (Peptidase family M16) Ribosomal_L39 PF00832.15 XP_011276053.1 - 0.61 9.5 2.1 3.6 7.1 0.0 2.8 2 0 0 2 2 2 0 Ribosomal L39 protein Atg14 PF10186.4 XP_011276053.1 - 0.92 8.3 19.7 0.12 11.3 10.4 1.8 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4164 PF13747.1 XP_011276053.1 - 3 8.0 15.1 1.8 8.7 1.9 3.6 2 1 2 4 4 4 0 Domain of unknown function (DUF4164) DUF3086 PF11285.3 XP_011276053.1 - 3.2 6.4 9.2 0.39 9.4 3.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3086) Syntaxin PF00804.20 XP_011276053.1 - 3.4 7.8 27.4 1.2 9.3 10.9 2.9 1 1 1 2 2 2 0 Syntaxin Lebercilin PF15619.1 XP_011276053.1 - 6.7 6.0 24.1 1 8.7 13.9 1.6 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease PIN_2 PF10130.4 XP_011276053.1 - 7.5 6.5 9.9 3 7.9 2.5 2.9 2 1 1 3 3 3 0 PIN domain DivIC PF04977.10 XP_011276053.1 - 9.9 5.7 19.0 1.3 8.5 2.6 3.4 1 1 2 3 3 3 0 Septum formation initiator Med5 PF08689.5 XP_011276055.1 - 2.4e-94 316.8 68.3 6.9e-94 315.3 47.3 1.6 1 1 0 1 1 1 1 Mediator complex subunit Med5 Death PF00531.17 XP_011276055.1 - 0.03 14.0 0.0 0.13 11.9 0.0 2.2 1 0 0 1 1 1 0 Death domain Med2 PF11214.3 XP_011276055.1 - 1.3 9.1 8.9 0.085 12.9 1.1 2.9 3 0 0 3 3 3 0 Mediator complex subunit 2 Kdo PF06293.9 XP_011276056.1 - 0.0037 16.3 0.0 0.0081 15.2 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 XP_011276060.1 - 0.00031 19.9 1.6 0.0037 16.4 0.4 2.3 2 0 0 2 2 2 1 Protein kinase domain Choline_kinase PF01633.15 XP_011276060.1 - 0.0012 18.4 1.9 0.0012 18.4 1.3 2.0 2 1 0 2 2 2 1 Choline/ethanolamine kinase Histone PF00125.19 XP_011276061.1 - 2.6e-15 56.2 0.2 3.2e-15 56.0 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 XP_011276061.1 - 2.4e-05 24.3 0.1 3.3e-05 23.9 0.1 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 XP_011276061.1 - 2.6e-05 24.0 0.1 3.6e-05 23.6 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 XP_011276061.1 - 3.5e-05 23.7 0.1 5.9e-05 23.0 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 XP_011276061.1 - 0.00041 19.7 0.0 0.00044 19.6 0.0 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 XP_011276061.1 - 0.0026 17.4 0.0 0.0032 17.1 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.8 XP_011276061.1 - 0.057 13.7 0.1 0.11 12.8 0.1 1.4 1 1 0 1 1 1 0 Transcription initiation factor TFIID subunit A TFIID-31kDa PF02291.10 XP_011276061.1 - 0.12 12.1 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Glyco_transf_15 PF01793.11 XP_011276062.1 - 1.6e-122 408.6 15.2 2e-81 273.5 6.3 2.1 2 0 0 2 2 2 2 Glycolipid 2-alpha-mannosyltransferase PUL PF08324.6 XP_011276062.1 - 0.016 14.0 3.8 0.1 11.3 0.6 2.2 2 0 0 2 2 2 0 PUL domain Sds3 PF08598.6 XP_011276063.1 - 2e-43 148.2 13.8 3e-43 147.7 9.5 1.3 1 0 0 1 1 1 1 Sds3-like Met_10 PF02475.11 XP_011276064.1 - 4.3e-11 42.7 0.0 8.1e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 XP_011276064.1 - 0.0088 16.0 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 XP_011276064.1 - 0.017 14.5 0.0 0.04 13.3 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical protein 95 MTS PF05175.9 XP_011276064.1 - 0.03 13.6 0.0 0.07 12.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain zf-C2H2 PF00096.21 XP_011276065.1 - 5.3e-13 48.4 14.0 1.8e-06 27.9 2.5 4.0 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 XP_011276065.1 - 6.6e-12 45.0 12.4 1.4e-07 31.4 0.3 4.1 3 1 0 3 3 3 3 Zinc-finger double domain zf-met PF12874.2 XP_011276065.1 - 3.6e-06 26.9 3.1 0.00062 19.8 0.4 3.3 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 XP_011276065.1 - 1.8e-05 24.6 28.3 0.00068 19.7 2.1 4.2 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 XP_011276065.1 - 0.0018 18.3 0.6 0.0018 18.3 0.4 4.4 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding Zn_ribbon_recom PF13408.1 XP_011276065.1 - 0.013 15.7 1.0 0.013 15.7 0.7 2.0 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-BED PF02892.10 XP_011276065.1 - 3.8 7.3 8.5 3.4 7.5 1.3 3.4 2 1 1 3 3 3 0 BED zinc finger Bac_surface_Ag PF01103.18 XP_011276066.1 - 3.5e-40 138.4 14.1 3.5e-40 138.4 9.8 1.9 2 0 0 2 2 2 1 Surface antigen TRAPPC-Trs85 PF12739.2 XP_011276066.1 - 0.078 11.6 0.5 0.62 8.6 0.0 2.1 2 0 0 2 2 2 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit DFP PF04127.10 XP_011276067.1 - 6.2e-16 58.5 0.0 1e-07 31.7 0.0 2.1 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein RRM_1 PF00076.17 XP_011276068.1 - 6e-54 179.5 2.4 9.4e-19 66.8 0.7 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 XP_011276068.1 - 1.4e-40 137.1 0.2 1.1e-15 57.3 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 XP_011276068.1 - 1.3e-28 98.6 1.1 3.5e-12 45.9 0.3 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 XP_011276068.1 - 5.6e-05 22.8 0.0 0.053 13.3 0.0 2.9 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 XP_011276068.1 - 0.0068 16.2 10.8 0.017 14.9 0.1 3.7 4 0 0 4 4 4 2 RNA binding motif BRAP2 PF07576.7 XP_011276068.1 - 0.049 13.2 1.1 0.11 12.1 0.8 1.5 1 0 0 1 1 1 0 BRCA1-associated protein 2 CENP-T PF15511.1 XP_011276068.1 - 4.1 6.5 15.2 7.3 5.7 10.5 1.4 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T UCH PF00443.24 XP_011276069.1 - 1.9e-49 168.2 6.0 3.3e-49 167.4 4.2 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 XP_011276069.1 - 9e-17 61.4 6.4 6.8e-16 58.5 4.5 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase YqfQ PF14181.1 XP_011276069.1 - 7.5 6.5 18.5 1.2 9.1 1.1 2.8 2 0 0 2 2 2 0 YqfQ-like protein DUF1253 PF06862.7 XP_011276070.1 - 3.8e-160 533.1 7.4 5.7e-160 532.5 5.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) Nop14 PF04147.7 XP_011276070.1 - 0.94 7.3 39.6 1.7 6.4 27.5 1.4 1 0 0 1 1 1 0 Nop14-like family Transket_pyr PF02779.19 XP_011276071.1 - 4e-64 215.3 0.0 6.6e-64 214.6 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 XP_011276071.1 - 4e-55 186.6 0.0 5.4e-55 186.2 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component DUF4572 PF15139.1 XP_011276071.1 - 0.025 14.4 0.0 0.05 13.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4572) adh_short PF00106.20 XP_011276072.1 - 1.1e-21 77.4 0.0 1.7e-21 76.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 XP_011276072.1 - 3.8e-13 49.7 0.0 5e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 XP_011276072.1 - 1.1e-05 24.9 0.0 5e-05 22.8 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 XP_011276072.1 - 4.3e-05 23.6 0.0 8.8e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 XP_011276072.1 - 0.00033 20.3 0.0 0.00086 19.0 0.0 1.6 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.5 XP_011276072.1 - 0.02 14.0 0.0 0.095 11.8 0.0 1.9 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) SUN PF03856.8 XP_011276073.1 - 7.8e-100 333.2 13.5 7.8e-100 333.2 9.4 1.8 2 0 0 2 2 2 1 Beta-glucosidase (SUN family) CDC27 PF09507.5 XP_011276073.1 - 0.024 13.8 12.8 0.033 13.4 8.9 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Gag_spuma PF03276.9 XP_011276073.1 - 0.2 9.9 5.0 0.29 9.4 3.5 1.1 1 0 0 1 1 1 0 Spumavirus gag protein Macoilin PF09726.4 XP_011276073.1 - 2 6.5 22.1 2.6 6.2 15.3 1.0 1 0 0 1 1 1 0 Transmembrane protein Ashwin PF15323.1 XP_011276073.1 - 2.5 8.0 13.8 3.7 7.4 9.6 1.2 1 0 0 1 1 1 0 Developmental protein DUF2217 PF10265.4 XP_011276073.1 - 7.2 5.2 10.8 9.3 4.8 7.5 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DUF2722 PF10846.3 XP_011276074.1 - 1.7e-14 53.6 53.1 1.7e-14 53.6 36.8 4.8 1 1 2 3 3 3 1 Protein of unknown function (DUF2722) Glyco_hydro_3 PF00933.16 XP_011276076.1 - 3.3e-80 269.2 0.0 4.9e-80 268.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 XP_011276076.1 - 3.2e-68 229.6 0.0 3.1e-67 226.4 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 XP_011276076.1 - 7.3e-22 77.0 0.8 1e-20 73.4 0.2 2.4 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.7 XP_011276076.1 - 8.3e-16 57.9 0.7 1.7e-15 56.9 0.5 1.5 1 0 0 1 1 1 1 PA14 domain Phage_tail_X PF05489.7 XP_011276076.1 - 0.088 12.3 0.3 0.23 10.9 0.1 1.8 2 0 0 2 2 2 0 Phage Tail Protein X DUF2846 PF11008.3 XP_011276076.1 - 0.098 12.4 0.8 19 5.0 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2846) adh_short PF00106.20 XP_011276077.1 - 2.7e-30 105.4 0.2 3.5e-30 105.1 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 XP_011276077.1 - 3.7e-28 98.9 2.4 4.5e-28 98.6 1.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 XP_011276077.1 - 1.9e-11 43.9 0.0 3.1e-11 43.2 0.0 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 XP_011276077.1 - 4.8e-05 22.8 0.6 9.2e-05 21.9 0.4 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 XP_011276077.1 - 0.00039 19.2 0.2 0.0005 18.8 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Eno-Rase_NADH_b PF12242.3 XP_011276077.1 - 0.002 17.8 0.1 0.0051 16.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Sec15 PF04091.7 XP_011276077.1 - 0.029 13.7 0.6 0.039 13.2 0.4 1.2 1 0 0 1 1 1 0 Exocyst complex subunit Sec15-like NAD_binding_10 PF13460.1 XP_011276077.1 - 0.12 12.4 0.4 0.22 11.4 0.2 1.7 1 1 0 1 1 1 0 NADH(P)-binding APG17 PF04108.7 XP_011276077.1 - 0.12 11.1 0.8 0.17 10.6 0.6 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 Zn_clus PF00172.13 XP_011276078.1 - 6e-11 42.0 9.6 9.9e-11 41.3 6.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain bZIP_1 PF00170.16 XP_011276078.1 - 0.078 12.9 0.2 0.28 11.1 0.2 1.9 1 0 0 1 1 1 0 bZIP transcription factor BRCT PF00533.21 XP_011276081.1 - 1.2e-24 86.2 13.6 1.1e-13 51.1 0.2 4.8 5 0 0 5 5 5 4 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 XP_011276081.1 - 1.5e-17 63.1 0.1 6.3e-09 35.5 0.0 4.5 4 0 0 4 4 4 3 twin BRCT domain Pox_polyA_pol_N PF12630.2 XP_011276081.1 - 0.36 10.9 0.0 0.36 10.9 0.0 3.3 4 0 0 4 4 4 0 Poxvirus poly(A) polymerase N-terminal domain Paf1 PF03985.8 XP_011276082.1 - 2.8e-96 322.9 13.4 3.1e-96 322.7 9.3 1.0 1 0 0 1 1 1 1 Paf1 zf-C2H2_2 PF12756.2 XP_011276083.1 - 1.3e-32 111.8 3.8 4.1e-32 110.2 2.6 1.8 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) ROS_MUCR PF05443.6 XP_011276083.1 - 0.003 17.3 2.3 0.003 17.3 1.6 1.9 2 1 0 2 2 2 1 ROS/MUCR transcriptional regulator protein zf-C2H2_4 PF13894.1 XP_011276083.1 - 0.048 14.0 1.9 0.048 14.0 1.3 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger SDA1 PF05285.7 XP_011276083.1 - 0.51 9.5 31.9 0.064 12.5 5.1 2.3 2 0 0 2 2 2 0 SDA1 Hid1 PF12722.2 XP_011276083.1 - 1.8 6.1 12.6 2.7 5.5 8.7 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Phosphodiest PF01663.17 XP_011276084.1 - 1.2e-15 57.7 1.2 2.4e-14 53.4 0.8 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 XP_011276084.1 - 3.3e-06 26.6 0.7 1.6e-05 24.4 0.1 2.0 1 1 1 2 2 2 1 Metalloenzyme superfamily Ribosomal_L37 PF08561.5 XP_011276085.1 - 3.8e-26 90.4 2.2 5.3e-26 90.0 1.5 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 FB_lectin PF07367.6 XP_011276085.1 - 0.03 13.9 0.0 0.033 13.8 0.0 1.1 1 0 0 1 1 1 0 Fungal fruit body lectin DUF1674 PF07896.7 XP_011276087.1 - 1.9e-16 59.9 2.7 3e-16 59.3 1.8 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) DNA_pol_A_exo1 PF01612.15 XP_011276088.1 - 8.6e-47 158.8 0.2 1.5e-46 158.0 0.1 1.4 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 XP_011276088.1 - 1.3e-18 67.0 1.5 1.3e-18 67.0 1.0 3.5 3 0 0 3 3 3 1 PMC2NT (NUC016) domain HRDC PF00570.18 XP_011276088.1 - 2.2e-14 52.9 0.0 4.5e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 HRDC domain Aminotran_1_2 PF00155.16 XP_011276089.1 - 2.3e-83 280.1 0.0 2.9e-83 279.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 XP_011276089.1 - 2.5e-06 26.8 0.0 4e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 XP_011276089.1 - 6.9e-06 24.5 0.0 1.6e-05 23.4 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 XP_011276089.1 - 3.4e-05 22.7 0.5 0.00034 19.4 0.3 2.1 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 XP_011276089.1 - 0.00015 20.9 0.0 0.00024 20.3 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase OTCace_N PF02729.16 XP_011276090.1 - 1.4e-42 144.7 0.5 3.4e-42 143.4 0.1 1.8 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 XP_011276090.1 - 5.2e-42 143.3 0.2 8.8e-42 142.6 0.1 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain PHTB1_C PF14728.1 XP_011276090.1 - 0.031 13.0 0.3 0.079 11.7 0.0 1.7 2 0 0 2 2 2 0 PTHB1 C-terminus RNA_lig_T4_1 PF09511.5 XP_011276091.1 - 2e-75 253.1 0.7 5.5e-75 251.6 0.1 1.9 2 0 0 2 2 2 1 RNA ligase tRNA_lig_kinase PF08303.6 XP_011276091.1 - 1.6e-63 213.5 1.8 3.2e-63 212.5 1.2 1.5 1 0 0 1 1 1 1 tRNA ligase kinase domain tRNA_lig_CPD PF08302.6 XP_011276091.1 - 5.1e-46 156.9 0.0 8.7e-46 156.2 0.0 1.3 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain PRK PF00485.13 XP_011276091.1 - 0.047 13.2 0.0 0.14 11.7 0.0 1.8 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 XP_011276091.1 - 0.068 13.9 0.2 0.41 11.4 0.0 2.5 2 1 1 3 3 3 0 AAA domain FAD-oxidase_C PF02913.14 XP_011276092.1 - 2.6e-55 187.4 0.0 3.7e-55 186.9 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 XP_011276092.1 - 4.6e-39 133.0 0.0 8.6e-39 132.1 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain DNase_II PF03265.10 XP_011276093.1 - 0.032 13.2 0.7 0.039 12.9 0.5 1.3 1 0 0 1 1 1 0 Deoxyribonuclease II FlaC_arch PF05377.6 XP_011276093.1 - 0.096 12.5 3.6 0.18 11.6 1.0 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF972 PF06156.8 XP_011276093.1 - 0.22 11.8 10.6 2.3 8.6 1.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Prefoldin_2 PF01920.15 XP_011276093.1 - 0.44 10.3 8.3 0.095 12.4 1.6 2.2 2 0 0 2 2 2 0 Prefoldin subunit WD40_alt PF14077.1 XP_011276093.1 - 1.2 8.8 5.2 2.2 7.9 1.2 2.8 1 1 1 2 2 2 0 Alternative WD40 repeat motif RNA_pol_Rpc34 PF05158.7 XP_011276094.1 - 5.8e-92 308.3 2.8 6.9e-92 308.1 2.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit YopJ PF03421.11 XP_011276094.1 - 0.046 13.5 0.1 0.097 12.5 0.0 1.5 1 0 0 1 1 1 0 YopJ Serine/Threonine acetyltransferase BetR PF08667.5 XP_011276094.1 - 0.078 12.9 0.2 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 BetR domain B-block_TFIIIC PF04182.7 XP_011276094.1 - 0.12 12.2 0.3 1.1 9.1 0.1 2.3 1 1 1 2 2 2 0 B-block binding subunit of TFIIIC Rrf2 PF02082.15 XP_011276094.1 - 0.13 12.3 0.2 0.43 10.7 0.0 2.0 2 0 0 2 2 2 0 Transcriptional regulator Sod_Fe_C PF02777.13 XP_011276095.1 - 1.5e-33 114.7 0.8 2.7e-33 113.9 0.6 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 XP_011276095.1 - 2e-32 111.2 2.5 2e-32 111.2 1.7 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Methyltransf_16 PF10294.4 XP_011276096.1 - 5.7e-22 77.9 3.0 5.6e-21 74.7 0.0 2.5 3 0 0 3 3 3 1 Putative methyltransferase PrmA PF06325.8 XP_011276096.1 - 0.00042 19.5 0.1 0.0019 17.3 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.1 XP_011276096.1 - 0.0012 18.6 0.1 0.0032 17.2 0.0 1.8 3 0 0 3 3 3 1 Methyltransferase domain MTS PF05175.9 XP_011276096.1 - 0.022 14.1 0.0 0.039 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Cons_hypoth95 PF03602.10 XP_011276096.1 - 0.033 13.6 0.0 0.096 12.0 0.0 1.8 2 0 0 2 2 2 0 Conserved hypothetical protein 95 Minor_capsid_1 PF10665.4 XP_011276096.1 - 0.042 13.7 0.6 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 Minor capsid protein F-box-like PF12937.2 XP_011276096.1 - 0.12 12.0 0.3 0.37 10.5 0.2 1.9 1 1 0 1 1 1 0 F-box-like SRP1_TIP1 PF00660.12 XP_011276097.1 - 2.8e-20 72.0 0.9 5.4e-20 71.1 0.6 1.4 1 0 0 1 1 1 1 Seripauperin and TIP1 family DUF261 PF03196.8 XP_011276097.1 - 0.049 13.6 1.5 0.065 13.2 0.9 1.4 1 1 0 1 1 1 0 Protein of unknown function, DUF261 Calcyon PF06387.6 XP_011276097.1 - 0.097 12.0 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 D1 dopamine receptor-interacting protein (calcyon) ANTH PF07651.11 XP_011276098.1 - 0.028 13.1 1.3 0.058 12.0 0.9 1.5 2 0 0 2 2 2 0 ANTH domain Colicin_im PF03857.8 XP_011276098.1 - 0.077 12.7 0.1 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Colicin immunity protein ORC3_N PF07034.6 XP_011276099.1 - 4.6e-22 78.4 3.9 6.7e-22 77.8 2.7 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus Use1 PF09753.4 XP_011276100.1 - 1.4e-05 24.6 10.4 2.6e-05 23.8 7.2 1.4 1 1 0 1 1 1 1 Membrane fusion protein Use1 DUF912 PF06024.7 XP_011276100.1 - 0.046 13.7 12.1 0.062 13.3 0.4 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Phage_Nu1 PF07471.7 XP_011276100.1 - 0.072 12.5 2.1 0.12 11.7 1.3 1.5 1 1 1 2 2 2 0 Phage DNA packaging protein Nu1 XhlA PF10779.4 XP_011276100.1 - 1.7 8.6 11.8 3.7 7.5 3.7 2.6 2 0 0 2 2 2 0 Haemolysin XhlA U-box PF04564.10 XP_011276101.1 - 2.9e-24 84.8 0.3 6.7e-24 83.6 0.2 1.7 1 0 0 1 1 1 1 U-box domain TPR_11 PF13414.1 XP_011276101.1 - 1.4e-06 27.8 1.3 3.2e-06 26.7 0.7 1.9 1 1 0 1 1 1 1 TPR repeat TPR_1 PF00515.23 XP_011276101.1 - 9.1e-05 21.8 0.7 0.0015 18.0 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 XP_011276101.1 - 0.00018 21.1 0.6 0.0027 17.4 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 XP_011276101.1 - 0.00018 21.4 0.3 0.0011 19.0 0.0 2.5 3 0 0 3 3 1 1 Tetratricopeptide repeat TPR_19 PF14559.1 XP_011276101.1 - 0.00033 20.9 1.7 0.003 17.8 0.8 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 XP_011276101.1 - 0.00066 19.5 0.8 0.074 12.9 0.0 2.4 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 XP_011276101.1 - 0.025 14.3 0.2 0.14 12.0 0.1 2.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.1 XP_011276101.1 - 0.025 15.2 0.1 0.054 14.1 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF1657 PF07870.6 XP_011276101.1 - 0.044 13.4 2.5 0.21 11.2 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1657) zf-Nse PF11789.3 XP_011276101.1 - 0.054 13.0 0.0 0.33 10.4 0.0 2.3 1 1 1 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit SusD-like_3 PF14322.1 XP_011276101.1 - 0.11 12.6 0.2 0.11 12.6 0.1 2.6 1 1 1 3 3 3 0 Starch-binding associating with outer membrane AATF-Che1 PF13339.1 XP_011276101.1 - 3.3 7.8 12.6 0.57 10.3 2.0 2.4 2 1 1 3 3 3 0 Apoptosis antagonizing transcription factor Exo70 PF03081.10 XP_011276102.1 - 1.7e-74 250.8 17.4 1.7e-74 250.8 12.1 1.9 2 0 0 2 2 2 1 Exo70 exocyst complex subunit Reo_sigmaC PF04582.7 XP_011276102.1 - 4.4 6.3 17.7 1.7 7.7 5.0 2.2 2 0 0 2 2 2 0 Reovirus sigma C capsid protein APH PF01636.18 XP_011276103.1 - 0.014 15.1 0.0 0.029 14.1 0.0 1.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family Glyco_hydro_15 PF00723.16 XP_011276103.1 - 0.11 10.9 0.0 0.16 10.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 15 Arrestin_C PF02752.17 XP_011276105.1 - 8.4e-20 71.2 0.9 6.2e-16 58.7 0.1 3.1 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 XP_011276105.1 - 6.9e-09 35.6 0.0 1.3e-06 28.3 0.0 2.9 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain ER_lumen_recept PF00810.13 XP_011276106.1 - 1.4e-56 191.0 12.7 2.3e-56 190.3 8.8 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor HlyIII PF03006.15 XP_011276106.1 - 0.36 10.2 15.0 1.1 8.6 10.3 1.7 1 1 0 1 1 1 0 Haemolysin-III related Thioredoxin PF00085.15 XP_011276107.1 - 9.7e-27 92.6 0.0 2.4e-17 62.5 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.1 XP_011276107.1 - 4.3e-07 30.1 0.7 0.00018 21.6 0.1 3.1 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 XP_011276107.1 - 7.7e-05 22.7 8.3 0.015 15.4 0.1 3.8 3 2 1 4 4 4 2 Thioredoxin-like AhpC-TSA PF00578.16 XP_011276107.1 - 0.00026 20.6 0.9 0.0043 16.7 0.0 2.4 2 1 0 2 2 2 1 AhpC/TSA family Thioredoxin_7 PF13899.1 XP_011276107.1 - 0.0012 18.8 0.0 0.045 13.7 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin-like DUF4252 PF14060.1 XP_011276107.1 - 0.42 10.1 7.1 0.95 9.0 1.1 2.9 2 2 0 2 2 2 0 Domain of unknown function (DUF4252) Sod_Cu PF00080.15 XP_011276108.1 - 3.7e-45 153.5 5.0 4.3e-45 153.3 3.5 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) CTP_synth_N PF06418.9 XP_011276109.1 - 1.9e-119 397.8 0.1 2.6e-119 397.4 0.1 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 XP_011276109.1 - 1.7e-55 187.4 0.0 2.6e-55 186.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 XP_011276109.1 - 3.4e-06 26.6 0.0 7.3e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 CbiA PF01656.18 XP_011276109.1 - 0.0016 17.9 0.0 0.014 14.8 0.0 2.2 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain CLTH PF10607.4 XP_011276110.1 - 1.3e-27 96.2 9.7 1.3e-27 96.2 6.7 2.1 3 0 0 3 3 3 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.23 XP_011276110.1 - 4e-21 75.3 0.8 8.4e-21 74.3 0.5 1.6 1 0 0 1 1 1 1 SPRY domain COX4 PF02936.9 XP_011276112.1 - 4.9e-16 58.7 0.0 9e-16 57.8 0.0 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF1206 PF06724.6 XP_011276112.1 - 0.04 13.6 0.1 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) DUF1104 PF06518.6 XP_011276112.1 - 0.043 13.9 1.7 0.52 10.4 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1104) ABC_tran PF00005.22 XP_011276113.1 - 5.7e-34 117.3 0.0 1.7e-33 115.8 0.0 1.9 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 XP_011276113.1 - 2.8e-31 108.9 18.0 3.6e-31 108.5 12.5 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 XP_011276113.1 - 5.7e-11 42.9 3.7 1.6e-05 25.0 0.1 4.0 3 1 0 3 3 3 2 AAA domain SMC_N PF02463.14 XP_011276113.1 - 5.7e-08 32.2 2.1 2.6e-05 23.5 0.1 2.4 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 XP_011276113.1 - 4.2e-05 24.3 0.0 0.00014 22.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 XP_011276113.1 - 0.00012 22.1 0.0 0.00031 20.7 0.0 1.7 2 0 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.1 XP_011276113.1 - 0.00034 20.7 0.1 0.0025 17.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 XP_011276113.1 - 0.00047 19.6 0.1 0.0012 18.2 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_14 PF13173.1 XP_011276113.1 - 0.0047 16.8 0.3 0.058 13.2 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 XP_011276113.1 - 0.0048 16.3 0.2 0.024 14.0 0.0 2.0 1 1 1 2 2 2 1 AAA-like domain PHB_depo_C PF06850.6 XP_011276113.1 - 0.0059 15.8 0.0 0.015 14.5 0.0 1.6 2 0 0 2 2 2 1 PHB de-polymerase C-terminus AAA_18 PF13238.1 XP_011276113.1 - 0.0095 16.2 0.0 0.046 14.0 0.0 2.3 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 XP_011276113.1 - 0.011 14.9 0.0 0.026 13.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA PF00004.24 XP_011276113.1 - 0.032 14.4 0.0 0.31 11.2 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 XP_011276113.1 - 0.04 13.6 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 XP_011276113.1 - 0.047 13.1 0.0 0.091 12.2 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_25 PF13481.1 XP_011276113.1 - 0.066 12.6 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 XP_011276113.1 - 0.073 12.9 0.0 0.19 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain EF-hand_10 PF14788.1 XP_011276114.1 - 0.083 12.5 0.0 0.25 11.0 0.0 1.8 2 0 0 2 2 2 0 EF hand NMT1 PF09084.6 XP_011276115.1 - 9.1e-77 257.4 0.0 1.1e-76 257.1 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.1 XP_011276115.1 - 1.2e-08 34.7 0.1 0.0041 16.5 0.0 2.8 2 1 1 3 3 3 2 NMT1-like family FliM PF02154.10 XP_011276115.1 - 0.056 13.1 0.0 0.12 12.0 0.0 1.4 1 1 0 1 1 1 0 Flagellar motor switch protein FliM MFS_1 PF07690.11 XP_011276117.1 - 2.2e-33 115.4 28.0 1.3e-31 109.6 19.4 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily CbtB PF09489.5 XP_011276117.1 - 0.0056 16.5 0.9 1.4 8.8 0.0 3.0 2 0 0 2 2 2 2 Probable cobalt transporter subunit (CbtB) Zn_clus PF00172.13 XP_011276118.1 - 4.5e-08 32.8 8.1 7.7e-08 32.1 5.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Period_C PF12114.3 XP_011276118.1 - 0.068 12.7 8.0 0.1 12.2 5.5 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region DUF3415 PF11895.3 XP_011276118.1 - 0.081 12.8 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3415) Zn_clus PF00172.13 XP_011276119.1 - 6.7e-06 25.9 7.0 1.4e-05 24.8 4.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AT_hook PF02178.14 XP_011276119.1 - 0.67 9.8 3.8 1.3 8.9 2.6 1.5 1 0 0 1 1 1 0 AT hook motif DUF3445 PF11927.3 XP_011276121.1 - 2.4e-72 243.3 0.0 2.9e-72 243.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) DUF962 PF06127.6 XP_011276122.1 - 4e-25 87.5 2.0 5.6e-25 87.0 1.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF962) HAP PF03866.8 XP_011276122.1 - 0.061 13.1 0.4 0.12 12.1 0.1 1.5 1 1 0 1 1 1 0 Hydrophobic abundant protein (HAP) QueT PF06177.6 XP_011276122.1 - 0.15 11.9 6.6 0.082 12.8 2.8 1.8 1 1 0 1 1 1 0 QueT transporter DUF1600 PF07667.6 XP_011276122.1 - 0.3 11.2 13.2 0.079 13.0 7.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1600) YqzM PF14141.1 XP_011276122.1 - 5.3 6.9 8.9 0.3 10.8 0.3 2.8 2 0 0 2 2 2 0 YqzM-like protein PWI PF01480.12 XP_011276123.1 - 0.0083 16.2 2.5 0.0083 16.2 1.7 3.2 3 1 0 3 3 3 1 PWI domain MT-A70 PF05063.9 XP_011276124.1 - 2.3e-49 167.2 0.2 3.9e-49 166.5 0.1 1.4 1 0 0 1 1 1 1 MT-A70 COX6A PF02046.10 XP_011276125.1 - 1.5e-40 137.7 7.5 2.3e-40 137.1 5.2 1.3 1 1 0 1 1 1 1 Cytochrome c oxidase subunit VIa WD40 PF00400.27 XP_011276126.1 - 1.3e-13 50.1 2.1 0.0029 17.4 0.0 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat Chorismate_bind PF00425.13 XP_011276127.1 - 2.8e-89 298.8 0.0 3.8e-89 298.4 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 XP_011276127.1 - 5.5e-27 94.4 0.4 5.2e-25 88.0 0.0 3.0 2 1 0 2 2 2 1 Anthranilate synthase component I, N terminal region POR PF01558.13 XP_011276127.1 - 0.082 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase PP2C PF00481.16 XP_011276128.1 - 2.7e-75 253.0 0.0 9.1e-74 248.0 0.0 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 XP_011276128.1 - 0.0027 17.1 0.0 0.0076 15.6 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C TatD_DNase PF01026.16 XP_011276129.1 - 3.8e-53 180.3 0.0 2.6e-52 177.5 0.0 1.9 1 1 0 1 1 1 1 TatD related DNase Cyclin_N PF00134.18 XP_011276130.1 - 1.1e-10 41.1 1.5 2.4e-10 40.0 1.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain TRAM_LAG1_CLN8 PF03798.11 XP_011276131.1 - 5.9e-33 114.0 21.0 5.9e-33 114.0 14.6 2.0 2 1 1 3 3 3 1 TLC domain TRAM1 PF08390.6 XP_011276131.1 - 4.3e-19 67.7 2.5 4.3e-19 67.7 1.7 2.6 3 0 0 3 3 3 1 TRAM1-like protein MtN3_slv PF03083.11 XP_011276131.1 - 1.9 8.3 16.6 0.63 9.9 2.7 3.3 3 1 1 4 4 4 0 Sugar efflux transporter for intercellular exchange Aa_trans PF01490.13 XP_011276132.1 - 3.4e-90 302.4 29.3 4.1e-90 302.2 20.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 XP_011276132.1 - 1.2e-05 24.2 19.0 1.2e-05 24.2 13.2 1.8 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family Fungal_trans PF04082.13 XP_011276133.1 - 2.6e-20 72.3 9.7 4.3e-20 71.6 6.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 XP_011276133.1 - 1.1e-05 25.2 7.2 1.8e-05 24.5 5.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Y_phosphatase2 PF03162.8 XP_011276134.1 - 3.2e-61 205.4 0.0 4.5e-61 205.0 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 XP_011276134.1 - 2.9e-08 34.1 0.0 6.3e-08 33.0 0.0 1.6 2 1 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.15 XP_011276134.1 - 0.00053 19.5 0.0 0.001 18.6 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 XP_011276134.1 - 0.0016 17.8 0.0 0.0021 17.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF2416 PF10315.4 XP_011276135.1 - 5.5e-36 123.0 1.1 7.2e-36 122.7 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2416) Sugar_tr PF00083.19 XP_011276136.1 - 5.9e-48 163.5 33.8 3.4e-47 161.0 23.4 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 XP_011276136.1 - 3.3e-21 75.3 50.9 4.5e-15 55.2 21.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Exo_endo_phos PF03372.18 XP_011276137.1 - 5.1e-09 36.4 0.2 6.4e-09 36.1 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 XP_011276137.1 - 1.2e-05 24.8 0.3 3.3e-05 23.4 0.2 1.8 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase FtsH_ext PF06480.10 XP_011276137.1 - 0.37 10.9 2.2 1.3 9.2 0.3 2.6 2 1 0 2 2 2 0 FtsH Extracellular SlyX PF04102.7 XP_011276139.1 - 0.0047 17.2 1.2 0.0047 17.2 0.9 2.8 3 0 0 3 3 3 1 SlyX HTH_25 PF13413.1 XP_011276139.1 - 0.024 14.2 0.1 1.1 8.9 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain FliJ PF02050.11 XP_011276139.1 - 0.064 13.3 11.5 0.035 14.1 2.9 2.3 1 1 1 2 2 2 0 Flagellar FliJ protein MscS_porin PF12795.2 XP_011276139.1 - 0.085 12.1 12.0 0.14 11.4 8.3 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain DUF755 PF05501.6 XP_011276139.1 - 0.26 11.3 20.7 0.34 10.9 13.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF755) Reo_sigmaC PF04582.7 XP_011276139.1 - 0.96 8.5 7.0 1.4 8.0 4.9 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Transposase_24 PF03004.9 XP_011276139.1 - 1.1 9.0 10.0 0.13 12.1 3.5 1.9 2 0 0 2 2 2 0 Plant transposase (Ptta/En/Spm family) DUF2935 PF11155.3 XP_011276139.1 - 3.4 7.7 9.6 0.59 10.2 3.5 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) Fib_alpha PF08702.5 XP_011276139.1 - 9 6.4 20.0 1.9 8.6 7.8 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF1771 PF08590.5 XP_011276140.1 - 3e-18 65.5 9.5 5.5e-18 64.7 6.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.16 XP_011276140.1 - 6.2e-15 55.1 0.2 1.2e-14 54.2 0.1 1.5 1 0 0 1 1 1 1 Smr domain TCP PF03634.8 XP_011276140.1 - 9.3 6.6 9.5 2.2 8.6 1.8 2.1 2 0 0 2 2 2 0 TCP family transcription factor Ribosomal_L30 PF00327.15 XP_011276141.1 - 5.5e-19 67.4 1.2 9.4e-19 66.7 0.9 1.4 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.7 XP_011276141.1 - 3e-17 62.4 16.1 5.9e-17 61.4 11.1 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Sugar_tr PF00083.19 XP_011276142.1 - 4.1e-41 141.0 18.5 5e-41 140.7 12.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 XP_011276142.1 - 8.3e-24 83.9 23.1 9.6e-19 67.2 11.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily AA_permease PF00324.16 XP_011276143.1 - 3e-54 184.1 16.7 3.6e-54 183.8 11.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 XP_011276143.1 - 1.2e-15 57.0 16.9 1.4e-15 56.7 11.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 XP_011276144.1 - 3.6e-97 325.6 42.3 4.9e-97 325.2 29.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 XP_011276144.1 - 4.8e-19 68.2 45.2 6e-19 67.8 31.3 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1772 PF08592.6 XP_011276144.1 - 0.012 15.3 0.8 0.012 15.3 0.5 4.2 5 0 0 5 5 5 0 Domain of unknown function (DUF1772) AA_permease PF00324.16 XP_011276145.1 - 2.6e-98 329.4 40.4 3.1e-98 329.1 28.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 XP_011276145.1 - 2.4e-19 69.2 44.2 2.9e-19 68.9 30.6 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1772 PF08592.6 XP_011276145.1 - 0.0022 17.7 0.5 0.0022 17.7 0.3 4.1 3 1 1 4 4 4 1 Domain of unknown function (DUF1772) Ehbp PF10622.4 XP_011276146.1 - 0.019 14.9 0.6 1.5 8.7 0.1 2.4 1 1 1 2 2 2 0 Energy-converting hydrogenase B subunit P (EhbP) HAMP PF00672.20 XP_011276148.1 - 1.1e-38 131.2 9.6 3.2e-09 36.8 0.0 5.7 5 0 0 5 5 5 5 HAMP domain HATPase_c PF02518.21 XP_011276148.1 - 7.4e-29 99.7 0.2 2.1e-28 98.2 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 XP_011276148.1 - 1.1e-23 83.4 0.1 7.3e-23 80.7 0.0 2.5 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 XP_011276148.1 - 2.7e-15 56.1 0.1 1.1e-14 54.1 0.1 2.2 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain EDR1 PF14381.1 XP_011276148.1 - 0.6 9.6 4.8 0.38 10.2 0.1 3.0 3 1 1 4 4 4 0 Ethylene-responsive protein kinase Le-CTR1 DUF2365 PF10157.4 XP_011276148.1 - 3.2 7.6 19.0 3.9 7.3 0.0 6.4 3 1 2 7 7 7 0 Uncharacterized conserved protein (DUF2365) Zn_clus PF00172.13 XP_011276149.1 - 2e-06 27.5 7.3 3.7e-06 26.7 5.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 XP_011276149.1 - 5.6 7.2 11.3 0.95 9.6 2.3 2.2 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region FAA_hydrolase PF01557.13 XP_011276150.1 - 1.3e-55 188.2 0.0 1.4e-55 188.0 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family KH_2 PF07650.12 XP_011276150.1 - 0.018 14.5 0.1 0.044 13.3 0.1 1.6 1 0 0 1 1 1 0 KH domain RecR PF02132.10 XP_011276151.1 - 0.036 13.5 0.2 0.036 13.5 0.1 2.6 3 0 0 3 3 3 0 RecR protein zf-C3HC4_3 PF13920.1 XP_011276151.1 - 0.068 12.8 8.6 0.25 11.0 1.0 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 XP_011276151.1 - 0.095 12.5 9.2 0.051 13.4 2.0 2.4 2 0 0 2 2 2 0 Ring finger domain zf-rbx1 PF12678.2 XP_011276151.1 - 0.44 10.6 5.5 1.1 9.3 0.6 2.4 2 0 0 2 2 2 0 RING-H2 zinc finger DZR PF12773.2 XP_011276151.1 - 0.46 10.3 8.6 0.63 9.9 0.3 2.4 2 0 0 2 2 2 0 Double zinc ribbon zinc-ribbons_6 PF07191.7 XP_011276151.1 - 1.4 8.7 6.1 9 6.1 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbons Zn-ribbon_8 PF09723.5 XP_011276151.1 - 2.4 8.1 9.4 33 4.5 0.0 4.2 3 1 1 4 4 4 0 Zinc ribbon domain DUF1272 PF06906.6 XP_011276151.1 - 3.9 7.3 7.0 3.1 7.7 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zf-C3HC4_2 PF13923.1 XP_011276151.1 - 5.7 7.0 10.8 4.2 7.4 1.7 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_5 PF13719.1 XP_011276151.1 - 6.4 6.4 8.9 30 4.2 0.3 3.7 3 0 0 3 3 3 0 zinc-ribbon domain PPR_3 PF13812.1 XP_011276152.1 - 0.0012 18.9 0.1 13 6.3 0.0 4.8 5 0 0 5 5 5 1 Pentatricopeptide repeat domain F-box-like PF12937.2 XP_011276153.1 - 4e-06 26.4 2.1 5.6e-06 25.9 0.3 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 XP_011276153.1 - 0.0021 17.6 0.8 0.0055 16.3 0.5 1.8 1 0 0 1 1 1 1 F-box domain Phos_pyr_kin PF08543.7 XP_011276154.1 - 7.7e-12 44.9 0.0 1.1e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 XP_011276154.1 - 5e-07 29.1 0.0 2.7e-06 26.7 0.0 1.9 2 0 0 2 2 2 1 pfkB family carbohydrate kinase Med2 PF11214.3 XP_011276154.1 - 0.0015 18.5 0.1 0.0035 17.3 0.1 1.6 1 0 0 1 1 1 1 Mediator complex subunit 2 WD40 PF00400.27 XP_011276155.1 - 5.1e-09 35.6 0.3 5.4e-05 22.9 0.0 3.8 3 0 0 3 3 3 2 WD domain, G-beta repeat DPPIV_N PF00930.16 XP_011276155.1 - 0.00048 18.8 0.1 0.0019 16.8 0.0 1.9 2 0 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region PD40 PF07676.7 XP_011276155.1 - 0.0013 18.3 0.1 3.3 7.4 0.0 3.4 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat eIF2A PF08662.6 XP_011276155.1 - 0.05 13.3 0.1 1.1 8.8 0.0 2.4 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A zf-C3HC4_2 PF13923.1 XP_011276156.1 - 4.6e-09 36.1 18.7 1.8e-08 34.2 9.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 XP_011276156.1 - 1.8e-08 33.9 13.3 1.8e-08 33.9 9.2 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 XP_011276156.1 - 9.1e-08 31.8 13.4 7.5e-07 28.9 6.2 3.1 2 1 1 3 3 3 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 XP_011276156.1 - 1.1e-07 31.3 14.5 6e-07 29.0 6.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SAP PF02037.22 XP_011276156.1 - 6.1e-07 28.7 0.1 7.1e-06 25.4 0.0 2.5 2 0 0 2 2 2 1 SAP domain zf-RING_2 PF13639.1 XP_011276156.1 - 7.9e-07 28.8 16.5 5.1e-06 26.2 8.2 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.1 XP_011276156.1 - 1.4e-06 27.9 4.9 1.4e-06 27.9 3.4 3.7 3 1 1 4 4 4 1 RING-type zinc-finger zf-RING_5 PF14634.1 XP_011276156.1 - 3.6e-06 26.5 18.6 6e-06 25.8 8.2 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.1 XP_011276156.1 - 4.4e-05 23.1 5.4 4.4e-05 23.1 3.8 2.0 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 XP_011276156.1 - 0.0036 17.3 12.9 0.022 14.8 5.3 2.7 2 1 0 2 2 2 1 RING-H2 zinc finger U-box PF04564.10 XP_011276156.1 - 0.0053 16.7 0.1 0.029 14.3 0.0 2.2 2 0 0 2 2 2 1 U-box domain Baculo_IE-1 PF05290.6 XP_011276156.1 - 0.074 12.7 8.0 0.038 13.7 3.1 2.2 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) Rad50_zn_hook PF04423.9 XP_011276156.1 - 1.2 8.6 7.7 7 6.1 0.1 3.4 4 0 0 4 4 3 0 Rad50 zinc hook motif zf-Di19 PF05605.7 XP_011276156.1 - 1.8 8.7 9.5 0.75 9.9 0.2 2.9 3 0 0 3 3 2 0 Drought induced 19 protein (Di19), zinc-binding XPA_N PF01286.13 XP_011276156.1 - 2.8 7.6 6.0 19 5.0 0.2 3.1 3 0 0 3 3 3 0 XPA protein N-terminal zinc-ribbons_6 PF07191.7 XP_011276156.1 - 3.3 7.5 12.5 4.3 7.1 3.8 2.5 2 0 0 2 2 2 0 zinc-ribbons Prok-RING_4 PF14447.1 XP_011276156.1 - 4.2 6.9 11.2 15 5.1 0.0 2.9 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 XP_011276156.1 - 9.8 5.8 12.9 15 5.3 5.0 2.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Fork_head PF00250.13 XP_011276157.1 - 2.3e-33 114.0 0.3 5.7e-33 112.8 0.2 1.7 1 0 0 1 1 1 1 Fork head domain G10 PF01125.12 XP_011276158.1 - 9.1e-62 206.8 8.6 1e-61 206.7 6.0 1.0 1 0 0 1 1 1 1 G10 protein Phage_DsbA PF11126.3 XP_011276158.1 - 0.082 13.0 0.6 0.12 12.4 0.4 1.3 1 0 0 1 1 1 0 Transcriptional regulator DsbA zf-RING_5 PF14634.1 XP_011276158.1 - 5.6 6.7 13.4 12 5.6 3.0 2.3 1 1 1 2 2 2 0 zinc-RING finger domain Ytp1 PF10355.4 XP_011276159.1 - 7.3e-104 346.7 16.1 1.2e-103 346.0 11.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 XP_011276159.1 - 1.8e-34 117.4 7.7 1.8e-34 117.4 5.4 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) VIT1 PF01988.14 XP_011276159.1 - 0.46 9.9 11.6 0.076 12.4 0.8 3.3 3 0 0 3 3 3 0 VIT family MPC PF03650.8 XP_011276161.1 - 2e-38 131.0 0.0 2.3e-38 130.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) Pico_P1A PF02226.11 XP_011276161.1 - 0.079 12.7 0.0 0.65 9.7 0.0 2.2 2 0 0 2 2 2 0 Picornavirus coat protein (VP4) Adaptin_N PF01602.15 XP_011276163.1 - 2.4e-105 352.8 23.1 3.3e-105 352.4 16.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 XP_011276163.1 - 1.1e-07 31.8 2.0 1.1e-07 31.8 1.4 3.4 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 XP_011276163.1 - 0.00014 22.0 0.0 0.013 15.7 0.0 2.9 2 0 0 2 2 2 1 HEAT repeats HEAT PF02985.17 XP_011276163.1 - 0.0019 18.1 0.0 3.8 7.8 0.0 4.1 3 0 0 3 3 3 1 HEAT repeat HEAT_EZ PF13513.1 XP_011276163.1 - 0.0028 18.0 0.0 13 6.4 0.0 4.3 4 0 0 4 4 4 1 HEAT-like repeat Vac14_Fab1_bd PF12755.2 XP_011276163.1 - 0.015 15.6 0.7 6 7.3 0.1 3.4 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region RasGEF_N_2 PF14663.1 XP_011276163.1 - 0.017 15.0 0.8 1.2 9.0 0.0 3.4 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain KxDL PF10241.4 XP_011276164.1 - 2.4e-17 62.6 1.9 3.6e-17 62.0 1.3 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein HisKA_3 PF07730.8 XP_011276164.1 - 0.014 15.7 1.7 0.044 14.1 0.6 2.2 2 1 0 2 2 2 0 Histidine kinase Iron_permease PF04120.7 XP_011276164.1 - 0.037 13.6 0.3 0.066 12.8 0.2 1.5 1 0 0 1 1 1 0 Low affinity iron permease Vac_Fusion PF02346.11 XP_011276164.1 - 0.08 12.3 0.2 0.25 10.8 0.1 1.8 1 0 0 1 1 1 0 Chordopoxvirus fusion protein TLD PF07534.11 XP_011276165.1 - 3e-31 108.2 1.0 4.6e-31 107.6 0.7 1.3 1 0 0 1 1 1 1 TLD FA_desaturase PF00487.19 XP_011276166.1 - 4.9e-39 134.3 21.3 7.1e-39 133.7 14.8 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 XP_011276166.1 - 7e-09 35.3 0.0 1.5e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DEAD PF00270.24 XP_011276167.1 - 2.8e-50 170.0 0.0 7e-49 165.5 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 XP_011276167.1 - 6.8e-30 102.7 0.0 1e-28 99.0 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 XP_011276167.1 - 4.2e-08 33.2 9.0 2.9e-07 30.5 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 XP_011276167.1 - 0.0025 16.9 0.0 0.0025 16.9 0.0 3.4 2 1 1 3 3 3 1 U3-containing 90S pre-ribosomal complex subunit DUF1253 PF06862.7 XP_011276167.1 - 0.013 13.9 0.1 0.013 13.9 0.1 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF1253) AAA_11 PF13086.1 XP_011276167.1 - 1.6 8.2 14.4 3.1 7.3 7.0 2.8 2 1 0 2 2 2 0 AAA domain Pox_Ag35 PF03286.9 XP_011276167.1 - 3.6 7.0 31.2 5.8 6.3 20.9 1.9 2 0 0 2 2 2 0 Pox virus Ag35 surface protein SR-25 PF10500.4 XP_011276167.1 - 5.2 6.4 32.3 13 5.1 22.4 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Beta-lactamase PF00144.19 XP_011276168.1 - 7.7e-40 136.9 0.0 1.5e-39 135.9 0.0 1.3 1 1 0 1 1 1 1 Beta-lactamase Beta-lactamase PF00144.19 XP_011276169.1 - 5.9e-42 143.8 0.0 1.9e-41 142.1 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase Kri1_C PF12936.2 XP_011276171.1 - 1.5e-30 104.9 6.2 1.5e-30 104.9 4.3 5.4 5 1 1 6 6 6 1 KRI1-like family C-terminal Kri1 PF05178.7 XP_011276171.1 - 4.6e-19 68.5 21.5 4.6e-19 68.5 14.9 7.7 2 2 5 7 7 7 1 KRI1-like family CorA PF01544.13 XP_011276172.1 - 6.5e-43 146.8 0.2 1.1e-42 146.0 0.1 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF2231 PF09990.4 XP_011276172.1 - 0.11 12.8 0.0 0.21 11.9 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2231) CorA PF01544.13 XP_011276173.1 - 1.5e-44 152.1 3.4 5.7e-43 147.0 2.4 2.2 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein SUR7 PF06687.7 XP_011276173.1 - 0.012 15.1 0.1 0.021 14.3 0.1 1.3 1 0 0 1 1 1 0 SUR7/PalI family DUF2231 PF09990.4 XP_011276173.1 - 0.034 14.4 0.2 0.063 13.6 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2231) FAD-oxidase_C PF02913.14 XP_011276174.1 - 8.8e-48 162.7 0.0 1.1e-47 162.4 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 XP_011276174.1 - 4.6e-35 120.1 0.0 7.9e-35 119.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Ribosomal_S19e PF01090.14 XP_011276175.1 - 1.8e-51 173.2 0.0 2e-51 173.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e F-box-like PF12937.2 XP_011276176.1 - 0.011 15.4 0.1 0.038 13.7 0.1 2.0 1 0 0 1 1 1 0 F-box-like Ribosomal_L18e PF00828.14 XP_011276177.1 - 1.7e-21 76.9 0.1 2.8e-21 76.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Prefoldin PF02996.12 XP_011276178.1 - 1.7e-32 111.5 4.0 2.6e-32 110.9 2.8 1.3 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 XP_011276178.1 - 0.0079 15.9 6.3 0.05 13.3 0.2 2.3 1 1 0 2 2 2 2 Prefoldin subunit LOH1CR12 PF10158.4 XP_011276178.1 - 0.058 13.1 2.1 0.055 13.2 0.5 1.6 2 0 0 2 2 2 0 Tumour suppressor protein EHN PF06441.7 XP_011276178.1 - 0.095 12.6 0.5 0.36 10.7 0.0 2.0 2 0 0 2 2 2 0 Epoxide hydrolase N terminus CTP_transf_3 PF02348.14 XP_011276178.1 - 0.42 10.1 3.3 3.1 7.3 0.0 2.1 2 0 0 2 2 2 0 Cytidylyltransferase Aa_trans PF01490.13 XP_011276181.1 - 1.8e-25 89.2 31.7 2.9e-25 88.6 22.0 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein UPF0121 PF03661.8 XP_011276182.1 - 0.064 12.4 9.9 0.033 13.4 2.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0121) TPR_11 PF13414.1 XP_011276183.1 - 4.5e-11 42.2 2.9 7.5e-08 31.9 0.3 5.0 3 2 1 4 4 4 1 TPR repeat TPR_14 PF13428.1 XP_011276183.1 - 8.7e-07 29.0 0.1 1.1 10.1 0.0 6.0 3 2 4 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.12 XP_011276183.1 - 2.2e-06 27.1 0.4 0.89 9.6 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 XP_011276183.1 - 5.2e-06 25.8 0.7 0.23 11.3 0.0 5.1 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 XP_011276183.1 - 1.4e-05 24.4 1.6 9.1 6.3 0.0 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.23 XP_011276183.1 - 2.2e-05 23.8 1.0 0.12 11.9 0.0 5.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.1 XP_011276183.1 - 3e-05 23.8 0.3 0.066 13.4 0.0 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 XP_011276183.1 - 5.2e-05 23.3 0.7 0.024 14.7 0.4 4.0 2 2 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 XP_011276183.1 - 0.0024 17.7 0.9 1.1 9.2 0.1 4.4 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_15 PF13429.1 XP_011276183.1 - 0.0039 16.2 2.1 0.1 11.6 0.4 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 XP_011276183.1 - 0.0043 17.7 0.0 0.1 13.3 0.0 3.1 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 XP_011276183.1 - 0.0061 16.8 0.0 0.54 10.6 0.0 3.4 3 1 0 3 3 3 1 Tetratricopeptide repeat Sugar_tr PF00083.19 XP_011276184.1 - 3e-48 164.5 30.9 1.7e-47 162.0 21.4 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 XP_011276184.1 - 6.4e-22 77.7 50.9 1.2e-14 53.8 21.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-RING_2 PF13639.1 XP_011276185.1 - 3.9e-06 26.5 13.1 4.1e-06 26.5 7.8 2.0 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 XP_011276185.1 - 1.5e-05 24.9 6.8 3.9e-05 23.5 4.8 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 XP_011276185.1 - 0.001 18.7 7.9 0.0071 15.9 5.7 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 XP_011276185.1 - 0.015 15.0 8.9 0.015 15.0 6.2 1.8 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_UBOX PF13445.1 XP_011276185.1 - 0.029 14.0 4.2 0.061 13.0 1.6 2.6 2 1 1 3 3 3 0 RING-type zinc-finger Yip1 PF04893.12 XP_011276185.1 - 0.031 13.8 0.6 0.2 11.1 0.8 1.8 2 1 0 2 2 2 0 Yip1 domain TMEM190 PF15431.1 XP_011276185.1 - 0.035 14.0 0.0 0.099 12.5 0.0 1.9 1 0 0 1 1 1 0 Transmembrane protein 190 zf-DBF PF07535.7 XP_011276185.1 - 0.049 13.3 0.1 0.13 11.9 0.1 1.7 1 0 0 1 1 1 0 DBF zinc finger zf-rbx1 PF12678.2 XP_011276185.1 - 0.15 12.1 8.3 0.52 10.4 5.8 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger CRPA PF05745.6 XP_011276185.1 - 0.45 10.2 2.5 1.1 9.0 0.1 2.3 2 1 0 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) zf-RING_4 PF14570.1 XP_011276185.1 - 0.67 9.5 3.9 2.4 7.8 2.8 1.8 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.1 XP_011276186.1 - 2.1e-08 33.8 7.7 5e-08 32.6 5.3 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 XP_011276186.1 - 0.00041 20.0 9.0 0.00073 19.2 6.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 XP_011276186.1 - 0.012 15.2 7.5 0.04 13.5 5.2 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 XP_011276186.1 - 0.022 14.7 8.3 0.048 13.7 5.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 XP_011276186.1 - 0.14 12.2 8.9 0.62 10.2 6.1 2.2 1 1 0 1 1 1 0 RING-H2 zinc finger Epimerase PF01370.16 XP_011276187.1 - 1.3e-26 93.5 0.0 1.9e-26 92.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 XP_011276187.1 - 1.3e-19 69.9 0.4 2.2e-19 69.2 0.2 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 XP_011276187.1 - 5.1e-18 64.9 0.4 6e-10 38.4 0.1 2.1 1 1 1 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 XP_011276187.1 - 7.9e-15 55.3 0.0 1.4e-14 54.5 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 XP_011276187.1 - 3.4e-08 33.5 0.0 7.3e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 XP_011276187.1 - 1.3e-07 31.0 1.0 0.00017 20.9 0.1 2.2 2 0 0 2 2 2 2 NmrA-like family KR PF08659.5 XP_011276187.1 - 1.4e-06 28.1 0.0 2.8e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 XP_011276187.1 - 7.9e-06 24.9 0.4 1.5e-05 24.0 0.2 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 XP_011276187.1 - 5.2e-05 22.2 0.1 0.0019 17.1 0.0 2.6 3 0 0 3 3 3 1 RmlD substrate binding domain DapB_N PF01113.15 XP_011276187.1 - 0.037 13.9 0.1 0.1 12.4 0.1 1.8 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Shikimate_DH PF01488.15 XP_011276187.1 - 0.037 14.1 0.3 0.09 12.8 0.1 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase adh_short_C2 PF13561.1 XP_011276187.1 - 0.1 12.3 0.1 0.18 11.5 0.1 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Cation_efflux PF01545.16 XP_011276189.1 - 9.2e-40 136.4 12.8 1.2e-39 136.1 8.9 1.1 1 0 0 1 1 1 1 Cation efflux family CBM_21 PF03370.8 XP_011276190.1 - 2e-23 82.5 3.4 2e-23 82.5 2.4 2.4 2 0 0 2 2 2 1 Putative phosphatase regulatory subunit tRNA-synt_1c PF00749.16 XP_011276191.1 - 6.6e-109 363.3 0.0 2.6e-108 361.4 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.10 XP_011276191.1 - 3.2e-51 173.1 4.4 5.5e-51 172.3 3.1 1.4 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.13 XP_011276191.1 - 2.5e-33 115.1 1.6 8.5e-33 113.4 0.1 2.6 3 0 0 3 3 3 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.10 XP_011276191.1 - 8.5e-23 80.8 7.0 1.3e-22 80.2 3.8 2.1 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Red1 PF07964.6 XP_011276192.1 - 3.1e-25 88.4 74.2 3.3e-24 85.0 46.4 4.1 2 1 0 2 2 2 2 Rec10 / Red1 Ribosomal_L34e PF01199.13 XP_011276193.1 - 2e-37 127.3 5.7 2e-37 127.3 4.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L34e DUF1428 PF07237.6 XP_011276193.1 - 0.047 13.5 0.0 0.073 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1428) zf-3CxxC PF13695.1 XP_011276193.1 - 0.8 9.9 5.0 1.7 8.9 3.1 1.8 1 1 1 2 2 2 0 Zinc-binding domain PIN_4 PF13638.1 XP_011276194.1 - 3.7e-33 114.4 1.2 7.5e-33 113.4 0.8 1.5 1 0 0 1 1 1 1 PIN domain XLF PF09302.6 XP_011276195.1 - 8.1e-08 32.2 0.1 2.1e-07 30.9 0.1 1.7 1 0 0 1 1 1 1 XLF (XRCC4-like factor) TIM21 PF08294.6 XP_011276195.1 - 0.058 13.0 0.0 0.12 12.0 0.0 1.6 1 1 0 1 1 1 0 TIM21 DUF3910 PF13049.1 XP_011276195.1 - 0.11 12.5 1.0 0.3 11.2 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3910) RHD3 PF05879.7 XP_011276196.1 - 1.5e-212 707.6 17.6 3.5e-212 706.3 12.2 1.5 1 1 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) DUF410 PF04190.8 XP_011276197.1 - 2e-54 184.8 1.8 2.3e-54 184.6 1.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF410) NUDIX PF00293.23 XP_011276198.1 - 5.5e-16 58.4 0.2 6.7e-16 58.1 0.2 1.1 1 0 0 1 1 1 1 NUDIX domain WD40 PF00400.27 XP_011276199.1 - 2.6e-14 52.4 6.2 2.2e-08 33.6 1.5 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat BBS2_Mid PF14783.1 XP_011276199.1 - 0.017 14.9 0.8 23 4.8 0.0 3.7 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region F-box-like_2 PF13013.1 XP_011276200.1 - 0.041 13.6 0.7 0.13 11.9 0.1 2.2 1 1 1 2 2 2 0 F-box-like domain Aldolase_II PF00596.16 XP_011276201.1 - 1.8e-43 148.2 0.2 2.5e-43 147.8 0.2 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DUF3871 PF12987.2 XP_011276201.1 - 0.0018 17.0 0.0 0.0024 16.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function, B. Theta Gene description (DUF3871) Alg14 PF08660.6 XP_011276202.1 - 2.3e-51 174.1 0.1 3.1e-51 173.7 0.1 1.2 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like GPDPase_memb PF10110.4 XP_011276202.1 - 0.029 13.7 0.6 0.062 12.7 0.0 1.8 2 0 0 2 2 2 0 Membrane domain of glycerophosphoryl diester phosphodiesterase DcpS PF05652.7 XP_011276203.1 - 1.8e-35 121.6 0.3 4e-35 120.5 0.2 1.6 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.3 XP_011276203.1 - 4.2e-31 107.5 0.4 1.5e-30 105.7 0.0 2.2 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding Longin PF13774.1 XP_011276203.1 - 7.1e-25 86.3 0.4 1.7e-24 85.1 0.3 1.7 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 XP_011276203.1 - 1.1e-12 47.3 0.1 2.1e-12 46.4 0.1 1.4 1 0 0 1 1 1 1 Synaptobrevin DUF1664 PF07889.7 XP_011276203.1 - 0.0025 17.5 0.4 0.0025 17.5 0.3 2.0 3 0 0 3 3 3 1 Protein of unknown function (DUF1664) HIT PF01230.18 XP_011276203.1 - 0.033 14.6 0.3 0.19 12.2 0.0 2.4 2 0 0 2 2 2 0 HIT domain DUF4187 PF13821.1 XP_011276204.1 - 9.7e-15 53.9 2.6 3.2e-14 52.2 1.8 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.18 XP_011276204.1 - 2.3e-05 24.0 0.2 4.6e-05 23.1 0.2 1.5 1 0 0 1 1 1 1 G-patch domain CENP-R PF06729.7 XP_011276204.1 - 0.16 11.5 4.4 0.069 12.8 0.5 2.2 2 0 0 2 2 2 0 Kinetochore component, CENP-R UPF0004 PF00919.15 XP_011276205.1 - 0.13 12.1 0.3 0.16 11.8 0.2 1.3 1 1 0 1 1 1 0 Uncharacterized protein family UPF0004 Med4 PF10018.4 XP_011276206.1 - 4e-32 111.1 4.1 5.2e-32 110.7 1.7 1.8 1 1 1 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 MBOAT PF03062.14 XP_011276207.1 - 1.4e-59 201.8 8.3 1.4e-59 201.8 5.8 1.9 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Ferrochelatase PF00762.14 XP_011276208.1 - 5e-92 308.2 0.0 5.7e-92 308.0 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase Cnd1 PF12717.2 XP_011276209.1 - 8.6e-53 178.8 21.4 3.4e-50 170.3 0.7 4.7 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.2 XP_011276209.1 - 2.3e-45 154.2 2.0 2.3e-45 154.2 1.4 2.3 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT_2 PF13646.1 XP_011276209.1 - 3.1e-12 46.5 0.0 0.0028 17.9 0.0 4.9 3 1 1 4 4 4 3 HEAT repeats HEAT PF02985.17 XP_011276209.1 - 5.5e-11 41.5 4.8 0.022 14.7 0.0 6.6 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.1 XP_011276209.1 - 4e-06 27.1 0.1 11 6.6 0.0 5.6 4 2 2 6 6 6 3 HEAT-like repeat DUF2435 PF10363.4 XP_011276209.1 - 0.0069 16.2 0.3 11 6.0 0.0 4.2 2 1 1 3 3 3 2 Protein of unknown function (DUF2435) Cohesin_HEAT PF12765.2 XP_011276209.1 - 0.02 14.8 0.4 56 3.8 0.0 3.8 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion SUR7 PF06687.7 XP_011276210.1 - 3.2e-13 49.7 4.6 5.9e-13 48.8 3.2 1.4 1 1 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.3 XP_011276210.1 - 0.016 15.1 0.1 0.029 14.2 0.1 1.6 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 Snurportin1 PF11538.3 XP_011276210.1 - 0.075 12.8 0.2 0.13 12.0 0.2 1.3 1 0 0 1 1 1 0 Snurportin1 FUSC_2 PF13515.1 XP_011276210.1 - 0.52 10.2 7.2 0.16 11.8 2.9 1.6 2 0 0 2 2 2 0 Fusaric acid resistance protein-like SUR7 PF06687.7 XP_011276211.1 - 2.8e-06 27.0 9.8 5.4e-06 26.1 6.8 1.5 1 1 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.3 XP_011276211.1 - 0.2 11.5 6.9 0.04 13.8 1.7 2.0 2 1 1 3 3 3 0 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.7 XP_011276212.1 - 1.5e-16 60.6 4.7 1.9e-16 60.2 3.3 1.1 1 0 0 1 1 1 1 SUR7/PalI family Ninjurin PF04923.7 XP_011276212.1 - 1.1 9.0 0.0 1.1 9.0 0.0 2.5 3 1 0 3 3 3 0 Ninjurin TAF4 PF05236.9 XP_011276213.1 - 5.4e-54 183.2 5.8 1e-53 182.3 4.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family Histone PF00125.19 XP_011276213.1 - 0.035 14.2 0.1 0.079 13.0 0.0 1.6 1 1 0 1 1 1 0 Core histone H2A/H2B/H3/H4 RTC PF01137.16 XP_011276214.1 - 2e-53 180.5 0.0 2.3e-53 180.3 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 XP_011276214.1 - 1.8e-31 108.1 0.0 2.7e-31 107.6 0.0 1.2 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain PX PF00787.19 XP_011276215.1 - 5.3e-21 74.5 0.2 1.2e-20 73.3 0.1 1.7 1 0 0 1 1 1 1 PX domain MitMem_reg PF13012.1 XP_011276215.1 - 0.0039 17.2 0.1 1.1 9.4 0.0 2.8 2 1 0 2 2 2 2 Maintenance of mitochondrial structure and function DUF2404 PF10296.4 XP_011276216.1 - 0.00089 19.3 0.0 0.27 11.3 0.0 2.5 2 0 0 2 2 2 2 Putative integral membrane protein conserved region (DUF2404) DnaJ PF00226.26 XP_011276217.1 - 2.7e-15 55.8 1.4 2.7e-15 55.8 1.0 2.5 3 0 0 3 3 3 1 DnaJ domain DUF2462 PF09495.5 XP_011276217.1 - 2.7 8.7 5.3 16 6.3 1.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2462) SAP PF02037.22 XP_011276218.1 - 1.6e-09 37.0 1.4 2.8e-09 36.2 0.0 2.1 2 0 0 2 2 2 1 SAP domain Packaging_FI PF14000.1 XP_011276218.1 - 0.081 13.1 0.4 0.67 10.1 0.0 2.3 2 1 0 2 2 2 0 DNA packaging protein FI Adeno_E3 PF06040.6 XP_011276218.1 - 0.12 12.2 1.4 0.32 10.9 0.9 1.6 1 0 0 1 1 1 0 Adenovirus E3 protein DUF2076 PF09849.4 XP_011276219.1 - 3.8e-09 36.9 11.2 4.8e-09 36.6 7.8 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 XP_011276219.1 - 0.00032 20.5 2.8 0.00051 19.8 1.9 1.3 1 0 0 1 1 1 1 CHCH domain DUF605 PF04652.11 XP_011276219.1 - 0.017 14.5 8.2 0.018 14.4 5.7 1.1 1 0 0 1 1 1 0 Vta1 like CK1gamma_C PF12605.3 XP_011276219.1 - 0.065 13.8 13.8 2.3 8.8 6.0 2.1 2 0 0 2 2 2 0 Casein kinase 1 gamma C terminal HPP PF04982.8 XP_011276219.1 - 0.08 12.7 0.5 0.11 12.3 0.4 1.2 1 0 0 1 1 1 0 HPP family TFIIA PF03153.8 XP_011276219.1 - 3.8 7.3 8.8 4.5 7.0 6.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nucleoporin_FG PF13634.1 XP_011276219.1 - 4.4 7.5 20.7 8.2 6.7 14.4 1.5 1 1 0 1 1 1 0 Nucleoporin FG repeat region PAT1 PF09770.4 XP_011276219.1 - 7.7 4.6 16.6 8 4.5 11.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Transp_cyt_pur PF02133.10 XP_011276220.1 - 1e-98 330.8 28.7 1.2e-98 330.6 19.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Thioredoxin PF00085.15 XP_011276221.1 - 4.6e-16 58.3 0.2 5.4e-16 58.1 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 XP_011276221.1 - 4.5e-05 23.4 0.2 0.0011 19.0 0.1 2.3 1 1 1 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.16 XP_011276221.1 - 0.0017 18.0 0.2 0.003 17.2 0.1 1.4 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 XP_011276221.1 - 0.0061 16.1 0.2 0.067 12.7 0.1 2.0 1 1 1 2 2 2 1 Redoxin Thioredoxin_2 PF13098.1 XP_011276221.1 - 0.0064 16.6 0.3 0.24 11.6 0.2 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Phosducin PF02114.11 XP_011276221.1 - 0.019 13.7 0.0 0.024 13.3 0.0 1.1 1 0 0 1 1 1 0 Phosducin DUF2847 PF11009.3 XP_011276221.1 - 0.038 13.5 0.1 0.11 12.1 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2847) T4_deiodinase PF00837.12 XP_011276221.1 - 0.04 12.9 0.0 0.057 12.4 0.0 1.3 1 0 0 1 1 1 0 Iodothyronine deiodinase PQQ PF01011.16 XP_011276221.1 - 0.086 12.4 0.1 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 PQQ enzyme repeat Fungal_trans PF04082.13 XP_011276222.1 - 4.9e-15 55.1 1.0 1.7e-14 53.3 0.7 2.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 XP_011276222.1 - 1.8e-05 24.5 9.5 4.2e-05 23.3 6.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2346 PF09803.4 XP_011276222.1 - 0.24 11.2 2.1 1 9.2 1.4 2.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2346) DUF917 PF06032.7 XP_011276223.1 - 5.9e-97 324.3 0.0 8.5e-97 323.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 XP_011276223.1 - 1.2e-52 178.7 1.3 2.3e-50 171.3 0.2 2.3 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 XP_011276223.1 - 2.8e-29 101.8 0.1 2.3e-28 98.9 0.0 2.6 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region StbA PF06406.6 XP_011276223.1 - 0.011 14.7 0.0 5.6 5.8 0.0 2.8 2 0 0 2 2 2 0 StbA protein BcrAD_BadFG PF01869.15 XP_011276223.1 - 0.015 14.6 0.9 0.06 12.6 0.1 2.4 2 2 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family MutL PF13941.1 XP_011276223.1 - 0.024 12.9 0.8 1.6 6.9 0.1 2.6 3 0 0 3 3 3 0 MutL protein SRP54 PF00448.17 XP_011276223.1 - 0.09 12.2 0.8 0.26 10.6 0.0 2.0 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Complex1_49kDa PF00346.14 XP_011276224.1 - 9.3e-127 421.6 0.0 1.2e-126 421.2 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit Cytochrom_B_N PF00033.14 XP_011276225.1 - 0.048 13.0 0.0 0.071 12.4 0.0 1.2 1 0 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB FixQ PF05545.6 XP_011276225.1 - 0.071 12.7 0.3 0.14 11.8 0.2 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Surp PF01805.15 XP_011276225.1 - 0.092 12.4 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Surp module Topoisom_I_N PF02919.10 XP_011276226.1 - 2.2e-100 334.3 0.1 2.2e-100 334.3 0.1 3.0 3 1 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 XP_011276226.1 - 2.6e-80 268.9 0.2 2.6e-80 268.9 0.1 2.2 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 XP_011276226.1 - 7.8e-33 111.9 1.6 7.8e-33 111.9 1.1 2.5 2 0 0 2 2 2 1 C-terminal topoisomerase domain Herpes_LMP2 PF07415.6 XP_011276226.1 - 0.49 8.9 7.5 0.76 8.2 5.2 1.2 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Pkinase PF00069.20 XP_011276227.1 - 7.3e-71 238.3 0.0 1.3e-70 237.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011276227.1 - 1.3e-37 129.2 0.0 2e-37 128.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.13 XP_011276227.1 - 2.4e-30 104.2 0.1 2.2e-15 56.3 0.0 2.7 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.1 XP_011276227.1 - 2.2e-08 33.4 0.0 7.6e-08 31.6 0.0 1.7 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 XP_011276227.1 - 0.002 17.2 0.0 0.0035 16.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RNA_pol_L_2 PF13656.1 XP_011276228.1 - 1.2e-25 88.6 0.0 1.6e-25 88.3 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 XP_011276228.1 - 6.4e-11 41.2 0.0 9.5e-11 40.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNase_E_G PF10150.4 XP_011276228.1 - 0.028 13.6 0.0 0.032 13.4 0.0 1.1 1 0 0 1 1 1 0 Ribonuclease E/G family PAH PF02671.16 XP_011276229.1 - 4.1e-48 160.7 5.4 3.2e-18 65.0 0.2 4.4 4 0 0 4 4 4 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 XP_011276229.1 - 1.4e-43 146.7 0.2 1.4e-43 146.7 0.1 2.9 3 0 0 3 3 3 1 Sin3 family co-repressor zf-DHHC PF01529.15 XP_011276230.1 - 5.7e-17 61.6 1.9 8e-17 61.1 1.3 1.1 1 0 0 1 1 1 1 DHHC palmitoyltransferase DUF2410 PF10307.4 XP_011276231.1 - 1.1e-63 214.2 0.2 1.7e-63 213.6 0.1 1.3 1 0 0 1 1 1 1 Hypothetical protein (DUF2410) TetR_C_8 PF14278.1 XP_011276231.1 - 0.0088 16.4 0.4 0.032 14.6 0.3 2.0 1 0 0 1 1 1 1 Transcriptional regulator C-terminal region DAG_kinase_N PF14513.1 XP_011276231.1 - 0.071 13.3 0.1 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus WD40 PF00400.27 XP_011276232.1 - 1.1e-35 120.2 7.9 4.5e-09 35.8 0.0 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 XP_011276232.1 - 3.4e-07 30.1 0.1 0.068 12.8 0.0 4.4 4 1 1 5 5 5 3 Eukaryotic translation initiation factor eIF2A Sen15 PF09631.5 XP_011276232.1 - 0.025 14.8 1.4 5.4 7.3 0.0 3.7 3 0 0 3 3 3 0 Sen15 protein PD40 PF07676.7 XP_011276232.1 - 0.03 14.0 0.9 4.8 6.9 0.0 3.9 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat CUE PF02845.11 XP_011276233.1 - 7.2e-08 31.7 0.0 1.2e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 CUE domain DUF2232 PF09991.4 XP_011276233.1 - 0.0051 15.8 0.0 0.007 15.3 0.0 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2232) PH_4 PF15404.1 XP_011276233.1 - 0.094 12.2 1.7 0.38 10.2 0.5 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain DUF1183 PF06682.7 XP_011276233.1 - 0.12 11.9 1.5 5.7 6.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1183) DUF4636 PF15468.1 XP_011276233.1 - 0.17 11.2 3.6 0.38 10.1 1.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4636) FAM75 PF14650.1 XP_011276233.1 - 0.25 10.7 4.7 2.6 7.3 3.2 2.0 1 1 0 1 1 1 0 FAM75 family SAP30_Sin3_bdg PF13867.1 XP_011276234.1 - 7.4e-18 64.1 0.5 1.7e-14 53.4 0.1 2.4 2 0 0 2 2 2 2 Sin3 binding region of histone deacetylase complex subunit SAP30 DUF2874 PF11396.3 XP_011276234.1 - 0.11 12.5 0.5 0.21 11.5 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2874) CDK2AP PF09806.4 XP_011276234.1 - 3.9 7.6 8.6 6.6 6.9 5.9 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein LRR_4 PF12799.2 XP_011276235.1 - 8.2e-43 143.3 101.2 3e-07 29.8 0.2 13.3 7 3 7 14 14 14 12 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 XP_011276235.1 - 6e-40 134.8 82.7 6.7e-11 41.7 0.3 10.1 6 3 5 11 11 11 10 Leucine rich repeat PP2C PF00481.16 XP_011276235.1 - 4.5e-38 131.1 0.0 8.3e-38 130.2 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C Guanylate_cyc PF00211.15 XP_011276235.1 - 5.1e-24 84.6 0.0 1.1e-23 83.6 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 XP_011276235.1 - 2.2e-17 60.4 91.7 0.32 11.1 0.0 19.1 18 1 0 18 18 18 10 Leucine Rich Repeat LRR_7 PF13504.1 XP_011276235.1 - 1.2e-15 54.8 65.4 2.4 8.7 0.2 17.8 17 0 0 17 17 17 8 Leucine rich repeat LRR_6 PF13516.1 XP_011276235.1 - 0.00042 20.0 76.6 4.2 7.7 0.1 17.7 17 2 2 19 19 19 4 Leucine Rich repeat ArgJ PF01960.13 XP_011276236.1 - 1.6e-154 514.0 3.8 1.8e-154 513.8 2.7 1.0 1 0 0 1 1 1 1 ArgJ family Peptidase_M24 PF00557.19 XP_011276237.1 - 4.2e-30 104.8 0.0 5.5e-30 104.4 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 PHD PF00628.24 XP_011276238.1 - 2.3e-15 56.0 27.4 2.9e-09 36.4 10.3 3.2 2 1 1 3 3 3 2 PHD-finger Prok-RING_1 PF14446.1 XP_011276238.1 - 0.038 13.7 0.1 0.038 13.7 0.1 4.1 4 0 0 4 4 4 0 Prokaryotic RING finger family 1 C1_1 PF00130.17 XP_011276238.1 - 2 8.2 19.6 0.084 12.6 3.5 3.1 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H PF13771.1 XP_011276238.1 - 2.9 8.1 10.8 0.19 11.8 2.5 2.5 2 0 0 2 2 2 0 PHD-like zinc-binding domain PHD_2 PF13831.1 XP_011276238.1 - 8.5 5.7 13.9 7.3 6.0 0.2 3.6 3 0 0 3 3 3 0 PHD-finger HEAT PF02985.17 XP_011276239.1 - 5.9e-08 32.1 0.1 0.22 11.7 0.0 5.7 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.1 XP_011276239.1 - 7.6e-06 26.1 0.0 0.00062 19.9 0.0 3.2 2 0 0 2 2 2 1 HEAT repeats Arm PF00514.18 XP_011276239.1 - 0.0028 17.4 4.8 0.083 12.7 0.0 4.5 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Form_Nir_trans PF01226.12 XP_011276240.1 - 6.7e-65 218.4 14.9 8.1e-65 218.1 10.3 1.1 1 0 0 1 1 1 1 Formate/nitrite transporter Sec20 PF03908.8 XP_011276241.1 - 2.3e-14 52.8 1.3 6.1e-14 51.4 0.9 1.8 1 0 0 1 1 1 1 Sec20 Phage_B PF02304.10 XP_011276241.1 - 0.1 12.9 1.1 0.27 11.5 0.8 1.7 1 0 0 1 1 1 0 Scaffold protein B RNA_pol_Rpb1_5 PF04998.12 XP_011276242.1 - 0.69 9.1 10.7 0.087 12.0 3.8 1.9 1 1 1 2 2 2 0 RNA polymerase Rpb1, domain 5 Tim17 PF02466.14 XP_011276245.1 - 7.3e-29 100.4 2.5 9.4e-29 100.0 1.8 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Dus PF01207.12 XP_011276246.1 - 1.5e-45 155.4 0.0 1e-44 152.6 0.0 2.2 1 1 1 2 2 2 1 Dihydrouridine synthase (Dus) DUF2201_N PF13203.1 XP_011276246.1 - 0.016 14.3 4.2 0.045 12.9 2.3 2.0 2 0 0 2 2 2 0 Putative metallopeptidase domain DUF2422 PF10337.4 XP_011276246.1 - 0.059 12.1 4.3 0.085 11.6 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) TMP-TENI PF02581.12 XP_011276246.1 - 0.086 11.9 0.0 0.19 10.8 0.0 1.5 1 0 0 1 1 1 0 Thiamine monophosphate synthase/TENI U79_P34 PF03064.11 XP_011276246.1 - 0.68 9.3 18.6 0.99 8.8 12.9 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 GAGA_bind PF06217.7 XP_011276246.1 - 2.3 8.0 12.3 3.7 7.4 8.6 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Spore_coat_CotO PF14153.1 XP_011276246.1 - 3.3 7.1 22.4 5 6.5 15.5 1.2 1 0 0 1 1 1 0 Spore coat protein CotO DUF1708 PF08101.6 XP_011276247.1 - 2.5e-39 135.3 21.3 3.4e-39 134.8 13.3 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF1708) WD40 PF00400.27 XP_011276248.1 - 0.0035 17.1 0.0 0.87 9.5 0.0 4.0 5 0 0 5 5 5 1 WD domain, G-beta repeat IPP-2 PF04979.9 XP_011276249.1 - 1.6 8.9 6.0 0.82 9.9 1.3 2.1 1 1 1 2 2 2 0 Protein phosphatase inhibitor 2 (IPP-2) GFO_IDH_MocA PF01408.17 XP_011276250.1 - 6.3e-23 81.5 0.0 1.6e-22 80.3 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 XP_011276250.1 - 7.2e-07 29.0 0.0 1.2e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain MFS_1 PF07690.11 XP_011276251.1 - 2.4e-34 118.5 30.3 2.4e-34 118.5 21.0 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans_2 PF11951.3 XP_011276252.1 - 1.4e-90 303.7 3.8 2e-90 303.1 2.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 XP_011276252.1 - 1.1e-08 34.8 9.0 2.1e-08 33.9 6.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIID-18kDa PF02269.11 XP_011276253.1 - 3.3e-28 97.3 0.2 6.2e-28 96.4 0.1 1.5 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CENP-S PF15630.1 XP_011276253.1 - 3.3e-05 23.9 0.0 6.6e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Kinetochore component CENP-S Bromo_TP PF07524.8 XP_011276253.1 - 0.004 16.8 0.0 0.0074 16.0 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TAF PF02969.12 XP_011276253.1 - 0.02 14.8 0.1 0.15 12.0 0.0 2.2 2 0 0 2 2 2 0 TATA box binding protein associated factor (TAF) TFIID_20kDa PF03847.8 XP_011276253.1 - 0.071 13.3 0.1 0.18 12.1 0.1 1.7 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Histone PF00125.19 XP_011276253.1 - 0.13 12.4 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 RR_TM4-6 PF06459.7 XP_011276253.1 - 1.3 8.8 10.1 1.5 8.6 7.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ERO1 PF04137.10 XP_011276254.1 - 8.8e-93 311.1 7.6 1.3e-92 310.5 5.3 1.2 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) RVT_connect PF06815.8 XP_011276254.1 - 0.033 14.0 0.0 0.093 12.6 0.0 1.7 1 0 0 1 1 1 0 Reverse transcriptase connection domain NUFIP1 PF10453.4 XP_011276255.1 - 2.9e-06 26.7 10.1 2.9e-06 26.7 7.0 3.8 2 1 2 4 4 4 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) DUF1501 PF07394.7 XP_011276255.1 - 0.4 9.4 6.3 0.51 9.1 4.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Zip PF02535.17 XP_011276255.1 - 1.7 7.6 12.2 3.1 6.7 8.4 1.5 1 1 0 1 1 1 0 ZIP Zinc transporter Transformer PF06495.6 XP_011276255.1 - 3.5 7.4 13.4 11 5.8 9.5 1.6 1 1 1 2 2 2 0 Fruit fly transformer protein Glyco_hydro_17 PF00332.13 XP_011276257.1 - 4.5e-08 32.4 0.9 1.1e-07 31.1 0.1 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 17 Phyto_Pns9_10 PF05878.6 XP_011276257.1 - 0.054 12.5 4.1 0.037 13.0 0.8 2.0 2 0 0 2 2 2 0 Phytoreovirus nonstructural protein Pns9/Pns10 Macoilin PF09726.4 XP_011276257.1 - 0.43 8.8 15.6 0.47 8.6 10.8 1.2 1 0 0 1 1 1 0 Transmembrane protein SOG2 PF10428.4 XP_011276257.1 - 0.5 8.9 9.1 0.63 8.6 6.3 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Bromodomain PF00439.20 XP_011276258.1 - 6.2e-34 115.7 3.3 2.4e-16 59.4 0.2 2.4 2 0 0 2 2 2 2 Bromodomain BAH PF01426.13 XP_011276258.1 - 7.4e-22 77.3 0.1 1.7e-21 76.2 0.1 1.6 1 0 0 1 1 1 1 BAH domain SIR2 PF02146.12 XP_011276259.1 - 2.5e-38 131.5 0.0 3.2e-37 127.9 0.0 2.1 1 1 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.17 XP_011276259.1 - 0.14 11.8 0.0 0.95 9.2 0.0 2.0 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain HSP70 PF00012.15 XP_011276260.1 - 1.6e-236 785.9 12.8 1.8e-236 785.7 8.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 XP_011276260.1 - 1.3e-16 60.0 7.2 4.4e-15 55.1 0.5 2.5 3 0 0 3 3 3 2 MreB/Mbl protein FGGY_C PF02782.11 XP_011276260.1 - 7e-05 22.5 0.0 0.00014 21.5 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 XP_011276260.1 - 0.0031 17.3 9.1 1.5 8.7 1.2 4.8 3 1 0 3 3 3 2 Cell division protein FtsA Hydantoinase_A PF01968.13 XP_011276260.1 - 0.14 11.2 2.3 1.1 8.2 0.2 2.7 2 1 0 2 2 2 0 Hydantoinase/oxoprolinase DUF2681 PF10883.3 XP_011276261.1 - 0.0079 16.3 1.7 1.1 9.4 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2681) CO_dh PF02552.11 XP_011276261.1 - 0.11 12.0 0.5 2.6 7.5 0.0 2.2 1 1 1 2 2 2 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit DUF2031 PF09592.5 XP_011276261.1 - 4.2 6.4 7.8 0.31 10.1 0.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2031) RhoGAP PF00620.22 XP_011276262.1 - 2.9e-33 114.6 0.4 7.3e-33 113.3 0.2 1.7 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 XP_011276262.1 - 2.9e-26 91.3 55.2 2.3e-12 46.7 2.0 4.5 4 0 0 4 4 4 4 LIM domain DNA_pol_A_exo1 PF01612.15 XP_011276264.1 - 4e-05 23.1 0.0 0.0001 21.8 0.0 1.6 1 0 0 1 1 1 1 3'-5' exonuclease FliE PF02049.13 XP_011276265.1 - 0.015 15.3 4.5 0.016 15.1 3.1 1.1 1 0 0 1 1 1 0 Flagellar hook-basal body complex protein FliE Nrf1_activ_bdg PF10492.4 XP_011276265.1 - 1.6 9.2 4.9 0.83 10.1 1.7 1.8 1 1 1 2 2 2 0 Nrf1 activator activation site binding domain Fungal_trans PF04082.13 XP_011276266.1 - 2.5e-07 29.8 0.7 2.5e-07 29.8 0.5 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 XP_011276266.1 - 8.5e-06 25.5 9.8 1.6e-05 24.7 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain efThoc1 PF11957.3 XP_011276267.1 - 1.6e-27 96.2 25.6 1.6e-27 96.2 17.8 1.8 1 1 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Asp PF00026.18 XP_011276268.1 - 4.5e-51 173.9 0.0 6.2e-51 173.5 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 XP_011276268.1 - 0.00012 22.0 0.0 0.00031 20.7 0.0 1.8 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal RVP PF00077.15 XP_011276268.1 - 0.0011 18.8 0.0 0.44 10.4 0.0 2.5 2 0 0 2 2 2 2 Retroviral aspartyl protease gag-asp_proteas PF13975.1 XP_011276268.1 - 0.002 17.8 0.0 0.42 10.4 0.0 2.4 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 XP_011276268.1 - 0.0055 17.1 0.0 15 6.2 0.0 3.4 3 0 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.1 XP_011276268.1 - 0.074 12.5 0.0 4.1 6.9 0.0 2.6 2 1 0 2 2 2 0 Xylanase inhibitor C-terminal adh_short_C2 PF13561.1 XP_011276269.1 - 1.8e-16 60.6 0.0 2.3e-16 60.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 XP_011276269.1 - 2.1e-14 53.7 0.0 4.3e-14 52.7 0.0 1.5 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.5 XP_011276269.1 - 1.3e-05 24.9 0.0 5.8e-05 22.8 0.0 1.9 1 1 1 2 2 2 1 KR domain NAD_binding_10 PF13460.1 XP_011276269.1 - 0.0021 18.0 0.0 0.005 16.8 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding F420_oxidored PF03807.12 XP_011276269.1 - 0.024 15.0 0.2 0.12 12.8 0.0 2.2 1 1 1 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.10 XP_011276269.1 - 0.045 12.6 0.0 0.054 12.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Asp PF00026.18 XP_011276270.1 - 5.3e-58 196.7 7.0 5.3e-58 196.7 4.9 2.4 2 1 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 XP_011276270.1 - 2.8e-07 30.2 0.7 5.9e-05 22.6 0.2 3.1 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal TAXi_N PF14543.1 XP_011276270.1 - 1.4e-06 28.3 0.0 1.6e-05 24.8 0.0 2.8 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 XP_011276270.1 - 0.0081 16.6 0.2 0.38 11.2 0.0 3.0 3 0 0 3 3 3 1 Aspartyl protease zf-RING_2 PF13639.1 XP_011276271.1 - 4.4e-12 45.6 5.1 4.4e-10 39.2 0.8 2.3 2 0 0 2 2 2 2 Ring finger domain zf-rbx1 PF12678.2 XP_011276271.1 - 5.1e-10 39.3 0.8 1.7e-07 31.2 0.1 2.3 2 0 0 2 2 2 2 RING-H2 zinc finger zf-C3HC4 PF00097.20 XP_011276271.1 - 2.6e-06 26.9 4.0 6.8e-06 25.6 0.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 XP_011276271.1 - 5.6e-06 26.2 5.3 6.9e-06 25.9 0.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 XP_011276271.1 - 8.1e-06 25.4 2.2 6.5e-05 22.5 0.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 XP_011276271.1 - 0.00017 21.2 3.0 0.00046 19.8 0.5 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 XP_011276271.1 - 0.00043 20.0 1.0 0.0013 18.5 0.2 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 XP_011276271.1 - 0.0028 17.5 1.4 0.0028 17.5 1.0 1.7 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 XP_011276271.1 - 0.0058 16.3 0.4 0.029 14.0 0.2 2.2 1 1 0 1 1 1 1 RING-type zinc-finger zf-P11 PF03854.9 XP_011276271.1 - 0.79 9.2 2.8 0.64 9.5 0.5 1.9 2 0 0 2 2 2 0 P-11 zinc finger FANCL_C PF11793.3 XP_011276271.1 - 0.85 9.6 3.8 10 6.1 0.8 2.7 2 1 0 2 2 2 0 FANCL C-terminal domain RINGv PF12906.2 XP_011276271.1 - 0.96 9.5 3.6 1.4 8.9 0.7 2.3 2 0 0 2 2 2 0 RING-variant domain E1-E2_ATPase PF00122.15 XP_011276272.1 - 3.3e-65 219.3 8.2 6.7e-65 218.3 5.7 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 XP_011276272.1 - 4.6e-23 82.7 0.1 9.2e-23 81.7 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 XP_011276272.1 - 2.6e-14 53.8 0.0 8.5e-14 52.1 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 XP_011276272.1 - 1.4e-11 43.7 0.6 4.6e-11 42.0 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 XP_011276272.1 - 0.0053 16.3 0.1 0.013 15.1 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 XP_011276272.1 - 0.024 14.6 0.0 0.058 13.3 0.0 1.6 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit SIS_2 PF13580.1 XP_011276272.1 - 0.07 12.8 0.0 0.26 11.0 0.0 1.9 1 0 0 1 1 1 0 SIS domain PUF PF00806.14 XP_011276273.1 - 6e-65 211.2 17.6 5e-08 32.0 0.1 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat MgtE_N PF03448.12 XP_011276273.1 - 0.092 13.0 0.1 0.24 11.7 0.1 1.7 1 0 0 1 1 1 0 MgtE intracellular N domain Ras PF00071.17 XP_011276274.1 - 4.2e-51 172.5 0.0 4.8e-51 172.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 XP_011276274.1 - 6.7e-16 58.8 0.0 9.1e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 XP_011276274.1 - 5.1e-09 35.6 0.0 6.5e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.4 XP_011276274.1 - 0.0013 18.2 0.0 1.7 8.1 0.0 2.3 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 XP_011276274.1 - 0.03 13.5 0.0 0.046 12.9 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 XP_011276274.1 - 0.078 12.9 0.0 0.1 12.5 0.0 1.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase GTP_EFTU PF00009.22 XP_011276274.1 - 0.11 11.9 0.0 0.65 9.3 0.0 2.0 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain NST1 PF13945.1 XP_011276275.1 - 2.1e-26 93.1 20.6 2.1e-26 93.1 14.3 8.7 2 1 5 8 8 8 1 Salt tolerance down-regulator FHA PF00498.21 XP_011276276.1 - 1.2e-12 47.7 0.0 2.6e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 XP_011276276.1 - 2e-06 27.4 12.3 3.5e-06 26.7 8.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-Apc11 PF12861.2 XP_011276276.1 - 0.014 15.2 6.1 0.03 14.1 4.2 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 XP_011276276.1 - 0.078 13.0 7.9 0.16 12.0 5.5 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4 PF00097.20 XP_011276276.1 - 0.13 11.9 13.2 0.25 11.0 9.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Sec_GG PF07549.9 XP_011276276.1 - 0.13 11.4 0.3 0.28 10.4 0.2 1.5 1 0 0 1 1 1 0 SecD/SecF GG Motif PHD PF00628.24 XP_011276276.1 - 0.21 11.2 9.6 0.46 10.2 6.7 1.6 1 0 0 1 1 1 0 PHD-finger zf-FPG_IleRS PF06827.9 XP_011276276.1 - 0.36 10.5 6.9 1.3 8.7 4.8 2.0 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS zf-RING_5 PF14634.1 XP_011276276.1 - 1.3 8.8 11.1 2.2 8.0 7.7 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Na_trans_assoc PF06512.8 XP_011276276.1 - 2.5 7.9 11.6 2.5 7.9 3.6 2.4 2 0 0 2 2 2 0 Sodium ion transport-associated zf-C3HC4_2 PF13923.1 XP_011276276.1 - 4.3 7.4 15.1 7.3 6.7 10.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2417 PF10329.4 XP_011276277.1 - 5.6e-66 222.2 1.7 7.8e-66 221.7 1.2 1.1 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_6 PF12697.2 XP_011276277.1 - 7.1e-11 42.4 0.0 9.7e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 XP_011276277.1 - 0.00016 21.3 0.0 0.00024 20.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 XP_011276277.1 - 0.00088 19.0 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family AMP-binding PF00501.23 XP_011276278.1 - 7.4e-49 166.2 0.0 1e-25 90.0 0.0 4.0 2 2 0 2 2 2 2 AMP-binding enzyme DMAP_binding PF06464.6 XP_011276278.1 - 8.9e-10 39.1 0.1 2.6e-09 37.6 0.1 1.8 1 0 0 1 1 1 1 DMAP1-binding Domain NST1 PF13945.1 XP_011276278.1 - 0.076 13.0 0.3 0.15 12.1 0.2 1.4 1 0 0 1 1 1 0 Salt tolerance down-regulator Nucleoporin_FG PF13634.1 XP_011276279.1 - 9.7e-11 41.9 216.4 0.0012 19.0 14.4 8.2 2 1 6 8 8 8 5 Nucleoporin FG repeat region Nup_retrotrp_bd PF10599.4 XP_011276279.1 - 0.0011 19.6 13.9 0.0011 19.6 9.6 10.1 2 1 5 8 8 8 1 Retro-transposon transporting motif Pkinase PF00069.20 XP_011276280.1 - 4.1e-68 229.3 0.0 8.5e-68 228.3 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011276280.1 - 3e-50 170.7 0.0 6e-48 163.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Ras_bdg_2 PF14847.1 XP_011276280.1 - 3.5e-27 94.3 0.0 9.5e-27 92.9 0.0 1.8 1 0 0 1 1 1 1 Ras-binding domain of Byr2 Kinase-like PF14531.1 XP_011276280.1 - 0.00043 19.3 0.0 0.0039 16.1 0.0 2.2 2 0 0 2 2 2 1 Kinase-like SAM_2 PF07647.12 XP_011276280.1 - 0.0018 18.0 0.2 0.0047 16.7 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 XP_011276280.1 - 0.014 15.5 0.4 0.033 14.3 0.3 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Clathrin-link PF09268.5 XP_011276280.1 - 0.028 13.4 0.2 0.11 11.6 0.2 1.9 2 0 0 2 2 2 0 Clathrin, heavy-chain linker Kdo PF06293.9 XP_011276280.1 - 0.065 12.2 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Metallophos PF00149.23 XP_011276282.1 - 2.5e-13 49.8 0.5 6.9e-13 48.4 0.3 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Atg14 PF10186.4 XP_011276283.1 - 1.1e-10 40.9 10.7 2.4e-10 39.8 7.4 1.5 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 FAM194 PF14977.1 XP_011276283.1 - 0.095 11.6 2.9 0.15 11.0 2.0 1.3 1 0 0 1 1 1 0 FAM194 protein Folliculin PF11704.3 XP_011276284.1 - 1.8e-41 141.5 4.7 4.2e-41 140.3 3.2 1.6 1 1 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport Rpr2 PF04032.11 XP_011276284.1 - 0.017 14.9 0.8 0.017 14.9 0.6 1.8 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain AP_endonuc_2 PF01261.19 XP_011276284.1 - 0.068 12.4 0.0 0.099 11.9 0.0 1.2 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel FAM101 PF15068.1 XP_011276284.1 - 0.093 12.1 0.3 0.15 11.4 0.2 1.3 1 0 0 1 1 1 0 FAM101 family PALP PF00291.20 XP_011276285.1 - 8.6e-59 199.2 0.0 1.1e-58 198.9 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme SMC_N PF02463.14 XP_011276286.1 - 2e-47 161.2 60.4 1.3e-46 158.6 41.9 2.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 XP_011276286.1 - 1e-28 99.7 0.5 6.5e-28 97.1 0.0 2.8 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 XP_011276286.1 - 6e-09 36.5 41.0 6e-09 36.5 28.4 7.3 2 2 1 3 3 3 1 AAA domain AAA_21 PF13304.1 XP_011276286.1 - 1.3e-08 35.2 19.2 6.2e-07 29.6 1.3 6.2 2 2 3 5 5 5 2 AAA domain AAA_29 PF13555.1 XP_011276286.1 - 2.9e-08 33.1 0.1 6.3e-08 32.0 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 XP_011276286.1 - 0.0023 17.8 0.1 0.029 14.2 0.0 2.9 3 0 0 3 3 3 1 Putative exonuclease SbcCD, C subunit TMP_2 PF06791.8 XP_011276286.1 - 0.0084 15.7 8.2 0.11 12.1 0.1 3.4 3 0 0 3 3 3 2 Prophage tail length tape measure protein Reo_sigmaC PF04582.7 XP_011276286.1 - 0.06 12.5 27.0 0.086 12.0 0.7 5.0 4 1 2 6 6 6 0 Reovirus sigma C capsid protein WD40 PF00400.27 XP_011276287.1 - 5.9e-47 155.9 21.3 4.3e-09 35.9 0.2 8.0 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 XP_011276287.1 - 3.7e-07 28.6 7.3 0.068 11.2 0.1 4.3 1 1 2 3 3 3 3 Nucleoporin Nup120/160 F-box-like PF12937.2 XP_011276287.1 - 4.8e-07 29.4 0.0 1e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 XP_011276287.1 - 1.6e-06 27.6 0.1 1.6e-06 27.6 0.0 1.9 2 0 0 2 2 2 1 F-box domain BBS2_Mid PF14783.1 XP_011276287.1 - 7.6e-05 22.4 0.2 3.7 7.3 0.0 4.2 1 1 2 3 3 3 3 Ciliary BBSome complex subunit 2, middle region PRANC PF09372.5 XP_011276287.1 - 0.0012 18.7 0.6 0.0036 17.2 0.4 1.9 1 0 0 1 1 1 1 PRANC domain Med3 PF11593.3 XP_011276287.1 - 0.0015 17.8 5.5 0.0024 17.2 3.8 1.3 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal PQQ_2 PF13360.1 XP_011276287.1 - 0.0057 16.1 0.1 3.2 7.1 0.0 2.7 1 1 2 3 3 3 2 PQQ-like domain Kelch_6 PF13964.1 XP_011276287.1 - 0.046 13.9 0.3 29 5.0 0.0 3.7 3 0 0 3 3 3 0 Kelch motif BAF1_ABF1 PF04684.8 XP_011276287.1 - 1 8.1 9.3 1.9 7.2 6.5 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Abhydrolase_6 PF12697.2 XP_011276288.1 - 1.3e-32 113.5 0.0 1.6e-32 113.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 XP_011276288.1 - 6.7e-16 58.5 0.0 1.3e-15 57.6 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 XP_011276288.1 - 2.9e-12 46.5 0.0 6.6e-12 45.3 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 XP_011276288.1 - 2.8e-11 43.4 0.0 4.4e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.15 XP_011276288.1 - 0.00046 20.4 0.0 0.0013 19.0 0.0 1.7 2 0 0 2 2 2 1 Thioesterase domain Hydrolase_4 PF12146.3 XP_011276288.1 - 0.0037 17.0 0.0 0.008 16.0 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase UPF0227 PF05728.7 XP_011276288.1 - 0.012 15.3 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) FMN_red PF03358.10 XP_011276288.1 - 0.09 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 NADPH-dependent FMN reductase AIG1 PF04548.11 XP_011276289.1 - 0.098 11.7 1.6 0.16 11.0 0.5 1.7 1 1 1 2 2 2 0 AIG1 family CRC_subunit PF08624.5 XP_011276290.1 - 8.2e-43 145.6 0.6 1.7e-42 144.6 0.1 1.7 2 0 0 2 2 2 1 Chromatin remodelling complex Rsc7/Swp82 subunit Lectin_leg-like PF03388.8 XP_011276291.1 - 2.2e-34 118.5 0.2 4.1e-34 117.7 0.2 1.4 1 0 0 1 1 1 1 Legume-like lectin family CHASE3 PF05227.8 XP_011276291.1 - 0.013 15.1 0.3 0.029 14.0 0.2 1.5 1 0 0 1 1 1 0 CHASE3 domain Snapin_Pallidin PF14712.1 XP_011276291.1 - 0.016 15.5 2.7 0.016 15.5 1.9 2.4 2 0 0 2 2 2 0 Snapin/Pallidin LOH1CR12 PF10158.4 XP_011276291.1 - 0.032 14.0 4.4 0.027 14.2 1.8 1.8 1 1 0 1 1 1 0 Tumour suppressor protein NPV_P10 PF05531.7 XP_011276291.1 - 0.055 13.7 13.1 1.2 9.4 0.2 3.7 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein SF-assemblin PF06705.6 XP_011276291.1 - 0.1 11.7 19.6 0.058 12.5 8.0 2.1 1 1 0 2 2 2 0 SF-assemblin/beta giardin Reo_sigmaC PF04582.7 XP_011276291.1 - 0.2 10.7 4.3 0.32 10.1 3.0 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein YjgP_YjgQ PF03739.9 XP_011276291.1 - 0.33 9.6 4.4 0.67 8.6 2.8 1.6 1 1 0 1 1 1 0 Predicted permease YjgP/YjgQ family Lipoprotein_6 PF01441.14 XP_011276291.1 - 0.46 10.3 13.1 0.13 12.0 6.8 1.9 2 1 0 2 2 1 0 Lipoprotein FlxA PF14282.1 XP_011276291.1 - 0.53 10.2 13.2 0.14 12.1 6.1 2.3 1 1 0 1 1 1 0 FlxA-like protein Noelin-1 PF12308.3 XP_011276291.1 - 0.53 10.1 2.7 1.1 9.1 0.1 2.5 1 1 1 2 2 2 0 Neurogenesis glycoprotein Ax_dynein_light PF10211.4 XP_011276291.1 - 1.2 8.9 12.6 0.91 9.3 6.0 2.1 1 1 1 2 2 2 0 Axonemal dynein light chain PhoU PF01895.14 XP_011276291.1 - 1.4 9.4 7.9 0.91 10.0 0.9 2.9 2 1 1 3 3 2 0 PhoU domain Uds1 PF15456.1 XP_011276291.1 - 2.4 8.1 7.0 1.3 8.9 3.1 1.9 1 1 1 2 2 2 0 Up-regulated During Septation TMF_DNA_bd PF12329.3 XP_011276291.1 - 3.6 7.4 24.9 0.024 14.4 3.5 3.7 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Baculo_PEP_C PF04513.7 XP_011276291.1 - 5.4 6.8 22.4 5.6 6.7 13.5 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.7 XP_011276291.1 - 5.7 6.7 13.9 0.46 10.2 2.2 2.9 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) Osmo_CC PF08946.5 XP_011276291.1 - 7.1 6.7 9.5 2.1 8.4 0.7 3.7 3 1 0 3 3 3 0 Osmosensory transporter coiled coil ACCA PF03255.9 XP_011276291.1 - 7.7 6.0 10.0 1.2 8.7 2.3 2.9 2 1 2 4 4 4 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Rdx PF10262.4 XP_011276292.1 - 9.8e-30 102.4 0.1 1.4e-29 101.9 0.1 1.2 1 0 0 1 1 1 1 Rdx family FACT-Spt16_Nlob PF14826.1 XP_011276292.1 - 0.11 11.9 1.9 0.16 11.5 1.3 1.2 1 0 0 1 1 1 0 FACT complex subunit SPT16 N-terminal lobe domain RhoGAP PF00620.22 XP_011276293.1 - 2.2e-14 53.3 2.2 6.6e-14 51.7 0.1 2.5 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.18 XP_011276293.1 - 8.2e-13 48.3 3.1 2.3e-12 46.9 0.0 3.4 4 0 0 4 4 4 1 Fes/CIP4, and EFC/F-BAR homology domain DEP PF00610.16 XP_011276293.1 - 2.7e-10 39.8 0.0 5.4e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF1981 PF09324.5 XP_011276293.1 - 0.057 12.9 0.2 0.17 11.4 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1981) Mit_KHE1 PF10173.4 XP_011276293.1 - 1.7 8.4 6.7 3.3 7.5 0.0 2.7 3 0 0 3 3 3 0 Mitochondrial K+-H+ exchange-related Cor1 PF04803.7 XP_011276293.1 - 7 6.4 15.5 0.037 13.7 2.9 3.0 4 0 0 4 4 4 0 Cor1/Xlr/Xmr conserved region AreA_N PF07573.6 XP_011276294.1 - 0.043 14.3 1.1 0.65 10.6 0.1 2.5 2 0 0 2 2 2 0 Nitrogen regulatory protein AreA N terminus F-box PF00646.28 XP_011276296.1 - 0.00037 20.0 0.8 0.004 16.7 0.2 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 XP_011276296.1 - 0.0038 16.9 0.4 0.0076 15.9 0.3 1.5 1 0 0 1 1 1 1 F-box-like NB-ARC PF00931.17 XP_011276296.1 - 0.063 12.1 0.3 0.52 9.1 0.1 1.9 1 1 1 2 2 2 0 NB-ARC domain LRR_4 PF12799.2 XP_011276297.1 - 0.86 9.3 12.5 0.7 9.5 0.1 5.2 5 3 0 5 5 5 0 Leucine Rich repeats (2 copies) AA_permease PF00324.16 XP_011276298.1 - 5.6e-143 476.7 41.5 6.4e-143 476.5 28.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 XP_011276298.1 - 5e-43 147.2 42.8 6.5e-43 146.8 29.6 1.0 1 0 0 1 1 1 1 Amino acid permease dsrm PF00035.20 XP_011276299.1 - 3.6e-09 37.0 0.0 0.0009 19.7 0.0 2.8 2 0 0 2 2 2 2 Double-stranded RNA binding motif Ribonuclease_3 PF00636.21 XP_011276299.1 - 0.011 16.1 0.1 0.049 14.0 0.0 2.1 2 0 0 2 2 2 0 Ribonuclease III domain DUF2570 PF10828.3 XP_011276299.1 - 0.082 12.5 0.5 0.19 11.3 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) PAT1 PF09770.4 XP_011276299.1 - 8.9 4.4 40.1 12 3.9 27.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AA_permease PF00324.16 XP_011276300.1 - 3.2e-84 282.9 42.3 3.9e-84 282.6 29.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 XP_011276300.1 - 1e-11 44.0 44.4 1.9e-11 43.1 30.8 1.4 1 1 0 1 1 1 1 Amino acid permease Sugar_tr PF00083.19 XP_011276301.1 - 7.7e-127 423.5 22.5 8.9e-127 423.3 15.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 XP_011276301.1 - 3.1e-26 91.9 27.6 3.8e-21 75.2 6.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 XP_011276301.1 - 0.00014 20.0 6.1 0.00016 19.9 0.1 2.1 2 0 0 2 2 2 1 Transmembrane secretion effector DUF2530 PF10745.4 XP_011276301.1 - 0.14 12.1 2.2 0.17 11.8 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) DUF2427 PF10348.4 XP_011276301.1 - 7.8 6.1 7.5 2.9 7.5 0.9 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF2427) SID PF11778.3 XP_011276302.1 - 2.3e-14 53.4 5.8 2.3e-14 53.4 4.0 2.3 1 1 1 2 2 2 1 Septation initiation Lipoprotein_20 PF13942.1 XP_011276302.1 - 0.26 10.7 11.1 0.098 12.1 0.7 2.5 1 1 1 2 2 2 0 YfhG lipoprotein Reo_sigmaC PF04582.7 XP_011276302.1 - 0.83 8.7 9.8 6.7 5.7 0.9 3.1 1 1 2 4 4 4 0 Reovirus sigma C capsid protein V_ATPase_I PF01496.14 XP_011276302.1 - 1.7 6.3 18.9 1.2 6.8 8.5 2.2 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Macoilin PF09726.4 XP_011276302.1 - 3.8 5.6 30.7 5 5.2 21.3 1.1 1 0 0 1 1 1 0 Transmembrane protein AA_permease PF00324.16 XP_011276303.1 - 6.9e-95 318.1 40.4 8.4e-95 317.8 28.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 XP_011276303.1 - 1.9e-23 82.6 46.5 2.2e-23 82.4 32.2 1.0 1 0 0 1 1 1 1 Amino acid permease DUF1772 PF08592.6 XP_011276303.1 - 0.0042 16.8 0.3 0.0042 16.8 0.2 4.0 2 1 1 4 4 4 2 Domain of unknown function (DUF1772) MFS_1 PF07690.11 XP_011276304.1 - 3.5e-34 118.0 42.4 3.5e-34 118.0 29.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 XP_011276304.1 - 3.7e-07 28.7 6.0 6.5e-07 27.9 4.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DnaJ PF00226.26 XP_011276305.1 - 9.4e-26 89.3 1.2 4.4e-25 87.2 0.9 2.3 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.3 XP_011276305.1 - 1.9e-07 30.9 13.9 5e-07 29.6 3.9 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 XP_011276305.1 - 2.4e-07 30.7 7.4 0.0047 17.0 1.3 3.0 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 XP_011276305.1 - 6.5e-07 29.3 12.9 1.2e-05 25.2 2.9 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 XP_011276305.1 - 3.2e-05 24.0 10.6 0.012 15.8 1.5 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 XP_011276305.1 - 3.9e-05 23.3 7.4 0.042 13.7 0.7 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_4 PF13894.1 XP_011276305.1 - 0.00017 21.6 6.7 0.054 13.8 0.2 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 XP_011276305.1 - 0.21 11.9 2.4 6.2 7.3 0.2 2.7 2 0 0 2 2 2 0 Zinc-finger double domain LIM PF00412.17 XP_011276305.1 - 0.77 9.8 4.4 5.9 7.0 0.4 2.5 2 0 0 2 2 2 0 LIM domain G-patch PF01585.18 XP_011276306.1 - 5.1e-13 48.5 0.6 1.5e-12 47.0 0.4 1.9 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 XP_011276306.1 - 0.0021 17.8 0.2 0.0021 17.8 0.2 3.1 3 0 0 3 3 3 1 DExH-box splicing factor binding site Peptidase_C54 PF03416.14 XP_011276307.1 - 3.1e-97 325.0 0.0 4.2e-97 324.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 Ssu72 PF04722.8 XP_011276308.1 - 1.8e-74 249.2 0.0 2e-74 249.1 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein Amidohydro_1 PF01979.15 XP_011276309.1 - 4e-44 151.6 0.0 5e-44 151.3 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 XP_011276309.1 - 2.4e-05 23.7 0.2 0.0058 15.8 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 XP_011276309.1 - 0.00043 20.0 0.1 0.0011 18.7 0.0 1.8 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_4 PF13147.1 XP_011276309.1 - 0.00048 20.2 0.1 0.19 11.7 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase FAINT PF04385.10 XP_011276310.1 - 0.41 10.5 5.4 0.067 13.0 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function, DUF529 POP1 PF06978.6 XP_011276311.1 - 3.7e-62 209.3 13.0 3.7e-62 209.3 9.0 2.2 2 0 0 2 2 2 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 XP_011276311.1 - 1e-29 102.1 1.0 3.1e-29 100.6 0.7 1.9 1 0 0 1 1 1 1 POPLD (NUC188) domain GCV_T_C PF08669.6 XP_011276311.1 - 0.1 12.6 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 Glycine cleavage T-protein C-terminal barrel domain Adenylsucc_synt PF00709.16 XP_011276312.1 - 5.3e-167 555.7 0.0 6e-167 555.5 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Glyco_transf_22 PF03901.12 XP_011276313.1 - 5.4e-72 243.0 31.9 6.8e-72 242.7 22.1 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family GRIM-19 PF06212.7 XP_011276314.1 - 5.8e-30 103.6 0.1 6.9e-30 103.4 0.1 1.0 1 0 0 1 1 1 1 GRIM-19 protein Hydrolase_6 PF13344.1 XP_011276315.1 - 2.3e-31 107.6 0.0 4.5e-31 106.7 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 XP_011276315.1 - 7.6e-16 57.5 0.0 1.6e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 XP_011276315.1 - 1.5e-15 58.2 0.0 1.8e-15 57.9 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 XP_011276315.1 - 2.4e-05 24.6 0.1 0.38 10.9 0.0 2.7 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.9 XP_011276315.1 - 0.0013 18.2 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 HAD superfamily, subfamily IIIB (Acid phosphatase) PGP_phosphatase PF09419.5 XP_011276315.1 - 0.11 11.7 0.0 0.36 10.1 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase Peripla_BP_4 PF13407.1 XP_011276315.1 - 0.12 11.7 0.0 0.51 9.6 0.0 1.9 1 1 1 2 2 2 0 Periplasmic binding protein domain MgsA_C PF12002.3 XP_011276316.1 - 2.1e-52 177.1 0.0 3.3e-52 176.5 0.0 1.2 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 XP_011276316.1 - 3.5e-16 59.5 0.0 7.4e-16 58.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 XP_011276316.1 - 3.7e-14 52.3 0.0 2.8e-13 49.4 0.0 2.2 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 XP_011276316.1 - 1.1e-07 31.8 0.0 2.6e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 XP_011276316.1 - 2.5e-07 30.5 0.1 7.6e-06 25.6 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 XP_011276316.1 - 3e-05 24.1 0.1 0.00011 22.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 XP_011276316.1 - 4.2e-05 24.3 0.0 9.6e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 XP_011276316.1 - 6.4e-05 22.4 0.0 0.41 10.1 0.0 2.3 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_18 PF13238.1 XP_011276316.1 - 0.00015 22.0 0.1 0.00059 20.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 XP_011276316.1 - 0.00038 20.4 0.0 0.0054 16.7 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.17 XP_011276316.1 - 0.00082 19.5 0.0 0.0023 18.0 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_19 PF13245.1 XP_011276316.1 - 0.0016 18.1 0.0 0.0038 16.9 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain Sigma54_activ_2 PF14532.1 XP_011276316.1 - 0.0019 18.2 0.0 0.0069 16.4 0.0 1.9 2 0 0 2 2 2 1 Sigma-54 interaction domain DUF815 PF05673.8 XP_011276316.1 - 0.0021 17.0 0.0 0.0037 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ABC_tran PF00005.22 XP_011276316.1 - 0.0025 18.0 0.0 0.1 12.9 0.0 2.6 1 1 0 1 1 1 1 ABC transporter ResIII PF04851.10 XP_011276316.1 - 0.0039 17.0 0.1 0.11 12.3 0.1 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit Rad17 PF03215.10 XP_011276316.1 - 0.0083 14.8 0.4 1.7 7.2 0.2 2.1 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_3 PF07726.6 XP_011276316.1 - 0.016 14.7 0.0 0.031 13.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SKI PF01202.17 XP_011276316.1 - 0.018 14.8 0.0 0.034 14.0 0.0 1.4 1 0 0 1 1 1 0 Shikimate kinase Mg_chelatase PF01078.16 XP_011276316.1 - 0.024 13.8 0.0 0.12 11.4 0.0 2.0 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI DNA_pol3_delta2 PF13177.1 XP_011276316.1 - 0.028 14.0 0.0 0.31 10.7 0.0 2.1 1 1 1 2 2 2 0 DNA polymerase III, delta subunit TIP49 PF06068.8 XP_011276316.1 - 0.039 12.6 0.0 0.24 10.0 0.0 1.9 2 0 0 2 2 2 0 TIP49 C-terminus NTPase_1 PF03266.10 XP_011276316.1 - 0.044 13.4 0.0 0.099 12.3 0.0 1.6 1 0 0 1 1 1 0 NTPase IstB_IS21 PF01695.12 XP_011276316.1 - 0.059 12.7 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Zeta_toxin PF06414.7 XP_011276316.1 - 0.097 11.7 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.1 XP_011276316.1 - 0.12 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 XP_011276316.1 - 0.17 11.8 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain PRP21_like_P PF12230.3 XP_011276316.1 - 0.4 10.1 4.4 1.1 8.7 0.0 2.3 2 0 0 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein DUF4611 PF15387.1 XP_011276316.1 - 1.8 8.7 6.0 3.7 7.7 4.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Hpt PF01627.18 XP_011276317.1 - 4.9e-11 42.4 0.1 6.5e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 Hpt domain RabGAP-TBC PF00566.13 XP_011276318.1 - 1.7e-34 119.1 18.6 1.1e-33 116.4 12.9 2.1 1 1 0 1 1 1 1 Rab-GTPase-TBC domain DUF3548 PF12068.3 XP_011276318.1 - 0.00053 19.3 0.2 0.25 10.6 0.0 2.7 1 1 1 2 2 2 2 Domain of unknown function (DUF3548) LUC7 PF03194.10 XP_011276318.1 - 0.04 13.4 0.2 0.086 12.3 0.1 1.4 1 0 0 1 1 1 0 LUC7 N_terminus Glyco_hydro_4C PF11975.3 XP_011276318.1 - 0.065 13.0 0.4 0.12 12.1 0.3 1.5 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase C-terminal domain FAR1 PF03101.10 XP_011276319.1 - 0.0052 17.2 0.2 0.0052 17.2 0.1 2.8 2 1 0 2 2 2 1 FAR1 DNA-binding domain PAT1 PF09770.4 XP_011276319.1 - 0.27 9.4 67.7 0.36 9.0 47.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PAPA-1 PF04795.7 XP_011276320.1 - 1.4e-16 60.9 5.5 1.4e-16 60.9 3.8 2.5 3 0 0 3 3 3 1 PAPA-1-like conserved region CRT10 PF08728.5 XP_011276320.1 - 2.7 5.8 7.8 3.2 5.6 5.4 1.1 1 0 0 1 1 1 0 CRT10 LIM_bind PF01803.11 XP_011276321.1 - 5.1e-50 169.8 0.1 5.1e-50 169.8 0.1 4.1 2 2 3 5 5 5 1 LIM-domain binding protein Neugrin PF06413.6 XP_011276323.1 - 2.3e-10 40.7 1.5 2.3e-10 40.7 1.0 1.8 2 0 0 2 2 2 1 Neugrin Sigma70_r4 PF04545.11 XP_011276323.1 - 0.0033 16.7 0.1 0.0064 15.7 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.1 XP_011276323.1 - 0.0034 16.9 0.2 0.04 13.5 0.0 2.6 3 0 0 3 3 3 1 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.1 XP_011276323.1 - 0.0052 15.9 0.0 0.011 14.8 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_24 PF13412.1 XP_011276323.1 - 0.025 13.9 0.1 0.12 11.8 0.0 2.1 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_11 PF08279.7 XP_011276323.1 - 0.027 14.1 0.0 0.081 12.5 0.0 1.8 1 0 0 1 1 1 0 HTH domain HTH_DeoR PF08220.7 XP_011276323.1 - 0.042 13.3 0.0 0.092 12.2 0.0 1.5 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_32 PF13565.1 XP_011276323.1 - 0.12 13.2 0.7 0.43 11.4 0.0 2.3 3 0 0 3 3 3 0 Homeodomain-like domain VID27 PF08553.5 XP_011276324.1 - 1.5e-293 975.9 18.7 1.8e-293 975.7 13.0 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein DUF2422 PF10337.4 XP_011276325.1 - 1.4e-10 40.5 16.0 1.7e-06 27.1 0.7 4.8 4 1 1 5 5 5 2 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 XP_011276325.1 - 4.3e-07 29.8 6.1 4.3e-07 29.8 4.3 2.5 2 0 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.3 XP_011276325.1 - 4.2e-06 25.6 7.8 0.00026 19.7 0.2 2.9 3 0 0 3 3 3 2 Aluminium activated malate transporter FUSC PF04632.7 XP_011276325.1 - 0.00046 18.7 0.3 0.012 14.0 0.0 2.4 3 0 0 3 3 3 1 Fusaric acid resistance protein family DUF2421 PF10334.4 XP_011276325.1 - 0.00052 19.7 0.5 0.0014 18.2 0.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) KH_1 PF00013.24 XP_011276327.1 - 5.2e-10 38.8 1.7 4.5e-08 32.6 0.2 2.4 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 XP_011276327.1 - 2.3e-06 27.1 0.6 5.6e-05 22.6 0.1 2.5 2 0 0 2 2 2 1 KH domain KH_2 PF07650.12 XP_011276327.1 - 0.013 15.0 1.2 0.02 14.4 0.2 1.8 2 0 0 2 2 2 0 KH domain HSP70 PF00012.15 XP_011276328.1 - 2.8e-234 778.5 7.6 3.1e-234 778.4 5.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 XP_011276328.1 - 2.2e-17 62.6 1.2 3.7e-16 58.6 0.2 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 XP_011276328.1 - 0.00074 19.1 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain VP4_haemagglut PF00426.13 XP_011276328.1 - 0.017 13.1 0.2 0.027 12.4 0.2 1.2 1 0 0 1 1 1 0 Outer Capsid protein VP4 (Hemagglutinin) RPA PF10134.4 XP_011276328.1 - 0.018 14.3 0.4 0.045 13.0 0.0 1.8 2 0 0 2 2 2 0 Replication initiator protein A DUF2603 PF10788.4 XP_011276328.1 - 0.032 13.9 0.1 0.11 12.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2603) StbA PF06406.6 XP_011276328.1 - 0.044 12.7 0.0 0.19 10.6 0.0 2.0 2 0 0 2 2 2 0 StbA protein RIO1 PF01163.17 XP_011276329.1 - 8.1e-42 142.7 0.6 1.4e-41 141.9 0.4 1.4 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.6 XP_011276329.1 - 6.4e-33 112.6 0.1 1.9e-32 111.1 0.0 1.9 2 0 0 2 2 2 1 Rio2, N-terminal APH PF01636.18 XP_011276329.1 - 0.00045 20.0 0.0 0.11 12.1 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 XP_011276329.1 - 0.0019 17.3 0.0 0.021 13.8 0.0 2.2 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2745 PF10922.3 XP_011276329.1 - 0.09 12.7 0.6 0.27 11.1 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2745) Astro_capsid PF03115.9 XP_011276329.1 - 2.8 6.1 6.6 3.7 5.6 4.6 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Nop14 PF04147.7 XP_011276329.1 - 3.1 5.6 22.4 4.1 5.1 15.5 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.5 XP_011276329.1 - 6.6 5.6 18.9 13 4.6 13.1 1.4 1 0 0 1 1 1 0 BUD22 Rick_17kDa_Anti PF05433.10 XP_011276330.1 - 0.0021 17.6 20.4 0.0021 17.6 14.1 3.9 4 1 0 4 4 4 1 Glycine zipper 2TM domain Rtt106 PF08512.7 XP_011276331.1 - 9.2e-26 89.6 0.4 9.2e-26 89.6 0.3 1.8 2 0 0 2 2 2 1 Histone chaperone Rttp106-like PAP2 PF01569.16 XP_011276333.1 - 3.6e-21 75.1 1.0 6.9e-21 74.2 0.7 1.4 1 0 0 1 1 1 1 PAP2 superfamily FUSC_2 PF13515.1 XP_011276333.1 - 0.12 12.2 1.8 0.17 11.8 0.1 2.0 2 0 0 2 2 2 0 Fusaric acid resistance protein-like PAP2_C PF14360.1 XP_011276333.1 - 0.23 11.7 5.6 0.29 11.4 0.4 2.4 2 0 0 2 2 2 0 PAP2 superfamily C-terminal VPS11_C PF12451.3 XP_011276334.1 - 5.3e-13 48.5 0.1 1.9e-12 46.8 0.1 2.0 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal Clathrin PF00637.15 XP_011276334.1 - 1.2e-08 34.6 5.6 1.2e-08 34.6 3.9 3.2 3 0 0 3 3 3 1 Region in Clathrin and VPS UPF0564 PF10595.4 XP_011276334.1 - 0.013 14.4 1.1 0.017 14.0 0.2 1.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0564 zf-rbx1 PF12678.2 XP_011276334.1 - 0.24 11.5 4.7 0.54 10.4 3.3 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_2 PF13639.1 XP_011276334.1 - 0.39 10.5 8.8 0.92 9.3 6.1 1.7 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.1 XP_011276334.1 - 0.85 9.6 8.5 1.7 8.7 5.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 XP_011276334.1 - 1.1 9.0 10.4 2.2 8.0 7.2 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.20 XP_011276334.1 - 8.2 6.1 10.0 17 5.1 6.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RRS1 PF04939.7 XP_011276335.1 - 2.9e-56 189.4 8.4 2.9e-56 189.4 5.8 2.1 2 0 0 2 2 2 1 Ribosome biogenesis regulatory protein (RRS1) RhoGEF PF00621.15 XP_011276335.1 - 5.7e-29 101.2 5.9 5.7e-29 101.2 4.1 3.4 3 1 0 3 3 3 1 RhoGEF domain SWIB PF02201.13 XP_011276335.1 - 3.1e-28 97.2 0.2 1.1e-27 95.5 0.1 2.0 1 0 0 1 1 1 1 SWIB/MDM2 domain Membr_traf_MHD PF10540.4 XP_011276336.1 - 2.4e-13 50.0 0.0 1.2e-12 47.8 0.0 2.3 1 0 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 XP_011276336.1 - 4.4e-12 45.6 0.0 9.9e-12 44.5 0.0 1.7 1 0 0 1 1 1 1 C2 domain GRAM PF02893.15 XP_011276337.1 - 6.2e-20 70.4 0.0 1.3e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 GRAM domain DUF2273 PF10031.4 XP_011276337.1 - 0.56 9.8 2.1 0.93 9.1 1.5 1.3 1 0 0 1 1 1 0 Small integral membrane protein (DUF2273) Sulfate_transp PF00916.15 XP_011276338.1 - 1.2e-53 181.9 8.8 1.2e-53 181.9 6.1 1.9 2 0 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 XP_011276338.1 - 3.7e-27 93.7 5.0 1e-26 92.4 3.5 1.8 1 0 0 1 1 1 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 XP_011276338.1 - 1.3e-16 60.0 0.0 2.6e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 STAS domain LexA_DNA_bind PF01726.11 XP_011276338.1 - 0.096 12.2 0.0 0.22 11.0 0.0 1.6 1 0 0 1 1 1 0 LexA DNA binding domain RRM_1 PF00076.17 XP_011276339.1 - 5.1e-14 51.6 0.0 3.5e-10 39.3 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 XP_011276339.1 - 3e-06 27.1 0.0 1.6e-05 24.8 0.0 2.2 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) SNARE PF05739.14 XP_011276341.1 - 9.5e-14 50.8 2.8 9.5e-14 50.8 2.0 2.7 2 1 1 3 3 3 1 SNARE domain Syntaxin_2 PF14523.1 XP_011276341.1 - 6.9e-12 45.3 8.2 6.9e-12 45.3 5.7 2.8 2 1 0 2 2 2 1 Syntaxin-like protein Synaptobrevin PF00957.16 XP_011276341.1 - 0.00011 21.7 1.9 0.00033 20.1 1.3 1.9 1 0 0 1 1 1 1 Synaptobrevin MCPsignal PF00015.16 XP_011276341.1 - 0.00049 19.7 10.7 0.00064 19.3 2.6 2.4 2 1 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain TrbL PF04610.9 XP_011276341.1 - 0.00054 19.7 0.1 0.00083 19.1 0.0 1.2 1 0 0 1 1 1 1 TrbL/VirB6 plasmid conjugal transfer protein DUF2077 PF09850.4 XP_011276341.1 - 0.0089 15.4 0.2 0.045 13.1 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2077) DUF3899 PF13038.1 XP_011276341.1 - 0.013 15.6 0.7 0.63 10.2 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) DUF3753 PF12575.3 XP_011276341.1 - 0.035 13.9 1.1 0.098 12.4 0.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) DUF912 PF06024.7 XP_011276341.1 - 0.063 13.3 0.8 0.063 13.3 0.5 2.7 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) ODV-E18 PF10717.4 XP_011276341.1 - 0.22 11.0 1.4 0.24 10.8 0.1 1.8 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Pex14_N PF04695.8 XP_011276341.1 - 1.1 9.2 7.5 5.2 7.1 0.0 2.3 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region OppC_N PF12911.2 XP_011276341.1 - 1.3 8.4 3.7 2.5 7.5 2.6 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C DUF2116 PF09889.4 XP_011276341.1 - 1.9 8.3 3.8 1.3 8.8 0.7 2.1 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) T2SF PF00482.18 XP_011276341.1 - 5.5 6.9 9.4 8.8 6.2 4.4 2.7 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein F DNA_pol_B PF00136.16 XP_011276342.1 - 4.9e-114 381.6 2.9 7.9e-114 380.9 2.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.5 XP_011276342.1 - 1.3e-61 207.2 10.4 2.5e-61 206.3 7.2 1.5 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 XP_011276342.1 - 3.7e-35 121.3 0.0 1.3e-34 119.5 0.0 1.9 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 XP_011276342.1 - 5.9e-20 70.8 6.7 1.8e-19 69.3 4.6 1.9 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal Corona_S2 PF01601.11 XP_011276343.1 - 9.9 4.1 7.5 13 3.7 5.2 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein ApoO PF09769.4 XP_011276344.1 - 9.2e-31 106.6 0.0 1.5e-30 106.0 0.0 1.3 1 0 0 1 1 1 1 Apolipoprotein O DUF2963 PF11178.3 XP_011276344.1 - 0.54 9.7 4.3 4.3 6.8 3.0 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2963) Mito_carr PF00153.22 XP_011276345.1 - 5.9e-60 199.0 7.2 2.7e-20 71.8 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_M14 PF00246.19 XP_011276346.1 - 9.5e-66 222.2 0.0 1.8e-65 221.3 0.0 1.4 1 0 0 1 1 1 1 Zinc carboxypeptidase Prefoldin_2 PF01920.15 XP_011276347.1 - 1.2e-16 60.3 12.8 1.2e-16 60.3 8.9 1.4 2 0 0 2 2 2 1 Prefoldin subunit MtrG PF04210.8 XP_011276347.1 - 0.018 14.6 0.0 0.049 13.3 0.0 1.7 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G AAA_23 PF13476.1 XP_011276347.1 - 5.2 7.3 17.0 6.8 6.9 11.8 1.1 1 0 0 1 1 1 0 AAA domain Seryl_tRNA_N PF02403.17 XP_011276347.1 - 5.3 7.0 16.9 1.6 8.8 1.3 2.2 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain A_deaminase PF00962.17 XP_011276348.1 - 3.2e-80 269.5 0.0 3.7e-80 269.3 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Aminotran_1_2 PF00155.16 XP_011276349.1 - 1.2e-15 57.3 0.0 1.6e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 XP_011276349.1 - 0.12 10.9 0.0 0.43 9.0 0.0 1.7 1 1 0 1 1 1 0 Alanine-glyoxylate amino-transferase DUF1741 PF08427.5 XP_011276351.1 - 0.056 12.8 2.0 0.058 12.8 1.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1741) CASP_C PF08172.7 XP_011276351.1 - 0.77 8.7 5.5 0.92 8.4 3.8 1.1 1 0 0 1 1 1 0 CASP C terminal Band_7 PF01145.20 XP_011276353.1 - 1.5e-25 90.1 4.2 2.2e-25 89.5 2.6 1.5 1 1 0 1 1 1 1 SPFH domain / Band 7 family DUF2884 PF11101.3 XP_011276353.1 - 0.034 13.5 1.1 0.052 12.9 0.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2884) Pet20 PF08692.5 XP_011276354.1 - 1.8e-07 31.1 2.3 2.9e-06 27.2 0.2 2.7 1 1 2 3 3 3 2 Mitochondrial protein Pet20 IL6 PF00489.12 XP_011276354.1 - 0.28 10.7 1.7 0.55 9.8 0.5 1.9 2 0 0 2 2 2 0 Interleukin-6/G-CSF/MGF family DUF3439 PF11921.3 XP_011276354.1 - 0.76 9.5 9.2 1.2 8.8 6.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Phage_connect_1 PF05135.8 XP_011276355.1 - 0.53 10.4 5.4 4.6 7.4 0.1 3.9 4 0 0 4 4 4 0 Phage gp6-like head-tail connector protein RTA1 PF04479.8 XP_011276356.1 - 3.2e-44 151.0 14.6 1.7e-25 89.8 2.1 2.2 1 1 1 2 2 2 2 RTA1 like protein zf-DHHC PF01529.15 XP_011276356.1 - 0.011 15.0 0.9 0.011 15.0 0.6 2.9 2 1 0 2 2 2 0 DHHC palmitoyltransferase RTA1 PF04479.8 XP_011276357.1 - 2.4e-64 216.9 20.6 3.5e-64 216.3 14.3 1.2 1 0 0 1 1 1 1 RTA1 like protein CBM_21 PF03370.8 XP_011276358.1 - 9.6e-32 109.3 4.4 9.6e-32 109.3 3.0 3.2 4 1 1 5 5 5 1 Putative phosphatase regulatory subunit WD40 PF00400.27 XP_011276359.1 - 7.5e-57 187.3 26.4 1.5e-10 40.5 0.2 8.3 8 0 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.3 XP_011276359.1 - 5.5e-17 61.1 4.2 0.00032 18.9 0.0 6.1 3 1 3 6 6 6 5 Nucleoporin Nup120/160 F-box-like PF12937.2 XP_011276359.1 - 3.4e-13 49.0 0.6 6.7e-13 48.1 0.4 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 XP_011276359.1 - 3.1e-10 39.4 0.5 6.3e-10 38.4 0.3 1.6 1 0 0 1 1 1 1 F-box domain SR-25 PF10500.4 XP_011276359.1 - 0.00054 19.5 2.2 0.00054 19.5 1.5 1.5 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein PRANC PF09372.5 XP_011276359.1 - 0.0096 15.8 0.1 0.03 14.2 0.1 1.9 1 0 0 1 1 1 1 PRANC domain PQQ_2 PF13360.1 XP_011276359.1 - 0.064 12.7 0.0 0.28 10.5 0.0 2.1 2 1 0 2 2 2 0 PQQ-like domain ATP11 PF06644.6 XP_011276359.1 - 0.21 11.0 2.2 0.37 10.2 1.5 1.3 1 0 0 1 1 1 0 ATP11 protein Peptidase_C48 PF02902.14 XP_011276360.1 - 1.8e-16 60.4 0.1 1.8e-16 60.4 0.1 2.6 2 1 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain Ribosomal_S24e PF01282.14 XP_011276360.1 - 0.2 11.4 4.9 7.9 6.3 0.8 2.5 2 0 0 2 2 2 0 Ribosomal protein S24e adh_short PF00106.20 XP_011276361.1 - 4.1e-25 88.6 0.0 5.1e-25 88.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 XP_011276361.1 - 8.5e-20 71.5 1.2 1.1e-19 71.1 0.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 XP_011276361.1 - 2e-08 34.1 0.0 2.7e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 XP_011276361.1 - 0.093 12.7 0.3 0.71 9.8 0.2 2.2 1 1 0 1 1 1 0 NADH(P)-binding Sugar_tr PF00083.19 XP_011276362.1 - 5.1e-86 289.0 20.1 6e-86 288.7 14.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 XP_011276362.1 - 4.1e-21 75.0 11.3 4.1e-21 75.0 7.9 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Col_cuticle_N PF01484.12 XP_011276362.1 - 1.5 8.5 5.9 0.29 10.8 0.1 2.8 3 0 0 3 3 3 0 Nematode cuticle collagen N-terminal domain HisG PF01634.13 XP_011276363.1 - 2.1e-52 176.9 0.0 2.9e-52 176.5 0.0 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 XP_011276363.1 - 9.7e-28 95.9 0.0 1.8e-27 95.0 0.0 1.4 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.6 XP_011276363.1 - 0.13 11.8 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 NMT1/THI5 like Ribosomal_S28e PF01200.13 XP_011276364.1 - 8.6e-33 111.9 3.0 9.3e-33 111.7 2.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Cyclin PF08613.6 XP_011276365.1 - 6.3e-40 137.0 0.9 6.3e-40 137.0 0.6 3.5 2 2 0 2 2 2 1 Cyclin SMAP PF15477.1 XP_011276366.1 - 3.7 7.8 5.6 6 7.2 3.9 1.5 1 1 0 1 1 1 0 Small acidic protein family Ribosomal_L34e PF01199.13 XP_011276367.1 - 1.5e-32 111.6 1.2 3.5e-32 110.4 0.9 1.6 1 0 0 1 1 1 1 Ribosomal protein L34e Ribonuc_L-PSP PF01042.16 XP_011276367.1 - 1.9e-29 101.8 0.1 3.6e-29 100.9 0.0 1.4 1 0 0 1 1 1 1 Endoribonuclease L-PSP E1-E2_ATPase PF00122.15 XP_011276368.1 - 1.5e-24 86.3 0.1 4.1e-24 84.8 0.1 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 XP_011276368.1 - 8.9e-13 49.1 0.0 2.8e-12 47.5 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 XP_011276368.1 - 1.1e-10 42.0 0.5 2.9e-10 40.6 0.4 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 XP_011276368.1 - 1.9e-07 30.9 0.0 7.4e-07 29.0 0.0 2.0 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 XP_011276368.1 - 0.0012 18.5 0.1 0.0012 18.5 0.1 2.6 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase EXS PF03124.9 XP_011276369.1 - 3.6e-88 295.8 29.7 1e-75 254.9 10.7 2.1 1 1 1 2 2 2 2 EXS family SPX PF03105.14 XP_011276369.1 - 1.8e-34 119.8 20.9 1.8e-34 119.8 14.5 1.8 2 1 0 2 2 2 1 SPX domain DUF4131 PF13567.1 XP_011276369.1 - 8.9 5.6 8.8 2.3 7.6 3.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) ketoacyl-synt PF00109.21 XP_011276370.1 - 1.3e-59 201.7 0.0 1.6e-59 201.4 0.0 1.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 XP_011276370.1 - 1.3e-31 108.8 0.2 2.7e-31 107.8 0.0 1.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Steroid_dh PF02544.11 XP_011276371.1 - 1.8e-10 40.8 6.2 5.1e-10 39.3 4.1 2.0 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase MFS_1 PF07690.11 XP_011276372.1 - 6.2e-37 127.1 16.9 9.9e-37 126.4 11.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily FKBP_C PF00254.23 XP_011276373.1 - 1.7e-31 108.0 0.0 2.2e-31 107.7 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF4220 PF13968.1 XP_011276373.1 - 0.13 11.2 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) TPR_11 PF13414.1 XP_011276374.1 - 1.1e-06 28.2 0.6 0.023 14.3 0.0 2.9 2 1 0 2 2 2 2 TPR repeat TPR_12 PF13424.1 XP_011276374.1 - 1.9e-06 27.7 0.0 0.0023 17.8 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 XP_011276374.1 - 0.00025 20.7 0.1 1.2 9.2 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 XP_011276374.1 - 0.00034 20.6 0.3 0.0028 17.7 0.1 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 XP_011276374.1 - 0.0038 17.5 0.1 0.2 12.0 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 XP_011276374.1 - 0.011 15.3 0.1 2.4 7.8 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 XP_011276374.1 - 0.011 15.4 2.9 0.028 14.2 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 XP_011276374.1 - 0.012 15.8 0.1 15 6.1 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 XP_011276374.1 - 0.022 14.5 0.2 14 5.8 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 XP_011276374.1 - 0.059 14.0 0.0 1.7 9.4 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat SH3_1 PF00018.23 XP_011276375.1 - 1.5e-11 43.4 3.0 2.8e-11 42.6 0.0 2.7 3 0 0 3 3 3 1 SH3 domain SH3_9 PF14604.1 XP_011276375.1 - 6.3e-11 41.6 0.1 6.3e-11 41.6 0.1 2.6 3 0 0 3 3 3 1 Variant SH3 domain SH3_2 PF07653.12 XP_011276375.1 - 5.1e-07 29.0 0.0 9.1e-07 28.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Cwf_Cwc_15 PF04889.7 XP_011276376.1 - 1.5e-47 162.3 29.0 2e-47 161.9 20.1 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DWNN PF08783.6 XP_011276376.1 - 0.53 10.2 6.5 0.061 13.2 0.8 2.3 2 0 0 2 2 2 0 DWNN domain CDC45 PF02724.9 XP_011276376.1 - 0.57 8.1 19.8 0.64 7.9 13.8 1.2 1 0 0 1 1 1 0 CDC45-like protein DALR_1 PF05746.10 XP_011276376.1 - 3 7.8 7.1 0.48 10.4 2.1 1.8 2 0 0 2 2 2 0 DALR anticodon binding domain SprA-related PF12118.3 XP_011276376.1 - 9.2 5.4 15.4 14 4.8 10.7 1.3 1 0 0 1 1 1 0 SprA-related family Mito_carr PF00153.22 XP_011276377.1 - 9.9e-63 207.8 2.9 4.2e-23 80.8 0.4 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Nbl1_Borealin_N PF10444.4 XP_011276378.1 - 0.00014 21.1 3.6 0.00014 21.1 2.5 2.3 2 0 0 2 2 2 2 Nbl1 / Borealin N terminal V-ATPase_G PF03179.10 XP_011276378.1 - 0.46 10.7 12.3 0.065 13.5 2.8 2.2 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit OmpH PF03938.9 XP_011276378.1 - 5.7 6.8 18.7 0.025 14.5 3.9 2.0 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Mito_carr PF00153.22 XP_011276379.1 - 1.3e-65 217.0 0.0 9.5e-22 76.5 0.2 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein adh_short PF00106.20 XP_011276380.1 - 6.5e-19 68.4 0.0 9.3e-19 67.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 XP_011276380.1 - 4e-10 39.8 0.1 5.7e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 XP_011276380.1 - 0.00078 19.4 0.0 0.0015 18.5 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 XP_011276380.1 - 0.0026 17.4 0.0 0.007 16.0 0.0 1.8 1 1 0 1 1 1 1 KR domain MUG2_C PF08593.5 XP_011276380.1 - 0.011 15.9 1.1 0.061 13.5 0.5 2.3 2 0 0 2 2 2 0 Meiotically up-regulated glycoproteins C-terminal Shikimate_DH PF01488.15 XP_011276380.1 - 0.084 12.9 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 XP_011276380.1 - 0.13 11.9 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AAA PF00004.24 XP_011276382.1 - 2.3e-10 40.7 0.1 6.8e-10 39.2 0.1 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 XP_011276382.1 - 5.9e-09 36.1 0.1 1.4e-08 34.9 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 XP_011276382.1 - 3.4e-06 27.1 0.0 1.4e-05 25.1 0.0 1.9 1 1 1 2 2 2 1 AAA ATPase domain NTPase_1 PF03266.10 XP_011276382.1 - 0.0035 17.0 0.1 0.015 15.0 0.0 2.1 2 0 0 2 2 2 1 NTPase DUF2075 PF09848.4 XP_011276382.1 - 0.0041 16.1 0.0 0.0092 14.9 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Arch_ATPase PF01637.13 XP_011276382.1 - 0.005 16.5 3.6 0.0063 16.2 0.1 2.5 2 1 0 2 2 2 1 Archaeal ATPase AAA_19 PF13245.1 XP_011276382.1 - 0.0079 15.9 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 XP_011276382.1 - 0.054 13.2 0.1 0.28 10.9 0.0 2.3 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AFG1_ATPase PF03969.11 XP_011276382.1 - 0.064 12.0 0.0 0.22 10.2 0.0 1.8 2 0 0 2 2 2 0 AFG1-like ATPase Fanconi_A PF03511.9 XP_011276382.1 - 0.08 12.7 0.0 0.29 10.9 0.0 1.9 1 0 0 1 1 1 0 Fanconi anaemia group A protein NACHT PF05729.7 XP_011276382.1 - 0.14 11.8 6.3 0.13 11.9 1.9 2.5 2 1 0 2 2 2 0 NACHT domain Pkinase PF00069.20 XP_011276383.1 - 2.3e-71 240.0 0.0 2.6e-71 239.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011276383.1 - 1.6e-30 106.0 0.0 2.1e-30 105.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 XP_011276383.1 - 0.00051 19.0 0.0 0.00081 18.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 XP_011276383.1 - 0.021 14.5 0.0 0.041 13.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 XP_011276383.1 - 0.084 11.6 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 ThiF PF00899.16 XP_011276384.1 - 5.2e-35 120.2 0.0 8.3e-35 119.5 0.0 1.3 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 XP_011276384.1 - 0.012 15.6 0.1 0.026 14.6 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 XP_011276384.1 - 0.017 15.1 0.3 0.1 12.5 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain 3HCDH_N PF02737.13 XP_011276384.1 - 0.023 14.3 0.4 0.13 11.9 0.0 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 XP_011276384.1 - 0.028 13.7 0.6 0.21 10.9 0.0 2.3 1 1 1 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.22 XP_011276384.1 - 0.047 14.0 1.1 2.2 8.7 0.1 3.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 XP_011276384.1 - 0.078 12.0 0.1 0.13 11.2 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.19 XP_011276384.1 - 0.087 11.7 4.2 0.11 11.3 0.2 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.18 XP_011276384.1 - 0.11 12.2 0.1 0.54 9.9 0.0 2.0 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 XP_011276384.1 - 0.13 11.7 0.1 0.38 10.1 0.0 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA GTP_EFTU PF00009.22 XP_011276385.1 - 1.2e-48 165.1 0.0 1.8e-48 164.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 XP_011276385.1 - 8.9e-38 128.5 5.4 1.9e-37 127.4 3.7 1.6 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 XP_011276385.1 - 1.5e-18 66.3 0.0 2.9e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus Ras PF00071.17 XP_011276385.1 - 4.1e-07 29.5 0.0 9.6e-07 28.3 0.0 1.6 1 0 0 1 1 1 1 Ras family GTP_EFTU_D2 PF03144.20 XP_011276385.1 - 1.7e-05 24.8 1.1 2.8e-05 24.1 0.1 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 SRPRB PF09439.5 XP_011276385.1 - 0.00044 19.5 0.1 0.0013 17.9 0.0 1.8 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit EFG_II PF14492.1 XP_011276385.1 - 0.00062 19.5 0.0 0.0027 17.5 0.0 2.2 2 0 0 2 2 2 1 Elongation Factor G, domain II Miro PF08477.8 XP_011276385.1 - 0.059 13.8 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein Aminotran_5 PF00266.14 XP_011276386.1 - 2.6e-35 121.8 0.0 3e-35 121.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Mei5 PF10376.4 XP_011276386.1 - 0.071 12.6 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Double-strand recombination repair protein Hus1 PF04005.7 XP_011276387.1 - 4.4e-54 183.4 4.4 5.1e-54 183.2 3.0 1.0 1 0 0 1 1 1 1 Hus1-like protein Rad1 PF02144.11 XP_011276387.1 - 0.00018 20.3 0.3 0.00033 19.5 0.2 1.5 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 IF-2B PF01008.12 XP_011276388.1 - 9.6e-76 254.4 0.5 1.2e-75 254.1 0.3 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Flocculin_t3 PF13928.1 XP_011276389.1 - 2.3e-16 59.6 71.6 2.1e-10 40.5 14.3 5.9 7 0 0 7 7 7 3 Flocculin type 3 repeat Collagen PF01391.13 XP_011276389.1 - 1.5 8.4 9.2 3 7.4 6.4 1.5 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Hid1 PF12722.2 XP_011276389.1 - 6.1 4.3 17.0 8.5 3.9 11.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MFS_1 PF07690.11 XP_011276390.1 - 4.5e-33 114.4 23.6 3.2e-31 108.3 15.4 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily CbtB PF09489.5 XP_011276390.1 - 0.066 13.1 3.6 2.8 7.8 0.1 2.9 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) CTC1 PF15489.1 XP_011276390.1 - 0.16 9.2 0.0 0.21 8.8 0.0 1.2 1 0 0 1 1 1 0 CST, telomere maintenance, complex subunit CTC1 Telomere_Sde2 PF13019.1 XP_011276391.1 - 2.3e-22 79.4 0.1 3.6e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 Telomere stability and silencing Med11 PF10280.4 XP_011276391.1 - 0.0026 17.7 1.5 0.0054 16.7 1.0 1.5 1 0 0 1 1 1 1 Mediator complex protein KNOX2 PF03791.8 XP_011276391.1 - 0.033 13.4 0.1 0.19 11.0 0.1 2.1 2 0 0 2 2 2 0 KNOX2 domain Astro_capsid PF03115.9 XP_011276391.1 - 4.8 5.3 10.3 6 4.9 7.1 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor DUF2146 PF10220.4 XP_011276391.1 - 4.9 4.9 11.8 6.2 4.6 8.2 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) GTP_EFTU PF00009.22 XP_011276392.1 - 4.2e-20 71.9 0.1 4.9e-20 71.7 0.1 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MobB PF03205.9 XP_011276392.1 - 0.057 13.1 0.0 0.087 12.5 0.0 1.2 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 XP_011276392.1 - 0.06 13.3 0.0 0.083 12.8 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.22 XP_011276392.1 - 0.11 12.7 0.0 0.14 12.4 0.0 1.1 1 0 0 1 1 1 0 ABC transporter GTP_EFTU_D3 PF03143.12 XP_011276393.1 - 4.6e-26 90.8 0.1 1.8e-25 88.9 0.0 2.1 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain GTP_EFTU PF00009.22 XP_011276393.1 - 4.9e-26 91.3 0.1 7.4e-26 90.7 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.20 XP_011276393.1 - 3.9e-23 81.3 2.2 1e-22 80.0 1.5 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 XP_011276393.1 - 0.00016 21.2 0.6 0.00038 20.0 0.4 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 4 G_glu_transpept PF01019.16 XP_011276394.1 - 1.1e-140 469.4 0.0 1.4e-140 469.1 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Tubulin_C PF03953.12 XP_011276395.1 - 7.7e-49 164.9 0.0 1.3e-48 164.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.20 XP_011276395.1 - 1.1e-30 107.1 0.0 1.6e-30 106.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Elongin_A PF06881.6 XP_011276396.1 - 0.024 14.9 0.4 0.073 13.4 0.3 1.8 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A ALO PF04030.9 XP_011276397.1 - 4.8e-99 331.1 0.4 6.5e-99 330.7 0.3 1.2 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 XP_011276397.1 - 4.8e-28 97.3 0.1 7.3e-28 96.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 XP_011276397.1 - 0.014 15.3 0.1 0.036 13.9 0.1 1.7 1 0 0 1 1 1 0 Berberine and berberine like NAD_binding_1 PF00175.16 XP_011276398.1 - 1.6e-24 86.5 0.0 2.5e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 XP_011276398.1 - 9.8e-24 83.3 0.0 1.7e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 XP_011276398.1 - 3.3e-05 23.8 0.0 0.00038 20.3 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Exo_endo_phos PF03372.18 XP_011276399.1 - 4.8e-18 66.0 0.0 6.8e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DTHCT PF08070.6 XP_011276399.1 - 0.077 13.6 3.1 0.16 12.6 2.1 1.6 1 0 0 1 1 1 0 DTHCT (NUC029) region MFS_1 PF07690.11 XP_011276400.1 - 3.5e-37 127.9 51.9 1.9e-28 99.2 19.4 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 XP_011276400.1 - 5.4e-16 58.2 12.0 5.4e-16 58.2 8.3 2.9 3 1 0 3 3 3 1 Sugar (and other) transporter RhodobacterPufX PF11511.3 XP_011276400.1 - 0.44 9.9 0.0 0.44 9.9 0.0 2.4 3 0 0 3 3 3 0 Intrinsic membrane protein PufX Tubulin PF00091.20 XP_011276401.1 - 5.1e-59 199.6 0.0 9.1e-59 198.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 XP_011276401.1 - 1.1e-48 164.3 0.0 2e-48 163.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 XP_011276401.1 - 0.0022 17.4 0.0 0.0042 16.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Rsc14 PF08586.5 XP_011276401.1 - 0.078 13.4 0.5 0.36 11.3 0.0 2.3 3 0 0 3 3 3 0 RSC complex, Rsc14/Ldb7 subunit Ion_trans_N PF08412.5 XP_011276402.1 - 1 8.7 6.5 2.2 7.6 1.1 2.5 2 0 0 2 2 2 0 Ion transport protein N-terminal Ras PF00071.17 XP_011276403.1 - 1.6e-64 216.2 0.4 1.9e-64 215.9 0.3 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 XP_011276403.1 - 7.6e-21 74.8 0.0 1.1e-20 74.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 XP_011276403.1 - 3e-17 62.4 0.2 3.6e-17 62.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 XP_011276403.1 - 7.4e-08 31.8 0.1 8.7e-08 31.5 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 XP_011276403.1 - 1.4e-05 24.9 0.1 2.5e-05 24.2 0.1 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 XP_011276403.1 - 8.6e-05 22.0 0.1 0.00018 21.0 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 XP_011276403.1 - 0.00032 19.9 0.0 0.0005 19.3 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 XP_011276403.1 - 0.0012 19.0 0.0 0.0021 18.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 XP_011276403.1 - 0.0045 17.1 0.0 0.038 14.1 0.0 2.1 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.13 XP_011276403.1 - 0.0059 15.8 0.0 0.043 13.1 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.1 XP_011276403.1 - 0.018 15.0 0.1 0.06 13.3 0.0 1.9 2 1 0 2 2 2 0 AAA ATPase domain PduV-EutP PF10662.4 XP_011276403.1 - 0.021 14.3 0.1 0.79 9.2 0.0 2.3 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 XP_011276403.1 - 0.022 13.9 0.0 0.059 12.5 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 XP_011276403.1 - 0.027 14.0 0.0 0.11 12.0 0.0 2.0 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 XP_011276403.1 - 0.077 13.2 0.6 0.15 12.3 0.4 1.7 1 1 0 1 1 1 0 ABC transporter AAA_5 PF07728.9 XP_011276403.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF788 PF05620.6 XP_011276404.1 - 2e-46 157.9 0.4 2.2e-46 157.8 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) YwiC PF14256.1 XP_011276404.1 - 0.041 13.9 1.5 0.16 12.0 0.1 2.0 2 0 0 2 2 2 0 YwiC-like protein Peroxin-13_N PF04088.8 XP_011276404.1 - 0.1 12.5 0.4 3.4 7.6 0.1 2.3 2 1 0 2 2 2 0 Peroxin 13, N-terminal region bZIP_1 PF00170.16 XP_011276405.1 - 9.2e-09 35.1 3.2 2.7e-08 33.6 2.2 1.8 1 0 0 1 1 1 1 bZIP transcription factor Aft1_OSA PF11785.3 XP_011276405.1 - 8e-06 26.2 2.2 8e-06 26.2 1.5 5.4 6 1 1 7 7 7 1 Aft1 osmotic stress response (OSM) domain bZIP_2 PF07716.10 XP_011276405.1 - 5.3e-05 22.9 4.1 5.3e-05 22.9 2.9 3.6 4 0 0 4 4 4 1 Basic region leucine zipper Aft1_HRA PF11786.3 XP_011276405.1 - 0.045 14.0 9.9 0.16 12.2 6.4 2.4 1 1 0 1 1 1 0 Aft1 HRA domain Med15 PF09606.5 XP_011276405.1 - 3.3 5.7 93.5 0.073 11.2 16.1 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Baculo_PEP_C PF04513.7 XP_011276406.1 - 0.018 14.8 17.1 0.12 12.2 4.2 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.7 XP_011276406.1 - 0.11 12.7 4.9 1.3 9.3 0.3 3.0 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF2336 PF10098.4 XP_011276407.1 - 0.058 12.6 0.1 0.067 12.4 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2336) FANCI_S2 PF14676.1 XP_011276407.1 - 0.06 13.2 0.0 0.074 12.9 0.0 1.2 1 0 0 1 1 1 0 FANCI solenoid 2 SecD_SecF PF02355.11 XP_011276407.1 - 0.062 12.4 0.3 0.11 11.7 0.2 1.4 1 0 0 1 1 1 0 Protein export membrane protein CENP-Q PF13094.1 XP_011276407.1 - 0.075 13.0 0.5 0.1 12.6 0.4 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit OSCP PF00213.13 XP_011276407.1 - 0.25 11.1 2.5 2.1 8.1 1.6 2.0 1 1 1 2 2 2 0 ATP synthase delta (OSCP) subunit MF_alpha_N PF05436.6 XP_011276407.1 - 0.28 10.8 2.2 0.28 10.8 0.3 1.9 2 1 0 2 2 2 0 Mating factor alpha precursor N-terminus Baculo_PEP_C PF04513.7 XP_011276408.1 - 0.015 15.1 13.9 0.049 13.4 9.5 2.0 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.7 XP_011276408.1 - 0.039 14.1 3.6 0.78 10.0 0.7 2.8 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Yos1 PF08571.5 XP_011276408.1 - 0.11 12.5 0.4 0.11 12.5 0.3 1.8 2 0 0 2 2 2 0 Yos1-like TrbL PF04610.9 XP_011276408.1 - 0.19 11.4 2.5 0.4 10.3 0.7 2.0 1 1 2 3 3 3 0 TrbL/VirB6 plasmid conjugal transfer protein FAA_hydrolase PF01557.13 XP_011276409.1 - 1.7e-51 174.7 0.0 2.1e-51 174.4 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family PS_Dcarbxylase PF02666.10 XP_011276410.1 - 4.7e-79 264.3 0.2 2e-77 259.0 0.1 2.1 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase dCMP_cyt_deam_1 PF00383.17 XP_011276411.1 - 1.2e-23 82.6 1.1 1.7e-23 82.1 0.8 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region AAA_18 PF13238.1 XP_011276411.1 - 5e-09 36.5 0.0 8.3e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 XP_011276411.1 - 5.5e-05 23.9 0.0 0.0001 23.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain CoaE PF01121.15 XP_011276411.1 - 0.0038 16.6 0.0 0.0081 15.5 0.0 1.6 1 1 0 1 1 1 1 Dephospho-CoA kinase Apc1 PF12859.2 XP_011276412.1 - 3.4e-08 33.6 7.6 5.2e-08 33.0 2.1 3.3 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 XP_011276412.1 - 0.55 10.5 8.3 0.36 11.1 0.1 3.6 3 0 0 3 3 3 0 Proteasome/cyclosome repeat Flocculin_t3 PF13928.1 XP_011276413.1 - 1.4e-12 47.5 23.1 1.4e-12 47.5 16.0 7.8 6 2 0 6 6 6 2 Flocculin type 3 repeat Aldo_ket_red PF00248.16 XP_011276414.1 - 7.3e-44 149.6 0.0 9.2e-44 149.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family MF_alpha_N PF05436.6 XP_011276415.1 - 0.14 11.8 1.0 0.17 11.6 0.7 1.3 1 1 0 1 1 1 0 Mating factor alpha precursor N-terminus Flocculin_t3 PF13928.1 XP_011276416.1 - 6.9e-10 38.9 60.5 9.7e-08 32.0 16.2 4.7 3 1 1 4 4 4 3 Flocculin type 3 repeat FLYWCH PF04500.11 XP_011276416.1 - 0.087 12.7 0.2 18 5.2 0.0 2.7 2 0 0 2 2 2 0 FLYWCH zinc finger domain Aldo_ket_red PF00248.16 XP_011276417.1 - 1.5e-47 161.7 0.0 2e-47 161.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RTP PF02334.11 XP_011276417.1 - 0.05 13.5 0.1 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Replication terminator protein Fungal_trans PF04082.13 XP_011276418.1 - 5e-18 64.9 7.9 5e-18 64.9 5.5 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 XP_011276418.1 - 7.9e-07 28.8 9.7 1.8e-06 27.7 6.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1640 PF07798.6 XP_011276419.1 - 3.1e-08 33.8 8.2 5.6e-08 33.0 5.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) FAM176 PF14851.1 XP_011276419.1 - 7.3 6.2 7.2 2.5 7.7 0.7 2.5 3 0 0 3 3 3 0 FAM176 family ECH PF00378.15 XP_011276420.1 - 1.6e-19 70.0 0.0 2.8e-19 69.1 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Stk19 PF10494.4 XP_011276422.1 - 1.2e-30 106.7 3.3 1.5e-30 106.4 2.3 1.0 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 Aldo_ket_red PF00248.16 XP_011276423.1 - 2.9e-39 134.5 0.0 3.9e-39 134.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF1682 PF07946.9 XP_011276424.1 - 1.1e-88 297.1 7.6 1.3e-88 296.9 5.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Mitofilin PF09731.4 XP_011276424.1 - 0.075 11.6 16.6 0.1 11.2 11.5 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Bul1_N PF04425.7 XP_011276425.1 - 6.4e-108 361.1 8.4 6.4e-108 361.1 5.8 2.0 3 0 0 3 3 3 1 Bul1 N terminus Bul1_C PF04426.7 XP_011276425.1 - 4.3e-24 85.1 20.2 1.3e-16 60.6 2.2 3.3 2 1 0 3 3 3 2 Bul1 C terminus PPI_Ypi1 PF07491.6 XP_011276426.1 - 3.3e-05 23.4 19.6 3.3e-05 23.4 13.6 3.6 2 1 1 3 3 3 1 Protein phosphatase inhibitor SR-25 PF10500.4 XP_011276426.1 - 0.21 11.0 36.2 0.67 9.3 25.1 1.8 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein YL1 PF05764.8 XP_011276426.1 - 0.29 10.7 23.0 0.37 10.3 15.9 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Nic96 PF04097.9 XP_011276427.1 - 2.7e-184 613.7 7.9 3.7e-184 613.3 5.5 1.2 1 0 0 1 1 1 1 Nup93/Nic96 Helicase_C_2 PF13307.1 XP_011276428.1 - 2.4e-51 174.0 0.5 2.1e-50 170.9 0.0 2.3 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.10 XP_011276428.1 - 4.6e-48 162.9 1.0 8.9e-48 161.9 0.7 1.5 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.10 XP_011276428.1 - 0.00017 21.4 7.1 0.11 12.3 0.0 3.5 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit DEAD PF00270.24 XP_011276428.1 - 0.01 15.3 0.0 4 6.9 0.0 2.6 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_22 PF13401.1 XP_011276428.1 - 0.18 11.9 0.8 6.1 6.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 XP_011276428.1 - 0.26 11.5 4.5 1.4 9.2 3.1 2.2 1 1 0 1 1 1 0 ABC transporter zf-TFIIIC PF12660.2 XP_011276430.1 - 2.8e-09 36.7 0.0 5.3e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex TFIIIC_delta PF12657.2 XP_011276430.1 - 7.1e-07 29.0 0.1 2e-06 27.6 0.1 1.7 1 0 0 1 1 1 1 Transcription factor IIIC subunit delta N-term Patched PF02460.13 XP_011276431.1 - 2.6e-69 234.0 28.4 4.2e-68 230.0 19.7 2.2 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.3 XP_011276431.1 - 1.9e-43 147.5 3.2 1.9e-43 147.5 2.2 2.7 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.14 XP_011276431.1 - 0.0078 13.6 20.0 0.004 14.6 10.2 2.1 2 0 0 2 2 2 2 AcrB/AcrD/AcrF family MMPL PF03176.10 XP_011276431.1 - 2.3 6.8 20.6 0.36 9.4 0.1 2.4 2 0 0 2 2 2 0 MMPL family PPR_2 PF13041.1 XP_011276432.1 - 1.2e-09 38.0 4.1 0.00042 20.2 0.1 4.1 3 1 1 4 4 4 3 PPR repeat family PPR_1 PF12854.2 XP_011276432.1 - 0.062 12.7 0.5 3.9 7.0 0.0 3.0 3 0 0 3 3 3 0 PPR repeat Glyco_hydro_18 PF00704.23 XP_011276433.1 - 9.3e-24 84.5 3.9 8.2e-21 74.8 0.8 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 CBM_19 PF03427.8 XP_011276434.1 - 7.4e-07 28.8 7.6 7.4e-07 28.8 5.3 4.9 3 2 4 7 7 7 1 Carbohydrate binding domain (family 19) TFIIA PF03153.8 XP_011276434.1 - 8 6.2 23.9 11 5.7 16.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Methyltransf_16 PF10294.4 XP_011276435.1 - 3.8e-19 68.7 0.0 5.5e-19 68.2 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 XP_011276435.1 - 1.9e-05 24.4 0.1 6e-05 22.8 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 XP_011276435.1 - 0.0034 17.8 0.0 0.0089 16.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 XP_011276435.1 - 0.0052 16.3 0.2 0.008 15.7 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 XP_011276435.1 - 0.0068 16.9 0.0 0.012 16.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 XP_011276435.1 - 0.0096 16.3 0.0 0.015 15.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain ImmE5 PF11480.3 XP_011276436.1 - 0.22 11.3 1.0 0.32 10.8 0.7 1.4 1 0 0 1 1 1 0 Colicin-E5 Imm protein DUF2366 PF10171.4 XP_011276437.1 - 0.01 15.3 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2366) Mannosyl_trans3 PF11051.3 XP_011276438.1 - 1.8e-58 198.0 0.8 3.5e-58 197.1 0.6 1.5 1 0 0 1 1 1 1 Mannosyltransferase putative Glyco_transf_8 PF01501.15 XP_011276438.1 - 1.6e-05 24.3 0.4 1.6e-05 24.3 0.3 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 8 Dynamitin PF04912.9 XP_011276439.1 - 4.9e-21 74.9 32.6 5.4e-16 58.3 7.6 2.2 1 1 1 2 2 2 2 Dynamitin DUF1664 PF07889.7 XP_011276439.1 - 0.00024 20.9 20.2 0.0025 17.5 0.8 3.7 2 2 1 3 3 3 2 Protein of unknown function (DUF1664) BLOC1_2 PF10046.4 XP_011276439.1 - 0.0019 18.2 2.4 0.0019 18.2 1.6 4.7 1 1 5 6 6 6 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF479 PF04336.7 XP_011276439.1 - 0.005 16.9 3.8 0.4 10.8 0.1 3.4 2 2 1 3 3 3 1 Protein of unknown function, DUF479 CENP-Q PF13094.1 XP_011276439.1 - 0.04 13.9 19.5 0.16 11.9 8.2 2.4 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit PilJ PF13675.1 XP_011276439.1 - 0.13 12.5 2.6 4.3 7.7 0.1 3.3 2 1 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Reo_sigmaC PF04582.7 XP_011276439.1 - 0.21 10.6 10.1 0.32 10.1 0.6 3.0 1 1 2 3 3 3 0 Reovirus sigma C capsid protein DUF3571 PF12095.3 XP_011276439.1 - 0.72 10.1 11.3 3.5 7.9 0.8 3.9 3 1 0 3 3 3 0 Protein of unknown function (DUF3571) Laminin_II PF06009.7 XP_011276439.1 - 0.85 9.3 20.5 0.8 9.4 0.6 4.0 2 2 2 4 4 4 0 Laminin Domain II DUF4201 PF13870.1 XP_011276439.1 - 1 8.8 26.7 0.15 11.5 1.8 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4201) Rootletin PF15035.1 XP_011276439.1 - 1.3 8.9 23.9 5.2 7.0 2.1 3.3 2 1 1 3 3 3 0 Ciliary rootlet component, centrosome cohesion IncA PF04156.9 XP_011276439.1 - 2.4 7.6 29.2 4.1 6.9 4.5 3.5 2 2 1 3 3 3 0 IncA protein Snapin_Pallidin PF14712.1 XP_011276439.1 - 3.5 8.0 18.7 4.1 7.7 2.3 5.0 1 1 4 6 6 6 0 Snapin/Pallidin Syntaxin-6_N PF09177.6 XP_011276439.1 - 4 7.8 24.3 3.2 8.2 2.0 4.8 1 1 3 4 4 4 0 Syntaxin 6, N-terminal Filament PF00038.16 XP_011276439.1 - 4.6 6.6 30.2 1.2 8.5 7.8 3.0 1 1 1 2 2 1 0 Intermediate filament protein DUF2730 PF10805.3 XP_011276439.1 - 5.4 6.8 14.3 13 5.5 1.4 4.3 2 1 2 4 4 4 0 Protein of unknown function (DUF2730) NPV_P10 PF05531.7 XP_011276439.1 - 7.4 6.9 22.9 4.7 7.5 1.6 5.3 2 1 1 3 3 1 0 Nucleopolyhedrovirus P10 protein DUF2252 PF10009.4 XP_011276439.1 - 7.6 5.3 10.5 1.7 7.4 2.4 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2252) Amidase PF01425.16 XP_011276440.1 - 1.2e-110 370.4 0.2 1.5e-110 370.1 0.1 1.0 1 0 0 1 1 1 1 Amidase DUF3538 PF12057.3 XP_011276440.1 - 0.091 12.3 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3538) AAA PF00004.24 XP_011276441.1 - 2.6e-50 170.0 0.0 3.9e-42 143.5 0.0 3.1 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 XP_011276441.1 - 2.7e-07 30.7 0.4 1.8e-05 24.8 0.0 3.5 3 1 1 4 4 3 1 AAA ATPase domain IstB_IS21 PF01695.12 XP_011276441.1 - 7.7e-06 25.4 0.0 5e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.9 XP_011276441.1 - 3.4e-05 23.8 0.0 0.00014 21.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 XP_011276441.1 - 0.00011 22.4 1.8 0.013 15.6 0.1 4.1 4 1 0 4 4 3 1 AAA domain AAA_19 PF13245.1 XP_011276441.1 - 0.00037 20.1 0.0 0.019 14.7 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_5 PF07728.9 XP_011276441.1 - 0.00071 19.3 0.0 0.0031 17.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Bromodomain PF00439.20 XP_011276441.1 - 0.001 18.9 0.0 0.0036 17.1 0.0 1.9 1 0 0 1 1 1 1 Bromodomain AAA_25 PF13481.1 XP_011276441.1 - 0.0017 17.7 0.0 0.005 16.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 XP_011276441.1 - 0.0086 15.6 0.0 0.025 14.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 XP_011276441.1 - 0.01 15.8 0.0 0.56 10.2 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain RNA_helicase PF00910.17 XP_011276441.1 - 0.012 15.7 0.0 0.11 12.7 0.0 2.6 3 0 0 3 3 3 0 RNA helicase AAA_33 PF13671.1 XP_011276441.1 - 0.015 15.1 0.0 0.046 13.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 XP_011276441.1 - 0.028 13.8 0.0 1.4 8.4 0.0 2.9 3 0 0 3 3 3 0 Sigma-54 interaction domain PhoH PF02562.11 XP_011276441.1 - 0.029 13.5 0.0 0.12 11.6 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein RuvB_N PF05496.7 XP_011276441.1 - 0.043 12.8 0.0 0.085 11.8 0.0 1.5 1 1 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus KaiC PF06745.8 XP_011276441.1 - 0.048 12.7 0.0 0.14 11.2 0.0 1.8 1 0 0 1 1 1 0 KaiC Mg_chelatase PF01078.16 XP_011276441.1 - 0.055 12.6 0.2 0.13 11.3 0.1 1.6 2 0 0 2 2 1 0 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 XP_011276441.1 - 0.079 13.7 0.0 0.079 13.7 0.0 4.4 4 2 0 4 4 2 0 AAA domain AAA_18 PF13238.1 XP_011276441.1 - 0.097 12.9 0.0 0.097 12.9 0.0 4.2 4 0 0 4 4 3 0 AAA domain SRP54 PF00448.17 XP_011276442.1 - 8.2e-50 168.9 0.1 1.3e-49 168.2 0.1 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.8 XP_011276442.1 - 2.3e-21 76.3 12.6 4.6e-12 45.8 0.2 2.3 1 1 1 2 2 2 2 Signal recognition particle, alpha subunit, N-terminal SRP54_N PF02881.14 XP_011276442.1 - 2.3e-10 40.4 0.1 1e-09 38.3 0.0 2.1 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain SRX PF09201.5 XP_011276442.1 - 2.1e-07 30.7 0.0 6.9e-07 29.0 0.0 1.9 1 0 0 1 1 1 1 SRX ArgK PF03308.11 XP_011276442.1 - 1.5e-06 27.1 0.0 3.2e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 ArgK protein CbiA PF01656.18 XP_011276442.1 - 2e-06 27.3 0.1 5.9e-06 25.8 0.0 1.9 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.10 XP_011276442.1 - 0.0015 17.6 0.2 0.1 11.6 0.0 2.4 1 1 0 2 2 2 1 Anion-transporting ATPase MobB PF03205.9 XP_011276442.1 - 0.0022 17.6 0.6 0.0096 15.6 0.0 2.2 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 XP_011276442.1 - 0.0042 17.2 0.1 0.024 14.7 0.0 2.3 1 1 1 2 2 2 1 AAA domain Fer4_NifH PF00142.13 XP_011276442.1 - 0.025 13.7 0.0 0.05 12.7 0.0 1.5 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_16 PF13191.1 XP_011276442.1 - 0.026 14.5 0.0 0.083 12.8 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain NAD_binding_10 PF13460.1 XP_011276442.1 - 0.029 14.3 0.0 0.1 12.5 0.0 1.9 2 0 0 2 2 1 0 NADH(P)-binding Response_reg PF00072.19 XP_011276442.1 - 0.079 12.9 0.0 0.32 11.0 0.0 2.1 1 0 0 1 1 1 0 Response regulator receiver domain AAA_33 PF13671.1 XP_011276442.1 - 0.099 12.5 0.2 1.1 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain PS_Dcarbxylase PF02666.10 XP_011276443.1 - 1.6e-54 184.2 0.0 2.9e-54 183.4 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 XP_011276443.1 - 2.2e-20 72.3 0.0 2.2e-11 43.4 0.1 2.9 2 0 0 2 2 2 2 C2 domain CEP76-C2 PF15627.1 XP_011276443.1 - 0.082 12.4 0.0 0.28 10.6 0.0 1.8 2 0 0 2 2 2 0 CEP76 C2 domain RNR_inhib PF08591.5 XP_011276443.1 - 0.12 13.2 8.0 4.6 8.2 0.0 2.7 2 0 0 2 2 2 0 Ribonucleotide reductase inhibitor DUF3668 PF12416.3 XP_011276443.1 - 0.14 11.2 2.8 1.6 7.8 0.0 2.8 3 0 0 3 3 3 0 Cep120 protein DNA_pol_E_B PF04042.11 XP_011276444.1 - 1.2e-47 161.8 0.1 1.6e-47 161.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B tRNA-synt_1g PF09334.6 XP_011276445.1 - 1.4e-103 346.6 0.3 1.4e-102 343.3 0.2 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 XP_011276445.1 - 1.3e-20 72.9 0.1 3e-10 38.7 0.0 4.1 1 1 2 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 XP_011276445.1 - 7.7e-06 25.2 0.9 0.0017 17.5 0.0 2.5 3 0 0 3 3 3 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.8 XP_011276445.1 - 0.0018 18.0 0.0 0.0039 16.9 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1f PF01921.13 XP_011276445.1 - 0.011 14.4 0.0 0.022 13.4 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (K) Yip1 PF04893.12 XP_011276446.1 - 1.2e-09 37.9 13.7 1.8e-09 37.3 9.5 1.3 1 0 0 1 1 1 1 Yip1 domain SMC_Nse1 PF07574.8 XP_011276447.1 - 3.3e-29 101.9 1.7 1.4e-26 93.3 1.2 2.1 1 1 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 XP_011276447.1 - 1.1e-10 41.3 6.0 3.8e-10 39.5 4.1 1.9 1 1 1 2 2 2 2 RING-like domain DUF1803 PF08820.5 XP_011276447.1 - 0.0055 16.3 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1803) DUF2067 PF09840.4 XP_011276447.1 - 0.014 14.9 0.1 0.033 13.7 0.1 1.8 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2067) zf-HC5HC2H_2 PF13832.1 XP_011276447.1 - 0.041 13.8 1.6 0.081 12.9 1.1 1.5 1 0 0 1 1 1 0 PHD-zinc-finger like domain C1_1 PF00130.17 XP_011276447.1 - 0.067 12.9 2.2 0.12 12.1 1.5 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H PF13771.1 XP_011276447.1 - 0.55 10.4 5.8 1.5 8.9 4.1 1.6 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_2 PF13639.1 XP_011276447.1 - 1.8 8.4 6.4 3.3 7.5 4.5 1.5 1 0 0 1 1 1 0 Ring finger domain SPRY PF00622.23 XP_011276448.1 - 1.1e-06 28.7 0.0 4.8e-06 26.6 0.0 2.0 2 0 0 2 2 2 1 SPRY domain Abhydrolase_6 PF12697.2 XP_011276449.1 - 1.9e-32 113.0 0.0 2.4e-32 112.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 XP_011276449.1 - 2.4e-30 105.8 0.1 2.9e-30 105.5 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 XP_011276449.1 - 1.3e-11 44.4 0.0 1.4e-10 41.0 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 XP_011276449.1 - 1.9e-06 27.6 0.0 1.4e-05 24.8 0.0 2.3 2 1 1 3 3 3 1 Putative lysophospholipase FSH1 PF03959.8 XP_011276449.1 - 0.003 17.0 0.0 0.83 9.0 0.0 2.2 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Ndr PF03096.9 XP_011276449.1 - 0.01 14.3 0.0 0.014 13.9 0.0 1.2 1 0 0 1 1 1 0 Ndr family PFK PF00365.15 XP_011276451.1 - 1.1e-169 562.7 4.1 1.6e-124 414.4 2.9 2.1 2 0 0 2 2 2 2 Phosphofructokinase Peptidase_S7 PF00949.16 XP_011276451.1 - 0.013 14.9 0.0 0.033 13.5 0.0 1.7 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease Av_adeno_fibre PF06536.6 XP_011276451.1 - 0.11 12.2 0.0 12 5.7 0.0 2.5 2 0 0 2 2 2 0 Avian adenovirus fibre MFS_1 PF07690.11 XP_011276452.1 - 4.1e-34 117.8 24.4 7.2e-34 117.0 15.8 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily zf-RING_2 PF13639.1 XP_011276453.1 - 3.4e-12 45.9 4.3 7.1e-12 44.9 3.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 XP_011276453.1 - 5.8e-08 32.3 4.1 1e-07 31.5 2.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 XP_011276453.1 - 1.7e-06 27.5 5.1 3.3e-06 26.6 3.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 XP_011276453.1 - 3.1e-06 27.0 4.6 8e-06 25.7 3.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 XP_011276453.1 - 2.1e-05 24.0 3.7 4e-05 23.1 2.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 XP_011276453.1 - 5.3e-05 23.2 1.9 0.00012 22.1 1.3 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 XP_011276453.1 - 0.014 15.0 1.5 0.014 15.0 1.1 2.1 3 0 0 3 3 3 0 RING-type zinc-finger zf-HC5HC2H_2 PF13832.1 XP_011276453.1 - 0.039 13.9 0.5 0.089 12.7 0.4 1.6 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 XP_011276453.1 - 0.083 13.0 1.0 0.2 11.8 0.7 1.7 1 0 0 1 1 1 0 PHD-like zinc-binding domain PHD PF00628.24 XP_011276453.1 - 0.086 12.5 3.6 0.15 11.7 2.5 1.4 1 0 0 1 1 1 0 PHD-finger zf-Apc11 PF12861.2 XP_011276453.1 - 0.12 12.2 2.1 0.32 10.8 1.5 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 XP_011276453.1 - 0.31 11.1 3.8 0.6 10.1 2.6 1.5 1 0 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.1 XP_011276453.1 - 1.3 8.6 5.1 2.6 7.6 3.5 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 XP_011276453.1 - 3.7 7.4 13.0 0.085 12.7 3.3 2.5 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 XP_011276454.1 - 8.2e-12 44.7 8.1 1.6e-11 43.8 5.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 XP_011276454.1 - 1.3e-08 34.7 2.4 3.5e-08 33.3 1.6 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 XP_011276454.1 - 1.6e-07 30.8 4.0 4e-07 29.5 2.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 XP_011276454.1 - 1.1e-06 28.2 6.9 2.5e-06 27.1 4.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 XP_011276454.1 - 1.2e-06 28.0 4.8 2.3e-06 27.1 3.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 XP_011276454.1 - 7.8e-05 22.7 7.4 0.00019 21.4 5.1 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 XP_011276454.1 - 0.00013 21.6 0.5 0.00024 20.7 0.3 1.5 1 0 0 1 1 1 1 RING-type zinc-finger YdjO PF14169.1 XP_011276454.1 - 0.0021 17.4 0.9 0.2 11.0 0.0 2.4 2 0 0 2 2 2 1 Cold-inducible protein YdjO zf-C3HC4_4 PF15227.1 XP_011276454.1 - 0.004 17.0 2.8 0.011 15.6 2.0 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING Vps39_2 PF10367.4 XP_011276454.1 - 0.005 16.9 3.8 0.0058 16.7 1.2 2.0 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 zf-Apc11 PF12861.2 XP_011276454.1 - 0.011 15.5 5.7 0.014 15.2 3.3 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 XP_011276454.1 - 0.016 15.2 0.9 0.043 13.8 0.6 1.8 1 1 0 1 1 1 0 RING-variant domain DUF3654 PF12376.3 XP_011276454.1 - 0.028 14.2 0.4 0.037 13.8 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3654) zf-RVT PF13966.1 XP_011276454.1 - 0.048 13.9 2.4 0.083 13.2 0.7 2.0 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase Rad50_zn_hook PF04423.9 XP_011276454.1 - 0.081 12.4 2.6 7.2 6.1 0.1 2.8 2 0 0 2 2 2 0 Rad50 zinc hook motif Prok-RING_1 PF14446.1 XP_011276454.1 - 0.092 12.4 6.5 0.55 9.9 3.0 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-HC5HC2H PF13771.1 XP_011276454.1 - 0.14 12.3 5.6 0.33 11.1 3.8 1.7 1 1 0 1 1 1 0 PHD-like zinc-binding domain PHD PF00628.24 XP_011276454.1 - 0.36 10.5 5.0 1 9.1 3.4 1.9 1 1 0 1 1 1 0 PHD-finger Sec63 PF02889.11 XP_011276455.1 - 2.4e-136 454.0 0.1 3.7e-92 308.9 0.1 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 XP_011276455.1 - 5.7e-53 178.8 2.2 7.6e-27 93.8 0.6 4.5 5 0 0 5 5 5 2 DEAD/DEAH box helicase ResIII PF04851.10 XP_011276455.1 - 1e-18 67.8 2.6 1.7e-08 34.5 0.1 3.9 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 XP_011276455.1 - 5.6e-17 61.3 0.0 3.7e-07 29.9 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain AAA_19 PF13245.1 XP_011276455.1 - 1.3e-06 28.0 0.0 0.029 14.1 0.0 2.8 2 0 0 2 2 2 2 Part of AAA domain AAA_22 PF13401.1 XP_011276455.1 - 2e-05 24.7 3.5 0.15 12.2 0.2 3.9 3 2 0 3 3 3 2 AAA domain PhoH PF02562.11 XP_011276455.1 - 0.00044 19.5 0.0 0.076 12.2 0.0 2.7 2 0 0 2 2 2 1 PhoH-like protein IstB_IS21 PF01695.12 XP_011276455.1 - 0.043 13.2 0.2 13 5.1 0.0 3.8 4 0 0 4 4 4 0 IstB-like ATP binding protein SET PF00856.23 XP_011276456.1 - 0.0055 17.0 0.0 0.013 15.7 0.0 1.8 1 1 0 1 1 1 1 SET domain PUB PF09409.5 XP_011276456.1 - 0.035 13.8 1.4 0.23 11.2 0.4 2.4 2 0 0 2 2 2 0 PUB domain DUF2361 PF10153.4 XP_011276457.1 - 6.9e-35 119.6 17.3 6.9e-35 119.6 12.0 1.7 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2361) ERCC4 PF02732.10 XP_011276457.1 - 3.6 7.3 8.1 15 5.2 0.0 2.2 1 1 1 2 2 2 0 ERCC4 domain DnaJ_CXXCXGXG PF00684.14 XP_011276458.1 - 0.0032 17.5 5.4 0.12 12.3 0.9 2.2 2 0 0 2 2 2 2 DnaJ central domain Cytochrome_C7 PF14522.1 XP_011276458.1 - 0.0092 15.6 0.6 0.074 12.7 0.4 2.2 2 0 0 2 2 2 1 Cytochrome c7 Cytochrom_c3_2 PF14537.1 XP_011276458.1 - 0.014 15.7 0.3 0.048 14.0 0.2 1.9 2 0 0 2 2 2 0 Cytochrome c3 HypA PF01155.14 XP_011276458.1 - 0.29 10.8 1.8 0.43 10.2 0.5 1.7 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family DUF605 PF04652.11 XP_011276458.1 - 4.4 6.6 9.6 4.7 6.5 6.7 1.2 1 0 0 1 1 1 0 Vta1 like GTP_cyclohydroI PF01227.17 XP_011276459.1 - 9.2e-77 256.3 0.2 1.1e-76 256.0 0.1 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 XP_011276459.1 - 7e-06 25.9 0.0 1.7e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 QueF-like protein DEAD PF00270.24 XP_011276460.1 - 5.7e-45 152.8 0.1 3.1e-44 150.4 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 XP_011276460.1 - 8.5e-22 76.8 0.0 2e-21 75.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 XP_011276460.1 - 1.6e-20 72.3 0.2 3.8e-20 71.1 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) DUF3347 PF11827.3 XP_011276460.1 - 3.3 7.6 16.2 5.9 6.8 11.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) Mpp10 PF04006.7 XP_011276460.1 - 3.4 5.9 30.5 4.9 5.3 21.2 1.1 1 0 0 1 1 1 0 Mpp10 protein Nop14 PF04147.7 XP_011276460.1 - 4.7 5.0 26.7 7 4.4 18.5 1.2 1 0 0 1 1 1 0 Nop14-like family AAA_23 PF13476.1 XP_011276460.1 - 4.9 7.4 18.2 1.7e+02 2.4 0.0 2.8 3 1 0 3 3 3 0 AAA domain SYF2 PF08231.7 XP_011276461.1 - 0.026 14.6 0.6 0.026 14.6 0.4 1.7 2 0 0 2 2 2 0 SYF2 splicing factor Mvb12 PF09452.5 XP_011276461.1 - 0.18 11.9 2.7 0.73 10.0 0.3 2.4 2 0 0 2 2 2 0 ESCRT-I subunit Mvb12 Response_reg PF00072.19 XP_011276462.1 - 3.2e-19 68.9 0.0 4.7e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain CPDase PF07823.6 XP_011276463.1 - 4.8e-26 91.4 0.0 5.3e-26 91.3 0.0 1.0 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein Glucosamine_iso PF01182.15 XP_011276464.1 - 4.3e-54 183.2 0.0 5e-54 183.0 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase A_deaminase PF00962.17 XP_011276465.1 - 3.6e-44 151.0 0.0 1.7e-43 148.8 0.0 2.1 1 1 0 1 1 1 1 Adenosine/AMP deaminase DHC_N1 PF08385.7 XP_011276466.1 - 1.8e-128 429.4 32.0 1.8e-128 429.4 22.2 5.6 4 1 1 6 6 6 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 XP_011276466.1 - 2.2e-103 345.9 18.4 2.2e-103 345.9 12.7 5.9 6 0 0 6 6 5 1 Dynein heavy chain, N-terminal region 2 Dynein_heavy PF03028.10 XP_011276466.1 - 1.4e-72 244.8 0.0 1.4e-72 244.8 0.0 2.1 3 0 0 3 3 2 1 Dynein heavy chain and region D6 of dynein motor AAA_6 PF12774.2 XP_011276466.1 - 3.6e-69 232.8 0.0 1.7e-68 230.6 0.0 2.2 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_9 PF12781.2 XP_011276466.1 - 3.9e-36 124.0 0.9 3.8e-35 120.7 0.2 2.7 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 AAA_8 PF12780.2 XP_011276466.1 - 2.7e-29 101.9 0.1 7.7e-29 100.4 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 MT PF12777.2 XP_011276466.1 - 1.1e-27 96.7 7.6 3.5e-27 95.0 5.2 1.9 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 XP_011276466.1 - 5e-26 91.0 0.0 6e-13 48.7 0.0 6.4 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA_7 PF12775.2 XP_011276466.1 - 1.2e-25 90.1 0.1 9.5e-25 87.1 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA PF00004.24 XP_011276466.1 - 7.7e-15 55.2 0.6 0.0067 16.6 0.0 7.1 6 0 0 6 6 6 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 XP_011276466.1 - 4.3e-13 49.5 0.7 0.0028 17.7 0.0 7.0 5 1 1 6 6 5 2 AAA domain AAA_16 PF13191.1 XP_011276466.1 - 1.3e-11 44.8 8.3 0.12 12.3 0.0 6.3 6 0 0 6 6 5 4 AAA ATPase domain AAA_17 PF13207.1 XP_011276466.1 - 1.2e-09 39.0 0.3 0.37 11.6 0.0 6.6 5 0 0 5 5 4 2 AAA domain T2SE PF00437.15 XP_011276466.1 - 1.8e-08 33.6 0.0 0.0071 15.2 0.0 4.5 5 0 0 5 5 5 2 Type II/IV secretion system protein AAA_25 PF13481.1 XP_011276466.1 - 4.9e-06 26.0 0.1 0.26 10.6 0.0 4.7 4 0 0 4 4 4 1 AAA domain AAA_33 PF13671.1 XP_011276466.1 - 7.5e-06 25.8 1.0 2.7 7.8 0.0 5.5 5 0 0 5 5 5 1 AAA domain DUF258 PF03193.11 XP_011276466.1 - 2.6e-05 23.4 0.2 3.2 6.9 0.0 3.9 3 0 0 3 3 3 2 Protein of unknown function, DUF258 IstB_IS21 PF01695.12 XP_011276466.1 - 5e-05 22.8 0.5 0.58 9.5 0.0 4.7 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_18 PF13238.1 XP_011276466.1 - 6.3e-05 23.2 14.2 0.88 9.8 0.0 6.6 7 0 0 7 7 5 2 AAA domain AAA_29 PF13555.1 XP_011276466.1 - 6.5e-05 22.3 0.3 0.56 9.7 0.1 3.8 3 0 0 3 3 3 1 P-loop containing region of AAA domain Zeta_toxin PF06414.7 XP_011276466.1 - 0.00016 20.8 0.0 0.27 10.3 0.0 4.1 3 0 0 3 3 3 1 Zeta toxin AAA_19 PF13245.1 XP_011276466.1 - 0.00018 21.1 0.3 0.43 10.3 0.0 3.5 3 0 0 3 3 3 1 Part of AAA domain FtsK_SpoIIIE PF01580.13 XP_011276466.1 - 0.0002 20.9 0.0 0.096 12.1 0.0 3.9 4 0 0 4 4 3 1 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 XP_011276466.1 - 0.00033 20.5 0.4 1.4 8.8 0.0 4.9 3 1 0 3 3 3 1 50S ribosome-binding GTPase RNA_helicase PF00910.17 XP_011276466.1 - 0.0025 17.9 6.3 19 5.4 0.0 6.0 6 0 0 6 6 5 0 RNA helicase MobB PF03205.9 XP_011276466.1 - 0.0037 16.9 5.8 2.5 7.8 0.2 4.6 5 0 0 5 5 5 1 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 XP_011276466.1 - 0.0081 15.8 0.0 0.0081 15.8 0.0 4.7 5 0 0 5 5 4 1 NACHT domain Mg_chelatase PF01078.16 XP_011276466.1 - 0.0088 15.2 2.3 1.3 8.1 0.0 3.8 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 XP_011276466.1 - 0.026 14.0 7.6 0.75 9.3 0.1 4.9 5 0 0 5 5 3 0 AAA domain AAA_28 PF13521.1 XP_011276466.1 - 0.047 13.6 4.6 58 3.5 0.0 5.3 5 0 0 5 5 5 0 AAA domain AAA_30 PF13604.1 XP_011276466.1 - 1.3 8.5 9.5 17 4.9 0.2 4.7 5 1 0 5 5 4 0 AAA domain CoA_transf_3 PF02515.12 XP_011276467.1 - 9.4e-36 122.8 0.0 7.5e-33 113.3 0.0 2.2 2 0 0 2 2 2 2 CoA-transferase family III MFS_1 PF07690.11 XP_011276468.1 - 3.2e-34 118.1 24.9 3.4e-34 118.1 16.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Acyl_transf_3 PF01757.17 XP_011276468.1 - 0.042 12.6 21.4 0.047 12.5 1.3 2.2 2 0 0 2 2 2 0 Acyltransferase family Abhydrolase_6 PF12697.2 XP_011276469.1 - 1.4e-17 64.3 0.0 2.1e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 XP_011276469.1 - 4.1e-12 46.1 1.4 1.8e-05 24.4 0.0 2.8 3 0 0 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 XP_011276469.1 - 3.4e-07 30.1 0.0 1.1e-06 28.4 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 XP_011276469.1 - 0.00059 19.1 0.0 0.0066 15.6 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 XP_011276469.1 - 0.00059 19.6 0.0 0.61 9.9 0.0 2.9 3 0 0 3 3 3 2 Putative lysophospholipase Lipase_3 PF01764.20 XP_011276469.1 - 0.0011 18.6 0.0 0.002 17.7 0.0 1.6 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_2 PF02230.11 XP_011276469.1 - 0.02 14.3 0.0 1.5 8.1 0.0 2.5 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 XP_011276469.1 - 0.027 14.0 0.0 0.052 13.1 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF676 PF05057.9 XP_011276469.1 - 0.037 13.3 0.1 0.099 11.9 0.0 1.7 1 1 0 1 1 1 0 Putative serine esterase (DUF676) Thioesterase PF00975.15 XP_011276469.1 - 0.1 12.8 0.0 14 5.7 0.0 2.3 2 0 0 2 2 2 0 Thioesterase domain CN_hydrolase PF00795.17 XP_011276470.1 - 1.1e-26 93.3 0.0 1.7e-26 92.7 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 XP_011276470.1 - 2.6e-24 85.4 0.0 1.3e-23 83.1 0.0 2.0 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.16 XP_011276470.1 - 0.034 13.6 0.0 0.06 12.8 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase RRM_1 PF00076.17 XP_011276471.1 - 6.9e-27 92.8 0.5 2.7e-16 58.9 0.3 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 XP_011276471.1 - 9.8e-17 60.7 0.1 2.2e-10 40.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 XP_011276471.1 - 7.5e-14 51.3 0.0 6.2e-09 35.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 XP_011276471.1 - 0.00092 19.0 0.1 0.85 9.4 0.0 2.1 2 0 0 2 2 2 2 RNA binding motif SPOR PF05036.8 XP_011276471.1 - 0.027 14.6 0.1 0.24 11.5 0.0 2.3 1 1 1 2 2 2 0 Sporulation related domain NAD_binding_10 PF13460.1 XP_011276472.1 - 9.2e-08 32.2 0.0 1.5e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 XP_011276472.1 - 6.2e-05 22.3 0.5 0.28 10.3 0.1 2.3 2 0 0 2 2 2 2 NmrA-like family HIM1 PF08732.5 XP_011276472.1 - 7.1e-05 21.4 0.0 0.0001 20.9 0.0 1.2 1 0 0 1 1 1 1 HIM1 Epimerase PF01370.16 XP_011276472.1 - 8.4e-05 22.1 0.7 0.001 18.5 0.1 2.5 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 XP_011276472.1 - 0.0055 16.9 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 XP_011276472.1 - 0.05 12.5 0.3 0.14 11.0 0.0 1.9 3 0 0 3 3 3 0 Male sterility protein 3Beta_HSD PF01073.14 XP_011276472.1 - 0.076 11.7 1.0 1.1 7.9 0.7 2.2 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family HIM1 PF08732.5 XP_011276473.1 - 9e-24 83.6 0.4 1.6e-21 76.2 0.1 2.5 1 1 1 2 2 2 2 HIM1 NAD_binding_10 PF13460.1 XP_011276473.1 - 8.7e-12 45.4 0.0 1.1e-11 45.0 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 XP_011276473.1 - 3.4e-05 23.2 0.0 6.4e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 XP_011276473.1 - 0.0012 19.1 0.1 0.0035 17.6 0.1 1.8 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 XP_011276473.1 - 0.0014 18.0 0.1 0.0021 17.5 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 XP_011276473.1 - 0.054 12.3 0.2 0.12 11.2 0.0 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 XP_011276473.1 - 0.11 11.3 0.1 0.89 8.3 0.0 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain CENP-O PF09496.5 XP_011276474.1 - 5.7e-19 68.1 0.6 5.7e-19 68.1 0.4 2.3 2 1 0 2 2 2 1 Cenp-O kinetochore centromere component DUF3295 PF11702.3 XP_011276474.1 - 0.044 12.7 3.7 0.058 12.3 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) ERp29 PF07749.7 XP_011276474.1 - 2 9.1 5.9 56 4.4 0.1 3.6 4 0 0 4 4 4 0 Endoplasmic reticulum protein ERp29, C-terminal domain Scs3p PF10261.4 XP_011276475.1 - 2.8e-37 128.0 8.2 3.8e-37 127.6 5.7 1.2 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM PAP2 PF01569.16 XP_011276475.1 - 0.00039 20.1 2.1 0.0019 17.9 1.4 2.1 1 1 0 1 1 1 1 PAP2 superfamily DUF912 PF06024.7 XP_011276475.1 - 0.0037 17.2 3.0 0.027 14.5 0.6 2.6 2 0 0 2 2 2 1 Nucleopolyhedrovirus protein of unknown function (DUF912) DivIC PF04977.10 XP_011276475.1 - 7.6 6.0 7.8 0.29 10.6 0.9 2.0 2 0 0 2 2 2 0 Septum formation initiator Scs3p PF10261.4 XP_011276476.1 - 1e-20 73.7 8.9 7.5e-20 70.9 6.2 1.9 1 1 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM PAP2 PF01569.16 XP_011276476.1 - 0.052 13.2 2.3 0.07 12.8 1.0 1.9 2 1 0 2 2 2 0 PAP2 superfamily Rgp1 PF08737.5 XP_011276477.1 - 9.9e-78 262.0 12.3 1.7e-77 261.2 8.5 1.4 1 0 0 1 1 1 1 Rgp1 Arrestin_C PF02752.17 XP_011276477.1 - 1.3e-05 25.3 7.9 0.00028 21.0 0.2 3.4 3 1 0 3 3 3 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 XP_011276477.1 - 0.00022 21.0 1.2 0.0031 17.3 0.1 3.3 4 0 0 4 4 4 1 Arrestin (or S-antigen), N-terminal domain DS PF01916.12 XP_011276477.1 - 0.74 8.8 3.2 2.7 7.0 2.2 1.8 1 1 0 1 1 1 0 Deoxyhypusine synthase Avl9 PF09794.4 XP_011276478.1 - 1.7e-134 448.1 5.3 2.4e-134 447.5 3.7 1.2 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.5 XP_011276478.1 - 4.2e-11 42.5 1.3 3.4e-06 26.7 0.0 3.3 3 0 0 3 3 3 2 Stabilization of polarity axis DUF2347 PF09804.4 XP_011276478.1 - 5.7e-06 25.8 1.4 5.7e-06 25.8 1.0 3.8 3 1 0 3 3 3 1 Uncharacterized conserved protein (DUF2347) DENN PF02141.16 XP_011276478.1 - 0.0043 16.8 0.3 0.13 11.9 0.2 3.0 2 1 0 2 2 2 1 DENN (AEX-3) domain Redoxin PF08534.5 XP_011276479.1 - 4.7e-23 81.3 0.1 5.7e-23 81.0 0.1 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 XP_011276479.1 - 3.8e-11 42.7 0.1 5.1e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Ferric_reduct PF01794.14 XP_011276480.1 - 4.8e-19 68.6 6.1 4.8e-19 68.6 4.2 2.8 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 XP_011276480.1 - 9.8e-16 57.5 0.0 2.2e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 XP_011276480.1 - 3e-11 43.4 0.0 5e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain ATP_bind_4 PF01902.12 XP_011276481.1 - 1.5e-45 155.2 0.1 4.1e-45 153.8 0.0 1.8 1 1 0 1 1 1 1 ATP-binding region Ribonuc_L-PSP PF01042.16 XP_011276481.1 - 7.3e-26 90.3 0.0 1.5e-12 47.3 0.0 2.4 2 0 0 2 2 2 2 Endoribonuclease L-PSP IMPDH PF00478.20 XP_011276481.1 - 0.21 10.4 0.0 0.36 9.6 0.0 1.3 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain Ribosomal_L6e PF01159.14 XP_011276482.1 - 2.8e-43 146.5 2.1 3.8e-43 146.1 1.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L6e Trypan_glycop PF00913.14 XP_011276483.1 - 0.01 14.7 2.2 0.02 13.7 1.5 1.5 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) CDC45 PF02724.9 XP_011276483.1 - 0.4 8.6 12.3 0.0056 14.7 3.7 1.4 2 0 0 2 2 2 0 CDC45-like protein DUF4611 PF15387.1 XP_011276483.1 - 3.1 8.0 13.1 1.8 8.7 4.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Sec1 PF00995.18 XP_011276484.1 - 1.2e-102 344.3 11.6 1.9e-102 343.7 8.0 1.2 1 0 0 1 1 1 1 Sec1 family dsrm PF00035.20 XP_011276485.1 - 0.0022 18.5 0.0 0.0046 17.5 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.21 XP_011276486.1 - 0.00068 20.0 0.1 0.0086 16.5 0.1 2.4 1 1 0 1 1 1 1 Ribonuclease III domain Glyco_trans_4_2 PF13477.1 XP_011276486.1 - 0.048 13.4 0.0 0.079 12.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase 4-like Ribonucleas_3_3 PF14622.1 XP_011276487.1 - 0.00028 20.8 0.1 0.0098 15.8 0.0 2.4 2 0 0 2 2 2 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 XP_011276487.1 - 0.57 10.6 4.8 1.2 9.6 2.1 2.7 2 1 0 2 2 2 0 Ribonuclease III domain Glyco_hydro_81 PF03639.8 XP_011276488.1 - 5.2e-217 722.1 12.6 6.5e-217 721.8 8.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 DUF4477 PF14780.1 XP_011276489.1 - 0.00019 20.8 1.9 0.0094 15.3 0.4 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4477) RNA_polI_A34 PF08208.6 XP_011276489.1 - 2.1 7.9 19.5 2.3 7.8 12.7 1.6 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 5_3_exonuc PF01367.15 XP_011276489.1 - 9.8 6.4 8.3 2.1 8.6 2.5 2.3 2 2 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold Spermine_synth PF01564.12 XP_011276491.1 - 1.2e-88 296.1 0.7 1.6e-88 295.8 0.5 1.0 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_31 PF13847.1 XP_011276491.1 - 1.3e-05 24.8 0.1 1.8e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF43 PF01861.11 XP_011276491.1 - 0.00031 19.8 0.0 0.00051 19.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF43 Methyltransf_18 PF12847.2 XP_011276491.1 - 0.00034 21.1 0.0 0.00071 20.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 XP_011276491.1 - 0.00097 18.2 0.0 0.0015 17.5 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_12 PF08242.7 XP_011276491.1 - 0.029 14.8 0.0 0.071 13.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain 3HCDH_N PF02737.13 XP_011276491.1 - 0.042 13.5 0.0 0.077 12.6 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain WD40 PF00400.27 XP_011276492.1 - 2.1e-05 24.2 0.1 0.046 13.6 0.1 3.9 3 0 0 3 3 3 1 WD domain, G-beta repeat CPSF_A PF03178.10 XP_011276492.1 - 0.0094 15.0 0.8 0.02 14.0 0.0 1.9 2 0 0 2 2 2 1 CPSF A subunit region NARP1 PF12569.3 XP_011276492.1 - 0.63 8.7 7.6 0.93 8.1 5.3 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 AA_permease PF00324.16 XP_011276493.1 - 9.6e-113 377.0 38.5 1.1e-112 376.8 26.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 XP_011276493.1 - 1.4e-32 112.8 44.0 1.8e-32 112.4 30.5 1.1 1 0 0 1 1 1 1 Amino acid permease Zn_clus PF00172.13 XP_011276494.1 - 3.8e-12 45.8 10.4 6.3e-12 45.1 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MCM PF00493.18 XP_011276494.1 - 0.0078 15.0 1.4 0.0078 15.0 1.0 1.6 2 0 0 2 2 2 1 MCM2/3/5 family Pro_dh PF01619.13 XP_011276495.1 - 8.4e-54 182.6 0.0 1.1e-53 182.2 0.0 1.2 1 0 0 1 1 1 1 Proline dehydrogenase Histidinol_dh PF00815.15 XP_011276495.1 - 0.082 11.5 0.1 0.13 10.8 0.1 1.2 1 0 0 1 1 1 0 Histidinol dehydrogenase Myb_DNA-binding PF00249.26 XP_011276496.1 - 0.014 15.4 1.3 0.05 13.6 0.0 2.3 2 0 0 2 2 2 0 Myb-like DNA-binding domain PAP_central PF04928.12 XP_011276497.1 - 1.1e-109 365.1 0.0 1.5e-109 364.6 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 XP_011276497.1 - 4.4e-46 156.2 0.2 8.3e-46 155.3 0.1 1.5 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 XP_011276497.1 - 2.3e-11 43.8 1.4 6.4e-11 42.4 0.1 2.3 2 0 0 2 2 2 1 Nucleotidyltransferase domain Peptidase_S49 PF01343.13 XP_011276497.1 - 0.05 13.3 0.1 0.086 12.6 0.1 1.3 1 0 0 1 1 1 0 Peptidase family S49 DUF1186 PF06685.6 XP_011276497.1 - 0.055 12.6 0.0 13 4.8 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1186) DUF2740 PF10872.3 XP_011276497.1 - 0.086 12.5 0.0 3.9 7.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2740) DUF2370 PF10176.4 XP_011276498.1 - 5.8e-75 251.6 0.2 5.8e-75 251.6 0.2 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF2370) SNF5 PF04855.7 XP_011276498.1 - 3.1e-62 210.2 6.6 3.1e-62 210.2 4.6 3.0 2 1 0 2 2 2 1 SNF5 / SMARCB1 / INI1 Gti1_Pac2 PF09729.4 XP_011276499.1 - 3.4e-42 144.1 4.8 2.9e-34 118.3 0.0 2.8 2 1 1 3 3 3 2 Gti1/Pac2 family Sugar_tr PF00083.19 XP_011276500.1 - 2e-132 441.9 35.4 2.4e-132 441.7 24.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 XP_011276500.1 - 4.2e-23 81.6 36.6 6e-21 74.5 17.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Mgr1 PF08602.5 XP_011276501.1 - 7.4e-57 193.0 8.3 1.2e-22 80.4 0.1 3.3 1 1 2 3 3 3 3 Mgr1-like, i-AAA protease complex subunit DUF1620 PF07774.8 XP_011276502.1 - 2e-69 233.1 3.3 2e-69 233.1 2.3 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF1620) PQQ PF01011.16 XP_011276502.1 - 8.8e-06 25.0 0.1 0.00022 20.5 0.0 3.1 3 0 0 3 3 3 1 PQQ enzyme repeat PQQ_2 PF13360.1 XP_011276502.1 - 7.1e-05 22.3 0.1 0.0042 16.5 0.0 2.5 2 0 0 2 2 2 1 PQQ-like domain DUF1312 PF07009.6 XP_011276502.1 - 0.18 11.6 3.9 0.15 11.8 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1312) DUF2577 PF10844.3 XP_011276502.1 - 1.9 8.5 7.7 0.47 10.5 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2577) dsrm PF00035.20 XP_011276503.1 - 5.7e-08 33.2 0.0 0.0071 16.8 0.0 3.4 3 0 0 3 3 3 2 Double-stranded RNA binding motif Acetyltransf_6 PF13480.1 XP_011276504.1 - 1.1e-05 25.3 0.0 2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain HATPase_c PF02518.21 XP_011276505.1 - 1.7e-09 37.3 1.6 2.2e-09 37.0 0.1 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.14 XP_011276505.1 - 5.6e-09 35.4 0.0 1.4e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 XP_011276505.1 - 1.3e-08 34.5 0.1 1.3e-08 34.5 0.1 2.9 3 1 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAP2 PF01569.16 XP_011276506.1 - 3.7e-12 46.0 6.5 3.7e-12 46.0 4.5 2.1 2 1 1 3 3 3 1 PAP2 superfamily PAP2_3 PF14378.1 XP_011276506.1 - 1.3e-05 24.8 8.3 2.9e-05 23.6 5.8 1.7 1 0 0 1 1 1 1 PAP2 superfamily Aminotran_5 PF00266.14 XP_011276508.1 - 5.7e-12 45.0 0.0 8.7e-12 44.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 XP_011276508.1 - 0.042 12.8 0.0 0.41 9.5 0.0 2.0 2 0 0 2 2 2 0 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 XP_011276508.1 - 0.23 10.4 0.0 0.4 9.6 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Zn_clus PF00172.13 XP_011276509.1 - 1.2e-08 34.7 7.7 2.1e-08 33.9 5.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EST1_DNA_bind PF10373.4 XP_011276510.1 - 8e-33 113.8 3.6 8e-33 113.8 2.5 1.9 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain EST1 PF10374.4 XP_011276510.1 - 2.1e-12 47.1 2.5 2.1e-12 47.1 1.7 3.1 3 0 0 3 3 3 1 Telomerase activating protein Est1 Topoisom_bac PF01131.15 XP_011276511.1 - 1.2e-98 330.6 0.1 1.4e-98 330.3 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 XP_011276511.1 - 1.8e-18 66.3 0.0 4e-18 65.2 0.0 1.6 1 0 0 1 1 1 1 Toprim domain Nucleoporin_FG PF13634.1 XP_011276512.1 - 0.037 14.2 193.2 0.3 11.3 38.8 5.4 1 1 2 3 3 3 0 Nucleoporin FG repeat region Arv1 PF04161.8 XP_011276513.1 - 4.9e-65 219.3 12.3 4.9e-65 219.3 8.6 1.6 2 0 0 2 2 2 1 Arv1-like family DUF221 PF02714.10 XP_011276514.1 - 1e-100 336.7 19.4 1.5e-100 336.1 13.4 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 XP_011276514.1 - 5.8e-40 136.4 2.5 6.7e-40 136.2 0.1 2.3 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 XP_011276514.1 - 1.8e-15 57.2 1.0 6.2e-15 55.4 0.7 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4463) RRM_6 PF14259.1 XP_011276514.1 - 0.0096 15.8 0.0 3.2 7.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PI3Ka PF00613.15 XP_011276515.1 - 9e-59 197.7 5.3 1.4e-58 197.0 3.7 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 XP_011276515.1 - 1.2e-45 155.8 0.0 8e-45 153.1 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 XP_011276515.1 - 2.3e-30 105.2 0.5 5.4e-30 104.0 0.3 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 CompInhib_SCIN PF11546.3 XP_011276515.1 - 0.00056 19.7 0.6 0.0023 17.7 0.4 2.0 1 0 0 1 1 1 1 Staphylococcal complement inhibitor SCIN DEAD PF00270.24 XP_011276516.1 - 3.7e-33 114.4 0.2 1.3e-32 112.6 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 XP_011276516.1 - 7.7e-22 76.9 0.5 5.5e-21 74.2 0.4 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 XP_011276516.1 - 3.1e-06 27.1 0.0 5.7e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 XP_011276516.1 - 0.0016 17.7 0.0 0.051 12.8 0.0 2.2 2 0 0 2 2 2 1 SecA DEAD-like domain zf-CCCH_2 PF14608.1 XP_011276517.1 - 0.0014 18.5 6.4 0.0027 17.6 4.5 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type CoaE PF01121.15 XP_011276518.1 - 7e-58 194.9 0.0 8.4e-58 194.7 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.1 XP_011276518.1 - 1.4e-05 25.8 0.1 4.6e-05 24.2 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 XP_011276518.1 - 0.002 18.0 0.1 0.03 14.2 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.1 XP_011276518.1 - 0.0025 18.1 0.1 0.008 16.4 0.1 1.8 1 1 0 1 1 1 1 AAA domain SKI PF01202.17 XP_011276518.1 - 0.15 11.9 0.1 0.95 9.3 0.0 2.0 2 0 0 2 2 2 0 Shikimate kinase ApbA_C PF08546.6 XP_011276519.1 - 4.3e-14 52.5 0.0 6.9e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 XP_011276519.1 - 1.6e-06 27.6 0.0 3.3e-06 26.5 0.0 1.5 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA E2_bind PF08825.5 XP_011276519.1 - 0.018 14.7 1.9 0.04 13.6 0.6 2.0 2 0 0 2 2 2 0 E2 binding domain SET PF00856.23 XP_011276520.1 - 2.9e-16 60.1 0.0 9.1e-16 58.5 0.0 1.8 1 1 0 1 1 1 1 SET domain BPL_LplA_LipB PF03099.14 XP_011276521.1 - 1.7e-16 60.3 0.0 3.6e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family FHA PF00498.21 XP_011276522.1 - 4.7e-13 49.0 2.8 6.6e-13 48.5 0.1 2.7 3 0 0 3 3 3 1 FHA domain Spectrin PF00435.16 XP_011276522.1 - 0.084 13.1 15.6 1.8 8.9 1.4 2.7 2 0 0 2 2 2 0 Spectrin repeat TMF_TATA_bd PF12325.3 XP_011276522.1 - 0.23 11.1 24.4 1.9 8.2 7.4 2.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF1664 PF07889.7 XP_011276522.1 - 2 8.2 14.4 2 8.2 2.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4407 PF14362.1 XP_011276522.1 - 6.7 5.5 7.8 11 4.8 5.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MCM PF00493.18 XP_011276523.1 - 3.8e-139 463.0 0.0 5.8e-139 462.5 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 XP_011276523.1 - 1.6e-22 80.2 1.0 1.6e-22 80.2 0.7 2.9 3 1 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.16 XP_011276523.1 - 5.2e-06 25.7 0.0 0.0003 20.0 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 XP_011276523.1 - 4e-05 23.3 0.0 0.00015 21.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 XP_011276523.1 - 0.0013 18.3 0.0 0.0043 16.6 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) CAF1A PF12253.3 XP_011276524.1 - 2.5e-09 37.0 11.3 2.5e-09 37.0 7.8 4.0 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.3 XP_011276524.1 - 1.1e-05 24.8 97.0 1.1e-05 24.8 67.3 2.5 2 1 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal SR-25 PF10500.4 XP_011276525.1 - 0.18 11.2 7.2 0.32 10.4 5.0 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DASH_Spc19 PF08287.6 XP_011276526.1 - 6.6e-35 119.9 12.7 9.7e-35 119.4 8.8 1.2 1 0 0 1 1 1 1 Spc19 YbbR PF07949.7 XP_011276526.1 - 0.025 14.6 0.3 0.14 12.2 0.0 2.3 1 1 1 2 2 2 0 YbbR-like protein Baculo_PEP_C PF04513.7 XP_011276526.1 - 0.08 12.7 5.3 0.38 10.5 3.7 2.0 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Peptidase_A3 PF02160.10 XP_011276526.1 - 0.11 12.0 2.2 0.12 11.9 1.5 1.2 1 0 0 1 1 1 0 Cauliflower mosaic virus peptidase (A3) S1 PF00575.18 XP_011276526.1 - 0.23 11.5 1.6 11 6.2 0.1 2.5 2 1 0 2 2 2 0 S1 RNA binding domain Atg14 PF10186.4 XP_011276526.1 - 0.25 10.2 6.5 0.29 10.0 4.5 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4279 PF14106.1 XP_011276526.1 - 0.42 10.4 3.3 4.2 7.2 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4279) LMBR1 PF04791.11 XP_011276526.1 - 0.84 8.1 3.6 0.94 7.9 2.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein ING PF12998.2 XP_011276526.1 - 2 8.6 10.8 54 4.1 7.5 2.1 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding Rogdi_lz PF10259.4 XP_011276527.1 - 5e-54 183.2 7.6 5.8e-54 183.0 5.3 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein Coq4 PF05019.8 XP_011276528.1 - 3.8e-60 202.5 0.0 5.3e-60 202.1 0.0 1.2 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Transp_cyt_pur PF02133.10 XP_011276529.1 - 1.4e-68 231.4 37.1 1.9e-68 231.0 25.7 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Cation_efflux PF01545.16 XP_011276530.1 - 6e-56 189.5 2.8 6e-56 189.5 2.0 3.0 2 2 0 2 2 2 1 Cation efflux family Zip PF02535.17 XP_011276530.1 - 1.7e-05 23.9 16.4 1.7e-05 23.9 11.3 2.5 1 1 0 2 2 2 1 ZIP Zinc transporter CbtA PF09490.5 XP_011276530.1 - 0.14 11.4 4.1 23 4.1 2.1 3.4 4 1 0 4 4 4 0 Probable cobalt transporter subunit (CbtA) CKAP2_C PF15297.1 XP_011276530.1 - 0.15 10.8 3.5 0.24 10.1 2.4 1.2 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus DUF2946 PF11162.3 XP_011276530.1 - 2.5 8.3 11.2 2.2 8.5 1.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) ATP_bind_1 PF03029.12 XP_011276531.1 - 4.8e-75 252.1 0.1 5.4e-75 251.9 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein SIR2 PF02146.12 XP_011276532.1 - 5.8e-28 97.8 0.0 2.4e-27 95.7 0.0 2.0 1 1 0 1 1 1 1 Sir2 family DUF2387 PF09526.5 XP_011276532.1 - 0.2 11.5 0.0 0.2 11.5 0.0 3.4 2 2 1 3 3 3 0 Probable metal-binding protein (DUF2387) TIP49 PF06068.8 XP_011276533.1 - 1.9e-186 619.5 0.4 2.3e-186 619.3 0.3 1.0 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 XP_011276533.1 - 1.4e-10 40.6 2.3 2.1e-05 23.6 0.0 3.0 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 XP_011276533.1 - 2e-08 34.4 0.2 6.8e-05 23.0 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 XP_011276533.1 - 0.0017 18.3 0.1 0.67 9.9 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.7 XP_011276533.1 - 0.0038 16.3 0.1 0.0091 15.1 0.1 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.1 XP_011276533.1 - 0.0083 16.2 0.1 1.3 9.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 XP_011276533.1 - 0.0083 15.8 0.0 0.021 14.5 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 XP_011276533.1 - 0.026 14.4 0.1 0.055 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 XP_011276533.1 - 0.026 14.2 0.2 1.4 8.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 XP_011276533.1 - 0.029 13.5 0.2 2.2 7.3 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 XP_011276533.1 - 0.034 14.4 0.1 0.22 11.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 XP_011276533.1 - 0.051 13.0 0.1 9.8 5.6 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain DnaB_C PF03796.10 XP_011276533.1 - 0.08 11.8 0.0 0.15 10.9 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Sec1 PF00995.18 XP_011276534.1 - 1.5e-136 456.3 10.0 1.6e-136 456.2 6.9 1.0 1 0 0 1 1 1 1 Sec1 family Pkinase PF00069.20 XP_011276535.1 - 2e-43 148.4 0.0 3.6e-43 147.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.7 XP_011276535.1 - 2.3e-41 140.6 0.5 5.6e-41 139.4 0.4 1.7 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.12 XP_011276535.1 - 1.7e-24 86.3 0.0 1.1e-20 73.7 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase PQQ_2 PF13360.1 XP_011276535.1 - 2.3e-07 30.5 0.0 6.6e-07 29.0 0.0 1.8 1 1 0 1 1 1 1 PQQ-like domain PQQ PF01011.16 XP_011276535.1 - 8e-06 25.1 0.0 0.0085 15.5 0.0 3.0 3 0 0 3 3 3 2 PQQ enzyme repeat Kdo PF06293.9 XP_011276535.1 - 0.058 12.4 0.0 0.098 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Zn_clus PF00172.13 XP_011276536.1 - 2.7e-05 23.9 13.6 4.4e-05 23.3 9.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cpn60_TCP1 PF00118.19 XP_011276537.1 - 6.9e-150 499.8 5.9 7.9e-150 499.6 4.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Peptidase_M24 PF00557.19 XP_011276538.1 - 2.5e-48 164.3 0.1 3.1e-48 164.0 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 RGM_N PF06535.7 XP_011276538.1 - 0.00052 20.0 0.2 0.00088 19.3 0.1 1.3 1 0 0 1 1 1 1 Repulsive guidance molecule (RGM) N-terminus zf-MYND PF01753.13 XP_011276538.1 - 0.0034 17.2 3.9 0.0091 15.8 2.7 1.8 1 0 0 1 1 1 1 MYND finger ATP-cone PF03477.11 XP_011276538.1 - 0.0047 17.3 0.1 0.92 9.9 0.0 2.3 2 0 0 2 2 2 2 ATP cone domain His_Phos_1 PF00300.17 XP_011276539.1 - 5.7e-11 42.7 0.2 1.8e-10 41.1 0.0 2.0 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) TPR_12 PF13424.1 XP_011276540.1 - 8.7e-07 28.7 3.7 0.35 10.8 0.0 4.9 4 2 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 XP_011276540.1 - 1.5e-05 24.4 5.6 0.36 10.7 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 XP_011276540.1 - 5.5e-05 22.7 2.9 0.58 10.2 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 XP_011276540.1 - 0.00012 21.6 2.6 0.019 14.7 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 XP_011276540.1 - 0.00081 19.6 0.9 0.26 11.8 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 XP_011276540.1 - 0.00083 18.8 3.4 1.1 8.9 0.0 4.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.1 XP_011276540.1 - 0.0043 16.6 1.5 2.2 8.0 0.0 3.9 3 1 1 4 4 4 1 TPR repeat Syntaxin-6_N PF09177.6 XP_011276540.1 - 0.014 15.7 1.5 0.073 13.4 0.1 2.7 2 1 1 3 3 3 0 Syntaxin 6, N-terminal HP_OMP PF01856.12 XP_011276540.1 - 0.075 12.8 0.0 2.1 8.1 0.0 2.2 2 0 0 2 2 2 0 Helicobacter outer membrane protein TPR_17 PF13431.1 XP_011276540.1 - 0.13 12.5 3.6 12 6.3 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 XP_011276540.1 - 0.15 12.0 0.5 3.1 7.8 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat DZR PF12773.2 XP_011276541.1 - 0.011 15.5 0.2 0.021 14.6 0.1 1.4 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.1 XP_011276541.1 - 0.25 10.8 2.5 0.46 10.0 1.7 1.5 1 0 0 1 1 1 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 XP_011276541.1 - 0.55 9.5 2.5 1 8.6 1.7 1.4 1 0 0 1 1 1 0 zinc-ribbon domain Pkinase PF00069.20 XP_011276542.1 - 3.6e-76 255.7 0.0 4.3e-76 255.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011276542.1 - 1.3e-33 116.1 0.0 1.6e-33 115.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 XP_011276542.1 - 0.00029 19.8 0.0 0.00076 18.5 0.0 1.8 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 XP_011276542.1 - 0.011 14.8 0.4 0.024 13.6 0.2 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 XP_011276542.1 - 0.015 15.0 0.3 0.048 13.3 0.2 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family PPR_2 PF13041.1 XP_011276543.1 - 5.6e-12 45.4 3.8 0.0045 16.9 0.1 5.0 1 1 4 5 5 5 5 PPR repeat family PPR PF01535.15 XP_011276543.1 - 4.6e-07 29.3 4.9 0.045 13.7 0.1 5.7 6 0 0 6 6 6 2 PPR repeat PPR_3 PF13812.1 XP_011276543.1 - 4.7e-06 26.4 1.5 4.9 7.6 0.0 5.1 5 0 0 5 5 5 2 Pentatricopeptide repeat domain DUF1981 PF09324.5 XP_011276543.1 - 0.031 13.7 0.2 3 7.4 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1981) Hemagglutinin PF00509.13 XP_011276543.1 - 1.6 6.7 6.7 3.7 5.5 0.9 2.3 2 0 0 2 2 2 0 Haemagglutinin TFIID_30kDa PF03540.8 XP_011276545.1 - 2.1e-22 78.6 0.2 3.4e-22 78.0 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit CBFD_NFYB_HMF PF00808.18 XP_011276545.1 - 0.075 13.1 0.0 0.2 11.7 0.0 1.7 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone POX PF07526.6 XP_011276545.1 - 0.11 12.6 0.3 0.46 10.7 0.0 1.8 2 0 0 2 2 2 0 Associated with HOX DUF2946 PF11162.3 XP_011276546.1 - 0.17 12.0 3.2 0.25 11.5 2.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2946) Pep3_Vps18 PF05131.9 XP_011276547.1 - 1.9e-41 140.9 1.0 5.5e-41 139.4 0.4 2.1 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 XP_011276547.1 - 3.2e-12 46.2 20.4 2.3e-11 43.4 2.9 3.8 3 0 0 3 3 3 2 Region in Clathrin and VPS Vps39_2 PF10367.4 XP_011276547.1 - 4.3e-06 26.8 0.3 1.1e-05 25.5 0.2 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-RING_2 PF13639.1 XP_011276547.1 - 4.6e-05 23.1 4.5 0.0001 22.0 3.1 1.6 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 XP_011276547.1 - 0.0031 17.1 1.9 0.0031 17.1 1.3 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 XP_011276547.1 - 0.0076 16.2 1.3 0.0076 16.2 0.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 XP_011276547.1 - 0.0085 15.7 2.2 0.0085 15.7 1.5 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 XP_011276547.1 - 0.071 12.7 2.7 0.15 11.7 0.2 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) LSM PF01423.17 XP_011276548.1 - 1.3e-10 40.6 0.3 4.8e-10 38.8 0.2 1.7 1 1 0 1 1 1 1 LSM domain Tail_tube PF10618.4 XP_011276548.1 - 0.053 13.2 0.0 0.07 12.8 0.0 1.2 1 0 0 1 1 1 0 Phage tail tube protein Sec5 PF15469.1 XP_011276549.1 - 4.7e-46 156.7 11.3 4.7e-46 156.7 7.8 4.3 3 2 1 4 4 4 1 Exocyst complex component Sec5 PIP5K PF01504.13 XP_011276550.1 - 1.7e-82 276.3 1.9 3.4e-82 275.3 1.3 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Transthyretin PF00576.16 XP_011276551.1 - 3.4e-29 100.9 0.1 1.6e-27 95.5 0.1 2.2 1 1 0 1 1 1 1 HIUase/Transthyretin family Stn1 PF10451.4 XP_011276552.1 - 4.7e-21 74.7 0.3 1e-20 73.6 0.2 1.5 1 0 0 1 1 1 1 Telomere regulation protein Stn1 Methyltransf_8 PF05148.10 XP_011276553.1 - 1.4e-65 221.0 0.2 6.6e-65 218.8 0.1 1.9 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.7 XP_011276553.1 - 2.5e-08 34.2 0.0 1.3e-07 31.9 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 XP_011276553.1 - 2.2e-05 24.0 0.1 5.5e-05 22.8 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 XP_011276553.1 - 0.042 13.2 0.0 1.5 8.1 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_25 PF13649.1 XP_011276553.1 - 0.045 14.1 0.0 0.14 12.5 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Ndc1_Nup PF09531.5 XP_011276553.1 - 0.069 11.5 10.3 0.1 10.9 7.2 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Methyltransf_32 PF13679.1 XP_011276553.1 - 0.85 9.2 0.0 0.85 9.2 0.0 2.6 3 1 0 3 3 3 0 Methyltransferase domain NAM-associated PF14303.1 XP_011276553.1 - 5.3 7.3 31.9 22 5.3 14.4 3.5 3 1 0 3 3 3 0 No apical meristem-associated C-terminal domain Neur_chan_memb PF02932.11 XP_011276553.1 - 5.3 6.8 8.4 1.5 8.6 3.6 1.8 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region TLP-20 PF06088.6 XP_011276553.1 - 7.6 6.1 17.6 1.1 8.9 9.0 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) DDE_1 PF03184.14 XP_011276554.1 - 7.3e-44 149.4 0.4 2.4e-43 147.8 0.1 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 XP_011276554.1 - 1.8e-13 50.1 0.2 1.2e-12 47.4 0.0 2.3 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain DUF846 PF05832.7 XP_011276555.1 - 2.6e-42 143.9 6.5 3e-42 143.6 4.5 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) DUF4149 PF13664.1 XP_011276555.1 - 0.00021 21.3 0.7 0.0003 20.8 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4149) Lysis_S PF04971.7 XP_011276555.1 - 0.79 9.4 2.7 0.67 9.6 0.8 1.9 2 1 0 2 2 2 0 Lysis protein S Sec34 PF04136.10 XP_011276556.1 - 2.7e-31 108.4 7.8 2.7e-31 108.4 5.4 3.0 4 0 0 4 4 4 1 Sec34-like family UPF0160 PF03690.8 XP_011276557.1 - 1.4e-128 428.8 0.0 1.6e-128 428.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) RhoGAP PF00620.22 XP_011276558.1 - 2.5e-42 144.0 0.3 5.1e-41 139.8 0.0 2.9 2 0 0 2 2 2 1 RhoGAP domain RasGEF PF00617.14 XP_011276558.1 - 5.9e-26 91.3 0.5 5.4e-25 88.2 0.2 2.7 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 XP_011276558.1 - 2.5e-16 59.6 6.9 7.9e-16 58.0 1.0 4.4 3 1 0 3 3 3 1 RasGEF N-terminal motif PH_9 PF15410.1 XP_011276558.1 - 0.024 14.7 0.2 0.39 10.8 0.0 2.6 2 0 0 2 2 2 0 Pleckstrin homology domain 60KD_IMP PF02096.15 XP_011276559.1 - 2.7e-40 138.1 2.5 2.7e-40 138.1 1.7 2.0 2 0 0 2 2 2 1 60Kd inner membrane protein HemY_N PF07219.8 XP_011276559.1 - 0.13 11.7 1.1 0.43 10.1 0.7 1.9 1 0 0 1 1 1 0 HemY protein N-terminus Lipoprotein_10 PF03202.8 XP_011276559.1 - 0.29 11.1 3.4 3.6 7.6 0.5 2.3 2 0 0 2 2 2 0 Putative mycoplasma lipoprotein, C-terminal region RELT PF12606.3 XP_011276559.1 - 0.51 9.5 0.0 0.51 9.5 0.0 1.8 2 0 0 2 2 2 0 Tumour necrosis factor receptor superfamily member 19 MNE1 PF13762.1 XP_011276560.1 - 0.017 15.1 4.4 1.9 8.5 0.1 2.8 2 1 1 3 3 3 0 Mitochondrial splicing apparatus component tRNA-synt_2 PF00152.15 XP_011276560.1 - 0.072 11.8 0.2 0.12 11.1 0.1 1.3 1 0 0 1 1 1 0 tRNA synthetases class II (D, K and N) Aminotran_1_2 PF00155.16 XP_011276561.1 - 3.5e-21 75.5 0.0 4.8e-21 75.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 XP_011276561.1 - 0.011 14.3 0.0 0.021 13.3 0.0 1.4 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase DUF3533 PF12051.3 XP_011276562.1 - 1.9e-118 395.5 20.0 2.3e-118 395.2 13.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) Gifsy-2 PF13856.1 XP_011276563.1 - 0.0036 17.4 1.1 0.77 9.9 0.0 2.2 2 0 0 2 2 2 2 ATP-binding sugar transporter from pro-phage DUF2334 PF10096.4 XP_011276563.1 - 0.15 11.4 4.1 3.1 7.1 0.2 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2334) Retinal PF15449.1 XP_011276563.1 - 7.9 3.9 34.2 8.8 3.8 23.7 1.2 1 0 0 1 1 1 0 Retinal protein SAICAR_synt PF01259.13 XP_011276564.1 - 4e-105 350.4 0.4 4.7e-105 350.1 0.3 1.0 1 0 0 1 1 1 1 SAICAR synthetase Pkinase PF00069.20 XP_011276565.1 - 1.3e-50 171.9 0.1 2e-50 171.3 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011276565.1 - 4.1e-31 108.0 0.0 1.2e-30 106.4 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Filament PF00038.16 XP_011276565.1 - 0.00022 20.8 4.8 0.00032 20.2 3.3 1.2 1 0 0 1 1 1 1 Intermediate filament protein Kinase-like PF14531.1 XP_011276565.1 - 0.00087 18.3 0.0 0.0018 17.2 0.0 1.6 1 1 0 1 1 1 1 Kinase-like DUF641 PF04859.7 XP_011276565.1 - 0.034 13.8 2.7 0.067 12.9 1.9 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) ATP-grasp PF02222.17 XP_011276566.1 - 3.4e-65 218.5 0.0 5.7e-65 217.8 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain AIRC PF00731.15 XP_011276566.1 - 4.6e-64 214.2 3.0 4.8e-64 214.1 1.0 1.8 2 0 0 2 2 2 1 AIR carboxylase ATP-grasp_4 PF13535.1 XP_011276566.1 - 3.6e-12 46.4 0.0 6.9e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 XP_011276566.1 - 1.2e-05 24.7 0.0 0.00017 21.0 0.0 2.3 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 XP_011276566.1 - 0.0015 17.3 0.0 0.035 12.8 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon 2-Hacid_dh_C PF02826.14 XP_011276566.1 - 0.002 17.3 0.1 0.0059 15.7 0.0 1.9 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GARS_A PF01071.14 XP_011276566.1 - 0.0051 16.3 0.1 0.012 15.1 0.0 1.7 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain XdhC_C PF13478.1 XP_011276566.1 - 0.0059 16.9 0.0 0.037 14.3 0.0 2.3 2 0 0 2 2 2 1 XdhC Rossmann domain F420_oxidored PF03807.12 XP_011276566.1 - 0.017 15.5 0.3 0.18 12.2 0.1 2.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 XP_011276566.1 - 0.081 12.9 0.3 0.23 11.4 0.2 1.9 1 0 0 1 1 1 0 TrkA-N domain Zn_clus PF00172.13 XP_011276567.1 - 3.6e-09 36.3 4.1 6.9e-09 35.4 2.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zip PF02535.17 XP_011276567.1 - 0.46 9.4 3.0 0.91 8.4 2.1 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter PAT1 PF09770.4 XP_011276567.1 - 4.5 5.3 37.6 1.1 7.3 24.0 1.4 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 RGS PF00615.14 XP_011276569.1 - 9.9e-08 32.1 8.9 0.00028 20.9 0.4 3.4 3 1 0 3 3 3 2 Regulator of G protein signaling domain DUF4108 PF13390.1 XP_011276570.1 - 0.032 13.9 3.6 0.076 12.7 1.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4108) DUF4116 PF13475.1 XP_011276571.1 - 1.1 8.8 10.2 0.083 12.3 0.8 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4116) DUF2305 PF10230.4 XP_011276572.1 - 1.1e-65 221.6 0.9 1.6e-65 221.1 0.6 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 XP_011276572.1 - 0.00013 21.9 0.0 0.00023 21.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 XP_011276572.1 - 0.023 14.4 0.0 0.037 13.7 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF2240 PF09999.4 XP_011276572.1 - 0.076 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2240) NRDE PF05742.7 XP_011276573.1 - 2.1e-55 187.9 0.9 2.7e-55 187.6 0.6 1.1 1 0 0 1 1 1 1 NRDE protein Sulfate_transp PF00916.15 XP_011276575.1 - 4.6e-42 143.9 8.5 4.6e-42 143.9 5.9 2.6 2 0 0 2 2 2 1 Sulfate transporter family STAS PF01740.16 XP_011276575.1 - 4.1e-10 39.1 0.9 1e-09 37.8 0.6 1.6 1 0 0 1 1 1 1 STAS domain FAD_binding_6 PF00970.19 XP_011276576.1 - 7.8e-31 106.1 0.0 1.2e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 XP_011276576.1 - 6.1e-30 104.0 0.0 1e-29 103.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 XP_011276576.1 - 1.5e-06 28.2 0.0 0.00031 20.6 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 XP_011276576.1 - 0.0068 16.3 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain MS_channel PF00924.13 XP_011276576.1 - 0.039 13.2 0.0 0.039 13.2 0.0 1.5 2 0 0 2 2 2 0 Mechanosensitive ion channel AA_kinase PF00696.23 XP_011276577.1 - 7e-44 150.1 1.4 3.1e-43 148.0 0.0 2.0 2 0 0 2 2 2 1 Amino acid kinase family ACT PF01842.20 XP_011276577.1 - 4.4e-13 48.4 3.5 3.8e-08 32.6 0.1 3.0 3 0 0 3 3 3 2 ACT domain ACT_7 PF13840.1 XP_011276577.1 - 2.5e-10 39.7 1.4 2.9e-07 29.8 0.6 2.7 2 0 0 2 2 2 2 ACT domain GDA1_CD39 PF01150.12 XP_011276578.1 - 6.6e-131 436.7 0.1 9.1e-131 436.3 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.11 XP_011276578.1 - 0.014 14.6 0.0 0.03 13.5 0.0 1.4 1 1 0 1 1 1 0 Ppx/GppA phosphatase family TFIIB PF00382.14 XP_011276579.1 - 4.6e-40 135.2 3.6 6.9e-24 83.4 0.3 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 XP_011276579.1 - 6.9e-12 44.4 0.3 1.4e-11 43.4 0.2 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding Sigma70_r4_2 PF08281.7 XP_011276579.1 - 0.024 14.0 0.0 0.07 12.6 0.0 1.8 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_11 PF08279.7 XP_011276579.1 - 0.095 12.3 0.1 3 7.5 0.0 2.5 2 0 0 2 2 2 0 HTH domain HTH_Tnp_ISL3 PF13542.1 XP_011276579.1 - 0.13 11.4 0.0 23 4.2 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 GN3L_Grn1 PF08701.6 XP_011276580.1 - 1.2e-25 89.2 12.7 3.7e-25 87.6 8.8 1.9 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 XP_011276580.1 - 7.5e-21 74.2 0.4 3.2e-15 56.0 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 XP_011276580.1 - 1.9e-07 30.4 0.0 5.8e-06 25.6 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 XP_011276580.1 - 1.7e-05 24.3 0.2 0.014 14.8 0.0 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain DUF258 PF03193.11 XP_011276580.1 - 8.1e-05 21.8 0.5 0.00014 21.1 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 XP_011276580.1 - 0.00099 18.9 4.5 1 9.1 0.0 3.7 2 2 1 3 3 3 2 Dynamin family Miro PF08477.8 XP_011276580.1 - 0.0071 16.8 0.5 0.25 11.8 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein cobW PF02492.14 XP_011276580.1 - 0.053 12.9 0.3 1.4 8.2 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 XP_011276580.1 - 0.088 11.5 0.1 0.18 10.5 0.1 1.4 1 0 0 1 1 1 0 ArgK protein Pox_Ag35 PF03286.9 XP_011276580.1 - 0.18 11.3 12.4 0.27 10.7 8.0 1.8 1 1 0 1 1 1 0 Pox virus Ag35 surface protein AAA_18 PF13238.1 XP_011276580.1 - 0.24 11.6 3.8 0.97 9.7 0.0 2.7 2 1 0 2 2 2 0 AAA domain Na_trans_assoc PF06512.8 XP_011276580.1 - 8.7 6.2 14.2 16 5.4 9.8 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated CAP_GLY PF01302.20 XP_011276581.1 - 7.5e-06 25.5 0.1 2.1e-05 24.1 0.1 1.7 1 1 0 1 1 1 1 CAP-Gly domain LRR_8 PF13855.1 XP_011276581.1 - 3.3e-05 23.5 9.3 3.3e-05 23.5 6.5 6.0 3 3 3 6 6 6 4 Leucine rich repeat LRR_4 PF12799.2 XP_011276581.1 - 7.5e-05 22.2 47.2 0.0044 16.6 6.4 6.4 5 3 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 XP_011276581.1 - 0.0014 18.5 25.5 0.43 10.7 0.3 7.2 8 0 0 8 8 8 2 Leucine Rich repeat LRR_1 PF00560.28 XP_011276581.1 - 0.0018 18.0 27.8 0.46 10.7 0.6 7.4 6 2 0 6 6 6 4 Leucine Rich Repeat LRR_7 PF13504.1 XP_011276581.1 - 0.21 11.9 16.9 3.6 8.2 0.1 6.3 7 0 0 7 7 7 0 Leucine rich repeat PUA PF01472.15 XP_011276582.1 - 4.5e-18 64.7 0.0 6.5e-18 64.2 0.0 1.2 1 0 0 1 1 1 1 PUA domain DUF1947 PF09183.5 XP_011276582.1 - 0.034 13.8 0.1 0.086 12.6 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1947) Helicase_C PF00271.26 XP_011276583.1 - 8.3e-20 70.4 0.0 3.1e-19 68.5 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 XP_011276583.1 - 2.5e-19 69.3 0.1 3.9e-18 65.5 0.0 3.0 3 0 0 3 3 3 1 DEAD/DEAH box helicase ResIII PF04851.10 XP_011276583.1 - 2e-17 63.6 0.0 2e-17 63.6 0.0 4.6 5 1 2 7 7 7 1 Type III restriction enzyme, res subunit Sec3_C PF09763.4 XP_011276584.1 - 2.5e-127 425.9 39.1 2.5e-127 425.9 27.1 2.5 3 0 0 3 3 3 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 XP_011276584.1 - 6.1e-26 90.1 0.1 1.8e-25 88.5 0.0 1.9 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH DUF2120 PF09893.4 XP_011276584.1 - 1.5 8.7 5.9 8.7 6.2 0.1 4.0 4 0 0 4 4 4 0 Uncharacterized protein conserved in archaea (DUF2120) HAD_2 PF13419.1 XP_011276585.1 - 2.8e-13 50.4 0.0 4.1e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 XP_011276585.1 - 8.8e-10 39.3 0.0 7.3e-09 36.3 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 XP_011276585.1 - 7.2e-06 25.6 0.1 1.5e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 XP_011276585.1 - 9.6e-05 22.6 0.0 0.00014 22.0 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF3883 PF13020.1 XP_011276585.1 - 0.014 15.1 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3883) Methyltransf_3 PF01596.12 XP_011276586.1 - 4.5e-15 55.2 0.0 6.1e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 XP_011276586.1 - 7.9e-08 33.0 0.0 1.2e-07 32.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.7 XP_011276586.1 - 0.0012 18.2 0.0 0.0018 17.5 0.0 1.3 1 0 0 1 1 1 1 Cephalosporin hydroxylase Methyltransf_18 PF12847.2 XP_011276586.1 - 0.0092 16.5 0.0 0.018 15.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 XP_011276586.1 - 0.022 14.3 0.0 0.048 13.2 0.0 1.5 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_32 PF13679.1 XP_011276586.1 - 0.12 12.0 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain LigB PF02900.13 XP_011276586.1 - 0.13 11.2 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Catalytic LigB subunit of aromatic ring-opening dioxygenase Utp8 PF10395.4 XP_011276587.1 - 2.3e-84 283.9 27.0 3.2e-84 283.5 18.7 1.2 1 0 0 1 1 1 1 Utp8 family SYF2 PF08231.7 XP_011276588.1 - 1.7e-22 80.2 25.3 6.3e-18 65.3 9.8 3.2 2 1 0 3 3 3 2 SYF2 splicing factor Hom_end_hint PF05203.11 XP_011276588.1 - 0.19 11.4 14.3 0.27 10.9 9.8 1.4 1 1 0 1 1 1 0 Hom_end-associated Hint SH2_2 PF14633.1 XP_011276589.1 - 8.4e-82 273.5 2.2 8.4e-82 273.5 1.5 1.9 2 0 0 2 2 2 1 SH2 domain YqgF PF14639.1 XP_011276589.1 - 5.7e-41 139.5 0.0 2.5e-40 137.4 0.0 2.2 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.1 XP_011276589.1 - 8e-31 106.2 0.0 2.2e-30 104.8 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif DLD PF14878.1 XP_011276589.1 - 1.3e-29 102.6 0.5 1.3e-29 102.6 0.3 4.8 4 1 1 5 5 5 1 Death-like domain of SPT6 HTH_44 PF14641.1 XP_011276589.1 - 2.7e-25 88.6 3.6 2.7e-25 88.6 2.5 2.9 3 0 0 3 3 3 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.1 XP_011276589.1 - 3.6e-22 78.3 26.8 3.6e-22 78.3 18.5 4.2 3 1 1 4 4 4 1 Acidic N-terminal SPT6 SH2 PF00017.19 XP_011276589.1 - 8.4e-07 28.7 0.0 2.8e-06 27.0 0.0 2.0 1 0 0 1 1 1 1 SH2 domain Frataxin_Cyay PF01491.11 XP_011276591.1 - 6.1e-24 83.9 0.0 1e-23 83.1 0.0 1.4 1 1 0 1 1 1 1 Frataxin-like domain RRM_1 PF00076.17 XP_011276592.1 - 9.9e-13 47.5 0.0 1.8e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 XP_011276592.1 - 1e-05 25.2 0.0 1.7e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 XP_011276592.1 - 1.7e-05 24.6 0.0 3e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF3007 PF11460.3 XP_011276592.1 - 2.5 8.2 5.5 0.2 11.7 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3007) Methyltransf_6 PF03737.10 XP_011276593.1 - 3.4e-28 98.4 0.1 4.2e-28 98.1 0.1 1.1 1 0 0 1 1 1 1 Demethylmenaquinone methyltransferase DnaJ-X PF14308.1 XP_011276594.1 - 2.6e-63 212.9 6.9 2.6e-63 212.9 4.8 3.1 2 1 1 3 3 3 1 X-domain of DnaJ-containing DnaJ PF00226.26 XP_011276594.1 - 7.2e-25 86.5 4.4 3.8e-24 84.2 3.0 2.4 1 0 0 1 1 1 1 DnaJ domain Ndc1_Nup PF09531.5 XP_011276594.1 - 6.8 4.9 7.9 12 4.1 5.5 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TENA_THI-4 PF03070.11 XP_011276595.1 - 7.4e-17 61.7 0.8 9.2e-17 61.4 0.6 1.1 1 0 0 1 1 1 1 TENA/THI-4/PQQC family DUF2779 PF11074.3 XP_011276595.1 - 0.083 12.9 0.4 0.13 12.3 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function(DUF2779) DUF1463 PF07316.6 XP_011276595.1 - 0.089 12.3 0.1 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1463) zf-C2H2 PF00096.21 XP_011276597.1 - 0.03 14.6 0.3 0.084 13.2 0.2 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 XP_011276597.1 - 0.038 14.1 0.1 0.09 12.9 0.1 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 XP_011276597.1 - 0.052 13.8 0.3 0.15 12.4 0.2 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 XP_011276597.1 - 0.11 12.8 1.6 16 6.0 0.0 3.1 3 0 0 3 3 3 0 Zinc-finger double domain zf-BED PF02892.10 XP_011276597.1 - 1.8 8.3 4.3 0.36 10.6 0.2 1.9 2 0 0 2 2 2 0 BED zinc finger Sigma70_ner PF04546.8 XP_011276597.1 - 8.2 5.9 10.9 5.5 6.5 1.4 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region FMO-like PF00743.14 XP_011276598.1 - 4.6e-25 87.8 2.9 8.5e-18 63.8 0.1 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 XP_011276598.1 - 2.6e-23 83.1 0.0 7.5e-23 81.6 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 XP_011276598.1 - 4.3e-12 45.6 0.1 5.6e-10 38.6 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 XP_011276598.1 - 8.7e-09 35.5 0.0 2.9e-08 33.8 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 XP_011276598.1 - 0.00089 19.3 0.0 0.059 13.4 0.0 2.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.1 XP_011276598.1 - 0.0009 19.2 0.0 0.0053 16.7 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 XP_011276598.1 - 0.0012 19.1 0.0 4.6 7.7 0.0 3.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 XP_011276598.1 - 0.23 10.3 0.0 3.4 6.5 0.0 2.3 3 0 0 3 3 3 0 Lycopene cyclase protein Metallophos PF00149.23 XP_011276599.1 - 9e-35 119.8 0.5 1.6e-34 119.0 0.3 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_11 PF13414.1 XP_011276599.1 - 3.8e-23 80.8 5.5 1.1e-18 66.6 0.5 2.9 2 1 1 3 3 3 2 TPR repeat PPP5 PF08321.7 XP_011276599.1 - 2.4e-15 56.3 2.5 3.7e-15 55.7 0.7 2.1 2 0 0 2 2 2 1 PPP5 TPR repeat region TPR_1 PF00515.23 XP_011276599.1 - 5.1e-15 54.3 9.3 1.9e-08 33.5 0.6 4.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 XP_011276599.1 - 7.6e-11 41.0 4.6 1.9e-06 27.3 0.2 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 XP_011276599.1 - 6.4e-08 32.2 4.7 0.0073 16.4 0.0 4.4 5 0 0 5 5 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 XP_011276599.1 - 0.00013 22.5 0.1 0.0025 18.4 0.0 2.3 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 XP_011276599.1 - 0.00088 19.0 0.1 0.082 12.7 0.0 2.3 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 XP_011276599.1 - 0.0052 17.1 1.6 0.046 14.0 0.2 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 XP_011276599.1 - 0.0057 17.1 0.2 0.31 11.7 0.0 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 XP_011276599.1 - 0.014 15.1 7.7 1.5 8.8 0.3 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 XP_011276599.1 - 0.016 15.1 2.7 0.088 12.6 0.8 2.3 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.1 XP_011276599.1 - 0.036 14.0 1.4 0.16 11.9 0.1 2.1 1 1 0 2 2 2 0 Tetratricopeptide repeat Metallophos_2 PF12850.2 XP_011276599.1 - 0.041 13.7 0.0 0.065 13.0 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain TPR_7 PF13176.1 XP_011276599.1 - 0.11 12.2 0.2 0.52 10.2 0.0 2.3 2 0 0 2 2 1 0 Tetratricopeptide repeat MIT PF04212.13 XP_011276599.1 - 0.13 12.1 3.8 0.32 10.9 0.4 2.7 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain PAT1 PF09770.4 XP_011276600.1 - 0.17 10.0 14.7 0.18 9.9 10.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ThiS PF02597.15 XP_011276601.1 - 2e-09 37.7 0.0 2.1e-09 37.6 0.0 1.0 1 0 0 1 1 1 1 ThiS family dsrm PF00035.20 XP_011276602.1 - 4.6e-05 23.8 0.0 0.81 10.3 0.0 3.1 2 0 0 2 2 2 2 Double-stranded RNA binding motif Med26 PF08711.6 XP_011276602.1 - 0.0027 17.1 4.9 2.9 7.4 0.1 4.3 4 1 0 4 4 4 3 TFIIS helical bundle-like domain GCS PF03074.11 XP_011276602.1 - 0.0071 15.4 0.9 0.012 14.7 0.6 1.3 1 0 0 1 1 1 1 Glutamate-cysteine ligase dsrm PF00035.20 XP_011276603.1 - 1.6e-07 31.7 4.2 3.6e-05 24.2 0.0 3.2 3 0 0 3 3 3 2 Double-stranded RNA binding motif dsrm PF00035.20 XP_011276604.1 - 1.1e-12 48.3 4.4 9.5e-05 22.8 0.0 4.4 4 0 0 4 4 4 3 Double-stranded RNA binding motif Ribonuclease_3 PF00636.21 XP_011276604.1 - 0.17 12.3 0.0 0.17 12.3 0.0 3.8 4 1 0 4 4 4 0 Ribonuclease III domain 4HBT PF03061.17 XP_011276605.1 - 1.7e-06 28.0 0.0 2.8e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily DUF1162 PF06650.7 XP_011276606.1 - 9.1e-88 294.0 1.5 4.3e-84 281.9 0.0 3.8 3 1 0 3 3 3 2 Protein of unknown function (DUF1162) Chorein_N PF12624.2 XP_011276606.1 - 1.4e-31 108.4 1.7 7.1e-31 106.1 1.2 2.4 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 XP_011276606.1 - 0.002 18.2 0.0 0.0051 16.9 0.0 1.7 1 0 0 1 1 1 1 ATG C terminal domain Formyl_trans_N PF00551.14 XP_011276607.1 - 4.9e-30 104.4 0.0 7e-30 103.9 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.13 XP_011276607.1 - 9.5e-09 35.2 0.0 1.9e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain MFS_1 PF07690.11 XP_011276608.1 - 6.4e-18 64.5 20.4 5.3e-15 54.9 16.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 XP_011276608.1 - 1e-14 54.3 6.7 1e-14 54.3 4.7 2.5 2 1 1 3 3 3 1 Nodulin-like SAYSvFN PF10260.4 XP_011276608.1 - 0.064 13.0 1.0 0.62 9.8 0.0 2.7 2 0 0 2 2 2 0 Uncharacterized conserved domain (SAYSvFN) SR-25 PF10500.4 XP_011276609.1 - 2.1 7.7 10.3 2.7 7.4 7.1 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Suf PF05843.9 XP_011276610.1 - 0.084 12.5 8.0 0.1 12.2 5.6 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Med13_C PF06333.7 XP_011276610.1 - 0.24 9.9 9.2 0.27 9.7 6.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal Pox_A12 PF04651.8 XP_011276610.1 - 0.8 9.8 8.3 1.4 8.9 5.7 1.4 1 1 0 1 1 1 0 Poxvirus A12 protein AUX_IAA PF02309.11 XP_011276610.1 - 1.3 8.7 6.7 1.6 8.4 4.7 1.2 1 0 0 1 1 1 0 AUX/IAA family Dicty_REP PF05086.7 XP_011276610.1 - 2.5 5.7 11.9 2.6 5.6 8.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein HD-ZIP_N PF04618.7 XP_011276610.1 - 7.6 7.1 11.0 5.1 7.6 6.1 1.8 2 1 0 2 2 2 0 HD-ZIP protein N terminus NST1 PF13945.1 XP_011276610.1 - 9.4 6.2 10.7 13 5.7 7.4 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator Glyco_hydro_63 PF03200.11 XP_011276611.1 - 9.9e-240 797.6 6.0 1.8e-238 793.4 4.1 1.9 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Trehalase PF01204.13 XP_011276611.1 - 1.3e-06 27.3 0.8 2.2e-06 26.6 0.5 1.3 1 0 0 1 1 1 1 Trehalase GDE_C PF06202.9 XP_011276611.1 - 0.0012 17.6 0.0 0.0027 16.5 0.0 1.6 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Bac_rhamnosid PF05592.6 XP_011276611.1 - 0.0013 17.0 0.0 0.0022 16.3 0.0 1.2 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase Spiralin PF05215.8 XP_011276611.1 - 0.23 10.5 0.0 10 5.1 0.0 2.2 2 0 0 2 2 2 0 Spiralin TBPIP PF07106.8 XP_011276612.1 - 4.3e-28 97.9 9.1 3.5e-27 95.0 6.3 1.9 1 1 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) EAP30 PF04157.11 XP_011276612.1 - 6.4e-05 22.2 1.6 0.018 14.1 0.0 2.2 2 0 0 2 2 2 2 EAP30/Vps36 family Syntaxin_2 PF14523.1 XP_011276612.1 - 0.015 15.3 3.3 0.015 15.3 2.3 1.9 2 0 0 2 2 2 0 Syntaxin-like protein HTH_IclR PF09339.5 XP_011276612.1 - 0.018 14.6 0.0 0.033 13.7 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain DUF2120 PF09893.4 XP_011276612.1 - 0.021 14.7 0.9 0.036 14.0 0.3 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) Cas_Csa5 PF09702.5 XP_011276612.1 - 0.022 14.8 0.4 0.053 13.6 0.1 1.7 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csa5) Uds1 PF15456.1 XP_011276612.1 - 0.042 13.8 0.6 0.082 12.8 0.4 1.4 1 0 0 1 1 1 0 Up-regulated During Septation GPP34 PF05719.6 XP_011276612.1 - 0.077 13.0 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Golgi phosphoprotein 3 (GPP34) Allexi_40kDa PF05549.6 XP_011276612.1 - 0.098 11.9 1.9 0.12 11.6 1.3 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein Vac_Fusion PF02346.11 XP_011276612.1 - 0.15 11.5 0.9 0.4 10.1 0.1 2.0 2 0 0 2 2 2 0 Chordopoxvirus fusion protein Trans_reg_C PF00486.23 XP_011276612.1 - 0.15 11.9 0.4 1.1 9.2 0.1 2.1 1 1 1 2 2 2 0 Transcriptional regulatory protein, C terminal Mnd1 PF03962.10 XP_011276612.1 - 0.16 11.6 3.0 1.2 8.7 2.1 2.0 1 1 0 1 1 1 0 Mnd1 family DUF1542 PF07564.6 XP_011276612.1 - 0.17 11.9 2.5 0.39 10.7 1.7 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) TMP_2 PF06791.8 XP_011276612.1 - 0.19 11.2 2.7 0.65 9.5 0.2 2.1 1 1 0 2 2 2 0 Prophage tail length tape measure protein Fib_alpha PF08702.5 XP_011276612.1 - 0.84 9.7 6.8 0.89 9.6 4.0 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family TMF_DNA_bd PF12329.3 XP_011276612.1 - 1.8 8.4 6.1 0.68 9.7 0.5 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF605 PF04652.11 XP_011276613.1 - 0.00011 21.8 26.0 0.00014 21.3 18.0 1.3 1 0 0 1 1 1 1 Vta1 like Macoilin PF09726.4 XP_011276613.1 - 0.15 10.2 29.9 0.21 9.8 20.7 1.1 1 0 0 1 1 1 0 Transmembrane protein Peptidase_S64 PF08192.6 XP_011276613.1 - 2 6.6 20.1 2.9 6.1 13.9 1.1 1 0 0 1 1 1 0 Peptidase family S64 Daxx PF03344.10 XP_011276613.1 - 7.7 4.8 21.9 11 4.3 15.2 1.1 1 0 0 1 1 1 0 Daxx Family OTU PF02338.14 XP_011276614.1 - 2.2e-20 73.4 0.6 7.1e-20 71.7 0.0 2.0 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 XP_011276614.1 - 0.00038 19.8 1.6 0.024 13.9 0.0 2.6 1 1 1 2 2 2 2 Peptidase C65 Otubain Plasmodium_Vir PF05795.6 XP_011276614.1 - 0.069 12.3 5.5 0.088 11.9 3.8 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein eIF3_subunit PF08597.5 XP_011276614.1 - 1.2 8.6 20.1 2 7.9 14.0 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Nop53 PF07767.6 XP_011276614.1 - 4.8 6.0 25.7 7.2 5.4 17.8 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) GAGA_bind PF06217.7 XP_011276614.1 - 5.5 6.8 10.0 7.9 6.3 7.0 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family YchF-GTPase_C PF06071.8 XP_011276615.1 - 1.1e-23 82.8 0.3 2.6e-23 81.6 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 XP_011276615.1 - 1.4e-15 57.2 0.4 5.7e-15 55.2 0.2 2.2 1 1 1 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.16 XP_011276615.1 - 9.1e-06 25.4 0.0 2.2e-05 24.1 0.0 1.7 1 1 0 1 1 1 1 TGS domain 2-Hacid_dh_C PF02826.14 XP_011276615.1 - 8.7e-05 21.7 0.0 0.21 10.7 0.1 2.4 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FeoB_N PF02421.13 XP_011276615.1 - 0.0017 17.6 0.0 0.0036 16.5 0.0 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B HAUS-augmin3 PF14932.1 XP_011276615.1 - 0.0027 16.9 0.1 0.005 16.0 0.1 1.4 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 LigB PF02900.13 XP_011276615.1 - 0.047 12.6 0.0 0.078 11.9 0.0 1.3 1 0 0 1 1 1 0 Catalytic LigB subunit of aromatic ring-opening dioxygenase AAA_14 PF13173.1 XP_011276615.1 - 0.068 13.0 0.1 0.4 10.5 0.0 2.3 2 1 0 2 2 2 0 AAA domain Miro PF08477.8 XP_011276615.1 - 0.13 12.7 1.8 13 6.3 0.0 2.9 3 0 0 3 3 3 0 Miro-like protein AAA_23 PF13476.1 XP_011276615.1 - 0.26 11.5 9.7 14 5.9 6.7 2.5 1 1 0 1 1 1 0 AAA domain CBFD_NFYB_HMF PF00808.18 XP_011276616.1 - 5.1e-15 55.2 0.4 6.3e-15 54.9 0.3 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 XP_011276616.1 - 1.7e-06 28.0 0.1 2e-06 27.8 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PCP_red PF08369.5 XP_011276616.1 - 0.024 14.4 0.4 0.04 13.7 0.3 1.4 1 0 0 1 1 1 0 Proto-chlorophyllide reductase 57 kD subunit CN_hydrolase PF00795.17 XP_011276617.1 - 4.6e-31 107.6 0.0 7.5e-31 106.9 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase SBBP PF06739.6 XP_011276617.1 - 0.012 15.3 1.2 6.1 6.7 0.4 3.1 3 0 0 3 3 3 0 Beta-propeller repeat RNase_T PF00929.19 XP_011276618.1 - 3e-05 24.3 0.3 0.0087 16.3 0.0 2.3 1 1 1 2 2 2 2 Exonuclease DUF89 PF01937.14 XP_011276618.1 - 0.0062 15.3 0.0 0.0074 15.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF89 DUF977 PF06163.6 XP_011276618.1 - 0.018 14.7 0.0 0.076 12.7 0.0 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF977) Cna_B PF05738.8 XP_011276618.1 - 0.051 13.3 0.1 0.27 10.9 0.0 2.2 2 0 0 2 2 2 0 Cna protein B-type domain FGGY_C PF02782.11 XP_011276619.1 - 2.2e-52 177.5 0.1 4e-52 176.7 0.1 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 XP_011276619.1 - 6e-25 87.9 0.0 2.1e-24 86.2 0.0 1.9 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 XP_011276619.1 - 0.0028 16.9 0.0 0.19 10.9 0.0 2.4 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family Rax2 PF12768.2 XP_011276620.1 - 8.5e-72 241.7 41.1 2.9e-69 233.3 2.2 5.4 3 2 1 5 5 5 4 Cortical protein marker for cell polarity TRAPPC-Trs85 PF12739.2 XP_011276621.1 - 9e-99 330.9 0.1 1.2e-98 330.4 0.1 1.1 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit EMP70 PF02990.11 XP_011276622.1 - 1.3e-200 667.3 8.0 1.7e-200 666.9 5.6 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 zf-CCHC PF00098.18 XP_011276623.1 - 8.4e-15 53.8 31.7 1.3e-06 28.0 0.9 4.3 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_4 PF14392.1 XP_011276623.1 - 0.00014 21.4 22.5 0.0085 15.7 0.8 4.4 4 0 0 4 4 4 3 Zinc knuckle zf-CCHC_6 PF15288.1 XP_011276623.1 - 1.3 8.7 21.2 7.7 6.2 0.1 4.4 3 1 1 4 4 4 0 Zinc knuckle Rad51 PF08423.6 XP_011276624.1 - 2.7e-34 118.2 0.0 1.7e-21 76.2 0.0 2.0 1 1 1 2 2 2 2 Rad51 Serinc PF03348.10 XP_011276625.1 - 9.9e-151 502.2 16.0 1.1e-150 502.0 11.1 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) TMEM173 PF15009.1 XP_011276625.1 - 0.9 8.2 3.3 2 7.1 1.9 1.8 1 1 0 1 1 1 0 Transmembrane protein 173 Actin PF00022.14 XP_011276626.1 - 4.8e-28 97.6 0.0 1e-18 66.9 0.0 2.1 2 0 0 2 2 2 2 Actin OMP_b-brl_2 PF13568.1 XP_011276626.1 - 0.055 13.2 0.0 0.09 12.5 0.0 1.3 1 0 0 1 1 1 0 Outer membrane protein beta-barrel domain CDC37_N PF03234.9 XP_011276627.1 - 6.3e-56 189.4 14.2 6.3e-56 189.4 9.8 3.5 2 1 2 4 4 4 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 XP_011276627.1 - 9.8e-28 96.7 12.5 9.8e-28 96.7 8.7 2.5 3 1 0 3 3 3 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 XP_011276627.1 - 1.5e-24 85.7 3.5 1.5e-24 85.7 2.5 3.1 3 0 0 3 3 3 1 Cdc37 C terminal domain DUF2415 PF10313.4 XP_011276628.1 - 1.1e-18 66.6 0.2 2.1e-18 65.6 0.2 1.5 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) WD40 PF00400.27 XP_011276628.1 - 0.044 13.6 2.7 7 6.6 0.2 3.2 3 0 0 3 3 3 0 WD domain, G-beta repeat FMO-like PF00743.14 XP_011276629.1 - 8.1e-40 136.5 1.9 1.4e-22 79.6 1.0 3.0 1 1 2 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 XP_011276629.1 - 7.4e-22 78.4 0.2 6.8e-21 75.2 0.1 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 XP_011276629.1 - 7.5e-12 45.5 0.0 7.3e-10 39.0 0.0 2.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 XP_011276629.1 - 2.7e-11 43.4 0.0 1e-10 41.6 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 XP_011276629.1 - 1.1e-08 34.4 0.5 7.6e-08 31.6 0.0 2.3 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 XP_011276629.1 - 2.4e-07 31.0 0.9 0.064 13.6 0.0 3.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 XP_011276629.1 - 3.2e-06 25.8 0.1 7.1e-05 21.4 0.0 2.4 1 1 2 3 3 3 1 HI0933-like protein NAD_binding_8 PF13450.1 XP_011276629.1 - 3.5e-06 26.9 0.0 8.3e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 XP_011276629.1 - 4.8e-05 22.5 0.1 0.061 12.4 0.0 2.3 2 0 0 2 2 2 2 Thi4 family DAO PF01266.19 XP_011276629.1 - 0.00019 20.4 0.0 0.076 11.9 0.0 3.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.18 XP_011276629.1 - 0.013 15.2 0.1 0.18 11.4 0.0 2.6 3 0 0 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Spore_II_R PF09551.5 XP_011276629.1 - 0.014 15.3 0.9 0.3 11.1 0.1 2.3 2 0 0 2 2 2 0 Stage II sporulation protein R (spore_II_R) FAD_binding_2 PF00890.19 XP_011276629.1 - 0.02 13.7 0.0 1.2 7.9 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Sec15 PF04091.7 XP_011276629.1 - 0.047 13.0 0.5 0.092 12.0 0.1 1.6 2 0 0 2 2 2 0 Exocyst complex subunit Sec15-like ThiF PF00899.16 XP_011276629.1 - 0.065 13.0 0.9 1.3 8.8 0.0 3.0 2 1 1 3 3 3 0 ThiF family FAD_binding_3 PF01494.14 XP_011276629.1 - 0.077 12.0 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.2 XP_011276629.1 - 0.14 11.1 0.0 0.26 10.3 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Fungal_trans PF04082.13 XP_011276630.1 - 9.8e-25 86.8 1.0 9.8e-25 86.8 0.7 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 XP_011276630.1 - 1.9e-07 30.8 14.6 3.1e-07 30.2 10.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RNA_pol_Rpb1_5 PF04998.12 XP_011276631.1 - 2.3e-95 319.0 0.1 3.2e-95 318.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 XP_011276631.1 - 2e-82 277.1 0.1 3.7e-82 276.2 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 XP_011276631.1 - 1.6e-69 233.0 0.0 3.4e-69 232.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 XP_011276631.1 - 2.3e-39 134.6 0.0 6.2e-39 133.2 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 XP_011276631.1 - 6.2e-31 106.3 0.0 1.8e-30 104.8 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Apc13p PF05839.6 XP_011276632.1 - 1.4e-10 40.9 4.9 1.8e-10 40.6 0.2 2.2 1 1 1 2 2 2 1 Apc13p protein Imm6 PF14434.1 XP_011276632.1 - 0.047 13.4 0.4 0.074 12.7 0.2 1.3 1 0 0 1 1 1 0 Immunity protein Imm6 Eaf7 PF07904.8 XP_011276632.1 - 0.43 10.5 3.7 0.85 9.6 2.5 1.7 1 1 0 1 1 1 0 Chromatin modification-related protein EAF7 DUF4048 PF13257.1 XP_011276632.1 - 0.46 10.0 5.5 0.44 10.1 1.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4048) Memo PF01875.12 XP_011276633.1 - 8.9e-76 254.3 0.0 1e-75 254.1 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein THUMP PF02926.12 XP_011276633.1 - 0.082 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 THUMP domain Lipase_3 PF01764.20 XP_011276634.1 - 1.4e-30 105.7 0.0 2e-30 105.2 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Esterase PF00756.15 XP_011276634.1 - 0.012 15.0 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Abhydrolase_5 PF12695.2 XP_011276634.1 - 0.021 14.5 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.8 XP_011276634.1 - 0.025 14.1 0.0 0.047 13.2 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_6 PF12697.2 XP_011276634.1 - 0.029 14.2 0.0 0.037 13.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family MatE PF01554.13 XP_011276635.1 - 2.2e-63 212.7 35.8 4.7e-34 117.3 6.8 2.7 3 0 0 3 3 3 2 MatE Fasciclin PF02469.17 XP_011276636.1 - 3.3e-08 33.5 0.0 4.5e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Fasciclin domain Adaptin_N PF01602.15 XP_011276637.1 - 1.9e-104 349.9 10.7 2.2e-104 349.6 7.4 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 XP_011276637.1 - 1.6e-10 41.1 4.8 1.1e-08 35.1 1.0 2.5 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 XP_011276637.1 - 2.1e-09 37.5 3.9 0.0004 20.6 0.2 4.0 2 2 3 5 5 5 3 HEAT repeats HEAT PF02985.17 XP_011276637.1 - 0.0012 18.7 1.5 6.6 7.0 0.0 4.9 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 XP_011276637.1 - 0.0023 18.3 0.8 2.5 8.7 0.0 3.6 3 1 1 4 4 4 2 HEAT-like repeat ENTH PF01417.15 XP_011276637.1 - 0.01 15.7 0.4 2.7 7.8 0.0 2.6 2 0 0 2 2 2 0 ENTH domain T_hemolysin PF12261.3 XP_011276637.1 - 0.051 13.1 0.0 0.15 11.5 0.0 1.7 1 1 1 2 2 2 0 Thermostable hemolysin DEAD PF00270.24 XP_011276638.1 - 1.3e-25 89.8 0.0 4.3e-25 88.1 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF1998 PF09369.5 XP_011276638.1 - 1.4e-12 47.9 0.1 3.4e-12 46.7 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.26 XP_011276638.1 - 5.1e-12 45.4 0.1 3.5e-11 42.8 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain CDT1 PF08839.6 XP_011276638.1 - 0.0015 18.4 0.9 0.0015 18.4 0.6 2.1 2 0 0 2 2 2 1 DNA replication factor CDT1 like Response_reg PF00072.19 XP_011276639.1 - 1.4e-21 76.6 0.1 4e-13 49.3 0.0 2.8 3 0 0 3 3 3 2 Response regulator receiver domain CMS1 PF14617.1 XP_011276640.1 - 3.5e-07 29.5 15.3 2.8e-05 23.3 10.6 2.7 1 1 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit AF-4 PF05110.8 XP_011276640.1 - 0.056 11.3 6.6 0.07 11.0 4.6 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF913 PF06025.7 XP_011276640.1 - 0.075 11.7 2.3 0.11 11.1 1.6 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) MFS_1 PF07690.11 XP_011276641.1 - 1.8e-39 135.4 48.8 3.7e-34 118.0 18.0 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 XP_011276641.1 - 6.8e-12 44.7 22.3 1.4e-11 43.7 15.5 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.2 XP_011276641.1 - 0.0034 17.1 2.9 0.0034 17.1 2.0 2.7 2 0 0 2 2 2 1 MFS_1 like family DAO PF01266.19 XP_011276642.1 - 2.4e-19 69.4 0.0 4.9e-19 68.4 0.0 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase AA_permease PF00324.16 XP_011276643.1 - 1.4e-79 267.7 48.2 1.6e-79 267.4 33.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 XP_011276643.1 - 1.1e-27 96.6 55.2 1.5e-27 96.2 38.3 1.0 1 0 0 1 1 1 1 Amino acid permease Plus-3 PF03126.13 XP_011276645.1 - 0.012 15.6 0.3 0.033 14.2 0.1 1.8 2 0 0 2 2 2 0 Plus-3 domain FMO-like PF00743.14 XP_011276646.1 - 2.2e-29 102.0 0.0 8.3e-13 47.3 0.0 3.1 2 1 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 XP_011276646.1 - 2.1e-16 60.5 0.0 4.1e-15 56.3 0.0 2.7 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 XP_011276646.1 - 2.6e-09 37.0 0.1 6.9e-08 32.4 0.1 2.8 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 XP_011276646.1 - 2.1e-07 30.8 0.0 5.4e-06 26.3 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 XP_011276646.1 - 4.8e-06 26.5 0.0 0.00013 21.9 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 XP_011276646.1 - 0.00019 20.6 0.0 0.0013 17.9 0.0 2.0 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.1 XP_011276646.1 - 0.00021 20.2 0.0 0.25 10.2 0.0 2.7 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 XP_011276646.1 - 0.0016 18.8 0.3 2.7 8.4 0.0 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Semialdhyde_dh PF01118.19 XP_011276646.1 - 0.0048 17.2 0.0 0.097 12.9 0.0 2.8 3 0 0 3 3 3 1 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 XP_011276646.1 - 0.016 15.2 0.1 0.82 9.7 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase OCD_Mu_crystall PF02423.10 XP_011276646.1 - 0.095 11.4 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family HI0933_like PF03486.9 XP_011276646.1 - 0.19 10.1 0.2 0.39 9.1 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein F-box-like PF12937.2 XP_011276649.1 - 0.088 12.5 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 F-box-like Peptidase_M9 PF01752.12 XP_011276650.1 - 0.044 12.6 1.4 0.051 12.4 1.0 1.1 1 0 0 1 1 1 0 Collagenase DUF4446 PF14584.1 XP_011276650.1 - 0.11 12.2 0.2 0.23 11.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) tRNA-synt_2c PF01411.14 XP_011276651.1 - 1.2e-220 733.4 0.3 2.6e-220 732.4 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 XP_011276651.1 - 1.5e-18 66.3 0.1 3.9e-18 65.0 0.1 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 XP_011276651.1 - 1.9e-05 24.2 3.3 5.3e-05 22.8 2.3 1.9 1 0 0 1 1 1 1 DHHA1 domain SUR7 PF06687.7 XP_011276652.1 - 3.3e-09 36.6 11.2 4.8e-09 36.0 7.8 1.2 1 0 0 1 1 1 1 SUR7/PalI family MFS_1 PF07690.11 XP_011276653.1 - 1.6e-29 102.7 18.6 2.7e-29 101.9 12.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.11 XP_011276654.1 - 2.9e-31 108.4 19.4 3.7e-31 108.1 13.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily YwiC PF14256.1 XP_011276654.1 - 0.027 14.5 12.0 0.73 9.9 1.8 2.8 2 0 0 2 2 2 0 YwiC-like protein DUF4064 PF13273.1 XP_011276654.1 - 4.3 7.4 10.5 2.4 8.2 2.1 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF4064) DLH PF01738.13 XP_011276655.1 - 4.7e-31 107.7 0.0 5.7e-31 107.4 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 XP_011276655.1 - 4.2e-08 33.0 0.0 5.8e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PAF-AH_p_II PF03403.8 XP_011276655.1 - 0.032 12.5 0.0 0.041 12.1 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II YccJ PF13993.1 XP_011276655.1 - 0.048 13.7 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 YccJ-like protein Abhydrolase_2 PF02230.11 XP_011276655.1 - 0.092 12.1 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Methyltransf_11 PF08241.7 XP_011276656.1 - 0.0031 17.9 0.0 0.007 16.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain HXXSHH PF07586.6 XP_011276656.1 - 0.054 12.4 1.1 0.086 11.7 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) AAA_2 PF07724.9 XP_011276657.1 - 4.7e-37 127.5 0.7 4.7e-37 127.5 0.5 2.2 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 XP_011276657.1 - 2.1e-14 53.8 0.1 5.5e-14 52.5 0.1 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 XP_011276657.1 - 1e-08 34.9 0.1 3.5e-08 33.2 0.0 2.0 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 XP_011276657.1 - 1.3e-07 31.4 0.1 3.9e-07 29.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 XP_011276657.1 - 2.5e-05 24.4 0.1 0.00055 20.0 0.1 2.8 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 XP_011276657.1 - 5.1e-05 22.8 0.0 0.032 13.7 0.0 2.7 3 0 0 3 3 3 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 XP_011276657.1 - 7.3e-05 22.0 0.0 0.0027 16.9 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 XP_011276657.1 - 0.00011 22.9 1.0 0.00043 21.0 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 XP_011276657.1 - 0.00013 22.0 0.1 0.00058 19.8 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain Sigma54_activ_2 PF14532.1 XP_011276657.1 - 0.00045 20.2 0.0 0.0025 17.8 0.0 2.2 2 1 0 2 2 2 1 Sigma-54 interaction domain IstB_IS21 PF01695.12 XP_011276657.1 - 0.0012 18.3 0.0 0.0025 17.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 XP_011276657.1 - 0.0019 18.1 1.5 0.0043 16.9 0.1 2.3 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 XP_011276657.1 - 0.0037 16.3 0.0 0.012 14.6 0.0 1.9 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_29 PF13555.1 XP_011276657.1 - 0.0097 15.4 0.0 0.022 14.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_19 PF13245.1 XP_011276657.1 - 0.0099 15.6 0.0 0.021 14.5 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain ABC_tran PF00005.22 XP_011276657.1 - 0.012 15.8 0.9 0.012 15.8 0.6 2.3 2 1 0 2 2 2 0 ABC transporter SKI PF01202.17 XP_011276657.1 - 0.022 14.6 0.5 0.18 11.6 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase Kinase-PPPase PF03618.9 XP_011276657.1 - 0.035 13.6 1.5 0.042 13.3 0.1 1.8 2 0 0 2 2 2 0 Kinase/pyrophosphorylase AAA_33 PF13671.1 XP_011276657.1 - 0.038 13.8 0.4 0.12 12.2 0.1 2.1 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.1 XP_011276657.1 - 0.063 13.5 0.5 0.063 13.5 0.4 2.7 2 1 0 2 2 2 0 AAA domain NACHT PF05729.7 XP_011276657.1 - 0.1 12.2 0.1 0.93 9.1 0.0 2.4 3 0 0 3 3 3 0 NACHT domain G-alpha PF00503.15 XP_011276657.1 - 1 7.9 14.9 6.9 5.2 9.9 2.3 1 1 1 2 2 2 0 G-protein alpha subunit UDP-g_GGTase PF06427.6 XP_011276658.1 - 1.7e-47 161.4 0.5 3.5e-47 160.4 0.3 1.6 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 XP_011276658.1 - 6.2e-08 32.2 3.4 6.8e-08 32.1 0.1 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 8 Glyco_hydro_42C PF08533.5 XP_011276658.1 - 0.0057 16.1 0.3 0.031 13.7 0.0 2.3 2 0 0 2 2 2 1 Beta-galactosidase C-terminal domain MTHFR PF02219.12 XP_011276659.1 - 4.7e-118 393.4 0.0 6.6e-118 392.9 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase MFS_1 PF07690.11 XP_011276660.1 - 2.9e-28 98.6 19.6 3e-16 59.0 2.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 XP_011276660.1 - 3.7e-07 28.9 26.1 3.1e-06 25.8 9.2 2.7 1 1 1 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.2 XP_011276660.1 - 0.003 17.3 1.0 0.003 17.3 0.7 3.7 3 2 0 3 3 3 1 MFS_1 like family Spore_YhaL PF14147.1 XP_011276660.1 - 0.88 9.0 4.5 2.1 7.8 0.2 2.7 2 0 0 2 2 2 0 Sporulation protein YhaL Arrestin_C PF02752.17 XP_011276661.1 - 7.6e-06 26.0 2.4 1.5e-05 25.0 0.5 2.2 3 0 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain DnaJ PF00226.26 XP_011276662.1 - 2.2e-27 94.5 1.4 3.7e-27 93.8 0.9 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 XP_011276662.1 - 1e-21 76.5 2.2 6.9e-19 67.5 0.1 2.4 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 XP_011276662.1 - 4.5e-13 49.0 16.4 7.2e-13 48.3 11.4 1.3 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 XP_011276662.1 - 0.003 17.2 5.0 0.61 9.7 0.6 2.5 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family MFS_1 PF07690.11 XP_011276663.1 - 3e-39 134.7 30.7 3e-39 134.7 21.3 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Zn_clus PF00172.13 XP_011276665.1 - 1.5e-05 24.8 8.6 2.7e-05 23.9 6.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DivIC PF04977.10 XP_011276665.1 - 0.049 13.1 0.1 0.14 11.6 0.0 1.8 1 0 0 1 1 1 0 Septum formation initiator HALZ PF02183.13 XP_011276665.1 - 0.098 12.3 3.7 0.58 9.9 1.6 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper Gp_dh_C PF02800.15 XP_011276666.1 - 5.7e-67 224.0 0.0 1e-66 223.2 0.0 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 XP_011276666.1 - 1.4e-60 203.6 0.0 2.1e-60 203.0 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 XP_011276666.1 - 0.011 14.9 0.0 0.023 13.8 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Poty_coat PF00767.13 XP_011276666.1 - 0.019 14.2 0.0 0.028 13.7 0.0 1.2 1 0 0 1 1 1 0 Potyvirus coat protein TrkA_N PF02254.13 XP_011276666.1 - 0.032 14.2 0.1 0.44 10.5 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain DapB_N PF01113.15 XP_011276666.1 - 0.034 14.0 0.0 0.13 12.1 0.0 2.0 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.14 XP_011276667.1 - 3.8e-41 140.1 0.0 8.2e-41 139.0 0.0 1.6 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 XP_011276667.1 - 2.1e-11 43.9 0.0 4.9e-11 42.7 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh PF00389.25 XP_011276667.1 - 1.4e-09 37.5 0.0 1.7e-09 37.2 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain IlvN PF07991.7 XP_011276667.1 - 4.9e-06 26.0 0.0 7.9e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 XP_011276667.1 - 8e-05 23.0 0.0 0.00015 22.1 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.17 XP_011276667.1 - 0.00017 22.1 0.0 0.00034 21.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold CoA_binding PF02629.14 XP_011276667.1 - 0.013 16.0 0.0 0.024 15.1 0.0 1.4 1 0 0 1 1 1 0 CoA binding domain AdoHcyase_NAD PF00670.16 XP_011276667.1 - 0.026 14.3 0.1 0.042 13.7 0.0 1.2 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ApbA PF02558.11 XP_011276667.1 - 0.057 12.8 0.0 0.16 11.4 0.0 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_binding_10 PF13460.1 XP_011276667.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding COX5B PF01215.14 XP_011276668.1 - 7.8e-52 174.5 0.0 9.1e-52 174.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb Ribosomal_S26e PF01283.14 XP_011276669.1 - 2.7e-51 172.5 9.1 3.3e-51 172.3 6.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Fer4_7 PF12838.2 XP_011276669.1 - 0.04 14.3 0.7 0.22 11.9 0.2 2.0 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_10 PF13237.1 XP_011276669.1 - 0.069 12.9 0.8 0.069 12.9 0.6 1.8 1 1 1 2 2 2 0 4Fe-4S dicluster domain NosL PF05573.7 XP_011276670.1 - 0.053 13.2 0.1 0.089 12.4 0.1 1.3 1 0 0 1 1 1 0 NosL HMG_box PF00505.14 XP_011276670.1 - 2.4 8.4 5.3 13 6.1 0.4 2.4 1 1 1 2 2 2 0 HMG (high mobility group) box MFS_1 PF07690.11 XP_011276671.1 - 2e-39 135.3 32.2 2e-39 135.3 22.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 XP_011276671.1 - 2.6e-09 36.2 10.0 2.6e-09 36.2 6.9 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter Zip PF02535.17 XP_011276672.1 - 2e-60 204.4 6.2 2.3e-60 204.2 4.3 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter DUF2207 PF09972.4 XP_011276672.1 - 0.0097 14.5 0.0 0.28 9.7 0.0 2.1 2 0 0 2 2 2 1 Predicted membrane protein (DUF2207) YniB PF14002.1 XP_011276672.1 - 0.046 13.1 0.5 0.046 13.1 0.3 1.8 2 0 0 2 2 2 0 YniB-like protein Claudin_2 PF13903.1 XP_011276672.1 - 0.15 11.7 13.4 6.6 6.3 1.9 3.3 2 1 1 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction ICE2 PF08426.5 XP_011276673.1 - 5.6e-146 486.3 34.9 7.6e-146 485.9 24.2 1.2 1 0 0 1 1 1 1 ICE2 Myb_DNA-bind_6 PF13921.1 XP_011276674.1 - 1.6e-13 50.5 0.6 5.9e-12 45.5 0.1 2.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 XP_011276674.1 - 6.8e-07 29.2 3.9 9.8e-07 28.7 0.3 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain HTH_AsnC-type PF13404.1 XP_011276674.1 - 0.048 13.2 0.2 0.13 11.8 0.0 1.8 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain DUF948 PF06103.6 XP_011276675.1 - 0.04 13.7 20.1 0.58 10.0 1.0 3.9 1 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) ApoO PF09769.4 XP_011276675.1 - 1.8 8.2 6.4 19 4.8 2.8 2.8 1 1 1 2 2 2 0 Apolipoprotein O ATG_C PF09333.6 XP_011276675.1 - 2.5 8.2 10.7 8.5 6.6 0.3 3.3 1 1 0 2 2 2 0 ATG C terminal domain Asp-B-Hydro_N PF05279.6 XP_011276675.1 - 2.7 7.7 24.9 3.8 7.3 17.2 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF883 PF05957.8 XP_011276675.1 - 3.1 8.2 21.2 16 5.9 3.1 4.0 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF883) V_ATPase_I PF01496.14 XP_011276675.1 - 4.5 4.9 10.6 9.5 3.9 7.4 1.6 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family ATP-synt_B PF00430.13 XP_011276675.1 - 5.7 6.7 30.8 0.63 9.8 8.0 3.4 1 1 2 3 3 3 0 ATP synthase B/B' CF(0) tRNA-synt_2b PF00587.20 XP_011276676.1 - 2.7e-31 108.4 0.0 5e-31 107.5 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 XP_011276676.1 - 0.028 14.3 0.0 0.099 12.5 0.0 1.9 1 0 0 1 1 1 0 Anticodon binding domain tRNA-synt_2 PF00152.15 XP_011276676.1 - 0.05 12.3 0.2 0.18 10.5 0.0 1.8 2 1 0 2 2 2 0 tRNA synthetases class II (D, K and N) zf-RING_3 PF14369.1 XP_011276676.1 - 0.14 12.1 1.3 0.24 11.4 0.1 1.9 2 0 0 2 2 2 0 zinc-finger Sec61_beta PF03911.11 XP_011276677.1 - 1e-19 70.0 0.6 1.2e-19 69.7 0.4 1.1 1 0 0 1 1 1 1 Sec61beta family RRM_6 PF14259.1 XP_011276678.1 - 3.9e-07 29.9 0.0 8e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 XP_011276678.1 - 1.4e-06 27.7 0.1 3.4e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 XP_011276678.1 - 0.0053 16.5 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MOZ_SAS PF01853.13 XP_011276680.1 - 1.4e-76 255.9 2.6 2.3e-76 255.2 1.8 1.3 1 0 0 1 1 1 1 MOZ/SAS family bZIP_2 PF07716.10 XP_011276681.1 - 0.014 15.1 1.1 0.014 15.1 0.8 4.8 4 1 1 5 5 5 0 Basic region leucine zipper PUB PF09409.5 XP_011276681.1 - 0.055 13.2 0.2 0.055 13.2 0.1 3.6 3 1 1 4 4 4 0 PUB domain IncA PF04156.9 XP_011276681.1 - 1.6 8.2 26.6 0.051 13.1 7.3 3.1 3 0 0 3 3 3 0 IncA protein Peroxin-13_N PF04088.8 XP_011276682.1 - 2.4e-59 199.8 0.9 3.9e-59 199.1 0.6 1.3 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_9 PF14604.1 XP_011276682.1 - 7.1e-12 44.7 0.0 1.2e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 XP_011276682.1 - 1.8e-10 40.0 0.0 3e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 XP_011276682.1 - 4.2e-09 35.7 0.0 7.5e-09 34.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 XP_011276682.1 - 6e-05 23.1 0.0 0.00012 22.2 0.0 1.4 1 0 0 1 1 1 1 Bacterial SH3 domain zf-MIZ PF02891.15 XP_011276683.1 - 1.9e-07 30.5 3.2 1.1e-06 28.0 0.6 2.2 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 XP_011276683.1 - 0.0068 15.8 2.7 0.019 14.4 0.1 2.6 2 1 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit FLO_LFY PF01698.11 XP_011276683.1 - 0.067 12.0 5.7 0.023 13.5 2.3 1.4 2 0 0 2 2 2 0 Floricaula / Leafy protein zf-RING_5 PF14634.1 XP_011276683.1 - 0.11 12.2 1.5 6.7 6.5 0.2 2.4 2 0 0 2 2 2 0 zinc-RING finger domain Nucleo_P87 PF07267.6 XP_011276683.1 - 0.18 10.4 12.5 0.22 10.1 8.3 1.4 1 1 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CDC45 PF02724.9 XP_011276683.1 - 8.2 4.3 13.2 12 3.8 9.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Alpha-amylase PF00128.19 XP_011276684.1 - 1.8e-98 329.8 6.8 1.8e-98 329.8 4.7 1.7 1 1 0 2 2 2 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 XP_011276684.1 - 0.00033 19.7 0.4 0.012 14.5 0.1 2.2 2 0 0 2 2 2 2 glucanotransferase domain of human glycogen debranching enzyme Mito_carr PF00153.22 XP_011276685.1 - 2.4e-42 142.5 4.9 2e-16 59.4 0.0 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein Metallophos PF00149.23 XP_011276686.1 - 6.9e-41 139.8 0.4 9e-41 139.4 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase OHCU_decarbox PF09349.5 XP_011276687.1 - 3.2e-36 125.0 0.0 3.7e-36 124.8 0.0 1.0 1 0 0 1 1 1 1 OHCU decarboxylase Ada3 PF10198.4 XP_011276687.1 - 0.06 13.1 0.4 0.1 12.3 0.2 1.4 1 1 0 1 1 1 0 Histone acetyltransferases subunit 3 Glyco_trans_1_4 PF13692.1 XP_011276687.1 - 0.081 13.0 0.0 0.22 11.6 0.0 1.6 2 0 0 2 2 2 0 Glycosyl transferases group 1 Rho_GDI PF02115.12 XP_011276688.1 - 8.3e-63 211.4 0.9 9e-63 211.3 0.6 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor R3H PF01424.17 XP_011276689.1 - 5.6e-11 41.9 0.0 1e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 R3H domain SUZ PF12752.2 XP_011276689.1 - 0.00034 21.0 4.4 0.00034 21.0 3.0 2.8 2 0 0 2 2 2 1 SUZ domain Ufd2P_core PF10408.4 XP_011276690.1 - 1.8e-184 614.5 13.4 1.8e-184 614.5 9.3 1.6 2 0 0 2 2 2 1 Ubiquitin elongating factor core U-box PF04564.10 XP_011276690.1 - 2.6e-25 88.1 0.9 2.6e-25 88.1 0.6 2.5 3 0 0 3 3 3 1 U-box domain Ribosomal_L29 PF00831.18 XP_011276691.1 - 7e-19 67.2 2.9 7e-19 67.2 2.0 2.3 2 1 0 2 2 2 1 Ribosomal L29 protein DUF4404 PF14357.1 XP_011276691.1 - 0.036 14.4 0.6 0.082 13.3 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) MRP-L47 PF06984.8 XP_011276691.1 - 0.42 10.5 3.5 0.35 10.7 0.7 2.2 2 2 0 2 2 2 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Snapin_Pallidin PF14712.1 XP_011276691.1 - 7.4 6.9 9.9 0.44 10.8 2.6 1.9 2 0 0 2 2 2 0 Snapin/Pallidin Arf PF00025.16 XP_011276692.1 - 1.2e-80 268.8 0.1 1.3e-80 268.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 XP_011276692.1 - 6.7e-14 51.5 0.0 8.3e-14 51.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 XP_011276692.1 - 3.8e-13 49.1 0.0 4e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 XP_011276692.1 - 2.5e-12 46.2 1.3 1.8e-09 36.7 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 XP_011276692.1 - 2.5e-11 43.1 0.0 3e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 XP_011276692.1 - 2.7e-09 37.5 0.0 3.7e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 XP_011276692.1 - 3.9e-06 26.8 0.0 5.1e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 XP_011276692.1 - 0.0083 15.2 0.4 0.016 14.2 0.3 1.7 1 1 0 1 1 1 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 XP_011276692.1 - 0.0091 15.4 0.1 0.055 12.8 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 XP_011276692.1 - 0.081 12.7 0.1 0.14 12.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 XP_011276692.1 - 0.16 11.4 0.3 2.4 7.6 0.1 2.2 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Prenyltransf PF01255.14 XP_011276693.1 - 0.0011 18.1 0.0 0.0042 16.2 0.0 2.0 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Sugar_tr PF00083.19 XP_011276694.1 - 4.5e-117 391.3 28.1 5.4e-117 391.1 19.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 XP_011276694.1 - 9.4e-16 57.4 44.7 8.4e-15 54.3 8.3 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.4 XP_011276694.1 - 0.17 11.8 2.7 9.7 6.2 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) Ank_2 PF12796.2 XP_011276695.1 - 1e-76 253.3 0.0 1.1e-16 60.9 0.0 3.4 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.1 XP_011276695.1 - 8.7e-39 130.6 0.1 7.6e-09 35.5 0.0 5.1 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.25 XP_011276695.1 - 9.4e-38 126.1 0.0 2.2e-08 33.5 0.0 6.5 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.1 XP_011276695.1 - 5.1e-33 112.8 0.7 2.9e-07 30.8 0.0 5.9 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 XP_011276695.1 - 3.6e-31 104.0 0.0 2e-05 24.4 0.0 6.5 7 0 0 7 7 7 5 Ankyrin repeat Band_7 PF01145.20 XP_011276696.1 - 3.8e-23 82.3 1.6 5.5e-23 81.7 1.1 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family SMI1_KNR4 PF09346.5 XP_011276697.1 - 5.1e-36 123.5 0.0 6.8e-35 119.9 0.0 2.5 1 1 1 2 2 2 1 SMI1 / KNR4 family (SUKH-1) DIE2_ALG10 PF04922.7 XP_011276698.1 - 4.9e-105 351.6 32.6 4.9e-105 351.6 22.6 1.4 2 0 0 2 2 2 1 DIE2/ALG10 family Lectin_C PF00059.16 XP_011276699.1 - 0.00012 22.6 12.4 0.0014 19.2 1.6 3.4 4 1 1 5 5 5 2 Lectin C-type domain WD40 PF00400.27 XP_011276700.1 - 4.5e-12 45.3 7.9 0.0046 16.8 0.0 6.6 7 0 0 7 7 7 3 WD domain, G-beta repeat eIF2A PF08662.6 XP_011276700.1 - 0.02 14.6 0.1 0.073 12.7 0.0 2.0 1 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A MerR PF00376.18 XP_011276700.1 - 0.038 13.5 0.5 1.2 8.8 0.0 2.6 2 0 0 2 2 2 0 MerR family regulatory protein Ferric_reduct PF01794.14 XP_011276701.1 - 1.3e-08 35.0 2.6 3e-08 33.8 1.8 1.5 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 XP_011276701.1 - 6.1e-08 32.7 0.0 1.1e-06 28.6 0.0 2.6 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 XP_011276701.1 - 0.00038 20.2 0.0 0.00077 19.3 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ribosomal_S2 PF00318.15 XP_011276702.1 - 6.2e-39 133.3 0.3 1.5e-19 70.0 0.1 2.2 1 1 1 2 2 2 2 Ribosomal protein S2 MRP-S33 PF08293.6 XP_011276703.1 - 1.9e-24 85.4 0.2 2.4e-24 85.1 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 Gpi1 PF05024.10 XP_011276704.1 - 3.9e-55 186.4 15.4 3.9e-55 186.4 10.7 2.5 2 0 0 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) Herpes_IE1 PF07340.6 XP_011276704.1 - 0.0099 14.3 0.0 0.016 13.6 0.0 1.2 1 0 0 1 1 1 1 Cytomegalovirus IE1 protein Ion_trans PF00520.26 XP_011276705.1 - 2.2e-97 324.1 92.4 1.5e-34 119.0 8.8 5.1 4 1 0 4 4 4 4 Ion transport protein zf-ZPR1 PF03367.8 XP_011276706.1 - 8.9e-117 385.8 1.0 2.4e-57 192.6 0.0 2.3 2 0 0 2 2 2 2 ZPR1 zinc-finger domain Bromo_TP PF07524.8 XP_011276706.1 - 0.024 14.3 0.0 5.2 6.8 0.0 3.2 3 0 0 3 3 3 0 Bromodomain associated Cytochrom_NNT PF03264.9 XP_011276706.1 - 0.16 11.3 2.7 6.5 6.1 0.4 2.6 2 0 0 2 2 2 0 NapC/NirT cytochrome c family, N-terminal region DZR PF12773.2 XP_011276706.1 - 6.7 6.6 11.2 5.6 6.8 1.2 3.3 2 2 1 3 3 3 0 Double zinc ribbon WD40 PF00400.27 XP_011276707.1 - 1.7e-09 37.2 0.0 6.5e-05 22.6 0.0 3.7 3 0 0 3 3 3 2 WD domain, G-beta repeat Kelch_1 PF01344.20 XP_011276707.1 - 0.12 11.9 0.1 11 5.6 0.1 2.7 2 0 0 2 2 2 0 Kelch motif RRM_5 PF13893.1 XP_011276708.1 - 0.0037 17.0 0.1 0.12 12.2 0.0 3.1 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WASH_WAHD PF11945.3 XP_011276708.1 - 0.058 12.6 0.2 0.12 11.6 0.1 1.5 1 0 0 1 1 1 0 WAHD domain of WASH complex SET_assoc PF11767.3 XP_011276708.1 - 0.12 11.6 0.1 0.51 9.6 0.0 2.0 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated MHCassoc_trimer PF08831.5 XP_011276708.1 - 0.27 11.1 1.1 3.8 7.4 0.1 3.0 3 0 0 3 3 3 0 Class II MHC-associated invariant chain trimerisation domain PUF PF00806.14 XP_011276709.1 - 2e-57 187.5 22.1 5.2e-08 31.9 0.1 8.7 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Dpoe2NT PF12213.3 XP_011276709.1 - 0.24 11.3 5.3 3.2 7.7 0.0 3.9 5 0 0 5 5 5 0 DNA polymerases epsilon N terminal Rap_GAP PF02145.10 XP_011276710.1 - 6.6e-59 198.4 6.3 1.9e-58 196.9 4.4 1.8 1 0 0 1 1 1 1 Rap/ran-GAP DUF3384 PF11864.3 XP_011276710.1 - 1e-41 142.9 39.7 1e-41 142.9 27.5 2.8 2 1 0 2 2 2 1 Domain of unknown function (DUF3384) Tuberin PF03542.11 XP_011276710.1 - 2.8e-20 72.7 7.6 1.6e-18 66.9 4.5 2.9 2 1 0 2 2 2 2 Tuberin SWIM PF04434.12 XP_011276710.1 - 0.029 13.8 0.2 0.3 10.5 0.0 2.3 2 0 0 2 2 2 0 SWIM zinc finger MFS_1 PF07690.11 XP_011276711.1 - 1.4e-36 125.9 20.6 4.9e-36 124.1 14.5 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Claudin_2 PF13903.1 XP_011276711.1 - 0.48 10.1 11.6 1.4 8.5 0.6 3.2 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF1772 PF08592.6 XP_011276711.1 - 0.93 9.2 9.9 0.4 10.4 0.4 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF1772) AA_permease PF00324.16 XP_011276712.1 - 1.3e-138 462.3 41.5 1.4e-138 462.1 28.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 XP_011276712.1 - 1.1e-42 146.0 44.9 1.4e-42 145.7 31.2 1.0 1 0 0 1 1 1 1 Amino acid permease ABC_membrane PF00664.18 XP_011276713.1 - 3.3e-54 184.1 47.3 2.9e-29 102.3 17.6 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 XP_011276713.1 - 5.5e-48 162.7 2.4 4.5e-29 101.4 0.1 3.4 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.14 XP_011276713.1 - 1.3e-09 37.5 10.8 0.0025 17.0 2.4 4.4 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 XP_011276713.1 - 2.8e-09 36.3 0.2 0.0016 17.9 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 XP_011276713.1 - 5e-08 32.3 0.8 0.0021 17.2 0.2 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 XP_011276713.1 - 1.8e-07 31.9 0.3 0.0035 18.1 0.0 3.2 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 XP_011276713.1 - 2.2e-07 30.8 1.5 0.0062 16.4 0.1 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase T2SE PF00437.15 XP_011276713.1 - 2.8e-06 26.4 0.1 0.01 14.7 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_21 PF13304.1 XP_011276713.1 - 3.2e-06 27.3 27.2 7.3e-05 22.8 0.5 6.4 4 3 1 6 6 5 2 AAA domain AAA_23 PF13476.1 XP_011276713.1 - 3.7e-05 24.1 16.2 0.0069 16.7 0.0 3.8 2 1 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 XP_011276713.1 - 3.9e-05 23.2 0.0 0.0085 15.5 0.0 2.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_16 PF13191.1 XP_011276713.1 - 9.5e-05 22.4 0.2 0.02 14.8 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain Dynamin_N PF00350.18 XP_011276713.1 - 0.00011 22.1 5.7 0.041 13.6 0.0 3.3 3 0 0 3 3 2 2 Dynamin family Miro PF08477.8 XP_011276713.1 - 0.00015 22.2 0.3 1.1 9.7 0.0 3.0 2 0 0 2 2 2 2 Miro-like protein ArgK PF03308.11 XP_011276713.1 - 0.00055 18.7 0.2 0.9 8.2 0.0 2.3 2 0 0 2 2 2 2 ArgK protein AAA_22 PF13401.1 XP_011276713.1 - 0.0007 19.7 4.7 1.3 9.1 0.4 3.4 2 1 0 2 2 2 2 AAA domain AAA_10 PF12846.2 XP_011276713.1 - 0.0009 18.7 0.3 0.86 8.9 0.0 2.7 2 0 0 2 2 2 2 AAA-like domain Zeta_toxin PF06414.7 XP_011276713.1 - 0.00099 18.2 0.0 0.088 11.8 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin NB-ARC PF00931.17 XP_011276713.1 - 0.0025 16.7 0.3 1.3 7.7 0.0 2.8 2 0 0 2 2 2 2 NB-ARC domain PRK PF00485.13 XP_011276713.1 - 0.0035 16.9 0.4 1.8 8.0 0.1 2.7 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_30 PF13604.1 XP_011276713.1 - 0.0042 16.6 0.6 1.5 8.3 0.0 2.7 3 0 0 3 3 3 1 AAA domain cobW PF02492.14 XP_011276713.1 - 0.0052 16.2 3.1 0.18 11.2 0.2 3.0 3 0 0 3 3 2 1 CobW/HypB/UreG, nucleotide-binding domain Sigma54_activat PF00158.21 XP_011276713.1 - 0.0067 15.9 0.0 1.3 8.4 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain TrwB_AAD_bind PF10412.4 XP_011276713.1 - 0.015 13.9 0.3 2.2 6.8 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_18 PF13238.1 XP_011276713.1 - 0.037 14.3 11.6 0.79 10.0 0.6 4.2 3 1 0 3 3 3 0 AAA domain RNA_helicase PF00910.17 XP_011276713.1 - 0.04 14.0 1.7 6.9 6.9 0.0 3.6 4 0 0 4 4 3 0 RNA helicase Arch_ATPase PF01637.13 XP_011276713.1 - 0.051 13.2 3.8 0.8 9.3 0.0 3.6 3 1 0 3 3 3 0 Archaeal ATPase AAA_25 PF13481.1 XP_011276713.1 - 0.082 12.2 0.1 2.8 7.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 XP_011276713.1 - 0.1 12.5 1.9 1.5 8.8 0.1 2.5 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 XP_011276713.1 - 0.1 12.3 4.8 4.5 6.9 0.4 3.2 3 0 0 3 3 3 0 NTPase DUF87 PF01935.12 XP_011276713.1 - 0.17 11.7 0.0 0.17 11.7 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function DUF87 ATP_bind_1 PF03029.12 XP_011276713.1 - 0.34 10.4 3.9 19 4.7 0.0 3.5 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 XP_011276713.1 - 0.38 10.1 2.8 15 4.9 0.0 2.9 3 0 0 3 3 2 0 Elongation factor Tu GTP binding domain IncA PF04156.9 XP_011276713.1 - 9.9 5.6 8.7 24 4.4 3.8 2.8 2 0 0 2 2 2 0 IncA protein DUF4448 PF14610.1 XP_011276714.1 - 9.8e-34 116.4 0.1 1.5e-33 115.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) SKG6 PF08693.5 XP_011276714.1 - 8.8e-05 21.7 1.1 0.00019 20.6 0.8 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain RIC3 PF15361.1 XP_011276714.1 - 0.091 12.9 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 GPI-anchored PF10342.4 XP_011276714.1 - 0.9 10.0 6.1 0.15 12.5 1.1 2.1 2 0 0 2 2 2 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family ABC_membrane PF00664.18 XP_011276715.1 - 5.4e-62 209.7 27.4 1.2e-32 113.4 3.0 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 XP_011276715.1 - 5.6e-48 162.7 0.1 3.7e-30 105.0 0.1 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 XP_011276715.1 - 3.1e-10 39.6 1.8 0.0032 16.7 0.8 4.1 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 XP_011276715.1 - 1e-09 38.7 5.5 0.025 14.5 0.1 5.5 4 2 1 5 5 5 3 AAA domain AAA_29 PF13555.1 XP_011276715.1 - 7.1e-07 28.6 0.3 0.016 14.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 XP_011276715.1 - 1.6e-06 28.2 0.6 0.009 16.0 0.2 2.6 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.18 XP_011276715.1 - 9.5e-06 25.5 0.7 0.25 11.2 0.0 3.4 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_10 PF12846.2 XP_011276715.1 - 5e-05 22.8 0.3 0.34 10.2 0.0 3.0 2 1 1 3 3 3 2 AAA-like domain FtsK_SpoIIIE PF01580.13 XP_011276715.1 - 0.00014 21.3 0.0 0.29 10.6 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_25 PF13481.1 XP_011276715.1 - 0.00022 20.6 0.1 0.3 10.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 XP_011276715.1 - 0.00024 21.9 0.1 0.3 11.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 XP_011276715.1 - 0.00051 20.1 1.0 0.2 11.7 0.0 3.4 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 XP_011276715.1 - 0.0013 17.9 0.1 0.24 10.5 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_23 PF13476.1 XP_011276715.1 - 0.0023 18.2 7.5 0.99 9.6 2.1 3.5 3 1 0 3 3 3 2 AAA domain DUF87 PF01935.12 XP_011276715.1 - 0.0025 17.6 6.0 0.067 12.9 0.1 3.5 3 0 0 3 3 3 1 Domain of unknown function DUF87 AAA_18 PF13238.1 XP_011276715.1 - 0.0037 17.5 0.1 0.69 10.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 XP_011276715.1 - 0.0038 17.7 0.2 2.8 8.4 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein T2SE PF00437.15 XP_011276715.1 - 0.0093 14.8 0.0 0.41 9.5 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_33 PF13671.1 XP_011276715.1 - 0.012 15.5 0.9 2.1 8.1 0.1 3.2 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.18 XP_011276715.1 - 0.018 14.8 1.4 0.24 11.2 0.1 2.7 2 0 0 2 2 2 0 Dynamin family AAA_30 PF13604.1 XP_011276715.1 - 0.02 14.4 0.7 13 5.2 0.0 3.2 2 1 0 2 2 2 0 AAA domain NACHT PF05729.7 XP_011276715.1 - 0.031 13.9 0.2 0.75 9.4 0.0 2.8 2 0 0 2 2 2 0 NACHT domain MobB PF03205.9 XP_011276715.1 - 0.043 13.5 0.3 8.4 6.1 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 XP_011276715.1 - 0.044 12.5 0.1 7.7 5.2 0.0 2.3 2 0 0 2 2 2 0 ArgK protein GTP_EFTU PF00009.22 XP_011276715.1 - 0.062 12.7 0.0 5.6 6.3 0.0 2.6 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain RNA_helicase PF00910.17 XP_011276715.1 - 0.095 12.8 0.2 57 3.9 0.0 3.7 3 0 0 3 3 3 0 RNA helicase MFS_1 PF07690.11 XP_011276716.1 - 1.2e-29 103.1 16.5 1.2e-29 103.1 11.4 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily OPT PF03169.10 XP_011276717.1 - 2.2e-140 469.0 50.7 2.6e-140 468.8 35.2 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein APH PF01636.18 XP_011276717.1 - 2.3e-30 106.0 0.0 3.5e-30 105.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 XP_011276717.1 - 3.4e-07 29.6 0.0 6.3e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.15 XP_011276717.1 - 0.0003 20.4 0.0 0.00051 19.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Synaptobrevin PF00957.16 XP_011276717.1 - 0.24 10.9 0.5 1.4 8.6 0.3 2.3 1 0 0 1 1 1 0 Synaptobrevin zf-C2H2 PF00096.21 XP_011276718.1 - 4.7e-08 32.9 19.6 0.0019 18.3 1.2 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 XP_011276718.1 - 4.3e-06 26.7 13.9 0.0028 17.8 0.1 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 XP_011276718.1 - 4.4e-05 23.5 17.3 0.011 15.9 0.8 3.9 4 0 0 4 4 4 3 C2H2-type zinc finger HVSL PF09749.4 XP_011276719.1 - 1.1e-17 63.8 0.6 1.6e-17 63.3 0.4 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein Ribonuc_L-PSP PF01042.16 XP_011276719.1 - 0.12 12.1 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Endoribonuclease L-PSP 2-oxoacid_dh PF00198.18 XP_011276720.1 - 2.6e-79 265.7 0.1 3.6e-79 265.2 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 XP_011276720.1 - 1.5e-17 62.9 0.5 2.8e-17 62.1 0.1 1.6 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 XP_011276720.1 - 0.00012 21.6 0.1 0.17 11.5 0.0 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like GCV_H PF01597.14 XP_011276720.1 - 0.005 16.5 0.0 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 Glycine cleavage H-protein HlyD_3 PF13437.1 XP_011276720.1 - 0.011 16.0 0.1 0.58 10.5 0.0 2.4 1 1 1 2 2 2 0 HlyD family secretion protein GAGA_bind PF06217.7 XP_011276720.1 - 0.21 11.5 2.3 0.29 11.0 1.6 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Choline_kinase PF01633.15 XP_011276721.1 - 1.3e-59 201.3 0.6 1.3e-59 201.3 0.4 1.8 2 0 0 2 2 2 1 Choline/ethanolamine kinase Choline_kin_N PF04428.9 XP_011276721.1 - 8.2e-12 44.4 0.1 2.4e-11 42.9 0.0 1.8 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.18 XP_011276721.1 - 1.1e-07 31.8 0.0 0.0072 16.0 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family EcKinase PF02958.15 XP_011276721.1 - 0.052 12.6 0.1 0.43 9.6 0.0 2.1 2 0 0 2 2 2 0 Ecdysteroid kinase MFS_1 PF07690.11 XP_011276722.1 - 4.4e-38 130.9 23.3 6.8e-37 126.9 14.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 XP_011276722.1 - 1.4e-13 50.2 3.9 1.4e-13 50.2 2.7 2.8 3 0 0 3 3 3 2 Sugar (and other) transporter Mss4 PF04421.8 XP_011276723.1 - 2.4e-11 43.2 0.3 6.3e-07 29.1 0.0 2.2 2 0 0 2 2 2 2 Mss4 protein IBR PF01485.16 XP_011276723.1 - 0.072 12.9 1.9 0.17 11.7 1.3 1.8 1 1 0 1 1 1 0 IBR domain zf-H2C2_2 PF13465.1 XP_011276724.1 - 4.3e-08 33.0 18.9 5.8e-05 23.1 3.7 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 XP_011276724.1 - 2.3e-07 30.7 14.3 0.00094 19.3 2.5 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 XP_011276724.1 - 0.0023 18.1 18.5 0.027 14.7 2.7 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger MARVEL PF01284.18 XP_011276726.1 - 3.1e-06 27.0 0.1 0.01 15.6 0.0 2.6 2 1 0 2 2 2 2 Membrane-associating domain Na_Ca_ex PF01699.19 XP_011276727.1 - 7.9e-31 106.5 20.2 4.1e-16 58.8 3.7 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein CDC45 PF02724.9 XP_011276727.1 - 0.46 8.4 2.2 0.72 7.8 1.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Sugar_tr PF00083.19 XP_011276728.1 - 9.7e-77 258.4 29.6 1.2e-76 258.1 20.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 XP_011276728.1 - 9.1e-22 77.2 31.9 8.8e-21 74.0 17.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 XP_011276728.1 - 1.6e-11 43.2 27.6 4.5e-06 25.3 6.2 3.2 2 1 1 3 3 3 3 MFS/sugar transport protein Sugar_tr PF00083.19 XP_011276729.1 - 3.5e-81 273.0 28.1 4.5e-81 272.7 19.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 XP_011276729.1 - 1.9e-17 63.0 28.5 1.9e-17 63.0 19.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 XP_011276729.1 - 5.3e-07 28.3 34.9 0.0025 16.2 7.6 3.9 3 1 1 4 4 4 3 MFS/sugar transport protein Alpha-amylase PF00128.19 XP_011276730.1 - 8.6e-99 330.8 4.9 1.4e-98 330.1 3.4 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 XP_011276730.1 - 0.002 17.1 0.4 0.008 15.1 0.0 2.0 2 0 0 2 2 2 1 glucanotransferase domain of human glycogen debranching enzyme Fungal_trans PF04082.13 XP_011276731.1 - 2.1e-09 36.6 0.5 3.5e-09 35.9 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 XP_011276731.1 - 8.4e-06 25.6 7.0 8.4e-06 25.6 4.9 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Swi3 PF07962.7 XP_011276731.1 - 0.011 15.3 0.2 0.1 12.2 0.0 2.4 2 0 0 2 2 2 0 Replication Fork Protection Component Swi3 Cys_Met_Meta_PP PF01053.15 XP_011276732.1 - 3.3e-145 483.2 0.0 3.7e-145 483.0 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 XP_011276732.1 - 3.3e-12 46.0 0.0 5.5e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 XP_011276732.1 - 4.4e-11 42.4 0.0 1.9e-10 40.3 0.1 1.9 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 XP_011276732.1 - 5e-09 35.3 0.2 7.8e-09 34.7 0.2 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 XP_011276732.1 - 1.6e-06 27.4 0.0 2.9e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.6 XP_011276732.1 - 0.0034 15.7 0.0 0.0053 15.1 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.11 XP_011276732.1 - 0.011 14.4 0.0 0.017 13.8 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein SLA_LP_auto_ag PF05889.8 XP_011276732.1 - 0.13 10.6 0.0 0.2 10.0 0.0 1.2 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) zf-CCCH PF00642.19 XP_011276733.1 - 7e-21 73.4 18.8 2.1e-12 46.4 2.6 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 XP_011276733.1 - 0.09 12.8 13.9 0.22 11.6 1.7 2.4 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type HrpB7 PF09486.5 XP_011276733.1 - 1.6 8.6 10.6 2.5 8.0 7.3 1.3 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) MFS_1 PF07690.11 XP_011276735.1 - 1.8e-30 105.8 24.2 2.2e-30 105.5 16.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily SPC25 PF06703.6 XP_011276735.1 - 0.49 9.9 6.4 0.066 12.7 0.7 2.1 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Oxidored_FMN PF00724.15 XP_011276736.1 - 3.4e-94 315.6 0.0 3.8e-94 315.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Acetyltransf_1 PF00583.19 XP_011276737.1 - 1.3e-13 50.7 0.0 2e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 XP_011276737.1 - 5e-06 26.7 0.0 6.6e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 XP_011276737.1 - 0.0016 18.1 0.0 0.0025 17.5 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 XP_011276737.1 - 0.0027 17.6 0.0 0.0032 17.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 XP_011276737.1 - 0.0027 17.8 0.0 0.0035 17.4 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 XP_011276737.1 - 0.0043 17.1 0.0 0.0059 16.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 XP_011276737.1 - 0.017 14.7 0.0 0.051 13.1 0.0 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 XP_011276737.1 - 0.028 14.3 0.0 0.059 13.2 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Foamy_BEL PF03274.9 XP_011276737.1 - 0.14 11.4 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Foamy virus BEL 1/2 protein OB_NTP_bind PF07717.11 XP_011276738.1 - 9.6e-28 96.2 0.1 5.7e-27 93.8 0.1 2.4 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 XP_011276738.1 - 1.4e-22 79.5 0.7 4.8e-22 77.9 0.0 2.3 2 0 0 2 2 2 1 Helicase associated domain (HA2) S1 PF00575.18 XP_011276738.1 - 7.1e-14 51.6 1.7 2.5e-13 49.8 1.2 2.0 1 0 0 1 1 1 1 S1 RNA binding domain Helicase_C PF00271.26 XP_011276738.1 - 2.5e-13 49.6 0.0 9e-13 47.9 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 XP_011276738.1 - 2.5e-06 27.6 0.0 1.2e-05 25.4 0.0 2.1 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 XP_011276738.1 - 1.5e-05 24.0 0.0 0.00013 20.9 0.0 2.4 3 0 0 3 3 3 1 Type II/IV secretion system protein DEAD PF00270.24 XP_011276738.1 - 1.7e-05 24.3 0.0 4.4e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ABC_tran PF00005.22 XP_011276738.1 - 0.0069 16.6 2.9 0.24 11.6 0.1 3.4 2 1 0 2 2 2 1 ABC transporter AAA_14 PF13173.1 XP_011276738.1 - 0.01 15.7 0.1 0.14 12.0 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 XP_011276738.1 - 0.033 13.7 0.0 0.067 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 XP_011276738.1 - 0.039 12.8 0.0 0.068 12.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Sigma54_activ_2 PF14532.1 XP_011276738.1 - 0.11 12.4 0.0 0.39 10.7 0.0 1.9 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_23 PF13476.1 XP_011276738.1 - 0.14 12.4 0.1 0.14 12.4 0.0 3.7 3 2 1 4 4 3 0 AAA domain Proteasome PF00227.21 XP_011276739.1 - 8e-39 132.8 0.0 9.3e-39 132.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit DNA_primase_S PF01896.14 XP_011276740.1 - 9.3e-56 187.6 0.3 1.5e-55 186.9 0.2 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit Cellulase PF00150.13 XP_011276741.1 - 2.2e-12 46.7 2.6 6.1e-06 25.6 0.5 2.8 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) WD40 PF00400.27 XP_011276742.1 - 1.7e-20 72.0 0.5 5.2e-05 22.9 0.0 7.7 8 0 0 8 8 8 5 WD domain, G-beta repeat Apc4_WD40 PF12894.2 XP_011276742.1 - 1.9e-06 27.2 0.0 0.01 15.2 0.0 3.7 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain CPSF_A PF03178.10 XP_011276742.1 - 0.0043 16.1 0.0 0.26 10.3 0.0 2.3 1 1 0 2 2 2 2 CPSF A subunit region Trp_dioxygenase PF03301.8 XP_011276743.1 - 0.032 13.3 0.2 0.049 12.7 0.1 1.2 1 0 0 1 1 1 0 Tryptophan 2,3-dioxygenase Aconitase PF00330.15 XP_011276744.1 - 3.9e-181 602.5 0.1 1.2e-180 600.9 0.1 1.7 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 XP_011276744.1 - 4e-46 156.3 0.0 7.9e-46 155.4 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain PI3_PI4_kinase PF00454.22 XP_011276745.1 - 2.1e-40 138.6 0.0 6.4e-40 137.0 0.0 1.9 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 XP_011276745.1 - 1.3e-17 63.6 0.0 4.1e-17 61.9 0.0 1.8 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) eIF-6 PF01912.13 XP_011276746.1 - 8.1e-85 282.9 0.5 1.1e-84 282.4 0.3 1.2 1 0 0 1 1 1 1 eIF-6 family Phage_holin_6 PF10746.4 XP_011276746.1 - 0.13 12.0 0.2 0.34 10.6 0.0 1.7 2 0 0 2 2 2 0 Phage holin family 6 AAA_2 PF07724.9 XP_011276747.1 - 2.4e-47 161.0 1.5 3.6e-46 157.2 0.0 3.4 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 XP_011276747.1 - 5.8e-25 88.0 0.2 4.2e-14 52.8 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 XP_011276747.1 - 2.2e-22 78.7 0.8 2.2e-22 78.7 0.6 2.5 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 XP_011276747.1 - 1.9e-16 60.0 0.1 6.9e-10 38.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 XP_011276747.1 - 2e-12 46.9 0.3 3.5e-08 33.1 0.1 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain Clp_N PF02861.15 XP_011276747.1 - 1.4e-11 44.1 3.5 2.2e-08 33.9 0.2 3.4 2 0 0 2 2 2 2 Clp amino terminal domain AAA_16 PF13191.1 XP_011276747.1 - 6.1e-11 42.6 9.5 8.9e-05 22.5 0.0 5.3 3 3 1 5 5 5 2 AAA ATPase domain AAA_22 PF13401.1 XP_011276747.1 - 3.7e-10 40.0 0.3 0.00084 19.4 0.0 3.4 2 1 0 2 2 2 2 AAA domain AAA_14 PF13173.1 XP_011276747.1 - 1.4e-07 31.4 0.0 0.0089 15.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 XP_011276747.1 - 6.7e-05 22.0 0.1 0.0018 17.3 0.0 2.8 3 0 0 3 3 3 1 Zeta toxin AAA_17 PF13207.1 XP_011276747.1 - 8e-05 23.4 4.2 0.062 14.1 0.0 3.8 4 1 0 4 4 3 2 AAA domain AAA_3 PF07726.6 XP_011276747.1 - 0.00018 21.1 0.0 0.031 13.8 0.0 3.0 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 XP_011276747.1 - 0.00033 19.8 0.0 0.28 10.3 0.0 3.4 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI NACHT PF05729.7 XP_011276747.1 - 0.00047 19.8 0.0 0.29 10.7 0.0 2.9 2 0 0 2 2 2 1 NACHT domain AAA_19 PF13245.1 XP_011276747.1 - 0.00098 18.8 0.0 0.36 10.5 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA_18 PF13238.1 XP_011276747.1 - 0.0021 18.3 2.5 0.55 10.5 0.0 4.0 3 1 1 4 4 4 1 AAA domain AAA_33 PF13671.1 XP_011276747.1 - 0.0025 17.6 0.3 0.13 12.1 0.0 3.1 3 0 0 3 3 3 1 AAA domain Torsin PF06309.6 XP_011276747.1 - 0.0037 17.1 0.0 0.021 14.7 0.0 2.2 2 0 0 2 2 2 1 Torsin IstB_IS21 PF01695.12 XP_011276747.1 - 0.004 16.5 0.0 1.4 8.2 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein Arch_ATPase PF01637.13 XP_011276747.1 - 0.005 16.5 4.7 0.77 9.4 0.1 4.3 2 2 1 3 3 3 1 Archaeal ATPase SRP54 PF00448.17 XP_011276747.1 - 0.016 14.6 0.0 0.23 10.8 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ABC_tran PF00005.22 XP_011276747.1 - 0.021 15.0 1.3 1.1 9.5 0.0 3.4 3 0 0 3 3 3 0 ABC transporter MobB PF03205.9 XP_011276747.1 - 0.024 14.3 0.0 5.5 6.6 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 XP_011276747.1 - 0.027 13.9 0.9 2.5 7.4 0.0 3.4 4 0 0 4 4 4 0 AAA-like domain APS_kinase PF01583.15 XP_011276747.1 - 0.035 13.7 0.1 0.13 11.9 0.0 2.0 2 0 0 2 2 2 0 Adenylylsulphate kinase RNA_helicase PF00910.17 XP_011276747.1 - 0.039 14.1 0.2 9.7 6.4 0.0 3.0 3 0 0 3 3 2 0 RNA helicase PEPCK_ATP PF01293.15 XP_011276747.1 - 0.074 11.5 0.0 0.14 10.6 0.0 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase CRT10 PF08728.5 XP_011276748.1 - 1.8e-80 270.9 4.5 8.1e-51 172.8 0.3 2.1 1 1 1 2 2 2 2 CRT10 SNF2_N PF00176.18 XP_011276749.1 - 6.5e-82 274.6 0.6 6.5e-82 274.6 0.4 2.3 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.20 XP_011276749.1 - 2.1e-19 69.2 0.9 5.8e-19 67.8 0.6 1.8 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.26 XP_011276749.1 - 7.6e-18 64.1 0.1 1.5e-16 59.9 0.0 3.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SnAC PF14619.1 XP_011276749.1 - 4.8e-13 49.0 4.0 4.8e-13 49.0 2.8 4.3 4 2 0 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex HSA PF07529.8 XP_011276749.1 - 2.2e-05 24.1 9.0 2.2e-05 24.1 6.3 3.1 2 0 0 2 2 2 1 HSA R3H PF01424.17 XP_011276750.1 - 2.5e-14 52.6 0.1 6.2e-14 51.4 0.0 1.7 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.12 XP_011276750.1 - 0.0027 17.6 33.7 0.0035 17.2 9.5 11.8 17 1 0 17 17 17 4 NF-X1 type zinc finger Methyltransf_16 PF10294.4 XP_011276751.1 - 6.9e-15 54.9 0.1 8.3e-15 54.6 0.1 1.1 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 XP_011276751.1 - 0.027 13.8 0.1 0.033 13.5 0.1 1.2 1 0 0 1 1 1 0 Methyltransferase small domain MRP-S25 PF13741.1 XP_011276752.1 - 3.2e-81 272.1 2.8 3.7e-81 271.9 2.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.4 XP_011276752.1 - 0.0012 18.6 1.5 0.022 14.6 0.1 2.4 1 1 0 2 2 2 1 Mitochondrial ribosomal protein S23 PPR_3 PF13812.1 XP_011276753.1 - 0.00096 19.2 0.0 2.7 8.4 0.0 4.2 5 0 0 5 5 5 1 Pentatricopeptide repeat domain PPR_2 PF13041.1 XP_011276753.1 - 0.008 16.1 1.5 3.1 7.8 0.0 3.6 3 0 0 3 3 3 2 PPR repeat family DUF3900 PF13039.1 XP_011276753.1 - 0.0093 15.5 2.6 0.01 15.4 0.4 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3900) PPR PF01535.15 XP_011276753.1 - 0.16 11.9 2.5 21 5.3 0.2 3.4 3 0 0 3 3 3 0 PPR repeat Homeobox_KN PF05920.6 XP_011276754.1 - 4.4e-17 61.4 1.1 3.6e-16 58.5 1.3 2.2 2 0 0 2 2 2 1 Homeobox KN domain Homeobox PF00046.24 XP_011276754.1 - 0.00069 19.1 1.8 0.002 17.6 1.3 1.8 1 0 0 1 1 1 1 Homeobox domain PAT1 PF09770.4 XP_011276754.1 - 0.34 9.0 35.6 0.36 8.9 24.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 XP_011276754.1 - 0.74 9.6 19.1 0.86 9.4 13.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sugar_tr PF00083.19 XP_011276755.1 - 5.9e-112 374.5 29.0 7e-112 374.2 20.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 XP_011276755.1 - 2.7e-25 88.8 30.6 5.6e-25 87.7 13.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_19 PF14559.1 XP_011276755.1 - 0.037 14.3 0.1 0.059 13.7 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat Sugar_tr PF00083.19 XP_011276756.1 - 7.9e-111 370.8 31.3 8.9e-111 370.6 21.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 XP_011276756.1 - 1e-25 90.2 41.5 3.8e-22 78.4 12.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 XP_011276756.1 - 0.0051 14.9 1.2 0.0096 14.0 0.8 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector DUF367 PF04034.8 XP_011276756.1 - 0.084 12.4 0.1 12 5.5 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF367) Rhomboid PF01694.17 XP_011276757.1 - 3e-36 124.6 10.9 3e-36 124.6 7.5 2.5 3 0 0 3 3 3 1 Rhomboid family Apis_Csd PF11671.3 XP_011276757.1 - 0.023 14.5 9.0 0.046 13.5 6.2 1.5 1 0 0 1 1 1 0 Complementary sex determiner protein P12 PF12669.2 XP_011276757.1 - 9.4 6.5 9.7 0.16 12.1 1.1 2.2 2 0 0 2 2 2 0 Virus attachment protein p12 family DUF4191 PF13829.1 XP_011276757.1 - 9.9 5.2 6.8 3.7 6.6 0.4 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4191) WD40 PF00400.27 XP_011276758.1 - 1.3e-06 28.0 0.1 0.0039 17.0 0.0 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat Gmad1 PF10647.4 XP_011276758.1 - 0.12 11.7 0.1 0.25 10.6 0.0 1.5 2 0 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain Arrestin_C PF02752.17 XP_011276759.1 - 1.2e-19 70.8 0.6 3.7e-19 69.1 0.1 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 XP_011276759.1 - 4.4e-12 46.0 0.1 8.9e-09 35.3 0.0 2.5 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 XP_011276759.1 - 0.0094 15.4 0.1 0.059 12.8 0.0 2.3 3 0 0 3 3 3 1 Arrestin_N terminal like SNARE PF05739.14 XP_011276760.1 - 2.1e-17 62.5 6.3 2.1e-17 62.5 4.3 2.5 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 XP_011276760.1 - 1.6e-08 34.6 3.0 1.6e-08 34.6 2.0 3.6 2 1 1 3 3 3 1 Syntaxin DUF3357 PF11837.3 XP_011276760.1 - 0.003 17.3 0.0 0.0065 16.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3357) Synaptobrevin PF00957.16 XP_011276760.1 - 0.014 14.9 4.5 0.014 14.9 3.1 3.0 4 0 0 4 4 4 0 Synaptobrevin ATP-synt_8 PF00895.15 XP_011276760.1 - 0.09 12.9 1.4 0.35 11.0 1.0 2.0 1 0 0 1 1 1 0 ATP synthase protein 8 FAM176 PF14851.1 XP_011276760.1 - 0.15 11.7 0.1 0.15 11.7 0.0 2.4 3 1 0 3 3 3 0 FAM176 family INO80_Ies4 PF08193.6 XP_011276760.1 - 1.5 8.6 6.3 0.09 12.6 0.4 1.7 2 0 0 2 2 2 0 INO80 complex subunit Ies4 SUR7 PF06687.7 XP_011276761.1 - 3.5e-18 65.9 21.1 5.7e-18 65.2 14.6 1.4 1 0 0 1 1 1 1 SUR7/PalI family DUF788 PF05620.6 XP_011276761.1 - 0.046 13.5 1.0 0.11 12.3 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF788) PIP5K PF01504.13 XP_011276762.1 - 1.3e-64 217.7 0.8 3.2e-64 216.4 0.5 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 XP_011276762.1 - 2.3e-25 89.1 0.1 4.3e-25 88.2 0.0 1.3 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 XP_011276762.1 - 4.9e-16 58.3 9.4 4.9e-16 58.3 6.5 1.8 2 0 0 2 2 2 1 FYVE zinc finger Peptidase_M28 PF04389.12 XP_011276763.1 - 2.8e-37 128.1 0.0 3.8e-37 127.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 ABC2_membrane PF01061.19 XP_011276764.1 - 5.8e-37 126.9 17.2 5.8e-37 126.9 11.9 2.0 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 XP_011276764.1 - 7.1e-29 100.8 0.1 1.6e-28 99.7 0.1 1.6 1 0 0 1 1 1 1 ABC transporter AAA_25 PF13481.1 XP_011276764.1 - 0.00052 19.4 0.1 0.054 12.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 XP_011276764.1 - 0.0018 17.5 0.3 0.0041 16.3 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SMC_N PF02463.14 XP_011276764.1 - 0.0034 16.6 0.1 0.027 13.7 0.1 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_18 PF13238.1 XP_011276764.1 - 0.0054 17.0 1.3 0.0075 16.5 0.1 1.8 2 0 0 2 2 1 1 AAA domain AAA_29 PF13555.1 XP_011276764.1 - 0.0093 15.4 0.2 0.02 14.3 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 XP_011276764.1 - 0.014 15.3 0.0 0.039 13.8 0.0 1.8 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.1 XP_011276764.1 - 0.015 15.2 0.2 0.029 14.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 XP_011276764.1 - 0.016 15.3 0.1 0.033 14.3 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 XP_011276764.1 - 0.045 14.5 0.2 0.14 12.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 XP_011276764.1 - 0.1 12.2 0.2 0.19 11.3 0.1 1.4 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 XP_011276764.1 - 0.11 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain DUF2399 PF09664.5 XP_011276764.1 - 0.18 11.6 0.0 1.1 9.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function C-terminus (DUF2399) AAA_33 PF13671.1 XP_011276764.1 - 0.21 11.4 0.0 0.37 10.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain HECT PF00632.20 XP_011276765.1 - 2.1e-83 280.0 8.9 2.7e-83 279.7 1.7 3.0 3 0 0 3 3 3 2 HECT-domain (ubiquitin-transferase) Flocculin_t3 PF13928.1 XP_011276766.1 - 1e-08 35.1 23.7 1e-08 35.1 16.5 4.0 4 0 0 4 4 4 1 Flocculin type 3 repeat MFS_1 PF07690.11 XP_011276767.1 - 1.1e-17 63.8 23.1 2.9e-17 62.4 16.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.11 XP_011276768.1 - 7.8e-18 64.3 21.2 1.1e-17 63.8 14.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF592 PF04574.8 XP_011276768.1 - 0.065 12.7 0.1 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF592) DUF4131 PF13567.1 XP_011276768.1 - 3.6 6.9 6.9 0.52 9.6 0.4 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) DAO PF01266.19 XP_011276769.1 - 1.4e-46 159.1 0.0 1.6e-46 158.9 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 XP_011276769.1 - 6.3e-06 26.2 0.1 0.00067 19.5 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 XP_011276769.1 - 5.1e-05 22.3 0.0 0.002 17.0 0.0 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 XP_011276769.1 - 0.00081 19.3 0.0 0.0027 17.7 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 XP_011276769.1 - 0.012 14.1 0.0 2.3 6.5 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.22 XP_011276769.1 - 0.024 15.0 0.0 0.059 13.7 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 XP_011276769.1 - 0.033 14.4 0.0 0.059 13.6 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox_3 PF13738.1 XP_011276769.1 - 0.036 14.1 0.0 0.14 12.1 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 XP_011276769.1 - 0.082 12.6 0.0 0.27 10.9 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding MFS_1 PF07690.11 XP_011276770.1 - 2.5e-19 69.2 24.4 3.5e-18 65.4 10.9 3.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Arteri_Gl PF00951.13 XP_011276770.1 - 0.031 13.8 0.1 0.09 12.3 0.1 1.8 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein SieB PF14163.1 XP_011276770.1 - 0.065 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Superinfection exclusion protein B DUF1516 PF07457.6 XP_011276770.1 - 0.1 12.6 1.6 8.9 6.4 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1516) Peptidase_C12 PF01088.16 XP_011276771.1 - 7.3e-55 185.4 0.0 8.5e-55 185.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 SAC3_GANP PF03399.11 XP_011276772.1 - 1.9e-51 174.5 3.9 3.2e-51 173.8 2.7 1.4 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 XP_011276772.1 - 5.2e-07 29.5 0.3 1.3e-06 28.2 0.2 1.7 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 Pkinase PF00069.20 XP_011276773.1 - 7.6e-72 241.5 0.0 9.5e-72 241.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011276773.1 - 1.5e-35 122.4 0.0 2e-35 122.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 XP_011276773.1 - 5e-08 32.2 0.0 1.2e-07 31.0 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Pkinase_C PF00433.19 XP_011276773.1 - 7.7e-08 32.7 0.7 2.1e-07 31.3 0.1 1.9 2 0 0 2 2 2 1 Protein kinase C terminal domain APH PF01636.18 XP_011276773.1 - 0.11 12.2 0.0 0.26 10.9 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family NAD_binding_6 PF08030.7 XP_011276774.1 - 2e-26 92.7 0.0 4e-26 91.7 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 XP_011276774.1 - 2.5e-20 72.3 0.0 4.7e-20 71.4 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 XP_011276774.1 - 2.8e-20 72.6 14.0 2.8e-20 72.6 9.7 2.3 2 1 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 XP_011276774.1 - 0.0019 18.7 0.0 3.5 8.2 0.0 2.8 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain FAD_binding_8 PF08022.7 XP_011276775.1 - 2.5e-22 78.7 0.1 5.3e-22 77.6 0.1 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 XP_011276775.1 - 1.4e-16 60.6 18.8 1.4e-16 60.6 13.1 2.4 2 1 1 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 XP_011276775.1 - 1.3e-12 47.9 0.0 2.3e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Tmemb_55A PF09788.4 XP_011276775.1 - 1.2 8.1 3.5 2.5 7.1 2.5 1.5 1 0 0 1 1 1 0 Transmembrane protein 55A DUF1467 PF07330.7 XP_011276776.1 - 0.042 13.6 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1467) DUF3112 PF11309.3 XP_011276776.1 - 4.2 7.1 8.1 3.9 7.2 0.1 3.0 2 1 0 3 3 3 0 Protein of unknown function (DUF3112) NAD_binding_6 PF08030.7 XP_011276777.1 - 1.5e-25 89.9 0.0 2.1e-25 89.4 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 XP_011276777.1 - 1.8e-23 82.3 0.0 3.3e-23 81.5 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 XP_011276777.1 - 3e-07 30.5 5.6 6e-07 29.5 3.9 1.5 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 XP_011276777.1 - 8.7e-05 23.0 0.0 0.57 10.7 0.0 2.7 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain MLANA PF14991.1 XP_011276777.1 - 0.079 12.9 0.4 0.2 11.6 0.3 1.8 1 0 0 1 1 1 0 Protein melan-A NAD_binding_6 PF08030.7 XP_011276778.1 - 1.3e-24 86.8 0.0 2.2e-24 86.1 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 XP_011276778.1 - 3.1e-23 81.6 0.0 5.9e-23 80.7 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 XP_011276778.1 - 2.7e-19 69.4 17.1 2.7e-19 69.4 11.8 1.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 XP_011276778.1 - 7.9e-05 23.1 0.0 0.32 11.5 0.0 2.5 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 XP_011276779.1 - 1.1e-27 96.8 0.0 2e-27 96.0 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 XP_011276779.1 - 5.2e-23 80.9 0.1 9.4e-23 80.0 0.1 1.4 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 XP_011276779.1 - 1.4e-21 76.8 12.4 1.4e-21 76.8 8.6 2.5 2 1 1 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 XP_011276779.1 - 0.00082 19.9 0.0 1.2 9.7 0.0 2.8 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain Fungal_trans_2 PF11951.3 XP_011276780.1 - 4.2e-26 91.4 2.2 5.3e-26 91.1 1.5 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 XP_011276781.1 - 1.1e-25 90.1 19.3 1.1e-25 90.1 13.4 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sel1 PF08238.7 XP_011276781.1 - 0.14 12.8 0.1 0.46 11.1 0.0 1.9 1 0 0 1 1 1 0 Sel1 repeat SRA1 PF07304.6 XP_011276782.1 - 0.035 13.8 0.1 0.075 12.7 0.1 1.5 1 0 0 1 1 1 0 Steroid receptor RNA activator (SRA1) IF-2B PF01008.12 XP_011276782.1 - 0.062 12.2 0.5 0.085 11.8 0.4 1.3 1 0 0 1 1 1 0 Initiation factor 2 subunit family NMT PF01233.14 XP_011276783.1 - 5.7e-78 260.1 0.0 9.1e-78 259.4 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.10 XP_011276783.1 - 4.2e-69 231.7 2.4 4.2e-69 231.7 1.7 1.7 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.1 XP_011276783.1 - 3e-06 27.0 0.0 5.1e-05 23.1 0.0 2.4 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 XP_011276783.1 - 0.0064 16.5 0.0 0.023 14.6 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 XP_011276783.1 - 0.026 14.6 0.1 0.081 13.0 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain WD40 PF00400.27 XP_011276784.1 - 2.8e-15 55.5 0.5 1.2e-05 24.9 0.3 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat Nop PF01798.13 XP_011276785.1 - 2.8e-59 198.7 0.0 5.5e-59 197.7 0.0 1.5 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 XP_011276785.1 - 4.1e-27 93.7 1.2 8.4e-27 92.7 0.1 2.2 2 0 0 2 2 2 1 NOSIC (NUC001) domain NOP5NT PF08156.8 XP_011276785.1 - 2.1e-22 79.0 1.5 2.1e-22 79.0 1.0 2.6 2 0 0 2 2 2 1 NOP5NT (NUC127) domain DDHD PF02862.12 XP_011276785.1 - 0.21 11.3 4.2 0.35 10.6 2.9 1.4 1 0 0 1 1 1 0 DDHD domain GAGA_bind PF06217.7 XP_011276785.1 - 0.33 10.8 9.5 0.5 10.2 6.6 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family RNA_polI_A34 PF08208.6 XP_011276785.1 - 0.56 9.8 26.8 0.92 9.1 18.6 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 CDC45 PF02724.9 XP_011276785.1 - 1.4 6.8 15.4 2 6.3 10.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Med19 PF10278.4 XP_011276785.1 - 1.9 8.0 22.9 4.4 6.9 15.9 1.6 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 HSP90 PF00183.13 XP_011276785.1 - 2.8 6.2 21.6 4.3 5.6 15.0 1.2 1 0 0 1 1 1 0 Hsp90 protein YqfQ PF14181.1 XP_011276785.1 - 5.4 7.0 14.4 14 5.6 10.0 1.6 1 0 0 1 1 1 0 YqfQ-like protein NOA36 PF06524.7 XP_011276786.1 - 0.65 9.1 7.9 0.86 8.8 5.5 1.2 1 0 0 1 1 1 0 NOA36 protein BBP1_N PF15271.1 XP_011276786.1 - 3.3 8.0 17.7 0.15 12.4 5.5 2.2 1 1 1 2 2 2 0 Spindle pole body component BBP1, Mps2-binding protein DUF4637 PF15470.1 XP_011276786.1 - 5.1 6.6 7.9 9.4 5.8 2.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) POC1 PF10450.4 XP_011276787.1 - 2.2e-09 36.4 3.1 3.2e-09 35.9 2.2 1.2 1 0 0 1 1 1 1 POC1 chaperone PD-C2-AF1 PF09310.5 XP_011276787.1 - 0.14 11.2 0.1 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 POU domain, class 2, associating factor 1 Prefoldin_2 PF01920.15 XP_011276788.1 - 7e-21 73.9 9.5 8.3e-21 73.7 6.6 1.2 1 0 0 1 1 1 1 Prefoldin subunit Cytokin-bind PF09265.5 XP_011276788.1 - 0.0052 15.9 0.7 0.0058 15.8 0.5 1.0 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding DUF2100 PF09873.4 XP_011276788.1 - 0.019 14.4 1.2 0.021 14.3 0.9 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2100) OMS28_porin PF03532.8 XP_011276788.1 - 0.051 12.6 2.7 1.9 7.4 0.2 2.0 1 1 1 2 2 2 0 OMS28 porin Prefoldin PF02996.12 XP_011276788.1 - 0.078 12.6 7.2 0.2 11.2 0.8 2.2 2 0 0 2 2 2 0 Prefoldin subunit TACC PF05010.9 XP_011276788.1 - 0.098 12.4 6.6 0.11 12.2 4.5 1.0 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) IncA PF04156.9 XP_011276788.1 - 0.11 12.1 7.4 0.26 10.8 5.1 1.6 1 1 0 1 1 1 0 IncA protein YgaB PF14182.1 XP_011276788.1 - 0.11 12.7 0.2 0.11 12.7 0.2 2.2 2 1 0 2 2 2 0 YgaB-like protein DUF1409 PF07197.7 XP_011276788.1 - 0.12 12.4 1.1 1.9 8.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1409) DUF1948 PF09185.5 XP_011276788.1 - 0.19 11.3 3.1 0.86 9.2 0.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1948) CENP-F_leu_zip PF10473.4 XP_011276788.1 - 0.23 11.3 10.1 0.58 10.0 0.9 2.0 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NPV_P10 PF05531.7 XP_011276788.1 - 0.35 11.1 4.3 1.4 9.2 0.4 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF342 PF03961.8 XP_011276788.1 - 0.37 9.1 6.0 0.43 8.9 4.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF1374 PF07118.6 XP_011276788.1 - 0.46 10.6 6.0 0.29 11.2 3.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1374) FliJ PF02050.11 XP_011276788.1 - 0.57 10.2 9.1 0.32 11.0 1.2 2.3 2 1 0 2 2 2 0 Flagellar FliJ protein ADIP PF11559.3 XP_011276788.1 - 0.58 10.0 8.8 1.2 9.0 1.0 2.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding FlaC_arch PF05377.6 XP_011276788.1 - 0.82 9.6 9.0 0.3 11.0 1.2 2.8 2 2 0 2 2 2 0 Flagella accessory protein C (FlaC) COQ9 PF08511.6 XP_011276789.1 - 3.1e-22 77.8 0.0 6.9e-22 76.7 0.0 1.6 1 0 0 1 1 1 1 COQ9 SieB PF14163.1 XP_011276789.1 - 0.064 12.8 0.3 0.13 11.8 0.2 1.5 1 0 0 1 1 1 0 Superinfection exclusion protein B ADH_N PF08240.7 XP_011276790.1 - 5.8e-27 93.5 3.7 5.8e-27 93.5 2.6 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 XP_011276790.1 - 5.1e-19 68.1 0.1 9.2e-19 67.2 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 XP_011276790.1 - 0.004 16.5 0.1 0.0073 15.7 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Gp_dh_N PF00044.19 XP_011276790.1 - 0.036 14.0 0.9 1.5 8.7 0.1 2.8 3 1 1 4 4 4 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain MobB PF03205.9 XP_011276790.1 - 0.077 12.7 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B zf-RanBP PF00641.13 XP_011276791.1 - 2e-18 65.1 13.8 8.7e-11 40.7 1.5 2.5 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.17 XP_011276791.1 - 7.4e-10 38.3 0.0 1.6e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.19 XP_011276791.1 - 9.5e-07 29.2 0.0 9.5e-07 29.2 0.0 2.2 2 0 0 2 2 2 1 Exonuclease RRM_6 PF14259.1 XP_011276791.1 - 1.3e-05 25.0 0.0 2.7e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Rubredoxin PF00301.15 XP_011276791.1 - 3.6 7.5 7.7 1.2 9.0 0.3 2.7 2 0 0 2 2 2 0 Rubredoxin DUF221 PF02714.10 XP_011276792.1 - 2.3e-100 335.6 21.2 2.3e-100 335.6 14.7 1.9 3 0 0 3 3 3 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 XP_011276792.1 - 3.1e-38 130.7 7.1 9.9e-38 129.1 5.0 1.9 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 XP_011276792.1 - 5.1e-16 58.9 0.2 1.5e-15 57.4 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4463) RRM_6 PF14259.1 XP_011276792.1 - 0.024 14.6 0.1 0.082 12.8 0.1 1.9 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Zn_clus PF00172.13 XP_011276793.1 - 8.9e-08 31.9 7.7 1.7e-07 31.0 5.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ham1p_like PF01725.11 XP_011276794.1 - 5.1e-50 169.4 0.0 5.8e-50 169.2 0.0 1.0 1 0 0 1 1 1 1 Ham1 family AAA_18 PF13238.1 XP_011276795.1 - 2.4e-27 95.7 0.4 2.4e-27 95.7 0.3 1.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 XP_011276795.1 - 3e-13 50.6 0.6 4.3e-13 50.1 0.4 1.5 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 XP_011276795.1 - 9.8e-05 21.5 0.0 0.00019 20.6 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA PF00004.24 XP_011276795.1 - 9.8e-05 22.5 0.0 0.00046 20.3 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 XP_011276795.1 - 0.00091 19.1 0.2 0.0027 17.6 0.0 1.7 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.1 XP_011276795.1 - 0.0023 17.9 0.0 0.0055 16.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 XP_011276795.1 - 0.0024 16.9 0.1 0.0051 15.8 0.0 1.5 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 XP_011276795.1 - 0.0037 17.1 0.0 0.79 9.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain KTI12 PF08433.5 XP_011276795.1 - 0.0058 15.8 0.0 0.027 13.6 0.0 1.8 2 0 0 2 2 2 1 Chromatin associated protein KTI12 DUF349 PF03993.7 XP_011276795.1 - 0.017 15.2 0.1 10 6.3 0.0 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) ADK PF00406.17 XP_011276795.1 - 0.018 14.9 0.1 0.36 10.7 0.1 2.1 1 1 0 1 1 1 0 Adenylate kinase RNA_helicase PF00910.17 XP_011276795.1 - 0.02 15.0 0.0 0.046 13.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF3221 PF11518.3 XP_011276795.1 - 0.025 14.2 0.4 0.046 13.3 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3221) dNK PF01712.14 XP_011276795.1 - 0.031 14.2 1.1 0.041 13.7 0.8 1.2 1 0 0 1 1 1 0 Deoxynucleoside kinase AAA_22 PF13401.1 XP_011276795.1 - 0.035 14.2 0.0 0.24 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 XP_011276795.1 - 0.054 13.8 0.1 0.11 12.7 0.1 1.8 1 1 0 1 1 1 0 ABC transporter Thymidylate_kin PF02223.12 XP_011276795.1 - 0.055 12.8 0.1 3.6 6.9 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase NTPase_1 PF03266.10 XP_011276795.1 - 0.056 13.1 0.3 0.15 11.7 0.0 1.8 2 0 0 2 2 2 0 NTPase Parvo_NS1 PF01057.12 XP_011276795.1 - 0.073 11.9 0.0 0.28 10.0 0.0 1.8 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Viral_helicase1 PF01443.13 XP_011276795.1 - 0.11 11.9 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.1 XP_011276795.1 - 0.12 12.3 0.0 0.27 11.1 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_19 PF13245.1 XP_011276795.1 - 0.15 11.8 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain NOT2_3_5 PF04153.13 XP_011276796.1 - 4.7e-33 113.9 3.9 4.7e-33 113.9 2.7 2.0 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family zf-Mss51 PF13824.1 XP_011276797.1 - 8.6e-21 73.5 1.3 1.7e-20 72.6 0.9 1.5 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 DUF1713 PF08213.6 XP_011276798.1 - 4.6e-11 42.1 23.0 7.5e-11 41.4 15.9 1.4 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) Heme_oxygenase PF01126.15 XP_011276799.1 - 4e-21 75.5 1.1 7.4e-21 74.6 0.8 1.4 1 1 0 1 1 1 1 Heme oxygenase DUF4065 PF13274.1 XP_011276799.1 - 0.055 14.1 1.1 3.6 8.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4065) Zn_peptidase_2 PF04298.7 XP_011276800.1 - 0.13 11.5 0.1 0.36 10.1 0.0 1.6 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase PRP1_N PF06424.7 XP_011276801.1 - 5.7e-39 133.4 2.1 5.7e-39 133.4 1.4 2.9 3 0 0 3 3 3 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 XP_011276801.1 - 6.4e-22 76.0 0.0 1.3 9.8 0.0 10.3 8 2 3 11 11 11 5 Tetratricopeptide repeat TPR_19 PF14559.1 XP_011276801.1 - 2.2e-14 53.5 5.2 0.0082 16.4 0.0 8.0 5 1 3 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.1 XP_011276801.1 - 4.9e-14 52.5 0.0 0.11 13.2 0.0 6.6 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 XP_011276801.1 - 4e-12 45.0 6.4 0.13 12.2 0.0 8.7 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_11 PF13414.1 XP_011276801.1 - 9.8e-11 41.1 15.4 0.04 13.5 0.0 8.3 6 4 4 10 10 10 6 TPR repeat TPR_12 PF13424.1 XP_011276801.1 - 2.4e-08 33.7 2.4 0.18 11.7 0.0 6.4 5 1 1 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.1 XP_011276801.1 - 2e-07 30.2 12.9 2.4 8.1 0.0 8.0 8 0 0 8 8 8 3 Tetratricopeptide repeat NARP1 PF12569.3 XP_011276801.1 - 2.7e-07 29.7 0.2 2e-05 23.5 0.0 3.0 2 1 0 3 3 3 1 NMDA receptor-regulated protein 1 TPR_15 PF13429.1 XP_011276801.1 - 3.8e-07 29.4 4.3 0.004 16.2 0.2 4.6 3 1 1 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 XP_011276801.1 - 0.00093 19.2 3.6 1.7 8.8 0.2 4.1 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 XP_011276801.1 - 0.014 14.9 4.7 3.4 7.4 0.0 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.1 XP_011276801.1 - 0.076 13.2 12.8 27 5.2 0.0 8.3 10 0 0 10 10 9 0 Tetratricopeptide repeat DUF2680 PF10925.3 XP_011276801.1 - 0.16 11.8 4.9 9.3 6.2 0.2 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2680) SHMT PF00464.14 XP_011276801.1 - 0.17 10.2 0.0 0.31 9.3 0.0 1.4 1 0 0 1 1 1 0 Serine hydroxymethyltransferase RPN7 PF10602.4 XP_011276801.1 - 5.6 6.3 10.8 0.18 11.1 0.1 3.3 4 0 0 4 4 4 0 26S proteasome subunit RPN7 ABC_tran PF00005.22 XP_011276803.1 - 3.2e-49 166.7 0.0 1.3e-26 93.4 0.0 3.7 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 XP_011276803.1 - 1.9e-15 57.6 4.9 2.7e-06 27.5 0.0 5.0 5 0 0 5 5 5 3 AAA domain SMC_N PF02463.14 XP_011276803.1 - 2.4e-11 43.2 0.0 0.013 14.7 0.0 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 XP_011276803.1 - 8.6e-09 36.0 0.7 0.0017 18.6 0.0 3.3 3 0 0 3 3 3 2 AAA domain Chromo PF00385.19 XP_011276803.1 - 3.1e-08 33.1 1.5 7.1e-08 32.0 1.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_29 PF13555.1 XP_011276803.1 - 3.4e-08 32.9 0.2 0.0096 15.4 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 XP_011276803.1 - 2e-06 28.6 0.0 0.11 13.2 0.0 3.1 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 XP_011276803.1 - 2.4e-06 27.4 0.0 0.022 14.6 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 XP_011276803.1 - 3.1e-06 26.4 0.0 0.017 14.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 XP_011276803.1 - 1.3e-05 25.3 0.0 0.049 13.7 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 XP_011276803.1 - 3.9e-05 23.2 0.6 0.28 10.5 0.0 3.3 4 0 0 4 4 4 2 AAA-like domain Miro PF08477.8 XP_011276803.1 - 6.2e-05 23.4 0.0 0.28 11.6 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein DUF87 PF01935.12 XP_011276803.1 - 9.3e-05 22.3 1.7 0.027 14.2 0.0 3.5 3 0 0 3 3 3 1 Domain of unknown function DUF87 ArgK PF03308.11 XP_011276803.1 - 0.00022 20.0 0.2 0.29 9.8 0.0 2.4 2 0 0 2 2 2 2 ArgK protein AAA_28 PF13521.1 XP_011276803.1 - 0.00045 20.2 0.0 0.16 11.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 XP_011276803.1 - 0.00065 20.0 1.4 0.34 11.2 0.0 3.5 3 1 0 3 3 3 1 AAA domain RNA_helicase PF00910.17 XP_011276803.1 - 0.00077 19.6 0.1 1.8 8.7 0.0 2.7 2 0 0 2 2 2 1 RNA helicase NACHT PF05729.7 XP_011276803.1 - 0.00084 19.0 0.1 0.91 9.1 0.0 2.7 2 0 0 2 2 2 1 NACHT domain MobB PF03205.9 XP_011276803.1 - 0.0011 18.7 0.0 0.64 9.7 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 XP_011276803.1 - 0.0014 18.5 0.0 1.6 8.5 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA PF00004.24 XP_011276803.1 - 0.0018 18.4 0.0 2.5 8.3 0.0 2.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 XP_011276803.1 - 0.0021 18.1 0.0 1.2 9.0 0.0 3.6 3 0 0 3 3 3 1 AAA ATPase domain AAA_13 PF13166.1 XP_011276803.1 - 0.0029 16.1 1.9 0.4 9.0 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.1 XP_011276803.1 - 0.0037 17.1 0.1 0.69 9.8 0.0 3.2 3 0 0 3 3 2 1 AAA domain Arch_ATPase PF01637.13 XP_011276803.1 - 0.0054 16.4 0.2 4.7 6.8 0.0 2.9 3 0 0 3 3 3 0 Archaeal ATPase SbcCD_C PF13558.1 XP_011276803.1 - 0.0056 16.5 0.0 4.3 7.3 0.0 3.2 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ABC_ATPase PF09818.4 XP_011276803.1 - 0.0085 14.7 0.4 0.052 12.1 0.0 2.4 2 1 0 2 2 2 1 Predicted ATPase of the ABC class AAA_30 PF13604.1 XP_011276803.1 - 0.016 14.7 0.1 7.1 6.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 XP_011276803.1 - 0.025 13.5 0.1 3.5 6.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Dynamin_N PF00350.18 XP_011276803.1 - 0.028 14.2 0.1 1.6 8.5 0.0 2.8 3 0 0 3 3 2 0 Dynamin family Zeta_toxin PF06414.7 XP_011276803.1 - 0.031 13.3 0.2 3.6 6.6 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin DUF3584 PF12128.3 XP_011276803.1 - 0.032 11.5 1.1 2.4 5.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) AAA_25 PF13481.1 XP_011276803.1 - 0.043 13.2 0.0 9.9 5.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 XP_011276803.1 - 0.045 13.1 0.0 9.9 5.5 0.0 2.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Thymidylate_kin PF02223.12 XP_011276803.1 - 0.045 13.1 0.1 0.57 9.5 0.0 2.5 2 0 0 2 2 2 0 Thymidylate kinase MutS_V PF00488.16 XP_011276803.1 - 0.065 12.6 0.2 12 5.1 0.0 2.3 2 0 0 2 2 2 0 MutS domain V PduV-EutP PF10662.4 XP_011276803.1 - 0.066 12.6 0.1 8.7 5.8 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FtsK_SpoIIIE PF01580.13 XP_011276803.1 - 0.072 12.5 0.1 9.1 5.6 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family UME PF08064.8 XP_011276803.1 - 0.076 12.9 0.7 13 5.7 0.0 2.9 2 1 0 2 2 2 0 UME (NUC010) domain NTPase_1 PF03266.10 XP_011276803.1 - 0.093 12.4 0.1 10 5.7 0.0 2.7 3 0 0 3 3 2 0 NTPase ABC_tran_2 PF12848.2 XP_011276803.1 - 0.63 9.9 6.0 0.48 10.2 0.3 2.8 2 0 0 2 2 2 0 ABC transporter GRP PF07172.6 XP_011276803.1 - 1.5 9.3 9.6 5.3 7.5 6.6 1.9 1 0 0 1 1 1 0 Glycine rich protein family AAA_5 PF07728.9 XP_011276804.1 - 2.2e-126 416.2 5.1 2.8e-22 78.9 0.0 9.8 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 XP_011276804.1 - 2.9e-31 107.7 0.0 1e-09 38.0 0.0 8.3 8 0 0 8 8 8 4 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 XP_011276804.1 - 4.9e-27 94.7 2.2 0.00016 21.8 0.0 7.4 7 0 0 7 7 6 5 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 XP_011276804.1 - 8.8e-24 84.1 4.2 0.00015 21.8 0.0 7.7 7 0 0 7 7 7 4 Sigma-54 interaction domain Sigma54_activat PF00158.21 XP_011276804.1 - 2.5e-20 72.6 0.9 0.0011 18.4 0.0 6.3 7 0 0 7 7 5 5 Sigma-54 interaction domain AAA_22 PF13401.1 XP_011276804.1 - 1e-19 70.9 9.5 0.0027 17.8 0.0 8.5 7 2 0 7 7 6 4 AAA domain AAA_14 PF13173.1 XP_011276804.1 - 2.3e-19 69.5 2.6 0.0026 17.6 0.0 8.5 8 1 1 9 9 8 5 AAA domain AAA_33 PF13671.1 XP_011276804.1 - 1.8e-18 66.7 0.7 0.0037 17.1 0.0 7.2 6 1 0 6 6 6 4 AAA domain T2SE PF00437.15 XP_011276804.1 - 1.7e-17 63.2 8.4 0.0027 16.6 0.0 6.3 6 0 0 6 6 6 4 Type II/IV secretion system protein AAA_16 PF13191.1 XP_011276804.1 - 1.9e-17 63.8 24.1 0.0005 20.1 0.0 8.3 8 0 0 8 8 6 4 AAA ATPase domain AAA_17 PF13207.1 XP_011276804.1 - 1.6e-15 57.9 36.7 0.017 15.9 0.0 10.2 9 1 0 9 9 6 5 AAA domain ABC_tran PF00005.22 XP_011276804.1 - 3.5e-14 53.2 15.6 0.0038 17.5 0.0 8.4 7 0 0 7 7 7 3 ABC transporter UPF0079 PF02367.12 XP_011276804.1 - 1.8e-12 46.9 5.7 0.067 12.8 0.2 6.5 6 0 0 6 6 6 4 Uncharacterised P-loop hydrolase UPF0079 MobB PF03205.9 XP_011276804.1 - 2.2e-12 46.8 4.4 0.086 12.5 0.0 6.9 7 0 0 7 7 6 3 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 XP_011276804.1 - 4.1e-12 46.2 5.5 0.24 11.5 0.0 8.1 7 0 0 7 7 7 2 RNA helicase Miro PF08477.8 XP_011276804.1 - 6.7e-12 45.9 7.4 0.34 11.4 0.0 7.3 6 0 0 6 6 6 2 Miro-like protein AAA_28 PF13521.1 XP_011276804.1 - 2.5e-10 40.5 6.1 0.87 9.5 0.0 7.3 6 0 0 6 6 6 1 AAA domain PduV-EutP PF10662.4 XP_011276804.1 - 3.4e-10 39.5 5.3 0.025 14.0 0.0 6.6 6 0 0 6 6 6 2 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.2 XP_011276804.1 - 5.8e-10 38.7 2.2 0.002 17.2 0.0 5.3 6 0 0 6 6 5 3 P-loop containing dynein motor region D3 AAA_19 PF13245.1 XP_011276804.1 - 6.3e-10 38.6 5.4 0.61 9.8 0.1 5.6 5 0 0 5 5 5 3 Part of AAA domain Mg_chelatase PF01078.16 XP_011276804.1 - 8.6e-10 38.1 0.2 11 5.0 0.0 8.9 10 0 0 10 10 9 0 Magnesium chelatase, subunit ChlI NACHT PF05729.7 XP_011276804.1 - 8.1e-09 35.3 7.7 0.17 11.5 0.1 6.1 7 0 0 7 7 5 3 NACHT domain DUF258 PF03193.11 XP_011276804.1 - 1.8e-08 33.7 14.0 0.36 9.9 0.5 5.9 6 0 0 6 6 6 4 Protein of unknown function, DUF258 AAA_25 PF13481.1 XP_011276804.1 - 2.2e-08 33.7 0.3 0.6 9.4 0.0 5.1 4 0 0 4 4 4 2 AAA domain IstB_IS21 PF01695.12 XP_011276804.1 - 6.3e-08 32.2 0.4 0.19 11.1 0.0 5.6 6 0 0 6 6 6 1 IstB-like ATP binding protein RuvB_N PF05496.7 XP_011276804.1 - 7.8e-08 31.6 1.7 0.31 10.0 0.0 4.6 5 0 0 5 5 5 3 Holliday junction DNA helicase ruvB N-terminus ATP-synt_ab PF00006.20 XP_011276804.1 - 5.9e-07 29.1 0.0 0.98 8.8 0.0 4.3 3 1 0 3 3 3 3 ATP synthase alpha/beta family, nucleotide-binding domain AAA_29 PF13555.1 XP_011276804.1 - 6.8e-07 28.7 4.3 1.9 8.0 0.0 6.0 6 0 0 6 6 6 1 P-loop containing region of AAA domain SRP54 PF00448.17 XP_011276804.1 - 5.7e-06 25.9 11.8 0.4 10.0 0.2 6.0 7 0 0 7 7 6 2 SRP54-type protein, GTPase domain AAA_18 PF13238.1 XP_011276804.1 - 2.7e-05 24.4 0.3 0.0019 18.5 0.0 11.2 9 2 0 9 9 6 3 AAA domain NTPase_1 PF03266.10 XP_011276804.1 - 0.0012 18.5 7.3 0.55 9.9 0.3 5.0 4 0 0 4 4 4 1 NTPase FtsK_SpoIIIE PF01580.13 XP_011276804.1 - 0.0014 18.1 3.3 11 5.4 0.0 5.7 6 0 0 6 6 6 0 FtsK/SpoIIIE family AAA_6 PF12774.2 XP_011276804.1 - 0.13 11.7 0.0 1e+02 2.2 0.0 4.5 5 1 0 5 5 5 0 Hydrolytic ATP binding site of dynein motor region D1 Snf7 PF03357.16 XP_011276805.1 - 7.7e-14 51.4 7.1 7.7e-14 51.4 4.9 1.2 1 1 0 1 1 1 1 Snf7 FKBP_C PF00254.23 XP_011276805.1 - 0.022 14.7 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 FKBP-type peptidyl-prolyl cis-trans isomerase Pyocin_S PF06958.7 XP_011276805.1 - 0.087 13.1 0.1 0.17 12.2 0.1 1.4 1 0 0 1 1 1 0 S-type Pyocin Prominin PF05478.6 XP_011276805.1 - 0.33 8.4 2.3 0.39 8.1 1.6 1.0 1 0 0 1 1 1 0 Prominin EAF PF09816.4 XP_011276806.1 - 2.7e-14 53.0 0.3 1.6e-13 50.5 0.2 2.4 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor TFIIA PF03153.8 XP_011276806.1 - 0.096 12.5 34.1 0.14 11.9 23.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TPR_MLP1_2 PF07926.7 XP_011276807.1 - 0.012 15.3 0.0 0.017 14.8 0.0 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein AKNA PF12443.3 XP_011276807.1 - 0.019 14.9 0.5 0.028 14.4 0.3 1.3 1 0 0 1 1 1 0 AT-hook-containing transcription factor Fib_alpha PF08702.5 XP_011276807.1 - 0.03 14.4 1.2 0.055 13.5 0.8 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Tropomyosin PF00261.15 XP_011276807.1 - 0.032 13.3 1.0 0.051 12.6 0.7 1.2 1 0 0 1 1 1 0 Tropomyosin FlaC_arch PF05377.6 XP_011276807.1 - 0.085 12.7 1.0 0.17 11.8 0.7 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) RRF_GI PF12614.3 XP_011276807.1 - 0.092 12.5 1.1 0.11 12.2 0.3 1.4 2 0 0 2 2 2 0 Ribosome recycling factor EF1G PF00647.14 XP_011276807.1 - 0.15 11.7 0.5 0.26 11.0 0.1 1.6 2 0 0 2 2 2 0 Elongation factor 1 gamma, conserved domain NADH_dh_m_C1 PF15088.1 XP_011276807.1 - 0.16 11.5 0.7 0.29 10.6 0.5 1.4 1 0 0 1 1 1 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial TMF_DNA_bd PF12329.3 XP_011276807.1 - 0.19 11.5 3.7 0.36 10.6 2.6 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF4599 PF15371.1 XP_011276807.1 - 0.3 11.1 1.1 6.3 6.9 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4599) Prefoldin PF02996.12 XP_011276807.1 - 0.39 10.3 3.2 0.23 11.1 0.9 1.5 2 0 0 2 2 2 0 Prefoldin subunit FliD_N PF02465.13 XP_011276807.1 - 0.5 10.7 3.6 0.17 12.2 0.7 1.5 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Laminin_II PF06009.7 XP_011276807.1 - 1.3 8.7 5.7 0.21 11.3 1.2 1.6 2 0 0 2 2 2 0 Laminin Domain II DUF904 PF06005.7 XP_011276807.1 - 2.9 8.2 6.0 1.9 8.8 1.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Cpn60_TCP1 PF00118.19 XP_011276808.1 - 6e-147 490.1 9.1 6.9e-147 489.9 6.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FAM176 PF14851.1 XP_011276809.1 - 0.03 14.0 1.8 0.044 13.4 1.3 1.3 1 0 0 1 1 1 0 FAM176 family WD40 PF00400.27 XP_011276810.1 - 7.2e-42 139.8 5.8 2.8e-11 42.8 0.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 XP_011276810.1 - 1e-10 40.4 9.0 0.0003 19.0 0.3 4.3 3 1 0 3 3 3 3 Nucleoporin Nup120/160 DUF3249 PF11615.3 XP_011276810.1 - 0.0017 18.0 0.3 0.01 15.5 0.1 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF3249) V_ATPase_I PF01496.14 XP_011276810.1 - 4.6 4.9 14.6 7.2 4.3 10.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DASH_Spc34 PF08657.5 XP_011276811.1 - 6.8e-07 29.2 8.3 7.3e-07 29.1 5.8 1.0 1 0 0 1 1 1 1 DASH complex subunit Spc34 SlyX PF04102.7 XP_011276811.1 - 0.038 14.3 3.2 0.25 11.7 0.2 2.1 2 0 0 2 2 2 0 SlyX DUF1829 PF08862.5 XP_011276811.1 - 0.07 13.4 0.2 0.087 13.1 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF1829 TMF_DNA_bd PF12329.3 XP_011276811.1 - 0.076 12.8 10.0 0.075 12.8 0.6 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Cep57_MT_bd PF06657.8 XP_011276811.1 - 0.14 12.1 6.2 0.28 11.1 4.0 1.7 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Lzipper-MIP1 PF14389.1 XP_011276811.1 - 0.18 11.8 5.6 0.23 11.5 3.9 1.2 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 DUF4200 PF13863.1 XP_011276811.1 - 0.19 11.6 8.0 0.23 11.3 0.2 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) DASH_Spc34 PF08657.5 XP_011276812.1 - 2.9e-24 86.1 6.8 4.6e-24 85.4 4.7 1.3 1 1 0 1 1 1 1 DASH complex subunit Spc34 Cep57_MT_bd PF06657.8 XP_011276812.1 - 0.036 13.9 0.6 0.12 12.3 0.1 2.0 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 XendoU PF09412.5 XP_011276812.1 - 0.14 11.1 2.4 0.21 10.5 1.7 1.3 1 0 0 1 1 1 0 Endoribonuclease XendoU DUF2570 PF10828.3 XP_011276812.1 - 0.44 10.1 6.2 0.66 9.6 4.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) DUF4526 PF15029.1 XP_011276813.1 - 0.048 13.2 0.9 0.055 13.0 0.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4526) Phage_Coat_A PF05357.8 XP_011276813.1 - 0.2 11.2 3.0 0.38 10.3 2.1 1.5 1 1 0 1 1 1 0 Phage Coat Protein A HNF_C PF09354.5 XP_011276813.1 - 0.84 10.8 4.6 1.4 10.1 3.2 1.4 1 0 0 1 1 1 0 HNF3 C-terminal domain Peptidase_M22 PF00814.20 XP_011276814.1 - 4.6e-85 285.3 0.0 5.5e-85 285.1 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Staygreen PF12638.2 XP_011276814.1 - 0.057 12.9 0.0 1.2 8.6 0.0 2.2 2 0 0 2 2 2 0 Staygreen protein Glutaredoxin PF00462.19 XP_011276815.1 - 1e-13 51.0 0.1 2.3e-13 49.8 0.0 1.7 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin_9 PF14595.1 XP_011276815.1 - 0.0069 15.9 0.1 0.013 15.0 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin TP53IP5 PF15331.1 XP_011276815.1 - 0.018 14.9 0.8 0.027 14.4 0.6 1.2 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Adeno_IVa2 PF02456.10 XP_011276815.1 - 0.027 13.1 0.2 0.037 12.6 0.1 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein ABC2_membrane_3 PF12698.2 XP_011276815.1 - 0.079 11.9 8.7 0.13 11.2 6.0 1.3 1 1 0 1 1 1 0 ABC-2 family transporter protein Cupin_5 PF06172.6 XP_011276816.1 - 1.3e-31 109.3 0.0 3e-31 108.2 0.0 1.5 1 1 0 1 1 1 1 Cupin superfamily (DUF985) Ribosomal_S17 PF00366.15 XP_011276817.1 - 2.2e-30 104.4 1.8 3.4e-30 103.8 1.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 Myb_DNA-binding PF00249.26 XP_011276818.1 - 1.8e-18 66.3 10.9 2.7e-10 40.1 0.2 4.3 5 0 0 5 5 5 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 XP_011276818.1 - 4.5e-18 65.1 6.0 3.8e-13 49.3 1.3 3.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 XP_011276818.1 - 0.0051 16.9 0.8 0.0051 16.9 0.5 4.6 4 1 0 4 4 4 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.4 XP_011276818.1 - 0.061 13.5 10.9 0.11 12.7 0.6 4.5 3 1 1 4 4 4 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Glyco_hydro_2_C PF02836.12 XP_011276819.1 - 0.049 12.5 0.0 0.091 11.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Vps54 PF07928.7 XP_011276820.1 - 0.0001 22.4 0.5 0.0001 22.4 0.4 3.0 3 1 0 3 3 3 1 Vps54-like protein PACT_coil_coil PF10495.4 XP_011276820.1 - 0.047 13.6 0.9 0.17 11.8 0.1 2.3 2 0 0 2 2 2 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein DUF1752 PF08550.5 XP_011276821.1 - 4.5e-11 42.1 2.3 9e-11 41.1 1.6 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Lipase_3 PF01764.20 XP_011276822.1 - 6.2e-09 35.6 0.0 2.2e-08 33.7 0.0 1.9 2 0 0 2 2 2 1 Lipase (class 3) Abhydrolase_5 PF12695.2 XP_011276822.1 - 0.0028 17.4 0.0 0.014 15.1 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.7 XP_011276822.1 - 0.028 14.1 0.0 0.052 13.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) DUF2974 PF11187.3 XP_011276822.1 - 0.04 13.2 0.4 2.2 7.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) TPR_6 PF13174.1 XP_011276822.1 - 0.15 12.5 0.1 0.69 10.5 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat CBF PF03914.12 XP_011276823.1 - 1.5e-44 151.3 2.5 1.5e-44 151.3 1.7 2.5 3 0 0 3 3 3 1 CBF/Mak21 family Macoilin PF09726.4 XP_011276826.1 - 7.8 4.6 9.3 9.7 4.3 6.5 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF1690 PF07956.6 XP_011276827.1 - 3.8e-36 124.1 13.2 4.4e-36 123.9 9.2 1.0 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) MeMO_Hyd_G PF02964.11 XP_011276827.1 - 0.095 12.6 3.1 0.2 11.5 2.1 1.5 1 1 0 1 1 1 0 Methane monooxygenase, hydrolase gamma chain YjcZ PF13990.1 XP_011276827.1 - 0.12 11.4 0.3 0.41 9.7 0.1 1.7 1 1 1 2 2 2 0 YjcZ-like protein Fib_alpha PF08702.5 XP_011276827.1 - 0.17 12.0 6.5 0.25 11.4 4.5 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family UCH PF00443.24 XP_011276828.1 - 8.9e-50 169.2 10.5 1.1e-49 168.9 7.2 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 XP_011276828.1 - 1.1e-15 57.9 23.7 5.8e-15 55.5 16.4 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 XP_011276828.1 - 1.4e-12 46.8 0.4 6.3e-12 44.7 0.2 2.2 1 0 0 1 1 1 1 Ubiquitin family CotE PF10628.4 XP_011276828.1 - 0.025 13.9 0.0 0.078 12.3 0.0 1.8 1 0 0 1 1 1 0 Outer spore coat protein E (CotE) Fungal_trans PF04082.13 XP_011276829.1 - 4.4e-18 65.1 13.9 4.4e-18 65.1 9.7 2.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 XP_011276829.1 - 0.004 17.0 10.6 0.004 17.0 7.3 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 XP_011276830.1 - 2e-102 343.1 33.5 2.4e-102 342.8 23.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 XP_011276830.1 - 2.3e-20 72.6 35.5 5.3e-20 71.4 14.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily HA2 PF04408.18 XP_011276830.1 - 0.17 11.9 0.0 0.38 10.7 0.0 1.6 1 0 0 1 1 1 0 Helicase associated domain (HA2) Sugar_tr PF00083.19 XP_011276831.1 - 1.2e-109 366.8 26.6 1.4e-109 366.6 18.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 XP_011276831.1 - 4.3e-27 94.7 25.9 1.5e-24 86.4 10.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 XP_011276831.1 - 0.0033 15.6 0.8 0.0057 14.8 0.6 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector TPR_19 PF14559.1 XP_011276831.1 - 0.16 12.2 0.0 0.26 11.6 0.0 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF998 PF06197.8 XP_011276831.1 - 8.8 5.5 19.7 0.13 11.5 0.3 4.7 3 1 3 6 6 6 0 Protein of unknown function (DUF998) DBD_Tnp_Mut PF03108.10 XP_011276832.1 - 0.021 14.3 0.3 1.1 8.8 0.0 2.9 2 0 0 2 2 2 0 MuDR family transposase zf-CCCH_2 PF14608.1 XP_011276832.1 - 0.078 13.0 0.5 0.15 12.0 0.3 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type YlbD_coat PF14071.1 XP_011276833.1 - 0.015 15.3 3.3 0.015 15.3 2.3 2.3 1 1 0 2 2 2 0 Putative coat protein Mei4 PF13971.1 XP_011276833.1 - 0.018 14.0 1.2 0.021 13.7 0.8 1.2 1 0 0 1 1 1 0 Meiosis-specific protein Mei4 MFS_1 PF07690.11 XP_011276834.1 - 5.9e-14 51.5 29.9 8.5e-14 51.0 20.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily ICMT PF04140.9 XP_011276835.1 - 2.4e-30 104.5 0.6 4.1e-30 103.8 0.4 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 XP_011276835.1 - 4.1e-16 59.0 2.4 4.1e-16 59.0 1.7 1.7 2 0 0 2 2 2 1 Phospholipid methyltransferase NnrU PF07298.6 XP_011276835.1 - 0.00029 20.2 0.2 0.00052 19.4 0.1 1.4 1 0 0 1 1 1 1 NnrU protein DUF1295 PF06966.7 XP_011276835.1 - 0.0025 17.1 0.6 0.0034 16.7 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) DUF3796 PF12676.2 XP_011276835.1 - 0.02 15.1 6.0 0.02 15.1 4.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3796) EF-hand_7 PF13499.1 XP_011276836.1 - 1.1e-28 99.1 11.8 5.5e-14 52.0 0.2 3.3 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 XP_011276836.1 - 1.1e-25 86.9 8.6 3.1e-07 29.2 0.0 5.0 5 1 1 6 6 6 3 EF hand EF-hand_6 PF13405.1 XP_011276836.1 - 7.2e-24 81.4 5.4 2.2e-06 27.0 0.1 5.3 5 1 1 6 6 6 4 EF-hand domain EF-hand_5 PF13202.1 XP_011276836.1 - 9e-18 62.7 10.8 2.2e-05 23.5 0.0 5.3 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.1 XP_011276836.1 - 1e-14 53.8 9.6 0.00019 20.9 0.2 4.3 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.2 XP_011276836.1 - 3.6e-06 26.6 5.2 0.32 10.7 0.0 3.5 2 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 XP_011276836.1 - 3.8e-05 23.5 0.1 0.011 15.6 0.0 2.6 1 1 1 2 2 2 1 EF-hand domain EF-hand_2 PF09068.6 XP_011276836.1 - 0.00011 22.2 0.1 0.64 10.0 0.0 2.4 2 0 0 2 2 2 2 EF hand SPARC_Ca_bdg PF10591.4 XP_011276836.1 - 0.0012 18.8 2.0 0.24 11.4 0.1 3.5 2 2 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region S10_plectin PF03501.10 XP_011276836.1 - 0.0033 17.2 0.0 0.0057 16.4 0.0 1.5 1 0 0 1 1 1 1 Plectin/S10 domain PMBR PF09373.5 XP_011276836.1 - 0.0038 17.1 0.2 4.7 7.3 0.1 4.0 5 0 0 5 5 5 1 Pseudomurein-binding repeat Mad3_BUB1_II PF08171.6 XP_011276836.1 - 0.024 14.5 0.3 0.7 9.8 0.0 2.4 1 1 1 2 2 2 0 Mad3/BUB1 homology region 2 Hyphal_reg_CWP PF11765.3 XP_011276836.1 - 0.039 12.7 0.0 0.051 12.3 0.0 1.2 1 0 0 1 1 1 0 Hyphally regulated cell wall protein N-terminal Lipoprotein_17 PF04200.7 XP_011276836.1 - 0.1 12.7 3.9 0.087 12.9 1.2 2.1 1 1 0 2 2 2 0 Lipoprotein associated domain COQ7 PF03232.8 XP_011276837.1 - 1.2e-75 252.6 0.1 1.6e-75 252.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.12 XP_011276837.1 - 0.068 13.4 0.0 0.52 10.6 0.0 2.1 2 0 0 2 2 2 0 Rubrerythrin IATP PF04568.7 XP_011276837.1 - 0.71 9.9 4.9 5.1 7.1 0.1 3.0 3 1 0 3 3 3 0 Mitochondrial ATPase inhibitor, IATP YTH PF04146.10 XP_011276838.1 - 4.2e-36 123.6 3.0 4.2e-36 123.6 2.1 1.7 2 0 0 2 2 2 1 YT521-B-like domain ELH PF02323.10 XP_011276838.1 - 0.011 14.8 0.6 0.016 14.3 0.1 1.4 2 0 0 2 2 2 0 Egg-laying hormone precursor BAF1_ABF1 PF04684.8 XP_011276838.1 - 5.4 5.7 16.7 8.3 5.1 11.5 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor ABC_tran_2 PF12848.2 XP_011276838.1 - 7.2 6.5 18.4 0.7 9.7 9.4 1.8 2 0 0 2 2 2 0 ABC transporter Lipase_3 PF01764.20 XP_011276839.1 - 1.3e-28 99.3 0.0 1.9e-28 98.8 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) FHA PF00498.21 XP_011276840.1 - 0.00057 19.9 0.4 0.003 17.6 0.0 2.5 3 0 0 3 3 3 1 FHA domain BRCT PF00533.21 XP_011276840.1 - 0.083 13.0 2.3 0.27 11.3 0.0 2.9 3 0 0 3 3 3 0 BRCA1 C Terminus (BRCT) domain VirionAssem_T7 PF11653.3 XP_011276840.1 - 1.8 9.3 12.0 0.12 13.1 1.5 3.1 3 0 0 3 3 3 0 Bacteriophage T7 virion assembly protein RRM_1 PF00076.17 XP_011276841.1 - 2.7e-16 58.9 0.1 4.1e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 XP_011276841.1 - 9.1e-13 47.9 0.0 1.6e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 XP_011276841.1 - 1.9e-07 30.8 0.0 2.7e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 XP_011276841.1 - 0.0061 16.3 0.2 0.0079 16.0 0.1 1.3 1 1 0 1 1 1 1 RNA binding motif Nup35_RRM_2 PF14605.1 XP_011276841.1 - 0.012 15.3 0.0 0.027 14.2 0.0 1.7 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif HMA PF00403.21 XP_011276841.1 - 0.024 14.7 0.0 0.038 14.1 0.0 1.4 1 0 0 1 1 1 0 Heavy-metal-associated domain Bac_surface_Ag PF01103.18 XP_011276842.1 - 2.5e-28 99.5 16.0 3.4e-28 99.0 11.1 1.1 1 0 0 1 1 1 1 Surface antigen Acetyltransf_1 PF00583.19 XP_011276843.1 - 0.098 12.7 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family FAT PF02259.18 XP_011276844.1 - 2.7e-76 256.8 7.5 6.2e-76 255.6 5.2 1.7 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 XP_011276844.1 - 3.4e-27 95.4 0.5 1.5e-26 93.3 0.1 2.4 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 XP_011276844.1 - 4.8e-07 29.1 0.1 1.4e-06 27.5 0.1 1.8 1 0 0 1 1 1 1 FATC domain TPR_11 PF13414.1 XP_011276844.1 - 0.59 9.8 6.4 0.37 10.4 1.0 2.7 2 0 0 2 2 2 0 TPR repeat Band_7 PF01145.20 XP_011276846.1 - 8.1e-28 97.5 5.4 8.1e-28 97.5 3.7 2.0 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 XP_011276846.1 - 0.00064 19.2 0.8 0.0013 18.3 0.6 1.5 1 0 0 1 1 1 1 SPFH domain-Band 7 family PLA2_B PF01735.13 XP_011276847.1 - 4.9e-124 414.1 10.4 9.8e-102 340.6 3.6 2.1 2 0 0 2 2 2 2 Lysophospholipase catalytic domain Voldacs PF03517.8 XP_011276847.1 - 0.062 13.1 8.1 0.17 11.7 5.6 1.8 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling Nro1 PF12753.2 XP_011276847.1 - 0.075 11.9 9.3 0.11 11.3 6.4 1.2 1 0 0 1 1 1 0 Nuclear pore complex subunit Nro1 SDA1 PF05285.7 XP_011276847.1 - 6.6 5.9 13.2 9.5 5.3 9.2 1.1 1 0 0 1 1 1 0 SDA1 RNase_PH PF01138.16 XP_011276848.1 - 4.6e-14 52.8 0.1 6.7e-14 52.3 0.1 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 XP_011276848.1 - 4.6e-05 23.2 0.0 9.7e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 EMP24_GP25L PF01105.19 XP_011276849.1 - 3.4e-12 46.4 1.8 4.5e-12 46.0 1.3 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD WHIM3 PF15614.1 XP_011276849.1 - 0.053 13.3 0.8 4.8 7.0 0.0 2.4 2 1 0 2 2 2 0 WSTF, HB1, Itc1p, MBD9 motif 3 DUF4306 PF14154.1 XP_011276849.1 - 0.43 10.5 0.1 0.43 10.5 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4306) DUF1533 PF07550.6 XP_011276849.1 - 2.6 8.1 6.7 18 5.4 2.4 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1533) PRESAN PF09687.5 XP_011276850.1 - 0.011 15.7 3.1 0.017 15.1 2.1 1.3 1 0 0 1 1 1 0 Plasmodium RESA N-terminal MIF4G_like_2 PF09090.6 XP_011276850.1 - 0.039 13.1 2.7 0.043 13.0 1.8 1.2 1 0 0 1 1 1 0 MIF4G like Muted PF14942.1 XP_011276850.1 - 0.082 12.7 6.0 0.12 12.2 4.2 1.2 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Sec8_exocyst PF04048.9 XP_011276850.1 - 0.13 11.9 4.6 0.22 11.1 2.4 1.9 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain Fib_alpha PF08702.5 XP_011276850.1 - 0.41 10.7 6.7 0.72 9.9 4.7 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family APG6 PF04111.7 XP_011276850.1 - 0.45 9.5 7.2 0.61 9.0 5.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 YlqD PF11068.3 XP_011276850.1 - 0.78 9.7 8.3 1.8 8.6 1.1 2.2 1 1 1 2 2 2 0 YlqD protein Vfa1 PF08432.5 XP_011276850.1 - 2.1 8.3 5.6 1.2 9.0 2.9 1.3 1 1 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DivIC PF04977.10 XP_011276850.1 - 5.4 6.5 10.1 3.4 7.2 0.5 2.5 1 1 1 2 2 2 0 Septum formation initiator DUF2175 PF09943.4 XP_011276850.1 - 5.4 7.1 6.7 2.1 8.4 0.3 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) RINT1_TIP1 PF04437.8 XP_011276851.1 - 6.9e-59 199.6 33.2 1.1e-58 198.9 23.0 1.3 1 0 0 1 1 1 1 RINT-1 / TIP-1 family DUF676 PF05057.9 XP_011276852.1 - 5.6e-55 185.9 0.0 8.8e-55 185.3 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 XP_011276852.1 - 0.0008 19.0 0.0 0.0025 17.4 0.0 1.8 1 1 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.20 XP_011276852.1 - 0.00085 18.9 0.1 0.0027 17.3 0.0 1.8 2 0 0 2 2 2 1 Lipase (class 3) LCAT PF02450.10 XP_011276852.1 - 0.023 13.6 0.0 0.079 11.9 0.0 1.8 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase Abhydrolase_5 PF12695.2 XP_011276852.1 - 0.031 14.0 0.0 0.066 12.9 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family RF-1 PF00472.15 XP_011276853.1 - 1.6e-37 127.7 4.6 3.2e-37 126.7 3.2 1.5 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 XP_011276853.1 - 3.1e-29 101.0 0.1 1.1e-28 99.2 0.0 2.0 2 0 0 2 2 2 1 PCRF domain DUF1241 PF06840.6 XP_011276853.1 - 0.014 14.6 0.6 0.097 11.9 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1241) Pkinase PF00069.20 XP_011276854.1 - 1.2e-66 224.5 0.0 1.4e-66 224.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011276854.1 - 1.1e-28 100.0 0.0 1.3e-28 99.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 XP_011276854.1 - 0.0004 19.4 0.0 0.0011 18.0 0.0 1.6 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 XP_011276854.1 - 0.0019 17.9 0.1 0.0056 16.4 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family DAO PF01266.19 XP_011276855.1 - 5.2e-50 170.3 0.0 5.9e-50 170.1 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 XP_011276855.1 - 8.3e-10 39.0 0.0 1.1e-06 28.9 0.0 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 XP_011276855.1 - 1.1e-06 28.5 0.0 2.9e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.13 XP_011276855.1 - 5.3e-05 23.1 0.0 9.9e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain Pyr_redox PF00070.22 XP_011276855.1 - 0.00046 20.5 0.7 0.0009 19.6 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 XP_011276855.1 - 0.00056 18.4 0.6 0.0014 17.1 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.7 XP_011276855.1 - 0.0019 17.1 0.2 0.004 16.1 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein ApbA PF02558.11 XP_011276855.1 - 0.0036 16.7 0.0 0.0061 16.0 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Thi4 PF01946.12 XP_011276855.1 - 0.004 16.2 0.1 0.011 14.7 0.1 1.7 1 0 0 1 1 1 1 Thi4 family NAD_Gly3P_dh_N PF01210.18 XP_011276855.1 - 0.0045 16.7 0.0 0.0094 15.6 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_2 PF00890.19 XP_011276855.1 - 0.0068 15.3 0.1 0.011 14.6 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 XP_011276855.1 - 0.0082 16.0 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 XP_011276855.1 - 0.013 15.1 0.0 0.025 14.2 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 XP_011276855.1 - 0.032 13.5 0.0 0.061 12.7 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_9 PF13454.1 XP_011276855.1 - 0.038 13.7 0.1 0.18 11.5 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding GMC_oxred_N PF00732.14 XP_011276855.1 - 0.053 12.6 0.0 0.078 12.1 0.0 1.2 1 0 0 1 1 1 0 GMC oxidoreductase AlaDh_PNT_C PF01262.16 XP_011276855.1 - 0.075 12.5 0.0 0.18 11.3 0.0 1.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.14 XP_011276855.1 - 0.1 11.5 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Sel1 PF08238.7 XP_011276856.1 - 0.00051 20.5 1.8 4.2 8.1 0.0 4.3 5 0 0 5 5 5 2 Sel1 repeat TPR_2 PF07719.12 XP_011276856.1 - 0.00053 19.7 0.4 0.63 10.1 0.0 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 XP_011276856.1 - 0.00065 19.2 0.1 0.0022 17.5 0.0 2.0 2 0 0 2 2 2 1 TPR repeat TPR_16 PF13432.1 XP_011276856.1 - 0.0048 17.5 0.0 0.023 15.3 0.0 2.1 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 XP_011276856.1 - 0.03 14.1 0.0 0.44 10.4 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 XP_011276856.1 - 0.051 13.5 0.9 0.32 10.9 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 XP_011276856.1 - 0.079 13.6 0.0 1.8 9.3 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Glyco_transf_22 PF03901.12 XP_011276857.1 - 6e-96 321.9 32.6 7e-96 321.7 22.6 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PMT_2 PF13231.1 XP_011276857.1 - 0.006 16.4 11.2 0.006 16.4 7.8 2.2 2 0 0 2 2 2 2 Dolichyl-phosphate-mannose-protein mannosyltransferase Aldo_ket_red PF00248.16 XP_011276858.1 - 8.6e-48 162.5 0.0 1e-47 162.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Collagen PF01391.13 XP_011276860.1 - 2.8e-12 45.9 55.2 8.1e-07 28.4 20.0 2.3 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) Flocculin_t3 PF13928.1 XP_011276861.1 - 3.7e-22 78.1 47.7 2.8e-13 49.7 12.7 8.1 8 2 1 9 9 9 2 Flocculin type 3 repeat Flocculin_t3 PF13928.1 XP_011276862.1 - 3.6e-36 123.0 184.2 2.4e-12 46.7 13.8 10.7 9 2 1 10 10 10 6 Flocculin type 3 repeat Methyltransf_23 PF13489.1 XP_011276863.1 - 1.5e-12 47.5 0.0 2.2e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 XP_011276863.1 - 6.1e-10 38.8 1.2 1.3e-09 37.8 0.4 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 XP_011276863.1 - 1.9e-09 37.8 0.2 6.6e-09 36.1 0.1 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 XP_011276863.1 - 4.4e-09 36.7 0.1 8.2e-09 35.8 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 XP_011276863.1 - 0.0007 19.9 0.0 0.0016 18.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 XP_011276863.1 - 0.00079 19.9 0.7 0.0039 17.7 0.1 2.3 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 XP_011276863.1 - 0.0016 17.6 0.0 0.0025 16.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 XP_011276863.1 - 0.018 15.0 0.0 0.084 12.9 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain HEAT PF02985.17 XP_011276865.1 - 0.083 13.0 0.1 13 6.1 0.0 3.3 3 0 0 3 3 3 0 HEAT repeat NGP1NT PF08153.7 XP_011276866.1 - 1.4e-51 173.7 1.0 2.5e-51 173.0 0.7 1.4 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 XP_011276866.1 - 8.9e-21 74.0 0.0 2.9e-15 56.2 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 XP_011276866.1 - 2.1e-05 23.8 0.0 0.00019 20.7 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 XP_011276866.1 - 6.5e-05 22.8 5.5 0.13 12.0 1.5 4.3 3 1 0 3 3 3 2 Dynamin family GTP_EFTU PF00009.22 XP_011276866.1 - 0.00049 19.5 0.0 0.085 12.2 0.0 3.2 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain Arf PF00025.16 XP_011276866.1 - 0.0011 18.2 0.1 0.66 9.1 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family DUF258 PF03193.11 XP_011276866.1 - 0.0054 15.9 0.0 0.011 14.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SusD-like_3 PF14322.1 XP_011276866.1 - 0.089 12.8 0.8 0.14 12.2 0.0 1.7 2 0 0 2 2 2 0 Starch-binding associating with outer membrane RRM_1 PF00076.17 XP_011276867.1 - 0.00034 20.1 0.0 0.14 11.7 0.0 2.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 XP_011276867.1 - 0.0016 18.3 0.1 0.0084 16.0 0.1 2.2 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 XP_011276867.1 - 0.016 15.0 0.2 0.16 11.8 0.2 2.5 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fig1 PF12351.3 XP_011276868.1 - 0.00028 20.8 2.3 0.00034 20.5 1.6 1.1 1 0 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 PGP_phosphatase PF09419.5 XP_011276869.1 - 4.3e-66 221.4 0.0 5.3e-66 221.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 XP_011276869.1 - 8e-07 28.6 0.0 1.4e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 XP_011276869.1 - 0.0048 17.3 0.0 0.0078 16.6 0.0 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 XP_011276869.1 - 0.1 12.8 0.2 0.5 10.5 0.0 1.9 1 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase zf-C3HC4_3 PF13920.1 XP_011276870.1 - 8.6e-05 22.1 9.0 8.6e-05 22.1 6.3 3.7 3 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2_jaz PF12171.3 XP_011276870.1 - 0.035 14.2 0.9 0.035 14.2 0.6 6.6 8 0 0 8 8 8 0 Zinc-finger double-stranded RNA-binding Siva PF05458.7 XP_011276870.1 - 0.29 10.6 5.1 1 8.8 1.6 2.3 2 0 0 2 2 2 0 Cd27 binding protein (Siva) Pex2_Pex12 PF04757.9 XP_011276871.1 - 3.2e-37 128.1 5.2 4.3e-37 127.7 3.6 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.1 XP_011276871.1 - 5.5e-09 35.7 14.3 8.6e-09 35.0 9.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 XP_011276871.1 - 7.8e-09 35.4 14.6 1.3e-08 34.7 10.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 XP_011276871.1 - 1.9e-08 33.8 10.0 2.7e-08 33.3 6.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 XP_011276871.1 - 6.7e-07 28.8 12.5 1.1e-06 28.1 8.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 XP_011276871.1 - 7.7e-06 25.6 12.3 1.5e-05 24.8 8.5 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING U-box PF04564.10 XP_011276871.1 - 3.6e-05 23.6 0.9 0.0087 16.0 0.0 2.4 2 0 0 2 2 2 1 U-box domain zf-RING_5 PF14634.1 XP_011276871.1 - 7.1e-05 22.4 10.0 0.00013 21.6 6.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 XP_011276871.1 - 0.0019 18.2 7.6 0.0037 17.3 5.3 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 XP_011276871.1 - 0.015 15.0 4.2 0.015 15.0 2.9 3.1 3 0 0 3 3 3 0 RING-type zinc-finger MscS_TM PF12794.2 XP_011276871.1 - 0.017 13.7 0.1 0.027 13.1 0.1 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 zf-RING_6 PF14835.1 XP_011276871.1 - 0.067 12.9 5.5 0.13 12.0 3.8 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 XP_011276871.1 - 0.27 11.0 4.4 0.44 10.4 3.1 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 XP_011276871.1 - 0.97 9.0 10.2 1.8 8.1 7.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain IBR PF01485.16 XP_011276871.1 - 1 9.2 10.3 2.6 7.9 7.2 1.6 1 1 0 1 1 1 0 IBR domain zf-B_box PF00643.19 XP_011276871.1 - 5.3 7.0 9.4 3.7 7.5 4.7 2.0 1 1 1 2 2 2 0 B-box zinc finger Fungal_trans PF04082.13 XP_011276872.1 - 9.5e-19 67.2 8.2 3.1e-18 65.5 5.4 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 XP_011276872.1 - 1.2e-08 34.7 11.1 2.2e-08 33.8 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 XP_011276872.1 - 0.16 10.5 9.0 0.0067 15.0 1.3 2.0 2 0 0 2 2 2 0 Fungal specific transcription factor domain PAT1 PF09770.4 XP_011276872.1 - 0.18 10.0 44.5 0.27 9.4 30.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Sugar_tr PF00083.19 XP_011276873.1 - 1.8e-153 511.3 35.2 2.1e-153 511.1 24.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 XP_011276873.1 - 5.3e-28 97.7 36.5 9.8e-28 96.8 21.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily LMF1 PF06762.9 XP_011276873.1 - 0.0062 15.3 0.3 0.0062 15.3 0.2 1.8 2 0 0 2 2 2 1 Lipase maturation factor NADH-u_ox-rdase PF10785.4 XP_011276873.1 - 6.2 7.1 8.5 2.8 8.2 0.7 3.6 2 2 0 2 2 2 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Sugar_tr PF00083.19 XP_011276874.1 - 3.1e-160 533.6 38.7 3.5e-160 533.4 26.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 XP_011276874.1 - 6.7e-30 103.9 35.2 6.7e-30 103.9 24.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 XP_011276874.1 - 0.001 17.5 7.6 0.001 17.5 5.3 3.7 2 2 0 3 3 3 2 MFS/sugar transport protein DUF1462 PF07315.6 XP_011276875.1 - 0.025 14.5 0.0 0.083 12.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1462) tRNA-synt_1d PF00750.14 XP_011276876.1 - 4.3e-100 334.9 1.6 5.9e-100 334.5 1.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 XP_011276876.1 - 6.5e-31 106.7 0.3 2.7e-29 101.5 0.1 2.6 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 XP_011276876.1 - 4.3e-07 30.3 0.0 1.5e-06 28.6 0.0 2.0 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain Fcf1 PF04900.7 XP_011276877.1 - 4.2e-39 132.7 0.2 5.3e-39 132.3 0.1 1.1 1 0 0 1 1 1 1 Fcf1 MoCF_biosynth PF00994.19 XP_011276879.1 - 1.8e-54 183.0 0.0 1.3e-27 96.0 0.0 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.12 XP_011276879.1 - 7.4e-39 132.6 0.2 1.1e-38 132.1 0.2 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 XP_011276879.1 - 2.3e-14 53.0 0.1 9.3e-14 51.1 0.0 2.1 2 0 0 2 2 2 1 MoeA C-terminal region (domain IV) Metallophos PF00149.23 XP_011276880.1 - 5.3e-08 32.5 1.4 2.3e-07 30.4 0.2 2.2 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 XP_011276880.1 - 0.00052 19.8 0.0 0.00098 18.9 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PINIT PF14324.1 XP_011276881.1 - 4.8e-35 120.7 0.2 4.8e-35 120.7 0.1 3.8 3 1 0 3 3 3 1 PINIT domain zf-MIZ PF02891.15 XP_011276881.1 - 1.7e-18 65.8 2.9 3.1e-18 64.9 2.0 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 XP_011276881.1 - 3.2e-06 26.5 0.7 8.1e-06 25.2 0.5 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.22 XP_011276881.1 - 0.023 14.1 0.1 0.04 13.4 0.1 1.4 1 0 0 1 1 1 0 SAP domain zf-C3HC4_4 PF15227.1 XP_011276881.1 - 0.11 12.3 3.0 0.23 11.3 2.1 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 XP_011276881.1 - 0.24 11.0 1.4 0.47 10.1 1.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 XP_011276881.1 - 0.33 10.9 2.5 0.61 10.1 1.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DNA_pol_B PF00136.16 XP_011276882.1 - 7e-148 493.2 2.3 1e-147 492.7 1.6 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 XP_011276882.1 - 3.8e-84 282.3 0.0 7.5e-84 281.3 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 XP_011276882.1 - 4.6e-23 81.0 4.2 9.7e-23 79.9 2.9 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_exo2 PF10108.4 XP_011276882.1 - 0.018 14.6 0.0 0.034 13.6 0.0 1.5 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 XP_011276882.1 - 0.032 14.0 0.2 0.19 11.5 0.2 2.4 1 1 0 1 1 1 0 RNase_H superfamily zf-RING-like PF08746.6 XP_011276882.1 - 0.079 12.9 1.1 0.29 11.1 0.8 2.0 1 0 0 1 1 1 0 RING-like domain C1_1 PF00130.17 XP_011276882.1 - 0.23 11.2 8.2 0.55 9.9 0.7 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) LRR_7 PF13504.1 XP_011276885.1 - 0.022 14.9 11.7 52 4.7 0.0 9.1 12 0 0 12 12 12 0 Leucine rich repeat LRR_1 PF00560.28 XP_011276885.1 - 0.15 12.1 6.6 28 5.2 0.1 5.7 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.1 XP_011276885.1 - 0.82 9.9 15.2 16 5.9 0.1 7.2 8 0 0 8 8 8 0 Leucine Rich repeat LRR_7 PF13504.1 XP_011276886.1 - 0.064 13.4 11.5 36 5.1 0.1 6.8 6 0 0 6 6 6 0 Leucine rich repeat DUF3725 PF12523.3 XP_011276886.1 - 0.069 13.2 0.1 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3725) LRR_8 PF13855.1 XP_011276886.1 - 0.21 11.3 0.1 0.21 11.3 0.0 8.1 8 3 1 9 9 9 0 Leucine rich repeat LRR_1 PF00560.28 XP_011276886.1 - 0.44 10.7 20.8 0.52 10.5 0.3 6.9 6 2 0 6 6 6 0 Leucine Rich Repeat LRR_4 PF12799.2 XP_011276886.1 - 0.48 10.1 35.7 1.6 8.4 0.5 8.5 6 2 3 9 9 9 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 XP_011276887.1 - 2.4 7.9 25.7 1.4 8.7 0.2 6.3 5 2 2 7 7 7 0 Leucine rich repeat SURF1 PF02104.10 XP_011276888.1 - 9.4e-57 192.2 0.0 1.5e-56 191.5 0.0 1.3 1 0 0 1 1 1 1 SURF1 family DUF4059 PF13268.1 XP_011276888.1 - 0.15 12.3 0.2 30 4.9 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4059) Sugar_tr PF00083.19 XP_011276889.1 - 1.9e-90 303.6 22.3 2.3e-90 303.3 15.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 XP_011276889.1 - 1.2e-22 80.0 16.8 2.2e-21 75.9 8.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 XP_011276890.1 - 1.9e-45 155.1 53.4 1.4e-43 148.9 37.8 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 XP_011276890.1 - 8.4e-15 53.9 27.7 1.1e-14 53.5 19.2 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 XP_011276890.1 - 3.1e-14 52.4 17.1 3.1e-14 52.4 11.8 4.2 3 1 1 4 4 4 1 Sugar (and other) transporter Neurensin PF14927.1 XP_011276890.1 - 0.51 9.7 4.9 0.96 8.8 0.0 3.2 3 1 0 3 3 3 0 Neurensin Malic_M PF03949.10 XP_011276891.1 - 1.2e-72 244.4 0.0 1.7e-72 244.0 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 XP_011276891.1 - 4.2e-62 208.9 0.0 7.1e-62 208.2 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Gly_transf_sug PF04488.10 XP_011276892.1 - 1.4e-14 54.3 0.1 2.8e-14 53.3 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 XP_011276892.1 - 0.015 13.8 1.1 2.1 6.7 0.0 2.7 3 0 0 3 3 3 0 TcdA/TcdB catalytic glycosyltransferase domain Glyco_transf_28 PF03033.15 XP_011276892.1 - 0.046 13.4 0.0 0.081 12.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain Ras PF00071.17 XP_011276893.1 - 1.2e-48 164.5 0.0 1.7e-48 164.0 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 XP_011276893.1 - 1.2e-20 74.2 0.7 3.7e-20 72.5 0.0 2.1 3 0 0 3 3 3 1 Miro-like protein GTP_EFTU PF00009.22 XP_011276893.1 - 2.1e-08 33.8 0.1 6.6e-08 32.2 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.16 XP_011276893.1 - 8.1e-07 28.4 0.0 1.2e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 XP_011276893.1 - 8.1e-05 22.5 0.0 0.00016 21.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 XP_011276893.1 - 0.097 11.3 0.0 0.097 11.3 0.0 3.4 2 2 0 3 3 3 0 G-protein alpha subunit DUF3753 PF12575.3 XP_011276893.1 - 0.16 11.7 0.4 0.41 10.4 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) Lin-8 PF03353.10 XP_011276893.1 - 0.28 10.4 5.9 0.36 10.0 4.1 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Lipase_chap PF03280.9 XP_011276893.1 - 0.61 9.5 4.8 0.23 10.9 1.6 1.5 2 0 0 2 2 2 0 Proteobacterial lipase chaperone protein YqeY PF09424.5 XP_011276894.1 - 9.4e-19 67.6 3.8 1.2e-18 67.3 2.7 1.1 1 0 0 1 1 1 1 Yqey-like protein 5_3_exonuc_N PF02739.11 XP_011276894.1 - 0.011 15.0 0.3 0.013 14.8 0.2 1.2 1 0 0 1 1 1 0 5'-3' exonuclease, N-terminal resolvase-like domain Herpes_BLRF2 PF05812.7 XP_011276894.1 - 0.24 11.2 2.5 0.15 11.8 0.4 1.6 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein F-box PF00646.28 XP_011276895.1 - 0.0022 17.5 1.9 0.042 13.5 0.5 2.7 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 XP_011276895.1 - 0.0087 15.7 0.7 0.024 14.3 0.5 1.8 1 0 0 1 1 1 1 F-box-like GRAB PF10375.4 XP_011276896.1 - 3e-08 32.9 3.4 1.9e-07 30.4 0.3 2.7 2 0 0 2 2 2 1 GRIP-related Arf-binding domain Reo_sigmaC PF04582.7 XP_011276896.1 - 0.0017 17.6 9.4 0.0017 17.6 6.5 3.2 1 1 2 3 3 3 2 Reovirus sigma C capsid protein DUF4200 PF13863.1 XP_011276896.1 - 0.0022 17.9 11.2 0.0022 17.9 7.7 6.3 2 2 4 6 6 6 1 Domain of unknown function (DUF4200) CCDC155 PF14662.1 XP_011276896.1 - 0.0022 17.5 53.5 0.0047 16.5 23.3 4.4 1 1 3 4 4 4 2 Coiled-coil region of CCDC155 IncA PF04156.9 XP_011276896.1 - 0.0071 15.9 24.2 0.0071 15.9 16.8 4.8 2 1 3 5 5 5 3 IncA protein DUF641 PF04859.7 XP_011276896.1 - 0.015 15.0 6.4 0.015 15.0 4.5 5.4 1 1 4 5 5 5 0 Plant protein of unknown function (DUF641) AAA_13 PF13166.1 XP_011276896.1 - 1.7 6.9 79.5 0.05 12.0 25.4 2.5 1 1 1 2 2 2 0 AAA domain ATG16 PF08614.6 XP_011276896.1 - 2 8.2 92.2 0.75 9.5 10.9 4.4 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) RFC1 PF08519.7 XP_011276897.1 - 2.5e-55 186.5 2.3 5.3e-55 185.4 0.0 2.6 3 0 0 3 3 3 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 XP_011276897.1 - 4.6e-14 52.3 0.0 1.3e-13 50.8 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 XP_011276897.1 - 1.9e-11 44.2 0.0 8.9e-11 42.1 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 XP_011276897.1 - 1.6e-09 37.0 0.4 5.2e-07 28.7 0.0 2.3 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 XP_011276897.1 - 1.6e-06 28.9 1.0 1.3e-05 26.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain PTCB-BRCT PF12738.2 XP_011276897.1 - 1.3e-05 24.9 0.0 4.2e-05 23.3 0.0 2.0 1 0 0 1 1 1 1 twin BRCT domain RuvB_N PF05496.7 XP_011276897.1 - 2.5e-05 23.4 0.0 4.2e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 XP_011276897.1 - 4.9e-05 23.4 0.0 0.00015 21.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 XP_011276897.1 - 0.00013 21.9 0.0 0.00039 20.4 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 XP_011276897.1 - 0.00064 19.6 0.0 0.0016 18.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 XP_011276897.1 - 0.0017 18.0 0.0 0.0044 16.7 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 XP_011276897.1 - 0.0063 16.8 0.1 0.0063 16.8 0.0 2.1 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.17 XP_011276897.1 - 0.014 15.5 0.2 0.052 13.7 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA_14 PF13173.1 XP_011276897.1 - 0.019 14.8 0.0 0.069 13.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 XP_011276897.1 - 0.031 12.9 0.5 0.22 10.1 0.0 2.1 2 0 0 2 2 2 0 TIP49 C-terminus NACHT PF05729.7 XP_011276897.1 - 0.05 13.2 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain NTPase_1 PF03266.10 XP_011276897.1 - 0.05 13.3 0.0 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 NTPase AAA_5 PF07728.9 XP_011276897.1 - 0.06 13.0 0.1 0.25 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.17 XP_011276897.1 - 0.063 12.1 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_28 PF13521.1 XP_011276897.1 - 0.14 12.1 0.0 0.14 12.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain Pkinase PF00069.20 XP_011276898.1 - 1.3e-63 214.5 0.0 1.9e-63 214.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011276898.1 - 3.6e-36 124.5 0.0 5.5e-36 123.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 XP_011276898.1 - 6.8e-06 25.2 0.0 1.2e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 XP_011276898.1 - 0.0023 16.8 0.0 0.0045 15.8 0.0 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.18 XP_011276898.1 - 0.0044 16.7 0.0 0.0077 15.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 XP_011276898.1 - 0.0075 15.3 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 XP_011276898.1 - 0.092 12.0 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family PNRC PF15365.1 XP_011276898.1 - 0.094 12.7 0.2 0.094 12.7 0.1 2.1 2 0 0 2 2 2 0 Proline-rich nuclear receptor coactivator G6PD_C PF02781.11 XP_011276899.1 - 3.9e-129 429.6 0.0 4.9e-129 429.3 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 XP_011276899.1 - 9.1e-63 211.7 0.0 1.8e-62 210.8 0.0 1.5 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Zn_clus PF00172.13 XP_011276901.1 - 2.4e-06 27.3 5.7 5.1e-06 26.2 3.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.13 XP_011276902.1 - 1.6e-05 24.6 8.1 2.8e-05 23.9 5.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.13 XP_011276904.1 - 3.4e-06 26.8 5.1 5.3e-06 26.2 3.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 XP_011276904.1 - 1.3 9.2 6.5 2.2 8.4 4.5 1.4 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Zn_clus PF00172.13 XP_011276905.1 - 0.00025 20.8 11.4 0.00043 20.1 7.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Kdo PF06293.9 XP_011276906.1 - 2.4e-05 23.5 0.0 6e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family OPT PF03169.10 XP_011276907.1 - 7.3e-160 533.4 41.8 9.1e-160 533.0 29.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Zn_clus PF00172.13 XP_011276908.1 - 5.5e-06 26.1 8.4 9.6e-06 25.4 5.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 XP_011276908.1 - 1.6e-05 23.9 2.2 2.3e-05 23.3 0.3 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain F-box-like PF12937.2 XP_011276909.1 - 1.8e-05 24.3 0.2 1.8e-05 24.3 0.1 2.3 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 XP_011276909.1 - 0.0036 16.9 0.8 0.0036 16.9 0.5 2.7 3 0 0 3 3 3 1 F-box domain LRR_4 PF12799.2 XP_011276909.1 - 0.28 10.8 32.4 9.4 5.9 1.6 7.8 4 3 1 5 5 5 0 Leucine Rich repeats (2 copies) UBX PF00789.15 XP_011276910.1 - 2e-07 30.9 0.1 7.4e-07 29.1 0.1 2.0 1 0 0 1 1 1 1 UBX domain TUG-UBL1 PF11470.3 XP_011276910.1 - 1.2e-06 28.3 2.2 7.9e-05 22.5 0.0 3.2 2 1 1 3 3 3 2 GLUT4 regulating protein TUG Asparaginase PF00710.15 XP_011276911.1 - 1e-32 113.2 0.0 1.4e-32 112.8 0.0 1.1 1 0 0 1 1 1 1 Asparaginase OKR_DC_1_N PF03709.10 XP_011276911.1 - 0.00016 21.6 0.0 0.0014 18.6 0.0 2.2 2 0 0 2 2 2 1 Orn/Lys/Arg decarboxylase, N-terminal domain Ashwin PF15323.1 XP_011276911.1 - 0.28 11.1 9.6 0.51 10.2 6.7 1.3 1 0 0 1 1 1 0 Developmental protein AATase PF07247.7 XP_011276912.1 - 1.6e-69 234.7 16.1 1.9e-69 234.5 11.2 1.0 1 0 0 1 1 1 1 Alcohol acetyltransferase CSTF2_hinge PF14327.1 XP_011276912.1 - 0.0095 16.0 0.1 0.035 14.2 0.1 2.0 1 1 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 Zn_clus PF00172.13 XP_011276913.1 - 1.6e-08 34.2 13.1 2.7e-08 33.5 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-HC5HC2H PF13771.1 XP_011276913.1 - 0.04 14.0 5.8 0.1 12.7 4.0 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain UNC-79 PF14776.1 XP_011276913.1 - 2.8 6.2 9.3 3.7 5.8 6.4 1.1 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 RTA1 PF04479.8 XP_011276914.1 - 3.3e-50 170.6 9.9 5.7e-50 169.9 6.9 1.3 1 0 0 1 1 1 1 RTA1 like protein DUF2165 PF09933.4 XP_011276914.1 - 0.004 16.8 0.0 0.36 10.5 0.0 2.4 2 0 0 2 2 2 2 Predicted small integral membrane protein (DUF2165) Aa_trans PF01490.13 XP_011276915.1 - 6.2e-27 94.1 37.5 7.8e-27 93.7 26.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein RRM_1 PF00076.17 XP_011276916.1 - 7e-77 253.0 10.9 2.9e-16 58.8 0.1 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 XP_011276916.1 - 1.6e-69 229.7 2.3 1.2e-14 54.0 0.0 5.6 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 XP_011276916.1 - 5.1e-44 147.9 0.2 2.3e-08 33.7 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 XP_011276916.1 - 3.6e-08 33.0 0.7 0.79 9.5 0.0 5.1 6 0 0 6 6 6 3 Nup53/35/40-type RNA recognition motif DUF4140 PF13600.1 XP_011276916.1 - 2.1 8.8 0.0 2.1 8.8 0.0 3.8 4 0 0 4 4 4 0 N-terminal domain of unknown function (DUF4140) Staphopain_pro PF14731.1 XP_011276920.1 - 0.0032 17.2 3.3 0.0069 16.1 2.3 1.5 1 0 0 1 1 1 1 Staphopain proregion Acyltransferase PF01553.16 XP_011276920.1 - 0.052 12.9 0.1 0.12 11.8 0.1 1.6 1 0 0 1 1 1 0 Acyltransferase RUN PF02759.14 XP_011276920.1 - 0.071 12.8 0.2 0.26 11.0 0.1 1.9 1 1 1 2 2 2 0 RUN domain LRR_6 PF13516.1 XP_011276921.1 - 3.4e-06 26.5 27.8 0.32 11.1 0.1 8.8 9 0 0 9 9 9 3 Leucine Rich repeat LRR_4 PF12799.2 XP_011276921.1 - 3.6e-05 23.2 39.6 0.12 12.0 3.0 7.2 4 1 4 8 8 8 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 XP_011276921.1 - 0.0022 17.8 19.9 12 6.4 0.0 8.5 9 0 0 9 9 9 1 Leucine Rich Repeat LRR_8 PF13855.1 XP_011276921.1 - 0.016 14.9 31.6 0.99 9.2 3.1 6.1 4 2 1 5 5 5 0 Leucine rich repeat Cwf_Cwc_15 PF04889.7 XP_011276921.1 - 2.2 7.9 17.5 3 7.4 12.1 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein LRR_7 PF13504.1 XP_011276921.1 - 6.7 7.3 20.3 33 5.3 0.0 8.3 8 3 0 8 8 8 0 Leucine rich repeat Myc_N PF01056.13 XP_011276921.1 - 8.6 5.4 14.5 13 4.8 10.0 1.2 1 0 0 1 1 1 0 Myc amino-terminal region MBF1 PF08523.5 XP_011276922.1 - 2.8e-25 88.1 2.1 2.8e-25 88.1 1.4 2.0 2 0 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 XP_011276922.1 - 6.6e-14 51.4 0.2 1.1e-13 50.7 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.1 XP_011276922.1 - 1.2e-05 25.3 0.0 2.3e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.2 XP_011276922.1 - 2.2e-05 24.4 0.1 3.3e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain MitMem_reg PF13012.1 XP_011276922.1 - 0.057 13.5 0.1 0.48 10.5 0.0 1.9 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function TRAP-gamma PF07074.7 XP_011276922.1 - 0.1 12.0 0.6 0.14 11.6 0.4 1.2 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) DUF383 PF04063.9 XP_011276923.1 - 1.3e-65 220.5 2.6 1e-64 217.6 0.1 2.7 2 1 1 3 3 3 2 Domain of unknown function (DUF383) DUF384 PF04064.8 XP_011276923.1 - 6.7e-22 76.8 0.6 1.6e-21 75.6 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF384) Vpu PF00558.14 XP_011276923.1 - 0.32 10.5 2.7 0.95 9.0 1.8 1.9 1 0 0 1 1 1 0 Vpu protein TFIIF_alpha PF05793.7 XP_011276924.1 - 1.1e-13 50.4 57.8 4.8e-11 41.7 27.9 2.8 1 1 3 4 4 4 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) tRNA-synt_1b PF00579.20 XP_011276925.1 - 2.9e-73 246.5 0.0 3.8e-73 246.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) zf-UBR PF02207.15 XP_011276926.1 - 1.5e-19 69.4 11.4 4.8e-19 67.8 7.9 2.0 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 XP_011276926.1 - 0.0003 20.4 0.1 0.00071 19.2 0.1 1.6 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-RING_2 PF13639.1 XP_011276926.1 - 0.0045 16.7 2.1 0.0045 16.7 1.5 3.6 3 1 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 XP_011276926.1 - 4.9 7.2 12.3 0.14 12.1 1.4 3.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-UBR PF02207.15 XP_011276927.1 - 2.7e-18 65.4 17.1 2.7e-18 65.4 11.8 2.4 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 XP_011276927.1 - 2.4e-09 36.7 0.0 5.2e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-RING_2 PF13639.1 XP_011276927.1 - 2.4e-05 24.0 1.3 2.4e-05 24.0 0.9 2.9 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 XP_011276927.1 - 0.00016 21.2 1.8 0.00056 19.5 1.3 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF2870 PF11069.3 XP_011276927.1 - 0.98 9.4 8.6 0.22 11.5 1.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) UCR_UQCRX_QCR9 PF05365.7 XP_011276928.1 - 4.6e-26 90.2 3.4 5.2e-26 90.0 2.4 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like DUF4325 PF14213.1 XP_011276928.1 - 0.014 14.9 0.2 0.016 14.8 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4325) DUF2404 PF10296.4 XP_011276929.1 - 1.9e-07 31.1 0.0 4.2e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) DUF221 PF02714.10 XP_011276930.1 - 6.6e-90 301.2 21.2 6.6e-90 301.2 14.7 1.9 3 0 0 3 3 3 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 XP_011276930.1 - 9.2e-28 96.7 2.8 9.2e-28 96.7 1.9 2.3 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 XP_011276930.1 - 5.7e-14 51.7 0.3 1.2e-13 50.7 0.2 1.5 1 0 0 1 1 1 1 Phosphate metabolism protein DNA_primase_S PF01896.14 XP_011276930.1 - 0.072 12.8 0.2 1.1 9.0 0.0 2.4 2 1 0 2 2 2 0 Eukaryotic and archaeal DNA primase small subunit IncA PF04156.9 XP_011276930.1 - 0.12 11.9 0.0 0.31 10.6 0.0 1.6 1 0 0 1 1 1 0 IncA protein Glyco_hydro_16 PF00722.16 XP_011276931.1 - 7.2e-48 162.3 3.5 7.2e-48 162.3 2.4 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 DUF605 PF04652.11 XP_011276931.1 - 7.9 5.7 13.1 11 5.3 9.0 1.2 1 0 0 1 1 1 0 Vta1 like zf-Tim10_DDP PF02953.10 XP_011276932.1 - 5.3e-08 32.0 0.1 6.9e-08 31.6 0.1 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Mago-bind PF09282.5 XP_011276933.1 - 3.8e-12 45.5 3.8 3.7e-10 39.1 0.4 2.5 2 0 0 2 2 2 2 Mago binding DUF365 PF04033.7 XP_011276933.1 - 0.071 13.0 1.5 5.6 7.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF365) ICAM_N PF03921.9 XP_011276933.1 - 0.076 12.4 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 Intercellular adhesion molecule (ICAM), N-terminal domain Amino_oxidase PF01593.19 XP_011276934.1 - 6.2e-66 223.3 0.0 2.2e-64 218.2 0.0 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 XP_011276934.1 - 8.4e-14 51.3 0.0 1.6e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 XP_011276934.1 - 1.3e-07 31.8 0.0 0.00063 19.8 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 XP_011276934.1 - 9.8e-07 27.9 0.0 8.2e-05 21.6 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 XP_011276934.1 - 5.9e-06 26.2 0.0 0.00025 21.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 XP_011276934.1 - 2.6e-05 23.2 0.3 3.9e-05 22.6 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 XP_011276934.1 - 4.6e-05 22.6 0.5 8.3e-05 21.8 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 XP_011276934.1 - 5.6e-05 22.4 0.1 0.00011 21.4 0.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 XP_011276934.1 - 0.00088 19.6 2.3 0.0022 18.3 0.4 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 XP_011276934.1 - 0.00091 17.7 3.9 0.0051 15.3 1.1 2.1 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 XP_011276934.1 - 0.0022 16.9 0.8 0.0086 14.9 0.2 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.12 XP_011276934.1 - 0.018 14.1 0.6 0.03 13.4 0.4 1.3 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.16 XP_011276934.1 - 0.026 14.0 0.1 0.066 12.7 0.0 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain L27_2 PF09045.5 XP_011276934.1 - 0.029 13.9 0.0 0.075 12.5 0.0 1.6 1 0 0 1 1 1 0 L27_2 Lycopene_cycl PF05834.7 XP_011276934.1 - 0.047 12.5 0.4 0.41 9.5 0.1 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 XP_011276934.1 - 0.29 10.8 1.6 9 6.0 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding AAA PF00004.24 XP_011276935.1 - 6.7e-12 45.7 0.1 2.4e-11 43.9 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 XP_011276935.1 - 2.8e-07 29.6 0.1 7.4e-05 21.6 0.0 2.7 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 XP_011276935.1 - 1.1e-06 28.8 0.0 6.4e-06 26.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 XP_011276935.1 - 5.2e-06 26.3 0.0 1.6e-05 24.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 XP_011276935.1 - 1.4e-05 24.3 0.0 2.8e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 XP_011276935.1 - 3.5e-05 24.6 3.3 0.00016 22.4 0.4 3.4 3 1 0 3 3 2 1 AAA domain AAA_19 PF13245.1 XP_011276935.1 - 5.4e-05 22.8 0.0 0.00015 21.4 0.0 1.7 2 0 0 2 2 2 1 Part of AAA domain AAA_33 PF13671.1 XP_011276935.1 - 0.00016 21.5 0.0 0.0005 19.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.8 XP_011276935.1 - 0.00041 19.9 0.2 0.0012 18.3 0.1 1.8 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_16 PF13191.1 XP_011276935.1 - 0.003 17.5 0.2 0.038 13.9 0.0 2.6 2 1 1 3 3 2 1 AAA ATPase domain AAA_5 PF07728.9 XP_011276935.1 - 0.0078 15.9 0.0 0.018 14.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 XP_011276935.1 - 0.01 16.1 0.5 0.01 16.1 0.3 3.3 2 1 1 3 3 3 0 AAA domain RNA_helicase PF00910.17 XP_011276935.1 - 0.022 14.9 0.0 0.18 12.0 0.0 2.5 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.17 XP_011276935.1 - 0.022 13.6 0.0 0.048 12.5 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain TIP49 PF06068.8 XP_011276935.1 - 0.023 13.4 0.6 0.45 9.1 0.0 2.4 2 0 0 2 2 2 0 TIP49 C-terminus ABC_tran PF00005.22 XP_011276935.1 - 0.037 14.3 0.0 0.32 11.3 0.0 2.6 2 0 0 2 2 2 0 ABC transporter Thymidylate_kin PF02223.12 XP_011276935.1 - 0.053 12.8 0.0 0.26 10.6 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase AAA_11 PF13086.1 XP_011276935.1 - 0.068 12.7 3.8 0.029 13.9 0.3 2.2 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 XP_011276935.1 - 0.13 11.6 0.0 0.29 10.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein HALZ PF02183.13 XP_011276935.1 - 0.69 9.6 4.9 0.77 9.5 0.0 3.3 4 0 0 4 4 3 0 Homeobox associated leucine zipper CRAL_TRIO PF00650.15 XP_011276936.1 - 1.4e-35 122.0 0.0 1.8e-35 121.7 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 XP_011276936.1 - 0.001 18.9 0.0 0.0019 18.1 0.0 1.3 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain RasGAP PF00616.14 XP_011276937.1 - 1.1e-44 152.4 5.6 1.1e-44 152.4 3.9 2.4 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 XP_011276937.1 - 1.1e-05 25.1 0.0 3.4e-05 23.5 0.0 1.9 1 0 0 1 1 1 1 C2 domain UPF1_Zn_bind PF09416.5 XP_011276938.1 - 4.1e-67 224.5 11.0 4.1e-67 224.5 7.6 2.2 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_11 PF13086.1 XP_011276938.1 - 1.6e-56 191.5 2.6 2.7e-56 190.7 1.8 1.4 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.1 XP_011276938.1 - 5.6e-56 189.0 0.0 1.4e-55 187.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 XP_011276938.1 - 1.4e-13 50.8 0.0 1.5e-12 47.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 XP_011276938.1 - 2.6e-13 49.5 0.0 1e-12 47.6 0.0 1.9 2 0 0 2 2 2 1 Part of AAA domain DUF2075 PF09848.4 XP_011276938.1 - 3.5e-06 26.2 0.0 8e-05 21.7 0.0 2.9 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 XP_011276938.1 - 1.8e-05 24.6 0.1 4.8e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 XP_011276938.1 - 3.8e-05 23.3 0.0 0.5 9.8 0.0 3.5 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.9 XP_011276938.1 - 0.00022 20.9 0.0 0.00043 19.9 0.0 1.5 1 0 0 1 1 1 1 Helicase PIF1 PF05970.9 XP_011276938.1 - 0.0019 17.2 0.2 1.5 7.6 0.0 2.3 1 1 0 2 2 2 2 PIF1-like helicase DEAD PF00270.24 XP_011276938.1 - 0.002 17.6 0.2 0.0043 16.5 0.1 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_16 PF13191.1 XP_011276938.1 - 0.003 17.5 0.2 0.0058 16.6 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain PhoH PF02562.11 XP_011276938.1 - 0.0083 15.3 0.0 0.018 14.2 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein T2SE PF00437.15 XP_011276938.1 - 0.025 13.4 0.0 0.05 12.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.1 XP_011276938.1 - 0.039 14.0 0.0 0.11 12.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.17 XP_011276938.1 - 0.067 12.6 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA PF00004.24 XP_011276938.1 - 0.1 12.8 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) UvrD_C_2 PF13538.1 XP_011276938.1 - 0.14 12.2 0.0 0.39 10.8 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain zf-BED PF02892.10 XP_011276938.1 - 0.31 10.8 8.2 1.4 8.7 5.3 2.4 1 1 0 1 1 1 0 BED zinc finger WSC PF01822.14 XP_011276940.1 - 5.2e-11 42.3 10.2 5.2e-11 42.3 7.1 4.4 2 1 0 2 2 2 1 WSC domain ADH_N PF08240.7 XP_011276941.1 - 2.5e-29 101.2 1.5 4e-29 100.5 0.2 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 XP_011276941.1 - 1.3e-28 99.1 0.6 1.9e-28 98.6 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 XP_011276941.1 - 1.2e-05 26.1 0.1 2.9e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase GST_C PF00043.20 XP_011276942.1 - 3.7e-13 49.2 0.0 7.2e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 XP_011276942.1 - 1.7e-10 40.9 0.0 2.8e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 XP_011276942.1 - 1.7e-08 34.3 0.0 3.1e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 XP_011276942.1 - 2.5e-07 30.7 0.0 4.6e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 XP_011276942.1 - 1.4e-06 28.1 0.0 2.3e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 XP_011276942.1 - 6.4e-06 26.5 0.2 9.6e-06 26.0 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 XP_011276943.1 - 1.6e-13 50.6 0.0 2.8e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 XP_011276943.1 - 4.6e-11 42.5 0.0 8.4e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 XP_011276943.1 - 5.1e-09 36.1 0.0 1.2e-08 35.0 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 XP_011276943.1 - 8.2e-09 35.3 0.1 1.3e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 XP_011276943.1 - 3.6e-07 29.9 0.0 5e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 XP_011276943.1 - 0.00083 19.7 0.1 0.0015 18.9 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 XP_011276944.1 - 2.6e-13 49.7 0.0 4.5e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 XP_011276944.1 - 2.7e-08 33.5 0.0 4.5e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 XP_011276944.1 - 2.4e-07 30.8 0.0 4e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 XP_011276944.1 - 1.9e-06 28.2 0.3 3e-06 27.6 0.2 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 XP_011276944.1 - 0.00058 19.8 0.0 0.0012 18.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Zn_clus PF00172.13 XP_011276945.1 - 4e-08 33.0 14.9 6.3e-08 32.3 10.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 XP_011276946.1 - 3.9e-24 84.9 1.6 3.9e-24 84.9 1.1 3.4 3 0 0 3 3 3 2 Fungal specific transcription factor domain Zn_clus PF00172.13 XP_011276946.1 - 1.2e-08 34.6 12.2 2.6e-08 33.6 8.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mito_carr PF00153.22 XP_011276947.1 - 1e-67 223.8 4.4 1.4e-23 82.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Fork_head PF00250.13 XP_011276948.1 - 6.3e-31 106.2 0.2 1.9e-30 104.7 0.1 1.8 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 XP_011276948.1 - 1.4e-09 37.9 0.1 3.3e-09 36.7 0.1 1.7 1 0 0 1 1 1 1 FHA domain Proteasome PF00227.21 XP_011276949.1 - 2.4e-49 167.2 0.1 2.9e-49 166.9 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit RPAP1_C PF08620.5 XP_011276950.1 - 1.4e-30 104.9 0.0 3.2e-30 103.7 0.0 1.7 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 XP_011276950.1 - 1.4e-13 50.1 5.9 2.7e-13 49.2 4.1 1.5 1 0 0 1 1 1 1 RPAP1-like, N-terminal HEAT PF02985.17 XP_011276950.1 - 0.18 11.9 0.1 1.5 9.0 0.0 2.3 2 0 0 2 2 2 0 HEAT repeat BLOC1_2 PF10046.4 XP_011276951.1 - 0.51 10.5 2.8 0.83 9.8 0.6 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 KH_1 PF00013.24 XP_011276952.1 - 6.6e-41 137.7 3.0 5.5e-14 51.5 0.0 3.1 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 XP_011276952.1 - 2.4e-28 97.2 7.1 4.3e-10 38.9 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 XP_011276952.1 - 5.7e-12 45.0 5.3 0.00047 19.6 0.0 3.7 4 0 0 4 4 4 3 KH domain KH_4 PF13083.1 XP_011276952.1 - 1.5e-08 34.1 1.3 0.053 13.1 0.0 3.6 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 XP_011276952.1 - 3.2e-05 23.6 5.1 0.14 11.9 0.0 3.5 3 0 0 3 3 3 2 NusA-like KH domain CRF PF00473.12 XP_011276952.1 - 0.11 12.6 0.1 0.2 11.7 0.1 1.4 1 0 0 1 1 1 0 Corticotropin-releasing factor family CS PF04969.11 XP_011276954.1 - 1.5e-09 38.2 1.9 2.6e-09 37.5 1.3 1.3 1 0 0 1 1 1 1 CS domain Tash_PEST PF07708.6 XP_011276954.1 - 9 6.3 7.1 33 4.5 1.4 2.7 2 0 0 2 2 2 0 Tash protein PEST motif Med14 PF08638.6 XP_011276955.1 - 1.4e-52 177.8 2.0 3.4e-52 176.5 1.4 1.7 1 0 0 1 1 1 1 Mediator complex subunit MED14 Aldose_epim PF01263.15 XP_011276955.1 - 1.5e-40 139.2 1.2 1.7e-40 138.9 0.2 1.6 2 0 0 2 2 2 1 Aldose 1-epimerase Pkinase PF00069.20 XP_011276956.1 - 1e-57 195.2 0.0 1.3e-57 194.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011276956.1 - 1e-32 113.2 0.0 1.5e-32 112.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 XP_011276956.1 - 0.00015 20.7 0.0 0.00056 18.9 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 XP_011276956.1 - 0.0025 16.8 0.0 0.0046 16.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 XP_011276956.1 - 0.052 13.2 0.0 0.25 11.0 0.0 1.9 2 1 0 2 2 2 0 Phosphotransferase enzyme family CLASP_N PF12348.3 XP_011276958.1 - 6.2e-08 32.2 0.0 9.8e-08 31.6 0.0 1.3 1 0 0 1 1 1 1 CLASP N terminal ADH_N PF08240.7 XP_011276959.1 - 1e-27 96.0 0.0 1.6e-27 95.4 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 XP_011276959.1 - 2.2e-26 91.9 0.1 3.7e-26 91.1 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 XP_011276959.1 - 0.011 15.1 0.1 0.019 14.3 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_3 PF13738.1 XP_011276959.1 - 0.048 13.7 0.3 0.1 12.6 0.2 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 XP_011276959.1 - 0.087 13.2 0.8 0.46 10.9 0.3 2.3 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 XP_011276959.1 - 0.12 11.5 0.1 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Cu-oxidase_2 PF07731.9 XP_011276960.1 - 1.2e-45 154.3 9.7 6.6e-40 135.8 2.3 2.6 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 XP_011276960.1 - 2e-43 146.8 3.9 5.1e-40 135.8 0.4 3.3 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 XP_011276960.1 - 2.5e-35 121.7 4.1 5.7e-31 107.5 0.2 3.3 3 0 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.1 XP_011276960.1 - 0.0016 18.3 0.1 5.7 6.8 0.0 4.0 4 1 0 4 4 4 2 Cupredoxin-like domain GTP_EFTU PF00009.22 XP_011276961.1 - 9.1e-60 201.3 0.3 1.7e-59 200.4 0.2 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 XP_011276961.1 - 1.8e-33 114.6 0.1 5.1e-33 113.1 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.1 XP_011276961.1 - 9.1e-30 102.3 0.0 2e-29 101.2 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 XP_011276961.1 - 2.2e-22 78.7 0.0 4.4e-22 77.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 XP_011276961.1 - 3.1e-12 46.4 0.8 8e-12 45.1 0.1 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 XP_011276961.1 - 0.0081 16.1 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 XP_011276961.1 - 0.047 14.1 0.0 0.14 12.6 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein DUF442 PF04273.8 XP_011276961.1 - 0.067 13.0 0.0 5.6 6.8 0.0 2.9 3 0 0 3 3 3 0 Putative phosphatase (DUF442) MMS1_N PF10433.4 XP_011276962.1 - 2.8e-60 203.8 3.6 4.3e-60 203.2 2.5 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term rRNA_processing PF08524.6 XP_011276963.1 - 8.3e-37 126.2 30.3 9e-37 126.1 21.0 1.0 1 0 0 1 1 1 1 rRNA processing hDGE_amylase PF14701.1 XP_011276963.1 - 0.61 8.9 4.5 0.68 8.7 3.1 1.0 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme RR_TM4-6 PF06459.7 XP_011276963.1 - 2.1 8.1 11.9 2.3 8.0 8.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 BORG_CEP PF14957.1 XP_011276963.1 - 5.4 7.9 7.0 10 7.0 4.8 1.5 1 1 0 1 1 1 0 Cdc42 effector PPR_2 PF13041.1 XP_011276964.1 - 2.3e-14 53.1 10.7 6.7e-06 25.9 0.0 6.6 5 1 1 6 6 6 5 PPR repeat family PPR PF01535.15 XP_011276964.1 - 4.7e-08 32.4 10.7 0.0044 16.9 0.1 7.7 7 1 0 8 8 8 1 PPR repeat PPR_3 PF13812.1 XP_011276964.1 - 9.2e-08 31.7 0.0 0.063 13.5 0.0 6.4 7 0 0 7 7 7 2 Pentatricopeptide repeat domain PPR_1 PF12854.2 XP_011276964.1 - 5.7e-05 22.5 0.0 0.0017 17.7 0.0 3.3 4 0 0 4 4 4 1 PPR repeat Apc3 PF12895.2 XP_011276964.1 - 0.008 16.2 1.4 17 5.6 0.0 4.8 4 1 1 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 Sugar_tr PF00083.19 XP_011276965.1 - 9.1e-71 238.7 12.6 2.2e-70 237.5 8.7 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 XP_011276965.1 - 2e-18 66.2 26.1 4.1e-18 65.2 8.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily SPC22 PF04573.7 XP_011276965.1 - 8.7e-16 57.6 0.1 8.7e-16 57.6 0.0 1.8 2 0 0 2 2 2 1 Signal peptidase subunit Yip1 PF04893.12 XP_011276966.1 - 5.5e-06 25.9 16.1 5.5e-06 25.9 11.2 1.5 1 1 0 1 1 1 1 Yip1 domain Grp1_Fun34_YaaH PF01184.14 XP_011276967.1 - 2.9e-74 248.9 19.1 3.6e-74 248.6 13.2 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family AA_permease PF00324.16 XP_011276968.1 - 1.8e-122 409.1 39.4 2.3e-122 408.7 27.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 XP_011276968.1 - 1.1e-27 96.7 41.4 1.4e-27 96.3 28.7 1.1 1 0 0 1 1 1 1 Amino acid permease Mannosyl_trans3 PF11051.3 XP_011276969.1 - 3.2e-73 246.3 0.1 5.8e-73 245.5 0.0 1.5 2 0 0 2 2 2 1 Mannosyltransferase putative DUF465 PF04325.8 XP_011276969.1 - 0.81 9.4 9.3 11 5.8 0.1 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF465) DnaJ PF00226.26 XP_011276970.1 - 2.9e-16 58.9 1.8 2.9e-16 58.9 1.3 3.6 3 0 0 3 3 3 1 DnaJ domain RCC_reductase PF06405.6 XP_011276971.1 - 0.0089 14.9 0.1 0.017 14.0 0.1 1.4 1 0 0 1 1 1 1 Red chlorophyll catabolite reductase (RCC reductase) ACOX PF01756.14 XP_011276972.1 - 4.9e-41 140.1 0.5 9e-41 139.3 0.1 1.7 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.14 XP_011276972.1 - 3.3e-16 58.5 0.3 5.7e-16 57.7 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.1 XP_011276972.1 - 2.4e-11 44.0 0.0 5.3e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.19 XP_011276972.1 - 6.2e-08 32.8 0.6 0.0003 20.9 0.0 2.7 3 0 0 3 3 3 2 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.6 XP_011276972.1 - 0.069 13.3 0.0 0.35 11.1 0.0 2.1 3 0 0 3 3 3 0 Acyl-CoA dehydrogenase, C-terminal domain DUF1989 PF09347.5 XP_011276973.1 - 1.6e-52 177.2 0.0 2e-52 176.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) Peptidase_C50 PF03568.12 XP_011276974.1 - 6.6e-105 350.9 0.0 6.6e-105 350.9 0.0 4.6 5 1 1 6 6 6 2 Peptidase family C50 Aldedh PF00171.17 XP_011276976.1 - 2.4e-80 270.1 0.0 3.2e-80 269.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Med11 PF10280.4 XP_011276977.1 - 1.8e-19 69.9 3.4 2e-19 69.7 2.3 1.0 1 0 0 1 1 1 1 Mediator complex protein Baculo_PEP_C PF04513.7 XP_011276977.1 - 0.098 12.4 2.2 0.41 10.4 1.4 2.1 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus ING PF12998.2 XP_011276977.1 - 0.11 12.7 5.4 0.079 13.2 0.7 2.2 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Med2 PF11214.3 XP_011276977.1 - 0.36 10.8 6.0 0.16 12.0 1.7 2.0 1 1 1 2 2 2 0 Mediator complex subunit 2 Lipoprotein_20 PF13942.1 XP_011276977.1 - 0.38 10.2 3.2 0.16 11.5 0.6 1.5 2 0 0 2 2 2 0 YfhG lipoprotein CENP-H PF05837.7 XP_011276977.1 - 0.68 10.1 7.5 1.8 8.7 2.0 2.2 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Occludin_ELL PF07303.8 XP_011276977.1 - 3.4 8.4 7.9 1.8 9.3 2.7 2.0 2 0 0 2 2 2 0 Occludin homology domain WD40 PF00400.27 XP_011276978.1 - 7.5e-60 196.8 19.0 3.4e-11 42.5 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 XP_011276978.1 - 9.2e-05 20.7 9.6 0.18 9.9 0.3 4.0 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 XP_011276978.1 - 0.00066 18.0 0.0 0.0057 15.0 0.0 2.2 1 1 2 3 3 3 1 Cytochrome D1 heme domain eIF2A PF08662.6 XP_011276978.1 - 0.0019 17.9 0.2 0.021 14.5 0.0 2.4 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 XP_011276978.1 - 0.02 13.6 4.0 3.2 6.3 0.3 3.5 1 1 3 4 4 4 0 Nup133 N terminal like DUF1513 PF07433.6 XP_011276978.1 - 0.12 11.2 0.1 0.99 8.2 0.0 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1513) Peptidase_M3 PF01432.15 XP_011276979.1 - 7.4e-133 443.9 0.2 9.7e-133 443.5 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.1 XP_011276979.1 - 0.053 12.9 0.1 0.089 12.1 0.1 1.2 1 0 0 1 1 1 0 Peptidase M50B-like TPR_12 PF13424.1 XP_011276980.1 - 2.2e-05 24.3 6.7 0.019 14.8 0.1 3.7 3 2 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 XP_011276980.1 - 0.0014 18.1 4.4 0.95 9.1 0.4 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 XP_011276980.1 - 0.0027 17.3 2.4 0.19 11.3 0.3 2.7 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 XP_011276980.1 - 0.0074 16.1 4.5 0.58 10.2 0.3 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat SNAP PF14938.1 XP_011276980.1 - 0.016 14.3 0.2 0.016 14.3 0.1 2.0 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP TPR_19 PF14559.1 XP_011276980.1 - 0.13 12.6 3.2 5.7 7.3 0.6 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 XP_011276980.1 - 0.2 12.3 3.2 54 4.8 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF159 PF02586.9 XP_011276981.1 - 3e-48 164.1 0.4 5.8e-48 163.1 0.3 1.5 1 0 0 1 1 1 1 Uncharacterised ACR, COG2135 Mur_ligase_M PF08245.7 XP_011276982.1 - 1.3e-05 25.3 0.0 7.4e-05 22.8 0.0 2.2 1 1 0 1 1 1 1 Mur ligase middle domain Chlam_vir PF05475.6 XP_011276982.1 - 0.0052 15.9 3.1 0.006 15.7 1.2 1.8 2 0 0 2 2 2 1 Chlamydia virulence protein PGP3-D Adaptin_N PF01602.15 XP_011276983.1 - 1.2e-114 383.5 19.0 1.8e-114 382.9 13.2 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 XP_011276983.1 - 3.7e-23 82.2 0.7 3.7e-23 82.2 0.5 2.5 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 XP_011276983.1 - 1.6e-13 50.6 0.4 1.8e-05 24.9 0.0 4.5 2 2 2 4 4 4 3 HEAT repeats HEAT PF02985.17 XP_011276983.1 - 7.8e-12 44.2 0.5 0.021 14.8 0.0 5.1 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.1 XP_011276983.1 - 0.00049 20.4 0.1 12 6.5 0.0 5.3 5 1 1 6 6 6 1 HEAT-like repeat Arm PF00514.18 XP_011276983.1 - 0.018 14.8 0.2 0.61 10.0 0.0 3.5 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat CAAP1 PF15335.1 XP_011276983.1 - 0.062 13.5 2.8 0.19 11.9 0.0 3.0 3 0 0 3 3 3 0 Caspase activity and apoptosis inhibitor 1 AA_permease PF00324.16 XP_011276984.1 - 2.7e-120 401.9 40.8 3.4e-120 401.6 28.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 XP_011276984.1 - 2.2e-37 128.6 44.6 2.8e-37 128.3 30.9 1.0 1 0 0 1 1 1 1 Amino acid permease EFF-AFF PF14884.1 XP_011276984.1 - 0.24 9.4 0.7 0.37 8.8 0.5 1.2 1 0 0 1 1 1 0 Type I membrane glycoproteins cell-cell fusogen AA_permease PF00324.16 XP_011276985.1 - 4.9e-118 394.5 41.8 5.9e-118 394.2 29.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 XP_011276985.1 - 8.6e-38 129.9 46.9 1.1e-37 129.6 32.5 1.0 1 0 0 1 1 1 1 Amino acid permease Anp1 PF03452.9 XP_011276986.1 - 4.4e-49 167.0 0.8 4.4e-49 167.0 0.5 1.4 1 1 0 1 1 1 1 Anp1 DNA_Packaging_2 PF11123.3 XP_011276986.1 - 0.47 10.3 4.2 1.3 8.9 0.8 2.8 3 0 0 3 3 3 0 DNA packaging protein Anp1 PF03452.9 XP_011276987.1 - 2.5e-40 138.3 0.1 4.9e-40 137.3 0.0 1.5 1 0 0 1 1 1 1 Anp1 DUF3987 PF13148.1 XP_011276987.1 - 0.56 8.7 10.0 7.2 5.0 5.3 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3987) IncA PF04156.9 XP_011276987.1 - 0.85 9.1 8.2 0.19 11.3 0.7 2.2 2 0 0 2 2 2 0 IncA protein COPIIcoated_ERV PF07970.7 XP_011276988.1 - 5.1e-38 130.9 0.1 7.2e-38 130.4 0.1 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 XP_011276988.1 - 6.4e-16 58.1 1.2 2.8e-15 56.0 0.2 2.4 3 0 0 3 3 3 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF2649 PF10854.3 XP_011276988.1 - 0.021 14.9 0.4 0.051 13.6 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2649) IBR PF01485.16 XP_011276989.1 - 4.3e-14 52.1 37.2 5.1e-09 35.8 3.9 3.8 3 1 1 4 4 4 2 IBR domain zf-RING_2 PF13639.1 XP_011276989.1 - 5.8e-07 29.2 6.5 5.8e-07 29.2 4.5 3.9 3 1 1 4 4 4 1 Ring finger domain zf-RING_5 PF14634.1 XP_011276989.1 - 1.6e-05 24.4 7.6 1.6e-05 24.4 5.3 4.5 3 2 1 4 4 4 1 zinc-RING finger domain zf-C3HC4 PF00097.20 XP_011276989.1 - 4.3e-05 23.0 8.8 4.3e-05 23.0 6.1 4.8 3 2 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 XP_011276989.1 - 0.0005 20.0 7.6 0.0005 20.0 5.3 4.6 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.16 XP_011276989.1 - 0.009 15.8 6.0 0.009 15.8 4.1 3.5 3 0 0 3 3 3 2 FYVE zinc finger RWD PF05773.17 XP_011276989.1 - 0.014 15.2 0.1 0.038 13.8 0.0 1.8 1 0 0 1 1 1 0 RWD domain Baculo_RING PF05883.6 XP_011276989.1 - 0.019 14.8 0.6 0.019 14.8 0.4 2.5 4 0 0 4 4 4 0 Baculovirus U-box/Ring-like domain DUF1699 PF08004.6 XP_011276989.1 - 0.051 13.0 0.3 0.28 10.6 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1699) Rad50_zn_hook PF04423.9 XP_011276989.1 - 8.3 5.9 10.4 23 4.5 0.8 4.4 2 1 2 4 4 4 0 Rad50 zinc hook motif Pex24p PF06398.6 XP_011276990.1 - 1.6e-82 277.1 1.9 2.2e-82 276.7 1.3 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin MHCassoc_trimer PF08831.5 XP_011276990.1 - 0.11 12.4 1.6 0.22 11.3 0.1 2.4 2 0 0 2 2 2 0 Class II MHC-associated invariant chain trimerisation domain Asp_Glu_race PF01177.17 XP_011276991.1 - 4.6e-24 85.5 0.0 5.7e-24 85.2 0.0 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase DUF3949 PF13133.1 XP_011276993.1 - 0.29 11.3 1.7 4.7 7.5 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3949) ATP-synt_8 PF00895.15 XP_011276993.1 - 6.7 7.0 10.2 0.36 11.0 0.9 2.4 1 1 1 2 2 2 0 ATP synthase protein 8 WSC PF01822.14 XP_011276994.1 - 1.1e-11 44.4 15.6 1.1e-11 44.4 10.8 3.2 2 1 0 2 2 2 1 WSC domain DUF605 PF04652.11 XP_011276994.1 - 0.00014 21.4 13.0 0.00018 21.0 9.0 1.2 1 0 0 1 1 1 1 Vta1 like TMEM154 PF15102.1 XP_011276994.1 - 0.0044 16.7 0.3 0.0044 16.7 0.2 2.3 1 1 1 2 2 2 1 TMEM154 protein family Hamartin PF04388.7 XP_011276994.1 - 0.026 13.2 16.0 0.027 13.1 11.1 1.1 1 0 0 1 1 1 0 Hamartin protein Mitofilin PF09731.4 XP_011276994.1 - 0.039 12.6 6.0 0.047 12.3 4.2 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein EphA2_TM PF14575.1 XP_011276994.1 - 0.05 14.0 0.1 0.29 11.5 0.0 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF912 PF06024.7 XP_011276994.1 - 0.069 13.1 5.7 7.1 6.7 4.0 2.9 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Hid1 PF12722.2 XP_011276994.1 - 0.91 7.1 18.1 1.3 6.6 12.5 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein ORC6 PF05460.8 XP_011276994.1 - 3 6.8 19.1 4 6.4 13.2 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF2408 PF10303.4 XP_011276995.1 - 1.4e-61 206.4 20.4 3.9e-37 127.3 1.0 5.3 2 2 2 4 4 4 3 Protein of unknown function (DUF2408) DUF479 PF04336.7 XP_011276995.1 - 0.11 12.5 0.7 4 7.5 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function, DUF479 Syntaxin_2 PF14523.1 XP_011276995.1 - 0.15 12.0 9.1 3.7 7.6 0.1 3.6 3 0 0 3 3 3 0 Syntaxin-like protein LemA PF04011.7 XP_011276995.1 - 0.51 9.4 4.8 1.2 8.1 0.1 2.7 2 1 1 3 3 3 0 LemA family DUF2457 PF10446.4 XP_011276995.1 - 3.1 6.4 16.2 6.2 5.4 11.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Seryl_tRNA_N PF02403.17 XP_011276995.1 - 4.6 7.3 12.8 0.044 13.8 1.0 3.2 4 0 0 4 4 4 0 Seryl-tRNA synthetase N-terminal domain Asn_synthase PF00733.16 XP_011276996.1 - 1e-69 234.8 0.0 1.4e-69 234.4 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 XP_011276996.1 - 5.2e-33 113.4 0.0 9.2e-33 112.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 XP_011276996.1 - 1.5e-27 96.1 0.0 6.2e-27 94.1 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.3 XP_011276996.1 - 3.8e-08 32.8 0.0 6.8e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein GATase_2 PF00310.16 XP_011276996.1 - 0.00076 18.2 0.0 0.32 9.6 0.0 2.9 1 1 2 3 3 3 2 Glutamine amidotransferases class-II NAD_synthase PF02540.12 XP_011276996.1 - 0.074 11.9 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 NAD synthase Pkinase PF00069.20 XP_011276997.1 - 2.7e-05 23.4 1.9 8.9e-05 21.7 1.3 1.9 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 XP_011276997.1 - 0.0043 16.8 0.0 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family CDP-OH_P_transf PF01066.16 XP_011276998.1 - 2e-11 44.0 3.1 3.6e-11 43.2 2.1 1.4 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Dishevelled PF02377.10 XP_011276998.1 - 1 9.5 4.8 0.52 10.5 1.7 1.7 2 0 0 2 2 2 0 Dishevelled specific domain GP41 PF00517.12 XP_011276999.1 - 0.098 12.2 5.5 0.023 14.2 1.2 2.0 1 1 1 2 2 2 0 Retroviral envelope protein DUF912 PF06024.7 XP_011276999.1 - 0.82 9.7 5.7 0.33 11.0 0.7 2.6 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) PH PF00169.24 XP_011277000.1 - 7.8e-12 45.3 1.5 7.8e-12 45.3 1.1 2.5 2 0 0 2 2 2 1 PH domain 6PF2K PF01591.13 XP_011277001.1 - 4.2e-53 179.7 7.3 6.5e-53 179.0 5.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase AAA_33 PF13671.1 XP_011277001.1 - 0.0051 16.6 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 XP_011277001.1 - 0.02 15.6 0.1 0.18 12.6 0.0 2.7 1 1 0 2 2 2 0 AAA domain DASH_Dam1 PF08653.5 XP_011277002.1 - 9.4e-20 70.1 2.4 1e-19 70.0 0.8 1.7 2 0 0 2 2 2 1 DASH complex subunit Dam1 Borrelia_REV PF03978.8 XP_011277002.1 - 0.013 15.2 0.3 0.018 14.7 0.2 1.3 1 0 0 1 1 1 0 Borrelia burgdorferi REV protein DUF3439 PF11921.3 XP_011277002.1 - 0.066 12.9 5.8 0.11 12.1 4.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) LRR_6 PF13516.1 XP_011277003.1 - 0.46 10.7 4.8 3.8 7.8 0.0 5.0 5 1 0 5 5 5 0 Leucine Rich repeat DUF4351 PF14261.1 XP_011277003.1 - 0.89 9.4 6.0 17 5.3 0.2 4.3 4 1 1 5 5 5 0 Domain of unknown function (DUF4351) LRR_4 PF12799.2 XP_011277004.1 - 8.6 6.1 36.1 3.2 7.4 0.9 8.3 5 3 3 8 8 8 0 Leucine Rich repeats (2 copies) LRR_4 PF12799.2 XP_011277006.1 - 0.042 13.4 45.1 1.2 8.7 5.3 8.4 3 2 3 6 6 6 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 XP_011277006.1 - 0.08 12.7 32.3 2.4 7.9 3.8 6.8 4 3 1 5 5 5 0 Leucine rich repeat LRR_4 PF12799.2 XP_011277007.1 - 6.8e-05 22.3 41.1 0.033 13.8 6.2 6.9 3 2 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 XP_011277007.1 - 0.00077 19.1 31.8 0.61 9.8 4.4 7.1 4 2 0 6 6 6 4 Leucine rich repeat LRR_7 PF13504.1 XP_011277007.1 - 0.58 10.5 15.1 37 5.1 0.1 7.6 7 1 0 7 7 7 0 Leucine rich repeat LRR_4 PF12799.2 XP_011277008.1 - 3.5 7.3 45.9 0.048 13.3 4.4 7.6 5 2 1 6 6 6 0 Leucine Rich repeats (2 copies) PIR PF00399.14 XP_011277009.1 - 3e-24 83.4 49.8 2.3e-07 29.8 1.2 5.0 4 0 0 4 4 4 4 Yeast PIR protein repeat TPP_enzyme_C PF02775.16 XP_011277009.1 - 0.012 15.1 0.1 0.05 13.1 0.0 1.9 1 1 1 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF2710 PF10921.3 XP_011277009.1 - 0.18 11.9 1.3 0.33 11.1 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2710) TFIIA PF03153.8 XP_011277009.1 - 0.55 10.0 11.3 0.69 9.7 7.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Adeno_hexon PF01065.14 XP_011277009.1 - 1.6 7.4 4.7 2 7.1 3.3 1.1 1 0 0 1 1 1 0 Hexon, adenovirus major coat protein, N-terminal domain PAP1 PF08601.5 XP_011277009.1 - 3.5 7.2 19.1 4.5 6.8 13.3 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Macoilin PF09726.4 XP_011277009.1 - 3.8 5.6 19.1 4.5 5.4 13.2 1.0 1 0 0 1 1 1 0 Transmembrane protein SOG2 PF10428.4 XP_011277009.1 - 3.8 6.0 19.1 5.3 5.5 13.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein PIR PF00399.14 XP_011277010.1 - 6.2e-37 123.7 86.5 3.2e-06 26.2 6.1 6.7 6 0 0 6 6 6 6 Yeast PIR protein repeat Smoothelin PF12510.3 XP_011277010.1 - 0.78 9.6 6.0 1.1e+02 2.7 0.0 4.7 3 1 2 5 5 5 0 Smoothelin cytoskeleton protein Macoilin PF09726.4 XP_011277010.1 - 1.2 7.3 21.2 1.7 6.8 14.7 1.2 1 0 0 1 1 1 0 Transmembrane protein TFIIA PF03153.8 XP_011277010.1 - 1.4 8.7 18.6 1.8 8.4 12.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BAR_2 PF10455.4 XP_011277010.1 - 3.9 6.3 9.6 64 2.3 5.6 2.9 1 1 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking Acyltransferase PF01553.16 XP_011277011.1 - 6.6e-07 28.8 0.0 3.8e-06 26.3 0.0 2.1 1 1 0 1 1 1 1 Acyltransferase BRF1 PF07741.8 XP_011277011.1 - 0.14 12.3 3.7 0.22 11.7 1.7 2.0 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Pyr_redox_2 PF07992.9 XP_011277012.1 - 2.3e-13 50.4 0.0 4.6e-13 49.5 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 XP_011277012.1 - 3.5e-11 43.3 0.0 7.6e-07 29.4 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 XP_011277012.1 - 0.00013 21.0 0.0 0.044 12.6 0.0 2.9 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.17 XP_011277012.1 - 0.0021 16.9 0.4 1 8.1 0.0 2.7 3 0 0 3 3 3 2 Glucose inhibited division protein A NAD_binding_8 PF13450.1 XP_011277012.1 - 0.0033 17.4 0.0 0.0077 16.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 XP_011277012.1 - 0.068 12.9 0.0 5.2 6.8 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 XP_011277013.1 - 3e-13 49.9 0.0 2.9e-09 37.1 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 XP_011277013.1 - 1.4e-11 44.6 0.0 3.4e-11 43.3 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 XP_011277013.1 - 0.034 13.0 0.0 0.089 11.6 0.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 XP_011277014.1 - 1.3e-18 67.6 0.0 2.9e-17 63.2 0.0 2.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 XP_011277014.1 - 7.1e-11 42.3 0.1 2.1e-06 28.0 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 XP_011277014.1 - 2.3e-05 24.2 0.0 0.24 11.1 0.0 3.4 3 0 0 3 3 3 2 FAD-NAD(P)-binding HI0933_like PF03486.9 XP_011277014.1 - 0.00011 20.8 0.1 0.45 8.9 0.0 3.0 2 1 1 3 3 3 3 HI0933-like protein NAD_binding_8 PF13450.1 XP_011277014.1 - 0.0021 18.0 0.0 0.0049 16.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 XP_011277014.1 - 0.0022 16.9 0.0 0.067 12.0 0.0 2.6 2 1 1 3 3 3 1 Lycopene cyclase protein K_oxygenase PF13434.1 XP_011277014.1 - 0.0026 16.7 0.1 0.054 12.4 0.0 2.5 2 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 XP_011277014.1 - 0.007 15.3 0.0 0.032 13.1 0.0 1.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase GMC_oxred_N PF00732.14 XP_011277014.1 - 0.052 12.6 0.0 0.12 11.4 0.0 1.5 2 0 0 2 2 2 0 GMC oxidoreductase GIDA PF01134.17 XP_011277014.1 - 0.053 12.3 0.0 8 5.1 0.0 2.9 3 0 0 3 3 3 0 Glucose inhibited division protein A PALP PF00291.20 XP_011277015.1 - 1.1e-59 202.1 0.0 1.3e-59 201.9 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBFD_NFYB_HMF PF00808.18 XP_011277016.1 - 3.4e-10 39.8 0.3 3.4e-10 39.8 0.2 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 XP_011277016.1 - 0.002 18.2 0.1 0.0033 17.5 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 MRP-L27 PF09809.4 XP_011277017.1 - 1.1e-30 105.5 0.6 1.9e-30 104.7 0.4 1.4 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L27 DSPc PF00782.15 XP_011277018.1 - 7.8e-25 86.9 0.0 5.6e-22 77.7 0.0 3.2 2 1 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 XP_011277018.1 - 2e-07 30.6 0.8 0.00017 21.0 0.0 3.2 3 0 0 3 3 3 2 Protein-tyrosine phosphatase WD40 PF00400.27 XP_011277019.1 - 2.3e-13 49.4 0.1 7.5e-05 22.4 0.0 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat Apc4_WD40 PF12894.2 XP_011277019.1 - 0.00057 19.3 0.0 0.032 13.7 0.0 3.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain DctQ PF04290.7 XP_011277021.1 - 0.0027 17.4 0.9 0.0027 17.4 0.7 2.1 2 0 0 2 2 2 1 Tripartite ATP-independent periplasmic transporters, DctQ component DUF202 PF02656.10 XP_011277021.1 - 0.42 10.8 2.9 1.4 9.1 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF202) PRCC PF10253.4 XP_011277022.1 - 4.7e-15 56.7 4.5 4.7e-15 56.7 3.1 2.0 1 1 1 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting Xpo1 PF08389.7 XP_011277023.1 - 1.9e-32 112.1 3.4 1.9e-32 112.1 2.3 4.3 5 0 0 5 5 5 1 Exportin 1-like protein IBN_N PF03810.14 XP_011277023.1 - 0.0018 18.1 9.2 0.0051 16.6 0.0 5.2 5 0 0 5 5 5 1 Importin-beta N-terminal domain Rep_fac_C PF08542.6 XP_011277025.1 - 7.9e-16 57.8 0.3 2.7e-15 56.0 0.1 2.0 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 XP_011277025.1 - 8.6e-10 38.5 0.4 7.9e-09 35.3 0.0 2.3 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA PF00004.24 XP_011277025.1 - 3.5e-09 36.9 0.0 8e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BTB_2 PF02214.17 XP_011277026.1 - 0.02 15.0 0.0 0.074 13.2 0.0 1.9 2 0 0 2 2 2 0 BTB/POZ domain DBINO PF13892.1 XP_011277026.1 - 0.055 13.5 0.3 0.082 12.9 0.2 1.1 1 0 0 1 1 1 0 DNA-binding domain Yae1_N PF09811.4 XP_011277027.1 - 1.1e-11 44.1 0.2 1.7e-11 43.4 0.2 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal FAT PF02259.18 XP_011277028.1 - 2.7e-138 460.7 1.9 2.7e-138 460.7 1.3 2.3 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.22 XP_011277028.1 - 1.4e-59 201.4 0.1 2.4e-59 200.6 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.3 XP_011277028.1 - 7.4e-54 181.9 1.9 7.4e-54 181.9 1.3 4.7 5 0 0 5 5 5 1 Domain of unknown function (DUF3385) Rapamycin_bind PF08771.6 XP_011277028.1 - 1.4e-41 140.5 0.3 1.4e-41 140.5 0.2 3.4 3 0 0 3 3 3 1 Rapamycin binding domain HEAT_2 PF13646.1 XP_011277028.1 - 4.4e-19 68.5 2.0 0.011 15.9 0.0 9.8 7 2 2 9 9 9 4 HEAT repeats FATC PF02260.15 XP_011277028.1 - 3.6e-18 64.6 2.2 6.8e-18 63.8 0.2 2.5 3 0 0 3 3 3 1 FATC domain HEAT_EZ PF13513.1 XP_011277028.1 - 8.3e-14 51.5 9.4 7.1e-05 23.1 0.0 10.3 10 2 2 12 12 10 3 HEAT-like repeat HEAT PF02985.17 XP_011277028.1 - 8.2e-09 34.8 6.4 0.06 13.4 0.0 9.2 9 0 0 9 9 9 1 HEAT repeat Vac14_Fab1_bd PF12755.2 XP_011277028.1 - 0.0017 18.7 5.7 22 5.5 0.0 6.5 5 2 2 7 7 6 0 Vacuolar 14 Fab1-binding region TAFH PF07531.9 XP_011277028.1 - 0.0049 16.4 0.3 0.034 13.7 0.2 2.6 1 0 0 1 1 1 1 NHR1 homology to TAF UME PF08064.8 XP_011277028.1 - 0.023 14.6 9.6 0.017 15.0 0.5 4.9 6 1 2 8 8 8 0 UME (NUC010) domain Apc3 PF12895.2 XP_011277028.1 - 0.12 12.4 4.9 6.7 6.9 0.0 3.8 4 0 0 4 4 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Actin PF00022.14 XP_011277029.1 - 1.7e-89 300.0 0.0 3.6e-89 298.9 0.0 1.5 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 XP_011277029.1 - 0.00022 19.9 0.0 0.031 12.8 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Agenet PF05641.7 XP_011277029.1 - 0.13 12.4 0.0 0.36 11.0 0.0 1.7 1 0 0 1 1 1 0 Agenet domain Cpn60_TCP1 PF00118.19 XP_011277030.1 - 5.6e-151 503.4 3.3 6.4e-151 503.2 2.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family HEAT_2 PF13646.1 XP_011277031.1 - 2.7e-35 120.4 0.2 1.8e-16 60.2 0.1 3.3 2 1 2 4 4 4 4 HEAT repeats HEAT_PBS PF03130.11 XP_011277031.1 - 2.5e-19 67.6 0.0 5.2e-05 23.3 0.0 6.1 6 0 0 6 6 6 4 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 XP_011277031.1 - 5.1e-11 42.7 2.8 9e-06 26.0 0.2 4.9 2 2 3 5 5 5 4 HEAT-like repeat HEAT PF02985.17 XP_011277031.1 - 4.6e-09 35.5 0.3 0.037 14.0 0.0 5.6 6 0 0 6 6 6 3 HEAT repeat Arm PF00514.18 XP_011277031.1 - 0.1 12.4 0.1 1.3 8.9 0.0 2.7 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat PAC2 PF09754.4 XP_011277032.1 - 3.6e-30 105.4 0.4 2.9e-28 99.2 0.3 2.1 1 1 0 1 1 1 1 PAC2 family DUF106 PF01956.11 XP_011277033.1 - 2.4e-51 173.5 0.4 3e-51 173.2 0.3 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF106 ATP_bind_1 PF03029.12 XP_011277034.1 - 1.4e-72 244.1 0.1 2.3e-72 243.3 0.1 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 XP_011277034.1 - 1.5e-05 24.5 1.9 6.2e-05 22.5 0.3 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SBP_bac_8 PF13416.1 XP_011277034.1 - 0.0035 17.1 0.4 0.0059 16.3 0.3 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein FeoB_N PF02421.13 XP_011277034.1 - 0.012 14.8 0.3 0.048 12.9 0.0 2.1 3 0 0 3 3 3 0 Ferrous iron transport protein B ArgK PF03308.11 XP_011277034.1 - 0.058 12.1 0.2 0.11 11.2 0.1 1.5 1 0 0 1 1 1 0 ArgK protein Lipase_GDSL_3 PF14606.1 XP_011277034.1 - 2.5 7.8 6.0 1.7 8.3 0.0 2.8 3 1 0 3 3 3 0 GDSL-like Lipase/Acylhydrolase family DUF1237 PF06824.6 XP_011277035.1 - 1.9e-177 590.1 0.0 2.2e-177 589.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) F-box-like_2 PF13013.1 XP_011277037.1 - 0.52 10.0 0.0 0.52 10.0 0.0 2.5 4 0 0 4 4 4 0 F-box-like domain PfkB PF00294.19 XP_011277038.1 - 9.7e-15 54.4 0.0 1.4e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 XP_011277038.1 - 0.0017 17.5 0.0 0.0023 17.1 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase DUF4588 PF15251.1 XP_011277040.1 - 3.5e-10 40.2 10.6 9.4e-10 38.8 7.3 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) PEMT PF04191.8 XP_011277041.1 - 4.3e-29 100.7 3.3 5.2e-29 100.4 2.3 1.1 1 0 0 1 1 1 1 Phospholipid methyltransferase ABC_membrane PF00664.18 XP_011277043.1 - 5.6e-87 291.6 35.3 1.1e-43 149.7 10.1 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 XP_011277043.1 - 3.9e-60 202.0 3.5 1.2e-29 103.4 0.0 3.5 3 1 0 3 3 3 2 ABC transporter SMC_N PF02463.14 XP_011277043.1 - 4.7e-16 58.6 8.8 9.6e-08 31.5 0.1 4.6 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 XP_011277043.1 - 6.6e-10 39.2 0.3 0.00074 19.5 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 XP_011277043.1 - 1.6e-09 37.1 1.6 0.0011 18.4 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 XP_011277043.1 - 5.7e-09 36.3 11.4 1.7e-05 24.9 1.3 4.3 3 2 1 4 4 4 2 AAA domain AAA_10 PF12846.2 XP_011277043.1 - 9.2e-08 31.8 3.8 0.58 9.5 0.1 4.4 4 0 0 4 4 4 2 AAA-like domain AAA_22 PF13401.1 XP_011277043.1 - 4.3e-07 30.1 4.9 0.011 15.8 1.0 4.1 2 2 0 2 2 2 2 AAA domain AAA_25 PF13481.1 XP_011277043.1 - 1.6e-06 27.6 0.5 0.12 11.7 0.0 3.4 2 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 XP_011277043.1 - 1.7e-06 27.3 0.1 0.047 12.8 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 XP_011277043.1 - 3.8e-06 27.7 1.5 0.24 12.2 0.0 4.1 4 0 0 4 4 4 2 AAA domain AAA_18 PF13238.1 XP_011277043.1 - 8.2e-06 26.1 0.5 0.12 12.6 0.2 3.7 2 1 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 XP_011277043.1 - 1.9e-05 24.2 0.0 0.0042 16.5 0.0 2.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_5 PF07728.9 XP_011277043.1 - 3.6e-05 23.5 0.1 0.35 10.6 0.0 3.3 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) ABC_ATPase PF09818.4 XP_011277043.1 - 5.7e-05 21.8 2.5 0.0015 17.1 0.1 3.5 4 1 0 4 4 4 1 Predicted ATPase of the ABC class CbiA PF01656.18 XP_011277043.1 - 0.00048 19.5 0.3 0.059 12.7 0.1 3.1 3 0 0 3 3 3 1 CobQ/CobB/MinD/ParA nucleotide binding domain MMR_HSR1 PF01926.18 XP_011277043.1 - 0.0011 18.8 0.1 2.7 7.9 0.0 3.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase MobB PF03205.9 XP_011277043.1 - 0.0032 17.1 0.2 2.3 7.9 0.0 2.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 XP_011277043.1 - 0.0062 16.3 7.2 0.07 12.9 0.2 3.4 3 0 0 3 3 3 1 Domain of unknown function DUF87 PRK PF00485.13 XP_011277043.1 - 0.0088 15.6 0.0 0.69 9.4 0.0 2.8 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.1 XP_011277043.1 - 0.013 15.4 0.3 1.6 8.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 XP_011277043.1 - 0.015 15.4 0.0 7 6.8 0.0 2.9 2 0 0 2 2 2 0 RNA helicase Miro PF08477.8 XP_011277043.1 - 0.024 15.1 0.4 8.6 6.8 0.0 3.4 3 0 0 3 3 3 0 Miro-like protein NACHT PF05729.7 XP_011277043.1 - 0.026 14.1 1.3 15 5.2 0.0 3.4 3 0 0 3 3 3 0 NACHT domain Zeta_toxin PF06414.7 XP_011277043.1 - 0.03 13.4 0.0 0.69 8.9 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin SbcCD_C PF13558.1 XP_011277043.1 - 0.063 13.1 0.5 0.44 10.5 0.0 2.6 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit APS_kinase PF01583.15 XP_011277043.1 - 0.087 12.4 0.8 7.5 6.1 0.0 2.9 3 0 0 3 3 2 0 Adenylylsulphate kinase AAA_13 PF13166.1 XP_011277043.1 - 0.14 10.5 12.8 1.6 7.0 0.0 4.9 6 0 0 6 6 5 0 AAA domain AAA_30 PF13604.1 XP_011277043.1 - 0.16 11.5 0.0 21 4.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain DUF3987 PF13148.1 XP_011277043.1 - 0.75 8.2 5.1 7.3 5.0 0.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF3987) ThiF PF00899.16 XP_011277044.1 - 5.1e-48 162.3 0.1 1.7e-28 99.0 0.1 2.5 2 0 0 2 2 2 2 ThiF family UBA_e1_C PF09358.5 XP_011277044.1 - 9e-47 158.3 0.2 3.6e-46 156.4 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin-activating enzyme e1 C-terminal domain UBACT PF02134.16 XP_011277044.1 - 2.3e-33 113.5 5.5 7.8e-23 79.8 0.2 3.3 3 0 0 3 3 3 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 XP_011277044.1 - 1.4e-23 82.0 0.1 1.4e-19 69.1 0.0 2.6 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site Mog1 PF04603.7 XP_011277045.1 - 3.4e-19 69.1 0.2 2e-18 66.6 0.2 2.2 1 1 0 1 1 1 1 Ran-interacting Mog1 protein Gly_transf_sug PF04488.10 XP_011277046.1 - 7.8e-13 48.7 0.0 3.6e-12 46.5 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Tmemb_9 PF05434.6 XP_011277046.1 - 0.031 14.0 0.5 0.051 13.3 0.3 1.2 1 0 0 1 1 1 0 TMEM9 TcdA_TcdB PF12919.2 XP_011277046.1 - 0.045 12.2 4.5 0.13 10.6 0.0 2.1 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain Chordopox_A30L PF06015.7 XP_011277046.1 - 0.061 12.9 3.7 0.05 13.2 1.1 2.0 2 0 0 2 2 2 0 Chordopoxvirus A30L protein IncA PF04156.9 XP_011277046.1 - 7.3 6.1 10.1 17 4.9 7.0 1.6 1 1 0 1 1 1 0 IncA protein Cu-oxidase_2 PF07731.9 XP_011277047.1 - 2.9e-40 136.9 2.8 1.9e-31 108.4 0.1 3.4 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 XP_011277047.1 - 1.2e-38 131.4 0.9 1.3e-37 128.1 0.1 2.5 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.17 XP_011277047.1 - 4.4e-33 114.4 0.4 4.4e-33 114.4 0.2 2.3 3 0 0 3 3 3 1 Multicopper oxidase Cupredoxin_1 PF13473.1 XP_011277047.1 - 0.11 12.4 0.0 6.3 6.7 0.0 3.3 3 1 0 3 3 3 0 Cupredoxin-like domain Phosphoesterase PF04185.9 XP_011277048.1 - 7e-39 134.0 7.2 4.2e-38 131.5 3.0 2.5 1 1 1 2 2 2 2 Phosphoesterase family MFS_1 PF07690.11 XP_011277049.1 - 3e-14 52.4 21.4 9e-13 47.6 13.4 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily V_ATPase_I PF01496.14 XP_011277049.1 - 0.0058 14.5 0.0 0.0087 13.9 0.0 1.2 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family PPTA PF01239.17 XP_011277050.1 - 8.7e-42 138.7 13.6 3.2e-10 38.9 0.8 5.5 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat DDE_Tnp_ISL3 PF01610.12 XP_011277050.1 - 0.037 13.6 0.9 0.056 13.0 0.7 1.5 1 0 0 1 1 1 0 Transposase DUF4219 PF13961.1 XP_011277050.1 - 2.3 7.7 6.8 4.5 6.8 0.1 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4219) DnaJ PF00226.26 XP_011277051.1 - 2e-26 91.4 0.7 3.1e-26 90.8 0.5 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 XP_011277051.1 - 2.7e-16 59.3 20.8 4.7e-16 58.6 14.4 1.4 1 0 0 1 1 1 1 DnaJ central domain CTDII PF01556.13 XP_011277051.1 - 2e-12 46.8 0.0 6.2e-11 42.0 0.1 2.7 3 0 0 3 3 3 1 DnaJ C terminal domain HypA PF01155.14 XP_011277051.1 - 0.0024 17.5 5.4 0.17 11.6 0.1 2.2 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family DZR PF12773.2 XP_011277051.1 - 0.14 12.0 11.0 1.2 8.9 0.6 2.3 2 0 0 2 2 2 0 Double zinc ribbon DUF1272 PF06906.6 XP_011277051.1 - 3.7 7.4 11.1 19 5.2 4.0 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF1272) Tubulin_3 PF14881.1 XP_011277052.1 - 5.6e-28 97.6 0.0 1.2e-27 96.5 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 XP_011277052.1 - 2.3e-26 92.1 2.1 1.6e-25 89.3 0.4 2.4 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin PF00091.20 XP_011277052.1 - 0.0071 16.1 0.0 0.033 14.0 0.0 2.0 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Sugar_tr PF00083.19 XP_011277053.1 - 1.2e-76 258.1 26.3 1.4e-76 257.9 18.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 XP_011277053.1 - 2.2e-17 62.8 20.5 2.2e-17 62.8 14.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sigma70_r4 PF04545.11 XP_011277053.1 - 0.12 11.6 0.1 0.23 10.8 0.1 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 Rick_17kDa_Anti PF05433.10 XP_011277053.1 - 0.37 10.4 5.5 0.21 11.2 2.1 1.9 2 0 0 2 2 2 0 Glycine zipper 2TM domain Sugar_tr PF00083.19 XP_011277055.1 - 6.3e-76 255.7 18.0 7.3e-76 255.5 12.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 XP_011277055.1 - 3.3e-16 58.9 16.2 3.3e-16 58.9 11.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 XP_011277056.1 - 1.3e-75 254.7 18.7 1.5e-75 254.5 13.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 XP_011277056.1 - 8.5e-23 80.6 13.7 8.5e-23 80.6 9.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sigma70_r4 PF04545.11 XP_011277056.1 - 0.065 12.5 0.1 0.13 11.5 0.1 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 IPPT PF01715.12 XP_011277057.1 - 1.5e-71 240.4 0.2 2.4e-71 239.7 0.1 1.3 1 0 0 1 1 1 1 IPP transferase AAA_17 PF13207.1 XP_011277057.1 - 0.00025 21.8 0.9 0.0039 18.0 0.0 3.2 2 1 0 3 3 3 1 AAA domain AAA_22 PF13401.1 XP_011277057.1 - 0.0028 17.8 0.1 1.3 9.1 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 XP_011277057.1 - 0.0044 17.3 0.5 0.0044 17.3 0.3 3.3 3 1 0 3 3 3 1 AAA domain ABC_tran PF00005.22 XP_011277057.1 - 0.017 15.4 1.3 0.2 11.9 0.0 2.9 3 0 0 3 3 3 0 ABC transporter AAA_33 PF13671.1 XP_011277057.1 - 0.11 12.3 0.0 0.78 9.6 0.0 2.4 3 0 0 3 3 3 0 AAA domain zf-met PF12874.2 XP_011277057.1 - 3.2 8.1 5.6 0.34 11.1 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 XP_011277057.1 - 9.5 6.5 9.5 0.22 11.7 0.9 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding BRO1 PF03097.13 XP_011277058.1 - 1.9e-100 336.3 2.0 1.9e-100 336.3 1.4 2.7 3 0 0 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 XP_011277058.1 - 5.9e-63 212.5 16.0 5.9e-63 212.5 11.1 4.8 5 1 0 5 5 5 2 ALIX V-shaped domain binding to HIV Myb_DNA-binding PF00249.26 XP_011277058.1 - 2.4e-19 69.1 0.5 3.8e-09 36.4 0.0 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 XP_011277058.1 - 4.8e-18 65.0 2.9 5.8e-12 45.5 0.6 3.7 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_Cef PF11831.3 XP_011277058.1 - 5.6e-15 55.1 21.9 5.6e-15 55.1 15.2 2.2 2 0 0 2 2 2 1 pre-mRNA splicing factor component RRP7 PF12923.2 XP_011277060.1 - 0.0077 16.2 5.0 0.012 15.6 0.5 2.3 1 1 1 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) APC_CDC26 PF10471.4 XP_011277060.1 - 0.17 12.6 0.0 0.17 12.6 0.0 2.5 2 1 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 DUF2962 PF11176.3 XP_011277061.1 - 2e-53 180.1 8.3 2.3e-53 179.9 5.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) FLILHELTA PF10306.4 XP_011277063.1 - 8e-23 80.2 0.1 1.1e-22 79.7 0.1 1.2 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA Pkinase PF00069.20 XP_011277064.1 - 0.00059 19.0 1.3 0.00097 18.3 0.4 1.7 2 0 0 2 2 2 1 Protein kinase domain EcKinase PF02958.15 XP_011277064.1 - 0.0072 15.5 0.8 0.014 14.5 0.6 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase Kdo PF06293.9 XP_011277064.1 - 0.014 14.4 0.1 0.027 13.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 XP_011277064.1 - 0.037 13.7 0.1 0.066 12.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family CheX PF13690.1 XP_011277064.1 - 0.11 12.3 0.1 0.23 11.3 0.1 1.5 1 0 0 1 1 1 0 Chemotaxis phosphatase CheX tRNA-synt_1 PF00133.17 XP_011277065.1 - 2.9e-162 540.7 2.2 5.3e-162 539.9 1.6 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 XP_011277065.1 - 1.1e-24 86.9 0.4 2.2e-24 85.9 0.3 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 XP_011277065.1 - 2e-21 76.1 8.1 7.9e-12 44.5 1.0 4.2 4 1 0 4 4 4 3 tRNA synthetases class I (M) zf-FPG_IleRS PF06827.9 XP_011277065.1 - 4.1e-05 23.1 2.6 7.9e-05 22.1 1.8 1.5 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS tRNA-synt_1_2 PF13603.1 XP_011277065.1 - 0.0014 17.9 0.0 0.0035 16.6 0.0 1.6 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 NAC PF01849.13 XP_011277066.1 - 5.2e-16 57.9 0.0 1.1e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 NAC domain DUF236 PF03057.9 XP_011277066.1 - 0.15 12.0 1.8 0.22 11.4 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function Pyridoxal_deC PF00282.14 XP_011277067.1 - 1.8e-57 194.5 0.0 2.6e-57 193.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 XP_011277067.1 - 4.2e-06 25.7 0.0 7.4e-06 24.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V zf-C2H2 PF00096.21 XP_011277068.1 - 5.1e-10 39.0 10.3 2.4e-05 24.4 1.4 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 XP_011277068.1 - 1.9e-09 37.2 4.8 0.00054 20.1 0.9 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 XP_011277068.1 - 1.5e-05 24.7 1.5 0.0052 16.6 0.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 XP_011277068.1 - 5.6e-05 23.2 6.8 0.001 19.2 0.2 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 XP_011277068.1 - 0.12 12.5 0.5 22 5.3 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF4372 PF14294.1 XP_011277069.1 - 0.1 12.4 0.2 0.17 11.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4372) GATA PF00320.22 XP_011277070.1 - 3.2e-16 58.3 3.0 6.9e-16 57.3 2.1 1.5 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.7 XP_011277070.1 - 0.0094 15.2 0.5 0.019 14.2 0.3 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding DNA_binding_2 PF13724.1 XP_011277070.1 - 4 7.6 6.3 1.4 9.0 1.0 2.9 2 1 0 2 2 2 0 DNA-binding domain ApbA_C PF08546.6 XP_011277071.1 - 2.4e-07 30.7 0.0 4.2e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 XP_011277071.1 - 0.0059 16.0 1.1 0.012 15.0 0.0 2.0 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Herpes_Helicase PF02689.9 XP_011277072.1 - 1.8e-05 22.7 0.0 1.9e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.1 XP_011277072.1 - 0.0005 20.1 0.0 0.00062 19.8 0.0 1.2 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain PIF1 PF05970.9 XP_011277073.1 - 5.4e-21 74.9 0.0 6.5e-21 74.6 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase GMP_synt_C PF00958.17 XP_011277074.1 - 1.3e-40 136.9 0.1 2.9e-40 135.8 0.1 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.23 XP_011277074.1 - 6.7e-40 136.5 0.0 1.1e-39 135.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.12 XP_011277074.1 - 2.1e-09 36.6 0.1 8.7e-06 24.7 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 XP_011277074.1 - 3.1e-07 30.0 0.0 1.9e-06 27.4 0.0 2.3 1 1 0 1 1 1 1 Peptidase C26 QueC PF06508.8 XP_011277074.1 - 0.0025 17.1 0.0 0.062 12.5 0.0 2.1 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 XP_011277074.1 - 0.0047 15.5 0.1 0.0092 14.5 0.0 1.5 1 0 0 1 1 1 1 tRNA methyl transferase ThiI PF02568.9 XP_011277074.1 - 0.0074 15.7 0.0 0.017 14.5 0.0 1.6 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) PAPS_reduct PF01507.14 XP_011277074.1 - 0.011 15.5 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Arginosuc_synth PF00764.14 XP_011277074.1 - 0.014 14.4 0.1 0.022 13.7 0.1 1.2 1 0 0 1 1 1 0 Arginosuccinate synthase Asn_synthase PF00733.16 XP_011277074.1 - 0.038 13.4 0.0 0.07 12.6 0.0 1.4 1 0 0 1 1 1 0 Asparagine synthase DUF2501 PF10696.4 XP_011277074.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2501) ATP_bind_3 PF01171.15 XP_011277074.1 - 0.14 11.6 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 PP-loop family ACPS PF01648.15 XP_011277075.1 - 1.9e-08 34.1 0.1 4.5e-05 23.2 0.0 2.1 2 0 0 2 2 2 2 4'-phosphopantetheinyl transferase superfamily IMS_C PF11799.3 XP_011277075.1 - 0.087 12.7 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 impB/mucB/samB family C-terminal domain Mtc PF03820.12 XP_011277076.1 - 1.8e-119 398.0 0.3 2e-119 397.8 0.2 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier Polysacc_synt_C PF14667.1 XP_011277076.1 - 2.1 8.1 9.6 0.072 12.8 2.5 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain GHMP_kinases_N PF00288.21 XP_011277077.1 - 2.3e-21 75.6 0.2 6.1e-21 74.2 0.1 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 XP_011277077.1 - 2.7e-06 27.4 0.1 2.2e-05 24.5 0.0 2.3 2 0 0 2 2 2 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.4 XP_011277077.1 - 0.00049 19.3 0.0 0.0011 18.1 0.0 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature WD40 PF00400.27 XP_011277078.1 - 4e-42 140.6 8.6 6.9e-10 38.4 0.1 6.6 7 0 0 7 7 7 6 WD domain, G-beta repeat NLE PF08154.7 XP_011277078.1 - 2.1e-26 91.7 0.6 3.6e-26 90.9 0.4 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.3 XP_011277078.1 - 1.3e-07 30.1 1.5 0.0031 15.7 0.2 2.8 2 1 1 3 3 3 2 Nucleoporin Nup120/160 N2227 PF07942.7 XP_011277079.1 - 2.9e-64 216.6 0.0 5e-64 215.8 0.0 1.3 1 0 0 1 1 1 1 N2227-like protein Pkinase PF00069.20 XP_011277080.1 - 0.0077 15.4 0.1 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Zn_clus PF00172.13 XP_011277081.1 - 0.01 15.7 0.8 0.025 14.4 0.5 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Prp19_bind PF06991.6 XP_011277081.1 - 0.012 14.9 1.6 0.014 14.7 1.1 1.1 1 0 0 1 1 1 0 Splicing factor, Prp19-binding domain DUF2683 PF10884.3 XP_011277081.1 - 0.13 12.2 1.5 0.18 11.7 0.1 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2683) SKI PF01202.17 XP_011277082.1 - 0.00066 19.5 0.3 0.00095 19.0 0.2 1.3 1 1 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.1 XP_011277082.1 - 0.0048 17.1 0.0 0.0054 17.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain PH_4 PF15404.1 XP_011277082.1 - 0.054 13.0 0.1 0.061 12.8 0.0 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain APS_kinase PF01583.15 XP_011277082.1 - 0.12 12.0 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF3467 PF11950.3 XP_011277082.1 - 0.12 12.4 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3467) SUV3_C PF12513.3 XP_011277083.1 - 8.6e-13 47.5 0.6 2.5e-12 46.0 0.3 1.9 2 0 0 2 2 2 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 XP_011277083.1 - 3.9e-12 45.8 0.0 1.1e-11 44.4 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Pkinase PF00069.20 XP_011277084.1 - 1.2e-64 218.0 0.0 1.9e-64 217.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011277084.1 - 2.3e-31 108.8 0.0 4.1e-31 108.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 XP_011277084.1 - 0.0047 15.9 0.0 0.0096 14.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like DegV PF02645.11 XP_011277084.1 - 0.099 11.7 3.0 0.23 10.5 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein, DegV family COG1307 APH PF01636.18 XP_011277084.1 - 0.13 12.0 0.0 0.36 10.5 0.0 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF4407 PF14362.1 XP_011277084.1 - 9.1 5.1 7.3 14 4.5 5.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Bromodomain PF00439.20 XP_011277085.1 - 3.3e-19 68.5 0.4 3.3e-19 68.5 0.3 2.9 2 0 0 2 2 2 1 Bromodomain Bromo_TP PF07524.8 XP_011277085.1 - 3.1e-06 26.8 0.0 9.1e-06 25.3 0.0 1.9 1 0 0 1 1 1 1 Bromodomain associated Thiolase_N PF00108.18 XP_011277086.1 - 3e-97 324.7 1.7 5.3e-97 323.9 1.2 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 XP_011277086.1 - 8.1e-46 154.4 2.4 9.5e-46 154.2 0.3 2.2 3 1 0 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 XP_011277086.1 - 1.6e-06 27.8 2.7 2.4e-06 27.2 1.2 1.8 1 1 1 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Pkinase PF00069.20 XP_011277087.1 - 2.7e-49 167.6 0.9 8.3e-48 162.7 0.6 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011277087.1 - 4.8e-25 88.0 0.3 7.3e-19 67.8 0.0 3.1 1 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 XP_011277087.1 - 4.7e-06 25.7 0.0 0.011 14.6 0.0 2.6 3 0 0 3 3 3 2 Kinase-like DUF3942 PF13078.1 XP_011277087.1 - 0.027 14.5 1.5 0.053 13.6 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3942) Sybindin PF04099.7 XP_011277088.1 - 1.2e-40 138.4 4.4 1.2e-15 57.5 0.2 3.1 2 1 1 3 3 3 3 Sybindin-like family Sedlin_N PF04628.8 XP_011277088.1 - 4.7e-10 39.4 0.3 6.4e-10 39.0 0.2 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Prion PF00377.13 XP_011277089.1 - 0.061 13.0 0.2 0.09 12.4 0.1 1.2 1 0 0 1 1 1 0 Prion/Doppel alpha-helical domain Tn916-Xis PF09035.5 XP_011277090.1 - 0.085 12.9 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Excisionase from transposon Tn916 MTHFR PF02219.12 XP_011277091.1 - 1.5e-100 336.0 0.0 2e-100 335.5 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase ERCC4 PF02732.10 XP_011277092.1 - 3.6e-25 88.3 0.0 9.4e-24 83.7 0.0 3.2 3 0 0 3 3 3 1 ERCC4 domain ARID PF01388.16 XP_011277093.1 - 7e-21 73.8 0.0 7e-21 73.8 0.0 4.3 4 1 2 6 6 6 1 ARID/BRIGHT DNA binding domain DUF2893 PF11459.3 XP_011277093.1 - 0.34 10.7 1.2 0.63 9.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknwon function (DUF2893) Tropomyosin_1 PF12718.2 XP_011277094.1 - 2.6e-44 150.5 48.6 3.2e-44 150.2 33.7 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 XP_011277094.1 - 6.9e-07 28.6 44.4 0.0013 17.8 16.7 2.2 1 1 1 2 2 2 2 Tropomyosin CENP-F_leu_zip PF10473.4 XP_011277094.1 - 3.2e-06 27.0 46.1 0.00025 20.8 9.1 2.5 1 1 2 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myosin_tail_1 PF01576.14 XP_011277094.1 - 0.00013 19.8 42.9 0.00016 19.6 29.7 1.0 1 0 0 1 1 1 1 Myosin tail Laminin_II PF06009.7 XP_011277094.1 - 0.00019 21.1 26.9 0.038 13.7 7.5 2.0 1 1 1 2 2 2 2 Laminin Domain II GAS PF13851.1 XP_011277094.1 - 0.00055 19.1 43.5 0.00074 18.7 30.2 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding IncA PF04156.9 XP_011277094.1 - 0.0016 18.0 42.2 0.04 13.5 29.2 2.0 1 1 0 1 1 1 1 IncA protein APG6 PF04111.7 XP_011277094.1 - 0.0024 16.9 46.7 0.19 10.7 14.7 2.0 1 1 1 2 2 2 2 Autophagy protein Apg6 Filament PF00038.16 XP_011277094.1 - 0.0036 16.8 35.7 0.011 15.2 12.4 2.0 1 1 1 2 2 2 1 Intermediate filament protein TMF_DNA_bd PF12329.3 XP_011277094.1 - 0.0048 16.6 53.5 0.033 13.9 14.0 3.2 1 1 2 3 3 3 2 TATA element modulatory factor 1 DNA binding bZIP_1 PF00170.16 XP_011277094.1 - 0.0065 16.3 5.9 0.0065 16.3 4.1 4.9 1 1 2 3 3 3 1 bZIP transcription factor ATG16 PF08614.6 XP_011277094.1 - 0.0073 16.1 41.6 0.27 11.0 10.3 2.0 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) Reo_sigmaC PF04582.7 XP_011277094.1 - 0.01 15.0 9.8 0.27 10.3 1.9 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Prefoldin PF02996.12 XP_011277094.1 - 0.011 15.4 3.7 0.011 15.4 2.5 4.1 1 1 3 4 4 4 0 Prefoldin subunit DUF4201 PF13870.1 XP_011277094.1 - 0.011 15.2 39.4 0.19 11.1 1.4 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) ADIP PF11559.3 XP_011277094.1 - 0.025 14.4 42.3 2.1 8.2 4.4 3.2 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding NPV_P10 PF05531.7 XP_011277094.1 - 0.03 14.5 17.0 0.093 12.9 0.2 3.2 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Mod_r PF07200.8 XP_011277094.1 - 0.053 13.4 36.9 0.7 9.8 10.0 2.8 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein BLOC1_2 PF10046.4 XP_011277094.1 - 0.057 13.5 35.0 0.19 11.9 2.5 3.2 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4200 PF13863.1 XP_011277094.1 - 0.061 13.2 44.2 0.056 13.3 16.1 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) WXG100 PF06013.7 XP_011277094.1 - 0.07 13.1 17.7 2.8 8.0 4.4 4.1 2 2 1 3 3 3 0 Proteins of 100 residues with WXG AAA_27 PF13514.1 XP_011277094.1 - 0.078 10.6 30.8 0.73 7.4 14.8 2.0 1 1 1 2 2 2 0 AAA domain DUF4407 PF14362.1 XP_011277094.1 - 0.086 11.7 23.0 0.14 11.1 15.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3450 PF11932.3 XP_011277094.1 - 0.12 11.6 30.3 0.67 9.1 10.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF3584 PF12128.3 XP_011277094.1 - 0.13 9.6 36.4 0.14 9.4 25.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DASH_Hsk3 PF08227.6 XP_011277094.1 - 0.13 12.4 12.3 0.93 9.7 0.6 3.4 3 1 1 4 4 2 0 DASH complex subunit Hsk3 like FlaC_arch PF05377.6 XP_011277094.1 - 0.15 12.0 28.9 0.49 10.3 0.5 4.8 1 1 4 6 6 6 0 Flagella accessory protein C (FlaC) Nup54 PF13874.1 XP_011277094.1 - 0.17 11.5 27.2 0.64 9.6 7.8 2.1 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 DUF1664 PF07889.7 XP_011277094.1 - 0.21 11.4 20.9 3.1 7.6 8.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ERM PF00769.14 XP_011277094.1 - 0.24 10.8 46.3 0.029 13.9 23.1 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family bZIP_2 PF07716.10 XP_011277094.1 - 0.28 11.0 38.1 1.2 9.0 3.7 4.8 3 1 1 4 4 4 0 Basic region leucine zipper FliD_C PF07195.7 XP_011277094.1 - 0.28 10.4 25.5 0.7 9.1 1.2 3.0 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus AAA_13 PF13166.1 XP_011277094.1 - 0.33 9.3 35.1 0.54 8.6 24.3 1.4 1 1 0 1 1 1 0 AAA domain Fib_alpha PF08702.5 XP_011277094.1 - 0.39 10.8 26.2 0.51 10.4 5.7 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Prefoldin_2 PF01920.15 XP_011277094.1 - 0.39 10.4 48.1 0.17 11.6 4.4 4.0 1 1 3 4 4 4 0 Prefoldin subunit GOLGA2L5 PF15070.1 XP_011277094.1 - 0.4 9.0 29.3 0.61 8.5 20.3 1.3 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 KLRAQ PF10205.4 XP_011277094.1 - 0.48 10.4 30.2 0.7 9.9 7.7 2.2 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein Atg14 PF10186.4 XP_011277094.1 - 0.62 8.9 34.2 1.7 7.4 10.1 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF904 PF06005.7 XP_011277094.1 - 0.64 10.3 51.7 0.12 12.6 3.9 4.1 1 1 2 3 3 2 0 Protein of unknown function (DUF904) DUF972 PF06156.8 XP_011277094.1 - 0.67 10.3 35.7 2.2 8.6 2.5 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF972) EzrA PF06160.7 XP_011277094.1 - 0.75 7.9 34.4 0.068 11.3 6.4 2.2 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA TBPIP PF07106.8 XP_011277094.1 - 0.77 9.2 40.0 3 7.3 10.5 2.3 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Taxilin PF09728.4 XP_011277094.1 - 0.84 8.6 40.3 0.07 12.2 8.6 2.4 1 1 0 1 1 1 0 Myosin-like coiled-coil protein DUF724 PF05266.9 XP_011277094.1 - 0.92 9.0 37.2 1.5 8.3 13.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) OmpH PF03938.9 XP_011277094.1 - 1 9.2 39.9 2 8.3 14.4 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Striatin PF08232.7 XP_011277094.1 - 1.1 9.6 33.8 2.1 8.6 16.4 2.2 1 1 1 2 2 2 0 Striatin family Laminin_I PF06008.9 XP_011277094.1 - 1.1 8.5 34.4 0.36 10.1 9.3 2.4 1 1 1 2 2 2 0 Laminin Domain I Phage_GP20 PF06810.6 XP_011277094.1 - 1.1 8.7 42.5 0.49 9.8 11.7 2.7 1 1 1 2 2 2 0 Phage minor structural protein GP20 TPR_MLP1_2 PF07926.7 XP_011277094.1 - 1.1 9.0 46.9 0.092 12.4 16.6 2.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.6 XP_011277094.1 - 1.2 7.7 38.7 1.5 7.3 17.6 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein CAGE1 PF15066.1 XP_011277094.1 - 1.3 7.4 29.1 2.6 6.3 20.1 1.5 1 1 0 1 1 1 0 Cancer-associated gene protein 1 family DUF3552 PF12072.3 XP_011277094.1 - 1.6 7.9 45.6 0.75 8.9 16.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) DUF641 PF04859.7 XP_011277094.1 - 1.7 8.4 27.8 2.9 7.6 5.0 2.4 1 1 0 2 2 2 0 Plant protein of unknown function (DUF641) Nsp1_C PF05064.8 XP_011277094.1 - 1.7 8.3 26.8 0.32 10.6 6.0 2.4 1 1 1 2 2 2 0 Nsp1-like C-terminal region Ax_dynein_light PF10211.4 XP_011277094.1 - 1.7 8.4 41.8 1.7 8.4 6.5 3.1 1 1 2 3 3 3 0 Axonemal dynein light chain DivIC PF04977.10 XP_011277094.1 - 1.9 8.0 43.6 4.2 6.9 4.5 4.3 1 1 3 4 4 4 0 Septum formation initiator Lectin_N PF03954.9 XP_011277094.1 - 1.9 7.8 19.6 0.45 9.8 3.2 2.8 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain CCDC155 PF14662.1 XP_011277094.1 - 2.3 7.7 43.4 2.2 7.8 11.7 2.4 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 Mnd1 PF03962.10 XP_011277094.1 - 2.3 7.8 40.2 12 5.5 14.4 2.2 1 1 1 2 2 2 0 Mnd1 family TelA PF05816.6 XP_011277094.1 - 2.6 6.6 27.1 0.41 9.2 6.8 2.6 1 1 1 2 2 2 0 Toxic anion resistance protein (TelA) HOOK PF05622.7 XP_011277094.1 - 2.8 5.6 35.5 3.2 5.4 24.6 1.1 1 0 0 1 1 1 0 HOOK protein Fmp27_WPPW PF10359.4 XP_011277094.1 - 3 6.1 33.2 2.6 6.3 12.9 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Scm3 PF10384.4 XP_011277094.1 - 3.1 7.3 9.3 1.8 8.1 0.1 3.2 3 1 1 4 4 2 0 Centromere protein Scm3 TMPIT PF07851.8 XP_011277094.1 - 4.1 6.3 30.4 1 8.3 10.1 2.0 1 1 1 2 2 2 0 TMPIT-like protein DUF745 PF05335.8 XP_011277094.1 - 4.1 6.8 25.7 3.8 6.9 6.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) FemAB PF02388.11 XP_011277094.1 - 4.5 5.8 31.1 2.5 6.7 9.2 2.1 1 1 1 2 2 2 0 FemAB family Uds1 PF15456.1 XP_011277094.1 - 4.6 7.2 35.1 14 5.6 7.4 3.3 1 1 2 3 3 3 0 Up-regulated During Septation Rootletin PF15035.1 XP_011277094.1 - 4.8 7.1 37.7 8.3 6.3 10.7 2.4 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion IFT57 PF10498.4 XP_011277094.1 - 5 5.7 33.7 2.3 6.8 10.2 2.1 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 BRE1 PF08647.6 XP_011277094.1 - 5.1 7.1 38.7 0.47 10.4 9.7 2.2 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Hist_deacetyl PF00850.14 XP_011277094.1 - 5.2 6.2 7.2 5.9 6.0 5.0 1.2 1 0 0 1 1 1 0 Histone deacetylase domain DUF812 PF05667.6 XP_011277094.1 - 5.4 5.3 35.0 38 2.5 24.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF812) DUF342 PF03961.8 XP_011277094.1 - 5.6 5.2 36.8 3 6.1 11.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Adeno_PIX PF03955.9 XP_011277094.1 - 5.6 7.5 20.5 1.7 9.1 1.9 3.2 1 1 2 3 3 3 0 Adenovirus hexon-associated protein (IX) DUF4337 PF14235.1 XP_011277094.1 - 5.6 6.7 37.3 1.6 8.5 3.1 3.1 1 1 1 2 2 1 0 Domain of unknown function (DUF4337) SlyX PF04102.7 XP_011277094.1 - 5.7 7.3 27.5 2 8.8 3.2 3.9 1 1 2 4 4 4 0 SlyX DUF2959 PF11172.3 XP_011277094.1 - 6.3 6.5 22.0 0.19 11.4 2.2 2.7 1 1 1 2 2 1 0 Protein of unknown function (DUF2959) DUF1917 PF08939.5 XP_011277094.1 - 6.4 6.4 14.9 7.9 6.1 10.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1917) MIS13 PF08202.6 XP_011277094.1 - 7.2 5.5 31.3 56 2.6 21.6 2.0 1 1 0 1 1 1 0 Mis12-Mtw1 protein family Cortex-I_coil PF09304.5 XP_011277094.1 - 7.4 6.6 36.8 40 4.3 8.3 3.3 1 1 2 3 3 3 0 Cortexillin I, coiled coil Med4 PF10018.4 XP_011277094.1 - 9.1 5.6 34.7 2 7.7 8.8 3.0 1 1 2 3 3 3 0 Vitamin-D-receptor interacting Mediator subunit 4 DivIVA PF05103.8 XP_011277094.1 - 9.3 6.3 38.7 1.8 8.6 2.4 3.5 1 1 2 3 3 3 0 DivIVA protein Lebercilin PF15619.1 XP_011277094.1 - 9.3 5.6 46.3 32 3.8 15.0 2.2 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease adh_short PF00106.20 XP_011277096.1 - 1.2e-20 74.1 0.0 1.5e-20 73.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 XP_011277096.1 - 1.3e-15 57.8 0.0 1.8e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 XP_011277096.1 - 3.7e-06 26.5 0.0 9.3e-06 25.2 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 XP_011277096.1 - 2.8e-05 24.1 0.0 5.2e-05 23.3 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 XP_011277096.1 - 0.0041 16.3 0.0 0.11 11.6 0.0 2.5 2 1 0 2 2 2 1 Fungal family of unknown function (DUF1776) NmrA PF05368.8 XP_011277096.1 - 0.0059 15.8 0.1 0.015 14.5 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family Eno-Rase_NADH_b PF12242.3 XP_011277096.1 - 0.0063 16.2 0.3 0.017 14.9 0.1 1.8 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase adh_short PF00106.20 XP_011277097.1 - 6.9e-23 81.3 0.0 9.1e-23 80.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 XP_011277097.1 - 1.8e-17 63.9 0.0 2.4e-17 63.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 XP_011277097.1 - 6e-06 25.8 0.1 1.3e-05 24.7 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 XP_011277097.1 - 0.0003 20.8 0.0 0.00048 20.1 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 XP_011277097.1 - 0.00079 19.1 0.2 0.0015 18.2 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 XP_011277097.1 - 0.0014 17.8 0.0 0.035 13.2 0.0 2.2 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) NmrA PF05368.8 XP_011277097.1 - 0.0031 16.7 0.1 0.0076 15.5 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family KR PF08659.5 XP_011277097.1 - 0.0032 17.1 0.0 0.0061 16.2 0.0 1.5 1 1 0 1 1 1 1 KR domain ADH_zinc_N PF00107.21 XP_011277097.1 - 0.077 12.5 0.0 0.14 11.6 0.0 1.4 1 1 0 1 1 1 0 Zinc-binding dehydrogenase DFP PF04127.10 XP_011277097.1 - 0.083 12.4 0.0 0.42 10.2 0.0 1.9 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein adh_short PF00106.20 XP_011277098.1 - 1.6e-19 70.4 0.0 2e-19 70.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 XP_011277098.1 - 9.8e-14 51.6 0.0 1.3e-13 51.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 XP_011277098.1 - 2.1e-05 24.0 0.0 0.00012 21.6 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 XP_011277098.1 - 0.00016 21.7 0.0 0.00033 20.7 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 XP_011277098.1 - 0.00025 20.3 0.0 0.00068 18.9 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family DUF1776 PF08643.5 XP_011277098.1 - 0.0032 16.6 0.0 0.022 13.9 0.0 2.3 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 XP_011277098.1 - 0.0063 16.2 0.2 0.013 15.2 0.2 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ADH_zinc_N PF00107.21 XP_011277098.1 - 0.093 12.2 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase zf-CCCH PF00642.19 XP_011277099.1 - 1.9e-08 33.7 0.3 1.9e-08 33.7 0.2 2.6 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF2183 PF09949.4 XP_011277100.1 - 2.7e-29 101.0 0.3 8.9e-29 99.3 0.1 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) Mem_trans PF03547.13 XP_011277101.1 - 7.9e-71 238.3 1.9 9.6e-71 238.0 1.3 1.1 1 0 0 1 1 1 1 Membrane transport protein Mito_carr PF00153.22 XP_011277102.1 - 6.7e-67 221.2 4.7 7.5e-23 80.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein EmrE PF13536.1 XP_011277102.1 - 0.31 11.2 2.8 0.23 11.6 0.2 2.1 2 1 0 2 2 2 0 Multidrug resistance efflux transporter Ribosomal_S7e PF01251.13 XP_011277104.1 - 2.8e-83 278.0 1.7 3.3e-83 277.8 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Rib_5-P_isom_A PF06026.9 XP_011277105.1 - 1.3e-55 187.3 0.0 1.6e-55 187.0 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.17 XP_011277105.1 - 0.078 12.6 0.0 3.3 7.3 0.0 2.2 1 1 1 2 2 2 0 DeoR C terminal sensor domain Arf PF00025.16 XP_011277106.1 - 1.6e-61 206.5 0.3 1.8e-61 206.3 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 XP_011277106.1 - 8.3e-13 47.9 0.1 9.5e-13 47.7 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 XP_011277106.1 - 1.3e-12 47.3 0.1 1.5e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 XP_011277106.1 - 1.6e-10 40.5 0.1 1.9e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 XP_011277106.1 - 4.6e-10 38.7 0.7 3.6e-09 35.8 0.1 2.0 1 1 1 2 2 2 1 G-protein alpha subunit Miro PF08477.8 XP_011277106.1 - 4.9e-06 27.0 0.0 7.3e-06 26.4 0.0 1.4 1 1 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 XP_011277106.1 - 5.7e-06 26.2 0.1 7.7e-06 25.8 0.1 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF1659 PF07872.6 XP_011277106.1 - 0.64 9.6 2.6 0.99 9.0 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1659) SH3_1 PF00018.23 XP_011277107.1 - 1.9e-24 84.7 0.7 4.7e-14 51.5 0.0 3.0 3 0 0 3 3 3 2 SH3 domain SH3_9 PF14604.1 XP_011277107.1 - 2.3e-24 84.7 0.2 4.1e-14 51.8 0.1 2.6 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.18 XP_011277107.1 - 8.6e-23 80.3 1.4 2.2e-22 79.0 0.1 2.5 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_2 PF07653.12 XP_011277107.1 - 1.6e-13 49.9 0.0 1.2e-10 40.7 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_3 PF08239.6 XP_011277107.1 - 0.012 15.8 0.5 3.7 7.8 0.1 2.7 2 0 0 2 2 2 0 Bacterial SH3 domain UNC119_bdg PF15435.1 XP_011277107.1 - 0.1 11.9 2.4 0.12 11.6 0.6 1.8 2 0 0 2 2 2 0 UNC119-binding protein C5orf30 homologue DUF3571 PF12095.3 XP_011277107.1 - 0.61 10.3 3.7 5 7.4 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3571) HMGL-like PF00682.14 XP_011277108.1 - 8.2e-75 251.4 0.0 1.3e-74 250.8 0.0 1.3 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 XP_011277108.1 - 1.1e-23 83.5 0.1 2.5e-23 82.3 0.1 1.7 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain SNF2_N PF00176.18 XP_011277109.1 - 1.9e-72 243.6 0.2 4.1e-72 242.5 0.1 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF4208 PF13907.1 XP_011277109.1 - 5.5e-28 97.1 1.8 5.5e-28 97.1 1.2 3.4 4 0 0 4 4 4 1 Domain of unknown function (DUF4208) Chromo PF00385.19 XP_011277109.1 - 1e-16 60.3 9.6 4e-11 42.4 0.8 3.7 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 XP_011277109.1 - 2.3e-15 56.1 0.0 8.8e-15 54.3 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain NgoMIV_restric PF09015.5 XP_011277109.1 - 5.1e-05 22.4 0.0 0.21 10.5 0.1 2.8 3 0 0 3 3 3 2 NgoMIV restriction enzyme Syja_N PF02383.13 XP_011277110.1 - 1.7e-95 319.4 0.3 2.7e-95 318.7 0.2 1.3 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 XP_011277110.1 - 3.4e-23 82.8 0.0 9.5e-23 81.4 0.0 1.7 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family YEATS PF03366.11 XP_011277112.1 - 7.5e-37 124.9 0.4 1.2e-36 124.2 0.3 1.4 1 0 0 1 1 1 1 YEATS family DUF3686 PF12458.3 XP_011277112.1 - 0.056 11.7 0.0 0.076 11.2 0.0 1.2 1 0 0 1 1 1 0 ATPase involved in DNA repair HR1 PF02185.11 XP_011277112.1 - 0.088 12.5 0.9 0.16 11.7 0.6 1.5 1 0 0 1 1 1 0 Hr1 repeat His_Phos_1 PF00300.17 XP_011277113.1 - 3e-22 79.4 0.0 9e-22 77.8 0.0 1.8 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) TFIIIC_sub6 PF10419.4 XP_011277113.1 - 2.1e-13 49.4 0.4 8.7e-13 47.4 0.0 2.2 2 0 0 2 2 2 1 TFIIIC subunit Maf PF02545.9 XP_011277114.1 - 1.5e-39 135.1 0.0 1.9e-39 134.8 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein LRR_4 PF12799.2 XP_011277115.1 - 0.87 9.2 28.6 2 8.1 0.0 9.0 7 3 2 9 9 9 0 Leucine Rich repeats (2 copies) Utp14 PF04615.8 XP_011277116.1 - 0.063 11.4 24.5 0.077 11.1 17.0 1.3 1 0 0 1 1 1 0 Utp14 protein CENP-T PF15511.1 XP_011277116.1 - 6.3 5.9 28.7 9.8 5.3 19.9 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T uDENN PF03456.13 XP_011277117.1 - 0.066 13.1 0.1 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 uDENN domain GP40 PF11025.3 XP_011277117.1 - 0.39 10.2 4.2 0.73 9.3 2.9 1.4 1 0 0 1 1 1 0 Glycoprotein GP40 of Cryptosporidium RRM_1 PF00076.17 XP_011277118.1 - 2.2e-18 65.6 0.3 2.2e-18 65.6 0.2 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 XP_011277118.1 - 5.1e-13 48.8 0.1 1.1e-12 47.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 XP_011277118.1 - 2.7e-11 43.1 0.3 6.1e-11 42.0 0.2 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 XP_011277118.1 - 0.00023 20.8 0.0 0.00058 19.5 0.0 1.7 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF2009 PF09418.5 XP_011277119.1 - 1.1e-210 700.1 1.1 1.4e-210 699.9 0.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) zf-B_box PF00643.19 XP_011277119.1 - 1.8e-05 24.5 5.0 3.1e-05 23.7 3.5 1.4 1 0 0 1 1 1 1 B-box zinc finger CENP-B_dimeris PF09026.5 XP_011277119.1 - 0.013 15.7 0.6 0.013 15.7 0.4 2.1 2 0 0 2 2 2 0 Centromere protein B dimerisation domain HEAT PF02985.17 XP_011277120.1 - 5.7e-11 41.5 0.0 0.02 14.9 0.0 4.8 4 0 0 4 4 4 3 HEAT repeat Pkinase PF00069.20 XP_011277120.1 - 1.3e-06 27.8 0.0 3.1e-06 26.5 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain CLASP_N PF12348.3 XP_011277120.1 - 1.4e-05 24.6 1.5 0.0002 20.7 0.2 2.5 2 1 0 3 3 3 1 CLASP N terminal HEAT_2 PF13646.1 XP_011277120.1 - 0.00013 22.1 0.1 0.0087 16.3 0.0 3.2 2 1 2 4 4 4 1 HEAT repeats Adaptin_N PF01602.15 XP_011277120.1 - 0.012 14.0 0.4 0.012 14.0 0.3 2.0 2 1 0 2 2 2 0 Adaptin N terminal region HEAT_EZ PF13513.1 XP_011277120.1 - 0.015 15.8 0.0 1.5 9.4 0.0 3.3 3 0 0 3 3 3 0 HEAT-like repeat DEAD PF00270.24 XP_011277121.1 - 2.3e-43 147.5 0.0 2.1e-42 144.4 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 XP_011277121.1 - 2.6e-23 81.6 0.1 1.2e-22 79.5 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 XP_011277121.1 - 0.00046 20.0 0.0 0.001 18.9 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit RNA_pol_L_2 PF13656.1 XP_011277122.1 - 6.6e-33 111.9 0.0 8.9e-33 111.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 XP_011277122.1 - 5.7e-14 50.9 0.0 7.3e-14 50.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain zf-C2H2 PF00096.21 XP_011277123.1 - 9.7e-21 72.8 30.1 8.2e-06 25.8 0.2 5.2 5 0 0 5 5 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 XP_011277123.1 - 2.6e-20 71.6 24.8 2.4e-08 33.8 0.4 4.6 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2_4 PF13894.1 XP_011277123.1 - 1.6e-14 53.0 22.4 0.00033 20.7 0.4 4.8 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 XP_011277123.1 - 7.9e-05 22.6 13.5 0.48 10.6 0.0 4.3 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 XP_011277123.1 - 0.00084 19.0 18.1 0.014 15.1 0.6 4.0 3 1 1 4 4 4 2 BED zinc finger zf-met PF12874.2 XP_011277123.1 - 0.0024 18.0 14.0 0.31 11.3 0.0 4.8 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 XP_011277123.1 - 0.031 14.1 0.5 0.031 14.1 0.3 4.8 5 0 0 5 5 5 0 C2H2-type zinc finger zf-Di19 PF05605.7 XP_011277123.1 - 0.04 14.0 6.4 0.098 12.7 0.2 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-CHCC PF10276.4 XP_011277123.1 - 0.056 13.3 9.1 1 9.2 0.7 3.3 3 0 0 3 3 3 0 Zinc-finger domain zf-C2H2_2 PF12756.2 XP_011277123.1 - 1.4 9.0 10.8 3.8 7.6 1.4 3.5 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.1 XP_011277123.1 - 7.6 6.3 11.5 1.7 8.4 0.1 3.3 3 0 0 3 3 3 0 zinc-finger of a C2HC-type MARVEL PF01284.18 XP_011277124.1 - 6.6e-21 74.6 6.6 9.6e-21 74.1 4.6 1.2 1 0 0 1 1 1 1 Membrane-associating domain Fungal_trans PF04082.13 XP_011277125.1 - 3.3e-36 124.5 0.2 1.2e-35 122.6 0.1 1.9 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 XP_011277125.1 - 1.1e-11 44.3 11.6 2.1e-11 43.5 8.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TMEM247 PF15444.1 XP_011277125.1 - 4.4 7.0 7.8 2.5 7.8 3.6 1.8 2 0 0 2 2 2 0 Transmembrane protein 247 Epimerase PF01370.16 XP_011277126.1 - 8.7e-24 84.2 0.0 1.1e-23 83.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 XP_011277126.1 - 1.2e-17 63.5 0.1 1.5e-17 63.2 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 XP_011277126.1 - 1.1e-12 47.7 0.6 2.7e-12 46.4 0.1 1.9 2 1 1 3 3 3 1 NmrA-like family NAD_binding_10 PF13460.1 XP_011277126.1 - 2.2e-12 47.3 0.0 3.6e-12 46.6 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 XP_011277126.1 - 5e-08 32.1 0.0 6.4e-08 31.8 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 XP_011277126.1 - 1.2e-07 30.8 0.0 1.1e-05 24.5 0.0 2.4 1 1 0 1 1 1 1 Male sterility protein Saccharop_dh PF03435.13 XP_011277126.1 - 0.00012 21.2 0.1 0.00018 20.6 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase TrkA_N PF02254.13 XP_011277126.1 - 0.00019 21.3 0.0 0.00039 20.4 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain adh_short PF00106.20 XP_011277126.1 - 0.00069 19.5 0.1 0.0015 18.4 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 XP_011277126.1 - 0.03 13.9 0.0 0.049 13.2 0.0 1.4 1 0 0 1 1 1 0 KR domain DapB_N PF01113.15 XP_011277126.1 - 0.047 13.5 0.1 0.11 12.4 0.1 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_2 PF03446.10 XP_011277126.1 - 0.066 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Polysacc_synt_2 PF02719.10 XP_011277126.1 - 0.12 11.2 0.2 0.23 10.2 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein PLA2_B PF01735.13 XP_011277127.1 - 5e-209 694.5 2.1 6.1e-209 694.2 1.5 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain FTR1 PF03239.9 XP_011277128.1 - 4.3e-74 249.2 4.8 9e-50 169.3 2.4 2.0 1 1 0 2 2 2 2 Iron permease FTR1 family NfeD PF01957.13 XP_011277128.1 - 0.026 14.6 0.1 0.026 14.6 0.0 2.8 3 1 0 3 3 3 0 NfeD-like C-terminal, partner-binding ADH_zinc_N PF00107.21 XP_011277129.1 - 1.2e-12 47.5 0.0 2.2e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 XP_011277129.1 - 0.0023 18.8 0.0 0.0086 16.9 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 XP_011277129.1 - 0.03 14.0 0.0 0.092 12.5 0.0 1.7 1 1 1 2 2 2 0 Alcohol dehydrogenase GroES-like domain Inp1 PF12634.2 XP_011277130.1 - 1.9e-32 111.9 2.8 4.3e-32 110.7 0.2 2.7 2 0 0 2 2 2 1 Inheritance of peroxisomes protein 1 TT_ORF2 PF02957.10 XP_011277130.1 - 0.85 10.3 3.8 0.47 11.1 0.6 2.0 2 0 0 2 2 2 0 TT viral ORF2 Porin_3 PF01459.17 XP_011277131.1 - 1.8e-81 273.4 1.2 2.1e-81 273.2 0.9 1.0 1 0 0 1 1 1 1 Eukaryotic porin Med9 PF07544.8 XP_011277132.1 - 1.4e-08 34.3 6.8 3.5e-08 33.0 0.6 3.4 2 1 1 3 3 3 1 RNA polymerase II transcription mediator complex subunit 9 DUF4201 PF13870.1 XP_011277132.1 - 0.022 14.2 2.0 0.027 13.9 0.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) FlgM PF04316.8 XP_011277132.1 - 0.9 9.5 3.6 2.3 8.2 0.0 2.7 2 1 0 2 2 2 0 Anti-sigma-28 factor, FlgM ERG2_Sigma1R PF04622.7 XP_011277133.1 - 3.8e-88 294.3 0.4 4.2e-88 294.2 0.3 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein ERG2_Sigma1R PF04622.7 XP_011277134.1 - 1.6e-82 275.9 0.1 2e-82 275.6 0.1 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein PCI PF01399.22 XP_011277135.1 - 2.3e-08 34.3 1.5 2.3e-08 34.3 1.0 2.8 2 2 1 3 3 3 1 PCI domain CompInhib_SCIN PF11546.3 XP_011277135.1 - 0.0055 16.5 0.1 0.0055 16.5 0.0 2.5 3 0 0 3 3 3 1 Staphylococcal complement inhibitor SCIN TPR_7 PF13176.1 XP_011277135.1 - 0.013 15.2 0.2 0.057 13.2 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 XP_011277135.1 - 2.9 7.8 4.7 0.86 9.5 0.1 2.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Whi5 PF08528.6 XP_011277136.1 - 1e-06 28.1 0.4 1e-06 28.1 0.3 2.3 2 0 0 2 2 2 1 Whi5 like LCAT PF02450.10 XP_011277137.1 - 3.3e-116 388.4 0.0 5.2e-116 387.8 0.0 1.3 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_5 PF12695.2 XP_011277137.1 - 6.9e-05 22.6 0.0 0.00019 21.2 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Lipase_2 PF01674.13 XP_011277137.1 - 0.013 14.8 0.0 0.027 13.7 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 2) Abhydrolase_6 PF12697.2 XP_011277137.1 - 0.2 11.4 0.0 0.45 10.3 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family Autophagy_N PF03986.8 XP_011277138.1 - 6.3e-48 162.2 5.0 6.3e-48 162.2 3.4 2.2 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 XP_011277138.1 - 1.9e-24 85.5 2.4 2.3e-24 85.3 0.2 2.3 3 0 0 3 3 3 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 XP_011277138.1 - 5e-15 54.2 1.3 9.4e-15 53.4 0.9 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal RRP7 PF12923.2 XP_011277138.1 - 0.12 12.3 5.3 0.082 12.9 1.1 2.2 2 0 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) GCOM2 PF15328.1 XP_011277138.1 - 0.22 11.2 9.7 1.9 8.1 2.7 2.1 2 0 0 2 2 2 0 Putative GRINL1B complex locus protein 2 PBP1_TM PF14812.1 XP_011277138.1 - 2.6 8.4 16.9 2.5 8.4 4.5 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FYDLN_acid PF09538.5 XP_011277138.1 - 7.5 7.1 21.4 10 6.7 7.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) XPA_C PF05181.7 XP_011277141.1 - 7.4e-24 83.0 0.7 7.4e-24 83.0 0.5 1.9 2 0 0 2 2 2 1 XPA protein C-terminus XPA_N PF01286.13 XP_011277141.1 - 1.2e-06 28.0 5.0 1.2e-06 28.0 3.5 2.1 2 0 0 2 2 2 1 XPA protein N-terminal Vma12 PF11712.3 XP_011277141.1 - 0.016 14.8 0.3 0.016 14.8 0.2 2.0 2 1 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Fer4_10 PF13237.1 XP_011277141.1 - 0.078 12.7 1.0 8.2 6.3 0.0 3.0 3 0 0 3 3 3 0 4Fe-4S dicluster domain Metal_resist PF13801.1 XP_011277141.1 - 0.61 10.0 1.9 3.6 7.6 0.0 2.1 2 0 0 2 2 2 0 Heavy-metal resistance DUF1682 PF07946.9 XP_011277141.1 - 6.7 5.4 13.9 0.081 11.7 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) MatE PF01554.13 XP_011277142.1 - 3.1e-55 186.2 36.5 8.8e-32 109.9 5.1 2.6 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.1 XP_011277142.1 - 0.00045 20.0 13.1 0.00045 20.0 9.1 4.0 4 1 1 5 5 5 2 Polysaccharide biosynthesis C-terminal domain Cyclin_N PF00134.18 XP_011277143.1 - 5e-33 113.3 0.0 8.4e-33 112.6 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain BBP1_C PF15272.1 XP_011277144.1 - 9.9e-19 67.6 23.4 9.9e-19 67.6 16.2 4.0 2 1 2 4 4 4 2 Spindle pole body component BBP1, C-terminal DUF1140 PF06600.6 XP_011277144.1 - 0.016 15.3 3.0 0.016 15.3 2.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1140) SAGA-Tad1 PF12767.2 XP_011277145.1 - 1.1e-60 205.4 0.4 1.8e-60 204.7 0.3 1.4 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit TAF4 PF05236.9 XP_011277145.1 - 0.001 18.4 0.0 0.0025 17.1 0.0 1.6 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family DUF948 PF06103.6 XP_011277146.1 - 1.9 8.3 16.4 2.5 8.0 0.0 4.5 2 2 2 4 4 4 0 Bacterial protein of unknown function (DUF948) Fer2 PF00111.22 XP_011277147.1 - 1.5e-13 50.3 0.4 2e-13 49.8 0.3 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain V-SNARE_C PF12352.3 XP_011277148.1 - 2.4e-20 72.3 5.3 2.4e-20 72.3 3.7 2.1 1 1 1 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.10 XP_011277148.1 - 6.4e-09 35.8 1.8 6.4e-09 35.8 1.3 3.5 2 2 2 4 4 4 1 Vesicle transport v-SNARE protein N-terminus Sec20 PF03908.8 XP_011277148.1 - 0.00091 18.8 1.8 0.00091 18.8 1.2 2.0 2 1 0 2 2 2 1 Sec20 YqjK PF13997.1 XP_011277148.1 - 0.054 13.6 0.0 0.054 13.6 0.0 3.0 3 0 0 3 3 3 0 YqjK-like protein RelB_N PF12910.2 XP_011277148.1 - 0.074 12.4 0.1 0.35 10.2 0.0 2.0 2 0 0 2 2 2 0 Antitoxin of toxin-antitoxin stability system N-terminal Fusion_gly PF00523.13 XP_011277148.1 - 0.076 11.0 4.9 0.052 11.6 2.1 1.7 1 1 1 2 2 2 0 Fusion glycoprotein F0 Rabaptin PF03528.10 XP_011277148.1 - 0.12 12.2 5.1 0.046 13.6 0.9 2.0 1 1 1 2 2 2 0 Rabaptin DUF725 PF05267.7 XP_011277148.1 - 0.41 10.5 3.3 0.6 10.0 0.5 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF725) Tup_N PF08581.5 XP_011277148.1 - 0.53 10.5 6.4 0.2 11.9 1.4 2.2 2 0 0 2 2 2 0 Tup N-terminal Synaptobrevin PF00957.16 XP_011277148.1 - 3 7.5 8.6 0.45 10.1 0.4 2.8 2 1 0 2 2 2 0 Synaptobrevin Glyco_hydro_63 PF03200.11 XP_011277149.1 - 8e-09 33.9 5.6 2.2e-06 25.8 0.2 4.5 4 1 0 4 4 4 2 Mannosyl oligosaccharide glucosidase DUF269 PF03270.8 XP_011277149.1 - 0.015 15.3 0.0 0.033 14.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF269 FA_desaturase PF00487.19 XP_011277150.1 - 5.3e-18 65.3 16.8 5.3e-18 65.3 11.6 1.5 2 0 0 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.23 XP_011277150.1 - 6.6e-14 51.4 0.0 1.4e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF308 PF03729.8 XP_011277150.1 - 0.015 15.2 0.5 0.19 11.7 0.4 2.5 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) HRXXH PF13933.1 XP_011277151.1 - 2.6e-105 351.3 1.1 3.1e-105 351.0 0.7 1.0 1 0 0 1 1 1 1 Putative peptidase family Zip PF02535.17 XP_011277152.1 - 2e-42 145.3 20.0 2.7e-42 144.8 13.8 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter HupE_UreJ PF04955.7 XP_011277152.1 - 0.0048 16.2 6.7 0.0048 16.2 4.7 3.1 2 1 1 3 3 3 2 HupE / UreJ protein Glyco_hydro_17 PF00332.13 XP_011277153.1 - 2e-59 201.1 0.3 2.3e-59 200.9 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 FSH1 PF03959.8 XP_011277154.1 - 4.2e-55 186.4 0.0 5e-55 186.2 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 XP_011277154.1 - 8.9e-13 48.2 0.0 1.2e-12 47.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 XP_011277154.1 - 8e-07 28.7 0.0 5.6e-06 25.9 0.0 1.9 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 XP_011277154.1 - 2.8e-06 27.4 0.0 0.049 13.5 0.0 2.3 1 1 1 2 2 2 2 Alpha/beta hydrolase family DLH PF01738.13 XP_011277154.1 - 0.0018 17.6 0.0 0.0027 17.0 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.15 XP_011277154.1 - 0.035 13.6 0.0 0.063 12.8 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold UPF0227 PF05728.7 XP_011277154.1 - 0.087 12.5 0.4 4.3 7.0 0.0 2.3 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0227) Polysacc_deac_1 PF01522.16 XP_011277155.1 - 6.8e-21 74.1 0.0 1.2e-20 73.3 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.4 XP_011277155.1 - 0.022 14.1 0.0 0.038 13.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) DUF2194 PF09960.4 XP_011277155.1 - 0.091 10.7 0.0 0.13 10.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2194) Methyltransf_11 PF08241.7 XP_011277156.1 - 2.1e-10 40.9 0.0 3.4e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 XP_011277156.1 - 5.7e-09 36.3 0.0 9.8e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 XP_011277156.1 - 1.7e-07 31.8 0.0 2.7e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 XP_011277156.1 - 2.8e-07 30.3 0.0 3.9e-07 29.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 XP_011277156.1 - 4.3e-07 29.6 0.0 8.5e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 XP_011277156.1 - 0.001 19.4 0.0 0.0017 18.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 XP_011277156.1 - 0.0047 16.0 0.0 0.0071 15.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.8 XP_011277156.1 - 0.0053 15.9 0.0 0.0079 15.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 XP_011277156.1 - 0.0057 16.0 0.0 0.0095 15.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 XP_011277156.1 - 0.019 15.0 0.0 0.083 12.9 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Peptidase_C14 PF00656.17 XP_011277157.1 - 2.1e-70 237.2 0.0 2.7e-70 236.9 0.0 1.0 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.1 XP_011277157.1 - 0.061 13.1 0.0 0.5 10.2 0.0 2.3 2 0 0 2 2 2 0 Raptor N-terminal CASPase like domain Mnd1 PF03962.10 XP_011277158.1 - 0.24 11.0 56.3 0.073 12.7 5.1 5.2 2 1 3 5 5 5 0 Mnd1 family NUDIX PF00293.23 XP_011277159.1 - 8e-29 99.9 0.0 1.1e-28 99.5 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Radical_SAM PF04055.16 XP_011277160.1 - 1.3e-16 61.2 0.0 2.8e-16 60.1 0.0 1.6 2 0 0 2 2 2 1 Radical SAM superfamily RhoGAP PF00620.22 XP_011277161.1 - 3.6e-39 133.8 1.2 9.5e-39 132.4 0.8 1.7 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.24 XP_011277161.1 - 3.5e-06 27.1 1.0 7.5e-06 26.0 0.0 2.1 2 0 0 2 2 2 1 PH domain PX PF00787.19 XP_011277161.1 - 1.2e-05 25.0 0.1 4.8e-05 23.1 0.0 2.1 2 0 0 2 2 2 1 PX domain Siah-Interact_N PF09032.6 XP_011277161.1 - 0.011 15.7 3.8 0.011 15.7 2.7 2.3 2 0 0 2 2 2 0 Siah interacting protein, N terminal Spc42p PF11544.3 XP_011277161.1 - 0.011 15.6 3.1 0.011 15.6 2.1 3.5 3 0 0 3 3 3 0 Spindle pole body component Spc42p PH_11 PF15413.1 XP_011277161.1 - 0.13 12.5 2.4 0.57 10.4 0.0 2.8 2 1 0 2 2 2 0 Pleckstrin homology domain Kinetocho_Slk19 PF12709.2 XP_011277162.1 - 6e-27 93.5 12.7 6e-27 93.5 8.8 9.3 2 2 4 9 9 9 1 Central kinetochore-associated Reo_sigmaC PF04582.7 XP_011277162.1 - 4.7e-05 22.7 42.7 0.015 14.5 8.4 4.8 1 1 4 5 5 5 5 Reovirus sigma C capsid protein Atg14 PF10186.4 XP_011277162.1 - 0.00044 19.3 14.2 0.00044 19.3 9.8 6.2 1 1 5 6 6 6 4 UV radiation resistance protein and autophagy-related subunit 14 FliJ PF02050.11 XP_011277162.1 - 0.00084 19.3 4.1 0.00084 19.3 2.8 7.7 2 2 7 9 9 9 2 Flagellar FliJ protein IncA PF04156.9 XP_011277162.1 - 0.0053 16.3 12.3 0.0053 16.3 8.5 7.6 2 1 4 6 6 6 3 IncA protein TPD52 PF04201.10 XP_011277162.1 - 0.0064 16.2 5.2 0.0064 16.2 3.6 7.0 3 2 4 7 7 7 3 Tumour protein D52 family Spc7 PF08317.6 XP_011277162.1 - 0.15 10.6 106.6 0.01 14.5 7.9 6.0 2 1 5 7 7 7 0 Spc7 kinetochore protein WEMBL PF05701.6 XP_011277162.1 - 0.62 8.4 92.5 1.6 7.1 7.3 3.8 1 1 2 3 3 3 0 Weak chloroplast movement under blue light YojJ PF10372.4 XP_011277162.1 - 1 9.2 8.1 0.35 10.7 1.0 3.7 3 1 0 3 3 3 0 Bacterial membrane-spanning protein N-terminus TFIIA PF03153.8 XP_011277163.1 - 4.7e-55 188.0 18.8 2e-31 110.2 7.9 2.0 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit BTV_NS2 PF04514.7 XP_011277163.1 - 0.32 9.8 3.7 0.39 9.5 2.6 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 PBP1_TM PF14812.1 XP_011277163.1 - 4.2 7.7 8.5 0.71 10.2 3.1 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Hist_deacetyl PF00850.14 XP_011277164.1 - 5.3e-65 219.7 0.1 7e-65 219.3 0.1 1.1 1 0 0 1 1 1 1 Histone deacetylase domain DAGAT PF03982.8 XP_011277165.1 - 2e-82 276.2 1.2 2.3e-73 246.4 0.0 2.0 2 0 0 2 2 2 2 Diacylglycerol acyltransferase PqiA PF04403.8 XP_011277165.1 - 0.0048 16.4 0.6 0.0088 15.6 0.4 1.3 1 0 0 1 1 1 1 Paraquat-inducible protein A LicD PF04991.8 XP_011277166.1 - 8.3e-31 107.6 4.2 8.3e-31 107.6 2.9 4.2 3 2 1 4 4 4 1 LicD family RNA_pol_Rpb2_6 PF00562.23 XP_011277167.1 - 1.8e-111 372.5 0.0 2.6e-111 372.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 XP_011277167.1 - 7.2e-44 149.1 0.1 1e-43 148.6 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 XP_011277167.1 - 3.7e-31 108.0 0.1 1.9e-30 105.7 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.7 XP_011277167.1 - 3.1e-24 84.6 0.0 9.3e-24 83.1 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_3 PF04565.11 XP_011277167.1 - 8.1e-24 83.1 0.0 2.6e-23 81.5 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.15 XP_011277167.1 - 9.9e-16 57.7 0.0 3.5e-15 56.0 0.0 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 XP_011277167.1 - 0.0054 16.6 0.1 0.015 15.2 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_POL_M_15KD PF02150.11 XP_011277167.1 - 0.11 12.1 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit E1-E2_ATPase PF00122.15 XP_011277168.1 - 8.5e-79 263.8 0.6 2.5e-78 262.2 0.4 1.9 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 XP_011277168.1 - 6.1e-44 149.7 2.5 6.1e-44 149.7 1.7 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 XP_011277168.1 - 4.3e-32 112.2 0.0 9.6e-32 111.1 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 XP_011277168.1 - 1.2e-16 60.3 0.1 3.1e-16 59.1 0.1 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 XP_011277168.1 - 2.5e-16 60.4 0.0 5.7e-16 59.2 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 XP_011277168.1 - 8.4e-14 50.7 0.0 1.8e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 XP_011277168.1 - 3.4e-06 26.8 5.1 0.00044 19.9 0.5 2.8 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase DUF4134 PF13572.1 XP_011277168.1 - 0.0068 16.5 0.3 0.03 14.4 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4134) Hydrolase_6 PF13344.1 XP_011277168.1 - 0.081 12.8 0.0 0.29 11.0 0.0 1.9 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Pox_A14 PF05767.7 XP_011277168.1 - 0.27 11.2 3.3 0.27 11.1 0.0 2.6 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 Phasin PF05597.6 XP_011277168.1 - 0.98 9.1 5.0 1.1 8.9 0.3 3.0 3 0 0 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Sua5_yciO_yrdC PF01300.13 XP_011277169.1 - 1.5e-51 174.1 0.0 5.5e-51 172.3 0.0 1.8 2 0 0 2 2 2 1 Telomere recombination SUA5 PF03481.8 XP_011277169.1 - 2.8e-34 117.8 0.0 6.1e-34 116.7 0.0 1.6 2 0 0 2 2 2 1 Putative GTP-binding controlling metal-binding Sugar_tr PF00083.19 XP_011277170.1 - 1.5e-123 412.6 25.5 1.8e-123 412.5 17.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 XP_011277170.1 - 7e-21 74.3 30.6 1.5e-20 73.2 19.4 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_3 PF05977.8 XP_011277170.1 - 0.0046 15.1 13.2 0.016 13.3 2.1 2.1 2 0 0 2 2 2 2 Transmembrane secretion effector HSP9_HSP12 PF04119.7 XP_011277171.1 - 1.2e-21 76.4 5.3 1.2e-21 76.4 3.7 2.4 2 1 0 2 2 2 1 Heat shock protein 9/12 DUF883 PF05957.8 XP_011277171.1 - 0.042 14.2 5.3 0.13 12.6 0.8 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.13 XP_011277171.1 - 0.044 13.2 5.6 0.081 12.4 3.9 1.4 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain GTPase_Cys_C PF12631.2 XP_011277171.1 - 0.12 12.7 2.2 1.2 9.5 1.5 2.1 1 1 0 1 1 1 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE Mt_ATP-synt_B PF05405.9 XP_011277171.1 - 0.16 11.4 1.9 0.38 10.1 0.1 2.1 2 1 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) ApoA-II PF04711.8 XP_011277171.1 - 0.2 11.5 3.1 0.77 9.6 0.3 2.2 2 0 0 2 2 2 0 Apolipoprotein A-II (ApoA-II) YtxH PF12732.2 XP_011277171.1 - 0.22 11.9 9.0 71 3.8 6.3 2.4 1 1 0 1 1 1 0 YtxH-like protein LEA_4 PF02987.11 XP_011277171.1 - 0.5 10.2 2.9 0.7 9.8 0.8 2.1 2 0 0 2 2 2 0 Late embryogenesis abundant protein Acyl-CoA_dh_C PF12806.2 XP_011277171.1 - 0.63 9.9 6.6 3 7.6 0.7 2.1 1 1 1 2 2 2 0 Acetyl-CoA dehydrogenase C-terminal like MT0933_antitox PF14013.1 XP_011277171.1 - 0.9 9.6 11.8 1.2 9.2 5.6 2.9 2 2 0 2 2 2 0 MT0933-like antitoxin protein PEP-utilisers_N PF05524.8 XP_011277171.1 - 2.3 8.0 6.5 5.9 6.7 0.9 2.2 1 1 0 2 2 2 0 PEP-utilising enzyme, N-terminal DUF1903 PF08991.5 XP_011277173.1 - 7.1e-06 26.0 1.9 1.3e-05 25.2 1.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) CHCH PF06747.8 XP_011277173.1 - 6.8e-05 22.6 6.5 0.0001 22.1 4.5 1.3 1 0 0 1 1 1 1 CHCH domain UPF0203 PF05254.7 XP_011277173.1 - 0.0092 15.8 2.2 0.026 14.3 1.4 1.8 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0203) DUF2392 PF10288.4 XP_011277174.1 - 7.1e-24 84.2 0.5 1.9e-23 82.8 0.4 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) ATP_bind_3 PF01171.15 XP_011277174.1 - 0.041 13.3 0.0 0.47 9.9 0.0 2.1 2 0 0 2 2 2 0 PP-loop family Nefa_Nip30_N PF10187.4 XP_011277175.1 - 1.5e-12 47.6 17.0 1.7e-12 47.4 11.8 1.1 1 0 0 1 1 1 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 YvfG PF09628.5 XP_011277175.1 - 0.029 14.5 0.7 0.051 13.7 0.5 1.5 1 0 0 1 1 1 0 YvfG protein PVL_ORF50 PF07768.6 XP_011277175.1 - 0.11 12.4 10.6 0.14 12.1 7.3 1.1 1 0 0 1 1 1 0 PVL ORF-50-like family Trp_dioxygenase PF03301.8 XP_011277175.1 - 0.53 9.3 5.6 0.63 9.0 3.9 1.0 1 0 0 1 1 1 0 Tryptophan 2,3-dioxygenase PDZ_1 PF12812.2 XP_011277177.1 - 3.1e-49 164.7 1.6 9.3e-30 102.3 0.0 4.1 5 0 0 5 5 5 2 PDZ-like domain PDZ_2 PF13180.1 XP_011277177.1 - 1.6e-14 53.5 0.9 3.7e-05 23.5 0.1 3.9 4 0 0 4 4 4 3 PDZ domain PDZ PF00595.19 XP_011277177.1 - 1.1e-13 51.1 0.0 8.8e-06 25.8 0.0 4.3 3 0 0 3 3 3 3 PDZ domain (Also known as DHR or GLGF) Trypsin_2 PF13365.1 XP_011277177.1 - 4.1e-13 49.3 0.5 3e-11 43.3 0.0 2.6 2 0 0 2 2 2 1 Trypsin-like peptidase domain Trypsin PF00089.21 XP_011277177.1 - 9.5e-06 25.3 0.0 2.8e-05 23.8 0.0 1.8 1 1 0 1 1 1 1 Trypsin Tricorn_PDZ PF14685.1 XP_011277177.1 - 2.8e-05 23.8 0.3 0.036 13.8 0.1 3.7 3 0 0 3 3 3 1 Tricorn protease PDZ domain DUF31 PF01732.11 XP_011277177.1 - 0.028 13.7 1.1 0.074 12.3 0.1 2.1 2 0 0 2 2 2 0 Putative peptidase (DUF31) Peptidase_S7 PF00949.16 XP_011277177.1 - 0.036 13.4 0.1 0.08 12.3 0.0 1.5 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease Peptidase_S46 PF10459.4 XP_011277177.1 - 0.15 10.4 0.8 1.5 7.1 0.0 2.0 2 0 0 2 2 2 0 Peptidase S46 ORC6 PF05460.8 XP_011277178.1 - 1.9e-52 178.5 6.5 2.7e-52 178.0 4.5 1.2 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) Poxvirus_B22R_N PF13169.1 XP_011277178.1 - 0.3 11.2 3.9 0.29 11.3 0.4 2.5 2 1 0 2 2 2 0 Poxvirus B22R protein N-terminal ETC_C1_NDUFA4 PF04800.7 XP_011277179.1 - 7.4e-17 61.0 2.9 1.9e-16 59.7 0.9 2.2 2 1 0 2 2 2 1 ETC complex I subunit conserved region N-SET PF11764.3 XP_011277180.1 - 4.2e-33 114.5 0.9 4.2e-33 114.5 0.6 3.7 4 1 0 4 4 4 1 COMPASS (Complex proteins associated with Set1p) component N SET PF00856.23 XP_011277180.1 - 4.7e-23 82.2 0.1 4.7e-23 82.2 0.1 3.6 3 2 0 3 3 3 1 SET domain SET_assoc PF11767.3 XP_011277180.1 - 1.4e-17 62.7 0.2 2.9e-17 61.7 0.1 1.5 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated RRM_1 PF00076.17 XP_011277180.1 - 0.041 13.5 0.1 0.65 9.6 0.0 2.8 2 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MutS_V PF00488.16 XP_011277181.1 - 7e-79 264.5 0.0 1.2e-78 263.7 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 XP_011277181.1 - 2.6e-35 122.0 4.0 5.9e-35 120.9 2.8 1.7 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 XP_011277181.1 - 1.5e-25 89.3 0.1 5.6e-25 87.5 0.0 2.1 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.12 XP_011277181.1 - 1.3e-08 35.0 0.0 4.5e-08 33.2 0.0 2.0 1 0 0 1 1 1 1 MutS domain II AAA_23 PF13476.1 XP_011277181.1 - 0.57 10.4 0.0 0.57 10.4 0.0 4.1 2 1 0 2 2 2 0 AAA domain Gar1 PF04410.9 XP_011277182.1 - 1.3e-44 151.3 0.3 4.7e-44 149.5 0.2 2.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region NDT80_PhoG PF05224.7 XP_011277183.1 - 4.6e-55 186.5 0.1 4.6e-55 186.5 0.0 2.3 2 1 0 2 2 2 1 NDT80 / PhoG like DNA-binding family GNAT_acetyltr_2 PF13718.1 XP_011277184.1 - 9.3e-82 273.1 0.0 1.6e-81 272.3 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 XP_011277184.1 - 8.7e-66 220.9 0.0 3.7e-65 218.8 0.0 2.1 2 1 0 2 2 2 1 Helicase DUF1726 PF08351.6 XP_011277184.1 - 4.8e-42 141.5 0.1 3.8e-41 138.6 0.0 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 XP_011277184.1 - 2.2e-36 123.9 0.3 8.3e-36 122.1 0.2 2.0 1 0 0 1 1 1 1 Possible tRNA binding domain Acetyltransf_7 PF13508.1 XP_011277184.1 - 0.043 13.9 0.0 0.15 12.2 0.0 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PRK PF00485.13 XP_011277185.1 - 0.054 13.0 1.4 0.18 11.3 0.0 2.1 1 1 1 2 2 2 0 Phosphoribulokinase / Uridine kinase family ABC_tran PF00005.22 XP_011277185.1 - 0.11 12.8 0.4 0.19 11.9 0.3 1.7 1 1 0 1 1 1 0 ABC transporter AAA_18 PF13238.1 XP_011277185.1 - 0.11 12.7 0.0 0.11 12.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF59 PF01883.14 XP_011277186.1 - 4.8e-05 23.2 0.0 8.3e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF59 Tom22 PF04281.8 XP_011277188.1 - 9.4e-51 170.9 1.5 1.1e-50 170.7 1.1 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 DUF3813 PF12758.2 XP_011277188.1 - 0.073 13.2 1.9 0.073 13.2 1.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3813) DUF4611 PF15387.1 XP_011277188.1 - 0.15 12.2 3.7 0.26 11.4 2.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) FAM176 PF14851.1 XP_011277188.1 - 0.4 10.3 2.1 0.59 9.7 1.5 1.2 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.7 XP_011277188.1 - 1.5 8.0 5.5 2 7.6 3.8 1.1 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.6 XP_011277188.1 - 1.6 8.5 4.6 0.29 10.9 0.9 1.4 2 0 0 2 2 2 0 RXT2-like, N-terminal DSPc PF00782.15 XP_011277189.1 - 1.7e-13 50.3 0.0 3.1e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 XP_011277189.1 - 5.6e-08 32.4 0.1 3.5e-07 29.7 0.0 2.2 1 1 2 3 3 3 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 XP_011277189.1 - 0.0025 18.0 0.0 0.0046 17.2 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 XP_011277189.1 - 0.0032 17.5 0.0 0.0054 16.7 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPn PF14671.1 XP_011277189.1 - 0.012 15.6 0.0 0.027 14.4 0.0 1.6 1 0 0 1 1 1 0 Dual specificity protein phosphatase, N-terminal half Y_phosphatase2 PF03162.8 XP_011277189.1 - 0.022 14.1 0.1 0.043 13.1 0.1 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family CDKN3 PF05706.7 XP_011277189.1 - 0.047 13.1 0.0 0.081 12.3 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) AD PF09793.4 XP_011277190.1 - 7e-20 70.6 2.0 9.9e-20 70.1 1.4 1.2 1 0 0 1 1 1 1 Anticodon-binding domain Zot PF05707.7 XP_011277190.1 - 0.042 13.3 0.1 0.052 13.0 0.1 1.2 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) DUF3402 PF11882.3 XP_011277191.1 - 6.2e-81 272.5 11.4 6.2e-81 272.5 7.9 3.2 2 1 0 2 2 2 1 Domain of unknown function (DUF3402) N1221 PF07923.8 XP_011277191.1 - 1.2e-57 195.0 0.8 1.2e-57 195.0 0.6 1.5 2 0 0 2 2 2 1 N1221-like protein Spc97_Spc98 PF04130.8 XP_011277192.1 - 8e-68 229.0 23.9 1.1e-67 228.6 16.6 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family DUF4256 PF14066.1 XP_011277193.1 - 0.00029 20.3 0.2 0.0005 19.6 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4256) Pkinase PF00069.20 XP_011277194.1 - 5.3e-37 127.3 0.0 2.1e-36 125.4 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011277194.1 - 3.7e-18 65.5 0.0 5.3e-18 65.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 XP_011277194.1 - 9.5e-06 25.5 0.0 0.0036 17.0 0.0 2.1 2 0 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 XP_011277194.1 - 0.0047 16.0 0.0 0.0082 15.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 XP_011277194.1 - 0.022 13.7 0.0 5.2 5.9 0.0 2.9 3 0 0 3 3 3 0 Kinase-like RabGAP-TBC PF00566.13 XP_011277195.1 - 3.3e-28 98.6 3.2 7.7e-28 97.4 2.2 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain WD40 PF00400.27 XP_011277196.1 - 1e-15 56.8 19.2 8.6e-05 22.2 0.2 6.8 6 1 0 6 6 6 5 WD domain, G-beta repeat Cytochrome-c551 PF10643.4 XP_011277196.1 - 1.1 8.5 2.8 1.7 7.8 2.0 1.2 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 COPI_C PF06957.6 XP_011277196.1 - 1.3 7.4 12.5 2.5 6.5 8.7 1.4 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus CRT10 PF08728.5 XP_011277196.1 - 5.7 4.8 8.3 10 3.9 5.7 1.3 1 0 0 1 1 1 0 CRT10 ABC_tran PF00005.22 XP_011277197.1 - 4.5e-17 62.6 0.7 2e-16 60.5 0.2 2.2 2 1 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 XP_011277197.1 - 1.4e-10 41.6 4.2 9.3e-05 22.5 0.0 2.8 2 1 1 3 3 3 2 AAA domain AAA_15 PF13175.1 XP_011277197.1 - 1.5e-06 27.5 1.5 0.028 13.4 0.0 2.9 2 1 1 3 3 3 2 AAA ATPase domain SMC_N PF02463.14 XP_011277197.1 - 2.3e-05 23.7 0.1 0.027 13.6 0.0 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 XP_011277197.1 - 0.00052 19.2 0.1 0.0009 18.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 XP_011277197.1 - 0.00089 18.7 0.1 0.0017 17.8 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.24 XP_011277197.1 - 0.0056 16.8 0.2 0.11 12.7 0.1 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Epiglycanin_C PF14654.1 XP_011277197.1 - 0.027 14.4 0.0 0.045 13.7 0.0 1.3 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region AAA_17 PF13207.1 XP_011277197.1 - 0.034 14.9 1.1 0.077 13.8 0.8 2.1 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.17 XP_011277197.1 - 0.036 13.5 0.1 0.058 12.8 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_10 PF12846.2 XP_011277197.1 - 0.062 12.7 0.2 0.12 11.7 0.2 1.5 1 0 0 1 1 1 0 AAA-like domain MMR_HSR1 PF01926.18 XP_011277197.1 - 0.086 12.7 0.4 0.16 11.8 0.3 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase PduV-EutP PF10662.4 XP_011277197.1 - 0.1 12.1 0.2 0.18 11.2 0.1 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 XP_011277197.1 - 0.11 13.0 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein AAA_23 PF13476.1 XP_011277197.1 - 0.13 12.5 3.3 0.35 11.1 2.3 1.9 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 XP_011277197.1 - 0.14 11.5 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family Dynamin_N PF00350.18 XP_011277197.1 - 0.23 11.2 1.0 0.41 10.4 0.7 1.4 1 0 0 1 1 1 0 Dynamin family FA_hydroxylase PF04116.8 XP_011277198.1 - 1.3e-11 44.8 20.2 1.3e-11 44.8 14.0 2.4 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily GATA PF00320.22 XP_011277200.1 - 9e-17 60.1 3.4 9e-17 60.1 2.3 2.6 2 0 0 2 2 2 1 GATA zinc finger DUF1752 PF08550.5 XP_011277200.1 - 2e-11 43.2 4.3 2e-11 43.2 3.0 2.2 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1752) PhoD PF09423.5 XP_011277201.1 - 4.5e-25 88.1 0.3 4.8e-23 81.4 0.0 2.8 2 1 1 3 3 3 2 PhoD-like phosphatase DUF3284 PF11687.3 XP_011277201.1 - 0.044 13.5 1.6 0.09 12.5 0.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3284) CN_hydrolase PF00795.17 XP_011277202.1 - 2.3e-25 89.0 0.0 3.2e-25 88.5 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase cobW PF02492.14 XP_011277203.1 - 2.2e-45 154.2 6.0 7.5e-43 146.0 4.1 2.2 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 XP_011277203.1 - 3.3e-19 68.3 0.0 3.7e-15 55.4 0.0 2.5 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain CDC45 PF02724.9 XP_011277203.1 - 0.00011 20.3 5.2 0.00011 20.3 3.6 2.0 2 0 0 2 2 2 1 CDC45-like protein ArgK PF03308.11 XP_011277203.1 - 0.0082 14.9 0.2 0.13 10.9 0.0 2.5 2 1 0 2 2 2 1 ArgK protein LacI PF00356.16 XP_011277203.1 - 0.012 15.1 0.1 0.027 14.0 0.1 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family AAA_33 PF13671.1 XP_011277203.1 - 0.021 14.7 0.1 0.075 12.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 XP_011277203.1 - 0.042 13.3 0.1 0.1 12.1 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 XP_011277203.1 - 0.058 13.7 0.1 0.058 13.7 0.0 3.3 3 1 0 3 3 3 0 AAA domain Daxx PF03344.10 XP_011277203.1 - 0.44 8.9 16.0 0.98 7.8 11.1 1.5 1 0 0 1 1 1 0 Daxx Family MFS_1 PF07690.11 XP_011277204.1 - 2e-30 105.7 27.4 2.9e-30 105.2 19.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily RabGAP-TBC PF00566.13 XP_011277206.1 - 2.3e-49 167.7 0.2 4.6e-49 166.8 0.1 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GRAM PF02893.15 XP_011277206.1 - 3.9e-12 45.5 0.1 1.2e-11 43.8 0.1 2.0 1 0 0 1 1 1 1 GRAM domain EF-hand_7 PF13499.1 XP_011277206.1 - 4.3e-06 26.7 0.4 2.6e-05 24.2 0.2 2.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 XP_011277206.1 - 4.5e-05 22.9 0.3 0.54 10.2 0.0 3.4 2 0 0 2 2 2 2 EF-hand domain Vps36_ESCRT-II PF11605.3 XP_011277206.1 - 0.0009 19.0 0.1 0.0087 15.8 0.0 2.5 2 0 0 2 2 2 1 Vacuolar protein sorting protein 36 Vps36 EF-hand_1 PF00036.27 XP_011277206.1 - 0.012 14.9 0.3 5.3 6.5 0.0 3.1 2 0 0 2 2 2 0 EF hand Telomere_reg-2 PF10193.4 XP_011277207.1 - 2e-29 102.1 1.4 2e-29 102.1 1.0 3.2 4 0 0 4 4 4 1 Telomere length regulation protein DAP PF15228.1 XP_011277207.1 - 0.023 15.4 0.5 0.34 11.6 0.0 2.6 2 0 0 2 2 2 0 Death-associated protein Tom22 PF04281.8 XP_011277207.1 - 0.037 13.5 3.2 4.3 6.8 0.0 2.6 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 LAGLIDADG_WhiA PF14527.1 XP_011277207.1 - 0.053 13.3 2.0 0.37 10.7 0.1 2.8 2 0 0 2 2 2 0 WhiA LAGLIDADG-like domain Peptidase_M16 PF00675.15 XP_011277208.1 - 2.3e-33 115.0 0.1 1.3e-30 106.0 0.0 3.1 3 0 0 3 3 3 2 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 XP_011277208.1 - 1.2e-10 41.4 0.5 5.5e-06 26.1 0.0 4.0 3 1 0 3 3 3 2 Peptidase M16 inactive domain Methyltransf_28 PF02636.12 XP_011277209.1 - 2.7e-64 216.9 0.0 3.9e-64 216.4 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_11 PF08241.7 XP_011277210.1 - 3.8e-06 27.3 0.0 9.9e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 XP_011277210.1 - 0.00023 20.8 0.0 0.0019 17.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 XP_011277210.1 - 0.0023 17.5 0.1 0.0054 16.3 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 XP_011277210.1 - 0.0029 18.1 0.7 0.016 15.7 0.1 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 XP_011277210.1 - 0.028 14.8 1.5 13 6.3 0.0 3.1 3 0 0 3 3 3 0 Methyltransferase domain MetW PF07021.7 XP_011277210.1 - 0.065 12.6 0.0 0.087 12.1 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Pox_Ag35 PF03286.9 XP_011277210.1 - 0.32 10.4 8.0 0.48 9.9 5.5 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Vfa1 PF08432.5 XP_011277210.1 - 0.33 10.9 8.1 0.47 10.4 5.6 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF3987 PF13148.1 XP_011277210.1 - 0.83 8.1 6.2 1.1 7.7 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) PIG-S PF10510.4 XP_011277211.1 - 1.5e-108 363.7 6.3 2e-108 363.3 4.3 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein TAFII28 PF04719.9 XP_011277212.1 - 1.7e-25 88.6 3.8 9e-24 83.0 0.3 2.6 1 1 1 2 2 2 2 hTAFII28-like protein conserved region Slu7 PF11708.3 XP_011277212.1 - 0.0016 18.2 0.6 0.0016 18.2 0.4 1.7 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor BPL_N PF09825.4 XP_011277212.1 - 0.71 8.5 4.1 0.93 8.2 2.8 1.3 1 1 0 1 1 1 0 Biotin-protein ligase, N terminal LCM PF04072.9 XP_011277213.1 - 2.7e-27 95.5 0.0 3.6e-27 95.1 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase DUF1827 PF08860.5 XP_011277213.1 - 1.8 8.7 6.2 0.47 10.5 0.2 2.9 3 2 2 5 5 5 0 Domain of unknown function (DUF1827) DUF4140 PF13600.1 XP_011277214.1 - 0.012 16.0 10.3 0.026 14.9 1.5 2.9 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF4164 PF13747.1 XP_011277214.1 - 0.42 10.7 10.6 0.27 11.3 4.6 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Reo_sigmaC PF04582.7 XP_011277214.1 - 0.51 9.4 9.0 0.72 8.9 6.2 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein OST3_OST6 PF04756.8 XP_011277215.1 - 7.7e-22 77.5 11.0 1.2e-21 76.8 7.6 1.3 1 0 0 1 1 1 1 OST3 / OST6 family Thioredoxin PF00085.15 XP_011277215.1 - 0.00016 21.2 0.0 0.00029 20.4 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin EamA PF00892.15 XP_011277216.1 - 1.3e-13 51.1 29.5 2.3e-08 34.1 3.6 2.5 2 1 1 3 3 3 2 EamA-like transporter family TPT PF03151.11 XP_011277216.1 - 6.6e-10 38.8 19.7 4.9e-05 23.0 1.5 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family DUF914 PF06027.7 XP_011277216.1 - 5.5e-07 28.7 16.0 7.1e-07 28.3 11.1 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) UAA PF08449.6 XP_011277216.1 - 7.5e-07 28.3 15.3 1.1e-06 27.8 10.6 1.2 1 0 0 1 1 1 1 UAA transporter family EmrE PF13536.1 XP_011277216.1 - 0.0044 17.1 4.2 0.0044 17.1 2.9 2.9 1 1 0 2 2 2 1 Multidrug resistance efflux transporter DUF2660 PF10859.3 XP_011277216.1 - 0.013 15.7 0.7 0.031 14.5 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2660) UPF0546 PF10639.4 XP_011277216.1 - 0.49 10.2 7.5 0.075 12.8 0.5 2.8 2 1 2 4 4 4 0 Uncharacterised protein family UPF0546 Imm18 PF15566.1 XP_011277217.1 - 1 8.7 9.4 12 5.2 0.8 4.0 3 1 0 3 3 3 0 Immunity protein 18 IncA PF04156.9 XP_011277217.1 - 1.3 8.6 33.6 0.33 10.5 13.2 2.1 1 1 1 2 2 2 0 IncA protein DUF1514 PF07438.6 XP_011277217.1 - 1.6 8.7 5.7 12 5.8 0.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1514) DUF4259 PF14078.1 XP_011277217.1 - 2.6 8.5 5.5 5 7.6 1.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4259) PIG-P PF08510.7 XP_011277218.1 - 9.2e-30 102.8 5.4 9.2e-30 102.8 3.8 2.8 3 0 0 3 3 3 1 PIG-P Metallophos PF00149.23 XP_011277219.1 - 2.5e-39 134.7 0.1 2.5e-39 134.7 0.1 2.0 2 1 1 3 3 3 1 Calcineurin-like phosphoesterase UDG PF03167.14 XP_011277221.1 - 1.6e-26 92.6 0.1 2.5e-26 91.9 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily DOT1 PF08123.8 XP_011277222.1 - 1.8e-81 272.3 0.2 2.8e-81 271.7 0.2 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_31 PF13847.1 XP_011277222.1 - 5e-06 26.1 0.1 1.9e-05 24.2 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 XP_011277222.1 - 3.8e-05 23.4 0.0 7.2e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 XP_011277222.1 - 0.0057 17.2 0.5 0.013 16.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 XP_011277222.1 - 0.076 13.5 0.0 0.23 11.9 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain CAF-1_p150 PF11600.3 XP_011277222.1 - 0.53 9.6 40.4 1.2 8.4 28.0 1.7 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Pribosyltran PF00156.22 XP_011277223.1 - 1.6e-16 60.1 0.0 2.1e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 XP_011277223.1 - 0.00039 19.6 0.0 0.0005 19.3 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Nse5 PF08691.5 XP_011277224.1 - 2.5e-16 59.3 5.8 2.6e-08 32.8 0.2 2.8 3 0 0 3 3 3 2 DNA repair proteins Nse5 and Nse6 Med13_C PF06333.7 XP_011277225.1 - 7.4e-78 261.9 1.6 7.4e-78 261.9 1.1 2.7 3 0 0 3 3 3 1 Mediator complex subunit 13 C-terminal VID27 PF08553.5 XP_011277225.1 - 2.6 6.1 19.6 0.017 13.3 7.6 1.6 2 0 0 2 2 2 0 VID27 cytoplasmic protein DUF676 PF05057.9 XP_011277226.1 - 7.5e-50 169.2 0.0 1.3e-49 168.4 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase PF00151.14 XP_011277226.1 - 0.015 14.5 0.0 0.031 13.5 0.0 1.4 1 0 0 1 1 1 0 Lipase Abhydrolase_5 PF12695.2 XP_011277226.1 - 0.087 12.5 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.20 XP_011277226.1 - 0.1 12.1 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) Pro_isomerase PF00160.16 XP_011277229.1 - 1.6e-08 34.9 0.4 1.9e-05 24.8 0.0 2.0 1 1 1 2 2 2 2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Spt5-NGN PF03439.8 XP_011277230.1 - 4.4e-24 84.0 0.0 8.4e-24 83.1 0.0 1.5 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.3 XP_011277230.1 - 1.3e-14 54.5 15.3 1.3e-14 54.5 10.6 3.5 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.24 XP_011277230.1 - 1.3e-12 46.8 17.7 0.00063 19.3 0.1 6.2 6 0 0 6 6 6 4 KOW motif NusG PF02357.14 XP_011277230.1 - 0.02 15.1 1.3 0.23 11.7 0.0 2.9 3 0 0 3 3 3 0 Transcription termination factor nusG CTD PF12815.2 XP_011277230.1 - 0.16 12.3 57.5 8.9 6.7 20.9 4.1 1 1 1 2 2 2 0 Spt5 C-terminal nonapeptide repeat binding Spt4 Rad33 PF08730.5 XP_011277231.1 - 3.3e-22 78.7 8.0 2.1e-19 69.6 5.6 2.2 1 1 0 1 1 1 1 Rad33 EMP24_GP25L PF01105.19 XP_011277232.1 - 4.5e-43 147.0 0.1 5.2e-43 146.8 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD EzrA PF06160.7 XP_011277232.1 - 0.044 11.9 0.4 0.057 11.6 0.3 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA M16C_assoc PF08367.6 XP_011277233.1 - 8.7e-74 247.4 0.2 8.7e-74 247.4 0.1 1.8 2 0 0 2 2 2 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 XP_011277233.1 - 6.5e-38 130.2 0.5 4.3e-23 81.9 0.0 3.9 4 0 0 4 4 4 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 XP_011277233.1 - 9.6e-07 28.6 0.0 3e-06 27.0 0.0 1.8 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Plasmid_killer PF05015.8 XP_011277233.1 - 0.052 13.6 0.2 0.86 9.7 0.1 2.8 2 0 0 2 2 2 0 Plasmid maintenance system killer protein AA_kinase PF00696.23 XP_011277234.1 - 5.1e-37 127.6 1.9 5.1e-37 127.6 1.3 1.5 2 0 0 2 2 2 1 Amino acid kinase family PUA PF01472.15 XP_011277234.1 - 1.5e-18 66.2 0.4 4.5e-18 64.7 0.0 2.0 2 0 0 2 2 2 1 PUA domain PIH1 PF08190.7 XP_011277235.1 - 1.4e-29 103.5 4.9 1.7e-29 103.3 3.4 1.1 1 0 0 1 1 1 1 pre-RNA processing PIH1/Nop17 DUF3747 PF12565.3 XP_011277235.1 - 0.016 14.2 0.0 0.027 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3747) PAS_3 PF08447.6 XP_011277236.1 - 0.072 13.2 0.0 1.3 9.2 0.0 2.5 2 0 0 2 2 2 0 PAS fold MatE PF01554.13 XP_011277237.1 - 4.6e-58 195.4 22.7 3.3e-31 108.0 2.4 2.5 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 XP_011277237.1 - 1.2e-07 31.6 7.0 1.2e-07 31.6 4.9 4.6 3 1 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain AATF-Che1 PF13339.1 XP_011277238.1 - 1.2e-31 109.5 2.8 1.2e-31 109.5 1.9 4.3 4 1 0 4 4 4 1 Apoptosis antagonizing transcription factor TRAUB PF08164.7 XP_011277238.1 - 3e-27 94.5 0.1 3e-27 94.5 0.1 3.1 3 0 0 3 3 3 1 Apoptosis-antagonizing transcription factor, C-terminal LTV PF04180.9 XP_011277239.1 - 2.4e-89 300.7 45.0 1.8e-88 297.9 31.2 1.8 1 1 0 1 1 1 1 Low temperature viability protein Aa_trans PF01490.13 XP_011277240.1 - 1.7e-88 296.8 32.0 2e-88 296.6 22.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AAA PF00004.24 XP_011277241.1 - 2.1e-40 137.9 0.0 3.8e-40 137.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 XP_011277241.1 - 4.4e-06 26.8 0.0 0.00094 19.3 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 XP_011277241.1 - 1.6e-05 24.6 0.1 0.00012 21.7 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 XP_011277241.1 - 4.7e-05 23.3 0.0 0.00027 20.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 XP_011277241.1 - 0.00013 22.0 0.0 0.00051 20.0 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.8 XP_011277241.1 - 0.00071 18.5 0.0 0.0012 17.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 XP_011277241.1 - 0.00098 19.9 0.8 0.0023 18.7 0.1 2.2 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.7 XP_011277241.1 - 0.0033 16.5 0.0 0.0057 15.7 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 XP_011277241.1 - 0.0057 16.3 0.1 0.011 15.4 0.1 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 XP_011277241.1 - 0.0082 16.1 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 XP_011277241.1 - 0.0084 16.0 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 XP_011277241.1 - 0.012 14.7 0.0 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.1 XP_011277241.1 - 0.018 14.8 0.0 0.033 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 XP_011277241.1 - 0.022 14.9 0.0 0.054 13.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.1 XP_011277241.1 - 0.024 14.9 0.0 0.055 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 XP_011277241.1 - 0.029 13.8 0.0 0.048 13.0 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_3 PF07726.6 XP_011277241.1 - 0.031 13.9 0.0 0.058 13.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 XP_011277241.1 - 0.032 14.2 0.0 0.071 13.1 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain TIP49 PF06068.8 XP_011277241.1 - 0.036 12.8 0.0 0.065 11.9 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus Mg_chelatase PF01078.16 XP_011277241.1 - 0.042 13.0 0.0 0.088 11.9 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 XP_011277241.1 - 0.067 12.7 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 XP_011277241.1 - 0.092 12.4 0.3 1.8 8.1 0.0 2.5 2 1 0 2 2 2 0 Archaeal ATPase DUF4164 PF13747.1 XP_011277241.1 - 0.1 12.7 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Sigma54_activat PF00158.21 XP_011277241.1 - 0.13 11.7 0.0 0.31 10.4 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_pol_Rbc25 PF08292.7 XP_011277242.1 - 2.8e-42 143.7 0.0 4.6e-42 143.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 XP_011277242.1 - 3.7e-16 59.0 0.0 5.6e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 FAD_binding_2 PF00890.19 XP_011277243.1 - 5.2e-122 407.6 3.7 6.9e-122 407.2 2.5 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 XP_011277243.1 - 4.6e-46 155.8 0.5 7e-46 155.2 0.3 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term GIDA PF01134.17 XP_011277243.1 - 4e-06 25.9 0.3 0.0013 17.6 0.4 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 XP_011277243.1 - 4.5e-06 26.6 5.3 0.0012 18.8 3.7 2.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 XP_011277243.1 - 3e-05 23.0 0.9 0.00068 18.6 0.6 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 XP_011277243.1 - 5.1e-05 22.4 0.2 0.0098 15.0 0.0 2.4 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.14 XP_011277243.1 - 0.0058 15.7 0.1 0.01 14.9 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 XP_011277243.1 - 0.025 13.0 0.0 0.16 10.3 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein DBR1 PF05011.8 XP_011277244.1 - 8.7e-18 64.5 2.4 2e-17 63.4 1.7 1.6 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 XP_011277244.1 - 1.1e-08 34.6 1.0 1.1e-08 34.6 0.7 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 XP_011277244.1 - 0.0033 17.2 0.0 0.027 14.3 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain NAD_binding_1 PF00175.16 XP_011277245.1 - 9.9e-26 90.4 0.0 1.8e-25 89.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 XP_011277245.1 - 1.6e-19 69.8 0.0 2.8e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 XP_011277245.1 - 1.7e-08 34.5 0.0 9e-06 25.6 0.0 2.4 2 0 0 2 2 2 2 Ferric reductase NAD binding domain Carb_kinase PF01256.12 XP_011277246.1 - 3.4e-49 167.3 0.0 4.4e-49 166.9 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.7 XP_011277246.1 - 0.059 12.5 0.0 0.16 11.1 0.0 1.7 1 1 0 1 1 1 0 Phosphomethylpyrimidine kinase DUF3294 PF07957.6 XP_011277247.1 - 2.7e-65 219.9 3.9 3.2e-65 219.6 2.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3294) H-kinase_dim PF02895.9 XP_011277247.1 - 1.8 8.9 5.9 9 6.7 0.2 3.0 2 1 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain PUF PF00806.14 XP_011277248.1 - 1.1e-25 87.5 11.3 0.00064 19.0 0.0 9.4 10 0 0 10 10 10 7 Pumilio-family RNA binding repeat Kdo PF06293.9 XP_011277249.1 - 0.0045 16.0 0.0 0.0086 15.1 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Cpn60_TCP1 PF00118.19 XP_011277250.1 - 1.1e-127 426.6 0.4 1.2e-127 426.4 0.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Vps53_N PF04100.7 XP_011277251.1 - 3.4e-91 305.8 18.0 5.2e-91 305.2 12.5 1.3 1 0 0 1 1 1 1 Vps53-like, N-terminal FHA PF00498.21 XP_011277252.1 - 6.8e-15 54.9 0.1 1.2e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 FHA domain Menin PF05053.8 XP_011277252.1 - 5.5 5.0 5.4 7 4.6 3.7 1.1 1 0 0 1 1 1 0 Menin DEAD PF00270.24 XP_011277253.1 - 8.2e-44 149.0 0.3 2.5e-43 147.4 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF4217 PF13959.1 XP_011277253.1 - 1.9e-24 84.9 0.1 4.9e-24 83.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 XP_011277253.1 - 9e-21 73.5 0.0 2e-20 72.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 XP_011277253.1 - 0.005 16.5 0.0 0.44 10.3 0.0 3.2 4 0 0 4 4 4 1 Part of AAA domain Helicase_C_2 PF13307.1 XP_011277253.1 - 0.02 14.8 0.0 0.051 13.5 0.0 1.6 1 0 0 1 1 1 0 Helicase C-terminal domain Cyclin_N PF00134.18 XP_011277255.1 - 2.8e-13 49.5 1.7 1.1e-09 37.9 0.3 2.5 2 0 0 2 2 2 2 Cyclin, N-terminal domain HlyD_3 PF13437.1 XP_011277255.1 - 0.052 13.8 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 HlyD family secretion protein Cyclin_C PF02984.14 XP_011277255.1 - 0.062 13.2 1.3 0.15 11.9 0.1 2.0 2 1 0 2 2 2 0 Cyclin, C-terminal domain YolD PF08863.5 XP_011277255.1 - 1.6 8.5 9.1 2.8 7.8 0.5 2.8 2 1 1 3 3 3 0 YolD-like protein PPTA PF01239.17 XP_011277256.1 - 4.8e-45 149.0 18.2 4e-09 35.4 0.0 5.4 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat Ubiquitin_3 PF14836.1 XP_011277256.1 - 0.86 9.3 4.1 6.9 6.4 0.0 3.4 4 0 0 4 4 4 0 Ubiquitin-like domain HORMA PF02301.13 XP_011277257.1 - 6.1e-43 146.7 1.4 6.9e-43 146.5 1.0 1.0 1 0 0 1 1 1 1 HORMA domain DUF1649 PF07855.7 XP_011277257.1 - 0.0051 16.4 0.7 0.078 12.6 0.5 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1649) ATG13 PF10033.4 XP_011277257.1 - 0.012 15.1 0.1 0.015 14.7 0.1 1.3 1 0 0 1 1 1 0 Autophagy-related protein 13 Wzt_C PF14524.1 XP_011277257.1 - 0.044 13.4 0.0 0.088 12.5 0.0 1.5 1 0 0 1 1 1 0 Wzt C-terminal domain HSP70 PF00012.15 XP_011277258.1 - 7.9e-263 872.8 16.7 9.1e-263 872.6 11.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 XP_011277258.1 - 4e-18 65.1 4.7 3.7e-17 61.9 1.5 2.2 2 0 0 2 2 2 2 MreB/Mbl protein BcrAD_BadFG PF01869.15 XP_011277258.1 - 9.7e-05 21.7 0.8 0.19 10.9 0.1 2.6 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family Hydantoinase_A PF01968.13 XP_011277258.1 - 0.00027 20.1 5.0 0.0099 15.0 0.1 3.3 2 1 0 3 3 3 1 Hydantoinase/oxoprolinase FGGY_C PF02782.11 XP_011277258.1 - 0.0022 17.6 0.0 0.036 13.6 0.0 2.3 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 XP_011277258.1 - 2.4 8.0 15.2 0.24 11.2 0.6 4.1 3 2 0 3 3 3 0 Cell division protein FtsA dCMP_cyt_deam_1 PF00383.17 XP_011277259.1 - 1.5e-19 69.4 0.0 2.1e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region PSII_Pbs27 PF13326.1 XP_011277259.1 - 0.015 15.2 0.0 0.022 14.7 0.0 1.2 1 0 0 1 1 1 0 Photosystem II Pbs27 Bd3614-deam PF14439.1 XP_011277259.1 - 0.03 14.1 0.2 0.1 12.4 0.2 1.8 1 1 0 1 1 1 0 Bd3614-like deaminase APOBEC_N PF08210.6 XP_011277259.1 - 0.12 11.9 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 APOBEC-like N-terminal domain PX PF00787.19 XP_011277260.1 - 2.8e-20 72.1 0.5 2.8e-20 72.1 0.4 2.7 2 1 1 3 3 3 1 PX domain Vps5 PF09325.5 XP_011277260.1 - 1e-06 28.1 14.8 0.00051 19.3 10.3 2.3 1 1 0 1 1 1 1 Vps5 C terminal like Reo_sigmaC PF04582.7 XP_011277260.1 - 0.0076 15.4 1.6 2.9 6.9 0.6 2.4 1 1 1 2 2 2 2 Reovirus sigma C capsid protein FlaC_arch PF05377.6 XP_011277260.1 - 0.0084 15.9 7.7 0.47 10.3 1.2 3.5 3 0 0 3 3 3 2 Flagella accessory protein C (FlaC) MtrG PF04210.8 XP_011277260.1 - 0.014 15.0 1.9 4.2 7.1 0.1 2.6 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G DUF848 PF05852.6 XP_011277260.1 - 0.018 14.9 1.0 0.018 14.9 0.7 3.4 4 0 0 4 4 4 0 Gammaherpesvirus protein of unknown function (DUF848) BAR PF03114.13 XP_011277260.1 - 0.024 14.1 13.3 0.36 10.3 9.2 2.7 1 1 0 1 1 1 0 BAR domain V-SNARE_C PF12352.3 XP_011277260.1 - 0.027 14.5 1.0 0.46 10.5 0.0 2.4 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Baculo_PEP_C PF04513.7 XP_011277260.1 - 0.98 9.2 7.7 7 6.4 3.6 3.1 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus PTCB-BRCT PF12738.2 XP_011277261.1 - 3.4e-33 113.2 1.0 3.6e-20 71.5 0.2 4.5 4 0 0 4 4 4 3 twin BRCT domain BRCT PF00533.21 XP_011277261.1 - 3.9e-27 94.2 6.5 3.4e-07 30.3 0.1 6.5 6 0 0 6 6 6 5 BRCA1 C Terminus (BRCT) domain SMI1_KNR4 PF09346.5 XP_011277262.1 - 1.3e-23 83.3 0.4 2.2e-23 82.6 0.3 1.4 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) SUKH_6 PF14568.1 XP_011277262.1 - 0.014 15.8 0.9 0.014 15.8 0.7 2.6 1 1 1 2 2 2 0 SMI1-KNR4 cell-wall RhoGAP PF00620.22 XP_011277263.1 - 1.8e-09 37.3 0.1 1.4e-08 34.5 0.1 2.6 1 0 0 1 1 1 1 RhoGAP domain DEP PF00610.16 XP_011277263.1 - 0.041 13.6 0.0 0.27 11.0 0.0 2.4 2 0 0 2 2 2 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Erv26 PF04148.8 XP_011277264.1 - 3.7e-84 281.3 4.7 4.2e-84 281.1 3.3 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 CD20 PF04103.10 XP_011277264.1 - 0.34 10.8 7.0 3.2 7.6 4.0 2.2 1 1 0 1 1 1 0 CD20-like family PetG PF02529.10 XP_011277264.1 - 1.1 8.8 4.6 0.54 9.8 1.1 2.0 2 0 0 2 2 2 0 Cytochrome B6-F complex subunit 5 Cytochrom_C_asm PF01578.15 XP_011277264.1 - 1.5 8.3 9.2 0.37 10.2 2.9 2.3 1 1 1 2 2 2 0 Cytochrome C assembly protein MMR_HSR1 PF01926.18 XP_011277265.1 - 1.3e-17 63.8 0.0 1e-15 57.7 0.0 2.6 2 1 1 3 3 3 1 50S ribosome-binding GTPase DUF258 PF03193.11 XP_011277265.1 - 2.4e-08 33.3 0.0 1.9e-07 30.3 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 XP_011277265.1 - 6.7e-07 28.9 0.0 4.2e-06 26.3 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AIG1 PF04548.11 XP_011277265.1 - 0.0001 21.5 0.0 0.00022 20.4 0.0 1.6 1 0 0 1 1 1 1 AIG1 family FeoB_N PF02421.13 XP_011277265.1 - 0.00019 20.7 0.0 0.00061 19.1 0.0 1.9 1 0 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.5 XP_011277265.1 - 0.00024 20.3 2.1 0.00095 18.4 0.0 2.4 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit Miro PF08477.8 XP_011277265.1 - 0.00053 20.4 1.2 0.0069 16.8 0.0 2.6 2 1 0 2 2 2 1 Miro-like protein MobB PF03205.9 XP_011277265.1 - 0.0029 17.3 0.6 0.0066 16.1 0.0 1.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Septin PF00735.13 XP_011277265.1 - 0.0039 16.2 1.4 0.0047 15.9 0.0 1.8 2 1 0 2 2 2 1 Septin PduV-EutP PF10662.4 XP_011277265.1 - 0.011 15.1 0.3 0.083 12.3 0.1 2.4 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 XP_011277265.1 - 0.048 13.3 0.1 0.048 13.3 0.0 2.6 2 2 0 2 2 2 0 Archaeal ATPase Dynamin_N PF00350.18 XP_011277265.1 - 0.059 13.1 0.2 0.059 13.1 0.1 3.9 3 2 1 4 4 4 0 Dynamin family AAA_29 PF13555.1 XP_011277265.1 - 0.084 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 XP_011277265.1 - 0.086 13.1 0.6 0.84 9.9 0.0 2.4 2 0 0 2 2 2 0 ABC transporter Ras PF00071.17 XP_011277265.1 - 0.087 12.2 1.8 0.13 11.6 0.0 2.1 2 0 0 2 2 2 0 Ras family AAA_18 PF13238.1 XP_011277265.1 - 0.12 12.6 0.8 0.41 10.9 0.0 2.4 2 1 0 2 2 2 0 AAA domain Gar1 PF04410.9 XP_011277266.1 - 5.7e-45 152.5 0.0 5.7e-45 152.5 0.0 2.0 1 1 1 2 2 2 1 Gar1/Naf1 RNA binding region AAA_11 PF13086.1 XP_011277267.1 - 6.2e-11 42.3 2.8 3.8e-10 39.7 0.2 2.9 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 XP_011277267.1 - 0.00018 21.1 0.0 0.00038 20.1 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 XP_011277267.1 - 0.0079 15.7 0.0 0.018 14.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 XP_011277267.1 - 0.014 14.3 0.0 0.028 13.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF258 PF03193.11 XP_011277267.1 - 0.058 12.5 0.0 0.26 10.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Ribosomal_S15 PF00312.17 XP_011277268.1 - 4.1e-21 74.5 0.7 4.1e-21 74.5 0.5 1.9 2 0 0 2 2 2 1 Ribosomal protein S15 DUF3487 PF11990.3 XP_011277268.1 - 0.052 12.9 0.2 0.12 11.7 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3487) Abhydrolase_1 PF00561.15 XP_011277269.1 - 6.7e-19 68.3 0.0 4.4e-18 65.6 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 XP_011277269.1 - 7.8e-08 32.4 0.0 4e-07 30.1 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 XP_011277269.1 - 0.00018 21.0 0.0 0.00032 20.2 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 XP_011277269.1 - 0.0095 15.7 0.0 0.14 11.9 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 XP_011277269.1 - 0.13 11.4 0.0 0.38 9.9 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family Tannase PF07519.6 XP_011277269.1 - 0.16 10.6 0.0 0.24 10.0 0.0 1.2 1 0 0 1 1 1 0 Tannase and feruloyl esterase ABC_membrane PF00664.18 XP_011277270.1 - 9.7e-92 307.2 35.6 3.6e-52 177.4 5.7 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 XP_011277270.1 - 1.7e-51 174.0 0.8 6e-31 107.5 0.2 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 XP_011277270.1 - 1.9e-10 40.3 10.5 0.00012 21.3 1.8 4.3 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 XP_011277270.1 - 1.5e-08 34.8 0.5 0.0062 16.5 0.0 2.7 3 0 0 3 3 2 2 AAA ATPase domain AAA_29 PF13555.1 XP_011277270.1 - 4.4e-05 22.9 0.6 0.26 10.8 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 XP_011277270.1 - 0.00026 20.4 0.1 0.24 10.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 XP_011277270.1 - 0.00029 20.7 0.3 0.52 10.2 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF87 PF01935.12 XP_011277270.1 - 0.00035 20.4 4.4 0.78 9.5 0.1 3.7 3 0 0 3 3 3 2 Domain of unknown function DUF87 AAA_10 PF12846.2 XP_011277270.1 - 0.00063 19.2 2.2 2.1 7.7 0.0 3.8 4 1 0 4 4 4 2 AAA-like domain DUF258 PF03193.11 XP_011277270.1 - 0.00071 18.8 0.3 0.25 10.4 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Miro PF08477.8 XP_011277270.1 - 0.0019 18.7 2.5 0.94 9.9 0.0 3.4 3 0 0 3 3 3 1 Miro-like protein AAA_30 PF13604.1 XP_011277270.1 - 0.003 17.1 1.5 0.25 10.8 0.2 2.8 2 1 0 2 2 2 1 AAA domain AAA_23 PF13476.1 XP_011277270.1 - 0.0072 16.6 5.0 1.3 9.3 0.3 3.4 3 1 0 3 3 3 2 AAA domain T2SE PF00437.15 XP_011277270.1 - 0.03 13.2 0.5 0.26 10.1 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein MobB PF03205.9 XP_011277270.1 - 0.038 13.7 0.8 6.7 6.4 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AIG1 PF04548.11 XP_011277270.1 - 0.051 12.6 2.6 0.68 8.9 0.1 3.0 3 0 0 3 3 3 0 AIG1 family FtsK_SpoIIIE PF01580.13 XP_011277270.1 - 0.091 12.2 0.1 5.6 6.3 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family IstB_IS21 PF01695.12 XP_011277270.1 - 0.095 12.1 0.3 4.5 6.6 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein Zeta_toxin PF06414.7 XP_011277270.1 - 0.11 11.5 0.7 5.5 6.0 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_18 PF13238.1 XP_011277270.1 - 0.21 11.9 1.4 9.1 6.5 0.0 3.1 3 0 0 3 3 2 0 AAA domain NACHT PF05729.7 XP_011277270.1 - 0.3 10.7 3.7 0.37 10.4 0.0 2.8 4 0 0 4 4 4 0 NACHT domain AAA_22 PF13401.1 XP_011277270.1 - 0.43 10.7 3.3 2.5 8.2 0.0 3.1 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.1 XP_011277270.1 - 0.8 10.5 2.6 24 5.7 0.8 3.3 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 XP_011277270.1 - 1.2 8.9 5.3 6.4 6.5 0.2 3.3 3 0 0 3 3 3 0 Dynamin family Pkinase PF00069.20 XP_011277271.1 - 2.1e-72 243.4 0.0 2.6e-72 243.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011277271.1 - 2e-31 108.9 0.0 2.8e-31 108.5 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 XP_011277271.1 - 6.7e-06 25.3 0.1 2.6e-05 23.4 0.0 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 XP_011277271.1 - 0.00018 20.5 0.0 0.011 14.7 0.0 2.2 1 1 1 2 2 2 2 Kinase-like APH PF01636.18 XP_011277271.1 - 0.00027 20.7 0.1 0.0041 16.8 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 XP_011277271.1 - 0.071 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Flocculin_t3 PF13928.1 XP_011277272.1 - 1.2e-15 57.3 24.9 1.2e-15 57.3 17.3 2.6 2 0 0 2 2 2 1 Flocculin type 3 repeat AcetylCoA_hyd_C PF13336.1 XP_011277272.1 - 0.26 10.9 2.0 0.51 9.9 1.4 1.5 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase C-terminal domain BTB_2 PF02214.17 XP_011277273.1 - 0.00016 21.8 0.5 0.0047 17.1 0.1 2.9 3 0 0 3 3 3 1 BTB/POZ domain Redoxin PF08534.5 XP_011277274.1 - 1.3e-34 118.8 0.0 1.4e-34 118.7 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 XP_011277274.1 - 6.3e-15 54.9 0.0 8.5e-15 54.5 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family TraG-D_C PF12696.2 XP_011277274.1 - 0.005 16.7 0.0 0.0062 16.4 0.0 1.2 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG Slx4 PF09494.5 XP_011277275.1 - 1.7e-12 46.8 3.0 3.4e-12 45.9 0.5 2.5 2 0 0 2 2 2 1 Slx4 endonuclease DUF2424 PF10340.4 XP_011277276.1 - 4.3e-37 127.6 0.3 5.2e-37 127.3 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_3 PF07859.8 XP_011277276.1 - 2.3e-25 89.4 0.0 3.4e-25 88.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 XP_011277276.1 - 0.00037 20.2 0.0 0.00057 19.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 XP_011277276.1 - 0.061 12.0 0.0 2.1 6.9 0.0 2.1 2 0 0 2 2 2 0 Carboxylesterase family Peptidase_M28 PF04389.12 XP_011277277.1 - 3.4e-20 72.5 0.0 6e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.10 XP_011277277.1 - 1.5e-15 56.8 0.0 3.4e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.17 XP_011277277.1 - 3.2e-11 42.7 0.1 8.5e-11 41.4 0.0 1.7 1 0 0 1 1 1 1 PA domain Nicastrin PF05450.10 XP_011277277.1 - 0.005 16.1 0.0 0.013 14.7 0.0 1.7 1 0 0 1 1 1 1 Nicastrin Peptidase_M20 PF01546.23 XP_011277277.1 - 0.039 13.4 0.0 0.1 12.1 0.0 1.6 2 0 0 2 2 2 0 Peptidase family M20/M25/M40 ATP-synt_G PF04718.10 XP_011277278.1 - 1.8e-29 102.4 1.0 1.9e-29 102.3 0.2 1.4 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit Nckap1 PF09735.4 XP_011277278.1 - 0.086 10.3 0.0 0.1 10.0 0.0 1.0 1 0 0 1 1 1 0 Membrane-associated apoptosis protein DEAD PF00270.24 XP_011277279.1 - 9.3e-46 155.3 0.5 2.5e-45 153.9 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 XP_011277279.1 - 1.5e-27 95.2 0.6 9.6e-27 92.6 0.2 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 XP_011277279.1 - 0.0047 17.0 0.1 0.013 15.6 0.1 1.8 1 0 0 1 1 1 1 AAA domain CbiC PF02570.10 XP_011277279.1 - 0.055 12.8 0.1 2.9 7.2 0.0 2.3 2 0 0 2 2 2 0 Precorrin-8X methylmutase Helicase_C_2 PF13307.1 XP_011277279.1 - 0.056 13.4 0.2 0.25 11.2 0.0 2.2 2 0 0 2 2 2 0 Helicase C-terminal domain Ribonucleas_3_3 PF14622.1 XP_011277280.1 - 1.7e-22 79.7 0.1 2.5e-22 79.2 0.1 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 XP_011277280.1 - 0.0019 18.6 0.0 0.0044 17.4 0.0 1.7 1 0 0 1 1 1 1 Ribonuclease III domain TauD PF02668.11 XP_011277281.1 - 2.1e-37 129.1 0.8 3e-35 122.1 0.5 2.1 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family adh_short PF00106.20 XP_011277282.1 - 1.1e-20 74.1 0.0 1.5e-20 73.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 XP_011277282.1 - 2.7e-16 60.0 0.1 3.1e-16 59.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 XP_011277282.1 - 1.5e-11 44.3 0.0 2.3e-11 43.7 0.0 1.3 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 XP_011277282.1 - 3.6e-05 23.8 0.0 6.2e-05 23.0 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding Pneumovirus_M2 PF06436.6 XP_011277282.1 - 0.0071 15.5 0.0 0.013 14.6 0.0 1.5 1 0 0 1 1 1 1 Pneumovirus matrix protein 2 (M2) Herpes_U30 PF04523.8 XP_011277282.1 - 0.02 12.3 0.1 0.03 11.7 0.0 1.2 1 0 0 1 1 1 0 Herpes virus tegument protein U30 Sigma70_r1_1 PF03979.9 XP_011277282.1 - 0.027 14.3 0.4 4.4 7.3 0.0 2.3 2 0 0 2 2 2 0 Sigma-70 factor, region 1.1 DPRP PF04244.8 XP_011277282.1 - 0.048 13.1 0.1 1 8.8 0.0 2.2 2 0 0 2 2 2 0 Deoxyribodipyrimidine photo-lyase-related protein FAD_binding_1 PF00667.15 XP_011277282.1 - 0.087 12.2 0.4 4.5 6.6 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain 3H PF02829.9 XP_011277282.1 - 0.091 12.7 0.1 0.27 11.2 0.0 1.8 2 0 0 2 2 2 0 3H domain SLH PF00395.15 XP_011277284.1 - 0.12 12.1 0.5 0.32 10.7 0.0 1.9 2 0 0 2 2 2 0 S-layer homology domain Epimerase PF01370.16 XP_011277285.1 - 2.7e-10 40.1 0.0 4e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 XP_011277285.1 - 3.2e-06 26.9 0.0 5.2e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 XP_011277285.1 - 1e-05 24.4 0.0 1.6e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 XP_011277285.1 - 2.1e-05 24.5 0.0 3.9e-05 23.6 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 XP_011277285.1 - 2.6e-05 24.3 0.1 6.7e-05 22.9 0.1 1.7 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 XP_011277285.1 - 0.00055 18.9 0.1 0.0014 17.5 0.1 1.7 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 XP_011277285.1 - 0.0089 15.2 0.1 0.014 14.6 0.1 1.4 1 1 0 1 1 1 1 NmrA-like family adh_short_C2 PF13561.1 XP_011277285.1 - 0.026 14.3 0.0 0.043 13.5 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 XP_011277285.1 - 0.032 13.1 0.1 0.046 12.6 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Grp1_Fun34_YaaH PF01184.14 XP_011277286.1 - 7e-86 286.8 15.6 8.3e-86 286.6 10.8 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Metallophos PF00149.23 XP_011277287.1 - 9.2e-40 136.1 0.2 1.2e-39 135.8 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase KaiC PF06745.8 XP_011277288.1 - 1.4e-09 37.4 0.0 3e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 KaiC Rad51 PF08423.6 XP_011277288.1 - 2.8e-06 26.4 0.0 4.9e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Rad51 Arch_ATPase PF01637.13 XP_011277288.1 - 3.2e-06 26.9 0.1 1.3e-05 25.0 0.1 2.0 1 0 0 1 1 1 1 Archaeal ATPase RecA PF00154.16 XP_011277288.1 - 0.00022 20.3 0.0 0.00035 19.7 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.1 XP_011277288.1 - 0.0051 16.2 0.0 0.03 13.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 XP_011277288.1 - 0.0054 16.8 0.0 0.015 15.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 XP_011277288.1 - 0.0058 16.5 0.3 0.034 14.0 0.1 2.5 2 1 0 2 2 2 1 AAA domain Miro PF08477.8 XP_011277288.1 - 0.072 13.5 0.0 0.26 11.7 0.0 2.1 1 1 0 1 1 1 0 Miro-like protein AAA_33 PF13671.1 XP_011277288.1 - 0.13 12.1 0.0 0.38 10.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain Glyco_transf_20 PF00982.16 XP_011277289.1 - 3.5e-152 507.1 3.3 4.7e-152 506.7 2.3 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 XP_011277289.1 - 5.1e-78 261.2 0.0 9.2e-78 260.3 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase PPV_E1_N PF00524.13 XP_011277289.1 - 0.19 11.9 2.8 0.42 10.8 0.1 2.5 2 0 0 2 2 2 0 E1 Protein, N terminal domain TBP PF00352.16 XP_011277291.1 - 1.2e-70 232.8 0.1 1.5e-35 120.4 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 XP_011277291.1 - 0.00019 21.4 0.0 0.83 9.7 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) UCH PF00443.24 XP_011277292.1 - 8.2e-53 179.2 0.7 8.2e-53 179.2 0.5 2.8 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase SWIM PF04434.12 XP_011277293.1 - 0.0075 15.7 1.1 0.027 13.9 0.1 2.1 2 0 0 2 2 2 1 SWIM zinc finger Adap_comp_sub PF00928.16 XP_011277294.1 - 5.4e-93 310.8 1.4 6.5e-93 310.6 1.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 XP_011277294.1 - 2.3e-07 30.6 0.1 4.2e-07 29.7 0.1 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.4 XP_011277294.1 - 0.0017 17.6 0.0 0.0026 17.0 0.0 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain DUF2458 PF10454.4 XP_011277295.1 - 2e-11 43.9 11.9 8.6e-08 32.1 1.8 2.6 2 1 1 3 3 3 2 Protein of unknown function (DUF2458) NLE PF08154.7 XP_011277295.1 - 0.026 14.5 0.7 0.058 13.4 0.5 1.6 1 0 0 1 1 1 0 NLE (NUC135) domain DUF2422 PF10337.4 XP_011277295.1 - 0.065 12.0 1.0 0.074 11.8 0.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) Utp12 PF04003.7 XP_011277295.1 - 0.087 12.7 0.1 0.24 11.3 0.0 1.8 2 0 0 2 2 2 0 Dip2/Utp12 Family UBX PF00789.15 XP_011277295.1 - 0.18 11.9 2.9 5.5 7.1 0.1 2.5 1 1 0 2 2 2 0 UBX domain MIS13 PF08202.6 XP_011277295.1 - 0.23 10.4 7.1 0.28 10.2 4.9 1.2 1 0 0 1 1 1 0 Mis12-Mtw1 protein family Syntaxin PF00804.20 XP_011277295.1 - 1.5 9.0 6.7 1.1 9.4 1.1 2.4 1 1 1 2 2 2 0 Syntaxin PRESAN PF09687.5 XP_011277295.1 - 5 7.2 25.3 2.1 8.4 11.1 2.7 1 1 1 2 2 2 0 Plasmodium RESA N-terminal Cortex-I_coil PF09304.5 XP_011277295.1 - 8.1 6.5 8.1 6.7 6.8 0.9 2.7 2 1 1 3 3 3 0 Cortexillin I, coiled coil RRM_1 PF00076.17 XP_011277296.1 - 8.1e-21 73.4 0.1 1.2e-20 72.8 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 XP_011277296.1 - 2.6e-14 52.9 0.0 4.2e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 XP_011277296.1 - 2.9e-08 33.4 0.0 4.1e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peripla_BP_4 PF13407.1 XP_011277296.1 - 0.059 12.7 0.3 0.16 11.2 0.1 1.6 1 1 1 2 2 2 0 Periplasmic binding protein domain Nop16 PF09420.5 XP_011277297.1 - 4.9e-56 189.3 11.1 5.6e-56 189.1 7.7 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 CAP_assoc_N PF14504.1 XP_011277297.1 - 0.043 13.5 1.1 0.078 12.7 0.8 1.3 1 0 0 1 1 1 0 CAP-associated N-terminal PrmA PF06325.8 XP_011277297.1 - 0.057 12.5 0.8 0.074 12.1 0.5 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) PMI_typeI PF01238.16 XP_011277298.1 - 7.5e-157 522.0 0.0 8.5e-157 521.8 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.6 XP_011277298.1 - 0.022 14.2 0.0 7.8 6.0 0.0 2.3 2 0 0 2 2 2 0 Cupin domain AraC_binding PF02311.14 XP_011277298.1 - 0.077 12.6 0.0 4.4 6.9 0.0 2.3 2 0 0 2 2 2 0 AraC-like ligand binding domain NTF2 PF02136.15 XP_011277299.1 - 1.9e-28 99.1 0.2 2.3e-28 98.9 0.2 1.1 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF3210 PF11489.3 XP_011277300.1 - 1.1e-16 60.7 62.8 1.1e-16 60.7 43.6 4.7 3 2 0 4 4 4 2 Protein of unknown function (DUF3210) Glyco_hydro_72 PF03198.9 XP_011277301.1 - 3.5e-140 466.4 4.6 4.3e-140 466.1 3.2 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 XP_011277301.1 - 0.00049 19.3 0.1 0.005 16.0 0.0 2.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.12 XP_011277301.1 - 0.00066 18.6 0.1 0.0014 17.6 0.1 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_17 PF00332.13 XP_011277301.1 - 0.0072 15.4 0.0 0.011 14.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Adenine_glyco PF03352.8 XP_011277301.1 - 0.086 12.3 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Methyladenine glycosylase DUF1517 PF07466.6 XP_011277301.1 - 3 6.7 7.9 4.9 6.0 5.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Hap4_Hap_bind PF10297.4 XP_011277302.1 - 9.7e-09 34.7 7.3 2.3e-08 33.5 5.1 1.7 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.16 XP_011277302.1 - 9.1e-07 28.7 19.9 6.4e-06 26.0 9.4 2.9 1 1 1 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.10 XP_011277302.1 - 5.3 6.9 17.3 9.6 6.1 10.2 2.9 1 1 1 2 2 2 0 Basic region leucine zipper Pet127 PF08634.5 XP_011277303.1 - 1.2e-104 349.2 4.9 3.2e-104 347.9 3.4 1.7 1 0 0 1 1 1 1 Mitochondrial protein Pet127 PQ-loop PF04193.9 XP_011277304.1 - 1.5e-10 40.4 11.4 7.4e-10 38.2 1.6 3.0 3 0 0 3 3 3 2 PQ loop repeat ER_lumen_recept PF00810.13 XP_011277304.1 - 0.00014 22.3 0.3 0.00014 22.3 0.2 2.9 3 1 0 3 3 3 1 ER lumen protein retaining receptor UAA PF08449.6 XP_011277305.1 - 9.2e-91 303.9 16.5 1.1e-90 303.6 11.5 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 XP_011277305.1 - 4.3e-08 32.9 7.1 4.3e-08 32.9 4.9 2.5 2 1 0 2 2 2 1 Triose-phosphate Transporter family DUF4131 PF13567.1 XP_011277305.1 - 0.00071 19.0 0.8 1.6 8.1 0.0 3.2 2 1 0 3 3 3 2 Domain of unknown function (DUF4131) EamA PF00892.15 XP_011277305.1 - 0.01 15.8 39.6 0.017 15.1 8.6 3.8 2 2 2 4 4 4 0 EamA-like transporter family DUF4231 PF14015.1 XP_011277305.1 - 0.27 11.2 0.0 0.27 11.2 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) Thioredoxin PF00085.15 XP_011277306.1 - 3.7e-21 74.7 0.0 3e-17 62.1 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.1 XP_011277306.1 - 1.2e-05 25.2 10.7 0.052 13.3 0.6 4.3 3 1 1 4 4 4 3 Thioredoxin-like domain Thioredoxin_4 PF13462.1 XP_011277306.1 - 0.0043 17.0 0.0 0.01 15.8 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 XP_011277306.1 - 0.49 10.5 5.9 1.1 9.4 0.0 4.0 4 0 0 4 4 4 0 Thioredoxin-like Gti1_Pac2 PF09729.4 XP_011277307.1 - 3.6e-61 205.9 1.6 3.6e-61 205.9 1.1 1.6 2 0 0 2 2 2 1 Gti1/Pac2 family Mito_carr PF00153.22 XP_011277308.1 - 4.1e-72 237.9 2.8 1.5e-25 88.6 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein ARD PF03079.9 XP_011277309.1 - 1.4e-40 138.7 0.6 1.7e-40 138.5 0.4 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 XP_011277309.1 - 4.5e-08 32.4 0.0 7.8e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 XP_011277309.1 - 1.2e-05 25.0 0.0 1.6e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain GPI PF06560.6 XP_011277309.1 - 0.019 14.0 0.0 0.024 13.6 0.0 1.2 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) Cupin_1 PF00190.17 XP_011277309.1 - 0.14 11.5 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Cupin Prefoldin_2 PF01920.15 XP_011277310.1 - 1.4e-18 66.5 7.9 1.6e-18 66.3 5.5 1.0 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.12 XP_011277310.1 - 0.00034 20.2 5.1 0.11 12.1 0.1 2.1 1 1 1 2 2 2 2 Prefoldin subunit Filament PF00038.16 XP_011277310.1 - 0.0053 16.2 2.2 0.066 12.6 1.5 1.9 1 1 0 1 1 1 1 Intermediate filament protein ING PF12998.2 XP_011277310.1 - 0.0084 16.3 1.7 0.014 15.6 1.1 1.4 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding STAT_alpha PF01017.15 XP_011277310.1 - 0.0088 15.7 5.2 0.014 15.1 3.6 1.3 1 1 0 1 1 1 1 STAT protein, all-alpha domain Seryl_tRNA_N PF02403.17 XP_011277310.1 - 0.018 15.0 5.9 0.2 11.6 1.3 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain ALIX_LYPXL_bnd PF13949.1 XP_011277310.1 - 0.022 13.7 1.2 0.026 13.5 0.8 1.1 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV DASH_Dad3 PF08656.5 XP_011277310.1 - 0.038 13.6 5.4 1.2 8.8 0.9 2.1 2 0 0 2 2 2 0 DASH complex subunit Dad3 FTO_CTD PF12934.2 XP_011277310.1 - 0.042 13.4 0.1 0.049 13.1 0.1 1.1 1 0 0 1 1 1 0 FTO C-terminal domain RasGEF_N_2 PF14663.1 XP_011277310.1 - 0.054 13.4 0.3 0.08 12.8 0.2 1.4 1 1 0 1 1 1 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Baculo_PEP_C PF04513.7 XP_011277310.1 - 0.058 13.2 2.5 3.8 7.3 0.1 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus GAS PF13851.1 XP_011277310.1 - 0.061 12.5 6.2 0.09 11.9 4.3 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding WXG100 PF06013.7 XP_011277310.1 - 0.069 13.1 0.2 12 5.9 0.1 2.2 2 0 0 2 2 2 0 Proteins of 100 residues with WXG Sas10_Utp3 PF04000.10 XP_011277310.1 - 0.097 12.8 1.0 13 6.0 0.0 2.2 2 0 0 2 2 2 0 Sas10/Utp3/C1D family ICA69 PF04629.9 XP_011277310.1 - 0.11 12.4 0.7 0.18 11.7 0.5 1.4 1 1 0 1 1 1 0 Islet cell autoantigen ICA69, C-terminal domain Poxvirus PF06227.7 XP_011277310.1 - 0.14 11.6 3.0 0.13 11.8 0.3 1.8 1 1 1 2 2 2 0 dsDNA Poxvirus WEMBL PF05701.6 XP_011277310.1 - 0.15 10.5 4.4 0.19 10.1 3.0 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light BLOC1_2 PF10046.4 XP_011277310.1 - 0.16 12.1 8.5 0.19 11.8 2.6 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 7TMR-HDED PF07697.6 XP_011277310.1 - 0.16 11.6 3.3 0.21 11.3 2.3 1.2 1 0 0 1 1 1 0 7TM-HD extracellular Rootletin PF15035.1 XP_011277310.1 - 0.17 11.8 4.6 1.3 9.0 3.2 1.9 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF948 PF06103.6 XP_011277310.1 - 0.17 11.7 4.2 1.9 8.4 0.1 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF342 PF03961.8 XP_011277310.1 - 0.27 9.5 7.8 0.86 7.9 5.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF342) YvrJ PF12841.2 XP_011277310.1 - 0.33 10.2 1.9 6.6 6.1 0.1 2.5 2 1 0 2 2 2 0 YvrJ protein family SAS4 PF15460.1 XP_011277310.1 - 0.33 10.8 7.0 0.56 10.1 0.6 2.2 1 1 1 2 2 2 0 Something about silencing, SAS, complex subunit 4 Spc24 PF08286.6 XP_011277310.1 - 0.39 10.4 8.2 1.4 8.5 1.5 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 IFT57 PF10498.4 XP_011277310.1 - 0.4 9.3 7.6 1.5 7.5 1.8 2.0 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 IncA PF04156.9 XP_011277310.1 - 0.43 10.1 3.9 0.91 9.0 0.7 1.9 2 0 0 2 2 2 0 IncA protein DivIVA PF05103.8 XP_011277310.1 - 0.44 10.6 4.9 2.1 8.4 3.4 1.8 1 1 0 1 1 1 0 DivIVA protein Fib_alpha PF08702.5 XP_011277310.1 - 0.57 10.2 7.4 5 7.2 1.6 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF4298 PF14131.1 XP_011277310.1 - 0.6 10.0 4.6 3.2 7.6 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) TcdB_N PF12918.2 XP_011277310.1 - 0.63 10.1 7.4 1.5 8.9 0.6 2.9 2 1 1 3 3 3 0 TcdB toxin N-terminal helical domain 4HB_MCP_1 PF12729.2 XP_011277310.1 - 0.67 9.2 8.2 3.9 6.7 1.5 2.1 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction DUF3847 PF12958.2 XP_011277310.1 - 0.8 9.5 5.7 1.2 8.9 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) TMF_TATA_bd PF12325.3 XP_011277310.1 - 0.84 9.3 5.8 7 6.3 1.5 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Shugoshin_N PF07558.6 XP_011277310.1 - 0.89 9.3 8.9 5.7 6.7 1.7 2.5 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region DUF1664 PF07889.7 XP_011277310.1 - 1.3 8.8 5.7 9.7 6.0 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF2762 PF10960.3 XP_011277310.1 - 1.8 8.3 7.9 0.42 10.3 1.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2762) Med3 PF11593.3 XP_011277310.1 - 2.2 7.4 5.7 1.6 7.8 1.2 1.9 1 1 1 2 2 2 0 Mediator complex subunit 3 fungal DivIC PF04977.10 XP_011277310.1 - 3.5 7.1 9.8 1.2 8.6 2.5 2.1 2 0 0 2 2 2 0 Septum formation initiator Ax_dynein_light PF10211.4 XP_011277310.1 - 4 7.2 8.5 0.62 9.8 1.8 1.9 2 0 0 2 2 2 0 Axonemal dynein light chain FlaC_arch PF05377.6 XP_011277310.1 - 4.3 7.2 7.9 9.1 6.2 0.4 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF904 PF06005.7 XP_011277310.1 - 6.4 7.1 8.7 66 3.8 6.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF904) DDOST_48kD PF03345.9 XP_011277311.1 - 3.3e-133 444.3 0.3 3.7e-133 444.1 0.2 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta DUF948 PF06103.6 XP_011277312.1 - 0.0057 16.4 2.5 0.031 14.1 0.3 2.0 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF948) MtrG PF04210.8 XP_011277312.1 - 0.012 15.2 3.9 1 9.0 0.3 2.4 1 1 1 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G Hemerythrin PF01814.18 XP_011277312.1 - 0.013 15.6 0.6 0.014 15.5 0.4 1.1 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain Vps5 PF09325.5 XP_011277312.1 - 0.014 14.6 3.7 0.015 14.5 2.6 1.1 1 0 0 1 1 1 0 Vps5 C terminal like AKNA PF12443.3 XP_011277312.1 - 0.016 15.2 2.4 0.023 14.7 1.6 1.4 1 1 0 1 1 1 0 AT-hook-containing transcription factor zf-C4H2 PF10146.4 XP_011277312.1 - 0.016 15.2 5.4 0.018 15.0 3.7 1.0 1 0 0 1 1 1 0 Zinc finger-containing protein DUF2130 PF09903.4 XP_011277312.1 - 0.016 13.9 3.5 0.017 13.8 2.5 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2130) DUF2408 PF10303.4 XP_011277312.1 - 0.017 15.2 3.4 0.024 14.7 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Spectrin PF00435.16 XP_011277312.1 - 0.018 15.3 5.5 0.031 14.5 2.9 1.7 1 1 1 2 2 2 0 Spectrin repeat PilJ PF13675.1 XP_011277312.1 - 0.021 15.1 0.9 0.026 14.8 0.6 1.2 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term DASH_Dad1 PF08649.5 XP_011277312.1 - 0.021 14.4 0.4 0.032 13.9 0.3 1.3 1 0 0 1 1 1 0 DASH complex subunit Dad1 MCPsignal PF00015.16 XP_011277312.1 - 0.022 14.2 0.5 0.022 14.2 0.4 1.0 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain WXG100 PF06013.7 XP_011277312.1 - 0.025 14.5 1.8 0.79 9.7 0.2 2.3 1 1 1 2 2 2 0 Proteins of 100 residues with WXG Exonuc_VII_S PF02609.11 XP_011277312.1 - 0.025 14.3 4.0 0.095 12.4 0.1 2.3 2 0 0 2 2 2 0 Exonuclease VII small subunit HsbA PF12296.3 XP_011277312.1 - 0.028 14.2 0.0 0.045 13.6 0.0 1.3 1 1 0 1 1 1 0 Hydrophobic surface binding protein A Tropomyosin PF00261.15 XP_011277312.1 - 0.029 13.4 8.0 0.044 12.8 5.6 1.3 1 1 0 1 1 1 0 Tropomyosin V-SNARE PF05008.10 XP_011277312.1 - 0.03 14.4 5.6 0.036 14.2 3.9 1.2 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus FlaC_arch PF05377.6 XP_011277312.1 - 0.032 14.1 5.0 0.19 11.6 3.5 2.0 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF4208 PF13907.1 XP_011277312.1 - 0.034 14.3 3.9 0.042 14.0 2.6 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4208) ALIX_LYPXL_bnd PF13949.1 XP_011277312.1 - 0.034 13.1 4.4 0.044 12.7 3.0 1.2 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV DUF4164 PF13747.1 XP_011277312.1 - 0.037 14.1 5.2 0.045 13.8 3.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) BLOC1_2 PF10046.4 XP_011277312.1 - 0.041 14.0 4.0 0.052 13.6 2.8 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 EzrA PF06160.7 XP_011277312.1 - 0.047 11.8 5.2 0.065 11.4 3.6 1.3 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA Arfaptin PF06456.8 XP_011277312.1 - 0.049 12.9 2.4 0.053 12.8 1.6 1.1 1 0 0 1 1 1 0 Arfaptin-like domain TENA_THI-4 PF03070.11 XP_011277312.1 - 0.054 13.2 0.4 0.063 13.0 0.3 1.1 1 0 0 1 1 1 0 TENA/THI-4/PQQC family OEP PF02321.13 XP_011277312.1 - 0.06 12.9 1.7 0.07 12.7 1.2 1.1 1 0 0 1 1 1 0 Outer membrane efflux protein K-box PF01486.12 XP_011277312.1 - 0.061 13.1 5.6 0.08 12.7 3.9 1.2 1 0 0 1 1 1 0 K-box region YkyA PF10368.4 XP_011277312.1 - 0.063 12.6 7.5 0.065 12.5 5.2 1.1 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein Vps51 PF08700.6 XP_011277312.1 - 0.067 13.0 5.2 0.16 11.8 0.5 2.1 1 1 1 2 2 2 0 Vps51/Vps67 DUF1664 PF07889.7 XP_011277312.1 - 0.072 12.8 1.9 0.085 12.6 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF1978 PF09321.5 XP_011277312.1 - 0.073 12.5 5.2 0.17 11.3 3.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1978) BetR PF08667.5 XP_011277312.1 - 0.095 12.6 0.2 0.11 12.4 0.1 1.1 1 0 0 1 1 1 0 BetR domain GAS PF13851.1 XP_011277312.1 - 0.098 11.8 9.4 0.11 11.7 6.5 1.0 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding KxDL PF10241.4 XP_011277312.1 - 0.11 12.4 1.6 0.98 9.3 0.2 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein Laminin_II PF06009.7 XP_011277312.1 - 0.11 12.2 3.4 0.41 10.3 1.8 1.8 1 1 0 1 1 1 0 Laminin Domain II DUF4238 PF14022.1 XP_011277312.1 - 0.11 11.7 0.6 0.13 11.5 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4238) Spc7 PF08317.6 XP_011277312.1 - 0.11 11.0 6.4 0.12 11.0 4.4 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF2748 PF10871.3 XP_011277312.1 - 0.11 10.8 0.1 0.12 10.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2748) Peptidase_M13_N PF05649.8 XP_011277312.1 - 0.14 11.1 2.2 0.14 11.1 1.5 1.1 1 0 0 1 1 1 0 Peptidase family M13 DUF1759 PF03564.10 XP_011277312.1 - 0.14 11.9 1.6 0.28 10.9 1.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1759) SNARE PF05739.14 XP_011277312.1 - 0.14 11.8 2.7 1.2 8.9 0.2 2.4 1 1 1 2 2 2 0 SNARE domain Cir_Bir_Yir PF06022.6 XP_011277312.1 - 0.14 11.3 1.8 0.14 11.3 1.2 1.0 1 0 0 1 1 1 0 Plasmodium variant antigen protein Cir/Yir/Bir Nsp1_C PF05064.8 XP_011277312.1 - 0.15 11.7 3.9 0.18 11.4 0.6 1.9 1 1 0 1 1 1 0 Nsp1-like C-terminal region EspA PF03433.8 XP_011277312.1 - 0.16 11.4 2.5 0.17 11.3 1.8 1.0 1 0 0 1 1 1 0 EspA-like secreted protein Baculo_PEP_C PF04513.7 XP_011277312.1 - 0.16 11.8 0.9 0.2 11.4 0.6 1.3 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 XP_011277312.1 - 0.17 11.0 0.3 0.19 10.8 0.2 1.0 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF2935 PF11155.3 XP_011277312.1 - 0.18 11.9 1.3 0.22 11.5 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) Flagellin_N PF00669.15 XP_011277312.1 - 0.19 11.5 2.0 0.22 11.3 1.4 1.2 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region DUF972 PF06156.8 XP_011277312.1 - 0.19 12.0 5.5 0.23 11.8 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF2884 PF11101.3 XP_011277312.1 - 0.2 11.0 4.5 0.22 10.8 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) TMF_DNA_bd PF12329.3 XP_011277312.1 - 0.22 11.3 13.7 0.32 10.8 4.5 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Cep57_MT_bd PF06657.8 XP_011277312.1 - 0.22 11.4 5.5 0.22 11.4 0.9 2.3 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 tRNA-synt_His PF13393.1 XP_011277312.1 - 0.22 10.5 2.2 0.24 10.3 1.5 1.0 1 0 0 1 1 1 0 Histidyl-tRNA synthetase Syntaxin-6_N PF09177.6 XP_011277312.1 - 0.23 11.8 2.8 0.45 10.9 1.4 1.7 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DUF4349 PF14257.1 XP_011277312.1 - 0.23 10.6 3.6 0.98 8.6 1.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4349) DUF4337 PF14235.1 XP_011277312.1 - 0.24 11.2 3.6 0.25 11.1 2.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Osmo_CC PF08946.5 XP_011277312.1 - 0.25 11.3 3.6 0.23 11.5 1.6 1.7 1 1 1 2 2 2 0 Osmosensory transporter coiled coil MobC PF05713.6 XP_011277312.1 - 0.29 11.1 1.6 4.3 7.3 0.2 2.2 1 1 1 2 2 2 0 Bacterial mobilisation protein (MobC) DUF2175 PF09943.4 XP_011277312.1 - 0.35 10.9 2.8 0.45 10.5 1.9 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) YvrJ PF12841.2 XP_011277312.1 - 0.36 10.1 2.4 0.75 9.1 0.3 2.4 2 1 0 2 2 2 0 YvrJ protein family Occludin_ELL PF07303.8 XP_011277312.1 - 0.38 11.5 4.9 2.1 9.1 3.4 1.9 1 1 0 1 1 1 0 Occludin homology domain DUF4446 PF14584.1 XP_011277312.1 - 0.38 10.5 2.9 0.67 9.7 2.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) VIT1 PF01988.14 XP_011277312.1 - 0.44 9.9 2.9 0.48 9.8 2.0 1.1 1 0 0 1 1 1 0 VIT family TBPIP PF07106.8 XP_011277312.1 - 0.45 10.0 7.9 0.54 9.7 5.5 1.1 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF2031 PF09592.5 XP_011277312.1 - 0.49 9.5 4.3 0.68 9.0 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) UPF0184 PF03670.8 XP_011277312.1 - 0.51 10.5 3.9 0.79 9.9 2.7 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0184) IncA PF04156.9 XP_011277312.1 - 0.58 9.7 9.0 0.72 9.4 6.2 1.2 1 0 0 1 1 1 0 IncA protein DUF342 PF03961.8 XP_011277312.1 - 0.61 8.4 7.6 0.66 8.3 5.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) UPF0449 PF15136.1 XP_011277312.1 - 0.66 10.2 5.7 0.34 11.1 1.1 1.9 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 bZIP_1 PF00170.16 XP_011277312.1 - 0.7 9.8 4.9 2.4 8.1 3.4 2.0 1 1 0 1 1 1 0 bZIP transcription factor DUF3552 PF12072.3 XP_011277312.1 - 0.79 8.8 9.2 0.83 8.8 6.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) HSCB_C PF07743.8 XP_011277312.1 - 0.8 10.1 8.1 3.7 8.0 1.2 2.2 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain APG6 PF04111.7 XP_011277312.1 - 0.93 8.4 9.7 1 8.3 6.8 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF327 PF03885.8 XP_011277312.1 - 0.98 9.2 6.4 0.37 10.6 1.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF327) Prefoldin PF02996.12 XP_011277312.1 - 1.2 8.8 6.7 0.76 9.4 1.2 2.0 1 1 0 2 2 2 0 Prefoldin subunit V_ATPase_I PF01496.14 XP_011277312.1 - 1.5 6.5 5.7 1.5 6.6 4.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc24 PF08286.6 XP_011277312.1 - 1.7 8.3 8.8 6.9 6.4 6.1 1.8 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Enkurin PF13864.1 XP_011277312.1 - 1.8 8.7 7.3 3.7 7.8 5.1 1.7 1 1 0 1 1 1 0 Calmodulin-binding DUF4404 PF14357.1 XP_011277312.1 - 1.9 8.9 7.2 5.8 7.4 0.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) Seryl_tRNA_N PF02403.17 XP_011277312.1 - 2.4 8.2 8.4 4.4 7.3 5.8 1.5 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain AAA_23 PF13476.1 XP_011277312.1 - 2.8 8.2 10.9 2.9 8.1 7.6 1.1 1 0 0 1 1 1 0 AAA domain Laps PF10169.4 XP_011277312.1 - 3.8 7.7 6.8 4.6 7.4 4.7 1.1 1 0 0 1 1 1 0 Learning-associated protein DivIC PF04977.10 XP_011277312.1 - 4.3 6.8 8.0 13 5.3 4.4 2.0 1 1 0 1 1 1 0 Septum formation initiator CCDC-167 PF15188.1 XP_011277312.1 - 5.7 6.9 8.9 18 5.3 6.0 1.8 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 XhlA PF10779.4 XP_011277312.1 - 7.8 6.4 8.4 69 3.4 5.5 2.2 1 1 0 1 1 1 0 Haemolysin XhlA Syja_N PF02383.13 XP_011277313.1 - 5e-63 212.7 2.6 9.4e-63 211.8 1.8 1.4 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 XP_011277313.1 - 2.3e-24 86.6 0.0 4.4e-24 85.7 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family BTB PF00651.26 XP_011277314.1 - 7.4e-19 67.7 2.2 1.5e-08 34.5 0.1 2.7 2 0 0 2 2 2 2 BTB/POZ domain Ank PF00023.25 XP_011277314.1 - 9e-09 34.7 0.1 2.3e-07 30.2 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.2 XP_011277314.1 - 1.4e-05 25.3 0.0 0.00013 22.1 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 XP_011277314.1 - 6.1e-05 23.1 0.0 0.00019 21.5 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 XP_011277314.1 - 0.00053 19.9 0.1 0.0034 17.4 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 XP_011277314.1 - 0.0017 18.8 0.0 0.017 15.5 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) TRAP_alpha PF03896.11 XP_011277315.1 - 0.026 13.5 0.1 0.7 8.8 0.0 2.3 2 1 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Hexapep PF00132.19 XP_011277316.1 - 5.3e-14 50.9 7.2 2.3e-11 42.6 3.5 3.1 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 XP_011277316.1 - 5.9e-10 38.5 3.3 5.9e-10 38.5 2.3 2.5 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase Mac PF12464.3 XP_011277316.1 - 8.5e-10 38.5 0.1 1.5e-09 37.6 0.1 1.4 1 0 0 1 1 1 1 Maltose acetyltransferase ABC_tran PF00005.22 XP_011277317.1 - 3.1e-27 95.5 0.1 5.9e-15 55.7 0.0 3.2 3 1 0 3 3 3 2 ABC transporter SbcCD_C PF13558.1 XP_011277317.1 - 0.00012 21.9 0.1 0.011 15.5 0.0 2.3 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.1 XP_011277317.1 - 0.0017 18.4 14.0 0.017 15.0 0.0 3.7 3 1 0 4 4 4 2 AAA domain AAA_29 PF13555.1 XP_011277317.1 - 0.0045 16.4 0.0 0.0097 15.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 XP_011277317.1 - 0.0056 16.8 2.0 2.6 8.1 0.3 3.8 3 1 0 3 3 3 1 AAA domain AAA_23 PF13476.1 XP_011277317.1 - 0.032 14.5 5.9 0.91 9.8 0.1 2.6 3 0 0 3 3 3 0 AAA domain Miro PF08477.8 XP_011277317.1 - 0.071 13.6 0.0 0.26 11.8 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein AAA_16 PF13191.1 XP_011277317.1 - 0.15 11.9 0.3 0.61 10.0 0.0 2.2 2 2 0 2 2 2 0 AAA ATPase domain OCD_Mu_crystall PF02423.10 XP_011277318.1 - 9.3e-17 60.7 0.0 1.1e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Ribosomal_S15 PF00312.17 XP_011277319.1 - 2.1e-23 81.8 0.1 4.3e-23 80.8 0.1 1.5 2 0 0 2 2 2 1 Ribosomal protein S15 Ribosomal_S13_N PF08069.7 XP_011277319.1 - 5.9e-19 67.6 0.1 1.3e-18 66.5 0.0 1.6 2 0 0 2 2 2 1 Ribosomal S13/S15 N-terminal domain efb-c PF12199.3 XP_011277321.1 - 0.00012 21.8 0.2 0.4 10.5 0.0 2.8 2 0 0 2 2 2 2 Extracellular fibrinogen binding protein C terminal RPAP2_Rtr1 PF04181.8 XP_011277322.1 - 4.8e-19 68.2 3.7 9.6e-19 67.2 2.6 1.5 1 0 0 1 1 1 1 Rtr1/RPAP2 family DUF1759 PF03564.10 XP_011277322.1 - 0.00024 20.9 0.8 0.00045 20.0 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1759) DUF87 PF01935.12 XP_011277322.1 - 0.023 14.5 1.5 0.038 13.8 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF87 DUF3461 PF11944.3 XP_011277322.1 - 0.027 14.3 0.4 0.053 13.3 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3461) DUF747 PF05346.6 XP_011277323.1 - 1e-95 320.6 22.5 1e-95 320.6 15.6 1.5 1 1 1 2 2 2 1 Eukaryotic membrane protein family YMF19 PF02326.10 XP_011277323.1 - 0.015 15.8 1.1 0.015 15.8 0.8 4.3 5 1 0 5 5 5 0 Plant ATP synthase F0 COX15-CtaA PF02628.10 XP_011277324.1 - 1.8e-103 345.5 0.6 2.1e-103 345.3 0.4 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein 7TMR-DISM_7TM PF07695.6 XP_011277324.1 - 0.041 13.5 8.0 0.03 14.0 0.8 3.0 3 0 0 3 3 3 0 7TM diverse intracellular signalling UAF_Rrn10 PF05234.6 XP_011277325.1 - 0.00028 20.8 0.1 0.00068 19.6 0.0 1.6 1 1 0 1 1 1 1 UAF complex subunit Rrn10 adh_short PF00106.20 XP_011277326.1 - 1.2e-09 38.2 0.0 2e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 XP_011277326.1 - 0.00013 21.7 0.0 0.0003 20.5 0.0 1.6 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 XP_011277326.1 - 0.00018 21.3 0.0 0.00022 21.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Nol1_Nop2_Fmu PF01189.12 XP_011277327.1 - 1.8e-53 181.7 0.0 3.9e-36 124.8 0.0 2.2 2 0 0 2 2 2 2 NOL1/NOP2/sun family FtsJ PF01728.14 XP_011277327.1 - 0.00022 21.2 0.1 0.00073 19.5 0.0 1.9 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 XP_011277327.1 - 0.00049 20.6 0.0 0.0011 19.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 XP_011277327.1 - 0.013 15.5 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DGF-1_5 PF11038.3 XP_011277327.1 - 0.02 14.0 0.0 0.031 13.4 0.0 1.1 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi region 5 Nitr_red_alph_N PF14710.1 XP_011277327.1 - 0.11 12.7 1.5 0.35 11.1 1.0 1.8 1 0 0 1 1 1 0 Respiratory nitrate reductase alpha N-terminal TauD PF02668.11 XP_011277328.1 - 1.4e-39 136.3 0.0 2.1e-39 135.7 0.0 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family bZIP_2 PF07716.10 XP_011277329.1 - 1.6e-08 34.2 13.5 1.6e-08 34.2 9.4 2.3 2 1 0 2 2 2 1 Basic region leucine zipper DUF972 PF06156.8 XP_011277329.1 - 0.21 11.9 12.5 4.6 7.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF972) T2SG PF08334.6 XP_011277329.1 - 0.33 10.7 2.5 0.39 10.4 0.4 2.1 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein G TSC22 PF01166.13 XP_011277329.1 - 1.1 9.2 11.9 0.19 11.6 4.4 2.5 2 1 0 2 2 2 0 TSC-22/dip/bun family TBPIP PF07106.8 XP_011277329.1 - 4.5 6.7 24.6 0.11 12.0 11.2 2.0 1 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) zf-UBR PF02207.15 XP_011277330.1 - 2.8e-15 55.8 12.8 2.8e-15 55.8 8.9 3.3 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) Cas_Csa5 PF09702.5 XP_011277330.1 - 0.038 14.0 0.8 0.46 10.5 0.1 2.5 3 0 0 3 3 3 0 CRISPR-associated protein (Cas_Csa5) Thg1 PF04446.7 XP_011277331.1 - 2.7e-43 146.8 0.1 3.9e-43 146.3 0.1 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.1 XP_011277331.1 - 5e-39 132.7 0.3 8e-39 132.0 0.2 1.3 1 0 0 1 1 1 1 Thg1 C terminal domain Zea_mays_MuDR PF05928.6 XP_011277332.1 - 0.056 12.8 2.4 0.094 12.1 1.7 1.4 1 0 0 1 1 1 0 Zea mays MURB-like protein (MuDR) WD40 PF00400.27 XP_011277333.1 - 3e-12 45.9 9.4 1.9e-07 30.6 0.3 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 XP_011277333.1 - 3.2e-07 28.9 0.3 7.5e-07 27.7 0.2 1.5 1 1 0 1 1 1 1 Cytochrome D1 heme domain EMP24_GP25L PF01105.19 XP_011277334.1 - 5.4e-50 169.6 0.8 6.1e-50 169.4 0.5 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD LMBR1 PF04791.11 XP_011277334.1 - 0.042 12.4 0.3 0.072 11.6 0.2 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein PUF PF00806.14 XP_011277335.1 - 7.7e-54 176.2 40.2 2.3e-08 33.0 0.2 8.7 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat zf-RING_2 PF13639.1 XP_011277337.1 - 1.1e-10 41.1 6.7 6.1e-10 38.7 2.0 2.2 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 XP_011277337.1 - 2.3e-07 30.7 6.3 9e-06 25.7 1.6 2.3 1 1 1 2 2 2 2 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 XP_011277337.1 - 2.7e-06 27.3 8.0 8.2e-06 25.7 1.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 XP_011277337.1 - 2.7e-06 26.9 4.2 1.4e-05 24.6 0.6 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 XP_011277337.1 - 6.8e-06 25.6 4.7 1.7e-05 24.4 0.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 XP_011277337.1 - 4.7e-05 22.9 1.8 4.7e-05 22.9 1.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 XP_011277337.1 - 7.4e-05 22.3 2.9 9.1e-05 22.1 0.5 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 XP_011277337.1 - 0.00057 19.6 2.8 0.00057 19.6 1.9 1.8 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 XP_011277337.1 - 0.0011 18.8 1.7 0.0088 15.8 0.4 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger U-box PF04564.10 XP_011277337.1 - 0.0066 16.3 0.0 0.092 12.7 0.0 2.5 2 0 0 2 2 2 1 U-box domain Prok-RING_4 PF14447.1 XP_011277337.1 - 0.01 15.3 0.7 0.023 14.2 0.5 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 FANCL_C PF11793.3 XP_011277337.1 - 0.028 14.3 4.1 0.33 10.9 0.8 3.0 2 1 0 2 2 2 0 FANCL C-terminal domain zf-RING_4 PF14570.1 XP_011277337.1 - 0.03 13.9 3.2 0.19 11.3 0.4 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Cys_rich_CPCC PF14206.1 XP_011277337.1 - 0.094 12.2 0.6 0.52 9.9 0.1 2.3 2 0 0 2 2 2 0 Cysteine-rich CPCC zf-Nse PF11789.3 XP_011277337.1 - 0.22 11.0 3.4 0.18 11.3 1.1 1.8 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit DUF4640 PF15480.1 XP_011277337.1 - 1.1 8.7 9.2 0.097 12.2 0.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4640) CSTF2_hinge PF14327.1 XP_011277338.1 - 9.5e-18 64.0 5.9 9.5e-18 64.0 4.1 2.4 2 1 1 3 3 3 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 XP_011277338.1 - 4.7e-12 45.3 0.0 1.1e-11 44.2 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 XP_011277338.1 - 3.7e-11 42.8 0.0 8.1e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 XP_011277338.1 - 9.7e-06 25.3 0.0 1.8e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 XP_011277338.1 - 0.00031 19.9 0.8 0.00099 18.3 0.1 2.3 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal YLP PF02757.12 XP_011277338.1 - 0.0016 17.8 2.0 2.3 8.2 0.1 3.9 2 0 0 2 2 2 2 YLP motif Spo7_2_N PF15407.1 XP_011277338.1 - 0.037 13.4 0.0 0.11 12.0 0.0 1.8 1 0 0 1 1 1 0 Sporulation protein family 7 CSTF2_hinge PF14327.1 XP_011277339.1 - 3e-15 56.0 0.2 3e-15 56.0 0.1 1.9 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 XP_011277339.1 - 1.1e-10 41.0 0.1 2.8e-10 39.6 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 XP_011277339.1 - 9.4e-09 34.9 0.0 2.1e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 XP_011277339.1 - 1.2e-07 31.6 0.0 5.8e-07 29.4 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 XP_011277339.1 - 0.00041 19.5 2.6 0.00041 19.5 1.8 2.1 2 1 0 2 2 2 1 Transcription termination and cleavage factor C-terminal DUF1395 PF07160.7 XP_011277339.1 - 0.034 13.6 4.4 0.049 13.1 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1395) TFIIS_M PF07500.9 XP_011277340.1 - 1.7e-28 98.9 1.0 2.8e-28 98.2 0.7 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 XP_011277340.1 - 4.5e-18 64.6 6.4 7.1e-18 63.9 4.4 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Elf1 PF05129.8 XP_011277340.1 - 0.064 12.9 3.6 0.14 11.8 2.5 1.6 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like AKAP7_RIRII_bdg PF10470.4 XP_011277340.1 - 0.087 12.6 4.2 0.055 13.2 1.3 1.9 2 0 0 2 2 2 0 PKA-RI-RII subunit binding domain of A-kinase anchor protein Gly_radical PF01228.16 XP_011277340.1 - 0.44 10.9 3.7 0.26 11.6 0.3 2.1 1 1 2 3 3 3 0 Glycine radical Baculo_LEF5_C PF11792.3 XP_011277340.1 - 0.45 9.9 2.1 1.1 8.6 1.5 1.7 1 1 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain LicD PF04991.8 XP_011277340.1 - 0.48 10.5 3.5 0.22 11.5 0.6 1.7 1 1 1 2 2 2 0 LicD family Zn_Tnp_IS1595 PF12760.2 XP_011277340.1 - 0.95 9.3 5.5 7.3 6.4 4.1 2.0 1 1 1 2 2 2 0 Transposase zinc-ribbon domain Ribosomal_S27 PF01599.14 XP_011277340.1 - 0.97 9.3 6.2 2 8.3 0.2 2.8 3 0 0 3 3 3 0 Ribosomal protein S27a PALP PF00291.20 XP_011277343.1 - 3.2e-61 207.2 0.0 4.1e-61 206.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 XP_011277343.1 - 1.5e-15 56.7 0.1 4.7e-09 35.9 0.0 2.8 3 0 0 3 3 3 2 CBS domain GAD PF02938.9 XP_011277343.1 - 0.036 14.2 1.3 26 5.0 0.1 3.7 3 0 0 3 3 3 0 GAD domain BRCT PF00533.21 XP_011277343.1 - 0.13 12.4 3.1 2.1 8.5 0.0 3.8 4 0 0 4 4 4 0 BRCA1 C Terminus (BRCT) domain DUF749 PF05370.6 XP_011277343.1 - 2 8.3 12.4 0.89 9.5 2.3 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF749) MFS_1 PF07690.11 XP_011277344.1 - 6.1e-38 130.4 21.6 6.1e-38 130.4 15.0 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily ESSS PF10183.4 XP_011277344.1 - 0.15 12.4 0.1 0.55 10.6 0.0 2.0 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Pox_A14 PF05767.7 XP_011277344.1 - 2.5 8.1 12.4 1.2 9.1 0.1 3.6 4 0 0 4 4 4 0 Poxvirus virion envelope protein A14 F-box PF00646.28 XP_011277347.1 - 0.0086 15.7 0.4 0.029 14.0 0.3 2.0 1 0 0 1 1 1 1 F-box domain HRDC PF00570.18 XP_011277348.1 - 0.025 14.2 0.0 0.06 13.0 0.0 1.6 1 0 0 1 1 1 0 HRDC domain F-box PF00646.28 XP_011277349.1 - 0.00039 19.9 0.2 0.0011 18.5 0.2 1.8 1 0 0 1 1 1 1 F-box domain PRANC PF09372.5 XP_011277349.1 - 0.0023 17.8 0.1 2.8 7.9 0.0 3.2 2 0 0 2 2 2 2 PRANC domain F-box-like PF12937.2 XP_011277349.1 - 0.014 15.0 0.1 0.036 13.7 0.1 1.7 1 0 0 1 1 1 0 F-box-like LRR_4 PF12799.2 XP_011277350.1 - 0.00045 19.7 22.1 0.039 13.5 0.1 7.5 6 3 1 7 7 7 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 XP_011277350.1 - 0.008 15.9 1.2 0.008 15.9 0.9 6.4 6 2 2 8 8 8 1 Leucine rich repeat LRR_7 PF13504.1 XP_011277350.1 - 0.051 13.7 8.3 24 5.7 0.0 7.4 9 1 0 9 9 9 0 Leucine rich repeat LRR_1 PF00560.28 XP_011277350.1 - 9.5 6.7 11.9 1.5e+02 3.0 0.0 6.8 7 0 0 7 7 7 0 Leucine Rich Repeat F-box PF00646.28 XP_011277351.1 - 0.00035 20.1 0.2 0.0013 18.3 0.2 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 XP_011277351.1 - 0.0054 16.4 0.2 0.012 15.3 0.1 1.6 1 0 0 1 1 1 1 F-box-like WD40 PF00400.27 XP_011277352.1 - 6.7e-09 35.2 9.5 8e-05 22.3 0.1 4.7 5 1 0 5 5 5 3 WD domain, G-beta repeat MRG PF05712.8 XP_011277353.1 - 6.4e-52 175.2 0.2 6.4e-52 175.2 0.2 1.4 2 0 0 2 2 2 1 MRG Tudor-knot PF11717.3 XP_011277353.1 - 4.2e-08 32.7 2.4 1.5e-07 31.0 1.6 2.0 1 1 0 1 1 1 1 RNA binding activity-knot of a chromodomain Pkinase PF00069.20 XP_011277354.1 - 7e-35 120.4 0.0 1.2e-34 119.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011277354.1 - 1.5e-11 43.9 0.0 2.3e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 XP_011277354.1 - 0.0013 18.5 1.9 0.71 9.5 0.0 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family Lipase_GDSL_3 PF14606.1 XP_011277354.1 - 0.18 11.5 1.6 1.3 8.7 0.0 2.2 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family PAT1 PF09770.4 XP_011277354.1 - 0.19 9.9 22.7 0.25 9.5 15.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DDRGK PF09756.4 XP_011277354.1 - 2.2 7.6 10.5 4.5 6.6 7.3 1.4 1 0 0 1 1 1 0 DDRGK domain Cys_Met_Meta_PP PF01053.15 XP_011277355.1 - 2.3e-129 431.0 0.0 2.7e-129 430.8 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 XP_011277355.1 - 0.0022 17.0 0.0 0.0039 16.1 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II PIR PF00399.14 XP_011277356.1 - 6.2e-08 31.7 6.7 2.7e-07 29.6 4.6 2.2 1 0 0 1 1 1 1 Yeast PIR protein repeat TPR_11 PF13414.1 XP_011277357.1 - 7.5e-42 140.8 18.7 3.6e-15 55.3 0.0 6.5 4 2 3 7 7 7 7 TPR repeat TPR_2 PF07719.12 XP_011277357.1 - 1.7e-29 99.3 23.3 8.2e-05 22.2 0.2 10.7 9 2 2 11 11 10 7 Tetratricopeptide repeat TPR_1 PF00515.23 XP_011277357.1 - 1.3e-25 87.9 22.8 8.8e-05 21.9 0.4 10.7 10 1 1 11 11 11 7 Tetratricopeptide repeat TPR_16 PF13432.1 XP_011277357.1 - 8.3e-19 67.7 0.0 0.0035 17.9 0.0 5.0 4 1 0 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.1 XP_011277357.1 - 5e-17 61.6 8.1 0.00017 21.4 0.4 6.8 4 2 3 7 7 7 5 Tetratricopeptide repeat TPR_19 PF14559.1 XP_011277357.1 - 3.6e-16 59.2 9.2 6.6e-05 23.1 0.1 5.4 5 1 0 5 5 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 XP_011277357.1 - 2.1e-15 55.5 9.6 0.1 12.8 0.0 7.4 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 XP_011277357.1 - 2.1e-11 43.3 0.0 1.4 9.7 0.0 8.0 3 3 6 9 9 8 2 Tetratricopeptide repeat TPR_8 PF13181.1 XP_011277357.1 - 3.6e-11 41.9 29.8 0.0049 16.5 0.2 10.8 8 1 3 11 11 11 2 Tetratricopeptide repeat TPR_7 PF13176.1 XP_011277357.1 - 7e-08 31.7 11.7 1.4 8.9 0.0 8.2 9 0 0 9 9 9 2 Tetratricopeptide repeat Apc3 PF12895.2 XP_011277357.1 - 2.1e-06 27.7 19.0 0.0076 16.3 0.2 5.2 3 2 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.1 XP_011277357.1 - 0.00049 20.1 0.7 0.12 12.4 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 XP_011277357.1 - 0.0014 18.4 0.0 11 5.9 0.0 4.2 3 2 2 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 XP_011277357.1 - 0.026 14.9 14.8 2.3 8.8 0.1 7.1 9 0 0 9 9 7 0 Tetratricopeptide repeat DUF1771 PF08590.5 XP_011277357.1 - 0.15 12.0 1.7 3.1 7.8 0.0 3.2 3 1 0 3 3 2 0 Domain of unknown function (DUF1771) DUF3808 PF10300.4 XP_011277357.1 - 0.7 8.3 0.0 0.7 8.3 0.0 3.7 2 1 2 4 4 4 0 Protein of unknown function (DUF3808) PPR PF01535.15 XP_011277357.1 - 1.6 8.8 5.3 18 5.6 0.0 4.5 5 0 0 5 5 5 0 PPR repeat Pkinase PF00069.20 XP_011277358.1 - 7.7e-59 198.9 0.1 8.9e-59 198.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011277358.1 - 5.5e-27 94.4 0.0 7.7e-27 93.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 XP_011277358.1 - 0.00044 20.0 0.0 0.00084 19.1 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 XP_011277358.1 - 0.011 14.7 0.0 0.017 14.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 XP_011277358.1 - 0.017 14.2 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Apis_Csd PF11671.3 XP_011277358.1 - 1.9 8.2 8.3 0.15 11.8 2.3 1.7 2 0 0 2 2 2 0 Complementary sex determiner protein Ldh_1_N PF00056.18 XP_011277360.1 - 2.3e-44 150.6 0.2 3.5e-44 150.0 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 XP_011277360.1 - 5.9e-37 127.0 0.1 9.3e-37 126.4 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 XP_011277360.1 - 0.00016 20.5 0.0 0.00024 19.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.11 XP_011277360.1 - 0.038 13.3 0.3 0.5 9.6 0.1 2.2 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase Semialdhyde_dh PF01118.19 XP_011277360.1 - 0.051 13.8 0.1 0.17 12.2 0.0 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 XP_011277360.1 - 0.16 11.9 0.7 0.66 9.9 0.5 1.9 1 1 0 1 1 1 0 NADH(P)-binding Arf PF00025.16 XP_011277361.1 - 2.6e-32 111.4 2.2 2.9e-32 111.3 1.5 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 XP_011277361.1 - 1.7e-09 37.2 0.6 2e-09 36.9 0.4 1.0 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 XP_011277361.1 - 5.1e-07 28.7 6.1 1.3e-06 27.4 4.2 1.7 1 1 0 1 1 1 1 G-protein alpha subunit Ras PF00071.17 XP_011277361.1 - 2.7e-05 23.6 0.1 3.1e-05 23.3 0.1 1.1 1 0 0 1 1 1 1 Ras family GTP_EFTU PF00009.22 XP_011277361.1 - 0.0002 20.8 0.0 0.00024 20.5 0.0 1.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain cobW PF02492.14 XP_011277361.1 - 0.05 13.0 0.0 0.068 12.6 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.18 XP_011277361.1 - 0.053 13.4 0.0 0.087 12.7 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase DRMBL PF07522.9 XP_011277362.1 - 2.2e-18 66.2 0.9 5.3e-18 65.0 0.6 1.7 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 XP_011277362.1 - 1.7e-08 34.2 0.1 3.2e-08 33.3 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain STN PF07660.9 XP_011277362.1 - 0.012 15.1 0.2 0.041 13.4 0.1 2.0 2 0 0 2 2 2 0 Secretin and TonB N terminus short domain Lactamase_B PF00753.22 XP_011277362.1 - 0.037 13.6 0.1 0.12 12.0 0.1 1.7 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily GATA PF00320.22 XP_011277363.1 - 1.4e-14 53.1 1.4 2.6e-14 52.2 1.0 1.5 1 0 0 1 1 1 1 GATA zinc finger WH2 PF02205.15 XP_011277364.1 - 6.9e-12 44.5 1.7 9e-11 41.0 0.3 2.7 2 0 0 2 2 2 1 WH2 motif Evr1_Alr PF04777.8 XP_011277365.1 - 1.9e-29 101.3 3.1 2.8e-29 100.8 2.2 1.2 1 0 0 1 1 1 1 Erv1 / Alr family DUF3446 PF11928.3 XP_011277365.1 - 0.19 11.9 4.2 0.41 10.8 2.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) Asp PF00026.18 XP_011277366.1 - 1.4e-72 244.6 5.2 2.5e-72 243.7 3.6 1.4 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 XP_011277366.1 - 1.7e-08 34.5 0.0 4.5e-07 29.9 0.0 3.2 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 XP_011277366.1 - 0.00011 22.6 0.6 8 7.0 0.0 3.8 3 0 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.1 XP_011277366.1 - 0.0092 15.5 0.1 0.13 11.7 0.1 2.2 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal RVP PF00077.15 XP_011277366.1 - 0.01 15.7 0.1 3.7 7.5 0.0 2.9 2 0 0 2 2 2 0 Retroviral aspartyl protease PDZ_1 PF12812.2 XP_011277366.1 - 0.023 14.5 0.2 0.44 10.4 0.0 2.7 2 0 0 2 2 2 0 PDZ-like domain TC1 PF15063.1 XP_011277366.1 - 0.12 11.8 0.2 0.35 10.4 0.1 1.7 1 0 0 1 1 1 0 Thyroid cancer protein 1 Asp PF00026.18 XP_011277367.1 - 2.1e-69 234.1 18.9 1.5e-68 231.3 13.1 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 XP_011277367.1 - 0.0025 18.2 2.4 11 6.6 0.0 4.0 3 1 0 3 3 3 1 Aspartyl protease TAXi_C PF14541.1 XP_011277367.1 - 0.016 14.7 0.1 0.13 11.7 0.0 2.3 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 XP_011277367.1 - 0.12 12.1 0.8 4.1 7.2 0.0 3.0 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease Uso1_p115_C PF04871.8 XP_011277370.1 - 0.085 12.7 0.2 0.1 12.5 0.1 1.0 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region zf-C2H2 PF00096.21 XP_011277371.1 - 2.6e-07 30.5 8.6 0.0012 19.0 1.6 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 XP_011277371.1 - 6.2e-05 23.0 0.1 6.2e-05 23.0 0.0 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 XP_011277371.1 - 0.0014 18.8 11.0 0.012 15.8 1.2 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 XP_011277371.1 - 0.0025 17.9 1.2 0.0025 17.9 0.8 2.5 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 XP_011277371.1 - 0.018 15.1 0.7 0.018 15.1 0.5 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 XP_011277371.1 - 0.021 14.6 4.0 1.7 8.6 0.9 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger Acetyltransf_7 PF13508.1 XP_011277372.1 - 1.6e-07 31.3 0.0 6.5e-07 29.4 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 XP_011277372.1 - 1.7e-05 24.7 0.0 6.9e-05 22.8 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family DUF2433 PF10360.4 XP_011277373.1 - 4.5e-32 111.1 1.6 9.3e-32 110.1 1.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) MFS_1 PF07690.11 XP_011277374.1 - 1.2e-32 113.0 36.0 2.6e-19 69.1 10.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 XP_011277374.1 - 1.9e-11 43.2 37.0 2.8e-08 32.8 11.5 2.2 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 XP_011277374.1 - 1.9e-07 29.8 27.9 3.8e-07 28.8 18.8 2.0 1 1 0 1 1 1 1 MFS/sugar transport protein MFS_1_like PF12832.2 XP_011277374.1 - 0.00036 20.2 0.3 0.00036 20.2 0.2 2.5 2 0 0 2 2 2 1 MFS_1 like family ACOX PF01756.14 XP_011277375.1 - 2.9e-43 147.4 0.7 8e-43 145.9 0.2 1.9 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.14 XP_011277375.1 - 1.1e-17 63.3 0.4 1.9e-17 62.4 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.1 XP_011277375.1 - 4.9e-10 39.7 0.0 1e-09 38.7 0.0 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.19 XP_011277375.1 - 5.6e-09 36.2 0.0 3.1e-08 33.8 0.0 2.3 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain EB1 PF03271.12 XP_011277376.1 - 7e-14 51.6 0.4 1.7e-13 50.3 0.3 1.7 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 XP_011277376.1 - 7.1e-06 26.0 0.5 1.2e-05 25.3 0.3 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain Peptidase_M41 PF01434.13 XP_011277377.1 - 3.3e-75 252.2 0.0 4.8e-75 251.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 XP_011277377.1 - 1.1e-42 145.3 0.0 2.1e-42 144.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 XP_011277377.1 - 9.4e-07 28.9 0.2 2.3e-06 27.7 0.1 1.7 1 0 0 1 1 1 1 FtsH Extracellular AAA_17 PF13207.1 XP_011277377.1 - 0.00029 21.6 0.0 0.0015 19.3 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 XP_011277377.1 - 0.00059 19.9 0.1 0.16 12.1 0.1 2.5 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 XP_011277377.1 - 0.0019 17.0 0.0 0.0032 16.2 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_19 PF13245.1 XP_011277377.1 - 0.0044 16.7 0.7 0.012 15.2 0.5 1.7 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 XP_011277377.1 - 0.0051 15.8 0.0 0.011 14.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 XP_011277377.1 - 0.0085 15.8 0.1 0.034 13.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 XP_011277377.1 - 0.011 15.1 0.0 0.039 13.3 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein Zeta_toxin PF06414.7 XP_011277377.1 - 0.021 13.9 0.1 0.051 12.6 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin AAA_16 PF13191.1 XP_011277377.1 - 0.025 14.5 0.0 0.061 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.1 XP_011277377.1 - 0.03 14.6 0.7 0.22 11.8 0.0 2.7 3 0 0 3 3 2 0 AAA domain AAA_2 PF07724.9 XP_011277377.1 - 0.058 13.3 0.0 0.17 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_25 PF13481.1 XP_011277377.1 - 0.068 12.5 0.6 0.16 11.3 0.3 1.7 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 XP_011277377.1 - 0.12 12.2 0.1 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain CARD PF00619.16 XP_011277377.1 - 0.12 12.2 0.6 0.3 10.9 0.4 1.7 1 0 0 1 1 1 0 Caspase recruitment domain PRESAN PF09687.5 XP_011277377.1 - 0.29 11.1 0.1 0.29 11.1 0.1 2.4 2 0 0 2 2 2 0 Plasmodium RESA N-terminal GHMP_kinases_N PF00288.21 XP_011277378.1 - 7.7e-15 54.7 0.1 2e-14 53.4 0.1 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 XP_011277378.1 - 0.00024 21.2 0.0 0.00057 20.0 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal PG_binding_2 PF08823.6 XP_011277380.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative peptidoglycan binding domain DNA_pol_A_exo1 PF01612.15 XP_011277382.1 - 1.4e-05 24.6 0.0 3.2e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 3'-5' exonuclease Peptidase_S8 PF00082.17 XP_011277385.1 - 5.3e-46 157.0 1.4 7.8e-46 156.4 1.0 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 XP_011277385.1 - 7.6e-07 29.6 0.0 1.9e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Peptidase inhibitor I9 Microcin PF03526.8 XP_011277386.1 - 0.014 14.9 1.0 0.027 14.0 0.1 2.1 2 0 0 2 2 2 0 Colicin E1 (microcin) immunity protein Cyto_heme_lyase PF01265.12 XP_011277387.1 - 1e-88 297.2 1.5 2.4e-87 292.8 1.0 2.0 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase zf-Tim10_DDP PF02953.10 XP_011277388.1 - 6.8e-23 79.7 1.5 7.6e-23 79.5 1.0 1.0 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 XP_011277388.1 - 0.015 14.7 1.0 0.02 14.3 0.7 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Tom5 PF10642.4 XP_011277388.1 - 0.086 12.4 0.1 0.13 11.9 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase UDPGP PF01704.13 XP_011277389.1 - 9.5e-186 617.3 0.1 1.2e-185 617.0 0.1 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF4301 PF14134.1 XP_011277389.1 - 0.011 14.3 3.0 0.025 13.1 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4301) Copper-fist PF00649.13 XP_011277393.1 - 3.5e-05 22.9 1.9 3.5e-05 22.9 1.3 1.8 2 0 0 2 2 2 1 Copper fist DNA binding domain CENP-T PF15511.1 XP_011277393.1 - 5.7 6.0 40.7 9.7 5.3 28.2 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T ALIX_LYPXL_bnd PF13949.1 XP_011277394.1 - 0.074 12.0 0.2 0.21 10.5 0.0 1.7 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV GATase_5 PF13507.1 XP_011277395.1 - 4.6e-102 340.3 0.0 6.6e-102 339.8 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 XP_011277395.1 - 6.7e-47 159.3 0.6 4.5e-27 94.9 0.1 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 XP_011277395.1 - 4.8e-25 87.6 0.1 2.4e-24 85.3 0.0 2.3 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain DUF2462 PF09495.5 XP_011277396.1 - 1.3e-16 61.1 8.3 1.3e-16 61.1 5.7 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF2462) 60KD_IMP PF02096.15 XP_011277397.1 - 3.2e-25 88.9 6.4 1.2e-19 70.7 0.8 2.1 2 0 0 2 2 2 2 60Kd inner membrane protein Spt4 PF06093.8 XP_011277398.1 - 4.8e-18 64.8 0.0 6.5e-18 64.3 0.0 1.2 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger 2-Hacid_dh_C PF02826.14 XP_011277400.1 - 5.8e-40 136.3 0.0 2.2e-39 134.4 0.0 1.8 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 XP_011277400.1 - 9.9e-08 31.5 0.0 2.3e-07 30.3 0.0 1.7 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 XP_011277400.1 - 6.7e-06 26.0 0.0 1.1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ThiF PF00899.16 XP_011277400.1 - 0.0054 16.5 0.6 0.43 10.3 0.9 2.3 1 1 1 2 2 2 1 ThiF family AdoHcyase_NAD PF00670.16 XP_011277400.1 - 0.011 15.6 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.7 XP_011277400.1 - 0.028 13.8 0.0 0.047 13.0 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Rossmann-like PF10727.4 XP_011277400.1 - 0.056 13.1 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Rossmann-like domain GFO_IDH_MocA PF01408.17 XP_011277400.1 - 0.15 12.5 0.0 0.39 11.2 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Pkinase PF00069.20 XP_011277401.1 - 3.6e-33 114.8 0.0 4.4e-33 114.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011277401.1 - 4.7e-17 61.9 0.0 6.9e-17 61.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 XP_011277401.1 - 6.4e-08 31.8 0.0 8.1e-08 31.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 XP_011277401.1 - 0.0081 15.5 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 XP_011277401.1 - 0.042 13.5 0.1 0.06 13.0 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Methyltransf_31 PF13847.1 XP_011277402.1 - 2.5e-14 53.1 0.0 3.5e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 XP_011277402.1 - 1.9e-13 50.1 0.0 2.6e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 XP_011277402.1 - 8.1e-12 45.2 0.0 1.2e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 XP_011277402.1 - 1.5e-08 35.1 0.0 2.5e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 XP_011277402.1 - 4e-06 26.1 0.0 6.5e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 XP_011277402.1 - 2.1e-05 24.8 0.0 3.7e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 XP_011277402.1 - 0.0004 20.0 0.0 0.00069 19.2 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_10 PF05971.7 XP_011277402.1 - 0.00076 18.7 0.0 0.0012 18.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF890) N6_Mtase PF02384.11 XP_011277402.1 - 0.0011 18.0 0.0 0.002 17.2 0.0 1.4 1 0 0 1 1 1 1 N-6 DNA Methylase PrmA PF06325.8 XP_011277402.1 - 0.0031 16.6 0.0 0.0052 15.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.7 XP_011277402.1 - 0.0046 17.4 0.0 0.0076 16.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 XP_011277402.1 - 0.0054 17.1 0.0 0.011 16.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 XP_011277402.1 - 0.015 14.8 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.10 XP_011277402.1 - 0.13 11.6 0.0 0.29 10.4 0.0 1.5 1 1 0 1 1 1 0 Conserved hypothetical protein 95 Gcd10p PF04189.8 XP_011277403.1 - 1.3e-90 303.6 0.7 2e-90 302.9 0.5 1.3 1 0 0 1 1 1 1 Gcd10p family Sterile PF03015.14 XP_011277403.1 - 0.027 14.7 0.2 0.077 13.2 0.2 1.7 1 0 0 1 1 1 0 Male sterility protein PIN_4 PF13638.1 XP_011277403.1 - 0.04 14.0 0.7 1 9.4 0.0 2.3 2 0 0 2 2 2 0 PIN domain Foie-gras_1 PF11817.3 XP_011277403.1 - 0.047 13.1 0.2 0.081 12.3 0.2 1.3 1 0 0 1 1 1 0 Foie gras liver health family 1 Nol1_Nop2_Fmu PF01189.12 XP_011277404.1 - 5.8e-103 344.1 0.0 1.1e-102 343.2 0.0 1.5 1 0 0 1 1 1 1 NOL1/NOP2/sun family FtsJ PF01728.14 XP_011277404.1 - 0.008 16.1 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.1 XP_011277404.1 - 0.0095 15.5 0.0 0.025 14.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Actin PF00022.14 XP_011277405.1 - 8.2e-46 156.1 0.1 9.7e-29 99.9 0.0 2.8 2 2 0 2 2 2 2 Actin CAP_N PF01213.14 XP_011277406.1 - 1.1e-86 291.0 11.9 1.9e-86 290.1 8.3 1.4 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 XP_011277406.1 - 1.1e-55 187.2 4.9 1.9e-55 186.5 3.4 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 XP_011277406.1 - 0.098 12.0 0.8 16 4.9 0.1 2.6 2 1 1 3 3 3 0 Tubulin binding cofactor C Drf_GBD PF06371.8 XP_011277406.1 - 0.64 9.3 3.5 0.17 11.2 0.2 1.7 2 0 0 2 2 2 0 Diaphanous GTPase-binding Domain S4 PF01479.20 XP_011277407.1 - 1.6e-15 56.2 0.0 2.9e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 XP_011277407.1 - 0.00036 20.0 0.3 0.0012 18.4 0.0 1.9 2 0 0 2 2 2 1 S4 domain Eaf7 PF07904.8 XP_011277408.1 - 5.5e-11 42.2 0.6 5.5e-11 42.2 0.4 2.6 3 0 0 3 3 3 1 Chromatin modification-related protein EAF7 FKBP_C PF00254.23 XP_011277409.1 - 5.8e-31 106.3 0.0 8e-31 105.9 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Gryzun PF07919.7 XP_011277410.1 - 2.1e-36 125.4 20.3 2.1e-36 125.4 14.1 2.1 2 1 1 3 3 3 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.3 XP_011277410.1 - 8.9e-16 58.1 0.1 3.2e-12 46.4 0.1 2.3 1 1 0 1 1 1 1 Foie gras liver health family 1 Gryzun-like PF12742.2 XP_011277410.1 - 3.4e-07 29.9 0.2 1.3e-06 28.1 0.1 2.1 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking TRAPPC10 PF12584.3 XP_011277410.1 - 0.0003 20.2 0.0 0.00066 19.1 0.0 1.5 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 TPR_11 PF13414.1 XP_011277410.1 - 0.0015 18.1 3.0 0.0052 16.4 0.1 2.8 3 0 0 3 3 3 1 TPR repeat TPR_12 PF13424.1 XP_011277410.1 - 0.093 12.6 0.2 0.68 9.9 0.0 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 XP_011277410.1 - 1.1 9.2 3.7 5.7 7.1 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 XP_011277410.1 - 2.3 7.9 5.1 12 5.7 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat ECH PF00378.15 XP_011277411.1 - 2.6e-70 236.3 0.1 3e-70 236.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 XP_011277411.1 - 0.0012 18.5 0.0 0.0092 15.7 0.0 2.2 2 0 0 2 2 2 1 Peptidase family S49 UPF0180 PF03698.8 XP_011277411.1 - 0.06 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0180) Cullin PF00888.17 XP_011277412.1 - 1.4e-115 387.1 39.6 2.2e-115 386.4 27.4 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 XP_011277412.1 - 4.1e-28 97.0 2.4 4.1e-28 97.0 1.7 2.2 2 0 0 2 2 2 1 Cullin protein neddylation domain Mus7 PF09462.5 XP_011277414.1 - 2.2e-13 49.9 3.0 2.2e-13 49.9 2.1 2.5 1 1 0 2 2 2 2 Mus7/MMS22 family AIP3 PF03915.8 XP_011277415.1 - 2.5e-149 497.8 19.1 2.5e-149 497.8 13.2 2.0 2 0 0 2 2 2 1 Actin interacting protein 3 DUF4462 PF14692.1 XP_011277415.1 - 0.079 12.2 0.7 0.19 11.0 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) Telomerase_RBD PF12009.3 XP_011277416.1 - 1.3e-23 83.4 4.7 4e-23 81.8 3.3 1.9 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 XP_011277416.1 - 3.6e-11 42.8 2.8 6e-11 42.1 0.6 2.3 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) dCMP_cyt_deam_1 PF00383.17 XP_011277417.1 - 1.4e-09 37.5 0.6 2.2e-09 36.8 0.4 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 XP_011277417.1 - 0.066 13.0 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Bd3614-like deaminase Cnl2_NKP2 PF09447.5 XP_011277418.1 - 5.6e-11 41.9 0.1 1.5e-10 40.5 0.1 1.8 1 0 0 1 1 1 1 Cnl2/NKP2 family protein GcpE PF04551.9 XP_011277418.1 - 0.017 13.9 0.2 0.025 13.3 0.2 1.2 1 0 0 1 1 1 0 GcpE protein DUF947 PF06102.7 XP_011277418.1 - 0.02 14.7 4.2 0.034 13.9 2.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF947) Herpes_UL33 PF03581.8 XP_011277418.1 - 0.056 13.3 0.1 0.091 12.6 0.1 1.3 1 0 0 1 1 1 0 Herpesvirus UL33-like protein P4Ha_N PF08336.6 XP_011277418.1 - 0.38 10.5 4.4 0.29 10.9 0.4 2.1 1 1 1 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF948 PF06103.6 XP_011277418.1 - 1.3 8.9 5.2 3.2 7.6 3.6 1.9 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) SNF5 PF04855.7 XP_011277419.1 - 1.5e-62 211.2 5.4 1.2e-60 204.9 3.7 2.1 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 EF1_GNE PF00736.14 XP_011277420.1 - 1.3e-31 108.0 1.6 1.3e-31 108.0 1.1 1.8 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 XP_011277420.1 - 1.4e-14 53.9 5.8 1.4e-14 53.9 4.0 3.2 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region Cwf_Cwc_15 PF04889.7 XP_011277420.1 - 0.004 16.8 1.2 0.004 16.8 0.8 1.6 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein GST_C_3 PF14497.1 XP_011277420.1 - 0.022 15.2 0.0 0.052 14.0 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF3752 PF12572.3 XP_011277420.1 - 0.088 12.9 3.5 0.14 12.2 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) ExbD PF02472.11 XP_011277420.1 - 0.51 10.3 2.9 2.2 8.2 2.0 2.0 1 1 0 1 1 1 0 Biopolymer transport protein ExbD/TolR Fungal_trans_2 PF11951.3 XP_011277421.1 - 1.9e-24 85.9 0.4 3.3e-24 85.2 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF773 PF05600.7 XP_011277422.1 - 0.26 10.0 4.0 0.33 9.6 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF773) Anp1 PF03452.9 XP_011277423.1 - 4.5e-115 383.4 0.0 5.4e-115 383.1 0.0 1.0 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.21 XP_011277423.1 - 0.00088 18.9 0.0 0.0017 18.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 zf-CCCH PF00642.19 XP_011277424.1 - 4e-12 45.5 8.5 1.2e-05 24.8 1.8 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) NOGCT PF08155.6 XP_011277425.1 - 1.3e-27 95.2 1.9 3.4e-27 93.8 1.3 1.8 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.9 XP_011277425.1 - 3.9e-27 93.8 0.4 8.6e-27 92.7 0.3 1.6 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 XP_011277425.1 - 1.1e-15 57.5 0.0 2.6e-15 56.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 XP_011277425.1 - 5.7e-09 35.4 0.0 1.1e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 XP_011277425.1 - 0.012 16.0 0.0 0.032 14.7 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein Surf_Ag_VNR PF07244.10 XP_011277425.1 - 0.029 14.7 3.7 1 9.8 0.0 3.5 4 0 0 4 4 4 0 Surface antigen variable number repeat Dynamin_N PF00350.18 XP_011277425.1 - 0.055 13.2 2.5 7.9 6.2 0.0 3.1 2 2 1 3 3 3 0 Dynamin family AAA_23 PF13476.1 XP_011277425.1 - 0.48 10.7 7.8 5.8 7.1 0.0 2.7 2 1 0 2 2 2 0 AAA domain TauD PF02668.11 XP_011277426.1 - 3.9e-50 170.9 0.0 5.8e-50 170.3 0.0 1.3 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.1 XP_011277426.1 - 0.0011 19.4 0.1 0.26 11.8 0.0 2.6 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily Voltage_CLC PF00654.15 XP_011277427.1 - 6.6e-86 288.5 21.0 6.6e-86 288.5 14.5 1.9 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 XP_011277427.1 - 9.1e-09 34.9 0.1 8.1e-06 25.5 0.0 2.5 2 0 0 2 2 2 2 CBS domain APC_crr PF05923.7 XP_011277427.1 - 0.036 13.6 0.0 0.036 13.6 0.0 2.0 2 0 0 2 2 2 0 APC cysteine-rich region NDUF_B5 PF09781.4 XP_011277427.1 - 0.058 12.6 0.0 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit ATPase_gene1 PF09527.5 XP_011277427.1 - 1.9 8.3 8.7 2.7 7.8 0.1 3.5 3 0 0 3 3 3 0 Putative F0F1-ATPase subunit (ATPase_gene1) MSC PF09402.5 XP_011277428.1 - 0.21 10.2 0.0 0.21 10.2 0.0 2.4 3 0 0 3 3 3 0 Man1-Src1p-C-terminal domain PRD PF00874.15 XP_011277428.1 - 1.7 8.7 8.2 0.24 11.5 0.3 3.4 3 0 0 3 3 3 0 PRD domain Not3 PF04065.10 XP_011277429.1 - 1.2e-64 217.8 31.3 1.2e-64 217.8 21.7 1.8 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 XP_011277429.1 - 9.1e-12 45.0 0.5 9.1e-12 45.0 0.3 2.2 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family DUF3348 PF11828.3 XP_011277429.1 - 0.028 13.8 0.9 0.054 12.9 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3348) bZIP_1 PF00170.16 XP_011277430.1 - 5.7e-09 35.7 8.1 5.7e-09 35.7 5.6 2.1 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 XP_011277430.1 - 5.4e-06 26.1 6.8 5.4e-06 26.1 4.7 2.1 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 XP_011277430.1 - 0.017 15.4 4.3 0.017 15.4 3.0 3.4 4 0 0 4 4 4 0 bZIP Maf transcription factor YbaB_DNA_bd PF02575.11 XP_011277430.1 - 0.27 11.1 0.0 0.27 11.1 0.0 2.5 2 1 1 3 3 3 0 YbaB/EbfC DNA-binding family Peptidase_S46 PF10459.4 XP_011277431.1 - 0.036 12.4 1.0 0.053 11.9 0.7 1.1 1 0 0 1 1 1 0 Peptidase S46 Pkinase PF00069.20 XP_011277432.1 - 4.3e-59 199.7 0.1 5.1e-59 199.5 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011277432.1 - 8.4e-23 80.7 0.0 1.2e-22 80.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 XP_011277432.1 - 1.7e-07 31.2 0.0 2.1e-05 24.3 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 XP_011277432.1 - 0.006 16.1 0.6 0.014 14.9 0.0 1.9 2 0 0 2 2 2 1 Choline/ethanolamine kinase Kdo PF06293.9 XP_011277432.1 - 0.035 13.1 0.1 0.071 12.1 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC1 PF03109.11 XP_011277432.1 - 0.052 13.5 0.1 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 ABC1 family YrbL-PhoP_reg PF10707.4 XP_011277432.1 - 0.061 12.6 0.2 1.2 8.3 0.0 2.3 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL YlzJ PF14035.1 XP_011277432.1 - 0.1 12.6 0.5 6.8 6.8 0.2 2.4 2 0 0 2 2 2 0 YlzJ-like protein F_actin_cap_B PF01115.12 XP_011277433.1 - 4e-98 327.4 1.3 4.9e-98 327.1 0.9 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Erg28 PF03694.8 XP_011277434.1 - 1.3e-37 128.1 2.8 2.7e-37 127.1 2.0 1.5 1 1 0 1 1 1 1 Erg28 like protein Tmemb_18A PF09771.4 XP_011277434.1 - 0.05 13.5 0.2 0.065 13.2 0.1 1.3 1 0 0 1 1 1 0 Transmembrane protein 188 cNMP_binding PF00027.24 XP_011277435.1 - 8.3e-46 153.7 0.2 6e-22 77.2 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.12 XP_011277435.1 - 5.5e-10 38.4 1.9 1.4e-09 37.2 1.3 1.7 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Herpes_BLLF1 PF05109.8 XP_011277435.1 - 5.1 4.9 11.0 6.7 4.5 7.6 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) DUF605 PF04652.11 XP_011277435.1 - 9.4 5.5 17.1 12 5.1 11.8 1.2 1 0 0 1 1 1 0 Vta1 like DUF3020 PF11223.3 XP_011277436.1 - 3.5e-14 52.9 7.8 3.5e-14 52.9 5.4 5.5 5 0 0 5 5 5 1 Protein of unknown function (DUF3020) MFS_1 PF07690.11 XP_011277437.1 - 6.3e-07 28.4 25.2 1.9e-06 26.8 16.1 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Zip PF02535.17 XP_011277438.1 - 2.2e-58 197.7 9.1 3.1e-56 190.7 6.3 2.1 1 1 0 1 1 1 1 ZIP Zinc transporter SWIRM PF04433.12 XP_011277439.1 - 7.4e-34 115.7 0.5 2.5e-33 114.0 0.3 2.0 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 XP_011277439.1 - 9.5e-08 31.9 0.0 2.4e-07 30.6 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 XP_011277439.1 - 1.6e-07 31.3 0.1 6.3e-07 29.3 0.1 2.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF3653 PF12375.3 XP_011277439.1 - 0.15 12.3 0.2 0.3 11.3 0.2 1.5 1 0 0 1 1 1 0 Phage protein SNF2_N PF00176.18 XP_011277440.1 - 1e-70 237.9 2.4 1.5e-69 234.0 1.7 2.3 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 XP_011277440.1 - 1.1e-16 60.4 0.0 2.7e-16 59.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 XP_011277440.1 - 1.1e-05 25.0 0.0 4.5e-05 23.0 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase TipAS PF07739.8 XP_011277440.1 - 0.042 14.1 0.8 0.15 12.3 0.6 2.0 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain Toxin_7 PF05980.7 XP_011277441.1 - 0.0057 16.6 2.6 0.011 15.6 1.8 1.5 1 0 0 1 1 1 1 Toxin 7 DAO PF01266.19 XP_011277442.1 - 2.5e-43 148.3 0.0 2.9e-43 148.1 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 XP_011277442.1 - 5.9e-06 26.2 0.1 0.002 18.0 0.1 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 XP_011277442.1 - 1.8e-05 24.6 0.0 7.1e-05 22.7 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 XP_011277442.1 - 0.0058 15.7 0.0 0.014 14.5 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.11 XP_011277442.1 - 0.0061 16.0 0.0 0.12 11.7 0.0 2.3 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.22 XP_011277442.1 - 0.012 16.0 0.0 0.078 13.3 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 XP_011277442.1 - 0.031 13.1 0.0 0.046 12.5 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain UDPG_MGDP_dh_N PF03721.9 XP_011277442.1 - 0.06 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 XP_011277442.1 - 0.064 12.8 0.0 0.098 12.2 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 XP_011277442.1 - 0.1 11.4 0.0 2.2 7.0 0.0 2.4 3 0 0 3 3 3 0 Glucose inhibited division protein A TrkA_N PF02254.13 XP_011277442.1 - 0.1 12.5 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Thi4 PF01946.12 XP_011277442.1 - 0.13 11.3 0.0 0.24 10.4 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Phosducin PF02114.11 XP_011277444.1 - 9.2e-15 54.0 0.4 1.2e-14 53.7 0.3 1.2 1 0 0 1 1 1 1 Phosducin Mre11_DNA_bind PF04152.9 XP_011277445.1 - 4.2e-51 173.2 1.2 7.6e-51 172.4 0.0 2.1 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 XP_011277445.1 - 8.3e-26 90.6 1.9 1.7e-25 89.5 1.3 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 XP_011277445.1 - 0.00046 20.0 0.0 0.0011 18.8 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF4559 PF15112.1 XP_011277445.1 - 0.074 12.2 1.1 0.14 11.3 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) RNase_T PF00929.19 XP_011277447.1 - 4.4e-05 23.8 0.0 0.00017 21.8 0.0 1.7 2 0 0 2 2 2 1 Exonuclease CTNNBL PF08216.6 XP_011277447.1 - 0.038 13.5 0.1 0.049 13.2 0.0 1.1 1 0 0 1 1 1 0 Catenin-beta-like, Arm-motif containing nuclear MFS_1 PF07690.11 XP_011277449.1 - 1.3e-33 116.1 35.1 1.3e-33 116.1 24.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 XP_011277449.1 - 1.4e-05 23.4 5.5 1.4e-05 23.4 3.8 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) BPD_transp_2 PF02653.11 XP_011277450.1 - 0.099 11.5 0.3 0.11 11.3 0.2 1.1 1 0 0 1 1 1 0 Branched-chain amino acid transport system / permease component Rhodanese PF00581.15 XP_011277451.1 - 8.5e-16 58.3 0.0 3e-15 56.5 0.0 1.8 1 1 1 2 2 2 1 Rhodanese-like domain DUF947 PF06102.7 XP_011277452.1 - 3.9e-42 143.9 31.1 3.9e-42 143.9 21.6 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF947) MtlR PF05068.7 XP_011277452.1 - 0.016 14.6 0.5 0.027 13.8 0.4 1.3 1 0 0 1 1 1 0 Mannitol repressor Thioredoxin PF00085.15 XP_011277453.1 - 3.3e-26 90.9 2.5 6.2e-26 90.1 0.5 2.4 2 1 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.1 XP_011277453.1 - 6e-07 29.4 2.1 7.2e-05 22.8 0.1 3.7 3 1 1 4 4 4 1 Thioredoxin-like Thioredoxin_2 PF13098.1 XP_011277453.1 - 2.9e-06 27.4 0.3 1.1e-05 25.5 0.2 2.0 1 0 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 XP_011277453.1 - 9.7e-05 22.0 0.7 0.00042 19.9 0.2 2.2 2 1 0 2 2 2 1 AhpC/TSA family Thioredoxin_6 PF13848.1 XP_011277453.1 - 0.00041 20.1 2.4 0.00047 20.0 0.0 2.3 2 1 1 3 3 3 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 XP_011277453.1 - 0.005 16.8 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_4 PF13462.1 XP_011277453.1 - 0.03 14.3 2.1 0.043 13.8 0.2 2.1 2 0 0 2 2 2 0 Thioredoxin Peptidase_S49_N PF08496.5 XP_011277453.1 - 0.031 14.0 2.2 0.068 12.9 1.5 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DIM1 PF02966.11 XP_011277453.1 - 0.054 13.0 0.1 0.38 10.2 0.0 2.3 2 1 1 3 3 3 0 Mitosis protein DIM1 DSBA PF01323.15 XP_011277453.1 - 0.11 12.0 0.5 1.6 8.2 0.1 2.5 2 1 1 3 3 3 0 DSBA-like thioredoxin domain Thioredoxin_9 PF14595.1 XP_011277453.1 - 0.24 10.9 0.0 0.24 10.9 0.0 2.2 3 0 0 3 3 3 0 Thioredoxin PMSR PF01625.16 XP_011277454.1 - 1.4e-44 151.7 1.8 1.8e-44 151.3 1.2 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase AMMECR1 PF01871.12 XP_011277455.1 - 5.3e-38 129.8 0.0 6.2e-38 129.5 0.0 1.1 1 0 0 1 1 1 1 AMMECR1 SLBB PF10531.4 XP_011277455.1 - 0.12 12.3 0.1 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 SLBB domain Lum_binding PF00677.12 XP_011277456.1 - 3.2e-48 161.5 8.5 3.5e-25 87.7 0.2 2.2 2 0 0 2 2 2 2 Lumazine binding domain Gifsy-2 PF13856.1 XP_011277456.1 - 0.042 13.9 0.0 2.2 8.4 0.0 2.3 2 0 0 2 2 2 0 ATP-binding sugar transporter from pro-phage His_Phos_1 PF00300.17 XP_011277457.1 - 3e-29 102.1 0.0 3.8e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 XP_011277457.1 - 0.014 14.7 0.2 0.084 12.1 0.1 1.9 1 1 1 2 2 2 0 Histidine phosphatase superfamily (branch 2) DUF3091 PF11291.3 XP_011277457.1 - 0.07 13.0 0.4 0.19 11.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3091) Ion_trans_2 PF07885.11 XP_011277458.1 - 1.5e-31 107.9 36.1 7.9e-18 63.9 5.9 4.4 4 1 1 5 5 5 2 Ion channel DUF2231 PF09990.4 XP_011277458.1 - 0.08 13.2 6.7 1.4 9.2 0.1 3.6 3 1 0 3 3 3 0 Predicted membrane protein (DUF2231) Lig_chan PF00060.21 XP_011277458.1 - 0.62 9.7 12.2 1.1 8.9 2.3 4.1 2 1 1 3 3 3 0 Ligand-gated ion channel DUF4231 PF14015.1 XP_011277458.1 - 4.8 7.2 9.6 0.7 9.8 0.2 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) Agouti PF05039.7 XP_011277459.1 - 4.8 7.5 9.0 17 5.8 6.2 1.9 1 1 0 1 1 1 0 Agouti protein zf-RING_2 PF13639.1 XP_011277461.1 - 1e-07 31.6 4.2 1e-07 31.6 2.9 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 XP_011277461.1 - 1.7e-05 24.7 4.2 3.5e-05 23.7 2.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 XP_011277461.1 - 2.4e-05 23.9 1.7 5.2e-05 22.8 1.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 XP_011277461.1 - 7.7e-05 22.2 2.3 0.00018 21.1 1.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 XP_011277461.1 - 0.00094 18.7 3.4 0.0019 17.7 2.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FA_desaturase PF00487.19 XP_011277461.1 - 0.0034 16.8 0.1 0.0056 16.1 0.1 1.3 1 0 0 1 1 1 1 Fatty acid desaturase EI24 PF07264.6 XP_011277461.1 - 0.012 15.0 0.6 0.012 15.0 0.4 1.5 2 0 0 2 2 2 0 Etoposide-induced protein 2.4 (EI24) zf-rbx1 PF12678.2 XP_011277461.1 - 0.26 11.4 2.9 1.5 8.9 2.0 2.3 2 1 0 2 2 2 0 RING-H2 zinc finger DUF3671 PF12420.3 XP_011277461.1 - 4.6 7.2 9.8 2.4 8.2 0.9 2.7 1 1 1 2 2 2 0 Protein of unknown function DUF3139 PF11337.3 XP_011277461.1 - 5.2 7.4 7.6 16 5.8 0.3 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3139) Flocculin_t3 PF13928.1 XP_011277463.1 - 5.5e-11 42.4 26.2 5.5e-11 42.4 18.1 4.3 5 1 0 5 5 5 1 Flocculin type 3 repeat Trypan_PARP PF05887.6 XP_011277463.1 - 0.00081 19.2 33.1 0.00081 19.2 23.0 4.9 3 1 1 4 4 4 1 Procyclic acidic repetitive protein (PARP) zf-RING_2 PF13639.1 XP_011277464.1 - 5e-08 32.6 6.9 9e-08 31.8 4.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 XP_011277464.1 - 1.1e-06 28.2 3.1 2.4e-06 27.1 2.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 XP_011277464.1 - 8.4e-05 22.5 4.9 0.00018 21.4 3.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 XP_011277464.1 - 0.00019 21.0 3.4 0.00036 20.1 2.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 XP_011277464.1 - 0.00088 18.9 2.2 0.002 17.7 1.6 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.20 XP_011277464.1 - 0.0023 17.5 4.6 0.0056 16.3 3.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 XP_011277464.1 - 0.034 13.8 1.2 0.11 12.2 0.8 1.9 1 1 0 1 1 1 0 PHD-finger FANCL_C PF11793.3 XP_011277464.1 - 0.098 12.6 1.8 0.31 11.0 1.2 1.8 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.1 XP_011277464.1 - 0.14 11.7 1.7 0.35 10.4 1.2 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 XP_011277464.1 - 0.75 9.9 4.5 1.3 9.1 2.7 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger Alk_phosphatase PF00245.15 XP_011277465.1 - 6.1e-90 301.9 0.4 7.2e-90 301.6 0.3 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 XP_011277465.1 - 0.005 16.2 0.8 0.014 14.7 0.1 2.0 3 0 0 3 3 3 1 Metalloenzyme superfamily Sulfatase PF00884.18 XP_011277465.1 - 0.049 12.8 1.0 0.58 9.2 0.1 2.2 2 0 0 2 2 2 0 Sulfatase Peptidase_S8 PF00082.17 XP_011277466.1 - 4.3e-44 150.7 6.8 5.8e-44 150.3 4.7 1.2 1 0 0 1 1 1 1 Subtilase family MFS_1 PF07690.11 XP_011277467.1 - 4.5e-36 124.2 27.5 6.5e-36 123.7 17.6 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Vpu PF00558.14 XP_011277467.1 - 1.9 8.0 4.7 0.25 10.9 0.2 1.8 2 0 0 2 2 2 0 Vpu protein DUF4451 PF14616.1 XP_011277468.1 - 0.001 18.8 3.2 0.0031 17.2 2.2 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4451) Aldo_ket_red PF00248.16 XP_011277469.1 - 1.2e-61 207.9 0.0 1.4e-61 207.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.11 XP_011277470.1 - 1.7e-34 119.0 13.0 1.7e-34 119.0 9.0 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Arteri_Gl PF00951.13 XP_011277470.1 - 0.077 12.5 0.1 0.077 12.5 0.1 2.6 3 0 0 3 3 3 0 Arterivirus GL envelope glycoprotein COesterase PF00135.23 XP_011277471.1 - 3e-99 333.1 0.2 3.9e-99 332.7 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 XP_011277471.1 - 0.00012 21.6 0.1 0.00097 18.7 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 XP_011277471.1 - 0.011 14.9 0.1 0.028 13.6 0.1 1.6 1 1 0 1 1 1 0 Prolyl oligopeptidase family SLAC1 PF03595.12 XP_011277472.1 - 8.1e-27 93.7 8.6 9e-27 93.5 6.0 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF4282 PF14110.1 XP_011277472.1 - 0.18 12.0 0.0 0.18 12.0 0.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4282) SLAC1 PF03595.12 XP_011277473.1 - 1.9e-46 158.2 25.4 2.3e-46 158.0 17.6 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Translin PF01997.11 XP_011277473.1 - 0.097 12.2 0.1 0.13 11.8 0.1 1.2 1 0 0 1 1 1 0 Translin family COX14 PF14880.1 XP_011277473.1 - 0.21 11.2 2.4 12 5.6 0.1 2.8 2 0 0 2 2 2 0 Cytochrome oxidase c assembly Pyr_redox_2 PF07992.9 XP_011277474.1 - 9.1e-42 143.2 2.2 1.6e-41 142.4 1.5 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 XP_011277474.1 - 3.4e-36 123.6 0.3 2e-35 121.1 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 XP_011277474.1 - 1.2e-19 70.4 5.7 1.5e-19 70.1 0.3 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 XP_011277474.1 - 6e-11 42.7 0.3 6.9e-09 36.0 0.0 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 XP_011277474.1 - 6.8e-08 31.3 7.4 0.00072 18.1 0.0 3.5 2 1 1 4 4 4 2 HI0933-like protein FAD_oxidored PF12831.2 XP_011277474.1 - 3.9e-05 22.9 0.3 6.4e-05 22.2 0.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase K_oxygenase PF13434.1 XP_011277474.1 - 0.0004 19.3 0.0 0.00062 18.7 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.19 XP_011277474.1 - 0.0011 17.9 6.1 0.25 10.1 1.6 3.4 4 0 0 4 4 4 1 FAD binding domain AlaDh_PNT_C PF01262.16 XP_011277474.1 - 0.004 16.7 0.0 0.011 15.3 0.0 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 XP_011277474.1 - 0.0061 16.2 0.0 0.016 14.8 0.0 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 XP_011277474.1 - 0.017 14.2 2.4 0.35 9.9 0.0 2.7 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 XP_011277474.1 - 0.11 12.3 0.0 0.11 12.3 0.0 3.1 4 0 0 4 4 4 0 FAD-NAD(P)-binding DAO PF01266.19 XP_011277474.1 - 0.13 11.1 14.6 0.18 10.6 1.8 3.9 3 1 0 4 4 4 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 XP_011277474.1 - 0.34 10.9 8.0 0.11 12.5 2.4 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 XP_011277474.1 - 1.5 7.5 16.0 0.37 9.5 3.9 3.5 2 2 1 3 3 3 0 Glucose inhibited division protein A Ribosomal_S6e PF01092.14 XP_011277475.1 - 1.8e-61 205.4 0.4 2.9e-61 204.7 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S6e Cadherin_C PF01049.12 XP_011277475.1 - 0.065 13.2 0.2 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 Cadherin cytoplasmic region SRF-TF PF00319.13 XP_011277476.1 - 7e-08 31.5 0.0 1.2e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Prothymosin PF03247.9 XP_011277476.1 - 0.011 15.8 14.4 0.011 15.8 9.9 3.7 4 0 0 4 4 4 0 Prothymosin/parathymosin family Nop14 PF04147.7 XP_011277476.1 - 0.34 8.7 17.6 0.04 11.8 5.5 2.2 2 0 0 2 2 2 0 Nop14-like family PAT1 PF09770.4 XP_011277476.1 - 0.63 8.2 72.1 0.28 9.3 48.2 1.5 1 1 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1510 PF07423.6 XP_011277476.1 - 8.3 5.7 22.9 3.9 6.7 7.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) MBA1 PF07961.6 XP_011277477.1 - 1.1e-86 289.4 0.8 1.7e-86 288.9 0.5 1.2 1 0 0 1 1 1 1 MBA1-like protein Glyco_transf_20 PF00982.16 XP_011277477.1 - 0.068 11.6 1.4 0.11 10.9 1.0 1.4 1 1 0 1 1 1 0 Glycosyltransferase family 20 Sec16_C PF12931.2 XP_011277478.1 - 4.5e-50 170.9 1.5 9.8e-50 169.8 1.1 1.6 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Nup96 PF12110.3 XP_011277478.1 - 0.011 14.8 0.4 0.011 14.8 0.3 1.9 2 0 0 2 2 2 0 Nuclear protein 96 Radical_SAM PF04055.16 XP_011277479.1 - 3.1e-17 63.2 0.1 7.9e-17 61.9 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 XP_011277479.1 - 1.2e-11 44.4 0.1 4.2e-11 42.7 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 XP_011277479.1 - 0.11 12.6 0.1 0.29 11.3 0.1 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain TBX PF12598.3 XP_011277480.1 - 0.041 14.2 1.9 1.7 9.0 0.1 2.7 2 0 0 2 2 2 0 T-box transcription factor MFS_1 PF07690.11 XP_011277481.1 - 1.7e-28 99.3 24.8 1.9e-28 99.1 16.9 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily EF1G PF00647.14 XP_011277482.1 - 1.5e-43 146.8 0.1 2.5e-43 146.1 0.1 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 XP_011277482.1 - 4.3e-11 42.6 0.0 1.4e-10 40.9 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 XP_011277482.1 - 4.5e-09 36.0 0.1 2.5e-08 33.6 0.0 2.2 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 XP_011277482.1 - 1.1e-05 25.7 0.2 3.7e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Ctr PF04145.10 XP_011277484.1 - 4e-27 95.0 0.3 5.8e-27 94.5 0.2 1.2 1 0 0 1 1 1 1 Ctr copper transporter family ATP_synt_I PF03899.10 XP_011277484.1 - 5.5 7.2 10.0 2.2 8.5 0.3 2.2 2 0 0 2 2 2 0 ATP synthase I chain Proteasome PF00227.21 XP_011277485.1 - 2.4e-48 163.9 0.2 2.8e-48 163.7 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 XP_011277485.1 - 0.31 10.4 1.2 0.65 9.3 0.8 1.6 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature CDC45 PF02724.9 XP_011277485.1 - 4.3 5.2 8.6 5.3 4.9 6.0 1.2 1 0 0 1 1 1 0 CDC45-like protein UPF0047 PF01894.12 XP_011277486.1 - 3.3e-13 49.4 0.0 3.9e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 Ureidogly_hydro PF04115.7 XP_011277487.1 - 3.4e-28 98.0 0.0 4e-28 97.8 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate hydrolase Oxidored_FMN PF00724.15 XP_011277488.1 - 6.4e-98 327.8 0.0 7.3e-98 327.7 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Terminase_6 PF03237.10 XP_011277488.1 - 0.0064 15.3 0.0 0.011 14.5 0.0 1.3 1 0 0 1 1 1 1 Terminase-like family Oxidored_FMN PF00724.15 XP_011277489.1 - 1.5e-95 320.0 0.0 1.7e-95 319.8 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Rpp20 PF12328.3 XP_011277491.1 - 6.2e-22 77.7 3.8 2.5e-20 72.5 2.6 2.2 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 XP_011277491.1 - 9.6e-16 57.1 0.3 1.5e-15 56.4 0.2 1.4 1 0 0 1 1 1 1 Alba PMC2NT PF08066.7 XP_011277492.1 - 0.006 16.8 3.6 0.01 16.1 2.5 1.4 1 0 0 1 1 1 1 PMC2NT (NUC016) domain YaaC PF14175.1 XP_011277492.1 - 0.073 12.0 2.0 0.091 11.7 1.4 1.1 1 0 0 1 1 1 0 YaaC-like Protein Taxilin PF09728.4 XP_011277492.1 - 0.079 12.0 3.2 0.13 11.2 2.2 1.3 1 1 0 1 1 1 0 Myosin-like coiled-coil protein Pept_tRNA_hydro PF01195.14 XP_011277494.1 - 1.6e-38 132.0 0.1 2.2e-38 131.6 0.1 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase DpnII PF04556.7 XP_011277494.1 - 0.083 11.9 0.1 0.11 11.5 0.1 1.2 1 0 0 1 1 1 0 DpnII restriction endonuclease E1-E2_ATPase PF00122.15 XP_011277495.1 - 9.3e-16 57.5 0.0 9.3e-16 57.5 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 XP_011277495.1 - 2e-13 50.0 0.0 5.5e-13 48.6 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 XP_011277495.1 - 1.4e-12 48.1 0.1 4.2e-12 46.6 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 XP_011277495.1 - 3.5e-11 43.9 0.0 9.7e-10 39.2 0.0 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 XP_011277495.1 - 0.0035 16.9 0.2 0.024 14.2 0.1 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Dak1 PF02733.12 XP_011277496.1 - 7.4e-128 425.7 2.2 9.9e-128 425.2 1.6 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 XP_011277496.1 - 5.3e-47 159.7 0.6 2.9e-46 157.3 0.1 2.3 2 0 0 2 2 2 1 DAK2 domain TFIIA_gamma_N PF02268.11 XP_011277496.1 - 0.024 14.2 0.1 0.15 11.6 0.0 2.4 2 0 0 2 2 2 0 Transcription initiation factor IIA, gamma subunit, helical domain SSrecog PF03531.9 XP_011277497.1 - 1e-68 231.0 0.0 1.8e-68 230.2 0.0 1.4 1 0 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 XP_011277497.1 - 8.4e-30 102.6 0.1 6.4e-26 90.1 0.0 3.3 3 0 0 3 3 3 2 Histone chaperone Rttp106-like bPH_2 PF03703.9 XP_011277497.1 - 0.0076 16.2 0.0 8.9 6.4 0.0 3.5 4 0 0 4 4 4 2 Bacterial PH domain CoA_binding_2 PF13380.1 XP_011277498.1 - 1.7e-27 95.8 0.0 2e-27 95.6 0.0 1.0 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.14 XP_011277498.1 - 0.069 13.6 0.0 0.11 13.0 0.0 1.3 1 0 0 1 1 1 0 CoA binding domain DUF1649 PF07855.7 XP_011277499.1 - 6.4e-19 68.2 7.8 4e-18 65.6 2.7 2.5 2 1 0 2 2 2 2 Protein of unknown function (DUF1649) Hexokinase_1 PF00349.16 XP_011277500.1 - 1.1e-13 51.0 0.3 1.9e-13 50.2 0.2 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 XP_011277500.1 - 6.1e-10 38.7 0.5 3.4e-09 36.2 0.3 2.3 1 1 0 1 1 1 1 Hexokinase DUF2406 PF10295.4 XP_011277501.1 - 3.5e-24 85.0 0.0 6e-24 84.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein (DUF2406) Aminotran_1_2 PF00155.16 XP_011277502.1 - 2.7e-39 135.1 0.0 3.4e-39 134.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II MPC PF03650.8 XP_011277503.1 - 2.9e-46 156.3 0.1 3.3e-46 156.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) TMF_DNA_bd PF12329.3 XP_011277504.1 - 0.014 15.1 1.7 0.014 15.1 1.2 3.5 4 1 0 4 4 4 0 TATA element modulatory factor 1 DNA binding Sod_Ni PF09055.6 XP_011277504.1 - 0.075 13.4 2.2 0.2 12.0 0.7 2.1 1 1 1 2 2 2 0 Nickel-containing superoxide dismutase ABC2_membrane_3 PF12698.2 XP_011277504.1 - 0.71 8.8 9.2 0.81 8.6 6.4 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein LUC7 PF03194.10 XP_011277504.1 - 4.8 6.6 10.9 17 4.8 0.3 2.8 1 1 1 2 2 2 0 LUC7 N_terminus APC8 PF04049.8 XP_011277505.1 - 2e-35 121.6 0.6 5e-35 120.3 0.4 1.8 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.23 XP_011277505.1 - 6.5e-19 66.6 18.7 5.7e-06 25.7 0.1 6.7 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.1 XP_011277505.1 - 3.8e-17 61.7 17.4 6.6e-07 28.8 0.6 5.6 4 2 2 6 6 6 3 TPR repeat TPR_8 PF13181.1 XP_011277505.1 - 7.5e-14 50.3 20.4 0.012 15.3 0.0 8.4 6 1 2 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.12 XP_011277505.1 - 1.7e-13 49.3 15.7 0.00064 19.4 0.0 8.2 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_7 PF13176.1 XP_011277505.1 - 2.7e-09 36.1 4.3 0.044 13.5 0.0 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 XP_011277505.1 - 2.1e-08 34.6 0.0 0.0013 19.3 0.0 5.3 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 XP_011277505.1 - 2.3e-08 33.9 0.0 0.0096 16.4 0.0 6.2 5 1 1 6 6 6 2 Tetratricopeptide repeat Apc3 PF12895.2 XP_011277505.1 - 5.9e-08 32.7 24.8 0.021 14.9 0.0 6.4 4 1 2 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 XP_011277505.1 - 2.1e-06 27.5 17.4 0.0025 17.6 0.4 5.4 5 2 2 7 7 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 XP_011277505.1 - 3.3e-06 26.8 14.0 0.032 14.4 0.1 6.9 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_19 PF14559.1 XP_011277505.1 - 2.3e-05 24.6 1.0 9.9 6.5 0.0 5.9 6 1 2 8 8 7 1 Tetratricopeptide repeat TPR_6 PF13174.1 XP_011277505.1 - 0.26 11.8 14.2 1.1e+02 3.5 0.0 8.4 10 0 0 10 10 9 0 Tetratricopeptide repeat PROCN PF08083.6 XP_011277506.1 - 6.4e-221 732.9 8.7 1.6e-220 731.6 6.1 1.7 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 XP_011277506.1 - 2.2e-125 416.5 1.6 4e-125 415.6 1.1 1.5 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 XP_011277506.1 - 1.2e-88 294.4 0.3 2.9e-88 293.2 0.2 1.7 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 XP_011277506.1 - 3.6e-81 270.1 3.4 8.2e-81 269.0 2.4 1.6 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 XP_011277506.1 - 8.9e-67 222.8 0.1 3.3e-66 221.0 0.0 2.0 2 0 0 2 2 2 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.6 XP_011277506.1 - 1.3e-44 150.9 0.1 4.5e-44 149.1 0.0 2.1 2 0 0 2 2 2 1 PROCT (NUC072) domain RRM_4 PF10598.4 XP_011277506.1 - 9.5e-44 147.1 0.2 2.3e-43 145.9 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 JAB PF01398.16 XP_011277506.1 - 0.00054 19.6 0.0 0.0014 18.3 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease BAR PF03114.13 XP_011277507.1 - 1.3e-22 80.4 6.0 1.9e-22 79.8 4.1 1.3 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 XP_011277507.1 - 8e-15 53.9 0.3 3e-14 52.1 0.1 2.1 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 XP_011277507.1 - 1.5e-12 46.8 0.1 3e-12 45.9 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 XP_011277507.1 - 1.8e-10 40.1 0.1 5.2e-10 38.6 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain Securin PF04856.8 XP_011277507.1 - 0.088 12.5 2.7 0.14 11.8 1.9 1.3 1 0 0 1 1 1 0 Securin sister-chromatid separation inhibitor PolC_DP2 PF03833.8 XP_011277507.1 - 0.11 10.1 1.0 0.16 9.6 0.7 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Aminotran_3 PF00202.16 XP_011277508.1 - 1.9e-65 220.9 0.0 2.6e-65 220.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III NifZ PF04319.8 XP_011277508.1 - 0.084 12.2 0.4 4 6.8 0.1 3.1 3 0 0 3 3 3 0 NifZ domain DnaJ PF00226.26 XP_011277509.1 - 2.7e-22 78.2 4.2 1.1e-21 76.2 2.9 2.2 1 0 0 1 1 1 1 DnaJ domain Med15 PF09606.5 XP_011277509.1 - 1.3 7.1 28.0 1.7 6.7 19.4 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Trypan_glycop_C PF10659.4 XP_011277509.1 - 3.1 8.1 8.5 32 4.8 3.2 2.4 2 0 0 2 2 2 0 Trypanosome variant surface glycoprotein C-terminal domain Peptidase_M28 PF04389.12 XP_011277510.1 - 7.7e-33 113.7 0.0 1.2e-32 113.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 XP_011277510.1 - 3.1e-13 49.2 0.1 5.8e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 XP_011277510.1 - 0.00065 19.2 0.0 0.001 18.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 XP_011277510.1 - 0.048 12.4 0.0 0.12 11.1 0.0 1.6 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase COMPASS-Shg1 PF05205.7 XP_011277511.1 - 7.7e-21 74.3 1.1 1.1e-20 73.9 0.7 1.3 1 1 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 Choline_kin_N PF04428.9 XP_011277511.1 - 0.075 12.5 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Choline kinase N terminus Cullin PF00888.17 XP_011277512.1 - 3.5e-61 207.4 23.9 5.5e-61 206.8 16.5 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 XP_011277512.1 - 9.3e-15 54.2 0.3 3.7e-14 52.2 0.2 2.1 1 0 0 1 1 1 1 Cullin protein neddylation domain HTH_34 PF13601.1 XP_011277512.1 - 0.03 14.3 0.3 0.23 11.4 0.1 2.4 2 0 0 2 2 2 0 Winged helix DNA-binding domain RhoGAP PF00620.22 XP_011277513.1 - 6.8e-42 142.6 0.0 1.9e-41 141.2 0.0 1.8 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.18 XP_011277513.1 - 2.5e-12 46.7 0.5 7.9e-12 45.2 0.3 1.9 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain DUF919 PF06034.6 XP_011277513.1 - 0.068 12.7 2.0 0.29 10.7 1.4 2.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) UBX PF00789.15 XP_011277514.1 - 2.5e-17 62.7 0.0 6.7e-17 61.3 0.0 1.8 1 0 0 1 1 1 1 UBX domain Thioredoxin_7 PF13899.1 XP_011277514.1 - 0.00057 19.8 0.0 0.0012 18.8 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like CAF-1_p150 PF11600.3 XP_011277514.1 - 0.55 9.5 31.7 3.3 7.0 22.0 2.2 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Pkinase PF00069.20 XP_011277515.1 - 1.7e-53 181.4 0.0 2.7e-53 180.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011277515.1 - 4.1e-24 85.0 0.0 6e-24 84.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 XP_011277515.1 - 3.6e-06 26.1 0.0 6.5e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 XP_011277515.1 - 0.0071 15.4 0.0 0.019 14.0 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 XP_011277515.1 - 0.062 12.1 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 XP_011277515.1 - 0.075 12.7 0.0 0.32 10.6 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Snf7 PF03357.16 XP_011277517.1 - 1.7e-16 60.0 16.1 2.9e-16 59.3 11.2 1.3 1 0 0 1 1 1 1 Snf7 DUF2743 PF10899.3 XP_011277517.1 - 0.29 10.4 5.4 0.081 12.2 0.7 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2743) DUF2120 PF09893.4 XP_011277517.1 - 3.9 7.4 8.9 0.19 11.6 0.2 2.6 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) GWT1 PF06423.7 XP_011277519.1 - 2.7e-41 140.8 2.3 2.7e-41 140.8 1.6 2.9 2 1 0 2 2 2 1 GWT1 UvrD_C PF13361.1 XP_011277520.1 - 1.3e-64 218.8 0.1 1.3e-64 218.8 0.1 2.8 4 0 0 4 4 4 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 XP_011277520.1 - 1.2e-48 166.0 11.2 1.2e-48 166.0 3.9 2.6 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 XP_011277520.1 - 2e-11 43.9 0.0 8.8e-11 41.8 0.0 2.2 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 XP_011277520.1 - 0.036 13.5 1.9 0.88 9.0 0.0 3.1 3 1 0 3 3 3 0 Viral (Superfamily 1) RNA helicase LSM PF01423.17 XP_011277521.1 - 6.2e-17 60.9 0.5 8.7e-17 60.4 0.4 1.2 1 0 0 1 1 1 1 LSM domain LSM14 PF12701.2 XP_011277521.1 - 0.038 13.7 0.3 0.073 12.8 0.2 1.6 1 1 0 1 1 1 0 Scd6-like Sm domain CHZ PF09649.5 XP_011277522.1 - 2.1e-18 65.2 1.7 2.1e-18 65.2 1.2 2.9 4 0 0 4 4 4 1 Histone chaperone domain CHZ Presenilin PF01080.12 XP_011277522.1 - 1.3 7.7 13.9 1.6 7.4 9.6 1.3 1 0 0 1 1 1 0 Presenilin Ras PF00071.17 XP_011277523.1 - 3.9e-60 201.9 0.2 4.6e-60 201.6 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 XP_011277523.1 - 5.7e-21 75.2 0.0 9.5e-21 74.5 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 XP_011277523.1 - 1.2e-12 47.4 0.1 1.6e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 XP_011277523.1 - 1.2e-07 31.7 0.1 2.4e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 XP_011277523.1 - 0.00041 19.8 0.1 0.0014 18.0 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 XP_011277523.1 - 0.0011 18.2 0.1 0.0013 17.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF258 PF03193.11 XP_011277523.1 - 0.0025 16.9 0.1 0.0065 15.6 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 XP_011277523.1 - 0.0035 17.4 0.2 0.012 15.7 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.1 XP_011277523.1 - 0.0042 16.2 0.2 0.0085 15.1 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain NTPase_1 PF03266.10 XP_011277523.1 - 0.01 15.5 0.1 0.015 14.9 0.0 1.3 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.1 XP_011277523.1 - 0.011 16.0 0.0 0.025 14.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 XP_011277523.1 - 0.012 15.6 0.4 0.034 14.1 0.3 1.8 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 XP_011277523.1 - 0.012 15.8 0.1 0.024 14.9 0.0 1.5 1 1 0 1 1 1 0 ABC transporter PduV-EutP PF10662.4 XP_011277523.1 - 0.036 13.5 0.0 0.082 12.4 0.0 1.7 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 XP_011277523.1 - 0.046 12.9 0.0 0.071 12.3 0.0 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF1128 PF06569.6 XP_011277523.1 - 0.047 13.4 0.7 0.15 11.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1128) FeoB_N PF02421.13 XP_011277523.1 - 0.07 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B KAP_NTPase PF07693.9 XP_011277523.1 - 0.08 11.9 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain AAA_14 PF13173.1 XP_011277523.1 - 0.08 12.8 0.1 0.17 11.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain Septin PF00735.13 XP_011277523.1 - 0.083 11.8 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Septin cobW PF02492.14 XP_011277523.1 - 0.12 11.7 0.1 0.37 10.2 0.1 1.8 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SPT16 PF08644.6 XP_011277524.1 - 1e-49 168.3 0.0 1e-49 168.3 0.0 3.3 3 1 1 4 4 4 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 XP_011277524.1 - 1.4e-44 151.5 1.3 1.4e-44 151.5 0.9 2.6 2 0 0 2 2 2 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 XP_011277524.1 - 1.1e-21 77.3 0.0 1.9e-21 76.6 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.7 XP_011277524.1 - 1.3e-20 73.1 4.4 1.9e-20 72.6 0.0 3.4 4 0 0 4 4 4 1 Histone chaperone Rttp106-like MFS_1 PF07690.11 XP_011277525.1 - 3.5e-42 144.3 32.8 6.3e-41 140.2 23.8 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 XP_011277525.1 - 5.3e-12 44.7 17.1 1.2e-11 43.5 11.8 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3681 PF12442.3 XP_011277525.1 - 0.064 13.4 0.1 0.3 11.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3681) ESSS PF10183.4 XP_011277525.1 - 0.37 11.2 0.1 0.37 11.2 0.1 2.5 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Velvet PF11754.3 XP_011277526.1 - 1.3e-47 162.0 0.1 1.3e-47 162.0 0.1 1.9 2 0 0 2 2 2 1 Velvet factor Fungal_trans PF04082.13 XP_011277527.1 - 7.2e-08 31.6 0.6 1.5e-07 30.6 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 XP_011277527.1 - 5e-07 29.5 9.5 1e-06 28.5 6.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TMF_TATA_bd PF12325.3 XP_011277528.1 - 3.3e-33 113.9 14.1 3.3e-33 113.9 9.8 7.6 3 1 4 7 7 7 4 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 XP_011277528.1 - 1.4e-13 50.4 22.7 1.4e-13 50.4 15.8 10.5 5 4 4 9 9 9 2 TATA element modulatory factor 1 DNA binding IncA PF04156.9 XP_011277528.1 - 0.00041 19.9 98.3 0.00048 19.7 7.3 5.8 2 1 3 5 5 5 3 IncA protein ATG16 PF08614.6 XP_011277528.1 - 0.0044 16.8 17.6 0.0044 16.8 12.2 6.8 4 2 3 7 7 7 3 Autophagy protein 16 (ATG16) Tropomyosin_1 PF12718.2 XP_011277528.1 - 0.0045 16.8 13.9 0.0045 16.8 9.6 6.3 4 2 4 8 8 8 4 Tropomyosin like Pribosyltran PF00156.22 XP_011277529.1 - 0.00026 20.7 0.3 0.0014 18.3 0.2 2.0 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Utp12 PF04003.7 XP_011277530.1 - 1.6e-07 31.2 1.1 2.9e-07 30.3 0.7 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family BBS2_Mid PF14783.1 XP_011277530.1 - 5e-05 23.0 1.3 0.14 11.9 0.0 3.2 2 1 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region TFIIA PF03153.8 XP_011277530.1 - 2.3 8.0 13.8 0.22 11.3 5.9 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit IBN_N PF03810.14 XP_011277531.1 - 3.2e-18 65.4 0.0 4.7e-16 58.4 0.0 3.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 XP_011277531.1 - 0.00034 20.5 6.7 0.00052 19.9 0.3 4.2 3 1 1 4 4 4 1 Exportin 1-like protein MDM31_MDM32 PF08118.6 XP_011277533.1 - 1.2e-252 838.7 10.7 1.4e-252 838.5 7.4 1.0 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins CDC73 PF05179.9 XP_011277534.1 - 5.7e-61 206.2 10.7 5.7e-61 206.2 7.4 1.4 2 0 0 2 2 2 1 RNA pol II accessory factor, Cdc73 family P22_AR_N PF10547.4 XP_011277534.1 - 0.014 15.2 0.1 0.038 13.8 0.0 1.7 1 0 0 1 1 1 0 P22_AR N-terminal domain ETRAMP PF09716.5 XP_011277534.1 - 4.8 7.2 7.9 0.31 11.0 1.4 2.2 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) tRNA-synt_2b PF00587.20 XP_011277535.1 - 4.8e-50 169.5 0.2 7.8e-50 168.8 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 XP_011277535.1 - 1.7e-17 63.0 0.3 3.6e-17 62.0 0.2 1.6 1 0 0 1 1 1 1 Anticodon binding domain APG17 PF04108.7 XP_011277536.1 - 6.2e-48 163.5 33.6 8.4e-48 163.1 23.3 1.1 1 0 0 1 1 1 1 Autophagy protein Apg17 zf-C4H2 PF10146.4 XP_011277536.1 - 0.069 13.1 12.8 0.023 14.7 3.1 2.4 2 0 0 2 2 2 0 Zinc finger-containing protein Occludin_ELL PF07303.8 XP_011277536.1 - 3.7 8.3 20.7 0.16 12.6 0.9 4.9 1 1 3 5 5 5 0 Occludin homology domain DUF2400 PF09674.5 XP_011277536.1 - 6.5 6.3 18.8 0.042 13.5 1.4 3.4 1 1 3 4 4 4 0 Protein of unknown function (DUF2400) GCFC PF07842.7 XP_011277537.1 - 5.5e-32 111.2 8.7 1e-31 110.3 6.0 1.4 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.18 XP_011277537.1 - 5.2e-10 38.9 1.8 5.2e-10 38.9 1.3 1.7 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 XP_011277537.1 - 0.12 12.2 0.1 0.35 10.7 0.1 1.8 1 0 0 1 1 1 0 DExH-box splicing factor binding site Mucin PF01456.12 XP_011277537.1 - 2.4 7.9 22.9 5.1 6.8 15.9 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein CHCH PF06747.8 XP_011277538.1 - 1.6e-06 27.8 5.2 3.1e-06 26.9 3.6 1.5 1 0 0 1 1 1 1 CHCH domain PGA2 PF07543.7 XP_011277538.1 - 0.33 10.7 5.6 0.064 13.0 1.0 1.8 2 0 0 2 2 2 0 Protein trafficking PGA2 DUF1510 PF07423.6 XP_011277538.1 - 0.55 9.5 10.8 0.056 12.8 2.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Menin PF05053.8 XP_011277538.1 - 0.75 7.8 6.2 0.06 11.5 0.9 1.6 2 0 0 2 2 2 0 Menin SpoIIIAH PF12685.2 XP_011277538.1 - 1.1 8.7 11.0 4.1 6.8 7.7 1.8 1 1 0 1 1 1 0 SpoIIIAH-like protein DUF3449 PF11931.3 XP_011277538.1 - 1.2 8.6 6.6 0.19 11.1 1.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) Ycf1 PF05758.7 XP_011277538.1 - 4.3 4.9 7.9 6.6 4.3 5.4 1.6 1 1 0 1 1 1 0 Ycf1 MRI PF15325.1 XP_011277538.1 - 7.9 7.4 11.8 5.5 8.0 3.8 2.2 2 0 0 2 2 2 0 Modulator of retrovirus infection Synaptobrevin PF00957.16 XP_011277539.1 - 1.4e-15 56.6 0.2 2.3e-15 55.9 0.2 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 XP_011277539.1 - 2.1e-14 52.8 0.0 3.5e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Tropomyosin_1 PF12718.2 XP_011277540.1 - 0.0022 17.8 10.3 0.0049 16.7 7.1 1.6 1 1 0 1 1 1 1 Tropomyosin like IMD PF08397.6 XP_011277540.1 - 0.011 15.0 4.1 0.014 14.7 2.8 1.1 1 0 0 1 1 1 0 IRSp53/MIM homology domain Anti-adapt_IraP PF10796.4 XP_011277540.1 - 0.027 14.8 2.5 0.054 13.8 1.7 1.5 1 0 0 1 1 1 0 Sigma-S stabilisation anti-adaptor protein CesA PF11439.3 XP_011277540.1 - 0.045 13.6 5.3 0.12 12.2 3.5 1.8 1 1 1 2 2 2 0 Type III secretion system filament chaperone CesA DUF1657 PF07870.6 XP_011277540.1 - 0.052 13.2 0.6 0.27 10.9 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1657) DUF148 PF02520.12 XP_011277540.1 - 0.063 13.0 2.6 0.099 12.4 1.8 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF148 BLOC1_2 PF10046.4 XP_011277540.1 - 0.087 12.9 7.4 0.12 12.5 5.1 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TMF_DNA_bd PF12329.3 XP_011277540.1 - 0.12 12.1 12.3 0.09 12.5 6.0 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding MerR-DNA-bind PF09278.6 XP_011277540.1 - 0.13 12.6 1.2 0.36 11.2 0.3 2.1 1 1 2 3 3 3 0 MerR, DNA binding V_ATPase_I PF01496.14 XP_011277540.1 - 0.14 10.0 3.6 0.14 10.0 2.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family KMP11 PF03037.11 XP_011277540.1 - 0.15 12.7 2.2 0.25 11.9 1.5 1.4 1 0 0 1 1 1 0 Kinetoplastid membrane protein 11 Med9 PF07544.8 XP_011277540.1 - 0.51 10.1 7.4 0.36 10.6 3.5 1.8 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF948 PF06103.6 XP_011277540.1 - 0.55 10.1 2.8 0.48 10.3 1.1 1.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Fzo_mitofusin PF04799.8 XP_011277540.1 - 0.72 9.2 5.4 0.97 8.7 3.7 1.2 1 0 0 1 1 1 0 fzo-like conserved region MbeB_N PF04837.7 XP_011277540.1 - 0.8 9.8 4.6 0.32 11.1 0.2 2.3 3 0 0 3 3 3 0 MbeB-like, N-term conserved region Pox_A_type_inc PF04508.7 XP_011277540.1 - 6 6.9 6.9 3.6 7.6 0.2 3.6 2 1 3 5 5 5 0 Viral A-type inclusion protein repeat FlaC_arch PF05377.6 XP_011277540.1 - 6.1 6.8 10.4 1.9 8.4 3.3 2.3 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) FlxA PF14282.1 XP_011277540.1 - 8.1 6.4 12.4 0.35 10.8 4.5 1.8 2 0 0 2 2 2 0 FlxA-like protein DUF1691 PF07950.6 XP_011277541.1 - 2.3e-34 117.6 4.2 7.8e-20 70.8 0.7 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) APG12 PF04110.8 XP_011277542.1 - 2.8e-17 62.6 0.1 5.9e-17 61.6 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 DUF4330 PF14221.1 XP_011277542.1 - 0.1 12.4 0.3 0.16 11.7 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4330) Rpp20 PF12328.3 XP_011277542.1 - 0.2 11.2 1.9 1.3 8.6 0.0 2.3 2 0 0 2 2 2 0 Rpp20 subunit of nuclear RNase MRP and P CENP-B_dimeris PF09026.5 XP_011277542.1 - 0.91 9.7 6.6 1.9 8.7 4.6 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 XP_011277542.1 - 7.8 5.9 9.3 7.2 6.1 3.7 2.2 2 0 0 2 2 2 0 Nucleoplasmin Apc5 PF12862.2 XP_011277543.1 - 1.5e-32 111.2 6.0 1.5e-32 111.2 4.2 2.4 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 5 HATPase_c_3 PF13589.1 XP_011277544.1 - 5.1e-14 52.0 0.0 1.3e-13 50.7 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.6 XP_011277544.1 - 2.2e-10 40.3 0.0 1e-09 38.1 0.0 2.1 1 1 0 1 1 1 1 MutL C terminal dimerisation domain HATPase_c PF02518.21 XP_011277544.1 - 9.2e-10 38.2 0.0 2.4e-09 36.9 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.14 XP_011277544.1 - 0.00022 20.6 0.2 0.0012 18.3 0.0 2.1 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain Clp1 PF06807.9 XP_011277545.1 - 1.3e-18 67.4 0.1 2.7e-18 66.4 0.1 1.5 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 XP_011277545.1 - 8.3e-06 25.5 0.6 0.00015 21.4 0.0 2.7 1 1 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 XP_011277545.1 - 0.0023 17.5 0.0 0.015 14.8 0.0 2.1 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.1 XP_011277545.1 - 0.0039 17.1 0.0 0.014 15.3 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 XP_011277545.1 - 0.0091 15.4 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family G-alpha PF00503.15 XP_011277545.1 - 0.02 13.6 0.0 0.033 12.8 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit ABC_tran PF00005.22 XP_011277545.1 - 0.022 15.0 0.0 0.052 13.8 0.0 1.6 1 0 0 1 1 1 0 ABC transporter tRNA-Thr_ED PF08915.6 XP_011277545.1 - 0.039 13.9 0.8 0.076 12.9 0.5 1.4 1 0 0 1 1 1 0 Archaea-specific editing domain of threonyl-tRNA synthetase AAA_28 PF13521.1 XP_011277545.1 - 0.04 13.8 0.0 0.074 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.22 XP_011277545.1 - 0.05 13.0 0.0 0.091 12.1 0.0 1.4 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_14 PF13173.1 XP_011277545.1 - 0.05 13.5 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 XP_011277545.1 - 0.059 13.1 0.1 0.19 11.4 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain AAA_17 PF13207.1 XP_011277545.1 - 0.065 14.0 0.2 0.25 12.1 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_35 PF14516.1 XP_011277545.1 - 0.075 11.6 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain PduV-EutP PF10662.4 XP_011277545.1 - 0.11 12.0 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ATP-synt_ab PF00006.20 XP_011277545.1 - 0.13 11.7 0.0 0.17 11.3 0.0 1.3 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Rhodanese PF00581.15 XP_011277546.1 - 2.9e-17 63.0 0.0 6.5e-08 32.9 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain SET PF00856.23 XP_011277547.1 - 1.5e-12 48.1 0.3 3e-09 37.3 0.0 2.3 2 1 1 3 3 3 3 SET domain ComC PF03047.9 XP_011277547.1 - 0.027 13.8 0.6 0.027 13.8 0.4 1.9 2 0 0 2 2 2 0 COMC family Tau95 PF09734.4 XP_011277547.1 - 0.039 13.2 0.2 0.052 12.8 0.2 1.1 1 0 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit S_tail_recep_bd PF14928.1 XP_011277548.1 - 0.052 13.7 0.2 0.12 12.6 0.1 1.5 1 0 0 1 1 1 0 Short tail fibre protein receptor-binding domain DNA_pol_B PF00136.16 XP_011277549.1 - 4.6e-96 322.4 0.2 7.1e-96 321.7 0.2 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 XP_011277549.1 - 1.6e-20 73.2 6.2 2.8e-10 39.5 0.1 2.9 3 0 0 3 3 3 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 XP_011277549.1 - 2.3e-16 59.5 10.9 4.6e-16 58.5 7.6 1.5 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DUF336 PF03928.9 XP_011277550.1 - 1e-06 28.6 0.0 1.3e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF336) LETM1 PF07766.8 XP_011277552.1 - 1.8e-05 23.9 3.9 0.00019 20.6 1.1 2.5 1 1 1 2 2 2 2 LETM1-like protein Pkinase PF00069.20 XP_011277553.1 - 7.8e-60 202.2 0.0 9.8e-59 198.6 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 XP_011277553.1 - 1.1e-22 80.3 0.0 2.4e-21 75.9 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 XP_011277553.1 - 0.012 15.3 0.1 0.048 13.3 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 XP_011277553.1 - 0.12 11.3 0.1 0.26 10.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WD40 PF00400.27 XP_011277554.1 - 5e-63 206.9 13.8 2.1e-11 43.2 0.3 7.5 7 1 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 XP_011277554.1 - 3.7e-06 25.3 6.3 0.0011 17.2 0.2 3.1 2 1 1 3 3 3 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 XP_011277554.1 - 2.3e-05 22.8 0.0 4.5e-05 21.9 0.0 1.5 2 0 0 2 2 2 1 Cytochrome D1 heme domain DUF3573 PF12097.3 XP_011277554.1 - 0.025 13.1 2.0 0.036 12.6 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) V_ATPase_I PF01496.14 XP_011277555.1 - 3.7e-295 980.7 10.2 4.2e-295 980.5 7.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Rootletin PF15035.1 XP_011277555.1 - 0.01 15.8 0.2 0.01 15.8 0.1 2.4 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion PTPA PF03095.10 XP_011277556.1 - 8.8e-117 389.5 0.8 1e-116 389.3 0.5 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein MOZ_SAS PF01853.13 XP_011277557.1 - 1.7e-89 298.0 0.5 2.5e-89 297.5 0.4 1.3 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 XP_011277557.1 - 3e-22 78.0 0.3 7e-22 76.8 0.2 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_1 PF00583.19 XP_011277557.1 - 0.027 14.5 0.0 0.064 13.2 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family TT_ORF2 PF02957.10 XP_011277557.1 - 0.13 12.9 1.2 0.32 11.6 0.8 1.6 1 0 0 1 1 1 0 TT viral ORF2 WD40 PF00400.27 XP_011277558.1 - 2.7e-55 182.3 9.7 1.5e-10 40.5 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 XP_011277558.1 - 6.2e-07 28.5 0.6 0.036 12.8 0.1 3.6 2 2 1 3 3 3 3 Nup133 N terminal like Nup160 PF11715.3 XP_011277558.1 - 0.003 15.7 6.3 0.22 9.6 1.0 4.0 1 1 0 3 3 3 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 XP_011277558.1 - 0.059 12.8 0.5 11 5.3 0.0 3.0 2 1 0 3 3 3 0 PQQ-like domain Ricin_B_lectin PF00652.17 XP_011277558.1 - 0.12 12.3 0.6 4.9 7.2 0.0 3.2 3 1 0 3 3 3 0 Ricin-type beta-trefoil lectin domain TruD PF01142.13 XP_011277559.1 - 9.1e-66 222.0 0.1 1.2e-62 211.7 0.0 3.5 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) Pet20 PF08692.5 XP_011277560.1 - 6.7e-12 45.5 10.3 1.8e-06 27.9 0.1 3.2 2 1 1 3 3 3 2 Mitochondrial protein Pet20 DUF349 PF03993.7 XP_011277560.1 - 0.1 12.7 4.0 0.47 10.6 2.8 2.1 1 1 0 1 1 1 0 Domain of Unknown Function (DUF349) Cyto_heme_lyase PF01265.12 XP_011277560.1 - 0.55 9.7 8.9 0.057 12.9 2.9 1.6 2 0 0 2 2 2 0 Cytochrome c/c1 heme lyase RNA_pol_Rpc82 PF05645.8 XP_011277560.1 - 5.5 6.4 12.9 5.9 6.3 3.6 2.1 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 DUF4130 PF13566.1 XP_011277561.1 - 0.02 14.4 0.1 0.039 13.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4130 LRR19-TM PF15176.1 XP_011277561.1 - 0.23 11.1 1.9 0.6 9.8 1.3 1.6 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Methyltransf_15 PF09445.5 XP_011277562.1 - 1.2e-50 171.3 1.0 1.6e-50 170.9 0.0 1.7 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase Methyltransf_31 PF13847.1 XP_011277562.1 - 1.5e-08 34.3 0.0 3.2e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 XP_011277562.1 - 4.6e-08 33.3 0.1 1.8e-07 31.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 XP_011277562.1 - 6.7e-08 33.1 0.0 1.5e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 XP_011277562.1 - 1.4e-07 31.2 0.0 2.7e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 XP_011277562.1 - 4.9e-07 29.7 0.0 8.6e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 XP_011277562.1 - 3.6e-06 26.4 0.0 1.9e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_11 PF08241.7 XP_011277562.1 - 0.00015 22.1 0.7 0.00055 20.3 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain Cons_hypoth95 PF03602.10 XP_011277562.1 - 0.0042 16.5 0.0 0.0092 15.3 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Ubie_methyltran PF01209.13 XP_011277562.1 - 0.0099 15.0 0.1 0.019 14.0 0.1 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Yae1_N PF09811.4 XP_011277562.1 - 0.016 14.6 4.1 0.032 13.7 2.8 1.4 1 0 0 1 1 1 0 Essential protein Yae1, N terminal Met_10 PF02475.11 XP_011277562.1 - 0.017 14.6 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Kinesin PF00225.18 XP_011277563.1 - 8.9e-103 343.4 2.4 8.9e-103 343.4 1.7 2.1 2 0 0 2 2 2 1 Kinesin motor domain Cep57_MT_bd PF06657.8 XP_011277563.1 - 4.7 7.2 11.0 0.16 11.9 0.4 3.3 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Asp PF00026.18 XP_011277564.1 - 1.1e-103 346.8 0.0 1.3e-103 346.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 XP_011277564.1 - 9.3e-12 45.2 0.0 2.2e-11 43.9 0.0 1.7 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 XP_011277564.1 - 2.3e-06 28.0 0.0 0.00045 20.6 0.0 2.5 2 0 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 XP_011277564.1 - 0.019 14.5 0.0 0.098 12.2 0.0 2.2 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal Aminotran_4 PF01063.14 XP_011277565.1 - 7.2e-27 94.3 0.0 9.5e-27 93.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV MFS_1 PF07690.11 XP_011277566.1 - 6.9e-21 74.3 72.0 7e-19 67.7 27.3 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 XP_011277566.1 - 1.8e-08 33.2 28.9 0.00012 20.6 9.5 2.2 2 0 0 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.19 XP_011277566.1 - 1.5e-06 27.0 20.0 1.6e-05 23.6 2.4 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter Pox_A14 PF05767.7 XP_011277566.1 - 0.58 10.1 4.3 6.6 6.7 0.3 3.2 2 1 0 2 2 2 0 Poxvirus virion envelope protein A14 MFS_1 PF07690.11 XP_011277567.1 - 3.4e-27 95.0 49.2 2.2e-23 82.5 19.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 XP_011277567.1 - 2.6e-12 45.8 23.4 1.1e-11 43.8 4.2 2.4 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_1 PF07690.11 XP_011277568.1 - 7.3e-25 87.4 56.8 1.7e-21 76.3 25.9 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 XP_011277568.1 - 2e-06 26.4 23.1 4e-05 22.1 4.3 2.2 1 1 1 2 2 2 2 MFS/sugar transport protein AA_permease PF00324.16 XP_011277569.1 - 3e-92 309.4 41.8 3.7e-92 309.1 29.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 XP_011277569.1 - 4.2e-24 84.8 45.2 5.7e-24 84.4 31.4 1.2 1 0 0 1 1 1 1 Amino acid permease Orthoreo_P10 PF07204.6 XP_011277569.1 - 0.79 9.5 3.5 0.76 9.5 1.1 2.0 2 0 0 2 2 2 0 Orthoreovirus membrane fusion protein p10 Myosin_head PF00063.16 XP_011277570.1 - 1.9e-223 743.4 12.5 2.8e-223 742.8 8.7 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 XP_011277570.1 - 3.1e-43 147.4 2.1 7e-43 146.2 0.2 2.3 2 0 0 2 2 2 1 Myosin tail SH3_1 PF00018.23 XP_011277570.1 - 6.6e-13 47.8 0.2 1.5e-12 46.7 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 XP_011277570.1 - 3.3e-11 42.5 0.2 1e-10 41.0 0.1 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 XP_011277570.1 - 1.7e-08 33.7 0.0 4.1e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 XP_011277570.1 - 0.00074 19.6 0.4 0.0021 18.2 0.3 1.8 1 0 0 1 1 1 1 Bacterial SH3 domain AAA_22 PF13401.1 XP_011277570.1 - 0.0028 17.7 0.1 0.011 15.9 0.1 2.1 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 XP_011277570.1 - 0.02 13.9 0.3 0.067 12.2 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin ABC_tran PF00005.22 XP_011277570.1 - 0.029 14.6 0.5 0.42 10.9 0.0 3.2 3 0 0 3 3 3 0 ABC transporter NACHT PF05729.7 XP_011277570.1 - 0.044 13.4 0.0 0.15 11.6 0.0 2.0 1 1 0 1 1 1 0 NACHT domain Hpr_kinase_C PF07475.7 XP_011277570.1 - 0.054 12.8 0.5 5.2 6.3 0.0 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_17 PF13207.1 XP_011277570.1 - 0.074 13.8 0.0 0.28 12.0 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 XP_011277570.1 - 0.096 12.4 0.0 0.32 10.7 0.0 1.9 2 0 0 2 2 2 0 Part of AAA domain AAA_16 PF13191.1 XP_011277570.1 - 0.13 12.2 0.0 0.35 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain IQ PF00612.22 XP_011277570.1 - 0.58 9.9 13.7 1 9.1 0.6 2.6 1 1 1 2 2 2 0 IQ calmodulin-binding motif ESR1_C PF12743.2 XP_011277571.1 - 0.27 10.8 0.0 0.27 10.8 0.0 1.9 2 0 0 2 2 2 0 Oestrogen-type nuclear receptor final C-terminal Spc24 PF08286.6 XP_011277572.1 - 1.3e-14 53.8 11.6 1.3e-14 53.8 8.0 2.3 1 1 1 2 2 2 1 Spc24 subunit of Ndc80 DUF4254 PF14063.1 XP_011277572.1 - 0.14 11.7 7.0 0.35 10.4 4.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4254) NusB PF01029.13 XP_011277572.1 - 0.19 11.6 8.2 0.4 10.6 5.6 1.7 1 1 0 1 1 1 0 NusB family V_ATPase_I PF01496.14 XP_011277572.1 - 0.78 7.5 10.2 0.89 7.3 7.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family L31 PF09784.4 XP_011277573.1 - 4.6e-43 145.4 1.8 5.1e-43 145.3 1.2 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 Hap4_Hap_bind PF10297.4 XP_011277574.1 - 1.1e-07 31.3 5.6 1.1e-07 31.3 3.9 2.0 2 0 0 2 2 2 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 ATP-synt_D PF01813.12 XP_011277574.1 - 1.1 8.7 9.2 0.12 11.8 1.0 2.2 2 0 0 2 2 2 0 ATP synthase subunit D Sdh_cyt PF01127.17 XP_011277575.1 - 4e-26 91.2 0.7 5.2e-26 90.8 0.5 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Abhydrolase_1 PF00561.15 XP_011277576.1 - 2.5e-21 76.2 0.0 3.4e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.11 XP_011277576.1 - 1.1e-19 69.5 0.1 1.9e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 XP_011277576.1 - 0.00018 21.4 0.0 0.00031 20.6 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 XP_011277576.1 - 0.00028 20.4 0.0 0.0052 16.2 0.0 2.1 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 XP_011277576.1 - 0.047 13.1 0.2 9.7 5.5 0.0 2.5 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase JmjC PF02373.17 XP_011277577.1 - 4.7e-10 39.7 0.0 4.9e-09 36.4 0.0 2.5 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.1 XP_011277577.1 - 7.4e-10 38.7 0.1 1.5e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Cupin-like domain F-box-like PF12937.2 XP_011277577.1 - 1.1e-05 25.0 0.0 4.4e-05 23.1 0.1 2.1 2 0 0 2 2 2 1 F-box-like Cupin_2 PF07883.6 XP_011277577.1 - 0.059 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Cupin domain GSH_synth_ATP PF03917.12 XP_011277578.1 - 8e-119 396.5 0.1 9.9e-119 396.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 XP_011277578.1 - 4.5e-38 129.5 0.0 8.5e-38 128.6 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic glutathione synthase DPPIV_N PF00930.16 XP_011277578.1 - 0.05 12.1 0.0 0.079 11.5 0.0 1.2 1 0 0 1 1 1 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region EI24 PF07264.6 XP_011277579.1 - 0.0015 18.0 4.2 0.0024 17.3 2.9 1.3 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF3273 PF11677.3 XP_011277579.1 - 0.047 12.9 0.0 0.074 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3273) TauD PF02668.11 XP_011277580.1 - 1.1e-52 179.2 0.1 1.4e-52 178.8 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.1 XP_011277580.1 - 0.00069 20.0 0.0 0.29 11.6 0.0 2.4 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily SNF2_N PF00176.18 XP_011277581.1 - 3.8e-63 213.0 0.1 9.1e-63 211.8 0.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 XP_011277581.1 - 1.6e-15 56.7 0.0 5.2e-15 55.0 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RCC1 PF00415.13 XP_011277582.1 - 1e-29 102.4 16.1 2.1e-07 31.0 0.0 6.6 6 1 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 XP_011277582.1 - 1.3e-19 69.2 15.9 1.7e-08 33.8 0.2 6.3 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat DUF775 PF05603.7 XP_011277583.1 - 1e-53 181.9 1.2 1.3e-53 181.5 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF775) TALPID3 PF15324.1 XP_011277584.1 - 3.4 4.9 34.0 5.7 4.1 23.6 1.3 1 0 0 1 1 1 0 Hedgehog signalling target Codanin-1_C PF15296.1 XP_011277585.1 - 0.02 14.7 0.2 0.047 13.5 0.1 1.6 1 0 0 1 1 1 0 Codanin-1 C-terminus Peptidase_C1_2 PF03051.10 XP_011277586.1 - 7.7e-146 486.0 6.5 9.1e-146 485.8 4.5 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 XP_011277586.1 - 5.3e-06 26.4 1.6 0.044 13.6 0.3 2.8 2 1 0 2 2 2 2 Papain family cysteine protease RRM_1 PF00076.17 XP_011277587.1 - 2.8e-24 84.5 6.8 8.3e-18 63.7 0.2 4.5 3 1 1 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 XP_011277587.1 - 2.7e-16 59.2 1.4 1.9e-11 43.7 0.0 3.8 3 1 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 XP_011277587.1 - 1.6e-10 40.6 1.7 1.6e-05 24.6 0.0 3.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sds3 PF08598.6 XP_011277588.1 - 3.2e-31 108.4 9.6 3.2e-31 108.4 6.6 4.2 1 1 1 3 3 3 1 Sds3-like ARGLU PF15346.1 XP_011277588.1 - 0.04 13.6 0.4 0.04 13.6 0.2 4.2 2 1 1 4 4 4 0 Arginine and glutamate-rich 1 Ribosomal_S19 PF00203.16 XP_011277589.1 - 5.1e-31 106.1 0.2 7e-31 105.6 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 Ribosomal_60s PF00428.14 XP_011277590.1 - 7.7e-27 93.5 13.5 9e-27 93.3 9.3 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein RPOL_N PF14700.1 XP_011277590.1 - 0.079 12.1 0.1 0.085 12.0 0.0 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal ABC_ATPase PF09818.4 XP_011277590.1 - 0.14 10.6 0.9 5.6 5.4 0.0 2.0 2 0 0 2 2 2 0 Predicted ATPase of the ABC class Cys_Met_Meta_PP PF01053.15 XP_011277591.1 - 1.7e-141 470.9 0.0 2e-141 470.8 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 XP_011277591.1 - 3.8e-05 22.8 0.0 5.7e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Met_gamma_lyase PF06838.6 XP_011277591.1 - 0.00012 20.4 0.0 0.00016 20.1 0.0 1.3 1 0 0 1 1 1 1 Methionine gamma-lyase DegT_DnrJ_EryC1 PF01041.12 XP_011277591.1 - 0.033 13.2 0.1 0.1 11.6 0.0 1.8 2 1 1 3 3 3 0 DegT/DnrJ/EryC1/StrS aminotransferase family GDC-P PF02347.11 XP_011277591.1 - 0.057 12.1 0.0 0.13 10.9 0.0 1.6 2 0 0 2 2 2 0 Glycine cleavage system P-protein Aminotran_5 PF00266.14 XP_011277591.1 - 0.069 11.8 0.0 0.15 10.7 0.0 1.5 1 0 0 1 1 1 0 Aminotransferase class-V APS_kinase PF01583.15 XP_011277592.1 - 1.6e-58 196.7 0.5 9.1e-57 191.1 0.0 2.0 1 1 1 2 2 2 2 Adenylylsulphate kinase AAA_33 PF13671.1 XP_011277592.1 - 0.035 13.9 0.0 0.063 13.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain Snf7 PF03357.16 XP_011277593.1 - 4e-26 91.4 12.9 4e-26 91.4 8.9 1.6 2 0 0 2 2 2 1 Snf7 Ist1 PF03398.9 XP_011277593.1 - 0.0039 16.6 0.2 0.0051 16.2 0.1 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway DUF3647 PF12363.3 XP_011277593.1 - 0.2 11.7 2.0 0.4 10.7 1.4 1.5 1 0 0 1 1 1 0 Phage protein DUF1002 PF06207.6 XP_011277593.1 - 0.3 10.3 4.5 0.26 10.5 2.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1002) SNARE PF05739.14 XP_011277594.1 - 2.8e-14 52.5 4.0 2.8e-14 52.5 2.8 2.2 2 0 0 2 2 2 1 SNARE domain Use1 PF09753.4 XP_011277594.1 - 0.0096 15.3 5.9 0.015 14.7 4.1 1.3 1 1 0 1 1 1 1 Membrane fusion protein Use1 DUF3753 PF12575.3 XP_011277594.1 - 0.045 13.5 4.2 0.14 11.9 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3753) Synaptobrevin PF00957.16 XP_011277594.1 - 0.11 12.1 0.1 0.11 12.1 0.1 3.4 4 0 0 4 4 4 0 Synaptobrevin GP41 PF00517.12 XP_011277594.1 - 0.37 10.3 4.3 0.25 10.8 1.5 1.8 2 1 0 2 2 2 0 Retroviral envelope protein NPV_P10 PF05531.7 XP_011277594.1 - 9.6 6.5 10.1 1.8 8.9 2.3 2.7 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF4452 PF14618.1 XP_011277595.1 - 0.003 17.3 3.9 0.0049 16.6 2.7 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4452) tRNA-synt_1c PF00749.16 XP_011277596.1 - 3.2e-110 367.7 0.0 4e-110 367.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain SMC_N PF02463.14 XP_011277597.1 - 2.1e-17 63.1 31.5 1.1e-16 60.7 21.9 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 XP_011277597.1 - 8.3e-11 42.5 35.9 8.3e-11 42.5 24.9 5.8 1 1 1 3 3 2 1 AAA domain Reo_sigmaC PF04582.7 XP_011277597.1 - 5e-05 22.6 12.0 0.00037 19.7 0.1 3.8 3 1 0 4 4 4 1 Reovirus sigma C capsid protein AAA_25 PF13481.1 XP_011277597.1 - 0.00014 21.3 0.0 0.0011 18.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 XP_011277597.1 - 0.00054 19.4 0.0 0.0011 18.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF4200 PF13863.1 XP_011277597.1 - 0.01 15.8 10.3 0.01 15.8 7.1 7.0 2 2 5 7 7 5 2 Domain of unknown function (DUF4200) AAA PF00004.24 XP_011277597.1 - 0.017 15.3 0.0 0.12 12.5 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NPV_P10 PF05531.7 XP_011277597.1 - 0.023 14.9 0.3 0.023 14.9 0.2 6.8 5 2 1 6 6 6 0 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.7 XP_011277597.1 - 0.068 12.9 54.8 0.033 13.9 7.4 7.1 2 2 2 6 6 6 0 Laminin Domain II DUF3407 PF11887.3 XP_011277597.1 - 0.1 11.8 6.2 0.27 10.5 0.6 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3407) CENP-F_leu_zip PF10473.4 XP_011277597.1 - 0.13 12.1 85.9 0.035 13.9 8.3 7.1 3 2 3 7 7 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_19 PF13245.1 XP_011277597.1 - 0.25 11.1 0.1 0.66 9.7 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_21 PF13304.1 XP_011277597.1 - 2.1 8.2 22.0 0.13 12.1 5.4 3.9 3 1 0 3 3 3 0 AAA domain DUF3722 PF12519.3 XP_011277599.1 - 6.3e-77 258.3 7.1 1.2e-76 257.4 4.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3722) MACPF PF01823.14 XP_011277599.1 - 0.0075 15.9 0.5 0.016 14.9 0.0 1.8 2 0 0 2 2 2 1 MAC/Perforin domain DUF2290 PF10053.4 XP_011277599.1 - 0.026 13.8 0.0 0.063 12.5 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2290) Spo7 PF03907.8 XP_011277600.1 - 1.1e-72 244.0 2.4 1.4e-72 243.6 1.7 1.1 1 0 0 1 1 1 1 Spo7-like protein Presenilin PF01080.12 XP_011277600.1 - 0.038 12.8 0.2 0.062 12.1 0.1 1.3 1 0 0 1 1 1 0 Presenilin COG4 PF08318.7 XP_011277601.1 - 9.5e-96 320.4 0.4 9.5e-96 320.4 0.2 2.1 2 0 0 2 2 2 1 COG4 transport protein zf-CCCH PF00642.19 XP_011277602.1 - 1e-18 66.5 26.7 0.00012 21.6 0.9 5.3 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Flavin_Reduct PF01613.13 XP_011277603.1 - 2.1e-21 76.3 0.0 2.9e-21 75.9 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain FUN14 PF04930.10 XP_011277604.1 - 8.2e-09 35.6 3.9 1.3e-07 31.8 1.1 3.0 2 2 1 3 3 3 1 FUN14 family DSPc PF00782.15 XP_011277605.1 - 0.003 17.1 0.8 0.15 11.6 0.6 2.8 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain TGS PF02824.16 XP_011277606.1 - 1.1e-22 79.5 0.0 2.3e-22 78.5 0.0 1.6 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 XP_011277606.1 - 2.7e-18 65.9 0.1 7.4e-18 64.6 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 XP_011277606.1 - 2e-09 36.8 0.1 4.7e-09 35.7 0.0 1.6 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 XP_011277606.1 - 0.00028 20.7 0.3 0.18 11.6 0.0 2.3 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 XP_011277606.1 - 0.0039 17.6 0.0 0.033 14.6 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein ArgK PF03308.11 XP_011277606.1 - 0.015 14.0 0.3 0.028 13.2 0.2 1.4 1 0 0 1 1 1 0 ArgK protein GTP_EFTU PF00009.22 XP_011277607.1 - 1.7e-32 112.4 0.0 8.7e-32 110.0 0.0 2.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 XP_011277607.1 - 9.9e-20 70.4 0.0 9.9e-20 70.4 0.0 2.6 3 0 0 3 3 3 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 XP_011277607.1 - 1.5e-12 47.4 2.7 4.1e-09 36.4 0.0 3.5 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 XP_011277607.1 - 2.4e-06 27.4 0.3 1.3e-05 25.0 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 XP_011277607.1 - 0.00038 20.9 0.5 0.0057 17.1 0.0 3.2 2 0 0 2 2 2 1 Miro-like protein ATP_bind_1 PF03029.12 XP_011277607.1 - 0.00063 19.3 0.0 0.002 17.7 0.0 1.9 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Dynamin_N PF00350.18 XP_011277607.1 - 0.0023 17.7 0.4 0.0023 17.7 0.3 3.9 3 1 0 4 4 4 1 Dynamin family AAA_22 PF13401.1 XP_011277607.1 - 0.007 16.5 0.2 0.088 12.9 0.2 2.9 1 1 0 1 1 1 1 AAA domain RNA_pol_Rpb1_5 PF04998.12 XP_011277608.1 - 8.4e-98 327.0 1.3 1.4e-97 326.3 0.2 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 XP_011277608.1 - 3.5e-64 215.7 0.1 9.2e-64 214.3 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 XP_011277608.1 - 2.6e-38 131.2 0.0 3e-37 127.7 0.0 2.9 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 XP_011277608.1 - 4.6e-24 84.2 3.2 2e-23 82.1 0.0 3.6 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_1 PF04997.7 XP_011277608.1 - 4.5e-23 82.0 0.7 4.5e-23 82.0 0.5 3.6 3 1 0 3 3 3 1 RNA polymerase Rpb1, domain 1 Daxx PF03344.10 XP_011277608.1 - 4.2 5.7 26.0 2.1 6.7 14.1 2.3 2 0 0 2 2 2 0 Daxx Family Nup96 PF12110.3 XP_011277609.1 - 1.8e-56 191.3 1.2 3e-56 190.6 0.8 1.4 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 XP_011277609.1 - 1.7e-45 154.3 0.9 6.3e-45 152.4 0.0 2.5 3 0 0 3 3 3 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 XP_011277609.1 - 5.9e-24 84.4 154.9 5.3e-11 42.7 33.9 5.2 2 1 3 5 5 5 4 Nucleoporin FG repeat region ParA PF10609.4 XP_011277610.1 - 1.7e-36 123.9 0.0 3.2e-36 123.0 0.0 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 XP_011277610.1 - 8.8e-16 57.8 0.0 1.4e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 XP_011277610.1 - 3.3e-06 27.1 0.0 1.7e-05 24.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain MipZ PF09140.6 XP_011277610.1 - 0.00016 20.8 0.0 0.00031 19.8 0.0 1.5 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.10 XP_011277610.1 - 0.00019 20.5 0.3 0.0057 15.7 0.0 2.5 2 1 1 3 3 3 1 Anion-transporting ATPase DUF258 PF03193.11 XP_011277610.1 - 0.007 15.5 0.0 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_26 PF13500.1 XP_011277610.1 - 0.015 14.8 0.0 0.24 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 XP_011277610.1 - 0.024 14.0 0.0 0.049 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Fer4_NifH PF00142.13 XP_011277610.1 - 0.048 12.8 0.0 0.67 9.0 0.0 2.3 2 1 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_29 PF13555.1 XP_011277610.1 - 0.089 12.3 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain TF_Zn_Ribbon PF08271.7 XP_011277610.1 - 0.19 11.0 0.1 0.19 11.0 0.1 1.9 2 0 0 2 2 2 0 TFIIB zinc-binding Zn_Tnp_IS1595 PF12760.2 XP_011277610.1 - 0.29 10.9 0.0 0.29 10.9 0.0 1.8 2 0 0 2 2 2 0 Transposase zinc-ribbon domain SNF2_N PF00176.18 XP_011277611.1 - 4.1e-83 278.6 0.5 6.6e-83 277.9 0.3 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 XP_011277611.1 - 1.3e-40 137.8 0.3 6.9e-40 135.4 0.2 2.4 1 0 0 1 1 1 1 SLIDE HAND PF09110.6 XP_011277611.1 - 3.6e-32 111.1 1.4 3.6e-32 111.1 1.0 2.9 2 0 0 2 2 2 1 HAND Helicase_C PF00271.26 XP_011277611.1 - 7.5e-16 57.7 0.0 2.4e-15 56.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 XP_011277611.1 - 2.4e-09 37.2 0.0 2.4e-09 37.2 0.0 3.3 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.24 XP_011277611.1 - 0.00019 20.9 0.0 0.00077 18.9 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Myb_DNA-binding PF00249.26 XP_011277611.1 - 0.0015 18.5 0.0 0.0083 16.1 0.0 2.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain DBINO PF13892.1 XP_011277611.1 - 0.0038 17.2 0.7 0.0038 17.2 0.5 3.5 4 0 0 4 4 4 1 DNA-binding domain AAA_14 PF13173.1 XP_011277611.1 - 0.004 17.0 0.3 0.051 13.4 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 XP_011277611.1 - 0.079 13.1 0.1 0.69 10.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain GSHPx PF00255.14 XP_011277612.1 - 1.5e-28 98.3 1.8 2.6e-28 97.5 1.2 1.4 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 XP_011277612.1 - 0.011 15.4 0.1 0.02 14.5 0.1 1.6 1 0 0 1 1 1 0 AhpC/TSA family Ribosomal_L21p PF00829.16 XP_011277612.1 - 0.021 14.9 0.9 0.038 14.1 0.3 1.7 1 1 0 1 1 1 0 Ribosomal prokaryotic L21 protein Poly_export PF02563.11 XP_011277612.1 - 0.034 13.9 0.0 4.4 7.1 0.0 2.6 1 1 0 2 2 2 0 Polysaccharide biosynthesis/export protein Redoxin PF08534.5 XP_011277612.1 - 0.084 12.4 0.0 0.16 11.4 0.0 1.6 1 1 0 1 1 1 0 Redoxin YvbH_ext PF11724.3 XP_011277612.1 - 0.52 10.0 3.6 0.5 10.0 0.5 2.4 3 0 0 3 3 3 0 YvbH-like oligomerisation region XPG_I PF00867.13 XP_011277613.1 - 7.1e-22 77.2 0.3 8.7e-21 73.7 0.0 2.6 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.12 XP_011277613.1 - 0.00087 19.5 0.1 0.0027 17.9 0.1 1.9 1 0 0 1 1 1 1 XPG N-terminal domain ApbA_C PF08546.6 XP_011277614.1 - 2.3e-29 101.9 0.1 4.6e-29 100.9 0.1 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 XP_011277614.1 - 2.1e-26 92.1 0.0 3e-26 91.6 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ThiF PF00899.16 XP_011277614.1 - 0.1 12.4 0.1 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 ThiF family HAD_2 PF13419.1 XP_011277616.1 - 4.3e-28 98.7 0.1 6.5e-28 98.1 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 XP_011277616.1 - 0.0011 18.6 0.0 0.002 17.7 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Zeta_toxin PF06414.7 XP_011277618.1 - 0.0003 19.9 1.5 0.00066 18.8 0.3 1.7 1 1 1 2 2 2 1 Zeta toxin DUF4228 PF14009.1 XP_011277618.1 - 2.5 8.1 8.0 4 7.5 5.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4228) ARF7EP_C PF14949.1 XP_011277618.1 - 4.9 7.6 6.3 4.6 7.7 1.9 2.0 2 0 0 2 2 2 0 ARF7 effector protein C-terminus Corona_nucleoca PF00937.13 XP_011277618.1 - 7 5.4 11.1 8.4 5.2 7.7 1.0 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DEAD PF00270.24 XP_011277619.1 - 3.2e-41 140.6 0.0 7.1e-41 139.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 XP_011277619.1 - 3e-20 71.8 0.1 1.2e-19 69.9 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 XP_011277619.1 - 0.0022 16.8 0.0 0.0036 16.1 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain vMSA PF00695.14 XP_011277619.1 - 7.7 5.6 6.7 12 4.9 4.6 1.2 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Pox_MCEL PF03291.11 XP_011277620.1 - 5.3e-94 314.7 0.0 7.1e-94 314.3 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_12 PF08242.7 XP_011277620.1 - 2.6e-10 40.6 0.5 1.2e-09 38.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 XP_011277620.1 - 1.1e-09 38.0 0.0 1.7e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 XP_011277620.1 - 2.3e-09 37.6 0.0 5.1e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 XP_011277620.1 - 4.2e-08 33.4 0.0 7.4e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 XP_011277620.1 - 6.6e-08 33.1 0.0 1.1e-07 32.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 XP_011277620.1 - 1.9e-05 24.4 0.0 3.8e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 XP_011277620.1 - 0.0042 16.4 0.0 0.0075 15.6 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW NNMT_PNMT_TEMT PF01234.12 XP_011277620.1 - 0.0069 15.3 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_4 PF02390.12 XP_011277620.1 - 0.03 13.3 0.0 0.082 11.9 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase DivIC PF04977.10 XP_011277620.1 - 6.9 6.2 8.8 14 5.2 6.1 1.5 1 0 0 1 1 1 0 Septum formation initiator AA_permease PF00324.16 XP_011277621.1 - 1.1e-55 188.9 35.7 1.3e-55 188.6 24.4 1.4 2 0 0 2 2 2 1 Amino acid permease La PF05383.12 XP_011277622.1 - 7e-18 64.1 1.2 1e-17 63.6 0.3 1.7 2 0 0 2 2 2 1 La domain SLD3 PF08639.5 XP_011277623.1 - 4.9e-50 170.6 29.4 4.9e-50 170.6 20.4 1.8 2 0 0 2 2 2 1 DNA replication regulator SLD3 DUF1546 PF07571.8 XP_011277624.1 - 3.2e-35 120.1 0.0 7.6e-35 118.9 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) TAF PF02969.12 XP_011277624.1 - 3.6e-27 94.0 0.5 8e-27 92.9 0.1 1.9 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) Histone PF00125.19 XP_011277624.1 - 1e-05 25.5 0.0 0.00011 22.2 0.0 2.3 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 XP_011277624.1 - 0.0029 17.6 0.4 0.009 16.0 0.0 2.0 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF445 PF04286.7 XP_011277624.1 - 0.012 15.1 2.4 0.074 12.5 0.2 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF445) Pkinase PF00069.20 XP_011277625.1 - 0.0033 16.5 0.1 0.0094 15.1 0.1 1.7 1 0 0 1 1 1 1 Protein kinase domain SNARE PF05739.14 XP_011277626.1 - 0.014 15.0 1.8 0.014 15.0 1.3 3.1 3 0 0 3 3 3 0 SNARE domain HLH PF00010.21 XP_011277627.1 - 2.5e-13 49.4 0.3 2.5e-13 49.4 0.2 3.2 1 1 2 3 3 3 2 Helix-loop-helix DNA-binding domain SPARC_Ca_bdg PF10591.4 XP_011277628.1 - 0.058 13.4 0.9 0.15 12.0 0.4 1.9 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF342 PF03961.8 XP_011277628.1 - 0.33 9.3 4.9 1.5 7.1 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DUF1451 PF07295.6 XP_011277629.1 - 0.13 12.0 1.3 0.24 11.1 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) TBPIP PF07106.8 XP_011277629.1 - 0.22 11.0 7.9 0.039 13.4 1.0 2.2 2 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) WD40 PF00400.27 XP_011277630.1 - 1.3e-21 75.6 18.8 2.1e-06 27.4 0.1 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat eIF2A PF08662.6 XP_011277630.1 - 5.4e-05 22.9 1.5 0.017 14.8 0.2 2.7 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A DUF3312 PF11768.3 XP_011277630.1 - 0.00049 18.4 0.0 0.38 8.9 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3312) IKI3 PF04762.7 XP_011277630.1 - 0.065 11.0 0.3 0.24 9.1 0.2 1.8 1 1 0 1 1 1 0 IKI3 family CBS PF00571.23 XP_011277631.1 - 8e-29 99.1 3.8 3.6e-14 52.2 0.1 4.4 4 1 0 4 4 4 4 CBS domain HTH_9 PF08221.6 XP_011277631.1 - 0.22 11.4 1.5 2 8.3 0.1 2.8 3 0 0 3 3 3 0 RNA polymerase III subunit RPC82 helix-turn-helix domain OPT PF03169.10 XP_011277632.1 - 4.3e-148 494.5 23.3 4.8e-148 494.3 16.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein BNIP3 PF06553.7 XP_011277632.1 - 0.53 9.6 5.2 0.88 8.9 3.6 1.3 1 0 0 1 1 1 0 BNIP3 HSDR_N PF04313.9 XP_011277633.1 - 1.5e-05 24.8 0.1 3.9e-05 23.4 0.1 1.7 1 0 0 1 1 1 1 Type I restriction enzyme R protein N terminus (HSDR_N) HSDR_N_2 PF13588.1 XP_011277633.1 - 0.0027 17.5 0.1 0.5 10.1 0.0 2.6 1 1 0 1 1 1 1 Type I restriction enzyme R protein N terminus (HSDR_N) Kdo PF06293.9 XP_011277633.1 - 0.063 12.3 0.1 0.12 11.3 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family BCNT PF07572.7 XP_011277634.1 - 1.4e-22 79.4 0.3 1.4e-22 79.4 0.2 2.7 2 0 0 2 2 2 1 Bucentaur or craniofacial development DUF2939 PF11159.3 XP_011277634.1 - 0.028 14.5 0.1 0.055 13.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) KH_1 PF00013.24 XP_011277635.1 - 3.2e-37 125.9 5.9 2.6e-13 49.3 0.6 3.3 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 XP_011277635.1 - 1.5e-25 88.2 10.9 1.1e-10 40.8 0.5 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 XP_011277635.1 - 5.5e-09 35.4 2.7 0.024 14.1 0.2 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 XP_011277635.1 - 0.00038 20.0 0.6 2.8 7.6 0.0 3.6 3 1 0 3 3 3 2 KH domain KH_5 PF13184.1 XP_011277635.1 - 0.47 10.2 2.7 4.5 7.1 0.1 3.1 3 0 0 3 3 3 0 NusA-like KH domain DNA_pol_phi PF04931.8 XP_011277636.1 - 8.3e-76 255.3 73.9 2.1e-51 174.6 37.3 3.7 2 1 1 3 3 3 2 DNA polymerase phi ABC_membrane PF00664.18 XP_011277637.1 - 3.7e-46 157.7 9.1 4.8e-46 157.3 6.3 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 XP_011277637.1 - 1.5e-32 112.7 2.7 1.8e-32 112.5 0.0 2.5 3 0 0 3 3 3 1 ABC transporter SMC_N PF02463.14 XP_011277637.1 - 4.3e-05 22.8 1.0 0.0016 17.6 0.0 2.5 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 XP_011277637.1 - 0.0015 18.5 0.4 0.0086 16.0 0.3 2.1 1 1 0 1 1 1 1 AAA ATPase domain DEAD PF00270.24 XP_011277637.1 - 0.0022 17.5 0.1 0.0065 15.9 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase IstB_IS21 PF01695.12 XP_011277637.1 - 0.0029 17.0 0.3 0.067 12.6 0.0 2.9 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_17 PF13207.1 XP_011277637.1 - 0.0039 18.0 0.4 0.013 16.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 XP_011277637.1 - 0.0046 16.6 0.2 0.21 11.3 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) MTS_N PF08468.6 XP_011277637.1 - 0.009 15.8 0.6 7.3 6.4 0.0 4.0 4 1 0 4 4 4 1 Methyltransferase small domain N-terminal AAA_29 PF13555.1 XP_011277637.1 - 0.0094 15.4 0.0 0.022 14.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 XP_011277637.1 - 0.014 14.6 0.0 0.033 13.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ABC_ATPase PF09818.4 XP_011277637.1 - 0.025 13.2 0.1 0.055 12.0 0.0 1.5 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA PF00004.24 XP_011277637.1 - 0.037 14.2 0.4 0.4 10.8 0.3 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF3987 PF13148.1 XP_011277637.1 - 0.061 11.8 0.0 0.1 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) AAA_22 PF13401.1 XP_011277637.1 - 0.075 13.1 0.5 0.87 9.7 0.3 2.3 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 XP_011277637.1 - 0.13 11.6 0.0 0.28 10.6 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_25 PF13481.1 XP_011277637.1 - 0.14 11.4 0.0 0.86 8.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain KAR9 PF08580.5 XP_011277638.1 - 1.1e-71 242.1 35.0 1.5e-71 241.6 24.3 1.1 1 0 0 1 1 1 1 Yeast cortical protein KAR9 CENP-F_leu_zip PF10473.4 XP_011277638.1 - 0.0091 15.8 3.3 0.0091 15.8 2.3 2.2 2 1 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Occludin_ELL PF07303.8 XP_011277638.1 - 0.8 10.4 5.7 0.36 11.5 0.4 3.1 3 1 0 3 3 3 0 Occludin homology domain RrnaAD PF00398.15 XP_011277639.1 - 5.7e-64 215.6 0.0 6.7e-64 215.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 XP_011277639.1 - 2.7e-09 37.0 0.0 4.1e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 XP_011277639.1 - 7e-05 23.3 0.0 0.00013 22.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 XP_011277639.1 - 0.00019 21.0 0.0 0.00033 20.2 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein PCMT PF01135.14 XP_011277639.1 - 0.0031 17.0 0.0 0.0051 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 XP_011277639.1 - 0.004 16.5 0.0 0.0078 15.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 XP_011277639.1 - 0.0057 15.7 0.0 0.01 14.9 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 XP_011277639.1 - 0.025 14.2 0.0 0.043 13.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 XP_011277639.1 - 0.034 13.7 0.0 0.071 12.6 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain DREV PF05219.7 XP_011277639.1 - 0.046 12.5 0.0 0.074 11.9 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Ubie_methyltran PF01209.13 XP_011277639.1 - 0.093 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.13 XP_011277639.1 - 0.14 11.3 0.0 0.26 10.4 0.0 1.5 2 0 0 2 2 2 0 O-methyltransferase Kelch_3 PF13415.1 XP_011277640.1 - 9.7e-35 117.9 3.6 2.1e-08 34.1 0.0 7.1 7 0 0 7 7 7 4 Galactose oxidase, central domain DUF4110 PF13422.1 XP_011277640.1 - 2.6e-28 97.7 1.1 2.6e-28 97.7 0.7 4.8 5 1 1 6 6 6 1 Domain of unknown function (DUF4110) Kelch_4 PF13418.1 XP_011277640.1 - 2.8e-26 91.0 17.3 6.9e-05 22.5 0.0 7.4 5 3 1 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.1 XP_011277640.1 - 2.5e-20 71.6 7.6 0.00057 19.9 0.2 6.3 5 1 1 6 6 6 5 Kelch motif Kelch_5 PF13854.1 XP_011277640.1 - 2.8e-15 55.8 3.9 0.032 14.1 0.1 6.3 6 1 0 6 6 6 4 Kelch motif Kelch_2 PF07646.10 XP_011277640.1 - 8.4e-12 44.3 9.6 0.00071 19.2 0.0 6.0 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.20 XP_011277640.1 - 5.5e-09 35.4 8.4 0.15 11.6 0.0 5.8 6 0 0 6 6 6 3 Kelch motif PGM_PMM_I PF02878.11 XP_011277641.1 - 2e-20 72.6 0.1 1.6e-09 37.3 0.0 2.7 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.15 XP_011277641.1 - 2.7e-11 43.3 0.1 6.6e-11 42.0 0.1 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.11 XP_011277641.1 - 9.6e-10 38.7 0.1 5e-09 36.4 0.0 2.2 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 XP_011277641.1 - 0.0042 17.1 0.0 0.0086 16.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III Mitochondr_Som1 PF11093.3 XP_011277642.1 - 9.7e-23 79.7 0.6 1.8e-22 78.9 0.4 1.4 1 0 0 1 1 1 1 Mitochondrial export protein Som1 DUF3818 PF12825.2 XP_011277643.1 - 7.9e-113 376.5 25.4 7.9e-113 376.5 17.6 2.3 2 0 0 2 2 2 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 XP_011277643.1 - 1.8e-43 147.4 2.4 2.2e-43 147.1 0.2 2.3 2 0 0 2 2 2 1 PX-associated PX PF00787.19 XP_011277643.1 - 2.7e-15 56.1 6.8 1.6e-13 50.4 1.5 4.2 2 1 0 2 2 2 1 PX domain PBP1_TM PF14812.1 XP_011277643.1 - 6.9 7.0 12.6 11 6.4 2.9 3.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal HAMP PF00672.20 XP_011277644.1 - 3.3e-39 132.9 8.1 3.3e-09 36.7 0.0 5.7 5 0 0 5 5 5 5 HAMP domain HATPase_c PF02518.21 XP_011277644.1 - 3.2e-30 104.0 0.3 1.1e-29 102.3 0.2 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 XP_011277644.1 - 1.2e-25 89.6 0.6 6.4e-25 87.3 0.1 2.4 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 XP_011277644.1 - 9.6e-15 54.3 0.1 4.4e-14 52.2 0.1 2.3 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain DUF2365 PF10157.4 XP_011277644.1 - 8.7 6.2 19.1 5.3 6.9 0.0 6.1 3 1 2 7 7 7 0 Uncharacterized conserved protein (DUF2365) Cullin_Nedd8 PF10557.4 XP_011277645.1 - 0.069 12.9 0.2 0.19 11.6 0.1 1.7 1 0 0 1 1 1 0 Cullin protein neddylation domain Mito_carr PF00153.22 XP_011277646.1 - 2.5e-72 238.6 2.0 1e-24 86.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L37ae PF01780.14 XP_011277647.1 - 8.2e-35 118.5 3.9 1.1e-34 118.2 2.7 1.1 1 0 0 1 1 1 1 Ribosomal L37ae protein family Rep_fac-A_C PF08646.5 XP_011277647.1 - 0.0074 16.0 0.5 0.0095 15.6 0.4 1.3 1 0 0 1 1 1 1 Replication factor-A C terminal domain Zn_Tnp_IS1595 PF12760.2 XP_011277647.1 - 0.02 14.7 4.4 0.037 13.8 3.0 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain DUF1364 PF07102.7 XP_011277647.1 - 0.029 14.2 1.0 0.043 13.6 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1364) OrfB_Zn_ribbon PF07282.6 XP_011277647.1 - 0.048 13.3 2.6 0.091 12.4 1.8 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Lar_restr_allev PF14354.1 XP_011277647.1 - 0.053 13.8 0.2 0.098 12.9 0.2 1.5 1 0 0 1 1 1 0 Restriction alleviation protein Lar CarbpepA_inh PF02977.10 XP_011277647.1 - 0.056 13.0 2.3 0.22 11.1 0.2 2.2 1 1 1 2 2 2 0 Carboxypeptidase A inhibitor Elf1 PF05129.8 XP_011277647.1 - 0.11 12.2 2.9 0.2 11.3 2.0 1.5 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-H2C2_2 PF13465.1 XP_011277647.1 - 0.12 12.7 0.6 1.7 9.1 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger double domain Endonuclease_7 PF02945.10 XP_011277647.1 - 0.14 11.8 1.4 0.2 11.3 1.0 1.4 1 1 0 1 1 1 0 Recombination endonuclease VII zf-NADH-PPase PF09297.6 XP_011277647.1 - 0.17 11.4 2.1 0.32 10.5 1.5 1.5 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain zf-C4_ClpX PF06689.8 XP_011277647.1 - 0.19 11.3 0.3 0.19 11.3 0.2 2.1 2 0 0 2 2 2 0 ClpX C4-type zinc finger SCA7 PF08313.7 XP_011277649.1 - 0.00081 18.9 0.3 0.0024 17.4 0.1 1.9 2 0 0 2 2 2 1 SCA7, zinc-binding domain RNA_pol_Rpo13 PF12136.3 XP_011277649.1 - 0.087 12.5 0.2 0.17 11.5 0.1 1.5 1 0 0 1 1 1 0 RNA polymerase Rpo13 subunit HTH domain GAGA PF09237.6 XP_011277649.1 - 0.098 12.2 0.6 0.21 11.2 0.4 1.6 1 0 0 1 1 1 0 GAGA factor Fip1 PF05182.8 XP_011277650.1 - 8.8e-22 76.1 0.5 1.5e-21 75.3 0.4 1.4 1 0 0 1 1 1 1 Fip1 motif Nop14 PF04147.7 XP_011277650.1 - 0.19 9.6 32.1 0.25 9.2 22.3 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 XP_011277650.1 - 2.4 6.5 27.8 3.4 6.0 19.2 1.2 1 0 0 1 1 1 0 Daxx Family DUF2457 PF10446.4 XP_011277650.1 - 2.9 6.5 29.0 5.6 5.5 20.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Sporozoite_P67 PF05642.6 XP_011277650.1 - 5.8 4.6 14.9 7.8 4.2 10.3 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PH PF00169.24 XP_011277651.1 - 5.2e-08 33.0 0.4 5.2e-08 33.0 0.3 3.2 3 0 0 3 3 3 1 PH domain PUF PF00806.14 XP_011277652.1 - 1.3e-28 96.8 0.2 2e-06 26.9 0.0 7.2 7 0 0 7 7 7 5 Pumilio-family RNA binding repeat RRM_5 PF13893.1 XP_011277652.1 - 1.3e-07 31.3 0.0 3e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 XP_011277652.1 - 4e-07 29.9 0.0 8.7e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 XP_011277652.1 - 7.9e-07 28.6 0.0 1.6e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LRR_8 PF13855.1 XP_011277653.1 - 2.1e-10 40.2 10.6 0.0027 17.3 0.5 6.1 4 1 2 6 6 6 3 Leucine rich repeat F-box-like PF12937.2 XP_011277653.1 - 4.1e-10 39.2 2.7 1.5e-09 37.3 1.9 2.1 1 0 0 1 1 1 1 F-box-like LRR_1 PF00560.28 XP_011277653.1 - 0.00012 21.5 27.9 2.1 8.7 0.1 10.3 9 3 0 9 9 9 2 Leucine Rich Repeat LcrV PF04792.7 XP_011277653.1 - 0.0079 15.2 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 V antigen (LcrV) protein LRR_6 PF13516.1 XP_011277653.1 - 0.01 15.8 24.9 40 4.7 0.0 11.0 12 2 0 12 12 12 0 Leucine Rich repeat F-box-like_2 PF13013.1 XP_011277653.1 - 0.032 13.9 0.9 0.25 11.0 0.1 2.5 2 0 0 2 2 2 0 F-box-like domain Adeno_E4_34 PF04528.8 XP_011277653.1 - 0.4 10.2 9.9 0.048 13.2 0.6 3.2 2 2 2 4 4 4 0 Adenovirus early E4 34 kDa protein conserved region F-box PF00646.28 XP_011277653.1 - 2 8.1 11.5 0.12 12.1 1.3 3.6 3 0 0 3 3 3 0 F-box domain LRR_7 PF13504.1 XP_011277653.1 - 4.3 7.9 13.7 73 4.2 0.2 7.5 7 1 0 7 7 7 0 Leucine rich repeat BIR PF00653.16 XP_011277654.1 - 1.2e-28 99.3 5.7 2.6e-14 53.3 0.6 2.6 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain SE PF08491.5 XP_011277655.1 - 6.2e-105 349.9 0.0 7.7e-105 349.6 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.14 XP_011277655.1 - 6.3e-15 55.0 0.0 1.1e-14 54.3 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 XP_011277655.1 - 2.4e-09 36.5 0.1 2.3e-05 23.4 0.1 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.17 XP_011277655.1 - 0.00032 19.6 0.4 0.54 9.0 0.0 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A 3HCDH_N PF02737.13 XP_011277655.1 - 0.0011 18.6 0.2 0.0022 17.6 0.1 1.5 2 0 0 2 2 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 XP_011277655.1 - 0.0013 17.6 1.0 0.072 11.9 0.6 2.4 2 0 0 2 2 2 1 FAD binding domain ApbA PF02558.11 XP_011277655.1 - 0.0019 17.6 0.1 0.0034 16.8 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_8 PF13450.1 XP_011277655.1 - 0.0021 18.0 0.2 0.006 16.5 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 XP_011277655.1 - 0.0028 17.5 0.0 0.0048 16.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.18 XP_011277655.1 - 0.013 15.2 0.0 0.13 12.0 0.0 2.2 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox PF00070.22 XP_011277655.1 - 0.017 15.4 0.5 0.14 12.5 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 XP_011277655.1 - 0.03 13.4 1.4 0.077 12.0 0.8 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase Trp_halogenase PF04820.9 XP_011277655.1 - 0.05 12.2 0.4 0.52 8.8 0.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase F420_oxidored PF03807.12 XP_011277655.1 - 0.056 13.8 0.1 0.12 12.7 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 XP_011277655.1 - 0.057 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short PF00106.20 XP_011277655.1 - 0.083 12.7 0.9 0.43 10.4 0.2 2.1 2 0 0 2 2 2 0 short chain dehydrogenase HI0933_like PF03486.9 XP_011277655.1 - 0.093 11.1 0.0 0.17 10.3 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.1 XP_011277655.1 - 0.097 12.7 0.1 0.33 11.0 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 XP_011277655.1 - 0.15 11.8 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 ThiF family CBP4 PF07960.6 XP_011277656.1 - 1.4e-43 147.5 4.7 1.7e-43 147.2 3.2 1.0 1 0 0 1 1 1 1 CBP4 CCDC74_C PF14917.1 XP_011277656.1 - 0.24 11.4 4.5 0.41 10.7 3.1 1.3 1 0 0 1 1 1 0 Coiled coil protein 74, C terminal Tup_N PF08581.5 XP_011277656.1 - 0.86 9.8 13.3 0.13 12.4 5.7 2.0 2 0 0 2 2 2 0 Tup N-terminal DUF972 PF06156.8 XP_011277656.1 - 1.3 9.3 7.3 0.24 11.7 2.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF972) AAA_23 PF13476.1 XP_011277656.1 - 4.3 7.6 9.9 5.7 7.2 6.9 1.2 1 0 0 1 1 1 0 AAA domain UBN2 PF14223.1 XP_011277657.1 - 0.0012 18.6 0.6 0.0039 16.9 0.0 2.0 2 2 0 2 2 2 1 gag-polypeptide of LTR copia-type DUF2465 PF10239.4 XP_011277657.1 - 0.023 13.9 0.3 0.05 12.8 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2465) DUF2935 PF11155.3 XP_011277657.1 - 0.034 14.2 0.2 0.1 12.6 0.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) Fib_alpha PF08702.5 XP_011277657.1 - 0.043 13.9 0.7 0.087 12.9 0.1 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Snapin_Pallidin PF14712.1 XP_011277657.1 - 0.051 13.8 0.4 0.29 11.4 0.0 2.1 2 0 0 2 2 2 0 Snapin/Pallidin Hemerythrin PF01814.18 XP_011277657.1 - 0.061 13.4 0.1 0.71 10.0 0.0 2.4 2 1 0 2 2 2 0 Hemerythrin HHE cation binding domain Ribonuc_L-PSP PF01042.16 XP_011277658.1 - 7.9e-24 83.7 0.0 9.3e-24 83.5 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Dna2 PF08696.6 XP_011277659.1 - 9.2e-58 194.9 0.2 1.2e-56 191.3 0.0 2.5 2 0 0 2 2 2 1 DNA replication factor Dna2 AAA_12 PF13087.1 XP_011277659.1 - 3.4e-51 173.4 0.2 9.3e-51 172.0 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 XP_011277659.1 - 6.3e-33 114.3 11.1 2.2e-32 112.5 0.0 3.6 2 2 0 2 2 1 1 AAA domain AAA_30 PF13604.1 XP_011277659.1 - 2.9e-11 43.3 0.0 3.4e-09 36.5 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 XP_011277659.1 - 3.7e-08 33.0 0.0 8.5e-08 31.8 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain Cas_Cas4 PF01930.12 XP_011277659.1 - 2e-06 27.8 0.1 6.6e-06 26.1 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function DUF83 Viral_helicase1 PF01443.13 XP_011277659.1 - 2.9e-05 23.7 2.8 0.17 11.3 0.0 3.9 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase SRP54 PF00448.17 XP_011277659.1 - 0.00041 19.8 0.1 0.0011 18.5 0.1 1.7 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_16 PF13191.1 XP_011277659.1 - 0.0029 17.6 0.0 0.0085 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Helicase_RecD PF05127.9 XP_011277659.1 - 0.0036 16.9 0.0 0.015 14.9 0.0 2.1 1 0 0 1 1 1 1 Helicase AAA_22 PF13401.1 XP_011277659.1 - 0.0045 17.1 0.1 0.41 10.7 0.0 3.1 3 0 0 3 3 2 1 AAA domain MobB PF03205.9 XP_011277659.1 - 0.0065 16.1 0.6 0.026 14.2 0.0 2.2 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B DUF911 PF06023.7 XP_011277659.1 - 0.0074 15.5 0.0 0.017 14.3 0.0 1.5 1 0 0 1 1 1 1 Archaeal protein of unknown function (DUF911) UvrD_C_2 PF13538.1 XP_011277659.1 - 0.0079 16.3 0.2 0.031 14.4 0.0 2.2 2 0 0 2 2 1 1 UvrD-like helicase C-terminal domain AAA_5 PF07728.9 XP_011277659.1 - 0.014 15.0 0.1 0.045 13.4 0.1 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) CbiA PF01656.18 XP_011277659.1 - 0.026 13.9 0.0 0.097 12.0 0.0 2.0 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA PF00004.24 XP_011277659.1 - 0.027 14.6 1.0 0.26 11.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 XP_011277659.1 - 0.041 13.7 0.0 0.12 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 XP_011277659.1 - 0.048 13.1 0.0 0.12 11.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.1 XP_011277659.1 - 0.1 11.9 0.0 0.31 10.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain Aldolase_II PF00596.16 XP_011277660.1 - 1.2e-43 148.8 0.0 1.4e-43 148.6 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain RLL PF10036.4 XP_011277660.1 - 0.012 15.0 0.7 0.18 11.1 0.5 2.2 1 1 0 1 1 1 0 Putative carnitine deficiency-associated protein LSM PF01423.17 XP_011277661.1 - 3e-11 42.7 0.2 4.3e-11 42.2 0.2 1.3 1 0 0 1 1 1 1 LSM domain IF-2 PF11987.3 XP_011277662.1 - 0.036 13.9 0.0 0.041 13.7 0.0 1.1 1 0 0 1 1 1 0 Translation-initiation factor 2 OST3_OST6 PF04756.8 XP_011277663.1 - 5.3e-23 81.3 9.5 9e-23 80.5 6.6 1.3 1 0 0 1 1 1 1 OST3 / OST6 family Thioredoxin PF00085.15 XP_011277663.1 - 0.00018 21.1 0.0 0.00053 19.6 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin DUF4239 PF14023.1 XP_011277663.1 - 0.061 12.6 3.8 0.21 10.9 1.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) Cation_ATPase_C PF00689.16 XP_011277663.1 - 0.26 10.7 12.9 0.56 9.7 0.1 2.5 3 0 0 3 3 3 0 Cation transporting ATPase, C-terminus DUF3377 PF11857.3 XP_011277663.1 - 0.56 9.8 3.3 0.62 9.7 0.9 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF3377) AA_permease PF00324.16 XP_011277663.1 - 1.6 6.9 16.6 14 3.8 11.5 2.0 1 1 0 1 1 1 0 Amino acid permease ABC2_membrane_5 PF13346.1 XP_011277663.1 - 2.1 7.6 22.3 3.1 7.0 5.8 3.1 3 0 0 3 3 3 0 ABC-2 family transporter protein DUF3816 PF12822.2 XP_011277663.1 - 3.6 7.4 18.6 2.1 8.2 11.1 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3816) MKT1_C PF12246.3 XP_011277664.1 - 9.6e-44 149.1 3.1 1.6e-43 148.4 2.2 1.4 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 XP_011277664.1 - 1.2e-27 96.0 1.4 5.5e-27 93.9 0.2 2.6 3 0 0 3 3 3 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.12 XP_011277664.1 - 7.7e-12 45.3 0.0 2.5e-11 43.7 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 XP_011277664.1 - 1e-07 31.9 0.0 2.6e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 XPG I-region SNF2_N PF00176.18 XP_011277665.1 - 1.5e-69 234.1 1.2 2.3e-69 233.4 0.8 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 XP_011277665.1 - 1.1e-12 47.6 0.0 3.5e-12 46.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 XP_011277665.1 - 1.4e-07 31.1 0.0 4.1e-07 29.6 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase E1-E2_ATPase PF00122.15 XP_011277666.1 - 1.6e-19 69.8 0.0 3.5e-19 68.7 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 XP_011277666.1 - 5.9e-17 62.8 0.0 5.9e-16 59.5 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 XP_011277666.1 - 5.1e-12 45.5 0.0 1.6e-11 44.0 0.0 1.9 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 XP_011277666.1 - 2e-10 41.1 5.1 1.9e-09 37.9 3.5 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 XP_011277666.1 - 0.0091 15.5 0.3 0.0091 15.5 0.2 3.5 4 0 0 4 4 4 1 haloacid dehalogenase-like hydrolase Spore_III_AF PF09581.5 XP_011277666.1 - 0.11 12.4 0.0 0.11 12.4 0.0 2.9 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) Homeobox PF00046.24 XP_011277667.1 - 5.7e-17 61.0 1.8 1.2e-16 60.0 1.2 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 XP_011277667.1 - 0.012 15.2 0.9 0.039 13.6 0.6 1.9 1 0 0 1 1 1 0 Homeobox KN domain YL1 PF05764.8 XP_011277667.1 - 2 7.9 11.9 0.053 13.1 3.9 1.5 2 0 0 2 2 2 0 YL1 nuclear protein SPRY PF00622.23 XP_011277668.1 - 2.2e-18 66.5 0.0 4.5e-18 65.5 0.0 1.6 1 0 0 1 1 1 1 SPRY domain HECT PF00632.20 XP_011277669.1 - 4.4e-79 265.9 5.2 4.4e-79 265.9 3.6 1.9 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) IQ PF00612.22 XP_011277669.1 - 0.021 14.4 0.3 0.043 13.4 0.2 1.6 1 0 0 1 1 1 0 IQ calmodulin-binding motif Cyclin_N PF00134.18 XP_011277670.1 - 5.3e-44 148.8 0.1 1.2e-43 147.6 0.1 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 XP_011277670.1 - 2.6e-32 111.2 0.4 5.7e-32 110.1 0.0 1.8 2 0 0 2 2 2 1 Cyclin, C-terminal domain MAM33 PF02330.11 XP_011277671.1 - 8.1e-23 81.2 10.5 1.3e-22 80.5 7.3 1.3 1 0 0 1 1 1 1 Mitochondrial glycoprotein Ubiq_cyt_C_chap PF03981.7 XP_011277671.1 - 0.071 12.9 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Ubiquinol-cytochrome C chaperone SBP_bac_3 PF00497.15 XP_011277671.1 - 0.088 12.0 0.7 0.13 11.5 0.5 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 Ribosomal_60s PF00428.14 XP_011277672.1 - 4.1e-25 87.9 12.1 4.9e-25 87.7 8.4 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Sigma70_ner PF04546.8 XP_011277672.1 - 0.022 14.3 0.6 0.027 14.1 0.4 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region MTTB PF06253.6 XP_011277672.1 - 0.49 8.0 0.0 0.49 8.0 0.0 1.9 1 1 1 2 2 2 0 Trimethylamine methyltransferase (MTTB) VIT1 PF01988.14 XP_011277672.1 - 6.8 6.1 8.3 0.99 8.8 0.8 2.0 2 0 0 2 2 2 0 VIT family Ribosomal_L13e PF01294.13 XP_011277673.1 - 4.2e-63 212.0 6.7 6.5e-63 211.4 4.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e 4HBT_3 PF13622.1 XP_011277673.1 - 0.078 12.7 2.6 0.57 9.8 1.8 2.1 1 1 0 1 1 1 0 Thioesterase-like superfamily MFS_1 PF07690.11 XP_011277674.1 - 2.2e-38 131.8 39.6 6.9e-38 130.2 27.0 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 XP_011277674.1 - 4.9e-16 58.3 7.0 4.9e-16 58.3 4.8 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter DUF2975 PF11188.3 XP_011277674.1 - 0.66 9.6 24.0 0.32 10.6 3.1 4.3 1 1 2 4 4 4 0 Protein of unknown function (DUF2975) Enolase_C PF00113.17 XP_011277675.1 - 2.8e-152 505.8 0.0 4.4e-152 505.1 0.0 1.3 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 XP_011277675.1 - 7.6e-58 194.1 0.1 1.2e-57 193.5 0.0 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE PF01188.16 XP_011277675.1 - 0.0086 16.5 0.0 0.024 15.1 0.0 1.8 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain DUF4150 PF13665.1 XP_011277675.1 - 0.022 14.6 0.2 3.9 7.4 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4150) MR_MLE_C PF13378.1 XP_011277675.1 - 0.085 12.8 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 Enolase C-terminal domain-like MAAL_C PF07476.6 XP_011277675.1 - 0.092 11.6 0.1 0.21 10.4 0.0 1.6 2 0 0 2 2 2 0 Methylaspartate ammonia-lyase C-terminus