# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Myosin_head PF00063.21 CRJ79371.1 - 1.5e-269 895.9 0.0 2.8e-269 895.0 0.0 1.5 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_N PF02736.19 CRJ79371.1 - 3e-12 46.2 0.2 6.4e-12 45.1 0.2 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 CRJ79371.1 - 0.046 14.0 0.0 0.046 14.0 0.0 4.0 5 0 0 5 5 5 0 AAA domain TsaE PF02367.17 CRJ79371.1 - 0.086 12.8 0.0 0.28 11.2 0.0 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IL32 PF15225.6 CRJ79371.1 - 3.6 8.0 5.8 17 5.8 2.4 3.5 2 0 0 2 2 2 0 Interleukin 32 Myosin_tail_1 PF01576.19 CRJ79371.1 - 9.8 3.8 158.6 0.0075 14.1 38.7 2.7 1 1 2 3 3 3 0 Myosin tail Annexin PF00191.20 CRJ79379.1 - 1.2e-19 70.1 1.8 0.00013 21.9 0.0 4.4 4 0 0 4 4 4 4 Annexin Acetyltransf_11 PF13720.6 CRJ79379.1 - 0.069 13.6 0.5 5.1 7.6 0.0 3.1 3 0 0 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 GPI2 PF06432.11 CRJ79388.1 - 2.8e-128 427.2 1.9 3.4e-128 427.0 1.9 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Ribosomal_L22 PF00237.19 CRJ79392.1 - 0.0068 16.6 0.0 7.8 6.8 0.0 2.6 2 0 0 2 2 2 2 Ribosomal protein L22p/L17e BatA PF07584.11 CRJ79392.1 - 1.5 9.2 3.2 51 4.3 0.6 2.8 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal CFEM PF05730.11 CRJ79401.1 - 5.5e-10 39.2 7.1 8.4e-10 38.6 7.1 1.3 1 0 0 1 1 1 1 CFEM domain Metallophos_2 PF12850.7 CRJ79405.1 - 3.6e-11 43.5 0.0 2.2e-09 37.7 0.0 2.6 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 CRJ79405.1 - 1.7e-08 35.2 0.0 3.8e-08 34.1 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase EF-1_beta_acid PF10587.9 CRJ79405.1 - 5.7 7.5 9.6 13 6.3 9.6 1.6 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region Med31 PF05669.12 CRJ79409.1 - 1.4e-36 124.4 0.7 1.6e-36 124.2 0.7 1.0 1 0 0 1 1 1 1 SOH1 TFIIS_C PF01096.18 CRJ79413.1 - 1.5e-20 72.7 2.4 2.7e-20 71.9 2.4 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Metallophos_2 PF12850.7 CRJ79413.1 - 0.0081 16.4 0.0 0.01 16.0 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 CRJ79413.1 - 0.061 13.8 0.0 0.076 13.5 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase Med31 PF05669.12 CRJ79418.1 - 1.4e-36 124.4 0.7 1.6e-36 124.2 0.7 1.0 1 0 0 1 1 1 1 SOH1 Thaumatin PF00314.17 CRJ79422.1 - 1.5e-66 224.1 2.9 5.3e-41 140.6 0.1 2.5 2 0 0 2 2 2 2 Thaumatin family TFIIS_C PF01096.18 CRJ79422.1 - 1.6e-19 69.4 2.4 1.6e-19 69.4 2.4 2.3 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 CRJ79422.1 - 2.1e-05 24.3 1.3 3.8e-05 23.5 0.1 2.1 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 CRJ79422.1 - 0.0051 16.8 3.0 0.051 13.6 0.1 2.7 2 0 0 2 2 2 1 Transposase zinc-ribbon domain PG_binding_3 PF09374.10 CRJ79422.1 - 0.024 14.9 0.0 2.5 8.4 0.0 2.3 2 0 0 2 2 2 0 Predicted Peptidoglycan domain Glyco_hydro_64 PF16483.5 CRJ79422.1 - 0.072 12.4 0.1 1.5 8.0 0.0 2.2 2 0 0 2 2 2 0 Beta-1,3-glucanase IBR PF01485.21 CRJ79422.1 - 8.2 6.7 11.2 6.1 7.1 0.1 3.6 4 0 0 4 4 4 0 IBR domain, a half RING-finger domain Ank_4 PF13637.6 CRJ79426.1 - 3e-07 30.9 0.0 0.0002 21.8 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CRJ79426.1 - 8e-07 29.6 0.0 8.6e-06 26.3 0.0 2.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CRJ79426.1 - 1.4e-06 28.1 0.8 0.06 13.9 0.1 4.1 4 2 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 CRJ79426.1 - 2.1e-06 27.9 0.0 0.2 12.0 0.0 4.1 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 CRJ79426.1 - 0.00047 20.5 0.0 6.9 7.3 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat MFS_5 PF05631.14 CRJ79431.1 - 6.7e-56 189.7 1.9 9.5e-56 189.2 1.9 1.1 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 CRJ79431.1 - 2.7e-12 46.3 11.7 3.8e-12 45.8 11.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Ank_5 PF13857.6 CRJ79431.1 - 2.6e-07 30.8 0.0 0.68 10.3 0.0 5.1 4 1 1 5 5 5 1 Ankyrin repeats (many copies) Sugar_tr PF00083.24 CRJ79431.1 - 2.7e-07 29.8 1.1 3.6e-07 29.4 1.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Ank_3 PF13606.6 CRJ79431.1 - 1.5e-06 28.0 0.0 0.21 12.3 0.1 4.2 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 CRJ79431.1 - 1.8e-06 28.4 0.0 0.0018 18.8 0.0 4.0 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CRJ79431.1 - 5.3e-06 26.9 0.0 3.1e-05 24.5 0.0 2.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) MFS_4 PF06779.14 CRJ79431.1 - 0.00034 20.0 7.1 0.00053 19.4 7.1 1.2 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Ank PF00023.30 CRJ79431.1 - 0.0043 17.4 0.0 12 6.6 0.0 4.0 5 0 0 5 5 4 1 Ankyrin repeat Nha1_C PF08619.10 CRJ79431.1 - 0.052 12.8 0.5 0.073 12.3 0.5 1.1 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus MFS_2 PF13347.6 CRJ79431.1 - 0.11 11.0 7.3 0.55 8.7 7.5 1.8 1 1 1 2 2 2 0 MFS/sugar transport protein HSP70 PF00012.20 CRJ79440.1 - 9.2e-11 40.6 0.3 1.3e-09 36.8 0.1 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 CRJ79440.1 - 0.0082 15.0 0.1 0.042 12.6 0.0 1.9 2 0 0 2 2 2 1 MreB/Mbl protein MFS_5 PF05631.14 CRJ79445.1 - 8.6e-50 169.6 2.4 1.1e-49 169.2 2.4 1.1 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 CRJ79445.1 - 1.1e-09 37.7 13.5 2e-09 36.8 13.5 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CRJ79445.1 - 9.7e-08 31.3 0.8 1.3e-07 30.9 0.8 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 CRJ79445.1 - 0.00022 20.7 7.9 0.00031 20.2 7.9 1.1 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB DUF4231 PF14015.6 CRJ79445.1 - 9.8 6.7 7.5 0.82 10.2 1.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) Hexokinase_1 PF00349.21 CRJ79450.1 - 1.9e-153 507.8 0.4 1.9e-75 253.2 0.1 2.2 2 0 0 2 2 2 2 Hexokinase Hexokinase_2 PF03727.16 CRJ79450.1 - 5.9e-117 389.3 0.0 5.6e-77 258.4 0.0 2.6 3 0 0 3 3 3 2 Hexokinase DUF1391 PF07151.12 CRJ79450.1 - 0.0025 17.6 0.5 4.1 7.3 0.1 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF1391) DUF5610 PF18433.1 CRJ79450.1 - 0.013 16.0 0.0 11 6.6 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5610) Herpeto_peptide PF14409.6 CRJ79450.1 - 0.026 14.8 0.0 14 6.0 0.0 2.5 2 0 0 2 2 2 0 Ribosomally synthesized peptide in Herpetosiphon YhdB PF14148.6 CRJ79450.1 - 0.067 13.3 5.1 11 6.3 0.1 3.9 5 0 0 5 5 5 0 YhdB-like protein ROK PF00480.20 CRJ79450.1 - 0.089 12.3 0.0 16 4.9 0.0 2.4 2 0 0 2 2 2 0 ROK family PqqD PF05402.12 CRJ79450.1 - 0.092 13.1 0.4 43 4.5 0.0 3.5 4 0 0 4 4 4 0 Coenzyme PQQ synthesis protein D (PqqD) Vps39_2 PF10367.9 CRJ79450.1 - 0.16 12.4 0.5 37 4.8 0.1 2.6 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 DUF3871 PF12987.7 CRJ79450.1 - 0.17 10.7 0.0 12 4.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF3871) Acetyltransf_1 PF00583.25 CRJ79454.1 - 2.8e-05 24.3 0.0 4.2e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CRJ79454.1 - 0.14 12.6 0.0 0.21 12.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CitT PF12431.8 CRJ79454.1 - 0.14 12.5 1.8 12 6.4 0.8 3.7 2 0 0 2 2 2 0 Transcriptional regulator zf_UBZ PF18439.1 CRJ79457.1 - 0.18 11.4 2.3 2 8.1 0.3 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Sgf11 PF08209.11 CRJ79457.1 - 1.5 8.5 7.4 0.16 11.5 3.1 1.6 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Pro_isomerase PF00160.21 CRJ79459.1 - 1.1e-48 165.5 0.0 1.2e-48 165.4 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf_UBZ PF18439.1 CRJ79462.1 - 0.18 11.4 2.3 2 8.1 0.3 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger ORC6 PF05460.13 CRJ79462.1 - 0.97 8.6 10.0 1.8 7.8 10.0 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Sgf11 PF08209.11 CRJ79462.1 - 1.5 8.4 7.4 0.16 11.5 3.1 1.6 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Pro_isomerase PF00160.21 CRJ79465.1 - 1.2e-48 165.3 0.0 1.4e-48 165.2 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Peptidase_A22B PF04258.13 CRJ79468.1 - 1.7e-62 211.5 8.3 2.4e-41 142.1 3.5 2.1 2 0 0 2 2 2 2 Signal peptide peptidase CobS PF02654.15 CRJ79468.1 - 0.049 13.8 0.1 0.049 13.8 0.1 2.7 3 1 0 3 3 3 0 Cobalamin-5-phosphate synthase Nop16 PF09420.10 CRJ79468.1 - 0.068 13.2 0.4 0.1 12.6 0.4 1.2 1 0 0 1 1 1 0 Ribosome biogenesis protein Nop16 Peptidase_A22B PF04258.13 CRJ79471.1 - 4.5e-31 108.4 2.8 6.3e-31 108.0 2.8 1.1 1 0 0 1 1 1 1 Signal peptide peptidase DLH PF01738.18 CRJ79476.1 - 5.1e-09 36.0 0.3 1.2e-08 34.8 0.0 1.7 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 CRJ79476.1 - 0.076 12.6 0.0 0.14 11.8 0.0 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold ACPS PF01648.20 CRJ79482.1 - 0.0002 21.5 0.0 0.00043 20.4 0.0 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily DLH PF01738.18 CRJ79486.1 - 5.8e-13 48.9 0.0 5.8e-13 48.9 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family NUDIX PF00293.28 CRJ79486.1 - 7.5e-09 35.7 1.5 7.6e-07 29.2 0.2 2.9 3 0 0 3 3 3 1 NUDIX domain TFIIA PF03153.13 CRJ79486.1 - 0.028 14.4 12.3 0.041 13.9 12.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2478 PF10649.9 CRJ79486.1 - 1 9.0 8.7 0.33 10.6 4.8 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF2478) MEIOC PF15189.6 CRJ79486.1 - 2.1 7.9 7.3 7 6.2 1.6 2.3 2 0 0 2 2 2 0 Meiosis-specific coiled-coil domain-containing protein MEIOC Carboxyl_trans PF01039.22 CRJ79496.1 - 4.8e-138 460.9 0.0 7.7e-138 460.2 0.0 1.3 1 0 0 1 1 1 1 Carboxyl transferase domain Acyl-CoA_dh_1 PF00441.24 CRJ79500.1 - 1.6e-42 145.3 1.4 2.8e-42 144.5 1.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CRJ79500.1 - 1.4e-29 103.1 0.0 2.8e-29 102.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 CRJ79500.1 - 1.5e-27 95.6 0.2 3e-27 94.7 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 CRJ79500.1 - 2.6e-15 56.9 2.0 3.8e-15 56.3 0.3 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 CRJ79500.1 - 6.7e-05 22.7 0.3 0.00018 21.3 0.3 1.7 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Carboxyl_trans PF01039.22 CRJ79505.1 - 2.1e-41 142.1 0.1 3.8e-41 141.3 0.0 1.5 2 0 0 2 2 2 1 Carboxyl transferase domain adh_short_C2 PF13561.6 CRJ79509.1 - 3e-37 128.4 0.0 3.8e-37 128.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRJ79509.1 - 2.3e-20 72.9 0.0 3.1e-20 72.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase DUF1752 PF08550.10 CRJ79513.1 - 2.2e-05 24.2 0.9 4.2e-05 23.3 0.9 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) UIM PF02809.20 CRJ79523.1 - 0.00052 19.7 3.6 0.0013 18.5 3.6 1.8 1 0 0 1 1 1 1 Ubiquitin interaction motif Clr2 PF10383.9 CRJ79531.1 - 6.4e-18 65.9 0.0 6.3e-17 62.7 0.0 2.5 2 1 0 2 2 2 1 Transcription-silencing protein Clr2 Clr2_transil PF16761.5 CRJ79531.1 - 4.2e-07 30.7 1.6 9.3e-07 29.6 1.6 1.5 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 SMC_Nse1 PF07574.13 CRJ79540.1 - 1.8e-71 240.1 0.0 3.2e-71 239.2 0.0 1.4 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 CRJ79540.1 - 3.7e-14 52.7 9.3 6e-14 52.1 9.3 1.3 1 0 0 1 1 1 1 RING-like domain zf-RING_2 PF13639.6 CRJ79540.1 - 0.1 12.9 5.9 0.21 12.0 5.9 1.5 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 CRJ79540.1 - 2.2 8.2 5.1 4.1 7.3 5.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CRJ79540.1 - 2.2 8.2 5.0 4.2 7.3 5.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) SMC_Nse1 PF07574.13 CRJ79545.1 - 1.3e-72 243.8 0.1 1.7e-72 243.4 0.1 1.1 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 CRJ79545.1 - 4.1e-15 55.8 9.7 6.5e-15 55.2 9.7 1.3 1 0 0 1 1 1 1 RING-like domain zf-C3HC4_2 PF13923.6 CRJ79545.1 - 0.084 12.7 6.5 0.18 11.7 6.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CRJ79545.1 - 0.46 10.4 6.4 1 9.3 6.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FYDLN_acid PF09538.10 CRJ79545.1 - 0.48 11.1 6.0 0.69 10.6 1.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) zf-RING_2 PF13639.6 CRJ79545.1 - 0.99 9.8 9.8 0.21 12.0 6.3 1.7 2 0 0 2 2 2 0 Ring finger domain SPRY PF00622.28 CRJ79553.1 - 0.00062 19.9 0.0 0.015 15.4 0.0 2.6 3 0 0 3 3 3 1 SPRY domain Mito_carr PF00153.27 CRJ79557.1 - 2.3e-58 194.1 0.1 1.9e-20 72.6 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EIF_2_alpha PF07541.12 CRJ79562.1 - 2.7e-37 127.4 0.0 5.1e-37 126.5 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 CRJ79562.1 - 9.4e-14 51.5 0.9 2e-13 50.5 0.9 1.6 1 0 0 1 1 1 1 S1 RNA binding domain Peptidase_S24 PF00717.23 CRJ79562.1 - 6.2e-06 26.1 0.2 6.4e-05 22.8 0.0 2.6 2 1 0 2 2 2 1 Peptidase S24-like Peptidase_S26 PF10502.9 CRJ79562.1 - 0.12 12.2 0.0 3.2 7.6 0.0 2.7 1 1 1 2 2 2 0 Signal peptidase, peptidase S26 RD3 PF14473.6 CRJ79562.1 - 0.12 12.2 0.4 0.25 11.2 0.4 1.5 1 0 0 1 1 1 0 RD3 protein Flu_M1 PF00598.19 CRJ79562.1 - 0.16 11.4 0.0 0.35 10.4 0.0 1.5 1 0 0 1 1 1 0 Influenza Matrix protein (M1) WD40 PF00400.32 CRJ79568.1 - 2.3e-14 53.5 0.1 0.0078 17.0 0.0 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRJ79568.1 - 2.5e-05 24.5 0.0 1.2 9.5 0.0 4.2 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Aldo_ket_red PF00248.21 CRJ79573.1 - 3e-66 223.6 0.0 3.4e-66 223.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family WD40 PF00400.32 CRJ79577.1 - 2e-06 28.4 0.0 0.0025 18.6 0.0 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRJ79577.1 - 0.0042 17.4 0.0 0.23 11.8 0.0 2.2 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Aldo_ket_red PF00248.21 CRJ79582.1 - 3.8e-66 223.3 0.0 4.4e-66 223.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family NADH_4Fe-4S PF10589.9 CRJ79587.1 - 0.0067 16.5 0.2 10 6.3 0.0 3.7 4 0 0 4 4 4 2 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SE PF08491.10 CRJ79595.1 - 2.3e-86 289.2 0.0 3.2e-86 288.8 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.24 CRJ79595.1 - 2e-10 40.8 0.5 3.6e-06 26.8 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 CRJ79595.1 - 1.1e-09 38.0 1.7 6.2e-05 22.4 0.2 3.0 2 1 0 2 2 2 2 FAD binding domain GIDA PF01134.22 CRJ79595.1 - 4.4e-05 22.7 0.3 0.0068 15.5 0.2 2.0 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_8 PF13450.6 CRJ79595.1 - 5.4e-05 23.3 0.4 0.00015 21.9 0.4 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CRJ79595.1 - 0.00037 19.8 0.0 0.00057 19.2 0.0 1.2 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 CRJ79595.1 - 0.0011 18.4 0.2 0.0018 17.7 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CRJ79595.1 - 0.0014 17.8 0.5 0.0034 16.5 0.2 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 CRJ79595.1 - 0.012 14.8 0.1 0.022 14.0 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 CRJ79595.1 - 0.025 14.2 0.1 0.043 13.5 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.12 CRJ79595.1 - 0.054 12.5 0.1 0.32 10.0 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_Gly3P_dh_N PF01210.23 CRJ79595.1 - 0.065 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox PF00070.27 CRJ79595.1 - 0.07 13.7 0.5 0.19 12.3 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CRJ79595.1 - 0.082 11.6 0.1 0.12 11.1 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein AA_permease_2 PF13520.6 CRJ79598.1 - 2.7e-44 151.7 42.0 4e-44 151.1 42.0 1.1 1 0 0 1 1 1 1 Amino acid permease Glycos_transf_2 PF00535.26 CRJ79598.1 - 4.3e-23 82.0 0.0 8.8e-23 81.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 AA_permease PF00324.21 CRJ79598.1 - 3.9e-20 71.9 37.1 5.5e-20 71.4 37.1 1.1 1 0 0 1 1 1 1 Amino acid permease Glyco_tranf_2_3 PF13641.6 CRJ79598.1 - 6.7e-09 36.0 0.1 2.1e-06 27.8 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 CRJ79598.1 - 0.00092 18.8 0.0 0.0016 18.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Rib_hydrolayse PF02267.17 CRJ79602.1 - 0.0012 18.3 1.7 0.0024 17.4 1.7 1.4 1 0 0 1 1 1 1 ADP-ribosyl cyclase FAM220 PF15487.6 CRJ79602.1 - 0.06 13.0 1.9 5.3 6.6 0.1 2.6 3 0 0 3 3 3 0 FAM220 family DegS PF05384.11 CRJ79602.1 - 0.76 9.3 4.7 3.7 7.0 2.6 2.3 2 0 0 2 2 2 0 Sensor protein DegS AA_permease_2 PF13520.6 CRJ79606.1 - 4e-45 154.4 39.0 5.9e-45 153.9 39.0 1.1 1 0 0 1 1 1 1 Amino acid permease Glycos_transf_2 PF00535.26 CRJ79606.1 - 5e-23 81.7 0.0 1e-22 80.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 AA_permease PF00324.21 CRJ79606.1 - 9.7e-21 73.9 35.6 1.3e-20 73.4 35.6 1.1 1 0 0 1 1 1 1 Amino acid permease Glyco_tranf_2_3 PF13641.6 CRJ79606.1 - 1.4e-08 35.0 0.2 2.3e-06 27.7 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 CRJ79606.1 - 0.00086 18.9 0.0 0.0016 18.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 BATS PF06968.13 CRJ79608.1 - 0.00032 20.8 0.0 0.00062 19.9 0.0 1.5 1 1 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain WD40 PF00400.32 CRJ79617.1 - 4.6e-14 52.6 6.4 1.1e-07 32.4 0.2 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat NACHT PF05729.12 CRJ79617.1 - 7.3e-09 35.8 0.1 2.3e-08 34.1 0.0 1.9 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 CRJ79617.1 - 3.6e-07 30.7 0.0 9e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Nup160 PF11715.8 CRJ79617.1 - 0.0045 15.7 1.6 0.091 11.4 0.3 2.2 1 1 1 2 2 2 1 Nucleoporin Nup120/160 AAA_33 PF13671.6 CRJ79617.1 - 0.0063 16.7 0.0 0.025 14.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 CRJ79617.1 - 0.015 15.8 0.1 0.031 14.7 0.1 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 CRJ79617.1 - 0.018 14.3 0.0 0.031 13.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 CRJ79617.1 - 0.024 15.0 0.1 0.067 13.6 0.0 1.8 2 0 0 2 2 2 0 RNA helicase AAA_22 PF13401.6 CRJ79617.1 - 0.027 14.8 0.0 0.092 13.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 CRJ79617.1 - 0.049 13.2 0.1 0.14 11.7 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CRJ79617.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CRJ79617.1 - 0.18 12.4 0.0 0.49 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain WD40 PF00400.32 CRJ79619.1 - 1.8e-09 38.0 3.8 0.7 10.9 0.5 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRJ79619.1 - 1.6e-05 25.1 0.0 0.033 14.5 0.0 3.3 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 CRJ79619.1 - 0.013 14.8 0.0 0.4 10.0 0.0 2.8 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Metallophos PF00149.28 CRJ79624.1 - 8.5e-35 121.1 0.1 1.2e-34 120.6 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CRJ79624.1 - 1.6e-14 54.0 0.0 3.1e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain SUR7 PF06687.12 CRJ79630.1 - 1.4e-12 47.7 0.1 1.7e-12 47.4 0.1 1.0 1 0 0 1 1 1 1 SUR7/PalI family VQ PF05678.14 CRJ79630.1 - 0.11 12.0 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 VQ motif adh_short PF00106.25 CRJ79633.1 - 1.4e-51 174.7 0.0 2e-51 174.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRJ79633.1 - 2.8e-37 128.5 0.5 3.7e-37 128.1 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRJ79633.1 - 2e-12 47.4 0.1 3.7e-12 46.5 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 CRJ79633.1 - 3.5e-06 27.0 0.4 4.6e-06 26.6 0.4 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 CRJ79633.1 - 3.8e-05 23.3 0.1 5.3e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 CRJ79633.1 - 0.00021 20.5 0.2 0.00031 20.0 0.2 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain DUF1776 PF08643.10 CRJ79633.1 - 0.01 15.2 0.0 0.014 14.8 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) F420_oxidored PF03807.17 CRJ79633.1 - 0.016 15.8 0.0 0.034 14.7 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent FHA PF00498.26 CRJ79641.1 - 1.6e-14 54.0 0.0 2.8e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CRJ79641.1 - 0.015 15.6 0.0 0.43 10.9 0.0 2.2 1 1 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain Ribo_biogen_C PF04034.13 CRJ79644.1 - 4e-49 165.6 0.0 5.5e-49 165.1 0.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 CRJ79644.1 - 6.1e-11 41.9 0.7 1.4e-10 40.8 0.7 1.6 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI BUD22 PF09073.10 CRJ79644.1 - 5.6 6.2 24.0 8.5 5.6 24.0 1.3 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 CRJ79644.1 - 7.5 5.9 24.2 12 5.2 24.2 1.3 1 0 0 1 1 1 0 SDA1 VHS PF00790.19 CRJ79649.1 - 7.6e-46 155.5 0.0 3.2e-45 153.4 0.0 2.0 2 0 0 2 2 2 1 VHS domain GAT PF03127.14 CRJ79649.1 - 8.6e-20 70.8 0.8 8.6e-20 70.8 0.8 2.1 2 0 0 2 2 2 1 GAT domain Alpha_adaptinC2 PF02883.20 CRJ79649.1 - 1.4e-18 67.2 0.4 8e-18 64.8 0.0 2.2 2 0 0 2 2 2 1 Adaptin C-terminal domain GGA_N-GAT PF18308.1 CRJ79649.1 - 1.9e-08 33.8 0.1 6.6e-08 32.0 0.1 1.9 1 0 0 1 1 1 1 GGA N-GAT domain FixG_C PF11614.8 CRJ79649.1 - 0.025 14.8 0.1 0.047 13.9 0.1 1.4 1 0 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase AP3B1_C PF14796.6 CRJ79649.1 - 0.035 14.4 0.1 0.17 12.2 0.0 2.2 2 0 0 2 2 2 0 Clathrin-adaptor complex-3 beta-1 subunit C-terminal HP_OMP_2 PF02521.14 CRJ79649.1 - 0.047 12.6 0.0 0.11 11.3 0.0 1.5 2 0 0 2 2 2 0 Putative outer membrane protein IF-2 PF11987.8 CRJ79653.1 - 8.5e-17 61.2 0.0 1.5e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU PF00009.27 CRJ79653.1 - 1.5e-11 44.2 2.2 4.4e-10 39.4 2.2 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CRJ79653.1 - 3e-07 30.5 0.0 6.1e-07 29.5 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase IF2_N PF04760.15 CRJ79653.1 - 4.6e-05 23.1 0.0 9.1e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region GTP_EFTU_D4 PF14578.6 CRJ79653.1 - 0.013 15.4 0.2 0.026 14.4 0.2 1.4 1 0 0 1 1 1 0 Elongation factor Tu domain 4 SRPRB PF09439.10 CRJ79653.1 - 0.017 14.6 0.0 0.03 13.8 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit GTP_EFTU_D2 PF03144.25 CRJ79653.1 - 0.11 12.9 0.6 0.22 11.9 0.6 1.4 1 0 0 1 1 1 0 Elongation factor Tu domain 2 PP28 PF10252.9 CRJ79662.1 - 4e-25 88.1 11.0 4e-25 88.1 11.0 3.4 2 1 1 3 3 3 1 Casein kinase substrate phosphoprotein PP28 CENP-B_dimeris PF09026.10 CRJ79662.1 - 0.28 11.6 22.7 0.083 13.3 7.9 2.7 3 0 0 3 3 3 0 Centromere protein B dimerisation domain HGWP PF03578.15 CRJ79671.1 - 8.2 6.0 8.8 0.21 11.1 1.7 2.0 2 0 0 2 2 2 0 HGWP repeat CoA_trans PF01144.23 CRJ79676.1 - 2.6e-71 239.5 0.5 1.3e-34 119.5 0.0 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 CRJ79676.1 - 0.00068 19.6 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain CoA_trans PF01144.23 CRJ79679.1 - 0.16 11.3 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Coenzyme A transferase Nrap_D5 PF17406.2 CRJ79684.1 - 1.1e-57 194.3 0.6 5e-57 192.2 0.8 2.0 2 0 0 2 2 2 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D4 PF17405.2 CRJ79684.1 - 6.6e-57 192.3 0.1 1.1e-56 191.5 0.1 1.3 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D2 PF17403.2 CRJ79684.1 - 8.8e-50 168.4 0.1 1.2e-46 158.2 0.0 2.4 2 0 0 2 2 2 2 Nrap protein PAP/OAS-like domain Nrap_D3 PF17404.2 CRJ79684.1 - 7.9e-45 152.8 0.1 2.2e-44 151.4 0.0 1.7 2 0 0 2 2 2 1 Nrap protein domain 3 Nrap PF03813.14 CRJ79684.1 - 8.7e-38 129.8 0.0 1.6e-37 128.9 0.0 1.4 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D6 PF17407.2 CRJ79684.1 - 4.5e-34 117.6 0.0 1.2e-33 116.1 0.0 1.8 1 0 0 1 1 1 1 Nrap protein domain 6 DNA_pol_phi PF04931.13 CRJ79684.1 - 0.00043 18.5 5.9 0.00064 18.0 5.9 1.1 1 0 0 1 1 1 1 DNA polymerase phi FAM176 PF14851.6 CRJ79684.1 - 0.12 12.0 1.8 0.23 11.1 1.8 1.4 1 0 0 1 1 1 0 FAM176 family GLE1 PF07817.13 CRJ79684.1 - 0.19 10.9 0.0 0.3 10.3 0.0 1.3 1 0 0 1 1 1 0 GLE1-like protein Nop14 PF04147.12 CRJ79684.1 - 0.53 8.4 6.3 0.81 7.8 6.3 1.1 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.13 CRJ79684.1 - 0.92 9.4 5.5 2.3 8.0 5.5 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region RXT2_N PF08595.11 CRJ79684.1 - 0.95 9.5 4.8 2.4 8.2 4.8 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF2457 PF10446.9 CRJ79684.1 - 2.7 7.0 11.5 4.6 6.3 11.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.12 CRJ79684.1 - 3.5 6.9 9.8 5.5 6.2 9.8 1.2 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.12 CRJ79684.1 - 4.5 6.9 12.3 7.8 6.2 12.3 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CENP-B_dimeris PF09026.10 CRJ79684.1 - 6.2 7.3 13.6 15 6.0 13.6 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain I-set PF07679.16 CRJ79688.1 - 0.02 14.9 0.5 2.8 8.1 0.1 4.5 7 0 0 7 7 7 0 Immunoglobulin I-set domain DUF1918 PF08940.11 CRJ79688.1 - 0.036 13.7 2.6 0.3 10.8 0.1 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF1918) Peptidase_C12 PF01088.21 CRJ79693.1 - 7.8e-61 205.5 0.3 2.1e-60 204.1 0.3 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Transglut_core2 PF13369.6 CRJ79698.1 - 1.4e-17 63.7 0.0 1.9e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 Transglutaminase-like superfamily YccV-like PF08755.11 CRJ79698.1 - 2.9e-06 27.7 0.1 0.00021 21.7 0.1 2.4 1 1 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like PACT_coil_coil PF10495.9 CRJ79702.1 - 3.4e-23 82.0 1.0 3.4e-23 82.0 1.0 3.3 3 1 1 4 4 4 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein TPR_MLP1_2 PF07926.12 CRJ79702.1 - 0.00068 19.7 9.5 0.00068 19.7 9.5 4.8 2 1 2 5 5 5 3 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 CRJ79702.1 - 0.002 17.1 12.8 0.002 17.1 12.8 2.6 1 1 1 2 2 2 1 Spc7 kinetochore protein UPF0242 PF06785.11 CRJ79702.1 - 0.17 11.9 25.5 1.6 8.8 12.3 2.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus GAS PF13851.6 CRJ79702.1 - 0.19 11.1 33.9 0.22 10.8 11.1 2.9 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding DUF3450 PF11932.8 CRJ79702.1 - 0.58 9.4 26.8 0.59 9.4 10.1 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Atg14 PF10186.9 CRJ79702.1 - 0.6 9.1 28.7 0.81 8.7 5.6 2.4 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 BRE1 PF08647.11 CRJ79702.1 - 0.6 10.2 29.0 0.46 10.6 9.5 3.7 2 1 2 4 4 4 0 BRE1 E3 ubiquitin ligase DUF5344 PF17279.2 CRJ79702.1 - 4.5 7.9 12.8 8 7.1 1.3 2.8 1 1 0 2 2 2 0 Family of unknown function (DUF5344) Peptidase_C14 PF00656.22 CRJ79705.1 - 1.8e-64 218.1 0.1 2.3e-64 217.7 0.1 1.1 1 0 0 1 1 1 1 Caspase domain TLD PF07534.16 CRJ79723.1 - 3.5e-18 66.2 0.0 2.8e-11 43.8 0.0 2.1 2 0 0 2 2 2 2 TLD DUF3729 PF12526.8 CRJ79723.1 - 1.2 10.8 10.7 0.35 12.4 3.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3729) Peptidase_C14 PF00656.22 CRJ79733.1 - 5.9e-64 216.4 0.1 1.8e-63 214.8 0.1 1.8 2 0 0 2 2 2 1 Caspase domain Pkinase PF00069.25 CRJ79733.1 - 3.2e-28 98.8 0.0 3.2e-16 59.5 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CRJ79733.1 - 2.7e-08 33.4 0.0 4.6e-05 22.8 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase S_100 PF01023.19 CRJ79733.1 - 0.034 13.8 1.2 0.061 13.0 0.1 1.9 2 0 0 2 2 2 0 S-100/ICaBP type calcium binding domain TLD PF07534.16 CRJ79739.1 - 4.2e-22 78.9 0.0 2.9e-11 43.7 0.0 2.1 2 0 0 2 2 2 2 TLD Sec23_trunk PF04811.15 CRJ79744.1 - 1e-34 120.2 0.0 1.6e-34 119.6 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 CRJ79744.1 - 1.6e-24 85.7 0.0 4e-24 84.4 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 CRJ79744.1 - 9.6e-17 60.8 4.1 1.7e-16 59.9 4.1 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 CRJ79744.1 - 6.3e-10 38.8 0.0 1.4e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Sec23_BS PF08033.12 CRJ79744.1 - 3.5e-07 30.9 0.0 8.8e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Vps36-NZF-N PF16988.5 CRJ79744.1 - 0.0094 15.3 0.1 0.023 14.1 0.1 1.6 1 0 0 1 1 1 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain Sec23_trunk PF04811.15 CRJ79750.1 - 2.2e-71 240.3 0.0 3.2e-71 239.7 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 CRJ79750.1 - 1.1e-24 86.2 0.1 5.5e-24 83.9 0.0 2.2 2 1 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 CRJ79750.1 - 6.8e-17 62.0 0.0 1.6e-16 60.8 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 CRJ79750.1 - 1.3e-16 60.3 4.1 2.3e-16 59.6 4.1 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 CRJ79750.1 - 5.7e-10 38.9 0.0 1.3e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 CRJ79750.1 - 0.013 14.8 0.1 0.03 13.7 0.1 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Fungal_trans_2 PF11951.8 CRJ79758.1 - 8.3e-11 41.3 0.4 1.6e-10 40.4 0.4 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRJ79758.1 - 2.7e-06 27.4 12.4 4.8e-06 26.6 12.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 CRJ79763.1 - 6.4e-07 29.4 12.4 6.4e-07 29.4 12.4 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IBN_N PF03810.19 CRJ79773.1 - 5.8e-05 22.9 1.0 0.00082 19.2 0.0 3.3 4 0 0 4 4 4 1 Importin-beta N-terminal domain Xpo1 PF08389.12 CRJ79773.1 - 0.00061 19.9 0.1 0.0046 17.0 0.0 2.6 2 0 0 2 2 2 1 Exportin 1-like protein DUF1917 PF08939.10 CRJ79780.1 - 4e-92 308.8 0.1 5.7e-92 308.3 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) ANAPC4_WD40 PF12894.7 CRJ79784.1 - 0.0062 16.8 0.0 0.021 15.1 0.0 1.8 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain DUF1917 PF08939.10 CRJ79789.1 - 3.7e-90 302.4 0.0 5.3e-90 301.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) Acetyltransf_1 PF00583.25 CRJ79793.1 - 1.2e-19 70.7 0.0 1.5e-19 70.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CRJ79793.1 - 2.3e-11 43.7 0.0 3.4e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CRJ79793.1 - 1.2e-10 41.6 0.0 1.7e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CRJ79793.1 - 3.4e-10 39.8 0.0 5.4e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 CRJ79793.1 - 2.8e-07 31.3 0.0 3.5e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CRJ79793.1 - 3e-06 27.3 0.0 4.9e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 CRJ79793.1 - 7.7e-06 25.7 0.0 9.3e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CRJ79793.1 - 0.0028 17.8 0.0 0.0049 17.0 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.6 CRJ79793.1 - 0.033 14.2 0.0 0.068 13.2 0.0 1.5 1 1 0 1 1 1 0 ESCO1/2 acetyl-transferase LCAT PF02450.15 CRJ79798.1 - 2.3e-107 359.6 0.0 2.8e-107 359.3 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 CRJ79798.1 - 0.0011 19.6 0.6 0.004 17.8 0.1 2.0 1 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CRJ79798.1 - 0.034 13.4 0.0 0.077 12.2 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PH PF00169.29 CRJ79808.1 - 0.0015 19.0 0.0 0.0039 17.7 0.0 1.7 1 0 0 1 1 1 1 PH domain DUF5344 PF17279.2 CRJ79808.1 - 0.018 15.6 0.3 0.96 10.1 0.2 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5344) Prominin PF05478.11 CRJ79808.1 - 0.062 11.2 0.3 0.095 10.7 0.3 1.1 1 0 0 1 1 1 0 Prominin tRNA-synt_2b PF00587.25 CRJ79815.1 - 1.7e-31 109.5 0.0 1.7e-29 103.1 0.0 2.4 3 0 0 3 3 3 2 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 CRJ79815.1 - 7.8e-21 74.0 0.2 1.3e-20 73.3 0.2 1.4 1 0 0 1 1 1 1 Anticodon binding domain CDP-OH_P_transf PF01066.21 CRJ79821.1 - 2.2e-13 50.7 0.9 5.8e-13 49.4 0.9 1.7 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Metallopep PF12044.8 CRJ79825.1 - 3.4e-130 434.5 0.0 4.4e-130 434.1 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.17 CRJ79825.1 - 0.0011 18.8 0.1 0.037 13.9 0.1 2.5 1 1 0 1 1 1 1 Jacalin-like lectin domain Whi5 PF08528.11 CRJ79828.1 - 4e-09 35.9 0.1 8.1e-09 34.9 0.1 1.5 1 0 0 1 1 1 1 Whi5 like HEM4 PF02602.15 CRJ79831.1 - 2.2e-38 131.9 0.0 3e-38 131.5 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Evr1_Alr PF04777.13 CRJ79833.1 - 8.4e-30 103.2 0.6 8.4e-30 103.2 0.6 1.6 2 0 0 2 2 2 1 Erv1 / Alr family CotE PF10628.9 CRJ79833.1 - 0.059 13.0 0.0 0.085 12.5 0.0 1.2 1 0 0 1 1 1 0 Outer spore coat protein E (CotE) THUMP PF02926.17 CRJ79836.1 - 1.8e-11 44.4 0.1 8.5e-11 42.1 0.0 2.1 1 1 1 2 2 2 1 THUMP domain HYLS1_C PF15311.6 CRJ79836.1 - 0.17 12.7 0.0 0.96 10.3 0.0 2.1 2 0 0 2 2 2 0 Hydrolethalus syndrome protein 1 C-terminus ChaB PF06150.12 CRJ79840.1 - 0.096 13.3 0.5 0.56 10.8 0.0 2.2 2 0 0 2 2 2 0 ChaB PPP4R2 PF09184.11 CRJ79840.1 - 0.098 12.2 2.8 0.16 11.6 2.8 1.3 1 0 0 1 1 1 0 PPP4R2 SGT1 PF07093.11 CRJ79845.1 - 2.3e-86 290.5 16.0 4.3e-80 269.8 0.0 3.2 3 0 0 3 3 3 3 SGT1 protein SMC_N PF02463.19 CRJ79848.1 - 3e-20 72.6 17.6 2.5e-19 69.6 17.7 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 CRJ79848.1 - 6.6e-12 45.8 3.0 6.6e-12 45.8 3.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 CRJ79848.1 - 1.9e-07 31.8 32.8 1.9e-07 31.8 32.8 5.7 2 2 0 2 2 1 1 AAA domain AAA_21 PF13304.6 CRJ79848.1 - 2.3e-07 30.9 2.5 3.9e-05 23.6 0.1 3.0 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CRJ79848.1 - 0.0035 17.0 0.0 0.0091 15.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain HrpB7 PF09486.10 CRJ79848.1 - 0.0038 17.6 18.4 0.0038 17.6 18.4 7.1 3 2 2 5 5 5 1 Bacterial type III secretion protein (HrpB7) SbcCD_C PF13558.6 CRJ79848.1 - 0.018 15.2 0.0 0.1 12.9 0.0 2.3 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Ploopntkinase3 PF18751.1 CRJ79848.1 - 0.03 14.2 1.4 0.63 9.9 0.0 2.7 2 1 0 2 2 2 0 P-loop Nucleotide Kinase3 SMC_hinge PF06470.13 CRJ79848.1 - 0.065 13.5 0.0 0.27 11.6 0.0 2.2 1 1 0 1 1 1 0 SMC proteins Flexible Hinge Domain Pox_A_type_inc PF04508.12 CRJ79848.1 - 0.081 12.8 0.4 0.54 10.2 0.4 2.6 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Spc7 PF08317.11 CRJ79848.1 - 0.37 9.6 83.1 0.11 11.4 7.0 5.3 3 2 2 5 5 5 0 Spc7 kinetochore protein AAA_22 PF13401.6 CRJ79848.1 - 0.94 9.8 0.0 0.94 9.8 0.0 3.2 4 0 0 4 4 3 0 AAA domain COQ9 PF08511.11 CRJ79854.1 - 1.1e-30 105.2 0.0 2e-30 104.4 0.0 1.5 1 0 0 1 1 1 1 COQ9 ChaB PF06150.12 CRJ79858.1 - 0.023 15.3 0.2 0.33 11.6 0.0 2.4 2 0 0 2 2 2 0 ChaB PPP4R2 PF09184.11 CRJ79858.1 - 0.034 13.8 3.2 0.049 13.2 3.2 1.2 1 0 0 1 1 1 0 PPP4R2 DUF913 PF06025.12 CRJ79858.1 - 0.14 11.1 0.1 0.23 10.4 0.1 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) TRAP_alpha PF03896.16 CRJ79858.1 - 0.18 10.9 1.9 0.27 10.4 1.9 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Sigma70_ner PF04546.13 CRJ79858.1 - 0.31 10.9 5.0 0.23 11.3 2.8 1.8 2 0 0 2 2 2 0 Sigma-70, non-essential region RRN3 PF05327.11 CRJ79858.1 - 1.7 7.1 3.4 2.4 6.6 3.4 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.14 CRJ79858.1 - 2.4 6.3 5.5 3.3 5.9 5.5 1.2 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 CRJ79858.1 - 9 4.3 12.2 15 3.5 12.0 1.3 2 0 0 2 2 2 0 DNA polymerase phi SGT1 PF07093.11 CRJ79862.1 - 2e-84 284.1 1.6 3.6e-83 280.0 0.0 2.1 2 0 0 2 2 2 2 SGT1 protein DUF5456 PF17539.2 CRJ79862.1 - 0.2 11.5 0.0 0.36 10.7 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5456) SMC_N PF02463.19 CRJ79867.1 - 5.7e-21 75.0 15.3 4.8e-20 71.9 15.3 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 CRJ79867.1 - 4e-12 46.5 0.1 4e-12 46.5 0.1 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 CRJ79867.1 - 4.3e-08 33.9 29.7 4.3e-08 33.9 29.7 5.7 2 2 0 2 2 1 1 AAA domain AAA_21 PF13304.6 CRJ79867.1 - 2e-07 31.1 2.3 3.9e-05 23.6 0.1 3.0 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system HrpB7 PF09486.10 CRJ79867.1 - 0.0008 19.8 19.4 0.0008 19.8 19.4 6.8 4 2 1 5 5 5 1 Bacterial type III secretion protein (HrpB7) AAA_29 PF13555.6 CRJ79867.1 - 0.0034 17.1 0.0 0.0091 15.7 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 CRJ79867.1 - 0.021 15.0 0.0 0.1 12.9 0.0 2.2 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Ploopntkinase3 PF18751.1 CRJ79867.1 - 0.025 14.5 1.2 0.63 9.9 0.0 2.9 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Pox_A_type_inc PF04508.12 CRJ79867.1 - 0.096 12.6 0.4 0.54 10.2 0.4 2.4 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat AAA_22 PF13401.6 CRJ79867.1 - 0.94 9.8 0.0 0.94 9.8 0.0 3.2 4 0 0 4 4 3 0 AAA domain Spc7 PF08317.11 CRJ79867.1 - 3.5 6.4 83.9 0.15 10.9 7.7 5.3 2 2 2 5 5 5 0 Spc7 kinetochore protein COQ9 PF08511.11 CRJ79872.1 - 1e-30 105.3 0.1 2e-30 104.4 0.0 1.5 2 0 0 2 2 2 1 COQ9 Pyr_redox_2 PF07992.14 CRJ79877.1 - 3.2e-136 453.3 20.0 3.1e-68 230.2 6.2 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CRJ79877.1 - 2.8e-68 227.1 0.0 1.2e-38 131.7 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain RRM_1 PF00076.22 CRJ79877.1 - 9.3e-57 188.8 0.0 1.4e-15 56.8 0.0 6.4 5 1 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FA_desaturase PF00487.24 CRJ79877.1 - 2.6e-44 152.0 63.5 4.8e-22 79.0 27.7 2.4 2 0 0 2 2 2 2 Fatty acid desaturase MIF4G PF02854.19 CRJ79877.1 - 6.7e-44 150.1 0.1 7.5e-21 74.7 0.0 2.8 2 0 0 2 2 2 2 MIF4G domain Pyr_redox PF00070.27 CRJ79877.1 - 6.7e-44 148.3 22.3 1.2e-19 70.7 0.7 5.1 4 0 0 4 4 4 4 Pyridine nucleotide-disulphide oxidoreductase MA3 PF02847.17 CRJ79877.1 - 2.9e-23 82.0 0.0 5.1e-10 39.3 0.0 3.0 2 0 0 2 2 2 2 MA3 domain NAD_binding_8 PF13450.6 CRJ79877.1 - 3.2e-18 65.7 11.9 2.1e-05 24.7 0.2 4.8 4 0 0 4 4 4 4 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 CRJ79877.1 - 1.1e-15 57.9 15.7 9.7e-08 31.8 0.3 4.6 4 0 0 4 4 4 2 FAD dependent oxidoreductase GIDA PF01134.22 CRJ79877.1 - 6.2e-14 51.9 20.2 3.2e-07 29.8 0.7 4.1 3 1 0 4 4 4 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 CRJ79877.1 - 7.1e-12 45.1 19.5 7.3e-06 25.3 2.3 4.8 6 0 0 6 6 6 2 FAD binding domain Pyr_redox_3 PF13738.6 CRJ79877.1 - 9.7e-11 41.5 6.3 0.017 14.4 0.0 4.2 4 0 0 4 4 4 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CRJ79877.1 - 4.7e-08 32.5 0.3 0.68 9.0 0.0 4.5 4 0 0 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 CRJ79877.1 - 1.3e-07 31.2 14.6 0.082 12.2 0.4 4.4 4 0 0 4 4 4 4 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 CRJ79877.1 - 3.2e-07 29.8 9.8 0.0085 15.4 0.1 4.2 4 0 0 4 4 4 2 Thi4 family FAD_binding_3 PF01494.19 CRJ79877.1 - 1.6e-06 27.6 18.6 0.091 12.0 0.2 4.4 4 0 0 4 4 4 4 FAD binding domain HI0933_like PF03486.14 CRJ79877.1 - 1.5e-05 23.9 31.6 0.00087 18.1 2.0 6.7 8 0 0 8 8 8 2 HI0933-like protein ATP-grasp_2 PF08442.10 CRJ79877.1 - 0.00025 20.7 0.0 1.8 8.1 0.0 3.4 3 0 0 3 3 3 2 ATP-grasp domain Lycopene_cycl PF05834.12 CRJ79877.1 - 0.0013 17.9 6.7 0.45 9.5 0.0 3.8 4 0 0 4 4 4 2 Lycopene cyclase protein RRM_5 PF13893.6 CRJ79877.1 - 0.0025 17.4 0.0 0.28 10.8 0.0 3.5 3 1 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NAD_kinase PF01513.21 CRJ79877.1 - 0.012 14.8 0.1 5 6.2 0.0 2.3 2 0 0 2 2 2 0 ATP-NAD kinase FANCI_S1 PF14675.6 CRJ79877.1 - 0.012 15.1 1.8 3 7.3 0.1 2.3 2 0 0 2 2 2 0 FANCI solenoid 1 UPF0051 PF01458.17 CRJ79877.1 - 0.054 13.2 0.0 14 5.3 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized protein family (UPF0051) Tho1_MOS11_C PF18592.1 CRJ79877.1 - 0.062 13.1 2.7 9.2 6.2 0.3 2.8 2 0 0 2 2 2 0 Tho1/MOS11 C-terminal domain PI3K_P85_iSH2 PF16454.5 CRJ79877.1 - 0.12 12.0 0.1 23 4.6 0.0 2.4 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain YoaP PF14268.6 CRJ79877.1 - 0.13 11.8 0.3 23 4.6 0.0 2.5 2 0 0 2 2 2 0 YoaP-like Trp_halogenase PF04820.14 CRJ79877.1 - 0.4 9.5 8.0 3.6 6.3 1.0 2.6 2 0 0 2 2 2 0 Tryptophan halogenase FMO-like PF00743.19 CRJ79877.1 - 1.2 7.4 6.1 6.6 5.0 0.6 2.2 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like SRP14 PF02290.15 CRJ79887.1 - 4.2e-28 97.6 0.0 6.7e-28 96.9 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle 14kD protein SRP14 PF02290.15 CRJ79904.1 - 5.3e-28 97.2 0.0 8.4e-28 96.6 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle 14kD protein Vac14_Fig4_bd PF11916.8 CRJ79914.1 - 2.1e-81 271.9 8.3 5e-81 270.6 8.3 1.7 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 CRJ79914.1 - 3.9e-44 149.2 0.2 4.1e-41 139.5 0.0 3.7 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region DnaJ PF00226.31 CRJ79914.1 - 5e-21 74.6 1.7 1.4e-20 73.2 1.7 1.9 1 0 0 1 1 1 1 DnaJ domain TPR_1 PF00515.28 CRJ79914.1 - 5e-10 38.8 2.0 0.0003 20.5 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 CRJ79914.1 - 1.4e-08 34.8 2.5 0.00095 19.3 0.1 4.5 3 0 0 3 3 3 2 Tetratricopeptide repeat HEAT PF02985.22 CRJ79914.1 - 1.5e-07 31.1 0.4 0.001 19.2 0.0 4.6 3 0 0 3 3 3 1 HEAT repeat TPR_14 PF13428.6 CRJ79914.1 - 3.9e-07 30.3 8.1 0.02 15.6 0.0 5.9 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 CRJ79914.1 - 4.6e-07 29.4 0.3 0.0023 17.6 0.0 3.9 2 1 1 3 3 3 2 TPR repeat Cnd1 PF12717.7 CRJ79914.1 - 1.2e-06 28.6 1.8 0.014 15.5 0.3 3.8 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 TPR_8 PF13181.6 CRJ79914.1 - 2.3e-06 27.4 0.1 0.021 15.0 0.0 5.5 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 CRJ79914.1 - 1.1e-05 25.2 16.8 0.069 13.3 0.0 6.7 7 0 0 7 7 5 2 Tetratricopeptide repeat HEAT_EZ PF13513.6 CRJ79914.1 - 8.1e-05 23.0 7.3 0.0031 18.0 0.1 4.0 5 0 0 5 5 2 2 HEAT-like repeat TPR_17 PF13431.6 CRJ79914.1 - 0.00045 20.4 4.6 0.007 16.7 0.0 4.3 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 CRJ79914.1 - 0.0011 19.5 8.6 0.082 13.4 0.0 5.0 3 1 1 4 4 3 1 Tetratricopeptide repeat HEAT_2 PF13646.6 CRJ79914.1 - 0.0038 17.6 0.7 3.8 8.0 0.0 4.2 3 1 0 3 3 3 1 HEAT repeats TPR_7 PF13176.6 CRJ79914.1 - 0.0043 17.0 13.3 1 9.5 0.1 6.1 5 1 1 6 6 6 1 Tetratricopeptide repeat Arm PF00514.23 CRJ79914.1 - 0.0051 16.8 0.0 0.77 9.9 0.0 4.1 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat ArnB_C PF18677.1 CRJ79914.1 - 0.1 12.7 1.7 0.25 11.5 0.2 2.4 2 0 0 2 2 2 0 Archaellum regulatory network B, C-terminal domain TPR_16 PF13432.6 CRJ79914.1 - 0.12 13.1 0.1 0.12 13.1 0.1 4.9 3 1 3 6 6 5 0 Tetratricopeptide repeat DUF4398 PF14346.6 CRJ79914.1 - 2.5 8.8 14.6 7 7.4 0.7 3.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) TPR_6 PF13174.6 CRJ79914.1 - 6.2 7.7 14.8 8.8 7.2 0.0 6.7 8 0 0 8 8 5 0 Tetratricopeptide repeat APG9 PF04109.16 CRJ79923.1 - 1.7e-192 640.7 11.4 2.1e-192 640.4 11.4 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 Mito_carr PF00153.27 CRJ79923.1 - 1.7e-64 213.7 6.2 7.8e-22 77.0 0.4 3.5 2 1 1 3 3 3 3 Mitochondrial carrier protein COG6 PF06419.11 CRJ79929.1 - 2.1e-211 703.4 6.2 2.4e-211 703.3 6.2 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 COG2 PF06148.11 CRJ79929.1 - 0.037 14.1 0.8 0.38 10.8 0.0 2.9 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Forkhead PF00250.18 CRJ79929.1 - 0.058 13.6 0.1 0.13 12.5 0.1 1.5 1 0 0 1 1 1 0 Forkhead domain CofC PF01983.16 CRJ79929.1 - 0.14 11.3 0.0 0.41 9.8 0.0 1.7 1 0 0 1 1 1 0 Guanylyl transferase CofC like Ribosomal_S17 PF00366.20 CRJ79932.1 - 2.1e-23 82.2 1.8 2.1e-23 82.2 1.8 1.7 2 0 0 2 2 2 1 Ribosomal protein S17 RelB PF04221.12 CRJ79932.1 - 0.062 13.3 0.1 0.13 12.2 0.0 1.7 2 0 0 2 2 2 0 RelB antitoxin EMG1 PF03587.14 CRJ79934.1 - 3.2e-78 261.8 0.0 3.8e-78 261.6 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Cys_Met_Meta_PP PF01053.20 CRJ79938.1 - 3e-32 111.6 0.0 4.4e-32 111.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 CRJ79938.1 - 0.098 11.8 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II SPX PF03105.19 CRJ79940.1 - 1e-56 193.5 1.3 1.4e-40 140.4 0.0 2.1 2 0 0 2 2 2 2 SPX domain zf-C3HC4 PF00097.25 CRJ79940.1 - 3.2e-07 30.1 10.4 5.1e-07 29.4 10.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CRJ79940.1 - 4.4e-07 29.7 9.7 6.8e-07 29.1 9.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CRJ79940.1 - 5e-07 29.8 8.8 8.7e-07 29.0 8.8 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 CRJ79940.1 - 5.8e-07 29.2 9.6 1e-06 28.4 9.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CRJ79940.1 - 2.8e-05 24.4 11.2 4.9e-05 23.6 11.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 CRJ79940.1 - 5.5e-05 23.0 9.6 0.0001 22.2 9.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CRJ79940.1 - 0.00022 21.2 7.8 0.00044 20.2 7.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 CRJ79940.1 - 0.0062 16.4 8.8 0.022 14.6 9.0 1.8 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 TerY_C PF15616.6 CRJ79940.1 - 0.045 13.9 0.9 0.076 13.1 0.9 1.3 1 0 0 1 1 1 0 TerY-C metal binding domain zf-RING_6 PF14835.6 CRJ79940.1 - 0.048 13.5 2.7 0.1 12.5 2.7 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 CRJ79940.1 - 0.062 13.6 9.0 0.14 12.5 9.0 1.6 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CRJ79940.1 - 0.062 13.4 1.5 0.12 12.5 1.5 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 CRJ79940.1 - 0.11 12.6 4.1 0.21 11.7 4.1 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 CRJ79940.1 - 0.22 11.3 9.0 0.088 12.6 6.0 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DnaJ PF00226.31 CRJ79943.1 - 1.6e-24 85.8 0.9 5.3e-24 84.1 0.9 2.0 1 0 0 1 1 1 1 DnaJ domain R3H PF01424.22 CRJ79943.1 - 4.2e-15 55.5 0.1 1.5e-14 53.7 0.0 2.0 2 0 0 2 2 2 1 R3H domain zf-C2H2_jaz PF12171.8 CRJ79943.1 - 6.8e-10 39.0 3.7 1.4e-09 38.0 3.7 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding G-patch PF01585.23 CRJ79943.1 - 1.5e-09 37.6 3.7 4.2e-09 36.1 3.7 1.8 1 0 0 1 1 1 1 G-patch domain zf-met PF12874.7 CRJ79943.1 - 8.4e-09 35.5 1.2 1.8e-08 34.5 1.2 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 CRJ79943.1 - 0.00051 20.3 0.5 0.0013 19.1 0.5 1.6 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) G-patch_2 PF12656.7 CRJ79943.1 - 0.0006 19.9 2.8 0.0023 18.0 2.8 2.1 1 0 0 1 1 1 1 G-patch domain zf-C2H2 PF00096.26 CRJ79943.1 - 0.019 15.4 0.5 0.045 14.2 0.5 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type RPT PF13446.6 CRJ79943.1 - 0.045 13.7 0.1 0.15 12.0 0.1 2.0 1 0 0 1 1 1 0 A repeated domain in UCH-protein zf-C2H2_4 PF13894.6 CRJ79943.1 - 0.1 13.5 0.2 0.26 12.2 0.2 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CRJ79943.1 - 0.13 12.3 1.6 0.27 11.3 1.6 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger Peptidase_C54 PF03416.19 CRJ79947.1 - 8.9e-88 294.3 0.0 1.2e-87 293.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 Histone PF00125.24 CRJ79952.1 - 4.5e-22 78.8 2.0 5.6e-22 78.5 2.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CRJ79952.1 - 3.9e-05 23.8 0.0 9.6e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 CRJ79952.1 - 0.00033 21.1 0.0 0.00058 20.3 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.13 CRJ79952.1 - 0.026 14.2 0.1 0.064 12.9 0.1 1.6 1 1 0 1 1 1 0 Replication protein C N-terminal domain DUF3915 PF13054.6 CRJ79952.1 - 0.16 12.0 0.0 0.2 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Histone PF00125.24 CRJ79956.1 - 4.9e-19 69.0 1.4 5.8e-19 68.7 1.4 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CRJ79956.1 - 0.00037 20.7 0.0 0.00086 19.5 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 CRJ79956.1 - 0.0053 17.2 0.0 0.0071 16.8 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Histone_H2A_C PF16211.5 CRJ79961.1 - 4.3e-21 74.3 2.9 7.6e-21 73.6 2.9 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 CRJ79961.1 - 6.8e-17 62.1 0.0 9.3e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CRJ79961.1 - 1e-05 25.7 0.0 1.4e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Complex1_LYR PF05347.15 CRJ79966.1 - 1e-09 38.3 2.9 1.3e-09 37.9 2.9 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) MFS_1 PF07690.16 CRJ79971.1 - 1.4e-47 162.4 38.1 1.4e-47 162.4 38.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CRJ79971.1 - 1.8e-11 43.6 27.7 7.1e-11 41.6 27.7 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 CRJ79971.1 - 0.00029 19.4 3.7 0.00029 19.4 3.7 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Trypan_PARP PF05887.11 CRJ79971.1 - 1.5 8.8 9.7 2.9 7.9 9.7 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) CorA PF01544.18 CRJ79976.1 - 7.6e-05 22.2 0.1 0.00011 21.6 0.1 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Peptidase_M56 PF05569.11 CRJ79981.1 - 0.26 10.4 8.0 0.5 9.5 8.0 1.4 1 0 0 1 1 1 0 BlaR1 peptidase M56 Rootletin PF15035.6 CRJ79987.1 - 0.0018 18.4 0.2 0.0026 17.8 0.2 1.3 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion HET PF06985.11 CRJ79991.1 - 4.6e-32 111.4 2.9 7.1e-32 110.8 2.9 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NUDIX PF00293.28 CRJ79991.1 - 4.8e-07 29.9 0.1 1.2e-06 28.6 0.1 1.6 1 0 0 1 1 1 1 NUDIX domain FAD_binding_4 PF01565.23 CRJ79997.1 - 4.2e-22 78.4 1.9 8.1e-22 77.5 1.9 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 CRJ79997.1 - 2.4e-07 30.8 0.2 4.4e-07 29.9 0.2 1.5 1 0 0 1 1 1 1 Berberine and berberine like p450 PF00067.22 CRJ80005.1 - 0.0044 15.8 0.0 0.0049 15.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 CAP PF00188.26 CRJ80010.1 - 3.2e-20 73.2 0.9 4.7e-20 72.7 0.9 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family PEP_mutase PF13714.6 CRJ80013.1 - 1.2e-64 218.1 0.2 1.6e-64 217.7 0.2 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Abhydrolase_1 PF00561.20 CRJ80013.1 - 2.7e-11 43.6 0.0 4.2e-08 33.2 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CRJ80013.1 - 1e-08 36.1 0.2 1.8e-08 35.3 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CRJ80013.1 - 1.8e-05 24.1 0.0 6.2e-05 22.4 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 CRJ80013.1 - 0.00076 18.3 0.0 0.0045 15.7 0.0 1.9 1 1 1 2 2 2 1 Ndr family CorA PF01544.18 CRJ80025.1 - 0.0022 17.4 13.0 0.012 14.9 13.0 2.1 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein EMP70 PF02990.16 CRJ80025.1 - 0.49 9.0 2.6 0.55 8.8 1.5 1.5 2 0 0 2 2 2 0 Endomembrane protein 70 DHR10 PF18595.1 CRJ80025.1 - 4.5 7.4 8.5 10 6.2 3.6 2.6 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain CCDC-167 PF15188.6 CRJ80025.1 - 5 7.5 6.6 1.3 9.4 2.3 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Pkinase PF00069.25 CRJ80031.1 - 8.5e-19 67.9 0.0 3.7e-18 65.8 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRJ80031.1 - 3.3e-09 36.4 0.0 5.7e-08 32.4 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase D-ser_dehydrat PF14031.6 CRJ80034.1 - 9.3e-22 77.5 0.0 2.3e-21 76.3 0.0 1.7 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 CRJ80034.1 - 4.8e-13 49.3 0.2 7.6e-13 48.6 0.2 1.3 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain TIM PF00121.18 CRJ80037.1 - 1.3e-41 142.6 0.0 2.2e-41 141.9 0.0 1.3 1 0 0 1 1 1 1 Triosephosphate isomerase Ferritin PF00210.24 CRJ80037.1 - 2e-05 24.5 0.0 0.04 13.8 0.0 2.3 2 0 0 2 2 2 2 Ferritin-like domain DUF1308 PF07000.11 CRJ80037.1 - 4e-05 23.6 0.0 0.00023 21.1 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1308) DUF5614 PF18474.1 CRJ80037.1 - 0.0024 17.3 0.1 0.0048 16.2 0.1 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5614) LacAB_rpiB PF02502.18 CRJ80043.1 - 1.5e-43 148.1 0.1 1.7e-43 148.0 0.1 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase DUF1688 PF07958.11 CRJ80047.1 - 5.5e-181 601.9 0.0 6.4e-181 601.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) TOM13 PF08219.11 CRJ80052.1 - 1.4e-36 124.3 0.0 3.6e-36 123.0 0.0 1.7 1 0 0 1 1 1 1 Outer membrane protein TOM13 60KD_IMP PF02096.20 CRJ80052.1 - 1.4e-22 80.4 5.7 1.9e-22 79.9 5.7 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein SEP PF08059.13 CRJ80058.1 - 3.5e-24 85.1 0.0 3.7e-23 81.9 0.0 2.4 2 0 0 2 2 2 1 SEP domain UBX PF00789.20 CRJ80058.1 - 1.1e-09 38.4 0.0 1.8e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 CRJ80058.1 - 8.2e-09 35.2 0.7 1.3e-08 34.5 0.7 1.3 1 0 0 1 1 1 1 UBA-like domain TAP_C PF03943.13 CRJ80058.1 - 0.0018 17.9 0.0 0.003 17.2 0.0 1.3 1 0 0 1 1 1 1 TAP C-terminal domain SWIRM-assoc_2 PF16496.5 CRJ80058.1 - 0.35 9.7 1.0 0.46 9.3 1.0 1.2 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Gtr1_RagA PF04670.12 CRJ80062.1 - 1.2e-92 309.4 0.0 1.6e-92 309.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 CRJ80062.1 - 8.4e-08 32.5 0.0 1.7e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CRJ80062.1 - 1.1e-07 31.7 0.0 1.8e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Ras family Arf PF00025.21 CRJ80062.1 - 2.6e-07 30.3 0.0 3.6e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CRJ80062.1 - 2.7e-07 30.7 0.0 4.6e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 CRJ80062.1 - 0.00066 18.9 2.9 0.38 9.9 0.7 2.8 2 1 1 3 3 3 2 G-protein alpha subunit AAA_29 PF13555.6 CRJ80062.1 - 0.0028 17.4 0.7 0.038 13.7 0.2 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF815 PF05673.13 CRJ80062.1 - 0.0036 16.5 0.0 0.0077 15.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RsgA_GTPase PF03193.16 CRJ80062.1 - 0.0066 16.4 0.2 0.25 11.2 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 CRJ80062.1 - 0.0068 16.9 0.2 0.013 16.0 0.1 1.6 1 1 0 1 1 1 1 ABC transporter AAA_7 PF12775.7 CRJ80062.1 - 0.034 13.7 0.0 0.55 9.7 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 CRJ80062.1 - 0.16 11.7 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Sugar_tr PF00083.24 CRJ80067.1 - 2.2e-78 264.1 21.6 2.5e-78 263.9 21.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRJ80067.1 - 5e-30 104.6 22.3 8.7e-28 97.3 15.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 CRJ80067.1 - 1e-05 25.1 0.6 1e-05 25.1 0.6 1.8 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB YrhK PF14145.6 CRJ80067.1 - 0.12 12.3 3.8 0.12 12.2 0.9 2.6 2 0 0 2 2 2 0 YrhK-like protein OATP PF03137.20 CRJ80067.1 - 1.8 6.7 14.9 1.1 7.4 0.3 3.8 4 1 1 5 5 5 0 Organic Anion Transporter Polypeptide (OATP) family RPE65 PF03055.15 CRJ80072.1 - 4.5e-103 345.9 0.0 5.2e-103 345.7 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein VSP PF03302.13 CRJ80077.1 - 0.0062 15.4 0.8 0.011 14.7 0.8 1.4 1 0 0 1 1 1 1 Giardia variant-specific surface protein Podoplanin PF05808.11 CRJ80077.1 - 0.014 15.5 0.3 0.086 12.9 0.1 2.3 2 0 0 2 2 2 0 Podoplanin SKG6 PF08693.10 CRJ80077.1 - 0.023 14.1 3.7 0.06 12.8 3.7 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain PEP-CTERM PF07589.11 CRJ80077.1 - 0.27 11.4 3.1 0.74 10.0 3.1 1.8 1 0 0 1 1 1 0 PEP-CTERM motif GT87 PF09594.10 CRJ80077.1 - 0.5 10.0 5.3 0.78 9.4 5.3 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 87 TMEM154 PF15102.6 CRJ80077.1 - 7.9 6.4 6.0 85 3.0 7.4 2.0 2 0 0 2 2 2 0 TMEM154 protein family DJ-1_PfpI PF01965.24 CRJ80081.1 - 1.2e-12 48.0 0.0 2.5e-12 46.9 0.0 1.7 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 CRJ80081.1 - 2.5e-07 30.6 0.0 1.2e-06 28.4 0.0 1.9 1 1 0 1 1 1 1 ThiJ/PfpI family-like Sugar_tr PF00083.24 CRJ80085.1 - 6.8e-96 321.9 18.7 8.7e-96 321.5 18.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRJ80085.1 - 3e-19 69.2 34.5 5e-19 68.4 30.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_3_2 PF04550.12 CRJ80085.1 - 0.18 12.3 3.2 0.15 12.6 0.6 2.3 2 0 0 2 2 2 0 Phage holin family 2 FAD_binding_3 PF01494.19 CRJ80096.1 - 4.5e-15 55.7 0.0 7.9e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 CRJ80096.1 - 3.7e-12 46.5 3.6 2e-05 24.3 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CRJ80096.1 - 1.4e-11 44.2 0.1 4.9e-07 29.3 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CRJ80096.1 - 6.1e-10 38.7 0.4 1.9e-09 37.1 0.4 1.7 1 1 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.14 CRJ80096.1 - 3.2e-09 36.2 0.7 2.1e-05 23.6 1.2 2.1 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_2 PF00890.24 CRJ80096.1 - 2.5e-07 30.1 1.5 5.5e-07 29.0 1.5 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 CRJ80096.1 - 1.7e-06 27.0 0.5 5e-05 22.2 0.2 2.1 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 CRJ80096.1 - 2.8e-06 27.4 0.6 7.4e-06 26.1 0.6 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 CRJ80096.1 - 1.5e-05 24.5 1.7 0.048 12.9 0.2 2.6 2 1 1 3 3 3 2 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 CRJ80096.1 - 8.3e-05 23.1 1.0 0.0013 19.2 0.7 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CRJ80096.1 - 0.00015 21.0 1.0 0.00024 20.3 1.0 1.4 1 1 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_9 PF13454.6 CRJ80096.1 - 0.0012 18.8 1.7 0.005 16.8 1.7 2.0 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 CRJ80096.1 - 0.0019 17.5 1.5 0.0098 15.2 1.3 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CRJ80096.1 - 0.0026 17.2 4.6 0.0085 15.5 3.2 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 CRJ80096.1 - 0.0055 16.0 0.2 0.01 15.2 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 CRJ80096.1 - 0.0089 15.3 0.2 0.015 14.6 0.2 1.3 1 0 0 1 1 1 1 Thi4 family ApbA PF02558.16 CRJ80096.1 - 0.027 14.1 1.2 0.054 13.1 1.2 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 CRJ80096.1 - 0.032 13.8 0.1 0.05 13.2 0.1 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 CRJ80096.1 - 0.1 12.5 0.3 0.18 11.6 0.3 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CsbD PF05532.12 CRJ80100.1 - 3.3e-08 33.3 6.3 0.00031 20.6 0.2 2.2 2 0 0 2 2 2 2 CsbD-like TAF6_C PF07571.13 CRJ80105.1 - 8.2e-28 96.6 0.0 2e-27 95.3 0.0 1.7 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 CRJ80105.1 - 4.6e-21 74.7 0.1 9.8e-21 73.7 0.1 1.6 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.13 CRJ80105.1 - 0.0019 18.1 0.0 0.0041 17.1 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.24 CRJ80105.1 - 0.0093 16.3 0.2 0.015 15.7 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CRJ80105.1 - 0.15 12.3 0.0 0.35 11.2 0.0 1.6 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Sdh_cyt PF01127.22 CRJ80108.1 - 7.3e-17 61.5 4.0 9.5e-17 61.2 4.0 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit TauD PF02668.16 CRJ80111.1 - 3.2e-42 145.2 0.2 4.9e-42 144.6 0.2 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DAG1 PF05454.11 CRJ80111.1 - 0.25 10.7 0.0 0.25 10.7 0.0 1.7 2 0 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Helicase_C PF00271.31 CRJ80114.1 - 2.9e-33 114.5 0.0 4.9e-33 113.8 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CRJ80114.1 - 7e-21 74.8 0.0 1.4e-20 73.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase TniB PF05621.11 CRJ80114.1 - 0.044 13.2 0.0 0.084 12.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein tRNA-synt_1b PF00579.25 CRJ80114.1 - 0.15 11.3 0.0 0.34 10.2 0.0 1.5 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) PLU-1 PF08429.11 CRJ80116.1 - 2.9e-112 375.2 13.1 2.4e-109 365.6 10.3 2.4 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.22 CRJ80116.1 - 9.6e-43 145.2 0.2 2.1e-42 144.2 0.2 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase SF3A3 PF16837.5 CRJ80116.1 - 1.8e-24 86.0 1.2 4.5e-24 84.8 0.4 2.2 2 0 0 2 2 1 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 ARID PF01388.21 CRJ80116.1 - 4.9e-21 75.2 0.1 1.6e-20 73.6 0.1 2.0 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PHD PF00628.29 CRJ80116.1 - 6.2e-16 58.0 32.9 2.9e-09 36.7 7.1 4.2 4 0 0 4 4 4 2 PHD-finger JmjN PF02375.17 CRJ80116.1 - 2.4e-14 53.0 1.5 7.3e-14 51.4 1.5 1.9 1 0 0 1 1 1 1 jmjN domain SF3a60_bindingd PF12108.8 CRJ80116.1 - 1.7e-12 47.0 0.1 3.8e-12 45.9 0.1 1.7 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-C5HC2 PF02928.16 CRJ80116.1 - 1.1e-11 44.9 5.1 3.5e-11 43.3 5.1 1.9 1 0 0 1 1 1 1 C5HC2 zinc finger zf-C2H2_jaz PF12171.8 CRJ80116.1 - 5.3e-06 26.6 1.2 5.3e-06 26.6 1.2 3.6 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CRJ80116.1 - 4.1e-05 23.8 1.0 4.1e-05 23.8 1.0 3.2 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-HC5HC2H_2 PF13832.6 CRJ80116.1 - 0.015 15.5 7.5 0.091 12.9 1.5 2.7 2 0 0 2 2 2 0 PHD-zinc-finger like domain KIX PF02172.16 CRJ80116.1 - 0.043 14.1 0.0 0.14 12.4 0.0 1.9 1 0 0 1 1 1 0 KIX domain PRP9_N PF16958.5 CRJ80116.1 - 0.22 11.5 13.1 0.17 11.9 1.4 3.4 2 1 1 3 3 3 0 Pre-mRNA-splicing factor PRP9 N-terminus DUF3449 PF11931.8 CRJ80116.1 - 0.25 11.1 1.5 0.73 9.6 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) zf-PHD-like PF15446.6 CRJ80116.1 - 1.5 8.4 14.8 0.24 11.0 1.8 3.2 3 0 0 3 3 3 0 PHD/FYVE-zinc-finger like domain zf-RING_2 PF13639.6 CRJ80116.1 - 2.5 8.5 22.6 3.2 8.2 7.8 3.0 2 0 0 2 2 2 0 Ring finger domain zf-U1 PF06220.12 CRJ80116.1 - 5.5 6.9 8.2 1.6 8.6 0.5 2.8 2 0 0 2 2 2 0 U1 zinc finger DIOX_N PF14226.6 CRJ80120.1 - 6.6e-24 84.9 0.0 1.2e-23 84.1 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 CRJ80120.1 - 1.4e-20 73.7 0.0 4.1e-20 72.1 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Rieske PF00355.26 CRJ80120.1 - 9.5e-08 31.9 0.0 2.2e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 CRJ80120.1 - 4e-05 23.5 0.0 7.9e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Oxidored_FMN PF00724.20 CRJ80129.1 - 5.6e-87 292.2 0.0 8.9e-87 291.5 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Sec31 PF11549.8 CRJ80129.1 - 0.096 12.6 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein transport protein SEC31 Glyco_hydro_43 PF04616.14 CRJ80133.1 - 1.7e-104 349.2 0.8 4.9e-104 347.7 0.4 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 CRJ80133.1 - 1.1e-44 152.6 0.0 1.6e-44 152.0 0.0 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain DUF1349 PF07081.11 CRJ80133.1 - 0.019 14.7 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1349) E1-E2_ATPase PF00122.20 CRJ80137.1 - 5.1e-33 114.1 18.8 2.6e-28 98.8 0.2 3.8 5 0 0 5 5 5 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 CRJ80137.1 - 2.7e-29 102.1 2.8 2.7e-29 102.1 2.8 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 CRJ80137.1 - 7.3e-21 74.1 0.0 2e-20 72.7 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CRJ80137.1 - 7.6e-21 75.4 0.3 1.3e-16 61.6 0.1 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CRJ80137.1 - 1.7e-16 59.7 0.1 3.6e-16 58.6 0.1 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CRJ80137.1 - 2.8e-06 27.3 0.5 0.00026 20.8 0.5 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase SRP54 PF00448.22 CRJ80142.1 - 1e-70 237.4 2.8 1.7e-70 236.7 1.7 1.8 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain p450 PF00067.22 CRJ80142.1 - 1.2e-54 185.9 0.0 2.1e-54 185.0 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 SRP_SPB PF02978.19 CRJ80142.1 - 4.3e-30 104.3 5.8 4.3e-30 104.3 5.8 3.6 3 1 1 4 4 3 1 Signal peptide binding domain Peptidase_M14 PF00246.24 CRJ80142.1 - 8.7e-28 97.9 0.9 1.6e-27 97.1 0.9 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase SRP54_N PF02881.19 CRJ80142.1 - 1.4e-19 70.1 0.2 3.1e-19 69.0 0.2 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_33 PF13671.6 CRJ80142.1 - 5.5e-06 26.6 0.0 1.2e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 CRJ80142.1 - 1.1e-05 25.1 0.7 3.5e-05 23.5 0.7 1.8 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 CRJ80142.1 - 7.8e-05 23.1 0.1 0.00024 21.6 0.1 1.8 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 CRJ80142.1 - 0.00056 19.0 1.2 0.0031 16.5 1.2 2.1 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 CRJ80142.1 - 0.0018 18.7 0.0 0.0041 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 CRJ80142.1 - 0.0036 16.6 0.0 0.007 15.7 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_30 PF13604.6 CRJ80142.1 - 0.0045 16.7 0.1 0.012 15.3 0.1 1.7 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.20 CRJ80142.1 - 0.0065 16.4 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase ATP_bind_1 PF03029.17 CRJ80142.1 - 0.0083 15.9 0.4 0.13 12.0 0.0 2.5 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Thymidylate_kin PF02223.17 CRJ80142.1 - 0.011 15.5 0.6 0.023 14.4 0.1 1.9 2 0 0 2 2 1 0 Thymidylate kinase AAA_18 PF13238.6 CRJ80142.1 - 0.02 15.5 0.0 0.054 14.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CRJ80142.1 - 0.025 14.9 0.0 0.063 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 CRJ80142.1 - 0.038 14.1 0.0 0.089 12.9 0.0 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.14 CRJ80142.1 - 0.045 13.6 0.0 0.099 12.5 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.23 CRJ80142.1 - 0.054 13.6 0.1 0.17 12.0 0.1 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase ResIII PF04851.15 CRJ80142.1 - 0.06 13.3 0.3 0.17 11.9 0.3 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_19 PF13245.6 CRJ80142.1 - 0.097 13.0 0.1 0.24 11.7 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 CRJ80142.1 - 0.098 12.9 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain 6PF2K PF01591.18 CRJ80142.1 - 0.19 11.0 0.0 0.34 10.2 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase SRPRB PF09439.10 CRJ80142.1 - 0.21 11.0 0.7 11 5.4 0.9 2.8 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit SKA2 PF16740.5 CRJ80142.1 - 4.9 7.0 5.5 38 4.1 1.7 2.6 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Cys_Met_Meta_PP PF01053.20 CRJ80147.1 - 1.8e-117 392.1 0.0 2.1e-117 391.9 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 CRJ80147.1 - 3e-10 39.8 0.0 4.5e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 CRJ80147.1 - 4.4e-09 36.1 0.4 7e-09 35.5 0.1 1.4 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 CRJ80147.1 - 7.7e-09 35.0 0.1 1.2e-08 34.4 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-V GDC-P PF02347.16 CRJ80147.1 - 0.0053 15.6 0.0 0.0075 15.2 0.0 1.1 1 0 0 1 1 1 1 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 CRJ80147.1 - 0.0085 15.4 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase BRK PF07533.16 CRJ80147.1 - 0.017 14.7 0.5 1.5 8.5 0.1 3.4 4 0 0 4 4 4 0 BRK domain ADH_zinc_N PF00107.26 CRJ80147.1 - 0.019 15.0 0.0 0.054 13.5 0.0 1.8 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ATPgrasp_N PF18130.1 CRJ80151.1 - 1.5e-12 47.9 0.0 4.3e-12 46.4 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp N-terminal domain ATP-grasp_4 PF13535.6 CRJ80151.1 - 2.9e-10 40.0 0.0 6.7e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 CRJ80151.1 - 0.00019 21.1 0.0 0.00065 19.3 0.0 1.8 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.17 CRJ80151.1 - 0.0028 17.2 0.0 0.0056 16.2 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.14 CRJ80151.1 - 0.19 11.8 0.0 0.35 10.9 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain Ferric_reduct PF01794.19 CRJ80155.1 - 4.3e-21 75.3 11.4 4.3e-21 75.3 11.4 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 CRJ80155.1 - 2.1e-16 60.5 0.0 3.4e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 CRJ80155.1 - 1.4e-09 38.0 0.0 3.5e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 CRJ80155.1 - 0.002 18.7 0.0 0.0043 17.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Ctr PF04145.15 CRJ80159.1 - 1.1e-29 103.9 2.2 1.4e-29 103.6 2.2 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Oxidored_q3 PF00499.20 CRJ80159.1 - 0.024 14.3 2.3 0.024 14.3 2.3 2.0 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 NAS PF03059.16 CRJ80163.1 - 4.5e-20 72.1 0.0 6e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 Nicotianamine synthase protein Methyltransf_25 PF13649.6 CRJ80163.1 - 0.0085 16.8 0.0 0.019 15.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain ABC_membrane PF00664.23 CRJ80167.1 - 1.4e-49 169.2 31.9 3.1e-27 95.9 11.8 3.6 3 1 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 CRJ80167.1 - 3.8e-49 166.7 0.2 1.4e-26 93.6 0.0 3.0 3 0 0 3 3 2 2 ABC transporter MMR_HSR1 PF01926.23 CRJ80167.1 - 1.4e-06 28.3 1.7 0.034 14.2 0.1 3.1 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_16 PF13191.6 CRJ80167.1 - 5.4e-06 26.9 0.1 0.037 14.4 0.0 3.0 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 CRJ80167.1 - 5.5e-05 22.8 1.2 0.35 10.7 0.2 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 CRJ80167.1 - 8.9e-05 22.0 2.4 1.9 7.8 0.1 4.2 2 2 2 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CRJ80167.1 - 0.00016 21.6 1.6 0.76 9.5 0.0 3.7 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 CRJ80167.1 - 0.00024 21.1 1.0 0.17 11.7 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase NB-ARC PF00931.22 CRJ80167.1 - 0.00025 20.3 0.3 0.22 10.7 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain AAA_22 PF13401.6 CRJ80167.1 - 0.0007 19.9 0.6 3.7 7.8 0.0 3.4 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.6 CRJ80167.1 - 0.0013 19.3 0.3 0.78 10.2 0.4 2.3 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CRJ80167.1 - 0.003 17.9 0.1 0.16 12.4 0.0 2.5 2 0 0 2 2 2 1 RNA helicase Zeta_toxin PF06414.12 CRJ80167.1 - 0.0043 16.4 0.2 0.68 9.2 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin Dynamin_N PF00350.23 CRJ80167.1 - 0.0045 17.1 2.2 0.21 11.6 0.3 2.5 2 0 0 2 2 2 1 Dynamin family AAA_25 PF13481.6 CRJ80167.1 - 0.0067 16.0 0.0 0.61 9.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 CRJ80167.1 - 0.013 14.5 0.6 0.23 10.4 0.1 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_7 PF12775.7 CRJ80167.1 - 0.015 14.8 0.3 2.6 7.5 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_30 PF13604.6 CRJ80167.1 - 0.031 14.0 0.4 1.4 8.6 0.1 2.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 CRJ80167.1 - 0.048 13.6 0.2 2.1 8.2 0.0 2.6 2 0 0 2 2 2 0 NACHT domain DUF87 PF01935.17 CRJ80167.1 - 0.057 13.5 5.2 0.18 11.9 0.5 2.6 3 0 0 3 3 2 0 Helicase HerA, central domain AAA_18 PF13238.6 CRJ80167.1 - 0.063 13.8 0.4 23 5.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 CRJ80167.1 - 0.089 13.0 1.2 1.4 9.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 CRJ80167.1 - 0.14 11.7 0.8 16 5.0 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.7 CRJ80167.1 - 0.17 10.7 0.8 1.2 8.0 0.1 2.2 2 0 0 2 2 2 0 AAA-like domain ATP-synt_ab PF00006.25 CRJ80167.1 - 0.17 11.5 0.2 1.4 8.5 0.1 2.1 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_15 PF13175.6 CRJ80167.1 - 0.18 11.5 0.1 3.7 7.1 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain dNK PF01712.19 CRJ80167.1 - 0.28 11.0 0.4 5.4 6.8 0.0 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase NAD_binding_10 PF13460.6 CRJ80172.1 - 7.1e-32 110.8 0.3 8.5e-32 110.5 0.3 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 CRJ80172.1 - 2.5e-05 23.9 0.0 4e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 CRJ80172.1 - 0.12 11.5 0.0 0.22 10.7 0.0 1.5 2 0 0 2 2 2 0 Male sterility protein p450 PF00067.22 CRJ80175.1 - 2.1e-48 165.2 0.0 4.7e-48 164.1 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Lactamase_B PF00753.27 CRJ80179.1 - 2.2e-19 70.2 0.2 4.4e-19 69.3 0.2 1.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CRJ80179.1 - 3.2e-05 23.5 0.0 5.3e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Glyco_hydro_53 PF07745.13 CRJ80183.1 - 2.6e-98 329.2 0.0 3.2e-98 328.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 dCMP_cyt_deam_1 PF00383.23 CRJ80183.1 - 1.2e-12 47.5 0.1 2.2e-12 46.7 0.1 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CRJ80183.1 - 1.4e-06 28.1 0.0 1.2e-05 25.1 0.0 2.2 1 1 0 1 1 1 1 MafB19-like deaminase CBM_1 PF00734.18 CRJ80187.1 - 2.1e-12 46.8 18.4 6.2e-12 45.3 18.4 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain Sortilin-Vps10 PF15902.5 CRJ80187.1 - 5.5e-11 41.9 5.3 0.012 14.4 0.0 4.5 3 2 1 4 4 4 4 Sortilin, neurotensin receptor 3, Toxin_7 PF05980.12 CRJ80187.1 - 0.033 14.4 3.4 0.057 13.7 3.4 1.3 1 0 0 1 1 1 0 Toxin 7 Kelch_1 PF01344.25 CRJ80187.1 - 0.064 12.9 0.2 0.33 10.6 0.2 2.4 1 0 0 1 1 1 0 Kelch motif BNR PF02012.20 CRJ80187.1 - 0.072 13.1 37.8 0.18 11.9 0.0 9.7 9 0 0 9 9 9 0 BNR/Asp-box repeat BNR_2 PF13088.6 CRJ80187.1 - 5.6 6.2 9.1 13 4.9 0.2 4.0 3 1 1 4 4 4 0 BNR repeat-like domain DUF1749 PF08538.10 CRJ80192.1 - 3.2e-72 243.2 0.0 4e-72 242.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_1 PF00561.20 CRJ80192.1 - 0.0016 18.1 0.1 0.05 13.2 0.0 2.1 1 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CRJ80192.1 - 0.0026 17.1 0.0 0.029 13.6 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 CRJ80192.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold Ferric_reduct PF01794.19 CRJ80197.1 - 4.1e-19 68.9 15.1 4.1e-19 68.9 15.1 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 CRJ80197.1 - 2.1e-06 27.7 0.0 9.7e-06 25.6 0.0 2.1 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.12 CRJ80197.1 - 0.0058 16.8 0.0 1.9 8.6 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain Glyco_hydro_28 PF00295.17 CRJ80202.1 - 1.9e-08 33.7 0.1 2.6e-08 33.3 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 adh_short PF00106.25 CRJ80208.1 - 4.5e-28 98.0 1.2 2e-25 89.4 0.3 2.4 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CRJ80208.1 - 6.7e-17 61.8 0.5 7.6e-15 55.1 0.5 2.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRJ80208.1 - 1e-05 25.6 0.2 1.8e-05 24.7 0.2 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CRJ80208.1 - 0.0022 17.5 0.1 0.0035 16.8 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Peptidase_C42 PF05533.12 CRJ80208.1 - 0.15 12.1 0.0 1.9 8.6 0.0 2.6 3 0 0 3 3 3 0 Beet yellows virus-type papain-like endopeptidase C42 Sulfate_transp PF00916.20 CRJ80211.1 - 1.3e-109 366.4 19.9 1.7e-109 366.1 19.9 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 CRJ80211.1 - 1.4e-06 28.0 0.0 2.8e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 CRJ80211.1 - 2.4e-05 24.7 3.8 2.4e-05 24.7 3.8 3.5 3 2 1 4 4 4 2 Molybdate transporter of MFS superfamily YdjM PF04307.14 CRJ80211.1 - 0.00072 18.9 0.0 0.0043 16.4 0.0 2.3 1 1 0 2 2 2 1 LexA-binding, inner membrane-associated putative hydrolase CVNH PF08881.10 CRJ80219.1 - 1.2e-09 38.8 0.1 2.1e-09 38.0 0.0 1.5 1 1 0 1 1 1 1 CVNH domain WRC PF08879.10 CRJ80219.1 - 0.0042 16.8 0.6 0.0092 15.7 0.6 1.6 1 0 0 1 1 1 1 WRC MAR_sialic_bdg PF10564.9 CRJ80219.1 - 0.023 14.7 0.4 0.038 14.0 0.4 1.4 1 0 0 1 1 1 0 Sialic-acid binding micronemal adhesive repeat His_Phos_1 PF00300.22 CRJ80223.1 - 1.1e-25 90.4 0.1 4.6e-25 88.5 0.1 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) ERCC4 PF02732.15 CRJ80228.1 - 1.2e-25 90.5 0.0 2e-25 89.8 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain eIF3_subunit PF08597.10 CRJ80228.1 - 3.1 7.6 24.5 0.21 11.5 18.8 1.9 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit Presenilin PF01080.17 CRJ80228.1 - 8.2 5.1 9.1 2.9 6.6 6.0 1.7 2 0 0 2 2 2 0 Presenilin CPSF100_C PF13299.6 CRJ80228.1 - 8.9 6.5 10.1 21 5.2 7.9 2.4 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Kinesin PF00225.23 CRJ80231.1 - 6.9e-157 521.6 7.3 4.3e-90 302.0 0.0 3.9 3 0 0 3 3 3 2 Kinesin motor domain Microtub_bd PF16796.5 CRJ80231.1 - 1.2e-21 77.2 0.0 4.8e-16 59.0 0.0 4.5 2 1 0 3 3 3 3 Microtubule binding Titin_Ig-rpts PF06582.12 CRJ80231.1 - 3.4 7.7 6.4 2.1e+02 1.9 0.2 5.0 4 0 0 4 4 4 0 Titin repeat DNA_binding_1 PF01035.20 CRJ80236.1 - 1.1e-25 89.5 0.1 1.5e-25 89.1 0.1 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain DUF4224 PF13986.6 CRJ80236.1 - 0.017 15.0 0.1 0.18 11.7 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4224) Tropomyosin PF00261.20 CRJ80240.1 - 7.5e-05 22.2 12.4 0.00011 21.6 12.4 1.2 1 0 0 1 1 1 1 Tropomyosin Tropomyosin_1 PF12718.7 CRJ80240.1 - 0.00015 21.9 17.0 0.00024 21.3 14.1 2.0 2 0 0 2 2 2 1 Tropomyosin like DUF1664 PF07889.12 CRJ80240.1 - 0.00016 21.7 3.6 0.00016 21.7 3.6 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) HR1 PF02185.16 CRJ80240.1 - 0.0021 18.1 0.7 0.0021 18.1 0.7 2.7 2 0 0 2 2 2 1 Hr1 repeat Filament PF00038.21 CRJ80240.1 - 0.0067 16.1 3.1 0.0067 16.1 3.1 2.3 3 0 0 3 3 3 1 Intermediate filament protein Fib_alpha PF08702.10 CRJ80240.1 - 0.012 15.8 0.4 0.012 15.8 0.4 1.9 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family HALZ PF02183.18 CRJ80240.1 - 0.022 15.0 3.9 2.8 8.2 1.1 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper Spc29 PF17082.5 CRJ80240.1 - 0.055 13.3 4.9 0.13 12.1 4.9 1.6 1 1 0 1 1 1 0 Spindle Pole Component 29 GLTP PF08718.11 CRJ80240.1 - 0.078 13.3 0.2 0.17 12.2 0.2 1.5 1 0 0 1 1 1 0 Glycolipid transfer protein (GLTP) Peptidase_S46 PF10459.9 CRJ80240.1 - 0.098 11.3 3.9 0.12 11.0 3.9 1.1 1 0 0 1 1 1 0 Peptidase S46 DUF16 PF01519.16 CRJ80240.1 - 0.43 11.1 8.5 0.066 13.7 3.6 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF16 Exonuc_VII_L PF02601.15 CRJ80240.1 - 0.46 10.0 7.3 0.55 9.7 7.3 1.3 1 1 0 1 1 1 0 Exonuclease VII, large subunit MutS_III PF05192.18 CRJ80240.1 - 0.51 10.5 4.3 0.4 10.9 2.8 1.6 2 0 0 2 2 1 0 MutS domain III Plk4_PB2 PF18409.1 CRJ80240.1 - 0.55 11.0 2.9 0.6 10.8 1.5 1.7 1 1 1 2 2 1 0 Polo-like Kinase 4 Polo Box 2 SKA2 PF16740.5 CRJ80240.1 - 0.56 10.0 15.4 3.6 7.4 6.9 3.6 3 1 0 3 3 3 0 Spindle and kinetochore-associated protein 2 Elongin_A PF06881.11 CRJ80240.1 - 0.58 10.7 16.1 0.14 12.7 12.2 2.0 2 1 1 3 3 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A PhaP_Bmeg PF09602.10 CRJ80240.1 - 0.58 10.1 8.4 0.12 12.3 3.7 2.1 2 0 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Lectin_N PF03954.14 CRJ80240.1 - 0.69 9.7 4.5 1 9.1 2.6 2.1 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain MscS_porin PF12795.7 CRJ80240.1 - 0.84 9.1 19.2 0.27 10.7 14.6 2.3 2 1 0 2 2 2 0 Mechanosensitive ion channel porin domain DUF3584 PF12128.8 CRJ80240.1 - 1.1 6.6 14.7 1.8 6.0 14.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) GCN5L1 PF06320.13 CRJ80240.1 - 1.2 9.4 12.3 0.054 13.6 3.0 2.5 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) APG6_N PF17675.1 CRJ80240.1 - 1.4 9.5 18.0 0.054 14.0 5.2 2.4 3 0 0 3 3 2 0 Apg6 coiled-coil region GAS PF13851.6 CRJ80240.1 - 1.6 8.1 15.8 0.037 13.4 4.3 2.8 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding SlyX PF04102.12 CRJ80240.1 - 1.6 9.4 16.1 0.24 12.0 4.1 3.6 3 1 1 4 4 4 0 SlyX DUF4298 PF14131.6 CRJ80240.1 - 1.6 8.7 9.4 1.5 8.8 3.9 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4298) FAM184 PF15665.5 CRJ80240.1 - 2.7 7.7 15.3 0.11 12.2 6.6 2.2 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B Lzipper-MIP1 PF14389.6 CRJ80240.1 - 2.8 8.3 10.8 1.4 9.3 6.4 2.5 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 V_ATPase_I PF01496.19 CRJ80240.1 - 2.8 5.8 4.3 3.7 5.3 4.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family YabA PF06156.13 CRJ80240.1 - 2.9 8.6 7.4 2.1 9.1 3.3 2.6 2 1 0 2 2 2 0 Initiation control protein YabA P4Ha_N PF08336.11 CRJ80240.1 - 3.1 7.8 7.5 0.13 12.3 0.6 2.2 3 0 0 3 3 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Fez1 PF06818.15 CRJ80240.1 - 3.6 8.0 16.9 0.64 10.4 13.3 1.5 2 0 0 2 2 1 0 Fez1 ARD PF03079.14 CRJ80240.1 - 4.2 7.5 6.6 0.65 10.2 1.9 1.8 1 1 1 2 2 2 0 ARD/ARD' family CCDC-167 PF15188.6 CRJ80240.1 - 4.2 7.8 12.6 0.5 10.7 1.4 2.5 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Flagellin_N PF00669.20 CRJ80240.1 - 4.3 7.5 7.9 0.41 10.8 1.1 2.3 3 0 0 3 3 2 0 Bacterial flagellin N-terminal helical region RR_TM4-6 PF06459.12 CRJ80240.1 - 4.5 7.0 8.6 6.2 6.6 8.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SKA1 PF07160.12 CRJ80240.1 - 4.8 7.0 12.6 1.6 8.5 10.0 1.4 2 0 0 2 2 1 0 Spindle and kinetochore-associated protein 1 Prefoldin_2 PF01920.20 CRJ80240.1 - 5.3 7.0 18.8 0.065 13.2 2.8 3.5 3 1 1 4 4 4 0 Prefoldin subunit Golgin_A5 PF09787.9 CRJ80240.1 - 5.4 6.4 15.9 1.2 8.5 12.7 1.4 2 0 0 2 2 2 0 Golgin subfamily A member 5 BST2 PF16716.5 CRJ80240.1 - 5.7 7.6 14.6 0.35 11.5 6.1 2.6 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 TMPIT PF07851.13 CRJ80240.1 - 6.6 5.9 10.4 1.6 7.9 7.4 1.5 2 0 0 2 2 2 0 TMPIT-like protein Lebercilin PF15619.6 CRJ80240.1 - 7.1 6.2 21.2 0.17 11.5 7.3 2.5 3 0 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease DUF4472 PF14739.6 CRJ80240.1 - 7.7 7.3 16.6 4.7 8.0 4.5 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4472) DNA_binding_1 PF01035.20 CRJ80244.1 - 4.8e-48 161.2 1.7 1.2e-24 86.3 0.1 2.5 2 1 0 2 2 2 2 6-O-methylguanine DNA methyltransferase, DNA binding domain DUF4224 PF13986.6 CRJ80244.1 - 0.00093 19.0 0.4 0.58 10.1 0.0 3.2 4 0 0 4 4 4 2 Domain of unknown function (DUF4224) DUF4350 PF14258.6 CRJ80244.1 - 0.0048 17.3 0.4 1.1 9.8 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4350) T6SS_VasE PF05936.12 CRJ80244.1 - 0.0093 14.7 2.2 1.5 7.5 0.1 2.1 2 0 0 2 2 2 2 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE APH PF01636.23 CRJ80250.1 - 2.9e-15 56.8 0.0 1.5e-08 34.8 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.20 CRJ80250.1 - 2.1e-07 30.8 0.0 6.2e-07 29.2 0.0 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.14 CRJ80250.1 - 0.0013 18.0 0.0 0.0024 17.1 0.0 1.4 1 0 0 1 1 1 1 Fructosamine kinase Pkinase PF00069.25 CRJ80250.1 - 0.0081 15.6 0.0 0.22 10.9 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRJ80250.1 - 0.019 14.3 0.0 0.16 11.3 0.0 2.0 2 0 0 2 2 2 0 Protein tyrosine kinase DUF1679 PF07914.11 CRJ80250.1 - 0.043 12.7 0.0 2.7 6.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) ALIX_LYPXL_bnd PF13949.6 CRJ80257.1 - 6.2e-60 203.0 0.3 8.8e-60 202.5 0.3 1.1 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV APH PF01636.23 CRJ80257.1 - 1.2e-06 28.7 1.9 0.069 13.1 0.0 3.1 2 1 1 3 3 3 2 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 CRJ80257.1 - 0.0088 15.3 0.0 0.019 14.2 0.0 1.5 1 0 0 1 1 1 1 Fructosamine kinase Com_YlbF PF06133.11 CRJ80257.1 - 0.44 11.2 5.5 0.18 12.4 2.1 2.1 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA BRO1 PF03097.18 CRJ80264.1 - 3.7e-245 812.8 0.0 1.4e-121 406.0 0.0 2.3 2 0 0 2 2 2 2 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 CRJ80264.1 - 5.8e-108 360.7 8.9 1.5e-52 178.7 0.0 4.0 2 1 1 3 3 3 3 ALIX V-shaped domain binding to HIV Glyco_hyd_65N_2 PF14498.6 CRJ80264.1 - 7e-22 78.4 0.0 1.2e-21 77.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Lysyl_oxidase PF01186.17 CRJ80264.1 - 0.043 13.5 5.0 2.7 7.6 0.4 2.3 2 0 0 2 2 2 0 Lysyl oxidase DUF4734 PF15881.5 CRJ80264.1 - 0.056 13.6 0.2 22 5.3 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4734) Urotensin_II PF02083.15 CRJ80264.1 - 0.26 11.1 4.3 12 5.8 0.3 2.7 2 0 0 2 2 2 0 Urotensin II Sugar_tr PF00083.24 CRJ80271.1 - 4.7e-57 193.9 29.1 5.7e-57 193.6 29.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRJ80271.1 - 8.1e-31 107.2 45.4 1.2e-27 96.8 27.9 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hyd_65N_2 PF14498.6 CRJ80277.1 - 2.9e-56 191.0 0.0 3.9e-56 190.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain TraK PF06586.11 CRJ80277.1 - 0.081 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 TraK protein Sugar_tr PF00083.24 CRJ80280.1 - 6.8e-57 193.3 29.3 8.3e-57 193.0 29.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRJ80280.1 - 5.6e-32 111.0 43.9 8.8e-29 100.5 27.0 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_1 PF00232.18 CRJ80282.1 - 1.4e-133 445.6 0.3 1.7e-133 445.3 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 HPP PF04982.13 CRJ80285.1 - 3.1e-24 85.5 2.7 5.2e-24 84.8 2.7 1.3 1 0 0 1 1 1 1 HPP family RskA PF10099.9 CRJ80285.1 - 0.81 10.0 10.8 2.4 8.4 1.7 2.2 2 0 0 2 2 2 0 Anti-sigma-K factor rskA MIP PF00230.20 CRJ80294.1 - 6.6e-49 166.7 14.1 8.5e-49 166.3 14.1 1.1 1 0 0 1 1 1 1 Major intrinsic protein Bestrophin PF01062.21 CRJ80302.1 - 2.2e-33 115.9 0.0 3.9e-33 115.1 0.0 1.3 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel T6SS_VasE PF05936.12 CRJ80302.1 - 0.12 11.1 0.1 0.17 10.6 0.1 1.2 1 0 0 1 1 1 0 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE FAD_binding_8 PF08022.12 CRJ80306.1 - 1.9e-08 34.4 0.0 3.3e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 CRJ80306.1 - 2e-05 24.7 0.4 3.4e-05 24.0 0.4 1.4 1 0 0 1 1 1 1 Ferric reductase like transmembrane component LRR_3 PF07725.12 CRJ80306.1 - 0.0048 16.7 0.5 0.11 12.4 0.0 2.9 3 0 0 3 3 3 1 Leucine Rich Repeat Aldo_ket_red PF00248.21 CRJ80310.1 - 1.7e-49 168.6 0.0 3.4e-47 161.1 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Death PF00531.22 CRJ80310.1 - 0.0025 18.0 0.0 2.9 8.1 0.0 3.0 3 0 0 3 3 3 2 Death domain LysM PF01476.20 CRJ80310.1 - 0.031 14.4 0.1 0.059 13.5 0.1 1.4 1 0 0 1 1 1 0 LysM domain Band_7 PF01145.25 CRJ80314.1 - 2.8e-15 56.8 0.0 2.8e-15 56.8 0.0 3.2 3 2 1 4 4 4 1 SPFH domain / Band 7 family F-box-like PF12937.7 CRJ80317.1 - 6.1e-05 22.8 0.1 0.00017 21.4 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CRJ80317.1 - 0.00077 19.3 0.0 0.0017 18.2 0.0 1.7 1 0 0 1 1 1 1 F-box domain Glyoxalase_6 PF18029.1 CRJ80317.1 - 0.077 13.8 0.0 0.82 10.5 0.0 2.6 2 0 0 2 2 2 0 Glyoxalase-like domain MCD_N PF17408.2 CRJ80317.1 - 0.14 12.3 0.0 0.33 11.1 0.0 1.6 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase N-terminal domain PHO4 PF01384.20 CRJ80322.1 - 5e-99 331.5 13.5 6.4e-99 331.2 13.5 1.0 1 0 0 1 1 1 1 Phosphate transporter family Nodulin-like PF06813.13 CRJ80327.1 - 1.2e-05 25.0 1.1 0.042 13.3 0.5 2.3 2 0 0 2 2 2 2 Nodulin-like Fringe PF02434.16 CRJ80330.1 - 7.1e-09 35.5 0.0 1.4e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Fringe-like DUF604 PF04646.12 CRJ80330.1 - 0.00024 20.6 0.0 0.00054 19.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Ysc84 PF04366.12 CRJ80336.1 - 1.2e-46 157.6 0.1 1.9e-46 156.9 0.1 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator Fringe PF02434.16 CRJ80336.1 - 1.7e-08 34.2 0.0 3.5e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Fringe-like DUF604 PF04646.12 CRJ80336.1 - 0.00059 19.3 0.0 0.0012 18.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Ysc84 PF04366.12 CRJ80339.1 - 9.2e-51 170.9 0.1 1.7e-50 170.1 0.1 1.5 1 0 0 1 1 1 1 Las17-binding protein actin regulator FAD_binding_4 PF01565.23 CRJ80342.1 - 1e-18 67.4 0.5 1.9e-18 66.5 0.5 1.5 1 0 0 1 1 1 1 FAD binding domain GFO_IDH_MocA PF01408.22 CRJ80356.1 - 1.1e-22 81.1 1.4 1.3e-22 80.9 0.3 1.7 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 CRJ80356.1 - 2.4e-07 30.7 0.0 5.3e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 CRJ80356.1 - 0.00045 20.9 0.2 0.001 19.7 0.2 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain AAA_33 PF13671.6 CRJ80356.1 - 0.0026 17.9 0.0 0.011 15.9 0.0 1.9 1 1 1 2 2 2 1 AAA domain Semialdhyde_dh PF01118.24 CRJ80356.1 - 0.0089 16.5 0.1 0.019 15.4 0.1 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Zn_clus PF00172.18 CRJ80361.1 - 1.6e-05 24.9 6.4 2.9e-05 24.1 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 CRJ80361.1 - 0.0025 16.7 1.1 0.011 14.6 1.1 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain LHC PF00556.20 CRJ80361.1 - 0.25 11.6 1.2 0.64 10.3 1.2 1.7 1 0 0 1 1 1 0 Antenna complex alpha/beta subunit MnhB PF04039.13 CRJ80365.1 - 0.0014 18.9 3.3 0.0026 18.1 3.3 1.5 1 0 0 1 1 1 1 Domain related to MnhB subunit of Na+/H+ antiporter DUF4231 PF14015.6 CRJ80365.1 - 0.18 12.3 1.4 0.34 11.4 0.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) Peptidase_S41_N PF11918.8 CRJ80365.1 - 0.21 11.8 0.0 0.33 11.2 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain of Peptidase_S41 in eukaryotic IRBP KAR PF15222.6 CRJ80368.1 - 0.07 13.4 0.2 0.15 12.4 0.2 1.5 1 0 0 1 1 1 0 Kidney androgen-regulated Zn_clus PF00172.18 CRJ80368.1 - 0.11 12.6 15.4 0.22 11.6 15.4 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Pec_lyase_C PF00544.19 CRJ80371.1 - 1.4e-39 135.9 4.3 1.8e-39 135.5 4.3 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 CRJ80371.1 - 4e-09 36.5 4.2 8.2e-05 22.5 1.0 2.2 2 0 0 2 2 2 2 Right handed beta helix region ATXN-1_C PF12547.8 CRJ80371.1 - 0.02 15.2 0.8 0.038 14.3 0.8 1.5 1 0 0 1 1 1 0 Capicua transcriptional repressor modulator adh_short_C2 PF13561.6 CRJ80375.1 - 2.1e-53 181.3 0.0 2.6e-53 181.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRJ80375.1 - 1.9e-45 154.7 0.4 2.3e-45 154.5 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CRJ80375.1 - 2.3e-09 37.4 0.2 2.9e-09 37.1 0.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CRJ80375.1 - 0.01 15.3 0.1 0.018 14.5 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family PALP PF00291.25 CRJ80375.1 - 0.049 13.0 0.0 0.081 12.3 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Glyco_trans_4_4 PF13579.6 CRJ80375.1 - 0.064 13.7 0.1 7.1 7.0 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain THF_DHG_CYH_C PF02882.19 CRJ80375.1 - 0.079 12.3 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 CRJ80375.1 - 0.085 12.7 0.3 0.88 9.4 0.0 2.3 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MFS_1 PF07690.16 CRJ80380.1 - 1.3e-36 126.2 36.4 1.3e-36 126.2 36.4 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CRJ80380.1 - 3.2e-13 49.4 8.4 3.2e-13 49.4 8.4 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter DUF4112 PF13430.6 CRJ80380.1 - 0.064 13.5 1.0 1.1 9.6 0.1 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4112) Sugar_tr PF00083.24 CRJ80383.1 - 2.6e-109 366.1 20.6 3.1e-109 365.9 20.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRJ80383.1 - 1.9e-20 73.1 31.2 4.2e-14 52.2 7.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily HET PF06985.11 CRJ80390.1 - 1.1e-08 35.5 0.0 2.4e-06 27.9 0.0 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Tetraspanin PF00335.20 CRJ80397.1 - 0.0006 19.6 0.0 0.00084 19.1 0.0 1.2 1 0 0 1 1 1 1 Tetraspanin family TrbC PF04956.13 CRJ80397.1 - 4.2 7.7 7.6 14 6.0 2.4 2.2 2 0 0 2 2 2 0 TrbC/VIRB2 family Sugar_tr PF00083.24 CRJ80401.1 - 7.9e-57 193.1 23.6 5.8e-54 183.6 16.5 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CRJ80401.1 - 1.4e-11 43.9 37.8 1.8e-10 40.3 36.6 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_1 PF00232.18 CRJ80406.1 - 1.3e-129 432.6 0.0 1.6e-129 432.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 R3H PF01424.22 CRJ80406.1 - 0.12 12.4 0.4 0.28 11.2 0.4 1.6 1 0 0 1 1 1 0 R3H domain Cation_ATPase_C PF00689.21 CRJ80411.1 - 2.5e-44 151.2 7.8 3.9e-44 150.5 7.8 1.3 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 CRJ80411.1 - 6.6e-06 26.6 0.1 1.6e-05 25.3 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CRJ80411.1 - 0.0011 18.8 0.3 0.0016 18.2 0.3 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hepatitis_core PF00906.20 CRJ80411.1 - 0.68 9.4 0.0 0.68 9.4 0.0 2.0 2 0 0 2 2 2 0 Hepatitis core antigen E1-E2_ATPase PF00122.20 CRJ80413.1 - 3.2e-26 92.0 0.2 4.8e-26 91.4 0.2 1.3 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase PF13246.6 CRJ80413.1 - 1.1e-20 73.5 0.0 2.4e-20 72.4 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) LptF_LptG PF03739.14 CRJ80413.1 - 0.05 12.5 0.1 0.079 11.8 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG Pec_lyase_C PF00544.19 CRJ80419.1 - 1.4e-39 135.9 4.3 1.8e-39 135.5 4.3 1.1 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 CRJ80419.1 - 4e-09 36.5 4.2 8.2e-05 22.5 1.0 2.2 2 0 0 2 2 2 2 Right handed beta helix region ATXN-1_C PF12547.8 CRJ80419.1 - 0.0044 17.3 1.0 0.0082 16.4 1.0 1.5 1 0 0 1 1 1 1 Capicua transcriptional repressor modulator adh_short_C2 PF13561.6 CRJ80422.1 - 2.3e-52 177.9 0.0 2.9e-52 177.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRJ80422.1 - 1.8e-45 154.8 0.3 2.2e-45 154.5 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CRJ80422.1 - 1.2e-08 35.1 0.3 1.6e-08 34.7 0.3 1.2 1 0 0 1 1 1 1 KR domain PALP PF00291.25 CRJ80422.1 - 0.02 14.3 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Epimerase PF01370.21 CRJ80422.1 - 0.02 14.3 0.1 0.039 13.4 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 CRJ80422.1 - 0.077 12.9 0.2 0.88 9.4 0.0 2.4 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyco_trans_4_4 PF13579.6 CRJ80422.1 - 0.087 13.3 0.1 7.4 7.0 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain THF_DHG_CYH_C PF02882.19 CRJ80422.1 - 0.095 12.0 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain MFS_1 PF07690.16 CRJ80423.1 - 3.4e-34 118.3 37.0 3.4e-34 118.3 37.0 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CRJ80423.1 - 3.2e-13 49.3 7.4 3.2e-13 49.3 7.4 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter DUF4112 PF13430.6 CRJ80423.1 - 0.26 11.6 1.3 1.8 8.9 0.2 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4112) Sugar_tr PF00083.24 CRJ80425.1 - 2.5e-110 369.5 21.5 2.9e-110 369.2 21.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRJ80425.1 - 1e-18 67.4 31.3 4.1e-14 52.3 5.9 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF3084 PF11283.8 CRJ80425.1 - 0.026 14.5 3.6 0.064 13.2 0.2 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF3084) HET PF06985.11 CRJ80432.1 - 3e-09 37.4 0.1 7e-07 29.7 0.0 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Mo-nitro_C PF06967.11 CRJ80432.1 - 0.18 11.8 0.0 0.61 10.1 0.0 1.9 2 0 0 2 2 2 0 Mo-dependent nitrogenase C-terminus Sugar_tr PF00083.24 CRJ80435.1 - 1.6e-27 96.5 32.6 1.8e-13 50.2 7.5 3.2 1 1 2 3 3 3 3 Sugar (and other) transporter Tetraspanin PF00335.20 CRJ80435.1 - 0.0064 16.2 0.0 0.0064 16.2 0.0 2.8 3 0 0 3 3 3 1 Tetraspanin family E1-E2_ATPase PF00122.20 CRJ80436.1 - 1.7e-32 112.4 0.3 1.7e-32 112.4 0.3 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 CRJ80436.1 - 3.1e-20 72.1 0.0 6.1e-20 71.1 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CRJ80436.1 - 7e-16 59.1 1.0 5e-15 56.4 1.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CRJ80436.1 - 1.8e-07 30.8 0.1 7.7e-07 28.7 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CRJ80436.1 - 0.003 17.3 0.3 0.0056 16.5 0.3 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase LptF_LptG PF03739.14 CRJ80436.1 - 0.24 10.2 0.7 0.93 8.3 0.1 1.9 2 0 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG DUF2976 PF11190.8 CRJ80436.1 - 0.26 11.1 3.8 0.54 10.1 1.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) Yip1 PF04893.17 CRJ80436.1 - 5.8 6.6 7.3 5.6 6.6 0.3 2.9 3 0 0 3 3 3 0 Yip1 domain zf-RING_2 PF13639.6 CRJ80437.1 - 6e-12 45.7 7.6 1.3e-11 44.6 7.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 CRJ80437.1 - 1.9e-09 37.1 2.8 3.5e-09 36.2 2.8 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 CRJ80437.1 - 1.4e-08 34.4 6.6 2.4e-08 33.7 6.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CRJ80437.1 - 3.6e-08 33.1 6.4 7.1e-08 32.2 6.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CRJ80437.1 - 1.1e-07 32.0 3.0 1.1e-07 32.0 3.0 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 CRJ80437.1 - 8e-07 28.9 4.2 1.3e-06 28.3 4.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 CRJ80437.1 - 1.9e-06 27.8 0.8 3e-06 27.2 0.8 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 CRJ80437.1 - 5.1e-05 23.2 3.3 0.00014 21.8 3.4 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CRJ80437.1 - 6.9e-05 22.6 4.6 0.00013 21.8 4.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CRJ80437.1 - 0.00018 21.0 6.0 0.00059 19.4 6.0 1.8 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 CRJ80437.1 - 0.00069 19.4 5.9 0.0015 18.4 5.9 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C2H2_3 PF13878.6 CRJ80437.1 - 0.0086 15.9 0.9 0.024 14.4 0.0 2.1 2 0 0 2 2 2 1 zinc-finger of acetyl-transferase ESCO zf-C3HC4_4 PF15227.6 CRJ80437.1 - 0.017 15.3 4.2 0.048 13.8 4.2 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING PepSY_TM PF03929.16 CRJ80437.1 - 0.03 14.0 0.0 0.034 13.8 0.0 1.2 1 0 0 1 1 1 0 PepSY-associated TM region RINGv PF12906.7 CRJ80437.1 - 0.036 14.2 6.1 0.036 14.2 6.1 1.7 2 0 0 2 2 1 0 RING-variant domain zf-RING_6 PF14835.6 CRJ80437.1 - 0.063 13.1 1.0 0.12 12.2 1.0 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 CRJ80437.1 - 0.086 12.7 3.2 0.23 11.3 3.1 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3H2C3 PF17122.5 CRJ80437.1 - 0.097 12.7 5.4 0.23 11.5 5.4 1.7 1 1 0 1 1 1 0 Zinc-finger DUF983 PF06170.12 CRJ80437.1 - 0.099 13.1 1.1 2 8.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF983) zinc_ribbon_16 PF17034.5 CRJ80437.1 - 0.18 12.1 3.2 0.39 10.9 3.2 1.5 1 1 0 1 1 1 0 Zinc-ribbon like family zf-Nse PF11789.8 CRJ80437.1 - 0.24 11.3 2.0 0.37 10.6 2.0 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING-like PF08746.11 CRJ80437.1 - 1.1 9.7 4.4 1.9 8.9 4.4 1.4 1 0 0 1 1 1 0 RING-like domain PHD PF00628.29 CRJ80437.1 - 3.1 7.7 8.1 1.4 8.9 5.6 1.7 2 0 0 2 2 1 0 PHD-finger DIOX_N PF14226.6 CRJ80440.1 - 6e-05 23.8 0.0 0.00012 22.8 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 CRJ80440.1 - 0.00014 22.3 0.0 0.00025 21.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DEAD PF00270.29 CRJ80444.1 - 3.6e-33 114.8 0.0 6.9e-17 61.8 0.0 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 CRJ80444.1 - 1.8e-20 73.4 0.0 4.2e-20 72.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CRJ80444.1 - 1.8e-07 31.4 1.7 1.9e-07 31.2 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Cwf_Cwc_15 PF04889.12 CRJ80444.1 - 0.0075 16.0 25.8 0.037 13.8 7.6 2.4 2 0 0 2 2 2 2 Cwf15/Cwc15 cell cycle control protein UvrD-helicase PF00580.21 CRJ80444.1 - 0.01 15.4 2.3 0.016 14.7 0.0 2.1 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain BUD22 PF09073.10 CRJ80444.1 - 0.028 13.8 29.2 0.029 13.7 7.0 2.2 2 0 0 2 2 2 0 BUD22 SAPS PF04499.15 CRJ80444.1 - 0.46 9.2 13.0 0.69 8.6 0.2 2.3 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein RR_TM4-6 PF06459.12 CRJ80444.1 - 1.1 9.0 18.1 10 5.8 13.6 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Tim54 PF11711.8 CRJ80444.1 - 1.9 7.2 16.5 2 7.1 0.2 2.2 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 AF-4 PF05110.13 CRJ80444.1 - 2.6 6.0 33.9 1.9 6.5 12.8 2.1 2 0 0 2 2 2 0 AF-4 proto-oncoprotein CDC27 PF09507.10 CRJ80444.1 - 5.5 6.3 32.8 6.2 6.1 1.7 2.2 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 CMS1 PF14617.6 CRJ80444.1 - 9 5.5 12.8 20 4.4 0.0 2.7 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit PIGA PF08288.12 CRJ80447.1 - 4.8e-46 155.3 1.1 9.7e-46 154.3 1.1 1.5 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 CRJ80447.1 - 1.2e-27 97.0 0.5 1.9e-27 96.3 0.5 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 CRJ80447.1 - 9.1e-12 45.7 0.0 1.6e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 CRJ80447.1 - 0.0014 18.6 0.1 0.0022 18.0 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_transf_5 PF08323.11 CRJ80447.1 - 0.13 11.9 0.0 0.4 10.3 0.0 1.8 2 0 0 2 2 2 0 Starch synthase catalytic domain SKA1 PF07160.12 CRJ80449.1 - 0.00014 21.8 1.2 0.00017 21.5 1.2 1.1 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 1 Spc29 PF17082.5 CRJ80449.1 - 0.00041 20.3 1.0 0.00053 19.9 1.0 1.2 1 0 0 1 1 1 1 Spindle Pole Component 29 FliD_N PF02465.18 CRJ80449.1 - 0.0006 20.5 2.3 0.00088 19.9 2.3 1.3 1 0 0 1 1 1 1 Flagellar hook-associated protein 2 N-terminus SlyX PF04102.12 CRJ80449.1 - 0.0022 18.6 2.6 0.0022 18.6 2.6 1.7 2 0 0 2 2 2 1 SlyX Filament PF00038.21 CRJ80449.1 - 0.0069 16.0 2.0 0.0083 15.7 2.0 1.1 1 0 0 1 1 1 1 Intermediate filament protein DUF4686 PF15742.5 CRJ80449.1 - 0.0085 15.3 1.3 0.011 15.0 1.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4686) XhlA PF10779.9 CRJ80449.1 - 0.0094 16.1 2.4 0.015 15.5 2.4 1.2 1 0 0 1 1 1 1 Haemolysin XhlA DUF16 PF01519.16 CRJ80449.1 - 0.019 15.4 1.0 0.027 14.9 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF16 Allexi_40kDa PF05549.11 CRJ80449.1 - 0.02 14.4 2.0 0.026 14.1 2.0 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein Fib_alpha PF08702.10 CRJ80449.1 - 0.046 13.9 0.8 0.08 13.1 0.8 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family TipE PF16972.5 CRJ80449.1 - 0.048 12.8 0.8 0.063 12.5 0.8 1.1 1 0 0 1 1 1 0 Na+ channel auxiliary subunit TipE CytochromB561_N PF09786.9 CRJ80449.1 - 0.14 11.1 6.1 0.17 10.9 6.1 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal BLOC1_2 PF10046.9 CRJ80449.1 - 0.18 12.1 1.9 0.42 10.9 1.9 1.6 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Macoilin PF09726.9 CRJ80449.1 - 0.37 9.3 4.2 0.41 9.2 4.2 1.0 1 0 0 1 1 1 0 Macoilin family DUF4407 PF14362.6 CRJ80449.1 - 0.76 9.1 3.7 0.84 8.9 3.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CSN5_C PF18323.1 CRJ80449.1 - 3.8 8.5 6.9 74 4.4 6.9 2.2 1 1 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain GREB1 PF15782.5 CRJ80449.1 - 4.3 4.3 7.0 4.4 4.3 7.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer pRN1_helical PF13010.6 CRJ80450.1 - 0.23 11.4 0.0 0.37 10.8 0.0 1.3 1 0 0 1 1 1 0 Primase helical domain Asp PF00026.23 CRJ80452.1 - 6.7e-17 61.9 0.0 9.6e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease DUF1811 PF08838.10 CRJ80452.1 - 0.1 12.9 0.1 0.83 9.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1811) HSP70 PF00012.20 CRJ80455.1 - 6.6e-57 193.0 20.6 7.7e-57 192.8 10.8 2.8 2 1 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 CRJ80455.1 - 0.0034 16.3 0.1 0.014 14.2 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein S_100 PF01023.19 CRJ80455.1 - 0.021 14.5 0.1 0.12 12.1 0.0 2.3 2 0 0 2 2 2 0 S-100/ICaBP type calcium binding domain NPV_P10 PF05531.12 CRJ80455.1 - 0.11 13.0 0.3 0.81 10.2 0.3 2.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein TMEM247 PF15444.6 CRJ80455.1 - 5.7 6.9 8.2 11 6.0 0.8 2.6 2 0 0 2 2 2 0 Transmembrane protein 247 Mucin PF01456.17 CRJ80455.1 - 6.6 6.7 16.3 2.3 8.2 4.6 3.3 3 0 0 3 3 3 0 Mucin-like glycoprotein DUF4711 PF15829.5 CRJ80455.1 - 8.1 6.3 8.1 1.1 9.1 2.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4711) Fungal_trans PF04082.18 CRJ80457.1 - 4.8e-17 61.9 0.1 8.3e-17 61.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRJ80457.1 - 2.2e-07 30.9 15.3 4.1e-07 30.0 15.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Thiolase_N PF00108.23 CRJ80460.1 - 6.4e-16 58.5 0.5 3.7e-15 56.0 0.5 2.1 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CRJ80460.1 - 2e-10 40.4 2.8 3.3e-10 39.7 0.7 2.5 2 1 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 CRJ80460.1 - 8e-08 32.0 0.4 1e-05 25.3 0.1 2.6 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 CRJ80460.1 - 0.0005 19.7 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.11 CRJ80460.1 - 0.052 12.3 0.2 0.09 11.5 0.2 1.3 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) Meckelin PF09773.9 CRJ80463.1 - 3.4e-05 22.2 3.1 3.4e-05 22.2 3.1 1.4 2 0 0 2 2 2 1 Meckelin (Transmembrane protein 67) DUF2070 PF09843.9 CRJ80463.1 - 1.1 7.5 12.7 1.6 6.9 12.7 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF5423 PF17461.2 CRJ80463.1 - 1.9 7.3 5.1 3.3 6.5 5.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5423) MFS_1 PF07690.16 CRJ80463.1 - 8.5 5.2 30.7 5.2 5.9 15.2 2.4 2 1 1 3 3 3 0 Major Facilitator Superfamily adh_short_C2 PF13561.6 CRJ80464.1 - 3.6e-45 154.3 0.6 4.2e-45 154.1 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRJ80464.1 - 8e-41 139.6 0.1 1e-40 139.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CRJ80464.1 - 6.5e-09 35.9 1.0 1.1e-08 35.3 1.0 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 CRJ80464.1 - 0.0042 16.5 0.0 0.0072 15.8 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CRJ80464.1 - 0.008 15.7 0.1 0.015 14.7 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 CRJ80464.1 - 0.019 14.9 0.2 0.049 13.5 0.2 1.7 1 1 0 1 1 1 0 NAD(P)H-binding AdoHcyase_NAD PF00670.21 CRJ80464.1 - 0.021 14.9 0.0 0.041 14.0 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain BTB_2 PF02214.22 CRJ80465.1 - 0.00019 21.7 0.1 0.00067 20.0 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain DUF489 PF04356.12 CRJ80467.1 - 0.11 12.5 5.2 0.48 10.4 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF489) Neur_chan_memb PF02932.16 CRJ80467.1 - 0.67 10.0 3.8 1.1 9.2 3.8 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Laminin_II PF06009.12 CRJ80467.1 - 1.4 9.0 8.3 0.24 11.4 2.0 2.3 2 0 0 2 2 2 0 Laminin Domain II COG2 PF06148.11 CRJ80467.1 - 4.5 7.4 9.3 0.25 11.4 1.2 2.4 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 HATPase_c_3 PF13589.6 CRJ80470.1 - 0.0012 18.7 0.0 0.0026 17.6 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3883 PF13020.6 CRJ80470.1 - 0.0016 18.5 0.0 0.0034 17.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) Cyt-b5 PF00173.28 CRJ80471.1 - 3.8e-11 43.0 0.1 5.6e-11 42.4 0.1 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Cupredoxin_1 PF13473.6 CRJ80472.1 - 0.00034 20.7 0.0 0.0014 18.7 0.0 1.8 1 1 1 2 2 2 1 Cupredoxin-like domain CENP-X PF09415.10 CRJ80475.1 - 1.1e-18 67.3 0.1 1.1e-18 67.3 0.1 2.0 2 0 0 2 2 2 1 CENP-S associating Centromere protein X Mito_carr PF00153.27 CRJ80479.1 - 3e-65 216.2 4.1 9.5e-24 83.1 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_S25 PF03297.15 CRJ80479.1 - 1.3e-30 105.6 2.6 2.1e-30 104.9 2.6 1.4 1 0 0 1 1 1 1 S25 ribosomal protein MarR_2 PF12802.7 CRJ80479.1 - 0.0058 16.5 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 MarR family DUF4748 PF15932.5 CRJ80479.1 - 0.044 13.5 0.8 0.14 11.9 0.8 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) HTH_24 PF13412.6 CRJ80479.1 - 0.046 13.3 0.1 0.084 12.4 0.1 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MarR PF01047.22 CRJ80479.1 - 0.17 11.8 0.0 0.39 10.7 0.0 1.5 1 0 0 1 1 1 0 MarR family Ribosomal_S7 PF00177.21 CRJ80482.1 - 4.2e-37 127.1 1.6 5.4e-37 126.7 1.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Acetyltransf_1 PF00583.25 CRJ80484.1 - 3.3e-05 24.1 0.0 0.00015 22.0 0.0 2.1 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CRJ80484.1 - 6.5e-05 22.9 0.0 0.03 14.2 0.0 2.3 1 1 1 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.6 CRJ80484.1 - 0.00023 21.8 0.0 1.8 9.4 0.0 3.0 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CRJ80484.1 - 0.0067 16.8 0.0 0.016 15.6 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CRJ80484.1 - 0.012 15.7 0.0 0.021 15.0 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase RE_MamI PF09567.10 CRJ80484.1 - 0.15 11.6 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 MamI restriction endonuclease LSM14 PF12701.7 CRJ80487.1 - 2.3e-31 107.7 0.1 3.7e-31 107.0 0.1 1.3 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 CRJ80487.1 - 9.1e-22 77.9 1.5 9.1e-22 77.9 1.5 2.3 2 0 0 2 2 2 1 FDF domain SM-ATX PF14438.6 CRJ80487.1 - 3.9e-07 30.1 0.0 8e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Ataxin 2 SM domain Spt20 PF12090.8 CRJ80487.1 - 5.3 6.6 13.8 8.9 5.8 13.8 1.3 1 0 0 1 1 1 0 Spt20 family Tcf25 PF04910.14 CRJ80490.1 - 1.1e-56 192.4 0.0 1.9e-56 191.7 0.0 1.4 1 1 0 1 1 1 1 Transcriptional repressor TCF25 EcsC PF12787.7 CRJ80490.1 - 0.012 15.2 5.0 0.014 15.0 0.0 2.3 2 0 0 2 2 2 0 EcsC protein family Acetyltransf_1 PF00583.25 CRJ80490.1 - 0.071 13.3 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Apt1 PF10351.9 CRJ80490.1 - 3 6.6 7.6 4.5 6.0 7.6 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain RNA_polI_A34 PF08208.11 CRJ80490.1 - 5.7 7.0 29.2 0.32 11.0 23.8 1.6 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 Wbp11 PF09429.10 CRJ80490.1 - 8.2 6.9 20.8 0.24 11.8 9.8 2.8 2 1 1 3 3 3 0 WW domain binding protein 11 BSP_II PF05432.11 CRJ80490.1 - 9.9 5.8 25.5 0.41 10.3 16.6 2.3 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) HMA PF00403.26 CRJ80492.1 - 4.8e-16 59.0 0.2 7.2e-16 58.4 0.2 1.3 1 0 0 1 1 1 1 Heavy-metal-associated domain HydF_tetramer PF18133.1 CRJ80492.1 - 0.035 13.9 0.0 0.043 13.6 0.0 1.2 1 0 0 1 1 1 0 Hydrogen maturase F tetramerization domain Herpes_UL49_5 PF05702.11 CRJ80501.1 - 0.038 14.1 0.4 0.075 13.1 0.2 1.5 1 1 0 1 1 1 0 Herpesvirus UL49.5 envelope/tegument protein Pyr_redox_2 PF07992.14 CRJ80504.1 - 4.5e-38 131.1 0.1 7.5e-38 130.4 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CRJ80504.1 - 6.3e-33 113.3 0.4 1.5e-32 112.2 0.2 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 CRJ80504.1 - 3.2e-18 66.0 0.0 8.2e-18 64.8 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DEAD PF00270.29 CRJ80504.1 - 6.4e-17 61.9 0.0 1.6e-16 60.5 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CRJ80504.1 - 1.3e-16 60.9 0.0 6.4e-15 55.5 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Pyr_redox_3 PF13738.6 CRJ80504.1 - 8.1e-06 25.3 0.0 1.3e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase MOSP_N PF02707.16 CRJ80504.1 - 0.13 12.0 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Major Outer Sheath Protein N-terminal region LRR_4 PF12799.7 CRJ80507.1 - 5.5e-17 61.6 12.2 9.8e-07 29.0 1.7 3.3 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CRJ80507.1 - 2.5e-13 49.6 3.7 7.2e-09 35.3 0.1 2.6 2 1 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.33 CRJ80507.1 - 0.00011 22.3 2.8 3.3 8.6 0.1 4.3 3 1 1 4 4 4 2 Leucine Rich Repeat LRR_6 PF13516.6 CRJ80507.1 - 0.00053 19.8 2.0 0.46 10.7 0.1 3.6 4 0 0 4 4 4 2 Leucine Rich repeat Helicase_C PF00271.31 CRJ80510.1 - 2.2e-16 60.2 0.0 3.3e-15 56.4 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CRJ80510.1 - 0.002 17.9 0.0 0.0064 16.3 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase ClpB_D2-small PF10431.9 CRJ80510.1 - 0.14 12.2 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 C-terminal, D2-small domain, of ClpB protein DEAD PF00270.29 CRJ80512.1 - 2.2e-08 34.1 0.0 3e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase SOG2 PF10428.9 CRJ80514.1 - 1.6e-54 186.0 4.4 2e-29 103.2 0.0 3.0 2 1 1 3 3 3 2 RAM signalling pathway protein LRR_4 PF12799.7 CRJ80514.1 - 1.6e-16 60.1 1.1 3.4e-06 27.3 0.0 3.9 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CRJ80514.1 - 7.9e-15 54.4 4.8 2.3e-08 33.7 0.1 3.2 3 0 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.33 CRJ80514.1 - 0.0006 20.0 3.2 8.9 7.3 0.1 5.2 5 0 0 5 5 5 2 Leucine Rich Repeat DUF2408 PF10303.9 CRJ80514.1 - 0.032 14.8 0.0 0.25 11.9 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2408) LRR_6 PF13516.6 CRJ80514.1 - 0.24 11.6 10.9 1.2 9.4 0.1 4.7 6 0 0 6 6 6 0 Leucine Rich repeat Steroid_dh PF02544.16 CRJ80522.1 - 1.2e-31 109.7 0.3 2.2e-31 108.9 0.3 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 CRJ80522.1 - 0.0014 18.2 2.3 0.0025 17.4 0.4 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF1295) An_peroxidase PF03098.15 CRJ80525.1 - 3.4e-28 98.5 0.0 1.8e-18 66.4 0.0 3.3 1 1 1 2 2 2 2 Animal haem peroxidase Steroid_dh PF02544.16 CRJ80525.1 - 1e-27 96.9 0.2 2e-27 96.0 0.2 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 CRJ80525.1 - 0.012 15.1 0.8 0.028 13.9 0.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1295) Ribosomal_S8e PF01201.22 CRJ80530.1 - 4.5e-08 33.3 0.0 1.3e-07 31.8 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein S8e Ribosomal_S8e PF01201.22 CRJ80535.1 - 5.3e-57 191.8 1.4 6.3e-57 191.6 1.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e RabGAP-TBC PF00566.18 CRJ80538.1 - 1.7e-52 178.2 0.2 1.5e-48 165.3 0.3 3.5 2 1 0 2 2 2 2 Rab-GTPase-TBC domain CENP-C_C PF11699.8 CRJ80538.1 - 7.1e-33 112.7 0.3 1.3e-32 111.9 0.3 1.4 1 0 0 1 1 1 1 Mif2/CENP-C like Mif2_N PF15624.6 CRJ80538.1 - 1.4e-28 100.3 2.0 1.4e-28 100.3 2.0 8.8 7 3 0 8 8 3 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Cupin_2 PF07883.11 CRJ80538.1 - 1.2e-06 28.2 0.0 2.9e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Cupin domain Cnn_1N PF07989.11 CRJ80538.1 - 0.0061 16.7 19.7 0.051 13.7 5.2 3.3 1 1 1 2 2 2 2 Centrosomin N-terminal motif 1 KASH_CCD PF14662.6 CRJ80538.1 - 0.23 11.3 23.6 0.44 10.4 22.7 2.0 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH V_ATPase_I PF01496.19 CRJ80538.1 - 0.44 8.4 8.6 1.3 6.9 8.6 1.8 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4094 PF13334.6 CRJ80538.1 - 0.44 11.0 8.0 0.47 10.9 5.1 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) HALZ PF02183.18 CRJ80538.1 - 1.2 9.4 11.0 3.3 8.0 3.0 3.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper bZIP_1 PF00170.21 CRJ80538.1 - 5.9 7.1 17.8 4.1 7.6 1.1 3.4 2 1 1 3 3 3 0 bZIP transcription factor FlaC_arch PF05377.11 CRJ80538.1 - 7 7.1 8.9 61 4.1 0.6 3.7 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) RNase_HII PF01351.18 CRJ80542.1 - 2e-48 164.9 0.0 9.2e-48 162.7 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease HII RHD3 PF05879.12 CRJ80547.1 - 0 1042.8 0.0 0 1042.6 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 CRJ80547.1 - 1.1e-09 38.0 0.2 1.8e-09 37.3 0.2 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.23 CRJ80547.1 - 2.9e-06 27.4 0.0 6.6e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 CRJ80547.1 - 3.9e-05 23.7 0.0 9.5e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 CRJ80547.1 - 0.002 18.4 0.0 0.0089 16.3 0.0 2.1 1 0 0 1 1 1 1 AAA domain DSBA PF01323.20 CRJ80547.1 - 0.003 17.4 0.5 0.0059 16.4 0.1 1.7 2 0 0 2 2 2 1 DSBA-like thioredoxin domain AAA_16 PF13191.6 CRJ80547.1 - 0.013 15.9 0.1 0.1 13.0 0.0 2.4 3 0 0 3 3 3 0 AAA ATPase domain Septin PF00735.18 CRJ80547.1 - 0.05 12.9 0.1 0.086 12.1 0.1 1.3 1 0 0 1 1 1 0 Septin ATP-grasp_2 PF08442.10 CRJ80550.1 - 1.1e-34 119.8 0.9 1.1e-34 119.8 0.9 1.8 1 1 1 2 2 2 1 ATP-grasp domain ATP-grasp_5 PF13549.6 CRJ80550.1 - 2.4e-06 27.2 0.2 5.7e-06 26.0 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 CRJ80550.1 - 0.00011 22.0 0.1 0.00021 21.1 0.1 1.5 1 0 0 1 1 1 1 CoA-ligase GARS_A PF01071.19 CRJ80550.1 - 0.00024 20.9 2.2 0.0098 15.7 0.1 2.5 1 1 2 3 3 3 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Fructosamin_kin PF03881.14 CRJ80556.1 - 9.3e-70 235.1 0.0 1.1e-69 234.9 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 CRJ80556.1 - 8.1e-07 29.2 0.0 1.2e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 CRJ80556.1 - 0.22 10.3 0.0 0.35 9.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) ADH_zinc_N PF00107.26 CRJ80558.1 - 2.1e-22 79.5 0.1 3.5e-22 78.8 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CRJ80558.1 - 1.2e-15 57.3 0.2 2.2e-07 30.7 0.0 2.4 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 CRJ80558.1 - 0.0033 18.5 0.0 0.0052 17.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 CRJ80558.1 - 0.15 11.4 0.1 0.25 10.7 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.21 CRJ80558.1 - 0.18 11.1 1.0 0.32 10.3 1.0 1.3 1 0 0 1 1 1 0 ThiF family Actin PF00022.19 CRJ80565.1 - 1.4e-85 287.4 0.0 4.1e-83 279.3 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 CRJ80565.1 - 0.15 10.9 0.0 4.8 5.9 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein Asparaginase_2 PF01112.18 CRJ80568.1 - 2.3e-41 141.8 4.1 6.5e-28 97.6 0.1 2.2 2 0 0 2 2 2 2 Asparaginase Actin PF00022.19 CRJ80571.1 - 1.2e-25 90.0 0.0 1.4e-25 89.7 0.0 1.1 1 0 0 1 1 1 1 Actin Tfb4 PF03850.14 CRJ80571.1 - 1.7e-20 73.7 8.9 2.2e-20 73.3 8.9 1.1 1 0 0 1 1 1 1 Transcription factor Tfb4 Asparaginase_2 PF01112.18 CRJ80575.1 - 1e-24 87.1 0.0 6.4e-24 84.5 0.1 2.2 2 1 0 2 2 2 1 Asparaginase Tfb4 PF03850.14 CRJ80577.1 - 8.5e-47 159.9 0.5 1e-46 159.6 0.5 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 UNC45-central PF11701.8 CRJ80580.1 - 5.8e-51 172.5 0.5 3.8e-47 160.1 0.0 3.7 3 0 0 3 3 3 2 Myosin-binding striated muscle assembly central HEAT_2 PF13646.6 CRJ80580.1 - 0.0026 18.1 17.5 0.026 14.9 2.5 5.6 4 2 1 5 5 5 2 HEAT repeats Vac14_Fab1_bd PF12755.7 CRJ80580.1 - 0.031 14.9 0.0 0.12 13.0 0.0 2.1 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region HEAT PF02985.22 CRJ80580.1 - 0.12 12.6 11.1 3 8.4 0.0 5.9 6 0 0 6 6 6 0 HEAT repeat HEAT_EZ PF13513.6 CRJ80580.1 - 0.29 11.7 8.4 9.6 6.8 0.1 5.2 5 0 0 5 5 5 0 HEAT-like repeat tRNA_U5-meth_tr PF05958.11 CRJ80582.1 - 2.6e-11 43.1 0.0 3.3e-10 39.5 0.0 2.4 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_15 PF09445.10 CRJ80582.1 - 2.6e-05 23.9 0.0 4.3e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_31 PF13847.6 CRJ80582.1 - 0.0062 16.4 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRJ80582.1 - 0.0097 16.6 0.0 0.021 15.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 CRJ80582.1 - 0.026 13.9 0.0 0.05 13.0 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltrans_SAM PF10672.9 CRJ80582.1 - 0.065 12.4 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 S-adenosylmethionine-dependent methyltransferase G_glu_transpept PF01019.21 CRJ80584.1 - 3.5e-169 563.9 0.3 4e-169 563.6 0.3 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase DUF4981 PF16353.5 CRJ80584.1 - 0.058 13.9 0.2 0.13 12.7 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function(DUF4981) ALG11_N PF15924.5 CRJ80588.1 - 4e-79 265.5 0.4 2.6e-78 262.9 0.0 2.1 2 0 0 2 2 2 1 ALG11 mannosyltransferase N-terminus Syntaxin_2 PF14523.6 CRJ80588.1 - 4.5e-24 84.7 3.3 4.5e-24 84.7 3.3 2.1 2 0 0 2 2 2 1 Syntaxin-like protein Glycos_transf_1 PF00534.20 CRJ80588.1 - 2.4e-20 72.8 0.0 4.8e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CRJ80588.1 - 1.4e-09 38.4 0.0 3.6e-09 37.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 SNARE PF05739.19 CRJ80588.1 - 2.5e-07 30.6 0.3 6.9e-07 29.2 0.3 1.8 1 0 0 1 1 1 1 SNARE domain Glyco_transf_4 PF13439.6 CRJ80588.1 - 0.0018 18.3 0.0 0.0034 17.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Syntaxin PF00804.25 CRJ80588.1 - 0.0031 17.2 8.8 0.0064 16.2 8.8 1.5 1 0 0 1 1 1 1 Syntaxin FapA PF03961.13 CRJ80588.1 - 0.037 12.6 0.8 0.078 11.6 0.8 1.5 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF883 PF05957.13 CRJ80588.1 - 0.96 10.1 10.7 0.54 10.9 0.1 3.8 3 1 2 5 5 5 0 Bacterial protein of unknown function (DUF883) 60KD_IMP PF02096.20 CRJ80590.1 - 0.00017 21.6 0.0 0.00022 21.2 0.0 1.4 1 1 0 1 1 1 1 60Kd inner membrane protein Ndc1_Nup PF09531.10 CRJ80593.1 - 6e-176 586.7 6.4 1.4e-135 453.4 0.0 2.0 2 0 0 2 2 2 2 Nucleoporin protein Ndc1-Nup DUF3938 PF13074.6 CRJ80593.1 - 0.025 14.8 1.0 0.069 13.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3938) Pkinase PF00069.25 CRJ80596.1 - 1.3e-34 119.7 0.0 1.3e-16 60.8 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CRJ80596.1 - 3.7e-11 42.8 0.0 0.00045 19.6 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase Autoind_bind PF03472.15 CRJ80596.1 - 0.17 11.4 0.0 0.33 10.4 0.0 1.4 1 0 0 1 1 1 0 Autoinducer binding domain DUF1524 PF07510.11 CRJ80598.1 - 3.2e-07 30.3 0.0 3.8e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) HNH_4 PF13395.6 CRJ80598.1 - 0.051 13.5 0.4 0.76 9.7 0.4 2.3 1 1 0 1 1 1 0 HNH endonuclease HSF_DNA-bind PF00447.17 CRJ80603.1 - 1.8e-31 108.6 0.1 9.2e-25 87.1 0.1 2.4 2 0 0 2 2 2 2 HSF-type DNA-binding Ets PF00178.22 CRJ80603.1 - 0.12 12.9 0.0 30 5.2 0.0 2.4 2 0 0 2 2 2 0 Ets-domain Ank_4 PF13637.6 CRJ80607.1 - 1e-08 35.5 0.0 3.4e-08 33.9 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CRJ80607.1 - 1.5e-05 25.5 0.0 6.3e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) NACHT PF05729.12 CRJ80607.1 - 8.9e-05 22.5 0.1 0.051 13.5 0.0 2.7 1 1 1 2 2 2 2 NACHT domain SesA PF17107.5 CRJ80607.1 - 0.00019 21.6 0.2 0.0004 20.6 0.2 1.5 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Ank_5 PF13857.6 CRJ80607.1 - 0.00033 20.9 0.1 0.002 18.4 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 CRJ80607.1 - 0.0004 20.7 0.0 0.4 11.2 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 CRJ80607.1 - 0.0027 18.1 0.0 2.4 9.0 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat Mg_chelatase PF01078.21 CRJ80607.1 - 0.14 11.5 0.1 0.28 10.6 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CRJ80607.1 - 0.16 12.0 0.7 1.1 9.2 0.7 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Ank_2 PF12796.7 CRJ80610.1 - 2.2e-11 44.2 0.1 2.4e-05 24.8 0.0 2.0 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CRJ80610.1 - 3.5e-09 37.0 0.0 1.2e-08 35.3 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 CRJ80610.1 - 1.2e-05 25.5 0.0 0.2 12.2 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat SesA PF17107.5 CRJ80610.1 - 1.6e-05 25.0 0.1 3.8e-05 23.9 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Ank_5 PF13857.6 CRJ80610.1 - 2e-05 24.8 0.2 0.00012 22.3 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 CRJ80610.1 - 0.00058 20.1 0.0 2.8 8.8 0.0 3.5 2 1 0 2 2 2 2 Ankyrin repeat Arena_ncap_C PF17290.2 CRJ80610.1 - 0.14 11.5 0.1 0.25 10.6 0.1 1.3 1 0 0 1 1 1 0 Arenavirus nucleocapsid C-terminal domain Mcl1_mid PF12341.8 CRJ80613.1 - 3.3e-124 414.1 0.0 2.3e-95 319.4 0.0 3.3 3 0 0 3 3 3 3 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 CRJ80613.1 - 4.7e-20 71.5 1.5 1.1e-07 32.4 0.0 6.9 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRJ80613.1 - 2.6e-18 66.1 0.0 1.9e-06 28.1 0.0 6.6 2 1 4 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 CRJ80613.1 - 0.00032 19.9 0.0 0.00084 18.5 0.0 1.5 1 1 0 1 1 1 1 Coatomer WD associated region Ge1_WD40 PF16529.5 CRJ80613.1 - 0.0022 17.0 0.0 0.99 8.3 0.0 2.6 2 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 CRJ80613.1 - 0.0065 16.4 0.0 0.052 13.4 0.0 2.4 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 CRJ80613.1 - 0.016 14.6 0.0 3.5 6.8 0.0 2.4 2 1 0 2 2 2 0 WD40-like domain DNA_pol_alpha_N PF12254.8 CRJ80613.1 - 0.068 13.3 2.9 0.26 11.4 2.9 2.0 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal MMS1_N PF10433.9 CRJ80613.1 - 0.12 10.9 0.0 0.55 8.8 0.0 2.0 2 1 0 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term IKI3 PF04762.12 CRJ80613.1 - 0.15 10.0 0.0 0.28 9.1 0.0 1.3 1 0 0 1 1 1 0 IKI3 family KTSC PF13619.6 CRJ80613.1 - 0.17 11.8 0.0 9.6 6.1 0.0 2.6 2 0 0 2 2 2 0 KTSC domain WD40 PF00400.32 CRJ80616.1 - 3.9e-15 56.0 11.0 0.086 13.7 0.0 7.8 8 0 0 8 8 8 5 WD domain, G-beta repeat DUF3494 PF11999.8 CRJ80616.1 - 0.0017 18.0 0.1 0.93 9.1 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3494) PALB2_WD40 PF16756.5 CRJ80616.1 - 0.0032 16.4 0.1 2.3 7.1 0.0 2.6 3 0 0 3 3 3 2 Partner and localizer of BRCA2 WD40 domain Nup160 PF11715.8 CRJ80616.1 - 0.0036 16.0 0.8 0.67 8.5 0.1 3.3 3 1 0 3 3 3 1 Nucleoporin Nup120/160 PQQ_3 PF13570.6 CRJ80616.1 - 0.036 14.6 0.0 0.036 14.6 0.0 4.9 6 1 0 6 6 6 0 PQQ-like domain DNA_pol_delta_4 PF04081.13 CRJ80618.1 - 3.3e-42 143.9 4.5 3.6e-42 143.8 3.3 1.6 2 0 0 2 2 2 1 DNA polymerase delta, subunit 4 WD40 PF00400.32 CRJ80618.1 - 2.3e-30 104.2 43.5 7.5e-07 29.8 1.3 12.2 14 0 0 14 14 14 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRJ80618.1 - 4.3e-19 68.6 11.1 0.058 13.7 0.4 8.3 2 2 5 8 8 8 7 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CRJ80618.1 - 0.0011 17.8 1.9 0.7 8.5 0.1 2.3 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Nbas_N PF15492.6 CRJ80618.1 - 0.0018 17.7 0.1 9.3 5.5 0.0 4.2 2 2 2 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.11 CRJ80618.1 - 0.043 12.5 0.0 6.5 5.4 0.0 2.3 2 0 0 2 2 2 0 Nup133 N terminal like Q_salvage PF10343.9 CRJ80623.1 - 8.3e-46 156.8 0.0 1.2e-45 156.3 0.0 1.2 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family ThiF PF00899.21 CRJ80625.1 - 1.3e-63 214.7 0.0 1.5e-63 214.4 0.0 1.2 1 0 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 CRJ80625.1 - 3e-13 50.2 0.1 6.8e-13 49.0 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain NAD_binding_7 PF13241.6 CRJ80625.1 - 2.3e-05 24.7 0.0 6.7e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 CRJ80625.1 - 0.003 17.6 0.0 0.0058 16.7 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 CRJ80625.1 - 0.0042 17.3 0.9 0.026 14.8 0.1 2.4 2 1 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Pyr_redox PF00070.27 CRJ80625.1 - 0.024 15.2 0.2 1.6 9.3 0.1 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase ROKNT PF08067.11 CRJ80625.1 - 0.045 14.0 0.3 0.15 12.4 0.3 1.9 1 0 0 1 1 1 0 ROKNT (NUC014) domain E2_bind PF08825.10 CRJ80625.1 - 0.079 13.1 0.1 0.22 11.7 0.1 1.8 1 1 0 1 1 1 0 E2 binding domain DASH_Dam1 PF08653.10 CRJ80625.1 - 0.088 12.6 0.3 2.5 7.9 0.1 2.4 2 0 0 2 2 2 0 DASH complex subunit Dam1 adh_short_C2 PF13561.6 CRJ80628.1 - 5e-47 160.4 1.1 2.3e-40 138.6 0.2 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRJ80628.1 - 1.6e-42 145.2 0.1 2.9e-32 111.7 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase Epimerase PF01370.21 CRJ80628.1 - 9.2e-06 25.3 0.0 4.3e-05 23.1 0.0 2.1 3 1 0 3 3 3 1 NAD dependent epimerase/dehydratase family KR PF08659.10 CRJ80628.1 - 1e-05 25.6 2.9 7.2e-05 22.8 2.9 2.1 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 CRJ80628.1 - 0.00086 19.2 0.0 0.0021 17.9 0.0 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DFP PF04127.15 CRJ80628.1 - 0.0037 17.1 1.6 0.27 11.1 0.1 2.7 2 1 0 2 2 2 1 DNA / pantothenate metabolism flavoprotein THF_DHG_CYH_C PF02882.19 CRJ80628.1 - 0.024 14.0 0.0 0.24 10.7 0.0 2.1 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain RmlD_sub_bind PF04321.17 CRJ80628.1 - 0.03 13.4 0.4 0.15 11.1 0.1 2.0 1 1 1 2 2 2 0 RmlD substrate binding domain ApbA PF02558.16 CRJ80628.1 - 0.035 13.8 0.0 0.07 12.8 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Polysacc_synt_2 PF02719.15 CRJ80628.1 - 0.052 12.7 0.0 0.1 11.7 0.0 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein DUF1776 PF08643.10 CRJ80628.1 - 0.071 12.5 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) F420_oxidored PF03807.17 CRJ80628.1 - 0.093 13.3 0.1 0.24 12.0 0.1 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Esterase_phd PF10503.9 CRJ80631.1 - 2.4e-24 86.1 1.1 4.2e-24 85.3 1.1 1.4 1 0 0 1 1 1 1 Esterase PHB depolymerase PAP2 PF01569.21 CRJ80631.1 - 4.5e-18 65.3 1.2 4.5e-18 65.3 1.2 2.0 2 0 0 2 2 2 1 PAP2 superfamily Peptidase_S9 PF00326.21 CRJ80631.1 - 1.6e-06 27.7 0.2 3.1e-06 26.8 0.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family PAP2_3 PF14378.6 CRJ80631.1 - 0.00094 18.9 3.4 0.00094 18.9 3.4 2.0 2 0 0 2 2 2 1 PAP2 superfamily Peptidase_U4 PF03419.13 CRJ80631.1 - 0.96 8.7 4.6 2.7 7.2 1.2 2.3 1 1 1 2 2 2 0 Sporulation factor SpoIIGA JmjC PF02373.22 CRJ80635.1 - 3.9e-37 127.2 0.5 3.9e-37 127.2 0.5 2.0 2 0 0 2 2 2 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.6 CRJ80635.1 - 7.1e-19 68.0 9.3 1.4e-18 67.0 9.3 1.5 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 CRJ80635.1 - 4.2e-18 65.4 8.9 4.2e-18 65.4 8.9 2.5 2 0 0 2 2 2 1 PHD-like zinc-binding domain JmjN PF02375.17 CRJ80635.1 - 3e-15 55.9 0.6 7.5e-15 54.6 0.6 1.7 1 0 0 1 1 1 1 jmjN domain Cellulase PF00150.18 CRJ80638.1 - 1.5e-16 60.7 6.6 2.6e-16 59.9 6.6 1.3 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.15 CRJ80638.1 - 0.0094 15.3 0.1 0.027 13.8 0.0 1.7 2 0 0 2 2 2 1 Beta-galactosidase Glyco_hydro_2_C PF02836.17 CRJ80638.1 - 0.021 13.9 0.0 0.06 12.5 0.0 1.7 1 1 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain DUF4038 PF13204.6 CRJ80638.1 - 0.13 11.9 9.4 0.33 10.5 9.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4038) DUF1479 PF07350.12 CRJ80641.1 - 1.7e-165 550.9 0.0 2.1e-165 550.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.13 CRJ80641.1 - 0.024 14.9 1.6 5.3 7.2 0.0 2.6 3 0 0 3 3 3 0 Phytanoyl-CoA dioxygenase (PhyH) HpcH_HpaI PF03328.14 CRJ80641.1 - 0.11 11.6 0.0 0.21 10.7 0.0 1.4 1 0 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family GFO_IDH_MocA PF01408.22 CRJ80644.1 - 5.5e-15 56.2 0.0 8.8e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 CRJ80644.1 - 8.1e-05 22.6 0.0 0.00015 21.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain adh_short PF00106.25 CRJ80647.1 - 5.5e-35 120.6 0.0 1.2e-34 119.5 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRJ80647.1 - 1.2e-25 90.4 0.1 1.8e-25 89.9 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRJ80647.1 - 8.7e-11 42.1 0.1 1.3e-10 41.5 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CRJ80647.1 - 1.6e-07 31.0 0.1 3.1e-06 26.8 0.1 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family DUF2723 PF11028.8 CRJ80647.1 - 0.036 14.0 0.0 0.054 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2723) DUF1776 PF08643.10 CRJ80647.1 - 0.11 11.8 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) NmrA PF05368.13 CRJ80650.1 - 1.1e-50 172.4 0.8 2.8e-41 141.6 0.0 2.0 2 0 0 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.6 CRJ80650.1 - 8.4e-09 35.6 0.1 4.2e-06 26.8 0.0 2.2 2 0 0 2 2 2 2 NAD(P)H-binding Amidase PF01425.21 CRJ80652.1 - 6.7e-66 223.1 0.0 4.2e-64 217.2 0.0 2.1 1 1 0 1 1 1 1 Amidase HCV_NS5a PF01506.19 CRJ80652.1 - 0.21 11.5 0.1 0.21 11.5 0.1 1.9 2 0 0 2 2 2 0 Hepatitis C virus non-structural 5a protein membrane anchor p450 PF00067.22 CRJ80656.1 - 1.5e-66 225.0 0.0 2.3e-66 224.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 CRJ80656.1 - 2.5e-33 115.5 0.0 4.2e-33 114.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 CRJ80656.1 - 8.1e-26 90.9 0.0 8.2e-25 87.7 0.0 2.3 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 CRJ80656.1 - 8.8e-12 45.6 0.0 2.1e-11 44.4 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 CRJ80656.1 - 0.14 12.4 0.0 0.44 10.8 0.0 1.8 2 0 0 2 2 2 0 Flavodoxin domain Peptidase_S8 PF00082.22 CRJ80661.1 - 7.7e-28 97.6 12.5 1.2e-27 96.9 12.4 1.3 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 CRJ80661.1 - 1.6e-18 67.1 0.1 3e-18 66.3 0.1 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 Epimerase PF01370.21 CRJ80665.1 - 1.4e-07 31.3 0.3 2.6e-06 27.1 0.3 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 CRJ80665.1 - 2.3e-06 27.6 0.1 4e-05 23.6 0.1 2.5 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 CRJ80665.1 - 8e-05 22.9 0.0 0.00014 22.1 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_4 PF07993.12 CRJ80665.1 - 0.00017 20.9 0.0 0.00033 19.9 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein NmrA PF05368.13 CRJ80665.1 - 0.00082 19.0 0.2 0.0021 17.7 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.19 CRJ80665.1 - 0.0013 17.8 0.0 0.032 13.2 0.0 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.20 CRJ80665.1 - 0.0024 17.9 0.0 0.007 16.4 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Zn_clus PF00172.18 CRJ80669.1 - 0.00024 21.2 10.9 0.0044 17.1 10.9 2.2 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain bZIP_2 PF07716.15 CRJ80669.1 - 0.0014 18.6 1.5 0.0014 18.6 1.5 2.2 2 0 0 2 2 2 1 Basic region leucine zipper DUF148 PF02520.17 CRJ80669.1 - 0.1 12.7 1.2 0.33 11.1 1.2 1.8 1 0 0 1 1 1 0 Domain of unknown function DUF148 Lar_N PF09861.9 CRJ80669.1 - 0.12 11.5 0.1 0.22 10.6 0.1 1.3 1 0 0 1 1 1 0 Lactate racemase N-terminal domain TMF_TATA_bd PF12325.8 CRJ80669.1 - 0.31 11.3 5.3 0.4 10.9 0.1 2.4 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding TSC22 PF01166.18 CRJ80669.1 - 0.34 11.2 1.4 3.8 7.9 0.1 2.5 2 0 0 2 2 2 0 TSC-22/dip/bun family BRE1 PF08647.11 CRJ80669.1 - 1.7 8.7 5.9 11 6.2 0.3 2.4 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase KGG PF10685.9 CRJ80672.1 - 9.3e-20 70.2 18.7 2.3e-10 40.4 0.8 3.6 3 0 0 3 3 3 3 Stress-induced bacterial acidophilic repeat motif zf-C2H2_jaz PF12171.8 CRJ80674.1 - 3.9e-14 52.5 18.0 3.8e-05 23.9 0.3 6.3 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CRJ80674.1 - 1e-13 51.1 19.8 0.00078 19.7 0.4 6.2 6 0 0 6 6 6 4 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 CRJ80674.1 - 4.4e-11 42.6 33.8 0.28 12.1 0.1 7.7 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2_2 PF12756.7 CRJ80674.1 - 4.4e-09 36.6 26.8 0.046 14.1 0.8 5.6 2 2 3 5 5 5 3 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 CRJ80674.1 - 1.1e-08 35.0 38.2 0.0061 17.0 0.1 7.1 7 1 0 7 7 7 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CRJ80674.1 - 0.006 17.0 1.0 0.15 12.5 0.1 6.7 7 0 0 7 7 7 3 Zinc-finger double domain Zn_ribbon_recom PF13408.6 CRJ80674.1 - 0.02 15.4 0.3 0.02 15.4 0.3 3.4 3 1 1 4 4 4 0 Recombinase zinc beta ribbon domain zf-C2H2_6 PF13912.6 CRJ80674.1 - 0.077 13.0 11.0 8.2 6.6 0.6 4.7 4 0 0 4 4 4 0 C2H2-type zinc finger AKAP95 PF04988.12 CRJ80674.1 - 0.59 10.4 11.1 0.35 11.1 0.2 3.4 3 1 0 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) Actin_micro PF17003.5 CRJ80674.1 - 0.6 9.2 5.3 8.9 5.4 2.4 2.6 1 1 1 2 2 2 0 Putative actin-like family Rad50_zn_hook PF04423.14 CRJ80674.1 - 2 8.3 0.0 2 8.3 0.0 3.8 4 1 1 5 5 5 0 Rad50 zinc hook motif zf-C2H2_11 PF16622.5 CRJ80674.1 - 4.1 7.3 18.3 2.5 7.9 0.2 5.0 5 0 0 5 5 5 0 zinc-finger C2H2-type Ribosomal_L32p PF01783.23 CRJ80677.1 - 1.4e-13 50.9 5.5 1.9e-13 50.4 5.5 1.2 1 0 0 1 1 1 1 Ribosomal L32p protein family zf-ribbon_3 PF13248.6 CRJ80677.1 - 0.0098 15.3 3.9 0.017 14.5 3.9 1.3 1 0 0 1 1 1 1 zinc-ribbon domain zinc-ribbons_6 PF07191.12 CRJ80677.1 - 0.019 14.9 1.3 0.027 14.4 1.3 1.3 1 0 0 1 1 1 0 zinc-ribbons Sgf11 PF08209.11 CRJ80677.1 - 0.14 11.8 4.0 1.3 8.6 0.1 2.3 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) SEO_C PF14577.6 CRJ80677.1 - 0.14 11.5 0.2 0.16 11.4 0.2 1.1 1 0 0 1 1 1 0 Sieve element occlusion C-terminus PolC_DP2 PF03833.13 CRJ80677.1 - 0.2 9.5 0.4 0.21 9.4 0.4 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 PhnA_Zn_Ribbon PF08274.12 CRJ80677.1 - 0.72 9.9 0.1 0.72 9.9 0.1 2.2 2 0 0 2 2 2 0 PhnA Zinc-Ribbon Septin PF00735.18 CRJ80680.1 - 6.2e-113 376.7 0.5 7.4e-113 376.5 0.5 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 CRJ80680.1 - 1.7e-07 31.3 0.0 3.2e-07 30.4 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 CRJ80680.1 - 1.8e-05 24.2 0.0 3.3e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.27 CRJ80680.1 - 4.2e-05 23.2 0.8 0.017 14.7 0.1 2.4 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CRJ80680.1 - 5.2e-05 23.2 0.1 0.0006 19.8 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 CRJ80680.1 - 0.0015 18.6 0.1 1.7 8.6 0.1 2.5 2 0 0 2 2 2 2 Dynamin family NB-ARC PF00931.22 CRJ80680.1 - 0.0034 16.6 0.1 0.0059 15.8 0.1 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_7 PF12775.7 CRJ80680.1 - 0.009 15.5 0.0 0.065 12.7 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_22 PF13401.6 CRJ80680.1 - 0.01 16.1 0.0 0.023 15.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CRJ80680.1 - 0.012 16.1 0.7 0.02 15.4 0.7 1.8 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 CRJ80680.1 - 0.016 15.6 0.0 0.041 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Gtr1_RagA PF04670.12 CRJ80680.1 - 0.019 14.3 0.1 0.52 9.6 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region FtsK_SpoIIIE PF01580.18 CRJ80680.1 - 0.075 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Microtub_bd PF16796.5 CRJ80680.1 - 0.096 12.6 0.3 0.55 10.2 0.1 2.1 2 0 0 2 2 2 0 Microtubule binding AAA_29 PF13555.6 CRJ80680.1 - 0.18 11.6 0.0 0.4 10.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Glyco_hydro_72 PF03198.14 CRJ80683.1 - 2.5e-113 378.5 0.1 3.2e-113 378.1 0.1 1.1 1 0 0 1 1 1 1 Glucanosyltransferase MFS_1 PF07690.16 CRJ80683.1 - 6.2e-32 110.9 55.8 3.7e-28 98.5 27.8 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.6 CRJ80683.1 - 1.6e-06 26.9 6.2 1.6e-06 26.9 6.2 3.1 2 1 1 3 3 3 2 MFS/sugar transport protein Carn_acyltransf PF00755.20 CRJ80686.1 - 2.4e-209 696.8 0.0 1.1e-208 694.6 0.0 1.8 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase XRCC4 PF06632.12 CRJ80686.1 - 0.056 12.3 0.4 0.13 11.1 0.0 1.7 2 0 0 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Adeno_E3_CR2 PF02439.15 CRJ80689.1 - 0.073 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Yip1 PF04893.17 CRJ80689.1 - 0.073 12.8 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Yip1 domain Rad51 PF08423.11 CRJ80692.1 - 4e-41 141.0 0.0 2.1e-40 138.6 0.0 1.8 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.6 CRJ80692.1 - 1.4e-07 31.3 0.0 3.2e-07 30.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain RecA PF00154.21 CRJ80692.1 - 2.3e-05 24.0 0.1 0.0042 16.6 0.0 2.2 2 0 0 2 2 2 2 recA bacterial DNA recombination protein ATPase PF06745.13 CRJ80692.1 - 5.8e-05 22.6 0.0 9.1e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 KaiC AAA_24 PF13479.6 CRJ80692.1 - 0.013 15.2 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 CRJ80692.1 - 0.031 14.3 0.0 0.54 10.3 0.0 2.5 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain DnaB_C PF03796.15 CRJ80692.1 - 0.04 13.3 0.0 0.88 8.8 0.0 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain NACHT PF05729.12 CRJ80692.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 CRJ80692.1 - 0.13 12.5 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain CTP_transf_like PF01467.26 CRJ80695.1 - 1.4e-05 25.3 0.0 6.1e-05 23.2 0.0 1.9 1 1 0 1 1 1 1 Cytidylyltransferase-like Fungal_trans PF04082.18 CRJ80698.1 - 2.4e-21 76.0 0.6 2.4e-21 76.0 0.6 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain p450 PF00067.22 CRJ80702.1 - 5.9e-53 180.2 0.0 8.6e-53 179.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF4536 PF15055.6 CRJ80702.1 - 0.19 12.0 0.5 0.45 10.8 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4536) Acetyltransf_1 PF00583.25 CRJ80705.1 - 0.00033 20.9 0.0 0.00074 19.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 CRJ80705.1 - 0.0054 17.4 0.1 0.014 16.0 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 CRJ80705.1 - 0.01 16.0 0.0 0.023 14.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain CBS PF00571.28 CRJ80708.1 - 9e-35 118.9 3.0 5.2e-09 36.4 0.0 5.3 4 0 0 4 4 4 4 CBS domain PB1 PF00564.24 CRJ80708.1 - 2.1e-07 30.8 0.3 5.5e-07 29.4 0.0 2.0 2 0 0 2 2 2 1 PB1 domain AAA_13 PF13166.6 CRJ80711.1 - 0.11 11.1 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain zf-C2H2 PF00096.26 CRJ80721.1 - 3.2e-05 24.1 32.1 0.0016 18.8 7.1 4.2 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CRJ80721.1 - 3.5e-05 24.0 7.9 0.0018 18.6 2.9 3.8 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CRJ80721.1 - 0.1 13.5 28.0 0.09 13.7 6.1 4.2 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 CRJ80721.1 - 0.1 12.3 8.6 1 9.2 2.7 2.7 2 0 0 2 2 2 0 zinc-finger C2H2-type ABC2_membrane PF01061.24 CRJ80724.1 - 3e-83 278.4 39.2 3.6e-46 157.2 19.9 2.5 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 CRJ80724.1 - 2.2e-38 131.9 0.0 1.1e-19 71.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 CRJ80724.1 - 1.3e-29 101.9 0.1 1.2e-24 86.0 0.0 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 CRJ80724.1 - 1.7e-12 47.2 27.9 2.2e-07 30.3 11.5 2.6 2 1 0 2 2 2 2 ABC-2 family transporter protein ABC_trans_N PF14510.6 CRJ80724.1 - 2.7e-07 31.1 0.1 6.8e-07 29.8 0.1 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_25 PF13481.6 CRJ80724.1 - 8.2e-05 22.3 0.0 0.032 13.8 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CRJ80724.1 - 0.00028 21.3 0.1 0.067 13.6 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 CRJ80724.1 - 0.00039 20.3 0.3 0.0062 16.4 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 CRJ80724.1 - 0.00054 19.6 0.5 0.086 12.6 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 CRJ80724.1 - 0.00072 20.1 0.0 1.8 9.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 CRJ80724.1 - 0.0011 18.9 0.0 2 8.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 CRJ80724.1 - 0.0011 19.1 0.0 1.4 9.1 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.6 CRJ80724.1 - 0.0031 17.8 0.3 0.64 10.3 0.2 3.5 3 1 0 3 3 3 1 AAA domain PduV-EutP PF10662.9 CRJ80724.1 - 0.012 15.4 0.3 7.6 6.3 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.6 CRJ80724.1 - 0.013 15.7 0.6 0.72 10.1 0.4 2.4 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 CRJ80724.1 - 0.017 15.6 0.0 1.1 9.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 CRJ80724.1 - 0.023 14.3 0.6 2 8.0 0.4 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 CRJ80724.1 - 0.058 13.1 0.1 5 6.8 0.3 2.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 CRJ80724.1 - 0.088 12.7 0.4 2.8 7.9 0.2 2.4 2 0 0 2 2 2 0 NACHT domain Zn_clus PF00172.18 CRJ80726.1 - 0.00012 22.2 8.9 0.00019 21.5 8.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WSC PF01822.19 CRJ80732.1 - 1.1e-12 47.9 13.5 2.1e-12 47.1 13.5 1.5 1 0 0 1 1 1 1 WSC domain SKG6 PF08693.10 CRJ80732.1 - 0.00012 21.4 4.0 0.00021 20.6 4.0 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Podoplanin PF05808.11 CRJ80732.1 - 0.025 14.7 0.4 0.037 14.1 0.4 1.2 1 0 0 1 1 1 0 Podoplanin PepSY_TM PF03929.16 CRJ80732.1 - 0.097 12.3 0.1 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 PepSY-associated TM region DUF2749 PF10907.8 CRJ80732.1 - 0.1 12.8 0.5 0.32 11.2 0.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) PTP_tm PF18861.1 CRJ80732.1 - 0.13 12.3 3.3 0.23 11.4 3.3 1.4 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J DUF4470 PF14737.6 CRJ80734.1 - 1.2e-22 79.9 0.1 3.4e-22 78.4 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4470) ECH_1 PF00378.20 CRJ80740.1 - 1.5e-36 126.0 0.0 2.6e-27 95.7 0.0 3.1 3 0 0 3 3 3 3 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CRJ80740.1 - 1e-20 74.5 0.1 5.7e-17 62.2 0.0 2.3 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase PAS PF00989.25 CRJ80740.1 - 0.083 12.9 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 PAS fold Kelch_5 PF13854.6 CRJ80743.1 - 4.2e-11 42.6 0.1 5.1e-08 32.7 0.0 3.6 4 0 0 4 4 4 2 Kelch motif Ank_2 PF12796.7 CRJ80743.1 - 8.7e-09 35.9 0.0 1.5e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CRJ80743.1 - 1.8e-08 34.5 0.0 5.2e-08 33.0 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 CRJ80743.1 - 5.6e-08 32.9 0.0 2.8e-06 27.5 0.1 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 CRJ80743.1 - 3.3e-06 27.5 0.1 0.00028 21.4 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CRJ80743.1 - 1.7e-05 24.8 0.0 0.00039 20.7 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Yip1 PF04893.17 CRJ80743.1 - 0.039 13.7 0.0 0.068 12.9 0.0 1.3 1 0 0 1 1 1 0 Yip1 domain SKG6 PF08693.10 CRJ80743.1 - 0.049 13.0 1.5 0.094 12.1 1.5 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Peptidase_S10 PF00450.22 CRJ80747.1 - 1e-71 242.6 0.0 1.5e-71 242.0 0.0 1.2 1 1 0 1 1 1 1 Serine carboxypeptidase Peptidase_S10 PF00450.22 CRJ80750.1 - 2.3e-34 119.5 0.2 2.8e-34 119.3 0.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase DUF4964 PF16334.5 CRJ80750.1 - 0.17 11.5 0.0 0.34 10.5 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4964) Rft-1 PF04506.13 CRJ80753.1 - 0.0031 16.3 3.4 0.0038 16.1 3.4 1.1 1 0 0 1 1 1 1 Rft protein Peptidase_S10 PF00450.22 CRJ80756.1 - 1.8e-13 50.7 0.0 1.9e-13 50.6 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Glyco_hydro_12 PF01670.16 CRJ80758.1 - 2.7e-45 155.0 7.3 3.1e-45 154.8 7.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 FAD_binding_3 PF01494.19 CRJ80760.1 - 1.2e-07 31.4 1.0 0.037 13.3 0.1 3.2 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.6 CRJ80760.1 - 0.0089 16.2 0.0 0.018 15.2 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CRJ80760.1 - 0.031 13.5 0.0 0.049 12.9 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CRJ80760.1 - 0.042 13.9 0.0 0.082 12.9 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding DAO PF01266.24 CRJ80760.1 - 0.055 13.1 0.1 0.091 12.3 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Phospholip_A2_3 PF09056.11 CRJ80762.1 - 2.2e-43 147.4 0.5 2.8e-43 147.1 0.5 1.1 1 0 0 1 1 1 1 Prokaryotic phospholipase A2 Oxidored_FMN PF00724.20 CRJ80765.1 - 2.2e-82 277.1 0.0 2.5e-82 276.9 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family APH PF01636.23 CRJ81236.1 - 0.00032 20.7 0.2 0.00058 19.9 0.2 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Velvet PF11754.8 CRJ81240.1 - 1.7e-37 129.7 3.9 2.2e-27 96.6 0.1 2.7 1 1 2 3 3 3 2 Velvet factor Hira PF07569.11 CRJ81246.1 - 5.7e-84 281.3 0.3 1.9e-83 279.6 0.0 2.0 2 0 0 2 2 2 1 TUP1-like enhancer of split WD40 PF00400.32 CRJ81246.1 - 6e-29 99.7 24.4 4.9e-05 24.0 0.3 8.8 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRJ81246.1 - 3.7e-16 59.2 0.4 0.022 15.1 0.0 6.6 4 1 3 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 CRJ81246.1 - 9.1e-10 38.2 0.5 9.1e-10 38.2 0.5 2.1 2 0 0 2 2 2 1 HIRA B motif Ribonuclease PF00545.20 CRJ81246.1 - 3.7e-08 34.0 0.0 1e-07 32.5 0.0 1.8 1 0 0 1 1 1 1 ribonuclease PD40 PF07676.12 CRJ81246.1 - 4.9e-06 26.3 0.4 5.1 7.1 0.0 4.9 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 CRJ81246.1 - 0.0069 15.4 2.3 0.42 9.5 0.0 4.0 4 1 1 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein RNA_pol_Rpc4 PF05132.14 CRJ81246.1 - 0.039 14.4 7.9 0.081 13.3 7.9 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 IKI3 PF04762.12 CRJ81246.1 - 0.067 11.2 0.1 0.29 9.1 0.0 2.0 3 0 0 3 3 3 0 IKI3 family CDC45 PF02724.14 CRJ81246.1 - 0.075 11.3 1.8 0.11 10.8 1.8 1.2 1 0 0 1 1 1 0 CDC45-like protein LCD1 PF09798.9 CRJ81246.1 - 0.21 10.0 0.1 0.31 9.5 0.1 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein TAF4 PF05236.14 CRJ81246.1 - 0.3 10.8 11.3 0.56 9.9 11.3 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family POM121 PF15229.6 CRJ81246.1 - 0.43 10.2 11.5 0.91 9.1 11.5 1.5 1 0 0 1 1 1 0 POM121 family Tim54 PF11711.8 CRJ81246.1 - 1.9 7.2 8.8 3 6.5 8.8 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RR_TM4-6 PF06459.12 CRJ81246.1 - 2 8.2 17.4 3.3 7.5 17.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Elongin_A PF06881.11 CRJ81250.1 - 2.2 8.8 6.9 0.93 10.0 2.6 2.2 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A DUF218 PF02698.17 CRJ81255.1 - 3.8e-19 69.0 0.0 5.1e-19 68.6 0.0 1.1 1 0 0 1 1 1 1 DUF218 domain Hira PF07569.11 CRJ81258.1 - 3.1e-59 200.4 0.7 6.6e-59 199.3 0.0 1.9 2 0 0 2 2 2 1 TUP1-like enhancer of split WD40 PF00400.32 CRJ81258.1 - 7e-28 96.3 24.4 6.7e-05 23.6 0.3 8.8 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRJ81258.1 - 3.4e-15 56.1 0.4 0.03 14.6 0.0 6.5 4 1 3 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain DUF3425 PF11905.8 CRJ81258.1 - 4.6e-15 55.7 0.0 1.2e-14 54.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) HIRA_B PF09453.10 CRJ81258.1 - 1.2e-09 37.7 0.5 1.2e-09 37.7 0.5 2.2 2 0 0 2 2 2 1 HIRA B motif PD40 PF07676.12 CRJ81258.1 - 1.6e-05 24.7 0.4 6.9 6.7 0.0 4.9 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 CRJ81258.1 - 0.0078 15.2 0.9 0.63 8.9 0.0 3.6 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein RNA_pol_Rpc4 PF05132.14 CRJ81258.1 - 0.11 12.9 6.0 0.25 11.8 6.0 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 IKI3 PF04762.12 CRJ81258.1 - 0.11 10.4 0.0 0.34 8.8 0.0 1.8 2 0 0 2 2 2 0 IKI3 family DUF3484 PF11983.8 CRJ81258.1 - 3.3 8.9 5.3 11 7.3 5.3 1.8 1 0 0 1 1 1 0 Membrane-attachment and polymerisation-promoting switch Abhydrolase_6 PF12697.7 CRJ81258.1 - 9.7 6.7 14.7 0.1 13.2 4.3 3.1 3 1 0 3 3 2 0 Alpha/beta hydrolase family Ribonuclease PF00545.20 CRJ81263.1 - 1.8e-09 38.2 0.2 5.3e-09 36.7 0.0 1.7 1 1 1 2 2 2 1 ribonuclease DIM PF08194.12 CRJ81263.1 - 0.21 11.8 0.9 0.21 11.8 0.9 2.5 2 0 0 2 2 2 0 DIM protein ACC_epsilon PF13822.6 CRJ81263.1 - 1.9 9.2 6.1 10 6.9 6.1 2.0 1 1 0 1 1 1 0 Acyl-CoA carboxylase epsilon subunit Elongin_A PF06881.11 CRJ81266.1 - 0.026 15.0 2.0 0.026 15.0 2.0 2.3 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A BrnA_antitoxin PF14384.6 CRJ81266.1 - 8.1 7.0 7.8 2 9.0 2.3 2.7 2 2 0 2 2 2 0 BrnA antitoxin of type II toxin-antitoxin system DUF3425 PF11905.8 CRJ81271.1 - 8.6e-16 58.0 0.0 1.7e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Abhydrolase_6 PF12697.7 CRJ81276.1 - 4.7e-12 47.0 2.3 9.5e-12 46.0 2.3 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CRJ81276.1 - 4.9e-08 32.5 0.0 7e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CRJ81276.1 - 0.0001 22.0 0.0 0.00014 21.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 CRJ81276.1 - 0.00015 21.7 0.0 0.00023 21.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CRJ81276.1 - 0.093 12.2 0.0 1.7 8.0 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 CRJ81276.1 - 0.11 12.3 0.0 2.3 7.9 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Mu-like_Pro PF10123.9 CRJ81276.1 - 0.13 11.8 0.5 0.49 9.9 1.0 1.6 2 0 0 2 2 2 0 Mu-like prophage I protein TMEM189_B_dmain PF10520.9 CRJ81279.1 - 0.0099 16.0 0.1 0.018 15.2 0.1 1.5 1 0 0 1 1 1 1 B domain of TMEM189, localisation domain cobW PF02492.19 CRJ81286.1 - 1.4e-48 164.9 8.1 5.3e-37 127.1 0.9 2.2 1 1 1 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 CRJ81286.1 - 3e-16 59.1 0.1 1.4e-12 47.4 0.0 2.5 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain MeaB PF03308.16 CRJ81286.1 - 7.1e-06 25.2 0.2 0.0015 17.6 0.0 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 CRJ81286.1 - 0.0048 17.3 0.7 0.032 14.6 0.7 2.3 1 1 0 1 1 1 1 AAA ATPase domain Viral_helicase1 PF01443.18 CRJ81286.1 - 0.0077 16.0 0.1 0.015 15.0 0.1 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase MobB PF03205.14 CRJ81286.1 - 0.0096 15.8 0.1 0.024 14.5 0.1 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B TsaE PF02367.17 CRJ81286.1 - 0.011 15.7 0.0 0.03 14.3 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE GTP_EFTU PF00009.27 CRJ81286.1 - 0.029 13.9 2.4 0.73 9.3 0.1 2.5 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 CRJ81286.1 - 0.031 14.4 0.8 0.24 11.6 0.1 2.6 3 1 0 3 3 3 0 AAA domain AAA_18 PF13238.6 CRJ81286.1 - 0.1 13.1 0.4 1.4 9.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 CRJ81286.1 - 0.12 12.1 0.1 0.33 10.7 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain SHOCT PF09851.9 CRJ81291.1 - 0.086 12.6 0.4 0.086 12.6 0.4 3.2 4 0 0 4 4 4 0 Short C-terminal domain COesterase PF00135.28 CRJ81294.1 - 0.0072 15.2 0.0 0.0081 15.1 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family COesterase PF00135.28 CRJ81302.1 - 8e-39 133.9 0.0 9.8e-39 133.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Cutinase PF01083.22 CRJ81310.1 - 3.4e-48 164.0 0.0 4e-48 163.7 0.0 1.1 1 0 0 1 1 1 1 Cutinase Abhydrolase_2 PF02230.16 CRJ81310.1 - 0.023 14.5 0.1 0.033 14.0 0.1 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase VirJ PF06057.11 CRJ81310.1 - 0.089 12.7 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) DUF2974 PF11187.8 CRJ81310.1 - 0.14 11.7 0.0 0.18 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Mito_carr PF00153.27 CRJ81318.1 - 7.1e-66 218.2 0.8 1.5e-21 76.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CRJ81318.1 - 7.5 5.6 7.3 3.7 6.6 0.2 3.0 4 0 0 4 4 4 0 Gammaproteobacterial serine protease PTCB-BRCT PF12738.7 CRJ81322.1 - 0.074 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 twin BRCT domain IU_nuc_hydro PF01156.19 CRJ81327.1 - 7.2e-82 275.4 0.1 8.6e-82 275.1 0.1 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Glyco_hydro_3_C PF01915.22 CRJ81327.1 - 0.093 12.7 0.1 0.23 11.4 0.0 1.6 2 0 0 2 2 2 0 Glycosyl hydrolase family 3 C-terminal domain DUF2757 PF10955.8 CRJ81332.1 - 0.0069 16.6 2.6 0.012 15.9 1.1 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF2757) PhyH PF05721.13 CRJ81335.1 - 3.2e-09 37.4 0.0 1.1e-08 35.7 0.0 1.8 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Pyr_redox_2 PF07992.14 CRJ81343.1 - 7.3e-11 41.8 0.0 2.7e-08 33.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans_2 PF11951.8 CRJ81343.1 - 9.9e-11 41.1 0.4 1.3e-10 40.7 0.4 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain NAD_binding_9 PF13454.6 CRJ81343.1 - 0.00059 19.9 0.0 0.1 12.6 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 CRJ81343.1 - 0.016 14.8 1.1 0.053 13.1 0.2 2.3 3 0 0 3 3 3 0 FAD dependent oxidoreductase CCDC71L PF15374.6 CRJ81343.1 - 0.14 11.4 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L MCRA PF06100.11 CRJ81343.1 - 0.16 10.7 0.0 0.24 10.1 0.0 1.2 1 0 0 1 1 1 0 MCRA family Lycopene_cycl PF05834.12 CRJ81343.1 - 0.18 10.8 0.1 0.76 8.8 0.3 1.8 1 1 1 2 2 2 0 Lycopene cyclase protein peroxidase PF00141.23 CRJ81352.1 - 1.9e-20 73.6 0.5 3.4e-20 72.7 0.5 1.4 1 0 0 1 1 1 1 Peroxidase TauD PF02668.16 CRJ81356.1 - 5e-50 170.8 0.4 6.7e-50 170.4 0.4 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family ADH_zinc_N PF00107.26 CRJ81360.1 - 3.7e-08 33.4 1.9 6.5e-08 32.6 1.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Zn_clus PF00172.18 CRJ81360.1 - 5.4e-08 32.8 9.3 1.4e-07 31.5 9.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_N PF08240.12 CRJ81360.1 - 1.7e-07 31.1 1.3 3e-07 30.3 0.0 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 CRJ81360.1 - 6.4e-05 22.8 0.0 0.00017 21.4 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 CRJ81360.1 - 0.00088 20.3 0.0 0.003 18.6 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase zf-MYST PF17772.1 CRJ81360.1 - 0.099 12.3 3.1 0.17 11.5 3.1 1.4 1 0 0 1 1 1 0 MYST family zinc finger domain EspB PF05802.11 CRJ81360.1 - 2 8.4 4.9 4.7 7.1 0.9 2.5 3 0 0 3 3 3 0 Enterobacterial EspB protein WD40 PF00400.32 CRJ81368.1 - 3.4e-05 24.5 0.0 3.9 8.5 0.0 4.7 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRJ81368.1 - 0.00051 20.3 0.0 0.19 12.0 0.0 3.4 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain NAM-associated PF14303.6 CRJ81368.1 - 0.024 15.4 0.4 0.024 15.4 0.4 2.0 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain PD40 PF07676.12 CRJ81368.1 - 0.12 12.4 0.1 0.74 9.8 0.0 2.2 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat AF-4 PF05110.13 CRJ81368.1 - 0.87 7.6 6.0 1.2 7.2 6.0 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein F-box PF00646.33 CRJ81376.1 - 0.0001 22.0 3.4 0.00021 21.1 3.4 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 CRJ81376.1 - 0.046 13.6 2.8 0.11 12.4 2.8 1.7 1 0 0 1 1 1 0 F-box-like DUF5038 PF16441.5 CRJ81376.1 - 0.077 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5038) FAD_binding_3 PF01494.19 CRJ81379.1 - 1.4e-70 238.4 0.0 1.9e-41 142.5 0.0 2.1 1 1 1 2 2 2 2 FAD binding domain Phe_hydrox_dim PF07976.12 CRJ81379.1 - 8.7e-32 110.4 0.0 1.6e-31 109.6 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 CRJ81379.1 - 4.3e-08 32.8 0.0 0.00015 21.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CRJ81379.1 - 1.1e-05 25.8 0.1 0.0052 17.3 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CRJ81379.1 - 1.6e-05 23.8 0.5 4.6e-05 22.3 0.4 1.7 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 CRJ81379.1 - 0.00033 20.4 0.2 0.12 11.9 0.1 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CRJ81379.1 - 0.00042 20.5 0.1 0.001 19.2 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 CRJ81379.1 - 0.0015 17.7 0.5 0.0028 16.7 0.3 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 CRJ81379.1 - 0.0023 17.3 0.0 0.004 16.5 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 CRJ81379.1 - 0.005 16.0 0.2 0.008 15.3 0.2 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Trp_halogenase PF04820.14 CRJ81379.1 - 0.0079 15.1 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 Tryptophan halogenase Thi4 PF01946.17 CRJ81379.1 - 0.012 14.9 0.0 0.02 14.1 0.0 1.2 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 CRJ81379.1 - 0.038 13.1 0.2 0.072 12.1 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain UDPG_MGDP_dh_N PF03721.14 CRJ81379.1 - 0.062 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain XdhC_C PF13478.6 CRJ81379.1 - 0.1 13.1 0.0 0.25 11.9 0.0 1.7 1 0 0 1 1 1 0 XdhC Rossmann domain Pyr_redox_3 PF13738.6 CRJ81379.1 - 0.11 11.8 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CRJ81379.1 - 0.16 11.2 0.8 0.29 10.4 0.8 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 CRJ81379.1 - 0.24 11.3 0.0 0.39 10.6 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short PF00106.25 CRJ81384.1 - 3.5e-32 111.4 1.0 5e-32 110.9 0.4 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRJ81384.1 - 6.8e-24 84.7 0.6 9.6e-24 84.2 0.6 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRJ81384.1 - 8.2e-06 25.9 0.4 1.6e-05 24.9 0.3 1.5 1 1 0 1 1 1 1 KR domain DUF5378 PF17349.2 CRJ81384.1 - 0.068 12.5 0.0 0.097 12.0 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5378) Lysine_decarbox PF03641.14 CRJ81389.1 - 4.8e-28 97.9 0.0 8e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 CRJ81389.1 - 1.8e-08 34.1 0.6 3.1e-08 33.4 0.6 1.3 1 0 0 1 1 1 1 SLOG cluster4 family Fungal_trans PF04082.18 CRJ81392.1 - 0.0023 17.0 0.1 0.0039 16.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cep3 PF16846.5 CRJ81392.1 - 0.048 12.2 0.4 0.072 11.6 0.4 1.2 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit B PTPLA PF04387.14 CRJ81397.1 - 1.5e-47 161.4 13.5 2.5e-47 160.7 13.5 1.4 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Fructosamin_kin PF03881.14 CRJ81402.1 - 2.6e-29 102.4 0.0 3.3e-29 102.0 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase MFS_1 PF07690.16 CRJ81407.1 - 9e-39 133.4 29.2 9e-39 133.4 29.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily NACHT PF05729.12 CRJ81407.1 - 8.6e-09 35.5 0.1 1.8e-08 34.5 0.1 1.5 1 0 0 1 1 1 1 NACHT domain ANAPC4_WD40 PF12894.7 CRJ81407.1 - 1.3e-08 35.0 0.0 0.18 12.1 0.0 4.6 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CRJ81407.1 - 1.9e-07 31.6 0.1 0.93 10.5 0.0 6.5 6 0 0 6 6 6 2 WD domain, G-beta repeat PGAP1 PF07819.13 CRJ81407.1 - 1e-05 25.4 0.0 3e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 PGAP1-like protein Frtz PF11768.8 CRJ81407.1 - 0.00019 19.9 0.2 0.0024 16.3 0.0 2.1 2 0 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz Sugar_tr PF00083.24 CRJ81407.1 - 0.00021 20.3 6.7 0.00021 20.3 6.7 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter DUF676 PF05057.14 CRJ81407.1 - 0.00097 18.7 0.0 0.0023 17.5 0.0 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 CRJ81407.1 - 0.017 15.7 0.6 0.13 12.9 0.0 2.8 3 0 0 3 3 3 0 Alpha/beta hydrolase family DUF3464 PF11947.8 CRJ81407.1 - 0.024 14.4 0.2 0.064 13.0 0.2 1.7 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF2075 PF09848.9 CRJ81407.1 - 0.033 13.4 0.1 3.4 6.8 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) eIF2A PF08662.11 CRJ81407.1 - 0.073 12.9 0.0 0.36 10.7 0.0 2.1 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A LCAT PF02450.15 CRJ81407.1 - 0.1 11.8 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.8 CRJ81407.1 - 0.12 11.7 0.0 0.24 10.6 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Glyco_hydro_32N PF00251.20 CRJ81407.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 32 N-terminal domain MatE PF01554.18 CRJ81412.1 - 1.1e-52 178.0 26.5 7.8e-36 123.1 9.2 2.4 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 CRJ81412.1 - 0.0012 18.9 7.1 0.0012 18.9 7.1 3.8 3 2 0 3 3 3 2 Polysaccharide biosynthesis C-terminal domain DUF5389 PF17364.2 CRJ81412.1 - 0.012 15.6 0.2 0.012 15.6 0.2 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5389) Indigoidine_A PF04227.12 CRJ81417.1 - 1.7e-107 359.1 1.5 2.6e-107 358.5 1.5 1.3 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 CRJ81417.1 - 2.4e-20 73.0 3.3 3e-17 62.9 3.3 3.5 1 1 0 1 1 1 1 pfkB family carbohydrate kinase PMM PF03332.13 CRJ81422.1 - 2.3e-97 325.1 0.0 3.1e-97 324.7 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Na_Ca_ex PF01699.24 CRJ81422.1 - 9.6e-51 171.7 37.5 7.1e-27 94.2 19.2 2.6 2 0 0 2 2 2 2 Sodium/calcium exchanger protein p53-inducible11 PF14936.6 CRJ81422.1 - 0.012 15.6 6.4 0.14 12.2 2.7 2.9 2 1 0 2 2 2 0 Tumour protein p53-inducible protein 11 DUF5310 PF17237.2 CRJ81422.1 - 4.9 7.1 6.7 25 4.8 0.5 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5310) Cnd2 PF05786.14 CRJ81426.1 - 7.8e-258 858.1 0.2 2.5e-140 469.6 0.3 2.0 1 1 1 2 2 2 2 Condensin complex subunit 2 CNDH2_N PF06278.11 CRJ81426.1 - 0.0057 16.8 1.8 0.013 15.7 0.0 2.3 2 0 0 2 2 2 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal FAM176 PF14851.6 CRJ81426.1 - 9.1 5.9 11.2 20 4.8 2.4 3.4 4 0 0 4 4 4 0 FAM176 family HMG_box PF00505.19 CRJ81436.1 - 8.8e-16 58.1 0.1 1.6e-15 57.2 0.1 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CRJ81436.1 - 1.9e-12 47.6 0.1 3.6e-12 46.7 0.1 1.5 1 0 0 1 1 1 1 HMG-box domain SAM_1 PF00536.30 CRJ81436.1 - 3.8e-10 40.1 0.0 7.9e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 CRJ81436.1 - 6.5e-08 32.6 0.2 4.3e-07 30.0 0.0 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Phage_lysis PF03245.13 CRJ81436.1 - 0.058 13.5 0.2 0.13 12.4 0.2 1.5 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein WYL_3 PF18488.1 CRJ81436.1 - 0.3 11.5 5.3 0.81 10.1 5.3 1.7 1 0 0 1 1 1 0 WYL domain HalX PF08663.10 CRJ81445.1 - 0.13 12.6 0.7 0.2 12.0 0.7 1.2 1 0 0 1 1 1 0 HalX domain Methyltransf_23 PF13489.6 CRJ81449.1 - 4.2e-15 56.0 0.1 6.4e-15 55.4 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRJ81449.1 - 4e-14 53.1 0.1 2e-13 50.9 0.1 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CRJ81449.1 - 1.3e-13 51.4 0.1 6.8e-13 49.1 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRJ81449.1 - 1.5e-12 48.1 0.0 3.3e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRJ81449.1 - 5.2e-12 45.8 0.0 1.1e-11 44.8 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 CRJ81449.1 - 3.7e-08 33.0 0.0 9e-08 31.7 0.0 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 CRJ81449.1 - 0.00011 22.2 0.1 0.00026 21.0 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CRJ81449.1 - 0.0019 17.8 0.2 0.0044 16.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain TPMT PF05724.11 CRJ81449.1 - 0.014 15.1 0.1 0.029 14.0 0.0 1.5 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) CMAS PF02353.20 CRJ81449.1 - 0.068 12.4 0.1 0.12 11.6 0.1 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 CRJ81449.1 - 0.074 12.0 0.0 0.09 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) RrnaAD PF00398.20 CRJ81449.1 - 0.12 11.5 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_4 PF02390.17 CRJ81449.1 - 0.17 11.3 0.0 0.48 9.9 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase His_Phos_1 PF00300.22 CRJ81454.1 - 3.2e-35 121.6 4.0 7e-17 61.8 0.7 2.7 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) EDR1 PF14381.6 CRJ81459.1 - 0.08 12.7 0.2 0.29 10.8 0.0 1.8 2 0 0 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 DUF4615 PF15393.6 CRJ81459.1 - 0.64 10.6 4.8 0.47 11.0 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4615) DUF3801 PF12687.7 CRJ81459.1 - 0.96 9.5 7.9 6 6.9 7.9 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3801) ECM11 PF15463.6 CRJ81459.1 - 4.2 7.9 6.4 1 9.9 1.9 2.1 2 0 0 2 2 2 0 Extracellular mutant protein 11 UCH PF00443.29 CRJ81464.1 - 3.7e-47 161.0 0.0 5e-47 160.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CRJ81464.1 - 5.8e-12 45.8 5.2 7.5e-11 42.2 5.2 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 CRJ81464.1 - 1.1e-10 41.2 0.1 3.6e-10 39.4 0.0 2.0 3 0 0 3 3 3 1 Ubiquitin family ARPC4 PF05856.12 CRJ81469.1 - 1.3e-71 239.6 5.2 1.5e-71 239.3 5.2 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) SET PF00856.28 CRJ81476.1 - 1.3e-12 48.4 0.6 1.3e-12 48.4 0.6 3.1 2 1 0 2 2 2 1 SET domain AWS PF17907.1 CRJ81476.1 - 8.8e-07 28.9 6.9 8.8e-07 28.9 6.9 2.3 2 0 0 2 2 2 1 AWS domain CRAL_TRIO PF00650.20 CRJ81476.1 - 1.6e-06 27.9 0.0 4.1e-06 26.6 0.0 1.7 2 0 0 2 2 2 1 CRAL/TRIO domain IMS PF00817.20 CRJ81481.1 - 2.8e-40 137.7 0.0 4.7e-40 137.0 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family DHHC PF01529.20 CRJ81481.1 - 3.2e-27 95.3 3.2 3.2e-27 95.3 3.2 2.3 2 0 0 2 2 2 1 DHHC palmitoyltransferase zf_UBZ PF18439.1 CRJ81481.1 - 2.7e-11 42.8 5.0 7e-11 41.5 5.0 1.7 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger IMS_HHH PF11798.8 CRJ81481.1 - 0.0065 16.7 0.0 0.015 15.6 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif DUF3989 PF13150.6 CRJ81481.1 - 0.13 12.0 1.0 12 5.7 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3989) DUF485 PF04341.12 CRJ81481.1 - 0.76 9.8 7.5 0.72 9.9 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF485 zf-C2H2_4 PF13894.6 CRJ81481.1 - 3.8 8.6 4.9 1.2 10.2 0.8 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger IBN_N PF03810.19 CRJ81493.1 - 9.2e-14 51.1 2.6 1e-11 44.6 0.0 3.7 3 0 0 3 3 3 1 Importin-beta N-terminal domain Cse1 PF08506.10 CRJ81493.1 - 4.6e-07 29.0 1.0 1.7e-06 27.1 0.0 2.3 2 0 0 2 2 2 1 Cse1 Xpo1 PF08389.12 CRJ81493.1 - 5.4e-05 23.3 3.1 0.0014 18.7 0.3 3.6 3 0 0 3 3 3 1 Exportin 1-like protein GRIP PF01465.20 CRJ81493.1 - 0.0011 18.8 0.0 0.055 13.4 0.0 3.1 2 1 0 2 2 2 1 GRIP domain Importin_rep_6 PF18829.1 CRJ81493.1 - 0.017 15.2 0.1 0.092 12.9 0.1 2.4 1 0 0 1 1 1 0 Importin repeat 6 Cnd1 PF12717.7 CRJ81493.1 - 0.02 14.9 0.1 0.083 12.9 0.1 2.1 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CRJ81493.1 - 0.064 13.5 0.3 0.56 10.6 0.1 2.9 2 0 0 2 2 2 0 HEAT repeat Vac14_Fab1_bd PF12755.7 CRJ81493.1 - 0.07 13.7 2.5 0.67 10.6 0.1 3.6 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region ISN1 PF06437.11 CRJ81498.1 - 2.6e-130 435.0 0.0 1.9e-92 310.3 0.0 2.1 2 0 0 2 2 2 2 IMP-specific 5'-nucleotidase ISN1 PF06437.11 CRJ81509.1 - 3.2e-194 645.5 0.0 3.6e-194 645.4 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase DUF3450 PF11932.8 CRJ81513.1 - 0.011 15.1 3.7 0.011 15.1 3.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) CENP-F_leu_zip PF10473.9 CRJ81513.1 - 0.028 14.4 8.7 0.049 13.7 8.7 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BLOC1_2 PF10046.9 CRJ81513.1 - 0.094 13.0 2.5 0.22 11.9 2.5 1.6 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1515 PF07439.11 CRJ81513.1 - 0.46 10.5 1.7 1 9.4 1.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) Fib_alpha PF08702.10 CRJ81513.1 - 3.3 7.9 4.8 6.3 7.0 4.8 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family GBP_C PF02841.14 CRJ81513.1 - 8 5.8 10.8 12 5.2 10.8 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Med25_SD1 PF11235.8 CRJ81517.1 - 0.035 14.5 0.1 0.047 14.0 0.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 25 synapsin 1 Pkinase PF00069.25 CRJ81525.1 - 5.9e-48 163.5 0.0 7.8e-48 163.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRJ81525.1 - 6.5e-25 87.9 0.1 4.5e-24 85.1 0.1 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CRJ81525.1 - 0.043 13.1 0.0 0.13 11.6 0.0 1.7 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 CRJ81525.1 - 0.11 11.9 0.1 0.17 11.3 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CRJ81525.1 - 0.12 11.2 0.0 0.18 10.5 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 CRJ81529.1 - 1.1e-42 146.3 0.0 2.7e-42 145.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRJ81529.1 - 2.3e-22 79.6 0.1 9.8e-22 77.5 0.1 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CRJ81529.1 - 0.14 11.5 0.1 0.27 10.5 0.1 1.5 1 1 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 CRJ81529.1 - 0.15 10.8 0.0 0.31 9.8 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase Snf7 PF03357.21 CRJ81537.1 - 7.4e-07 28.9 24.5 7.4e-07 28.9 24.5 1.4 1 1 0 1 1 1 1 Snf7 Ist1 PF03398.14 CRJ81537.1 - 0.00018 21.4 6.5 0.00038 20.4 6.5 1.5 1 1 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway CEL_III_C PF18054.1 CRJ81537.1 - 4.5 7.3 6.9 7.2 6.7 6.9 1.4 1 0 0 1 1 1 0 CEL-III C-terminal PFEMP PF03011.15 CRJ81537.1 - 8.7 7.0 10.9 2 9.1 0.9 2.2 1 1 1 2 2 2 0 PFEMP DBL domain DSHCT PF08148.12 CRJ81542.1 - 1.3e-53 181.0 0.7 2.3e-53 180.2 0.2 1.7 2 0 0 2 2 2 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.6 CRJ81542.1 - 8e-24 85.0 0.0 1.3e-23 84.3 0.0 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 CRJ81542.1 - 1.3e-18 67.4 0.0 5.5e-18 65.3 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CRJ81542.1 - 2.2e-06 28.0 0.0 1.1e-05 25.7 0.0 2.2 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CRJ81542.1 - 3.2e-05 24.0 0.0 7.9e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Npa1 PF11707.8 CRJ81546.1 - 3.1e-20 72.8 0.1 6.4e-20 71.8 0.1 1.5 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 CRJ81546.1 - 6.3e-08 32.4 0.2 1.7e-07 31.0 0.2 1.8 1 0 0 1 1 1 1 Nucleolar pre-ribosomal-associated protein 1 Methyltransf_23 PF13489.6 CRJ81553.1 - 7.5e-05 22.6 0.0 0.049 13.5 0.0 2.1 1 1 1 2 2 2 2 Methyltransferase domain MTS PF05175.14 CRJ81553.1 - 0.0072 15.9 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain NDC10_II PF16787.5 CRJ81558.1 - 7.3e-10 38.4 0.0 4.4e-06 26.0 0.1 3.1 1 1 2 3 3 3 3 Centromere DNA-binding protein complex CBF3 subunit, domain 2 Methyltransf_11 PF08241.12 CRJ81564.1 - 4.6e-22 78.5 0.0 6.4e-22 78.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRJ81564.1 - 1.7e-20 73.5 0.0 2.2e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRJ81564.1 - 6.4e-18 65.0 0.0 8e-18 64.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CRJ81564.1 - 1.7e-12 47.2 0.0 2.3e-12 46.8 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 CRJ81564.1 - 7.4e-11 42.7 0.0 1.1e-10 42.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CRJ81564.1 - 2e-10 40.7 0.0 2.6e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CRJ81564.1 - 1.3e-09 37.8 0.0 1.6e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_29 PF03141.16 CRJ81564.1 - 0.0001 21.0 0.0 0.00013 20.7 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.14 CRJ81564.1 - 0.00014 21.4 0.0 0.00019 21.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 CRJ81564.1 - 0.00014 21.7 0.0 0.00018 21.3 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 CRJ81564.1 - 0.00074 19.0 0.0 0.00094 18.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.10 CRJ81564.1 - 0.001 18.6 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MetW PF07021.12 CRJ81564.1 - 0.0014 18.2 0.0 0.0018 17.9 0.0 1.1 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW RrnaAD PF00398.20 CRJ81564.1 - 0.009 15.1 0.0 0.01 14.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase TehB PF03848.14 CRJ81564.1 - 0.011 15.2 0.0 0.012 15.0 0.0 1.1 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_2 PF00891.18 CRJ81564.1 - 0.012 14.9 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_32 PF13679.6 CRJ81564.1 - 0.029 14.3 0.0 0.035 14.1 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.6 CRJ81564.1 - 0.082 13.9 0.0 0.11 13.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Glyco_hydro81C PF17652.1 CRJ81569.1 - 2.7e-159 530.1 9.3 3.4e-159 529.7 9.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 CRJ81569.1 - 1.1e-110 369.8 0.5 1.6e-110 369.3 0.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Oxidored_molyb PF00174.19 CRJ81575.1 - 9.3e-48 162.1 0.1 9.3e-47 158.8 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 CRJ81575.1 - 5.9e-21 74.9 3.3 1.3e-20 73.8 3.3 1.6 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain PAN_4 PF14295.6 CRJ81584.1 - 0.00065 19.5 0.3 0.0016 18.3 0.3 1.7 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 CRJ81584.1 - 0.0026 17.7 0.0 0.0061 16.5 0.0 1.6 1 0 0 1 1 1 1 PAN domain PhnA_Zn_Ribbon PF08274.12 CRJ81588.1 - 7.9 6.5 11.3 11 6.1 2.7 3.3 3 0 0 3 3 3 0 PhnA Zinc-Ribbon Pectate_lyase PF03211.13 CRJ81591.1 - 1.5e-29 103.0 1.5 1.9e-29 102.7 1.5 1.1 1 0 0 1 1 1 1 Pectate lyase SET PF00856.28 CRJ81596.1 - 1.7e-13 51.3 0.0 9.9e-13 48.8 0.0 2.0 1 1 0 1 1 1 1 SET domain TPR_MalT PF17874.1 CRJ81596.1 - 0.048 13.0 0.0 0.083 12.3 0.0 1.3 1 0 0 1 1 1 0 MalT-like TPR region PIP5K PF01504.18 CRJ81601.1 - 1.7e-44 152.1 0.0 1.4e-43 149.2 0.0 1.9 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Pam17 PF08566.10 CRJ81605.1 - 2e-62 209.9 0.0 3.5e-62 209.1 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 Chromo PF00385.24 CRJ81609.1 - 7.3e-08 32.2 0.1 3.8e-07 29.9 0.1 2.1 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain VIT1 PF01988.19 CRJ81609.1 - 0.024 14.5 0.3 0.053 13.4 0.3 1.5 1 1 0 1 1 1 0 VIT family ThiF PF00899.21 CRJ81614.1 - 3.7e-61 206.6 0.0 5.4e-61 206.0 0.0 1.3 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 CRJ81614.1 - 1e-12 48.5 0.0 2.6e-12 47.2 0.0 1.7 2 0 0 2 2 2 1 Rhodanese-like domain NAD_binding_7 PF13241.6 CRJ81614.1 - 0.043 14.2 0.0 0.1 13.0 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding ApbA PF02558.16 CRJ81614.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA CCDC144C PF14915.6 CRJ81614.1 - 0.15 11.1 0.1 0.25 10.4 0.1 1.2 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region RILP PF11461.8 CRJ81614.1 - 0.18 12.1 0.1 0.39 11.0 0.1 1.5 1 0 0 1 1 1 0 Rab interacting lysosomal protein FAD_binding_3 PF01494.19 CRJ81614.1 - 0.34 10.1 1.5 0.6 9.3 1.5 1.4 1 0 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.20 CRJ81614.1 - 0.53 10.3 3.4 1.2 9.2 0.1 2.4 2 1 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase SLX9 PF15341.6 CRJ81619.1 - 2e-37 128.5 1.5 2.6e-37 128.1 1.5 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 Cep57_CLD_2 PF14197.6 CRJ81619.1 - 0.1 12.7 0.3 0.3 11.2 0.4 1.6 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 Peptidase_C48 PF02902.19 CRJ81624.1 - 9.7e-10 38.6 0.1 1.4e-05 25.0 0.0 2.8 2 1 1 3 3 3 2 Ulp1 protease family, C-terminal catalytic domain AIG2_2 PF13772.6 CRJ81629.1 - 0.00087 19.6 0.0 0.0027 18.0 0.0 1.8 2 0 0 2 2 2 1 AIG2-like family PsbJ PF01788.17 CRJ81629.1 - 0.024 14.5 0.1 0.054 13.4 0.1 1.6 1 0 0 1 1 1 0 PsbJ RAM PF15320.6 CRJ81629.1 - 0.34 11.5 4.0 0.48 11.1 0.3 2.3 2 0 0 2 2 2 0 mRNA cap methylation, RNMT-activating mini protein EthD PF07110.11 CRJ81633.1 - 6.8e-07 30.4 0.3 7.5e-07 30.2 0.3 1.0 1 0 0 1 1 1 1 EthD domain ADH_zinc_N PF00107.26 CRJ81642.1 - 3.7e-27 94.9 0.2 6.6e-27 94.1 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CRJ81642.1 - 4.9e-25 89.1 0.0 1.3e-24 87.8 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CRJ81642.1 - 1.1e-05 25.2 0.1 3.1e-05 23.8 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 CRJ81642.1 - 0.0015 18.0 0.1 0.0021 17.6 0.1 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus PAF PF15715.5 CRJ81642.1 - 0.078 13.6 0.0 0.13 12.9 0.0 1.2 1 0 0 1 1 1 0 PCNA-associated factor histone like domain Egh16-like PF11327.8 CRJ81661.1 - 6.6e-53 179.9 9.6 7.9e-53 179.6 9.6 1.1 1 0 0 1 1 1 1 Egh16-like virulence factor p450 PF00067.22 CRJ81666.1 - 2.1e-43 148.7 0.0 3.2e-43 148.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.6 CRJ81679.1 - 1e-12 48.2 0.0 1.8e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRJ81679.1 - 9.3e-09 35.9 0.0 2e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CRJ81679.1 - 1.3e-08 35.3 0.0 3e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRJ81679.1 - 5.6e-06 26.2 0.0 0.00013 21.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRJ81679.1 - 1e-05 26.2 0.0 2.1e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain GSDH PF07995.11 CRJ81684.1 - 0.0016 17.9 0.9 0.067 12.5 0.2 3.3 2 1 1 3 3 3 1 Glucose / Sorbosone dehydrogenase NHL PF01436.21 CRJ81684.1 - 0.038 14.0 0.1 4.3 7.6 0.1 3.3 2 1 0 2 2 2 0 NHL repeat DUF4448 PF14610.6 CRJ81689.1 - 4.2e-30 105.0 0.0 6.7e-30 104.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) CENP-B_dimeris PF09026.10 CRJ81689.1 - 1.1e-05 25.7 7.8 2.2e-05 24.8 7.8 1.5 1 0 0 1 1 1 1 Centromere protein B dimerisation domain NOA36 PF06524.12 CRJ81689.1 - 0.013 14.8 10.9 0.022 14.1 10.9 1.3 1 0 0 1 1 1 0 NOA36 protein Consortin_C PF15281.6 CRJ81689.1 - 0.026 14.5 0.0 0.049 13.6 0.0 1.4 1 0 0 1 1 1 0 Consortin C-terminus DUF3377 PF11857.8 CRJ81689.1 - 0.03 14.2 0.0 0.077 12.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) RXT2_N PF08595.11 CRJ81689.1 - 0.045 13.8 2.2 0.084 12.9 2.2 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal SDA1 PF05285.12 CRJ81689.1 - 0.14 11.5 4.2 0.26 10.7 4.2 1.3 1 0 0 1 1 1 0 SDA1 GCIP PF13324.6 CRJ81689.1 - 0.16 11.6 0.7 0.24 11.0 0.7 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Osteopontin PF00865.18 CRJ81689.1 - 0.22 11.0 16.9 0.43 10.0 16.9 1.4 1 0 0 1 1 1 0 Osteopontin DUF4229 PF14012.6 CRJ81689.1 - 0.24 11.5 8.3 1 9.5 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) BUD22 PF09073.10 CRJ81689.1 - 0.39 10.0 3.0 0.51 9.6 3.0 1.1 1 0 0 1 1 1 0 BUD22 Sigma70_ner PF04546.13 CRJ81689.1 - 0.51 10.2 4.3 0.73 9.7 4.3 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region DNA_pol_phi PF04931.13 CRJ81689.1 - 1.3 7.0 13.7 1.9 6.5 13.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF2076 PF09849.9 CRJ81689.1 - 1.4 8.9 5.7 2.9 7.9 5.7 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Cwf_Cwc_15 PF04889.12 CRJ81689.1 - 2.3 7.9 15.6 4.1 7.1 15.6 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.14 CRJ81689.1 - 3.3 5.9 7.0 4.9 5.3 7.0 1.1 1 0 0 1 1 1 0 CDC45-like protein ANAPC15 PF15243.6 CRJ81689.1 - 3.6 8.1 12.8 7.2 7.1 12.8 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 RRN3 PF05327.11 CRJ81689.1 - 5 5.6 6.3 7.2 5.0 6.3 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 AA_permease_2 PF13520.6 CRJ81698.1 - 1.1e-45 156.2 50.3 1.4e-45 155.9 50.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CRJ81698.1 - 3e-33 115.1 45.7 3.9e-33 114.8 45.7 1.0 1 0 0 1 1 1 1 Amino acid permease GAPT PF11770.8 CRJ81698.1 - 0.028 14.3 0.5 0.062 13.2 0.5 1.5 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) AtuA PF07287.11 CRJ81703.1 - 2.6e-123 411.2 0.7 3.9e-123 410.6 0.7 1.2 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA AMP-binding PF00501.28 CRJ81703.1 - 2.3e-53 181.3 0.0 3.3e-53 180.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Peptidase_M28 PF04389.17 CRJ81703.1 - 1.8e-19 70.2 0.0 3.4e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 ABM PF03992.16 CRJ81703.1 - 2.1e-05 24.5 0.2 4.5e-05 23.5 0.2 1.5 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Peptidase_M20 PF01546.28 CRJ81703.1 - 0.07 12.8 0.0 0.64 9.7 0.0 2.3 2 0 0 2 2 2 0 Peptidase family M20/M25/M40 Nicastrin PF05450.15 CRJ81703.1 - 0.079 12.4 0.1 0.18 11.2 0.1 1.6 1 0 0 1 1 1 0 Nicastrin STAT2_C PF12188.8 CRJ81703.1 - 0.084 12.8 0.0 0.32 10.9 0.0 2.0 1 0 0 1 1 1 0 Signal transducer and activator of transcription 2 C terminal AtuA PF07287.11 CRJ81712.1 - 6e-113 377.1 0.3 9.4e-113 376.5 0.3 1.2 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA TRI12 PF06609.13 CRJ81712.1 - 7.2e-51 173.3 9.3 1.1e-50 172.7 9.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MaoC_dehydratas PF01575.19 CRJ81712.1 - 6.6e-24 83.8 0.2 2.2e-23 82.2 0.0 1.9 2 0 0 2 2 2 1 MaoC like domain MFS_1 PF07690.16 CRJ81712.1 - 2.5e-12 46.4 28.9 2.5e-12 46.4 27.4 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3425 PF11905.8 CRJ81718.1 - 4.6e-13 49.2 0.9 1.1e-12 48.0 0.9 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 CRJ81718.1 - 6.1e-05 23.0 7.3 0.063 13.4 2.6 2.3 1 1 1 2 2 2 2 bZIP transcription factor YabA PF06156.13 CRJ81718.1 - 0.008 16.8 0.1 0.008 16.8 0.1 1.8 2 0 0 2 2 1 1 Initiation control protein YabA MCC-bdg_PDZ PF10506.9 CRJ81718.1 - 0.03 14.3 2.1 0.2 11.7 2.4 2.0 1 1 1 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome FAM76 PF16046.5 CRJ81718.1 - 0.077 12.3 6.1 0.11 11.9 6.1 1.2 1 0 0 1 1 1 0 FAM76 protein DUF4201 PF13870.6 CRJ81718.1 - 0.089 12.5 5.6 0.13 12.0 5.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) ADIP PF11559.8 CRJ81718.1 - 0.13 12.3 9.5 0.28 11.3 9.5 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF812 PF05667.11 CRJ81718.1 - 0.21 10.4 6.6 0.38 9.6 6.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Csm1_N PF18504.1 CRJ81718.1 - 0.39 11.1 5.6 0.39 11.1 3.4 2.1 1 1 1 2 2 2 0 Csm1 N-terminal domain Nnf1 PF03980.14 CRJ81718.1 - 0.43 11.0 6.8 0.85 10.0 6.8 1.4 1 0 0 1 1 1 0 Nnf1 CREPT PF16566.5 CRJ81718.1 - 1 9.6 5.4 2.5 8.3 4.2 2.0 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour ZapB PF06005.12 CRJ81718.1 - 2.4 8.6 10.3 0.2 12.1 4.1 2.2 1 1 1 2 2 2 0 Cell division protein ZapB bZIP_2 PF07716.15 CRJ81718.1 - 6.2 7.0 10.8 0.38 10.9 1.0 2.4 1 1 1 2 2 2 0 Basic region leucine zipper adh_short_C2 PF13561.6 CRJ81722.1 - 1e-62 211.8 0.2 1.2e-62 211.5 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRJ81722.1 - 3.9e-43 147.2 0.1 4.9e-43 146.9 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CRJ81722.1 - 6.5e-08 32.7 0.5 9.1e-08 32.2 0.5 1.1 1 0 0 1 1 1 1 KR domain AtuA PF07287.11 CRJ81727.1 - 1.7e-46 158.6 0.1 2.9e-23 82.1 0.0 2.1 2 0 0 2 2 2 2 Acyclic terpene utilisation family protein AtuA SPW PF03779.14 CRJ81731.1 - 0.083 12.5 0.9 0.11 12.1 0.9 1.2 1 0 0 1 1 1 0 SPW repeat Glycos_transf_2 PF00535.26 CRJ81735.1 - 1.3e-20 73.9 0.0 2e-20 73.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 CRJ81735.1 - 2e-17 63.2 0.0 3e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.6 CRJ81735.1 - 8.2e-16 58.5 8.7 8.2e-16 58.5 8.7 2.8 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 CRJ81735.1 - 2.7e-13 50.3 0.0 3.9e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Cellulose_synt PF03552.14 CRJ81735.1 - 5e-07 28.6 0.4 0.017 13.6 0.1 2.8 1 1 2 3 3 3 2 Cellulose synthase Glyco_hydro_12 PF01670.16 CRJ81744.1 - 1.6e-11 44.6 5.9 3.6e-10 40.2 5.9 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 12 UDPG_MGDP_dh_N PF03721.14 CRJ81749.1 - 2.8e-49 167.2 0.0 4.2e-36 124.3 0.0 2.4 1 1 1 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 CRJ81749.1 - 2.7e-30 104.4 0.0 5.7e-30 103.4 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 CRJ81749.1 - 2e-20 73.2 0.0 9.2e-17 61.4 0.0 2.9 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Glyco_hydro_43 PF04616.14 CRJ81753.1 - 9.6e-35 120.3 0.7 1.2e-34 119.9 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 CRJ81753.1 - 2.5e-24 86.1 0.0 3.4e-24 85.7 0.0 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Collagen PF01391.18 CRJ81757.1 - 0.00034 20.3 15.9 0.00056 19.6 15.9 1.3 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) N_NLPC_P60 PF12912.7 CRJ81757.1 - 1.1 9.6 4.5 0.72 10.2 0.1 2.6 2 1 1 3 3 3 0 NLPC_P60 stabilising domain, N term RGS12_us1 PF16613.5 CRJ81760.1 - 6.5 7.1 7.8 8.8 6.7 0.8 2.6 2 0 0 2 2 2 0 Unstructured region of RGS12 Candida_ALS PF05792.13 CRJ81764.1 - 1.5e-30 105.4 324.7 0.00049 20.6 16.8 18.5 16 2 0 16 16 16 13 Candida agglutinin-like (ALS) Adhesin_Dr PF04619.12 CRJ81764.1 - 0.0085 16.0 0.0 0.0085 16.0 0.0 5.7 3 1 3 7 7 7 1 Dr-family adhesin WG_beta_rep PF14903.6 CRJ81764.1 - 0.028 14.7 0.0 32 4.9 0.0 4.2 3 0 0 3 3 3 0 WG containing repeat RFC1 PF08519.12 CRJ81768.1 - 0.14 12.3 6.2 0.15 12.2 6.2 1.2 1 0 0 1 1 1 0 Replication factor RFC1 C terminal domain WBP-1 PF11669.8 CRJ81768.1 - 2.1 9.0 4.4 2.3 8.9 4.4 1.1 1 0 0 1 1 1 0 WW domain-binding protein 1 DUF384 PF04064.13 CRJ81771.1 - 9.6 6.1 16.2 19 5.2 0.6 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF384) EMC3_TMCO1 PF01956.16 CRJ81775.1 - 1.3 8.7 7.6 1.6 8.5 7.6 1.1 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like ADH_N PF08240.12 CRJ81779.1 - 1.8e-29 101.8 1.4 3.3e-29 101.0 1.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain MFS_1 PF07690.16 CRJ81779.1 - 1.2e-27 96.8 21.1 1.2e-27 96.8 21.1 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily ADH_zinc_N PF00107.26 CRJ81779.1 - 2.2e-14 53.5 0.0 4.5e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 CRJ81779.1 - 7e-06 25.7 0.1 1.2e-05 24.9 0.1 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 CRJ81779.1 - 0.066 12.5 0.1 0.11 11.8 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Fungal_trans PF04082.18 CRJ81787.1 - 1.1e-20 73.8 0.6 1.9e-20 73.0 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRJ81787.1 - 0.00025 21.1 13.7 0.00094 19.3 13.7 2.0 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_88 PF07470.13 CRJ81792.1 - 2.2e-07 30.3 0.3 3.6e-07 29.6 0.3 1.3 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 DUF2264 PF10022.9 CRJ81795.1 - 2.5e-108 362.3 1.4 3.6e-108 361.8 1.4 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) MFS_1 PF07690.16 CRJ81795.1 - 1.6e-16 60.2 14.5 1.6e-16 60.2 14.5 2.2 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CRJ81795.1 - 0.0041 16.0 3.5 0.0041 16.0 3.5 2.1 1 1 0 2 2 2 1 Sugar (and other) transporter AIM24 PF01987.17 CRJ81801.1 - 2.4e-50 171.2 0.0 2.9e-50 170.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Kinesin PF00225.23 CRJ81805.1 - 7.6e-84 281.5 0.2 2.2e-72 243.8 0.0 2.7 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 CRJ81805.1 - 2.2e-16 60.1 0.0 1.2e-15 57.8 0.0 2.2 2 1 0 2 2 2 1 Microtubule binding DUF1514 PF07438.11 CRJ81805.1 - 0.0023 17.8 0.0 3.8 7.4 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF1514) AAA_22 PF13401.6 CRJ81805.1 - 0.005 17.1 0.1 16 5.8 0.0 3.8 3 0 0 3 3 3 1 AAA domain HHH_5 PF14520.6 CRJ81805.1 - 0.0077 16.8 0.0 0.93 10.1 0.0 2.7 2 0 0 2 2 2 1 Helix-hairpin-helix domain TrwB_AAD_bind PF10412.9 CRJ81805.1 - 0.035 13.0 0.0 5.2 5.9 0.0 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Zeta_toxin PF06414.12 CRJ81805.1 - 0.038 13.3 0.6 0.17 11.1 0.0 2.5 3 0 0 3 3 3 0 Zeta toxin CNOT1_HEAT PF16418.5 CRJ81805.1 - 0.11 12.6 0.6 18 5.4 0.0 2.8 3 0 0 3 3 3 0 CCR4-NOT transcription complex subunit 1 HEAT repeat Attacin_N PF03768.15 CRJ81805.1 - 0.19 11.9 2.8 14 5.9 0.2 2.7 2 0 0 2 2 2 0 Attacin, N-terminal region DUF87 PF01935.17 CRJ81805.1 - 0.21 11.6 9.5 0.21 11.7 0.1 4.0 4 1 0 4 4 4 0 Helicase HerA, central domain DUF4072 PF13284.6 CRJ81805.1 - 0.78 10.2 4.5 48 4.5 0.0 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4072) HATPase_c PF02518.26 CRJ81811.1 - 4.1e-23 82.0 0.0 9.7e-23 80.8 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 CRJ81811.1 - 1.8e-17 63.5 1.4 3.1e-17 62.8 0.6 1.8 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 CRJ81811.1 - 3.3e-06 27.0 1.5 5.2e-06 26.4 0.0 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 CRJ81811.1 - 6.5e-05 23.2 0.0 0.019 15.2 0.0 3.2 3 0 0 3 3 3 1 PAS fold PAS PF00989.25 CRJ81811.1 - 0.0014 18.6 0.0 0.0037 17.3 0.0 1.8 1 0 0 1 1 1 1 PAS fold HATPase_c_3 PF13589.6 CRJ81811.1 - 0.11 12.3 0.0 0.96 9.3 0.0 2.3 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FAD_binding_4 PF01565.23 CRJ81821.1 - 1.4e-19 70.3 0.2 2.8e-19 69.2 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 CRJ81821.1 - 3.4e-09 36.7 0.2 8.3e-09 35.4 0.2 1.6 1 0 0 1 1 1 1 Berberine and berberine like ALO PF04030.14 CRJ81821.1 - 0.027 14.3 0.2 0.056 13.3 0.2 1.4 1 0 0 1 1 1 0 D-arabinono-1,4-lactone oxidase NAD_binding_4 PF07993.12 CRJ81825.1 - 2.7e-44 151.3 0.1 4.9e-44 150.4 0.1 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 CRJ81825.1 - 4.5e-39 134.2 0.0 7.4e-39 133.5 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AAA_33 PF13671.6 CRJ81825.1 - 3.4e-11 43.5 0.0 9.5e-11 42.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain Epimerase PF01370.21 CRJ81825.1 - 6.2e-11 42.2 0.0 1.4e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 CRJ81825.1 - 3.2e-10 40.2 0.6 3.6e-09 36.8 0.1 2.9 3 0 0 3 3 3 1 Phosphopantetheine attachment site SKI PF01202.22 CRJ81825.1 - 6e-09 36.2 0.0 1.4e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 Shikimate kinase KR PF08659.10 CRJ81825.1 - 1.6e-06 28.2 0.6 6.1e-06 26.3 0.6 2.0 1 0 0 1 1 1 1 KR domain AAA_18 PF13238.6 CRJ81825.1 - 2.6e-05 24.8 0.0 8.2e-05 23.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 CRJ81825.1 - 3.3e-05 23.8 0.1 0.00015 21.7 0.0 2.1 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein APS_kinase PF01583.20 CRJ81825.1 - 0.00016 21.6 0.0 0.00035 20.5 0.0 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_17 PF13207.6 CRJ81825.1 - 0.00018 21.9 0.0 0.00048 20.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 CRJ81825.1 - 0.0014 18.0 0.1 0.0077 15.5 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin Cytidylate_kin PF02224.18 CRJ81825.1 - 0.0031 17.3 0.0 0.0069 16.2 0.0 1.6 1 0 0 1 1 1 1 Cytidylate kinase AAA_PrkA PF08298.11 CRJ81825.1 - 0.0037 16.2 0.0 0.0063 15.5 0.0 1.2 1 0 0 1 1 1 1 PrkA AAA domain AAA_16 PF13191.6 CRJ81825.1 - 0.0052 17.2 0.5 0.028 14.8 0.1 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 CRJ81825.1 - 0.007 16.8 0.0 0.036 14.5 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) 3Beta_HSD PF01073.19 CRJ81825.1 - 0.013 14.5 0.0 0.058 12.4 0.0 1.9 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family T2SSE PF00437.20 CRJ81825.1 - 0.017 14.2 0.4 0.12 11.4 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein ABC_tran PF00005.27 CRJ81825.1 - 0.027 15.0 0.0 0.075 13.5 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Semialdhyde_dh PF01118.24 CRJ81825.1 - 0.027 14.9 0.0 0.077 13.4 0.0 1.8 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Cytidylate_kin2 PF13189.6 CRJ81825.1 - 0.027 14.6 0.2 0.097 12.8 0.0 2.0 2 0 0 2 2 2 0 Cytidylate kinase-like family CoaE PF01121.20 CRJ81825.1 - 0.033 13.9 0.0 0.069 12.8 0.0 1.5 1 0 0 1 1 1 0 Dephospho-CoA kinase AAA_25 PF13481.6 CRJ81825.1 - 0.043 13.4 0.3 0.16 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain dNK PF01712.19 CRJ81825.1 - 0.067 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Deoxynucleoside kinase RNA12 PF10443.9 CRJ81825.1 - 0.071 11.8 0.0 0.13 10.9 0.0 1.3 1 0 0 1 1 1 0 RNA12 protein AAA_22 PF13401.6 CRJ81825.1 - 0.072 13.4 0.0 0.43 10.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 CRJ81825.1 - 0.1 12.5 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase Rad17 PF03215.15 CRJ81825.1 - 0.14 12.1 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_29 PF13555.6 CRJ81825.1 - 0.16 11.7 0.0 0.48 10.2 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain DapB_N PF01113.20 CRJ81825.1 - 0.17 12.0 0.0 0.8 9.8 0.0 2.2 2 0 0 2 2 1 0 Dihydrodipicolinate reductase, N-terminus NB-ARC PF00931.22 CRJ81825.1 - 0.18 11.0 0.0 0.35 10.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain NmrA PF05368.13 CRJ81825.1 - 0.18 11.3 0.1 0.36 10.3 0.1 1.5 1 0 0 1 1 1 0 NmrA-like family Aldo_ket_red PF00248.21 CRJ81829.1 - 4.3e-47 160.7 0.0 4.8e-46 157.3 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Fungal_trans PF04082.18 CRJ81832.1 - 2.3e-28 99.0 0.0 3.4e-28 98.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRJ81832.1 - 5.6e-08 32.8 8.3 9.8e-08 32.0 8.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 CRJ81834.1 - 1.1e-24 87.1 23.0 1.1e-24 87.1 23.0 2.8 2 1 2 4 4 4 2 Major Facilitator Superfamily RrnaAD PF00398.20 CRJ81834.1 - 9.9e-05 21.5 0.0 0.00031 19.9 0.0 1.8 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase SHOCT PF09851.9 CRJ81834.1 - 0.26 11.1 2.9 0.72 9.7 0.3 2.8 2 0 0 2 2 2 0 Short C-terminal domain Glyco_transf_90 PF05686.12 CRJ81838.1 - 1e-14 54.3 3.2 1.2e-09 37.6 0.0 2.9 3 0 0 3 3 3 2 Glycosyl transferase family 90 Glyco_transf_90 PF05686.12 CRJ81840.1 - 2.4e-10 39.9 2.0 1.1e-09 37.8 0.0 2.4 3 0 0 3 3 3 1 Glycosyl transferase family 90 RTA1 PF04479.13 CRJ81842.1 - 6.5e-60 202.3 8.9 6.5e-60 202.3 8.9 2.2 2 0 0 2 2 2 1 RTA1 like protein Fungal_trans_2 PF11951.8 CRJ81842.1 - 8.7e-09 34.7 0.3 1.6e-08 33.8 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRJ81842.1 - 0.00071 19.6 0.4 0.0013 18.8 0.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IBR PF01485.21 CRJ81843.1 - 1.5e-20 73.1 45.1 2.8e-11 43.5 4.2 4.3 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 CRJ81843.1 - 3e-07 30.2 40.3 0.00012 21.9 6.6 4.3 3 1 1 4 4 4 3 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CRJ81843.1 - 5.8e-05 23.3 42.6 0.00022 21.5 5.2 3.9 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 CRJ81843.1 - 0.0026 17.6 42.4 0.048 13.5 3.1 4.9 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CRJ81843.1 - 0.042 13.9 32.9 0.17 11.9 4.5 3.9 3 1 0 3 3 3 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 CRJ81843.1 - 0.044 13.9 1.2 0.044 13.9 1.2 4.6 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 CRJ81843.1 - 0.19 12.0 34.5 1.8 8.9 2.9 3.5 3 0 0 3 3 3 0 RING-H2 zinc finger domain Dermcidin PF15291.6 CRJ81845.1 - 0.25 11.9 3.9 0.32 11.6 3.9 1.1 1 0 0 1 1 1 0 Dermcidin, antibiotic peptide Orf78 PF06024.12 CRJ81845.1 - 1.5 9.1 6.7 2.1 8.7 6.7 1.2 1 0 0 1 1 1 0 Orf78 (ac78) Presenilin PF01080.17 CRJ81845.1 - 3.7 6.2 6.1 3.5 6.3 6.1 1.0 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 CRJ81845.1 - 4.5 5.8 5.1 4.8 5.8 5.1 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup XPG_I PF00867.18 CRJ81846.1 - 1.6e-22 79.6 0.0 4.2e-22 78.3 0.0 1.8 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 CRJ81846.1 - 3.8e-22 78.6 0.0 1.1e-21 77.2 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain IBR PF01485.21 CRJ81846.1 - 9.5e-18 64.2 47.2 1.3e-10 41.3 4.2 4.8 4 1 1 5 5 5 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 CRJ81846.1 - 1.5e-05 24.7 38.4 0.00067 19.5 6.4 3.9 3 1 0 3 3 3 3 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CRJ81846.1 - 0.00093 19.5 5.3 0.00093 19.5 5.3 3.7 2 1 1 3 3 3 1 Ring finger domain XPG_I_2 PF12813.7 CRJ81846.1 - 0.0017 17.9 0.0 0.0017 17.9 0.0 2.2 3 0 0 3 3 3 1 XPG domain containing Trp_syntA PF00290.20 CRJ81846.1 - 0.18 10.6 0.0 0.32 9.8 0.0 1.3 1 0 0 1 1 1 0 Tryptophan synthase alpha chain zf-C3HC4_2 PF13923.6 CRJ81846.1 - 0.22 11.4 40.6 0.19 11.6 3.1 4.5 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) Tma16 PF11176.8 CRJ81847.1 - 5.7e-46 156.0 0.1 7.4e-46 155.7 0.1 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 MFS_1 PF07690.16 CRJ81848.1 - 1.2e-20 73.7 40.8 4.2e-13 48.9 20.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Chitin_bind_1 PF00187.19 CRJ81849.1 - 1.3e-43 147.2 292.0 0.0001 22.7 18.7 11.8 11 0 0 11 11 11 11 Chitin recognition protein Glyco_transf_34 PF05637.12 CRJ81849.1 - 8.4e-08 32.2 0.5 1.8e-07 31.2 0.5 1.5 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Nucleotid_trans PF03407.16 CRJ81849.1 - 9.3e-07 29.0 0.7 1.8e-06 28.1 0.1 1.7 2 0 0 2 2 2 1 Nucleotide-diphospho-sugar transferase Glyco_hydro_18 PF00704.28 CRJ81851.1 - 5e-103 345.1 3.1 2.3e-51 175.4 0.3 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 CRJ81851.1 - 1.1e-05 25.8 8.4 1.1e-05 25.8 8.4 4.6 5 0 0 5 5 5 3 Chitin recognition protein Tgi2PP PF18250.1 CRJ81851.1 - 0.011 15.9 2.6 4 7.7 0.2 2.6 2 0 0 2 2 2 0 Effector immunity protein Tgi2PP RebB PF11747.8 CRJ81851.1 - 0.18 12.0 5.0 10 6.3 0.4 3.2 2 0 0 2 2 2 0 Killing trait Peptidase_M61 PF05299.12 CRJ81851.1 - 0.25 11.8 0.3 45 4.5 0.1 2.7 2 0 0 2 2 2 0 M61 glycyl aminopeptidase T3SS_needle_E PF08988.10 CRJ81851.1 - 0.29 11.3 0.3 43 4.4 0.0 2.6 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle Chitin_bind_1 PF00187.19 CRJ81852.1 - 2.1e-58 194.5 327.0 3.9e-07 30.4 21.5 12.8 12 0 0 12 12 12 12 Chitin recognition protein Sugar_tr PF00083.24 CRJ81853.1 - 5.3e-11 42.0 9.0 6.4e-11 41.8 9.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter DUF3021 PF11457.8 CRJ81853.1 - 0.48 10.8 5.2 0.65 10.3 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3021) Glyoxalase PF00903.25 CRJ82042.1 - 2.6e-22 79.4 0.1 8.9e-15 55.0 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 CRJ82042.1 - 1.8e-14 53.9 0.1 4.7e-07 30.1 0.1 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 CRJ82042.1 - 1.6e-06 28.3 0.0 0.071 13.2 0.0 3.1 3 0 0 3 3 3 2 Glyoxalase-like domain Glyoxalase_5 PF14696.6 CRJ82042.1 - 0.0013 18.9 0.1 0.0037 17.4 0.1 1.7 2 0 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal PNRC PF15365.6 CRJ82042.1 - 0.072 12.9 4.2 0.2 11.5 4.2 1.8 1 0 0 1 1 1 0 Proline-rich nuclear receptor coactivator motif NCE101 PF11654.8 CRJ82046.1 - 1.3e-09 37.6 0.0 1.4e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 Non-classical export protein 1 CPP1-like PF11833.8 CRJ82046.1 - 0.07 12.8 0.0 0.08 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Response_reg PF00072.24 CRJ82050.1 - 1.7e-33 115.1 0.7 5.8e-20 71.5 0.1 2.8 2 0 0 2 2 2 2 Response regulator receiver domain HATPase_c PF02518.26 CRJ82050.1 - 2.7e-33 114.8 0.5 1.5e-30 106.0 0.1 2.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AAA_16 PF13191.6 CRJ82050.1 - 1.5e-20 74.3 0.0 7.8e-12 45.9 0.0 3.0 2 0 0 2 2 2 2 AAA ATPase domain HisKA PF00512.25 CRJ82050.1 - 1.7e-17 63.2 1.3 4.4e-17 61.9 0.6 2.2 2 0 0 2 2 1 1 His Kinase A (phospho-acceptor) domain Pkinase PF00069.25 CRJ82050.1 - 2.1e-15 56.8 0.0 2e-06 27.4 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain GAF_2 PF13185.6 CRJ82050.1 - 1.3e-10 41.7 0.0 4.8e-10 39.9 0.0 2.1 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 CRJ82050.1 - 1e-08 35.9 0.1 5.6e-08 33.5 0.0 2.4 3 0 0 3 3 1 1 GAF domain NAD_binding_8 PF13450.6 CRJ82050.1 - 6.8e-08 32.6 0.1 1.8e-07 31.3 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pkinase_Tyr PF07714.17 CRJ82050.1 - 2.1e-06 27.2 0.0 0.058 12.7 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase AAA_22 PF13401.6 CRJ82050.1 - 6e-06 26.6 0.0 1.2 9.5 0.0 4.2 5 0 0 5 5 3 2 AAA domain NB-ARC PF00931.22 CRJ82050.1 - 1.1e-05 24.8 0.2 0.53 9.4 0.0 3.4 3 0 0 3 3 3 2 NB-ARC domain HATPase_c_3 PF13589.6 CRJ82050.1 - 3.3e-05 23.7 0.0 7.4e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MeaB PF03308.16 CRJ82050.1 - 0.00034 19.7 0.1 0.85 8.5 0.0 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB NACHT PF05729.12 CRJ82050.1 - 0.00045 20.2 0.0 2 8.3 0.0 3.1 3 0 0 3 3 2 2 NACHT domain AAA_14 PF13173.6 CRJ82050.1 - 0.002 18.2 0.0 4 7.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF2791 PF10923.8 CRJ82050.1 - 0.0094 14.8 0.2 4.5 6.0 0.0 2.6 2 0 0 2 2 2 2 P-loop Domain of unknown function (DUF2791) DUF2075 PF09848.9 CRJ82050.1 - 0.011 15.0 0.5 6.9 5.8 0.0 3.0 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) AAA_35 PF14516.6 CRJ82050.1 - 0.012 14.5 0.0 4.7 6.0 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain TPR_8 PF13181.6 CRJ82050.1 - 0.026 14.7 0.3 0.45 10.9 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA_33 PF13671.6 CRJ82050.1 - 0.039 14.1 0.0 19 5.4 0.0 2.9 2 0 0 2 2 2 0 AAA domain Pyr_redox_3 PF13738.6 CRJ82050.1 - 0.046 13.0 0.1 0.081 12.2 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CRJ82050.1 - 0.084 12.1 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CRJ82050.1 - 0.095 11.9 0.1 0.2 10.9 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain DUF2514 PF10721.9 CRJ82050.1 - 0.11 12.5 4.4 0.34 10.9 4.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Thi4 PF01946.17 CRJ82050.1 - 0.13 11.4 0.0 0.31 10.3 0.0 1.5 1 0 0 1 1 1 0 Thi4 family DAO PF01266.24 CRJ82050.1 - 0.14 11.7 0.0 0.32 10.5 0.0 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 CRJ82050.1 - 0.16 10.6 0.1 0.26 9.9 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Ribosomal_L27e PF01777.18 CRJ82050.1 - 0.47 10.9 2.0 1.5 9.3 2.0 1.9 1 0 0 1 1 1 0 Ribosomal L27e protein family TPR_MalT PF17874.1 CRJ82050.1 - 0.51 9.7 5.5 8.6 5.6 0.2 2.5 2 0 0 2 2 2 0 MalT-like TPR region TPR_2 PF07719.17 CRJ82050.1 - 6.4 7.2 5.8 23 5.4 0.0 4.0 4 0 0 4 4 2 0 Tetratricopeptide repeat DUF2722 PF10846.8 CRJ82058.1 - 0.00016 20.8 0.0 0.00016 20.8 0.0 3.4 2 1 1 3 3 3 2 Protein of unknown function (DUF2722) CAF-1_p150 PF11600.8 CRJ82058.1 - 0.0069 16.1 6.8 0.014 15.1 0.0 2.2 2 0 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Allantoicase PF03561.15 CRJ82063.1 - 1.3e-87 291.1 0.1 2.3e-45 154.1 0.0 2.9 2 0 0 2 2 2 2 Allantoicase repeat RabGAP-TBC PF00566.18 CRJ82063.1 - 1.6e-66 224.0 0.0 5.9e-32 111.1 0.0 2.3 2 0 0 2 2 2 2 Rab-GTPase-TBC domain DIL PF01843.19 CRJ82063.1 - 2.8e-30 104.7 0.4 5.2e-30 103.8 0.4 1.5 1 0 0 1 1 1 1 DIL domain Ank_2 PF12796.7 CRJ82063.1 - 3.6e-21 75.5 0.0 7.3e-13 48.9 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CRJ82063.1 - 4.1e-11 42.9 0.0 5.8e-06 26.5 0.0 2.8 1 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 CRJ82063.1 - 1.1e-09 38.3 0.1 0.00072 19.9 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 CRJ82063.1 - 3.1e-09 37.2 0.0 0.00041 20.8 0.0 3.2 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CRJ82063.1 - 4.9e-07 29.6 0.0 0.23 12.1 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat DPCD PF14913.6 CRJ82063.1 - 0.008 15.5 3.5 1.7 7.9 0.2 2.7 3 0 0 3 3 3 2 DPCD protein family Ribosomal_S13 PF00416.22 CRJ82063.1 - 0.058 13.8 0.7 14 6.1 0.1 2.5 2 0 0 2 2 2 0 Ribosomal protein S13/S18 SEN1_N PF12726.7 CRJ82063.1 - 0.15 10.3 0.8 7.4 4.7 0.0 2.6 3 0 0 3 3 3 0 SEN1 N terminal FGF-BP1 PF06473.12 CRJ82063.1 - 1.3 8.8 3.7 3.6 7.3 3.7 1.7 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) Cytochrom_B561 PF03188.16 CRJ82077.1 - 9.8e-17 61.4 6.3 1.7e-16 60.6 6.3 1.3 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF4006 PF13179.6 CRJ82077.1 - 0.16 11.9 0.1 0.16 11.9 0.1 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF4006) BPD_transp_2 PF02653.16 CRJ82077.1 - 1.7 7.7 13.3 0.084 12.0 4.5 2.0 2 0 0 2 2 2 0 Branched-chain amino acid transport system / permease component Claudin_2 PF13903.6 CRJ82077.1 - 3.1 7.5 7.0 2 8.1 0.1 2.3 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF4079 PF13301.6 CRJ82077.1 - 3.3 7.9 17.9 9.4 6.4 5.0 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF4079) DUF5336 PF17270.2 CRJ82077.1 - 5 6.7 14.0 0.019 14.6 2.2 2.5 2 1 1 3 3 3 0 Family of unknown function (DUF5336) MARVEL PF01284.23 CRJ82077.1 - 8.1 6.5 9.8 7.9 6.5 7.6 2.1 1 1 1 2 2 2 0 Membrane-associating domain Response_reg PF00072.24 CRJ82081.1 - 3.8e-14 52.8 0.0 4.3e-14 52.6 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain Peptidase_M28 PF04389.17 CRJ82086.1 - 9.3e-34 116.8 0.0 1.5e-33 116.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 CRJ82086.1 - 8.8e-13 48.1 0.3 1.8e-12 47.1 0.3 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 CRJ82086.1 - 4e-05 23.4 0.0 8e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 CRJ82086.1 - 0.074 12.1 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase Peptidase_S8 PF00082.22 CRJ82089.1 - 6.8e-40 137.2 3.2 1.1e-39 136.4 3.2 1.3 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 CRJ82089.1 - 5.3e-19 69.0 0.0 1e-18 68.1 0.0 1.5 1 0 0 1 1 1 1 Fn3-like domain NPCBM_assoc PF10633.9 CRJ82089.1 - 0.0034 17.6 1.5 0.011 16.0 0.2 2.6 2 0 0 2 2 2 1 NPCBM-associated, NEW3 domain of alpha-galactosidase FlgD_ig PF13860.6 CRJ82089.1 - 0.0095 15.8 0.0 0.049 13.5 0.0 2.3 1 0 0 1 1 1 1 FlgD Ig-like domain Peripla_BP_4 PF13407.6 CRJ82089.1 - 0.05 13.2 0.3 0.099 12.2 0.3 1.5 1 0 0 1 1 1 0 Periplasmic binding protein domain DUF4384 PF14326.6 CRJ82089.1 - 0.099 12.8 0.1 1.9 8.7 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4384) 4HBT PF03061.22 CRJ82089.1 - 0.15 12.4 0.1 0.59 10.5 0.0 2.1 2 0 0 2 2 2 0 Thioesterase superfamily Zn_clus PF00172.18 CRJ82094.1 - 0.13 12.4 1.9 0.39 10.9 1.9 1.8 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 CRJ82099.1 - 3.1e-30 105.1 0.0 4.3e-30 104.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Acyl-CoA_dh_M PF02770.19 CRJ82099.1 - 1.3e-19 70.2 0.0 2.6e-19 69.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 CRJ82099.1 - 1.3e-16 61.3 0.2 2.9e-16 60.1 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Abhydrolase_4 PF08386.10 CRJ82099.1 - 1.3e-07 31.7 0.0 5.3e-07 29.7 0.0 2.1 1 1 0 1 1 1 1 TAP-like protein Zn_clus PF00172.18 CRJ82099.1 - 3.1e-06 27.2 7.6 5.9e-06 26.3 7.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyl-CoA_dh_1 PF00441.24 CRJ82099.1 - 3.3e-06 27.4 0.2 6.9e-06 26.3 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Abhydrolase_1 PF00561.20 CRJ82099.1 - 0.00017 21.3 0.0 0.0004 20.1 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ribosomal_L37ae PF01780.19 CRJ82099.1 - 0.15 12.1 5.0 0.41 10.7 5.0 1.6 1 0 0 1 1 1 0 Ribosomal L37ae protein family Beta-lactamase PF00144.24 CRJ82107.1 - 1.8e-12 47.2 0.0 2.5e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase adh_short PF00106.25 CRJ82111.1 - 5.4e-36 123.9 0.0 7.9e-36 123.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRJ82111.1 - 1.1e-25 90.6 0.0 1.4e-25 90.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRJ82111.1 - 0.00013 21.9 0.1 0.00028 20.8 0.0 1.6 2 0 0 2 2 2 1 KR domain 2-Hacid_dh_C PF02826.19 CRJ82111.1 - 0.051 12.9 0.1 0.24 10.8 0.1 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 CRJ82111.1 - 0.053 13.0 0.4 0.14 11.6 0.4 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Phage_XkdX PF09693.10 CRJ82111.1 - 0.066 13.2 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 Phage uncharacterised protein (Phage_XkdX) ADH_zinc_N PF00107.26 CRJ82111.1 - 0.095 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase 3HCDH_N PF02737.18 CRJ82111.1 - 0.11 12.4 0.2 0.25 11.2 0.2 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 CRJ82111.1 - 0.17 12.1 0.2 7.2 6.9 0.1 2.2 2 0 0 2 2 2 0 TrkA-N domain KicB PF03882.14 CRJ82111.1 - 0.17 12.1 0.0 0.29 11.4 0.0 1.3 1 0 0 1 1 1 0 MukF winged-helix domain GMC_oxred_N PF00732.19 CRJ82115.1 - 6.9e-33 114.3 0.0 1.5e-19 70.5 0.0 2.5 1 1 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 CRJ82115.1 - 2.4e-15 57.3 0.0 4.6e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 CRJ82115.1 - 7.2e-10 38.5 0.0 0.00092 18.4 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 CRJ82115.1 - 9.4e-10 38.6 0.3 0.00028 20.6 0.1 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 CRJ82115.1 - 1.3e-08 34.0 0.0 1.3e-05 24.1 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.14 CRJ82115.1 - 4e-07 29.6 0.1 6.7e-05 22.3 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CRJ82115.1 - 2e-05 24.7 0.0 4.7e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 CRJ82115.1 - 0.00011 21.4 0.1 0.00017 20.8 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.7 CRJ82115.1 - 0.00034 20.1 0.1 0.0044 16.4 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 CRJ82115.1 - 0.0008 18.7 0.8 0.0071 15.6 0.3 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CRJ82115.1 - 0.00086 19.8 0.1 0.18 12.4 0.0 3.4 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CRJ82115.1 - 0.0014 17.9 0.0 0.0027 17.0 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 CRJ82115.1 - 0.005 16.0 0.1 0.026 13.6 0.1 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 CRJ82115.1 - 0.0083 15.4 0.0 0.045 13.0 0.0 2.0 2 0 0 2 2 2 1 Thi4 family Trp_halogenase PF04820.14 CRJ82115.1 - 0.011 14.6 0.1 0.061 12.2 0.1 2.0 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_9 PF13454.6 CRJ82115.1 - 0.092 12.7 0.6 0.36 10.8 0.2 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Glyco_hydro_71 PF03659.14 CRJ82124.1 - 1.9e-24 86.2 5.5 2.1e-24 86.1 5.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Abhydrolase_3 PF07859.13 CRJ82127.1 - 2.1e-53 181.3 0.0 2.6e-53 181.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 CRJ82127.1 - 6.5e-06 25.3 0.0 1.4e-05 24.2 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 CRJ82127.1 - 7e-05 22.4 0.0 0.0028 17.2 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 CRJ82127.1 - 0.0023 16.8 0.0 0.0032 16.4 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 CRJ82127.1 - 0.0047 16.2 0.0 0.0073 15.6 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 CRJ82127.1 - 0.031 14.1 0.0 0.079 12.8 0.0 1.6 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 CRJ82127.1 - 0.054 14.1 4.0 0.083 13.5 4.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family AXE1 PF05448.12 CRJ82127.1 - 0.058 12.1 0.0 0.17 10.5 0.0 1.7 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) WSC PF01822.19 CRJ82132.1 - 1.3e-140 457.9 141.5 3.7e-19 68.7 8.9 10.0 9 0 0 9 9 9 9 WSC domain PQQ_3 PF13570.6 CRJ82132.1 - 1.1e-08 35.2 19.6 0.013 15.9 0.1 8.2 9 0 0 9 9 9 3 PQQ-like domain Prok-RING_1 PF14446.6 CRJ82132.1 - 2.6e-05 24.0 4.1 0.18 11.7 0.2 3.3 2 0 0 2 2 2 2 Prokaryotic RING finger family 1 Peptidase_C53 PF05550.11 CRJ82132.1 - 0.0079 15.9 0.0 6.1 6.5 0.0 2.5 2 0 0 2 2 2 2 Pestivirus Npro endopeptidase C53 T3SS_ATPase_C PF18269.1 CRJ82132.1 - 0.026 14.4 0.2 10 6.0 0.0 2.3 2 0 0 2 2 2 0 T3SS EscN ATPase C-terminal domain PQQ PF01011.21 CRJ82132.1 - 0.037 14.0 17.5 25 5.0 0.0 7.5 6 0 0 6 6 6 0 PQQ enzyme repeat Amidase PF01425.21 CRJ82135.1 - 6.6e-06 25.3 0.0 7.6e-06 25.1 0.0 1.0 1 0 0 1 1 1 1 Amidase Amidase PF01425.21 CRJ82141.1 - 1.1e-75 255.3 0.1 6.1e-75 252.9 0.1 2.1 1 1 0 1 1 1 1 Amidase Fungal_trans_2 PF11951.8 CRJ82146.1 - 4.4e-08 32.3 0.1 5.5e-05 22.1 0.0 2.2 1 1 1 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 CRJ82146.1 - 1.2e-05 25.4 6.4 3.2e-05 24.0 6.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 CRJ82150.1 - 5.1e-30 104.6 25.4 5.1e-30 104.6 25.4 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Amidase PF01425.21 CRJ82156.1 - 1.5e-79 268.1 0.0 3.3e-79 266.9 0.0 1.6 2 0 0 2 2 2 1 Amidase MFS_1 PF07690.16 CRJ82161.1 - 1.8e-35 122.6 29.0 1.8e-35 122.6 29.0 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Phage_holin_2_1 PF04971.12 CRJ82161.1 - 0.07 13.1 2.4 0.37 10.8 0.0 2.9 2 0 0 2 2 2 0 Bacteriophage P21 holin S FAD_binding_4 PF01565.23 CRJ82171.1 - 1.7e-17 63.5 4.4 2.9e-17 62.7 4.4 1.4 1 0 0 1 1 1 1 FAD binding domain Lipocalin_9 PF17186.4 CRJ82176.1 - 0.16 12.3 0.5 0.37 11.1 0.5 1.6 1 0 0 1 1 1 0 Lipocalin-like domain DUF4271 PF14093.6 CRJ82181.1 - 0.055 13.4 6.5 0.077 12.9 6.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4271) Peptidase_C2 PF00648.21 CRJ82238.1 - 5.1e-20 71.7 0.1 3.3e-18 65.7 0.1 2.0 1 1 0 1 1 1 1 Calpain family cysteine protease Helicase_C PF00271.31 CRJ82289.1 - 2.8e-05 24.4 0.0 3.6e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF5639 PF18690.1 CRJ82289.1 - 0.16 12.2 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5639) MTS PF05175.14 CRJ82335.1 - 0.003 17.1 0.0 0.0039 16.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Ribosomal_L17 PF01196.19 CRJ82364.1 - 8.5e-13 49.0 0.0 1.3e-12 48.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L17 Aldedh PF00171.22 CRJ82364.1 - 0.072 11.6 0.0 0.1 11.1 0.0 1.1 1 0 0 1 1 1 0 Aldehyde dehydrogenase family Ribosomal_L19 PF01245.20 CRJ82417.1 - 3.9e-10 39.7 0.0 5.2e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L19 RRM_Rrp7 PF17799.1 CRJ82523.1 - 2.5e-06 27.4 0.0 2.7e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Rrp7 RRM-like N-terminal domain Pyr_redox PF00070.27 CRJ82623.1 - 0.022 15.3 0.0 0.036 14.6 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CRJ82623.1 - 0.074 12.6 0.0 0.074 12.6 0.0 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase Ribonuc_L-PSP PF01042.21 CRJ82697.1 - 2.6e-13 50.0 0.0 3.7e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF5529 PF17669.1 CRJ82700.1 - 0.032 14.3 0.1 0.033 14.2 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5529) Glyco_transf_64 PF09258.10 CRJ82706.1 - 2e-49 168.1 0.0 2.6e-49 167.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain DUF1768 PF08719.11 CRJ82710.1 - 1.8e-51 174.6 0.0 2.2e-51 174.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Amidase PF01425.21 CRJ82718.1 - 4.3e-71 240.2 0.3 3.4e-69 234.0 0.0 2.1 2 0 0 2 2 2 2 Amidase PNP_UDP_1 PF01048.20 CRJ82726.1 - 0.037 13.3 0.6 0.089 12.0 0.0 2.1 2 1 0 2 2 2 0 Phosphorylase superfamily TPR_12 PF13424.6 CRJ82730.1 - 1.8e-24 85.8 8.6 1.3e-07 31.8 1.3 5.0 2 2 3 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.6 CRJ82730.1 - 3e-19 68.2 9.6 0.00069 19.4 0.0 5.9 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_1 PF00515.28 CRJ82730.1 - 2.3e-09 36.7 6.4 0.3 11.0 0.1 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 CRJ82730.1 - 4.8e-09 35.7 0.8 1.4 9.3 0.0 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 CRJ82730.1 - 4.3e-07 29.5 11.0 0.038 14.1 0.2 5.7 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 CRJ82730.1 - 4.5e-07 29.4 0.7 0.095 12.8 0.0 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat NB-ARC PF00931.22 CRJ82730.1 - 4.9e-07 29.2 0.0 1.2e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain TPR_14 PF13428.6 CRJ82730.1 - 2.6e-06 27.8 4.3 9.8 7.3 0.1 6.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 CRJ82730.1 - 9e-06 25.3 1.5 0.0096 15.3 0.3 2.4 2 0 0 2 2 2 2 MalT-like TPR region AAA_25 PF13481.6 CRJ82730.1 - 0.006 16.2 0.0 0.014 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain TPR_4 PF07721.14 CRJ82730.1 - 0.0066 17.0 9.7 14 6.6 0.0 5.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 CRJ82730.1 - 0.84 10.3 13.4 14 6.5 2.8 5.1 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 CRJ82730.1 - 6.4 7.4 8.2 99 3.6 0.2 4.5 3 1 2 5 5 5 0 Tetratricopeptide repeat GPHR_N PF12537.8 CRJ82733.1 - 1e-22 80.0 0.0 1.9e-22 79.1 0.0 1.4 1 0 0 1 1 1 1 The Golgi pH Regulator (GPHR) Family N-terminal Usp PF00582.26 CRJ82733.1 - 0.00013 22.5 0.1 0.00013 22.5 0.1 3.0 3 0 0 3 3 3 1 Universal stress protein family ABA_GPCR PF12430.8 CRJ82733.1 - 0.00014 21.7 0.1 0.00028 20.7 0.1 1.5 1 0 0 1 1 1 1 Abscisic acid G-protein coupled receptor GTP_EFTU_D2 PF03144.25 CRJ82739.1 - 3.1e-09 37.1 0.0 9.7e-09 35.5 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 CRJ82739.1 - 1.9e-07 31.1 0.0 3.5e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU PF00009.27 CRJ82745.1 - 2.3e-57 193.7 0.0 3.1e-57 193.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CRJ82745.1 - 0.016 15.3 0.0 0.05 13.7 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase RRM_1 PF00076.22 CRJ82754.1 - 4.9e-06 26.3 0.0 8.1e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GTP_EFTU PF00009.27 CRJ82759.1 - 1.1e-32 113.1 0.0 2.2e-32 112.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 CRJ82759.1 - 7.7e-15 54.7 0.0 1.6e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus RRM_1 PF00076.22 CRJ82759.1 - 6.1e-13 48.4 0.1 1.4e-12 47.2 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GTP_EFTU_D2 PF03144.25 CRJ82759.1 - 6.8e-10 39.2 0.0 1.9e-09 37.8 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 CRJ82759.1 - 1.5e-06 28.2 0.0 3e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 CRJ82759.1 - 4.8e-05 23.1 0.0 0.00031 20.5 0.0 2.3 2 0 0 2 2 2 1 Elongation factor G, domain IV Fmp27 PF10344.9 CRJ82764.1 - 1.4e-166 556.2 2.4 9.8e-85 285.3 0.2 2.0 2 0 0 2 2 2 2 Mitochondrial protein from FMP27 Ntox44 PF15607.6 CRJ82764.1 - 0.0026 18.0 0.0 4.3 7.7 0.0 2.4 2 0 0 2 2 2 2 Bacterial toxin 44 DUF3583 PF12126.8 CRJ82764.1 - 0.011 15.2 0.0 4.6 6.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3583) DUF5402 PF17393.2 CRJ82764.1 - 0.052 13.5 1.2 12 5.8 0.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5402) HMMR_C PF15908.5 CRJ82764.1 - 0.19 12.0 1.6 21 5.4 0.1 2.4 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor C-terminal Fmp27_WPPW PF10359.9 CRJ82769.1 - 0 1185.9 18.0 2.4e-180 600.6 1.2 3.1 4 0 0 4 4 4 2 RNA pol II promoter Fmp27 protein domain Apt1 PF10351.9 CRJ82769.1 - 2.9e-268 890.4 10.5 1.8e-173 577.8 0.8 3.3 4 0 0 4 4 2 2 Golgi-body localisation protein domain Fmp27 PF10344.9 CRJ82769.1 - 8e-141 470.9 0.0 6e-112 375.4 0.0 3.3 2 1 0 2 2 2 2 Mitochondrial protein from FMP27 Fmp27_GFWDK PF10347.9 CRJ82769.1 - 1.4e-111 369.6 0.0 1.4e-54 184.5 0.0 2.5 2 0 0 2 2 2 2 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 CRJ82769.1 - 1.5e-111 369.2 1.7 1.6e-54 184.0 0.1 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 CRJ82769.1 - 6.7e-70 232.3 0.0 1.9e-33 115.2 0.0 2.9 2 0 0 2 2 2 2 RNA pol II promoter Fmp27 protein domain Serine_rich PF08824.10 CRJ82769.1 - 1.6e-05 25.0 3.3 0.14 12.1 0.2 3.0 2 0 0 2 2 2 2 Serine rich protein interaction domain CheZ PF04344.13 CRJ82769.1 - 4e-05 23.6 0.0 0.53 10.2 0.0 2.8 2 0 0 2 2 2 2 Chemotaxis phosphatase, CheZ PspB PF06667.12 CRJ82769.1 - 0.015 15.3 1.5 9.4 6.4 0.1 3.2 2 0 0 2 2 2 0 Phage shock protein B TAF PF02969.17 CRJ82769.1 - 0.031 14.5 0.4 16 5.8 0.0 2.8 2 0 0 2 2 2 0 TATA box binding protein associated factor (TAF) TerB_C PF15615.6 CRJ82769.1 - 0.094 13.0 0.9 26 5.1 0.1 3.1 2 0 0 2 2 2 0 TerB-C domain DUF4298 PF14131.6 CRJ82769.1 - 0.15 12.0 4.0 11 6.0 0.3 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) Antimicrobial10 PF08105.11 CRJ82769.1 - 0.22 11.6 0.7 39 4.4 0.1 2.7 2 0 0 2 2 2 0 Metchnikowin family JAB PF01398.21 CRJ82777.1 - 2.6e-30 104.8 0.5 7.2e-30 103.4 0.1 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 CRJ82777.1 - 1.9e-24 86.4 0.1 4.4e-24 85.2 0.1 1.7 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 CRJ82777.1 - 2.7e-05 23.9 0.0 0.00011 22.0 0.0 2.0 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain GGACT PF06094.12 CRJ82781.1 - 8.9e-12 45.7 0.0 1e-11 45.5 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like ChaC PF04752.12 CRJ82781.1 - 0.032 14.3 0.0 0.043 13.9 0.0 1.2 1 0 0 1 1 1 0 ChaC-like protein MFS_1 PF07690.16 CRJ82785.1 - 1.1e-30 106.8 29.3 1.1e-30 106.8 29.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3328 PF11807.8 CRJ82790.1 - 5e-48 163.8 1.0 6.5e-48 163.4 1.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) PSI_8 PF00796.18 CRJ82795.1 - 2.4 8.1 4.5 4.3 7.3 4.5 1.3 1 0 0 1 1 1 0 Photosystem I reaction centre subunit VIII His_Phos_2 PF00328.22 CRJ82801.1 - 0.061 12.7 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) Caps_synth PF05704.12 CRJ82801.1 - 0.12 11.7 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein DUF1939 PF09154.10 CRJ82813.1 - 0.0046 17.1 0.0 0.014 15.6 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1939) Dynamin_N PF00350.23 CRJ82817.1 - 3e-35 121.7 0.1 9.4e-35 120.1 0.0 1.9 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.20 CRJ82817.1 - 2.5e-25 89.3 0.0 1.2e-19 70.6 0.0 2.3 2 0 0 2 2 2 2 Dynamin central region GED PF02212.18 CRJ82817.1 - 0.00031 20.8 1.0 0.00083 19.5 0.1 2.2 2 0 0 2 2 2 1 Dynamin GTPase effector domain YcaO PF02624.16 CRJ82817.1 - 0.001 18.4 0.1 0.0019 17.5 0.1 1.3 1 0 0 1 1 1 1 YcaO cyclodehydratase, ATP-ad Mg2+-binding MMR_HSR1 PF01926.23 CRJ82817.1 - 0.0015 18.6 0.3 0.02 15.0 0.3 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 CRJ82817.1 - 0.011 16.2 0.5 0.25 11.7 0.0 2.8 2 0 0 2 2 2 0 AAA ATPase domain AIG1 PF04548.16 CRJ82817.1 - 0.066 12.5 0.8 4 6.7 0.4 2.5 2 0 0 2 2 2 0 AIG1 family AAA_21 PF13304.6 CRJ82817.1 - 0.079 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system MAP65_ASE1 PF03999.12 CRJ82822.1 - 4.3e-64 217.3 4.6 1.2e-63 215.8 0.0 2.1 2 0 0 2 2 2 1 Microtubule associated protein (MAP65/ASE1 family) Abhydrolase_1 PF00561.20 CRJ82822.1 - 2.9e-44 151.6 0.1 4.7e-24 85.4 0.0 2.6 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CRJ82822.1 - 0.0007 20.3 10.7 0.033 14.8 1.0 2.8 1 1 1 2 2 2 2 Alpha/beta hydrolase family Say1_Mug180 PF10340.9 CRJ82822.1 - 0.11 11.4 0.0 5.3 5.8 0.0 2.1 2 0 0 2 2 2 0 Steryl acetyl hydrolase Rx_N PF18052.1 CRJ82822.1 - 1.2 9.4 4.5 0.5 10.7 0.7 2.3 2 0 0 2 2 2 0 Rx N-terminal domain Peptidase_M28 PF04389.17 CRJ82826.1 - 5.8e-27 94.7 0.4 2.3e-26 92.7 0.4 1.8 1 1 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 CRJ82826.1 - 1.3e-06 28.2 0.0 1.9e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 CRJ82826.1 - 7.4e-05 21.9 0.1 0.00012 21.2 0.1 1.3 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase DUF4910 PF16254.5 CRJ82826.1 - 0.17 10.7 0.0 0.27 10.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4910) AAA PF00004.29 CRJ82829.1 - 1e-15 58.3 0.0 2.2e-15 57.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CRJ82829.1 - 0.00069 20.0 0.9 0.0022 18.4 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CRJ82829.1 - 0.0058 16.9 3.3 0.068 13.4 0.3 3.2 2 1 1 3 3 3 1 AAA domain ATPase PF06745.13 CRJ82829.1 - 0.024 14.0 0.1 0.054 12.8 0.1 1.6 1 0 0 1 1 1 0 KaiC AAA_30 PF13604.6 CRJ82829.1 - 0.037 13.7 0.0 0.079 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 CRJ82829.1 - 0.052 13.5 0.0 0.21 11.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 CRJ82829.1 - 0.18 11.5 0.0 0.36 10.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF445 PF04286.12 CRJ82835.1 - 0.011 15.5 3.1 0.017 15.0 0.2 2.4 3 1 1 4 4 4 0 Protein of unknown function (DUF445) DUF4449 PF14613.6 CRJ82835.1 - 0.066 13.3 0.0 0.066 13.3 0.0 2.6 4 0 0 4 4 4 0 Protein of unknown function (DUF4449) Ku_PK_bind PF08785.11 CRJ82835.1 - 0.11 12.7 0.0 0.37 11.0 0.0 1.9 1 0 0 1 1 1 0 Ku C terminal domain like RsbRD_N PF14361.6 CRJ82835.1 - 0.32 11.7 3.6 1.3 9.7 0.8 3.1 2 1 1 3 3 3 0 RsbT co-antagonist protein rsbRD N-terminal domain GED PF02212.18 CRJ82838.1 - 0.00034 20.7 0.1 0.0018 18.4 0.1 2.3 1 0 0 1 1 1 1 Dynamin GTPase effector domain DUF445 PF04286.12 CRJ82838.1 - 0.013 15.3 2.9 0.077 12.8 2.9 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF445) RsbRD_N PF14361.6 CRJ82838.1 - 0.035 14.8 2.9 1.3 9.7 0.8 3.8 2 1 1 3 3 3 0 RsbT co-antagonist protein rsbRD N-terminal domain Ku_PK_bind PF08785.11 CRJ82838.1 - 0.081 13.1 0.0 0.41 10.8 0.0 2.2 1 0 0 1 1 1 0 Ku C terminal domain like THOC2_N PF16134.5 CRJ82842.1 - 4.7e-189 630.1 0.0 8.3e-189 629.3 0.0 1.3 1 0 0 1 1 1 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 CRJ82842.1 - 2.1e-84 283.3 0.2 3.3e-84 282.6 0.2 1.3 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 LprI PF07007.12 CRJ82842.1 - 0.29 11.8 2.1 1.5 9.5 2.1 2.2 1 0 0 1 1 1 0 Lysozyme inhibitor LprI WSC PF01822.19 CRJ82851.1 - 1.9e-10 40.8 8.7 1.9e-10 40.8 8.7 1.8 2 0 0 2 2 2 1 WSC domain Adeno_E3_CR2 PF02439.15 CRJ82851.1 - 8.1e-05 22.3 0.1 0.00014 21.5 0.1 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Podoplanin PF05808.11 CRJ82851.1 - 0.00025 21.2 1.2 0.00057 20.0 1.2 1.6 1 0 0 1 1 1 1 Podoplanin SKG6 PF08693.10 CRJ82851.1 - 0.0027 17.1 3.7 0.0064 15.9 3.7 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain CcmD PF04995.14 CRJ82851.1 - 0.0053 16.8 0.3 0.013 15.6 0.3 1.7 1 0 0 1 1 1 1 Heme exporter protein D (CcmD) Mid2 PF04478.12 CRJ82851.1 - 0.012 15.4 0.4 0.027 14.3 0.2 1.7 1 1 0 1 1 1 0 Mid2 like cell wall stress sensor Gram_pos_anchor PF00746.21 CRJ82851.1 - 0.015 15.3 0.1 0.015 15.3 0.1 1.7 2 0 0 2 2 1 0 LPXTG cell wall anchor motif TMEM154 PF15102.6 CRJ82851.1 - 0.019 14.8 0.1 0.052 13.4 0.1 1.7 1 1 0 1 1 1 0 TMEM154 protein family EphA2_TM PF14575.6 CRJ82851.1 - 0.028 15.3 0.0 0.063 14.2 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 CRJ82851.1 - 0.034 14.1 0.0 0.059 13.3 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain PTP_tm PF18861.1 CRJ82851.1 - 0.039 14.0 0.1 0.062 13.3 0.1 1.3 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Phage_holin_2_1 PF04971.12 CRJ82851.1 - 0.088 12.8 0.1 0.33 11.0 0.0 2.0 2 0 0 2 2 2 0 Bacteriophage P21 holin S DUF2755 PF10954.8 CRJ82851.1 - 0.1 12.5 0.1 0.19 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2755) DUF2207 PF09972.9 CRJ82851.1 - 0.1 11.4 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Glycophorin_A PF01102.18 CRJ82851.1 - 0.14 12.4 1.7 0.62 10.3 1.6 2.1 1 1 0 1 1 1 0 Glycophorin A Phage_holin_2_4 PF16082.5 CRJ82851.1 - 0.15 11.8 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like Tad_C PF09977.9 CRJ82854.1 - 0.09 14.0 0.3 2 9.7 0.0 2.2 2 0 0 2 2 2 0 Putative Tad-like Flp pilus-assembly GMC_oxred_C PF05199.13 CRJ82857.1 - 2.6e-31 109.1 0.0 4.6e-31 108.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 CRJ82857.1 - 1.9e-27 96.4 0.0 1.2e-19 70.8 0.0 3.3 3 0 0 3 3 3 3 GMC oxidoreductase Pyr_redox_2 PF07992.14 CRJ82857.1 - 0.00043 19.6 0.0 0.0012 18.2 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CRJ82857.1 - 0.00065 19.9 0.0 0.0018 18.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CRJ82857.1 - 0.0076 15.4 0.3 0.015 14.4 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 CRJ82857.1 - 0.024 13.7 0.0 0.037 13.1 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 CRJ82857.1 - 0.025 13.9 0.3 0.04 13.1 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain Fimbrial PF00419.20 CRJ82857.1 - 0.053 13.8 0.0 0.099 12.9 0.0 1.5 1 0 0 1 1 1 0 Fimbrial protein Pyr_redox_3 PF13738.6 CRJ82857.1 - 0.11 11.7 0.4 9.3 5.4 0.1 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CRJ82857.1 - 0.16 10.6 0.1 0.27 9.9 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein HHH PF00633.23 CRJ82857.1 - 2.5 8.1 5.1 1.3 9.0 0.1 3.0 4 0 0 4 4 4 0 Helix-hairpin-helix motif 4HBT_2 PF13279.6 CRJ82860.1 - 6.2e-21 75.2 0.0 1.4e-20 74.0 0.0 1.5 1 1 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 CRJ82860.1 - 0.01 16.2 0.0 0.019 15.3 0.0 1.4 1 0 0 1 1 1 0 Thioesterase superfamily Bac_rhamnosid6H PF17389.2 CRJ82862.1 - 5.8e-92 308.5 5.2 6.7e-62 209.7 3.4 2.3 1 1 1 2 2 2 2 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 CRJ82862.1 - 2.5e-55 187.0 0.0 4e-55 186.3 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid PF05592.11 CRJ82862.1 - 2.2e-26 91.8 0.0 4.2e-26 90.9 0.0 1.5 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Bac_rhamnosid_C PF17390.2 CRJ82862.1 - 1.5e-15 56.7 0.0 4.6e-15 55.2 0.0 1.8 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain DLL_N PF12413.8 CRJ82865.1 - 0.014 16.6 0.2 0.016 16.5 0.2 1.2 1 0 0 1 1 1 0 Homeobox protein distal-less-like N terminal Mid2 PF04478.12 CRJ82872.1 - 0.025 14.4 0.0 0.061 13.2 0.0 1.6 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor SKG6 PF08693.10 CRJ82872.1 - 0.037 13.4 0.0 0.092 12.2 0.0 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF347 PF03988.12 CRJ82872.1 - 0.085 13.1 0.5 0.17 12.1 0.0 1.7 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) Vpu PF00558.19 CRJ82872.1 - 0.17 11.6 0.1 0.53 10.1 0.0 1.7 2 0 0 2 2 2 0 Vpu protein GAS PF13851.6 CRJ82876.1 - 0.042 13.2 7.6 0.087 12.2 7.6 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding BRE1 PF08647.11 CRJ82876.1 - 5.5 7.1 10.7 17 5.6 3.9 2.6 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase YabA PF06156.13 CRJ82876.1 - 7.2 7.3 8.5 15 6.3 2.2 2.5 1 1 1 2 2 2 0 Initiation control protein YabA RSN1_7TM PF02714.15 CRJ82880.1 - 6e-85 284.9 23.4 6e-85 284.9 23.4 2.6 3 0 0 3 3 3 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 CRJ82880.1 - 3.7e-44 150.2 1.4 3.7e-44 150.2 1.4 2.7 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 CRJ82880.1 - 9.8e-37 126.9 0.0 1.4e-36 126.4 0.0 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 CRJ82880.1 - 3e-32 110.6 0.1 6.7e-32 109.5 0.1 1.6 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter kleA_kleC PF17383.2 CRJ82880.1 - 0.017 15.4 1.1 0.36 11.2 0.1 3.0 3 0 0 3 3 3 0 Uncharacterized KorC regulated protein A COesterase PF00135.28 CRJ82891.1 - 9.5e-82 275.5 0.0 1.3e-81 275.0 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CRJ82891.1 - 2.8e-06 27.4 0.2 1.7e-05 24.8 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold LSM PF01423.22 CRJ82894.1 - 1.9e-14 53.1 0.0 3.3e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 LSM domain PPR_2 PF13041.6 CRJ82894.1 - 7.6e-06 26.0 0.0 0.28 11.4 0.0 5.1 6 0 0 6 6 6 2 PPR repeat family PPR PF01535.20 CRJ82894.1 - 0.00016 21.7 0.3 0.21 11.9 0.0 5.0 6 0 0 6 6 6 1 PPR repeat PPR_long PF17177.4 CRJ82894.1 - 0.0039 16.6 0.2 0.042 13.2 0.2 2.5 3 0 0 3 3 3 1 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 CRJ82894.1 - 0.054 13.2 2.2 0.33 10.7 0.0 3.2 3 0 0 3 3 3 0 PPR repeat PPR_3 PF13812.6 CRJ82894.1 - 0.059 13.5 0.0 5.7 7.1 0.0 3.6 4 0 0 4 4 4 0 Pentatricopeptide repeat domain TPR_2 PF07719.17 CRJ82894.1 - 0.46 10.7 1.8 1.5 9.1 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat hDGE_amylase PF14701.6 CRJ82990.1 - 6.3e-48 164.0 0.0 6.8e-48 163.8 0.0 1.0 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GATase_2 PF00310.21 CRJ83051.1 - 3.3e-75 253.4 0.0 4.5e-75 253.0 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Pyr_redox_2 PF07992.14 CRJ83051.1 - 5.7e-08 32.3 0.0 1.1e-06 28.1 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CRJ83051.1 - 0.061 12.6 0.0 3.7 6.7 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HAUS-augmin3 PF14932.6 CRJ83183.1 - 0.84 9.2 5.1 0.12 11.9 1.0 1.6 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 DUF2457 PF10446.9 CRJ83183.1 - 1.3 8.0 6.7 1.8 7.6 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TFIIA PF03153.13 CRJ83183.1 - 2.7 7.9 16.1 3.5 7.5 16.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cpn60_TCP1 PF00118.24 CRJ83250.1 - 5.9e-45 153.8 0.0 6.4e-45 153.7 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Herpes_UL6 PF01763.16 CRJ83250.1 - 0.014 13.9 0.0 0.015 13.9 0.0 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like VHS PF00790.19 CRJ83336.1 - 4e-46 156.4 0.0 5.4e-46 155.9 0.0 1.2 1 0 0 1 1 1 1 VHS domain DUF1651 PF07864.11 CRJ83336.1 - 0.13 12.6 0.1 0.32 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1651) GTP_EFTU PF00009.27 CRJ83445.1 - 3.7e-22 78.8 0.0 4.9e-22 78.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Mito_carr PF00153.27 CRJ83445.1 - 4.7e-15 55.3 0.1 1.1e-14 54.1 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial carrier protein GTP_EFTU_D3 PF03143.17 CRJ83445.1 - 5.3e-13 49.3 0.0 1.3e-12 48.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CRJ83445.1 - 3.4e-08 33.8 0.4 7e-08 32.8 0.4 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Peptidase_M43 PF05572.13 CRJ83507.1 - 8.7e-08 32.2 0.4 2.3e-07 30.9 0.0 1.9 2 0 0 2 2 2 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 CRJ83507.1 - 0.014 15.6 0.1 0.062 13.4 0.1 2.0 1 1 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_M10 PF00413.24 CRJ83507.1 - 0.02 14.7 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 Matrixin Reprolysin_3 PF13582.6 CRJ83507.1 - 0.21 12.1 0.3 1.1 9.8 0.3 2.2 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DAO PF01266.24 CRJ83517.1 - 3e-68 231.0 2.8 3.8e-68 230.7 2.8 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CRJ83517.1 - 6e-06 25.7 0.0 0.0035 16.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CRJ83517.1 - 2.3e-05 24.9 0.0 0.29 11.7 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CRJ83517.1 - 3.8e-05 23.8 0.4 9.8e-05 22.5 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 CRJ83517.1 - 0.00086 18.3 0.2 0.0014 17.5 0.2 1.3 1 0 0 1 1 1 1 Tryptophan halogenase FAD_binding_2 PF00890.24 CRJ83517.1 - 0.0013 18.0 1.9 0.0047 16.1 1.9 1.8 1 1 0 1 1 1 1 FAD binding domain Mqo PF06039.15 CRJ83517.1 - 0.0031 16.1 0.0 1.3 7.5 0.0 2.1 2 0 0 2 2 2 2 Malate:quinone oxidoreductase (Mqo) Thi4 PF01946.17 CRJ83517.1 - 0.0061 15.8 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Thi4 family MCRA PF06100.11 CRJ83517.1 - 0.021 13.7 0.6 0.27 10.0 0.2 2.0 2 0 0 2 2 2 0 MCRA family Sacchrp_dh_NADP PF03435.18 CRJ83517.1 - 0.042 14.1 0.1 0.18 12.1 0.1 2.1 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain DHDPS PF00701.22 CRJ83521.1 - 1.6e-30 105.8 0.0 1.9e-30 105.6 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family GFO_IDH_MocA PF01408.22 CRJ83525.1 - 5.8e-11 43.3 0.8 2.5e-10 41.2 0.8 2.1 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold CoA_binding_2 PF13380.6 CRJ83525.1 - 0.039 14.5 0.0 0.083 13.4 0.0 1.5 1 0 0 1 1 1 0 CoA binding domain IglC PF11550.8 CRJ83525.1 - 0.048 13.1 0.1 0.096 12.1 0.1 1.4 1 0 0 1 1 1 0 Intracellular growth locus C protein NAD_binding_3 PF03447.16 CRJ83525.1 - 0.053 14.2 0.0 0.1 13.3 0.0 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain LigB PF02900.18 CRJ83525.1 - 0.054 12.6 0.1 0.1 11.7 0.1 1.4 1 0 0 1 1 1 0 Catalytic LigB subunit of aromatic ring-opening dioxygenase Cellulase PF00150.18 CRJ83525.1 - 0.062 12.7 0.1 0.1 12.0 0.1 1.4 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Nop16 PF09420.10 CRJ83529.1 - 7.9e-21 75.1 6.2 1.3e-20 74.4 6.2 1.3 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 GFO_IDH_MocA PF01408.22 CRJ83529.1 - 1.1e-10 42.4 0.0 2.2e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold CoA_binding_2 PF13380.6 CRJ83529.1 - 0.042 14.4 0.0 0.1 13.1 0.0 1.6 1 0 0 1 1 1 0 CoA binding domain IglC PF11550.8 CRJ83529.1 - 0.057 12.9 0.1 0.11 11.9 0.1 1.4 1 0 0 1 1 1 0 Intracellular growth locus C protein NAD_binding_3 PF03447.16 CRJ83529.1 - 0.06 14.0 0.0 0.13 13.0 0.0 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Cellulase PF00150.18 CRJ83529.1 - 0.073 12.5 0.1 0.13 11.6 0.1 1.4 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) LigB PF02900.18 CRJ83529.1 - 0.079 12.0 0.1 0.13 11.4 0.1 1.2 1 0 0 1 1 1 0 Catalytic LigB subunit of aromatic ring-opening dioxygenase Nop16 PF09420.10 CRJ83534.1 - 4.1e-69 232.8 10.0 4.7e-69 232.6 10.0 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 ABC_tran_Xtn PF12848.7 CRJ83534.1 - 1.5 8.9 13.1 0.11 12.6 5.8 2.2 2 0 0 2 2 2 0 ABC transporter MARVEL PF01284.23 CRJ83537.1 - 0.00036 20.6 0.6 0.00056 20.0 0.6 1.2 1 0 0 1 1 1 1 Membrane-associating domain Rit1_C PF17184.4 CRJ83542.1 - 2.7e-147 489.4 0.0 2.2e-106 355.3 0.0 3.3 3 0 0 3 3 3 3 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 CRJ83542.1 - 3.3e-48 162.6 0.0 5.2e-35 120.1 0.0 2.9 2 0 0 2 2 2 2 Rit1 DUSP-like domain DUF3830 PF12903.7 CRJ83542.1 - 0.021 14.5 0.3 25 4.5 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3830) FTZ PF03867.14 CRJ83542.1 - 0.11 12.1 0.6 0.47 9.9 0.0 2.0 2 0 0 2 2 2 0 Fushi tarazu (FTZ), N-terminal region UDPG_MGDP_dh_C PF03720.15 CRJ83547.1 - 0.11 12.9 0.0 0.11 12.9 0.0 1.3 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain HGTP_anticodon2 PF12745.7 CRJ83552.1 - 1.9e-73 247.2 9.2 1.9e-73 247.2 9.2 2.2 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase PF00069.25 CRJ83552.1 - 4.8e-66 222.8 0.0 4.4e-34 118.0 0.0 4.7 4 0 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.17 CRJ83552.1 - 2.3e-40 138.5 0.0 2.6e-18 66.3 0.0 3.5 3 0 0 3 3 3 3 Protein tyrosine kinase UQ_con PF00179.26 CRJ83552.1 - 1.2e-32 112.5 0.1 4.9e-32 110.5 0.1 2.1 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme tRNA-synt_His PF13393.6 CRJ83552.1 - 3.3e-19 69.3 0.0 3.3e-19 69.3 0.0 2.5 3 0 0 3 3 3 1 Histidyl-tRNA synthetase RWD PF05773.22 CRJ83552.1 - 7.6e-15 55.2 0.3 5e-11 42.9 0.0 3.3 3 0 0 3 3 3 2 RWD domain APH PF01636.23 CRJ83552.1 - 1.3e-06 28.5 4.5 0.019 14.9 0.0 3.6 3 1 0 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.6 CRJ83552.1 - 0.00022 20.7 0.0 0.013 14.9 0.0 2.5 2 0 0 2 2 2 1 Kinase-like YrbL-PhoP_reg PF10707.9 CRJ83552.1 - 0.016 14.8 0.0 1.2 8.6 0.0 2.6 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Pkinase_fungal PF17667.1 CRJ83552.1 - 0.092 11.5 8.9 0.97 8.1 0.0 3.2 2 1 0 2 2 2 0 Fungal protein kinase Cut12 PF11500.8 CRJ83558.1 - 5.3e-48 162.6 14.4 5.3e-48 162.6 14.4 3.3 2 1 1 3 3 3 1 Spindle pole body formation-associated protein Fez1 PF06818.15 CRJ83558.1 - 0.002 18.6 46.8 0.053 14.0 21.5 3.3 1 1 2 3 3 3 3 Fez1 DUF3138 PF11336.8 CRJ83558.1 - 0.78 8.3 4.0 1.6 7.3 4.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF1640 PF07798.11 CRJ83558.1 - 1.4 8.9 25.9 0.71 9.9 3.2 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1640) ATG16 PF08614.11 CRJ83558.1 - 1.8 8.7 50.6 0.41 10.8 32.8 3.1 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) DUF1843 PF08898.10 CRJ83558.1 - 7.9 7.1 11.2 0.13 12.8 1.3 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) IGPD PF00475.18 CRJ83563.1 - 5.3e-60 201.9 0.3 7.5e-60 201.4 0.3 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase DER1 PF04511.15 CRJ83568.1 - 2.4e-22 79.8 5.8 2.8e-22 79.6 5.8 1.0 1 0 0 1 1 1 1 Der1-like family Jiraiya PF15038.6 CRJ83568.1 - 0.061 12.8 2.7 0.38 10.2 0.0 2.4 2 1 0 2 2 2 0 Jiraiya DUF2070 PF09843.9 CRJ83568.1 - 1 7.6 5.4 1.2 7.4 5.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) CN_hydrolase PF00795.22 CRJ83577.1 - 9e-16 58.0 0.0 1.2e-14 54.3 0.0 2.3 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase DKCLD PF08068.12 CRJ83585.1 - 5.1e-34 116.1 0.2 1.1e-32 111.8 0.2 2.5 2 0 0 2 2 2 1 DKCLD (NUC011) domain PUA PF01472.20 CRJ83585.1 - 3.1e-22 78.3 1.1 6.4e-22 77.3 1.1 1.6 1 0 0 1 1 1 1 PUA domain TruB_N PF01509.18 CRJ83585.1 - 5.5e-22 78.7 4.9 3.6e-20 72.9 0.3 3.6 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 CRJ83585.1 - 5.9e-22 77.6 1.0 1.1e-21 76.7 1.0 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain UPF0113 PF03657.13 CRJ83585.1 - 0.00032 20.9 0.0 0.00084 19.6 0.0 1.7 1 0 0 1 1 1 1 UPF0113 PUA domain Med19 PF10278.9 CRJ83585.1 - 6.5 6.6 12.4 14 5.5 12.4 1.5 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 p450 PF00067.22 CRJ83592.1 - 8.6e-48 163.2 0.0 1.3e-47 162.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans_2 PF11951.8 CRJ83597.1 - 1.4e-07 30.7 0.2 2.1e-06 26.8 0.0 2.5 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRJ83597.1 - 1.3e-06 28.4 9.2 1.3e-06 28.4 9.2 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LTV PF04180.14 CRJ83603.1 - 3e-124 415.6 11.2 3e-124 415.6 11.2 2.4 3 0 0 3 3 3 1 Low temperature viability protein SAC3_GANP PF03399.16 CRJ83603.1 - 3.3e-93 312.3 0.0 4.9e-93 311.7 0.0 1.3 1 0 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 CRJ83603.1 - 0.00057 19.9 0.0 0.0015 18.6 0.0 1.6 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family Rep_fac_C PF08542.11 CRJ83608.1 - 5.7e-21 74.7 0.0 1.3e-20 73.6 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain MMR_HSR1 PF01926.23 CRJ83608.1 - 3e-17 62.7 0.9 4.2e-15 55.8 0.1 3.4 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA PF00004.29 CRJ83608.1 - 9.6e-13 48.7 0.2 2.2e-10 41.1 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 CRJ83608.1 - 1.4e-11 44.4 0.0 9e-08 32.1 0.0 2.8 1 1 1 2 2 2 2 DNA polymerase III, delta subunit FeoB_N PF02421.18 CRJ83608.1 - 2.7e-08 33.5 0.3 1.7e-05 24.4 0.0 2.8 3 0 0 3 3 3 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CRJ83608.1 - 4.8e-08 33.1 0.0 0.0022 17.9 0.0 3.4 3 0 0 3 3 3 1 RsgA GTPase AAA_14 PF13173.6 CRJ83608.1 - 1.2e-06 28.5 0.1 5.9e-06 26.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CRJ83608.1 - 8.6e-06 26.1 0.2 0.37 11.1 0.0 3.9 2 2 2 4 4 4 1 AAA domain AAA_16 PF13191.6 CRJ83608.1 - 1.3e-05 25.7 9.3 0.00078 19.9 0.0 4.9 2 2 2 4 4 4 1 AAA ATPase domain MeaB PF03308.16 CRJ83608.1 - 2.6e-05 23.4 0.1 0.02 13.9 0.0 2.7 3 0 0 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB RuvB_N PF05496.12 CRJ83608.1 - 5e-05 23.1 0.3 0.00057 19.7 0.0 2.6 3 0 0 3 3 2 1 Holliday junction DNA helicase RuvB P-loop domain Viral_helicase1 PF01443.18 CRJ83608.1 - 0.00032 20.5 0.0 0.00062 19.6 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.11 CRJ83608.1 - 0.001 18.9 0.0 0.0024 17.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 CRJ83608.1 - 0.0035 17.9 0.3 3.7 8.1 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 CRJ83608.1 - 0.004 16.9 0.5 0.69 9.6 0.0 3.2 3 0 0 3 3 3 1 AAA domain Rad17 PF03215.15 CRJ83608.1 - 0.0049 16.8 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_24 PF13479.6 CRJ83608.1 - 0.006 16.3 0.0 0.41 10.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain DNA_pol3_delta PF06144.13 CRJ83608.1 - 0.0091 15.8 0.1 0.056 13.2 0.0 2.1 2 0 0 2 2 2 1 DNA polymerase III, delta subunit TniB PF05621.11 CRJ83608.1 - 0.011 15.2 0.1 6.7 6.1 0.0 3.2 3 0 0 3 3 3 0 Bacterial TniB protein RNA_helicase PF00910.22 CRJ83608.1 - 0.012 16.0 0.1 3.1 8.2 0.0 3.1 2 1 0 2 2 2 0 RNA helicase AAA_assoc_2 PF16193.5 CRJ83608.1 - 0.016 15.5 0.0 0.13 12.6 0.0 2.5 2 0 0 2 2 2 0 AAA C-terminal domain AIG1 PF04548.16 CRJ83608.1 - 0.017 14.5 0.1 0.036 13.4 0.1 1.6 1 0 0 1 1 1 0 AIG1 family Mg_chelatase PF01078.21 CRJ83608.1 - 0.019 14.3 0.1 0.1 11.9 0.0 2.1 1 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI KTI12 PF08433.10 CRJ83608.1 - 0.02 14.3 0.3 0.09 12.2 0.0 2.1 2 0 0 2 2 2 0 Chromatin associated protein KTI12 cobW PF02492.19 CRJ83608.1 - 0.025 14.2 0.9 6.5 6.3 0.0 2.8 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 CRJ83608.1 - 0.034 14.0 0.2 0.17 11.7 0.0 2.4 3 0 0 3 3 1 0 NTPase AAA_19 PF13245.6 CRJ83608.1 - 0.04 14.3 0.4 0.15 12.4 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_11 PF13086.6 CRJ83608.1 - 0.045 13.5 4.1 0.059 13.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 CRJ83608.1 - 0.053 14.0 0.4 12 6.4 0.0 2.8 2 0 0 2 2 2 0 ABC transporter Thymidylate_kin PF02223.17 CRJ83608.1 - 0.082 12.6 0.1 2.4 7.8 0.0 2.6 2 0 0 2 2 2 0 Thymidylate kinase FtsK_SpoIIIE PF01580.18 CRJ83608.1 - 0.1 12.0 0.0 2.3 7.5 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Dynamin_N PF00350.23 CRJ83608.1 - 0.13 12.4 0.1 0.13 12.4 0.1 3.0 3 0 0 3 3 2 0 Dynamin family DEAD PF00270.29 CRJ83608.1 - 0.13 12.0 0.1 2.8 7.7 0.0 2.3 1 1 1 2 2 2 0 DEAD/DEAH box helicase DUF5523 PF17661.1 CRJ83608.1 - 0.15 11.7 8.6 0.3 10.8 8.6 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5523) TRAP_alpha PF03896.16 CRJ83608.1 - 0.47 9.6 3.1 0.82 8.8 3.1 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit FYDLN_acid PF09538.10 CRJ83608.1 - 1.1 10.0 7.6 2.8 8.7 7.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Paf1 PF03985.13 CRJ83608.1 - 1.3 7.9 9.6 2.1 7.2 9.6 1.2 1 0 0 1 1 1 0 Paf1 ORC_WH_C PF18137.1 CRJ83608.1 - 1.7 8.7 5.8 4.2 7.4 5.8 1.6 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal DUF4746 PF15928.5 CRJ83608.1 - 2.2 7.7 10.4 4.2 6.7 10.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF3089 PF11288.8 CRJ83615.1 - 0.065 12.8 0.0 0.067 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) DUF3539 PF12058.8 CRJ83615.1 - 0.076 13.2 0.0 0.1 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3539) Bacteriocin_IIc PF10439.9 CRJ83615.1 - 0.86 9.8 6.2 0.81 9.8 4.4 1.7 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide UreF PF01730.16 CRJ83619.1 - 3.9e-21 76.0 1.8 7.6e-21 75.1 1.8 1.4 1 0 0 1 1 1 1 UreF Acyl-CoA_dh_2 PF08028.11 CRJ83619.1 - 0.03 14.6 0.3 0.076 13.3 0.3 1.6 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain DUF429 PF04250.13 CRJ83619.1 - 0.042 13.6 0.1 0.092 12.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF429) Phage_lysis PF03245.13 CRJ83619.1 - 0.048 13.8 0.1 0.048 13.8 0.1 2.3 2 1 0 2 2 2 0 Bacteriophage Rz lysis protein Med9 PF07544.13 CRJ83619.1 - 0.089 12.9 0.5 0.14 12.3 0.5 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 THOC7 PF05615.13 CRJ83619.1 - 0.19 12.0 3.1 0.34 11.2 3.1 1.3 1 0 0 1 1 1 0 Tho complex subunit 7 Swi5 PF07061.11 CRJ83619.1 - 0.3 11.2 1.1 0.64 10.2 1.1 1.5 1 0 0 1 1 1 0 Swi5 Torus PF16131.5 CRJ83623.1 - 1.3e-45 154.5 0.1 3.3e-45 153.2 0.1 1.7 1 0 0 1 1 1 1 Torus domain RRM_1 PF00076.22 CRJ83623.1 - 2.9e-07 30.2 0.0 5.3e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 CRJ83623.1 - 0.00013 21.8 0.6 0.00013 21.8 0.6 1.9 2 0 0 2 2 2 1 Zinc finger domain Nup35_RRM_2 PF14605.6 CRJ83623.1 - 0.0091 16.0 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.24 CRJ83623.1 - 0.0097 15.8 0.7 0.021 14.7 0.7 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) MMR_HSR1_Xtn PF16897.5 CRJ83627.1 - 2.3e-35 120.8 1.7 7.2e-35 119.2 0.5 2.1 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 CRJ83627.1 - 9.4e-22 76.8 0.1 1.8e-21 75.9 0.1 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 CRJ83627.1 - 1.8e-20 73.2 0.2 4.7e-20 71.8 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CRJ83627.1 - 1.4e-12 47.4 0.0 2.3e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 CRJ83627.1 - 0.00031 20.8 2.9 0.051 13.6 0.0 2.6 2 1 1 3 3 3 2 Dynamin family MeaB PF03308.16 CRJ83627.1 - 0.066 12.2 0.2 0.16 10.9 0.1 1.7 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MCM PF00493.23 CRJ83627.1 - 0.11 11.6 0.0 0.24 10.5 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain ArgJ PF01960.18 CRJ83633.1 - 1.6e-153 510.9 0.5 8.5e-139 462.5 0.3 2.3 2 0 0 2 2 2 2 ArgJ family AA_permease_2 PF13520.6 CRJ83633.1 - 2.3e-54 184.8 49.9 3.3e-54 184.4 49.9 1.1 1 0 0 1 1 1 1 Amino acid permease Acyl-CoA_dh_1 PF00441.24 CRJ83633.1 - 1.3e-25 90.4 0.2 3.2e-25 89.1 0.2 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain AA_permease PF00324.21 CRJ83633.1 - 5.3e-25 87.9 36.5 7.9e-25 87.4 36.5 1.1 1 0 0 1 1 1 1 Amino acid permease Acyl-CoA_dh_M PF02770.19 CRJ83633.1 - 4.1e-20 71.8 0.0 1e-19 70.5 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Spo12 PF05032.12 CRJ83633.1 - 2.2e-14 53.1 0.6 6e-14 51.7 0.6 1.8 1 0 0 1 1 1 1 Spo12 family Acyl-CoA_dh_N PF02771.16 CRJ83633.1 - 3.1e-13 50.4 0.0 8.2e-13 49.0 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 CRJ83633.1 - 1.5e-10 41.5 0.2 3.4e-10 40.3 0.2 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain GTP_EFTU_D4 PF14578.6 CRJ83633.1 - 0.16 11.9 0.0 31 4.6 0.0 2.8 2 0 0 2 2 2 0 Elongation factor Tu domain 4 RNA_pol_Rpo13 PF12136.8 CRJ83633.1 - 0.24 11.4 6.1 6.7 6.7 0.6 2.5 2 0 0 2 2 2 0 RNA polymerase Rpo13 subunit HTH domain DUF5301 PF17225.3 CRJ83642.1 - 0.015 15.7 1.6 0.036 14.5 0.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF5300) Neur_chan_memb PF02932.16 CRJ83642.1 - 1.2 9.1 4.7 2 8.4 4.7 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3987 PF13148.6 CRJ83642.1 - 3.1 6.7 9.7 4.8 6.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Abhydrolase_1 PF00561.20 CRJ83645.1 - 4.6e-18 65.8 0.0 9e-18 64.8 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CRJ83645.1 - 1.1e-10 41.3 0.0 1.3e-08 34.5 0.0 2.5 3 0 0 3 3 3 2 Serine aminopeptidase, S33 Cohesin_load PF10345.9 CRJ83651.1 - 9.9e-131 437.1 7.2 1.5e-130 436.5 7.2 1.2 1 0 0 1 1 1 1 Cohesin loading factor Pet127 PF08634.10 CRJ83651.1 - 1.4e-119 398.5 1.6 2.6e-119 397.7 1.6 1.5 1 0 0 1 1 1 1 Mitochondrial protein Pet127 Aminotran_5 PF00266.19 CRJ83651.1 - 7.3e-11 41.6 0.0 1.6e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 CRJ83651.1 - 7.1e-05 22.1 0.0 0.00013 21.3 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II DUF1985 PF09331.11 CRJ83651.1 - 0.019 14.9 0.2 0.065 13.2 0.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1985) DUF1761 PF08570.10 CRJ83651.1 - 0.045 14.0 0.2 0.14 12.5 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1761) TPR_16 PF13432.6 CRJ83651.1 - 1.1 10.0 7.2 23 5.8 0.2 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 CRJ83651.1 - 2.6 8.4 9.4 26 5.2 1.2 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 CRJ83651.1 - 7.7 6.9 7.0 39 4.7 1.4 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat RRM_1 PF00076.22 CRJ83659.1 - 1.6e-64 213.6 0.0 1.6e-14 53.5 0.0 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CRJ83659.1 - 1e-07 31.9 0.0 0.041 14.0 0.0 3.2 4 0 0 4 4 4 2 RNA recognition motif RRM_5 PF13893.6 CRJ83659.1 - 9.8e-06 25.2 0.0 0.58 9.7 0.0 3.7 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CRJ83659.1 - 9.2e-05 22.4 0.1 0.68 10.0 0.0 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif DUF2527 PF10736.9 CRJ83659.1 - 0.016 15.0 0.1 8.7 6.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2627) L-fibroin PF05849.11 CRJ83659.1 - 0.02 14.2 0.0 3.7 6.8 0.0 2.1 2 0 0 2 2 2 0 Fibroin light chain (L-fibroin) HiaBD2 PF15403.6 CRJ83659.1 - 0.03 14.7 0.7 13 6.3 0.1 2.6 2 0 0 2 2 2 0 HiaBD2_N domain of Trimeric autotransporter adhesin (GIN) DUF4857 PF16149.5 CRJ83659.1 - 0.031 13.5 0.0 4.4 6.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4857) Limkain-b1 PF11608.8 CRJ83659.1 - 0.034 14.2 0.4 18 5.5 0.1 2.8 2 0 0 2 2 2 0 Limkain b1 DUF5640 PF18692.1 CRJ83659.1 - 0.054 13.5 0.1 18 5.5 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5640) OB_RNB PF08206.11 CRJ83659.1 - 0.074 12.7 9.1 34 4.2 0.2 4.4 4 0 0 4 4 4 0 Ribonuclease B OB domain PHM7_cyt PF14703.6 CRJ83659.1 - 9.3 6.4 9.6 39 4.4 0.0 4.0 5 0 0 5 5 5 0 Cytosolic domain of 10TM putative phosphate transporter Tom7 PF08038.12 CRJ83664.1 - 4.5e-22 77.4 0.1 5.1e-22 77.2 0.1 1.0 1 0 0 1 1 1 1 TOM7 family Tom7 PF08038.12 CRJ83669.1 - 9.1e-22 76.4 0.1 1.1e-21 76.1 0.1 1.1 1 0 0 1 1 1 1 TOM7 family Mito_carr PF00153.27 CRJ83674.1 - 9.6e-77 253.0 4.3 5.4e-19 67.9 0.0 5.0 4 1 1 5 5 5 5 Mitochondrial carrier protein DUF240 PF03086.14 CRJ83674.1 - 0.0056 16.6 0.0 4.8 7.1 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF240) Elf4 PF07011.11 CRJ83674.1 - 0.019 14.8 0.0 8.9 6.3 0.0 2.2 2 0 0 2 2 2 0 Early Flowering 4 domain CSN8_PSD8_EIF3K PF10075.9 CRJ83674.1 - 0.15 12.0 0.0 15 5.5 0.0 2.2 2 0 0 2 2 2 0 CSN8/PSMD8/EIF3K family zf-C2H2 PF00096.26 CRJ83680.1 - 5.4e-18 64.4 33.7 5.3e-05 23.4 1.3 5.5 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CRJ83680.1 - 1.5e-11 44.1 37.7 3.2e-06 27.3 0.8 5.5 6 0 0 6 6 6 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 CRJ83680.1 - 4.1e-10 39.6 27.1 0.042 14.7 0.5 5.6 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_8 PF15909.5 CRJ83680.1 - 0.016 15.5 9.2 0.039 14.2 3.9 3.1 1 1 2 3 3 3 0 C2H2-type zinc ribbon zf-C2H2_11 PF16622.5 CRJ83680.1 - 0.032 14.0 10.6 1.6 8.6 0.1 3.7 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-met PF12874.7 CRJ83680.1 - 0.18 12.2 12.6 1.3 9.5 0.6 4.5 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_aberr PF17017.5 CRJ83680.1 - 0.25 11.5 6.1 13 5.9 0.2 3.3 2 1 1 3 3 3 0 Aberrant zinc-finger zf-C2H2 PF00096.26 CRJ83682.1 - 8.3e-20 70.1 27.7 4.1e-05 23.8 1.3 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CRJ83682.1 - 7.2e-11 42.0 39.6 2.5e-06 27.6 0.8 5.1 6 0 0 6 6 6 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 CRJ83682.1 - 1.7e-10 40.8 25.9 0.033 15.0 0.5 5.3 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_11 PF16622.5 CRJ83682.1 - 0.021 14.6 10.6 1.2 8.9 0.1 3.5 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2H2_8 PF15909.5 CRJ83682.1 - 0.069 13.5 12.9 0.038 14.3 4.3 3.4 2 1 2 4 4 4 0 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 CRJ83682.1 - 0.13 12.4 6.2 9.9 6.3 0.2 3.4 2 1 1 3 3 3 0 Aberrant zinc-finger Urm1 PF09138.11 CRJ83685.1 - 1.4e-12 47.7 0.0 1.7e-12 47.6 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) WD40 PF00400.32 CRJ83688.1 - 4.3e-19 68.5 1.8 4.3e-05 24.2 0.1 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat Urm1 PF09138.11 CRJ83691.1 - 3.1e-35 120.4 0.0 3.5e-35 120.2 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 CRJ83691.1 - 2e-06 28.4 0.0 2.4e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 ThiS family WD40 PF00400.32 CRJ83694.1 - 1.7e-29 101.4 18.5 0.00015 22.5 0.1 10.7 12 0 0 12 12 12 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRJ83694.1 - 3.1e-05 24.2 1.5 17 5.8 0.1 6.7 3 2 4 7 7 7 1 Anaphase-promoting complex subunit 4 WD40 domain SPT_ssu-like PF11779.8 CRJ83697.1 - 5.2e-21 74.0 6.3 1.1e-20 72.9 6.3 1.6 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like WD40 PF00400.32 CRJ83697.1 - 8.1e-10 39.1 8.5 0.00013 22.6 0.1 4.9 5 0 0 5 5 5 2 WD domain, G-beta repeat KR PF08659.10 CRJ83697.1 - 1e-09 38.5 0.2 2.4e-09 37.4 0.2 1.6 1 0 0 1 1 1 1 KR domain PP-binding PF00550.25 CRJ83697.1 - 1.7e-05 25.1 0.3 3.8e-05 24.0 0.3 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site SPT_ssu-like PF11779.8 CRJ83700.1 - 3.4e-22 77.8 6.3 4.6e-22 77.4 6.3 1.2 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like KR PF08659.10 CRJ83703.1 - 1.1e-61 207.9 1.8 4.4e-61 205.9 1.8 2.1 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 CRJ83703.1 - 3.6e-55 187.7 0.1 7e-55 186.8 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 CRJ83703.1 - 5.9e-50 170.2 0.1 1e-49 169.4 0.1 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 CRJ83703.1 - 2.4e-41 140.5 0.0 1.2e-40 138.2 0.0 2.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.26 CRJ83703.1 - 3.2e-28 99.0 0.0 2.9e-20 72.9 0.0 2.9 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain KAsynt_C_assoc PF16197.5 CRJ83703.1 - 6.4e-19 68.5 0.0 8.3e-18 64.9 0.0 2.6 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 CRJ83703.1 - 1e-16 61.0 3.2 1.5e-14 53.9 0.5 2.8 2 0 0 2 2 2 2 short chain dehydrogenase ADH_zinc_N_2 PF13602.6 CRJ83703.1 - 4.4e-11 44.0 0.0 2.4e-10 41.6 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short_C2 PF13561.6 CRJ83703.1 - 1.1e-10 41.5 5.1 3.2e-10 40.0 1.3 2.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase ADH_zinc_N PF00107.26 CRJ83703.1 - 2.4e-09 37.3 0.1 9.3e-09 35.4 0.1 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CRJ83703.1 - 4.1e-05 23.4 0.3 0.00017 21.5 0.0 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 CRJ83703.1 - 5.6e-05 23.4 0.3 0.00013 22.2 0.3 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Polysacc_synt_2 PF02719.15 CRJ83703.1 - 0.0049 16.0 0.0 0.0096 15.1 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein FSH1 PF03959.13 CRJ83706.1 - 2.6e-31 108.9 0.0 7.3e-31 107.5 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) PE-PPE PF08237.11 CRJ83706.1 - 0.051 13.1 0.0 0.078 12.5 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain ABC_membrane PF00664.23 CRJ83708.1 - 1.5e-65 221.5 47.5 2e-42 145.8 15.6 3.2 2 1 2 4 4 4 2 ABC transporter transmembrane region ABC_tran PF00005.27 CRJ83708.1 - 8.5e-62 207.7 0.0 9.5e-30 103.9 0.0 3.0 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.19 CRJ83708.1 - 4.7e-15 55.6 3.1 0.00052 19.5 0.2 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CRJ83708.1 - 5.5e-09 35.6 2.6 0.0027 17.4 0.2 3.5 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_22 PF13401.6 CRJ83708.1 - 1.2e-08 35.3 0.7 0.0033 17.7 0.1 4.0 3 1 0 3 3 3 2 AAA domain ABC_ATPase PF09818.9 CRJ83708.1 - 1e-07 31.1 4.0 0.025 13.4 0.1 4.5 4 1 1 5 5 5 2 Predicted ATPase of the ABC class AAA_30 PF13604.6 CRJ83708.1 - 1.8e-07 31.1 0.8 0.014 15.1 0.2 3.5 3 1 0 3 3 3 2 AAA domain AAA_21 PF13304.6 CRJ83708.1 - 2.7e-06 27.4 1.9 0.034 13.9 0.1 3.1 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CRJ83708.1 - 3e-06 27.9 0.4 0.023 15.2 0.1 2.3 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 CRJ83708.1 - 3.2e-06 27.2 0.0 0.13 12.2 0.0 2.8 3 0 0 3 3 2 2 RsgA GTPase AAA_16 PF13191.6 CRJ83708.1 - 8.7e-06 26.2 3.1 0.065 13.6 0.1 3.3 2 1 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 CRJ83708.1 - 4.1e-05 23.2 0.6 0.33 10.5 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.6 CRJ83708.1 - 7.1e-05 23.4 0.3 0.45 11.1 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_24 PF13479.6 CRJ83708.1 - 0.0001 22.1 0.0 0.28 10.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 CRJ83708.1 - 0.00038 20.3 0.2 0.39 10.4 0.1 2.1 2 0 0 2 2 2 2 AAA ATPase domain Rad17 PF03215.15 CRJ83708.1 - 0.00049 20.1 0.1 0.46 10.4 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_5 PF07728.14 CRJ83708.1 - 0.00054 20.0 0.1 1 9.3 0.0 3.3 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) SRP54 PF00448.22 CRJ83708.1 - 0.0006 19.5 0.6 1.2 8.8 0.0 3.2 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain ATP_bind_1 PF03029.17 CRJ83708.1 - 0.00074 19.4 0.1 1.2 8.8 0.0 2.4 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 CRJ83708.1 - 0.00087 18.9 0.0 1.6 8.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_28 PF13521.6 CRJ83708.1 - 0.0012 19.1 0.1 0.58 10.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CRJ83708.1 - 0.0014 18.8 0.1 2.2 8.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 CRJ83708.1 - 0.0032 17.9 2.2 6.1 7.3 0.3 4.1 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 CRJ83708.1 - 0.0056 16.7 0.1 1.9 8.5 0.0 3.4 4 0 0 4 4 3 1 AAA domain SbcCD_C PF13558.6 CRJ83708.1 - 0.0061 16.8 5.5 0.54 10.5 0.2 4.0 3 2 0 3 3 2 1 Putative exonuclease SbcCD, C subunit PRK PF00485.18 CRJ83708.1 - 0.0074 16.1 0.0 0.75 9.5 0.0 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family DUF87 PF01935.17 CRJ83708.1 - 0.014 15.5 0.5 2.3 8.2 0.0 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain Cytidylate_kin PF02224.18 CRJ83708.1 - 0.015 15.0 0.1 4.2 7.0 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase AAA_19 PF13245.6 CRJ83708.1 - 0.025 14.9 0.7 4.5 7.6 0.1 3.1 3 1 0 3 3 3 0 AAA domain Herpes_Helicase PF02689.14 CRJ83708.1 - 0.034 12.1 0.3 0.26 9.1 0.1 2.4 3 0 0 3 3 3 0 Helicase NB-ARC PF00931.22 CRJ83708.1 - 0.04 13.1 1.0 13 4.9 0.1 3.1 3 0 0 3 3 3 0 NB-ARC domain dNK PF01712.19 CRJ83708.1 - 0.066 13.1 0.1 12 5.7 0.0 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_17 PF13207.6 CRJ83708.1 - 0.081 13.4 0.0 13 6.2 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 CRJ83708.1 - 0.083 12.7 0.3 7.1 6.3 0.0 3.0 2 1 0 2 2 2 0 AAA domain DUF3987 PF13148.6 CRJ83708.1 - 0.095 11.7 0.0 14 4.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) TniB PF05621.11 CRJ83708.1 - 0.1 12.0 0.1 14 5.0 0.0 3.2 3 0 0 3 3 3 0 Bacterial TniB protein DEAD PF00270.29 CRJ83708.1 - 0.13 12.0 0.2 14 5.4 0.1 3.5 3 1 0 3 3 3 0 DEAD/DEAH box helicase APS_kinase PF01583.20 CRJ83708.1 - 0.14 12.0 0.1 12 5.7 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase IstB_IS21 PF01695.17 CRJ83708.1 - 0.14 11.8 1.9 43 3.8 0.0 4.2 5 0 0 5 5 4 0 IstB-like ATP binding protein NACHT PF05729.12 CRJ83708.1 - 0.14 12.0 0.0 14 5.6 0.0 2.5 2 0 0 2 2 2 0 NACHT domain cobW PF02492.19 CRJ83708.1 - 0.41 10.2 3.1 9.3 5.8 0.0 3.0 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain ATPase PF06745.13 CRJ83708.1 - 0.71 9.2 2.7 5.7 6.2 0.2 2.5 3 0 0 3 3 2 0 KaiC MMR_HSR1 PF01926.23 CRJ83708.1 - 0.94 9.6 2.5 27 4.9 0.1 2.8 3 0 0 3 3 2 0 50S ribosome-binding GTPase RF-1 PF00472.20 CRJ83714.1 - 2.7e-24 85.3 2.5 3.9e-24 84.8 2.5 1.2 1 0 0 1 1 1 1 RF-1 domain VWA_N PF08399.11 CRJ83714.1 - 0.4 11.2 2.5 6.2 7.3 0.3 2.3 1 1 1 2 2 2 0 VWA N-terminal Actin PF00022.19 CRJ83716.1 - 4.8e-149 496.4 0.0 1.9e-148 494.4 0.0 1.7 1 1 0 1 1 1 1 Actin Ribosomal_L5_C PF00673.21 CRJ83719.1 - 1.2e-25 89.5 0.0 1.9e-25 88.9 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 CRJ83719.1 - 4e-05 23.9 0.1 7e-05 23.1 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L5 UCH_1 PF13423.6 CRJ83720.1 - 2.1e-31 109.7 0.0 7.1e-31 108.0 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.29 CRJ83720.1 - 9.4e-15 54.8 0.0 1.5e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase 6PF2K PF01591.18 CRJ83721.1 - 2.1e-58 197.3 0.0 3.1e-58 196.7 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 CRJ83721.1 - 2.5e-19 69.8 0.2 1.9e-18 66.8 0.2 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 CRJ83721.1 - 0.017 15.3 0.0 0.12 12.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 CRJ83721.1 - 0.12 12.8 0.0 1.8 9.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF410 PF04190.13 CRJ83722.1 - 3.9e-46 157.9 0.0 5e-46 157.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) Porin_3 PF01459.22 CRJ83722.1 - 2.1e-33 115.9 0.1 2.8e-33 115.5 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic porin Sugar_tr PF00083.24 CRJ83798.1 - 5.2e-23 81.6 4.3 5.8e-23 81.5 4.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRJ83798.1 - 8.5e-11 41.4 6.9 9e-11 41.3 6.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3792 PF12670.7 CRJ83798.1 - 0.00081 19.5 3.9 0.0014 18.7 3.9 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3792) LacY_symp PF01306.19 CRJ83798.1 - 0.015 14.1 0.7 0.017 13.9 0.7 1.0 1 0 0 1 1 1 0 LacY proton/sugar symporter CSN8_PSD8_EIF3K PF10075.9 CRJ83883.1 - 8e-36 123.2 0.0 1.1e-35 122.8 0.0 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family Peptidase_C48 PF02902.19 CRJ83971.1 - 4.5e-06 26.7 0.0 4.9e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain GATase PF00117.28 CRJ84057.1 - 9.3e-32 110.3 0.0 1.3e-31 109.9 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 CRJ84057.1 - 6.1e-06 26.2 0.1 0.0012 18.7 0.1 2.2 1 1 1 2 2 2 2 Peptidase C26 ArfGap PF01412.18 CRJ84057.1 - 0.038 14.1 0.2 0.074 13.1 0.2 1.5 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf Peptidase_C37 PF05416.12 CRJ84287.1 - 0.45 9.0 10.0 0.49 8.8 10.0 1.0 1 0 0 1 1 1 0 Southampton virus-type processing peptidase SURF2 PF05477.11 CRJ84287.1 - 0.81 9.3 18.3 1 9.0 18.3 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) MAJIN PF15077.6 CRJ84287.1 - 4.6 7.0 14.4 4.8 6.9 14.4 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein DUF4820 PF16091.5 CRJ84287.1 - 8.5 5.7 16.6 11 5.3 16.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) RR_TM4-6 PF06459.12 CRJ84287.1 - 9.6 5.9 25.3 11 5.8 25.3 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Glyco_hydro_38C PF07748.13 CRJ84350.1 - 1.4e-29 103.7 0.1 1.7e-29 103.4 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain CHD5 PF04420.14 CRJ84581.1 - 4e-27 95.0 2.1 5.9e-27 94.5 2.1 1.3 1 0 0 1 1 1 1 CHD5-like protein V_ATPase_I PF01496.19 CRJ84586.1 - 4e-132 441.8 1.0 4.5e-132 441.7 1.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family CPSF73-100_C PF11718.8 CRJ84592.1 - 8.5e-81 270.6 0.0 1.2e-80 270.2 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 CRJ84592.1 - 1.4e-29 102.6 0.0 2.7e-29 101.7 0.0 1.5 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_6 PF16661.5 CRJ84592.1 - 2.8e-18 66.1 0.0 4.5e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 CRJ84592.1 - 5e-18 65.8 1.0 9.9e-18 64.9 1.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.12 CRJ84592.1 - 8.1e-12 44.9 0.0 1.7e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_3 PF13483.6 CRJ84592.1 - 5.4e-06 26.4 0.1 1.3e-05 25.1 0.1 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 CRJ84592.1 - 6.8e-06 25.7 0.4 1.9e-05 24.3 0.4 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 CRJ84592.1 - 0.046 12.9 0.0 0.08 12.2 0.0 1.3 1 0 0 1 1 1 0 Putative beta-lactamase-like family CN_hydrolase PF00795.22 CRJ84599.1 - 1.5e-43 149.1 0.0 2.2e-43 148.5 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase TAF4 PF05236.14 CRJ84599.1 - 5.4e-23 82.1 3.0 6.9e-19 68.6 1.4 2.2 2 0 0 2 2 2 2 Transcription initiation factor TFIID component TAF4 family Hydrolase_4 PF12146.8 CRJ84599.1 - 0.1 11.9 0.1 0.2 10.9 0.1 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Pkinase PF00069.25 CRJ84618.1 - 3.2e-49 167.7 0.0 4.9e-49 167.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRJ84618.1 - 1.1e-30 106.9 0.0 1.6e-30 106.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CRJ84618.1 - 0.0017 17.4 0.0 0.0026 16.8 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CRJ84618.1 - 0.033 13.5 0.2 0.057 12.8 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 CRJ84618.1 - 0.043 12.8 0.0 0.058 12.4 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 CRJ84618.1 - 0.45 10.1 2.1 0.39 10.3 0.3 1.7 2 0 0 2 2 2 0 RIO1 family Pkinase PF00069.25 CRJ84625.1 - 1.6e-49 168.7 0.0 2.4e-49 168.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRJ84625.1 - 4.1e-31 108.2 0.0 5.6e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CRJ84625.1 - 0.00086 18.4 0.0 0.0013 17.8 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CRJ84625.1 - 0.021 14.2 0.3 0.036 13.4 0.3 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 CRJ84625.1 - 0.024 13.6 0.0 0.032 13.2 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 CRJ84625.1 - 0.14 11.7 1.8 0.18 11.4 0.2 1.8 2 0 0 2 2 2 0 RIO1 family Stc1 PF12898.7 CRJ84630.1 - 9.8e-16 58.1 0.1 3e-15 56.5 0.1 1.9 1 0 0 1 1 1 1 Stc1 domain BCDHK_Adom3 PF10436.9 CRJ84639.1 - 2.8e-72 241.8 0.0 4.2e-72 241.3 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 CRJ84639.1 - 6.6e-13 49.1 0.0 1.3e-12 48.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CRJ84639.1 - 0.043 13.6 0.0 0.073 12.9 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Tropomyosin_1 PF12718.7 CRJ84645.1 - 0.013 15.7 0.8 0.022 14.9 0.8 1.3 1 0 0 1 1 1 0 Tropomyosin like LigT_PEase PF02834.16 CRJ84645.1 - 0.055 13.7 0.6 0.82 9.9 0.0 2.7 3 0 0 3 3 3 0 LigT like Phosphoesterase NBP1 PF08537.10 CRJ84645.1 - 0.086 12.2 1.1 0.18 11.2 1.1 1.4 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 Lectin_N PF03954.14 CRJ84645.1 - 0.13 12.0 1.2 0.3 10.8 1.2 1.5 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain SAP PF02037.27 CRJ84645.1 - 0.16 11.8 0.1 0.44 10.3 0.1 1.8 1 0 0 1 1 1 0 SAP domain CENP-F_leu_zip PF10473.9 CRJ84645.1 - 0.24 11.4 5.2 0.056 13.5 1.8 1.6 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Sugar_tr PF00083.24 CRJ84651.1 - 8.6e-59 199.6 14.6 1e-58 199.3 14.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRJ84651.1 - 7.9e-06 25.0 34.3 0.0004 19.4 6.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily tRNA-synt_2 PF00152.20 CRJ84651.1 - 0.2 10.7 0.1 0.3 10.1 0.1 1.2 1 0 0 1 1 1 0 tRNA synthetases class II (D, K and N) Glyco_transf_34 PF05637.12 CRJ84658.1 - 7.9e-61 205.8 0.0 1.1e-60 205.3 0.0 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Pyridoxal_deC PF00282.19 CRJ84658.1 - 2.5e-12 46.2 0.0 3.6e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 CRJ84658.1 - 0.00036 19.6 0.0 0.00062 18.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 CRJ84658.1 - 0.057 12.7 0.0 0.092 12.0 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 CRJ84658.1 - 0.087 11.3 0.0 0.14 10.7 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DUF3915 PF13054.6 CRJ84658.1 - 0.75 9.8 2.8 1.7 8.6 2.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Proteasome PF00227.26 CRJ84667.1 - 3.3e-49 167.0 0.0 5e-26 91.4 0.0 2.4 2 0 0 2 2 2 2 Proteasome subunit Ribonuclease_3 PF00636.26 CRJ84667.1 - 6.4e-37 126.4 0.0 5.5e-20 71.9 0.0 2.6 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 CRJ84667.1 - 3.6e-22 78.9 0.0 1.1e-09 38.5 0.0 4.3 3 1 0 3 3 3 2 Ribonuclease-III-like Dicer_dimer PF03368.14 CRJ84667.1 - 2.9e-21 75.4 0.0 6.9e-21 74.2 0.0 1.7 1 0 0 1 1 1 1 Dicer dimerisation domain Helicase_C PF00271.31 CRJ84667.1 - 2.2e-14 53.7 0.0 5.6e-14 52.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CRJ84667.1 - 4.1e-11 42.9 0.0 1.6e-10 41.0 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Proteasome_A_N PF10584.9 CRJ84667.1 - 1.2e-09 37.7 0.0 2.5e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature ResIII PF04851.15 CRJ84667.1 - 0.00011 22.3 0.0 0.00033 20.7 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 CRJ84667.1 - 0.15 11.3 0.1 0.44 9.8 0.1 1.7 1 0 0 1 1 1 0 SecA DEAD-like domain TcpF PF06340.11 CRJ84678.1 - 0.018 14.0 0.0 0.024 13.5 0.0 1.1 1 0 0 1 1 1 0 Vibrio cholerae toxin co-regulated pilus biosynthesis protein F Rgp1 PF08737.10 CRJ84691.1 - 1.1e-257 854.9 0.0 7.4e-98 328.5 0.0 4.4 4 0 0 4 4 4 4 Rgp1 Beta-lactamase PF00144.24 CRJ84691.1 - 2.4e-30 105.9 0.0 1.4e-28 100.1 0.0 2.7 1 1 0 1 1 1 1 Beta-lactamase Neugrin PF06413.11 CRJ84691.1 - 5e-11 43.0 1.2 1.2e-10 41.8 1.2 1.6 1 0 0 1 1 1 1 Neugrin Arrestin_N PF00339.29 CRJ84691.1 - 2.5e-09 37.3 1.2 0.0039 17.3 0.0 3.3 4 0 0 4 4 4 2 Arrestin (or S-antigen), N-terminal domain MRP-L20 PF12824.7 CRJ84691.1 - 1.3e-06 28.6 0.7 8.2e-06 26.1 0.7 2.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Arrestin_C PF02752.22 CRJ84691.1 - 7.7e-06 26.4 0.2 0.93 9.9 0.0 4.2 6 0 0 6 6 6 2 Arrestin (or S-antigen), C-terminal domain Neugrin PF06413.11 CRJ84704.1 - 1.2e-11 45.1 0.4 1.2e-11 45.1 0.4 1.9 2 1 0 2 2 2 1 Neugrin MRP-L20 PF12824.7 CRJ84704.1 - 1.7e-06 28.3 5.8 1.7e-06 28.3 5.8 2.0 2 1 0 2 2 2 1 Mitochondrial ribosomal protein subunit L20 WD40 PF00400.32 CRJ84708.1 - 3e-08 34.2 13.2 0.014 16.3 0.1 7.7 9 0 0 9 9 9 3 WD domain, G-beta repeat TrkA_N PF02254.18 CRJ84708.1 - 0.026 14.8 0.0 0.084 13.1 0.0 1.9 1 0 0 1 1 1 0 TrkA-N domain DUF962 PF06127.11 CRJ84721.1 - 0.031 14.3 0.1 0.18 11.9 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF962) YccF PF03733.13 CRJ84721.1 - 1.3 9.8 7.7 5.5 7.8 1.5 3.0 2 0 0 2 2 2 0 Inner membrane component domain Hydrophobin_2 PF06766.11 CRJ84726.1 - 2.5e-17 62.5 8.1 3.4e-17 62.2 8.1 1.2 1 0 0 1 1 1 1 Fungal hydrophobin Melibiase_2 PF16499.5 CRJ84731.1 - 3.3e-50 170.9 7.7 1e-35 123.3 2.4 2.2 2 0 0 2 2 2 2 Alpha galactosidase A Melibiase_C PF17801.1 CRJ84731.1 - 1.2e-11 44.5 1.6 1.6e-10 40.9 0.0 2.9 3 0 0 3 3 3 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 CRJ84731.1 - 2.8e-05 23.2 0.0 5.2e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Melibiase HET PF06985.11 CRJ84736.1 - 2.3e-19 70.2 0.0 5.8e-19 68.9 0.0 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.16 CRJ84739.1 - 5.6e-13 48.5 59.6 5.8e-07 28.8 21.9 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 CRJ84739.1 - 5.9e-12 45.2 12.9 3.5e-10 39.3 6.9 2.9 2 1 0 2 2 2 2 Sugar (and other) transporter Peptidase_S8 PF00082.22 CRJ84744.1 - 8.8e-40 136.8 3.9 1.4e-39 136.1 3.9 1.4 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 CRJ84744.1 - 0.005 17.5 0.0 0.011 16.4 0.0 1.6 1 0 0 1 1 1 1 Fn3-like domain Ank_2 PF12796.7 CRJ84754.1 - 2.2e-13 50.6 0.3 1.6e-09 38.2 0.4 2.8 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CRJ84754.1 - 1.2e-11 44.9 0.3 1.1e-07 32.3 0.1 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 CRJ84754.1 - 8.3e-09 35.5 0.6 1.5e-06 28.4 0.1 3.3 3 0 0 3 3 3 1 Ankyrin repeat Helo_like_N PF17111.5 CRJ84754.1 - 1.1e-08 34.7 0.0 1.9e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Ank_3 PF13606.6 CRJ84754.1 - 5.8e-08 32.4 0.2 0.00017 21.8 0.0 4.5 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 CRJ84754.1 - 6.6e-06 26.3 0.0 6e-05 23.2 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) SesA PF17107.5 CRJ84754.1 - 0.027 14.7 0.0 0.11 12.8 0.0 2.1 2 1 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases YukD PF08817.10 CRJ84760.1 - 0.0026 18.4 0.0 0.0039 17.8 0.0 1.3 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD ubiquitin PF00240.23 CRJ84760.1 - 0.025 14.3 0.0 0.04 13.7 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin family GFA PF04828.14 CRJ84765.1 - 0.0002 21.6 2.9 0.071 13.5 0.3 2.5 2 1 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme Fer4_21 PF14697.6 CRJ84765.1 - 0.083 13.0 0.9 0.083 13.0 0.9 2.1 2 0 0 2 2 2 0 4Fe-4S dicluster domain API5 PF05918.11 CRJ84771.1 - 0.2 10.5 1.9 0.24 10.2 1.9 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) FAD_binding_3 PF01494.19 CRJ84783.1 - 2.2e-76 257.4 0.0 2.7e-76 257.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 CRJ84783.1 - 9.3e-32 110.3 0.0 1.7e-31 109.5 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 CRJ84783.1 - 4.5e-08 32.7 0.0 0.00016 21.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CRJ84783.1 - 1.4e-05 25.6 0.0 0.0062 17.1 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CRJ84783.1 - 2.2e-05 23.3 0.6 6e-05 21.9 0.3 1.7 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 CRJ84783.1 - 0.00034 20.3 0.2 0.17 11.4 0.1 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CRJ84783.1 - 0.00077 19.6 0.1 0.0019 18.4 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 CRJ84783.1 - 0.0016 17.5 0.5 0.0031 16.6 0.3 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 CRJ84783.1 - 0.0033 16.7 0.0 0.0058 15.9 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 CRJ84783.1 - 0.0072 15.5 0.1 0.011 14.8 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Trp_halogenase PF04820.14 CRJ84783.1 - 0.013 14.3 0.0 0.021 13.7 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Thi4 PF01946.17 CRJ84783.1 - 0.016 14.5 0.0 0.027 13.7 0.0 1.2 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 CRJ84783.1 - 0.054 12.6 0.3 0.11 11.6 0.3 1.4 1 0 0 1 1 1 0 FAD binding domain UDPG_MGDP_dh_N PF03721.14 CRJ84783.1 - 0.079 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain XdhC_C PF13478.6 CRJ84783.1 - 0.081 13.4 0.0 0.21 12.1 0.0 1.8 1 0 0 1 1 1 0 XdhC Rossmann domain Pyr_redox_3 PF13738.6 CRJ84783.1 - 0.14 11.3 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CRJ84783.1 - 0.27 10.5 0.8 0.48 9.7 0.8 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase F-box PF00646.33 CRJ84790.1 - 1.7e-06 27.7 2.8 3.4e-06 26.8 2.8 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 CRJ84790.1 - 0.0005 19.9 2.8 0.001 18.9 2.8 1.6 1 0 0 1 1 1 1 F-box-like FTO_NTD PF12933.7 CRJ84790.1 - 0.15 11.2 0.1 0.56 9.4 0.0 1.9 2 1 0 2 2 2 0 FTO catalytic domain Zn_clus PF00172.18 CRJ84807.1 - 5.5e-08 32.8 8.6 5.5e-08 32.8 8.6 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-met PF12874.7 CRJ84807.1 - 0.0067 16.8 0.7 0.019 15.4 0.7 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CRJ84807.1 - 0.0074 16.5 1.1 0.016 15.5 1.1 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 CRJ84807.1 - 0.11 13.1 1.1 0.28 11.7 1.1 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type TauD PF02668.16 CRJ84816.1 - 8.9e-47 160.1 0.2 1.5e-36 126.6 0.1 2.5 2 0 0 2 2 2 2 Taurine catabolism dioxygenase TauD, TfdA family T5orf172 PF10544.9 CRJ84816.1 - 7.4e-10 39.3 0.1 2.2e-09 37.8 0.1 1.9 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 CRJ84816.1 - 3.6e-05 24.3 0.0 0.0001 22.9 0.0 1.8 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 RloB PF13707.6 CRJ84816.1 - 0.013 15.7 0.0 20 5.3 0.0 3.3 3 0 0 3 3 3 0 RloB-like protein DUF2757 PF10955.8 CRJ84823.1 - 0.001 19.3 1.3 0.0023 18.1 1.3 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2757) Zn-ribbon_8 PF09723.10 CRJ84823.1 - 0.041 14.0 1.5 9.4 6.4 0.0 2.4 2 0 0 2 2 2 0 Zinc ribbon domain Rubredoxin_2 PF18073.1 CRJ84823.1 - 0.15 11.8 2.9 1.6 8.5 0.6 2.5 2 0 0 2 2 2 0 Rubredoxin metal binding domain zinc_ribbon_10 PF10058.9 CRJ84823.1 - 0.16 11.7 2.8 4.1 7.2 0.1 2.6 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein FUR PF01475.19 CRJ84823.1 - 0.52 10.5 1.7 0.55 10.4 0.2 1.8 1 1 1 2 2 2 0 Ferric uptake regulator family IU_nuc_hydro PF01156.19 CRJ84830.1 - 3.8e-82 276.3 0.1 4.5e-82 276.0 0.1 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Glyco_hydro_3_C PF01915.22 CRJ84830.1 - 0.12 12.3 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain IMS PF00817.20 CRJ84837.1 - 2e-37 128.5 0.0 3.7e-37 127.6 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family REV1_C PF16727.5 CRJ84837.1 - 6.6e-27 93.7 0.2 1.3e-26 92.8 0.2 1.5 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain UBM PF14377.6 CRJ84837.1 - 5.4e-18 63.8 9.4 6.9e-07 28.5 2.4 3.9 3 0 0 3 3 3 3 Ubiquitin binding region IMS_C PF11799.8 CRJ84837.1 - 2.8e-12 47.4 0.0 1.1e-11 45.5 0.0 2.1 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain BRCT_2 PF16589.5 CRJ84837.1 - 1.5e-06 28.5 0.0 3.2e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain mCpol PF18182.1 CRJ84837.1 - 0.011 16.0 0.0 0.032 14.5 0.0 1.7 1 0 0 1 1 1 0 minimal CRISPR polymerase domain LIG3_BRCT PF16759.5 CRJ84837.1 - 0.017 15.4 0.0 0.034 14.4 0.0 1.5 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain BRCT PF00533.26 CRJ84837.1 - 0.027 14.8 0.0 0.062 13.7 0.0 1.7 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain IMS_HHH PF11798.8 CRJ84837.1 - 0.038 14.3 0.2 0.43 11.0 0.0 2.8 2 0 0 2 2 2 0 IMS family HHH motif WSC PF01822.19 CRJ84842.1 - 7.3e-16 58.1 6.8 1.1e-15 57.6 6.8 1.3 1 0 0 1 1 1 1 WSC domain Mito_carr PF00153.27 CRJ84846.1 - 4.4e-66 218.9 1.0 1.1e-21 76.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3349 PF11829.8 CRJ84853.1 - 0.038 14.8 0.0 0.069 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3349) Sod_Fe_C PF02777.18 CRJ84857.1 - 7.2e-05 22.9 0.0 0.00026 21.1 0.0 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 CRJ84857.1 - 0.0038 17.6 0.2 0.0051 17.3 0.2 1.2 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Rota_Capsid_VP6 PF00980.17 CRJ84857.1 - 0.16 10.9 0.1 0.17 10.8 0.1 1.1 1 0 0 1 1 1 0 Rotavirus major capsid protein VP6 Helicase_C PF00271.31 CRJ85158.1 - 1.5e-06 28.5 0.3 2.8e-06 27.6 0.1 1.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DASH_Dad4 PF08650.10 CRJ85158.1 - 0.0095 15.9 0.2 0.014 15.3 0.2 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad4 HAUS6_N PF14661.6 CRJ85158.1 - 0.065 12.8 1.3 0.065 12.8 1.3 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus IBR PF01485.21 CRJ85331.1 - 6e-06 26.4 6.4 6e-06 26.4 6.4 1.9 2 0 0 2 2 2 1 IBR domain, a half RING-finger domain TPR_16 PF13432.6 CRJ85491.1 - 9.1e-11 42.2 0.2 1.1e-05 25.9 0.4 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 CRJ85491.1 - 5.7e-10 38.7 3.0 2.3e-09 36.8 0.5 2.5 3 0 0 3 3 3 1 TPR repeat TPR_1 PF00515.28 CRJ85491.1 - 1.7e-08 33.9 0.2 2.9e-06 26.9 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 CRJ85491.1 - 6.8e-08 32.9 2.6 5.6e-06 26.8 0.7 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 CRJ85491.1 - 1.2e-07 31.9 1.2 5e-05 23.8 0.8 3.1 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 CRJ85491.1 - 1.4e-07 31.1 2.0 1.3e-06 28.0 0.1 3.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 CRJ85491.1 - 6e-07 29.4 0.1 0.06 13.8 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 CRJ85491.1 - 4.3e-06 26.5 0.1 0.0014 18.7 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 CRJ85491.1 - 1.7e-05 24.9 0.1 0.00013 22.1 0.5 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CRJ85491.1 - 2.1e-05 24.7 0.2 3.3e-05 24.0 0.2 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 CRJ85491.1 - 3.8e-05 23.9 0.6 0.039 14.2 0.5 2.6 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 CRJ85491.1 - 5.7e-05 22.9 0.4 0.00034 20.4 0.1 2.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 CRJ85491.1 - 0.00083 19.1 1.0 0.32 10.9 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CRJ85491.1 - 0.0009 19.3 0.4 1.1 9.4 0.1 2.3 2 0 0 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 CRJ85491.1 - 0.0023 18.5 1.6 0.19 12.4 0.1 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.6 CRJ85491.1 - 0.012 15.9 1.5 0.46 10.9 0.2 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_5 PF12688.7 CRJ85491.1 - 0.03 14.6 0.1 1.4 9.2 0.0 2.2 2 0 0 2 2 2 0 Tetratrico peptide repeat MIT PF04212.18 CRJ85491.1 - 0.3 11.2 2.3 0.79 9.8 0.4 2.4 2 1 2 4 4 4 0 MIT (microtubule interacting and transport) domain G6PD_C PF02781.16 CRJ85625.1 - 2.3e-26 92.7 0.0 2.9e-26 92.4 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain Amino_oxidase PF01593.24 CRJ85631.1 - 1.4e-22 80.6 0.0 1.9e-22 80.2 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CRJ85631.1 - 7.4e-13 48.5 0.0 2e-12 47.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CRJ85631.1 - 2e-08 34.2 0.5 1.9e-07 31.0 0.5 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase zf-CCCH_2 PF14608.6 CRJ85631.1 - 2.4e-08 34.1 49.2 0.00062 20.2 14.3 4.8 4 1 0 4 4 4 3 RNA-binding, Nab2-type zinc finger Pyr_redox PF00070.27 CRJ85631.1 - 7.6e-06 26.4 0.1 0.0021 18.6 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CRJ85631.1 - 8e-06 25.3 0.0 0.00035 19.9 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CRJ85631.1 - 0.002 17.3 0.0 0.0032 16.7 0.0 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 CRJ85631.1 - 0.0034 17.4 0.0 0.0099 15.9 0.0 1.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding MCRA PF06100.11 CRJ85631.1 - 0.0043 15.9 0.0 0.0064 15.3 0.0 1.2 1 0 0 1 1 1 1 MCRA family Thi4 PF01946.17 CRJ85631.1 - 0.012 14.9 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.14 CRJ85631.1 - 0.21 10.4 0.5 0.32 9.8 0.5 1.2 1 0 0 1 1 1 0 Tryptophan halogenase p450 PF00067.22 CRJ85640.1 - 2.8e-59 201.1 0.0 3.8e-59 200.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 tRNA-synt_2b PF00587.25 CRJ85647.1 - 7.7e-34 117.2 0.0 1.3e-33 116.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 CRJ85647.1 - 9.3e-16 58.0 5.9 2.1e-15 56.9 5.9 1.6 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Alpha-2-MRAP_C PF06401.11 CRJ85647.1 - 0.016 15.2 3.0 0.026 14.5 3.0 1.3 1 0 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain Aminotran_1_2 PF00155.21 CRJ85656.1 - 1.7e-17 63.7 0.0 2.1e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 CRJ85656.1 - 1.2e-07 30.9 0.0 2.7e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase DegT_DnrJ_EryC1 PF01041.17 CRJ85656.1 - 0.023 14.0 0.0 0.24 10.6 0.0 2.0 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Glyco_hydro_16 PF00722.21 CRJ85664.1 - 3.9e-31 107.9 0.8 5.7e-31 107.4 0.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Topo_C_assoc PF14370.6 CRJ85671.1 - 2.8e-31 107.3 0.2 1.3e-30 105.1 0.2 2.3 1 0 0 1 1 1 1 C-terminal topoisomerase domain Topoisom_I PF01028.20 CRJ85671.1 - 2.8e-22 79.1 0.1 8.7e-22 77.5 0.1 1.8 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core ATP-synt PF00231.19 CRJ85680.1 - 2.4e-60 204.6 5.6 1.7e-43 149.4 0.2 2.0 1 1 1 2 2 2 2 ATP synthase Amino_oxidase PF01593.24 CRJ85689.1 - 4.7e-29 102.0 0.0 1.5e-27 97.1 0.0 2.2 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase SWIRM PF04433.17 CRJ85689.1 - 2.3e-13 50.3 0.0 4.9e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 SWIRM domain HMG_box PF00505.19 CRJ85689.1 - 6.1e-08 33.0 3.1 6.1e-08 33.0 3.1 2.4 2 0 0 2 2 2 1 HMG (high mobility group) box NAD_binding_8 PF13450.6 CRJ85689.1 - 1.9e-07 31.2 0.0 4.2e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HMG_box_2 PF09011.10 CRJ85689.1 - 5.3e-07 30.1 2.3 1.3e-06 28.9 2.3 1.7 1 0 0 1 1 1 1 HMG-box domain Pyr_redox_2 PF07992.14 CRJ85689.1 - 1.6e-05 24.3 0.0 0.00041 19.7 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CRJ85689.1 - 0.00089 18.9 0.0 0.0018 17.9 0.0 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 CRJ85689.1 - 0.073 13.6 0.1 0.27 11.8 0.1 2.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pkinase PF00069.25 CRJ85701.1 - 3.4e-68 229.9 0.0 4.7e-68 229.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRJ85701.1 - 3.3e-34 118.3 0.4 7.2e-34 117.2 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CRJ85701.1 - 6.1e-06 25.8 0.0 1.1e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CRJ85701.1 - 0.00034 20.0 0.0 0.00089 18.7 0.0 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 CRJ85701.1 - 0.0082 15.7 0.0 0.059 12.9 0.0 2.4 3 0 0 3 3 3 1 PhoP regulatory network protein YrbL SLAC1 PF03595.17 CRJ85716.1 - 2.2e-94 316.4 54.1 2.5e-94 316.2 54.1 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF5056 PF16479.5 CRJ85716.1 - 7.8 6.8 7.4 0.29 11.4 0.5 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF5056) tRNA-synt_His PF13393.6 CRJ85722.1 - 1.3e-34 119.9 0.0 2.9e-28 99.0 0.0 2.3 2 0 0 2 2 2 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 CRJ85722.1 - 2.3e-12 46.9 0.0 4.3e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 CRJ85722.1 - 0.00017 21.6 0.0 0.00037 20.5 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.20 CRJ85722.1 - 0.0005 19.2 0.0 0.0015 17.7 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) adh_short_C2 PF13561.6 CRJ85734.1 - 1.3e-34 119.8 0.2 4.2e-34 118.1 0.1 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRJ85734.1 - 4.3e-30 104.6 0.0 8.6e-30 103.7 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Fungal_trans PF04082.18 CRJ85734.1 - 4.5e-13 48.8 0.1 9.9e-13 47.7 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 CRJ85734.1 - 3.9e-11 42.8 8.5 8.4e-05 22.8 0.2 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type Hydrolase_4 PF12146.8 CRJ85734.1 - 1.4e-10 40.9 0.0 3.1e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CRJ85734.1 - 2.1e-09 38.3 10.0 1.4e-08 35.6 10.0 2.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CRJ85734.1 - 6.9e-08 32.4 0.1 1.5e-07 31.3 0.1 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold zf-C2H2_4 PF13894.6 CRJ85734.1 - 2.7e-07 30.8 7.3 0.016 16.0 0.1 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger Zn_clus PF00172.18 CRJ85734.1 - 8.3e-05 22.6 9.6 8.3e-05 22.6 9.6 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-H2C2_2 PF13465.6 CRJ85734.1 - 0.0012 19.2 7.6 0.0012 19.1 0.3 3.2 3 0 0 3 3 3 1 Zinc-finger double domain KR PF08659.10 CRJ85734.1 - 0.002 18.1 0.1 0.0062 16.5 0.1 1.7 1 1 0 1 1 1 1 KR domain zf-C2H2_jaz PF12171.8 CRJ85734.1 - 0.012 15.9 4.8 0.58 10.5 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CRJ85734.1 - 0.052 14.0 3.1 3.7 8.1 1.2 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 CRJ85734.1 - 0.14 12.0 5.1 5.7 6.8 0.1 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-Di19 PF05605.12 CRJ85734.1 - 0.23 11.8 2.2 0.54 10.6 2.2 1.7 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 CRJ85734.1 - 0.8 9.8 3.4 0.35 10.9 0.1 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger ABC_membrane PF00664.23 CRJ85747.1 - 4.8e-76 256.0 41.8 6.3e-43 147.4 14.4 3.1 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 CRJ85747.1 - 8e-62 207.8 0.1 2.2e-31 109.2 0.0 3.4 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CRJ85747.1 - 7.3e-12 45.2 14.3 2.9e-05 23.6 2.4 4.6 3 2 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CRJ85747.1 - 6.2e-08 33.2 0.7 0.029 14.8 0.0 3.6 4 0 0 4 4 3 2 AAA ATPase domain ABC_ATPase PF09818.9 CRJ85747.1 - 5.6e-07 28.7 0.2 0.089 11.6 0.0 3.2 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_29 PF13555.6 CRJ85747.1 - 6e-07 29.1 1.0 0.00048 19.8 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CRJ85747.1 - 1.1e-05 25.4 0.0 0.066 13.1 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 CRJ85747.1 - 1.4e-05 25.4 1.1 0.32 11.3 0.1 3.5 3 1 0 3 3 3 2 AAA domain AAA PF00004.29 CRJ85747.1 - 3.9e-05 24.1 0.9 26 5.2 0.0 4.7 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 CRJ85747.1 - 5.4e-05 23.1 0.2 0.44 10.2 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 CRJ85747.1 - 0.00013 21.9 0.0 0.61 9.8 0.0 3.4 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF1802 PF08819.11 CRJ85747.1 - 0.00055 19.8 0.3 1.5 8.6 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF1802) TMCO5 PF14992.6 CRJ85747.1 - 0.00058 19.5 0.0 1.2 8.6 0.0 2.4 2 0 0 2 2 2 2 TMCO5 family ATP-synt_ab PF00006.25 CRJ85747.1 - 0.00069 19.3 0.0 0.64 9.6 0.0 2.6 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain DUF3987 PF13148.6 CRJ85747.1 - 0.00096 18.3 0.0 0.0024 17.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3987) AAA_30 PF13604.6 CRJ85747.1 - 0.0013 18.5 1.7 0.81 9.4 0.1 3.5 3 1 0 3 3 3 1 AAA domain AAA_5 PF07728.14 CRJ85747.1 - 0.0016 18.4 1.7 2.8 7.9 0.0 3.8 5 1 0 5 5 3 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 CRJ85747.1 - 0.0032 17.0 0.2 2.3 7.7 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_25 PF13481.6 CRJ85747.1 - 0.0035 16.9 0.4 1.4 8.5 0.0 3.6 4 0 0 4 4 4 1 AAA domain SbcCD_C PF13558.6 CRJ85747.1 - 0.0045 17.2 2.6 2.6 8.3 0.3 4.0 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 CRJ85747.1 - 0.017 15.6 7.8 0.091 13.3 0.2 3.3 2 1 1 3 3 3 0 AAA domain PRK PF00485.18 CRJ85747.1 - 0.017 14.9 0.0 7.8 6.2 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_14 PF13173.6 CRJ85747.1 - 0.019 15.0 0.1 2.1 8.4 0.0 3.3 3 0 0 3 3 3 0 AAA domain ATP-synt_E PF05680.12 CRJ85747.1 - 0.029 14.7 5.2 14 6.1 0.0 3.6 3 0 0 3 3 3 0 ATP synthase E chain G-alpha PF00503.20 CRJ85747.1 - 0.043 13.0 0.1 7.4 5.6 0.1 2.3 2 0 0 2 2 2 0 G-protein alpha subunit AAA_18 PF13238.6 CRJ85747.1 - 0.053 14.1 0.1 5.3 7.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 CRJ85747.1 - 0.053 12.7 0.4 6.9 5.8 0.0 2.9 3 0 0 3 3 3 0 NB-ARC domain AAA_10 PF12846.7 CRJ85747.1 - 0.072 12.0 0.6 0.16 10.9 0.1 1.8 2 0 0 2 2 2 0 AAA-like domain ATP_bind_1 PF03029.17 CRJ85747.1 - 0.072 12.9 0.1 0.81 9.4 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_33 PF13671.6 CRJ85747.1 - 0.075 13.2 0.1 2.9 8.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 CRJ85747.1 - 0.077 12.9 0.2 6.9 6.5 0.0 2.6 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_28 PF13521.6 CRJ85747.1 - 0.092 13.0 0.1 17 5.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF592 PF04574.13 CRJ85747.1 - 0.093 12.5 6.4 2.7 7.8 0.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF592) AAA_24 PF13479.6 CRJ85747.1 - 0.1 12.3 0.2 8.3 6.1 0.1 2.4 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 CRJ85747.1 - 0.12 12.1 0.2 13 5.5 0.0 3.0 3 0 0 3 3 2 0 IstB-like ATP binding protein DUF2098 PF09871.9 CRJ85747.1 - 0.38 11.1 12.7 2.2 8.7 0.5 3.3 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2098) AAA_17 PF13207.6 CRJ85747.1 - 1.1 9.7 3.2 3.1 8.2 0.1 2.8 3 0 0 3 3 2 0 AAA domain DUF3546 PF12066.8 CRJ85763.1 - 3.5e-61 204.2 12.1 4.7e-32 110.5 2.4 3.9 4 0 0 4 4 3 2 Domain of unknown function (DUF3546) Mito_carr PF00153.27 CRJ85763.1 - 9.2e-46 153.7 0.1 4.5e-17 61.8 0.0 3.8 3 0 0 3 3 3 3 Mitochondrial carrier protein DEAD PF00270.29 CRJ85763.1 - 4.2e-45 153.7 0.0 4e-44 150.5 0.0 2.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase ABC_membrane PF00664.23 CRJ85763.1 - 8e-33 114.2 15.0 1.4e-32 113.5 15.0 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region Helicase_C PF00271.31 CRJ85763.1 - 2.8e-26 92.0 0.1 5.6e-26 91.1 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ARS2 PF04959.13 CRJ85763.1 - 4.4e-25 89.2 6.2 7.1e-12 46.1 0.1 3.0 3 0 0 3 3 2 2 Arsenite-resistance protein 2 DUF4187 PF13821.6 CRJ85763.1 - 1.5e-24 85.5 3.1 3.7e-11 42.6 0.2 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF4187) ABC_tran PF00005.27 CRJ85763.1 - 2.7e-07 31.2 0.1 1.5e-06 28.8 0.1 2.2 1 1 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 CRJ85763.1 - 0.0006 19.5 0.1 0.0017 18.1 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF3987 PF13148.6 CRJ85763.1 - 0.013 14.5 0.0 0.013 14.5 0.0 3.2 3 0 0 3 3 2 0 Protein of unknown function (DUF3987) AAA_16 PF13191.6 CRJ85763.1 - 0.053 13.9 1.5 0.19 12.1 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain RsgA_GTPase PF03193.16 CRJ85763.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase DUF87 PF01935.17 CRJ85763.1 - 0.13 12.3 0.1 4.3 7.4 0.0 3.2 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_22 PF13401.6 CRJ85763.1 - 0.67 10.2 3.1 1.1 9.5 0.0 3.0 4 0 0 4 4 4 0 AAA domain AAA_15 PF13175.6 CRJ85763.1 - 7 6.3 7.4 0.13 11.9 0.0 1.7 3 0 0 3 3 1 0 AAA ATPase domain TspO_MBR PF03073.15 CRJ85772.1 - 1.3e-43 148.3 7.5 1.7e-43 147.9 7.5 1.1 1 0 0 1 1 1 1 TspO/MBR family Mitoc_mL59 PF18126.1 CRJ85782.1 - 1.5e-27 96.4 0.1 2.6e-27 95.7 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein mL59 TspO_MBR PF03073.15 CRJ85794.1 - 9.6e-43 145.5 2.8 1.8e-42 144.6 2.8 1.4 1 1 0 1 1 1 1 TspO/MBR family Mito_carr PF00153.27 CRJ85801.1 - 2.7e-55 184.3 0.0 1.4e-18 66.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Mitoc_mL59 PF18126.1 CRJ85809.1 - 1.6e-42 144.9 1.8 2.1e-42 144.5 1.8 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein mL59 AICARFT_IMPCHas PF01808.18 CRJ85819.1 - 5.3e-92 308.4 0.0 7.1e-92 308.0 0.0 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 CRJ85819.1 - 2e-24 85.6 0.0 3.8e-24 84.7 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain Lactamase_B_2 PF12706.7 CRJ85819.1 - 0.012 15.1 0.0 11 5.5 0.0 3.3 3 1 1 4 4 4 0 Beta-lactamase superfamily domain IATP PF04568.12 CRJ85825.1 - 1.5e-27 95.9 2.7 1.7e-27 95.7 2.7 1.0 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP DUF2205 PF10224.9 CRJ85825.1 - 0.063 13.3 4.2 0.096 12.7 4.2 1.2 1 0 0 1 1 1 0 Short coiled-coil protein Jagunal PF07086.12 CRJ85825.1 - 0.18 11.9 0.1 0.24 11.5 0.1 1.2 1 0 0 1 1 1 0 Jagunal, ER re-organisation during oogenesis DUF1003 PF06210.11 CRJ85825.1 - 0.76 9.9 2.8 1.2 9.3 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) FokI_C PF02980.16 CRJ85832.1 - 0.091 12.8 0.0 0.098 12.7 0.0 1.1 1 0 0 1 1 1 0 Restriction endonuclease FokI, catalytic domain eIF2_C PF09173.11 CRJ85840.1 - 4.4e-33 113.4 0.5 8.6e-33 112.4 0.5 1.5 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 CRJ85840.1 - 2.6e-21 76.1 0.1 8.3e-21 74.4 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 CRJ85840.1 - 1.9e-09 37.8 0.2 3.4e-09 37.0 0.2 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Ninjurin PF04923.12 CRJ85840.1 - 2.2e-05 24.3 1.5 0.28 11.1 0.1 2.9 2 0 0 2 2 2 2 Ninjurin Zip PF02535.22 CRJ85840.1 - 0.0038 16.5 0.9 2.4 7.3 0.1 2.4 2 0 0 2 2 2 2 ZIP Zinc transporter MARVEL PF01284.23 CRJ85840.1 - 0.015 15.3 20.9 0.56 10.2 6.5 2.8 2 0 0 2 2 2 0 Membrane-associating domain MMR_HSR1 PF01926.23 CRJ85840.1 - 0.025 14.7 0.0 0.051 13.7 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Gpr1_Fun34_YaaH PF01184.19 CRJ85840.1 - 0.053 13.1 7.5 1.8 8.1 0.9 2.4 2 0 0 2 2 2 0 GPR1/FUN34/yaaH family CrgA PF06781.12 CRJ85840.1 - 1.1 9.4 8.4 11 6.2 1.1 2.8 2 0 0 2 2 2 0 Cell division protein CrgA Ion_trans PF00520.31 CRJ85840.1 - 5.4 6.2 13.6 9.3 5.4 3.0 2.7 2 2 0 2 2 2 0 Ion transport protein EBP PF05241.12 CRJ85840.1 - 6.2 6.2 8.3 16 4.9 1.1 2.4 2 0 0 2 2 2 0 Emopamil binding protein DUF4538 PF15061.6 CRJ85840.1 - 9.8 6.0 6.9 34 4.3 0.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) DUF5102 PF17104.5 CRJ85854.1 - 9.3e-110 367.2 6.3 9.3e-110 367.2 6.3 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF5102) RRN3 PF05327.11 CRJ85854.1 - 7.4 5.0 11.7 0.34 9.4 6.0 1.5 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 DUF5102 PF17104.5 CRJ85861.1 - 1.1e-108 363.6 5.0 1.1e-108 363.6 5.0 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF5102) UNC119_bdg PF15435.6 CRJ85861.1 - 0.35 10.4 2.3 2.1 7.9 0.3 2.1 2 0 0 2 2 2 0 UNC119-binding protein C5orf30 homologue Adaptin_binding PF10199.9 CRJ85861.1 - 0.75 10.4 11.6 1.5 9.4 3.7 2.6 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 eIF2_C PF09173.11 CRJ85871.1 - 7.6e-34 115.8 0.5 1.6e-33 114.8 0.5 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 CRJ85871.1 - 3.8e-17 62.5 0.0 6.5e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 CRJ85871.1 - 3.2e-10 40.2 0.2 6.3e-10 39.3 0.2 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1_Xtn PF16897.5 CRJ85871.1 - 0.034 14.2 0.4 0.14 12.2 0.0 2.0 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain Dak1_2 PF13684.6 CRJ85871.1 - 0.17 10.9 0.2 0.33 10.0 0.2 1.4 1 0 0 1 1 1 0 Dihydroxyacetone kinase family Nsp1_C PF05064.13 CRJ85880.1 - 2.3e-62 207.9 1.8 1.4e-37 128.1 0.3 2.5 2 0 0 2 2 2 2 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 CRJ85880.1 - 1.1e-32 112.7 328.5 4e-06 27.6 23.5 13.3 3 2 10 13 13 13 11 Nucleoporin FG repeat region SLATT_fungal PF18142.1 CRJ85880.1 - 0.021 14.8 3.9 1.2 9.2 0.4 3.3 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain Trs65 PF12735.7 CRJ85880.1 - 0.18 11.2 0.0 11 5.3 0.0 2.4 2 0 0 2 2 2 0 TRAPP trafficking subunit Trs65 IATP PF04568.12 CRJ85887.1 - 7.1e-27 93.7 2.5 9e-27 93.4 2.5 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP DUF2205 PF10224.9 CRJ85887.1 - 0.21 11.6 3.7 0.33 11.0 3.7 1.3 1 0 0 1 1 1 0 Short coiled-coil protein DAHP_synth_1 PF00793.20 CRJ85899.1 - 1.4e-163 542.4 0.8 5.2e-77 258.4 0.0 3.3 2 1 1 3 3 3 3 DAHP synthetase I family Cytochrom_C1 PF02167.15 CRJ85899.1 - 3.2e-90 301.7 0.0 5e-90 301.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 CRJ85899.1 - 0.015 15.6 0.1 0.077 13.3 0.0 2.3 2 0 0 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III PASTA PF03793.19 CRJ85899.1 - 0.11 12.4 3.1 36 4.3 0.0 3.7 4 0 0 4 4 4 0 PASTA domain ACT_4 PF13291.6 CRJ85899.1 - 0.44 11.2 3.0 14 6.3 0.2 2.7 2 0 0 2 2 2 0 ACT domain F-box PF00646.33 CRJ85907.1 - 0.00019 21.2 2.6 0.00053 19.8 0.4 2.5 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 CRJ85907.1 - 0.00056 19.8 0.9 0.0093 15.8 0.1 2.5 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.7 CRJ85921.1 - 1.3e-05 25.0 0.7 0.00058 19.7 0.1 2.4 2 0 0 2 2 2 2 F-box-like F-box PF00646.33 CRJ85921.1 - 0.0014 18.5 0.1 0.0014 18.5 0.1 2.3 3 0 0 3 3 3 1 F-box domain JUPITER PF17054.5 CRJ85929.1 - 0.0046 16.5 0.1 0.0058 16.2 0.1 1.1 1 0 0 1 1 1 1 Microtubule-Associated protein Jupiter AAA PF00004.29 CRJ85934.1 - 2.8e-40 137.8 0.0 5.3e-40 136.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CRJ85934.1 - 2.2e-07 30.5 0.0 5.3e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 CRJ85934.1 - 7.4e-05 22.8 0.1 0.00062 19.8 0.0 2.5 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CRJ85934.1 - 0.00012 22.3 0.0 0.0055 17.0 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.14 CRJ85934.1 - 0.00046 20.4 0.0 0.0016 18.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 CRJ85934.1 - 0.00067 20.1 0.1 0.014 15.8 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 CRJ85934.1 - 0.0015 17.8 0.0 0.0027 16.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 CRJ85934.1 - 0.0091 15.8 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 CRJ85934.1 - 0.021 15.1 0.0 0.063 13.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 CRJ85934.1 - 0.029 14.1 0.1 0.59 9.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CRJ85934.1 - 0.033 13.7 0.0 0.095 12.2 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 CRJ85934.1 - 0.049 13.8 0.0 0.095 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CRJ85934.1 - 0.057 13.8 0.0 0.15 12.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.11 CRJ85934.1 - 0.08 12.8 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 CRJ85934.1 - 0.093 12.8 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CRJ85934.1 - 0.098 12.4 0.0 0.28 10.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 CRJ85934.1 - 0.16 11.4 0.0 0.36 10.2 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI FYVE PF01363.21 CRJ85945.1 - 4.6e-21 74.7 1.9 4.6e-21 74.7 1.9 3.0 3 0 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.6 CRJ85945.1 - 3.1e-07 30.6 4.6 3.1e-07 30.6 4.6 4.0 4 0 0 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.6 CRJ85945.1 - 0.0002 21.1 3.7 0.0002 21.1 3.7 3.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CRJ85945.1 - 0.0011 18.6 4.5 0.0011 18.6 4.5 3.0 3 0 0 3 3 3 1 RING-like zinc finger FYVE_2 PF02318.16 CRJ85945.1 - 0.011 15.9 1.2 0.011 15.9 1.2 2.3 2 0 0 2 2 2 0 FYVE-type zinc finger zf-RING-like PF08746.11 CRJ85945.1 - 0.013 15.8 3.3 0.013 15.8 3.3 2.5 2 0 0 2 2 1 0 RING-like domain DZR PF12773.7 CRJ85945.1 - 0.069 13.2 8.3 1.3 9.2 4.7 2.9 2 0 0 2 2 2 0 Double zinc ribbon zf-piccolo PF05715.13 CRJ85945.1 - 0.15 12.2 14.0 0.064 13.4 4.9 2.9 3 0 0 3 3 2 0 Piccolo Zn-finger Rad50_zn_hook PF04423.14 CRJ85945.1 - 0.25 11.2 3.7 0.18 11.7 0.8 2.1 2 0 0 2 2 2 0 Rad50 zinc hook motif zinc_ribbon_2 PF13240.6 CRJ85945.1 - 3.9 7.3 8.0 8.6 6.2 0.1 3.5 3 0 0 3 3 3 0 zinc-ribbon domain zf-RING_UBOX PF13445.6 CRJ85945.1 - 5.4 7.1 26.7 0.08 13.0 4.7 3.7 3 0 0 3 3 3 0 RING-type zinc-finger Anp1 PF03452.14 CRJ85953.1 - 3.5e-106 354.4 0.0 4.2e-106 354.2 0.0 1.1 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 CRJ85953.1 - 0.089 12.6 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 DUF996 PF06195.13 CRJ85953.1 - 0.17 12.2 0.2 0.27 11.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF996) UQ_con PF00179.26 CRJ85962.1 - 6e-27 94.0 0.0 1.3e-26 93.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Spt5_N PF11942.8 CRJ85962.1 - 1.4 10.0 8.1 3.9 8.5 8.1 1.7 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Sec6 PF06046.13 CRJ86220.1 - 7.6e-20 70.8 0.1 8.6e-20 70.6 0.1 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec6 ERAP1_C PF11838.8 CRJ86330.1 - 2.5e-28 99.6 0.0 2.7e-28 99.4 0.0 1.0 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Cyt-b5 PF00173.28 CRJ86658.1 - 9.3e-19 67.4 0.1 2.4e-18 66.1 0.1 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 CRJ86658.1 - 6.9e-12 45.4 0.3 1.2e-11 44.7 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 CRJ86658.1 - 5.9e-11 43.0 0.0 9.3e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain tRNA_bind_2 PF13725.6 CRJ86731.1 - 5.2e-81 271.8 0.1 6.9e-81 271.4 0.1 1.2 1 0 0 1 1 1 1 Possible tRNA binding domain GNAT_acetyltr_2 PF13718.6 CRJ86731.1 - 1.7e-39 135.6 0.0 2.6e-39 135.0 0.0 1.2 1 0 0 1 1 1 1 GNAT acetyltransferase 2 NAPRTase PF04095.16 CRJ86731.1 - 6.2e-18 65.3 0.0 1e-17 64.6 0.0 1.4 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family DprA_WH PF17782.1 CRJ86731.1 - 0.12 12.5 0.1 0.29 11.3 0.1 1.6 1 0 0 1 1 1 0 DprA winged helix domain PolyA_pol PF01743.20 CRJ86825.1 - 1.9e-07 31.5 0.0 2.9e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Poly A polymerase head domain Aldo_ket_red PF00248.21 CRJ87016.1 - 7.1e-42 143.6 0.3 4.3e-41 141.0 0.3 1.8 1 1 0 1 1 1 1 Aldo/keto reductase family CW_binding_2 PF04122.12 CRJ87016.1 - 0.1 13.2 0.1 0.2 12.3 0.1 1.5 1 0 0 1 1 1 0 Putative cell wall binding repeat 2 Velvet PF11754.8 CRJ87028.1 - 6.2e-06 26.3 0.1 2.3e-05 24.5 0.1 1.8 1 1 0 1 1 1 1 Velvet factor Peptidase_S8 PF00082.22 CRJ87036.1 - 6.5e-43 147.1 1.0 1.1e-42 146.4 1.0 1.4 1 0 0 1 1 1 1 Subtilase family PA PF02225.22 CRJ87036.1 - 2e-06 27.7 0.1 9.7e-06 25.5 0.0 2.2 2 0 0 2 2 2 1 PA domain fn3_5 PF06280.12 CRJ87036.1 - 7.5e-05 23.4 0.0 0.043 14.5 0.0 2.7 1 1 0 1 1 1 1 Fn3-like domain FlgD_ig PF13860.6 CRJ87036.1 - 0.0012 18.7 0.1 0.0073 16.1 0.0 2.3 2 0 0 2 2 2 1 FlgD Ig-like domain BolA PF01722.18 CRJ87044.1 - 1.1e-09 38.4 0.0 2.7e-09 37.2 0.0 1.7 1 1 0 1 1 1 1 BolA-like protein Cyclin PF08613.11 CRJ87053.1 - 8.7e-45 153.0 0.0 1.5e-44 152.2 0.0 1.3 1 0 0 1 1 1 1 Cyclin Pex14_N PF04695.13 CRJ87053.1 - 0.035 14.7 0.3 0.035 14.7 0.3 1.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PRIMA1 PF16101.5 CRJ87053.1 - 3.7 7.6 6.5 6.9 6.7 2.2 2.4 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Pellino PF04710.14 CRJ87059.1 - 0.002 16.8 0.2 0.0031 16.2 0.2 1.1 1 0 0 1 1 1 1 Pellino zf-RING_5 PF14634.6 CRJ87059.1 - 0.0036 17.2 1.2 0.0036 17.2 1.2 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 CRJ87059.1 - 0.0051 17.1 0.4 0.0051 17.1 0.4 2.4 3 0 0 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.6 CRJ87059.1 - 0.027 14.5 0.4 0.027 14.5 0.4 2.0 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CRJ87059.1 - 0.04 13.8 1.3 0.04 13.8 1.3 2.5 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CRJ87059.1 - 1.7 8.5 9.0 0.054 13.4 2.0 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CRJ87059.1 - 1.8 8.5 9.9 0.93 9.4 4.8 3.1 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) BTB PF00651.31 CRJ87065.1 - 3.6e-06 27.2 0.0 1.2e-05 25.5 0.0 1.9 1 1 0 1 1 1 1 BTB/POZ domain zf-RING_5 PF14634.6 CRJ87074.1 - 2.7e-05 24.0 2.7 2.7e-05 24.0 2.7 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CRJ87074.1 - 0.00015 21.5 2.4 0.00015 21.5 2.4 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CRJ87074.1 - 0.0011 19.3 3.3 0.0011 19.3 3.3 2.7 3 0 0 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.6 CRJ87074.1 - 0.0011 18.9 5.9 0.0055 16.7 0.5 2.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-MIZ PF02891.20 CRJ87074.1 - 0.011 15.5 1.9 0.011 15.5 1.9 1.8 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger Prok-RING_4 PF14447.6 CRJ87074.1 - 0.011 15.6 5.7 0.011 15.6 5.7 3.0 4 0 0 4 4 4 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 CRJ87074.1 - 0.015 15.2 6.7 0.015 15.2 6.7 2.5 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CRJ87074.1 - 0.027 14.6 5.6 0.027 14.6 5.6 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING COesterase PF00135.28 CRJ87078.1 - 4.1e-60 204.1 0.0 7.2e-60 203.3 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Asp PF00026.23 CRJ87078.1 - 1.2e-29 103.7 0.0 3.1e-29 102.4 0.0 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease HsbA PF12296.8 CRJ87078.1 - 9.4e-15 55.1 0.1 2.6e-14 53.6 0.1 1.8 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Trypsin_2 PF13365.6 CRJ87078.1 - 4.2e-08 34.2 0.0 1.5e-07 32.4 0.0 2.0 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 CRJ87078.1 - 2.4e-05 24.3 0.0 6.5e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Trypsin TAXi_N PF14543.6 CRJ87078.1 - 0.00015 22.1 0.3 0.013 15.8 0.0 2.4 1 1 1 2 2 2 1 Xylanase inhibitor N-terminal Abhydrolase_6 PF12697.7 CRJ87078.1 - 0.0014 19.3 11.0 0.049 14.2 0.1 4.7 4 0 0 4 4 4 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 CRJ87078.1 - 0.0042 17.0 0.0 0.11 12.4 0.0 2.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CRJ87078.1 - 0.0071 15.6 0.0 1.9 7.7 0.0 2.5 2 0 0 2 2 2 2 Serine aminopeptidase, S33 PGAP1 PF07819.13 CRJ87078.1 - 0.061 13.0 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein LIDHydrolase PF10230.9 CRJ87078.1 - 0.09 12.3 0.0 0.29 10.6 0.0 1.8 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase TAXi_C PF14541.6 CRJ87078.1 - 0.16 11.7 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal MFS_1 PF07690.16 CRJ87105.1 - 3.2e-20 72.4 38.2 3.1e-19 69.1 38.2 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 CRJ87105.1 - 4.7e-07 28.6 21.3 1e-06 27.5 20.7 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Plasmid_stab_B PF10784.9 CRJ87105.1 - 0.032 14.1 0.0 0.086 12.7 0.0 1.7 1 0 0 1 1 1 0 Plasmid stability protein Glyco_hydro_10 PF00331.20 CRJ87122.1 - 9.2e-50 169.6 0.2 5.4e-31 107.9 0.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 10 NAD_binding_8 PF13450.6 CRJ87122.1 - 1e-12 48.1 0.9 2.1e-12 47.1 0.3 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CRJ87122.1 - 4.3e-07 29.8 1.0 1.1e-05 25.3 0.1 2.5 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CRJ87122.1 - 2.7e-06 26.8 0.0 6.8e-05 22.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CRJ87122.1 - 9.4e-06 26.1 0.1 0.17 12.5 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 CRJ87122.1 - 1.4e-05 24.6 0.1 0.0033 16.8 0.0 3.3 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 CRJ87122.1 - 6.1e-05 22.3 0.1 9.8e-05 21.6 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 CRJ87122.1 - 0.00027 20.9 0.0 0.0013 18.8 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.14 CRJ87122.1 - 0.00046 19.0 0.1 0.007 15.1 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.12 CRJ87122.1 - 0.00097 18.3 0.1 0.0022 17.1 0.0 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 CRJ87122.1 - 0.0011 18.3 0.0 0.023 14.0 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 CRJ87122.1 - 0.012 14.8 0.0 0.025 13.8 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.14 CRJ87122.1 - 0.024 13.5 0.2 0.067 12.0 0.0 1.8 2 0 0 2 2 2 0 Tryptophan halogenase FAD_oxidored PF12831.7 CRJ87122.1 - 0.08 12.3 0.2 0.28 10.5 0.0 2.1 3 0 0 3 3 3 0 FAD dependent oxidoreductase Shikimate_DH PF01488.20 CRJ87122.1 - 0.17 11.9 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase LolA_2 PF16584.5 CRJ87122.1 - 0.18 11.7 0.3 5.7 6.8 0.3 2.3 1 1 0 1 1 1 0 Outer membrane lipoprotein carrier protein LolA MFS_1 PF07690.16 CRJ87146.1 - 8.4e-14 51.2 1.7 1.1e-13 50.9 1.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3474 PF11960.8 CRJ87146.1 - 0.19 12.0 0.1 0.27 11.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) p450 PF00067.22 CRJ87160.1 - 1.3e-55 189.0 0.0 1.7e-55 188.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PFOR_II PF17147.4 CRJ87169.1 - 0.12 12.7 0.0 0.76 10.1 0.0 2.1 2 0 0 2 2 2 0 Pyruvate:ferredoxin oxidoreductase core domain II PH_10 PF15411.6 CRJ87184.1 - 3.8e-41 140.2 0.3 8.8e-41 139.0 0.3 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 CRJ87184.1 - 9.7e-30 104.2 0.2 1.7e-29 103.4 0.2 1.3 1 0 0 1 1 1 1 RhoGEF domain CDC24 PF06395.11 CRJ87184.1 - 3.6e-16 59.2 0.2 7.4e-16 58.2 0.2 1.5 1 0 0 1 1 1 1 CDC24 Calponin PB1 PF00564.24 CRJ87184.1 - 8.2e-09 35.3 0.0 1.9e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 PB1 domain DUF4071 PF13281.6 CRJ87184.1 - 0.087 11.9 2.0 0.4 9.7 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4071) WD40 PF00400.32 CRJ87193.1 - 3.9e-27 94.0 6.8 0.0003 21.5 0.0 7.5 7 0 0 7 7 7 5 WD domain, G-beta repeat F-box-like PF12937.7 CRJ87193.1 - 1.4e-13 50.5 1.7 8.6e-13 48.0 0.4 2.5 2 0 0 2 2 2 1 F-box-like ANAPC4_WD40 PF12894.7 CRJ87193.1 - 7.6e-08 32.5 0.1 0.14 12.4 0.0 3.7 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 CRJ87193.1 - 1.4e-06 28.0 0.1 3.5e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 CRJ87193.1 - 0.17 11.8 0.4 0.75 9.7 0.1 2.2 2 0 0 2 2 2 0 F-box LIN37 PF15306.6 CRJ87193.1 - 0.89 9.8 0.0 0.89 9.8 0.0 3.1 3 0 0 3 3 3 0 LIN37 Snf7 PF03357.21 CRJ87199.1 - 9.4e-44 149.0 12.0 1.1e-43 148.8 12.0 1.1 1 0 0 1 1 1 1 Snf7 YscO-like PF16789.5 CRJ87199.1 - 0.00096 19.2 6.0 0.0017 18.4 6.0 1.3 1 0 0 1 1 1 1 YscO-like protein MscS_porin PF12795.7 CRJ87199.1 - 0.0053 16.3 10.5 0.65 9.5 5.0 2.3 1 1 1 2 2 2 2 Mechanosensitive ion channel porin domain CLZ PF16526.5 CRJ87199.1 - 0.0067 16.8 7.9 0.22 11.9 0.0 3.5 2 1 1 3 3 3 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels NPV_P10 PF05531.12 CRJ87199.1 - 0.012 16.0 9.3 0.6 10.6 0.1 3.0 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Atg14 PF10186.9 CRJ87199.1 - 0.013 14.6 6.0 0.017 14.2 6.0 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Alpha-2-MRAP_C PF06401.11 CRJ87199.1 - 0.019 15.0 4.6 0.056 13.4 4.1 1.8 1 1 1 2 2 2 0 Alpha-2-macroglobulin RAP, C-terminal domain FlaC_arch PF05377.11 CRJ87199.1 - 0.043 14.2 6.8 2 8.9 0.0 3.5 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) FapA PF03961.13 CRJ87199.1 - 0.046 12.3 7.0 0.11 11.1 5.1 1.8 1 1 1 2 2 2 0 Flagellar Assembly Protein A DUF2205 PF10224.9 CRJ87199.1 - 0.071 13.1 6.1 0.9 9.6 2.7 3.1 2 1 1 3 3 3 0 Short coiled-coil protein Prefoldin PF02996.17 CRJ87199.1 - 0.21 11.5 9.1 1.9 8.5 0.1 3.5 3 1 0 3 3 3 0 Prefoldin subunit TMF_DNA_bd PF12329.8 CRJ87199.1 - 0.41 10.7 10.4 3 7.9 0.3 3.0 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding ADIP PF11559.8 CRJ87199.1 - 0.42 10.7 10.1 7.6 6.6 0.7 2.5 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Endotoxin_N PF03945.14 CRJ87199.1 - 0.46 10.2 4.5 1.5 8.5 0.1 2.1 1 1 1 2 2 2 0 delta endotoxin, N-terminal domain DUF848 PF05852.11 CRJ87199.1 - 0.52 10.4 6.5 0.46 10.6 4.4 2.0 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF4407 PF14362.6 CRJ87199.1 - 0.61 9.4 8.4 0.98 8.7 8.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) GrpE PF01025.19 CRJ87199.1 - 0.77 9.4 10.1 1.9 8.1 8.2 2.3 1 1 1 2 2 2 0 GrpE Spc7 PF08317.11 CRJ87199.1 - 0.93 8.3 12.5 1.5 7.6 11.5 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein bZIP_1 PF00170.21 CRJ87199.1 - 0.98 9.6 6.8 2.7 8.2 0.1 3.3 2 1 1 3 3 3 0 bZIP transcription factor Mod_r PF07200.13 CRJ87199.1 - 1.1 9.4 11.6 0.81 9.8 8.3 2.0 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DASH_Dam1 PF08653.10 CRJ87199.1 - 2 8.3 6.4 13 5.7 0.1 3.4 3 1 0 3 3 3 0 DASH complex subunit Dam1 Muted PF14942.6 CRJ87199.1 - 2.3 8.6 9.8 4.8 7.5 6.7 2.2 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein FUSC PF04632.12 CRJ87199.1 - 3.7 6.0 5.1 2.8 6.4 1.6 1.8 1 1 1 2 2 2 0 Fusaric acid resistance protein family DUF4446 PF14584.6 CRJ87199.1 - 4.4 7.3 8.5 7.4 6.6 2.5 2.5 1 1 3 4 4 4 0 Protein of unknown function (DUF4446) TMPIT PF07851.13 CRJ87199.1 - 7.1 5.8 8.7 6.6 5.9 7.0 1.6 1 1 1 2 2 2 0 TMPIT-like protein CCDC-167 PF15188.6 CRJ87199.1 - 9.7 6.6 9.7 12 6.3 3.1 3.2 1 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 Beta-lactamase PF00144.24 CRJ87212.1 - 2e-47 162.1 1.3 3.5e-47 161.2 1.3 1.3 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 CRJ87212.1 - 0.035 13.7 0.0 0.55 9.8 0.0 2.4 2 1 0 2 2 2 0 Beta-lactamase enzyme family Glycos_transf_1 PF00534.20 CRJ87220.1 - 3.1e-22 78.9 0.0 5.8e-22 78.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CRJ87220.1 - 1.4e-13 51.5 0.0 2e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 CRJ87220.1 - 0.0036 17.7 0.0 0.013 15.9 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_20 PF00982.21 CRJ87220.1 - 0.19 10.3 0.0 0.32 9.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 20 adh_short PF00106.25 CRJ87223.1 - 7.5e-14 51.6 0.0 3.9e-12 46.0 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CRJ87223.1 - 4.7e-05 23.0 0.0 0.00013 21.7 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRJ87223.1 - 0.027 14.4 0.0 0.036 14.0 0.0 1.3 1 0 0 1 1 1 0 KR domain HR1 PF02185.16 CRJ87223.1 - 0.088 12.9 0.1 4.2 7.6 0.0 3.0 3 1 0 3 3 3 0 Hr1 repeat EGF_2 PF07974.13 CRJ87229.1 - 0.00066 20.0 13.6 0.0012 19.2 13.6 1.4 1 0 0 1 1 1 1 EGF-like domain DNA_pol_A_exo1 PF01612.20 CRJ87231.1 - 0.077 12.7 0.1 0.17 11.6 0.0 1.6 2 0 0 2 2 2 0 3'-5' exonuclease PH PF00169.29 CRJ87234.1 - 1.5e-12 47.9 0.0 3e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 CRJ87234.1 - 0.013 15.8 0.0 0.12 12.6 0.0 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain Syja_N PF02383.18 CRJ87237.1 - 4.3e-88 295.7 0.0 5.4e-88 295.4 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain ADH_zinc_N PF00107.26 CRJ87242.1 - 1.3e-11 44.6 0.0 2.2e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CRJ87242.1 - 0.00026 20.8 0.3 0.0027 17.6 0.1 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Acetyltransf_8 PF13523.6 CRJ87251.1 - 3.2e-39 133.9 0.1 4.9e-39 133.3 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Glyco_hydro_11 PF00457.17 CRJ87258.1 - 3.3e-78 261.4 23.6 6.3e-78 260.5 23.6 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 MCU PF04678.13 CRJ87258.1 - 5.8e-23 81.9 1.0 5.8e-23 81.9 1.0 1.8 2 0 0 2 2 2 1 Mitochondrial calcium uniporter DUF1281 PF06924.11 CRJ87258.1 - 0.078 12.5 0.4 0.14 11.6 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1281) DUF3292 PF11696.8 CRJ87265.1 - 1e-270 899.8 0.0 1.2e-270 899.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) Pex24p PF06398.11 CRJ87265.1 - 0.03 13.3 0.0 0.046 12.7 0.0 1.3 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Glyco_hydro_32N PF00251.20 CRJ87272.1 - 1.9e-33 116.3 5.1 1.8e-22 80.3 3.2 2.4 2 1 0 2 2 2 2 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 CRJ87272.1 - 6e-30 104.3 0.2 9.1e-30 103.7 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal DUF4975 PF16346.5 CRJ87272.1 - 0.01 15.9 0.0 0.033 14.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4975) PNP_UDP_1 PF01048.20 CRJ87279.1 - 3e-10 39.7 0.1 1.1e-09 38.0 0.1 1.8 1 1 0 1 1 1 1 Phosphorylase superfamily E1_dh PF00676.20 CRJ87388.1 - 2.2e-11 43.3 0.0 2.7e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DUF1771 PF08590.10 CRJ87568.1 - 1.7e-10 41.1 5.5 2.8e-10 40.4 5.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) DUF99 PF01949.16 CRJ87568.1 - 0.0077 15.7 0.1 0.0093 15.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF99 Smr PF01713.21 CRJ87568.1 - 0.02 15.2 2.3 0.47 10.8 0.7 2.6 2 1 0 2 2 2 0 Smr domain DUF2448 PF10476.9 CRJ87568.1 - 0.1 12.5 0.1 0.11 12.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2448) Caldesmon PF02029.15 CRJ87644.1 - 0.026 13.3 4.1 0.029 13.1 4.1 1.0 1 0 0 1 1 1 0 Caldesmon AA_permease_2 PF13520.6 CRJ88076.1 - 1.4e-13 50.5 12.7 1.5e-13 50.4 12.7 1.0 1 0 0 1 1 1 1 Amino acid permease Aa_trans PF01490.18 CRJ88246.1 - 3.9e-18 65.4 13.2 4.8e-18 65.1 13.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein ABC_tran PF00005.27 CRJ88254.1 - 2.8e-48 163.9 0.1 2.8e-24 86.2 0.0 3.8 2 2 0 2 2 2 2 ABC transporter 4HB PF17947.1 CRJ88254.1 - 3.1e-29 100.8 0.3 3.1e-29 100.8 0.3 2.5 2 0 0 2 2 1 1 Four helical bundle domain AAA_21 PF13304.6 CRJ88254.1 - 7.2e-18 65.4 0.0 0.00082 19.3 0.0 5.1 4 1 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CRJ88254.1 - 9.9e-16 57.8 0.1 2.1e-05 24.1 0.0 4.1 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CRJ88254.1 - 3.7e-10 40.7 3.2 0.00011 22.8 0.1 2.9 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.6 CRJ88254.1 - 9.2e-09 34.9 0.0 0.0062 16.2 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CRJ88254.1 - 1.7e-08 34.6 0.0 0.00018 21.5 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 CRJ88254.1 - 2.9e-07 30.6 0.0 0.0021 18.1 0.0 3.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 CRJ88254.1 - 1.9e-06 28.2 0.0 0.034 14.4 0.0 3.4 3 0 0 3 3 2 2 AAA domain AAA_28 PF13521.6 CRJ88254.1 - 2.7e-06 27.7 0.0 0.025 14.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.23 CRJ88254.1 - 6.3e-06 26.3 0.0 0.00054 20.1 0.0 3.1 3 0 0 3 3 3 1 Dynamin family AAA_18 PF13238.6 CRJ88254.1 - 8.2e-06 26.4 0.0 0.18 12.4 0.0 3.4 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 CRJ88254.1 - 1e-05 25.4 1.9 0.047 13.4 0.0 3.3 2 2 1 3 3 3 2 AAA ATPase domain AAA_16 PF13191.6 CRJ88254.1 - 2.3e-05 24.8 0.0 0.25 11.7 0.0 3.4 3 0 0 3 3 2 2 AAA ATPase domain MeaB PF03308.16 CRJ88254.1 - 4.9e-05 22.4 0.1 0.24 10.4 0.1 2.5 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 CRJ88254.1 - 5.1e-05 23.5 0.0 0.68 10.1 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 CRJ88254.1 - 6.2e-05 23.4 0.0 1.3 9.5 0.0 4.0 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 CRJ88254.1 - 0.0001 22.7 0.0 0.76 10.2 0.0 2.9 2 0 0 2 2 2 2 RNA helicase PduV-EutP PF10662.9 CRJ88254.1 - 0.0001 22.0 0.0 0.059 13.1 0.0 2.7 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_27 PF13514.6 CRJ88254.1 - 0.00021 21.0 0.0 0.15 11.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 CRJ88254.1 - 0.00024 20.9 0.0 0.93 9.2 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 CRJ88254.1 - 0.00074 19.3 0.0 3.5 7.3 0.0 3.4 3 0 0 3 3 3 0 AAA domain G-alpha PF00503.20 CRJ88254.1 - 0.00091 18.5 0.0 1.4 8.0 0.0 2.6 3 0 0 3 3 3 2 G-protein alpha subunit NACHT PF05729.12 CRJ88254.1 - 0.0011 18.9 0.0 0.36 10.7 0.0 2.5 2 0 0 2 2 2 1 NACHT domain Rad17 PF03215.15 CRJ88254.1 - 0.0026 17.7 0.0 1.4 8.8 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain DUF87 PF01935.17 CRJ88254.1 - 0.0026 17.9 0.1 0.94 9.5 0.0 3.4 3 0 0 3 3 3 1 Helicase HerA, central domain HEAT PF02985.22 CRJ88254.1 - 0.0041 17.2 0.7 22 5.7 0.0 4.3 3 0 0 3 3 3 0 HEAT repeat SbcCD_C PF13558.6 CRJ88254.1 - 0.0042 17.3 0.0 1.3 9.3 0.0 3.2 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Septin PF00735.18 CRJ88254.1 - 0.0057 16.0 0.6 2.7 7.2 0.0 3.2 3 0 0 3 3 3 1 Septin cobW PF02492.19 CRJ88254.1 - 0.0061 16.2 0.1 7.3 6.1 0.0 3.3 4 0 0 4 4 3 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 CRJ88254.1 - 0.0071 16.6 0.0 9.3 6.5 0.0 3.3 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 CRJ88254.1 - 0.0073 16.3 0.0 7.2 6.7 0.0 3.1 3 0 0 3 3 2 0 AAA domain PRK PF00485.18 CRJ88254.1 - 0.0075 16.0 0.0 0.34 10.6 0.0 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family ATPase_2 PF01637.18 CRJ88254.1 - 0.016 15.1 0.1 6 6.7 0.0 3.0 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea ATP_bind_1 PF03029.17 CRJ88254.1 - 0.02 14.7 0.0 7.2 6.3 0.0 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NB-ARC PF00931.22 CRJ88254.1 - 0.027 13.6 0.0 1.8 7.6 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain IstB_IS21 PF01695.17 CRJ88254.1 - 0.028 14.1 0.0 7.6 6.2 0.0 2.7 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_7 PF12775.7 CRJ88254.1 - 0.034 13.7 0.0 5.9 6.4 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Cytidylate_kin PF02224.18 CRJ88254.1 - 0.035 13.8 0.0 7.4 6.2 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase CLP1_P PF16575.5 CRJ88254.1 - 0.037 13.8 0.0 1.8 8.3 0.0 2.6 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop HEAT_2 PF13646.6 CRJ88254.1 - 0.041 14.3 4.3 2.5 8.5 2.2 3.6 2 1 2 4 4 3 0 HEAT repeats MukB PF04310.12 CRJ88254.1 - 0.05 13.4 0.0 9.2 6.0 0.0 2.4 2 0 0 2 2 2 0 MukB N-terminal AAA_13 PF13166.6 CRJ88254.1 - 0.066 11.9 4.2 2.4 6.7 0.0 3.9 4 1 1 5 5 4 0 AAA domain T2SSE PF00437.20 CRJ88254.1 - 0.076 12.1 0.1 3.5 6.6 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein ParcG PF10274.9 CRJ88254.1 - 0.083 13.0 0.5 2.5 8.2 0.2 2.9 1 1 2 3 3 3 0 Parkin co-regulated protein Mg_chelatase PF01078.21 CRJ88254.1 - 0.09 12.1 0.0 4.1 6.7 0.0 2.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Rif1_N PF12231.8 CRJ88254.1 - 0.091 11.7 0.6 0.15 11.0 0.1 1.5 2 0 0 2 2 1 0 Rap1-interacting factor 1 N terminal NTPase_1 PF03266.15 CRJ88254.1 - 0.094 12.6 0.0 18 5.2 0.1 2.9 2 0 0 2 2 2 0 NTPase Zeta_toxin PF06414.12 CRJ88254.1 - 0.094 12.0 0.0 17 4.6 0.0 2.7 2 0 0 2 2 2 0 Zeta toxin Ploopntkinase3 PF18751.1 CRJ88254.1 - 0.11 12.5 0.0 20 5.0 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 DAP3 PF10236.9 CRJ88254.1 - 1.5 7.9 3.4 22 4.1 0.2 2.7 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 HEAT_EZ PF13513.6 CRJ88254.1 - 8.1 7.1 10.7 11 6.6 1.4 5.0 6 0 0 6 6 3 0 HEAT-like repeat His_Phos_1 PF00300.22 CRJ88263.1 - 7e-14 52.0 0.0 1.5e-12 47.6 0.0 2.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF4795 PF16043.5 CRJ88263.1 - 0.036 13.7 0.3 0.64 9.6 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) Macro PF01661.21 CRJ88268.1 - 3.8e-38 130.2 0.2 6.1e-38 129.5 0.2 1.3 1 0 0 1 1 1 1 Macro domain tRNA-synt_1c PF00749.21 CRJ88276.1 - 6.1e-85 284.9 0.2 1.2e-83 280.6 0.2 2.2 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 CRJ88276.1 - 1e-33 116.6 0.0 7.9e-33 113.8 0.0 2.4 3 0 0 3 3 3 1 tRNA synthetases class I (E and Q), anti-codon binding domain DUF3433 PF11915.8 CRJ88287.1 - 1.6e-29 102.2 22.9 7.9e-18 64.7 5.3 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) CFEM PF05730.11 CRJ88292.1 - 6.7e-11 42.1 5.7 1e-10 41.6 5.7 1.3 1 0 0 1 1 1 1 CFEM domain Cupin_2 PF07883.11 CRJ88300.1 - 6.6e-05 22.5 0.0 9.6e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 CRJ88300.1 - 0.00028 20.5 0.0 0.00038 20.1 0.0 1.3 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 CRJ88300.1 - 0.055 13.2 0.0 0.097 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) CBM_1 PF00734.18 CRJ88307.1 - 1.9e-09 37.3 15.8 1.9e-09 37.3 15.8 2.8 2 0 0 2 2 2 1 Fungal cellulose binding domain Glyco_hydro_3_C PF01915.22 CRJ88315.1 - 1.6e-50 171.9 0.1 2.3e-50 171.4 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 CRJ88315.1 - 2.3e-24 86.4 0.0 8.6e-24 84.5 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 CRJ88315.1 - 9.9e-22 76.8 0.0 1.8e-21 76.0 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Shisa PF13908.6 CRJ88321.1 - 0.029 14.6 0.0 0.033 14.5 0.0 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator CYYR1 PF10873.8 CRJ88321.1 - 0.039 14.4 1.2 0.06 13.8 1.2 1.3 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 EphA2_TM PF14575.6 CRJ88321.1 - 0.087 13.7 0.0 0.11 13.4 0.0 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DAG1 PF05454.11 CRJ88321.1 - 0.23 10.8 0.1 0.28 10.5 0.1 1.1 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) GMC_oxred_N PF00732.19 CRJ88327.1 - 2.8e-68 230.5 0.0 4e-68 230.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase TRI12 PF06609.13 CRJ88327.1 - 3.7e-55 187.5 17.6 5e-55 187.1 17.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) GMC_oxred_C PF05199.13 CRJ88327.1 - 1.3e-39 136.0 0.0 2.2e-39 135.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase MFS_1 PF07690.16 CRJ88327.1 - 1.5e-25 89.8 52.5 5.2e-25 88.1 49.6 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily DAO PF01266.24 CRJ88327.1 - 0.00015 21.5 1.0 0.0015 18.2 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CRJ88327.1 - 0.0018 18.5 0.4 0.0059 16.8 0.4 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DUF3522 PF12036.8 CRJ88327.1 - 0.0035 17.7 0.4 0.012 15.9 0.4 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) FAD_binding_2 PF00890.24 CRJ88327.1 - 0.0092 15.1 0.1 0.019 14.1 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 CRJ88327.1 - 0.0092 15.1 0.1 0.028 13.5 0.1 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 CRJ88327.1 - 0.025 13.8 0.5 0.07 12.3 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lyase_1 PF00206.20 CRJ88339.1 - 1.2e-51 176.0 0.1 4.1e-51 174.2 0.1 1.7 1 1 0 1 1 1 1 Lyase ADSL_C PF10397.9 CRJ88339.1 - 1.5e-19 70.3 0.0 1.3e-18 67.3 0.0 2.4 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus HgmA PF04209.13 CRJ88347.1 - 1.2e-128 429.5 0.0 1.3e-128 429.3 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Arg_decarb_HB PF17810.1 CRJ88347.1 - 0.063 13.5 0.0 0.43 10.9 0.0 2.2 2 0 0 2 2 2 0 Arginine decarboxylase helical bundle domain Fungal_trans PF04082.18 CRJ88357.1 - 4.9e-11 42.2 0.0 8.5e-11 41.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 CRJ88357.1 - 0.00013 22.2 3.2 0.0011 19.4 0.6 2.5 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.26 CRJ88357.1 - 0.0016 18.8 0.7 0.0035 17.7 0.7 1.6 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-met PF12874.7 CRJ88357.1 - 0.0032 17.8 0.1 0.0065 16.8 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CRJ88357.1 - 0.023 15.0 0.0 0.043 14.1 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 CRJ88357.1 - 0.027 15.3 0.3 0.061 14.2 0.3 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger DUF4632 PF15451.6 CRJ88357.1 - 7.5 6.7 6.1 22 5.2 6.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) Thiolase_N PF00108.23 CRJ88365.1 - 2.6e-58 197.4 0.1 1e-57 195.4 0.1 1.9 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CRJ88365.1 - 1.8e-38 131.0 0.0 2.6e-38 130.4 0.0 1.3 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 CRJ88365.1 - 0.0077 15.8 0.1 0.02 14.5 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Prolactin_RP PF15172.6 CRJ88365.1 - 0.016 14.8 0.9 0.035 13.7 0.1 2.0 2 0 0 2 2 2 0 Prolactin-releasing peptide Fe-ADH PF00465.19 CRJ88376.1 - 1.8e-65 221.1 0.0 2.4e-65 220.7 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 CRJ88376.1 - 6.1e-10 39.2 0.0 0.00033 20.4 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase CoA_trans PF01144.23 CRJ88382.1 - 8.3e-98 326.1 4.0 1.1e-63 214.5 1.2 2.1 2 0 0 2 2 2 2 Coenzyme A transferase Mal_decarbox_Al PF16957.5 CRJ88382.1 - 0.011 14.1 0.1 0.1 10.9 0.1 2.0 2 0 0 2 2 2 0 Malonate decarboxylase, alpha subunit, transporter CoA_transf_3 PF02515.17 CRJ88397.1 - 4.8e-90 302.3 0.0 6.6e-90 301.9 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III Aspzincin_M35 PF14521.6 CRJ88405.1 - 3.8e-05 24.3 0.1 9.1e-05 23.0 0.0 1.6 2 0 0 2 2 2 1 Lysine-specific metallo-endopeptidase Shigella_OspC PF06128.11 CRJ88413.1 - 0.26 11.0 0.0 0.42 10.3 0.0 1.2 1 0 0 1 1 1 0 Shigella flexneri OspC protein Pec_lyase_C PF00544.19 CRJ88423.1 - 1.5e-12 47.5 6.2 8.5e-11 41.8 6.2 2.2 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 CRJ88423.1 - 5.3e-06 26.4 7.0 0.0036 17.2 0.6 2.4 1 1 1 2 2 2 2 Right handed beta helix region Imm41 PF15592.6 CRJ88423.1 - 0.14 12.5 0.0 0.31 11.4 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 41 Glyco_hydro_61 PF03443.14 CRJ88441.1 - 7.5e-44 150.1 0.0 1.7e-43 148.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Pyr_redox_2 PF07992.14 CRJ88441.1 - 2.5e-11 43.4 0.0 4.8e-08 32.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 CRJ88441.1 - 1.9e-07 29.9 0.1 9.1e-07 27.7 0.1 2.1 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 CRJ88441.1 - 2.1e-07 30.4 0.0 0.0011 18.2 0.0 3.3 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 CRJ88441.1 - 1.6e-05 24.3 0.0 0.0046 16.3 0.0 3.0 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CRJ88441.1 - 2.1e-05 24.6 0.0 5.3e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 CRJ88441.1 - 0.00014 21.8 0.0 0.0031 17.5 0.0 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 CRJ88441.1 - 0.0041 16.8 0.0 3.2 7.3 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase LBR_tudor PF09465.10 CRJ88441.1 - 0.026 14.3 0.5 0.083 12.7 0.1 2.1 2 0 0 2 2 2 0 Lamin-B receptor of TUDOR domain FAD_binding_2 PF00890.24 CRJ88441.1 - 0.043 12.9 0.0 0.29 10.2 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 CRJ88441.1 - 0.088 11.5 0.0 0.27 9.9 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein Fip1 PF05182.13 CRJ88459.1 - 3e-20 71.5 0.9 5.3e-20 70.7 0.9 1.4 1 0 0 1 1 1 1 Fip1 motif Nucleoporin_FG PF13634.6 CRJ88465.1 - 1.7e-10 41.6 81.3 0.0003 21.6 43.2 3.3 1 1 2 3 3 3 3 Nucleoporin FG repeat region PMEI PF04043.15 CRJ88465.1 - 0.15 12.4 0.4 0.35 11.2 0.1 1.8 2 0 0 2 2 2 0 Plant invertase/pectin methylesterase inhibitor DUF241 PF03087.14 CRJ88465.1 - 0.15 11.8 0.3 0.29 11.0 0.3 1.4 1 0 0 1 1 1 0 Arabidopsis protein of unknown function Tup_N PF08581.10 CRJ88465.1 - 0.96 9.8 3.4 0.76 10.1 0.1 2.3 3 0 0 3 3 3 0 Tup N-terminal FAM184 PF15665.5 CRJ88465.1 - 1.2 8.9 5.0 11 5.7 5.0 2.2 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B RNA_pol_3_Rpc31 PF11705.8 CRJ88472.1 - 3.3e-60 204.2 3.7 4.4e-60 203.7 3.7 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 2-oxoacid_dh PF00198.23 CRJ88484.1 - 3.5e-51 173.9 0.1 5.6e-51 173.2 0.1 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 CRJ88484.1 - 3.9e-18 65.0 1.1 8.9e-18 63.9 1.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 CRJ88484.1 - 1.3e-09 38.3 1.6 3.9e-09 36.7 1.6 1.9 1 0 0 1 1 1 1 e3 binding domain DUF3614 PF12267.8 CRJ88484.1 - 0.027 15.0 0.5 0.054 14.0 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3614) Nop16 PF09420.10 CRJ88484.1 - 0.097 12.7 0.6 0.15 12.1 0.6 1.2 1 0 0 1 1 1 0 Ribosome biogenesis protein Nop16 HpcH_HpaI PF03328.14 CRJ88496.1 - 5.5e-29 100.9 0.3 4.3e-21 75.1 0.0 2.1 1 1 1 2 2 2 2 HpcH/HpaI aldolase/citrate lyase family Sec7 PF01369.20 CRJ88502.1 - 1.2e-71 240.2 5.1 3.5e-71 238.7 1.0 3.1 3 0 0 3 3 3 1 Sec7 domain Sec7_N PF12783.7 CRJ88502.1 - 7.4e-37 126.7 1.2 7.4e-37 126.7 1.2 3.1 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 CRJ88502.1 - 5.8e-35 119.0 10.7 4.2e-33 113.0 0.2 5.7 7 0 0 7 7 7 2 Domain of unknown function (DUF1981) DCB PF16213.5 CRJ88502.1 - 4.1e-22 78.7 1.1 3.8e-21 75.5 0.0 2.9 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 TetR_C_29 PF17938.1 CRJ88502.1 - 0.1 12.7 0.3 0.53 10.4 0.0 2.4 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain MIOX PF05153.15 CRJ88508.1 - 2.6e-114 381.0 0.0 3.1e-114 380.7 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol oxygenase HDOD PF08668.12 CRJ88508.1 - 0.04 13.4 0.0 0.12 11.9 0.0 1.7 1 1 1 2 2 2 0 HDOD domain HD PF01966.22 CRJ88508.1 - 0.044 14.0 0.0 0.88 9.8 0.0 2.2 2 0 0 2 2 2 0 HD domain Sugar_tr PF00083.24 CRJ88514.1 - 3.9e-67 227.1 14.4 4.7e-67 226.8 14.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRJ88514.1 - 4.3e-17 62.1 16.2 5.8e-17 61.6 16.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 CRJ88514.1 - 0.00046 19.2 4.3 0.00046 19.2 4.3 2.1 2 0 0 2 2 2 2 MFS_1 like family Fungal_trans_2 PF11951.8 CRJ88520.1 - 8e-07 28.2 0.8 1.3e-06 27.5 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Pkinase_Tyr PF07714.17 CRJ88525.1 - 0.059 12.6 0.0 0.067 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.25 CRJ88525.1 - 0.099 12.0 0.0 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain LysM PF01476.20 CRJ88529.1 - 4e-33 113.2 0.0 4.7e-05 23.4 0.0 6.4 6 0 0 6 6 6 6 LysM domain HTH_23 PF13384.6 CRJ88529.1 - 0.0063 16.3 0.0 56 3.7 0.0 4.2 4 0 0 4 4 4 0 Homeodomain-like domain LRV_FeS PF05484.11 CRJ88529.1 - 0.047 13.7 0.0 6.8 6.8 0.0 4.1 5 0 0 5 5 5 0 LRV protein FeS4 cluster NDUFB11 PF17250.2 CRJ88529.1 - 0.15 12.7 0.0 1.1e+02 3.6 0.0 3.8 4 0 0 4 4 4 0 NADH-ubiquinone oxidoreductase 11 kDa subunit Inositol_P PF00459.25 CRJ88537.1 - 3.9e-74 249.6 0.0 4.4e-74 249.4 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family DHquinase_II PF01220.19 CRJ88551.1 - 1.1e-62 209.7 0.2 1.4e-62 209.4 0.2 1.1 1 0 0 1 1 1 1 Dehydroquinase class II AP_endonuc_2 PF01261.24 CRJ88556.1 - 4.2e-29 101.5 1.3 5.4e-29 101.1 1.3 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Shikimate_dh_N PF08501.11 CRJ88563.1 - 3.4e-22 78.5 0.0 8e-22 77.3 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 CRJ88563.1 - 1e-05 25.2 0.2 2.5e-05 23.9 0.2 1.7 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 CRJ88563.1 - 0.05 13.7 0.1 0.087 12.9 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sugar_tr PF00083.24 CRJ88568.1 - 3.3e-103 346.0 10.2 3.7e-103 345.8 10.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRJ88568.1 - 4.6e-09 35.7 30.2 4.7e-06 25.8 3.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily RDD PF06271.12 CRJ88568.1 - 5.9 7.1 13.3 0.3 11.3 4.7 2.4 1 1 1 2 2 2 0 RDD family Fungal_trans PF04082.18 CRJ88576.1 - 1.7e-09 37.1 0.0 2.7e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRJ88576.1 - 3.5e-08 33.4 9.0 6.6e-08 32.5 9.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pex14_N PF04695.13 CRJ88576.1 - 0.076 13.7 5.9 1.7 9.3 4.2 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Shikimate_dh_N PF08501.11 CRJ88584.1 - 4.8e-21 74.8 0.0 1.1e-20 73.6 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain DHquinase_I PF01487.15 CRJ88584.1 - 5.5e-21 75.9 0.0 8.7e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 CRJ88584.1 - 6.9e-11 42.5 0.1 1.4e-10 41.5 0.1 1.5 1 0 0 1 1 1 1 Shikimate kinase SDH_C PF18317.1 CRJ88584.1 - 7.1e-10 38.5 0.2 1.4e-09 37.5 0.2 1.6 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 CRJ88584.1 - 1.7e-06 28.1 0.0 3.7e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_16 PF13191.6 CRJ88584.1 - 0.014 15.7 0.3 0.17 12.2 0.1 2.7 3 0 0 3 3 3 0 AAA ATPase domain AAA_25 PF13481.6 CRJ88584.1 - 0.019 14.6 0.0 0.041 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain F420_oxidored PF03807.17 CRJ88584.1 - 0.069 13.7 0.0 0.18 12.4 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 CRJ88584.1 - 0.069 13.4 0.0 0.21 11.9 0.0 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_4 PF07993.12 CRJ88599.1 - 0.037 13.2 0.1 0.062 12.4 0.0 1.4 1 1 0 1 1 1 0 Male sterility protein Epimerase PF01370.21 CRJ88599.1 - 0.045 13.2 0.0 0.063 12.7 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family MFS_1 PF07690.16 CRJ88605.1 - 1.6e-10 40.5 45.5 1.9e-10 40.2 40.6 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily TetR_C_34 PF17929.1 CRJ88605.1 - 0.13 12.3 0.0 0.43 10.7 0.0 1.8 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DUF4293 PF14126.6 CRJ88605.1 - 8.5 6.6 10.0 26 5.0 5.2 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF4293) UDPGT PF00201.18 CRJ88612.1 - 2.3e-17 63.0 0.0 5.9e-17 61.6 0.0 1.6 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_transf_28 PF03033.20 CRJ88612.1 - 0.00019 21.5 0.0 0.00034 20.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Glyco_tran_28_C PF04101.16 CRJ88612.1 - 0.00025 21.1 0.0 0.0004 20.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.6 CRJ88612.1 - 0.0027 17.0 0.9 0.12 11.6 0.0 2.7 2 1 0 2 2 2 1 Glycosyl transferase family 1 Glyco_transf_4 PF13439.6 CRJ88612.1 - 0.0086 16.1 0.4 0.03 14.3 0.1 2.0 2 0 0 2 2 2 1 Glycosyltransferase Family 4 FrhB_FdhB_N PF04422.13 CRJ88612.1 - 0.15 12.2 0.0 0.36 11.0 0.0 1.6 1 0 0 1 1 1 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term Peptidase_M15_4 PF13539.6 CRJ88618.1 - 0.016 15.7 0.1 0.03 14.8 0.1 1.5 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase UPF0175 PF03683.13 CRJ88618.1 - 0.21 11.3 0.0 0.35 10.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0175) Sugar_tr PF00083.24 CRJ88635.1 - 2.4e-120 402.4 19.0 2.8e-120 402.2 19.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRJ88635.1 - 1.4e-21 76.8 34.8 2.4e-13 49.7 14.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily NAD_binding_4 PF07993.12 CRJ88652.1 - 2.5e-38 131.7 0.0 5.4e-38 130.6 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 CRJ88652.1 - 3.8e-34 118.0 0.0 5.5e-34 117.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 CRJ88652.1 - 1.6e-08 34.3 0.0 5.3e-08 32.6 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 CRJ88652.1 - 0.00061 20.1 0.1 0.0016 18.7 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 CRJ88652.1 - 0.00092 18.3 0.0 0.037 13.0 0.0 2.2 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 CRJ88652.1 - 0.075 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 KR domain NAD_binding_10 PF13460.6 CRJ88652.1 - 0.078 12.9 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 NAD(P)H-binding AMP-binding PF00501.28 CRJ88658.1 - 7.4e-16 57.8 0.1 3e-15 55.7 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme HD_6 PF18019.1 CRJ88658.1 - 0.0026 17.9 0.4 0.004 17.3 0.4 1.4 1 0 0 1 1 1 1 HD domain Glycos_transf_1 PF00534.20 CRJ88658.1 - 0.15 11.6 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferases group 1 NUDIX_4 PF14815.6 CRJ88658.1 - 0.16 11.9 0.2 1.8 8.6 0.0 2.3 2 0 0 2 2 2 0 NUDIX domain Pyridoxal_deC PF00282.19 CRJ88661.1 - 1.4e-47 162.2 0.0 2e-47 161.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DUF4396 PF14342.6 CRJ88661.1 - 7.8e-45 152.7 3.1 1.6e-44 151.7 3.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4396) Aminotran_5 PF00266.19 CRJ88661.1 - 0.0034 16.4 0.0 0.0056 15.7 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V ABC2_membrane PF01061.24 CRJ88668.1 - 4.1e-13 49.3 6.1 4.1e-13 49.3 6.1 1.5 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 CRJ88668.1 - 5e-05 23.8 0.0 0.00017 22.1 0.0 1.9 2 0 0 2 2 2 1 ABC transporter PDR_CDR PF06422.12 CRJ88668.1 - 0.02 14.8 0.4 0.057 13.3 0.4 1.7 1 0 0 1 1 1 0 CDR ABC transporter PAH PF02671.21 CRJ88867.1 - 1.8e-09 37.6 0.1 2.9e-09 36.9 0.1 1.3 1 0 0 1 1 1 1 Paired amphipathic helix repeat DUF621 PF04789.15 CRJ89071.1 - 0.2 10.8 0.0 0.23 10.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF621) Thiamine_BP PF01910.17 CRJ89342.1 - 2.5e-20 72.2 0.2 2.7e-20 72.1 0.2 1.0 1 0 0 1 1 1 1 Thiamine-binding protein Baculo_F PF12259.8 CRJ89342.1 - 0.016 13.8 0.0 0.018 13.6 0.0 1.0 1 0 0 1 1 1 0 Baculovirus F protein Ykof PF07615.11 CRJ89342.1 - 0.13 12.8 0.0 0.15 12.5 0.0 1.1 1 0 0 1 1 1 0 YKOF-related Family STN PF07660.14 CRJ89342.1 - 0.21 11.4 0.0 1.1 9.1 0.0 2.0 1 1 1 2 2 2 0 Secretin and TonB N terminus short domain Acyl_transf_1 PF00698.21 CRJ89396.1 - 2.6e-18 66.6 0.0 3.3e-12 46.6 0.0 2.0 1 1 0 2 2 2 2 Acyl transferase domain FlgT_N PF16548.5 CRJ89396.1 - 0.056 14.0 0.3 0.17 12.5 0.1 1.8 2 0 0 2 2 2 0 Flagellar assembly protein T, N-terminal domain ROS_MUCR PF05443.11 CRJ89396.1 - 0.14 12.2 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 ROS/MUCR transcriptional regulator protein CPSF100_C PF13299.6 CRJ89495.1 - 1.7e-34 119.5 0.1 1.8e-34 119.4 0.1 1.0 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal TamB PF04357.13 CRJ89495.1 - 0.11 11.7 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 TamB, inner membrane protein subunit of TAM complex Acetyltransf_8 PF13523.6 CRJ89742.1 - 2.1e-47 160.5 3.1 2.3e-47 160.3 3.1 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 CRJ89742.1 - 0.0053 17.4 0.5 0.0088 16.7 0.5 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DNA_pol3_delta2 PF13177.6 CRJ89889.1 - 4.2e-10 39.6 0.1 8.1e-10 38.7 0.1 1.5 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_22 PF13401.6 CRJ89889.1 - 4.4e-07 30.3 0.1 7.1e-06 26.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 CRJ89889.1 - 1.5e-06 28.7 0.1 3.8e-06 27.4 0.1 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 CRJ89889.1 - 7.3e-05 23.1 0.1 0.00021 21.7 0.1 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_24 PF13479.6 CRJ89889.1 - 0.00026 20.8 0.7 0.0017 18.1 0.5 2.3 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CRJ89889.1 - 0.00069 20.0 1.2 0.0061 17.0 0.5 2.6 2 1 0 2 2 2 1 AAA ATPase domain Rad17 PF03215.15 CRJ89889.1 - 0.05 13.5 0.0 0.13 12.1 0.0 1.6 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_30 PF13604.6 CRJ89889.1 - 0.055 13.2 0.2 0.14 11.9 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 CRJ89889.1 - 0.064 13.3 0.6 0.25 11.3 0.6 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 CRJ89889.1 - 0.079 13.5 0.0 0.17 12.4 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 CRJ89889.1 - 0.095 12.9 0.1 0.18 11.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain T4SS-DNA_transf PF02534.14 CRJ89889.1 - 0.099 11.4 0.4 0.35 9.6 0.0 1.8 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer RFC1 PF08519.12 CRJ89910.1 - 2.2e-57 193.6 0.1 9.5e-57 191.6 0.0 2.0 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain AAA PF00004.29 CRJ89910.1 - 6.1e-06 26.7 0.1 0.00015 22.2 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.13 CRJ89910.1 - 0.0011 18.8 0.0 0.0025 17.6 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Ribosomal_L16 PF00252.18 CRJ89917.1 - 2e-31 108.7 0.6 2.9e-31 108.2 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e BRCT PF00533.26 CRJ89923.1 - 2.8e-15 56.4 0.0 6.7e-15 55.2 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 CRJ89923.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 twin BRCT domain Rep_fac_C PF08542.11 CRJ89928.1 - 4.4e-05 23.8 0.1 7.6e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 Replication factor C C-terminal domain DUF1882 PF08966.11 CRJ89928.1 - 0.099 12.9 0.2 0.3 11.4 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1882) AMP-binding PF00501.28 CRJ89935.1 - 1.9e-34 119.0 0.1 2.7e-34 118.5 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CRJ89935.1 - 1.1e-24 87.1 0.3 2.3e-24 86.2 0.3 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Reprolysin_5 PF13688.6 CRJ89948.1 - 3.4e-59 200.3 6.3 3.4e-59 200.3 6.3 2.5 3 1 0 3 3 3 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 CRJ89948.1 - 5.6e-50 169.9 2.1 1.1e-49 169.0 2.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 CRJ89948.1 - 6.6e-45 153.3 2.5 6.6e-45 153.3 2.5 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 CRJ89948.1 - 1.8e-16 60.7 32.3 1.8e-16 60.7 32.3 5.1 4 1 1 5 5 5 1 Disintegrin Reprolysin_3 PF13582.6 CRJ89948.1 - 2.5e-12 47.4 0.0 5.6e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like ADAM_CR_2 PF17771.1 CRJ89948.1 - 0.00046 20.6 14.4 0.00046 20.6 14.4 4.9 2 1 2 4 4 4 1 ADAM cysteine-rich domain Reprolysin PF01421.19 CRJ89948.1 - 0.0012 18.8 9.3 0.0012 18.8 9.3 3.2 2 1 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.19 CRJ89948.1 - 0.0084 16.3 0.1 0.02 15.1 0.1 1.6 1 0 0 1 1 1 1 Reprolysin family propeptide AMP-binding PF00501.28 CRJ89955.1 - 4.7e-35 121.0 0.2 7e-35 120.4 0.2 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CRJ89955.1 - 1e-24 87.3 0.3 2.2e-24 86.2 0.3 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Reprolysin_5 PF13688.6 CRJ89962.1 - 3.8e-53 180.6 7.4 6.6e-53 179.8 6.3 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 CRJ89962.1 - 4.1e-49 167.1 2.5 6e-49 166.6 2.5 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 CRJ89962.1 - 1.8e-39 135.5 3.4 1.8e-39 135.5 3.4 1.6 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 CRJ89962.1 - 1.2e-12 48.4 0.0 2.6e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 CRJ89962.1 - 0.00022 22.0 10.1 0.00022 22.0 10.1 2.8 2 0 0 2 2 2 1 Disintegrin Pep_M12B_propep PF01562.19 CRJ89962.1 - 0.0037 17.5 0.1 0.0071 16.6 0.1 1.4 1 0 0 1 1 1 1 Reprolysin family propeptide Reprolysin PF01421.19 CRJ89962.1 - 0.0058 16.6 9.9 0.0058 16.6 9.9 3.3 2 1 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease WD40 PF00400.32 CRJ89969.1 - 1.2e-14 54.5 5.9 0.011 16.5 0.1 6.6 6 0 0 6 6 6 4 WD domain, G-beta repeat LisH PF08513.11 CRJ89969.1 - 0.089 12.8 0.6 0.49 10.4 0.6 2.3 1 0 0 1 1 1 0 LisH SDA1 PF05285.12 CRJ89969.1 - 1 8.7 15.9 2.7 7.3 3.9 2.3 2 0 0 2 2 2 0 SDA1 YL1 PF05764.13 CRJ89969.1 - 5.5 7.0 22.1 11 6.0 6.9 2.6 2 0 0 2 2 2 0 YL1 nuclear protein DUF1751 PF08551.10 CRJ89985.1 - 6.4e-27 94.0 4.1 6.4e-27 94.0 4.1 1.9 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 CRJ89985.1 - 0.62 10.1 12.0 1.1 9.3 12.0 1.3 1 0 0 1 1 1 0 Rhomboid family Ribosomal_L3 PF00297.22 CRJ89992.1 - 0 1147.6 29.3 9.9e-175 580.9 10.9 2.2 2 0 0 2 2 2 2 Ribosomal protein L3 TPR_1 PF00515.28 CRJ89992.1 - 2.6e-94 305.5 59.4 2.6e-07 30.2 0.0 19.5 20 0 0 20 20 20 16 Tetratricopeptide repeat TPR_2 PF07719.17 CRJ89992.1 - 1.4e-83 268.4 52.8 2.7e-05 24.0 0.0 19.5 20 0 0 20 20 19 18 Tetratricopeptide repeat Chorismate_bind PF00425.18 CRJ89992.1 - 9.4e-76 254.8 0.2 4.3e-74 249.3 0.0 3.4 4 0 0 4 4 4 1 chorismate binding enzyme TPR_8 PF13181.6 CRJ89992.1 - 1.5e-69 224.4 39.7 8.7e-06 25.6 0.0 20.6 20 0 0 20 20 20 14 Tetratricopeptide repeat TPR_16 PF13432.6 CRJ89992.1 - 1.3e-52 176.1 36.2 1.5e-06 28.8 0.1 13.1 8 4 6 14 14 14 10 Tetratricopeptide repeat TPR_12 PF13424.6 CRJ89992.1 - 3.7e-43 145.7 45.9 2.6e-05 24.4 0.7 12.7 9 2 3 12 12 12 8 Tetratricopeptide repeat TPR_19 PF14559.6 CRJ89992.1 - 1.5e-40 137.5 46.0 0.00025 21.5 0.1 12.7 10 2 2 12 12 12 10 Tetratricopeptide repeat TPR_11 PF13414.6 CRJ89992.1 - 2.5e-40 135.9 68.2 1.5e-05 24.6 0.2 17.8 10 6 8 18 18 18 10 TPR repeat TPR_14 PF13428.6 CRJ89992.1 - 8.9e-40 132.0 42.1 0.00081 20.0 0.1 15.7 6 4 12 18 18 18 10 Tetratricopeptide repeat TPR_17 PF13431.6 CRJ89992.1 - 1.8e-37 125.0 50.4 0.0099 16.2 0.0 17.5 19 0 0 19 19 16 10 Tetratricopeptide repeat TPR_6 PF13174.6 CRJ89992.1 - 8.5e-34 114.0 38.5 0.0015 19.1 0.0 16.4 16 0 0 16 16 16 9 Tetratricopeptide repeat TPR_7 PF13176.6 CRJ89992.1 - 2.3e-27 93.0 35.9 0.042 13.9 0.1 17.6 19 0 0 19 19 18 7 Tetratricopeptide repeat ANAPC3 PF12895.7 CRJ89992.1 - 6.6e-25 87.2 33.1 2.9e-08 33.8 2.2 6.4 6 0 0 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 Anth_synt_I_N PF04715.13 CRJ89992.1 - 1.6e-23 83.5 0.1 4.3e-21 75.6 0.0 3.6 3 1 0 3 3 3 1 Anthranilate synthase component I, N terminal region TPR_9 PF13371.6 CRJ89992.1 - 6.6e-23 80.7 44.9 0.0046 17.1 0.1 12.6 6 4 8 14 14 14 11 Tetratricopeptide repeat TPR_15 PF13429.6 CRJ89992.1 - 8.5e-13 48.1 31.1 0.0056 15.9 5.8 7.5 2 2 2 6 6 6 6 Tetratricopeptide repeat TPR_21 PF09976.9 CRJ89992.1 - 4.9e-10 39.4 26.6 0.14 11.8 0.6 7.9 6 4 2 8 8 6 6 Tetratricopeptide repeat-like domain TPR_20 PF14561.6 CRJ89992.1 - 1.3e-07 31.8 12.5 1 9.7 0.4 5.9 4 2 2 6 6 6 3 Tetratricopeptide repeat DUF2225 PF09986.9 CRJ89992.1 - 0.0081 15.9 9.2 5.1 6.8 0.0 5.4 2 2 2 5 5 5 2 Uncharacterized protein conserved in bacteria (DUF2225) DUF4919 PF16266.5 CRJ89992.1 - 0.0082 16.1 0.6 8.3 6.3 0.0 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4919) DUF1639 PF07797.14 CRJ89992.1 - 0.016 15.2 0.0 4.4 7.3 0.0 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1639) BTAD PF03704.17 CRJ89992.1 - 0.092 13.2 22.9 5.9 7.3 0.6 6.0 5 1 0 6 6 6 0 Bacterial transcriptional activator domain Fis1_TPR_C PF14853.6 CRJ89992.1 - 0.1 12.7 12.2 35 4.6 0.0 7.2 10 0 0 10 10 8 0 Fis1 C-terminal tetratricopeptide repeat DUF2464 PF10240.9 CRJ89992.1 - 0.53 9.8 7.1 7.1 6.1 0.0 3.6 3 0 0 3 3 2 0 Multivesicular body subunit 12 ChAPs PF09295.10 CRJ89992.1 - 1 8.3 5.4 13 4.7 0.0 3.4 4 0 0 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) Chorismate_bind PF00425.18 CRJ90021.1 - 2.8e-90 302.4 0.0 3.6e-89 298.7 0.0 2.1 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 CRJ90021.1 - 4.1e-26 91.9 0.2 5.5e-22 78.5 0.0 4.0 3 1 0 3 3 3 2 Anthranilate synthase component I, N terminal region Helo_like_N PF17111.5 CRJ90030.1 - 0.029 13.8 0.3 0.068 12.5 0.3 1.7 1 1 0 1 1 1 0 Fungal N-terminal domain of STAND proteins RGS PF00615.19 CRJ90037.1 - 0.036 14.3 0.0 0.08 13.2 0.0 1.5 2 0 0 2 2 2 0 Regulator of G protein signaling domain Sugar_tr PF00083.24 CRJ90046.1 - 6.6e-103 345.0 20.9 7.1e-78 262.5 13.8 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CRJ90046.1 - 1.8e-21 76.4 27.7 1.8e-21 76.4 27.7 2.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Pkinase PF00069.25 CRJ90046.1 - 1.5e-08 34.4 0.0 0.00023 20.6 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CRJ90046.1 - 0.00028 20.2 0.0 0.0031 16.8 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase MFS_1 PF07690.16 CRJ90052.1 - 3.8e-37 128.0 39.3 3.8e-37 128.0 39.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CRJ90052.1 - 3.6e-10 39.3 9.1 3.6e-10 39.3 9.1 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter adh_short PF00106.25 CRJ90059.1 - 3e-34 118.2 0.0 3.9e-34 117.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRJ90059.1 - 7e-27 94.5 0.0 1.3e-26 93.6 0.0 1.4 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRJ90059.1 - 1.6e-11 44.5 1.6 8.3e-11 42.1 1.6 1.9 1 1 0 1 1 1 1 KR domain Crp PF00325.20 CRJ90059.1 - 0.024 14.3 0.2 0.045 13.4 0.2 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family PALP PF00291.25 CRJ90059.1 - 0.07 12.5 0.3 0.18 11.2 0.3 1.8 1 1 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme DUF1776 PF08643.10 CRJ90059.1 - 0.079 12.3 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DUF2235 PF09994.9 CRJ90071.1 - 6.1e-43 147.2 0.1 1e-42 146.5 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) MMR_HSR1 PF01926.23 CRJ90071.1 - 9.9e-06 25.6 0.0 2.9e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CRJ90071.1 - 2.1e-05 24.5 0.0 5.8e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 RsgA GTPase Roc PF08477.13 CRJ90071.1 - 0.00043 20.5 0.0 0.0074 16.5 0.0 2.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Septin PF00735.18 CRJ90071.1 - 0.0011 18.3 0.1 0.0097 15.2 0.0 2.2 2 0 0 2 2 2 1 Septin ABC_tran PF00005.27 CRJ90071.1 - 0.0013 19.3 0.3 0.0062 17.1 0.0 2.3 3 0 0 3 3 2 1 ABC transporter Ras PF00071.22 CRJ90071.1 - 0.0019 17.8 0.2 0.066 12.8 0.0 2.8 2 1 0 2 2 2 1 Ras family AAA_22 PF13401.6 CRJ90071.1 - 0.0065 16.7 0.0 0.032 14.5 0.0 2.2 1 0 0 1 1 1 1 AAA domain FeoB_N PF02421.18 CRJ90071.1 - 0.016 14.8 0.0 0.079 12.5 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_29 PF13555.6 CRJ90071.1 - 0.017 14.8 0.0 0.038 13.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.20 CRJ90071.1 - 0.066 12.4 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit AAA_24 PF13479.6 CRJ90071.1 - 0.088 12.5 0.0 0.28 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CRJ90071.1 - 0.093 13.1 0.0 1.3 9.4 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.6 CRJ90071.1 - 0.095 12.9 0.0 0.51 10.5 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CRJ90071.1 - 0.098 13.0 0.0 0.31 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 CRJ90071.1 - 0.12 11.5 0.0 0.24 10.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Rad17 PF03215.15 CRJ90071.1 - 0.13 12.1 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain RPN6_N PF18055.1 CRJ90093.1 - 4.3e-34 117.4 2.0 4.3e-34 117.4 2.0 2.1 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 CRJ90093.1 - 1.8e-21 76.6 0.4 1.2e-20 74.0 0.2 2.3 2 0 0 2 2 2 1 PCI domain RPN6_C_helix PF18503.1 CRJ90093.1 - 1.6e-09 37.4 0.2 4.1e-09 36.0 0.2 1.8 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain DDRGK PF09756.9 CRJ90093.1 - 4.3e-05 23.2 2.3 0.0001 21.9 0.3 2.1 2 0 0 2 2 2 1 DDRGK domain TPR_7 PF13176.6 CRJ90093.1 - 0.0063 16.5 1.3 0.27 11.3 0.2 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat DprA_WH PF17782.1 CRJ90093.1 - 0.052 13.7 0.0 0.22 11.7 0.0 2.0 2 0 0 2 2 2 0 DprA winged helix domain HTH_Crp_2 PF13545.6 CRJ90093.1 - 0.054 13.5 0.9 0.26 11.3 0.0 2.5 2 1 1 3 3 3 0 Crp-like helix-turn-helix domain RuvA_C PF07499.13 CRJ90093.1 - 0.28 11.7 1.8 2.7 8.5 0.2 3.3 3 1 1 4 4 4 0 RuvA, C-terminal domain HET PF06985.11 CRJ90106.1 - 4e-25 88.9 0.0 7.3e-25 88.0 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AIP3 PF03915.13 CRJ90114.1 - 8.7e-148 492.8 7.8 1.6e-147 491.9 7.8 1.4 1 0 0 1 1 1 1 Actin interacting protein 3 FAD_binding_3 PF01494.19 CRJ90114.1 - 3.3e-19 69.4 1.5 9.7e-18 64.5 1.5 2.6 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 CRJ90114.1 - 1.4e-05 25.2 0.0 4e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 CRJ90114.1 - 0.00066 18.5 0.0 0.0013 17.5 0.0 1.5 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 CRJ90114.1 - 0.0007 20.1 1.4 0.0023 18.4 0.0 2.7 3 0 0 3 3 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CRJ90114.1 - 0.00081 18.7 0.0 0.0016 17.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 CRJ90114.1 - 0.0016 17.6 0.0 0.0038 16.3 0.0 1.5 2 0 0 2 2 2 1 Squalene epoxidase Lycopene_cycl PF05834.12 CRJ90114.1 - 0.0018 17.4 0.1 0.01 14.9 0.0 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 CRJ90114.1 - 0.0027 17.3 0.2 0.0027 17.3 0.2 2.7 3 1 1 4 4 4 1 FAD dependent oxidoreductase ApbA PF02558.16 CRJ90114.1 - 0.012 15.3 0.0 0.034 13.8 0.0 1.8 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.6 CRJ90114.1 - 0.018 15.0 0.0 0.086 12.8 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 CRJ90114.1 - 0.019 13.8 0.0 0.032 13.1 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase NAD_Gly3P_dh_N PF01210.23 CRJ90114.1 - 0.02 14.9 0.0 1 9.4 0.0 2.5 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NPV_P10 PF05531.12 CRJ90114.1 - 0.04 14.4 7.4 0.063 13.7 0.5 3.9 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein FAD_binding_2 PF00890.24 CRJ90114.1 - 0.044 12.9 0.0 0.085 11.9 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain Wtap PF17098.5 CRJ90114.1 - 0.057 13.3 2.9 0.091 12.7 0.5 2.4 2 0 0 2 2 2 0 WTAP/Mum2p family Lectin_N PF03954.14 CRJ90114.1 - 0.095 12.5 0.1 0.095 12.5 0.1 3.3 3 1 0 3 3 3 0 Hepatic lectin, N-terminal domain Thi4 PF01946.17 CRJ90114.1 - 0.1 11.8 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Thi4 family MIP-T3_C PF17749.1 CRJ90114.1 - 5.3 7.0 9.8 0.47 10.4 0.6 3.1 3 0 0 3 3 3 0 Microtubule-binding protein MIP-T3 C-terminal region DUF4407 PF14362.6 CRJ90114.1 - 5.5 6.2 10.0 0.35 10.2 0.2 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) TraF_2 PF13729.6 CRJ90114.1 - 8.1 5.7 7.1 2.4 7.5 0.2 2.7 3 0 0 3 3 3 0 F plasmid transfer operon, TraF, protein ATP-synt_Eps PF04627.13 CRJ90123.1 - 5.7e-21 74.3 1.6 5.7e-21 74.3 1.6 1.5 2 0 0 2 2 2 1 Mitochondrial ATP synthase epsilon chain Mito_carr PF00153.27 CRJ90145.1 - 1.2e-52 175.7 3.8 1.8e-16 59.9 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Myb_DNA-binding PF00249.31 CRJ90153.1 - 4.7e-08 33.1 0.0 0.0023 18.1 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain DS PF01916.17 CRJ90164.1 - 9.2e-131 435.3 0.0 1.1e-130 435.1 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Inhibitor_I10 PF12559.8 CRJ90164.1 - 0.11 12.8 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Serine endopeptidase inhibitors Pro_isomerase PF00160.21 CRJ90171.1 - 4.5e-32 111.5 0.0 3.1e-31 108.8 0.0 2.4 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD HSF_DNA-bind PF00447.17 CRJ90178.1 - 7.8e-28 96.9 0.2 1.6e-27 96.0 0.2 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Ets PF00178.22 CRJ90178.1 - 0.18 12.3 0.0 0.43 11.1 0.0 1.6 1 0 0 1 1 1 0 Ets-domain AD PF09793.9 CRJ90178.1 - 0.59 10.3 2.7 0.47 10.6 0.2 2.0 2 0 0 2 2 2 0 Anticodon-binding domain Arrestin_C PF02752.22 CRJ90193.1 - 2.6e-07 31.1 0.1 8.2e-07 29.6 0.0 1.9 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain CAGE1 PF15066.6 CRJ90362.1 - 0.62 8.7 8.6 0.67 8.6 8.6 1.0 1 0 0 1 1 1 0 Cancer-associated gene protein 1 family DBP10CT PF08147.12 CRJ90596.1 - 1.1e-22 80.0 6.6 1.7e-22 79.4 6.6 1.3 1 0 0 1 1 1 1 DBP10CT (NUC160) domain MFS_1 PF07690.16 CRJ90596.1 - 7.2e-11 41.6 6.1 9.3e-11 41.2 6.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CRJ90596.1 - 1.7e-06 27.2 3.4 2.4e-06 26.7 3.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter AP2 PF00847.20 CRJ90596.1 - 0.039 14.2 6.5 0.14 12.4 4.7 2.6 2 1 0 2 2 2 0 AP2 domain PUF PF00806.19 CRJ90697.1 - 1.7e-29 99.8 0.1 2.3e-06 27.0 0.0 4.3 4 0 0 4 4 4 4 Pumilio-family RNA binding repeat ATP_bind_3 PF01171.20 CRJ90697.1 - 0.032 14.0 0.0 0.048 13.4 0.0 1.3 1 0 0 1 1 1 0 PP-loop family PAD_porph PF04371.15 CRJ90697.1 - 0.07 12.4 0.0 0.093 12.0 0.0 1.2 1 0 0 1 1 1 0 Porphyromonas-type peptidyl-arginine deiminase DUF2237 PF09996.9 CRJ90697.1 - 0.085 12.9 0.2 0.26 11.3 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2237) DNA_pol_phi PF04931.13 CRJ90697.1 - 0.24 9.4 0.6 0.3 9.2 0.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi bZIP_2 PF07716.15 CRJ90950.1 - 6.2e-12 45.4 10.0 9.7e-12 44.8 10.0 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 CRJ90950.1 - 0.0012 18.9 7.9 0.0022 18.1 7.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor TSC22 PF01166.18 CRJ90950.1 - 0.069 13.5 0.3 0.13 12.6 0.3 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family Ly49 PF08391.10 CRJ90950.1 - 0.59 10.5 2.3 0.77 10.1 2.3 1.2 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region APC_u14 PF16635.5 CRJ90950.1 - 2.9 8.5 9.6 0.91 10.1 4.5 2.4 2 1 0 2 2 2 0 Unstructured region on APC between SAMP and APC_crr GIT_CC PF16559.5 CRJ90950.1 - 3.1 7.7 6.0 0.25 11.3 0.9 1.8 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor CS PF04969.16 CRJ91030.1 - 1e-09 39.2 0.0 1.7e-09 38.6 0.0 1.4 1 0 0 1 1 1 1 CS domain Anillin PF08174.11 CRJ91030.1 - 0.13 12.7 0.0 0.15 12.5 0.0 1.3 1 0 0 1 1 1 0 Cell division protein anillin Glyco_hydro_3 PF00933.21 CRJ91211.1 - 7.7e-09 35.4 0.0 1.4e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain CCSMST1 PF15013.6 CRJ91211.1 - 0.15 12.3 0.0 0.26 11.5 0.0 1.3 1 0 0 1 1 1 0 CCSMST1 family DUF2686 PF10887.8 CRJ91211.1 - 0.17 10.8 0.0 0.33 9.8 0.0 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2686) ILVD_EDD PF00920.21 CRJ91250.1 - 0.003 16.2 0.0 0.0032 16.2 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family Sas10 PF09368.10 CRJ91491.1 - 2.2e-26 92.1 5.7 2.2e-26 92.1 5.7 2.2 2 0 0 2 2 2 1 Sas10 C-terminal domain adh_short PF00106.25 CRJ91491.1 - 4.7e-26 91.4 0.0 1e-25 90.4 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRJ91491.1 - 2.8e-17 63.1 0.0 6.7e-17 61.8 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Sas10_Utp3 PF04000.15 CRJ91491.1 - 2.1e-10 41.0 0.0 5.9e-10 39.6 0.0 1.8 1 0 0 1 1 1 1 Sas10/Utp3/C1D family KR PF08659.10 CRJ91491.1 - 3.8e-07 30.2 0.1 1.9e-06 27.9 0.0 2.1 2 0 0 2 2 2 1 KR domain Shikimate_DH PF01488.20 CRJ91491.1 - 0.14 12.2 0.0 0.37 10.8 0.0 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.19 CRJ91491.1 - 0.19 11.0 0.0 0.36 10.1 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DFP PF04127.15 CRJ91491.1 - 3 7.6 12.4 0.88 9.4 1.3 3.2 3 0 0 3 3 3 0 DNA / pantothenate metabolism flavoprotein Urb2 PF10441.9 CRJ91499.1 - 7e-62 209.0 0.1 2.3e-61 207.3 0.1 2.0 1 0 0 1 1 1 1 Urb2/Npa2 family DUF543 PF04418.12 CRJ91510.1 - 2.1e-29 101.3 0.0 2.4e-29 101.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) ABC_cobalt PF09819.9 CRJ91510.1 - 0.071 13.3 0.0 0.083 13.0 0.0 1.1 1 0 0 1 1 1 0 ABC-type cobalt transport system, permease component Fe-S_biosyn PF01521.20 CRJ91517.1 - 2.2e-12 47.2 0.0 1.2e-10 41.6 0.0 2.2 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis Ribosomal_L30_N PF08079.12 CRJ91526.1 - 2.1e-28 98.3 30.1 5.2e-24 84.3 18.1 2.5 2 0 0 2 2 2 2 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 CRJ91526.1 - 1.2e-15 57.2 2.4 1.2e-15 57.2 2.4 1.9 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e DUF4578 PF15147.6 CRJ91526.1 - 1.2 10.0 5.5 1 10.3 1.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4578) MAS20 PF02064.15 CRJ91526.1 - 1.3 9.2 7.9 8.7 6.5 2.7 2.4 2 0 0 2 2 2 0 MAS20 protein import receptor DUF5384 PF17358.2 CRJ91526.1 - 2.1 8.4 18.9 1.3 9.1 0.7 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5384) DUF2956 PF11169.8 CRJ91526.1 - 2.2 8.5 11.4 0.59 10.4 5.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) Ribosomal_S11 PF00411.19 CRJ91535.1 - 3.1e-46 156.3 1.2 3.9e-46 156.0 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 BKACE PF05853.12 CRJ91535.1 - 0.067 12.5 0.1 0.085 12.2 0.1 1.1 1 0 0 1 1 1 0 beta-keto acid cleavage enzyme CBM_25 PF03423.13 CRJ91535.1 - 0.084 13.1 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) SNF2_N PF00176.23 CRJ91545.1 - 1.3e-68 231.3 0.1 2.6e-68 230.3 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CRJ91545.1 - 1.9e-18 66.8 0.0 5.4e-18 65.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CRJ91545.1 - 3.9e-09 36.7 0.0 1.4e-08 34.9 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 CRJ91545.1 - 0.00045 19.5 0.0 0.0016 17.7 0.0 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 TFIIE_beta PF02186.15 CRJ91545.1 - 0.0096 16.2 0.4 0.036 14.4 0.0 2.2 2 0 0 2 2 2 1 TFIIE beta subunit core domain FliJ PF02050.16 CRJ91545.1 - 0.72 10.1 21.1 0.048 13.9 13.1 3.0 3 0 0 3 3 3 0 Flagellar FliJ protein Spc7 PF08317.11 CRJ91545.1 - 1.6 7.5 13.8 4.3 6.1 13.8 1.7 1 0 0 1 1 1 0 Spc7 kinetochore protein FapA PF03961.13 CRJ91545.1 - 1.7 7.2 8.1 3.5 6.1 8.1 1.5 1 0 0 1 1 1 0 Flagellar Assembly Protein A Hemerythrin PF01814.23 CRJ91561.1 - 5.2e-13 49.8 1.3 8.1e-13 49.1 1.3 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain eIF-3c_N PF05470.12 CRJ91569.1 - 5.2e-177 589.8 25.6 5.2e-177 589.8 25.6 3.0 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Dynactin_p22 PF07426.11 CRJ91569.1 - 0.0024 17.8 3.3 0.0082 16.0 3.3 2.0 1 0 0 1 1 1 1 Dynactin subunit p22 DASH_Ask1 PF08655.10 CRJ91569.1 - 0.11 12.4 0.2 0.29 11.0 0.2 1.7 1 0 0 1 1 1 0 DASH complex subunit Ask1 Nop14 PF04147.12 CRJ91569.1 - 0.2 9.8 27.1 0.35 9.0 27.1 1.4 1 0 0 1 1 1 0 Nop14-like family IFT57 PF10498.9 CRJ91569.1 - 1.1 8.1 26.6 0.28 10.1 22.3 2.1 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 SDA1 PF05285.12 CRJ91569.1 - 5.7 6.3 39.0 11 5.3 39.0 1.5 1 0 0 1 1 1 0 SDA1 PRO8NT PF08082.11 CRJ91578.1 - 5.2e-79 263.5 2.4 1.1e-78 262.5 2.4 1.5 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain RRM_4 PF10598.9 CRJ91578.1 - 1.4e-46 156.8 0.2 2.5e-46 156.0 0.2 1.4 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 Corona_5a PF06336.11 CRJ91578.1 - 0.39 10.7 0.0 0.39 10.7 0.0 2.4 3 0 0 3 3 3 0 Coronavirus 5a protein Hemerythrin PF01814.23 CRJ91583.1 - 5.8e-13 49.6 1.0 9.7e-13 48.9 1.0 1.4 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain eIF-3c_N PF05470.12 CRJ91590.1 - 3.2e-131 438.6 5.8 7.4e-88 295.4 4.6 2.1 2 0 0 2 2 2 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 CRJ91590.1 - 8.8e-13 48.7 0.1 2.5e-12 47.2 0.1 1.9 1 0 0 1 1 1 1 PCI domain PROCN PF08083.11 CRJ91596.1 - 3.6e-233 773.6 9.5 4.5e-233 773.3 9.5 1.1 1 0 0 1 1 1 1 PROCN (NUC071) domain PRO8NT PF08082.11 CRJ91596.1 - 2.2e-57 193.3 2.4 2.2e-57 193.3 2.4 2.0 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain eIF-3c_N PF05470.12 CRJ91603.1 - 7.1e-08 31.2 0.7 7.1e-08 31.2 0.7 2.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus CDC45 PF02724.14 CRJ91603.1 - 0.015 13.6 24.0 0.019 13.3 24.0 1.0 1 0 0 1 1 1 0 CDC45-like protein Mpp10 PF04006.12 CRJ91603.1 - 0.2 10.0 25.4 0.24 9.8 25.4 1.0 1 0 0 1 1 1 0 Mpp10 protein DUF2457 PF10446.9 CRJ91603.1 - 0.27 10.3 33.1 0.36 9.9 33.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.12 CRJ91603.1 - 0.39 8.9 28.6 0.46 8.6 28.6 1.0 1 0 0 1 1 1 0 Nop14-like family SpoIIIAH PF12685.7 CRJ91603.1 - 1.1 9.1 16.6 1.3 8.8 16.6 1.0 1 0 0 1 1 1 0 SpoIIIAH-like protein DNA_pol_phi PF04931.13 CRJ91603.1 - 6.4 4.7 35.7 7.4 4.5 35.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 CRJ91603.1 - 8.4 5.7 34.8 10 5.4 34.8 1.1 1 0 0 1 1 1 0 SDA1 PROCN PF08083.11 CRJ91608.1 - 5.7e-232 769.6 9.5 5.7e-232 769.6 9.5 1.8 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 CRJ91608.1 - 2.1e-153 508.5 6.2 2.8e-127 423.0 1.1 2.5 2 0 0 2 2 2 2 PRP8 domain IV core U6-snRNA_bdg PF10596.9 CRJ91608.1 - 6e-84 279.8 2.9 1.9e-57 193.6 0.2 3.1 3 0 0 3 3 3 2 U6-snRNA interacting domain of PrP8 PROCT PF08084.11 CRJ91608.1 - 3.2e-72 240.2 4.9 1.4e-43 147.7 0.0 3.4 4 0 0 4 4 4 2 PROCT (NUC072) domain U5_2-snRNA_bdg PF10597.9 CRJ91608.1 - 1.6e-71 238.6 0.1 3.3e-71 237.6 0.1 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 CRJ91608.1 - 7.1e-46 154.5 0.2 1.8e-45 153.2 0.2 1.7 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 Hom_end_hint PF05203.16 CRJ91608.1 - 2.1e-08 34.4 1.5 3.6e-08 33.6 0.0 2.1 2 0 0 2 2 2 1 Hom_end-associated Hint Myb_DNA-bind_6 PF13921.6 CRJ91608.1 - 9.8e-08 32.1 0.1 3e-07 30.6 0.1 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 CRJ91608.1 - 0.00084 19.5 0.0 0.0023 18.1 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Hom_end PF05204.14 CRJ91608.1 - 0.0018 18.4 0.0 0.017 15.3 0.0 2.7 3 0 0 3 3 3 1 Homing endonuclease DUF4393 PF14337.6 CRJ91608.1 - 0.0059 16.4 0.0 6 6.6 0.0 2.9 2 0 0 2 2 2 2 Domain of unknown function (DUF4393) Rapsyn_N PF10579.9 CRJ91608.1 - 0.073 13.2 0.8 20 5.4 0.1 2.8 2 0 0 2 2 2 0 Rapsyn N-terminal myristoylation and linker region Myb_DNA-bind_6 PF13921.6 CRJ91614.1 - 4.1e-14 52.6 0.4 1.3e-07 31.7 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 CRJ91614.1 - 4.4e-13 49.2 0.1 1.1e-05 25.5 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain HTH_AsnC-type PF13404.6 CRJ91614.1 - 0.017 14.9 0.0 1 9.2 0.0 2.4 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain AtuA PF07287.11 CRJ91614.1 - 0.19 10.4 0.0 0.29 9.8 0.0 1.1 1 0 0 1 1 1 0 Acyclic terpene utilisation family protein AtuA ApbA_C PF08546.11 CRJ91620.1 - 1.3e-29 103.0 0.0 2.2e-29 102.2 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 CRJ91620.1 - 7.9e-20 71.0 0.0 1.6e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA MOZART1 PF12554.8 CRJ91620.1 - 0.006 16.3 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated Pyr_redox_2 PF07992.14 CRJ91620.1 - 0.15 11.3 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_hydro_85 PF03644.13 CRJ91620.1 - 0.19 11.1 0.0 0.51 9.7 0.0 1.7 2 0 0 2 2 2 0 Glycosyl hydrolase family 85 TPR_12 PF13424.6 CRJ91625.1 - 3.1e-12 46.6 15.9 3.5e-07 30.4 0.0 6.1 4 2 3 7 7 7 3 Tetratricopeptide repeat TPR_10 PF13374.6 CRJ91625.1 - 1.1e-06 28.3 11.2 0.13 12.2 0.2 5.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 CRJ91625.1 - 6.8e-06 26.5 14.4 1 10.4 0.3 6.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 CRJ91625.1 - 2.8e-05 23.9 14.7 0.67 10.2 0.1 7.3 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_1 PF00515.28 CRJ91625.1 - 0.00099 18.8 6.8 3.1 7.8 0.2 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 CRJ91625.1 - 0.0037 17.9 10.2 5.4 7.7 0.2 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 CRJ91625.1 - 0.0048 17.0 8.2 0.75 10.2 0.2 5.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 CRJ91625.1 - 0.082 13.0 13.8 7.5 6.8 0.0 5.7 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_19 PF14559.6 CRJ91625.1 - 3.3 8.3 10.0 22 5.6 0.1 5.0 5 1 0 5 5 5 0 Tetratricopeptide repeat DUF4449 PF14613.6 CRJ91630.1 - 0.0032 17.6 0.1 0.014 15.5 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) YgaB PF14182.6 CRJ91639.1 - 2.1 8.8 10.5 1.2 9.6 1.5 2.9 3 0 0 3 3 3 0 YgaB-like protein AAA PF00004.29 CRJ91651.1 - 7.4e-16 58.8 0.0 1.8e-15 57.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CRJ91651.1 - 0.0023 18.4 0.3 0.01 16.2 0.3 2.3 1 1 0 1 1 1 1 AAA ATPase domain ATPase PF06745.13 CRJ91651.1 - 0.0095 15.3 0.1 0.019 14.3 0.1 1.5 1 0 0 1 1 1 1 KaiC AAA_5 PF07728.14 CRJ91651.1 - 0.013 15.5 0.0 0.034 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 CRJ91651.1 - 0.021 14.5 0.0 0.049 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 CRJ91651.1 - 0.024 14.3 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_22 PF13401.6 CRJ91651.1 - 0.052 13.8 3.6 0.29 11.4 0.2 3.0 3 1 1 4 4 4 0 AAA domain AAA_3 PF07726.11 CRJ91651.1 - 0.14 12.1 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Peptidase_M28 PF04389.17 CRJ91662.1 - 5.8e-27 94.7 0.4 2.3e-26 92.7 0.4 1.8 1 1 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 CRJ91662.1 - 8.3e-07 28.9 0.0 1.2e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 CRJ91662.1 - 7.4e-05 21.9 0.1 0.00012 21.2 0.1 1.3 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase DUF4910 PF16254.5 CRJ91662.1 - 0.17 10.7 0.0 0.27 10.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4910) MAP65_ASE1 PF03999.12 CRJ91672.1 - 9.8e-77 259.0 12.1 9.8e-77 259.0 12.1 2.1 1 1 1 2 2 2 1 Microtubule associated protein (MAP65/ASE1 family) SKA2 PF16740.5 CRJ91672.1 - 0.59 9.9 7.5 0.73 9.6 1.2 3.7 4 1 1 5 5 5 0 Spindle and kinetochore-associated protein 2 Rx_N PF18052.1 CRJ91672.1 - 4.5 7.6 10.7 0.75 10.1 1.4 3.5 3 0 0 3 3 3 0 Rx N-terminal domain Spectrin PF00435.21 CRJ91672.1 - 6.5 7.3 16.7 0.61 10.6 2.2 4.7 3 2 1 4 4 4 0 Spectrin repeat OmpH PF03938.14 CRJ91672.1 - 8.9 6.7 9.5 10 6.4 0.5 3.4 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) Dynamin_N PF00350.23 CRJ91682.1 - 7e-32 110.8 0.0 1.3e-31 109.9 0.0 1.4 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 CRJ91682.1 - 0.00017 21.6 0.4 0.0021 18.1 0.4 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 CRJ91682.1 - 0.0085 16.5 0.0 0.013 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain FeoB_N PF02421.18 CRJ91682.1 - 0.018 14.5 0.1 5.5 6.5 0.1 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B AIG1 PF04548.16 CRJ91682.1 - 0.019 14.3 0.7 1.7 8.0 0.4 2.1 2 0 0 2 2 2 0 AIG1 family AAA_21 PF13304.6 CRJ91682.1 - 0.045 13.6 0.0 0.067 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 CRJ91682.1 - 0.049 13.3 0.0 0.068 12.9 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 CRJ91682.1 - 0.056 13.2 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Cation_efflux PF01545.21 CRJ91696.1 - 2.4e-45 154.7 3.1 4.3e-45 153.9 3.1 1.4 1 0 0 1 1 1 1 Cation efflux family Mito_carr PF00153.27 CRJ91696.1 - 4.7e-41 138.6 1.1 1.4e-17 63.4 0.0 3.6 3 0 0 3 3 3 3 Mitochondrial carrier protein Zip PF02535.22 CRJ91696.1 - 0.00041 19.7 6.7 0.00041 19.7 6.7 3.6 1 1 1 2 2 2 1 ZIP Zinc transporter TFIIIC_delta PF12657.7 CRJ91705.1 - 6.9e-15 55.4 0.0 2e-14 54.0 0.0 1.8 1 0 0 1 1 1 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.7 CRJ91705.1 - 4.4e-11 42.6 1.3 8.7e-11 41.7 1.3 1.5 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex DNA_topoisoIV PF00521.20 CRJ91716.1 - 3.3e-104 349.1 1.5 3.6e-101 339.1 0.3 3.0 2 1 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 CRJ91716.1 - 1.7e-48 164.1 4.2 1.7e-48 164.1 4.2 2.5 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 CRJ91716.1 - 2.7e-27 95.3 1.8 5.5e-27 94.3 1.8 1.5 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 CRJ91716.1 - 9.1e-15 55.1 0.1 2.5e-14 53.7 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 CRJ91716.1 - 1.9e-06 28.0 0.0 7.4e-06 26.1 0.0 2.1 1 0 0 1 1 1 1 Toprim domain APAF1_C PF17908.1 CRJ91716.1 - 0.015 15.3 0.4 0.053 13.5 0.4 2.0 1 0 0 1 1 1 0 APAF-1 helical domain Reticulon PF02453.17 CRJ91723.1 - 2.6e-35 121.7 3.0 3.6e-35 121.3 3.0 1.2 1 0 0 1 1 1 1 Reticulon DUF4107 PF13389.6 CRJ91723.1 - 0.014 15.6 0.0 0.023 14.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4107) FUSC_2 PF13515.6 CRJ91723.1 - 0.16 12.1 4.1 3.6 7.7 0.5 2.2 2 0 0 2 2 2 0 Fusaric acid resistance protein-like RabGAP-TBC PF00566.18 CRJ91731.1 - 1.5e-48 165.3 0.0 3e-48 164.3 0.0 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Lipase_GDSL_2 PF13472.6 CRJ91731.1 - 3.9e-06 27.4 0.1 1.7e-05 25.3 0.1 2.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 CRJ91731.1 - 4.5e-06 26.8 0.4 1.8e-05 24.8 0.0 2.2 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase DUF1687 PF07955.11 CRJ91731.1 - 2.9 8.4 7.8 0.56 10.7 3.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1687) DUF724 PF05266.14 CRJ91731.1 - 4.4 7.1 17.4 1.3 8.8 4.9 2.8 1 1 0 2 2 2 0 Protein of unknown function (DUF724) Glyco_hydro_76 PF03663.14 CRJ91741.1 - 5.7e-133 444.0 1.0 7.2e-133 443.6 1.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 CRJ91741.1 - 0.0038 16.4 6.9 0.11 11.6 0.1 3.1 2 1 1 3 3 3 2 Glycosyl Hydrolase Family 88 DUF1735 PF08522.10 CRJ91755.1 - 0.0079 16.8 0.7 0.013 16.1 0.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1735) DUF371 PF04027.13 CRJ91755.1 - 0.053 13.5 0.1 0.1 12.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF371) AF-4 PF05110.13 CRJ91755.1 - 3.3 5.7 7.9 3.6 5.5 7.9 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein MscL PF01741.18 CRJ91761.1 - 1.5e-19 70.4 0.0 1.8e-19 70.2 0.0 1.1 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL DZR PF12773.7 CRJ91761.1 - 0.022 14.8 0.7 0.033 14.2 0.7 1.2 1 0 0 1 1 1 0 Double zinc ribbon C1_1 PF00130.22 CRJ91761.1 - 0.04 13.8 1.1 0.066 13.1 1.1 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SUR7 PF06687.12 CRJ91772.1 - 1.4e-22 80.3 0.1 1.8e-22 80.0 0.1 1.0 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.8 CRJ91772.1 - 2.4 8.0 11.0 0.24 11.3 6.0 1.9 2 1 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 NDT80_PhoG PF05224.12 CRJ91789.1 - 2.5e-46 158.2 0.0 3.3e-46 157.9 0.0 1.1 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Pterin_bind PF00809.22 CRJ91794.1 - 3.2e-56 190.7 0.0 4.5e-56 190.3 0.0 1.1 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 CRJ91794.1 - 1.3e-33 115.8 0.0 2.4e-33 115.0 0.0 1.4 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) DUF3939 PF13075.6 CRJ91794.1 - 0.16 12.0 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3939) NMO PF03060.15 CRJ91803.1 - 8.3e-58 196.3 2.9 1.2e-57 195.8 2.9 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 CRJ91803.1 - 1.4e-11 44.0 3.1 2.7e-11 43.1 3.1 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 CRJ91803.1 - 1.1e-06 27.9 4.4 1.7e-06 27.3 4.4 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 CRJ91803.1 - 0.0086 15.3 1.1 0.012 14.8 0.5 1.5 2 0 0 2 2 2 1 Conserved region in glutamate synthase DHO_dh PF01180.21 CRJ91803.1 - 0.086 12.0 0.4 0.13 11.5 0.4 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase ArfGap PF01412.18 CRJ91810.1 - 1.6e-35 121.7 1.1 2.8e-35 120.9 1.1 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf KAR9 PF08580.10 CRJ91810.1 - 1 7.9 7.5 1.2 7.5 7.5 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 TIM21 PF08294.11 CRJ91820.1 - 6.9e-43 146.0 0.0 8.5e-43 145.7 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.10 CRJ91820.1 - 1.8e-07 30.9 0.0 3.3e-07 30.1 0.0 1.4 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 LrgB PF04172.16 CRJ91833.1 - 0.0003 20.4 2.2 0.45 10.0 0.0 2.3 2 0 0 2 2 2 2 LrgB-like family zf-H2C2_2 PF13465.6 CRJ91847.1 - 5.4e-09 36.1 21.3 1.9e-05 24.9 3.5 4.5 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 CRJ91847.1 - 1.2e-06 28.6 20.0 0.00043 20.6 4.5 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 CRJ91847.1 - 0.02 15.2 3.0 0.05 13.9 0.4 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CRJ91847.1 - 0.027 14.5 2.3 2.2 8.3 0.3 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_4 PF13894.6 CRJ91847.1 - 0.049 14.5 3.1 0.049 14.5 3.1 3.7 4 0 0 4 4 4 0 C2H2-type zinc finger FOXP-CC PF16159.5 CRJ91847.1 - 0.12 13.0 0.2 0.12 13.0 0.2 2.8 2 1 1 3 3 3 0 FOXP coiled-coil domain DUF2225 PF09986.9 CRJ91847.1 - 0.35 10.6 0.8 0.93 9.2 0.8 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-H2C2_5 PF13909.6 CRJ91847.1 - 1 9.2 11.9 2.9 7.7 0.1 3.8 3 0 0 3 3 3 0 C2H2-type zinc-finger domain PHD PF00628.29 CRJ92145.1 - 6.7e-10 38.7 1.8 6.7e-10 38.7 1.8 1.6 2 0 0 2 2 2 1 PHD-finger UIM PF02809.20 CRJ92145.1 - 0.0002 21.1 3.6 0.00057 19.6 3.6 1.8 1 0 0 1 1 1 1 Ubiquitin interaction motif PHD_2 PF13831.6 CRJ92145.1 - 0.00041 19.8 2.6 0.00068 19.1 2.6 1.4 1 0 0 1 1 1 1 PHD-finger CEBP_ZZ PF16366.5 CRJ92145.1 - 0.012 15.8 1.6 0.021 15.0 1.6 1.3 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain zf-CW PF07496.15 CRJ92145.1 - 0.29 11.2 4.7 0.87 9.7 4.8 1.7 1 1 0 1 1 1 0 CW-type Zinc Finger Glyco_transf_20 PF00982.21 CRJ92423.1 - 1.9e-51 175.3 0.0 2.1e-51 175.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Sugar_tr PF00083.24 CRJ92572.1 - 1.5e-28 99.8 8.0 1.8e-28 99.6 8.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter HigB_toxin PF09907.9 CRJ92572.1 - 0.072 13.3 0.1 0.19 11.9 0.1 1.7 2 0 0 2 2 2 0 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system CHD5 PF04420.14 CRJ92572.1 - 0.26 11.1 1.0 4.5 7.1 0.3 2.4 1 1 1 2 2 2 0 CHD5-like protein EF-hand_1 PF00036.32 CRJ92834.1 - 7.7e-14 50.1 4.4 1.4e-10 40.0 2.3 2.1 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 CRJ92834.1 - 2.1e-12 46.7 0.4 4.7e-11 42.4 0.3 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.6 CRJ92834.1 - 3e-10 40.4 0.1 7.6e-09 35.9 0.2 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 CRJ92834.1 - 1e-09 37.4 3.9 9.6e-07 28.0 1.8 2.2 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 CRJ92834.1 - 2.9e-09 36.1 0.3 9.9e-06 25.1 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_9 PF14658.6 CRJ92834.1 - 0.012 16.0 0.2 0.039 14.3 0.0 1.8 2 0 0 2 2 2 0 EF-hand domain EF-hand_4 PF12763.7 CRJ92834.1 - 0.045 13.7 0.0 0.047 13.6 0.0 1.2 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand Pkinase PF00069.25 CRJ93126.1 - 1.2e-05 24.9 0.0 1.7e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain CN_hydrolase PF00795.22 CRJ93250.1 - 3.9e-24 85.4 0.0 8.6e-24 84.3 0.0 1.5 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase adh_short PF00106.25 CRJ93441.1 - 1.7e-50 171.2 0.3 2.3e-50 170.8 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRJ93441.1 - 1.3e-33 116.5 0.9 1.9e-33 116.0 0.9 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRJ93441.1 - 2.7e-12 47.0 0.1 4.9e-12 46.1 0.1 1.4 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 CRJ93441.1 - 0.043 13.6 0.1 0.099 12.4 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase FolB PF02152.18 CRJ93441.1 - 0.086 13.4 0.0 0.19 12.3 0.0 1.5 1 0 0 1 1 1 0 Dihydroneopterin aldolase DUF1776 PF08643.10 CRJ93441.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) ThiF PF00899.21 CRJ93455.1 - 3.9e-20 72.3 0.0 6.5e-20 71.5 0.0 1.3 1 1 0 1 1 1 1 ThiF family Fungal_trans PF04082.18 CRJ93467.1 - 8.2e-22 77.5 0.1 1.5e-21 76.6 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRJ93467.1 - 3.5e-07 30.2 12.6 6.5e-07 29.4 12.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Haem_oxygenas_2 PF14518.6 CRJ93467.1 - 0.0033 17.2 0.2 0.0069 16.2 0.2 1.5 1 0 0 1 1 1 1 Iron-containing redox enzyme BatA PF07584.11 CRJ93467.1 - 0.18 12.2 3.1 16 5.9 0.3 3.8 4 0 0 4 4 4 0 Aerotolerance regulator N-terminal MoCF_biosynth PF00994.24 CRJ93486.1 - 4.4e-53 178.8 1.8 2.3e-27 95.4 0.0 2.8 3 0 0 3 3 3 2 Probable molybdopterin binding domain MoeA_N PF03453.17 CRJ93486.1 - 5.3e-39 133.5 1.9 1.1e-38 132.5 1.9 1.6 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 CRJ93486.1 - 7.4e-17 61.3 0.0 2.5e-16 59.6 0.0 2.0 2 0 0 2 2 2 1 MoeA C-terminal region (domain IV) zf-RING_5 PF14634.6 CRJ93486.1 - 1.7e-07 31.1 6.3 2.8e-07 30.4 6.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CRJ93486.1 - 0.00083 19.3 0.9 0.0018 18.3 0.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 CRJ93486.1 - 0.0019 18.0 2.4 0.0041 16.9 2.4 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 CRJ93486.1 - 0.0039 17.5 5.6 0.0071 16.7 5.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CRJ93486.1 - 0.0062 16.4 5.2 0.011 15.6 5.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CRJ93486.1 - 0.009 15.8 4.8 0.017 14.9 4.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CRJ93486.1 - 0.023 14.5 5.5 0.04 13.8 5.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Mito_carr PF00153.27 CRJ93486.1 - 0.05 13.5 0.0 0.58 10.1 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial carrier protein zf-C3HC4_4 PF15227.6 CRJ93486.1 - 1 9.6 2.7 2.3 8.5 2.7 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-MIZ PF02891.20 CRJ93486.1 - 2.9 7.7 4.3 5.5 6.8 4.3 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger ATP-synt_C PF00137.21 CRJ93503.1 - 5.6e-19 68.3 25.5 1.3e-14 54.3 8.6 3.1 2 2 1 3 3 3 2 ATP synthase subunit C SLATT_5 PF18160.1 CRJ93503.1 - 0.00061 19.2 1.5 0.0011 18.3 1.5 1.3 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain family 5 DUF981 PF06168.11 CRJ93503.1 - 0.051 13.5 17.0 0.088 12.7 3.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF981) TFIIA_gamma_C PF02751.14 CRJ93514.1 - 8.2e-24 83.5 0.5 1.4e-23 82.8 0.5 1.4 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.16 CRJ93514.1 - 3e-22 78.3 0.5 4.1e-22 77.9 0.5 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain AARP2CN PF08142.12 CRJ93522.1 - 2.7e-27 94.7 0.0 9e-27 93.0 0.0 2.0 1 0 0 1 1 1 1 AARP2CN (NUC121) domain RIBIOP_C PF04950.12 CRJ93522.1 - 1.5e-24 87.0 0.2 6.8e-13 48.7 0.0 3.2 2 1 1 3 3 2 2 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AAA_22 PF13401.6 CRJ93522.1 - 1e-05 25.9 0.0 2.8e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CRJ93522.1 - 5.6e-05 23.6 0.0 0.00022 21.7 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 CRJ93522.1 - 0.00017 22.1 3.3 0.034 14.7 0.0 3.6 3 0 0 3 3 2 1 AAA domain AAA PF00004.29 CRJ93522.1 - 0.00024 21.5 0.0 0.00061 20.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 CRJ93522.1 - 0.00051 20.6 0.9 0.0046 17.5 0.0 2.6 2 0 0 2 2 2 1 ABC transporter MMR_HSR1 PF01926.23 CRJ93522.1 - 0.00054 20.0 0.0 0.002 18.2 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CRJ93522.1 - 0.0013 18.4 1.0 0.77 9.3 0.0 3.0 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain RNA_helicase PF00910.22 CRJ93522.1 - 0.0015 18.9 0.0 0.0036 17.7 0.0 1.7 1 0 0 1 1 1 1 RNA helicase NB-ARC PF00931.22 CRJ93522.1 - 0.0015 17.8 0.1 0.0048 16.1 0.0 1.8 2 0 0 2 2 2 1 NB-ARC domain AAA_33 PF13671.6 CRJ93522.1 - 0.0021 18.2 0.9 0.0072 16.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 CRJ93522.1 - 0.0022 17.9 0.0 0.005 16.8 0.0 1.7 1 1 0 1 1 1 1 NACHT domain Rad17 PF03215.15 CRJ93522.1 - 0.0034 17.3 0.2 0.13 12.2 0.0 2.9 3 0 0 3 3 3 1 Rad17 P-loop domain Ploopntkinase3 PF18751.1 CRJ93522.1 - 0.004 17.1 0.0 0.0087 16.0 0.0 1.5 1 0 0 1 1 1 1 P-loop Nucleotide Kinase3 AAA_14 PF13173.6 CRJ93522.1 - 0.0045 17.0 0.0 0.013 15.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CRJ93522.1 - 0.0092 16.3 0.0 0.025 14.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CRJ93522.1 - 0.01 15.6 0.0 0.01 15.6 0.0 1.8 2 0 0 2 2 1 0 AAA domain PduV-EutP PF10662.9 CRJ93522.1 - 0.015 15.1 0.0 0.054 13.2 0.0 1.8 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 CRJ93522.1 - 0.018 14.6 0.0 0.043 13.4 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 CRJ93522.1 - 0.025 14.1 0.1 0.1 12.1 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region ATPase_2 PF01637.18 CRJ93522.1 - 0.028 14.3 0.0 0.028 14.3 0.0 2.1 2 0 0 2 2 1 0 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 CRJ93522.1 - 0.04 13.8 0.6 0.12 12.3 0.0 2.1 3 0 0 3 3 1 0 RsgA GTPase NTPase_1 PF03266.15 CRJ93522.1 - 0.041 13.8 0.1 0.088 12.7 0.1 1.5 1 0 0 1 1 1 0 NTPase Roc PF08477.13 CRJ93522.1 - 0.042 14.1 0.0 0.13 12.5 0.0 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_5 PF07728.14 CRJ93522.1 - 0.12 12.4 2.3 0.15 12.0 0.0 2.4 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.17 CRJ93522.1 - 0.15 11.8 0.3 0.59 9.9 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_17 PF13207.6 CRJ93522.1 - 0.35 11.3 0.0 0.35 11.3 0.0 4.0 4 0 0 4 4 3 0 AAA domain BCDHK_Adom3 PF10436.9 CRJ93535.1 - 2.5e-43 147.7 0.0 4.8e-43 146.8 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 CRJ93535.1 - 3.1e-09 37.3 0.0 2e-08 34.7 0.0 2.3 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Inhibitor_I9 PF05922.16 CRJ93535.1 - 6.3e-09 36.4 0.4 1.5e-08 35.2 0.4 1.7 1 0 0 1 1 1 1 Peptidase inhibitor I9 Yip1 PF04893.17 CRJ93546.1 - 1.6e-10 41.0 17.0 2.7e-10 40.2 17.0 1.4 1 0 0 1 1 1 1 Yip1 domain DUF1282 PF06930.12 CRJ93546.1 - 0.01 15.6 5.9 0.018 14.9 5.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) Ran_BP1 PF00638.18 CRJ93556.1 - 2e-09 37.8 0.1 0.0019 18.4 0.0 2.6 2 0 0 2 2 2 2 RanBP1 domain Glyco_hydro_75 PF07335.11 CRJ93556.1 - 0.0015 18.8 0.0 0.0027 18.0 0.0 1.4 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 SDA1 PF05285.12 CRJ93556.1 - 2.4 7.5 29.2 0.053 13.0 4.0 2.2 2 0 0 2 2 2 0 SDA1 GREB1 PF15782.5 CRJ93556.1 - 7.8 3.5 9.5 12 2.8 9.5 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DEAD PF00270.29 CRJ93562.1 - 3.4e-26 92.1 0.0 6.6e-26 91.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.10 CRJ93562.1 - 1.9e-21 76.6 0.3 4.8e-21 75.3 0.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.31 CRJ93562.1 - 2e-12 47.5 0.0 6.4e-12 45.8 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CRJ93562.1 - 1.6e-07 31.4 0.0 3e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CDT1 PF08839.11 CRJ93562.1 - 3.1e-07 30.8 0.0 6.3e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 DNA replication factor CDT1 like DnaB_C PF03796.15 CRJ93562.1 - 0.11 11.8 0.1 0.31 10.3 0.0 1.8 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Mo-co_dimer PF03404.16 CRJ93571.1 - 3.9e-61 205.1 0.1 8.9e-61 203.9 0.1 1.6 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.19 CRJ93571.1 - 2.2e-56 190.2 0.0 3.7e-56 189.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.24 CRJ93571.1 - 1.8e-33 114.8 0.0 3.1e-33 114.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 CRJ93571.1 - 1.3e-27 96.6 0.0 3e-27 95.4 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 CRJ93571.1 - 2.9e-20 72.2 0.0 5.8e-20 71.2 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 CRJ93571.1 - 0.0025 18.0 0.0 0.02 15.0 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain HSP70 PF00012.20 CRJ93594.1 - 3.8e-165 550.5 5.0 3.8e-165 550.5 5.0 2.1 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 CRJ93594.1 - 1.2e-14 53.9 0.0 1.2e-13 50.6 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 CRJ93594.1 - 8.7e-05 22.9 0.7 0.19 12.1 0.1 4.0 3 1 0 3 3 3 2 Cell division protein FtsA Trans_reg_C PF00486.28 CRJ93594.1 - 0.11 12.6 0.0 0.4 10.8 0.0 2.0 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal Apolipoprotein PF01442.18 CRJ93594.1 - 2.1 8.2 19.4 1.7 8.4 16.4 2.2 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain TPR_2 PF07719.17 CRJ93611.1 - 1.7e-11 43.3 8.6 0.00014 21.7 0.1 5.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 CRJ93611.1 - 2.6e-10 39.7 2.0 0.0072 16.1 0.0 5.0 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 CRJ93611.1 - 0.00033 20.5 11.3 1.1 9.4 0.7 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 CRJ93611.1 - 0.00071 19.6 0.0 2 8.8 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.14 CRJ93611.1 - 0.01 16.4 22.6 0.023 15.3 1.2 7.0 7 1 1 8 8 8 0 Tetratricopeptide repeat TPR_11 PF13414.6 CRJ93611.1 - 0.022 14.4 1.9 3.9 7.3 0.1 4.3 4 0 0 4 4 4 0 TPR repeat TPR_16 PF13432.6 CRJ93611.1 - 0.038 14.6 1.7 0.038 14.6 1.7 6.7 7 1 0 7 7 6 0 Tetratricopeptide repeat TPR_17 PF13431.6 CRJ93611.1 - 0.055 13.9 0.8 17 6.1 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 CRJ93611.1 - 0.1 12.9 16.1 0.067 13.5 1.2 5.5 6 1 0 6 6 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 CRJ93611.1 - 0.4 11.6 29.8 1.1 10.3 1.1 7.2 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_19 PF14559.6 CRJ93611.1 - 0.44 11.1 9.0 0.43 11.1 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 CRJ93611.1 - 0.9 9.5 14.8 1.2 9.1 0.2 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat GTP_EFTU PF00009.27 CRJ93618.1 - 6.7e-35 120.4 0.0 6.7e-35 120.4 0.0 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 CRJ93618.1 - 1.4e-18 66.9 0.0 3.6e-18 65.6 0.0 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 CRJ93618.1 - 4.9e-10 39.7 6.7 9.6e-09 35.5 0.3 3.5 3 0 0 3 3 3 2 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 CRJ93618.1 - 1.6e-07 31.2 2.5 2.7e-07 30.4 0.3 2.6 2 0 0 2 2 2 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.23 CRJ93618.1 - 4.2e-07 30.1 0.2 1e-05 25.6 0.0 3.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 CRJ93618.1 - 0.00078 19.7 0.0 0.002 18.3 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 CRJ93618.1 - 0.0099 15.7 6.3 0.026 14.3 0.0 3.4 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein LtuB PF17455.2 CRJ93618.1 - 0.043 14.4 0.8 0.043 14.4 0.8 3.4 5 0 0 5 5 5 0 Late transcription unit B PLL PF18587.1 CRJ93618.1 - 0.087 13.0 0.1 56 3.9 0.0 3.4 3 0 0 3 3 3 0 PTX/LNS-Like (PLL) domain MMS1_N PF10433.9 CRJ93631.1 - 5.7e-62 209.9 0.0 5.3e-61 206.8 0.0 2.4 3 0 0 3 3 3 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Eaf7 PF07904.13 CRJ93641.1 - 1.5e-17 63.9 0.5 1.5e-17 63.9 0.5 2.5 2 1 0 2 2 1 1 Chromatin modification-related protein EAF7 CDC27 PF09507.10 CRJ93641.1 - 0.014 14.8 24.7 0.02 14.3 24.7 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Pox_Ag35 PF03286.14 CRJ93641.1 - 0.23 11.2 30.8 0.19 11.5 28.1 1.9 1 1 1 2 2 2 0 Pox virus Ag35 surface protein Mitofilin PF09731.9 CRJ93641.1 - 0.28 10.0 19.3 0.33 9.7 19.3 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein CNDH2_C PF16858.5 CRJ93641.1 - 0.29 11.0 11.5 0.57 10.0 11.5 1.5 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term NOA36 PF06524.12 CRJ93641.1 - 0.37 10.1 15.8 0.67 9.2 15.8 1.4 1 0 0 1 1 1 0 NOA36 protein PPP4R2 PF09184.11 CRJ93641.1 - 0.39 10.2 21.0 0.52 9.9 21.0 1.2 1 0 0 1 1 1 0 PPP4R2 Nucleo_P87 PF07267.11 CRJ93641.1 - 0.61 8.9 11.5 0.69 8.7 11.5 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 TFIIF_alpha PF05793.12 CRJ93641.1 - 0.72 8.4 23.2 1.1 7.8 23.2 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.12 CRJ93641.1 - 0.84 7.8 24.1 1.2 7.3 24.1 1.2 1 0 0 1 1 1 0 Nop14-like family ORC6 PF05460.13 CRJ93641.1 - 1 8.6 17.1 1.5 8.0 17.1 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) LAP1C PF05609.12 CRJ93641.1 - 3 6.8 14.0 4.1 6.4 14.0 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Sporozoite_P67 PF05642.11 CRJ93641.1 - 6.7 4.7 16.0 9.6 4.1 16.0 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Paf1 PF03985.13 CRJ93641.1 - 9.1 5.2 21.8 16 4.3 21.8 1.5 1 0 0 1 1 1 0 Paf1 DUF3073 PF11273.8 CRJ93650.1 - 0.079 13.7 1.2 0.31 11.8 0.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3073) DASH_Ask1 PF08655.10 CRJ93661.1 - 1.1e-30 105.3 0.2 1.8e-30 104.6 0.2 1.3 1 0 0 1 1 1 1 DASH complex subunit Ask1 DUF3073 PF11273.8 CRJ93661.1 - 0.54 11.0 3.6 0.44 11.3 0.5 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3073) p450 PF00067.22 CRJ93671.1 - 5.2e-89 299.1 0.0 3e-47 161.4 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 VWA_N PF08399.11 CRJ93671.1 - 0.013 16.0 2.4 0.6 10.6 0.1 2.4 2 0 0 2 2 2 0 VWA N-terminal Phage_T7_Capsid PF05396.11 CRJ93671.1 - 0.014 15.7 0.1 17 5.8 0.0 3.3 4 0 0 4 4 4 0 Phage T7 capsid assembly protein DUF503 PF04456.12 CRJ93671.1 - 0.048 13.5 0.0 16 5.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF503) DUF1729 PF08354.10 CRJ93671.1 - 0.059 12.3 0.0 12 4.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1729) DUF4507 PF14964.6 CRJ93671.1 - 0.078 11.9 0.0 11 4.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4507) Ntox30 PF15532.6 CRJ93671.1 - 0.2 12.1 0.0 36 4.8 0.0 2.4 2 0 0 2 2 2 0 Bacterial toxin 30 ROF PF07073.12 CRJ93671.1 - 0.2 11.9 0.4 35 4.6 0.0 2.5 2 0 0 2 2 2 0 Modulator of Rho-dependent transcription termination (ROF) Rhodanese PF00581.20 CRJ93688.1 - 1.6e-14 54.3 0.0 2.3e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain Yip1 PF04893.17 CRJ93696.1 - 1.9e-08 34.2 2.5 2.5e-08 33.8 2.5 1.1 1 0 0 1 1 1 1 Yip1 domain Rhodanese PF00581.20 CRJ93704.1 - 1.9e-14 54.1 0.0 2.2e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Yip1 PF04893.17 CRJ93714.1 - 4e-13 49.4 14.6 7.5e-13 48.6 14.6 1.5 1 0 0 1 1 1 1 Yip1 domain zf-RRN7 PF11781.8 CRJ93714.1 - 7.1e-10 38.4 5.2 7.1e-10 38.4 5.2 1.7 2 0 0 2 2 2 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Vps52 PF04129.12 CRJ93731.1 - 1.1e-125 420.3 0.1 1.3e-125 420.0 0.1 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.9 CRJ93731.1 - 6.7e-07 28.1 0.9 7.1e-06 24.7 0.1 2.0 2 0 0 2 2 2 1 Exocyst complex component Sec3 CENP-F_leu_zip PF10473.9 CRJ93731.1 - 0.032 14.3 0.3 0.19 11.8 0.1 2.2 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 THOC7 PF05615.13 CRJ93731.1 - 0.13 12.6 0.1 0.97 9.7 0.0 2.4 2 0 0 2 2 2 0 Tho complex subunit 7 Vps52 PF04129.12 CRJ93743.1 - 1.7e-125 419.7 0.2 2e-125 419.4 0.2 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.9 CRJ93743.1 - 3.2e-06 25.9 3.2 3.1e-05 22.6 3.2 2.0 1 1 0 1 1 1 1 Exocyst complex component Sec3 CENP-F_leu_zip PF10473.9 CRJ93743.1 - 0.089 12.8 0.4 0.55 10.2 0.1 2.3 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 THOC7 PF05615.13 CRJ93743.1 - 0.11 12.8 0.1 0.97 9.7 0.0 2.4 2 0 0 2 2 2 0 Tho complex subunit 7 Myb_DNA-binding PF00249.31 CRJ93751.1 - 0.0053 16.9 0.0 0.014 15.6 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 CRJ93751.1 - 0.021 14.7 0.0 0.05 13.5 0.0 1.6 1 0 0 1 1 1 0 Myb DNA-binding like Helicase_C PF00271.31 CRJ93760.1 - 5.8e-14 52.4 0.0 1.3e-13 51.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CRJ93760.1 - 3.8e-08 33.5 0.0 1.5e-06 28.3 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CRJ93760.1 - 0.00077 18.7 0.0 0.0013 17.9 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DEAD PF00270.29 CRJ93760.1 - 0.0079 16.0 0.0 0.24 11.1 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase KH_1 PF00013.29 CRJ93769.1 - 1.4e-29 101.7 4.1 1.6e-07 31.1 0.0 7.2 7 0 0 7 7 7 6 KH domain HAD_2 PF13419.6 CRJ93792.1 - 3.7e-10 40.2 0.0 6.2e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CRJ93792.1 - 1.7e-08 35.0 0.0 2.9e-08 34.3 0.0 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CRJ93792.1 - 1.2e-05 25.3 0.0 2.4e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Med21 PF11221.8 CRJ93805.1 - 2e-46 157.9 6.2 2.3e-46 157.7 6.2 1.0 1 0 0 1 1 1 1 Subunit 21 of Mediator complex GAS PF13851.6 CRJ93805.1 - 0.0012 18.2 3.1 0.36 10.2 0.0 2.1 2 0 0 2 2 2 2 Growth-arrest specific micro-tubule binding Med9 PF07544.13 CRJ93805.1 - 0.01 15.9 0.3 0.01 15.9 0.3 2.6 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 APG6_N PF17675.1 CRJ93805.1 - 0.015 15.8 6.0 0.04 14.4 6.0 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region HAUS-augmin3 PF14932.6 CRJ93805.1 - 0.061 12.9 5.1 1.6 8.3 1.1 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 COPI_assoc PF08507.10 CRJ93815.1 - 2.9e-31 108.2 6.6 3.9e-31 107.8 6.6 1.2 1 0 0 1 1 1 1 COPI associated protein DUF2583 PF10762.9 CRJ93815.1 - 0.13 12.7 6.1 1.8 9.0 0.0 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2583) MFS_MOT1 PF16983.5 CRJ93815.1 - 1.3 9.4 8.3 3 8.3 0.5 2.6 1 1 1 2 2 2 0 Molybdate transporter of MFS superfamily GATA PF00320.27 CRJ93828.1 - 8.3e-31 105.3 19.1 3.1e-16 58.7 4.5 2.5 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 CRJ93828.1 - 6.9e-07 28.7 5.3 0.0064 16.0 0.3 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding ArfGap PF01412.18 CRJ93828.1 - 0.00011 22.2 1.4 0.48 10.5 0.1 2.4 2 0 0 2 2 2 2 Putative GTPase activating protein for Arf Auto_anti-p27 PF06677.12 CRJ93828.1 - 0.0016 18.5 6.5 0.21 11.8 1.0 2.4 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) OrfB_Zn_ribbon PF07282.11 CRJ93828.1 - 0.0046 16.9 7.7 0.12 12.3 1.7 2.7 2 0 0 2 2 2 2 Putative transposase DNA-binding domain Zn-ribbon_8 PF09723.10 CRJ93828.1 - 0.0062 16.6 9.9 0.1 12.7 0.2 2.9 3 0 0 3 3 2 2 Zinc ribbon domain zf-RRN7 PF11781.8 CRJ93828.1 - 0.04 13.6 9.4 0.081 12.6 0.6 3.0 2 1 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 eIF-5_eIF-2B PF01873.17 CRJ93828.1 - 0.049 13.5 6.7 1.1 9.1 0.8 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Prim_Zn_Ribbon PF08273.12 CRJ93828.1 - 0.054 13.8 11.4 0.14 12.4 0.5 3.3 2 1 1 3 3 3 0 Zinc-binding domain of primase-helicase DZR PF12773.7 CRJ93828.1 - 2.3 8.3 14.5 7.1 6.7 1.7 3.1 1 1 1 2 2 2 0 Double zinc ribbon Rubredoxin_2 PF18073.1 CRJ93828.1 - 2.5 7.9 11.1 17 5.3 0.2 4.5 4 0 0 4 4 4 0 Rubredoxin metal binding domain A2L_zn_ribbon PF08792.10 CRJ93828.1 - 4 7.3 10.2 95 2.9 0.2 4.0 3 1 0 3 3 3 0 A2L zinc ribbon domain SAP PF02037.27 CRJ93840.1 - 8.3e-11 41.4 0.2 1.3e-10 40.7 0.2 1.3 1 0 0 1 1 1 1 SAP domain GATase PF00117.28 CRJ93845.1 - 3.5e-47 160.7 0.0 4.5e-47 160.3 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.22 CRJ93845.1 - 6.5e-32 110.1 0.0 1.2e-31 109.2 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.13 CRJ93845.1 - 2.2e-05 24.3 0.2 0.0037 17.0 0.1 2.6 1 1 1 2 2 2 2 Peptidase C26 ETF PF01012.21 CRJ93856.1 - 5.2e-44 150.3 0.5 8.7e-44 149.6 0.5 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain RRM_1 PF00076.22 CRJ93856.1 - 3e-30 103.8 0.1 1.6e-14 53.4 0.0 3.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CRJ93856.1 - 0.00036 20.6 0.0 0.12 12.5 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 CRJ93856.1 - 0.018 14.6 0.0 3.3 7.3 0.0 3.0 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tape_meas_lam_C PF09718.10 CRJ93856.1 - 0.24 11.6 1.8 0.47 10.6 0.1 2.2 2 0 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Flavodoxin_1 PF00258.25 CRJ93866.1 - 1.5e-31 109.6 0.0 2.5e-31 108.8 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.20 CRJ93866.1 - 8.1e-31 107.3 0.0 1.4e-30 106.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 CRJ93866.1 - 4.4e-13 49.8 0.0 1.6e-12 48.0 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_3 PF12641.7 CRJ93866.1 - 0.032 13.9 0.0 0.059 13.1 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin domain Flavodoxin_5 PF12724.7 CRJ93866.1 - 0.039 14.2 0.0 0.27 11.5 0.0 2.4 2 1 1 3 3 3 0 Flavodoxin domain Asp PF00026.23 CRJ93875.1 - 1.2e-12 47.9 1.8 7.3e-12 45.3 1.8 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Adeno_E3_CR2 PF02439.15 CRJ93875.1 - 0.017 14.9 0.4 0.03 14.1 0.4 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF2681 PF10883.8 CRJ93875.1 - 0.39 11.2 1.5 1.2 9.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) TAXi_N PF14543.6 CRJ93875.1 - 0.73 10.0 4.8 2.2 8.5 0.0 3.5 4 0 0 4 4 4 0 Xylanase inhibitor N-terminal GCP_N_terminal PF17681.1 CRJ94104.1 - 3.2e-22 79.6 0.0 3.2e-22 79.5 0.0 1.1 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal DUF4187 PF13821.6 CRJ94163.1 - 0.0017 18.1 0.1 0.0017 18.1 0.1 2.0 2 1 1 3 3 3 1 Domain of unknown function (DUF4187) HSP70 PF00012.20 CRJ94303.1 - 1.6e-20 72.8 1.0 1.7e-20 72.7 1.0 1.0 1 0 0 1 1 1 1 Hsp70 protein Radial_spoke_3 PF06098.11 CRJ94303.1 - 0.019 14.3 0.8 0.019 14.3 0.8 1.0 1 0 0 1 1 1 0 Radial spoke protein 3 NIR_SIR_ferr PF03460.17 CRJ94303.1 - 0.057 13.3 0.1 0.075 12.9 0.1 1.2 1 0 0 1 1 1 0 Nitrite/Sulfite reductase ferredoxin-like half domain DUF4972 PF16342.5 CRJ94303.1 - 0.06 13.0 0.6 0.072 12.8 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4972) ICL PF00463.21 CRJ94401.1 - 3.5e-41 141.3 0.0 3.8e-41 141.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family Hexapep PF00132.24 CRJ94507.1 - 2.6e-08 33.3 5.6 1.4e-06 27.8 1.1 2.6 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 CRJ94507.1 - 0.0014 18.4 0.6 0.24 11.2 0.3 2.3 1 1 1 2 2 2 2 Hexapeptide repeat of succinyl-transferase Chitin_synth_1 PF01644.17 CRJ94514.1 - 4e-38 131.0 0.0 5e-38 130.6 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Flavoprotein PF02441.19 CRJ94514.1 - 0.056 13.2 0.0 0.073 12.8 0.0 1.3 1 0 0 1 1 1 0 Flavoprotein CKS PF01111.19 CRJ94652.1 - 2.3e-18 66.2 0.2 3.7e-18 65.6 0.2 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit VWA PF00092.28 CRJ94799.1 - 0.014 15.6 0.0 0.031 14.5 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain VWA_2 PF13519.6 CRJ94799.1 - 0.08 13.6 0.1 0.2 12.3 0.0 1.8 2 0 0 2 2 2 0 von Willebrand factor type A domain AAA_8 PF12780.7 CRJ94949.1 - 6.6e-18 65.0 0.0 1.8e-11 43.9 0.0 2.3 1 1 1 2 2 2 2 P-loop containing dynein motor region D4 DHC_N2 PF08393.13 CRJ94949.1 - 2.5e-07 30.1 1.1 2.5e-07 30.1 1.1 1.7 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 DUF1664 PF07889.12 CRJ94949.1 - 0.0062 16.6 0.7 2.6 8.1 0.0 2.4 1 1 0 2 2 2 2 Protein of unknown function (DUF1664) COG2 PF06148.11 CRJ94949.1 - 0.0097 16.0 0.1 0.19 11.8 0.0 2.4 1 1 2 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF3755 PF12579.8 CRJ94949.1 - 0.04 13.6 0.1 0.19 11.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3755) DUF2894 PF11445.8 CRJ94949.1 - 0.071 13.6 0.2 0.13 12.8 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2894) NPV_P10 PF05531.12 CRJ94949.1 - 0.09 13.3 0.6 9.6 6.8 0.1 2.7 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein PilJ PF13675.6 CRJ94949.1 - 0.31 11.1 1.4 1.7 8.7 0.8 2.3 1 1 2 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Roc PF08477.13 CRJ95088.1 - 4.7e-10 39.7 0.0 5.3e-10 39.6 0.0 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CRJ95088.1 - 2.3e-09 37.1 0.1 2.5e-09 36.9 0.1 1.0 1 0 0 1 1 1 1 Ras family Arf PF00025.21 CRJ95088.1 - 0.01 15.3 0.0 0.01 15.3 0.0 1.0 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_7 PF12775.7 CRJ95088.1 - 0.08 12.4 0.0 0.08 12.4 0.0 1.0 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 CRJ95088.1 - 0.13 11.7 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Bacterial TniB protein SRPRB PF09439.10 CRJ95088.1 - 0.14 11.6 0.0 0.14 11.6 0.0 1.0 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 CRJ95088.1 - 0.18 12.2 0.0 0.19 12.1 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain Penaeidin PF05927.11 CRJ95231.1 - 0.82 10.5 2.4 1.3 9.8 0.2 1.9 1 1 1 2 2 2 0 Penaeidin CN_hydrolase PF00795.22 CRJ95238.1 - 7.4e-44 150.0 0.0 1.2e-43 149.3 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase TAF4 PF05236.14 CRJ95238.1 - 6.2e-20 72.1 2.8 6.4e-19 68.8 1.2 3.1 3 0 0 3 3 3 2 Transcription initiation factor TFIID component TAF4 family CPSF73-100_C PF11718.8 CRJ95256.1 - 1.8e-80 269.6 0.0 2.6e-80 269.0 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 CRJ95256.1 - 1.1e-29 102.9 0.0 2.2e-29 102.0 0.0 1.5 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_6 PF16661.5 CRJ95256.1 - 4.1e-12 45.9 0.1 7.1e-12 45.1 0.1 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 CRJ95256.1 - 6.8e-12 45.1 0.0 1.4e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 CRJ95256.1 - 2.2e-06 27.8 0.1 4.9e-06 26.7 0.1 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Beta_lactamase3 PF17030.5 CRJ95256.1 - 0.038 13.2 0.0 0.066 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative beta-lactamase-like family V_ATPase_I PF01496.19 CRJ95265.1 - 0 1042.2 0.0 0 1042.2 0.0 1.3 2 0 0 2 2 2 1 V-type ATPase 116kDa subunit family CHD5 PF04420.14 CRJ95265.1 - 5.5e-58 195.3 3.6 6.8e-58 195.0 0.4 2.6 2 1 0 2 2 2 1 CHD5-like protein DUF1515 PF07439.11 CRJ95265.1 - 0.017 15.2 4.3 1.6 8.8 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1515) WXG100 PF06013.12 CRJ95265.1 - 0.044 14.0 12.6 0.035 14.4 2.5 3.5 4 0 0 4 4 4 0 Proteins of 100 residues with WXG DUF3552 PF12072.8 CRJ95265.1 - 0.19 11.1 2.0 5 6.5 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) Baculo_PEP_C PF04513.12 CRJ95265.1 - 3.4 7.7 6.9 2.5 8.1 1.4 3.1 3 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus CheZ PF04344.13 CRJ95265.1 - 8.5 6.2 11.2 0.84 9.5 0.1 3.1 3 0 0 3 3 3 0 Chemotaxis phosphatase, CheZ Amidase PF01425.21 CRJ95277.1 - 5.7e-91 305.7 0.0 9.1e-91 305.1 0.0 1.3 1 0 0 1 1 1 1 Amidase CPSase_L_D2 PF02786.17 CRJ95277.1 - 8.7e-64 214.9 0.2 1.6e-63 214.0 0.2 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Asp PF00026.23 CRJ95277.1 - 1.7e-62 211.6 2.9 2.5e-62 211.1 2.9 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Biotin_carb_N PF00289.22 CRJ95277.1 - 8.4e-41 139.0 0.5 2e-39 134.5 0.0 2.7 3 0 0 3 3 3 1 Biotin carboxylase, N-terminal domain Dala_Dala_lig_C PF07478.13 CRJ95277.1 - 9.1e-12 44.9 0.0 1.7e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus TAXi_N PF14543.6 CRJ95277.1 - 3.5e-09 37.1 0.9 4.3e-07 30.3 0.9 2.6 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal ATP-grasp PF02222.22 CRJ95277.1 - 0.00029 20.5 0.1 0.00098 18.7 0.1 1.8 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.14 CRJ95277.1 - 0.0008 19.5 0.0 0.0016 18.5 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.6 CRJ95277.1 - 0.026 14.3 0.0 0.057 13.2 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon Asp_protease_2 PF13650.6 CRJ95277.1 - 0.052 14.2 0.0 1.1 10.0 0.0 2.9 2 1 0 2 2 2 0 Aspartyl protease V_ATPase_I PF01496.19 CRJ95287.1 - 2.6e-30 105.1 0.5 4e-30 104.5 0.5 1.3 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family CHD5 PF04420.14 CRJ95287.1 - 1.9e-24 86.4 0.2 3.9e-24 85.3 0.2 1.6 1 0 0 1 1 1 1 CHD5-like protein WXG100 PF06013.12 CRJ95287.1 - 0.013 15.7 1.3 0.013 15.7 1.3 3.1 3 0 0 3 3 3 0 Proteins of 100 residues with WXG CheZ PF04344.13 CRJ95287.1 - 0.058 13.3 2.8 0.12 12.3 0.2 2.2 2 0 0 2 2 2 0 Chemotaxis phosphatase, CheZ DUF1515 PF07439.11 CRJ95287.1 - 0.065 13.3 6.6 0.34 11.0 0.2 2.9 2 1 0 3 3 3 0 Protein of unknown function (DUF1515) ACT PF01842.25 CRJ95287.1 - 0.14 12.0 0.0 0.42 10.4 0.0 1.8 1 0 0 1 1 1 0 ACT domain Nup54 PF13874.6 CRJ95287.1 - 0.31 11.2 3.9 2.6 8.1 0.3 2.4 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 FAM184 PF15665.5 CRJ95287.1 - 0.76 9.5 6.3 0.57 9.9 1.7 2.3 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B DivIC PF04977.15 CRJ95287.1 - 1.6 8.5 6.8 0.37 10.6 0.7 2.7 3 0 0 3 3 3 0 Septum formation initiator PPTA PF01239.22 CRJ95296.1 - 7.1e-09 35.1 15.2 0.00015 21.3 0.5 4.5 5 0 0 5 5 5 3 Protein prenyltransferase alpha subunit repeat TEP1_N PF05386.11 CRJ95296.1 - 0.35 10.5 1.2 0.75 9.4 0.1 2.1 3 0 0 3 3 3 0 TEP1 N-terminal domain CT_A_B PF02626.15 CRJ95304.1 - 3.6e-76 256.3 0.1 2e-66 224.3 0.0 2.9 2 1 1 3 3 3 2 Carboxyltransferase domain, subdomain A and B Amidase PF01425.21 CRJ95304.1 - 1.3e-72 245.2 0.2 2.1e-72 244.5 0.2 1.2 1 0 0 1 1 1 1 Amidase Asp PF00026.23 CRJ95304.1 - 4.9e-63 213.5 3.5 7.4e-63 212.9 3.5 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease CT_C_D PF02682.16 CRJ95304.1 - 2.8e-36 125.1 0.0 9.5e-36 123.4 0.0 1.8 2 0 0 2 2 2 1 Carboxyltransferase domain, subdomain C and D Biotin_carb_C PF02785.19 CRJ95304.1 - 2.6e-33 114.3 0.0 5.7e-33 113.3 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 CRJ95304.1 - 2e-12 46.8 0.3 4.7e-12 45.6 0.3 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme TAXi_N PF14543.6 CRJ95304.1 - 3.5e-09 37.1 0.9 5e-07 30.1 0.9 2.8 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Biotin_lipoyl_2 PF13533.6 CRJ95304.1 - 1e-06 28.5 0.0 0.011 15.6 0.0 2.9 1 1 1 2 2 2 2 Biotin-lipoyl like RnfC_N PF13375.6 CRJ95304.1 - 0.03 14.3 0.0 0.079 12.9 0.0 1.6 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain GCV_H PF01597.19 CRJ95304.1 - 0.068 13.1 0.1 0.19 11.6 0.1 1.7 2 0 0 2 2 2 0 Glycine cleavage H-protein DUF2118 PF09891.9 CRJ95304.1 - 0.069 13.1 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) NQRA PF05896.11 CRJ95304.1 - 0.11 11.8 0.1 0.21 11.0 0.1 1.3 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) Asp_protease_2 PF13650.6 CRJ95304.1 - 0.11 13.1 0.1 2.5 8.8 0.0 3.0 2 0 0 2 2 2 0 Aspartyl protease CT_C_D PF02682.16 CRJ95311.1 - 2.1e-16 60.3 0.7 3.8e-15 56.2 0.1 2.1 2 0 0 2 2 2 1 Carboxyltransferase domain, subdomain C and D Biotin_lipoyl PF00364.22 CRJ95311.1 - 4.1e-13 49.0 0.3 6.4e-13 48.3 0.3 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 CRJ95311.1 - 1.5e-07 31.1 0.1 0.0014 18.4 0.0 2.4 1 1 1 2 2 2 2 Biotin-lipoyl like RnfC_N PF13375.6 CRJ95311.1 - 0.0024 17.8 0.0 0.0043 17.0 0.0 1.3 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain HlyD_D23 PF16576.5 CRJ95311.1 - 0.0067 15.7 0.0 0.46 9.7 0.0 2.6 2 1 1 3 3 3 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion GCV_H PF01597.19 CRJ95311.1 - 0.0076 16.1 0.1 0.026 14.4 0.1 1.8 2 0 0 2 2 2 1 Glycine cleavage H-protein PTS_EIIA_1 PF00358.20 CRJ95311.1 - 0.015 15.1 0.0 0.27 11.0 0.0 2.5 2 1 1 3 3 3 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 NQRA PF05896.11 CRJ95311.1 - 0.025 14.0 0.2 0.059 12.8 0.1 1.6 2 0 0 2 2 2 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) DUF2118 PF09891.9 CRJ95311.1 - 0.029 14.3 0.1 0.047 13.6 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) HlyD_3 PF13437.6 CRJ95311.1 - 0.093 13.4 0.1 0.48 11.1 0.0 2.1 1 1 1 2 2 2 0 HlyD family secretion protein Fungal_trans PF04082.18 CRJ95321.1 - 7e-21 74.4 0.0 9.6e-21 74.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRJ95321.1 - 9.9e-05 22.4 8.0 0.00016 21.7 8.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lar_restr_allev PF14354.6 CRJ95321.1 - 0.29 11.6 3.1 0.56 10.6 3.1 1.5 1 0 0 1 1 1 0 Restriction alleviation protein Lar PAD PF03068.15 CRJ95332.1 - 2e-113 379.3 0.0 2.7e-113 378.9 0.0 1.1 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) PAD_M PF08527.10 CRJ95332.1 - 0.019 14.6 0.4 0.042 13.5 0.4 1.5 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) middle domain DUF948 PF06103.11 CRJ95332.1 - 0.1 12.8 0.0 3.6 7.9 0.0 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Fungal_trans PF04082.18 CRJ95341.1 - 1.6e-21 76.6 0.0 2e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain PAD PF03068.15 CRJ95350.1 - 7.3e-115 384.1 0.0 1.1e-114 383.5 0.0 1.2 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) zinc_ribbon_2 PF13240.6 CRJ95361.1 - 0.00071 19.2 1.6 0.0014 18.3 1.6 1.5 1 0 0 1 1 1 1 zinc-ribbon domain zf-ribbon_3 PF13248.6 CRJ95361.1 - 0.005 16.2 4.1 0.012 15.0 4.1 1.7 1 0 0 1 1 1 1 zinc-ribbon domain DUF922 PF06037.11 CRJ95361.1 - 0.0071 16.2 0.3 0.012 15.4 0.3 1.3 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF922) DZR PF12773.7 CRJ95361.1 - 0.014 15.4 8.4 0.035 14.1 8.4 1.8 1 1 0 1 1 1 0 Double zinc ribbon UPF0547 PF10571.9 CRJ95361.1 - 0.036 14.1 2.8 0.071 13.2 2.8 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 DUF2116 PF09889.9 CRJ95361.1 - 0.14 12.2 2.6 0.29 11.2 2.6 1.5 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) zf-RanBP PF00641.18 CRJ95361.1 - 0.15 11.4 5.6 0.36 10.2 5.6 1.7 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others zinc-ribbon_6 PF10005.9 CRJ95361.1 - 0.27 11.9 3.8 0.71 10.6 3.8 1.7 1 1 0 1 1 1 0 zinc-ribbon domain Ras PF00071.22 CRJ95366.1 - 1.6e-56 190.4 0.0 1.8e-56 190.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CRJ95366.1 - 7.2e-22 77.9 0.0 1e-21 77.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CRJ95366.1 - 9.3e-07 28.5 0.0 1.5e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 CRJ95366.1 - 0.004 16.6 0.0 0.0054 16.2 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit baeRF_family3 PF18845.1 CRJ95366.1 - 0.095 13.0 0.0 0.34 11.2 0.0 1.8 1 1 1 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 3 NB-ARC PF00931.22 CRJ95366.1 - 0.13 11.4 0.1 1.7 7.8 0.0 2.0 1 1 0 2 2 2 0 NB-ARC domain Skp1 PF01466.19 CRJ95366.1 - 0.14 12.3 0.7 0.76 9.9 0.1 2.4 3 0 0 3 3 3 0 Skp1 family, dimerisation domain Gtr1_RagA PF04670.12 CRJ95366.1 - 0.16 11.3 0.0 0.2 11.0 0.0 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region IKI3 PF04762.12 CRJ95381.1 - 1.1e-146 490.4 0.1 2.9e-146 488.9 0.1 1.6 2 0 0 2 2 2 1 IKI3 family IKI3 PF04762.12 CRJ95396.1 - 0 1014.8 0.0 0 1014.1 0.0 1.3 2 0 0 2 2 2 1 IKI3 family ANAPC4_WD40 PF12894.7 CRJ95396.1 - 6.6e-05 23.1 0.3 11 6.5 0.0 5.0 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DUF3984 PF13136.6 CRJ95403.1 - 4.1e-83 279.5 35.1 7.8e-62 209.6 23.7 4.7 3 2 0 3 3 3 3 Protein of unknown function (DUF3984) Hpt PF01627.23 CRJ95419.1 - 8.5e-12 45.2 0.2 2.5e-11 43.7 0.1 1.9 2 1 0 2 2 2 1 Hpt domain AKAP7_NLS PF10469.9 CRJ95428.1 - 6e-16 59.0 0.0 1.1e-15 58.0 0.0 1.5 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain Hpt PF01627.23 CRJ95428.1 - 1.2e-10 41.5 1.2 2.4e-10 40.5 0.1 2.2 2 0 0 2 2 2 1 Hpt domain DLIC PF05783.11 CRJ95428.1 - 5.7 5.6 7.2 0.37 9.6 0.3 2.0 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) AKAP7_NLS PF10469.9 CRJ95439.1 - 1.6e-24 87.0 0.0 2.5e-24 86.3 0.0 1.3 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain HSP70 PF00012.20 CRJ95449.1 - 1.3e-12 46.7 0.0 1.8e-11 43.0 0.0 2.0 2 0 0 2 2 2 2 Hsp70 protein FtsA PF14450.6 CRJ95449.1 - 0.00084 19.7 0.0 0.018 15.5 0.0 2.5 2 0 0 2 2 2 1 Cell division protein FtsA Diphthamide_syn PF01866.17 CRJ95461.1 - 1.8e-71 241.1 0.0 2.4e-71 240.7 0.0 1.2 1 0 0 1 1 1 1 Putative diphthamide synthesis protein HSP70 PF00012.20 CRJ95467.1 - 3.4e-12 45.3 0.1 3.7e-11 41.9 0.0 1.9 2 0 0 2 2 2 2 Hsp70 protein FtsA PF14450.6 CRJ95467.1 - 0.0016 18.8 0.0 0.026 14.9 0.0 2.4 2 0 0 2 2 2 1 Cell division protein FtsA HSP70 PF00012.20 CRJ95477.1 - 1.1e-67 228.7 0.2 1.2e-67 228.4 0.2 1.0 1 0 0 1 1 1 1 Hsp70 protein HSP70 PF00012.20 CRJ95487.1 - 0 1280.9 16.8 4.6e-257 854.0 7.3 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 CRJ95487.1 - 4.3e-33 114.5 1.4 1.3e-15 57.0 0.0 4.1 4 0 0 4 4 4 4 MreB/Mbl protein StbA PF06406.11 CRJ95487.1 - 7.9e-06 25.3 0.0 0.14 11.4 0.0 2.4 2 0 0 2 2 2 2 StbA protein BcrAD_BadFG PF01869.20 CRJ95487.1 - 1.7e-05 24.4 0.1 0.84 9.1 0.0 3.3 3 0 0 3 3 3 2 BadF/BadG/BcrA/BcrD ATPase family Hydantoinase_A PF01968.18 CRJ95487.1 - 1.8e-05 24.2 1.6 0.11 11.7 0.1 2.7 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase DeoC PF01791.9 CRJ95487.1 - 4.4e-05 23.2 1.4 2.9 7.4 0.0 4.1 4 0 0 4 4 4 2 DeoC/LacD family aldolase FtsA PF14450.6 CRJ95487.1 - 0.00025 21.4 4.0 7.4 7.1 0.0 4.7 5 0 0 5 5 5 2 Cell division protein FtsA FGGY_C PF02782.16 CRJ95487.1 - 0.0039 16.9 0.0 0.011 15.5 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 CRJ95487.1 - 0.0073 15.3 0.7 6.6 5.6 0.1 3.0 3 0 0 3 3 3 2 Diol dehydratase reactivase ATPase-like domain Amdo_NSP PF12475.8 CRJ95487.1 - 0.0081 16.2 0.0 7.7 6.7 0.0 2.6 2 0 0 2 2 2 2 Amdovirus non-structural protein Pox_D5 PF03288.16 CRJ95487.1 - 0.0093 16.4 0.2 8.6 6.9 0.0 2.6 2 0 0 2 2 2 2 Poxvirus D5 protein-like DUF1894 PF08979.11 CRJ95487.1 - 0.023 15.0 0.0 18 5.8 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1894) Alginate_lyase2 PF08787.11 CRJ95487.1 - 0.065 13.1 0.0 18 5.1 0.0 3.5 2 2 2 4 4 4 0 Alginate lyase DUF3128 PF11326.8 CRJ95497.1 - 5.2e-27 94.0 4.3 5.2e-27 94.0 4.3 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3128) PHY PF00360.20 CRJ95497.1 - 0.0059 15.9 0.7 0.011 15.1 0.7 1.4 1 0 0 1 1 1 1 Phytochrome region RNA12 PF10443.9 CRJ95514.1 - 4.2e-122 408.1 4.9 1.3e-62 212.0 0.5 2.5 2 1 1 3 3 3 2 RNA12 protein RRM_1 PF00076.22 CRJ95514.1 - 1.2e-06 28.2 0.0 2.6e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATPase_2 PF01637.18 CRJ95514.1 - 0.0024 17.8 0.0 0.0065 16.4 0.0 1.7 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea DUF913 PF06025.12 CRJ95522.1 - 1.7e-128 428.7 0.0 1.7e-128 428.7 0.0 9.1 9 2 0 9 9 9 3 Domain of Unknown Function (DUF913) DUF908 PF06012.12 CRJ95522.1 - 2e-125 418.9 0.2 2e-125 418.9 0.2 4.3 4 1 0 4 4 4 1 Domain of Unknown Function (DUF908) HECT PF00632.25 CRJ95522.1 - 7.7e-93 311.3 0.1 1.3e-92 310.6 0.1 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) UBM PF14377.6 CRJ95522.1 - 3.9e-42 140.5 33.5 3.9e-08 32.5 0.2 6.0 5 0 0 5 5 5 5 Ubiquitin binding region Rtt106_N PF18215.1 CRJ95522.1 - 0.0019 17.9 0.0 5.7 6.8 0.0 3.5 2 0 0 2 2 2 2 Histone chaperone Rtt106 N-terminal domain UPF0730 PF15827.5 CRJ95522.1 - 0.12 12.1 0.0 25 4.7 0.0 2.5 2 0 0 2 2 2 0 UPF0730 unknown protein family DUF4770 PF15994.5 CRJ95522.1 - 1.3 9.2 11.0 8.8 6.5 1.5 3.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) Ribosomal_S6e PF01092.19 CRJ95537.1 - 3.6e-30 104.5 0.0 4.1e-30 104.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S6e DLH PF01738.18 CRJ95548.1 - 1.1e-17 64.3 0.1 2.3e-17 63.3 0.1 1.4 1 1 0 1 1 1 1 Dienelactone hydrolase family MS_channel PF00924.18 CRJ95557.1 - 5.4e-20 71.8 2.6 9.8e-20 71.0 2.6 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_5 PF13202.6 CRJ95557.1 - 0.011 15.2 0.2 0.035 13.6 0.2 1.8 1 0 0 1 1 1 0 EF hand EF-hand_1 PF00036.32 CRJ95557.1 - 0.027 14.0 0.2 0.084 12.5 0.2 1.8 1 0 0 1 1 1 0 EF hand E1-E2_ATPase PF00122.20 CRJ95557.1 - 8.5 5.8 6.6 1.2 8.7 0.6 2.2 2 0 0 2 2 2 0 E1-E2 ATPase Abp2 PF09441.10 CRJ95564.1 - 4.5e-83 277.4 0.0 7.7e-83 276.7 0.0 1.4 1 0 0 1 1 1 1 ARS binding protein 2 DFRP_C PF16543.5 CRJ95575.1 - 1e-22 80.4 3.5 1e-22 80.4 3.5 3.7 3 0 0 3 3 3 1 DRG Family Regulatory Proteins, Tma46 Sds3 PF08598.11 CRJ95575.1 - 5.1e-17 62.6 28.1 3e-11 43.7 5.6 3.5 2 1 2 4 4 4 2 Sds3-like Torus PF16131.5 CRJ95575.1 - 2.4e-06 28.2 10.7 4.9e-06 27.2 1.7 3.2 2 1 1 3 3 3 1 Torus domain zf-CCCH PF00642.24 CRJ95575.1 - 2.4e-05 24.1 1.1 2.4e-05 24.1 1.1 2.2 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CRJ95575.1 - 0.00033 20.6 6.7 0.00033 20.6 6.7 2.9 3 0 0 3 3 3 1 Zinc finger domain zf-CCCH_4 PF18044.1 CRJ95575.1 - 0.0014 18.4 8.9 0.0067 16.2 2.7 3.2 3 0 0 3 3 3 1 CCCH-type zinc finger zf-CCCH_3 PF15663.5 CRJ95575.1 - 0.018 15.3 0.4 0.41 10.9 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 CRJ95575.1 - 0.24 11.9 14.4 0.9 10.1 6.7 2.7 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger RNase_T PF00929.24 CRJ95575.1 - 3.9 8.0 7.5 8.7 6.9 0.4 3.0 3 0 0 3 3 3 0 Exonuclease SLAC1 PF03595.17 CRJ95585.1 - 1.4e-36 126.4 23.0 1.9e-36 126.0 23.0 1.1 1 0 0 1 1 1 1 Voltage-dependent anion channel COG5 PF10392.9 CRJ95585.1 - 0.00083 19.5 0.3 0.00083 19.5 0.3 2.2 3 0 0 3 3 3 1 Golgi transport complex subunit 5 Noggin PF05806.12 CRJ95585.1 - 0.057 13.3 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 Noggin DUF3974 PF13120.6 CRJ95585.1 - 0.18 11.9 0.1 0.36 11.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3974) COX2_TM PF02790.15 CRJ95602.1 - 0.013 15.7 0.0 0.013 15.6 0.0 1.1 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane domain DUF1206 PF06724.11 CRJ95602.1 - 0.032 14.3 0.3 0.04 14.0 0.3 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) OAD_gamma PF04277.13 CRJ95602.1 - 0.071 13.7 0.4 0.097 13.3 0.3 1.3 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Ribosomal_S5_C PF03719.15 CRJ95612.1 - 1.7e-20 72.2 0.1 4.5e-20 70.9 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 CRJ95612.1 - 4.8e-17 61.7 1.2 9.8e-17 60.7 0.1 2.0 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain DASH_Dad3 PF08656.10 CRJ95619.1 - 4.6e-33 113.1 0.5 5.5e-33 112.9 0.5 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad3 MetOD2 PF18548.1 CRJ95619.1 - 0.045 13.8 0.1 0.067 13.3 0.1 1.3 1 0 0 1 1 1 0 Metanogen output domain 2 Pkinase PF00069.25 CRJ95626.1 - 8.1e-75 251.6 0.0 1.1e-74 251.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRJ95626.1 - 1.8e-30 106.1 0.0 3.8e-22 78.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CRJ95626.1 - 2e-06 27.3 0.1 1.3 8.3 0.0 3.2 3 0 0 3 3 3 3 Kinase-like Pkinase_fungal PF17667.1 CRJ95626.1 - 0.012 14.4 0.0 0.022 13.5 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 CRJ95626.1 - 0.017 14.5 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CRJ95626.1 - 0.025 14.5 0.0 0.87 9.5 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family FOXP-CC PF16159.5 CRJ95633.1 - 0.00025 21.6 2.0 0.024 15.2 2.6 2.3 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 CRJ95633.1 - 0.04 14.0 0.0 0.056 13.6 0.0 1.1 1 0 0 1 1 1 0 Aberrant zinc-finger zf-C2H2_4 PF13894.6 CRJ95633.1 - 0.045 14.6 4.8 4.1 8.5 0.4 2.7 3 0 0 3 3 3 0 C2H2-type zinc finger AT_hook PF02178.19 CRJ95633.1 - 1.6 8.9 21.0 1 9.4 5.1 3.1 2 0 0 2 2 2 0 AT hook motif VCBS PF13517.6 CRJ95646.1 - 4.8e-78 257.7 110.5 1.6e-10 41.4 1.3 14.1 7 4 6 13 13 13 13 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TcdB_toxin_midN PF12256.8 CRJ95646.1 - 1.1e-25 90.0 46.1 0.96 8.8 0.1 18.0 8 4 9 18 18 18 14 Insecticide toxin TcdB middle/N-terminal region DFRP_C PF16543.5 CRJ95646.1 - 1.8e-25 89.3 8.4 1.8e-25 89.3 8.4 3.7 5 0 0 5 5 2 1 DRG Family Regulatory Proteins, Tma46 FG-GAP PF01839.23 CRJ95646.1 - 1.3e-19 70.0 113.6 0.076 13.2 0.4 18.9 18 0 0 18 18 18 11 FG-GAP repeat Lipase_GDSL_2 PF13472.6 CRJ95646.1 - 3.4e-15 56.9 0.7 1.1e-14 55.3 0.7 1.9 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family CS PF04969.16 CRJ95646.1 - 4.4e-13 50.1 0.1 1.7e-07 32.2 0.1 2.5 2 0 0 2 2 2 2 CS domain BBS2_Mid PF14783.6 CRJ95646.1 - 1.1e-06 28.7 3.0 4.3 7.4 0.0 6.4 7 2 0 7 7 5 3 Ciliary BBSome complex subunit 2, middle region Torus PF16131.5 CRJ95646.1 - 2.6e-06 28.1 7.0 1.4e-05 25.7 1.5 3.0 1 1 1 2 2 2 1 Torus domain Lipase_GDSL PF00657.22 CRJ95646.1 - 6e-06 26.4 0.1 1.3e-05 25.3 0.1 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase PliI PF16743.5 CRJ95646.1 - 7.1e-06 25.8 15.2 5.7 6.7 0.0 11.2 11 4 6 17 17 17 2 Periplasmic lysozyme inhibitor of I-type lysozyme zf-CCCH PF00642.24 CRJ95646.1 - 3.1e-05 23.8 1.1 8.1e-05 22.4 1.1 1.8 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Dockerin_1 PF00404.18 CRJ95646.1 - 0.00012 22.2 52.6 2.3 8.5 0.2 15.3 16 2 2 18 18 18 2 Dockerin type I domain zf_CCCH_4 PF18345.1 CRJ95646.1 - 0.0011 19.0 6.7 0.0011 19.0 6.7 2.9 3 0 0 3 3 3 1 Zinc finger domain WD40 PF00400.32 CRJ95646.1 - 0.0048 17.7 7.2 6.5 7.8 0.2 4.8 4 0 0 4 4 4 2 WD domain, G-beta repeat S4_2 PF13275.6 CRJ95646.1 - 0.0058 16.4 0.1 7.3 6.5 0.0 3.2 2 0 0 2 2 2 2 S4 domain zf-CCCH_4 PF18044.1 CRJ95646.1 - 0.029 14.2 8.9 0.022 14.6 2.7 2.9 3 0 0 3 3 3 0 CCCH-type zinc finger Itfg2 PF15907.5 CRJ95646.1 - 0.042 12.9 16.3 0.84 8.6 0.2 8.0 6 2 2 9 9 9 0 Integrin-alpha FG-GAP repeat-containing protein 2 zf-CCCH_2 PF14608.6 CRJ95646.1 - 0.75 10.4 12.8 3 8.5 6.7 2.8 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger RRM_1 PF00076.22 CRJ95654.1 - 1.3e-15 57.0 0.0 2e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 CRJ95654.1 - 0.00018 22.0 2.5 0.00018 22.0 2.5 2.8 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 RRM_occluded PF16842.5 CRJ95654.1 - 0.0016 18.3 0.0 0.003 17.4 0.0 1.5 1 0 0 1 1 1 1 Occluded RNA-recognition motif Peptidase_M35 PF02102.15 CRJ95654.1 - 0.045 12.6 3.5 0.074 11.9 3.5 1.3 1 0 0 1 1 1 0 Deuterolysin metalloprotease (M35) family Limkain-b1 PF11608.8 CRJ95654.1 - 0.053 13.6 0.1 0.17 11.9 0.1 1.9 1 1 0 1 1 1 0 Limkain b1 DUF5102 PF17104.5 CRJ95654.1 - 0.24 11.4 2.1 0.28 11.2 0.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5102) FGF-BP1 PF06473.12 CRJ95654.1 - 3.6 7.3 6.3 6.6 6.5 2.4 2.1 2 0 0 2 2 2 0 FGF binding protein 1 (FGF-BP1) FOXP-CC PF16159.5 CRJ95675.1 - 0.052 14.2 0.5 0.1 13.2 0.5 1.4 1 0 0 1 1 1 0 FOXP coiled-coil domain AT_hook PF02178.19 CRJ95675.1 - 0.82 9.8 21.0 0.7 10.0 5.1 3.0 2 0 0 2 2 2 0 AT hook motif adh_short PF00106.25 CRJ95682.1 - 6.4e-21 74.7 0.0 1.4e-20 73.5 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRJ95682.1 - 2.1e-15 56.9 0.0 4.1e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase RRM_1 PF00076.22 CRJ95682.1 - 3e-15 55.8 0.0 5.8e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 CRJ95682.1 - 0.00051 20.5 2.5 0.00051 20.5 2.5 3.2 3 1 1 4 4 4 1 C-terminal duplication domain of Friend of PRMT1 RRM_occluded PF16842.5 CRJ95682.1 - 0.0047 16.8 0.0 0.0098 15.7 0.0 1.5 1 0 0 1 1 1 1 Occluded RNA-recognition motif KR PF08659.10 CRJ95682.1 - 0.029 14.3 0.0 0.059 13.3 0.0 1.5 1 0 0 1 1 1 0 KR domain Limkain-b1 PF11608.8 CRJ95682.1 - 0.12 12.4 0.0 0.42 10.7 0.0 2.0 1 1 0 1 1 1 0 Limkain b1 Cwf_Cwc_15 PF04889.12 CRJ95694.1 - 0.00097 18.9 4.8 0.001 18.9 4.8 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein COPI_C PF06957.11 CRJ95694.1 - 0.34 9.6 2.7 0.35 9.6 2.7 1.0 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Lipase_GDSL_2 PF13472.6 CRJ95706.1 - 9.9e-16 58.6 0.7 2.1e-15 57.6 0.7 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family VCBS PF13517.6 CRJ95706.1 - 5.1e-10 39.8 9.2 2e-09 37.9 9.2 2.1 1 0 0 1 1 1 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Lipase_GDSL PF00657.22 CRJ95706.1 - 1.9e-05 24.7 0.1 3.5e-05 23.9 0.1 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase FG-GAP PF01839.23 CRJ95706.1 - 1.3 9.3 10.9 1.5 9.0 0.8 3.0 2 0 0 2 2 2 0 FG-GAP repeat Peptidase_M14 PF00246.24 CRJ95719.1 - 2.5e-15 57.1 0.0 3.7e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 CRJ95719.1 - 0.004 16.3 0.3 0.014 14.5 0.3 1.9 1 1 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family Isochorismatase PF00857.20 CRJ95727.1 - 1.1e-15 58.3 0.0 1.8e-15 57.6 0.0 1.3 1 0 0 1 1 1 1 Isochorismatase family Isochorismatase PF00857.20 CRJ95733.1 - 2.8e-15 57.0 0.0 4.9e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 Isochorismatase family GFA PF04828.14 CRJ95741.1 - 6e-17 61.8 3.0 6.3e-14 52.1 0.0 2.2 2 0 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme gp12-short_mid PF09089.10 CRJ95755.1 - 0.051 13.7 0.1 0.068 13.3 0.1 1.2 1 0 0 1 1 1 0 Phage short tail fibre protein gp12, middle domain Ras PF00071.22 CRJ95762.1 - 1.8e-15 56.9 0.0 1.3e-12 47.6 0.0 2.0 2 0 0 2 2 2 2 Ras family Roc PF08477.13 CRJ95762.1 - 0.00097 19.3 0.1 0.61 10.3 0.0 2.2 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 CRJ95762.1 - 0.025 13.8 0.0 0.026 13.7 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit RNA_pol_Rpb4 PF03874.16 CRJ95769.1 - 1.8e-20 73.5 0.0 2.1e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 Polysacc_deac_2 PF04748.13 CRJ95769.1 - 0.094 11.9 0.0 0.2 10.8 0.0 1.5 1 1 0 1 1 1 0 Divergent polysaccharide deacetylase Glyco_transf_54 PF04666.13 CRJ95769.1 - 0.16 10.8 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Pribosyl_synth PF14572.6 CRJ95776.1 - 1.8e-40 138.9 1.3 8.2e-34 117.2 0.4 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 CRJ95776.1 - 1.1e-30 105.9 0.0 3.9e-30 104.2 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 CRJ95776.1 - 2.4e-17 62.9 0.1 4.1e-17 62.1 0.1 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CRJ95776.1 - 0.00055 19.4 0.1 0.00092 18.7 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase UQ_con PF00179.26 CRJ95786.1 - 6.7e-07 29.0 0.0 1.3e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CRJ95786.1 - 0.091 12.5 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic E2 family B PseudoU_synth_1 PF01416.20 CRJ95793.1 - 1.8e-71 237.4 0.0 8.8e-30 103.4 0.0 4.4 3 1 1 4 4 4 3 tRNA pseudouridine synthase Ras PF00071.22 CRJ95800.1 - 3.8e-16 59.1 0.0 1.3e-15 57.4 0.0 1.7 1 1 0 1 1 1 1 Ras family Roc PF08477.13 CRJ95800.1 - 0.00013 22.1 0.1 0.087 13.1 0.0 2.2 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CRJ95800.1 - 0.0031 17.0 0.1 0.32 10.4 0.0 2.0 2 0 0 2 2 2 2 ADP-ribosylation factor family SRPRB PF09439.10 CRJ95800.1 - 0.17 11.3 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit G-alpha PF00503.20 CRJ95800.1 - 0.19 10.9 0.0 0.28 10.3 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit RNA_pol_Rpb4 PF03874.16 CRJ95807.1 - 1.3e-16 61.0 0.1 1.5e-16 60.9 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb4 Polysacc_deac_2 PF04748.13 CRJ95807.1 - 0.062 12.5 0.0 0.11 11.7 0.0 1.3 1 1 0 1 1 1 0 Divergent polysaccharide deacetylase Glyco_transf_54 PF04666.13 CRJ95807.1 - 0.098 11.5 0.0 0.12 11.2 0.0 1.0 1 0 0 1 1 1 0 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Pribosyl_synth PF14572.6 CRJ95812.1 - 1.7e-41 142.3 1.4 7.5e-35 120.6 0.4 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 CRJ95812.1 - 1.1e-30 106.0 0.0 3.7e-30 104.2 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 CRJ95812.1 - 3.1e-18 65.8 0.2 5.2e-18 65.1 0.2 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CRJ95812.1 - 0.00048 19.6 0.1 0.00082 18.9 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PARP PF00644.20 CRJ95819.1 - 1.6e-10 40.9 1.4 7e-10 38.8 0.4 2.1 1 1 1 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.26 CRJ95819.1 - 2.1e-07 30.7 0.0 4.2e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme TnsE_C PF18623.1 CRJ95819.1 - 0.14 12.1 0.0 8.4 6.3 0.0 2.4 2 0 0 2 2 2 0 TnsE C-terminal domain Slu7 PF11708.8 CRJ95819.1 - 0.28 10.9 0.3 0.44 10.3 0.3 1.2 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor DUF5572 PF17733.1 CRJ95826.1 - 1.4e-14 53.6 0.2 3.4e-14 52.4 0.2 1.7 1 0 0 1 1 1 1 Family of unknown function (DUF5572) PUF PF00806.19 CRJ95833.1 - 2.8e-40 133.8 0.1 2.1e-06 27.1 0.0 8.9 9 0 0 9 9 9 7 Pumilio-family RNA binding repeat MRP-S33 PF08293.11 CRJ95833.1 - 1.5e-23 82.9 0.0 3.8e-23 81.5 0.0 1.7 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 LIF_OSM PF01291.17 CRJ95833.1 - 0.14 12.3 0.2 0.25 11.4 0.2 1.4 1 0 0 1 1 1 0 LIF / OSM family ATG16 PF08614.11 CRJ95833.1 - 2.8 8.1 5.4 6 7.0 5.4 1.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF1688 PF07958.11 CRJ95844.1 - 2.3e-172 573.4 0.0 2.6e-172 573.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) Q_salvage PF10343.9 CRJ95844.1 - 3.3e-05 23.6 0.0 0.2 11.2 0.0 2.1 2 0 0 2 2 2 2 Potential Queuosine, Q, salvage protein family Ribonuclease_T2 PF00445.18 CRJ95853.1 - 1.3e-39 136.3 5.6 2e-39 135.7 5.6 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family Molybdopterin PF00384.22 CRJ95858.1 - 1.1e-73 248.7 0.0 8.8e-72 242.4 0.0 2.1 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.6 CRJ95858.1 - 4.6e-21 74.6 0.3 3.1e-20 72.0 0.2 2.5 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain NADH_dhqG_C PF09326.11 CRJ95858.1 - 8.1e-18 64.9 0.0 2.1e-17 63.5 0.0 1.8 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal Fer2 PF00111.27 CRJ95858.1 - 2.6e-09 36.9 0.5 4.9e-09 36.0 0.5 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 CRJ95858.1 - 0.00016 21.1 0.0 0.00016 21.1 0.0 2.2 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Lyx_isomer PF07385.12 CRJ95858.1 - 0.055 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 D-lyxose isomerase TPP_enzyme_M PF00205.22 CRJ95858.1 - 0.062 13.0 0.0 0.2 11.4 0.0 1.8 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Fer4_19 PF06902.11 CRJ95858.1 - 0.11 12.6 0.2 22 5.2 0.1 2.5 2 0 0 2 2 2 0 Divergent 4Fe-4S mono-cluster Fer4 PF00037.27 CRJ95858.1 - 0.12 12.2 1.1 3.4 7.6 0.3 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain UPF0061 PF02696.14 CRJ95868.1 - 2.5e-90 303.5 0.0 1.5e-72 244.9 0.0 3.0 1 1 2 3 3 3 3 Uncharacterized ACR, YdiU/UPF0061 family Lipocalin_5 PF13924.6 CRJ95876.1 - 5.9e-29 100.7 0.0 6.7e-29 100.5 0.0 1.0 1 0 0 1 1 1 1 Lipocalin-like domain DUF4774 PF15999.5 CRJ95876.1 - 0.0011 18.7 0.8 0.0021 17.8 0.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4774) Aldo_ket_red PF00248.21 CRJ95882.1 - 2.9e-40 138.3 0.0 1.2e-34 119.9 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family B12-binding PF02310.19 CRJ95882.1 - 0.068 13.2 0.0 0.22 11.6 0.0 1.8 2 0 0 2 2 2 0 B12 binding domain XRCC4 PF06632.12 CRJ95888.1 - 2.2e-08 33.3 0.8 2.2e-08 33.3 0.8 2.0 1 1 1 2 2 2 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 Snapin_Pallidin PF14712.6 CRJ95888.1 - 0.003 18.0 2.0 0.0092 16.4 1.3 2.0 2 0 0 2 2 2 1 Snapin/Pallidin BUD22 PF09073.10 CRJ95888.1 - 0.1 11.9 21.1 0.16 11.3 21.1 1.3 1 0 0 1 1 1 0 BUD22 RPN2_C PF18004.1 CRJ95888.1 - 1.2 9.0 9.8 3.2 7.7 9.8 1.8 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain PPP4R2 PF09184.11 CRJ95888.1 - 1.4 8.5 13.1 1.9 8.0 13.1 1.2 1 0 0 1 1 1 0 PPP4R2 Raftlin PF15250.6 CRJ95888.1 - 1.6 7.4 7.2 2 7.1 7.2 1.2 1 0 0 1 1 1 0 Raftlin Mito_fiss_reg PF05308.11 CRJ95888.1 - 3.1 7.8 14.3 0.073 13.1 4.3 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator NOA36 PF06524.12 CRJ95888.1 - 4 6.7 19.9 6 6.1 19.9 1.2 1 0 0 1 1 1 0 NOA36 protein SAPS PF04499.15 CRJ95888.1 - 4.2 6.0 6.9 5.2 5.7 6.9 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SURF2 PF05477.11 CRJ95888.1 - 5.7 6.6 8.9 8.2 6.0 8.9 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Methyltr_RsmB-F PF01189.17 CRJ95903.1 - 1.7e-75 253.0 0.0 2.9e-75 252.3 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 CRJ95903.1 - 4.8e-07 30.2 0.0 1.4e-06 28.7 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF Met_10 PF02475.16 CRJ95903.1 - 0.0019 18.0 0.0 0.0031 17.3 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.6 CRJ95903.1 - 0.021 15.5 0.0 0.049 14.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Toprim_Crpt PF13342.6 CRJ95903.1 - 0.022 14.7 0.1 0.06 13.3 0.1 1.7 1 0 0 1 1 1 0 C-terminal repeat of topoisomerase DUF2431 PF10354.9 CRJ95903.1 - 0.078 13.2 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) DUF938 PF06080.12 CRJ95903.1 - 0.16 11.7 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Blt1 PF12754.7 CRJ95914.1 - 5.4e-37 127.4 0.7 7.9e-37 126.9 0.7 1.2 1 0 0 1 1 1 1 Blt1 N-terminal domain Blt1_C PF17183.4 CRJ95914.1 - 1.5e-14 53.3 1.6 2.7e-14 52.5 1.6 1.4 1 0 0 1 1 1 1 Get5 carboxyl domain ubiquitin PF00240.23 CRJ95914.1 - 1.5e-05 24.7 0.0 2.4e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Cofilin_ADF PF00241.20 CRJ95921.1 - 5.3e-39 132.8 0.3 6.5e-39 132.5 0.3 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF3991 PF13154.6 CRJ95921.1 - 0.19 12.1 0.4 0.36 11.2 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3991) Cpn60_TCP1 PF00118.24 CRJ95929.1 - 2.6e-46 158.3 1.9 3.2e-46 158.0 1.9 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Rrf2 PF02082.20 CRJ95929.1 - 0.074 13.4 0.3 0.26 11.7 0.1 2.0 2 1 0 2 2 2 0 Transcriptional regulator PatG_C PF18065.1 CRJ95937.1 - 0.06 13.3 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 PatG C-terminal Histone_HNS PF00816.21 CRJ95937.1 - 0.094 13.6 4.4 0.23 12.3 4.1 1.9 1 1 0 1 1 1 0 H-NS histone family FAD_binding_4 PF01565.23 CRJ95946.1 - 5.3e-21 74.8 0.1 1.1e-20 73.7 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 CRJ95946.1 - 0.011 15.8 0.0 0.037 14.1 0.0 1.9 1 0 0 1 1 1 0 Berberine and berberine like Med3 PF11593.8 CRJ95953.1 - 0.66 9.1 5.2 0.74 8.9 5.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Zn_clus PF00172.18 CRJ95964.1 - 0.00047 20.2 10.6 0.0049 17.0 10.6 2.2 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 CRJ95964.1 - 0.0026 16.6 0.1 0.0038 16.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain CTNNB1_binding PF08347.11 CRJ95964.1 - 0.027 14.6 3.8 0.06 13.5 3.8 1.5 1 0 0 1 1 1 0 N-terminal CTNNB1 binding UFD1 PF03152.14 CRJ95979.1 - 1.2e-36 125.8 0.3 1.7e-36 125.3 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 RNA_pol_Rpb5_C PF01191.19 CRJ95979.1 - 0.056 13.3 0.5 0.21 11.5 0.5 1.9 1 1 1 2 2 2 0 RNA polymerase Rpb5, C-terminal domain FliT PF05400.13 CRJ95996.1 - 0.0086 16.9 0.4 0.0086 16.9 0.4 5.1 4 2 0 4 4 4 1 Flagellar protein FliT PLAC9 PF15205.6 CRJ95996.1 - 0.12 12.7 2.4 2 8.9 1.6 3.2 2 1 0 2 2 2 0 Placenta-specific protein 9 ABC_tran_CTD PF16326.5 CRJ95996.1 - 6.9 7.0 27.9 6.5 7.1 0.0 7.0 6 3 2 8 8 8 0 ABC transporter C-terminal domain UFD1 PF03152.14 CRJ96000.1 - 6.2e-69 230.9 0.0 7e-69 230.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 GYF PF02213.16 CRJ96007.1 - 4.7e-12 45.4 2.7 1.1e-11 44.2 2.7 1.7 1 0 0 1 1 1 1 GYF domain Gluconate_2-dh3 PF13618.6 CRJ96007.1 - 0.17 12.2 4.6 0.12 12.6 1.9 2.0 1 1 0 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 TIP49 PF06068.13 CRJ96014.1 - 1e-71 242.0 3.9 1.6e-43 149.3 0.0 2.2 1 1 1 2 2 2 2 TIP49 P-loop domain TIP49_C PF17856.1 CRJ96014.1 - 6.3e-21 74.3 0.5 1.9e-20 72.8 0.4 1.8 2 0 0 2 2 2 1 TIP49 AAA-lid domain RuvB_N PF05496.12 CRJ96014.1 - 4.4e-07 29.8 2.1 0.00098 18.9 0.1 2.4 1 1 1 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CRJ96014.1 - 0.0019 18.6 0.1 0.0048 17.3 0.0 1.7 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 CRJ96014.1 - 0.0072 16.7 2.7 0.52 10.7 0.4 2.7 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CRJ96014.1 - 0.012 15.4 0.3 4.2 7.0 0.0 2.3 1 1 1 2 2 2 0 Sigma-54 interaction domain ATPase PF06745.13 CRJ96014.1 - 0.029 13.7 0.0 0.055 12.8 0.0 1.4 1 0 0 1 1 1 0 KaiC DnaB_C PF03796.15 CRJ96014.1 - 0.031 13.6 0.1 0.072 12.4 0.0 1.5 1 1 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_25 PF13481.6 CRJ96014.1 - 0.037 13.6 0.2 0.077 12.6 0.1 1.6 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 CRJ96014.1 - 0.058 12.5 0.1 0.27 10.3 0.1 1.8 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 PhoH PF02562.16 CRJ96014.1 - 0.07 12.6 0.2 0.11 12.0 0.2 1.5 1 1 0 1 1 1 0 PhoH-like protein AAA_22 PF13401.6 CRJ96014.1 - 0.099 12.9 0.4 3.3 8.0 0.0 2.3 1 1 1 2 2 2 0 AAA domain SpoIIE PF07228.12 CRJ96014.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) AAA_5 PF07728.14 CRJ96014.1 - 0.22 11.5 0.8 28 4.7 0.1 2.7 2 1 0 3 3 3 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 CRJ96014.1 - 0.38 10.1 4.5 3.5 7.0 2.3 2.3 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 CRJ96014.1 - 0.73 10.2 4.4 9.8 6.5 0.6 2.5 2 1 1 3 3 3 0 AAA domain DivIC PF04977.15 CRJ96020.1 - 0.035 13.9 0.4 0.035 13.9 0.4 4.1 5 0 0 5 5 5 0 Septum formation initiator PLAC9 PF15205.6 CRJ96020.1 - 0.22 12.0 2.7 2 8.9 1.6 3.2 2 1 0 2 2 2 0 Placenta-specific protein 9 FliT PF05400.13 CRJ96020.1 - 0.96 10.3 18.4 0.67 10.8 0.1 5.0 4 1 0 4 4 4 0 Flagellar protein FliT ZapB PF06005.12 CRJ96020.1 - 1.1 9.8 16.3 0.36 11.3 0.3 5.2 5 1 0 5 5 5 0 Cell division protein ZapB ABC_tran_CTD PF16326.5 CRJ96020.1 - 2.9 8.2 21.9 6.4 7.1 0.0 6.5 5 2 2 8 8 8 0 ABC transporter C-terminal domain Sin3_corepress PF08295.12 CRJ96020.1 - 3.3 7.9 6.4 7.7 6.7 0.1 3.8 4 0 0 4 4 4 0 Sin3 family co-repressor bZIP_1 PF00170.21 CRJ96020.1 - 6.6 6.9 8.5 4.6 7.4 0.1 4.3 4 0 0 4 4 4 0 bZIP transcription factor Gp_dh_C PF02800.20 CRJ96038.1 - 1.6e-71 239.0 0.5 2.4e-71 238.4 0.5 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 CRJ96038.1 - 1.4e-39 134.5 0.1 3.9e-39 133.1 0.1 1.7 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 CRJ96038.1 - 0.0029 17.7 0.4 0.011 15.8 0.0 2.2 2 1 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.19 CRJ96038.1 - 0.022 14.1 0.1 0.057 12.8 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NADHdh_A3 PF14987.6 CRJ96057.1 - 0.054 13.8 0.1 0.11 12.8 0.1 1.5 1 0 0 1 1 1 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 HTH_20 PF12840.7 CRJ96057.1 - 0.17 12.0 0.1 0.32 11.1 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain MAGE_N PF12440.8 CRJ96057.1 - 0.73 10.6 3.6 1.2 9.8 3.6 1.3 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal GET2 PF08690.10 CRJ96061.1 - 3.1e-15 56.7 0.0 5.4e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 GET complex subunit GET2 OapA_N PF08525.11 CRJ96061.1 - 0.00042 20.2 0.0 2.5 8.1 0.0 3.4 2 0 0 2 2 2 2 Opacity-associated protein A N-terminal motif Fer4_19 PF06902.11 CRJ96061.1 - 0.0052 16.8 0.0 5.5 7.1 0.0 2.4 2 0 0 2 2 2 2 Divergent 4Fe-4S mono-cluster HLH PF00010.26 CRJ96071.1 - 4.2e-07 29.8 0.0 8.3e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HLH PF00010.26 CRJ96081.1 - 4.1e-07 29.9 0.0 8.3e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain GET2 PF08690.10 CRJ96088.1 - 4.2e-66 223.7 0.0 2.5e-44 152.2 0.0 2.9 2 0 0 2 2 2 2 GET complex subunit GET2 Sec16_C PF12931.7 CRJ96088.1 - 3.2e-15 56.6 0.1 4.3e-07 29.9 0.1 3.2 2 1 0 2 2 2 2 Sec23-binding domain of Sec16 Prp18 PF02840.15 CRJ96088.1 - 6.8e-07 29.4 0.6 0.027 14.5 0.1 2.5 2 0 0 2 2 2 2 Prp18 domain WD40 PF00400.32 CRJ96088.1 - 4.3e-06 27.4 6.7 0.024 15.5 0.1 6.2 8 0 0 8 8 8 1 WD domain, G-beta repeat Sec16 PF12932.7 CRJ96088.1 - 7.4e-06 26.6 0.1 0.26 11.9 0.0 3.4 2 0 0 2 2 2 2 Vesicle coat trafficking protein Sec16 mid-region B12D PF06522.11 CRJ96088.1 - 0.00045 20.0 0.0 0.0012 18.6 0.0 1.7 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit SRA1 PF07304.11 CRJ96088.1 - 0.00079 19.2 2.7 0.0016 18.2 1.3 5.5 5 1 1 6 6 6 2 Steroid receptor RNA activator (SRA1) DUF4148 PF13663.6 CRJ96088.1 - 0.0064 16.7 0.1 8.4 6.7 0.0 2.9 2 0 0 2 2 2 2 Domain of unknown function (DUF4148) Phytochelatin_C PF09328.10 CRJ96088.1 - 0.024 13.9 0.2 3.6 6.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1984) COX6B PF02297.17 CRJ96099.1 - 3.1e-18 65.8 5.0 3.5e-18 65.6 5.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CX9C PF16860.5 CRJ96099.1 - 0.043 13.8 2.7 0.067 13.2 2.7 1.2 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, APOBEC_C PF05240.14 CRJ96099.1 - 0.084 12.8 2.5 0.076 13.0 1.6 1.5 1 1 0 1 1 1 0 APOBEC-like C-terminal domain CHCH PF06747.13 CRJ96099.1 - 0.092 12.9 0.8 0.24 11.6 0.8 1.7 1 1 0 1 1 1 0 CHCH domain ketoacyl-synt PF00109.26 CRJ96099.1 - 0.11 12.1 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain Sde2_N_Ubi PF13019.6 CRJ96105.1 - 5.3e-70 234.5 0.3 9.1e-70 233.7 0.3 1.4 1 0 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain Peripla_BP_6 PF13458.6 CRJ96105.1 - 0.095 12.3 0.1 0.15 11.7 0.1 1.2 1 0 0 1 1 1 0 Periplasmic binding protein S10_plectin PF03501.15 CRJ96112.1 - 6.7e-42 141.5 0.1 8.1e-42 141.2 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain ADH_N PF08240.12 CRJ96120.1 - 2.5e-34 117.4 0.6 5.1e-34 116.4 0.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CRJ96120.1 - 1.9e-15 57.0 0.0 3.1e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 CRJ96120.1 - 1.7e-10 40.8 0.0 2.6e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 CRJ96120.1 - 1.9e-09 38.7 0.0 3.5e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.19 CRJ96120.1 - 0.0033 16.7 0.2 0.0053 16.1 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain HTH_psq PF05225.16 CRJ96120.1 - 0.081 12.7 0.1 2.1 8.2 0.1 2.3 2 0 0 2 2 2 0 helix-turn-helix, Psq domain Staph_opine_DH PF10100.9 CRJ96120.1 - 0.13 10.9 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 Staphylopine dehydrogenase NCA2 PF08637.10 CRJ96132.1 - 3e-110 367.9 0.0 7.8e-110 366.6 0.0 1.7 2 0 0 2 2 2 1 ATP synthase regulation protein NCA2 FA_hydroxylase PF04116.13 CRJ96140.1 - 1.3e-24 87.1 16.4 1.3e-24 87.1 16.4 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily bZIP_1 PF00170.21 CRJ96140.1 - 6.8e-08 32.5 6.9 6.8e-08 32.5 6.9 1.8 2 0 0 2 2 2 1 bZIP transcription factor SUIM_assoc PF16619.5 CRJ96140.1 - 1.1e-05 25.3 11.0 0.00039 20.4 6.2 3.6 2 2 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 DUF3158 PF11358.8 CRJ96140.1 - 0.022 14.5 0.1 0.039 13.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3158) Pterin_4a PF01329.19 CRJ96147.1 - 1.6e-23 82.7 0.0 2.4e-23 82.1 0.0 1.2 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase PCSK9_C3 PF18463.1 CRJ96147.1 - 0.087 13.1 2.7 0.27 11.5 2.7 1.9 1 1 0 1 1 1 0 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain Actin PF00022.19 CRJ96157.1 - 3.5e-53 180.7 0.0 5.7e-32 110.8 0.0 2.2 2 0 0 2 2 2 2 Actin Got1 PF04178.12 CRJ96168.1 - 7.5e-15 55.3 11.9 9.4e-15 55.0 11.9 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family Profilin PF00235.19 CRJ96175.1 - 4.1e-46 156.4 0.7 4.5e-46 156.2 0.7 1.0 1 0 0 1 1 1 1 Profilin K_trans PF02705.16 CRJ96184.1 - 3.4e-182 606.7 14.1 4e-182 606.4 14.1 1.0 1 0 0 1 1 1 1 K+ potassium transporter TAT_signal PF10518.9 CRJ96184.1 - 0.073 12.9 0.1 0.2 11.6 0.1 1.8 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence IBR PF01485.21 CRJ96189.1 - 0.0094 16.2 0.1 0.016 15.4 0.1 1.4 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain RSS_P20 PF11757.8 CRJ96189.1 - 0.46 11.0 2.1 0.41 11.1 0.5 1.7 2 0 0 2 2 2 0 Suppressor of RNA silencing P21-like N-terminal domain GMP_synt_C PF00958.22 CRJ96197.1 - 1.5e-35 121.1 0.0 3.1e-35 120.1 0.0 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 CRJ96197.1 - 4.4e-33 114.7 0.0 7.2e-33 114.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 CRJ96197.1 - 1.4e-08 34.2 0.0 1.4e-05 24.3 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 CRJ96197.1 - 0.00024 20.9 0.0 0.00051 19.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.16 CRJ96197.1 - 0.0013 17.6 0.0 0.0026 16.6 0.0 1.4 2 0 0 2 2 2 1 tRNA methyl transferase QueC PF06508.13 CRJ96197.1 - 0.015 14.8 0.0 0.076 12.5 0.0 1.9 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC PAPS_reduct PF01507.19 CRJ96197.1 - 0.032 14.3 0.0 0.056 13.5 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Arginosuc_synth PF00764.19 CRJ96197.1 - 0.088 12.1 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Arginosuccinate synthase ATP_bind_3 PF01171.20 CRJ96197.1 - 0.2 11.4 0.0 0.44 10.3 0.0 1.6 1 0 0 1 1 1 0 PP-loop family adh_short PF00106.25 CRJ96215.1 - 2e-06 27.4 0.1 2.6e-06 27.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRJ96215.1 - 0.0024 17.5 0.1 0.0036 16.9 0.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRJ96221.1 - 6.4e-24 84.5 0.1 9.7e-22 77.4 0.1 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRJ96221.1 - 8.7e-11 41.8 0.0 9.2e-09 35.2 0.0 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRJ96221.1 - 1.5e-06 28.2 0.0 2e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CRJ96221.1 - 0.01 15.3 0.0 0.017 14.6 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 CRJ96221.1 - 0.019 14.1 0.0 0.029 13.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Synaptobrevin PF00957.21 CRJ96230.1 - 3.7e-14 52.3 0.5 6.5e-14 51.5 0.5 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 CRJ96230.1 - 1.5e-07 31.3 0.0 3.4e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Regulated-SNARE-like domain FAM131 PF15010.6 CRJ96230.1 - 0.0057 16.6 0.7 0.0076 16.2 0.7 1.4 1 0 0 1 1 1 1 Putative cell signalling AcetDehyd-dimer PF09290.11 CRJ96230.1 - 0.14 12.3 0.2 0.33 11.1 0.1 1.6 2 0 0 2 2 2 0 Prokaryotic acetaldehyde dehydrogenase, dimerisation Sec63 PF02889.16 CRJ96243.1 - 1.6e-233 771.4 0.0 1.1e-52 178.7 0.0 7.2 5 1 2 7 7 7 7 Sec63 Brl domain DEAD PF00270.29 CRJ96243.1 - 5.9e-79 263.9 0.0 3.8e-21 75.6 0.0 5.9 5 0 0 5 5 5 4 DEAD/DEAH box helicase ResIII PF04851.15 CRJ96243.1 - 4.8e-35 121.1 0.0 1.2e-10 41.7 0.0 4.4 4 0 0 4 4 4 4 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CRJ96243.1 - 1.4e-21 76.9 2.3 3.3e-06 27.4 0.0 7.8 7 1 0 7 7 6 3 Helicase conserved C-terminal domain AAA_30 PF13604.6 CRJ96243.1 - 3.3e-10 40.0 0.8 0.31 10.7 0.0 4.5 4 0 0 4 4 4 3 AAA domain AAA_22 PF13401.6 CRJ96243.1 - 2.8e-09 37.4 0.1 0.15 12.4 0.0 5.3 4 2 0 4 4 4 1 AAA domain AAA_19 PF13245.6 CRJ96243.1 - 0.00017 21.9 0.9 9 6.6 0.1 4.5 4 0 0 4 4 4 0 AAA domain T2SSE PF00437.20 CRJ96243.1 - 0.0022 17.1 0.0 2.4 7.1 0.0 2.6 2 0 0 2 2 2 2 Type II/IV secretion system protein Helicase_PWI PF18149.1 CRJ96243.1 - 0.0029 17.7 0.0 0.0075 16.4 0.0 1.7 1 0 0 1 1 1 1 N-terminal helicase PWI domain PIF1 PF05970.14 CRJ96243.1 - 0.016 14.4 0.8 5.8 6.0 0.1 2.6 2 0 0 2 2 2 0 PIF1-like helicase DUF1574 PF07611.11 CRJ96243.1 - 0.025 13.9 0.3 6.4 6.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1574) Glyco_trans_4_5 PF16994.5 CRJ96243.1 - 0.026 14.2 0.2 26 4.4 0.0 3.9 5 0 0 5 5 5 0 Glycosyl-transferase family 4 DUF4688 PF15752.5 CRJ96243.1 - 0.026 13.8 0.0 22 4.1 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4688) AAA_5 PF07728.14 CRJ96243.1 - 0.036 14.1 1.5 12 5.9 0.1 3.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF1077 PF06417.12 CRJ96243.1 - 0.043 13.8 0.3 15 5.7 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1077) PhoH PF02562.16 CRJ96243.1 - 0.047 13.1 0.0 11 5.4 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein DUF3365 PF11845.8 CRJ96243.1 - 0.061 13.6 0.2 23 5.3 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3365) DUF505 PF04458.12 CRJ96243.1 - 0.099 11.0 0.0 12 4.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF505) DUF1815 PF08844.10 CRJ96243.1 - 0.14 12.2 0.0 39 4.3 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1815) Zeta_toxin PF06414.12 CRJ96243.1 - 0.16 11.3 0.0 25 4.1 0.0 2.7 2 0 0 2 2 2 0 Zeta toxin TniB PF05621.11 CRJ96243.1 - 2.1 7.7 7.8 34 3.8 0.1 4.7 6 0 0 6 6 6 0 Bacterial TniB protein Roc PF08477.13 CRJ96256.1 - 3.6e-16 59.5 0.1 4.1e-16 59.3 0.1 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CRJ96256.1 - 1e-13 51.2 0.2 1.2e-13 51.0 0.2 1.0 1 0 0 1 1 1 1 Ras family Arf PF00025.21 CRJ96256.1 - 0.00043 19.8 0.0 0.00045 19.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CRJ96256.1 - 0.0012 18.9 0.1 0.0013 18.8 0.1 1.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 CRJ96256.1 - 0.0044 17.4 0.1 0.0044 17.4 0.1 1.1 1 0 0 1 1 1 1 AAA ATPase domain Dynamin_N PF00350.23 CRJ96256.1 - 0.0063 16.6 0.1 0.0063 16.6 0.1 1.1 1 0 0 1 1 1 1 Dynamin family SRPRB PF09439.10 CRJ96256.1 - 0.0084 15.6 0.1 0.0087 15.5 0.1 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 CRJ96256.1 - 0.0092 15.7 0.0 0.01 15.6 0.0 1.2 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CRJ96256.1 - 0.01 15.8 0.0 0.011 15.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 CRJ96256.1 - 0.024 14.5 0.1 0.024 14.5 0.1 1.1 1 0 0 1 1 1 0 RsgA GTPase NACHT PF05729.12 CRJ96256.1 - 0.031 14.2 0.1 0.032 14.2 0.1 1.1 1 0 0 1 1 1 0 NACHT domain Septin PF00735.18 CRJ96256.1 - 0.031 13.6 0.0 0.034 13.4 0.0 1.1 1 0 0 1 1 1 0 Septin AAA_28 PF13521.6 CRJ96256.1 - 0.032 14.5 0.1 0.032 14.5 0.1 1.1 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 CRJ96256.1 - 0.033 14.6 0.0 0.033 14.6 0.0 1.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 CRJ96256.1 - 0.04 13.4 0.2 0.044 13.3 0.2 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 CRJ96256.1 - 0.044 13.2 0.0 0.046 13.1 0.0 1.1 1 0 0 1 1 1 0 Bacterial TniB protein DLIC PF05783.11 CRJ96256.1 - 0.062 12.1 0.0 0.07 12.0 0.0 1.0 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_14 PF13173.6 CRJ96256.1 - 0.077 13.0 0.0 0.077 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CRJ96256.1 - 0.1 13.0 0.0 0.11 12.9 0.0 1.2 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.17 CRJ96256.1 - 0.15 12.1 0.1 0.16 12.0 0.1 1.1 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 CRJ96256.1 - 0.16 12.2 0.0 0.17 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain MFS_1 PF07690.16 CRJ96273.1 - 2.6e-43 148.3 37.9 2.6e-43 148.3 37.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CRJ96273.1 - 1.2e-13 50.7 9.5 1.2e-13 50.7 9.5 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter Hydrophobin_2 PF06766.11 CRJ96283.1 - 1.1e-22 79.7 6.8 2.3e-22 78.7 6.8 1.5 1 1 0 1 1 1 1 Fungal hydrophobin Fungal_trans PF04082.18 CRJ96292.1 - 4.9e-10 38.9 1.2 2.7e-08 33.2 0.1 2.6 2 1 1 3 3 3 2 Fungal specific transcription factor domain DJ-1_PfpI PF01965.24 CRJ96292.1 - 6.8e-05 22.7 0.0 0.0003 20.6 0.0 2.0 1 1 0 1 1 1 1 DJ-1/PfpI family RAG1_imp_bd PF12560.8 CRJ96292.1 - 0.2 11.2 0.0 0.29 10.6 0.0 1.2 1 0 0 1 1 1 0 RAG1 importin binding MFS_1 PF07690.16 CRJ96311.1 - 3.3e-37 128.2 37.1 3.3e-37 128.2 37.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CRJ96311.1 - 5.8e-11 41.9 5.7 5.8e-11 41.9 5.7 1.6 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 CRJ96311.1 - 1e-07 31.6 4.2 1e-07 31.6 4.2 2.3 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 CRJ96311.1 - 0.0027 16.2 0.3 0.0042 15.6 0.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FMN_dh PF01070.18 CRJ96322.1 - 1e-122 409.5 0.6 1.2e-122 409.2 0.6 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 CRJ96322.1 - 4.6e-22 77.9 0.1 9.1e-22 77.0 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 CRJ96322.1 - 7e-09 35.3 0.1 1.1e-08 34.6 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 CRJ96322.1 - 0.00016 20.8 0.6 0.00042 19.4 0.1 1.8 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 CRJ96322.1 - 0.0093 15.5 1.3 0.49 9.8 0.3 2.3 1 1 1 2 2 2 2 Histidine biosynthesis protein NMO PF03060.15 CRJ96322.1 - 0.012 15.0 0.7 0.012 15.0 0.7 1.6 2 0 0 2 2 2 0 Nitronate monooxygenase G3P_antiterm PF04309.12 CRJ96322.1 - 0.034 13.6 0.0 0.96 8.8 0.0 2.3 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator DUF561 PF04481.12 CRJ96322.1 - 0.051 12.7 0.0 1.9 7.6 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF561) T6SS_VasJ PF16989.5 CRJ96322.1 - 0.06 12.8 0.1 0.13 11.7 0.0 1.6 2 0 0 2 2 2 0 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ ThiG PF05690.14 CRJ96322.1 - 0.07 12.4 0.5 5.6 6.2 0.0 2.3 1 1 0 2 2 2 0 Thiazole biosynthesis protein ThiG WSC PF01822.19 CRJ96344.1 - 1.4e-12 47.6 4.3 1.4e-12 47.6 4.3 3.1 3 0 0 3 3 3 2 WSC domain Glyco_hydro_16 PF00722.21 CRJ96344.1 - 4.1e-06 26.4 2.1 1e-05 25.1 0.0 2.5 3 0 0 3 3 3 1 Glycosyl hydrolases family 16 Pex2_Pex12 PF04757.14 CRJ96353.1 - 1.6e-50 171.8 3.7 2e-50 171.5 3.7 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.6 CRJ96353.1 - 0.0031 17.3 2.1 0.0056 16.5 2.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CRJ96353.1 - 0.0043 17.2 1.8 0.0073 16.4 1.8 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 CRJ96353.1 - 0.012 15.6 1.2 0.021 14.9 1.2 1.4 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CRJ96353.1 - 0.014 15.3 1.3 0.021 14.7 1.3 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CRJ96353.1 - 0.062 13.2 1.2 0.1 12.5 1.2 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CRJ96353.1 - 0.085 13.2 2.5 0.15 12.4 2.5 1.3 1 0 0 1 1 1 0 Ring finger domain 4HBT PF03061.22 CRJ96363.1 - 3e-12 46.7 0.1 4e-12 46.3 0.1 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 CRJ96363.1 - 0.00062 20.1 0.1 0.001 19.4 0.1 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily Fungal_trans PF04082.18 CRJ96370.1 - 1.7e-67 227.3 0.1 2.4e-67 226.8 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 CRJ96370.1 - 2.6e-05 24.4 10.0 0.00056 20.2 0.7 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type F-box-like PF12937.7 CRJ96370.1 - 4.1e-05 23.4 0.2 8e-05 22.5 0.2 1.5 1 0 0 1 1 1 1 F-box-like zf-C2H2_4 PF13894.6 CRJ96370.1 - 0.0076 17.0 7.8 0.087 13.7 0.5 3.3 2 0 0 2 2 2 1 C2H2-type zinc finger F-box PF00646.33 CRJ96370.1 - 0.041 13.8 0.0 0.077 12.9 0.0 1.5 1 0 0 1 1 1 0 F-box domain DnaJ_C PF01556.18 CRJ96391.1 - 2e-36 125.3 0.0 3e-36 124.7 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CRJ96391.1 - 1.2e-24 86.2 0.7 2.2e-24 85.3 0.7 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CRJ96391.1 - 1.6e-08 34.8 23.5 3.8e-08 33.6 23.5 1.7 1 0 0 1 1 1 1 DnaJ central domain SAP30_Sin3_bdg PF13867.6 CRJ96391.1 - 4e-06 27.1 1.2 9.1e-06 25.9 0.0 2.2 3 0 0 3 3 3 1 Sin3 binding region of histone deacetylase complex subunit SAP30 Gene66 PF02053.15 CRJ96391.1 - 0.18 11.4 0.2 22 4.6 0.0 2.2 2 0 0 2 2 2 0 Gene 66 (IR5) protein Cytochrome_C7 PF14522.6 CRJ96391.1 - 7.3 6.7 9.3 0.67 10.0 2.3 2.5 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c BRO1 PF03097.18 CRJ96401.1 - 5.8e-134 446.8 0.9 5.8e-134 446.8 0.9 1.8 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 CRJ96401.1 - 1.5e-57 195.2 19.2 3.6e-57 193.9 19.2 1.6 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV TPR_21 PF09976.9 CRJ96401.1 - 0.016 14.9 3.7 0.07 12.8 3.7 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain DUF416 PF04222.12 CRJ96401.1 - 1.1 8.6 11.4 0.13 11.6 0.4 3.9 2 2 2 4 4 4 0 Protein of unknown function (DUF416) Sugar_tr PF00083.24 CRJ96412.1 - 1.1e-55 189.4 13.6 1.8e-52 178.7 8.6 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter Sulfatase PF00884.23 CRJ96412.1 - 2.6e-39 135.5 0.0 4e-39 134.8 0.0 1.2 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 CRJ96412.1 - 2.3e-14 53.5 2.9 2.3e-14 53.5 2.9 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF4976) Phosphodiest PF01663.22 CRJ96412.1 - 0.0065 16.1 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Fungal_trans PF04082.18 CRJ96412.1 - 0.019 14.0 0.0 0.041 12.9 0.0 1.6 1 0 0 1 1 1 0 Fungal specific transcription factor domain DUF229 PF02995.17 CRJ96412.1 - 0.051 12.2 0.1 0.08 11.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Abhydrolase_6 PF12697.7 CRJ96424.1 - 3.7e-05 24.4 0.1 7.4e-05 23.5 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 CRJ96424.1 - 0.00052 19.6 0.5 0.0021 17.6 0.4 1.7 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 CRJ96424.1 - 0.002 17.4 0.0 0.004 16.5 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Cutinase PF01083.22 CRJ96424.1 - 0.025 14.5 0.0 0.051 13.5 0.0 1.4 1 0 0 1 1 1 0 Cutinase Abhydrolase_1 PF00561.20 CRJ96424.1 - 0.037 13.7 0.1 0.084 12.5 0.1 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.13 CRJ96424.1 - 0.04 13.6 0.2 0.1 12.3 0.2 1.6 1 1 0 1 1 1 0 PGAP1-like protein DUF3089 PF11288.8 CRJ96424.1 - 0.14 11.7 0.1 1.6 8.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3089) FA_desaturase PF00487.24 CRJ96449.1 - 3.4e-17 63.1 13.3 3.4e-17 63.1 13.3 2.0 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 CRJ96449.1 - 5.8e-17 61.6 0.0 1.2e-16 60.6 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain AZUL PF16558.5 CRJ96952.1 - 2.9e-14 53.0 1.7 4.3e-14 52.5 1.7 1.3 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A HECT PF00632.25 CRJ96957.1 - 1.4e-77 261.2 0.0 3.9e-77 259.8 0.0 1.7 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) CDC45 PF02724.14 CRJ96957.1 - 0.019 13.3 8.4 0.035 12.4 8.4 1.4 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 CRJ96957.1 - 0.65 8.1 16.8 1.1 7.4 16.8 1.2 1 0 0 1 1 1 0 Nop14-like family SpoIIIAH PF12685.7 CRJ96957.1 - 4.3 7.1 12.3 9 6.1 12.3 1.5 1 0 0 1 1 1 0 SpoIIIAH-like protein SAPS PF04499.15 CRJ96957.1 - 8.7 5.0 7.0 16 4.1 7.0 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein HECT PF00632.25 CRJ96966.1 - 1.4e-55 189.0 0.0 2.2e-55 188.3 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) AZUL PF16558.5 CRJ96966.1 - 7.3e-20 71.0 4.0 7.3e-20 71.0 4.0 2.2 2 0 0 2 2 2 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A Lipase_GDSL PF00657.22 CRJ96966.1 - 0.0025 17.8 0.0 0.0046 16.9 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase SPR1 PF15356.6 CRJ96966.1 - 0.69 10.4 16.3 0.17 12.4 11.8 2.3 2 0 0 2 2 2 0 Psoriasis susceptibility locus 2 Abhydrolase_6 PF12697.7 CRJ96966.1 - 4.9 7.7 6.6 4.8 7.7 0.0 3.6 3 2 1 4 4 4 0 Alpha/beta hydrolase family zf-C2H2_2 PF12756.7 CRJ96974.1 - 4.9e-36 123.1 31.0 2.2e-27 95.3 4.1 5.1 6 0 0 6 6 6 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 CRJ96974.1 - 1e-07 32.0 4.2 1e-07 32.0 4.2 4.5 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CRJ96974.1 - 1.5e-05 25.2 3.6 1.5e-05 25.2 3.6 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type Mso1_Sec1_bdg PF14475.6 CRJ96974.1 - 0.056 13.0 1.2 20 4.9 0.1 3.5 2 0 0 2 2 2 0 Sec1-binding region of Mso1 zf-C2H2_4 PF13894.6 CRJ96974.1 - 0.12 13.2 21.4 0.7 10.9 0.2 5.7 6 0 0 6 6 6 0 C2H2-type zinc finger SnoaL_2 PF12680.7 CRJ96974.1 - 0.16 12.6 7.4 5.7 7.7 0.3 3.4 4 0 0 4 4 4 0 SnoaL-like domain A_deaminase PF00962.22 CRJ96979.1 - 1.1e-48 166.3 0.0 7e-23 81.5 0.0 3.1 2 1 0 2 2 2 2 Adenosine/AMP deaminase A_deaminase_N PF08451.11 CRJ96979.1 - 4.3e-05 23.7 4.4 0.031 14.6 0.2 3.1 3 0 0 3 3 3 2 Adenosine/AMP deaminase N-terminal DUF2158 PF09926.9 CRJ96979.1 - 0.016 14.9 0.0 10 5.9 0.0 2.7 2 0 0 2 2 2 0 Uncharacterized small protein (DUF2158) NfrA_C PF13283.6 CRJ96979.1 - 0.14 11.6 0.3 12 5.3 0.1 2.5 2 0 0 2 2 2 0 Bacteriophage N adsorption protein A C-term ANAPC_CDC26 PF10471.9 CRJ96979.1 - 2.1 9.3 4.4 45 5.0 0.3 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 HECT PF00632.25 CRJ96986.1 - 1.7e-64 218.2 0.0 2.3e-64 217.8 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Abhydrolase_6 PF12697.7 CRJ96986.1 - 0.55 10.8 3.5 0.51 10.9 0.1 2.4 2 1 0 2 2 2 0 Alpha/beta hydrolase family SPR1 PF15356.6 CRJ96994.1 - 0.93 10.0 16.2 1.3 9.5 12.2 2.6 2 0 0 2 2 2 0 Psoriasis susceptibility locus 2 HECT PF00632.25 CRJ97002.1 - 3.2e-77 260.0 0.0 7.2e-77 258.9 0.0 1.6 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Arm PF00514.23 CRJ97002.1 - 0.0005 20.0 1.5 1.3 9.2 0.1 5.0 5 1 0 5 5 5 1 Armadillo/beta-catenin-like repeat HEAT PF02985.22 CRJ97002.1 - 0.041 14.1 0.0 0.52 10.7 0.0 3.0 2 0 0 2 2 2 0 HEAT repeat HEAT_EZ PF13513.6 CRJ97002.1 - 0.092 13.3 0.0 0.66 10.5 0.0 2.6 1 0 0 1 1 1 0 HEAT-like repeat CLASP_N PF12348.8 CRJ97002.1 - 0.11 12.0 0.7 0.92 9.0 0.0 2.5 3 0 0 3 3 3 0 CLASP N terminal E1_dh PF00676.20 CRJ97011.1 - 4.2e-83 278.7 0.0 5.1e-83 278.5 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 CRJ97011.1 - 0.02 14.7 0.0 0.22 11.3 0.0 2.2 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Ubie_methyltran PF01209.18 CRJ97019.1 - 5.7e-48 163.3 0.0 8.2e-48 162.8 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 CRJ97019.1 - 4.2e-14 53.0 0.0 8e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CRJ97019.1 - 1.9e-12 47.7 0.0 4.1e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRJ97019.1 - 2.2e-11 44.3 0.0 4.5e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRJ97019.1 - 4e-08 33.2 0.0 6.3e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CRJ97019.1 - 1.6e-05 24.8 0.0 2.4e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 CRJ97019.1 - 0.056 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Hypothetical methyltransferase GP40 PF11025.8 CRJ97028.1 - 5 6.9 12.3 6.9 6.4 12.3 1.1 1 0 0 1 1 1 0 Glycoprotein GP40 of Cryptosporidium CDC27 PF09507.10 CRJ97028.1 - 8.2 5.7 19.0 11 5.2 19.0 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 E1_dh PF00676.20 CRJ97037.1 - 3.1e-71 239.8 0.0 4.2e-71 239.3 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 CRJ97037.1 - 0.033 14.0 0.0 0.32 10.8 0.0 2.2 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain SGS PF05002.15 CRJ97037.1 - 0.11 12.6 1.9 7.3 6.8 0.1 2.9 3 0 0 3 3 3 0 SGS domain Ubie_methyltran PF01209.18 CRJ97042.1 - 1.4e-76 256.9 0.0 1.7e-76 256.6 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 CRJ97042.1 - 3.2e-15 56.6 0.0 3.5e-14 53.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CRJ97042.1 - 1.2e-13 51.5 0.0 1.2e-12 48.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRJ97042.1 - 2.8e-11 44.0 0.0 5.3e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRJ97042.1 - 2.5e-08 33.9 0.0 3.4e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CRJ97042.1 - 6.3e-07 29.4 0.0 9.5e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 CRJ97042.1 - 0.016 15.0 0.0 0.13 12.1 0.0 2.1 2 0 0 2 2 2 0 Hypothetical methyltransferase Zds_C PF08632.10 CRJ97054.1 - 8.4e-28 95.9 1.4 8.4e-28 95.9 1.4 1.7 2 0 0 2 2 2 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term TFIIA PF03153.13 CRJ97054.1 - 0.086 12.8 67.4 0.84 9.6 10.9 3.5 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit Zds_C PF08632.10 CRJ97063.1 - 4.1e-20 71.3 1.1 8.1e-20 70.3 1.1 1.5 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term adh_short_C2 PF13561.6 CRJ97070.1 - 4.2e-41 141.0 5.0 5.7e-41 140.6 5.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRJ97070.1 - 6.9e-32 110.5 0.8 8.8e-32 110.1 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CRJ97070.1 - 2.1e-06 27.8 0.9 3e-06 27.3 0.9 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CRJ97070.1 - 0.065 12.7 0.2 0.11 12.0 0.2 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Complex1_30kDa PF00329.19 CRJ97087.1 - 1.3e-44 151.7 0.0 1.9e-44 151.2 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit PIP49_N PF14875.6 CRJ97087.1 - 0.2 11.5 0.0 0.29 11.0 0.0 1.2 1 0 0 1 1 1 0 N-term cysteine-rich ER, FAM69 zf-RING_4 PF14570.6 CRJ97094.1 - 4.1e-20 71.3 11.3 7.3e-20 70.5 11.3 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.22 CRJ97094.1 - 8.7e-10 38.3 0.0 2.5e-09 36.8 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.6 CRJ97094.1 - 5e-07 29.5 7.4 8.5e-07 28.7 7.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CRJ97094.1 - 0.00033 20.9 9.8 0.00063 20.0 9.8 1.5 1 0 0 1 1 1 1 Ring finger domain SET_assoc PF11767.8 CRJ97094.1 - 0.0009 18.8 0.1 0.0019 17.8 0.1 1.5 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated Prok-RING_4 PF14447.6 CRJ97094.1 - 0.0025 17.6 8.8 0.13 12.1 8.9 2.4 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Rtf2 PF04641.12 CRJ97094.1 - 0.0055 16.1 3.2 0.0055 16.1 3.2 3.6 3 1 1 4 4 2 1 Rtf2 RING-finger Nup35_RRM_2 PF14605.6 CRJ97094.1 - 0.035 14.1 0.0 0.064 13.3 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Baculo_IE-1 PF05290.11 CRJ97094.1 - 0.078 12.9 4.8 0.15 12.0 4.8 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-C3HC4 PF00097.25 CRJ97094.1 - 0.18 11.7 10.0 0.39 10.6 10.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 CRJ97094.1 - 0.23 11.6 3.8 0.58 10.3 3.8 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_5 PF14634.6 CRJ97094.1 - 0.33 10.9 9.6 0.64 10.0 9.6 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CRJ97094.1 - 0.46 10.4 9.6 0.88 9.5 9.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ion_trans_2 PF07885.16 CRJ97104.1 - 1.2e-33 114.9 17.9 5.3e-18 64.8 3.3 2.3 2 0 0 2 2 2 2 Ion channel Ion_trans PF00520.31 CRJ97104.1 - 0.0007 18.9 7.1 0.12 11.6 1.9 2.5 2 1 0 2 2 2 2 Ion transport protein Lig_chan PF00060.26 CRJ97104.1 - 0.04 13.7 6.6 0.3 10.9 1.6 3.2 3 0 0 3 3 3 0 Ligand-gated ion channel UME PF08064.13 CRJ97104.1 - 0.085 12.8 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 UME (NUC010) domain Exo_endo_phos PF03372.23 CRJ97123.1 - 7.4e-07 28.9 0.0 1.5e-06 27.9 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ion_trans_2 PF07885.16 CRJ97129.1 - 4.4e-31 106.7 17.4 2.6e-18 65.7 2.9 3.0 4 0 0 4 4 4 2 Ion channel Lig_chan PF00060.26 CRJ97129.1 - 0.0043 16.9 4.3 0.82 9.5 2.3 3.6 2 1 1 3 3 3 2 Ligand-gated ion channel Ion_trans PF00520.31 CRJ97129.1 - 0.058 12.6 13.7 0.12 11.5 0.2 2.8 2 1 0 2 2 2 0 Ion transport protein Abhydrolase_3 PF07859.13 CRJ97136.1 - 0.003 17.4 3.8 0.0035 17.2 0.0 2.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold PRP9_N PF16958.5 CRJ97136.1 - 0.071 13.1 0.4 0.11 12.6 0.4 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor PRP9 N-terminus PTPA PF03095.15 CRJ97145.1 - 2.6e-109 365.3 0.0 3.1e-109 365.1 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Sulfatase PF00884.23 CRJ97150.1 - 4e-13 49.4 0.9 2.9e-12 46.6 1.0 2.0 2 0 0 2 2 2 1 Sulfatase Phosphodiest PF01663.22 CRJ97150.1 - 2.3e-05 24.2 0.0 4.1e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 CRJ97150.1 - 0.13 10.8 0.3 0.21 10.1 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) SprT-like PF10263.9 CRJ97156.1 - 0.22 11.4 1.4 0.65 9.9 1.4 1.8 1 1 0 1 1 1 0 SprT-like family NAAA-beta PF15508.6 CRJ97164.1 - 6.5e-15 55.2 0.1 2.2e-14 53.5 0.1 1.8 2 0 0 2 2 2 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Oxidored_FMN PF00724.20 CRJ97184.1 - 1.1e-79 268.3 0.0 1.4e-79 267.8 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF1848 PF08902.11 CRJ97184.1 - 0.029 14.1 0.0 0.045 13.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) AP_endonuc_2 PF01261.24 CRJ97184.1 - 0.055 12.9 0.0 0.14 11.6 0.0 1.6 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel Cutinase PF01083.22 CRJ97192.1 - 9.2e-36 123.5 4.4 1.3e-35 123.0 4.4 1.2 1 0 0 1 1 1 1 Cutinase Abhydrolase_1 PF00561.20 CRJ97192.1 - 8.1e-12 45.3 0.3 6.1e-06 26.1 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CRJ97192.1 - 6.5e-10 40.0 2.1 3.9e-06 27.6 0.3 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CRJ97192.1 - 6.9e-06 25.5 0.2 0.0081 15.5 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 PE-PPE PF08237.11 CRJ97192.1 - 1.5e-05 24.7 1.5 1.7e-05 24.5 0.2 1.7 2 0 0 2 2 2 1 PE-PPE domain Lipase_2 PF01674.18 CRJ97192.1 - 0.0036 16.9 0.4 0.56 9.7 0.3 2.2 2 0 0 2 2 2 2 Lipase (class 2) DUF1057 PF06342.12 CRJ97192.1 - 0.0067 15.5 0.0 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_3 PF07859.13 CRJ97192.1 - 0.023 14.6 0.5 5.5 6.8 0.1 2.4 2 0 0 2 2 2 0 alpha/beta hydrolase fold VirJ PF06057.11 CRJ97192.1 - 0.17 11.7 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) AXE1 PF05448.12 CRJ97192.1 - 0.27 9.9 0.4 3 6.4 0.0 2.4 3 0 0 3 3 3 0 Acetyl xylan esterase (AXE1) p450 PF00067.22 CRJ97205.1 - 2.3e-59 201.4 0.0 1.2e-58 199.0 0.0 1.9 2 0 0 2 2 2 1 Cytochrome P450 DUF4407 PF14362.6 CRJ97205.1 - 1.2 8.4 4.7 2.3 7.5 4.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) G_glu_transpept PF01019.21 CRJ97214.1 - 1e-162 542.5 0.1 1.2e-162 542.3 0.1 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Hexapep PF00132.24 CRJ97226.1 - 4.1e-09 35.8 14.2 1.3e-05 24.7 3.4 4.1 3 1 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 CRJ97226.1 - 1.1e-05 25.0 12.3 0.007 16.1 2.0 3.3 2 1 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Complex1_51K PF01512.17 CRJ97236.1 - 6.6e-48 162.4 0.0 1e-47 161.8 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 CRJ97236.1 - 3e-29 100.9 0.9 5.7e-29 100.0 0.1 1.9 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 CRJ97236.1 - 2.6e-09 36.8 0.1 7.3e-09 35.4 0.0 1.8 2 0 0 2 2 2 1 SLBB domain PEX11 PF05648.14 CRJ97248.1 - 1.7e-20 73.4 0.0 2.7e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Peptidase_M43 PF05572.13 CRJ97269.1 - 6.4e-13 48.9 0.0 1.1e-12 48.1 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 CRJ97269.1 - 0.0032 17.6 0.5 0.0045 17.2 0.5 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 CRJ97269.1 - 0.033 13.8 0.0 0.05 13.2 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 CRJ97269.1 - 0.048 14.2 0.0 0.074 13.6 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Metallopep PF12044.8 CRJ97269.1 - 0.26 9.9 0.2 0.4 9.2 0.2 1.2 1 0 0 1 1 1 0 Putative peptidase family DUF1771 PF08590.10 CRJ97289.1 - 0.00061 20.1 11.3 0.0017 18.7 11.3 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) CUE PF02845.16 CRJ97289.1 - 0.048 13.4 0.1 0.1 12.3 0.1 1.5 1 0 0 1 1 1 0 CUE domain NeA_P2 PF12312.8 CRJ97289.1 - 0.073 12.5 0.6 0.15 11.4 0.6 1.5 1 0 0 1 1 1 0 Nepovirus subgroup A polyprotein NPC1_N PF16414.5 CRJ97297.1 - 9.3e-85 284.1 9.7 1.3e-84 283.6 9.7 1.2 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Patched PF02460.18 CRJ97297.1 - 1.1e-76 258.6 18.0 2e-51 175.0 0.7 2.2 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.8 CRJ97297.1 - 5.6e-52 175.6 6.7 5.6e-52 175.6 6.7 2.6 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Aminotran_3 PF00202.21 CRJ97297.1 - 2e-36 125.5 0.0 3.8e-23 81.8 0.0 2.6 3 0 0 3 3 3 2 Aminotransferase class-III MMPL PF03176.15 CRJ97297.1 - 4e-06 26.0 32.9 0.00028 19.9 9.3 2.8 3 0 0 3 3 3 2 MMPL family Folate_rec PF03024.14 CRJ97297.1 - 0.0017 18.3 2.1 0.0035 17.2 2.1 1.4 1 0 0 1 1 1 1 Folate receptor family ACR_tran PF00873.19 CRJ97297.1 - 0.15 9.7 16.5 0.022 12.4 9.8 2.1 2 0 0 2 2 2 0 AcrB/AcrD/AcrF family CENP-F_leu_zip PF10473.9 CRJ97312.1 - 0.00011 22.3 18.3 0.00011 22.3 18.3 8.4 3 1 6 9 9 9 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.6 CRJ97312.1 - 0.00039 19.8 19.3 0.00039 19.8 19.3 7.6 2 1 3 7 7 7 4 Growth-arrest specific micro-tubule binding FAM184 PF15665.5 CRJ97312.1 - 0.0029 17.4 12.3 0.0029 17.4 12.3 7.4 3 2 4 7 7 7 4 Family with sequence similarity 184, A and B Bap31_Bap29_C PF18035.1 CRJ97312.1 - 0.0065 16.4 3.6 0.0065 16.4 3.6 9.9 10 4 1 11 11 11 1 Bap31/Bap29 cytoplasmic coiled-coil domain Flavoprotein PF02441.19 CRJ97332.1 - 1.1e-19 70.8 0.0 1.7e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 Flavoprotein 14-3-3 PF00244.20 CRJ97778.1 - 2.2e-05 24.1 0.2 2.3e-05 24.0 0.2 1.0 1 0 0 1 1 1 1 14-3-3 protein 2-Hacid_dh PF00389.30 CRJ97823.1 - 2e-07 30.8 0.0 2e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 2-Hacid_dh_C PF02826.19 CRJ97823.1 - 1.6e-05 24.4 0.0 2e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF4602 PF15375.6 CRJ97927.1 - 0.11 12.8 3.1 0.13 12.5 3.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4602) Q_salvage PF10343.9 CRJ98160.1 - 5.3e-58 196.8 0.0 5.8e-58 196.7 0.0 1.0 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family Glyco_hydro_61 PF03443.14 CRJ98413.1 - 4.1e-17 62.8 0.1 4.3e-17 62.7 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Adaptin_N PF01602.20 CRJ98525.1 - 5.9e-11 41.6 0.1 5.9e-11 41.6 0.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region G-patch_2 PF12656.7 CRJ98525.1 - 0.06 13.4 0.0 0.087 12.9 0.0 1.2 1 0 0 1 1 1 0 G-patch domain RINT1_TIP1 PF04437.13 CRJ98633.1 - 7e-97 325.4 0.0 4.8e-54 184.1 0.0 2.0 2 0 0 2 2 2 2 RINT-1 / TIP-1 family CorA PF01544.18 CRJ98658.1 - 0.00037 19.9 4.0 0.0014 18.0 3.7 1.9 1 1 1 2 2 2 1 CorA-like Mg2+ transporter protein PNP_UDP_1 PF01048.20 CRJ98663.1 - 1e-05 24.9 0.1 1.1e-05 24.9 0.1 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Glyco_hydro_47 PF01532.20 CRJ98671.1 - 6.3e-181 602.3 0.0 7.8e-181 601.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Pkinase PF00069.25 CRJ98676.1 - 7.7e-64 215.6 0.0 1.1e-63 215.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRJ98676.1 - 6.1e-48 163.3 0.0 9.4e-48 162.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CRJ98676.1 - 5.3e-09 35.8 0.0 3.6e-07 29.8 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 CRJ98676.1 - 0.0023 17.3 0.0 0.0078 15.6 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CRJ98676.1 - 0.0081 15.0 0.0 0.015 14.1 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Sugar_tr PF00083.24 CRJ98679.1 - 1.1e-68 232.2 8.2 1.5e-68 231.7 8.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Glyco_hydro_5_C PF18564.1 CRJ98679.1 - 6.9e-16 58.6 0.0 1.6e-15 57.4 0.0 1.6 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 CRJ98679.1 - 1.2e-11 44.6 1.8 8.6e-08 31.9 0.1 2.6 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) MFS_1 PF07690.16 CRJ98679.1 - 2e-10 40.2 53.5 1.5e-09 37.3 32.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ank_2 PF12796.7 CRJ98687.1 - 2.7e-19 69.5 0.1 1.1e-10 41.9 0.0 2.9 2 1 1 3 3 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 CRJ98687.1 - 6.9e-14 51.6 1.6 0.00013 22.2 0.0 4.7 5 0 0 5 5 4 3 Ankyrin repeat Ank_5 PF13857.6 CRJ98687.1 - 1.1e-13 51.1 1.1 7.5e-07 29.3 0.0 3.9 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 CRJ98687.1 - 6.5e-13 48.9 0.2 3.4e-06 27.5 0.0 4.4 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CRJ98687.1 - 5.4e-11 41.7 0.6 1.2e-06 28.4 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat TPR_12 PF13424.6 CRJ98687.1 - 1.3e-07 31.8 0.1 0.0015 18.8 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 CRJ98687.1 - 3.4e-05 24.3 1.5 0.059 14.2 0.1 3.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 CRJ98687.1 - 5.5e-05 22.7 1.4 9.5e-05 21.9 0.3 1.9 2 0 0 2 2 2 1 MalT-like TPR region TPR_19 PF14559.6 CRJ98687.1 - 0.00012 22.5 1.3 0.0014 19.1 0.1 2.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 CRJ98687.1 - 0.00032 20.5 0.4 0.86 9.6 0.1 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 CRJ98687.1 - 0.00099 19.1 0.2 0.035 14.2 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 CRJ98687.1 - 0.0016 18.3 0.4 0.44 10.7 0.1 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 CRJ98687.1 - 0.0019 17.9 0.1 0.039 13.8 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 CRJ98687.1 - 0.0073 16.4 0.0 0.084 13.1 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 CRJ98687.1 - 0.0099 16.5 0.1 5.3 7.9 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat HTH_22 PF13309.6 CRJ98687.1 - 0.13 12.4 0.1 1.4 9.1 0.0 2.7 3 0 0 3 3 3 0 HTH domain Bacillus_HBL PF05791.11 CRJ98687.1 - 0.26 11.1 2.6 0.37 10.6 1.8 1.7 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) RIX1 PF08167.12 CRJ98691.1 - 4.6e-62 209.1 0.0 6.6e-62 208.6 0.0 1.2 1 0 0 1 1 1 1 rRNA processing/ribosome biogenesis TPR_14 PF13428.6 CRJ98696.1 - 5.8e-07 29.8 13.7 0.18 12.7 0.1 7.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 CRJ98696.1 - 1.2e-05 25.7 0.7 0.85 10.2 0.1 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 CRJ98696.1 - 4.4e-05 23.3 8.5 3.9 7.8 0.0 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 CRJ98696.1 - 0.0061 16.7 0.4 2.9 8.3 0.0 4.5 6 0 0 6 6 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CRJ98696.1 - 0.0063 16.7 0.4 1.1 9.5 0.1 3.2 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 CRJ98696.1 - 0.046 13.8 0.3 45 4.4 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 CRJ98696.1 - 0.15 12.4 10.7 3 8.2 0.1 5.8 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_6 PF13174.6 CRJ98696.1 - 0.28 11.9 1.0 1.3e+02 3.5 0.0 4.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 CRJ98696.1 - 0.47 11.1 0.1 0.47 11.1 0.1 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat FMN_dh PF01070.18 CRJ98722.1 - 1.2e-25 90.3 0.0 1.6e-25 89.9 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase SGL PF08450.12 CRJ98732.1 - 1.2e-65 221.6 0.1 1.5e-65 221.2 0.1 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 CRJ98732.1 - 0.0019 18.3 0.0 0.004 17.3 0.0 1.5 1 0 0 1 1 1 1 Arylesterase Reg_prop PF07494.11 CRJ98732.1 - 0.019 15.2 0.5 1.7 9.2 0.0 2.9 2 0 0 2 2 2 0 Two component regulator propeller Phytase-like PF13449.6 CRJ98732.1 - 0.1 12.5 0.1 0.51 10.2 0.1 2.1 1 1 0 1 1 1 0 Esterase-like activity of phytase DUF3194 PF11419.8 CRJ98732.1 - 0.19 12.1 0.7 0.33 11.3 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3194) bZIP_2 PF07716.15 CRJ98739.1 - 0.00013 22.0 5.7 0.00023 21.2 5.5 1.6 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 CRJ98739.1 - 0.00056 20.0 7.3 0.00095 19.2 7.3 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 CRJ98739.1 - 0.0023 18.4 7.4 0.0042 17.6 7.4 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor Cnn_1N PF07989.11 CRJ98739.1 - 0.062 13.5 0.7 0.098 12.8 0.7 1.4 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 YabA PF06156.13 CRJ98739.1 - 0.088 13.5 0.1 0.14 12.9 0.1 1.3 1 0 0 1 1 1 0 Initiation control protein YabA Aldedh PF00171.22 CRJ98746.1 - 2.3e-138 461.6 0.0 1.4e-125 419.4 0.0 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family Dcc1 PF09724.9 CRJ98746.1 - 0.092 12.0 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Sister chromatid cohesion protein Dcc1 PaaB PF06243.11 CRJ98752.1 - 0.13 12.5 0.3 0.23 11.7 0.3 1.4 1 0 0 1 1 1 0 Phenylacetic acid degradation B TFIIA PF03153.13 CRJ98769.1 - 0.00042 20.4 17.8 0.00048 20.2 17.8 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Plasmodium_Vir PF05795.11 CRJ98769.1 - 0.067 12.6 0.5 0.071 12.5 0.5 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Med15 PF09606.10 CRJ98769.1 - 0.071 11.8 20.5 0.081 11.6 20.5 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Gastrin PF00918.17 CRJ98769.1 - 0.13 13.3 7.4 0.19 12.7 7.4 1.2 1 0 0 1 1 1 0 Gastrin/cholecystokinin family DUF2722 PF10846.8 CRJ98769.1 - 0.16 10.9 18.8 0.18 10.7 18.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) GREB1 PF15782.5 CRJ98769.1 - 0.17 9.0 6.3 0.18 8.9 6.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF1178 PF06676.11 CRJ98769.1 - 0.46 10.9 8.8 0.66 10.3 8.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1178) LMBR1 PF04791.16 CRJ98769.1 - 0.51 9.2 0.9 0.53 9.1 0.9 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein MTP18 PF10558.9 CRJ98769.1 - 0.66 9.9 3.2 0.95 9.4 3.2 1.2 1 0 0 1 1 1 0 Mitochondrial 18 KDa protein (MTP18) Pex14_N PF04695.13 CRJ98769.1 - 0.8 10.3 13.9 1.1 9.9 13.9 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Neur_chan_memb PF02932.16 CRJ98769.1 - 0.99 9.4 3.3 1.1 9.2 3.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Suf PF05843.14 CRJ98769.1 - 2.6 8.0 10.9 3.2 7.7 10.9 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) MAJIN PF15077.6 CRJ98769.1 - 2.6 7.8 7.1 3.1 7.5 7.1 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein TERB2 PF15101.6 CRJ98769.1 - 2.7 8.0 13.1 4 7.4 13.1 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 CLN3 PF02487.17 CRJ98769.1 - 3.4 6.6 3.6 4 6.4 3.6 1.1 1 0 0 1 1 1 0 CLN3 protein Spt20 PF12090.8 CRJ98769.1 - 3.7 7.1 30.2 4.8 6.7 30.2 1.1 1 0 0 1 1 1 0 Spt20 family Presenilin PF01080.17 CRJ98769.1 - 4.1 6.0 11.3 5.4 5.7 11.3 1.1 1 0 0 1 1 1 0 Presenilin DUF4834 PF16118.5 CRJ98769.1 - 5.7 8.0 10.8 8.8 7.4 10.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Activator_LAG-3 PF11498.8 CRJ98769.1 - 6.9 5.5 34.1 9 5.1 34.1 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Peptidase_M18 PF02127.15 CRJ98776.1 - 3.7e-57 194.1 0.0 5.1e-57 193.6 0.0 1.1 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) SGL PF08450.12 CRJ98776.1 - 7.1e-41 140.4 0.1 1.3e-40 139.5 0.1 1.4 2 0 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 CRJ98776.1 - 0.002 18.3 0.0 0.005 17.0 0.0 1.6 1 0 0 1 1 1 1 Arylesterase Peptidase_M42 PF05343.14 CRJ98776.1 - 0.0026 16.8 0.0 0.004 16.2 0.0 1.3 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase bZIP_1 PF00170.21 CRJ98784.1 - 0.0013 18.8 7.3 0.002 18.1 7.3 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 CRJ98784.1 - 0.0043 17.5 7.3 0.0091 16.5 7.3 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.15 CRJ98784.1 - 0.0084 16.2 10.4 0.016 15.3 10.4 1.5 1 0 0 1 1 1 1 Basic region leucine zipper Cnn_1N PF07989.11 CRJ98784.1 - 0.11 12.6 0.6 0.19 11.9 0.6 1.4 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 YabA PF06156.13 CRJ98784.1 - 0.19 12.4 0.1 0.32 11.7 0.1 1.3 1 0 0 1 1 1 0 Initiation control protein YabA Aldedh PF00171.22 CRJ98788.1 - 1.7e-132 442.3 0.1 5.1e-111 371.4 0.0 2.8 1 1 1 2 2 2 2 Aldehyde dehydrogenase family Dcc1 PF09724.9 CRJ98788.1 - 0.098 11.9 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Sister chromatid cohesion protein Dcc1 Spt20 PF12090.8 CRJ98809.1 - 3.4 7.2 7.5 4.5 6.8 7.5 1.1 1 0 0 1 1 1 0 Spt20 family Peptidase_M18 PF02127.15 CRJ98815.1 - 6e-173 575.6 0.0 1.1e-171 571.4 0.0 2.0 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 CRJ98815.1 - 2.6e-06 26.7 0.0 0.011 14.8 0.0 3.0 2 1 1 3 3 3 3 M42 glutamyl aminopeptidase Whi5 PF08528.11 CRJ98830.1 - 9.7e-10 37.9 0.1 1.7e-09 37.1 0.1 1.4 1 0 0 1 1 1 1 Whi5 like CD52 PF15116.6 CRJ98830.1 - 1.7 8.8 8.8 0.24 11.4 1.4 2.6 2 0 0 2 2 2 0 CAMPATH-1 antigen RTA1 PF04479.13 CRJ98845.1 - 1.2e-62 211.2 12.2 1.2e-62 211.2 12.2 1.4 2 0 0 2 2 2 1 RTA1 like protein FAD_binding_4 PF01565.23 CRJ98864.1 - 1.7e-23 82.9 0.5 3.1e-23 82.0 0.5 1.5 1 0 0 1 1 1 1 FAD binding domain Beta_helix PF13229.6 CRJ98877.1 - 0.044 13.6 30.1 1.2 8.9 22.4 2.5 1 1 1 2 2 2 0 Right handed beta helix region DUF4484 PF14831.6 CRJ98884.1 - 1.2e-65 221.6 0.4 2e-65 220.8 0.1 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4484) Importin_rep_4 PF18808.1 CRJ98884.1 - 0.13 12.6 1.5 0.3 11.4 1.5 1.6 1 0 0 1 1 1 0 Importin repeat NOA36 PF06524.12 CRJ98884.1 - 0.24 10.7 3.0 0.47 9.7 3.0 1.4 1 0 0 1 1 1 0 NOA36 protein DUF1771 PF08590.10 CRJ98891.1 - 5.7e-22 77.9 7.2 5.7e-22 77.9 7.2 2.8 2 1 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.21 CRJ98891.1 - 2.1e-08 34.4 0.2 2.1e-08 34.4 0.2 2.4 2 1 1 3 3 3 1 Smr domain Suf PF05843.14 CRJ98891.1 - 0.036 14.0 3.7 0.064 13.2 3.7 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4407 PF14362.6 CRJ98891.1 - 1.4 8.2 13.9 0.021 14.2 1.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Cys_Met_Meta_PP PF01053.20 CRJ98897.1 - 5.8e-59 199.5 0.6 7.1e-59 199.3 0.6 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 CRJ98897.1 - 5.4e-07 29.3 0.5 7.5e-07 28.8 0.5 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 CRJ98897.1 - 4.9e-06 26.0 0.1 6.6e-06 25.5 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 CRJ98897.1 - 1.2e-05 24.4 0.3 1.4e-05 24.2 0.3 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 CRJ98897.1 - 0.00094 18.5 0.1 0.0016 17.8 0.1 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Brix PF04427.18 CRJ98910.1 - 2.9e-35 122.1 0.4 3.7e-35 121.8 0.0 1.3 2 0 0 2 2 2 1 Brix domain Rsm22 PF09243.10 CRJ98919.1 - 7.8e-23 81.1 0.1 1.3e-21 77.1 0.1 2.3 1 1 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 PIG-U PF06728.13 CRJ98919.1 - 1.2e-07 31.2 2.7 2e-07 30.4 2.7 1.3 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Mpv17_PMP22 PF04117.12 CRJ98919.1 - 1.7e-07 31.4 0.4 1.7e-07 31.4 0.4 2.3 2 0 0 2 2 2 1 Mpv17 / PMP22 family Dabb PF07876.12 CRJ98930.1 - 0.0057 17.2 0.0 0.0057 17.2 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain TP_methylase PF00590.20 CRJ98937.1 - 1.6e-47 162.2 1.0 3.9e-47 160.9 1.0 1.7 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 CRJ98937.1 - 4.5e-13 49.5 0.0 1.2e-12 48.2 0.0 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_M PF14824.6 CRJ98937.1 - 8.1e-11 41.2 0.0 1.7e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Sirohm_synth_C PF14823.6 CRJ98937.1 - 6.2e-10 38.6 0.2 9.8e-09 34.7 0.2 2.2 1 1 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal SpoU_sub_bind PF08032.12 CRJ98937.1 - 0.092 13.0 0.0 0.26 11.6 0.0 1.8 1 0 0 1 1 1 0 RNA 2'-O ribose methyltransferase substrate binding AATase PF07247.12 CRJ98951.1 - 0.29 9.6 0.0 2 6.9 0.0 1.9 1 1 0 1 1 1 0 Alcohol acetyltransferase F-box-like PF12937.7 CRJ98968.1 - 0.04 13.8 0.0 0.08 12.9 0.0 1.5 1 0 0 1 1 1 0 F-box-like Phage_portal PF04860.12 CRJ98974.1 - 0.0016 17.7 0.0 0.0022 17.2 0.0 1.2 1 0 0 1 1 1 1 Phage portal protein RHH_5 PF07878.11 CRJ98974.1 - 0.13 12.2 0.0 0.34 10.8 0.0 1.7 1 0 0 1 1 1 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 AcetDehyd-dimer PF09290.11 CRJ98974.1 - 0.18 12.0 0.0 0.32 11.2 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic acetaldehyde dehydrogenase, dimerisation Amino_oxidase PF01593.24 CRJ98987.1 - 2.6e-59 201.7 0.4 6.6e-45 154.2 0.0 2.0 1 1 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CRJ98987.1 - 7.1e-11 42.2 0.5 1.5e-10 41.1 0.5 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 CRJ98987.1 - 0.00024 21.6 0.4 0.53 10.9 0.2 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CRJ98987.1 - 0.0005 19.7 1.7 0.046 13.3 0.8 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.22 CRJ98987.1 - 0.003 16.7 0.2 0.0044 16.1 0.2 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 CRJ98987.1 - 0.0045 16.3 0.1 0.076 12.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CRJ98987.1 - 0.005 16.1 0.2 0.0085 15.4 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 CRJ98987.1 - 0.034 13.4 0.4 0.16 11.2 0.3 2.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 CRJ98987.1 - 0.05 12.9 0.1 0.21 10.9 0.1 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 CRJ98987.1 - 0.14 11.4 1.6 0.31 10.4 1.4 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CRJ98995.1 - 2.8e-14 53.1 0.0 6.7e-14 51.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 CRJ98995.1 - 1.1e-06 28.3 1.7 1.8e-05 24.2 0.3 3.1 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.24 CRJ98995.1 - 0.00024 20.8 0.6 0.0029 17.2 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CRJ98995.1 - 0.0043 16.3 0.0 0.031 13.5 0.0 2.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CRJ98995.1 - 0.0047 16.9 0.3 0.16 12.0 0.0 3.2 2 2 2 4 4 4 1 FAD-NAD(P)-binding Prenylcys_lyase PF07156.14 CRJ98995.1 - 0.024 13.7 0.0 0.036 13.2 0.0 1.2 1 0 0 1 1 1 0 Prenylcysteine lyase F420_oxidored PF03807.17 CRJ98995.1 - 0.029 15.0 0.0 4 8.1 0.0 2.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent baeRF_family12 PF18856.1 CRJ98995.1 - 0.048 14.2 0.0 0.1 13.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 12 FAD_binding_3 PF01494.19 CRJ98995.1 - 0.049 12.9 0.1 0.15 11.2 0.0 1.9 2 1 1 3 3 3 0 FAD binding domain DUF2834 PF11196.8 CRJ99004.1 - 1.2e-08 35.2 21.3 0.0002 21.6 9.5 4.3 4 1 0 4 4 4 2 Protein of unknown function (DUF2834) PBP1_TM PF14812.6 CRJ99004.1 - 0.055 13.8 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4632 PF15451.6 CRJ99004.1 - 0.077 13.1 0.6 1.4 9.1 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4632) Methyltransf_25 PF13649.6 CRJ99013.1 - 0.0032 18.1 0.0 0.01 16.5 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain tRNA_anti-codon PF01336.25 CRJ99152.1 - 2.9e-05 24.0 0.0 4.7e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.6 CRJ99152.1 - 0.1 12.8 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Mito_carr PF00153.27 CRJ99464.1 - 3.3e-08 33.4 0.0 3.4e-08 33.3 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial carrier protein Tti2 PF10521.9 CRJ99567.1 - 0.03 13.8 0.0 0.038 13.5 0.0 1.1 1 0 0 1 1 1 0 Tti2 family Cyt-b5 PF00173.28 CRJ99659.1 - 2.2e-10 40.5 0.1 2.5e-10 40.4 0.1 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Nuclease_act PF08133.11 CRJ99659.1 - 0.048 13.8 0.5 0.081 13.1 0.0 1.6 2 0 0 2 2 2 0 Anticodon nuclease activator family HMGL-like PF00682.19 CRK00124.1 - 5.2e-18 65.5 0.1 6e-18 65.3 0.1 1.0 1 0 0 1 1 1 1 HMGL-like PYC_OADA PF02436.18 CRK00124.1 - 1e-06 28.6 0.4 1.3e-06 28.3 0.4 1.2 1 0 0 1 1 1 1 Conserved carboxylase domain BAH PF01426.18 CRK00257.1 - 3.7e-07 30.0 0.0 0.012 15.4 0.0 2.5 2 0 0 2 2 2 2 BAH domain DUF1376 PF07120.11 CRK00257.1 - 0.00016 22.0 0.2 1.5 9.1 0.0 3.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1376) PHD PF00628.29 CRK00257.1 - 0.0053 16.6 3.5 0.013 15.4 3.5 1.6 1 0 0 1 1 1 1 PHD-finger zf-RING-like PF08746.11 CRK00257.1 - 0.033 14.5 0.6 0.075 13.4 0.6 1.6 1 0 0 1 1 1 0 RING-like domain zf-HC5HC2H PF13771.6 CRK00257.1 - 0.034 14.4 1.4 0.04 14.2 0.1 1.7 2 0 0 2 2 2 0 PHD-like zinc-binding domain BPA_C PF18040.1 CRK00257.1 - 0.065 13.2 0.0 16 5.5 0.0 2.6 2 0 0 2 2 2 0 beta porphyranase A C-terminal Peptidase_M24 PF00557.24 CRK00272.1 - 9.6e-09 35.2 0.0 1.3e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Epimerase PF01370.21 CRK00282.1 - 6.7e-17 61.8 0.0 9.1e-17 61.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 CRK00282.1 - 2.3e-06 26.9 0.0 3.5e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 CRK00282.1 - 8.4e-06 25.4 0.0 1.2e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 CRK00282.1 - 0.0014 17.7 0.0 0.0033 16.5 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 CRK00282.1 - 0.027 14.7 0.0 0.052 13.8 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Ldh_1_N PF00056.23 CRK00282.1 - 0.1 12.7 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain AhpC-TSA_2 PF13911.6 CRK00299.1 - 1.8e-18 66.7 0.0 1.1e-17 64.2 0.0 2.1 2 0 0 2 2 2 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 CRK00299.1 - 0.023 14.6 0.0 0.062 13.2 0.0 1.7 1 1 0 1 1 1 0 AhpC/TSA family Kinesin_assoc PF16183.5 CRK00305.1 - 0.00015 21.9 0.1 0.0021 18.3 0.0 2.1 1 1 1 2 2 2 1 Kinesin-associated FadA PF09403.10 CRK00305.1 - 0.31 11.5 2.9 0.31 11.5 0.9 1.9 2 0 0 2 2 2 0 Adhesion protein FadA ABC_tran_CTD PF16326.5 CRK00305.1 - 1.4 9.2 8.3 21 5.5 0.2 3.3 3 0 0 3 3 3 0 ABC transporter C-terminal domain APH PF01636.23 CRK00314.1 - 2.7e-11 43.9 0.0 5.3e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CRK00314.1 - 0.023 14.3 0.0 0.053 13.1 0.0 1.6 2 0 0 2 2 2 0 Choline/ethanolamine kinase DDE_Tnp_IS66 PF03050.14 CRK00314.1 - 0.039 13.4 0.1 0.06 12.8 0.1 1.2 1 0 0 1 1 1 0 Transposase IS66 family NmrA PF05368.13 CRK00329.1 - 1.8e-15 57.1 0.0 3e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 CRK00329.1 - 4.3e-15 56.1 0.0 6.5e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 CRK00329.1 - 2.2e-13 50.3 0.1 5.6e-13 48.9 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CRK00329.1 - 1.3e-09 37.5 0.1 2.6e-09 36.5 0.2 1.5 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 CRK00329.1 - 8.2e-07 28.7 0.1 1.5e-06 27.9 0.1 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 CRK00329.1 - 1.8e-06 27.2 0.0 0.00022 20.4 0.0 2.3 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 CRK00329.1 - 2.1e-05 24.1 0.0 3.4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 CRK00329.1 - 0.0043 16.3 0.3 0.39 9.8 0.3 2.8 1 1 1 2 2 2 1 Male sterility protein adh_short_C2 PF13561.6 CRK00329.1 - 0.012 15.2 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase ApbA PF02558.16 CRK00329.1 - 0.049 13.3 0.0 0.32 10.6 0.0 2.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA KR PF08659.10 CRK00329.1 - 0.05 13.5 0.0 0.73 9.7 0.0 2.2 2 0 0 2 2 2 0 KR domain DapB_N PF01113.20 CRK00329.1 - 0.063 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.15 CRK00329.1 - 0.07 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein N6-adenineMlase PF10237.9 CRK00341.1 - 8e-21 74.5 0.0 1.1e-20 74.0 0.0 1.2 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase FAD-oxidase_C PF02913.19 CRK00341.1 - 0.045 13.4 0.2 0.058 13.0 0.2 1.1 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain UCH PF00443.29 CRK00349.1 - 1.7e-46 158.8 1.7 2.7e-46 158.2 1.7 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CRK00349.1 - 1.3e-20 74.3 14.9 1.5e-19 70.7 9.2 2.5 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 CRK00349.1 - 3.3e-06 27.3 0.3 3.3e-06 27.3 0.3 2.4 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein Flu_PB1 PF00602.17 CRK00349.1 - 0.019 13.1 0.2 0.068 11.3 0.2 1.7 1 1 0 1 1 1 0 Influenza RNA-dependent RNA polymerase subunit PB1 zf_C2H2_ZHX PF18387.1 CRK00349.1 - 0.027 14.1 1.3 0.05 13.3 0.1 2.2 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain Peptidase_C98 PF15499.6 CRK00349.1 - 0.94 8.9 5.8 3.5 7.0 3.6 2.5 2 1 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase BLACT_WH PF17778.1 CRK00358.1 - 1.7e-18 66.4 0.1 3.6e-18 65.3 0.1 1.6 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B PF00753.27 CRK00358.1 - 7.8e-15 55.4 4.9 8.8e-13 48.7 4.9 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CRK00358.1 - 1.7e-07 31.0 0.1 3.4e-07 30.0 0.1 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 CRK00358.1 - 0.00069 19.6 0.1 0.0011 18.9 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 CRK00358.1 - 0.097 12.1 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain Ytp1 PF10355.9 CRK00365.1 - 4.1e-108 360.8 0.6 5.3e-108 360.4 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) Rsa3 PF14615.6 CRK00375.1 - 1.5e-19 69.3 1.1 2.2e-19 68.7 1.1 1.3 1 0 0 1 1 1 1 Ribosome-assembly protein 3 CBS PF00571.28 CRK00381.1 - 5.7e-15 55.5 1.0 5.9e-05 23.4 0.0 4.5 5 0 0 5 5 5 3 CBS domain E_Pc_C PF06752.12 CRK00381.1 - 1.2 9.2 4.7 1.8 8.6 4.7 1.2 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus Importin_rep_4 PF18808.1 CRK00389.1 - 9.2e-33 112.4 3.6 6.2e-31 106.6 2.0 3.3 2 0 0 2 2 2 1 Importin repeat HEAT_EZ PF13513.6 CRK00389.1 - 1.7e-20 73.1 6.9 2.5e-10 40.7 0.1 7.6 5 1 2 7 7 7 3 HEAT-like repeat PAS_3 PF08447.12 CRK00389.1 - 2.3e-19 69.5 0.0 1.6e-11 44.3 0.0 3.7 3 0 0 3 3 3 3 PAS fold Importin_rep_5 PF18816.1 CRK00389.1 - 1.2e-18 67.1 0.8 1.2e-18 67.1 0.8 2.6 3 0 0 3 3 2 1 Importin repeat PAS_9 PF13426.7 CRK00389.1 - 1.4e-18 67.1 0.0 2.8e-10 40.4 0.0 3.9 3 0 0 3 3 3 3 PAS domain HEAT_2 PF13646.6 CRK00389.1 - 1.4e-17 63.8 12.8 2.5e-07 31.0 0.1 8.1 3 3 4 7 7 7 3 HEAT repeats HEAT PF02985.22 CRK00389.1 - 1.9e-16 58.8 13.7 0.0058 16.8 0.0 10.4 12 0 0 12 12 9 4 HEAT repeat GATA PF00320.27 CRK00389.1 - 1.2e-14 53.6 8.9 2.2e-14 52.8 8.9 1.5 1 0 0 1 1 1 1 GATA zinc finger PAS PF00989.25 CRK00389.1 - 3.4e-14 52.8 0.0 2.1e-05 24.5 0.0 4.0 3 0 0 3 3 3 3 PAS fold Vac14_Fab1_bd PF12755.7 CRK00389.1 - 2.6e-09 37.5 0.1 0.35 11.5 0.0 6.8 4 2 4 8 8 7 2 Vacuolar 14 Fab1-binding region RIX1 PF08167.12 CRK00389.1 - 1.7e-08 34.5 0.0 4.1e-06 26.7 0.0 4.0 3 0 0 3 3 3 1 rRNA processing/ribosome biogenesis CLASP_N PF12348.8 CRK00389.1 - 3.6e-07 30.0 1.2 0.029 13.9 0.1 5.8 5 1 0 6 6 6 1 CLASP N terminal MMS19_C PF12460.8 CRK00389.1 - 5.3e-06 25.8 5.3 5.3e-05 22.5 0.0 3.7 4 0 0 4 4 4 1 RNAPII transcription regulator C-terminal PAS_4 PF08448.10 CRK00389.1 - 8.2e-06 26.0 0.0 0.094 13.0 0.0 3.9 3 0 0 3 3 3 1 PAS fold Cnd1 PF12717.7 CRK00389.1 - 1.6e-05 25.0 0.2 1.6 8.8 0.0 5.2 4 2 2 6 6 6 1 non-SMC mitotic condensation complex subunit 1 PAS_2 PF08446.11 CRK00389.1 - 0.00051 20.7 0.0 0.12 13.0 0.0 3.5 3 0 0 3 3 3 1 PAS fold Adaptin_N PF01602.20 CRK00389.1 - 0.0025 16.5 2.6 0.017 13.7 0.1 3.0 2 1 1 3 3 3 1 Adaptin N terminal region RTP1_C1 PF10363.9 CRK00389.1 - 0.0043 17.2 1.3 0.075 13.2 0.1 3.7 5 0 0 5 5 4 1 Required for nuclear transport of RNA pol II C-terminus 1 IBN_N PF03810.19 CRK00389.1 - 0.0045 16.9 0.2 0.029 14.3 0.1 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain Arm PF00514.23 CRK00389.1 - 0.0074 16.3 6.3 2.8 8.1 0.0 4.6 5 0 0 5 5 3 2 Armadillo/beta-catenin-like repeat Cohesin_HEAT PF12765.7 CRK00389.1 - 0.012 15.9 0.0 2.9 8.3 0.0 2.8 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion TFCD_C PF12612.8 CRK00389.1 - 0.013 15.3 0.2 1.6 8.5 0.0 3.5 3 1 1 4 4 3 0 Tubulin folding cofactor D C terminal DNA_alkylation PF08713.11 CRK00389.1 - 0.048 13.4 0.8 0.28 10.8 0.0 2.6 3 0 0 3 3 3 0 DNA alkylation repair enzyme Telomere_reg-2 PF10193.9 CRK00389.1 - 0.092 13.2 3.7 0.39 11.2 0.3 3.4 3 0 0 3 3 3 0 Telomere length regulation protein Dopey_N PF04118.14 CRK00389.1 - 0.17 11.0 2.2 2.5 7.1 0.0 2.9 3 0 0 3 3 3 0 Dopey, N-terminal V-ATPase_H_N PF03224.14 CRK00389.1 - 0.21 10.8 4.2 0.97 8.7 0.1 3.1 2 1 1 3 3 3 0 V-ATPase subunit H Cnd3 PF12719.7 CRK00389.1 - 0.22 10.6 2.2 9.4 5.3 0.0 3.7 3 1 1 4 4 4 0 Nuclear condensing complex subunits, C-term domain NYN PF01936.18 CRK00407.1 - 0.01 16.3 0.0 0.021 15.3 0.0 1.5 1 0 0 1 1 1 0 NYN domain Bromodomain PF00439.25 CRK00421.1 - 4.2e-40 135.7 2.2 3.2e-19 68.8 0.4 2.6 2 0 0 2 2 2 2 Bromodomain BAH PF01426.18 CRK00421.1 - 3.3e-20 72.2 1.6 5.8e-20 71.4 0.4 2.1 2 0 0 2 2 2 1 BAH domain OTU PF02338.19 CRK00430.1 - 0.00026 21.5 0.0 0.00051 20.5 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease EI24 PF07264.11 CRK00438.1 - 8.7e-15 55.4 1.1 2.8e-06 27.7 0.7 2.2 1 1 1 2 2 2 2 Etoposide-induced protein 2.4 (EI24) Inp1 PF12634.7 CRK00443.1 - 2.9e-42 143.9 0.0 7.8e-42 142.5 0.0 1.8 1 0 0 1 1 1 1 Inheritance of peroxisomes protein 1 Pyr_redox_2 PF07992.14 CRK00456.1 - 3e-21 75.9 0.4 7e-21 74.7 0.4 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CRK00456.1 - 1.1e-06 28.7 2.5 0.0058 16.6 0.1 3.0 3 0 0 3 3 3 2 FAD-NAD(P)-binding DAO PF01266.24 CRK00456.1 - 2.1e-05 24.3 5.8 5.7e-05 22.9 0.5 2.7 1 1 2 3 3 3 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 CRK00456.1 - 2.6e-05 23.4 0.3 0.045 12.8 0.1 2.2 1 1 1 2 2 2 2 Lycopene cyclase protein FAD_binding_3 PF01494.19 CRK00456.1 - 9.9e-05 21.7 0.0 0.00021 20.7 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 CRK00456.1 - 0.00015 20.6 0.0 0.0049 15.6 0.0 2.3 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 CRK00456.1 - 0.00021 20.6 0.0 0.18 11.0 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CRK00456.1 - 0.00024 21.2 0.1 0.0006 20.0 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CRK00456.1 - 0.00043 19.6 0.0 0.001 18.4 0.0 1.5 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 CRK00456.1 - 0.001 18.3 0.1 0.28 10.2 0.1 2.3 1 1 1 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 CRK00456.1 - 0.001 18.2 3.3 0.0046 16.1 0.1 2.7 2 1 1 3 3 3 1 FAD binding domain Trp_halogenase PF04820.14 CRK00456.1 - 0.019 13.8 0.0 0.029 13.2 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.27 CRK00456.1 - 0.026 15.1 0.2 3.3 8.3 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CRK00456.1 - 0.037 13.4 0.3 0.11 11.8 0.1 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase Glu_dehyd_C PF16912.5 CRK00456.1 - 0.045 13.2 0.2 4.4 6.7 0.0 2.4 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus K_oxygenase PF13434.6 CRK00456.1 - 0.14 11.3 0.0 13 4.8 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Mito_carr PF00153.27 CRK00460.1 - 3.7e-47 158.2 6.8 7.5e-20 70.7 0.1 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF1870 PF08965.10 CRK00460.1 - 0.17 11.9 0.0 2.4 8.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1870) SNF2_N PF00176.23 CRK00463.1 - 5.9e-56 189.7 0.0 1.3e-55 188.6 0.0 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.10 CRK00463.1 - 4.5e-53 180.1 0.6 2.2e-52 177.9 0.9 1.9 2 0 0 2 2 2 1 Rad54 N terminal Helicase_C PF00271.31 CRK00463.1 - 5.9e-16 58.8 0.0 1.2e-15 57.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CRK00463.1 - 1.8e-07 31.3 0.0 3.8e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 CRK00463.1 - 0.00031 20.0 0.0 0.0017 17.6 0.0 2.0 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 CRK00463.1 - 0.23 11.1 0.0 1 9.0 0.0 2.0 1 1 0 1 1 1 0 SWI2/SNF2 ATPase Glyco_transf_24 PF18404.1 CRK00467.1 - 2.3e-147 489.5 2.4 3.7e-147 488.9 2.4 1.3 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 CRK00467.1 - 4e-70 236.7 0.0 8.2e-70 235.7 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_15 PF18403.1 CRK00467.1 - 2.3e-57 194.4 0.0 3.4e-54 184.0 0.0 2.6 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_13 PF18401.1 CRK00467.1 - 1.6e-44 151.1 0.2 6.4e-43 145.9 0.2 2.8 3 0 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_12 PF18400.1 CRK00467.1 - 2.6e-44 151.4 0.1 7.1e-44 150.0 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 CRK00467.1 - 1e-17 64.2 0.0 1.8e-08 34.5 0.0 2.5 1 1 1 2 2 2 2 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.20 CRK00467.1 - 1.2e-05 25.0 0.1 2.5e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 Coatomer_WDAD PF04053.14 CRK00472.1 - 1.1e-140 469.6 0.0 1.9e-140 468.9 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 CRK00472.1 - 5.1e-98 328.5 0.0 7.1e-98 328.0 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 CRK00472.1 - 6.3e-35 118.6 18.3 7.3e-08 33.0 0.4 7.8 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK00472.1 - 6.2e-09 36.0 0.9 0.0019 18.5 0.0 5.8 3 2 5 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CRK00472.1 - 0.012 14.3 6.0 0.85 8.2 0.1 3.5 2 1 2 4 4 4 0 Nucleoporin Nup120/160 Clathrin PF00637.20 CRK00472.1 - 0.13 12.1 0.0 0.7 9.8 0.0 2.2 1 1 0 1 1 1 0 Region in Clathrin and VPS FIVAR PF07554.13 CRK00472.1 - 2.6 8.9 4.3 36 5.2 0.3 2.6 2 0 0 2 2 2 0 FIVAR domain CSN8_PSD8_EIF3K PF10075.9 CRK00478.1 - 1e-18 67.7 0.0 1.7e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 CRK00478.1 - 0.064 12.6 0.0 0.092 12.1 0.0 1.3 1 0 0 1 1 1 0 SAC3/GANP family Peptidase_M28 PF04389.17 CRK00489.1 - 2.2e-34 118.9 0.0 3.7e-34 118.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Sel1 PF08238.12 CRK00489.1 - 7.9e-16 58.1 25.5 8.6e-07 29.4 0.1 7.5 7 0 0 7 7 7 4 Sel1 repeat PA PF02225.22 CRK00489.1 - 1.8e-11 43.9 1.6 4.8e-11 42.5 1.6 1.7 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 CRK00489.1 - 0.0014 18.4 0.0 0.0045 16.7 0.0 1.9 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Pyr_redox_2 PF07992.14 CRK00489.1 - 0.057 12.6 0.1 0.1 11.8 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 CRK00498.1 - 2.6e-22 79.2 50.8 2.7e-19 69.3 41.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3464 PF11947.8 CRK00498.1 - 0.0068 16.2 0.1 0.025 14.3 0.0 1.9 2 0 0 2 2 2 1 Photosynthesis affected mutant 68 Glyco_hydro_61 PF03443.14 CRK00511.1 - 3.1e-65 220.0 0.0 5e-65 219.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Fungal_trans PF04082.18 CRK00511.1 - 8.1e-10 38.2 0.0 1.9e-09 36.9 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK00511.1 - 1.1e-05 25.5 8.9 2e-05 24.6 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Esterase PF00756.20 CRK00522.1 - 2.8e-14 53.4 0.0 3.6e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 CRK00522.1 - 1.8e-05 24.3 0.0 0.00014 21.4 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 CRK00522.1 - 0.0074 15.6 0.0 0.01 15.1 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PUMA PF15826.5 CRK00522.1 - 0.15 12.3 0.1 0.24 11.6 0.1 1.2 1 0 0 1 1 1 0 Bcl-2-binding component 3, p53 upregulated modulator of apoptosis Acetyltransf_1 PF00583.25 CRK00527.1 - 7.1e-09 35.9 0.0 9.4e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CRK00527.1 - 2.1e-07 30.9 0.0 2.9e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CRK00527.1 - 1.5e-05 25.3 0.0 2.4e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF4590 PF15257.6 CRK00527.1 - 0.024 14.5 0.0 0.041 13.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4590) Aminotran_5 PF00266.19 CRK00533.1 - 4.8e-28 98.2 0.0 1.1e-27 97.0 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V Polysacc_deac_1 PF01522.21 CRK00545.1 - 7.1e-27 93.8 0.0 9.7e-27 93.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 CRK00545.1 - 0.011 15.0 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 DUF401 PF04165.12 CRK00553.1 - 0.025 13.9 0.5 0.069 12.5 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF401) GCV_T PF01571.21 CRK00553.1 - 0.088 12.2 0.1 1.3 8.3 0.0 2.2 2 0 0 2 2 2 0 Aminomethyltransferase folate-binding domain DPM3 PF08285.11 CRK00553.1 - 0.2 11.9 1.7 1.4 9.2 0.7 2.3 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) HET PF06985.11 CRK00560.1 - 2.1e-31 109.3 0.1 6e-31 107.8 0.1 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) zf-MYND PF01753.18 CRK00567.1 - 1.7e-05 24.8 31.4 0.0018 18.3 9.3 2.7 2 0 0 2 2 2 2 MYND finger FYVE PF01363.21 CRK00567.1 - 0.0039 17.3 6.1 0.0039 17.3 6.1 2.0 2 0 0 2 2 2 1 FYVE zinc finger zf-C2H2 PF00096.26 CRK00576.1 - 6.8e-06 26.3 11.6 0.0027 18.1 1.6 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CRK00576.1 - 0.00028 21.2 3.8 0.00028 21.2 3.8 2.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 CRK00576.1 - 0.0004 21.0 11.0 0.074 13.9 2.9 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 CRK00576.1 - 1.5 8.7 5.6 2.5 8.0 0.4 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain DUF1977 PF09320.11 CRK00833.1 - 4.2e-32 110.5 0.8 4.8e-32 110.3 0.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) Frag1 PF10277.9 CRK00925.1 - 3.3e-37 128.2 4.5 4e-37 127.9 4.5 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family p450 PF00067.22 CRK00925.1 - 5.9e-12 45.1 0.0 7.8e-12 44.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DPM2 PF07297.12 CRK01007.1 - 8.8e-14 51.6 0.2 9.3e-14 51.5 0.2 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 CRK01007.1 - 0.067 13.1 0.0 0.069 13.1 0.0 1.1 1 0 0 1 1 1 0 PIG-P Importin_rep_5 PF18816.1 CRK01130.1 - 7.6e-06 26.1 2.7 7.6e-06 26.1 2.7 1.8 2 0 0 2 2 2 1 Importin repeat Dabb PF07876.12 CRK01264.1 - 6.9e-06 26.6 0.0 8e-06 26.4 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Ribosomal_S4e PF00900.20 CRK01339.1 - 2.5e-22 78.5 0.2 5.3e-22 77.5 0.1 1.6 2 0 0 2 2 2 1 Ribosomal family S4e RS4NT PF08071.12 CRK01339.1 - 5.2e-18 64.9 4.0 8.7e-18 64.2 4.0 1.4 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 CRK01339.1 - 4.7e-07 29.4 0.0 8.8e-07 28.5 0.0 1.5 1 0 0 1 1 1 1 S4 domain Actin PF00022.19 CRK01463.1 - 4e-18 65.2 0.0 5e-18 64.9 0.0 1.0 1 0 0 1 1 1 1 Actin SIR2 PF02146.17 CRK01813.1 - 5.1e-52 176.4 0.0 7.5e-52 175.8 0.0 1.3 1 0 0 1 1 1 1 Sir2 family Peptidase_S8 PF00082.22 CRK01822.1 - 1.9e-37 129.1 8.2 3.9e-37 128.1 8.2 1.4 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 CRK01822.1 - 1.5e-21 76.9 0.3 4.4e-21 75.3 0.3 1.9 1 0 0 1 1 1 1 Peptidase inhibitor I9 Beach PF02138.18 CRK01836.1 - 7.4e-120 399.5 0.0 1.3e-119 398.7 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 CRK01836.1 - 5.5e-10 39.2 0.0 1.5e-09 37.9 0.0 1.8 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 CRK01836.1 - 4.1e-09 36.8 0.0 8.2e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF4704 PF15787.5 CRK01836.1 - 0.12 11.6 0.3 0.57 9.4 0.3 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4704) EB_dh PF09459.10 CRK01845.1 - 0.058 13.3 0.0 0.062 13.3 0.0 1.1 1 0 0 1 1 1 0 Ethylbenzene dehydrogenase Rad21_Rec8_N PF04825.13 CRK01863.1 - 1.4e-29 102.5 0.0 3e-29 101.4 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 CRK01863.1 - 2e-05 23.8 0.9 0.0001 21.5 0.0 2.5 3 0 0 3 3 3 1 Conserved region of Rad21 / Rec8 like protein DUF2283 PF10049.9 CRK01863.1 - 0.033 14.4 0.4 0.087 13.1 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2283) GDI PF00996.18 CRK01872.1 - 6.2e-21 74.4 0.0 2.7e-20 72.3 0.0 1.8 1 1 0 1 1 1 1 GDP dissociation inhibitor RNase_PH PF01138.21 CRK01872.1 - 1.3e-16 61.3 0.0 1.1e-15 58.3 0.0 2.5 2 2 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CRK01872.1 - 0.0017 18.4 0.0 0.0037 17.3 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Acetyltransf_17 PF17668.1 CRK01872.1 - 0.067 14.0 0.2 0.19 12.6 0.2 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ferric_reduct PF01794.19 CRK01888.1 - 2.9e-19 69.4 3.5 2.9e-19 69.4 3.5 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 CRK01888.1 - 4.9e-15 56.0 0.0 4.4e-10 39.9 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 CRK01888.1 - 1.2e-12 47.8 0.0 3.1e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 CRK01888.1 - 0.00016 22.3 0.0 0.061 14.0 0.0 2.5 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain CDC45 PF02724.14 CRK01898.1 - 2.4 6.4 7.1 4.1 5.6 7.1 1.4 1 0 0 1 1 1 0 CDC45-like protein DUF5401 PF17380.2 CRK01905.1 - 0.17 9.9 0.3 0.25 9.4 0.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) DUF4006 PF13179.6 CRK01922.1 - 0.016 15.1 0.0 0.022 14.6 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF4006) CD34_antigen PF06365.12 CRK01922.1 - 0.02 14.5 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family EphA2_TM PF14575.6 CRK01922.1 - 0.023 15.6 0.0 0.028 15.3 0.0 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Protocadherin PF08374.11 CRK01922.1 - 0.044 13.8 0.0 0.05 13.6 0.0 1.1 1 0 0 1 1 1 0 Protocadherin DUF3169 PF11368.8 CRK01922.1 - 0.16 11.5 0.0 0.21 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Glyco_hydro_76 PF03663.14 CRK01929.1 - 2.4e-152 507.7 11.0 3.6e-152 507.1 11.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Atg29_N PF18388.1 CRK01929.1 - 4e-25 87.4 0.3 1.3e-24 85.8 0.3 2.0 1 0 0 1 1 1 1 Atg29 N-terminal domain Pkinase PF00069.25 CRK01929.1 - 3.4e-20 72.5 0.0 5.1e-10 39.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CRK01929.1 - 1.7e-07 30.8 0.0 7.8e-06 25.3 0.0 2.6 3 0 0 3 3 3 1 Protein tyrosine kinase APH PF01636.23 CRK01929.1 - 0.0013 18.8 0.0 0.0051 16.8 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CRK01929.1 - 0.015 14.7 0.0 0.12 11.7 0.0 2.2 3 0 0 3 3 3 0 Kinase-like DUF3245 PF11595.8 CRK01929.1 - 0.027 14.9 0.3 0.027 14.9 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) Glyco_hydro_88 PF07470.13 CRK01929.1 - 0.072 12.2 8.3 0.088 11.9 0.1 2.8 3 0 0 3 3 3 0 Glycosyl Hydrolase Family 88 Kdo PF06293.14 CRK01929.1 - 0.079 12.3 0.0 0.28 10.5 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family PPP4R2 PF09184.11 CRK01929.1 - 1.9 8.0 3.2 3.1 7.3 3.2 1.2 1 0 0 1 1 1 0 PPP4R2 BLOC1S3 PF15753.5 CRK01929.1 - 3.6 7.7 5.8 8.2 6.5 5.8 1.6 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 DNA_pol_phi PF04931.13 CRK01929.1 - 3.9 5.5 7.6 6.1 4.8 7.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi Fasciclin PF02469.22 CRK01948.1 - 4.6e-46 156.2 0.4 6.9e-25 87.7 0.1 2.2 2 0 0 2 2 2 2 Fasciclin domain Se-cys_synth_N PF12390.8 CRK01948.1 - 0.0092 16.2 0.5 0.03 14.5 0.5 1.9 1 0 0 1 1 1 1 Selenocysteine synthase N terminal CSTF2_hinge PF14327.6 CRK01948.1 - 0.048 14.1 3.6 1.4 9.4 0.1 3.5 3 0 0 3 3 3 0 Hinge domain of cleavage stimulation factor subunit 2 Isy1 PF06246.12 CRK01955.1 - 8e-61 205.8 0.6 9.8e-61 205.5 0.6 1.0 1 0 0 1 1 1 1 Isy1-like splicing family adh_short PF00106.25 CRK01963.1 - 5.9e-12 45.4 0.0 8.7e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK01963.1 - 1.1e-06 28.4 0.0 1.5e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK01963.1 - 3.6e-05 23.7 0.0 6.2e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF4006 PF13179.6 CRK01973.1 - 0.016 15.1 0.0 0.022 14.6 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF4006) CD34_antigen PF06365.12 CRK01973.1 - 0.02 14.5 0.0 0.03 13.9 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family EphA2_TM PF14575.6 CRK01973.1 - 0.021 15.7 0.0 0.027 15.3 0.0 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Protocadherin PF08374.11 CRK01973.1 - 0.04 13.9 0.0 0.047 13.7 0.0 1.1 1 0 0 1 1 1 0 Protocadherin DUF3169 PF11368.8 CRK01973.1 - 0.16 11.5 0.0 0.21 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Glyco_hydro_76 PF03663.14 CRK01986.1 - 2.2e-140 468.4 12.8 2.8e-140 468.0 12.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 CRK01986.1 - 0.00045 19.4 7.3 0.026 13.6 0.1 2.9 3 0 0 3 3 3 2 Glycosyl Hydrolase Family 88 Synaptobrevin PF00957.21 CRK01993.1 - 2.1e-33 113.9 1.1 2.5e-33 113.7 1.1 1.0 1 0 0 1 1 1 1 Synaptobrevin HrpB4 PF09502.10 CRK01993.1 - 0.078 12.8 0.0 0.088 12.6 0.0 1.1 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB4) AKNA PF12443.8 CRK01993.1 - 0.078 13.6 0.1 0.3 11.7 0.1 1.7 1 1 1 2 2 2 0 AT-hook-containing transcription factor Chi-conotoxin PF16981.5 CRK01993.1 - 6.9 7.0 6.2 3.7 7.8 2.5 2.3 2 1 1 3 3 3 0 chi-Conotoxin or t superfamily Fasciclin PF02469.22 CRK01998.1 - 2.7e-47 160.2 1.5 1.1e-23 83.8 0.1 2.2 2 0 0 2 2 2 2 Fasciclin domain Se-cys_synth_N PF12390.8 CRK01998.1 - 0.008 16.4 4.1 0.057 13.7 0.5 3.7 3 0 0 3 3 3 1 Selenocysteine synthase N terminal CSTF2_hinge PF14327.6 CRK01998.1 - 3.9 8.0 9.1 0.78 10.2 0.3 3.6 4 0 0 4 4 4 0 Hinge domain of cleavage stimulation factor subunit 2 Isy1 PF06246.12 CRK02002.1 - 5.8e-89 298.0 0.7 6.6e-89 297.8 0.7 1.0 1 0 0 1 1 1 1 Isy1-like splicing family EMC1_C PF07774.13 CRK02007.1 - 2.4e-73 246.4 0.0 4.9e-73 245.3 0.0 1.6 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 CRK02007.1 - 7.5e-30 104.3 17.2 9.6e-19 67.9 3.2 3.8 4 0 0 4 4 4 3 PQQ-like domain PQQ PF01011.21 CRK02007.1 - 0.023 14.6 8.9 0.62 10.1 0.1 6.5 8 0 0 8 8 8 0 PQQ enzyme repeat GATase_7 PF13537.6 CRK02007.1 - 0.044 13.7 0.1 19 5.2 0.0 2.9 2 0 0 2 2 2 0 Glutamine amidotransferase domain WSC PF01822.19 CRK02014.1 - 3.1e-44 149.1 56.1 4.4e-13 49.2 9.3 4.3 4 0 0 4 4 4 4 WSC domain Exo_endo_phos PF03372.23 CRK02025.1 - 5.4e-06 26.1 0.0 8.8e-06 25.4 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pkinase PF00069.25 CRK02031.1 - 1.3e-53 182.1 0.0 1.5e-25 90.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CRK02031.1 - 1.2e-28 100.2 0.0 4.5e-13 49.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 CRK02031.1 - 2.8e-19 69.2 0.1 1.8e-08 33.6 0.0 2.1 2 0 0 2 2 2 2 Fungal protein kinase APH PF01636.23 CRK02031.1 - 4.2e-10 39.9 0.0 0.0031 17.5 0.0 3.5 3 1 0 4 4 4 2 Phosphotransferase enzyme family zf-CCHC PF00098.23 CRK02031.1 - 7.1e-06 25.9 5.4 1.3e-05 25.0 5.4 1.4 1 0 0 1 1 1 1 Zinc knuckle Pox_ser-thr_kin PF05445.11 CRK02031.1 - 7e-05 22.0 0.8 0.27 10.2 0.1 2.1 2 0 0 2 2 2 2 Poxvirus serine/threonine protein kinase Kdo PF06293.14 CRK02031.1 - 0.00085 18.7 0.4 1.4 8.3 0.1 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Gal_GalNac_35kD PF17337.2 CRK02031.1 - 0.011 15.8 0.1 7.8 6.5 0.0 2.5 2 0 0 2 2 2 0 Galactose-inhibitable lectin 35 kDa subunit YL1_C PF08265.11 CRK02031.1 - 0.056 13.2 1.9 9.4 6.1 0.1 2.5 2 0 0 2 2 2 0 YL1 nuclear protein C-terminal domain zf-CCHC_5 PF14787.6 CRK02031.1 - 0.53 10.0 2.6 0.89 9.3 2.6 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger CNH PF00780.22 CRK02043.1 - 4.2e-66 223.4 0.0 6.3e-66 222.8 0.0 1.2 1 0 0 1 1 1 1 CNH domain Beta-lactamase PF00144.24 CRK02043.1 - 3.9e-37 128.2 1.1 9.8e-37 126.9 1.1 1.6 1 0 0 1 1 1 1 Beta-lactamase RhoGEF PF00621.20 CRK02043.1 - 7.7e-32 111.0 0.2 1.2e-31 110.4 0.2 1.3 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 CRK02043.1 - 1.3e-10 41.5 0.0 4.1e-10 39.9 0.0 1.9 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 CRK02043.1 - 0.00027 21.4 0.0 0.0045 17.5 0.0 2.6 2 0 0 2 2 2 1 PH domain PH_16 PF17838.1 CRK02043.1 - 0.079 12.8 0.1 10 6.0 0.0 2.4 2 0 0 2 2 2 0 PH domain TAL_FSA PF00923.19 CRK02048.1 - 1.3e-89 300.4 1.1 2.2e-89 299.6 1.1 1.4 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase SNase PF00565.17 CRK02048.1 - 2.1e-66 221.2 0.1 6.9e-19 68.3 0.0 5.5 5 0 0 5 5 5 5 Staphylococcal nuclease homologue Sod_Cu PF00080.20 CRK02048.1 - 1.3e-37 129.1 4.4 1.3e-37 129.1 4.4 2.2 2 0 0 2 2 2 1 Copper/zinc superoxide dismutase (SODC) TUDOR PF00567.24 CRK02048.1 - 1.2e-22 80.2 0.0 2.2e-22 79.4 0.0 1.4 1 0 0 1 1 1 1 Tudor domain SMN PF06003.12 CRK02048.1 - 0.00075 18.8 0.2 0.0032 16.8 0.1 2.0 2 0 0 2 2 2 1 Survival motor neuron protein (SMN) RNA_pol_Rpb1_3 PF04983.18 CRK02048.1 - 0.085 12.8 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 3 Amino_oxidase PF01593.24 CRK02508.1 - 1.7e-13 50.7 0.1 2.1e-13 50.4 0.1 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase WD40 PF00400.32 CRK02833.1 - 3e-08 34.2 1.8 0.0025 18.6 0.1 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK02833.1 - 5.2e-07 29.9 0.1 2.3e-06 27.8 0.1 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain DS PF01916.17 CRK02941.1 - 5.2e-40 137.5 0.0 5.7e-40 137.4 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Inhibitor_I10 PF12559.8 CRK02941.1 - 0.026 14.8 0.0 0.035 14.4 0.0 1.2 1 0 0 1 1 1 0 Serine endopeptidase inhibitors CnrY PF17524.2 CRK03065.1 - 0.02 15.1 0.3 0.039 14.2 0.3 1.4 1 0 0 1 1 1 0 Anti-sigma factor CnrY Fungal_trans_2 PF11951.8 CRK03076.1 - 6.6e-48 163.4 4.6 2e-47 161.8 4.6 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK03076.1 - 5.3e-14 52.1 22.7 9.7e-07 28.8 7.3 2.6 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4082 PF13313.6 CRK03076.1 - 0.043 13.9 0.6 10 6.2 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4082) ORC6 PF05460.13 CRK03076.1 - 0.078 12.2 10.5 0.88 8.8 1.7 2.6 3 0 0 3 3 3 0 Origin recognition complex subunit 6 (ORC6) PSI_integrin PF17205.3 CRK03076.1 - 0.3 10.9 10.3 3.1 7.6 1.6 2.9 2 0 0 2 2 2 0 Integrin plexin domain LRRNT PF01462.18 CRK03076.1 - 5.4 6.8 7.2 27 4.6 0.8 2.9 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain MFS_1 PF07690.16 CRK03084.1 - 1.5e-44 152.4 44.4 1.5e-44 152.4 44.4 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK03084.1 - 3.1e-18 65.9 11.6 3.1e-18 65.9 11.6 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 CRK03084.1 - 1.4e-06 27.1 17.2 1.4e-06 27.1 15.1 1.6 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) AMP-binding PF00501.28 CRK03091.1 - 6.1e-14 51.4 0.1 1.9e-06 26.8 0.0 2.1 1 1 1 2 2 2 2 AMP-binding enzyme Hid1 PF12722.7 CRK03099.1 - 5.3e-291 967.6 0.0 7.6e-291 967.0 0.0 1.1 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 CRK03099.1 - 1.3e-96 324.5 0.0 1.8e-96 324.0 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein NPCC PF08058.11 CRK03099.1 - 1.5e-23 83.3 0.0 3.9e-23 81.9 0.0 1.8 1 0 0 1 1 1 1 Nuclear pore complex component DUF913 PF06025.12 CRK03099.1 - 0.013 14.5 1.6 0.027 13.5 1.6 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) EHN PF06441.12 CRK03120.1 - 2.7e-26 92.1 0.5 4.9e-26 91.2 0.5 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Homeodomain PF00046.29 CRK03128.1 - 7.6e-18 64.1 3.0 1.5e-17 63.2 3.0 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CRK03128.1 - 0.0045 16.9 0.1 0.011 15.6 0.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain Fungal_trans_2 PF11951.8 CRK03136.1 - 1.4e-48 165.7 5.3 4.9e-48 163.9 5.3 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 CRK03143.1 - 1.8e-44 152.1 44.5 1.8e-44 152.1 44.5 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK03143.1 - 3.1e-18 65.9 11.6 3.1e-18 65.9 11.6 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 CRK03143.1 - 1.2e-06 27.3 17.0 1.3e-06 27.2 14.8 1.6 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) AMP-binding PF00501.28 CRK03149.1 - 1.4e-14 53.5 0.2 1.9e-06 26.8 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme NPCC PF08058.11 CRK03159.1 - 1.6e-24 86.4 0.0 2.6e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 Nuclear pore complex component Hid1 PF12722.7 CRK03174.1 - 1.8e-302 1005.5 0.0 2e-302 1005.4 0.0 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 CRK03174.1 - 7.2e-105 351.8 0.0 8.8e-105 351.5 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein DUF913 PF06025.12 CRK03174.1 - 0.017 14.1 0.7 0.033 13.2 0.7 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Sec23_trunk PF04811.15 CRK03174.1 - 0.18 11.4 0.0 0.32 10.5 0.0 1.3 1 0 0 1 1 1 0 Sec23/Sec24 trunk domain EHN PF06441.12 CRK03183.1 - 1.4e-26 93.0 0.5 2.5e-26 92.1 0.5 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Homeodomain PF00046.29 CRK03190.1 - 6.6e-18 64.3 3.0 1.3e-17 63.4 3.0 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CRK03190.1 - 0.0024 17.7 0.2 0.0098 15.8 0.1 2.0 2 0 0 2 2 2 1 Homeobox KN domain Flavodoxin_NdrI PF07972.11 CRK03198.1 - 0.037 14.2 0.2 6.6 6.9 0.0 2.1 2 0 0 2 2 2 0 NrdI Flavodoxin like 3HCDH_N PF02737.18 CRK03204.1 - 3.1e-90 300.9 10.8 4.2e-37 127.8 0.6 3.1 1 1 2 3 3 3 3 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 CRK03204.1 - 2e-32 111.6 0.0 4.3e-32 110.6 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Sacchrp_dh_NADP PF03435.18 CRK03204.1 - 5.5e-06 26.7 2.3 0.00015 22.0 0.1 2.9 2 1 1 3 3 3 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 CRK03204.1 - 0.0006 20.0 0.7 0.0067 16.6 0.1 2.5 1 1 1 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox_2 PF07992.14 CRK03204.1 - 0.013 14.8 0.0 0.027 13.7 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 CRK03204.1 - 0.015 14.8 0.8 0.25 10.9 0.4 2.7 2 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PHBC_N PF12551.8 CRK03204.1 - 0.027 14.2 7.5 1.9 8.3 0.9 2.9 2 0 0 2 2 2 0 Poly-beta-hydroxybutyrate polymerase N terminal DAO PF01266.24 CRK03204.1 - 0.03 13.9 0.0 0.043 13.4 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 CRK03204.1 - 0.033 13.5 1.1 0.37 10.1 0.3 2.5 1 1 2 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Fer4_16 PF13484.6 CRK03204.1 - 0.054 14.4 0.8 56 4.8 0.1 3.3 3 0 0 3 3 3 0 4Fe-4S double cluster binding domain F420_oxidored PF03807.17 CRK03204.1 - 0.22 12.1 4.8 0.29 11.8 0.8 3.1 3 1 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 CRK03204.1 - 0.45 10.8 0.0 0.45 10.8 0.0 3.2 3 2 2 5 5 5 0 TrkA-N domain TIMELESS PF04821.14 CRK03210.1 - 2.1e-76 256.8 0.3 7.2e-76 255.1 0.0 1.9 2 0 0 2 2 2 1 Timeless protein TIMELESS_C PF05029.13 CRK03210.1 - 2.5e-59 201.9 33.2 3.9e-38 132.0 2.6 4.8 3 2 0 4 4 4 2 Timeless protein C terminal region FANCI_S2 PF14676.6 CRK03210.1 - 0.0092 16.3 0.1 4.2 7.7 0.0 3.2 4 0 0 4 4 4 2 FANCI solenoid 2 DUF2474 PF10617.9 CRK03210.1 - 7.2 6.6 5.3 47 4.0 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2474) TIMELESS PF04821.14 CRK03220.1 - 5.1e-89 298.2 1.2 2.7e-88 295.9 0.0 2.1 2 0 0 2 2 2 1 Timeless protein Cnd1_N PF12922.7 CRK03220.1 - 0.052 13.4 0.5 10 6.0 0.0 2.6 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term Nfu_N PF08712.11 CRK03220.1 - 0.088 12.9 0.0 0.29 11.2 0.0 1.9 1 0 0 1 1 1 0 Scaffold protein Nfu/NifU N terminal FAM176 PF14851.6 CRK03220.1 - 0.18 11.4 4.0 0.17 11.6 1.7 2.2 2 0 0 2 2 2 0 FAM176 family Ctr PF04145.15 CRK03220.1 - 4.2 8.0 5.8 5.2 7.7 0.5 2.6 3 0 0 3 3 3 0 Ctr copper transporter family PDCD2_C PF04194.13 CRK03220.1 - 5.5 7.0 6.4 16 5.5 0.1 2.4 2 0 0 2 2 2 0 Programmed cell death protein 2, C-terminal putative domain HCO3_cotransp PF00955.21 CRK03227.1 - 8.9e-144 480.1 30.6 1.7e-44 152.5 4.1 4.1 2 2 2 4 4 4 4 HCO3- transporter family DUF601 PF04642.12 CRK03227.1 - 0.056 12.9 8.2 1.4 8.4 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF601 TNFR_16_TM PF18422.1 CRK03227.1 - 0.64 10.0 19.3 0.44 10.6 1.7 3.7 3 0 0 3 3 3 0 Tumor necrosis factor receptor member 16 trans-membrane domain Peptidase_M41 PF01434.18 CRK03236.1 - 7.3e-67 224.9 0.0 1.4e-66 224.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 CRK03236.1 - 3.6e-42 143.9 0.0 7.4e-42 142.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) HCO3_cotransp PF00955.21 CRK03236.1 - 8.1e-10 38.1 0.1 1.3e-09 37.4 0.1 1.2 1 0 0 1 1 1 1 HCO3- transporter family AAA_lid_3 PF17862.1 CRK03236.1 - 1e-09 38.0 0.0 2.6e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 CRK03236.1 - 1.8e-07 31.5 0.2 3.9e-07 30.4 0.2 1.6 1 0 0 1 1 1 1 FtsH Extracellular AAA_5 PF07728.14 CRK03236.1 - 0.0014 18.6 0.0 0.0051 16.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CRK03236.1 - 0.0022 18.4 0.9 0.13 12.7 0.2 3.1 2 1 0 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 CRK03236.1 - 0.0064 16.6 0.0 0.059 13.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 CRK03236.1 - 0.011 15.5 0.0 0.029 14.1 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 CRK03236.1 - 0.012 14.8 0.1 0.022 14.0 0.1 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_22 PF13401.6 CRK03236.1 - 0.022 15.0 0.1 1.2 9.4 0.1 2.6 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 CRK03236.1 - 0.087 12.5 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_pol_Rpc4 PF05132.14 CRK03236.1 - 0.16 12.4 7.9 0.8 10.1 7.9 1.9 1 1 0 1 1 1 0 RNA polymerase III RPC4 Peptidase_M41 PF01434.18 CRK03241.1 - 3.2e-67 226.1 0.0 5.9e-67 225.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA_lid_3 PF17862.1 CRK03241.1 - 6.4e-10 38.7 0.0 1.4e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 CRK03241.1 - 2.6e-06 27.9 0.0 6.7e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF676 PF05057.14 CRK03248.1 - 5.8e-07 29.2 0.0 1.4e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 CRK03248.1 - 2e-05 24.4 0.1 0.00014 21.6 0.1 2.1 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 CRK03248.1 - 0.00029 21.5 2.8 0.00029 21.5 2.8 2.2 1 1 1 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CRK03248.1 - 0.003 16.9 0.0 0.0087 15.3 0.0 1.7 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Lipase_3 PF01764.25 CRK03248.1 - 0.0033 17.3 0.0 0.0058 16.5 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_3 PF07859.13 CRK03248.1 - 0.14 12.0 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.20 CRK03248.1 - 0.26 11.4 0.0 0.26 11.4 0.0 2.5 2 1 0 2 2 2 0 Thioesterase domain UPF0227 PF05728.12 CRK03248.1 - 0.31 11.0 2.0 0.33 10.9 0.1 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Rox3 PF08633.10 CRK03253.1 - 1.9e-51 175.3 1.3 2.3e-51 175.0 0.4 1.6 2 0 0 2 2 2 1 Rox3 mediator complex subunit TSGP1 PF07771.11 CRK03253.1 - 3.4 7.8 7.5 1.6 8.9 0.9 2.5 2 0 0 2 2 2 0 Tick salivary peptide group 1 MCM PF00493.23 CRK03255.1 - 5.4e-105 349.4 0.2 1.3e-104 348.2 0.1 1.7 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 CRK03255.1 - 2.5e-36 124.3 0.2 4.6e-36 123.4 0.2 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CRK03255.1 - 2.3e-27 95.2 1.2 5.8e-27 94.0 1.2 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CRK03255.1 - 3.2e-16 59.8 1.7 8.2e-16 58.5 1.7 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 CRK03255.1 - 1.6e-06 27.7 0.0 0.00021 20.8 0.0 2.4 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CRK03255.1 - 2e-05 24.6 0.0 4.9e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 CRK03255.1 - 0.0004 20.3 0.0 0.0018 18.1 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CRK03255.1 - 0.058 13.1 0.0 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.29 CRK03255.1 - 0.091 13.2 0.0 0.3 11.5 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Vps54 PF07928.12 CRK03258.1 - 5.8e-52 175.7 1.8 1.3e-51 174.5 0.0 2.6 3 0 0 3 3 3 1 Vps54-like protein Vps54_N PF10475.9 CRK03258.1 - 8.1e-08 31.9 0.6 2.1e-07 30.5 0.6 1.6 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex DUF5364 PF17322.2 CRK03258.1 - 0.00023 21.6 0.6 0.0021 18.4 0.2 2.6 2 0 0 2 2 2 1 Family of unknown function (DUF5364) FerA PF08165.11 CRK03258.1 - 0.0054 16.7 1.1 0.026 14.5 1.1 2.3 1 0 0 1 1 1 1 FerA (NUC095) domain FliJ PF02050.16 CRK03258.1 - 0.054 13.7 0.2 0.22 11.8 0.2 2.0 1 0 0 1 1 1 0 Flagellar FliJ protein Sec8_exocyst PF04048.14 CRK03258.1 - 0.11 12.3 1.4 0.79 9.6 0.2 2.8 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain COG2 PF06148.11 CRK03258.1 - 0.13 12.4 1.2 0.5 10.5 0.4 2.4 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 ANAPC8 PF04049.13 CRK03269.1 - 1.1e-24 87.0 0.6 2.7e-24 85.8 0.1 1.8 3 0 0 3 3 3 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_8 PF13181.6 CRK03269.1 - 2.7e-11 42.8 2.5 0.00041 20.3 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 CRK03269.1 - 8.7e-06 25.9 0.5 0.21 11.9 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 CRK03269.1 - 0.00033 20.4 0.5 1.2 9.1 0.0 3.8 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 CRK03269.1 - 0.001 19.0 5.8 4 7.8 0.2 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 CRK03269.1 - 0.0014 19.1 6.4 0.059 14.0 0.1 4.3 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 CRK03269.1 - 0.011 16.4 2.4 3 8.6 1.0 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 CRK03269.1 - 0.016 15.7 5.3 14 6.3 0.4 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 CRK03269.1 - 0.035 14.3 8.6 0.54 10.5 0.2 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 CRK03269.1 - 0.2 11.6 3.9 4.5 7.3 0.0 3.6 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF4398 PF14346.6 CRK03269.1 - 5.9 7.6 13.1 0.92 10.2 7.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) polyprenyl_synt PF00348.17 CRK03273.1 - 9e-73 244.5 0.0 2.5e-46 157.8 0.1 2.0 1 1 1 2 2 2 2 Polyprenyl synthetase DAHP_synth_1 PF00793.20 CRK03372.1 - 2.8e-103 344.5 0.1 3.4e-103 344.3 0.1 1.0 1 0 0 1 1 1 1 DAHP synthetase I family YIEGIA PF14045.6 CRK03372.1 - 0.055 12.3 0.1 0.11 11.3 0.1 1.4 1 0 0 1 1 1 0 YIEGIA protein AMP-binding PF00501.28 CRK03669.1 - 1.8e-08 33.5 0.0 1.8e-08 33.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Aldedh PF00171.22 CRK03744.1 - 2e-37 128.8 0.0 2.3e-37 128.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family HLH PF00010.26 CRK04020.1 - 2e-10 40.4 0.5 2.9e-10 40.0 0.5 1.2 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain NIF PF03031.18 CRK04117.1 - 4.2e-09 36.4 0.0 6e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF3140 PF11338.8 CRK04211.1 - 1.9e-33 114.8 2.1 2.3e-33 114.5 2.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3140) Lipocalin_2 PF08212.12 CRK04217.1 - 3.7e-20 72.4 0.0 4.3e-20 72.1 0.0 1.1 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.23 CRK04217.1 - 0.0002 21.6 0.0 0.0006 20.0 0.0 1.7 1 1 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family EthD PF07110.11 CRK04223.1 - 0.0013 19.9 0.2 0.06 14.5 0.0 2.3 2 0 0 2 2 2 1 EthD domain DUF4286 PF14114.6 CRK04223.1 - 0.037 14.5 0.0 4.2 7.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4286) HhH-GPD PF00730.25 CRK04227.1 - 4.7e-08 33.4 0.0 9.5e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 CRK04227.1 - 0.048 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif Glyco_trans_2_3 PF13632.6 CRK04233.1 - 2.7e-47 161.2 3.0 2.7e-47 161.2 3.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 CRK04233.1 - 2.9e-06 27.2 0.0 4.2e-05 23.4 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 CRK04233.1 - 0.00054 19.5 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 CRK04233.1 - 0.0022 17.9 0.0 0.0037 17.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Fungal_trans_2 PF11951.8 CRK04244.1 - 1.3e-15 57.2 3.7 2.6e-15 56.1 3.7 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK04250.1 - 0.011 15.8 0.4 0.02 15.0 0.4 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.21 CRK04257.1 - 1.1e-43 149.6 0.0 1.3e-43 149.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Lactamase_B_4 PF13691.6 CRK04257.1 - 0.017 14.8 0.0 0.068 12.9 0.0 1.9 2 0 0 2 2 2 0 tRNase Z endonuclease ADH_N PF08240.12 CRK04263.1 - 3.5e-29 100.9 0.6 6.4e-29 100.0 0.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CRK04263.1 - 1.2e-10 41.5 0.0 1.9e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 CRK04263.1 - 0.0004 19.9 0.9 0.17 11.3 0.2 2.3 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus ABC_tran PF00005.27 CRK04270.1 - 8e-32 110.6 0.0 1.9e-31 109.4 0.0 1.7 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 CRK04270.1 - 7.9e-20 71.6 3.7 7.9e-20 71.6 3.7 3.0 4 0 0 4 4 4 2 ABC transporter transmembrane region SMC_N PF02463.19 CRK04270.1 - 1.2e-05 24.9 0.2 0.0014 18.1 0.2 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 CRK04270.1 - 0.0057 16.8 0.3 0.016 15.4 0.0 1.8 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_16 PF13191.6 CRK04270.1 - 0.0057 17.1 0.2 0.044 14.2 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 CRK04270.1 - 0.0093 15.8 0.1 3.4 7.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 CRK04270.1 - 0.016 15.3 0.0 0.043 13.9 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase IstB_IS21 PF01695.17 CRK04270.1 - 0.016 14.9 0.1 0.044 13.5 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF4337 PF14235.6 CRK04270.1 - 0.13 12.4 1.8 0.28 11.3 1.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) AAA_23 PF13476.6 CRK04270.1 - 0.13 12.7 0.9 0.28 11.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 CRK04270.1 - 0.17 11.7 0.0 0.37 10.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SecY PF00344.20 CRK04276.1 - 5e-71 239.5 7.7 6.5e-71 239.1 7.7 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 CRK04276.1 - 4.8e-17 61.5 0.3 1.3e-16 60.1 0.3 1.9 1 0 0 1 1 1 1 Plug domain of Sec61p QCR10 PF09796.9 CRK04276.1 - 0.043 13.9 1.7 6.7 6.9 0.0 3.5 3 0 0 3 3 3 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) DUF3817 PF12823.7 CRK04276.1 - 0.072 13.9 0.7 1.7 9.5 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3817) IPPT PF01715.17 CRK04282.1 - 1.6e-57 195.0 0.0 3e-57 194.1 0.0 1.4 1 0 0 1 1 1 1 IPP transferase zf-met PF12874.7 CRK04282.1 - 1.2e-07 31.9 3.8 2.5e-07 30.9 3.8 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CRK04282.1 - 8.4e-06 25.9 3.7 8.4e-06 25.9 3.7 1.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding IPT PF01745.16 CRK04282.1 - 0.00013 21.4 0.0 0.00064 19.2 0.0 1.9 2 0 0 2 2 2 1 Isopentenyl transferase zf-C2H2_2 PF12756.7 CRK04282.1 - 0.0003 21.1 1.1 0.00057 20.2 1.1 1.3 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) AAA_33 PF13671.6 CRK04282.1 - 0.00041 20.5 1.0 0.0098 16.1 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 CRK04282.1 - 0.0074 16.7 0.2 0.036 14.5 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 CRK04282.1 - 0.012 15.4 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.6 CRK04282.1 - 0.023 15.0 0.1 0.11 12.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain CTU2 PF10288.9 CRK04282.1 - 0.026 14.8 0.3 0.047 13.9 0.3 1.4 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 Hpr_kinase_C PF07475.12 CRK04282.1 - 0.066 12.7 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain PhoH PF02562.16 CRK04282.1 - 0.12 11.9 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein zf-C2H2_4 PF13894.6 CRK04282.1 - 1.5 9.9 4.4 0.67 10.9 1.8 1.9 2 0 0 2 2 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 CRK04282.1 - 4.8 7.8 5.4 11 6.8 5.4 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type Fungal_trans PF04082.18 CRK04286.1 - 6.4e-21 74.6 0.5 9.9e-21 74.0 0.1 1.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK04286.1 - 4.5e-09 36.3 8.6 7.1e-09 35.7 8.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF917 PF06032.12 CRK04292.1 - 1.6e-105 352.8 1.2 1.6e-105 352.8 1.2 2.0 3 0 0 3 3 3 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.18 CRK04292.1 - 1e-27 97.1 9.3 1.4e-22 80.3 0.9 3.4 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 CRK04292.1 - 1.3e-21 77.1 4.5 9e-20 71.1 0.0 3.7 4 1 0 4 4 4 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.6 CRK04292.1 - 1.4e-05 23.9 2.7 0.073 11.6 0.3 3.1 3 0 0 3 3 3 2 MutL protein StbA PF06406.11 CRK04292.1 - 0.077 12.2 0.1 4.3 6.5 0.1 2.5 1 1 0 2 2 2 0 StbA protein BcrAD_BadFG PF01869.20 CRK04292.1 - 0.19 11.2 3.3 0.64 9.5 0.0 3.1 4 0 0 4 4 4 0 BadF/BadG/BcrA/BcrD ATPase family Fungal_trans_2 PF11951.8 CRK04297.1 - 1.5e-21 76.7 0.2 2.4e-21 76.0 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK04297.1 - 2.8e-07 30.5 8.8 5.6e-07 29.6 8.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RibD_C PF01872.17 CRK04306.1 - 2.7e-18 66.6 0.0 2e-17 63.7 0.0 1.9 1 1 0 1 1 1 1 RibD C-terminal domain DHFR_1 PF00186.19 CRK04306.1 - 0.0002 21.1 0.0 0.00022 20.9 0.0 1.2 1 0 0 1 1 1 1 Dihydrofolate reductase NAD_binding_10 PF13460.6 CRK04310.1 - 2.3e-08 34.2 0.1 5.3e-08 33.0 0.1 1.6 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 CRK04310.1 - 2.3e-05 24.1 0.0 0.12 12.0 0.0 2.2 2 0 0 2 2 2 2 NmrA-like family Epimerase PF01370.21 CRK04310.1 - 0.00022 20.8 0.1 0.086 12.3 0.0 2.9 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family Aldo_ket_red PF00248.21 CRK04314.1 - 4.6e-42 144.2 0.0 9.1e-42 143.2 0.0 1.4 1 1 0 1 1 1 1 Aldo/keto reductase family GMC_oxred_N PF00732.19 CRK04324.1 - 2.2e-57 194.7 0.0 2.9e-57 194.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CRK04324.1 - 1.7e-39 135.6 0.2 3.1e-39 134.8 0.2 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 CRK04324.1 - 8.8e-08 31.6 0.9 0.0049 16.0 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 CRK04324.1 - 3.4e-06 26.9 2.8 1.1e-05 25.2 2.0 2.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 CRK04324.1 - 0.00011 21.3 0.0 0.00019 20.6 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 CRK04324.1 - 0.00037 19.8 0.0 0.005 16.1 0.0 2.2 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 CRK04324.1 - 0.00072 18.9 0.0 0.0013 18.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CRK04324.1 - 0.0014 18.8 0.2 0.0046 17.2 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 CRK04324.1 - 0.0016 17.8 0.0 0.029 13.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CRK04324.1 - 0.0099 15.9 0.2 0.046 13.7 0.1 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.14 CRK04324.1 - 0.056 12.2 0.1 0.09 11.5 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Peptidase_C4 PF00863.19 CRK04324.1 - 0.17 11.2 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 Peptidase family C4 Oxidored_FMN PF00724.20 CRK04334.1 - 5.9e-54 183.6 0.0 7.8e-54 183.2 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family GFO_IDH_MocA PF01408.22 CRK04334.1 - 1.1e-17 65.0 0.0 2.4e-17 63.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GMC_oxred_C PF05199.13 CRK04339.1 - 2.9e-39 134.8 0.1 6.5e-39 133.7 0.1 1.6 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 CRK04339.1 - 4.1e-35 121.6 0.0 5.8e-35 121.1 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 CRK04339.1 - 0.00074 18.7 0.0 0.0013 17.9 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 CRK04339.1 - 0.00079 18.7 0.0 0.016 14.5 0.0 2.3 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 CRK04339.1 - 0.0036 16.9 2.2 0.012 15.2 2.2 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CRK04339.1 - 0.0049 16.1 0.0 0.0071 15.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CRK04339.1 - 0.0069 16.6 0.2 0.024 14.9 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CRK04339.1 - 0.019 14.0 0.2 0.42 9.6 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.6 CRK04339.1 - 0.026 14.5 1.4 0.09 12.8 0.1 2.3 2 1 1 3 3 3 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 CRK04339.1 - 0.17 11.1 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 CRK04349.1 - 9.6e-13 47.8 23.7 1.2e-06 27.7 8.1 2.9 3 0 0 3 3 3 2 Major Facilitator Superfamily MASE2 PF05230.11 CRK04349.1 - 0.089 12.9 4.1 2.3 8.3 0.1 2.8 2 1 0 2 2 2 0 MASE2 domain Chromo PF00385.24 CRK04362.1 - 2e-05 24.4 4.2 0.00087 19.2 2.2 2.3 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain ABC2_membrane PF01061.24 CRK04377.1 - 6.7e-76 254.4 38.4 6.7e-43 146.6 15.9 2.4 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 CRK04377.1 - 2e-40 138.5 0.1 5e-23 82.1 0.1 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 CRK04377.1 - 3e-20 71.9 3.9 4.4e-19 68.2 0.0 3.4 3 0 0 3 3 2 1 CDR ABC transporter ABC2_membrane_3 PF12698.7 CRK04377.1 - 2.6e-06 26.8 28.8 2e-05 23.9 15.0 2.5 2 0 0 2 2 2 2 ABC-2 family transporter protein SMC_N PF02463.19 CRK04377.1 - 8.5e-05 22.1 0.0 0.22 10.9 0.0 3.4 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CRK04377.1 - 0.00013 21.9 0.0 0.15 11.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 CRK04377.1 - 0.00016 22.1 0.1 0.0085 16.5 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 CRK04377.1 - 0.00022 21.2 0.2 0.00085 19.3 0.1 1.9 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 CRK04377.1 - 0.0079 16.7 0.1 2.9 8.4 0.0 3.2 3 0 0 3 3 2 1 AAA domain cobW PF02492.19 CRK04377.1 - 0.02 14.5 0.1 0.69 9.5 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 CRK04377.1 - 0.025 14.7 0.2 0.17 12.0 0.1 2.6 3 1 0 3 3 2 0 AAA domain AAA_22 PF13401.6 CRK04377.1 - 0.026 14.8 0.1 0.65 10.3 0.1 2.9 2 1 1 3 3 3 0 AAA domain AAA_30 PF13604.6 CRK04377.1 - 0.05 13.3 0.0 0.61 9.8 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 CRK04377.1 - 0.056 13.2 0.1 0.056 13.2 0.1 2.4 3 0 0 3 3 3 0 P-loop containing region of AAA domain NACHT PF05729.12 CRK04377.1 - 0.065 13.1 0.2 1.3 9.0 0.2 2.4 2 0 0 2 2 2 0 NACHT domain AAA PF00004.29 CRK04377.1 - 0.068 13.6 0.0 18 5.8 0.0 3.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 CRK04377.1 - 0.073 12.6 0.1 0.16 11.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 CRK04377.1 - 0.076 12.7 0.1 0.52 10.0 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein PduV-EutP PF10662.9 CRK04377.1 - 0.093 12.5 0.1 2 8.1 0.1 2.5 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.6 CRK04377.1 - 0.12 12.6 0.0 0.41 10.9 0.1 1.9 2 0 0 2 2 1 0 AAA domain TsaE PF02367.17 CRK04377.1 - 0.14 12.2 0.1 0.32 11.0 0.1 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MMR_HSR1 PF01926.23 CRK04377.1 - 0.15 12.1 0.1 5.7 7.1 0.1 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase ABC2_membrane_2 PF12679.7 CRK04377.1 - 3.4 6.9 9.7 1.1 8.5 5.9 1.9 1 1 0 2 2 2 0 ABC-2 family transporter protein MFS_1 PF07690.16 CRK04390.1 - 2.1e-34 119.0 29.4 6.1e-34 117.5 29.1 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily MASE2 PF05230.11 CRK04390.1 - 0.21 11.7 8.6 1 9.5 1.9 2.9 2 1 0 2 2 2 0 MASE2 domain Chromo PF00385.24 CRK04403.1 - 1e-06 28.5 4.5 4.7e-05 23.2 2.5 2.3 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Fungal_trans PF04082.18 CRK04425.1 - 2.1e-10 40.1 0.3 2.9e-10 39.6 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain ABC2_membrane PF01061.24 CRK04433.1 - 2.4e-43 148.0 17.3 3.1e-43 147.6 17.3 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 CRK04433.1 - 4.1e-06 27.3 0.0 6.8e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter PDR_CDR PF06422.12 CRK04433.1 - 0.00027 20.8 0.0 0.00027 20.8 0.0 2.9 3 1 1 4 4 4 1 CDR ABC transporter ABC2_membrane_3 PF12698.7 CRK04433.1 - 0.00044 19.5 14.5 0.00044 19.5 14.5 1.6 2 0 0 2 2 2 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 CRK04433.1 - 0.28 10.4 7.1 0.45 9.7 7.1 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF4305 PF14146.6 CRK04433.1 - 1.8 8.9 5.6 1.7 8.9 3.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4305) TPR_2 PF07719.17 CRK04442.1 - 0.00049 20.0 3.6 0.05 13.7 0.8 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 CRK04442.1 - 0.13 12.2 0.8 0.36 10.7 0.2 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Sugar_tr PF00083.24 CRK04471.1 - 6.1e-94 315.4 23.9 7e-94 315.2 23.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK04471.1 - 2.8e-31 108.7 29.1 6.2e-31 107.6 26.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CRK04471.1 - 1.2e-05 23.9 17.0 3.6e-05 22.4 3.3 2.4 2 1 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) CFEM PF05730.11 CRK04481.1 - 8.8e-12 45.0 6.6 1.3e-11 44.4 6.6 1.3 1 0 0 1 1 1 1 CFEM domain Dicistro_VP4 PF11492.8 CRK04481.1 - 0.014 15.4 1.9 0.16 12.0 0.8 2.6 2 0 0 2 2 2 0 Cricket paralysis virus, VP4 p450 PF00067.22 CRK04489.1 - 2.8e-29 102.2 0.0 5.6e-29 101.2 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Velvet PF11754.8 CRK04498.1 - 1.1e-36 127.0 6.9 2.8e-27 96.3 0.1 2.9 1 1 2 3 3 3 2 Velvet factor Hira PF07569.11 CRK04517.1 - 6.1e-31 107.9 0.2 8.4e-31 107.4 0.2 1.2 1 0 0 1 1 1 1 TUP1-like enhancer of split CoA_binding PF02629.19 CRK04625.1 - 2.2e-27 95.6 1.2 2.2e-27 95.6 1.2 2.1 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 CRK04625.1 - 8.1e-24 84.2 0.4 1.3e-23 83.5 0.4 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 CRK04625.1 - 2.5e-10 40.3 0.1 4.4e-10 39.5 0.1 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 CRK04625.1 - 8.7e-05 23.0 0.1 0.00034 21.1 0.0 2.0 3 0 0 3 3 3 1 CoA binding domain UQ_con PF00179.26 CRK04635.1 - 3.9e-38 130.3 0.0 5.1e-38 129.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.10 CRK04635.1 - 1.4e-05 24.8 0.2 3.4e-05 23.6 0.1 1.7 2 0 0 2 2 2 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.6 CRK04635.1 - 0.0005 19.8 0.0 0.00076 19.2 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 CRK04635.1 - 0.042 13.7 0.0 0.082 12.8 0.0 1.5 1 0 0 1 1 1 0 UEV domain Nrap_D4 PF17405.2 CRK05027.1 - 2.2e-19 69.7 0.1 3.9e-19 68.9 0.0 1.4 2 0 0 2 2 2 1 Nrap protein nucleotidyltransferase domain 4 KH_8 PF17903.1 CRK05027.1 - 0.057 13.5 0.0 0.08 13.0 0.0 1.2 1 0 0 1 1 1 0 Krr1 KH1 domain PTPlike_phytase PF14566.6 CRK05027.1 - 0.09 12.9 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 Inositol hexakisphosphate Phe_hydrox_dim PF07976.12 CRK05087.1 - 7e-19 68.5 0.0 7.4e-19 68.4 0.0 1.0 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Erv26 PF04148.13 CRK05120.1 - 2.3e-19 70.0 0.7 2.5e-19 69.9 0.7 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 RRM_1 PF00076.22 CRK05146.1 - 7.7e-06 25.6 0.0 1.6e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) XRN_M PF17846.1 CRK05146.1 - 0.02 13.9 0.8 0.023 13.7 0.8 1.1 1 0 0 1 1 1 0 Xrn1 helical domain RRM_7 PF16367.5 CRK05146.1 - 0.03 14.4 0.0 0.067 13.3 0.0 1.7 1 1 1 2 2 2 0 RNA recognition motif Ada3 PF10198.9 CRK05339.1 - 5.1e-57 191.7 0.9 5.9e-57 191.5 0.9 1.0 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 YlqD PF11068.8 CRK05339.1 - 0.055 13.8 0.2 0.13 12.6 0.1 1.6 2 0 0 2 2 2 0 YlqD protein DUF4136 PF13590.6 CRK05339.1 - 0.1 13.2 0.3 10 6.7 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4136) DdrB PF12747.7 CRK05348.1 - 0.097 12.5 2.7 0.33 10.8 0.6 2.0 1 1 1 2 2 2 0 DdrB-like protein XRCC4 PF06632.12 CRK05348.1 - 1.5 7.6 13.3 1.7 7.4 13.3 1.0 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 RNA_polI_A34 PF08208.11 CRK05348.1 - 5.1 7.1 20.9 6.3 6.8 20.9 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 CZB PF13682.6 CRK05455.1 - 0.067 13.6 0.2 0.14 12.6 0.2 1.5 1 0 0 1 1 1 0 Chemoreceptor zinc-binding domain APH PF01636.23 CRK05471.1 - 1e-14 55.0 0.0 6.9e-14 52.4 0.0 2.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.11 CRK05471.1 - 0.00039 19.4 0.0 0.00092 18.2 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 CRK05471.1 - 0.001 18.7 0.0 0.0018 17.9 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase R2K_3 PF14243.6 CRK05471.1 - 0.028 14.4 0.0 0.051 13.6 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 3 EcKinase PF02958.20 CRK05471.1 - 0.035 13.4 0.0 0.075 12.3 0.0 1.5 1 0 0 1 1 1 0 Ecdysteroid kinase TPR_12 PF13424.6 CRK05475.1 - 8.5e-05 22.8 0.0 0.00016 21.9 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 CRK05475.1 - 0.00077 19.2 1.6 0.094 12.6 0.9 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TFIID-18kDa PF02269.16 CRK05494.1 - 2.3e-16 59.6 0.0 3.2e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 CRK05494.1 - 0.053 13.5 0.0 0.087 12.9 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated CENP-S PF15630.6 CRK05494.1 - 0.082 13.3 0.0 0.14 12.6 0.0 1.3 1 0 0 1 1 1 0 CENP-S protein DUF1242 PF06842.12 CRK05501.1 - 1.8e-14 53.2 0.2 3.5e-14 52.3 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) Tcp11 PF05794.13 CRK05508.1 - 6e-109 365.1 0.0 9e-109 364.5 0.0 1.3 1 0 0 1 1 1 1 T-complex protein 11 CDC45 PF02724.14 CRK05515.1 - 0.011 14.1 2.6 0.014 13.7 2.6 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 CRK05515.1 - 0.05 13.0 3.7 0.072 12.5 3.7 1.1 1 0 0 1 1 1 0 SDA1 F-box-like PF12937.7 CRK05515.1 - 0.085 12.8 0.7 0.31 10.9 0.7 2.1 1 1 0 1 1 1 0 F-box-like BUD22 PF09073.10 CRK05515.1 - 0.22 10.8 6.4 0.31 10.3 6.4 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 CRK05515.1 - 2.7 6.1 6.8 3.8 5.6 6.8 1.1 1 0 0 1 1 1 0 Nop14-like family Glyco_hydro_18 PF00704.28 CRK05520.1 - 8.5e-44 150.5 0.4 1.5e-43 149.7 0.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.20 CRK05520.1 - 1.1e-13 51.0 0.0 0.00055 19.9 0.0 4.2 4 0 0 4 4 4 3 LysM domain Chitin_bind_1 PF00187.19 CRK05520.1 - 5.5e-06 26.8 8.8 5.5e-06 26.8 8.8 3.0 2 0 0 2 2 2 1 Chitin recognition protein LysM PF01476.20 CRK05533.1 - 0.00014 21.8 0.2 29 4.9 0.0 6.2 7 0 0 7 7 7 1 LysM domain CcmH PF03918.14 CRK05533.1 - 0.00063 19.1 0.0 3.2 7.1 0.0 3.9 5 0 0 5 5 5 2 Cytochrome C biogenesis protein HSDR_N_2 PF13588.6 CRK05533.1 - 0.0021 18.1 0.7 8.6 6.4 0.0 4.1 5 0 0 5 5 5 2 Type I restriction enzyme R protein N terminus (HSDR_N) CarbpepA_inh PF02977.15 CRK05533.1 - 0.48 10.3 10.8 15 5.5 0.1 5.6 5 0 0 5 5 5 0 Carboxypeptidase A inhibitor Adenyl_transf PF04439.12 CRK05533.1 - 0.79 8.8 2.6 20 4.2 0.0 3.4 5 0 0 5 5 5 0 Streptomycin adenylyltransferase K_channel_TID PF07941.11 CRK05538.1 - 0.28 11.7 11.3 0.16 12.4 5.9 2.4 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Glyco_hydro_38N PF01074.22 CRK05543.1 - 4.1e-80 269.2 0.3 6.1e-80 268.7 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 CRK05543.1 - 1.7e-57 194.9 0.3 2.7e-57 194.3 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 CRK05543.1 - 1.8e-25 88.9 0.0 4.3e-25 87.7 0.0 1.7 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 CRK05543.1 - 1.9e-09 37.5 0.0 7e-09 35.7 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Sugar_tr PF00083.24 CRK05561.1 - 2.6e-65 221.0 21.5 3.6e-65 220.6 21.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Glyco_hydro_38C PF07748.13 CRK05561.1 - 1.4e-38 133.1 0.7 1.6e-37 129.7 0.7 2.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Glyco_hydro_38N PF01074.22 CRK05561.1 - 3.2e-28 98.9 0.6 3.6e-25 88.9 0.6 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 38 N-terminal domain MFS_1 PF07690.16 CRK05561.1 - 2.2e-19 69.6 23.5 3.3e-19 69.0 23.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Alpha-mann_mid PF09261.11 CRK05561.1 - 1.3e-06 28.5 0.1 4.2e-06 26.8 0.1 1.9 1 0 0 1 1 1 1 Alpha mannosidase middle domain MFS_1_like PF12832.7 CRK05561.1 - 0.0035 16.3 6.7 0.0035 16.3 6.7 2.3 2 1 0 2 2 2 1 MFS_1 like family Glyco_hydro38C2 PF17677.1 CRK05561.1 - 0.028 14.5 0.0 0.072 13.2 0.0 1.7 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Tetraspanin PF00335.20 CRK05561.1 - 0.038 13.7 0.2 0.038 13.7 0.2 2.0 2 0 0 2 2 2 0 Tetraspanin family NPP1 PF05630.11 CRK05568.1 - 4e-53 180.5 0.0 4.9e-53 180.2 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Ferric_reduct PF01794.19 CRK05571.1 - 1.2e-18 67.5 14.9 1.2e-18 67.5 14.9 3.0 3 0 0 3 3 3 1 Ferric reductase like transmembrane component Ank_4 PF13637.6 CRK05571.1 - 1.1e-05 25.9 0.0 0.25 12.0 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CRK05571.1 - 2.2e-05 25.0 0.0 0.082 13.5 0.0 3.5 2 1 1 3 3 3 1 Ankyrin repeats (3 copies) NAD_binding_6 PF08030.12 CRK05571.1 - 0.00024 21.2 0.4 0.33 11.1 0.0 3.1 2 1 0 3 3 3 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 CRK05571.1 - 0.00055 20.5 0.0 0.0017 19.0 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_8 PF08022.12 CRK05571.1 - 0.0014 18.7 0.0 0.0065 16.5 0.0 2.1 2 0 0 2 2 2 1 FAD-binding domain Ank_3 PF13606.6 CRK05571.1 - 0.0015 18.9 0.1 1.4 9.7 0.0 4.0 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 CRK05571.1 - 0.0048 17.3 0.1 2.8 8.5 0.0 4.1 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 CRK05571.1 - 0.04 14.2 0.1 1.4 9.3 0.0 3.4 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Uds1 PF15456.6 CRK05575.1 - 1.2e-23 83.8 1.8 1.2e-23 83.8 1.8 9.4 4 3 5 9 9 9 4 Up-regulated During Septation betaPIX_CC PF16523.5 CRK05575.1 - 0.01 15.6 3.3 0.01 15.6 3.3 5.6 5 1 1 6 6 6 0 betaPIX coiled coil CENP-F_C_Rb_bdg PF10490.9 CRK05575.1 - 0.039 13.4 0.0 0.09 12.2 0.0 1.6 1 0 0 1 1 1 0 Rb-binding domain of kinetochore protein Cenp-F/LEK1 DUF1751 PF08551.10 CRK05581.1 - 9.1e-05 23.0 0.5 0.00017 22.1 0.5 1.5 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 CRK05581.1 - 0.00054 20.0 4.0 0.0014 18.7 4.0 1.7 1 1 0 1 1 1 1 Rhomboid family DER1 PF04511.15 CRK05581.1 - 0.16 11.9 5.6 0.14 12.1 4.2 1.5 2 0 0 2 2 2 0 Der1-like family Prenyltransf PF01255.19 CRK05587.1 - 1.1e-80 270.4 0.0 1.7e-80 269.7 0.0 1.3 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase PHD PF00628.29 CRK05592.1 - 1.5e-06 28.0 7.6 2.4e-06 27.3 7.6 1.3 1 0 0 1 1 1 1 PHD-finger DUF3570 PF12094.8 CRK05592.1 - 0.32 9.8 2.6 0.48 9.2 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3570) zf-HC5HC2H PF13771.6 CRK05592.1 - 1.1 9.5 4.4 3.2 8.1 4.5 1.7 1 1 0 1 1 1 0 PHD-like zinc-binding domain LRR_4 PF12799.7 CRK05602.1 - 0.11 12.9 4.1 0.43 11.1 0.0 3.8 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) MARVEL PF01284.23 CRK05610.1 - 2e-05 24.7 7.3 2e-05 24.7 7.3 2.3 3 0 0 3 3 3 1 Membrane-associating domain GRAB PF10375.9 CRK05619.1 - 3.1e-09 36.4 1.9 5.8e-09 35.5 0.1 2.4 3 0 0 3 3 3 1 GRIP-related Arf-binding domain FPP PF05911.11 CRK05619.1 - 4e-05 22.0 14.4 4e-05 22.0 14.4 2.1 1 1 1 2 2 2 1 Filament-like plant protein, long coiled-coil Spc7 PF08317.11 CRK05619.1 - 6.2e-05 22.0 52.9 0.0001 21.3 25.2 2.6 1 1 1 2 2 2 2 Spc7 kinetochore protein Filament PF00038.21 CRK05619.1 - 7e-05 22.6 49.4 0.12 11.9 6.7 3.2 1 1 2 3 3 3 3 Intermediate filament protein ABC_tran_CTD PF16326.5 CRK05619.1 - 0.003 17.8 10.3 0.003 17.8 10.3 5.4 2 1 3 5 5 3 1 ABC transporter C-terminal domain TPR_MLP1_2 PF07926.12 CRK05619.1 - 0.0046 17.0 20.8 0.0046 17.0 20.8 4.6 1 1 2 4 4 4 2 TPR/MLP1/MLP2-like protein HALZ PF02183.18 CRK05619.1 - 0.0074 16.5 0.4 0.0074 16.5 0.4 4.3 5 1 0 5 5 3 1 Homeobox associated leucine zipper MscS_porin PF12795.7 CRK05619.1 - 0.029 13.9 55.5 0.92 9.0 17.6 3.5 2 1 1 3 3 3 0 Mechanosensitive ion channel porin domain Prominin PF05478.11 CRK05619.1 - 0.32 8.9 19.3 0.11 10.4 6.7 2.2 1 1 1 2 2 2 0 Prominin KxDL PF10241.9 CRK05619.1 - 0.39 11.0 21.6 0.73 10.1 3.0 4.5 2 2 2 4 4 4 0 Uncharacterized conserved protein Golgin_A5 PF09787.9 CRK05619.1 - 0.52 9.7 53.0 0.33 10.4 25.4 3.4 1 1 2 3 3 3 0 Golgin subfamily A member 5 SHE3 PF17078.5 CRK05619.1 - 0.58 9.8 28.3 0.36 10.5 11.9 2.4 1 1 2 3 3 3 0 SWI5-dependent HO expression protein 3 Fib_alpha PF08702.10 CRK05619.1 - 0.69 10.1 29.4 12 6.1 0.7 4.0 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family Exonuc_VII_L PF02601.15 CRK05619.1 - 0.96 8.9 40.0 0.23 11.0 17.3 2.4 1 1 1 2 2 2 0 Exonuclease VII, large subunit Occludin_ELL PF07303.13 CRK05619.1 - 1.7 9.4 26.6 0.65 10.8 0.9 4.5 1 1 3 5 5 5 0 Occludin homology domain IFT57 PF10498.9 CRK05619.1 - 1.7 7.5 39.7 0.78 8.6 21.7 2.7 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 FapA PF03961.13 CRK05619.1 - 1.8 7.1 35.2 0.035 12.7 2.9 3.1 1 1 2 3 3 3 0 Flagellar Assembly Protein A DUF1664 PF07889.12 CRK05619.1 - 3.2 7.8 25.5 2.1 8.4 6.0 4.0 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 CRK05619.1 - 3.4 6.9 61.0 2.3 7.5 17.5 3.3 1 1 1 3 3 3 0 Domain of unknown function (DUF4407) NPV_P10 PF05531.12 CRK05619.1 - 5.1 7.6 20.9 0.15 12.5 2.1 4.9 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein Jnk-SapK_ap_N PF09744.9 CRK05619.1 - 7.6 6.7 52.7 0.76 10.0 21.0 3.5 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 RasGAP_C PF03836.15 CRK05619.1 - 9.7 6.3 29.0 1.6 8.8 8.9 4.2 1 1 4 5 5 5 0 RasGAP C-terminus RRM_1 PF00076.22 CRK05627.1 - 2.8e-18 65.5 0.0 5.6e-18 64.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CRK05627.1 - 0.00039 20.3 0.1 0.00093 19.2 0.1 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 CRK05627.1 - 0.011 15.3 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 CRK05627.1 - 0.026 14.8 3.8 0.14 12.4 0.0 3.1 3 1 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter Na_trans_assoc PF06512.13 CRK05627.1 - 0.99 9.7 8.4 1.7 8.9 8.4 1.5 1 0 0 1 1 1 0 Sodium ion transport-associated PUF PF00806.19 CRK05646.1 - 1.2e-58 191.6 9.8 2.4e-07 30.1 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat DUF445 PF04286.12 CRK05646.1 - 0.17 11.6 0.0 1.1 9.0 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF445) RNA_pol_Rpb2_1 PF04563.15 CRK05653.1 - 4.3e-56 189.6 0.1 5.4e-56 189.3 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 CRK05653.1 - 4.4e-28 98.2 0.1 1.4e-27 96.5 0.1 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.16 CRK05653.1 - 6.4e-21 74.3 0.0 1.3e-20 73.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_6 PF00562.28 CRK05661.1 - 3.7e-54 184.3 0.0 5.3e-54 183.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_7 PF04560.20 CRK05661.1 - 7.9e-34 115.9 0.9 1.3e-33 115.2 0.9 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_1 PF04563.15 CRK05661.1 - 2.9e-16 59.6 0.0 4.4e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit Agro_virD5 PF04730.12 CRK05661.1 - 0.1 11.1 0.0 0.23 9.9 0.0 1.6 2 0 0 2 2 2 0 Agrobacterium VirD5 protein NRDD PF13597.6 CRK05661.1 - 0.23 10.2 0.8 0.44 9.3 0.8 1.3 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase RNA_pol_Rpb2_6 PF00562.28 CRK05669.1 - 1.6e-119 399.5 0.0 2e-119 399.2 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 MMU163 PF17119.5 CRK05669.1 - 3.5e-69 232.7 4.3 1.5e-50 171.7 0.6 2.2 1 1 1 2 2 2 2 Mitochondrial protein up-regulated during meiosis RNA_pol_Rpb2_7 PF04560.20 CRK05669.1 - 1.4e-24 86.3 0.2 2.6e-24 85.4 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 YL1_C PF08265.11 CRK05669.1 - 0.027 14.2 0.1 0.058 13.2 0.1 1.6 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain DUF5058 PF16481.5 CRK05669.1 - 0.041 13.6 0.0 0.064 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5058) MMU163 PF17119.5 CRK05677.1 - 1.8e-21 76.5 0.4 2.7e-18 66.0 0.2 2.0 1 1 1 2 2 2 2 Mitochondrial protein up-regulated during meiosis Citrate_bind PF16114.5 CRK05683.1 - 3.9e-86 287.1 0.1 5.5e-86 286.6 0.1 1.2 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding ATP-grasp_2 PF08442.10 CRK05683.1 - 3.7e-09 36.4 0.0 5.7e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Reovirus_M2 PF05993.12 CRK05683.1 - 0.016 13.4 0.0 0.024 12.8 0.0 1.2 1 0 0 1 1 1 0 Reovirus major virion structural protein Mu-1/Mu-1C (M2) CoA_binding PF02629.19 CRK05692.1 - 1.9e-20 73.3 0.1 7.5e-20 71.4 0.0 1.8 2 0 0 2 2 2 1 CoA binding domain CEP1-DNA_bind PF09287.10 CRK05692.1 - 0.082 12.6 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 CEP-1, DNA binding CoA_binding PF02629.19 CRK05706.1 - 3.5e-20 72.5 0.1 1.3e-18 67.5 0.0 2.5 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 CRK05706.1 - 8e-16 58.2 0.1 1.5e-15 57.3 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 CRK05706.1 - 3.9e-06 26.7 0.0 0.00012 21.8 0.0 2.3 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain Citrate_synt PF00285.21 CRK05706.1 - 0.13 11.3 0.0 0.53 9.3 0.0 1.8 1 1 0 1 1 1 0 Citrate synthase, C-terminal domain TPR_10 PF13374.6 CRK05714.1 - 7.2e-41 137.0 18.2 1.2e-06 28.1 0.3 7.2 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_12 PF13424.6 CRK05714.1 - 6.7e-40 135.3 17.1 1.8e-09 37.8 1.3 5.5 2 1 2 5 5 5 5 Tetratricopeptide repeat TPR_MalT PF17874.1 CRK05714.1 - 2.1e-07 30.7 19.5 8.2e-05 22.1 6.1 2.1 1 1 0 2 2 2 2 MalT-like TPR region TPR_7 PF13176.6 CRK05714.1 - 4e-06 26.5 10.8 0.8 9.9 0.0 6.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 CRK05714.1 - 4.9e-06 26.9 19.4 3.2 8.8 0.1 6.7 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 CRK05714.1 - 1.9e-05 25.2 16.1 0.44 11.2 1.2 5.6 5 2 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 CRK05714.1 - 4.2e-05 24.0 20.1 0.18 12.3 0.8 5.7 2 2 4 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 CRK05714.1 - 9.1e-05 22.3 14.7 1.5 9.1 0.1 6.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.28 CRK05714.1 - 0.0032 17.2 5.7 4.7 7.2 0.0 4.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 CRK05714.1 - 0.07 13.4 4.8 18 5.9 0.0 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CRK05714.1 - 0.91 9.8 6.8 14 6.0 0.2 4.3 2 2 2 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 CRK05714.1 - 1.2 10.0 28.1 9.7 7.2 0.2 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat SOAR PF16533.5 CRK05714.1 - 1.7 8.6 4.9 1.4 9.0 1.3 2.6 3 0 0 3 3 3 0 STIM1 Orai1-activating region Citrate_synt PF00285.21 CRK05717.1 - 0.095 11.8 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Citrate synthase, C-terminal domain TPR_12 PF13424.6 CRK05724.1 - 5.3e-38 129.2 23.6 6.3e-09 36.0 2.4 6.7 4 1 2 6 6 6 6 Tetratricopeptide repeat TPR_10 PF13374.6 CRK05724.1 - 6.1e-37 124.5 22.5 1e-06 28.4 0.5 8.1 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_MalT PF17874.1 CRK05724.1 - 7.9e-05 22.2 23.3 0.0059 16.0 10.8 3.2 1 1 2 3 3 3 2 MalT-like TPR region TPR_16 PF13432.6 CRK05724.1 - 0.0023 18.5 15.0 0.86 10.3 0.3 6.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 CRK05724.1 - 0.007 17.1 18.6 33 5.7 0.3 7.8 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_19 PF14559.6 CRK05724.1 - 0.015 15.8 17.7 0.92 10.1 2.8 6.1 4 2 4 8 8 8 0 Tetratricopeptide repeat NACHT PF05729.12 CRK05724.1 - 0.041 13.8 0.0 0.63 9.9 0.0 2.4 2 0 0 2 2 2 0 NACHT domain TPR_7 PF13176.6 CRK05724.1 - 0.21 11.7 9.6 28 5.1 0.0 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.17 CRK05724.1 - 1.7 8.9 16.9 22 5.5 0.1 7.0 9 0 0 9 9 9 0 Tetratricopeptide repeat Ribosomal_L30 PF00327.20 CRK05729.1 - 1.3e-16 60.2 0.1 1.7e-16 59.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e MRG PF05712.13 CRK05735.1 - 9.2e-60 201.4 0.0 1.9e-59 200.3 0.0 1.5 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 CRK05735.1 - 1.1e-08 34.9 1.6 2.7e-08 33.6 1.6 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Cnl2_NKP2 PF09447.10 CRK05744.1 - 3.7e-27 94.3 1.3 6e-27 93.6 0.6 1.7 1 1 1 2 2 2 1 Cnl2/NKP2 family protein OmpH PF03938.14 CRK05744.1 - 0.00096 19.5 1.1 0.76 10.1 0.3 2.1 2 0 0 2 2 2 2 Outer membrane protein (OmpH-like) CENP-F_leu_zip PF10473.9 CRK05744.1 - 0.006 16.6 2.6 0.012 15.6 1.6 1.9 1 1 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF5082 PF16888.5 CRK05744.1 - 0.014 15.6 1.6 0.04 14.2 0.1 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF5082) Prefoldin_2 PF01920.20 CRK05744.1 - 0.018 15.0 0.2 0.018 15.0 0.2 2.1 2 1 1 3 3 3 0 Prefoldin subunit DUF4407 PF14362.6 CRK05744.1 - 0.023 14.1 0.7 0.028 13.8 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3209 PF11483.8 CRK05744.1 - 0.036 14.5 1.9 0.062 13.8 1.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3209) Seryl_tRNA_N PF02403.22 CRK05744.1 - 0.053 13.8 3.5 1.5 9.1 0.2 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain T6PP_N PF18572.1 CRK05744.1 - 0.055 13.3 0.4 0.086 12.7 0.4 1.3 1 0 0 1 1 1 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain Nnf1 PF03980.14 CRK05744.1 - 0.067 13.6 4.7 0.062 13.7 2.2 2.0 1 1 1 2 2 2 0 Nnf1 DASH_Spc19 PF08287.11 CRK05744.1 - 0.07 13.0 2.3 0.11 12.4 0.1 2.0 2 0 0 2 2 2 0 Spc19 SlyX PF04102.12 CRK05744.1 - 0.085 13.5 3.1 0.13 12.9 0.1 2.4 2 1 0 2 2 2 0 SlyX APG6_N PF17675.1 CRK05744.1 - 0.32 11.5 6.6 1.4 9.5 6.7 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region ZapB PF06005.12 CRK05744.1 - 0.42 11.1 0.1 0.42 11.1 0.1 2.4 2 1 0 2 2 2 0 Cell division protein ZapB DivIC PF04977.15 CRK05744.1 - 0.91 9.3 5.7 0.35 10.7 0.2 2.3 2 0 0 2 2 2 0 Septum formation initiator PRKG1_interact PF15898.5 CRK05744.1 - 1.9 9.4 6.3 19 6.2 6.3 2.1 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain CENP-Q PF13094.6 CRK05754.1 - 6e-42 143.7 0.1 6e-42 143.7 0.1 2.4 2 0 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit Myc_N PF01056.18 CRK05765.1 - 0.021 14.7 5.7 0.27 11.1 0.7 2.2 2 0 0 2 2 2 0 Myc amino-terminal region RXT2_N PF08595.11 CRK05765.1 - 0.088 12.8 6.2 4.1 7.4 0.1 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal PPP4R2 PF09184.11 CRK05765.1 - 0.44 10.1 7.8 0.94 9.0 1.8 2.2 2 0 0 2 2 2 0 PPP4R2 Pox_Ag35 PF03286.14 CRK05765.1 - 0.62 9.8 7.3 0.7 9.7 1.0 2.4 2 0 0 2 2 2 0 Pox virus Ag35 surface protein NOA36 PF06524.12 CRK05765.1 - 2.1 7.6 19.3 2.9 7.1 2.2 2.2 2 0 0 2 2 2 0 NOA36 protein DUF2457 PF10446.9 CRK05765.1 - 3 6.9 20.3 1 8.5 7.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Ribosomal_60s PF00428.19 CRK05765.1 - 3.1 8.5 12.9 4.4 8.0 1.2 2.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein CENP-B_dimeris PF09026.10 CRK05765.1 - 9.1 6.7 28.2 0.92 9.9 5.6 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Prefoldin_2 PF01920.20 CRK05772.1 - 9e-26 89.9 8.8 1.2e-25 89.5 8.8 1.2 1 0 0 1 1 1 1 Prefoldin subunit Takusan PF04822.13 CRK05772.1 - 0.1 12.5 7.1 0.56 10.1 0.6 2.4 2 0 0 2 2 2 0 Takusan XhlA PF10779.9 CRK05772.1 - 0.16 12.2 0.4 0.16 12.2 0.4 2.2 2 1 0 2 2 2 0 Haemolysin XhlA MIF4G_like_2 PF09090.11 CRK05772.1 - 2.8 7.4 7.4 4.5 6.7 7.4 1.5 1 1 0 1 1 1 0 MIF4G like Cauli_AT PF03233.13 CRK05772.1 - 4.7 7.1 8.8 16 5.4 5.6 2.0 2 0 0 2 2 2 0 Aphid transmission protein APG6_N PF17675.1 CRK05772.1 - 9 6.8 18.5 2.5 8.6 1.4 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region CENP-W PF15510.6 CRK05778.1 - 0.018 15.2 0.2 0.018 15.2 0.2 2.0 2 0 0 2 2 2 0 CENP-W protein ELFV_dehydrog PF00208.21 CRK06026.1 - 3.7e-17 62.9 0.1 4.7e-17 62.5 0.1 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TMEM208_SND2 PF05620.11 CRK06198.1 - 7.9e-24 84.3 0.1 8.6e-24 84.2 0.1 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 PS_Dcarbxylase PF02666.15 CRK06306.1 - 5.8e-15 55.4 0.0 8.7e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase CENP-B_N PF04218.13 CRK06306.1 - 0.0057 16.3 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain SfLAP PF11139.8 CRK06306.1 - 0.025 14.0 0.7 0.025 14.0 0.7 1.4 2 0 0 2 2 2 0 Sap, sulfolipid-1-addressing protein GATase_3 PF07685.14 CRK06306.1 - 0.18 11.4 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain PX PF00787.24 CRK06518.1 - 2.5e-05 24.2 0.0 3.5e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 PX domain Oxidored_FMN PF00724.20 CRK06621.1 - 0.24 10.6 0.0 0.25 10.6 0.0 1.1 1 0 0 1 1 1 0 NADH:flavin oxidoreductase / NADH oxidase family zf-H2C2 PF09337.10 CRK06834.1 - 1.9e-15 56.8 1.5 3.4e-15 56.0 1.5 1.4 1 0 0 1 1 1 1 H2C2 zinc finger Integrase_H2C2 PF17921.1 CRK06834.1 - 4.6e-12 45.9 0.1 4.6e-12 45.9 0.1 1.9 2 0 0 2 2 2 1 Integrase zinc binding domain Acetyltransf_1 PF00583.25 CRK06834.1 - 0.00044 20.5 0.0 0.00098 19.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 CRK06834.1 - 0.0075 17.0 0.0 0.021 15.5 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 CRK06834.1 - 0.012 15.7 0.0 0.028 14.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ribosomal_S2 PF00318.20 CRK06836.1 - 1.8e-60 203.9 0.0 2.4e-33 115.2 0.0 2.5 2 0 0 2 2 2 2 Ribosomal protein S2 CBS PF00571.28 CRK06836.1 - 6.5e-29 100.2 1.9 5.6e-09 36.3 0.0 5.0 4 0 0 4 4 4 4 CBS domain Fic PF02661.18 CRK06836.1 - 5.1e-11 43.3 0.0 2.5e-10 41.1 0.0 2.3 2 0 0 2 2 2 1 Fic/DOC family PB1 PF00564.24 CRK06836.1 - 3.4e-07 30.1 0.0 1.2e-06 28.4 0.0 1.9 1 0 0 1 1 1 1 PB1 domain DUF1205 PF06722.12 CRK06836.1 - 0.019 15.0 0.1 0.046 13.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1205) zf-H2C2_2 PF13465.6 CRK06840.1 - 4.1e-05 23.8 7.9 0.0019 18.6 2.9 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 CRK06840.1 - 0.00012 22.3 33.3 0.0016 18.7 7.1 4.1 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 CRK06840.1 - 0.11 12.2 8.6 1.1 9.1 2.7 2.7 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_4 PF13894.6 CRK06840.1 - 0.66 11.0 31.7 0.095 13.6 6.1 4.6 4 0 0 4 4 4 0 C2H2-type zinc finger ABC2_membrane PF01061.24 CRK06843.1 - 1.1e-46 158.9 23.9 4.8e-37 127.4 12.0 2.6 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 CRK06843.1 - 1.9e-38 132.1 0.0 9.2e-20 71.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 CRK06843.1 - 1.4e-30 105.0 0.2 2.6e-25 88.2 0.0 2.6 2 0 0 2 2 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 CRK06843.1 - 1.7e-08 34.0 16.5 2.3e-05 23.7 7.5 2.5 2 1 0 2 2 2 2 ABC-2 family transporter protein ABC_trans_N PF14510.6 CRK06843.1 - 1e-07 32.4 0.1 2.5e-07 31.2 0.1 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_25 PF13481.6 CRK06843.1 - 6.1e-05 22.7 0.0 0.028 14.0 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CRK06843.1 - 0.00029 21.3 0.1 0.07 13.5 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 CRK06843.1 - 0.00031 20.7 0.4 0.0054 16.7 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 CRK06843.1 - 0.00041 20.0 0.5 0.075 12.8 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 CRK06843.1 - 0.00046 20.7 0.0 1.5 9.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 CRK06843.1 - 0.00072 19.5 0.0 1.6 8.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 CRK06843.1 - 0.00095 19.3 0.0 1.2 9.3 0.0 2.6 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.6 CRK06843.1 - 0.0019 18.5 0.3 0.88 9.8 0.1 3.5 3 1 0 3 3 3 1 AAA domain AAA_28 PF13521.6 CRK06843.1 - 0.008 16.4 0.3 0.54 10.5 0.2 2.4 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.9 CRK06843.1 - 0.0089 15.8 0.3 6.6 6.5 0.0 2.5 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.6 CRK06843.1 - 0.011 16.1 0.0 0.93 9.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 CRK06843.1 - 0.017 14.7 0.6 1.7 8.2 0.4 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 CRK06843.1 - 0.052 13.3 0.1 4.4 7.0 0.3 2.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 CRK06843.1 - 0.075 12.9 0.4 2.4 8.0 0.2 2.3 2 0 0 2 2 2 0 NACHT domain SMC_N PF02463.19 CRK06843.1 - 0.17 11.3 0.0 1.3 8.5 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Zn_clus PF00172.18 CRK06848.1 - 0.096 12.8 5.1 0.2 11.8 5.1 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Tra_M PF05261.11 CRK06848.1 - 0.16 11.9 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 TraM protein, DNA-binding HypA PF01155.19 CRK06848.1 - 0.42 10.6 3.4 0.84 9.7 3.4 1.4 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA WSC PF01822.19 CRK06865.1 - 7.6e-13 48.5 13.8 1.6e-12 47.5 13.8 1.5 1 0 0 1 1 1 1 WSC domain SKG6 PF08693.10 CRK06865.1 - 0.00013 21.3 3.9 0.00023 20.5 3.9 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Podoplanin PF05808.11 CRK06865.1 - 0.021 15.0 2.2 0.031 14.4 2.2 1.2 1 0 0 1 1 1 0 Podoplanin PepSY_TM PF03929.16 CRK06865.1 - 0.088 12.5 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 PepSY-associated TM region DUF2749 PF10907.8 CRK06865.1 - 0.1 12.8 0.5 0.32 11.2 0.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) PTP_tm PF18861.1 CRK06865.1 - 0.19 11.7 3.9 0.36 10.8 3.9 1.4 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J zf-MYND PF01753.18 CRK06872.1 - 6.8e-11 42.1 13.1 1.9e-10 40.7 13.1 1.8 1 0 0 1 1 1 1 MYND finger DUF4470 PF14737.6 CRK06872.1 - 6.5e-10 39.1 0.0 2e-09 37.5 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) ECH_1 PF00378.20 CRK06883.1 - 3.2e-37 128.2 0.0 5.3e-29 101.3 0.0 3.3 3 0 0 3 3 3 3 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CRK06883.1 - 8.4e-24 84.7 1.9 1.4e-20 74.1 0.0 2.9 3 0 0 3 3 3 2 Enoyl-CoA hydratase/isomerase DUF883 PF05957.13 CRK06883.1 - 0.032 14.8 5.6 0.088 13.4 4.9 2.2 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) PAS PF00989.25 CRK06883.1 - 0.055 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 PAS fold YtxH PF12732.7 CRK06883.1 - 0.41 11.2 11.2 0.3 11.7 2.9 3.0 1 1 1 2 2 2 0 YtxH-like protein CsbD PF05532.12 CRK06883.1 - 7 6.6 14.7 3.9 7.4 5.6 2.9 2 1 1 3 3 3 0 CsbD-like Kelch_5 PF13854.6 CRK06891.1 - 5.5e-11 42.2 0.5 3.2e-08 33.4 0.0 3.8 4 0 0 4 4 4 1 Kelch motif Ank_2 PF12796.7 CRK06891.1 - 5.7e-09 36.4 0.0 1.4e-08 35.2 0.0 1.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CRK06891.1 - 1.4e-08 34.8 0.0 3.2e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 CRK06891.1 - 9.6e-08 32.2 0.1 1.7e-06 28.2 0.1 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 CRK06891.1 - 9e-07 29.3 0.1 0.00018 22.0 0.0 2.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CRK06891.1 - 6.2e-06 26.2 0.0 0.00024 21.3 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Kelch_6 PF13964.6 CRK06891.1 - 0.002 18.3 4.8 11 6.5 0.0 5.2 5 0 0 5 5 5 1 Kelch motif SKG6 PF08693.10 CRK06891.1 - 0.01 15.2 1.5 0.021 14.3 1.5 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Yip1 PF04893.17 CRK06891.1 - 0.056 13.2 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Yip1 domain Kelch_4 PF13418.6 CRK06891.1 - 2.1 8.4 22.4 1.6 8.8 0.5 5.8 5 3 0 5 5 5 0 Galactose oxidase, central domain Peptidase_S10 PF00450.22 CRK06904.1 - 2.6e-67 228.0 0.0 3.3e-67 227.7 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Hydrolase_4 PF12146.8 CRK06904.1 - 0.03 13.6 0.1 3.4 6.9 0.1 2.7 2 1 1 3 3 3 0 Serine aminopeptidase, S33 Glyco_hydro_12 PF01670.16 CRK06911.1 - 2.4e-46 158.4 6.8 2.7e-46 158.2 6.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 FAD_binding_3 PF01494.19 CRK06918.1 - 5.5e-08 32.4 0.8 0.037 13.3 0.1 3.2 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.6 CRK06918.1 - 0.0087 16.3 0.0 0.018 15.2 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CRK06918.1 - 0.031 13.5 0.0 0.048 12.9 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CRK06918.1 - 0.043 13.8 0.0 0.082 12.9 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding DAO PF01266.24 CRK06918.1 - 0.055 13.0 0.1 0.091 12.3 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Phospholip_A2_3 PF09056.11 CRK06922.1 - 4.3e-43 146.5 0.6 5.5e-43 146.1 0.6 1.1 1 0 0 1 1 1 1 Prokaryotic phospholipase A2 Oxidored_FMN PF00724.20 CRK06929.1 - 9.4e-84 281.6 0.0 1.1e-83 281.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family OAD_gamma PF04277.13 CRK06936.1 - 0.0027 18.2 0.0 0.0027 18.2 0.0 2.9 2 1 0 2 2 2 1 Oxaloacetate decarboxylase, gamma chain FixQ PF05545.11 CRK06936.1 - 0.0034 17.3 0.0 0.0057 16.6 0.0 1.2 1 0 0 1 1 1 1 Cbb3-type cytochrome oxidase component FixQ OAD_gamma PF04277.13 CRK06941.1 - 0.0031 18.1 0.1 0.0031 18.1 0.1 3.4 2 1 0 2 2 2 1 Oxaloacetate decarboxylase, gamma chain FixQ PF05545.11 CRK06941.1 - 0.0036 17.2 0.0 0.0061 16.5 0.0 1.2 1 0 0 1 1 1 1 Cbb3-type cytochrome oxidase component FixQ Glyco_hydro_6 PF01341.17 CRK06946.1 - 1.3e-170 567.0 0.1 3.6e-65 220.7 0.0 3.4 1 1 2 3 3 3 3 Glycosyl hydrolases family 6 ABC_membrane PF00664.23 CRK06946.1 - 3.6e-40 138.4 15.0 4.8e-40 137.9 15.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 CRK06946.1 - 5.4e-34 117.6 0.0 9.8e-34 116.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 CRK06946.1 - 9e-06 26.2 0.0 2.1e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 CRK06946.1 - 0.00013 21.5 0.0 0.017 14.6 0.0 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 CRK06946.1 - 0.00045 20.5 0.0 0.0019 18.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 CRK06946.1 - 0.0033 17.3 0.1 0.079 12.8 0.0 2.3 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 CRK06946.1 - 0.005 16.9 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CRK06946.1 - 0.0052 16.7 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_14 PF13173.6 CRK06946.1 - 0.0075 16.3 0.0 0.034 14.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain AP_endonuc_2 PF01261.24 CRK06946.1 - 0.014 14.9 0.0 19 4.6 0.0 3.4 3 0 0 3 3 3 0 Xylose isomerase-like TIM barrel AAA_33 PF13671.6 CRK06946.1 - 0.017 15.3 0.0 0.2 11.8 0.0 2.8 4 0 0 4 4 3 0 AAA domain AAA PF00004.29 CRK06946.1 - 0.045 14.2 0.0 0.21 12.0 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 CRK06946.1 - 0.067 12.8 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 CRK06946.1 - 0.078 12.2 0.0 0.2 10.9 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.6 CRK06946.1 - 0.079 12.7 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.6 CRK06946.1 - 0.1 12.9 0.0 0.36 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CRK06946.1 - 0.14 11.6 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Septin PF00735.18 CRK06946.1 - 0.17 11.1 0.0 0.3 10.3 0.0 1.3 1 0 0 1 1 1 0 Septin Rad17 PF03215.15 CRK06946.1 - 0.21 11.5 0.0 0.42 10.5 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain MFS_1 PF07690.16 CRK06953.1 - 3.7e-33 114.9 17.8 5.6e-33 114.3 17.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily TauD PF02668.16 CRK06959.1 - 6.6e-64 216.3 1.0 8e-64 216.0 1.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Cupin_1 PF00190.22 CRK06965.1 - 9.1e-16 57.8 0.7 2.6e-13 49.8 0.3 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 CRK06965.1 - 0.0084 15.8 0.1 0.022 14.4 0.1 1.6 1 1 0 1 1 1 1 Cupin domain PHO4 PF01384.20 CRK06971.1 - 1.1e-108 363.3 10.9 1.3e-108 363.1 10.9 1.0 1 0 0 1 1 1 1 Phosphate transporter family Ctr PF04145.15 CRK06989.1 - 3.6e-19 69.9 0.1 4.8e-19 69.5 0.1 1.2 1 0 0 1 1 1 1 Ctr copper transporter family Metallophos PF00149.28 CRK07014.1 - 1.4e-11 45.3 0.2 4.6e-11 43.6 0.2 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Sulfatase PF00884.23 CRK07019.1 - 1.4e-06 28.0 0.0 1.7e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Sulfatase DUF1524 PF07510.11 CRK07026.1 - 1.7e-06 28.0 0.0 2.2e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) HNH_4 PF13395.6 CRK07026.1 - 0.099 12.6 0.0 3.5 7.6 0.0 2.2 2 0 0 2 2 2 0 HNH endonuclease Glyco_hydro_16 PF00722.21 CRK07037.1 - 1.6e-42 145.0 0.3 3.1e-42 144.0 0.3 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Sec7 PF01369.20 CRK07041.1 - 4.4e-28 98.2 0.0 8.4e-28 97.3 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 CRK07041.1 - 2.4e-18 66.6 0.1 5.7e-18 65.4 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Abhydrolase_3 PF07859.13 CRK07048.1 - 8.5e-43 146.7 0.0 1.5e-42 145.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CRK07048.1 - 1.4e-06 28.0 0.0 0.0014 18.1 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.28 CRK07048.1 - 9.6e-06 24.7 0.0 6.5e-05 22.0 0.0 1.9 1 1 0 1 1 1 1 Carboxylesterase family Esterase PF00756.20 CRK07048.1 - 0.025 14.2 0.0 0.06 13.0 0.0 1.5 2 0 0 2 2 2 0 Putative esterase Abhydrolase_6 PF12697.7 CRK07048.1 - 0.079 13.5 8.3 0.025 15.2 5.0 1.7 1 1 1 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 CRK07048.1 - 0.093 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase SRP-alpha_N PF04086.13 CRK07053.1 - 4.4e-18 66.2 0.0 5.1e-18 66.0 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal YIF1 PF03878.15 CRK07060.1 - 1.6e-43 149.0 0.8 1.9e-43 148.7 0.8 1.1 1 0 0 1 1 1 1 YIF1 Malic_M PF03949.15 CRK07285.1 - 2.8e-13 49.7 2.3 3.5e-13 49.4 2.3 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 CRK07285.1 - 7.6e-08 32.4 0.2 1.2e-07 31.7 0.2 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain PMM PF03332.13 CRK07375.1 - 3.8e-80 268.8 0.0 4.9e-80 268.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Na_Ca_ex PF01699.24 CRK07375.1 - 2.6e-28 98.9 16.9 3.9e-28 98.3 16.9 1.3 1 0 0 1 1 1 1 Sodium/calcium exchanger protein p53-inducible11 PF14936.6 CRK07375.1 - 0.033 14.3 3.0 0.093 12.8 1.5 2.1 1 1 1 2 2 2 0 Tumour protein p53-inducible protein 11 YMF19 PF02326.15 CRK07375.1 - 0.033 15.0 0.0 0.1 13.4 0.0 1.8 1 0 0 1 1 1 0 Plant ATP synthase F0 DUF5592 PF17332.2 CRK07375.1 - 0.081 13.5 2.3 0.14 12.7 2.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5592) SEN1_N PF12726.7 CRK07724.1 - 0.00081 17.8 0.1 0.00081 17.8 0.1 1.2 1 0 0 1 1 1 1 SEN1 N terminal bZIP_1 PF00170.21 CRK07898.1 - 1.9e-10 40.7 5.0 3.6e-10 39.8 5.0 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CRK07898.1 - 8.3e-05 22.6 7.4 0.00013 21.9 7.4 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 CRK07898.1 - 9.8e-05 22.8 2.9 0.00017 22.0 2.9 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor Condensation PF00668.20 CRK07902.1 - 9.9e-64 215.7 0.0 6.3e-29 100.9 0.0 4.7 3 2 0 3 3 3 3 Condensation domain AMP-binding PF00501.28 CRK07902.1 - 6.8e-33 113.9 0.0 9.9e-33 113.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 CRK07902.1 - 5.6e-15 55.4 2.6 2.3e-05 24.6 0.0 4.2 3 0 0 3 3 3 3 Phosphopantetheine attachment site Abhydrolase_3 PF07859.13 CRK07911.1 - 9.4e-28 97.5 0.0 1.6e-27 96.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Cyt-b5 PF00173.28 CRK07911.1 - 4.1e-12 46.1 0.0 8.9e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FAD_binding_1 PF00667.20 CRK07911.1 - 4.8e-11 42.7 0.0 1.4e-10 41.2 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain IDO PF01231.18 CRK07911.1 - 1.2e-08 34.2 0.0 6.1e-08 31.9 0.0 1.9 2 0 0 2 2 2 1 Indoleamine 2,3-dioxygenase NAD_binding_1 PF00175.21 CRK07911.1 - 2.3e-08 34.7 0.0 4.8e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain COesterase PF00135.28 CRK07911.1 - 0.036 13.0 0.0 0.057 12.3 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family SecA_SW PF07516.13 CRK07911.1 - 0.16 12.0 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 SecA Wing and Scaffold domain SAPS PF04499.15 CRK07919.1 - 5.9e-189 628.9 1.0 1.6e-187 624.2 0.0 3.2 2 1 0 2 2 2 1 SIT4 phosphatase-associated protein zf-LITAF-like PF10601.9 CRK07927.1 - 3.9e-19 68.7 4.8 4.9e-19 68.4 4.8 1.1 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain zf-TFIIB PF13453.6 CRK07927.1 - 0.031 13.6 0.2 4.8 6.6 0.0 2.3 2 0 0 2 2 2 0 Transcription factor zinc-finger WD40 PF00400.32 CRK07932.1 - 8.5e-46 153.0 13.9 6.7e-09 36.2 0.8 7.5 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK07932.1 - 8.4e-10 38.8 0.0 0.0037 17.5 0.0 3.9 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CRK07932.1 - 5e-07 28.7 0.0 0.00042 19.1 0.0 3.0 3 1 0 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 CRK07932.1 - 0.00023 20.1 0.0 0.062 12.0 0.0 2.8 3 0 0 3 3 3 2 Nup133 N terminal like LexA_DNA_bind PF01726.16 CRK07932.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 LexA DNA binding domain EzrA PF06160.12 CRK07942.1 - 0.042 12.0 0.0 0.06 11.5 0.0 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Paf1 PF03985.13 CRK07954.1 - 1.2e-79 268.3 0.0 1.4e-79 268.1 0.0 1.0 1 0 0 1 1 1 1 Paf1 Glyco_transf_90 PF05686.12 CRK07959.1 - 2.9e-15 56.1 9.5 1.1e-13 50.8 6.8 3.0 2 1 0 2 2 2 2 Glycosyl transferase family 90 Ribosomal_S8 PF00410.19 CRK07963.1 - 7.3e-22 77.7 0.0 9.6e-22 77.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_L7Ae PF01248.26 CRK07968.1 - 2.5e-27 94.4 0.9 3.2e-27 94.1 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 CRK07968.1 - 0.082 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 PELOTA RNA binding domain Rotamase_3 PF13616.6 CRK07975.1 - 1.1e-15 58.2 0.1 2.3e-15 57.1 0.1 1.6 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 CRK07975.1 - 1.5e-13 51.5 0.0 2.4e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 CRK07975.1 - 0.00014 22.7 0.5 0.00054 20.8 0.0 1.8 1 1 0 2 2 2 1 PPIC-type PPIASE domain Ribosomal_L37ae PF01780.19 CRK07980.1 - 7.5e-41 138.1 8.5 8.4e-41 138.0 8.5 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family DUF1451 PF07295.11 CRK07980.1 - 0.05 13.6 1.2 0.07 13.2 1.2 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain Zn_Tnp_IS1595 PF12760.7 CRK07980.1 - 0.052 13.5 4.4 0.083 12.9 4.4 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain C1_2 PF03107.16 CRK07980.1 - 0.059 13.7 2.3 1.8 8.9 2.5 2.1 1 1 1 2 2 2 0 C1 domain zf-H2C2_2 PF13465.6 CRK07980.1 - 1.9 9.1 6.3 9.7 6.8 1.2 2.3 1 1 1 2 2 2 0 Zinc-finger double domain DUF155 PF02582.14 CRK07989.1 - 5.3e-06 26.6 0.0 7.2e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 UPF0449 PF15136.6 CRK07989.1 - 0.064 13.7 0.0 0.074 13.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 HMG_box PF00505.19 CRK07993.1 - 2.8e-09 37.3 0.7 8.5e-09 35.7 0.7 1.9 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CRK07993.1 - 0.00013 22.4 3.7 0.00015 22.3 1.7 2.2 2 0 0 2 2 2 1 HMG-box domain Cpn60_TCP1 PF00118.24 CRK07998.1 - 5.1e-152 506.9 7.0 5.8e-152 506.8 7.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PrpR_N PF06506.11 CRK07998.1 - 0.037 13.6 0.3 0.13 11.8 0.1 2.0 2 0 0 2 2 2 0 Propionate catabolism activator EAL PF00563.20 CRK07998.1 - 0.057 12.9 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 EAL domain LPG_synthase_TM PF03706.13 CRK08003.1 - 0.0084 15.7 0.3 0.011 15.2 0.3 1.1 1 0 0 1 1 1 1 Lysylphosphatidylglycerol synthase TM region PH_10 PF15411.6 CRK08008.1 - 2.3e-29 102.1 1.0 5.3e-29 101.0 1.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain VWA PF00092.28 CRK08008.1 - 5.2e-15 56.1 0.0 9.2e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 CRK08008.1 - 3.3e-11 43.4 0.0 9.6e-11 41.9 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CRK08008.1 - 2.6e-07 31.2 0.0 6.1e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-RING_2 PF13639.6 CRK08008.1 - 0.00024 21.4 6.1 0.00042 20.6 6.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 CRK08008.1 - 0.00035 20.5 6.4 0.0006 19.7 6.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 CRK08008.1 - 0.0083 15.7 3.1 0.0083 15.7 3.1 1.7 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 CRK08008.1 - 0.012 15.9 3.2 0.025 14.8 3.2 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain PH PF00169.29 CRK08008.1 - 0.013 16.0 0.1 0.043 14.3 0.1 1.8 1 0 0 1 1 1 0 PH domain zf-RING-like PF08746.11 CRK08008.1 - 0.017 15.4 4.5 0.03 14.6 4.5 1.4 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_3 PF13920.6 CRK08008.1 - 0.042 13.7 2.8 0.076 12.9 2.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CRK08008.1 - 0.047 13.5 5.2 0.087 12.7 5.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CRK08008.1 - 0.094 12.6 6.0 0.18 11.7 6.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CRK08008.1 - 0.18 11.6 4.7 0.36 10.6 4.7 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-UDP PF14569.6 CRK08008.1 - 0.18 11.9 0.7 0.35 11.0 0.7 1.4 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C3H2C3 PF17122.5 CRK08008.1 - 0.38 10.8 5.1 0.84 9.7 5.1 1.6 1 1 0 1 1 1 0 Zinc-finger Prok-RING_4 PF14447.6 CRK08008.1 - 4.1 7.3 4.7 7.5 6.5 4.7 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 CRK08008.1 - 4.3 7.4 5.8 12 6.0 5.8 1.8 1 0 0 1 1 1 0 RING-type zinc-finger Spt20 PF12090.8 CRK08008.1 - 9 5.8 9.2 19 4.8 9.2 1.5 1 0 0 1 1 1 0 Spt20 family U3_snoRNA_assoc PF08297.11 CRK08015.1 - 6.5e-13 49.2 0.4 6.5e-13 49.2 0.4 3.8 3 2 0 3 3 3 1 U3 snoRNA associated DALR_2 PF09190.11 CRK08015.1 - 0.025 15.1 2.6 0.092 13.2 2.6 2.0 1 0 0 1 1 1 0 DALR domain Sel1 PF08238.12 CRK08020.1 - 0.0079 16.9 0.2 0.028 15.1 0.0 2.1 2 0 0 2 2 2 1 Sel1 repeat TP2 PF01254.18 CRK08020.1 - 1.3 9.6 7.7 2.5 8.7 7.7 1.4 1 0 0 1 1 1 0 Nuclear transition protein 2 TPR_4 PF07721.14 CRK08020.1 - 5.4 7.9 15.5 0.56 11.0 3.3 4.4 3 1 1 4 4 4 0 Tetratricopeptide repeat ABM PF03992.16 CRK08025.1 - 6e-09 35.9 0.1 8.2e-08 32.3 0.1 2.1 1 1 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Thiamine_BP PF01910.17 CRK08034.1 - 1.3e-30 105.2 0.1 2.1e-30 104.5 0.1 1.3 1 0 0 1 1 1 1 Thiamine-binding protein SAD_SRA PF02182.17 CRK08034.1 - 6.2e-06 26.0 0.0 1.1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 SAD/SRA domain Baculo_F PF12259.8 CRK08034.1 - 0.097 11.2 0.0 0.13 10.8 0.0 1.1 1 0 0 1 1 1 0 Baculovirus F protein DUF1682 PF07946.14 CRK08037.1 - 2.5e-55 188.0 10.3 1.1e-40 139.8 9.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1682) MRP-S26 PF14943.6 CRK08037.1 - 0.11 12.4 10.0 0.16 11.9 10.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 DUF4407 PF14362.6 CRK08037.1 - 2.1 7.6 8.1 4.6 6.5 8.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Abhydrolase_3 PF07859.13 CRK08041.1 - 3.2e-46 157.8 0.5 6e-46 156.9 0.5 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Haspin_kinase PF12330.8 CRK08041.1 - 3.2e-31 108.6 0.0 4.4e-31 108.1 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain COesterase PF00135.28 CRK08041.1 - 2.9e-06 26.4 0.0 4.6e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family L_protein_N PF15518.6 CRK08041.1 - 0.031 14.1 0.1 0.077 12.8 0.1 1.6 1 0 0 1 1 1 0 L protein N-terminus DLH PF01738.18 CRK08041.1 - 0.096 12.2 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 Dienelactone hydrolase family Ecl1 PF12855.7 CRK08047.1 - 5.2e-37 128.7 18.9 5.2e-37 128.7 18.9 2.0 2 0 0 2 2 2 1 ECL1/2/3 zinc binding proteins zf-FLZ PF04570.14 CRK08047.1 - 0.03 13.8 2.9 0.06 12.8 2.9 1.5 1 0 0 1 1 1 0 zinc-finger of the FCS-type, C2-C2 PLATZ PF04640.14 CRK08047.1 - 0.053 14.1 0.8 0.089 13.4 0.8 1.3 1 0 0 1 1 1 0 PLATZ transcription factor DUF2256 PF10013.9 CRK08047.1 - 2.6 8.2 4.4 36 4.6 4.4 2.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) Kelch_5 PF13854.6 CRK08054.1 - 7.1e-11 41.8 9.7 7.5e-08 32.2 0.0 5.4 5 0 0 5 5 5 2 Kelch motif Kelch_6 PF13964.6 CRK08054.1 - 7e-08 32.5 7.4 0.092 13.1 0.0 5.6 4 1 1 5 5 5 2 Kelch motif Kelch_2 PF07646.15 CRK08054.1 - 1.8e-07 30.9 4.4 0.46 10.6 0.0 5.8 6 0 0 6 6 6 2 Kelch motif Kelch_4 PF13418.6 CRK08054.1 - 3.8e-07 30.0 12.1 0.024 14.7 0.0 5.6 6 1 0 6 6 6 3 Galactose oxidase, central domain Kelch_3 PF13415.6 CRK08054.1 - 0.00017 21.8 5.2 1.7 9.0 0.0 5.5 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_1 PF01344.25 CRK08054.1 - 0.00061 19.3 2.6 11 5.6 0.0 5.1 5 1 0 5 5 5 1 Kelch motif TFIIA PF03153.13 CRK08054.1 - 0.077 13.0 16.1 0.11 12.4 16.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit EphA2_TM PF14575.6 CRK08054.1 - 0.078 13.9 1.0 0.39 11.6 0.0 2.4 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain IPTL-CTERM PF18203.1 CRK08054.1 - 0.75 9.8 7.0 3.1 7.8 7.0 2.2 1 0 0 1 1 1 0 IPTL-CTERM motif SYF2 PF08231.12 CRK08059.1 - 1.3e-35 123.2 6.6 1.3e-35 123.2 6.6 1.7 2 1 0 2 2 2 1 SYF2 splicing factor NAD_binding_10 PF13460.6 CRK08064.1 - 5.2e-08 33.0 0.0 8.6e-07 29.0 0.0 2.6 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 CRK08064.1 - 8.2e-07 28.7 0.0 1.6e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CRK08064.1 - 0.00019 20.5 0.0 0.0018 17.3 0.0 2.1 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 CRK08064.1 - 0.002 17.4 0.0 0.02 14.0 0.0 2.3 3 1 1 4 4 4 1 Male sterility protein RmlD_sub_bind PF04321.17 CRK08064.1 - 0.0099 15.0 0.0 0.091 11.8 0.0 2.4 3 0 0 3 3 3 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 CRK08064.1 - 0.023 14.1 0.0 0.031 13.7 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase YEATS PF03366.16 CRK08070.1 - 8.4e-29 99.4 0.2 1.2e-28 98.8 0.2 1.3 1 0 0 1 1 1 1 YEATS family PhaP_Bmeg PF09602.10 CRK08070.1 - 0.11 12.4 1.1 0.18 11.7 1.1 1.2 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Ins_P5_2-kin PF06090.12 CRK08075.1 - 6.9e-35 121.1 0.0 1.8e-34 119.7 0.0 1.6 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase HMG14_17 PF01101.18 CRK08075.1 - 0.097 13.6 6.6 0.32 12.0 6.6 1.9 1 0 0 1 1 1 0 HMG14 and HMG17 DUF3482 PF11981.8 CRK08078.1 - 0.06 12.7 0.3 0.083 12.3 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) Nucleoside_tran PF01733.18 CRK08081.1 - 1.8e-35 122.8 3.5 1.8e-35 122.8 3.5 2.3 2 1 0 2 2 2 1 Nucleoside transporter MFS_1 PF07690.16 CRK08081.1 - 1.7 7.5 44.4 0.086 11.7 5.1 2.7 1 1 1 2 2 2 0 Major Facilitator Superfamily Catalase PF00199.19 CRK08084.1 - 7.5e-161 535.5 0.1 9.2e-161 535.2 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase_C PF18011.1 CRK08084.1 - 9.8e-46 155.2 0.0 1.5e-45 154.5 0.0 1.3 1 0 0 1 1 1 1 C-terminal domain found in long catalases Catalase-rel PF06628.12 CRK08084.1 - 5.3e-18 65.0 0.1 9.5e-18 64.2 0.1 1.4 1 0 0 1 1 1 1 Catalase-related immune-responsive PhoLip_ATPase_C PF16212.5 CRK08089.1 - 1.2e-81 274.2 18.2 1.2e-81 274.2 18.2 1.9 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CRK08089.1 - 1.2e-26 92.2 4.7 3.5e-26 90.7 4.7 1.9 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 CRK08089.1 - 5e-11 42.5 0.0 4e-10 39.7 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CRK08089.1 - 3.2e-10 40.7 4.7 1.3e-05 25.6 1.4 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 CRK08089.1 - 2.6e-08 33.6 0.1 2.6e-08 33.6 0.1 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CRK08089.1 - 0.0016 18.3 0.1 0.0078 16.0 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Mt_ATP-synt_B PF05405.14 CRK08089.1 - 0.019 14.6 0.1 0.049 13.3 0.1 1.7 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) AA_permease PF00324.21 CRK08093.1 - 9.3e-124 413.6 38.5 1.1e-123 413.4 38.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CRK08093.1 - 1.3e-32 113.2 43.9 1.8e-32 112.7 43.9 1.0 1 0 0 1 1 1 1 Amino acid permease DUF2101 PF09874.9 CRK08093.1 - 6.6 6.4 12.4 0.99 9.1 4.5 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2101) Cript PF10235.9 CRK08095.1 - 9.7e-20 71.0 8.5 9.7e-20 71.0 8.5 1.3 2 0 0 2 2 2 1 Microtubule-associated protein CRIPT DUF2039 PF10217.9 CRK08095.1 - 0.0018 18.6 4.4 0.0018 18.6 4.4 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2039) zinc-ribbons_6 PF07191.12 CRK08095.1 - 0.045 13.7 7.1 0.074 13.0 4.7 2.0 2 0 0 2 2 2 0 zinc-ribbons SARG PF15385.6 CRK08095.1 - 0.06 12.6 0.5 0.07 12.4 0.5 1.1 1 0 0 1 1 1 0 Specifically androgen-regulated gene protein DZR PF12773.7 CRK08095.1 - 3.4 7.8 16.4 1.1 9.4 9.4 2.7 1 1 1 2 2 2 0 Double zinc ribbon zinc_ribbon_15 PF17032.5 CRK08095.1 - 3.8 8.3 10.9 2.5 8.9 6.2 2.6 2 1 0 2 2 2 0 zinc-ribbon family Abhydrolase_1 PF00561.20 CRK08098.1 - 1.7e-19 70.5 0.1 1.9e-15 57.2 0.0 2.0 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CRK08098.1 - 3.7e-16 60.4 4.6 5.5e-16 59.8 4.6 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CRK08098.1 - 3.1e-12 46.3 0.0 2e-11 43.6 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Pinin_SDK_memA PF04696.13 CRK08100.1 - 8e-34 116.5 10.9 8e-34 116.5 10.9 1.7 2 0 0 2 2 2 1 pinin/SDK/memA/ protein conserved region LAT2 PF15703.5 CRK08100.1 - 0.14 12.0 4.7 0.27 11.1 4.7 1.5 1 0 0 1 1 1 0 Linker for activation of T-cells family member 2 GET2 PF08690.10 CRK08100.1 - 6.6 6.3 10.0 0.14 11.8 2.6 1.8 2 0 0 2 2 2 0 GET complex subunit GET2 DUF919 PF06034.11 CRK08100.1 - 7.1 6.6 10.4 24 4.8 10.4 1.8 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) PHF5 PF03660.14 CRK08106.1 - 1.2e-51 173.3 11.0 1.3e-51 173.1 11.0 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 CRK08106.1 - 0.42 8.4 6.8 0.44 8.4 6.8 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DZR PF12773.7 CRK08106.1 - 1 9.4 16.6 3 7.9 2.4 2.9 1 1 1 2 2 2 0 Double zinc ribbon Pex26 PF07163.12 CRK08110.1 - 0.0037 16.6 2.8 0.0069 15.7 2.8 1.4 1 0 0 1 1 1 1 Pex26 protein Mei5 PF10376.9 CRK08110.1 - 0.88 9.4 9.5 1.5 8.7 9.5 1.3 1 0 0 1 1 1 0 Double-strand recombination repair protein CAF1 PF04857.20 CRK08115.1 - 3.3e-54 184.2 0.0 3.8e-54 184.0 0.0 1.0 1 0 0 1 1 1 1 CAF1 family ribonuclease Sedlin_N PF04628.13 CRK08115.1 - 0.13 12.4 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Sedlin, N-terminal conserved region zf-Tim10_DDP PF02953.15 CRK08209.1 - 5.9e-15 54.7 2.1 8.6e-15 54.1 2.1 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger c-SKI_SMAD_bind PF08782.10 CRK08209.1 - 0.018 15.3 0.7 0.019 15.2 0.7 1.1 1 0 0 1 1 1 0 c-SKI Smad4 binding domain Glyco_hydro_72 PF03198.14 CRK08256.1 - 0.006 15.9 0.1 0.0069 15.7 0.1 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_72 PF03198.14 CRK08261.1 - 1e-88 297.7 2.8 1e-88 297.7 2.8 2.1 2 0 0 2 2 2 1 Glucanosyltransferase FCH PF00611.23 CRK08261.1 - 1.7e-26 92.3 1.8 2.1e-26 92.0 0.1 2.1 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DUF2397 PF09660.10 CRK08261.1 - 0.0011 17.9 0.6 0.0019 17.2 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2397) DUF4337 PF14235.6 CRK08261.1 - 0.48 10.5 4.7 1.2 9.3 4.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF2362 PF10154.9 CRK08261.1 - 0.54 9.1 7.4 0.75 8.7 7.4 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) Cys_Met_Meta_PP PF01053.20 CRK08319.1 - 4.1e-56 190.2 0.0 4.6e-56 190.0 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Met_gamma_lyase PF06838.11 CRK08319.1 - 0.0062 15.1 0.0 0.0063 15.1 0.0 1.1 1 0 0 1 1 1 1 Methionine gamma-lyase DUF543 PF04418.12 CRK08411.1 - 1.4e-20 73.0 1.1 1.6e-20 72.9 1.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Ribosomal_L30 PF00327.20 CRK08415.1 - 5.1e-16 58.3 2.4 5.1e-16 58.3 2.4 1.6 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.12 CRK08415.1 - 4e-15 55.8 8.0 7.5e-15 54.9 8.0 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Alpha-amylase PF00128.24 CRK08696.1 - 4.2e-19 69.3 0.2 4.5e-19 69.2 0.2 1.0 1 0 0 1 1 1 1 Alpha amylase, catalytic domain NAD_binding_9 PF13454.6 CRK08717.1 - 0.00054 20.0 0.1 0.00064 19.7 0.1 1.1 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 CRK08717.1 - 0.004 16.4 0.0 0.004 16.4 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CRK08717.1 - 0.099 11.7 0.0 0.11 11.6 0.0 1.0 1 0 0 1 1 1 0 Lycopene cyclase protein Helicase_C PF00271.31 CRK08719.1 - 1.1e-09 38.6 0.0 2e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Zn_Tnp_IS1 PF03811.13 CRK08719.1 - 0.81 9.5 5.4 0.18 11.6 0.6 2.3 3 0 0 3 3 3 0 InsA N-terminal domain CDRT4 PF15213.6 CRK08788.1 - 0.073 13.7 0.1 0.21 12.2 0.1 1.7 2 0 0 2 2 2 0 CMT1A duplicated region transcript 4 protein DUF3108 PF11306.8 CRK08791.1 - 0.092 12.7 0.0 0.19 11.7 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3108) rve PF00665.26 CRK08796.1 - 0.0063 16.7 0.0 0.017 15.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Retrotran_gag_2 PF14223.6 CRK08796.1 - 0.011 15.4 1.0 0.023 14.4 1.0 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.6 CRK08796.1 - 0.028 14.3 0.1 0.065 13.1 0.1 1.5 1 0 0 1 1 1 0 GAG-pre-integrase domain PrmA PF06325.13 CRK08796.1 - 0.037 13.4 0.2 0.077 12.4 0.2 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) BLI1 PF17324.2 CRK08796.1 - 0.083 13.6 2.2 0.12 13.0 0.6 2.0 2 0 0 2 2 2 0 BLOC-1 interactor 1 Zn_clus PF00172.18 CRK08814.1 - 0.0059 16.7 2.2 0.012 15.7 2.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Metallophos PF00149.28 CRK08819.1 - 0.0058 17.1 0.3 0.27 11.7 0.3 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CRK08819.1 - 0.0062 16.7 0.0 0.01 16.0 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Herpes_UL25 PF01499.16 CRK08825.1 - 0.00064 18.4 1.1 0.00075 18.1 1.1 1.1 1 0 0 1 1 1 1 Herpesvirus UL25 family YscO PF07321.12 CRK08825.1 - 0.01 15.8 6.8 0.01 15.8 6.8 1.6 2 0 0 2 2 2 0 Type III secretion protein YscO DUF2852 PF11014.8 CRK08825.1 - 0.029 14.5 1.2 0.05 13.8 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) SAT PF16073.5 CRK08825.1 - 0.059 13.1 0.0 0.079 12.7 0.0 1.3 1 0 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis bZIP_2 PF07716.15 CRK08825.1 - 0.098 12.8 1.0 0.098 12.8 1.0 3.4 2 1 2 4 4 4 0 Basic region leucine zipper ZapB PF06005.12 CRK08825.1 - 0.53 10.8 7.9 0.087 13.3 3.9 1.8 2 0 0 2 2 2 0 Cell division protein ZapB Metal_resist PF13801.6 CRK08825.1 - 3 8.1 13.5 0.12 12.6 6.5 1.9 2 0 0 2 2 2 0 Heavy-metal resistance Glycos_trans_3N PF02885.17 CRK08840.1 - 0.0052 16.6 0.8 1.3 8.9 0.1 2.4 2 0 0 2 2 2 2 Glycosyl transferase family, helical bundle domain Zn_clus PF00172.18 CRK08846.1 - 1.9e-08 34.3 10.2 4.8e-08 33.0 10.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-H2C2_5 PF13909.6 CRK08846.1 - 0.076 12.8 0.1 0.21 11.3 0.1 1.8 1 0 0 1 1 1 0 C2H2-type zinc-finger domain zf-BED PF02892.15 CRK08846.1 - 0.37 10.9 3.3 0.36 10.9 0.4 2.4 2 0 0 2 2 2 0 BED zinc finger zf-C2H2 PF00096.26 CRK08846.1 - 0.91 10.1 8.5 0.25 11.9 0.4 3.6 3 1 0 3 3 3 0 Zinc finger, C2H2 type DUF3723 PF12520.8 CRK08850.1 - 1.9e-06 26.9 0.0 2.2e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3723) Med15_fungi PF05397.12 CRK08860.1 - 0.2 11.9 0.1 0.29 11.4 0.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 15 cEGF PF12662.7 CRK08863.1 - 0.063 13.2 0.1 0.19 11.7 0.1 1.8 1 0 0 1 1 1 0 Complement Clr-like EGF-like hEGF PF12661.7 CRK08863.1 - 0.45 11.2 5.6 0.17 12.6 0.8 2.9 2 0 0 2 2 2 0 Human growth factor-like EGF DUF1192 PF06698.11 CRK08870.1 - 0.027 14.5 0.6 0.043 13.9 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Ank_2 PF12796.7 CRK08875.1 - 7e-11 42.6 1.0 1.9e-05 25.1 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CRK08875.1 - 1.3e-07 31.7 1.5 0.13 12.6 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CRK08875.1 - 2.8e-07 30.3 3.8 0.087 13.4 0.0 6.3 6 0 0 6 6 6 1 Ankyrin repeat Ank PF00023.30 CRK08875.1 - 5.2e-07 29.8 4.0 0.025 15.0 0.0 5.0 4 1 0 4 4 4 2 Ankyrin repeat Lipocalin_3 PF12702.7 CRK08881.1 - 0.12 12.4 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Lipocalin-like Melibiase_C PF17801.1 CRK08881.1 - 0.13 12.4 0.1 0.27 11.3 0.0 1.5 2 0 0 2 2 2 0 Alpha galactosidase C-terminal beta sandwich domain BRCT PF00533.26 CRK08889.1 - 3.4e-10 40.2 0.0 0.00071 19.9 0.0 2.3 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 CRK08889.1 - 2.5e-07 31.0 0.1 0.011 16.1 0.0 2.2 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 CRK08889.1 - 0.00064 19.6 1.7 0.0098 15.8 0.1 2.7 3 0 0 3 3 3 1 twin BRCT domain SRF-TF PF00319.18 CRK08896.1 - 8.9e-06 25.1 0.1 2.1e-05 23.9 0.1 1.6 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) BRCT PF00533.26 CRK08899.1 - 3.4e-17 62.6 2.1 2.4e-10 40.7 0.6 2.4 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 CRK08899.1 - 7.9e-17 61.0 2.0 3.8e-07 29.9 0.0 3.6 3 0 0 3 3 3 2 twin BRCT domain BRCT_2 PF16589.5 CRK08899.1 - 8e-13 48.6 2.6 1.1e-06 29.0 0.4 2.7 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain Ferric_reduct PF01794.19 CRK08899.1 - 9.9e-07 28.9 12.0 9.9e-07 28.9 12.0 3.0 2 1 0 2 2 2 1 Ferric reductase like transmembrane component LIG3_BRCT PF16759.5 CRK08899.1 - 1.5e-05 25.2 0.3 0.055 13.8 0.1 2.5 2 0 0 2 2 2 2 DNA ligase 3 BRCT domain NPR3 PF03666.13 CRK08899.1 - 1.9 7.2 19.6 0.66 8.7 6.4 2.2 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 SRF-TF PF00319.18 CRK08908.1 - 2.9e-05 23.5 0.5 4.5e-05 22.9 0.5 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF3435 PF11917.8 CRK08913.1 - 2.6e-18 66.2 1.0 2.6e-18 66.2 1.0 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF3435) zf-H2C2_2 PF13465.6 CRK08913.1 - 0.0027 18.1 11.3 0.09 13.2 0.3 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-BED PF02892.15 CRK08913.1 - 0.077 13.0 0.1 0.22 11.6 0.1 1.8 1 0 0 1 1 1 0 BED zinc finger zf-C2H2_4 PF13894.6 CRK08913.1 - 0.76 10.8 14.5 0.55 11.2 0.1 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger GFO_IDH_MocA PF01408.22 CRK08918.1 - 1.3e-17 64.7 0.0 2.2e-17 64.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 CRK08918.1 - 0.00037 20.5 0.0 0.00072 19.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Sacchrp_dh_NADP PF03435.18 CRK08918.1 - 0.053 13.8 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Trp_oprn_chp PF09534.10 CRK08928.1 - 0.15 11.9 0.2 0.73 9.6 0.1 2.0 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) FAD_binding_3 PF01494.19 CRK08932.1 - 4.1e-19 69.0 0.0 7.2e-13 48.5 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 CRK08932.1 - 4.1e-06 26.9 0.7 1.2e-05 25.4 0.5 2.0 1 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CRK08932.1 - 0.00016 21.4 1.1 0.00024 20.8 1.1 1.4 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CRK08932.1 - 0.00077 18.8 0.3 0.002 17.4 0.3 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CRK08932.1 - 0.0054 15.9 0.0 0.0078 15.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 CRK08932.1 - 0.011 14.7 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase Thi4 PF01946.17 CRK08932.1 - 0.084 12.1 0.1 0.13 11.5 0.1 1.3 1 0 0 1 1 1 0 Thi4 family ABC2_membrane PF01061.24 CRK08937.1 - 5.7e-78 261.1 62.8 1.5e-41 142.1 20.9 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 CRK08937.1 - 3e-26 92.6 0.0 6.9e-15 55.8 0.0 2.7 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 CRK08937.1 - 2.6e-24 84.9 8.1 2.9e-19 68.7 0.0 3.6 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 CRK08937.1 - 4.7e-12 46.3 0.0 2e-11 44.4 0.0 2.1 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_25 PF13481.6 CRK08937.1 - 4.9e-07 29.5 0.0 0.00041 20.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 CRK08937.1 - 1.7e-06 28.6 0.0 0.014 15.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CRK08937.1 - 1.8e-06 28.4 0.1 0.06 13.7 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.6 CRK08937.1 - 3.4e-06 27.3 0.3 0.022 14.9 0.1 2.8 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 CRK08937.1 - 5e-06 26.5 0.2 0.0038 17.1 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 CRK08937.1 - 1.8e-05 24.4 0.7 0.017 14.9 0.3 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.7 CRK08937.1 - 0.00018 20.8 42.7 0.014 14.5 17.4 2.8 2 1 1 3 3 3 2 ABC-2 family transporter protein NACHT PF05729.12 CRK08937.1 - 0.0065 16.4 0.1 3 7.7 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 CRK08937.1 - 0.0088 16.3 1.4 3.4 8.0 0.4 2.6 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 CRK08937.1 - 0.0088 16.3 2.5 1.8 8.8 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 CRK08937.1 - 0.011 16.2 0.4 3.2 8.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 CRK08937.1 - 0.012 16.0 0.1 3.4 8.1 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 CRK08937.1 - 0.014 15.1 0.1 6.4 6.5 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein cobW PF02492.19 CRK08937.1 - 0.024 14.2 3.0 1.8 8.1 0.3 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.6 CRK08937.1 - 0.084 12.7 0.0 2.2 8.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Rad17 PF03215.15 CRK08937.1 - 0.097 12.6 0.0 2.3 8.1 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_30 PF13604.6 CRK08937.1 - 0.11 12.2 1.8 9.1 5.9 0.9 2.3 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 CRK08937.1 - 0.18 11.9 0.8 22 5.2 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase PDR_assoc PF08370.11 CRK08937.1 - 0.22 11.3 6.2 0.73 9.6 0.0 3.3 3 0 0 3 3 2 0 Plant PDR ABC transporter associated AAA_24 PF13479.6 CRK08937.1 - 0.25 11.1 0.3 6.5 6.4 0.1 2.4 2 0 0 2 2 2 0 AAA domain NAD_binding_10 PF13460.6 CRK08944.1 - 2e-08 34.4 0.0 3.5e-08 33.5 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding GMC_oxred_N PF00732.19 CRK08947.1 - 2.3e-70 237.3 0.0 3.4e-70 236.8 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CRK08947.1 - 5.4e-34 117.8 0.0 1.1e-33 116.7 0.0 1.6 1 1 0 1 1 1 1 GMC oxidoreductase DUF1593 PF07632.11 CRK08952.1 - 3.3e-128 426.5 0.0 1.9e-88 296.2 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1593) REJ PF02010.15 CRK08952.1 - 4.2e-09 35.7 0.0 0.0011 17.9 0.0 2.2 2 0 0 2 2 2 2 REJ domain V-set PF07686.17 CRK08952.1 - 0.0004 20.5 0.2 0.29 11.3 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin V-set domain ig PF00047.25 CRK08952.1 - 0.0014 18.7 0.1 1.7 8.8 0.0 2.5 2 0 0 2 2 2 2 Immunoglobulin domain RabGGT_insert PF07711.11 CRK08952.1 - 0.0023 18.4 0.4 0.96 10.0 0.1 2.5 2 0 0 2 2 2 1 Rab geranylgeranyl transferase alpha-subunit, insert domain Svf1 PF08622.10 CRK08952.1 - 0.038 14.0 0.1 11 6.0 0.0 2.3 2 0 0 2 2 2 0 Svf1-like N-terminal lipocalin domain DUF5110 PF17137.4 CRK08952.1 - 0.076 13.3 0.2 27 5.1 0.0 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF5110) DUF3458 PF11940.8 CRK08952.1 - 0.11 13.0 0.5 3.3 8.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3458) Ig-like fold PapC_C PF13953.6 CRK08952.1 - 0.17 11.7 0.0 36 4.3 0.0 2.7 2 0 0 2 2 2 0 PapC C-terminal domain Aerolysin PF01117.20 CRK08952.1 - 0.21 10.8 1.2 5.8 6.0 0.1 2.2 2 0 0 2 2 2 0 Aerolysin toxin Kinin PF08260.11 CRK08952.1 - 6.6 7.6 7.3 13 6.8 1.6 2.9 2 0 0 2 2 2 0 Insect kinin peptide Sugar_tr PF00083.24 CRK08958.1 - 1.9e-23 83.1 13.1 2.2e-23 82.8 13.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK08958.1 - 2.7e-11 43.0 31.6 1.1e-07 31.1 2.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 CRK08958.1 - 0.0078 14.8 8.0 0.028 13.0 7.9 1.8 1 1 0 1 1 1 1 MFS/sugar transport protein Zn_clus PF00172.18 CRK08964.1 - 9.7e-05 22.4 6.8 0.00018 21.6 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 CRK08964.1 - 9.7e-05 21.5 0.1 0.00015 20.9 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain SH3_1 PF00018.28 CRK08968.1 - 4.6e-06 26.1 0.3 1.1e-05 25.0 0.0 1.8 2 0 0 2 2 2 1 SH3 domain SH3_16 PF18348.1 CRK08968.1 - 0.077 12.8 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial dipeptidyl-peptidase Sh3 domain SH3_9 PF14604.6 CRK08968.1 - 0.093 12.6 0.1 0.37 10.7 0.0 2.1 2 0 0 2 2 2 0 Variant SH3 domain Sclerostin PF05463.11 CRK08968.1 - 0.22 11.2 0.0 0.22 11.2 0.0 2.7 3 0 0 3 3 3 0 Sclerostin (SOST) PRA-PH PF01503.17 CRK08968.1 - 2.3 8.7 5.3 86 3.7 0.1 3.9 3 0 0 3 3 3 0 Phosphoribosyl-ATP pyrophosphohydrolase AMP-binding PF00501.28 CRK08974.1 - 1.8e-45 155.3 0.0 2.7e-45 154.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 CRK08974.1 - 1.9e-08 34.1 2.2 2.1e-08 33.9 0.3 2.0 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 CRK08974.1 - 7.1e-07 30.1 0.8 1.7e-06 28.9 0.3 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Aminotran_1_2 PF00155.21 CRK08977.1 - 1.3e-57 195.6 0.0 1.9e-57 195.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 CRK08977.1 - 0.045 13.0 0.0 0.071 12.4 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Aldedh PF00171.22 CRK08980.1 - 1.4e-42 145.8 0.4 1.8e-42 145.4 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GMC_oxred_N PF00732.19 CRK08984.1 - 5.2e-40 137.7 0.0 2.1e-19 70.0 0.0 2.2 1 1 1 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 CRK08984.1 - 1.8e-38 132.3 0.0 2.8e-38 131.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 CRK08984.1 - 6e-06 25.6 0.0 9.1e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 CRK08984.1 - 2.9e-05 24.2 0.1 0.0002 21.5 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CRK08984.1 - 8.4e-05 22.3 0.8 0.0011 18.7 0.1 2.7 3 1 1 4 4 4 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CRK08984.1 - 0.00089 18.4 0.3 0.053 12.6 0.1 2.3 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 CRK08984.1 - 0.0043 16.3 0.0 0.012 14.8 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 CRK08984.1 - 0.0063 15.4 0.0 0.012 14.5 0.0 1.4 1 0 0 1 1 1 1 Tryptophan halogenase Pkinase PF00069.25 CRK09144.1 - 1e-38 133.2 0.0 1.1e-38 133.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK09144.1 - 5.5e-20 71.7 0.0 6.1e-20 71.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CRK09144.1 - 0.0007 19.0 0.2 0.00091 18.6 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CRK09144.1 - 0.0024 17.2 0.0 0.0033 16.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CRK09144.1 - 0.0064 15.5 0.0 0.0081 15.1 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CRK09144.1 - 0.0068 16.4 0.0 0.0071 16.3 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 CRK09144.1 - 0.019 14.1 0.0 0.024 13.7 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 CRK09144.1 - 0.068 11.9 0.0 0.07 11.9 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase YukC PF10140.9 CRK09144.1 - 0.069 12.0 0.0 0.073 11.9 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC FTA2 PF13095.6 CRK09144.1 - 0.16 11.6 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 AA_permease_2 PF13520.6 CRK09284.1 - 8.9e-16 57.7 13.8 9.8e-16 57.6 13.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CRK09284.1 - 0.00011 21.0 12.9 0.00012 20.8 12.9 1.0 1 0 0 1 1 1 1 Amino acid permease Trp_Tyr_perm PF03222.13 CRK09284.1 - 0.2 10.6 7.7 0.21 10.6 7.7 1.1 1 0 0 1 1 1 0 Tryptophan/tyrosine permease family RNA_pol_Rpb2_6 PF00562.28 CRK09383.1 - 7.6e-22 77.9 0.0 8.5e-22 77.8 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 MFS_1 PF07690.16 CRK09386.1 - 3.7e-30 105.1 41.3 3.4e-23 82.1 25.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DctQ PF04290.12 CRK09386.1 - 0.24 11.3 6.2 0.69 9.8 0.5 3.1 3 0 0 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component Methyltransf_16 PF10294.9 CRK09390.1 - 1.7e-12 47.4 0.0 1e-06 28.6 0.0 2.2 2 0 0 2 2 2 2 Lysine methyltransferase Methyltransf_12 PF08242.12 CRK09390.1 - 0.033 14.9 0.0 0.12 13.2 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 CRK09390.1 - 0.14 12.9 0.0 0.43 11.3 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain DUF3446 PF11928.8 CRK09390.1 - 0.15 12.4 11.9 0.41 11.0 11.9 1.8 1 0 0 1 1 1 0 Early growth response N-terminal domain IMUP PF15761.5 CRK09390.1 - 5.1 7.8 13.2 2 9.2 6.0 2.4 2 0 0 2 2 2 0 Immortalisation up-regulated protein Glyco_tranf_2_3 PF13641.6 CRK09393.1 - 2.6e-22 79.9 0.0 4.8e-22 79.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 CRK09393.1 - 7.7e-17 61.9 0.4 7.7e-17 61.9 0.4 2.5 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 CRK09393.1 - 6.5e-15 55.4 0.0 1.1e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Cellulose_synt PF03552.14 CRK09393.1 - 6.6e-15 54.7 3.8 1.1e-09 37.4 0.1 3.6 2 1 2 4 4 4 3 Cellulose synthase Glyco_transf_21 PF13506.6 CRK09393.1 - 1.2e-12 47.6 0.0 2e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Chitin_synth_2 PF03142.15 CRK09393.1 - 0.0017 17.0 2.1 0.035 12.7 0.0 2.7 2 1 1 3 3 3 1 Chitin synthase Glyco_hydro_12 PF01670.16 CRK09398.1 - 1.5e-19 70.9 2.9 9.4e-19 68.2 2.9 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 12 PetL PF05115.14 CRK09398.1 - 0.11 12.5 2.5 0.24 11.4 2.5 1.4 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit VI (PetL) UQ_con PF00179.26 CRK09402.1 - 1.4e-09 37.7 0.1 2.9e-09 36.7 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme zf-C2H2_4 PF13894.6 CRK09402.1 - 5.6e-06 26.8 5.6 0.038 14.8 0.1 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 CRK09402.1 - 0.00086 19.6 7.6 0.11 13.1 0.1 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type Prok-E2_B PF14461.6 CRK09402.1 - 0.087 12.5 0.0 0.26 11.0 0.0 1.8 1 0 0 1 1 1 0 Prokaryotic E2 family B Ima1_N PF09779.9 CRK09402.1 - 0.15 12.9 0.1 2.8 8.8 0.0 2.3 2 0 0 2 2 2 0 Ima1 N-terminal domain DUF3844 PF12955.7 CRK09409.1 - 1.4e-36 124.8 2.5 2.6e-36 124.0 2.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) EGF_2 PF07974.13 CRK09409.1 - 7.2 7.1 16.2 2.3e+02 2.3 16.2 2.8 1 1 0 1 1 1 0 EGF-like domain hNIFK_binding PF12196.8 CRK09412.1 - 1.8 8.1 9.3 4.1 7.0 0.4 4.0 4 0 0 4 4 4 0 FHA Ki67 binding domain of hNIFK Amino_oxidase PF01593.24 CRK09416.1 - 3.5e-46 158.4 0.6 9.9e-46 156.9 0.6 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase LSM PF01423.22 CRK09416.1 - 2.5e-19 68.7 0.6 4.7e-19 67.8 0.6 1.5 1 0 0 1 1 1 1 LSM domain Putative_G5P PF17426.2 CRK09416.1 - 0.097 12.8 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative Gamma DNA binding protein G5P Globin PF00042.22 CRK09420.1 - 1.1e-07 32.3 0.0 1.4e-06 28.8 0.0 2.5 3 0 0 3 3 3 1 Globin NAD_binding_1 PF00175.21 CRK09420.1 - 2.7e-05 24.7 0.0 6.4e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Protoglobin PF11563.8 CRK09420.1 - 0.0084 16.0 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 Protoglobin FAD_binding_6 PF00970.24 CRK09420.1 - 0.065 13.6 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Amidohydro_1 PF01979.20 CRK09423.1 - 4e-53 180.9 0.0 4.7e-53 180.7 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 CRK09423.1 - 1e-13 51.6 6.1 1.1e-11 44.9 1.8 2.6 2 1 0 2 2 2 2 Amidohydrolase family DUF1039 PF06287.11 CRK09423.1 - 0.11 13.0 0.1 0.32 11.4 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1039) ADH_zinc_N_2 PF13602.6 CRK09425.1 - 0.11 13.5 0.0 0.25 12.4 0.0 1.3 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Ras PF00071.22 CRK09428.1 - 1.2e-40 138.7 0.0 2.2e-40 137.9 0.0 1.4 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CRK09428.1 - 9e-29 100.1 0.0 2.5e-28 98.7 0.0 1.8 2 0 0 2 2 1 1 Ras of Complex, Roc, domain of DAPkinase Mannosidase_ig PF17786.1 CRK09428.1 - 2.3e-13 50.5 0.2 8.2e-13 48.8 0.2 2.0 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 CRK09428.1 - 7e-12 46.0 0.1 7e-12 46.0 0.1 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Arf PF00025.21 CRK09428.1 - 2.7e-09 36.7 0.0 7.4e-09 35.3 0.0 1.6 2 0 0 2 2 2 1 ADP-ribosylation factor family Glyco_hydro_2_N PF02837.18 CRK09428.1 - 5e-05 23.3 0.0 0.00011 22.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain MMR_HSR1 PF01926.23 CRK09428.1 - 0.0041 17.2 0.0 0.0081 16.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CRK09428.1 - 0.0059 16.0 0.0 0.009 15.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Glyco_hydro_2_C PF02836.17 CRK09428.1 - 0.0061 15.7 0.4 0.027 13.6 0.4 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain PduV-EutP PF10662.9 CRK09428.1 - 0.038 13.7 0.0 1.4 8.6 0.0 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 CRK09428.1 - 0.067 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_33 PF13671.6 CRK09428.1 - 0.079 13.1 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Ig_mannosidase PF17753.1 CRK09428.1 - 0.1 12.4 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 Ig-fold domain NACHT PF05729.12 CRK09428.1 - 0.12 12.2 0.0 0.51 10.2 0.0 1.9 2 0 0 2 2 2 0 NACHT domain ABC_tran PF00005.27 CRK09428.1 - 0.16 12.5 0.0 0.45 11.0 0.0 1.7 1 0 0 1 1 1 0 ABC transporter adh_short PF00106.25 CRK09431.1 - 6.3e-33 113.9 0.0 7.6e-33 113.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK09431.1 - 2.5e-29 102.5 0.2 2.9e-29 102.3 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK09431.1 - 2.5e-09 37.3 0.2 5.3e-09 36.2 0.2 1.6 1 1 0 1 1 1 1 KR domain FLgD_tudor PF13861.6 CRK09431.1 - 0.046 14.0 0.0 0.14 12.4 0.0 1.9 2 1 0 2 2 2 0 FlgD Tudor-like domain 2-Hacid_dh_C PF02826.19 CRK09433.1 - 8.2e-45 152.3 0.2 6.2e-44 149.5 0.2 2.0 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 CRK09433.1 - 0.0022 17.6 0.2 0.045 13.3 0.0 2.5 2 1 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain AdoHcyase_NAD PF00670.21 CRK09433.1 - 0.009 16.1 0.2 0.11 12.6 0.2 2.1 1 1 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain PTR2 PF00854.21 CRK09436.1 - 7.9e-72 242.3 9.8 1.2e-71 241.7 9.8 1.2 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 CRK09436.1 - 1.9e-05 23.8 20.9 1.9e-05 23.8 20.9 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily FMO-like PF00743.19 CRK09439.1 - 5.7e-12 44.8 0.0 8.3e-12 44.3 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 CRK09439.1 - 1.1e-05 24.9 0.1 0.00049 19.4 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CRK09439.1 - 0.00027 20.3 0.0 0.00081 18.7 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CRK09439.1 - 0.0012 18.1 0.0 0.13 11.5 0.0 2.3 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.6 CRK09439.1 - 0.0021 17.3 0.0 0.014 14.5 0.0 2.1 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 CRK09439.1 - 0.0095 16.1 0.5 0.95 9.7 0.7 2.9 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CRK09439.1 - 0.022 13.8 1.1 2.4 7.2 0.3 2.8 2 1 1 3 3 3 0 FAD binding domain GIDA PF01134.22 CRK09439.1 - 0.043 12.9 0.0 5.9 5.9 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A DAO PF01266.24 CRK09439.1 - 1.1 8.8 7.0 21 4.6 0.7 3.6 2 2 1 3 3 3 0 FAD dependent oxidoreductase Glyco_hydro_43 PF04616.14 CRK09442.1 - 1.9e-67 227.6 2.3 3e-67 226.9 2.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 CRK09442.1 - 5.7e-12 45.8 0.0 1.3e-11 44.7 0.0 1.5 2 0 0 2 2 2 1 Beta xylosidase C-terminal Concanavalin A-like domain Dabb PF07876.12 CRK09449.1 - 4.3e-24 85.0 0.0 5.2e-24 84.7 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Isochorismatase PF00857.20 CRK09452.1 - 7.3e-56 189.1 9.8 1.3e-23 84.0 0.2 3.4 3 1 0 3 3 3 3 Isochorismatase family DUF2717 PF10911.8 CRK09452.1 - 0.00022 20.9 0.0 12 5.6 0.0 3.3 3 0 0 3 3 3 3 Protein of unknown function (DUF2717) DUF3880 PF12996.7 CRK09452.1 - 0.012 15.7 0.0 53 4.0 0.0 3.6 3 0 0 3 3 3 0 DUF based on E. rectale Gene description (DUF3880) DUF2284 PF10050.9 CRK09452.1 - 0.013 15.3 7.0 1.7 8.3 0.2 3.1 3 0 0 3 3 3 0 Predicted metal-binding protein (DUF2284) MOSP_C PF02722.15 CRK09452.1 - 0.041 13.6 0.0 2.5 7.7 0.0 2.1 2 0 0 2 2 2 0 Major Outer Sheath Protein C-terminal domain FAD_oxidored PF12831.7 CRK09452.1 - 0.073 12.4 2.8 19 4.4 0.1 3.1 3 0 0 3 3 3 0 FAD dependent oxidoreductase Cas_Csa4 PF09703.10 CRK09452.1 - 0.096 12.0 0.3 40 3.4 0.0 3.0 3 0 0 3 3 3 0 CRISPR-associated protein (Cas_Csa4) SARA PF11409.8 CRK09452.1 - 0.4 10.9 2.9 20 5.5 0.2 2.4 2 0 0 2 2 2 0 Smad anchor for receptor activation (SARA) AAA_11 PF13086.6 CRK09452.1 - 1.2 8.8 4.2 44 3.7 0.1 3.0 3 0 0 3 3 3 0 AAA domain zf-C3Hc3H PF13891.6 CRK09452.1 - 1.3 9.4 6.8 15 6.1 0.2 3.0 3 0 0 3 3 3 0 Potential DNA-binding domain HMG-CoA_red PF00368.18 CRK09455.1 - 2.8e-59 201.0 0.1 4e-59 200.5 0.1 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.6 CRK09455.1 - 2.1e-52 177.1 3.5 3.8e-52 176.3 3.5 1.4 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.8 CRK09455.1 - 6.5e-06 26.1 0.5 1.5e-05 24.9 0.5 1.6 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Lig_chan PF00060.26 CRK09455.1 - 0.081 12.8 5.4 0.52 10.1 0.0 2.8 2 1 0 2 2 2 0 Ligand-gated ion channel WSN PF02206.18 CRK09458.1 - 0.0037 17.1 8.6 12 5.9 0.0 6.0 7 0 0 7 7 7 2 Domain of unknown function RBD PF02196.15 CRK09458.1 - 0.084 13.0 0.2 2.2e+02 2.0 0.0 5.0 6 0 0 6 6 6 0 Raf-like Ras-binding domain Mac PF12464.8 CRK09458.1 - 3.6 7.9 14.3 2e+02 2.3 0.0 7.0 8 0 0 8 8 8 0 Maltose acetyltransferase HMG-CoA_red PF00368.18 CRK09462.1 - 1.6e-174 580.2 21.4 4.9e-124 414.1 8.1 2.2 2 0 0 2 2 2 2 Hydroxymethylglutaryl-coenzyme A reductase Esterase_phd PF10503.9 CRK09462.1 - 1.7e-25 89.8 0.9 1.7e-25 89.8 0.9 2.5 3 0 0 3 3 3 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 CRK09462.1 - 7.5e-08 32.1 0.3 2.2e-07 30.6 0.3 1.8 1 0 0 1 1 1 1 Prolyl oligopeptidase family Lyase_8_C PF02884.17 CRK09462.1 - 0.0098 16.3 1.7 7.2 7.2 0.1 2.9 3 0 0 3 3 3 2 Polysaccharide lyase family 8, C-terminal beta-sandwich domain Abhydrolase_3 PF07859.13 CRK09462.1 - 0.046 13.6 0.2 0.1 12.4 0.2 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.20 CRK09462.1 - 0.11 12.1 0.6 0.23 11.0 0.6 1.5 1 0 0 1 1 1 0 Putative esterase Peptidase_S15 PF02129.18 CRK09462.1 - 0.27 10.8 2.2 0.48 10.0 2.2 1.4 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF3565 PF12088.8 CRK09462.1 - 0.32 11.0 0.6 31 4.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3565) Sirohm_synth_M PF14824.6 CRK09462.1 - 5 6.7 6.4 23 4.5 0.4 2.9 3 0 0 3 3 3 0 Sirohaem biosynthesis protein central Mac PF12464.8 CRK09465.1 - 0.0023 18.1 5.2 57 4.1 0.0 5.8 6 0 0 6 6 6 0 Maltose acetyltransferase RBD PF02196.15 CRK09465.1 - 0.016 15.3 0.4 1.7e+02 2.4 0.0 4.9 6 0 0 6 6 6 0 Raf-like Ras-binding domain WSN PF02206.18 CRK09465.1 - 0.021 14.7 3.0 58 3.7 0.0 4.7 5 0 0 5 5 5 0 Domain of unknown function PPK2 PF03976.14 CRK09465.1 - 0.094 12.2 0.0 18 4.7 0.0 2.5 2 0 0 2 2 2 0 Polyphosphate kinase 2 (PPK2) RIG-I_C PF18119.1 CRK09465.1 - 0.29 11.1 0.8 2e+02 2.0 0.0 4.3 6 0 0 6 6 6 0 RIG-I receptor C-terminal domain ISG65-75 PF11727.8 CRK09465.1 - 0.31 10.2 2.5 0.53 9.5 2.5 1.3 1 0 0 1 1 1 0 Invariant surface glycoprotein Abi_C PF14355.6 CRK09465.1 - 0.9 9.7 6.1 72 3.6 0.0 5.4 6 0 0 6 6 6 0 Abortive infection C-terminus ATG_C PF09333.11 CRK09465.1 - 1.4 9.3 3.5 12 6.4 0.1 3.1 2 1 1 3 3 3 0 Autophagy-related protein C terminal domain Senescence PF06911.12 CRK09465.1 - 5 7.4 14.5 1.5 9.1 4.4 2.5 2 0 0 2 2 2 0 Senescence-associated protein Esterase_phd PF10503.9 CRK09468.1 - 3.2e-25 88.9 0.9 5e-25 88.3 0.9 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase CBM_1 PF00734.18 CRK09468.1 - 6.2e-12 45.3 17.3 6.2e-12 45.3 17.3 2.7 3 0 0 3 3 3 1 Fungal cellulose binding domain Peptidase_S9 PF00326.21 CRK09468.1 - 3.7e-08 33.1 0.3 5.2e-08 32.6 0.3 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 CRK09468.1 - 0.0047 16.6 3.1 0.0071 16.0 3.1 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.13 CRK09468.1 - 0.02 14.7 0.1 0.036 13.9 0.1 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.20 CRK09468.1 - 0.068 12.8 0.5 0.11 12.1 0.5 1.4 1 0 0 1 1 1 0 Putative esterase Glyco_hydro_11 PF00457.17 CRK09471.1 - 1.9e-79 265.5 14.0 2.9e-79 264.8 14.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 CBM_1 PF00734.18 CRK09471.1 - 4.2e-10 39.4 18.5 4.2e-10 39.4 18.5 2.5 2 0 0 2 2 2 1 Fungal cellulose binding domain CFEM PF05730.11 CRK09476.1 - 2.4e-14 53.2 15.4 3.9e-14 52.5 15.4 1.3 1 0 0 1 1 1 1 CFEM domain AA_permease_2 PF13520.6 CRK09479.1 - 9.9e-55 186.1 47.9 1.3e-54 185.7 47.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CRK09479.1 - 7.5e-18 64.4 43.9 1.2e-16 60.4 43.9 2.0 1 1 0 1 1 1 1 Amino acid permease DUF4554 PF15091.6 CRK09479.1 - 0.25 10.2 0.0 0.43 9.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) Glyco_hydro_11 PF00457.17 CRK09482.1 - 1.5e-79 265.8 14.9 2.3e-79 265.1 14.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 CBM_1 PF00734.18 CRK09482.1 - 4.2e-10 39.4 18.5 4.2e-10 39.4 18.5 2.4 2 0 0 2 2 2 1 Fungal cellulose binding domain CFEM PF05730.11 CRK09486.1 - 2.5e-14 53.1 15.6 4.3e-14 52.3 15.6 1.4 1 0 0 1 1 1 1 CFEM domain AA_permease_2 PF13520.6 CRK09489.1 - 6.9e-58 196.5 46.2 8.4e-58 196.2 46.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CRK09489.1 - 8.1e-22 77.4 38.7 1.1e-21 77.0 38.7 1.1 1 0 0 1 1 1 1 Amino acid permease ComP_DUS PF16732.5 CRK09493.1 - 0.069 14.0 0.2 0.14 13.0 0.2 1.6 1 0 0 1 1 1 0 Type IV minor pilin ComP, DNA uptake sequence receptor Hexokinase_2 PF03727.16 CRK09496.1 - 1.3e-65 221.1 0.0 1e-63 215.0 0.0 2.2 1 1 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 CRK09496.1 - 5.9e-64 215.6 0.1 1e-63 214.9 0.1 1.4 1 0 0 1 1 1 1 Hexokinase Zn_clus PF00172.18 CRK09499.1 - 5.3e-07 29.7 9.1 8.5e-07 29.0 9.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glucosamine_iso PF01182.20 CRK09504.1 - 1.4e-22 80.7 0.0 1.8e-22 80.3 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase FAD_binding_8 PF08022.12 CRK09504.1 - 0.029 14.5 0.0 0.06 13.4 0.0 1.5 1 0 0 1 1 1 0 FAD-binding domain Sugar-bind PF04198.13 CRK09504.1 - 0.066 12.3 0.1 0.11 11.6 0.1 1.3 1 0 0 1 1 1 0 Putative sugar-binding domain Gly-zipper_YMGG PF13441.6 CRK09508.1 - 2.9 7.7 8.7 6.3 6.6 7.7 1.8 1 1 1 2 2 2 0 YMGG-like Gly-zipper AAA_12 PF13087.6 CRK09510.1 - 1.5e-16 60.6 0.0 2.4e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CRK09510.1 - 1.6e-09 38.0 0.0 8.3e-06 25.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 CRK09510.1 - 0.015 15.0 0.1 1.6 8.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain Bunya_G2 PF03563.13 CRK09510.1 - 0.062 12.6 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 Pectate_lyase PF03211.13 CRK09514.1 - 4e-85 284.5 10.7 4.9e-85 284.2 10.7 1.1 1 0 0 1 1 1 1 Pectate lyase Globin PF00042.22 CRK09517.1 - 7e-07 29.8 0.0 1.5e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 Globin FAD_binding_6 PF00970.24 CRK09517.1 - 1.6e-05 25.2 0.0 3.2e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 CRK09517.1 - 6.8e-05 23.5 0.0 0.00019 22.0 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Protoglobin PF11563.8 CRK09517.1 - 0.0089 15.9 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 Protoglobin Amino_oxidase PF01593.24 CRK09519.1 - 2.5e-51 175.4 0.0 3.2e-51 175.1 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CRK09519.1 - 1.8e-07 31.3 0.4 1.3e-06 28.5 0.0 2.7 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CRK09519.1 - 0.0022 17.6 0.0 0.011 15.3 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Putative_G5P PF17426.2 CRK09519.1 - 0.07 13.2 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Putative Gamma DNA binding protein G5P FAD_binding_3 PF01494.19 CRK09519.1 - 0.095 11.9 0.4 0.16 11.2 0.4 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 CRK09519.1 - 0.12 11.0 0.2 0.2 10.3 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein LSM PF01423.22 CRK09522.1 - 5.6e-21 74.0 0.6 6.4e-21 73.8 0.6 1.0 1 0 0 1 1 1 1 LSM domain hNIFK_binding PF12196.8 CRK09527.1 - 5.1 6.7 11.1 5.5 6.6 0.5 4.0 4 0 0 4 4 4 0 FHA Ki67 binding domain of hNIFK DUF3844 PF12955.7 CRK09531.1 - 5.1e-37 126.2 2.3 8.8e-37 125.4 2.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) EGF_2 PF07974.13 CRK09531.1 - 3.7 8.0 15.6 1.8e+02 2.6 15.6 2.8 1 1 0 1 1 1 0 EGF-like domain UQ_con PF00179.26 CRK09534.1 - 8.5e-09 35.2 0.0 2e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme F-box-like PF12937.7 CRK09534.1 - 0.006 16.5 0.2 3.1 7.8 0.0 3.0 2 0 0 2 2 2 2 F-box-like RWD PF05773.22 CRK09534.1 - 0.052 13.8 0.1 0.13 12.6 0.1 1.7 1 0 0 1 1 1 0 RWD domain SPAM PF02090.15 CRK09534.1 - 0.12 12.2 0.3 0.28 11.0 0.3 1.5 1 0 0 1 1 1 0 Salmonella surface presentation of antigen gene type M protein zf-C2H2_4 PF13894.6 CRK09541.1 - 2e-07 31.3 2.0 0.012 16.4 0.1 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 CRK09541.1 - 6.4e-06 26.3 2.8 0.034 14.6 0.1 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type Glyco_hydro_12 PF01670.16 CRK09544.1 - 2e-17 63.9 1.6 2.5e-17 63.6 1.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 PetL PF05115.14 CRK09544.1 - 0.11 12.5 2.5 0.22 11.5 2.5 1.4 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit VI (PetL) Glyco_tranf_2_3 PF13641.6 CRK09548.1 - 2.5e-22 79.9 0.0 5.1e-22 78.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 CRK09548.1 - 8.4e-17 61.7 0.4 8.4e-17 61.7 0.4 2.6 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 CRK09548.1 - 6.8e-15 55.3 0.0 1.1e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Cellulose_synt PF03552.14 CRK09548.1 - 8.6e-15 54.3 3.5 2.1e-09 36.5 0.1 3.7 2 1 2 4 4 4 2 Cellulose synthase Glyco_transf_21 PF13506.6 CRK09548.1 - 1.3e-12 47.6 0.0 2.1e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Chitin_synth_2 PF03142.15 CRK09548.1 - 0.0092 14.6 3.5 0.047 12.3 0.0 2.6 3 0 0 3 3 3 1 Chitin synthase Methyltransf_16 PF10294.9 CRK09551.1 - 5.3e-12 45.8 0.0 3.8e-11 43.0 0.0 1.9 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_12 PF08242.12 CRK09551.1 - 0.17 12.6 0.0 0.44 11.3 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain MFS_1 PF07690.16 CRK09553.1 - 4.7e-30 104.7 39.3 1.6e-23 83.2 26.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DctQ PF04290.12 CRK09553.1 - 0.16 11.9 8.0 0.71 9.8 0.6 2.9 3 0 0 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component Cerato-platanin PF07249.12 CRK09557.1 - 1.2e-57 193.1 2.8 1.5e-57 192.9 2.8 1.1 1 0 0 1 1 1 1 Cerato-platanin DUF2760 PF10816.8 CRK09557.1 - 0.049 13.5 0.0 0.07 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2760) Sugar_tr PF00083.24 CRK09560.1 - 3.3e-101 339.4 15.7 3.7e-101 339.2 15.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK09560.1 - 2.6e-12 46.3 35.5 2.9e-09 36.3 12.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 CRK09560.1 - 0.11 10.8 3.0 2.2 6.5 3.0 2.3 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Cerato-platanin PF07249.12 CRK09564.1 - 2.2e-57 192.3 1.5 2.6e-57 192.1 1.5 1.1 1 0 0 1 1 1 1 Cerato-platanin Sugar_tr PF00083.24 CRK09566.1 - 1.1e-119 400.3 21.4 1.3e-119 400.1 21.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK09566.1 - 8.6e-21 74.2 42.9 3.3e-18 65.7 19.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 CRK09573.1 - 5e-07 29.0 0.0 8.1e-07 28.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK09573.1 - 0.00039 20.5 6.9 0.00075 19.6 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2OG-FeII_Oxy PF03171.20 CRK09577.1 - 7.4e-21 74.5 0.0 1.2e-20 73.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 CRK09577.1 - 2.8e-20 73.2 0.0 4.6e-20 72.5 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Transp_cyt_pur PF02133.15 CRK09579.1 - 4.7e-85 286.0 26.1 5.3e-85 285.8 26.1 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin 2-Hacid_dh_C PF02826.19 CRK09584.1 - 3e-45 153.8 0.0 5.3e-45 153.0 0.0 1.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CRK09584.1 - 0.0001 22.0 0.0 0.00018 21.1 0.0 1.6 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.21 CRK09584.1 - 0.0035 17.4 0.0 0.13 12.3 0.0 2.2 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_7 PF13241.6 CRK09584.1 - 0.017 15.5 0.0 0.076 13.5 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding ELFV_dehydrog PF00208.21 CRK09584.1 - 0.16 11.7 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase CytB6-F_Fe-S PF08802.10 CRK09585.1 - 0.12 12.4 4.8 63 3.7 0.0 4.7 4 1 0 4 4 4 0 Cytochrome B6-F complex Fe-S subunit Collagen_mid PF15984.5 CRK09585.1 - 0.21 11.3 10.7 55 3.4 0.1 4.3 1 1 1 2 2 2 0 Bacterial collagen, middle region AbiJ_NTD5 PF18865.1 CRK09586.1 - 0.14 11.9 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 AbiJ N-terminal domain 5 CorA PF01544.18 CRK09588.1 - 7.3e-11 41.9 0.7 7.3e-11 41.9 0.7 1.9 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Lactamase_B PF00753.27 CRK09589.1 - 1.6e-13 51.1 0.5 2e-13 50.8 0.5 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CRK09589.1 - 0.019 14.5 0.0 0.029 13.9 0.0 1.5 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Cellulase PF00150.18 CRK09590.1 - 6.7e-52 176.6 2.5 8.7e-52 176.3 2.5 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 CRK09590.1 - 3.5e-12 46.0 14.9 3.5e-12 46.0 14.9 2.4 2 0 0 2 2 2 1 Fungal cellulose binding domain Toxin_7 PF05980.12 CRK09590.1 - 0.0072 16.5 3.1 0.019 15.2 3.1 1.7 1 0 0 1 1 1 1 Toxin 7 Peptidase_M14 PF00246.24 CRK09591.1 - 2.1e-46 159.0 0.2 2.6e-46 158.8 0.2 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Anoctamin PF04547.12 CRK09592.1 - 1.2e-104 350.7 3.6 1.5e-104 350.4 3.6 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel YitT_membrane PF02588.15 CRK09592.1 - 4.3 6.6 5.7 1.1 8.6 1.6 2.0 2 0 0 2 2 2 0 Uncharacterised 5xTM membrane BCR, YitT family COG1284 DUF883 PF05957.13 CRK09594.1 - 1 10.0 21.6 4.6 7.9 2.3 4.5 1 1 4 5 5 5 0 Bacterial protein of unknown function (DUF883) CFEM PF05730.11 CRK09598.1 - 1.8e-27 95.2 47.3 4.5e-10 39.5 13.8 3.4 3 0 0 3 3 3 3 CFEM domain adh_short_C2 PF13561.6 CRK09601.1 - 1.8e-61 207.7 1.5 2.1e-61 207.5 1.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRK09601.1 - 1.2e-39 135.8 1.2 1.4e-39 135.6 1.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CRK09601.1 - 4.6e-15 56.0 0.4 6.6e-15 55.5 0.4 1.2 1 0 0 1 1 1 1 KR domain Glyco_hydro_99 PF16317.5 CRK09601.1 - 0.017 14.2 0.0 0.027 13.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 99 Amidase PF01425.21 CRK09604.1 - 9.1e-31 107.3 3.3 1.8e-30 106.3 1.9 1.8 2 0 0 2 2 2 1 Amidase PX PF00787.24 CRK09609.1 - 0.007 16.3 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 PX domain KxDL PF10241.9 CRK09609.1 - 0.012 15.9 1.4 0.023 14.9 1.4 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein DUF2183 PF09949.9 CRK09616.1 - 1.7e-26 92.4 0.0 4.4e-26 91.1 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) AMP-binding PF00501.28 CRK09618.1 - 1.1e-39 136.3 0.0 7.1e-12 44.6 0.0 4.9 4 1 1 5 5 5 4 AMP-binding enzyme DMAP_binding PF06464.11 CRK09618.1 - 7.3e-11 42.9 0.0 1.9e-10 41.5 0.0 1.7 1 0 0 1 1 1 1 DMAP1-binding Domain GvpG PF05120.12 CRK09618.1 - 0.0073 16.3 1.0 0.018 15.1 1.0 1.6 1 0 0 1 1 1 1 Gas vesicle protein G SYF2 PF08231.12 CRK09622.1 - 1.3 9.4 11.5 1.1 9.6 4.5 2.3 1 1 0 2 2 2 0 SYF2 splicing factor PDEase_II PF02112.15 CRK09624.1 - 3e-50 171.3 0.0 3.4e-22 79.0 0.0 3.3 3 1 0 3 3 3 3 cAMP phosphodiesterases class-II Lactamase_B PF00753.27 CRK09624.1 - 0.034 14.2 0.0 0.074 13.1 0.0 1.7 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily bZIP_C PF12498.8 CRK09624.1 - 0.65 11.0 3.2 1.5 9.8 3.2 1.6 1 0 0 1 1 1 0 Basic leucine-zipper C terminal DUF4045 PF13254.6 CRK09627.1 - 5.7e-91 306.2 42.9 1.6e-54 186.1 30.7 6.4 3 3 3 6 6 6 2 Domain of unknown function (DUF4045) Arf PF00025.21 CRK09627.1 - 2.3e-54 183.5 0.3 3.9e-54 182.7 0.3 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CRK09627.1 - 8.1e-11 42.2 0.1 1.5e-10 41.4 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 CRK09627.1 - 4.3e-10 39.3 0.8 9.7e-06 25.0 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gelsolin PF00626.22 CRK09627.1 - 6.2e-09 35.6 0.0 0.017 15.0 0.0 3.7 3 0 0 3 3 3 2 Gelsolin repeat Ras PF00071.22 CRK09627.1 - 1.6e-08 34.3 0.0 2.6e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 CRK09627.1 - 2.7e-08 33.4 0.0 4.2e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CRK09627.1 - 1e-06 28.8 0.0 2e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 CRK09627.1 - 7.2e-06 25.6 0.0 1.4e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 CRK09635.1 - 7.6e-59 198.1 0.0 1.4e-58 197.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF3336 PF11815.8 CRK09635.1 - 1.1e-53 180.6 1.9 2.4e-53 179.5 1.9 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) DnaJ PF00226.31 CRK09635.1 - 1.6e-16 60.2 0.7 5.2e-16 58.5 0.7 2.0 1 0 0 1 1 1 1 DnaJ domain Patatin PF01734.22 CRK09635.1 - 2.4e-10 40.9 0.1 7.3e-10 39.4 0.1 1.9 1 0 0 1 1 1 1 Patatin-like phospholipase G-alpha PF00503.20 CRK09635.1 - 3.2e-08 33.1 0.0 1.1e-05 24.7 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Sec63 PF02889.16 CRK09635.1 - 3.7e-08 32.9 0.0 0.0031 16.7 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain MMR_HSR1 PF01926.23 CRK09635.1 - 3e-06 27.3 0.0 2e-05 24.6 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 CRK09635.1 - 5.7e-06 26.6 0.0 1.7e-05 25.0 0.0 1.9 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CRK09635.1 - 6e-06 26.0 0.0 1.4e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 CRK09635.1 - 7.1e-06 25.6 0.0 1.4e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CRK09635.1 - 0.00033 20.1 0.0 0.00061 19.2 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF3325 PF11804.8 CRK09635.1 - 0.47 10.6 2.9 24 5.1 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3325) ATP-synt_DE_N PF02823.16 CRK09643.1 - 3.1e-17 62.2 0.0 4.7e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Flavin_Reduct PF01613.18 CRK09653.1 - 5.9e-15 55.6 0.0 1.1e-14 54.7 0.0 1.4 1 0 0 1 1 1 1 Flavin reductase like domain Pkinase PF00069.25 CRK09653.1 - 4.3e-05 23.0 0.0 6.4e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Mtc PF03820.17 CRK09658.1 - 4e-114 380.9 0.0 4.5e-114 380.7 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier Lactamase_B_4 PF13691.6 CRK09662.1 - 1.1e-22 79.4 0.0 2.3e-22 78.5 0.0 1.5 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 CRK09662.1 - 1.6e-18 67.0 0.1 4.3e-18 65.6 0.1 1.8 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 CRK09662.1 - 0.012 15.6 0.0 0.038 14.0 0.0 1.8 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily DnaJ PF00226.31 CRK09665.1 - 1.1e-09 38.2 0.6 2.3e-09 37.2 0.0 1.8 2 0 0 2 2 2 1 DnaJ domain DUF572 PF04502.13 CRK09665.1 - 4 7.0 20.6 4.3 6.9 20.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) GCV_T PF01571.21 CRK09667.1 - 1.8e-05 24.2 0.0 2.7e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain BUD22 PF09073.10 CRK09670.1 - 0.013 14.8 19.4 0.016 14.5 19.4 1.2 1 0 0 1 1 1 0 BUD22 DEAD PF00270.29 CRK09672.1 - 1.7e-42 145.2 0.0 2.6e-41 141.3 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CRK09672.1 - 6.7e-30 103.7 0.1 1.7e-29 102.4 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CRK09672.1 - 4.5e-06 26.8 0.0 1.2e-05 25.4 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 CRK09672.1 - 0.0078 15.0 0.0 0.01 14.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.6 CRK09672.1 - 0.013 15.8 0.1 0.93 9.8 0.0 2.6 2 1 0 2 2 2 0 AAA domain SASRP1 PF15160.6 CRK09672.1 - 0.61 9.7 2.7 1.1 8.9 2.7 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated serine-rich protein 1 Nop14 PF04147.12 CRK09672.1 - 1.5 6.9 11.8 2.2 6.4 11.8 1.1 1 0 0 1 1 1 0 Nop14-like family Pkinase PF00069.25 CRK09675.1 - 6.9e-47 160.0 0.0 1e-43 149.6 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CRK09675.1 - 7.5e-23 81.1 0.0 1.3e-21 77.1 0.0 2.1 1 1 1 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CRK09675.1 - 8.8e-06 25.2 0.0 1.4e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CRK09675.1 - 0.001 17.9 0.0 0.0015 17.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 CRK09675.1 - 0.048 13.3 0.0 5.2 6.6 0.0 2.1 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 TruD PF01142.18 CRK09678.1 - 2.6e-60 204.4 1.1 5.3e-56 190.2 0.0 2.9 3 0 0 3 3 3 2 tRNA pseudouridine synthase D (TruD) Sugar_tr PF00083.24 CRK09681.1 - 1.7e-85 287.6 18.9 2.1e-85 287.3 18.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK09681.1 - 3.7e-30 105.0 21.3 5.3e-30 104.5 21.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Folate_carrier PF01770.18 CRK09681.1 - 0.0034 16.2 0.4 1.2 7.8 0.1 2.2 2 0 0 2 2 2 2 Reduced folate carrier Phage_holin_3_2 PF04550.12 CRK09681.1 - 0.021 15.3 0.8 0.07 13.7 0.8 1.8 1 0 0 1 1 1 0 Phage holin family 2 DIOX_N PF14226.6 CRK09684.1 - 3.1e-27 95.7 0.0 4.6e-27 95.1 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 CRK09684.1 - 5.3e-19 68.6 0.0 8.5e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Amidohydro_2 PF04909.14 CRK09688.1 - 2.8e-29 102.8 2.5 4.9e-29 102.0 2.5 1.4 1 1 0 1 1 1 1 Amidohydrolase HET PF06985.11 CRK09690.1 - 5.9e-11 42.9 8.7 6.3e-09 36.3 1.9 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Abhydrolase_6 PF12697.7 CRK09693.1 - 0.00049 20.8 0.0 0.00071 20.2 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 CRK09693.1 - 0.00078 19.2 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 CRK09693.1 - 0.026 13.8 0.0 0.053 12.8 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF676 PF05057.14 CRK09693.1 - 0.032 13.7 0.0 0.049 13.1 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_2 PF02230.16 CRK09693.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase PTPLA PF04387.14 CRK09696.1 - 2.9e-55 186.5 13.8 4.5e-55 185.8 13.8 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Zn_clus PF00172.18 CRK09699.1 - 1.1e-05 25.4 9.8 1.1e-05 25.4 9.8 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 CRK09699.1 - 0.0017 18.7 1.4 0.0044 17.4 1.4 1.8 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CRK09699.1 - 0.036 14.9 0.9 0.13 13.2 0.9 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CRK09699.1 - 0.37 11.3 2.0 0.4 11.2 0.2 2.0 2 0 0 2 2 2 0 Zinc-finger double domain Aldedh PF00171.22 CRK09703.1 - 3.2e-14 52.3 0.1 5.5e-12 44.9 0.2 2.9 2 1 0 2 2 2 2 Aldehyde dehydrogenase family Cupin_2 PF07883.11 CRK09710.1 - 4.2e-07 29.6 0.0 7.5e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 CRK09710.1 - 0.004 16.8 0.0 0.026 14.2 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF861) Cupin_1 PF00190.22 CRK09710.1 - 0.059 13.0 0.0 0.093 12.3 0.0 1.3 1 0 0 1 1 1 0 Cupin AA_permease_2 PF13520.6 CRK09713.1 - 2e-87 293.8 37.0 2.7e-87 293.3 37.0 1.2 1 0 0 1 1 1 1 Amino acid permease p450 PF00067.22 CRK09713.1 - 5.5e-50 170.5 0.0 8.2e-50 169.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AA_permease PF00324.21 CRK09713.1 - 1.1e-18 67.2 31.1 1.6e-18 66.6 31.1 1.2 1 0 0 1 1 1 1 Amino acid permease Nucleos_tra2_C PF07662.13 CRK09713.1 - 2.1 8.1 6.7 1.3 8.8 0.4 3.0 2 1 1 3 3 3 0 Na+ dependent nucleoside transporter C-terminus KRE1 PF17056.5 CRK09716.1 - 0.015 15.0 1.9 0.36 10.6 0.1 2.5 2 0 0 2 2 2 0 Killer toxin-resistance protein 1 4HB_MCP_1 PF12729.7 CRK09716.1 - 0.06 12.9 0.0 0.095 12.2 0.0 1.2 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction PIG-P PF08510.12 CRK09721.1 - 3.5 7.6 15.2 0.34 10.8 8.5 2.4 2 0 0 2 2 2 0 PIG-P Pectinesterase PF01095.19 CRK09724.1 - 4e-30 104.5 1.1 4.7e-30 104.3 1.1 1.1 1 0 0 1 1 1 1 Pectinesterase Pox_MCEL PF03291.16 CRK09727.1 - 1.1e-71 241.7 0.0 2.4e-48 165.0 0.0 2.3 2 0 0 2 2 2 2 mRNA capping enzyme Methyltransf_25 PF13649.6 CRK09727.1 - 1.2e-10 42.0 0.0 5.1e-05 23.9 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 CRK09727.1 - 4.8e-09 36.8 0.0 0.0029 18.3 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 CRK09727.1 - 1.6e-06 28.7 0.1 0.11 13.1 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 CRK09727.1 - 1.9e-05 24.5 0.0 0.0025 17.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CRK09727.1 - 2.5e-05 24.2 0.0 4.5e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 CRK09727.1 - 4.8e-05 22.7 0.0 7.8e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_4 PF02390.17 CRK09727.1 - 0.11 12.0 0.0 0.77 9.2 0.0 2.0 2 0 0 2 2 2 0 Putative methyltransferase CCD48 PF15799.5 CRK09727.1 - 0.58 8.4 4.8 0.89 7.8 4.8 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 RPN7 PF10602.9 CRK09729.1 - 4.7e-54 182.7 1.1 5.5e-54 182.5 0.3 1.5 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.27 CRK09729.1 - 4.4e-15 56.1 0.0 9.3e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 PCI domain PCI PF01399.27 CRK09733.1 - 1.1e-09 38.7 0.0 2e-09 37.9 0.0 1.4 2 0 0 2 2 2 1 PCI domain Aminotran_1_2 PF00155.21 CRK09734.1 - 3.6e-36 125.1 0.0 5.3e-36 124.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Ribosomal_L33 PF00471.20 CRK09735.1 - 7.1e-05 23.2 0.0 9.5e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L33 TetR_C_4 PF08359.11 CRK09736.1 - 0.43 10.7 4.8 0.093 12.9 0.5 2.2 2 0 0 2 2 2 0 YsiA-like protein, C-terminal region DUF3091 PF11291.8 CRK09736.1 - 1 9.5 6.5 0.27 11.4 0.8 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3091) DUF948 PF06103.11 CRK09736.1 - 1.7 9.0 25.3 0.55 10.5 2.6 4.7 4 1 1 5 5 5 0 Bacterial protein of unknown function (DUF948) DUF2371 PF10177.9 CRK09738.1 - 0.051 13.7 0.0 0.067 13.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) DUF4381 PF14316.6 CRK09738.1 - 0.11 12.7 0.0 0.14 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) LapA_dom PF06305.11 CRK09738.1 - 0.51 10.2 1.8 0.84 9.5 1.8 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain NUC153 PF08159.12 CRK09739.1 - 2.9e-07 30.2 0.3 5.9e-07 29.2 0.3 1.5 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 CRK09739.1 - 3.4e-05 24.5 0.1 0.74 10.8 0.0 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat Med13_C PF06333.12 CRK09740.1 - 7.3e-94 314.7 2.2 7.3e-94 314.7 2.2 3.4 4 1 1 5 5 5 1 Mediator complex subunit 13 C-terminal domain Med13_N PF11597.8 CRK09740.1 - 7e-30 104.5 0.2 1.6e-29 103.3 0.2 1.6 1 0 0 1 1 1 1 Mediator complex subunit 13 N-terminal MID_MedPIWI PF18296.1 CRK09740.1 - 1.5e-10 41.3 0.4 6e-05 23.0 0.0 3.0 2 1 1 3 3 3 2 MID domain of medPIWI DUF3147 PF11345.8 CRK09742.1 - 0.015 15.7 0.9 0.015 15.7 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3147) Glutaredoxin PF00462.24 CRK09747.1 - 6.8e-15 55.0 0.0 1.1e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Chitin_synth_1 PF01644.17 CRK09753.1 - 2.2e-73 245.6 0.2 3.4e-73 245.0 0.2 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 CRK09753.1 - 3.9e-29 100.4 0.0 8.1e-29 99.4 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 CRK09753.1 - 1.4e-21 76.7 1.5 1.5e-17 63.5 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Sec1 PF00995.23 CRK09756.1 - 1.1e-113 381.5 0.0 1.4e-113 381.2 0.0 1.1 1 0 0 1 1 1 1 Sec1 family zf-CCCH_4 PF18044.1 CRK09759.1 - 1.7e-06 27.7 2.4 2.7e-06 27.0 2.4 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CRK09759.1 - 3.7e-06 26.8 5.9 6.5e-06 26.0 5.9 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 CRK09759.1 - 7.7e-05 22.5 2.5 0.00014 21.7 2.5 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 CRK09759.1 - 0.0018 18.5 0.2 0.0053 16.9 0.2 1.8 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 CRK09759.1 - 0.044 14.3 1.4 0.081 13.4 1.4 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Torus PF16131.5 CRK09759.1 - 0.07 13.8 0.2 0.07 13.8 0.2 3.2 2 0 0 2 2 2 0 Torus domain DUF3455 PF11937.8 CRK09764.1 - 5.6e-26 91.8 0.1 7.4e-26 91.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) LMWPc PF01451.21 CRK09769.1 - 2.5e-40 138.1 0.0 2.9e-40 137.9 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase CFEM PF05730.11 CRK09772.1 - 1.1e-11 44.7 11.4 2.1e-11 43.7 11.4 1.5 1 0 0 1 1 1 1 CFEM domain Defensin_2 PF01097.18 CRK09772.1 - 0.05 13.5 0.3 0.11 12.5 0.3 1.5 1 0 0 1 1 1 0 Arthropod defensin Gamma-thionin PF00304.20 CRK09772.1 - 0.3 11.4 7.7 0.13 12.5 1.2 2.5 2 1 0 2 2 2 0 Gamma-thionin family SOG2 PF10428.9 CRK09772.1 - 1.2 8.2 13.0 1.4 8.0 13.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Tmemb_cc2 PF10267.9 CRK09772.1 - 7 5.7 5.0 7.4 5.6 5.0 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein PCRF PF03462.18 CRK09775.1 - 4.1e-48 163.8 0.1 1e-47 162.6 0.0 1.7 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 CRK09775.1 - 1.3e-32 112.2 2.2 1.3e-32 112.1 0.7 1.8 2 0 0 2 2 2 1 RF-1 domain SPAM PF02090.15 CRK09775.1 - 0.015 15.1 2.1 1.2 8.9 0.0 2.4 2 0 0 2 2 2 0 Salmonella surface presentation of antigen gene type M protein DUF2849 PF11011.8 CRK09775.1 - 0.56 10.9 4.7 16 6.2 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2849) PRELI PF04707.14 CRK09777.1 - 1.1e-11 44.8 0.0 3e-08 33.6 0.0 2.3 2 0 0 2 2 2 2 PRELI-like family bPH_2 PF03703.14 CRK09777.1 - 0.16 12.2 0.1 0.5 10.6 0.0 1.9 2 0 0 2 2 2 0 Bacterial PH domain GWT1 PF06423.12 CRK09782.1 - 0.055 13.6 1.1 0.097 12.8 0.4 1.7 1 1 0 1 1 1 0 GWT1 TRP PF06011.12 CRK09785.1 - 1.2e-132 442.7 28.2 1.2e-132 442.7 28.2 1.3 2 0 0 2 2 2 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 CRK09785.1 - 3.6e-38 131.1 0.5 5.4e-38 130.5 0.5 1.3 1 0 0 1 1 1 1 ML-like domain 4HBT_2 PF13279.6 CRK09789.1 - 5.6e-08 33.3 0.1 8.5e-08 32.7 0.1 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily NmrA PF05368.13 CRK09792.1 - 2e-68 230.4 0.0 7.7e-36 123.8 0.0 2.3 2 0 0 2 2 2 2 NmrA-like family RPA43_OB PF17875.1 CRK09792.1 - 4e-35 121.1 0.1 4e-35 121.1 0.1 3.9 2 1 0 2 2 1 1 RPA43 OB domain in RNA Pol I NAD_binding_10 PF13460.6 CRK09792.1 - 1.4e-26 93.5 0.1 1.5e-15 57.6 0.0 2.7 2 1 0 2 2 2 2 NAD(P)H-binding Epimerase PF01370.21 CRK09792.1 - 1.5e-08 34.4 0.0 0.01 15.3 0.0 3.3 3 0 0 3 3 3 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CRK09792.1 - 2.7e-07 29.9 0.1 0.0031 16.6 0.0 2.3 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 CRK09792.1 - 5.6e-05 23.6 0.1 0.00061 20.2 0.0 2.6 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.18 CRK09792.1 - 0.00034 20.8 0.2 0.82 9.9 0.1 2.5 2 0 0 2 2 2 2 TrkA-N domain KR PF08659.10 CRK09792.1 - 0.00037 20.5 0.2 0.0025 17.7 0.0 2.3 2 0 0 2 2 2 1 KR domain Sacchrp_dh_NADP PF03435.18 CRK09792.1 - 0.00038 20.7 2.7 0.015 15.5 0.0 3.2 3 0 0 3 3 3 1 Saccharopine dehydrogenase NADP binding domain DXP_reductoisom PF02670.16 CRK09792.1 - 0.0016 19.2 0.2 1.8 9.3 0.0 2.8 2 0 0 2 2 2 2 1-deoxy-D-xylulose 5-phosphate reductoisomerase SHS2_Rpb7-N PF03876.17 CRK09792.1 - 0.0083 16.5 0.1 0.028 14.8 0.0 2.0 2 0 0 2 2 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Glu_dehyd_C PF16912.5 CRK09792.1 - 0.013 15.0 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus F420_oxidored PF03807.17 CRK09792.1 - 0.079 13.6 2.1 3.6 8.2 0.1 3.3 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.25 CRK09792.1 - 0.11 12.0 0.0 0.31 10.5 0.0 1.8 1 0 0 1 1 1 0 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 CRK09792.1 - 0.12 11.8 1.2 1.1 8.5 0.0 2.6 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Sugar_tr PF00083.24 CRK09796.1 - 7.1e-90 302.0 7.9 1.1e-89 301.4 7.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK09796.1 - 1.1e-26 93.6 52.7 7.9e-24 84.2 28.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Asp_Glu_race PF01177.22 CRK09799.1 - 0.0068 16.3 0.0 0.24 11.2 0.0 2.2 2 0 0 2 2 2 1 Asp/Glu/Hydantoin racemase YopE PF03545.13 CRK09799.1 - 0.085 13.0 0.1 0.19 11.9 0.1 1.6 1 0 0 1 1 1 0 Yersinia virulence determinant (YopE) Actin PF00022.19 CRK09802.1 - 1.3e-109 366.5 0.0 6.1e-109 364.3 0.0 1.8 1 1 0 1 1 1 1 Actin Pkinase PF00069.25 CRK09802.1 - 5e-64 216.2 0.0 1e-63 215.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK09802.1 - 2.2e-30 105.8 0.0 3.4e-30 105.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CRK09802.1 - 0.2 11.0 0.0 0.36 10.1 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Ribosomal_S24e PF01282.19 CRK09805.1 - 2.8e-35 120.1 0.0 5.3e-35 119.2 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein S24e Methyltransf_16 PF10294.9 CRK09808.1 - 1.4e-18 67.3 0.0 2.3e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 CRK09808.1 - 0.00019 21.3 0.0 0.00028 20.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK09808.1 - 0.0013 19.4 0.0 0.0028 18.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.12 CRK09808.1 - 0.0031 17.3 0.0 0.006 16.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF938) MTS PF05175.14 CRK09808.1 - 0.0081 15.7 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 CRK09808.1 - 0.014 15.2 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 CRK09808.1 - 0.016 15.0 0.1 0.033 14.0 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.16 CRK09808.1 - 0.019 14.7 0.0 0.03 14.1 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein PrmA PF06325.13 CRK09808.1 - 0.032 13.6 0.0 0.051 13.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 CRK09808.1 - 0.04 14.7 0.0 0.089 13.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_3 PF01596.17 CRK09808.1 - 0.17 11.0 0.0 0.3 10.2 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase Pro_isomerase PF00160.21 CRK09813.1 - 2e-33 115.9 0.0 3.4e-33 115.1 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 CRK09813.1 - 2e-13 50.0 0.0 3.7e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PMI_typeI PF01238.21 CRK09816.1 - 1.5e-125 419.3 0.0 1.8e-125 419.0 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I HpcH_HpaI PF03328.14 CRK09954.1 - 7e-28 97.3 0.0 9.7e-28 96.8 0.0 1.2 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP-utilizers_C PF02896.18 CRK09954.1 - 0.003 16.7 0.3 0.039 13.1 0.2 2.5 3 0 0 3 3 3 1 PEP-utilising enzyme, TIM barrel domain PK PF00224.21 CRK09954.1 - 0.012 14.6 1.5 0.023 13.6 1.2 1.6 1 1 1 2 2 2 0 Pyruvate kinase, barrel domain DNA_photolyase PF00875.18 CRK09954.1 - 0.14 12.2 0.0 0.22 11.5 0.0 1.2 1 0 0 1 1 1 0 DNA photolyase Fungal_trans PF04082.18 CRK09958.1 - 2.3e-07 30.1 0.0 3.6e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain HET PF06985.11 CRK09963.1 - 7.1e-12 45.9 7.6 1.2e-10 42.0 1.5 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Cyt-b5 PF00173.28 CRK09967.1 - 2e-15 56.6 0.0 3e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain SQS_PSY PF00494.19 CRK09969.1 - 2.8e-35 122.1 0.0 4.2e-35 121.5 0.0 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase Cbl_N2 PF02761.14 CRK09969.1 - 0.17 12.6 1.0 36 5.2 0.0 2.9 3 0 0 3 3 3 0 CBL proto-oncogene N-terminus, EF hand-like domain RmlD_sub_bind PF04321.17 CRK09972.1 - 3.1e-13 49.5 0.0 4.5e-13 48.9 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 CRK09972.1 - 9.5e-11 41.6 0.0 1.8e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 CRK09972.1 - 0.007 15.5 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 CRK09972.1 - 0.036 13.5 0.0 0.26 10.7 0.0 2.1 1 1 1 2 2 2 0 GDP-mannose 4,6 dehydratase DnaJ-X PF14308.6 CRK09974.1 - 1.6e-71 240.1 1.1 1.6e-71 240.1 1.1 1.7 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 CRK09974.1 - 1.7e-26 92.1 1.0 1.7e-26 92.1 1.0 1.8 2 0 0 2 2 2 1 DnaJ domain Ribonuc_red_lgC PF02867.15 CRK09974.1 - 0.035 12.7 0.0 0.064 11.8 0.0 1.3 1 0 0 1 1 1 0 Ribonucleotide reductase, barrel domain ATAD4 PF15321.6 CRK09976.1 - 0.73 11.2 2.8 1.2 10.5 0.6 2.6 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 Cyt-b5 PF00173.28 CRK09983.1 - 5e-15 55.4 0.0 7.7e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Gag_MA PF01140.19 CRK09983.1 - 0.14 11.9 0.2 0.14 11.9 0.2 2.3 2 1 1 3 3 3 0 Matrix protein (MA), p15 Mannosyl_trans PF05007.13 CRK09987.1 - 2.3e-75 253.8 10.6 3.1e-75 253.4 10.6 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) NIBRIN_BRCT_II PF16508.5 CRK09987.1 - 1.4e-38 131.9 0.1 5.8e-38 129.9 0.0 2.1 3 0 0 3 3 3 1 Second BRCT domain on Nijmegen syndrome breakage protein PIG-U PF06728.13 CRK09987.1 - 5.7e-11 42.1 11.3 2.2e-10 40.2 11.3 1.8 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U FHA PF00498.26 CRK09987.1 - 5e-07 30.0 0.0 9.1e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 FHA domain GT87 PF09594.10 CRK09987.1 - 8e-05 22.5 18.7 8e-05 22.5 18.7 2.2 2 1 0 2 2 2 1 Glycosyltransferase family 87 RTT107_BRCT_5 PF16770.5 CRK09987.1 - 0.00041 20.2 0.0 0.00092 19.1 0.0 1.5 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain Translin PF01997.16 CRK09993.1 - 1.9e-58 197.8 0.0 2.2e-58 197.6 0.0 1.0 1 0 0 1 1 1 1 Translin family CdvA PF18822.1 CRK09993.1 - 0.045 13.6 0.3 12 5.8 0.1 3.0 3 0 0 3 3 3 0 CdvA-like coiled-coil domain TMEM154 PF15102.6 CRK09998.1 - 0.00049 20.0 0.0 0.00081 19.3 0.0 1.3 1 0 0 1 1 1 1 TMEM154 protein family DUF4448 PF14610.6 CRK09998.1 - 0.017 14.9 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Herpes_gE PF02480.16 CRK09998.1 - 0.031 13.0 0.0 0.045 12.5 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E BatD PF13584.6 CRK09998.1 - 0.035 12.9 0.0 0.053 12.3 0.0 1.2 1 0 0 1 1 1 0 Oxygen tolerance DUF4381 PF14316.6 CRK09998.1 - 0.11 12.7 0.1 0.19 11.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) LapA_dom PF06305.11 CRK09998.1 - 0.24 11.2 0.1 0.42 10.4 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF2207 PF09972.9 CRK09998.1 - 0.28 9.9 0.0 0.41 9.4 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Hist_deacetyl PF00850.19 CRK10002.1 - 2.2e-81 273.7 0.0 4.6e-81 272.6 0.0 1.6 1 0 0 1 1 1 1 Histone deacetylase domain Zn_clus PF00172.18 CRK10006.1 - 1.7e-06 28.0 9.4 3.2e-06 27.2 9.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_61 PF03443.14 CRK10009.1 - 1.7e-52 178.4 0.0 3.3e-52 177.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Abhydrolase_4 PF08386.10 CRK10009.1 - 7.6e-22 77.4 0.1 2e-21 76.0 0.1 1.7 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 CRK10009.1 - 7.1e-16 58.6 0.0 3.9e-11 43.1 0.0 2.6 2 1 0 2 2 2 2 alpha/beta hydrolase fold FAD_binding_4 PF01565.23 CRK10015.1 - 9.5e-05 22.2 0.3 0.0002 21.1 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain DUF4440 PF14534.6 CRK10018.1 - 2.4e-05 24.7 0.3 3e-05 24.4 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) Glyco_hydro_28 PF00295.17 CRK10022.1 - 2.6e-42 145.1 0.0 3.8e-42 144.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Acetyltransf_14 PF03421.16 CRK10022.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 YopJ Serine/Threonine acetyltransferase Peptidase_C97 PF05903.14 CRK10025.1 - 0.00011 22.1 0.0 0.00018 21.3 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain DUF778 PF05608.12 CRK10025.1 - 0.0014 19.0 0.2 0.0036 17.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF778) DUF4105 PF13387.6 CRK10025.1 - 0.002 17.8 0.0 0.003 17.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4105) LRAT PF04970.13 CRK10025.1 - 0.053 13.8 0.1 0.16 12.3 0.1 1.8 1 1 0 1 1 1 0 Lecithin retinol acyltransferase BCAS2 PF05700.11 CRK10025.1 - 0.099 12.3 0.4 0.14 11.8 0.4 1.2 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) Glyco_hydro_28 PF00295.17 CRK10028.1 - 2.6e-45 154.9 0.0 3.6e-45 154.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Peptidase_C97 PF05903.14 CRK10032.1 - 0.00011 22.0 0.0 0.00019 21.3 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain DUF4105 PF13387.6 CRK10032.1 - 0.00074 19.2 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4105) DUF778 PF05608.12 CRK10032.1 - 0.0025 18.2 0.3 0.0053 17.1 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF778) LRAT PF04970.13 CRK10032.1 - 0.021 15.2 0.2 0.2 11.9 0.1 2.2 1 1 1 2 2 2 0 Lecithin retinol acyltransferase BCAS2 PF05700.11 CRK10032.1 - 0.16 11.7 0.5 0.27 10.9 0.5 1.3 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) CHORD PF04968.12 CRK10037.1 - 2.4 8.9 6.8 0.87 10.4 0.2 2.6 2 1 0 2 2 2 0 CHORD BTK PF00779.19 CRK10042.1 - 0.14 12.0 0.8 0.31 10.9 0.8 1.6 1 0 0 1 1 1 0 BTK motif CHORD PF04968.12 CRK10042.1 - 3.1 8.6 8.0 0.76 10.5 0.2 2.7 2 1 0 2 2 2 0 CHORD MFS_1 PF07690.16 CRK10045.1 - 6.7e-14 51.6 11.2 6.7e-14 51.6 11.2 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK10045.1 - 4.2e-08 32.5 2.2 4.2e-08 32.5 2.2 3.0 2 2 1 3 3 3 2 Sugar (and other) transporter Glyco_hydro_61 PF03443.14 CRK10047.1 - 2.1e-25 89.9 0.0 3.5e-25 89.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 MFS_1 PF07690.16 CRK10047.1 - 2.7e-12 46.3 13.2 2.7e-12 46.3 13.2 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK10047.1 - 4.3e-08 32.5 1.2 4.3e-08 32.5 1.2 2.9 2 1 1 3 3 3 1 Sugar (and other) transporter Glyco_hydro_61 PF03443.14 CRK10051.1 - 6e-101 336.6 0.3 3.4e-54 183.9 0.1 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 61 MG2 PF01835.19 CRK10051.1 - 1.9e-05 25.0 0.2 0.37 11.3 0.0 2.4 2 0 0 2 2 2 2 MG2 domain DUF4469 PF14734.6 CRK10051.1 - 0.024 14.8 0.0 13 6.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4469) with IG-like fold Phage_min_tail PF05939.13 CRK10051.1 - 0.035 14.5 0.0 15 6.0 0.0 2.3 2 0 0 2 2 2 0 Phage minor tail protein DUF3821 PF12863.7 CRK10051.1 - 0.041 13.8 0.2 16 5.3 0.0 3.0 4 0 0 4 4 4 0 Domain of unknown function (DUF3821) NAR2 PF16974.5 CRK10051.1 - 0.16 11.3 0.0 20 4.5 0.0 2.2 2 0 0 2 2 2 0 High-affinity nitrate transporter accessory Fungal_trans PF04082.18 CRK10054.1 - 2.9e-21 75.7 0.2 4.8e-21 75.0 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK10054.1 - 7.5e-09 35.6 10.9 1.8e-08 34.4 10.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_4 PF01063.19 CRK10057.1 - 1.1e-30 107.2 0.0 1.4e-30 106.8 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV MFS_1 PF07690.16 CRK10060.1 - 3.6e-31 108.4 34.4 3.6e-31 108.4 34.4 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily DSRB PF10781.9 CRK10060.1 - 0.037 13.7 0.0 0.08 12.6 0.0 1.5 1 0 0 1 1 1 0 Dextransucrase DSRB Amino_oxidase PF01593.24 CRK10063.1 - 1.4e-49 169.7 0.0 1.6e-49 169.5 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CRK10063.1 - 3.4e-12 46.4 0.1 9.1e-12 45.0 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CRK10063.1 - 1.5e-05 24.8 1.3 2.9e-05 23.8 0.6 1.8 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CRK10063.1 - 9e-05 21.8 0.1 0.00039 19.7 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CRK10063.1 - 0.00013 22.4 0.3 0.00037 21.0 0.2 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CRK10063.1 - 0.00074 18.3 0.1 0.0034 16.2 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.6 CRK10063.1 - 0.00095 19.2 0.1 0.22 11.5 0.0 2.6 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 CRK10063.1 - 0.0061 15.8 0.1 0.0099 15.1 0.1 1.2 1 0 0 1 1 1 1 Thi4 family 3HCDH_N PF02737.18 CRK10063.1 - 0.027 14.4 0.3 0.064 13.1 0.3 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 CRK10063.1 - 0.037 13.1 0.5 0.058 12.5 0.5 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.19 CRK10063.1 - 0.057 12.7 0.4 0.099 11.9 0.4 1.3 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.21 CRK10063.1 - 0.066 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 CRK10063.1 - 0.16 11.3 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase FMO-like PF00743.19 CRK10063.1 - 0.2 10.0 0.1 0.29 9.5 0.1 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like Ank_4 PF13637.6 CRK10066.1 - 1.2e-13 51.3 0.1 2.8e-08 34.1 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 CRK10066.1 - 6.9e-11 42.2 1.7 1.9e-10 40.8 0.2 2.5 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CRK10066.1 - 6.4e-10 39.5 0.0 1.7e-09 38.2 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 CRK10066.1 - 2.6e-09 37.1 0.2 0.0013 19.1 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 CRK10066.1 - 6.1e-08 32.3 0.1 0.02 15.4 0.0 4.5 4 0 0 4 4 4 1 Ankyrin repeat Helo_like_N PF17111.5 CRK10066.1 - 1.7e-05 24.3 0.3 2.9e-05 23.5 0.3 1.4 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins DUF3530 PF12048.8 CRK10066.1 - 0.002 17.6 0.0 0.0032 16.9 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3530) Toprim_3 PF13362.6 CRK10066.1 - 0.018 15.4 0.2 1 9.8 0.0 2.5 2 0 0 2 2 2 0 Toprim domain SesA PF17107.5 CRK10066.1 - 0.026 14.7 0.0 0.056 13.6 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Epimerase PF01370.21 CRK10070.1 - 6.8e-07 29.0 0.0 1.3e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 CRK10070.1 - 2.1e-06 27.8 0.0 3.3e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 CRK10070.1 - 0.00069 18.9 0.0 0.0012 18.1 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Semialdhyde_dh PF01118.24 CRK10070.1 - 0.012 16.0 0.0 0.025 15.0 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DUF3731 PF12531.8 CRK10070.1 - 0.021 14.6 0.1 0.036 13.9 0.1 1.3 1 0 0 1 1 1 0 DNA-K related protein KR PF08659.10 CRK10070.1 - 0.12 12.2 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 KR domain GMC_oxred_N PF00732.19 CRK10073.1 - 2.3e-56 191.4 0.0 7.3e-56 189.7 0.0 1.8 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CRK10073.1 - 9.3e-33 113.8 0.0 1.6e-32 113.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 CRK10073.1 - 1.4e-07 31.0 0.9 0.0011 18.1 0.5 2.1 1 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 CRK10073.1 - 3.6e-06 27.1 0.1 3.5e-05 24.0 0.1 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CRK10073.1 - 8.8e-05 22.2 0.5 0.0097 15.5 0.3 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 CRK10073.1 - 0.0003 20.1 0.7 0.11 11.7 0.2 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CRK10073.1 - 0.0015 17.6 0.1 0.0025 17.0 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Amino_oxidase PF01593.24 CRK10073.1 - 0.0069 15.7 0.0 0.052 12.8 0.0 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 CRK10073.1 - 0.052 12.3 0.0 0.09 11.5 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein TrkA_N PF02254.18 CRK10073.1 - 0.11 12.7 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Trp_halogenase PF04820.14 CRK10073.1 - 0.15 10.9 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_2 PF07992.14 CRK10073.1 - 0.16 11.1 0.2 0.48 9.6 0.1 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Haem_degrading PF03928.14 CRK10077.1 - 1.3e-29 102.6 0.2 1.8e-29 102.2 0.2 1.2 1 0 0 1 1 1 1 Haem-degrading Nucleocap_ssRNA PF11128.8 CRK10077.1 - 0.057 13.2 0.0 0.13 12.0 0.0 1.6 2 0 0 2 2 2 0 Plant viral coat protein nucleocapsid Alpha-amylase PF00128.24 CRK10081.1 - 3.5e-58 197.8 0.2 2.2e-56 191.8 0.2 2.2 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 CRK10081.1 - 0.00032 20.9 0.0 0.00092 19.4 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1966) Aminotran_5 PF00266.19 CRK10081.1 - 0.069 12.1 0.1 0.13 11.2 0.1 1.3 1 0 0 1 1 1 0 Aminotransferase class-V Abhydrolase_6 PF12697.7 CRK10084.1 - 6.4e-12 46.5 2.0 1e-11 45.9 2.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CRK10084.1 - 6.2e-09 35.9 0.1 0.01 15.5 0.1 3.4 2 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CRK10084.1 - 4.9e-06 26.0 0.1 6.9e-05 22.2 0.0 2.5 2 1 1 3 3 3 1 Serine aminopeptidase, S33 Glyco_hydro_28 PF00295.17 CRK10085.1 - 3.2e-35 121.7 1.1 4.3e-35 121.3 1.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 CRK10085.1 - 0.0091 15.9 2.2 0.0091 15.9 2.2 2.2 1 1 1 2 2 2 1 Right handed beta helix region PAP2_3 PF14378.6 CRK10086.1 - 1.8e-36 125.6 10.3 1.8e-36 125.6 10.3 1.6 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 CRK10086.1 - 0.52 10.9 0.1 0.52 10.9 0.1 2.6 3 0 0 3 3 3 0 PAP2 superfamily C-terminal DUF4470 PF14737.6 CRK10087.1 - 1.3e-08 34.9 0.0 3.7e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TPR_MalT PF17874.1 CRK10087.1 - 1.2e-05 24.8 0.2 2.3e-05 24.0 0.2 1.3 1 0 0 1 1 1 1 MalT-like TPR region TPR_12 PF13424.6 CRK10087.1 - 0.0001 22.5 1.9 0.00024 21.3 1.9 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 CRK10087.1 - 0.042 14.1 1.0 0.1 12.9 1.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 CRK10087.1 - 0.046 14.5 0.7 0.046 14.5 0.7 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 CRK10087.1 - 0.12 12.6 1.0 0.31 11.3 1.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 CRK10087.1 - 0.36 10.7 1.2 0.7 9.8 1.2 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Tyrosinase PF00264.20 CRK10088.1 - 1.5e-48 166.0 0.3 2e-48 165.6 0.3 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Pyr_excise PF03013.14 CRK10088.1 - 0.19 11.7 0.0 0.4 10.7 0.0 1.4 1 0 0 1 1 1 0 Pyrimidine dimer DNA glycosylase Peptidase_S8 PF00082.22 CRK10093.1 - 1.2e-18 67.4 7.2 1.5e-18 67.1 7.2 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 CRK10093.1 - 0.085 13.5 0.0 0.14 12.8 0.0 1.5 1 1 0 1 1 1 0 Peptidase inhibitor I9 Pkinase PF00069.25 CRK10100.1 - 7.2e-46 156.7 0.6 7.7e-36 123.8 0.4 2.4 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CRK10100.1 - 3.7e-23 82.1 0.7 6.3e-23 81.4 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CRK10100.1 - 0.022 13.5 0.4 0.071 11.9 0.0 1.9 2 0 0 2 2 2 0 Fungal protein kinase Ank_2 PF12796.7 CRK10105.1 - 1.2e-70 234.1 24.5 2.6e-16 60.0 0.6 5.8 2 1 5 7 7 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CRK10105.1 - 2.2e-57 190.7 19.9 3.4e-10 40.2 0.0 9.6 1 1 9 10 10 10 9 Ankyrin repeats (many copies) Ank PF00023.30 CRK10105.1 - 7.4e-41 136.9 18.4 0.0017 18.7 0.0 11.0 10 0 0 10 10 10 9 Ankyrin repeat Ank_3 PF13606.6 CRK10105.1 - 2.1e-40 132.1 11.2 0.00057 20.1 0.0 11.0 10 0 0 10 10 10 9 Ankyrin repeat Ank_5 PF13857.6 CRK10105.1 - 7.4e-30 102.6 10.2 6.7e-05 23.1 0.1 9.3 1 1 9 10 10 10 8 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.20 CRK10105.1 - 9.4e-09 34.9 0.3 2.2e-08 33.6 0.3 1.6 1 1 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.12 CRK10105.1 - 1.7e-08 34.5 0.2 3.6e-08 33.5 0.2 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 CRK10105.1 - 5.4e-07 30.2 0.4 1.9e-06 28.4 0.4 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CRK10105.1 - 0.0039 17.5 0.1 0.013 15.8 0.1 1.9 2 0 0 2 2 1 1 AAA domain NB-ARC PF00931.22 CRK10105.1 - 0.011 15.0 0.1 0.024 13.9 0.1 1.5 1 0 0 1 1 1 0 NB-ARC domain DERM PF14704.6 CRK10105.1 - 0.13 12.7 0.1 0.33 11.4 0.1 1.6 1 0 0 1 1 1 0 Dermatopontin UDPG_MGDP_dh_C PF03720.15 CRK10105.1 - 0.14 12.6 3.4 83 3.7 0.0 5.8 6 3 0 6 6 5 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain PilO PF04350.13 CRK10105.1 - 0.18 12.0 0.0 1.2 9.2 0.0 2.1 2 0 0 2 2 2 0 Pilus assembly protein, PilO CAP59_mtransfer PF11735.8 CRK10264.1 - 7.6e-21 74.9 0.5 9.8e-21 74.5 0.5 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 MF_alpha_N PF05436.11 CRK10367.1 - 0.05 13.5 0.5 0.066 13.1 0.1 1.6 2 0 0 2 2 2 0 Mating factor alpha precursor N-terminus COA2 PF17051.5 CRK10369.1 - 9.5e-05 22.4 0.0 9.6e-05 22.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome C oxidase assembly factor 2 Alk_phosphatase PF00245.20 CRK10452.1 - 3.9e-76 256.7 0.2 5.7e-75 252.8 0.2 1.9 1 1 0 1 1 1 1 Alkaline phosphatase DUF3328 PF11807.8 CRK10458.1 - 5.8e-48 163.6 1.5 1.5e-47 162.2 1.5 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) GRP PF07172.11 CRK10461.1 - 0.0039 17.8 6.6 0.0047 17.6 6.6 1.2 1 0 0 1 1 1 1 Glycine rich protein family Glyco_hydro_10 PF00331.20 CRK10465.1 - 7.8e-99 330.8 0.1 9.2e-99 330.6 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.18 CRK10465.1 - 1.7e-13 50.2 12.5 4.8e-13 48.8 12.5 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain Mucin PF01456.17 CRK10465.1 - 0.00021 21.3 16.2 0.00036 20.6 16.2 1.4 1 0 0 1 1 1 1 Mucin-like glycoprotein Toxin_7 PF05980.12 CRK10465.1 - 0.8 10.0 2.8 1.6 9.0 2.8 1.5 1 0 0 1 1 1 0 Toxin 7 Glyco_hydro_10 PF00331.20 CRK10469.1 - 2.5e-30 105.7 0.7 3.8e-30 105.1 0.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 HLH PF00010.26 CRK10469.1 - 1.5 8.8 4.3 2.7 8.0 0.2 2.6 2 0 0 2 2 2 0 Helix-loop-helix DNA-binding domain Apt1 PF10351.9 CRK10477.1 - 0.51 9.1 7.5 0.69 8.7 7.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain MCLC PF05934.11 CRK10477.1 - 2.4 6.8 4.7 3.5 6.2 4.7 1.2 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) FixS PF03597.15 CRK10477.1 - 2.8 7.7 4.0 4.6 7.0 4.0 1.3 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type DUF908 PF06012.12 CRK10477.1 - 7.9 5.8 16.7 16 4.8 16.7 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) zf-C2H2_4 PF13894.6 CRK10482.1 - 0.037 14.9 1.9 3.1 8.9 1.0 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 CRK10482.1 - 0.11 13.2 0.0 0.31 11.7 0.0 1.8 1 0 0 1 1 1 0 Zinc finger C2H2-type, 3 repeats zf-CHY PF05495.12 CRK10482.1 - 0.14 12.7 0.9 0.3 11.6 0.9 1.4 1 0 0 1 1 1 0 CHY zinc finger zf-C2H2_11 PF16622.5 CRK10482.1 - 0.3 10.9 1.5 14 5.5 0.1 2.9 2 0 0 2 2 2 0 zinc-finger C2H2-type SKG6 PF08693.10 CRK10486.1 - 2.8e-09 36.2 0.1 4.6e-09 35.5 0.1 1.3 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Mid2 PF04478.12 CRK10486.1 - 0.024 14.5 0.0 0.039 13.8 0.0 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor MHYT PF03707.16 CRK10486.1 - 0.06 13.5 0.1 0.15 12.2 0.1 1.6 1 0 0 1 1 1 0 Bacterial signalling protein N terminal repeat DUF347 PF03988.12 CRK10486.1 - 0.06 13.5 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) Rax2 PF12768.7 CRK10486.1 - 0.065 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity PRP38_assoc PF12871.7 CRK10493.1 - 0.12 13.0 21.9 0.14 12.8 3.3 2.4 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term GLEYA PF10528.9 CRK10495.1 - 5.9e-17 61.9 0.3 1.3e-16 60.8 0.3 1.6 1 0 0 1 1 1 1 GLEYA domain PA14 PF07691.12 CRK10495.1 - 0.15 11.9 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 PA14 domain ThrE PF06738.12 CRK10496.1 - 9.1e-72 241.3 14.8 4.2e-70 235.8 3.6 3.9 3 0 0 3 3 3 2 Putative threonine/serine exporter Sugar_tr PF00083.24 CRK10496.1 - 8.1e-47 160.1 53.1 9.5e-23 80.8 6.8 4.3 5 0 0 5 5 5 3 Sugar (and other) transporter MFS_1 PF07690.16 CRK10496.1 - 1.1e-41 142.9 82.5 2.7e-21 75.9 14.0 5.0 5 1 1 6 6 6 3 Major Facilitator Superfamily ThrE_2 PF12821.7 CRK10496.1 - 7.4e-05 22.9 0.3 7.4e-05 22.9 0.3 7.5 9 0 0 9 9 9 1 Threonine/Serine exporter, ThrE DUF4564 PF15169.6 CRK10496.1 - 0.049 13.4 1.5 22 4.7 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4564) NodS PF05401.11 CRK10496.1 - 0.092 12.3 0.1 17 5.0 0.0 2.2 2 0 0 2 2 2 0 Nodulation protein S (NodS) p450 PF00067.22 CRK10497.1 - 8e-20 71.0 0.0 3.5e-19 68.9 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 DUF4287 PF14117.6 CRK10497.1 - 0.033 14.3 0.0 0.11 12.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4287) Fungal_trans_2 PF11951.8 CRK10499.1 - 4e-06 25.9 0.0 5.6e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.25 CRK10502.1 - 1.1e-17 64.1 0.9 3.7e-15 55.9 0.7 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CRK10502.1 - 2.9e-13 49.9 1.1 4.6e-10 39.5 1.1 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK10502.1 - 1.5e-10 41.3 0.6 2.4e-10 40.6 0.6 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 CRK10502.1 - 0.073 12.2 0.1 0.099 11.8 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein AMP-binding PF00501.28 CRK10506.1 - 2.2e-90 303.3 12.0 4.9e-36 124.2 0.1 5.1 2 2 1 4 4 4 4 AMP-binding enzyme AMP-binding_C PF13193.6 CRK10506.1 - 2.2e-06 28.5 0.0 5.4e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF2633 PF11119.8 CRK10506.1 - 0.0081 16.0 0.0 3.9 7.5 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2633) SIS_2 PF13580.6 CRK10506.1 - 0.035 14.1 0.1 8.1 6.5 0.0 2.4 2 0 0 2 2 2 0 SIS domain Phage_TTP_12 PF16461.5 CRK10506.1 - 0.037 13.7 0.0 8.6 6.1 0.0 2.4 2 0 0 2 2 2 0 Lambda phage tail tube protein, TTP DUF3377 PF11857.8 CRK10506.1 - 0.058 13.3 11.6 6.4 6.8 0.5 5.1 5 0 0 5 5 5 0 Domain of unknown function (DUF3377) DUF896 PF05979.12 CRK10506.1 - 0.11 12.3 0.2 7.3 6.6 0.1 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) Peptidase_U57 PF05582.12 CRK10506.1 - 0.14 11.4 0.7 12 5.0 0.1 2.3 2 0 0 2 2 2 0 YabG peptidase U57 tRNA_NucTransf2 PF09249.11 CRK10506.1 - 0.17 12.2 0.1 11 6.4 0.0 2.7 2 0 0 2 2 2 0 tRNA nucleotidyltransferase, second domain DUF4383 PF14325.6 CRK10506.1 - 0.19 12.0 9.2 1.9 8.8 1.3 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4383) Smim3 PF17307.2 CRK10506.1 - 0.28 10.7 14.9 1.5 8.3 0.4 4.8 4 0 0 4 4 4 0 Small integral membrane protein 3 TMCCDC2 PF15844.5 CRK10506.1 - 0.47 10.4 7.5 6.4 6.7 0.9 2.5 2 0 0 2 2 2 0 Transmembrane and coiled-coil domain-containing protein 2 PEN-2 PF10251.9 CRK10506.1 - 0.99 9.9 7.7 7.4 7.1 1.0 2.9 2 0 0 2 2 2 0 Presenilin enhancer-2 subunit of gamma secretase Saf_2TM PF18303.1 CRK10506.1 - 1.1 8.9 19.3 2.5 7.7 4.6 2.9 3 0 0 3 3 3 0 SAVED-fused 2TM effector domain TFR_dimer PF04253.15 CRK10511.1 - 8.7e-33 113.0 0.0 1.9e-32 111.9 0.0 1.6 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 CRK10511.1 - 1.7e-14 53.9 0.0 3.6e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 CRK10511.1 - 6.7e-11 42.1 0.0 1.4e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 PA domain DUF5069 PF16798.5 CRK10511.1 - 0.011 15.9 0.2 8.8 6.5 0.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF5069) Nicastrin PF05450.15 CRK10511.1 - 0.021 14.3 0.0 0.039 13.4 0.0 1.3 1 0 0 1 1 1 0 Nicastrin DUF2156 PF09924.9 CRK10511.1 - 0.028 13.4 0.5 0.051 12.6 0.0 1.6 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2156) DUF4834 PF16118.5 CRK10511.1 - 3.7 8.6 4.8 50 4.9 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Vps35 PF03635.17 CRK10514.1 - 0 1025.6 0.1 0 1025.4 0.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 DUF4692 PF15763.5 CRK10514.1 - 3.3 8.2 5.9 3.4 8.1 3.7 2.0 1 1 1 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) MHYT PF03707.16 CRK10520.1 - 1.6 9.0 9.6 1.5 9.0 0.3 3.3 3 0 0 3 3 3 0 Bacterial signalling protein N terminal repeat 2OG-FeII_Oxy_2 PF13532.6 CRK10525.1 - 4.5e-13 49.8 0.0 7.2e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 CRK10525.1 - 0.061 13.8 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Zn_clus PF00172.18 CRK10527.1 - 2.2e-09 37.3 11.5 3.6e-09 36.6 11.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 CRK10527.1 - 0.0023 16.8 0.2 0.0044 15.9 0.1 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain SAP18 PF06487.12 CRK10527.1 - 0.025 14.8 0.0 0.044 14.0 0.0 1.3 1 0 0 1 1 1 0 Sin3 associated polypeptide p18 (SAP18) p450 PF00067.22 CRK10530.1 - 3.8e-51 174.3 0.0 4.7e-51 174.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-C2H2_9 PF16293.5 CRK10530.1 - 0.076 12.9 0.0 1.4 8.8 0.0 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (1 copy) Pectate_lyase PF03211.13 CRK10533.1 - 1.1e-85 286.3 9.9 1.6e-85 285.8 9.9 1.2 1 0 0 1 1 1 1 Pectate lyase Pectate_lyase PF03211.13 CRK10536.1 - 9.3e-09 35.1 1.5 1.1e-08 34.8 1.5 1.1 1 0 0 1 1 1 1 Pectate lyase SET PF00856.28 CRK10538.1 - 2.5e-08 34.5 0.0 7.3e-08 33.0 0.0 1.8 1 1 0 1 1 1 1 SET domain AA_permease_2 PF13520.6 CRK10541.1 - 2.3e-32 112.4 28.8 2.7e-32 112.1 28.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CRK10541.1 - 2.8e-19 69.1 23.6 3.4e-19 68.8 23.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CRK10544.1 - 3.2e-17 62.5 21.8 3.5e-17 62.3 21.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CRK10544.1 - 1.4e-06 27.2 18.3 1.7e-06 26.9 18.3 1.0 1 0 0 1 1 1 1 Amino acid permease Pox_F16 PF04708.12 CRK10546.1 - 0.022 14.2 0.1 0.028 13.9 0.1 1.1 1 0 0 1 1 1 0 Poxvirus F16 protein SR-25 PF10500.9 CRK10548.1 - 0.016 14.9 1.8 0.017 14.7 1.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pox_F16 PF04708.12 CRK10548.1 - 0.022 14.2 0.1 0.028 13.9 0.1 1.1 1 0 0 1 1 1 0 Poxvirus F16 protein DUF746 PF05344.11 CRK10554.1 - 0.037 13.9 0.0 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 Domain of Unknown Function (DUF746) Dala_Dala_lig_C PF07478.13 CRK10557.1 - 5.2e-10 39.2 0.0 7.4e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 CRK10557.1 - 6.1e-05 23.1 0.0 9.4e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 CRK10557.1 - 0.00037 20.1 0.0 0.00081 19.0 0.0 1.6 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 CRK10557.1 - 0.00052 19.6 0.0 0.0024 17.4 0.0 1.9 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain GARS_A PF01071.19 CRK10557.1 - 0.0019 18.0 0.0 0.0027 17.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain MFS_1 PF07690.16 CRK10560.1 - 1.2e-19 70.5 12.2 1.6e-19 70.1 12.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily FMO-like PF00743.19 CRK10564.1 - 0.035 12.5 0.0 0.047 12.1 0.0 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like Aldedh PF00171.22 CRK10566.1 - 3.4e-166 553.3 0.3 4e-166 553.1 0.3 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family ADH_N PF08240.12 CRK10569.1 - 2.3e-30 104.7 0.5 3.8e-30 104.0 0.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CRK10569.1 - 3.1e-17 62.8 0.0 4.8e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CRK10569.1 - 0.0047 18.0 0.0 0.008 17.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 CRK10569.1 - 0.091 12.0 0.0 0.21 10.8 0.0 1.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain PHO4 PF01384.20 CRK10574.1 - 8.5e-105 350.5 10.8 1.2e-104 350.1 10.8 1.1 1 0 0 1 1 1 1 Phosphate transporter family AFOR_N PF02730.15 CRK10574.1 - 0.038 13.9 0.5 0.087 12.7 0.5 1.6 1 0 0 1 1 1 0 Aldehyde ferredoxin oxidoreductase, N-terminal domain ThiF PF00899.21 CRK10630.1 - 3.5e-10 39.7 0.1 3.5e-10 39.7 0.1 1.1 1 0 0 1 1 1 1 ThiF family SBDS PF01172.18 CRK10681.1 - 3.4e-36 123.2 0.3 3.9e-36 123.0 0.3 1.0 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein ketoacyl-synt PF00109.26 CRK10893.1 - 6.9e-70 235.5 0.0 2.1e-69 233.9 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 CRK10893.1 - 2e-64 218.1 2.3 3.5e-64 217.3 2.3 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 CRK10893.1 - 3.4e-44 151.3 0.0 6.9e-44 150.3 0.0 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 CRK10893.1 - 4e-39 133.3 0.0 1.3e-37 128.4 0.0 2.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 CRK10893.1 - 3.2e-37 128.2 0.0 1.4e-36 126.1 0.0 2.2 1 0 0 1 1 1 1 KR domain KAsynt_C_assoc PF16197.5 CRK10893.1 - 1.7e-19 70.3 0.0 7.4e-19 68.3 0.0 2.1 2 0 0 2 2 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N PF00107.26 CRK10893.1 - 4.4e-14 52.6 0.1 2.2e-13 50.3 0.1 2.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CRK10893.1 - 1.2e-13 52.2 0.0 6.4e-13 49.9 0.0 2.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 CRK10893.1 - 2.2e-10 40.3 0.0 2.2e-10 40.3 0.0 2.8 4 0 0 4 4 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK10893.1 - 3.7e-08 33.2 0.0 1.6e-07 31.2 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase SAT PF16073.5 CRK10893.1 - 1.6e-07 31.3 1.9 1e-06 28.7 0.9 2.6 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Sacchrp_dh_NADP PF03435.18 CRK10893.1 - 0.00012 22.3 0.1 0.059 13.6 0.0 3.3 3 0 0 3 3 2 1 Saccharopine dehydrogenase NADP binding domain ACP_syn_III PF08545.10 CRK10893.1 - 0.00015 21.6 0.1 0.00058 19.7 0.1 2.2 1 1 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.23 CRK10893.1 - 0.0023 17.3 0.7 0.0059 16.0 0.0 2.0 2 1 0 2 2 2 1 Thiolase, N-terminal domain ADH_N PF08240.12 CRK10893.1 - 0.0031 17.4 0.1 0.009 15.9 0.1 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain GDP_Man_Dehyd PF16363.5 CRK10893.1 - 0.011 15.2 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NAD_binding_3 PF03447.16 CRK10893.1 - 0.016 15.8 0.1 0.12 13.0 0.0 2.6 2 1 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 CRK10893.1 - 0.023 14.6 0.4 0.53 10.1 0.0 2.9 2 0 0 2 2 2 0 NAD(P)H-binding NmrA PF05368.13 CRK10893.1 - 0.16 11.5 2.5 0.36 10.3 0.0 2.6 3 0 0 3 3 3 0 NmrA-like family FSH1 PF03959.13 CRK10898.1 - 1.3e-26 93.6 0.0 1.7e-26 93.3 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) NAD_binding_11 PF14833.6 CRK10901.1 - 4.7e-68 227.0 1.4 2.6e-35 121.3 0.0 2.6 2 0 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 CRK10901.1 - 4.2e-63 212.2 8.3 6.4e-32 110.9 2.7 2.9 3 0 0 3 3 3 2 NAD binding domain of 6-phosphogluconate dehydrogenase SBD_N PF07005.11 CRK10901.1 - 3.2e-59 200.4 0.0 7.7e-59 199.2 0.0 1.7 1 0 0 1 1 1 1 Sugar-binding N-terminal domain NBD_C PF17042.5 CRK10901.1 - 6.1e-43 147.3 1.5 6.1e-43 147.3 1.5 2.4 3 0 0 3 3 3 1 Nucleotide-binding C-terminal domain 2-Hacid_dh_C PF02826.19 CRK10901.1 - 1.4e-07 31.1 0.0 0.00032 20.1 0.0 3.1 3 0 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 CRK10901.1 - 1.1e-06 29.1 7.5 0.00052 20.5 0.2 4.4 3 1 0 3 3 3 2 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh PF00984.19 CRK10901.1 - 6.1e-05 23.2 0.6 0.096 12.9 0.1 3.0 2 1 0 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, central domain 3HCDH_N PF02737.18 CRK10901.1 - 0.0001 22.2 5.3 0.0018 18.2 1.6 2.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 CRK10901.1 - 0.0064 16.2 0.8 0.26 10.9 0.0 2.5 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 CRK10901.1 - 0.13 11.9 4.2 52 3.4 0.4 4.3 3 1 1 4 4 4 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Zn_clus PF00172.18 CRK10904.1 - 1e-06 28.8 8.0 1.6e-06 28.1 8.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 CRK10904.1 - 1.5e-06 27.5 1.2 3.1e-06 26.4 0.1 2.1 2 1 0 2 2 2 1 Fungal specific transcription factor domain DUF4635 PF15466.6 CRK10904.1 - 0.48 9.9 4.2 1.9 8.0 1.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4635) ALMT PF11744.8 CRK10904.1 - 3.8 6.2 5.1 0.46 9.2 0.8 1.6 2 0 0 2 2 2 0 Aluminium activated malate transporter MFS_1 PF07690.16 CRK10908.1 - 7.9e-39 133.6 35.7 7.9e-39 133.6 35.7 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK10908.1 - 1.6e-09 37.2 21.4 2e-09 36.8 21.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter p450 PF00067.22 CRK10910.1 - 1.9e-33 115.9 0.0 4e-31 108.3 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Cutinase PF01083.22 CRK10912.1 - 1.9e-46 158.3 0.5 2.2e-46 158.0 0.5 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 CRK10912.1 - 0.0022 17.6 0.1 0.003 17.1 0.1 1.3 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.11 CRK10912.1 - 0.0023 17.8 0.0 0.0032 17.4 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) Lipase_3 PF01764.25 CRK10912.1 - 0.044 13.7 0.0 0.058 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF2974 PF11187.8 CRK10912.1 - 0.1 12.1 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_2 PF02230.16 CRK10912.1 - 0.21 11.4 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DIOX_N PF14226.6 CRK10913.1 - 1.2e-31 109.9 0.0 3.6e-30 105.2 0.0 2.1 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 CRK10913.1 - 7.9e-09 35.9 0.0 1.7e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GxGYxYP_C PF14323.6 CRK10913.1 - 0.069 13.0 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 GxGYxYP putative glycoside hydrolase C-terminal domain zf-met2 PF12907.7 CRK10916.1 - 2.2e-15 56.5 6.4 3.4e-15 55.9 6.4 1.3 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.14 CRK10916.1 - 9.5e-10 39.2 9.5 1.8e-09 38.3 9.5 1.4 1 0 0 1 1 1 1 4F5 protein family IF-2B PF01008.17 CRK10922.1 - 3.4e-44 151.2 0.1 1.1e-43 149.5 0.1 1.7 1 1 0 1 1 1 1 Initiation factor 2 subunit family DUF4701 PF15773.5 CRK10922.1 - 7.2 5.5 16.3 9.3 5.1 15.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4701) IF3_C PF00707.22 CRK10925.1 - 4e-06 26.7 0.1 8e-06 25.7 0.1 1.5 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.6 CRK10925.1 - 0.0046 16.7 1.0 0.0073 16.0 1.0 1.3 1 0 0 1 1 1 1 Mitochondrial translation initiation factor Peptidase_S26 PF10502.9 CRK10926.1 - 2.3e-05 24.2 0.0 0.00025 20.8 0.0 2.1 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.23 CRK10926.1 - 0.0025 17.8 0.0 0.0045 16.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Arm PF00514.23 CRK10927.1 - 4.1e-48 160.0 23.3 5.8e-13 48.4 0.3 7.5 7 1 0 7 7 7 6 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 CRK10927.1 - 1.3e-14 54.3 4.5 0.00036 21.0 0.2 5.6 5 1 0 5 5 5 3 HEAT-like repeat HEAT_2 PF13646.6 CRK10927.1 - 3.7e-11 43.3 4.2 0.00056 20.2 0.2 5.0 1 1 4 5 5 5 5 HEAT repeats HEAT PF02985.22 CRK10927.1 - 8.7e-09 34.9 8.3 0.085 13.2 0.4 5.9 6 0 0 6 6 6 3 HEAT repeat Arm_2 PF04826.13 CRK10927.1 - 2e-06 27.5 2.3 0.0068 15.9 0.2 2.7 1 1 1 2 2 2 2 Armadillo-like Adaptin_N PF01602.20 CRK10927.1 - 3.2e-05 22.7 4.1 0.00059 18.5 3.5 2.6 2 1 1 3 3 3 2 Adaptin N terminal region V-ATPase_H_N PF03224.14 CRK10927.1 - 9.1e-05 21.9 1.6 0.00043 19.7 1.0 2.0 2 0 0 2 2 2 1 V-ATPase subunit H KAP PF05804.12 CRK10927.1 - 0.00016 20.0 0.5 0.00024 19.4 0.5 1.2 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_C PF11698.8 CRK10927.1 - 0.0021 18.2 0.5 8.1 6.6 0.1 3.9 2 1 3 5 5 5 1 V-ATPase subunit H Atx10homo_assoc PF09759.9 CRK10927.1 - 0.008 16.2 1.8 2.2 8.4 0.1 3.6 2 1 2 4 4 4 1 Spinocerebellar ataxia type 10 protein domain DUF5578 PF17741.1 CRK10927.1 - 0.0096 15.4 4.0 0.19 11.1 0.5 3.5 2 1 2 4 4 4 1 Family of unknown function (DUF5578) HEAT_PBS PF03130.16 CRK10927.1 - 0.14 12.9 4.0 13 6.8 0.3 5.0 5 0 0 5 5 4 0 PBS lyase HEAT-like repeat UNC45-central PF11701.8 CRK10927.1 - 0.18 11.8 5.0 1.9 8.5 0.3 3.8 3 3 1 4 4 4 0 Myosin-binding striated muscle assembly central DUF1479 PF07350.12 CRK10929.1 - 2.1e-156 520.9 0.0 2.9e-156 520.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) HHH PF00633.23 CRK10929.1 - 0.01 15.7 0.2 0.026 14.4 0.2 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif Bap31 PF05529.12 CRK10932.1 - 1.1e-48 164.6 12.0 1.5e-48 164.1 12.0 1.2 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 CRK10932.1 - 2.1e-14 53.2 4.2 3.7e-14 52.5 4.2 1.4 1 0 0 1 1 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain TACC_C PF05010.14 CRK10932.1 - 0.0068 16.2 1.2 0.01 15.7 1.2 1.2 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Mod_r PF07200.13 CRK10932.1 - 0.011 15.8 0.5 0.019 15.0 0.5 1.3 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Wtap PF17098.5 CRK10932.1 - 0.018 15.0 0.7 0.035 14.0 0.7 1.5 1 0 0 1 1 1 0 WTAP/Mum2p family Spc7 PF08317.11 CRK10932.1 - 0.047 12.6 1.3 0.071 12.0 1.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein TolA_bind_tri PF16331.5 CRK10932.1 - 0.064 13.3 0.6 0.17 12.0 0.6 1.9 1 1 0 1 1 1 0 TolA binding protein trimerisation DUF192 PF02643.15 CRK10932.1 - 0.075 13.2 0.1 0.12 12.6 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized ACR, COG1430 Csm1_N PF18504.1 CRK10932.1 - 0.079 13.3 4.0 0.22 11.9 2.5 2.1 1 1 1 2 2 2 0 Csm1 N-terminal domain DivIC PF04977.15 CRK10932.1 - 0.08 12.7 4.3 0.53 10.1 0.4 3.1 3 1 1 4 4 4 0 Septum formation initiator UPF0242 PF06785.11 CRK10932.1 - 0.15 12.1 4.3 0.17 12.0 3.5 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus APG6_N PF17675.1 CRK10932.1 - 0.22 12.1 3.1 0.17 12.4 1.7 1.5 2 0 0 2 2 2 0 Apg6 coiled-coil region TMF_DNA_bd PF12329.8 CRK10932.1 - 1 9.4 6.5 1.6 8.8 5.8 1.7 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Peroxin-13_N PF04088.13 CRK10934.1 - 1.7e-50 171.1 0.0 2.6e-50 170.5 0.0 1.3 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.17 CRK10934.1 - 2e-08 33.8 0.0 4.5e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 CRK10934.1 - 5.5e-07 29.3 0.1 1.2e-06 28.2 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CRK10934.1 - 6.7e-07 28.8 0.0 1.4e-06 27.8 0.0 1.6 1 1 0 1 1 1 1 SH3 domain SH3_3 PF08239.11 CRK10934.1 - 0.12 12.7 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial SH3 domain TraT PF05818.12 CRK10934.1 - 7.9 6.1 8.1 15 5.1 8.1 1.6 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein DUF2401 PF10287.9 CRK10939.1 - 1.7e-91 305.9 0.0 2.7e-91 305.3 0.0 1.3 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 CRK10939.1 - 5.2e-21 74.8 0.0 1.7e-20 73.2 0.0 2.0 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) LSM PF01423.22 CRK10940.1 - 1.1e-10 41.0 0.0 1.6e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 LSM domain Pil1 PF13805.6 CRK10942.1 - 6.8e-125 415.9 0.2 9e-125 415.5 0.2 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.11 CRK10942.1 - 0.075 12.4 2.1 0.2 11.0 2.1 1.8 1 1 0 1 1 1 0 FAM92 protein APG6_N PF17675.1 CRK10942.1 - 3.1 8.3 10.3 8 7.0 1.1 3.0 1 1 0 2 2 2 0 Apg6 coiled-coil region EZH2_N PF18601.1 CRK10945.1 - 7.9e-36 122.2 3.7 1.9e-35 121.0 3.7 1.7 1 0 0 1 1 1 1 EZH2 N-terminal domain Ezh2_MCSS PF18600.1 CRK10945.1 - 5.2e-24 83.6 1.3 1e-23 82.6 1.3 1.5 1 0 0 1 1 1 1 MCSS domain SET PF00856.28 CRK10945.1 - 3.7e-15 56.7 0.3 3.7e-15 56.7 0.3 3.4 3 2 0 3 3 3 1 SET domain preSET_CXC PF18264.1 CRK10945.1 - 2e-07 31.3 15.2 2e-07 31.3 15.2 3.2 2 1 0 2 2 2 1 CXC domain DUF155 PF02582.14 CRK10948.1 - 8.7e-112 371.2 4.0 5.8e-55 186.1 0.3 2.5 2 0 0 2 2 2 2 Uncharacterised ACR, YagE family COG1723 SET PF00856.28 CRK10948.1 - 4.3e-15 56.5 0.2 4.3e-15 56.5 0.2 2.8 3 1 0 3 3 3 1 SET domain LBP_BPI_CETP_C PF02886.17 CRK10948.1 - 0.00039 20.0 0.2 0.95 8.9 0.0 2.2 2 0 0 2 2 2 2 LBP / BPI / CETP family, C-terminal domain VF530 PF09905.9 CRK10948.1 - 0.12 12.6 0.2 25 5.1 0.0 2.3 2 0 0 2 2 2 0 DNA-binding protein VF530 ECSCR PF15820.5 CRK10948.1 - 0.15 11.9 0.1 0.39 10.6 0.1 1.6 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Stap_Strp_tox_C PF02876.17 CRK10948.1 - 0.15 12.4 0.6 31 5.0 0.1 2.6 2 0 0 2 2 2 0 Staphylococcal/Streptococcal toxin, beta-grasp domain Insulin_TMD PF17870.1 CRK10948.1 - 0.82 9.8 2.0 0.56 10.3 0.2 1.7 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment E1-E2_ATPase PF00122.20 CRK10951.1 - 5.7e-52 175.9 0.4 1.5e-51 174.5 0.4 1.7 1 0 0 1 1 1 1 E1-E2 ATPase HMA PF00403.26 CRK10951.1 - 6.1e-45 151.5 0.5 2.9e-11 43.6 0.0 4.5 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.26 CRK10951.1 - 2.3e-42 145.7 1.6 5.3e-42 144.5 1.6 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CRK10951.1 - 6.1e-06 26.2 0.4 0.00034 20.5 0.2 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CRK10951.1 - 0.0097 16.3 0.0 0.022 15.1 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF1656 PF07869.12 CRK10951.1 - 0.96 9.5 5.5 1.4 9.0 2.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1656) PRA1 PF03208.19 CRK10951.1 - 9.3 5.9 7.2 1.3 8.6 2.0 2.2 2 0 0 2 2 2 0 PRA1 family protein E1-E2_ATPase PF00122.20 CRK10954.1 - 7.6e-52 175.4 0.6 2.1e-51 174.0 0.6 1.8 1 0 0 1 1 1 1 E1-E2 ATPase HMA PF00403.26 CRK10954.1 - 1.7e-45 153.2 0.4 1.5e-11 44.6 0.0 4.5 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.26 CRK10954.1 - 4.6e-41 141.4 1.3 1.1e-40 140.2 1.3 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CRK10954.1 - 7e-06 26.0 0.5 0.00036 20.4 0.2 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CRK10954.1 - 0.0047 17.4 0.0 0.011 16.1 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CRK10954.1 - 0.18 11.9 0.1 0.45 10.6 0.1 1.7 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF1656 PF07869.12 CRK10954.1 - 0.7 9.9 5.6 0.89 9.6 2.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1656) RelB_N PF18506.1 CRK10954.1 - 2 8.3 7.4 16 5.4 0.0 4.0 4 0 0 4 4 4 0 RelB Antitoxin alpha helical domain PCI PF01399.27 CRK10956.1 - 4.7e-08 33.5 0.1 7.4e-08 32.9 0.1 1.4 1 0 0 1 1 1 1 PCI domain TetR_C_34 PF17929.1 CRK10956.1 - 0.0065 16.6 1.0 1.5 8.9 0.3 2.5 1 1 1 2 2 2 2 Tetracyclin repressor-like, C-terminal domain RGS PF00615.19 CRK10958.1 - 2.1e-21 76.3 0.0 6.8e-08 32.8 0.0 3.2 3 0 0 3 3 3 3 Regulator of G protein signaling domain Cytochrom_B_C PF00032.17 CRK10958.1 - 0.0025 18.1 9.9 0.34 11.2 0.5 3.4 2 2 1 4 4 4 2 Cytochrome b(C-terminal)/b6/petD QueT PF06177.11 CRK10958.1 - 7.8 6.9 15.7 2.4 8.5 4.6 2.3 2 0 0 2 2 2 0 QueT transporter Ribosomal_L31e PF01198.19 CRK10960.1 - 6e-23 80.9 0.3 1.2e-22 80.0 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein L31e PCI PF01399.27 CRK10960.1 - 2.5e-06 27.9 0.1 3.7e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 PCI domain Ribosomal_L31e PF01198.19 CRK10962.1 - 1.6e-38 130.8 0.4 2.2e-38 130.4 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L31e UQ_con PF00179.26 CRK10963.1 - 2.3e-94 312.5 0.0 5.9e-46 155.6 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CRK10963.1 - 1.6e-11 44.1 0.0 0.00022 21.0 0.0 2.2 2 0 0 2 2 2 2 Prokaryotic E2 family B RWD PF05773.22 CRK10963.1 - 1.1e-06 28.9 0.0 0.063 13.6 0.0 2.4 2 0 0 2 2 2 2 RWD domain UEV PF05743.13 CRK10963.1 - 2.7e-05 24.0 0.0 0.29 11.0 0.0 2.4 2 0 0 2 2 2 2 UEV domain BRE PF06113.12 CRK10963.1 - 0.061 12.2 0.1 8.8 5.1 0.0 2.1 2 0 0 2 2 2 0 Brain and reproductive organ-expressed protein (BRE) Pkinase PF00069.25 CRK10967.1 - 3.2e-58 197.2 0.0 4.1e-58 196.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK10967.1 - 5e-28 98.1 0.0 7.3e-28 97.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CRK10967.1 - 1.8e-07 30.8 0.0 2.5e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CRK10967.1 - 0.00074 19.5 0.0 0.57 10.1 0.0 2.6 2 0 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 CRK10967.1 - 0.0065 15.8 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CRK10967.1 - 0.21 10.5 0.0 0.33 9.8 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Sugar_tr PF00083.24 CRK10969.1 - 1.5e-84 284.4 2.9 2.1e-84 284.0 2.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK10969.1 - 1.5e-17 63.6 8.9 2.1e-17 63.1 8.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily IBR PF01485.21 CRK10969.1 - 1e-12 48.1 34.5 5.9e-09 36.0 6.9 3.3 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 CRK10969.1 - 1e-05 25.5 7.3 1e-05 25.5 7.3 3.4 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_11 PF17123.5 CRK10969.1 - 6.1e-05 22.7 4.0 6.1e-05 22.7 4.0 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_2 PF13639.6 CRK10969.1 - 0.0001 22.6 6.3 0.0001 22.6 6.3 3.7 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 CRK10969.1 - 0.0003 20.6 6.1 0.0003 20.6 6.1 4.2 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CRK10969.1 - 0.0011 18.8 8.1 0.0011 18.8 8.1 3.7 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CRK10969.1 - 0.012 15.5 6.8 0.012 15.5 6.8 3.5 2 1 1 3 3 3 0 zinc-RING finger domain FAD_binding_2 PF00890.24 CRK10970.1 - 3.7e-84 283.2 0.9 5.3e-84 282.7 0.9 1.2 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 CRK10970.1 - 3.3e-21 75.2 0.0 3.3e-20 72.0 0.0 2.6 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 CRK10970.1 - 4.9e-14 52.7 0.3 8e-14 52.0 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 CRK10970.1 - 1.3e-09 37.9 1.2 6.2e-09 35.7 1.2 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CRK10970.1 - 6.1e-08 32.2 0.6 9.4e-07 28.3 0.3 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CRK10970.1 - 4.3e-07 30.1 3.3 1e-06 28.9 0.9 2.7 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 CRK10970.1 - 1.6e-06 27.7 0.1 2.7e-06 26.9 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 CRK10970.1 - 4.3e-05 22.4 3.0 0.012 14.4 0.6 3.3 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox_3 PF13738.6 CRK10970.1 - 6.3e-05 22.4 0.0 0.21 10.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CRK10970.1 - 0.00062 19.1 1.8 0.059 12.6 0.8 2.4 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 CRK10970.1 - 0.0072 15.4 2.5 0.13 11.3 1.2 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A Amino_oxidase PF01593.24 CRK10970.1 - 0.021 14.1 1.4 0.29 10.4 0.3 2.8 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 CRK10970.1 - 0.034 13.4 0.6 0.065 12.5 0.6 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 CRK10970.1 - 0.036 14.6 2.9 2 9.0 0.5 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Sin3a_C PF16879.5 CRK10971.1 - 1.4e-65 221.8 3.7 4.4e-65 220.2 2.4 2.3 2 0 0 2 2 2 1 C-terminal domain of Sin3a protein PAH PF02671.21 CRK10971.1 - 1.3e-39 134.1 6.7 3.9e-18 65.3 2.9 3.7 3 0 0 3 3 3 2 Paired amphipathic helix repeat Sin3_corepress PF08295.12 CRK10971.1 - 2.3e-37 127.0 0.0 5.3e-37 125.8 0.0 1.6 1 0 0 1 1 1 1 Sin3 family co-repressor TSP_NTD PF17804.1 CRK10971.1 - 0.048 13.9 1.8 0.24 11.6 0.0 2.6 2 0 0 2 2 2 0 Tail specific protease N-terminal domain PhageMin_Tail PF10145.9 CRK10971.1 - 0.051 13.4 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 Phage-related minor tail protein Nuf2 PF03800.14 CRK10971.1 - 0.12 12.5 0.4 1.9 8.6 0.0 2.8 3 0 0 3 3 3 0 Nuf2 family Fasciclin PF02469.22 CRK10971.1 - 0.15 12.3 0.0 0.34 11.1 0.0 1.5 1 0 0 1 1 1 0 Fasciclin domain Thiolase_N PF00108.23 CRK10973.1 - 1.6e-90 303.0 2.5 2.6e-90 302.3 2.5 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CRK10973.1 - 5e-46 155.4 1.7 6.6e-46 155.0 0.5 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 CRK10973.1 - 0.00011 21.9 0.7 0.00011 21.9 0.7 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 CRK10973.1 - 0.037 13.9 4.0 0.4 10.5 0.1 2.8 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GTP_EFTU PF00009.27 CRK10974.1 - 2.4e-44 151.2 0.0 3.6e-44 150.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 CRK10974.1 - 7.7e-35 120.1 4.3 1.5e-34 119.2 4.3 1.5 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 CRK10974.1 - 5.7e-24 84.2 0.0 1.4e-23 83.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 CRK10974.1 - 6e-19 67.9 0.0 1.7e-18 66.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 CRK10974.1 - 1.6e-10 41.2 0.1 1.2e-09 38.4 0.0 2.6 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.6 CRK10974.1 - 3.2e-08 33.5 0.1 5.7e-07 29.5 0.0 2.4 2 0 0 2 2 2 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 CRK10974.1 - 0.00073 19.6 0.1 0.0014 18.7 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeS_assembly_P PF01883.19 CRK10976.1 - 1.5e-06 28.3 0.0 1.8e-05 24.8 0.0 2.2 1 1 0 1 1 1 1 Iron-sulfur cluster assembly protein Fungal_trans PF04082.18 CRK10979.1 - 8.5e-11 41.4 0.0 1.3e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK10979.1 - 3.7e-07 30.2 9.3 3.7e-07 30.2 9.3 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Thioredoxin_4 PF13462.6 CRK10981.1 - 1e-09 38.8 0.0 0.00047 20.3 0.0 2.6 2 1 0 2 2 2 2 Thioredoxin Tautomerase_2 PF14552.6 CRK10981.1 - 0.00019 21.5 0.0 1.2 9.3 0.0 2.6 2 0 0 2 2 2 2 Tautomerase enzyme DSBA PF01323.20 CRK10981.1 - 0.02 14.7 0.9 8.1 6.2 0.0 3.1 2 1 1 3 3 3 0 DSBA-like thioredoxin domain Cathelicidins PF00666.17 CRK10981.1 - 0.083 13.2 0.0 23 5.4 0.0 2.4 2 0 0 2 2 2 0 Cathelicidin MatB PF16449.5 CRK10981.1 - 0.12 12.2 0.2 32 4.3 0.0 2.9 2 1 1 3 3 3 0 Fimbrillin MatB Croc_4 PF17691.1 CRK10981.1 - 0.49 10.4 5.5 0.79 9.8 5.5 1.4 1 0 0 1 1 1 0 Contingent replication of cDNA 4 FRG1 PF06229.12 CRK10984.1 - 1.7e-49 168.1 0.2 3.1e-49 167.3 0.2 1.3 1 0 0 1 1 1 1 FRG1-like domain Fascin PF06268.13 CRK10984.1 - 0.0008 19.6 0.0 0.0021 18.3 0.0 1.7 2 0 0 2 2 2 1 Fascin domain WD40 PF00400.32 CRK10986.1 - 1.1e-14 54.6 1.1 0.0027 18.5 0.1 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat HEM4 PF02602.15 CRK10986.1 - 0.00048 19.5 1.1 0.66 9.3 0.1 2.2 2 0 0 2 2 2 2 Uroporphyrinogen-III synthase HemD P34-Arc PF04045.14 CRK10986.1 - 0.094 12.4 0.1 11 5.7 0.0 2.1 1 1 1 2 2 2 0 Arp2/3 complex, 34 kD subunit p34-Arc DUF3546 PF12066.8 CRK10995.1 - 1.3e-31 109.1 1.2 1.9e-31 108.5 1.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3546) PEP-utilisers_N PF05524.13 CRK10995.1 - 0.031 14.4 0.6 0.04 14.1 0.6 1.3 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal Adhesin_P1_N PF18652.1 CRK10995.1 - 0.034 14.1 0.4 0.034 14.1 0.4 1.6 2 0 0 2 2 2 0 Adhesin P1 N-terminal domain DUF789 PF05623.12 CRK10995.1 - 0.31 10.7 2.3 0.34 10.5 2.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF789) Acatn PF13000.7 CRK10996.1 - 3.9e-32 111.5 0.7 1.5e-22 79.8 0.1 2.0 1 1 1 2 2 2 2 Acetyl-coenzyme A transporter 1 Trypan_PARP PF05887.11 CRK10996.1 - 0.0023 17.9 6.6 0.0035 17.3 6.6 1.2 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) BphX PF06139.12 CRK10996.1 - 0.033 14.1 0.3 0.049 13.6 0.3 1.3 1 0 0 1 1 1 0 BphX-like Glyco_hydro_75 PF07335.11 CRK11053.1 - 2.3e-64 216.6 0.9 3.2e-64 216.1 0.9 1.2 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 Ctr PF04145.15 CRK11057.1 - 3.2e-38 131.7 0.1 3.7e-38 131.4 0.1 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Phage_holin_3_6 PF07332.11 CRK11057.1 - 3.9 7.6 7.3 4.3 7.4 3.3 2.1 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Ferric_reduct PF01794.19 CRK11058.1 - 1.8e-24 86.2 8.8 1.8e-24 86.2 8.8 1.7 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 CRK11058.1 - 8.3e-15 55.2 0.0 1.3e-14 54.6 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 CRK11058.1 - 1.5e-11 44.3 0.0 3.6e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 CRK11058.1 - 1.1e-06 29.3 0.0 2.4e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DUF4428 PF14471.6 CRK11059.1 - 1.5 8.8 7.1 7.1 6.6 0.1 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4428) MFS_1 PF07690.16 CRK11060.1 - 1.3e-38 132.9 29.4 1.3e-38 132.9 29.4 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily UcrQ PF02939.16 CRK11060.1 - 0.077 12.9 0.2 0.27 11.2 0.2 2.0 1 0 0 1 1 1 0 UcrQ family GRDP-like PF07173.12 CRK11061.1 - 6.2e-15 56.1 0.0 1.4e-09 38.7 0.0 2.6 2 0 0 2 2 2 2 Glycine-rich domain-containing protein-like Sugar_tr PF00083.24 CRK11062.1 - 1.2e-135 452.9 29.2 1.4e-135 452.7 29.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK11062.1 - 2e-25 89.5 32.8 1.1e-15 57.5 14.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Trep_Strep PF09605.10 CRK11062.1 - 7.3 6.5 21.6 2.4 8.1 0.0 4.0 3 1 1 4 4 4 0 Hypothetical bacterial integral membrane protein (Trep_Strep) Pox_A14 PF05767.12 CRK11062.1 - 7.9 6.7 13.1 2.3 8.4 0.0 4.3 3 1 1 4 4 4 0 Poxvirus virion envelope protein A14 DUF374 PF04028.13 CRK11063.1 - 0.13 11.9 1.2 0.72 9.5 1.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF374) F-box-like PF12937.7 CRK11064.1 - 0.00022 21.0 2.0 0.00033 20.5 0.3 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CRK11064.1 - 0.015 15.1 1.9 0.061 13.2 0.3 2.6 3 0 0 3 3 3 0 F-box domain DUF4530 PF15039.6 CRK11065.1 - 0.19 11.9 3.9 0.24 11.6 1.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4530) GST_N_3 PF13417.6 CRK11066.1 - 1.7e-10 41.2 0.2 3.6e-10 40.1 0.2 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CRK11066.1 - 3.7e-09 36.7 0.1 9.1e-09 35.5 0.1 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 CRK11066.1 - 1.3e-07 31.8 0.0 2.4e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CRK11066.1 - 2.8e-05 24.2 0.0 5.1e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CRK11066.1 - 0.00022 21.4 0.0 0.00037 20.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CRK11066.1 - 0.0013 18.7 0.1 0.0028 17.6 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain FAA_hydrolase PF01557.18 CRK11067.1 - 1.3e-52 178.6 0.0 2.2e-52 177.9 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 CRK11067.1 - 9.8e-33 112.5 0.0 1.7e-32 111.8 0.0 1.4 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal MFS_1 PF07690.16 CRK11068.1 - 1.3e-47 162.5 68.4 3.3e-27 95.3 44.1 3.0 3 0 0 3 3 3 2 Major Facilitator Superfamily DUF1772 PF08592.11 CRK11068.1 - 0.014 15.7 9.8 6.7 7.0 0.2 4.7 3 1 0 3 3 3 0 Domain of unknown function (DUF1772) DUF4537 PF15057.6 CRK11068.1 - 0.031 14.3 0.3 11 6.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4537) DUF5367 PF17329.2 CRK11068.1 - 0.044 13.9 1.5 0.98 9.6 0.7 3.5 2 0 0 2 2 2 0 Family of unknown function (DUF5367) Orf78 PF06024.12 CRK11068.1 - 0.049 13.9 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Orf78 (ac78) DUF2929 PF11151.8 CRK11068.1 - 0.26 11.6 5.4 18 5.7 0.1 4.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2929) Autophagy_C PF10381.9 CRK11068.1 - 0.33 10.5 3.0 16 5.1 0.2 2.7 2 0 0 2 2 2 0 Autophagocytosis associated protein C-terminal MARVEL PF01284.23 CRK11069.1 - 0.046 13.7 5.6 2.1 8.4 1.0 2.4 1 1 1 2 2 2 0 Membrane-associating domain Urb2 PF10441.9 CRK11069.1 - 0.21 11.5 0.1 0.37 10.7 0.1 1.3 1 0 0 1 1 1 0 Urb2/Npa2 family Galactosyl_T PF01762.21 CRK11070.1 - 8.4e-15 55.1 2.1 4.6e-14 52.7 2.1 1.9 1 1 0 1 1 1 1 Galactosyltransferase Ribonuc_L-PSP PF01042.21 CRK11071.1 - 1.3e-26 92.9 0.0 1.8e-26 92.5 0.0 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP Amino_oxidase PF01593.24 CRK11072.1 - 7.2e-39 134.3 0.4 9.5e-38 130.6 0.5 2.6 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CRK11072.1 - 5.1e-06 26.6 0.0 2.6e-05 24.4 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 CRK11072.1 - 0.00071 18.9 0.5 0.0014 17.9 0.5 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 CRK11072.1 - 0.0024 17.1 0.0 0.0059 15.9 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CRK11072.1 - 0.039 13.2 0.2 0.19 10.9 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N PF00107.26 CRK11074.1 - 1.6e-28 99.2 0.3 3.2e-28 98.3 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CRK11074.1 - 1.7e-25 90.6 0.0 4.1e-25 89.4 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CRK11074.1 - 3.1e-06 27.0 0.1 9.3e-06 25.5 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 CRK11074.1 - 0.0026 17.3 0.1 0.0036 16.8 0.1 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus Cutinase PF01083.22 CRK11075.1 - 1.3e-26 93.7 0.3 4e-25 88.8 0.3 2.0 1 1 0 1 1 1 1 Cutinase VirJ PF06057.11 CRK11075.1 - 0.0026 17.6 0.0 0.0034 17.3 0.0 1.1 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) PE-PPE PF08237.11 CRK11075.1 - 0.0073 15.9 0.2 0.013 15.0 0.2 1.4 1 1 0 1 1 1 1 PE-PPE domain Hydrolase_4 PF12146.8 CRK11075.1 - 0.078 12.2 0.0 0.078 12.2 0.0 1.1 1 0 0 1 1 1 0 Serine aminopeptidase, S33 LIP PF03583.14 CRK11075.1 - 0.14 11.4 0.1 2.4 7.4 0.0 2.0 2 0 0 2 2 2 0 Secretory lipase Aa_trans PF01490.18 CRK11077.1 - 1.7e-17 63.3 1.5 1.9e-17 63.1 1.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Acetyltransf_1 PF00583.25 CRK11078.1 - 2.2e-06 27.9 0.0 5.4e-05 23.4 0.0 2.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Glyco_hydro_3_C PF01915.22 CRK11078.1 - 0.00095 19.2 0.0 0.0016 18.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_7 PF13508.7 CRK11078.1 - 0.0051 17.2 0.0 0.061 13.8 0.0 2.7 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CRK11078.1 - 0.036 14.0 0.0 0.074 13.0 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 CRK11078.1 - 0.047 13.8 0.1 0.47 10.6 0.1 2.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain LSM PF01423.22 CRK11079.1 - 1.8e-20 72.4 0.1 2.2e-20 72.1 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CRK11079.1 - 0.00062 19.9 0.1 0.00093 19.3 0.1 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 CRK11079.1 - 0.00091 19.3 0.2 0.0012 18.8 0.2 1.2 1 0 0 1 1 1 1 Scd6-like Sm domain Rad60-SLD PF11976.8 CRK11080.1 - 2.6e-20 72.0 0.0 4.7e-20 71.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 CRK11080.1 - 2.7e-05 23.8 0.0 0.00082 19.1 0.0 2.4 2 0 0 2 2 2 1 Ubiquitin family NAD_binding_10 PF13460.6 CRK11080.1 - 0.00034 20.6 0.0 0.00088 19.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)H-binding TmoB PF06234.12 CRK11080.1 - 0.0016 18.5 0.0 0.01 15.9 0.1 2.3 2 0 0 2 2 2 1 Toluene-4-monooxygenase system protein B (TmoB) SURF2 PF05477.11 CRK11080.1 - 0.14 11.8 9.3 0.18 11.5 5.2 2.4 1 1 0 1 1 1 0 Surfeit locus protein 2 (SURF2) DXP_reductoisom PF02670.16 CRK11080.1 - 0.15 12.8 0.0 0.39 11.4 0.0 1.7 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase PGA2 PF07543.12 CRK11080.1 - 4.9 7.1 19.7 5.3 7.0 2.5 3.5 3 0 0 3 3 3 0 Protein trafficking PGA2 Ank_2 PF12796.7 CRK11081.1 - 1.5e-38 131.2 3.7 1.7e-13 51.0 0.0 9.4 7 1 2 9 9 9 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CRK11081.1 - 3.3e-32 110.5 4.3 3.5e-06 27.4 0.0 10.3 8 2 2 10 10 10 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 CRK11081.1 - 9.4e-29 99.1 3.8 0.00014 22.1 0.1 10.3 9 1 1 10 10 10 6 Ankyrin repeats (many copies) Ank PF00023.30 CRK11081.1 - 1.1e-24 85.7 11.2 0.0012 19.1 0.0 11.3 14 0 0 14 14 14 6 Ankyrin repeat Ank_3 PF13606.6 CRK11081.1 - 1.5e-24 83.4 2.7 0.0038 17.6 0.0 12.2 13 0 0 13 13 13 4 Ankyrin repeat Casc1 PF12366.8 CRK11081.1 - 0.27 10.7 3.7 0.63 9.5 3.7 1.6 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 PI-PLC-X PF00388.19 CRK11083.1 - 3.8e-10 39.5 0.0 5.7e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain His_biosynth PF00977.21 CRK11083.1 - 0.043 13.3 0.0 0.14 11.5 0.0 1.8 2 0 0 2 2 2 0 Histidine biosynthesis protein Regulator_TrmB PF11495.8 CRK11083.1 - 0.055 12.7 0.0 0.092 11.9 0.0 1.3 1 0 0 1 1 1 0 Archaeal transcriptional regulator TrmB ABC_tran PF00005.27 CRK11084.1 - 2.4e-27 96.1 0.0 3.8e-27 95.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 CRK11084.1 - 3.3e-13 49.5 4.4 5.7e-13 48.8 4.4 1.4 1 0 0 1 1 1 1 ABC-2 type transporter RsgA_GTPase PF03193.16 CRK11084.1 - 0.00036 20.5 0.3 0.00069 19.6 0.3 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 CRK11084.1 - 0.0069 16.8 0.0 0.029 14.8 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 CRK11084.1 - 0.008 15.8 0.1 0.016 14.8 0.1 1.4 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 CRK11084.1 - 0.0083 16.2 0.3 0.016 15.3 0.3 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 CRK11084.1 - 0.02 15.0 0.0 0.032 14.3 0.0 1.3 1 0 0 1 1 1 0 Dynamin family AAA_29 PF13555.6 CRK11084.1 - 0.046 13.5 0.5 0.098 12.4 0.5 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MeaB PF03308.16 CRK11084.1 - 0.076 12.0 0.1 0.15 11.0 0.1 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_21 PF13304.6 CRK11084.1 - 0.079 12.7 0.0 0.36 10.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system IIGP PF05049.13 CRK11084.1 - 0.08 12.0 0.2 0.12 11.4 0.2 1.1 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) DUF87 PF01935.17 CRK11084.1 - 0.47 10.5 2.3 0.81 9.7 2.3 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain ABC2_membrane_3 PF12698.7 CRK11084.1 - 0.54 9.3 6.8 0.92 8.6 6.8 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein ATP_bind_1 PF03029.17 CRK11084.1 - 1.4 8.7 3.7 0.7 9.6 1.4 1.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Glyco_hydr_30_2 PF14587.6 CRK11085.1 - 8.6e-17 61.8 8.7 7.5e-10 38.9 0.0 2.3 1 1 1 2 2 2 2 O-Glycosyl hydrolase family 30 Glyco_hydro_59 PF02057.15 CRK11085.1 - 1.8e-12 47.1 5.3 3.6e-12 46.1 5.3 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydro_30 PF02055.16 CRK11085.1 - 2.6e-10 39.8 0.2 4.5e-10 39.0 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30C PF17189.4 CRK11085.1 - 2.3e-09 37.3 0.0 7.1e-09 35.8 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_7 PF00840.20 CRK11086.1 - 1.3e-176 587.7 12.7 1.6e-176 587.3 12.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CBM_1 PF00734.18 CRK11086.1 - 5.8e-13 48.5 15.5 5.8e-13 48.5 15.5 4.1 3 1 0 3 3 3 1 Fungal cellulose binding domain SPATIAL PF15256.6 CRK11087.1 - 0.028 14.8 1.9 0.068 13.5 1.9 1.7 1 0 0 1 1 1 0 SPATIAL LapA_dom PF06305.11 CRK11087.1 - 0.2 11.5 0.1 0.48 10.3 0.1 1.6 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain SKG6 PF08693.10 CRK11087.1 - 0.23 10.9 2.6 0.45 10.0 2.6 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain LAL_C2 PF18603.1 CRK11088.1 - 0.31 11.2 1.8 2.5 8.3 0.1 2.2 1 1 1 2 2 2 0 L-amino acid ligase C-terminal domain 2 Sugar_tr PF00083.24 CRK11089.1 - 1.6e-114 383.3 20.6 1.9e-114 383.0 20.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK11089.1 - 4.3e-24 85.1 39.4 3.2e-19 69.1 9.1 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF3980 PF13140.6 CRK11089.1 - 8.9 6.8 7.5 5.3 7.6 0.8 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF3980) Tannase PF07519.11 CRK11090.1 - 2.4e-117 392.7 0.0 2.9e-117 392.5 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 CRK11090.1 - 0.022 14.0 0.0 0.071 12.4 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CRK11090.1 - 0.082 12.5 0.0 0.46 10.1 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold GST_C_3 PF14497.6 CRK11091.1 - 4.5e-32 110.2 0.1 9.3e-32 109.2 0.1 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CRK11091.1 - 1.1e-05 25.6 0.0 1.9e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CRK11091.1 - 0.0021 18.1 0.0 0.0036 17.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF1508 PF07411.12 CRK11091.1 - 0.025 14.5 0.1 0.056 13.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1508) Glyco_hydro_20 PF00728.22 CRK11092.1 - 3e-26 92.7 0.6 1.2e-25 90.7 0.6 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.15 CRK11092.1 - 2.7e-11 44.3 0.0 5.3e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Glyco_hydro_26 PF02156.15 CRK11093.1 - 3.5e-87 292.7 3.6 4.6e-87 292.4 3.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 CBM_35 PF16990.5 CRK11093.1 - 1.5e-26 93.0 0.6 2.7e-26 92.2 0.6 1.4 1 0 0 1 1 1 1 Carbohydrate binding module (family 35) Endotoxin_C PF03944.14 CRK11093.1 - 0.013 15.8 0.1 0.025 14.9 0.1 1.4 1 0 0 1 1 1 0 delta endotoxin CarboxypepD_reg PF13620.6 CRK11093.1 - 0.096 13.0 0.8 0.26 11.6 0.8 1.7 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain Glyco_hydro_43 PF04616.14 CRK11095.1 - 5.9e-33 114.4 0.1 7.5e-33 114.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_16 PF00722.21 CRK11096.1 - 4.8e-14 52.2 0.1 6.6e-14 51.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 CRK11096.1 - 5e-06 25.2 0.2 0.062 11.7 0.0 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) DUF2401 PF10287.9 CRK11096.1 - 0.086 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative TOS1-like glycosyl hydrolase (DUF2401) LDB19 PF13002.7 CRK11098.1 - 9.8e-30 103.7 1.7 1.1e-29 103.6 0.4 1.7 2 0 0 2 2 2 1 Arrestin_N terminal like Arrestin_N PF00339.29 CRK11098.1 - 1.5e-05 25.1 0.1 0.0001 22.4 0.0 2.3 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Abdominal-A PF12407.8 CRK11098.1 - 0.11 12.0 2.6 0.2 11.3 2.6 1.3 1 0 0 1 1 1 0 Homeobox protein H_lectin PF09458.10 CRK11099.1 - 2.4e-31 107.7 0.0 8.7e-11 41.9 0.0 3.5 3 0 0 3 3 3 3 H-type lectin domain Astacin PF01400.24 CRK11099.1 - 0.028 14.0 1.7 0.18 11.4 1.7 2.1 1 1 0 1 1 1 0 Astacin (Peptidase family M12A) DUF4377 PF14302.6 CRK11099.1 - 0.034 14.2 0.0 0.24 11.5 0.0 2.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4377) Peptidase_M10 PF00413.24 CRK11099.1 - 0.04 13.8 2.1 2.2 8.1 2.0 2.6 1 1 0 1 1 1 0 Matrixin Reprolysin_5 PF13688.6 CRK11099.1 - 0.073 13.2 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12 DUF2207 PF09972.9 CRK11100.1 - 0.19 10.4 2.9 0.54 8.9 0.4 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF2383 PF09537.10 CRK11100.1 - 0.3 11.4 4.1 1.9 8.9 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF2383) Phage_holin_3_6 PF07332.11 CRK11100.1 - 1.6 8.8 10.5 3.5 7.7 5.3 2.7 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Trp_oprn_chp PF09534.10 CRK11100.1 - 9.4 6.0 11.1 1 9.2 0.1 3.1 3 0 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Ldh_1_N PF00056.23 CRK11101.1 - 7.9e-40 136.2 0.3 1.3e-39 135.5 0.3 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 CRK11101.1 - 6.4e-21 75.0 0.0 1.2e-20 74.1 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain DAO PF01266.24 CRK11101.1 - 0.00019 21.1 2.7 0.00023 20.9 2.2 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase ThiF PF00899.21 CRK11101.1 - 0.00028 20.3 0.1 0.00041 19.8 0.1 1.3 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 CRK11101.1 - 0.00038 20.7 0.5 0.00081 19.7 0.2 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Glyco_hydro_4 PF02056.16 CRK11101.1 - 0.0011 18.6 1.8 0.14 11.7 0.0 2.8 2 1 1 3 3 3 2 Family 4 glycosyl hydrolase UDPG_MGDP_dh_N PF03721.14 CRK11101.1 - 0.0013 18.3 0.7 0.0024 17.5 0.7 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.6 CRK11101.1 - 0.0051 17.2 0.2 0.0088 16.5 0.2 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding 3HCDH_N PF02737.18 CRK11101.1 - 0.0062 16.4 0.1 0.0094 15.9 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 CRK11101.1 - 0.034 14.4 0.8 0.12 12.7 0.4 2.1 2 1 1 3 3 3 0 TrkA-N domain NAD_binding_8 PF13450.6 CRK11101.1 - 0.26 11.5 2.5 0.43 10.8 0.6 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain PA_decarbox PF05870.11 CRK11103.1 - 4.6e-09 36.1 0.2 5.4e-09 35.9 0.2 1.1 1 0 0 1 1 1 1 Phenolic acid decarboxylase (PAD) AA_permease PF00324.21 CRK11104.1 - 2.3e-05 23.2 1.9 2.9e-05 22.9 1.9 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2101 PF09874.9 CRK11104.1 - 0.082 12.6 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2101) BTK PF00779.19 CRK11105.1 - 0.064 13.1 1.7 0.064 13.1 1.7 2.1 2 0 0 2 2 2 0 BTK motif AF-4 PF05110.13 CRK11105.1 - 0.084 11.0 1.8 0.086 10.9 1.8 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein AA_permease PF00324.21 CRK11107.1 - 7.9e-116 387.5 41.9 9.7e-116 387.2 41.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CRK11107.1 - 2.8e-35 122.0 47.6 3.7e-35 121.6 47.6 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2101 PF09874.9 CRK11107.1 - 0.027 14.2 0.1 0.027 14.2 0.1 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2101) AF-4 PF05110.13 CRK11108.1 - 0.1 10.7 2.1 0.12 10.5 2.1 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Peptidase_M28 PF04389.17 CRK11109.1 - 1.1e-33 116.6 0.1 1.2e-32 113.2 0.1 2.0 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.28 CRK11109.1 - 7.1e-06 25.9 0.6 8.8e-05 22.3 0.6 2.2 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Oxidored_FMN PF00724.20 CRK11110.1 - 1.7e-62 211.7 0.0 3.4e-62 210.7 0.0 1.5 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family MFS_1 PF07690.16 CRK11111.1 - 2e-32 112.5 27.8 1.9e-31 109.3 27.8 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 CRK11111.1 - 5.1e-16 58.2 14.8 5.5e-16 58.1 14.8 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 CRK11111.1 - 7.5e-15 54.7 12.2 1.2e-14 54.1 12.2 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 CRK11111.1 - 0.0015 17.5 7.1 0.0025 16.8 7.1 1.3 1 0 0 1 1 1 1 MFS_1 like family HlyIII PF03006.20 CRK11111.1 - 0.05 13.3 3.9 0.072 12.8 3.2 1.8 1 1 1 2 2 2 0 Haemolysin-III related Gtr1_RagA PF04670.12 CRK11119.1 - 2.2e-15 56.7 0.1 2.8e-15 56.3 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsfS PF02410.15 CRK11121.1 - 5.4e-05 23.5 0.0 0.00011 22.6 0.0 1.5 1 1 0 1 1 1 1 Ribosomal silencing factor during starvation STT3 PF02516.14 CRK11125.1 - 2.7e-55 188.2 17.2 2.9e-55 188.1 17.2 1.0 1 0 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit PMT PF02366.18 CRK11125.1 - 0.00061 19.5 14.0 0.00077 19.1 14.0 1.0 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Sugar_tr PF00083.24 CRK11157.1 - 3.9e-08 32.6 0.5 5.1e-08 32.2 0.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter tRNA-synt_2 PF00152.20 CRK11177.1 - 8.1e-61 205.8 0.1 1.2e-60 205.2 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.9 CRK11177.1 - 1.4e-15 57.1 0.1 2.4e-15 56.3 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) tRNA_anti-codon PF01336.25 CRK11177.1 - 5.9e-08 32.6 0.0 1.2e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain MCM_N PF14551.6 CRK11177.1 - 0.096 13.3 0.0 0.28 11.8 0.0 1.8 1 0 0 1 1 1 0 MCM N-terminal domain Glyco_hydro_75 PF07335.11 CRK11178.1 - 1.2e-64 217.5 1.4 1.7e-64 217.0 1.4 1.2 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 Ctr PF04145.15 CRK11180.1 - 9e-35 120.5 0.0 1.1e-34 120.2 0.0 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Ferric_reduct PF01794.19 CRK11181.1 - 1.6e-23 83.1 8.2 1.6e-23 83.1 8.2 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 CRK11181.1 - 5.4e-16 59.1 0.0 8.5e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 CRK11181.1 - 8.5e-11 41.9 0.0 2.2e-10 40.6 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 CRK11181.1 - 7.7e-06 26.5 0.0 1.7e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DUF3857 PF12969.7 CRK11181.1 - 0.17 12.0 0.0 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3857) Sdh_cyt PF01127.22 CRK11181.1 - 4.1 7.5 10.3 1.1 9.2 4.2 2.8 3 0 0 3 3 3 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit MFS_1 PF07690.16 CRK11183.1 - 4e-20 72.1 19.9 4e-20 72.1 19.9 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily UcrQ PF02939.16 CRK11183.1 - 0.057 13.4 0.2 0.19 11.7 0.2 2.0 1 0 0 1 1 1 0 UcrQ family GRDP-like PF07173.12 CRK11185.1 - 9.7e-23 81.4 1.1 2.5e-15 57.4 0.3 2.6 2 0 0 2 2 2 2 Glycine-rich domain-containing protein-like Sugar_tr PF00083.24 CRK11186.1 - 1.5e-135 452.6 29.5 1.8e-135 452.4 29.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK11186.1 - 1.2e-25 90.3 32.9 1.4e-16 60.3 12.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Trep_Strep PF09605.10 CRK11186.1 - 2.3 8.2 0.0 2.3 8.2 0.0 4.0 3 1 1 4 4 4 0 Hypothetical bacterial integral membrane protein (Trep_Strep) SirB PF04247.12 CRK11186.1 - 6.3 6.9 11.2 0.64 10.1 0.5 3.0 4 0 0 4 4 4 0 Invasion gene expression up-regulator, SirB Pox_A14 PF05767.12 CRK11186.1 - 9.9 6.4 13.3 2.3 8.4 0.0 4.2 3 1 1 4 4 4 0 Poxvirus virion envelope protein A14 RCDG1 PF15725.5 CRK11187.1 - 0.023 15.1 0.9 0.023 15.1 0.9 2.5 2 1 0 2 2 2 0 Renal cancer differentiation gene 1 protein F-box-like PF12937.7 CRK11188.1 - 0.0016 18.3 2.4 0.0019 18.0 0.4 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CRK11188.1 - 0.088 12.7 3.3 0.13 12.2 0.5 2.5 3 0 0 3 3 3 0 F-box domain Apolipoprotein PF01442.18 CRK11189.1 - 7.5e-08 32.5 15.2 0.0012 18.8 3.0 3.4 2 1 0 3 3 3 2 Apolipoprotein A1/A4/E domain Arg_decarb_HB PF17810.1 CRK11189.1 - 0.0028 17.9 1.1 0.053 13.8 0.3 3.1 3 0 0 3 3 3 1 Arginine decarboxylase helical bundle domain ISG65-75 PF11727.8 CRK11189.1 - 0.0044 16.3 3.3 0.0044 16.3 3.3 3.9 2 1 0 4 4 4 1 Invariant surface glycoprotein DUF883 PF05957.13 CRK11189.1 - 0.036 14.7 14.2 4.7 7.9 0.0 5.5 3 1 2 5 5 5 0 Bacterial protein of unknown function (DUF883) Cdc6_C PF09079.11 CRK11189.1 - 0.08 12.9 0.0 0.86 9.6 0.0 2.3 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain OHCU_decarbox PF09349.10 CRK11189.1 - 0.16 12.4 5.1 0.78 10.2 0.0 3.3 1 1 3 4 4 4 0 OHCU decarboxylase SMBP PF16785.5 CRK11189.1 - 2.5 8.4 15.1 0.87 9.8 8.0 3.5 3 1 0 3 3 3 0 Small metal-binding protein MCU PF04678.13 CRK11189.1 - 5.1 7.2 8.0 0.97 9.5 0.7 2.8 3 1 0 3 3 3 0 Mitochondrial calcium uniporter GST_N_3 PF13417.6 CRK11190.1 - 3e-10 40.4 0.1 6.5e-10 39.3 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CRK11190.1 - 5.7e-09 36.2 0.1 1.3e-08 35.0 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 CRK11190.1 - 2.3e-07 31.1 0.0 3.9e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CRK11190.1 - 8.4e-05 22.7 0.0 0.00016 21.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CRK11190.1 - 0.00081 19.4 0.1 0.0018 18.2 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CRK11190.1 - 0.0044 17.2 0.0 0.0078 16.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MARVEL PF01284.23 CRK11192.1 - 0.0029 17.6 8.8 0.0092 16.0 8.8 1.9 1 1 0 1 1 1 1 Membrane-associating domain Urb2 PF10441.9 CRK11192.1 - 0.091 12.7 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 Urb2/Npa2 family ATP19 PF11022.8 CRK11192.1 - 0.46 10.9 2.3 1.6 9.2 0.4 2.7 2 0 0 2 2 2 0 ATP synthase subunit K Galactosyl_T PF01762.21 CRK11193.1 - 9.4e-16 58.2 2.5 2.8e-15 56.6 2.5 1.7 1 1 0 1 1 1 1 Galactosyltransferase Ribonuc_L-PSP PF01042.21 CRK11194.1 - 6.9e-27 93.9 0.0 9.4e-27 93.4 0.0 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP BTK PF00779.19 CRK11195.1 - 0.14 12.0 2.9 0.39 10.6 2.9 1.8 1 0 0 1 1 1 0 BTK motif DUF5560 PF17715.1 CRK11196.1 - 8.9 5.7 21.7 1.4 8.3 9.8 2.4 1 1 1 2 2 2 0 Family of unknown function (DUF5560) T2SSI PF02501.17 CRK11197.1 - 0.049 13.8 0.0 14 6.0 0.0 3.0 2 1 1 3 3 3 0 Type II secretion system (T2SS), protein I Glyco_hydro_45 PF02015.16 CRK11197.1 - 0.27 11.1 6.4 0.47 10.3 0.1 2.2 2 0 0 2 2 2 0 Glycosyl hydrolase family 45 Zip PF02535.22 CRK11198.1 - 3.1e-32 112.1 33.6 3.3e-15 56.2 3.0 3.5 1 1 1 3 3 3 3 ZIP Zinc transporter Far-17a_AIG1 PF04750.14 CRK11198.1 - 0.13 11.5 0.1 0.13 11.5 0.1 2.1 2 0 0 2 2 2 0 FAR-17a/AIG1-like protein Amidase PF01425.21 CRK11200.1 - 4.3e-70 236.9 0.1 2.7e-69 234.3 0.1 1.9 1 1 0 1 1 1 1 Amidase Zip PF02535.22 CRK11202.1 - 2.6e-33 115.7 35.4 2.2e-16 60.0 2.5 3.5 1 1 1 3 3 3 3 ZIP Zinc transporter Far-17a_AIG1 PF04750.14 CRK11202.1 - 0.06 12.7 3.7 0.085 12.2 0.1 2.3 2 0 0 2 2 2 0 FAR-17a/AIG1-like protein Amidase PF01425.21 CRK11203.1 - 5.1e-70 236.7 0.1 2.6e-69 234.4 0.1 1.9 1 1 0 1 1 1 1 Amidase HemY_N PF07219.13 CRK11204.1 - 5.5 7.2 7.9 3.3 7.9 0.7 2.5 2 0 0 2 2 2 0 HemY protein N-terminus Beta_helix PF13229.6 CRK11206.1 - 1.6e-12 47.6 17.8 2.1e-08 34.2 5.3 3.4 1 1 2 3 3 3 3 Right handed beta helix region NosD PF05048.13 CRK11206.1 - 5.2e-05 22.6 7.8 0.019 14.2 0.7 2.4 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) Cu_amine_oxidN1 PF07833.11 CRK11207.1 - 1.2 9.7 7.9 1.2 9.6 2.7 2.3 1 1 1 2 2 2 0 Copper amine oxidase N-terminal domain tRNA-synt_1 PF00133.22 CRK11208.1 - 1.9e-35 122.2 0.0 7.2e-27 93.9 0.0 3.2 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 CRK11208.1 - 2.3e-13 49.7 0.1 2.1e-08 33.4 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 CRK11208.1 - 1e-09 38.5 0.7 2.1e-09 37.5 0.7 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 CRK11208.1 - 5.3e-07 29.3 0.2 1.1e-06 28.2 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain Lactamase_B PF00753.27 CRK11208.1 - 0.0015 18.6 1.4 0.0031 17.5 1.4 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily NAD_binding_6 PF08030.12 CRK11210.1 - 1.6e-24 86.8 0.0 2.4e-24 86.3 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 CRK11210.1 - 7.8e-22 77.4 0.0 1.6e-21 76.4 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 CRK11210.1 - 5e-09 36.3 5.7 1e-08 35.3 5.7 1.5 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.24 CRK11210.1 - 0.061 13.7 0.0 0.14 12.5 0.0 1.6 1 1 0 1 1 1 0 Oxidoreductase FAD-binding domain Clat_adaptor_s PF01217.20 CRK11212.1 - 2.3e-43 147.6 0.0 3.9e-43 146.8 0.0 1.4 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Frataxin_Cyay PF01491.16 CRK11213.1 - 3.1e-36 123.7 0.0 4e-36 123.4 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain MFS_1 PF07690.16 CRK11215.1 - 4.1e-23 81.9 63.8 2.8e-21 75.8 37.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Fes1 PF08609.10 CRK11222.1 - 2.1e-12 47.8 1.4 2.1e-12 47.8 1.4 2.0 2 1 1 3 3 3 1 Nucleotide exchange factor Fes1 Arm PF00514.23 CRK11222.1 - 9.1e-06 25.5 0.2 0.015 15.4 0.1 2.6 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 CRK11222.1 - 4.7e-05 23.8 0.6 0.00013 22.4 0.4 1.8 2 0 0 2 2 2 1 HEAT-like repeat HEAT PF02985.22 CRK11222.1 - 0.0001 22.3 0.4 0.0089 16.2 0.1 2.8 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.6 CRK11222.1 - 0.00019 21.8 0.5 0.00038 20.8 0.5 1.5 1 1 0 1 1 1 1 HEAT repeats FeoA PF04023.14 CRK11222.1 - 0.13 12.5 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 FeoA domain Rota_VP2 PF05087.12 CRK11222.1 - 0.14 10.2 0.0 0.17 10.0 0.0 1.0 1 0 0 1 1 1 0 Rotavirus VP2 protein MFS_1 PF07690.16 CRK11224.1 - 4.6e-29 101.5 11.9 5.1e-29 101.3 11.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK11224.1 - 8.6e-15 54.5 5.5 1e-14 54.3 5.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 CRK11224.1 - 1.8e-06 26.7 6.6 2.4e-06 26.3 6.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 CRK11224.1 - 0.019 13.4 6.3 0.02 13.3 6.3 1.1 1 0 0 1 1 1 0 Transmembrane secretion effector MFS_1_like PF12832.7 CRK11224.1 - 0.064 12.1 7.4 0.099 11.5 7.4 1.4 1 0 0 1 1 1 0 MFS_1 like family ATP-synt PF00231.19 CRK11226.1 - 3e-15 56.7 0.0 3e-15 56.7 0.0 1.0 1 0 0 1 1 1 1 ATP synthase Matrilin_ccoil PF10393.9 CRK11232.1 - 0.14 12.0 0.2 0.38 10.7 0.1 1.7 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin PRA1 PF03208.19 CRK11249.1 - 2.5e-08 33.7 3.4 2.6e-08 33.6 3.4 1.0 1 0 0 1 1 1 1 PRA1 family protein DUF3094 PF11293.8 CRK11249.1 - 0.52 10.1 2.1 3.7 7.4 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) OB_Dis3 PF17849.1 CRK11267.1 - 3.5e-21 75.0 0.0 9.1e-21 73.7 0.0 1.8 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 CRK11267.1 - 0.0016 18.6 0.0 0.73 10.0 0.0 2.6 2 0 0 2 2 2 2 Cold shock domain Rrp44_CSD1 PF17216.3 CRK11267.1 - 0.0025 17.5 0.0 0.0045 16.7 0.0 1.3 1 0 0 1 1 1 1 Rrp44-like cold shock domain Tis11B_N PF04553.12 CRK11267.1 - 0.66 10.5 3.3 16 6.0 0.3 3.1 2 1 1 3 3 3 0 Tis11B like protein, N terminus NPR3 PF03666.13 CRK11267.1 - 3.7 6.2 8.3 0.076 11.8 1.1 1.8 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 APH PF01636.23 CRK11285.1 - 5.4e-09 36.3 0.0 8.9e-09 35.6 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1996 PF09362.10 CRK11286.1 - 8.6e-61 205.9 0.2 1e-60 205.7 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Aegerolysin PF06355.13 CRK11286.1 - 0.19 11.8 0.0 0.46 10.6 0.0 1.6 1 0 0 1 1 1 0 Aegerolysin B12-binding PF02310.19 CRK11287.1 - 0.0058 16.7 0.4 0.024 14.7 0.1 2.0 2 0 0 2 2 2 1 B12 binding domain VBS PF08913.10 CRK11287.1 - 0.1 13.1 2.2 0.11 13.0 0.7 1.8 2 0 0 2 2 2 0 Vinculin Binding Site DUF4248 PF14053.6 CRK11287.1 - 0.34 11.0 2.8 1.5 8.9 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4248) ADIP PF11559.8 CRK11287.1 - 0.37 10.9 24.8 0.21 11.7 9.7 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding ATG16 PF08614.11 CRK11287.1 - 1.1 9.5 23.2 2.8 8.1 23.2 1.7 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Rootletin PF15035.6 CRK11287.1 - 4.4 7.3 24.7 14 5.7 21.5 2.6 2 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion APG6_N PF17675.1 CRK11287.1 - 4.8 7.7 27.3 6.3e+02 0.9 9.4 2.6 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF501 PF04417.12 CRK11287.1 - 4.8 7.0 7.3 0.52 10.1 1.1 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF501) DUF4407 PF14362.6 CRK11287.1 - 6.6 6.0 14.2 11 5.2 14.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) BST2 PF16716.5 CRK11287.1 - 6.8 7.4 14.0 0.48 11.1 5.2 3.3 1 1 1 3 3 3 0 Bone marrow stromal antigen 2 XhlA PF10779.9 CRK11287.1 - 9.3 6.5 8.6 9.4 6.5 1.8 2.8 1 1 1 2 2 2 0 Haemolysin XhlA APH PF01636.23 CRK11290.1 - 1e-12 48.5 0.0 2.1e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CRK11290.1 - 0.011 15.4 0.0 0.044 13.4 0.0 2.0 2 0 0 2 2 2 0 Choline/ethanolamine kinase Fungal_trans PF04082.18 CRK11291.1 - 4.4e-24 84.9 0.2 8.6e-24 84.0 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK11291.1 - 3.9e-05 23.7 1.5 0.00011 22.3 1.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IFN-gamma PF00714.17 CRK11291.1 - 0.12 12.2 0.0 0.32 10.8 0.0 1.7 1 0 0 1 1 1 0 Interferon gamma COesterase PF00135.28 CRK11292.1 - 1.8e-52 178.9 0.1 3.9e-46 158.0 0.1 2.6 2 1 1 3 3 3 2 Carboxylesterase family Abhydrolase_3 PF07859.13 CRK11292.1 - 5.6e-06 26.4 0.0 3.9e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CRK11292.1 - 0.071 12.6 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family peroxidase PF00141.23 CRK11294.1 - 1.5e-34 119.7 0.0 2.2e-34 119.2 0.0 1.2 1 0 0 1 1 1 1 Peroxidase Abhydrolase_6 PF12697.7 CRK11296.1 - 0.00012 22.8 2.6 0.00022 21.9 0.5 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CRK11296.1 - 0.00089 19.0 0.1 0.0015 18.2 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 CRK11296.1 - 0.0046 16.8 0.3 0.0076 16.1 0.3 1.3 1 0 0 1 1 1 1 Serine hydrolase PGAP1 PF07819.13 CRK11296.1 - 0.048 13.4 0.6 0.16 11.6 0.6 1.7 1 1 0 1 1 1 0 PGAP1-like protein Hydrolase_4 PF12146.8 CRK11296.1 - 0.12 11.6 0.0 0.41 9.9 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Pkinase_Tyr PF07714.17 CRK11297.1 - 1.4e-11 44.2 0.2 2e-11 43.7 0.2 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CRK11297.1 - 1.6e-11 44.1 0.3 2.2e-11 43.6 0.3 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 CRK11297.1 - 0.048 13.0 0.0 0.19 11.0 0.0 1.7 1 1 1 2 2 2 0 Kinase-like DUF3723 PF12520.8 CRK11298.1 - 9.3e-43 146.7 0.0 1.1e-42 146.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3723) DUF4763 PF15960.5 CRK11299.1 - 0.021 14.2 2.8 0.038 13.3 2.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) OAS1_C PF10421.9 CRK11299.1 - 0.11 12.0 0.1 0.2 11.1 0.1 1.3 1 0 0 1 1 1 0 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus Tropomyosin_1 PF12718.7 CRK11300.1 - 0.034 14.3 0.2 0.053 13.7 0.2 1.2 1 0 0 1 1 1 0 Tropomyosin like HAP1_N PF04849.13 CRK11300.1 - 0.068 12.4 1.2 0.83 8.8 0.2 2.0 1 1 1 2 2 2 0 HAP1 N-terminal conserved region DUF4763 PF15960.5 CRK11300.1 - 0.076 12.3 0.1 0.1 11.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) CENP-F_leu_zip PF10473.9 CRK11300.1 - 0.1 12.7 0.5 0.13 12.3 0.5 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PspB PF06667.12 CRK11300.1 - 0.11 12.6 0.7 0.36 10.9 0.0 2.1 2 1 1 3 3 3 0 Phage shock protein B EB1 PF03271.17 CRK11301.1 - 0.13 12.6 0.6 0.29 11.4 0.6 1.6 1 0 0 1 1 1 0 EB1-like C-terminal motif Pkinase_fungal PF17667.1 CRK11302.1 - 1.2e-46 159.4 0.9 1.8e-45 155.4 1.1 2.0 1 1 0 1 1 1 1 Fungal protein kinase DUF2239 PF09998.9 CRK11302.1 - 0.13 12.0 0.1 0.48 10.2 0.1 1.9 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2239) Methyltransf_23 PF13489.6 CRK11307.1 - 3.7e-08 33.4 0.0 5e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CRK11307.1 - 4.2e-05 24.1 0.0 0.00056 20.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK11307.1 - 0.0012 18.7 0.0 0.0081 16.0 0.0 1.7 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK11307.1 - 0.0033 18.1 0.0 0.013 16.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain CheR PF01739.18 CRK11307.1 - 0.0062 16.0 0.0 0.023 14.2 0.0 1.8 2 0 0 2 2 2 1 CheR methyltransferase, SAM binding domain Methyltransf_25 PF13649.6 CRK11307.1 - 0.02 15.6 0.0 0.67 10.7 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain AAA PF00004.29 CRK11308.1 - 3.6e-19 69.5 0.0 7.2e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CRK11308.1 - 0.00058 19.9 0.2 0.12 12.3 0.0 2.7 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CRK11308.1 - 0.0022 18.4 1.5 0.013 15.9 0.8 2.7 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 CRK11308.1 - 0.0025 17.6 0.0 0.0044 16.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 CRK11308.1 - 0.0026 18.1 0.0 0.0046 17.3 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_24 PF13479.6 CRK11308.1 - 0.008 15.9 0.0 0.063 13.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 CRK11308.1 - 0.028 13.6 0.0 0.051 12.8 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_25 PF13481.6 CRK11308.1 - 0.045 13.3 0.1 0.22 11.1 0.0 2.2 2 1 2 4 4 4 0 AAA domain DUF815 PF05673.13 CRK11308.1 - 0.065 12.4 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_18 PF13238.6 CRK11308.1 - 0.073 13.6 0.0 0.13 12.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain UPF0047 PF01894.17 CRK11308.1 - 0.15 12.3 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0047 ATP-synt_Z PF16594.5 CRK11309.1 - 0.09 12.3 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 Putative AtpZ or ATP-synthase-associated MucB_RseB_C PF17188.4 CRK11310.1 - 0.14 12.4 0.0 0.28 11.5 0.0 1.5 1 0 0 1 1 1 0 MucB/RseB C-terminal domain Kelch_5 PF13854.6 CRK11314.1 - 1.2e-09 37.9 2.7 3.1e-08 33.4 0.1 4.0 4 0 0 4 4 4 1 Kelch motif Kelch_1 PF01344.25 CRK11314.1 - 0.0088 15.6 1.0 9.7 5.9 0.0 4.0 4 1 0 4 4 4 2 Kelch motif SKG6 PF08693.10 CRK11314.1 - 5.5 6.5 7.1 0.65 9.5 1.4 2.5 2 0 0 2 2 2 0 Transmembrane alpha-helix domain APH PF01636.23 CRK11316.1 - 3e-12 47.0 0.0 6.3e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CRK11316.1 - 0.016 14.8 0.0 0.036 13.6 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Reeler PF02014.16 CRK11318.1 - 0.13 13.0 0.0 0.2 12.4 0.0 1.2 1 0 0 1 1 1 0 Reeler domain FAM117 PF15388.6 CRK11319.1 - 6.6e-05 22.5 3.4 8.5e-05 22.1 3.4 1.1 1 0 0 1 1 1 1 Protein Family FAM117 B12-binding PF02310.19 CRK11320.1 - 0.016 15.2 0.1 0.04 14.0 0.1 1.6 1 0 0 1 1 1 0 B12 binding domain Myb_DNA-bind_3 PF12776.7 CRK11320.1 - 0.054 14.5 0.5 0.19 12.7 0.5 2.0 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain ADIP PF11559.8 CRK11320.1 - 0.057 13.5 23.6 0.025 14.7 8.0 2.7 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding CALCOCO1 PF07888.11 CRK11320.1 - 0.16 10.8 18.6 0.23 10.3 18.6 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Leu_zip PF15294.6 CRK11320.1 - 0.2 11.1 19.2 0.08 12.4 12.0 2.2 1 1 1 2 2 2 0 Leucine zipper DUF501 PF04417.12 CRK11320.1 - 0.57 10.0 4.3 0.3 10.9 1.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF501) CENP-Q PF13094.6 CRK11320.1 - 0.78 9.9 22.1 0.53 10.5 10.6 2.5 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF4407 PF14362.6 CRK11320.1 - 4 6.7 14.2 6.5 6.0 14.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Imm71 PF15602.6 CRK11321.1 - 0.0044 17.1 0.1 0.005 16.9 0.1 1.2 1 0 0 1 1 1 1 Immunity protein 71 TMF_TATA_bd PF12325.8 CRK11321.1 - 0.0091 16.2 1.4 0.012 15.8 1.4 1.2 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding DUF5082 PF16888.5 CRK11321.1 - 0.049 13.9 0.9 0.049 13.9 0.9 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) DUF2383 PF09537.10 CRK11321.1 - 0.053 13.9 0.7 0.076 13.4 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) DUF1996 PF09362.10 CRK11322.1 - 1.6e-54 185.4 0.1 2.3e-54 184.9 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Patatin PF01734.22 CRK11322.1 - 2.6e-08 34.3 0.1 0.0043 17.2 0.0 2.9 2 0 0 2 2 2 2 Patatin-like phospholipase ETF_alpha PF00766.19 CRK11322.1 - 0.085 12.9 0.1 8 6.6 0.1 2.5 2 0 0 2 2 2 0 Electron transfer flavoprotein FAD-binding domain DIL PF01843.19 CRK11322.1 - 0.2 12.0 0.0 10 6.5 0.0 2.3 2 0 0 2 2 2 0 DIL domain RRM_8 PF11835.8 CRK11322.1 - 0.39 11.0 0.9 12 6.2 0.1 2.6 2 0 0 2 2 2 0 RRM-like domain Glyco_hydro_18 PF00704.28 CRK11323.1 - 1.2e-77 261.7 0.1 1.5e-77 261.4 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 APH PF01636.23 CRK11323.1 - 1.9e-08 34.5 0.0 4.5e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family zf-RING_11 PF17123.5 CRK11325.1 - 4.4 7.1 5.7 18 5.2 0.2 3.1 3 0 0 3 3 3 0 RING-like zinc finger zf-RING_11 PF17123.5 CRK11326.1 - 3.3 7.5 4.9 14 5.5 0.2 2.9 3 0 0 3 3 3 0 RING-like zinc finger Glyco_hydro_cc PF11790.8 CRK11327.1 - 5.7e-38 130.8 0.0 2.6e-37 128.7 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase catalytic core DUF1438 PF07270.11 CRK11328.1 - 0.23 11.5 3.3 2.9 7.9 0.5 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1438) DUF3037 PF11236.8 CRK11328.1 - 0.69 10.4 5.0 0.41 11.1 2.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3037) GAS PF13851.6 CRK11328.1 - 1.3 8.3 26.2 11 5.4 20.4 2.8 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding ATG16 PF08614.11 CRK11328.1 - 2 8.6 30.1 16 5.6 30.1 2.1 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Swi5 PF07061.11 CRK11328.1 - 2.4 8.3 16.4 19 5.4 0.2 3.7 3 1 0 3 3 3 0 Swi5 DUF1192 PF06698.11 CRK11328.1 - 3.1 7.9 8.8 15 5.7 6.8 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) LMBR1 PF04791.16 CRK11328.1 - 3.9 6.3 4.6 14 4.4 5.0 1.6 2 0 0 2 2 2 0 LMBR1-like membrane protein OmpH PF03938.14 CRK11328.1 - 7.4 6.9 31.6 0.037 14.3 13.1 3.1 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) DUF4407 PF14362.6 CRK11328.1 - 7.9 5.7 20.8 1.5 8.1 15.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Syntaxin-6_N PF09177.11 CRK11328.1 - 8.2 7.0 13.9 16 6.1 8.5 2.8 1 1 2 3 3 3 0 Syntaxin 6, N-terminal FAD_binding_8 PF08022.12 CRK11329.1 - 1.1e-13 51.1 0.1 2.1e-13 50.3 0.1 1.4 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 CRK11329.1 - 3e-11 43.5 3.8 3e-11 43.5 3.8 2.4 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 CRK11329.1 - 3.4e-09 37.0 0.0 5.9e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain DEAD PF00270.29 CRK11338.1 - 1.6e-06 28.0 0.0 5.6e-05 23.0 0.0 2.2 2 1 0 2 2 2 2 DEAD/DEAH box helicase Aminotran_1_2 PF00155.21 CRK11371.1 - 0.0067 15.6 0.0 0.0071 15.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Zn_clus PF00172.18 CRK11388.1 - 1.7e-08 34.5 9.7 3.7e-08 33.4 9.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tubulin-binding PF00418.19 CRK11388.1 - 0.024 14.6 0.2 0.064 13.3 0.2 1.7 1 0 0 1 1 1 0 Tau and MAP protein, tubulin-binding repeat FAD_binding_7 PF03441.14 CRK11390.1 - 5.7e-46 156.5 0.1 9.3e-46 155.8 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 CRK11390.1 - 5.3e-21 75.3 0.0 1e-20 74.4 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase Methyltransf_23 PF13489.6 CRK11390.1 - 0.00062 19.6 0.0 0.0057 16.5 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK11390.1 - 0.034 14.9 0.1 0.14 12.9 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Pkinase PF00069.25 CRK11392.1 - 2.1e-05 24.0 0.0 3.8e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 CRK11392.1 - 0.00081 18.8 0.0 0.0017 17.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family HSDR_N_2 PF13588.6 CRK11392.1 - 0.015 15.3 0.0 1.4 9.0 0.0 2.5 2 0 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) NUDE_C PF04880.13 CRK11392.1 - 0.017 15.6 0.7 0.017 15.6 0.7 2.6 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region YacG PF03884.14 CRK11392.1 - 0.058 13.1 0.1 0.15 11.8 0.1 1.6 1 0 0 1 1 1 0 DNA gyrase inhibitor YacG Macoilin PF09726.9 CRK11392.1 - 1.7 7.1 6.1 3 6.3 6.1 1.3 1 0 0 1 1 1 0 Macoilin family Trimer_CC PF08954.11 CRK11392.1 - 3.9 7.1 11.9 14 5.3 11.9 2.1 1 0 0 1 1 1 0 Trimerisation motif BRE1 PF08647.11 CRK11394.1 - 0.008 16.2 1.2 0.02 15.0 1.2 1.6 1 0 0 1 1 1 1 BRE1 E3 ubiquitin ligase TMF_TATA_bd PF12325.8 CRK11394.1 - 0.031 14.5 2.3 0.074 13.3 2.3 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding THOC7 PF05615.13 CRK11394.1 - 0.056 13.7 2.3 0.14 12.4 2.3 1.7 1 0 0 1 1 1 0 Tho complex subunit 7 Spc7 PF08317.11 CRK11394.1 - 0.21 10.4 2.5 0.35 9.7 2.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein ADIP PF11559.8 CRK11394.1 - 0.43 10.7 4.1 0.95 9.5 4.1 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding TSNAXIP1_N PF15739.5 CRK11394.1 - 0.48 10.8 2.7 1.1 9.7 2.7 1.6 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus DUF4191 PF13829.6 CRK11394.1 - 0.51 9.6 3.3 3.3 7.0 1.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) bZIP_1 PF00170.21 CRK11394.1 - 1.8 8.7 7.0 0.11 12.6 1.2 1.9 2 0 0 2 2 2 0 bZIP transcription factor Pkinase PF00069.25 CRK11398.1 - 1.3e-20 73.9 0.0 8.8e-10 38.4 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CRK11398.1 - 6.9e-10 38.6 0.0 4.6e-05 22.8 0.0 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CRK11398.1 - 0.00011 21.7 0.2 0.27 10.5 0.0 3.0 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.14 CRK11398.1 - 0.00011 21.6 0.0 0.00023 20.6 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CRK11398.1 - 0.046 13.6 0.1 0.079 12.9 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 CRK11400.1 - 1.3e-25 90.3 0.0 1.6e-25 90.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK11400.1 - 9.5e-13 48.0 0.0 1.3e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CRK11400.1 - 5.2e-08 32.1 0.0 7.7e-08 31.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CRK11400.1 - 0.0059 16.6 0.0 0.018 15.0 0.0 1.7 1 1 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 CRK11400.1 - 0.045 12.7 0.1 0.066 12.2 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase CBM_21 PF03370.13 CRK11402.1 - 8.2e-34 116.2 0.0 1.3e-33 115.6 0.0 1.3 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 CRK11402.1 - 1.1e-10 41.9 0.2 2.1e-10 41.0 0.2 1.4 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) Fungal_trans_2 PF11951.8 CRK11408.1 - 3.7e-08 32.6 0.3 7.6e-08 31.6 0.3 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK11408.1 - 2.6e-06 27.4 9.6 2.6e-06 27.4 9.6 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ACC_central PF08326.12 CRK11410.1 - 5.9e-281 934.0 0.0 7.3e-281 933.7 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 CRK11410.1 - 3.5e-181 603.2 0.0 4.8e-181 602.7 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 CRK11410.1 - 8.1e-52 175.8 0.0 1.5e-51 174.9 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 CRK11410.1 - 1.9e-27 96.0 0.1 4.1e-27 94.9 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 CRK11410.1 - 5.9e-22 77.8 0.0 5e-20 71.6 0.0 2.9 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 CRK11410.1 - 1.2e-17 63.5 0.1 2.7e-17 62.4 0.1 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 CRK11410.1 - 0.00073 19.1 0.0 0.0017 17.9 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 CRK11410.1 - 0.0031 17.3 0.1 0.01 15.6 0.0 1.9 2 0 0 2 2 2 1 Biotin-lipoyl like GxGYxYP_N PF16216.5 CRK11410.1 - 0.013 15.7 0.0 0.037 14.2 0.0 1.7 1 0 0 1 1 1 0 GxGYxY sequence motif in domain of unknown function N-terminal ATP-grasp_3 PF02655.14 CRK11410.1 - 0.02 14.9 0.0 0.089 12.8 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp domain RnfC_N PF13375.6 CRK11410.1 - 0.088 12.8 0.0 0.27 11.2 0.0 1.8 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain ATPgrasp_Ter PF15632.6 CRK11410.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon NUDE_C PF04880.13 CRK11412.1 - 8.3e-36 124.1 17.9 8.3e-36 124.1 17.9 4.6 2 1 2 4 4 2 1 NUDE protein, C-terminal conserved region ZapB PF06005.12 CRK11412.1 - 0.00048 20.5 8.8 0.00048 20.5 8.8 4.7 2 1 3 5 5 5 1 Cell division protein ZapB Tropomyosin_1 PF12718.7 CRK11412.1 - 0.35 11.0 34.3 0.38 10.9 22.0 3.4 2 1 1 3 3 3 0 Tropomyosin like YjbH PF06082.11 CRK11412.1 - 0.63 8.8 5.4 1 8.1 5.4 1.4 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH ERM PF00769.19 CRK11412.1 - 0.74 9.6 35.8 0.18 11.6 24.9 2.4 2 1 1 3 3 3 0 Ezrin/radixin/moesin family AAA_13 PF13166.6 CRK11412.1 - 0.86 8.2 20.7 1.3 7.5 20.7 1.2 1 0 0 1 1 1 0 AAA domain Fez1 PF06818.15 CRK11412.1 - 0.93 9.9 28.1 1.3 9.5 13.2 3.0 2 1 1 3 3 3 0 Fez1 Atg14 PF10186.9 CRK11412.1 - 1.1 8.2 27.4 0.19 10.8 9.6 2.8 2 1 1 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 Seryl_tRNA_N PF02403.22 CRK11412.1 - 1.2 9.4 19.8 0.88 9.8 8.2 3.2 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Chibby PF14645.6 CRK11412.1 - 2.6 8.5 10.5 2.4 8.6 0.6 2.5 1 1 1 2 2 2 0 Chibby family Filament PF00038.21 CRK11412.1 - 2.7 7.5 31.1 2.8 7.5 9.3 2.6 2 1 1 3 3 3 0 Intermediate filament protein ADIP PF11559.8 CRK11412.1 - 3.1 7.9 31.3 0.16 12.0 11.4 3.6 2 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding Prefoldin_2 PF01920.20 CRK11412.1 - 4.6 7.2 26.6 0.32 11.0 6.9 5.0 3 1 3 6 6 6 0 Prefoldin subunit DHHC PF01529.20 CRK11418.1 - 5.1e-33 114.0 12.5 5.1e-33 114.0 12.5 2.1 2 1 0 2 2 2 1 DHHC palmitoyltransferase Ank_2 PF12796.7 CRK11418.1 - 2.2e-20 73.0 0.0 2.3e-10 40.9 0.0 3.0 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CRK11418.1 - 9.6e-20 70.7 1.5 5.1e-06 26.9 0.3 4.8 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 CRK11418.1 - 2.8e-17 62.5 0.1 1.4e-07 31.6 0.0 4.9 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 CRK11418.1 - 2.5e-15 56.2 0.1 0.05 14.1 0.0 5.7 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 CRK11418.1 - 5.1e-15 54.1 0.4 0.11 13.2 0.0 5.7 5 0 0 5 5 5 4 Ankyrin repeat DZR PF12773.7 CRK11418.1 - 0.6 10.2 6.0 1.5 8.9 6.0 1.6 1 0 0 1 1 1 0 Double zinc ribbon PocR PF10114.9 CRK11418.1 - 0.95 9.2 3.0 2 8.2 3.0 1.4 1 0 0 1 1 1 0 Sensory domain found in PocR SRPRB PF09439.10 CRK11420.1 - 1.6e-26 92.8 0.0 1.3e-24 86.7 0.0 2.8 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CRK11420.1 - 0.00017 21.6 0.0 0.00028 20.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 CRK11420.1 - 0.0065 16.9 0.2 0.014 15.8 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 CRK11420.1 - 0.013 16.1 0.0 0.021 15.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.12 CRK11420.1 - 0.015 14.7 0.0 0.033 13.5 0.0 1.5 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Arf PF00025.21 CRK11420.1 - 0.018 14.5 0.0 0.79 9.2 0.0 2.5 3 0 0 3 3 3 0 ADP-ribosylation factor family cobW PF02492.19 CRK11420.1 - 0.022 14.3 0.1 0.69 9.5 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 CRK11420.1 - 0.024 14.6 0.0 0.04 13.9 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 CRK11420.1 - 0.05 14.1 0.0 0.068 13.7 0.0 1.3 1 0 0 1 1 1 0 ABC transporter SRP54 PF00448.22 CRK11420.1 - 0.06 13.0 0.2 9.2 5.8 0.2 2.2 1 1 1 2 2 2 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 CRK11420.1 - 0.061 12.6 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Sigma70_ECF PF07638.11 CRK11420.1 - 0.11 12.3 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 ECF sigma factor AAA PF00004.29 CRK11420.1 - 0.14 12.6 0.4 0.26 11.7 0.4 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CRK11420.1 - 0.14 12.4 0.0 0.26 11.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain SSF PF00474.17 CRK11423.1 - 5.2e-20 71.7 27.5 8.3e-20 71.0 27.5 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family adh_short_C2 PF13561.6 CRK11425.1 - 2e-55 187.9 0.4 2.9e-55 187.4 0.4 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRK11425.1 - 1.4e-46 158.5 2.0 1.7e-46 158.2 2.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CRK11425.1 - 1.3e-11 44.7 0.2 1.7e-11 44.4 0.2 1.1 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 CRK11425.1 - 0.00066 19.7 0.3 0.09 12.8 0.3 2.3 1 1 0 1 1 1 1 Zinc-binding dehydrogenase THF_DHG_CYH_C PF02882.19 CRK11425.1 - 0.012 15.0 0.2 0.023 14.0 0.2 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 2-Hacid_dh_C PF02826.19 CRK11425.1 - 0.16 11.3 0.1 0.27 10.6 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Mistic PF11458.8 CRK11425.1 - 0.16 11.9 0.2 0.3 11.1 0.2 1.3 1 0 0 1 1 1 0 Membrane-integrating protein Mistic FAD_binding_3 PF01494.19 CRK11428.1 - 3e-27 95.8 0.0 2.1e-26 93.0 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 CRK11428.1 - 9.5e-07 28.4 0.0 1.6e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CRK11428.1 - 1e-05 25.6 0.1 2.8e-05 24.3 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CRK11428.1 - 0.00018 20.9 0.1 0.00043 19.6 0.1 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 CRK11428.1 - 0.00021 20.8 0.0 0.22 10.7 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 CRK11428.1 - 0.00056 19.4 0.0 0.001 18.5 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 CRK11428.1 - 0.0011 17.9 0.0 0.0016 17.4 0.0 1.2 1 0 0 1 1 1 1 Tryptophan halogenase FAD_binding_2 PF00890.24 CRK11428.1 - 0.0016 17.6 0.0 0.0034 16.5 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 CRK11428.1 - 0.0016 18.1 0.6 0.0061 16.2 0.3 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 CRK11428.1 - 0.0027 18.2 0.1 0.006 17.1 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CRK11428.1 - 0.0072 15.1 0.0 0.017 13.9 0.1 1.5 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 CRK11428.1 - 0.015 14.6 0.0 0.032 13.5 0.0 1.5 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 CRK11428.1 - 0.022 13.9 0.1 0.032 13.3 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Glycophorin_A PF01102.18 CRK11429.1 - 0.021 15.0 0.2 1.2 9.5 0.0 2.7 2 0 0 2 2 2 0 Glycophorin A Rax2 PF12768.7 CRK11429.1 - 0.077 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DUF347 PF03988.12 CRK11429.1 - 0.098 12.9 0.6 0.19 12.0 0.6 1.4 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) VSP PF03302.13 CRK11429.1 - 0.22 10.3 1.1 0.36 9.6 1.1 1.3 1 0 0 1 1 1 0 Giardia variant-specific surface protein Podoplanin PF05808.11 CRK11429.1 - 0.5 10.4 0.1 0.5 10.4 0.1 2.6 2 1 0 3 3 3 0 Podoplanin SARAF PF06682.12 CRK11429.1 - 1.6 8.3 7.0 0.92 9.1 2.5 2.5 1 1 1 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Shisa PF13908.6 CRK11429.1 - 3 8.1 9.4 0.52 10.5 0.2 2.5 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator XFP_N PF09364.10 CRK11431.1 - 1.1e-143 478.5 0.0 1.4e-143 478.1 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.10 CRK11431.1 - 8.1e-76 254.0 0.0 1.3e-75 253.3 0.0 1.3 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.15 CRK11431.1 - 5.7e-63 211.8 0.0 8.2e-63 211.3 0.0 1.2 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase TPP_enzyme_C PF02775.21 CRK11431.1 - 0.00058 19.7 0.1 0.0041 16.9 0.1 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Catalase PF00199.19 CRK11434.1 - 5.1e-169 562.4 0.3 8.4e-169 561.7 0.3 1.3 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 CRK11434.1 - 6.3e-20 71.1 0.6 1.2e-19 70.3 0.6 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive Catalase_C PF18011.1 CRK11434.1 - 3.1e-10 39.9 0.2 7.9e-10 38.6 0.2 1.7 1 1 0 1 1 1 1 C-terminal domain found in long catalases DJ-1_PfpI PF01965.24 CRK11434.1 - 3.2e-07 30.3 0.0 5.5e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family Fungal_trans PF04082.18 CRK11436.1 - 4.8e-23 81.5 0.1 8.1e-23 80.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK11436.1 - 3.3e-06 27.1 14.0 6.1e-06 26.3 14.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Haem_oxygenas_2 PF14518.6 CRK11436.1 - 0.0069 16.2 0.3 0.017 14.9 0.3 1.7 1 0 0 1 1 1 1 Iron-containing redox enzyme NFACT-R_1 PF05670.13 CRK11438.1 - 2.7e-38 131.0 0.0 3.9e-38 130.4 0.0 1.2 1 0 0 1 1 1 1 NFACT protein RNA binding domain HeLo PF14479.6 CRK11440.1 - 1.3e-08 35.0 0.1 0.0044 16.9 0.0 2.5 1 1 1 2 2 2 2 Prion-inhibition and propagation Roughex PF06020.11 CRK11440.1 - 0.47 9.5 2.1 9.5 5.2 1.6 2.2 2 0 0 2 2 2 0 Drosophila roughex protein Pec_lyase_C PF00544.19 CRK11441.1 - 2.1e-12 47.1 9.9 1.5e-10 41.0 9.9 2.2 1 1 0 1 1 1 1 Pectate lyase DUF4552 PF15089.6 CRK11441.1 - 0.096 11.7 0.1 0.15 11.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4552) RINGv PF12906.7 CRK11446.1 - 3.1e-17 62.4 8.5 5.4e-17 61.7 8.5 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 CRK11446.1 - 0.0048 17.2 9.0 0.0081 16.5 9.0 1.4 1 0 0 1 1 1 1 Ring finger domain DUF4834 PF16118.5 CRK11446.1 - 0.24 12.4 0.0 0.24 12.4 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) zf-ANAPC11 PF12861.7 CRK11446.1 - 0.45 10.6 2.2 1.2 9.2 2.2 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 CRK11446.1 - 1 9.2 5.5 2 8.4 5.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 CRK11446.1 - 3.4 7.9 4.9 6.8 7.0 4.9 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain Tom5 PF10642.9 CRK11446.1 - 6.2 6.9 7.4 4.2 7.5 0.6 3.0 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase tRNA-synt_1d PF00750.19 CRK11450.1 - 9.6e-100 333.9 4.8 1.6e-99 333.2 4.8 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 CRK11450.1 - 1.6e-30 105.7 0.4 4.1e-30 104.4 0.4 1.8 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 CRK11450.1 - 0.00057 20.4 0.0 0.0017 18.9 0.0 1.9 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain Sugar_tr PF00083.24 CRK11453.1 - 3.2e-65 220.8 21.1 4.2e-65 220.4 21.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK11453.1 - 2.5e-15 56.3 25.1 2.5e-15 56.3 25.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.18 CRK11456.1 - 2.2e-10 40.5 9.0 3.7e-10 39.8 9.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 CRK11456.1 - 2.7e-06 26.6 0.2 4.6e-06 25.9 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.25 CRK11458.1 - 7.8e-27 94.0 2.0 4.4e-18 65.5 0.6 3.0 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CRK11458.1 - 5.4e-22 78.5 2.2 3.4e-13 49.7 0.4 2.9 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK11458.1 - 4.7e-06 26.6 0.0 1e-05 25.6 0.0 1.7 1 1 0 1 1 1 1 KR domain Oxidored_FMN PF00724.20 CRK11458.1 - 0.042 13.1 0.1 0.061 12.6 0.1 1.2 1 0 0 1 1 1 0 NADH:flavin oxidoreductase / NADH oxidase family HET PF06985.11 CRK11460.1 - 4.5e-29 101.7 0.0 7.8e-29 100.9 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Aminotran_4 PF01063.19 CRK11461.1 - 7.3e-27 94.7 0.0 1.2e-26 93.9 0.0 1.4 1 0 0 1 1 1 1 Amino-transferase class IV ADH_zinc_N PF00107.26 CRK11461.1 - 6e-10 39.2 0.1 1.6e-09 37.8 0.1 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase YCII PF03795.14 CRK11461.1 - 1.1e-07 32.1 0.1 2.7e-07 30.9 0.1 1.6 1 0 0 1 1 1 1 YCII-related domain ADH_N PF08240.12 CRK11461.1 - 4.8e-05 23.2 0.1 0.00013 21.8 0.1 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 CRK11461.1 - 7.1e-05 23.9 0.0 0.00032 21.8 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AATase PF07247.12 CRK11461.1 - 0.021 13.4 0.0 0.031 12.8 0.0 1.1 1 0 0 1 1 1 0 Alcohol acetyltransferase BCIP PF13862.6 CRK11535.1 - 4.6e-32 111.5 0.0 5.9e-32 111.1 0.0 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein Mannosyl_trans2 PF04188.13 CRK11538.1 - 1.2e-51 176.5 6.4 4.9e-51 174.4 6.4 1.7 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V) DUF1996 PF09362.10 CRK11539.1 - 3.1e-32 112.5 0.0 3.9e-32 112.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Chitin_synth_2 PF03142.15 CRK11540.1 - 1.1e-41 143.1 0.3 9.9e-34 116.8 0.2 2.1 1 1 1 2 2 2 2 Chitin synthase Glycos_transf_2 PF00535.26 CRK11540.1 - 3.3e-10 40.1 0.1 3.1e-05 23.8 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 CRK11540.1 - 2.3e-08 34.2 4.5 2.3e-08 34.2 4.5 2.6 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 CRK11540.1 - 1.7e-06 28.1 0.4 0.001 19.0 0.1 2.7 2 1 0 2 2 2 2 Glycosyltransferase like family 2 UDPG_MGDP_dh PF00984.19 CRK11541.1 - 6.8e-20 71.1 0.0 1.5e-19 70.0 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_N PF03721.14 CRK11541.1 - 1.3e-15 57.5 0.0 4.5e-14 52.5 0.0 2.3 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.15 CRK11541.1 - 1.6e-06 28.3 0.0 2.5e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.18 CRK11541.1 - 0.00079 19.7 0.0 0.0034 17.6 0.0 2.1 2 0 0 2 2 2 1 TrkA-N domain UDPG_MGDP_dh_C PF03720.15 CRK11541.1 - 0.025 15.0 0.0 0.054 13.9 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Methyltransf_12 PF08242.12 CRK11541.1 - 0.057 14.2 0.1 0.34 11.7 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain adh_short PF00106.25 CRK11542.1 - 0.11 12.0 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase Pec_lyase_C PF00544.19 CRK11543.1 - 1.2e-40 139.4 2.2 1.8e-40 138.8 2.2 1.3 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 CRK11543.1 - 0.00092 19.1 8.4 0.0074 16.2 8.4 2.1 1 1 0 1 1 1 1 Right handed beta helix region BLM10_mid PF16507.5 CRK11544.1 - 2.2e-193 643.7 0.0 3.2e-193 643.2 0.0 1.2 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 CRK11544.1 - 5.3e-30 103.2 0.0 4.9e-29 100.1 0.0 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF3437) BLM10_N PF16547.5 CRK11544.1 - 2.5e-20 72.6 0.0 7e-20 71.1 0.0 1.9 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, N-terminal HEAT PF02985.22 CRK11544.1 - 0.0026 17.9 2.0 26 5.4 0.2 6.1 6 0 0 6 6 6 0 HEAT repeat RNase_J_C PF17770.1 CRK11544.1 - 0.057 14.5 0.0 0.3 12.2 0.0 2.3 2 0 0 2 2 2 0 Ribonuclease J C-terminal domain WAC_Acf1_DNA_bd PF10537.9 CRK11544.1 - 0.071 13.6 0.0 0.2 12.2 0.0 1.8 1 0 0 1 1 1 0 ATP-utilising chromatin assembly and remodelling N-terminal IFRD PF05004.13 CRK11544.1 - 0.1 11.7 0.0 6.7 5.7 0.0 2.4 2 0 0 2 2 2 0 Interferon-related developmental regulator (IFRD) NUC130_3NT PF08158.12 CRK11544.1 - 0.11 12.8 0.1 0.78 10.1 0.0 2.6 2 0 0 2 2 2 0 NUC130/3NT domain CorA PF01544.18 CRK11545.1 - 7.6e-38 130.5 0.2 1.1e-37 130.0 0.2 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein CHASE9 PF17153.4 CRK11545.1 - 0.19 11.9 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 Periplasmic sensor domain, extracellular Peptidase_M91 PF14891.6 CRK11546.1 - 0.12 12.6 0.1 0.17 12.2 0.1 1.3 1 0 0 1 1 1 0 Effector protein NAM-associated PF14303.6 CRK11547.1 - 0.52 11.0 11.4 0.63 10.8 11.4 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain CDH-cyt PF16010.5 CRK11549.1 - 7.4e-49 165.9 3.5 1.3e-48 165.1 3.5 1.4 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase GMC_oxred_N PF00732.19 CRK11549.1 - 3e-25 89.2 0.0 6e-25 88.2 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CRK11549.1 - 1e-23 84.4 0.1 2e-23 83.5 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase CBM_1 PF00734.18 CRK11549.1 - 4.4e-11 42.5 3.3 4.4e-11 42.5 3.3 2.2 2 0 0 2 2 1 1 Fungal cellulose binding domain FAD_binding_2 PF00890.24 CRK11549.1 - 8.7e-09 35.0 0.9 5.5e-08 32.3 0.9 1.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 CRK11549.1 - 3.2e-05 24.1 1.6 7.4e-05 22.9 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CRK11549.1 - 0.00036 19.9 0.0 0.00077 18.8 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CRK11549.1 - 0.0044 17.5 0.0 0.93 10.1 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CRK11549.1 - 0.0083 15.2 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 CRK11549.1 - 0.012 14.4 0.0 0.02 13.6 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 CRK11549.1 - 0.029 13.6 0.1 0.048 12.9 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 CRK11549.1 - 0.042 13.1 0.1 0.23 10.7 0.1 2.0 2 0 0 2 2 2 0 Thi4 family FAD_oxidored PF12831.7 CRK11549.1 - 0.046 13.1 0.0 1.1 8.5 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 CRK11549.1 - 0.066 12.4 1.5 0.14 11.4 0.5 2.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Lactamase_B_2 PF12706.7 CRK11551.1 - 2e-09 37.3 0.0 3.8e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 CRK11551.1 - 0.00032 20.8 0.0 0.00082 19.4 0.0 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily DRMBL PF07522.14 CRK11551.1 - 0.015 15.5 0.0 0.04 14.1 0.0 1.8 1 0 0 1 1 1 0 DNA repair metallo-beta-lactamase DUF1479 PF07350.12 CRK11552.1 - 1.2e-146 488.8 0.0 1.5e-146 488.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) Ank_2 PF12796.7 CRK11553.1 - 1.1e-66 221.4 9.4 9e-17 61.4 0.1 6.6 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CRK11553.1 - 1.3e-44 149.9 4.9 3.3e-10 40.3 0.0 8.6 5 2 4 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 CRK11553.1 - 3.7e-38 125.2 7.2 0.00012 22.3 0.0 11.5 12 0 0 12 12 12 7 Ankyrin repeat Ank PF00023.30 CRK11553.1 - 1.2e-32 110.9 18.2 1.2e-06 28.7 0.0 10.3 11 0 0 11 11 11 6 Ankyrin repeat Ank_5 PF13857.6 CRK11553.1 - 1.4e-26 92.2 17.4 6.6e-08 32.7 0.2 8.7 4 4 7 11 11 11 9 Ankyrin repeats (many copies) ANAPC5 PF12862.7 CRK11553.1 - 0.1 12.7 0.2 1.5 8.9 0.2 2.7 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 5 Ank_2 PF12796.7 CRK11554.1 - 4e-59 197.2 0.7 2.1e-11 44.2 0.0 6.5 5 1 0 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CRK11554.1 - 6.4e-45 151.0 5.1 7.1e-06 26.5 0.0 12.0 5 5 8 14 14 14 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 CRK11554.1 - 4.3e-43 140.3 9.6 0.015 15.8 0.0 15.2 16 0 0 16 16 16 11 Ankyrin repeat Ank PF00023.30 CRK11554.1 - 8.4e-36 120.9 13.9 0.01 16.2 0.0 14.7 14 1 0 14 14 14 11 Ankyrin repeat Ank_5 PF13857.6 CRK11554.1 - 1e-35 121.3 14.3 0.00013 22.2 0.0 10.7 7 3 4 11 11 11 10 Ankyrin repeats (many copies) Ldh_2 PF02615.14 CRK11555.1 - 1.2e-124 415.9 2.0 1.4e-124 415.6 2.0 1.1 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Fungal_trans PF04082.18 CRK11556.1 - 1.8e-28 99.3 0.7 3.5e-28 98.4 0.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain PT PF04886.12 CRK11556.1 - 1.6 8.3 8.9 3.8 7.1 8.9 1.6 1 0 0 1 1 1 0 PT repeat Dabb PF07876.12 CRK11557.1 - 4.1e-12 46.5 0.1 5.9e-12 46.1 0.1 1.2 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain adh_short_C2 PF13561.6 CRK11558.1 - 9.8e-55 185.6 3.1 1.8e-52 178.3 3.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRK11558.1 - 7.1e-41 139.8 1.3 9e-41 139.5 1.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CRK11558.1 - 0.00046 20.2 0.2 0.0007 19.6 0.2 1.2 1 0 0 1 1 1 1 KR domain DUF3288 PF11691.8 CRK11558.1 - 0.058 13.4 0.0 0.095 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3288) ILVD_EDD PF00920.21 CRK11559.1 - 7.6e-157 523.0 1.1 8.7e-157 522.8 1.1 1.0 1 0 0 1 1 1 1 Dehydratase family HEAT PF02985.22 CRK11560.1 - 3.5e-19 67.3 5.6 0.00029 20.8 0.0 7.9 8 0 0 8 8 7 5 HEAT repeat HEAT_EZ PF13513.6 CRK11560.1 - 4.1e-19 68.7 12.6 4.2e-09 36.7 0.0 8.8 9 1 1 10 10 8 3 HEAT-like repeat HEAT_2 PF13646.6 CRK11560.1 - 4.8e-16 58.9 16.5 1.2e-05 25.6 0.8 8.3 6 2 3 9 9 9 4 HEAT repeats Cnd1 PF12717.7 CRK11560.1 - 1.1e-10 41.7 0.2 0.00022 21.3 0.0 4.4 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 CRK11560.1 - 9.5e-10 37.6 0.1 0.0034 16.0 0.0 5.0 3 2 1 4 4 4 1 Adaptin N terminal region CLASP_N PF12348.8 CRK11560.1 - 1.8e-09 37.5 0.1 0.014 15.0 0.0 4.4 5 0 0 5 5 5 2 CLASP N terminal Vac14_Fab1_bd PF12755.7 CRK11560.1 - 1.1e-07 32.4 0.0 0.0014 19.2 0.0 4.9 5 0 0 5 5 4 1 Vacuolar 14 Fab1-binding region RIX1 PF08167.12 CRK11560.1 - 5.1e-07 29.6 1.2 0.036 13.8 0.0 4.3 4 1 0 4 4 4 2 rRNA processing/ribosome biogenesis IFRD PF05004.13 CRK11560.1 - 1.8e-05 24.0 4.0 0.27 10.3 0.0 4.0 3 1 0 4 4 4 2 Interferon-related developmental regulator (IFRD) IBN_N PF03810.19 CRK11560.1 - 2.6e-05 24.1 2.8 0.00012 21.9 0.7 3.2 3 0 0 3 3 3 1 Importin-beta N-terminal domain ParcG PF10274.9 CRK11560.1 - 0.00048 20.3 1.2 1.1 9.4 0.0 4.5 4 2 1 5 5 5 1 Parkin co-regulated protein Arm PF00514.23 CRK11560.1 - 0.0011 19.0 7.6 3.7 7.7 0.0 7.7 9 0 0 9 9 9 1 Armadillo/beta-catenin-like repeat MMS19_C PF12460.8 CRK11560.1 - 0.0012 18.1 1.4 0.0052 15.9 0.1 2.8 3 1 0 3 3 3 1 RNAPII transcription regulator C-terminal UME PF08064.13 CRK11560.1 - 0.0022 17.8 0.0 1.9 8.5 0.0 4.4 4 0 0 4 4 4 1 UME (NUC010) domain RTP1_C1 PF10363.9 CRK11560.1 - 0.011 15.9 3.2 3 8.1 0.1 4.0 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF3385 PF11865.8 CRK11560.1 - 0.013 15.4 0.1 15 5.4 0.0 4.5 3 2 1 4 4 4 0 Domain of unknown function (DUF3385) Dopey_N PF04118.14 CRK11560.1 - 0.12 11.4 1.3 7.6 5.5 0.0 3.1 3 1 0 3 3 3 0 Dopey, N-terminal Importin_rep_4 PF18808.1 CRK11560.1 - 4.7 7.6 10.3 6.9 7.0 0.1 4.7 5 0 0 5 5 4 0 Importin repeat HTH_IclR PF09339.10 CRK11561.1 - 0.086 12.7 1.6 0.22 11.4 1.2 1.9 1 1 1 2 2 2 0 IclR helix-turn-helix domain Sugar_tr PF00083.24 CRK11563.1 - 3.3e-81 273.4 20.4 3.9e-81 273.2 20.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK11563.1 - 1.1e-18 67.3 23.8 5.8e-18 64.9 18.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Alpha-amylase PF00128.24 CRK11564.1 - 2.4e-106 356.1 0.0 4.6e-106 355.2 0.0 1.4 2 0 0 2 2 2 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 CRK11564.1 - 0.00017 20.8 0.0 0.00032 19.9 0.0 1.3 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain Malt_amylase_C PF16657.5 CRK11564.1 - 0.008 16.3 0.0 0.02 15.0 0.0 1.7 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain Fungal_trans PF04082.18 CRK11565.1 - 0.0013 17.8 0.6 0.012 14.7 0.6 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK11565.1 - 0.0068 16.5 8.7 0.011 15.9 8.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NUDE_C PF04880.13 CRK11565.1 - 0.64 10.5 3.3 3.1 8.3 0.0 2.4 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region zf-U1 PF06220.12 CRK11566.1 - 6.9e-06 25.7 0.2 1.2e-05 25.0 0.2 1.4 1 0 0 1 1 1 1 U1 zinc finger Sugar_tr PF00083.24 CRK11569.1 - 3.3e-82 276.8 20.9 3.7e-82 276.6 20.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK11569.1 - 1.4e-28 99.8 19.4 2e-28 99.4 19.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 CRK11569.1 - 6.9e-07 28.2 11.7 4.1e-06 25.6 2.2 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein PTR2 PF00854.21 CRK11569.1 - 0.00051 19.0 2.8 0.00051 19.0 2.8 2.2 2 0 0 2 2 2 1 POT family DUF4441 PF14536.6 CRK11569.1 - 0.018 15.2 0.0 0.044 14.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4441) ADH_zinc_N PF00107.26 CRK11570.1 - 9.5e-08 32.1 1.2 1.3e-07 31.7 0.2 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CRK11570.1 - 0.00015 21.6 0.0 0.00025 20.9 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 CRK11570.1 - 0.011 16.8 0.0 0.045 14.8 0.0 1.9 2 0 0 2 2 2 0 Zinc-binding dehydrogenase DUF2374 PF09574.10 CRK11570.1 - 0.082 12.7 0.8 0.17 11.8 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (Duf2374) Peptidase_M14 PF00246.24 CRK11571.1 - 8.2e-33 114.4 0.0 1e-32 114.1 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase RVT_1 PF00078.27 CRK11572.1 - 0.00066 19.3 0.0 0.0013 18.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Dynamin_M PF01031.20 CRK11573.1 - 2.2e-18 66.5 0.7 2.3e-08 33.6 0.1 2.3 2 0 0 2 2 2 2 Dynamin central region Dynamin_N PF00350.23 CRK11573.1 - 3e-17 63.2 0.0 1.5e-16 60.9 0.0 2.2 1 1 0 1 1 1 1 Dynamin family GED PF02212.18 CRK11573.1 - 0.00018 21.6 0.1 0.00053 20.1 0.1 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain Nuc_sug_transp PF04142.15 CRK11574.1 - 5.5e-70 236.0 9.9 1e-69 235.1 9.9 1.4 1 1 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 CRK11574.1 - 8.6e-07 28.5 7.0 8.9e-07 28.4 1.8 2.0 2 0 0 2 2 2 1 UAA transporter family EamA PF00892.20 CRK11574.1 - 4.7e-05 23.6 23.4 0.009 16.2 2.8 2.3 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 CRK11574.1 - 0.00052 19.4 11.3 0.0012 18.3 3.9 2.1 2 0 0 2 2 2 2 Triose-phosphate Transporter family Sec63 PF02889.16 CRK11575.1 - 5.3e-05 22.5 0.0 7.8e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DUF4332 PF14229.6 CRK11575.1 - 0.00059 20.1 0.1 0.0038 17.4 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4332) TfoX_C PF04994.13 CRK11575.1 - 0.0017 18.4 0.0 0.0031 17.6 0.0 1.4 1 0 0 1 1 1 1 TfoX C-terminal domain HHH_5 PF14520.6 CRK11575.1 - 0.013 16.1 0.0 0.039 14.6 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain Cdd1 PF11731.8 CRK11575.1 - 0.19 12.0 0.0 0.34 11.2 0.0 1.3 1 0 0 1 1 1 0 Pathogenicity locus DCB PF16213.5 CRK11576.1 - 3.7e-48 163.5 7.4 6.4e-47 159.5 6.2 2.9 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 CRK11576.1 - 4.8e-43 146.8 4.0 1.4e-41 142.0 0.1 3.9 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Mon2_C PF16206.5 CRK11576.1 - 2.8e-28 98.6 2.2 6.7e-23 80.8 1.1 3.6 3 1 1 4 4 4 3 C-terminal region of Mon2 protein DUF1981 PF09324.10 CRK11576.1 - 4.4e-05 23.2 0.4 0.0018 18.1 0.0 3.6 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) NRDE-2 PF08424.10 CRK11576.1 - 0.11 11.6 0.2 0.34 10.0 0.1 1.8 2 0 0 2 2 2 0 NRDE-2, necessary for RNA interference Band_7 PF01145.25 CRK11577.1 - 1.7e-30 106.3 0.4 3.2e-30 105.4 0.4 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_C PF16200.5 CRK11577.1 - 1.4e-23 82.7 2.8 2e-23 82.2 1.4 2.1 2 0 0 2 2 2 1 C-terminal region of band_7 Pox_A11 PF05061.13 CRK11577.1 - 0.017 14.4 0.3 0.027 13.8 0.3 1.3 1 0 0 1 1 1 0 Poxvirus A11 Protein GSH-S_N PF02951.14 CRK11577.1 - 0.1 12.8 0.1 0.23 11.6 0.1 1.6 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, N-terminal domain Band_7_1 PF13421.6 CRK11577.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family Fungal_trans PF04082.18 CRK11579.1 - 2.4e-17 62.9 0.0 4e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK11579.1 - 7.2e-07 29.2 16.5 1.2e-06 28.5 16.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_88 PF07470.13 CRK11580.1 - 7.1e-06 25.3 0.2 0.00012 21.2 0.3 2.1 2 0 0 2 2 2 1 Glycosyl Hydrolase Family 88 DUF5473 PF17567.2 CRK11580.1 - 0.087 13.1 1.5 0.36 11.1 0.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5473) Transp_cyt_pur PF02133.15 CRK11581.1 - 2.4e-94 316.6 33.2 1.1e-93 314.4 33.2 1.8 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Amidase PF01425.21 CRK11582.1 - 3.2e-78 263.7 0.0 4e-78 263.4 0.0 1.1 1 0 0 1 1 1 1 Amidase Isochorismatase PF00857.20 CRK11582.1 - 3.9e-38 131.3 0.0 8.6e-38 130.2 0.0 1.6 1 0 0 1 1 1 1 Isochorismatase family Glyco_hydro_47 PF01532.20 CRK11584.1 - 2.9e-26 92.4 0.1 1.6e-18 66.9 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 47 Glyco_hydro_61 PF03443.14 CRK11585.1 - 1.2e-49 169.0 0.0 1.5e-49 168.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CPP1-like PF11833.8 CRK11586.1 - 0.099 12.3 3.3 0.1 12.3 2.1 1.5 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like YIF1 PF03878.15 CRK11587.1 - 2e-84 282.9 0.2 2.2e-84 282.7 0.2 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 CRK11587.1 - 8.4e-05 22.3 4.8 8.4e-05 22.3 4.8 1.5 2 0 0 2 2 2 1 Yip1 domain Proteasome PF00227.26 CRK11589.1 - 0.009 15.5 0.0 0.009 15.5 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Integrase_Zn PF02022.19 CRK11589.1 - 0.027 14.4 0.1 0.041 13.9 0.1 1.3 1 0 0 1 1 1 0 Integrase Zinc binding domain Glyco_hydro_16 PF00722.21 CRK11591.1 - 9.2e-16 57.8 1.6 1.3e-15 57.3 1.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 TaqI_C PF12950.7 CRK11591.1 - 0.081 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 TaqI-like C-terminal specificity domain Ribosomal_L14 PF00238.19 CRK11614.1 - 3.6e-15 56.1 0.0 4.1e-15 55.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e PHO4 PF01384.20 CRK11641.1 - 1.8e-40 139.0 16.5 2.1e-40 138.8 16.5 1.1 1 0 0 1 1 1 1 Phosphate transporter family TauD PF02668.16 CRK11642.1 - 3.3e-10 40.2 0.0 3.6e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Folate_carrier PF01770.18 CRK11649.1 - 0.00073 18.4 1.6 0.00095 18.0 1.6 1.1 1 0 0 1 1 1 1 Reduced folate carrier Na_Ca_ex PF01699.24 CRK11650.1 - 4.7e-27 94.8 20.0 4.8e-14 52.6 9.1 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF2206 PF09971.9 CRK11650.1 - 0.032 13.0 0.8 0.75 8.5 0.0 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2206) DUF4337 PF14235.6 CRK11650.1 - 0.17 12.0 0.9 0.51 10.4 0.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) MLANA PF14991.6 CRK11650.1 - 0.29 11.4 0.6 3.6 7.9 0.1 2.7 2 0 0 2 2 2 0 Protein melan-A Beta_propel PF09826.9 CRK11651.1 - 0.17 10.7 0.7 1.2 7.9 0.0 2.0 1 1 0 2 2 2 0 Beta propeller domain SLAC1 PF03595.17 CRK11656.1 - 1.7e-81 274.0 44.1 2e-81 273.8 44.1 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel CBM-like PF14683.6 CRK11658.1 - 7.5e-36 123.5 0.1 2.1e-35 122.1 0.1 1.8 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 CRK11658.1 - 5e-12 45.4 0.6 1.7e-11 43.8 0.6 2.0 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 CRK11658.1 - 2.7e-08 34.0 1.9 6.3e-08 32.8 0.3 2.5 3 0 0 3 3 3 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 CRK11658.1 - 0.026 14.5 1.2 0.14 12.1 0.7 2.4 2 0 0 2 2 2 0 CarboxypepD_reg-like domain DUF2012 PF09430.10 CRK11658.1 - 0.07 13.2 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2012) Esterase_phd PF10503.9 CRK11659.1 - 1.3e-23 83.6 2.1 1.3e-23 83.6 2.1 1.7 2 0 0 2 2 2 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 CRK11659.1 - 3.4e-13 49.5 1.7 5.1e-13 49.0 1.7 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family CBM_1 PF00734.18 CRK11659.1 - 1.1e-12 47.7 11.0 4.4e-12 45.7 11.0 2.2 1 0 0 1 1 1 1 Fungal cellulose binding domain Abhydrolase_3 PF07859.13 CRK11659.1 - 0.001 19.0 0.1 0.0017 18.3 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 CRK11659.1 - 0.024 14.3 0.1 0.039 13.6 0.1 1.3 1 0 0 1 1 1 0 Putative esterase Abhydrolase_2 PF02230.16 CRK11659.1 - 0.038 13.8 0.1 0.079 12.8 0.1 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase COesterase PF00135.28 CRK11659.1 - 0.046 12.6 0.7 0.079 11.8 0.7 1.3 1 0 0 1 1 1 0 Carboxylesterase family DLH PF01738.18 CRK11659.1 - 0.089 12.3 0.3 0.16 11.5 0.3 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family BAAT_C PF08840.11 CRK11659.1 - 0.11 12.4 0.2 0.18 11.7 0.2 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.20 CRK11659.1 - 0.15 11.7 1.8 0.52 9.9 0.7 2.0 1 1 0 2 2 2 0 alpha/beta hydrolase fold FSH1 PF03959.13 CRK11659.1 - 0.16 11.6 0.1 0.63 9.7 0.1 1.8 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 CRK11659.1 - 0.19 10.9 0.1 1.7 7.8 0.1 2.0 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Orthopox_A5L PF06193.11 CRK11659.1 - 7.1 6.0 14.3 11 5.3 14.3 1.2 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like Glyco_hydro_31 PF01055.26 CRK11662.1 - 9.5e-94 315.1 0.0 1.3e-93 314.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 CRK11662.1 - 1.8e-12 47.4 0.0 6.4e-12 45.6 0.0 2.0 1 0 0 1 1 1 1 Galactose mutarotase-like APH PF01636.23 CRK11662.1 - 0.014 15.3 0.1 0.034 14.1 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 CRK11662.1 - 0.021 14.2 0.0 0.036 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Kdo PF06293.14 CRK11662.1 - 0.025 13.9 0.0 0.046 13.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WaaY PF06176.11 CRK11662.1 - 0.2 11.2 0.0 0.34 10.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) adh_short PF00106.25 CRK11663.1 - 1.6e-32 112.5 0.0 2.1e-32 112.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK11663.1 - 1.4e-30 106.6 0.1 1.7e-30 106.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase CRAL_TRIO PF00650.20 CRK11664.1 - 9.4e-24 83.9 0.0 1.3e-23 83.5 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CRK11664.1 - 2.6e-08 33.9 0.0 6.3e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Acid_PPase PF12689.7 CRK11665.1 - 5.5e-61 205.3 0.0 6.5e-61 205.1 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase SSXRD PF09514.10 CRK11665.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 SSXRD motif CBM_1 PF00734.18 CRK11666.1 - 3.3e-11 42.9 9.2 1.2e-10 41.2 9.2 2.1 1 0 0 1 1 1 1 Fungal cellulose binding domain Toxin_7 PF05980.12 CRK11666.1 - 0.047 13.9 0.4 0.13 12.6 0.4 1.7 1 0 0 1 1 1 0 Toxin 7 Ank_4 PF13637.6 CRK11667.1 - 1.6e-14 54.0 0.2 0.0014 19.2 0.0 5.4 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 CRK11667.1 - 6.6e-10 39.5 0.1 0.0049 17.4 0.0 5.0 4 2 2 6 6 6 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CRK11667.1 - 7.6e-07 29.3 0.2 2.2 8.7 0.0 4.7 4 1 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CRK11667.1 - 4.3e-06 26.7 0.3 13 6.7 0.0 6.5 6 0 0 6 6 6 1 Ankyrin repeat Ank PF00023.30 CRK11667.1 - 2.8e-05 24.3 3.3 0.15 12.6 0.1 5.3 6 0 0 6 6 6 1 Ankyrin repeat IL13 PF03487.13 CRK11667.1 - 0.031 14.0 0.1 0.073 12.9 0.1 1.5 1 0 0 1 1 1 0 Interleukin-13 Ank_4 PF13637.6 CRK11668.1 - 2.5e-14 53.5 0.2 0.001 19.6 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 CRK11668.1 - 1.6e-09 38.2 0.0 0.23 12.1 0.0 5.2 4 1 1 5 5 5 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CRK11668.1 - 2.5e-06 27.6 0.1 3.4 8.1 0.0 4.5 6 0 0 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CRK11668.1 - 2e-05 24.6 1.0 53 4.9 0.0 6.6 6 0 0 6 6 6 0 Ankyrin repeat Ank PF00023.30 CRK11668.1 - 0.0017 18.7 3.3 54 4.5 0.0 5.7 6 0 0 6 6 6 0 Ankyrin repeat IL13 PF03487.13 CRK11668.1 - 0.0022 17.8 0.3 0.0047 16.7 0.3 1.5 1 0 0 1 1 1 1 Interleukin-13 PAS_9 PF13426.7 CRK11669.1 - 1.6e-12 47.6 0.0 2e-11 44.0 0.0 2.2 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 CRK11669.1 - 0.00062 20.0 0.1 0.0064 16.7 0.0 2.5 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.12 CRK11669.1 - 0.15 12.4 0.0 0.32 11.3 0.0 1.6 1 0 0 1 1 1 0 PAS fold Stig1 PF04885.13 CRK11670.1 - 0.0011 19.4 9.2 0.0011 19.4 9.2 27.1 20 9 8 33 33 33 8 Stigma-specific protein, Stig1 p450 PF00067.22 CRK11671.1 - 2.1e-49 168.6 0.0 2.5e-49 168.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4904 PF16247.5 CRK11671.1 - 0.036 13.9 0.0 0.065 13.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4904) R3H-assoc PF13902.6 CRK11672.1 - 5.8e-18 65.6 0.9 1e-17 64.8 0.9 1.4 1 0 0 1 1 1 1 R3H-associated N-terminal domain R3H PF01424.22 CRK11672.1 - 0.00054 19.9 0.0 0.0055 16.7 0.0 2.3 2 0 0 2 2 2 1 R3H domain Peptidase_M14 PF00246.24 CRK11673.1 - 4.2e-67 227.0 0.0 5.5e-67 226.6 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase VirB3 PF05101.13 CRK11674.1 - 0.3 11.3 4.0 0.14 12.5 1.6 1.6 2 0 0 2 2 2 0 Type IV secretory pathway, VirB3-like protein Acetyltransf_7 PF13508.7 CRK11675.1 - 7.6e-10 39.1 0.0 0.0024 18.2 0.0 2.8 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CRK11675.1 - 8.4e-08 32.4 0.3 0.023 14.8 0.0 3.0 3 0 0 3 3 3 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CRK11675.1 - 1e-06 29.0 0.0 0.093 13.0 0.0 2.8 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_13 PF13880.6 CRK11675.1 - 5.3e-05 23.1 0.0 0.58 10.2 0.0 2.9 2 1 0 2 2 2 2 ESCO1/2 acetyl-transferase Acetyltransf_10 PF13673.7 CRK11675.1 - 5.6e-05 23.1 0.0 0.47 10.4 0.0 2.6 3 0 0 3 3 3 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CRK11675.1 - 0.00066 19.8 0.1 2.1 8.6 0.0 2.5 2 0 0 2 2 2 2 GCN5-related N-acetyl-transferase FR47 PF08445.10 CRK11675.1 - 0.0018 18.2 0.0 3 7.9 0.0 2.5 2 0 0 2 2 2 2 FR47-like protein DUF3143 PF11341.8 CRK11675.1 - 0.0025 18.1 0.5 4.2 7.8 0.1 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF3143) Acetyltransf_15 PF17013.5 CRK11675.1 - 0.0045 16.5 0.0 3 7.2 0.0 2.1 2 0 0 2 2 2 2 Putative acetyl-transferase Cpn60_TCP1 PF00118.24 CRK11676.1 - 4.1e-125 418.2 10.4 5e-125 417.9 10.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PAS_9 PF13426.7 CRK11677.1 - 3.9e-11 43.1 0.0 3.5e-10 40.1 0.0 2.1 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 CRK11677.1 - 0.0017 18.6 0.1 0.012 15.9 0.0 2.3 2 0 0 2 2 2 1 PAS fold p450 PF00067.22 CRK11678.1 - 4.6e-37 127.8 0.0 1.7e-20 73.2 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 Stig1 PF04885.13 CRK11678.1 - 0.00061 20.3 8.0 0.00061 20.3 8.0 27.7 23 8 8 33 33 33 10 Stigma-specific protein, Stig1 R3H-assoc PF13902.6 CRK11679.1 - 5.2e-18 65.7 0.9 1e-17 64.8 0.9 1.5 1 0 0 1 1 1 1 R3H-associated N-terminal domain R3H PF01424.22 CRK11679.1 - 0.00054 19.9 0.0 0.0056 16.7 0.0 2.3 2 0 0 2 2 2 1 R3H domain Peptidase_M14 PF00246.24 CRK11680.1 - 3.7e-66 223.9 0.0 4.7e-66 223.5 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Cpn60_TCP1 PF00118.24 CRK11683.1 - 4.3e-09 35.5 0.0 4.4e-09 35.5 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family tRNA-synt_2b PF00587.25 CRK11684.1 - 1.3e-20 74.2 0.0 1.7e-20 73.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) MMS1_N PF10433.9 CRK11685.1 - 2e-112 376.4 0.1 2.6e-112 375.9 0.1 1.1 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term DJ-1_PfpI PF01965.24 CRK11685.1 - 4.5e-09 36.3 0.0 1.1e-08 35.1 0.0 1.6 1 0 0 1 1 1 1 DJ-1/PfpI family Rieske PF00355.26 CRK11685.1 - 7.6e-09 35.4 0.1 1.7e-08 34.3 0.1 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Acetyltransf_1 PF00583.25 CRK11685.1 - 3.2e-08 33.8 0.0 6.6e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CRK11685.1 - 8.4e-07 29.3 0.0 2e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CRK11685.1 - 4.9e-06 26.5 0.0 1.1e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain COesterase PF00135.28 CRK11686.1 - 2.9e-79 267.3 0.0 3.8e-79 266.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CRK11686.1 - 6.2e-09 36.0 0.2 5.2e-08 33.0 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CRK11686.1 - 0.003 17.1 3.3 0.041 13.3 2.4 2.1 1 1 1 2 2 2 1 Prolyl oligopeptidase family peroxidase PF00141.23 CRK11687.1 - 1.7e-29 103.1 0.0 2.8e-29 102.4 0.0 1.3 1 0 0 1 1 1 1 Peroxidase PQ-loop PF04193.14 CRK11688.1 - 4.4e-19 68.0 5.4 1.2e-11 44.2 0.7 3.5 3 1 1 4 4 4 2 PQ loop repeat DUF3087 PF11286.8 CRK11688.1 - 0.12 11.8 2.4 0.26 10.8 2.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) SLATT_1 PF18181.1 CRK11688.1 - 4 7.4 5.9 14 5.6 3.0 2.4 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 adh_short PF00106.25 CRK11689.1 - 4.3e-32 111.1 0.9 5.6e-30 104.3 0.9 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK11689.1 - 1.6e-20 73.7 0.4 6.5e-18 65.2 0.4 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK11689.1 - 0.00041 20.3 0.9 0.0055 16.6 0.9 2.1 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 CRK11689.1 - 0.027 14.4 0.2 0.046 13.6 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 CRK11689.1 - 0.029 13.8 0.0 0.051 12.9 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 CRK11689.1 - 0.035 13.4 0.1 0.063 12.6 0.1 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain PGI PF00342.19 CRK11690.1 - 2.1e-91 306.9 0.0 2.9e-91 306.5 0.0 1.1 1 0 0 1 1 1 1 Phosphoglucose isomerase Pkinase PF00069.25 CRK11690.1 - 5.2e-69 232.5 0.0 7e-69 232.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK11690.1 - 3e-33 115.2 0.0 4.2e-33 114.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 CRK11690.1 - 6.2e-12 46.0 3.1 6.2e-12 46.0 3.1 1.9 2 0 0 2 2 2 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 CRK11690.1 - 1.4e-05 24.3 0.1 2e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CRK11690.1 - 0.011 15.1 0.0 0.025 13.9 0.0 1.5 1 1 0 1 1 1 0 Kinase-like Kdo PF06293.14 CRK11690.1 - 0.18 11.1 0.1 0.34 10.2 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mannitol_dh_C PF08125.13 CRK11691.1 - 1.6e-39 135.9 0.1 2.3e-39 135.4 0.1 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 CRK11691.1 - 1.8e-18 67.1 1.2 6.1e-18 65.4 0.1 2.2 2 1 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain UDPG_MGDP_dh_N PF03721.14 CRK11691.1 - 0.012 15.2 0.5 0.029 13.9 0.2 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 CRK11691.1 - 0.018 14.7 0.4 0.88 9.2 0.0 2.6 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Sacchrp_dh_NADP PF03435.18 CRK11691.1 - 0.08 13.2 0.3 4.6 7.5 0.0 2.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Coatomer_WDAD PF04053.14 CRK11692.1 - 4.3e-173 576.5 0.0 6.6e-172 572.5 0.0 2.1 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 CRK11692.1 - 6.4e-37 124.9 9.5 3.2e-06 27.8 0.0 8.6 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK11692.1 - 3e-07 30.6 0.1 5.2 7.4 0.0 5.7 4 1 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CRK11692.1 - 4.4e-05 22.3 3.7 0.037 12.7 0.1 3.8 2 2 1 3 3 3 3 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 CRK11692.1 - 0.1 12.7 0.0 7.2 6.7 0.0 3.7 3 2 1 4 4 4 0 Ciliary BBSome complex subunit 2, middle region ADH_zinc_N_2 PF13602.6 CRK11693.1 - 1.2e-24 87.9 0.0 2.1e-24 87.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 CRK11693.1 - 5.4e-10 39.4 0.3 1.5e-09 37.9 0.3 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CRK11693.1 - 3.3e-06 27.0 0.1 0.00017 21.4 0.0 3.0 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain DeoRC PF00455.22 CRK11693.1 - 0.0042 17.0 0.0 0.0094 15.9 0.0 1.5 1 0 0 1 1 1 1 DeoR C terminal sensor domain Zn_clus PF00172.18 CRK11695.1 - 4e-08 33.3 10.9 4e-08 33.3 10.9 3.2 2 1 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HATPase_c PF02518.26 CRK11698.1 - 5.1e-21 75.3 0.1 6.7e-21 74.9 0.1 1.3 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CRK11698.1 - 1.8e-05 24.6 0.0 2.2e-05 24.3 0.0 1.4 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HEAT PF02985.22 CRK11699.1 - 3.8e-06 26.7 0.6 0.026 14.8 0.0 2.5 2 0 0 2 2 2 2 HEAT repeat ABC_membrane PF00664.23 CRK11743.1 - 0.0017 18.1 0.0 0.0019 17.9 0.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region UT PF03253.14 CRK11743.1 - 0.015 14.4 0.1 0.017 14.3 0.1 1.2 1 0 0 1 1 1 0 Urea transporter DUF968 PF06147.11 CRK11743.1 - 0.073 13.3 0.0 0.09 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF968) ABC_tran PF00005.27 CRK11743.1 - 0.1 13.1 0.2 0.17 12.4 0.2 1.4 1 0 0 1 1 1 0 ABC transporter FAD_binding_8 PF08022.12 CRK11750.1 - 1.7e-13 50.6 0.1 3.4e-13 49.6 0.1 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 CRK11750.1 - 8.2e-13 48.6 0.8 8.2e-13 48.6 0.8 2.0 2 1 0 2 2 2 1 Ferric reductase like transmembrane component EF-hand_7 PF13499.6 CRK11750.1 - 0.00097 19.5 12.1 0.0066 16.9 1.4 2.1 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 CRK11750.1 - 0.015 15.2 1.4 0.043 13.8 1.4 1.8 1 0 0 1 1 1 0 EF-hand domain EF-hand_1 PF00036.32 CRK11750.1 - 0.02 14.4 1.8 0.062 12.9 1.8 1.9 1 0 0 1 1 1 0 EF hand SPARC_Ca_bdg PF10591.9 CRK11750.1 - 0.33 11.3 2.9 29 5.0 0.6 3.1 3 0 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region Pet100 PF09803.9 CRK11750.1 - 2.8 8.5 6.3 0.29 11.7 0.9 2.2 2 0 0 2 2 2 0 Pet100 GMC_oxred_C PF05199.13 CRK11751.1 - 3.5e-40 137.8 0.0 4.1e-40 137.6 0.0 1.0 1 0 0 1 1 1 1 GMC oxidoreductase Transthyretin PF00576.21 CRK11752.1 - 3.1e-38 130.8 0.0 5e-38 130.2 0.0 1.3 1 1 0 1 1 1 1 HIUase/Transthyretin family DAO PF01266.24 CRK11755.1 - 4.3e-17 62.7 0.4 5.9e-08 32.7 0.1 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CRK11755.1 - 0.00011 22.4 0.1 0.0019 18.4 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 CRK11755.1 - 0.04 13.9 0.1 0.078 13.0 0.0 1.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding Sacchrp_dh_NADP PF03435.18 CRK11755.1 - 0.057 13.7 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DUF3613 PF12266.8 CRK11755.1 - 0.13 12.0 1.3 0.24 11.2 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3613) Pyr_redox_2 PF07992.14 CRK11755.1 - 0.14 11.3 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TBP PF00352.21 CRK11756.1 - 1.3e-67 223.7 0.1 6.8e-33 112.5 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 CRK11756.1 - 0.00011 22.3 0.0 0.21 11.7 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 CRK11756.1 - 0.12 12.2 0.1 0.66 9.8 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) ETF_QO PF05187.13 CRK11757.1 - 2.3e-48 162.7 0.8 3.8e-48 161.9 0.8 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S DAO PF01266.24 CRK11757.1 - 2.9e-08 33.7 0.4 0.00011 21.9 0.3 2.5 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CRK11757.1 - 5.7e-08 32.9 0.0 2.8e-07 30.7 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CRK11757.1 - 6.9e-05 22.2 0.0 0.00027 20.2 0.0 1.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CRK11757.1 - 0.00019 21.9 0.0 0.49 11.0 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CRK11757.1 - 0.0002 20.2 0.4 0.00029 19.7 0.4 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 CRK11757.1 - 0.00023 20.4 0.3 0.011 14.8 0.6 2.2 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 CRK11757.1 - 0.00023 20.5 0.0 0.011 14.9 0.1 2.1 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.6 CRK11757.1 - 0.0025 17.8 0.1 0.0066 16.5 0.1 1.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding Trp_halogenase PF04820.14 CRK11757.1 - 0.0031 16.4 0.0 0.16 10.8 0.1 2.2 1 1 0 2 2 2 1 Tryptophan halogenase FAD_oxidored PF12831.7 CRK11757.1 - 0.0035 16.7 0.0 0.0058 16.0 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 CRK11757.1 - 0.0052 16.1 0.4 0.0078 15.5 0.4 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CRK11757.1 - 0.0076 15.5 0.1 0.013 14.7 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Fer4_7 PF12838.7 CRK11757.1 - 0.048 14.3 0.7 0.12 13.0 0.7 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain Lycopene_cycl PF05834.12 CRK11757.1 - 0.061 12.4 0.2 0.088 11.8 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 CRK11757.1 - 0.12 11.6 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Fer4_2 PF12797.7 CRK11757.1 - 0.12 12.5 0.6 0.34 11.1 0.6 1.7 1 0 0 1 1 1 0 4Fe-4S binding domain GIDA PF01134.22 CRK11757.1 - 0.15 11.1 0.1 0.24 10.5 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Glyco_hydro_92 PF07971.12 CRK11758.1 - 3.7e-126 421.8 0.0 1.4e-117 393.5 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 CRK11758.1 - 1.1e-64 218.5 0.0 1.6e-64 218.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain T5orf172 PF10544.9 CRK11759.1 - 1.7e-12 47.8 0.8 1.7e-12 47.8 0.8 2.4 2 0 0 2 2 2 1 T5orf172 domain MUG113 PF13455.6 CRK11759.1 - 2.9e-07 31.1 0.8 1e-06 29.3 0.8 2.0 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 PAN_4 PF14295.6 CRK11759.1 - 0.023 14.6 2.9 0.059 13.3 2.9 1.6 1 0 0 1 1 1 0 PAN domain Nop14 PF04147.12 CRK11759.1 - 2.4 6.3 16.5 4.5 5.4 16.5 1.4 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 CRK11759.1 - 5 5.3 15.4 7.7 4.7 15.4 1.2 1 0 0 1 1 1 0 CDC45-like protein T5orf172 PF10544.9 CRK11761.1 - 4.1e-13 49.7 0.1 8.4e-13 48.8 0.1 1.5 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 CRK11761.1 - 9.9e-07 29.4 0.1 1.9e-06 28.5 0.1 1.4 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 Aim21 PF11489.8 CRK11762.1 - 3.9e-178 594.7 81.2 3.9e-178 594.7 81.2 2.5 3 0 0 3 3 3 1 Altered inheritance of mitochondria protein 21 Cg6151-P PF10233.9 CRK11764.1 - 2.9e-43 146.8 16.3 3.4e-43 146.5 16.3 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P DUF308 PF03729.13 CRK11764.1 - 0.013 15.8 3.4 0.013 15.8 3.4 2.5 2 1 0 2 2 2 0 Short repeat of unknown function (DUF308) CitMHS PF03600.16 CRK11764.1 - 0.047 12.9 11.1 0.051 12.8 11.1 1.0 1 0 0 1 1 1 0 Citrate transporter Cation_ATPase_C PF00689.21 CRK11764.1 - 1.4 8.6 13.4 0.79 9.4 9.5 2.0 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus Cytochrom_B558a PF05038.13 CRK11764.1 - 1.4 8.5 7.5 5 6.7 7.0 2.1 1 1 1 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit Usp PF00582.26 CRK11765.1 - 1.6e-15 57.9 0.3 1.3e-13 51.7 0.1 2.7 2 0 0 2 2 2 1 Universal stress protein family F-box-like PF12937.7 CRK11765.1 - 5.2e-08 32.6 0.1 0.012 15.5 0.0 2.7 2 0 0 2 2 2 2 F-box-like F-box PF00646.33 CRK11765.1 - 3.8e-05 23.4 0.0 0.38 10.7 0.0 2.5 2 0 0 2 2 2 2 F-box domain DUF2721 PF11026.8 CRK11765.1 - 0.0023 17.8 0.5 18 5.3 0.1 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) DUF1664 PF07889.12 CRK11765.1 - 0.011 15.8 0.0 32 4.6 0.0 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) TruB_C_2 PF16198.5 CRK11765.1 - 0.035 14.2 0.3 19 5.5 0.0 3.0 2 0 0 2 2 2 0 tRNA pseudouridylate synthase B C-terminal domain KinB_sensor PF16767.5 CRK11765.1 - 0.056 13.9 4.3 5.1 7.6 0.2 2.8 2 0 0 2 2 2 0 Sensor domain of alginate biosynthesis sensor protein KinB Sigma70_r2 PF04542.14 CRK11765.1 - 0.1 12.4 1.0 18 5.2 0.1 2.7 2 0 0 2 2 2 0 Sigma-70 region 2 Bac_DNA_binding PF00216.21 CRK11765.1 - 0.16 12.2 0.2 36 4.7 0.0 2.6 2 0 0 2 2 2 0 Bacterial DNA-binding protein MNHE PF01899.16 CRK11765.1 - 0.19 11.5 3.7 9.8 5.9 0.3 2.6 2 0 0 2 2 2 0 Na+/H+ ion antiporter subunit AmiS_UreI PF02293.15 CRK11765.1 - 0.22 11.5 3.8 8 6.4 0.3 2.5 2 0 0 2 2 2 0 AmiS/UreI family transporter TPPK_C PF12555.8 CRK11765.1 - 6.3 6.9 6.8 28 4.8 0.7 2.8 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal Ribosomal_S7 PF00177.21 CRK11767.1 - 1.4e-26 92.9 0.8 2.3e-26 92.2 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S7p/S5e DUF2868 PF11067.8 CRK11767.1 - 1.4 8.3 6.7 1.3 8.5 5.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2868) RRM_1 PF00076.22 CRK11769.1 - 4.4e-39 132.1 2.2 3.4e-18 65.2 0.2 3.7 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_S7 PF00177.21 CRK11769.1 - 1.3e-25 89.8 1.2 1.9e-25 89.3 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein S7p/S5e RRM_occluded PF16842.5 CRK11769.1 - 8.4e-07 28.8 0.0 0.01 15.7 0.0 3.3 3 0 0 3 3 3 2 Occluded RNA-recognition motif YflT PF11181.8 CRK11769.1 - 7.1e-05 23.2 1.2 0.038 14.5 0.5 3.1 2 0 0 2 2 2 2 Heat induced stress protein YflT Nefa_Nip30_N PF10187.9 CRK11769.1 - 0.033 14.5 0.4 0.033 14.5 0.4 4.0 4 0 0 4 4 4 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 RRM_3 PF08777.11 CRK11769.1 - 0.17 11.9 7.7 0.38 10.8 1.4 3.3 2 1 0 3 3 3 0 RNA binding motif Nup35_RRM_2 PF14605.6 CRK11769.1 - 0.19 11.8 0.0 47 4.1 0.0 3.1 3 1 0 3 3 3 0 Nup53/35/40-type RNA recognition motif NMO PF03060.15 CRK11771.1 - 6e-15 55.4 0.1 6.7e-15 55.3 0.1 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 CRK11771.1 - 3.2e-06 26.4 0.0 3.2e-06 26.4 0.0 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NIL PF09383.10 CRK11771.1 - 0.064 13.1 0.0 0.073 12.9 0.0 1.2 1 0 0 1 1 1 0 NIL domain NMO PF03060.15 CRK11772.1 - 2.1e-55 188.5 0.6 1.6e-54 185.6 0.6 1.9 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 CRK11772.1 - 1e-12 47.8 0.4 6.6e-11 41.8 0.5 2.2 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 CRK11772.1 - 0.0015 17.6 0.2 0.0026 16.9 0.2 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase PABP PF00658.18 CRK11773.1 - 7.3e-25 86.9 1.8 1.5e-24 86.0 1.8 1.4 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain RRM_1 PF00076.22 CRK11773.1 - 2e-19 69.2 0.0 3.3e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NMO PF03060.15 CRK11774.1 - 1.5e-26 93.6 0.0 1.8e-26 93.4 0.0 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 CRK11774.1 - 9.4e-06 24.9 0.1 1.3e-05 24.4 0.1 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 CRK11774.1 - 0.0019 17.3 0.1 0.0025 16.9 0.1 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 CRK11774.1 - 0.05 13.1 0.0 0.12 11.9 0.0 1.6 2 0 0 2 2 2 0 Histidine biosynthesis protein Glu_synthase PF01645.17 CRK11774.1 - 0.12 11.5 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Conserved region in glutamate synthase DUF1902 PF08972.11 CRK11774.1 - 0.14 12.2 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1902) PABP PF00658.18 CRK11775.1 - 2.1e-24 85.5 1.8 4.2e-24 84.5 1.8 1.4 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain RRM_1 PF00076.22 CRK11775.1 - 2e-18 66.0 0.2 7.5e-08 32.1 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nefa_Nip30_N PF10187.9 CRK11775.1 - 0.021 15.2 0.4 0.021 15.2 0.4 2.6 2 1 0 2 2 2 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 DNA_pol_phi PF04931.13 CRK11775.1 - 0.57 8.2 7.2 0.98 7.4 7.2 1.3 1 0 0 1 1 1 0 DNA polymerase phi IQ PF00612.27 CRK11777.1 - 0.00015 21.2 14.5 0.065 13.1 3.4 2.8 2 0 0 2 2 2 2 IQ calmodulin-binding motif DUF3523 PF12037.8 CRK11777.1 - 1.7 7.9 11.3 3.2 7.1 2.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3523) SPG48 PF14764.6 CRK11777.1 - 2 8.9 5.2 12 6.4 0.2 3.1 3 0 0 3 3 3 0 AP-5 complex subunit, vesicle trafficking PSCyt3 PF07627.11 CRK11777.1 - 7.7 6.9 9.2 13 6.2 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1588) HECT PF00632.25 CRK11779.1 - 8.2e-79 265.3 0.0 9.9e-79 265.0 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Thiolase_N PF00108.23 CRK11780.1 - 1.1e-74 251.1 5.8 1.4e-74 250.7 5.8 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CRK11780.1 - 7.6e-39 132.2 0.2 1.5e-38 131.2 0.2 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.10 CRK11780.1 - 0.013 15.7 0.0 0.043 14.0 0.0 1.9 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal SRPRB PF09439.10 CRK11781.1 - 0.006 16.0 1.1 0.012 15.0 1.1 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Dna2 PF08696.11 CRK11782.1 - 8.8e-72 241.2 0.2 8.8e-72 241.2 0.2 1.7 2 0 0 2 2 2 1 DNA replication factor Dna2 Cas_Cas4 PF01930.17 CRK11782.1 - 8.1e-13 48.8 0.9 2.2e-09 37.6 0.2 2.3 2 0 0 2 2 2 2 Domain of unknown function DUF83 AAA_30 PF13604.6 CRK11782.1 - 5.4e-09 36.1 0.4 9.6e-09 35.2 0.4 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CRK11782.1 - 1.4e-06 28.7 0.5 3.4e-06 27.4 0.5 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CRK11782.1 - 1.8e-06 27.9 0.5 6.9e-06 26.0 0.1 2.0 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 CRK11782.1 - 0.0013 18.4 0.1 0.0024 17.6 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain UvrD-helicase PF00580.21 CRK11782.1 - 0.0029 17.2 0.5 0.0069 15.9 0.5 1.6 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_16 PF13191.6 CRK11782.1 - 0.0049 17.3 0.2 0.017 15.5 0.0 2.0 2 0 0 2 2 1 1 AAA ATPase domain CbiA PF01656.23 CRK11782.1 - 0.014 15.4 0.5 0.037 14.1 0.5 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_7 PF12775.7 CRK11782.1 - 0.016 14.8 0.1 0.034 13.6 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF87 PF01935.17 CRK11782.1 - 0.024 14.8 0.7 0.088 12.9 0.2 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain ResIII PF04851.15 CRK11782.1 - 0.038 14.0 0.1 0.098 12.6 0.1 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit RuvB_N PF05496.12 CRK11782.1 - 0.044 13.5 0.0 0.098 12.4 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain PIF1 PF05970.14 CRK11782.1 - 0.062 12.5 0.1 0.1 11.7 0.1 1.3 1 0 0 1 1 1 0 PIF1-like helicase NTPase_1 PF03266.15 CRK11782.1 - 0.072 13.0 0.2 0.18 11.7 0.2 1.6 1 0 0 1 1 1 0 NTPase Viral_helicase1 PF01443.18 CRK11782.1 - 0.11 12.2 0.2 0.32 10.7 0.1 1.9 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase MeaB PF03308.16 CRK11782.1 - 0.12 11.3 0.0 0.22 10.4 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA PF00004.29 CRK11782.1 - 0.18 12.2 0.3 0.49 10.8 0.3 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 CRK11782.1 - 0.76 10.3 2.2 3.3 8.3 0.1 2.7 3 0 0 3 3 2 0 AAA domain ArAE_2_N PF10337.9 CRK11783.1 - 0.0027 16.8 5.7 2.8 6.9 0.1 3.2 2 1 1 3 3 3 3 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 CRK11783.1 - 0.041 14.0 6.0 0.07 13.3 6.0 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein-like SIR2 PF02146.17 CRK11784.1 - 8.5e-56 188.7 0.0 1.9e-55 187.5 0.0 1.6 1 0 0 1 1 1 1 Sir2 family Pkinase PF00069.25 CRK11784.1 - 1.7e-17 63.7 0.0 6e-17 61.9 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK11784.1 - 1.1e-10 41.2 0.0 1.3e-09 37.8 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase DCB PF16213.5 CRK11784.1 - 0.00012 21.7 0.1 0.023 14.4 0.1 2.4 2 0 0 2 2 2 2 Dimerisation and cyclophilin-binding domain of Mon2 Med16 PF11635.8 CRK11784.1 - 0.046 11.7 0.0 0.24 9.3 0.0 2.0 2 0 0 2 2 2 0 Mediator complex subunit 16 Cation_ATPase_C PF00689.21 CRK11785.1 - 1.2e-40 139.2 10.9 1.2e-40 139.2 10.9 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 CRK11785.1 - 2.6e-21 75.5 0.0 5e-21 74.6 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 CRK11785.1 - 3.6e-19 69.0 0.6 3.6e-19 69.0 0.6 2.7 2 1 1 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 CRK11785.1 - 3.9e-18 66.5 0.7 1.3e-17 64.8 0.7 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CRK11785.1 - 1.3e-05 25.1 0.3 3.1e-05 23.8 0.3 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CRK11785.1 - 0.00014 21.5 0.0 0.00037 20.1 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.7 CRK11785.1 - 0.036 14.5 0.0 0.065 13.6 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase SurE PF01975.17 CRK11786.1 - 9.9e-51 172.3 0.0 1.6e-50 171.6 0.0 1.4 1 0 0 1 1 1 1 Survival protein SurE TTL PF03133.15 CRK11786.1 - 3.4e-10 39.5 0.0 5e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 CRK11786.1 - 0.0042 16.4 0.0 0.0068 15.7 0.0 1.2 1 0 0 1 1 1 1 YheC/D like ATP-grasp DASH_Duo1 PF08651.10 CRK11789.1 - 2.7e-31 107.1 1.4 4.1e-31 106.6 1.4 1.3 1 0 0 1 1 1 1 DASH complex subunit Duo1 DUF1682 PF07946.14 CRK11789.1 - 0.0018 17.6 4.2 0.002 17.4 4.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) CD99L2 PF12301.8 CRK11789.1 - 0.5 10.6 3.7 0.22 11.8 1.2 1.7 2 0 0 2 2 2 0 CD99 antigen like protein 2 Menin PF05053.13 CRK11789.1 - 0.73 8.1 4.8 0.73 8.1 3.9 1.3 1 1 0 1 1 1 0 Menin RNase_H2-Ydr279 PF09468.10 CRK11790.1 - 2.9e-43 147.8 0.9 4.5e-43 147.2 0.0 1.8 2 0 0 2 2 2 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 CRK11790.1 - 7.6e-24 83.8 0.0 1.9e-23 82.5 0.0 1.7 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain SVIP PF15811.5 CRK11790.1 - 0.12 12.9 5.2 0.31 11.5 5.2 1.7 1 0 0 1 1 1 0 Small VCP/p97-interacting protein zf-primase PF09329.11 CRK11791.1 - 4.9e-18 64.7 0.7 9.4e-18 63.8 0.7 1.5 1 0 0 1 1 1 1 Primase zinc finger zf-C3HC4_2 PF13923.6 CRK11798.1 - 0.0013 18.5 9.3 0.0019 18.0 9.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 CRK11798.1 - 0.0018 18.1 1.7 0.0027 17.5 1.7 1.2 1 0 0 1 1 1 1 zf-RING of BARD1-type protein FYVE_2 PF02318.16 CRK11798.1 - 0.0046 17.2 1.1 0.0071 16.6 1.1 1.3 1 0 0 1 1 1 1 FYVE-type zinc finger zf-RING_2 PF13639.6 CRK11798.1 - 0.0069 16.7 6.9 0.011 16.1 6.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-DNL PF05180.12 CRK11798.1 - 0.0084 16.0 0.8 0.016 15.2 0.1 1.8 1 1 1 2 2 2 1 DNL zinc finger U-box PF04564.15 CRK11798.1 - 0.022 14.9 0.0 0.034 14.3 0.0 1.3 1 0 0 1 1 1 0 U-box domain zf-RING_5 PF14634.6 CRK11798.1 - 0.033 14.1 7.0 0.053 13.5 7.0 1.4 1 0 0 1 1 1 0 zinc-RING finger domain DUF1272 PF06906.11 CRK11798.1 - 0.089 12.9 4.9 0.15 12.2 4.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_4 PF14570.6 CRK11798.1 - 0.096 12.5 6.6 0.18 11.6 6.6 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.25 CRK11798.1 - 0.31 11.0 10.6 0.49 10.3 10.6 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CRK11798.1 - 0.41 10.8 8.3 0.87 9.8 8.2 1.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 CRK11798.1 - 0.41 10.5 6.7 0.52 10.2 5.7 1.6 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Cpn10 PF00166.21 CRK11818.1 - 1.1e-14 54.2 0.0 1.2e-14 54.1 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit DUF3419 PF11899.8 CRK11840.1 - 1e-58 199.4 0.0 1.2e-58 199.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) DUF4820 PF16091.5 CRK11840.1 - 0.0089 15.4 0.7 0.011 15.1 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4820) RPN2_C PF18004.1 CRK11840.1 - 0.019 14.9 3.9 0.025 14.5 3.9 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain TRAP_alpha PF03896.16 CRK11840.1 - 0.38 9.9 2.3 0.63 9.2 2.3 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RNA_polI_A34 PF08208.11 CRK11840.1 - 1.6 8.7 15.3 2.3 8.3 15.3 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DNA_pol_phi PF04931.13 CRK11840.1 - 6 4.8 11.0 7.9 4.4 11.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi Bax1-I PF01027.20 CRK11844.1 - 0.00027 20.8 0.5 0.00031 20.6 0.5 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 EPSP_synthase PF00275.20 CRK11847.1 - 1.3e-130 435.8 0.0 2.1e-130 435.1 0.0 1.3 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 CRK11847.1 - 1e-101 339.5 0.0 1.5e-101 339.0 0.0 1.3 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.15 CRK11847.1 - 3.5e-56 191.0 0.0 5.3e-56 190.4 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 CRK11847.1 - 1.2e-36 126.2 0.0 4.4e-35 121.2 0.0 2.4 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 CRK11847.1 - 5.2e-24 84.3 0.0 1.2e-23 83.2 0.0 1.6 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Fe-ADH_2 PF13685.6 CRK11847.1 - 2.3e-07 30.8 0.0 7e-07 29.2 0.0 1.8 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase SDH_C PF18317.1 CRK11847.1 - 0.023 14.5 0.7 0.065 13.0 0.7 1.8 1 0 0 1 1 1 0 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 CRK11847.1 - 0.075 13.1 0.0 0.27 11.3 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase AAA_22 PF13401.6 CRK11847.1 - 0.11 12.7 0.0 0.32 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CRK11847.1 - 0.12 12.8 0.0 0.59 10.5 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain zf-C2H2 PF00096.26 CRK11848.1 - 3.5e-08 33.4 17.8 0.0093 16.4 1.3 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CRK11848.1 - 0.0016 19.2 12.5 1.2 10.1 1.2 4.1 3 0 0 3 3 3 3 C2H2-type zinc finger CENP-T_C PF15511.6 CRK11849.1 - 8e-09 35.6 0.1 9.7e-09 35.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 CRK11849.1 - 3.5e-05 24.2 0.1 4.1e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 CRK11849.1 - 8.6e-05 22.6 0.1 0.00013 22.1 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 CRK11849.1 - 0.00036 20.7 0.1 0.00065 19.9 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 CRK11849.1 - 0.00042 20.7 0.1 0.00056 20.2 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 CRK11849.1 - 0.0087 16.1 0.0 0.01 15.9 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 CRK11849.1 - 0.023 14.7 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 CRK11849.1 - 0.095 12.5 0.1 0.12 12.2 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) HIGH_NTase1_ass PF16581.5 CRK11849.1 - 0.11 12.5 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region Histone PF00125.24 CRK11850.1 - 1.6e-51 174.1 2.5 1.8e-51 173.9 2.5 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 CRK11850.1 - 8.4e-06 26.1 0.0 1.3e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 CRK11850.1 - 3.4e-05 24.5 1.0 3.9e-05 24.3 1.0 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 CRK11850.1 - 3.6e-05 23.8 0.4 6.4e-05 23.0 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 CRK11850.1 - 0.0035 17.6 0.3 0.0065 16.7 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 CRK11850.1 - 0.028 14.5 0.2 0.046 13.8 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 CRK11850.1 - 0.057 13.4 0.0 0.097 12.7 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated RNA_pol_Rpb1_5 PF04998.17 CRK11851.1 - 5e-86 288.4 0.0 8e-86 287.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 CRK11851.1 - 3.1e-68 229.2 0.3 4.5e-67 225.4 0.2 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.12 CRK11851.1 - 1.1e-33 116.9 0.0 2.1e-32 112.7 0.0 2.7 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.18 CRK11851.1 - 6e-30 104.2 0.0 1.4e-29 103.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 CRK11851.1 - 5.1e-16 58.6 0.0 2e-15 56.7 0.0 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 SPX PF03105.19 CRK11851.1 - 3.6 7.4 9.3 0.97 9.3 4.3 2.1 2 0 0 2 2 2 0 SPX domain zf-C2H2 PF00096.26 CRK11852.1 - 9.3e-06 25.8 7.3 0.015 15.7 1.3 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CRK11852.1 - 0.0063 17.3 2.8 6.1 8.0 0.5 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger CENP-T_C PF15511.6 CRK11853.1 - 8e-09 35.6 0.1 9.7e-09 35.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 CRK11853.1 - 3.5e-05 24.2 0.1 4.1e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 CRK11853.1 - 8.6e-05 22.6 0.1 0.00013 22.1 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 CRK11853.1 - 0.00036 20.7 0.1 0.00065 19.9 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 CRK11853.1 - 0.00042 20.7 0.1 0.00056 20.2 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 CRK11853.1 - 0.0087 16.1 0.0 0.01 15.9 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 CRK11853.1 - 0.023 14.7 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 CRK11853.1 - 0.095 12.5 0.1 0.12 12.2 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) HIGH_NTase1_ass PF16581.5 CRK11853.1 - 0.11 12.5 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region Histone PF00125.24 CRK11854.1 - 1.6e-51 174.1 2.5 1.8e-51 173.9 2.5 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 CRK11854.1 - 8.4e-06 26.1 0.0 1.3e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 CRK11854.1 - 3.4e-05 24.5 1.0 3.9e-05 24.3 1.0 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 CRK11854.1 - 3.6e-05 23.8 0.4 6.4e-05 23.0 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 CRK11854.1 - 0.0035 17.6 0.3 0.0065 16.7 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 CRK11854.1 - 0.028 14.5 0.2 0.046 13.8 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 CRK11854.1 - 0.057 13.4 0.0 0.097 12.7 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated DUF1115 PF06544.12 CRK11855.1 - 5e-50 169.4 0.5 1e-49 168.4 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) PRP3 PF08572.10 CRK11855.1 - 6.8e-27 94.7 2.8 1.2e-26 93.8 2.8 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) Paramyxo_NS_C PF02725.14 CRK11855.1 - 0.69 10.0 2.9 1.2 9.2 2.9 1.3 1 0 0 1 1 1 0 Non-structural protein C RNA_pol_Rpb1_5 PF04998.17 CRK11856.1 - 2.3e-85 286.2 0.0 3.7e-85 285.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 CRK11856.1 - 2.2e-67 226.4 0.1 4e-67 225.6 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.12 CRK11856.1 - 1.5e-33 116.5 0.0 1.1e-32 113.6 0.0 2.4 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.18 CRK11856.1 - 5.4e-30 104.4 0.0 1.3e-29 103.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 CRK11856.1 - 5.6e-16 58.4 0.0 1.9e-15 56.7 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Nop14 PF04147.12 CRK11856.1 - 0.61 8.2 7.7 1.3 7.2 7.7 1.4 1 0 0 1 1 1 0 Nop14-like family zf-C2H2 PF00096.26 CRK11857.1 - 2.6e-13 49.6 20.7 6.8e-05 23.1 0.7 3.8 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CRK11857.1 - 4.6e-11 42.6 16.4 0.0014 19.3 0.7 4.2 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CRK11857.1 - 0.0011 19.2 18.5 0.0016 18.8 2.8 3.8 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 CRK11857.1 - 0.058 13.4 10.8 0.075 13.0 0.3 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 CRK11857.1 - 0.22 11.3 14.7 0.057 13.2 2.5 3.6 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2HC_2 PF13913.6 CRK11857.1 - 0.25 11.3 2.3 0.45 10.5 0.5 2.4 1 1 1 2 2 2 0 zinc-finger of a C2HC-type zf-BED PF02892.15 CRK11857.1 - 0.55 10.3 10.1 2 8.5 6.4 2.5 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_2 PF12756.7 CRK11857.1 - 1.6 9.1 7.5 11 6.4 5.9 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_8 PF15909.5 CRK11857.1 - 1.7 9.0 10.0 2 8.8 5.9 2.8 2 1 1 3 3 3 0 C2H2-type zinc ribbon zf-C2H2 PF00096.26 CRK11858.1 - 2.7e-13 49.5 20.7 6.8e-05 23.1 0.7 3.8 4 0 0 4 4 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CRK11858.1 - 4.7e-11 42.5 16.4 0.0014 19.3 0.7 4.2 4 0 0 4 4 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CRK11858.1 - 0.0012 19.2 18.5 0.0016 18.8 2.8 3.8 4 0 0 4 4 4 2 Zinc-finger double domain DUF5012 PF16404.5 CRK11858.1 - 0.057 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5012) zf-C2H2_6 PF13912.6 CRK11858.1 - 0.058 13.4 10.8 0.076 13.0 0.3 3.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 CRK11858.1 - 0.24 11.2 14.7 0.058 13.2 2.5 3.6 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2HC_2 PF13913.6 CRK11858.1 - 0.26 11.2 2.3 0.46 10.4 0.5 2.4 1 1 1 2 2 2 0 zinc-finger of a C2HC-type zf-BED PF02892.15 CRK11858.1 - 0.55 10.3 10.1 2.1 8.5 6.4 2.6 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_2 PF12756.7 CRK11858.1 - 1.5 9.2 7.4 11 6.5 5.8 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_8 PF15909.5 CRK11858.1 - 1.7 9.0 9.8 2.1 8.7 6.0 2.8 2 1 1 3 3 3 0 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 CRK11858.1 - 2.2 8.7 12.8 3.9 7.9 0.2 3.8 3 1 1 4 4 3 0 Zinc-finger double-stranded RNA-binding DEAD_2 PF06733.15 CRK11859.1 - 1.5e-56 190.8 0.6 2.8e-56 189.9 0.6 1.5 1 0 0 1 1 1 1 DEAD_2 HBB PF06777.11 CRK11859.1 - 7.9e-48 162.7 1.0 3.5e-43 147.5 0.2 2.5 2 0 0 2 2 2 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 CRK11859.1 - 4.3e-42 144.2 0.0 9.1e-42 143.1 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain DDHD PF02862.17 CRK11859.1 - 2.3e-21 77.0 0.0 3.2e-19 70.0 0.0 3.0 2 1 0 2 2 2 1 DDHD domain ResIII PF04851.15 CRK11859.1 - 0.00027 21.0 0.0 0.0031 17.5 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DSPc PF00782.20 CRK11859.1 - 0.001 18.9 0.0 0.0081 16.0 0.0 2.3 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain DEAD PF00270.29 CRK11859.1 - 0.0047 16.7 0.0 0.25 11.1 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase SNF2_N PF00176.23 CRK11859.1 - 0.021 13.6 0.0 0.17 10.6 0.0 2.2 1 1 0 1 1 1 0 SNF2 family N-terminal domain Abhydrolase_1 PF00561.20 CRK11859.1 - 0.083 12.5 0.0 0.23 11.1 0.0 1.7 1 0 0 1 1 1 0 alpha/beta hydrolase fold ANAPC4_WD40 PF12894.7 CRK11860.1 - 0.00037 20.7 0.0 0.12 12.7 0.0 3.7 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CRK11860.1 - 0.002 18.9 1.1 1.3 10.0 0.0 4.0 4 1 0 4 4 4 1 WD domain, G-beta repeat CNH PF00780.22 CRK11860.1 - 0.021 14.4 0.1 2.6 7.6 0.0 2.8 2 1 1 3 3 3 0 CNH domain LCM PF04072.14 CRK11861.1 - 1.9e-20 73.6 0.0 1.2e-19 71.0 0.0 1.9 2 0 0 2 2 2 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.6 CRK11861.1 - 2.2e-05 24.3 10.0 2.4e-05 24.3 0.0 4.6 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_3 PF13415.6 CRK11861.1 - 4.1 7.8 7.9 6.1 7.3 0.0 4.2 6 0 0 6 6 6 0 Galactose oxidase, central domain RGS12_us1 PF16613.5 CRK11862.1 - 0.0031 17.8 0.1 0.0093 16.3 0.1 1.8 1 0 0 1 1 1 1 Unstructured region of RGS12 Phe_hydrox_dim PF07976.12 CRK11863.1 - 1.4e-39 135.8 0.0 2.9e-39 134.8 0.0 1.6 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Peptidase_C48 PF02902.19 CRK11863.1 - 2.5e-15 56.9 0.0 4.5e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Host_attach PF10116.9 CRK11863.1 - 0.042 14.4 2.6 1.6 9.3 0.0 2.9 2 0 0 2 2 2 0 Protein required for attachment to host cells RGS PF00615.19 CRK11864.1 - 9.7e-10 38.8 0.0 1.4e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain NMT PF01233.19 CRK11865.1 - 0.022 14.6 0.5 2.9 7.7 0.0 2.2 2 0 0 2 2 2 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain DUF3999 PF13163.6 CRK11865.1 - 0.036 13.3 0.0 8.5 5.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3999) DUF5132 PF17195.4 CRK11865.1 - 0.37 10.9 2.7 27 5.0 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF5132) RGS PF00615.19 CRK11866.1 - 2.8e-09 37.3 0.0 4.1e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain MHYT PF03707.16 CRK11867.1 - 3.8e-19 68.6 18.1 2.2e-10 40.5 0.9 5.3 6 0 0 6 6 6 3 Bacterial signalling protein N terminal repeat NMT PF01233.19 CRK11867.1 - 0.012 15.5 0.2 6.1 6.7 0.0 2.3 2 0 0 2 2 2 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain CitX PF03802.14 CRK11867.1 - 0.034 13.9 0.0 11 5.8 0.0 2.3 2 0 0 2 2 2 0 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase PDR_CDR PF06422.12 CRK11867.1 - 0.14 12.1 1.1 0.32 10.9 1.1 1.5 1 0 0 1 1 1 0 CDR ABC transporter CCB1 PF12046.8 CRK11867.1 - 1.1 8.5 3.4 6.9 6.0 0.0 2.9 2 1 1 3 3 3 0 Cofactor assembly of complex C subunit B DUF4131 PF13567.6 CRK11867.1 - 5 6.8 12.8 0.077 12.7 1.6 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) AAA PF00004.29 CRK11869.1 - 4.2e-38 130.8 0.0 4e-37 127.6 0.0 2.5 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CRK11869.1 - 7.2e-07 28.9 0.3 1.9e-06 27.6 0.3 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 CRK11869.1 - 2.2e-06 28.1 1.9 0.0016 18.9 0.0 3.8 3 1 1 4 4 4 1 AAA ATPase domain WD40 PF00400.32 CRK11869.1 - 6.4e-06 26.8 9.1 0.0092 16.8 0.2 4.1 3 1 0 3 3 3 2 WD domain, G-beta repeat RuvB_N PF05496.12 CRK11869.1 - 2.9e-05 23.9 0.0 7e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CRK11869.1 - 4.2e-05 23.8 0.7 0.11 12.8 0.1 3.9 3 1 1 4 4 4 1 AAA domain AAA_33 PF13671.6 CRK11869.1 - 0.00028 21.0 0.2 0.013 15.7 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CRK11869.1 - 0.002 18.6 0.8 0.12 12.9 0.0 3.0 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 CRK11869.1 - 0.0027 17.5 0.0 0.0054 16.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 CRK11869.1 - 0.0062 16.6 0.0 0.017 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CRK11869.1 - 0.023 14.7 0.1 0.06 13.4 0.1 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 CRK11869.1 - 0.028 14.8 0.0 0.092 13.1 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 CRK11869.1 - 0.057 13.1 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 CRK11869.1 - 0.067 12.6 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 CRK11869.1 - 0.078 12.2 0.3 0.16 11.1 0.0 1.6 2 0 0 2 2 2 0 TIP49 P-loop domain TniB PF05621.11 CRK11869.1 - 0.13 11.7 0.0 1.2 8.5 0.0 2.4 1 1 1 2 2 2 0 Bacterial TniB protein PH_TFIIH PF08567.11 CRK11870.1 - 5.6e-26 90.7 0.0 1.2e-25 89.7 0.0 1.5 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain E1_dh PF00676.20 CRK11871.1 - 5e-31 107.8 0.0 7e-31 107.3 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component 2-oxogl_dehyd_N PF16078.5 CRK11871.1 - 4.1e-20 71.1 1.1 7e-20 70.3 1.1 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus BioY PF02632.14 CRK11871.1 - 0.088 12.9 0.2 0.15 12.1 0.2 1.2 1 0 0 1 1 1 0 BioY family Mus7 PF09462.10 CRK11872.1 - 1.7e-73 248.5 0.3 1.7e-73 248.5 0.3 1.5 2 0 0 2 2 2 1 Mus7/MMS22 family MHYT PF03707.16 CRK11873.1 - 1.3e-20 73.3 21.3 4.8e-11 42.7 0.8 5.0 5 1 0 5 5 5 3 Bacterial signalling protein N terminal repeat DUF4131 PF13567.6 CRK11873.1 - 0.0043 16.7 1.8 0.0043 16.7 1.8 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4131) CCB1 PF12046.8 CRK11873.1 - 0.012 15.0 3.1 1.8 7.9 0.1 3.3 2 2 1 3 3 3 0 Cofactor assembly of complex C subunit B PDR_CDR PF06422.12 CRK11873.1 - 0.018 14.9 0.7 0.052 13.5 0.7 1.8 1 0 0 1 1 1 0 CDR ABC transporter DUF3875 PF12991.7 CRK11873.1 - 0.13 12.2 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3875) YfhO PF09586.10 CRK11873.1 - 1.1 7.4 4.2 1.6 6.9 4.2 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Virul_fac_BrkB PF03631.15 CRK11873.1 - 5.2 6.6 20.4 2.2 7.8 14.1 2.4 1 1 1 2 2 2 0 Virulence factor BrkB WD40 PF00400.32 CRK11874.1 - 4.1e-17 62.2 15.9 1.4e-05 25.8 0.0 6.4 6 1 0 6 6 6 5 WD domain, G-beta repeat AAA_lid_3 PF17862.1 CRK11874.1 - 6.2e-07 29.1 0.6 1.8e-06 27.6 0.3 2.0 2 0 0 2 2 2 1 AAA+ lid domain AAA PF00004.29 CRK11874.1 - 0.024 15.0 0.0 0.19 12.2 0.0 2.5 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) BSD PF03909.17 CRK11875.1 - 5.7e-27 93.5 4.8 1.5e-12 47.3 0.1 3.4 3 0 0 3 3 3 2 BSD domain PH_TFIIH PF08567.11 CRK11875.1 - 3.7e-25 88.1 0.0 8.1e-25 87.0 0.0 1.6 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain DUF4150 PF13665.6 CRK11875.1 - 0.038 14.2 0.1 2.2 8.4 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4150) Glyco_hydro_11 PF00457.17 CRK11875.1 - 0.075 12.7 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 11 PRO8NT PF08082.11 CRK11875.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 PRO8NT (NUC069), PrP8 N-terminal domain E1_dh PF00676.20 CRK11876.1 - 2e-58 197.7 0.0 2.8e-58 197.2 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 CRK11876.1 - 1.6e-56 190.2 0.2 2.6e-56 189.5 0.2 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal Transket_pyr PF02779.24 CRK11876.1 - 8.4e-27 94.0 0.0 6.2e-20 71.6 0.0 2.7 1 1 1 2 2 2 2 Transketolase, pyrimidine binding domain 2-oxogl_dehyd_N PF16078.5 CRK11876.1 - 7.3e-20 70.3 1.1 1.6e-19 69.2 1.1 1.6 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus YceG_bac PF14266.6 CRK11876.1 - 0.13 11.2 0.1 0.21 10.5 0.1 1.2 1 0 0 1 1 1 0 Putative component of 'biosynthetic module' BioY PF02632.14 CRK11876.1 - 0.2 11.7 0.2 0.35 10.9 0.2 1.3 1 0 0 1 1 1 0 BioY family DUF5089 PF17002.5 CRK11877.1 - 0.07 13.0 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5089) OAD_gamma PF04277.13 CRK11877.1 - 0.16 12.6 0.1 0.45 11.1 0.1 1.8 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Mus7 PF09462.10 CRK11878.1 - 1.5e-12 47.2 0.7 2.4e-12 46.5 0.7 1.3 1 0 0 1 1 1 1 Mus7/MMS22 family TrbI_Ftype PF09677.10 CRK11878.1 - 0.036 14.4 0.8 0.81 10.0 0.1 3.0 3 0 0 3 3 3 0 Type-F conjugative transfer system protein (TrbI_Ftype) Mus7 PF09462.10 CRK11879.1 - 2.1e-109 367.1 3.1 3e-109 366.6 3.1 1.2 1 0 0 1 1 1 1 Mus7/MMS22 family AAA_2 PF07724.14 CRK11880.1 - 1.3e-50 171.8 0.2 7.9e-25 87.9 0.0 3.1 4 0 0 4 4 4 2 AAA domain (Cdc48 subfamily) AAA PF00004.29 CRK11880.1 - 8.3e-17 61.9 0.0 2.2e-11 44.3 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 CRK11880.1 - 6.8e-08 32.5 0.0 1.5e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 CRK11880.1 - 7.5e-08 32.5 0.0 1.5e-06 28.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) MCM PF00493.23 CRK11880.1 - 3.2e-07 29.7 0.1 0.0002 20.5 0.0 2.3 2 0 0 2 2 2 2 MCM P-loop domain AAA_22 PF13401.6 CRK11880.1 - 3.1e-05 24.3 0.2 0.0024 18.1 0.1 3.2 2 1 0 2 2 2 1 AAA domain Kri1 PF05178.12 CRK11880.1 - 3.5e-05 24.3 3.5 0.18 12.4 0.2 2.4 2 0 0 2 2 2 2 KRI1-like family Torsin PF06309.11 CRK11880.1 - 5.5e-05 23.3 0.0 4.5 7.4 0.0 3.3 3 0 0 3 3 3 2 Torsin HD_5 PF13487.6 CRK11880.1 - 0.00056 20.1 0.4 3 8.2 0.0 3.3 4 0 0 4 4 4 2 HD domain Sigma54_activat PF00158.26 CRK11880.1 - 0.002 17.9 0.1 0.081 12.6 0.1 2.9 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_16 PF13191.6 CRK11880.1 - 0.0035 17.7 0.4 0.039 14.3 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 CRK11880.1 - 0.0054 16.3 0.0 0.0089 15.6 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region NACHT PF05729.12 CRK11880.1 - 0.017 15.0 0.6 3.5 7.5 0.2 3.2 2 1 0 2 2 2 0 NACHT domain DUF1589 PF07628.11 CRK11880.1 - 0.025 14.7 2.3 2.4 8.3 0.3 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1589) T2SSE PF00437.20 CRK11880.1 - 0.053 12.6 0.1 0.091 11.8 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_14 PF13173.6 CRK11880.1 - 0.066 13.2 0.0 0.2 11.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 CRK11880.1 - 0.067 13.2 0.0 2.2 8.3 0.0 2.9 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit DEAD PF00270.29 CRK11880.1 - 0.086 12.6 0.1 32 4.2 0.0 3.3 3 0 0 3 3 3 0 DEAD/DEAH box helicase AAA_19 PF13245.6 CRK11880.1 - 0.09 13.1 0.0 0.32 11.3 0.0 2.0 2 0 0 2 2 1 0 AAA domain FtsK_SpoIIIE PF01580.18 CRK11880.1 - 0.096 12.0 0.0 0.3 10.4 0.0 1.8 1 0 0 1 1 1 0 FtsK/SpoIIIE family Mg_chelatase PF01078.21 CRK11880.1 - 0.12 11.7 0.0 12 5.2 0.0 3.0 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI PIF1 PF05970.14 CRK11880.1 - 0.13 11.4 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase AAA_lid_5 PF17865.1 CRK11880.1 - 0.16 12.1 1.0 22 5.2 0.1 2.4 2 0 0 2 2 2 0 Midasin AAA lid domain AAA_18 PF13238.6 CRK11880.1 - 0.19 12.3 0.0 0.19 12.3 0.0 3.3 3 0 0 3 3 3 0 AAA domain COX14 PF14880.6 CRK11880.1 - 0.21 11.4 1.4 20 5.1 0.1 2.3 2 0 0 2 2 2 0 Cytochrome oxidase c assembly PgaD PF13994.6 CRK11880.1 - 0.41 10.7 2.6 20 5.2 0.2 2.2 2 0 0 2 2 2 0 PgaD-like protein Alpha-amylase_C PF02806.18 CRK11881.1 - 2.6e-27 95.1 0.0 6.9e-27 93.8 0.0 1.8 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 CRK11881.1 - 7.7e-19 67.8 0.0 2.3e-18 66.3 0.0 1.9 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 CRK11881.1 - 8.3e-14 51.9 0.5 2.1e-10 40.7 0.1 2.3 1 1 1 2 2 2 2 Alpha amylase, catalytic domain AMPK1_CBM PF16561.5 CRK11881.1 - 0.017 15.3 0.0 0.041 14.1 0.0 1.6 1 0 0 1 1 1 0 Glycogen recognition site of AMP-activated protein kinase COX4 PF02936.14 CRK11882.1 - 5.5e-49 165.7 0.0 6.5e-49 165.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV ATP-synt_ab PF00006.25 CRK11884.1 - 9.8e-62 208.4 0.0 1.5e-61 207.7 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 CRK11884.1 - 2.4e-23 82.5 0.2 6.4e-23 81.0 0.1 1.8 2 0 0 2 2 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA PF00004.29 CRK11884.1 - 0.012 16.0 0.0 0.62 10.5 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 CRK11884.1 - 0.023 13.9 0.5 0.091 11.9 0.1 1.9 2 0 0 2 2 2 0 NB-ARC domain RsgA_GTPase PF03193.16 CRK11884.1 - 0.023 14.6 0.8 0.036 14.0 0.2 1.6 2 0 0 2 2 2 0 RsgA GTPase ATPase_2 PF01637.18 CRK11884.1 - 0.032 14.2 0.0 0.09 12.7 0.0 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea ATPase PF06745.13 CRK11884.1 - 0.044 13.1 0.1 0.073 12.4 0.1 1.4 1 0 0 1 1 1 0 KaiC T3SS_ATPase_C PF18269.1 CRK11884.1 - 0.048 13.5 0.9 0.24 11.3 0.9 2.0 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain NACHT PF05729.12 CRK11884.1 - 0.056 13.4 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_19 PF13245.6 CRK11884.1 - 0.069 13.5 0.8 0.53 10.6 0.2 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CRK11884.1 - 0.09 13.2 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 CRK11884.1 - 0.14 12.5 0.1 0.46 10.9 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain Zn_clus PF00172.18 CRK11885.1 - 3.8e-08 33.3 8.9 6.5e-08 32.6 8.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 CRK11885.1 - 0.013 14.4 0.0 0.021 13.6 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain ORC5_C PF14630.6 CRK11886.1 - 3e-81 273.1 0.0 5.4e-81 272.2 0.0 1.4 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 CRK11886.1 - 3.2e-18 66.7 0.0 7e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.13 CRK11886.1 - 0.023 13.9 0.0 0.039 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) CPT PF07931.12 CRK11886.1 - 0.032 14.1 0.0 0.061 13.2 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein FSA_C PF10479.9 CRK11886.1 - 1.1 7.4 4.0 1.5 6.9 4.0 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus TPT PF03151.16 CRK11887.1 - 1e-53 182.6 9.8 1.3e-53 182.2 9.8 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CRK11887.1 - 1.5e-10 41.4 31.2 4.1e-05 23.8 12.5 3.2 2 2 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 CRK11887.1 - 3.4e-05 23.2 13.2 0.00018 20.8 13.2 2.0 1 1 0 1 1 1 1 UAA transporter family PUNUT PF16913.5 CRK11887.1 - 6.6 5.9 15.8 2.5 7.2 9.4 2.4 1 1 0 2 2 2 0 Purine nucleobase transmembrane transport DUF382 PF04037.13 CRK11889.1 - 2.8e-29 101.8 0.1 2.8e-29 101.8 0.1 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF382) VEFS-Box PF09733.9 CRK11890.1 - 6.2e-10 39.0 0.4 1.1e-09 38.2 0.4 1.3 1 0 0 1 1 1 1 VEFS-Box of polycomb protein PHD PF00628.29 CRK11890.1 - 0.00087 19.1 10.0 0.0024 17.7 4.9 2.7 2 0 0 2 2 2 1 PHD-finger zf_Hakai PF18408.1 CRK11890.1 - 0.077 12.7 0.4 0.24 11.1 0.4 1.9 1 0 0 1 1 1 0 C2H2 Hakai zinc finger domain C1_2 PF03107.16 CRK11890.1 - 0.39 11.1 2.7 5 7.5 0.1 3.1 3 0 0 3 3 3 0 C1 domain LRR_4 PF12799.7 CRK11891.1 - 0.15 12.6 6.1 1.3 9.5 0.2 3.7 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) Shugoshin_C PF07557.11 CRK11893.1 - 6.9e-12 44.9 4.4 3.1e-11 42.9 4.4 2.3 1 0 0 1 1 1 1 Shugoshin C terminus Shugoshin_N PF07558.11 CRK11893.1 - 1.1e-07 31.6 2.8 1.1e-07 31.6 2.8 1.8 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region Metallophos_2 PF12850.7 CRK11894.1 - 2.7e-11 43.9 0.0 3.7e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 CRK11894.1 - 0.027 15.0 0.0 0.55 10.7 0.0 2.1 1 1 1 2 2 2 0 Calcineurin-like phosphoesterase Xpo1 PF08389.12 CRK11895.1 - 9.3e-40 136.1 4.3 3.4e-39 134.3 4.3 2.0 1 0 0 1 1 1 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 CRK11895.1 - 1.4e-33 114.3 2.8 4.8e-33 112.6 2.8 2.0 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 CRK11895.1 - 2.8e-27 94.6 2.8 2.9e-27 94.5 0.8 2.2 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 Alpha-amylase_C PF02806.18 CRK11895.1 - 1e-26 93.2 0.0 2.7e-26 91.9 0.0 1.8 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Aminotran_5 PF00266.19 CRK11895.1 - 2.5e-26 92.5 0.0 4.1e-26 91.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V CRM1_repeat PF18777.1 CRK11895.1 - 4.8e-19 67.6 1.8 9.5e-19 66.6 1.8 1.5 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 CRK11895.1 - 3.9e-12 45.9 0.2 9e-12 44.7 0.2 1.7 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF3385 PF11865.8 CRK11895.1 - 0.052 13.5 0.6 0.53 10.2 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) COX4 PF02936.14 CRK11896.1 - 4.8e-28 97.9 0.0 7e-28 97.4 0.0 1.2 1 1 0 1 1 1 1 Cytochrome c oxidase subunit IV ATP-synt_ab PF00006.25 CRK11898.1 - 9.8e-62 208.4 0.0 1.5e-61 207.7 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 CRK11898.1 - 2.4e-23 82.5 0.2 6.4e-23 81.0 0.1 1.8 2 0 0 2 2 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA PF00004.29 CRK11898.1 - 0.012 16.0 0.0 0.62 10.5 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 CRK11898.1 - 0.023 13.9 0.5 0.091 11.9 0.1 1.9 2 0 0 2 2 2 0 NB-ARC domain RsgA_GTPase PF03193.16 CRK11898.1 - 0.023 14.6 0.8 0.036 14.0 0.2 1.6 2 0 0 2 2 2 0 RsgA GTPase ATPase_2 PF01637.18 CRK11898.1 - 0.032 14.2 0.0 0.09 12.7 0.0 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea ATPase PF06745.13 CRK11898.1 - 0.044 13.1 0.1 0.073 12.4 0.1 1.4 1 0 0 1 1 1 0 KaiC T3SS_ATPase_C PF18269.1 CRK11898.1 - 0.048 13.5 0.9 0.24 11.3 0.9 2.0 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain NACHT PF05729.12 CRK11898.1 - 0.056 13.4 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_19 PF13245.6 CRK11898.1 - 0.069 13.5 0.8 0.53 10.6 0.2 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CRK11898.1 - 0.09 13.2 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 CRK11898.1 - 0.14 12.5 0.1 0.46 10.9 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain Zn_clus PF00172.18 CRK11900.1 - 6.8e-08 32.5 8.6 1.2e-07 31.7 8.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 CRK11900.1 - 0.018 13.9 0.0 0.03 13.2 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain ORC5_C PF14630.6 CRK11901.1 - 3.2e-81 273.0 0.0 4.8e-81 272.4 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 CRK11901.1 - 8.2e-18 65.4 0.0 1.6e-17 64.4 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.13 CRK11901.1 - 0.0093 15.2 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA PF00004.29 CRK11901.1 - 0.094 13.1 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TPT PF03151.16 CRK11902.1 - 4.2e-53 180.6 10.8 5.2e-53 180.3 10.8 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CRK11902.1 - 2.9e-09 37.2 33.0 0.00042 20.5 10.1 3.5 2 2 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 CRK11902.1 - 0.0001 21.7 14.2 0.00079 18.7 14.2 2.1 1 1 0 1 1 1 1 UAA transporter family DUF382 PF04037.13 CRK11903.1 - 3.3e-58 195.4 0.9 3.3e-58 195.4 0.9 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF382) PSP PF04046.16 CRK11903.1 - 2.1e-35 120.3 14.2 2e-17 62.8 3.4 2.6 2 0 0 2 2 2 2 PSP Med8 PF10232.9 CRK11903.1 - 0.00028 20.5 5.4 0.081 12.5 0.5 2.6 2 0 0 2 2 2 2 Mediator of RNA polymerase II transcription complex subunit 8 SUIM_assoc PF16619.5 CRK11903.1 - 0.068 13.2 0.1 0.068 13.2 0.1 5.0 5 0 0 5 5 5 0 Unstructured region C-term to UIM in Ataxin3 VEFS-Box PF09733.9 CRK11904.1 - 2.3e-08 34.0 0.4 3.9e-08 33.2 0.4 1.3 1 0 0 1 1 1 1 VEFS-Box of polycomb protein PHD PF00628.29 CRK11904.1 - 0.0012 18.7 10.5 0.0032 17.3 5.4 2.7 2 0 0 2 2 2 1 PHD-finger zf_Hakai PF18408.1 CRK11904.1 - 0.077 12.7 0.4 0.24 11.1 0.4 1.9 1 0 0 1 1 1 0 C2H2 Hakai zinc finger domain C1_2 PF03107.16 CRK11904.1 - 0.33 11.3 3.2 3.1 8.2 0.2 3.1 3 0 0 3 3 3 0 C1 domain LRR_4 PF12799.7 CRK11905.1 - 0.1 13.1 6.0 1.3 9.5 0.2 3.7 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) ORC6 PF05460.13 CRK11905.1 - 7.7 5.7 17.9 0.61 9.3 5.0 2.4 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) Shugoshin_C PF07557.11 CRK11907.1 - 6.9e-12 44.9 4.4 3.1e-11 42.9 4.4 2.3 1 0 0 1 1 1 1 Shugoshin C terminus Shugoshin_N PF07558.11 CRK11907.1 - 4.1e-08 33.0 2.8 1.1e-07 31.6 2.8 1.8 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Metallophos_2 PF12850.7 CRK11908.1 - 4.8e-08 33.4 0.0 1.1e-07 32.2 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Aminotran_5 PF00266.19 CRK11909.1 - 1.8e-28 99.6 0.0 2.4e-28 99.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 CRK11909.1 - 4.6e-05 22.7 0.0 0.00013 21.3 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class I and II CRM1_C PF08767.11 CRK11910.1 - 6.1e-135 449.5 2.0 6.1e-135 449.5 2.0 3.2 3 1 1 4 4 4 1 CRM1 C terminal Xpo1 PF08389.12 CRK11910.1 - 4.1e-41 140.5 16.5 1.1e-40 139.1 7.5 4.5 3 1 1 4 4 4 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 CRK11910.1 - 1.2e-33 114.5 2.8 3.9e-33 112.9 2.8 2.0 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 CRK11910.1 - 2.3e-27 94.8 0.8 2.3e-27 94.8 0.8 3.1 3 0 0 3 3 3 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 CRK11910.1 - 3e-19 68.2 1.8 7.7e-19 66.9 1.8 1.8 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 CRK11910.1 - 2.3e-12 46.7 0.2 7.2e-12 45.1 0.2 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain Hemocyanin_M PF00372.19 CRK11910.1 - 0.0082 15.4 0.2 0.042 13.0 0.0 2.2 2 1 1 3 3 3 1 Hemocyanin, copper containing domain Vac14_Fab1_bd PF12755.7 CRK11910.1 - 0.085 13.5 3.6 4.9 7.8 0.0 4.9 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region HD_assoc PF13286.6 CRK11910.1 - 0.15 12.6 0.2 27 5.4 0.2 3.6 3 0 0 3 3 3 0 Phosphohydrolase-associated domain DUF3385 PF11865.8 CRK11910.1 - 0.38 10.6 0.0 0.38 10.6 0.0 5.0 7 0 0 7 7 7 0 Domain of unknown function (DUF3385) CRM1_C PF08767.11 CRK11911.1 - 1.1e-17 64.2 0.0 1.4e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 CRM1 C terminal DUF2458 PF10454.9 CRK11913.1 - 0.14 11.8 0.1 0.19 11.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) Ecl1 PF12855.7 CRK11914.1 - 4.1e-14 54.1 16.2 5.4e-14 53.7 16.2 1.2 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins zf-MYND PF01753.18 CRK11914.1 - 0.064 13.4 1.9 0.12 12.4 1.9 1.4 1 0 0 1 1 1 0 MYND finger Ecl1 PF12855.7 CRK11916.1 - 8.6e-14 53.1 14.0 1.3e-13 52.5 14.0 1.3 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins zf-MYND PF01753.18 CRK11916.1 - 0.065 13.3 1.9 0.12 12.4 1.9 1.4 1 0 0 1 1 1 0 MYND finger Cpn60_TCP1 PF00118.24 CRK11919.1 - 1.9e-172 574.3 0.4 2.3e-172 574.1 0.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family His_Phos_1 PF00300.22 CRK11920.1 - 5.8e-22 78.3 0.1 1.9e-21 76.6 0.0 1.9 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.22 CRK11920.1 - 0.02 14.3 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) Podoplanin PF05808.11 CRK11921.1 - 0.021 14.9 0.2 0.037 14.1 0.2 1.4 1 0 0 1 1 1 0 Podoplanin EphA2_TM PF14575.6 CRK11921.1 - 0.041 14.7 0.0 0.077 13.9 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Yip1 PF04893.17 CRK11921.1 - 0.048 13.4 0.0 0.072 12.8 0.0 1.2 1 0 0 1 1 1 0 Yip1 domain CcmD PF04995.14 CRK11921.1 - 0.053 13.6 2.0 0.053 13.6 2.0 1.7 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) SKG6 PF08693.10 CRK11921.1 - 7.7 6.0 8.8 0.13 11.7 1.8 1.7 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Sugar_tr PF00083.24 CRK11922.1 - 2.7e-141 471.5 39.8 8.5e-73 245.7 15.0 3.0 1 1 2 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.16 CRK11922.1 - 5.2e-30 104.6 60.4 9e-15 54.4 22.9 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily CrgA PF06781.12 CRK11922.1 - 0.00018 21.5 0.0 2.1 8.5 0.0 3.7 2 0 0 2 2 2 2 Cell division protein CrgA PsaL PF02605.15 CRK11922.1 - 0.02 14.6 3.3 4.3 7.0 0.0 3.3 4 0 0 4 4 4 0 Photosystem I reaction centre subunit XI BAP PF06639.11 CRK11922.1 - 0.13 12.6 0.0 35 4.8 0.0 2.5 2 0 0 2 2 2 0 Basal layer antifungal peptide (BAP) EMP70 PF02990.16 CRK11922.1 - 0.29 9.8 9.8 2.1 6.9 1.3 2.7 2 0 0 2 2 2 0 Endomembrane protein 70 MFS_1 PF07690.16 CRK11923.1 - 1.4e-20 73.6 40.7 1e-17 64.1 21.3 3.0 1 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK11923.1 - 0.00068 18.6 4.2 0.003 16.5 1.3 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter NUDIX_4 PF14815.6 CRK11924.1 - 5.7e-23 81.0 0.0 1.2e-22 80.0 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain HhH-GPD PF00730.25 CRK11924.1 - 7.9e-18 64.9 0.0 1.7e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein PBP PF01161.20 CRK11924.1 - 3.6e-16 59.7 0.0 6.6e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein HHH PF00633.23 CRK11924.1 - 4.6e-05 23.1 0.1 0.00014 21.5 0.1 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif Synaptobrevin PF00957.21 CRK11924.1 - 0.0082 15.9 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Synaptobrevin DUF3408 PF11888.8 CRK11924.1 - 1.1 9.4 3.4 2.7 8.1 3.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) TMEM154 PF15102.6 CRK11925.1 - 0.026 14.4 1.7 0.046 13.6 0.2 2.1 1 1 1 2 2 2 0 TMEM154 protein family ETF_alpha PF00766.19 CRK11925.1 - 0.034 14.2 0.3 0.061 13.4 0.3 1.4 1 0 0 1 1 1 0 Electron transfer flavoprotein FAD-binding domain Herpes_gE PF02480.16 CRK11925.1 - 0.041 12.6 0.0 0.064 12.0 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Apt1 PF10351.9 CRK11925.1 - 0.047 12.5 3.7 0.07 12.0 3.7 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 CRK11925.1 - 0.22 10.0 1.8 0.28 9.7 1.8 1.1 1 0 0 1 1 1 0 Macoilin family DUF4718 PF15842.5 CRK11925.1 - 3.6 7.4 8.0 6.3 6.5 8.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) Sugar_tr PF00083.24 CRK11926.1 - 1.5e-63 215.3 7.8 1.7e-63 215.1 7.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK11926.1 - 2.1e-17 63.1 33.2 5.8e-10 38.6 8.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Trep_Strep PF09605.10 CRK11926.1 - 0.83 9.6 11.6 3.2 7.7 8.6 3.1 2 1 1 3 3 3 0 Hypothetical bacterial integral membrane protein (Trep_Strep) DUF2567 PF10821.8 CRK11926.1 - 1.9 8.5 10.1 1 9.4 2.7 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2567) CAS_CSE1 PF03378.15 CRK11927.1 - 3.1e-162 540.1 0.6 6.2e-162 539.1 0.0 1.8 3 0 0 3 3 3 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 CRK11927.1 - 2.3e-153 510.4 7.1 3.5e-153 509.8 7.1 1.3 1 0 0 1 1 1 1 Cse1 V-ATPase_H_N PF03224.14 CRK11927.1 - 0.00099 18.5 5.5 0.012 14.9 0.0 3.7 3 2 1 4 4 4 1 V-ATPase subunit H TPR_10 PF13374.6 CRK11927.1 - 0.14 12.0 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF3384 PF11864.8 CRK11928.1 - 2.3e-143 478.6 0.0 3.6e-143 478.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.15 CRK11928.1 - 1.3e-53 181.3 0.0 2.9e-53 180.2 0.0 1.7 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.16 CRK11928.1 - 4.7e-14 52.3 0.1 1.1e-08 34.6 0.0 3.1 3 0 0 3 3 3 2 Tuberin DUF3361 PF11841.8 CRK11928.1 - 0.00019 21.4 0.1 0.0011 18.9 0.0 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF3361) CBP_BcsO PF17037.5 CRK11928.1 - 1.1 9.4 6.8 19 5.4 0.2 3.4 3 0 0 3 3 3 0 Cellulose biosynthesis protein BcsO Acetyltransf_1 PF00583.25 CRK11929.1 - 9.4e-06 25.9 0.0 2.1e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CRK11929.1 - 0.00024 21.4 0.0 0.00049 20.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CRK11929.1 - 0.00078 19.4 0.0 0.0015 18.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CRK11929.1 - 0.013 15.4 0.0 0.037 14.0 0.0 1.7 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_9 PF13527.7 CRK11929.1 - 0.14 12.2 0.0 0.48 10.5 0.0 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ribosomal_L38e PF01781.18 CRK11930.1 - 4.7e-34 116.3 4.9 5.7e-34 116.0 4.9 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family ABM PF03992.16 CRK11931.1 - 2.7e-08 33.8 1.3 0.00069 19.7 0.1 2.6 2 1 0 2 2 2 2 Antibiotic biosynthesis monooxygenase RGS PF00615.19 CRK11932.1 - 2.9e-06 27.5 0.0 6.9e-06 26.3 0.0 1.6 1 1 0 1 1 1 1 Regulator of G protein signaling domain GHMP_kinases_N PF00288.26 CRK11934.1 - 4e-17 62.2 0.0 8.9e-17 61.1 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 CRK11934.1 - 3.3e-10 40.2 0.1 2.6e-09 37.3 0.0 2.3 2 0 0 2 2 2 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 CRK11934.1 - 0.0019 17.7 0.0 0.0034 16.9 0.0 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature PPTA PF01239.22 CRK11936.1 - 7.5e-31 105.0 16.8 6.1e-06 25.8 0.1 5.5 4 1 1 5 5 5 5 Protein prenyltransferase alpha subunit repeat TPR_7 PF13176.6 CRK11936.1 - 0.0029 17.5 2.9 0.028 14.4 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 CRK11936.1 - 0.026 15.0 0.1 0.76 10.3 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat NTF2 PF02136.20 CRK11938.1 - 5.4e-06 27.0 0.0 0.0025 18.4 0.0 2.2 2 0 0 2 2 2 2 Nuclear transport factor 2 (NTF2) domain SnoaL_2 PF12680.7 CRK11938.1 - 0.0041 17.7 0.2 0.051 14.2 0.0 2.5 2 1 0 2 2 2 1 SnoaL-like domain Adeno_PV PF03910.13 CRK11938.1 - 4.4 5.9 6.9 6.2 5.4 6.9 1.2 1 0 0 1 1 1 0 Adenovirus minor core protein PV tRNA-synt_1g PF09334.11 CRK11940.1 - 4.8e-95 318.6 0.2 4.5e-94 315.4 0.2 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 CRK11940.1 - 1.8e-22 79.3 4.3 1.3e-10 40.2 0.0 3.6 1 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 CRK11940.1 - 3.1e-09 36.6 0.0 0.0018 17.7 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 CRK11940.1 - 0.052 12.4 0.0 0.089 11.7 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (K) Acetyltransf_3 PF13302.7 CRK11942.1 - 2.9e-23 83.1 0.0 4.2e-23 82.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 CRK11942.1 - 6.8e-07 29.1 2.0 0.0074 16.0 0.2 3.2 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CRK11942.1 - 0.0016 18.7 0.1 0.046 13.9 0.1 2.3 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.10 CRK11942.1 - 0.0068 16.4 0.0 0.65 10.0 0.0 2.3 2 0 0 2 2 2 1 FR47-like protein PALP PF00291.25 CRK11944.1 - 5.5e-67 226.2 2.9 9e-67 225.5 2.9 1.3 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Ppx-GppA PF02541.16 CRK11946.1 - 1.9e-41 142.4 0.0 9.2e-41 140.1 0.0 1.9 1 1 0 1 1 1 1 Ppx/GppA phosphatase family GDA1_CD39 PF01150.17 CRK11946.1 - 0.084 11.5 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 GDA1/CD39 (nucleoside phosphatase) family DNA_pol_E_B PF04042.16 CRK11950.1 - 5.9e-48 163.0 0.0 8.1e-48 162.6 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 CRK11950.1 - 8.4e-40 135.9 0.0 1.3e-39 135.2 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain Elong-fact-P_C PF09285.11 CRK11950.1 - 0.29 10.9 1.9 1.8 8.4 0.2 2.6 3 0 0 3 3 3 0 Elongation factor P, C-terminal ABC_tran PF00005.27 CRK11952.1 - 1.9e-15 57.6 0.1 2e-14 54.3 0.1 2.2 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CRK11952.1 - 3.2e-10 40.3 0.8 0.00016 21.6 0.3 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CRK11952.1 - 0.00045 20.8 0.1 0.00066 20.2 0.1 1.2 1 0 0 1 1 1 1 AAA domain DUF3584 PF12128.8 CRK11952.1 - 0.00046 17.9 0.2 0.0006 17.5 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) AAA_29 PF13555.6 CRK11952.1 - 0.00099 18.8 0.1 0.0022 17.7 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 CRK11952.1 - 0.0011 18.5 0.0 0.66 9.4 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 CRK11952.1 - 0.0063 16.3 0.0 0.0085 15.8 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CRK11952.1 - 0.013 15.8 0.1 0.073 13.3 0.0 2.2 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.6 CRK11952.1 - 0.013 15.8 0.7 0.024 14.9 0.7 1.4 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 CRK11952.1 - 0.02 14.3 0.2 0.057 12.9 0.2 1.7 1 1 0 1 1 1 0 ADP-ribosylation factor family AAA_16 PF13191.6 CRK11952.1 - 0.022 15.1 0.2 0.046 14.1 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 CRK11952.1 - 0.026 14.1 0.1 0.058 13.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 CRK11952.1 - 0.03 14.2 0.0 0.047 13.6 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase AAA_13 PF13166.6 CRK11952.1 - 0.035 12.8 0.0 0.046 12.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 CRK11952.1 - 0.048 13.4 0.0 0.073 12.8 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_27 PF13514.6 CRK11952.1 - 0.059 13.0 0.0 0.097 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 CRK11952.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family NACHT PF05729.12 CRK11952.1 - 0.15 12.0 0.2 0.26 11.2 0.2 1.4 1 0 0 1 1 1 0 NACHT domain SRP54 PF00448.22 CRK11952.1 - 0.15 11.7 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_24 PF13479.6 CRK11952.1 - 0.19 11.4 0.4 0.54 9.9 0.1 1.8 2 0 0 2 2 2 0 AAA domain CENP-I PF07778.11 CRK11954.1 - 1.8e-22 79.8 0.0 1.9e-14 53.3 0.0 3.1 2 1 1 3 3 3 3 Mis6 Ish1 PF10281.9 CRK11956.1 - 6.4e-05 23.2 0.0 0.00012 22.3 0.0 1.5 2 0 0 2 2 2 1 Putative stress-responsive nuclear envelope protein DNA_meth_N PF18284.1 CRK11956.1 - 0.14 12.0 0.8 0.32 10.9 0.2 1.8 2 0 0 2 2 2 0 DNA methylase N-terminal domain Peptidase_M48_N PF16491.5 CRK11958.1 - 4.8e-63 212.3 8.0 4.8e-63 212.3 8.0 1.7 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 CRK11958.1 - 5.9e-45 153.5 0.1 9.6e-45 152.8 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 CRK11958.1 - 0.024 13.8 0.1 0.057 12.6 0.1 1.6 1 0 0 1 1 1 0 BlaR1 peptidase M56 Ribosomal_L34 PF00468.17 CRK11960.1 - 7.8e-11 41.8 11.5 1.4e-10 41.0 11.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L34 Peptidase_M16_C PF05193.21 CRK11962.1 - 4.9e-21 75.6 0.0 2e-17 63.8 0.0 2.6 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 CRK11962.1 - 3.4e-07 30.4 0.1 2e-06 27.8 0.0 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) M16C_assoc PF08367.11 CRK11962.1 - 0.0021 17.2 3.3 0.41 9.7 2.2 2.4 2 0 0 2 2 2 2 Peptidase M16C associated Zw10 PF06248.13 CRK11964.1 - 1.9e-07 30.0 1.8 5.2e-06 25.3 1.4 2.6 2 1 0 2 2 2 1 Centromere/kinetochore Zw10 Anticodon_1 PF08264.13 CRK11964.1 - 0.03 14.3 0.1 5.1 7.0 0.0 2.6 2 0 0 2 2 2 0 Anticodon-binding domain of tRNA Dsl1_C PF11989.8 CRK11964.1 - 0.053 13.2 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Retrograde transport protein Dsl1 C terminal DUF5525 PF17663.1 CRK11964.1 - 0.62 8.1 9.1 0.91 7.5 9.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5525) CAP_N PF01213.19 CRK11964.1 - 2.9 7.3 7.2 8.1 5.8 7.2 1.7 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PI-PLC-X PF00388.19 CRK11967.1 - 1.1e-107 355.8 0.0 2.9e-57 192.3 0.0 2.4 2 0 0 2 2 2 2 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 CRK11967.1 - 1.5e-42 144.6 0.1 3.4e-42 143.4 0.1 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain PH_12 PF16457.5 CRK11967.1 - 1.1e-08 35.7 4.1 0.0055 17.2 0.0 4.0 3 2 0 3 3 3 2 Pleckstrin homology domain EF-hand_6 PF13405.6 CRK11967.1 - 1.6e-05 24.4 1.2 0.51 10.4 0.0 4.3 5 0 0 5 5 5 2 EF-hand domain C2 PF00168.30 CRK11967.1 - 1.8e-05 24.9 0.0 4.9e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 C2 domain EF-hand_like PF09279.11 CRK11967.1 - 4.4e-05 23.9 0.0 0.014 15.9 0.0 2.7 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_7 PF13499.6 CRK11967.1 - 0.00021 21.6 0.2 1.7 9.2 0.0 3.1 2 0 0 2 2 2 2 EF-hand domain pair GDPD PF03009.17 CRK11967.1 - 0.00053 19.8 0.0 0.9 9.2 0.0 2.5 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family EF-hand_1 PF00036.32 CRK11967.1 - 0.0013 18.1 0.0 3.7 7.3 0.0 3.2 2 0 0 2 2 2 2 EF hand EF-hand_10 PF14788.6 CRK11967.1 - 0.0016 18.3 0.0 2.4 8.1 0.0 3.0 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 CRK11967.1 - 0.0025 17.6 0.0 6.3 6.7 0.0 3.6 4 0 0 4 4 4 2 EF-hand domain pair Gp49 PF05973.14 CRK11967.1 - 0.0093 16.1 0.4 8.5 6.6 0.0 2.8 2 0 0 2 2 2 2 Phage derived protein Gp49-like (DUF891) LRR_5 PF13306.6 CRK11967.1 - 0.11 12.4 0.0 13 5.7 0.0 2.4 2 0 0 2 2 2 0 BspA type Leucine rich repeat region (6 copies) ABM PF03992.16 CRK11970.1 - 1.9e-08 34.3 5.0 0.00097 19.2 0.2 3.2 2 2 0 2 2 2 2 Antibiotic biosynthesis monooxygenase RGS PF00615.19 CRK11972.1 - 1.3e-06 28.6 0.0 3.1e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 Regulator of G protein signaling domain PPTA PF01239.22 CRK11974.1 - 9.9e-30 101.4 13.8 1.5e-05 24.6 0.1 5.5 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat GHMP_kinases_N PF00288.26 CRK11974.1 - 6.9e-17 61.4 0.0 1.7e-16 60.2 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 CRK11974.1 - 9.2e-10 38.8 0.1 4.9e-09 36.4 0.0 2.2 2 0 0 2 2 2 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 CRK11974.1 - 0.0044 16.6 0.0 0.0086 15.6 0.0 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature TPR_7 PF13176.6 CRK11974.1 - 0.016 15.2 3.1 0.055 13.5 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat NTF2 PF02136.20 CRK11976.1 - 1.3e-11 45.1 0.0 0.0041 17.7 0.0 3.3 3 0 0 3 3 3 3 Nuclear transport factor 2 (NTF2) domain SnoaL_2 PF12680.7 CRK11976.1 - 6.2e-07 30.0 0.1 0.084 13.5 0.0 2.8 2 0 0 2 2 2 2 SnoaL-like domain DUF1590 PF07629.11 CRK11976.1 - 0.00059 19.6 1.3 1.6 8.6 0.1 2.9 2 0 0 2 2 2 2 Protein of unknown function (DUF1590) DUF624 PF04854.14 CRK11976.1 - 0.019 15.0 0.1 0.079 13.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF624 DUF4440 PF14534.6 CRK11976.1 - 3 8.3 4.5 78 3.7 0.0 3.5 4 1 0 4 4 4 0 Domain of unknown function (DUF4440) tRNA-synt_1g PF09334.11 CRK11978.1 - 2.7e-88 296.3 0.4 2.2e-87 293.3 0.4 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (M) Acetyltransf_3 PF13302.7 CRK11978.1 - 6.7e-22 78.7 0.0 1.6e-21 77.4 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain tRNA-synt_1 PF00133.22 CRK11978.1 - 2.7e-18 65.6 6.2 8.4e-07 27.6 0.0 3.6 1 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 CRK11978.1 - 2.6e-08 33.6 0.0 0.0034 16.8 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Acetyltransf_8 PF13523.6 CRK11978.1 - 0.00012 21.8 0.5 0.91 9.2 0.0 3.6 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain tRNA-synt_1f PF01921.18 CRK11978.1 - 0.033 13.1 0.0 0.055 12.4 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (K) Acetyltransf_1 PF00583.25 CRK11978.1 - 0.049 13.9 0.0 1.9 8.8 0.0 2.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family PALP PF00291.25 CRK11981.1 - 3.2e-63 213.9 1.2 5.1e-63 213.2 1.2 1.3 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Ppx-GppA PF02541.16 CRK11983.1 - 1.3e-41 142.9 0.0 6.6e-41 140.6 0.0 2.0 1 1 0 1 1 1 1 Ppx/GppA phosphatase family GDA1_CD39 PF01150.17 CRK11983.1 - 0.13 10.9 0.0 0.22 10.1 0.0 1.3 1 0 0 1 1 1 0 GDA1/CD39 (nucleoside phosphatase) family DNA_pol_E_B PF04042.16 CRK11987.1 - 3.9e-48 163.6 0.0 5.3e-48 163.2 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 CRK11987.1 - 2.6e-39 134.3 0.0 4.1e-39 133.7 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain CENP-I PF07778.11 CRK11990.1 - 1.6e-23 83.2 0.0 1.9e-16 59.9 0.0 3.0 1 1 1 2 2 2 2 Mis6 Ish1 PF10281.9 CRK11992.1 - 6.4e-05 23.2 0.0 0.00012 22.3 0.0 1.5 2 0 0 2 2 2 1 Putative stress-responsive nuclear envelope protein DNA_meth_N PF18284.1 CRK11992.1 - 0.14 12.0 0.8 0.32 10.9 0.2 1.8 2 0 0 2 2 2 0 DNA methylase N-terminal domain Peptidase_M48_N PF16491.5 CRK11994.1 - 6.8e-54 182.5 4.6 6.8e-54 182.5 4.6 1.8 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 CRK11994.1 - 2.5e-39 135.1 0.3 4.4e-39 134.3 0.3 1.3 1 0 0 1 1 1 1 Peptidase family M48 Ribosomal_L34 PF00468.17 CRK11997.1 - 7.8e-11 41.8 10.7 1.3e-10 41.1 10.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L34 Peptidase_M16_C PF05193.21 CRK11999.1 - 4.4e-20 72.5 0.0 1.8e-16 60.7 0.0 2.6 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 CRK11999.1 - 4.3e-07 30.0 0.1 2e-06 27.8 0.0 2.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) M16C_assoc PF08367.11 CRK11999.1 - 0.002 17.3 3.1 0.43 9.7 2.2 2.4 2 0 0 2 2 2 2 Peptidase M16C associated Zw10 PF06248.13 CRK12001.1 - 1.1e-07 30.9 1.4 5.2e-06 25.3 1.4 2.7 2 1 0 2 2 2 1 Centromere/kinetochore Zw10 Anticodon_1 PF08264.13 CRK12001.1 - 0.028 14.4 0.1 5 7.1 0.0 2.6 2 0 0 2 2 2 0 Anticodon-binding domain of tRNA Dsl1_C PF11989.8 CRK12001.1 - 0.077 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Retrograde transport protein Dsl1 C terminal Nop14 PF04147.12 CRK12001.1 - 2.7 6.1 7.5 4.8 5.3 7.5 1.3 1 0 0 1 1 1 0 Nop14-like family PI-PLC-Y PF00387.19 CRK12004.1 - 1.4e-11 44.7 0.1 2.6e-11 43.9 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 CRK12004.1 - 1e-06 29.0 0.0 2.6e-06 27.6 0.0 1.7 1 1 0 1 1 1 1 C2 domain adh_short PF00106.25 CRK12008.1 - 7.6e-35 120.1 0.0 1.1e-34 119.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK12008.1 - 7.2e-27 94.5 0.0 9.4e-27 94.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK12008.1 - 0.0001 22.3 0.1 0.00031 20.7 0.1 1.8 2 0 0 2 2 2 1 KR domain ADH_zinc_N PF00107.26 CRK12008.1 - 0.015 15.2 0.0 0.032 14.2 0.0 1.5 2 0 0 2 2 2 0 Zinc-binding dehydrogenase 3HCDH_N PF02737.18 CRK12008.1 - 0.027 14.4 0.2 0.06 13.2 0.2 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 CRK12008.1 - 0.046 13.1 0.0 0.18 11.1 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 CRK12008.1 - 0.06 12.8 0.2 0.12 11.8 0.2 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Phage_XkdX PF09693.10 CRK12008.1 - 0.092 12.8 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 Phage uncharacterised protein (Phage_XkdX) bZIP_1 PF00170.21 CRK12013.1 - 0.03 14.4 7.8 0.053 13.6 7.8 1.3 1 0 0 1 1 1 0 bZIP transcription factor DUF3390 PF11870.8 CRK12013.1 - 0.046 14.1 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3390) bZIP_2 PF07716.15 CRK12013.1 - 2.9 8.0 8.5 4.2 7.5 8.5 1.2 1 0 0 1 1 1 0 Basic region leucine zipper Pol_alpha_B_N PF08418.10 CRK12015.1 - 7.2e-89 298.0 0.6 9.3e-89 297.6 0.6 1.1 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.16 CRK12015.1 - 2.1e-40 138.4 0.1 2.9e-40 137.9 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DUF4316 PF14195.6 CRK12015.1 - 0.046 13.5 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4316) MFAP1 PF06991.11 CRK12017.1 - 2e-65 220.7 24.2 2e-65 220.7 24.2 3.4 2 2 1 3 3 3 1 Microfibril-associated/Pre-mRNA processing Astro_capsid_p PF12226.8 CRK12017.1 - 0.0053 16.0 3.3 0.0053 16.0 3.3 2.2 2 1 0 2 2 2 1 Turkey astrovirus capsid protein Alb1 PF09135.11 CRK12018.1 - 1e-26 93.8 15.9 1e-26 93.8 15.9 1.7 2 0 0 2 2 2 1 Alb1 Spc7 PF08317.11 CRK12018.1 - 0.89 8.4 4.9 1.1 8.0 4.6 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein TPT PF03151.16 CRK12020.1 - 7.5e-26 91.1 20.5 7.5e-26 91.1 20.5 1.4 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.11 CRK12020.1 - 0.0017 17.6 20.6 0.0029 16.8 20.6 1.4 1 0 0 1 1 1 1 UAA transporter family COMPASS-Shg1 PF05205.12 CRK12023.1 - 8.1e-26 90.7 0.1 8.1e-26 90.7 0.1 2.2 3 0 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component shg1 UL42 PF17638.2 CRK12023.1 - 8.1 6.4 7.9 24 4.9 7.9 1.8 1 0 0 1 1 1 0 HCMV UL42 Glyco_hydro_76 PF03663.14 CRK12024.1 - 2.2e-118 396.0 12.2 2.6e-118 395.7 12.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 CRK12024.1 - 6.9e-06 25.4 5.5 0.035 13.2 0.1 3.1 2 1 1 3 3 3 3 Glycosyl Hydrolase Family 88 Lactonase PF10282.9 CRK12026.1 - 0.00011 21.7 0.6 0.032 13.5 0.0 2.9 2 1 0 2 2 2 2 Lactonase, 7-bladed beta-propeller VioE PF18234.1 CRK12026.1 - 0.18 11.9 0.0 4 7.5 0.0 2.1 2 0 0 2 2 2 0 Violacein biosynthetic enzyme VioE LEA_2 PF03168.13 CRK12027.1 - 0.0013 19.3 20.1 0.0057 17.2 6.0 3.4 2 1 1 3 3 3 2 Late embryogenesis abundant protein Big_7 PF17957.1 CRK12027.1 - 0.76 10.6 9.8 1.5 9.7 0.2 4.2 3 1 0 3 3 3 0 Bacterial Ig domain DUF1943 PF09172.11 CRK12027.1 - 0.9 8.7 14.7 0.37 10.0 7.8 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF1943) PP2C_C PF07830.13 CRK12027.1 - 6.1 7.4 7.7 0.35 11.3 0.9 2.4 2 1 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain bZIP_1 PF00170.21 CRK12028.1 - 0.014 15.4 7.2 0.025 14.7 7.2 1.3 1 0 0 1 1 1 0 bZIP transcription factor DUF3390 PF11870.8 CRK12028.1 - 0.14 12.6 0.0 0.31 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3390) bZIP_2 PF07716.15 CRK12028.1 - 2.6 8.2 7.9 3.7 7.7 7.9 1.2 1 0 0 1 1 1 0 Basic region leucine zipper Pol_alpha_B_N PF08418.10 CRK12029.1 - 3.8e-89 298.9 0.6 4.8e-89 298.5 0.6 1.1 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.16 CRK12029.1 - 4.7e-40 137.2 0.1 6.6e-40 136.7 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DUF4316 PF14195.6 CRK12029.1 - 0.024 14.4 0.0 0.059 13.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4316) MFAP1 PF06991.11 CRK12030.1 - 3.8e-65 219.8 26.3 3.8e-65 219.8 26.3 3.5 2 2 1 3 3 3 1 Microfibril-associated/Pre-mRNA processing YidC_periplas PF14849.6 CRK12030.1 - 0.081 12.8 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 YidC periplasmic domain Alb1 PF09135.11 CRK12031.1 - 1.5e-26 93.3 16.1 1.5e-26 93.3 16.1 1.7 2 0 0 2 2 2 1 Alb1 Spc7 PF08317.11 CRK12031.1 - 0.24 10.2 4.8 0.32 9.8 4.5 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein Atg14 PF10186.9 CRK12031.1 - 2.4 7.1 4.9 2.9 6.9 4.9 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 UCH PF00443.29 CRK12032.1 - 1e-32 113.7 0.0 2e-32 112.7 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CRK12032.1 - 1.6e-08 34.5 0.0 1.1e-07 31.7 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase TPT PF03151.16 CRK12033.1 - 7.4e-18 64.9 11.4 9.2e-18 64.6 11.4 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family DUF1158 PF06643.11 CRK12033.1 - 1.3 9.6 7.8 0.53 10.8 0.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1158) COMPASS-Shg1 PF05205.12 CRK12034.1 - 1.4e-25 89.9 0.1 1.4e-25 89.9 0.1 2.1 3 0 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component shg1 Glyco_hydro_76 PF03663.14 CRK12035.1 - 9.5e-153 509.0 6.1 1.1e-152 508.8 6.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 CRK12035.1 - 5.5e-05 22.4 6.2 0.12 11.4 0.1 3.1 2 1 1 3 3 3 3 Glycosyl Hydrolase Family 88 ECH_2 PF16113.5 CRK12036.1 - 1.5e-126 422.4 0.0 2.3e-126 421.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Dak1 PF02733.17 CRK12036.1 - 9.7e-106 353.2 8.6 1.6e-105 352.5 8.6 1.3 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 CRK12036.1 - 9.1e-46 155.9 2.8 2.7e-45 154.4 2.8 1.9 1 0 0 1 1 1 1 DAK2 domain ECH_1 PF00378.20 CRK12036.1 - 2.2e-27 96.0 0.0 2e-26 92.8 0.0 2.2 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase LSM PF01423.22 CRK12037.1 - 6.5e-18 64.2 0.1 8.8e-18 63.8 0.1 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 CRK12037.1 - 0.13 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Hfq protein GATA PF00320.27 CRK12038.1 - 0.0021 17.6 8.3 0.062 12.9 3.3 2.6 2 0 0 2 2 2 2 GATA zinc finger PBP PF01161.20 CRK12039.1 - 1.9e-09 37.9 0.0 3.8e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Dak1 PF02733.17 CRK12040.1 - 5.2e-106 354.1 9.2 7.4e-106 353.5 9.2 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 CRK12040.1 - 9.1e-46 155.9 2.9 9.1e-46 155.9 2.9 1.9 2 0 0 2 2 2 1 DAK2 domain DUF1442 PF07279.11 CRK12040.1 - 2.5 7.3 5.7 3.8 6.8 1.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1442) LSM PF01423.22 CRK12041.1 - 6.5e-18 64.2 0.1 8.8e-18 63.8 0.1 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 CRK12041.1 - 0.13 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Hfq protein bZIP_1 PF00170.21 CRK12045.1 - 6.1e-13 48.7 1.5 6.1e-13 48.7 1.5 2.2 3 0 0 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.15 CRK12045.1 - 1.6e-09 37.7 0.7 5e-09 36.1 0.7 1.9 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 CRK12045.1 - 0.0009 19.7 2.1 0.0009 19.7 2.1 2.3 2 0 0 2 2 2 1 bZIP Maf transcription factor NAM-associated PF14303.6 CRK12045.1 - 0.015 16.0 10.6 0.024 15.4 10.6 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain TMEM237 PF15383.6 CRK12045.1 - 0.052 12.6 1.0 0.084 12.0 1.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 237 CENP-H PF05837.12 CRK12045.1 - 1.8 9.0 5.7 1.2 9.6 1.7 2.2 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DUF4551 PF15087.6 CRK12045.1 - 9.7 4.9 10.6 12 4.5 10.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Rep_fac-A_3 PF08661.11 CRK12046.1 - 4.6e-20 71.9 0.0 5e-20 71.8 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 Peptidase_M43 PF05572.13 CRK12047.1 - 2.6e-12 46.9 0.0 3.9e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 CRK12047.1 - 0.00061 20.0 0.1 0.00098 19.3 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 DUF4953 PF16313.5 CRK12047.1 - 0.0053 16.0 1.0 0.029 13.6 0.4 1.9 2 0 0 2 2 2 1 Met-zincin Reprolysin_3 PF13582.6 CRK12047.1 - 0.008 16.7 0.0 0.012 16.1 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 CRK12047.1 - 0.024 14.5 0.1 0.034 14.0 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 CRK12047.1 - 0.053 13.2 0.0 0.075 12.7 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like PNP_phzG_C PF10590.9 CRK12047.1 - 0.097 12.8 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Glyco_hydro_61 PF03443.14 CRK12048.1 - 1e-51 175.8 0.0 1.2e-51 175.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Beta_helix PF13229.6 CRK12049.1 - 2.1e-11 43.9 18.8 7.9e-09 35.6 5.5 3.1 1 1 2 3 3 3 2 Right handed beta helix region Chondroitinas_B PF14592.6 CRK12049.1 - 3.1e-06 26.3 0.1 7.9e-06 25.0 0.1 1.6 1 0 0 1 1 1 1 Chondroitinase B DUF1565 PF07602.11 CRK12049.1 - 0.009 15.4 0.6 0.009 15.4 0.6 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF1565) GMC_oxred_N PF00732.19 CRK12050.1 - 1.3e-38 133.1 0.0 3.9e-37 128.2 0.0 2.0 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CRK12050.1 - 3.4e-27 95.8 0.0 6.7e-27 94.8 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 CRK12050.1 - 0.00031 20.4 5.8 0.0018 18.0 5.8 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CRK12050.1 - 0.00041 20.5 0.1 0.0016 18.6 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CRK12050.1 - 0.00046 19.5 0.2 0.0011 18.2 0.1 1.6 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 CRK12050.1 - 0.0015 17.7 0.8 0.0015 17.7 0.8 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 CRK12050.1 - 0.01 15.1 0.2 0.016 14.5 0.2 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 CRK12050.1 - 0.022 15.0 1.3 0.074 13.3 0.3 2.2 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox_2 PF07992.14 CRK12050.1 - 0.048 12.9 0.2 0.082 12.1 0.2 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CRK12050.1 - 0.1 12.6 0.5 0.18 11.8 0.5 1.3 1 0 0 1 1 1 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 CRK12050.1 - 0.16 11.0 0.2 0.29 10.1 0.2 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein SRP40_C PF05022.12 CRK12051.1 - 6.4e-21 75.0 0.8 6.4e-21 75.0 0.8 3.7 4 0 0 4 4 4 1 SRP40, C-terminal domain zf-C3HC PF07967.13 CRK12052.1 - 6e-38 129.9 2.9 5.1e-34 117.2 1.5 2.4 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.10 CRK12052.1 - 3.4e-26 91.2 3.1 7.5e-26 90.1 0.1 2.4 2 0 0 2 2 2 1 Rsm1-like MMR_HSR1 PF01926.23 CRK12052.1 - 0.0028 17.7 0.0 0.0093 16.0 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase BIR PF00653.21 CRK12052.1 - 0.0028 18.3 0.1 0.048 14.3 0.1 2.4 2 0 0 2 2 2 1 Inhibitor of Apoptosis domain RNA_helicase PF00910.22 CRK12052.1 - 0.083 13.3 0.0 0.21 12.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.6 CRK12052.1 - 0.12 12.7 0.6 0.45 10.7 0.1 2.2 2 0 0 2 2 2 0 AAA domain Hydrolase PF00702.26 CRK12053.1 - 3.7e-12 47.0 0.1 5.1e-12 46.5 0.1 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CRK12053.1 - 1.8e-06 27.9 0.2 2.9e-06 27.2 0.2 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CRK12054.1 - 1.1e-57 195.7 0.2 4e-30 105.7 0.0 2.4 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 CRK12054.1 - 4.6e-47 159.9 1.1 4.6e-47 159.9 1.1 2.0 2 0 0 2 2 2 1 E1-E2 ATPase HAD PF12710.7 CRK12054.1 - 4.8e-12 46.7 0.0 1e-05 26.0 0.0 2.8 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CRK12054.1 - 7.3e-07 29.2 0.3 3.7e-05 23.6 0.2 3.1 2 1 0 3 3 3 1 haloacid dehalogenase-like hydrolase DUF4392 PF14336.6 CRK12054.1 - 0.014 14.8 0.2 1.4 8.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4392) Importin_rep_3 PF18806.1 CRK12054.1 - 0.036 14.1 0.0 0.096 12.7 0.0 1.6 1 0 0 1 1 1 0 Importin 13 repeat GSH-S_N PF02951.14 CRK12054.1 - 0.11 12.6 0.0 7.7 6.7 0.0 2.6 2 0 0 2 2 2 0 Prokaryotic glutathione synthetase, N-terminal domain HRG PF16954.5 CRK12054.1 - 0.77 10.2 7.6 1.3 9.5 0.3 2.8 2 0 0 2 2 2 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene DUF1449 PF07290.11 CRK12054.1 - 2.3 7.8 5.5 1 8.9 2.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1449) MMR_HSR1 PF01926.23 CRK12055.1 - 0.037 14.1 0.0 0.062 13.4 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CRK12055.1 - 0.12 11.9 0.0 0.47 10.0 0.0 1.7 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain HMA PF00403.26 CRK12056.1 - 5.9e-61 202.8 19.2 3.5e-13 49.8 1.0 7.9 7 0 0 7 7 7 6 Heavy-metal-associated domain E1-E2_ATPase PF00122.20 CRK12056.1 - 3.5e-36 124.4 0.4 3.5e-36 124.4 0.4 2.1 2 0 0 2 2 2 1 E1-E2 ATPase TerY_C PF15616.6 CRK12056.1 - 1.5e-06 28.4 1.4 0.45 10.6 0.0 4.3 4 0 0 4 4 4 2 TerY-C metal binding domain Peptidase_C71 PF12386.8 CRK12056.1 - 0.0014 18.3 0.1 1.4 8.5 0.0 2.6 2 0 0 2 2 2 2 Pseudomurein endo-isopeptidase Pei DUF2703 PF10865.8 CRK12056.1 - 0.0016 18.6 2.1 6.5 7.0 0.0 4.4 4 0 0 4 4 4 2 Domain of unknown function (DUF2703) Flg_hook PF02120.16 CRK12056.1 - 0.0022 17.9 0.0 5.5 7.0 0.0 3.1 3 0 0 3 3 3 2 Flagellar hook-length control protein FliK Gln_amidase PF15644.6 CRK12056.1 - 0.0048 17.9 2.6 8.8 7.4 0.0 4.3 4 0 0 4 4 4 1 Papain fold toxin 1, glutamine deamidase Importin_rep_3 PF18806.1 CRK12056.1 - 0.028 14.5 1.8 0.051 13.6 0.0 2.3 3 0 0 3 3 2 0 Importin 13 repeat Fer2_BFD PF04324.15 CRK12056.1 - 0.08 13.3 8.2 1.5e+02 2.8 0.0 7.0 7 0 0 7 7 7 0 BFD-like [2Fe-2S] binding domain SopD PF11047.8 CRK12056.1 - 0.088 12.0 0.2 7.8 5.6 0.0 2.2 2 0 0 2 2 2 0 Salmonella outer protein D SBP_bac_5 PF00496.22 CRK12056.1 - 0.1 11.5 1.9 4.1 6.3 0.2 3.3 4 0 0 4 4 4 0 Bacterial extracellular solute-binding proteins, family 5 Middle Phage_B PF02304.15 CRK12056.1 - 0.12 12.8 0.0 20 5.6 0.0 2.8 2 0 0 2 2 2 0 Scaffold protein B EI24 PF07264.11 CRK12056.1 - 1.5 9.0 5.7 0.51 10.6 2.7 1.7 2 0 0 2 2 2 0 Etoposide-induced protein 2.4 (EI24) Zn_Tnp_IS1 PF03811.13 CRK12056.1 - 2.2 8.1 6.5 29 4.5 0.7 3.5 2 0 0 2 2 2 0 InsA N-terminal domain RE_HaeII PF09554.10 CRK12056.1 - 5.2 6.2 7.5 11 5.2 0.9 2.2 2 0 0 2 2 2 0 HaeII restriction endonuclease CDK2AP PF09806.9 CRK12058.1 - 4.4 7.3 9.9 57 3.7 0.9 3.3 3 0 0 3 3 3 0 Cyclin-dependent kinase 2-associated protein Pkinase PF00069.25 CRK12060.1 - 1.6e-18 67.1 0.1 2.3e-07 30.5 0.1 3.0 3 0 0 3 3 3 3 Protein kinase domain FAD_binding_1 PF00667.20 CRK12062.1 - 1.3e-130 433.6 0.0 4.5e-64 216.1 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain 2OG-FeII_Oxy_2 PF13532.6 CRK12062.1 - 8.5e-52 176.2 0.0 8.3e-28 97.9 0.0 2.6 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily POR PF01558.18 CRK12062.1 - 4.3e-22 79.0 0.3 1e-09 38.7 0.0 2.5 2 0 0 2 2 2 2 Pyruvate ferredoxin/flavodoxin oxidoreductase NAD_binding_1 PF00175.21 CRK12062.1 - 3.1e-09 37.4 0.0 1e-08 35.8 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain PFOR_II PF17147.4 CRK12062.1 - 6.4e-07 29.6 0.1 2.8e-06 27.6 0.1 2.2 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Lipoprotein_10 PF03202.13 CRK12062.1 - 0.00014 22.3 0.0 1.1 9.7 0.0 2.5 2 0 0 2 2 2 2 Putative mycoplasma lipoprotein, C-terminal region DUF4349 PF14257.6 CRK12062.1 - 0.014 14.8 0.0 5.1 6.5 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) Transketolase_C PF02780.20 CRK12062.1 - 0.023 14.6 0.2 0.067 13.1 0.2 1.7 1 0 0 1 1 1 0 Transketolase, C-terminal domain WD40_4 PF16300.5 CRK12062.1 - 0.027 14.4 0.0 7.4 6.5 0.0 2.6 2 0 0 2 2 2 0 Type of WD40 repeat FAD_binding_6 PF00970.24 CRK12062.1 - 0.046 14.1 0.0 4.3 7.7 0.0 3.6 4 0 0 4 4 4 0 Oxidoreductase FAD-binding domain DDE_5 PF13546.6 CRK12062.1 - 0.097 12.0 0.1 12 5.1 0.0 2.3 2 0 0 2 2 2 0 DDE superfamily endonuclease PCP_red PF08369.10 CRK12062.1 - 0.13 12.5 1.7 26 5.1 0.1 3.2 3 0 0 3 3 3 0 Proto-chlorophyllide reductase 57 kD subunit DUF5610 PF18433.1 CRK12062.1 - 0.33 11.5 2.5 0.76 10.3 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF5610) NAD_binding_1 PF00175.21 CRK12063.1 - 0.0082 16.8 0.1 0.17 12.6 0.0 2.7 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain C-C_Bond_Lyase PF15617.6 CRK12063.1 - 0.16 11.1 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 C-C_Bond_Lyase of the TIM-Barrel fold Peptidase_S58 PF03576.14 CRK12065.1 - 9.8e-109 363.5 1.6 1.1e-71 241.9 0.2 2.2 2 0 0 2 2 2 2 Peptidase family S58 FAR1 PF03101.15 CRK12065.1 - 8.9e-05 23.1 0.0 8.9e-05 23.1 0.0 2.5 2 1 0 2 2 2 1 FAR1 DNA-binding domain Med15 PF09606.10 CRK12065.1 - 1.6 7.4 55.7 2.4 6.7 55.7 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Fe-ADH PF00465.19 CRK12066.1 - 2.1e-98 329.5 0.1 2.6e-98 329.2 0.1 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 CRK12066.1 - 3.5e-14 53.1 0.0 4.6e-11 42.9 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.6 CRK12066.1 - 0.033 13.8 0.1 0.06 13.0 0.1 1.4 1 0 0 1 1 1 0 Periplasmic binding protein Sec3_C PF09763.9 CRK12067.1 - 3.5e-242 805.8 1.9 4.4e-242 805.5 1.9 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3_C_2 PF15278.6 CRK12067.1 - 0.0037 17.6 0.3 0.013 15.8 0.0 2.1 2 0 0 2 2 2 1 Sec3 exocyst complex subunit Vps52 PF04129.12 CRK12067.1 - 0.018 13.8 0.5 0.11 11.2 0.0 2.2 2 0 0 2 2 2 0 Vps52 / Sac2 family Spc7 PF08317.11 CRK12070.1 - 1.1e-06 27.7 314.6 1.9e-05 23.7 18.5 13.1 1 1 13 14 14 14 11 Spc7 kinetochore protein Fungal_TACC PF12709.7 CRK12070.1 - 0.0022 18.4 1.9 0.0022 18.4 1.9 15.8 7 6 12 21 21 21 2 Fungal Transforming acidic coiled-coil (TACC) proteins Tup_N PF08581.10 CRK12070.1 - 0.46 10.8 163.9 0.25 11.6 1.8 21.0 9 4 10 22 22 22 0 Tup N-terminal DUF4250 PF14056.6 CRK12070.1 - 2.7 8.0 11.1 8.9 6.4 0.1 6.2 4 1 0 4 4 4 0 Domain of unknown function (DUF4250) Aminotran_1_2 PF00155.21 CRK12071.1 - 4.2e-40 138.0 0.0 5.1e-40 137.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II MFS_1 PF07690.16 CRK12073.1 - 2.1e-14 53.3 23.3 2.1e-14 53.3 23.3 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Apelin PF15360.6 CRK12076.1 - 0.047 14.3 2.7 6.7 7.4 1.5 2.8 2 0 0 2 2 2 0 APJ endogenous ligand MFS_1 PF07690.16 CRK12081.1 - 3.6e-20 72.2 19.7 1.4e-12 47.3 7.1 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily DUF5391 PF17369.2 CRK12081.1 - 0.14 12.2 1.1 1.1 9.3 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5391) VHS PF00790.19 CRK12082.1 - 4.3e-24 85.0 0.0 8.1e-24 84.1 0.0 1.4 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 CRK12082.1 - 1.6e-07 31.5 1.1 3.7e-07 30.3 1.1 1.6 1 0 0 1 1 1 1 GAT domain SR-25 PF10500.9 CRK12082.1 - 0.74 9.4 13.6 1.3 8.6 13.6 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein GTP_EFTU PF00009.27 CRK12083.1 - 8.1e-47 159.3 0.0 1.2e-46 158.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.10 CRK12083.1 - 6.4e-22 77.6 0.3 1.4e-21 76.6 0.3 1.5 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU_D2 PF03144.25 CRK12083.1 - 3.3e-10 40.2 0.4 8.4e-10 38.9 0.4 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CRK12083.1 - 4.7e-10 39.5 0.0 5.6e-06 26.4 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU_D3 PF03143.17 CRK12083.1 - 4.7e-07 30.1 0.1 1.3e-06 28.6 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain Roc PF08477.13 CRK12083.1 - 0.00018 21.7 0.1 0.017 15.3 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Septin PF00735.18 CRK12083.1 - 0.012 15.0 0.0 0.019 14.2 0.0 1.2 1 0 0 1 1 1 0 Septin Ras PF00071.22 CRK12083.1 - 0.022 14.4 0.1 0.23 11.0 0.0 2.2 2 0 0 2 2 2 0 Ras family SRPRB PF09439.10 CRK12083.1 - 0.049 13.1 0.0 2.1 7.8 0.0 2.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 CRK12083.1 - 0.11 12.0 0.1 1.6 8.3 0.1 2.5 2 1 0 2 2 2 0 Ferrous iron transport protein B Cpn60_TCP1 PF00118.24 CRK12085.1 - 1e-147 492.7 3.1 1.3e-147 492.4 3.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family His_Phos_1 PF00300.22 CRK12086.1 - 4.6e-15 55.8 0.0 8.9e-15 54.9 0.0 1.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) VHS PF00790.19 CRK12088.1 - 2.2e-41 141.0 3.1 9.2e-41 139.0 0.1 2.2 2 0 0 2 2 2 1 VHS domain FYVE PF01363.21 CRK12088.1 - 1.1e-14 54.3 5.3 2e-14 53.5 5.3 1.4 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.20 CRK12088.1 - 1.6e-05 24.5 15.8 0.0024 17.7 1.5 3.2 3 0 0 3 3 3 2 Ubiquitin interaction motif GAT PF03127.14 CRK12088.1 - 5.4e-05 23.4 0.0 0.00013 22.2 0.0 1.7 1 0 0 1 1 1 1 GAT domain BAF1_ABF1 PF04684.13 CRK12088.1 - 0.58 9.2 3.2 1 8.3 3.2 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor UCH PF00443.29 CRK12089.1 - 5.7e-26 91.6 0.2 6.8e-26 91.3 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CRK12089.1 - 3.8e-16 59.6 1.6 4.5e-16 59.3 1.6 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF3716 PF12511.8 CRK12089.1 - 0.029 14.4 0.4 0.082 13.0 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3716) Cytochrome_C7 PF14522.6 CRK12089.1 - 0.031 14.3 2.1 0.14 12.2 2.1 1.9 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c AMP-binding PF00501.28 CRK12090.1 - 4.4e-28 98.0 0.0 5.7e-28 97.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CRK12090.1 - 0.015 16.2 0.1 0.2 12.7 0.1 2.4 1 1 1 2 2 2 0 AMP-binding enzyme C-terminal domain DASH_Dad3 PF08656.10 CRK12093.1 - 3.6e-19 68.6 0.0 4.1e-19 68.4 0.0 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad3 Helicase_C PF00271.31 CRK12102.1 - 5.5e-12 46.0 0.0 1.2e-11 44.9 0.0 1.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Pkinase PF00069.25 CRK12145.1 - 0.12 11.7 0.0 1.3 8.3 0.0 2.0 2 0 0 2 2 2 0 Protein kinase domain Cnd1 PF12717.7 CRK12146.1 - 1.1e-22 80.8 0.0 1.2e-22 80.6 0.0 1.0 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 LuxT_C PF18285.1 CRK12146.1 - 0.043 14.4 0.1 0.26 11.9 0.0 1.9 1 1 1 2 2 2 0 Tetracycline repressor LuxT C-terminal domain AFOR_N PF02730.15 CRK12148.1 - 0.045 13.6 0.1 0.1 12.5 0.0 1.6 1 1 1 2 2 2 0 Aldehyde ferredoxin oxidoreductase, N-terminal domain Zn_clus PF00172.18 CRK12151.1 - 5.2e-09 36.1 6.7 1e-08 35.2 6.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 CRK12151.1 - 9.7e-05 21.5 0.0 0.00021 20.5 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain DNApol_Exo PF18136.1 CRK12153.1 - 5.1e-104 347.4 0.0 1.6e-103 345.7 0.0 1.8 2 0 0 2 2 2 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 CRK12153.1 - 3.2e-57 194.3 0.0 5.6e-57 193.5 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family A Stc1 PF12898.7 CRK12154.1 - 0.00024 21.6 17.1 0.71 10.5 1.5 5.1 6 0 0 6 6 6 3 Stc1 domain AAA_lid_2 PF17863.1 CRK12154.1 - 0.0033 17.2 0.0 35 4.3 0.0 3.4 3 0 0 3 3 3 0 AAA lid domain LexA_DNA_bind PF01726.16 CRK12154.1 - 0.0063 16.3 0.0 29 4.5 0.0 3.5 3 0 0 3 3 3 0 LexA DNA binding domain F-box PF00646.33 CRK12154.1 - 0.01 15.7 0.4 0.082 12.8 0.1 2.3 2 0 0 2 2 2 0 F-box domain FGE-sulfatase PF03781.16 CRK12154.1 - 0.045 13.3 3.3 2.1 7.9 0.2 2.7 3 0 0 3 3 3 0 Sulfatase-modifying factor enzyme 1 DUF1263 PF06882.12 CRK12154.1 - 0.14 12.2 0.0 1.5e+02 2.5 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1263) PDR_CDR PF06422.12 CRK12154.1 - 0.31 11.0 5.7 49 3.9 0.1 3.6 3 0 0 3 3 3 0 CDR ABC transporter IRF-2BP1_2 PF11261.8 CRK12154.1 - 2.2 7.9 6.7 73 3.0 0.2 3.7 3 0 0 3 3 3 0 Interferon regulatory factor 2-binding protein zinc finger zf-C3HC4_3 PF13920.6 CRK12155.1 - 6.1e-09 35.6 11.2 9.1e-09 35.0 11.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CRK12155.1 - 1.4e-05 24.9 14.1 2e-05 24.3 14.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CRK12155.1 - 1.6e-05 25.1 13.1 2.3e-05 24.6 13.1 1.2 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 CRK12155.1 - 2e-05 24.3 11.5 3.2e-05 23.7 11.5 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CRK12155.1 - 0.00012 21.9 13.2 0.00019 21.3 13.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 CRK12155.1 - 0.00088 19.3 5.3 0.0013 18.7 5.3 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 CRK12155.1 - 0.00093 19.2 9.4 0.001 19.0 6.1 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CRK12155.1 - 0.0025 17.6 14.0 0.0039 17.0 14.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 CRK12155.1 - 0.0071 16.1 9.2 0.014 15.1 9.2 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Baculo_IE-1 PF05290.11 CRK12155.1 - 0.017 15.1 3.8 0.024 14.6 3.8 1.1 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-P11 PF03854.14 CRK12155.1 - 0.14 11.8 6.8 0.23 11.1 6.8 1.3 1 0 0 1 1 1 0 P-11 zinc finger TBCC PF07986.12 CRK12155.1 - 0.21 11.3 3.3 0.3 10.8 3.3 1.2 1 0 0 1 1 1 0 Tubulin binding cofactor C PolC_DP2 PF03833.13 CRK12155.1 - 0.3 8.9 1.0 0.36 8.7 1.0 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DZR PF12773.7 CRK12155.1 - 2.1 8.4 8.5 6.9 6.8 8.6 1.8 1 1 1 2 2 2 0 Double zinc ribbon zf-C3HC4_4 PF15227.6 CRK12155.1 - 2.6 8.3 10.6 4.7 7.5 10.6 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF1272 PF06906.11 CRK12155.1 - 9.8 6.4 10.7 4e+03 -2.0 10.9 2.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) Nup192 PF11894.8 CRK12156.1 - 0 2190.1 13.4 3.9e-208 694.0 0.3 4.0 2 1 2 4 4 4 4 Nuclear pore complex scaffold, nucleoporins 186/192/205 CLU PF13236.6 CRK12156.1 - 0.0013 18.6 0.0 2.1 8.1 0.0 2.3 2 0 0 2 2 2 2 Clustered mitochondria NUP PF06516.11 CRK12156.1 - 0.012 14.8 1.1 4 6.6 0.1 2.5 2 0 0 2 2 2 0 Purine nucleoside permease (NUP) SseB_C PF14581.6 CRK12156.1 - 0.05 13.7 0.0 25 5.0 0.0 3.0 2 0 0 2 2 2 0 SseB protein C-terminal domain Npa1 PF11707.8 CRK12156.1 - 0.058 12.8 0.0 11 5.3 0.0 3.1 2 0 0 2 2 2 0 Ribosome 60S biogenesis N-terminal Op_neuropeptide PF08035.11 CRK12156.1 - 0.073 12.9 0.0 24 4.9 0.0 2.8 2 0 0 2 2 2 0 Opioids neuropeptide pPIWI_RE_Z PF18155.1 CRK12156.1 - 0.088 12.7 0.0 23 4.8 0.0 2.6 2 0 0 2 2 2 0 pPIWI RE three-gene island domain Z DUF4328 PF14219.6 CRK12156.1 - 0.11 12.0 1.1 16 5.0 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4328) Herpes_LP PF03363.13 CRK12156.1 - 0.17 11.7 0.0 28 4.4 0.0 2.4 2 0 0 2 2 2 0 Herpesvirus leader protein Cullin PF00888.22 CRK12157.1 - 4.9e-170 567.1 0.1 8.7e-170 566.3 0.1 1.4 1 0 0 1 1 1 1 Cullin family TAN PF11640.8 CRK12157.1 - 2.7e-44 150.9 3.5 1.7e-43 148.4 0.1 4.1 4 0 0 4 4 4 1 Telomere-length maintenance and DNA damage repair PI3_PI4_kinase PF00454.27 CRK12157.1 - 1.1e-31 110.6 0.0 2.7e-31 109.3 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Cullin_Nedd8 PF10557.9 CRK12157.1 - 6e-22 77.4 0.1 1.7e-21 76.0 0.1 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain FAT PF02259.23 CRK12157.1 - 1.4e-10 41.0 4.3 3.6e-10 39.6 4.3 1.7 1 0 0 1 1 1 1 FAT domain FATC PF02260.20 CRK12157.1 - 2.1e-05 24.3 0.3 5.8e-05 22.8 0.3 1.8 1 0 0 1 1 1 1 FATC domain U1snRNP70_N PF12220.8 CRK12159.1 - 3.4e-26 91.7 3.0 3.4e-26 91.7 3.0 2.4 2 0 0 2 2 2 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 CRK12159.1 - 5.7e-11 42.1 0.2 1e-09 38.0 0.2 2.2 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CRK12159.1 - 0.0032 17.6 0.0 0.0057 16.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif L51_S25_CI-B8 PF05047.16 CRK12160.1 - 2.5e-11 43.3 0.0 4.5e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain TIM PF00121.18 CRK12161.1 - 4e-87 291.6 0.3 4.6e-87 291.4 0.3 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase p450 PF00067.22 CRK12162.1 - 2.3e-52 178.3 0.0 3.3e-52 177.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 CoaE PF01121.20 CRK12163.1 - 3.4e-38 131.1 0.0 7.4e-38 130.0 0.0 1.5 1 1 0 1 1 1 1 Dephospho-CoA kinase Tim17 PF02466.19 CRK12163.1 - 1.4e-23 83.4 4.9 3.5e-23 82.1 4.9 1.8 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family UnbV_ASPIC PF07593.12 CRK12163.1 - 0.056 13.4 0.2 0.29 11.1 0.0 2.2 3 0 0 3 3 3 0 ASPIC and UnbV Gln-synt_C PF00120.24 CRK12164.1 - 5.5e-15 55.2 0.0 7e-11 41.7 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 CRK12164.1 - 2.2e-13 49.8 0.0 3.7e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain MARVEL PF01284.23 CRK12165.1 - 1.5e-17 64.0 1.9 2e-17 63.6 1.9 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF3367 PF11847.8 CRK12165.1 - 0.0032 15.4 0.7 0.0051 14.8 0.7 1.3 1 0 0 1 1 1 1 Alpha-(1->3)-arabinofuranosyltransferase DUF2834 PF11196.8 CRK12166.1 - 0.00048 20.4 7.4 0.0078 16.5 0.4 3.2 3 1 0 3 3 3 2 Protein of unknown function (DUF2834) Cas1_AcylT PF07779.12 CRK12167.1 - 2e-94 317.2 0.6 2.8e-94 316.7 0.6 1.1 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p Pik1 PF11522.8 CRK12168.1 - 1.1e-35 121.4 0.1 1.1e-17 63.7 0.0 3.0 2 0 0 2 2 2 2 Yeast phosphatidylinositol-4-OH kinase Pik1 Say1_Mug180 PF10340.9 CRK12168.1 - 1.5e-18 66.8 0.0 3.9e-13 49.0 0.0 2.2 2 0 0 2 2 2 2 Steryl acetyl hydrolase Abhydrolase_3 PF07859.13 CRK12168.1 - 1.7e-18 67.2 0.1 4.2e-18 66.0 0.1 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold CBFD_NFYB_HMF PF00808.23 CRK12168.1 - 8.4e-11 42.0 1.7 8.4e-11 42.0 1.7 2.3 3 0 0 3 3 3 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PI3Ka PF00613.20 CRK12168.1 - 0.0019 17.7 5.1 0.45 9.9 0.5 2.4 2 0 0 2 2 2 2 Phosphoinositide 3-kinase family, accessory domain (PIK domain) ER_lumen_recept PF00810.18 CRK12168.1 - 0.022 15.6 1.9 8.3 7.2 0.2 2.5 2 0 0 2 2 2 0 ER lumen protein retaining receptor Histone PF00125.24 CRK12168.1 - 0.044 14.1 0.9 0.19 12.1 0.0 2.4 2 1 1 3 3 3 0 Core histone H2A/H2B/H3/H4 HTH_OrfB_IS605 PF12323.8 CRK12168.1 - 0.26 10.8 1.7 23 4.6 0.1 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain RRM_1 PF00076.22 CRK12170.1 - 2.2e-16 59.4 0.0 3.3e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) L31 PF09784.9 CRK12171.1 - 4.1e-46 155.6 0.5 4.6e-46 155.4 0.5 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 Sedlin_N PF04628.13 CRK12172.1 - 3e-47 160.0 0.0 3.5e-47 159.8 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 CRK12172.1 - 2.7e-05 24.1 0.0 0.0018 18.2 0.0 2.1 2 0 0 2 2 2 2 Sybindin-like family DUF4110 PF13422.6 CRK12172.1 - 0.15 12.2 0.1 0.25 11.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4110) CENP-T_C PF15511.6 CRK12173.1 - 8e-09 35.6 0.1 9.7e-09 35.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 CRK12173.1 - 3.5e-05 24.2 0.1 4.1e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 CRK12173.1 - 8.6e-05 22.6 0.1 0.00013 22.1 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 CRK12173.1 - 0.00036 20.7 0.1 0.00065 19.9 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 CRK12173.1 - 0.00042 20.7 0.1 0.00056 20.2 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 CRK12173.1 - 0.0087 16.1 0.0 0.01 15.9 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 CRK12173.1 - 0.023 14.7 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 CRK12173.1 - 0.095 12.5 0.1 0.12 12.2 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) HIGH_NTase1_ass PF16581.5 CRK12173.1 - 0.11 12.5 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region TPR_2 PF07719.17 CRK12174.1 - 2e-37 124.2 26.1 3.1e-06 26.9 0.0 10.5 11 0 0 11 11 10 7 Tetratricopeptide repeat TPR_1 PF00515.28 CRK12174.1 - 2.6e-35 118.8 14.9 4.1e-06 26.4 0.0 9.1 10 0 0 10 10 9 7 Tetratricopeptide repeat ANAPC3 PF12895.7 CRK12174.1 - 2e-29 101.6 16.8 2.3e-20 72.6 0.1 6.1 4 1 2 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 CRK12174.1 - 2.6e-25 86.5 10.1 0.004 17.2 0.1 10.4 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_12 PF13424.6 CRK12174.1 - 3.5e-22 78.5 22.5 0.0043 17.3 0.1 9.2 6 3 2 8 8 8 6 Tetratricopeptide repeat TPR_11 PF13414.6 CRK12174.1 - 2e-18 65.8 8.7 1.6e-06 27.7 1.9 8.7 4 2 5 9 9 9 5 TPR repeat TPR_7 PF13176.6 CRK12174.1 - 3.5e-18 64.2 5.4 0.08 13.0 0.0 7.7 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.6 CRK12174.1 - 4.1e-18 64.5 20.5 0.014 16.2 0.1 10.1 6 3 5 11 11 10 5 Tetratricopeptide repeat TPR_19 PF14559.6 CRK12174.1 - 4.4e-18 65.6 17.6 4.7e-05 23.8 0.0 7.1 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 CRK12174.1 - 2.1e-17 63.5 26.6 6.1e-07 30.0 0.3 8.0 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.6 CRK12174.1 - 1.4e-16 59.6 7.0 0.015 15.6 0.2 9.2 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_6 PF13174.6 CRK12174.1 - 6.8e-09 35.8 16.2 0.65 10.8 0.0 9.2 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_9 PF13371.6 CRK12174.1 - 2.6e-07 30.7 8.9 0.21 11.8 1.6 5.8 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_15 PF13429.6 CRK12174.1 - 7.5e-05 22.1 13.3 0.16 11.2 0.9 4.2 2 1 1 4 4 4 2 Tetratricopeptide repeat TPR_4 PF07721.14 CRK12174.1 - 0.0004 20.7 1.1 3.2 8.7 1.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat DUF2225 PF09986.9 CRK12174.1 - 0.0012 18.6 3.8 1.6 8.4 0.1 3.6 4 0 0 4 4 3 2 Uncharacterized protein conserved in bacteria (DUF2225) TPR_20 PF14561.6 CRK12174.1 - 0.072 13.4 6.6 1.1 9.6 2.4 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat PknG_TPR PF16918.5 CRK12174.1 - 0.11 11.2 3.0 0.17 10.6 0.2 2.3 1 1 1 2 2 2 0 Protein kinase G tetratricopeptide repeat Fis1_TPR_C PF14853.6 CRK12174.1 - 0.17 12.0 2.8 45 4.2 0.0 4.7 5 0 0 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat TMEM208_SND2 PF05620.11 CRK12175.1 - 4.6e-54 182.7 0.1 5.1e-54 182.5 0.1 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 EBP PF05241.12 CRK12176.1 - 3.8e-53 179.6 6.6 6.5e-53 178.8 6.6 1.4 1 0 0 1 1 1 1 Emopamil binding protein PBP PF01161.20 CRK12177.1 - 9.6e-12 45.4 0.0 1.9e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein PBP-Tp47_a PF14889.6 CRK12177.1 - 0.21 11.2 0.0 0.35 10.5 0.0 1.3 1 0 0 1 1 1 0 Penicillin-binding protein Tp47 domain a AAA_lid_2 PF17863.1 CRK12177.1 - 1.5 8.7 5.0 0.73 9.7 1.8 2.1 2 0 0 2 2 2 0 AAA lid domain DUF3669 PF12417.8 CRK12178.1 - 4.6e-15 55.6 0.1 6e-15 55.2 0.1 1.2 1 0 0 1 1 1 1 Zinc finger protein Fungal_trans PF04082.18 CRK12179.1 - 3.5e-12 45.9 0.8 9.7e-12 44.5 0.8 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK12179.1 - 2.4e-10 40.3 11.8 3.9e-10 39.7 11.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Homeobox_KN PF05920.11 CRK12181.1 - 7.5e-42 141.0 6.3 3.3e-20 71.7 0.6 2.7 2 0 0 2 2 2 2 Homeobox KN domain Homeodomain PF00046.29 CRK12181.1 - 2.2e-16 59.4 9.4 1e-07 31.7 1.4 2.6 2 0 0 2 2 2 2 Homeodomain HTH_26 PF13443.6 CRK12181.1 - 0.023 15.2 0.1 13 6.3 0.0 2.4 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain MRP-63 PF14978.6 CRK12181.1 - 0.039 14.6 2.7 1.3e+02 3.3 0.0 4.6 4 0 0 4 4 4 0 Mitochondrial ribosome protein 63 Homez PF11569.8 CRK12181.1 - 0.065 12.7 0.9 21 4.7 0.0 3.3 2 2 2 4 4 4 0 Homeodomain leucine-zipper encoding, Homez 2OG-FeII_Oxy_3 PF13640.6 CRK12182.1 - 1.1e-07 32.6 0.8 8.8e-07 29.7 0.8 2.1 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fungal_trans_2 PF11951.8 CRK12183.1 - 7.8e-05 21.6 0.3 0.00012 21.0 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain SOG2 PF10428.9 CRK12183.1 - 1.8 7.7 13.3 2.7 7.1 13.3 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein CorA PF01544.18 CRK12188.1 - 0.00049 19.5 1.1 0.00061 19.2 1.1 1.3 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Peptidase_M49 PF03571.15 CRK12220.1 - 1.9e-25 89.3 0.0 2.4e-25 88.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M49 AAA_2 PF07724.14 CRK12220.1 - 1.1e-17 64.6 0.0 1.9e-17 63.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 CRK12220.1 - 0.0035 17.8 0.0 0.0056 17.1 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CRK12220.1 - 0.013 15.9 0.0 0.022 15.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 CRK12220.1 - 0.019 15.0 0.0 0.04 13.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 CRK12220.1 - 0.031 14.8 0.0 0.08 13.4 0.0 1.7 2 0 0 2 2 2 0 ABC transporter AAA_22 PF13401.6 CRK12220.1 - 0.047 14.0 0.0 0.11 12.8 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 CRK12220.1 - 0.048 14.2 0.0 0.083 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 CRK12220.1 - 0.058 13.0 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain PduV-EutP PF10662.9 CRK12220.1 - 0.072 12.8 0.0 0.16 11.7 0.0 1.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.22 CRK12220.1 - 0.08 13.3 0.0 0.29 11.5 0.0 2.0 2 1 1 3 3 3 0 RNA helicase AAA_7 PF12775.7 CRK12220.1 - 0.087 12.3 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region NTPase_1 PF03266.15 CRK12220.1 - 0.14 12.1 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 NTPase F1F0-ATPsyn_F PF10791.9 CRK12228.1 - 2.5e-15 56.7 0.1 2.7e-15 56.6 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi Chorismate_bind PF00425.18 CRK12235.1 - 2.4e-09 37.2 0.2 2.5e-09 37.1 0.2 1.0 1 0 0 1 1 1 1 chorismate binding enzyme AAA_17 PF13207.6 CRK12235.1 - 0.052 14.0 0.0 0.058 13.8 0.0 1.0 1 0 0 1 1 1 0 AAA domain DUF1905 PF08922.11 CRK12235.1 - 0.14 12.2 0.0 0.17 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1905) Glyco_hydro_10 PF00331.20 CRK12236.1 - 1.8e-84 283.6 0.0 2.9e-84 282.9 0.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 10 PRELI PF04707.14 CRK12236.1 - 0.011 15.6 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 PRELI-like family GYF_2 PF14237.6 CRK12236.1 - 0.18 11.7 0.4 0.42 10.4 0.4 1.6 1 0 0 1 1 1 0 GYF domain 2 Exo_endo_phos PF03372.23 CRK12237.1 - 1.4e-06 28.0 0.0 3.7e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DCP1 PF06058.13 CRK12238.1 - 1.3e-25 89.6 0.0 1.8e-25 89.1 0.0 1.2 1 0 0 1 1 1 1 Dcp1-like decapping family Hydin_ADK PF17213.3 CRK12238.1 - 0.029 14.7 0.1 0.045 14.0 0.1 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain BAR PF03114.18 CRK12239.1 - 7.7e-67 225.4 4.1 9.7e-67 225.1 4.1 1.1 1 0 0 1 1 1 1 BAR domain CP12 PF02672.15 CRK12239.1 - 0.012 16.4 0.0 0.077 13.7 0.0 2.4 2 1 0 2 2 2 0 CP12 domain SVIP PF15811.5 CRK12239.1 - 1.9 9.0 6.1 0.32 11.5 0.7 2.4 2 1 0 2 2 2 0 Small VCP/p97-interacting protein Prot_ATP_ID_OB PF16450.5 CRK12240.1 - 2.9e-12 46.4 0.1 5.9e-12 45.4 0.1 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain Prot_ATP_OB_N PF17758.1 CRK12240.1 - 0.0028 17.3 0.0 0.0043 16.7 0.0 1.3 1 0 0 1 1 1 1 Proteasomal ATPase OB N-terminal domain tRNA_m1G_MT PF01746.21 CRK12240.1 - 0.13 12.0 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 tRNA (Guanine-1)-methyltransferase Cytochrom_B558a PF05038.13 CRK12240.1 - 0.5 9.9 1.7 0.73 9.4 1.7 1.2 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit UQ_con PF00179.26 CRK12241.1 - 3.7e-38 130.3 0.0 4.8e-38 130.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.10 CRK12241.1 - 1.7e-05 24.5 0.5 3.1e-05 23.7 0.1 1.6 2 0 0 2 2 2 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.6 CRK12241.1 - 0.00052 19.7 0.0 0.00078 19.1 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 CRK12241.1 - 0.046 13.6 0.0 0.075 12.9 0.0 1.3 1 0 0 1 1 1 0 UEV domain CoA_binding PF02629.19 CRK12242.1 - 2.2e-27 95.6 1.2 2.2e-27 95.6 1.2 2.1 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 CRK12242.1 - 8.1e-24 84.2 0.4 1.3e-23 83.5 0.4 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 CRK12242.1 - 2.5e-10 40.3 0.1 4.4e-10 39.5 0.1 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 CRK12242.1 - 8.7e-05 23.0 0.1 0.00034 21.1 0.0 2.0 3 0 0 3 3 3 1 CoA binding domain Radical_SAM_C PF16199.5 CRK12243.1 - 6.6e-33 112.6 0.0 1.2e-32 111.7 0.0 1.5 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 CRK12243.1 - 3e-15 57.0 0.0 1e-14 55.2 0.0 1.9 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 CRK12243.1 - 1.2e-08 35.2 0.0 2.1e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CRK12243.1 - 1.2e-05 25.3 0.0 2.5e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CRK12243.1 - 0.057 13.9 0.0 0.13 12.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Pept_tRNA_hydro PF01195.19 CRK12244.1 - 8.2e-27 94.2 0.0 1e-26 93.9 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase OxoDH_E1alpha_N PF12573.8 CRK12245.1 - 1.8 8.4 4.4 2.5 7.9 0.5 2.4 2 0 0 2 2 2 0 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal Alginate_lyase PF05426.12 CRK12246.1 - 1.5e-06 28.0 3.8 3e-06 27.0 3.8 1.5 1 1 0 1 1 1 1 Alginate lyase Alginate_lyase PF05426.12 CRK12247.1 - 2.4e-06 27.3 8.3 5.1e-06 26.2 8.3 1.4 1 1 0 1 1 1 1 Alginate lyase Glyco_hydro_61 PF03443.14 CRK12248.1 - 2.3e-50 171.4 0.1 2.6e-50 171.2 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Melibiase_2 PF16499.5 CRK12249.1 - 1.9e-53 181.5 3.1 4.7e-53 180.2 3.1 1.6 1 1 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 CRK12249.1 - 5.5e-12 45.6 0.6 1.7e-11 44.0 0.4 2.0 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 CRK12249.1 - 1.9e-08 33.6 0.1 3.4e-08 32.8 0.1 1.3 1 0 0 1 1 1 1 Melibiase Raffinose_syn PF05691.12 CRK12249.1 - 0.0061 14.4 0.0 0.0093 13.8 0.0 1.2 1 0 0 1 1 1 1 Raffinose synthase or seed imbibition protein Sip1 Melibiase_2_C PF17450.2 CRK12249.1 - 0.047 13.9 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Alpha galactosidase A C-terminal beta sandwich domain Fasciclin PF02469.22 CRK12250.1 - 1.9e-12 47.5 0.4 1.4e-11 44.7 0.4 2.1 1 1 0 1 1 1 1 Fasciclin domain DEC-1_N PF04625.13 CRK12250.1 - 0.15 11.1 0.3 0.19 10.7 0.3 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region TauD PF02668.16 CRK12251.1 - 2.5e-34 119.3 0.2 3.3e-34 118.9 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Mac PF12464.8 CRK12252.1 - 5e-17 61.9 0.0 8.2e-17 61.2 0.0 1.4 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.24 CRK12252.1 - 2.4e-12 46.0 12.2 5.6e-12 44.9 4.9 2.9 3 0 0 3 3 3 1 Bacterial transferase hexapeptide (six repeats) GST_N PF02798.20 CRK12252.1 - 6.9e-11 42.3 0.0 1.1e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Hexapep_2 PF14602.6 CRK12252.1 - 1.8e-10 40.4 10.7 6.4e-09 35.4 3.7 3.1 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase GST_N_3 PF13417.6 CRK12252.1 - 8.8e-09 35.7 0.0 1.6e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CRK12252.1 - 4e-06 27.0 0.0 7.1e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CRK12252.1 - 0.0011 19.1 0.0 0.0022 18.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CRK12252.1 - 0.0034 17.4 0.1 0.0083 16.1 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CRK12252.1 - 0.022 14.9 0.0 0.04 14.1 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Abhydrolase_4 PF08386.10 CRK12253.1 - 5.3e-18 65.0 0.0 3.3e-17 62.5 0.0 2.3 3 0 0 3 3 3 1 TAP-like protein Abhydrolase_1 PF00561.20 CRK12253.1 - 1.3e-16 61.0 0.0 3e-15 56.6 0.0 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CRK12253.1 - 0.014 14.6 0.0 0.058 12.7 0.0 2.0 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF4219 PF13961.6 CRK12254.1 - 0.00015 21.4 0.6 0.0017 17.9 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4219) Retrotran_gag_3 PF14244.6 CRK12254.1 - 0.097 12.5 0.2 0.3 11.0 0.0 1.8 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type HTH_18 PF12833.7 CRK12255.1 - 0.061 13.6 0.0 0.17 12.2 0.0 1.7 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_AraC PF00165.23 CRK12255.1 - 0.099 12.8 0.2 6.1 7.1 0.0 2.7 3 0 0 3 3 3 0 Bacterial regulatory helix-turn-helix proteins, AraC family Rhodanese PF00581.20 CRK12256.1 - 2.5e-11 44.0 0.0 3.8e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain HD_3 PF13023.6 CRK12257.1 - 3.9e-47 160.2 0.0 5.1e-47 159.9 0.0 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 CRK12257.1 - 4.9e-09 36.2 0.0 1e-08 35.2 0.0 1.5 1 1 0 1 1 1 1 HD containing hydrolase-like enzyme DUF2284 PF10050.9 CRK12261.1 - 0.012 15.4 66.8 1.9 8.2 0.3 11.7 12 0 0 12 12 12 0 Predicted metal-binding protein (DUF2284) PWI PF01480.17 CRK12263.1 - 9.7e-15 54.7 0.3 2.4e-14 53.4 0.3 1.7 1 0 0 1 1 1 1 PWI domain Ribosomal_S21 PF01165.20 CRK12264.1 - 1.3e-08 34.4 3.5 1.9e-08 33.9 3.5 1.2 1 0 0 1 1 1 1 Ribosomal protein S21 CD24 PF14984.6 CRK12264.1 - 3.3 8.0 6.7 7.5 6.9 6.7 1.7 1 0 0 1 1 1 0 CD24 protein HAUS6_N PF14661.6 CRK12265.1 - 3.2e-56 190.5 0.2 6.1e-56 189.6 0.2 1.5 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus ECH_1 PF00378.20 CRK12266.1 - 4.8e-52 176.8 0.0 6.3e-52 176.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CRK12266.1 - 4.2e-21 75.8 0.0 5.7e-18 65.5 0.1 2.3 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Sugar_tr PF00083.24 CRK12267.1 - 1.1e-103 347.5 14.4 1.3e-103 347.3 14.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK12267.1 - 2.2e-24 86.1 50.5 4.3e-22 78.5 23.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 CRK12267.1 - 0.034 12.5 3.5 0.065 11.5 2.2 1.8 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family YbhQ PF11076.8 CRK12267.1 - 0.12 12.3 0.2 0.12 12.3 0.2 1.8 2 0 0 2 2 2 0 Putative inner membrane protein YbhQ Transketolase_N PF00456.21 CRK12268.1 - 5.1e-131 436.6 0.0 7.4e-131 436.1 0.0 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 CRK12268.1 - 1.1e-36 126.2 0.0 2.5e-36 125.0 0.0 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain DXP_synthase_N PF13292.6 CRK12268.1 - 1.3e-07 31.1 0.0 3e-07 29.9 0.0 1.5 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_C PF02780.20 CRK12268.1 - 2.5e-07 30.6 0.0 5.8e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain E1_dh PF00676.20 CRK12268.1 - 2.7e-07 29.8 0.1 4.6e-07 29.1 0.1 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component Glyco_hydro_28 PF00295.17 CRK12269.1 - 1.3e-47 162.4 0.3 1.8e-47 162.0 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Peptidase_M24 PF00557.24 CRK12270.1 - 4.2e-40 137.7 0.1 6.1e-40 137.1 0.1 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 YL1 PF05764.13 CRK12270.1 - 0.23 11.6 3.4 0.34 11.0 3.4 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Mannitol_dh_C PF08125.13 CRK12273.1 - 1.5e-39 136.0 0.1 2.2e-39 135.5 0.1 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 CRK12273.1 - 1.9e-18 67.1 1.2 6.1e-18 65.4 0.1 2.2 2 1 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain UDPG_MGDP_dh_N PF03721.14 CRK12273.1 - 0.012 15.2 0.5 0.029 13.9 0.2 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 CRK12273.1 - 0.018 14.7 0.4 0.88 9.2 0.0 2.6 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Sacchrp_dh_NADP PF03435.18 CRK12273.1 - 0.12 12.7 0.3 4.6 7.5 0.0 2.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Pkinase PF00069.25 CRK12274.1 - 4.3e-69 232.8 0.0 5.5e-69 232.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK12274.1 - 2.4e-33 115.5 0.0 3.3e-33 115.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 CRK12274.1 - 1.6e-12 47.9 3.1 5.4e-12 46.2 3.1 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 CRK12274.1 - 1.2e-05 24.5 0.1 1.7e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain C2 PF00168.30 CRK12274.1 - 0.007 16.6 0.0 0.015 15.5 0.0 1.5 1 0 0 1 1 1 1 C2 domain Kinase-like PF14531.6 CRK12274.1 - 0.0091 15.3 0.0 0.021 14.1 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 CRK12274.1 - 0.12 11.7 0.2 0.29 10.4 0.1 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family adh_short PF00106.25 CRK12275.1 - 5.2e-34 117.4 0.0 6.6e-34 117.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK12275.1 - 3.8e-26 92.1 0.0 4.6e-26 91.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK12275.1 - 0.0017 18.3 0.0 0.0025 17.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Adeno_52K PF03052.15 CRK12275.1 - 0.072 12.5 0.0 6.9 6.1 0.0 2.1 2 0 0 2 2 2 0 Adenoviral protein L1 52/55-kDa PQ-loop PF04193.14 CRK12276.1 - 4.4e-19 68.0 5.4 1.2e-11 44.2 0.7 3.5 3 1 1 4 4 4 2 PQ loop repeat DUF3087 PF11286.8 CRK12276.1 - 0.12 11.8 2.4 0.25 10.8 2.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) SLATT_1 PF18181.1 CRK12276.1 - 4 7.4 5.9 14 5.6 3.0 2.4 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 L_biotic_typeA PF04604.13 CRK12277.1 - 0.13 12.2 0.1 0.81 9.6 0.0 2.3 2 0 0 2 2 2 0 Type-A lantibiotic WD40 PF00400.32 CRK12277.1 - 2.6 9.0 15.8 9.8 7.2 0.9 5.2 3 2 0 3 3 3 0 WD domain, G-beta repeat peroxidase PF00141.23 CRK12278.1 - 6.6e-21 75.0 0.1 8.9e-20 71.4 0.1 2.1 1 1 0 1 1 1 1 Peroxidase MMS1_N PF10433.9 CRK12280.1 - 1.8e-113 379.8 0.0 2.7e-113 379.2 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 CRK12280.1 - 3.3e-85 286.3 0.0 1.6e-55 188.7 0.0 2.8 3 0 0 3 3 3 2 CPSF A subunit region COesterase PF00135.28 CRK12280.1 - 2e-56 191.9 0.4 7.5e-46 157.1 0.0 2.2 2 0 0 2 2 2 2 Carboxylesterase family DJ-1_PfpI PF01965.24 CRK12280.1 - 4.3e-08 33.1 0.0 1e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 DJ-1/PfpI family Acetyltransf_1 PF00583.25 CRK12280.1 - 1.7e-07 31.5 0.0 4.4e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CRK12280.1 - 3e-06 27.6 0.0 7.3e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CRK12280.1 - 2.3e-05 24.3 0.0 5.7e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Abhydrolase_3 PF07859.13 CRK12280.1 - 0.0015 18.4 0.1 0.0051 16.7 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CRK12280.1 - 0.077 12.5 0.4 0.17 11.3 0.4 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family SnoaL_2 PF12680.7 CRK12280.1 - 0.13 12.9 0.0 1.1 9.9 0.0 2.5 2 0 0 2 2 2 0 SnoaL-like domain ProRS-C_1 PF09180.11 CRK12283.1 - 1.3e-24 86.2 0.1 2e-24 85.6 0.1 1.3 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.20 CRK12283.1 - 2.9e-10 40.2 0.0 5.3e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain ProRS-C_1 PF09180.11 CRK12285.1 - 1e-23 83.3 0.1 2e-23 82.4 0.1 1.5 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 CRK12285.1 - 5.5e-20 72.1 0.0 1.2e-19 71.0 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 CRK12285.1 - 1.7e-17 63.3 0.0 4.2e-17 62.1 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain MT0933_antitox PF14013.6 CRK12285.1 - 0.0026 18.0 20.2 0.34 11.3 6.1 2.9 2 0 0 2 2 2 2 MT0933-like antitoxin protein ParE-like_toxin PF15781.5 CRK12285.1 - 0.0093 15.9 2.6 3.1 7.8 0.2 2.5 2 0 0 2 2 2 2 ParE-like toxin of type II bacterial toxin-antitoxin system AIRS PF00586.24 CRK12285.1 - 0.041 14.5 0.0 66 4.3 0.0 3.5 3 0 0 3 3 3 0 AIR synthase related protein, N-terminal domain MACPF PF01823.19 CRK12285.1 - 0.11 12.6 1.6 7.1 6.7 0.1 2.2 1 1 1 2 2 2 0 MAC/Perforin domain Apelin PF15360.6 CRK12285.1 - 0.14 12.8 0.1 0.39 11.3 0.1 1.7 1 0 0 1 1 1 0 APJ endogenous ligand Tegument_dsDNA PF12818.7 CRK12285.1 - 0.64 9.1 5.4 5.5 6.0 0.1 2.2 2 0 0 2 2 2 0 dsDNA viral tegument protein DUF3123 PF11321.8 CRK12285.1 - 2.4 8.9 14.1 5.9 7.6 2.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3123) Cpn60_TCP1 PF00118.24 CRK12286.1 - 3.7e-162 540.4 19.5 5.4e-121 404.6 7.4 3.0 2 1 1 3 3 3 3 TCP-1/cpn60 chaperonin family PAS PF00989.25 CRK12286.1 - 0.098 12.7 0.1 20 5.3 0.0 2.4 2 0 0 2 2 2 0 PAS fold DP-EP PF08985.11 CRK12286.1 - 0.17 12.1 0.9 29 4.9 0.1 2.9 2 0 0 2 2 2 0 DP-EP family Cpn60_TCP1 PF00118.24 CRK12287.1 - 7.4e-27 94.1 0.2 7.5e-27 94.1 0.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Fungal_trans PF04082.18 CRK12290.1 - 5e-12 45.4 0.0 5.8e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain PP-binding PF00550.25 CRK12299.1 - 0.0015 18.9 0.2 0.0031 17.8 0.2 1.5 1 1 0 1 1 1 1 Phosphopantetheine attachment site Sld5 PF05916.11 CRK12326.1 - 0.0075 16.7 0.0 0.0087 16.5 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein Thiolase_N PF00108.23 CRK12327.1 - 1e-29 103.7 0.4 1.1e-29 103.6 0.4 1.0 1 0 0 1 1 1 1 Thiolase, N-terminal domain Glyco_hydro_45 PF02015.16 CRK12336.1 - 3.5e-77 259.0 15.8 4.2e-77 258.8 15.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 zf-RING_2 PF13639.6 CRK12338.1 - 5.5e-12 45.8 6.7 9.8e-12 45.0 6.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CRK12338.1 - 2.7e-08 33.5 5.5 4.9e-08 32.7 5.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CRK12338.1 - 1.3e-07 31.2 5.7 1.3e-07 31.2 5.7 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 CRK12338.1 - 2.7e-06 27.1 5.9 5e-06 26.3 5.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CRK12338.1 - 4e-06 26.7 5.0 6.9e-06 25.9 5.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CRK12338.1 - 1.1e-05 25.4 2.0 1.1e-05 25.4 2.0 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 CRK12338.1 - 1.8e-05 24.9 3.4 4.6e-05 23.6 3.4 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 CRK12338.1 - 0.0001 22.1 5.3 0.00019 21.2 5.3 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 CRK12338.1 - 0.00021 21.1 4.5 0.00036 20.3 4.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CRK12338.1 - 0.0024 17.9 1.1 0.005 16.9 1.1 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 CRK12338.1 - 0.041 13.5 2.8 0.075 12.7 2.8 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Vps39_2 PF10367.9 CRK12338.1 - 0.11 12.9 1.6 0.25 11.8 0.3 2.1 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 WBP-1 PF11669.8 CRK12338.1 - 0.12 13.1 1.8 0.13 12.9 0.1 2.0 2 0 0 2 2 1 0 WW domain-binding protein 1 zf-C3HC4_4 PF15227.6 CRK12338.1 - 0.2 11.8 6.9 0.4 10.9 6.9 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-HC5HC2H_2 PF13832.6 CRK12338.1 - 0.23 11.6 1.4 0.26 11.5 0.3 1.6 1 1 0 1 1 1 0 PHD-zinc-finger like domain YdjO PF14169.6 CRK12338.1 - 0.5 10.1 2.1 22 4.9 0.2 3.0 2 1 1 3 3 3 0 Cold-inducible protein YdjO Rtf2 PF04641.12 CRK12338.1 - 0.53 9.6 3.4 0.15 11.4 0.1 1.6 2 0 0 2 2 2 0 Rtf2 RING-finger zf-RING_4 PF14570.6 CRK12338.1 - 0.54 10.1 3.9 0.97 9.3 3.9 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.7 CRK12338.1 - 0.8 9.9 3.4 1.5 9.0 3.4 1.5 1 0 0 1 1 1 0 RING-variant domain zf-Nse PF11789.8 CRK12338.1 - 1.6 8.7 4.6 3.4 7.6 4.6 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.8 CRK12338.1 - 1.9 8.7 5.0 11 6.3 5.0 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain TFIIS_M PF07500.14 CRK12340.1 - 1e-26 93.6 0.7 1e-26 93.6 0.7 1.8 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 CRK12340.1 - 1.1e-18 66.7 6.6 2.1e-18 65.9 6.6 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 CRK12340.1 - 4.4e-12 45.8 1.2 9.5e-12 44.8 0.7 1.9 2 0 0 2 2 2 1 TFIIS helical bundle-like domain DFRP_C PF16543.5 CRK12340.1 - 0.14 12.7 3.2 1.1 9.8 0.1 2.4 2 0 0 2 2 2 0 DRG Family Regulatory Proteins, Tma46 zf-ZPR1 PF03367.13 CRK12340.1 - 0.45 10.4 5.8 0.33 10.8 0.4 2.8 2 1 1 3 3 3 0 ZPR1 zinc-finger domain MAGUK_N_PEST PF10608.9 CRK12340.1 - 1.5 9.3 5.0 3.2 8.2 0.8 2.3 2 0 0 2 2 2 0 Polyubiquitination (PEST) N-terminal domain of MAGUK CPSF100_C PF13299.6 CRK12340.1 - 5.5 7.2 7.8 3.5 7.8 0.8 2.6 2 1 1 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal Methyltransf_28 PF02636.17 CRK12341.1 - 6.2e-10 39.1 0.0 9.3e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase tRNA-synt_2c PF01411.19 CRK12342.1 - 2.3e-189 630.5 0.5 3.1e-189 630.1 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 CRK12342.1 - 6.9e-18 64.5 0.4 1.8e-17 63.1 0.4 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 CRK12342.1 - 5.6e-10 39.8 1.7 5.6e-10 39.8 1.7 2.3 2 0 0 2 2 2 1 DHHA1 domain cobW PF02492.19 CRK12342.1 - 0.0088 15.7 0.6 0.015 14.9 0.6 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain DUF5370 PF17340.2 CRK12342.1 - 0.04 13.8 0.1 0.12 12.2 0.1 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5370) Peptidase_C11 PF03415.14 CRK12342.1 - 0.14 11.5 0.7 0.29 10.5 0.7 1.4 1 0 0 1 1 1 0 Clostripain family LprI PF07007.12 CRK12342.1 - 5.3 7.7 7.0 1.3 9.7 1.4 2.7 3 0 0 3 3 3 0 Lysozyme inhibitor LprI SRF-TF PF00319.18 CRK12344.1 - 1.6e-22 78.7 0.3 2.4e-22 78.1 0.3 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF3591 PF12157.8 CRK12345.1 - 2e-173 577.1 2.0 2.8e-173 576.6 2.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC PF00098.23 CRK12345.1 - 0.0037 17.3 1.2 0.0071 16.4 1.2 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 CRK12345.1 - 0.44 10.4 4.0 0.36 10.7 1.7 2.1 2 0 0 2 2 2 0 Zinc knuckle Actin PF00022.19 CRK12346.1 - 5.8e-144 479.7 0.0 6.6e-144 479.5 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 CRK12346.1 - 0.0001 21.2 0.0 0.25 10.1 0.0 2.5 3 0 0 3 3 3 2 MreB/Mbl protein TFIIF_beta PF02270.15 CRK12347.1 - 0.024 14.8 0.0 0.04 14.0 0.0 1.3 1 0 0 1 1 1 0 TFIIF, beta subunit HTH domain Patatin PF01734.22 CRK12348.1 - 4.9e-17 62.8 0.3 4e-16 59.8 0.1 2.4 2 1 0 2 2 2 1 Patatin-like phospholipase PIG-P PF08510.12 CRK12349.1 - 1.1e-52 177.0 2.1 1.5e-52 176.6 2.1 1.2 1 0 0 1 1 1 1 PIG-P DUF485 PF04341.12 CRK12349.1 - 0.043 13.8 0.4 0.043 13.8 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF485 Phage_holin_3_6 PF07332.11 CRK12349.1 - 0.34 11.0 1.0 0.45 10.6 1.0 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DPM2 PF07297.12 CRK12349.1 - 0.62 10.4 11.0 1.2 9.5 11.0 1.4 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) EcKinase PF02958.20 CRK12350.1 - 6.5e-16 58.5 0.0 9.2e-16 58.0 0.0 1.1 1 0 0 1 1 1 1 Ecdysteroid kinase APH PF01636.23 CRK12350.1 - 5.9e-10 39.5 2.3 8.8e-10 38.9 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CRK12350.1 - 0.093 12.3 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1679 PF07914.11 CRK12350.1 - 0.21 10.4 0.0 0.29 10.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) CHRD PF07452.12 CRK12351.1 - 5.9e-11 43.4 0.0 1.2e-10 42.4 0.0 1.4 1 0 0 1 1 1 1 CHRD domain DUF1708 PF08101.11 CRK12352.1 - 5e-156 520.2 0.0 1.9e-155 518.3 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF1708) UDG PF03167.19 CRK12353.1 - 3e-23 82.5 0.0 6.7e-23 81.4 0.0 1.5 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily F-box-like PF12937.7 CRK12355.1 - 9.8e-10 38.2 0.0 1.7e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CRK12355.1 - 0.0009 19.1 0.0 0.0018 18.1 0.0 1.5 1 0 0 1 1 1 1 F-box domain Sulfatase PF00884.23 CRK12357.1 - 1e-55 189.3 0.1 1.3e-55 189.0 0.1 1.1 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.8 CRK12357.1 - 9.6e-26 89.4 1.5 1.8e-25 88.5 0.3 2.0 1 1 1 2 2 2 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.22 CRK12357.1 - 1.4e-07 31.4 0.1 0.0026 17.4 0.0 2.4 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 CRK12357.1 - 0.035 12.7 0.0 0.05 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Med8 PF10232.9 CRK12359.1 - 2.1e-33 115.8 0.3 3e-33 115.3 0.3 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 LPD22 PF18834.1 CRK12359.1 - 0.014 15.6 0.1 7 6.9 0.0 2.5 2 0 0 2 2 2 0 Large polyvalent protein associated domain 22 GCIP PF13324.6 CRK12359.1 - 0.62 9.6 3.9 0.25 10.9 1.2 1.6 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting Sulfatase PF00884.23 CRK12360.1 - 1.4e-55 188.9 0.2 1.7e-55 188.6 0.2 1.1 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.8 CRK12360.1 - 9.8e-26 89.3 1.5 1.8e-25 88.5 0.3 2.0 1 1 1 2 2 2 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.22 CRK12360.1 - 1.6e-07 31.3 0.1 0.0028 17.3 0.1 2.3 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 CRK12360.1 - 0.031 12.9 0.0 0.046 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Med8 PF10232.9 CRK12361.1 - 9.2e-34 117.0 0.3 1.3e-33 116.6 0.3 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 Acyl_transf_3 PF01757.22 CRK12362.1 - 5.2e-25 88.2 25.9 1.3e-24 86.9 25.9 1.6 1 1 0 1 1 1 1 Acyltransferase family TENA_THI-4 PF03070.16 CRK12363.1 - 1.3e-12 47.9 0.0 0.19 11.5 0.0 5.9 6 0 0 6 6 6 3 TENA/THI-4/PQQC family FokI_N PF02981.15 CRK12363.1 - 5.1e-07 29.9 0.2 1.8 8.7 0.0 3.2 3 0 0 3 3 3 3 Restriction endonuclease FokI, recognition domain COMMD1_N PF17221.3 CRK12363.1 - 1.4e-05 25.3 0.0 5.8 7.3 0.0 3.3 3 0 0 3 3 3 3 COMMD1 N-terminal domain IKKbetaNEMObind PF12179.8 CRK12363.1 - 0.001 19.0 0.0 26 5.0 0.0 3.4 3 0 0 3 3 3 0 I-kappa-kinase-beta NEMO binding domain TM2 PF05154.16 CRK12363.1 - 0.0023 18.2 0.7 30 5.1 0.0 3.3 3 0 0 3 3 3 0 TM2 domain Sep15_SelM PF08806.11 CRK12363.1 - 0.12 12.6 0.0 1.3e+02 2.8 0.0 3.2 3 0 0 3 3 3 0 Sep15/SelM redox domain GlutR_dimer PF00745.20 CRK12363.1 - 0.13 12.7 1.9 30 5.1 0.1 3.2 3 0 0 3 3 3 0 Glutamyl-tRNAGlu reductase, dimerisation domain DUF3134 PF11332.8 CRK12363.1 - 0.18 12.2 1.6 1.3e+02 3.0 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3134) GFA PF04828.14 CRK12364.1 - 5.6e-18 65.1 2.1 9.1e-18 64.4 2.1 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DUF1295 PF06966.12 CRK12365.1 - 4.5e-57 193.3 0.3 5.7e-57 192.9 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 CRK12365.1 - 2.8e-07 30.6 0.4 2.8e-07 30.6 0.4 2.9 2 1 2 4 4 4 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 CRK12365.1 - 0.00012 22.4 0.0 0.00012 22.4 0.0 2.7 3 0 0 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 CRK12365.1 - 0.00082 19.7 1.1 0.0032 17.8 0.0 2.6 2 1 0 2 2 2 1 Phospholipid methyltransferase Chi-conotoxin PF16981.5 CRK12366.1 - 1.4 9.2 0.0 1.4 9.2 0.0 3.4 3 1 1 4 4 4 0 chi-Conotoxin or t superfamily RNase_P_p30 PF01876.16 CRK12367.1 - 2.1e-18 66.6 0.0 3.4e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit p30 Chi-conotoxin PF16981.5 CRK12368.1 - 1.4 9.2 0.0 1.4 9.2 0.0 3.0 3 1 0 3 3 3 0 chi-Conotoxin or t superfamily RNase_P_p30 PF01876.16 CRK12369.1 - 1.8e-53 181.2 0.0 2.4e-53 180.8 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit p30 zinc_ribbon_15 PF17032.5 CRK12370.1 - 0.00014 22.5 1.1 0.00021 22.0 1.1 1.2 1 0 0 1 1 1 1 zinc-ribbon family Sel1 PF08238.12 CRK12371.1 - 2e-28 98.2 44.3 0.00012 22.6 0.8 12.6 14 1 0 14 14 14 8 Sel1 repeat TPR_8 PF13181.6 CRK12371.1 - 0.72 10.2 3.5 12 6.4 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 CRK12371.1 - 2.3 8.2 6.3 4.5 7.2 0.2 4.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 CRK12371.1 - 3.1 8.0 6.9 5.4 7.3 0.1 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat AAA_16 PF13191.6 CRK12372.1 - 3.3e-05 24.3 0.0 0.00037 20.9 0.0 2.8 3 1 0 3 3 3 1 AAA ATPase domain NACHT PF05729.12 CRK12372.1 - 6.2e-05 23.0 0.1 0.00034 20.6 0.0 2.3 3 0 0 3 3 3 1 NACHT domain Abhydrolase_6 PF12697.7 CRK12372.1 - 0.0011 19.7 0.6 0.0032 18.1 0.6 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ank_4 PF13637.6 CRK12372.1 - 0.0031 18.0 0.0 0.14 12.8 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeats (many copies) DUF676 PF05057.14 CRK12372.1 - 0.013 15.0 0.0 0.1 12.1 0.0 2.1 2 0 0 2 2 2 0 Putative serine esterase (DUF676) DUF900 PF05990.12 CRK12372.1 - 0.045 13.3 0.0 0.089 12.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Ank_5 PF13857.6 CRK12372.1 - 0.054 13.8 0.0 0.33 11.3 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeats (many copies) RNase_P_p30 PF01876.16 CRK12374.1 - 9.5e-09 35.0 0.0 1.1e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit p30 CD24 PF14984.6 CRK12374.1 - 0.16 12.3 10.1 0.31 11.3 7.3 2.2 2 0 0 2 2 2 0 CD24 protein Sel1 PF08238.12 CRK12376.1 - 3.5e-28 97.4 43.9 0.00013 22.5 0.4 12.7 14 1 0 14 14 14 7 Sel1 repeat DUF2615 PF11027.8 CRK12376.1 - 0.17 12.0 0.0 0.41 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) TPR_8 PF13181.6 CRK12376.1 - 0.74 10.2 3.5 12 6.4 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 CRK12376.1 - 2.5 8.1 6.3 4.5 7.2 0.2 4.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 CRK12376.1 - 3.4 7.9 6.9 5.3 7.3 0.1 4.7 6 0 0 6 6 6 0 Tetratricopeptide repeat WD40 PF00400.32 CRK12377.1 - 8.4e-05 23.3 0.0 0.3 12.0 0.0 3.6 2 0 0 2 2 2 2 WD domain, G-beta repeat NACHT PF05729.12 CRK12377.1 - 0.00012 22.0 0.0 0.00045 20.2 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 CRK12377.1 - 0.00019 21.9 0.1 0.0011 19.4 0.0 2.4 3 0 0 3 3 3 1 AAA ATPase domain Ank_4 PF13637.6 CRK12377.1 - 0.00049 20.6 0.0 0.02 15.5 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Abhydrolase_6 PF12697.7 CRK12377.1 - 0.0025 18.5 1.0 0.0025 18.5 1.0 2.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF676 PF05057.14 CRK12377.1 - 0.022 14.3 0.0 0.12 11.9 0.0 1.9 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Ank_5 PF13857.6 CRK12377.1 - 0.029 14.7 0.0 0.16 12.4 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeats (many copies) DUF900 PF05990.12 CRK12377.1 - 0.064 12.7 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Hydrolase_4 PF12146.8 CRK12377.1 - 0.15 11.3 0.8 0.79 8.9 0.0 2.5 4 0 0 4 4 4 0 Serine aminopeptidase, S33 FRG1 PF06229.12 CRK12379.1 - 3e-49 167.3 0.3 5.2e-49 166.6 0.3 1.3 1 0 0 1 1 1 1 FRG1-like domain Fascin PF06268.13 CRK12379.1 - 0.00085 19.5 0.0 0.0019 18.4 0.0 1.6 1 0 0 1 1 1 1 Fascin domain 2OG-FeII_Oxy PF03171.20 CRK12380.1 - 0.0014 19.1 0.1 0.0068 16.9 0.1 2.1 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fungal_trans PF04082.18 CRK12381.1 - 1.4e-10 40.7 0.0 1.9e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain FeS_assembly_P PF01883.19 CRK12382.1 - 2.3e-06 27.7 0.0 2.7e-05 24.2 0.0 2.2 1 1 0 1 1 1 1 Iron-sulfur cluster assembly protein GTP_EFTU PF00009.27 CRK12383.1 - 6.6e-43 146.5 0.0 9.5e-43 146.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 CRK12383.1 - 8e-35 120.1 4.3 1.6e-34 119.1 4.3 1.5 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 CRK12383.1 - 8.4e-24 83.7 0.0 2e-23 82.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 CRK12383.1 - 6.5e-19 67.8 0.0 1.8e-18 66.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 CRK12383.1 - 1.7e-10 41.2 0.1 1.2e-09 38.4 0.0 2.6 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.6 CRK12383.1 - 3.4e-08 33.5 0.1 5.8e-07 29.5 0.0 2.4 2 0 0 2 2 2 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 CRK12383.1 - 0.00034 20.7 0.1 0.00065 19.8 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Thiolase_N PF00108.23 CRK12384.1 - 4.2e-90 301.6 2.1 6.7e-90 301.0 2.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CRK12384.1 - 5.1e-46 155.3 1.7 6.6e-46 155.0 0.5 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 CRK12384.1 - 0.00011 21.9 0.5 0.00011 21.9 0.5 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 CRK12384.1 - 0.037 13.9 4.0 0.4 10.5 0.1 2.8 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Sin3a_C PF16879.5 CRK12385.1 - 1.2e-71 241.8 2.2 6.3e-71 239.4 1.1 2.7 3 0 0 3 3 3 1 C-terminal domain of Sin3a protein PAH PF02671.21 CRK12385.1 - 7.5e-49 163.6 5.7 4e-18 65.3 2.9 3.7 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 CRK12385.1 - 2.1e-38 130.3 1.2 5.5e-37 125.8 0.0 2.6 2 0 0 2 2 2 1 Sin3 family co-repressor PhageMin_Tail PF10145.9 CRK12385.1 - 0.043 13.7 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 Phage-related minor tail protein Nuf2 PF03800.14 CRK12385.1 - 0.11 12.7 0.5 2 8.5 0.0 2.9 3 0 0 3 3 3 0 Nuf2 family TSP_NTD PF17804.1 CRK12385.1 - 0.25 11.6 0.0 0.25 11.6 0.0 2.9 3 1 0 3 3 3 0 Tail specific protease N-terminal domain FAD_binding_2 PF00890.24 CRK12386.1 - 3.7e-84 283.2 0.9 5.3e-84 282.7 0.9 1.2 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 CRK12386.1 - 3.3e-21 75.2 0.0 3.3e-20 72.0 0.0 2.6 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 CRK12386.1 - 4.9e-14 52.7 0.3 8e-14 52.0 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 CRK12386.1 - 1.3e-09 37.9 1.2 6.2e-09 35.7 1.2 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CRK12386.1 - 6.1e-08 32.2 0.6 9.4e-07 28.3 0.3 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CRK12386.1 - 4.3e-07 30.1 3.3 1e-06 28.9 0.9 2.7 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 CRK12386.1 - 1.6e-06 27.7 0.1 2.7e-06 26.9 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 CRK12386.1 - 4.3e-05 22.4 3.0 0.012 14.4 0.6 3.3 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox_3 PF13738.6 CRK12386.1 - 6.3e-05 22.4 0.0 0.21 10.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CRK12386.1 - 0.00062 19.1 1.8 0.059 12.6 0.8 2.4 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 CRK12386.1 - 0.0072 15.4 2.5 0.13 11.3 1.2 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A Amino_oxidase PF01593.24 CRK12386.1 - 0.021 14.1 1.4 0.29 10.4 0.3 2.8 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 CRK12386.1 - 0.034 13.4 0.6 0.065 12.5 0.6 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 CRK12386.1 - 0.036 14.6 2.9 2 9.0 0.5 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Sugar_tr PF00083.24 CRK12387.1 - 4.4e-123 411.5 17.1 5.1e-123 411.3 17.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK12387.1 - 1.7e-22 79.9 33.1 1.1e-16 60.7 12.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily IBR PF01485.21 CRK12388.1 - 1.7e-13 50.6 30.2 2.7e-09 37.1 7.0 3.5 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 CRK12388.1 - 1.8e-05 24.6 6.5 1.8e-05 24.6 6.5 3.3 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 CRK12388.1 - 6.5e-05 23.2 5.0 6.5e-05 23.2 5.0 3.6 3 0 0 3 3 3 1 Ring finger domain zf-RING_11 PF17123.5 CRK12388.1 - 0.00038 20.1 2.3 0.00038 20.1 2.3 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 CRK12388.1 - 0.00091 19.1 4.0 0.00091 19.1 4.0 3.8 2 1 1 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CRK12388.1 - 0.0011 18.8 2.1 0.0011 18.8 2.1 4.1 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CRK12388.1 - 0.0017 18.2 4.8 0.0017 18.2 4.8 4.5 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Pkinase PF00069.25 CRK12389.1 - 1.6e-58 198.2 0.0 2e-58 197.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK12389.1 - 5.5e-28 97.9 0.0 8e-28 97.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CRK12389.1 - 2.2e-07 30.5 0.0 3e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CRK12389.1 - 0.0024 17.9 0.0 0.59 10.0 0.0 2.9 3 1 1 4 4 4 1 Phosphotransferase enzyme family Kdo PF06293.14 CRK12389.1 - 0.0066 15.8 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CRK12389.1 - 0.2 10.5 0.0 0.32 9.9 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Choline_kinase PF01633.20 CRK12389.1 - 0.24 11.0 0.0 0.47 10.0 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Ribosomal_L31e PF01198.19 CRK12390.1 - 5.3e-16 58.6 0.1 7.5e-16 58.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L31e Ribosomal_L3 PF00297.22 CRK12430.1 - 4.1e-45 154.4 1.4 4.4e-45 154.2 1.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 zf-C2H2 PF00096.26 CRK12441.1 - 0.0005 20.4 21.6 0.0064 16.9 0.8 4.1 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CRK12441.1 - 0.0094 16.3 1.0 0.0094 16.3 1.0 4.1 5 0 0 5 5 5 1 Zinc-finger double domain zf-CHCC PF10276.9 CRK12441.1 - 0.023 14.7 4.5 1.1 9.4 0.3 2.4 2 0 0 2 2 2 0 Zinc-finger domain zf-C2H2_4 PF13894.6 CRK12441.1 - 0.04 14.8 1.9 0.04 14.8 1.9 4.3 4 1 0 4 4 4 0 C2H2-type zinc finger PyrI_C PF02748.15 CRK12441.1 - 0.12 12.3 1.9 6.5 6.7 0.6 2.4 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-ribbon_3 PF13248.6 CRK12441.1 - 0.34 10.4 2.9 16 5.1 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 CRK12441.1 - 0.87 9.8 4.9 1.4 9.1 0.5 2.5 3 0 0 3 3 2 0 Zinc ribbon domain Zn_ribbon_recom PF13408.6 CRK12441.1 - 1.2 9.8 6.4 1.8 9.2 0.4 2.4 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-FCS PF06467.14 CRK12441.1 - 1.5 8.8 6.3 1.3 9.0 0.2 2.8 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif Actin_micro PF17003.5 CRK12441.1 - 2 7.5 7.1 20 4.2 7.1 1.9 1 1 0 1 1 1 0 Putative actin-like family zf-BED PF02892.15 CRK12441.1 - 2.1 8.4 14.6 5.4 7.1 0.5 4.0 3 1 0 3 3 3 0 BED zinc finger zf-C2HC_2 PF13913.6 CRK12441.1 - 3.4 7.7 7.4 1.9 8.5 0.7 2.7 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.7 CRK12441.1 - 8.9 6.7 14.6 1.5 9.2 2.1 3.2 2 2 1 3 3 3 0 C2H2 type zinc-finger (2 copies) LtrA PF06772.11 CRK12442.1 - 1.2e-21 77.3 10.2 1.2e-21 77.3 10.2 2.1 2 0 0 2 2 2 2 Bacterial low temperature requirement A protein (LtrA) Vfa1 PF08432.10 CRK12444.1 - 1.1e-39 136.6 19.8 1.4e-39 136.3 19.8 1.1 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 SpoIIIAH PF12685.7 CRK12444.1 - 0.026 14.3 8.1 0.035 13.9 8.1 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein RNA_pol_Rpc4 PF05132.14 CRK12444.1 - 0.12 12.8 7.8 0.21 12.0 7.8 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF4746 PF15928.5 CRK12444.1 - 0.21 11.0 10.1 0.29 10.5 10.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CDC45 PF02724.14 CRK12444.1 - 0.26 9.6 16.2 0.32 9.2 16.2 1.1 1 0 0 1 1 1 0 CDC45-like protein SpoIIP PF07454.11 CRK12444.1 - 0.52 9.7 8.7 0.7 9.3 8.7 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Zip PF02535.22 CRK12444.1 - 0.53 9.5 2.3 0.61 9.2 2.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter RR_TM4-6 PF06459.12 CRK12444.1 - 0.62 9.8 14.3 0.86 9.4 14.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Casc1_N PF15927.5 CRK12444.1 - 0.66 9.6 18.9 0.96 9.1 18.9 1.2 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus Hid1 PF12722.7 CRK12444.1 - 0.69 8.0 7.0 0.83 7.7 7.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SLC12 PF03522.15 CRK12444.1 - 0.77 8.7 7.8 1 8.3 7.8 1.1 1 0 0 1 1 1 0 Solute carrier family 12 GREB1 PF15782.5 CRK12444.1 - 0.81 6.7 5.9 0.89 6.6 5.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Ycf1 PF05758.12 CRK12444.1 - 0.94 7.3 10.1 1.2 7.0 10.1 1.0 1 0 0 1 1 1 0 Ycf1 Sporozoite_P67 PF05642.11 CRK12444.1 - 1.1 7.2 8.4 1.5 6.8 8.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SID-1_RNA_chan PF13965.6 CRK12444.1 - 1.2 7.5 2.4 1.5 7.1 2.4 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Slu7 PF11708.8 CRK12444.1 - 1.7 8.4 19.1 2.5 7.8 19.1 1.2 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor DUF913 PF06025.12 CRK12444.1 - 1.9 7.4 4.8 2.4 7.0 4.8 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) NPR3 PF03666.13 CRK12444.1 - 2.3 6.9 12.7 2.8 6.6 12.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CPSF100_C PF13299.6 CRK12444.1 - 2.3 8.4 9.9 3.9 7.6 9.9 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Afi1 PF07792.12 CRK12444.1 - 2.4 8.7 14.4 4.1 7.9 14.4 1.3 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking MCM_bind PF09739.9 CRK12444.1 - 3.4 6.0 10.3 4.4 5.6 10.3 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Connexin PF00029.19 CRK12444.1 - 3.7 7.2 9.4 1.6 8.4 6.9 1.6 2 0 0 2 2 2 0 Connexin Peptidase_S64 PF08192.11 CRK12444.1 - 4.9 5.5 8.3 6.1 5.2 8.3 1.1 1 0 0 1 1 1 0 Peptidase family S64 ALMT PF11744.8 CRK12444.1 - 5.6 5.7 5.8 6.8 5.4 5.8 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter SAPS PF04499.15 CRK12444.1 - 5.6 5.6 10.3 6.7 5.4 10.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Iron_permease PF04120.12 CRK12444.1 - 6 6.6 5.1 11 5.8 5.1 1.4 1 0 0 1 1 1 0 Low affinity iron permease DUF1168 PF06658.12 CRK12444.1 - 6.3 6.6 28.2 11 5.8 28.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Presenilin PF01080.17 CRK12444.1 - 7 5.3 11.7 8.6 5.0 11.7 1.1 1 0 0 1 1 1 0 Presenilin TRAP_alpha PF03896.16 CRK12444.1 - 7.1 5.8 10.2 10 5.2 10.2 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CLN3 PF02487.17 CRK12444.1 - 8 5.4 4.7 10 5.0 4.7 1.1 1 0 0 1 1 1 0 CLN3 protein Rtt106 PF08512.12 CRK12445.1 - 2.8e-30 104.6 0.0 7.5e-30 103.2 0.0 1.7 2 0 0 2 2 2 1 Histone chaperone Rttp106-like PH_18 PF18469.1 CRK12445.1 - 0.0061 16.5 0.0 0.046 13.7 0.0 2.3 2 1 0 2 2 2 1 Pleckstrin homology domain bPH_2 PF03703.14 CRK12445.1 - 0.044 14.0 0.0 0.086 13.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial PH domain NOA36 PF06524.12 CRK12445.1 - 0.31 10.3 13.0 0.45 9.8 13.0 1.2 1 0 0 1 1 1 0 NOA36 protein PKD PF00801.20 CRK12446.1 - 0.017 15.0 0.1 0.061 13.2 0.1 2.0 1 0 0 1 1 1 0 PKD domain DUF5110 PF17137.4 CRK12446.1 - 0.13 12.6 0.0 0.3 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5110) MFS_1 PF07690.16 CRK12448.1 - 1.1e-40 139.6 30.1 2.2e-40 138.7 29.4 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK12448.1 - 2.7e-10 39.7 21.0 4.3e-10 39.0 21.0 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.20 CRK12448.1 - 0.069 11.4 4.7 0.047 12.0 1.6 2.0 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Lipase_GDSL_2 PF13472.6 CRK12449.1 - 2.3e-08 34.6 0.3 3.5e-08 34.1 0.3 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 CRK12449.1 - 8.5e-05 22.6 0.0 0.00011 22.2 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Sugar_tr PF00083.24 CRK12450.1 - 2.1e-67 227.9 25.8 2.5e-67 227.7 25.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK12450.1 - 4.2e-09 35.8 44.8 5.2e-08 32.2 26.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 CRK12450.1 - 6.4e-08 31.6 12.2 8.4e-05 21.3 3.8 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 CRK12450.1 - 0.0031 16.4 6.1 0.0031 16.4 6.1 2.2 2 0 0 2 2 2 1 MFS_1 like family ECH_1 PF00378.20 CRK12452.1 - 6.2e-74 248.5 0.1 7.1e-74 248.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CRK12452.1 - 6.6e-35 121.2 0.4 3.4e-34 118.8 0.4 1.8 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase SH3_9 PF14604.6 CRK12454.1 - 6.1e-06 26.0 0.0 1.5e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain zf-C3HC4 PF00097.25 CRK12454.1 - 3e-05 23.8 1.3 3e-05 23.8 1.3 5.2 6 2 0 6 6 6 1 Zinc finger, C3HC4 type (RING finger) SH3_1 PF00018.28 CRK12454.1 - 3.6e-05 23.3 0.0 7.2e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain zf-RING_UBOX PF13445.6 CRK12454.1 - 9.8e-05 22.3 1.5 9.8e-05 22.3 1.5 4.6 6 0 0 6 6 6 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CRK12454.1 - 0.00015 21.5 0.9 0.00015 21.5 0.9 5.4 5 2 1 6 6 6 1 Zinc finger, C3HC4 type (RING finger) Phage_sheath_1C PF17482.2 CRK12454.1 - 0.0014 18.5 1.2 1.9 8.5 0.1 2.3 2 0 0 2 2 2 2 Phage tail sheath C-terminal domain zf-RING_2 PF13639.6 CRK12454.1 - 0.0033 17.7 2.1 0.0033 17.7 2.1 5.5 5 0 0 5 5 5 1 Ring finger domain zf-RING_5 PF14634.6 CRK12454.1 - 0.023 14.6 0.9 0.023 14.6 0.9 5.8 6 1 1 7 7 7 0 zinc-RING finger domain zf-RING_6 PF14835.6 CRK12454.1 - 0.065 13.1 0.2 0.065 13.1 0.2 3.5 3 0 0 3 3 3 0 zf-RING of BARD1-type protein Spore_Cse60 PF10957.8 CRK12454.1 - 0.31 11.1 3.4 16 5.6 0.3 2.5 2 0 0 2 2 2 0 Sporulation protein Cse60 Chlorosome_CsmC PF11098.8 CRK12456.1 - 0.00051 20.0 2.3 0.96 9.4 0.2 2.6 2 0 0 2 2 2 2 Chlorosome envelope protein C SseC PF04888.12 CRK12456.1 - 0.065 12.8 0.1 12 5.3 0.0 2.4 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family Thionin PF00321.17 CRK12456.1 - 0.42 11.1 2.9 30 5.2 0.2 2.8 2 0 0 2 2 2 0 Plant thionin PALP PF00291.25 CRK12457.1 - 5.8e-14 52.2 0.0 6.7e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PALP PF00291.25 CRK12458.1 - 4.3e-65 220.0 0.3 5.1e-65 219.8 0.3 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme RhoGAP-FF1 PF16512.5 CRK12459.1 - 0.0056 17.3 0.0 0.012 16.2 0.0 1.5 1 0 0 1 1 1 1 p190-A and -B Rho GAPs FF domain Utp21 PF04192.12 CRK12459.1 - 0.099 12.1 0.1 0.14 11.7 0.1 1.2 1 0 0 1 1 1 0 Utp21 specific WD40 associated putative domain Ribosomal_L19 PF01245.20 CRK12460.1 - 0.0031 17.4 0.0 0.0061 16.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L19 TrkH PF02386.16 CRK12461.1 - 1.9e-142 475.2 6.0 2.7e-142 474.8 6.0 1.0 1 0 0 1 1 1 1 Cation transport protein TrkH PF02386.16 CRK12462.1 - 7.3e-142 473.3 5.9 7.3e-142 473.3 5.9 2.1 2 0 0 2 2 2 2 Cation transport protein ERCC3_RAD25_C PF16203.5 CRK12463.1 - 3.7e-120 399.7 0.4 6e-120 399.0 0.4 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 CRK12463.1 - 3.6e-33 114.4 0.0 1.7e-32 112.2 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CRK12463.1 - 2.4e-16 60.2 0.0 4.6e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CRK12463.1 - 1.9e-12 47.5 0.1 4.4e-12 46.3 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 CRK12463.1 - 2.7e-08 32.9 0.0 3.7e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain SIN1 PF05422.12 CRK12463.1 - 0.0048 17.5 1.6 0.14 12.7 0.6 2.8 2 1 0 2 2 2 1 Stress-activated map kinase interacting protein 1 (SIN1) AAA_34 PF13872.6 CRK12463.1 - 0.041 12.8 0.1 0.07 12.0 0.1 1.3 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 zf-CHY PF05495.12 CRK12464.1 - 1.3e-12 48.0 19.5 1.3e-12 48.0 19.5 1.7 2 0 0 2 2 2 1 CHY zinc finger zf-RRPl_C4 PF17026.5 CRK12464.1 - 0.011 15.8 1.5 0.011 15.8 1.5 2.1 1 1 1 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type zinc_ribbon_9 PF14369.6 CRK12464.1 - 0.22 11.8 9.6 0.44 10.9 6.7 2.5 1 1 1 2 2 2 0 zinc-ribbon HypA PF01155.19 CRK12464.1 - 3.2 7.8 13.0 3.8 7.6 10.1 2.0 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Proteasome PF00227.26 CRK12465.1 - 9.4e-55 185.1 0.1 1.4e-54 184.5 0.1 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CRK12465.1 - 1.2e-11 44.0 0.4 3.6e-11 42.5 0.1 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Zn_clus PF00172.18 CRK12466.1 - 2.8e-06 27.3 13.3 5.1e-06 26.5 13.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PSI_integrin PF17205.3 CRK12466.1 - 0.74 9.6 6.1 0.082 12.7 0.9 2.1 2 0 0 2 2 2 0 Integrin plexin domain RCC1 PF00415.18 CRK12469.1 - 1.4e-58 195.3 12.0 6.9e-11 42.6 0.1 7.6 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CRK12469.1 - 1.7e-37 126.4 30.9 9.7e-08 31.6 1.3 7.1 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat sCache_3_2 PF17203.4 CRK12469.1 - 0.13 12.4 0.0 0.33 11.1 0.0 1.6 1 0 0 1 1 1 0 Single cache domain 3 CH PF00307.31 CRK12470.1 - 4.5e-23 81.5 0.3 3.6e-21 75.4 0.1 2.3 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 CRK12470.1 - 0.023 14.5 0.0 0.043 13.7 0.0 1.5 1 0 0 1 1 1 0 CAMSAP CH domain NUDE_C PF04880.13 CRK12470.1 - 8.5 6.8 12.0 15 6.0 12.0 1.3 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region VPS9 PF02204.18 CRK12471.1 - 2e-26 92.2 0.0 3.7e-26 91.4 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CH PF00307.31 CRK12472.1 - 1.7e-25 89.3 0.0 7.4e-22 77.6 0.0 2.9 3 0 0 3 3 3 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 CRK12472.1 - 1.1e-21 76.6 0.0 3.9e-21 74.9 0.0 2.0 1 0 0 1 1 1 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.8 CRK12472.1 - 8.7e-07 28.7 0.1 2.7e-06 27.1 0.1 1.9 1 0 0 1 1 1 1 CAMSAP CH domain Fib_alpha PF08702.10 CRK12472.1 - 4.8e-05 23.6 2.9 0.51 10.5 0.1 3.9 4 0 0 4 4 4 2 Fibrinogen alpha/beta chain family EF-hand_6 PF13405.6 CRK12472.1 - 0.00069 19.3 0.3 0.0062 16.4 0.1 2.9 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 CRK12472.1 - 0.0028 18.1 2.7 0.013 15.9 2.7 2.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 CRK12472.1 - 0.0035 17.1 0.4 0.04 13.8 0.1 2.7 2 1 1 3 3 3 1 EF-hand domain pair Spectrin PF00435.21 CRK12472.1 - 0.008 16.6 16.0 1.2 9.6 2.7 4.0 4 0 0 4 4 4 2 Spectrin repeat EF-hand_1 PF00036.32 CRK12472.1 - 0.06 12.9 0.3 0.55 9.9 0.0 2.6 2 0 0 2 2 2 0 EF hand TolA_bind_tri PF16331.5 CRK12472.1 - 0.093 12.8 6.1 13 6.0 0.0 4.2 4 0 0 4 4 4 0 TolA binding protein trimerisation B1 PF02246.15 CRK12472.1 - 0.19 11.8 1.9 23 5.1 0.1 2.7 2 0 0 2 2 2 0 Protein L b1 domain Frataxin_Cyay PF01491.16 CRK12472.1 - 0.24 11.5 1.0 47 4.1 0.0 3.3 4 0 0 4 4 4 0 Frataxin-like domain Baculo_PEP_C PF04513.12 CRK12472.1 - 0.56 10.2 5.4 15 5.7 0.2 3.3 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus SF-assemblin PF06705.11 CRK12472.1 - 0.96 8.7 5.5 8.9 5.6 1.4 2.8 2 0 0 2 2 2 0 SF-assemblin/beta giardin DUF4508 PF14969.6 CRK12472.1 - 2.8 8.3 6.8 31 4.9 0.4 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4508) DUF4298 PF14131.6 CRK12472.1 - 4.2 7.4 7.8 22 5.1 0.3 3.5 5 0 0 5 5 3 0 Domain of unknown function (DUF4298) VPS9 PF02204.18 CRK12475.1 - 3e-26 91.6 0.0 5.6e-26 90.8 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Lipase_3 PF01764.25 CRK12476.1 - 4.5e-06 26.6 0.0 1.1e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) UPF0227 PF05728.12 CRK12476.1 - 0.015 15.2 0.0 0.025 14.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Hydrolase_4 PF12146.8 CRK12476.1 - 0.016 14.5 0.0 0.026 13.8 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CRK12476.1 - 0.067 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold E_Pc_C PF06752.12 CRK12476.1 - 2.4 8.2 7.3 4 7.5 7.3 1.4 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus YL1 PF05764.13 CRK12478.1 - 2.2e-109 365.3 67.2 1.5e-70 238.1 20.8 4.3 4 0 0 4 4 4 3 YL1 nuclear protein YL1_C PF08265.11 CRK12478.1 - 5.2e-14 51.7 0.5 9.9e-14 50.8 0.5 1.5 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain AAA_23 PF13476.6 CRK12478.1 - 1.3 9.5 14.3 0.54 10.7 4.8 2.5 2 0 0 2 2 2 0 AAA domain MctB PF11382.8 CRK12478.1 - 6.8 6.3 20.2 0.71 9.5 6.5 3.0 3 0 0 3 3 3 0 Copper transport outer membrane protein, MctB FA_hydroxylase PF04116.13 CRK12480.1 - 7e-22 78.2 12.1 7e-22 78.2 12.1 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily TCTP PF00838.17 CRK12481.1 - 9.5e-69 231.0 1.4 1.1e-68 230.8 1.4 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein AIM3 PF17096.5 CRK12482.1 - 0.00069 20.5 0.1 0.00069 20.5 0.1 4.3 3 2 0 3 3 3 1 Altered inheritance of mitochondria protein 3 Mis12 PF05859.12 CRK12483.1 - 3.3e-37 127.6 0.0 5e-37 127.0 0.0 1.3 1 0 0 1 1 1 1 Mis12 protein Tmemb_14 PF03647.13 CRK12483.1 - 9.8e-21 74.3 5.9 9.8e-21 74.3 5.9 2.0 2 0 0 2 2 2 1 Transmembrane proteins 14C SUIM_assoc PF16619.5 CRK12483.1 - 0.099 12.7 4.3 0.22 11.6 4.3 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 APH PF01636.23 CRK12484.1 - 3.3e-13 50.1 0.1 4.9e-13 49.6 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 CRK12484.1 - 0.0056 16.3 0.0 0.0093 15.6 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 CRK12484.1 - 0.045 13.3 0.0 0.063 12.9 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase EcKinase PF02958.20 CRK12484.1 - 0.069 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase YtxH PF12732.7 CRK12485.1 - 0.0053 17.3 0.6 0.0066 17.0 0.6 1.2 1 0 0 1 1 1 1 YtxH-like protein Syntaxin PF00804.25 CRK12485.1 - 0.011 15.4 0.1 0.014 15.0 0.1 1.1 1 0 0 1 1 1 0 Syntaxin Rab5-bind PF09311.11 CRK12485.1 - 0.012 15.0 0.6 0.013 14.9 0.6 1.0 1 0 0 1 1 1 0 Rabaptin-like protein DUF16 PF01519.16 CRK12485.1 - 0.013 16.0 0.4 0.016 15.7 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF16 Occludin_ELL PF07303.13 CRK12485.1 - 0.018 15.8 0.5 0.08 13.7 0.4 1.8 1 1 0 1 1 1 0 Occludin homology domain DUF948 PF06103.11 CRK12485.1 - 0.021 15.1 0.1 0.024 14.9 0.1 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) FlaC_arch PF05377.11 CRK12485.1 - 0.029 14.7 0.8 0.048 14.1 0.6 1.6 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.12 CRK12485.1 - 0.031 14.3 0.2 0.043 13.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 CRK12485.1 - 0.032 14.3 0.1 0.038 14.0 0.1 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Drf_FH3 PF06367.16 CRK12485.1 - 0.034 13.7 3.0 0.035 13.7 3.0 1.0 1 0 0 1 1 1 0 Diaphanous FH3 Domain LPP PF04728.13 CRK12485.1 - 0.075 13.4 0.1 0.12 12.8 0.1 1.4 1 1 0 1 1 1 0 Lipoprotein leucine-zipper Fib_alpha PF08702.10 CRK12485.1 - 0.1 12.8 0.4 0.12 12.6 0.4 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Tweety PF04906.13 CRK12485.1 - 0.12 11.0 0.1 0.14 10.7 0.1 1.0 1 0 0 1 1 1 0 Tweety ApoO PF09769.9 CRK12485.1 - 0.2 11.6 0.1 3.7 7.5 0.1 1.9 1 1 1 2 2 2 0 Apolipoprotein O DUF3552 PF12072.8 CRK12485.1 - 0.2 11.1 1.0 0.21 11.0 1.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Sterol-sensing PF12349.8 CRK12487.1 - 5.2e-31 107.6 8.9 8.6e-31 106.8 8.9 1.3 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 CRK12487.1 - 1.3e-10 40.0 3.4 1.7e-10 39.7 3.4 1.1 1 0 0 1 1 1 1 Patched family FTA2 PF13095.6 CRK12489.1 - 1.3e-07 31.5 0.0 3.7e-07 30.0 0.0 1.7 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Cyt-b5 PF00173.28 CRK12526.1 - 1.4e-17 63.5 0.2 1.5e-17 63.4 0.2 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CAP_GLY PF01302.25 CRK12527.1 - 3.7e-12 46.1 0.3 6e-12 45.4 0.3 1.3 1 0 0 1 1 1 1 CAP-Gly domain Condensation PF00668.20 CRK12528.1 - 4.7e-67 226.6 0.0 6.7e-67 226.1 0.0 1.1 1 0 0 1 1 1 1 Condensation domain ketoacyl-synt PF00109.26 CRK12528.1 - 1.6e-55 188.5 0.0 2.9e-55 187.6 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 CRK12528.1 - 2.2e-39 135.5 0.0 3.9e-39 134.7 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase AMP-binding PF00501.28 CRK12528.1 - 6e-34 117.4 0.1 9.7e-34 116.7 0.1 1.3 1 0 0 1 1 1 1 AMP-binding enzyme KR PF08659.10 CRK12528.1 - 2.5e-27 96.0 0.4 1.5e-23 83.6 0.0 2.5 1 1 1 2 2 2 2 KR domain Ketoacyl-synt_C PF02801.22 CRK12528.1 - 9.3e-27 93.4 1.7 7.3e-26 90.5 0.1 2.7 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 CRK12528.1 - 6.3e-19 68.6 0.0 1.1e-12 48.1 0.0 2.4 1 1 1 2 2 2 2 Acyl transferase domain KAsynt_C_assoc PF16197.5 CRK12528.1 - 4.6e-13 49.6 0.0 1.4e-12 48.1 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 CRK12528.1 - 5.8e-05 22.6 0.0 0.00012 21.6 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain PP-binding PF00550.25 CRK12528.1 - 0.00039 20.7 1.3 0.0013 19.1 0.4 2.4 2 0 0 2 2 2 1 Phosphopantetheine attachment site NAD_binding_4 PF07993.12 CRK12529.1 - 2.7e-31 108.7 0.0 3e-30 105.3 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 CRK12529.1 - 1.1e-29 103.3 0.0 1.6e-29 102.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 CRK12529.1 - 2.2e-10 40.7 0.1 5.8e-10 39.4 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 CRK12529.1 - 7.2e-07 28.9 0.0 1.2e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CRK12529.1 - 0.0033 16.5 0.0 0.0051 15.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 CRK12529.1 - 0.034 14.0 0.1 0.24 11.3 0.0 2.3 2 0 0 2 2 2 0 NAD(P)H-binding dTDP_sugar_isom PF00908.17 CRK12529.1 - 0.18 11.5 0.0 0.33 10.6 0.0 1.3 1 0 0 1 1 1 0 dTDP-4-dehydrorhamnose 3,5-epimerase CFEM PF05730.11 CRK12530.1 - 4.9e-11 42.6 12.4 7.8e-11 41.9 12.4 1.3 1 0 0 1 1 1 1 CFEM domain adh_short PF00106.25 CRK12532.1 - 5.4e-21 75.0 0.1 1.2e-19 70.5 0.1 2.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK12532.1 - 4.4e-17 62.4 0.1 5.9e-16 58.7 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK12532.1 - 8e-06 25.9 0.6 2.3e-05 24.4 0.6 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 CRK12532.1 - 0.0017 17.9 0.5 0.013 15.0 0.5 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Mpv17_PMP22 PF04117.12 CRK12533.1 - 2.9e-18 65.9 0.4 1.4e-17 63.6 0.2 2.2 2 0 0 2 2 2 1 Mpv17 / PMP22 family DHO_dh PF01180.21 CRK12534.1 - 6.3e-69 232.4 0.0 7.2e-56 189.6 0.0 2.2 1 1 1 2 2 2 2 Dihydroorotate dehydrogenase PcrB PF01884.17 CRK12534.1 - 0.0091 15.5 1.5 0.11 12.0 0.1 2.2 2 0 0 2 2 2 1 PcrB family PEP_hydrolase PF09370.10 CRK12534.1 - 0.01 15.1 0.2 0.022 14.0 0.1 1.7 2 0 0 2 2 2 0 Phosphoenolpyruvate hydrolase-like adh_short PF00106.25 CRK12535.1 - 1.2e-10 41.2 1.0 7.4e-10 38.6 1.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK12535.1 - 4.9e-09 36.1 2.0 3.3e-08 33.4 2.0 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase PUD1_2 PF18457.1 CRK12535.1 - 0.089 12.8 0.1 0.13 12.3 0.1 1.2 1 0 0 1 1 1 0 Up-Regulated in long-lived daf-2 HET PF06985.11 CRK12537.1 - 6.2e-32 111.0 0.1 1.2e-31 110.1 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Peptidase_M3 PF01432.20 CRK12539.1 - 1e-150 503.0 0.0 1.6e-150 502.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M3 BIR PF00653.21 CRK12539.1 - 7.7e-44 148.2 4.4 1.3e-21 77.0 0.1 2.6 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain EF-hand_9 PF14658.6 CRK12539.1 - 1.7e-10 41.1 0.0 5.9e-05 23.3 0.0 3.5 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 CRK12539.1 - 1.3e-06 28.7 9.2 2.4e-05 24.7 0.0 3.7 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.6 CRK12539.1 - 6.6e-06 25.6 0.4 0.15 12.0 0.0 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 CRK12539.1 - 2.4e-05 23.6 0.1 0.38 10.4 0.0 3.2 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 CRK12539.1 - 7.2e-05 22.5 0.3 0.0081 16.0 0.0 4.2 5 0 0 5 5 5 1 EF-hand domain pair Peptidase_M2 PF01401.18 CRK12539.1 - 0.099 11.2 7.4 1.5 7.3 0.0 3.0 3 0 0 3 3 3 0 Angiotensin-converting enzyme Biotin_carb_N PF00289.22 CRK12539.1 - 0.11 13.0 0.0 0.35 11.4 0.0 1.8 1 0 0 1 1 1 0 Biotin carboxylase, N-terminal domain Methyltransf_25 PF13649.6 CRK12540.1 - 4e-13 49.9 0.0 7.1e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CRK12540.1 - 1.6e-12 47.9 0.0 3e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK12540.1 - 6.5e-06 26.8 0.0 1.4e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK12540.1 - 1.3e-05 25.1 0.0 1.7e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CRK12540.1 - 1.7e-05 24.7 0.0 2.6e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 CRK12540.1 - 0.001 18.2 0.0 0.0015 17.7 0.0 1.1 1 0 0 1 1 1 1 DREV methyltransferase MTS PF05175.14 CRK12540.1 - 0.0016 18.0 0.0 0.0025 17.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain tRNA_U5-meth_tr PF05958.11 CRK12540.1 - 0.03 13.3 0.0 0.042 12.8 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_32 PF13679.6 CRK12540.1 - 0.048 13.7 0.0 0.072 13.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 CRK12540.1 - 0.064 12.3 0.0 0.095 11.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Gpr1_Fun34_YaaH PF01184.19 CRK12541.1 - 6.4e-28 97.8 17.5 1.1e-27 97.0 17.5 1.4 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family CoA_binding_2 PF13380.6 CRK12541.1 - 4.2e-27 94.9 0.2 8.7e-27 93.9 0.2 1.4 1 0 0 1 1 1 1 CoA binding domain DUF853 PF05872.12 CRK12541.1 - 0.26 9.8 0.4 0.43 9.1 0.0 1.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) Cu_bind_like PF02298.17 CRK12543.1 - 0.0019 18.2 3.5 0.54 10.3 0.2 3.1 2 2 0 2 2 2 2 Plastocyanin-like domain Cupredoxin_1 PF13473.6 CRK12543.1 - 0.013 15.6 0.8 3.7 7.7 0.0 3.2 3 0 0 3 3 3 0 Cupredoxin-like domain Cas_csx3 PF09620.10 CRK12543.1 - 0.13 12.1 0.0 5.8 6.9 0.0 2.7 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_csx3) RBD-FIP PF09457.10 CRK12543.1 - 0.21 11.5 0.4 0.43 10.5 0.4 1.4 1 0 0 1 1 1 0 FIP domain SUR7 PF06687.12 CRK12544.1 - 2e-26 93.0 6.8 2.4e-26 92.7 6.8 1.1 1 0 0 1 1 1 1 SUR7/PalI family Wzy_C PF04932.15 CRK12544.1 - 0.017 14.7 0.0 1.2 8.7 0.0 2.3 2 0 0 2 2 2 0 O-Antigen ligase DUF4231 PF14015.6 CRK12544.1 - 0.033 14.7 5.5 0.43 11.1 0.8 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) PMP22_Claudin PF00822.20 CRK12544.1 - 0.034 14.0 4.7 0.087 12.7 1.6 2.1 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family DUF1003 PF06210.11 CRK12544.1 - 0.1 12.7 0.8 0.68 10.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1003) DUF1218 PF06749.12 CRK12544.1 - 0.18 12.3 0.1 0.18 12.3 0.1 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1218) SLATT_5 PF18160.1 CRK12544.1 - 9.3 5.5 8.3 1.1 8.5 1.4 2.1 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 FAD_binding_2 PF00890.24 CRK12545.1 - 1.1e-32 113.7 2.2 4.5e-25 88.6 0.0 2.0 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 CRK12545.1 - 1.8e-08 34.2 1.4 1e-06 28.4 0.0 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 CRK12545.1 - 3.5e-06 26.5 1.0 0.016 14.5 0.1 2.6 3 0 0 3 3 3 2 FAD binding domain Pyr_redox_2 PF07992.14 CRK12545.1 - 2.6e-05 23.6 1.0 0.00061 19.1 1.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CRK12545.1 - 7.4e-05 21.6 4.7 0.0067 15.2 0.1 3.2 3 0 0 3 3 3 2 HI0933-like protein DAO PF01266.24 CRK12545.1 - 0.0052 16.4 3.4 0.0052 16.4 3.4 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 CRK12545.1 - 0.0061 15.7 0.2 0.0061 15.7 0.2 2.2 3 0 0 3 3 3 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 CRK12545.1 - 0.028 13.5 0.6 0.33 10.0 0.1 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 CRK12545.1 - 0.03 13.6 0.1 2.4 7.3 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CRK12545.1 - 0.089 13.0 0.9 0.31 11.3 0.4 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CRK12545.1 - 0.18 11.1 0.1 0.31 10.3 0.1 1.3 1 0 0 1 1 1 0 Thi4 family DSPc PF00782.20 CRK12547.1 - 9.9e-08 31.9 0.0 1.9e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain UPF0121 PF03661.13 CRK12547.1 - 0.0034 16.8 0.9 0.005 16.3 0.9 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) Y_phosphatase PF00102.27 CRK12547.1 - 0.004 16.8 0.1 0.006 16.2 0.1 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 CRK12547.1 - 0.15 12.0 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family SNF PF00209.18 CRK12548.1 - 1.4e-22 80.1 5.7 1.4e-22 80.1 5.7 1.8 2 0 0 2 2 2 1 Sodium:neurotransmitter symporter family Bac_rhamnosid_C PF17390.2 CRK12549.1 - 0.00012 21.8 0.0 0.00038 20.2 0.0 1.8 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase C-terminal domain Bac_rhamnosid6H PF17389.2 CRK12549.1 - 0.00048 19.5 0.1 0.00078 18.8 0.1 1.2 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Trehalase PF01204.18 CRK12549.1 - 0.001 18.0 0.3 0.0015 17.5 0.3 1.1 1 0 0 1 1 1 1 Trehalase SNF PF00209.18 CRK12550.1 - 3.4e-76 257.0 35.3 1.6e-49 169.0 17.0 2.5 3 0 0 3 3 3 2 Sodium:neurotransmitter symporter family Sporozoite_P67 PF05642.11 CRK12552.1 - 8.5 4.3 6.0 9.9 4.1 6.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Corona_S2 PF01601.16 CRK12553.1 - 0.15 10.6 0.4 0.22 10.0 0.4 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein DUF2207 PF09972.9 CRK12553.1 - 5.8 5.6 4.8 9.1 4.9 4.5 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) RNA_pol PF00940.19 CRK12554.1 - 1.8e-185 616.7 0.0 2.4e-185 616.3 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 CRK12554.1 - 8.9e-66 222.6 0.2 8.9e-66 222.6 0.2 1.9 2 0 0 2 2 2 1 DNA-directed RNA polymerase N-terminal SNF PF00209.18 CRK12554.1 - 1.8e-58 198.5 16.9 1.3e-30 106.6 4.0 2.2 2 0 0 2 2 2 2 Sodium:neurotransmitter symporter family E1-N PF14463.6 CRK12554.1 - 0.042 13.7 1.1 0.14 12.0 1.1 1.9 1 0 0 1 1 1 0 E1 N-terminal domain Corona_S2 PF01601.16 CRK12556.1 - 0.023 13.2 0.8 0.027 13.0 0.8 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Herpes_LMP1 PF05297.11 CRK12556.1 - 0.17 11.1 5.3 0.2 10.8 5.3 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF2157 PF09925.9 CRK12556.1 - 0.21 11.4 8.7 0.027 14.3 2.8 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2157) DUF3188 PF11384.8 CRK12556.1 - 0.38 10.5 3.0 5.1 6.9 0.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) DUF3810 PF12725.7 CRK12556.1 - 6.6 6.0 6.2 5.2 6.3 5.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) RNA_pol PF00940.19 CRK12557.1 - 1.7e-185 616.7 0.0 2.3e-185 616.3 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 CRK12557.1 - 1.9e-103 346.4 0.6 1.9e-103 346.4 0.6 1.9 2 0 0 2 2 2 1 DNA-directed RNA polymerase N-terminal E1-N PF14463.6 CRK12557.1 - 0.043 13.6 2.3 0.066 13.0 0.8 2.1 2 0 0 2 2 2 0 E1 N-terminal domain RsfS PF02410.15 CRK12558.1 - 2.1e-11 44.1 0.0 5.9e-11 42.7 0.0 1.8 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation Importin_rep_5 PF18816.1 CRK12558.1 - 0.16 12.3 0.1 0.43 10.9 0.1 1.8 1 0 0 1 1 1 0 Importin repeat DHHA2 PF02833.14 CRK12559.1 - 1.3e-34 119.4 0.0 1.5e-34 119.3 0.0 1.0 1 0 0 1 1 1 1 DHHA2 domain DUF2156 PF09924.9 CRK12559.1 - 0.023 13.7 0.1 0.034 13.2 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2156) GATase PF00117.28 CRK12561.1 - 4.7e-12 46.1 0.0 6.6e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GPR_Gpa2_C PF11970.8 CRK12563.1 - 6.5e-21 74.2 0.1 1.3e-20 73.3 0.1 1.5 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term MAP65_ASE1 PF03999.12 CRK12563.1 - 6.8 5.3 6.1 8.4 5.0 6.1 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) RsfS PF02410.15 CRK12565.1 - 5.3e-12 46.0 0.0 1.9e-11 44.2 0.0 2.0 2 0 0 2 2 2 1 Ribosomal silencing factor during starvation DHHA2 PF02833.14 CRK12567.1 - 6.9e-38 130.0 0.0 1e-37 129.5 0.0 1.2 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 CRK12567.1 - 1.3e-19 70.3 0.0 7.4e-09 35.8 0.0 2.7 2 1 1 3 3 3 2 DHH family LpxK PF02606.14 CRK12567.1 - 0.00064 18.9 0.0 0.28 10.2 0.0 2.3 2 0 0 2 2 2 2 Tetraacyldisaccharide-1-P 4'-kinase Prot_ATP_ID_OB PF16450.5 CRK12567.1 - 0.0099 15.8 1.1 2.2 8.3 0.1 2.8 2 0 0 2 2 2 2 Proteasomal ATPase OB C-terminal domain GATase PF00117.28 CRK12569.1 - 3e-12 46.7 0.0 4.2e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Git3 PF11710.8 CRK12570.1 - 9.3e-59 198.6 19.2 1.7e-58 197.7 19.2 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 CRK12570.1 - 1e-20 73.6 0.1 1e-20 73.6 0.1 3.1 3 0 0 3 3 3 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.21 CRK12570.1 - 1e-07 31.6 0.0 1.6e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_2 PF00002.24 CRK12570.1 - 0.00065 19.1 6.9 0.0012 18.2 6.9 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) DUF4834 PF16118.5 CRK12570.1 - 0.0008 20.3 0.5 4.3 8.4 2.3 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF4834) SUIM_assoc PF16619.5 CRK12570.1 - 0.0041 17.2 4.6 0.016 15.3 4.6 2.0 1 1 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 MAP65_ASE1 PF03999.12 CRK12570.1 - 0.0054 15.5 3.1 0.0054 15.5 3.1 1.4 2 0 0 2 2 2 1 Microtubule associated protein (MAP65/ASE1 family) MAD PF05557.13 CRK12572.1 - 3.7e-49 167.7 65.1 2.1e-46 158.6 7.8 3.1 1 1 1 2 2 2 2 Mitotic checkpoint protein Tam41_Mmp37 PF09139.11 CRK12574.1 - 1.5e-105 353.2 0.0 2e-105 352.8 0.0 1.1 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial tRNA_bind PF01588.20 CRK12576.1 - 4.5e-22 78.0 0.1 1e-21 76.8 0.1 1.7 1 1 0 1 1 1 1 Putative tRNA binding domain GST_C_2 PF13410.6 CRK12576.1 - 3.6e-05 23.7 0.0 6.8e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CRK12576.1 - 0.00014 22.0 0.8 0.0015 18.7 0.0 2.5 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CRK12576.1 - 0.047 13.9 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain SNF2_N PF00176.23 CRK12578.1 - 3.7e-61 206.8 0.1 6.8e-61 205.9 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CRK12578.1 - 9.1e-23 80.7 0.0 2.2e-22 79.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 CRK12578.1 - 6.7e-06 25.5 0.0 1.5e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 CRK12578.1 - 7.2e-06 26.1 0.1 2.6e-05 24.3 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 CRK12578.1 - 0.0068 15.6 0.0 0.0068 15.6 0.0 2.5 3 1 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 Glyco_hydro_16 PF00722.21 CRK12579.1 - 2.3e-12 46.8 0.0 3.2e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 CRK12579.1 - 3.4e-05 22.5 1.1 0.17 10.3 0.0 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Sld5 PF05916.11 CRK12583.1 - 3.4e-30 104.7 0.0 5.3e-30 104.1 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein MIP PF00230.20 CRK12585.1 - 2.1e-43 148.7 15.4 2.6e-43 148.3 15.4 1.0 1 0 0 1 1 1 1 Major intrinsic protein Vut_1 PF02592.15 CRK12585.1 - 1.4 9.2 10.8 0.24 11.7 2.6 3.0 2 1 2 4 4 4 0 Putative vitamin uptake transporter NPP1 PF05630.11 CRK12587.1 - 0.012 15.7 2.2 0.016 15.3 2.2 1.4 1 0 0 1 1 1 0 Necrosis inducing protein (NPP1) Aminotran_3 PF00202.21 CRK12590.1 - 8.5e-05 21.4 0.0 0.00013 20.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III DUF805 PF05656.14 CRK12590.1 - 0.041 14.3 0.8 0.27 11.7 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF805) Sacchrp_dh_C PF16653.5 CRK12655.1 - 1.3e-36 127.1 0.1 2.6e-36 126.1 0.1 1.5 1 1 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain RNA_pol_Rpb2_2 PF04561.14 CRK12701.1 - 1.5e-08 34.5 0.0 1.9e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 AMP_N PF05195.16 CRK12714.1 - 1.5e-19 70.0 0.0 2.1e-19 69.5 0.0 1.2 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Fer2 PF00111.27 CRK12714.1 - 0.093 12.7 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Ribosomal_S8 PF00410.19 CRK12720.1 - 3.1e-11 43.3 0.0 4e-10 39.7 0.0 2.0 1 1 0 1 1 1 1 Ribosomal protein S8 SPO11_like PF03533.14 CRK12720.1 - 0.062 13.4 0.9 0.081 13.0 0.1 1.6 2 0 0 2 2 2 0 SPO11 homologue Aminotran_1_2 PF00155.21 CRK12723.1 - 2.6e-39 135.4 0.0 3.1e-39 135.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 CRK12723.1 - 5.7e-07 28.7 0.1 8e-07 28.2 0.1 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Aminotran_5 PF00266.19 CRK12723.1 - 1.6e-06 27.3 0.0 2.7e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 CRK12723.1 - 3.5e-06 25.8 0.0 5.5e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 CRK12723.1 - 0.0064 15.8 0.1 0.0092 15.3 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Shugoshin_N PF07558.11 CRK12727.1 - 0.092 12.6 0.6 0.092 12.6 0.6 2.2 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region Seryl_tRNA_N PF02403.22 CRK12727.1 - 5.1 7.4 9.7 1.6 9.0 6.2 2.0 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain NGP1NT PF08153.12 CRK12729.1 - 2.9e-76 253.9 0.8 2.5e-49 166.7 0.2 2.3 2 0 0 2 2 2 2 NGP1NT (NUC091) domain But2 PF09792.9 CRK12729.1 - 1.7e-55 187.3 0.4 1.7e-55 187.3 0.4 2.0 2 0 0 2 2 2 1 Ubiquitin 3 binding protein But2 C-terminal domain MMR_HSR1 PF01926.23 CRK12729.1 - 5.7e-17 61.8 0.0 1.3e-13 51.0 0.0 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 CRK12729.1 - 2.6e-06 27.0 0.1 7.7e-05 22.3 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CRK12729.1 - 0.00018 21.5 0.0 0.00038 20.4 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase Arf PF00025.21 CRK12729.1 - 0.017 14.6 0.1 0.51 9.8 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family NGP1NT PF08153.12 CRK12733.1 - 1.2e-49 167.8 0.2 2e-49 167.1 0.2 1.4 1 0 0 1 1 1 1 NGP1NT (NUC091) domain ABC2_membrane PF01061.24 CRK12733.1 - 3.6e-37 127.8 18.2 3.6e-37 127.8 18.2 1.8 2 0 0 2 2 2 1 ABC-2 type transporter MMR_HSR1 PF01926.23 CRK12733.1 - 4.3e-17 62.2 0.0 1.1e-13 51.3 0.0 2.7 2 1 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 CRK12733.1 - 2.4e-06 27.2 0.1 6.3e-05 22.5 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CRK12733.1 - 0.00013 21.9 0.0 0.0003 20.7 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase ABC2_membrane_3 PF12698.7 CRK12733.1 - 0.0034 16.6 32.8 0.0045 16.1 28.0 2.1 1 1 1 2 2 2 1 ABC-2 family transporter protein Arf PF00025.21 CRK12733.1 - 0.014 14.9 0.1 0.42 10.1 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family ThrE PF06738.12 CRK12733.1 - 0.058 12.7 3.3 0.11 11.9 3.3 1.4 1 0 0 1 1 1 0 Putative threonine/serine exporter GTP_EFTU PF00009.27 CRK12733.1 - 0.066 12.7 0.0 2.6 7.6 0.0 2.7 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 CRK12733.1 - 0.16 12.4 0.0 0.35 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Dynamin_N PF00350.23 CRK12733.1 - 0.19 11.8 0.3 10 6.2 0.1 3.0 2 1 1 3 3 3 0 Dynamin family ABC2_membrane_2 PF12679.7 CRK12733.1 - 5.7 6.1 17.5 66 2.6 17.5 2.1 1 1 0 1 1 1 0 ABC-2 family transporter protein ABC2_membrane PF01061.24 CRK12737.1 - 1.4e-27 96.5 13.9 1.4e-27 96.5 13.9 3.4 2 1 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 CRK12737.1 - 6e-25 88.4 0.0 1.1e-24 87.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter MFS_1 PF07690.16 CRK12737.1 - 6.9e-13 48.2 24.5 6.9e-13 48.2 24.5 2.3 3 0 0 3 3 3 1 Major Facilitator Superfamily ABC2_membrane_3 PF12698.7 CRK12737.1 - 4.3e-05 22.8 22.6 4.3e-05 22.8 22.6 2.6 3 0 0 3 3 3 1 ABC-2 family transporter protein AAA_21 PF13304.6 CRK12737.1 - 0.00015 21.7 0.0 0.64 9.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 CRK12737.1 - 0.0075 16.8 0.0 0.014 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 CRK12737.1 - 0.011 15.5 0.0 0.029 14.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CRK12737.1 - 0.021 14.7 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_33 PF13671.6 CRK12737.1 - 0.025 14.7 0.0 0.058 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 CRK12737.1 - 0.031 13.8 0.0 0.07 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CRK12737.1 - 0.037 14.4 0.0 0.076 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 CRK12737.1 - 0.049 13.5 0.0 0.091 12.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 CRK12737.1 - 0.065 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain EGF_2 PF07974.13 CRK12737.1 - 0.16 12.4 26.8 0.19 12.1 1.5 3.8 3 0 0 3 3 3 0 EGF-like domain ABC2_membrane_2 PF12679.7 CRK12737.1 - 0.36 10.1 11.5 1.3 8.3 11.5 2.1 1 0 0 1 1 1 0 ABC-2 family transporter protein EphA2_TM PF14575.6 CRK12737.1 - 0.45 11.4 2.1 7.8 7.5 0.0 2.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Root_cap PF06830.11 CRK12737.1 - 0.65 10.2 4.2 0.28 11.3 0.8 2.2 2 0 0 2 2 2 0 Root cap DUF3435 PF11917.8 CRK12739.1 - 7.3e-22 77.9 0.0 1e-21 77.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Transposase_24 PF03004.14 CRK12739.1 - 0.047 13.8 0.4 6.9 6.8 0.0 2.2 2 0 0 2 2 2 0 Plant transposase (Ptta/En/Spm family) DUF3723 PF12520.8 CRK12741.1 - 2.9e-09 36.1 0.2 1.2e-08 34.1 0.2 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3723) NifQ PF04891.12 CRK12741.1 - 0.12 12.7 3.6 0.37 11.1 0.0 2.0 1 1 1 2 2 2 0 NifQ DUF3723 PF12520.8 CRK12743.1 - 9.5e-31 107.0 0.2 6.9e-20 71.2 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3723) Helo_like_N PF17111.5 CRK12745.1 - 1.5e-24 86.6 2.1 4.5e-19 68.7 0.1 3.2 2 1 1 3 3 3 3 Fungal N-terminal domain of STAND proteins Kelch_5 PF13854.6 CRK12745.1 - 4e-13 49.0 0.1 8.7e-11 41.6 0.0 3.6 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.6 CRK12745.1 - 1.8e-06 27.9 0.3 0.31 11.1 0.1 4.2 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.25 CRK12745.1 - 0.00034 20.1 2.2 0.14 11.8 0.1 3.8 3 0 0 3 3 3 2 Kelch motif Rootletin PF15035.6 CRK12745.1 - 0.095 12.7 0.8 0.2 11.7 0.8 1.4 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Kelch_3 PF13415.6 CRK12745.1 - 0.11 12.8 5.9 1.6 9.1 0.1 4.1 4 0 0 4 4 4 0 Galactose oxidase, central domain zf-RING_2 PF13639.6 CRK12749.1 - 0.036 14.4 7.2 0.063 13.6 7.2 1.4 1 0 0 1 1 1 0 Ring finger domain Prok-RING_1 PF14446.6 CRK12749.1 - 0.13 12.2 2.2 0.29 11.1 2.2 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Nab2p_Zf1 PF18260.1 CRK12749.1 - 4 7.4 8.7 0.2 11.6 2.2 2.1 2 0 0 2 2 2 0 Nuclear polyadenylated RNA-binding 2 protein CCCH zinc finger 1 DUF755 PF05501.11 CRK12749.1 - 9.8 6.5 6.8 0.96 9.7 0.3 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF755) DUF1996 PF09362.10 CRK12750.1 - 2.3e-16 60.6 1.1 2.7e-16 60.3 1.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) FA_desaturase PF00487.24 CRK12751.1 - 3.9e-24 85.9 16.7 1.1e-23 84.4 16.7 1.7 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 CRK12751.1 - 5.2e-07 29.9 0.0 1.3e-06 28.6 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3474) Abhydrolase_6 PF12697.7 CRK12752.1 - 6.4e-05 23.7 1.5 0.00029 21.5 0.1 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CRK12752.1 - 0.00098 18.8 0.0 0.0019 17.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 CRK12752.1 - 0.029 14.2 0.0 0.049 13.5 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase PGAP1 PF07819.13 CRK12752.1 - 0.067 12.9 0.2 0.14 11.8 0.2 1.4 1 1 0 1 1 1 0 PGAP1-like protein 7tm_2 PF00002.24 CRK12754.1 - 4.6e-08 32.6 1.3 6.1e-08 32.3 1.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 CRK12754.1 - 2.9e-07 29.9 6.0 3.9e-07 29.5 6.0 1.1 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Git3 PF11710.8 CRK12754.1 - 0.0006 19.6 5.8 0.00081 19.2 5.8 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Frizzled PF01534.17 CRK12754.1 - 0.0013 17.8 0.3 0.0017 17.4 0.3 1.1 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region STE3 PF02076.15 CRK12754.1 - 0.0074 15.5 1.1 0.01 15.1 1.1 1.2 1 0 0 1 1 1 1 Pheromone A receptor DUF1295 PF06966.12 CRK12754.1 - 0.01 15.4 0.5 0.099 12.1 0.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1295) TMEMspv1-c74-12 PF11044.8 CRK12754.1 - 0.094 12.7 0.4 0.21 11.6 0.4 1.5 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Zn_clus PF00172.18 CRK12756.1 - 2.7e-10 40.2 12.2 9.1e-10 38.5 12.2 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Clusterin PF01093.17 CRK12756.1 - 0.044 12.8 1.1 0.049 12.7 1.1 1.1 1 0 0 1 1 1 0 Clusterin zinc_ribbon_6 PF14599.6 CRK12756.1 - 0.086 12.9 4.9 0.23 11.5 3.2 2.3 2 0 0 2 2 2 0 Zinc-ribbon Chon_Sulph_att PF06566.11 CRK12756.1 - 0.1 12.5 0.8 0.16 11.9 0.6 1.4 1 1 0 1 1 1 0 Chondroitin sulphate attachment domain Endosulfine PF04667.17 CRK12757.1 - 3.4e-18 65.5 0.1 5.1e-18 65.0 0.1 1.3 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region HSP70 PF00012.20 CRK12758.1 - 3.5e-53 180.7 0.0 5.3e-53 180.1 0.0 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CRK12758.1 - 2.2e-06 26.7 0.3 2.3e-05 23.4 0.3 2.1 1 1 0 1 1 1 1 MreB/Mbl protein DDR PF08841.10 CRK12758.1 - 0.065 12.2 1.8 15 4.4 0.0 2.9 2 1 0 3 3 3 0 Diol dehydratase reactivase ATPase-like domain Rep_4 PF05797.11 CRK12758.1 - 0.16 11.1 0.0 0.36 9.9 0.0 1.5 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) Gmx_para_CXXCG PF09535.10 CRK12759.1 - 0.029 13.6 3.3 0.55 9.5 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (Gmx_para_CXXCG) zf-RING_2 PF13639.6 CRK12761.1 - 2e-10 40.8 9.2 3.1e-10 40.2 9.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 CRK12761.1 - 1e-08 34.8 3.6 1e-08 34.8 3.6 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 CRK12761.1 - 6.1e-08 32.4 8.9 9.8e-08 31.7 8.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CRK12761.1 - 5.3e-07 29.6 3.7 7.7e-07 29.0 1.9 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 CRK12761.1 - 1.2e-06 28.7 8.1 2e-06 28.0 8.1 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CRK12761.1 - 1.9e-06 27.7 7.4 3e-06 27.0 7.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CRK12761.1 - 6.9e-05 22.7 5.6 0.00012 22.0 5.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CRK12761.1 - 0.00035 20.4 8.7 0.002 17.9 7.6 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 CRK12761.1 - 0.00048 19.7 6.5 0.00094 18.8 6.5 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Baculo_IE-1 PF05290.11 CRK12761.1 - 0.00081 19.4 2.2 0.0012 18.9 2.2 1.2 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-ANAPC11 PF12861.7 CRK12761.1 - 0.0028 17.7 3.4 0.0044 17.0 3.4 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 CRK12761.1 - 0.006 16.7 4.7 0.015 15.5 4.7 1.7 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING Zf_RING PF16744.5 CRK12761.1 - 0.0068 16.5 2.7 0.0068 16.5 2.7 1.6 1 1 0 1 1 1 1 KIAA1045 RING finger Fibrillin_U_N PF18193.1 CRK12761.1 - 0.035 14.2 1.7 0.48 10.6 1.1 2.5 2 0 0 2 2 2 0 Fibrillin 1 unique N-terminal domain Protocadherin PF08374.11 CRK12761.1 - 0.089 12.8 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 Protocadherin zf-UDP PF14569.6 CRK12761.1 - 0.11 12.6 3.5 0.23 11.6 3.4 1.6 2 0 0 2 2 1 0 Zinc-binding RING-finger zf-RING_6 PF14835.6 CRK12761.1 - 0.15 11.9 2.7 0.24 11.3 2.7 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein FANCL_C PF11793.8 CRK12761.1 - 0.25 11.6 6.8 3.1 8.0 6.8 2.3 1 1 1 2 2 2 0 FANCL C-terminal domain Prok-RING_1 PF14446.6 CRK12761.1 - 0.38 10.7 5.6 11 6.0 0.1 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_4 PF14570.6 CRK12761.1 - 0.39 10.6 6.4 0.51 10.2 5.5 1.7 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain RINGv PF12906.7 CRK12761.1 - 0.53 10.5 7.9 0.95 9.6 7.9 1.4 1 0 0 1 1 1 0 RING-variant domain PHD PF00628.29 CRK12761.1 - 0.73 9.8 6.4 2.1 8.3 6.5 1.8 1 1 0 1 1 1 0 PHD-finger zf-C2HC5 PF06221.13 CRK12761.1 - 1.4 9.0 7.2 0.5 10.4 1.0 2.3 1 1 1 2 2 2 0 Putative zinc finger motif, C2HC5-type RecR PF02132.15 CRK12761.1 - 1.7 8.3 7.3 5.4 6.7 1.0 2.4 2 0 0 2 2 2 0 RecR protein DUF4091 PF13320.6 CRK12762.1 - 0.015 15.4 0.1 0.45 10.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4091) NACHT PF05729.12 CRK12764.1 - 7.9e-08 32.4 0.0 2.3e-07 30.9 0.0 1.8 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 CRK12764.1 - 0.00014 22.2 0.0 0.00043 20.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain Ank_3 PF13606.6 CRK12764.1 - 0.00048 20.4 0.0 0.093 13.3 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 CRK12764.1 - 0.00071 20.1 0.0 0.0021 18.6 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) AAA_16 PF13191.6 CRK12764.1 - 0.0011 19.4 0.0 0.021 15.2 0.0 2.5 1 1 0 1 1 1 1 AAA ATPase domain Ank_2 PF12796.7 CRK12764.1 - 0.0013 19.2 0.0 0.0029 18.1 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) NB-ARC PF00931.22 CRK12764.1 - 0.0017 17.6 0.0 0.0038 16.4 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA PF00004.29 CRK12764.1 - 0.016 15.6 0.0 0.031 14.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 CRK12764.1 - 0.049 14.1 0.0 0.2 12.1 0.0 2.2 1 1 0 1 1 1 0 AAA domain Torsin PF06309.11 CRK12764.1 - 0.14 12.2 0.0 0.36 10.9 0.0 1.6 1 0 0 1 1 1 0 Torsin HECA PF15353.6 CRK12765.1 - 0.096 12.9 0.1 0.25 11.6 0.1 1.7 1 0 0 1 1 1 0 Headcase protein family homologue DUF871 PF05913.11 CRK12766.1 - 0.065 12.4 0.1 0.088 12.0 0.1 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF871) LUC7 PF03194.15 CRK12766.1 - 0.074 12.7 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 LUC7 N_terminus Ferric_reduct PF01794.19 CRK12767.1 - 2.3e-10 40.7 3.9 2.3e-10 40.7 3.9 2.4 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 CRK12767.1 - 3.7e-07 30.2 0.1 6.8e-07 29.3 0.1 1.4 1 0 0 1 1 1 1 FAD-binding domain YqhR PF11085.8 CRK12767.1 - 0.02 14.8 0.9 0.053 13.4 0.6 1.8 2 0 0 2 2 2 0 Conserved membrane protein YqhR DUF751 PF05421.11 CRK12767.1 - 0.12 13.1 1.4 0.64 10.8 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF751) DUF2304 PF10066.9 CRK12767.1 - 0.26 11.5 5.7 4.7 7.5 1.8 2.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) Uso1_p115_C PF04871.13 CRK12768.1 - 0.73 10.2 24.4 0.22 11.9 5.2 2.6 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Mto2_bdg PF12808.7 CRK12768.1 - 1.8 8.9 14.1 3.9 7.9 1.5 4.0 3 1 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Swi5 PF07061.11 CRK12768.1 - 3.3 7.9 20.0 17 5.6 0.2 3.7 3 1 0 3 3 3 0 Swi5 ATG16 PF08614.11 CRK12768.1 - 3.7 7.7 33.0 4.2e+02 1.0 33.0 2.7 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Syntaxin-6_N PF09177.11 CRK12768.1 - 8.4 7.0 15.9 2.8e+03 -1.1 15.9 3.0 1 1 0 1 1 1 0 Syntaxin 6, N-terminal bZIP_1 PF00170.21 CRK12769.1 - 2.3e-06 27.6 3.8 2.3e-06 27.6 3.8 1.9 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 CRK12769.1 - 0.43 10.7 6.5 1.2 9.2 6.5 1.7 1 0 0 1 1 1 0 Basic region leucine zipper Sugar_tr PF00083.24 CRK12770.1 - 3.9e-23 82.0 14.1 4.8e-23 81.7 14.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK12770.1 - 1.5e-16 60.3 14.9 1.5e-16 60.3 14.9 1.7 1 1 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 CRK12770.1 - 0.0046 15.6 8.2 0.007 15.0 8.2 1.4 1 1 0 1 1 1 1 MFS/sugar transport protein TRI12 PF06609.13 CRK12770.1 - 0.0054 15.2 1.9 0.0063 15.0 1.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3425 PF11905.8 CRK12771.1 - 1.8e-07 31.1 0.2 1.8e-07 31.1 0.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 CRK12771.1 - 0.1 12.7 6.7 0.18 11.9 6.7 1.4 1 0 0 1 1 1 0 bZIP transcription factor OrfB_IS605 PF01385.19 CRK12771.1 - 0.77 10.0 4.7 1.1 9.5 3.4 1.9 1 1 1 2 2 2 0 Probable transposase NPR2 PF06218.11 CRK12774.1 - 1e-63 215.7 0.0 6.3e-44 150.4 0.0 2.0 1 1 1 2 2 2 2 Nitrogen permease regulator 2 WD40 PF00400.32 CRK12776.1 - 5.4e-13 49.2 5.2 3.5e-05 24.5 1.6 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK12776.1 - 0.0001 22.5 0.0 2.6 8.4 0.0 3.4 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain OTU PF02338.19 CRK12783.1 - 1.2e-13 51.6 0.0 1.3e-13 51.5 0.0 1.0 1 0 0 1 1 1 1 OTU-like cysteine protease Ribosomal_L13e PF01294.18 CRK12800.1 - 2.2e-24 86.3 0.0 2.2e-24 86.3 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L13e ATG13 PF10033.9 CRK12817.1 - 3.4e-76 256.1 0.0 5.6e-76 255.4 0.0 1.4 1 0 0 1 1 1 1 Autophagy-related protein 13 VHS PF00790.19 CRK12817.1 - 9.5e-35 119.5 0.1 1.9e-34 118.5 0.1 1.5 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.28 CRK12817.1 - 3e-15 55.6 0.0 5.5e-15 54.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CRK12817.1 - 4.7e-14 51.8 0.1 9.6e-14 50.8 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 CRK12817.1 - 1.1e-13 50.7 0.1 2.2e-13 49.8 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.14 CRK12817.1 - 4.9e-10 39.6 1.8 4.9e-10 39.6 1.8 1.9 2 0 0 2 2 2 1 GAT domain UIM PF02809.20 CRK12817.1 - 0.039 13.9 5.8 0.11 12.5 5.8 1.8 1 0 0 1 1 1 0 Ubiquitin interaction motif SNF2_N PF00176.23 CRK12818.1 - 3.1e-67 226.8 4.0 9.7e-66 221.9 2.3 3.1 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CRK12818.1 - 1.6e-17 63.8 0.1 1.1e-16 61.2 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CRK12818.1 - 2.9e-05 23.9 0.0 0.0001 22.2 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 CRK12818.1 - 3e-05 24.1 0.0 0.00012 22.1 0.0 2.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit BUD22 PF09073.10 CRK12819.1 - 9.7e-86 288.8 52.8 4.4e-85 286.6 52.8 1.8 1 1 0 1 1 1 1 BUD22 DUF2407_C PF13373.6 CRK12819.1 - 0.0085 16.3 1.7 0.032 14.4 1.7 2.0 1 0 0 1 1 1 1 DUF2407 C-terminal domain SPT16 PF08644.11 CRK12819.1 - 0.032 14.4 3.9 4.1 7.6 0.2 2.6 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) FMN_dh PF01070.18 CRK12819.1 - 0.047 12.7 0.2 0.089 11.8 0.2 1.4 1 0 0 1 1 1 0 FMN-dependent dehydrogenase VIT1 PF01988.19 CRK12819.1 - 0.32 10.8 4.3 1 9.2 0.3 2.6 2 0 0 2 2 2 0 VIT family adh_short_C2 PF13561.6 CRK12820.1 - 4.8e-38 131.0 1.4 6.9e-37 127.2 1.4 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRK12820.1 - 2.6e-33 115.2 0.5 3.9e-33 114.6 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CRK12820.1 - 3.6e-11 43.3 0.6 5.9e-11 42.6 0.6 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 CRK12820.1 - 0.00093 18.4 0.0 0.0016 17.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 CRK12820.1 - 0.0029 17.5 1.1 0.0029 17.5 1.1 1.4 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 CRK12820.1 - 0.011 15.2 0.2 0.021 14.3 0.2 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Methyltransf_25 PF13649.6 CRK12820.1 - 0.079 13.7 0.0 0.2 12.4 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain EF-hand_7 PF13499.6 CRK12821.1 - 7.1e-13 48.8 0.0 1.3e-08 35.1 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CRK12821.1 - 8.4e-09 34.7 0.0 0.055 13.4 0.0 3.7 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 CRK12821.1 - 3e-08 33.4 2.2 2.1e-07 30.7 0.4 3.0 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_1 PF00036.32 CRK12821.1 - 6.3e-08 31.6 0.0 0.14 11.8 0.1 3.6 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.6 CRK12821.1 - 0.00023 21.4 0.0 0.0076 16.6 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain MgtE_N PF03448.17 CRK12821.1 - 0.054 14.1 0.1 0.13 12.8 0.0 1.6 2 0 0 2 2 2 0 MgtE intracellular N domain EF-hand_11 PF08976.11 CRK12821.1 - 0.14 13.1 0.1 0.39 11.6 0.0 1.8 2 0 0 2 2 2 0 EF-hand domain ParA PF10609.9 CRK12822.1 - 2e-92 309.1 0.2 2.4e-92 308.9 0.2 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 CRK12822.1 - 6.1e-11 42.5 0.0 2.1e-10 40.7 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 CRK12822.1 - 1.1e-08 35.2 0.1 2.2e-07 31.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 CRK12822.1 - 0.00012 21.5 0.0 0.00015 21.1 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ Fer4_NifH PF00142.18 CRK12822.1 - 0.00067 19.2 0.0 0.13 11.7 0.0 2.3 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.15 CRK12822.1 - 0.0007 18.9 0.5 0.019 14.2 0.1 2.6 2 1 1 3 3 3 1 Anion-transporting ATPase CBP_BcsQ PF06564.12 CRK12822.1 - 0.0045 16.5 0.4 0.027 14.0 0.1 1.9 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ AAA_25 PF13481.6 CRK12822.1 - 0.019 14.5 0.0 0.042 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 CRK12822.1 - 0.031 13.3 0.1 0.054 12.5 0.1 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF561 PF04481.12 CRK12822.1 - 0.1 11.8 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF561) CLP1_P PF16575.5 CRK12822.1 - 0.15 11.8 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Tudor_3 PF18115.1 CRK12823.1 - 1.9e-06 27.6 0.1 3.1e-06 26.9 0.1 1.4 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain DUF4537 PF15057.6 CRK12823.1 - 6.2e-05 23.0 0.0 0.00011 22.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) FlxA PF14282.6 CRK12823.1 - 0.02 14.9 0.2 0.02 14.9 0.2 2.1 3 0 0 3 3 3 0 FlxA-like protein LBR_tudor PF09465.10 CRK12823.1 - 0.022 14.6 0.1 0.055 13.3 0.0 1.7 2 0 0 2 2 2 0 Lamin-B receptor of TUDOR domain DUF1325 PF07039.11 CRK12823.1 - 0.038 14.1 1.5 0.057 13.5 0.3 1.8 2 0 0 2 2 2 0 SGF29 tudor-like domain IL11 PF07400.11 CRK12823.1 - 0.12 12.0 0.1 0.19 11.4 0.1 1.3 1 0 0 1 1 1 0 Interleukin 11 Virul_Fac PF10139.9 CRK12823.1 - 0.15 10.3 1.2 0.23 9.7 1.2 1.2 1 0 0 1 1 1 0 Putative bacterial virulence factor TCO89 PF10452.9 CRK12824.1 - 1.3e-06 27.7 5.6 0.0069 15.4 0.0 2.2 2 0 0 2 2 2 2 TORC1 subunit TCO89 Mito_carr PF00153.27 CRK12825.1 - 1.8e-53 178.4 4.6 3.6e-18 65.3 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CRK12825.1 - 1.1 8.3 5.1 9.7 5.3 4.8 2.6 1 1 0 1 1 1 0 Gammaproteobacterial serine protease UCH_1 PF13423.6 CRK12827.1 - 1e-40 140.3 0.3 1.6e-40 139.7 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Cytochrom_D1 PF02239.16 CRK12827.1 - 0.16 10.5 0.1 0.35 9.3 0.1 1.5 1 1 0 1 1 1 0 Cytochrome D1 heme domain F_bP_aldolase PF01116.20 CRK12828.1 - 1.5e-55 188.7 0.0 1.2e-30 106.9 0.1 2.3 2 0 0 2 2 2 2 Fructose-bisphosphate aldolase class-II TRAUB PF08164.12 CRK12828.1 - 1.5e-29 102.4 0.2 1.5e-29 102.4 0.2 2.4 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal Chal_sti_synt_N PF00195.19 CRK12828.1 - 1.4e-21 77.0 0.1 2.5e-21 76.1 0.1 1.3 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain AATF-Che1 PF13339.6 CRK12828.1 - 3.7e-21 76.3 1.2 7.4e-21 75.3 0.1 2.0 2 0 0 2 2 2 1 Apoptosis antagonizing transcription factor Chal_sti_synt_C PF02797.15 CRK12828.1 - 3.5e-15 56.3 0.0 2.4e-13 50.4 0.0 2.5 2 0 0 2 2 2 1 Chalcone and stilbene synthases, C-terminal domain FAE1_CUT1_RppA PF08392.12 CRK12828.1 - 2.1e-05 24.0 0.0 3.5e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III_C PF08541.10 CRK12828.1 - 0.0025 17.9 0.0 0.09 13.0 0.0 3.1 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Chal_sti_synt_N PF00195.19 CRK12829.1 - 3.1e-22 79.1 0.0 4.7e-22 78.5 0.0 1.3 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain Chal_sti_synt_C PF02797.15 CRK12829.1 - 4.2e-19 69.0 0.0 8.6e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain FAE1_CUT1_RppA PF08392.12 CRK12829.1 - 3.8e-06 26.4 0.0 5.7e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III_C PF08541.10 CRK12829.1 - 2.7e-05 24.3 0.0 0.0009 19.4 0.0 2.4 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Thiolase_N PF00108.23 CRK12829.1 - 0.074 12.4 0.5 0.16 11.3 0.1 1.8 2 0 0 2 2 2 0 Thiolase, N-terminal domain TRAUB PF08164.12 CRK12830.1 - 5.6e-29 100.5 0.2 5.6e-29 100.5 0.2 3.2 3 0 0 3 3 3 2 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 CRK12830.1 - 6.1e-27 95.0 0.4 6.1e-27 95.0 0.4 3.1 4 2 0 4 4 4 1 Apoptosis antagonizing transcription factor Fungal_trans PF04082.18 CRK12831.1 - 1.5e-12 47.1 0.2 3.9e-12 45.8 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK12831.1 - 1.3e-05 25.2 4.3 2.6e-05 24.3 4.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HalX PF08663.10 CRK12831.1 - 0.036 14.4 0.6 0.089 13.1 0.6 1.6 1 0 0 1 1 1 0 HalX domain P63C PF10546.9 CRK12831.1 - 0.047 14.3 1.5 0.22 12.1 0.2 2.5 1 1 2 3 3 3 0 P63C domain Occludin_ELL PF07303.13 CRK12831.1 - 0.31 11.8 1.5 1.4 9.7 0.3 2.4 2 0 0 2 2 2 0 Occludin homology domain DASH_Dad3 PF08656.10 CRK12831.1 - 4 7.6 5.6 10 6.3 0.9 2.7 2 1 0 2 2 2 0 DASH complex subunit Dad3 Pyr_redox_2 PF07992.14 CRK12832.1 - 2.1e-39 135.5 0.1 2.8e-39 135.1 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CRK12832.1 - 2.6e-12 47.1 0.4 2.9e-11 43.8 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CRK12832.1 - 6.1e-06 25.7 0.0 1.4e-05 24.5 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CRK12832.1 - 0.00022 20.5 0.2 0.00084 18.6 0.1 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 CRK12832.1 - 0.00058 19.5 0.6 2.1 7.8 0.0 3.9 4 0 0 4 4 4 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CRK12832.1 - 0.0011 18.1 0.4 0.78 8.7 0.1 2.8 3 0 0 3 3 3 2 FAD binding domain Trp_halogenase PF04820.14 CRK12832.1 - 0.0019 17.1 0.9 1.1 8.0 0.1 2.8 2 1 1 3 3 3 2 Tryptophan halogenase Thi4 PF01946.17 CRK12832.1 - 0.0053 16.0 0.0 0.7 9.1 0.0 2.3 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.6 CRK12832.1 - 0.0071 16.3 0.6 12 5.8 0.1 4.1 3 1 1 4 4 4 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 CRK12832.1 - 0.011 16.0 0.2 4.5 7.6 0.0 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 CRK12832.1 - 0.013 14.5 0.3 0.16 11.0 0.0 2.7 4 0 0 4 4 4 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 CRK12832.1 - 0.019 14.3 0.2 1.3 8.3 0.1 2.6 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 CRK12832.1 - 0.03 13.1 1.3 0.3 9.7 0.1 2.8 3 0 0 3 3 3 0 HI0933-like protein DUF2633 PF11119.8 CRK12832.1 - 0.052 13.5 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) GIDA PF01134.22 CRK12832.1 - 4.3 6.3 8.4 1.1 8.3 0.5 3.1 3 1 0 3 3 3 0 Glucose inhibited division protein A Acetyltransf_10 PF13673.7 CRK12833.1 - 0.00028 20.8 0.0 0.00047 20.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CRK12833.1 - 0.006 17.0 0.0 0.011 16.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CRK12833.1 - 0.037 14.2 0.0 0.056 13.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Carb_anhydrase PF00194.21 CRK12834.1 - 2.3e-20 73.2 2.0 3.7e-20 72.6 2.0 1.3 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase DUF3425 PF11905.8 CRK12834.1 - 9.1e-17 61.2 0.0 2.2e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) GST_N_2 PF13409.6 CRK12834.1 - 5.1e-07 29.9 0.0 1.2e-06 28.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 CRK12834.1 - 3e-06 27.6 0.0 3.8e-05 24.0 0.0 2.5 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CRK12834.1 - 6.2e-05 22.9 1.2 0.00026 21.0 1.1 2.2 2 0 0 2 2 1 1 Glutathione S-transferase, C-terminal domain DUF2722 PF10846.8 CRK12834.1 - 0.0027 16.7 0.9 0.0053 15.8 0.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Activator_LAG-3 PF11498.8 CRK12834.1 - 0.027 13.5 18.0 0.043 12.8 18.0 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 TFIIA PF03153.13 CRK12834.1 - 0.044 13.8 7.6 0.086 12.8 7.6 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CRK12834.1 - 0.14 11.8 12.2 2.3 7.8 12.2 2.1 2 0 0 2 2 2 0 Spt20 family GST_C_3 PF14497.6 CRK12834.1 - 0.14 12.3 0.0 0.35 11.1 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Pex14_N PF04695.13 CRK12834.1 - 0.17 12.5 7.8 0.59 10.8 6.5 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Polyketide_cyc2 PF10604.9 CRK12835.1 - 0.029 14.6 5.5 0.11 12.8 5.2 2.3 1 1 1 2 2 2 0 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 CRK12835.1 - 0.029 14.6 0.6 0.052 13.8 0.6 1.4 1 1 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Dioxygenase_C PF00775.21 CRK12836.1 - 2.2e-32 111.9 0.0 3.6e-32 111.3 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 CRK12836.1 - 2.7e-31 107.2 0.0 4.9e-31 106.4 0.0 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 CRK12836.1 - 9.2e-05 22.6 0.0 0.00028 21.1 0.0 1.8 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain Big_1 PF02369.16 CRK12836.1 - 0.037 14.0 0.0 0.098 12.7 0.0 1.7 1 1 0 1 1 1 0 Bacterial Ig-like domain (group 1) DUF824 PF05688.11 CRK12836.1 - 0.097 12.5 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Salmonella repeat of unknown function (DUF824) Invasin_D3 PF09134.10 CRK12836.1 - 0.17 12.2 0.0 1.5 9.2 0.0 2.1 2 0 0 2 2 2 0 Invasin, domain 3 RRM_1 PF00076.22 CRK12837.1 - 3e-22 78.2 0.1 8e-12 44.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CRK12837.1 - 0.0014 18.7 0.0 1.9 8.7 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif ATP-sulfurylase PF01747.17 CRK12840.1 - 4.4e-87 291.0 0.1 6e-87 290.6 0.1 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 CRK12840.1 - 1.1e-55 187.9 0.0 1.7e-55 187.3 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.6 CRK12840.1 - 9.9e-53 178.1 0.0 1.6e-52 177.4 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain TRP PF06011.12 CRK12841.1 - 1.6e-100 336.8 18.7 2.6e-100 336.2 18.7 1.3 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 CRK12841.1 - 4.1e-32 111.5 0.0 7.1e-32 110.7 0.0 1.4 1 0 0 1 1 1 1 ML-like domain Semialdhyde_dhC PF02774.18 CRK12842.1 - 1.7e-37 129.2 0.0 2.3e-37 128.9 0.0 1.1 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 CRK12842.1 - 6.7e-23 81.4 0.0 5e-22 78.6 0.0 2.3 2 1 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 CRK12842.1 - 0.031 14.4 0.0 0.061 13.4 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus TRI12 PF06609.13 CRK12843.1 - 2.1e-80 270.8 25.8 2.8e-80 270.4 25.8 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 CRK12843.1 - 2e-18 66.5 52.1 4.2e-18 65.4 49.4 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK12843.1 - 2.2e-08 33.4 18.6 2.2e-08 33.4 18.6 3.5 2 1 1 3 3 3 1 Sugar (and other) transporter Pox_A14 PF05767.12 CRK12843.1 - 0.012 15.8 0.3 0.012 15.8 0.3 3.1 4 0 0 4 4 4 0 Poxvirus virion envelope protein A14 TauD PF02668.16 CRK12844.1 - 1.2e-63 215.4 0.4 1.5e-63 215.1 0.4 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.16 CRK12845.1 - 2.3e-16 59.7 21.3 2.9e-16 59.4 20.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily HgmA PF04209.13 CRK12846.1 - 1.8e-186 619.9 0.0 2.2e-186 619.7 0.0 1.1 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Exo_endo_phos PF03372.23 CRK12847.1 - 1.2e-08 34.8 0.5 2.9e-08 33.5 0.5 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ank_2 PF12796.7 CRK12848.1 - 2.1e-31 108.3 0.2 1.1e-07 32.3 0.1 5.0 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) HET PF06985.11 CRK12848.1 - 6.1e-23 81.8 0.0 1.6e-22 80.4 0.0 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_3 PF13606.6 CRK12848.1 - 1.3e-22 77.4 0.6 0.049 14.2 0.0 7.9 7 0 0 7 7 7 7 Ankyrin repeat Ank_4 PF13637.6 CRK12848.1 - 1.8e-21 76.2 2.6 0.00014 22.3 0.1 6.0 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 CRK12848.1 - 2e-21 75.4 0.2 0.036 14.5 0.1 7.6 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 CRK12848.1 - 2e-20 72.6 3.3 3.8e-05 23.9 0.1 6.2 3 1 3 6 6 6 6 Ankyrin repeats (many copies) Helo_like_N PF17111.5 CRK12848.1 - 0.0018 17.7 0.2 0.0041 16.5 0.2 1.6 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins AIB PF15334.6 CRK12848.1 - 0.021 14.2 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Aurora kinase A and ninein interacting protein CCDC144C PF14915.6 CRK12848.1 - 0.091 11.9 0.2 0.15 11.2 0.2 1.2 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region SesA PF17107.5 CRK12848.1 - 0.12 12.5 0.2 0.24 11.6 0.2 1.6 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases AA_kinase PF00696.28 CRK12849.1 - 9.3e-22 77.8 0.0 1.7e-21 76.9 0.0 1.4 2 0 0 2 2 2 1 Amino acid kinase family ACT PF01842.25 CRK12849.1 - 0.0039 16.9 0.0 0.011 15.5 0.0 1.7 2 0 0 2 2 2 1 ACT domain ACT_7 PF13840.6 CRK12849.1 - 0.015 15.1 0.1 0.026 14.3 0.1 1.4 1 0 0 1 1 1 0 ACT domain Complex1_LYR PF05347.15 CRK12850.1 - 8.9e-06 25.7 1.2 9.5e-06 25.6 1.2 1.0 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Ish1 PF10281.9 CRK12852.1 - 3e-05 24.2 0.0 3.7e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Putative stress-responsive nuclear envelope protein DNA_meth_N PF18284.1 CRK12852.1 - 0.044 13.7 0.7 0.14 12.1 0.2 1.8 2 0 0 2 2 2 0 DNA methylase N-terminal domain Mac PF12464.8 CRK12852.1 - 0.15 12.3 0.5 0.2 12.0 0.5 1.2 1 0 0 1 1 1 0 Maltose acetyltransferase Ribosomal_S21e PF01249.18 CRK12855.1 - 2.9e-19 69.0 0.2 3e-19 68.9 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e RL10P_insert PF17777.1 CRK12874.1 - 2.6e-22 78.6 0.0 5e-22 77.7 0.0 1.5 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 CRK12874.1 - 4.6e-18 65.6 3.6 4.6e-18 65.6 3.6 2.2 2 0 0 2 2 2 1 60s Acidic ribosomal protein Ribosomal_L10 PF00466.20 CRK12874.1 - 7e-11 42.2 0.0 1.9e-10 40.8 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L10 THOC2_N PF16134.5 CRK12895.1 - 2e-225 750.3 0.0 3.1e-225 749.6 0.0 1.3 1 0 0 1 1 1 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 CRK12895.1 - 1.2e-84 284.1 0.3 1.9e-84 283.4 0.3 1.4 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 CRK12895.1 - 1.1e-21 76.6 0.1 2.2e-21 75.7 0.1 1.5 1 0 0 1 1 1 1 Transcription- and export-related complex subunit PI-PLC-X PF00388.19 CRK12896.1 - 1.9e-06 27.5 0.0 3e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain WSC PF01822.19 CRK12897.1 - 5.7e-11 42.4 8.8 1.6e-10 41.0 8.8 1.7 1 0 0 1 1 1 1 WSC domain Adeno_E3_CR2 PF02439.15 CRK12897.1 - 8.1e-05 22.3 0.1 0.00014 21.5 0.1 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Podoplanin PF05808.11 CRK12897.1 - 0.00021 21.5 2.4 0.00046 20.3 2.4 1.6 1 0 0 1 1 1 1 Podoplanin SKG6 PF08693.10 CRK12897.1 - 0.0027 17.1 3.7 0.0064 15.9 3.7 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain CcmD PF04995.14 CRK12897.1 - 0.0056 16.7 0.3 0.013 15.6 0.3 1.7 1 0 0 1 1 1 1 Heme exporter protein D (CcmD) Mid2 PF04478.12 CRK12897.1 - 0.011 15.6 0.0 0.024 14.5 0.0 1.6 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Gram_pos_anchor PF00746.21 CRK12897.1 - 0.014 15.3 0.1 0.014 15.3 0.1 1.7 2 0 0 2 2 1 0 LPXTG cell wall anchor motif TMEM154 PF15102.6 CRK12897.1 - 0.027 14.4 0.1 0.069 13.0 0.1 1.7 1 1 0 1 1 1 0 TMEM154 protein family EphA2_TM PF14575.6 CRK12897.1 - 0.029 15.3 0.0 0.062 14.2 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Syndecan PF01034.20 CRK12897.1 - 0.034 14.1 0.0 0.059 13.3 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain PTP_tm PF18861.1 CRK12897.1 - 0.039 14.0 0.1 0.061 13.3 0.1 1.3 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J DUF2207 PF09972.9 CRK12897.1 - 0.083 11.6 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Phage_holin_2_1 PF04971.12 CRK12897.1 - 0.086 12.9 0.1 0.33 11.0 0.0 2.0 2 0 0 2 2 2 0 Bacteriophage P21 holin S DUF2755 PF10954.8 CRK12897.1 - 0.1 12.6 0.1 0.19 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2755) Glycophorin_A PF01102.18 CRK12897.1 - 0.12 12.6 1.6 0.57 10.4 1.6 2.2 1 1 0 1 1 1 0 Glycophorin A Phage_holin_2_4 PF16082.5 CRK12897.1 - 0.14 11.9 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like CFEM PF05730.11 CRK12898.1 - 3e-10 40.0 12.5 5.8e-10 39.1 12.5 1.5 1 0 0 1 1 1 1 CFEM domain Tad_C PF09977.9 CRK12898.1 - 0.039 15.2 0.2 0.76 11.0 0.0 2.5 2 0 0 2 2 2 0 Putative Tad-like Flp pilus-assembly GMC_oxred_C PF05199.13 CRK12899.1 - 4.1e-31 108.4 0.0 8.1e-31 107.5 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 CRK12899.1 - 2.9e-27 95.8 0.0 5.2e-24 85.1 0.0 2.4 2 0 0 2 2 2 2 GMC oxidoreductase Pyr_redox_2 PF07992.14 CRK12899.1 - 0.00025 20.4 0.0 0.0012 18.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CRK12899.1 - 0.00071 19.8 0.0 0.0019 18.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CRK12899.1 - 0.0086 15.2 0.3 0.016 14.3 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 CRK12899.1 - 0.026 13.8 0.3 0.043 13.0 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 CRK12899.1 - 0.028 13.5 0.0 0.04 13.0 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 CRK12899.1 - 0.099 11.9 0.1 9.7 5.3 0.1 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CRK12899.1 - 0.18 10.5 0.1 0.29 9.8 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein HHH PF00633.23 CRK12899.1 - 2.4 8.2 5.1 1.4 8.9 0.1 3.1 4 0 0 4 4 4 0 Helix-hairpin-helix motif 4HBT_2 PF13279.6 CRK12900.1 - 4.1e-19 69.3 0.0 7.7e-19 68.4 0.0 1.5 1 1 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 CRK12900.1 - 0.013 15.8 0.0 0.024 15.0 0.0 1.4 1 0 0 1 1 1 0 Thioesterase superfamily SKG6 PF08693.10 CRK12902.1 - 0.017 14.5 0.0 0.048 13.1 0.0 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Mid2 PF04478.12 CRK12902.1 - 0.037 13.9 0.0 0.09 12.6 0.0 1.6 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor TMF_DNA_bd PF12329.8 CRK12904.1 - 0.11 12.5 4.6 0.28 11.2 4.6 1.7 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding ERM PF00769.19 CRK12904.1 - 1 9.1 17.1 0.25 11.1 13.8 1.6 2 0 0 2 2 2 0 Ezrin/radixin/moesin family YabA PF06156.13 CRK12904.1 - 3.2 8.4 8.0 12 6.6 2.1 2.5 1 1 1 2 2 2 0 Initiation control protein YabA DUF4200 PF13863.6 CRK12904.1 - 9.6 6.6 17.6 0.048 14.1 4.2 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) RSN1_7TM PF02714.15 CRK12906.1 - 1.4e-85 286.9 22.7 1.4e-85 286.9 22.7 2.6 3 0 0 3 3 3 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 CRK12906.1 - 1.7e-44 151.4 1.3 1.7e-44 151.4 1.3 2.6 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 CRK12906.1 - 2.7e-37 128.7 0.0 3.9e-37 128.2 0.0 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 CRK12906.1 - 1.9e-31 108.1 0.1 4.1e-31 107.0 0.1 1.5 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter kleA_kleC PF17383.2 CRK12906.1 - 0.053 13.9 0.6 0.36 11.2 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized KorC regulated protein A COesterase PF00135.28 CRK12907.1 - 1.7e-82 278.0 0.9 3.3e-82 277.0 0.0 1.8 2 0 0 2 2 2 1 Carboxylesterase family RTA1 PF04479.13 CRK12907.1 - 8.5e-65 218.2 12.8 1.3e-64 217.6 12.8 1.3 1 0 0 1 1 1 1 RTA1 like protein Zn_clus PF00172.18 CRK12907.1 - 3e-07 30.4 8.8 6.1e-07 29.4 8.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_3 PF07859.13 CRK12907.1 - 5e-06 26.5 0.3 6.4e-05 22.9 0.2 2.9 2 1 0 2 2 2 1 alpha/beta hydrolase fold PPR_2 PF13041.6 CRK12908.1 - 1.2e-06 28.6 0.1 0.16 12.2 0.0 5.8 7 1 1 8 8 8 1 PPR repeat family PPR_long PF17177.4 CRK12908.1 - 0.00013 21.4 0.2 0.0025 17.2 0.1 2.7 3 0 0 3 3 3 1 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 CRK12908.1 - 0.00019 21.5 3.6 0.12 12.6 0.0 5.8 8 0 0 8 8 8 1 PPR repeat PPR_3 PF13812.6 CRK12908.1 - 0.0075 16.3 0.1 3.3 7.9 0.0 4.1 4 1 1 5 5 5 1 Pentatricopeptide repeat domain PPR_1 PF12854.7 CRK12908.1 - 0.022 14.4 3.0 0.19 11.4 0.0 3.6 4 0 0 4 4 4 0 PPR repeat TPR_2 PF07719.17 CRK12908.1 - 0.053 13.7 0.3 0.87 9.9 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Acyl_transf_1 PF00698.21 CRK12909.1 - 7.7e-169 561.2 0.0 4.5e-86 289.2 0.0 4.1 6 0 0 6 6 6 2 Acyl transferase domain FAS_N PF17828.1 CRK12909.1 - 8e-79 262.0 0.1 5.7e-38 129.8 0.0 2.6 2 0 0 2 2 2 2 N-terminal domain in fatty acid synthase subunit beta MaoC_dehydratas PF01575.19 CRK12909.1 - 2.5e-73 243.4 0.0 3.2e-35 120.4 0.0 2.6 2 0 0 2 2 2 2 MaoC like domain DUF1729 PF08354.10 CRK12909.1 - 1.6e-65 221.3 0.1 3.3e-65 220.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.6 CRK12909.1 - 8.7e-52 174.7 0.8 1.3e-24 86.8 0.0 3.4 4 0 0 4 4 4 2 N-terminal half of MaoC dehydratase SAT PF16073.5 CRK12909.1 - 2.6e-37 128.8 0.0 1.9e-36 126.0 0.0 2.4 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis DUF4914 PF16260.5 CRK12909.1 - 0.037 12.1 0.2 5.6 4.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4914) Lipase_3 PF01764.25 CRK12909.1 - 0.045 13.6 1.0 15 5.4 0.0 3.0 3 0 0 3 3 3 0 Lipase (class 3) Plant_all_beta PF10532.9 CRK12909.1 - 0.12 12.6 0.0 31 4.9 0.0 2.5 2 0 0 2 2 2 0 Plant specific N-all beta domain YajC PF02699.15 CRK12909.1 - 1.4 8.9 3.5 58 3.7 0.1 3.2 3 0 0 3 3 3 0 Preprotein translocase subunit FAS_I_H PF18314.1 CRK12912.1 - 1.1e-76 256.9 0.1 2.5e-76 255.8 0.1 1.6 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain ACPS PF01648.20 CRK12912.1 - 1.3e-16 60.8 0.0 3.9e-16 59.2 0.0 1.9 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily ketoacyl-synt PF00109.26 CRK12912.1 - 1.4e-11 44.5 0.0 3.2e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 CRK12912.1 - 0.0011 19.0 0.0 0.0033 17.4 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 CRK12912.1 - 0.0058 16.6 0.0 0.017 15.0 0.0 1.8 1 0 0 1 1 1 1 KR domain Ribosomal_S4 PF00163.19 CRK12912.1 - 0.042 14.8 0.5 0.14 13.1 0.5 1.9 1 0 0 1 1 1 0 Ribosomal protein S4/S9 N-terminal domain ACP_syn_III_C PF08541.10 CRK12912.1 - 0.056 13.6 0.1 0.2 11.8 0.1 1.9 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal DUF2681 PF10883.8 CRK12913.1 - 0.61 10.5 5.2 1.5 9.3 5.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) DUF4407 PF14362.6 CRK12913.1 - 0.89 8.8 10.7 0.98 8.7 10.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Mannosyl_trans3 PF11051.8 CRK12914.1 - 0.22 10.8 0.0 0.33 10.3 0.0 1.3 1 0 0 1 1 1 0 Mannosyltransferase putative Abhydrolase_1 PF00561.20 CRK12915.1 - 9.3e-24 84.4 0.0 8.5e-23 81.3 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CRK12915.1 - 1.9e-16 60.1 0.0 8e-15 54.7 0.0 3.0 3 0 0 3 3 3 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CRK12915.1 - 6.6e-15 56.3 0.3 3.9e-14 53.8 0.0 2.5 2 1 0 2 2 2 1 Alpha/beta hydrolase family DUF915 PF06028.11 CRK12915.1 - 3e-06 26.8 0.0 5.8e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.20 CRK12915.1 - 3.7e-05 23.5 0.0 0.0001 22.1 0.0 1.7 1 0 0 1 1 1 1 Putative esterase LIDHydrolase PF10230.9 CRK12915.1 - 0.011 15.3 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Ser_hydrolase PF06821.13 CRK12915.1 - 0.071 13.0 0.0 0.23 11.3 0.0 1.8 1 0 0 1 1 1 0 Serine hydrolase Chlorophyllase2 PF12740.7 CRK12915.1 - 0.15 10.9 0.0 0.25 10.2 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_2 PF02230.16 CRK12915.1 - 0.22 11.3 0.0 14 5.4 0.0 2.7 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Spo7 PF03907.13 CRK12916.1 - 2.1e-15 56.8 1.1 2.5e-15 56.6 1.1 1.1 1 0 0 1 1 1 1 Spo7-like protein Abhydrolase_1 PF00561.20 CRK12917.1 - 1.7e-24 86.9 0.0 1.1e-23 84.2 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CRK12917.1 - 1.9e-17 63.3 0.1 3.4e-15 56.0 0.0 3.5 4 0 0 4 4 4 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CRK12917.1 - 8.7e-15 55.9 0.0 2.6e-14 54.4 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.11 CRK12917.1 - 1.3e-06 28.0 0.0 3.1e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.20 CRK12917.1 - 1.4e-05 24.9 0.2 4.6e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 Putative esterase LIDHydrolase PF10230.9 CRK12917.1 - 0.0052 16.4 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Ser_hydrolase PF06821.13 CRK12917.1 - 0.041 13.7 0.0 0.1 12.4 0.0 1.7 1 0 0 1 1 1 0 Serine hydrolase Abhydrolase_2 PF02230.16 CRK12917.1 - 0.069 12.9 0.0 7.3 6.3 0.0 2.8 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.7 CRK12917.1 - 0.069 12.9 0.0 0.25 11.1 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 CRK12917.1 - 0.07 12.0 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme Thioesterase PF00975.20 CRK12917.1 - 0.1 12.7 0.2 0.91 9.6 0.1 2.5 2 1 0 2 2 2 0 Thioesterase domain TPR_10 PF13374.6 CRK12917.1 - 0.15 12.0 0.1 0.36 10.8 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Chlorophyllase PF07224.11 CRK12917.1 - 0.16 11.0 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase PGAP1 PF07819.13 CRK12917.1 - 0.16 11.7 0.0 0.44 10.2 0.0 1.7 2 0 0 2 2 2 0 PGAP1-like protein PLDc_2 PF13091.6 CRK12918.1 - 4.7e-12 45.9 0.0 3.5e-07 30.2 0.0 3.0 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 CRK12918.1 - 0.014 15.6 0.2 0.047 13.9 0.1 2.0 2 0 0 2 2 2 0 Phospholipase D Active site motif FAM70 PF14967.6 CRK12918.1 - 4.8 6.6 5.1 7.2 6.0 5.1 1.2 1 0 0 1 1 1 0 FAM70 protein VASt PF16016.5 CRK12919.1 - 2.1e-37 128.9 0.0 4.1e-37 127.9 0.0 1.5 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 CRK12919.1 - 3.9e-15 55.7 0.0 8.2e-15 54.7 0.0 1.5 1 0 0 1 1 1 1 GRAM domain ArAE_2_N PF10337.9 CRK12919.1 - 6.3e-15 55.2 1.1 1.2e-06 27.9 0.0 3.4 2 1 1 3 3 3 2 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 CRK12919.1 - 1.3e-09 38.2 17.3 1.3e-09 38.2 17.3 3.9 3 1 1 4 4 4 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 CRK12919.1 - 2.3e-05 24.4 0.3 4.4e-05 23.4 0.3 1.4 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 ALMT PF11744.8 CRK12919.1 - 1.6 7.5 14.6 0.036 12.9 5.7 2.4 2 1 0 3 3 3 0 Aluminium activated malate transporter ArAE_1 PF06081.11 CRK12919.1 - 6.1 7.0 20.2 0.24 11.6 9.2 3.2 3 0 0 3 3 3 0 Aromatic acid exporter family member 1 Ist1 PF03398.14 CRK12920.1 - 1.4e-60 204.0 2.3 1.9e-60 203.5 2.3 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Clat_adaptor_s PF01217.20 CRK12921.1 - 5.3e-56 188.5 1.5 5.8e-56 188.4 1.5 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PDZ_1 PF12812.7 CRK12922.1 - 3.1e-53 177.7 0.1 2.2e-34 117.3 0.0 2.6 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.6 CRK12922.1 - 1.3e-23 84.5 1.3 1.2e-20 74.9 0.0 2.5 2 0 0 2 2 2 2 Trypsin-like peptidase domain PDZ_2 PF13180.6 CRK12922.1 - 1.1e-14 54.5 0.9 5.3e-06 26.7 0.0 4.3 4 0 0 4 4 4 3 PDZ domain PDZ_6 PF17820.1 CRK12922.1 - 3.8e-14 52.3 0.1 2.1e-05 24.3 0.1 4.0 4 0 0 4 4 4 3 PDZ domain PDZ PF00595.24 CRK12922.1 - 1.5e-09 38.1 0.0 3.6e-05 24.0 0.0 3.7 4 0 0 4 4 4 2 PDZ domain Tricorn_PDZ PF14685.6 CRK12922.1 - 0.03 14.3 2.2 2.5 8.1 0.2 3.5 4 0 0 4 4 4 0 Tricorn protease PDZ domain Myb_DNA-bind_6 PF13921.6 CRK12923.1 - 0.015 15.5 0.0 0.026 14.8 0.0 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 CRK12923.1 - 0.028 14.6 0.0 0.063 13.5 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain SWI-SNF_Ssr4 PF08549.10 CRK12923.1 - 3.7 6.1 18.1 6.2 5.3 18.0 1.6 1 1 0 1 1 1 0 Fungal domain of unknown function (DUF1750) DTHCT PF08070.11 CRK12923.1 - 8.8 7.1 24.2 2.7 8.8 18.8 2.6 2 1 1 3 3 3 0 DTHCT (NUC029) region INCENP_ARK-bind PF03941.15 CRK12924.1 - 4e-19 68.3 1.4 4e-19 68.3 1.4 2.8 3 0 0 3 3 3 1 Inner centromere protein, ARK binding region SMC_N PF02463.19 CRK12925.1 - 1.6e-56 191.2 18.2 9.7e-55 185.4 18.2 3.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CRK12925.1 - 3e-21 75.9 0.8 1.3e-20 73.9 0.3 2.5 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 CRK12925.1 - 3.4e-10 40.2 5.7 0.00019 21.3 0.3 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CRK12925.1 - 1.6e-05 25.5 34.4 1.6e-05 25.5 34.4 5.4 2 2 1 3 3 2 1 AAA domain AAA_29 PF13555.6 CRK12925.1 - 0.00011 21.8 0.1 0.00026 20.7 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MscS_porin PF12795.7 CRK12925.1 - 0.0017 18.0 18.4 0.0017 18.0 18.4 4.9 2 2 2 4 4 4 1 Mechanosensitive ion channel porin domain Tup_N PF08581.10 CRK12925.1 - 0.0085 16.4 2.3 0.0085 16.4 2.3 7.1 5 4 4 9 9 9 1 Tup N-terminal HIP1_clath_bdg PF16515.5 CRK12925.1 - 0.016 15.8 6.3 0.016 15.8 6.3 7.8 3 2 5 8 8 6 0 Clathrin-binding domain of Huntingtin-interacting protein 1 HSBP1 PF06825.12 CRK12925.1 - 0.043 13.7 0.4 0.043 13.7 0.4 3.1 2 0 0 2 2 2 0 Heat shock factor binding protein 1 VPS11_C PF12451.8 CRK12925.1 - 0.56 10.5 3.0 3.3 8.0 0.7 3.6 2 0 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal DUF3545 PF12065.8 CRK12925.1 - 3.8 7.6 9.3 3 7.9 2.4 3.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3545) ABC_tran PF00005.27 CRK12925.1 - 3.9 8.0 30.5 95 3.5 8.8 5.5 2 2 0 2 2 2 0 ABC transporter MOSC PF03473.17 CRK12926.1 - 1.3e-21 76.9 0.0 4.4e-21 75.3 0.0 1.8 2 0 0 2 2 2 1 MOSC domain MOSC_N PF03476.16 CRK12926.1 - 7.1e-10 38.8 0.0 1.6e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Fungal_trans_2 PF11951.8 CRK12928.1 - 4.6e-11 42.2 1.2 1e-10 41.0 1.2 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain GvpG PF05120.12 CRK12928.1 - 0.0031 17.5 0.1 0.0098 15.9 0.1 1.8 1 0 0 1 1 1 1 Gas vesicle protein G Mob1_phocein PF03637.17 CRK12929.1 - 3.5e-22 79.2 0.3 5.9e-22 78.5 0.3 1.3 1 0 0 1 1 1 1 Mob1/phocein family CxC6 PF18721.1 CRK12929.1 - 0.035 14.4 2.7 0.096 13.0 2.7 1.7 1 0 0 1 1 1 0 CxC6 like cysteine cluster associated with KDZ transposases cobW PF02492.19 CRK12931.1 - 4e-48 163.3 0.2 5.2e-48 163.0 0.2 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 CRK12931.1 - 3.8e-06 26.9 0.3 0.1 12.5 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase CobW_C PF07683.14 CRK12931.1 - 2.4e-05 24.2 0.0 4.9e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain Septin PF00735.18 CRK12931.1 - 0.00097 18.5 0.6 0.2 10.9 0.0 2.6 2 1 0 2 2 2 2 Septin AAA_22 PF13401.6 CRK12931.1 - 0.0032 17.7 0.4 0.36 11.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 CRK12931.1 - 0.0035 16.4 0.4 2.2 7.2 0.0 2.9 3 0 0 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 CRK12931.1 - 0.0049 16.4 0.1 1.8 8.1 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 CRK12931.1 - 0.0091 16.4 0.0 0.047 14.1 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain ATP_bind_1 PF03029.17 CRK12931.1 - 0.011 15.6 0.9 0.074 12.8 0.9 2.0 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_23 PF13476.6 CRK12931.1 - 0.011 16.3 0.3 0.021 15.3 0.1 1.6 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 CRK12931.1 - 0.011 15.8 0.0 0.021 14.9 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.6 CRK12931.1 - 0.039 13.7 0.3 0.11 12.2 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain T2SSE PF00437.20 CRK12931.1 - 0.047 12.7 0.2 0.11 11.5 0.2 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.27 CRK12931.1 - 0.055 14.0 0.4 0.75 10.3 0.1 2.5 3 0 0 3 3 2 0 ABC transporter TsaE PF02367.17 CRK12931.1 - 0.072 13.1 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 CRK12931.1 - 0.078 12.7 0.7 0.31 10.7 0.1 2.0 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 CRK12931.1 - 0.1 12.5 0.1 0.19 11.6 0.1 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 CRK12931.1 - 0.16 12.0 1.7 1 9.4 0.0 2.5 3 0 0 3 3 2 0 AAA domain Chorismate_synt PF01264.21 CRK12933.1 - 7.1e-42 143.3 0.1 7.8e-42 143.1 0.1 1.0 1 0 0 1 1 1 1 Chorismate synthase TPR_2 PF07719.17 CRK12936.1 - 3e-09 36.3 0.0 4.7e-08 32.5 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 CRK12936.1 - 2.4e-07 30.3 0.0 1.4e-06 27.9 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 CRK12936.1 - 1.1e-05 25.9 0.0 2.8e-05 24.7 0.0 1.8 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 CRK12936.1 - 1.1e-05 25.8 0.3 9.4e-05 22.9 0.0 2.4 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 CRK12936.1 - 4.5e-05 23.6 0.1 0.0027 18.0 0.0 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 CRK12936.1 - 6.9e-05 22.4 0.0 0.00061 19.4 0.0 2.4 2 1 0 2 2 2 1 TPR repeat TPR_8 PF13181.6 CRK12936.1 - 0.00055 19.9 0.0 0.0025 17.9 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 CRK12936.1 - 0.0006 20.0 0.1 0.067 13.6 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 CRK12936.1 - 0.0043 17.5 1.1 0.017 15.6 0.2 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.6 CRK12936.1 - 0.0067 15.7 0.0 0.0076 15.5 0.0 1.3 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_9 PF13371.6 CRK12936.1 - 0.0076 16.4 0.2 0.016 15.4 0.1 1.6 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_4 PF07721.14 CRK12936.1 - 0.0098 16.4 1.6 0.15 12.7 0.0 3.3 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 CRK12936.1 - 0.011 16.4 0.1 0.53 11.0 0.0 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 CRK12936.1 - 0.013 15.5 0.0 0.035 14.1 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CRK12936.1 - 0.021 15.0 0.0 0.039 14.2 0.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 CRK12936.1 - 0.061 13.2 0.1 0.24 11.3 0.0 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat dCMP_cyt_deam_1 PF00383.23 CRK12937.1 - 1.3e-12 47.5 0.3 1.4e-12 47.3 0.3 1.0 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 CRK12937.1 - 6.9e-05 23.1 0.4 7.6e-05 22.9 0.4 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Glyco_hydro_76 PF03663.14 CRK12939.1 - 1.6e-06 27.9 2.2 0.00015 21.4 2.2 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 KH_8 PF17903.1 CRK12941.1 - 2.6e-13 49.8 0.0 4.6e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Krr1 KH1 domain DUF2235 PF09994.9 CRK12983.1 - 5e-42 144.2 0.0 5.9e-42 144.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) AJAP1_PANP_C PF15298.6 CRK12984.1 - 0.00059 20.1 2.1 0.00085 19.6 2.1 1.2 1 0 0 1 1 1 1 AJAP1/PANP C-terminus Fungal_trans PF04082.18 CRK12985.1 - 1e-11 44.4 0.5 1.5e-11 43.8 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK12985.1 - 3.9e-05 23.7 14.5 6.8e-05 22.9 14.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RabGAP-TBC PF00566.18 CRK12986.1 - 7.8e-47 159.7 0.0 1.3e-46 159.0 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain LRR_4 PF12799.7 CRK12987.1 - 4.6e-24 84.1 37.7 1.9e-05 24.9 5.3 8.5 9 1 1 10 10 10 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CRK12987.1 - 1.7e-15 56.5 29.3 0.00023 20.8 0.1 7.1 4 1 4 8 8 8 6 Leucine rich repeat LRR_9 PF14580.6 CRK12987.1 - 7.7e-10 38.5 9.7 0.00022 20.8 0.5 4.2 2 1 1 4 4 4 3 Leucine-rich repeat LRR_6 PF13516.6 CRK12987.1 - 0.33 11.1 16.2 9.1 6.6 0.0 6.3 7 0 0 7 7 7 0 Leucine Rich repeat Vpu PF00558.19 CRK12987.1 - 1.8 8.4 4.0 21 5.0 0.9 2.6 2 0 0 2 2 2 0 Vpu protein LRR_1 PF00560.33 CRK12987.1 - 9.1 7.3 22.5 1e+02 4.1 0.4 8.3 7 1 0 7 7 7 0 Leucine Rich Repeat IPK PF03770.16 CRK12989.1 - 1.7e-54 184.7 0.0 2.6e-54 184.1 0.0 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase CN_hydrolase PF00795.22 CRK12989.1 - 2.1e-17 63.3 0.0 4e-12 46.0 0.0 2.3 2 0 0 2 2 2 2 Carbon-nitrogen hydrolase Aminotran_1_2 PF00155.21 CRK12989.1 - 0.084 12.0 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II SKG6 PF08693.10 CRK12990.1 - 0.9 9.0 4.0 2 7.9 4.0 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Clathrin PF00637.20 CRK12991.1 - 5.8e-23 81.3 1.0 1.4e-22 80.1 1.0 1.6 1 0 0 1 1 1 1 Region in Clathrin and VPS VPS11_C PF12451.8 CRK12991.1 - 1e-18 67.3 0.0 2e-18 66.3 0.0 1.6 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal HATPase_c_3 PF13589.6 CRK12991.1 - 9.5e-18 64.3 0.0 2.1e-17 63.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.11 CRK12991.1 - 6.2e-10 39.0 0.5 3.2e-08 33.5 0.0 3.3 3 1 0 3 3 3 1 MutL C terminal dimerisation domain zf-C3H2C3 PF17122.5 CRK12991.1 - 1.3e-06 28.3 4.3 3.2e-06 27.1 4.3 1.7 1 0 0 1 1 1 1 Zinc-finger HATPase_c PF02518.26 CRK12991.1 - 1.9e-05 25.1 0.3 0.0046 17.4 0.0 3.3 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase zf-C3HC4_2 PF13923.6 CRK12991.1 - 5.4e-05 22.9 4.1 0.00016 21.4 4.1 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CRK12991.1 - 0.001 19.0 4.1 0.002 18.0 4.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 CRK12991.1 - 0.014 15.7 3.6 0.033 14.5 3.6 1.7 1 0 0 1 1 1 0 Ring finger domain zf-rbx1 PF12678.7 CRK12991.1 - 0.05 13.9 2.4 0.12 12.7 2.4 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 CRK12991.1 - 0.05 13.6 2.6 0.12 12.5 2.6 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 CRK12991.1 - 1.4 8.9 7.4 0.12 12.2 2.5 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Chorismate_synt PF01264.21 CRK12992.1 - 1.9e-69 233.9 0.0 2.2e-69 233.7 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase Chorismate_synt PF01264.21 CRK12995.1 - 1.2e-136 454.7 0.0 1.4e-136 454.5 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase DUF3224 PF11528.8 CRK12995.1 - 0.0048 16.7 0.0 0.0078 16.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3224) BPL_LplA_LipB PF03099.19 CRK12997.1 - 0.00071 19.5 0.0 0.052 13.5 0.0 3.2 2 1 0 2 2 2 1 Biotin/lipoate A/B protein ligase family NRIP1_repr_3 PF15689.5 CRK12997.1 - 0.058 13.7 0.2 20 5.6 0.0 2.4 2 0 0 2 2 2 0 Nuclear receptor-interacting protein 1 repression 3 tRNA-synt_1b PF00579.25 CRK12998.1 - 9.7e-06 25.1 0.0 1.4e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) VPS11_C PF12451.8 CRK12999.1 - 3.3e-19 68.8 0.0 6e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 CRK12999.1 - 5.3e-07 29.6 4.3 9.7e-07 28.7 4.3 1.4 1 0 0 1 1 1 1 Zinc-finger zf-C3HC4_2 PF13923.6 CRK12999.1 - 4.8e-05 23.1 4.1 4.8e-05 23.1 4.1 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CRK12999.1 - 0.00033 20.5 4.1 0.0006 19.7 4.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 CRK12999.1 - 0.0058 16.9 3.6 0.0098 16.2 3.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 CRK12999.1 - 0.016 15.5 2.2 0.03 14.6 2.2 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 CRK12999.1 - 0.016 15.2 2.6 0.035 14.1 2.6 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 CRK12999.1 - 0.017 15.0 2.5 0.037 13.9 2.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) HypA PF01155.19 CRK12999.1 - 0.25 11.4 0.8 0.6 10.1 0.8 1.6 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RING-like PF08746.11 CRK12999.1 - 1.6 9.1 3.9 3.6 8.0 3.9 1.6 1 0 0 1 1 1 0 RING-like domain zf-RING_11 PF17123.5 CRK12999.1 - 2 8.2 4.0 4.4 7.1 4.0 1.6 1 0 0 1 1 1 0 RING-like zinc finger Chorismate_synt PF01264.21 CRK13000.1 - 5.3e-10 38.5 0.0 6.2e-10 38.3 0.0 1.1 1 0 0 1 1 1 1 Chorismate synthase Pkinase PF00069.25 CRK13004.1 - 4.4e-49 167.2 0.0 2.1e-32 112.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CRK13004.1 - 1.4e-21 77.0 0.0 7.1e-20 71.4 0.0 3.0 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CRK13004.1 - 0.00029 20.3 0.0 0.00099 18.5 0.0 1.8 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 CRK13004.1 - 0.0068 16.4 0.1 0.019 14.9 0.1 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CRK13004.1 - 0.0084 14.9 0.0 0.018 13.8 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Mucin PF01456.17 CRK13005.1 - 0.038 14.0 2.5 0.095 12.7 2.5 1.7 1 0 0 1 1 1 0 Mucin-like glycoprotein DJ-1_PfpI PF01965.24 CRK13006.1 - 9.6e-10 38.5 0.0 1.3e-09 38.1 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family AAA_33 PF13671.6 CRK13007.1 - 9e-14 51.8 0.1 1.3e-13 51.4 0.1 1.3 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 CRK13007.1 - 5.6e-10 38.8 0.0 8.3e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.6 CRK13007.1 - 1.7e-05 25.4 0.0 3.1e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 CRK13007.1 - 0.00017 21.8 0.1 0.00029 21.1 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CRK13007.1 - 0.001 19.5 0.1 0.0013 19.1 0.1 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.6 CRK13007.1 - 0.0033 17.8 0.0 0.006 17.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain CoaE PF01121.20 CRK13007.1 - 0.0067 16.1 0.0 0.0092 15.7 0.0 1.2 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA PF00004.29 CRK13007.1 - 0.0073 16.7 0.0 0.016 15.6 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 CRK13007.1 - 0.0093 16.5 0.0 0.01 16.3 0.0 1.3 1 1 0 1 1 1 1 ABC transporter SKI PF01202.22 CRK13007.1 - 0.011 15.9 0.0 0.025 14.7 0.0 1.6 1 0 0 1 1 1 0 Shikimate kinase Cytidylate_kin2 PF13189.6 CRK13007.1 - 0.015 15.5 0.1 0.11 12.6 0.0 2.2 2 0 0 2 2 2 0 Cytidylate kinase-like family AAA_22 PF13401.6 CRK13007.1 - 0.016 15.5 0.0 0.024 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 CRK13007.1 - 0.024 14.6 0.0 0.045 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.18 CRK13007.1 - 0.037 13.8 0.0 0.057 13.2 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase APS_kinase PF01583.20 CRK13007.1 - 0.05 13.5 0.0 0.069 13.0 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase NB-ARC PF00931.22 CRK13007.1 - 0.053 12.7 0.0 0.068 12.3 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Ploopntkinase3 PF18751.1 CRK13007.1 - 0.058 13.3 0.0 0.11 12.5 0.0 1.4 1 1 0 1 1 1 0 P-loop Nucleotide Kinase3 dNK PF01712.19 CRK13007.1 - 0.063 13.1 0.0 0.097 12.5 0.0 1.3 1 0 0 1 1 1 0 Deoxynucleoside kinase AAA_24 PF13479.6 CRK13007.1 - 0.069 12.9 0.1 0.17 11.6 0.0 1.7 2 1 0 2 2 1 0 AAA domain RNA_helicase PF00910.22 CRK13007.1 - 0.085 13.2 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Cytidylate_kin PF02224.18 CRK13007.1 - 0.089 12.5 0.1 0.16 11.7 0.1 1.4 1 0 0 1 1 1 0 Cytidylate kinase KTI12 PF08433.10 CRK13007.1 - 0.11 11.9 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Pkinase PF00069.25 CRK13009.1 - 6.3e-49 166.7 0.0 2.5e-32 112.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CRK13009.1 - 1.9e-21 76.5 0.0 1e-19 70.9 0.0 3.1 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CRK13009.1 - 0.0003 20.2 0.0 0.0011 18.4 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CRK13009.1 - 0.0064 15.3 0.1 0.016 14.0 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 CRK13009.1 - 0.0066 16.4 0.1 0.016 15.2 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family AAA_33 PF13671.6 CRK13012.1 - 9.3e-13 48.5 0.1 1.3e-12 48.1 0.1 1.3 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 CRK13012.1 - 2.8e-09 36.5 0.1 4.6e-09 35.9 0.1 1.4 1 1 0 1 1 1 1 Zeta toxin AAA_18 PF13238.6 CRK13012.1 - 0.00086 19.9 0.0 0.0022 18.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 CRK13012.1 - 0.049 14.1 0.0 0.095 13.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain Podoplanin PF05808.11 CRK13014.1 - 0.0013 18.8 2.5 0.0035 17.5 2.5 1.7 1 0 0 1 1 1 1 Podoplanin Fungal_trans_2 PF11951.8 CRK13015.1 - 4.7e-32 111.3 0.0 7.3e-32 110.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK13015.1 - 1.5e-07 31.4 14.8 2.4e-07 30.8 14.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC_tran_CTD PF16326.5 CRK13015.1 - 0.02 15.1 0.2 0.042 14.1 0.2 1.5 1 0 0 1 1 1 0 ABC transporter C-terminal domain Podoplanin PF05808.11 CRK13016.1 - 0.0014 18.7 2.4 0.0014 18.7 2.4 2.0 2 0 0 2 2 2 1 Podoplanin CYYR1 PF10873.8 CRK13016.1 - 0.23 11.9 0.1 0.23 11.9 0.1 2.0 2 0 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 DUF4834 PF16118.5 CRK13016.1 - 2.5 9.1 4.5 5.9 7.9 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) SKG6 PF08693.10 CRK13016.1 - 4.5 6.8 11.8 36 3.9 0.0 2.4 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Fungal_trans PF04082.18 CRK13018.1 - 6e-23 81.2 0.0 2.8e-21 75.8 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK13018.1 - 3.6e-09 36.6 9.1 6.5e-09 35.8 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mito_carr PF00153.27 CRK13019.1 - 5.9e-43 144.7 8.2 1e-17 63.8 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.27 CRK13021.1 - 2.9e-41 139.3 8.0 7.9e-17 61.0 0.1 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein Fungal_trans PF04082.18 CRK13021.1 - 2e-22 79.5 0.0 5.2e-21 74.9 0.0 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK13021.1 - 5.2e-09 36.1 9.1 8.8e-09 35.3 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SDA1 PF05285.12 CRK13022.1 - 1.8e-90 303.9 48.6 1.8e-90 303.9 48.6 2.7 2 1 0 2 2 2 1 SDA1 NUC130_3NT PF08158.12 CRK13022.1 - 4.6e-22 78.1 0.1 1e-21 77.0 0.1 1.6 1 0 0 1 1 1 1 NUC130/3NT domain Dict-STAT-coil PF09267.10 CRK13022.1 - 0.038 14.4 2.3 0.17 12.3 0.1 2.8 2 0 0 2 2 2 0 Dictyostelium STAT, coiled coil Glyco_hydro_61 PF03443.14 CRK13023.1 - 2.3e-60 204.0 0.0 3.3e-60 203.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 ECH_1 PF00378.20 CRK13024.1 - 7.1e-12 45.2 0.0 6.5e-09 35.5 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CRK13024.1 - 1.3e-07 31.5 0.0 4.5e-07 29.7 0.0 1.6 1 1 0 2 2 2 1 Enoyl-CoA hydratase/isomerase AAA_lid_7 PF17867.1 CRK13024.1 - 0.13 12.5 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 Midasin AAA lid domain Aldedh PF00171.22 CRK13025.1 - 9e-39 133.2 0.0 9.9e-39 133.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DnaJ PF00226.31 CRK13032.1 - 1.2e-11 44.5 1.8 2e-11 43.9 1.8 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CRK13032.1 - 0.0041 17.5 6.8 0.0072 16.7 6.8 1.4 1 0 0 1 1 1 1 DnaJ central domain AAA_11 PF13086.6 CRK13032.1 - 0.092 12.5 0.3 1.9 8.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain TPR_2 PF07719.17 CRK13032.1 - 0.22 11.7 1.0 0.6 10.4 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat UNC45-central PF11701.8 CRK13034.1 - 3.9e-09 36.7 0.0 4.7e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Myosin-binding striated muscle assembly central FA_hydroxylase PF04116.13 CRK13036.1 - 8.4e-18 65.0 9.7 1.1e-17 64.6 9.7 1.1 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily FGGY_C PF02782.16 CRK13044.1 - 9.4e-20 71.2 0.8 1.3e-19 70.8 0.8 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain GPI-anchored PF10342.9 CRK13074.1 - 6.8e-16 58.8 0.2 6.8e-16 58.8 0.2 2.5 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family BAT2_N PF07001.11 CRK13074.1 - 0.62 10.5 14.8 0.9 10.0 14.8 1.2 1 0 0 1 1 1 0 BAT2 N-terminus RNA_pol_Rpc4 PF05132.14 CRK13074.1 - 0.83 10.1 6.6 29 5.1 6.6 2.1 1 1 1 2 2 2 0 RNA polymerase III RPC4 DUF1180 PF06679.12 CRK13074.1 - 5.9 7.3 11.0 9.5 6.6 11.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) SpoIIE PF07228.12 CRK13075.1 - 1.4e-09 38.2 0.1 3.1e-09 37.0 0.0 1.6 1 1 1 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 CRK13075.1 - 1.1e-08 35.0 1.6 1.4e-08 34.6 0.5 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 CRK13075.1 - 3e-05 23.8 0.5 0.15 11.7 0.1 2.5 2 1 0 2 2 2 2 Protein phosphatase 2C PH_TFIIH PF08567.11 CRK13075.1 - 0.21 11.9 0.6 5.8 7.3 0.0 2.6 3 0 0 3 3 3 0 TFIIH p62 subunit, N-terminal domain Fer2_3 PF13085.6 CRK13076.1 - 1.6e-23 82.8 0.2 2.8e-23 82.0 0.2 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 CRK13076.1 - 1.4e-08 35.2 5.8 1.4e-08 35.2 5.8 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 CRK13076.1 - 6.1e-08 32.7 2.5 6.1e-08 32.7 2.5 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 CRK13076.1 - 7.8e-08 32.6 7.3 7.8e-08 32.6 7.3 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 CRK13076.1 - 0.00037 21.0 3.5 0.00037 21.0 3.5 2.4 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 CRK13076.1 - 0.011 15.7 1.4 0.011 15.7 1.4 3.0 3 1 1 4 4 4 0 2Fe-2S iron-sulfur cluster binding domain SF3a60_bindingd PF12108.8 CRK13076.1 - 0.12 12.3 0.4 0.19 11.6 0.4 1.3 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain Fer4_9 PF13187.6 CRK13076.1 - 1.1 9.5 14.5 0.91 9.7 9.5 2.9 2 1 1 3 3 3 0 4Fe-4S dicluster domain Dus PF01207.17 CRK13077.1 - 3.1e-10 39.6 0.0 1.1e-06 28.0 0.0 2.2 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) Fer2_3 PF13085.6 CRK13078.1 - 1.6e-16 60.3 0.0 2.2e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain BBE PF08031.12 CRK13078.1 - 0.12 12.5 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 Berberine and berberine like Zn_clus PF00172.18 CRK13079.1 - 7.5e-07 29.2 8.1 1.3e-06 28.4 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ATP-grasp PF02222.22 CRK13080.1 - 8.3e-50 168.7 0.0 1.3e-49 168.0 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain AIRC PF00731.20 CRK13080.1 - 1e-40 138.7 0.1 3.2e-40 137.1 0.1 1.9 1 0 0 1 1 1 1 AIR carboxylase PurK_C PF17769.1 CRK13080.1 - 4.3e-12 45.5 0.0 8.9e-12 44.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 CRK13080.1 - 2.4e-06 27.2 0.0 6e-06 25.9 0.0 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus XdhC_C PF13478.6 CRK13080.1 - 0.0012 19.4 0.1 1.8 9.1 0.0 2.5 2 0 0 2 2 2 2 XdhC Rossmann domain PrpR_N PF06506.11 CRK13080.1 - 0.16 11.5 0.2 1.5 8.4 0.0 2.2 2 0 0 2 2 2 0 Propionate catabolism activator Toxin_30 PF08117.11 CRK13081.1 - 0.0021 18.3 2.1 1.9 8.8 0.5 3.1 2 0 0 2 2 2 2 Ptu family HCBP_related PF06594.11 CRK13082.1 - 0.0057 16.6 0.2 3.4 7.7 0.0 2.4 2 0 0 2 2 2 2 Haemolysin-type calcium binding protein related domain Chromo_2 PF18704.1 CRK13082.1 - 0.047 14.0 1.1 11 6.4 0.0 3.2 3 0 0 3 3 3 0 Chromatin organization modifier domain 2 Cyclin_N PF00134.23 CRK13083.1 - 8.7e-11 41.7 0.1 3.1e-10 39.9 0.1 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.19 CRK13083.1 - 0.06 13.4 0.1 0.34 11.0 0.1 2.1 2 0 0 2 2 2 0 Transcription factor TFIIB repeat WD40 PF00400.32 CRK13084.1 - 5.9e-50 166.2 29.9 1.6e-08 35.1 1.8 10.1 10 1 0 10 10 10 7 WD domain, G-beta repeat PRP4 PF08799.11 CRK13084.1 - 1.5e-30 104.4 15.1 4.2e-15 55.0 3.7 2.4 2 0 0 2 2 2 2 pre-mRNA processing factor 4 (PRP4) like ANAPC4_WD40 PF12894.7 CRK13084.1 - 6.8e-20 71.2 2.3 0.11 12.8 0.0 8.5 5 3 3 8 8 8 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CRK13084.1 - 9.4e-05 21.5 0.0 73 2.2 0.0 6.4 3 2 5 8 8 8 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 CRK13084.1 - 0.00038 19.9 0.0 5.2 6.3 0.0 3.6 3 0 0 3 3 3 2 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 CRK13084.1 - 0.014 14.8 0.0 4.8 6.4 0.0 3.6 4 0 0 4 4 4 0 WD40-like domain Lactonase PF10282.9 CRK13084.1 - 0.056 12.7 0.0 46 3.1 0.0 4.0 5 0 0 5 5 5 0 Lactonase, 7-bladed beta-propeller DHR10 PF18595.1 CRK13084.1 - 0.068 13.2 0.6 16 5.6 0.1 2.4 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain cNMPbd_u2 PF16643.5 CRK13084.1 - 0.14 12.6 0.2 29 5.1 0.0 2.3 2 0 0 2 2 2 0 Unstructured region on cNMP-binding protein Pkinase PF00069.25 CRK13085.1 - 4.6e-68 229.4 0.0 5.7e-68 229.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK13085.1 - 1.8e-32 112.6 0.0 2.4e-32 112.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CRK13085.1 - 0.0038 16.2 0.1 0.0054 15.7 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_C PF00433.24 CRK13085.1 - 0.014 16.1 0.4 0.044 14.5 0.4 1.9 1 0 0 1 1 1 0 Protein kinase C terminal domain Pkinase_fungal PF17667.1 CRK13085.1 - 0.09 11.5 0.0 0.21 10.4 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase Kinase-like PF14531.6 CRK13085.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.4 1 1 0 1 1 1 0 Kinase-like Pkinase PF00069.25 CRK13087.1 - 1.1e-67 228.2 0.0 1.5e-67 227.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain CDH-cyt PF16010.5 CRK13087.1 - 4.9e-53 179.5 11.8 2.5e-26 92.5 1.9 2.3 2 0 0 2 2 2 2 Cytochrome domain of cellobiose dehydrogenase Pkinase_Tyr PF07714.17 CRK13087.1 - 4.6e-32 111.3 0.0 6.5e-32 110.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DOMON PF03351.17 CRK13087.1 - 1.1e-10 41.9 1.9 0.00045 20.4 0.1 2.4 2 0 0 2 2 2 2 DOMON domain DUF2427 PF10348.9 CRK13087.1 - 4.1e-06 26.5 22.5 9.3e-06 25.4 8.7 3.4 3 0 0 3 3 3 2 Domain of unknown function (DUF2427) Haspin_kinase PF12330.8 CRK13087.1 - 0.014 14.4 0.1 0.022 13.7 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain DUF4148 PF13663.6 CRK13087.1 - 0.95 9.7 5.9 5.7 7.2 0.4 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4148) DUF4538 PF15061.6 CRK13087.1 - 5.8 6.7 9.4 25 4.7 1.5 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4538) ATP_sub_h PF10775.9 CRK13088.1 - 3e-25 88.0 0.9 3e-25 88.0 0.9 1.5 2 0 0 2 2 2 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.11 CRK13088.1 - 0.11 12.9 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 ATP_sub_h PF10775.9 CRK13089.1 - 3e-25 88.0 0.9 3e-25 88.0 0.9 1.5 2 0 0 2 2 2 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.11 CRK13089.1 - 0.11 12.9 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 Pkinase PF00069.25 CRK13090.1 - 8e-41 140.1 0.0 1.1e-40 139.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK13090.1 - 1.4e-20 73.6 0.0 2.1e-20 73.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CRK13090.1 - 2.4e-07 30.4 0.0 3.6e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CRK13090.1 - 0.00073 18.6 0.0 0.0011 18.0 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CRK13090.1 - 0.044 13.7 0.1 0.089 12.7 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 CRK13090.1 - 0.049 13.0 0.1 0.078 12.3 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family C2 PF00168.30 CRK13091.1 - 1.6e-08 34.8 0.0 7.2e-05 23.0 0.0 2.5 2 0 0 2 2 2 2 C2 domain SUZ PF12752.7 CRK13092.1 - 0.00033 21.4 8.0 0.00033 21.4 8.0 4.5 4 2 0 4 4 4 1 SUZ domain SUZ-C PF12901.7 CRK13092.1 - 0.0061 16.5 1.7 0.02 14.9 1.7 1.8 1 0 0 1 1 1 1 SUZ-C motif XAP5 PF04921.14 CRK13092.1 - 0.83 9.4 4.2 0.44 10.3 0.3 1.9 2 0 0 2 2 2 0 XAP5, circadian clock regulator Tom5 PF10642.9 CRK13092.1 - 8.1 6.6 9.1 6.1 7.0 0.7 3.0 2 1 1 3 3 3 0 Mitochondrial import receptor subunit or translocase eIF3_subunit PF08597.10 CRK13092.1 - 9.7 6.0 13.6 5 7.0 4.7 2.1 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit Fe_hyd_lg_C PF02906.14 CRK13093.1 - 1.4e-51 175.6 0.0 4.3e-51 173.9 0.0 1.9 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain zf-H2C2_2 PF13465.6 CRK13095.1 - 3.8e-06 27.1 1.1 3.8e-06 27.1 1.1 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 CRK13095.1 - 2.9e-05 24.3 0.3 2.9e-05 24.3 0.3 3.7 3 1 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 CRK13095.1 - 3.2e-05 23.8 0.5 0.071 13.1 0.0 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger Trypan_PARP PF05887.11 CRK13095.1 - 0.0002 21.3 15.3 0.00042 20.3 15.3 1.5 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) FOXP-CC PF16159.5 CRK13095.1 - 0.00027 21.5 11.4 0.18 12.5 0.0 3.7 3 1 1 4 4 4 2 FOXP coiled-coil domain SPX PF03105.19 CRK13095.1 - 0.00074 19.5 6.1 0.0011 19.0 6.1 1.2 1 0 0 1 1 1 1 SPX domain zf-C2H2_4 PF13894.6 CRK13095.1 - 0.002 18.8 6.7 0.014 16.2 0.3 3.2 3 0 0 3 3 3 1 C2H2-type zinc finger DUF5595 PF18077.1 CRK13095.1 - 0.058 13.5 0.3 0.16 12.0 0.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5595) ADH_zinc_N_2 PF13602.6 CRK13096.1 - 6.4e-16 59.6 0.0 1.3e-15 58.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 CRK13096.1 - 2.4e-10 40.5 0.0 4.2e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PASTA PF03793.19 CRK13096.1 - 0.006 16.4 0.0 0.015 15.1 0.0 1.7 1 0 0 1 1 1 1 PASTA domain Glu_dehyd_C PF16912.5 CRK13096.1 - 0.16 11.5 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Glyco_hydro_18 PF00704.28 CRK13098.1 - 1.7e-83 281.0 3.1 2.1e-83 280.7 3.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Cuticle_2 PF08184.11 CRK13098.1 - 0.061 13.3 0.4 0.18 11.8 0.4 1.8 1 0 0 1 1 1 0 Cuticle protein 7 isoform family DUF963 PF06131.11 CRK13099.1 - 0.0044 16.4 6.2 0.0044 16.4 6.2 3.6 3 1 1 4 4 4 2 Schizosaccharomyces pombe repeat of unknown function (DUF963) Presenilin PF01080.17 CRK13099.1 - 0.17 10.6 8.8 0.27 10.0 8.8 1.3 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 CRK13099.1 - 6.7 4.7 8.2 8.8 4.3 8.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein 6PGD PF00393.19 CRK13100.1 - 2.2e-21 76.5 0.0 2.8e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain EamA PF00892.20 CRK13100.1 - 0.0009 19.4 6.1 0.0017 18.5 6.1 1.6 1 1 0 1 1 1 1 EamA-like transporter family TPT PF03151.16 CRK13100.1 - 0.0013 18.2 0.1 0.0017 17.7 0.1 1.3 1 0 0 1 1 1 1 Triose-phosphate Transporter family PUNUT PF16913.5 CRK13100.1 - 0.0086 15.3 0.2 0.011 15.0 0.2 1.1 1 0 0 1 1 1 1 Purine nucleobase transmembrane transport HELP PF03451.14 CRK13100.1 - 0.17 11.8 0.0 0.93 9.4 0.0 2.1 2 0 0 2 2 2 0 HELP motif RRM_1 PF00076.22 CRK13101.1 - 3.9e-21 74.7 0.0 9.4e-17 60.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cytotoxic PF09000.10 CRK13101.1 - 1.6e-07 31.6 0.2 0.014 15.7 0.1 2.6 2 0 0 2 2 2 2 Cytotoxic Polyketide_cyc2 PF10604.9 CRK13101.1 - 0.0017 18.6 0.3 2.7 8.2 0.0 2.7 2 0 0 2 2 2 2 Polyketide cyclase / dehydrase and lipid transport RRM_7 PF16367.5 CRK13101.1 - 0.02 15.0 0.0 5.2 7.3 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif CHASE6_C PF17150.4 CRK13101.1 - 0.18 12.5 0.0 43 4.9 0.0 2.4 2 0 0 2 2 2 0 C-terminal domain of two-partite extracellular sensor domain TPT PF03151.16 CRK13103.1 - 4e-20 72.3 13.1 6.1e-20 71.7 13.1 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CRK13103.1 - 3.7e-06 27.2 33.5 0.0062 16.7 6.7 2.5 2 1 0 2 2 2 2 EamA-like transporter family PUNUT PF16913.5 CRK13103.1 - 0.0031 16.8 12.9 0.0074 15.5 12.9 1.7 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport UAA PF08449.11 CRK13103.1 - 0.0076 15.5 15.3 0.012 14.8 15.3 1.3 1 0 0 1 1 1 1 UAA transporter family SLATT_1 PF18181.1 CRK13103.1 - 0.23 11.4 6.4 3.3 7.7 0.5 2.4 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 PBP1_TM PF14812.6 CRK13103.1 - 1.8 9.0 7.7 0.38 11.1 3.5 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Glyco_hydro_15 PF00723.21 CRK13104.1 - 9.2e-53 179.6 0.0 9.7e-51 172.9 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 Peptidase_S9 PF00326.21 CRK13105.1 - 3.7e-53 180.1 0.0 7.3e-53 179.2 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Bromo_TP PF07524.13 CRK13105.1 - 6e-13 48.6 0.0 3e-06 27.1 0.0 2.6 2 0 0 2 2 2 2 Bromodomain associated TFIID-31kDa PF02291.15 CRK13105.1 - 5.8e-06 26.4 0.0 0.067 13.3 0.0 2.3 2 0 0 2 2 2 2 Transcription initiation factor IID, 31kD subunit Abhydrolase_1 PF00561.20 CRK13105.1 - 7.5e-05 22.5 0.6 0.001 18.8 0.4 2.4 1 1 1 2 2 2 1 alpha/beta hydrolase fold PD40 PF07676.12 CRK13105.1 - 8.3e-05 22.4 0.0 0.15 12.0 0.0 3.0 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat AXE1 PF05448.12 CRK13105.1 - 0.075 11.7 0.1 2.1 6.9 0.1 2.1 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) NuA4 PF09340.10 CRK13107.1 - 1.3e-22 79.5 0.2 1.3e-22 79.5 0.2 1.7 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 Glyco_hydro_61 PF03443.14 CRK13109.1 - 1e-49 169.3 0.0 1.2e-49 169.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Fungal_trans PF04082.18 CRK13110.1 - 3.5e-11 42.7 0.1 6e-11 41.9 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glutaredoxin PF00462.24 CRK13111.1 - 2.4e-10 40.5 0.0 3.8e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin RRM_1 PF00076.22 CRK13112.1 - 3.9e-17 61.8 0.0 6.1e-17 61.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cytotoxic PF09000.10 CRK13112.1 - 0.0038 17.5 0.1 0.0098 16.2 0.1 1.7 1 0 0 1 1 1 1 Cytotoxic PBP1_TM PF14812.6 CRK13113.1 - 0.0071 16.7 1.1 0.0071 16.7 1.1 2.1 2 0 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Baculo_PEP_C PF04513.12 CRK13113.1 - 0.019 15.0 0.6 0.041 13.9 0.6 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 CRK13113.1 - 0.022 14.8 1.3 0.045 13.8 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Sipho_Gp157 PF05565.11 CRK13113.1 - 0.023 14.7 0.1 0.051 13.6 0.1 1.5 1 0 0 1 1 1 0 Siphovirus Gp157 TRPM_tetra PF16519.5 CRK13113.1 - 0.065 13.4 1.4 0.16 12.1 1.4 1.6 1 0 0 1 1 1 0 Tetramerisation domain of TRPM NPV_P10 PF05531.12 CRK13113.1 - 0.14 12.7 2.3 0.31 11.5 2.3 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.9 CRK13113.1 - 0.16 12.3 0.3 0.33 11.3 0.3 1.5 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 WASH_WAHD PF11945.8 CRK13113.1 - 0.19 11.3 3.3 0.35 10.4 3.3 1.3 1 0 0 1 1 1 0 WAHD domain of WASH complex Glyco_hydro_15 PF00723.21 CRK13114.1 - 2e-53 181.8 0.0 2.2e-51 175.1 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 Peptidase_S9 PF00326.21 CRK13115.1 - 1e-25 90.4 0.0 2.2e-25 89.4 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Bromo_TP PF07524.13 CRK13115.1 - 5.5e-06 26.3 0.0 1.1e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated PD40 PF07676.12 CRK13115.1 - 0.00039 20.3 0.0 0.12 12.3 0.0 3.0 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat TFIID-31kDa PF02291.15 CRK13115.1 - 0.023 14.7 0.0 0.047 13.8 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit NuA4 PF09340.10 CRK13117.1 - 1.2e-22 79.6 0.2 1.2e-22 79.6 0.2 1.8 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 Glyco_hydro_61 PF03443.14 CRK13120.1 - 1.1e-49 169.2 0.0 1.3e-49 168.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Fungal_trans PF04082.18 CRK13121.1 - 1.6e-12 47.0 0.1 3e-12 46.2 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glutaredoxin PF00462.24 CRK13122.1 - 1.5e-18 66.8 0.0 3.3e-17 62.4 0.0 2.3 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.20 CRK13122.1 - 2.9e-13 49.7 0.0 6.1e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin HyaE PF07449.11 CRK13122.1 - 0.0012 18.8 0.0 0.16 11.9 0.0 2.2 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE Thioredoxin_8 PF13905.6 CRK13122.1 - 0.0033 17.7 0.0 2.4 8.6 0.0 2.7 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.6 CRK13122.1 - 0.0073 16.8 0.0 0.11 13.0 0.0 2.6 2 2 0 2 2 2 1 Thioredoxin-like domain Disulph_isomer PF06491.11 CRK13122.1 - 0.11 12.6 0.2 23 5.1 0.0 2.7 2 1 1 3 3 3 0 Disulphide isomerase SAP130_C PF16014.5 CRK13122.1 - 0.55 9.3 3.1 0.72 8.9 3.1 1.3 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus SH3_9 PF14604.6 CRK13123.1 - 4.3e-28 96.9 3.3 4.7e-13 48.8 0.3 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 CRK13123.1 - 2.1e-26 91.2 4.8 7.4e-14 51.1 0.3 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 CRK13123.1 - 2.7e-17 62.2 0.2 8.7e-08 31.7 0.0 2.9 3 0 0 3 3 3 2 Variant SH3 domain Cofilin_ADF PF00241.20 CRK13123.1 - 5.5e-15 55.2 0.0 9.9e-15 54.4 0.0 1.4 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Neocarzinostat PF00960.18 CRK13123.1 - 0.0029 17.6 0.1 3.7 7.6 0.0 2.7 2 0 0 2 2 2 2 Neocarzinostatin family CYLD_phos_site PF16607.5 CRK13123.1 - 0.13 12.1 3.7 6.9 6.5 0.3 2.5 2 0 0 2 2 2 0 Phosphorylation region of CYLD, unstructured APC_u15 PF16636.5 CRK13123.1 - 5 7.6 10.1 7 7.2 0.5 3.3 3 0 0 3 3 3 0 Unstructured region on APC between APC_crr regions 5 and 6 CYSTM PF12734.7 CRK13124.1 - 2.1e-05 24.7 40.1 2.1e-05 24.7 40.1 4.8 1 1 2 3 3 3 1 Cysteine-rich TM module stress tolerance Arrestin_N PF00339.29 CRK13125.1 - 3.1e-16 59.8 0.0 7.3e-16 58.5 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 CRK13125.1 - 1.8e-05 25.2 0.0 0.0057 17.1 0.0 2.6 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain AAA_22 PF13401.6 CRK13126.1 - 1.2e-14 54.7 0.2 5.4e-14 52.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CRK13126.1 - 1.2e-12 48.6 0.1 3.3e-11 43.9 0.1 2.9 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 CRK13126.1 - 5e-12 46.4 0.0 1.8e-11 44.6 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_10 PF17872.1 CRK13126.1 - 2.9e-07 30.5 0.2 6.7e-07 29.4 0.0 1.7 2 0 0 2 2 1 1 AAA lid domain TniB PF05621.11 CRK13126.1 - 1.3e-05 24.7 0.0 2.8e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Bacterial TniB protein Cdc6_C PF09079.11 CRK13126.1 - 1.5e-05 24.8 0.5 9.9e-05 22.2 0.1 2.6 2 1 0 2 2 1 1 CDC6, C terminal winged helix domain AAA_19 PF13245.6 CRK13126.1 - 2.4e-05 24.7 0.1 8.2e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CRK13126.1 - 0.00068 19.4 0.0 0.0018 18.0 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_5 PF07728.14 CRK13126.1 - 0.0023 17.9 0.0 0.0063 16.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 CRK13126.1 - 0.0024 17.4 0.0 0.0047 16.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region DUF815 PF05673.13 CRK13126.1 - 0.0024 17.1 0.0 0.0048 16.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Rad17 PF03215.15 CRK13126.1 - 0.0034 17.3 0.0 0.006 16.5 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain SseB_C PF14581.6 CRK13126.1 - 0.0037 17.3 0.0 0.018 15.2 0.0 2.1 2 0 0 2 2 2 1 SseB protein C-terminal domain AAA_18 PF13238.6 CRK13126.1 - 0.0039 17.7 0.0 0.01 16.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 CRK13126.1 - 0.0058 15.9 0.0 0.013 14.8 0.0 1.6 1 1 0 1 1 1 1 KAP family P-loop domain RNA_helicase PF00910.22 CRK13126.1 - 0.006 17.0 0.0 0.013 15.8 0.0 1.6 1 0 0 1 1 1 1 RNA helicase ATPase_2 PF01637.18 CRK13126.1 - 0.012 15.6 0.0 0.031 14.2 0.0 1.7 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 CRK13126.1 - 0.017 14.9 0.0 0.034 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 CRK13126.1 - 0.031 14.1 0.1 0.1 12.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 CRK13126.1 - 0.036 13.2 0.1 0.11 11.6 0.0 1.8 2 1 1 3 3 3 0 NB-ARC domain NTPase_1 PF03266.15 CRK13126.1 - 0.045 13.7 0.4 0.096 12.6 0.0 1.7 2 0 0 2 2 1 0 NTPase AAA_14 PF13173.6 CRK13126.1 - 0.054 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 CRK13126.1 - 0.097 12.0 0.1 1.2 8.5 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 CRK13126.1 - 0.14 12.4 0.8 3.2 8.0 0.1 2.4 2 0 0 2 2 2 0 AAA domain TPR_12 PF13424.6 CRK13126.1 - 0.26 11.6 1.7 0.39 11.0 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat MCLC PF05934.11 CRK13126.1 - 0.32 9.7 0.8 0.47 9.1 0.8 1.1 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) Minor_tail_Z PF06763.11 CRK13126.1 - 0.56 10.0 3.5 0.39 10.5 1.1 1.8 2 0 0 2 2 2 0 Prophage minor tail protein Z (GPZ) MOSC_N PF03476.16 CRK13127.1 - 6.7e-24 84.1 0.0 1.3e-23 83.2 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Aminotran_5 PF00266.19 CRK13127.1 - 1.2e-19 70.5 0.0 1.9e-19 69.9 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-V PGM_PMM_IV PF00408.20 CRK13127.1 - 0.019 15.2 0.0 0.043 14.0 0.0 1.5 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, C-terminal domain MOSC PF03473.17 CRK13127.1 - 0.11 12.5 0.0 0.31 11.1 0.0 1.8 2 0 0 2 2 2 0 MOSC domain Baculo_PEP_C PF04513.12 CRK13130.1 - 0.002 18.2 0.0 1.5 8.9 0.0 2.5 2 0 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF962 PF06127.11 CRK13133.1 - 4.2e-27 94.1 0.1 8.3e-27 93.1 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF962) SHS2_Rpb7-N PF03876.17 CRK13134.1 - 9.2e-15 54.8 0.0 1.5e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 CRK13134.1 - 2.5e-11 43.8 0.0 3.9e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 S1 RNA binding domain DUF836 PF05768.14 CRK13136.1 - 1.5e-12 47.8 0.0 1.8e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 CRK13136.1 - 0.00019 21.6 0.0 0.00048 20.3 0.0 1.6 2 0 0 2 2 2 1 Glutaredoxin DUF1223 PF06764.11 CRK13136.1 - 0.11 12.5 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1223) CHORD PF04968.12 CRK13137.1 - 9.4e-48 160.8 18.4 4.6e-25 88.1 5.4 2.2 2 0 0 2 2 2 2 CHORD CS PF04969.16 CRK13137.1 - 5.6e-12 46.5 0.0 9e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 CS domain Cyt_bd_oxida_II PF02322.15 CRK13139.1 - 0.0017 17.8 0.8 0.0028 17.1 0.8 1.3 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit II Saf_2TM PF18303.1 CRK13139.1 - 0.14 11.7 3.6 6.7 6.3 0.2 3.0 2 1 1 3 3 3 0 SAVED-fused 2TM effector domain WH2 PF02205.20 CRK13140.1 - 5.9e-07 29.1 0.8 5.9e-07 29.1 0.8 1.8 2 0 0 2 2 2 1 WH2 motif RRM_1 PF00076.22 CRK13141.1 - 2.2e-37 126.7 0.0 5.4e-19 67.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CRK13141.1 - 0.029 14.5 0.0 1.7 8.8 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif SET_assoc PF11767.8 CRK13141.1 - 0.067 12.8 0.0 7.4 6.3 0.0 2.5 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated TFIIF_alpha PF05793.12 CRK13141.1 - 0.96 8.0 73.4 1.7 7.2 73.4 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Ribosomal_L37 PF08561.10 CRK13142.1 - 1.2e-37 129.1 0.3 2.1e-37 128.3 0.3 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 CHD5 PF04420.14 CRK13142.1 - 0.2 11.5 0.4 0.37 10.6 0.4 1.3 1 0 0 1 1 1 0 CHD5-like protein DUF4094 PF13334.6 CRK13143.1 - 0.067 13.6 0.9 0.16 12.4 0.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) DUF3347 PF11827.8 CRK13143.1 - 1 9.5 7.2 0.18 12.0 3.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3347) Ribosomal_S17e PF00833.18 CRK13144.1 - 0.0074 16.2 2.5 0.0088 16.0 2.5 1.2 1 0 0 1 1 1 1 Ribosomal S17 EB1 PF03271.17 CRK13144.1 - 0.02 15.1 0.2 2 8.7 0.6 2.3 2 0 0 2 2 2 0 EB1-like C-terminal motif DUF3138 PF11336.8 CRK13144.1 - 0.031 12.9 2.1 0.032 12.9 2.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Gasdermin_C PF17708.1 CRK13144.1 - 0.034 14.2 0.2 0.039 14.1 0.2 1.1 1 0 0 1 1 1 0 Gasdermin PUB domain Ribosomal_60s PF00428.19 CRK13144.1 - 0.23 12.1 8.6 0.22 12.2 8.0 1.3 1 1 0 1 1 1 0 60s Acidic ribosomal protein DUF3074 PF11274.8 CRK13145.1 - 5.6e-40 137.3 1.7 1e-39 136.4 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3074) AIP3 PF03915.13 CRK13145.1 - 0.00046 19.4 1.5 0.00075 18.7 1.5 1.2 1 0 0 1 1 1 1 Actin interacting protein 3 STAT_alpha PF01017.20 CRK13145.1 - 0.0024 17.8 4.3 0.0044 16.9 4.3 1.4 1 0 0 1 1 1 1 STAT protein, all-alpha domain AAA_13 PF13166.6 CRK13145.1 - 0.025 13.3 1.5 0.039 12.6 1.5 1.2 1 0 0 1 1 1 0 AAA domain Lectin_N PF03954.14 CRK13145.1 - 0.033 13.9 1.4 0.068 12.9 1.4 1.4 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain DUF948 PF06103.11 CRK13145.1 - 0.11 12.7 2.2 0.35 11.1 2.2 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Spc7 PF08317.11 CRK13145.1 - 0.25 10.2 8.1 0.4 9.5 8.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Baculo_p24 PF05073.12 CRK13145.1 - 0.32 10.8 0.9 0.55 10.0 0.9 1.3 1 0 0 1 1 1 0 Baculovirus P24 capsid protein BRE1 PF08647.11 CRK13145.1 - 1.8 8.7 7.5 0.53 10.4 2.2 2.3 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase NAD_binding_10 PF13460.6 CRK13146.1 - 3.1e-10 40.2 0.0 5.1e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 CRK13146.1 - 2.7e-08 33.7 0.0 3.8e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Glyco_transf_4 PF13439.6 CRK13146.1 - 0.0079 16.2 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 F420_oxidored PF03807.17 CRK13146.1 - 0.013 16.0 0.1 4.5 7.9 0.0 2.4 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 CRK13146.1 - 0.026 14.6 0.0 1.5 8.9 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase PI-PLC-Y PF00387.19 CRK13147.1 - 1.1e-37 128.9 0.0 1.9e-37 128.1 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain Kinesin PF00225.23 CRK13148.1 - 4.9e-117 390.6 0.3 1.9e-94 316.3 0.1 4.1 5 0 0 5 5 5 2 Kinesin motor domain Microtub_bd PF16796.5 CRK13148.1 - 5.4e-36 123.8 0.0 1.5e-19 70.4 0.0 3.1 3 0 0 3 3 3 2 Microtubule binding CCDC32 PF14989.6 CRK13148.1 - 3.8e-05 23.7 0.0 0.59 10.1 0.0 2.9 2 0 0 2 2 2 2 Coiled-coil domain containing 32 AAA_30 PF13604.6 CRK13148.1 - 0.00096 18.9 1.9 1.5 8.5 0.1 2.9 2 0 0 2 2 2 2 AAA domain PIF1 PF05970.14 CRK13148.1 - 0.0027 16.9 1.0 1.9 7.6 0.1 2.4 2 0 0 2 2 2 2 PIF1-like helicase DapH_N PF08503.10 CRK13148.1 - 0.06 13.6 0.0 24 5.3 0.0 2.6 2 0 0 2 2 2 0 Tetrahydrodipicolinate succinyltransferase N-terminal TsaE PF02367.17 CRK13148.1 - 0.095 12.7 0.0 27 4.8 0.0 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PhoH PF02562.16 CRK13148.1 - 0.14 11.6 2.1 13 5.2 0.2 2.5 2 0 0 2 2 2 0 PhoH-like protein PRRSV_Env PF02340.15 CRK13148.1 - 0.15 11.4 0.0 16 4.8 0.0 2.3 2 0 0 2 2 2 0 PRRSV putative envelope protein DUF2407_C PF13373.6 CRK13148.1 - 0.18 12.0 7.9 5.7 7.1 1.0 3.1 2 0 0 2 2 2 0 DUF2407 C-terminal domain AAA_7 PF12775.7 CRK13148.1 - 0.18 11.3 0.6 22 4.5 0.1 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region ECSIT_C PF14784.6 CRK13148.1 - 0.24 11.8 5.4 24 5.3 0.0 3.9 4 0 0 4 4 4 0 C-terminal domain of the ECSIT protein gpW PF02831.15 CRK13148.1 - 0.24 11.3 4.6 12 5.9 0.4 2.8 2 0 0 2 2 2 0 gpW GBP_C PF02841.14 CRK13148.1 - 0.26 10.7 20.4 1.3 8.3 5.8 2.5 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain ALC PF17527.2 CRK13148.1 - 1.2 8.7 9.3 6.7 6.3 1.2 2.7 2 0 0 2 2 2 0 Phage ALC protein AAA_16 PF13191.6 CRK13148.1 - 1.3 9.3 9.9 6.3 7.1 0.0 4.1 4 0 0 4 4 3 0 AAA ATPase domain DUF4618 PF15397.6 CRK13148.1 - 1.7 8.0 17.2 6.1 6.2 4.7 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) Microtub_bind PF13931.6 CRK13148.1 - 8 6.9 11.2 25 5.2 2.0 3.0 2 0 0 2 2 2 0 Kinesin-associated microtubule-binding HCV_NS5a_C PF12941.7 CRK13149.1 - 0.05 13.4 0.7 0.23 11.3 0.5 2.1 2 0 0 2 2 2 0 HCV NS5a protein C-terminal region NAD_binding_10 PF13460.6 CRK13150.1 - 1.9e-10 41.0 0.0 3.5e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 CRK13150.1 - 1.6e-09 37.7 0.0 2.3e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family F420_oxidored PF03807.17 CRK13150.1 - 0.0059 17.2 0.1 5 7.8 0.0 3.0 3 0 0 3 3 3 2 NADP oxidoreductase coenzyme F420-dependent Glyco_transf_4 PF13439.6 CRK13150.1 - 0.0098 15.9 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Phosphodiest PF01663.22 CRK13154.1 - 1e-64 219.4 0.1 1.9e-64 218.5 0.1 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase SpoIIIAH PF12685.7 CRK13154.1 - 0.007 16.2 2.0 0.013 15.4 2.0 1.3 1 0 0 1 1 1 1 SpoIIIAH-like protein DUF1764 PF08576.10 CRK13154.1 - 0.32 11.9 1.6 0.71 10.8 1.6 1.5 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) SNF2_N PF00176.23 CRK13155.1 - 3.1e-55 187.3 2.3 1.2e-54 185.4 2.3 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CRK13155.1 - 1.2e-13 51.3 0.0 3.2e-13 50.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SPT6_acidic PF14632.6 CRK13155.1 - 2.5e-11 44.0 15.2 2.5e-05 24.8 2.4 3.2 2 0 0 2 2 2 2 Acidic N-terminal SPT6 ResIII PF04851.15 CRK13155.1 - 6.6e-08 32.7 0.0 1.9e-07 31.3 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 CRK13155.1 - 8.1e-08 32.0 5.4 9.4e-08 31.8 2.0 2.6 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CRK13155.1 - 9.3e-08 32.0 1.3 9.3e-08 32.0 1.3 2.7 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CRK13155.1 - 6.1e-07 29.2 1.6 6.1e-07 29.2 1.6 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CRK13155.1 - 1.5e-06 28.0 8.2 2.2e-06 27.4 4.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) AAA_34 PF13872.6 CRK13155.1 - 3.1e-06 26.3 0.0 7.4e-06 25.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 zf-RING_2 PF13639.6 CRK13155.1 - 0.00012 22.3 5.3 0.00012 22.3 5.3 2.6 2 1 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 CRK13155.1 - 0.00021 21.2 6.8 0.00037 20.4 4.3 2.4 2 0 0 2 2 2 1 zinc-RING finger domain YL1 PF05764.13 CRK13155.1 - 0.019 15.1 34.1 0.061 13.4 11.9 3.3 3 0 0 3 3 3 0 YL1 nuclear protein zf-C3HC4_4 PF15227.6 CRK13155.1 - 0.13 12.5 9.1 0.032 14.4 5.6 1.9 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING Nop53 PF07767.11 CRK13155.1 - 0.57 9.5 26.2 0.69 9.2 9.1 2.5 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) zf-P11 PF03854.14 CRK13155.1 - 0.62 9.8 4.1 19 5.0 0.2 3.3 3 0 0 3 3 3 0 P-11 zinc finger Stm1_N PF09598.10 CRK13155.1 - 0.69 10.8 17.3 4 8.3 4.1 2.9 2 0 0 2 2 2 0 Stm1 DMAP_binding PF06464.11 CRK13155.1 - 0.79 10.6 9.8 8.9 7.2 1.8 3.2 2 0 0 2 2 2 0 DMAP1-binding Domain Prok-RING_4 PF14447.6 CRK13155.1 - 1.8 8.5 6.8 8.8 6.3 7.0 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Nop14 PF04147.12 CRK13155.1 - 2.1 6.5 28.2 0.89 7.7 12.2 2.2 2 0 0 2 2 2 0 Nop14-like family zf-RING_4 PF14570.6 CRK13155.1 - 2.2 8.1 6.7 4.3 7.2 5.7 2.1 2 0 0 2 2 1 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 CRK13155.1 - 5.9 7.1 5.3 3.3 7.9 2.2 2.3 2 0 0 2 2 1 0 zinc RING finger of MSL2 Med17 PF10156.9 CRK13156.1 - 2.6e-88 296.8 0.0 3.3e-88 296.4 0.0 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex dsrm PF00035.26 CRK13156.1 - 0.81 10.4 2.5 0.67 10.7 0.5 1.9 2 0 0 2 2 2 0 Double-stranded RNA binding motif Med17 PF10156.9 CRK13158.1 - 6.3e-90 302.1 0.0 8e-90 301.8 0.0 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex PFK PF00365.20 CRK13159.1 - 1.3e-241 799.0 4.8 1.8e-97 326.1 0.6 3.3 2 1 1 3 3 3 3 Phosphofructokinase Unstab_antitox PF09720.10 CRK13159.1 - 0.038 14.0 0.3 2.9 8.0 0.1 2.7 2 0 0 2 2 2 0 Putative addiction module component TgMIC1 PF11476.8 CRK13159.1 - 0.078 12.7 3.0 30 4.4 0.0 3.5 3 0 0 3 3 3 0 Toxoplasma gondii micronemal protein 1 TgMIC1 HMG_CoA_synt_N PF01154.17 CRK13159.1 - 0.087 12.7 0.3 21 4.9 0.0 2.6 2 0 0 2 2 2 0 Hydroxymethylglutaryl-coenzyme A synthase N terminal DAGK_cat PF00781.24 CRK13159.1 - 0.089 12.4 0.1 0.35 10.5 0.1 2.1 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Saf_2TM PF18303.1 CRK13159.1 - 0.095 12.3 2.0 12 5.5 0.1 2.6 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain BDHCT PF08072.11 CRK13159.1 - 0.13 12.4 1.6 19 5.4 0.1 2.7 2 0 0 2 2 2 0 BDHCT (NUC031) domain UVR PF02151.19 CRK13159.1 - 0.22 11.3 3.0 0.67 9.8 0.1 3.0 3 0 0 3 3 3 0 UvrB/uvrC motif PI3_PI4_kinase PF00454.27 CRK13161.1 - 7.1e-52 176.7 0.0 1.5e-51 175.7 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 CRK13161.1 - 1.5e-32 113.2 6.9 2.8e-32 112.3 6.9 1.5 1 0 0 1 1 1 1 FAT domain UME PF08064.13 CRK13161.1 - 3.6e-29 100.7 0.1 2.8e-28 97.8 0.1 2.8 1 0 0 1 1 1 1 UME (NUC010) domain zf-PARP PF00645.18 CRK13161.1 - 8.5e-20 71.4 0.4 2.5e-19 69.9 0.4 1.9 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region TetR_C_24 PF17932.1 CRK13161.1 - 0.00013 22.2 0.3 0.84 9.9 0.0 2.9 2 0 0 2 2 2 2 Tetracyclin repressor-like, C-terminal domain Dynein_attach_N PF15867.5 CRK13161.1 - 0.0038 17.2 0.7 5 7.2 0.1 2.8 2 0 0 2 2 2 2 Dynein attachment factor N-terminus SH PF01445.17 CRK13161.1 - 0.16 12.0 1.5 24 5.0 0.1 2.7 2 0 0 2 2 2 0 Viral small hydrophobic protein MFS_1 PF07690.16 CRK13162.1 - 2.2e-38 132.1 50.6 3.1e-37 128.3 45.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 CRK13162.1 - 0.00014 20.9 25.9 0.004 16.1 12.4 2.6 2 1 1 3 3 3 2 MFS_1 like family PRO8NT PF08082.11 CRK13162.1 - 0.22 11.5 0.5 0.38 10.7 0.5 1.3 1 0 0 1 1 1 0 PRO8NT (NUC069), PrP8 N-terminal domain OATP PF03137.20 CRK13162.1 - 0.54 8.5 18.8 0.022 13.1 11.6 2.3 1 1 2 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Peptidase_S26 PF10502.9 CRK13163.1 - 0.033 14.0 0.0 6.7 6.5 0.0 2.4 2 0 0 2 2 2 0 Signal peptidase, peptidase S26 ATP-synt_C PF00137.21 CRK13164.1 - 8e-19 67.7 10.4 1.4e-18 67.0 10.4 1.4 1 0 0 1 1 1 1 ATP synthase subunit C Autoind_bind PF03472.15 CRK13164.1 - 0.052 13.0 0.1 0.14 11.6 0.1 1.7 1 1 0 1 1 1 0 Autoinducer binding domain MFS_1 PF07690.16 CRK13165.1 - 3.2e-34 118.4 42.7 6.2e-34 117.5 42.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 CRK13165.1 - 0.0079 15.1 28.6 0.0063 15.4 10.0 2.1 2 0 0 2 2 2 2 MFS_1 like family OATP PF03137.20 CRK13165.1 - 0.025 12.9 15.3 0.0086 14.4 12.3 1.7 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF2107 PF09880.9 CRK13165.1 - 2.7 8.2 8.3 0.2 11.8 2.5 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2107) ATP-synt_C PF00137.21 CRK13167.1 - 5.2e-20 71.6 10.4 6.5e-20 71.2 10.4 1.1 1 0 0 1 1 1 1 ATP synthase subunit C CNH PF00780.22 CRK13170.1 - 1.5e-130 434.7 0.1 2.6e-76 256.8 0.0 3.1 4 0 0 4 4 4 2 CNH domain PH_5 PF15405.6 CRK13170.1 - 2.5e-88 293.1 0.0 1.2e-42 145.2 0.0 2.6 2 0 0 2 2 2 2 Pleckstrin homology domain RhoGEF PF00621.20 CRK13170.1 - 1.7e-74 250.0 1.8 5e-36 124.6 0.1 2.4 2 0 0 2 2 2 2 RhoGEF domain DEP PF00610.21 CRK13170.1 - 8e-26 89.9 0.3 6.9e-13 48.5 0.0 2.7 2 0 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_13 PF16652.5 CRK13170.1 - 0.00092 19.1 2.9 1.6 8.5 0.0 3.9 6 0 0 6 6 6 2 Pleckstrin homology domain SKG6 PF08693.10 CRK13170.1 - 0.0012 18.2 0.5 0.0024 17.2 0.5 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF818 PF05677.12 CRK13170.1 - 0.056 12.4 0.3 9.4 5.1 0.0 2.2 2 0 0 2 2 2 0 Chlamydia CHLPS protein (DUF818) KN_motif PF12075.8 CRK13170.1 - 0.069 13.0 1.4 16 5.4 0.1 2.8 2 0 0 2 2 2 0 KN motif DUF643 PF04867.12 CRK13170.1 - 0.18 12.4 2.4 18 6.0 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF643) DUF2256 PF10013.9 CRK13170.1 - 0.24 11.5 1.0 35 4.6 0.1 2.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) DUF4336 PF14234.6 CRK13171.1 - 1.8e-14 53.7 0.0 3.2e-08 33.1 0.0 2.6 1 1 1 2 2 2 2 Domain of unknown function (DUF4336) MTBP_N PF14918.6 CRK13171.1 - 0.15 11.6 1.4 0.22 11.0 1.4 1.2 1 0 0 1 1 1 0 MDM2-binding Macoilin PF09726.9 CRK13171.1 - 0.75 8.3 3.3 0.95 7.9 3.3 1.1 1 0 0 1 1 1 0 Macoilin family Nse4_C PF08743.10 CRK13172.1 - 2.3e-19 69.5 0.0 1.4e-18 66.9 0.0 2.5 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 CRK13172.1 - 1.4e-15 57.1 0.0 1.4e-15 57.1 0.0 2.5 3 0 0 3 3 3 1 Binding domain of Nse4/EID3 to Nse3-MAGE Nse4_C PF08743.10 CRK13173.1 - 3e-18 65.9 0.2 1.1e-17 64.1 0.0 2.0 2 0 0 2 2 2 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 CRK13173.1 - 3e-16 59.2 0.0 3e-16 59.2 0.0 3.2 3 0 0 3 3 3 1 Binding domain of Nse4/EID3 to Nse3-MAGE IDO PF01231.18 CRK13173.1 - 0.09 11.5 0.8 0.45 9.2 0.3 1.9 2 0 0 2 2 2 0 Indoleamine 2,3-dioxygenase TetR PF13972.6 CRK13173.1 - 1.1 8.9 4.5 0.86 9.3 0.3 2.3 2 0 0 2 2 2 0 Bacterial transcriptional repressor Iwr1 PF08574.10 CRK13173.1 - 1.6 9.8 8.5 20 6.3 5.4 2.8 2 0 0 2 2 2 0 Transcription factor Iwr1 Muted PF14942.6 CRK13173.1 - 2.7 8.3 8.7 10 6.5 3.1 2.3 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein PI3Ka PF00613.20 CRK13174.1 - 1.3e-56 190.9 0.8 2.1e-56 190.3 0.8 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 CRK13174.1 - 2.2e-46 158.7 0.3 1.6e-43 149.3 0.1 2.5 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 CRK13174.1 - 1e-31 109.8 0.0 1.6e-31 109.1 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 ADH_zinc_N PF00107.26 CRK13175.1 - 1.5e-14 54.1 0.2 1e-13 51.4 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase HTH_23 PF13384.6 CRK13175.1 - 6.2e-07 29.0 0.0 0.062 13.1 0.0 2.7 3 0 0 3 3 3 2 Homeodomain-like domain ADH_N_2 PF16884.5 CRK13175.1 - 0.026 14.4 0.0 9 6.2 0.0 2.8 2 1 0 2 2 2 0 N-terminal domain of oxidoreductase ADH_N PF08240.12 CRK13175.1 - 0.028 14.3 0.0 1 9.2 0.0 2.4 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-like domain DUF1858 PF08984.11 CRK13175.1 - 0.06 13.5 0.2 18 5.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1858) PNP_UDP_1 PF01048.20 CRK13175.1 - 0.096 11.9 0.0 10 5.3 0.0 2.8 2 2 0 2 2 2 0 Phosphorylase superfamily UQ_con PF00179.26 CRK13177.1 - 1e-47 161.3 0.0 1.1e-47 161.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CRK13177.1 - 0.00052 19.7 0.0 0.00071 19.3 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 CRK13177.1 - 0.0043 16.9 0.1 0.008 16.0 0.1 1.5 1 1 0 1 1 1 1 UEV domain RWD PF05773.22 CRK13177.1 - 0.074 13.3 0.0 0.093 13.0 0.0 1.3 1 0 0 1 1 1 0 RWD domain WD40 PF00400.32 CRK13178.1 - 6.2e-10 39.5 16.8 0.001 19.9 0.3 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat RWD PF05773.22 CRK13178.1 - 0.0089 16.3 0.0 0.019 15.3 0.0 1.5 1 0 0 1 1 1 1 RWD domain Glyco_transf_64 PF09258.10 CRK13178.1 - 0.17 11.2 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 64 domain Clr5 PF14420.6 CRK13179.1 - 4.7e-20 71.6 1.5 2.7e-19 69.1 0.8 2.6 2 0 0 2 2 2 1 Clr5 domain DUF1917 PF08939.10 CRK13179.1 - 0.87 9.4 7.0 0.041 13.8 1.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1917) DUF3490 PF11995.8 CRK13179.1 - 1.3 8.9 5.4 0.14 12.0 0.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3490) STAG PF08514.11 CRK13179.1 - 3.1 7.7 8.2 0.68 9.9 0.4 2.6 2 0 0 2 2 2 0 STAG domain Hydin_ADK PF17213.3 CRK13179.1 - 4.4 7.5 14.3 1.2e+03 -0.4 14.3 2.8 1 1 0 1 1 1 0 Hydin Adenylate kinase-like domain ECH_1 PF00378.20 CRK13180.1 - 3.3e-37 128.2 0.0 4e-37 127.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CRK13180.1 - 8.5e-23 81.4 0.1 2.7e-22 79.7 0.1 1.7 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase LNS2 PF08235.13 CRK13181.1 - 1.7e-93 312.3 0.0 2.3e-93 311.9 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 CRK13181.1 - 4.5e-43 145.4 0.0 2e-42 143.3 0.0 2.1 2 0 0 2 2 2 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.14 CRK13181.1 - 0.0044 16.6 0.0 0.18 11.4 0.0 2.5 2 0 0 2 2 2 1 HAD superfamily, subfamily IIIB (Acid phosphatase) PI3K_1B_p101 PF10486.9 CRK13181.1 - 0.36 8.5 14.6 0.55 8.0 14.6 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit TFIID-31kDa PF02291.15 CRK13182.1 - 1.2e-42 144.8 0.0 2e-42 144.1 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit TFIIA PF03153.13 CRK13182.1 - 0.025 14.6 9.9 0.033 14.2 9.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CRK13182.1 - 0.26 10.8 14.2 0.34 10.5 14.2 1.2 1 0 0 1 1 1 0 Spt20 family DUF601 PF04642.12 CRK13182.1 - 0.31 10.5 3.9 0.41 10.1 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF601 Presenilin PF01080.17 CRK13182.1 - 0.75 8.5 5.7 0.88 8.3 5.7 1.1 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 CRK13182.1 - 1 8.0 5.9 1 7.9 5.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF3464 PF11947.8 CRK13182.1 - 1.4 8.7 4.7 2.5 7.8 4.7 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Roughex PF06020.11 CRK13182.1 - 1.9 7.5 7.6 3.7 6.5 7.6 1.4 1 0 0 1 1 1 0 Drosophila roughex protein DUF4551 PF15087.6 CRK13182.1 - 6.4 5.5 8.2 7.6 5.2 8.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) SOG2 PF10428.9 CRK13182.1 - 8.9 5.4 14.3 10 5.2 14.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Pex14_N PF04695.13 CRK13182.1 - 9.6 6.8 19.8 15 6.2 19.8 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Histidinol_dh PF00815.20 CRK13183.1 - 2.4e-268 889.7 14.4 1e-146 489.1 2.0 3.2 1 1 2 3 3 3 3 Histidinol dehydrogenase PRA-CH PF01502.18 CRK13183.1 - 1.1e-24 86.0 0.1 2.4e-24 84.9 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 CRK13183.1 - 2.7e-13 50.2 0.5 6.6e-13 48.9 0.5 1.7 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase Orexin_rec2 PF03827.13 CRK13183.1 - 0.0047 16.9 0.0 15 5.6 0.0 3.5 3 0 0 3 3 3 1 Orexin receptor type 2 TFIIS_C PF01096.18 CRK13183.1 - 0.05 13.5 0.3 66 3.5 0.0 3.3 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) MCR_alpha_N PF02745.15 CRK13183.1 - 0.1 12.0 0.0 79 2.4 0.0 3.2 3 0 0 3 3 3 0 Methyl-coenzyme M reductase alpha subunit, N-terminal domain Phage_GPL PF05926.11 CRK13183.1 - 0.47 10.5 6.0 45 4.0 0.1 3.5 3 0 0 3 3 3 0 Phage head completion protein (GPL) DUF3168 PF11367.8 CRK13183.1 - 0.54 10.5 7.6 37 4.5 0.2 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3168) Usp PF00582.26 CRK13183.1 - 2.9 8.4 9.2 76 3.8 0.1 4.1 4 0 0 4 4 4 0 Universal stress protein family Peptidase_M16 PF00675.20 CRK13184.1 - 1.2e-57 194.1 0.3 5.8e-56 188.6 0.2 2.3 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CRK13184.1 - 6.3e-35 120.8 0.1 2.9e-34 118.7 0.0 1.9 2 0 0 2 2 2 1 Peptidase M16 inactive domain M16C_assoc PF08367.11 CRK13184.1 - 0.099 11.8 0.2 0.2 10.8 0.2 1.5 1 1 0 1 1 1 0 Peptidase M16C associated RbsD_FucU PF05025.13 CRK13184.1 - 0.14 12.6 0.1 0.43 11.0 0.0 1.9 2 0 0 2 2 2 0 RbsD / FucU transport protein family Raffinose_syn PF05691.12 CRK13185.1 - 1.4e-48 165.3 0.8 6.6e-46 156.5 0.8 2.2 1 1 0 1 1 1 1 Raffinose synthase or seed imbibition protein Sip1 Melibiase PF02065.18 CRK13185.1 - 0.0036 16.3 0.4 0.0053 15.8 0.4 1.2 1 0 0 1 1 1 1 Melibiase UDPGP PF01704.18 CRK13186.1 - 3.2e-53 180.8 0.0 4.4e-53 180.4 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 CRK13186.1 - 0.029 14.7 0.0 0.082 13.3 0.0 1.7 1 0 0 1 1 1 0 MobA-like NTP transferase domain CwsA PF10814.8 CRK13187.1 - 0.03 14.5 2.9 1.4 9.1 0.1 3.0 2 0 0 2 2 2 0 Cell wall synthesis protein CwsA Peptidase_M16 PF00675.20 CRK13188.1 - 9.5e-14 51.6 0.0 1.8e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CRK13188.1 - 6.3e-13 49.1 0.0 9.6e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase M16 inactive domain Raffinose_syn PF05691.12 CRK13189.1 - 2.4e-50 171.1 1.1 9.1e-42 142.8 0.1 3.1 2 1 1 3 3 3 3 Raffinose synthase or seed imbibition protein Sip1 Melibiase PF02065.18 CRK13189.1 - 0.0024 16.9 0.8 0.0038 16.2 0.8 1.2 1 0 0 1 1 1 1 Melibiase UDPGP PF01704.18 CRK13191.1 - 2.2e-45 155.1 0.0 3.2e-45 154.5 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 CRK13191.1 - 0.035 14.5 0.0 0.1 13.0 0.0 1.8 1 0 0 1 1 1 0 MobA-like NTP transferase domain Syja_N PF02383.18 CRK13193.1 - 3.4e-87 292.8 0.0 4.3e-87 292.4 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain Ras PF00071.22 CRK13194.1 - 5.4e-59 198.4 0.3 6.3e-59 198.2 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CRK13194.1 - 3.2e-36 124.2 0.2 5.8e-36 123.3 0.1 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CRK13194.1 - 2.1e-15 56.6 0.1 2.6e-15 56.3 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CRK13194.1 - 4e-07 29.6 0.0 4.8e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CRK13194.1 - 9.2e-07 28.6 0.0 1.2e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CRK13194.1 - 2.4e-06 27.6 0.0 3.7e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CRK13194.1 - 3.5e-05 23.8 1.4 0.074 12.9 0.2 2.4 1 1 2 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 CRK13194.1 - 0.024 15.0 0.2 0.044 14.2 0.2 1.5 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 CRK13194.1 - 0.087 12.2 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein AAA_22 PF13401.6 CRK13194.1 - 0.11 12.8 0.0 4 7.7 0.0 2.3 1 1 1 2 2 2 0 AAA domain G-alpha PF00503.20 CRK13194.1 - 0.14 11.3 0.3 2.9 7.0 0.1 2.3 1 1 1 2 2 2 0 G-protein alpha subunit Mitofilin PF09731.9 CRK13195.1 - 9.7e-149 497.1 17.9 2.9e-126 422.9 17.1 2.1 1 1 1 2 2 2 2 Mitochondrial inner membrane protein DUF2959 PF11172.8 CRK13195.1 - 0.00021 21.5 3.1 0.00051 20.2 3.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2959) DUF4363 PF14276.6 CRK13195.1 - 0.17 12.0 0.5 1.8 8.7 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4363) Mur_ligase_M PF08245.12 CRK13196.1 - 5.4e-07 29.8 0.3 3e-05 24.1 0.3 2.9 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 CRK13196.1 - 0.038 14.3 0.0 0.081 13.2 0.0 1.6 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain Mur_ligase_M PF08245.12 CRK13197.1 - 0.0031 17.6 0.0 0.0084 16.1 0.0 1.7 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 CRK13197.1 - 0.011 16.0 0.0 0.023 14.9 0.0 1.6 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain RTA1 PF04479.13 CRK13200.1 - 2.4e-39 135.1 6.2 2.4e-39 135.1 6.2 1.4 2 0 0 2 2 2 1 RTA1 like protein DUF1461 PF07314.11 CRK13200.1 - 0.17 11.8 1.5 0.35 10.7 1.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) DUF4574 PF15141.6 CRK13200.1 - 3.8 7.5 5.5 8.8 6.3 5.5 1.5 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 SpvB PF03534.13 CRK13201.1 - 1.3e-65 221.5 0.2 3.3e-65 220.1 0.1 1.7 2 0 0 2 2 2 1 Salmonella virulence plasmid 65kDa B protein TcdB_toxin_midN PF12256.8 CRK13201.1 - 3.1e-31 108.1 0.6 3.2e-23 82.0 0.0 6.8 5 1 1 6 6 6 3 Insecticide toxin TcdB middle/N-terminal region TcdB_toxin_midC PF12255.8 CRK13201.1 - 4e-29 101.6 0.0 9.2e-29 100.4 0.0 1.6 1 0 0 1 1 1 1 Insecticide toxin TcdB middle/C-terminal region VCBS PF13517.6 CRK13201.1 - 8e-12 45.6 6.0 0.0034 18.0 1.7 5.2 4 0 0 4 4 4 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella RHS_repeat PF05593.14 CRK13201.1 - 3.5e-10 40.2 27.6 0.43 11.2 0.4 11.8 11 2 2 13 13 13 4 RHS Repeat Ank_3 PF13606.6 CRK13202.1 - 0.00021 21.5 0.1 0.026 15.0 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 CRK13202.1 - 0.0071 16.9 0.0 0.2 12.3 0.0 2.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 CRK13202.1 - 0.013 15.9 0.2 0.1 13.1 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeat Ank_2 PF12796.7 CRK13202.1 - 0.028 15.0 0.0 0.33 11.6 0.0 1.8 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Mur_ligase_M PF08245.12 CRK13203.1 - 0.00014 21.9 0.0 0.00046 20.2 0.0 1.8 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 CRK13203.1 - 0.032 14.5 0.0 0.073 13.3 0.0 1.6 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain Aldedh PF00171.22 CRK13204.1 - 5.9e-148 493.2 0.1 7.2e-148 492.9 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 CRK13204.1 - 0.00018 21.0 0.1 0.45 9.9 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) LuxC PF05893.14 CRK13204.1 - 0.0003 20.0 0.0 0.00045 19.4 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) MFS_1 PF07690.16 CRK13205.1 - 6.6e-28 97.6 23.9 9.9e-28 97.1 23.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily RTA1 PF04479.13 CRK13206.1 - 1.2e-46 158.9 9.5 1.6e-46 158.5 9.5 1.1 1 0 0 1 1 1 1 RTA1 like protein SpvB PF03534.13 CRK13207.1 - 3.1e-143 476.3 0.8 1.5e-107 359.1 0.1 2.5 2 0 0 2 2 2 2 Salmonella virulence plasmid 65kDa B protein TcdB_toxin_midN PF12256.8 CRK13207.1 - 1.8e-31 108.9 2.4 8.7e-24 83.8 0.0 7.1 6 1 1 7 7 7 2 Insecticide toxin TcdB middle/N-terminal region TcdB_toxin_midC PF12255.8 CRK13207.1 - 8.4e-29 100.6 0.0 8.4e-29 100.6 0.0 1.9 2 0 0 2 2 2 1 Insecticide toxin TcdB middle/C-terminal region RHS_repeat PF05593.14 CRK13207.1 - 3.8e-13 49.6 20.0 0.0055 17.2 0.6 11.2 11 1 1 12 12 12 5 RHS Repeat VCBS PF13517.6 CRK13207.1 - 3.1e-11 43.7 6.7 0.0063 17.1 2.1 5.1 4 0 0 4 4 4 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella AHH PF14412.6 CRK13207.1 - 0.017 15.1 0.0 0.046 13.8 0.0 1.6 1 0 0 1 1 1 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH TcA_TcB_BD PF18276.1 CRK13208.1 - 1.9e-109 365.2 0.0 3.1e-109 364.5 0.0 1.4 1 0 0 1 1 1 1 Tc toxin complex TcA C-terminal TcB-binding domain Neuraminidase PF18413.1 CRK13208.1 - 3e-66 222.3 1.9 5.5e-33 114.0 0.1 2.4 2 0 0 2 2 2 2 Neuraminidase-like domain VRP1 PF03538.14 CRK13208.1 - 3.3e-07 30.0 0.0 0.00019 21.0 0.0 2.5 1 1 1 2 2 2 2 Salmonella virulence plasmid 28.1kDa A protein Bac_GH3_C PF18034.1 CRK13208.1 - 0.0023 17.7 0.2 3.4 7.4 0.0 2.5 2 0 0 2 2 2 2 Bacterial Glycosyl hydrolase family 3 C-terminal domain HBD PF18534.1 CRK13208.1 - 0.006 16.7 0.1 7.8 6.7 0.0 3.1 2 0 0 2 2 2 2 Helical bundle domain PA14 PF07691.12 CRK13208.1 - 0.04 13.7 0.0 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 PA14 domain ACT_7 PF13840.6 CRK13208.1 - 0.058 13.2 0.3 0.17 11.7 0.3 1.7 1 0 0 1 1 1 0 ACT domain BING4CT PF08149.11 CRK13208.1 - 0.12 12.2 0.0 28 4.6 0.0 2.6 2 0 0 2 2 2 0 BING4CT (NUC141) domain PH_11 PF15413.6 CRK13208.1 - 0.19 12.1 0.1 31 5.1 0.0 2.8 2 0 0 2 2 2 0 Pleckstrin homology domain VRP1 PF03538.14 CRK13210.1 - 3.3e-08 33.3 0.0 7.8e-05 22.2 0.0 2.5 2 1 1 3 3 3 2 Salmonella virulence plasmid 28.1kDa A protein PA14 PF07691.12 CRK13210.1 - 0.023 14.5 0.0 0.1 12.4 0.0 1.9 2 0 0 2 2 2 0 PA14 domain zf-C2H2 PF00096.26 CRK13211.1 - 1.2e-05 25.5 13.0 0.00047 20.5 0.7 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type Sina PF03145.16 CRK13211.1 - 0.016 15.2 7.4 0.44 10.5 2.6 2.1 1 1 1 2 2 2 0 Seven in absentia protein family zf-Di19 PF05605.12 CRK13211.1 - 0.024 14.9 4.8 0.17 12.2 3.7 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_8 PF15909.5 CRK13211.1 - 0.028 14.7 1.9 0.05 13.9 1.9 1.4 1 0 0 1 1 1 0 C2H2-type zinc ribbon zf-C2H2_4 PF13894.6 CRK13211.1 - 0.039 14.8 13.8 0.38 11.7 0.8 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger GAGA PF09237.11 CRK13211.1 - 0.046 13.5 0.8 0.046 13.5 0.8 2.2 2 0 0 2 2 2 0 GAGA factor zf-C2H2_aberr PF17017.5 CRK13211.1 - 0.22 11.7 2.4 2.9 8.0 0.1 2.3 1 1 1 2 2 2 0 Aberrant zinc-finger DUF1644 PF07800.12 CRK13211.1 - 1.9 8.5 8.5 7.9 6.5 8.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1644) zf-C2H2_jaz PF12171.8 CRK13211.1 - 2.1 8.7 5.5 0.75 10.2 1.3 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding NACHT PF05729.12 CRK13213.1 - 2.6e-08 34.0 0.7 6.4e-08 32.7 0.3 1.8 2 0 0 2 2 2 1 NACHT domain Ank PF00023.30 CRK13213.1 - 1.5e-07 31.5 0.0 0.039 14.4 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat AAA_16 PF13191.6 CRK13213.1 - 2.4e-07 31.3 0.5 7.9e-07 29.6 0.5 1.9 1 0 0 1 1 1 1 AAA ATPase domain Ank_2 PF12796.7 CRK13213.1 - 4.4e-05 24.0 0.0 0.0012 19.4 0.0 2.9 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CRK13213.1 - 0.00011 22.6 0.1 0.0021 18.6 0.0 3.0 3 0 0 3 3 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 CRK13213.1 - 0.00095 19.5 0.0 0.37 11.5 0.0 3.1 2 0 0 2 2 2 1 Ankyrin repeat AAA_22 PF13401.6 CRK13213.1 - 0.001 19.3 0.1 0.0036 17.6 0.1 2.0 2 0 0 2 2 2 1 AAA domain Ank_5 PF13857.6 CRK13213.1 - 0.002 18.4 0.0 2.6 8.5 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) NB-ARC PF00931.22 CRK13213.1 - 0.011 14.9 0.2 0.027 13.7 0.2 1.6 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 CRK13213.1 - 0.11 13.0 0.0 0.23 11.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 CRK13213.1 - 0.16 12.1 0.2 0.88 9.7 0.2 2.3 2 1 0 2 2 2 0 AAA domain Pkinase PF00069.25 CRK13215.1 - 1e-72 244.7 0.0 1.5e-72 244.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK13215.1 - 2.1e-36 125.6 0.0 6.7e-36 123.9 0.0 1.9 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CRK13215.1 - 0.00027 20.4 0.4 0.47 9.7 0.0 2.6 3 0 0 3 3 3 2 Kinase-like Pkinase_fungal PF17667.1 CRK13215.1 - 0.014 14.2 0.3 0.043 12.6 0.0 1.9 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 CRK13215.1 - 0.036 14.0 0.5 0.16 11.9 0.0 2.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family Mucin PF01456.17 CRK13216.1 - 0.049 13.6 1.3 0.066 13.2 1.3 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Peptidase_S8 PF00082.22 CRK13218.1 - 1.3e-47 162.5 37.0 2.2e-28 99.4 13.7 2.3 2 0 0 2 2 2 2 Subtilase family Inhibitor_I9 PF05922.16 CRK13218.1 - 2.6e-31 108.1 0.1 4e-16 59.5 0.0 2.6 2 0 0 2 2 2 2 Peptidase inhibitor I9 Orn_Arg_deC_N PF02784.16 CRK13218.1 - 0.00042 19.8 1.0 0.29 10.5 0.0 2.2 2 0 0 2 2 2 2 Pyridoxal-dependent decarboxylase, pyridoxal binding domain LexA_DNA_bind PF01726.16 CRK13218.1 - 0.0019 17.9 0.2 3.3 7.6 0.0 2.5 2 0 0 2 2 2 2 LexA DNA binding domain Transposase_24 PF03004.14 CRK13218.1 - 0.002 18.2 0.0 2.8 8.0 0.0 2.4 2 0 0 2 2 2 2 Plant transposase (Ptta/En/Spm family) F420H2_quin_red PF04075.14 CRK13218.1 - 0.1 12.7 0.5 23 5.1 0.1 2.6 2 0 0 2 2 2 0 F420H(2)-dependent quinone reductase Prim_Zn_Ribbon PF08273.12 CRK13218.1 - 0.12 12.7 2.2 15 6.0 0.2 2.4 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase RHS_repeat PF05593.14 CRK13218.1 - 1.5 9.4 11.3 6.6 7.4 1.0 3.2 3 0 0 3 3 3 0 RHS Repeat Pkinase PF00069.25 CRK13221.1 - 7e-32 110.8 0.0 1e-31 110.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK13221.1 - 3.7e-15 55.9 0.0 6.7e-15 55.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CRK13221.1 - 2.8e-05 23.6 0.0 4.8e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CRK13221.1 - 0.0019 18.1 0.1 0.0019 18.1 0.1 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 CRK13221.1 - 0.12 11.7 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Tyrosinase PF00264.20 CRK13223.1 - 8.5e-31 108.0 0.3 4.3e-30 105.6 0.0 1.9 2 0 0 2 2 2 1 Common central domain of tyrosinase PAP2_3 PF14378.6 CRK13224.1 - 6.4e-35 120.6 10.1 6.4e-35 120.6 10.1 1.7 2 0 0 2 2 2 1 PAP2 superfamily Glyco_hydro_28 PF00295.17 CRK13224.1 - 7.9e-29 100.7 0.3 1.3e-28 100.1 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 DUF4470 PF14737.6 CRK13224.1 - 2.7e-08 33.9 0.0 7.2e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) TPR_MalT PF17874.1 CRK13224.1 - 0.0035 16.8 0.1 0.0071 15.8 0.1 1.4 1 0 0 1 1 1 1 MalT-like TPR region TPR_12 PF13424.6 CRK13224.1 - 0.004 17.4 0.9 0.011 16.0 0.9 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat Beta_helix PF13229.6 CRK13224.1 - 0.0071 16.2 1.3 0.012 15.4 1.3 1.3 1 0 0 1 1 1 1 Right handed beta helix region TPR_14 PF13428.6 CRK13224.1 - 0.012 16.3 0.8 0.05 14.4 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat PAP2 PF01569.21 CRK13224.1 - 0.048 13.4 2.4 0.12 12.2 2.4 1.6 1 0 0 1 1 1 0 PAP2 superfamily TPR_8 PF13181.6 CRK13224.1 - 0.075 13.3 1.0 0.18 12.1 1.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 CRK13224.1 - 0.21 11.8 1.0 0.54 10.5 1.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Abhydrolase_6 PF12697.7 CRK13225.1 - 1.3e-16 61.9 3.2 1.7e-16 61.5 3.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CRK13225.1 - 1.2e-13 51.3 0.0 5.5e-12 45.9 0.0 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CRK13225.1 - 6.4e-13 48.5 0.1 2.8e-12 46.4 0.1 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Alpha-amylase PF00128.24 CRK13226.1 - 9.7e-47 160.2 2.8 5.6e-31 108.3 1.3 3.1 1 1 1 2 2 2 2 Alpha amylase, catalytic domain DUF1966 PF09260.11 CRK13226.1 - 0.00027 21.1 0.0 0.00082 19.6 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1966) hDGE_amylase PF14701.6 CRK13226.1 - 0.041 13.0 0.0 0.066 12.3 0.0 1.2 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Aminotran_5 PF00266.19 CRK13226.1 - 0.06 12.3 0.1 0.12 11.3 0.1 1.4 1 0 0 1 1 1 0 Aminotransferase class-V XOO_2897-deam PF14440.6 CRK13228.1 - 0.016 15.3 4.6 4.5 7.4 0.0 4.8 3 2 2 5 5 5 0 Xanthomonas XOO_2897-like deaminase Pet191_N PF10203.9 CRK13228.1 - 7.8 6.9 17.4 5.7 7.3 0.1 4.4 5 1 0 5 5 5 0 Cytochrome c oxidase assembly protein PET191 GMC_oxred_N PF00732.19 CRK13230.1 - 9.8e-52 176.1 0.0 6.6e-36 124.2 0.0 2.3 1 1 1 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 CRK13230.1 - 1.4e-32 113.2 0.0 2.5e-32 112.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 CRK13230.1 - 1.9e-05 24.8 0.1 6.4e-05 23.1 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 CRK13230.1 - 0.00079 18.8 0.3 0.2 10.9 0.2 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CRK13230.1 - 0.001 18.2 0.5 0.0019 17.4 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 CRK13230.1 - 0.0027 16.8 0.1 0.0043 16.2 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Epimerase PF01370.21 CRK13230.1 - 0.0044 16.5 0.0 0.01 15.3 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DAO PF01266.24 CRK13230.1 - 0.0059 16.2 0.7 0.017 14.7 0.3 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase DUF3731 PF12531.8 CRK13230.1 - 0.032 14.1 0.1 0.053 13.3 0.1 1.2 1 0 0 1 1 1 0 DNA-K related protein HI0933_like PF03486.14 CRK13230.1 - 0.1 11.3 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein TrkA_N PF02254.18 CRK13230.1 - 0.16 12.2 0.0 0.39 11.0 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Ank_4 PF13637.6 CRK13231.1 - 1.2e-13 51.2 0.1 2.8e-08 34.1 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 CRK13231.1 - 4.9e-11 42.6 1.5 1.9e-10 40.8 0.2 2.5 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CRK13231.1 - 6.8e-10 39.4 0.0 1.7e-09 38.2 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 CRK13231.1 - 2.7e-09 37.1 0.2 0.0013 19.1 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 CRK13231.1 - 1.8e-07 30.9 0.1 0.02 15.4 0.0 4.2 4 0 0 4 4 4 1 Ankyrin repeat Helo_like_N PF17111.5 CRK13231.1 - 4.5e-05 22.9 2.2 0.00011 21.7 2.1 1.5 1 1 1 2 2 2 1 Fungal N-terminal domain of STAND proteins DUF3530 PF12048.8 CRK13231.1 - 0.036 13.5 0.0 0.064 12.7 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3530) SesA PF17107.5 CRK13231.1 - 0.06 13.5 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Toprim_3 PF13362.6 CRK13231.1 - 0.11 12.9 0.2 6 7.3 0.0 2.6 2 0 0 2 2 2 0 Toprim domain MFS_1 PF07690.16 CRK13233.1 - 4.3e-31 108.1 34.3 4.3e-31 108.1 34.3 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily DSRB PF10781.9 CRK13233.1 - 0.033 13.8 0.0 0.076 12.7 0.0 1.6 1 0 0 1 1 1 0 Dextransucrase DSRB Aminotran_4 PF01063.19 CRK13234.1 - 2.3e-30 106.1 0.0 3e-30 105.8 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Fungal_trans PF04082.18 CRK13235.1 - 1.3e-21 76.8 0.2 2e-21 76.2 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK13235.1 - 4.7e-09 36.2 11.2 1.1e-08 35.0 11.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 CRK13236.1 - 3.8e-09 35.9 0.3 4.3e-09 35.8 0.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK13236.1 - 1.6e-07 30.6 10.2 2e-07 30.3 10.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4386 PF14329.6 CRK13236.1 - 0.0012 18.7 4.1 0.0017 18.2 4.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4386) zf-CCHC PF00098.23 CRK13275.1 - 0.65 10.2 33.7 0.18 11.9 6.8 4.7 4 0 0 4 4 4 0 Zinc knuckle HET PF06985.11 CRK13276.1 - 1.9e-20 73.7 0.1 3e-20 73.1 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HATPase_c PF02518.26 CRK13278.1 - 1.4e-27 96.5 0.0 3.5e-26 91.9 0.0 2.8 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 CRK13278.1 - 4.3e-27 94.5 0.7 7.3e-27 93.8 0.7 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 CRK13278.1 - 4.7e-14 52.2 0.0 1.1e-13 51.0 0.0 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 CRK13278.1 - 0.0022 18.4 0.0 0.022 15.1 0.0 2.4 2 0 0 2 2 2 1 HAMP domain AA_permease_2 PF13520.6 CRK13279.1 - 2.2e-45 155.3 46.7 3e-44 151.5 46.7 1.9 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CRK13279.1 - 4.6e-11 42.0 41.0 4.1e-10 38.9 41.0 2.1 1 1 0 1 1 1 1 Amino acid permease DUF3493 PF11998.8 CRK13279.1 - 0.079 13.1 5.0 0.1 12.8 0.0 3.2 3 0 0 3 3 3 0 Low psii accumulation1 / Rep27 Cytochrome-c551 PF10643.9 CRK13279.1 - 0.21 11.2 6.3 0.28 10.7 1.3 2.5 2 0 0 2 2 2 0 Photosystem P840 reaction-centre cytochrome c-551 Cu_amine_oxid PF01179.20 CRK13280.1 - 2.4e-162 540.5 0.0 3.1e-162 540.2 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Amidohydro_3 PF07969.11 CRK13280.1 - 1.7e-53 182.8 0.2 2.4e-53 182.3 0.2 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 CRK13280.1 - 3.4e-08 33.2 0.0 4.5e-06 26.2 0.0 2.9 3 1 0 3 3 3 2 Amidohydrolase family Maf1 PF09174.10 CRK13281.1 - 1.1e-52 178.7 0.0 1.9e-52 178.0 0.0 1.4 1 0 0 1 1 1 1 Maf1 regulator Fungal_trans_2 PF11951.8 CRK13281.1 - 2.1e-16 59.7 0.0 5.1e-16 58.5 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Cu_amine_oxid PF01179.20 CRK13282.1 - 1.1e-162 541.7 0.0 1.3e-162 541.4 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 CRK13282.1 - 0.00011 22.4 0.1 0.00023 21.3 0.1 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Maf1 PF09174.10 CRK13283.1 - 3.4e-52 177.1 0.0 5.5e-52 176.4 0.0 1.4 1 0 0 1 1 1 1 Maf1 regulator Clat_adaptor_s PF01217.20 CRK13283.1 - 4e-50 169.4 1.3 6.5e-50 168.8 1.3 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Fungal_trans_2 PF11951.8 CRK13283.1 - 1.1e-15 57.4 0.0 9.3e-15 54.3 0.0 2.3 2 1 0 2 2 2 1 Fungal specific transcription factor domain Aldo_ket_red PF00248.21 CRK13285.1 - 3.8e-09 36.2 0.0 5.4e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 CRK13286.1 - 3e-06 26.6 0.0 3.7e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family ECR1_N PF14382.6 CRK13287.1 - 6.9e-18 64.2 1.2 6.9e-18 64.2 1.2 2.0 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 CRK13287.1 - 0.00024 21.4 0.0 0.00047 20.4 0.0 1.5 1 0 0 1 1 1 1 KH domain EXOSC1 PF10447.9 CRK13287.1 - 0.44 11.2 2.7 1.4 9.6 0.1 2.7 2 1 1 3 3 3 0 Exosome component EXOSC1/CSL4 Adap_comp_sub PF00928.21 CRK13289.1 - 1.9e-88 296.2 0.0 4.2e-43 147.6 0.0 2.1 1 1 1 2 2 2 2 Adaptor complexes medium subunit family Endonuc_Holl PF10107.9 CRK13289.1 - 4.7e-05 23.3 0.1 0.39 10.6 0.0 2.2 2 0 0 2 2 2 2 Endonuclease related to archaeal Holliday junction resolvase Clat_adaptor_s PF01217.20 CRK13289.1 - 0.00089 19.2 0.0 0.0013 18.7 0.0 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF2153 PF09921.9 CRK13289.1 - 0.14 11.9 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2153) Nucleoporin_C PF03177.14 CRK13290.1 - 4.8e-62 210.5 4.6 7e-62 210.0 4.6 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_C PF03177.14 CRK13291.1 - 3.8e-174 580.7 19.5 5.1e-174 580.3 19.5 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 CRK13291.1 - 1.6e-80 271.0 0.0 2e-80 270.7 0.0 1.1 1 0 0 1 1 1 1 Nup133 N terminal like Aconitase PF00330.20 CRK13292.1 - 1.7e-103 347.1 0.0 8.4e-103 344.8 0.0 1.9 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) AFG1_ATPase PF03969.16 CRK13292.1 - 3e-55 187.6 0.0 4.3e-27 95.0 0.0 5.1 5 0 0 5 5 5 5 AFG1-like ATPase Aconitase_C PF00694.19 CRK13292.1 - 1.6e-21 77.0 0.0 3.5e-21 75.9 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain AAA_16 PF13191.6 CRK13292.1 - 0.0074 16.7 0.2 1.4 9.3 0.0 2.7 1 1 0 2 2 2 1 AAA ATPase domain Bac_DnaA PF00308.18 CRK13292.1 - 0.012 15.4 0.0 4.4 7.1 0.0 2.8 2 1 0 2 2 2 0 Bacterial dnaA protein DUF2686 PF10887.8 CRK13292.1 - 0.13 11.2 0.1 0.25 10.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2686) Nucleoporin_N PF08801.11 CRK13293.1 - 1.3e-80 271.3 0.0 1.6e-80 271.0 0.0 1.1 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 CRK13293.1 - 2.5e-53 181.7 2.8 3.4e-53 181.3 2.8 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Aconitase PF00330.20 CRK13294.1 - 1.3e-104 350.8 0.0 1e-103 347.8 0.0 2.0 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 CRK13294.1 - 9.9e-22 77.7 0.0 2.1e-21 76.6 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF2686 PF10887.8 CRK13294.1 - 0.03 13.3 0.1 0.058 12.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2686) AFG1_ATPase PF03969.16 CRK13295.1 - 3.6e-56 190.6 0.0 1.4e-27 96.5 0.0 5.0 5 0 0 5 5 5 5 AFG1-like ATPase Bac_DnaA PF00308.18 CRK13295.1 - 0.0013 18.7 0.0 1.4 8.7 0.0 2.8 2 1 0 2 2 2 2 Bacterial dnaA protein AAA_16 PF13191.6 CRK13295.1 - 0.0013 19.2 0.3 0.44 10.9 0.0 2.8 2 1 1 3 3 3 2 AAA ATPase domain ABC_tran PF00005.27 CRK13295.1 - 0.12 12.9 0.0 6.8 7.2 0.0 2.4 2 0 0 2 2 2 0 ABC transporter AAA_29 PF13555.6 CRK13295.1 - 0.14 11.9 0.0 0.39 10.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 CRK13295.1 - 0.19 12.0 0.0 0.55 10.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain Sedlin_N PF04628.13 CRK13296.1 - 8.1e-13 48.6 0.0 1.1e-12 48.2 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 CRK13296.1 - 0.11 12.4 0.0 1.6 8.6 0.0 2.1 2 0 0 2 2 2 0 Sybindin-like family Pkinase PF00069.25 CRK13297.1 - 8.5e-26 90.9 0.0 6.5e-19 68.3 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CRK13297.1 - 4.2e-12 45.9 0.0 4.9e-11 42.4 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CRK13297.1 - 2e-07 30.2 0.1 2.7e-07 29.7 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Peptidase_M44 PF03410.13 CRK13297.1 - 0.023 13.3 0.1 0.33 9.5 0.0 2.0 1 1 1 2 2 2 0 Metallopeptidase from vaccinia pox APH PF01636.23 CRK13297.1 - 0.085 12.8 0.0 2.5 8.0 0.0 2.8 1 1 2 3 3 3 0 Phosphotransferase enzyme family EMP24_GP25L PF01105.24 CRK13298.1 - 7.2e-53 179.2 0.0 8.1e-53 179.1 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD USP7_ICP0_bdg PF12436.8 CRK13299.1 - 3.2e-94 314.8 12.3 1e-85 286.9 2.9 4.5 2 1 3 5 5 5 2 ICP0-binding domain of Ubiquitin-specific protease 7 UCH PF00443.29 CRK13299.1 - 3.7e-69 233.1 6.2 1.1e-45 156.2 0.8 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 CRK13299.1 - 3.3e-58 196.8 13.2 6.1e-57 192.7 1.2 5.2 4 2 1 6 6 6 1 Ubiquitin-specific protease C-terminal Tim17 PF02466.19 CRK13299.1 - 1.8e-37 128.1 8.5 3.3e-37 127.3 8.5 1.5 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family UCH_1 PF13423.6 CRK13299.1 - 7.4e-31 107.9 1.3 3.7e-17 62.9 0.0 3.1 2 2 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 CRK13299.1 - 2.5e-11 43.7 0.2 1.4e-08 34.8 0.0 3.6 3 1 0 3 3 3 1 MATH domain DUF3601 PF12208.8 CRK13299.1 - 0.005 16.9 0.8 5.5 7.2 0.1 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF3601) TnpB_IS66 PF05717.13 CRK13299.1 - 0.0053 16.7 0.0 7.7 6.5 0.0 3.0 3 0 0 3 3 3 2 IS66 Orf2 like protein Tautomerase_3 PF14832.6 CRK13299.1 - 0.011 15.9 0.3 9.8 6.4 0.0 2.8 3 0 0 3 3 3 0 Putative oxalocrotonate tautomerase enzyme Pkinase_C PF00433.24 CRK13299.1 - 0.4 11.4 1.7 47 4.8 0.1 2.9 2 0 0 2 2 2 0 Protein kinase C terminal domain SKIP_SNW PF02731.15 CRK13300.1 - 1.2e-72 242.8 9.3 7.5e-72 240.2 7.9 2.2 2 0 0 2 2 2 1 SKIP/SNW domain RmlD_sub_bind PF04321.17 CRK13301.1 - 1.2e-38 132.9 0.1 5.6e-35 120.8 0.0 2.0 2 0 0 2 2 2 2 RmlD substrate binding domain Epimerase PF01370.21 CRK13301.1 - 3.5e-10 39.7 0.0 1.2e-05 24.9 0.0 2.3 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 CRK13301.1 - 2.3e-09 36.8 0.0 8.2e-07 28.4 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 CRK13301.1 - 2.6e-05 23.4 0.0 0.0055 15.8 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 CRK13301.1 - 0.0037 16.7 0.1 0.11 11.9 0.0 2.5 3 0 0 3 3 3 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 CRK13301.1 - 0.02 14.5 0.2 0.14 11.7 0.1 2.0 2 0 0 2 2 2 0 NmrA-like family Polysacc_synt_2 PF02719.15 CRK13301.1 - 0.08 12.1 0.0 13 4.8 0.0 2.8 2 1 0 2 2 2 0 Polysaccharide biosynthesis protein Semialdhyde_dhC PF02774.18 CRK13301.1 - 0.12 12.5 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, dimerisation domain Tim17 PF02466.19 CRK13303.1 - 2.5e-39 134.1 8.2 3.5e-39 133.6 8.2 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family SKIP_SNW PF02731.15 CRK13304.1 - 1.4e-139 460.3 23.1 2.8e-71 238.4 7.9 4.3 5 0 0 5 5 5 2 SKIP/SNW domain Transformer PF06495.11 CRK13304.1 - 0.0038 17.4 43.9 0.045 13.8 17.5 2.9 2 0 0 2 2 2 2 Fruit fly transformer protein AF-4 PF05110.13 CRK13304.1 - 0.0046 15.1 32.0 0.016 13.4 9.8 2.2 2 0 0 2 2 2 2 AF-4 proto-oncoprotein Serglycin PF04360.12 CRK13304.1 - 0.017 15.1 1.7 5.4 7.0 0.2 2.5 2 0 0 2 2 2 0 Serglycin SR-25 PF10500.9 CRK13304.1 - 1.7 8.2 41.6 3.9 7.0 16.7 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein RmlD_sub_bind PF04321.17 CRK13305.1 - 6.2e-48 163.4 0.3 2.4e-44 151.6 0.2 2.5 2 0 0 2 2 2 2 RmlD substrate binding domain Epimerase PF01370.21 CRK13305.1 - 5.8e-21 75.1 0.0 1.2e-20 74.0 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CRK13305.1 - 1.6e-11 44.2 0.0 4.9e-11 42.6 0.0 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 CRK13305.1 - 6e-10 38.7 0.1 4.9e-08 32.5 0.0 2.5 1 1 1 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.19 CRK13305.1 - 3e-08 33.0 0.0 8.6e-08 31.5 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family PH PF00169.29 CRK13305.1 - 3.9e-06 27.3 0.9 0.15 12.6 0.1 2.6 2 0 0 2 2 2 2 PH domain Polysacc_synt_2 PF02719.15 CRK13305.1 - 4.4e-06 26.0 0.6 0.00024 20.3 0.6 2.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein UPF0058 PF01893.16 CRK13305.1 - 0.00036 20.8 0.8 1.5 9.1 0.1 2.7 2 0 0 2 2 2 2 Uncharacterised protein family UPF0058 MetOD2 PF18548.1 CRK13305.1 - 0.00069 19.7 0.0 2.4 8.3 0.0 2.6 2 0 0 2 2 2 2 Metanogen output domain 2 NAD_binding_3 PF03447.16 CRK13305.1 - 0.03 15.0 0.0 48 4.6 0.0 3.6 3 0 0 3 3 3 0 Homoserine dehydrogenase, NAD binding domain DUF4868 PF16162.5 CRK13305.1 - 0.28 11.1 2.2 18 5.2 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4868) Regulator_TrmB PF11495.8 CRK13306.1 - 0.1 11.8 0.5 0.18 11.0 0.5 1.4 1 1 0 1 1 1 0 Archaeal transcriptional regulator TrmB ANAPC8 PF04049.13 CRK13307.1 - 1.3e-17 64.1 0.2 1.7e-16 60.5 0.0 2.0 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 Dicty_REP PF05086.12 CRK13308.1 - 0.77 7.7 4.0 0.85 7.5 4.0 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein polyprenyl_synt PF00348.17 CRK13309.1 - 4.8e-90 301.1 0.0 7.1e-90 300.5 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase ANAPC8 PF04049.13 CRK13310.1 - 1.8e-57 193.3 0.0 1.4e-56 190.4 0.0 2.3 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_8 PF13181.6 CRK13310.1 - 1.4e-26 90.4 9.5 6.8e-05 22.8 0.0 8.4 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_1 PF00515.28 CRK13310.1 - 7.8e-24 82.5 4.3 0.00036 20.2 0.0 7.9 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 CRK13310.1 - 2.2e-15 55.4 20.0 0.076 13.2 0.0 9.2 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.6 CRK13310.1 - 4.5e-11 43.2 11.0 1.4e-05 25.6 0.1 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 CRK13310.1 - 9.8e-10 38.6 16.6 0.5 10.7 0.1 7.2 7 1 1 8 8 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 CRK13310.1 - 2.8e-09 37.0 22.4 0.0056 17.4 0.1 9.3 9 1 1 10 10 9 3 Tetratricopeptide repeat TPR_11 PF13414.6 CRK13310.1 - 1.8e-08 33.9 0.1 2.4e-06 27.1 0.1 3.8 5 0 0 5 5 5 1 TPR repeat TPR_9 PF13371.6 CRK13310.1 - 3.1e-06 27.2 10.5 1.3 9.2 0.2 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 CRK13310.1 - 6.4e-06 26.5 16.1 0.16 12.7 0.1 8.2 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 CRK13310.1 - 2.1e-05 24.2 5.9 0.2 11.8 0.0 6.2 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 CRK13310.1 - 0.00018 21.9 12.1 4.9 7.7 0.0 6.9 7 1 0 7 7 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 CRK13310.1 - 0.00063 19.9 0.0 12 6.5 0.0 5.4 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CRK13310.1 - 0.0018 18.4 8.8 0.12 12.6 0.8 5.6 5 1 2 7 7 6 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF3856 PF12968.7 CRK13310.1 - 0.0063 16.6 1.0 0.57 10.2 0.1 3.1 1 1 1 2 2 2 1 Domain of Unknown Function (DUF3856) ChAPs PF09295.10 CRK13310.1 - 0.05 12.6 0.0 3.7 6.4 0.0 2.2 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) DUF4810 PF16068.5 CRK13310.1 - 0.075 13.6 0.1 15 6.2 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4810) Exonuc_VII_S PF02609.16 CRK13310.1 - 0.076 13.1 0.3 18 5.5 0.2 3.1 2 0 0 2 2 2 0 Exonuclease VII small subunit TPR_10 PF13374.6 CRK13310.1 - 0.13 12.2 8.6 12 6.0 0.0 5.7 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_MalT PF17874.1 CRK13310.1 - 0.15 11.4 7.7 0.049 13.0 0.6 3.3 5 0 0 5 5 5 0 MalT-like TPR region Say1_Mug180 PF10340.9 CRK13310.1 - 0.16 10.8 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase DUF756 PF05506.12 CRK13314.1 - 0.084 13.8 0.1 0.15 13.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF756) Vps54 PF07928.12 CRK13315.1 - 4.5e-52 176.0 1.6 1.2e-51 174.6 0.0 2.6 3 0 0 3 3 3 1 Vps54-like protein Vps54_N PF10475.9 CRK13315.1 - 7.5e-08 32.0 0.6 2e-07 30.6 0.6 1.6 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex DUF5364 PF17322.2 CRK13315.1 - 0.0015 18.9 0.7 0.0049 17.2 0.1 2.2 2 0 0 2 2 2 1 Family of unknown function (DUF5364) FerA PF08165.11 CRK13315.1 - 0.025 14.5 1.1 0.025 14.5 1.1 2.5 3 0 0 3 3 3 0 FerA (NUC095) domain FliJ PF02050.16 CRK13315.1 - 0.048 13.9 0.2 0.21 11.8 0.2 2.1 1 0 0 1 1 1 0 Flagellar FliJ protein COG2 PF06148.11 CRK13315.1 - 0.11 12.6 1.3 0.47 10.6 0.4 2.5 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Sec8_exocyst PF04048.14 CRK13315.1 - 0.2 11.6 1.1 0.74 9.7 0.2 2.4 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain MCM PF00493.23 CRK13316.1 - 2.6e-105 350.5 0.2 7.5e-105 349.0 0.1 1.7 2 0 0 2 2 2 1 MCM P-loop domain MCM_lid PF17855.1 CRK13316.1 - 1.6e-27 95.8 1.2 3.8e-27 94.5 1.2 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CRK13316.1 - 6.8e-12 45.9 1.7 2e-11 44.4 1.7 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 CRK13316.1 - 7.4e-07 28.8 0.0 0.00014 21.3 0.0 2.4 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CRK13316.1 - 5.2e-06 26.5 0.0 3.1e-05 24.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 CRK13316.1 - 0.00039 20.3 0.0 0.0011 18.8 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CRK13316.1 - 0.029 14.1 0.0 0.8 9.4 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.29 CRK13316.1 - 0.058 13.8 0.2 0.19 12.1 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Rox3 PF08633.10 CRK13317.1 - 1.7e-50 172.2 0.8 2.5e-50 171.6 0.2 1.6 2 0 0 2 2 2 1 Rox3 mediator complex subunit TSGP1 PF07771.11 CRK13317.1 - 9.9 6.3 8.1 4 7.6 1.2 2.4 2 0 0 2 2 2 0 Tick salivary peptide group 1 DUF676 PF05057.14 CRK13318.1 - 7.3e-07 28.9 0.0 1.4e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 CRK13318.1 - 2.1e-05 24.4 0.1 0.00014 21.6 0.1 2.0 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 CRK13318.1 - 0.00055 20.6 2.8 0.00055 20.6 2.8 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 CRK13318.1 - 0.0033 17.3 0.0 0.0059 16.5 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 CRK13318.1 - 0.0039 16.5 0.0 0.0088 15.3 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 CRK13318.1 - 0.14 12.0 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold UPF0227 PF05728.12 CRK13318.1 - 0.16 11.9 0.1 0.33 10.8 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Thioesterase PF00975.20 CRK13318.1 - 0.23 11.6 4.3 0.26 11.3 0.0 2.4 2 0 0 2 2 2 0 Thioesterase domain SRP-alpha_N PF04086.13 CRK13318.1 - 1.7 8.5 24.6 3.8 7.4 24.6 1.6 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Syndecan PF01034.20 CRK13319.1 - 0.023 14.6 0.1 0.052 13.5 0.1 1.5 1 0 0 1 1 1 0 Syndecan domain DPPIV_N PF00930.21 CRK13321.1 - 4.4e-33 114.5 0.1 4.8e-33 114.4 0.1 1.0 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region MOSC_N PF03476.16 CRK13321.1 - 0.048 13.5 0.0 1.6 8.7 0.0 2.1 2 0 0 2 2 2 0 MOSC N-terminal beta barrel domain Glyoxal_oxid_N PF07250.11 CRK13350.1 - 0.018 14.2 0.0 0.021 14.1 0.0 1.1 1 0 0 1 1 1 0 Glyoxal oxidase N-terminus MmgE_PrpD PF03972.14 CRK13366.1 - 4.9e-29 101.1 0.1 5.4e-29 101.0 0.1 1.0 1 0 0 1 1 1 1 MmgE/PrpD family DUF3533 PF12051.8 CRK13369.1 - 1.1e-118 396.4 15.1 1.4e-118 396.1 15.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) DUF4714 PF15833.5 CRK13369.1 - 0.1 12.5 0.3 0.22 11.5 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4714) WBP-1 PF11669.8 CRK13369.1 - 0.21 12.2 1.0 0.45 11.2 0.0 2.0 2 0 0 2 2 2 0 WW domain-binding protein 1 Pyr_redox_3 PF13738.6 CRK13370.1 - 2.5e-16 59.8 0.0 1.1e-13 51.2 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CRK13370.1 - 1.1e-12 47.9 0.0 4.4e-10 39.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 CRK13370.1 - 8.5e-11 41.0 0.0 8.1e-09 34.4 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 CRK13370.1 - 8.8e-08 31.7 0.1 1.4e-05 24.5 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 CRK13370.1 - 0.00017 21.7 0.0 0.0013 18.9 0.0 2.5 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 CRK13370.1 - 0.00027 20.3 0.2 0.0079 15.5 0.0 2.6 3 0 0 3 3 3 1 FAD binding domain Pyr_redox PF00070.27 CRK13370.1 - 0.00032 21.2 0.1 0.18 12.4 0.1 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 CRK13370.1 - 0.0039 17.1 0.2 0.37 10.7 0.0 2.2 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SnoaL_2 PF12680.7 CRK13370.1 - 0.0063 17.1 0.9 0.043 14.5 0.0 2.6 3 0 0 3 3 3 1 SnoaL-like domain 2-Hacid_dh_C PF02826.19 CRK13370.1 - 0.017 14.5 0.1 0.22 10.9 0.0 2.4 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.14 CRK13370.1 - 0.09 11.5 0.0 0.51 9.0 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein ApbA PF02558.16 CRK13370.1 - 0.092 12.4 0.0 1.8 8.2 0.0 2.3 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 CRK13370.1 - 0.15 12.2 0.0 16 5.6 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase HHH_8 PF14716.6 CRK13370.1 - 0.15 12.4 0.0 7.7 7.0 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix domain TrkA_N PF02254.18 CRK13370.1 - 0.18 12.1 0.1 2.2 8.6 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain GIDA PF01134.22 CRK13370.1 - 0.19 10.8 0.7 5.6 5.9 0.0 2.7 3 0 0 3 3 3 0 Glucose inhibited division protein A Chromate_transp PF02417.15 CRK13371.1 - 3.3e-59 199.5 37.6 2e-33 115.8 16.0 2.8 3 0 0 3 3 3 2 Chromate transporter TRAPPC10 PF12584.8 CRK13372.1 - 5e-24 84.8 0.0 1.5e-23 83.2 0.0 1.9 2 0 0 2 2 2 1 Trafficking protein particle complex subunit 10, TRAPPC10 Foie-gras_1 PF11817.8 CRK13372.1 - 0.0034 17.0 0.2 0.0065 16.1 0.2 1.4 1 0 0 1 1 1 1 Foie gras liver health family 1 TPR_12 PF13424.6 CRK13372.1 - 0.15 12.3 1.0 0.53 10.6 0.9 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat IF-2B PF01008.17 CRK13373.1 - 4.9e-69 232.7 0.8 5.8e-69 232.4 0.8 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Peptidase_M20 PF01546.28 CRK13374.1 - 2.8e-22 79.5 5.9 5.7e-22 78.4 5.9 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CRK13374.1 - 3.1e-19 68.9 0.0 5.5e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 CRK13374.1 - 0.0049 16.6 0.0 0.0079 15.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Pkinase PF00069.25 CRK13375.1 - 9.4e-65 218.6 0.0 1.3e-64 218.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK13375.1 - 2.9e-41 141.5 0.0 4.1e-41 141.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CRK13375.1 - 3.9e-08 33.0 0.0 7.7e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CRK13375.1 - 2.3e-05 23.5 0.2 2.3e-05 23.5 0.2 1.8 3 0 0 3 3 3 1 Haspin like kinase domain APH PF01636.23 CRK13375.1 - 0.0096 15.9 1.2 0.032 14.2 0.1 2.2 2 1 1 3 3 3 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 CRK13375.1 - 0.041 12.9 0.0 0.064 12.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 CRK13375.1 - 0.042 13.2 0.0 0.098 12.0 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Prenyltrans PF00432.21 CRK13376.1 - 1.8e-30 104.3 11.4 4.1e-06 26.4 0.0 6.2 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 CRK13376.1 - 0.033 13.3 0.1 28 3.7 0.0 3.5 4 0 0 4 4 4 0 Squalene-hopene cyclase N-terminal domain Pkinase PF00069.25 CRK13377.1 - 3e-64 216.9 0.0 4.1e-64 216.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK13377.1 - 4.5e-41 140.9 0.0 6.4e-41 140.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CRK13377.1 - 3.2e-08 33.3 0.0 6.5e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CRK13377.1 - 1.9e-05 23.8 0.2 1.9e-05 23.8 0.2 1.8 3 0 0 3 3 3 1 Haspin like kinase domain APH PF01636.23 CRK13377.1 - 0.0069 16.3 1.1 0.027 14.4 0.1 2.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 CRK13377.1 - 0.035 13.5 0.0 0.084 12.2 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 CRK13377.1 - 0.036 13.1 0.0 0.056 12.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 CRK13377.1 - 0.18 11.4 0.1 0.54 9.8 0.1 1.8 2 0 0 2 2 2 0 RIO1 family Prenyltrans PF00432.21 CRK13378.1 - 8.2e-27 92.7 10.7 2e-05 24.2 0.0 6.0 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat DUF676 PF05057.14 CRK13378.1 - 1.7e-14 53.9 0.0 6.2e-06 25.9 0.0 2.5 2 0 0 2 2 2 2 Putative serine esterase (DUF676) NACHT PF05729.12 CRK13378.1 - 1.4e-11 44.6 4.8 5.1e-08 33.0 0.0 4.2 4 1 0 5 5 5 2 NACHT domain AAA_16 PF13191.6 CRK13378.1 - 2.9e-08 34.3 0.8 0.0025 18.2 0.0 4.3 5 0 0 5 5 5 2 AAA ATPase domain AAA_22 PF13401.6 CRK13378.1 - 5.9e-07 29.8 0.0 0.059 13.7 0.0 2.9 2 0 0 2 2 2 2 AAA domain Abhydrolase_9 PF10081.9 CRK13378.1 - 2.3e-06 26.9 0.1 0.059 12.4 0.0 2.6 2 0 0 2 2 2 2 Alpha/beta-hydrolase family AAA PF00004.29 CRK13378.1 - 3.6e-05 24.2 0.0 0.49 10.8 0.0 3.6 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 CRK13378.1 - 4.7e-05 23.7 0.0 0.57 10.6 0.0 2.6 2 0 0 2 2 2 2 RNA helicase Abhydrolase_6 PF12697.7 CRK13378.1 - 7.3e-05 23.5 0.1 1.1 9.9 0.0 3.2 3 0 0 3 3 3 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CRK13378.1 - 0.00014 21.2 0.1 0.79 8.9 0.0 3.0 3 0 0 3 3 3 2 Serine aminopeptidase, S33 Helicase_RecD PF05127.14 CRK13378.1 - 0.0094 15.8 0.0 1.9 8.3 0.0 2.5 2 0 0 2 2 2 1 Helicase Cutinase PF01083.22 CRK13378.1 - 0.01 15.8 0.0 7.3 6.5 0.0 2.4 2 0 0 2 2 2 0 Cutinase Zeta_toxin PF06414.12 CRK13378.1 - 0.014 14.7 0.0 4.3 6.6 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Ser_hydrolase PF06821.13 CRK13378.1 - 0.017 15.0 0.0 8.8 6.1 0.0 2.5 2 0 0 2 2 2 0 Serine hydrolase DUF2075 PF09848.9 CRK13378.1 - 0.15 11.3 0.0 15 4.7 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Ilm1 PF10311.9 CRK13379.1 - 1.3e-62 210.4 0.2 1.4e-62 210.2 0.2 1.0 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 Peptidase_A8 PF01252.18 CRK13379.1 - 0.13 12.5 2.3 0.88 9.8 0.2 2.4 1 1 0 2 2 2 0 Signal peptidase (SPase) II DUF4345 PF14248.6 CRK13379.1 - 6.2 6.8 10.9 12 5.9 1.3 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4345) NatB_MDM20 PF09797.9 CRK13380.1 - 9.2e-50 169.7 0.0 3.6e-49 167.7 0.0 1.9 1 1 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit Bac_rhamnosid6H PF17389.2 CRK13380.1 - 0.088 12.0 0.2 5.5 6.1 0.0 2.3 2 0 0 2 2 2 0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Ilm1 PF10311.9 CRK13381.1 - 5.6e-38 130.2 0.2 6.8e-38 129.9 0.2 1.0 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 DUF4345 PF14248.6 CRK13381.1 - 3.4 7.6 7.6 8.1 6.4 1.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4345) Mu-like_Pro PF10123.9 CRK13382.1 - 0.28 10.7 13.5 0.46 10.0 13.5 1.3 1 0 0 1 1 1 0 Mu-like prophage I protein Fib_alpha PF08702.10 CRK13382.1 - 0.56 10.4 12.9 4.3 7.5 0.8 2.8 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Med2 PF11214.8 CRK13382.1 - 0.6 10.3 7.2 18 5.5 3.7 3.1 2 1 1 3 3 3 0 Mediator complex subunit 2 FlaC_arch PF05377.11 CRK13382.1 - 5.7 7.4 5.3 54 4.3 0.2 3.3 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Baculo_PEP_C PF04513.12 CRK13382.1 - 8.1 6.5 11.8 17 5.4 8.5 2.8 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF604 PF04646.12 CRK13384.1 - 5.9e-14 52.1 0.0 4.8e-12 45.8 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function, DUF604 Fringe PF02434.16 CRK13384.1 - 1.7e-07 31.0 0.0 2.9e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Fringe-like Guanylate_kin PF00625.21 CRK13385.1 - 3.5e-55 186.5 0.0 3.9e-55 186.4 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase RsgA_GTPase PF03193.16 CRK13385.1 - 7.6e-05 22.7 0.2 0.00017 21.5 0.1 1.7 1 1 0 1 1 1 1 RsgA GTPase AAA_18 PF13238.6 CRK13385.1 - 0.00032 21.3 0.5 0.0027 18.3 0.5 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CRK13385.1 - 0.00032 21.1 0.3 0.00092 19.6 0.3 1.8 1 1 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 CRK13385.1 - 0.00082 19.4 0.3 0.0059 16.7 0.3 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 CRK13385.1 - 0.004 17.7 0.3 0.0073 16.8 0.3 1.9 1 1 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 CRK13385.1 - 0.007 16.6 0.2 0.022 15.0 0.1 1.7 2 1 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 CRK13385.1 - 0.034 14.0 0.1 0.059 13.3 0.1 1.4 1 0 0 1 1 1 0 NTPase NACHT PF05729.12 CRK13385.1 - 0.045 13.7 0.1 0.093 12.6 0.1 1.5 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.6 CRK13385.1 - 0.051 13.8 0.6 0.12 12.6 0.3 1.8 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 CRK13385.1 - 0.052 13.5 0.0 0.07 13.0 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_29 PF13555.6 CRK13385.1 - 0.055 13.2 0.1 0.12 12.1 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain dNK PF01712.19 CRK13385.1 - 0.061 13.2 0.8 1.9 8.3 0.8 2.3 1 1 0 1 1 1 0 Deoxynucleoside kinase AAA_33 PF13671.6 CRK13385.1 - 0.2 11.8 1.0 1.5 9.0 1.0 2.2 1 1 0 1 1 1 0 AAA domain Glyco_hydro_61 PF03443.14 CRK13386.1 - 5.1e-51 173.5 0.0 9.3e-51 172.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Fungal_trans PF04082.18 CRK13387.1 - 4.2e-08 32.5 0.0 6.7e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4148 PF13663.6 CRK13387.1 - 0.063 13.5 2.7 0.31 11.3 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) LigB PF02900.18 CRK13388.1 - 7.5e-31 107.2 0.0 1e-30 106.8 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Fungal_trans_2 PF11951.8 CRK13388.1 - 0.099 11.4 0.2 0.18 10.6 0.2 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK13388.1 - 0.36 11.0 1.8 0.6 10.3 1.8 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain RabGAP-TBC PF00566.18 CRK13389.1 - 4.6e-26 91.8 0.0 6.4e-26 91.3 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SBE2 PF17076.5 CRK13389.1 - 5.1e-07 28.3 1.1 7.6e-07 27.8 1.1 1.1 1 0 0 1 1 1 1 SBE2, cell-wall formation eIF2A PF08662.11 CRK13390.1 - 4.4e-37 127.9 3.8 1.6e-35 122.8 0.2 4.0 3 2 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 CRK13390.1 - 0.02 14.7 0.0 0.045 13.6 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 CRK13390.1 - 0.29 12.1 6.2 1.8 9.6 0.1 4.4 5 0 0 5 5 5 0 WD domain, G-beta repeat Cpn60_TCP1 PF00118.24 CRK13391.1 - 7.5e-144 480.0 11.5 8.6e-144 479.8 11.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF5442 PF17514.2 CRK13391.1 - 0.0097 16.1 0.2 0.023 14.9 0.2 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5442) Ribosomal_L20 PF00453.18 CRK13391.1 - 0.059 13.5 0.0 0.16 12.1 0.0 1.8 1 0 0 1 1 1 0 Ribosomal protein L20 CRM1_repeat PF18777.1 CRK13391.1 - 0.1 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat FlgM PF04316.13 CRK13391.1 - 0.21 12.0 2.1 5.1 7.5 0.0 3.4 3 0 0 3 3 3 0 Anti-sigma-28 factor, FlgM FA_desaturase PF00487.24 CRK13392.1 - 5.4e-24 85.4 23.8 1.2e-23 84.2 23.8 1.6 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 CRK13392.1 - 1.4e-07 31.8 0.0 4e-07 30.3 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3474) Aspzincin_M35 PF14521.6 CRK13394.1 - 3e-14 53.8 0.8 4.8e-12 46.6 0.7 2.0 1 1 1 2 2 2 2 Lysine-specific metallo-endopeptidase Peptidase_M35 PF02102.15 CRK13394.1 - 1.6e-07 30.6 2.0 4.7e-07 29.0 0.6 1.9 1 1 1 2 2 2 1 Deuterolysin metalloprotease (M35) family Ribonuc_2-5A PF06479.12 CRK13395.1 - 6.2e-43 146.0 0.0 1.3e-42 144.9 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.25 CRK13395.1 - 4.6e-40 137.7 0.0 4.9e-38 131.0 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK13395.1 - 2.2e-20 73.1 0.0 1e-18 67.6 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.21 CRK13395.1 - 0.00034 20.4 0.1 0.44 10.6 0.0 3.7 3 0 0 3 3 3 1 PQQ enzyme repeat PQQ_2 PF13360.6 CRK13395.1 - 0.0011 18.6 0.4 0.069 12.7 0.1 2.8 2 1 0 2 2 2 1 PQQ-like domain Kdo PF06293.14 CRK13395.1 - 0.0018 17.6 0.0 0.0035 16.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CRK13395.1 - 0.0033 16.3 0.0 0.0033 16.3 0.0 1.9 3 0 0 3 3 3 1 Fungal protein kinase APH PF01636.23 CRK13395.1 - 0.0084 16.1 0.0 0.0084 16.1 0.0 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF2946 PF11162.8 CRK13395.1 - 0.19 12.4 1.7 0.77 10.4 1.7 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) SEEEED PF14797.6 CRK13395.1 - 0.41 10.8 11.8 1 9.5 11.8 1.6 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex SR-25 PF10500.9 CRK13395.1 - 2.5 7.7 15.7 0.41 10.2 10.6 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein SWIB PF02201.18 CRK13396.1 - 9.9e-29 99.0 0.1 2.6e-28 97.7 0.1 1.8 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.11 CRK13396.1 - 1.1e-15 57.3 1.3 3e-15 55.9 1.1 1.9 2 0 0 2 2 2 1 DEK C terminal domain zf-C3HC4_3 PF13920.6 CRK13396.1 - 5.8e-06 26.1 8.2 5.8e-06 26.1 8.2 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CRK13396.1 - 0.00055 19.7 12.1 0.00055 19.7 12.1 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) W_rich_C PF07483.11 CRK13398.1 - 0.073 13.2 0.0 1.4 9.1 0.0 2.3 2 0 0 2 2 2 0 Tryptophan-rich Synechocystis species C-terminal domain Trypsin_2 PF13365.6 CRK13398.1 - 0.14 13.0 0.0 1.9 9.3 0.0 2.3 1 1 0 1 1 1 0 Trypsin-like peptidase domain ADH_zinc_N_2 PF13602.6 CRK13399.1 - 5.7e-28 98.6 0.1 1.5e-27 97.3 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 CRK13399.1 - 1.5e-15 57.4 0.6 2.3e-15 56.7 0.6 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TRAPPC-Trs85 PF12739.7 CRK13400.1 - 4.1e-115 385.0 0.0 9.5e-115 383.8 0.0 1.5 2 0 0 2 2 2 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Bud13 PF09736.9 CRK13401.1 - 8.2e-48 162.5 9.6 8.2e-48 162.5 9.6 2.0 3 1 0 3 3 3 1 Pre-mRNA-splicing factor of RES complex TFIIF_alpha PF05793.12 CRK13402.1 - 2.8e-07 29.5 49.4 2.8e-07 29.5 49.4 2.4 1 1 1 2 2 2 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PAP_assoc PF03828.19 CRK13403.1 - 2e-17 63.2 0.0 5e-17 61.9 0.0 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 CRK13403.1 - 0.001 19.3 0.0 0.0024 18.1 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF4924 PF16271.5 CRK13403.1 - 0.16 11.9 0.2 0.34 10.9 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4924) Pribosyltran_N PF13793.6 CRK13405.1 - 1.3e-43 147.6 0.1 5.9e-42 142.3 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 CRK13405.1 - 2.9e-34 118.7 0.1 2.6e-28 99.3 0.0 2.3 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 CRK13405.1 - 4.2e-10 39.4 0.1 9e-05 22.0 0.0 2.5 2 0 0 2 2 2 2 Phosphoribosyl transferase domain XPG_I_2 PF12813.7 CRK13406.1 - 1.1e-54 185.5 0.0 2.1e-54 184.6 0.0 1.5 1 0 0 1 1 1 1 XPG domain containing Mob1_phocein PF03637.17 CRK13408.1 - 1.4e-41 142.3 0.0 3.9e-39 134.4 0.0 2.5 1 1 0 1 1 1 1 Mob1/phocein family PAGK PF15284.6 CRK13408.1 - 0.062 13.2 0.2 0.37 10.7 0.0 2.3 2 0 0 2 2 2 0 Phage-encoded virulence factor CSN5_C PF18323.1 CRK13409.1 - 0.041 14.8 0.0 0.097 13.6 0.0 1.6 1 1 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain Pex14_N PF04695.13 CRK13409.1 - 6 7.5 13.1 1.9 9.1 2.6 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Peptidase_C12 PF01088.21 CRK13410.1 - 3.3e-55 187.1 0.0 3.9e-55 186.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 DEC-1_N PF04625.13 CRK13411.1 - 0.49 9.3 3.0 0.72 8.8 3.0 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region CFEM PF05730.11 CRK13412.1 - 8e-05 22.7 3.1 0.00019 21.4 3.1 1.6 1 0 0 1 1 1 1 CFEM domain DUF872 PF05915.12 CRK13412.1 - 1.3 9.2 3.3 4.2 7.6 0.1 2.7 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) UPF0052 PF01933.18 CRK13413.1 - 5.9e-60 203.0 0.0 7.4e-60 202.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 Cut8 PF08559.10 CRK13416.1 - 7.1e-31 107.7 0.1 7.6e-31 107.6 0.1 1.0 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein Glyco_transf_90 PF05686.12 CRK13419.1 - 0.021 13.8 0.0 0.021 13.8 0.0 1.0 1 0 0 1 1 1 0 Glycosyl transferase family 90 Fungal_trans PF04082.18 CRK13471.1 - 9e-09 34.7 0.3 3.1e-08 33.0 0.3 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK13471.1 - 3.3e-07 30.3 11.2 6e-07 29.5 11.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UQ_con PF00179.26 CRK13472.1 - 1.1e-10 41.3 0.0 1.7e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme HeLo PF14479.6 CRK13473.1 - 1.6e-14 54.3 0.4 3e-14 53.3 0.4 1.4 1 0 0 1 1 1 1 Prion-inhibition and propagation Pkinase PF00069.25 CRK13473.1 - 1.4e-07 31.2 0.0 2.3e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK13473.1 - 2.8e-06 26.8 0.0 5.1e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.7 CRK13475.1 - 8.5e-37 125.6 0.2 4.5e-10 40.0 0.2 6.1 4 2 1 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CRK13475.1 - 3.6e-30 103.9 6.3 4.5e-10 39.9 0.0 9.0 6 3 3 10 10 10 7 Ankyrin repeats (many copies) Ank PF00023.30 CRK13475.1 - 4.4e-28 96.4 10.3 0.00068 20.0 0.0 9.2 8 0 0 8 8 8 6 Ankyrin repeat Ank_3 PF13606.6 CRK13475.1 - 1.5e-27 92.5 6.2 0.00087 19.6 0.1 9.2 9 0 0 9 9 9 7 Ankyrin repeat Pkinase PF00069.25 CRK13475.1 - 1.5e-23 83.5 0.0 2.3e-23 82.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ank_5 PF13857.6 CRK13475.1 - 4.3e-22 77.9 6.9 0.00014 22.0 0.0 7.4 7 0 0 7 7 7 5 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 CRK13475.1 - 6.6e-20 71.5 0.0 1.1e-19 70.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF294 PF03445.13 CRK13475.1 - 0.014 15.2 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 Putative nucleotidyltransferase DUF294 EccE PF11203.8 CRK13475.1 - 0.092 13.1 0.2 1.2 9.5 0.3 2.6 2 0 0 2 2 2 0 Putative type VII ESX secretion system translocon, EccE NO_synthase PF02898.15 CRK13476.1 - 0.05 12.6 0.0 0.07 12.2 0.0 1.1 1 0 0 1 1 1 0 Nitric oxide synthase, oxygenase domain CYSTM PF12734.7 CRK13478.1 - 1.6e-09 37.9 6.7 1.6e-09 37.9 6.7 4.2 3 1 0 3 3 3 1 Cysteine-rich TM module stress tolerance RSN1_7TM PF02714.15 CRK13479.1 - 2.8e-151 502.4 46.0 3.7e-76 256.1 19.1 2.6 2 0 0 2 2 2 2 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 CRK13479.1 - 1.2e-58 198.2 6.0 2.7e-16 60.3 0.1 4.7 4 0 0 4 4 4 4 Cytosolic domain of 10TM putative phosphate transporter NTP_transf_9 PF04248.12 CRK13479.1 - 5.2e-54 180.1 5.8 2.6e-26 91.3 0.6 2.9 2 0 0 2 2 2 2 Domain of unknown function (DUF427) RSN1_TM PF13967.6 CRK13479.1 - 2.7e-51 173.4 10.5 1.2e-47 161.6 0.1 4.3 5 0 0 5 5 5 2 Late exocytosis, associated with Golgi transport PHM7_ext PF12621.8 CRK13479.1 - 4.2e-24 84.5 0.0 1.8e-10 40.8 0.0 2.8 2 0 0 2 2 2 2 Extracellular tail, of 10TM putative phosphate transporter DUF2635 PF10948.8 CRK13479.1 - 0.14 11.9 0.1 34 4.3 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2635) RcsC PF09456.10 CRK13479.1 - 0.24 11.4 3.0 22 5.1 0.2 3.1 2 0 0 2 2 2 0 RcsC Alpha-Beta-Loop (ABL) DUF383 PF04063.14 CRK13480.1 - 4.4e-67 225.4 0.2 1.1e-65 220.9 0.0 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.13 CRK13480.1 - 7.9e-23 80.1 0.4 2.7e-22 78.4 0.4 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF384) LMSTEN PF07988.12 CRK13480.1 - 0.039 13.4 0.1 0.099 12.1 0.1 1.6 1 0 0 1 1 1 0 LMSTEN motif BESS PF02944.20 CRK13480.1 - 0.15 11.9 0.5 0.46 10.4 0.5 1.9 1 0 0 1 1 1 0 BESS motif Bystin PF05291.11 CRK13481.1 - 4.4e-123 410.2 0.0 6.8e-123 409.6 0.0 1.2 1 0 0 1 1 1 1 Bystin DUF89 PF01937.19 CRK13484.1 - 3.3e-134 447.3 0.0 3.8e-134 447.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 FMN_dh PF01070.18 CRK13486.1 - 3.2e-83 279.6 0.1 1.1e-79 268.0 0.1 2.0 1 1 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 CRK13486.1 - 2e-06 27.1 0.3 2e-05 23.8 0.0 2.3 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 CRK13486.1 - 0.00073 18.8 0.2 0.0017 17.6 0.2 1.6 1 1 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 CRK13486.1 - 0.0094 15.4 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase Peptidase_M19 PF01244.21 CRK13486.1 - 0.01 15.0 0.0 0.087 12.0 0.0 2.0 1 1 0 1 1 1 0 Membrane dipeptidase (Peptidase family M19) ATP-synt_D PF01813.17 CRK13486.1 - 0.02 14.7 0.4 0.031 14.1 0.4 1.2 1 0 0 1 1 1 0 ATP synthase subunit D ESAG1 PF03238.13 CRK13486.1 - 0.14 11.6 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 ESAG protein Pec_lyase_C PF00544.19 CRK13487.1 - 7.4e-12 45.3 8.6 3.3e-10 39.9 8.6 2.3 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 CRK13487.1 - 2e-05 24.5 16.7 0.007 16.2 3.4 2.5 1 1 0 2 2 2 2 Right handed beta helix region Phage_attach PF05354.11 CRK13487.1 - 0.24 11.3 2.7 0.37 10.7 0.1 2.4 3 0 0 3 3 3 0 Phage Head-Tail Attachment CN_hydrolase PF00795.22 CRK13488.1 - 4.2e-24 85.3 0.0 1.5e-21 76.9 0.0 2.5 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase Synaptobrevin PF00957.21 CRK13491.1 - 4.5e-32 109.7 0.3 6.8e-32 109.1 0.3 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 CRK13491.1 - 7.7e-29 99.6 0.0 1.5e-28 98.6 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain SUV3_C PF12513.8 CRK13492.1 - 2e-16 59.6 0.3 4.3e-16 58.6 0.3 1.6 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 CRK13492.1 - 5.3e-10 39.6 0.0 1.6e-09 38.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Suv3_C_1 PF18147.1 CRK13492.1 - 1.4e-07 31.2 0.2 4.1e-07 29.8 0.1 1.9 2 0 0 2 2 2 1 Suv3 C-terminal domain 1 Mob1_phocein PF03637.17 CRK13493.1 - 2.8e-44 151.1 0.0 6.3e-44 150.0 0.0 1.5 1 1 0 1 1 1 1 Mob1/phocein family PAGK PF15284.6 CRK13493.1 - 0.065 13.1 0.1 0.34 10.9 0.0 2.2 2 0 0 2 2 2 0 Phage-encoded virulence factor XPG_I_2 PF12813.7 CRK13495.1 - 1.8e-54 184.9 0.0 3e-54 184.1 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing Pribosyltran_N PF13793.6 CRK13496.1 - 1.2e-43 147.7 0.1 5.5e-42 142.4 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 CRK13496.1 - 2.5e-34 118.9 0.1 2.4e-28 99.4 0.0 2.3 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 CRK13496.1 - 3.9e-10 39.5 0.1 8.2e-05 22.2 0.0 2.5 2 0 0 2 2 2 2 Phosphoribosyl transferase domain PAP_assoc PF03828.19 CRK13498.1 - 2e-17 63.2 0.0 6.6e-17 61.5 0.0 2.0 1 1 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 CRK13498.1 - 0.00089 19.5 0.0 0.0024 18.1 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain TFIIF_alpha PF05793.12 CRK13499.1 - 3.2e-09 35.9 55.7 6.3e-09 35.0 55.7 1.6 1 1 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Bud13 PF09736.9 CRK13500.1 - 1.7e-47 161.4 10.6 1.7e-47 161.4 10.6 1.9 3 0 0 3 3 3 1 Pre-mRNA-splicing factor of RES complex TRAPPC-Trs85 PF12739.7 CRK13501.1 - 5.3e-116 387.9 0.0 2e-115 386.0 0.0 1.7 2 0 0 2 2 2 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit ADH_zinc_N_2 PF13602.6 CRK13502.1 - 1.8e-27 97.0 0.1 3.8e-27 95.9 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 CRK13502.1 - 7.5e-15 55.1 0.3 7.5e-15 55.1 0.3 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Vps26 PF03643.15 CRK13503.1 - 8.7e-76 254.5 1.4 9.6e-76 254.4 1.4 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Cyclin_N PF00134.23 CRK13506.1 - 1.7e-10 40.8 0.0 2.4e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 CRK13506.1 - 0.00012 22.5 0.0 0.0002 21.8 0.0 1.4 1 0 0 1 1 1 1 Cyclin RRM_2 PF04059.12 CRK13547.1 - 3e-38 129.9 0.4 5.5e-38 129.1 0.4 1.5 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 CRK13547.1 - 0.0001 22.0 0.0 0.32 10.8 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sad1_UNC PF07738.13 CRK13548.1 - 3.1e-31 108.1 0.0 5.2e-31 107.4 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal RGS12_usC PF16612.5 CRK13549.1 - 2.5 8.5 7.6 20 5.6 4.8 2.5 2 0 0 2 2 2 0 C-terminal unstructured region of RGS12 Not1 PF04054.15 CRK13550.1 - 7.5e-110 367.3 0.0 1.7e-109 366.1 0.0 1.6 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 CRK13550.1 - 1.4e-90 302.6 0.7 3e-90 301.5 0.7 1.5 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 CRK13550.1 - 5.2e-50 169.2 0.7 2.1e-49 167.2 0.7 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 CRK13550.1 - 2.8e-42 144.1 0.0 9.2e-42 142.4 0.0 1.8 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 CRK13550.1 - 1.1e-36 126.1 0.5 1.1e-36 126.1 0.5 2.1 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 HEAT repeat EPO_TPO PF00758.18 CRK13550.1 - 0.086 12.9 0.1 0.24 11.4 0.1 1.7 1 0 0 1 1 1 0 Erythropoietin/thrombopoietin Seipin PF06775.14 CRK13551.1 - 6.8e-55 186.2 0.6 1.1e-54 185.6 0.6 1.3 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) FCH PF00611.23 CRK13551.1 - 1.4e-13 50.9 0.8 2.7e-13 50.0 0.1 1.9 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 CRK13551.1 - 4e-09 35.9 0.1 8e-09 35.0 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CRK13551.1 - 0.00021 21.1 0.1 0.00048 19.9 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CRK13551.1 - 0.00027 20.6 0.0 0.0015 18.2 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain NTF2 PF02136.20 CRK13553.1 - 1.5e-32 112.7 0.1 1.7e-32 112.5 0.1 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Circo_capsid PF02443.15 CRK13553.1 - 0.16 11.5 0.0 0.2 11.2 0.0 1.1 1 0 0 1 1 1 0 Circovirus capsid protein Ribosomal_L7Ae PF01248.26 CRK13554.1 - 2.2e-21 75.4 0.5 3.8e-21 74.6 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family MWFE PF15879.5 CRK13554.1 - 3.7e-20 71.8 0.0 7.3e-20 70.9 0.0 1.6 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit ATP_bind_3 PF01171.20 CRK13555.1 - 3.3e-17 62.8 0.0 6.1e-17 61.9 0.0 1.5 1 0 0 1 1 1 1 PP-loop family zn-ribbon_14 PF16503.5 CRK13555.1 - 5.3e-15 54.6 3.2 5.3e-15 54.6 3.2 4.0 4 0 0 4 4 4 2 Zinc-ribbon RecR PF02132.15 CRK13555.1 - 0.027 14.0 0.7 0.027 14.0 0.7 3.1 4 0 0 4 4 4 0 RecR protein zf-UBR PF02207.20 CRK13555.1 - 0.57 10.4 6.4 11 6.2 0.7 2.7 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) MU117 PF15474.6 CRK13555.1 - 0.94 10.3 6.2 1.4 9.7 1.3 2.9 3 0 0 3 3 3 0 Meiotically up-regulated gene family TF_Zn_Ribbon PF08271.12 CRK13555.1 - 8.9 5.9 8.9 1.9 8.1 0.2 3.3 3 0 0 3 3 3 0 TFIIB zinc-binding MOZ_SAS PF01853.18 CRK13557.1 - 1.2e-74 249.8 0.0 1.9e-74 249.2 0.0 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 CRK13557.1 - 1.2e-20 72.9 3.6 2.4e-20 71.9 3.6 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain PHD_4 PF16866.5 CRK13557.1 - 2.9e-05 24.1 1.4 9.4e-05 22.4 1.4 1.8 1 0 0 1 1 1 1 PHD-finger Acetyltransf_7 PF13508.7 CRK13557.1 - 0.15 12.5 0.0 0.32 11.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Prok-RING_1 PF14446.6 CRK13557.1 - 0.17 11.9 1.8 0.39 10.7 1.8 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD PF00628.29 CRK13557.1 - 0.7 9.8 8.2 0.22 11.5 4.2 2.1 2 0 0 2 2 2 0 PHD-finger PHY PF00360.20 CRK13558.1 - 4.6e-29 101.0 0.0 8.9e-29 100.1 0.0 1.4 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.26 CRK13558.1 - 1.3e-20 73.9 0.1 3.1e-20 72.7 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 CRK13558.1 - 3.5e-17 62.6 0.0 2.1e-16 60.1 0.0 2.3 1 1 0 1 1 1 1 Response regulator receiver domain GAF PF01590.26 CRK13558.1 - 6.4e-13 49.5 0.0 2.7e-12 47.5 0.0 2.1 1 0 0 1 1 1 1 GAF domain HisKA PF00512.25 CRK13558.1 - 2.1e-12 46.9 1.0 6.5e-12 45.3 0.5 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.11 CRK13558.1 - 7e-08 33.1 0.0 1.6e-07 32.0 0.0 1.7 1 0 0 1 1 1 1 PAS fold HATPase_c_3 PF13589.6 CRK13558.1 - 0.017 14.9 0.0 0.034 14.0 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 CRK13558.1 - 0.054 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 GHKL domain PAS_9 PF13426.7 CRK13558.1 - 0.1 12.9 0.0 0.28 11.5 0.0 1.7 1 0 0 1 1 1 0 PAS domain Mfa1 PF17445.2 CRK13558.1 - 2.7 8.1 6.9 9.5 6.3 3.5 3.3 2 0 0 2 2 2 0 Mating factor A1 Sec8_exocyst PF04048.14 CRK13559.1 - 0.00067 19.6 0.4 0.00087 19.2 0.4 1.2 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain DUF4165 PF13752.6 CRK13559.1 - 0.065 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4165) Sec15 PF04091.12 CRK13560.1 - 8.1e-101 337.6 9.8 1.2e-99 333.7 9.8 2.1 1 1 0 1 1 1 1 Exocyst complex subunit Sec15-like DUF3510 PF12022.8 CRK13560.1 - 0.024 15.0 0.3 0.76 10.2 0.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF3510) GIT_CC PF16559.5 CRK13560.1 - 0.16 11.9 2.3 14 5.6 1.5 2.5 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor CBFD_NFYB_HMF PF00808.23 CRK13561.1 - 1.1e-19 70.4 0.4 1.7e-19 69.8 0.4 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CRK13561.1 - 8.1e-15 55.3 0.1 1.6e-14 54.4 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 CRK13561.1 - 0.039 14.3 0.0 0.075 13.4 0.0 1.5 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Pol_alpha_B_N PF08418.10 CRK13561.1 - 0.045 13.7 0.0 0.066 13.2 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Fcf2 PF08698.11 CRK13562.1 - 1.7e-32 111.7 0.3 2.8e-32 111.0 0.3 1.4 1 0 0 1 1 1 1 Fcf2 pre-rRNA processing tRNA-synt_1b PF00579.25 CRK13563.1 - 1.6e-71 241.0 0.0 2e-71 240.7 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Xpo1 PF08389.12 CRK13564.1 - 4.1e-08 33.4 0.1 6.4e-07 29.5 0.0 3.0 3 0 0 3 3 3 1 Exportin 1-like protein Importin_rep_3 PF18806.1 CRK13564.1 - 0.014 15.5 0.0 0.11 12.6 0.0 2.6 2 0 0 2 2 2 0 Importin 13 repeat Importin_rep PF18773.1 CRK13564.1 - 0.016 14.9 0.3 0.56 9.9 0.0 3.1 3 0 0 3 3 3 0 Importin 13 repeat MMS19_C PF12460.8 CRK13564.1 - 2.9 6.9 5.3 4.6 6.2 1.6 2.8 3 1 0 3 3 3 0 RNAPII transcription regulator C-terminal Creatinase_N_2 PF16189.5 CRK13565.1 - 2.2e-50 170.9 0.0 1.1e-49 168.7 0.0 2.2 4 0 0 4 4 4 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 CRK13565.1 - 2e-41 142.0 0.0 2.7e-41 141.6 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 CRK13565.1 - 4.7e-20 72.6 0.1 5.7e-18 65.8 0.0 2.7 2 1 1 3 3 3 1 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 CRK13565.1 - 1.2e-19 70.1 1.0 3.6e-19 68.6 0.4 2.2 2 0 0 2 2 2 1 C-terminal region of peptidase_M24 DUF1335 PF07056.11 CRK13565.1 - 0.037 14.1 0.0 0.077 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1335) DER1 PF04511.15 CRK13567.1 - 1.7e-50 171.6 5.6 2e-50 171.4 5.6 1.0 1 0 0 1 1 1 1 Der1-like family ARD PF03079.14 CRK13568.1 - 1.8e-45 154.9 0.6 2.1e-45 154.7 0.6 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 CRK13568.1 - 1.7e-09 37.3 0.2 4e-09 36.1 0.1 1.6 2 0 0 2 2 2 1 Cupin domain AraC_binding PF02311.19 CRK13568.1 - 3.3e-07 30.3 0.1 4.5e-07 29.9 0.1 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Ribosomal_L29e PF01779.17 CRK13569.1 - 1.3e-17 63.8 9.1 1.1e-08 35.2 2.4 2.3 2 0 0 2 2 2 2 Ribosomal L29e protein family Peptidase_C2 PF00648.21 CRK13571.1 - 1.9e-26 92.8 0.0 8.4e-26 90.7 0.0 1.9 2 0 0 2 2 2 1 Calpain family cysteine protease Calpain_III PF01067.22 CRK13571.1 - 1.9e-11 44.4 0.0 5.7e-05 23.4 0.0 3.6 3 0 0 3 3 3 2 Calpain large subunit, domain III DUF5638 PF18688.1 CRK13571.1 - 0.18 12.2 0.1 0.34 11.2 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5638) MIT PF04212.18 CRK13571.1 - 0.18 11.9 0.9 0.37 10.9 0.9 1.5 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain zf-C2H2 PF00096.26 CRK13572.1 - 1.2e-07 31.8 10.0 0.0052 17.2 2.0 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CRK13572.1 - 0.017 15.9 7.9 0.11 13.4 1.7 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CRK13572.1 - 0.03 14.7 9.8 2.7 8.6 0.2 3.8 4 0 0 4 4 4 0 Zinc-finger double domain zf-Di19 PF05605.12 CRK13572.1 - 2.8 8.3 5.6 0.41 11.0 0.7 2.0 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF2985 PF11204.8 CRK13574.1 - 5.3e-36 122.6 0.5 9.7e-36 121.8 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) EamA PF00892.20 CRK13575.1 - 6.4e-10 39.3 23.7 0.00012 22.2 3.4 2.7 2 1 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 CRK13575.1 - 1.3e-07 31.1 1.1 2.1e-07 30.4 1.1 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.16 CRK13575.1 - 0.00053 19.4 0.2 0.00053 19.4 0.2 2.0 2 1 0 2 2 2 1 Triose-phosphate Transporter family DUF423 PF04241.15 CRK13575.1 - 0.035 14.3 5.2 0.76 10.0 0.8 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF423) CPP1-like PF11833.8 CRK13575.1 - 0.23 11.1 0.1 0.23 11.1 0.1 1.9 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like NAD_binding_6 PF08030.12 CRK13576.1 - 8.2e-22 78.0 0.0 6.2e-13 49.1 0.0 2.4 1 1 1 2 2 2 2 Ferric reductase NAD binding domain Yippee-Mis18 PF03226.14 CRK13576.1 - 5.4e-15 55.5 0.7 8.9e-15 54.8 0.7 1.3 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly FAD_binding_8 PF08022.12 CRK13576.1 - 5.1e-14 52.3 0.0 2e-12 47.1 0.0 2.5 1 1 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 CRK13576.1 - 0.00023 21.3 0.1 0.00078 19.6 0.0 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component SPOUT_MTase PF02590.17 CRK13576.1 - 0.025 14.6 0.0 0.051 13.6 0.0 1.4 1 0 0 1 1 1 0 Predicted SPOUT methyltransferase RIG-I_C-RD PF11648.8 CRK13576.1 - 0.088 13.0 0.8 0.17 12.1 0.8 1.4 1 0 0 1 1 1 0 C-terminal domain of RIG-I Ferric_reduct PF01794.19 CRK13577.1 - 1.4e-22 80.1 11.4 1.4e-22 80.1 11.4 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 CRK13577.1 - 1.7e-21 77.0 0.0 6.9e-13 49.0 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 CRK13577.1 - 1.4e-13 50.9 0.0 3.6e-12 46.3 0.0 2.3 1 1 0 1 1 1 1 FAD-binding domain SPOUT_MTase PF02590.17 CRK13577.1 - 0.007 16.4 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 Predicted SPOUT methyltransferase CLU PF13236.6 CRK13579.1 - 1.1e-74 251.0 0.0 2.3e-74 250.0 0.0 1.6 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 CRK13579.1 - 6.9e-54 182.5 0.5 1.8e-53 181.2 0.0 2.0 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 CRK13579.1 - 1.6e-26 92.4 4.3 7.2e-10 39.0 0.1 4.1 3 1 1 4 4 4 3 Tetratricopeptide repeat CLU_N PF15044.6 CRK13579.1 - 2.4e-23 82.3 0.1 2.4e-22 79.1 0.0 2.3 2 0 0 2 2 2 1 Mitochondrial function, CLU-N-term TPR_10 PF13374.6 CRK13579.1 - 2.7e-23 81.1 2.2 3e-07 30.1 0.0 5.3 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 CRK13579.1 - 0.00011 22.1 6.2 0.027 14.7 0.1 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat DUF727 PF05303.12 CRK13579.1 - 0.0023 17.9 0.0 0.0065 16.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF727) TPR_2 PF07719.17 CRK13579.1 - 0.0081 16.2 4.9 3.5 8.0 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat Hep_59 PF07052.11 CRK13579.1 - 1.2 9.9 8.0 0.096 13.5 1.5 2.5 2 0 0 2 2 2 0 Hepatocellular carcinoma-associated antigen 59 Tubulin_3 PF14881.6 CRK13582.1 - 4.8e-70 234.9 0.1 7.7e-70 234.3 0.1 1.3 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.9 CRK13582.1 - 3.4e-39 133.8 0.0 6.3e-39 132.9 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.25 CRK13582.1 - 6.7e-07 29.7 0.0 0.0086 16.3 0.0 2.2 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain PAP_central PF04928.17 CRK13583.1 - 4.9e-111 369.6 0.0 6.5e-111 369.2 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 CRK13583.1 - 1.9e-66 222.9 0.7 3.5e-66 222.0 0.0 1.8 2 0 0 2 2 2 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 CRK13583.1 - 3.3e-10 40.1 0.1 6.5e-10 39.2 0.1 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Peptidase_S49 PF01343.18 CRK13583.1 - 0.0085 16.1 0.1 0.017 15.1 0.1 1.4 1 0 0 1 1 1 1 Peptidase family S49 Nrap_D2 PF17403.2 CRK13583.1 - 0.02 14.7 0.1 0.13 12.1 0.1 2.3 2 1 0 2 2 2 0 Nrap protein PAP/OAS-like domain Polbeta PF18765.1 CRK13583.1 - 0.062 13.4 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Pkinase PF00069.25 CRK13584.1 - 5.3e-77 258.7 0.0 6.3e-77 258.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK13584.1 - 1.2e-37 129.6 0.0 1.7e-37 129.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CRK13584.1 - 0.00072 18.6 0.0 0.011 14.7 0.0 2.1 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CRK13584.1 - 0.023 14.0 0.1 0.046 13.1 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CRK13584.1 - 0.023 14.6 0.0 0.061 13.2 0.0 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 CRK13584.1 - 0.048 13.0 0.1 0.16 11.2 0.0 1.8 1 1 0 2 2 2 0 Kinase-like zf-RING_5 PF14634.6 CRK13585.1 - 4.9e-06 26.4 4.6 8.7e-06 25.6 4.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 CRK13585.1 - 1.2e-05 25.5 4.7 1.2e-05 25.5 4.7 1.7 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 CRK13585.1 - 8.9e-05 22.4 4.0 8.9e-05 22.4 4.0 1.9 2 0 0 2 2 2 1 RING-type zinc-finger FYVE PF01363.21 CRK13585.1 - 0.00016 21.7 1.8 0.00038 20.5 1.8 1.6 1 0 0 1 1 1 1 FYVE zinc finger zf-C3HC4_2 PF13923.6 CRK13585.1 - 0.00021 21.1 2.3 0.00067 19.4 2.3 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CRK13585.1 - 0.00021 21.1 4.4 0.00021 21.1 4.4 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CRK13585.1 - 0.0012 18.7 4.8 0.0028 17.5 4.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CRK13585.1 - 0.0066 16.6 2.1 0.0066 16.6 2.1 2.1 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING Rtf2 PF04641.12 CRK13585.1 - 0.0088 15.4 0.8 0.0088 15.4 0.8 2.2 2 0 0 2 2 2 1 Rtf2 RING-finger zf-RING_10 PF16685.5 CRK13585.1 - 0.016 15.3 3.6 0.22 11.7 1.7 2.5 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-AD PF07776.15 CRK13585.1 - 0.18 12.1 3.0 2.9 8.2 0.1 2.6 1 1 1 2 2 2 0 Zinc-finger associated domain (zf-AD) zf-Nse PF11789.8 CRK13585.1 - 0.45 10.4 5.4 0.34 10.7 2.1 2.2 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_5 PF17121.5 CRK13585.1 - 1.3 9.0 8.4 0.11 12.4 3.6 1.8 2 0 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CRK13585.1 - 5 7.1 11.6 11 6.0 8.4 2.9 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 CRK13585.1 - 7.3 6.5 7.6 2.7 7.8 4.7 1.8 2 0 0 2 2 1 0 RING/Ubox like zinc-binding domain SCA7 PF08313.12 CRK13586.1 - 5.1e-31 106.4 0.1 1.9e-30 104.5 0.1 2.0 1 0 0 1 1 1 1 SCA7, zinc-binding domain Copper-fist PF00649.18 CRK13586.1 - 9.2e-22 76.3 1.9 9.2e-22 76.3 1.9 4.1 1 1 3 4 4 4 1 Copper fist DNA binding domain ApbA_C PF08546.11 CRK13586.1 - 2.5e-21 76.2 0.0 4.3e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal CDC45 PF02724.14 CRK13586.1 - 0.0067 14.8 1.9 0.0089 14.4 1.9 1.1 1 0 0 1 1 1 1 CDC45-like protein Sugar_tr PF00083.24 CRK13588.1 - 4.9e-17 61.9 1.3 4.9e-17 61.9 1.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter TPR_4 PF07721.14 CRK13588.1 - 0.00021 21.6 1.6 0.00038 20.8 1.6 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 CRK13588.1 - 0.0017 18.2 0.4 0.0034 17.3 0.4 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 CRK13588.1 - 0.0049 17.1 0.4 0.0076 16.5 0.4 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 CRK13588.1 - 0.0056 16.7 0.3 0.01 15.9 0.3 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 CRK13588.1 - 0.0098 15.7 0.1 0.02 14.7 0.1 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 CRK13588.1 - 0.011 16.5 0.5 0.025 15.4 0.5 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.6 CRK13588.1 - 0.025 15.1 0.9 0.043 14.3 0.9 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_10 PF13374.6 CRK13588.1 - 0.041 13.8 0.2 0.041 13.8 0.2 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Shikimate_DH PF01488.20 CRK13593.1 - 0.0036 17.4 0.0 0.0047 17.0 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.6 CRK13593.1 - 0.035 13.4 0.0 0.035 13.3 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 CRK13593.1 - 0.042 13.2 0.0 0.074 12.4 0.0 1.5 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 CRK13593.1 - 0.096 13.1 0.0 0.12 12.8 0.0 1.4 1 1 0 1 1 1 0 Putative NAD(P)-binding HisG_C PF08029.11 CRK13595.1 - 2.3e-28 98.1 0.2 3.3e-28 97.6 0.2 1.2 1 0 0 1 1 1 1 HisG, C-terminal domain eRF1_2 PF03464.15 CRK13619.1 - 1.3e-45 154.9 0.0 3.4e-45 153.6 0.0 1.7 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 CRK13619.1 - 2.8e-39 134.1 0.6 8.4e-39 132.6 0.6 1.9 1 0 0 1 1 1 1 eRF1 domain 3 Sybindin PF04099.12 CRK13619.1 - 5.5e-13 49.1 0.0 1.4e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 Sybindin-like family eRF1_1 PF03463.15 CRK13619.1 - 2.1e-09 37.5 0.8 2.3e-08 34.1 0.0 2.4 2 0 0 2 2 2 1 eRF1 domain 1 acVLRF1 PF18859.1 CRK13619.1 - 3.6e-08 33.7 0.0 3.6e-08 33.7 0.0 2.5 2 1 0 2 2 2 1 Actinobacteria/chloroflexi VLRF1 release factor FAA_hydrolase_N PF09298.11 CRK13619.1 - 1.5 9.1 4.5 2.9 8.1 3.4 2.0 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal 3Beta_HSD PF01073.19 CRK13635.1 - 0.00011 21.3 0.0 0.00014 21.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 CRK13635.1 - 0.18 11.2 0.0 0.3 10.4 0.0 1.5 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase ATP19 PF11022.8 CRK13639.1 - 3.3e-12 46.6 0.0 3.4e-12 46.5 0.0 1.0 1 0 0 1 1 1 1 ATP synthase subunit K Fungal_trans PF04082.18 CRK13645.1 - 1.1e-09 37.7 0.0 1.8e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4306 PF14154.6 CRK13645.1 - 0.11 12.7 0.1 0.18 12.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4306) Peptidase_S8 PF00082.22 CRK13646.1 - 3.1e-17 62.8 0.0 1.6e-16 60.4 0.0 1.9 1 1 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 CRK13646.1 - 5.3e-06 27.1 0.0 1.3e-05 25.8 0.0 1.7 1 1 0 1 1 1 1 Fn3-like domain LUC7 PF03194.15 CRK13647.1 - 6.9e-70 235.6 0.8 8.3e-70 235.3 0.8 1.0 1 0 0 1 1 1 1 LUC7 N_terminus Imm49 PF15575.6 CRK13647.1 - 0.02 14.6 0.1 0.04 13.7 0.1 1.4 1 0 0 1 1 1 0 Immunity protein 49 DUF1241 PF06840.11 CRK13647.1 - 0.052 13.2 0.1 0.11 12.2 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1241) T4SS PF07996.11 CRK13647.1 - 0.13 12.7 0.1 0.13 12.7 0.1 1.4 2 0 0 2 2 2 0 Type IV secretion system proteins TFIIA PF03153.13 CRK13648.1 - 1.4 8.8 13.0 1.9 8.4 13.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hamartin PF04388.12 CRK13648.1 - 4.8 5.7 12.1 6.1 5.4 12.1 1.1 1 0 0 1 1 1 0 Hamartin protein F-box-like PF12937.7 CRK13649.1 - 0.00084 19.2 0.1 0.0013 18.6 0.1 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CRK13649.1 - 0.0015 18.4 0.2 0.0026 17.6 0.2 1.4 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 CRK13649.1 - 0.16 11.9 0.1 0.22 11.4 0.1 1.2 1 0 0 1 1 1 0 F-box PRANC PF09372.10 CRK13649.1 - 0.24 11.7 0.0 0.33 11.3 0.0 1.1 1 0 0 1 1 1 0 PRANC domain LAMTOR PF15454.6 CRK13652.1 - 2.2e-20 73.0 0.0 1.5e-10 41.5 0.0 2.6 2 0 0 2 2 2 2 Late endosomal/lysosomal adaptor and MAPK and MTOR activator SVIP PF15811.5 CRK13652.1 - 0.0067 16.9 6.9 1.4 9.4 0.1 3.6 3 0 0 3 3 3 2 Small VCP/p97-interacting protein ATP-synt_E PF05680.12 CRK13652.1 - 0.0085 16.4 0.1 7.3 7.0 0.0 2.4 2 0 0 2 2 2 2 ATP synthase E chain PRKG1_interact PF15898.5 CRK13652.1 - 0.027 15.4 0.1 16 6.5 0.0 2.4 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain zf-C4H2 PF10146.9 CRK13652.1 - 0.18 12.1 0.1 2.7 8.2 0.1 2.2 2 0 0 2 2 2 0 Zinc finger-containing protein OrsD PF12013.8 CRK13654.1 - 0.0081 16.6 2.6 0.0086 16.5 0.5 2.2 2 0 0 2 2 2 1 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_2 PF12756.7 CRK13654.1 - 0.08 13.3 0.2 0.19 12.1 0.2 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) FAM76 PF16046.5 CRK13654.1 - 0.49 9.7 14.8 0.053 12.9 6.6 2.2 2 0 0 2 2 2 0 FAM76 protein DUF1677 PF07911.13 CRK13654.1 - 0.79 10.1 10.2 0.18 12.2 0.7 3.5 3 2 1 4 4 4 0 Protein of unknown function (DUF1677) Med7 PF05983.11 CRK13655.1 - 7.1e-58 195.9 0.0 8.6e-58 195.6 0.0 1.1 1 0 0 1 1 1 1 MED7 protein SPOC PF07744.13 CRK13656.1 - 2.7e-27 95.5 0.0 5.3e-27 94.6 0.0 1.5 1 0 0 1 1 1 1 SPOC domain TFIIS_M PF07500.14 CRK13656.1 - 1e-14 55.0 0.5 2.5e-14 53.7 0.1 1.8 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.29 CRK13656.1 - 1.1e-08 34.9 10.3 2.1e-08 33.9 10.3 1.5 1 0 0 1 1 1 1 PHD-finger zf-CW PF07496.15 CRK13656.1 - 0.16 12.0 3.5 0.38 10.8 3.5 1.6 1 0 0 1 1 1 0 CW-type Zinc Finger PHD_2 PF13831.6 CRK13656.1 - 0.22 11.1 5.9 0.41 10.2 5.9 1.4 1 0 0 1 1 1 0 PHD-finger Proteasome PF00227.26 CRK13657.1 - 8.9e-61 204.7 0.1 1.1e-60 204.4 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CRK13657.1 - 2.7e-13 49.3 0.1 8.7e-13 47.7 0.1 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF5624 PF18538.1 CRK13657.1 - 0.014 15.5 0.6 0.033 14.3 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5624) Nitrate_red_gam PF02665.14 CRK13657.1 - 0.062 12.8 0.0 0.087 12.3 0.0 1.1 1 0 0 1 1 1 0 Nitrate reductase gamma subunit PAP2 PF01569.21 CRK13658.1 - 3.1e-26 91.8 1.0 3.1e-26 91.8 1.0 2.1 2 0 0 2 2 2 1 PAP2 superfamily HisKA_7TM PF16927.5 CRK13658.1 - 0.028 14.5 9.7 0.033 14.2 4.4 2.5 2 1 1 3 3 3 0 N-terminal 7TM region of histidine kinase K_oxygenase PF13434.6 CRK13660.1 - 6.9e-108 360.8 0.0 4.3e-107 358.2 0.0 2.1 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) IF-2B PF01008.17 CRK13660.1 - 2.2e-17 63.2 0.0 3.2e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family Pyr_redox_2 PF07992.14 CRK13660.1 - 7.3e-08 32.0 0.0 7.4e-07 28.7 0.0 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NUDIX PF00293.28 CRK13660.1 - 8.1e-08 32.4 0.0 2e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain Pyr_redox_3 PF13738.6 CRK13660.1 - 3.9e-06 26.3 0.1 2.6e-05 23.6 0.0 2.0 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DUF4147 PF13660.6 CRK13660.1 - 0.066 12.7 0.0 4.6 6.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4147) AMP-binding PF00501.28 CRK13661.1 - 1.4e-221 735.5 0.0 2.4e-75 253.8 0.0 3.2 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 CRK13661.1 - 6e-147 490.0 0.0 3e-32 111.9 0.1 7.9 6 2 1 7 7 7 7 Condensation domain PP-binding PF00550.25 CRK13661.1 - 4.2e-49 164.8 13.4 1.5e-08 34.8 0.0 6.9 6 0 0 6 6 6 6 Phosphopantetheine attachment site AMP-binding_C PF13193.6 CRK13661.1 - 1e-13 52.0 0.0 7.9e-06 26.8 0.0 4.4 4 0 0 4 4 4 3 AMP-binding enzyme C-terminal domain WES_acyltransf PF03007.16 CRK13661.1 - 2.9e-05 24.0 0.0 11 5.7 0.0 5.1 5 0 0 5 5 5 3 Wax ester synthase-like Acyl-CoA acyltransferase domain Tim17 PF02466.19 CRK13663.1 - 1.6e-31 109.0 7.3 2.1e-31 108.6 7.3 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Peptidase_M20 PF01546.28 CRK13664.1 - 2.7e-22 79.5 0.0 6.3e-22 78.3 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.32 CRK13664.1 - 8.3e-08 32.8 4.5 0.05 14.5 0.0 6.1 6 0 0 6 6 6 2 WD domain, G-beta repeat M20_dimer PF07687.14 CRK13664.1 - 0.0014 18.5 0.0 0.0027 17.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain ANAPC4_WD40 PF12894.7 CRK13664.1 - 0.0028 17.9 0.2 8.1 6.8 0.0 3.6 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CRK13664.1 - 0.044 12.7 0.2 0.1 11.5 0.0 1.6 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Sugar_tr PF00083.24 CRK13665.1 - 2.6e-64 217.8 21.0 4.2e-43 147.8 9.1 2.2 1 1 1 2 2 2 2 Sugar (and other) transporter Aldedh PF00171.22 CRK13665.1 - 3.4e-60 203.9 3.6 2.5e-55 187.8 0.9 2.3 1 1 1 2 2 2 2 Aldehyde dehydrogenase family adh_short PF00106.25 CRK13665.1 - 9.7e-47 159.0 0.1 1.7e-46 158.2 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK13665.1 - 3.4e-45 154.4 0.0 7.2e-45 153.4 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase MFS_1 PF07690.16 CRK13665.1 - 3.9e-12 45.8 47.7 3.3e-08 32.8 8.7 2.9 2 1 2 4 4 4 3 Major Facilitator Superfamily zf-C2H2_4 PF13894.6 CRK13665.1 - 1e-07 32.1 9.5 0.0039 17.9 0.6 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 CRK13665.1 - 1.1e-07 31.9 14.4 0.0016 18.8 2.3 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type Fungal_trans PF04082.18 CRK13665.1 - 1e-06 28.0 0.1 1.7e-06 27.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain KR PF08659.10 CRK13665.1 - 2.5e-06 27.5 0.0 5.8e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 KR domain zf-C2H2_jaz PF12171.8 CRK13665.1 - 3.4e-05 24.0 1.0 0.013 15.8 0.1 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding Zn_clus PF00172.18 CRK13665.1 - 8e-05 22.7 9.3 8e-05 22.7 9.3 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-met PF12874.7 CRK13665.1 - 0.0003 21.1 4.1 0.072 13.5 0.2 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 CRK13665.1 - 0.02 14.8 0.3 0.02 14.8 0.3 2.5 3 0 0 3 3 2 0 zinc-finger of a C2HC-type Epimerase PF01370.21 CRK13665.1 - 0.026 14.0 0.1 0.056 12.9 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF2070 PF09843.9 CRK13665.1 - 0.46 8.7 5.3 0.73 8.1 5.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) zf-H2C2_2 PF13465.6 CRK13665.1 - 1 9.9 15.3 0.094 13.2 3.0 3.4 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_11 PF16622.5 CRK13665.1 - 1.6 8.6 10.1 5.4 6.9 2.0 2.9 2 0 0 2 2 2 0 zinc-finger C2H2-type ABC2_membrane_2 PF12679.7 CRK13665.1 - 2.7 7.2 7.7 5 6.3 7.7 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein zf-BED PF02892.15 CRK13665.1 - 3 7.9 7.9 1.9 8.6 1.0 2.7 1 1 1 2 2 2 0 BED zinc finger Iso_dh PF00180.20 CRK13666.1 - 2.4e-107 359.1 0.0 2.7e-107 358.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF747 PF05346.11 CRK13667.1 - 1.7e-114 382.6 5.2 2.4e-114 382.1 5.2 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family TrbL PF04610.14 CRK13667.1 - 0.0032 17.2 1.2 0.0061 16.3 1.2 1.4 1 0 0 1 1 1 1 TrbL/VirB6 plasmid conjugal transfer protein GMC_oxred_N PF00732.19 CRK13669.1 - 1.9e-56 191.6 0.0 2.6e-56 191.2 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CRK13669.1 - 6.1e-32 111.1 0.2 1.2e-31 110.2 0.2 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 CRK13669.1 - 0.0026 16.9 0.5 0.24 10.4 0.2 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 CRK13669.1 - 0.016 15.5 0.2 0.039 14.2 0.2 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 CRK13669.1 - 0.03 13.4 0.1 0.059 12.4 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein DAO PF01266.24 CRK13669.1 - 0.037 13.6 1.1 1.3 8.6 0.2 2.6 3 0 0 3 3 3 0 FAD dependent oxidoreductase WD40 PF00400.32 CRK13671.1 - 1.7e-40 136.3 19.1 1.1e-05 26.1 0.7 7.8 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box PF00646.33 CRK13671.1 - 1.7e-10 40.5 0.2 6e-10 38.8 0.1 2.0 2 1 0 2 2 2 1 F-box domain F-box-like PF12937.7 CRK13671.1 - 3e-10 39.8 0.1 6.4e-10 38.8 0.1 1.6 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 CRK13671.1 - 4.6e-08 33.3 0.6 0.66 10.3 0.0 5.3 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 CRK13671.1 - 0.0052 16.4 1.3 1.8 8.1 0.0 2.9 2 1 0 2 2 2 2 PQQ-like domain F-box_4 PF15966.5 CRK13671.1 - 0.016 15.1 0.0 0.052 13.4 0.0 1.9 1 0 0 1 1 1 0 F-box Nup160 PF11715.8 CRK13671.1 - 0.063 11.9 3.5 17 3.9 0.1 4.4 2 1 2 5 5 5 0 Nucleoporin Nup120/160 bZIP_1 PF00170.21 CRK13672.1 - 3.9e-06 26.9 5.2 7.1e-06 26.0 5.2 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 CRK13672.1 - 0.019 15.5 6.5 0.053 14.1 6.5 1.7 1 0 0 1 1 1 0 bZIP Maf transcription factor His_binding PF02098.16 CRK13672.1 - 0.12 12.4 1.2 0.23 11.5 1.2 1.3 1 0 0 1 1 1 0 Tick histamine binding protein bZIP_2 PF07716.15 CRK13672.1 - 1.2 9.3 8.2 2.7 8.2 8.2 1.6 1 0 0 1 1 1 0 Basic region leucine zipper Complex1_LYR PF05347.15 CRK13673.1 - 7.1e-14 51.6 0.0 1.5e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 CRK13673.1 - 0.0097 16.6 0.1 0.022 15.5 0.1 1.7 1 0 0 1 1 1 1 Complex1_LYR-like OmdA PF13376.6 CRK13673.1 - 1.3 9.1 5.6 0.97 9.5 0.1 3.2 3 0 0 3 3 3 0 Bacteriocin-protection, YdeI or OmpD-Associated Fasciclin PF02469.22 CRK13674.1 - 3.3e-30 104.9 0.1 3.1e-16 59.8 0.1 2.4 2 0 0 2 2 2 2 Fasciclin domain Zn_clus PF00172.18 CRK13674.1 - 0.00037 20.6 10.0 0.00037 20.6 10.0 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Orthopox_A5L PF06193.11 CRK13674.1 - 0.13 11.7 0.3 0.28 10.6 0.3 1.5 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like adh_short PF00106.25 CRK13676.1 - 1.5e-38 132.2 0.2 2.5e-38 131.5 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK13676.1 - 2e-34 119.1 1.1 3.6e-34 118.3 1.1 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK13676.1 - 9.5e-10 38.7 1.2 7.8e-09 35.7 1.2 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 CRK13676.1 - 0.061 12.8 1.2 0.13 11.7 0.0 2.0 3 0 0 3 3 3 0 NAD dependent epimerase/dehydratase family p450 PF00067.22 CRK13677.1 - 2e-38 132.3 0.0 2.7e-38 131.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Tmpp129 PF10272.9 CRK13678.1 - 0.21 10.9 0.2 0.46 9.7 0.2 1.5 1 0 0 1 1 1 0 Putative transmembrane protein precursor Fungal_trans_2 PF11951.8 CRK13679.1 - 4e-27 95.0 10.0 6.9e-18 64.6 2.5 4.9 2 2 1 4 4 4 4 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK13679.1 - 9.7e-13 48.0 26.6 3.9e-06 26.9 9.3 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_127 PF07944.12 CRK13679.1 - 0.084 11.4 0.0 5.3 5.4 0.0 2.1 2 0 0 2 2 2 0 Beta-L-arabinofuranosidase, GH127 EAV_GS PF01309.18 CRK13679.1 - 0.26 10.9 3.4 0.81 9.3 0.4 2.7 2 0 0 2 2 2 0 Equine arteritis virus small envelope glycoprotein PSI_integrin PF17205.3 CRK13679.1 - 2.8 7.7 12.0 10 6.0 2.3 2.8 2 0 0 2 2 2 0 Integrin plexin domain MFS_1 PF07690.16 CRK13680.1 - 4.4e-40 137.7 58.3 7.2e-39 133.7 58.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Pec_lyase_C PF00544.19 CRK13681.1 - 6.3e-43 146.8 6.8 8.7e-43 146.4 6.8 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 CRK13681.1 - 0.0019 18.1 11.2 0.0033 17.3 11.2 1.4 1 0 0 1 1 1 1 Right handed beta helix region Ribosomal_60s PF00428.19 CRK13681.1 - 0.0091 16.6 2.8 0.0091 16.6 2.8 2.9 2 1 1 3 3 3 1 60s Acidic ribosomal protein His_Phos_2 PF00328.22 CRK13682.1 - 3.8e-29 102.2 0.0 4.7e-29 101.9 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Sortilin-Vps10 PF15902.5 CRK13683.1 - 2.6e-18 66.0 2.8 1.3e-05 24.2 0.0 5.7 6 0 0 6 6 6 4 Sortilin, neurotensin receptor 3, BNR PF02012.20 CRK13683.1 - 1e-08 33.9 36.9 0.61 10.3 0.6 9.7 9 0 0 9 9 9 7 BNR/Asp-box repeat BNR_2 PF13088.6 CRK13683.1 - 2.4e-06 27.1 14.6 0.4 9.9 0.1 6.4 2 2 4 6 6 6 6 BNR repeat-like domain BNR_6 PF15899.5 CRK13683.1 - 0.00011 21.9 5.3 28 5.1 0.0 6.8 7 0 0 7 7 7 1 BNR-Asp box repeat Glyco_hydro_2_C PF02836.17 CRK13684.1 - 2.1e-102 342.3 0.1 2.9e-102 341.9 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 CRK13684.1 - 3.7e-62 210.1 0.0 8e-62 209.0 0.0 1.6 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 CRK13684.1 - 3.5e-40 137.7 0.1 6.8e-40 136.7 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain DUF4981 PF16353.5 CRK13684.1 - 1.8e-22 79.6 0.0 1e-21 77.2 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function(DUF4981) Glyco_hydro_2 PF00703.21 CRK13684.1 - 1.7e-10 41.5 0.0 1.1e-09 39.0 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Sugar_tr PF00083.24 CRK13685.1 - 2.6e-76 257.3 25.0 3e-76 257.1 25.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK13685.1 - 1.1e-13 50.9 26.9 1.1e-13 50.9 26.9 2.1 1 1 2 3 3 3 1 Major Facilitator Superfamily ELFV_dehydrog PF00208.21 CRK13686.1 - 1.5e-79 267.1 2.0 1.8e-79 266.9 2.0 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_7 PF13241.6 CRK13686.1 - 0.024 15.1 0.1 0.06 13.8 0.1 1.7 2 0 0 2 2 2 0 Putative NAD(P)-binding Homeodomain PF00046.29 CRK13688.1 - 0.00011 22.0 0.6 0.00012 21.8 0.6 1.2 1 0 0 1 1 1 1 Homeodomain DUF2264 PF10022.9 CRK13692.1 - 1.5e-14 53.9 0.0 1.7e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) PAS_4 PF08448.10 CRK13695.1 - 1.6e-06 28.3 0.0 3.5e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 PAS fold Pkinase PF00069.25 CRK13741.1 - 8e-32 110.6 0.0 1.4e-31 109.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK13741.1 - 8.1e-10 38.4 0.0 1.4e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CRK13741.1 - 0.037 12.8 0.1 0.14 10.9 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 CRK13741.1 - 0.063 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-RING_2 PF13639.6 CRK13743.1 - 1.3e-08 35.0 9.1 2.5e-08 34.1 9.1 1.5 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 CRK13743.1 - 1.3e-05 25.3 9.1 3.6e-05 23.9 9.1 1.7 1 1 0 1 1 1 1 FANCL C-terminal domain zf-ANAPC11 PF12861.7 CRK13743.1 - 8.5e-05 22.5 2.3 0.0002 21.3 2.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 CRK13743.1 - 0.00017 21.8 8.0 0.0004 20.6 8.0 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CRK13743.1 - 0.002 18.0 10.9 0.0037 17.1 10.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 CRK13743.1 - 0.0034 17.5 8.1 0.007 16.5 8.1 1.6 1 0 0 1 1 1 1 RING-variant domain C1_1 PF00130.22 CRK13743.1 - 0.0038 17.1 3.5 0.0038 17.1 3.5 1.8 1 1 1 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn_ribbon_17 PF17120.5 CRK13743.1 - 0.025 14.2 5.6 0.06 13.0 5.6 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 CRK13743.1 - 0.04 13.8 5.9 0.081 12.8 5.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CRK13743.1 - 0.068 13.0 9.2 0.13 12.1 9.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 CRK13743.1 - 0.17 12.2 8.3 0.34 11.3 8.3 1.5 1 0 0 1 1 1 0 RING-like domain zf-RING_9 PF13901.6 CRK13743.1 - 0.95 9.4 6.8 2 8.4 6.8 1.4 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon Prok-RING_4 PF14447.6 CRK13743.1 - 1 9.3 6.8 3 7.8 6.9 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 CRK13743.1 - 1.4 9.0 6.3 3.4 7.8 6.3 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Zf_RING PF16744.5 CRK13743.1 - 1.9 8.6 6.1 7.7 6.7 3.9 2.5 2 0 0 2 2 2 0 KIAA1045 RING finger PHD PF00628.29 CRK13743.1 - 2.9 7.8 7.8 5.8 6.9 7.8 1.5 1 0 0 1 1 1 0 PHD-finger Hormone_3 PF00159.18 CRK13745.1 - 0.0056 16.7 49.5 5.5 7.1 0.0 14.7 16 0 0 16 16 16 5 Pancreatic hormone peptide DUF3439 PF11921.8 CRK13745.1 - 0.18 11.8 0.1 0.46 10.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) VHP PF02209.19 CRK13747.1 - 0.12 12.4 1.3 0.15 12.1 1.3 1.2 1 0 0 1 1 1 0 Villin headpiece domain Ribosomal_L1 PF00687.21 CRK13751.1 - 1.8e-62 210.7 1.5 3e-62 210.0 1.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Palm_thioest PF02089.15 CRK13752.1 - 6.7e-78 261.9 0.0 7.9e-78 261.6 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Lipase_2 PF01674.18 CRK13752.1 - 0.003 17.1 0.0 0.0053 16.3 0.0 1.5 1 1 0 1 1 1 1 Lipase (class 2) DUF915 PF06028.11 CRK13752.1 - 0.085 12.2 0.0 0.21 10.9 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Cyclin_N PF00134.23 CRK13754.1 - 2.1e-08 34.0 0.3 4.7e-08 32.8 0.3 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Glyco_transf_28 PF03033.20 CRK13756.1 - 1.8e-23 83.1 0.0 3.8e-23 82.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 CRK13756.1 - 8e-06 24.9 0.0 1.3e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CRK13756.1 - 0.023 14.7 0.0 0.043 13.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain FMN_dh PF01070.18 CRK13759.1 - 2e-83 280.3 0.1 1.5e-48 165.7 0.0 2.0 1 1 1 2 2 2 2 FMN-dependent dehydrogenase IMPDH PF00478.25 CRK13759.1 - 0.00053 19.1 0.2 0.0022 17.0 0.2 1.8 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 CRK13759.1 - 0.00071 19.1 0.1 0.0037 16.7 0.1 1.9 1 1 1 2 2 2 1 Nitronate monooxygenase DHO_dh PF01180.21 CRK13759.1 - 0.0021 17.3 0.2 1.5 7.9 0.0 2.8 3 0 0 3 3 3 2 Dihydroorotate dehydrogenase ThiG PF05690.14 CRK13759.1 - 0.0061 15.9 0.0 0.94 8.7 0.0 2.2 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.17 CRK13759.1 - 0.01 15.0 0.1 0.054 12.6 0.0 1.8 1 1 1 2 2 2 1 Conserved region in glutamate synthase G3P_antiterm PF04309.12 CRK13759.1 - 0.043 13.2 0.0 0.097 12.1 0.0 1.5 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator Peptidase_M19 PF01244.21 CRK13759.1 - 0.046 12.9 0.0 0.17 11.0 0.0 1.9 2 1 0 2 2 2 0 Membrane dipeptidase (Peptidase family M19) IGPS PF00218.21 CRK13759.1 - 0.13 11.5 0.0 0.59 9.3 0.0 2.0 1 1 1 2 2 2 0 Indole-3-glycerol phosphate synthase Ribonucleas_3_3 PF14622.6 CRK13763.1 - 0.00021 21.4 0.0 0.05 13.8 0.1 2.2 2 0 0 2 2 2 2 Ribonuclease-III-like dsrm PF00035.26 CRK13763.1 - 0.00069 20.3 0.0 0.0015 19.2 0.0 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.26 CRK13763.1 - 0.037 14.7 0.0 0.22 12.2 0.0 2.1 1 1 0 1 1 1 0 Ribonuclease III domain PLA2_B PF01735.18 CRK13765.1 - 1.2e-28 99.8 0.0 1.9e-28 99.1 0.0 1.3 1 0 0 1 1 1 1 Lysophospholipase catalytic domain FMO-like PF00743.19 CRK13766.1 - 4.9e-57 193.6 0.0 6.5e-57 193.1 0.0 1.1 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 CRK13766.1 - 2.5e-19 69.7 0.0 6.4e-16 58.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CRK13766.1 - 5.8e-15 55.3 0.0 4.3e-13 49.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CRK13766.1 - 6.1e-08 33.1 0.1 0.016 15.8 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CRK13766.1 - 1.4e-06 28.4 0.1 3.5e-06 27.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CRK13766.1 - 4.7e-06 26.4 0.0 0.0051 16.4 0.1 3.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 CRK13766.1 - 1.9e-05 24.0 0.0 0.00035 19.8 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) IlvN PF07991.12 CRK13766.1 - 1.9e-05 24.3 0.0 0.28 10.7 0.0 2.6 3 0 0 3 3 3 2 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_9 PF13454.6 CRK13766.1 - 0.0016 18.5 0.2 0.13 12.2 0.0 3.1 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 CRK13766.1 - 0.0017 18.7 0.0 3.1 8.3 0.1 2.9 2 1 0 2 2 2 2 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 CRK13766.1 - 0.0027 17.0 0.0 0.0058 15.9 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 CRK13766.1 - 0.003 16.9 0.1 0.0056 16.0 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain 2-Hacid_dh_C PF02826.19 CRK13766.1 - 0.0047 16.3 0.0 0.4 10.0 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.14 CRK13766.1 - 0.017 13.8 0.1 0.03 13.0 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Amino_oxidase PF01593.24 CRK13766.1 - 0.053 12.8 0.0 0.089 12.1 0.0 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Thi4 PF01946.17 CRK13766.1 - 0.062 12.5 0.1 0.31 10.2 0.1 2.1 2 0 0 2 2 2 0 Thi4 family Shikimate_DH PF01488.20 CRK13766.1 - 0.079 13.0 0.0 20 5.3 0.0 2.7 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Septin PF00735.18 CRK13768.1 - 9.7e-118 392.5 0.1 9.7e-118 392.5 0.1 1.7 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 CRK13768.1 - 4.2e-08 33.3 0.9 9.1e-08 32.2 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CRK13768.1 - 8e-05 22.3 0.8 0.0012 18.4 0.0 2.7 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CRK13768.1 - 9.7e-05 22.3 2.5 0.0036 17.2 0.8 3.2 2 1 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 CRK13768.1 - 0.00016 22.2 0.8 0.036 14.6 0.0 2.5 2 0 0 2 2 2 1 ABC transporter AAA_22 PF13401.6 CRK13768.1 - 0.0005 20.3 0.0 0.049 13.9 0.0 3.1 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.6 CRK13768.1 - 0.0022 18.4 0.1 0.0077 16.6 0.0 2.0 2 0 0 2 2 1 1 AAA ATPase domain Roc PF08477.13 CRK13768.1 - 0.0029 17.8 0.0 0.0067 16.6 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 CRK13768.1 - 0.004 16.5 1.9 0.0061 15.9 0.0 2.1 2 0 0 2 2 2 1 AIG1 family Ras PF00071.22 CRK13768.1 - 0.015 14.9 0.1 0.06 12.9 0.0 2.1 2 0 0 2 2 2 0 Ras family AAA_29 PF13555.6 CRK13768.1 - 0.018 14.8 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 CRK13768.1 - 0.074 12.4 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_24 PF13479.6 CRK13768.1 - 0.089 12.5 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CRK13768.1 - 0.11 12.9 0.7 0.8 10.1 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_7 PF12775.7 CRK13768.1 - 0.12 11.8 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Dynamin_N PF00350.23 CRK13768.1 - 0.57 10.2 9.6 1.2 9.2 0.0 3.4 3 1 0 3 3 2 0 Dynamin family Exonuc_VII_L PF02601.15 CRK13768.1 - 0.75 9.3 7.8 1.2 8.6 7.8 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit AP1AR PF15745.5 CRK13768.1 - 0.82 9.3 9.2 1.7 8.2 9.2 1.4 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein TSNAXIP1_N PF15739.5 CRK13768.1 - 1.2 9.6 14.1 8.8 6.8 0.0 2.7 2 1 1 3 3 3 0 Translin-associated factor X-interacting N-terminus Caldesmon PF02029.15 CRK13768.1 - 1.3 7.7 19.4 2 7.1 19.4 1.2 1 0 0 1 1 1 0 Caldesmon Atg14 PF10186.9 CRK13768.1 - 4.8 6.2 7.8 7.4 5.5 7.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 S4 PF01479.25 CRK13770.1 - 2.9e-12 46.1 0.0 1.3e-11 44.0 0.0 2.2 2 0 0 2 2 2 1 S4 domain XRN_M PF17846.1 CRK13770.1 - 0.029 13.3 0.2 0.87 8.5 0.1 2.1 1 1 1 2 2 2 0 Xrn1 helical domain MutS_III PF05192.18 CRK13770.1 - 3.8 7.7 7.3 10 6.3 0.7 2.3 1 1 1 2 2 2 0 MutS domain III RBM39linker PF15519.6 CRK13770.1 - 4.9 8.3 9.1 6.7 7.9 1.6 2.6 2 0 0 2 2 2 0 linker between RRM2 and RRM3 domains in RBM39 protein La PF05383.17 CRK13772.1 - 5.9e-13 48.7 0.0 1.1e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 CRK13772.1 - 1e-06 28.4 0.2 1.8e-06 27.7 0.2 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MFS_1 PF07690.16 CRK13774.1 - 2.1e-40 138.7 29.8 3.3e-40 138.1 29.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK13774.1 - 2.2e-10 40.0 1.7 2.2e-10 40.0 1.7 1.6 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 CRK13774.1 - 0.00011 20.9 2.5 0.00016 20.3 2.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Nucleoporin_N PF08801.11 CRK13780.1 - 3.5e-110 368.7 0.0 1.1e-97 327.6 0.0 2.3 2 0 0 2 2 2 2 Nup133 N terminal like Nucleoporin_C PF03177.14 CRK13780.1 - 1.3e-77 261.9 13.3 1.5e-48 166.0 0.3 4.7 2 1 3 5 5 5 3 Non-repetitive/WGA-negative nucleoporin C-terminal adh_short PF00106.25 CRK13780.1 - 6.3e-51 172.6 0.4 2.5e-36 125.0 0.1 2.5 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CRK13780.1 - 3.1e-27 95.6 0.7 1.4e-21 77.2 0.0 3.2 3 0 0 3 3 3 2 Enoyl-(Acyl carrier protein) reductase GalP_UDP_tr_C PF02744.17 CRK13780.1 - 2.1e-22 79.6 0.0 5e-22 78.4 0.0 1.5 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain KR PF08659.10 CRK13780.1 - 1.3e-09 38.2 0.1 0.001 19.0 0.0 2.7 2 0 0 2 2 2 2 KR domain Phasin_2 PF09361.10 CRK13780.1 - 1.8e-05 24.9 2.6 0.18 12.1 0.3 2.9 2 0 0 2 2 2 2 Phasin protein NAD_binding_10 PF13460.6 CRK13780.1 - 3.2e-05 23.9 0.1 0.27 11.1 0.0 2.6 2 0 0 2 2 2 2 NAD(P)H-binding NAD_binding_2 PF03446.15 CRK13780.1 - 0.00026 21.2 0.0 1.7 8.8 0.0 3.0 2 0 0 2 2 2 2 NAD binding domain of 6-phosphogluconate dehydrogenase Glyco_tran_WecB PF03808.13 CRK13780.1 - 0.0004 20.4 0.0 2.7 7.9 0.0 3.6 3 0 0 3 3 3 2 Glycosyl transferase WecB/TagA/CpsF family 3HCDH_N PF02737.18 CRK13780.1 - 0.00059 19.8 4.3 0.49 10.3 0.1 3.0 3 0 0 3 3 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 CRK13780.1 - 0.00096 18.6 0.2 0.36 10.2 0.1 2.7 3 0 0 3 3 3 1 GDP-mannose 4,6 dehydratase SbcD_C PF12320.8 CRK13780.1 - 0.0046 17.2 3.9 2.2 8.6 0.3 3.1 2 0 0 2 2 2 2 Type 5 capsule protein repressor C-terminal domain ADSL_C PF10397.9 CRK13780.1 - 0.0057 17.2 2.3 7.7 7.1 0.1 4.2 5 0 0 5 5 3 1 Adenylosuccinate lyase C-terminus MgtE PF01769.16 CRK13780.1 - 0.011 16.1 0.9 0.036 14.4 0.9 1.9 1 0 0 1 1 1 0 Divalent cation transporter ApbA PF02558.16 CRK13780.1 - 0.032 13.9 0.1 12 5.5 0.0 3.2 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA VWA_3 PF13768.6 CRK13780.1 - 0.045 13.7 2.9 3.7 7.5 0.2 2.8 2 0 0 2 2 2 0 von Willebrand factor type A domain FCH PF00611.23 CRK13780.1 - 0.098 13.0 0.1 39 4.6 0.0 3.2 2 0 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain DUF3479 PF11965.8 CRK13780.1 - 0.19 11.8 1.7 24 5.0 0.1 3.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3479) DUF3995 PF13160.6 CRK13780.1 - 7.9 6.9 8.0 1.6 9.1 0.4 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3995) Erg28 PF03694.13 CRK13782.1 - 6.7e-45 152.0 2.3 9.9e-45 151.4 2.3 1.3 1 0 0 1 1 1 1 Erg28 like protein GalP_UDP_transf PF01087.22 CRK13784.1 - 1.4e-68 230.9 0.3 8e-68 228.5 0.1 1.9 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 CRK13784.1 - 2.5e-61 206.2 0.3 8.9e-61 204.5 0.1 1.8 1 1 1 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.23 CRK13784.1 - 4.9e-06 27.2 0.0 8.1e-05 23.3 0.0 2.4 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.8 CRK13784.1 - 0.0064 17.0 0.0 0.014 15.9 0.0 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DUF4921 PF16268.5 CRK13784.1 - 0.023 13.6 0.7 1 8.1 0.0 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4921) ZZ PF00569.17 CRK13785.1 - 3.3e-12 46.0 5.2 5.6e-12 45.3 5.2 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.31 CRK13785.1 - 1.8e-08 34.4 0.0 3.3e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CRK13785.1 - 1.7e-05 25.0 0.0 2.6e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain SWIRM PF04433.17 CRK13787.1 - 2.1e-08 34.4 0.0 2.7e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 SWIRM domain GalP_UDP_transf PF01087.22 CRK13791.1 - 2.5e-67 226.8 0.1 4.9e-67 225.9 0.1 1.4 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain DUF2781 PF10914.8 CRK13791.1 - 1.8e-33 116.0 7.7 1.8e-33 116.0 7.7 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2781) Nucleoporin_N PF08801.11 CRK13791.1 - 2.2e-24 86.0 0.5 7.2e-24 84.3 0.4 1.7 1 1 1 2 2 2 1 Nup133 N terminal like adh_short PF00106.25 CRK13791.1 - 5.4e-24 84.7 0.1 1.1e-23 83.7 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase GalP_UDP_tr_C PF02744.17 CRK13791.1 - 1.2e-19 70.7 0.3 2.9e-19 69.4 0.3 1.6 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain adh_short_C2 PF13561.6 CRK13791.1 - 9.6e-16 58.0 0.0 1.7e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase PBP PF01161.20 CRK13791.1 - 7.4e-11 42.5 0.0 1.7e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein HIT PF01230.23 CRK13791.1 - 0.0037 18.0 0.1 0.021 15.5 0.0 2.3 2 0 0 2 2 2 1 HIT domain ZZ PF00569.17 CRK13794.1 - 5.6e-12 45.3 5.5 9.6e-12 44.5 5.5 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.31 CRK13794.1 - 3.6e-08 33.5 0.0 1.2e-07 31.8 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain SWIRM PF04433.17 CRK13794.1 - 3.8e-07 30.3 0.0 1.3e-06 28.7 0.0 1.8 1 0 0 1 1 1 1 SWIRM domain DUF2781 PF10914.8 CRK13797.1 - 1.3e-32 113.2 7.8 2.3e-32 112.4 7.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) PBP PF01161.20 CRK13797.1 - 1.6e-11 44.6 0.0 2.6e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Methyltransf_23 PF13489.6 CRK13799.1 - 6.2e-19 68.4 0.0 9.6e-19 67.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK13799.1 - 3.8e-13 49.9 0.0 1.1e-12 48.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CRK13799.1 - 7.6e-13 48.9 0.0 2.4e-12 47.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK13799.1 - 4.4e-08 33.8 0.0 4.2e-07 30.6 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK13799.1 - 5.9e-08 32.6 0.0 1.4e-06 28.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CRK13799.1 - 3.9e-06 26.4 0.0 3.9e-05 23.1 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 CRK13799.1 - 0.0017 18.0 0.0 0.0028 17.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.9 CRK13799.1 - 0.0032 17.2 0.0 0.0051 16.6 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_4 PF02390.17 CRK13799.1 - 0.0057 16.1 0.0 0.043 13.3 0.0 2.3 3 0 0 3 3 3 1 Putative methyltransferase PrmA PF06325.13 CRK13799.1 - 0.0076 15.7 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 CRK13799.1 - 0.14 12.3 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Peptidase_M43 PF05572.13 CRK13801.1 - 2.9e-18 66.2 0.1 7.1e-18 65.0 0.1 1.6 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 CRK13801.1 - 1.8e-05 25.0 0.7 3.2e-05 24.2 0.5 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M10 PF00413.24 CRK13801.1 - 0.00042 20.2 0.0 0.00064 19.6 0.0 1.4 1 0 0 1 1 1 1 Matrixin Reprolysin_3 PF13582.6 CRK13801.1 - 0.00064 20.2 0.1 0.0012 19.3 0.1 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 CRK13801.1 - 0.0051 16.5 0.1 0.0076 15.9 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 CRK13801.1 - 0.022 14.0 0.1 0.04 13.1 0.1 1.4 1 0 0 1 1 1 0 Met-zincin Glyco_hydro_7 PF00840.20 CRK13803.1 - 0.002 16.9 0.0 0.0021 16.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Glyco_hydro_7 PF00840.20 CRK13805.1 - 1.4e-179 597.4 4.4 1.6e-179 597.2 4.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 BTB PF00651.31 CRK13807.1 - 1e-05 25.7 0.0 0.0001 22.5 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain MFS_1 PF07690.16 CRK13808.1 - 7.8e-13 48.1 20.6 7.8e-13 48.1 20.6 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF4293 PF14126.6 CRK13808.1 - 0.007 16.6 15.4 0.091 13.0 0.1 3.3 3 0 0 3 3 3 2 Domain of unknown function (DUF4293) TruB_C PF09142.11 CRK13808.1 - 0.012 15.4 0.6 7.2 6.5 0.1 2.7 2 0 0 2 2 2 0 tRNA Pseudouridine synthase II, C terminal Glycos_trans_3N PF02885.17 CRK13808.1 - 0.051 13.4 0.5 4.4 7.2 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family, helical bundle domain Glyco_hydro_7 PF00840.20 CRK13810.1 - 9.8e-21 74.0 0.0 1.3e-20 73.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 BTB PF00651.31 CRK13812.1 - 1.5e-05 25.2 0.0 8.8e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain MFS_1 PF07690.16 CRK13814.1 - 0.00042 19.3 10.2 0.00042 19.3 10.2 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Rhodanese PF00581.20 CRK13815.1 - 2.2e-11 44.2 0.0 3.4e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain Wzy_C PF04932.15 CRK13815.1 - 0.18 11.4 6.3 0.64 9.6 0.1 3.0 1 1 0 2 2 2 0 O-Antigen ligase HD_3 PF13023.6 CRK13818.1 - 4.3e-46 156.9 0.0 6.7e-46 156.2 0.0 1.3 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 CRK13818.1 - 5.4e-08 32.8 0.0 1.3e-07 31.6 0.0 1.5 1 1 0 1 1 1 1 HD containing hydrolase-like enzyme TPP_enzyme_N PF02776.18 CRK13820.1 - 2.5e-32 111.8 2.3 4.2e-32 111.1 2.3 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 CRK13820.1 - 2.6e-17 62.8 0.0 5.7e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 CRK13820.1 - 1e-12 48.1 0.0 3.3e-12 46.5 0.0 1.9 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain ALG3 PF05208.13 CRK13863.1 - 1.4e-73 248.4 8.3 1.7e-73 248.1 8.3 1.0 1 0 0 1 1 1 1 ALG3 protein DUF2723 PF11028.8 CRK13863.1 - 0.25 11.3 0.1 0.25 11.3 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2723) Helicase_C PF00271.31 CRK13890.1 - 6.6e-05 23.2 0.1 7.8e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF5549 PF17703.1 CRK13890.1 - 0.17 11.5 0.2 0.18 11.4 0.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5549) Pkinase PF00069.25 CRK13892.1 - 8.8e-22 77.7 0.0 9.3e-22 77.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK13892.1 - 1.9e-14 53.6 0.0 2.2e-14 53.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CRK13892.1 - 0.0012 18.2 0.0 0.0012 18.2 0.0 1.0 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CRK13892.1 - 0.014 14.2 0.0 0.014 14.2 0.0 1.0 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 CRK13892.1 - 0.035 13.5 0.0 0.039 13.3 0.0 1.0 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 CRK13892.1 - 0.073 12.7 0.0 0.085 12.5 0.0 1.1 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 CRK13892.1 - 0.074 13.0 0.0 0.074 13.0 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 CRK13892.1 - 0.079 12.0 0.0 0.088 11.9 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 CRK13892.1 - 0.14 11.1 0.0 0.19 10.6 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain MciZ PF13072.6 CRK13907.1 - 0.042 13.7 0.2 0.08 12.8 0.2 1.5 1 0 0 1 1 1 0 Mother cell inhibitor of FtsZ FAM83 PF07894.12 CRK13907.1 - 0.35 10.4 2.6 0.59 9.6 2.6 1.5 1 1 0 1 1 1 0 FAM83 A-H Fungal_trans PF04082.18 CRK13909.1 - 3.4e-13 49.3 0.1 4.5e-12 45.6 0.1 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK13909.1 - 3.2e-08 33.6 14.6 3.2e-08 33.6 14.6 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4381 PF14316.6 CRK13909.1 - 0.047 13.9 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Glyco_hydro_88 PF07470.13 CRK13910.1 - 8.4e-13 48.1 0.4 1.4e-12 47.4 0.4 1.4 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Peptidase_S8 PF00082.22 CRK13911.1 - 3e-39 135.1 0.5 4.7e-39 134.4 0.5 1.2 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 CRK13911.1 - 8.4e-06 26.5 0.0 2e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 Fn3-like domain Cellulase PF00150.18 CRK13912.1 - 8.2e-16 58.3 1.3 1.8e-15 57.1 1.3 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) RXLR PF16810.5 CRK13913.1 - 0.22 11.9 3.7 0.26 11.7 3.7 1.1 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity Herpes_capsid PF06112.11 CRK13913.1 - 1.8 8.6 8.0 1.9 8.5 8.0 1.0 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Aldose_epim PF01263.20 CRK13914.1 - 2.9e-51 174.6 0.4 4.2e-51 174.0 0.4 1.2 1 0 0 1 1 1 1 Aldose 1-epimerase Cellulase PF00150.18 CRK13914.1 - 0.011 15.2 0.0 0.039 13.4 0.0 1.8 2 1 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) Aldose_epim PF01263.20 CRK13916.1 - 2.7e-52 178.0 0.2 3.4e-52 177.6 0.2 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Atx10homo_assoc PF09759.9 CRK13917.1 - 0.01 15.8 0.1 0.34 11.0 0.1 2.8 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain TetR_C_11 PF16859.5 CRK13917.1 - 6.7 7.1 13.5 12 6.2 0.4 4.7 4 0 0 4 4 4 0 Tetracyclin repressor-like, C-terminal domain Ribosomal_L13e PF01294.18 CRK13918.1 - 1.4e-75 253.1 1.6 2.2e-75 252.5 1.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L13e COX14 PF14880.6 CRK13919.1 - 1.4e-19 69.7 0.3 3e-19 68.6 0.3 1.6 1 0 0 1 1 1 1 Cytochrome oxidase c assembly GPHR_N PF12537.8 CRK13919.1 - 0.064 13.3 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 The Golgi pH Regulator (GPHR) Family N-terminal PRP4 PF08799.11 CRK13919.1 - 0.1 12.1 0.6 0.2 11.2 0.6 1.5 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Ribosomal_L13e PF01294.18 CRK13922.1 - 1.4e-75 253.1 1.6 2.2e-75 252.5 1.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L13e DAHP_synth_1 PF00793.20 CRK13923.1 - 2.7e-102 341.3 0.1 4.3e-102 340.7 0.1 1.2 1 0 0 1 1 1 1 DAHP synthetase I family COX14 PF14880.6 CRK13923.1 - 3.8e-18 65.1 0.2 6.9e-18 64.2 0.2 1.5 1 0 0 1 1 1 1 Cytochrome oxidase c assembly AbiEi_1 PF09407.10 CRK13923.1 - 0.083 13.2 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 AbiEi antitoxin C-terminal domain Ribosomal_L50 PF10501.9 CRK13925.1 - 7.1e-16 58.3 0.0 1.5e-15 57.2 0.0 1.6 1 1 0 1 1 1 1 Ribosomal subunit 39S CVNH PF08881.10 CRK13926.1 - 5.2e-24 84.9 0.1 1e-23 83.9 0.1 1.5 1 0 0 1 1 1 1 CVNH domain Ribosomal_L50 PF10501.9 CRK13927.1 - 8.3e-16 58.1 0.0 1.7e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 Ribosomal subunit 39S CVNH PF08881.10 CRK13928.1 - 4.6e-25 88.2 0.1 5.7e-25 88.0 0.1 1.1 1 0 0 1 1 1 1 CVNH domain RSN1_TM PF13967.6 CRK13931.1 - 5.3e-44 149.7 3.5 7.6e-44 149.2 3.5 1.2 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 CRK13931.1 - 1.5e-26 93.7 0.0 2.2e-26 93.2 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RRM_1 PF00076.22 CRK13931.1 - 0.08 12.8 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) F-box-like PF12937.7 CRK13932.1 - 6.3e-05 22.8 0.1 0.00017 21.4 0.1 1.8 1 0 0 1 1 1 1 F-box-like RSN1_7TM PF02714.15 CRK13933.1 - 5.3e-85 285.1 12.5 5.3e-85 285.1 12.5 2.2 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 CRK13933.1 - 3e-43 147.3 3.7 3e-43 147.3 3.7 2.5 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 CRK13933.1 - 9.8e-26 91.0 0.0 1.5e-25 90.4 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 CRK13933.1 - 7.2e-22 77.4 0.2 4.1e-21 75.0 0.1 2.2 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter RRM_1 PF00076.22 CRK13933.1 - 0.2 11.5 0.0 0.4 10.5 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DNA_processg_A PF02481.15 CRK13934.1 - 0.031 13.5 0.0 0.033 13.4 0.0 1.1 1 0 0 1 1 1 0 DNA recombination-mediator protein A Peroxidase_2 PF01328.17 CRK13936.1 - 1.2e-47 162.9 0.0 1.6e-47 162.5 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 DPM3 PF08285.11 CRK13937.1 - 1.2e-35 121.5 0.2 1.3e-35 121.4 0.2 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF4407 PF14362.6 CRK13939.1 - 0.83 9.0 3.1 1.8 7.8 3.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Oxidored-like PF09791.9 CRK13940.1 - 1.7e-24 85.2 1.7 1.7e-24 85.2 1.7 2.3 2 0 0 2 2 2 1 Oxidoreductase-like protein, N-terminal Serglycin PF04360.12 CRK13940.1 - 0.025 14.5 0.0 0.037 14.0 0.0 1.2 1 0 0 1 1 1 0 Serglycin DUF5522 PF17653.1 CRK13940.1 - 0.2 11.7 1.3 0.39 10.7 1.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5522) LysM PF01476.20 CRK13941.1 - 1.1e-13 50.9 1.0 0.0054 16.8 0.0 4.5 4 0 0 4 4 4 4 LysM domain HTH_Tnp_1 PF01527.20 CRK13941.1 - 0.095 13.0 0.0 9.4 6.6 0.0 2.6 3 0 0 3 3 3 0 Transposase Glyco_hydro_18 PF00704.28 CRK13942.1 - 2.2e-36 126.2 0.0 2.4e-36 126.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_18 PF00704.28 CRK13943.1 - 1.6e-09 37.9 1.5 3.1e-09 37.0 1.5 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 GMC_oxred_N PF00732.19 CRK13945.1 - 6.3e-61 206.3 0.0 1.1e-60 205.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CRK13945.1 - 3.6e-31 108.6 0.0 7.2e-31 107.6 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 CRK13945.1 - 0.00034 19.8 2.0 0.00037 19.7 0.8 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 CRK13945.1 - 0.0028 16.8 1.0 0.17 10.9 1.1 2.3 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 CRK13945.1 - 0.0073 15.6 0.2 0.021 14.1 0.2 1.7 1 0 0 1 1 1 1 Thi4 family Pribosyltran PF00156.27 CRK13946.1 - 2.6e-06 27.0 0.0 6.4e-06 25.8 0.0 1.6 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Sugar_tr PF00083.24 CRK13947.1 - 5.8e-101 338.6 28.9 7.2e-101 338.3 28.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK13947.1 - 1.5e-17 63.6 29.1 1.5e-17 63.6 29.1 2.3 1 1 0 2 2 2 1 Major Facilitator Superfamily DUF983 PF06170.12 CRK13947.1 - 0.16 12.4 4.1 0.34 11.4 1.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF983) DHDPS PF00701.22 CRK13948.1 - 7.3e-42 143.1 0.0 8.7e-42 142.8 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family CbiD PF01888.17 CRK13948.1 - 0.019 14.3 0.1 0.032 13.6 0.1 1.3 1 0 0 1 1 1 0 CbiD MoCF_biosynth PF00994.24 CRK13948.1 - 0.026 14.2 0.1 0.059 13.0 0.0 1.6 2 0 0 2 2 2 0 Probable molybdopterin binding domain Fungal_trans_2 PF11951.8 CRK13949.1 - 9.7e-16 57.5 0.3 2e-15 56.5 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK13949.1 - 3.2e-09 36.7 12.0 5e-09 36.1 12.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 CRK13950.1 - 4.1e-36 124.3 1.3 1.8e-17 63.4 0.1 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CRK13950.1 - 7.2e-32 110.8 2.3 2.7e-13 50.0 0.1 3.0 2 1 1 3 3 3 3 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK13950.1 - 0.0011 18.9 0.2 0.0024 17.8 0.1 1.6 2 0 0 2 2 2 1 KR domain 3HCDH_N PF02737.18 CRK13950.1 - 0.0038 17.1 0.0 0.0053 16.7 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 CRK13950.1 - 0.017 14.6 0.1 0.034 13.6 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CRK13950.1 - 0.034 13.5 0.0 0.047 13.1 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 CRK13950.1 - 0.068 12.3 0.0 0.096 11.8 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain ABC_tran PF00005.27 CRK13952.1 - 0.069 13.7 2.7 1.3 9.6 0.0 2.3 2 1 0 2 2 2 0 ABC transporter Actin PF00022.19 CRK13955.1 - 1.8e-27 96.0 0.0 2.5e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 Actin ADH_N PF08240.12 CRK13955.1 - 1e-15 57.5 0.2 2e-07 30.8 0.0 2.4 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CRK13955.1 - 3.3e-06 27.1 1.1 6.5e-06 26.2 1.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ThiF PF00899.21 CRK13955.1 - 0.17 11.2 1.0 0.29 10.4 1.0 1.3 1 0 0 1 1 1 0 ThiF family bZIP_1 PF00170.21 CRK13958.1 - 5.8e-05 23.1 5.4 0.0022 18.1 3.6 2.1 2 0 0 2 2 2 1 bZIP transcription factor Packaging_FI PF14000.6 CRK13958.1 - 0.0002 21.8 0.6 0.00045 20.7 0.3 1.7 2 0 0 2 2 2 1 DNA packaging protein FI TSC22 PF01166.18 CRK13958.1 - 0.018 15.4 0.7 0.43 10.9 0.0 2.2 2 0 0 2 2 2 0 TSC-22/dip/bun family Wtap PF17098.5 CRK13958.1 - 0.047 13.6 1.6 0.069 13.1 1.6 1.2 1 0 0 1 1 1 0 WTAP/Mum2p family ADIP PF11559.8 CRK13958.1 - 0.062 13.4 5.6 0.087 12.9 5.6 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding ABC_tran_CTD PF16326.5 CRK13958.1 - 0.07 13.4 5.6 0.11 12.7 5.6 1.3 1 0 0 1 1 1 0 ABC transporter C-terminal domain DivIC PF04977.15 CRK13958.1 - 0.087 12.6 6.4 0.4 10.5 0.2 2.2 2 0 0 2 2 2 0 Septum formation initiator DUF1192 PF06698.11 CRK13958.1 - 0.16 12.0 5.8 0.18 11.9 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1192) DUF5582 PF17819.1 CRK13958.1 - 0.17 12.4 0.3 0.25 11.8 0.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5582) bZIP_2 PF07716.15 CRK13958.1 - 0.24 11.5 13.5 1.9 8.6 0.5 2.2 2 0 0 2 2 2 0 Basic region leucine zipper SlyX PF04102.12 CRK13958.1 - 0.81 10.3 6.7 2.8 8.6 0.4 2.3 1 1 1 2 2 2 0 SlyX BMFP PF04380.13 CRK13958.1 - 7.2 7.2 8.6 0.26 11.8 2.2 1.8 2 0 0 2 2 2 0 Membrane fusogenic activity zf-C3HC4_3 PF13920.6 CRK13959.1 - 6e-09 35.6 11.2 9e-09 35.1 11.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CRK13959.1 - 1.3e-05 24.9 14.1 2e-05 24.3 14.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CRK13959.1 - 1.6e-05 25.2 13.1 2.3e-05 24.7 13.1 1.3 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 CRK13959.1 - 2e-05 24.4 11.5 3.2e-05 23.7 11.5 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CRK13959.1 - 0.00012 22.0 13.2 0.00019 21.3 13.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 CRK13959.1 - 0.00087 19.3 5.3 0.0013 18.7 5.3 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 CRK13959.1 - 0.00093 19.2 9.4 0.001 19.0 6.0 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CRK13959.1 - 0.0025 17.7 14.0 0.0038 17.1 14.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 CRK13959.1 - 0.0071 16.1 9.2 0.014 15.2 9.2 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Baculo_IE-1 PF05290.11 CRK13959.1 - 0.013 15.5 3.5 0.018 15.0 3.5 1.1 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-P11 PF03854.14 CRK13959.1 - 0.14 11.8 6.8 0.23 11.1 6.8 1.3 1 0 0 1 1 1 0 P-11 zinc finger TBCC PF07986.12 CRK13959.1 - 0.21 11.3 3.3 0.3 10.8 3.3 1.2 1 0 0 1 1 1 0 Tubulin binding cofactor C DZR PF12773.7 CRK13959.1 - 1.7 8.8 8.2 5.5 7.1 8.3 1.8 1 1 1 2 2 2 0 Double zinc ribbon zf-C3HC4_4 PF15227.6 CRK13959.1 - 2.6 8.3 10.6 4.6 7.5 10.6 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF1272 PF06906.11 CRK13959.1 - 9.4 6.4 10.8 15 5.8 1.0 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1272) Nup192 PF11894.8 CRK13960.1 - 1e-111 374.3 0.3 1.2e-111 374.2 0.3 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 JAB PF01398.21 CRK13963.1 - 0.0039 17.2 1.4 0.011 15.7 1.4 1.8 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease His_Phos_2 PF00328.22 CRK13978.1 - 6.4e-33 114.6 0.1 6.9e-33 114.5 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) MCM_OB PF17207.3 CRK13996.1 - 6.3e-35 119.8 0.3 7.1e-35 119.6 0.3 1.0 1 0 0 1 1 1 1 MCM OB domain DUF1236 PF06823.12 CRK13996.1 - 0.016 15.0 0.1 1.2 9.1 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1236) 2-Hacid_dh_C PF02826.19 CRK13998.1 - 2.4e-50 170.4 0.0 4.5e-50 169.5 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CRK13998.1 - 9.4e-16 57.7 0.0 1.4e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Beta_helix PF13229.6 CRK13998.1 - 9.5e-05 22.3 3.8 0.00017 21.4 3.8 1.4 1 0 0 1 1 1 1 Right handed beta helix region NAD_binding_2 PF03446.15 CRK13998.1 - 0.00047 20.4 0.0 0.0011 19.2 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Dynamin_N PF00350.23 CRK14000.1 - 5.5e-27 94.9 1.5 4.5e-12 46.3 0.2 3.3 2 2 0 2 2 2 2 Dynamin family MMR_HSR1 PF01926.23 CRK14000.1 - 2.9e-11 43.4 4.4 0.001 19.2 0.3 4.6 2 2 0 2 2 2 2 50S ribosome-binding GTPase Thioesterase PF00975.20 CRK14000.1 - 4.7e-11 43.2 0.2 2e-10 41.2 0.0 2.3 2 0 0 2 2 1 1 Thioesterase domain ABC_tran PF00005.27 CRK14000.1 - 8.5e-09 36.0 0.4 0.009 16.5 0.0 2.9 2 0 0 2 2 2 2 ABC transporter Abhydrolase_6 PF12697.7 CRK14000.1 - 1e-05 26.3 3.3 2.4e-05 25.1 3.3 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family AAA_29 PF13555.6 CRK14000.1 - 0.00016 21.4 0.1 1 9.1 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SSE PF00437.20 CRK14000.1 - 0.00038 19.6 0.0 0.85 8.6 0.0 2.6 2 0 0 2 2 2 2 Type II/IV secretion system protein CoaE PF01121.20 CRK14000.1 - 0.00046 19.9 1.5 0.92 9.2 0.1 2.6 2 0 0 2 2 2 2 Dephospho-CoA kinase Lsr2 PF11774.8 CRK14000.1 - 0.0029 17.7 5.5 4.1 7.6 0.0 5.4 5 1 1 6 6 5 2 Lsr2 MeaB PF03308.16 CRK14000.1 - 0.0052 15.8 0.1 3.3 6.6 0.0 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 CRK14000.1 - 0.0066 16.0 1.0 1.6 8.3 0.1 2.5 2 0 0 2 2 2 1 AAA domain AIG1 PF04548.16 CRK14000.1 - 0.0089 15.4 0.5 8.2 5.7 0.0 3.5 4 0 0 4 4 4 0 AIG1 family AAA_22 PF13401.6 CRK14000.1 - 0.018 15.3 0.0 13 6.1 0.0 3.0 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 CRK14000.1 - 0.021 14.7 3.1 6 6.7 0.0 3.3 4 0 0 4 4 4 0 RsgA GTPase AAA_18 PF13238.6 CRK14000.1 - 0.023 15.3 0.3 15 6.2 0.0 3.0 3 0 0 3 3 2 0 AAA domain TsaE PF02367.17 CRK14000.1 - 0.04 13.9 0.0 16 5.5 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Glyco_hydro_6 PF01341.17 CRK14000.1 - 0.042 13.6 0.3 12 5.5 0.0 2.6 2 0 0 2 2 2 0 Glycosyl hydrolases family 6 PRK PF00485.18 CRK14000.1 - 0.048 13.4 0.2 14 5.3 0.0 2.8 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_30 PF13604.6 CRK14000.1 - 0.051 13.3 0.0 15 5.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain GCN5L1 PF06320.13 CRK14000.1 - 0.078 13.1 0.6 26 5.0 0.1 3.0 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) POLO_box PF00659.18 CRK14000.1 - 0.11 12.7 0.6 20 5.5 0.1 2.5 2 0 0 2 2 2 0 POLO box duplicated region Abhydrolase_3 PF07859.13 CRK14000.1 - 0.15 11.9 0.0 0.41 10.5 0.0 1.7 1 0 0 1 1 1 0 alpha/beta hydrolase fold CooT PF10133.9 CRK14000.1 - 0.8 10.0 3.0 28 5.1 0.1 3.9 4 0 0 4 4 3 0 CO dehydrogenase accessory protein CooT DnaJ PF00226.31 CRK14002.1 - 3.7e-20 71.8 0.3 3.7e-20 71.8 0.3 2.2 2 0 0 2 2 2 1 DnaJ domain Metallophos PF00149.28 CRK14003.1 - 3.6e-11 43.9 0.0 7.2e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CRK14003.1 - 7.3e-07 29.5 0.0 0.00027 21.2 0.0 2.3 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 CRK14005.1 - 3.4e-11 44.0 0.0 6.5e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CRK14005.1 - 9.8e-07 29.1 0.0 0.00035 20.8 0.0 2.3 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain Pkinase PF00069.25 CRK14007.1 - 1.5e-43 149.1 0.0 1.2e-40 139.6 0.0 3.7 4 0 0 4 4 4 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK14007.1 - 4.7e-29 101.4 0.0 2.7e-25 89.1 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase TPR_12 PF13424.6 CRK14007.1 - 1.7e-06 28.2 5.8 7.4e-05 23.0 1.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TEA PF01285.18 CRK14007.1 - 0.00035 20.6 0.0 1.5 8.9 0.0 2.8 2 0 0 2 2 2 2 TEA/ATTS domain APH PF01636.23 CRK14007.1 - 0.0068 16.4 0.1 0.015 15.2 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family TPR_1 PF00515.28 CRK14007.1 - 0.025 14.4 0.3 0.087 12.7 0.1 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 CRK14007.1 - 0.037 14.1 0.2 0.26 11.5 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 CRK14007.1 - 0.054 14.2 0.5 0.51 11.0 0.4 2.4 1 1 0 1 1 1 0 Tetratricopeptide repeat Kdo PF06293.14 CRK14007.1 - 0.061 12.7 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CRK14007.1 - 0.14 10.9 0.0 0.24 10.1 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase NIR_SIR PF01077.22 CRK14007.1 - 0.14 11.7 0.0 22 4.5 0.0 2.3 2 0 0 2 2 2 0 Nitrite and sulphite reductase 4Fe-4S domain Clr5 PF14420.6 CRK14008.1 - 6.1e-18 64.8 2.7 1.1e-17 63.9 2.7 1.5 1 0 0 1 1 1 1 Clr5 domain TPR_12 PF13424.6 CRK14008.1 - 1.7e-07 31.4 9.1 2.9e-06 27.5 2.7 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 CRK14008.1 - 0.00093 19.8 3.2 0.24 12.1 0.1 3.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 CRK14008.1 - 0.0017 18.1 0.6 0.055 13.3 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 CRK14008.1 - 0.0019 18.2 0.3 0.16 12.2 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat RPN7 PF10602.9 CRK14008.1 - 0.047 13.4 0.3 0.081 12.6 0.3 1.4 1 0 0 1 1 1 0 26S proteasome subunit RPN7 TPR_19 PF14559.6 CRK14008.1 - 0.077 13.5 0.4 0.32 11.6 0.2 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat DNA_primase_lrg PF04104.14 CRK14010.1 - 4.8e-66 222.9 0.0 6.7e-66 222.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit zf-FPG_IleRS PF06827.14 CRK14011.1 - 0.0069 16.2 1.3 0.29 11.0 0.1 2.8 3 0 0 3 3 3 2 Zinc finger found in FPG and IleRS Abhydrolase_3 PF07859.13 CRK14012.1 - 4.2e-24 85.6 0.2 4.8e-24 85.4 0.2 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CRK14012.1 - 0.0053 16.3 0.1 0.008 15.7 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.12 CRK14012.1 - 0.01 14.5 0.0 0.014 14.1 0.0 1.1 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) COesterase PF00135.28 CRK14012.1 - 0.084 11.7 0.2 0.11 11.3 0.2 1.1 1 0 0 1 1 1 0 Carboxylesterase family Clr5 PF14420.6 CRK14013.1 - 0.00049 20.3 0.4 0.001 19.2 0.4 1.6 1 0 0 1 1 1 1 Clr5 domain zf-CCHH PF10283.9 CRK14014.1 - 0.18 11.9 1.2 2.6 8.1 0.1 2.7 3 0 0 3 3 3 0 PBZ domain Ribonuclease_T2 PF00445.18 CRK14015.1 - 4.8e-35 121.4 0.0 6.7e-35 121.0 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family Zn_clus PF00172.18 CRK14016.1 - 3.3e-10 39.9 10.6 5.4e-10 39.2 10.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 CRK14016.1 - 3.9e-06 26.1 3.4 3.9e-06 26.1 3.4 2.3 2 1 0 2 2 2 1 Fungal specific transcription factor domain MBOAT PF03062.19 CRK14017.1 - 6.2e-40 137.6 4.5 2.1e-39 135.8 0.6 2.3 2 0 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family Pex14_N PF04695.13 CRK14017.1 - 0.11 13.2 1.7 16 6.1 0.0 3.0 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Bac_rhamnosid6H PF17389.2 CRK14018.1 - 2.3e-13 50.1 1.2 4.4e-13 49.2 1.2 1.3 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Trehalase PF01204.18 CRK14018.1 - 5.8e-06 25.4 0.4 9e-06 24.8 0.4 1.2 1 0 0 1 1 1 1 Trehalase Bac_rhamnosid_C PF17390.2 CRK14018.1 - 0.015 15.1 0.1 0.041 13.7 0.1 1.7 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase C-terminal domain GDE_C PF06202.14 CRK14018.1 - 0.032 13.2 1.9 0.083 11.8 1.9 1.7 1 1 0 1 1 1 0 Amylo-alpha-1,6-glucosidase HSP90 PF00183.18 CRK14021.1 - 1.6e-220 733.4 31.5 2e-220 733.1 31.5 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 CRK14021.1 - 1.6e-14 54.4 0.1 3.1e-14 53.4 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CRK14021.1 - 8.2e-09 35.4 0.1 8.2e-09 35.4 0.1 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LOH1CR12 PF10158.9 CRK14021.1 - 0.037 14.1 0.3 0.14 12.2 0.3 2.0 1 0 0 1 1 1 0 Tumour suppressor protein Flavin_Reduct PF01613.18 CRK14022.1 - 2.5e-33 115.3 0.0 3.9e-33 114.7 0.0 1.3 1 0 0 1 1 1 1 Flavin reductase like domain Ribosomal_L31 PF01197.18 CRK14023.1 - 2.4e-05 24.5 0.0 4e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L31 Flavin_Reduct PF01613.18 CRK14024.1 - 3.9e-34 117.9 0.0 5.5e-34 117.5 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain Ribosomal_L31 PF01197.18 CRK14025.1 - 2.4e-05 24.5 0.0 4.3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L31 Vps5 PF09325.10 CRK14026.1 - 2.6e-71 239.9 6.5 3e-71 239.7 6.5 1.0 1 0 0 1 1 1 1 Vps5 C terminal like BAR_3_WASP_bdg PF10456.9 CRK14026.1 - 0.00018 21.0 1.5 0.01 15.3 0.1 2.1 1 1 1 2 2 2 2 WASP-binding domain of Sorting nexin protein DUF3450 PF11932.8 CRK14026.1 - 0.0073 15.6 4.1 0.011 15.0 4.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) BAR_2 PF10455.9 CRK14026.1 - 0.0075 15.4 1.7 0.0088 15.2 1.7 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking DUF745 PF05335.13 CRK14026.1 - 0.014 15.2 3.3 0.022 14.5 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) DUF713 PF05218.14 CRK14026.1 - 0.049 13.4 6.1 0.031 14.0 2.1 2.0 1 1 2 3 3 3 0 Protein of unknown function (DUF713) Mod_r PF07200.13 CRK14026.1 - 0.22 11.6 6.9 0.35 11.0 6.2 1.8 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Vps5 PF09325.10 CRK14027.1 - 5.1e-87 291.3 4.6 5.1e-87 291.3 4.6 1.5 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.24 CRK14027.1 - 5.7e-21 74.6 0.0 1.4e-20 73.4 0.0 1.6 1 0 0 1 1 1 1 PX domain SKG6 PF08693.10 CRK14027.1 - 1.5e-06 27.5 0.1 2.7e-06 26.7 0.1 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain BAR_3 PF16746.5 CRK14027.1 - 0.0029 17.3 6.3 0.078 12.7 2.1 2.4 1 1 1 2 2 2 2 BAR domain of APPL family BAR_3_WASP_bdg PF10456.9 CRK14027.1 - 0.0059 16.1 1.5 0.063 12.7 1.4 2.1 1 1 0 1 1 1 1 WASP-binding domain of Sorting nexin protein DUF3450 PF11932.8 CRK14027.1 - 0.047 13.0 4.1 0.12 11.7 4.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) BAR_2 PF10455.9 CRK14027.1 - 0.062 12.4 1.6 0.11 11.6 1.6 1.4 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking DUF713 PF05218.14 CRK14027.1 - 0.31 10.7 4.5 1.4 8.7 4.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF713) DUF745 PF05335.13 CRK14027.1 - 1.1 9.0 7.0 0.22 11.2 3.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF745) PGF-CTERM PF18204.1 CRK14027.1 - 1.4 9.0 6.3 2.5 8.2 6.3 1.5 1 0 0 1 1 1 0 PGF-CTERM motif RAP1 PF07218.11 CRK14027.1 - 6.4 4.9 6.1 11 4.1 6.1 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Mod_r PF07200.13 CRK14027.1 - 9.1 6.4 9.1 2.4 8.3 5.6 1.8 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein PX PF00787.24 CRK14028.1 - 2.4e-22 79.0 0.0 3.6e-22 78.5 0.0 1.3 1 0 0 1 1 1 1 PX domain Lipase_GDSL PF00657.22 CRK14028.1 - 0.076 13.0 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Filament_head PF04732.14 CRK14028.1 - 0.51 11.2 7.2 0.14 13.1 2.7 2.1 2 0 0 2 2 2 0 Intermediate filament head (DNA binding) region SKG6 PF08693.10 CRK14029.1 - 1.7e-06 27.4 0.1 1.7e-06 27.4 0.1 1.7 2 0 0 2 2 2 1 Transmembrane alpha-helix domain PGF-CTERM PF18204.1 CRK14029.1 - 0.54 10.3 6.3 1 9.4 6.3 1.5 1 0 0 1 1 1 0 PGF-CTERM motif WD40 PF00400.32 CRK14030.1 - 3.5e-71 233.3 49.8 1.1e-08 35.5 1.7 12.2 11 1 0 11 11 11 11 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 CRK14030.1 - 1.2e-38 132.3 0.0 1.7e-38 131.8 0.0 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 CRK14030.1 - 5.1e-28 97.2 2.7 0.021 15.1 0.0 9.4 4 3 5 9 9 9 8 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CRK14030.1 - 1e-09 38.5 0.9 0.0028 17.6 0.0 4.8 3 1 2 5 5 5 3 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.11 CRK14030.1 - 1.5e-08 33.8 0.0 5.7 5.6 0.0 6.3 5 2 2 7 7 7 3 Nup133 N terminal like RAB3GAP2_N PF14655.6 CRK14030.1 - 1.3e-07 31.3 0.0 3 7.0 0.0 4.7 4 2 0 4 4 4 4 Rab3 GTPase-activating protein regulatory subunit N-terminus LisH PF08513.11 CRK14030.1 - 1.3e-05 24.9 0.0 2.4e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 LisH Nup160 PF11715.8 CRK14030.1 - 0.00065 18.5 2.7 10 4.6 0.1 4.7 5 0 0 5 5 5 1 Nucleoporin Nup120/160 Asp_Arg_Hydrox PF05118.15 CRK14030.1 - 0.035 13.9 0.0 84 3.0 0.0 3.5 4 0 0 4 4 4 0 Aspartyl/Asparaginyl beta-hydroxylase Ge1_WD40 PF16529.5 CRK14030.1 - 0.045 12.7 1.3 83 2.0 0.0 5.7 5 3 4 9 9 9 0 WD40 region of Ge1, enhancer of mRNA-decapping protein TFIIIC_delta PF12657.7 CRK14030.1 - 0.16 11.9 0.0 0.51 10.2 0.0 1.8 1 0 0 1 1 1 0 Transcription factor IIIC subunit delta N-term WD40_like PF17005.5 CRK14030.1 - 0.17 11.2 0.0 51 3.0 0.0 3.5 4 0 0 4 4 4 0 WD40-like domain SdiA-regulated PF06977.11 CRK14030.1 - 0.18 11.0 0.0 8.9 5.5 0.0 2.3 2 0 0 2 2 2 0 SdiA-regulated nos_propeller PF18764.1 CRK14030.1 - 0.27 11.2 1.9 39 4.3 0.0 4.3 5 0 0 5 5 5 0 Nitrous oxide reductase propeller repeat DUF5122 PF17164.4 CRK14030.1 - 0.41 11.0 6.0 68 3.9 0.1 3.9 3 0 0 3 3 3 0 Domain of unknown function (DUF5122) beta-propeller Med11 PF10280.9 CRK14031.1 - 2.9e-46 157.3 0.1 3.9e-46 156.9 0.1 1.2 1 0 0 1 1 1 1 Mediator complex protein GPS2_interact PF15784.5 CRK14031.1 - 0.038 14.4 0.5 0.39 11.2 0.1 2.2 1 1 1 2 2 2 0 G-protein pathway suppressor 2-interacting domain Utp11 PF03998.13 CRK14032.1 - 0.17 11.8 0.4 0.29 11.0 0.4 1.2 1 0 0 1 1 1 0 Utp11 protein Med11 PF10280.9 CRK14033.1 - 3.1e-46 157.2 0.1 4e-46 156.9 0.1 1.2 1 0 0 1 1 1 1 Mediator complex protein GPS2_interact PF15784.5 CRK14033.1 - 0.045 14.2 0.3 0.29 11.6 0.1 2.0 1 1 1 2 2 2 0 G-protein pathway suppressor 2-interacting domain SF1-HH PF16275.5 CRK14034.1 - 5.2e-87 287.7 15.5 1.6e-43 147.6 1.0 3.3 2 1 1 3 3 3 2 Splicing factor 1 helix-hairpin domain Peptidase_M28 PF04389.17 CRK14034.1 - 8.7e-36 123.5 0.0 1.6e-35 122.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 zf-CCHC PF00098.23 CRK14034.1 - 1.4e-21 75.5 30.2 5e-05 23.2 0.8 4.4 4 0 0 4 4 4 4 Zinc knuckle KH_1 PF00013.29 CRK14034.1 - 1.1e-16 60.4 6.3 1.5e-07 31.1 0.2 3.5 3 0 0 3 3 3 2 KH domain zf-CCHC_3 PF13917.6 CRK14034.1 - 4.3e-11 42.6 20.9 0.0024 17.8 3.9 4.5 2 2 2 4 4 4 4 Zinc knuckle zf-CCHC_6 PF15288.6 CRK14034.1 - 3.3e-07 30.0 21.0 0.11 12.3 0.3 4.6 2 2 2 4 4 4 4 Zinc knuckle zf-CCHC_4 PF14392.6 CRK14034.1 - 5.7e-05 22.8 17.6 1.6 8.5 0.4 4.5 4 0 0 4 4 4 4 Zinc knuckle Peptidase_M20 PF01546.28 CRK14034.1 - 0.00095 18.9 0.0 0.0019 17.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Prim_Zn_Ribbon PF08273.12 CRK14034.1 - 0.0055 17.0 11.6 0.67 10.3 2.2 3.0 2 0 0 2 2 2 2 Zinc-binding domain of primase-helicase KH_5 PF13184.6 CRK14034.1 - 0.11 12.6 0.1 36 4.5 0.0 2.9 2 0 0 2 2 2 0 NusA-like KH domain TPH PF13868.6 CRK14034.1 - 0.15 10.5 1.6 8.2 4.8 0.1 2.2 2 0 0 2 2 2 0 Trichohyalin-plectin-homology domain zf-CCHC_2 PF13696.6 CRK14034.1 - 0.22 11.4 27.2 0.053 13.4 0.5 4.3 4 0 0 4 4 4 0 Zinc knuckle CCDC23 PF15674.5 CRK14034.1 - 0.28 11.2 2.0 25 5.0 0.2 2.6 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 23 PHD_4 PF16866.5 CRK14034.1 - 0.36 11.0 11.7 3.6 7.7 2.2 2.6 2 0 0 2 2 2 0 PHD-finger zf-CHY PF05495.12 CRK14034.1 - 0.49 10.9 10.8 5.3 7.6 1.5 2.9 2 2 0 2 2 2 0 CHY zinc finger UPF0167 PF03691.14 CRK14034.1 - 6.5 6.5 7.4 24 4.7 0.9 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0167) zinc-ribbons_6 PF07191.12 CRK14034.1 - 7.1 6.7 12.5 15 5.7 2.5 2.5 2 0 0 2 2 2 0 zinc-ribbons Metallophos PF00149.28 CRK14035.1 - 2.3e-17 64.2 0.2 4.2e-17 63.3 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase GST_N PF02798.20 CRK14035.1 - 1.3e-13 51.1 0.0 3.5e-13 49.7 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 CRK14035.1 - 2.4e-12 47.1 0.0 8e-12 45.4 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CRK14035.1 - 8.4e-11 42.0 0.0 2.5e-10 40.5 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 CRK14035.1 - 2.8e-09 37.1 0.0 6.9e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CRK14035.1 - 3.3e-08 33.6 0.0 7.9e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CRK14035.1 - 3.5e-08 33.3 0.9 7.8e-08 32.2 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Metallophos_2 PF12850.7 CRK14035.1 - 7.6e-05 23.0 0.0 0.00057 20.1 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain SE PF08491.10 CRK14036.1 - 1.2e-16 60.6 0.0 1.8e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.24 CRK14036.1 - 4.4e-11 42.9 0.6 1.8e-06 27.8 0.2 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 CRK14036.1 - 1.3e-06 27.9 0.2 1.6e-05 24.3 0.2 2.1 1 1 0 1 1 1 1 FAD binding domain GIDA PF01134.22 CRK14036.1 - 1.1e-05 24.7 0.2 0.0032 16.6 0.2 2.0 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_8 PF13450.6 CRK14036.1 - 2.6e-05 24.4 0.5 7.7e-05 22.9 0.4 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CRK14036.1 - 0.00017 21.0 0.0 0.00026 20.3 0.0 1.2 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 CRK14036.1 - 0.00049 19.3 0.4 0.0017 17.5 0.2 1.8 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 CRK14036.1 - 0.00072 19.0 0.8 0.00091 18.7 0.2 1.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CRK14036.1 - 0.0048 16.2 0.1 0.0083 15.4 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 CRK14036.1 - 0.012 15.2 0.1 0.021 14.5 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 CRK14036.1 - 0.023 15.2 0.4 0.092 13.3 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.23 CRK14036.1 - 0.031 14.3 0.0 0.052 13.5 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus HI0933_like PF03486.14 CRK14036.1 - 0.041 12.6 0.1 0.059 12.1 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.12 CRK14036.1 - 0.099 11.7 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein 3HCDH_N PF02737.18 CRK14036.1 - 0.12 12.3 0.1 0.2 11.5 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HD_3 PF13023.6 CRK14040.1 - 3.9e-10 39.9 0.0 3.9e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 HD domain BAH PF01426.18 CRK14041.1 - 4.9e-12 45.8 0.0 9.1e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 BAH domain PHD PF00628.29 CRK14041.1 - 1.3e-07 31.4 8.0 2.8e-07 30.3 8.0 1.5 1 0 0 1 1 1 1 PHD-finger DNA_binding_2 PF13724.6 CRK14041.1 - 0.0066 16.8 0.3 0.021 15.2 0.3 1.8 1 0 0 1 1 1 1 DNA-binding domain DUF2318 PF10080.9 CRK14041.1 - 0.053 13.6 3.0 0.1 12.7 3.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) Zf_RING PF16744.5 CRK14041.1 - 0.27 11.4 13.5 3.3 7.9 13.5 2.2 1 1 0 1 1 1 0 KIAA1045 RING finger C1_1 PF00130.22 CRK14041.1 - 2.9 7.8 13.8 0.56 10.1 7.4 2.3 1 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) AAA_lid_10 PF17872.1 CRK14043.1 - 6.5e-08 32.6 0.1 1.9e-07 31.1 0.0 1.8 2 0 0 2 2 2 1 AAA lid domain Cdc6_C PF09079.11 CRK14043.1 - 2.1e-06 27.6 0.1 3e-05 23.9 0.1 2.6 2 1 0 2 2 2 1 CDC6, C terminal winged helix domain Minor_tail_Z PF06763.11 CRK14043.1 - 0.055 13.3 0.8 0.099 12.4 0.8 1.4 1 0 0 1 1 1 0 Prophage minor tail protein Z (GPZ) TPR_12 PF13424.6 CRK14043.1 - 0.071 13.4 1.1 0.14 12.5 0.1 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat MCLC PF05934.11 CRK14043.1 - 0.085 11.6 0.8 0.11 11.2 0.8 1.1 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) Glyco_transf_64 PF09258.10 CRK14045.1 - 2.9e-40 138.1 0.1 8.9e-35 120.1 0.0 2.1 1 1 1 2 2 2 2 Glycosyl transferase family 64 domain Ank_4 PF13637.6 CRK14046.1 - 0.0028 18.2 0.0 0.0055 17.3 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) DASH_Spc19 PF08287.11 CRK14062.1 - 4.5e-24 85.1 0.0 4.5e-24 85.1 0.0 1.3 2 0 0 2 2 2 1 Spc19 SH3_1 PF00018.28 CRK14063.1 - 2.4e-08 33.4 0.1 3.9e-08 32.8 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CRK14063.1 - 5.5e-06 26.0 0.0 9.3e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 CRK14063.1 - 9.7e-06 25.4 0.0 1.7e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Dynactin_p22 PF07426.11 CRK14063.1 - 1.1e-05 25.3 0.0 1.6e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Dynactin subunit p22 Aa_trans PF01490.18 CRK14065.1 - 3.1e-17 62.4 5.3 3.4e-17 62.2 5.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CRK14065.1 - 0.0021 17.1 2.8 0.0024 17.0 2.8 1.0 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family Ribosomal_S16 PF00886.19 CRK14068.1 - 4.1e-13 49.2 0.1 1.9e-12 47.0 0.1 1.8 1 1 0 1 1 1 1 Ribosomal protein S16 WD40 PF00400.32 CRK14085.1 - 9.5e-06 26.3 7.2 2.3 9.2 0.1 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.8 CRK14085.1 - 0.064 11.9 0.8 0.32 9.6 0.1 2.3 2 1 0 2 2 2 0 Nucleoporin Nup120/160 Mcl1_mid PF12341.8 CRK14087.1 - 2e-78 263.7 0.0 4.6e-78 262.6 0.0 1.6 2 0 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region ANAPC4_WD40 PF12894.7 CRK14087.1 - 4.1e-17 62.2 0.0 6.8e-07 29.5 0.0 5.4 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CRK14087.1 - 6.2e-16 58.5 3.0 5.8e-08 33.3 0.0 5.3 5 0 0 5 5 5 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 CRK14087.1 - 0.00063 18.8 0.0 0.48 9.3 0.0 2.6 2 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Coatomer_WDAD PF04053.14 CRK14087.1 - 0.002 17.2 0.0 0.003 16.7 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region eIF2A PF08662.11 CRK14087.1 - 0.0059 16.5 0.0 0.029 14.2 0.1 2.1 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A KTSC PF13619.6 CRK14087.1 - 0.053 13.3 0.0 5.1 7.0 0.0 2.7 2 0 0 2 2 2 0 KTSC domain IKI3 PF04762.12 CRK14087.1 - 0.056 11.4 0.0 0.091 10.7 0.0 1.2 1 0 0 1 1 1 0 IKI3 family WDCP PF15390.6 CRK14087.1 - 0.074 11.4 0.0 1.2 7.4 0.3 2.0 1 1 1 2 2 2 0 WD repeat and coiled-coil-containing protein family PD40 PF07676.12 CRK14087.1 - 0.075 13.0 1.1 40 4.3 0.1 4.0 3 1 1 4 4 4 0 WD40-like Beta Propeller Repeat MMS1_N PF10433.9 CRK14087.1 - 0.11 11.1 0.0 0.66 8.5 0.0 2.0 2 0 0 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term DNA_pol_alpha_N PF12254.8 CRK14087.1 - 0.2 11.8 4.9 0.56 10.3 4.9 1.7 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal DnaJ PF00226.31 CRK14089.1 - 9.4e-18 64.1 1.6 1.8e-17 63.2 1.6 1.5 1 0 0 1 1 1 1 DnaJ domain DUF1931 PF09123.11 CRK14089.1 - 0.061 13.4 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1931) Sugar_tr PF00083.24 CRK14091.1 - 4.6e-34 118.1 24.9 1.1e-17 64.1 8.0 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CRK14091.1 - 8.4e-10 38.1 36.0 3.1e-06 26.4 25.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.18 CRK14092.1 - 0.28 11.3 7.0 0.61 10.3 7.0 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Ppx-GppA PF02541.16 CRK14093.1 - 3e-29 102.3 0.0 5e-29 101.6 0.0 1.3 1 0 0 1 1 1 1 Ppx/GppA phosphatase family BTB PF00651.31 CRK14095.1 - 0.013 15.7 0.0 0.029 14.6 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain Meth_synt_2 PF01717.18 CRK14096.1 - 1.5e-146 487.8 0.0 7.7e-142 472.3 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 CRK14096.1 - 6e-118 393.9 0.0 2.2e-111 372.4 0.0 2.8 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.17 CRK14096.1 - 0.00051 19.3 0.0 0.02 14.1 0.0 2.3 2 0 0 2 2 2 2 Uroporphyrinogen decarboxylase (URO-D) Oxidored_FMN PF00724.20 CRK14097.1 - 8.8e-63 212.6 0.0 4.6e-60 203.7 0.0 2.1 1 1 1 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family PTS_IIB PF02302.17 CRK14097.1 - 0.011 16.4 0.2 0.029 15.0 0.0 1.8 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIB subunit Peptidase_C15 PF01470.17 CRK14098.1 - 1.2e-11 45.1 0.0 0.00011 22.5 0.0 2.8 2 1 0 2 2 2 2 Pyroglutamyl peptidase HhH-GPD PF00730.25 CRK14099.1 - 0.00054 20.4 0.0 0.0009 19.7 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein RRM_1 PF00076.22 CRK14100.1 - 3.3e-19 68.5 0.3 5.2e-19 67.8 0.3 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CRK14100.1 - 2.3e-05 24.0 0.0 2.5e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Frankia_peptide PF14407.6 CRK14100.1 - 0.019 14.9 0.0 0.35 10.9 0.0 2.3 2 1 0 2 2 2 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. RRM_occluded PF16842.5 CRK14100.1 - 0.02 14.7 0.0 0.029 14.2 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif Serglycin PF04360.12 CRK14101.1 - 0.13 12.2 4.5 0.28 11.1 4.5 1.5 1 0 0 1 1 1 0 Serglycin Mg_trans_NIPA PF05653.14 CRK14101.1 - 0.16 11.0 0.0 0.23 10.5 0.0 1.1 1 0 0 1 1 1 0 Magnesium transporter NIPA HeLo PF14479.6 CRK14102.1 - 2.5e-42 145.1 0.1 4e-42 144.4 0.1 1.3 1 0 0 1 1 1 1 Prion-inhibition and propagation SURF4 PF02077.15 CRK14103.1 - 8.9e-96 320.6 7.8 1e-95 320.4 7.8 1.0 1 0 0 1 1 1 1 SURF4 family Halogen_Hydrol PF10112.9 CRK14103.1 - 0.84 9.6 6.1 5 7.1 2.1 2.5 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein CD99L2 PF12301.8 CRK14104.1 - 0.0083 16.4 0.8 0.0083 16.4 0.8 2.3 2 0 0 2 2 2 1 CD99 antigen like protein 2 Shisa PF13908.6 CRK14104.1 - 0.92 9.7 3.8 18 5.5 0.0 2.5 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator VSP PF03302.13 CRK14104.1 - 1.1 8.0 3.2 2.1 7.1 3.2 1.4 1 0 0 1 1 1 0 Giardia variant-specific surface protein RRM_1 PF00076.22 CRK14105.1 - 4.1e-28 97.0 0.1 8.7e-12 44.7 0.0 4.4 4 1 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_S13_N PF08069.12 CRK14106.1 - 9.1e-31 105.7 0.2 1.5e-30 105.0 0.2 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 CRK14106.1 - 4.6e-15 55.6 0.2 6.6e-15 55.1 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.18 CRK14106.1 - 0.068 13.1 0.1 0.18 11.8 0.0 1.7 2 0 0 2 2 2 0 'Paired box' domain Dpy-30 PF05186.13 CRK14107.1 - 1.4e-16 59.9 0.1 2e-16 59.4 0.1 1.3 1 0 0 1 1 1 1 Dpy-30 motif Ribosomal_S13_N PF08069.12 CRK14108.1 - 2.3e-21 75.6 0.3 1e-20 73.5 0.1 2.1 2 0 0 2 2 2 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 CRK14108.1 - 1.6e-14 53.8 0.2 2.9e-14 53.0 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S15 Dpy-30 PF05186.13 CRK14109.1 - 1.3e-16 60.0 0.1 2e-16 59.4 0.1 1.3 1 0 0 1 1 1 1 Dpy-30 motif VRR_NUC PF08774.11 CRK14110.1 - 8.2e-23 80.5 0.0 1.9e-22 79.4 0.0 1.6 1 0 0 1 1 1 1 VRR-NUC domain Nicastrin PF05450.15 CRK14111.1 - 0.57 9.6 0.0 0.57 9.6 0.0 2.1 3 0 0 3 3 3 0 Nicastrin Nicastrin PF05450.15 CRK14113.1 - 1.6 8.1 3.5 0.75 9.2 0.1 2.1 3 0 0 3 3 3 0 Nicastrin DLEU7 PF15760.5 CRK14117.1 - 6.8 6.1 9.5 0.86 9.1 3.6 2.1 1 1 1 2 2 2 0 Leukemia-associated protein 7 APH PF01636.23 CRK14118.1 - 1.5e-54 185.5 1.5 3e-39 135.4 0.2 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family EcKinase PF02958.20 CRK14118.1 - 2.4e-08 33.6 0.0 0.0005 19.5 0.0 2.2 2 0 0 2 2 2 2 Ecdysteroid kinase Kdo PF06293.14 CRK14118.1 - 0.00033 20.1 0.1 0.11 11.8 0.0 3.0 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family Fructosamin_kin PF03881.14 CRK14118.1 - 0.00055 19.2 0.0 0.15 11.2 0.0 3.0 2 1 0 2 2 2 1 Fructosamine kinase RIO1 PF01163.22 CRK14118.1 - 0.009 15.6 0.0 1.3 8.6 0.0 3.0 3 0 0 3 3 3 1 RIO1 family MHC_II_alpha PF00993.20 CRK14118.1 - 0.16 11.7 0.3 19 5.0 0.1 2.4 2 0 0 2 2 2 0 Class II histocompatibility antigen, alpha domain Retinal PF15449.6 CRK14119.1 - 0.048 11.5 0.0 0.069 10.9 0.0 1.1 1 0 0 1 1 1 0 Retinal protein Mad3_BUB1_I PF08311.12 CRK14120.1 - 1.9e-42 144.2 0.6 3e-42 143.5 0.6 1.3 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.25 CRK14120.1 - 8.6e-09 35.1 0.0 1.3e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 CRK14120.1 - 0.028 13.8 0.0 0.062 12.6 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mad3_BUB1_I_2 PF17014.5 CRK14120.1 - 0.053 13.6 0.0 0.098 12.8 0.0 1.3 1 0 0 1 1 1 0 Putative Mad3/BUB1 like region 1 protein Pkinase_Tyr PF07714.17 CRK14120.1 - 0.15 11.3 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Kinase-like PF14531.6 CRK14120.1 - 0.17 11.2 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Kinase-like AP_endonuc_2 PF01261.24 CRK14121.1 - 8.9e-19 67.8 1.2 2.8e-16 59.6 0.7 2.3 1 1 1 2 2 2 2 Xylose isomerase-like TIM barrel CDC45 PF02724.14 CRK14121.1 - 0.99 7.6 9.0 2.8 6.1 0.3 2.1 2 0 0 2 2 2 0 CDC45-like protein DUF5427 PF10310.9 CRK14121.1 - 1.3 7.9 23.3 0.31 9.9 10.8 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5427) SRP-alpha_N PF04086.13 CRK14121.1 - 5.1 6.9 23.9 5.6 6.8 11.5 2.2 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal DAGAT PF03982.13 CRK14122.1 - 1.6e-46 158.5 0.0 2.2e-46 158.1 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase AP_endonuc_2 PF01261.24 CRK14123.1 - 3.9e-32 111.4 1.6 5.8e-32 110.8 1.6 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel CDC45 PF02724.14 CRK14123.1 - 1.9 6.7 11.1 2.6 6.3 0.4 2.1 2 0 0 2 2 2 0 CDC45-like protein DAGAT PF03982.13 CRK14124.1 - 3.5e-88 295.3 0.0 5.7e-88 294.7 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Rer1 PF03248.13 CRK14124.1 - 0.035 13.8 0.0 0.065 13.0 0.0 1.4 1 0 0 1 1 1 0 Rer1 family Kelch_4 PF13418.6 CRK14125.1 - 9.8e-22 76.7 2.7 2.8e-07 30.4 0.0 3.3 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_3 PF13415.6 CRK14125.1 - 5.5e-21 74.3 1.2 1.8e-08 34.5 0.0 3.2 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_5 PF13854.6 CRK14125.1 - 3.2e-17 62.1 0.8 3.4e-08 33.3 0.0 3.4 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.6 CRK14125.1 - 3.8e-16 58.7 1.7 5e-05 23.4 0.2 3.2 3 0 0 3 3 3 3 Kelch motif Kelch_2 PF07646.15 CRK14125.1 - 8.7e-11 41.4 2.2 0.0027 17.6 0.0 3.9 3 1 0 3 3 3 3 Kelch motif Kelch_1 PF01344.25 CRK14125.1 - 4.1e-10 39.1 2.3 0.0014 18.1 0.0 3.8 3 1 0 3 3 3 3 Kelch motif WLM PF08325.10 CRK14127.1 - 2.2e-27 96.4 0.0 7.3e-27 94.7 0.0 1.9 1 1 0 1 1 1 1 WLM domain DUF45 PF01863.17 CRK14127.1 - 9.1e-08 32.4 0.6 2.5e-07 31.0 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function DUF45 HpuA PF16960.5 CRK14127.1 - 0.063 12.4 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Haemoglobin-haptoglobin utilisation, porphyrin transporter zf-HIT PF04438.16 CRK14128.1 - 2.8e-09 36.7 5.0 2.8e-09 36.7 5.0 1.7 2 0 0 2 2 2 1 HIT zinc finger Med3 PF11593.8 CRK14128.1 - 2 7.5 13.1 2.4 7.3 13.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal FXMRP1_C_core PF12235.8 CRK14128.1 - 8 7.1 10.2 18 5.9 3.8 2.3 1 1 0 2 2 2 0 Fragile X-related 1 protein core C terminal zf-HIT PF04438.16 CRK14130.1 - 1.7e-09 37.4 5.0 2.6e-09 36.8 5.0 1.3 1 0 0 1 1 1 1 HIT zinc finger zinc_ribbon_2 PF13240.6 CRK14130.1 - 0.64 9.8 2.7 21 5.0 0.3 2.5 2 0 0 2 2 2 0 zinc-ribbon domain SKA1 PF07160.12 CRK14130.1 - 1.2 8.9 3.5 1.7 8.4 3.5 1.4 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 MnhB PF04039.13 CRK14131.1 - 0.034 14.4 1.0 14 6.0 0.2 3.0 3 0 0 3 3 3 0 Domain related to MnhB subunit of Na+/H+ antiporter CENP-Q PF13094.6 CRK14131.1 - 0.31 11.2 1.7 0.46 10.7 1.7 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF4705 PF15788.5 CRK14131.1 - 0.74 10.1 7.9 11 6.4 1.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4705) DUF4536 PF15055.6 CRK14131.1 - 3.4 8.0 6.3 33 4.8 0.6 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4536) Thioredoxin_6 PF13848.6 CRK14132.1 - 3.5e-39 134.6 0.1 3.6e-29 102.0 0.1 2.2 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.20 CRK14132.1 - 1.5e-32 111.6 1.7 1.5e-31 108.4 0.1 2.8 3 0 0 3 3 3 1 Thioredoxin Calsequestrin PF01216.17 CRK14132.1 - 3.1e-09 36.4 0.6 4.6e-09 35.8 0.6 1.2 1 0 0 1 1 1 1 Calsequestrin Thioredoxin_8 PF13905.6 CRK14132.1 - 6.6e-05 23.2 0.1 0.031 14.6 0.0 3.4 2 2 1 3 3 3 1 Thioredoxin-like Thioredoxin_2 PF13098.6 CRK14132.1 - 0.00051 20.5 0.0 0.0017 18.8 0.0 1.9 1 0 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 CRK14132.1 - 0.0016 18.4 0.3 0.0057 16.6 0.1 1.9 2 0 0 2 2 2 1 AhpC/TSA family OST3_OST6 PF04756.13 CRK14132.1 - 0.002 17.5 0.2 0.0044 16.4 0.0 1.7 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 CRK14132.1 - 0.021 15.0 0.0 0.13 12.5 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin-like Thioredoxin_3 PF13192.6 CRK14132.1 - 0.043 13.9 0.0 0.17 12.0 0.0 2.0 1 0 0 1 1 1 0 Thioredoxin domain Redoxin PF08534.10 CRK14132.1 - 0.12 12.1 0.8 2.1 8.0 0.1 2.5 2 0 0 2 2 2 0 Redoxin Thioredoxin PF00085.20 CRK14133.1 - 4.1e-61 203.4 6.0 3e-31 107.5 0.1 4.0 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 CRK14133.1 - 1.8e-49 168.2 0.9 6.2e-38 130.6 0.6 3.4 2 2 1 3 3 3 2 Thioredoxin-like domain Calsequestrin PF01216.17 CRK14133.1 - 4.5e-09 35.8 3.9 6.3e-09 35.4 0.7 2.4 1 1 2 3 3 3 1 Calsequestrin Thioredoxin_8 PF13905.6 CRK14133.1 - 5e-09 36.4 0.1 0.073 13.4 0.0 4.6 3 3 1 4 4 4 2 Thioredoxin-like OST3_OST6 PF04756.13 CRK14133.1 - 4.9e-08 32.7 0.8 0.0092 15.4 0.0 3.3 2 1 1 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 CRK14133.1 - 1.1e-07 31.9 0.0 0.0068 16.6 0.0 3.2 3 0 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.21 CRK14133.1 - 2.6e-07 30.6 1.0 0.01 15.7 0.1 2.9 3 0 0 3 3 3 2 AhpC/TSA family Thioredoxin_2 PF13098.6 CRK14133.1 - 2.6e-07 31.1 1.4 0.0031 17.9 0.0 3.4 3 1 0 3 3 3 2 Thioredoxin-like domain Redoxin PF08534.10 CRK14133.1 - 1e-06 28.5 2.0 0.0029 17.3 0.0 3.4 3 0 0 3 3 3 2 Redoxin DSBA PF01323.20 CRK14133.1 - 0.033 14.0 0.4 15 5.3 0.1 3.5 3 1 0 3 3 3 0 DSBA-like thioredoxin domain Thioredoxin_3 PF13192.6 CRK14133.1 - 0.033 14.2 0.1 0.29 11.2 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin domain Thioredoxin_4 PF13462.6 CRK14133.1 - 1.1 9.4 7.8 2.8 8.1 0.2 3.7 4 2 0 4 4 4 0 Thioredoxin 3HCDH PF00725.22 CRK14134.1 - 0.22 12.1 0.0 0.5 11.0 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Mon1 PF03164.14 CRK14135.1 - 4.2e-152 506.9 0.0 4.9e-152 506.7 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 Exo_endo_phos_2 PF14529.6 CRK14135.1 - 0.074 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase Dopey_N PF04118.14 CRK14136.1 - 1.8e-116 388.6 0.0 4.8e-116 387.2 0.0 1.8 2 0 0 2 2 2 1 Dopey, N-terminal MazG PF03819.17 CRK14136.1 - 0.041 14.0 0.0 1.4 9.1 0.0 3.2 3 0 0 3 3 3 0 MazG nucleotide pyrophosphohydrolase domain DAD PF02109.16 CRK14138.1 - 4.3e-48 162.1 0.9 5.2e-48 161.9 0.9 1.1 1 0 0 1 1 1 1 DAD family Tmemb_14 PF03647.13 CRK14140.1 - 1.5e-23 83.3 7.5 1.7e-23 83.1 7.5 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C CytB6-F_Fe-S PF08802.10 CRK14140.1 - 5.9 7.0 10.1 7.9 6.6 0.4 3.0 4 0 0 4 4 4 0 Cytochrome B6-F complex Fe-S subunit Trehalase PF01204.18 CRK14141.1 - 2.9e-59 201.3 0.0 3.8e-59 200.9 0.0 1.1 1 0 0 1 1 1 1 Trehalase Cmc1 PF08583.10 CRK14141.1 - 3.3e-10 39.8 0.7 6.2e-10 39.0 0.7 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like GDE_C PF06202.14 CRK14141.1 - 0.096 11.6 0.1 0.15 11.0 0.1 1.2 1 0 0 1 1 1 0 Amylo-alpha-1,6-glucosidase Trehalase PF01204.18 CRK14142.1 - 1.2e-108 364.2 4.9 6.3e-108 361.8 4.9 1.8 1 1 0 1 1 1 1 Trehalase Beta_elim_lyase PF01212.21 CRK14142.1 - 6.9e-66 222.5 0.0 9.9e-66 222.0 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 CRK14142.1 - 0.00024 19.8 0.0 0.00043 18.9 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme MFS_1 PF07690.16 CRK14143.1 - 1e-37 129.9 60.2 4.4e-37 127.8 40.2 2.6 1 1 2 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK14143.1 - 1.7e-18 66.7 32.7 3.2e-10 39.5 8.6 3.1 2 1 1 3 3 3 2 Sugar (and other) transporter HPIH PF13323.6 CRK14145.1 - 2.3e-52 177.0 2.8 4.2e-52 176.1 2.8 1.5 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.8 CRK14145.1 - 1.9e-11 44.1 6.8 7.8e-10 38.8 6.8 2.5 1 1 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation HMG-CoA_red PF00368.18 CRK14145.1 - 2.6e-11 43.1 0.0 4e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Patched PF02460.18 CRK14145.1 - 1.5e-05 23.3 1.9 2.2e-05 22.8 1.9 1.2 1 0 0 1 1 1 1 Patched family Lig_chan PF00060.26 CRK14145.1 - 0.83 9.5 6.6 2.9 7.7 0.1 3.0 2 1 0 2 2 2 0 Ligand-gated ion channel Zn_clus PF00172.18 CRK14148.1 - 7.2e-07 29.2 7.5 1e-06 28.7 7.5 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GMC_oxred_N PF00732.19 CRK14156.1 - 2.7e-70 237.1 0.0 4e-70 236.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CRK14156.1 - 6.1e-31 107.9 0.0 1.3e-30 106.8 0.0 1.6 1 1 0 1 1 1 1 GMC oxidoreductase DUF1593 PF07632.11 CRK14160.1 - 4.9e-56 190.0 0.0 5.4e-56 189.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) CSTF1_dimer PF16699.5 CRK14160.1 - 0.034 13.9 0.0 0.068 12.9 0.0 1.4 1 0 0 1 1 1 0 Cleavage stimulation factor subunit 1, dimerisation domain VRR_NUC PF08774.11 CRK14178.1 - 4.6e-23 81.4 0.0 1e-22 80.2 0.0 1.6 1 0 0 1 1 1 1 VRR-NUC domain Catalase PF00199.19 CRK14193.1 - 4.5e-60 203.8 0.0 5.6e-60 203.4 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 CRK14193.1 - 1e-16 60.9 0.1 1.8e-16 60.1 0.1 1.4 1 0 0 1 1 1 1 Catalase-related immune-responsive Questin_oxidase PF14027.6 CRK14195.1 - 2.6e-61 208.0 6.7 1.6e-57 195.6 1.1 2.1 1 1 0 2 2 2 2 Questin oxidase-like Gpr1_Fun34_YaaH PF01184.19 CRK14199.1 - 4.2e-22 78.8 8.4 4.2e-22 78.8 8.4 1.4 2 0 0 2 2 2 1 GPR1/FUN34/yaaH family DUF2157 PF09925.9 CRK14199.1 - 0.0035 17.1 1.4 0.0066 16.2 1.4 1.6 1 1 0 1 1 1 1 Predicted membrane protein (DUF2157) PRIMA1 PF16101.5 CRK14199.1 - 7.6 6.6 9.9 10 6.2 8.9 1.7 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 adh_short_C2 PF13561.6 CRK14204.1 - 9e-22 77.8 0.0 9.8e-22 77.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRK14204.1 - 2.1e-13 50.2 0.1 2.5e-13 49.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase SWIRM PF04433.17 CRK14205.1 - 1.2e-15 57.6 0.3 4.9e-13 49.2 0.0 2.3 2 0 0 2 2 2 2 SWIRM domain Ras_bdg_2 PF14847.6 CRK14207.1 - 3.3e-27 94.8 0.0 5.9e-27 93.9 0.0 1.4 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_2 PF07647.17 CRK14207.1 - 3.1e-16 59.2 0.1 4.9e-16 58.6 0.1 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 CRK14207.1 - 1.1e-15 57.9 0.1 1.7e-15 57.2 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 CRK14207.1 - 7.3e-15 55.4 0.1 1.3e-14 54.6 0.1 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_4 PF18017.1 CRK14207.1 - 0.0062 16.5 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DJ-1_PfpI PF01965.24 CRK14208.1 - 8.4e-06 25.7 0.0 1.4e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family Acetyltransf_1 PF00583.25 CRK14208.1 - 0.028 14.7 0.0 0.059 13.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family CENP-C_C PF11699.8 CRK14210.1 - 2e-33 114.5 0.3 3.3e-33 113.7 0.3 1.4 1 0 0 1 1 1 1 Mif2/CENP-C like Mif2_N PF15624.6 CRK14210.1 - 1.2e-26 94.0 0.9 1.2e-26 94.0 0.9 4.1 2 1 2 4 4 4 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Cupin_2 PF07883.11 CRK14210.1 - 3.9e-07 29.7 0.0 8e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Cupin domain RNase_HII PF01351.18 CRK14211.1 - 4.9e-48 163.6 0.0 2.9e-47 161.1 0.0 1.9 1 1 0 1 1 1 1 Ribonuclease HII RHD3 PF05879.12 CRK14212.1 - 7e-267 887.4 0.9 4.2e-145 484.8 0.0 2.0 1 1 1 2 2 2 2 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 CRK14212.1 - 8.9e-10 38.3 0.2 1.5e-09 37.6 0.2 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.23 CRK14212.1 - 2.5e-06 27.6 0.0 5.7e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 CRK14212.1 - 3.2e-05 24.0 0.0 8e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase DSBA PF01323.20 CRK14212.1 - 0.002 17.9 0.5 0.005 16.6 0.1 1.8 2 0 0 2 2 2 1 DSBA-like thioredoxin domain AAA_28 PF13521.6 CRK14212.1 - 0.0022 18.2 0.0 0.0077 16.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CRK14212.1 - 0.017 15.5 0.0 0.088 13.2 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Septin PF00735.18 CRK14212.1 - 0.044 13.1 0.1 0.074 12.3 0.1 1.3 1 0 0 1 1 1 0 Septin ATP-grasp_2 PF08442.10 CRK14213.1 - 1.7e-76 256.3 0.5 1.7e-76 256.3 0.5 1.7 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 CRK14213.1 - 2.5e-25 89.1 2.2 5.1e-25 88.1 2.2 1.6 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 CRK14213.1 - 7.6e-09 35.4 0.1 2e-08 34.0 0.1 1.7 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 CRK14213.1 - 0.0014 18.4 2.0 0.023 14.5 0.1 2.7 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain OKR_DC_1_N PF03709.15 CRK14213.1 - 0.03 14.6 0.6 0.56 10.5 0.2 2.5 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, N-terminal domain Fructosamin_kin PF03881.14 CRK14216.1 - 4.4e-70 236.2 0.0 5.1e-70 235.9 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 CRK14216.1 - 5.5e-07 29.8 0.0 8.2e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 CRK14216.1 - 0.081 11.8 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) ADH_N PF08240.12 CRK14217.1 - 2.2e-28 98.3 0.1 3.8e-28 97.5 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CRK14217.1 - 6.6e-23 81.1 0.1 1.1e-22 80.4 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CRK14217.1 - 0.0021 19.1 0.0 0.0033 18.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 CRK14217.1 - 0.13 11.6 0.4 0.3 10.4 0.1 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.21 CRK14217.1 - 0.2 11.0 1.0 0.34 10.2 1.0 1.3 1 0 0 1 1 1 0 ThiF family Tfb4 PF03850.14 CRK14219.1 - 2.2e-83 279.9 7.6 9e-47 159.9 0.9 2.0 1 1 1 2 2 2 2 Transcription factor Tfb4 UNC45-central PF11701.8 CRK14220.1 - 1.5e-55 187.4 1.3 4.7e-52 176.0 0.0 3.7 3 0 0 3 3 3 2 Myosin-binding striated muscle assembly central HEAT_2 PF13646.6 CRK14220.1 - 0.0026 18.1 16.8 0.025 14.9 2.3 5.7 4 2 1 5 5 5 1 HEAT repeats HEAT_EZ PF13513.6 CRK14220.1 - 0.025 15.1 4.5 11 6.6 0.0 5.1 5 0 0 5 5 5 0 HEAT-like repeat Vac14_Fab1_bd PF12755.7 CRK14220.1 - 0.035 14.7 0.0 0.13 12.9 0.0 2.0 1 0 0 1 1 1 0 Vacuolar 14 Fab1-binding region HEAT PF02985.22 CRK14220.1 - 0.18 12.1 11.0 3.1 8.3 0.0 5.8 6 0 0 6 6 6 0 HEAT repeat DUF4259 PF14078.6 CRK14220.1 - 3.3 8.4 4.7 74 4.1 0.0 3.9 3 1 1 4 4 4 0 Domain of unknown function (DUF4259) tRNA_U5-meth_tr PF05958.11 CRK14221.1 - 3.5e-11 42.7 0.0 6.7e-10 38.5 0.0 2.4 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_15 PF09445.10 CRK14221.1 - 6.9e-06 25.7 0.0 1.2e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_31 PF13847.6 CRK14221.1 - 0.00058 19.7 0.0 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK14221.1 - 0.0084 16.8 0.0 0.018 15.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltrans_SAM PF10672.9 CRK14221.1 - 0.013 14.6 0.0 0.021 14.0 0.0 1.2 1 0 0 1 1 1 0 S-adenosylmethionine-dependent methyltransferase PrmA PF06325.13 CRK14221.1 - 0.055 12.9 0.0 0.097 12.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.15 CRK14221.1 - 0.17 11.5 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 G_glu_transpept PF01019.21 CRK14222.1 - 2.4e-145 485.2 2.2 1.6e-106 357.1 0.6 2.0 1 1 1 2 2 2 2 Gamma-glutamyltranspeptidase DUF4981 PF16353.5 CRK14222.1 - 0.089 13.3 0.1 0.21 12.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function(DUF4981) ALG11_N PF15924.5 CRK14223.1 - 1.3e-79 267.1 0.3 1.3e-78 263.9 0.0 2.1 2 0 0 2 2 2 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 CRK14223.1 - 1.3e-20 73.7 0.0 2.3e-20 72.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CRK14223.1 - 7.2e-10 39.4 0.1 1.8e-09 38.1 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CRK14223.1 - 0.0013 18.8 0.0 0.002 18.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 60KD_IMP PF02096.20 CRK14224.1 - 0.00024 21.1 0.0 0.0003 20.7 0.0 1.3 1 1 0 1 1 1 1 60Kd inner membrane protein FA_desaturase PF00487.24 CRK14224.1 - 2.1 8.1 9.0 0.27 11.0 0.4 2.6 2 1 1 3 3 3 0 Fatty acid desaturase Syntaxin_2 PF14523.6 CRK14225.1 - 5.2e-25 87.8 4.0 5.2e-25 87.8 4.0 2.4 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 CRK14225.1 - 1.8e-14 53.4 1.2 1.8e-14 53.4 1.2 2.0 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 CRK14225.1 - 0.0026 17.4 12.8 0.0068 16.1 12.8 1.7 1 1 0 1 1 1 1 Syntaxin FapA PF03961.13 CRK14225.1 - 0.01 14.5 1.1 0.01 14.5 1.1 1.8 1 1 1 2 2 2 0 Flagellar Assembly Protein A DUF883 PF05957.13 CRK14225.1 - 0.024 15.2 11.6 0.058 14.0 0.1 3.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) K_channel_TID PF07941.11 CRK14225.1 - 0.073 13.5 1.5 0.18 12.3 1.5 1.6 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Nre_C PF04895.12 CRK14225.1 - 0.11 12.4 0.1 0.37 10.7 0.1 1.8 1 0 0 1 1 1 0 Archaeal Nre, C-terminal DUF1664 PF07889.12 CRK14225.1 - 0.24 11.5 10.1 3.4 7.7 0.5 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Syntaxin-6_N PF09177.11 CRK14225.1 - 0.31 11.6 0.1 0.31 11.6 0.1 3.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Hamartin PF04388.12 CRK14225.1 - 0.57 8.8 6.0 0.61 8.7 6.0 1.1 1 0 0 1 1 1 0 Hamartin protein PAH PF02671.21 CRK14225.1 - 0.68 10.1 0.1 0.68 10.1 0.1 2.5 2 1 0 2 2 1 0 Paired amphipathic helix repeat DUF4635 PF15466.6 CRK14225.1 - 0.91 9.0 8.6 2.9 7.4 0.3 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4635) T3SSipB PF16535.5 CRK14225.1 - 1.2 9.6 11.8 0.57 10.6 7.6 2.4 2 1 0 2 2 2 0 Type III cell invasion protein SipB Med15 PF09606.10 CRK14225.1 - 1.3 7.6 8.4 1.7 7.2 8.4 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal NICE-3 PF07406.11 CRK14226.1 - 0.00088 19.3 0.5 0.004 17.2 0.1 2.1 2 0 0 2 2 2 1 NICE-3 protein DUF4129 PF13559.6 CRK14226.1 - 0.026 14.8 0.0 0.059 13.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4129) HET PF06985.11 CRK14227.1 - 0.0018 18.6 0.0 0.002 18.5 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase PF00069.25 CRK14228.1 - 2.3e-20 73.1 0.0 1.1e-16 61.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CRK14228.1 - 3.2e-06 26.6 0.0 0.00084 18.7 0.0 2.8 3 0 0 3 3 3 2 Protein tyrosine kinase Git3 PF11710.8 CRK14229.1 - 2.4e-10 40.5 6.6 1.1e-09 38.4 6.6 1.9 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Dicty_CAR PF05462.11 CRK14229.1 - 2.8e-05 23.4 4.5 0.00025 20.3 2.4 2.1 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor GPR_Gpa2_C PF11970.8 CRK14229.1 - 0.00014 21.9 0.2 0.0009 19.3 0.0 2.3 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.21 CRK14229.1 - 0.004 16.5 0.2 0.0052 16.1 0.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF3270 PF11674.8 CRK14229.1 - 0.13 12.5 0.2 0.28 11.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3270) Orexin PF02072.15 CRK14229.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Prepro-orexin tRNA-synt_2c PF01411.19 CRK14230.1 - 1.1e-12 47.2 0.0 1.6e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 CRK14230.1 - 2.5e-05 24.3 0.1 4.9e-05 23.4 0.1 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TauD PF02668.16 CRK14231.1 - 1.5e-33 116.7 0.1 2.2e-33 116.2 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Vps16_C PF04840.12 CRK14232.1 - 1.8e-85 286.8 0.0 2.6e-85 286.3 0.0 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region Vps16_N PF04841.13 CRK14232.1 - 2e-80 270.5 0.0 2.9e-80 270.0 0.0 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region DOT1 PF08123.13 CRK14232.1 - 1.8e-64 217.0 0.1 3e-64 216.3 0.1 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 FHA PF00498.26 CRK14232.1 - 2.9e-14 53.1 0.0 6.5e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 CRK14232.1 - 3.2e-13 49.1 5.9 6.7e-13 48.1 5.9 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 CRK14232.1 - 9.1e-07 29.1 9.2 1.7e-06 28.2 9.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CRK14232.1 - 0.0042 16.9 9.3 0.008 16.0 9.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CRK14232.1 - 0.0069 16.3 6.9 0.013 15.4 6.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 CRK14232.1 - 0.011 16.0 6.2 0.025 14.9 6.2 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain ANAPC4_WD40 PF12894.7 CRK14232.1 - 0.017 15.4 0.0 0.31 11.4 0.0 2.8 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Yop-YscD_cpl PF16697.5 CRK14232.1 - 0.042 14.2 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain PHD PF00628.29 CRK14232.1 - 0.051 13.5 5.2 0.095 12.6 5.2 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING_UBOX PF13445.6 CRK14232.1 - 0.055 13.5 8.3 0.13 12.3 8.3 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CRK14232.1 - 0.06 13.2 8.7 0.12 12.2 8.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CRK14232.1 - 0.12 12.4 2.4 0.28 11.3 2.4 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger ATG16 PF08614.11 CRK14233.1 - 1.2e-54 185.6 21.0 1.4e-54 185.4 21.0 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF4201 PF13870.6 CRK14233.1 - 0.00083 19.1 16.3 0.0036 17.0 13.4 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF4201) Golgin_A5 PF09787.9 CRK14233.1 - 0.045 13.2 12.3 0.057 12.9 12.3 1.2 1 1 0 1 1 1 0 Golgin subfamily A member 5 YkyA PF10368.9 CRK14233.1 - 0.097 12.3 15.2 0.12 12.0 12.7 1.9 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein ASD2 PF08687.11 CRK14233.1 - 0.11 12.1 0.1 0.11 12.1 0.1 2.7 1 1 2 3 3 3 0 Apx/Shroom domain ASD2 Spc7 PF08317.11 CRK14233.1 - 0.24 10.3 15.1 0.15 11.0 11.4 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein Atg14 PF10186.9 CRK14233.1 - 0.67 9.0 11.7 1.1 8.3 11.7 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 UPF0242 PF06785.11 CRK14233.1 - 0.68 10.0 15.0 3 7.9 15.0 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus APG6_N PF17675.1 CRK14233.1 - 1.6 9.3 24.9 15 6.1 9.6 2.7 1 1 1 2 2 2 0 Apg6 coiled-coil region BRE1 PF08647.11 CRK14233.1 - 1.7 8.8 18.5 1.1 9.4 13.9 2.5 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase SlyX PF04102.12 CRK14233.1 - 2.4 8.8 16.6 3.3 8.4 1.6 3.2 2 1 1 3 3 3 0 SlyX Ribonuc_red_lgN PF00317.21 CRK14233.1 - 4.9 7.2 6.1 30 4.7 6.1 2.1 1 1 0 1 1 1 0 Ribonucleotide reductase, all-alpha domain FlxA PF14282.6 CRK14233.1 - 8 6.5 8.7 1e+02 3.0 8.7 2.4 1 1 0 1 1 1 0 FlxA-like protein S1 PF00575.23 CRK14236.1 - 1.7e-75 249.4 46.2 8.4e-14 51.7 0.3 13.5 13 0 0 13 13 13 11 S1 RNA binding domain TPR_19 PF14559.6 CRK14236.1 - 6.4e-07 29.8 4.0 0.19 12.3 0.0 4.5 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 CRK14236.1 - 0.0001 22.8 3.6 14 6.8 0.0 5.4 2 1 3 5 5 5 1 Tetratricopeptide repeat RNase_II_C_S1 PF18614.1 CRK14236.1 - 0.0015 18.4 12.6 7.2 6.6 0.5 7.0 6 1 0 6 6 6 1 RNase II-type exonuclease C-terminal S1 domain NRDE-2 PF08424.10 CRK14236.1 - 0.0038 16.4 2.2 0.16 11.1 0.2 3.0 1 1 2 3 3 3 2 NRDE-2, necessary for RNA interference TPR_17 PF13431.6 CRK14236.1 - 0.018 15.4 0.4 1.2 9.7 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat S1_2 PF13509.6 CRK14236.1 - 0.022 14.8 0.2 52 4.0 0.0 5.3 4 0 0 4 4 4 0 S1 domain TPR_16 PF13432.6 CRK14236.1 - 0.04 14.6 2.2 12 6.7 0.0 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 CRK14236.1 - 0.085 13.5 1.2 52 4.8 0.0 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat BPL_C PF02237.17 CRK14236.1 - 0.1 12.5 3.1 4.8 7.2 0.0 4.1 4 0 0 4 4 4 0 Biotin protein ligase C terminal domain PilZ PF07238.14 CRK14236.1 - 0.11 12.8 0.2 2.8 8.3 0.0 3.5 2 1 1 3 3 3 0 PilZ domain TPR_12 PF13424.6 CRK14236.1 - 0.13 12.6 1.7 19 5.7 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Myosin_N PF02736.19 CRK14236.1 - 6.8 6.6 6.3 13 5.7 0.1 4.1 4 0 0 4 4 4 0 Myosin N-terminal SH3-like domain AGTRAP PF06396.11 CRK14239.1 - 0.34 10.7 3.3 0.99 9.2 0.9 2.3 1 1 1 2 2 2 0 Angiotensin II, type I receptor-associated protein (AGTRAP) S1 PF00575.23 CRK14240.1 - 3e-30 104.4 11.9 2.4e-14 53.4 0.3 3.4 3 0 0 3 3 3 3 S1 RNA binding domain TPR_19 PF14559.6 CRK14240.1 - 1.4e-07 31.9 6.4 0.33 11.5 0.0 4.4 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 CRK14240.1 - 4.2e-07 30.3 5.6 4.8 8.3 0.0 6.0 3 1 3 6 6 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 CRK14240.1 - 0.00043 20.5 0.6 0.28 11.7 0.1 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat NRDE-2 PF08424.10 CRK14240.1 - 0.00045 19.4 2.5 0.031 13.4 0.3 3.2 1 1 2 3 3 3 1 NRDE-2, necessary for RNA interference TPR_6 PF13174.6 CRK14240.1 - 0.0017 18.9 1.3 18 6.3 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 CRK14240.1 - 0.0061 16.8 2.3 4.8 7.6 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat Nop14 PF04147.12 CRK14240.1 - 0.036 12.3 14.8 0.051 11.8 14.8 1.1 1 0 0 1 1 1 0 Nop14-like family TPR_10 PF13374.6 CRK14240.1 - 0.089 12.7 0.9 10 6.2 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 CRK14240.1 - 0.14 12.3 3.1 0.45 10.8 0.0 3.5 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 CRK14240.1 - 0.15 12.4 0.1 2.7 8.4 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat SDA1 PF05285.12 CRK14240.1 - 0.15 11.4 14.8 0.25 10.7 14.8 1.4 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 CRK14240.1 - 0.46 8.7 10.4 0.73 8.1 10.4 1.2 1 0 0 1 1 1 0 CDC45-like protein TPR_16 PF13432.6 CRK14240.1 - 1.1 10.0 15.2 1.8 9.3 0.2 4.9 5 1 1 6 6 4 0 Tetratricopeptide repeat BUD22 PF09073.10 CRK14240.1 - 3 7.1 19.0 5.5 6.2 19.0 1.3 1 0 0 1 1 1 0 BUD22 FAD_binding_4 PF01565.23 CRK14242.1 - 2.3e-22 79.2 4.1 3.4e-22 78.7 4.1 1.2 1 0 0 1 1 1 1 FAD binding domain Glyco_hydro_43 PF04616.14 CRK14243.1 - 1.6e-06 27.7 0.0 2.3e-06 27.1 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 NTP_transferase PF00483.23 CRK14244.1 - 0.095 12.3 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Nucleotidyl transferase Glyco_hydro_43 PF04616.14 CRK14245.1 - 4e-24 85.4 0.0 5.4e-24 85.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 CBM_35 PF16990.5 CRK14246.1 - 0.11 12.7 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate binding module (family 35) peroxidase PF00141.23 CRK14247.1 - 1.5e-24 86.9 0.0 2.5e-24 86.2 0.0 1.3 1 0 0 1 1 1 1 Peroxidase DUF3094 PF11293.8 CRK14247.1 - 0.19 11.5 0.0 0.36 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3094) Ceramidase PF05875.12 CRK14248.1 - 4.4e-58 196.8 5.1 5.2e-58 196.5 5.1 1.0 1 0 0 1 1 1 1 Ceramidase MFS_1 PF07690.16 CRK14249.1 - 3.3e-25 88.8 48.8 1.5e-20 73.4 28.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PIF1 PF05970.14 CRK14250.1 - 1.5e-57 195.5 0.1 7.1e-55 186.6 0.1 2.2 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 CRK14250.1 - 4.6e-19 68.9 0.0 7.9e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CRK14250.1 - 6e-10 39.6 0.0 1.2e-09 38.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CRK14250.1 - 2.4e-06 27.8 0.0 6.5e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 CRK14250.1 - 0.00016 22.1 0.0 0.00045 20.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 CRK14250.1 - 0.00017 21.2 0.0 0.00034 20.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 CRK14250.1 - 0.00021 21.7 0.0 0.00048 20.6 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Herpes_Helicase PF02689.14 CRK14250.1 - 0.0003 18.9 0.1 0.00082 17.4 0.0 1.6 2 0 0 2 2 2 1 Helicase UvrD_C_2 PF13538.6 CRK14250.1 - 0.00058 19.6 0.0 0.0014 18.5 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_5 PF07728.14 CRK14250.1 - 0.0042 17.1 0.1 0.018 15.0 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 CRK14250.1 - 0.0054 17.3 0.0 0.023 15.2 0.0 2.0 2 0 0 2 2 2 1 ABC transporter PhoH PF02562.16 CRK14250.1 - 0.0091 15.5 0.1 0.031 13.7 0.0 1.9 2 0 0 2 2 2 1 PhoH-like protein RNA_helicase PF00910.22 CRK14250.1 - 0.011 16.1 0.0 0.028 14.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.22 CRK14250.1 - 0.014 14.6 0.1 0.025 13.8 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF2075 PF09848.9 CRK14250.1 - 0.021 14.1 0.0 0.036 13.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 CRK14250.1 - 0.032 14.1 0.0 0.065 13.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain T2SSE PF00437.20 CRK14250.1 - 0.033 13.2 0.0 0.055 12.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein IstB_IS21 PF01695.17 CRK14250.1 - 0.039 13.7 0.0 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF815 PF05673.13 CRK14250.1 - 0.074 12.2 0.1 0.21 10.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_11 PF13086.6 CRK14250.1 - 0.1 12.4 0.5 0.35 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 CRK14250.1 - 0.1 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase_2 PF01637.18 CRK14250.1 - 0.12 12.3 0.0 0.32 10.9 0.0 1.8 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea SH3_13 PF18335.1 CRK14250.1 - 0.12 12.2 0.0 0.43 10.5 0.0 1.9 2 0 0 2 2 1 0 ATP-dependent RecD-like DNA helicase SH3 domain RsgA_GTPase PF03193.16 CRK14250.1 - 0.13 12.2 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase YjeF_N PF03853.15 CRK14251.1 - 3.8e-41 140.8 0.3 5.4e-41 140.3 0.3 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.10 CRK14251.1 - 1e-08 36.0 2.0 3.8e-08 34.1 2.0 2.0 1 0 0 1 1 1 1 FDF domain AAA PF00004.29 CRK14252.1 - 2.7e-98 325.5 0.0 1.1e-47 161.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CRK14252.1 - 2.3e-24 84.9 3.3 7.4e-13 48.1 0.3 3.3 2 1 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 CRK14252.1 - 5.7e-19 68.1 0.4 2.2e-18 66.2 0.4 2.1 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 CRK14252.1 - 7.3e-15 55.1 0.1 3.2e-06 27.0 0.0 3.6 4 1 0 4 4 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 CRK14252.1 - 8.2e-14 52.1 0.0 2.1e-07 31.2 0.0 2.9 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 CRK14252.1 - 2e-13 51.1 0.0 0.00019 21.9 0.0 4.3 2 2 1 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 CRK14252.1 - 5.1e-12 46.0 0.4 3.4e-06 27.1 0.1 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 CRK14252.1 - 7.2e-12 45.7 0.0 4.6e-05 23.6 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.6 CRK14252.1 - 1.6e-09 38.2 0.4 0.028 14.7 0.0 4.1 2 2 2 4 4 4 2 AAA domain TIP49 PF06068.13 CRK14252.1 - 2.8e-09 36.6 0.0 0.0011 18.2 0.0 2.8 2 0 0 2 2 2 2 TIP49 P-loop domain CDC48_2 PF02933.17 CRK14252.1 - 1.9e-07 30.8 0.0 4.3e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_18 PF13238.6 CRK14252.1 - 1.9e-07 31.7 0.0 0.028 15.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 CRK14252.1 - 2.1e-07 30.7 4.3 0.29 10.7 0.1 4.9 3 2 1 5 5 5 3 AAA domain Mg_chelatase PF01078.21 CRK14252.1 - 2.8e-07 30.2 0.4 0.0084 15.5 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 CRK14252.1 - 3.1e-07 30.3 0.0 0.019 14.7 0.0 2.8 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.6 CRK14252.1 - 3.7e-07 30.2 0.0 0.0081 16.2 0.0 2.9 3 0 0 3 3 2 2 AAA domain ATPase PF06745.13 CRK14252.1 - 5.7e-07 29.1 0.3 0.25 10.7 0.0 3.6 3 0 0 3 3 3 2 KaiC RNA_helicase PF00910.22 CRK14252.1 - 5.8e-07 29.9 0.0 0.031 14.7 0.0 2.8 3 0 0 3 3 2 2 RNA helicase AAA_7 PF12775.7 CRK14252.1 - 1.2e-06 28.2 0.0 0.021 14.3 0.0 2.9 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_24 PF13479.6 CRK14252.1 - 4.5e-06 26.5 0.0 0.083 12.6 0.0 2.8 3 0 0 3 3 2 2 AAA domain Parvo_NS1 PF01057.17 CRK14252.1 - 8.8e-06 25.0 0.0 0.051 12.7 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 DUF815 PF05673.13 CRK14252.1 - 1.3e-05 24.5 0.0 0.046 12.9 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF815) Bac_DnaA PF00308.18 CRK14252.1 - 1.5e-05 24.9 0.0 0.12 12.2 0.0 3.3 3 0 0 3 3 3 2 Bacterial dnaA protein AAA_28 PF13521.6 CRK14252.1 - 1.8e-05 25.0 0.0 0.18 12.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 CRK14252.1 - 2.3e-05 24.2 0.1 0.23 11.1 0.0 3.3 2 2 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.27 CRK14252.1 - 3.1e-05 24.5 0.0 0.35 11.4 0.0 3.4 2 1 0 2 2 2 2 ABC transporter TsaE PF02367.17 CRK14252.1 - 7.7e-05 22.7 0.0 0.52 10.3 0.0 2.7 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Vps4_C PF09336.10 CRK14252.1 - 8e-05 22.6 1.0 0.00068 19.6 0.1 2.8 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain AAA_3 PF07726.11 CRK14252.1 - 0.00014 21.8 0.2 0.68 9.8 0.0 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 CRK14252.1 - 0.00015 21.8 0.1 0.18 11.7 0.0 2.8 3 0 0 3 3 3 1 NACHT domain ResIII PF04851.15 CRK14252.1 - 0.00019 21.5 0.0 0.046 13.7 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_17 PF13207.6 CRK14252.1 - 0.00021 21.7 0.0 0.59 10.5 0.0 3.0 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 CRK14252.1 - 0.00023 20.7 0.3 0.7 9.3 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA_30 PF13604.6 CRK14252.1 - 0.00039 20.2 0.2 0.98 9.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.6 CRK14252.1 - 0.00043 20.1 0.0 1.3 8.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 CRK14252.1 - 0.00054 19.9 0.0 1.9 8.4 0.0 3.6 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_19 PF13245.6 CRK14252.1 - 0.0017 18.7 0.9 5.9 7.2 0.0 3.5 3 1 1 4 4 3 0 AAA domain DUF2075 PF09848.9 CRK14252.1 - 0.0019 17.5 0.0 1.6 7.9 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Sigma54_activ_2 PF14532.6 CRK14252.1 - 0.0037 17.4 0.0 0.51 10.5 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain NTPase_1 PF03266.15 CRK14252.1 - 0.0052 16.7 0.5 2.5 8.0 0.0 3.8 4 0 0 4 4 3 1 NTPase NB-ARC PF00931.22 CRK14252.1 - 0.0054 16.0 0.0 1.7 7.7 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain Viral_helicase1 PF01443.18 CRK14252.1 - 0.0068 16.2 0.0 0.34 10.6 0.0 2.5 3 0 0 3 3 2 1 Viral (Superfamily 1) RNA helicase KAP_NTPase PF07693.14 CRK14252.1 - 0.0087 15.3 0.4 0.86 8.8 0.0 3.3 2 2 1 4 4 4 1 KAP family P-loop domain IPT PF01745.16 CRK14252.1 - 0.011 15.1 0.0 1.8 7.9 0.0 2.4 2 0 0 2 2 2 0 Isopentenyl transferase Zeta_toxin PF06414.12 CRK14252.1 - 0.024 13.9 0.4 8 5.7 0.0 2.8 3 0 0 3 3 2 0 Zeta toxin UFD1 PF03152.14 CRK14252.1 - 0.027 14.0 0.0 0.21 11.0 0.0 2.0 1 1 1 2 2 2 0 Ubiquitin fusion degradation protein UFD1 Cytidylate_kin PF02224.18 CRK14252.1 - 0.04 13.7 0.7 10 5.8 0.0 3.2 3 0 0 3 3 3 0 Cytidylate kinase AAA_6 PF12774.7 CRK14252.1 - 0.044 12.8 0.2 7.6 5.4 0.0 2.5 3 0 0 3 3 2 0 Hydrolytic ATP binding site of dynein motor region Zot PF05707.12 CRK14252.1 - 0.056 13.1 0.0 2.4 7.8 0.0 2.9 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) AFG1_ATPase PF03969.16 CRK14252.1 - 0.11 11.4 0.0 13 4.6 0.0 2.2 2 0 0 2 2 2 0 AFG1-like ATPase EnY2 PF10163.9 CRK14253.1 - 0.00021 21.6 0.0 0.0027 18.0 0.0 2.0 2 0 0 2 2 2 1 Transcription factor e(y)2 ERAP1_C PF11838.8 CRK14253.1 - 0.059 12.9 0.1 0.071 12.6 0.1 1.1 1 0 0 1 1 1 0 ERAP1-like C-terminal domain Ribosomal_60s PF00428.19 CRK14254.1 - 0.0048 17.5 4.2 0.0056 17.2 4.2 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein NOA36 PF06524.12 CRK14254.1 - 0.033 13.5 6.6 0.034 13.5 6.6 1.0 1 0 0 1 1 1 0 NOA36 protein ANAPC15 PF15243.6 CRK14254.1 - 0.042 14.3 4.1 0.049 14.0 4.1 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 Cwf_Cwc_15 PF04889.12 CRK14254.1 - 0.17 11.6 7.6 0.19 11.4 7.6 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Pinin_SDK_N PF04697.13 CRK14254.1 - 0.24 12.1 4.7 0.28 11.8 4.7 1.1 1 0 0 1 1 1 0 pinin/SDK conserved region RXT2_N PF08595.11 CRK14254.1 - 0.32 11.0 2.1 0.37 10.8 2.1 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal PGA2 PF07543.12 CRK14254.1 - 0.33 10.9 2.7 0.42 10.6 2.7 1.1 1 0 0 1 1 1 0 Protein trafficking PGA2 RNA_pol_3_Rpc31 PF11705.8 CRK14254.1 - 0.35 11.1 10.7 0.36 11.0 10.7 1.0 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CENP-B_dimeris PF09026.10 CRK14254.1 - 0.37 11.2 10.4 0.57 10.6 10.4 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 CRK14254.1 - 2.2 6.3 7.8 2 6.4 7.8 1.0 1 0 0 1 1 1 0 DNA polymerase phi Astro_capsid_p PF12226.8 CRK14254.1 - 2.3 7.3 6.0 2.5 7.2 6.0 1.0 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DUF3984 PF13136.6 CRK14258.1 - 6.5e-41 140.8 16.2 8.3e-41 140.5 16.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3984) IKI3 PF04762.12 CRK14259.1 - 1.2e-151 506.7 0.0 1.4e-151 506.5 0.0 1.0 1 0 0 1 1 1 1 IKI3 family ANAPC4_WD40 PF12894.7 CRK14259.1 - 2.3e-06 27.8 0.9 4.5 7.6 0.0 5.2 4 1 1 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Ras PF00071.22 CRK14260.1 - 1.6e-51 174.1 0.0 8.5e-46 155.5 0.0 2.0 2 0 0 2 2 2 2 Ras family Roc PF08477.13 CRK14260.1 - 3.7e-18 65.9 0.0 1.1e-13 51.5 0.0 2.2 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase baeRF_family3 PF18845.1 CRK14260.1 - 0.17 12.2 0.0 0.57 10.4 0.0 1.7 1 1 1 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 3 NB-ARC PF00931.22 CRK14260.1 - 0.17 11.0 0.1 1.8 7.7 0.0 2.0 1 1 1 2 2 2 0 NB-ARC domain Skp1 PF01466.19 CRK14260.1 - 0.32 11.1 1.1 1.1 9.4 0.2 2.3 3 0 0 3 3 3 0 Skp1 family, dimerisation domain Zn_clus PF00172.18 CRK14262.1 - 2e-05 24.6 8.0 2.8e-05 24.1 8.0 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lar_restr_allev PF14354.6 CRK14262.1 - 0.059 13.7 3.1 0.089 13.2 3.1 1.3 1 0 0 1 1 1 0 Restriction alleviation protein Lar CT_A_B PF02626.15 CRK14263.1 - 2.4e-89 299.5 0.0 3.6e-89 298.9 0.0 1.3 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain A and B CPSase_L_D2 PF02786.17 CRK14263.1 - 5e-64 215.7 0.3 8.9e-64 214.9 0.3 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 CRK14263.1 - 7.7e-40 135.9 0.5 4.1e-39 133.5 0.1 2.2 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 CRK14263.1 - 2.3e-33 114.5 0.0 6.5e-33 113.1 0.0 1.9 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CT_C_D PF02682.16 CRK14263.1 - 4.5e-31 108.2 0.0 1.1e-30 106.9 0.0 1.6 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D Amidase PF01425.21 CRK14263.1 - 1.1e-13 51.0 0.0 1.7e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Amidase Dala_Dala_lig_C PF07478.13 CRK14263.1 - 5.7e-12 45.6 0.0 1.1e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 CRK14263.1 - 0.00025 20.6 0.1 0.00049 19.7 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 CRK14263.1 - 0.00051 20.1 0.0 0.001 19.1 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.6 CRK14263.1 - 0.011 15.5 0.1 0.023 14.4 0.1 1.5 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon zf-CCCH_4 PF18044.1 CRK14264.1 - 2.5e-07 30.3 2.4 2.5e-07 30.3 2.4 1.6 2 0 0 2 2 2 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CRK14264.1 - 3e-07 30.3 5.9 6e-07 29.3 5.9 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 CRK14264.1 - 7e-06 25.8 2.5 1.2e-05 25.0 2.5 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 CRK14264.1 - 0.00033 20.8 1.3 0.00041 20.5 0.2 1.7 2 0 0 2 2 2 1 Zinc-finger containing family Torus PF16131.5 CRK14264.1 - 0.0047 17.6 0.2 0.0047 17.6 0.2 2.0 3 0 0 3 3 3 1 Torus domain zf-CCCH_2 PF14608.6 CRK14264.1 - 0.0048 17.3 1.4 0.0075 16.7 1.4 1.3 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger Tegument_dsDNA PF12818.7 CRK14264.1 - 0.63 9.1 2.7 0.85 8.7 2.7 1.2 1 0 0 1 1 1 0 dsDNA viral tegument protein TFIIA PF03153.13 CRK14264.1 - 3.9 7.4 12.8 4.6 7.1 12.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Glyco_hydro_7 PF00840.20 CRK14272.1 - 1.2e-119 400.0 17.1 1.3e-119 399.8 17.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 C2 PF00168.30 CRK14288.1 - 2.5e-82 271.8 0.5 2.5e-22 79.1 0.0 5.5 5 0 0 5 5 5 5 C2 domain SMP_LBD PF17047.5 CRK14288.1 - 0.0003 20.3 0.0 0.00063 19.3 0.0 1.6 1 1 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain DUF908 PF06012.12 CRK14288.1 - 0.011 15.1 0.7 0.025 14.0 0.7 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) FKBP_C PF00254.28 CRK14288.1 - 0.03 14.6 0.0 0.093 13.1 0.0 1.8 1 0 0 1 1 1 0 FKBP-type peptidyl-prolyl cis-trans isomerase NT-C2 PF10358.9 CRK14288.1 - 0.11 12.2 3.6 0.57 9.9 0.2 3.4 3 1 0 3 3 3 0 N-terminal C2 in EEIG1 and EHBP1 proteins Sec3_C PF09763.9 CRK14304.1 - 2.7e-192 640.9 5.8 3.5e-192 640.5 5.8 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3_C_2 PF15278.6 CRK14304.1 - 0.0019 18.5 0.2 0.009 16.3 0.0 2.2 2 0 0 2 2 2 1 Sec3 exocyst complex subunit Vps52 PF04129.12 CRK14304.1 - 0.017 13.9 1.5 0.075 11.8 0.0 2.3 3 0 0 3 3 3 0 Vps52 / Sac2 family Aminotran_1_2 PF00155.21 CRK14306.1 - 5.2e-40 137.7 0.0 6.3e-40 137.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Usp PF00582.26 CRK14307.1 - 4.3e-40 137.5 15.4 1.4e-15 58.1 0.5 4.8 5 0 0 5 5 5 4 Universal stress protein family RNase_PH PF01138.21 CRK14307.1 - 0.0022 18.5 0.8 11 6.5 0.0 4.1 1 1 2 3 3 3 2 3' exoribonuclease family, domain 1 PIN_2 PF10130.9 CRK14307.1 - 0.0065 16.7 1.6 4.2 7.6 0.1 2.5 2 0 0 2 2 2 2 PIN domain EccE PF11203.8 CRK14307.1 - 0.0092 16.3 2.9 4.2 7.8 0.2 2.9 2 0 0 2 2 2 2 Putative type VII ESX secretion system translocon, EccE baeRF_family2 PF18844.1 CRK14307.1 - 0.011 15.8 3.3 3.1 7.9 0.2 2.6 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 2 DASH_Dad1 PF08649.10 CRK14307.1 - 8.8 6.6 5.3 53 4.1 0.5 2.5 2 0 0 2 2 2 0 DASH complex subunit Dad1 DUF1556 PF07590.11 CRK14309.1 - 0.23 11.8 0.1 0.23 11.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1556) DUF5473 PF17567.2 CRK14312.1 - 0.078 13.3 3.0 0.13 12.6 3.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5473) Glyco_hydro_45 PF02015.16 CRK14313.1 - 1.1e-85 286.8 16.0 1.4e-85 286.5 16.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 NB-ARC PF00931.22 CRK14315.1 - 9.2e-08 31.6 0.0 2.8e-07 30.0 0.0 1.7 1 1 0 1 1 1 1 NB-ARC domain NACHT PF05729.12 CRK14315.1 - 9e-05 22.4 0.0 0.00019 21.4 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Helo_like_N PF17111.5 CRK14315.1 - 0.00021 20.7 0.1 0.00038 19.9 0.1 1.4 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins AAA_22 PF13401.6 CRK14315.1 - 0.0018 18.5 0.0 0.0098 16.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 CRK14315.1 - 0.0052 16.5 0.0 0.05 13.3 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein KH_dom-like PF14714.6 CRK14315.1 - 0.069 13.5 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal Fzo_mitofusin PF04799.13 CRK14315.1 - 0.089 12.3 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 fzo-like conserved region Asp PF00026.23 CRK14316.1 - 3.4e-57 194.2 0.0 4.2e-57 193.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CRK14316.1 - 5.8e-09 36.4 1.9 0.00028 21.2 0.0 2.5 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal His_Phos_1 PF00300.22 CRK14317.1 - 1.4e-10 41.2 0.3 3.7e-10 39.8 0.1 1.8 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) SET PF00856.28 CRK14317.1 - 3.2e-10 40.7 0.0 2.4e-09 37.8 0.0 2.2 1 1 0 1 1 1 1 SET domain SGL PF08450.12 CRK14318.1 - 4.7e-05 23.1 0.0 9.1e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 CRK14318.1 - 0.013 15.7 0.0 0.025 14.8 0.0 1.5 1 0 0 1 1 1 0 Arylesterase NHL PF01436.21 CRK14318.1 - 0.033 14.2 0.9 6.2 7.1 0.0 3.3 3 0 0 3 3 3 0 NHL repeat Acetyltransf_1 PF00583.25 CRK14320.1 - 1.8e-14 54.0 0.0 2.3e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CRK14320.1 - 6.7e-07 29.3 0.0 1e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CRK14320.1 - 7.1e-06 26.4 0.0 1.1e-05 25.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CRK14320.1 - 7.1e-06 25.9 0.0 1.3e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 CRK14320.1 - 0.002 18.8 0.0 0.0027 18.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CRK14320.1 - 0.045 13.9 0.0 0.091 12.9 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase HAD_2 PF13419.6 CRK14321.1 - 1.5e-10 41.5 0.0 2.7e-10 40.6 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CRK14321.1 - 0.00022 21.6 0.0 0.00051 20.4 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase TPR_12 PF13424.6 CRK14322.1 - 1.8e-17 63.4 11.4 1.2e-06 28.7 0.0 4.1 1 1 3 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.6 CRK14322.1 - 1.9e-16 59.3 8.5 0.00028 20.6 0.1 5.2 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_MalT PF17874.1 CRK14322.1 - 3.7e-12 46.3 5.8 1.3e-06 28.1 0.8 2.1 1 1 1 2 2 2 2 MalT-like TPR region TPR_2 PF07719.17 CRK14322.1 - 1e-08 34.6 7.5 0.069 13.3 0.2 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 CRK14322.1 - 2.6e-08 33.3 11.5 0.25 11.4 0.0 5.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 CRK14322.1 - 3.8e-08 33.7 5.2 0.064 13.8 0.0 5.0 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_4 PF07721.14 CRK14322.1 - 4.7e-08 32.9 4.2 0.12 13.1 0.0 4.4 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 CRK14322.1 - 1.7e-06 28.6 3.4 0.45 11.2 0.1 4.8 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 CRK14322.1 - 4.6e-05 23.9 7.2 0.77 10.7 0.1 5.4 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 CRK14322.1 - 5.8e-05 22.7 0.7 3.2 7.7 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 CRK14322.1 - 0.00065 19.9 0.1 16 6.1 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 CRK14322.1 - 0.007 16.5 3.8 7.7 7.0 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat Dopey_N PF04118.14 CRK14322.1 - 0.042 13.0 0.0 0.061 12.4 0.0 1.2 1 0 0 1 1 1 0 Dopey, N-terminal PPR PF01535.20 CRK14322.1 - 0.061 13.6 0.0 36 4.9 0.0 3.7 4 0 0 4 4 4 0 PPR repeat NB-ARC PF00931.22 CRK14323.1 - 2.2e-09 36.9 0.0 0.00017 20.9 0.0 2.2 2 0 0 2 2 2 2 NB-ARC domain IstB_IS21 PF01695.17 CRK14323.1 - 0.028 14.1 0.0 0.11 12.2 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein RGS PF00615.19 CRK14324.1 - 0.023 14.9 0.0 0.052 13.8 0.0 1.5 2 0 0 2 2 2 0 Regulator of G protein signaling domain Pkinase PF00069.25 CRK14325.1 - 3.2e-08 33.3 0.0 0.00029 20.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain JSRP PF15312.6 CRK14325.1 - 0.045 13.7 0.0 0.093 12.7 0.0 1.5 1 0 0 1 1 1 0 Junctional sarcoplasmic reticulum protein Pkinase_Tyr PF07714.17 CRK14325.1 - 0.07 12.4 0.0 0.91 8.7 0.0 2.0 2 0 0 2 2 2 0 Protein tyrosine kinase Kinase-like PF14531.6 CRK14325.1 - 0.096 12.0 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Sugar_tr PF00083.24 CRK14326.1 - 3.3e-103 346.0 21.5 8.4e-78 262.2 14.1 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CRK14326.1 - 1.9e-22 79.7 28.4 1.9e-22 79.7 28.4 2.3 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2070 PF09843.9 CRK14326.1 - 1.5 7.0 18.5 0.8 7.9 1.3 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) MFS_1 PF07690.16 CRK14327.1 - 3.9e-37 128.0 39.4 3.9e-37 128.0 39.4 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK14327.1 - 3.6e-10 39.3 9.1 3.6e-10 39.3 9.1 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter adh_short PF00106.25 CRK14328.1 - 7e-22 77.8 0.0 9.6e-22 77.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK14328.1 - 6.2e-17 61.9 0.0 1.5e-16 60.7 0.0 1.5 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK14328.1 - 7.4e-06 26.0 1.5 4e-05 23.6 1.5 1.9 1 1 0 1 1 1 1 KR domain Abhydrolase_3 PF07859.13 CRK14329.1 - 7.2e-55 186.1 0.0 2.3e-54 184.5 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF2235 PF09994.9 CRK14329.1 - 5.5e-44 150.6 0.2 8.6e-44 150.0 0.2 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) COesterase PF00135.28 CRK14329.1 - 1.3e-12 47.4 0.1 2.6e-12 46.4 0.1 1.4 1 0 0 1 1 1 1 Carboxylesterase family MMR_HSR1 PF01926.23 CRK14329.1 - 1.6e-05 25.0 0.0 4.3e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CRK14329.1 - 2.8e-05 24.1 0.0 8.3e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 RsgA GTPase Septin PF00735.18 CRK14329.1 - 0.00059 19.2 0.2 0.014 14.7 0.0 2.4 3 0 0 3 3 3 1 Septin Roc PF08477.13 CRK14329.1 - 0.00069 19.8 0.0 0.011 16.0 0.0 2.3 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CRK14329.1 - 0.0014 18.3 0.1 0.028 14.0 0.0 2.7 2 1 0 2 2 2 1 Ras family ABC_tran PF00005.27 CRK14329.1 - 0.0017 18.9 0.0 0.0091 16.5 0.0 2.3 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 CRK14329.1 - 0.012 15.9 0.0 0.047 14.0 0.0 2.0 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.18 CRK14329.1 - 0.019 14.5 0.0 0.12 11.9 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_29 PF13555.6 CRK14329.1 - 0.026 14.3 0.0 0.055 13.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Peptidase_S9 PF00326.21 CRK14329.1 - 0.045 13.2 0.1 6.1 6.3 0.0 2.7 3 0 0 3 3 3 0 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 CRK14329.1 - 0.047 14.3 2.3 0.13 12.8 2.3 1.8 1 0 0 1 1 1 0 Alpha/beta hydrolase family G-alpha PF00503.20 CRK14329.1 - 0.082 12.0 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit RNA_helicase PF00910.22 CRK14329.1 - 0.14 12.5 0.0 1.9 8.9 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 CRK14329.1 - 0.15 11.7 0.0 0.41 10.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 CRK14329.1 - 0.18 11.0 0.0 0.35 10.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Rad17 PF03215.15 CRK14329.1 - 0.19 11.6 0.0 0.38 10.7 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain RPN6_N PF18055.1 CRK14332.1 - 7.5e-63 210.1 10.0 8.3e-47 158.4 2.0 3.4 5 0 0 5 5 3 2 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 CRK14332.1 - 5.7e-21 75.0 0.3 3.5e-20 72.5 0.2 2.5 3 0 0 3 3 1 1 PCI domain RPN6_C_helix PF18503.1 CRK14332.1 - 3.7e-09 36.2 0.2 8.8e-09 35.0 0.2 1.7 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_MalT PF17874.1 CRK14332.1 - 7.2e-08 32.2 17.1 0.00022 20.7 1.8 3.2 3 2 0 3 3 3 2 MalT-like TPR region DUF410 PF04190.13 CRK14332.1 - 1.3e-05 25.2 3.1 0.018 14.9 0.1 3.3 3 1 0 3 3 3 2 Protein of unknown function (DUF410) TPR_12 PF13424.6 CRK14332.1 - 1.6e-05 25.1 28.8 0.05 13.9 1.3 6.7 6 1 2 8 8 8 2 Tetratricopeptide repeat TPR_4 PF07721.14 CRK14332.1 - 6.3e-05 23.2 0.1 1.7 9.5 0.0 3.6 2 0 0 2 2 2 2 Tetratricopeptide repeat DDRGK PF09756.9 CRK14332.1 - 0.00031 20.4 0.2 0.00031 20.4 0.2 2.0 2 0 0 2 2 2 1 DDRGK domain TPR_21 PF09976.9 CRK14332.1 - 0.0043 16.8 17.3 0.33 10.6 3.6 4.4 3 2 0 3 3 3 2 Tetratricopeptide repeat-like domain TPR_2 PF07719.17 CRK14332.1 - 0.011 15.7 7.8 46 4.5 0.0 6.6 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_7 PF13176.6 CRK14332.1 - 0.019 15.0 1.9 0.6 10.3 0.2 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Flt3_lig PF02947.14 CRK14332.1 - 0.02 15.1 0.4 8.6 6.5 0.0 3.4 3 0 0 3 3 3 0 flt3 ligand SesA PF17107.5 CRK14332.1 - 0.03 14.5 7.0 12 6.1 0.0 4.8 5 1 1 6 6 6 0 N-terminal domain on NACHT_NTPase and P-loop NTPases SbsC_C PF18058.1 CRK14332.1 - 0.047 13.9 5.2 2.6 8.3 0.0 3.3 3 1 1 4 4 3 0 SbsC C-terminal domain DprA_WH PF17782.1 CRK14332.1 - 0.049 13.8 0.5 0.5 10.5 0.0 2.9 4 0 0 4 4 3 0 DprA winged helix domain EST1 PF10374.9 CRK14332.1 - 0.08 13.6 0.6 22 5.7 0.0 3.3 3 0 0 3 3 3 0 Telomerase activating protein Est1 Mt_ATP-synt_B PF05405.14 CRK14332.1 - 0.1 12.2 4.9 3.3 7.3 0.1 3.1 3 0 0 3 3 3 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) TPR_16 PF13432.6 CRK14332.1 - 0.17 12.6 13.6 12 6.6 0.2 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4398 PF14346.6 CRK14332.1 - 1.2 9.8 18.8 1.3 9.7 0.2 4.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4398) Sof1 PF04158.14 CRK14333.1 - 4.2e-30 103.9 15.6 7.4e-30 103.1 15.6 1.4 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 CRK14333.1 - 5.4e-23 80.8 10.9 1.5e-06 28.8 0.0 6.1 7 0 0 7 7 7 4 WD domain, G-beta repeat HET PF06985.11 CRK14333.1 - 7.6e-18 65.3 1.3 1.9e-17 64.0 0.0 2.3 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) ANAPC4_WD40 PF12894.7 CRK14333.1 - 2.6e-07 30.8 0.0 0.0057 16.9 0.0 3.9 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 CRK14333.1 - 0.0041 17.1 0.0 4.8 7.3 0.0 3.8 2 2 2 4 4 4 1 Ciliary BBSome complex subunit 2, middle region AIP3 PF03915.13 CRK14334.1 - 9.3e-154 512.4 11.7 1.6e-153 511.7 7.0 2.5 2 0 0 2 2 2 1 Actin interacting protein 3 FAD_binding_3 PF01494.19 CRK14334.1 - 2.2e-20 73.2 0.9 4.1e-19 69.0 0.9 2.6 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 CRK14334.1 - 1.4e-05 25.2 0.0 4.2e-05 23.7 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 CRK14334.1 - 0.00022 20.4 0.0 0.0081 15.3 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 CRK14334.1 - 0.00045 19.9 0.3 0.0014 18.3 0.3 1.8 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 CRK14334.1 - 0.00097 19.6 0.0 0.0059 17.1 0.0 2.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CRK14334.1 - 0.0011 18.3 0.0 0.0021 17.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CRK14334.1 - 0.0013 17.6 0.0 0.0021 16.8 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein SE PF08491.10 CRK14334.1 - 0.0021 17.2 0.0 0.0044 16.1 0.0 1.5 1 0 0 1 1 1 1 Squalene epoxidase Trp_halogenase PF04820.14 CRK14334.1 - 0.01 14.7 0.0 0.032 13.1 0.0 1.7 2 0 0 2 2 2 0 Tryptophan halogenase ApbA PF02558.16 CRK14334.1 - 0.028 14.1 0.0 0.071 12.8 0.0 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.6 CRK14334.1 - 0.03 14.3 0.1 0.1 12.6 0.0 2.0 2 0 0 2 2 1 0 FAD-NAD(P)-binding NAD_Gly3P_dh_N PF01210.23 CRK14334.1 - 0.037 14.0 0.1 1.6 8.6 0.0 2.9 3 0 0 3 3 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FliL PF03748.14 CRK14334.1 - 0.051 14.2 4.6 4.1 8.1 0.1 3.9 3 0 0 3 3 2 0 Flagellar basal body-associated protein FliL RMMBL PF07521.12 CRK14334.1 - 0.071 13.1 0.4 20 5.2 0.0 2.6 2 0 0 2 2 2 0 Zn-dependent metallo-hydrolase RNA specificity domain FAD_binding_2 PF00890.24 CRK14334.1 - 0.081 12.0 0.1 0.15 11.1 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain NPV_P10 PF05531.12 CRK14334.1 - 0.11 12.9 6.5 0.11 12.9 0.5 3.6 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Lectin_N PF03954.14 CRK14334.1 - 0.16 11.7 0.0 0.16 11.7 0.0 3.4 4 0 0 4 4 4 0 Hepatic lectin, N-terminal domain Thi4 PF01946.17 CRK14334.1 - 0.17 11.1 0.0 0.31 10.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Wtap PF17098.5 CRK14334.1 - 0.59 10.0 5.6 0.18 11.7 0.3 2.8 3 0 0 3 3 3 0 WTAP/Mum2p family DUF4407 PF14362.6 CRK14334.1 - 4.5 6.5 8.4 0.67 9.2 0.1 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Med11 PF10280.9 CRK14334.1 - 5.3 7.5 6.9 2.3 8.7 0.1 3.6 4 0 0 4 4 4 0 Mediator complex protein Mak10 PF04112.13 CRK14335.1 - 7e-59 198.1 0.0 2.8e-58 196.2 0.0 1.9 2 0 0 2 2 2 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase ATP-synt_Eps PF04627.13 CRK14335.1 - 5.7e-19 67.8 1.8 1.1e-18 67.0 1.8 1.5 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Mito_carr PF00153.27 CRK14338.1 - 4.4e-49 164.4 3.6 3.1e-15 55.8 0.0 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein Myb_DNA-binding PF00249.31 CRK14338.1 - 7.7e-08 32.4 0.0 0.0031 17.7 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 CRK14338.1 - 0.05 13.5 1.4 0.41 10.6 0.1 2.5 2 0 0 2 2 2 0 Myb DNA-binding like DS PF01916.17 CRK14339.1 - 7.3e-131 435.7 0.0 8.4e-131 435.5 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Inhibitor_I10 PF12559.8 CRK14339.1 - 0.11 12.8 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 Serine endopeptidase inhibitors Pro_isomerase PF00160.21 CRK14340.1 - 1.2e-40 139.3 0.0 3.9e-40 137.7 0.0 1.9 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD HSF_DNA-bind PF00447.17 CRK14341.1 - 7.5e-28 97.0 0.2 1.6e-27 96.0 0.2 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding Ets PF00178.22 CRK14341.1 - 0.14 12.6 0.0 0.43 11.1 0.0 1.7 1 0 0 1 1 1 0 Ets-domain AD PF09793.9 CRK14341.1 - 0.55 10.4 2.7 0.47 10.6 0.2 2.1 2 0 0 2 2 2 0 Anticodon-binding domain tRNA_int_end_N2 PF12928.7 CRK14343.1 - 1.8e-17 63.2 0.0 3.4e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term Arrestin_C PF02752.22 CRK14344.1 - 5.7e-15 56.0 0.3 1.7e-14 54.4 0.0 1.9 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain MFS_1 PF07690.16 CRK14345.1 - 1.2e-35 123.1 100.0 3.1e-14 52.7 37.4 4.0 2 2 1 3 3 3 3 Major Facilitator Superfamily TRI12 PF06609.13 CRK14345.1 - 2.3e-08 32.9 38.5 2.3e-05 23.1 9.7 2.4 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Xpo1 PF08389.12 CRK14345.1 - 0.0028 17.7 0.2 3.4 7.7 0.0 2.3 2 0 0 2 2 2 2 Exportin 1-like protein Chlam_PMP PF02415.17 CRK14345.1 - 0.49 11.0 18.7 9 7.0 0.0 5.5 5 0 0 5 5 5 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat RRM_1 PF00076.22 CRK14346.1 - 1.4e-43 146.6 0.8 4.7e-20 71.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cyt-b5 PF00173.28 CRK14346.1 - 5.1e-18 65.0 2.1 6.6e-18 64.6 0.2 2.2 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 CRK14346.1 - 1.1e-11 45.2 14.5 1.8e-11 44.5 14.5 1.3 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily Nup35_RRM_2 PF14605.6 CRK14346.1 - 0.0017 18.3 0.0 1.5 8.9 0.0 3.4 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif DUF1866 PF08952.11 CRK14346.1 - 0.0045 16.9 0.0 0.093 12.6 0.0 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF1866) RRM_occluded PF16842.5 CRK14346.1 - 0.01 15.7 0.0 1.1 9.1 0.0 3.1 3 0 0 3 3 3 0 Occluded RNA-recognition motif RRM_3 PF08777.11 CRK14346.1 - 0.012 15.7 0.3 0.34 11.0 0.0 2.7 2 2 0 2 2 2 0 RNA binding motif RRM_7 PF16367.5 CRK14346.1 - 0.13 12.4 0.1 3.5 7.8 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif tRNA_int_end_N2 PF12928.7 CRK14347.1 - 1.7e-17 63.3 0.1 2.9e-17 62.6 0.1 1.4 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term CENP-B_dimeris PF09026.10 CRK14347.1 - 2 8.8 8.6 0.99 9.8 0.3 3.1 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Arrestin_C PF02752.22 CRK14348.1 - 6.3e-11 42.9 0.2 2.6e-10 40.9 0.2 2.1 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain RRM_1 PF00076.22 CRK14349.1 - 5.1e-44 148.0 0.8 3.4e-20 71.6 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 CRK14349.1 - 7.4e-24 84.7 0.3 2.3e-23 83.1 0.3 1.9 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein Nup35_RRM_2 PF14605.6 CRK14349.1 - 0.0011 18.9 0.0 1.1 9.3 0.0 3.1 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 CRK14349.1 - 0.0037 17.1 0.0 0.64 9.9 0.0 3.1 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_3 PF08777.11 CRK14349.1 - 0.0045 17.0 0.5 0.35 10.9 0.0 3.3 3 1 0 3 3 3 1 RNA binding motif RRM_7 PF16367.5 CRK14349.1 - 0.076 13.1 0.1 2.6 8.2 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif PHM7_cyt PF14703.6 CRK14349.1 - 0.12 12.6 0.1 1.8 8.7 0.1 2.9 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter RRM_5 PF13893.6 CRK14349.1 - 0.2 11.3 0.0 0.47 10.0 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Het-C PF07217.11 CRK14350.1 - 7.7e-281 932.6 0.0 9.2e-281 932.3 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Beach PF02138.18 CRK14350.1 - 0.21 10.9 0.0 0.34 10.3 0.0 1.2 1 0 0 1 1 1 0 Beige/BEACH domain Extensin_2 PF04554.13 CRK14350.1 - 3.5 7.8 64.7 1.8e+04 -20.4 64.7 2.8 1 1 0 1 1 1 0 Extensin-like region PP2C PF00481.21 CRK14352.1 - 1.1e-30 107.1 0.0 1.3e-21 77.4 0.0 3.2 2 1 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 CRK14352.1 - 0.0011 18.7 0.1 0.0048 16.6 0.0 2.0 2 0 0 2 2 2 1 Protein phosphatase 2C BTB PF00651.31 CRK14353.1 - 0.1 12.8 0.0 1.5 9.1 0.1 2.3 2 0 0 2 2 2 0 BTB/POZ domain CDP-OH_P_transf PF01066.21 CRK14354.1 - 3.5e-12 46.9 0.8 3.5e-12 46.9 0.8 2.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Thermopsin PF05317.11 CRK14354.1 - 0.046 13.2 0.1 0.078 12.4 0.1 1.3 1 0 0 1 1 1 0 Thermopsin OMPdecase PF00215.24 CRK14356.1 - 2.9e-54 184.0 0.2 5.8e-53 179.8 0.0 2.6 3 0 0 3 3 3 1 Orotidine 5'-phosphate decarboxylase / HUMPS family OMPdecase PF00215.24 CRK14357.1 - 3.3e-46 157.7 0.0 3.6e-46 157.6 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family OMPdecase PF00215.24 CRK14358.1 - 1.8e-32 112.8 0.0 3.6e-32 111.8 0.0 1.4 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Fungal_trans PF04082.18 CRK14358.1 - 2.1e-16 59.8 0.1 4.9e-07 29.0 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK14358.1 - 1.4e-05 25.1 13.0 1.4e-05 25.1 13.0 2.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_transf_34 PF05637.12 CRK14358.1 - 1.6e-05 24.7 0.2 3.9e-05 23.5 0.2 1.6 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Nucleotid_trans PF03407.16 CRK14358.1 - 2.1e-05 24.6 0.0 4.5e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Sec1 PF00995.23 CRK14358.1 - 0.00034 20.0 0.2 0.75 8.9 0.0 2.5 2 0 0 2 2 2 2 Sec1 family ComC PF03047.14 CRK14358.1 - 0.0027 17.4 1.1 3 7.7 0.1 2.6 2 0 0 2 2 2 2 COMC family Stb3 PF10330.9 CRK14358.1 - 0.05 13.6 0.2 46 4.1 0.0 3.5 3 0 0 3 3 3 0 Putative Sin3 binding protein Cytochrom_CIII PF02085.16 CRK14358.1 - 0.14 12.5 5.8 0.33 11.3 5.8 1.6 1 0 0 1 1 1 0 Class III cytochrome C family Cytochrome_C7 PF14522.6 CRK14358.1 - 0.16 12.0 7.2 0.34 10.9 7.2 1.5 1 0 0 1 1 1 0 Cytochrome c7 and related cytochrome c Glyco_transf_34 PF05637.12 CRK14359.1 - 1.8e-06 27.9 0.6 4.3e-06 26.6 0.6 1.6 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Nucleotid_trans PF03407.16 CRK14359.1 - 2.7e-06 27.5 0.0 3.9e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase DUF273 PF03314.14 CRK14359.1 - 0.031 13.9 0.0 0.074 12.6 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function, DUF273 SRP19 PF01922.17 CRK14360.1 - 2e-30 105.6 0.0 4.9e-30 104.3 0.0 1.7 1 0 0 1 1 1 1 SRP19 protein zf-CCCH PF00642.24 CRK14360.1 - 0.86 9.6 4.4 2 8.4 4.4 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 CRK14360.1 - 1.2 9.8 6.0 0.37 11.5 1.5 2.4 1 1 1 2 2 2 0 Torus domain Dynactin PF12455.8 CRK14361.1 - 7.2e-111 370.0 8.5 7.2e-111 370.0 8.5 4.6 5 0 0 5 5 5 1 Dynein associated protein CAP_GLY PF01302.25 CRK14361.1 - 7e-47 157.3 4.8 1.3e-22 79.6 0.4 2.4 2 0 0 2 2 2 2 CAP-Gly domain TIP49_C PF17856.1 CRK14361.1 - 1.3e-24 86.1 0.1 3.4e-24 84.7 0.1 1.8 1 0 0 1 1 1 1 TIP49 AAA-lid domain HMG_box PF00505.19 CRK14361.1 - 2.3e-20 72.8 0.3 8.6e-20 70.9 0.3 2.1 1 0 0 1 1 1 1 HMG (high mobility group) box TIP49 PF06068.13 CRK14361.1 - 9.9e-06 25.0 0.0 2.1e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain DUF2353 PF09789.9 CRK14361.1 - 4.9e-05 22.9 54.4 0.00029 20.3 22.0 5.2 5 1 1 6 6 6 3 Uncharacterized coiled-coil protein (DUF2353) HMG_box_2 PF09011.10 CRK14361.1 - 0.00028 21.4 0.2 0.0013 19.3 0.2 2.3 1 0 0 1 1 1 1 HMG-box domain Endotoxin_N PF03945.14 CRK14361.1 - 0.0071 16.1 1.5 2.2 7.9 0.0 3.0 2 0 0 2 2 2 2 delta endotoxin, N-terminal domain Leuk-A4-hydro_C PF09127.11 CRK14361.1 - 0.25 11.5 5.8 8.9 6.4 0.5 2.9 2 0 0 2 2 2 0 Leukotriene A4 hydrolase, C-terminal DUF4988 PF16378.5 CRK14361.1 - 2.6 7.7 7.1 3.3 7.3 2.8 3.2 2 0 0 2 2 2 0 Domain of unknown function TIP49 PF06068.13 CRK14362.1 - 1.1e-166 554.3 0.2 1.4e-166 554.0 0.2 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 CRK14362.1 - 1.4e-25 89.2 0.1 3.7e-25 87.8 0.1 1.8 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 CRK14362.1 - 4.6e-11 43.3 0.2 1.7e-06 28.5 0.1 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CRK14362.1 - 9.4e-10 38.4 0.3 4.9e-07 29.6 0.0 3.0 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CRK14362.1 - 0.00023 21.4 0.3 0.31 11.3 0.0 2.6 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CRK14362.1 - 0.00087 19.7 0.1 0.0057 17.1 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 CRK14362.1 - 0.0017 18.6 0.1 0.0035 17.6 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CRK14362.1 - 0.0035 17.7 2.7 0.084 13.2 2.7 2.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CRK14362.1 - 0.0064 16.5 0.1 0.14 12.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 CRK14362.1 - 0.0092 15.6 0.1 0.049 13.2 0.1 2.0 2 0 0 2 2 2 1 AAA domain DnaB_C PF03796.15 CRK14362.1 - 0.013 14.9 0.0 0.028 13.8 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_18 PF13238.6 CRK14362.1 - 0.014 15.9 0.0 0.04 14.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 CRK14362.1 - 0.02 14.6 0.1 1.2 8.8 0.1 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 CRK14362.1 - 0.021 14.1 0.2 0.061 12.6 0.1 1.8 2 0 0 2 2 2 0 Zeta toxin Mg_chelatase PF01078.21 CRK14362.1 - 0.021 14.2 0.2 0.44 9.9 0.1 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 CRK14362.1 - 0.025 14.3 0.2 0.059 13.1 0.2 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF2075 PF09848.9 CRK14362.1 - 0.089 12.0 0.4 0.15 11.2 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) TFIID-31kDa PF02291.15 CRK14362.1 - 0.12 12.4 0.0 1.8 8.6 0.0 2.3 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit AAA_7 PF12775.7 CRK14362.1 - 0.14 11.6 0.3 0.29 10.6 0.0 1.6 2 0 0 2 2 1 0 P-loop containing dynein motor region TFIID-18kDa PF02269.16 CRK14363.1 - 1.9e-16 59.8 0.0 2.7e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CENP-S PF15630.6 CRK14363.1 - 0.035 14.5 0.0 0.058 13.8 0.0 1.3 1 0 0 1 1 1 0 CENP-S protein Bromo_TP PF07524.13 CRK14363.1 - 0.063 13.3 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated DUF1242 PF06842.12 CRK14364.1 - 1.5e-14 53.4 0.2 2.8e-14 52.6 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) Tcp11 PF05794.13 CRK14365.1 - 5.2e-108 362.0 0.0 8e-108 361.4 0.0 1.3 1 0 0 1 1 1 1 T-complex protein 11 CDC45 PF02724.14 CRK14366.1 - 0.0044 15.4 2.4 0.006 14.9 2.4 1.1 1 0 0 1 1 1 1 CDC45-like protein RP-C_C PF11800.8 CRK14366.1 - 0.0086 16.2 0.9 0.022 14.9 0.9 1.7 1 0 0 1 1 1 1 Replication protein C C-terminal region SDA1 PF05285.12 CRK14366.1 - 0.027 13.9 3.7 0.039 13.4 3.7 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 CRK14366.1 - 0.077 12.3 7.5 0.1 11.9 7.5 1.1 1 0 0 1 1 1 0 BUD22 DUF1917 PF08939.10 CRK14366.1 - 0.28 11.0 1.0 0.48 10.3 0.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1917) Nop14 PF04147.12 CRK14366.1 - 1.3 7.1 6.6 1.9 6.6 6.6 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 CRK14366.1 - 3.2 7.0 6.5 6.3 6.0 6.5 1.4 1 0 0 1 1 1 0 NOA36 protein Spt5_N PF11942.8 CRK14366.1 - 6.9 7.7 14.5 14 6.7 14.5 1.5 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Glyco_hydro_18 PF00704.28 CRK14367.1 - 1e-41 143.7 1.2 1.2e-41 143.5 0.2 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 LysM PF01476.20 CRK14367.1 - 7.2e-07 29.2 0.0 0.018 15.1 0.0 3.3 3 0 0 3 3 3 2 LysM domain FCSD-flav_bind PF09242.11 CRK14367.1 - 0.19 12.1 0.7 0.58 10.5 0.4 1.9 2 0 0 2 2 2 0 Flavocytochrome c sulphide dehydrogenase, flavin-binding CcmH PF03918.14 CRK14369.1 - 0.0005 19.4 0.0 3.1 7.1 0.0 3.9 5 0 0 5 5 5 2 Cytochrome C biogenesis protein HSDR_N_2 PF13588.6 CRK14369.1 - 0.0014 18.6 0.5 9.3 6.3 0.0 4.2 5 0 0 5 5 5 2 Type I restriction enzyme R protein N terminus (HSDR_N) CarbpepA_inh PF02977.15 CRK14369.1 - 0.28 11.0 10.2 15 5.5 0.1 5.6 5 0 0 5 5 5 0 Carboxypeptidase A inhibitor Adenyl_transf PF04439.12 CRK14369.1 - 0.83 8.7 2.4 22 4.0 0.0 3.4 5 0 0 5 5 5 0 Streptomycin adenylyltransferase Fungal_trans PF04082.18 CRK14370.1 - 1.8e-09 37.1 0.2 3.4e-09 36.1 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain CRAL_TRIO PF00650.20 CRK14372.1 - 3.8e-11 43.0 0.0 5.6e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CRK14372.1 - 0.00018 21.6 0.0 0.00033 20.8 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain DUF2456 PF10445.9 CRK14373.1 - 7.9e-13 48.3 0.5 1.6e-12 47.3 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2456) GCP_N_terminal PF17681.1 CRK14374.1 - 0.12 12.0 0.4 0.24 11.0 0.0 1.6 2 0 0 2 2 2 0 Gamma tubulin complex component N-terminal SOBP PF15279.6 CRK14375.1 - 9.9 6.7 19.5 10 6.6 4.3 2.4 2 0 0 2 2 2 0 Sine oculis-binding protein CRAL_TRIO PF00650.20 CRK14376.1 - 1.8e-11 44.0 0.0 2.6e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CRK14376.1 - 0.00017 21.7 0.0 0.00032 20.8 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain PRCC PF10253.9 CRK14376.1 - 8.8 7.1 12.3 15 6.3 12.3 1.4 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting DUF2456 PF10445.9 CRK14377.1 - 6.9e-16 58.1 0.1 1.8e-15 56.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2456) 7tm_1 PF00001.21 CRK14377.1 - 0.11 11.8 0.0 0.24 10.7 0.0 1.4 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Glyco_hydro_61 PF03443.14 CRK14378.1 - 3.3e-100 334.2 0.0 2.1e-61 207.5 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 61 Peptidase_M35 PF02102.15 CRK14379.1 - 6.9e-59 199.5 1.0 9.1e-59 199.1 1.0 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 CRK14379.1 - 3.5e-37 128.2 0.1 6.1e-37 127.4 0.1 1.4 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.6 CRK14379.1 - 0.0031 17.1 0.8 0.026 14.1 0.8 2.3 1 1 0 1 1 1 1 Putative peptidase family Glyco_hydro_61 PF03443.14 CRK14381.1 - 1e-11 45.2 0.0 1.2e-11 44.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Ribosomal_S30 PF04758.14 CRK14382.1 - 1.4e-29 102.1 9.5 1.5e-29 101.9 9.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 GATA PF00320.27 CRK14383.1 - 7.7e-33 111.8 12.0 3.8e-16 58.4 2.3 2.5 2 0 0 2 2 2 2 GATA zinc finger DUF1752 PF08550.10 CRK14383.1 - 7.1e-13 48.1 0.5 1.8e-12 46.9 0.5 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Auto_anti-p27 PF06677.12 CRK14383.1 - 0.29 11.3 8.7 3.8 7.7 1.3 2.3 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DZR PF12773.7 CRK14383.1 - 2.1 8.4 9.7 28 4.8 1.4 3.0 2 2 2 4 4 4 0 Double zinc ribbon Pkinase PF00069.25 CRK14385.1 - 1.7e-60 204.7 0.0 1.4e-59 201.6 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK14385.1 - 2.7e-28 99.0 0.5 1e-19 70.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 CRK14385.1 - 5.1e-05 23.9 0.4 0.00019 22.0 0.4 2.1 1 0 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.23 CRK14385.1 - 0.0011 18.9 0.8 0.11 12.5 0.1 3.4 3 1 1 4 4 4 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CRK14385.1 - 0.0064 15.8 0.1 0.025 13.9 0.0 1.9 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.14 CRK14385.1 - 0.034 13.5 0.0 0.065 12.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CRK14385.1 - 0.038 12.9 0.0 0.099 11.6 0.0 1.3 1 1 0 1 1 1 0 Haspin like kinase domain Wbp11 PF09429.10 CRK14386.1 - 2.6e-23 82.2 12.6 2.6e-23 82.2 12.6 2.1 2 0 0 2 2 2 1 WW domain binding protein 11 Lipoprotein_7 PF01540.16 CRK14386.1 - 0.055 12.8 3.0 0.078 12.3 3.0 1.1 1 0 0 1 1 1 0 Adhesin lipoprotein MFS_1 PF07690.16 CRK14388.1 - 4e-37 128.0 51.6 5.9e-37 127.4 51.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DFP PF04127.15 CRK14388.1 - 1.3e-12 47.9 0.0 8.1e-05 22.5 0.0 3.2 2 1 0 3 3 3 3 DNA / pantothenate metabolism flavoprotein Sugar_tr PF00083.24 CRK14388.1 - 5e-11 42.1 28.6 5.5e-07 28.8 6.8 2.5 2 1 1 3 3 3 2 Sugar (and other) transporter Dmrt1 PF12374.8 CRK14388.1 - 0.66 10.5 4.4 0.23 11.9 0.6 2.2 2 0 0 2 2 2 0 Double-sex mab3 related transcription factor 1 Acatn PF13000.7 CRK14389.1 - 2.5e-161 537.9 19.1 2.5e-82 277.2 9.0 3.3 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 CENP-O PF09496.10 CRK14390.1 - 4.5e-67 226.1 0.1 9.7e-67 225.0 0.0 1.5 2 0 0 2 2 2 1 Cenp-O kinetochore centromere component FlxA PF14282.6 CRK14390.1 - 0.064 13.2 1.7 0.13 12.2 1.7 1.5 1 0 0 1 1 1 0 FlxA-like protein Phage_GP20 PF06810.11 CRK14390.1 - 0.4 10.5 3.9 0.17 11.7 1.1 1.7 2 0 0 2 2 2 0 Phage minor structural protein GP20 MFS_1 PF07690.16 CRK14392.1 - 6.5e-39 133.8 28.8 2.4e-38 132.0 15.7 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Yae1_N PF09811.9 CRK14392.1 - 1.2e-12 47.3 1.9 2.4e-12 46.3 1.9 1.6 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Sugar_tr PF00083.24 CRK14392.1 - 3.3e-10 39.4 1.6 6.3e-10 38.5 1.6 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 CRK14392.1 - 0.0021 16.6 0.3 0.003 16.0 0.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 CRK14392.1 - 0.0089 14.9 0.0 0.037 12.9 0.0 2.2 1 1 0 1 1 1 1 MFS_1 like family Pyridoxal_deC PF00282.19 CRK14394.1 - 3.7e-61 206.9 0.0 5.1e-61 206.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 CRK14394.1 - 2.4e-05 23.5 0.0 5.8e-05 22.2 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V AMP-binding PF00501.28 CRK14395.1 - 6.1e-76 255.7 0.1 1e-75 254.9 0.1 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CRK14395.1 - 9.9e-13 48.9 0.5 2.7e-12 47.5 0.5 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Roc PF08477.13 CRK14396.1 - 2.1e-05 24.7 0.1 2.3e-05 24.6 0.1 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CRK14396.1 - 6.4e-05 22.6 0.1 7e-05 22.5 0.1 1.1 1 0 0 1 1 1 1 Ras family RsgA_GTPase PF03193.16 CRK14396.1 - 0.0006 19.8 0.1 0.0006 19.8 0.1 1.1 1 0 0 1 1 1 1 RsgA GTPase AAA_24 PF13479.6 CRK14396.1 - 0.0038 17.0 0.0 0.0041 16.9 0.0 1.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CRK14396.1 - 0.0043 17.4 0.1 0.0043 17.4 0.1 1.0 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 CRK14396.1 - 0.01 15.8 0.1 0.012 15.5 0.1 1.1 1 0 0 1 1 1 0 NACHT domain MMR_HSR1 PF01926.23 CRK14396.1 - 0.01 15.9 0.1 0.011 15.8 0.1 1.1 1 0 0 1 1 1 0 50S ribosome-binding GTPase DAP3 PF10236.9 CRK14396.1 - 0.02 14.1 0.2 0.02 14.1 0.2 1.0 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_29 PF13555.6 CRK14396.1 - 0.024 14.4 0.1 0.024 14.4 0.1 1.1 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 CRK14396.1 - 0.025 15.1 0.1 0.025 15.1 0.1 1.1 1 0 0 1 1 1 0 ABC transporter Septin PF00735.18 CRK14396.1 - 0.029 13.7 0.1 0.029 13.7 0.1 1.0 1 0 0 1 1 1 0 Septin AAA_22 PF13401.6 CRK14396.1 - 0.03 14.6 0.0 0.03 14.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CRK14396.1 - 0.031 13.8 0.1 0.031 13.8 0.1 1.0 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 CRK14396.1 - 0.048 13.7 0.0 0.051 13.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.9 CRK14396.1 - 0.048 13.4 0.1 0.051 13.3 0.1 1.1 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation IIGP PF05049.13 CRK14396.1 - 0.048 12.7 0.0 0.048 12.7 0.0 1.0 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Sigma54_activat PF00158.26 CRK14396.1 - 0.049 13.3 0.0 0.049 13.3 0.0 1.0 1 0 0 1 1 1 0 Sigma-54 interaction domain TniB PF05621.11 CRK14396.1 - 0.067 12.6 0.1 0.067 12.6 0.1 1.0 1 0 0 1 1 1 0 Bacterial TniB protein G-alpha PF00503.20 CRK14396.1 - 0.083 12.0 0.1 0.083 12.0 0.1 1.0 1 0 0 1 1 1 0 G-protein alpha subunit MCM PF00493.23 CRK14396.1 - 0.091 11.8 0.1 0.091 11.8 0.1 1.0 1 0 0 1 1 1 0 MCM P-loop domain RNA_helicase PF00910.22 CRK14396.1 - 0.12 12.8 0.0 0.13 12.7 0.0 1.1 1 0 0 1 1 1 0 RNA helicase AAA_23 PF13476.6 CRK14396.1 - 0.18 12.3 0.1 0.2 12.2 0.1 1.1 1 0 0 1 1 1 0 AAA domain DnaJ PF00226.31 CRK14397.1 - 2.3e-09 37.2 0.3 1.5e-08 34.6 0.0 2.2 2 1 1 3 3 3 1 DnaJ domain SirA PF10747.9 CRK14397.1 - 0.0068 16.7 0.0 0.0087 16.4 0.0 1.2 1 0 0 1 1 1 1 Sporulation inhibitor of replication protein SirA RE_HindIII PF09518.10 CRK14397.1 - 0.11 11.7 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 HindIII restriction endonuclease DUF2284 PF10050.9 CRK14402.1 - 0.012 15.4 57.1 1.9 8.2 0.2 10.0 10 1 0 10 10 10 0 Predicted metal-binding protein (DUF2284) MFS_1 PF07690.16 CRK14405.1 - 1.2e-42 146.1 37.4 1.2e-42 146.1 37.4 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK14405.1 - 5.2e-07 28.9 28.1 0.00015 20.8 6.8 3.2 2 1 1 3 3 3 3 Sugar (and other) transporter MFS_3 PF05977.13 CRK14405.1 - 8.8e-05 21.1 6.4 8.8e-05 21.1 6.4 2.2 2 0 0 2 2 2 1 Transmembrane secretion effector MFS_1_like PF12832.7 CRK14405.1 - 2.1 7.1 14.8 0.28 10.0 7.3 2.2 2 0 0 2 2 2 0 MFS_1 like family 2OG-FeII_Oxy_2 PF13532.6 CRK14406.1 - 7.4e-20 72.0 0.0 1.3e-19 71.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Plus-3 PF03126.18 CRK14407.1 - 1.5e-31 109.1 0.0 3.6e-31 107.9 0.0 1.7 1 0 0 1 1 1 1 Plus-3 domain PLDc PF00614.22 CRK14407.1 - 1e-07 31.8 0.2 3e-07 30.3 0.2 1.9 1 0 0 1 1 1 1 Phospholipase D Active site motif PX PF00787.24 CRK14407.1 - 3.2e-06 27.1 0.0 3.7e-05 23.7 0.0 2.9 2 1 0 2 2 2 1 PX domain PLDc_2 PF13091.6 CRK14407.1 - 0.001 18.9 0.0 0.0026 17.6 0.0 1.6 1 0 0 1 1 1 1 PLD-like domain COQ7 PF03232.13 CRK14408.1 - 2e-18 66.8 0.0 2.7e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 CRK14408.1 - 0.0046 17.3 0.0 0.0056 17.1 0.0 1.1 1 0 0 1 1 1 1 Rubrerythrin Tubulin PF00091.25 CRK14409.1 - 3.9e-68 229.6 0.0 5.7e-68 229.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CRK14409.1 - 1.1e-45 154.9 0.5 1.7e-45 154.2 0.1 1.6 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CRK14409.1 - 1.9e-07 31.4 0.0 3.9e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 CRK14409.1 - 0.035 13.8 0.0 0.096 12.4 0.0 1.7 1 0 0 1 1 1 0 Tubulin domain PRK PF00485.18 CRK14411.1 - 0.00075 19.3 2.2 0.02 14.7 2.1 2.1 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 CRK14411.1 - 0.0022 18.5 1.0 0.023 15.3 0.2 2.3 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 CRK14411.1 - 0.013 14.7 0.0 0.021 14.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain DUF4813 PF16072.5 CRK14411.1 - 0.017 14.8 11.3 0.022 14.4 11.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) Zeta_toxin PF06414.12 CRK14411.1 - 0.017 14.4 0.1 0.031 13.6 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.6 CRK14411.1 - 0.079 13.4 1.0 2.9 8.3 0.2 2.2 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 CRK14411.1 - 0.14 11.9 0.1 0.24 11.1 0.1 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 CRK14411.1 - 0.15 12.3 2.1 1.1 9.4 0.1 2.3 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.17 CRK14411.1 - 0.17 11.6 0.1 3.5 7.3 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase GFO_IDH_MocA PF01408.22 CRK14412.1 - 5e-15 56.4 0.0 8.7e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 CRK14412.1 - 0.00023 21.2 0.0 0.00039 20.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain MFS_1 PF07690.16 CRK14413.1 - 6e-28 97.8 37.1 2.3e-27 95.8 37.1 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 CRK14413.1 - 1.1e-05 24.1 12.2 1.4e-05 23.8 12.2 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ATG22 PF11700.8 CRK14413.1 - 3.8e-05 22.5 1.5 3.8e-05 22.5 1.5 2.7 2 1 1 3 3 3 1 Vacuole effluxer Atg22 like MFS_1_like PF12832.7 CRK14413.1 - 9.8e-05 21.4 8.7 0.00016 20.6 8.7 1.4 1 0 0 1 1 1 1 MFS_1 like family Spore_III_AF PF09581.10 CRK14413.1 - 0.091 12.8 1.0 0.095 12.7 0.1 1.5 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) FSH1 PF03959.13 CRK14414.1 - 3.1e-27 95.6 0.0 7.1e-27 94.5 0.0 1.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 CRK14414.1 - 0.034 14.7 7.8 0.15 12.7 7.9 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family CDH PF02611.15 CRK14414.1 - 0.14 11.7 0.0 0.2 11.2 0.0 1.1 1 0 0 1 1 1 0 CDP-diacylglycerol pyrophosphatase UDPGT PF00201.18 CRK14415.1 - 4.8e-21 75.1 0.0 6.7e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CRK14415.1 - 5.6e-08 32.9 0.1 1.3e-07 31.8 0.0 1.5 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain Sulfate_transp PF00916.20 CRK14416.1 - 1.3e-99 333.5 21.7 1.7e-99 333.1 21.7 1.1 1 0 0 1 1 1 1 Sulfate permease family Lactamase_B PF00753.27 CRK14416.1 - 3.7e-10 40.1 4.6 1.2e-09 38.5 4.6 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily STAS PF01740.21 CRK14416.1 - 7.7e-09 35.2 0.0 1.7e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 STAS domain Lactamase_B_2 PF12706.7 CRK14416.1 - 0.021 14.4 0.4 0.054 13.0 0.4 1.7 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Transposase_21 PF02992.14 CRK14416.1 - 0.18 11.0 0.0 0.33 10.2 0.0 1.3 1 0 0 1 1 1 0 Transposase family tnp2 Asparaginase_2 PF01112.18 CRK14418.1 - 0.98 8.4 7.0 1.1 8.2 7.0 1.1 1 0 0 1 1 1 0 Asparaginase PRELI PF04707.14 CRK14421.1 - 3.5e-41 140.7 0.3 4.1e-41 140.4 0.3 1.1 1 0 0 1 1 1 1 PRELI-like family Amino_oxidase PF01593.24 CRK14422.1 - 7e-27 94.8 2.2 6.1e-16 58.7 0.0 3.8 2 1 2 4 4 4 3 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CRK14422.1 - 2.1e-11 43.9 0.1 5.2e-11 42.6 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 CRK14422.1 - 3.9e-09 36.7 0.1 0.28 11.2 0.0 3.4 3 0 0 3 3 3 3 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 CRK14422.1 - 2.1e-06 27.2 0.0 0.93 8.7 0.0 3.1 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CRK14422.1 - 1.5e-05 24.7 0.4 0.011 15.3 0.0 3.6 4 0 0 4 4 4 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CRK14422.1 - 2.1e-05 23.9 0.2 0.011 15.0 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Syja_N PF02383.18 CRK14422.1 - 0.0013 18.1 0.0 1.3 8.3 0.0 2.2 2 0 0 2 2 2 2 SacI homology domain Pyr_redox PF00070.27 CRK14422.1 - 0.0018 18.8 0.0 1.4 9.6 0.0 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase MBDa PF16564.5 CRK14422.1 - 0.0065 16.6 0.1 6.7 7.0 0.0 2.4 2 0 0 2 2 2 2 p55-binding region of Methyl-CpG-binding domain proteins MBD HI0933_like PF03486.14 CRK14422.1 - 0.0076 15.0 0.0 0.78 8.4 0.0 3.1 3 0 0 3 3 3 1 HI0933-like protein FAD_oxidored PF12831.7 CRK14422.1 - 0.039 13.3 0.0 0.057 12.8 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase PXT1 PF15214.6 CRK14422.1 - 0.04 14.3 7.9 2.3 8.6 0.8 3.0 2 0 0 2 2 2 0 Peroxisomal testis-specific protein 1 CtaG_Cox11 PF04442.14 CRK14424.1 - 5.8e-60 201.7 0.2 1.1e-59 200.8 0.0 1.5 2 0 0 2 2 2 1 Cytochrome c oxidase assembly protein CtaG/Cox11 FNIP_N PF14636.6 CRK14424.1 - 0.073 14.0 1.5 0.11 13.5 1.5 1.2 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus Ribosomal_L26 PF16906.5 CRK14426.1 - 3.4e-36 123.6 2.3 4.5e-36 123.2 2.3 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 CRK14426.1 - 8.7e-07 28.7 1.3 8.7e-07 28.7 1.3 2.2 2 0 0 2 2 2 1 KOW motif DUF1223 PF06764.11 CRK14426.1 - 0.12 12.4 0.1 0.14 12.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1223) PRAP PF15314.6 CRK14428.1 - 0.004 17.6 1.4 3.4 8.2 0.2 3.0 2 0 0 2 2 2 2 Proline-rich acidic protein 1, pregnancy-specific uterine Organ_specific PF10950.8 CRK14428.1 - 0.016 15.9 5.3 5 7.9 0.5 3.7 2 0 0 2 2 2 0 Organ specific protein DUF3316 PF11777.8 CRK14428.1 - 0.04 14.0 0.6 3.5 7.7 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3316) PyocinActivator PF11112.8 CRK14428.1 - 0.089 12.9 0.1 13 6.0 0.0 2.7 2 0 0 2 2 2 0 Pyocin activator protein PrtN DUF4320 PF14208.6 CRK14428.1 - 0.47 10.5 1.9 23 5.1 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4320) PIN_8 PF18476.1 CRK14428.1 - 7.6 6.3 16.6 12 5.7 4.2 2.5 2 0 0 2 2 2 0 PIN like domain Col_cuticle_N PF01484.17 CRK14432.1 - 3.2 7.9 4.0 5.8 7.1 4.0 1.4 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain Adaptin_N PF01602.20 CRK14436.1 - 3.9e-213 708.7 21.7 8.2e-120 400.8 8.2 3.1 2 1 1 3 3 3 3 Adaptin N terminal region Alpha_adaptin_C PF02296.16 CRK14436.1 - 2.3e-90 298.4 0.0 9.2e-44 148.2 0.0 2.7 2 0 0 2 2 2 2 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 CRK14436.1 - 1.2e-32 112.5 0.1 5.7e-15 55.6 0.0 2.6 2 0 0 2 2 2 2 Adaptin C-terminal domain Phage_Orf51 PF06194.11 CRK14436.1 - 0.0031 17.5 1.1 4.3 7.4 0.1 3.2 4 0 0 4 4 4 2 Phage Conserved Open Reading Frame 51 Xpo1 PF08389.12 CRK14436.1 - 0.0056 16.8 6.8 0.66 10.0 0.2 3.5 4 0 0 4 4 4 2 Exportin 1-like protein SBD PF17882.1 CRK14436.1 - 0.036 13.9 0.1 14 5.5 0.0 2.5 2 0 0 2 2 2 0 OAA-family lectin sugar binding domain F-box_5 PF18511.1 CRK14436.1 - 0.11 12.1 0.3 22 4.8 0.0 2.7 2 0 0 2 2 2 0 F-box Cas_Cas2CT1978 PF09707.10 CRK14436.1 - 0.11 12.5 0.9 21 5.3 0.1 2.9 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) Tmemb_161AB PF10268.9 CRK14436.1 - 0.12 11.0 1.1 10 4.6 0.1 2.3 2 0 0 2 2 2 0 Predicted transmembrane protein 161AB WRW PF10206.9 CRK14436.1 - 0.14 12.6 0.0 47 4.4 0.0 3.2 4 0 0 4 4 4 0 Mitochondrial F1F0-ATP synthase, subunit f DUF5631 PF18645.1 CRK14436.1 - 0.39 11.1 3.2 28 5.2 0.2 3.0 2 0 0 2 2 2 0 Family of unknown function (DUF5631) GlutR_dimer PF00745.20 CRK14436.1 - 3.2 8.2 7.0 14 6.2 0.1 3.8 5 0 0 5 5 5 0 Glutamyl-tRNAGlu reductase, dimerisation domain Ala_racemase_N PF01168.20 CRK14438.1 - 1.3e-24 87.1 0.3 1.5e-24 86.9 0.3 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Methyltransf_23 PF13489.6 CRK14441.1 - 1.7e-20 73.5 0.0 1.5e-11 44.5 0.0 2.3 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 CRK14441.1 - 1.7e-14 54.2 0.0 3.3e-07 30.9 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 CRK14441.1 - 9.3e-13 48.8 0.0 3e-06 27.9 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 CRK14441.1 - 3.1e-10 40.6 0.0 0.00019 22.1 0.0 3.3 2 2 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 CRK14441.1 - 2.3e-08 34.0 0.0 0.0015 18.3 0.0 3.8 4 0 0 4 4 4 2 Methyltransferase domain Methyltransf_7 PF03492.15 CRK14441.1 - 0.0017 17.6 0.0 1.5 8.0 0.0 2.2 2 0 0 2 2 2 2 SAM dependent carboxyl methyltransferase Ubie_methyltran PF01209.18 CRK14441.1 - 0.0053 16.1 0.0 0.1 11.9 0.0 2.3 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family P16-Arc PF04699.14 CRK14443.1 - 4.3e-84 280.4 0.0 2e-48 164.6 0.0 2.0 2 0 0 2 2 2 2 ARP2/3 complex 16 kDa subunit (p16-Arc) FAST_2 PF08368.12 CRK14443.1 - 0.032 15.0 0.0 18 6.2 0.0 2.5 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 2 Peptidase_M27 PF01742.17 CRK14443.1 - 0.32 10.1 0.0 23 3.9 0.0 2.3 2 0 0 2 2 2 0 Clostridial neurotoxin zinc protease TPR_4 PF07721.14 CRK14443.1 - 2.5 9.0 6.7 27 5.8 0.7 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat ATP-synt_ab PF00006.25 CRK14445.1 - 2.5e-55 187.4 0.0 3.5e-55 187.0 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain DUF5535 PF17687.1 CRK14445.1 - 0.043 14.0 0.0 0.07 13.3 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5535) DUF4230 PF14014.6 CRK14445.1 - 0.12 12.6 0.8 0.56 10.5 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4230) ATP-synt_ab PF00006.25 CRK14447.1 - 3.8e-64 216.3 0.0 5.6e-64 215.7 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain HMGL-like PF00682.19 CRK14447.1 - 1.2e-39 136.5 0.0 2.3e-38 132.3 0.0 2.2 1 1 0 1 1 1 1 HMGL-like ATP-synt_ab_N PF02874.23 CRK14447.1 - 2.5e-14 53.5 1.4 5.7e-14 52.4 1.4 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF5535 PF17687.1 CRK14447.1 - 0.13 12.5 0.0 0.32 11.2 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5535) Zn_clus PF00172.18 CRK14449.1 - 1.9 8.6 14.7 0.32 11.1 10.6 1.9 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2470 PF10615.9 CRK14450.1 - 1.6e-18 67.1 0.0 2.2e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) Phosphoesterase PF04185.14 CRK14453.1 - 7.5e-19 68.1 0.0 8.8e-18 64.6 0.0 2.4 3 0 0 3 3 3 1 Phosphoesterase family NPP1 PF05630.11 CRK14456.1 - 5.5e-17 62.5 0.1 9.2e-17 61.8 0.1 1.3 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Zn_clus PF00172.18 CRK14456.1 - 4e-08 33.2 8.6 8.3e-08 32.2 8.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain KRTAP PF11759.8 CRK14456.1 - 0.22 12.1 4.3 0.48 11.0 4.3 1.6 1 0 0 1 1 1 0 Keratin-associated matrix PHD_2 PF13831.6 CRK14456.1 - 0.37 10.4 0.0 0.37 10.4 0.0 2.5 2 1 0 2 2 2 0 PHD-finger DUF5588 PF17826.1 CRK14462.1 - 0.044 12.7 0.3 0.076 11.9 0.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5588) Glucodextran_C PF09985.9 CRK14462.1 - 0.2 11.1 0.0 0.2 11.1 0.0 1.6 2 0 0 2 2 2 0 C-terminal binding-module, SLH-like, of glucodextranase zf-C2H2 PF00096.26 CRK14462.1 - 1.4 9.6 5.0 3.1 8.4 0.3 3.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CRK14462.1 - 1.6 9.8 5.9 5.8 8.0 0.7 3.3 2 0 0 2 2 2 0 C2H2-type zinc finger His_Phos_2 PF00328.22 CRK14463.1 - 0.00086 18.8 0.0 0.0016 17.8 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) OFeT_1 PF16955.5 CRK14463.1 - 0.051 13.3 0.0 0.09 12.5 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron uptake permease, iron-lead transporter DUF4342 PF14242.6 CRK14463.1 - 1.3 9.0 3.4 2.9 7.9 3.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4342) RTP1_C1 PF10363.9 CRK14467.1 - 2.3e-24 85.7 1.6 1e-23 83.6 0.1 2.8 3 1 1 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 RTP1_C2 PF10304.9 CRK14467.1 - 1.5e-11 43.8 0.2 3.6e-11 42.5 0.2 1.7 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 2 Cnd1 PF12717.7 CRK14467.1 - 0.096 12.7 0.3 0.33 11.0 0.0 2.0 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Fungal_trans PF04082.18 CRK14481.1 - 1.5e-10 40.6 0.1 6.3e-10 38.5 0.1 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain ABC_tran PF00005.27 CRK14482.1 - 7.7e-68 227.3 0.0 1.5e-33 116.2 0.0 2.3 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 CRK14482.1 - 1.4e-51 175.8 47.1 4.1e-41 141.5 15.5 4.1 2 1 2 4 4 4 4 ABC transporter transmembrane region SMC_N PF02463.19 CRK14482.1 - 1.7e-11 44.0 1.1 0.00033 20.2 0.0 4.1 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CRK14482.1 - 2.9e-09 36.5 0.2 0.0014 18.4 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 CRK14482.1 - 3.3e-09 37.1 0.0 0.00048 20.4 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CRK14482.1 - 7e-08 33.0 2.4 0.0014 19.0 0.3 3.0 2 2 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 CRK14482.1 - 1.6e-07 31.3 0.0 0.023 14.6 0.0 2.7 3 0 0 3 3 2 2 RsgA GTPase AAA_21 PF13304.6 CRK14482.1 - 3.2e-07 30.5 1.4 0.13 12.1 0.2 3.9 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 CRK14482.1 - 1.7e-05 24.5 0.1 0.13 11.8 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.6 CRK14482.1 - 3e-05 24.6 0.2 0.099 13.1 0.1 2.3 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.9 CRK14482.1 - 3.1e-05 23.0 0.5 0.031 13.1 0.0 3.4 4 0 0 4 4 4 1 Predicted ATPase of the ABC class AAA_15 PF13175.6 CRK14482.1 - 6.3e-05 22.9 0.0 0.17 11.5 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 CRK14482.1 - 0.00015 21.5 0.1 0.14 11.8 0.1 3.3 3 1 0 3 3 3 1 AAA domain AAA_28 PF13521.6 CRK14482.1 - 0.00052 20.3 0.1 0.17 12.1 0.1 2.8 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 CRK14482.1 - 0.0006 19.8 0.2 4.6 7.2 0.0 3.7 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA PF00004.29 CRK14482.1 - 0.00084 19.8 0.8 8.9 6.8 0.0 4.1 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 CRK14482.1 - 0.0012 19.1 0.1 2.3 8.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 CRK14482.1 - 0.0027 17.3 0.0 1.7 8.1 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_18 PF13238.6 CRK14482.1 - 0.0034 17.9 0.1 3 8.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 CRK14482.1 - 0.0046 16.3 0.0 2.8 7.2 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin MMR_HSR1 PF01926.23 CRK14482.1 - 0.0051 16.9 0.1 0.78 9.8 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase Rad17 PF03215.15 CRK14482.1 - 0.0089 16.0 0.0 3.2 7.6 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain SbcCD_C PF13558.6 CRK14482.1 - 0.028 14.7 2.2 14 6.0 0.1 3.6 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit NB-ARC PF00931.22 CRK14482.1 - 0.03 13.5 0.1 1.9 7.6 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.22 CRK14482.1 - 0.037 14.4 0.1 5.6 7.4 0.0 2.6 2 0 0 2 2 2 0 RNA helicase SRP54 PF00448.22 CRK14482.1 - 0.062 12.9 0.0 3.2 7.3 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain G-alpha PF00503.20 CRK14482.1 - 0.084 12.0 0.0 8 5.5 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit ATP_bind_1 PF03029.17 CRK14482.1 - 0.12 12.1 0.0 7.7 6.2 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 CRK14482.1 - 0.26 11.0 0.2 11 5.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain RICTOR_N PF14664.6 CRK14483.1 - 1.2e-126 422.7 1.0 2.9e-126 421.4 0.1 2.2 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, N-term Phos_pyr_kin PF08543.12 CRK14483.1 - 2.7e-70 236.5 0.8 5.3e-70 235.6 0.8 1.4 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase DEAD PF00270.29 CRK14483.1 - 1.3e-48 165.1 0.0 6.1e-48 162.9 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase TENA_THI-4 PF03070.16 CRK14483.1 - 1.7e-45 155.4 0.0 1.3e-44 152.6 0.0 2.3 2 0 0 2 2 2 1 TENA/THI-4/PQQC family RICTOR_M PF14666.6 CRK14483.1 - 1.1e-34 118.3 0.3 2.8e-33 113.8 0.0 3.5 4 0 0 4 4 3 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.6 CRK14483.1 - 1.5e-34 118.6 0.2 3.7e-33 114.1 0.0 3.2 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain Helicase_C PF00271.31 CRK14483.1 - 1.7e-31 108.8 0.0 5.3e-31 107.2 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RICTOR_V PF14668.6 CRK14483.1 - 8.8e-30 102.8 0.6 2.8e-27 94.7 0.1 4.3 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.16 CRK14483.1 - 4.2e-16 58.8 10.7 4.2e-16 58.8 10.7 2.4 2 0 0 2 2 2 1 Hr1 repeat ResIII PF04851.15 CRK14483.1 - 0.00019 21.5 0.0 0.00056 20.0 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PfkB PF00294.24 CRK14483.1 - 0.00031 20.2 0.1 0.0017 17.7 0.1 2.1 1 1 0 1 1 1 1 pfkB family carbohydrate kinase THOC7 PF05615.13 CRK14483.1 - 0.012 15.9 4.5 0.041 14.2 4.5 1.9 1 0 0 1 1 1 0 Tho complex subunit 7 HEAT_2 PF13646.6 CRK14483.1 - 0.021 15.2 0.6 4.1 7.9 0.0 3.6 2 0 0 2 2 2 0 HEAT repeats Helicase_C_2 PF13307.6 CRK14483.1 - 0.03 14.5 0.0 0.16 12.1 0.0 2.1 2 0 0 2 2 2 0 Helicase C-terminal domain DUF2443 PF10398.9 CRK14483.1 - 0.047 13.7 3.8 5.1 7.2 0.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2443) UTP25 PF06862.12 CRK14483.1 - 0.092 11.5 0.0 2 7.1 0.0 2.2 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Uds1 PF15456.6 CRK14483.1 - 0.35 11.0 10.5 1.1 9.4 10.5 1.8 1 0 0 1 1 1 0 Up-regulated During Septation Arm PF00514.23 CRK14483.1 - 0.53 10.4 3.1 18 5.5 0.0 4.2 5 0 0 5 5 3 0 Armadillo/beta-catenin-like repeat CENP-K PF11802.8 CRK14483.1 - 0.71 9.4 7.5 2.1 7.9 7.5 1.7 1 0 0 1 1 1 0 Centromere-associated protein K DUF4407 PF14362.6 CRK14483.1 - 8.2 5.7 12.6 1.3 8.3 8.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Uricase PF01014.18 CRK14484.1 - 4.7e-77 256.6 0.3 4.6e-39 133.7 0.2 2.0 2 0 0 2 2 2 2 Uricase Ribosomal_L13 PF00572.18 CRK14485.1 - 6.5e-42 142.7 0.0 8.9e-42 142.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 HMA PF00403.26 CRK14486.1 - 7.4e-13 48.7 0.1 1.3e-12 48.0 0.1 1.4 1 0 0 1 1 1 1 Heavy-metal-associated domain Sod_Cu PF00080.20 CRK14486.1 - 3.3e-12 46.8 0.0 6.2e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) TPR_1 PF00515.28 CRK14487.1 - 1e-16 59.9 1.8 1.7e-08 33.9 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CRK14487.1 - 3e-14 51.9 4.0 2e-06 27.4 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 CRK14487.1 - 8e-11 41.3 0.7 7.1e-06 25.8 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 CRK14487.1 - 2.4e-08 34.1 0.1 0.088 13.5 0.0 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 CRK14487.1 - 4.2e-08 33.4 0.4 2.3e-07 31.0 0.1 2.3 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 CRK14487.1 - 5.1e-08 32.4 0.1 3.9e-06 26.5 0.0 3.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 CRK14487.1 - 4.5e-07 29.5 0.3 1.2e-05 24.9 0.1 3.1 1 1 1 2 2 2 1 TPR repeat TPR_9 PF13371.6 CRK14487.1 - 3.4e-05 23.9 0.0 0.16 12.2 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat PB1 PF00564.24 CRK14487.1 - 4.7e-05 23.3 0.1 8e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 PB1 domain TPR_17 PF13431.6 CRK14487.1 - 0.00018 21.6 0.1 0.27 11.7 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 CRK14487.1 - 0.0011 19.6 0.1 0.0077 16.9 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 CRK14487.1 - 0.013 15.3 0.6 0.18 11.7 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 CRK14487.1 - 0.025 15.4 0.4 0.22 12.4 0.0 2.6 2 1 1 3 3 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 CRK14487.1 - 0.16 12.6 0.0 47 5.0 0.0 3.2 2 1 0 2 2 2 0 Tetratricopeptide repeat tRNA-synt_1c PF00749.21 CRK14488.1 - 1.2e-91 306.8 0.0 1.6e-91 306.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain Ribosomal_L32e PF01655.18 CRK14489.1 - 7.6e-49 164.6 0.3 2e-48 163.3 0.3 1.7 1 0 0 1 1 1 1 Ribosomal protein L32 DnaJ_C PF01556.18 CRK14489.1 - 3.1e-35 121.4 1.4 4.3e-35 121.0 0.1 1.9 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ PF00226.31 CRK14489.1 - 4.7e-23 81.1 1.7 1e-22 80.0 1.7 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CRK14489.1 - 2.9e-14 53.2 18.7 5.2e-14 52.4 18.7 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 CRK14489.1 - 0.009 16.0 12.1 0.22 11.5 1.7 2.6 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 CRK14489.1 - 0.15 12.1 8.0 1.3 9.1 1.6 2.5 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF1356 PF07092.12 CRK14489.1 - 4 6.7 4.4 3 7.0 0.6 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1356) zf-RING_10 PF16685.5 CRK14489.1 - 4.3 7.6 11.3 0.6 10.3 2.1 2.4 1 1 1 2 2 2 0 zinc RING finger of MSL2 TackOD1 PF18551.1 CRK14489.1 - 4.7 6.8 8.5 8.2 6.0 1.9 2.2 1 1 0 2 2 2 0 Thaumarchaeal output domain 1 Peptidase_S41 PF03572.18 CRK14492.1 - 0.00014 21.5 0.0 0.0004 20.0 0.0 1.8 2 0 0 2 2 2 1 Peptidase family S41 ELFV_dehydrog PF00208.21 CRK14494.1 - 6.7e-66 222.5 0.0 1.2e-65 221.7 0.0 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 CRK14494.1 - 1.7e-19 69.0 0.0 2.8e-14 51.7 0.0 2.2 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 CRK14494.1 - 0.0035 17.2 0.0 0.035 14.0 0.0 2.3 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Abhydrolase_2 PF02230.16 CRK14497.1 - 1.7e-14 54.2 0.0 1.4e-08 34.9 0.0 2.6 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 CRK14497.1 - 2.7e-06 27.4 0.2 0.032 14.1 0.2 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CRK14497.1 - 1.1e-05 26.2 5.0 0.0014 19.3 1.3 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 CRK14497.1 - 0.0007 19.1 0.0 0.0033 16.9 0.0 2.0 3 0 0 3 3 3 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 CRK14497.1 - 0.018 14.3 0.1 29 3.8 0.0 3.0 3 0 0 3 3 3 0 Serine aminopeptidase, S33 FSH1 PF03959.13 CRK14497.1 - 0.06 13.0 0.0 0.36 10.5 0.0 2.0 1 1 0 2 2 2 0 Serine hydrolase (FSH1) DLH PF01738.18 CRK14497.1 - 0.11 12.1 0.0 0.24 10.9 0.0 1.5 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 CRK14497.1 - 0.11 12.1 0.3 7.5 6.1 0.0 2.5 1 1 0 3 3 3 0 alpha/beta hydrolase fold GAD-like PF08887.11 CRK14497.1 - 0.18 11.6 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 GAD-like domain LDB19 PF13002.7 CRK14498.1 - 1.4e-58 197.9 0.5 7e-31 107.5 0.1 2.5 2 0 0 2 2 2 2 Arrestin_N terminal like Arrestin_N PF00339.29 CRK14498.1 - 2.7e-09 37.2 0.4 0.0017 18.4 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain GnHR_trans PF12369.8 CRK14498.1 - 0.077 13.8 0.0 18 6.2 0.0 2.5 2 0 0 2 2 2 0 Gonadotropin hormone receptor transmembrane region Glyco_hydro_61 PF03443.14 CRK14499.1 - 1.4e-111 371.3 1.4 6.6e-55 186.2 0.1 2.4 2 0 0 2 2 2 2 Glycosyl hydrolase family 61 Peptidase_S8 PF00082.22 CRK14499.1 - 2.3e-21 76.4 5.1 4.3e-21 75.5 5.1 1.4 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 CRK14499.1 - 9.9e-12 45.4 0.0 1.5e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase inhibitor I9 SH3_3 PF08239.11 CRK14499.1 - 0.049 13.9 3.5 26 5.2 0.1 4.4 3 2 0 3 3 3 0 Bacterial SH3 domain FAD_binding_4 PF01565.23 CRK14500.1 - 1.2e-23 83.4 1.2 2.4e-23 82.4 1.2 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 CRK14500.1 - 0.15 12.2 0.1 0.57 10.3 0.0 2.0 2 0 0 2 2 2 0 Berberine and berberine like Cutinase PF01083.22 CRK14501.1 - 8.4e-49 165.9 0.0 1e-48 165.7 0.0 1.1 1 0 0 1 1 1 1 Cutinase Abhydrolase_2 PF02230.16 CRK14501.1 - 0.02 14.7 0.1 0.028 14.2 0.1 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase VirJ PF06057.11 CRK14501.1 - 0.089 12.7 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) DUF2974 PF11187.8 CRK14501.1 - 0.13 11.8 0.0 0.17 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Cu-oxidase_2 PF07731.14 CRK14502.1 - 7.1e-43 145.6 8.7 7.6e-39 132.6 2.4 3.7 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 CRK14502.1 - 1e-40 139.5 1.0 6.7e-35 120.6 0.0 3.3 3 0 0 3 3 3 3 Multicopper oxidase Cu-oxidase_3 PF07732.15 CRK14502.1 - 1.6e-40 137.8 5.0 5.7e-38 129.6 0.9 2.6 3 0 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.6 CRK14502.1 - 0.012 15.7 0.0 9.8 6.4 0.0 3.1 3 0 0 3 3 3 0 Cupredoxin-like domain DUF5060 PF16586.5 CRK14502.1 - 0.084 13.2 0.2 1.5 9.3 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5060) FTR1 PF03239.14 CRK14503.1 - 6.2e-78 262.1 6.5 7.9e-78 261.7 6.5 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family SLATT_3 PF18184.1 CRK14503.1 - 5.6 7.1 8.1 2.5 8.2 0.6 2.9 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain 3 DUF89 PF01937.19 CRK14507.1 - 9.1e-129 429.4 0.0 1.5e-128 428.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF89 Fungal_trans PF04082.18 CRK14507.1 - 3.6e-12 45.9 0.0 7.6e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK14507.1 - 0.0013 18.8 6.6 0.0013 18.8 6.6 2.5 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 CRK14508.1 - 1.8e-32 112.6 36.5 1.1e-31 110.0 33.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ABC2_membrane_5 PF13346.6 CRK14508.1 - 2.6 7.5 8.4 0.14 11.7 0.2 2.5 2 0 0 2 2 2 0 ABC-2 family transporter protein Methyltransf_2 PF00891.18 CRK14509.1 - 1.9e-23 82.9 0.0 3e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_31 PF13847.6 CRK14509.1 - 0.011 15.5 0.0 0.025 14.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 CRK14509.1 - 0.029 15.1 0.0 0.075 13.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.9 CRK14509.1 - 0.055 13.2 0.0 0.095 12.4 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase Glyco_transf_54 PF04666.13 CRK14510.1 - 1e-07 31.1 0.4 1.2e-06 27.6 0.2 2.4 2 1 0 2 2 2 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region MauE PF07291.11 CRK14510.1 - 0.072 12.8 1.2 0.14 11.9 1.1 1.4 1 1 0 1 1 1 0 Methylamine utilisation protein MauE TGT PF01702.18 CRK14510.1 - 0.084 12.0 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Queuine tRNA-ribosyltransferase EPSP_synthase PF00275.20 CRK14511.1 - 1.2e-130 436.0 0.0 2e-130 435.3 0.0 1.3 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 CRK14511.1 - 5.2e-102 340.5 0.0 8e-102 339.9 0.0 1.3 1 0 0 1 1 1 1 3-dehydroquinate synthase SKI PF01202.22 CRK14511.1 - 7.4e-25 87.9 0.1 2.7e-23 82.8 0.0 2.3 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 CRK14511.1 - 1.2e-19 70.4 0.0 3.1e-19 69.0 0.0 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Fe-ADH_2 PF13685.6 CRK14511.1 - 3.1e-07 30.4 0.1 1.1e-06 28.6 0.1 1.9 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase DHquinase_I PF01487.15 CRK14511.1 - 5.9e-05 23.4 0.0 0.0001 22.6 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase SDH_C PF18317.1 CRK14511.1 - 0.017 14.9 0.7 0.052 13.3 0.7 1.9 1 0 0 1 1 1 0 Shikimate 5'-dehydrogenase C-terminal domain AAA_22 PF13401.6 CRK14511.1 - 0.11 12.8 0.0 0.32 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CRK14511.1 - 0.12 12.8 0.0 0.46 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 CRK14511.1 - 0.17 12.1 0.0 0.47 10.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Lon_C PF05362.13 CRK14516.1 - 9.4e-64 214.7 0.0 1.8e-63 213.8 0.0 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 CRK14516.1 - 4.4e-34 118.2 0.1 1e-33 117.0 0.1 1.7 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 CRK14516.1 - 5.9e-22 78.5 0.0 2e-21 76.8 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.6 CRK14516.1 - 1.4e-07 31.4 0.0 3.6e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.14 CRK14516.1 - 7.8e-07 29.2 0.0 2e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CRK14516.1 - 1.1e-06 28.8 0.1 4.5e-06 26.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_PrkA PF08298.11 CRK14516.1 - 2.5e-05 23.4 0.0 5.1e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain AAA_22 PF13401.6 CRK14516.1 - 2.9e-05 24.4 0.0 0.0005 20.3 0.0 2.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 CRK14516.1 - 5.8e-05 22.9 0.0 0.00056 19.7 0.0 2.6 4 0 0 4 4 4 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CRK14516.1 - 0.00019 21.9 0.1 0.0017 18.8 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 CRK14516.1 - 0.0063 16.6 0.0 0.027 14.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 CRK14516.1 - 0.009 15.8 0.0 0.081 12.7 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_18 PF13238.6 CRK14516.1 - 0.013 16.0 0.4 0.067 13.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 CRK14516.1 - 0.038 13.7 0.1 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 CRK14516.1 - 0.041 13.8 0.3 0.13 12.2 0.0 1.9 2 0 0 2 2 1 0 RsgA GTPase RNA_helicase PF00910.22 CRK14516.1 - 0.042 14.2 0.0 0.14 12.6 0.0 2.0 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.15 CRK14516.1 - 0.057 13.3 0.2 1.3 8.9 0.0 2.6 1 1 1 2 2 2 0 NTPase DNTTIP1_dimer PF18192.1 CRK14516.1 - 0.059 13.7 0.6 1.2 9.6 0.1 3.0 2 1 1 3 3 3 0 DNTTIP1 dimerisation domain AAA_3 PF07726.11 CRK14516.1 - 0.071 13.0 0.0 0.69 9.8 0.0 2.6 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 CRK14516.1 - 0.084 12.4 0.9 0.22 11.0 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region SKI PF01202.22 CRK14516.1 - 0.084 13.0 0.1 0.44 10.7 0.0 2.1 2 0 0 2 2 2 0 Shikimate kinase Cytidylate_kin PF02224.18 CRK14516.1 - 0.15 11.8 1.9 5.2 6.7 0.0 2.7 3 0 0 3 3 3 0 Cytidylate kinase AbrB_C PF18277.1 CRK14516.1 - 0.17 11.5 0.1 1.4 8.6 0.0 2.6 2 0 0 2 2 2 0 AbrB C-terminal domain ClpB_D2-small PF10431.9 CRK14516.1 - 0.24 11.5 5.1 0.11 12.5 0.4 2.6 2 0 0 2 2 2 0 C-terminal, D2-small domain, of ClpB protein ABC_tran PF00005.27 CRK14516.1 - 0.46 11.0 3.6 0.74 10.3 0.0 2.7 3 0 0 3 3 3 0 ABC transporter TPT PF03151.16 CRK14519.1 - 8.8e-20 71.2 18.6 1.1e-19 70.9 18.6 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CRK14519.1 - 0.23 11.6 32.1 0.096 12.9 13.1 2.6 3 0 0 3 3 3 0 EamA-like transporter family UAA PF08449.11 CRK14519.1 - 2.7 7.1 27.4 0.032 13.4 19.9 1.5 2 0 0 2 2 2 0 UAA transporter family IL28A PF15177.6 CRK14520.1 - 0.044 13.6 0.1 0.056 13.3 0.1 1.3 1 1 0 1 1 1 0 Interleukin-28A DnaJ PF00226.31 CRK14522.1 - 5e-11 42.6 0.0 8.6e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain Sugar_tr PF00083.24 CRK14523.1 - 1.1e-17 64.0 9.1 1.6e-17 63.5 9.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK14523.1 - 1.4e-13 50.5 25.0 2.1e-13 49.9 25.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Aconitase_2_N PF06434.13 CRK14523.1 - 0.066 12.8 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Aconitate hydratase 2 N-terminus DUF4611 PF15387.6 CRK14523.1 - 1.1 9.6 12.8 6.8 7.0 1.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) BUD22 PF09073.10 CRK14523.1 - 2.8 7.2 13.3 5.8 6.1 13.3 1.4 1 0 0 1 1 1 0 BUD22 SOG2 PF10428.9 CRK14523.1 - 5.8 6.0 7.6 9.3 5.3 7.6 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein RNA_pol_Rbc25 PF08292.12 CRK14524.1 - 8.5e-33 113.3 2.7 1.3e-31 109.5 2.7 2.1 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 CRK14524.1 - 2.3e-13 50.3 0.0 3.9e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 CRK14524.1 - 0.088 13.2 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 S1 RNA binding domain Pkinase PF00069.25 CRK14535.1 - 3e-17 62.8 0.0 4.1e-17 62.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 CRK14535.1 - 1.2e-07 30.9 0.0 1.7e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 CRK14535.1 - 7.9e-07 28.6 0.0 1e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase EMP24_GP25L PF01105.24 CRK14537.1 - 5.9e-52 176.3 0.0 6.7e-52 176.1 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD USP7_C2 PF14533.6 CRK14539.1 - 4e-73 245.5 6.1 2.9e-71 239.4 0.6 2.9 2 1 0 3 3 3 2 Ubiquitin-specific protease C-terminal USP7_ICP0_bdg PF12436.8 CRK14539.1 - 1.2e-71 240.8 0.2 2.7e-70 236.4 0.1 2.1 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 YukD PF08817.10 CRK14539.1 - 0.078 13.7 0.0 0.28 11.9 0.0 2.0 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukD TFIIA PF03153.13 CRK14563.1 - 0.0066 16.5 12.8 0.0073 16.4 12.8 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SOG2 PF10428.9 CRK14563.1 - 1.6 7.8 14.4 1.8 7.7 14.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF2802 PF10975.8 CRK14563.1 - 1.7 8.8 8.4 3.4 7.9 8.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) Presenilin PF01080.17 CRK14563.1 - 9.6 4.8 7.4 13 4.5 7.4 1.1 1 0 0 1 1 1 0 Presenilin Eisosome1 PF12757.7 CRK14564.1 - 0.049 13.9 3.0 0.13 12.5 3.0 1.7 1 0 0 1 1 1 0 Eisosome protein 1 Apt1 PF10351.9 CRK14564.1 - 0.094 11.6 1.7 0.12 11.2 1.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF1748 PF08520.10 CRK14567.1 - 2e-33 114.1 0.0 2.5e-33 113.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) PK PF00224.21 CRK14568.1 - 1.1e-171 570.4 4.4 1.5e-171 569.9 4.4 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 CRK14568.1 - 8.7e-37 125.9 0.0 2.4e-36 124.5 0.0 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 CRK14568.1 - 0.00012 21.3 0.5 0.00043 19.5 0.2 2.0 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 CRK14568.1 - 0.058 12.4 0.1 0.45 9.4 0.0 2.0 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain Ribosomal_S8e PF01201.22 CRK14570.1 - 5.8e-45 152.8 1.2 6.5e-45 152.7 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e PSP1 PF04468.12 CRK14573.1 - 3.6e-28 97.7 1.4 5.9e-28 97.0 1.4 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Nfu_N PF08712.11 CRK14573.1 - 1.3e-27 95.6 0.0 2.8e-27 94.6 0.0 1.6 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 CRK14573.1 - 2.2e-08 34.1 0.0 3.9e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 NifU-like domain Use1 PF09753.9 CRK14574.1 - 0.021 14.5 0.0 0.028 14.1 0.0 1.4 1 1 0 1 1 1 0 Membrane fusion protein Use1 MRI PF15325.6 CRK14575.1 - 6.8 7.8 8.3 15 6.7 1.2 2.4 2 0 0 2 2 2 0 Modulator of retrovirus infection GATase_2 PF00310.21 CRK14576.1 - 2.8e-177 589.6 0.0 4.4e-177 589.0 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 CRK14576.1 - 2.8e-155 517.0 0.0 4.4e-155 516.4 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 CRK14576.1 - 2.1e-110 368.6 0.0 4.9e-109 364.1 0.0 2.2 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 CRK14576.1 - 6.7e-86 286.7 3.0 1.1e-85 286.1 3.0 1.3 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.6 CRK14576.1 - 1.3e-10 41.1 0.0 3.1e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.14 CRK14576.1 - 1.6e-06 27.6 0.0 1.9e-05 24.0 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMN_dh PF01070.18 CRK14576.1 - 0.023 13.8 0.9 0.17 10.8 0.8 2.3 3 0 0 3 3 3 0 FMN-dependent dehydrogenase MADF_DNA_bdg PF10545.9 CRK14576.1 - 2.9 8.3 4.5 0.98 9.8 0.9 2.0 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like VTC PF09359.10 CRK14577.1 - 1.4e-88 296.9 4.7 1.7e-88 296.6 0.3 2.1 2 0 0 2 2 2 1 VTC domain DUF202 PF02656.15 CRK14577.1 - 2.8e-12 46.9 3.3 2.8e-12 46.9 3.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.19 CRK14577.1 - 2.9e-07 30.8 7.6 0.00016 21.8 0.3 4.6 3 1 2 5 5 5 2 SPX domain Tti2 PF10521.9 CRK14577.1 - 0.26 10.8 0.7 0.59 9.6 0.3 1.7 2 0 0 2 2 2 0 Tti2 family BLOC1_2 PF10046.9 CRK14577.1 - 0.63 10.4 7.2 1.1 9.6 2.4 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SUIM_assoc PF16619.5 CRK14577.1 - 5.9 7.0 8.2 0.66 10.1 0.7 3.0 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Zn_clus PF00172.18 CRK14578.1 - 3.4e-08 33.5 9.5 6.3e-08 32.6 9.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 CRK14578.1 - 3.2e-06 26.2 0.3 5e-06 25.6 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_cc PF11790.8 CRK14579.1 - 2.9e-52 177.6 0.3 3.6e-52 177.3 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core PepSY_2 PF13670.6 CRK14580.1 - 0.23 11.5 1.5 0.44 10.6 1.5 1.5 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain CAP_GLY PF01302.25 CRK14581.1 - 2.9e-22 78.5 1.1 4.2e-22 77.9 1.1 1.2 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 CRK14581.1 - 9.1e-22 77.3 0.0 1.4e-21 76.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.23 CRK14581.1 - 0.00072 19.3 0.0 0.0083 15.9 0.0 2.4 1 1 0 1 1 1 1 Ubiquitin family DUF3932 PF13068.6 CRK14581.1 - 0.18 12.1 0.4 0.29 11.4 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3932) Myb_DNA-binding PF00249.31 CRK14582.1 - 1.9e-13 50.4 2.2 1.6e-10 41.0 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CRK14582.1 - 0.00022 21.4 2.6 0.02 15.1 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain SelP_N PF04592.14 CRK14582.1 - 0.52 9.7 3.5 0.82 9.0 3.5 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Methyltransf_11 PF08241.12 CRK14583.1 - 1e-08 35.7 0.0 2.9e-08 34.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK14583.1 - 7.4e-08 33.0 0.0 1.5e-06 28.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CRK14583.1 - 1.3e-06 28.3 0.0 2.2e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK14583.1 - 3.1e-05 24.6 0.0 0.00012 22.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK14583.1 - 0.0023 17.7 0.0 0.046 13.5 0.1 2.1 2 0 0 2 2 2 1 Methyltransferase domain Nup96 PF12110.8 CRK14583.1 - 0.099 11.7 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Nuclear protein 96 GFO_IDH_MocA PF01408.22 CRK14584.1 - 8.2e-18 65.4 0.1 1.9e-17 64.2 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 CRK14584.1 - 0.0023 18.5 0.1 0.0041 17.8 0.1 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain OpuAC PF04069.12 CRK14584.1 - 0.024 14.2 0.3 34 3.9 0.0 3.5 4 0 0 4 4 4 0 Substrate binding domain of ABC-type glycine betaine transport system Aldo_ket_red PF00248.21 CRK14585.1 - 6.2e-15 55.2 0.0 8.4e-15 54.7 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family FGGY_C PF02782.16 CRK14586.1 - 1.7e-45 155.2 0.5 2.7e-45 154.6 0.5 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain GFO_IDH_MocA PF01408.22 CRK14586.1 - 1.2e-17 64.8 0.0 3.7e-17 63.3 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 CRK14586.1 - 0.0037 17.9 0.1 0.0079 16.8 0.1 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Aldo_ket_red PF00248.21 CRK14587.1 - 3e-07 29.9 0.0 0.0047 16.2 0.0 2.3 2 1 0 2 2 2 2 Aldo/keto reductase family CFIA_Pcf11 PF11526.8 CRK14590.1 - 3.4e-06 27.5 0.1 1e-05 25.9 0.0 1.9 2 0 0 2 2 2 1 Subunit of cleavage factor IA Pcf11 CTD_bind PF04818.13 CRK14590.1 - 0.00023 21.9 0.0 0.00069 20.4 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase II-binding domain. VHS PF00790.19 CRK14590.1 - 0.00048 20.0 0.0 0.0014 18.5 0.0 1.7 1 0 0 1 1 1 1 VHS domain zf-C2H2_4 PF13894.6 CRK14590.1 - 0.1 13.5 3.8 5.4 8.1 0.9 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 CRK14590.1 - 0.14 11.9 0.2 0.29 10.9 0.2 1.5 1 0 0 1 1 1 0 zinc-finger C2H2-type zf-RRN7 PF11781.8 CRK14590.1 - 2.6 7.8 4.8 0.21 11.3 0.2 1.6 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 VHS PF00790.19 CRK14592.1 - 0.00078 19.3 0.0 0.0008 19.3 0.0 1.1 1 0 0 1 1 1 1 VHS domain BCDHK_Adom3 PF10436.9 CRK14592.1 - 0.087 12.7 0.2 0.13 12.1 0.2 1.2 1 1 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase Ribosomal_L15e PF00827.17 CRK14593.1 - 3.8e-10 39.8 0.0 6.8e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal L15 PAP2 PF01569.21 CRK14593.1 - 0.029 14.1 0.1 0.063 13.0 0.1 1.5 1 0 0 1 1 1 0 PAP2 superfamily Cyclin PF08613.11 CRK14594.1 - 2.4e-44 151.5 13.6 9.4e-30 104.1 0.0 3.6 2 1 0 2 2 2 2 Cyclin Cyclin_N PF00134.23 CRK14594.1 - 2e-06 27.6 7.2 0.0016 18.2 0.1 2.7 3 0 0 3 3 3 2 Cyclin, N-terminal domain DUF2274 PF10038.9 CRK14594.1 - 0.081 13.4 0.2 29 5.2 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2274) CompInhib_SCIN PF11546.8 CRK14594.1 - 1.2 9.2 3.0 46 4.1 0.0 3.0 3 0 0 3 3 3 0 Staphylococcal complement inhibitor SCIN DUF2407 PF10302.9 CRK14594.1 - 1.3 9.6 4.0 23 5.6 0.2 2.6 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain Arm PF00514.23 CRK14595.1 - 0.00029 20.8 1.5 11 6.2 0.0 5.6 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 CRK14595.1 - 0.017 15.7 16.2 0.019 15.5 1.0 4.9 6 0 0 6 6 6 0 HEAT-like repeat HEAT PF02985.22 CRK14595.1 - 0.071 13.4 2.6 1.1e+02 3.5 0.1 5.5 4 0 0 4 4 4 0 HEAT repeat HEAT_2 PF13646.6 CRK14595.1 - 0.075 13.4 0.3 0.075 13.4 0.3 4.2 5 0 0 5 5 5 0 HEAT repeats Arm PF00514.23 CRK14596.1 - 6e-09 35.6 4.4 0.45 10.6 0.0 7.3 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 CRK14596.1 - 6.9e-05 23.3 20.6 0.036 14.6 0.8 6.4 8 0 0 8 8 8 3 HEAT-like repeat HEAT PF02985.22 CRK14596.1 - 0.00024 21.1 10.6 14 6.3 0.1 8.0 8 0 0 8 8 8 1 HEAT repeat HEAT_2 PF13646.6 CRK14596.1 - 0.0018 18.6 13.0 0.32 11.4 0.5 5.7 5 1 0 5 5 5 2 HEAT repeats TIMELESS PF04821.14 CRK14596.1 - 0.023 14.0 3.7 5.8 6.1 0.0 3.6 4 0 0 4 4 4 0 Timeless protein Bac_rhodopsin PF01036.18 CRK14597.1 - 4.4e-21 75.5 24.6 6e-21 75.0 24.6 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DER1 PF04511.15 CRK14597.1 - 0.49 10.3 9.2 0.031 14.2 3.4 1.8 2 0 0 2 2 2 0 Der1-like family Spore_III_AE PF09546.10 CRK14597.1 - 2.5 7.2 5.8 10 5.2 5.8 1.9 1 1 0 1 1 1 0 Stage III sporulation protein AE (spore_III_AE) TfuA PF07812.12 CRK14598.1 - 0.17 11.6 0.0 0.17 11.6 0.0 1.2 1 1 0 1 1 1 0 TfuA-like protein Bac_rhodopsin PF01036.18 CRK14599.1 - 3.2e-21 75.9 24.0 4.3e-21 75.5 24.0 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DER1 PF04511.15 CRK14599.1 - 0.0029 17.6 3.3 0.0029 17.6 3.3 1.6 1 1 0 2 2 2 1 Der1-like family Spore_III_AE PF09546.10 CRK14599.1 - 0.36 10.0 6.0 2.7 7.1 6.0 2.0 1 1 0 1 1 1 0 Stage III sporulation protein AE (spore_III_AE) Velvet PF11754.8 CRK14601.1 - 1e-48 166.5 0.1 2.2e-30 106.4 0.0 3.4 2 2 1 3 3 3 2 Velvet factor TIG PF01833.24 CRK14602.1 - 2.5e-08 33.9 0.1 1.2e-07 31.7 0.2 2.2 2 0 0 2 2 2 1 IPT/TIG domain Ank_5 PF13857.6 CRK14602.1 - 2.2e-07 31.0 0.0 5e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CRK14602.1 - 1.3e-06 28.9 0.0 2.8e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CRK14602.1 - 1.3e-06 28.8 0.2 8.1e-05 23.1 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 CRK14602.1 - 4.1e-05 23.8 0.0 0.0035 17.7 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 CRK14602.1 - 0.0019 18.5 0.1 0.024 15.2 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Serglycin PF04360.12 CRK14602.1 - 2.4 8.1 5.4 4.1 7.3 0.2 2.5 2 0 0 2 2 2 0 Serglycin DUF3336 PF11815.8 CRK14603.1 - 5.9e-29 100.6 0.0 7.5e-29 100.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 CRK14603.1 - 1e-09 38.8 0.1 1.6e-09 38.3 0.1 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase Peptidase_S51 PF03575.17 CRK14603.1 - 0.16 11.6 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 Peptidase family S51 Peptidase_M57 PF12388.8 CRK14605.1 - 0.023 14.3 0.2 1.3 8.6 0.0 2.1 1 1 1 2 2 2 0 Dual-action HEIGH metallo-peptidase DUF3810 PF12725.7 CRK14605.1 - 0.04 13.3 0.0 0.049 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Peptidase_M43 PF05572.13 CRK14605.1 - 0.088 12.7 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A SNF PF00209.18 CRK14606.1 - 7.1e-89 298.9 40.2 1.3e-55 189.1 17.2 2.4 2 1 1 3 3 3 2 Sodium:neurotransmitter symporter family ELFV_dehydrog_N PF02812.18 CRK14607.1 - 1.4e-18 67.1 0.0 1.6e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain HMG_box PF00505.19 CRK14609.1 - 8.7e-16 58.1 0.1 1.7e-15 57.2 0.1 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CRK14609.1 - 1.9e-12 47.6 0.1 3.7e-12 46.6 0.1 1.5 1 0 0 1 1 1 1 HMG-box domain SAM_1 PF00536.30 CRK14609.1 - 3.8e-10 40.1 0.0 8.2e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 CRK14609.1 - 6.8e-08 32.5 0.2 4.4e-07 29.9 0.0 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Phage_lysis PF03245.13 CRK14609.1 - 0.059 13.5 0.2 0.13 12.4 0.2 1.5 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein WYL_3 PF18488.1 CRK14609.1 - 0.31 11.4 5.3 0.84 10.1 5.3 1.7 1 0 0 1 1 1 0 WYL domain ParA PF10609.9 CRK14610.1 - 5.5e-94 314.2 0.0 6.5e-94 314.0 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 CRK14610.1 - 1.8e-08 34.5 0.0 4.3e-08 33.3 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 CRK14610.1 - 5.1e-05 22.6 0.5 0.00023 20.4 0.2 2.1 2 1 0 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.6 CRK14610.1 - 0.00015 21.8 0.1 0.0046 16.9 0.1 2.1 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 CRK14610.1 - 0.002 17.5 0.0 0.006 15.9 0.0 1.7 1 1 0 1 1 1 1 ATPase MipZ Fer4_NifH PF00142.18 CRK14610.1 - 0.0025 17.3 0.0 0.26 10.7 0.0 2.2 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.6 CRK14610.1 - 0.0052 16.4 0.1 0.0089 15.6 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_26 PF13500.6 CRK14610.1 - 0.011 15.5 0.0 4.7 7.0 0.1 2.2 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 CRK14610.1 - 0.015 15.2 0.1 0.027 14.4 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_30 PF13604.6 CRK14610.1 - 0.017 14.8 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain CLP1_P PF16575.5 CRK14610.1 - 0.05 13.4 0.0 0.083 12.7 0.0 1.3 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop CBP_BcsQ PF06564.12 CRK14610.1 - 0.051 13.0 0.0 0.33 10.4 0.0 1.9 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ SRP54 PF00448.22 CRK14610.1 - 0.06 13.0 0.0 0.17 11.5 0.0 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain RNA_helicase PF00910.22 CRK14610.1 - 0.079 13.4 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 CRK14610.1 - 0.082 13.3 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain TsaE PF02367.17 CRK14610.1 - 0.15 12.1 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE KAP_NTPase PF07693.14 CRK14610.1 - 0.18 11.0 0.0 0.2 10.8 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain Rad17 PF03215.15 CRK14610.1 - 0.23 11.3 0.0 0.45 10.4 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain Cofilin_ADF PF00241.20 CRK14611.1 - 4e-17 62.1 0.0 7.4e-17 61.3 0.0 1.4 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein ALG3 PF05208.13 CRK14615.1 - 5.5e-101 338.6 11.4 2.2e-100 336.6 11.4 1.8 1 1 0 1 1 1 1 ALG3 protein DAO PF01266.24 CRK14615.1 - 1.5e-15 57.6 0.4 2.5e-15 56.9 0.4 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase MFS_1 PF07690.16 CRK14615.1 - 0.00018 20.5 17.9 0.00018 20.5 17.9 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily N_BRCA1_IG PF16158.5 CRK14633.1 - 1.1e-35 122.4 0.0 2.9e-35 121.0 0.0 1.8 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene ZZ PF00569.17 CRK14633.1 - 1.2e-15 57.0 48.0 6.5e-06 25.9 11.3 3.7 3 1 1 4 4 4 3 Zinc finger, ZZ type Baculo_IE-1 PF05290.11 CRK14633.1 - 0.62 10.0 9.7 0.036 14.0 2.6 2.3 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) Alpha-amylase PF00128.24 CRK14649.1 - 0.00012 21.8 1.7 0.00013 21.6 1.7 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain SNF2_N PF00176.23 CRK14654.1 - 1.2e-37 129.5 0.0 1.8e-37 128.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 CRK14654.1 - 3.6e-24 84.5 0.0 6.1e-24 83.8 0.0 1.4 1 0 0 1 1 1 1 HIRAN domain ResIII PF04851.15 CRK14654.1 - 0.00013 22.0 0.0 0.00037 20.5 0.0 1.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CRK14654.1 - 0.00022 21.1 0.4 0.0004 20.2 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase UBA_4 PF14555.6 CRK14654.1 - 0.013 15.3 0.5 0.031 14.1 0.0 1.9 2 0 0 2 2 2 0 UBA-like domain SQS_PSY PF00494.19 CRK14655.1 - 3.5e-36 125.0 0.5 4.7e-36 124.6 0.5 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase UBA_4 PF14555.6 CRK14656.1 - 5.6e-08 32.5 0.1 7.8e-08 32.0 0.1 1.2 1 0 0 1 1 1 1 UBA-like domain Glyoxalase PF00903.25 CRK14657.1 - 1.1e-07 32.1 0.0 5.7e-07 29.8 0.0 1.8 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 CRK14657.1 - 1.2e-05 25.3 0.0 2.2e-05 24.4 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase-like domain Hanta_nucleocap PF00846.18 CRK14657.1 - 0.0048 15.4 0.0 0.006 15.1 0.0 1.1 1 0 0 1 1 1 1 Hantavirus nucleocapsid protein Glyoxalase_6 PF18029.1 CRK14657.1 - 0.019 15.7 0.0 0.026 15.3 0.0 1.1 1 0 0 1 1 1 0 Glyoxalase-like domain PTCB-BRCT PF12738.7 CRK14658.1 - 1.2e-09 38.0 0.0 1.7e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 CRK14658.1 - 3.6e-09 36.9 0.0 4.7e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 CRK14658.1 - 0.11 13.0 0.0 0.16 12.4 0.0 1.2 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain Pkinase PF00069.25 CRK14660.1 - 2.5e-28 99.2 0.0 5.6e-28 98.0 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK14660.1 - 8.4e-09 35.1 0.1 5.2e-08 32.5 0.1 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Glyco_trans_1_4 PF13692.6 CRK14662.1 - 2.3e-05 24.8 0.0 3.3e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 CRK14662.1 - 0.0052 16.3 0.0 0.0077 15.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 CRK14662.1 - 0.097 13.1 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 Mito_carr PF00153.27 CRK14663.1 - 4.1e-15 55.5 0.1 5.8e-15 55.0 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial carrier protein BKACE PF05853.12 CRK14663.1 - 0.026 13.9 0.5 0.037 13.3 0.5 1.2 1 0 0 1 1 1 0 beta-keto acid cleavage enzyme Zn_clus PF00172.18 CRK14665.1 - 2.5e-07 30.7 11.8 4.1e-07 30.0 11.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 CRK14665.1 - 0.00024 20.0 0.1 0.00079 18.3 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain CAP PF00188.26 CRK14666.1 - 9.9e-18 65.2 1.5 1.7e-17 64.4 1.5 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family RHINO PF15319.6 CRK14666.1 - 0.18 11.9 0.1 0.23 11.4 0.1 1.2 1 0 0 1 1 1 0 RAD9, RAD1, HUS1-interacting nuclear orphan protein Lipase_GDSL_2 PF13472.6 CRK14667.1 - 6e-12 46.3 0.3 7.9e-12 45.9 0.3 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 CRK14667.1 - 3e-05 24.1 0.0 3.7e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase PhageMin_Tail PF10145.9 CRK14667.1 - 0.066 13.1 2.8 0.1 12.5 2.8 1.2 1 0 0 1 1 1 0 Phage-related minor tail protein peroxidase PF00141.23 CRK14668.1 - 2.6e-83 279.2 0.0 1e-43 149.7 0.0 2.3 2 0 0 2 2 2 2 Peroxidase ADH_N PF08240.12 CRK14670.1 - 1e-27 96.2 2.3 2.3e-27 95.1 2.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CRK14670.1 - 5.8e-07 29.5 1.1 0.0012 18.8 0.0 3.3 2 1 1 3 3 3 2 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 CRK14670.1 - 6e-07 29.3 1.6 1.3e-06 28.2 1.6 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N_2 PF13602.6 CRK14670.1 - 0.0075 17.3 0.2 0.033 15.2 0.0 2.2 2 1 0 2 2 2 1 Zinc-binding dehydrogenase Cellulase PF00150.18 CRK14671.1 - 9.8e-34 117.1 0.0 1.4e-33 116.5 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF4038 PF13204.6 CRK14671.1 - 0.0067 16.1 0.0 0.0094 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) CHASE6_C PF17150.4 CRK14671.1 - 0.007 17.0 0.1 0.019 15.7 0.1 1.7 1 0 0 1 1 1 1 C-terminal domain of two-partite extracellular sensor domain Glyco_hydro_42 PF02449.15 CRK14671.1 - 0.076 12.3 0.1 1.4 8.2 0.0 2.4 1 1 0 2 2 2 0 Beta-galactosidase Zn_clus PF00172.18 CRK14672.1 - 1.1e-07 31.8 8.4 2.3e-07 30.8 8.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 CRK14672.1 - 0.00068 18.7 0.2 0.0011 18.1 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 CRK14673.1 - 7.2e-73 246.0 21.5 8.8e-73 245.7 21.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK14673.1 - 4.3e-16 58.8 45.3 2.9e-14 52.8 33.6 2.4 1 1 2 3 3 3 3 Major Facilitator Superfamily F-box-like PF12937.7 CRK14675.1 - 0.012 15.5 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 F-box-like GCR1_C PF12550.8 CRK14676.1 - 1.6e-18 66.8 0.9 3.6e-18 65.6 0.9 1.6 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes DUF1515 PF07439.11 CRK14676.1 - 0.84 9.7 4.1 0.85 9.7 2.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) KfrA_N PF11740.8 CRK14676.1 - 4.9 7.9 9.5 1.5 9.6 1.2 3.3 3 1 1 4 4 4 0 Plasmid replication region DNA-binding N-term TPR_12 PF13424.6 CRK14677.1 - 2e-67 223.5 28.6 5.8e-19 68.2 0.9 6.9 3 1 5 8 8 7 6 Tetratricopeptide repeat TPR_10 PF13374.6 CRK14677.1 - 2.3e-57 189.4 22.8 4.4e-11 42.3 0.2 8.7 9 0 0 9 9 8 7 Tetratricopeptide repeat TPR_8 PF13181.6 CRK14677.1 - 6.3e-23 79.0 13.9 0.0017 18.4 0.0 8.6 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_1 PF00515.28 CRK14677.1 - 3.1e-21 74.2 15.8 0.00023 20.8 0.3 8.0 8 0 0 8 8 7 6 Tetratricopeptide repeat TPR_MalT PF17874.1 CRK14677.1 - 2.8e-19 69.7 10.1 2.3e-14 53.5 5.1 2.5 1 1 1 2 2 2 2 MalT-like TPR region TPR_7 PF13176.6 CRK14677.1 - 9.2e-19 66.0 23.2 0.0025 17.7 0.1 8.8 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_2 PF07719.17 CRK14677.1 - 1.8e-18 65.1 15.0 0.0061 16.6 0.1 8.3 9 0 0 9 9 7 4 Tetratricopeptide repeat TPR_4 PF07721.14 CRK14677.1 - 7.3e-16 57.1 0.0 0.0066 17.0 0.0 7.8 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 CRK14677.1 - 8.2e-13 48.0 9.3 0.41 11.6 0.0 8.1 8 0 0 8 8 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 CRK14677.1 - 1.9e-09 37.2 2.4 2.3 8.8 0.0 6.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 CRK14677.1 - 4.5e-09 36.7 12.1 2.8e-05 24.6 1.7 5.4 2 1 3 5 5 5 3 Tetratricopeptide repeat NB-ARC PF00931.22 CRK14677.1 - 1.4e-08 34.3 0.0 0.0045 16.2 0.0 2.6 2 0 0 2 2 2 2 NB-ARC domain Abhydrolase_6 PF12697.7 CRK14677.1 - 8.2e-07 29.9 2.2 0.005 17.5 0.0 3.1 2 1 0 2 2 2 2 Alpha/beta hydrolase family AAA_16 PF13191.6 CRK14677.1 - 5e-06 27.0 0.0 2.2e-05 24.9 0.0 2.1 2 0 0 2 2 1 1 AAA ATPase domain TPR_16 PF13432.6 CRK14677.1 - 7.9e-06 26.4 9.0 0.0042 17.7 2.1 5.8 4 2 0 4 4 4 1 Tetratricopeptide repeat PPR PF01535.20 CRK14677.1 - 1.6e-05 24.9 0.4 16 6.0 0.0 6.8 7 0 0 7 7 6 0 PPR repeat DUF676 PF05057.14 CRK14677.1 - 1.7e-05 24.4 0.1 0.00015 21.3 0.0 2.1 2 0 0 2 2 2 1 Putative serine esterase (DUF676) DUF2225 PF09986.9 CRK14677.1 - 0.00018 21.3 7.3 0.29 10.8 0.4 3.6 2 1 1 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2225) Cohesin_load PF10345.9 CRK14677.1 - 0.00031 19.4 0.9 0.006 15.1 0.2 2.2 1 1 1 2 2 2 1 Cohesin loading factor PGAP1 PF07819.13 CRK14677.1 - 0.0014 18.4 0.6 0.0026 17.5 0.1 1.7 2 0 0 2 2 1 1 PGAP1-like protein RPN7 PF10602.9 CRK14677.1 - 0.004 16.9 5.2 7.5 6.2 0.1 4.6 2 1 3 5 5 5 0 26S proteasome subunit RPN7 ANAPC3 PF12895.7 CRK14677.1 - 0.005 17.0 1.8 0.092 13.0 0.3 3.6 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 CRK14677.1 - 0.016 15.8 20.5 2.5 8.9 0.1 7.5 8 0 0 8 8 7 0 Tetratricopeptide repeat ATPase_2 PF01637.18 CRK14677.1 - 0.035 14.0 0.0 0.078 12.9 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DnaI_N PF07319.11 CRK14677.1 - 0.043 14.5 0.6 0.14 12.8 0.1 2.1 2 0 0 2 2 1 0 Primosomal protein DnaI N-terminus Synaptobrevin PF00957.21 CRK14677.1 - 0.045 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Synaptobrevin YjeF_N PF03853.15 CRK14677.1 - 0.079 12.8 0.1 0.56 10.1 0.0 2.5 3 0 0 3 3 2 0 YjeF-related protein N-terminus NACHT PF05729.12 CRK14677.1 - 0.097 12.6 0.0 0.54 10.2 0.0 2.3 2 0 0 2 2 2 0 NACHT domain RPN6_N PF18055.1 CRK14677.1 - 0.22 11.9 2.9 5.3 7.4 0.1 3.3 1 1 2 3 3 3 0 26S proteasome regulatory subunit RPN6 N-terminal domain TPR_9 PF13371.6 CRK14677.1 - 0.29 11.3 8.7 14 5.9 0.2 4.5 2 1 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 CRK14677.1 - 5.4 6.8 11.4 48 3.8 0.3 4.9 4 0 0 4 4 4 0 TPR repeat Polyketide_cyc2 PF10604.9 CRK14679.1 - 4.5e-05 23.8 0.8 0.0001 22.6 0.8 1.7 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Fungal_trans PF04082.18 CRK14680.1 - 1.7e-14 53.5 0.0 2.3e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK14680.1 - 4.5e-09 36.3 10.3 7.1e-09 35.6 10.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC1 PF03109.16 CRK14681.1 - 1.3e-22 80.2 0.0 6.5e-13 48.9 0.0 2.4 2 0 0 2 2 2 2 ABC1 family APH PF01636.23 CRK14681.1 - 0.019 14.9 0.0 0.044 13.7 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 CRK14681.1 - 0.033 13.8 0.0 0.24 11.0 0.0 2.0 2 0 0 2 2 2 0 RIO1 family Cyto_heme_lyase PF01265.17 CRK14682.1 - 1.2e-119 399.3 1.0 1.8e-119 398.7 1.0 1.3 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase Oxidored_FMN PF00724.20 CRK14684.1 - 1.8e-44 152.4 0.0 2.5e-44 152.0 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 CRK14684.1 - 1.7e-08 33.9 0.0 9.9e-08 31.4 0.0 2.0 1 1 1 2 2 2 1 Dihydrouridine synthase (Dus) MTHFR PF02219.17 CRK14684.1 - 0.13 11.5 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Methylenetetrahydrofolate reductase HMG_box_2 PF09011.10 CRK14685.1 - 0.00027 21.5 12.9 0.0014 19.2 0.1 3.7 4 0 0 4 4 4 2 HMG-box domain HMG_box PF00505.19 CRK14685.1 - 0.0013 19.1 9.6 0.17 12.3 0.2 2.8 3 0 0 3 3 3 2 HMG (high mobility group) box DUF2406 PF10295.9 CRK14685.1 - 0.045 14.4 0.4 12 6.7 0.1 2.9 2 0 0 2 2 2 0 Uncharacterised protein (DUF2406) H_lectin PF09458.10 CRK14687.1 - 4.1e-56 187.1 0.2 3.9e-19 68.6 0.1 3.5 3 0 0 3 3 3 3 H-type lectin domain Peptidase_M10 PF00413.24 CRK14687.1 - 0.00015 21.6 5.5 0.00038 20.3 3.8 2.3 2 1 0 2 2 2 1 Matrixin Peptidase_M43 PF05572.13 CRK14687.1 - 0.0015 18.5 0.1 0.0028 17.6 0.1 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 CRK14687.1 - 0.0021 18.2 0.1 0.004 17.3 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Astacin PF01400.24 CRK14687.1 - 0.0051 16.4 2.0 0.013 15.1 2.0 1.6 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) Reprolysin_2 PF13574.6 CRK14687.1 - 0.0081 16.1 0.1 0.015 15.2 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.8 CRK14687.1 - 0.0098 15.5 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 1 Dual-action HEIGH metallo-peptidase RE_ApaLI PF09499.10 CRK14687.1 - 0.021 14.5 0.2 0.037 13.7 0.2 1.3 1 0 0 1 1 1 0 ApaLI-like restriction endonuclease Glyco_hydro_115 PF15979.5 CRK14689.1 - 1.9e-127 425.4 0.5 2.7e-127 424.9 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 CRK14689.1 - 2.8e-41 141.2 0.0 4.9e-41 140.4 0.0 1.4 1 0 0 1 1 1 1 Gylcosyl hydrolase family 115 C-terminal domain Chorion_3 PF05387.11 CRK14690.1 - 0.29 10.7 8.8 7.2 6.2 9.1 2.0 2 0 0 2 2 2 0 Chorion family 3 DbpA PF03880.15 CRK14692.1 - 0.022 14.7 0.1 0.047 13.7 0.1 1.6 1 0 0 1 1 1 0 DbpA RNA binding domain SLT_2 PF13406.6 CRK14692.1 - 1 8.6 6.5 0.06 12.6 0.5 1.8 2 0 0 2 2 2 0 Transglycosylase SLT domain MFS_1 PF07690.16 CRK14693.1 - 6e-32 110.9 56.8 1.4e-20 73.5 34.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK14694.1 - 1.1e-61 209.2 23.1 8e-59 199.7 23.1 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK14694.1 - 2.9e-11 42.9 30.3 1.3e-09 37.5 9.6 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 CRK14694.1 - 0.0034 16.3 6.2 0.0034 16.3 6.2 1.6 2 0 0 2 2 2 1 MFS_1 like family Tyrosinase PF00264.20 CRK14695.1 - 1e-41 143.7 2.0 1e-41 143.7 2.0 1.5 2 0 0 2 2 2 1 Common central domain of tyrosinase Ctr PF04145.15 CRK14696.1 - 1e-07 32.6 0.0 1.2e-07 32.5 0.0 1.1 1 0 0 1 1 1 1 Ctr copper transporter family E1-E2_ATPase PF00122.20 CRK14697.1 - 1.8e-16 60.2 0.0 1.8e-16 60.2 0.0 3.2 3 1 1 4 4 4 2 E1-E2 ATPase Hydrolase PF00702.26 CRK14697.1 - 3.5e-11 43.8 2.1 5.8e-10 39.8 1.6 2.7 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Tyosinase_C PF18132.1 CRK14700.1 - 0.024 15.3 0.0 0.029 15.0 0.0 1.1 1 0 0 1 1 1 0 Tyosinase C-terminal domain Dioxygenase_C PF00775.21 CRK14702.1 - 3.7e-08 33.0 0.1 6.3e-08 32.3 0.1 1.4 1 0 0 1 1 1 1 Dioxygenase Na_H_Exchanger PF00999.21 CRK14703.1 - 1.6e-54 185.2 45.7 2.4e-54 184.6 45.7 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Usp PF00582.26 CRK14703.1 - 0.045 14.3 2.5 0.42 11.1 2.5 2.2 1 1 0 1 1 1 0 Universal stress protein family Glyco_hydro_61 PF03443.14 CRK14704.1 - 3.3e-32 112.1 0.0 1.3e-31 110.2 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 CRK14704.1 - 6.5e-13 48.4 11.8 2e-12 46.9 11.8 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain Aminotran_5 PF00266.19 CRK14705.1 - 3.1e-19 69.2 0.0 2.6e-13 49.7 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V ADH_zinc_N PF00107.26 CRK14706.1 - 2.4e-11 43.7 0.0 4.2e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CRK14706.1 - 8.1e-06 25.7 0.0 1.5e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 CRK14706.1 - 0.00012 23.1 0.0 0.00021 22.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 CRK14706.1 - 0.086 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Glu_dehyd_C PF16912.5 CRK14706.1 - 0.13 11.7 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Epimerase PF01370.21 CRK14706.1 - 0.14 11.6 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family RTA1 PF04479.13 CRK14707.1 - 1.7e-65 220.5 12.4 1.7e-65 220.5 12.4 1.5 2 0 0 2 2 2 1 RTA1 like protein Fungal_trans_2 PF11951.8 CRK14708.1 - 1e-15 57.5 0.2 2e-15 56.5 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK14708.1 - 3.3e-09 36.7 12.0 4.9e-09 36.2 12.0 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 CRK14709.1 - 1.3e-100 337.4 30.0 1.6e-100 337.1 30.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK14709.1 - 1.4e-18 67.0 30.5 1.4e-18 67.0 30.5 2.3 1 1 0 2 2 2 1 Major Facilitator Superfamily DUF983 PF06170.12 CRK14709.1 - 0.23 11.9 4.5 0.34 11.4 1.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF983) AAA_16 PF13191.6 CRK14710.1 - 9.5e-09 35.9 0.2 2.8e-08 34.3 0.1 1.9 2 1 0 2 2 2 1 AAA ATPase domain ATPase_2 PF01637.18 CRK14710.1 - 0.001 19.0 0.0 0.0015 18.5 0.0 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea DUF815 PF05673.13 CRK14710.1 - 0.023 13.9 0.0 0.051 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA PF00004.29 CRK14710.1 - 0.027 14.9 0.5 0.27 11.7 0.1 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CRK14710.1 - 0.04 13.9 0.0 0.48 10.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF2859 PF11072.8 CRK14710.1 - 0.093 12.5 0.2 0.16 11.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2859) AAA_7 PF12775.7 CRK14710.1 - 0.098 12.2 0.0 0.23 10.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_29 PF13555.6 CRK14710.1 - 0.15 11.8 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Fungal_trans_2 PF11951.8 CRK14711.1 - 6.3e-10 38.4 0.2 6.9e-10 38.3 0.2 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain DEAD PF00270.29 CRK14712.1 - 2.8e-16 59.8 0.0 1.1e-15 57.8 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 CRK14712.1 - 1.6e-12 47.7 0.0 4.6e-12 46.3 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.16 CRK14712.1 - 0.058 12.8 1.1 0.079 12.4 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein DUF202 PF02656.15 CRK14713.1 - 0.0024 18.3 1.6 0.0043 17.4 1.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) GST_N_2 PF13409.6 CRK14718.1 - 1.4e-11 44.5 0.0 1.6e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 CRK14718.1 - 0.0074 16.7 0.0 0.009 16.4 0.0 1.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain FKBP_C PF00254.28 CRK14720.1 - 8.4e-28 96.5 0.1 1.1e-27 96.1 0.1 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase GMC_oxred_C PF05199.13 CRK14739.1 - 3.1e-31 108.8 0.1 4.9e-31 108.2 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 CRK14739.1 - 1.1e-18 67.6 0.1 1.8e-18 67.0 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Peptidase_S28 PF05577.12 CRK14741.1 - 1e-41 143.2 0.0 1.1e-31 110.1 0.0 2.1 2 0 0 2 2 2 2 Serine carboxypeptidase S28 DUF2920 PF11144.8 CRK14741.1 - 0.061 12.5 0.0 0.094 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Peptidase_M76 PF09768.9 CRK14757.1 - 5.1e-57 192.4 1.3 5.9e-57 192.2 1.3 1.0 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.9 CRK14757.1 - 0.0095 15.8 2.8 0.012 15.5 1.1 1.9 1 1 1 2 2 2 1 SprT-like family Peptidase_M91 PF14891.6 CRK14757.1 - 0.037 14.3 0.3 0.048 14.0 0.3 1.2 1 0 0 1 1 1 0 Effector protein BSP PF04450.12 CRK14757.1 - 0.082 12.7 0.1 0.11 12.3 0.1 1.3 1 1 0 1 1 1 0 Peptidase of plants and bacteria Tox-MPTase2 PF15638.6 CRK14757.1 - 0.13 12.0 0.2 0.17 11.6 0.2 1.3 1 1 0 1 1 1 0 Metallopeptidase toxin 2 Peptidase_M1 PF01433.20 CRK14757.1 - 0.86 9.1 3.5 1.4 8.5 3.5 1.5 1 1 0 1 1 1 0 Peptidase family M1 domain Pkinase PF00069.25 CRK14759.1 - 9.1e-73 244.9 0.0 1.1e-72 244.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK14759.1 - 1.3e-43 149.1 0.0 1.7e-43 148.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CRK14759.1 - 1e-07 31.6 0.0 1.6e-06 27.7 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 CRK14759.1 - 0.00035 20.0 0.1 0.00057 19.3 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CRK14759.1 - 0.011 15.4 0.0 0.036 13.7 0.0 1.8 1 1 1 2 2 2 0 RIO1 family YrbL-PhoP_reg PF10707.9 CRK14759.1 - 0.04 13.4 0.3 0.16 11.5 0.0 1.9 1 1 0 2 2 2 0 PhoP regulatory network protein YrbL FTA2 PF13095.6 CRK14759.1 - 0.057 13.0 0.0 0.18 11.4 0.0 1.7 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 CRK14759.1 - 0.083 12.8 0.1 0.19 11.6 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 CRK14759.1 - 0.11 11.6 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 CRK14759.1 - 0.11 11.4 0.1 0.15 11.0 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain zf-RING_2 PF13639.6 CRK14764.1 - 8.1e-12 45.3 7.8 1.8e-11 44.2 7.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 CRK14764.1 - 1.4e-09 37.5 2.6 2.8e-09 36.5 2.6 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 CRK14764.1 - 1.8e-08 34.1 6.7 3.2e-08 33.3 6.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CRK14764.1 - 2.8e-07 30.7 3.3 2.8e-07 30.7 3.3 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CRK14764.1 - 6.3e-07 29.2 7.3 6.3e-07 29.2 7.3 1.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CRK14764.1 - 1.2e-06 28.3 4.9 2.2e-06 27.5 4.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 CRK14764.1 - 2.6e-06 27.4 1.4 4.2e-06 26.7 1.4 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 CRK14764.1 - 3.3e-05 23.7 4.8 6e-05 22.8 4.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CRK14764.1 - 7.1e-05 22.8 3.8 0.00025 21.0 4.1 1.8 1 1 0 1 1 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 CRK14764.1 - 0.0002 20.9 5.7 0.0006 19.4 5.7 1.8 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 CRK14764.1 - 0.00032 20.5 5.5 0.00074 19.3 5.5 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 PepSY_TM PF03929.16 CRK14764.1 - 0.042 13.5 0.0 0.049 13.3 0.0 1.2 1 0 0 1 1 1 0 PepSY-associated TM region zf-Di19 PF05605.12 CRK14764.1 - 0.051 13.9 2.1 2 8.8 0.3 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C3H2C3 PF17122.5 CRK14764.1 - 0.065 13.3 4.4 0.17 11.9 4.4 1.7 1 1 0 1 1 1 0 Zinc-finger zf-C3HC4_4 PF15227.6 CRK14764.1 - 0.093 12.9 5.0 0.29 11.3 5.0 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 CRK14764.1 - 0.12 12.2 5.0 0.2 11.5 3.7 2.1 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C2H2_3 PF13878.6 CRK14764.1 - 0.12 12.2 1.8 0.51 10.2 0.0 2.4 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO zf-RING_6 PF14835.6 CRK14764.1 - 0.14 12.0 1.2 0.28 11.1 1.2 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein TAP42 PF04177.12 CRK14764.1 - 0.21 10.7 0.0 0.27 10.3 0.0 1.1 1 0 0 1 1 1 0 TAP42-like family DUF4592 PF15262.6 CRK14764.1 - 0.34 11.6 0.1 0.34 11.6 0.1 1.6 2 0 0 2 2 1 0 Domain of unknown function (DUF4592) zf-Nse PF11789.8 CRK14764.1 - 0.35 10.7 2.5 0.57 10.0 2.5 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.7 CRK14764.1 - 0.51 10.5 11.2 0.051 13.7 6.6 1.8 2 0 0 2 2 1 0 RING-variant domain zf-RING-like PF08746.11 CRK14764.1 - 0.78 10.1 4.9 1.5 9.2 4.9 1.5 1 0 0 1 1 1 0 RING-like domain FANCL_C PF11793.8 CRK14764.1 - 1.1 9.5 6.2 6.2 7.1 6.2 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain zinc_ribbon_16 PF17034.5 CRK14764.1 - 1.3 9.2 5.2 3.2 8.0 5.2 1.6 1 1 0 1 1 1 0 Zinc-ribbon like family PHD PF00628.29 CRK14764.1 - 3.7 7.5 7.2 1.9 8.4 4.7 1.9 2 1 0 2 2 2 0 PHD-finger Methyltrn_RNA_3 PF02598.17 CRK14765.1 - 6.9e-99 330.9 0.0 8e-99 330.7 0.0 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase LIAS_N PF16881.5 CRK14766.1 - 1.2e-15 57.9 0.2 2.3e-15 57.0 0.2 1.5 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Pectate_lyase_3 PF12708.7 CRK14766.1 - 1.5e-11 44.5 0.2 1.5e-11 44.5 0.2 1.6 2 0 0 2 2 2 1 Pectate lyase superfamily protein Radical_SAM PF04055.21 CRK14766.1 - 5.2e-07 30.2 0.0 8.9e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily End_N_terminal PF12218.8 CRK14766.1 - 0.011 15.4 0.2 0.023 14.4 0.2 1.5 1 0 0 1 1 1 0 N terminal extension of bacteriophage endosialidase Peptidase_C65 PF10275.9 CRK14771.1 - 1.2e-65 221.4 0.0 1.5e-65 221.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain Ad_cyc_g-alpha PF08509.11 CRK14773.1 - 2.7e-22 78.2 2.0 2.7e-22 78.2 2.0 2.6 2 0 0 2 2 2 1 Adenylate cyclase G-alpha binding domain Guanylate_cyc PF00211.20 CRK14773.1 - 6e-07 29.3 0.0 9e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_8 PF13855.6 CRK14773.1 - 1.6e-06 27.8 10.6 0.00062 19.5 2.7 2.4 1 1 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 CRK14773.1 - 0.028 14.8 11.1 0.067 13.6 0.7 2.9 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CRK14773.1 - 5.2 8.0 9.0 2.3 9.1 0.2 3.6 3 1 0 3 3 3 0 Leucine Rich Repeat Acyl-CoA_dh_M PF02770.19 CRK14774.1 - 0.072 13.3 0.1 0.65 10.2 0.0 2.4 3 0 0 3 3 3 0 Acyl-CoA dehydrogenase, middle domain DEAD PF00270.29 CRK14775.1 - 3e-47 160.6 0.0 5.8e-47 159.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.6 CRK14775.1 - 3.7e-21 75.1 0.0 1.1e-20 73.6 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.31 CRK14775.1 - 9e-21 74.3 0.0 5.1e-20 71.9 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CRK14775.1 - 8.9e-07 29.1 0.0 1.9e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.6 CRK14775.1 - 0.012 15.8 0.0 0.032 14.4 0.0 1.6 1 0 0 1 1 1 0 Helicase C-terminal domain Gar1 PF04410.14 CRK14776.1 - 8.4e-46 155.5 0.2 1.7e-45 154.5 0.2 1.5 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region DUF4266 PF14086.6 CRK14776.1 - 0.031 15.2 5.1 0.13 13.3 5.1 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4266) Spt20 PF12090.8 CRK14776.1 - 1.1 8.8 21.3 3.8 7.1 21.3 1.9 1 0 0 1 1 1 0 Spt20 family SH3_9 PF14604.6 CRK14777.1 - 3.2e-10 39.7 0.0 5.3e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CRK14777.1 - 1.7e-06 27.5 0.0 2.7e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CRK14777.1 - 0.00013 21.6 0.0 0.00022 20.8 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain DUF4448 PF14610.6 CRK14777.1 - 0.026 14.3 0.0 0.055 13.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) DUF5305 PF17231.2 CRK14777.1 - 0.23 10.8 0.0 0.42 10.0 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Fungal_trans PF04082.18 CRK14780.1 - 1.2e-30 106.4 0.0 3.1e-30 105.1 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK14780.1 - 6.3e-09 35.8 7.6 1e-08 35.1 7.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4306 PF14154.6 CRK14780.1 - 0.13 12.4 0.1 0.25 11.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4306) GREB1 PF15782.5 CRK14780.1 - 0.72 6.9 1.9 1 6.4 1.9 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Fungal_trans PF04082.18 CRK14781.1 - 2e-44 151.6 0.0 3.1e-44 151.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fis1_TPR_C PF14853.6 CRK14782.1 - 1e-26 92.8 2.2 1.9e-26 91.9 2.2 1.5 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 CRK14782.1 - 9e-18 63.7 0.1 1.5e-17 63.0 0.1 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 CRK14782.1 - 0.0029 17.6 2.0 0.0054 16.7 2.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 CRK14782.1 - 0.091 13.4 0.2 0.22 12.3 0.2 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Spc24 PF08286.11 CRK14783.1 - 1.1e-35 122.1 0.6 6.1e-34 116.4 0.0 2.2 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 Vps5 PF09325.10 CRK14783.1 - 0.032 13.8 3.0 0.042 13.4 3.0 1.2 1 0 0 1 1 1 0 Vps5 C terminal like FAA_hydro_N_2 PF18288.1 CRK14783.1 - 0.21 12.0 2.3 1 9.8 1.1 2.6 2 1 0 2 2 2 0 Fumarylacetoacetase N-terminal domain 2 V_ATPase_I PF01496.19 CRK14783.1 - 0.23 9.3 1.4 0.26 9.2 1.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CLZ PF16526.5 CRK14783.1 - 0.72 10.3 7.6 0.72 10.2 0.7 2.8 2 2 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels GvpG PF05120.12 CRK14783.1 - 1.2 9.2 5.8 0.42 10.7 2.2 2.0 2 0 0 2 2 2 0 Gas vesicle protein G DUF1690 PF07956.11 CRK14783.1 - 1.5 9.2 7.3 3.2 8.2 7.2 1.6 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) FUSC PF04632.12 CRK14783.1 - 2 6.8 9.6 2.5 6.5 9.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family APG6_N PF17675.1 CRK14783.1 - 3.2 8.3 10.9 6.3 7.3 10.8 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region XhlA PF10779.9 CRK14783.1 - 4 7.7 5.2 2.3 8.5 1.1 2.1 2 0 0 2 2 2 0 Haemolysin XhlA DUF4164 PF13747.6 CRK14783.1 - 4.7 7.5 17.5 7.1 7.0 12.3 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Fungal_trans PF04082.18 CRK14784.1 - 2.3e-25 89.2 0.3 3.5e-25 88.6 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK14784.1 - 2.5e-07 30.7 10.3 6.2e-07 29.4 10.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RNB PF00773.19 CRK14784.1 - 0.059 12.7 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 RNB domain TatD_DNase PF01026.21 CRK14785.1 - 3.8e-28 98.6 0.0 6.8e-28 97.7 0.0 1.4 1 1 0 1 1 1 1 TatD related DNase Babuvirus_MP PF07234.11 CRK14786.1 - 0.15 12.3 0.4 0.18 11.9 0.4 1.2 1 0 0 1 1 1 0 Movement and RNA silencing protein Fungal_trans PF04082.18 CRK14787.1 - 1.4e-25 89.9 0.3 2e-25 89.4 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK14787.1 - 2.4e-07 30.8 10.3 4.4e-07 29.9 10.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RNB PF00773.19 CRK14787.1 - 0.045 13.1 0.0 0.074 12.4 0.0 1.2 1 0 0 1 1 1 0 RNB domain TatD_DNase PF01026.21 CRK14788.1 - 7.1e-30 104.2 0.0 1.2e-29 103.5 0.0 1.3 1 1 0 1 1 1 1 TatD related DNase Nucleo_P87 PF07267.11 CRK14788.1 - 0.44 9.4 2.5 0.67 8.7 2.5 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Pyridox_oxase_2 PF12766.7 CRK14790.1 - 1.6e-21 76.7 0.0 4.5e-21 75.3 0.0 1.7 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase HTH_47 PF16221.5 CRK14790.1 - 0.017 14.7 0.0 9.1 5.9 0.0 2.4 2 0 0 2 2 2 0 winged helix-turn-helix DUF5305 PF17231.2 CRK14790.1 - 0.11 11.9 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Glyco_transf_5 PF08323.11 CRK14790.1 - 0.17 11.5 0.1 22 4.6 0.0 2.2 2 0 0 2 2 2 0 Starch synthase catalytic domain Baculo_VP91_N PF08475.10 CRK14790.1 - 0.17 11.5 0.1 0.3 10.8 0.1 1.3 1 0 0 1 1 1 0 Viral capsid protein 91 N-terminal DUF1180 PF06679.12 CRK14790.1 - 1.4 9.3 0.0 1.4 9.3 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1180) RRXRR PF14239.6 CRK14790.1 - 1.7 8.5 9.7 3 7.7 9.7 1.3 1 0 0 1 1 1 0 RRXRR protein DcpS PF05652.12 CRK14792.1 - 2.5e-34 118.2 0.0 4.6e-34 117.4 0.0 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.8 CRK14792.1 - 1.9e-31 108.9 0.1 3.6e-31 108.0 0.1 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding GILT PF03227.16 CRK14793.1 - 1.7e-17 63.6 0.0 2.7e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Hexokinase_2 PF03727.16 CRK14794.1 - 7.2e-49 166.4 0.0 9.4e-49 166.0 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 CRK14794.1 - 1.3e-45 155.8 0.0 1.8e-45 155.3 0.0 1.2 1 0 0 1 1 1 1 Hexokinase TPR_12 PF13424.6 CRK14795.1 - 3e-10 40.2 8.6 0.0016 18.7 0.1 3.8 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CRK14795.1 - 8.7e-08 31.7 6.2 1.3 9.3 0.1 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 CRK14795.1 - 4.6e-06 26.2 2.6 1.9 8.5 0.1 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat Ank_4 PF13637.6 CRK14795.1 - 0.036 14.6 0.0 0.12 13.0 0.0 1.9 1 0 0 1 1 1 0 Ankyrin repeats (many copies) TPR_19 PF14559.6 CRK14795.1 - 0.12 13.0 8.8 0.49 10.9 1.2 3.3 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 CRK14795.1 - 0.37 11.5 5.7 1.1e+02 3.8 0.1 5.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 CRK14795.1 - 0.39 11.1 1.3 84 3.8 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 CRK14795.1 - 1.5 9.5 12.6 1.1 9.9 1.2 4.5 5 2 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 CRK14795.1 - 3 8.7 5.9 67 4.5 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Exo5 PF09810.9 CRK14796.1 - 4.2e-139 464.1 0.0 5e-139 463.9 0.0 1.1 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.7 CRK14796.1 - 0.00019 21.4 0.2 0.75 9.7 0.2 2.9 2 1 0 2 2 2 2 PD-(D/E)XK nuclease superfamily DUF2196 PF09962.9 CRK14797.1 - 1.1e-22 79.7 2.8 1.6e-22 79.2 2.8 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2196) NPP1 PF05630.11 CRK14798.1 - 1.9e-43 148.9 4.4 6.9e-43 147.1 4.4 1.7 1 1 0 1 1 1 1 Necrosis inducing protein (NPP1) MFS_1 PF07690.16 CRK14799.1 - 5.4e-21 74.9 37.0 1.1e-19 70.6 34.1 2.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK14799.1 - 6.8e-09 35.1 4.6 6.8e-09 35.1 4.6 2.7 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 CRK14799.1 - 2.6e-05 22.9 1.4 2.6e-05 22.9 1.4 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 CRK14800.1 - 3.8e-31 108.3 28.2 4.7e-31 108.0 28.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily ABC2_membrane PF01061.24 CRK14802.1 - 4.4e-72 241.9 60.0 1.7e-42 145.2 24.2 4.7 4 1 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 CRK14802.1 - 8e-38 130.0 0.1 2.9e-18 66.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 CRK14802.1 - 7.7e-34 115.5 15.0 1.5e-30 105.0 0.0 3.6 4 0 0 4 4 2 2 CDR ABC transporter ABC_trans_N PF14510.6 CRK14802.1 - 3.4e-19 69.2 0.1 9e-19 67.9 0.1 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 CRK14802.1 - 4.3e-06 27.2 0.4 0.00072 20.0 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 CRK14802.1 - 3.5e-05 23.5 0.1 0.019 14.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 CRK14802.1 - 6e-05 23.0 0.2 0.01 15.8 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 CRK14802.1 - 6.9e-05 23.0 0.2 0.012 15.8 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CRK14802.1 - 0.00011 22.7 0.1 0.0043 17.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CRK14802.1 - 0.00038 20.1 0.9 0.047 13.4 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.19 CRK14802.1 - 0.0022 17.6 1.1 0.052 13.1 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 CRK14802.1 - 0.0024 18.1 1.3 1.7 8.9 0.2 2.8 2 1 0 2 2 2 2 AAA domain AAA_30 PF13604.6 CRK14802.1 - 0.0042 16.8 0.1 0.62 9.7 0.1 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 CRK14802.1 - 0.006 16.5 0.6 2 8.3 0.1 2.6 2 0 0 2 2 2 1 NACHT domain AAA_21 PF13304.6 CRK14802.1 - 0.0081 16.0 0.0 1.1 8.9 0.0 2.8 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system dNK PF01712.19 CRK14802.1 - 0.022 14.6 0.0 0.24 11.2 0.0 2.1 2 0 0 2 2 2 0 Deoxynucleoside kinase MMR_HSR1 PF01926.23 CRK14802.1 - 0.026 14.6 0.1 7.5 6.7 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase Ploopntkinase3 PF18751.1 CRK14802.1 - 0.055 13.4 0.3 0.52 10.2 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 SMC_N PF02463.19 CRK14802.1 - 0.058 12.8 0.1 1.6 8.1 0.0 2.9 2 2 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_17 PF13207.6 CRK14802.1 - 0.083 13.3 0.8 1.7 9.0 0.0 2.9 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CRK14802.1 - 0.12 12.8 0.1 32 5.0 0.0 2.8 2 0 0 2 2 2 0 RNA helicase ABC2_membrane_3 PF12698.7 CRK14802.1 - 0.15 11.1 47.8 0.019 14.1 15.6 3.3 2 1 0 3 3 2 0 ABC-2 family transporter protein AAA_23 PF13476.6 CRK14802.1 - 0.29 11.6 1.0 0.64 10.5 0.0 2.0 3 0 0 3 3 1 0 AAA domain WW PF00397.26 CRK14803.1 - 4.5e-14 52.2 3.5 9.5e-14 51.2 3.5 1.6 1 0 0 1 1 1 1 WW domain DUF2076 PF09849.9 CRK14803.1 - 5.8e-06 26.5 16.2 5.8e-06 26.5 16.2 2.3 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2076) NAD_binding_1 PF00175.21 CRK14804.1 - 2.1e-26 92.7 0.0 3e-26 92.2 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 CRK14804.1 - 4.1e-08 33.5 0.0 0.00094 19.3 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_6 PF00970.24 CRK14804.1 - 2.9e-05 24.3 0.0 0.00022 21.5 0.0 2.3 2 1 1 3 3 3 1 Oxidoreductase FAD-binding domain MFS_1 PF07690.16 CRK14805.1 - 3.5e-36 124.9 62.9 2e-33 115.8 41.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_M35 PF02102.15 CRK14806.1 - 2.1e-76 257.2 14.1 2.5e-76 256.9 14.1 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 CRK14806.1 - 3e-39 134.8 6.1 3e-39 134.8 6.1 1.5 2 0 0 2 2 2 1 Lysine-specific metallo-endopeptidase muHD PF10291.9 CRK14807.1 - 4.2e-69 232.9 0.0 6.7e-69 232.2 0.0 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.23 CRK14807.1 - 1.6e-05 25.1 0.0 1.6e-05 25.1 0.0 2.4 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Laminin_II PF06009.12 CRK14807.1 - 0.043 13.8 0.7 0.16 11.9 0.4 2.1 1 1 0 1 1 1 0 Laminin Domain II ABC2_membrane PF01061.24 CRK14810.1 - 1e-78 263.5 68.7 6e-43 146.7 23.0 3.0 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 CRK14810.1 - 3.5e-33 115.0 0.0 2.2e-16 60.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 CRK14810.1 - 5.9e-31 106.2 10.7 3e-28 97.5 0.1 3.0 3 0 0 3 3 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 CRK14810.1 - 2.8e-12 46.4 43.3 3.4e-07 29.7 12.5 2.7 2 1 0 2 2 2 2 ABC-2 family transporter protein ABC_trans_N PF14510.6 CRK14810.1 - 7.6e-12 45.7 0.1 2.7e-11 43.9 0.1 2.0 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_21 PF13304.6 CRK14810.1 - 4.2e-06 26.8 0.0 0.024 14.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 CRK14810.1 - 8.8e-06 26.2 0.2 0.0021 18.4 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 CRK14810.1 - 1.4e-05 25.1 0.0 3e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_33 PF13671.6 CRK14810.1 - 4.4e-05 23.7 0.0 0.027 14.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CRK14810.1 - 4.8e-05 23.9 0.0 0.00062 20.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 CRK14810.1 - 6.4e-05 22.6 0.1 0.013 15.1 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CRK14810.1 - 0.00016 21.9 0.0 0.023 15.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CRK14810.1 - 0.00026 20.6 0.0 0.021 14.6 0.0 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_17 PF13207.6 CRK14810.1 - 0.00066 20.1 0.0 0.043 14.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 CRK14810.1 - 0.00092 19.8 0.0 0.017 15.6 0.0 2.7 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 CRK14810.1 - 0.00096 19.1 0.0 0.11 12.4 0.0 2.5 2 0 0 2 2 2 1 NACHT domain cobW PF02492.19 CRK14810.1 - 0.0017 17.9 0.1 0.25 10.9 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 CRK14810.1 - 0.0026 18.0 1.5 0.0084 16.4 0.1 2.6 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 CRK14810.1 - 0.0032 17.5 0.0 0.19 11.8 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase TsaE PF02367.17 CRK14810.1 - 0.015 15.3 0.1 0.31 11.0 0.1 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 CRK14810.1 - 0.016 15.7 2.7 1.3 9.5 0.0 3.1 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 CRK14810.1 - 0.017 15.5 0.0 4.6 7.7 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_30 PF13604.6 CRK14810.1 - 0.024 14.4 0.1 0.49 10.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 CRK14810.1 - 0.043 14.2 0.0 15 5.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain dNK PF01712.19 CRK14810.1 - 0.058 13.2 0.0 0.22 11.4 0.0 1.9 2 0 0 2 2 2 0 Deoxynucleoside kinase FtsK_SpoIIIE PF01580.18 CRK14810.1 - 0.079 12.3 0.0 7.7 5.8 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family T2SSE PF00437.20 CRK14810.1 - 0.08 12.0 0.0 2.6 7.1 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_24 PF13479.6 CRK14810.1 - 0.11 12.2 0.0 1 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain Pantoate_ligase PF02569.15 CRK14810.1 - 0.12 11.5 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Pantoate-beta-alanine ligase DUF1631 PF07793.11 CRK14810.1 - 0.17 10.3 9.5 0.3 9.5 9.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) GET2 PF08690.10 CRK14810.1 - 0.45 10.1 4.3 1.3 8.7 4.3 1.7 1 0 0 1 1 1 0 GET complex subunit GET2 Ysc84 PF04366.12 CRK14812.1 - 4.8e-38 129.8 0.3 6.8e-38 129.3 0.3 1.2 1 0 0 1 1 1 1 Las17-binding protein actin regulator Synaptobrevin PF00957.21 CRK14813.1 - 0.037 13.8 1.0 0.49 10.2 0.1 2.0 1 1 1 2 2 2 0 Synaptobrevin Phage_holin_2_4 PF16082.5 CRK14813.1 - 0.084 12.6 0.3 0.19 11.5 0.1 1.6 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like ArfGap PF01412.18 CRK14814.1 - 5.5e-39 132.9 0.8 8.2e-39 132.3 0.8 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf partial_CstF PF15861.5 CRK14814.1 - 0.034 13.9 0.1 0.069 12.9 0.1 1.4 1 0 0 1 1 1 0 Partial cleavage stimulation factor domain WD40 PF00400.32 CRK14816.1 - 3.8e-17 62.3 0.5 0.0012 19.6 0.0 4.4 4 0 0 4 4 4 4 WD domain, G-beta repeat F-box-like PF12937.7 CRK14816.1 - 8.3e-14 51.2 1.8 2e-12 46.8 0.4 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CRK14816.1 - 4.8e-07 29.5 0.3 1.7e-06 27.7 0.1 2.0 2 0 0 2 2 2 1 F-box domain ANAPC4_WD40 PF12894.7 CRK14816.1 - 0.0027 17.9 0.1 0.016 15.5 0.0 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain F-box_4 PF15966.5 CRK14816.1 - 0.026 14.4 0.3 0.41 10.5 0.0 2.6 3 0 0 3 3 3 0 F-box MgtE_N PF03448.17 CRK14816.1 - 0.097 13.3 0.0 0.23 12.1 0.0 1.5 1 0 0 1 1 1 0 MgtE intracellular N domain CDC24 PF06395.11 CRK14817.1 - 5.3e-16 58.6 0.0 1.1e-15 57.6 0.0 1.5 1 0 0 1 1 1 1 CDC24 Calponin Aminotran_1_2 PF00155.21 CRK14854.1 - 2.5e-86 290.1 0.0 2.8e-86 290.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II HAUS4 PF14735.6 CRK14855.1 - 0.00074 19.3 0.0 0.0013 18.5 0.0 1.4 1 1 0 1 1 1 1 HAUS augmin-like complex subunit 4 DUF5082 PF16888.5 CRK14855.1 - 0.082 13.2 0.0 2.5 8.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Glyco_hydro_76 PF03663.14 CRK14856.1 - 1.2e-88 298.2 10.4 1.7e-88 297.6 10.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 ABC2_membrane PF01061.24 CRK14856.1 - 1.8e-45 154.9 20.8 1.8e-45 154.9 20.8 2.0 2 0 0 2 2 2 1 ABC-2 type transporter PDR_CDR PF06422.12 CRK14856.1 - 4.2e-34 116.3 2.4 7.3e-34 115.6 0.0 2.5 2 0 0 2 2 2 1 CDR ABC transporter DUF2070 PF09843.9 CRK14856.1 - 9.8 4.3 14.5 17 3.6 14.5 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Metallophos PF00149.28 CRK14857.1 - 1.3e-06 29.1 0.1 2.4e-06 28.2 0.1 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CRK14857.1 - 0.0024 18.1 0.0 0.0032 17.7 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Anoctamin PF04547.12 CRK14858.1 - 1.5e-91 307.5 14.8 1.8e-91 307.2 14.8 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel SNF5 PF04855.12 CRK14859.1 - 2.6e-66 223.8 0.1 4.2e-65 219.9 0.1 2.2 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 ChAPs PF09295.10 CRK14863.1 - 7.8e-09 35.0 0.1 8.5e-09 34.9 0.1 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) DUF3391 PF11871.8 CRK14864.1 - 0.18 12.3 0.0 0.18 12.3 0.0 5.8 3 1 0 3 3 3 0 Domain of unknown function (DUF3391) DSS1_SEM1 PF05160.13 CRK14865.1 - 1.2e-23 82.9 14.9 1.7e-23 82.5 14.9 1.2 1 0 0 1 1 1 1 DSS1/SEM1 family ArfGap PF01412.18 CRK14865.1 - 0.14 12.3 1.0 0.19 11.8 1.0 1.2 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf FumaraseC_C PF10415.9 CRK14866.1 - 0.12 12.8 0.4 0.54 10.7 0.1 2.3 2 0 0 2 2 2 0 Fumarase C C-terminus Tachystatin_B PF11478.8 CRK14867.1 - 0.13 12.3 3.9 0.27 11.2 3.9 1.5 1 0 0 1 1 1 0 Antimicrobial chitin binding protein tachystatin B Cg6151-P PF10233.9 CRK14868.1 - 2.7e-43 146.8 16.5 3.2e-43 146.6 16.5 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P DUF308 PF03729.13 CRK14868.1 - 0.013 15.8 3.6 0.013 15.8 3.6 2.5 2 1 0 2 2 2 0 Short repeat of unknown function (DUF308) CitMHS PF03600.16 CRK14868.1 - 0.04 13.1 11.1 0.043 13.0 11.1 1.0 1 0 0 1 1 1 0 Citrate transporter Cytochrom_B558a PF05038.13 CRK14868.1 - 0.96 9.0 7.6 3.4 7.2 7.0 2.1 1 1 1 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit Cation_ATPase_C PF00689.21 CRK14868.1 - 1.7 8.3 13.6 1.1 8.9 9.9 2.0 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus Aim21 PF11489.8 CRK14869.1 - 4.4e-181 604.4 83.1 4.4e-181 604.4 83.1 2.5 3 0 0 3 3 3 1 Altered inheritance of mitochondria protein 21 Glyco_hydro_49N PF17433.2 CRK14872.1 - 3.5e-61 206.1 0.3 6.5e-61 205.3 0.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 49 N-terminal Ig-like domain Peptidase_M22 PF00814.25 CRK14872.1 - 5.5e-40 137.8 0.0 5.9e-20 72.1 0.0 3.2 2 2 0 2 2 2 2 Glycoprotease family Glyco_hydro_49 PF03718.13 CRK14872.1 - 4.7e-14 52.4 0.2 1.6e-13 50.7 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 49 B_solenoid_dext PF18841.1 CRK14872.1 - 4.5e-12 46.0 2.1 1.9e-11 44.1 2.1 2.2 1 1 0 1 1 1 1 Beta solenoid repeat from Dextranase IPU_b_solenoid PF18783.1 CRK14872.1 - 1.1e-08 35.0 3.5 2.4e-08 33.9 3.5 1.7 1 0 0 1 1 1 1 Isopullulanase beta-solenoid repeat Proteasome PF00227.26 CRK14873.1 - 9.1e-47 159.0 0.3 1.1e-46 158.8 0.3 1.1 1 0 0 1 1 1 1 Proteasome subunit Complex1_LYR_2 PF13233.6 CRK14874.1 - 2.5e-18 66.6 0.0 3.6e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 CRK14874.1 - 1.5e-10 41.0 0.1 2.4e-10 40.3 0.1 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 CRK14874.1 - 0.019 15.6 0.0 0.028 15.0 0.0 1.3 1 0 0 1 1 1 0 Complex1_LYR-like OB_NTP_bind PF07717.16 CRK14875.1 - 5.6e-11 42.6 0.2 2.1e-10 40.8 0.1 1.9 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Complex1_LYR_2 PF13233.6 CRK14876.1 - 2.2e-18 66.8 0.0 3.1e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 CRK14876.1 - 1.5e-10 41.0 0.1 2.4e-10 40.3 0.1 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 CRK14876.1 - 0.019 15.6 0.0 0.028 15.0 0.0 1.3 1 0 0 1 1 1 0 Complex1_LYR-like HA2 PF04408.23 CRK14878.1 - 1.5e-18 67.0 0.0 1.5e-18 67.0 0.0 3.0 3 1 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CRK14878.1 - 7.2e-12 45.6 0.0 1.8e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CRK14878.1 - 1.2e-06 28.4 0.9 9.6e-06 25.5 0.0 2.8 3 1 0 3 3 3 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CRK14878.1 - 0.00015 22.1 0.0 0.001 19.4 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 CRK14878.1 - 0.00098 19.3 2.4 1.2 9.3 0.1 3.6 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 CRK14878.1 - 0.0022 17.7 0.1 0.066 13.0 0.0 2.9 3 0 0 3 3 3 1 P-loop containing region of AAA domain ABC_tran PF00005.27 CRK14878.1 - 0.016 15.7 0.0 0.016 15.7 0.0 3.8 3 1 0 3 3 3 0 ABC transporter AAA_24 PF13479.6 CRK14878.1 - 0.023 14.4 0.2 6.4 6.4 0.0 3.7 4 1 0 4 4 4 0 AAA domain AAA_16 PF13191.6 CRK14878.1 - 0.062 13.7 0.1 0.99 9.8 0.0 2.9 3 0 0 3 3 3 0 AAA ATPase domain RsgA_GTPase PF03193.16 CRK14878.1 - 0.069 13.0 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_5 PF07728.14 CRK14878.1 - 0.14 12.1 1.1 6 6.9 0.0 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 CRK14878.1 - 1.2 9.6 7.6 4 7.9 0.0 3.3 3 0 0 3 3 3 0 AAA domain FPN1 PF06963.12 CRK14879.1 - 6.7e-106 354.5 15.4 7.6e-106 354.3 15.4 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) GTP_EFTU PF00009.27 CRK14880.1 - 2.5e-09 37.0 0.0 7.3e-09 35.4 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 CRK14880.1 - 0.078 12.7 0.5 11 5.7 0.2 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_29 PF13555.6 CRK14880.1 - 0.09 12.5 0.9 0.2 11.4 0.9 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 CRK14880.1 - 0.094 13.2 0.0 0.21 12.1 0.0 1.6 1 0 0 1 1 1 0 ABC transporter T2SSE PF00437.20 CRK14880.1 - 0.095 11.7 0.5 0.19 10.8 0.5 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Rab5ip PF07019.12 CRK14881.1 - 2.1e-27 95.5 6.3 2.5e-27 95.3 6.3 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) Alpha-amylase PF00128.24 CRK14882.1 - 9.1e-108 360.8 0.0 1.1e-107 360.5 0.0 1.0 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 CRK14882.1 - 0.11 11.5 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain COesterase PF00135.28 CRK14883.1 - 4.8e-71 240.2 0.0 1.5e-65 222.0 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 CRK14883.1 - 1.7e-07 31.3 0.5 1.4e-06 28.4 0.5 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold HET PF06985.11 CRK14884.1 - 6.6e-05 23.3 2.8 0.00011 22.6 0.0 2.7 2 1 1 3 3 3 1 Heterokaryon incompatibility protein (HET) Fungal_trans PF04082.18 CRK14885.1 - 1.3e-09 37.5 0.1 2e-09 36.9 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain AMP-binding PF00501.28 CRK14886.1 - 7.9e-73 245.4 0.0 1e-72 245.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CRK14886.1 - 2.2e-11 44.5 0.5 4.3e-11 43.6 0.5 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.13 CRK14886.1 - 0.17 10.7 0.0 0.27 10.0 0.0 1.2 1 0 0 1 1 1 0 GH3 auxin-responsive promoter Acyl-CoA_dh_1 PF00441.24 CRK14887.1 - 1.3e-15 57.9 1.0 1.9e-13 50.9 0.7 3.0 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 CRK14887.1 - 1.8e-12 47.2 0.1 9.3e-12 45.0 0.1 2.3 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain AidB_N PF18158.1 CRK14887.1 - 6.2e-12 45.7 0.0 1e-11 45.0 0.0 1.4 1 0 0 1 1 1 1 Adaptive response protein AidB N-terminal domain Vezatin PF12632.7 CRK14888.1 - 5.2e-66 222.9 0.1 6.8e-66 222.5 0.1 1.1 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes DUF4231 PF14015.6 CRK14888.1 - 0.064 13.7 3.2 0.21 12.1 1.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Ribosomal_S30 PF04758.14 CRK14889.1 - 1.4e-28 98.9 5.5 1.5e-28 98.8 5.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Phos_pyr_kin PF08543.12 CRK14890.1 - 6.9e-11 42.0 0.0 1.2e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 CRK14890.1 - 3.3e-07 29.9 1.4 5.7e-07 29.1 0.0 2.0 3 0 0 3 3 3 1 pfkB family carbohydrate kinase CENP-K PF11802.8 CRK14891.1 - 3.7e-12 46.4 4.1 0.00026 20.7 0.0 2.4 2 1 0 2 2 2 2 Centromere-associated protein K Taxilin PF09728.9 CRK14891.1 - 0.0012 18.1 8.1 0.0012 18.1 8.1 2.0 2 0 0 2 2 2 1 Myosin-like coiled-coil protein DUF445 PF04286.12 CRK14891.1 - 0.021 14.6 4.3 0.056 13.2 2.6 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF445) SlyX PF04102.12 CRK14891.1 - 0.074 13.7 1.7 0.074 13.7 1.7 3.9 3 1 2 5 5 5 0 SlyX Toprim_2 PF13155.6 CRK14891.1 - 0.21 12.0 4.5 1.6 9.2 4.5 2.3 1 1 0 1 1 1 0 Toprim-like DUF948 PF06103.11 CRK14891.1 - 0.3 11.4 4.1 21 5.4 0.1 3.6 2 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Syntaxin_2 PF14523.6 CRK14891.1 - 0.4 11.1 9.7 0.65 10.4 4.7 3.0 2 1 0 2 2 2 0 Syntaxin-like protein SLATT_5 PF18160.1 CRK14891.1 - 0.4 10.0 3.7 2.8 7.2 2.0 2.2 1 1 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 DUF4337 PF14235.6 CRK14891.1 - 0.41 10.7 2.9 14 5.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) DUF2115 PF09888.9 CRK14891.1 - 0.62 10.6 3.0 0.45 11.0 1.2 1.6 2 0 0 2 2 1 0 Uncharacterized protein conserved in archaea (DUF2115) OmpH PF03938.14 CRK14891.1 - 0.65 10.3 17.4 5.5 7.3 0.3 3.1 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) Laminin_II PF06009.12 CRK14891.1 - 0.79 9.7 9.4 1.1 9.3 0.1 3.6 3 1 1 4 4 4 0 Laminin Domain II DUF2570 PF10828.8 CRK14891.1 - 1.2 9.0 9.0 0.11 12.3 2.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2570) Ran-binding PF05508.11 CRK14891.1 - 1.5 7.8 7.8 0.62 9.0 3.7 1.9 1 1 1 2 2 2 0 RanGTP-binding protein BST2 PF16716.5 CRK14891.1 - 1.9 9.1 22.8 0.082 13.5 4.2 3.4 4 0 0 4 4 3 0 Bone marrow stromal antigen 2 FlxA PF14282.6 CRK14891.1 - 2 8.4 15.0 4 7.5 3.3 2.6 2 0 0 2 2 2 0 FlxA-like protein FOXP-CC PF16159.5 CRK14891.1 - 2.6 8.7 10.3 0.81 10.4 0.3 3.3 2 1 1 3 3 3 0 FOXP coiled-coil domain TBCA PF02970.16 CRK14891.1 - 3 8.2 8.8 5.7 7.3 2.3 3.5 2 1 1 3 3 3 0 Tubulin binding cofactor A FapA PF03961.13 CRK14891.1 - 3 6.3 6.4 22 3.5 3.4 2.2 2 0 0 2 2 2 0 Flagellar Assembly Protein A CDC37_N PF03234.14 CRK14891.1 - 3.4 8.6 9.9 0.52 11.2 5.3 2.0 3 0 0 3 3 1 0 Cdc37 N terminal kinase binding Exo5 PF09810.9 CRK14891.1 - 3.6 7.0 7.1 7.5 5.9 7.1 1.6 1 1 0 1 1 1 0 Exonuclease V - a 5' deoxyribonuclease ABC_tran_CTD PF16326.5 CRK14891.1 - 6.9 7.0 18.2 11 6.4 6.6 3.5 3 0 0 3 3 3 0 ABC transporter C-terminal domain FAM76 PF16046.5 CRK14891.1 - 8.9 5.6 7.3 16 4.7 4.2 2.0 2 0 0 2 2 2 0 FAM76 protein KH_1 PF00013.29 CRK14892.1 - 8.9e-42 140.8 6.9 1.5e-17 63.1 0.6 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 CRK14892.1 - 8.9e-13 47.9 3.6 0.0037 17.1 0.3 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 CRK14892.1 - 3.6e-06 26.8 3.1 0.36 10.7 0.1 4.0 4 0 0 4 4 4 2 KH domain MOEP19 PF16005.5 CRK14892.1 - 0.00015 21.7 0.0 0.044 13.8 0.0 2.8 3 0 0 3 3 3 1 KH-like RNA-binding domain KH_5 PF13184.6 CRK14892.1 - 0.0022 18.0 9.2 0.38 10.9 0.4 3.4 3 0 0 3 3 3 2 NusA-like KH domain GPI-anchored PF10342.9 CRK14894.1 - 8.2e-18 65.0 0.1 8.2e-18 65.0 0.1 2.4 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Hamartin PF04388.12 CRK14894.1 - 9.4 4.8 8.1 12 4.4 8.1 1.0 1 0 0 1 1 1 0 Hamartin protein Glyco_hydro_31 PF01055.26 CRK14896.1 - 3.4e-73 247.3 1.2 5.1e-62 210.5 0.4 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 CRK14896.1 - 1.3e-35 122.0 0.0 4.8e-35 120.2 0.0 1.9 2 0 0 2 2 2 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 CRK14896.1 - 1.7e-15 57.0 1.4 1.7e-15 57.0 1.4 1.8 2 0 0 2 2 2 1 Galactose mutarotase-like PhageMin_Tail PF10145.9 CRK14896.1 - 0.1 12.4 0.1 2.9 7.7 0.0 2.2 2 0 0 2 2 2 0 Phage-related minor tail protein Ceramidase_alk PF04734.13 CRK14897.1 - 1e-212 707.3 0.0 1.2e-212 707.1 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 CRK14897.1 - 1.9e-57 193.8 0.0 2.9e-57 193.2 0.0 1.3 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal HLH PF00010.26 CRK14898.1 - 9.2e-12 44.7 0.6 2e-11 43.7 0.6 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF2014 PF09427.10 CRK14898.1 - 6.9e-06 25.6 0.0 1.3e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) CcmD PF04995.14 CRK14899.1 - 0.00042 20.3 0.0 0.0009 19.3 0.0 1.5 1 0 0 1 1 1 1 Heme exporter protein D (CcmD) TMEM154 PF15102.6 CRK14899.1 - 0.16 11.9 0.1 0.16 11.9 0.1 1.8 2 0 0 2 2 2 0 TMEM154 protein family UvrD_C PF13361.6 CRK14901.1 - 4.7e-64 217.0 0.2 1.7e-63 215.1 0.1 1.8 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 CRK14901.1 - 2.5e-62 211.2 0.0 2.5e-60 204.6 0.0 2.3 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 CRK14901.1 - 1.4e-30 106.5 0.0 3.3e-30 105.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 CRK14901.1 - 1.9e-14 53.2 0.2 6.1e-14 51.6 0.0 2.0 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 CRK14901.1 - 5.5e-08 32.7 0.2 0.0012 18.6 0.1 2.5 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 CRK14901.1 - 3.1e-05 23.8 0.0 0.47 10.1 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.6 CRK14901.1 - 0.00032 20.4 0.0 0.0021 17.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF445 PF04286.12 CRK14901.1 - 0.065 13.0 0.4 0.14 12.0 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF445) HD-ZIP_N PF04618.12 CRK14901.1 - 0.071 13.6 0.1 0.24 12.0 0.1 1.9 1 0 0 1 1 1 0 HD-ZIP protein N terminus Pyr_redox_2 PF07992.14 CRK14903.1 - 9.5e-42 143.2 0.8 1.4e-41 142.6 0.8 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR PF01077.22 CRK14903.1 - 3.9e-19 68.7 0.0 7.4e-19 67.8 0.0 1.5 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox PF00070.27 CRK14903.1 - 1e-16 61.3 0.4 1e-16 61.3 0.4 2.8 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.15 CRK14903.1 - 8.2e-15 54.9 13.1 2.3e-12 47.0 5.5 3.0 3 0 0 3 3 3 2 BFD-like [2Fe-2S] binding domain Rieske PF00355.26 CRK14903.1 - 1.9e-13 50.2 0.2 2.8e-12 46.4 0.0 2.8 2 1 0 2 2 2 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 CRK14903.1 - 9.6e-13 48.0 0.0 8.8e-05 22.4 0.0 2.9 2 1 0 3 3 3 2 Rieske-like [2Fe-2S] domain NIR_SIR_ferr PF03460.17 CRK14903.1 - 3.9e-08 33.0 0.0 9.8e-08 31.7 0.0 1.7 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rubredoxin_C PF18267.1 CRK14903.1 - 5.4e-05 23.0 0.0 1.1 9.2 0.0 4.3 5 0 0 5 5 5 2 Rubredoxin NAD+ reductase C-terminal domain Pyr_redox_3 PF13738.6 CRK14903.1 - 0.0038 16.5 0.0 0.0081 15.5 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 CRK14903.1 - 0.012 15.0 3.3 1.3 8.3 0.1 2.6 2 1 0 3 3 3 0 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 CRK14903.1 - 0.022 14.8 0.9 2.6 8.0 0.0 3.5 3 1 1 4 4 4 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 CRK14903.1 - 0.37 10.1 3.6 4.6 6.5 0.0 2.5 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain DHBP_synthase PF00926.19 CRK14905.1 - 9.3e-121 400.4 0.2 1.3e-74 249.9 0.0 2.1 2 0 0 2 2 2 2 3,4-dihydroxy-2-butanone 4-phosphate synthase DUF3572 PF12096.8 CRK14905.1 - 0.036 14.3 0.1 1.2 9.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3572) DUF5539 PF17693.1 CRK14905.1 - 1.2 8.7 8.2 1.1 8.8 0.4 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5539) DAO PF01266.24 CRK14906.1 - 1e-34 120.7 0.0 1.4e-34 120.3 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CRK14906.1 - 7.1e-06 25.5 0.0 0.0016 17.8 0.0 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 CRK14906.1 - 2.1e-05 23.6 0.2 0.15 10.9 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_9 PF13454.6 CRK14906.1 - 3.8e-05 23.7 0.6 0.43 10.6 0.0 3.0 3 0 0 3 3 3 2 FAD-NAD(P)-binding K_oxygenase PF13434.6 CRK14906.1 - 0.0008 18.7 0.1 0.0018 17.5 0.0 1.6 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) GMC_oxred_N PF00732.19 CRK14906.1 - 0.0023 17.4 0.0 0.11 11.8 0.0 2.4 2 0 0 2 2 2 1 GMC oxidoreductase HI0933_like PF03486.14 CRK14906.1 - 0.0049 15.6 0.1 0.65 8.6 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein TrkA_N PF02254.18 CRK14906.1 - 0.0056 16.9 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain DUF538 PF04398.12 CRK14906.1 - 0.0058 17.1 0.0 0.24 11.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF538 NAD_binding_8 PF13450.6 CRK14906.1 - 0.0067 16.6 0.0 0.015 15.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 CRK14906.1 - 0.011 16.3 0.0 0.021 15.4 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CRK14906.1 - 0.019 14.2 0.0 0.037 13.3 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GATA PF00320.27 CRK14908.1 - 5.3e-16 57.9 3.5 8.2e-16 57.3 3.5 1.3 1 0 0 1 1 1 1 GATA zinc finger MR_MLE_C PF13378.6 CRK14943.1 - 1.4e-42 145.7 0.0 1.9e-42 145.3 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 CRK14943.1 - 2.1e-09 37.6 0.0 3.6e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Fungal_trans PF04082.18 CRK14944.1 - 2.3e-06 26.9 0.1 3.9e-06 26.1 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DLH PF01738.18 CRK14971.1 - 1.9e-07 30.9 0.1 2.3e-07 30.6 0.1 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family ACPS PF01648.20 CRK14973.1 - 2.7e-09 37.1 0.0 6.2e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily adh_short PF00106.25 CRK14990.1 - 1.1e-23 83.7 0.1 1.4e-23 83.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK14990.1 - 2.7e-13 50.0 0.1 3.2e-13 49.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK14990.1 - 8.3e-05 22.6 0.0 0.00011 22.2 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 CRK14990.1 - 0.003 17.5 0.2 0.0052 16.7 0.2 1.4 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 CRK14990.1 - 0.0037 16.7 0.1 0.0043 16.5 0.1 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3HCDH_N PF02737.18 CRK14990.1 - 0.0068 16.3 0.1 0.01 15.8 0.0 1.3 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyco_tran_WecB PF03808.13 CRK14990.1 - 0.021 14.8 0.0 0.029 14.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family NAD_binding_2 PF03446.15 CRK14990.1 - 0.021 15.0 0.0 0.049 13.8 0.0 1.5 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Sacchrp_dh_NADP PF03435.18 CRK14990.1 - 0.037 14.3 0.2 0.063 13.5 0.2 1.4 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 CRK14990.1 - 0.039 13.1 0.1 0.045 12.9 0.1 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein F420_oxidored PF03807.17 CRK14990.1 - 0.074 13.6 0.0 0.13 12.9 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Glyco_hydro_72 PF03198.14 CRK15006.1 - 1.3e-114 382.8 2.9 1.4e-114 382.6 2.9 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 CRK15006.1 - 4e-08 33.0 0.3 2.5e-06 27.1 0.3 2.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 CRK15006.1 - 2.2e-05 23.7 0.1 6e-05 22.3 0.1 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Peptidase_M22 PF00814.25 CRK15041.1 - 3.1e-42 145.1 0.0 1.5e-20 74.0 0.0 3.4 2 2 0 2 2 2 2 Glycoprotease family Glyco_hydro_49N PF17433.2 CRK15043.1 - 3.5e-60 202.9 0.5 6.5e-60 202.0 0.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 49 N-terminal Ig-like domain Glyco_hydro_49 PF03718.13 CRK15043.1 - 5.7e-14 52.1 0.1 2.5e-13 50.0 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 49 B_solenoid_dext PF18841.1 CRK15043.1 - 2.9e-11 43.5 3.2 2.9e-11 43.5 3.2 2.7 2 1 0 2 2 2 1 Beta solenoid repeat from Dextranase IPU_b_solenoid PF18783.1 CRK15043.1 - 1.6e-09 37.6 3.3 3.9e-09 36.4 3.3 1.7 1 0 0 1 1 1 1 Isopullulanase beta-solenoid repeat Sugar_tr PF00083.24 CRK15045.1 - 1.9e-59 201.7 24.4 2.4e-57 194.8 22.5 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CRK15045.1 - 3.4e-11 42.7 54.7 1.7e-10 40.4 28.0 2.3 2 1 1 3 3 3 2 Major Facilitator Superfamily RPE65 PF03055.15 CRK15046.1 - 2.5e-102 343.5 0.0 2.9e-102 343.2 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Fungal_trans PF04082.18 CRK15047.1 - 4.3e-17 62.0 0.2 5.9e-17 61.6 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK15047.1 - 0.00016 21.7 7.4 0.00033 20.7 7.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ArabFuran-catal PF09206.11 CRK15048.1 - 3.2e-143 476.8 12.4 4.4e-143 476.3 12.4 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic AbfB PF05270.13 CRK15048.1 - 8.2e-53 178.2 1.2 1.4e-52 177.4 1.2 1.4 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) domain Bac_rhamnosid6H PF17389.2 CRK15050.1 - 4.6e-121 404.2 0.5 6.5e-121 403.7 0.5 1.2 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Glyco_transf_34 PF05637.12 CRK15050.1 - 2.2e-58 197.8 0.1 3e-58 197.4 0.1 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Bac_rhamnosid_N PF08531.10 CRK15050.1 - 2.3e-58 196.8 0.0 5.4e-58 195.6 0.0 1.7 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid PF05592.11 CRK15050.1 - 3.6e-25 87.9 0.0 6.9e-25 87.0 0.0 1.4 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Transglut_core PF01841.19 CRK15051.1 - 2.8e-11 43.8 0.1 5.3e-11 43.0 0.1 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily Gln_amidase PF15644.6 CRK15051.1 - 0.057 14.4 0.1 0.27 12.3 0.0 2.2 1 1 0 1 1 1 0 Papain fold toxin 1, glutamine deamidase MFS_1 PF07690.16 CRK15052.1 - 2.6e-49 168.1 57.4 3.2e-48 164.5 36.6 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK15052.1 - 5.6e-08 32.1 22.1 2e-07 30.2 21.8 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 CRK15052.1 - 2.4e-07 30.4 6.3 2.4e-07 30.4 6.3 1.7 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 CRK15052.1 - 0.12 10.6 1.9 0.49 8.6 1.9 2.0 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family TPPK_C PF12555.8 CRK15052.1 - 4.9 7.3 7.6 0.16 12.0 0.5 2.3 2 1 1 3 3 3 0 Thiamine pyrophosphokinase C terminal Glycos_transf_4 PF00953.21 CRK15053.1 - 2.7e-13 50.2 16.3 4.5e-11 43.0 2.7 3.1 3 1 1 4 4 4 2 Glycosyl transferase family 4 PHD PF00628.29 CRK15055.1 - 1.1e-07 31.6 10.0 2.4e-07 30.6 10.0 1.6 1 0 0 1 1 1 1 PHD-finger SET PF00856.28 CRK15055.1 - 0.00027 21.4 0.0 0.0044 17.4 0.0 2.8 2 0 0 2 2 2 1 SET domain E1_DerP2_DerF2 PF02221.15 CRK15056.1 - 1.6e-28 99.8 0.1 1.9e-28 99.5 0.1 1.1 1 0 0 1 1 1 1 ML domain Alph_Pro_TM PF09608.10 CRK15056.1 - 0.011 15.5 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) ATP-synt_F PF01990.17 CRK15057.1 - 4.3e-34 116.7 0.1 5e-34 116.5 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DUF4820 PF16091.5 CRK15058.1 - 0.019 14.3 4.1 0.037 13.4 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4820) Aconitase PF00330.20 CRK15060.1 - 1.6e-128 429.6 0.0 7.4e-104 348.3 0.0 2.2 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 CRK15060.1 - 1.3e-31 109.7 0.0 2.5e-31 108.7 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain OPT PF03169.15 CRK15061.1 - 3.9e-187 623.6 36.4 4e-151 504.7 36.2 2.1 1 1 1 2 2 2 2 OPT oligopeptide transporter protein Methyltransf_16 PF10294.9 CRK15061.1 - 2.8e-10 40.2 0.0 0.00067 19.4 0.0 2.3 2 0 0 2 2 2 2 Lysine methyltransferase Inositol_P PF00459.25 CRK15064.1 - 4.6e-65 219.8 0.0 8.6e-65 218.9 0.0 1.4 1 0 0 1 1 1 1 Inositol monophosphatase family MFS_1 PF07690.16 CRK15064.1 - 3.6e-32 111.7 26.6 1.8e-27 96.2 8.4 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK15064.1 - 5.9e-08 32.0 3.0 5.9e-08 32.0 3.0 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 CRK15064.1 - 0.003 16.5 1.7 0.003 16.5 1.7 2.4 2 0 0 2 2 2 1 MFS_1 like family TPR_2 PF07719.17 CRK15064.1 - 0.0089 16.1 2.1 3 8.2 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 CRK15064.1 - 0.034 14.7 0.7 0.16 12.5 0.3 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat HrpB2 PF09487.10 CRK15064.1 - 3.2 8.2 8.7 5.6 7.4 0.4 4.1 4 0 0 4 4 4 0 Bacterial type III secretion protein (HrpB2) PC-Esterase PF13839.6 CRK15065.1 - 0.0048 16.7 0.0 0.0077 16.0 0.0 1.3 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Phage_holin_3_6 PF07332.11 CRK15066.1 - 0.16 12.0 1.6 0.27 11.3 1.6 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III E1-E2_ATPase PF00122.20 CRK15067.1 - 1.4e-49 168.0 2.5 1.4e-49 168.0 2.5 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 CRK15067.1 - 1.7e-24 87.3 4.9 3.1e-24 86.4 4.9 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 CRK15067.1 - 2.3e-08 34.4 0.2 7.7e-08 32.7 0.2 2.0 1 0 0 1 1 1 1 Heavy-metal-associated domain HAD PF12710.7 CRK15067.1 - 0.0062 17.0 0.2 0.065 13.6 0.1 2.3 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CRK15067.1 - 0.4 10.4 1.2 2.9 7.6 0.0 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF1192 PF06698.11 CRK15068.1 - 0.066 13.3 0.1 0.14 12.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Sec62 PF03839.16 CRK15069.1 - 1.4e-69 233.9 2.1 2.5e-69 233.1 2.1 1.3 1 0 0 1 1 1 1 Translocation protein Sec62 Bromodomain PF00439.25 CRK15069.1 - 2.3e-15 56.4 0.1 5.6e-15 55.2 0.1 1.6 1 0 0 1 1 1 1 Bromodomain BTB PF00651.31 CRK15069.1 - 1.6e-05 25.1 0.0 4.6e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Corona_M PF01635.18 CRK15069.1 - 9.6 5.4 7.1 16 4.7 7.1 1.2 1 0 0 1 1 1 0 Coronavirus M matrix/glycoprotein Sugar_tr PF00083.24 CRK15070.1 - 5.5e-106 355.1 25.5 7.9e-106 354.6 25.5 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK15070.1 - 5.1e-25 88.1 25.0 5.1e-25 88.1 25.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 CRK15070.1 - 4.7e-10 39.3 3.2 9.4e-10 38.3 3.2 1.5 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 CRK15070.1 - 0.00019 20.0 5.7 0.021 13.2 0.5 2.2 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 CRK15070.1 - 0.00031 19.7 8.2 0.46 9.3 0.1 3.4 2 1 1 3 3 3 3 MFS_1 like family PDR_assoc PF08370.11 CRK15070.1 - 0.028 14.2 8.3 0.087 12.6 1.5 3.2 3 0 0 3 3 3 0 Plant PDR ABC transporter associated Dpy19 PF10034.9 CRK15070.1 - 0.054 11.7 2.0 0.094 10.9 2.0 1.3 1 0 0 1 1 1 0 Q-cell neuroblast polarisation LapA_dom PF06305.11 CRK15070.1 - 1.1 9.1 7.9 1.2 9.0 0.1 3.9 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain ABC_tran PF00005.27 CRK15071.1 - 9e-47 159.0 1.9 3.4e-22 79.4 0.0 3.6 3 1 0 3 3 2 2 ABC transporter AAA_21 PF13304.6 CRK15071.1 - 5.5e-12 46.1 1.5 0.00028 20.8 0.0 4.2 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CRK15071.1 - 3.6e-08 33.0 0.1 0.0002 21.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 CRK15071.1 - 4.8e-08 32.7 3.8 0.031 13.7 0.0 4.7 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 CRK15071.1 - 6.7e-07 29.4 0.1 0.085 12.9 0.0 3.3 3 0 0 3 3 2 2 50S ribosome-binding GTPase ABC_tran_Xtn PF12848.7 CRK15071.1 - 7.8e-06 25.8 4.1 7.8e-06 25.8 4.1 2.3 2 0 0 2 2 1 1 ABC transporter AAA_28 PF13521.6 CRK15071.1 - 8.3e-06 26.1 0.2 0.0038 17.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 CRK15071.1 - 8.5e-06 25.8 2.0 0.022 14.6 0.0 3.1 3 0 0 3 3 3 2 RsgA GTPase DUF87 PF01935.17 CRK15071.1 - 6.2e-05 23.2 4.2 0.27 11.3 0.0 3.3 3 0 0 3 3 3 2 Helicase HerA, central domain AAA_23 PF13476.6 CRK15071.1 - 7.3e-05 23.4 10.6 0.014 15.9 0.0 3.7 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.6 CRK15071.1 - 9.1e-05 23.0 0.1 0.67 10.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 CRK15071.1 - 0.0001 22.6 0.3 0.35 11.1 0.0 3.3 3 1 0 3 3 3 2 AAA domain AAA_33 PF13671.6 CRK15071.1 - 0.00019 21.6 0.4 1.2 9.2 0.0 3.2 3 0 0 3 3 3 2 AAA domain NACHT PF05729.12 CRK15071.1 - 0.00028 20.8 0.1 0.041 13.8 0.0 2.7 2 0 0 2 2 2 1 NACHT domain MeaB PF03308.16 CRK15071.1 - 0.00043 19.4 0.6 0.55 9.2 0.1 2.5 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 CRK15071.1 - 0.00047 19.9 1.2 0.78 9.4 0.1 3.3 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 CRK15071.1 - 0.0029 18.0 6.5 0.23 11.8 1.3 3.0 2 2 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.12 CRK15071.1 - 0.0054 16.0 0.1 1.5 8.0 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin RNA_helicase PF00910.22 CRK15071.1 - 0.0073 16.7 0.0 1.3 9.5 0.0 2.5 2 0 0 2 2 2 1 RNA helicase KapB PF08810.10 CRK15071.1 - 0.0093 16.1 0.5 0.21 11.8 0.1 2.5 2 0 0 2 2 2 1 Kinase associated protein B AAA_13 PF13166.6 CRK15071.1 - 0.014 14.1 5.3 1.1 7.8 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.6 CRK15071.1 - 0.018 14.8 0.0 0.018 14.8 0.0 3.3 3 1 1 4 4 4 0 AAA ATPase domain TsaE PF02367.17 CRK15071.1 - 0.019 14.9 0.4 2 8.4 0.1 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 CRK15071.1 - 0.02 15.3 0.1 1 9.8 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 CRK15071.1 - 0.028 14.3 0.1 2 8.3 0.0 3.0 3 0 0 3 3 3 0 NTPase Thymidylate_kin PF02223.17 CRK15071.1 - 0.043 13.5 3.8 1.1 9.0 0.0 2.8 3 0 0 3 3 2 0 Thymidylate kinase AAA_27 PF13514.6 CRK15071.1 - 0.05 13.2 6.9 0.082 12.5 0.0 3.2 4 0 0 4 4 3 0 AAA domain Arf PF00025.21 CRK15071.1 - 0.052 13.0 0.4 1.3 8.4 0.1 2.5 2 0 0 2 2 2 0 ADP-ribosylation factor family ATP-synt_ab PF00006.25 CRK15071.1 - 0.052 13.2 0.4 9.3 5.8 0.1 2.4 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_7 PF12775.7 CRK15071.1 - 0.066 12.7 0.1 0.75 9.3 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_24 PF13479.6 CRK15071.1 - 0.074 12.8 0.1 3 7.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 CRK15071.1 - 0.1 11.8 6.1 0.8 8.8 0.0 3.3 3 0 0 3 3 3 0 NB-ARC domain Ploopntkinase1 PF18748.1 CRK15071.1 - 0.12 11.9 0.0 12 5.4 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase1 Roc PF08477.13 CRK15071.1 - 0.12 12.6 0.0 17 5.6 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 CRK15071.1 - 0.14 12.2 2.6 1.7 8.7 0.0 2.9 3 1 0 3 3 2 0 Dynamin family AAA_14 PF13173.6 CRK15071.1 - 0.21 11.6 4.4 3.2 7.8 0.0 3.7 5 0 0 5 5 3 0 AAA domain AAA_17 PF13207.6 CRK15071.1 - 2.9 8.3 9.7 3.8 7.9 0.0 3.9 4 1 1 5 5 4 0 AAA domain Nuc_N PF14448.6 CRK15071.1 - 5.8 6.8 5.5 1.1 9.2 0.3 2.4 3 0 0 3 3 2 0 Nuclease N terminal DAGK_cat PF00781.24 CRK15072.1 - 2.9e-06 26.9 0.0 5.9e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Keratin_2_head PF16208.5 CRK15072.1 - 3 7.9 21.2 1.1 9.4 14.9 2.4 2 0 0 2 2 2 0 Keratin type II head Ribosomal_L12_N PF16320.5 CRK15072.1 - 4.1 7.2 4.8 64 3.4 0.0 2.6 2 0 0 2 2 2 0 Ribosomal protein L7/L12 dimerisation domain TRM PF02005.16 CRK15073.1 - 1.8e-101 340.1 0.0 5.6e-89 299.0 0.0 2.1 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase CDH-cyt PF16010.5 CRK15073.1 - 0.061 13.0 0.2 0.11 12.1 0.2 1.3 1 0 0 1 1 1 0 Cytochrome domain of cellobiose dehydrogenase Methyltr_RsmB-F PF01189.17 CRK15073.1 - 0.1 12.2 0.0 1.5 8.4 0.0 2.3 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F zf-CCHC_5 PF14787.6 CRK15073.1 - 1.3 8.8 5.7 1.4 8.7 0.9 2.4 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger SLATT_fungal PF18142.1 CRK15074.1 - 4.6e-26 91.2 0.2 5.8e-26 90.8 0.2 1.1 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain SDA1 PF05285.12 CRK15076.1 - 3.2 7.1 5.1 4 6.8 5.1 1.1 1 0 0 1 1 1 0 SDA1 HMG_box PF00505.19 CRK15077.1 - 0.00081 19.8 3.6 0.0027 18.1 3.6 2.0 1 0 0 1 1 1 1 HMG (high mobility group) box CALCOCO1 PF07888.11 CRK15077.1 - 0.0026 16.7 11.0 0.0026 16.7 11.0 2.1 2 0 0 2 2 2 1 Calcium binding and coiled-coil domain (CALCOCO1) like Golgin_A5 PF09787.9 CRK15077.1 - 0.0045 16.5 12.7 0.062 12.8 10.4 2.3 2 0 0 2 2 2 1 Golgin subfamily A member 5 MAD PF05557.13 CRK15077.1 - 0.013 14.0 11.0 0.015 13.7 7.6 2.0 2 0 0 2 2 2 0 Mitotic checkpoint protein DUF2524 PF10732.9 CRK15077.1 - 0.05 13.9 3.8 8.7 6.7 0.8 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2524) TSC22 PF01166.18 CRK15077.1 - 0.059 13.7 0.5 3.4 8.0 0.0 2.9 2 0 0 2 2 2 0 TSC-22/dip/bun family Fib_alpha PF08702.10 CRK15077.1 - 0.077 13.2 6.4 0.077 13.2 4.7 1.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Fez1 PF06818.15 CRK15077.1 - 0.078 13.4 10.1 0.2 12.1 10.1 1.7 1 0 0 1 1 1 0 Fez1 Sugarporin_N PF11471.8 CRK15077.1 - 0.11 12.4 5.9 0.86 9.6 2.4 2.7 1 1 1 2 2 2 0 Maltoporin periplasmic N-terminal extension BBP1_C PF15272.6 CRK15077.1 - 0.22 11.3 5.9 0.51 10.1 5.9 1.6 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal Spc7 PF08317.11 CRK15077.1 - 0.25 10.2 13.7 0.49 9.2 13.2 1.7 1 1 1 2 2 2 0 Spc7 kinetochore protein ZapB PF06005.12 CRK15077.1 - 0.29 11.6 17.9 0.047 14.1 4.5 3.7 2 1 1 3 3 3 0 Cell division protein ZapB GAS PF13851.6 CRK15077.1 - 0.3 10.4 15.7 0.064 12.6 11.2 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding TolA_bind_tri PF16331.5 CRK15077.1 - 0.42 10.7 6.2 1.3 9.1 0.9 3.0 2 1 0 2 2 2 0 TolA binding protein trimerisation YkyA PF10368.9 CRK15077.1 - 0.49 10.0 7.7 1.1 8.9 7.7 1.6 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein BLOC1_2 PF10046.9 CRK15077.1 - 0.49 10.7 5.2 1.4 9.2 1.9 3.0 4 0 0 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DivIC PF04977.15 CRK15077.1 - 0.53 10.1 15.0 2.3 8.0 5.3 3.5 2 1 1 3 3 3 0 Septum formation initiator YabA PF06156.13 CRK15077.1 - 0.81 10.4 7.7 2.9 8.6 0.1 3.5 2 1 2 4 4 3 0 Initiation control protein YabA Tropomyosin_1 PF12718.7 CRK15077.1 - 0.83 9.8 16.8 0.19 11.9 12.5 2.2 2 0 0 2 2 1 0 Tropomyosin like ADIP PF11559.8 CRK15077.1 - 0.88 9.6 16.0 12 6.0 11.7 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding YscO-like PF16789.5 CRK15077.1 - 0.99 9.4 13.2 68 3.4 13.0 2.7 1 1 1 2 2 2 0 YscO-like protein TMPIT PF07851.13 CRK15077.1 - 1.4 8.1 3.8 3.1 7.0 3.8 1.6 1 0 0 1 1 1 0 TMPIT-like protein DUF4618 PF15397.6 CRK15077.1 - 1.4 8.3 10.3 4.6 6.6 7.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) SOGA PF11365.8 CRK15077.1 - 1.6 9.9 9.8 0.9 10.7 0.5 3.0 2 1 0 3 3 2 0 Protein SOGA DUF2730 PF10805.8 CRK15077.1 - 1.8 8.7 4.4 7.8 6.6 2.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) DUF812 PF05667.11 CRK15077.1 - 3 6.6 14.9 3 6.6 12.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF812) DUF4795 PF16043.5 CRK15077.1 - 3.5 7.2 10.5 12 5.4 1.7 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4795) TMF_TATA_bd PF12325.8 CRK15077.1 - 4.1 7.7 13.3 1.2 9.4 9.0 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding UPF0242 PF06785.11 CRK15077.1 - 4.8 7.3 11.9 0.52 10.4 3.1 2.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Cnn_1N PF07989.11 CRK15077.1 - 5.9 7.1 12.0 1.4 9.2 3.0 3.2 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 KxDL PF10241.9 CRK15077.1 - 8.3 6.8 9.9 12 6.2 1.4 3.2 3 1 1 4 4 2 0 Uncharacterized conserved protein KCH PF16944.5 CRK15084.1 - 3.2e-42 145.1 0.2 3.9e-42 144.8 0.2 1.1 1 0 0 1 1 1 1 Fungal potassium channel Mpp10 PF04006.12 CRK15086.1 - 0.059 11.8 2.7 0.087 11.3 2.7 1.2 1 0 0 1 1 1 0 Mpp10 protein VIR_N PF15912.5 CRK15086.1 - 0.18 11.3 3.4 0.24 11.0 3.4 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal Aminotran_3 PF00202.21 CRK15112.1 - 2.8e-81 273.3 0.3 4.3e-81 272.7 0.3 1.2 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 CRK15112.1 - 0.00059 19.1 0.1 0.001 18.3 0.1 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Metallophos PF00149.28 CRK15120.1 - 2.1e-37 129.6 0.0 3.3e-37 129.0 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase T2SSE PF00437.20 CRK15120.1 - 0.00043 19.4 0.3 0.0018 17.4 0.0 1.9 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_23 PF13476.6 CRK15120.1 - 0.0081 16.7 0.9 2.3 8.7 0.0 2.2 2 0 0 2 2 2 2 AAA domain ATPase PF06745.13 CRK15120.1 - 0.017 14.5 0.9 0.047 13.0 0.0 1.9 2 0 0 2 2 2 0 KaiC PhoH PF02562.16 CRK15120.1 - 0.026 14.0 0.0 0.044 13.2 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_22 PF13401.6 CRK15120.1 - 0.026 14.8 0.3 0.069 13.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 CRK15120.1 - 0.091 12.8 0.1 0.31 11.0 0.0 1.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE FtsK_SpoIIIE PF01580.18 CRK15120.1 - 0.16 11.3 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family SF3b1 PF08920.10 CRK15121.1 - 3.1e-27 95.4 5.8 3.1e-27 95.4 5.8 2.4 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 Cdh1_DBD_1 PF18196.1 CRK15121.1 - 0.031 14.6 0.2 0.059 13.7 0.2 1.4 1 0 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 hGDE_central PF14702.6 CRK15124.1 - 1.6e-29 103.4 1.5 2e-29 103.0 1.5 1.1 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme GDE_C PF06202.14 CRK15124.1 - 6.6e-10 38.5 0.0 8.1e-10 38.2 0.0 1.1 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase ABC_tran PF00005.27 CRK15126.1 - 9.2e-54 181.7 0.0 4.1e-31 108.3 0.0 3.5 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 CRK15126.1 - 1.2e-41 143.2 27.5 1.9e-23 83.5 7.4 4.2 2 2 2 4 4 4 4 ABC transporter transmembrane region SMC_N PF02463.19 CRK15126.1 - 7.4e-16 58.3 0.0 5.4e-06 26.0 0.0 3.2 2 1 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CRK15126.1 - 0.00017 21.5 0.6 1.8 8.3 0.1 3.3 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_ATPase PF09818.9 CRK15126.1 - 0.00041 19.3 2.3 0.0021 16.9 0.0 2.5 3 0 0 3 3 3 1 Predicted ATPase of the ABC class SbcCD_C PF13558.6 CRK15126.1 - 0.00067 19.8 1.4 3.2 8.0 0.0 3.5 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit APS_kinase PF01583.20 CRK15126.1 - 0.0007 19.5 0.0 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_29 PF13555.6 CRK15126.1 - 0.011 15.5 1.2 0.057 13.2 0.1 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.6 CRK15126.1 - 0.034 14.4 1.3 1.3 9.2 0.3 3.2 2 1 0 2 2 2 0 AAA domain Tex_YqgF PF16921.5 CRK15126.1 - 0.035 14.5 0.2 0.11 12.9 0.2 1.9 1 0 0 1 1 1 0 Tex protein YqgF-like domain AAA_23 PF13476.6 CRK15126.1 - 0.14 12.6 1.2 0.29 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CRK15126.1 - 0.25 11.7 5.0 1.2 9.5 1.7 3.1 2 1 0 2 2 2 0 AAA ATPase domain Pec_lyase_C PF00544.19 CRK15127.1 - 1.4e-46 158.8 6.8 5.5e-38 130.7 3.6 2.2 1 1 1 2 2 2 2 Pectate lyase CBM_1 PF00734.18 CRK15127.1 - 7.1e-12 45.1 14.2 1.7e-11 43.8 14.2 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain CAP_GLY PF01302.25 CRK15127.1 - 0.063 13.3 0.1 18 5.4 0.0 2.5 2 0 0 2 2 2 0 CAP-Gly domain DUF1902 PF08972.11 CRK15127.1 - 0.12 12.4 1.2 18 5.4 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1902) Glyco_hydro_61 PF03443.14 CRK15128.1 - 1.1e-56 192.0 0.0 1.4e-56 191.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF5624 PF18538.1 CRK15128.1 - 0.0081 16.3 0.0 0.014 15.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5624) Lustrin_cystein PF14625.6 CRK15129.1 - 1.6 9.1 10.9 14 6.2 0.5 3.7 3 0 0 3 3 3 0 Lustrin, cysteine-rich repeated domain Melibiase_2 PF16499.5 CRK15130.1 - 5.4e-47 160.3 1.6 4.4e-26 91.7 0.2 2.4 1 1 1 2 2 2 2 Alpha galactosidase A Melibiase_C PF17801.1 CRK15130.1 - 1.9e-12 47.0 0.7 1.9e-12 47.0 0.7 1.9 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 CRK15130.1 - 0.04 12.9 0.4 0.4 9.6 0.0 2.5 3 0 0 3 3 3 0 Melibiase Phospholip_A2_3 PF09056.11 CRK15131.1 - 7.6e-40 136.0 3.1 1e-39 135.6 3.1 1.2 1 0 0 1 1 1 1 Prokaryotic phospholipase A2 PLA2G12 PF06951.11 CRK15131.1 - 0.011 15.6 0.1 0.015 15.2 0.1 1.3 1 0 0 1 1 1 0 Group XII secretory phospholipase A2 precursor (PLA2G12) Arm-DNA-bind_2 PF12167.8 CRK15131.1 - 0.14 12.1 0.9 4.2 7.4 0.2 2.3 2 0 0 2 2 2 0 Arm DNA-binding domain ECH_1 PF00378.20 CRK15133.1 - 2e-65 220.6 0.1 1.2e-51 175.4 0.2 2.0 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CRK15133.1 - 1.2e-24 87.5 0.6 1.1e-16 61.3 0.6 3.0 1 1 2 3 3 3 3 Enoyl-CoA hydratase/isomerase SDH_sah PF01972.16 CRK15133.1 - 0.13 11.3 0.1 0.27 10.2 0.1 1.4 1 1 0 1 1 1 0 Serine dehydrogenase proteinase AMP-binding PF00501.28 CRK15134.1 - 2.4e-83 280.1 0.0 3.5e-83 279.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CRK15134.1 - 0.1 13.6 0.0 0.28 12.2 0.0 1.8 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain PhoLip_ATPase_C PF16212.5 CRK15134.1 - 0.21 11.3 5.6 0.41 10.4 5.6 1.4 1 0 0 1 1 1 0 Phospholipid-translocating P-type ATPase C-terminal FtsX PF02687.21 CRK15134.1 - 0.79 10.2 7.0 0.17 12.4 3.1 1.9 2 0 0 2 2 2 0 FtsX-like permease family Fungal_trans PF04082.18 CRK15135.1 - 2.1e-09 36.8 0.4 7.9e-09 34.9 0.3 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK15135.1 - 0.0054 16.8 0.3 0.011 15.8 0.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PhoU PF01895.19 CRK15135.1 - 0.034 14.6 0.9 2.8 8.4 0.1 2.6 3 0 0 3 3 3 0 PhoU domain ABC2_membrane PF01061.24 CRK15136.1 - 5.8e-80 267.6 54.3 2.5e-45 154.5 27.4 2.4 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 CRK15136.1 - 2e-38 132.0 0.0 5.5e-19 69.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 CRK15136.1 - 1.8e-24 85.4 0.0 1.8e-24 85.4 0.0 3.7 4 0 0 4 4 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 CRK15136.1 - 4.3e-14 52.4 31.7 7.7e-10 38.4 14.2 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_trans_N PF14510.6 CRK15136.1 - 8.3e-08 32.7 0.0 2e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 CRK15136.1 - 1.4e-06 28.8 0.2 0.00099 19.5 0.1 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 CRK15136.1 - 2.3e-05 24.1 0.1 0.0046 16.5 0.1 2.4 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 CRK15136.1 - 0.00015 21.7 0.1 0.0021 18.0 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 CRK15136.1 - 0.00046 19.9 0.4 0.084 12.6 0.1 2.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.6 CRK15136.1 - 0.00047 20.3 0.3 1.4 9.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 CRK15136.1 - 0.0021 18.3 1.1 1.1 9.5 0.5 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 CRK15136.1 - 0.0022 18.2 0.2 1.2 9.4 0.0 3.7 4 1 0 4 4 3 1 AAA domain AAA_30 PF13604.6 CRK15136.1 - 0.0028 17.4 0.3 1.9 8.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain cobW PF02492.19 CRK15136.1 - 0.0035 16.9 0.6 1.7 8.2 0.3 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 CRK15136.1 - 0.013 16.1 0.0 4.4 7.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 CRK15136.1 - 0.041 12.9 0.1 1.9 7.4 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein NACHT PF05729.12 CRK15136.1 - 0.088 12.7 0.6 4.3 7.2 0.2 2.4 2 0 0 2 2 2 0 NACHT domain AAA_21 PF13304.6 CRK15136.1 - 0.14 11.9 0.1 6.3 6.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Glyco_transf_90 PF05686.12 CRK15137.1 - 1.3e-13 50.6 0.0 1.3e-13 50.6 0.0 1.4 2 0 0 2 2 2 1 Glycosyl transferase family 90 Zn_clus PF00172.18 CRK15137.1 - 2.5e-05 24.3 10.9 5.2e-05 23.3 10.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 CRK15137.1 - 0.00016 20.8 0.0 0.0004 19.5 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Gly-rich_Ago1 PF12764.7 CRK15138.1 - 0.07 13.9 0.2 0.082 13.7 0.2 1.1 1 0 0 1 1 1 0 Glycine-rich region of argonaut PGPGW PF09656.10 CRK15139.1 - 0.071 12.6 0.3 0.071 12.6 0.3 3.0 3 0 0 3 3 3 0 Putative transmembrane protein (PGPGW) Glyoxalase PF00903.25 CRK15140.1 - 5.5e-07 29.8 0.0 3.4e-06 27.3 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 CRK15140.1 - 1.1e-05 25.7 0.0 1.4e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 CRK15140.1 - 0.0054 16.9 0.0 0.023 14.8 0.0 1.8 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 CRK15140.1 - 0.18 11.8 0.0 0.26 11.2 0.0 1.6 1 1 0 1 1 1 0 Glyoxalase-like domain OPT PF03169.15 CRK15141.1 - 4.3e-103 346.1 34.0 7.8e-98 328.7 24.2 2.0 1 1 1 2 2 2 2 OPT oligopeptide transporter protein DUF4131 PF13567.6 CRK15141.1 - 1.4 8.5 12.6 1 9.0 0.4 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) WSC PF01822.19 CRK15143.1 - 7.3e-56 186.3 46.5 8.8e-18 64.3 7.3 4.6 4 0 0 4 4 4 4 WSC domain ASH PF15780.5 CRK15143.1 - 1.3e-05 25.3 7.2 0.026 14.7 0.0 3.3 3 0 0 3 3 3 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin RBDV_coat PF06593.11 CRK15144.1 - 0.08 12.4 0.2 0.087 12.3 0.2 1.1 1 0 0 1 1 1 0 Raspberry bushy dwarf virus coat protein Evr1_Alr PF04777.13 CRK15145.1 - 5e-26 91.1 0.0 8.1e-26 90.4 0.0 1.3 1 0 0 1 1 1 1 Erv1 / Alr family LmjF365940-deam PF14421.6 CRK15145.1 - 0.003 17.2 0.0 0.0041 16.7 0.0 1.1 1 0 0 1 1 1 1 A distinct subfamily of CDD/CDA-like deaminases SNAD4 PF18750.1 CRK15145.1 - 0.026 14.6 0.0 0.044 13.9 0.0 1.3 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC1 PF18769.1 CRK15145.1 - 0.047 13.9 0.2 1.2 9.5 0.1 2.2 2 0 0 2 2 2 0 APOBEC1 APOBEC4 PF18775.1 CRK15145.1 - 0.12 12.6 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 APOBEC4 Cyclin PF08613.11 CRK15146.1 - 4.6e-43 147.4 0.9 8.9e-25 87.9 0.1 2.7 2 0 0 2 2 2 2 Cyclin Cwf_Cwc_15 PF04889.12 CRK15146.1 - 0.0019 18.0 3.2 0.0034 17.1 3.2 1.3 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Astro_capsid_p PF12226.8 CRK15146.1 - 0.97 8.5 9.4 1.6 7.8 9.4 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein FYDLN_acid PF09538.10 CRK15146.1 - 2 9.1 12.3 0.14 12.9 6.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Glyoxalase PF00903.25 CRK15147.1 - 0.0091 16.2 0.0 0.13 12.5 0.0 2.0 1 1 1 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Cation_ATPase_C PF00689.21 CRK15148.1 - 1.1e-37 129.5 5.3 1.4e-37 129.1 5.3 1.2 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 CRK15148.1 - 1.2e-20 74.7 0.0 3e-19 70.1 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CRK15148.1 - 4.3e-07 29.9 0.0 6.2e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CRK15148.1 - 0.039 14.4 0.0 0.071 13.5 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CRK15148.1 - 0.087 12.9 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Cation transport ATPase (P-type) Ldr_toxin PF13940.6 CRK15148.1 - 0.22 11.6 1.2 0.93 9.6 1.2 2.1 1 0 0 1 1 1 0 Toxin Ldr, type I toxin-antitoxin system Cation_ATPase_C PF00689.21 CRK15149.1 - 3.5e-18 65.9 1.8 3.5e-18 65.9 1.8 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 CRK15149.1 - 3.1e-15 56.2 0.2 4.8e-11 42.5 0.0 3.2 2 1 1 3 3 3 2 E1-E2 ATPase Cation_ATPase PF13246.6 CRK15149.1 - 3.2e-14 52.8 0.0 6.6e-14 51.8 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 CRK15149.1 - 9.6e-14 50.8 0.0 4.1e-12 45.6 0.0 2.7 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 CRK15149.1 - 5.4e-08 33.4 0.0 1e-07 32.5 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2157 PF09925.9 CRK15149.1 - 0.00044 20.1 0.4 0.0022 17.8 0.1 2.3 2 1 0 2 2 2 1 Predicted membrane protein (DUF2157) DUF3619 PF12279.8 CRK15149.1 - 0.046 14.1 0.5 2.5 8.4 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3619) TFIIA PF03153.13 CRK15152.1 - 0.47 10.4 4.4 0.6 10.1 4.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit S-methyl_trans PF02574.16 CRK15153.1 - 1.1e-113 379.5 0.0 4.9e-55 187.2 0.0 3.0 3 0 0 3 3 3 3 Homocysteine S-methyltransferase DUF2617 PF10936.8 CRK15153.1 - 0.00031 20.9 0.0 13 5.9 0.0 3.4 3 0 0 3 3 3 3 Protein of unknown function DUF2617 Kelch_1 PF01344.25 CRK15153.1 - 0.0082 15.7 2.6 4.5 6.9 0.0 3.4 4 0 0 4 4 4 2 Kelch motif AP2 PF00847.20 CRK15153.1 - 0.14 12.4 0.0 37 4.6 0.0 2.7 2 0 0 2 2 2 0 AP2 domain Prok-RING_2 PF14445.6 CRK15153.1 - 0.59 10.3 3.1 25 5.2 0.2 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 HTH_32 PF13565.6 CRK15154.1 - 0.14 12.8 0.1 0.14 12.8 0.1 2.0 3 0 0 3 3 3 0 Homeodomain-like domain CBM_1 PF00734.18 CRK15155.1 - 1.3e-07 31.4 11.5 2.3e-07 30.6 11.5 1.4 1 0 0 1 1 1 1 Fungal cellulose binding domain DUF2205 PF10224.9 CRK15156.1 - 7.1e-35 118.8 0.2 1.1e-34 118.2 0.2 1.3 1 0 0 1 1 1 1 Short coiled-coil protein AAA_32 PF13654.6 CRK15156.1 - 0.032 13.0 0.1 0.037 12.8 0.1 1.1 1 0 0 1 1 1 0 AAA domain IMUP PF15761.5 CRK15156.1 - 0.038 14.7 2.5 0.073 13.8 2.5 1.5 1 0 0 1 1 1 0 Immortalisation up-regulated protein DUF4573 PF15140.6 CRK15156.1 - 0.06 13.1 5.2 0.41 10.4 4.3 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4573) Bac_rhodopsin PF01036.18 CRK15157.1 - 5.7e-05 22.8 1.6 7.7e-05 22.4 1.6 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF1516 PF07457.11 CRK15157.1 - 0.046 13.9 0.1 0.054 13.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1516) RPE65 PF03055.15 CRK15158.1 - 5.4e-141 470.9 0.0 4.9e-88 296.3 0.0 2.0 1 1 1 2 2 2 2 Retinal pigment epithelial membrane protein E1-E2_ATPase PF00122.20 CRK15159.1 - 1.5e-33 115.8 22.4 1.2e-28 99.9 0.1 3.9 4 0 0 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 CRK15159.1 - 9.4e-28 97.1 0.4 9.4e-28 97.1 0.4 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 CRK15159.1 - 1.7e-17 64.4 0.1 4.8e-16 59.7 0.1 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CRK15159.1 - 9.7e-15 54.0 0.0 2.4e-14 52.8 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 CRK15159.1 - 2.4e-14 53.2 0.0 4.7e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CRK15159.1 - 3.3e-07 30.3 1.8 1.9e-05 24.5 0.5 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase CorA PF01544.18 CRK15162.1 - 0.035 13.4 0.1 0.068 12.5 0.1 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein 7tm_7 PF08395.12 CRK15162.1 - 0.044 13.0 0.0 0.069 12.4 0.0 1.2 1 0 0 1 1 1 0 7tm Chemosensory receptor Fimbrial PF00419.20 CRK15162.1 - 0.15 12.3 0.0 0.26 11.6 0.0 1.3 1 0 0 1 1 1 0 Fimbrial protein LapA_dom PF06305.11 CRK15162.1 - 0.2 11.5 1.4 3 7.7 0.1 2.5 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain HsbA PF12296.8 CRK15163.1 - 2.2e-26 92.6 20.3 2.2e-26 92.6 20.3 2.1 2 0 0 2 2 2 1 Hydrophobic surface binding protein A T3SS_TC PF06511.11 CRK15163.1 - 0.15 11.4 4.0 0.2 11.0 4.0 1.1 1 0 0 1 1 1 0 Type III secretion systems tip complex components Pribosyltran_N PF13793.6 CRK15164.1 - 6.1e-43 145.5 0.1 1.2e-42 144.5 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 CRK15164.1 - 3.6e-33 115.1 0.9 7.2e-33 114.2 0.2 1.8 2 0 0 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 CRK15164.1 - 4.3e-07 29.6 0.3 1.2e-06 28.1 0.1 1.9 2 0 0 2 2 2 1 Phosphoribosyl transferase domain SNF2_N PF00176.23 CRK15165.1 - 3e-65 220.3 0.2 5.3e-65 219.4 0.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CRK15165.1 - 7e-19 68.2 0.0 1e-17 64.5 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CRK15165.1 - 5.2e-10 39.6 0.0 1.1e-09 38.5 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HSA PF07529.13 CRK15165.1 - 3.3e-05 24.1 7.7 3.3e-05 24.1 7.7 2.6 1 1 1 2 2 2 1 HSA DEAD PF00270.29 CRK15165.1 - 0.00039 20.2 0.0 0.00083 19.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 CRK15165.1 - 0.13 11.5 0.1 2.6 7.1 0.0 2.6 2 1 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 DEAD_2 PF06733.15 CRK15165.1 - 0.18 11.4 0.0 0.39 10.3 0.0 1.4 1 0 0 1 1 1 0 DEAD_2 NDUF_B8 PF05821.11 CRK15166.1 - 3.4e-09 36.8 2.1 5.7e-09 36.1 2.1 1.4 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) ADH_N PF08240.12 CRK15167.1 - 4.9e-05 23.2 0.1 0.0006 19.7 0.1 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain DUF4129 PF13559.6 CRK15167.1 - 0.25 11.6 1.9 16 5.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4129) Coiled PF05710.12 CRK15168.1 - 0.086 13.7 1.6 0.16 12.8 1.6 1.4 1 0 0 1 1 1 0 Coiled coil Presenilin PF01080.17 CRK15168.1 - 0.4 9.4 0.7 0.35 9.6 0.7 1.2 1 0 0 1 1 1 0 Presenilin Spt20 PF12090.8 CRK15168.1 - 0.67 9.5 15.2 1.1 8.8 15.2 1.3 1 0 0 1 1 1 0 Spt20 family Roughex PF06020.11 CRK15168.1 - 0.67 9.0 7.2 0.91 8.6 7.2 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Herpes_pp85 PF04637.12 CRK15168.1 - 1 7.7 3.8 1.4 7.3 3.8 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Aa_trans PF01490.18 CRK15182.1 - 1.6e-63 214.9 16.8 1.8e-63 214.6 16.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Spt5_N PF11942.8 CRK15182.1 - 4 8.5 8.7 3.6 8.6 2.4 2.2 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Fungal_trans PF04082.18 CRK15197.1 - 8.7e-28 97.1 0.3 8.7e-28 97.1 0.3 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Beta_helix PF13229.6 CRK15197.1 - 5.3e-07 29.6 0.1 7.5e-07 29.1 0.1 1.2 1 0 0 1 1 1 1 Right handed beta helix region NosD PF05048.13 CRK15197.1 - 9.1e-06 25.1 0.3 1.3e-05 24.6 0.3 1.2 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) HsbA PF12296.8 CRK15214.1 - 2.7e-12 47.2 5.3 3.1e-12 47.0 5.3 1.1 1 0 0 1 1 1 1 Hydrophobic surface binding protein A V-SNARE_C PF12352.8 CRK15216.1 - 0.031 14.5 1.5 0.091 13.1 1.5 1.7 1 0 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus CorA PF01544.18 CRK15216.1 - 5.3 6.3 7.1 1.2 8.4 3.6 1.6 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein NPR3 PF03666.13 CRK15217.1 - 2.7e-08 33.1 0.4 2.7e-08 33.1 0.4 1.4 2 0 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 GxGYxYP_N PF16216.5 CRK15217.1 - 0.065 13.4 0.1 0.09 12.9 0.1 1.2 1 0 0 1 1 1 0 GxGYxY sequence motif in domain of unknown function N-terminal Sec6 PF06046.13 CRK15218.1 - 8e-43 146.7 0.1 1.3e-42 146.0 0.0 1.4 1 1 0 1 1 1 1 Exocyst complex component Sec6 Vps53_N PF04100.12 CRK15218.1 - 2.8e-05 23.3 1.4 4.8e-05 22.5 0.2 1.8 2 0 0 2 2 2 1 Vps53-like, N-terminal DUF755 PF05501.11 CRK15218.1 - 0.011 16.0 0.1 0.024 14.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF755) OmdA PF13376.6 CRK15218.1 - 0.032 14.2 0.0 0.075 13.1 0.0 1.6 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated Syntaxin_2 PF14523.6 CRK15218.1 - 0.066 13.6 2.9 2.8 8.3 0.4 2.4 2 0 0 2 2 2 0 Syntaxin-like protein DASH_Duo1 PF08651.10 CRK15218.1 - 0.1 12.4 0.7 0.35 10.7 0.2 2.2 2 0 0 2 2 2 0 DASH complex subunit Duo1 Fmp27_WPPW PF10359.9 CRK15219.1 - 0.36 9.6 2.9 0.55 9.0 2.9 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF2009 PF09418.10 CRK15219.1 - 1.2 8.1 2.4 1.6 7.7 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) Abhydrolase_1 PF00561.20 CRK15220.1 - 3e-22 79.5 0.1 7.6e-17 61.8 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CRK15220.1 - 1.5e-15 58.4 0.1 1.9e-15 58.1 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CRK15220.1 - 5.1e-08 32.5 0.0 1.5e-07 30.9 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 CRK15220.1 - 1.2e-05 25.2 0.0 0.00024 20.9 0.0 2.1 1 1 0 1 1 1 1 PGAP1-like protein Esterase PF00756.20 CRK15220.1 - 0.00017 21.3 0.0 0.00079 19.2 0.0 1.9 1 1 0 1 1 1 1 Putative esterase Thioesterase PF00975.20 CRK15220.1 - 0.00026 21.2 0.0 0.00055 20.1 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Chlorophyllase PF07224.11 CRK15220.1 - 0.011 14.8 0.0 0.023 13.7 0.0 1.5 1 0 0 1 1 1 0 Chlorophyllase Chlorophyllase2 PF12740.7 CRK15220.1 - 0.044 12.7 0.0 0.12 11.3 0.0 1.6 2 0 0 2 2 2 0 Chlorophyllase enzyme DUF676 PF05057.14 CRK15220.1 - 0.075 12.5 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Palm_thioest PF02089.15 CRK15220.1 - 0.088 12.6 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Not1 PF04054.15 CRK15221.1 - 8.4e-109 363.8 0.0 1.9e-108 362.7 0.0 1.6 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 CRK15221.1 - 1.9e-89 298.9 0.9 4.3e-89 297.8 0.9 1.6 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 CRK15221.1 - 3.1e-50 169.9 0.7 1.1e-49 168.1 0.7 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 CRK15221.1 - 4.9e-42 143.3 0.0 2e-41 141.3 0.0 2.0 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 CRK15221.1 - 2.9e-36 124.8 0.4 2.9e-36 124.8 0.4 2.1 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 HEAT repeat Ribosomal_S3Ae PF01015.18 CRK15221.1 - 2.5e-30 105.6 0.3 5.9e-30 104.4 0.3 1.6 1 0 0 1 1 1 1 Ribosomal S3Ae family EPO_TPO PF00758.18 CRK15221.1 - 0.11 12.5 0.1 0.29 11.1 0.1 1.6 1 0 0 1 1 1 0 Erythropoietin/thrombopoietin Methyltransf_23 PF13489.6 CRK15222.1 - 1e-15 58.0 0.0 1.5e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK15222.1 - 0.0011 19.6 0.0 0.89 10.3 0.0 3.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CRK15222.1 - 0.0061 15.9 0.0 0.31 10.3 0.0 2.7 3 0 0 3 3 3 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 CRK15222.1 - 0.012 16.3 0.0 0.089 13.5 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 CRK15222.1 - 0.017 15.8 0.0 0.26 12.0 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 CRK15222.1 - 0.019 14.8 0.0 0.26 11.0 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Seipin PF06775.14 CRK15223.1 - 4.5e-56 190.1 0.8 7e-56 189.5 0.8 1.3 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) FCH PF00611.23 CRK15223.1 - 1.3e-13 51.1 0.6 2.6e-13 50.1 0.0 1.9 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 CRK15223.1 - 9.4e-11 41.2 0.0 1.8e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CRK15223.1 - 3e-07 30.0 0.0 1.7e-06 27.6 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 CRK15223.1 - 3.3e-05 23.7 0.1 6.9e-05 22.6 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain Tup_N PF08581.10 CRK15223.1 - 0.32 11.3 1.8 4.7 7.6 0.1 2.7 2 0 0 2 2 2 0 Tup N-terminal NTF2 PF02136.20 CRK15225.1 - 1.5e-32 112.7 0.1 1.7e-32 112.5 0.1 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Circo_capsid PF02443.15 CRK15225.1 - 0.16 11.5 0.0 0.2 11.2 0.0 1.1 1 0 0 1 1 1 0 Circovirus capsid protein MWFE PF15879.5 CRK15226.1 - 5.9e-30 103.2 0.1 1.3e-29 102.1 0.1 1.6 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit Ribosomal_L7Ae PF01248.26 CRK15226.1 - 2.4e-21 75.3 0.5 4e-21 74.5 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family ATP_bind_3 PF01171.20 CRK15227.1 - 2.9e-17 63.0 0.0 6.2e-17 61.9 0.0 1.5 1 0 0 1 1 1 1 PP-loop family zn-ribbon_14 PF16503.5 CRK15227.1 - 3.7e-15 55.1 3.5 3.7e-15 55.1 3.5 3.8 4 0 0 4 4 4 2 Zinc-ribbon RecR PF02132.15 CRK15227.1 - 0.084 12.5 0.3 0.084 12.5 0.3 3.0 4 0 0 4 4 4 0 RecR protein zf-UBR PF02207.20 CRK15227.1 - 0.34 11.1 6.8 5.5 7.2 0.9 2.6 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) TF_Zn_Ribbon PF08271.12 CRK15227.1 - 0.93 9.1 7.2 1.6 8.3 0.2 3.3 3 0 0 3 3 3 0 TFIIB zinc-binding RNHCP PF12647.7 CRK15227.1 - 3.9 7.5 9.9 8 6.5 1.2 2.8 3 0 0 3 3 3 0 RNHCP domain MOZ_SAS PF01853.18 CRK15228.1 - 1.3e-74 249.7 0.0 2e-74 249.1 0.0 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 CRK15228.1 - 1.2e-20 72.8 3.6 2.5e-20 71.8 3.6 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 CRK15228.1 - 0.16 12.4 0.0 0.33 11.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PHD_4 PF16866.5 CRK15228.1 - 0.24 11.5 2.2 0.78 9.9 2.2 1.8 1 0 0 1 1 1 0 PHD-finger HATPase_c PF02518.26 CRK15229.1 - 3e-21 76.0 0.1 6.7e-21 74.9 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 CRK15229.1 - 3.2e-17 62.7 0.0 2e-16 60.2 0.0 2.3 1 1 0 1 1 1 1 Response regulator receiver domain GAF PF01590.26 CRK15229.1 - 5.6e-12 46.4 0.0 2e-11 44.6 0.0 2.0 1 0 0 1 1 1 1 GAF domain PAS_2 PF08446.11 CRK15229.1 - 5.7e-08 33.4 0.0 1.4e-07 32.2 0.0 1.6 1 0 0 1 1 1 1 PAS fold HATPase_c_3 PF13589.6 CRK15229.1 - 0.018 14.9 0.0 0.036 13.9 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_5 PF14501.6 CRK15229.1 - 0.039 13.9 0.0 0.089 12.7 0.0 1.5 1 0 0 1 1 1 0 GHKL domain PAS_9 PF13426.7 CRK15229.1 - 0.08 13.2 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 PAS domain ApbA PF02558.16 CRK15230.1 - 3.3e-33 114.5 0.0 4.5e-33 114.1 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 CRK15230.1 - 6.8e-25 87.7 0.0 1.2e-24 86.9 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 CRK15231.1 - 1.4e-09 37.8 0.0 1.5e-09 37.7 0.0 1.0 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 CRK15231.1 - 0.0087 16.6 0.0 0.01 16.3 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CRK15231.1 - 0.026 14.8 0.1 0.032 14.5 0.1 1.2 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 CRK15231.1 - 0.027 13.5 0.0 0.03 13.4 0.0 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein Sacchrp_dh_NADP PF03435.18 CRK15231.1 - 0.099 12.9 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Adenylsucc_synt PF00709.21 CRK15234.1 - 1.2e-08 34.3 0.0 1.4e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Adenylosuccinate synthetase DUF3677 PF12432.8 CRK15235.1 - 0.14 12.5 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3677) ThiF PF00899.21 CRK15236.1 - 1e-109 365.6 0.0 4.6e-74 248.8 0.0 2.4 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 CRK15236.1 - 2.2e-89 299.7 0.3 5e-89 298.5 0.1 1.7 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 CRK15236.1 - 1.3e-30 106.0 0.1 3.1e-30 104.7 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin fold domain E1_FCCH PF16190.5 CRK15236.1 - 2.2e-30 104.7 0.1 4.7e-30 103.6 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 CRK15236.1 - 4.3e-24 84.5 1.3 1.1e-23 83.2 1.3 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle FKBP_C PF00254.28 CRK15236.1 - 1.9e-23 82.6 0.1 5.2e-23 81.2 0.1 1.7 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Pyr_redox PF00070.27 CRK15236.1 - 0.053 14.1 0.1 14 6.4 0.0 3.5 4 0 0 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase Mrr_N PF14338.6 CRK15236.1 - 0.11 12.7 0.0 1.7 8.8 0.0 2.5 2 0 0 2 2 2 0 Mrr N-terminal domain GST_N_2 PF13409.6 CRK15237.1 - 2.2e-23 82.3 0.2 1.2e-22 80.0 0.0 2.3 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CRK15237.1 - 4.2e-16 58.7 0.1 7.5e-16 57.9 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CRK15237.1 - 3.4e-05 24.2 0.0 0.002 18.5 0.0 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CRK15237.1 - 4.7e-05 23.5 0.0 0.00012 22.3 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 CRK15237.1 - 0.0011 19.5 0.0 0.0022 18.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CRK15237.1 - 0.0049 17.0 0.0 0.01 16.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Chitin_synth_2 PF03142.15 CRK15238.1 - 2.3e-209 696.4 8.3 5.7e-201 668.7 7.7 2.2 1 1 1 2 2 2 2 Chitin synthase Myosin_head PF00063.21 CRK15238.1 - 2.6e-77 260.6 0.0 5.4e-76 256.3 0.0 2.0 1 1 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.11 CRK15238.1 - 5.7e-17 61.4 0.1 1.5e-16 60.0 0.1 1.8 1 0 0 1 1 1 1 DEK C terminal domain Cyt-b5 PF00173.28 CRK15238.1 - 6.5e-17 61.4 0.2 2.7e-13 49.9 0.0 3.5 3 1 0 3 3 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.6 CRK15238.1 - 9.6e-11 42.0 5.7 9.6e-11 42.0 5.7 2.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 CRK15238.1 - 1.2e-08 35.2 0.2 2.6e-08 34.1 0.2 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 CRK15238.1 - 0.00037 20.4 0.0 0.002 18.0 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 2 RsgA_GTPase PF03193.16 CRK15238.1 - 0.007 16.3 0.1 0.018 14.9 0.1 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 CRK15238.1 - 0.008 15.8 0.1 0.018 14.6 0.1 1.5 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 CRK15238.1 - 0.016 15.3 0.1 0.68 10.0 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase ABC_tran PF00005.27 CRK15238.1 - 0.018 15.5 0.2 0.052 14.1 0.0 1.8 2 0 0 2 2 1 0 ABC transporter AAA_16 PF13191.6 CRK15238.1 - 0.027 14.9 0.4 0.11 12.9 0.1 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 CRK15238.1 - 0.061 13.1 0.1 0.21 11.4 0.1 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 CRK15238.1 - 0.064 13.5 0.6 0.24 11.6 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CRK15238.1 - 0.086 12.3 0.0 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 CRK15238.1 - 0.14 12.6 0.0 0.45 10.9 0.0 1.9 1 0 0 1 1 1 0 RNA helicase Glyco_transf_21 PF13506.6 CRK15238.1 - 0.17 11.3 0.3 0.74 9.3 0.3 1.9 1 1 0 1 1 1 0 Glycosyl transferase family 21 Chitin_synth_2 PF03142.15 CRK15239.1 - 5.2e-228 757.9 0.1 7.1e-228 757.5 0.1 1.1 1 0 0 1 1 1 1 Chitin synthase DEK_C PF08766.11 CRK15239.1 - 1.6e-15 56.7 0.6 1.1e-14 54.0 0.9 2.1 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.28 CRK15239.1 - 2.2e-15 56.5 0.2 1.9e-10 40.8 0.0 3.0 3 0 0 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.6 CRK15239.1 - 2.2e-13 50.6 2.2 2.2e-13 50.6 2.2 1.8 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 CRK15239.1 - 1.1e-09 38.5 0.0 4.3e-09 36.6 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Myosin_head PF00063.21 CRK15239.1 - 8.1e-08 30.9 0.0 2.1e-07 29.6 0.0 1.6 1 1 0 1 1 1 1 Myosin head (motor domain) Glycos_transf_2 PF00535.26 CRK15239.1 - 0.00054 19.8 0.0 0.082 12.7 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 CRK15239.1 - 0.0021 17.6 0.0 0.0074 15.8 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 21 FA_desaturase PF00487.24 CRK15239.1 - 3.2 7.5 9.8 5.2 6.8 1.3 2.4 2 0 0 2 2 2 0 Fatty acid desaturase PAS_3 PF08447.12 CRK15240.1 - 2.8e-14 53.2 0.0 3.3e-10 40.1 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 CRK15240.1 - 1.5e-06 28.4 0.0 0.0029 17.8 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 CRK15240.1 - 0.0011 19.0 0.0 0.85 9.6 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 CRK15240.1 - 0.0045 17.2 0.7 0.85 9.9 0.0 3.1 3 0 0 3 3 3 1 PAS fold PAS_11 PF14598.6 CRK15240.1 - 0.015 15.4 0.0 0.054 13.6 0.0 1.8 2 0 0 2 2 2 0 PAS domain Ribosomal_S28e PF01200.18 CRK15241.1 - 3e-31 107.2 2.3 3.4e-31 107.0 2.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e WD40 PF00400.32 CRK15242.1 - 5.3e-13 49.2 9.8 1.2e-05 25.9 0.1 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK15242.1 - 0.057 13.7 0.0 1.3 9.4 0.0 2.5 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain NPR3 PF03666.13 CRK15244.1 - 2.5e-66 224.4 3.4 3e-66 224.1 3.4 1.1 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 CSG2 PF16965.5 CRK15244.1 - 0.066 12.2 0.1 0.093 11.7 0.1 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator Choline_kinase PF01633.20 CRK15245.1 - 5.7e-22 78.4 0.0 7.5e-22 78.0 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase E1-E2_ATPase PF00122.20 CRK15247.1 - 7.6e-09 35.3 0.0 1.9e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 CRK15247.1 - 0.07 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus Ldh_1_C PF02866.18 CRK15248.1 - 3e-45 154.1 0.0 5.1e-45 153.4 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 CRK15248.1 - 3.2e-43 147.2 0.0 7.4e-43 146.0 0.1 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 CRK15248.1 - 0.00014 21.0 0.0 0.00021 20.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 CRK15248.1 - 0.069 13.6 0.1 0.21 12.0 0.0 1.9 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Velvet PF11754.8 CRK15280.1 - 1.2e-93 313.7 8.9 8.1e-93 311.0 0.0 2.2 2 0 0 2 2 2 1 Velvet factor Methyltransf_28 PF02636.17 CRK15282.1 - 2.9e-33 115.6 0.0 4.1e-33 115.1 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.16 CRK15282.1 - 7.5e-05 22.7 0.0 0.00012 22.0 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase ADH_N PF08240.12 CRK15283.1 - 3.1e-29 101.0 0.5 7.5e-29 99.8 0.5 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CRK15283.1 - 9.3e-23 80.6 0.2 1.9e-22 79.6 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 CRK15283.1 - 3e-10 40.0 0.6 5.3e-10 39.1 0.6 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 CRK15283.1 - 6.5e-06 27.2 0.1 3.1e-05 25.0 0.0 2.1 1 1 1 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 CRK15283.1 - 0.00065 19.1 1.3 0.0012 18.2 1.3 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 CRK15283.1 - 0.0039 16.8 0.0 0.0075 15.9 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_2 PF07992.14 CRK15283.1 - 0.024 13.9 0.0 0.055 12.7 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PALP PF00291.25 CRK15283.1 - 0.034 13.6 1.1 0.054 12.9 1.1 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme AdoHcyase_NAD PF00670.21 CRK15283.1 - 0.078 13.0 1.1 0.81 9.7 0.7 2.3 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Methyltransf_25 PF13649.6 CRK15283.1 - 0.088 13.5 0.4 0.29 11.9 0.1 2.0 2 0 0 2 2 2 0 Methyltransferase domain VHL_C PF17211.3 CRK15284.1 - 0.23 11.5 2.4 0.79 9.8 0.1 2.7 3 0 0 3 3 3 0 VHL box domain Pectate_lyase PF03211.13 CRK15285.1 - 6.9e-70 234.7 2.3 9.5e-70 234.3 2.3 1.2 1 0 0 1 1 1 1 Pectate lyase F-box-like PF12937.7 CRK15287.1 - 0.00023 21.0 0.2 0.00053 19.8 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CRK15287.1 - 0.00032 20.5 0.0 0.00061 19.6 0.0 1.4 1 0 0 1 1 1 1 F-box domain F-box-like_2 PF13013.6 CRK15287.1 - 0.026 14.5 0.0 0.029 14.3 0.0 1.4 1 1 0 1 1 1 0 F-box-like domain DUF4835 PF16119.5 CRK15287.1 - 0.11 11.6 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4835) Glyco_tran_28_C PF04101.16 CRK15289.1 - 5.7e-19 68.7 0.0 1e-18 67.9 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain SLIDE PF09111.10 CRK15290.1 - 1.9e-41 140.6 1.0 5.4e-41 139.2 1.0 1.8 1 0 0 1 1 1 1 SLIDE SNF2_N PF00176.23 CRK15290.1 - 1.9e-35 122.2 0.0 4.1e-35 121.1 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain HAND PF09110.11 CRK15290.1 - 4.3e-35 120.8 3.2 4.3e-35 120.8 3.2 3.6 4 0 0 4 4 4 1 HAND WD40 PF00400.32 CRK15290.1 - 7.1e-21 74.1 22.9 0.0023 18.7 0.2 9.6 9 0 0 9 9 9 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK15290.1 - 2.2e-13 50.3 1.5 0.00045 20.5 0.0 5.9 4 2 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Helicase_C PF00271.31 CRK15290.1 - 5.5e-12 46.0 0.0 2.9e-11 43.7 0.0 2.2 1 1 1 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CRK15290.1 - 2.1e-09 37.6 1.8 9.4e-09 35.5 0.0 3.0 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CRK15290.1 - 0.00022 21.1 0.1 0.00075 19.3 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF1086 PF06461.11 CRK15290.1 - 0.0054 16.6 0.1 0.016 15.0 0.1 1.8 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1086) PQQ_3 PF13570.6 CRK15290.1 - 0.006 17.0 5.0 3.7 8.2 1.0 4.6 3 1 0 3 3 3 1 PQQ-like domain Ge1_WD40 PF16529.5 CRK15290.1 - 0.0064 15.5 2.3 2.6 6.9 0.0 4.1 4 1 1 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein CPSF_A PF03178.15 CRK15290.1 - 0.022 14.1 0.0 0.045 13.1 0.0 1.5 1 0 0 1 1 1 0 CPSF A subunit region DEAD_2 PF06733.15 CRK15290.1 - 0.081 12.5 0.1 0.17 11.5 0.1 1.4 1 0 0 1 1 1 0 DEAD_2 Occludin_ELL PF07303.13 CRK15290.1 - 0.32 11.7 5.7 0.82 10.4 5.7 1.7 1 0 0 1 1 1 0 Occludin homology domain NYD-SP28_assoc PF14775.6 CRK15290.1 - 0.67 10.1 2.5 4 7.6 2.5 2.4 1 0 0 1 1 1 0 Sperm tail C-terminal domain DUF4588 PF15251.6 CRK15291.1 - 2.7e-07 30.6 0.1 3e-07 30.5 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4588) Glyco_tranf_2_2 PF10111.9 CRK15291.1 - 0.12 11.9 0.0 0.14 11.6 0.0 1.0 1 0 0 1 1 1 0 Glycosyltransferase like family 2 WD40 PF00400.32 CRK15292.1 - 2.5e-23 81.9 0.2 1.3e-07 32.1 0.2 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK15292.1 - 1.2e-12 47.9 0.0 0.0045 17.3 0.1 4.8 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CRK15292.1 - 0.00057 18.6 0.0 0.00083 18.1 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 eIF2A PF08662.11 CRK15292.1 - 0.00084 19.3 0.1 2 8.2 0.0 3.0 2 2 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 CRK15292.1 - 0.0021 17.4 0.0 0.03 13.6 0.0 2.2 1 1 0 2 2 2 1 WD40-like domain Coatomer_WDAD PF04053.14 CRK15292.1 - 0.0029 16.7 0.0 0.11 11.5 0.0 2.1 1 1 1 2 2 2 1 Coatomer WD associated region PQQ_2 PF13360.6 CRK15292.1 - 0.0059 16.2 0.0 0.42 10.2 0.0 2.3 1 1 0 1 1 1 1 PQQ-like domain Ge1_WD40 PF16529.5 CRK15292.1 - 0.069 12.1 1.2 7 5.5 0.0 2.6 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein FTHFS PF01268.19 CRK15293.1 - 2.9e-255 847.7 0.1 4e-255 847.3 0.1 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 CRK15293.1 - 2.7e-69 231.6 2.9 6.3e-69 230.4 1.4 2.2 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 CRK15293.1 - 4.9e-20 71.9 0.2 2e-19 70.0 0.1 2.0 1 1 1 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain AlaDh_PNT_C PF01262.21 CRK15293.1 - 0.044 13.1 0.1 0.11 11.7 0.1 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF1997 PF09366.10 CRK15293.1 - 0.15 12.2 0.0 0.65 10.1 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1997) FAD_binding_4 PF01565.23 CRK15294.1 - 1.7e-21 76.4 3.7 4.5e-21 75.0 3.7 1.8 1 0 0 1 1 1 1 FAD binding domain NAD_binding_6 PF08030.12 CRK15294.1 - 4.4e-21 75.6 0.0 7.5e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 CRK15294.1 - 4.4e-16 59.1 12.3 4.4e-16 59.1 12.3 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 CRK15294.1 - 8e-08 32.3 0.0 1.8e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain BBE PF08031.12 CRK15294.1 - 0.0068 16.5 0.0 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like NAD_binding_1 PF00175.21 CRK15294.1 - 0.014 16.0 0.0 0.78 10.4 0.0 2.5 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain RTA1 PF04479.13 CRK15295.1 - 5.8e-38 130.6 9.3 7.1e-38 130.3 9.3 1.1 1 0 0 1 1 1 1 RTA1 like protein MIG-14_Wnt-bd PF06664.12 CRK15295.1 - 0.002 17.4 5.2 0.0031 16.8 5.2 1.3 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion PGAP1 PF07819.13 CRK15296.1 - 1.2e-06 28.4 0.1 1.8e-06 27.9 0.1 1.2 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 CRK15296.1 - 8.6e-06 25.4 0.1 1.5e-05 24.6 0.1 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Thioesterase PF00975.20 CRK15296.1 - 2.4e-05 24.6 0.1 3e-05 24.2 0.1 1.2 1 0 0 1 1 1 1 Thioesterase domain Palm_thioest PF02089.15 CRK15296.1 - 5e-05 23.3 0.0 7.1e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.7 CRK15296.1 - 0.00041 21.0 9.3 0.00057 20.5 9.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CRK15296.1 - 0.0009 19.0 0.3 0.0053 16.4 0.3 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold LCAT PF02450.15 CRK15296.1 - 0.001 18.3 0.0 0.0014 17.8 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.8 CRK15296.1 - 0.076 12.3 0.2 0.19 11.0 0.1 1.6 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 CRK15296.1 - 0.16 11.8 0.1 0.4 10.5 0.1 1.6 2 0 0 2 2 2 0 Serine hydrolase Lipase_2 PF01674.18 CRK15296.1 - 0.25 10.8 0.0 0.51 9.8 0.1 1.4 2 0 0 2 2 2 0 Lipase (class 2) Arrestin_N PF00339.29 CRK15297.1 - 4e-17 62.6 0.0 7.3e-12 45.6 0.0 3.1 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain zf-MIZ PF02891.20 CRK15298.1 - 1.8e-08 34.0 8.9 1.7e-06 27.7 4.8 3.0 2 1 0 2 2 2 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 CRK15298.1 - 0.07 13.0 0.5 0.23 11.3 0.0 2.0 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit PGAP1 PF07819.13 CRK15299.1 - 1.1e-06 28.6 0.1 1.8e-06 27.9 0.1 1.3 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.20 CRK15299.1 - 6.2e-06 26.5 0.1 9.2e-06 25.9 0.1 1.3 1 0 0 1 1 1 1 Thioesterase domain DUF676 PF05057.14 CRK15299.1 - 2.7e-05 23.8 0.1 4.5e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 CRK15299.1 - 4.7e-05 23.3 0.0 7.3e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.7 CRK15299.1 - 0.00022 21.9 9.2 0.00022 21.9 9.2 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family LCAT PF02450.15 CRK15299.1 - 0.0012 18.1 0.0 0.0018 17.5 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_1 PF00561.20 CRK15299.1 - 0.0026 17.4 0.4 0.016 14.9 0.4 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold FliT PF05400.13 CRK15299.1 - 0.055 14.3 0.0 0.77 10.6 0.0 2.3 2 0 0 2 2 2 0 Flagellar protein FliT Hydrolase_4 PF12146.8 CRK15299.1 - 0.089 12.0 0.2 0.23 10.7 0.1 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 CRK15299.1 - 0.17 11.8 0.5 0.34 10.7 0.0 1.7 2 0 0 2 2 2 0 Serine hydrolase Arrestin_N PF00339.29 CRK15300.1 - 2.6e-17 63.2 0.0 4.5e-12 46.2 0.0 3.1 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain zf-MIZ PF02891.20 CRK15301.1 - 1.7e-07 30.9 10.0 2.2e-06 27.3 5.0 2.7 2 1 0 2 2 2 1 MIZ/SP-RING zinc finger ATG16 PF08614.11 CRK15301.1 - 0.92 9.7 7.4 2.5 8.3 7.4 1.7 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) VanY PF02557.17 CRK15301.1 - 3.5 7.4 8.1 8.3 6.2 1.9 2.5 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase SAM_2 PF07647.17 CRK15302.1 - 1.1e-12 47.9 0.0 2.1e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.6 CRK15302.1 - 1.2e-12 47.4 0.0 2.7e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CRK15302.1 - 6.8e-10 38.4 0.0 1.3e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain PH PF00169.29 CRK15302.1 - 1.4e-09 38.4 0.0 4.7e-09 36.7 0.0 1.9 1 1 0 1 1 1 1 PH domain SH3_2 PF07653.17 CRK15302.1 - 0.0032 17.1 0.0 0.0071 16.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PH_11 PF15413.6 CRK15302.1 - 0.0049 17.3 0.2 0.011 16.2 0.2 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain SAM_1 PF00536.30 CRK15302.1 - 0.056 13.9 0.0 0.11 13.0 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) PH_8 PF15409.6 CRK15302.1 - 0.18 12.1 0.0 0.91 9.9 0.0 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain HAD_2 PF13419.6 CRK15303.1 - 0.019 15.1 0.0 0.043 13.9 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Ribosomal_L5e PF17144.4 CRK15304.1 - 4.1e-81 270.8 0.1 6.7e-81 270.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 CRK15304.1 - 7.8e-35 119.7 7.8 7.8e-35 119.7 7.8 2.0 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region LRR_6 PF13516.6 CRK15305.1 - 0.074 13.1 0.1 0.074 13.1 0.1 5.4 6 0 0 6 6 6 0 Leucine Rich repeat DUF2992 PF11208.8 CRK15305.1 - 1.4 9.1 16.4 3.7 7.8 16.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) Med19 PF10278.9 CRK15305.1 - 2.8 7.8 15.5 5.6 6.9 15.5 1.5 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 RR_TM4-6 PF06459.12 CRK15305.1 - 4 7.2 15.8 7.7 6.2 15.8 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MFS_1 PF07690.16 CRK15307.1 - 9.6e-20 70.8 23.5 9.6e-20 70.8 23.5 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily CENP-B_N PF04218.13 CRK15307.1 - 0.029 14.0 0.0 0.06 13.0 0.0 1.4 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain TMEM132D_C PF15706.5 CRK15307.1 - 0.17 11.6 0.1 0.52 10.1 0.1 1.7 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term DUF2109 PF09882.9 CRK15307.1 - 7.2 6.7 8.1 9 6.4 0.0 3.8 4 0 0 4 4 4 0 Predicted membrane protein (DUF2109) PS_Dcarbxylase PF02666.15 CRK15309.1 - 3.3e-57 193.3 0.0 5.7e-57 192.5 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 CRK15309.1 - 1.7e-38 131.0 0.1 1.8e-18 66.7 0.0 2.6 2 0 0 2 2 2 2 C2 domain EF-hand_6 PF13405.6 CRK15309.1 - 0.012 15.5 0.0 0.082 12.9 0.0 2.5 1 0 0 1 1 1 0 EF-hand domain EF-hand_1 PF00036.32 CRK15309.1 - 0.013 15.0 0.0 0.047 13.2 0.0 2.1 1 0 0 1 1 1 0 EF hand EF-hand_5 PF13202.6 CRK15309.1 - 0.014 14.8 0.0 0.043 13.3 0.0 1.9 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.6 CRK15309.1 - 0.033 14.6 0.2 0.13 12.8 0.2 2.0 1 0 0 1 1 1 0 EF-hand domain pair ERp29 PF07749.12 CRK15309.1 - 0.6 11.0 2.1 2.4 9.1 0.3 2.7 2 1 0 3 3 3 0 Endoplasmic reticulum protein ERp29, C-terminal domain Coatomer_E PF04733.14 CRK15310.1 - 5.3e-61 206.6 7.0 6.4e-61 206.3 7.0 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.6 CRK15310.1 - 5.2e-10 39.7 16.1 0.00057 20.3 1.3 3.7 4 0 0 4 4 3 3 Tetratricopeptide repeat ANAPC3 PF12895.7 CRK15310.1 - 1.3e-06 28.5 0.7 0.2 11.9 0.0 3.5 2 1 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 CRK15310.1 - 0.00019 21.4 0.5 2.3 8.7 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CRK15310.1 - 0.00083 19.6 13.2 0.053 13.8 0.3 5.4 3 2 2 6 6 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 CRK15310.1 - 0.0017 18.1 1.4 0.9 9.5 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 CRK15310.1 - 0.0024 18.6 15.8 0.01 16.6 0.4 5.4 6 2 1 7 7 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 CRK15310.1 - 0.0035 17.9 4.3 2.5 8.9 0.2 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 CRK15310.1 - 0.022 14.9 12.1 0.072 13.2 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 CRK15310.1 - 0.023 15.3 16.1 0.24 12.1 0.3 5.9 6 1 0 6 6 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 CRK15310.1 - 0.055 13.2 5.9 0.18 11.5 0.2 3.7 4 0 0 4 4 4 0 TPR repeat TPR_16 PF13432.6 CRK15310.1 - 0.09 13.4 12.8 0.64 10.7 0.2 4.1 3 1 2 5 5 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 CRK15310.1 - 0.15 12.3 4.6 0.66 10.2 0.3 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 CRK15310.1 - 0.66 10.1 7.9 46 4.4 0.1 5.0 6 1 1 7 7 7 0 Tetratricopeptide repeat McyA_C PF12593.8 CRK15311.1 - 0.2 11.5 0.6 26 4.7 0.1 2.6 2 0 0 2 2 2 0 Microcystin synthetase C terminal MSA-2c PF12238.8 CRK15311.1 - 0.55 10.2 7.5 0.8 9.7 6.9 1.6 1 1 0 1 1 1 0 Merozoite surface antigen 2c MFS_MOT1 PF16983.5 CRK15312.1 - 8.6e-62 206.4 25.5 2.7e-35 121.1 10.1 2.8 2 0 0 2 2 2 2 Molybdate transporter of MFS superfamily Forkhead PF00250.18 CRK15312.1 - 5.7e-12 45.7 0.0 1.6e-11 44.3 0.0 1.8 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 CRK15312.1 - 1.6e-05 25.2 0.1 3.2e-05 24.2 0.1 1.5 1 0 0 1 1 1 1 FHA domain Sulfate_transp PF00916.20 CRK15312.1 - 0.00023 20.1 0.9 0.00023 20.1 0.9 2.1 2 0 0 2 2 2 1 Sulfate permease family DUF3099 PF11298.8 CRK15313.1 - 0.037 14.1 1.2 0.054 13.6 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3099) DUF4234 PF14018.6 CRK15314.1 - 0.013 15.6 0.1 0.21 11.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) LapA_dom PF06305.11 CRK15314.1 - 0.11 12.3 0.8 0.35 10.7 0.8 1.8 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF4386 PF14329.6 CRK15314.1 - 0.12 12.2 7.4 0.24 11.2 0.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4386) Adeno_E3B PF03376.14 CRK15314.1 - 0.16 12.2 0.4 2.1 8.6 0.1 2.4 2 0 0 2 2 2 0 Adenovirus E3B protein MCM PF00493.23 CRK15315.1 - 6.4e-99 329.6 1.4 6.5e-99 329.6 0.0 1.7 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 CRK15315.1 - 8.5e-39 132.3 0.2 1.6e-38 131.4 0.2 1.4 1 0 0 1 1 1 1 MCM OB domain MCM2_N PF12619.8 CRK15315.1 - 3.4e-34 118.3 33.9 3.4e-34 118.3 33.9 3.0 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_lid PF17855.1 CRK15315.1 - 2.2e-24 85.7 0.5 1.3e-23 83.2 0.6 2.3 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 CRK15315.1 - 1.9e-15 57.3 0.1 5e-15 56.0 0.1 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 CRK15315.1 - 1e-07 31.6 0.0 6e-06 25.8 0.0 2.6 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CRK15315.1 - 6.8e-06 26.1 0.0 1.4e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 CRK15315.1 - 0.0029 17.5 0.1 0.016 15.1 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CRK15315.1 - 0.0052 16.5 0.2 0.035 13.8 0.2 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain Zn_ribbon_2 PF12674.7 CRK15315.1 - 0.14 12.8 0.4 0.39 11.4 0.4 1.8 1 0 0 1 1 1 0 Putative zinc ribbon domain zf-TFIIB PF13453.6 CRK15315.1 - 0.39 10.1 1.9 0.87 9.0 1.9 1.6 1 0 0 1 1 1 0 Transcription factor zinc-finger zf-UBR PF02207.20 CRK15316.1 - 1.7e-14 53.8 5.3 1.7e-14 53.8 5.3 2.7 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) AA_permease PF00324.21 CRK15317.1 - 4.9e-99 332.1 36.6 5.6e-99 331.9 36.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CRK15317.1 - 3.1e-32 112.0 40.2 3.8e-32 111.6 40.2 1.0 1 0 0 1 1 1 1 Amino acid permease Fst_toxin PF13955.6 CRK15317.1 - 0.33 10.9 4.6 1.3 9.0 4.6 2.1 1 0 0 1 1 1 0 Toxin Fst, type I toxin-antitoxin system MRP-S28 PF10213.9 CRK15319.1 - 7.6e-47 158.9 0.1 1.3e-46 158.2 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein Metal_resist PF13801.6 CRK15319.1 - 0.2 11.8 3.4 2.2 8.5 0.1 3.4 4 0 0 4 4 4 0 Heavy-metal resistance Aldedh PF00171.22 CRK15320.1 - 1e-76 258.3 0.0 1.4e-76 257.9 0.0 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family UTP25 PF06862.12 CRK15321.1 - 1.3e-205 683.6 0.0 3.5e-125 418.5 0.0 2.1 2 0 0 2 2 2 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 SUZ PF12752.7 CRK15321.1 - 2.2e-13 50.7 0.7 1.5e-12 48.1 0.7 2.5 1 0 0 1 1 1 1 SUZ domain R3H PF01424.22 CRK15321.1 - 6.5e-08 32.5 0.2 2.2e-07 30.8 0.2 1.9 1 0 0 1 1 1 1 R3H domain DEAD PF00270.29 CRK15321.1 - 0.0006 19.6 0.0 0.28 11.0 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Rad1 PF02144.16 CRK15322.1 - 3.6e-57 193.5 0.0 4e-57 193.4 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Thiolase_N PF00108.23 CRK15347.1 - 3.6e-16 59.3 0.6 1.9e-15 56.9 0.6 1.9 1 1 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 CRK15347.1 - 5.1e-08 32.7 0.4 7.2e-06 25.8 0.1 2.4 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 CRK15347.1 - 0.0003 20.5 0.0 0.00069 19.3 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.11 CRK15347.1 - 0.035 12.8 0.2 0.06 12.0 0.2 1.3 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) DFP PF04127.15 CRK15347.1 - 0.13 12.1 0.0 0.61 9.9 0.0 1.9 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein SE PF08491.10 CRK15363.1 - 1.2e-55 188.5 0.0 1.5e-55 188.3 0.0 1.0 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 CRK15363.1 - 0.011 14.9 0.1 0.016 14.5 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain CTP_transf_like PF01467.26 CRK15364.1 - 0.0044 17.2 0.8 0.064 13.5 0.1 2.1 1 1 0 2 2 2 2 Cytidylyltransferase-like Annexin PF00191.20 CRK15365.1 - 1.7e-43 146.5 0.9 3.2e-15 56.0 0.1 3.2 3 0 0 3 3 3 3 Annexin DUF3334 PF11813.8 CRK15365.1 - 0.13 11.9 0.0 0.5 10.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3334) Hema_stalk PF08720.10 CRK15365.1 - 0.15 11.8 0.1 0.32 10.7 0.1 1.5 1 1 0 1 1 1 0 Influenza C hemagglutinin stalk DUF2019 PF09450.10 CRK15365.1 - 0.28 11.2 3.5 0.28 11.1 0.5 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF2019) NOP5NT PF08156.13 CRK15370.1 - 9e-19 67.6 0.2 2.1e-18 66.5 0.2 1.7 1 0 0 1 1 1 1 NOP5NT (NUC127) domain Nop PF01798.18 CRK15370.1 - 1.3e-15 57.5 0.0 2.1e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin DUF772 PF05598.11 CRK15370.1 - 0.043 13.8 0.0 0.94 9.5 0.0 2.7 3 0 0 3 3 3 0 Transposase domain (DUF772) vATP-synt_AC39 PF01992.16 CRK15371.1 - 4.4e-72 243.4 0.0 4.9e-72 243.3 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit COX15-CtaA PF02628.15 CRK15372.1 - 1.4e-56 191.9 6.0 1.8e-56 191.6 6.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Phosphodiest PF01663.22 CRK15373.1 - 3.4e-15 56.5 0.1 4e-15 56.3 0.1 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase RRM_1 PF00076.22 CRK15373.1 - 3.7e-06 26.6 0.0 7.4e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Metalloenzyme PF01676.18 CRK15373.1 - 2.1e-05 24.0 0.1 3.6e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 CRK15373.1 - 0.002 17.6 0.1 0.004 16.6 0.0 1.6 2 0 0 2 2 2 1 Sulfatase RRM_3 PF08777.11 CRK15373.1 - 0.031 14.3 0.1 0.073 13.1 0.1 1.6 1 0 0 1 1 1 0 RNA binding motif DUF229 PF02995.17 CRK15373.1 - 0.056 12.1 0.0 0.079 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) AICARFT_IMPCHas PF01808.18 CRK15375.1 - 1.2e-24 87.3 0.0 1.6e-24 86.9 0.0 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme GTP_EFTU PF00009.27 CRK15375.1 - 0.0015 18.1 0.1 0.0027 17.3 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 CRK15375.1 - 0.095 12.8 0.0 0.33 11.0 0.0 1.9 2 0 0 2 2 2 0 Dynamin family Glyco_transf_28 PF03033.20 CRK15377.1 - 4.6e-21 75.3 0.5 1.4e-12 47.8 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase family 28 N-terminal domain PAF-AH_p_II PF03403.13 CRK15378.1 - 5.6e-35 120.6 0.0 2.5e-23 82.2 0.0 4.3 2 1 2 4 4 4 4 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 CRK15378.1 - 2.8e-06 26.5 0.0 6.5e-06 25.3 0.0 1.6 2 0 0 2 2 2 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 CRK15378.1 - 0.00044 19.4 0.0 0.00081 18.5 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase Hydrolase_4 PF12146.8 CRK15378.1 - 0.013 14.8 0.1 0.13 11.6 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Pkinase_Tyr PF07714.17 CRK15379.1 - 1.6e-05 24.3 0.0 1.1 8.5 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 CRK15379.1 - 0.00037 19.9 0.0 0.077 12.3 0.0 2.8 3 0 0 3 3 3 2 Protein kinase domain Aldo_ket_red PF00248.21 CRK15381.1 - 2.8e-40 138.4 0.0 3.5e-40 138.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family LRR_4 PF12799.7 CRK15382.1 - 7.1e-39 131.2 30.4 5.1e-08 33.1 0.0 6.5 1 1 7 9 9 9 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CRK15382.1 - 4.7e-23 80.7 15.1 9.1e-08 31.7 2.0 5.1 1 1 4 6 6 6 6 Leucine rich repeat LRR_9 PF14580.6 CRK15382.1 - 3.5e-16 59.2 7.0 1.9e-06 27.5 0.6 3.5 1 1 2 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 CRK15382.1 - 1.1e-06 28.2 14.8 0.017 15.2 0.2 7.3 8 0 0 8 8 8 2 Leucine Rich repeat LRR_1 PF00560.33 CRK15382.1 - 0.00086 19.5 15.2 31 5.6 0.3 8.0 8 1 0 8 8 8 1 Leucine Rich Repeat Abhydrolase_1 PF00561.20 CRK15383.1 - 0.0039 16.9 0.0 0.38 10.4 0.0 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CRK15383.1 - 0.0072 15.6 0.0 0.065 12.5 0.0 2.0 1 1 1 2 2 2 1 Serine aminopeptidase, S33 RloB PF13707.6 CRK15384.1 - 0.0081 16.4 0.1 0.015 15.5 0.1 1.4 1 1 0 1 1 1 1 RloB-like protein Ribosomal_L18A PF01775.17 CRK15385.1 - 8.2e-54 180.9 0.5 1e-53 180.6 0.5 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Fungal_trans PF04082.18 CRK15386.1 - 1.6e-15 56.9 0.1 2.9e-15 56.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK15386.1 - 6.1e-08 32.7 13.1 9.3e-08 32.1 13.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acetyltransf_3 PF13302.7 CRK15387.1 - 2.2e-30 106.2 0.0 3.1e-30 105.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CRK15387.1 - 0.015 15.5 0.0 0.64 10.3 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family MFS_1 PF07690.16 CRK15389.1 - 4.2e-33 114.7 52.9 4.2e-33 114.7 52.9 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 CRK15389.1 - 2e-15 56.2 26.4 2.8e-15 55.8 26.4 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 CRK15389.1 - 2.1e-12 46.7 17.2 2.1e-12 46.7 17.2 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter Fungal_trans_2 PF11951.8 CRK15390.1 - 7.3e-06 25.0 0.6 0.0011 17.9 0.0 2.6 3 0 0 3 3 3 2 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK15390.1 - 4.6e-05 23.5 9.7 7.8e-05 22.7 9.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SR-25 PF10500.9 CRK15390.1 - 0.87 9.1 7.8 1.5 8.4 7.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ANAPC_CDC26 PF10471.9 CRK15391.1 - 1.8e-08 35.1 21.0 1.8e-08 35.1 21.0 3.0 1 1 1 2 2 2 1 Anaphase-promoting complex APC subunit CDC26 Velvet PF11754.8 CRK15391.1 - 0.059 13.3 11.5 0.089 12.7 11.5 1.3 1 0 0 1 1 1 0 Velvet factor TFIIA PF03153.13 CRK15391.1 - 0.13 12.2 23.9 0.15 12.0 23.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 CRK15391.1 - 0.13 11.0 8.5 0.14 10.9 8.5 1.1 1 0 0 1 1 1 0 Presenilin Hydin_ADK PF17213.3 CRK15391.1 - 1.6 9.0 9.8 1.9 8.7 9.8 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Endostatin PF06482.11 CRK15391.1 - 2.9 7.3 9.5 3.6 7.0 9.5 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin DUF4407 PF14362.6 CRK15391.1 - 3.2 7.0 11.6 4.2 6.6 11.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GREB1 PF15782.5 CRK15391.1 - 4.4 4.3 11.9 5.1 4.1 11.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Rtf2 PF04641.12 CRK15391.1 - 5.7 6.2 7.8 8.4 5.7 7.8 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger Rad1 PF02144.16 CRK15394.1 - 6.1e-72 242.0 0.0 7e-72 241.8 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Bromodomain PF00439.25 CRK15395.1 - 8.6e-24 83.4 0.6 1.7e-23 82.5 0.6 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 CRK15395.1 - 6.1e-08 32.9 0.1 1.2e-07 32.0 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CRK15395.1 - 6.7e-07 29.3 0.2 1.8e-06 27.9 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CRK15395.1 - 0.00029 21.2 0.1 0.00062 20.1 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Ost5 PF05251.12 CRK15396.1 - 0.00014 22.1 0.3 0.00017 21.8 0.3 1.2 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 Rad1 PF02144.16 CRK15400.1 - 1.1e-13 51.0 0.0 1.2e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Bromodomain PF00439.25 CRK15401.1 - 1.7e-24 85.7 0.6 2.5e-24 85.1 0.6 1.2 1 0 0 1 1 1 1 Bromodomain DUF1656 PF07869.12 CRK15402.1 - 0.19 11.8 3.5 0.32 11.0 3.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) DUF726 PF05277.12 CRK15403.1 - 7e-119 396.7 0.4 1e-118 396.2 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Thioesterase PF00975.20 CRK15403.1 - 0.0073 16.5 0.7 0.033 14.3 0.0 2.1 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_6 PF12697.7 CRK15403.1 - 0.0094 16.6 0.0 0.022 15.3 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family PE-PPE PF08237.11 CRK15403.1 - 0.01 15.4 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain DUF900 PF05990.12 CRK15403.1 - 0.068 12.7 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF726 PF05277.12 CRK15404.1 - 4.3e-119 397.4 0.3 6.6e-119 396.8 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Noc2 PF03715.13 CRK15404.1 - 1.9e-95 319.6 0.0 2.8e-95 319.0 0.0 1.2 1 0 0 1 1 1 1 Noc2p family Thioesterase PF00975.20 CRK15404.1 - 0.0088 16.2 0.3 0.063 13.4 0.0 2.3 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_6 PF12697.7 CRK15404.1 - 0.033 14.8 1.6 0.18 12.3 0.0 2.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family PE-PPE PF08237.11 CRK15404.1 - 0.057 13.0 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain DUF900 PF05990.12 CRK15404.1 - 0.16 11.5 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF1656 PF07869.12 CRK15404.1 - 0.67 10.0 3.5 1.6 8.8 3.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) Noc2 PF03715.13 CRK15405.1 - 2.2e-108 362.0 0.1 1.8e-86 290.1 0.0 2.4 1 1 1 2 2 2 2 Noc2p family VPS28 PF03997.12 CRK15406.1 - 2.4e-67 226.3 0.1 2.9e-67 226.0 0.1 1.1 1 0 0 1 1 1 1 VPS28 protein Cpn60_TCP1 PF00118.24 CRK15407.1 - 1.5e-26 93.1 0.0 2.4e-26 92.4 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PIP5K PF01504.18 CRK15407.1 - 7.5e-17 61.4 0.0 4.5e-06 26.1 0.0 3.6 1 1 2 3 3 3 3 Phosphatidylinositol-4-phosphate 5-Kinase FYVE PF01363.21 CRK15407.1 - 4.1e-14 52.5 9.1 1e-13 51.2 9.1 1.7 1 0 0 1 1 1 1 FYVE zinc finger MMM1 PF10296.9 CRK15407.1 - 2.6e-06 26.7 0.0 0.0076 15.3 0.0 2.8 2 0 0 2 2 2 2 Maintenance of mitochondrial morphology protein 1 LHH PF14411.6 CRK15407.1 - 0.17 12.1 0.4 0.56 10.4 0.4 1.9 1 0 0 1 1 1 0 A nuclease of the HNH/ENDO VII superfamily with conserved LHH FYVE_2 PF02318.16 CRK15407.1 - 1.1 9.5 4.9 2.8 8.2 4.9 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger C1_2 PF03107.16 CRK15407.1 - 6.1 7.2 11.6 3.8 7.9 8.5 2.2 2 0 0 2 2 2 0 C1 domain BolA PF01722.18 CRK15409.1 - 1e-30 105.8 1.9 1.5e-30 105.2 1.9 1.3 1 0 0 1 1 1 1 BolA-like protein NTP_transf_6 PF06042.11 CRK15409.1 - 0.099 12.5 0.1 0.14 12.0 0.1 1.6 1 1 0 1 1 1 0 Nucleotidyltransferase AMP-binding PF00501.28 CRK15410.1 - 5.3e-73 246.0 0.0 6.7e-73 245.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CRK15410.1 - 3.4e-11 43.9 0.1 9.5e-11 42.5 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain IF4E PF01652.18 CRK15411.1 - 4.4e-54 182.6 0.1 5.5e-54 182.3 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E HSP70 PF00012.20 CRK15413.1 - 2.8e-225 749.1 17.3 7.9e-210 698.1 2.5 2.0 1 1 1 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 CRK15413.1 - 8.8e-17 60.9 0.4 7.7e-16 57.8 0.1 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 CRK15413.1 - 0.00056 19.7 0.0 0.0021 17.8 0.0 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Peptidase_M16 PF00675.20 CRK15413.1 - 0.29 11.1 1.9 8.1 6.4 0.7 2.6 2 0 0 2 2 2 0 Insulinase (Peptidase family M16) Lipoprotein_17 PF04200.12 CRK15413.1 - 1.5 9.2 6.5 45 4.5 3.3 4.2 3 1 1 4 4 4 0 Lipoprotein associated domain BACON PF13004.7 CRK15413.1 - 2.9 8.0 12.5 3.5 7.7 1.0 3.1 2 1 1 3 3 3 0 Putative binding domain, N-terminal DUF4042 PF13251.6 CRK15414.1 - 0.00072 19.3 0.0 0.001 18.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4042) DUF1281 PF06924.11 CRK15414.1 - 0.031 13.8 0.1 0.038 13.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1281) RecG_N PF17190.4 CRK15414.1 - 0.096 13.4 0.1 0.12 13.2 0.1 1.2 1 0 0 1 1 1 0 RecG N-terminal helical domain Trep_Strep PF09605.10 CRK15414.1 - 0.1 12.6 0.0 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 Hypothetical bacterial integral membrane protein (Trep_Strep) Dioxygenase_C PF00775.21 CRK15415.1 - 0.00043 19.8 0.1 0.004 16.6 0.1 2.1 1 1 0 1 1 1 1 Dioxygenase PmoA PF14100.6 CRK15417.1 - 0.041 13.4 0.0 0.063 12.8 0.0 1.2 1 0 0 1 1 1 0 Methane oxygenase PmoA MFS_1 PF07690.16 CRK15418.1 - 1.4e-29 103.2 41.4 1.4e-29 103.2 41.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Root_cap PF06830.11 CRK15418.1 - 0.049 13.7 0.6 0.11 12.7 0.6 1.5 1 0 0 1 1 1 0 Root cap Chorion_2 PF03964.15 CRK15418.1 - 0.61 10.9 4.5 1.3 9.9 4.5 1.5 1 0 0 1 1 1 0 Chorion family 2 Pkinase PF00069.25 CRK15419.1 - 4.1e-14 52.6 0.0 1.3e-13 50.9 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK15419.1 - 0.00068 19.0 0.0 0.0013 18.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CRK15419.1 - 0.08 12.3 0.2 0.26 10.6 0.1 1.9 1 1 1 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Bcl-2 PF00452.19 CRK15421.1 - 0.1 13.3 0.2 0.6 10.8 0.1 2.2 2 0 0 2 2 2 0 Apoptosis regulator proteins, Bcl-2 family Glyco_hydro_114 PF03537.13 CRK15423.1 - 1.8e-43 148.5 2.1 2.5e-43 148.1 2.1 1.2 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 MGC-24 PF05283.11 CRK15424.1 - 0.39 11.2 2.5 0.55 10.7 2.5 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Helicase_C PF00271.31 CRK15430.1 - 1.9e-31 108.7 0.0 3.3e-31 107.9 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain fragilysinNterm PF16376.5 CRK15430.1 - 0.025 14.3 0.1 0.091 12.5 0.0 1.8 2 0 0 2 2 2 0 N-terminal domain of fragilysin tRNA-synt_1b PF00579.25 CRK15430.1 - 0.049 12.9 0.1 0.16 11.3 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) Patatin PF01734.22 CRK15445.1 - 1.6e-10 41.5 0.5 2.3e-10 41.0 0.5 1.5 1 1 0 1 1 1 1 Patatin-like phospholipase Sec63 PF02889.16 CRK15445.1 - 0.0041 16.3 0.0 0.006 15.8 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain RRN3 PF05327.11 CRK15445.1 - 2.4 6.6 3.9 3.3 6.1 3.9 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 NOA36 PF06524.12 CRK15445.1 - 3.2 7.0 7.3 4.2 6.6 7.3 1.1 1 0 0 1 1 1 0 NOA36 protein ICL PF00463.21 CRK15462.1 - 3.4e-110 369.0 0.0 3.8e-110 368.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 CRK15462.1 - 2.5e-12 46.7 0.1 4.6e-11 42.6 0.0 2.0 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase DUF2458 PF10454.9 CRK15462.1 - 0.029 14.0 0.1 0.055 13.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) DEAD PF00270.29 CRK15463.1 - 0.00018 21.4 0.0 0.00024 20.9 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Mac PF12464.8 CRK15464.1 - 4.8e-12 45.9 0.0 8.4e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 Maltose acetyltransferase GDP_Man_Dehyd PF16363.5 CRK15465.1 - 1.5e-62 211.9 0.0 1.9e-62 211.6 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CRK15465.1 - 7.2e-51 173.0 0.0 9.5e-51 172.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 CRK15465.1 - 1.4e-21 76.9 0.0 1.6e-20 73.4 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 CRK15465.1 - 1.3e-17 63.8 0.0 1.6e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 CRK15465.1 - 3.1e-17 62.6 0.0 4.6e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 CRK15465.1 - 1.3e-15 57.2 0.0 1.8e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 CRK15465.1 - 3e-08 33.8 0.0 7.9e-08 32.4 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding adh_short PF00106.25 CRK15465.1 - 0.085 12.3 0.1 1.3 8.5 0.1 2.3 2 0 0 2 2 2 0 short chain dehydrogenase ATP-grasp_2 PF08442.10 CRK15467.1 - 5e-48 163.3 0.1 7.9e-48 162.7 0.1 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 CRK15467.1 - 1.6e-24 86.5 1.5 3.2e-24 85.5 1.5 1.5 1 0 0 1 1 1 1 CoA-ligase OKR_DC_1_N PF03709.15 CRK15467.1 - 0.018 15.3 0.4 0.58 10.5 0.1 2.5 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, N-terminal domain RHD3 PF05879.12 CRK15468.1 - 2.8e-49 168.0 0.0 3e-49 167.9 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) Ribosomal_L12_N PF16320.5 CRK15469.1 - 4.1e-07 29.6 1.8 4.1e-07 29.6 1.8 1.8 2 0 0 2 2 2 1 Ribosomal protein L7/L12 dimerisation domain Suf PF05843.14 CRK15472.1 - 2e-12 47.7 0.1 2e-12 47.7 0.1 2.8 4 0 0 4 4 4 1 Suppressor of forked protein (Suf) Nha1_C PF08619.10 CRK15474.1 - 6.8e-83 279.4 23.0 5.7e-72 243.4 8.3 2.0 1 1 1 2 2 2 2 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.21 CRK15474.1 - 9.2e-75 251.8 26.6 1.1e-74 251.5 26.6 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Cofilin_ADF PF00241.20 CRK15475.1 - 0.018 14.8 0.0 0.043 13.6 0.0 1.6 1 0 0 1 1 1 0 Cofilin/tropomyosin-type actin-binding protein Ran_BP1 PF00638.18 CRK15477.1 - 1.2e-48 164.4 1.8 1.9e-48 163.7 0.5 1.9 1 1 1 2 2 2 1 RanBP1 domain YEATS PF03366.16 CRK15477.1 - 3.4e-20 71.8 0.3 6.7e-20 70.9 0.3 1.5 1 0 0 1 1 1 1 YEATS family WH1 PF00568.23 CRK15477.1 - 0.011 15.7 0.1 0.045 13.7 0.1 2.0 1 1 0 1 1 1 0 WH1 domain BET PF17035.5 CRK15477.1 - 0.024 14.8 0.1 0.1 12.8 0.0 2.0 2 0 0 2 2 2 0 Bromodomain extra-terminal - transcription regulation ASFV_J13L PF05568.11 CRK15477.1 - 0.35 10.6 3.8 0.3 10.8 1.9 1.8 2 0 0 2 2 2 0 African swine fever virus J13L protein Phasin PF05597.11 CRK15478.1 - 0.015 15.3 0.1 0.036 14.0 0.1 1.6 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) ASFV_J13L PF05568.11 CRK15478.1 - 0.55 10.0 4.6 1.2 8.9 4.6 1.5 1 0 0 1 1 1 0 African swine fever virus J13L protein Phosducin PF02114.16 CRK15479.1 - 6.4e-09 35.1 0.0 4.7e-08 32.3 0.0 2.1 1 1 0 1 1 1 1 Phosducin Citrate_bind PF16114.5 CRK15479.1 - 0.19 11.2 0.0 0.35 10.3 0.0 1.4 1 0 0 1 1 1 0 ATP citrate lyase citrate-binding WD40 PF00400.32 CRK15480.1 - 8.7e-38 127.7 19.6 3.1e-07 31.0 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK15480.1 - 5.9e-14 52.1 0.1 0.00028 21.1 0.1 4.7 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CRK15480.1 - 0.00011 21.3 0.1 0.37 9.7 0.0 3.8 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 CRK15480.1 - 0.0002 21.3 0.0 0.18 11.7 0.0 2.6 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 CRK15480.1 - 0.0012 18.3 0.0 0.086 12.2 0.0 2.9 1 1 1 2 2 2 2 WD40-like domain Pyr_redox_2 PF07992.14 CRK15482.1 - 1.2e-91 307.1 1.9 1.5e-50 172.1 0.1 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CRK15482.1 - 7e-25 87.4 0.1 2.5e-10 40.7 0.0 3.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase WD40 PF00400.32 CRK15482.1 - 2.6e-09 37.6 0.5 0.0001 23.0 0.1 3.3 2 0 0 2 2 2 2 WD domain, G-beta repeat Pyr_redox_3 PF13738.6 CRK15482.1 - 1.1e-06 28.2 0.2 7.5 5.7 0.0 4.3 4 0 0 4 4 4 4 Pyridine nucleotide-disulphide oxidoreductase EcoR124_C PF12008.8 CRK15482.1 - 2.8e-05 23.9 0.3 0.3 10.7 0.1 2.4 2 0 0 2 2 2 2 Type I restriction and modification enzyme - subunit R C terminal ANAPC4_WD40 PF12894.7 CRK15482.1 - 0.00021 21.5 0.1 0.0018 18.5 0.1 2.4 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain TetR_C_19 PF17924.1 CRK15482.1 - 0.0089 16.6 0.2 31 5.2 0.0 3.7 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain CdhC PF03598.15 CRK15482.1 - 0.017 15.0 0.5 6.2 6.7 0.1 2.5 2 0 0 2 2 2 0 CO dehydrogenase/acetyl-CoA synthase complex beta subunit CBM_2 PF00553.19 CRK15482.1 - 0.043 14.1 2.4 14 6.1 0.1 3.1 3 0 0 3 3 3 0 Cellulose binding domain DUF1836 PF08876.11 CRK15482.1 - 0.06 13.4 1.6 12 6.0 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1836) NAD_binding_8 PF13450.6 CRK15482.1 - 0.082 13.1 0.0 56 4.1 0.0 3.5 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain T6SS_VipA PF05591.12 CRK15482.1 - 3.6 7.4 5.0 12 5.7 0.0 3.6 5 0 0 5 5 5 0 Type VI secretion system, VipA, VC_A0107 or Hcp2 FlaC_arch PF05377.11 CRK15482.1 - 6.9 7.1 6.6 45 4.5 0.4 3.6 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF3311 PF11755.8 CRK15483.1 - 0.00087 19.2 1.0 1.4 8.9 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3311) Ni_hydr_CYTB PF01292.20 CRK15483.1 - 0.0014 18.3 0.0 1.7 8.2 0.0 2.2 2 0 0 2 2 2 2 Prokaryotic cytochrome b561 NicO PF03824.16 CRK15483.1 - 0.0019 17.6 0.0 2 7.7 0.0 2.1 2 0 0 2 2 2 2 High-affinity nickel-transport protein DUF4059 PF13268.6 CRK15483.1 - 0.0037 17.6 0.5 4.4 7.8 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF4059) DUF1180 PF06679.12 CRK15483.1 - 0.02 15.3 0.7 0.02 15.3 0.7 6.0 5 3 1 6 6 4 0 Protein of unknown function (DUF1180) DUF5337 PF17272.2 CRK15483.1 - 0.043 13.7 0.3 13 5.7 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5337) TMEM238 PF15125.6 CRK15483.1 - 0.063 13.5 1.1 14 6.0 0.1 2.2 2 0 0 2 2 2 0 TMEM238 protein family MIG-14_Wnt-bd PF06664.12 CRK15483.1 - 0.099 11.8 0.0 13 4.9 0.0 2.1 2 0 0 2 2 2 0 Wnt-binding factor required for Wnt secretion OPA3 PF07047.12 CRK15483.1 - 0.1 12.4 0.2 19 5.1 0.0 2.2 2 0 0 2 2 2 0 Optic atrophy 3 protein (OPA3) 7TM-7TMR_HD PF07698.11 CRK15483.1 - 0.15 11.8 0.2 21 4.8 0.0 2.2 2 0 0 2 2 2 0 7TM receptor with intracellular HD hydrolase ARL6IP6 PF15062.6 CRK15483.1 - 5.1 7.3 9.7 37 4.5 0.1 3.8 3 0 0 3 3 3 0 Haemopoietic lineage transmembrane helix DUF3716 PF12511.8 CRK15488.1 - 1.1e-15 57.4 12.7 1.5e-07 31.3 2.6 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3716) Exog_C PF18026.1 CRK15488.1 - 5.8e-05 23.1 0.0 6.7 6.9 0.0 3.9 3 0 0 3 3 3 2 Endo/exonuclease (EXOG) C-terminal domain GATase_6 PF13522.6 CRK15488.1 - 0.0014 18.8 0.0 0.89 9.7 0.0 2.8 2 0 0 2 2 2 2 Glutamine amidotransferase domain LytR_cpsA_psr PF03816.14 CRK15488.1 - 0.0032 17.6 0.0 38 4.4 0.0 3.4 3 0 0 3 3 3 0 Cell envelope-related transcriptional attenuator domain VIGSSK PF14773.6 CRK15488.1 - 0.057 13.6 0.3 22 5.3 0.0 3.3 3 0 0 3 3 3 0 Helicase-associated putative binding domain, C-terminal ATP-synt_ab_C PF00306.27 CRK15488.1 - 0.35 11.2 6.6 48 4.3 0.0 3.7 4 0 0 4 4 4 0 ATP synthase alpha/beta chain, C terminal domain CENP-F_N PF10481.9 CRK15488.1 - 0.53 9.9 6.0 6.8 6.2 0.1 2.7 3 0 0 3 3 3 0 Cenp-F N-terminal domain WD40 PF00400.32 CRK15489.1 - 0.51 11.3 3.5 1.6e+02 3.4 0.0 4.4 4 0 0 4 4 4 0 WD domain, G-beta repeat Polysacc_deac_1 PF01522.21 CRK15490.1 - 4.2e-28 97.7 0.0 7.3e-28 96.9 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 CRK15490.1 - 0.0017 17.6 0.0 0.0033 16.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 DUF2334 PF10096.9 CRK15490.1 - 0.058 13.0 0.0 0.084 12.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) Chitin_synth_2 PF03142.15 CRK15491.1 - 3.3e-40 138.2 6.0 2.1e-31 109.1 5.2 2.3 1 1 1 2 2 2 2 Chitin synthase Polysacc_deac_1 PF01522.21 CRK15491.1 - 5.4e-26 90.9 0.0 1.9e-25 89.2 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 CRK15491.1 - 2.9e-08 34.0 41.3 0.00071 20.0 11.1 3.1 2 0 0 2 2 2 2 Chitin recognition protein Glycos_transf_2 PF00535.26 CRK15491.1 - 1.7e-06 28.0 0.0 0.057 13.2 0.0 2.7 3 0 0 3 3 3 2 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 CRK15491.1 - 7.8e-05 22.7 2.2 7.8e-05 22.7 2.2 3.1 2 1 0 2 2 2 1 Glycosyl transferase family group 2 DUF2334 PF10096.9 CRK15491.1 - 0.0019 17.9 0.1 0.0057 16.3 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2334) Glyco_tranf_2_3 PF13641.6 CRK15491.1 - 0.004 17.1 0.1 5.2 6.9 0.0 3.0 3 0 0 3 3 3 2 Glycosyltransferase like family 2 UDPG_MGDP_dh PF00984.19 CRK15492.1 - 1.7e-19 69.8 0.0 4.6e-19 68.4 0.0 1.8 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_N PF03721.14 CRK15492.1 - 6.7e-16 58.4 0.0 1.8e-13 50.5 0.0 2.3 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.15 CRK15492.1 - 2.2e-06 27.9 0.0 4e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_C PF03720.15 CRK15492.1 - 5.8e-05 23.5 0.0 0.00012 22.5 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain TrkA_N PF02254.18 CRK15492.1 - 0.02 15.2 0.0 0.064 13.5 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain F420_oxidored PF03807.17 CRK15492.1 - 0.12 13.0 0.0 0.41 11.2 0.0 1.9 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Ribosomal_L27A PF00828.19 CRK15494.1 - 6.8e-61 204.6 11.5 5.2e-30 104.8 2.1 2.5 2 0 0 2 2 2 2 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Glyco_hydro_16 PF00722.21 CRK15494.1 - 7.1e-44 149.4 4.8 1.2e-43 148.6 4.8 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 PX PF00787.24 CRK15494.1 - 9.4e-13 48.1 0.0 6.7e-05 22.8 0.0 2.5 2 0 0 2 2 2 2 PX domain DUF4777 PF16007.5 CRK15494.1 - 0.013 15.8 0.0 11 6.4 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4777) Chitin_bind_1 PF00187.19 CRK15494.1 - 0.051 14.1 11.3 0.14 12.7 11.3 1.7 1 0 0 1 1 1 0 Chitin recognition protein Fibritin_C PF07921.12 CRK15494.1 - 0.085 13.0 0.0 6.2 7.0 0.0 2.6 2 0 0 2 2 2 0 Fibritin C-terminal region PIN_9 PF18477.1 CRK15494.1 - 0.38 11.1 1.0 4.6 7.6 0.3 2.4 2 0 0 2 2 2 0 PIN like domain DEC-1_C PF04626.13 CRK15494.1 - 4.2 7.8 8.1 24 5.3 0.9 2.7 2 0 0 2 2 2 0 Dec-1 protein, C terminal region Myb_DNA-binding PF00249.31 CRK15495.1 - 3.3e-17 62.4 2.0 7.8e-10 38.8 0.3 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CRK15495.1 - 1.4e-10 41.3 0.5 2.3e-05 24.5 0.0 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain Presenilin PF01080.17 CRK15495.1 - 8.2 5.1 10.2 13 4.4 10.2 1.2 1 0 0 1 1 1 0 Presenilin Myb_DNA-binding PF00249.31 CRK15496.1 - 3.4e-17 62.3 2.0 8e-10 38.8 0.3 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CRK15496.1 - 1.4e-10 41.2 0.6 2.5e-05 24.4 0.0 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain Macoilin PF09726.9 CRK15496.1 - 0.54 8.7 6.6 0.84 8.1 6.6 1.2 1 0 0 1 1 1 0 Macoilin family hSH3 PF14603.6 CRK15497.1 - 0.1 13.0 0.0 0.18 12.3 0.0 1.3 1 0 0 1 1 1 0 Helically-extended SH3 domain ILVD_EDD PF00920.21 CRK15500.1 - 1.1e-50 172.7 0.1 1.4e-50 172.4 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family ILVD_EDD PF00920.21 CRK15501.1 - 2.6e-204 679.7 0.4 3.1e-204 679.4 0.4 1.0 1 0 0 1 1 1 1 Dehydratase family Glyco_transf_15 PF01793.16 CRK15502.1 - 1.2e-93 314.0 7.9 1.5e-92 310.3 7.9 2.0 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase ILVD_EDD PF00920.21 CRK15503.1 - 3.3e-153 511.0 0.1 4.9e-153 510.4 0.1 1.2 1 0 0 1 1 1 1 Dehydratase family Glyco_transf_15 PF01793.16 CRK15503.1 - 2.1e-92 309.8 7.6 1.3e-91 307.2 7.6 1.9 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Prp19 PF08606.11 CRK15503.1 - 1.2e-31 108.5 2.8 2.3e-31 107.6 2.8 1.5 1 0 0 1 1 1 1 Prp19/Pso4-like COX5B PF01215.19 CRK15503.1 - 4.5e-21 74.9 0.0 8.7e-21 74.0 0.0 1.5 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb V_ATPase_I_N PF18670.1 CRK15503.1 - 0.008 16.6 1.9 0.0096 16.3 0.4 1.9 2 0 0 2 2 2 1 V-type ATPase subunit I, N-terminal domain zf-Nse PF11789.8 CRK15503.1 - 0.024 14.4 0.0 0.092 12.6 0.0 1.9 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit OHCU_decarbox PF09349.10 CRK15504.1 - 4.5e-48 163.7 0.1 5.1e-48 163.5 0.1 1.0 1 0 0 1 1 1 1 OHCU decarboxylase DUF4604 PF15377.6 CRK15505.1 - 9.7e-32 110.8 12.8 1.1e-31 110.6 12.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) OHCU_decarbox PF09349.10 CRK15507.1 - 9.9e-48 162.5 0.2 1.1e-47 162.4 0.2 1.0 1 0 0 1 1 1 1 OHCU decarboxylase Prp19 PF08606.11 CRK15508.1 - 2.2e-31 107.6 3.0 2.2e-31 107.6 3.0 1.7 2 0 0 2 2 2 1 Prp19/Pso4-like ANAPC4_WD40 PF12894.7 CRK15508.1 - 3.9e-12 46.3 0.0 0.048 14.0 0.0 4.9 2 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CRK15508.1 - 1.4e-09 38.4 0.7 0.35 11.8 0.0 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat Gmad1 PF10647.9 CRK15508.1 - 4.8e-05 23.3 3.0 0.00026 20.8 1.6 2.4 1 1 0 1 1 1 1 Lipoprotein LpqB beta-propeller domain V_ATPase_I_N PF18670.1 CRK15508.1 - 0.0017 18.7 2.2 0.0041 17.5 0.4 2.4 3 0 0 3 3 3 1 V-type ATPase subunit I, N-terminal domain zf-Nse PF11789.8 CRK15508.1 - 0.0062 16.3 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit VID27 PF08553.10 CRK15508.1 - 0.0095 15.0 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain Lactonase PF10282.9 CRK15508.1 - 0.019 14.2 0.0 0.049 12.9 0.0 1.7 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller Sun2_CC2 PF18580.1 CRK15508.1 - 0.023 14.9 0.2 1.2 9.4 0.0 2.7 2 0 0 2 2 2 0 SUN2 coiled coil domain 2 Frtz PF11768.8 CRK15508.1 - 0.18 10.1 0.0 0.44 8.8 0.0 1.5 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz zf-RING_UBOX PF13445.6 CRK15509.1 - 0.00057 19.9 2.5 0.002 18.1 2.5 1.9 1 1 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 CRK15509.1 - 0.0012 18.6 1.5 0.021 14.6 0.3 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CRK15509.1 - 0.0043 17.0 4.2 0.01 15.8 1.3 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CRK15509.1 - 0.04 13.8 1.3 0.24 11.3 0.3 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CRK15509.1 - 0.056 13.3 1.6 0.19 11.6 1.8 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CRK15509.1 - 0.15 11.9 0.2 0.15 11.9 0.2 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CRK15509.1 - 0.28 11.5 3.0 0.46 10.9 0.5 2.1 2 0 0 2 2 2 0 Ring finger domain Endonuc_Holl PF10107.9 CRK15510.1 - 8.8 6.2 9.6 57 3.5 9.2 2.3 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase CAF1C_H4-bd PF12265.8 CRK15511.1 - 1.8e-06 28.1 0.1 3.2e-06 27.3 0.1 1.4 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex zf-RING_UBOX PF13445.6 CRK15511.1 - 0.00044 20.2 2.1 0.0016 18.4 2.1 2.0 1 1 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 CRK15511.1 - 0.0014 18.4 1.5 0.024 14.5 0.3 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CRK15511.1 - 0.0048 16.8 4.2 0.011 15.6 1.3 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CRK15511.1 - 0.046 13.6 1.3 0.26 11.2 0.3 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CRK15511.1 - 0.048 13.5 1.3 0.17 11.8 1.4 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CRK15511.1 - 0.19 11.6 2.3 0.17 11.8 0.2 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CRK15511.1 - 0.3 11.5 3.0 0.51 10.7 0.5 2.3 2 0 0 2 2 2 0 Ring finger domain WD40 PF00400.32 CRK15513.1 - 2.7e-24 85.0 20.5 7.9e-07 29.7 0.2 7.3 7 0 0 7 7 7 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 CRK15513.1 - 3.8e-18 65.5 0.0 5.6e-11 42.5 0.0 3.2 2 0 0 2 2 2 2 Histone-binding protein RBBP4 or subunit C of CAF1 complex OTT_1508_deam PF14441.6 CRK15513.1 - 1.9e-15 56.6 1.3 1e-14 54.3 0.3 2.4 2 0 0 2 2 2 1 OTT_1508-like deaminase ANAPC4_WD40 PF12894.7 CRK15513.1 - 1.8e-14 53.8 3.8 0.011 16.1 0.1 5.3 5 1 0 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain DUF4705 PF15788.5 CRK15513.1 - 0.00076 19.7 0.6 0.34 11.2 0.0 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4705) Peripla_BP_4 PF13407.6 CRK15513.1 - 0.0032 17.1 0.1 0.63 9.6 0.0 2.4 2 0 0 2 2 2 1 Periplasmic binding protein domain PQQ_3 PF13570.6 CRK15513.1 - 0.0079 16.7 1.4 13 6.5 0.1 3.8 2 0 0 2 2 2 2 PQQ-like domain Nup160 PF11715.8 CRK15513.1 - 0.03 13.0 3.0 3 6.4 0.1 2.7 3 0 0 3 3 3 0 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 CRK15513.1 - 0.32 9.9 2.0 0.27 10.1 0.2 1.7 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain ssDNA_TraI_N PF18272.1 CRK15513.1 - 3.2 7.8 6.8 55 3.9 0.2 4.1 4 0 0 4 4 4 0 single-stranded DNA binding TraI N-terminal subdomain Aldo_ket_red PF00248.21 CRK15514.1 - 6.6e-52 176.5 0.0 4.7e-36 124.5 0.0 3.9 2 2 0 2 2 2 2 Aldo/keto reductase family Dev_Cell_Death PF10539.9 CRK15514.1 - 8.7e-05 22.4 0.0 0.59 10.0 0.0 2.3 2 0 0 2 2 2 2 Development and cell death domain YAcAr PF10686.9 CRK15514.1 - 0.019 14.9 0.4 13 5.8 0.0 3.0 3 0 0 3 3 3 0 YspA, cpYpsA-related SLOG family PROCT PF08084.11 CRK15514.1 - 0.032 14.1 0.1 11 5.9 0.0 2.3 2 0 0 2 2 2 0 PROCT (NUC072) domain Luteo_PO PF04662.13 CRK15514.1 - 0.063 12.9 0.0 13 5.3 0.0 2.2 2 0 0 2 2 2 0 Luteovirus P0 protein PPK2 PF03976.14 CRK15514.1 - 0.11 12.0 0.0 20 4.6 0.0 2.6 2 0 0 2 2 2 0 Polyphosphate kinase 2 (PPK2) VWA_3 PF13768.6 CRK15514.1 - 0.18 11.7 0.0 17 5.3 0.0 2.5 2 0 0 2 2 2 0 von Willebrand factor type A domain Amidoligase_2 PF12224.8 CRK15517.1 - 1e-19 71.2 0.0 8.4e-19 68.2 0.0 1.9 1 1 0 1 1 1 1 Putative amidoligase enzyme RasGAP_C PF03836.15 CRK15518.1 - 0.019 15.1 1.4 0.024 14.8 1.4 1.1 1 0 0 1 1 1 0 RasGAP C-terminus YgaB PF14182.6 CRK15518.1 - 0.032 14.6 1.9 0.038 14.4 1.9 1.1 1 0 0 1 1 1 0 YgaB-like protein ZapD PF07072.11 CRK15518.1 - 0.034 13.9 2.3 0.041 13.6 2.3 1.0 1 0 0 1 1 1 0 Cell division protein Halogen_Hydrol PF10112.9 CRK15518.1 - 0.056 13.5 0.5 0.067 13.2 0.5 1.0 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein YjcZ PF13990.6 CRK15518.1 - 0.074 12.4 0.7 0.09 12.1 0.7 1.0 1 0 0 1 1 1 0 YjcZ-like protein Fzo_mitofusin PF04799.13 CRK15518.1 - 0.35 10.4 3.1 0.44 10.1 3.1 1.0 1 0 0 1 1 1 0 fzo-like conserved region eRF1_1 PF03463.15 CRK15520.1 - 1.3e-41 141.6 0.0 2.2e-41 140.9 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.15 CRK15520.1 - 1.7e-20 73.7 0.1 3.1e-20 72.8 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 CRK15520.1 - 0.0049 17.3 0.0 0.012 16.1 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 3 WD40 PF00400.32 CRK15522.1 - 4.9e-27 93.6 12.3 2e-06 28.4 0.1 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK15522.1 - 5.4e-06 26.6 1.1 0.84 10.0 0.0 4.3 3 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CRK15522.1 - 0.16 10.9 0.6 1.7 7.5 0.0 2.7 3 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Amidoligase_2 PF12224.8 CRK15525.1 - 2.9e-18 66.4 0.0 4.6e-17 62.5 0.0 2.0 1 1 0 1 1 1 1 Putative amidoligase enzyme NAD_binding_4 PF07993.12 CRK15527.1 - 7.2e-40 136.8 0.0 1.8e-39 135.5 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 CRK15527.1 - 1.6e-32 112.6 0.0 2.8e-32 111.9 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 CRK15527.1 - 5.2e-12 45.8 0.0 1.2e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 CRK15527.1 - 6.4e-08 32.8 0.1 1.4e-07 31.7 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site GDP_Man_Dehyd PF16363.5 CRK15527.1 - 0.0033 16.9 0.0 0.17 11.2 0.0 2.2 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 CRK15527.1 - 0.017 14.2 0.0 0.78 8.7 0.0 2.2 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 CRK15527.1 - 0.038 13.9 0.2 0.15 12.0 0.2 2.1 1 1 0 1 1 1 0 KR domain Phage_Coat_Gp8 PF05371.12 CRK15527.1 - 0.23 11.3 1.3 0.83 9.5 0.2 2.3 2 0 0 2 2 2 0 Phage major coat protein, Gp8 NAD_binding_4 PF07993.12 CRK15528.1 - 6.1e-39 133.7 0.0 1.5e-38 132.4 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 CRK15528.1 - 2.6e-33 115.2 0.0 5.1e-33 114.3 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 CRK15528.1 - 3.9e-11 42.9 0.0 8.7e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 CRK15528.1 - 5.4e-08 33.1 0.1 1.4e-07 31.7 0.1 1.8 2 0 0 2 2 2 1 Phosphopantetheine attachment site GDP_Man_Dehyd PF16363.5 CRK15528.1 - 0.0067 15.9 0.0 0.35 10.2 0.0 2.2 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 CRK15528.1 - 0.022 13.8 0.0 1 8.3 0.0 2.2 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 CRK15528.1 - 0.048 13.6 0.1 0.14 12.0 0.1 1.9 1 1 0 1 1 1 0 KR domain Phage_Coat_Gp8 PF05371.12 CRK15528.1 - 0.085 12.6 1.4 0.25 11.1 0.2 2.2 2 0 0 2 2 2 0 Phage major coat protein, Gp8 Fungal_trans PF04082.18 CRK15531.1 - 1.7e-48 165.0 6.4 2e-26 92.6 0.5 2.5 3 0 0 3 3 3 2 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK15531.1 - 2.3e-08 34.0 32.0 1.2e-06 28.5 11.3 3.2 4 0 0 4 4 4 2 Fungal Zn(2)-Cys(6) binuclear cluster domain FF PF01846.19 CRK15531.1 - 0.079 13.1 0.0 21 5.4 0.0 2.4 2 0 0 2 2 2 0 FF domain MR_MLE_C PF13378.6 CRK15533.1 - 1.4e-59 201.4 0.1 1.7e-59 201.1 0.1 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 CRK15533.1 - 4.2e-17 62.4 0.0 8.5e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain DHDPS PF00701.22 CRK15535.1 - 7.3e-05 21.6 0.0 8.7e-05 21.4 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family MR_MLE_C PF13378.6 CRK15537.1 - 1.1e-58 198.4 0.1 1.4e-58 198.1 0.1 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 CRK15537.1 - 4.3e-17 62.4 0.0 8.5e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Aldo_ket_red PF00248.21 CRK15539.1 - 2.5e-100 335.5 0.0 4.3e-53 180.4 0.0 2.7 2 1 0 2 2 2 2 Aldo/keto reductase family RE_AlwI PF09491.10 CRK15539.1 - 0.0091 14.8 0.2 2.8 6.6 0.0 2.1 2 0 0 2 2 2 2 AlwI restriction endonuclease YjcQ PF09639.10 CRK15539.1 - 0.011 16.0 0.0 6.6 7.0 0.0 2.3 2 0 0 2 2 2 0 YjcQ protein MinC_N PF05209.13 CRK15539.1 - 0.028 14.4 0.0 11 6.0 0.0 2.6 2 0 0 2 2 2 0 Septum formation inhibitor MinC, N-terminal domain PALP PF00291.25 CRK15539.1 - 0.033 13.6 0.0 7.9 5.8 0.0 2.4 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme TSNR_N PF04705.12 CRK15539.1 - 0.038 14.1 0.0 16 5.6 0.0 2.7 2 0 0 2 2 2 0 Thiostrepton-resistance methylase, N terminus PucR PF07905.11 CRK15539.1 - 0.044 14.1 0.0 2.8 8.3 0.0 2.6 2 0 0 2 2 2 0 Purine catabolism regulatory protein-like family Jag_N PF14804.6 CRK15539.1 - 0.095 13.1 0.7 29 5.1 0.1 2.9 2 0 0 2 2 2 0 Jag N-terminus DHDPS PF00701.22 CRK15542.1 - 7.4e-43 146.3 0.0 5.3e-23 81.2 0.0 2.0 1 1 1 2 2 2 2 Dihydrodipicolinate synthetase family DUF818 PF05677.12 CRK15542.1 - 0.00047 19.2 0.2 0.9 8.4 0.0 2.3 2 0 0 2 2 2 2 Chlamydia CHLPS protein (DUF818) STALD PF18185.1 CRK15542.1 - 0.0008 18.8 0.0 0.78 9.0 0.0 2.4 2 0 0 2 2 2 2 Sir2- and TIR-associating SLOG family Lipocalin_5 PF13924.6 CRK15542.1 - 0.13 12.0 0.1 22 4.8 0.0 2.3 2 0 0 2 2 2 0 Lipocalin-like domain DHDPS PF00701.22 CRK15544.1 - 2.4e-08 33.0 0.0 2.8e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family STALD PF18185.1 CRK15544.1 - 0.085 12.2 0.0 0.13 11.6 0.0 1.4 1 1 0 1 1 1 0 Sir2- and TIR-associating SLOG family Meth_synt_2 PF01717.18 CRK15546.1 - 0.0036 16.6 0.6 0.0039 16.5 0.6 1.1 1 0 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Dak1 PF02733.17 CRK15547.1 - 4.2e-104 347.8 1.9 5.8e-104 347.3 1.9 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 CRK15547.1 - 1e-46 159.0 7.6 1.4e-46 158.6 6.1 2.0 2 0 0 2 2 2 1 DAK2 domain MFS_1 PF07690.16 CRK15549.1 - 3.7e-41 141.2 18.9 6.2e-41 140.5 18.0 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Rol_Rep_N PF18106.1 CRK15552.1 - 0.036 14.4 0.0 0.036 14.4 0.0 1.1 1 0 0 1 1 1 0 Rolling Circle replication initiation protein N-terminal domain AA_permease PF00324.21 CRK15554.1 - 2.4e-136 455.1 40.3 2.7e-136 455.0 40.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CRK15554.1 - 2.6e-32 112.2 48.2 4.5e-32 111.4 48.0 1.4 1 1 0 1 1 1 1 Amino acid permease Adeno_E3B PF03376.14 CRK15554.1 - 0.28 11.4 2.4 2 8.7 0.0 2.9 2 0 0 2 2 2 0 Adenovirus E3B protein Arrestin_C PF02752.22 CRK15559.1 - 2.3e-29 102.5 0.0 6.7e-13 49.2 0.0 3.4 2 2 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CRK15559.1 - 2.2e-14 53.8 0.6 0.012 15.6 0.1 4.4 4 0 0 4 4 4 4 Arrestin (or S-antigen), N-terminal domain Vfa1 PF08432.10 CRK15559.1 - 0.002 18.5 11.4 0.061 13.6 0.6 2.4 2 0 0 2 2 2 2 AAA-ATPase Vps4-associated protein 1 TAF PF02969.17 CRK15559.1 - 0.016 15.3 8.2 1.2 9.3 1.0 2.5 2 0 0 2 2 2 0 TATA box binding protein associated factor (TAF) FbpC_C_terminal PF17845.1 CRK15559.1 - 0.033 14.3 0.2 15 5.8 0.0 2.5 2 0 0 2 2 2 0 FbpC C-terminal regulatory nucleotide binding domain DDRGK PF09756.9 CRK15559.1 - 0.062 12.9 28.5 0.69 9.5 10.3 2.2 2 0 0 2 2 2 0 DDRGK domain Plug PF07715.15 CRK15559.1 - 0.12 13.0 2.2 5.2 7.7 0.1 2.5 2 0 0 2 2 2 0 TonB-dependent Receptor Plug Domain RXT2_N PF08595.11 CRK15559.1 - 0.21 11.6 9.7 3.1 7.8 1.9 2.6 2 0 0 2 2 2 0 RXT2-like, N-terminal NARP1 PF12569.8 CRK15559.1 - 0.25 10.2 21.4 1.1 8.1 7.4 2.1 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 RR_TM4-6 PF06459.12 CRK15559.1 - 0.37 10.6 10.5 2.4 7.9 1.8 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 LRS4 PF10422.9 CRK15559.1 - 0.61 9.6 20.5 2 7.9 6.0 2.6 2 0 0 2 2 2 0 Monopolin complex subunit LRS4 RNA_pol_3_Rpc31 PF11705.8 CRK15559.1 - 0.69 10.1 19.4 3.9 7.7 6.0 2.5 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 CT47 PF15623.6 CRK15559.1 - 2.1 8.1 13.8 4.8 6.9 2.5 2.4 2 0 0 2 2 2 0 Cancer/testis gene family 47 DUF1682 PF07946.14 CRK15559.1 - 2.2 7.4 33.3 0.42 9.8 10.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) Ribosomal_S8e PF01201.22 CRK15559.1 - 3.8 7.7 20.0 9.7 6.4 5.8 2.5 2 0 0 2 2 2 0 Ribosomal protein S8e ATC_hydrolase PF14196.6 CRK15559.1 - 6.1 7.6 8.9 24 5.7 1.2 2.4 2 0 0 2 2 2 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase TetR_C_23 PF17931.1 CRK15559.1 - 9.6 6.3 10.6 19 5.4 1.7 2.5 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain NUDIX PF00293.28 CRK15563.1 - 8.4e-16 58.2 0.1 1.1e-15 57.8 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 CRK15563.1 - 4.5e-05 23.4 0.1 0.00015 21.7 0.1 1.8 1 1 0 1 1 1 1 NUDIX domain Sun2_CC2 PF18580.1 CRK15569.1 - 0.23 11.7 1.8 0.31 11.3 0.4 2.0 2 0 0 2 2 2 0 SUN2 coiled coil domain 2 PIG-L PF02585.17 CRK15573.1 - 5.9e-26 91.6 0.0 8.6e-26 91.1 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Anophelin PF10731.9 CRK15575.1 - 0.0095 15.8 2.0 0.78 9.6 0.1 2.4 2 0 0 2 2 2 2 Thrombin inhibitor from mosquito LSM PF01423.22 CRK15577.1 - 3.6e-19 68.2 0.1 4.5e-19 67.9 0.1 1.1 1 0 0 1 1 1 1 LSM domain ATP13 PF12921.7 CRK15579.1 - 8.1e-15 54.7 0.0 6.6e-14 51.8 0.0 2.4 2 1 1 3 3 3 1 Mitochondrial ATPase expression GTP_EFTU_D2 PF03144.25 CRK15581.1 - 2e-20 72.9 3.6 1e-08 35.4 0.3 4.0 4 0 0 4 4 4 2 Elongation factor Tu domain 2 GTP_EFTU PF00009.27 CRK15581.1 - 2.3e-18 66.5 0.0 4.3e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LSM PF01423.22 CRK15581.1 - 1.2e-12 47.4 0.1 2.6e-12 46.2 0.1 1.6 1 0 0 1 1 1 1 LSM domain GTP_EFTU_D3 PF03143.17 CRK15581.1 - 1.5e-10 41.4 0.1 0.00068 19.9 0.0 2.9 2 0 0 2 2 2 2 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 CRK15581.1 - 0.00054 20.0 0.1 0.0024 17.9 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 CRK15581.1 - 0.0088 16.3 0.0 0.045 14.0 0.0 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 CRK15581.1 - 0.014 15.3 0.3 5.8 6.8 0.1 2.5 2 0 0 2 2 2 0 RsgA GTPase Ras PF00071.22 CRK15581.1 - 0.053 13.1 0.0 0.28 10.7 0.0 2.1 2 0 0 2 2 2 0 Ras family PduV-EutP PF10662.9 CRK15581.1 - 0.061 13.1 0.3 2.5 7.9 0.1 3.0 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 CRK15581.1 - 0.084 12.9 0.1 0.23 11.5 0.1 1.7 1 0 0 1 1 1 0 Dynamin family Tom22 PF04281.13 CRK15583.1 - 6.3e-35 120.0 0.3 5.6e-32 110.4 0.0 2.4 2 0 0 2 2 2 2 Mitochondrial import receptor subunit Tom22 A_deaminase PF00962.22 CRK15583.1 - 1.5e-21 77.1 0.0 2.5e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase MFS_1 PF07690.16 CRK15583.1 - 2.8e-20 72.6 56.6 2.4e-16 59.6 26.2 4.1 3 2 1 4 4 4 3 Major Facilitator Superfamily DUF3433 PF11915.8 CRK15583.1 - 3e-13 50.0 2.3 3e-13 50.0 2.3 3.7 3 0 0 3 3 3 1 Protein of unknown function (DUF3433) ATP-synt_8 PF00895.20 CRK15583.1 - 1.5 9.3 3.4 24 5.5 0.2 2.7 2 0 0 2 2 2 0 ATP synthase protein 8 ArsP_1 PF03773.13 CRK15588.1 - 0.0077 15.4 0.9 0.013 14.7 0.0 1.6 2 0 0 2 2 2 1 Predicted permease MFS_1 PF07690.16 CRK15590.1 - 6.2e-32 110.9 34.5 9.8e-32 110.2 34.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK15590.1 - 1.3e-08 34.2 12.6 2.7e-08 33.1 12.6 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter RPAP1_N PF08621.10 CRK15590.1 - 0.13 12.0 0.0 2.7 7.9 0.0 2.7 3 0 0 3 3 3 0 RPAP1-like, N-terminal Peptidase_S8 PF00082.22 CRK15592.1 - 7.6e-30 104.2 0.0 3.5e-20 72.4 0.0 2.8 1 1 1 2 2 2 2 Subtilase family fn3_5 PF06280.12 CRK15592.1 - 8.8e-07 29.6 0.0 8.8e-07 29.6 0.0 2.3 2 0 0 2 2 2 1 Fn3-like domain Lip_prot_lig_C PF10437.9 CRK15592.1 - 0.14 12.1 0.0 0.89 9.6 0.0 2.2 2 0 0 2 2 2 0 Bacterial lipoate protein ligase C-terminus AMP-binding PF00501.28 CRK15597.1 - 1.7e-51 175.1 0.0 5.1e-30 104.4 0.0 2.3 1 1 1 2 2 2 2 AMP-binding enzyme PP-binding PF00550.25 CRK15597.1 - 6.7e-11 42.4 0.1 8.2e-10 38.9 0.1 2.4 2 0 0 2 2 2 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 CRK15597.1 - 0.0041 18.0 0.0 1.2 10.2 0.0 2.6 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Hexapep PF00132.24 CRK15597.1 - 0.019 14.6 10.1 0.39 10.5 0.0 4.9 5 0 0 5 5 5 0 Bacterial transferase hexapeptide (six repeats) GH3 PF03321.13 CRK15597.1 - 0.29 9.9 0.0 1.4 7.7 0.0 1.8 2 0 0 2 2 2 0 GH3 auxin-responsive promoter ASL_C2 PF14698.6 CRK15602.1 - 7.6e-15 55.4 1.2 1.1e-14 54.9 0.1 1.9 3 0 0 3 3 3 1 Argininosuccinate lyase C-terminal ADSL_C PF10397.9 CRK15602.1 - 0.0018 18.8 1.5 0.0037 17.8 0.1 2.1 3 0 0 3 3 3 1 Adenylosuccinate lyase C-terminus Glyco_hydro_3_C PF01915.22 CRK15603.1 - 1.8e-49 168.5 0.0 2.8e-49 167.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain DUF3500 PF12006.8 CRK15603.1 - 6.9e-44 150.5 0.0 1.1e-43 149.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) Sugar_tr PF00083.24 CRK15603.1 - 6.6e-40 137.3 7.3 9e-40 136.9 7.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Glyco_hydro_3 PF00933.21 CRK15603.1 - 1.2e-31 110.3 0.0 3e-31 109.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 CRK15603.1 - 4.2e-21 74.8 0.1 8.7e-21 73.8 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain MFS_1 PF07690.16 CRK15603.1 - 2.9e-08 33.1 19.5 5.1e-08 32.2 19.5 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily PA14 PF07691.12 CRK15603.1 - 5.1e-06 26.4 0.0 1e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 PA14 domain BAT PF15915.5 CRK15603.1 - 0.099 12.5 0.8 0.28 11.1 0.6 1.8 1 1 0 1 1 1 0 GAF and HTH_10 associated domain Ribosomal_S4e PF00900.20 CRK15606.1 - 2.5e-35 120.2 0.1 6.2e-35 118.9 0.1 1.7 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 CRK15606.1 - 8.4e-24 83.0 0.1 1.5e-23 82.2 0.1 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 CRK15606.1 - 4e-17 62.0 4.0 8.9e-17 60.9 4.0 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain Myb_DNA-binding PF00249.31 CRK15606.1 - 2.4e-15 56.4 0.0 2e-07 31.1 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CRK15606.1 - 4e-07 30.2 0.0 0.008 16.4 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain S4 PF01479.25 CRK15606.1 - 5.8e-06 25.9 0.0 1.1e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 S4 domain SLIDE PF09111.10 CRK15606.1 - 7.7e-06 25.9 0.3 0.017 15.1 0.0 2.6 3 0 0 3 3 3 2 SLIDE KOW PF00467.29 CRK15606.1 - 0.00019 21.3 3.8 0.00022 21.0 1.9 2.2 2 0 0 2 2 2 1 KOW motif CHDCT2 PF08074.11 CRK15606.1 - 0.039 14.1 0.0 0.2 11.8 0.0 2.0 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain Septin PF00735.18 CRK15610.1 - 3.2e-18 66.0 0.0 2.2e-08 33.8 0.0 2.2 2 0 0 2 2 2 2 Septin AAA_23 PF13476.6 CRK15610.1 - 0.0029 18.1 0.1 0.0088 16.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 CRK15610.1 - 0.011 15.1 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_18 PF13238.6 CRK15610.1 - 0.014 15.9 0.1 0.45 11.1 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CRK15610.1 - 0.015 15.7 0.0 0.056 13.8 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain DUF3313 PF11769.8 CRK15610.1 - 0.028 14.2 0.1 0.11 12.3 0.0 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF3313) BUD22 PF09073.10 CRK15610.1 - 0.078 12.3 3.9 0.12 11.7 3.9 1.3 1 0 0 1 1 1 0 BUD22 Pox_A32 PF04665.12 CRK15610.1 - 0.17 11.3 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein ABC1 PF03109.16 CRK15612.1 - 2.2e-20 73.0 0.0 4.2e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 CRK15612.1 - 0.0011 19.0 0.0 0.0081 16.1 0.0 2.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family SUR7 PF06687.12 CRK15613.1 - 9.2e-25 87.5 11.8 1.4e-24 86.9 11.8 1.2 1 0 0 1 1 1 1 SUR7/PalI family SUR7 PF06687.12 CRK15615.1 - 2.8e-24 86.0 12.4 4.2e-24 85.4 12.4 1.2 1 0 0 1 1 1 1 SUR7/PalI family MARVEL PF01284.23 CRK15615.1 - 9.8 6.2 12.8 24 4.9 12.8 1.7 1 1 0 1 1 1 0 Membrane-associating domain Amidase PF01425.21 CRK15617.1 - 4e-100 335.9 0.0 7.2e-100 335.1 0.0 1.4 1 0 0 1 1 1 1 Amidase zf-MYND PF01753.18 CRK15617.1 - 0.0011 19.0 2.1 0.0052 16.9 2.1 2.2 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 CRK15617.1 - 0.13 12.6 0.8 0.33 11.3 0.8 1.7 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding VATC PF18716.1 CRK15617.1 - 0.32 10.9 2.0 1 9.3 2.0 1.8 1 0 0 1 1 1 0 Vms1-associating treble clef domain Aa_trans PF01490.18 CRK15618.1 - 6.3e-12 44.9 13.1 8e-12 44.6 13.1 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3149 PF11346.8 CRK15618.1 - 0.043 13.4 2.5 0.11 12.1 2.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) DUF2975 PF11188.8 CRK15618.1 - 8.6 6.2 17.2 0.63 9.9 0.4 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2975) zf-MYND PF01753.18 CRK15620.1 - 0.0084 16.2 4.3 0.0084 16.2 4.3 2.5 3 0 0 3 3 3 1 MYND finger zf-C6H2 PF15801.5 CRK15620.1 - 0.39 11.1 7.3 0.12 12.7 0.8 2.4 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding VATC PF18716.1 CRK15620.1 - 2.7 7.9 6.5 0.39 10.6 2.0 1.9 2 0 0 2 2 2 0 Vms1-associating treble clef domain Amidase PF01425.21 CRK15621.1 - 2.1e-105 353.3 0.0 2.9e-105 352.8 0.0 1.2 1 0 0 1 1 1 1 Amidase Aa_trans PF01490.18 CRK15622.1 - 1e-23 83.7 28.9 3e-19 69.0 17.5 2.1 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein DUF3149 PF11346.8 CRK15622.1 - 6.9 6.4 10.8 0.26 10.9 2.7 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3149) SF3b10 PF07189.11 CRK15624.1 - 2.9e-37 126.6 0.0 3.3e-37 126.5 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) MAGE PF01454.19 CRK15625.1 - 2.4e-56 190.8 0.0 3.4e-56 190.3 0.0 1.2 1 0 0 1 1 1 1 MAGE family RRN3 PF05327.11 CRK15625.1 - 2.1 6.8 7.5 3.2 6.2 7.5 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 RXT2_N PF08595.11 CRK15625.1 - 7.5 6.6 6.8 14 5.6 6.8 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal SLS PF14611.6 CRK15626.1 - 1.7e-26 93.4 2.0 3.8e-26 92.3 0.1 2.2 2 0 0 2 2 2 1 Mitochondrial inner-membrane-bound regulator Imm74 PF15603.6 CRK15626.1 - 0.067 13.4 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 Immunity protein 74 GTP_EFTU_D3 PF03143.17 CRK15627.1 - 2.2e-41 140.7 0.0 5.1e-41 139.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU PF00009.27 CRK15627.1 - 1.9e-25 89.5 0.0 3.1e-25 88.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 CRK15627.1 - 4.1e-15 55.9 1.7 6.1e-15 55.4 0.6 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 CRK15627.1 - 0.048 13.6 0.3 0.13 12.1 0.3 1.7 1 0 0 1 1 1 0 Elongation factor Tu domain 4 adh_short_C2 PF13561.6 CRK15628.1 - 2.1e-52 178.0 0.4 3.4e-52 177.3 0.4 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRK15628.1 - 5.6e-48 163.0 0.5 7.6e-48 162.6 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CRK15628.1 - 2e-09 37.6 0.2 2.9e-09 37.1 0.2 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 CRK15629.1 - 4.2e-31 108.0 0.0 6.8e-31 107.4 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein DUF2462 PF09495.10 CRK15629.1 - 2.8e-11 44.0 13.9 5.8e-11 43.0 13.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) PP-binding PF00550.25 CRK15629.1 - 7.4e-07 29.4 0.0 1.7e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Pyridoxal_deC PF00282.19 CRK15630.1 - 3.1e-14 52.5 0.0 4.7e-07 28.9 0.0 2.1 1 1 1 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain DUF92 PF01940.16 CRK15631.1 - 1.2e-83 280.2 0.7 1.5e-83 279.9 0.7 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 CTP_transf_1 PF01148.20 CRK15631.1 - 0.018 14.8 3.5 0.018 14.8 3.5 2.0 2 0 0 2 2 2 0 Cytidylyltransferase family Cu-oxidase_3 PF07732.15 CRK15633.1 - 2e-41 140.8 7.3 3.3e-40 136.8 1.1 2.9 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 CRK15633.1 - 1.5e-39 134.9 10.8 1.1e-35 122.3 1.7 3.7 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 CRK15633.1 - 4.7e-19 69.1 0.2 5.6e-17 62.3 0.0 2.9 2 1 1 3 3 3 1 Multicopper oxidase SAT PF16073.5 CRK15634.1 - 5.4e-76 255.5 1.4 5.4e-76 255.5 1.4 1.9 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis ketoacyl-synt PF00109.26 CRK15634.1 - 5.1e-74 249.0 0.0 1e-73 248.1 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 CRK15634.1 - 2.9e-45 155.1 0.0 6.5e-45 154.0 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 CRK15634.1 - 3.9e-36 123.7 0.4 8e-36 122.6 0.4 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.20 CRK15634.1 - 6.7e-23 82.0 0.0 3.7e-22 79.6 0.0 2.2 2 0 0 2 2 2 1 Thioesterase domain PP-binding PF00550.25 CRK15634.1 - 8.2e-21 74.1 4.5 4.8e-11 42.8 0.2 3.1 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.6 CRK15634.1 - 8.5e-18 64.6 0.0 1.6e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 CRK15634.1 - 0.00013 22.4 0.0 0.00034 21.1 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 CRK15634.1 - 0.00028 20.3 0.1 0.0023 17.4 0.0 2.3 2 0 0 2 2 2 1 Thiolase, N-terminal domain Abhydrolase_1 PF00561.20 CRK15634.1 - 0.0027 17.4 0.0 0.02 14.6 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CRK15634.1 - 0.006 17.2 6.2 0.24 12.0 0.1 3.1 3 0 0 3 3 3 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CRK15634.1 - 0.056 12.7 0.0 1.8 7.7 0.0 2.4 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF1996 PF09362.10 CRK15635.1 - 1.9e-42 145.9 0.1 2.3e-42 145.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Zn_clus PF00172.18 CRK15637.1 - 1.9e-07 31.1 8.4 3.1e-07 30.4 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RNA_pol_3_Rpc31 PF11705.8 CRK15637.1 - 0.14 12.3 0.6 0.23 11.7 0.2 1.4 1 1 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 zf-C2H2 PF00096.26 CRK15639.1 - 1.8e-07 31.2 13.4 0.00013 22.3 1.5 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type Zn_clus PF00172.18 CRK15639.1 - 6.2e-05 23.0 11.3 6.2e-05 23.0 11.3 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-H2C2_2 PF13465.6 CRK15639.1 - 0.001 19.4 11.9 0.0017 18.7 1.7 3.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 CRK15639.1 - 0.0021 18.7 12.2 0.04 14.8 1.2 3.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CRK15639.1 - 0.075 13.3 3.0 0.76 10.1 0.7 2.8 1 1 1 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CRK15639.1 - 0.51 10.8 3.0 29 5.3 0.2 3.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 CRK15639.1 - 0.61 10.0 4.1 0.24 11.4 0.2 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-BED PF02892.15 CRK15639.1 - 1.9 8.6 4.9 5.8 7.0 4.9 1.8 1 0 0 1 1 1 0 BED zinc finger DZR PF12773.7 CRK15639.1 - 7.4 6.7 15.1 0.079 13.0 1.4 2.6 2 0 0 2 2 2 0 Double zinc ribbon zf-C2H2_11 PF16622.5 CRK15639.1 - 8 6.3 7.0 32 4.4 0.1 2.8 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 CRK15639.1 - 8.5 6.8 7.5 23 5.4 5.2 2.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Glyco_transf_8 PF01501.20 CRK15640.1 - 1.5e-13 50.9 0.0 1.2e-12 48.0 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 8 Spc24 PF08286.11 CRK15643.1 - 6.3e-36 122.8 0.6 5.6e-34 116.5 0.0 2.2 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 Vps5 PF09325.10 CRK15643.1 - 0.04 13.5 3.2 0.053 13.0 3.2 1.2 1 0 0 1 1 1 0 Vps5 C terminal like Nsp1_C PF05064.13 CRK15643.1 - 0.11 12.4 2.1 2.1 8.2 0.2 2.3 2 1 0 2 2 2 0 Nsp1-like C-terminal region V_ATPase_I PF01496.19 CRK15643.1 - 0.12 10.3 1.5 0.13 10.2 1.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FAA_hydro_N_2 PF18288.1 CRK15643.1 - 0.37 11.2 3.0 1.1 9.7 0.9 2.6 2 1 1 3 3 3 0 Fumarylacetoacetase N-terminal domain 2 Abi_C PF14355.6 CRK15643.1 - 0.56 10.3 3.6 2.5 8.2 2.6 2.6 2 1 1 3 3 3 0 Abortive infection C-terminus DUF1690 PF07956.11 CRK15643.1 - 0.75 10.2 8.0 1.7 9.0 8.0 1.7 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) CLZ PF16526.5 CRK15643.1 - 0.81 10.1 6.7 1.7 9.0 0.9 2.7 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FUSC PF04632.12 CRK15643.1 - 1.1 7.7 9.5 1.3 7.5 9.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family APG6_N PF17675.1 CRK15643.1 - 1.2 9.7 11.9 2.6 8.6 11.8 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region SlyX PF04102.12 CRK15643.1 - 1.5 9.5 5.6 4.5 8.0 0.9 2.6 2 1 0 2 2 2 0 SlyX DUF4164 PF13747.6 CRK15643.1 - 3.4 8.0 17.3 0.6 10.4 9.1 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) XhlA PF10779.9 CRK15643.1 - 6.3 7.1 5.7 3.2 8.0 1.3 2.2 2 0 0 2 2 2 0 Haemolysin XhlA Fis1_TPR_C PF14853.6 CRK15644.1 - 6.4e-25 87.0 2.0 1.1e-24 86.2 2.0 1.4 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 CRK15644.1 - 1.2e-16 60.1 0.1 2.5e-16 59.1 0.1 1.6 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat zf-RING_2 PF13639.6 CRK15644.1 - 1.4e-13 50.9 7.5 1.4e-13 50.9 7.5 2.0 2 0 0 2 2 1 1 Ring finger domain zf-RING_11 PF17123.5 CRK15644.1 - 2.3e-10 40.0 2.6 2.3e-10 40.0 2.6 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 CRK15644.1 - 9e-10 38.2 7.4 9e-10 38.2 7.4 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CRK15644.1 - 2.1e-08 33.9 4.7 2.1e-08 33.9 4.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CRK15644.1 - 9.2e-08 32.3 6.2 2.3e-07 31.0 6.2 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 CRK15644.1 - 2.5e-06 27.3 4.7 2.5e-06 27.3 4.7 2.2 3 0 0 3 3 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CRK15644.1 - 1.3e-05 25.0 7.2 1.3e-05 25.0 7.2 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CRK15644.1 - 0.00016 21.5 4.6 0.00016 21.5 4.6 1.8 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 CRK15644.1 - 0.00085 19.3 2.0 0.0025 17.8 2.0 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 CRK15644.1 - 0.0025 17.8 6.4 0.0067 16.4 6.4 1.8 1 0 0 1 1 1 1 RING-type zinc-finger TPR_2 PF07719.17 CRK15644.1 - 0.046 13.9 2.2 0.086 13.0 2.2 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-RING_4 PF14570.6 CRK15644.1 - 0.16 11.8 4.9 0.32 10.8 4.9 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Baculo_RING PF05883.11 CRK15644.1 - 0.17 11.9 0.6 0.32 11.0 0.6 1.4 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain RINGv PF12906.7 CRK15644.1 - 0.26 11.4 8.8 0.53 10.5 8.8 1.5 1 0 0 1 1 1 0 RING-variant domain zf-P11 PF03854.14 CRK15644.1 - 1 9.0 5.6 0.46 10.2 1.7 2.2 2 0 0 2 2 2 0 P-11 zinc finger zf-C3HC4_4 PF15227.6 CRK15644.1 - 1.1 9.5 5.7 2.8 8.2 5.7 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3H2C3 PF17122.5 CRK15644.1 - 4.8 7.3 5.9 12 6.1 5.9 1.7 1 0 0 1 1 1 0 Zinc-finger Zn_ribbon_17 PF17120.5 CRK15644.1 - 7.3 6.3 11.9 0.23 11.1 5.2 2.0 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Fungal_trans PF04082.18 CRK15646.1 - 1.7e-14 53.5 0.0 4.9e-14 52.0 0.0 1.8 1 0 0 1 1 1 1 Fungal specific transcription factor domain Rrn6 PF10214.9 CRK15646.1 - 0.019 13.5 11.2 0.032 12.7 11.2 1.4 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor HNOBA PF07701.14 CRK15646.1 - 0.048 13.1 4.3 3.4 7.0 4.2 2.2 2 0 0 2 2 2 0 Heme NO binding associated SpoIIP PF07454.11 CRK15646.1 - 0.086 12.3 6.3 0.17 11.3 6.3 1.4 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Presenilin PF01080.17 CRK15646.1 - 0.23 10.2 8.0 0.43 9.3 8.0 1.4 1 0 0 1 1 1 0 Presenilin CPSF100_C PF13299.6 CRK15646.1 - 0.31 11.2 4.7 0.68 10.1 4.7 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal TFIIA PF03153.13 CRK15646.1 - 0.34 10.9 33.0 0.012 15.6 26.3 1.8 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CRK15646.1 - 0.42 10.2 34.4 0.79 9.3 34.4 1.4 1 0 0 1 1 1 0 Spt20 family eIF-3_zeta PF05091.12 CRK15646.1 - 0.44 9.5 11.8 0.69 8.8 11.8 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PAT1 PF09770.9 CRK15646.1 - 0.58 8.4 20.1 0.85 7.8 20.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ORC6 PF05460.13 CRK15646.1 - 0.63 9.3 10.9 1.1 8.4 10.9 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Neur_chan_memb PF02932.16 CRK15646.1 - 0.9 9.6 5.5 2 8.4 5.5 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region NARP1 PF12569.8 CRK15646.1 - 1 8.2 7.0 1.5 7.6 7.0 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Glyco_hydro_35 PF01301.19 CRK15646.1 - 1.1 8.8 5.0 2 8.0 5.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 PRIMA1 PF16101.5 CRK15646.1 - 1.7 8.7 6.5 1.4 9.0 3.9 2.3 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Suf PF05843.14 CRK15646.1 - 1.9 8.4 17.7 1.4 8.8 14.8 2.0 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) EPL1 PF10513.9 CRK15646.1 - 2.7 8.4 10.9 0.34 11.3 6.7 1.6 2 0 0 2 2 1 0 Enhancer of polycomb-like Endostatin PF06482.11 CRK15646.1 - 2.8 7.3 11.4 4.8 6.6 11.4 1.3 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin DUF4770 PF15994.5 CRK15646.1 - 2.8 8.2 12.9 5.8 7.1 12.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Connexin PF00029.19 CRK15646.1 - 3.4 7.4 6.0 7.4 6.3 6.0 1.5 1 0 0 1 1 1 0 Connexin Band_3_cyto PF07565.13 CRK15646.1 - 4.2 7.1 7.1 7.4 6.3 7.1 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF2397 PF09660.10 CRK15646.1 - 4.6 6.0 11.6 8.5 5.2 11.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) DUF4175 PF13779.6 CRK15646.1 - 4.9 4.9 25.8 7.6 4.3 25.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) API5 PF05918.11 CRK15646.1 - 5.5 5.7 10.1 9 5.0 10.1 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DUF3408 PF11888.8 CRK15646.1 - 6.7 6.8 12.6 18 5.4 12.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) EMC3_TMCO1 PF01956.16 CRK15646.1 - 6.8 6.4 7.1 12 5.6 7.1 1.3 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Fungal_trans PF04082.18 CRK15647.1 - 6.5e-31 107.3 0.0 1.8e-30 105.8 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK15647.1 - 6.1e-09 35.9 7.6 1e-08 35.2 7.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SH3_9 PF14604.6 CRK15650.1 - 3.1e-10 39.7 0.0 5.4e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CRK15650.1 - 1.6e-06 27.6 0.0 2.8e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CRK15650.1 - 0.00013 21.6 0.0 0.00023 20.8 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain DUF4448 PF14610.6 CRK15650.1 - 0.028 14.2 0.0 0.046 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF5305 PF17231.2 CRK15650.1 - 0.18 11.2 0.0 0.31 10.4 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Gar1 PF04410.14 CRK15651.1 - 9.3e-47 158.7 0.5 1.6e-46 157.9 0.5 1.3 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region DUF4266 PF14086.6 CRK15651.1 - 0.023 15.7 6.0 0.11 13.5 6.0 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4266) Zn_clus PF00172.18 CRK15652.1 - 2.5e-06 27.5 2.9 4.3e-06 26.7 2.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 CRK15652.1 - 4.3e-05 22.5 0.6 0.00068 18.5 0.1 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Pkinase PF00069.25 CRK15652.1 - 0.00091 18.7 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain DEAD PF00270.29 CRK15653.1 - 2.1e-35 122.1 0.3 1.8e-18 67.0 0.2 2.5 1 1 1 2 2 2 2 DEAD/DEAH box helicase DUF4217 PF13959.6 CRK15653.1 - 2.4e-21 75.7 0.0 8.4e-21 74.0 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.31 CRK15653.1 - 5.8e-21 74.9 0.0 3.8e-20 72.3 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.6 CRK15653.1 - 0.0085 16.3 0.0 0.024 14.8 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain RXLR PF16810.5 CRK15653.1 - 0.39 11.1 5.3 0.072 13.5 1.2 1.8 2 0 0 2 2 2 0 RXLR phytopathogen effector protein, Avirulence activity Sad1_UNC PF07738.13 CRK15654.1 - 2.3e-06 27.7 0.0 0.00053 20.0 0.0 3.1 2 1 0 2 2 2 1 Sad1 / UNC-like C-terminal PAPS_reduct PF01507.19 CRK15655.1 - 2.7e-06 27.5 0.0 3.4e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Sad1_UNC PF07738.13 CRK15656.1 - 3e-05 24.1 0.0 0.00057 19.9 0.0 2.5 2 1 0 2 2 2 1 Sad1 / UNC-like C-terminal Epimerase PF01370.21 CRK15657.1 - 8.7e-49 166.1 0.0 1.1e-48 165.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CRK15657.1 - 1.3e-46 159.6 0.0 2.3e-46 158.7 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 CRK15657.1 - 2.4e-20 72.7 0.0 1.3e-17 63.7 0.0 2.0 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 CRK15657.1 - 6e-14 51.9 0.0 6.1e-12 45.3 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 CRK15657.1 - 3.9e-12 45.9 0.0 5.4e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 CRK15657.1 - 1.1e-08 35.3 0.0 1.9e-08 34.4 0.0 1.4 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 CRK15657.1 - 4.2e-08 32.9 0.0 6.4e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 CRK15657.1 - 3.6e-07 29.6 0.0 5e-06 25.9 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 CRK15657.1 - 1.4e-06 28.4 0.0 2e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 CRK15657.1 - 0.001 19.3 0.0 0.0019 18.5 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain adh_short_C2 PF13561.6 CRK15657.1 - 0.0014 18.3 0.0 0.0027 17.3 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.13 CRK15657.1 - 0.0055 16.3 0.0 0.078 12.5 0.0 2.2 2 0 0 2 2 2 1 NmrA-like family UDPG_MGDP_dh_N PF03721.14 CRK15657.1 - 0.012 15.2 0.1 0.027 14.1 0.1 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ADH_zinc_N PF00107.26 CRK15658.1 - 1.7e-25 89.5 2.0 2.8e-25 88.8 2.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CRK15658.1 - 3.1e-18 67.1 0.1 6.8e-18 66.0 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CRK15658.1 - 2.9e-06 27.1 0.0 8.2e-06 25.7 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 CRK15658.1 - 2.2e-05 24.3 0.0 4.5e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase adh_short PF00106.25 CRK15658.1 - 0.01 15.3 1.4 0.021 14.3 1.4 1.5 1 0 0 1 1 1 0 short chain dehydrogenase Epimerase PF01370.21 CRK15659.1 - 1.2e-54 185.3 0.0 2.4e-48 164.7 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CRK15659.1 - 3.7e-52 177.8 0.0 6.3e-45 154.0 0.0 3.0 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 CRK15659.1 - 4.5e-20 71.8 0.0 4.7e-17 61.9 0.0 3.1 3 0 0 3 3 3 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 CRK15659.1 - 3.8e-13 49.2 0.0 2.5e-11 43.3 0.0 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 CRK15659.1 - 1.2e-11 44.3 0.0 2e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 CRK15659.1 - 3.1e-08 33.7 0.0 6.7e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 CRK15659.1 - 1.2e-07 31.4 0.0 2.1e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 CRK15659.1 - 1.9e-06 27.2 0.0 1.8e-05 24.0 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 CRK15659.1 - 3.3e-06 27.1 0.0 7.3e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H-binding Ank_2 PF12796.7 CRK15659.1 - 5.9e-05 23.6 0.0 0.00015 22.3 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) adh_short_C2 PF13561.6 CRK15659.1 - 0.0041 16.7 0.0 0.008 15.8 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.13 CRK15659.1 - 0.0062 16.1 0.0 0.24 10.9 0.0 2.9 3 0 0 3 3 3 1 NmrA-like family Ank_3 PF13606.6 CRK15659.1 - 0.0066 16.9 0.1 5.1 8.0 0.0 4.0 3 0 0 3 3 3 1 Ankyrin repeat UDPG_MGDP_dh_N PF03721.14 CRK15659.1 - 0.027 14.1 0.1 0.062 12.9 0.1 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Rib_hydrolayse PF02267.17 CRK15659.1 - 0.038 13.4 0.0 9.7 5.5 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosyl cyclase G-gamma PF00631.22 CRK15659.1 - 0.072 13.1 0.0 21 5.2 0.0 2.4 2 0 0 2 2 2 0 GGL domain UDP-g_GGTase PF06427.11 CRK15659.1 - 0.1 12.7 0.0 28 4.9 0.0 2.6 2 0 0 2 2 2 0 UDP-glucose:Glycoprotein Glucosyltransferase ADH_zinc_N PF00107.26 CRK15660.1 - 1.8e-25 89.4 1.7 3e-25 88.7 1.7 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CRK15660.1 - 2.9e-18 67.2 0.0 5.9e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CRK15660.1 - 3.8e-06 26.7 0.0 1e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 CRK15660.1 - 6e-05 22.9 0.0 0.00012 21.9 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase adh_short PF00106.25 CRK15660.1 - 0.021 14.3 2.7 0.044 13.3 2.7 1.5 1 1 0 1 1 1 0 short chain dehydrogenase Ank_2 PF12796.7 CRK15661.1 - 9.9e-61 202.3 28.2 4.3e-05 24.0 0.0 26.4 20 7 4 27 27 27 13 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CRK15661.1 - 9.6e-22 77.1 25.4 0.037 14.6 0.0 22.5 25 4 2 27 27 27 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 CRK15661.1 - 4.8e-20 71.4 27.3 8.6e-07 29.1 0.0 16.8 20 3 3 23 23 23 3 Ankyrin repeats (many copies) Ank PF00023.30 CRK15661.1 - 1.6e-18 66.2 42.5 0.033 14.6 0.1 21.6 23 1 0 23 23 23 4 Ankyrin repeat Ank_3 PF13606.6 CRK15661.1 - 1.3e-16 59.0 36.4 0.18 12.4 0.0 28.1 39 0 0 39 39 39 2 Ankyrin repeat DUF1722 PF08349.11 CRK15661.1 - 5e-06 26.8 2.0 0.13 12.6 0.1 2.9 2 0 0 2 2 2 2 Protein of unknown function (DUF1722) Arg_repressor PF01316.21 CRK15661.1 - 0.0054 16.5 0.0 8.4 6.2 0.0 3.3 2 0 0 2 2 2 2 Arginine repressor, DNA binding domain EntA_Immun PF08951.10 CRK15661.1 - 0.057 13.8 3.1 11 6.4 0.2 3.3 2 0 0 2 2 2 0 Enterocin A Immunity NACHT_sigma PF17106.5 CRK15662.1 - 0.064 13.4 14.9 0.84 9.8 0.8 3.4 3 0 0 3 3 3 0 Sigma domain on NACHT-NTPases Gamma-thionin PF00304.20 CRK15662.1 - 0.22 11.8 16.8 0.16 12.2 5.2 2.3 2 0 0 2 2 2 0 Gamma-thionin family Toxin_11 PF07473.11 CRK15662.1 - 0.35 11.0 12.9 0.31 11.1 1.7 2.5 2 0 0 2 2 2 0 Spasmodic peptide gm9a; conotoxin from Conus species Colipase-like PF15083.6 CRK15662.1 - 0.98 9.6 4.6 3.5 7.8 0.2 2.2 2 0 0 2 2 2 0 Colipase-like Colipase PF01114.18 CRK15662.1 - 5.8 6.7 17.5 0.63 9.8 5.5 2.4 2 0 0 2 2 2 0 Colipase, N-terminal domain Glyco_hydro_106 PF17132.4 CRK15663.1 - 1.4e-33 116.2 0.1 2.7e-25 88.8 0.0 2.1 1 1 0 2 2 2 2 alpha-L-rhamnosidase CLP1_N PF16573.5 CRK15663.1 - 3.9e-09 36.6 0.0 7.8e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Glyco_hydro_2_N PF02837.18 CRK15663.1 - 3.9e-06 26.9 0.0 7.8e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Pmp3 PF01679.17 CRK15664.1 - 9e-19 67.4 8.9 1.4e-18 66.8 8.9 1.3 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Ank_2 PF12796.7 CRK15664.1 - 0.008 16.7 0.0 0.016 15.8 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CRK15664.1 - 0.05 14.2 0.0 12 6.9 0.0 2.8 2 0 0 2 2 2 0 Ankyrin repeat Arb1 PF09692.10 CRK15665.1 - 2.5e-123 412.2 0.0 2.9e-123 412.0 0.0 1.0 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 Gamma-thionin PF00304.20 CRK15666.1 - 0.25 11.6 17.3 0.16 12.2 5.5 2.4 2 0 0 2 2 2 0 Gamma-thionin family Toxin_11 PF07473.11 CRK15666.1 - 0.65 10.1 13.8 0.36 11.0 1.9 2.5 2 0 0 2 2 2 0 Spasmodic peptide gm9a; conotoxin from Conus species Colipase PF01114.18 CRK15666.1 - 1 9.1 15.0 0.15 11.7 3.6 2.3 2 0 0 2 2 2 0 Colipase, N-terminal domain Colipase-like PF15083.6 CRK15666.1 - 1.2 9.3 4.8 3.2 8.0 0.2 2.1 2 0 0 2 2 2 0 Colipase-like NACHT_sigma PF17106.5 CRK15666.1 - 2.3 8.4 19.9 0.84 9.8 0.8 3.4 3 0 0 3 3 3 0 Sigma domain on NACHT-NTPases CLP1_P PF16575.5 CRK15667.1 - 2.5e-36 125.3 0.0 4.7e-36 124.3 0.0 1.5 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 CRK15667.1 - 6.2e-27 93.6 0.0 1.1e-26 92.9 0.0 1.4 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.14 CRK15667.1 - 2e-26 92.7 0.0 1.2e-25 90.2 0.0 2.3 2 1 0 2 2 2 1 Pre-mRNA cleavage complex II protein Clp1 KTI12 PF08433.10 CRK15667.1 - 0.0002 20.9 0.0 0.081 12.4 0.0 2.2 2 0 0 2 2 2 2 Chromatin associated protein KTI12 AAA_24 PF13479.6 CRK15667.1 - 0.0032 17.2 0.0 0.0062 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 CRK15667.1 - 0.0084 16.2 0.1 0.041 13.9 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.6 CRK15667.1 - 0.0087 16.6 0.0 0.042 14.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.17 CRK15667.1 - 0.011 15.6 0.1 0.025 14.4 0.0 1.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA PF00004.29 CRK15667.1 - 0.023 15.1 0.1 0.08 13.4 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 CRK15667.1 - 0.025 14.7 0.0 0.074 13.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CRK15667.1 - 0.039 14.3 0.0 0.068 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 CRK15667.1 - 0.051 13.9 0.0 0.094 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_35 PF14516.6 CRK15667.1 - 0.13 11.1 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_19 PF13245.6 CRK15667.1 - 0.18 12.1 0.0 0.44 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 CRK15667.1 - 0.19 11.1 0.0 0.46 9.9 0.0 1.5 2 0 0 2 2 2 0 Bacterial TniB protein Pmp3 PF01679.17 CRK15668.1 - 5.7e-19 68.1 8.9 7.4e-19 67.7 8.9 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Arb1 PF09692.10 CRK15669.1 - 3.5e-122 408.4 0.0 4.2e-122 408.2 0.0 1.0 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 IPK PF03770.16 CRK15670.1 - 1.3e-90 302.5 0.0 1.8e-50 171.6 0.0 2.4 2 0 0 2 2 2 2 Inositol polyphosphate kinase HA2 PF04408.23 CRK15670.1 - 1.4e-22 80.0 0.1 3.9e-22 78.6 0.1 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CRK15670.1 - 8e-13 48.7 0.0 1.9e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 CRK15670.1 - 1.5e-09 38.1 0.0 3.5e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 CRK15670.1 - 1.3e-06 28.8 0.0 3e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 CRK15670.1 - 5.2e-05 23.1 0.4 0.00025 20.9 0.4 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 CRK15670.1 - 0.0003 20.6 0.1 0.00061 19.6 0.1 1.5 1 0 0 1 1 1 1 AAA domain CdiI PF07262.11 CRK15670.1 - 0.0026 17.5 0.0 5.5 6.7 0.0 3.8 4 0 0 4 4 4 1 CDI immunity protein AAA_19 PF13245.6 CRK15670.1 - 0.0056 17.0 0.1 0.014 15.7 0.1 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 CRK15670.1 - 0.007 15.5 0.0 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein PhoH PF02562.16 CRK15670.1 - 0.083 12.3 0.0 0.21 11.0 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein OB_NTP_bind PF07717.16 CRK15671.1 - 2.7e-23 82.1 0.0 5.5e-23 81.1 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 CRK15671.1 - 3.2e-22 78.9 0.0 3.2e-22 78.9 0.0 3.1 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CRK15671.1 - 5.1e-13 49.3 0.0 1.6e-12 47.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 CRK15671.1 - 6.9e-12 45.5 0.3 1.4e-11 44.6 0.3 1.5 1 0 0 1 1 1 1 S1 RNA binding domain AAA_22 PF13401.6 CRK15671.1 - 1e-06 29.1 0.0 2.5e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 CRK15671.1 - 6e-05 22.9 0.5 0.00023 21.0 0.5 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 CRK15671.1 - 0.00021 21.1 0.1 0.00051 19.8 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CRK15671.1 - 0.0053 17.1 0.1 0.012 16.0 0.1 1.5 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 CRK15671.1 - 0.0058 15.7 0.0 0.013 14.6 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein PhoH PF02562.16 CRK15671.1 - 0.072 12.5 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein ABC_tran PF00005.27 CRK15671.1 - 0.15 12.6 0.2 2.2 8.8 0.1 2.7 1 1 0 2 2 2 0 ABC transporter AAA_14 PF13173.6 CRK15671.1 - 0.2 11.7 0.2 1.7 8.7 0.2 2.2 1 1 0 1 1 1 0 AAA domain Hydrolase_6 PF13344.6 CRK15672.1 - 1.2e-25 89.5 0.0 3.1e-25 88.2 0.0 1.7 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CRK15672.1 - 2.9e-15 56.1 0.0 4.8e-14 52.2 0.0 2.5 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 CRK15672.1 - 9.6e-06 26.0 0.1 0.27 11.5 0.0 3.7 2 1 2 4 4 4 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CRK15672.1 - 0.024 14.7 0.1 8.5 6.4 0.0 2.8 3 1 1 4 4 4 0 Haloacid dehalogenase-like hydrolase HAD PF12710.7 CRK15672.1 - 0.15 12.5 0.2 29 5.0 0.1 3.4 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Glyco_hydro_16 PF00722.21 CRK15673.1 - 0.00015 21.3 0.0 0.0006 19.3 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 MFS_1 PF07690.16 CRK15674.1 - 1.1e-13 50.9 22.2 1.6e-13 50.3 22.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3687 PF12459.8 CRK15674.1 - 2 8.0 5.6 0.62 9.6 0.7 2.4 2 0 0 2 2 2 0 D-Ala-teichoic acid biosynthesis protein TauD PF02668.16 CRK15677.1 - 1.9e-45 155.7 0.0 2.7e-45 155.3 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Ax_dynein_light PF10211.9 CRK15677.1 - 0.015 15.2 0.0 0.031 14.2 0.0 1.4 1 0 0 1 1 1 0 Axonemal dynein light chain UL16 PF17622.2 CRK15677.1 - 0.14 11.8 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 Viral unique long protein 16 Peptidase_M28 PF04389.17 CRK15678.1 - 1.7e-40 138.9 0.0 2.5e-40 138.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 CRK15678.1 - 4.5e-09 36.2 0.7 3.6e-08 33.3 0.1 2.4 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.28 CRK15678.1 - 2e-06 27.7 0.0 3.2e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 ADH_N PF08240.12 CRK15679.1 - 0.0031 17.4 0.2 0.0053 16.6 0.2 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Abhydrolase_3 PF07859.13 CRK15680.1 - 6.1e-16 58.9 0.1 1.2e-12 48.1 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CRK15680.1 - 3.5e-10 39.7 0.0 0.00017 21.1 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 CRK15680.1 - 0.00095 19.8 2.4 0.0013 19.4 2.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 CRK15680.1 - 0.003 17.1 0.0 0.88 9.1 0.0 2.3 2 0 0 2 2 2 2 Dienelactone hydrolase family Fungal_trans PF04082.18 CRK15681.1 - 1.2e-13 50.7 1.1 3e-13 49.4 1.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.6 CRK15681.1 - 5.3e-08 33.0 12.9 0.0015 19.2 2.4 3.5 2 0 0 2 2 2 2 C2H2-type zinc finger Zn_clus PF00172.18 CRK15681.1 - 5.1e-06 26.5 14.6 5.1e-06 26.5 14.6 1.7 2 0 0 2 2 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 CRK15681.1 - 6.3e-06 26.4 22.8 0.00026 21.3 3.7 3.2 3 0 0 3 3 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 CRK15681.1 - 0.0001 22.5 3.3 0.12 12.7 0.1 3.0 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CRK15681.1 - 0.00048 20.4 9.6 0.024 15.0 0.2 3.2 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 CRK15681.1 - 0.00057 20.2 4.7 0.00057 20.2 4.7 3.9 4 1 0 4 4 3 1 Zinc-finger double domain PS_pyruv_trans PF04230.13 CRK15681.1 - 0.0077 16.2 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide pyruvyl transferase Zn-C2H2_12 PF18112.1 CRK15681.1 - 0.037 14.5 1.4 0.1 13.1 0.1 2.5 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain Tfb2 PF03849.14 CRK15681.1 - 0.092 11.7 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcription factor Tfb2 zf-MYST PF17772.1 CRK15681.1 - 0.17 11.5 1.2 0.83 9.3 0.1 2.5 3 0 0 3 3 3 0 MYST family zinc finger domain zf-C2HC_2 PF13913.6 CRK15681.1 - 0.19 11.7 9.9 1.1 9.2 0.9 2.8 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-BED PF02892.15 CRK15681.1 - 3.3 7.8 6.6 46 4.1 1.9 2.6 1 1 1 2 2 2 0 BED zinc finger HIG_1_N PF04588.13 CRK15683.1 - 5.9e-05 23.2 5.7 5.9e-05 23.2 5.7 2.1 3 0 0 3 3 3 1 Hypoxia induced protein conserved region Romo1 PF10247.9 CRK15683.1 - 0.44 11.0 4.8 0.32 11.4 2.7 1.8 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 Aa_trans PF01490.18 CRK15684.1 - 1e-72 245.1 32.3 1.3e-72 244.8 32.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF4131 PF13567.6 CRK15684.1 - 5 6.7 10.6 0.79 9.3 1.1 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) Transketolase_N PF00456.21 CRK15687.1 - 7.9e-63 212.4 0.2 1.2e-62 211.8 0.2 1.3 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 CRK15687.1 - 3.3e-45 153.9 0.0 5.1e-45 153.3 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain ThiP_synth PF10120.9 CRK15687.1 - 0.15 11.7 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Thiamine-phosphate synthase TPR_2 PF07719.17 CRK15692.1 - 1.3e-10 40.6 0.1 0.0065 16.5 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 CRK15692.1 - 1e-09 38.5 2.1 0.005 17.1 0.0 4.1 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 CRK15692.1 - 1.5e-09 37.3 0.5 0.014 15.2 0.0 4.7 5 0 0 5 5 5 3 Tetratricopeptide repeat UCH PF00443.29 CRK15692.1 - 1.6e-09 37.6 0.0 2.2e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase TPR_8 PF13181.6 CRK15692.1 - 1.1e-07 31.5 0.1 4.5 7.7 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 CRK15692.1 - 7.8e-05 23.2 2.3 4.7 8.3 0.0 4.2 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 CRK15692.1 - 0.00041 20.8 0.1 0.031 14.8 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 CRK15692.1 - 0.0067 16.3 5.0 0.15 12.0 0.0 4.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 CRK15692.1 - 0.039 14.0 0.0 31 4.9 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 CRK15692.1 - 0.046 13.4 0.1 1.5 8.6 0.0 2.9 2 1 1 3 3 3 0 TPR repeat TPR_16 PF13432.6 CRK15692.1 - 0.24 12.1 6.3 0.75 10.5 0.0 3.9 4 1 1 5 5 3 0 Tetratricopeptide repeat SNF2_N PF00176.23 CRK15707.1 - 1.5e-37 129.2 0.1 2.1e-37 128.7 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 CRK15707.1 - 1.2e-19 70.0 1.2 1.9e-16 59.7 0.9 2.7 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 CRK15707.1 - 8e-08 32.5 0.0 1.3e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CRK15707.1 - 0.0017 18.6 0.0 0.0038 17.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain SWI2_SNF2 PF18766.1 CRK15707.1 - 0.01 15.6 0.0 0.043 13.5 0.0 1.9 2 0 0 2 2 2 1 SWI2/SNF2 ATPase DUF2075 PF09848.9 CRK15707.1 - 0.053 12.8 0.0 0.084 12.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ECD PF18432.1 CRK15707.1 - 0.13 12.2 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Extracellular Cadherin domain Sec7_N PF12783.7 CRK15721.1 - 1.4e-19 70.5 0.3 1.7e-19 70.3 0.3 1.1 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Biotin_lipoyl PF00364.22 CRK15722.1 - 4e-16 58.6 0.7 4.3e-16 58.5 0.7 1.0 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 CRK15722.1 - 0.063 13.1 0.0 0.075 12.9 0.0 1.2 1 0 0 1 1 1 0 Biotin-lipoyl like Ge1_WD40 PF16529.5 CRK15724.1 - 0.0021 17.1 0.0 0.018 14.1 0.0 2.0 1 1 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CRK15724.1 - 0.0083 14.8 0.0 0.28 9.8 0.0 2.0 2 0 0 2 2 2 2 Nucleoporin Nup120/160 YtfJ_HI0045 PF09695.10 CRK15724.1 - 0.16 11.6 0.1 0.5 10.0 0.1 1.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (YtfJ_HI0045) APH PF01636.23 CRK15725.1 - 9.7e-14 51.9 0.1 2.1e-13 50.8 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 CRK15725.1 - 0.0083 15.4 0.0 0.018 14.3 0.0 1.5 1 0 0 1 1 1 1 Fructosamine kinase Pkinase PF00069.25 CRK15725.1 - 0.055 12.8 0.0 17 4.6 0.0 2.9 3 0 0 3 3 3 0 Protein kinase domain HARE-HTH PF05066.13 CRK15725.1 - 0.058 13.8 0.1 0.14 12.6 0.1 1.6 1 0 0 1 1 1 0 HB1, ASXL, restriction endonuclease HTH domain Choline_kinase PF01633.20 CRK15725.1 - 0.061 12.9 0.0 3.7 7.1 0.0 2.5 2 0 0 2 2 2 0 Choline/ethanolamine kinase NINJA_B PF16136.5 CRK15726.1 - 1 9.7 17.9 1.5 9.2 17.9 1.2 1 0 0 1 1 1 0 Putative nuclear localisation signal NAP PF00956.18 CRK15728.1 - 1.1e-06 28.0 0.6 0.0018 17.5 0.0 2.9 1 1 2 3 3 3 3 Nucleosome assembly protein (NAP) WD40 PF00400.32 CRK15729.1 - 2.1e-28 98.0 5.4 2.1e-06 28.3 0.0 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK15729.1 - 2.2e-14 53.5 0.0 0.00027 21.2 0.0 4.8 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CRK15729.1 - 1.8e-06 28.0 0.4 0.01 15.7 0.1 3.1 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CRK15729.1 - 0.00012 21.2 0.3 0.67 8.9 0.0 3.0 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CRK15729.1 - 0.00012 20.9 0.1 0.49 9.0 0.0 2.7 1 1 2 3 3 3 2 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 CRK15729.1 - 0.022 13.7 0.0 0.56 9.1 0.0 2.1 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain WD40_like PF17005.5 CRK15729.1 - 0.022 14.1 0.0 0.062 12.6 0.0 1.6 1 1 1 2 2 2 0 WD40-like domain Nucleoporin_N PF08801.11 CRK15729.1 - 0.023 13.5 0.0 22 3.6 0.0 3.4 1 1 2 4 4 4 0 Nup133 N terminal like EF-hand_1 PF00036.32 CRK15731.1 - 2.9e-21 73.4 3.9 4.4e-06 25.8 0.3 3.1 3 0 0 3 3 3 3 EF hand EF-hand_5 PF13202.6 CRK15731.1 - 9.6e-20 69.1 5.2 3.5e-06 26.3 0.0 3.2 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 CRK15731.1 - 1.2e-19 70.5 1.2 1.7e-12 47.6 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CRK15731.1 - 1.5e-17 62.0 4.5 7.6e-06 25.4 0.1 3.1 2 1 1 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 CRK15731.1 - 1e-11 44.5 4.3 0.00096 19.0 0.1 3.1 1 1 2 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CRK15731.1 - 1.5e-07 31.7 0.0 2.7e-05 24.5 0.0 2.0 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 CRK15731.1 - 0.0016 18.3 0.1 2.4 8.1 0.0 2.3 2 0 0 2 2 2 2 EF hand EF-hand_4 PF12763.7 CRK15731.1 - 0.0042 17.0 0.7 1.9 8.5 0.0 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand DUF5580 PF17743.1 CRK15731.1 - 0.17 10.4 0.0 0.2 10.1 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5580) Peptidase_M43 PF05572.13 CRK15733.1 - 8.6e-08 32.2 0.0 2.2e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 CRK15733.1 - 0.019 15.1 0.1 0.099 12.8 0.1 2.1 1 1 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_M10 PF00413.24 CRK15733.1 - 0.019 14.8 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 Matrixin DAO PF01266.24 CRK15734.1 - 4.5e-22 79.1 1.4 4.5e-22 79.1 1.4 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CRK15734.1 - 0.00011 22.4 0.4 0.00011 22.4 0.4 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 CRK15734.1 - 0.0011 17.9 0.2 0.0015 17.4 0.2 1.1 1 0 0 1 1 1 1 Tryptophan halogenase Thi4 PF01946.17 CRK15734.1 - 0.0052 16.1 0.0 0.01 15.1 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Sacchrp_dh_NADP PF03435.18 CRK15734.1 - 0.066 13.5 1.6 0.2 11.9 0.1 2.4 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain MCRA PF06100.11 CRK15734.1 - 0.13 11.0 0.2 0.18 10.6 0.2 1.1 1 0 0 1 1 1 0 MCRA family Nop16 PF09420.10 CRK15735.1 - 1.1e-33 117.1 3.7 1.2e-33 117.0 3.7 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 ABC_tran_Xtn PF12848.7 CRK15735.1 - 0.022 14.8 6.5 0.032 14.3 6.5 1.3 1 0 0 1 1 1 0 ABC transporter HTH_38 PF13936.6 CRK15735.1 - 0.069 12.9 0.3 3 7.7 0.0 2.3 1 1 1 2 2 2 0 Helix-turn-helix domain MARVEL PF01284.23 CRK15736.1 - 0.00029 20.9 8.4 0.00062 19.8 8.3 1.6 1 1 1 2 2 2 1 Membrane-associating domain DUF4281 PF14108.6 CRK15736.1 - 0.00034 21.0 0.3 0.00062 20.1 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4281) Rit1_C PF17184.4 CRK15737.1 - 9.3e-78 261.4 0.0 2.8e-64 217.2 0.0 2.4 1 1 1 2 2 2 2 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 CRK15737.1 - 2.7e-35 121.0 0.0 6.1e-35 119.8 0.0 1.6 1 0 0 1 1 1 1 Rit1 DUSP-like domain HAD_2 PF13419.6 CRK15738.1 - 6.8e-22 78.4 0.0 8.8e-22 78.0 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CRK15738.1 - 1.3e-08 35.4 0.1 2.8e-08 34.3 0.1 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase NIF PF03031.18 CRK15738.1 - 1.1e-05 25.2 0.0 0.00021 21.1 0.0 2.1 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase Hydrolase_like PF13242.6 CRK15738.1 - 0.00013 22.0 0.0 0.00023 21.1 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 CRK15738.1 - 0.0018 18.7 0.0 0.0023 18.3 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UDPG_MGDP_dh_C PF03720.15 CRK15738.1 - 0.084 13.3 0.0 0.47 10.9 0.0 2.1 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain DnaJ_C PF01556.18 CRK15739.1 - 1.5e-37 129.0 0.5 2e-37 128.6 0.5 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CRK15739.1 - 8.9e-27 93.0 1.4 1.5e-26 92.3 1.4 1.4 1 0 0 1 1 1 1 DnaJ domain DUF2564 PF10819.8 CRK15740.1 - 0.0055 17.1 0.3 8.2 6.9 0.0 3.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2564) DUF2282 PF10048.9 CRK15740.1 - 0.011 15.7 0.0 11 6.2 0.0 2.9 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2282) SesA PF17107.5 CRK15740.1 - 0.011 15.9 0.6 7.3 6.8 0.1 2.7 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases FAM150 PF15129.6 CRK15740.1 - 0.017 15.3 0.1 11 6.2 0.0 2.6 2 0 0 2 2 2 0 FAM150 family Herpes_UL14 PF03580.14 CRK15740.1 - 0.032 14.5 2.1 6.6 7.0 0.1 2.8 2 0 0 2 2 2 0 Herpesvirus UL14-like protein SPAM PF02090.15 CRK15740.1 - 0.037 13.8 2.9 5.9 6.7 0.2 2.7 2 0 0 2 2 2 0 Salmonella surface presentation of antigen gene type M protein DUF4849 PF16141.5 CRK15740.1 - 0.09 12.0 0.0 16 4.7 0.0 2.4 2 0 0 2 2 2 0 Putative glycoside hydrolase Family 18, chitinase_18 DUF3018 PF11455.8 CRK15740.1 - 0.1 12.5 0.0 21 5.1 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3018) DUF4200 PF13863.6 CRK15740.1 - 1.4 9.4 14.8 1.5 9.2 0.9 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4200) Phage_term_smal PF05944.12 CRK15740.1 - 1.5 8.8 4.3 40 4.2 0.1 3.5 4 0 0 4 4 4 0 Phage small terminase subunit MerR-DNA-bind PF09278.11 CRK15740.1 - 3.2 8.3 4.9 46 4.7 0.4 3.1 2 0 0 2 2 2 0 MerR, DNA binding Cut12 PF11500.8 CRK15741.1 - 5e-47 159.5 14.8 5e-47 159.5 14.8 3.3 2 1 0 2 2 2 1 Spindle pole body formation-associated protein Fez1 PF06818.15 CRK15741.1 - 0.11 12.9 46.6 0.67 10.4 7.7 3.3 1 1 2 3 3 3 0 Fez1 DUF1843 PF08898.10 CRK15741.1 - 0.2 12.2 6.3 0.081 13.4 0.9 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) ATG16 PF08614.11 CRK15741.1 - 9.1 6.5 49.7 0.77 10.0 30.8 3.1 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) IGPD PF00475.18 CRK15742.1 - 4.4e-60 202.2 0.3 6.2e-60 201.7 0.3 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase DER1 PF04511.15 CRK15743.1 - 5.5e-22 78.6 6.0 6.5e-22 78.4 6.0 1.0 1 0 0 1 1 1 1 Der1-like family Jiraiya PF15038.6 CRK15743.1 - 0.12 11.7 2.9 0.68 9.3 0.0 2.4 2 1 0 2 2 2 0 Jiraiya DUF2070 PF09843.9 CRK15743.1 - 0.98 7.6 5.4 1.1 7.4 5.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) TruB_N PF01509.18 CRK15746.1 - 1.7e-22 80.4 0.2 8.7e-20 71.6 0.2 3.4 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.20 CRK15746.1 - 7.5e-22 77.1 1.1 1.4e-21 76.2 1.1 1.5 1 0 0 1 1 1 1 PUA domain TruB_C_2 PF16198.5 CRK15746.1 - 1e-21 76.8 0.9 2.4e-21 75.7 0.9 1.7 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain DKCLD PF08068.12 CRK15746.1 - 3.1e-19 68.8 2.5 1.9e-17 63.1 2.6 3.4 2 1 0 2 2 2 1 DKCLD (NUC011) domain UPF0113 PF03657.13 CRK15746.1 - 0.00079 19.6 0.0 0.0019 18.4 0.0 1.6 1 0 0 1 1 1 1 UPF0113 PUA domain p450 PF00067.22 CRK15747.1 - 4.6e-48 164.1 0.0 6.4e-48 163.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 LTV PF04180.14 CRK15749.1 - 8.2e-125 417.5 11.0 8.2e-125 417.5 11.0 2.5 3 0 0 3 3 3 1 Low temperature viability protein SAC3_GANP PF03399.16 CRK15749.1 - 2.3e-93 312.8 0.0 3.5e-93 312.2 0.0 1.3 1 0 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 CRK15749.1 - 0.00052 20.0 0.0 0.0014 18.6 0.0 1.6 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family Rep_fac_C PF08542.11 CRK15750.1 - 1.5e-21 76.6 0.0 3.1e-21 75.6 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain MMR_HSR1 PF01926.23 CRK15750.1 - 4.4e-17 62.2 0.7 7.3e-15 55.0 0.0 3.4 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA PF00004.29 CRK15750.1 - 9.8e-13 48.7 0.2 2.1e-10 41.1 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 CRK15750.1 - 1.5e-11 44.4 0.0 8.7e-08 32.1 0.0 2.7 1 1 1 2 2 2 2 DNA polymerase III, delta subunit FeoB_N PF02421.18 CRK15750.1 - 2.5e-08 33.6 0.5 1.5e-05 24.6 0.1 2.8 3 0 0 3 3 3 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CRK15750.1 - 3.9e-08 33.4 0.0 0.0022 17.9 0.0 3.4 3 0 0 3 3 3 1 RsgA GTPase AAA_14 PF13173.6 CRK15750.1 - 1.2e-06 28.6 0.1 5.7e-06 26.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 CRK15750.1 - 2.3e-05 23.5 0.2 0.019 13.9 0.0 2.7 3 0 0 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 CRK15750.1 - 2.9e-05 24.5 10.4 0.00076 19.9 0.0 4.9 2 2 2 4 4 4 1 AAA ATPase domain RuvB_N PF05496.12 CRK15750.1 - 4.7e-05 23.2 0.3 0.00055 19.7 0.0 2.6 3 0 0 3 3 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CRK15750.1 - 7.6e-05 23.0 0.2 0.41 10.9 0.0 3.8 3 1 1 4 4 3 1 AAA domain Viral_helicase1 PF01443.18 CRK15750.1 - 0.00033 20.5 0.0 0.0006 19.6 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.11 CRK15750.1 - 0.0011 18.9 0.0 0.0023 17.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 CRK15750.1 - 0.0037 17.0 0.0 0.67 9.6 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 CRK15750.1 - 0.0037 17.8 0.1 3.6 8.1 0.0 3.3 3 0 0 3 3 3 1 AAA domain Rad17 PF03215.15 CRK15750.1 - 0.0047 16.9 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_24 PF13479.6 CRK15750.1 - 0.0049 16.6 0.1 0.4 10.4 0.0 2.7 3 0 0 3 3 2 1 AAA domain Mg_chelatase PF01078.21 CRK15750.1 - 0.0084 15.5 0.1 0.1 12.0 0.0 2.6 2 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI TniB PF05621.11 CRK15750.1 - 0.0094 15.4 0.1 6.5 6.1 0.0 3.3 3 0 0 3 3 3 0 Bacterial TniB protein DNA_pol3_delta PF06144.13 CRK15750.1 - 0.01 15.7 0.2 0.054 13.3 0.0 2.0 2 0 0 2 2 2 1 DNA polymerase III, delta subunit RNA_helicase PF00910.22 CRK15750.1 - 0.011 16.1 0.0 3 8.3 0.0 3.0 2 1 0 2 2 2 0 RNA helicase AIG1 PF04548.16 CRK15750.1 - 0.017 14.5 0.1 0.034 13.5 0.1 1.5 1 0 0 1 1 1 0 AIG1 family KTI12 PF08433.10 CRK15750.1 - 0.019 14.4 0.3 0.087 12.3 0.0 2.1 2 0 0 2 2 2 0 Chromatin associated protein KTI12 cobW PF02492.19 CRK15750.1 - 0.023 14.3 0.9 6.3 6.4 0.0 2.9 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_assoc_2 PF16193.5 CRK15750.1 - 0.027 14.8 0.0 0.13 12.7 0.0 2.2 1 0 0 1 1 1 0 AAA C-terminal domain Thymidylate_kin PF02223.17 CRK15750.1 - 0.034 13.8 0.1 2.3 7.8 0.0 2.5 2 0 0 2 2 2 0 Thymidylate kinase NTPase_1 PF03266.15 CRK15750.1 - 0.036 14.0 0.2 0.17 11.8 0.0 2.3 3 0 0 3 3 1 0 NTPase AAA_19 PF13245.6 CRK15750.1 - 0.04 14.2 0.2 0.15 12.4 0.0 2.0 2 0 0 2 2 1 0 AAA domain SAPS PF04499.15 CRK15750.1 - 0.048 12.4 3.1 0.08 11.7 3.1 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein ABC_tran PF00005.27 CRK15750.1 - 0.05 14.1 0.4 11 6.5 0.0 2.8 2 0 0 2 2 2 0 ABC transporter AAA_11 PF13086.6 CRK15750.1 - 0.057 13.2 0.0 0.057 13.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 CRK15750.1 - 0.089 12.1 0.0 2.3 7.5 0.1 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family DEAD PF00270.29 CRK15750.1 - 0.13 12.1 0.1 2.7 7.7 0.0 2.3 1 1 1 2 2 2 0 DEAD/DEAH box helicase Dynamin_N PF00350.23 CRK15750.1 - 0.13 12.3 0.1 0.13 12.3 0.1 3.1 3 0 0 3 3 2 0 Dynamin family DUF5523 PF17661.1 CRK15750.1 - 0.91 9.2 9.9 1.6 8.3 9.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Paf1 PF03985.13 CRK15750.1 - 6.4 5.7 13.3 9.2 5.1 13.3 1.2 1 0 0 1 1 1 0 Paf1 DUF3539 PF12058.8 CRK15751.1 - 0.058 13.5 0.1 0.077 13.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3539) DUF3089 PF11288.8 CRK15751.1 - 0.094 12.2 0.1 0.097 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Bacteriocin_IIc PF10439.9 CRK15751.1 - 0.66 10.1 5.8 0.81 9.8 4.4 1.7 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide UreF PF01730.16 CRK15752.1 - 1.7e-20 73.9 1.7 1.7e-20 73.9 1.7 1.5 2 0 0 2 2 2 1 UreF Acyl-CoA_dh_2 PF08028.11 CRK15752.1 - 0.0087 16.3 0.3 0.021 15.1 0.3 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Phage_lysis PF03245.13 CRK15752.1 - 0.04 14.0 0.1 0.04 14.0 0.1 2.3 2 1 0 2 2 2 0 Bacteriophage Rz lysis protein DUF429 PF04250.13 CRK15752.1 - 0.051 13.4 0.5 0.09 12.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF429) Swi5 PF07061.11 CRK15752.1 - 0.26 11.4 1.4 0.55 10.3 1.4 1.5 1 0 0 1 1 1 0 Swi5 THOC7 PF05615.13 CRK15752.1 - 0.38 11.0 3.3 0.65 10.3 3.3 1.2 1 0 0 1 1 1 0 Tho complex subunit 7 Med21 PF11221.8 CRK15752.1 - 0.47 10.7 2.2 0.91 9.8 2.2 1.4 1 0 0 1 1 1 0 Subunit 21 of Mediator complex Torus PF16131.5 CRK15753.1 - 1.3e-45 154.5 0.1 3.3e-45 153.2 0.1 1.7 1 0 0 1 1 1 1 Torus domain RRM_1 PF00076.22 CRK15753.1 - 3e-07 30.1 0.0 5.5e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 CRK15753.1 - 0.00013 21.8 0.6 0.00013 21.8 0.6 1.9 2 0 0 2 2 2 1 Zinc finger domain Nup35_RRM_2 PF14605.6 CRK15753.1 - 0.0089 16.0 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.24 CRK15753.1 - 0.0097 15.8 0.7 0.021 14.7 0.7 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) MMR_HSR1_Xtn PF16897.5 CRK15754.1 - 2.3e-35 120.8 1.7 7.2e-35 119.2 0.5 2.1 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 CRK15754.1 - 9.4e-22 76.8 0.1 1.8e-21 75.9 0.1 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 CRK15754.1 - 1.8e-20 73.2 0.2 4.7e-20 71.8 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CRK15754.1 - 1.4e-12 47.4 0.0 2.3e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 CRK15754.1 - 0.00031 20.8 2.9 0.051 13.6 0.0 2.6 2 1 1 3 3 3 2 Dynamin family MeaB PF03308.16 CRK15754.1 - 0.066 12.2 0.2 0.16 10.9 0.1 1.7 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MCM PF00493.23 CRK15754.1 - 0.11 11.6 0.0 0.24 10.5 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain Spo12 PF05032.12 CRK15755.1 - 8.3e-16 57.6 0.6 2e-15 56.4 0.6 1.7 1 0 0 1 1 1 1 Spo12 family SAM_2 PF07647.17 CRK15758.1 - 3.1e-06 27.2 0.0 6.1e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RNA_lig_T4_1 PF09511.10 CRK15758.1 - 0.021 14.7 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 RNA ligase PH PF00169.29 CRK15759.1 - 4.3e-10 40.1 0.0 0.0023 18.4 0.0 3.4 2 2 0 2 2 2 2 PH domain SAM_2 PF07647.17 CRK15759.1 - 1.2e-05 25.3 0.0 2.9e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_9 PF15410.6 CRK15759.1 - 0.0058 17.0 0.1 6.4 7.2 0.0 2.4 2 0 0 2 2 2 2 Pleckstrin homology domain 3HCDH_RFF PF18321.1 CRK15759.1 - 0.047 14.1 2.1 8.1 7.0 0.1 2.6 2 0 0 2 2 2 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain RNA_lig_T4_1 PF09511.10 CRK15759.1 - 0.091 12.6 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 RNA ligase Sod_Fe_C PF02777.18 CRK15760.1 - 2e-20 72.9 0.0 5.9e-07 29.6 0.0 3.4 3 0 0 3 3 3 3 Iron/manganese superoxide dismutases, C-terminal domain Rota_Capsid_VP6 PF00980.17 CRK15760.1 - 0.0041 16.1 0.1 1.1 8.1 0.0 2.1 2 0 0 2 2 2 2 Rotavirus major capsid protein VP6 Sod_Fe_N PF00081.22 CRK15760.1 - 0.026 15.0 0.2 0.038 14.5 0.2 1.3 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, alpha-hairpin domain APH PF01636.23 CRK15762.1 - 2.3e-06 27.7 0.3 6.9e-06 26.2 0.3 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Stig1 PF04885.13 CRK15763.1 - 2.3e-50 170.7 327.1 0.00083 19.9 16.8 21.1 9 4 10 21 21 21 20 Stigma-specific protein, Stig1 Topoisom_I_N PF02919.15 CRK15765.1 - 1.7e-89 298.9 8.5 1.7e-89 298.9 8.5 1.8 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.20 CRK15765.1 - 5.5e-81 271.2 4.3 5.5e-81 271.2 4.3 1.5 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core DCP2 PF05026.13 CRK15765.1 - 0.061 13.7 0.0 0.21 12.0 0.0 1.9 1 0 0 1 1 1 0 Dcp2, box A domain 2OG-FeII_Oxy PF03171.20 CRK15766.1 - 1.3e-11 44.8 0.0 2e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Peptidase_M18 PF02127.15 CRK15767.1 - 2.2e-65 221.1 0.0 2.6e-65 220.9 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Keratin PF02422.16 CRK15768.1 - 0.088 12.5 0.1 0.28 10.9 0.0 1.7 1 1 1 2 2 2 0 Keratin FtsJ PF01728.19 CRK15769.1 - 1.6e-33 116.3 0.0 1.9e-33 116.0 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 CRK15769.1 - 7.8e-16 58.3 0.0 1.3e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3381) GXGXG PF01493.19 CRK15805.1 - 1.9e-49 167.8 3.4 1.9e-49 167.8 3.4 1.5 2 0 0 2 2 2 1 GXGXG motif DUF202 PF02656.15 CRK15805.1 - 3.8e-13 49.7 3.3 1.1e-12 48.2 3.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF202) PGI PF00342.19 CRK15806.1 - 1e-141 472.9 0.5 1.2e-141 472.6 0.5 1.1 1 0 0 1 1 1 1 Phosphoglucose isomerase XRN_N PF03159.18 CRK15809.1 - 3.7e-65 219.7 0.1 4.4e-65 219.5 0.1 1.0 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus DUF2533 PF10752.9 CRK15809.1 - 0.018 15.5 0.1 0.035 14.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2533) SPC22 PF04573.12 CRK15810.1 - 2.1e-40 138.0 0.8 2.2e-39 134.7 0.8 1.9 1 1 0 1 1 1 1 Signal peptidase subunit DUF2457 PF10446.9 CRK15811.1 - 1.7 7.7 6.7 1.7 7.7 6.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF1279 PF06916.13 CRK15812.1 - 0.17 12.4 0.1 0.34 11.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1279) DnaJ PF00226.31 CRK15813.1 - 8.8e-19 67.4 1.4 1.5e-18 66.7 1.4 1.4 1 0 0 1 1 1 1 DnaJ domain DUF456 PF04306.13 CRK15813.1 - 0.0079 16.5 1.9 0.012 15.9 1.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF456) Bacteriocin_IIc PF10439.9 CRK15813.1 - 0.053 13.6 5.6 0.12 12.6 5.6 1.6 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide GMC_oxred_N PF00732.19 CRK15814.1 - 2.7e-14 53.2 0.0 3.3e-14 52.9 0.0 1.0 1 0 0 1 1 1 1 GMC oxidoreductase RgpF PF05045.12 CRK15815.1 - 0.17 10.6 0.0 0.38 9.5 0.0 1.5 2 0 0 2 2 2 0 Rhamnan synthesis protein F Apolipoprotein PF01442.18 CRK15816.1 - 0.00052 19.9 0.1 0.0011 18.9 0.1 1.5 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 CRK15816.1 - 0.0058 16.7 8.8 0.56 10.2 0.2 2.5 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus Mitofilin PF09731.9 CRK15816.1 - 0.0069 15.3 0.2 0.0086 15.0 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial inner membrane protein ApoO PF09769.9 CRK15816.1 - 0.061 13.3 1.4 1.9 8.5 0.2 2.4 2 1 0 2 2 2 0 Apolipoprotein O IF-2 PF11987.8 CRK15816.1 - 0.091 12.9 3.5 0.31 11.2 0.8 2.7 2 1 1 3 3 3 0 Translation-initiation factor 2 HSCB_C PF07743.13 CRK15816.1 - 0.16 12.5 2.2 5 7.7 0.2 2.6 2 1 0 2 2 2 0 HSCB C-terminal oligomerisation domain Gp-FAR-1 PF05823.12 CRK15816.1 - 0.23 11.8 0.9 1.3 9.3 0.4 2.1 1 1 2 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) T7SS_ESX_EspC PF10824.8 CRK15816.1 - 7.4 7.1 12.4 3.9 8.0 1.4 3.0 1 1 3 4 4 4 0 Excreted virulence factor EspC, type VII ESX diderm LPMO_10 PF03067.15 CRK15817.1 - 8e-07 29.9 1.1 1.3e-06 29.2 1.1 1.3 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading HRXXH PF13933.6 CRK15818.1 - 5.8e-102 340.4 0.0 7.5e-102 340.1 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Aspzincin_M35 PF14521.6 CRK15818.1 - 1.3e-05 25.8 0.6 2.2e-05 25.0 0.0 1.7 2 0 0 2 2 2 1 Lysine-specific metallo-endopeptidase Sporozoite_P67 PF05642.11 CRK15818.1 - 0.021 13.0 0.1 0.022 12.9 0.1 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen ArdA PF07275.11 CRK15818.1 - 0.12 12.9 0.0 0.19 12.3 0.0 1.3 1 0 0 1 1 1 0 Antirestriction protein (ArdA) NPP1 PF05630.11 CRK15819.1 - 1.6e-56 191.6 0.0 1.8e-56 191.4 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Auxin_BP PF02041.16 CRK15819.1 - 0.21 11.2 0.0 0.3 10.7 0.0 1.2 1 0 0 1 1 1 0 Auxin binding protein Zn_clus PF00172.18 CRK15820.1 - 6.5e-10 39.0 7.3 1.1e-09 38.3 7.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RTA1 PF04479.13 CRK15821.1 - 1.8e-54 184.5 1.4 1.8e-54 184.5 1.4 1.5 1 1 1 2 2 2 1 RTA1 like protein Zn_clus PF00172.18 CRK15824.1 - 0.00051 20.1 9.0 0.00081 19.5 9.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 CRK15824.1 - 0.014 14.4 0.1 0.027 13.5 0.1 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain Zip PF02535.22 CRK15824.1 - 1.2 8.3 8.5 0.35 10.1 3.5 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter SUIM_assoc PF16619.5 CRK15824.1 - 1.5 9.0 14.1 7.6 6.7 14.1 2.2 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 RhoGAP PF00620.27 CRK15825.1 - 1.1e-41 142.1 0.1 3.5e-41 140.6 0.1 1.9 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 CRK15825.1 - 7.7e-12 45.6 0.0 1.6e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 PH domain CorA PF01544.18 CRK15825.1 - 2.3e-10 40.3 1.1 2.3e-10 40.3 1.1 2.2 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein PH_8 PF15409.6 CRK15825.1 - 0.12 12.7 0.0 0.56 10.5 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain Lactamase_B PF00753.27 CRK15827.1 - 0.00014 21.9 0.0 0.00018 21.6 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Aldo_ket_red PF00248.21 CRK15828.1 - 8.9e-52 176.1 0.0 1e-51 175.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AMP-binding PF00501.28 CRK15829.1 - 1.6e-63 214.8 0.0 2.5e-63 214.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 CRK15829.1 - 1.2e-26 93.4 0.0 1.6e-26 93.0 0.0 1.1 1 0 0 1 1 1 1 Condensation domain NAD_binding_4 PF07993.12 CRK15829.1 - 2.1e-16 59.9 0.0 4.4e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 CRK15829.1 - 2.3e-11 43.9 0.0 5.8e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 CRK15829.1 - 4.8e-07 29.5 0.0 1e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.6 CRK15829.1 - 0.0005 21.0 0.0 0.004 18.1 0.0 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.16 CRK15830.1 - 2.5e-38 131.9 47.3 2.5e-38 131.9 47.3 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK15830.1 - 3e-08 33.0 10.5 3e-08 33.0 10.5 2.4 3 0 0 3 3 3 1 Sugar (and other) transporter Sugar_tr PF00083.24 CRK15831.1 - 6.4e-99 331.8 20.4 7.4e-99 331.6 20.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK15831.1 - 7e-40 137.0 39.8 2.2e-33 115.7 19.4 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily EGF PF00008.27 CRK15831.1 - 4 7.8 5.2 3 8.2 1.3 2.7 3 0 0 3 3 3 0 EGF-like domain Acyl_transf_1 PF00698.21 CRK15832.1 - 9.6e-44 150.2 0.0 1.8e-43 149.2 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Condensation PF00668.20 CRK15832.1 - 5.2e-42 144.1 0.0 8.3e-42 143.4 0.0 1.2 1 0 0 1 1 1 1 Condensation domain KR PF08659.10 CRK15832.1 - 6.6e-37 127.2 2.5 3.7e-20 72.6 0.1 2.6 1 1 1 2 2 2 2 KR domain PS-DH PF14765.6 CRK15832.1 - 1.2e-15 57.6 1.4 2.1e-15 56.7 0.2 2.1 2 0 0 2 2 2 1 Polyketide synthase dehydratase PP-binding PF00550.25 CRK15832.1 - 0.00032 21.0 0.0 0.00072 19.9 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site SAT PF16073.5 CRK15832.1 - 0.00091 19.0 0.1 0.0041 16.9 0.0 2.2 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Glyco_hydro_14 PF01373.17 CRK15832.1 - 0.022 13.7 0.0 0.036 13.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 14 adh_short PF00106.25 CRK15832.1 - 0.072 12.5 0.7 0.2 11.1 0.0 2.1 2 0 0 2 2 2 0 short chain dehydrogenase Thioesterase PF00975.20 CRK15833.1 - 1.4e-19 71.2 0.0 1.3e-18 68.0 0.0 2.0 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_6 PF12697.7 CRK15833.1 - 5.2e-09 37.0 8.0 7.1e-09 36.6 8.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 CRK15833.1 - 0.028 14.2 0.0 0.04 13.7 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 CRK15833.1 - 0.093 12.3 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold ketoacyl-synt PF00109.26 CRK15834.1 - 7.8e-64 215.7 0.0 1.2e-62 211.8 0.0 2.3 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 CRK15834.1 - 2.1e-30 105.2 0.5 3.2e-29 101.3 0.5 2.2 1 1 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 CRK15834.1 - 1.7e-11 44.6 0.0 3.3e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 CRK15834.1 - 0.0065 15.9 0.1 0.01 15.2 0.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 CRK15834.1 - 0.016 15.0 0.1 0.052 13.4 0.1 1.9 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III adh_short_C2 PF13561.6 CRK15836.1 - 3.7e-24 85.6 0.6 3.6e-18 66.0 0.1 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRK15836.1 - 2.4e-18 66.3 0.0 6.8e-10 38.7 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 CRK15836.1 - 0.00043 20.2 0.7 0.001 19.0 0.6 1.7 1 1 1 2 2 2 1 KR domain MFS_1 PF07690.16 CRK15837.1 - 1.6e-60 205.0 77.6 1.1e-29 103.5 22.8 3.6 3 2 0 3 3 3 3 Major Facilitator Superfamily TRI12 PF06609.13 CRK15837.1 - 3.1e-17 62.3 27.8 2.9e-16 59.0 18.4 2.5 2 1 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 CRK15837.1 - 1.1e-13 50.9 20.5 2.4e-11 43.2 6.0 3.9 3 1 1 4 4 4 2 Sugar (and other) transporter MFS_2 PF13347.6 CRK15837.1 - 2.2e-07 29.8 39.3 2.4e-05 23.1 0.5 4.3 4 0 0 4 4 4 4 MFS/sugar transport protein Pkinase PF00069.25 CRK15838.1 - 2.9e-14 53.1 0.0 5.6e-10 39.0 0.0 2.3 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CRK15838.1 - 0.00021 20.7 0.0 0.046 13.0 0.0 2.8 3 0 0 3 3 3 2 Protein tyrosine kinase Halo_GVPC PF05465.13 CRK15839.1 - 0.49 10.7 1.9 7.5 6.9 1.9 2.2 1 1 1 2 2 2 0 Halobacterial gas vesicle protein C (GVPC) repeat Ank_2 PF12796.7 CRK15841.1 - 3.3e-20 72.5 1.6 1.3e-15 57.7 0.2 1.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CRK15841.1 - 8.7e-18 62.6 0.3 5.5e-06 26.3 0.1 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 CRK15841.1 - 8.1e-15 55.0 0.3 2e-09 37.8 0.2 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 CRK15841.1 - 9.8e-14 51.1 1.5 0.00023 21.5 0.7 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 CRK15841.1 - 1e-12 48.0 1.4 4.5e-07 30.0 0.2 2.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Thymidylate_kin PF02223.17 CRK15841.1 - 0.067 12.9 0.1 0.43 10.2 0.2 1.9 2 0 0 2 2 2 0 Thymidylate kinase adh_short PF00106.25 CRK15842.1 - 2e-22 79.6 0.0 3.5e-22 78.8 0.0 1.3 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK15842.1 - 3.9e-17 62.6 0.0 4.6e-17 62.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK15842.1 - 0.0003 20.8 0.1 0.00039 20.4 0.1 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 CRK15842.1 - 0.16 11.4 0.0 1.5 8.1 0.0 2.0 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase ICL PF00463.21 CRK15845.1 - 2e-56 191.6 1.1 2.2e-56 191.4 1.1 1.0 1 0 0 1 1 1 1 Isocitrate lyase family Mon1 PF03164.14 CRK15847.1 - 1.1e-41 143.2 0.0 1.2e-41 143.1 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 RFX5_N PF18326.1 CRK15847.1 - 0.057 13.2 0.8 0.1 12.3 0.8 1.4 1 0 0 1 1 1 0 RFX5 N-terminal domain Methyltransf_11 PF08241.12 CRK15848.1 - 2.3e-14 53.8 0.0 4.6e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK15848.1 - 2.1e-06 28.3 0.0 6.8e-06 26.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK15848.1 - 0.0058 17.4 0.0 0.014 16.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK15848.1 - 0.022 14.5 0.0 0.055 13.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain ECH_1 PF00378.20 CRK15863.1 - 1.6e-10 40.7 0.0 2.4e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CRK15863.1 - 0.00076 19.1 0.0 0.00092 18.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase MaoC_dehydratas PF01575.19 CRK15865.1 - 5.5e-06 26.0 0.0 8.3e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain LeuA_dimer PF08502.10 CRK15880.1 - 1.1e-23 83.5 0.1 2.2e-23 82.6 0.1 1.5 1 1 0 1 1 1 1 LeuA allosteric (dimerisation) domain Pkinase PF00069.25 CRK15893.1 - 4.7e-15 55.7 0.0 5.3e-15 55.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK15893.1 - 6.2e-13 48.6 0.0 7.1e-13 48.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase AAA PF00004.29 CRK15895.1 - 4.4e-40 137.2 0.0 9.7e-40 136.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Ras PF00071.22 CRK15895.1 - 9.2e-10 38.4 0.0 1.8e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Ras family AAA_lid_3 PF17862.1 CRK15895.1 - 2.9e-09 36.6 0.1 8e-09 35.2 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 CRK15895.1 - 0.0009 19.2 0.0 0.005 16.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CRK15895.1 - 0.0096 16.3 0.0 0.78 10.1 0.0 2.6 1 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 CRK15895.1 - 0.011 15.5 0.0 0.043 13.6 0.0 2.0 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 CRK15895.1 - 0.016 15.4 0.0 0.031 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Rad17 PF03215.15 CRK15895.1 - 0.02 14.8 0.0 0.046 13.6 0.0 1.6 1 1 0 1 1 1 0 Rad17 P-loop domain Mg_chelatase PF01078.21 CRK15895.1 - 0.051 13.0 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 CRK15895.1 - 0.1 12.9 0.0 0.86 9.9 0.0 2.2 1 1 1 2 2 2 0 AAA domain RNA_helicase PF00910.22 CRK15895.1 - 0.18 12.2 0.0 0.43 11.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Fungal_trans_2 PF11951.8 CRK15896.1 - 0.0095 14.8 0.1 0.013 14.3 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cys_Met_Meta_PP PF01053.20 CRK15897.1 - 2.5e-43 148.1 0.0 2.7e-43 147.9 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme zf-P11 PF03854.14 CRK15900.1 - 0.0044 16.6 0.1 0.0072 16.0 0.1 1.3 1 0 0 1 1 1 1 P-11 zinc finger COX16 PF14138.6 CRK15901.1 - 1.3e-35 121.7 0.2 1.6e-35 121.4 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 UNC119_bdg PF15435.6 CRK15901.1 - 0.16 11.5 0.1 0.2 11.2 0.1 1.1 1 0 0 1 1 1 0 UNC119-binding protein C5orf30 homologue UPF0561 PF10573.9 CRK15902.1 - 0.033 14.3 1.8 2.8 8.1 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0561 Mab-21 PF03281.14 CRK15902.1 - 0.081 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Mab-21 protein DAO PF01266.24 CRK15903.1 - 4.2e-40 138.4 0.9 5e-40 138.2 0.9 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 CRK15903.1 - 0.0027 18.2 0.0 0.061 13.9 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CRK15903.1 - 0.014 14.7 0.0 1.2 8.3 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CRK15903.1 - 0.021 15.1 0.0 0.062 13.5 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain adh_short PF00106.25 CRK15904.1 - 2.3e-35 121.8 0.1 4.7e-34 117.6 0.1 2.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK15904.1 - 8.9e-26 90.9 0.1 5e-25 88.4 0.1 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase CBFD_NFYB_HMF PF00808.23 CRK15904.1 - 4.2e-17 62.2 0.7 1.1e-16 60.9 0.7 1.8 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone KR PF08659.10 CRK15904.1 - 1.2e-05 25.3 0.6 0.0023 17.9 0.5 2.6 2 1 0 2 2 2 1 KR domain Histone PF00125.24 CRK15904.1 - 9.3e-05 22.8 0.7 0.00021 21.6 0.0 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 NAD_binding_10 PF13460.6 CRK15904.1 - 0.00065 19.6 0.6 0.0021 18.0 0.6 1.9 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 CRK15904.1 - 0.12 11.8 0.1 0.71 9.3 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family PRP38 PF03371.15 CRK15906.1 - 6e-50 169.5 0.0 7.5e-50 169.2 0.0 1.1 1 0 0 1 1 1 1 PRP38 family DUF5421 PF17458.2 CRK15906.1 - 0.0054 16.2 1.7 0.0074 15.7 1.7 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5421) ANAPC_CDC26 PF10471.9 CRK15906.1 - 0.31 11.9 11.6 0.63 10.9 11.6 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 RP-C_C PF11800.8 CRK15906.1 - 0.77 9.8 4.1 1.4 9.0 4.1 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region CDC45 PF02724.14 CRK15906.1 - 6.5 4.9 7.8 7.3 4.7 7.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Amidase PF01425.21 CRK15907.1 - 1.6e-117 393.3 0.0 2.3e-117 392.8 0.0 1.2 1 0 0 1 1 1 1 Amidase Sugar_tr PF00083.24 CRK15907.1 - 8.7e-66 222.6 14.5 1e-65 222.4 14.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK15907.1 - 8.7e-18 64.4 18.5 8.7e-18 64.4 18.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily 2-Hacid_dh_C PF02826.19 CRK15908.1 - 3.2e-46 156.9 0.0 3.9e-46 156.6 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CRK15908.1 - 7.5e-08 32.1 0.0 8.5e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 CRK15908.1 - 7.1e-05 23.0 0.0 9.7e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase HTH_1 PF00126.27 CRK15908.1 - 0.00093 19.1 0.2 0.0022 17.9 0.2 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix protein, lysR family Metallophos PF00149.28 CRK15909.1 - 3.4e-09 37.5 1.0 7.1e-09 36.5 1.0 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase AlaDh_PNT_C PF01262.21 CRK15910.1 - 0.24 10.7 0.0 0.36 10.1 0.0 1.1 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain SLC35F PF06027.12 CRK15911.1 - 1.1e-93 314.1 23.9 1.1e-93 314.1 23.9 1.2 1 1 0 1 1 1 1 Solute carrier family 35 EamA PF00892.20 CRK15911.1 - 3.8e-06 27.1 40.6 0.0002 21.6 14.5 2.2 2 0 0 2 2 2 2 EamA-like transporter family CRT-like PF08627.10 CRK15911.1 - 4.3e-06 25.9 12.4 6.2e-06 25.4 12.4 1.2 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like FUSC-like PF12805.7 CRK15911.1 - 0.3 10.1 9.5 0.049 12.7 1.8 2.3 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS CALM_bind PF16025.5 CRK15912.1 - 0.089 13.3 3.8 0.19 12.2 3.8 1.6 1 0 0 1 1 1 0 Calcium-dependent calmodulin binding AhpC-TSA_2 PF13911.6 CRK15913.1 - 6.6e-06 26.2 0.0 1.2e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 CRK15913.1 - 0.0057 16.6 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family PAP_assoc PF03828.19 CRK15914.1 - 1.5e-16 60.4 0.1 3.5e-16 59.1 0.1 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 CRK15914.1 - 1.6e-05 25.1 0.0 2.8e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF3105 PF11303.8 CRK15914.1 - 0.018 15.2 0.3 0.045 13.9 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3105) Polbeta PF18765.1 CRK15914.1 - 0.048 13.8 0.0 0.089 12.9 0.0 1.4 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase FHA PF00498.26 CRK15917.1 - 5.9e-16 58.6 0.2 2.2e-15 56.7 0.0 2.1 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 CRK15917.1 - 0.0021 18.3 0.0 0.0051 17.1 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Macoilin PF09726.9 CRK15917.1 - 0.0038 15.9 3.1 0.0038 15.9 3.1 3.2 3 0 0 3 3 3 1 Macoilin family YhfZ_C PF14503.6 CRK15917.1 - 0.065 12.8 2.3 0.11 12.0 0.0 2.1 2 0 0 2 2 2 0 YhfZ C-terminal domain CCDC144C PF14915.6 CRK15917.1 - 0.36 9.9 11.9 0.28 10.3 2.9 2.1 2 0 0 2 2 2 0 CCDC144C protein coiled-coil region GAS PF13851.6 CRK15917.1 - 0.49 9.7 14.3 0.064 12.6 3.7 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Vps51 PF08700.11 CRK15917.1 - 1.3 9.1 4.3 14 5.9 0.9 2.7 2 0 0 2 2 2 0 Vps51/Vps67 MetOD2 PF18548.1 CRK15917.1 - 1.7 8.8 5.8 0.63 10.2 0.4 2.6 2 1 1 3 3 3 0 Metanogen output domain 2 DUF4047 PF13256.6 CRK15917.1 - 1.9 8.7 5.5 0.3 11.3 1.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) OEP PF02321.18 CRK15917.1 - 1.9 8.2 6.1 7.5 6.3 0.1 2.4 2 0 0 2 2 2 0 Outer membrane efflux protein TMPIT PF07851.13 CRK15917.1 - 2.5 7.3 6.9 5.7 6.1 0.3 2.1 2 0 0 2 2 2 0 TMPIT-like protein XhlA PF10779.9 CRK15917.1 - 2.9 8.2 9.7 3 8.1 0.4 2.5 2 0 0 2 2 2 0 Haemolysin XhlA DUF3584 PF12128.8 CRK15917.1 - 3.5 5.0 14.7 5.1 4.5 14.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Sec34 PF04136.15 CRK15917.1 - 3.7 7.4 7.4 5 7.0 1.4 2.2 2 0 0 2 2 2 0 Sec34-like family TMF_TATA_bd PF12325.8 CRK15917.1 - 4.3 7.6 15.1 1.9 8.7 3.8 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Sec8_exocyst PF04048.14 CRK15917.1 - 5.7 6.8 6.8 5.3 6.9 0.7 2.2 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain TPR_MLP1_2 PF07926.12 CRK15917.1 - 9.9 6.2 16.6 14 5.8 1.8 2.5 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Fungal_trans_2 PF11951.8 CRK15919.1 - 3.6e-22 78.7 0.0 5.2e-22 78.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Lustrin_cystein PF14625.6 CRK15920.1 - 0.12 12.7 8.8 1.7 9.1 8.8 2.1 1 1 1 2 2 2 0 Lustrin, cysteine-rich repeated domain PepSY_2 PF13670.6 CRK15920.1 - 0.14 12.2 0.0 0.21 11.6 0.0 1.2 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain ABC2_membrane PF01061.24 CRK15921.1 - 8.2e-41 139.7 15.0 8.2e-41 139.7 15.0 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 CRK15921.1 - 2.3e-32 112.4 0.0 1.6e-16 61.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 CRK15921.1 - 4.5e-32 109.8 0.4 1.3e-31 108.4 0.0 1.9 2 0 0 2 2 2 1 CDR ABC transporter ABC_trans_N PF14510.6 CRK15921.1 - 2e-14 54.0 0.0 4.2e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_29 PF13555.6 CRK15921.1 - 2.4e-07 30.4 1.4 0.00021 21.0 0.4 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.6 CRK15921.1 - 1.9e-06 27.6 0.5 1.9e-05 24.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CRK15921.1 - 1.9e-06 28.4 0.0 0.0027 18.1 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.6 CRK15921.1 - 3.3e-06 27.3 1.2 0.01 16.0 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.6 CRK15921.1 - 1.1e-05 26.0 0.0 0.0065 17.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 CRK15921.1 - 1.9e-05 24.6 0.0 0.00046 20.1 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 CRK15921.1 - 0.00034 20.5 0.1 0.13 12.1 0.0 2.9 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CRK15921.1 - 0.00041 19.8 0.0 0.49 9.8 0.0 3.0 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 CRK15921.1 - 0.0028 17.4 0.4 0.077 12.7 0.2 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 CRK15921.1 - 0.0033 17.3 0.3 0.16 11.9 0.0 2.7 3 0 0 3 3 2 1 NACHT domain AAA_22 PF13401.6 CRK15921.1 - 0.0037 17.5 0.0 1.4 9.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 CRK15921.1 - 0.006 15.7 8.7 0.015 14.5 8.7 1.6 1 0 0 1 1 1 1 ABC-2 family transporter protein Rad17 PF03215.15 CRK15921.1 - 0.011 15.7 0.0 0.29 11.1 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain PDR_assoc PF08370.11 CRK15921.1 - 0.011 15.5 4.5 0.02 14.6 0.6 2.8 2 0 0 2 2 2 0 Plant PDR ABC transporter associated AAA_23 PF13476.6 CRK15921.1 - 0.021 15.3 0.0 0.05 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 CRK15921.1 - 0.027 13.8 0.0 0.11 11.7 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin IstB_IS21 PF01695.17 CRK15921.1 - 0.031 14.0 0.0 2 8.1 0.0 2.7 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_28 PF13521.6 CRK15921.1 - 0.041 14.1 3.0 0.3 11.3 0.9 2.6 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 CRK15921.1 - 0.042 13.6 0.7 3.1 7.5 0.2 2.4 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 CRK15921.1 - 0.049 13.7 0.3 4.5 7.4 0.2 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 CRK15921.1 - 0.073 13.5 0.0 2.2 8.7 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA PF00004.29 CRK15921.1 - 0.11 13.0 0.0 5.5 7.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 CRK15921.1 - 0.12 11.9 4.4 0.34 10.5 1.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 CRK15921.1 - 0.16 12.4 0.1 7.9 6.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 CRK15921.1 - 0.19 10.8 0.2 12 4.9 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein Glyco_hydro_61 PF03443.14 CRK15922.1 - 2.8e-49 167.8 0.0 4.8e-49 167.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 TPR_12 PF13424.6 CRK15922.1 - 0.00061 20.0 1.5 0.0024 18.1 0.6 2.4 1 1 2 3 3 3 2 Tetratricopeptide repeat Helo_like_N PF17111.5 CRK15922.1 - 0.001 18.5 1.7 0.001 18.5 1.7 1.9 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins TPR_7 PF13176.6 CRK15922.1 - 0.0012 18.7 0.7 0.033 14.2 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.14 CRK15922.1 - 0.006 17.1 1.6 0.006 17.1 1.6 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_MalT PF17874.1 CRK15922.1 - 0.011 15.1 1.0 0.048 13.0 0.9 2.0 2 0 0 2 2 2 0 MalT-like TPR region TPR_19 PF14559.6 CRK15922.1 - 0.02 15.4 2.0 0.2 12.2 0.8 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 CRK15922.1 - 0.032 14.1 0.1 0.31 10.9 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 CRK15922.1 - 0.13 12.1 0.1 0.37 10.7 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Baculo_F PF12259.8 CRK15922.1 - 0.16 10.5 0.1 0.24 9.9 0.1 1.2 1 0 0 1 1 1 0 Baculovirus F protein TPR_2 PF07719.17 CRK15922.1 - 0.19 11.9 7.9 0.17 12.1 0.3 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 CRK15922.1 - 0.76 10.8 5.7 0.37 11.7 0.4 3.2 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 CRK15922.1 - 1.3 9.8 3.9 27 5.7 0.2 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat CENP-B_dimeris PF09026.10 CRK15922.1 - 2.6 8.5 5.5 2.2 8.7 3.4 1.9 2 0 0 2 2 2 0 Centromere protein B dimerisation domain MFS_1 PF07690.16 CRK15923.1 - 5.3e-34 117.7 7.1 5.3e-34 117.7 7.1 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK15923.1 - 7.2e-11 41.6 0.3 7.2e-11 41.6 0.3 2.4 2 1 1 3 3 3 1 Sugar (and other) transporter Glyco_hydro_88 PF07470.13 CRK15924.1 - 1.7e-92 310.1 3.9 2e-92 309.9 3.9 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_hydro_127 PF07944.12 CRK15924.1 - 0.0014 17.2 0.6 0.002 16.7 0.6 1.1 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 Glyco_hydro_76 PF03663.14 CRK15924.1 - 0.23 11.0 7.2 0.098 12.2 0.7 2.9 1 1 2 3 3 3 0 Glycosyl hydrolase family 76 MFS_1 PF07690.16 CRK15925.1 - 3.2e-27 95.4 28.3 4.5e-27 94.9 28.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_3_C PF01915.22 CRK15926.1 - 1.4e-41 142.7 0.0 2.5e-41 141.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 CRK15926.1 - 1.1e-37 130.1 0.0 1.7e-37 129.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 CRK15926.1 - 3.6e-23 81.4 0.4 7.8e-23 80.4 0.4 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF1761 PF08570.10 CRK15927.1 - 0.017 15.3 0.7 0.017 15.3 0.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1761) ABC_tran PF00005.27 CRK15928.1 - 2e-47 161.2 0.2 4.4e-26 92.0 0.0 4.4 2 2 1 3 3 3 3 ABC transporter AAA_21 PF13304.6 CRK15928.1 - 3.1e-14 53.5 5.7 0.0018 18.1 0.1 4.6 3 3 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CRK15928.1 - 2.6e-12 46.6 0.0 0.0014 18.2 0.0 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CRK15928.1 - 3.1e-10 40.9 1.7 3e-05 24.6 0.0 3.1 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 CRK15928.1 - 1.9e-07 31.1 0.0 0.0035 17.4 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CRK15928.1 - 2.9e-07 30.6 0.1 0.0024 17.8 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 CRK15928.1 - 3.8e-07 29.8 0.7 0.0057 16.4 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 CRK15928.1 - 8.1e-05 22.9 0.4 0.64 10.3 0.0 3.3 2 1 0 2 2 2 2 AAA domain Chromo PF00385.24 CRK15928.1 - 9.6e-05 22.2 2.1 9.6e-05 22.2 2.1 2.1 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_28 PF13521.6 CRK15928.1 - 0.00048 20.4 0.0 0.031 14.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 CRK15928.1 - 0.0013 18.6 3.2 0.16 11.6 0.1 2.6 3 0 0 3 3 2 1 AAA ATPase domain AAA_18 PF13238.6 CRK15928.1 - 0.0015 19.0 0.1 0.41 11.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CRK15928.1 - 0.002 18.5 0.1 3.3 8.1 0.0 2.6 2 0 0 2 2 2 1 RNA helicase NACHT PF05729.12 CRK15928.1 - 0.0029 17.5 0.2 2.1 8.2 0.0 2.9 3 0 0 3 3 2 1 NACHT domain AAA_33 PF13671.6 CRK15928.1 - 0.003 17.7 0.1 2.4 8.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 CRK15928.1 - 0.0031 18.0 0.0 5.8 7.3 0.0 2.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.17 CRK15928.1 - 0.0031 17.6 2.7 0.44 10.6 0.1 3.4 4 0 0 4 4 2 1 Helicase HerA, central domain SR-25 PF10500.9 CRK15928.1 - 0.0047 16.6 3.1 0.0091 15.6 3.1 1.4 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein AAA_13 PF13166.6 CRK15928.1 - 0.0055 15.4 0.2 1.8 7.1 0.0 2.8 3 0 0 3 3 3 1 AAA domain SbcCD_C PF13558.6 CRK15928.1 - 0.0056 16.9 0.8 3.1 8.1 0.0 3.6 3 2 0 3 3 2 1 Putative exonuclease SbcCD, C subunit MeaB PF03308.16 CRK15928.1 - 0.0062 15.6 0.3 1.6 7.6 0.1 2.5 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 CRK15928.1 - 0.0089 15.8 0.1 5 6.8 0.1 2.9 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 CRK15928.1 - 0.0089 15.8 1.1 0.56 9.9 0.2 2.7 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 CRK15928.1 - 0.012 15.7 0.1 0.4 10.7 0.0 3.0 3 0 0 3 3 3 0 Dynamin family Roc PF08477.13 CRK15928.1 - 0.016 15.4 0.0 5.3 7.3 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 CRK15928.1 - 0.017 14.9 0.0 0.81 9.4 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 CRK15928.1 - 0.023 15.1 0.2 2.5 8.5 0.0 3.1 3 0 0 3 3 2 0 AAA ATPase domain DUF3584 PF12128.8 CRK15928.1 - 0.027 12.0 0.7 3.1 5.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) AAA_27 PF13514.6 CRK15928.1 - 0.035 13.7 2.2 6.9 6.2 0.0 3.3 4 0 0 4 4 3 0 AAA domain NB-ARC PF00931.22 CRK15928.1 - 0.054 12.7 0.4 4.2 6.5 0.1 2.4 2 0 0 2 2 2 0 NB-ARC domain DUF815 PF05673.13 CRK15928.1 - 0.08 12.1 0.3 3.5 6.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Septin PF00735.18 CRK15928.1 - 0.081 12.2 0.0 11 5.2 0.0 2.4 2 0 0 2 2 2 0 Septin ALF PF03752.13 CRK15928.1 - 0.12 12.3 2.1 20 5.3 0.0 3.1 3 0 0 3 3 3 0 Short repeats of unknown function TsaE PF02367.17 CRK15928.1 - 0.13 12.3 0.6 20 5.2 0.2 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 CRK15928.1 - 0.14 12.2 0.0 5.6 7.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 CRK15928.1 - 0.17 11.8 0.7 22 4.9 0.4 2.8 2 0 0 2 2 2 0 NTPase cobW PF02492.19 CRK15928.1 - 0.35 10.5 1.2 25 4.4 0.1 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain CLP1_P PF16575.5 CRK15928.1 - 0.58 9.9 2.2 52 3.6 0.1 3.3 3 0 0 3 3 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop HEAT_2 PF13646.6 CRK15928.1 - 0.59 10.6 4.2 2.1 8.8 0.1 3.8 4 0 0 4 4 3 0 HEAT repeats AAA_7 PF12775.7 CRK15928.1 - 2 7.9 3.6 14 5.1 0.0 2.7 3 0 0 3 3 2 0 P-loop containing dynein motor region Glyco_trans_2_3 PF13632.6 CRK15929.1 - 8e-52 176.0 2.3 8e-52 176.0 2.3 2.2 2 1 1 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 CRK15929.1 - 3.7e-06 26.8 0.0 9.5e-06 25.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 CRK15929.1 - 0.00051 19.6 0.0 0.0011 18.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 CRK15929.1 - 0.0027 17.7 0.0 0.0052 16.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Pterin_bind PF00809.22 CRK15932.1 - 4.2e-35 121.6 0.1 5.7e-35 121.1 0.1 1.2 1 0 0 1 1 1 1 Pterin binding enzyme Arm PF00514.23 CRK15934.1 - 1.7e-94 307.4 15.7 4.1e-13 48.9 0.0 8.4 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 CRK15934.1 - 3.9e-23 81.5 9.2 4.5e-09 36.6 0.1 6.3 5 1 1 6 6 6 4 HEAT-like repeat Arm_3 PF16186.5 CRK15934.1 - 8.2e-23 79.7 5.9 1.2e-22 79.2 4.7 1.9 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_2 PF13646.6 CRK15934.1 - 3.3e-19 69.1 0.2 1.5e-08 34.9 0.0 5.2 1 1 5 6 6 6 4 HEAT repeats HEAT PF02985.22 CRK15934.1 - 9.6e-19 65.9 2.4 9.2e-06 25.5 0.0 7.1 8 0 0 8 8 8 4 HEAT repeat Arm_2 PF04826.13 CRK15934.1 - 1e-07 31.7 0.0 0.05 13.0 0.0 4.0 2 1 2 4 4 4 3 Armadillo-like V-ATPase_H_C PF11698.8 CRK15934.1 - 5.7e-05 23.2 0.0 1.7 8.8 0.0 4.4 3 2 2 5 5 5 2 V-ATPase subunit H Adaptin_N PF01602.20 CRK15934.1 - 0.0001 21.0 0.0 0.0079 14.8 0.0 2.6 1 1 0 2 2 2 1 Adaptin N terminal region Cnd1 PF12717.7 CRK15934.1 - 0.00075 19.6 0.0 0.74 9.8 0.0 2.7 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 CRK15934.1 - 0.002 18.6 2.9 0.99 10.3 0.3 4.6 4 1 0 4 4 4 1 PBS lyase HEAT-like repeat NopRA1 PF16201.5 CRK15934.1 - 0.029 13.9 0.0 3.9 7.0 0.0 3.7 2 2 3 5 5 5 0 Nucleolar pre-ribosomal-associated protein 1 RICTOR_V PF14668.6 CRK15934.1 - 0.075 13.3 5.0 4.9 7.5 0.1 4.8 3 2 3 6 6 6 0 Rapamycin-insensitive companion of mTOR, domain 5 Glycos_trans_3N PF02885.17 CRK15934.1 - 0.13 12.1 0.0 6.9 6.6 0.0 2.9 3 0 0 3 3 3 0 Glycosyl transferase family, helical bundle domain PLDc PF00614.22 CRK15936.1 - 2e-08 34.1 0.2 4.4e-08 33.0 0.2 1.6 1 0 0 1 1 1 1 Phospholipase D Active site motif PLDc_2 PF13091.6 CRK15936.1 - 8.1e-05 22.5 0.1 0.00021 21.2 0.0 1.7 2 0 0 2 2 2 1 PLD-like domain Tcp11 PF05794.13 CRK15942.1 - 3.5e-64 217.5 0.0 4.3e-64 217.3 0.0 1.0 1 0 0 1 1 1 1 T-complex protein 11 NAM-associated PF14303.6 CRK15958.1 - 4.6 7.9 7.6 0.16 12.7 1.1 1.8 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain Herpes_LMP1 PF05297.11 CRK15975.1 - 6.2 5.9 6.4 9.9 5.2 6.4 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) IlvC PF01450.19 CRK15977.1 - 1e-41 142.6 0.0 1.3e-41 142.2 0.0 1.1 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvN PF07991.12 CRK15977.1 - 1.7e-14 53.7 0.0 2.7e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain C2 PF00168.30 CRK15981.1 - 0.0018 18.5 0.0 0.0035 17.6 0.0 1.7 1 1 0 1 1 1 1 C2 domain DUF1981 PF09324.10 CRK15983.1 - 1.6e-36 124.0 3.3 2.2e-34 117.1 0.2 3.2 3 0 0 3 3 3 2 Domain of unknown function (DUF1981) RIH_assoc PF08454.11 CRK15983.1 - 0.1 12.5 0.4 0.51 10.2 0.1 2.1 2 0 0 2 2 2 0 RyR and IP3R Homology associated DUF4828 PF16110.5 CRK15985.1 - 0.11 13.0 0.6 0.17 12.4 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4828) DUF3425 PF11905.8 CRK15986.1 - 6.6e-07 29.3 0.5 1.3e-06 28.4 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 CRK15986.1 - 1.1e-05 25.4 2.1 1.1e-05 25.4 2.1 3.1 4 0 0 4 4 4 2 bZIP transcription factor Zn_clus PF00172.18 CRK15987.1 - 3.7e-06 27.0 9.4 6.3e-06 26.2 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PNP_UDP_1 PF01048.20 CRK15988.1 - 1.4e-05 24.5 0.2 2.9e-05 23.4 0.1 1.6 1 1 1 2 2 2 1 Phosphorylase superfamily Hemerythrin PF01814.23 CRK15990.1 - 1.2e-06 29.2 1.5 3e-06 27.9 1.2 1.8 1 1 1 2 2 2 1 Hemerythrin HHE cation binding domain Strumpellin PF10266.9 CRK15990.1 - 0.05 11.3 0.7 0.059 11.1 0.7 1.0 1 0 0 1 1 1 0 Hereditary spastic paraplegia protein strumpellin NACHT PF05729.12 CRK15991.1 - 1.6e-11 44.4 0.0 2.8e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 NACHT domain PNP_UDP_1 PF01048.20 CRK15991.1 - 3.4e-10 39.6 0.1 5.9e-10 38.8 0.1 1.4 1 0 0 1 1 1 1 Phosphorylase superfamily AAA_16 PF13191.6 CRK15991.1 - 5e-06 27.0 0.1 1.3e-05 25.6 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CRK15991.1 - 0.00051 20.3 0.0 0.0013 19.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 CRK15991.1 - 0.0053 16.0 0.0 0.0098 15.1 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain ResIII PF04851.15 CRK15991.1 - 0.019 15.0 0.0 0.12 12.4 0.0 2.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.22 CRK15991.1 - 0.041 14.3 0.0 0.12 12.8 0.0 1.8 1 0 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 CRK15991.1 - 0.062 13.2 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 CRK15991.1 - 0.094 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 CRK15991.1 - 0.11 12.5 0.0 1.3 9.1 0.0 2.4 1 1 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 CRK15991.1 - 0.13 11.3 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 APS_kinase PF01583.20 CRK15991.1 - 0.14 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Thymidylate_kin PF02223.17 CRK15991.1 - 0.26 11.0 1.4 9 5.9 0.0 2.3 2 0 0 2 2 2 0 Thymidylate kinase DUF3723 PF12520.8 CRK15993.1 - 1.8e-107 360.2 0.0 4.6e-78 263.1 0.0 3.9 1 1 2 3 3 3 3 Protein of unknown function (DUF3723) 3-alpha PF03475.14 CRK15993.1 - 0.077 12.9 0.0 0.31 11.0 0.0 2.1 1 0 0 1 1 1 0 3-alpha domain Pkinase PF00069.25 CRK15994.1 - 1.7e-11 44.0 0.0 3.2e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK15994.1 - 8.1e-08 31.9 0.0 1.3e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3435 PF11917.8 CRK15995.1 - 5.5e-09 35.5 0.2 4.7e-08 32.4 0.0 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF3435) Zn_clus PF00172.18 CRK15999.1 - 8.7e-08 32.2 5.0 1.4e-07 31.5 5.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TMEM95 PF15203.6 CRK15999.1 - 0.029 14.0 0.7 0.057 13.1 0.7 1.5 1 0 0 1 1 1 0 TMEM95 family Glyco_hydro_18 PF00704.28 CRK16002.1 - 1.5e-54 185.9 0.1 1.7e-54 185.7 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_18 PF00704.28 CRK16003.1 - 4.4e-17 62.8 0.0 5e-17 62.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 G_glu_transpept PF01019.21 CRK16004.1 - 3.5e-160 534.2 0.0 4e-160 534.0 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase DUF3723 PF12520.8 CRK16006.1 - 1.3e-65 222.1 5.9 2.8e-54 184.7 0.2 3.0 1 1 2 3 3 3 3 Protein of unknown function (DUF3723) mono-CXXC PF15626.6 CRK16006.1 - 0.12 12.7 0.1 0.33 11.3 0.1 1.7 1 0 0 1 1 1 0 single CXXC unit Phage_TAC_7 PF10109.9 CRK16006.1 - 0.17 12.0 0.1 38 4.5 0.0 3.3 3 0 0 3 3 3 0 Phage tail assembly chaperone proteins, E, or 41 or 14 RVT_1 PF00078.27 CRK16008.1 - 6.3e-37 127.2 0.0 1.2e-36 126.4 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 CRK16008.1 - 0.061 14.0 0.1 0.23 12.2 0.1 1.9 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase Glyco_hydro_18 PF00704.28 CRK16009.1 - 5e-13 49.4 0.0 5.7e-13 49.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Cyt-b5 PF00173.28 CRK16010.1 - 8.7e-16 57.8 0.0 2.8e-15 56.2 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.24 CRK16010.1 - 8.2e-14 52.0 15.7 8.2e-14 52.0 15.7 1.8 2 0 0 2 2 2 1 Fatty acid desaturase DUF4413 PF14372.6 CRK16010.1 - 0.1 12.9 0.2 0.23 11.8 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) APH PF01636.23 CRK16011.1 - 7.1e-18 65.4 0.4 1.1e-17 64.8 0.4 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 CRK16011.1 - 3.5e-05 23.3 0.0 0.0034 16.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CRK16011.1 - 0.0016 17.8 0.0 0.0049 16.2 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 CRK16011.1 - 0.0019 17.8 0.0 0.0037 16.9 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 CRK16011.1 - 0.036 13.7 0.0 0.48 10.0 0.0 2.1 2 0 0 2 2 2 0 RIO1 family PNP_UDP_1 PF01048.20 CRK16012.1 - 4.2e-14 52.4 0.0 1.2e-13 50.8 0.0 1.8 1 1 1 2 2 2 1 Phosphorylase superfamily AAA_30 PF13604.6 CRK16012.1 - 0.0017 18.1 0.0 0.0033 17.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 CRK16012.1 - 0.015 15.3 0.1 0.034 14.1 0.1 1.5 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 CRK16012.1 - 0.099 13.2 0.0 0.22 12.0 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 CRK16012.1 - 0.1 12.8 0.1 0.34 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain HET PF06985.11 CRK16013.1 - 1e-24 87.6 0.0 2.2e-24 86.5 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Fungal_trans PF04082.18 CRK16013.1 - 6.7e-07 28.6 0.1 1.5e-06 27.4 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain HpcH_HpaI PF03328.14 CRK16014.1 - 1.8e-27 96.0 0.0 2.5e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP-utilizers_C PF02896.18 CRK16014.1 - 0.0054 15.9 0.3 0.046 12.8 0.3 2.4 3 0 0 3 3 3 1 PEP-utilising enzyme, TIM barrel domain PK PF00224.21 CRK16014.1 - 0.016 14.1 1.3 0.027 13.4 0.9 1.4 1 1 1 2 2 2 0 Pyruvate kinase, barrel domain adh_short PF00106.25 CRK16015.1 - 2.5e-39 134.8 0.0 2.9e-39 134.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK16015.1 - 2.5e-34 118.9 0.0 3.1e-34 118.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK16015.1 - 2.1e-09 37.5 0.2 2.7e-09 37.2 0.2 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 CRK16015.1 - 0.043 13.6 0.1 0.11 12.3 0.1 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ERG4_ERG24 PF01222.17 CRK16016.1 - 1.7e-134 448.9 17.4 1.9e-134 448.7 17.4 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family PAP2_C PF14360.6 CRK16016.1 - 0.56 10.8 0.1 0.56 10.8 0.1 3.6 4 1 0 4 4 4 0 PAP2 superfamily C-terminal Fcf1 PF04900.12 CRK16018.1 - 1.4e-33 115.2 0.3 2.7e-33 114.3 0.3 1.4 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 CRK16018.1 - 1.5e-10 41.4 0.1 9.8e-10 38.8 0.0 2.0 2 0 0 2 2 2 1 PIN like domain DPPIV_N PF00930.21 CRK16020.1 - 4.2e-52 177.1 0.0 5.2e-52 176.8 0.0 1.1 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region ESX-1_EspG PF14011.6 CRK16020.1 - 0.00012 21.8 0.1 0.0002 21.0 0.1 1.3 1 0 0 1 1 1 1 EspG family IGPS PF00218.21 CRK16023.1 - 3.7e-78 262.2 0.0 4.1e-78 262.1 0.0 1.0 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase Adaptin_N PF01602.20 CRK16056.1 - 1.7e-104 350.3 0.0 2e-104 350.1 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region RTA1 PF04479.13 CRK16056.1 - 9.3e-56 188.7 5.8 1.5e-55 188.0 5.8 1.3 1 0 0 1 1 1 1 RTA1 like protein Cnd1 PF12717.7 CRK16056.1 - 6.2e-15 55.6 0.8 5.3e-14 52.6 0.1 2.8 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CRK16056.1 - 2.4e-09 37.4 13.6 2.1e-05 24.8 0.9 5.3 4 2 2 6 6 6 4 HEAT repeats HEAT PF02985.22 CRK16056.1 - 3.4e-08 33.1 4.0 0.033 14.4 0.0 5.9 6 0 0 6 6 6 2 HEAT repeat Cohesin_HEAT PF12765.7 CRK16056.1 - 6.3e-05 23.2 0.5 0.059 13.7 0.0 2.8 2 0 0 2 2 2 2 HEAT repeat associated with sister chromatid cohesion Cnd3 PF12719.7 CRK16056.1 - 0.06 12.5 0.3 0.27 10.4 0.1 2.0 2 0 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain RTP1_C1 PF10363.9 CRK16056.1 - 0.13 12.4 0.3 3.6 7.8 0.0 3.2 3 1 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 CRK16056.1 - 0.24 12.0 14.9 0.16 12.5 1.8 5.1 5 1 1 6 6 6 0 HEAT-like repeat MMR_HSR1 PF01926.23 CRK16070.1 - 3.3e-06 27.2 0.0 4.7e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase BetaGal_dom3 PF13363.6 CRK16070.1 - 0.02 14.5 0.0 0.034 13.7 0.0 1.3 1 0 0 1 1 1 0 Beta-galactosidase, domain 3 DUF3347 PF11827.8 CRK16072.1 - 0.95 9.6 4.8 0.32 11.2 1.5 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF3347) Peptidase_M28 PF04389.17 CRK16090.1 - 1.1e-34 119.9 0.0 1.3e-34 119.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 CRK16090.1 - 8.7e-06 25.6 0.0 1.4e-05 24.9 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 CRK16090.1 - 0.017 14.1 0.0 0.042 12.9 0.0 1.5 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase Actin PF00022.19 CRK16109.1 - 8.6e-90 301.3 0.0 4.6e-89 298.9 0.0 1.8 1 1 0 1 1 1 1 Actin DIE2_ALG10 PF04922.12 CRK16125.1 - 5.7e-57 193.8 0.4 3.9e-56 191.0 0.4 2.0 1 1 0 1 1 1 1 DIE2/ALG10 family Rrn6 PF10214.9 CRK16127.1 - 0.19 10.2 7.0 0.23 9.9 7.0 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Rtf2 PF04641.12 CRK16127.1 - 1.2 8.4 6.8 1.4 8.3 6.8 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger Radial_spoke_3 PF06098.11 CRK16127.1 - 1.7 7.8 13.0 2.2 7.5 13.0 1.1 1 0 0 1 1 1 0 Radial spoke protein 3 EMP70 PF02990.16 CRK16129.1 - 1.1e-202 674.3 3.4 1.6e-202 673.8 3.4 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 PIRT PF15099.6 CRK16129.1 - 6.2 6.4 7.9 1.3 8.6 3.3 2.2 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family Sas10_Utp3 PF04000.15 CRK16130.1 - 2.3e-16 60.2 0.6 2.3e-16 60.2 0.6 2.0 2 0 0 2 2 1 1 Sas10/Utp3/C1D family Pyr_redox_3 PF13738.6 CRK16130.1 - 9.4e-16 57.9 0.0 7.5e-15 55.0 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 CRK16130.1 - 7.8e-15 54.3 0.0 2.7e-14 52.5 0.0 1.8 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 CRK16130.1 - 2.2e-12 46.8 0.0 5.3e-10 39.0 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CRK16130.1 - 5.5e-10 38.9 0.1 4.3e-08 32.7 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 CRK16130.1 - 5.6e-06 26.5 0.5 2.3e-05 24.5 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 CRK16130.1 - 9.5e-05 22.9 2.0 0.24 12.0 0.0 3.0 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 CRK16130.1 - 0.00059 19.2 1.1 0.088 12.1 0.1 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 CRK16130.1 - 0.0035 17.0 7.7 0.0068 16.0 5.2 2.7 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 CRK16130.1 - 0.012 15.0 0.1 0.054 12.8 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 CRK16130.1 - 0.013 15.4 0.2 0.036 13.9 0.2 1.8 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 CRK16130.1 - 0.016 15.2 0.5 0.3 11.0 0.1 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding Shikimate_DH PF01488.20 CRK16130.1 - 0.04 14.0 0.0 13 5.9 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 CRK16130.1 - 0.12 11.4 4.8 0.023 13.8 1.1 1.7 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 CRK16130.1 - 0.14 10.8 2.0 0.49 9.0 0.4 2.3 2 0 0 2 2 2 0 HI0933-like protein RXT2_N PF08595.11 CRK16130.1 - 0.23 11.5 4.6 0.58 10.2 4.6 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal DNA_pol_phi PF04931.13 CRK16130.1 - 0.56 8.2 10.2 0.86 7.6 10.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi FAM176 PF14851.6 CRK16130.1 - 0.65 9.6 5.1 1.7 8.3 5.1 1.7 1 0 0 1 1 1 0 FAM176 family GIDA PF01134.22 CRK16130.1 - 1.2 8.2 3.3 0.95 8.5 0.7 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A PPP4R2 PF09184.11 CRK16130.1 - 3.1 7.3 9.9 0.35 10.4 4.6 1.9 2 0 0 2 2 2 0 PPP4R2 CDC45 PF02724.14 CRK16130.1 - 6.3 5.0 10.1 9.2 4.4 10.1 1.3 1 0 0 1 1 1 0 CDC45-like protein CENP-B_dimeris PF09026.10 CRK16130.1 - 8.6 6.8 12.5 22 5.5 12.5 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain p450 PF00067.22 CRK16132.1 - 1.8e-92 310.5 0.0 2.1e-92 310.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 VARLMGL PF14383.6 CRK16132.1 - 0.13 11.8 0.1 0.13 11.8 0.1 2.0 2 0 0 2 2 2 0 DUF761-associated sequence motif TPR_2 PF07719.17 CRK16136.1 - 3.9e-10 39.1 8.0 0.012 15.7 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 CRK16136.1 - 2.5e-09 36.5 4.1 0.0047 16.7 0.1 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat STI1 PF17830.1 CRK16136.1 - 1.4e-06 28.2 33.7 0.0018 18.2 8.8 3.9 4 0 0 4 4 4 2 STI1 domain TPR_8 PF13181.6 CRK16136.1 - 4.5e-06 26.5 2.6 0.089 13.1 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 CRK16136.1 - 8.9e-06 25.3 5.2 0.011 15.4 0.4 3.1 2 1 1 3 3 3 3 TPR repeat TPR_17 PF13431.6 CRK16136.1 - 5.4e-05 23.3 1.9 0.0058 16.9 0.3 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 CRK16136.1 - 0.00017 22.1 10.4 0.29 12.1 0.4 3.5 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 CRK16136.1 - 0.00098 19.0 1.0 0.71 10.0 0.0 2.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 CRK16136.1 - 0.0018 18.9 15.1 0.18 12.5 11.4 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 CRK16136.1 - 0.0062 17.0 6.7 0.081 13.4 0.5 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat XPC-binding PF09280.11 CRK16136.1 - 0.0064 16.2 14.8 0.25 11.1 2.8 2.8 3 0 0 3 3 3 2 XPC-binding domain TPR_9 PF13371.6 CRK16136.1 - 0.015 15.4 2.5 0.036 14.2 2.5 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 CRK16136.1 - 0.022 15.0 9.3 0.078 13.3 4.7 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat GerD PF17898.1 CRK16136.1 - 0.039 13.9 9.3 1.8 8.6 0.9 3.1 3 0 0 3 3 3 0 Spore germination GerD central core domain TPR_6 PF13174.6 CRK16136.1 - 0.051 14.2 2.0 0.26 12.0 0.5 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 CRK16136.1 - 0.21 11.7 1.7 5.3 7.2 0.1 3.0 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 CRK16136.1 - 2.3 8.2 8.2 1.6 8.7 2.3 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.25 CRK16138.1 - 7.8e-06 25.4 0.0 1.3e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pectinesterase PF01095.19 CRK16139.1 - 2e-42 145.0 0.7 2.7e-42 144.5 0.7 1.0 1 0 0 1 1 1 1 Pectinesterase AA_permease PF00324.21 CRK16141.1 - 5.2e-122 407.8 32.8 6.3e-122 407.6 32.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CRK16141.1 - 1.4e-27 96.6 38.4 1.7e-27 96.3 38.4 1.1 1 0 0 1 1 1 1 Amino acid permease MARVEL PF01284.23 CRK16145.1 - 1.6e-06 28.2 9.7 2.1e-06 27.8 9.7 1.2 1 0 0 1 1 1 1 Membrane-associating domain Tmemb_40 PF10160.9 CRK16145.1 - 0.01 15.3 0.4 0.01 15.3 0.4 1.7 1 1 1 2 2 2 0 Predicted membrane protein GSG-1 PF07803.11 CRK16145.1 - 0.033 14.1 0.1 0.033 14.1 0.1 2.2 3 0 0 3 3 3 0 GSG1-like protein Herpes_gE PF02480.16 CRK16145.1 - 0.14 10.9 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF4231 PF14015.6 CRK16145.1 - 1.3 9.5 6.3 1.3 9.5 2.4 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF4231) DUF4191 PF13829.6 CRK16145.1 - 3.6 6.9 7.7 22 4.3 0.0 2.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4191) Glyco_transf_28 PF03033.20 CRK16147.1 - 2.1e-22 79.7 0.0 5.5e-21 75.1 0.0 2.5 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 CRK16147.1 - 0.0088 14.9 0.1 0.018 13.8 0.1 1.5 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.11 CRK16147.1 - 0.05 14.0 6.4 0.23 11.9 0.2 3.4 3 1 0 3 3 3 0 Autophagy-related protein C terminal domain Glyco_tran_28_C PF04101.16 CRK16147.1 - 0.14 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain PAM2 PF07145.15 CRK16152.1 - 7e-05 22.2 0.0 0.00017 21.1 0.0 1.6 1 0 0 1 1 1 1 Ataxin-2 C-terminal region STI1 PF17830.1 CRK16152.1 - 0.0011 18.8 7.7 0.0011 18.8 7.7 2.5 2 0 0 2 2 2 1 STI1 domain XPC-binding PF09280.11 CRK16152.1 - 0.36 10.6 4.3 0.32 10.7 2.8 1.7 2 0 0 2 2 2 0 XPC-binding domain Pectinesterase PF01095.19 CRK16154.1 - 4.6e-42 143.8 0.4 7e-42 143.2 0.4 1.1 1 0 0 1 1 1 1 Pectinesterase Pkinase PF00069.25 CRK16154.1 - 2.7e-05 23.7 0.0 4.3e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain AA_permease PF00324.21 CRK16156.1 - 3.3e-116 388.7 32.4 4e-116 388.4 32.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CRK16156.1 - 3.6e-26 92.0 37.8 4.3e-26 91.7 37.8 1.1 1 0 0 1 1 1 1 Amino acid permease MARVEL PF01284.23 CRK16158.1 - 4.1e-07 30.1 10.4 5.2e-07 29.8 10.4 1.1 1 0 0 1 1 1 1 Membrane-associating domain GSG-1 PF07803.11 CRK16158.1 - 0.01 15.7 0.1 0.01 15.7 0.1 2.2 3 0 0 3 3 3 0 GSG1-like protein TssN PF17555.2 CRK16158.1 - 0.12 11.7 1.6 0.16 11.3 1.6 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssN DUF4231 PF14015.6 CRK16158.1 - 0.45 11.0 6.9 0.32 11.5 2.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF4231) DUF4064 PF13273.6 CRK16158.1 - 4.5 7.6 8.9 8.8 6.7 0.2 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) Glyco_transf_28 PF03033.20 CRK16160.1 - 8.7e-25 87.4 0.0 4.8e-23 81.7 0.0 2.6 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain ATG_C PF09333.11 CRK16160.1 - 0.00032 21.0 20.0 0.3 11.5 0.2 5.4 5 1 0 5 5 5 2 Autophagy-related protein C terminal domain VPS13_C PF16909.5 CRK16160.1 - 0.0043 16.9 1.0 6.2 6.6 0.0 3.3 4 0 0 4 4 4 2 Vacuolar-sorting-associated 13 protein C-terminal UDPGT PF00201.18 CRK16160.1 - 0.0074 15.1 0.1 0.015 14.1 0.1 1.4 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase RCSD PF05177.12 CRK16160.1 - 0.3 12.0 2.9 23 6.0 0.2 2.3 2 0 0 2 2 2 0 RCSD region NST1 PF13945.6 CRK16162.1 - 7.4e-54 182.8 11.5 7.4e-54 182.8 11.5 6.5 3 3 3 6 6 6 1 Salt tolerance down-regulator Ras PF00071.22 CRK16164.1 - 6.3e-50 168.9 0.0 7.5e-50 168.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CRK16164.1 - 1.4e-22 80.2 0.0 1.8e-22 79.8 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CRK16164.1 - 3.2e-06 26.7 0.0 4.7e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CRK16164.1 - 0.009 15.4 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 CRK16164.1 - 0.025 14.0 0.0 0.031 13.7 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CRK16164.1 - 0.076 13.1 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase PduV-EutP PF10662.9 CRK16164.1 - 0.12 12.1 0.0 2.4 7.9 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_21 PF13304.6 CRK16164.1 - 0.22 11.3 0.0 0.35 10.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system MRP-L28 PF09812.9 CRK16166.1 - 3e-05 24.2 0.1 3.7e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 DNA_pol_B_thumb PF14791.6 CRK16166.1 - 0.031 14.4 0.1 0.05 13.8 0.1 1.5 1 0 0 1 1 1 0 DNA polymerase beta thumb Bacteriocin_II PF01721.18 CRK16168.1 - 0.13 12.4 0.1 0.25 11.5 0.1 1.4 1 0 0 1 1 1 0 Class II bacteriocin DUF3632 PF12311.8 CRK16170.1 - 2.3e-30 106.3 0.0 2.9e-30 106.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) TPP_enzyme_N PF02776.18 CRK16172.1 - 4.4e-50 169.7 0.0 2.2e-49 167.4 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 CRK16172.1 - 1.6e-38 131.6 1.0 4.3e-38 130.2 0.5 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 CRK16172.1 - 0.00033 20.5 0.0 0.013 15.3 0.0 2.8 3 1 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CO_dh PF02552.16 CRK16172.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit Sugar_tr PF00083.24 CRK16179.1 - 1.8e-34 119.4 10.1 2.1e-34 119.2 10.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter APH PF01636.23 CRK16182.1 - 3.2e-06 27.2 0.3 3.2e-06 27.2 0.3 1.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family Bac_luciferase PF00296.20 CRK16184.1 - 7.2e-58 196.5 3.8 1e-57 195.9 3.8 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase MFS_1 PF07690.16 CRK16184.1 - 3.1e-08 33.0 36.0 5.5e-08 32.1 36.0 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 CRK16184.1 - 4.9e-05 23.1 4.9 4.9e-05 23.1 4.9 2.1 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 FMO-like PF00743.19 CRK16188.1 - 2.9e-17 62.3 0.0 1.8e-16 59.7 0.0 2.1 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 CRK16188.1 - 5.5e-10 39.3 0.0 6e-09 36.0 0.0 2.6 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CRK16188.1 - 1.8e-09 37.2 0.0 7.2e-07 28.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CRK16188.1 - 9.2e-07 28.4 0.0 1.5e-05 24.4 0.0 2.8 3 1 1 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CRK16188.1 - 4.7e-05 23.4 0.0 0.41 10.6 0.0 3.4 3 0 0 3 3 3 2 FAD-NAD(P)-binding K_oxygenase PF13434.6 CRK16188.1 - 8.1e-05 21.9 0.0 0.004 16.3 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 CRK16188.1 - 0.0025 17.5 0.1 1.3 8.5 0.1 2.6 2 1 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 CRK16188.1 - 0.009 15.3 0.1 0.029 13.6 0.0 1.9 2 0 0 2 2 2 1 Thi4 family Bac_luciferase PF00296.20 CRK16189.1 - 1.2e-56 192.5 0.0 1.7e-56 191.9 0.0 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase MFS_1 PF07690.16 CRK16189.1 - 6.3e-17 61.5 18.8 1.4e-14 53.8 12.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily ECH_1 PF00378.20 CRK16190.1 - 1.5e-17 63.8 0.0 2e-17 63.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CRK16190.1 - 2.5e-07 30.5 0.0 3.4e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 CRK16190.1 - 0.011 15.6 0.0 0.97 9.4 0.0 2.3 2 0 0 2 2 2 0 Peptidase family S49 FAD_binding_3 PF01494.19 CRK16191.1 - 4.3e-14 52.5 4.1 1.1e-12 47.9 2.1 2.7 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 CRK16191.1 - 0.0003 21.0 0.3 0.0017 18.6 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain UCH PF00443.29 CRK16192.1 - 4.9e-36 124.5 0.0 2.3e-32 112.5 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CRK16192.1 - 3.3e-05 23.6 8.2 0.00067 19.3 8.2 2.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Oxysterol_BP PF01237.18 CRK16193.1 - 8.9e-63 212.4 0.6 1.4e-60 205.1 0.6 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein Mac PF12464.8 CRK16194.1 - 1.1e-11 44.7 0.0 1.7e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.24 CRK16194.1 - 3.4e-10 39.2 7.7 1.6e-05 24.4 0.3 4.1 3 1 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 CRK16194.1 - 9e-09 34.9 6.9 6.5e-05 22.6 0.4 3.4 3 1 1 4 4 4 3 Hexapeptide repeat of succinyl-transferase Ac110_PIF PF07280.11 CRK16194.1 - 0.12 12.2 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Per os infectivity factor AC110 DHC_N1 PF08385.12 CRK16195.1 - 5.3e-73 246.5 0.7 6.6e-73 246.2 0.7 1.1 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 DUF5063 PF16702.5 CRK16195.1 - 0.011 16.1 0.2 4.5 7.6 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF5063) RRM_1 PF00076.22 CRK16196.1 - 1.9e-28 98.1 0.0 3.8e-16 58.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.25 CRK16196.1 - 4.2e-17 62.4 0.0 5.9e-17 61.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RRM_occluded PF16842.5 CRK16196.1 - 1.4e-05 24.8 0.0 0.0011 18.8 0.0 2.2 2 0 0 2 2 2 1 Occluded RNA-recognition motif Pkinase_Tyr PF07714.17 CRK16196.1 - 0.0011 18.4 0.0 0.0017 17.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Nup35_RRM_2 PF14605.6 CRK16196.1 - 0.0049 16.8 0.0 0.51 10.4 0.0 2.4 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 CRK16196.1 - 0.021 14.4 0.0 4 7.0 0.0 2.5 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Acetyltransf_10 PF13673.7 CRK16196.1 - 0.061 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain TMEM51 PF15345.6 CRK16199.1 - 0.46 10.3 4.1 0.86 9.4 4.1 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 AAA PF00004.29 CRK16212.1 - 1.2e-43 148.7 0.0 2.6e-43 147.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CRK16212.1 - 3.5e-11 42.7 0.1 6.4e-11 41.9 0.1 1.4 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 CRK16212.1 - 4.4e-08 33.7 0.8 4.2e-06 27.2 0.8 3.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 CRK16212.1 - 2.6e-06 27.5 0.1 1.5e-05 25.0 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 CRK16212.1 - 1.4e-05 24.5 0.0 2.7e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 CRK16212.1 - 3.5e-05 24.1 0.4 0.0097 16.2 0.1 2.7 2 1 0 3 3 2 1 AAA domain RuvB_N PF05496.12 CRK16212.1 - 0.00015 21.5 0.0 0.00036 20.3 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 CRK16212.1 - 0.00069 19.8 0.0 0.0022 18.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 CRK16212.1 - 0.0014 18.8 0.0 0.003 17.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 CRK16212.1 - 0.0024 17.6 0.0 0.0053 16.5 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.6 CRK16212.1 - 0.0035 16.9 0.6 0.18 11.3 0.2 2.4 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.21 CRK16212.1 - 0.0057 16.1 0.4 0.015 14.7 0.4 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 CRK16212.1 - 0.01 16.4 0.0 0.026 15.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 CRK16212.1 - 0.017 15.4 0.1 0.059 13.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 CRK16212.1 - 0.026 14.5 0.0 0.4 10.5 0.0 2.2 1 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 CRK16212.1 - 0.029 13.9 0.1 0.15 11.6 0.1 2.1 1 1 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 CRK16212.1 - 0.032 14.2 0.3 0.7 9.8 0.1 2.2 2 0 0 2 2 2 0 NACHT domain AAA_14 PF13173.6 CRK16212.1 - 0.037 14.1 0.0 0.072 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 CRK16212.1 - 0.038 13.3 0.0 0.085 12.1 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.6 CRK16212.1 - 0.038 14.4 0.0 0.082 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 CRK16212.1 - 0.047 13.7 0.0 0.094 12.7 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 CRK16212.1 - 0.055 13.2 0.2 0.18 11.5 0.1 2.2 2 1 0 2 2 1 0 AAA domain ATPase PF06745.13 CRK16212.1 - 0.075 12.4 0.2 0.38 10.1 0.1 2.0 1 1 0 2 2 2 0 KaiC Cytochrom_C550 PF14495.6 CRK16212.1 - 0.091 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Cytochrome c-550 domain PhoH PF02562.16 CRK16212.1 - 0.099 12.1 0.2 0.22 11.0 0.2 1.5 1 0 0 1 1 1 0 PhoH-like protein ABC_tran PF00005.27 CRK16212.1 - 0.18 12.3 0.3 0.93 10.0 0.1 2.1 2 1 0 2 2 2 0 ABC transporter Glyco_transf_54 PF04666.13 CRK16212.1 - 0.21 10.4 0.0 0.33 9.8 0.0 1.2 1 0 0 1 1 1 0 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region BCDHK_Adom3 PF10436.9 CRK16230.1 - 1.7e-32 112.5 0.0 2.3e-32 112.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 CRK16230.1 - 3.8e-05 24.1 0.0 9.1e-05 22.9 0.0 1.6 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Raffinose_syn PF05691.12 CRK16237.1 - 0.16 9.7 0.1 0.22 9.3 0.1 1.1 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 Hist_deacetyl PF00850.19 CRK16238.1 - 3.9e-14 52.9 0.1 4.4e-14 52.7 0.1 1.0 1 0 0 1 1 1 1 Histone deacetylase domain PFOR_II PF17147.4 CRK16239.1 - 6.2e-08 32.9 1.5 2.5e-07 31.0 0.4 2.2 2 0 0 2 2 2 1 Pyruvate:ferredoxin oxidoreductase core domain II Transketolase_C PF02780.20 CRK16239.1 - 0.0027 17.6 0.0 0.0054 16.6 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain DUF5610 PF18433.1 CRK16239.1 - 0.01 16.3 0.5 0.023 15.2 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5610) 2OG-FeII_Oxy_4 PF13661.6 CRK16241.1 - 2.1e-26 92.4 0.0 8.1e-26 90.5 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 CRK16241.1 - 9.8e-15 55.2 0.0 1.8e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ofd1_CTDD PF10637.9 CRK16241.1 - 6.6e-06 25.7 0.0 0.074 12.4 0.0 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term zf-HC5HC2H_2 PF13832.6 CRK16242.1 - 8.4e-15 54.9 0.5 8.4e-15 54.9 0.5 2.4 2 1 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 CRK16242.1 - 5.9e-10 39.3 1.8 5.9e-10 39.3 1.8 2.7 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.6 CRK16242.1 - 2.8e-06 26.8 0.5 2.8e-06 26.8 0.5 3.9 4 1 1 5 5 5 1 PHD-finger PHD PF00628.29 CRK16242.1 - 0.0064 16.4 0.5 0.0064 16.4 0.5 4.1 3 1 1 4 4 4 1 PHD-finger DUF2663 PF10864.8 CRK16242.1 - 0.13 12.7 1.5 0.17 12.3 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2663) DUF2681 PF10883.8 CRK16242.1 - 0.21 12.0 2.4 0.3 11.5 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) PNISR PF15996.5 CRK16242.1 - 0.44 10.8 6.5 0.61 10.3 6.5 1.1 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR CTU2 PF10288.9 CRK16242.1 - 0.86 9.9 8.4 2.2 8.6 8.5 1.8 1 1 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 Per1 PF04080.13 CRK16243.1 - 1e-62 212.2 5.4 1.1e-62 212.1 5.4 1.0 1 0 0 1 1 1 1 Per1-like family Lum_binding PF00677.17 CRK16244.1 - 2.5e-42 142.7 0.2 6.7e-21 74.1 0.0 2.1 2 0 0 2 2 2 2 Lumazine binding domain ERCC4 PF02732.15 CRK16246.1 - 1e-22 81.0 0.1 1.5e-22 80.5 0.1 1.3 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.6 CRK16246.1 - 0.0079 16.6 0.0 0.026 14.9 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain DUF4373 PF14297.6 CRK16246.1 - 0.2 12.5 0.3 0.61 10.9 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4373) Lyase_1 PF00206.20 CRK16247.1 - 5.6e-12 45.7 0.0 1e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Lyase Zn_clus PF00172.18 CRK16247.1 - 4.9e-09 36.2 10.0 8e-09 35.5 10.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 CRK16248.1 - 1.9e-10 40.2 40.4 1.6e-05 24.1 24.2 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily DUF5423 PF17461.2 CRK16248.1 - 6.1 5.6 6.2 12 4.6 6.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5423) Fungal_trans PF04082.18 CRK16251.1 - 9.9e-22 77.2 0.5 1.6e-21 76.6 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 CRK16251.1 - 1.2e-08 34.9 13.4 0.00019 21.7 2.0 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CRK16251.1 - 1.2e-06 28.6 12.9 2.3e-06 27.8 7.1 2.8 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 CRK16251.1 - 0.00048 20.7 13.0 0.037 14.9 2.1 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger C1_4 PF07975.12 CRK16251.1 - 0.35 11.1 2.1 0.9 9.8 2.1 1.7 1 0 0 1 1 1 0 TFIIH C1-like domain zf-C2H2_jaz PF12171.8 CRK16251.1 - 0.83 10.0 3.7 0.43 10.9 0.4 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CRK16251.1 - 2.5 8.6 5.2 0.63 10.5 1.1 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 CRK16252.1 - 2.3e-11 43.5 44.1 1.6e-05 25.1 0.8 7.2 7 0 0 7 7 7 3 Zinc finger, C2H2 type NACHT PF05729.12 CRK16252.1 - 2.4e-09 37.4 0.0 5.7e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain zf-C2H2_6 PF13912.6 CRK16252.1 - 5.2e-07 29.5 26.3 0.00056 19.8 0.3 5.2 5 0 0 5 5 5 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CRK16252.1 - 5.3e-07 29.8 0.4 5.3e-07 29.8 0.4 9.6 11 0 0 11 11 9 4 Zinc-finger double domain AAA_22 PF13401.6 CRK16252.1 - 7.1e-06 26.3 0.0 0.0048 17.2 0.0 3.5 3 0 0 3 3 3 1 AAA domain zf-met PF12874.7 CRK16252.1 - 2.2e-05 24.7 12.8 0.034 14.5 0.5 4.1 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 CRK16252.1 - 5.1e-05 23.8 5.6 0.004 17.9 0.5 8.1 8 0 0 8 8 7 3 C2H2-type zinc finger AAA_16 PF13191.6 CRK16252.1 - 0.00015 22.2 0.0 0.00091 19.6 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain zf-C2HE PF16278.5 CRK16252.1 - 0.00016 22.0 9.0 0.31 11.5 0.1 3.8 2 1 1 3 3 3 2 C2HE / C2H2 / C2HC zinc-binding finger ROS_MUCR PF05443.11 CRK16252.1 - 0.00057 19.9 0.0 1.6 8.8 0.0 2.4 2 0 0 2 2 2 2 ROS/MUCR transcriptional regulator protein NB-ARC PF00931.22 CRK16252.1 - 0.00083 18.6 0.0 0.0025 17.0 0.0 1.8 1 1 0 1 1 1 1 NB-ARC domain SbcCD_C PF13558.6 CRK16252.1 - 0.0012 19.1 0.0 5.5 7.3 0.0 3.5 4 0 0 4 4 3 2 Putative exonuclease SbcCD, C subunit DUF1936 PF09151.10 CRK16252.1 - 0.0019 18.1 3.8 1.2 9.1 0.3 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF1936) zf-C2H2_jaz PF12171.8 CRK16252.1 - 0.0041 17.4 8.6 0.85 10.0 0.3 3.8 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding RNA_helicase PF00910.22 CRK16252.1 - 0.0057 17.0 0.1 0.77 10.2 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA PF00004.29 CRK16252.1 - 0.0099 16.3 0.0 0.029 14.8 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.14 CRK16252.1 - 0.061 12.5 0.0 0.2 10.8 0.0 1.6 1 1 0 2 2 2 0 KAP family P-loop domain Zn-ribbon_8 PF09723.10 CRK16252.1 - 0.094 12.8 1.2 1.6 8.9 0.1 3.1 2 1 1 3 3 3 0 Zinc ribbon domain zf-C2H2_2 PF12756.7 CRK16252.1 - 0.12 12.7 5.3 18 5.7 0.0 3.8 3 1 1 4 4 3 0 C2H2 type zinc-finger (2 copies) AAA_24 PF13479.6 CRK16252.1 - 0.16 11.6 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain zf-C2H2_3rep PF18868.1 CRK16252.1 - 2.9 8.6 9.8 0.53 11.0 2.1 3.2 2 1 2 4 4 4 0 Zinc finger C2H2-type, 3 repeats LIM PF00412.22 CRK16252.1 - 4.7 7.5 5.8 11 6.3 2.5 3.0 2 0 0 2 2 2 0 LIM domain HIRAN PF08797.11 CRK16253.1 - 0.08 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 HIRAN domain X PF00739.19 CRK16253.1 - 0.44 10.7 4.2 0.6 10.2 1.7 2.4 3 0 0 3 3 3 0 Trans-activation protein X HIRAN PF08797.11 CRK16254.1 - 0.026 14.4 0.0 0.052 13.5 0.0 1.5 1 0 0 1 1 1 0 HIRAN domain X PF00739.19 CRK16254.1 - 1.4 9.1 6.1 0.41 10.8 1.8 2.3 3 0 0 3 3 3 0 Trans-activation protein X SnoaL_4 PF13577.6 CRK16256.1 - 2.4e-07 30.9 0.1 6.9e-07 29.4 0.0 1.8 2 0 0 2 2 2 1 SnoaL-like domain Asp PF00026.23 CRK16257.1 - 1.4e-51 175.8 0.0 1.9e-51 175.4 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Cellulase PF00150.18 CRK16257.1 - 1.4e-17 64.1 0.4 2e-17 63.5 0.4 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) TAXi_N PF14543.6 CRK16257.1 - 3.3e-11 43.7 0.4 3.3e-09 37.2 0.5 3.1 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Glyco_hydro_42 PF02449.15 CRK16257.1 - 0.0071 15.7 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Beta-galactosidase Glyco_hydro_2_C PF02836.17 CRK16257.1 - 0.13 11.3 0.0 1.5 7.9 0.0 2.3 2 1 0 2 2 2 0 Glycosyl hydrolases family 2, TIM barrel domain zf-C3HC4_4 PF15227.6 CRK16258.1 - 2.9 8.1 12.4 0.19 11.9 2.9 2.9 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING SnoaL_4 PF13577.6 CRK16259.1 - 1.4e-07 31.7 0.0 3.7e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 SnoaL-like domain Asp PF00026.23 CRK16260.1 - 1e-51 176.2 0.0 1.5e-51 175.7 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Cellulase PF00150.18 CRK16260.1 - 1.1e-17 64.4 0.2 1.7e-17 63.8 0.2 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) TAXi_N PF14543.6 CRK16260.1 - 1.1e-11 45.3 0.3 1.5e-09 38.4 0.2 3.1 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Glyco_hydro_42 PF02449.15 CRK16260.1 - 0.0052 16.2 0.0 0.01 15.2 0.0 1.4 2 0 0 2 2 2 1 Beta-galactosidase Glyco_hydro_2_C PF02836.17 CRK16260.1 - 0.051 12.7 0.0 0.59 9.2 0.0 2.3 2 1 0 2 2 2 0 Glycosyl hydrolases family 2, TIM barrel domain zf-C3HC4_4 PF15227.6 CRK16261.1 - 5 7.4 9.4 0.81 9.9 3.0 2.6 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING SARAF PF06682.12 CRK16262.1 - 0.0024 17.6 0.0 0.0026 17.5 0.0 1.0 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis DUF2615 PF11027.8 CRK16262.1 - 0.0026 17.9 0.2 0.0045 17.1 0.2 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2615) Sensor PF13796.6 CRK16262.1 - 0.004 17.2 1.3 0.0061 16.6 1.3 1.3 1 1 0 1 1 1 1 Putative sensor Cytochrom_B558a PF05038.13 CRK16262.1 - 0.0067 16.0 0.3 0.0096 15.5 0.3 1.3 1 0 0 1 1 1 1 Cytochrome Cytochrome b558 alpha-subunit Amnionless PF14828.6 CRK16262.1 - 0.0072 15.2 0.0 0.0081 15.0 0.0 1.0 1 0 0 1 1 1 1 Amnionless HemY_N PF07219.13 CRK16262.1 - 0.0092 16.2 0.1 0.012 15.8 0.1 1.2 1 0 0 1 1 1 1 HemY protein N-terminus DUF5305 PF17231.2 CRK16262.1 - 0.01 15.2 0.0 0.012 15.0 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5305) LPG_synthase_TM PF03706.13 CRK16262.1 - 0.017 14.7 0.0 0.019 14.5 0.0 1.0 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region Sigma_reg_N PF13800.6 CRK16262.1 - 0.024 14.9 0.0 0.035 14.4 0.0 1.2 1 0 0 1 1 1 0 Sigma factor regulator N-terminal SKG6 PF08693.10 CRK16262.1 - 0.038 13.4 0.4 0.038 13.4 0.4 1.9 2 0 0 2 2 1 0 Transmembrane alpha-helix domain Podoplanin PF05808.11 CRK16262.1 - 0.039 14.1 0.1 0.05 13.7 0.1 1.2 1 0 0 1 1 1 0 Podoplanin DUF4448 PF14610.6 CRK16262.1 - 0.1 12.3 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) EVC2_like PF12297.8 CRK16262.1 - 0.12 11.0 0.0 0.14 10.8 0.0 1.0 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein DUF4703 PF15775.5 CRK16262.1 - 0.13 12.1 4.5 0.14 12.0 4.3 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4703) Rrn6 PF10214.9 CRK16262.1 - 0.15 10.6 0.0 0.14 10.7 0.0 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor 7tm_1 PF00001.21 CRK16262.1 - 0.15 11.3 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF4834 PF16118.5 CRK16262.1 - 0.2 12.6 0.0 0.31 12.0 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) Vpu PF00558.19 CRK16262.1 - 0.24 11.2 0.0 0.3 10.9 0.0 1.1 1 0 0 1 1 1 0 Vpu protein CAP_N PF01213.19 CRK16262.1 - 0.39 10.2 11.5 0.44 10.0 11.5 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Adeno_E3_CR2 PF02439.15 CRK16262.1 - 0.57 10.0 17.1 3.6 7.4 17.1 2.0 1 1 0 1 1 1 0 Adenovirus E3 region protein CR2 Mito_fiss_reg PF05308.11 CRK16262.1 - 1.2 9.2 6.1 1.8 8.6 6.1 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator TT_ORF1 PF02956.14 CRK16262.1 - 2 7.0 3.4 1.8 7.1 3.4 1.1 1 0 0 1 1 1 0 TT viral orf 1 DUF755 PF05501.11 CRK16262.1 - 3.7 7.8 7.2 3.7 7.8 6.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Transgly_assoc PF04226.13 CRK16264.1 - 0.021 15.1 0.2 0.027 14.7 0.2 1.1 1 0 0 1 1 1 0 Transglycosylase associated protein Cupin_2 PF07883.11 CRK16265.1 - 1.3e-19 69.7 2.0 6.4e-16 57.8 0.2 3.2 3 0 0 3 3 3 2 Cupin domain SesA PF17107.5 CRK16265.1 - 0.0017 18.5 0.2 0.0031 17.7 0.2 1.4 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases FAA_hydrolase PF01557.18 CRK16266.1 - 2e-61 207.5 0.0 2.5e-61 207.1 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Imm-NTF2-2 PF15631.6 CRK16266.1 - 0.082 13.2 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 NTF2 fold immunity protein Fungal_trans PF04082.18 CRK16267.1 - 1.2e-22 80.2 0.0 1.9e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK16267.1 - 1.4e-05 25.1 9.1 2.9e-05 24.1 9.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Helicase_C PF00271.31 CRK16268.1 - 9.3e-16 58.2 0.0 1.8e-15 57.2 0.0 1.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 CRK16268.1 - 0.0015 17.8 0.2 0.002 17.4 0.2 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Sensor PF13796.6 CRK16269.1 - 0.0027 17.8 0.8 0.0062 16.6 0.0 1.8 2 0 0 2 2 2 1 Putative sensor Amnionless PF14828.6 CRK16269.1 - 0.0093 14.8 0.0 0.011 14.6 0.0 1.0 1 0 0 1 1 1 1 Amnionless DUF4703 PF15775.5 CRK16269.1 - 0.013 15.3 0.5 0.016 15.1 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4703) HemY_N PF07219.13 CRK16269.1 - 0.015 15.5 0.1 0.022 15.0 0.1 1.3 1 0 0 1 1 1 0 HemY protein N-terminus DUF5305 PF17231.2 CRK16269.1 - 0.016 14.6 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5305) LPG_synthase_TM PF03706.13 CRK16269.1 - 0.019 14.5 0.0 0.022 14.3 0.0 1.2 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region SARAF PF06682.12 CRK16269.1 - 0.025 14.2 0.0 0.029 14.0 0.0 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF2615 PF11027.8 CRK16269.1 - 0.025 14.7 0.0 0.042 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) Trp_oprn_chp PF09534.10 CRK16269.1 - 0.029 14.2 0.1 0.034 14.0 0.1 1.1 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Sigma_reg_N PF13800.6 CRK16269.1 - 0.04 14.2 0.0 0.062 13.6 0.0 1.2 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Cytochrom_B558a PF05038.13 CRK16269.1 - 0.044 13.4 0.1 0.056 13.0 0.1 1.2 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit Podoplanin PF05808.11 CRK16269.1 - 0.055 13.6 0.1 0.07 13.2 0.1 1.2 1 0 0 1 1 1 0 Podoplanin SKG6 PF08693.10 CRK16269.1 - 0.06 12.8 0.4 0.06 12.8 0.4 1.8 2 0 0 2 2 1 0 Transmembrane alpha-helix domain DUF4448 PF14610.6 CRK16269.1 - 0.13 12.0 0.0 0.16 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) EVC2_like PF12297.8 CRK16269.1 - 0.2 10.3 0.0 0.23 10.1 0.0 1.1 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein Adeno_E3_CR2 PF02439.15 CRK16269.1 - 0.47 10.3 15.9 2.5 7.9 15.9 2.0 1 1 0 1 1 1 0 Adenovirus E3 region protein CR2 CAP_N PF01213.19 CRK16269.1 - 9 5.7 6.6 11 5.4 6.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal FAA_hydrolase PF01557.18 CRK16272.1 - 5.3e-63 212.6 0.0 6.6e-63 212.3 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Imm-NTF2-2 PF15631.6 CRK16272.1 - 0.047 13.9 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 NTF2 fold immunity protein SNF2_N PF00176.23 CRK16273.1 - 1.6e-50 171.8 0.0 1.9e-48 165.0 0.0 2.2 1 1 0 2 2 2 1 SNF2 family N-terminal domain HIRAN PF08797.11 CRK16273.1 - 2.1e-23 82.0 0.0 5.8e-23 80.6 0.0 1.8 2 0 0 2 2 2 1 HIRAN domain Fungal_trans PF04082.18 CRK16273.1 - 1.1e-22 80.4 0.1 2.7e-22 79.1 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Helicase_C PF00271.31 CRK16273.1 - 1.2e-15 57.9 0.0 2.7e-15 56.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 CRK16273.1 - 9.2e-05 22.2 10.4 0.00021 21.1 10.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CRK16273.1 - 0.00036 20.8 9.9 0.00036 20.8 9.9 2.1 2 0 0 2 2 1 1 Ring finger domain Zn_clus PF00172.18 CRK16273.1 - 0.00064 19.8 12.6 0.00064 19.8 12.6 2.2 2 0 0 2 2 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C3HC4_2 PF13923.6 CRK16273.1 - 0.0035 17.2 10.4 0.0087 15.9 10.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CRK16273.1 - 0.02 14.9 7.5 0.042 13.9 7.5 1.6 1 0 0 1 1 1 0 RING-type zinc-finger UBA_4 PF14555.6 CRK16273.1 - 0.03 14.2 0.0 0.086 12.7 0.0 1.8 1 0 0 1 1 1 0 UBA-like domain ERCC3_RAD25_C PF16203.5 CRK16273.1 - 0.45 9.7 4.6 0.18 11.0 0.2 2.2 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase zf-C3HC4_4 PF15227.6 CRK16273.1 - 0.46 10.7 8.2 1.1 9.5 8.2 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING SQS_PSY PF00494.19 CRK16274.1 - 5.2e-55 186.8 1.5 6.6e-55 186.4 1.5 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase Ribosomal_S6 PF01250.17 CRK16275.1 - 3.7e-31 107.3 0.0 3.9e-16 59.1 0.0 3.1 3 0 0 3 3 3 2 Ribosomal protein S6 SQS_PSY PF00494.19 CRK16275.1 - 6.4e-15 55.4 0.1 1.4e-14 54.2 0.1 1.5 1 0 0 1 1 1 1 Squalene/phytoene synthase Cullin_binding PF03556.15 CRK16276.1 - 2e-31 108.9 10.7 3e-31 108.3 10.7 1.2 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.6 CRK16277.1 - 0.029 14.2 0.1 0.05 13.4 0.1 1.4 1 0 0 1 1 1 0 UBA-like domain PTCB-BRCT PF12738.7 CRK16278.1 - 3.4e-44 148.6 0.1 1.3e-20 73.0 0.0 4.1 4 0 0 4 4 4 3 twin BRCT domain BRCT PF00533.26 CRK16278.1 - 3.4e-35 120.3 0.0 5.2e-12 46.0 0.0 4.5 4 0 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 CRK16278.1 - 1.1e-16 60.9 0.0 5.2e-05 23.6 0.0 4.3 4 0 0 4 4 4 4 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 CRK16278.1 - 8.8e-08 32.3 1.6 0.011 16.0 0.0 3.9 4 0 0 4 4 4 2 DNA ligase 3 BRCT domain Glyoxalase PF00903.25 CRK16278.1 - 2.5e-06 27.7 0.0 7.5e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 CRK16278.1 - 0.0028 17.6 0.0 0.0059 16.5 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase-like domain BRCT_3 PF18428.1 CRK16278.1 - 0.0057 16.7 0.0 14 5.9 0.0 3.4 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 CRK16281.1 - 5.6e-41 138.3 0.3 1.1e-20 73.3 0.0 3.6 4 0 0 4 4 4 3 twin BRCT domain BRCT PF00533.26 CRK16281.1 - 9.9e-31 106.0 0.0 4e-12 46.4 0.0 4.4 4 1 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 CRK16281.1 - 4.7e-15 55.8 0.0 4.3e-05 23.8 0.0 4.3 4 0 0 4 4 4 3 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 CRK16281.1 - 2.8e-08 33.9 0.0 0.0089 16.3 0.0 3.5 3 0 0 3 3 3 2 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 CRK16281.1 - 0.015 15.3 0.0 14 5.9 0.0 3.4 3 0 0 3 3 3 0 BRCA1 C Terminus (BRCT) domain Utp8 PF10395.9 CRK16283.1 - 0.0044 15.6 0.2 0.0081 14.7 0.0 1.5 2 0 0 2 2 2 1 Utp8 family AAA PF00004.29 CRK16284.1 - 1.4e-06 28.8 0.0 7.5e-06 26.4 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 CRK16284.1 - 0.00069 19.6 0.0 0.013 15.4 0.0 2.2 2 0 0 2 2 2 1 Rad17 P-loop domain TIP49 PF06068.13 CRK16284.1 - 0.013 14.8 0.0 0.02 14.1 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_16 PF13191.6 CRK16284.1 - 0.033 14.6 0.0 0.082 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 CRK16284.1 - 0.06 13.6 0.0 0.2 11.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CRK16284.1 - 0.098 13.2 0.0 0.19 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 CRK16284.1 - 0.13 12.3 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 CRK16284.1 - 0.15 11.1 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Ribosomal_60s PF00428.19 CRK16284.1 - 0.19 12.3 4.0 1.2 9.8 0.5 3.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein Cyclin PF08613.11 CRK16285.1 - 7.2e-11 42.7 0.4 1.5e-10 41.7 0.0 1.7 2 0 0 2 2 2 1 Cyclin Anp1 PF03452.14 CRK16291.1 - 2.6e-43 148.4 0.0 3e-43 148.1 0.0 1.0 1 0 0 1 1 1 1 Anp1 DUF3209 PF11483.8 CRK16291.1 - 0.097 13.1 0.0 0.16 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3209) DUF996 PF06195.13 CRK16291.1 - 0.1 12.9 0.4 0.16 12.3 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF996) Xpo1 PF08389.12 CRK16321.1 - 4.9e-08 33.2 0.0 8.8e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Exportin 1-like protein IBN_N PF03810.19 CRK16321.1 - 3.4e-06 26.9 0.0 5.3e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain Glyco_hydro_67M PF07488.12 CRK16325.1 - 4.7e-38 131.1 0.2 6.8e-26 91.1 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67C PF07477.12 CRK16325.1 - 2.2e-13 50.3 0.1 2.9e-13 49.9 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 C-terminus DUF4838 PF16126.5 CRK16325.1 - 0.13 11.6 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4838) Coatomer_WDAD PF04053.14 CRK16327.1 - 1.3e-22 80.4 0.0 1.9e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 CRK16327.1 - 2.7e-09 37.5 1.6 3.2e-05 24.6 0.3 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK16327.1 - 0.0061 16.8 0.1 0.019 15.3 0.1 1.9 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CRK16327.1 - 0.069 11.8 0.1 0.1 11.2 0.1 1.3 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Sulfolobus_pRN PF05584.11 CRK16329.1 - 0.053 13.6 0.0 0.091 12.8 0.0 1.5 1 1 0 1 1 1 0 Sulfolobus plasmid regulatory protein CDC24 PF06395.11 CRK16330.1 - 1.9e-30 104.9 0.1 4.8e-30 103.7 0.1 1.7 1 0 0 1 1 1 1 CDC24 Calponin PH_10 PF15411.6 CRK16330.1 - 2.6e-24 85.8 3.2 1.9e-22 79.8 3.2 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 CRK16330.1 - 6.2e-22 78.7 0.1 1.1e-21 77.9 0.1 1.3 1 0 0 1 1 1 1 RhoGEF domain PB1 PF00564.24 CRK16330.1 - 1e-08 35.0 0.0 2.4e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 PB1 domain WD40 PF00400.32 CRK16331.1 - 4.9e-27 93.6 6.8 0.0003 21.5 0.0 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat F-box-like PF12937.7 CRK16331.1 - 1.4e-13 50.5 1.7 8.6e-13 48.0 0.4 2.5 2 0 0 2 2 2 1 F-box-like ANAPC4_WD40 PF12894.7 CRK16331.1 - 4e-08 33.4 0.1 0.14 12.5 0.0 3.7 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 CRK16331.1 - 1.4e-06 28.1 0.1 3.5e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 CRK16331.1 - 0.17 11.8 0.4 0.72 9.7 0.1 2.2 2 0 0 2 2 2 0 F-box LIN37 PF15306.6 CRK16331.1 - 1.4 9.2 0.0 1.4 9.2 0.0 3.0 3 0 0 3 3 3 0 LIN37 Snf7 PF03357.21 CRK16332.1 - 2.9e-43 147.5 13.7 3.5e-43 147.2 13.7 1.1 1 0 0 1 1 1 1 Snf7 YscO-like PF16789.5 CRK16332.1 - 0.00094 19.3 6.0 0.0017 18.4 6.0 1.4 1 0 0 1 1 1 1 YscO-like protein MscS_porin PF12795.7 CRK16332.1 - 0.0053 16.3 10.5 0.65 9.5 5.0 2.3 1 1 1 2 2 2 2 Mechanosensitive ion channel porin domain CLZ PF16526.5 CRK16332.1 - 0.0075 16.6 7.9 0.22 11.9 0.0 3.4 2 1 1 3 3 3 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels NPV_P10 PF05531.12 CRK16332.1 - 0.012 16.1 9.3 0.6 10.6 0.1 3.1 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Atg14 PF10186.9 CRK16332.1 - 0.013 14.6 6.0 0.017 14.2 6.0 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Alpha-2-MRAP_C PF06401.11 CRK16332.1 - 0.018 15.0 4.6 0.056 13.4 4.1 1.8 1 1 1 2 2 2 0 Alpha-2-macroglobulin RAP, C-terminal domain FlaC_arch PF05377.11 CRK16332.1 - 0.041 14.3 6.8 2 8.9 0.0 3.6 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) FapA PF03961.13 CRK16332.1 - 0.046 12.3 7.0 0.11 11.1 5.1 1.8 1 1 1 2 2 2 0 Flagellar Assembly Protein A DUF2205 PF10224.9 CRK16332.1 - 0.07 13.1 6.1 0.9 9.6 2.7 3.1 2 1 1 3 3 3 0 Short coiled-coil protein Prefoldin PF02996.17 CRK16332.1 - 0.21 11.5 9.1 1.9 8.5 0.1 3.5 3 1 0 3 3 3 0 Prefoldin subunit TMF_DNA_bd PF12329.8 CRK16332.1 - 0.4 10.7 10.4 3 7.9 0.3 3.1 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Endotoxin_N PF03945.14 CRK16332.1 - 0.41 10.3 4.5 1.5 8.5 0.1 2.2 1 1 1 2 2 2 0 delta endotoxin, N-terminal domain ADIP PF11559.8 CRK16332.1 - 0.42 10.7 10.1 7.6 6.6 0.7 2.5 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF848 PF05852.11 CRK16332.1 - 0.52 10.4 6.5 0.46 10.6 4.4 2.0 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF4407 PF14362.6 CRK16332.1 - 0.67 9.2 8.5 0.94 8.8 8.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 CRK16332.1 - 0.92 8.3 12.5 1.5 7.6 11.5 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein bZIP_1 PF00170.21 CRK16332.1 - 0.97 9.6 6.8 2.7 8.2 0.1 3.3 2 1 1 3 3 3 0 bZIP transcription factor Mod_r PF07200.13 CRK16332.1 - 1.1 9.4 11.6 0.81 9.8 8.3 2.0 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DASH_Dam1 PF08653.10 CRK16332.1 - 2 8.3 6.4 13 5.7 0.1 3.4 3 1 0 3 3 3 0 DASH complex subunit Dam1 Muted PF14942.6 CRK16332.1 - 2.3 8.6 9.8 4.8 7.5 6.7 2.2 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein FUSC PF04632.12 CRK16332.1 - 3.3 6.1 4.8 3.3 6.1 1.7 1.8 1 1 1 2 2 2 0 Fusaric acid resistance protein family DUF4446 PF14584.6 CRK16332.1 - 4.4 7.3 8.5 7.4 6.6 2.5 2.5 1 1 3 4 4 4 0 Protein of unknown function (DUF4446) TMPIT PF07851.13 CRK16332.1 - 7.1 5.8 8.7 6.6 5.9 7.0 1.6 1 1 1 2 2 2 0 TMPIT-like protein CCDC-167 PF15188.6 CRK16332.1 - 9.6 6.6 9.7 12 6.3 3.1 3.2 1 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 Beta-lactamase PF00144.24 CRK16335.1 - 5.6e-16 58.7 0.0 7.1e-16 58.4 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.20 CRK16335.1 - 0.071 12.5 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase Beta-lactamase PF00144.24 CRK16336.1 - 1.6e-29 103.2 0.8 2.8e-29 102.4 0.8 1.4 1 1 0 1 1 1 1 Beta-lactamase Glycos_transf_1 PF00534.20 CRK16339.1 - 5e-21 75.0 0.0 1.1e-20 73.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CRK16339.1 - 6.7e-13 49.2 0.0 1.3e-12 48.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 CRK16339.1 - 0.013 15.8 0.0 0.09 13.2 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferases group 1 adh_short PF00106.25 CRK16340.1 - 1.2e-13 50.9 0.0 4.1e-12 46.0 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK16340.1 - 5.2e-05 22.9 0.0 0.00014 21.5 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK16340.1 - 0.021 14.7 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 KR domain HR1 PF02185.16 CRK16340.1 - 0.1 12.8 0.1 5.9 7.1 0.0 3.0 3 1 0 3 3 3 0 Hr1 repeat EGF_2 PF07974.13 CRK16342.1 - 0.26 11.7 2.2 0.45 10.9 2.2 1.4 1 0 0 1 1 1 0 EGF-like domain DNA_pol_A_exo1 PF01612.20 CRK16343.1 - 0.13 12.0 0.1 0.31 10.8 0.0 1.7 2 0 0 2 2 2 0 3'-5' exonuclease Presenilin PF01080.17 CRK16344.1 - 0.093 11.5 1.1 0.1 11.4 1.1 1.2 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.13 CRK16344.1 - 0.76 8.5 7.3 0.88 8.3 7.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4820 PF16091.5 CRK16344.1 - 0.93 8.8 5.8 1.5 8.1 5.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) CDC45 PF02724.14 CRK16344.1 - 0.96 7.7 9.3 1 7.6 9.3 1.1 1 0 0 1 1 1 0 CDC45-like protein ADH_zinc_N PF00107.26 CRK16345.1 - 8.3e-11 42.0 0.0 1.9e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CRK16345.1 - 0.00011 22.1 0.4 0.00096 19.0 0.2 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 CRK16345.1 - 0.032 15.3 0.0 0.061 14.4 0.0 1.6 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Acetyltransf_8 PF13523.6 CRK16346.1 - 3.5e-39 133.8 0.1 5.3e-39 133.2 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Glyco_hydro_11 PF00457.17 CRK16347.1 - 1.5e-75 252.8 17.7 2.7e-75 251.9 17.7 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 MCU PF04678.13 CRK16347.1 - 7.4e-23 81.5 1.0 7.4e-23 81.5 1.0 1.7 2 0 0 2 2 2 1 Mitochondrial calcium uniporter DUF1281 PF06924.11 CRK16347.1 - 0.097 12.2 0.3 0.18 11.3 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1281) DUF3292 PF11696.8 CRK16348.1 - 5.2e-260 864.4 0.0 6.7e-260 864.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) Pex24p PF06398.11 CRK16348.1 - 0.044 12.8 0.0 0.066 12.2 0.0 1.3 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Glyco_hydro_32N PF00251.20 CRK16349.1 - 2e-33 116.3 6.0 1.5e-22 80.6 3.0 2.4 2 1 0 2 2 2 2 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 CRK16349.1 - 3.2e-30 105.2 0.1 4.8e-30 104.6 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal DUF4975 PF16346.5 CRK16349.1 - 0.014 15.5 0.0 0.033 14.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4975) AA_permease_2 PF13520.6 CRK16351.1 - 4.8e-53 180.5 40.4 5.5e-53 180.3 40.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CRK16351.1 - 8.5e-23 80.7 36.7 2.1e-22 79.4 36.7 1.5 1 1 0 1 1 1 1 Amino acid permease Cyto_heme_lyase PF01265.17 CRK16352.1 - 2e-43 149.0 14.6 7.9e-42 143.8 3.2 3.1 1 1 1 2 2 2 2 Cytochrome c/c1 heme lyase DUF3748 PF12566.8 CRK16352.1 - 0.0035 17.3 0.0 0.0059 16.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3748) SPX PF03105.19 CRK16352.1 - 5 6.9 6.2 6.4 6.6 6.2 1.1 1 0 0 1 1 1 0 SPX domain PHO4 PF01384.20 CRK16354.1 - 2.5e-109 365.4 12.8 3.1e-109 365.1 12.8 1.1 1 0 0 1 1 1 1 Phosphate transporter family CLN3 PF02487.17 CRK16355.1 - 3.1e-150 500.7 0.3 4.2e-150 500.2 0.3 1.1 1 0 0 1 1 1 1 CLN3 protein MFS_1 PF07690.16 CRK16355.1 - 1.3e-07 30.9 15.0 3.4e-05 22.9 0.1 3.8 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF4637 PF15470.6 CRK16355.1 - 0.18 11.5 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) ATG_C PF09333.11 CRK16356.1 - 0.094 13.1 0.1 0.26 11.7 0.1 1.7 1 0 0 1 1 1 0 Autophagy-related protein C terminal domain DUF1454 PF07305.12 CRK16356.1 - 0.1 12.0 0.0 0.24 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1454) PHM7_cyt PF14703.6 CRK16359.1 - 3.9e-14 53.3 0.0 4.9e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 CRK16359.1 - 2.4e-11 43.6 0.0 3.8e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport kleA_kleC PF17383.2 CRK16359.1 - 0.024 15.0 0.1 0.038 14.3 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized KorC regulated protein A LDB19 PF13002.7 CRK16365.1 - 4.5e-15 55.9 0.4 1.5e-14 54.2 0.1 1.8 2 0 0 2 2 2 1 Arrestin_N terminal like CSN8_PSD8_EIF3K PF10075.9 CRK16382.1 - 5.4e-19 68.6 0.0 7.6e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 CRK16382.1 - 0.072 12.5 0.0 0.093 12.1 0.0 1.2 1 0 0 1 1 1 0 SAC3/GANP family UCH PF00443.29 CRK16396.1 - 0.00048 19.7 0.2 0.00063 19.3 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Sel1 PF08238.12 CRK16401.1 - 0.018 15.7 4.9 5.6 7.8 0.7 3.6 3 1 0 3 3 3 0 Sel1 repeat PX PF00787.24 CRK16402.1 - 1e-23 83.5 0.0 1.5e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 PX domain NAD_binding_8 PF13450.6 CRK16403.1 - 1.3e-09 38.1 0.1 4.2e-09 36.5 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 CRK16403.1 - 1.2e-08 34.7 0.0 1.3e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 CRK16403.1 - 0.08 12.5 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase RNR_inhib PF08591.10 CRK16405.1 - 9.4e-34 116.9 0.0 3.4e-33 115.2 0.0 1.9 2 1 0 2 2 2 1 Ribonucleotide reductase inhibitor Pkinase_C PF00433.24 CRK16405.1 - 0.035 14.8 0.7 0.36 11.6 0.1 2.7 2 1 0 2 2 2 0 Protein kinase C terminal domain SIP1 PF04938.12 CRK16406.1 - 7.8e-09 35.6 0.0 0.00086 19.1 0.0 3.3 3 0 0 3 3 3 3 Survival motor neuron (SMN) interacting protein 1 (SIP1) Ribosomal_S14 PF00253.21 CRK16407.1 - 3.5e-11 42.7 2.7 5.3e-11 42.1 0.7 2.0 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e QLQ PF08880.11 CRK16407.1 - 0.01 15.5 1.3 0.013 15.3 0.0 1.8 2 0 0 2 2 2 0 QLQ T2SSppdC PF12528.8 CRK16407.1 - 0.033 14.9 1.0 0.046 14.5 1.0 1.1 1 0 0 1 1 1 0 Type II secretion prepilin peptidase dependent protein C SpoIIIAH PF12685.7 CRK16407.1 - 0.075 12.9 0.1 0.089 12.6 0.1 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein PTR2 PF00854.21 CRK16409.1 - 2.6e-43 148.4 3.4 3.4e-43 148.0 3.4 1.2 1 0 0 1 1 1 1 POT family ARPC4 PF05856.12 CRK16409.1 - 0.15 11.6 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 ARP2/3 complex 20 kDa subunit (ARPC4) Gpr1_Fun34_YaaH PF01184.19 CRK16411.1 - 1.1e-42 146.0 17.5 1.3e-42 145.8 17.5 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Acyl-CoA_dh_2 PF08028.11 CRK16412.1 - 7e-14 52.2 0.3 1.3e-13 51.4 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 CRK16412.1 - 1.1e-05 25.5 0.1 8.7e-05 22.6 0.0 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 CRK16412.1 - 1.2e-05 25.9 0.0 2.2e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 CRK16412.1 - 0.032 14.4 0.1 0.071 13.3 0.1 1.7 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain Pectate_lyase PF03211.13 CRK16413.1 - 3.4e-84 281.5 6.9 3.9e-84 281.3 6.9 1.0 1 0 0 1 1 1 1 Pectate lyase MIP PF00230.20 CRK16414.1 - 3e-34 118.7 0.8 4e-34 118.3 0.8 1.1 1 0 0 1 1 1 1 Major intrinsic protein Sugar_tr PF00083.24 CRK16415.1 - 7.1e-119 397.6 22.5 8.2e-119 397.4 22.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK16415.1 - 3.3e-25 88.8 60.3 8e-23 80.9 31.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 CRK16415.1 - 0.0019 16.8 0.1 0.0019 16.8 0.1 4.0 3 1 1 4 4 4 1 MFS/sugar transport protein DUF1772 PF08592.11 CRK16415.1 - 2.2 8.6 14.9 6 7.2 1.0 3.8 2 1 0 3 3 3 0 Domain of unknown function (DUF1772) DUF3602 PF12223.8 CRK16416.1 - 0.021 15.4 2.2 0.042 14.4 2.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3602) Glyco_hydro_7 PF00840.20 CRK16418.1 - 6.5e-132 440.3 0.2 8.9e-132 439.9 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 DHR10 PF18595.1 CRK16418.1 - 0.018 15.1 1.5 0.033 14.2 1.5 1.4 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain p450 PF00067.22 CRK16419.1 - 2.2e-14 53.1 0.0 5.5e-14 51.8 0.0 1.5 2 0 0 2 2 2 1 Cytochrome P450 HET PF06985.11 CRK16420.1 - 4.7e-05 23.8 1.2 0.0048 17.3 1.2 2.4 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Zn_clus PF00172.18 CRK16421.1 - 1e-15 57.5 26.9 2.5e-08 33.9 11.1 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 CRK16421.1 - 7.6e-05 21.9 0.2 0.00023 20.3 0.1 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.8 CRK16421.1 - 2.5 6.8 5.1 0.24 10.2 0.1 1.7 2 0 0 2 2 2 0 Fungal specific transcription factor domain DIOX_N PF14226.6 CRK16422.1 - 2.1e-29 102.7 0.0 2.2e-27 96.1 0.0 2.3 2 0 0 2 2 2 2 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 CRK16422.1 - 1.1e-15 58.0 0.0 1.9e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 CRK16423.1 - 1e-32 113.5 31.4 1e-32 113.5 31.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK16423.1 - 1.6e-13 50.4 7.2 1.6e-13 50.4 7.2 2.1 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 CRK16423.1 - 4.5e-06 25.4 2.3 4.5e-06 25.4 2.3 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) BT1 PF03092.16 CRK16423.1 - 0.0024 16.2 0.2 0.0051 15.1 0.2 1.5 1 0 0 1 1 1 1 BT1 family Vut_1 PF02592.15 CRK16423.1 - 2.6 8.4 13.4 3.8 7.8 2.1 2.9 2 1 0 2 2 2 0 Putative vitamin uptake transporter NACHT PF05729.12 CRK16424.1 - 0.00018 21.5 0.3 0.45 10.4 0.0 2.3 2 0 0 2 2 2 2 NACHT domain AAA_16 PF13191.6 CRK16424.1 - 0.0015 18.9 0.1 0.026 14.9 0.0 3.0 2 2 1 3 3 3 1 AAA ATPase domain MIOX PF05153.15 CRK16424.1 - 0.0017 18.0 0.0 1.8 8.1 0.0 2.9 2 1 1 3 3 3 2 Myo-inositol oxygenase AAA_22 PF13401.6 CRK16424.1 - 0.0019 18.5 0.0 0.0085 16.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 CRK16424.1 - 0.0041 16.4 0.0 0.0077 15.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.22 CRK16424.1 - 0.021 14.0 0.0 0.089 12.0 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain APS_kinase PF01583.20 CRK16424.1 - 0.066 13.1 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 Adenylylsulphate kinase CK2S PF15011.6 CRK16424.1 - 0.09 12.7 0.0 4.3 7.2 0.0 2.5 2 0 0 2 2 2 0 Casein Kinase 2 substrate AAA_33 PF13671.6 CRK16424.1 - 0.13 12.4 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 CRK16424.1 - 0.17 11.9 0.0 0.37 10.8 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 CRK16424.1 - 0.17 11.1 0.0 0.44 9.8 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin SurE PF01975.17 CRK16425.1 - 1.4e-24 87.0 0.1 2e-24 86.4 0.1 1.2 1 0 0 1 1 1 1 Survival protein SurE Acetyltransf_1 PF00583.25 CRK16426.1 - 1.7e-05 25.0 0.0 3.4e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CRK16426.1 - 0.002 18.5 0.0 0.0033 17.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CRK16426.1 - 0.077 12.9 0.0 0.23 11.4 0.0 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3176 PF11374.8 CRK16429.1 - 1e-28 99.7 0.3 1.9e-28 98.8 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) PI-PLC-X PF00388.19 CRK16431.1 - 4e-47 159.4 0.0 6e-47 158.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 CRK16431.1 - 4e-39 133.5 0.0 6.5e-39 132.8 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain IMUP PF15761.5 CRK16431.1 - 0.0065 17.2 2.7 0.016 15.9 2.7 1.6 1 0 0 1 1 1 1 Immortalisation up-regulated protein DUF4701 PF15773.5 CRK16431.1 - 0.046 12.7 2.9 0.079 11.9 2.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4701) C2 PF00168.30 CRK16431.1 - 0.051 13.9 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 C2 domain YL1 PF05764.13 CRK16431.1 - 0.087 12.9 1.4 0.5 10.5 1.8 1.9 2 0 0 2 2 2 0 YL1 nuclear protein NB-ARC PF00931.22 CRK16433.1 - 8.2e-09 35.0 0.0 1.4e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 CRK16433.1 - 2.9e-07 31.0 0.0 6.6e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain PGAP1 PF07819.13 CRK16433.1 - 0.018 14.7 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Syntaxin-6_N PF09177.11 CRK16433.1 - 0.075 13.6 0.0 0.27 11.8 0.0 1.9 1 0 0 1 1 1 0 Syntaxin 6, N-terminal DUF676 PF05057.14 CRK16433.1 - 0.082 12.4 0.1 0.23 10.9 0.1 1.7 1 1 0 1 1 1 0 Putative serine esterase (DUF676) ATPase_2 PF01637.18 CRK16433.1 - 0.094 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Transferase PF02458.15 CRK16434.1 - 8.9e-07 27.9 0.0 1.3e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Transferase family Transferase PF02458.15 CRK16435.1 - 1.4e-05 24.0 0.0 0.0034 16.1 0.0 2.0 2 0 0 2 2 2 2 Transferase family Glyco_hydro_7 PF00840.20 CRK16436.1 - 2.4e-39 135.3 0.0 3e-39 135.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Nucleotid_trans PF03407.16 CRK16437.1 - 0.00095 19.2 0.0 0.0015 18.6 0.0 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Glyco_transf_34 PF05637.12 CRK16437.1 - 0.037 13.8 0.2 0.057 13.1 0.2 1.2 1 0 0 1 1 1 0 galactosyl transferase GMA12/MNN10 family Antimicrobial_5 PF08026.11 CRK16437.1 - 0.52 10.4 2.2 1.9 8.6 2.2 2.0 1 0 0 1 1 1 0 Bee antimicrobial peptide DUF1689 PF07954.11 CRK16439.1 - 0.019 15.4 0.0 0.024 15.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1689) Romo1 PF10247.9 CRK16439.1 - 0.031 14.6 1.2 5 7.6 0.2 2.3 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 Ni_hydr_CYTB PF01292.20 CRK16439.1 - 0.08 12.5 0.0 0.095 12.3 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 Abhydrolase_1 PF00561.20 CRK16440.1 - 2e-14 53.9 0.0 3.3e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CRK16440.1 - 4e-09 37.4 4.6 5.7e-07 30.4 0.0 2.1 2 0 0 2 2 2 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CRK16440.1 - 0.0002 20.7 0.0 0.00034 19.9 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 CRK16440.1 - 0.068 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Ndr PF03096.14 CRK16440.1 - 0.11 11.2 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 Ndr family UPF0227 PF05728.12 CRK16440.1 - 0.14 12.1 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) PetL PF05115.14 CRK16441.1 - 0.09 12.8 3.7 0.35 10.9 3.7 2.0 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit VI (PetL) Pkinase PF00069.25 CRK16442.1 - 3.3e-05 23.4 0.0 0.00049 19.6 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Choline_kinase PF01633.20 CRK16442.1 - 0.0022 17.6 0.0 0.004 16.8 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 CRK16442.1 - 0.0035 17.3 1.5 0.0094 15.9 1.5 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family FAD_syn PF06574.12 CRK16442.1 - 0.097 12.6 0.1 0.13 12.1 0.1 1.2 1 0 0 1 1 1 0 FAD synthetase PWI PF01480.17 CRK16450.1 - 5e-15 55.6 1.8 5.1e-15 55.5 0.3 1.8 3 0 0 3 3 3 1 PWI domain Iso_dh PF00180.20 CRK16468.1 - 6.7e-32 111.0 0.0 7.6e-32 110.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase NTP_transf_6 PF06042.11 CRK16468.1 - 0.19 11.6 0.1 0.81 9.5 0.1 1.8 2 0 0 2 2 2 0 Nucleotidyltransferase MBF1 PF08523.10 CRK16486.1 - 5.8e-08 33.1 0.2 6.2e-08 33.0 0.2 1.0 1 0 0 1 1 1 1 Multiprotein bridging factor 1 ATP-synt_ab PF00006.25 CRK16490.1 - 3e-14 53.2 0.1 5.3e-14 52.4 0.1 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain T3SS_ATPase_C PF18269.1 CRK16490.1 - 0.0043 16.9 0.9 0.042 13.7 0.9 2.2 1 1 0 1 1 1 1 T3SS EscN ATPase C-terminal domain DNA_pol_delta_4 PF04081.13 CRK16492.1 - 9.5e-16 58.3 0.1 2.4e-15 57.0 0.1 1.7 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 Q_salvage PF10343.9 CRK16493.1 - 7.5e-128 426.0 0.0 9.5e-128 425.7 0.0 1.1 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family DUF1563 PF07599.11 CRK16493.1 - 0.062 13.4 0.1 0.12 12.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1563) ThiF PF00899.21 CRK16494.1 - 2.1e-41 141.9 0.0 3e-41 141.4 0.0 1.1 1 0 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 CRK16494.1 - 2e-22 79.6 0.4 3.8e-22 78.7 0.4 1.5 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 CRK16494.1 - 1.8e-07 31.3 0.4 3.3e-05 23.9 0.0 2.5 1 1 0 2 2 2 2 Ubiquitin-activating enzyme active site E2_bind PF08825.10 CRK16494.1 - 0.082 13.1 0.4 0.22 11.7 0.1 1.9 2 0 0 2 2 2 0 E2 binding domain DASH_Dam1 PF08653.10 CRK16494.1 - 0.19 11.5 0.8 3.4 7.5 0.2 2.4 2 0 0 2 2 2 0 DASH complex subunit Dam1 adh_short_C2 PF13561.6 CRK16495.1 - 8e-47 159.8 2.1 2.2e-40 138.7 0.2 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRK16495.1 - 5.6e-42 143.4 1.9 2.6e-32 111.8 0.1 2.1 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.10 CRK16495.1 - 6.5e-07 29.4 1.7 1.3e-06 28.4 1.7 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 CRK16495.1 - 1.6e-05 24.5 0.1 7.7e-05 22.3 0.1 2.1 3 1 0 3 3 3 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 CRK16495.1 - 0.0013 18.6 0.0 0.0028 17.5 0.0 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DFP PF04127.15 CRK16495.1 - 0.0039 17.0 1.6 0.25 11.1 0.1 2.7 2 1 0 2 2 2 1 DNA / pantothenate metabolism flavoprotein F420_oxidored PF03807.17 CRK16495.1 - 0.024 15.2 0.0 0.055 14.0 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent RmlD_sub_bind PF04321.17 CRK16495.1 - 0.034 13.2 0.3 0.14 11.2 0.3 2.0 1 1 0 1 1 1 0 RmlD substrate binding domain ApbA PF02558.16 CRK16495.1 - 0.038 13.6 0.0 0.069 12.8 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA THF_DHG_CYH_C PF02882.19 CRK16495.1 - 0.039 13.3 0.0 0.38 10.1 0.0 2.1 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1776 PF08643.10 CRK16495.1 - 0.072 12.5 0.0 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.15 CRK16495.1 - 0.076 12.1 0.0 0.15 11.2 0.0 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Esterase_phd PF10503.9 CRK16496.1 - 9.6e-26 90.6 1.3 1.3e-25 90.2 1.3 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 CRK16496.1 - 5.3e-10 39.1 0.2 9e-10 38.4 0.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 CRK16496.1 - 0.014 15.3 0.1 0.041 13.7 0.1 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold AXE1 PF05448.12 CRK16496.1 - 0.074 11.7 0.1 0.11 11.1 0.1 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) PAP2 PF01569.21 CRK16497.1 - 1.8e-18 66.6 1.1 1.8e-18 66.6 1.1 2.1 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 CRK16497.1 - 0.0004 20.1 3.1 0.0004 20.1 3.1 2.1 2 0 0 2 2 2 1 PAP2 superfamily JmjC PF02373.22 CRK16498.1 - 4.3e-37 127.0 0.5 4.3e-37 127.0 0.5 2.2 2 0 0 2 2 2 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.6 CRK16498.1 - 2.4e-18 66.3 7.2 5e-18 65.3 7.2 1.6 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 CRK16498.1 - 1e-17 64.2 6.7 1e-17 64.2 6.7 2.5 2 0 0 2 2 2 1 PHD-like zinc-binding domain JmjN PF02375.17 CRK16498.1 - 3.1e-15 55.8 0.6 8.2e-15 54.5 0.6 1.8 1 0 0 1 1 1 1 jmjN domain Cellulase PF00150.18 CRK16498.1 - 1.2e-13 51.2 0.1 1.2e-13 51.2 0.1 3.1 2 1 1 3 3 3 1 Cellulase (glycosyl hydrolase family 5) PHD PF00628.29 CRK16498.1 - 0.33 10.9 2.0 0.91 9.5 2.0 1.8 1 0 0 1 1 1 0 PHD-finger DUF1479 PF07350.12 CRK16499.1 - 8.5e-165 548.5 0.0 1.1e-164 548.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.13 CRK16499.1 - 0.0088 16.3 0.2 3.8 7.7 0.0 2.4 2 0 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) GFO_IDH_MocA PF01408.22 CRK16500.1 - 1.7e-17 64.3 0.0 2.8e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 CRK16500.1 - 0.0006 19.8 0.0 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain adh_short PF00106.25 CRK16501.1 - 0.00063 19.3 0.1 0.00078 19.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CRK16501.1 - 0.03 14.2 0.1 0.045 13.7 0.1 1.2 1 0 0 1 1 1 0 KR domain Amidase PF01425.21 CRK16502.1 - 3.9e-66 223.9 0.0 2.8e-64 217.8 0.0 2.2 1 1 0 1 1 1 1 Amidase HCV_NS5a PF01506.19 CRK16502.1 - 0.18 11.7 0.1 0.18 11.7 0.1 2.0 2 0 0 2 2 2 0 Hepatitis C virus non-structural 5a protein membrane anchor p450 PF00067.22 CRK16504.1 - 2.3e-69 234.3 0.0 3.4e-69 233.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 CRK16504.1 - 1.2e-33 116.5 0.0 2.1e-33 115.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 CRK16504.1 - 1.6e-24 86.8 0.0 4.4e-24 85.3 0.0 1.8 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 CRK16504.1 - 1.5e-12 48.1 0.0 4e-12 46.7 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 CRK16504.1 - 0.036 14.3 0.0 0.11 12.7 0.0 1.8 2 0 0 2 2 2 0 Flavodoxin domain Peptidase_S8 PF00082.22 CRK16505.1 - 5.1e-28 98.2 9.9 5.1e-28 98.2 9.9 1.3 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 CRK16505.1 - 2.2e-18 66.7 0.0 4e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Epimerase PF01370.21 CRK16506.1 - 1.9e-07 30.8 0.3 2.2e-06 27.3 0.3 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 CRK16506.1 - 2e-06 27.8 0.2 4.9e-05 23.3 0.2 2.5 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 CRK16506.1 - 0.00014 21.1 0.0 0.00032 20.0 0.0 1.7 1 0 0 1 1 1 1 Male sterility protein Sacchrp_dh_NADP PF03435.18 CRK16506.1 - 0.0003 21.0 0.0 0.00053 20.3 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 CRK16506.1 - 0.00086 18.9 0.3 0.002 17.7 0.0 1.8 2 0 0 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.19 CRK16506.1 - 0.0035 16.4 0.0 0.074 12.1 0.0 2.2 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.20 CRK16506.1 - 0.0086 16.1 0.0 0.024 14.7 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase KGG PF10685.9 CRK16507.1 - 9.7e-19 67.0 18.2 5.5e-07 29.7 0.6 3.8 3 0 0 3 3 3 3 Stress-induced bacterial acidophilic repeat motif Zn_clus PF00172.18 CRK16507.1 - 0.0002 21.4 10.6 0.0039 17.3 10.6 2.3 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain bZIP_2 PF07716.15 CRK16507.1 - 0.0015 18.5 1.5 0.0015 18.5 1.5 2.2 2 0 0 2 2 2 1 Basic region leucine zipper TMF_TATA_bd PF12325.8 CRK16507.1 - 0.065 13.5 3.5 0.31 11.3 0.1 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF148 PF02520.17 CRK16507.1 - 0.07 13.2 0.5 0.2 11.8 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF148 BRE1 PF08647.11 CRK16507.1 - 2.1 8.5 5.6 11 6.1 0.3 2.4 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DivIC PF04977.15 CRK16507.1 - 4.7 7.1 7.5 13 5.7 0.4 2.3 2 0 0 2 2 2 0 Septum formation initiator DUF4407 PF14362.6 CRK16507.1 - 5 6.4 6.5 4.5 6.5 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) zf-met PF12874.7 CRK16508.1 - 8.7e-13 48.2 23.4 0.0016 18.7 0.8 6.0 6 0 0 6 6 6 4 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 CRK16508.1 - 3e-12 46.3 32.3 0.13 13.2 0.2 7.7 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CRK16508.1 - 3.1e-12 46.4 20.3 2.7e-05 24.3 0.8 5.9 6 0 0 6 6 6 4 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 CRK16508.1 - 1.8e-10 40.6 36.5 0.0079 16.6 0.1 7.0 7 1 0 7 7 7 4 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 CRK16508.1 - 4.6e-10 39.7 25.5 0.01 16.1 0.4 5.5 2 2 3 5 5 5 3 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.6 CRK16508.1 - 0.0028 18.0 27.4 0.18 12.3 0.1 6.8 7 0 0 7 7 7 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 CRK16508.1 - 0.0064 16.5 10.4 1.8 8.6 0.1 4.8 4 0 0 4 4 4 2 C2H2-type zinc finger Zn_ribbon_recom PF13408.6 CRK16508.1 - 0.015 15.8 0.4 0.015 15.8 0.4 3.7 3 1 0 4 4 4 0 Recombinase zinc beta ribbon domain zf-C2H2_9 PF16293.5 CRK16508.1 - 0.17 11.7 16.5 0.29 11.0 0.0 5.6 5 2 2 7 7 7 0 C2H2 type zinc-finger (1 copy) AKAP95 PF04988.12 CRK16508.1 - 0.58 10.4 9.6 1 9.6 0.1 3.4 2 1 1 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_11 PF16622.5 CRK16508.1 - 4.9 7.0 21.2 2.1 8.2 0.2 4.9 5 0 0 5 5 5 0 zinc-finger C2H2-type Rad50_zn_hook PF04423.14 CRK16508.1 - 5.1 7.0 0.0 5.1 7.0 0.0 4.0 5 0 0 5 5 4 0 Rad50 zinc hook motif Ribosomal_L32p PF01783.23 CRK16510.1 - 2e-13 50.3 5.5 2.9e-13 49.9 5.5 1.2 1 0 0 1 1 1 1 Ribosomal L32p protein family zf-ribbon_3 PF13248.6 CRK16510.1 - 0.013 14.9 3.9 0.022 14.2 3.9 1.3 1 0 0 1 1 1 0 zinc-ribbon domain zinc-ribbons_6 PF07191.12 CRK16510.1 - 0.031 14.3 1.4 0.046 13.7 1.4 1.2 1 0 0 1 1 1 0 zinc-ribbons Sgf11 PF08209.11 CRK16510.1 - 0.22 11.1 4.0 1.7 8.3 0.1 2.3 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) PolC_DP2 PF03833.13 CRK16510.1 - 0.29 8.9 0.4 0.33 8.8 0.4 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 PhnA_Zn_Ribbon PF08274.12 CRK16510.1 - 0.91 9.5 0.1 0.91 9.5 0.1 2.1 2 0 0 2 2 2 0 PhnA Zinc-Ribbon Septin PF00735.18 CRK16511.1 - 1.3e-112 375.7 0.4 1.6e-112 375.4 0.4 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 CRK16511.1 - 1.8e-07 31.3 0.0 4.2e-07 30.0 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 CRK16511.1 - 1.9e-05 24.1 0.0 3.3e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.27 CRK16511.1 - 4.3e-05 23.1 0.7 0.017 14.7 0.1 2.4 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CRK16511.1 - 6.3e-05 22.9 0.1 0.0006 19.8 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 CRK16511.1 - 0.0016 18.5 0.1 1.7 8.6 0.1 2.5 2 0 0 2 2 2 2 Dynamin family NB-ARC PF00931.22 CRK16511.1 - 0.0034 16.6 0.1 0.0059 15.8 0.1 1.3 1 0 0 1 1 1 1 NB-ARC domain ABC_tran PF00005.27 CRK16511.1 - 0.0082 16.7 0.5 0.016 15.7 0.5 1.9 1 1 0 1 1 1 1 ABC transporter AAA_7 PF12775.7 CRK16511.1 - 0.0099 15.4 0.0 0.065 12.7 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_22 PF13401.6 CRK16511.1 - 0.01 16.1 0.0 0.023 15.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CRK16511.1 - 0.016 15.6 0.0 0.041 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Gtr1_RagA PF04670.12 CRK16511.1 - 0.038 13.3 0.0 0.52 9.6 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region FtsK_SpoIIIE PF01580.18 CRK16511.1 - 0.079 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family G-alpha PF00503.20 CRK16511.1 - 0.1 11.7 0.5 0.62 9.2 0.2 2.0 1 1 1 2 2 2 0 G-protein alpha subunit Microtub_bd PF16796.5 CRK16511.1 - 0.1 12.5 0.3 0.55 10.2 0.1 2.1 2 0 0 2 2 2 0 Microtubule binding AAA_29 PF13555.6 CRK16511.1 - 0.18 11.5 0.0 0.4 10.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Glyco_hydro_72 PF03198.14 CRK16512.1 - 9.1e-114 379.9 0.1 1.2e-113 379.6 0.1 1.1 1 0 0 1 1 1 1 Glucanosyltransferase MFS_1 PF07690.16 CRK16512.1 - 1.1e-37 129.8 47.3 6.9e-32 110.7 25.7 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CRK16512.1 - 3.4e-08 32.4 9.1 6.3e-08 31.5 9.1 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 CRK16512.1 - 1.1e-05 24.3 8.4 1.1e-05 24.3 8.4 3.0 2 1 1 3 3 3 2 MFS/sugar transport protein Carn_acyltransf PF00755.20 CRK16513.1 - 1.4e-168 562.2 0.2 2.9e-149 498.4 0.0 2.8 1 1 1 2 2 2 2 Choline/Carnitine o-acyltransferase XRCC4 PF06632.12 CRK16513.1 - 0.04 12.8 0.5 0.2 10.5 0.0 2.0 2 0 0 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Adeno_E3_CR2 PF02439.15 CRK16514.1 - 0.051 13.3 0.0 0.097 12.4 0.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EphA2_TM PF14575.6 CRK16514.1 - 0.052 14.4 0.0 0.13 13.2 0.0 1.7 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Yip1 PF04893.17 CRK16514.1 - 0.071 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Yip1 domain Rad51 PF08423.11 CRK16516.1 - 2.3e-41 141.7 0.0 1.4e-40 139.2 0.0 1.9 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.6 CRK16516.1 - 9.7e-08 31.8 0.0 2.2e-07 30.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain RecA PF00154.21 CRK16516.1 - 2.7e-05 23.8 0.1 0.006 16.1 0.0 2.3 2 0 0 2 2 2 2 recA bacterial DNA recombination protein ATPase PF06745.13 CRK16516.1 - 2.9e-05 23.5 0.0 4.7e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 KaiC AAA_24 PF13479.6 CRK16516.1 - 0.007 16.1 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 CRK16516.1 - 0.027 13.8 0.0 0.35 10.2 0.0 2.2 1 1 0 1 1 1 0 DnaB-like helicase C terminal domain CbiA PF01656.23 CRK16516.1 - 0.042 13.9 0.0 1.3 9.1 0.0 2.6 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain NACHT PF05729.12 CRK16516.1 - 0.057 13.3 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.6 CRK16516.1 - 0.085 13.1 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Ras PF00071.22 CRK16518.1 - 2e-65 219.3 0.5 2.4e-65 219.1 0.5 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CRK16518.1 - 6.9e-36 123.1 0.1 1.3e-35 122.3 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CRK16518.1 - 3.3e-16 59.2 0.1 3.9e-16 59.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CRK16518.1 - 1.5e-05 25.0 0.3 0.13 12.2 0.0 2.3 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 CRK16518.1 - 1.8e-05 24.8 0.1 9.3e-05 22.5 0.0 2.0 1 1 1 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CRK16518.1 - 3.5e-05 23.4 0.4 9.3e-05 22.0 0.2 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CRK16518.1 - 0.00024 20.5 0.1 0.00031 20.2 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 CRK16518.1 - 0.00054 19.4 0.0 0.00084 18.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 CRK16518.1 - 0.00096 18.7 0.0 0.0056 16.2 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA PF00004.29 CRK16518.1 - 0.0012 19.3 0.1 0.15 12.5 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CRK16518.1 - 0.009 16.4 0.0 0.012 16.0 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CRK16518.1 - 0.033 14.5 0.0 0.068 13.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CRK16518.1 - 0.057 13.2 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.18 CRK16518.1 - 0.067 12.5 0.0 0.18 11.0 0.0 1.7 2 0 0 2 2 2 0 Septin TniB PF05621.11 CRK16518.1 - 0.07 12.5 0.0 0.21 11.0 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein AAA_5 PF07728.14 CRK16518.1 - 0.077 13.0 0.0 0.13 12.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 CRK16518.1 - 0.082 12.4 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 CRK16518.1 - 0.09 13.3 0.1 0.16 12.5 0.1 1.7 1 1 0 1 1 1 0 ABC transporter PduV-EutP PF10662.9 CRK16518.1 - 0.099 12.4 0.1 1.2 8.8 0.0 2.2 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.6 CRK16518.1 - 0.12 12.0 0.1 1.6 8.3 0.0 2.2 2 1 0 2 2 2 0 AAA domain Fungal_trans PF04082.18 CRK16520.1 - 1.8e-21 76.3 0.5 1.8e-21 76.3 0.5 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain p450 PF00067.22 CRK16523.1 - 5.1e-53 180.4 0.0 7.3e-53 179.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3626 PF12294.8 CRK16524.1 - 0.013 14.6 0.1 0.016 14.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3626) YccF PF03733.13 CRK16525.1 - 5.1e-16 59.1 12.5 5.1e-16 59.1 12.5 3.9 4 0 0 4 4 4 2 Inner membrane component domain Na_Ca_ex PF01699.24 CRK16525.1 - 3.5e-09 36.8 12.5 7.6e-08 32.5 2.1 3.8 5 0 0 5 5 5 2 Sodium/calcium exchanger protein eIF-3c_N PF05470.12 CRK16525.1 - 0.92 7.7 5.1 1.3 7.2 5.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DEAD PF00270.29 CRK16527.1 - 6.4e-35 120.5 0.0 7.6e-35 120.3 0.0 1.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase CMS1 PF14617.6 CRK16527.1 - 0.0043 16.4 0.0 0.0066 15.8 0.0 1.2 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.15 CRK16527.1 - 0.012 15.6 0.0 0.016 15.2 0.0 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit RRM_1 PF00076.22 CRK16529.1 - 7.1e-17 61.0 0.0 1e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CRK16529.1 - 0.029 14.4 0.0 0.048 13.7 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 CRK16529.1 - 0.081 12.8 0.0 0.16 11.9 0.0 1.5 1 1 0 1 1 1 0 Occluded RNA-recognition motif BLOC1_2 PF10046.9 CRK16529.1 - 0.093 13.0 0.2 0.13 12.6 0.2 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TRP PF06011.12 CRK16544.1 - 4.9e-80 269.3 16.8 5.8e-80 269.1 16.8 1.0 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TPR_21 PF09976.9 CRK16544.1 - 0.18 11.5 0.7 0.31 10.7 0.7 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain DUF4131 PF13567.6 CRK16544.1 - 0.23 11.1 4.7 0.44 10.2 0.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) SirB PF04247.12 CRK16544.1 - 1.3 9.1 11.4 0.16 12.1 6.8 1.9 2 0 0 2 2 2 0 Invasion gene expression up-regulator, SirB DUF3180 PF11377.8 CRK16544.1 - 8.9 6.5 11.6 0.21 11.7 0.9 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF3180) Cpn60_TCP1 PF00118.24 CRK16566.1 - 1.2e-57 195.7 0.0 1.3e-57 195.6 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family AMP-binding PF00501.28 CRK16570.1 - 1.3e-35 122.8 0.0 1.6e-35 122.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Con-6 PF10346.9 CRK16571.1 - 0.022 14.8 0.4 0.037 14.1 0.4 1.4 1 0 0 1 1 1 0 Conidiation protein 6 Fringe PF02434.16 CRK16572.1 - 3e-06 26.8 1.0 3.7e-05 23.3 1.0 2.2 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 CRK16572.1 - 0.012 15.5 0.0 0.027 14.3 0.0 1.6 1 1 0 1 1 1 0 Galactosyltransferase PAN_4 PF14295.6 CRK16572.1 - 0.057 13.3 0.3 0.057 13.3 0.3 2.1 2 0 0 2 2 2 0 PAN domain AAA PF00004.29 CRK16573.1 - 6.4e-16 59.0 0.0 1e-15 58.4 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 CRK16573.1 - 2.6e-14 53.4 0.0 6.3e-14 52.1 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 CRK16573.1 - 3.1e-11 43.3 0.0 1.3e-07 31.6 0.0 2.5 3 0 0 3 3 3 2 DNA polymerase III, delta subunit Rad17 PF03215.15 CRK16573.1 - 4.1e-08 33.4 0.0 8.4e-08 32.4 0.0 1.6 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 CRK16573.1 - 7.2e-07 29.5 0.0 2.3e-06 27.9 0.0 1.9 2 0 0 2 2 1 1 AAA C-terminal domain AAA_30 PF13604.6 CRK16573.1 - 1.7e-06 27.9 0.1 5.9e-06 26.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 CRK16573.1 - 2.8e-06 27.2 0.0 4.5e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CRK16573.1 - 7.8e-06 25.9 0.1 3.4e-05 23.8 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CRK16573.1 - 1.5e-05 25.4 0.0 0.00011 22.6 0.0 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CRK16573.1 - 1.5e-05 25.3 0.0 4.7e-05 23.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CRK16573.1 - 1.9e-05 24.6 0.1 0.00019 21.3 0.0 2.2 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 CRK16573.1 - 0.00027 20.2 0.0 0.00042 19.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 CRK16573.1 - 0.00036 20.3 0.0 0.00057 19.6 0.0 1.2 1 0 0 1 1 1 1 Sigma-54 interaction domain RuvB_N PF05496.12 CRK16573.1 - 0.00061 19.6 0.0 0.0014 18.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DNA_pol3_delta PF06144.13 CRK16573.1 - 0.00061 19.6 0.0 0.001 18.9 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_14 PF13173.6 CRK16573.1 - 0.00076 19.5 0.0 0.0017 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CRK16573.1 - 0.0012 19.2 0.0 0.0033 17.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.11 CRK16573.1 - 0.002 18.0 0.0 0.017 15.0 0.0 2.4 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 CRK16573.1 - 0.0031 17.8 0.0 0.0058 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 CRK16573.1 - 0.004 16.5 0.0 0.013 14.9 0.0 1.8 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI TniB PF05621.11 CRK16573.1 - 0.0045 16.4 0.0 0.033 13.6 0.0 2.1 2 0 0 2 2 2 1 Bacterial TniB protein AAA_18 PF13238.6 CRK16573.1 - 0.01 16.4 0.0 0.018 15.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 CRK16573.1 - 0.013 15.0 0.0 1.3 8.4 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein ResIII PF04851.15 CRK16573.1 - 0.017 15.1 0.0 0.082 12.9 0.0 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_7 PF12775.7 CRK16573.1 - 0.019 14.5 0.0 0.038 13.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 CRK16573.1 - 0.056 13.0 0.0 0.2 11.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 CRK16573.1 - 0.06 12.6 0.0 0.093 11.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.22 CRK16573.1 - 0.17 12.3 0.0 0.4 11.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Fungal_trans_2 PF11951.8 CRK16574.1 - 3.2e-08 32.8 0.1 1.6e-05 24.0 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK16574.1 - 2.8e-07 30.5 11.0 5.5e-07 29.6 11.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SR-25 PF10500.9 CRK16574.1 - 0.026 14.1 9.2 0.042 13.4 9.2 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RAP1 PF07218.11 CRK16574.1 - 1.3 7.3 4.0 1.7 6.8 4.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Thioredoxin_6 PF13848.6 CRK16575.1 - 1.4e-09 38.2 0.0 8.6e-08 32.3 0.0 2.3 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.20 CRK16575.1 - 0.00021 21.2 0.0 0.00055 19.9 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin 2OG-FeII_Oxy_3 PF13640.6 CRK16576.1 - 1.5e-10 41.8 0.0 2.6e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Zn_clus PF00172.18 CRK16577.1 - 1.2e-08 34.9 10.8 2.1e-08 34.1 10.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2770 PF10968.8 CRK16577.1 - 0.18 11.8 0.2 3.9 7.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2770) MFS_1 PF07690.16 CRK16578.1 - 4.1e-23 81.9 27.4 4.1e-23 81.9 27.4 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily TF_Otx PF03529.13 CRK16578.1 - 0.097 13.1 0.1 0.28 11.6 0.1 1.8 1 1 0 1 1 1 0 Otx1 transcription factor DUF3237 PF11578.8 CRK16579.1 - 1.4e-27 96.4 0.0 1.6e-27 96.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Amidase PF01425.21 CRK16580.1 - 2.1e-89 300.6 0.0 6.7e-89 298.9 0.0 1.7 1 1 0 1 1 1 1 Amidase NmrA PF05368.13 CRK16581.1 - 2e-16 60.2 0.4 2.6e-16 59.9 0.4 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 CRK16581.1 - 1.8e-13 50.8 0.3 4.3e-13 49.6 0.3 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 CRK16581.1 - 3.8e-06 26.6 0.1 0.00044 19.8 0.1 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CRK16581.1 - 6.6e-05 22.0 0.0 0.00011 21.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.17 CRK16581.1 - 0.00014 22.4 1.0 0.00035 21.1 0.5 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent GDP_Man_Dehyd PF16363.5 CRK16581.1 - 0.0039 16.6 0.1 0.22 10.9 0.0 2.2 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase KR PF08659.10 CRK16581.1 - 0.0093 15.9 0.1 0.015 15.2 0.1 1.4 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 CRK16581.1 - 0.093 11.8 0.6 0.85 8.7 0.1 2.0 2 0 0 2 2 2 0 RmlD substrate binding domain Semialdhyde_dh PF01118.24 CRK16581.1 - 0.12 12.8 0.4 0.23 11.9 0.4 1.6 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 CRK16581.1 - 0.15 12.2 2.0 0.17 12.0 0.6 1.8 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus TFR_dimer PF04253.15 CRK16582.1 - 2.8e-22 79.1 0.0 5.5e-22 78.1 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.22 CRK16582.1 - 1.1e-13 51.0 2.6 2.8e-12 46.5 2.7 2.9 2 1 0 2 2 2 1 PA domain Peptidase_M28 PF04389.17 CRK16582.1 - 1.2e-07 31.6 0.0 4.9e-06 26.4 0.0 2.2 1 1 0 1 1 1 1 Peptidase family M28 MFS_1 PF07690.16 CRK16583.1 - 2e-09 36.8 35.5 3.5e-08 32.8 12.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily PilX_N PF14341.6 CRK16583.1 - 0.082 12.9 0.8 0.21 11.6 0.0 2.1 2 0 0 2 2 2 0 PilX N-terminal zf-CSL PF05207.13 CRK16584.1 - 8.4e-23 79.9 0.8 1.1e-22 79.6 0.8 1.1 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.10 CRK16584.1 - 0.0022 18.0 0.3 0.0035 17.4 0.3 1.3 1 0 0 1 1 1 1 Zinc ribbon domain Prok-RING_1 PF14446.6 CRK16584.1 - 0.22 11.5 2.9 0.44 10.5 2.9 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 ABC_membrane_2 PF06472.15 CRK16585.1 - 2.6e-103 345.1 1.3 4.1e-103 344.5 1.3 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 CRK16585.1 - 1.5e-18 67.6 0.0 3.5e-18 66.4 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CRK16585.1 - 0.0003 20.7 0.0 0.00072 19.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CRK16585.1 - 0.011 16.3 0.0 0.11 13.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 CRK16585.1 - 0.067 12.9 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.19 CRK16585.1 - 0.077 12.4 0.3 0.27 10.7 0.0 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CRK16585.1 - 0.12 12.8 0.1 0.61 10.4 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Cloacin_immun PF03513.14 CRK16585.1 - 0.12 12.7 0.0 0.71 10.3 0.0 2.2 2 0 0 2 2 2 0 Cloacin immunity protein RuvB_N PF05496.12 CRK16585.1 - 0.15 11.8 0.0 0.51 10.1 0.0 1.9 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 CRK16585.1 - 0.15 11.4 0.1 0.63 9.4 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 CRK16585.1 - 0.16 11.9 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain HSP70 PF00012.20 CRK16586.1 - 2.5e-13 49.1 0.0 3.9e-11 41.9 0.0 2.1 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 CRK16586.1 - 0.00057 18.8 0.1 0.1 11.4 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Cupin_2 PF07883.11 CRK16588.1 - 1.6e-06 27.7 0.4 2.7e-06 27.0 0.4 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 CRK16588.1 - 1e-05 25.2 0.1 1.4e-05 24.7 0.1 1.2 1 0 0 1 1 1 1 Cupin Cupin_6 PF12852.7 CRK16588.1 - 0.003 17.3 0.0 0.0041 16.9 0.0 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 CRK16588.1 - 0.021 14.8 0.0 0.029 14.3 0.0 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain ARD PF03079.14 CRK16588.1 - 0.074 13.2 0.0 0.095 12.9 0.0 1.3 1 0 0 1 1 1 0 ARD/ARD' family 4HBT_3 PF13622.6 CRK16589.1 - 8.5e-34 117.9 0.3 2.6e-25 90.1 0.1 2.0 2 0 0 2 2 2 2 Thioesterase-like superfamily ComK PF06338.11 CRK16589.1 - 0.21 11.2 0.0 0.36 10.4 0.0 1.3 1 0 0 1 1 1 0 ComK protein AAA PF00004.29 CRK16590.1 - 1e-18 68.0 0.0 1.9e-18 67.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CRK16590.1 - 0.00019 21.8 0.0 0.0031 17.9 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 CRK16590.1 - 0.0017 18.2 0.0 0.0034 17.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF4637 PF15470.6 CRK16590.1 - 0.0086 15.8 2.7 0.016 15.0 2.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4637) AAA_22 PF13401.6 CRK16590.1 - 0.012 15.9 0.0 0.04 14.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 CRK16590.1 - 0.031 14.3 0.1 0.13 12.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AIM3 PF17096.5 CRK16590.1 - 0.032 15.2 3.4 0.073 14.0 3.4 1.5 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 AAA_17 PF13207.6 CRK16590.1 - 0.04 14.3 0.1 0.24 11.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 CRK16590.1 - 0.089 13.3 2.0 0.28 11.7 0.0 2.8 3 0 0 3 3 2 0 AAA domain AAA_11 PF13086.6 CRK16590.1 - 0.12 12.1 2.2 0.9 9.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 CRK16590.1 - 0.14 12.3 0.0 0.31 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma70_ner PF04546.13 CRK16590.1 - 0.14 12.0 6.4 0.31 10.9 6.4 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF1922 PF09082.10 CRK16590.1 - 0.18 12.1 1.0 0.45 10.8 1.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1922) DUF2457 PF10446.9 CRK16590.1 - 0.2 10.8 16.7 0.32 10.1 16.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) BSP_II PF05432.11 CRK16590.1 - 0.21 11.3 16.3 0.068 12.9 13.4 1.6 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) CNDH2_C PF16858.5 CRK16590.1 - 0.3 10.9 6.7 0.58 10.0 6.7 1.4 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term RXT2_N PF08595.11 CRK16590.1 - 0.39 10.7 7.3 0.83 9.7 7.3 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal GP24_25 PF17388.2 CRK16590.1 - 0.44 10.5 3.5 1.1 9.2 3.5 1.6 1 0 0 1 1 1 0 Tail assembly gene products 24 & 25 Nop14 PF04147.12 CRK16590.1 - 0.68 8.1 14.1 0.93 7.6 14.1 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 CRK16590.1 - 1.1 7.5 9.5 1.5 7.0 9.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Mg_chelatase PF01078.21 CRK16590.1 - 1.2 8.5 2.9 1.8 7.9 0.1 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI FAM176 PF14851.6 CRK16590.1 - 1.8 8.2 9.3 3.5 7.3 9.3 1.4 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.12 CRK16590.1 - 4.5 6.5 17.2 6.9 5.9 17.2 1.2 1 0 0 1 1 1 0 NOA36 protein TRAP_alpha PF03896.16 CRK16590.1 - 7.4 5.7 7.6 12 5.0 7.6 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit SDA1 PF05285.12 CRK16590.1 - 8.2 5.8 15.3 13 5.1 15.3 1.2 1 0 0 1 1 1 0 SDA1 Glyco_hydro_35 PF01301.19 CRK16592.1 - 5.9e-85 285.7 0.2 9.7e-85 284.9 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.9 CRK16592.1 - 3.8e-58 196.3 0.9 6e-58 195.6 0.9 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.6 CRK16592.1 - 4.1e-51 172.4 1.0 7.5e-31 107.1 0.0 2.9 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.6 CRK16592.1 - 1.6e-21 75.6 0.0 8.5e-21 73.3 0.0 2.3 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Cellulase PF00150.18 CRK16592.1 - 0.0024 17.3 0.0 0.0041 16.6 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyoxalase PF00903.25 CRK16593.1 - 0.0089 16.2 0.0 0.086 13.0 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily tRNA-synt_1 PF00133.22 CRK16594.1 - 1.4e-36 126.0 0.0 2e-27 95.7 0.0 3.4 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 CRK16594.1 - 4.8e-14 51.9 0.3 9.6e-09 34.5 0.0 2.9 3 0 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 CRK16594.1 - 2.2e-07 30.5 0.0 5.4e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Frataxin_Cyay PF01491.16 CRK16596.1 - 3.2e-36 123.7 0.0 4.1e-36 123.3 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain MFS_1 PF07690.16 CRK16598.1 - 7.9e-25 87.5 62.5 4.7e-23 81.7 37.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TauD PF02668.16 CRK16600.1 - 4.8e-41 141.3 0.4 7.2e-41 140.8 0.4 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family NOG1 PF06858.14 CRK16600.1 - 0.19 11.5 0.0 0.82 9.5 0.0 2.1 2 0 0 2 2 2 0 Nucleolar GTP-binding protein 1 (NOG1) Mac PF12464.8 CRK16602.1 - 1.3e-17 63.8 0.0 2.3e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.24 CRK16602.1 - 2.4e-12 46.1 12.2 5.6e-12 44.9 4.9 2.9 3 0 0 3 3 3 1 Bacterial transferase hexapeptide (six repeats) GST_N PF02798.20 CRK16602.1 - 7.2e-11 42.3 0.0 1.2e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Hexapep_2 PF14602.6 CRK16602.1 - 2.2e-10 40.1 10.7 6.4e-09 35.4 3.7 3.0 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase GST_N_3 PF13417.6 CRK16602.1 - 8.7e-09 35.7 0.0 1.7e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CRK16602.1 - 3.9e-06 27.1 0.0 7.1e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CRK16602.1 - 0.00041 20.5 0.0 0.00081 19.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CRK16602.1 - 0.0012 18.9 0.0 0.0027 17.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CRK16602.1 - 0.0042 17.3 0.0 0.0074 16.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Abhydrolase_4 PF08386.10 CRK16603.1 - 2e-17 63.2 0.0 7.8e-17 61.3 0.0 2.0 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_1 PF00561.20 CRK16603.1 - 1.2e-15 57.8 0.0 2.9e-12 46.8 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CRK16603.1 - 0.019 14.2 0.0 0.064 12.5 0.0 1.9 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF4219 PF13961.6 CRK16604.1 - 0.00013 21.5 0.2 0.0018 17.9 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4219) HTH_18 PF12833.7 CRK16605.1 - 0.053 13.8 0.0 0.16 12.2 0.0 1.8 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_AraC PF00165.23 CRK16605.1 - 0.091 12.9 0.2 6.2 7.1 0.0 2.8 3 0 0 3 3 3 0 Bacterial regulatory helix-turn-helix proteins, AraC family Menin PF05053.13 CRK16605.1 - 9.4 4.5 11.1 12 4.1 11.1 1.2 1 0 0 1 1 1 0 Menin GFO_IDH_MocA PF01408.22 CRK16606.1 - 5e-20 72.5 0.0 9.5e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold ABC_tran PF00005.27 CRK16607.1 - 5.4e-25 88.5 0.0 1e-24 87.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 CRK16607.1 - 1.2e-07 31.4 17.4 2.2e-07 30.5 17.4 1.4 1 0 0 1 1 1 1 ABC-2 type transporter AAA_16 PF13191.6 CRK16607.1 - 4.4e-05 23.9 0.1 5.9e-05 23.5 0.1 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 CRK16607.1 - 7.7e-05 22.3 0.1 0.00013 21.6 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.6 CRK16607.1 - 0.00011 22.1 0.1 0.41 10.4 0.2 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 CRK16607.1 - 0.00054 20.3 0.0 0.0009 19.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 CRK16607.1 - 0.00092 19.2 0.1 0.0014 18.6 0.1 1.2 1 0 0 1 1 1 1 RsgA GTPase T2SSE PF00437.20 CRK16607.1 - 0.0022 17.1 0.1 0.0032 16.6 0.1 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.6 CRK16607.1 - 0.0043 16.8 0.1 0.0077 16.0 0.1 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain NACHT PF05729.12 CRK16607.1 - 0.0057 16.6 0.1 0.0098 15.8 0.1 1.3 1 0 0 1 1 1 1 NACHT domain NTPase_1 PF03266.15 CRK16607.1 - 0.0094 15.9 0.2 0.019 14.9 0.2 1.5 1 1 0 1 1 1 1 NTPase cobW PF02492.19 CRK16607.1 - 0.01 15.4 0.1 0.015 14.9 0.1 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 CRK16607.1 - 0.015 15.0 0.1 0.022 14.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CRK16607.1 - 0.018 14.8 0.9 0.029 14.1 0.8 1.4 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 CRK16607.1 - 0.019 15.2 0.2 0.028 14.6 0.2 1.2 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 CRK16607.1 - 0.019 15.0 0.2 0.033 14.2 0.2 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase IstB_IS21 PF01695.17 CRK16607.1 - 0.032 14.0 0.0 0.052 13.3 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 CRK16607.1 - 0.035 14.5 0.0 0.063 13.7 0.0 1.4 1 0 0 1 1 1 0 RNA helicase MobB PF03205.14 CRK16607.1 - 0.038 13.9 0.1 0.059 13.3 0.1 1.2 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.6 CRK16607.1 - 0.054 14.1 0.1 0.087 13.4 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CRK16607.1 - 0.056 13.6 0.0 0.079 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 CRK16607.1 - 0.065 12.7 0.0 0.42 10.0 0.0 2.0 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain SRP54 PF00448.22 CRK16607.1 - 0.067 12.8 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_19 PF13245.6 CRK16607.1 - 0.08 13.3 0.3 0.17 12.2 0.3 1.6 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CRK16607.1 - 0.091 13.2 0.2 0.15 12.6 0.2 1.2 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 CRK16607.1 - 0.13 12.0 0.2 0.25 11.0 0.2 1.4 1 0 0 1 1 1 0 Cytidylate kinase AAA_5 PF07728.14 CRK16607.1 - 0.14 12.1 0.0 0.34 10.9 0.1 1.6 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 CRK16607.1 - 0.15 12.5 0.0 0.46 10.9 0.1 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 CRK16607.1 - 0.16 12.0 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 CRK16607.1 - 0.19 11.0 0.1 0.28 10.4 0.1 1.2 1 0 0 1 1 1 0 Septin ATP_bind_1 PF03029.17 CRK16607.1 - 0.2 11.4 0.2 0.3 10.8 0.2 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Rad17 PF03215.15 CRK16607.1 - 0.21 11.5 0.0 0.33 10.8 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain NB-ARC PF00931.22 CRK16607.1 - 0.21 10.7 1.5 0.74 8.9 0.1 2.0 1 1 1 2 2 2 0 NB-ARC domain ABC2_membrane_3 PF12698.7 CRK16607.1 - 0.46 9.5 11.9 0.63 9.1 11.9 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DEC-1_N PF04625.13 CRK16608.1 - 3 6.7 4.7 2.9 6.8 4.7 1.0 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region ABC2_membrane PF01061.24 CRK16610.1 - 7.3e-46 156.2 56.0 5.1e-25 88.1 32.7 2.2 1 1 1 2 2 2 2 ABC-2 type transporter ABC2_membrane_3 PF12698.7 CRK16610.1 - 0.00036 19.8 14.8 0.00036 19.8 14.8 3.2 1 1 2 3 3 3 1 ABC-2 family transporter protein PcrB PF01884.17 CRK16610.1 - 0.0059 16.1 1.6 2.4 7.6 0.1 2.3 2 0 0 2 2 2 2 PcrB family DUF2235 PF09994.9 CRK16611.1 - 1.2e-35 123.2 0.0 1.7e-35 122.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF711 PF05167.12 CRK16612.1 - 4.2e-05 22.6 0.7 0.14 11.1 0.0 2.2 2 0 0 2 2 2 2 Uncharacterised ACR (DUF711) SUIM_assoc PF16619.5 CRK16612.1 - 0.0077 16.3 15.9 0.021 14.9 7.4 2.9 2 0 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 RuBisCO_large_N PF02788.16 CRK16612.1 - 0.025 14.7 2.0 3.7 7.7 0.2 2.3 2 0 0 2 2 2 0 Ribulose bisphosphate carboxylase large chain, N-terminal domain JmjC PF02373.22 CRK16612.1 - 0.027 14.9 2.4 2.3 8.7 0.4 2.3 2 0 0 2 2 2 0 JmjC domain, hydroxylase TFIIA PF03153.13 CRK16612.1 - 0.094 12.7 9.4 0.77 9.7 2.9 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CCDC53 PF10152.9 CRK16612.1 - 0.65 10.4 6.8 3.9 7.9 1.0 2.6 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Spt20 PF12090.8 CRK16612.1 - 2.3 7.8 16.8 1.9 8.0 7.1 2.2 2 0 0 2 2 2 0 Spt20 family Glycos_transf_1 PF00534.20 CRK16613.1 - 4e-29 101.4 0.0 6.8e-29 100.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CRK16613.1 - 1.1e-26 93.8 0.1 2e-26 93.0 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 CRK16613.1 - 1.2e-20 74.5 1.1 1.2e-20 74.5 1.1 2.8 3 1 0 3 3 3 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 CRK16613.1 - 1.8e-15 57.3 1.0 9.1e-14 51.8 0.2 2.3 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 CRK16613.1 - 1.7e-10 41.2 0.0 4.3e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 MFS_1 PF07690.16 CRK16614.1 - 2.3e-18 66.3 38.5 3.2e-17 62.5 19.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans_2 PF11951.8 CRK16614.1 - 2.2e-09 36.6 5.6 2.1e-07 30.1 1.5 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Methyltransf_23 PF13489.6 CRK16615.1 - 2e-21 76.6 0.0 3.4e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK16615.1 - 1.5e-14 54.4 0.0 4.2e-14 53.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CRK16615.1 - 4.1e-13 49.8 0.0 1e-12 48.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK16615.1 - 3.9e-10 40.4 0.0 2.4e-09 37.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK16615.1 - 1.1e-07 31.8 0.0 5.3e-07 29.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CRK16615.1 - 5.2e-05 22.7 0.0 0.0019 17.6 0.0 2.7 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 CRK16615.1 - 0.00064 19.1 0.0 0.0015 17.9 0.0 1.6 2 0 0 2 2 2 1 O-methyltransferase domain MTS PF05175.14 CRK16615.1 - 0.0008 19.0 0.0 0.0015 18.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 CRK16615.1 - 0.0011 18.5 0.0 0.0017 17.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 CRK16615.1 - 0.0031 17.3 0.0 0.0048 16.7 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_4 PF02390.17 CRK16615.1 - 0.055 12.9 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase DUF938 PF06080.12 CRK16615.1 - 0.099 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) FtsJ PF01728.19 CRK16615.1 - 0.16 12.1 0.0 0.34 11.0 0.0 1.5 2 0 0 2 2 2 0 FtsJ-like methyltransferase CAP_N PF01213.19 CRK16615.1 - 1.4 8.4 4.0 1.8 8.0 4.0 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal MFS_1 PF07690.16 CRK16616.1 - 7.5e-34 117.2 25.9 7.5e-34 117.2 25.9 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Corona_M PF01635.18 CRK16616.1 - 0.0058 16.0 2.3 1.2 8.4 0.1 2.5 2 0 0 2 2 2 2 Coronavirus M matrix/glycoprotein Git3 PF11710.8 CRK16616.1 - 0.43 10.3 5.6 0.08 12.7 0.5 2.4 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 RGS PF00615.19 CRK16617.1 - 6.4e-05 23.2 0.0 0.00022 21.5 0.0 1.8 1 1 0 1 1 1 1 Regulator of G protein signaling domain Peptidase_M50 PF02163.22 CRK16617.1 - 0.088 12.1 0.0 0.1 11.8 0.0 1.1 1 0 0 1 1 1 0 Peptidase family M50 RGS PF00615.19 CRK16618.1 - 0.00011 22.4 0.0 0.00043 20.5 0.0 1.9 1 1 0 1 1 1 1 Regulator of G protein signaling domain Rap1_C PF11626.8 CRK16618.1 - 0.043 13.9 0.9 0.65 10.1 1.2 2.7 2 1 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF4407 PF14362.6 CRK16618.1 - 3.5 6.9 18.6 9.4 5.5 18.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3584 PF12128.8 CRK16618.1 - 6.6 4.1 24.7 9.4 3.6 24.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ABC_tran PF00005.27 CRK16621.1 - 1.3e-20 74.3 0.0 2.3e-20 73.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_trans_N PF14510.6 CRK16621.1 - 5.4e-10 39.8 0.0 9.9e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 CRK16621.1 - 0.029 14.8 0.0 0.057 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 CRK16621.1 - 0.047 13.8 0.0 0.42 10.7 0.0 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_22 PF13401.6 CRK16621.1 - 0.086 13.1 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 CRK16621.1 - 0.19 11.6 0.0 0.28 11.1 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ABC2_membrane PF01061.24 CRK16622.1 - 3.7e-119 395.7 115.6 1.2e-39 135.9 23.1 6.9 7 0 0 7 7 7 5 ABC-2 type transporter PDR_CDR PF06422.12 CRK16622.1 - 3.1e-53 177.6 8.4 1.3e-24 85.9 0.0 4.4 4 0 0 4 4 3 3 CDR ABC transporter ABC_tran PF00005.27 CRK16622.1 - 1.4e-46 158.4 0.0 4e-16 59.8 0.0 4.5 4 0 0 4 4 4 4 ABC transporter RsgA_GTPase PF03193.16 CRK16622.1 - 3.4e-13 49.9 0.3 0.00014 21.8 0.0 3.3 3 0 0 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 CRK16622.1 - 1.6e-12 48.1 1.0 0.0018 18.7 0.2 3.7 3 0 0 3 3 3 3 AAA ATPase domain AAA_33 PF13671.6 CRK16622.1 - 3.3e-11 43.5 0.2 0.0059 16.8 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_21 PF13304.6 CRK16622.1 - 2.5e-09 37.4 0.6 0.15 11.8 0.1 4.3 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC_trans_N PF14510.6 CRK16622.1 - 2.6e-09 37.6 0.0 8.9e-09 35.8 0.0 2.0 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_28 PF13521.6 CRK16622.1 - 3.1e-09 37.3 1.1 0.032 14.5 0.1 3.6 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 CRK16622.1 - 1.1e-08 35.5 4.1 0.14 12.4 0.1 4.4 6 0 0 6 6 3 3 AAA domain MMR_HSR1 PF01926.23 CRK16622.1 - 1.7e-08 34.5 1.7 0.15 12.1 0.1 3.4 3 0 0 3 3 3 2 50S ribosome-binding GTPase cobW PF02492.19 CRK16622.1 - 1.1e-07 31.6 6.4 0.015 14.9 0.4 3.3 3 0 0 3 3 3 2 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 CRK16622.1 - 1.1e-07 32.5 0.0 0.32 11.6 0.0 3.7 3 0 0 3 3 3 2 AAA domain AAA_24 PF13479.6 CRK16622.1 - 1.5e-06 28.1 0.1 0.37 10.5 0.0 3.9 5 0 0 5 5 3 2 AAA domain AAA_17 PF13207.6 CRK16622.1 - 2.4e-06 28.0 0.4 0.27 11.7 0.0 3.4 3 0 0 3 3 3 2 AAA domain NACHT PF05729.12 CRK16622.1 - 3.1e-06 27.2 1.9 0.46 10.4 0.2 3.6 3 0 0 3 3 3 2 NACHT domain ABC2_membrane_3 PF12698.7 CRK16622.1 - 4.3e-06 26.1 38.1 1.5e-05 24.3 11.1 5.0 6 0 0 6 6 5 3 ABC-2 family transporter protein AAA_29 PF13555.6 CRK16622.1 - 8.2e-06 25.5 4.9 0.74 9.6 0.2 3.7 3 0 0 3 3 3 2 P-loop containing region of AAA domain SMC_N PF02463.19 CRK16622.1 - 2.2e-05 24.0 0.4 0.45 9.9 0.0 3.7 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 CRK16622.1 - 2.8e-05 23.8 2.5 1.1 8.8 0.0 4.0 3 1 0 3 3 3 2 AAA domain TsaE PF02367.17 CRK16622.1 - 4.4e-05 23.5 2.0 0.42 10.6 0.2 3.1 4 0 0 4 4 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Septin PF00735.18 CRK16622.1 - 4.5e-05 22.9 0.2 1.5 8.0 0.1 3.1 3 0 0 3 3 3 2 Septin PduV-EutP PF10662.9 CRK16622.1 - 0.00043 20.1 3.3 1.5 8.6 0.2 3.4 3 0 0 3 3 3 2 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.6 CRK16622.1 - 0.00068 20.0 4.1 6.8 7.0 0.3 3.6 3 0 0 3 3 3 0 AAA domain FeoB_N PF02421.18 CRK16622.1 - 0.00093 18.8 0.6 1.8 8.1 0.1 2.9 3 0 0 3 3 3 2 Ferrous iron transport protein B Zeta_toxin PF06414.12 CRK16622.1 - 0.0021 17.3 2.9 1.6 8.0 0.2 2.9 3 0 0 3 3 3 2 Zeta toxin RNA_helicase PF00910.22 CRK16622.1 - 0.0026 18.1 0.1 19 5.7 0.0 3.4 3 0 0 3 3 3 0 RNA helicase PRK PF00485.18 CRK16622.1 - 0.0029 17.4 0.4 2.7 7.7 0.0 2.4 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family AAA_14 PF13173.6 CRK16622.1 - 0.0036 17.3 0.7 5.9 6.9 0.1 3.2 3 0 0 3 3 3 0 AAA domain ATPase_2 PF01637.18 CRK16622.1 - 0.0037 17.2 0.0 2.9 7.8 0.0 3.2 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_30 PF13604.6 CRK16622.1 - 0.0041 16.8 6.3 2.8 7.6 0.2 3.7 4 0 0 4 4 3 2 AAA domain Roc PF08477.13 CRK16622.1 - 0.0067 16.6 1.0 7.5 6.8 0.1 3.0 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA PF00004.29 CRK16622.1 - 0.0081 16.6 2.0 14 6.2 0.0 3.8 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.14 CRK16622.1 - 0.009 15.9 0.8 5.1 7.0 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Ploopntkinase3 PF18751.1 CRK16622.1 - 0.0099 15.8 0.3 37 4.2 0.0 3.3 3 0 0 3 3 3 0 P-loop Nucleotide Kinase3 Dynamin_N PF00350.23 CRK16622.1 - 0.012 15.7 1.7 5.2 7.1 0.1 2.7 2 0 0 2 2 2 0 Dynamin family NB-ARC PF00931.22 CRK16622.1 - 0.02 14.1 2.9 11 5.1 0.1 3.1 3 0 0 3 3 3 0 NB-ARC domain SRP54 PF00448.22 CRK16622.1 - 0.027 14.1 4.2 2.6 7.7 0.3 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Rad17 PF03215.15 CRK16622.1 - 0.028 14.4 0.0 23 4.9 0.0 3.2 3 0 0 3 3 3 0 Rad17 P-loop domain FtsK_SpoIIIE PF01580.18 CRK16622.1 - 0.03 13.7 4.4 11 5.3 0.0 3.4 3 0 0 3 3 3 0 FtsK/SpoIIIE family NTPase_1 PF03266.15 CRK16622.1 - 0.042 13.8 0.4 42 4.0 0.1 4.0 5 0 0 5 5 4 0 NTPase dNK PF01712.19 CRK16622.1 - 0.045 13.6 1.2 9.6 6.0 0.1 2.8 3 0 0 3 3 3 0 Deoxynucleoside kinase AAA_23 PF13476.6 CRK16622.1 - 0.058 13.9 1.2 13 6.2 0.1 2.3 2 0 0 2 2 2 0 AAA domain CoaE PF01121.20 CRK16622.1 - 0.064 12.9 3.0 4.9 6.8 0.2 2.4 2 0 0 2 2 2 0 Dephospho-CoA kinase SbcCD_C PF13558.6 CRK16622.1 - 0.1 12.9 0.0 39 4.6 0.0 3.1 3 0 0 3 3 2 0 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.14 CRK16622.1 - 0.11 12.5 0.7 79 3.2 0.1 3.8 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) Arf PF00025.21 CRK16622.1 - 0.13 11.7 0.5 25 4.3 0.0 3.0 3 0 0 3 3 3 0 ADP-ribosylation factor family T2SSE PF00437.20 CRK16622.1 - 0.17 10.9 1.2 23 4.0 0.0 2.8 3 0 0 3 3 3 0 Type II/IV secretion system protein IstB_IS21 PF01695.17 CRK16622.1 - 0.24 11.1 0.5 39 3.9 0.0 2.9 3 0 0 3 3 2 0 IstB-like ATP binding protein APS_kinase PF01583.20 CRK16622.1 - 0.24 11.3 0.4 33 4.3 0.0 2.9 2 0 0 2 2 2 0 Adenylylsulphate kinase Pox_A32 PF04665.12 CRK16622.1 - 0.25 10.8 0.2 27 4.1 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_13 PF13166.6 CRK16622.1 - 0.26 9.9 3.7 22 3.5 0.0 3.6 4 0 0 4 4 4 0 AAA domain SRPRB PF09439.10 CRK16622.1 - 0.28 10.6 0.4 33 3.9 0.0 2.8 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 CRK16622.1 - 0.37 10.3 2.3 23 4.4 0.1 2.7 3 0 0 3 3 2 0 P-loop containing dynein motor region Viral_helicase1 PF01443.18 CRK16622.1 - 0.4 10.4 3.9 24 4.6 0.0 3.6 4 0 0 4 4 3 0 Viral (Superfamily 1) RNA helicase CbiA PF01656.23 CRK16622.1 - 0.51 10.4 2.1 27 4.8 0.2 2.5 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain MeaB PF03308.16 CRK16622.1 - 1.3 8.0 5.9 19 4.1 0.2 3.4 4 0 0 4 4 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF4396 PF14342.6 CRK16623.1 - 8.7e-45 152.5 4.6 8.9e-45 152.5 3.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4396) Pyridoxal_deC PF00282.19 CRK16623.1 - 0.0066 15.2 0.0 0.011 14.5 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain AMP-binding PF00501.28 CRK16624.1 - 6.6e-53 179.8 0.1 5.5e-52 176.8 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.12 CRK16624.1 - 2e-41 141.9 0.0 5.4e-41 140.5 0.0 1.8 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 CRK16624.1 - 2.9e-08 33.5 0.0 1e-07 31.6 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 CRK16624.1 - 0.00059 20.1 0.3 0.0021 18.4 0.1 2.1 2 0 0 2 2 2 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 CRK16624.1 - 0.0043 16.1 0.0 0.039 13.0 0.0 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 CRK16624.1 - 0.081 12.8 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 NAD(P)H-binding Sugar_tr PF00083.24 CRK16625.1 - 5.8e-80 269.4 7.1 6.6e-80 269.2 7.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK16625.1 - 5.6e-15 55.1 10.9 7.4e-15 54.7 10.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2530 PF10745.9 CRK16625.1 - 1.3 9.3 6.4 0.2 11.9 1.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) EBP PF05241.12 CRK16626.1 - 1.9e-53 180.6 7.1 2.3e-53 180.3 7.1 1.1 1 0 0 1 1 1 1 Emopamil binding protein MFS_1 PF07690.16 CRK16628.1 - 1.1e-36 126.5 41.4 1.1e-36 126.5 41.4 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 CRK16628.1 - 8.8e-17 60.7 9.7 8.8e-17 60.7 9.7 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Helicase_C PF00271.31 CRK16629.1 - 0.0007 19.9 0.0 0.001 19.4 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Peptidase_M15_4 PF13539.6 CRK16630.1 - 0.024 15.2 0.1 0.034 14.6 0.1 1.3 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase MRP-S27 PF10037.9 CRK16630.1 - 0.19 10.6 0.0 0.19 10.5 0.0 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 UDPGT PF00201.18 CRK16631.1 - 4.3e-17 62.1 0.0 1.4e-16 60.4 0.0 1.8 2 1 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_transf_28 PF03033.20 CRK16631.1 - 0.00035 20.6 0.0 0.00068 19.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Glyco_tran_28_C PF04101.16 CRK16631.1 - 0.001 19.1 0.0 0.0018 18.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.6 CRK16631.1 - 0.0036 16.6 0.7 0.17 11.1 0.0 2.7 2 1 0 2 2 2 1 Glycosyl transferase family 1 Glyco_transf_4 PF13439.6 CRK16631.1 - 0.029 14.3 0.1 0.11 12.5 0.1 2.0 1 0 0 1 1 1 0 Glycosyltransferase Family 4 MFS_1 PF07690.16 CRK16632.1 - 6.1e-11 41.8 45.8 1.2e-10 40.9 41.0 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily UcrQ PF02939.16 CRK16632.1 - 0.081 12.9 0.3 21 5.1 0.1 2.8 2 0 0 2 2 2 0 UcrQ family TetR_C_34 PF17929.1 CRK16632.1 - 0.14 12.3 0.0 0.43 10.7 0.0 1.8 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain NAD_binding_10 PF13460.6 CRK16633.1 - 4.9e-06 26.6 0.0 6.3e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 CRK16633.1 - 0.018 14.2 0.0 0.034 13.3 0.0 1.4 1 1 0 1 1 1 0 Male sterility protein Epimerase PF01370.21 CRK16633.1 - 0.057 12.9 0.0 0.085 12.3 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short PF00106.25 CRK16635.1 - 1.9e-39 135.2 0.0 2.4e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK16635.1 - 2.1e-22 79.8 0.0 2.6e-22 79.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK16635.1 - 3.5e-07 30.3 0.1 6.5e-07 29.4 0.1 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 CRK16635.1 - 1e-05 25.2 0.0 1.5e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 CRK16635.1 - 0.0001 22.8 0.2 0.00029 21.3 0.1 1.8 2 0 0 2 2 1 1 NADP oxidoreductase coenzyme F420-dependent GDP_Man_Dehyd PF16363.5 CRK16635.1 - 0.00024 20.6 0.0 0.00031 20.2 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 CRK16635.1 - 0.0016 17.6 0.1 0.0065 15.6 0.1 1.9 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 CRK16635.1 - 0.0019 18.2 0.0 0.0035 17.4 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 CRK16635.1 - 0.0022 18.3 0.0 0.004 17.4 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 CRK16635.1 - 0.0037 17.2 0.1 0.024 14.5 0.0 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 CRK16635.1 - 0.052 13.5 0.0 0.09 12.8 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase MFS_1 PF07690.16 CRK16636.1 - 5.7e-25 88.0 30.0 3.9e-24 85.2 27.3 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Shikimate_dh_N PF08501.11 CRK16636.1 - 3.7e-21 75.2 0.0 9e-21 73.9 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain DHquinase_I PF01487.15 CRK16636.1 - 9.8e-21 75.0 0.0 1.5e-20 74.4 0.0 1.2 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 CRK16636.1 - 1.2e-10 41.7 0.1 2.4e-10 40.7 0.1 1.4 1 0 0 1 1 1 1 Shikimate kinase Shikimate_DH PF01488.20 CRK16636.1 - 2.9e-06 27.4 0.0 5.8e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_25 PF13481.6 CRK16636.1 - 0.035 13.7 0.0 0.072 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CRK16636.1 - 0.045 14.1 0.3 0.33 11.3 0.1 2.4 3 0 0 3 3 3 0 AAA ATPase domain F420_oxidored PF03807.17 CRK16636.1 - 0.11 13.0 0.0 0.3 11.7 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Phage_holin_3_6 PF07332.11 CRK16636.1 - 0.12 12.4 3.5 5.7 7.0 0.0 3.7 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Sacchrp_dh_NADP PF03435.18 CRK16636.1 - 0.12 12.6 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain LapA_dom PF06305.11 CRK16636.1 - 0.82 9.5 3.0 1.8 8.4 0.1 2.9 1 1 1 2 2 2 0 Lipopolysaccharide assembly protein A domain Sugar_tr PF00083.24 CRK16637.1 - 2.6e-134 448.5 22.3 3e-134 448.3 22.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK16637.1 - 7.2e-21 74.5 40.7 3.1e-18 65.8 14.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Shikimate_dh_N PF08501.11 CRK16638.1 - 2e-22 79.2 0.0 4.1e-22 78.2 0.0 1.6 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 CRK16638.1 - 1.1e-05 25.1 0.2 2.5e-05 23.9 0.2 1.6 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 CRK16638.1 - 0.034 14.2 0.0 0.054 13.6 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GFO_IDH_MocA PF01408.22 CRK16638.1 - 0.072 13.9 0.1 0.14 13.0 0.1 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold AP_endonuc_2 PF01261.24 CRK16639.1 - 1.1e-30 106.6 1.0 1.8e-30 105.9 0.5 1.5 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel DHquinase_II PF01220.19 CRK16640.1 - 1.7e-46 157.4 0.1 6.1e-46 155.5 0.1 1.9 1 1 0 1 1 1 1 Dehydroquinase class II Inositol_P PF00459.25 CRK16641.1 - 4e-70 236.4 0.0 4.8e-70 236.2 0.0 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family LysM PF01476.20 CRK16642.1 - 7.9e-32 109.1 0.0 4.8e-05 23.3 0.0 6.5 6 0 0 6 6 6 6 LysM domain Plasmod_Pvs28 PF06247.11 CRK16642.1 - 0.0017 18.6 7.0 1.5 9.2 0.1 4.3 4 0 0 4 4 4 2 Pvs28 EGF domain HTH_23 PF13384.6 CRK16642.1 - 0.02 14.7 0.0 57 3.7 0.0 3.7 4 0 0 4 4 4 0 Homeodomain-like domain LRV_FeS PF05484.11 CRK16642.1 - 0.07 13.1 0.0 10 6.2 0.0 4.1 5 0 0 5 5 5 0 LRV protein FeS4 cluster DTC PF18102.1 CRK16642.1 - 0.087 13.0 0.0 1.8 8.7 0.0 2.7 2 0 0 2 2 2 0 Deltex C-terminal domain Pkinase PF00069.25 CRK16643.1 - 8.9e-22 77.7 0.0 2.9e-21 76.0 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK16643.1 - 2.3e-12 46.8 0.0 3.4e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CRK16643.1 - 0.00062 19.2 0.0 0.00093 18.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CRK16643.1 - 0.0038 16.1 0.0 0.0056 15.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pox_ser-thr_kin PF05445.11 CRK16643.1 - 0.26 10.2 0.0 0.4 9.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Fungal_trans_2 PF11951.8 CRK16644.1 - 1e-06 27.9 1.0 1.4e-06 27.4 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK16644.1 - 1.3e-06 28.4 7.8 2.3e-06 27.6 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 CRK16645.1 - 6.2e-67 226.4 14.9 7.5e-67 226.1 14.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK16645.1 - 6.4e-17 61.5 16.5 8.8e-17 61.1 16.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 CRK16645.1 - 0.00046 19.2 4.3 0.00046 19.2 4.3 2.1 2 0 0 2 2 2 2 MFS_1 like family MIOX PF05153.15 CRK16646.1 - 1.7e-114 381.6 0.0 2.1e-114 381.3 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol oxygenase HDOD PF08668.12 CRK16646.1 - 0.037 13.5 0.0 0.1 12.0 0.0 1.7 1 1 1 2 2 2 0 HDOD domain HD PF01966.22 CRK16646.1 - 0.043 14.0 0.0 1 9.6 0.0 2.2 2 0 0 2 2 2 0 HD domain Sec7_N PF12783.7 CRK16647.1 - 8.3e-37 126.5 1.3 8.3e-37 126.5 1.3 3.2 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 CRK16647.1 - 8.4e-35 118.5 11.6 3.9e-33 113.1 0.2 5.8 7 0 0 7 7 7 2 Domain of unknown function (DUF1981) Sec7 PF01369.20 CRK16647.1 - 3.5e-30 105.0 3.1 3.2e-29 101.9 0.3 3.1 3 0 0 3 3 3 1 Sec7 domain DCB PF16213.5 CRK16647.1 - 2.1e-22 79.7 1.3 1.9e-21 76.6 0.0 2.9 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 TetR_C_29 PF17938.1 CRK16647.1 - 0.19 11.8 0.7 0.98 9.5 0.0 2.6 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain HpcH_HpaI PF03328.14 CRK16649.1 - 5.1e-33 114.1 0.1 6.5e-33 113.7 0.1 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family CoA_binding_2 PF13380.6 CRK16649.1 - 0.081 13.4 0.5 1.6 9.2 0.0 2.5 2 1 0 2 2 2 0 CoA binding domain 2-oxoacid_dh PF00198.23 CRK16650.1 - 1.1e-73 247.5 0.0 1.8e-73 246.9 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 CRK16650.1 - 5.4e-18 64.6 1.1 1.2e-17 63.5 1.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 CRK16650.1 - 2e-09 37.6 1.6 7e-09 35.9 1.6 2.0 1 0 0 1 1 1 1 e3 binding domain DUF3614 PF12267.8 CRK16650.1 - 0.011 16.2 1.7 0.068 13.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3614) RNA_pol_3_Rpc31 PF11705.8 CRK16652.1 - 3.7e-59 200.7 3.5 5e-59 200.3 3.5 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Nucleoporin_FG PF13634.6 CRK16653.1 - 1.6e-10 41.7 79.3 0.00047 20.9 42.2 3.4 1 1 2 3 3 3 3 Nucleoporin FG repeat region PMEI PF04043.15 CRK16653.1 - 0.12 12.7 0.4 0.3 11.4 0.1 1.8 2 0 0 2 2 2 0 Plant invertase/pectin methylesterase inhibitor DUF241 PF03087.14 CRK16653.1 - 0.13 12.0 0.4 0.27 11.0 0.4 1.4 1 1 0 1 1 1 0 Arabidopsis protein of unknown function DUF1640 PF07798.11 CRK16653.1 - 0.6 10.1 3.1 0.21 11.6 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) Tup_N PF08581.10 CRK16653.1 - 0.73 10.2 3.5 0.65 10.3 0.1 2.5 3 0 0 3 3 3 0 Tup N-terminal FAM184 PF15665.5 CRK16653.1 - 0.9 9.3 5.2 12 5.6 5.2 2.3 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B Fip1 PF05182.13 CRK16654.1 - 3.2e-18 65.0 0.4 5.6e-18 64.2 0.4 1.4 1 0 0 1 1 1 1 Fip1 motif FtsX PF02687.21 CRK16656.1 - 0.095 13.2 0.2 0.19 12.2 0.2 1.4 1 0 0 1 1 1 0 FtsX-like permease family Pyr_redox_2 PF07992.14 CRK16657.1 - 1.8e-12 47.1 0.0 6.6e-09 35.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CRK16657.1 - 1.3e-05 25.3 0.0 3.3e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 CRK16657.1 - 1.3e-05 23.8 0.0 0.00047 18.7 0.0 2.5 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 CRK16657.1 - 2.3e-05 23.8 0.0 0.013 14.8 0.0 3.3 3 1 1 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CRK16657.1 - 3.7e-05 23.0 0.1 0.19 10.8 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 CRK16657.1 - 6.7e-05 22.9 0.0 0.002 18.1 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 CRK16657.1 - 0.0061 16.2 0.0 2.1 7.9 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase LBR_tudor PF09465.10 CRK16657.1 - 0.015 15.1 0.1 0.055 13.3 0.1 2.0 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain HI0933_like PF03486.14 CRK16657.1 - 0.06 12.0 0.0 0.18 10.5 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.24 CRK16657.1 - 0.068 12.2 0.0 0.19 10.8 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.17 CRK16657.1 - 0.13 11.5 0.0 1.2 8.3 0.0 2.1 2 0 0 2 2 2 0 Thi4 family Glyco_hydro_61 PF03443.14 CRK16658.1 - 9.8e-48 162.8 0.0 1.1e-47 162.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 adh_short PF00106.25 CRK16660.1 - 6e-09 35.6 0.0 0.00046 19.7 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CRK16660.1 - 8.7e-06 25.5 0.0 0.0002 21.0 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK16660.1 - 0.00075 19.5 0.0 0.0013 18.7 0.0 1.3 1 0 0 1 1 1 1 KR domain fn3_2 PF16893.5 CRK16661.1 - 7.7e-39 131.7 0.0 1.2e-38 131.1 0.0 1.3 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 CRK16661.1 - 4.7e-23 80.9 0.8 8.4e-23 80.1 0.8 1.4 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus PTCB-BRCT PF12738.7 CRK16661.1 - 1.7e-11 43.9 0.0 2.9e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 CRK16661.1 - 5.7e-10 39.4 0.0 9.5e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 CRK16661.1 - 1.5e-05 25.3 0.0 2.8e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain SUIM_assoc PF16619.5 CRK16661.1 - 0.00033 20.6 0.8 0.001 19.1 0.8 1.8 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 fn3 PF00041.21 CRK16661.1 - 0.0015 18.9 0.0 0.0054 17.0 0.0 2.0 1 1 0 1 1 1 1 Fibronectin type III domain DUF3006 PF11213.8 CRK16661.1 - 0.005 17.0 0.0 0.013 15.7 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) TFIIA PF03153.13 CRK16661.1 - 0.058 13.4 15.7 0.085 12.8 15.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nucleo_P87 PF07267.11 CRK16661.1 - 0.44 9.4 1.4 0.64 8.8 1.4 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 NOA36 PF06524.12 CRK16661.1 - 1.2 8.4 4.9 1.8 7.8 4.9 1.3 1 0 0 1 1 1 0 NOA36 protein NACHT PF05729.12 CRK16662.1 - 2.2e-07 31.0 0.2 0.0032 17.4 0.0 2.8 2 0 0 2 2 2 2 NACHT domain AAA_16 PF13191.6 CRK16662.1 - 5.2e-06 27.0 4.4 1.8e-05 25.2 0.1 3.3 3 1 0 3 3 3 1 AAA ATPase domain DUF676 PF05057.14 CRK16662.1 - 0.0026 17.3 0.1 0.0048 16.4 0.1 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) ABC_tran PF00005.27 CRK16662.1 - 0.0084 16.6 0.0 0.024 15.1 0.0 1.8 1 1 0 1 1 1 1 ABC transporter RNA_helicase PF00910.22 CRK16662.1 - 0.015 15.6 0.0 0.036 14.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.6 CRK16662.1 - 0.016 15.5 0.0 0.062 13.6 0.0 2.1 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 CRK16662.1 - 0.016 14.4 0.0 0.03 13.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Syntaxin-6_N PF09177.11 CRK16662.1 - 0.02 15.5 0.1 0.22 12.1 0.0 2.7 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Ank_4 PF13637.6 CRK16662.1 - 0.021 15.4 0.3 3.2 8.4 0.0 3.3 4 0 0 4 4 2 0 Ankyrin repeats (many copies) Ank PF00023.30 CRK16662.1 - 0.026 15.0 0.1 0.3 11.6 0.0 3.0 2 0 0 2 2 1 0 Ankyrin repeat AAA_33 PF13671.6 CRK16662.1 - 0.046 13.9 0.3 0.21 11.8 0.1 2.2 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 CRK16662.1 - 0.047 14.2 0.0 0.13 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CRK16662.1 - 0.062 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 CRK16662.1 - 0.072 13.0 0.0 4.1 7.3 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase Ank_5 PF13857.6 CRK16662.1 - 0.13 12.6 0.0 0.68 10.3 0.0 2.3 1 0 0 1 1 1 0 Ankyrin repeats (many copies) AAA PF00004.29 CRK16662.1 - 0.17 12.3 0.0 1.1 9.7 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PGAP1 PF07819.13 CRK16662.1 - 0.2 11.4 0.1 0.48 10.1 0.1 1.6 1 0 0 1 1 1 0 PGAP1-like protein eIF-1a PF01176.19 CRK16663.1 - 3.7e-20 71.5 0.0 5.4e-20 71.0 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 WH1 PF00568.23 CRK16664.1 - 1.1e-26 92.9 0.1 1.5e-26 92.5 0.1 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.20 CRK16664.1 - 0.00038 20.2 0.5 0.0022 17.8 1.2 1.9 2 0 0 2 2 2 1 WH2 motif DCP1 PF06058.13 CRK16664.1 - 0.11 12.4 0.1 0.18 11.8 0.1 1.3 1 0 0 1 1 1 0 Dcp1-like decapping family PBP1_TM PF14812.6 CRK16667.1 - 0.27 11.7 6.5 0.3 11.5 6.5 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal WH1 PF00568.23 CRK16668.1 - 1.2e-26 92.8 0.1 1.6e-26 92.4 0.1 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.20 CRK16668.1 - 0.00039 20.2 0.3 0.00083 19.1 0.3 1.5 1 0 0 1 1 1 1 WH2 motif DCP1 PF06058.13 CRK16668.1 - 0.12 12.3 0.1 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 Dcp1-like decapping family HhH-GPD PF00730.25 CRK16671.1 - 8.3e-07 29.4 0.0 1.8e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DNA_methylase PF00145.17 CRK16672.1 - 9.9e-35 120.4 0.0 2e-25 89.9 0.0 2.2 1 1 0 2 2 2 2 C-5 cytosine-specific DNA methylase Phage_fiber_C PF06820.12 CRK16672.1 - 0.15 12.4 0.0 0.3 11.5 0.0 1.5 1 0 0 1 1 1 0 Putative prophage tail fibre C-terminus Pectinesterase PF01095.19 CRK16673.1 - 2.9e-10 39.4 0.0 3.6e-10 39.1 0.0 1.0 1 0 0 1 1 1 1 Pectinesterase Pec_lyase_C PF00544.19 CRK16674.1 - 1.6e-12 47.5 5.3 9.1e-11 41.7 5.3 2.2 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 CRK16674.1 - 2.7e-06 27.3 5.6 3.6e-05 23.7 5.5 2.2 1 1 0 1 1 1 1 Right handed beta helix region Shigella_OspC PF06128.11 CRK16675.1 - 0.15 11.8 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 Shigella flexneri OspC protein Aspzincin_M35 PF14521.6 CRK16676.1 - 0.00011 22.8 0.0 0.00024 21.7 0.0 1.6 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase CoA_transf_3 PF02515.17 CRK16677.1 - 3e-105 352.3 0.0 4e-105 351.9 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III COesterase PF00135.28 CRK16677.1 - 3.7e-29 102.0 0.4 6.8e-26 91.2 0.6 3.0 2 1 1 3 3 3 2 Carboxylesterase family Abhydrolase_3 PF07859.13 CRK16677.1 - 0.008 16.0 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold CoA_trans PF01144.23 CRK16678.1 - 3.4e-101 337.2 3.9 1.4e-64 217.5 1.1 2.1 2 0 0 2 2 2 2 Coenzyme A transferase Mal_decarbox_Al PF16957.5 CRK16678.1 - 0.004 15.6 0.1 0.1 10.9 0.1 2.1 2 0 0 2 2 2 2 Malonate decarboxylase, alpha subunit, transporter Fe-ADH PF00465.19 CRK16679.1 - 2e-55 188.1 0.0 2.5e-32 112.1 0.0 2.0 1 1 1 2 2 2 2 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 CRK16679.1 - 1.5e-06 28.1 0.8 0.0045 16.7 0.1 3.0 3 0 0 3 3 3 2 Iron-containing alcohol dehydrogenase Thiolase_N PF00108.23 CRK16680.1 - 2.6e-71 240.0 0.8 6.3e-70 235.5 0.2 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CRK16680.1 - 1.2e-42 144.4 0.1 1.9e-42 143.8 0.1 1.3 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 CRK16680.1 - 5.3e-07 29.5 0.2 1.2e-06 28.3 0.2 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Prolactin_RP PF15172.6 CRK16680.1 - 0.018 14.7 0.9 0.038 13.6 0.1 2.0 2 0 0 2 2 2 0 Prolactin-releasing peptide ACP_syn_III PF08545.10 CRK16680.1 - 0.095 12.6 0.2 0.83 9.5 0.1 2.3 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Fungal_trans PF04082.18 CRK16681.1 - 1.2e-10 40.9 0.0 2.2e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain HgmA PF04209.13 CRK16683.1 - 4.8e-135 450.6 0.0 5.5e-135 450.4 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Arg_decarb_HB PF17810.1 CRK16683.1 - 0.099 12.9 0.0 0.54 10.5 0.0 2.0 2 0 0 2 2 2 0 Arginine decarboxylase helical bundle domain Lyase_1 PF00206.20 CRK16685.1 - 5e-51 174.0 0.1 1.8e-50 172.1 0.1 1.8 1 1 0 1 1 1 1 Lyase ADSL_C PF10397.9 CRK16685.1 - 8.1e-20 71.1 0.0 6.9e-19 68.2 0.0 2.4 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus FumaraseC_C PF10415.9 CRK16685.1 - 0.052 14.0 0.1 1.5 9.3 0.0 3.1 4 0 0 4 4 4 0 Fumarase C C-terminus TRI12 PF06609.13 CRK16687.1 - 7.3e-55 186.5 17.4 8.8e-55 186.2 17.4 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 CRK16687.1 - 8.6e-26 90.7 53.6 1.4e-24 86.7 51.2 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily DUF3522 PF12036.8 CRK16687.1 - 0.0081 16.5 0.2 0.0081 16.5 0.2 2.5 2 1 1 3 3 3 1 Protein of unknown function (DUF3522) GMC_oxred_N PF00732.19 CRK16689.1 - 1.9e-67 227.7 0.1 2.7e-67 227.2 0.1 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CRK16689.1 - 5.3e-40 137.2 0.0 9.3e-40 136.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 CRK16689.1 - 5.2e-05 23.0 1.1 0.0012 18.5 0.0 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CRK16689.1 - 0.00034 20.8 0.3 0.0011 19.1 0.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CRK16689.1 - 0.0064 15.6 0.1 0.02 14.0 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 CRK16689.1 - 0.0086 15.2 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 CRK16689.1 - 0.01 15.1 0.1 0.044 13.0 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CRK16689.1 - 0.093 12.0 0.0 0.61 9.3 0.0 2.0 2 0 0 2 2 2 0 Thi4 family OTT_1508_deam PF14441.6 CRK16691.1 - 1.4e-16 60.3 2.1 5.8e-16 58.2 0.1 2.4 2 0 0 2 2 2 1 OTT_1508-like deaminase Fungal_trans_2 PF11951.8 CRK16691.1 - 0.011 14.6 0.1 0.021 13.6 0.1 1.5 1 0 0 1 1 1 0 Fungal specific transcription factor domain Glyco_hydro_43 PF04616.14 CRK16696.1 - 8.6e-54 182.8 1.8 1.1e-53 182.4 1.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 CRK16696.1 - 3.2e-31 108.6 0.0 5.9e-31 107.8 0.0 1.4 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain DUF5005 PF16396.5 CRK16696.1 - 0.0095 14.7 0.1 0.15 10.8 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF5005) HET PF06985.11 CRK16697.1 - 3.9e-33 114.9 0.1 6.4e-33 114.2 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) LysM PF01476.20 CRK16699.1 - 1.5e-10 41.0 0.0 2.2e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 LysM domain DUF903 PF06004.12 CRK16699.1 - 0.026 14.4 1.0 0.052 13.4 1.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF903) Actino_peptide PF14408.6 CRK16699.1 - 0.031 14.4 0.1 0.049 13.8 0.1 1.3 1 0 0 1 1 1 0 Ribosomally synthesised peptide in actinomycetes ExoD PF06055.12 CRK16701.1 - 0.16 11.4 0.1 0.18 11.2 0.1 1.2 1 0 0 1 1 1 0 Exopolysaccharide synthesis, ExoD p450 PF00067.22 CRK16702.1 - 2.5e-15 56.2 0.1 3.1e-15 55.9 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 FMO-like PF00743.19 CRK16704.1 - 6.1e-11 41.4 0.0 2.6e-08 32.7 0.1 2.8 2 2 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 CRK16704.1 - 2e-09 37.5 0.0 4.8e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 CRK16704.1 - 5.5e-05 22.6 0.0 0.00026 20.4 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lectin_N PF03954.14 CRK16704.1 - 0.0023 17.7 0.5 0.0065 16.2 0.5 1.7 1 0 0 1 1 1 1 Hepatic lectin, N-terminal domain Thi4 PF01946.17 CRK16704.1 - 0.003 16.8 0.0 0.0062 15.8 0.0 1.4 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 CRK16704.1 - 0.004 16.8 0.0 0.58 9.7 0.0 3.2 2 1 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 CRK16704.1 - 0.015 15.3 0.0 0.059 13.4 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding K_oxygenase PF13434.6 CRK16704.1 - 0.079 12.1 0.0 20 4.2 0.0 2.9 3 1 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) AMP-binding PF00501.28 CRK16706.1 - 5.4e-95 318.5 0.0 7.6e-95 318.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CRK16706.1 - 4.5e-10 40.4 2.1 1.9e-09 38.4 1.8 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain adh_short_C2 PF13561.6 CRK16710.1 - 1.3e-34 119.8 0.0 2.8e-30 105.6 0.0 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRK16710.1 - 1.9e-24 86.2 1.1 1.3e-22 80.3 0.4 2.3 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 CRK16710.1 - 5.6e-06 26.4 0.6 1.4e-05 25.1 0.3 1.7 2 0 0 2 2 2 1 KR domain ADH_zinc_N PF00107.26 CRK16712.1 - 3.2e-23 82.1 1.4 7.8e-23 80.9 0.2 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CRK16712.1 - 2.4e-16 59.6 0.3 4e-16 58.8 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain 2-Hacid_dh_C PF02826.19 CRK16712.1 - 0.00063 19.1 0.0 0.0014 18.1 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 CRK16712.1 - 0.001 20.1 0.0 0.0018 19.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 CRK16712.1 - 0.0019 18.8 0.1 0.0046 17.6 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain TrkA_N PF02254.18 CRK16712.1 - 0.0059 16.9 0.2 0.019 15.2 0.1 1.9 2 0 0 2 2 2 1 TrkA-N domain Methyltransf_11 PF08241.12 CRK16712.1 - 0.0088 16.7 0.1 0.02 15.6 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain AlaDh_PNT_C PF01262.21 CRK16712.1 - 0.0098 15.2 0.2 0.017 14.4 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain CMAS PF02353.20 CRK16712.1 - 0.02 14.2 0.1 0.032 13.5 0.1 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase 3HCDH_N PF02737.18 CRK16712.1 - 0.044 13.7 1.7 0.11 12.3 0.5 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_12 PF08242.12 CRK16712.1 - 0.11 13.2 0.0 0.21 12.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Aldedh PF00171.22 CRK16714.1 - 2e-156 521.1 0.0 2.3e-156 520.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 CRK16714.1 - 0.0013 17.8 0.0 0.0023 17.0 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) NACHT_N PF17100.5 CRK16715.1 - 1e-28 100.7 2.3 8.7e-27 94.4 2.1 3.1 2 1 0 2 2 2 1 N-terminal domain of NWD NACHT-NTPase NmrA PF05368.13 CRK16715.1 - 9.9e-14 51.5 0.0 2.3e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family Ank_2 PF12796.7 CRK16715.1 - 2.1e-11 44.3 0.1 0.00025 21.6 0.0 4.4 4 1 0 4 4 3 2 Ankyrin repeats (3 copies) NACHT PF05729.12 CRK16715.1 - 3.3e-10 40.1 0.1 8.8e-10 38.8 0.1 1.7 1 0 0 1 1 1 1 NACHT domain Ank_5 PF13857.6 CRK16715.1 - 5.9e-10 39.2 0.2 2.2e-07 31.0 0.1 3.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 CRK16715.1 - 3.2e-08 34.0 0.2 0.0024 18.4 0.0 4.8 2 2 2 4 4 4 2 Ankyrin repeats (many copies) AAA_16 PF13191.6 CRK16715.1 - 5e-06 27.0 0.8 3.2e-05 24.4 0.4 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 CRK16715.1 - 2.1e-05 24.8 0.0 2.1e-05 24.8 0.0 2.8 3 0 0 3 3 3 1 AAA domain Ank PF00023.30 CRK16715.1 - 4.3e-05 23.8 1.0 0.033 14.6 0.0 4.6 5 0 0 5 5 3 1 Ankyrin repeat NAD_binding_10 PF13460.6 CRK16715.1 - 0.0015 18.5 0.0 0.0041 17.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)H-binding AAA_25 PF13481.6 CRK16715.1 - 0.013 15.1 0.0 0.066 12.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain Ank_3 PF13606.6 CRK16715.1 - 0.029 14.9 0.0 2.4 9.0 0.0 4.1 4 0 0 4 4 2 0 Ankyrin repeat KAP_NTPase PF07693.14 CRK16715.1 - 0.032 13.5 0.0 1.3 8.2 0.1 2.4 1 1 1 2 2 2 0 KAP family P-loop domain KR PF08659.10 CRK16715.1 - 0.054 13.4 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 KR domain 3Beta_HSD PF01073.19 CRK16715.1 - 0.088 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family AAA PF00004.29 CRK16715.1 - 0.12 12.8 0.0 0.46 10.9 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Semialdhyde_dh PF01118.24 CRK16715.1 - 0.16 12.4 0.1 0.56 10.7 0.0 2.0 2 0 0 2 2 1 0 Semialdehyde dehydrogenase, NAD binding domain Aa_trans PF01490.18 CRK16717.1 - 5.9e-16 58.2 25.8 4.5e-10 38.8 15.2 2.1 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein NmrA PF05368.13 CRK16719.1 - 1.5e-38 132.7 0.0 1.9e-38 132.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 CRK16719.1 - 5.5e-11 42.7 0.1 7.7e-11 42.2 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding TrkA_N PF02254.18 CRK16719.1 - 0.0024 18.1 0.0 0.0041 17.4 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain Epimerase PF01370.21 CRK16719.1 - 0.0026 17.2 0.0 0.0035 16.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 CRK16719.1 - 0.06 13.8 0.0 0.11 13.0 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 CRK16719.1 - 0.19 11.9 0.5 0.43 10.7 0.1 1.7 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.25 CRK16721.1 - 1.4e-41 142.1 0.0 1.8e-41 141.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK16721.1 - 1.4e-31 109.9 0.0 1.9e-31 109.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK16721.1 - 9.6e-05 22.4 0.0 0.00016 21.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CRK16721.1 - 0.00032 20.2 0.1 0.0017 17.9 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family YjeF_N PF03853.15 CRK16721.1 - 0.065 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus Acyl-CoA_dh_1 PF00441.24 CRK16725.1 - 7.3e-25 87.9 0.2 1.3e-24 87.1 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CRK16725.1 - 1.6e-12 48.1 0.2 4.6e-12 46.6 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 CRK16725.1 - 3.3e-10 40.0 0.0 5.6e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 CRK16725.1 - 1.4e-08 35.1 0.0 2.3e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain FMO-like PF00743.19 CRK16729.1 - 3.3e-15 55.5 0.0 2.6e-12 46.0 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 CRK16729.1 - 4.5e-12 46.0 0.0 1.3e-11 44.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 CRK16729.1 - 6.6e-06 26.2 0.0 8.4e-05 22.6 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 CRK16729.1 - 7e-06 25.4 0.0 0.33 10.1 0.0 3.5 3 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 CRK16729.1 - 0.00058 19.5 0.0 0.016 14.8 0.0 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 CRK16729.1 - 0.1 11.8 0.0 0.37 10.0 0.0 1.8 2 0 0 2 2 2 0 Thi4 family Pyr_redox_3 PF13738.6 CRK16729.1 - 0.17 11.1 0.0 6.7 5.9 0.0 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans PF04082.18 CRK16731.1 - 3.4e-19 68.9 0.0 6.5e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK16731.1 - 2.5e-05 24.3 11.1 4.1e-05 23.6 11.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HD_5 PF13487.6 CRK16731.1 - 0.093 13.0 0.0 75 3.7 0.0 3.3 3 0 0 3 3 3 0 HD domain DUF1631 PF07793.11 CRK16731.1 - 0.13 10.7 1.5 0.31 9.4 1.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) MutS_V PF00488.21 CRK16735.1 - 1.6e-66 223.9 1.2 2.3e-66 223.5 0.3 1.7 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 CRK16735.1 - 1.5e-39 136.2 0.1 4.2e-39 134.7 0.0 1.8 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.20 CRK16735.1 - 2.8e-30 104.8 0.0 6.6e-30 103.7 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 CRK16735.1 - 5e-17 62.5 0.0 1.5e-16 60.9 0.0 1.8 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 CRK16735.1 - 6.2e-14 52.1 0.6 1.3e-13 51.1 0.6 1.6 1 0 0 1 1 1 1 MutS family domain IV AAA_23 PF13476.6 CRK16735.1 - 0.0022 18.5 1.9 0.02 15.4 0.2 2.5 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 CRK16735.1 - 0.047 13.5 0.2 0.12 12.1 0.2 1.8 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_27 PF13514.6 CRK16735.1 - 0.056 13.0 0.3 0.15 11.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 CRK16735.1 - 0.085 12.6 0.2 0.18 11.5 0.2 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CRK16735.1 - 0.088 12.6 0.1 0.24 11.2 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain SPT6_acidic PF14632.6 CRK16735.1 - 0.31 11.7 13.3 0.77 10.4 11.4 2.6 1 1 1 2 2 2 0 Acidic N-terminal SPT6 Pkinase PF00069.25 CRK16737.1 - 1.7e-40 139.1 0.0 5e-40 137.5 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK16737.1 - 1.5e-28 99.8 0.0 2.2e-28 99.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CRK16737.1 - 0.014 14.7 0.0 0.14 11.5 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CRK16737.1 - 0.015 14.7 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like adh_short PF00106.25 CRK16739.1 - 3.9e-19 68.9 0.1 5.6e-19 68.4 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK16739.1 - 2.7e-18 66.4 0.3 3.6e-18 66.0 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK16739.1 - 1.7e-06 28.1 0.1 2.4e-06 27.6 0.1 1.2 1 0 0 1 1 1 1 KR domain Ldh_1_N PF00056.23 CRK16739.1 - 0.091 12.9 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain adh_short PF00106.25 CRK16741.1 - 3.9e-12 46.0 0.1 4.8e-12 45.8 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK16741.1 - 2.7e-11 43.5 0.2 3.4e-11 43.2 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK16741.1 - 6.5e-06 26.2 0.1 7.7e-06 25.9 0.1 1.0 1 0 0 1 1 1 1 KR domain Ldh_1_N PF00056.23 CRK16741.1 - 0.029 14.5 0.1 0.034 14.2 0.1 1.2 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 CRK16741.1 - 0.13 13.0 0.0 0.15 12.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.25 CRK16743.1 - 3.2e-43 148.0 0.0 9.3e-43 146.5 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK16743.1 - 1.3e-30 106.6 0.0 1.8e-30 106.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CRK16743.1 - 0.015 14.7 0.0 0.14 11.5 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family MutS_V PF00488.21 CRK16745.1 - 7.3e-08 32.7 0.0 1.3e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 MutS domain V Zn_clus PF00172.18 CRK16745.1 - 7.1e-06 26.0 11.1 1.1e-05 25.4 11.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 CRK16745.1 - 9.5e-05 21.6 0.0 0.00015 20.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1631 PF07793.11 CRK16745.1 - 0.0051 15.3 1.0 0.0072 14.8 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1631) FMO-like PF00743.19 CRK16747.1 - 1.5e-15 56.7 0.0 1.7e-12 46.6 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 CRK16747.1 - 4.3e-12 46.1 0.0 1.3e-11 44.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 CRK16747.1 - 4.4e-06 26.8 0.0 3.7e-05 23.7 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 CRK16747.1 - 6e-06 25.6 0.0 0.33 10.1 0.0 3.4 3 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 CRK16747.1 - 0.0027 17.4 0.0 0.021 14.4 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 CRK16747.1 - 0.099 11.9 0.0 2.7 7.1 0.0 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CRK16747.1 - 0.11 11.7 0.0 0.37 10.0 0.0 1.8 2 0 0 2 2 2 0 Thi4 family DUF4188 PF13826.6 CRK16747.1 - 0.11 12.8 0.1 0.37 11.2 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4188) 120_Rick_ant PF12574.8 CRK16750.1 - 0.0084 15.3 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 1 120 KDa Rickettsia surface antigen adh_short PF00106.25 CRK16753.1 - 2e-41 141.6 0.1 5e-40 137.1 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.13 CRK16753.1 - 6.3e-39 133.9 0.1 1.7e-36 125.9 0.0 2.2 2 0 0 2 2 2 2 NmrA-like family adh_short_C2 PF13561.6 CRK16753.1 - 3.2e-31 108.7 0.1 1.5e-29 103.2 0.0 2.5 3 0 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 CRK16753.1 - 2e-12 47.4 0.1 2.6e-10 40.5 0.0 2.2 2 0 0 2 2 2 2 NAD(P)H-binding Epimerase PF01370.21 CRK16753.1 - 7.2e-08 32.2 0.1 0.013 14.9 0.0 2.7 3 0 0 3 3 3 2 NAD dependent epimerase/dehydratase family KR PF08659.10 CRK16753.1 - 1.4e-06 28.3 0.3 0.00073 19.5 0.0 2.3 2 0 0 2 2 2 2 KR domain TrkA_N PF02254.18 CRK16753.1 - 0.0014 18.8 0.1 0.0067 16.7 0.0 2.0 2 0 0 2 2 2 1 TrkA-N domain Aa_trans PF01490.18 CRK16754.1 - 6.9e-23 81.0 32.9 8.6e-23 80.7 32.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Fungal_trans_2 PF11951.8 CRK16757.1 - 3.8e-19 68.8 0.2 4.8e-19 68.4 0.2 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain TFIIB PF00382.19 CRK16757.1 - 0.034 14.2 0.0 0.1 12.7 0.0 1.8 1 1 0 1 1 1 0 Transcription factor TFIIB repeat Methyltransf_33 PF10017.9 CRK16758.1 - 2.5e-77 260.1 0.0 3e-77 259.8 0.0 1.0 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent zf-C2H2 PF00096.26 CRK16760.1 - 1e-22 79.2 25.9 7e-06 26.2 0.2 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CRK16760.1 - 2.1e-17 62.6 25.6 1.7e-06 28.2 1.2 5.5 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 CRK16760.1 - 2.2e-07 31.1 39.0 0.0041 17.8 1.3 5.3 5 0 0 5 5 4 4 C2H2-type zinc finger zf-met PF12874.7 CRK16760.1 - 0.00021 21.6 7.1 1.1 9.8 0.0 4.2 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 CRK16760.1 - 0.00098 18.8 8.1 0.02 14.7 0.8 3.2 3 0 0 3 3 3 2 zinc-finger C2H2-type zf_UBZ PF18439.1 CRK16760.1 - 0.0022 17.6 1.7 1.2 8.8 0.2 3.3 3 0 0 3 3 3 2 Ubiquitin-Binding Zinc Finger zf-C2H2_jaz PF12171.8 CRK16760.1 - 0.0039 17.4 8.3 12 6.3 0.0 4.6 5 0 0 5 5 4 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 CRK16760.1 - 0.42 10.6 7.6 9.8 6.2 0.3 3.5 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Zn-ribbon_8 PF09723.10 CRK16760.1 - 0.62 10.2 9.0 3.2 7.9 1.0 3.2 1 1 3 4 4 4 0 Zinc ribbon domain DZR PF12773.7 CRK16760.1 - 1.1 9.3 7.7 66 3.6 7.7 2.4 1 1 0 1 1 1 0 Double zinc ribbon zf-LYAR PF08790.11 CRK16760.1 - 1.1 9.2 4.0 6.2 6.8 0.1 3.5 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger Ogr_Delta PF04606.12 CRK16760.1 - 1.7 8.7 9.2 3.3 7.8 0.4 2.5 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger DUF2256 PF10013.9 CRK16760.1 - 2.9 8.1 8.5 22 5.3 0.0 3.7 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) Zn_ribbon_recom PF13408.6 CRK16760.1 - 3 8.4 9.8 4.5 7.9 2.4 2.6 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain XPA_N PF01286.18 CRK16760.1 - 7.9 6.6 8.5 0.84 9.7 0.5 3.0 4 0 0 4 4 4 0 XPA protein N-terminal DSBA PF01323.20 CRK16761.1 - 5.3e-26 91.6 0.0 3.2e-13 49.9 0.0 2.1 2 0 0 2 2 2 2 DSBA-like thioredoxin domain Thioredoxin_5 PF13743.6 CRK16761.1 - 0.011 15.4 0.0 0.026 14.2 0.0 1.6 2 0 0 2 2 2 0 Thioredoxin Thioredoxin_4 PF13462.6 CRK16761.1 - 0.082 13.1 0.0 0.22 11.7 0.0 1.6 2 0 0 2 2 2 0 Thioredoxin Thioredoxin_3 PF13192.6 CRK16761.1 - 0.11 12.6 0.0 8.3 6.5 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin domain F-actin_cap_A PF01267.17 CRK16763.1 - 1.4e-79 267.3 0.1 1.8e-72 244.0 0.0 2.1 1 1 1 2 2 2 2 F-actin capping protein alpha subunit Cyt-b5 PF00173.28 CRK16763.1 - 1.3e-22 79.8 0.2 2.4e-22 78.9 0.2 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ACAS_N PF16177.5 CRK16763.1 - 0.094 12.6 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Acetyl-coenzyme A synthetase N-terminus Transket_pyr PF02779.24 CRK16764.1 - 7e-41 139.8 0.7 1.2e-40 139.1 0.2 1.6 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 CRK16764.1 - 4.4e-33 113.8 0.1 1.1e-32 112.5 0.0 1.7 2 0 0 2 2 2 1 Transketolase, C-terminal domain PFOR_II PF17147.4 CRK16764.1 - 0.00073 19.8 0.0 0.0022 18.3 0.0 1.8 2 0 0 2 2 2 1 Pyruvate:ferredoxin oxidoreductase core domain II DUF2278 PF10042.9 CRK16764.1 - 0.13 12.2 0.0 0.21 11.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2278) adh_short PF00106.25 CRK16765.1 - 2.6e-30 105.4 0.0 6.1e-27 94.4 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CRK16765.1 - 9.6e-22 77.7 0.0 6.7e-21 74.9 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK16765.1 - 3e-09 37.1 0.1 5.1e-09 36.3 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CRK16765.1 - 1.2e-05 24.9 0.0 4.3e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CRK16765.1 - 0.001 18.5 0.0 0.069 12.5 0.0 2.1 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 CRK16765.1 - 0.0047 16.1 0.0 0.0093 15.1 0.0 1.5 1 0 0 1 1 1 1 RmlD substrate binding domain F420_oxidored PF03807.17 CRK16765.1 - 0.0061 17.1 0.1 0.015 15.9 0.0 1.8 2 0 0 2 2 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.6 CRK16765.1 - 0.021 14.7 0.0 0.04 13.8 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H-binding NmrA PF05368.13 CRK16765.1 - 0.033 13.8 0.3 0.061 12.9 0.3 1.4 1 0 0 1 1 1 0 NmrA-like family DUF1776 PF08643.10 CRK16765.1 - 0.041 13.2 0.0 0.15 11.4 0.0 1.8 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.15 CRK16765.1 - 0.052 12.7 0.0 0.074 12.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 CRK16765.1 - 0.2 10.8 0.5 0.57 9.3 0.2 2.0 2 1 0 2 2 2 0 Male sterility protein Glyco_trans_4_4 PF13579.6 CRK16765.1 - 1.6 9.1 6.8 17 5.8 6.8 2.4 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain Cellulase PF00150.18 CRK16767.1 - 9.9e-12 44.9 0.7 2e-11 43.9 0.7 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PLAT PF01477.23 CRK16767.1 - 0.016 15.8 0.3 0.041 14.4 0.0 1.8 2 0 0 2 2 2 0 PLAT/LH2 domain EphA2_TM PF14575.6 CRK16767.1 - 0.053 14.4 0.0 0.053 14.4 0.0 3.0 3 1 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain ODV-E18 PF10717.9 CRK16767.1 - 0.067 13.1 0.3 0.13 12.2 0.3 1.4 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 MFS_1 PF07690.16 CRK16768.1 - 8.4e-38 130.2 35.2 8.4e-38 130.2 35.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK16768.1 - 1.5e-09 37.2 25.7 9.8e-09 34.6 25.7 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 CRK16768.1 - 3.4e-05 22.5 6.0 3.4e-05 22.5 6.0 2.2 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) PAS PF00989.25 CRK16768.1 - 0.026 14.5 0.0 0.052 13.5 0.0 1.4 1 0 0 1 1 1 0 PAS fold Zn_clus PF00172.18 CRK16768.1 - 0.18 12.0 1.6 0.52 10.5 1.6 1.8 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Flavokinase PF01687.17 CRK16770.1 - 1.6e-06 28.3 0.4 0.0019 18.5 0.1 2.1 1 1 1 2 2 2 2 Riboflavin kinase ETF_alpha PF00766.19 CRK16770.1 - 0.045 13.8 0.0 0.059 13.4 0.0 1.2 1 0 0 1 1 1 0 Electron transfer flavoprotein FAD-binding domain zf-RING_2 PF13639.6 CRK16771.1 - 1.2e-08 35.1 8.0 2.5e-08 34.1 8.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 CRK16771.1 - 2.7e-05 24.4 7.1 9.3e-05 22.6 7.1 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 CRK16771.1 - 0.00045 20.0 7.4 0.0012 18.6 7.4 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CRK16771.1 - 0.0015 18.5 4.6 0.0015 18.5 2.8 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 CRK16771.1 - 0.0015 18.3 4.5 0.0036 17.1 4.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CRK16771.1 - 0.0055 16.7 6.5 0.0072 16.3 4.9 2.1 1 1 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 CRK16771.1 - 0.011 15.6 3.8 0.68 9.8 0.9 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 CRK16771.1 - 0.019 14.8 5.5 0.046 13.6 5.5 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 CRK16771.1 - 0.034 14.3 5.2 0.11 12.7 5.2 1.9 1 1 0 1 1 1 0 Zinc-binding RING-finger UBZ_FAAP20 PF15750.5 CRK16771.1 - 0.13 12.3 1.8 3.3 7.7 0.2 2.6 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger Rad50_zn_hook PF04423.14 CRK16771.1 - 0.15 11.9 2.6 3.2 7.7 0.3 2.6 3 0 0 3 3 2 0 Rad50 zinc hook motif Zn-C2H2_12 PF18112.1 CRK16771.1 - 0.2 12.2 3.2 2.3 8.8 0.1 2.6 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-RING_11 PF17123.5 CRK16771.1 - 0.58 10.0 6.3 1.3 8.8 6.3 1.7 1 0 0 1 1 1 0 RING-like zinc finger Prok-RING_1 PF14446.6 CRK16771.1 - 1.1 9.2 4.1 18 5.3 0.1 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_5 PF14634.6 CRK16771.1 - 2.5 8.1 6.2 9.4 6.3 6.2 2.0 1 1 0 1 1 1 0 zinc-RING finger domain Hydrophobin_2 PF06766.11 CRK16773.1 - 8.4e-26 89.7 11.6 1.1e-25 89.3 11.6 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Pkinase PF00069.25 CRK16774.1 - 7.2e-59 199.3 0.0 9.5e-59 198.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK16774.1 - 9.6e-31 107.0 0.0 1.3e-30 106.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CRK16774.1 - 0.00097 18.5 0.0 0.0017 17.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CRK16774.1 - 0.032 13.0 0.0 0.047 12.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 CRK16774.1 - 0.034 13.5 0.0 0.053 12.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CRK16774.1 - 0.047 13.6 0.3 0.047 13.6 0.3 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family PAP1 PF08601.10 CRK16775.1 - 1.9e-37 129.9 1.6 2.3e-37 129.6 1.6 1.0 1 0 0 1 1 1 1 Transcription factor PAP1 SUI1 PF01253.22 CRK16775.1 - 0.046 14.2 0.3 0.076 13.5 0.2 1.5 1 1 0 1 1 1 0 Translation initiation factor SUI1 YPEB PF14620.6 CRK16775.1 - 0.12 11.7 0.1 0.14 11.5 0.1 1.0 1 0 0 1 1 1 0 YpeB sporulation Pkinase PF00069.25 CRK16776.1 - 2e-54 184.7 0.0 2.6e-54 184.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK16776.1 - 5.5e-29 101.2 0.0 7.1e-29 100.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CRK16776.1 - 0.00058 19.3 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CRK16776.1 - 0.018 15.0 0.2 0.033 14.1 0.2 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CRK16776.1 - 0.023 13.5 0.0 0.033 13.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 CRK16776.1 - 0.026 13.9 0.0 0.044 13.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family eRF1_1 PF03463.15 CRK16776.1 - 0.2 11.7 0.0 0.33 11.0 0.0 1.3 1 0 0 1 1 1 0 eRF1 domain 1 PAP1 PF08601.10 CRK16777.1 - 3.8e-98 329.6 41.0 9.4e-66 223.0 6.9 3.7 3 1 1 4 4 4 2 Transcription factor PAP1 bZIP_1 PF00170.21 CRK16777.1 - 5.4e-10 39.2 10.8 3.7e-09 36.6 9.9 2.3 2 0 0 2 2 2 1 bZIP transcription factor SHE3 PF17078.5 CRK16777.1 - 0.00045 20.0 4.6 0.0011 18.7 4.6 1.6 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 bZIP_Maf PF03131.17 CRK16777.1 - 0.021 15.4 7.6 0.021 15.4 7.6 2.1 1 1 1 2 2 2 0 bZIP Maf transcription factor DUF812 PF05667.11 CRK16777.1 - 0.031 13.2 4.3 0.048 12.6 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) dsrm PF00035.26 CRK16777.1 - 0.074 13.8 0.1 0.19 12.5 0.1 1.6 1 0 0 1 1 1 0 Double-stranded RNA binding motif CCDC158 PF15921.5 CRK16777.1 - 0.097 10.5 3.6 0.15 9.8 3.6 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 158 bZIP_2 PF07716.15 CRK16777.1 - 0.14 12.3 15.4 0.039 14.0 10.6 2.4 2 1 0 2 2 2 0 Basic region leucine zipper DUF4140 PF13600.6 CRK16777.1 - 0.26 11.7 1.9 0.88 10.0 1.9 2.0 2 0 0 2 2 1 0 N-terminal domain of unknown function (DUF4140) Csm1_N PF18504.1 CRK16777.1 - 0.58 10.5 4.9 0.42 11.0 0.4 2.3 1 1 1 2 2 2 0 Csm1 N-terminal domain UPF0242 PF06785.11 CRK16777.1 - 1.6 8.8 6.4 2.6 8.1 6.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Atg14 PF10186.9 CRK16777.1 - 5.5 6.0 9.4 9.9 5.1 9.4 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4407 PF14362.6 CRK16777.1 - 9.2 5.5 5.8 16 4.7 5.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) BSD PF03909.17 CRK16778.1 - 3.9e-19 68.4 0.1 8.5e-19 67.3 0.1 1.6 1 0 0 1 1 1 1 BSD domain Sigma70_r2 PF04542.14 CRK16778.1 - 0.01 15.6 0.3 0.065 13.0 0.0 2.3 2 0 0 2 2 2 0 Sigma-70 region 2 Suf PF05843.14 CRK16778.1 - 0.12 12.4 10.0 0.011 15.8 4.2 2.0 1 1 0 2 2 2 0 Suppressor of forked protein (Suf) WGG PF10273.9 CRK16779.1 - 9.9e-34 115.9 0.8 1.6e-33 115.2 0.8 1.3 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 RRP7 PF12923.7 CRK16779.1 - 0.014 15.5 0.7 0.21 11.7 0.0 2.4 2 0 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain Toxin_13 PF07822.11 CRK16779.1 - 0.13 12.4 0.4 0.28 11.3 0.4 1.5 1 0 0 1 1 1 0 Neurotoxin B-IV-like protein PBP1_TM PF14812.6 CRK16779.1 - 0.63 10.4 6.4 1.3 9.4 6.4 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Abhydrolase_3 PF07859.13 CRK16780.1 - 4.1e-40 137.9 0.0 7.7e-30 104.3 0.0 2.6 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 CRK16780.1 - 4.3e-14 52.2 0.0 2e-13 49.9 0.0 1.9 2 0 0 2 2 2 1 Steryl acetyl hydrolase COesterase PF00135.28 CRK16780.1 - 0.0044 16.0 0.2 0.033 13.1 0.2 2.0 1 1 0 1 1 1 1 Carboxylesterase family Hydrolase_4 PF12146.8 CRK16780.1 - 0.067 12.4 0.0 0.17 11.1 0.0 1.7 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Cation_efflux PF01545.21 CRK16781.1 - 5.1e-26 91.6 15.9 6.4e-26 91.3 15.9 1.1 1 0 0 1 1 1 1 Cation efflux family MRP-L27 PF09809.9 CRK16781.1 - 4e-13 49.2 0.1 1e-12 47.9 0.1 1.6 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 ZT_dimer PF16916.5 CRK16781.1 - 7.2e-09 35.7 0.1 1.5e-08 34.7 0.1 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter DUF423 PF04241.15 CRK16781.1 - 4.5 7.5 6.8 2.7 8.3 0.9 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF423) TctB PF07331.11 CRK16781.1 - 7.4 6.9 14.2 1.4 9.2 5.8 2.3 1 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family Zip PF02535.22 CRK16782.1 - 9.5e-53 179.5 0.0 1.2e-52 179.2 0.0 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter 2-Hacid_dh_C PF02826.19 CRK16784.1 - 1.6e-53 180.7 0.1 2.4e-53 180.2 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CRK16784.1 - 3.4e-37 127.1 1.0 1.3e-36 125.2 0.4 2.1 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.25 CRK16784.1 - 0.00072 19.3 0.2 0.0031 17.3 0.0 2.2 2 0 0 2 2 2 1 ACT domain XdhC_C PF13478.6 CRK16784.1 - 0.028 14.9 0.0 0.061 13.8 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain F420_oxidored PF03807.17 CRK16784.1 - 0.055 14.0 0.3 0.29 11.7 0.0 2.3 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_C PF03720.15 CRK16784.1 - 0.067 13.6 0.0 0.17 12.3 0.0 1.7 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain DUF21 PF01595.20 CRK16785.1 - 2.8e-33 115.1 0.0 4.6e-33 114.4 0.0 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 CRK16785.1 - 0.00014 22.3 0.2 0.018 15.5 0.0 3.3 3 0 0 3 3 3 1 CBS domain Dioxygenase_C PF00775.21 CRK16787.1 - 2.6e-26 92.2 0.0 3.9e-26 91.6 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 CRK16787.1 - 3.2e-25 87.8 0.1 6.6e-25 86.8 0.1 1.5 1 0 0 1 1 1 1 Catechol dioxygenase N terminus ArsB PF02040.15 CRK16787.1 - 2.2e-07 30.6 16.6 2.2e-06 27.3 7.1 2.1 2 0 0 2 2 2 2 Arsenical pump membrane protein HPP PF04982.13 CRK16787.1 - 0.66 10.2 6.5 0.19 11.9 2.3 2.2 2 0 0 2 2 2 0 HPP family MFS_1 PF07690.16 CRK16790.1 - 2.3e-18 66.2 19.6 3.1e-18 65.9 19.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK16790.1 - 1.3e-07 30.9 10.5 1.6e-07 30.6 10.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter TF_Otx PF03529.13 CRK16790.1 - 0.017 15.5 0.5 0.099 13.0 0.1 2.3 1 1 2 3 3 3 0 Otx1 transcription factor Zn_clus PF00172.18 CRK16791.1 - 1.4e-08 34.7 10.8 2.4e-08 34.0 10.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2OG-FeII_Oxy_3 PF13640.6 CRK16792.1 - 1.5e-09 38.6 0.0 3.5e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fungal_trans_2 PF11951.8 CRK16792.1 - 6e-08 31.9 0.1 1.8e-05 23.7 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK16792.1 - 5.3e-07 29.7 11.2 1e-06 28.7 11.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RAP1 PF07218.11 CRK16792.1 - 6.7 4.9 6.1 9.6 4.3 6.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Thioredoxin_6 PF13848.6 CRK16793.1 - 2.1e-10 40.8 0.0 1.1e-08 35.2 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.20 CRK16793.1 - 4.4e-05 23.4 0.0 0.0014 18.6 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin AAA PF00004.29 CRK16794.1 - 3e-16 60.1 0.0 4.7e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 CRK16794.1 - 2.5e-14 53.4 0.0 6.3e-14 52.1 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 CRK16794.1 - 2.7e-11 43.5 0.1 8.7e-10 38.6 0.0 2.5 2 1 0 2 2 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 CRK16794.1 - 3.4e-08 33.6 0.0 6.9e-08 32.6 0.0 1.6 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 CRK16794.1 - 4.8e-07 30.0 0.1 1.5e-06 28.4 0.0 1.9 2 0 0 2 2 1 1 AAA C-terminal domain AAA_30 PF13604.6 CRK16794.1 - 1.2e-06 28.4 0.1 5.8e-06 26.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 CRK16794.1 - 2.8e-06 27.2 0.0 4.5e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CRK16794.1 - 4.3e-06 26.8 0.1 3.4e-05 23.9 0.0 2.4 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CRK16794.1 - 9.5e-06 25.9 0.0 2.4e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CRK16794.1 - 1.2e-05 25.8 0.0 0.00017 22.0 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_11 PF13086.6 CRK16794.1 - 1.2e-05 25.2 0.1 0.0002 21.2 0.0 2.3 1 1 2 3 3 3 1 AAA domain DUF815 PF05673.13 CRK16794.1 - 0.00027 20.2 0.0 0.00042 19.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 CRK16794.1 - 0.00038 20.2 0.0 0.00061 19.5 0.0 1.2 1 0 0 1 1 1 1 Sigma-54 interaction domain DNA_pol3_delta PF06144.13 CRK16794.1 - 0.00054 19.8 0.0 0.00092 19.0 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit RuvB_N PF05496.12 CRK16794.1 - 0.0006 19.6 0.0 0.0014 18.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 CRK16794.1 - 0.00067 19.7 0.0 0.0015 18.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CRK16794.1 - 0.001 19.4 0.0 0.0034 17.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.11 CRK16794.1 - 0.0021 17.9 0.0 0.017 15.0 0.0 2.4 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 CRK16794.1 - 0.003 17.8 0.0 0.0057 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 CRK16794.1 - 0.0043 16.5 0.0 0.033 13.6 0.0 2.1 2 0 0 2 2 2 1 Bacterial TniB protein Mg_chelatase PF01078.21 CRK16794.1 - 0.0086 15.5 0.1 0.031 13.7 0.1 2.0 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 CRK16794.1 - 0.01 16.4 0.0 0.018 15.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 CRK16794.1 - 0.012 15.1 0.0 1.3 8.5 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein ResIII PF04851.15 CRK16794.1 - 0.012 15.6 0.0 0.074 13.0 0.0 2.0 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_7 PF12775.7 CRK16794.1 - 0.019 14.5 0.0 0.038 13.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF2075 PF09848.9 CRK16794.1 - 0.034 13.4 0.0 0.053 12.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.6 CRK16794.1 - 0.056 13.0 0.0 0.2 11.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 CRK16794.1 - 0.12 12.1 0.1 2.1 8.1 0.0 2.4 1 1 2 3 3 3 0 DEAD/DEAH box helicase RNA_helicase PF00910.22 CRK16794.1 - 0.16 12.3 0.0 0.31 11.4 0.0 1.6 1 1 0 1 1 1 0 RNA helicase Fringe PF02434.16 CRK16795.1 - 5.8e-07 29.2 1.0 6.9e-06 25.7 1.0 2.2 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 CRK16795.1 - 0.0047 16.8 0.1 0.014 15.2 0.0 1.6 1 1 0 1 1 1 1 Galactosyltransferase PAN_4 PF14295.6 CRK16795.1 - 2.6 8.0 5.7 0.21 11.5 0.3 2.0 2 0 0 2 2 2 0 PAN domain RRM_1 PF00076.22 CRK16796.1 - 0.00016 21.4 0.0 0.00023 20.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MT PF12777.7 CRK16796.1 - 0.084 11.9 0.0 0.086 11.9 0.0 1.1 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor Pkinase PF00069.25 CRK16799.1 - 7.2e-37 127.2 0.1 7.8e-37 127.1 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK16799.1 - 4.4e-08 32.7 0.0 5.6e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CRK16799.1 - 4.8e-07 29.9 0.1 7.2e-07 29.4 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CRK16799.1 - 0.003 16.4 0.0 0.0037 16.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 CRK16799.1 - 0.0045 16.6 0.3 0.016 14.8 0.1 1.9 2 0 0 2 2 2 1 Choline/ethanolamine kinase Kinase-like PF14531.6 CRK16799.1 - 0.011 15.1 0.0 0.014 14.8 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 CRK16799.1 - 0.013 14.9 0.2 0.019 14.3 0.2 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 CRK16799.1 - 0.13 11.3 0.1 0.23 10.5 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 ABC_tran_CTD PF16326.5 CRK16800.1 - 1.7e-05 24.9 4.0 1.7e-05 24.9 4.0 2.8 2 2 0 2 2 2 1 ABC transporter C-terminal domain EzrA PF06160.12 CRK16800.1 - 0.0034 15.6 15.0 0.0044 15.3 15.0 1.2 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Fez1 PF06818.15 CRK16800.1 - 0.057 13.9 17.7 0.079 13.4 17.7 1.2 1 0 0 1 1 1 0 Fez1 YabA PF06156.13 CRK16800.1 - 0.36 11.5 6.0 1.8 9.2 2.3 2.5 1 1 1 2 2 2 0 Initiation control protein YabA PRKG1_interact PF15898.5 CRK16800.1 - 0.39 11.6 20.4 0.064 14.2 6.3 2.6 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain V_ATPase_I PF01496.19 CRK16800.1 - 0.44 8.4 10.6 0.52 8.2 10.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6_N PF17675.1 CRK16800.1 - 0.7 10.4 27.2 0.38 11.3 21.5 2.7 1 1 2 3 3 3 0 Apg6 coiled-coil region Golgin_A5 PF09787.9 CRK16800.1 - 0.77 9.2 17.3 1.1 8.6 17.3 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 Jnk-SapK_ap_N PF09744.9 CRK16800.1 - 1.3 9.2 20.7 4 7.7 13.8 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Fib_alpha PF08702.10 CRK16800.1 - 1.6 8.9 8.6 4 7.6 7.8 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Occludin_ELL PF07303.13 CRK16800.1 - 1.7 9.4 16.3 4.7 8.0 0.7 2.9 1 1 2 3 3 3 0 Occludin homology domain DUF724 PF05266.14 CRK16800.1 - 3.8 7.3 19.4 8.1 6.2 6.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF724) SlyX PF04102.12 CRK16800.1 - 5.4 7.7 9.1 12 6.6 0.1 3.2 1 1 1 3 3 3 0 SlyX zf-C4H2 PF10146.9 CRK16800.1 - 5.5 7.2 13.6 3.6 7.9 10.7 2.0 1 1 0 1 1 1 0 Zinc finger-containing protein CSN5_C PF18323.1 CRK16800.1 - 6.1 7.8 13.3 9.1e+02 0.9 13.3 2.6 1 1 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain FUSC PF04632.12 CRK16800.1 - 7.8 4.9 9.9 9 4.7 9.9 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family PALP PF00291.25 CRK16802.1 - 1.9e-65 221.2 4.1 2.5e-65 220.8 4.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme tRNA-synt_2c PF01411.19 CRK16802.1 - 0.00062 18.4 0.1 0.00089 17.9 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) DUF4527 PF15030.6 CRK16818.1 - 0.0017 17.9 0.5 0.0022 17.5 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4527) FTA4 PF13093.6 CRK16818.1 - 0.0035 17.3 0.5 0.0048 16.8 0.5 1.2 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 HMMR_N PF15905.5 CRK16818.1 - 0.017 14.6 0.4 0.024 14.1 0.4 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal SlyX PF04102.12 CRK16818.1 - 0.028 15.0 1.2 3.6 8.3 0.5 2.4 1 1 1 2 2 2 0 SlyX DASH_Spc34 PF08657.10 CRK16818.1 - 0.031 14.1 0.2 0.042 13.6 0.2 1.2 1 0 0 1 1 1 0 DASH complex subunit Spc34 FapA PF03961.13 CRK16818.1 - 0.046 12.3 0.2 0.052 12.1 0.2 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A RF-1 PF00472.20 CRK16818.1 - 0.05 13.5 2.6 0.085 12.8 0.4 2.3 1 1 1 2 2 2 0 RF-1 domain DUF896 PF05979.12 CRK16818.1 - 0.14 12.0 0.4 0.38 10.7 0.4 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF896) DUF1043 PF06295.12 CRK16818.1 - 0.17 11.9 1.7 0.21 11.6 1.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) TPR_1 PF00515.28 CRK16850.1 - 3.1e-23 80.6 1.8 2.1e-08 33.6 0.0 4.9 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 CRK16850.1 - 1.2e-21 75.0 3.2 4.2e-07 29.6 0.1 5.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 CRK16850.1 - 5.3e-17 61.2 4.0 3.3e-08 33.1 0.1 4.7 3 2 2 5 5 5 2 TPR repeat TPR_16 PF13432.6 CRK16850.1 - 4.6e-16 59.2 1.4 5e-07 30.3 0.0 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 CRK16850.1 - 8e-16 56.9 0.8 6.3e-06 26.0 0.0 5.0 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 CRK16850.1 - 2.6e-14 52.7 3.7 1.1e-06 29.0 0.0 5.1 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 CRK16850.1 - 3.9e-14 52.9 0.8 9.5e-05 22.8 0.0 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 CRK16850.1 - 1.4e-13 49.8 1.5 0.014 15.4 0.0 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.6 CRK16850.1 - 5.3e-13 48.4 1.7 0.00074 19.7 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 CRK16850.1 - 6e-11 42.5 3.9 0.0071 16.6 0.2 4.0 2 1 1 4 4 4 3 Tetratricopeptide repeat TPR_20 PF14561.6 CRK16850.1 - 6.6e-09 36.0 0.1 0.019 15.3 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 CRK16850.1 - 1.7e-08 34.5 1.4 0.0039 17.3 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 CRK16850.1 - 4.8e-08 33.1 1.3 0.17 12.6 0.0 5.3 5 1 0 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CRK16850.1 - 8.5e-06 25.9 2.7 0.0032 17.7 0.4 2.8 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 CRK16850.1 - 7.8e-05 22.0 0.0 0.013 14.7 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat MIT PF04212.18 CRK16850.1 - 0.00061 19.8 0.9 11 6.2 0.1 4.5 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 CRK16850.1 - 0.0011 18.7 8.0 0.021 14.7 0.2 4.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_3 PF07720.12 CRK16850.1 - 0.023 14.7 0.0 11 6.1 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1641 PF07849.11 CRK16850.1 - 0.045 13.6 0.2 0.084 12.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) BTAD PF03704.17 CRK16850.1 - 0.62 10.5 3.2 32 5.0 0.1 3.1 2 1 1 3 3 3 0 Bacterial transcriptional activator domain GFO_IDH_MocA PF01408.22 CRK16852.1 - 3.9e-17 63.2 0.1 6.5e-17 62.5 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 CRK16852.1 - 0.023 15.4 0.2 0.036 14.7 0.2 1.3 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Sugar_tr PF00083.24 CRK16854.1 - 1.5e-56 192.2 1.2 1.7e-56 192.0 1.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK16854.1 - 7.1e-14 51.5 9.2 8.7e-14 51.2 9.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 CRK16854.1 - 0.00095 17.7 2.0 0.0011 17.5 2.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Septin PF00735.18 CRK16855.1 - 3e-115 384.3 0.3 4.4e-115 383.8 0.3 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 CRK16855.1 - 2.1e-07 31.0 0.0 4.3e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CRK16855.1 - 4.2e-06 26.8 1.7 2.2e-05 24.4 0.0 2.6 3 0 0 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 CRK16855.1 - 4.5e-06 26.3 3.3 9.5e-05 22.0 0.1 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 CRK16855.1 - 0.0016 18.7 0.9 0.0045 17.3 0.1 2.2 2 1 0 2 2 2 1 AAA domain Roc PF08477.13 CRK16855.1 - 0.0036 17.5 0.1 0.0078 16.4 0.1 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Pox_A32 PF04665.12 CRK16855.1 - 0.0038 16.7 0.1 0.0078 15.7 0.1 1.5 1 0 0 1 1 1 1 Poxvirus A32 protein AIG1 PF04548.16 CRK16855.1 - 0.0074 15.6 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 AIG1 family AAA_25 PF13481.6 CRK16855.1 - 0.0075 15.9 0.2 0.035 13.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.14 CRK16855.1 - 0.012 14.8 0.0 0.019 14.2 0.0 1.6 1 1 0 1 1 1 0 KAP family P-loop domain AAA_16 PF13191.6 CRK16855.1 - 0.014 15.8 1.6 0.047 14.1 0.1 2.6 2 1 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.6 CRK16855.1 - 0.014 15.1 0.0 0.028 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain IIGP PF05049.13 CRK16855.1 - 0.016 14.3 0.0 0.029 13.4 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Ras PF00071.22 CRK16855.1 - 0.02 14.5 0.5 0.062 12.9 0.5 1.9 2 1 0 2 2 1 0 Ras family ABC_tran PF00005.27 CRK16855.1 - 0.026 15.0 0.2 0.088 13.3 0.0 2.0 2 0 0 2 2 2 0 ABC transporter Casc1_N PF15927.5 CRK16855.1 - 0.03 14.0 11.4 0.081 12.6 11.4 1.7 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus NACHT PF05729.12 CRK16855.1 - 0.051 13.5 0.0 0.099 12.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain FOXP-CC PF16159.5 CRK16855.1 - 0.058 14.0 1.0 0.058 14.0 1.0 2.6 2 1 1 3 3 2 0 FOXP coiled-coil domain T2SSE PF00437.20 CRK16855.1 - 0.058 12.4 0.4 0.26 10.3 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein RNA_helicase PF00910.22 CRK16855.1 - 0.12 12.7 0.0 0.43 11.0 0.0 2.0 2 0 0 2 2 1 0 RNA helicase PduV-EutP PF10662.9 CRK16855.1 - 0.13 12.0 0.4 8.3 6.1 0.1 2.7 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 CRK16855.1 - 0.44 10.6 6.9 4.3 7.4 0.1 3.2 2 1 1 3 3 3 0 Dynamin family Ribosomal_L6e PF01159.19 CRK16855.1 - 1.3 9.5 6.6 7.9 7.1 0.2 3.3 3 0 0 3 3 3 0 Ribosomal protein L6e FUSC PF04632.12 CRK16855.1 - 3.6 6.0 3.8 5.2 5.5 3.8 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family AAA_11 PF13086.6 CRK16855.1 - 4.8 6.9 7.6 22 4.7 0.1 2.2 2 0 0 2 2 2 0 AAA domain Questin_oxidase PF14027.6 CRK16857.1 - 6e-86 289.1 0.3 7.4e-86 288.8 0.3 1.1 1 0 0 1 1 1 1 Questin oxidase-like GP68 PF17469.2 CRK16857.1 - 0.086 13.3 0.0 0.22 11.9 0.0 1.6 1 0 0 1 1 1 0 Phage protein Gp68 NAP PF00956.18 CRK16858.1 - 1.2e-24 87.0 1.0 1.5e-20 73.5 0.0 2.2 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) Zn_clus PF00172.18 CRK16859.1 - 4.8e-08 33.0 12.1 9e-08 32.1 12.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 CRK16859.1 - 8.2e-05 21.6 0.2 0.0002 20.3 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain NACHT_N PF17100.5 CRK16860.1 - 1.2e-38 133.2 0.3 1.2e-38 133.2 0.3 1.9 2 0 0 2 2 2 1 N-terminal domain of NWD NACHT-NTPase AAA_16 PF13191.6 CRK16860.1 - 3.8e-07 30.6 0.5 1.4e-06 28.8 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 CRK16860.1 - 9.8e-05 22.3 0.0 0.00048 20.1 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 CRK16860.1 - 0.00035 20.9 0.2 0.0014 18.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 CRK16860.1 - 0.046 14.2 0.1 1.5 9.4 0.0 2.9 3 0 0 3 3 3 0 ABC transporter KAP_NTPase PF07693.14 CRK16860.1 - 0.12 11.6 0.0 2.3 7.4 0.0 2.4 1 1 1 2 2 2 0 KAP family P-loop domain AAA PF00004.29 CRK16860.1 - 0.15 12.5 0.0 0.57 10.6 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Chlorovi_GP_rpt PF06598.11 CRK16861.1 - 0.14 12.3 0.5 0.14 12.3 0.5 2.1 2 0 0 2 2 2 0 Chlorovirus glycoprotein repeat EBP PF05241.12 CRK16862.1 - 6.3e-73 244.0 12.4 7.3e-73 243.8 12.4 1.0 1 0 0 1 1 1 1 Emopamil binding protein HemY_N PF07219.13 CRK16862.1 - 1.3 9.2 7.1 0.77 10.0 0.6 2.4 2 0 0 2 2 2 0 HemY protein N-terminus S1-P1_nuclease PF02265.16 CRK16863.1 - 1.8e-49 168.8 0.0 2.1e-49 168.7 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease S1-P1_nuclease PF02265.16 CRK16865.1 - 3.9e-34 118.6 0.0 4.3e-34 118.5 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease DUF5083 PF16890.5 CRK16866.1 - 0.99 9.1 4.2 0.54 10.0 1.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5083) PAP2 PF01569.21 CRK16867.1 - 3.3e-14 52.8 8.3 7.3e-14 51.7 6.4 2.3 1 1 0 1 1 1 1 PAP2 superfamily UbiA PF01040.18 CRK16867.1 - 0.0051 16.2 9.5 0.0051 16.2 9.5 2.2 1 1 0 2 2 2 1 UbiA prenyltransferase family Chorion_2 PF03964.15 CRK16867.1 - 0.01 16.7 0.7 0.018 15.8 0.7 1.4 1 0 0 1 1 1 0 Chorion family 2 DUF212 PF02681.14 CRK16867.1 - 0.017 15.2 0.0 0.46 10.6 0.0 2.3 2 0 0 2 2 2 0 Divergent PAP2 family RWD PF05773.22 CRK16868.1 - 0.11 12.7 0.0 0.12 12.7 0.0 1.1 1 0 0 1 1 1 0 RWD domain IBR PF01485.21 CRK16869.1 - 1.7e-18 66.6 35.0 1.3e-14 54.2 4.7 3.8 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain RWD PF05773.22 CRK16869.1 - 8.5e-14 51.8 0.0 1.5e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.6 CRK16869.1 - 0.0044 17.3 6.8 0.0044 17.3 6.8 4.0 3 1 1 4 4 4 1 Ring finger domain zf-C3HC4 PF00097.25 CRK16869.1 - 0.0072 16.2 5.0 0.0072 16.2 5.0 3.9 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CRK16869.1 - 0.01 15.9 4.2 0.01 15.9 4.2 3.7 3 0 0 3 3 3 0 RING-type zinc-finger NDT80_PhoG PF05224.12 CRK16870.1 - 7e-63 212.2 0.0 1.1e-32 113.8 0.0 2.5 2 0 0 2 2 2 2 NDT80 / PhoG like DNA-binding family DUF2011 PF09428.10 CRK16871.1 - 7.5e-23 80.6 0.0 2.3e-22 79.0 0.0 1.9 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2011) Ribosomal_60s PF00428.19 CRK16871.1 - 0.0026 18.3 5.2 0.0026 18.3 5.2 3.6 3 1 0 3 3 3 1 60s Acidic ribosomal protein GTP_EFTU PF00009.27 CRK16872.1 - 1e-56 191.6 0.2 1.4e-56 191.1 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CRK16872.1 - 9.3e-26 90.3 0.0 1.9e-25 89.4 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CRK16872.1 - 6.6e-15 55.3 4.3 6.6e-15 55.3 4.3 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CRK16872.1 - 2.1e-05 24.6 0.0 4.1e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CRK16872.1 - 0.0016 18.4 0.0 0.0043 17.0 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase cobW PF02492.19 CRK16872.1 - 0.042 13.4 0.4 0.25 10.9 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 CRK16872.1 - 0.11 12.3 0.1 15 5.3 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Ribosomal_S14 PF00253.21 CRK16874.1 - 1.3e-14 53.7 3.5 1.4e-14 53.5 3.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e ZZ PF00569.17 CRK16874.1 - 0.24 11.3 4.0 2 8.3 4.0 2.0 1 1 0 1 1 1 0 Zinc finger, ZZ type Thioredoxin PF00085.20 CRK16876.1 - 2.9e-56 187.8 0.0 2.9e-29 101.1 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 CRK16876.1 - 7.2e-20 71.7 0.4 2.3e-19 70.1 0.4 1.9 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain OST3_OST6 PF04756.13 CRK16876.1 - 4e-16 59.2 0.0 1.3e-07 31.3 0.0 2.2 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 CRK16876.1 - 1.2e-13 51.4 0.0 3.9e-07 30.5 0.0 2.8 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CRK16876.1 - 4e-08 33.5 0.0 0.0046 17.3 0.0 3.4 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_7 PF13899.6 CRK16876.1 - 3.3e-07 30.4 0.0 0.026 14.7 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.21 CRK16876.1 - 1.8e-06 27.9 0.1 0.066 13.1 0.0 2.4 1 1 0 2 2 2 2 AhpC/TSA family TraF PF13728.6 CRK16876.1 - 6.1e-05 22.9 0.0 0.21 11.4 0.0 2.4 2 0 0 2 2 2 2 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 CRK16876.1 - 8.1e-05 22.4 0.0 0.036 13.8 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Glutaredoxin PF00462.24 CRK16876.1 - 0.0014 18.8 1.0 1.6 9.0 0.1 3.4 2 2 0 2 2 2 2 Glutaredoxin HyaE PF07449.11 CRK16876.1 - 0.0067 16.4 0.0 0.063 13.2 0.0 2.3 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE Thioredoxin_6 PF13848.6 CRK16876.1 - 0.0082 16.1 0.0 0.11 12.4 0.0 2.7 1 1 1 2 2 2 1 Thioredoxin-like domain Thioredoxin_3 PF13192.6 CRK16876.1 - 0.015 15.3 0.0 3.1 7.9 0.0 2.7 2 0 0 2 2 2 0 Thioredoxin domain FA_desaturase_2 PF03405.14 CRK16876.1 - 0.056 12.3 0.1 0.076 11.8 0.1 1.2 1 0 0 1 1 1 0 Fatty acid desaturase YABBY PF04690.13 CRK16876.1 - 0.16 12.5 0.0 19 5.7 0.0 2.7 3 0 0 3 3 3 0 YABBY protein Thioredoxin_4 PF13462.6 CRK16876.1 - 0.21 11.7 8.3 10 6.3 0.1 4.2 3 2 1 4 4 4 0 Thioredoxin HSBP1 PF06825.12 CRK16877.1 - 1.4e-15 56.9 0.2 1.5e-15 56.8 0.2 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Baculo_PEP_C PF04513.12 CRK16877.1 - 0.024 14.7 0.1 0.03 14.4 0.1 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus zf-rbx1 PF12678.7 CRK16878.1 - 1.3e-09 38.2 1.0 2.2e-09 37.4 1.0 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CRK16878.1 - 1.5e-08 34.9 5.8 4.9e-08 33.2 2.1 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 CRK16878.1 - 1.7e-08 34.2 1.0 2.7e-08 33.6 1.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CRK16878.1 - 1.3e-07 31.3 7.0 7.1e-06 25.8 2.2 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CRK16878.1 - 4.1e-07 29.8 0.7 7.3e-07 29.0 0.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CRK16878.1 - 2.1e-06 27.6 1.2 7.4e-06 25.9 0.3 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CRK16878.1 - 5.7e-05 22.9 4.4 9.8e-05 22.1 1.3 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CRK16878.1 - 0.00013 21.7 0.6 0.00013 21.7 0.6 1.6 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 CRK16878.1 - 0.0014 18.3 8.0 0.0044 16.7 0.3 2.8 3 0 0 3 3 3 2 RING-like zinc finger Zn_ribbon_17 PF17120.5 CRK16878.1 - 0.0053 16.3 0.5 0.012 15.2 0.5 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 CRK16878.1 - 0.015 15.3 0.6 0.04 14.0 0.6 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 CRK16878.1 - 6 7.1 5.9 32 4.8 5.9 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain NAD_kinase PF01513.21 CRK16879.1 - 3.2e-70 236.6 0.0 1.6e-69 234.3 0.0 1.9 1 1 0 1 1 1 1 ATP-NAD kinase Voldacs PF03517.13 CRK16879.1 - 0.079 13.1 0.1 0.19 11.8 0.1 1.6 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling DUF3402 PF11882.8 CRK16880.1 - 7.4e-202 671.5 0.0 1.2e-201 670.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.13 CRK16880.1 - 3.5e-89 298.8 0.2 5.1e-89 298.3 0.2 1.2 1 0 0 1 1 1 1 N1221-like protein RCR PF12273.8 CRK16881.1 - 8.9e-05 23.1 0.2 0.00025 21.7 0.2 1.7 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red MARVEL PF01284.23 CRK16881.1 - 0.00017 21.7 18.3 0.0048 16.9 19.3 2.1 1 1 1 2 2 2 2 Membrane-associating domain SUR7 PF06687.12 CRK16881.1 - 0.45 10.1 0.0 0.45 10.1 0.0 2.2 2 0 0 2 2 2 0 SUR7/PalI family DUF3422 PF11902.8 CRK16881.1 - 1.1 8.4 2.0 27 3.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3422) WSC PF01822.19 CRK16882.1 - 1.9e-71 236.3 55.3 2.1e-19 69.5 7.9 4.5 4 0 0 4 4 4 4 WSC domain peroxidase PF00141.23 CRK16882.1 - 2.6e-23 82.9 0.1 6.2e-23 81.7 0.1 1.6 1 0 0 1 1 1 1 Peroxidase Las1 PF04031.13 CRK16885.1 - 9.5e-96 318.0 0.3 2.1e-61 206.5 0.2 2.1 2 0 0 2 2 2 2 Las1-like Bacteroid_pep PF14406.6 CRK16885.1 - 0.026 14.9 0.2 12 6.3 0.1 2.4 2 0 0 2 2 2 0 Ribosomally synthesized peptide in Bacteroidetes FliG_N PF14842.6 CRK16885.1 - 0.048 14.2 0.3 18 6.0 0.0 3.1 2 2 1 3 3 3 0 FliG N-terminal domain EF-hand_8 PF13833.6 CRK16886.1 - 0.0096 15.8 0.0 3.2 7.7 0.0 3.2 3 1 0 3 3 3 2 EF-hand domain pair IF4E PF01652.18 CRK16887.1 - 5.7e-35 120.4 0.0 7.4e-35 120.1 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF3437 PF11919.8 CRK16888.1 - 0.029 14.3 0.3 0.12 12.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) RNA_pol_A_bac PF01000.26 CRK16891.1 - 6.6e-32 110.2 0.0 1.7e-31 108.9 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 CRK16891.1 - 1.9e-06 27.2 0.0 2.9e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain 14-3-3 PF00244.20 CRK16893.1 - 1.1e-53 182.1 1.7 1.6e-53 181.4 1.7 1.4 1 1 0 1 1 1 1 14-3-3 protein Nsp1_C PF05064.13 CRK16893.1 - 2e-14 53.3 1.3 4.9e-14 52.1 1.3 1.6 1 0 0 1 1 1 1 Nsp1-like C-terminal region TPR_19 PF14559.6 CRK16893.1 - 0.069 13.7 2.0 0.64 10.6 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat L27_N PF09060.10 CRK16893.1 - 0.12 12.5 1.5 11 6.2 0.1 2.5 2 0 0 2 2 2 0 L27_N V-SNARE PF05008.15 CRK16893.1 - 2.9 8.4 6.7 0.45 10.9 0.7 2.6 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus C2 PF00168.30 CRK16894.1 - 7.4e-14 51.9 0.0 1.3e-07 31.8 0.0 2.2 2 0 0 2 2 2 2 C2 domain MFS_1 PF07690.16 CRK16896.1 - 2.3e-15 56.4 4.8 2.8e-15 56.1 4.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Drf_GBD PF06371.13 CRK16896.1 - 0.0016 18.0 0.1 0.0023 17.6 0.1 1.2 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain AIDA PF16168.5 CRK16918.1 - 0.053 13.6 0.2 0.09 12.9 0.2 1.3 1 0 0 1 1 1 0 Adhesin of bacterial autotransporter system, probable stalk Efg1 PF10153.9 CRK16934.1 - 0.087 13.2 0.0 0.11 12.9 0.0 1.1 1 0 0 1 1 1 0 rRNA-processing protein Efg1 FF PF01846.19 CRK16935.1 - 2.6e-52 174.8 12.4 1.5e-14 53.9 0.0 7.1 6 1 0 6 6 6 6 FF domain RhoGAP-FF1 PF16512.5 CRK16935.1 - 0.0042 17.7 8.9 4.4 8.0 0.1 4.6 3 2 1 4 4 4 2 p190-A and -B Rho GAPs FF domain Lipin_mid PF16876.5 CRK16935.1 - 0.02 15.0 1.0 1.6 8.9 0.7 3.0 1 1 1 2 2 2 0 Lipin/Ned1/Smp2 multi-domain protein middle domain HycH PF07450.11 CRK16935.1 - 0.13 12.6 0.1 0.58 10.5 0.1 2.1 1 1 0 1 1 1 0 Formate hydrogenlyase maturation protein HycH KinB_sensor PF16767.5 CRK16935.1 - 0.34 11.4 7.1 5.4 7.5 0.7 4.0 4 0 0 4 4 4 0 Sensor domain of alginate biosynthesis sensor protein KinB Cytochrom_B562 PF07361.11 CRK16935.1 - 2.7 8.7 9.0 1.3 9.8 1.6 3.6 4 1 0 4 4 4 0 Cytochrome b562 adh_short_C2 PF13561.6 CRK16937.1 - 6.4e-45 153.5 0.0 8.1e-45 153.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Citrate_synt PF00285.21 CRK16937.1 - 1.1e-32 113.5 0.0 1.6e-32 113.0 0.0 1.2 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain adh_short PF00106.25 CRK16937.1 - 3.4e-23 82.1 0.0 4.6e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase RecC_C PF17946.1 CRK16937.1 - 0.051 13.4 0.1 0.08 12.7 0.1 1.2 1 0 0 1 1 1 0 RecC C-terminal domain Fungal_trans PF04082.18 CRK16939.1 - 1.2e-10 40.9 0.1 3e-10 39.6 0.1 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK16939.1 - 4e-06 26.8 10.6 4e-06 26.8 10.6 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain OCD_Mu_crystall PF02423.15 CRK16940.1 - 1.5e-11 43.8 0.2 3.4e-10 39.4 0.2 2.1 1 1 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 CRK16940.1 - 0.00037 20.6 0.0 0.0099 16.0 0.0 2.2 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase BATS PF06968.13 CRK16941.1 - 5.5e-23 80.9 0.1 1.5e-22 79.6 0.1 1.8 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 CRK16941.1 - 2.7e-14 53.9 0.1 4.9e-14 53.1 0.1 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Abhydrolase_1 PF00561.20 CRK16942.1 - 3.9e-24 85.7 0.0 1.4e-23 83.9 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 CRK16942.1 - 2.4e-20 72.6 0.3 3.4e-19 68.9 0.1 2.8 2 1 1 3 3 3 1 TAP-like protein Pro_dh PF01619.18 CRK16943.1 - 2.1e-60 204.8 0.0 2.5e-60 204.5 0.0 1.1 1 0 0 1 1 1 1 Proline dehydrogenase Sugar_tr PF00083.24 CRK16944.1 - 8.1e-23 81.0 0.0 9.1e-17 61.0 0.0 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CRK16944.1 - 0.44 9.4 5.4 0.49 9.3 3.6 1.7 1 1 0 1 1 1 0 Major Facilitator Superfamily Amidohydro_1 PF01979.20 CRK16946.1 - 2.3e-24 86.4 0.0 6.7e-14 52.0 0.0 2.3 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 CRK16946.1 - 5e-15 55.9 0.4 2.1e-08 34.1 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family AalphaY_MDB PF04611.12 CRK16946.1 - 0.039 14.0 0.0 0.094 12.7 0.0 1.6 1 0 0 1 1 1 0 Mating type protein A alpha Y mating type dependent binding region polyprenyl_synt PF00348.17 CRK16947.1 - 1.9e-100 335.1 0.0 8e-65 218.4 0.0 2.2 2 0 0 2 2 2 2 Polyprenyl synthetase Amidohydro_1 PF01979.20 CRK16947.1 - 2.3e-12 46.9 0.0 4.1e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase family HEPPP_synt_1 PF07307.11 CRK16947.1 - 3.3e-06 26.9 0.0 0.064 12.9 0.0 2.2 2 0 0 2 2 2 2 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Amidohydro_3 PF07969.11 CRK16947.1 - 0.00036 20.1 0.2 0.00057 19.5 0.2 1.3 1 0 0 1 1 1 1 Amidohydrolase family AAA_lid_8 PF17868.1 CRK16947.1 - 0.011 15.6 0.0 9.2 6.2 0.0 2.6 2 0 0 2 2 2 0 AAA lid domain HEAT_PBS PF03130.16 CRK16947.1 - 0.3 11.9 4.9 27 5.8 0.3 3.5 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat Vma12 PF11712.8 CRK16948.1 - 4.2e-46 156.5 0.0 7.1e-46 155.7 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF1772 PF08592.11 CRK16948.1 - 0.02 15.2 0.2 0.042 14.2 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) DUF2681 PF10883.8 CRK16948.1 - 0.17 12.3 0.3 0.17 12.3 0.3 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2681) ABC_tran_Xtn PF12848.7 CRK16948.1 - 1.4 9.0 6.2 10 6.2 0.1 2.8 3 0 0 3 3 3 0 ABC transporter 2OG-FeII_Oxy_3 PF13640.6 CRK16949.1 - 2.6e-09 37.9 0.0 4.5e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 CRK16952.1 - 1.7e-31 109.5 31.7 1.7e-31 109.5 31.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF5455 PF17537.2 CRK16952.1 - 0.56 10.6 0.0 0.56 10.6 0.0 3.7 4 0 0 4 4 4 0 Family of unknown function (DUF5455) p450 PF00067.22 CRK16953.1 - 2e-34 119.2 0.1 6.2e-19 68.1 0.0 2.4 2 1 0 2 2 2 2 Cytochrome P450 RE_HaeIII PF09556.10 CRK16953.1 - 0.01 15.0 0.1 2 7.5 0.0 2.2 2 0 0 2 2 2 0 HaeIII restriction endonuclease Sugar_tr PF00083.24 CRK16954.1 - 1.1e-117 393.6 23.0 1.3e-117 393.4 23.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK16954.1 - 1.3e-22 80.2 31.0 8e-21 74.3 21.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sulfatase PF00884.23 CRK16955.1 - 3e-66 223.9 0.1 4.4e-66 223.4 0.1 1.2 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 CRK16955.1 - 2.3e-21 76.0 6.7 2.4e-20 72.7 6.7 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4976) Phosphodiest PF01663.22 CRK16955.1 - 4.8e-07 29.7 5.8 2.3e-06 27.4 3.1 2.6 2 1 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 CRK16955.1 - 0.0022 16.7 0.1 0.0057 15.3 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Ricin_B_lectin PF00652.22 CRK16955.1 - 0.14 12.4 0.1 0.81 10.0 0.1 2.1 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin domain Fungal_trans PF04082.18 CRK16956.1 - 2e-06 27.0 0.1 2.8e-06 26.6 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_3 PF00933.21 CRK16957.1 - 3.1e-49 168.1 0.0 3.9e-49 167.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 CRK16957.1 - 9.4e-39 133.5 0.0 2.2e-38 132.3 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 CRK16957.1 - 5.6e-17 61.6 0.0 1.1e-16 60.7 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Prefoldin_2 PF01920.20 CRK16958.1 - 2.4e-16 59.6 11.2 3.2e-16 59.2 11.2 1.3 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.17 CRK16958.1 - 0.0081 16.1 1.1 0.0081 16.1 1.1 2.1 2 0 0 2 2 2 1 Prefoldin subunit ATP-synt_E_2 PF08112.11 CRK16958.1 - 0.052 13.8 2.4 2.4 8.5 1.0 2.9 2 1 1 3 3 3 0 ATP synthase epsilon subunit Bcr-Abl_Oligo PF09036.10 CRK16958.1 - 0.075 13.1 1.2 0.41 10.7 0.1 2.1 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain EFG_C PF00679.24 CRK16958.1 - 0.082 13.0 0.6 1.6 8.8 0.1 2.1 2 0 0 2 2 2 0 Elongation factor G C-terminus Fib_alpha PF08702.10 CRK16958.1 - 0.12 12.6 5.4 0.17 12.1 1.1 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Spc24 PF08286.11 CRK16958.1 - 0.19 12.0 6.2 1.1 9.6 0.4 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 HSBP1 PF06825.12 CRK16958.1 - 0.26 11.2 3.0 0.41 10.5 0.1 2.3 2 0 0 2 2 2 0 Heat shock factor binding protein 1 TMPIT PF07851.13 CRK16958.1 - 0.28 10.4 4.1 0.37 10.0 4.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF4407 PF14362.6 CRK16958.1 - 0.59 9.4 8.8 0.9 8.8 8.8 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 CRK16958.1 - 0.77 8.6 12.2 2.1 7.1 12.2 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein FlaC_arch PF05377.11 CRK16958.1 - 1.6 9.2 3.6 15 6.1 0.2 2.9 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) TPR_MLP1_2 PF07926.12 CRK16958.1 - 7 6.7 16.2 5.1 7.2 5.4 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF16 PF01519.16 CRK16958.1 - 9.8 6.7 14.3 0.44 11.1 4.0 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 AAA PF00004.29 CRK16959.1 - 2.4e-42 144.5 0.0 4.6e-42 143.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 CRK16959.1 - 5.9e-25 87.0 0.5 2e-24 85.3 0.5 2.0 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 CRK16959.1 - 1.7e-22 79.2 5.2 1.7e-22 79.2 5.2 1.9 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain RuvB_N PF05496.12 CRK16959.1 - 1.5e-06 28.0 0.0 2.8e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CRK16959.1 - 3.4e-06 27.6 0.0 0.0014 19.0 0.0 2.9 2 1 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 CRK16959.1 - 3.1e-05 24.0 0.0 0.00015 21.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 CRK16959.1 - 5.3e-05 23.0 0.0 0.00012 21.9 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 CRK16959.1 - 0.0001 21.6 0.0 0.00024 20.4 0.0 1.5 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 CRK16959.1 - 0.00013 22.2 0.2 0.019 15.2 0.0 2.7 2 1 0 3 3 2 1 AAA domain AAA_14 PF13173.6 CRK16959.1 - 0.00025 21.1 0.0 0.00062 19.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 CRK16959.1 - 0.00025 20.3 0.0 0.00087 18.5 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_2 PF07724.14 CRK16959.1 - 0.00027 21.1 0.0 0.0021 18.2 0.0 2.3 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 CRK16959.1 - 0.00035 20.9 0.4 0.01 16.2 0.0 3.2 4 0 0 4 4 3 1 RNA helicase ATPase PF06745.13 CRK16959.1 - 0.0006 19.2 0.0 6.4 6.0 0.0 3.3 2 1 1 3 3 3 0 KaiC AAA_33 PF13671.6 CRK16959.1 - 0.00073 19.7 0.0 0.0038 17.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 CRK16959.1 - 0.0008 19.2 0.1 0.0047 16.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CRK16959.1 - 0.00085 19.9 0.0 0.0032 18.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 CRK16959.1 - 0.0079 16.6 0.6 0.025 15.0 0.0 2.2 3 1 0 3 3 2 1 AAA domain NACHT PF05729.12 CRK16959.1 - 0.0081 16.1 0.0 0.67 9.9 0.0 2.4 1 1 1 2 2 2 1 NACHT domain AAA_7 PF12775.7 CRK16959.1 - 0.0089 15.6 0.0 0.073 12.6 0.0 2.3 2 1 0 2 2 2 1 P-loop containing dynein motor region AAA_25 PF13481.6 CRK16959.1 - 0.0089 15.6 0.2 0.5 9.9 0.1 2.6 2 1 0 3 3 3 1 AAA domain USP8_dimer PF08969.11 CRK16959.1 - 0.019 15.2 3.0 0.019 15.2 3.0 1.9 2 0 0 2 2 2 0 USP8 dimerisation domain Mg_chelatase PF01078.21 CRK16959.1 - 0.037 13.4 0.0 0.079 12.3 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Parvo_NS1 PF01057.17 CRK16959.1 - 0.041 13.0 0.0 0.082 12.0 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PhoH PF02562.16 CRK16959.1 - 0.07 12.6 0.1 0.15 11.5 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein ATPase_2 PF01637.18 CRK16959.1 - 0.12 12.2 1.0 1.2 9.0 0.0 2.6 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea AFG1_ATPase PF03969.16 CRK16959.1 - 0.13 11.1 0.0 0.24 10.2 0.0 1.4 1 0 0 1 1 1 0 AFG1-like ATPase Torsin PF06309.11 CRK16959.1 - 0.14 12.2 0.0 0.46 10.6 0.0 1.8 2 0 0 2 2 1 0 Torsin AAA_21 PF13304.6 CRK16959.1 - 0.16 11.7 0.1 10 5.8 0.0 2.3 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Nop PF01798.18 CRK16960.1 - 9.6e-51 172.5 0.0 2.8e-42 144.8 0.0 2.4 1 1 1 2 2 2 2 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 CRK16960.1 - 1.2e-16 60.8 0.0 1.2e-16 60.8 0.0 2.2 2 0 0 2 2 2 1 NOP5NT (NUC127) domain RNA_polI_A34 PF08208.11 CRK16960.1 - 0.74 9.9 24.0 1.4 9.0 24.0 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 BEX PF04538.12 CRK16960.1 - 2.5 8.7 17.2 5 7.7 17.2 1.5 1 0 0 1 1 1 0 Brain expressed X-linked like family CP2 PF04516.15 CRK16962.1 - 1.4e-82 276.5 0.0 3.1e-82 275.3 0.0 1.5 2 0 0 2 2 2 1 CP2 transcription factor Tektin PF03148.14 CRK16962.1 - 0.023 13.5 0.0 0.035 12.8 0.0 1.2 1 0 0 1 1 1 0 Tektin family TMF_DNA_bd PF12329.8 CRK16962.1 - 0.041 13.9 0.7 0.086 12.8 0.7 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding AKNA PF12443.8 CRK16962.1 - 0.09 13.4 0.2 0.52 11.0 0.2 2.4 1 0 0 1 1 1 0 AT-hook-containing transcription factor Oxysterol_BP PF01237.18 CRK16963.1 - 2.3e-48 164.9 0.0 5.2e-46 157.2 0.0 2.2 1 1 0 1 1 1 1 Oxysterol-binding protein MAM33 PF02330.16 CRK16964.1 - 5.3e-74 248.7 3.4 2e-73 246.9 3.4 1.7 1 1 0 1 1 1 1 Mitochondrial glycoprotein Glyco_hydro_43 PF04616.14 CRK16965.1 - 1.3e-63 215.0 2.4 1.8e-63 214.6 2.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 CRK16965.1 - 7.6e-19 68.2 0.0 1.7e-18 67.1 0.0 1.5 2 0 0 2 2 2 1 Beta xylosidase C-terminal Concanavalin A-like domain DUF5597 PF18120.1 CRK16966.1 - 3.4e-27 95.2 0.1 5.6e-27 94.5 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5597) Glyco_hydro_42 PF02449.15 CRK16966.1 - 0.00016 21.2 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 Beta-galactosidase Sugar_tr PF00083.24 CRK16967.1 - 1.9e-38 132.5 0.1 3.3e-27 95.5 0.0 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CRK16967.1 - 4.6e-09 35.7 4.5 7.4e-05 21.8 3.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 CRK16967.1 - 0.04 12.5 0.7 0.14 10.7 0.1 1.9 2 0 0 2 2 2 0 MFS/sugar transport protein Helicase_C PF00271.31 CRK16968.1 - 4.9e-07 30.1 0.0 1.3e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TruD PF01142.18 CRK16969.1 - 2.6e-28 99.0 0.0 3.3e-28 98.6 0.0 1.1 1 0 0 1 1 1 1 tRNA pseudouridine synthase D (TruD) LptE PF04390.12 CRK16969.1 - 0.075 13.7 0.0 0.17 12.6 0.0 1.9 1 1 0 1 1 1 0 Lipopolysaccharide-assembly YcbB PF08664.10 CRK16969.1 - 0.084 12.9 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 YcbB domain Ribosomal_L14e PF01929.17 CRK16970.1 - 5.7e-30 103.6 4.1 7.2e-30 103.3 4.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L14 HMA PF00403.26 CRK16971.1 - 1.1e-06 28.9 0.2 1.3e-06 28.8 0.2 1.0 1 0 0 1 1 1 1 Heavy-metal-associated domain CTU2 PF10288.9 CRK16971.1 - 0.15 12.3 0.0 0.15 12.3 0.0 1.2 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 2-Hacid_dh_C PF02826.19 CRK16974.1 - 1.7e-18 66.6 0.0 4.2e-18 65.3 0.0 1.7 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IQ PF00612.27 CRK16974.1 - 1.7e-07 30.4 11.7 2.5e-05 23.7 0.2 3.6 3 0 0 3 3 3 2 IQ calmodulin-binding motif Spc7 PF08317.11 CRK16974.1 - 0.00061 18.8 14.1 0.00061 18.8 14.1 1.6 1 1 1 2 2 2 1 Spc7 kinetochore protein GAS PF13851.6 CRK16974.1 - 0.00075 18.9 20.4 0.0018 17.7 20.4 1.6 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding Sec34 PF04136.15 CRK16974.1 - 0.0019 18.1 6.3 0.0027 17.6 5.0 1.9 1 1 0 1 1 1 1 Sec34-like family DUF812 PF05667.11 CRK16974.1 - 0.0021 17.1 15.6 0.0026 16.7 15.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Baculo_PEP_C PF04513.12 CRK16974.1 - 0.0042 17.1 8.3 0.011 15.8 8.3 1.8 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus FlaC_arch PF05377.11 CRK16974.1 - 0.027 14.9 9.4 0.1 13.0 0.1 3.0 3 1 0 3 3 2 0 Flagella accessory protein C (FlaC) AAA_13 PF13166.6 CRK16974.1 - 0.028 13.1 11.9 0.04 12.6 11.9 1.3 1 0 0 1 1 1 0 AAA domain CALCOCO1 PF07888.11 CRK16974.1 - 0.03 13.2 17.5 0.035 13.0 17.5 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like TolA_bind_tri PF16331.5 CRK16974.1 - 0.039 14.0 14.0 0.43 10.7 4.9 2.6 1 1 0 2 2 2 0 TolA binding protein trimerisation BRE1 PF08647.11 CRK16974.1 - 0.039 14.0 18.0 0.29 11.2 5.6 2.5 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Seryl_tRNA_N PF02403.22 CRK16974.1 - 0.043 14.0 17.6 0.066 13.4 9.0 2.3 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DivIC PF04977.15 CRK16974.1 - 0.046 13.5 15.2 0.59 9.9 2.6 3.6 2 1 1 3 3 3 0 Septum formation initiator ATG16 PF08614.11 CRK16974.1 - 0.048 13.9 19.5 0.62 10.2 19.2 2.2 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) TMCO5 PF14992.6 CRK16974.1 - 0.062 12.9 14.3 0.08 12.5 14.3 1.1 1 0 0 1 1 1 0 TMCO5 family Jnk-SapK_ap_N PF09744.9 CRK16974.1 - 0.063 13.5 20.5 0.037 14.2 7.4 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DegQ PF08181.11 CRK16974.1 - 0.064 13.4 0.7 0.064 13.4 0.7 2.7 2 0 0 2 2 2 0 DegQ (SacQ) family KASH_CCD PF14662.6 CRK16974.1 - 0.076 12.8 19.8 1.1 9.0 19.7 2.1 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Phage_GP20 PF06810.11 CRK16974.1 - 0.1 12.4 12.2 0.045 13.5 4.7 2.3 1 1 1 2 2 2 0 Phage minor structural protein GP20 BST2 PF16716.5 CRK16974.1 - 0.11 13.2 17.0 0.58 10.8 3.8 2.9 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 Snapin_Pallidin PF14712.6 CRK16974.1 - 0.13 12.7 16.3 0.27 11.7 6.0 2.9 2 1 0 2 2 2 0 Snapin/Pallidin FPP PF05911.11 CRK16974.1 - 0.15 10.3 17.5 0.26 9.4 17.2 1.5 1 1 0 1 1 1 0 Filament-like plant protein, long coiled-coil IQCJ-SCHIP1 PF15157.6 CRK16974.1 - 0.15 11.9 2.9 0.16 11.8 0.2 2.3 1 1 1 2 2 2 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif Atg14 PF10186.9 CRK16974.1 - 0.17 11.0 14.1 0.15 11.2 13.2 1.4 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Tropomyosin_1 PF12718.7 CRK16974.1 - 0.25 11.5 19.5 2.7 8.1 19.5 2.1 1 1 0 1 1 1 0 Tropomyosin like EzrA PF06160.12 CRK16974.1 - 0.27 9.4 17.0 0.16 10.1 2.9 2.0 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Uso1_p115_C PF04871.13 CRK16974.1 - 0.28 11.6 19.8 0.55 10.6 6.9 2.2 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Dna2 PF08696.11 CRK16974.1 - 0.36 10.6 5.4 0.26 11.1 3.6 1.6 1 1 1 2 2 2 0 DNA replication factor Dna2 TPR_MLP1_2 PF07926.12 CRK16974.1 - 0.4 10.7 22.6 0.14 12.2 1.9 2.8 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF5082 PF16888.5 CRK16974.1 - 0.45 10.8 14.5 0.27 11.5 5.8 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) CLZ PF16526.5 CRK16974.1 - 0.49 10.8 12.8 0.29 11.5 1.1 2.8 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Dak2 PF02734.17 CRK16974.1 - 0.63 9.9 3.1 0.74 9.7 1.9 1.7 1 1 1 2 2 2 0 DAK2 domain CENP-F_leu_zip PF10473.9 CRK16974.1 - 0.67 10.0 20.7 33 4.5 20.7 2.2 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CENP-H PF05837.12 CRK16974.1 - 0.79 10.2 19.7 0.63 10.5 6.5 2.5 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Vps51 PF08700.11 CRK16974.1 - 0.88 9.7 9.7 1.8 8.7 0.7 2.9 2 1 0 2 2 2 0 Vps51/Vps67 DUF3450 PF11932.8 CRK16974.1 - 0.88 8.8 18.1 1 8.6 6.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) TMF_TATA_bd PF12325.8 CRK16974.1 - 0.93 9.7 18.2 0.95 9.7 1.8 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Exonuc_VII_L PF02601.15 CRK16974.1 - 0.94 9.0 14.7 3.4 7.2 14.7 1.7 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF1664 PF07889.12 CRK16974.1 - 1 9.4 10.2 2.8 8.0 0.7 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 CRK16974.1 - 1.1 9.6 13.5 8.3 6.8 4.2 3.2 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TMPIT PF07851.13 CRK16974.1 - 1.1 8.4 10.9 1.8 7.7 10.6 1.5 1 1 0 1 1 1 0 TMPIT-like protein NPV_P10 PF05531.12 CRK16974.1 - 1.1 9.7 4.0 11 6.5 0.4 2.8 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Cortex-I_coil PF09304.10 CRK16974.1 - 1.3 9.3 11.8 0.26 11.5 5.0 2.3 1 1 1 2 2 2 0 Cortexillin I, coiled coil VSG_B PF13206.6 CRK16974.1 - 1.9 7.7 10.8 2.5 7.3 10.8 1.2 1 0 0 1 1 1 0 Trypanosomal VSG domain YabA PF06156.13 CRK16974.1 - 2.3 8.9 14.4 6.2 7.5 4.0 2.6 1 1 1 2 2 2 0 Initiation control protein YabA Prominin PF05478.11 CRK16974.1 - 2.3 6.1 12.9 2.6 5.9 4.4 2.1 1 1 1 2 2 2 0 Prominin EMP24_GP25L PF01105.24 CRK16974.1 - 2.9 7.8 14.4 1.2e+02 2.6 14.4 2.2 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF4164 PF13747.6 CRK16974.1 - 2.9 8.2 15.2 0.65 10.3 9.5 2.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) OmpH PF03938.14 CRK16974.1 - 3.4 8.0 20.9 1.5e+02 2.7 20.9 2.5 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) APG6_N PF17675.1 CRK16974.1 - 4 8.0 22.9 3.3e+02 1.8 22.9 2.2 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF2203 PF09969.9 CRK16974.1 - 4.9 7.9 13.0 3.3 8.4 6.7 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Fib_alpha PF08702.10 CRK16974.1 - 5.6 7.2 12.6 9.4 6.4 1.3 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family XhlA PF10779.9 CRK16974.1 - 6.6 7.0 13.4 3.1 8.1 0.8 3.3 1 1 1 2 2 2 0 Haemolysin XhlA DUF5595 PF18077.1 CRK16974.1 - 7 6.8 10.2 7 6.8 1.5 2.8 3 0 0 3 3 2 0 Domain of unknown function (DUF5595) DUF4337 PF14235.6 CRK16974.1 - 7 6.7 11.7 0.28 11.3 3.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) Sec2p PF06428.11 CRK16974.1 - 7.7 6.6 17.9 6.6 6.8 10.3 2.6 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p Tup_N PF08581.10 CRK16974.1 - 7.8 6.9 13.7 1.1 9.7 2.1 2.5 1 1 1 2 2 2 0 Tup N-terminal DUF4665 PF15679.5 CRK16974.1 - 8.2 7.1 10.0 5.5 7.7 3.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4665) Noelin-1 PF12308.8 CRK16974.1 - 9.6 6.3 11.2 0.91 9.5 1.9 2.7 1 1 2 3 3 3 0 Neurogenesis glycoprotein Prp31_C PF09785.9 CRK16975.1 - 3.6e-46 157.0 2.4 6e-46 156.3 2.4 1.4 1 0 0 1 1 1 1 Prp31 C terminal domain Nop PF01798.18 CRK16975.1 - 2.2e-05 24.1 0.1 3.1e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin DUF1910 PF08928.10 CRK16978.1 - 0.041 13.9 0.4 0.16 12.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1910) MNE1 PF13762.6 CRK16978.1 - 0.079 12.9 0.4 1.1 9.3 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial splicing apparatus component OPT PF03169.15 CRK16992.1 - 7.5e-27 94.2 10.0 9.1e-27 94.0 10.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Aminotran_4 PF01063.19 CRK17011.1 - 2e-19 70.3 0.0 2.6e-19 70.0 0.0 1.0 1 0 0 1 1 1 1 Amino-transferase class IV CheD PF03975.13 CRK17020.1 - 0.035 14.2 0.2 0.057 13.5 0.2 1.4 1 0 0 1 1 1 0 CheD chemotactic sensory transduction RRM_1 PF00076.22 CRK17022.1 - 5.6e-05 22.9 0.0 0.00012 21.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_23 PF13476.6 CRK17022.1 - 0.00086 19.9 6.0 0.00098 19.7 6.0 1.1 1 0 0 1 1 1 1 AAA domain DUF4407 PF14362.6 CRK17022.1 - 0.21 10.9 3.0 0.23 10.8 3.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TMPIT PF07851.13 CRK17022.1 - 0.3 10.3 6.3 0.4 9.9 6.3 1.1 1 0 0 1 1 1 0 TMPIT-like protein CENP-Q PF13094.6 CRK17022.1 - 1.2 9.3 15.7 0.2 11.8 11.2 1.8 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF501 PF04417.12 CRK17022.1 - 1.7 8.4 5.4 3 7.7 5.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF501) V_ATPase_I PF01496.19 CRK17022.1 - 3.2 5.5 5.3 3.7 5.3 5.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Pkinase PF00069.25 CRK17023.1 - 7.7e-17 61.5 0.0 1.2e-16 60.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK17023.1 - 4.6e-16 58.9 0.0 7e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase ADH_zinc_N_2 PF13602.6 CRK17024.1 - 8.6e-28 98.0 0.2 1.4e-27 97.4 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 CRK17024.1 - 5.5e-14 52.3 1.7 1.3e-13 51.1 1.0 1.9 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CRK17024.1 - 2.7e-05 24.0 0.0 9.5e-05 22.2 0.0 2.0 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Amidohydro_1 PF01979.20 CRK17025.1 - 3e-20 72.8 1.8 7.8e-17 61.6 0.1 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 CRK17025.1 - 5.1e-10 39.4 2.5 1.2e-08 34.9 0.3 2.1 2 0 0 2 2 2 2 Amidohydrolase family Arrestin_N PF00339.29 CRK17026.1 - 0.051 13.6 0.0 0.11 12.6 0.0 1.6 1 1 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain TPR_2 PF07719.17 CRK17027.1 - 5.3e-09 35.5 1.2 0.0002 21.2 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 CRK17027.1 - 3.3e-05 23.5 0.1 0.071 13.0 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 CRK17027.1 - 4.9e-05 23.9 0.5 0.00089 19.9 1.0 2.4 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 CRK17027.1 - 0.00011 22.4 1.0 0.0045 17.2 1.1 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 CRK17027.1 - 0.00015 21.7 0.0 0.0021 18.2 0.0 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 CRK17027.1 - 0.0015 19.0 1.2 0.0092 16.5 0.1 2.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 CRK17027.1 - 0.041 13.9 0.4 29 5.0 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 CRK17027.1 - 0.044 14.4 9.1 0.07 13.8 2.8 3.1 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 CRK17027.1 - 0.06 14.2 5.0 0.14 13.1 1.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 CRK17027.1 - 0.14 12.9 1.3 0.62 10.8 0.1 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat RAMA PF18755.1 CRK17029.1 - 0.0068 16.8 0.1 0.044 14.2 0.0 2.3 2 0 0 2 2 2 1 Restriction Enzyme Adenine Methylase Associated Zn_clus PF00172.18 CRK17029.1 - 0.035 14.2 5.7 0.066 13.3 5.7 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain TauD PF02668.16 CRK17030.1 - 1.7e-24 87.1 0.0 3.1e-24 86.2 0.0 1.4 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 CRK17030.1 - 0.0035 16.5 0.0 0.0057 15.8 0.0 1.2 1 0 0 1 1 1 1 CsiD TauD PF02668.16 CRK17031.1 - 2.2e-22 80.1 0.0 4.7e-22 79.1 0.0 1.5 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 CRK17031.1 - 0.00082 18.6 0.0 0.0013 18.0 0.0 1.2 1 0 0 1 1 1 1 CsiD NMT1 PF09084.11 CRK17036.1 - 5.3e-80 268.4 0.0 6.7e-80 268.1 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 CRK17036.1 - 2.5e-06 27.4 0.3 0.21 11.2 0.0 3.3 3 1 0 3 3 3 2 NMT1-like family Phosphonate-bd PF12974.7 CRK17036.1 - 0.036 13.7 0.0 0.061 12.9 0.0 1.3 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein PBP_like PF12727.7 CRK17036.1 - 0.09 11.9 0.0 0.45 9.6 0.0 2.0 1 1 1 2 2 2 0 PBP superfamily domain Glyco_hydro_6 PF01341.17 CRK17038.1 - 3.5e-89 299.5 6.1 4.3e-62 210.6 0.3 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 6 CBM_1 PF00734.18 CRK17038.1 - 4.8e-11 42.4 18.5 4.8e-11 42.4 18.5 2.5 2 0 0 2 2 2 1 Fungal cellulose binding domain Yeast-kill-tox PF09207.11 CRK17038.1 - 0.014 16.0 3.6 0.014 16.0 3.6 2.2 2 0 0 2 2 2 0 Yeast killer toxin Toxin_7 PF05980.12 CRK17038.1 - 3 8.2 14.5 0.56 10.5 9.5 2.4 2 0 0 2 2 2 0 Toxin 7 Adap_comp_sub PF00928.21 CRK17041.1 - 7.9e-85 284.4 0.0 9.9e-85 284.1 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CRK17041.1 - 0.00023 21.1 0.2 0.00041 20.3 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RIBIOP_C PF04950.12 CRK17041.1 - 0.072 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal Bacillus_PapR PF05968.11 CRK17043.1 - 1.6 8.7 3.7 0.67 9.9 1.0 1.8 2 0 0 2 2 2 0 Bacillus PapR protein Abhydrolase_1 PF00561.20 CRK17044.1 - 9.4e-21 74.6 0.0 1.6e-20 73.9 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CRK17044.1 - 7.5e-16 59.4 0.1 7.5e-16 59.4 0.1 1.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CRK17044.1 - 2e-10 40.4 0.0 1e-09 38.1 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 CRK17044.1 - 7e-06 24.9 0.0 1.3e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Ndr family Chlorophyllase2 PF12740.7 CRK17044.1 - 0.0044 16.0 0.0 0.0077 15.2 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme BAAT_C PF08840.11 CRK17044.1 - 0.21 11.5 0.0 9.2 6.1 0.0 2.3 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Glyco_hydro_6 PF01341.17 CRK17045.1 - 9.4e-30 104.4 0.0 1.3e-29 103.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CBM_1 PF00734.18 CRK17045.1 - 1.1e-11 44.5 18.7 1.1e-11 44.5 18.7 2.4 2 0 0 2 2 2 1 Fungal cellulose binding domain Yeast-kill-tox PF09207.11 CRK17045.1 - 0.0068 17.0 3.5 0.0068 17.0 3.5 1.8 2 0 0 2 2 2 1 Yeast killer toxin Toxin_7 PF05980.12 CRK17045.1 - 0.049 13.9 8.7 0.15 12.3 8.7 1.9 1 1 0 1 1 1 0 Toxin 7 PepSY_2 PF13670.6 CRK17045.1 - 0.76 9.8 4.9 12 5.9 0.4 2.7 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain MGC-24 PF05283.11 CRK17045.1 - 1.6 9.2 8.2 2.7 8.4 8.2 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Adap_comp_sub PF00928.21 CRK17046.1 - 7.9e-85 284.4 0.0 9.9e-85 284.1 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CRK17046.1 - 0.00023 21.1 0.2 0.00041 20.3 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RIBIOP_C PF04950.12 CRK17046.1 - 0.072 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal Bacillus_PapR PF05968.11 CRK17048.1 - 0.62 10.0 3.9 0.24 11.3 1.1 1.8 2 0 0 2 2 2 0 Bacillus PapR protein Abhydrolase_1 PF00561.20 CRK17049.1 - 1.1e-23 84.3 0.0 1.7e-23 83.6 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CRK17049.1 - 6.2e-16 59.7 0.1 1e-15 58.9 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CRK17049.1 - 2.1e-12 46.9 0.0 1e-11 44.6 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 CRK17049.1 - 4.9e-07 28.7 0.0 8.5e-07 28.0 0.0 1.3 1 0 0 1 1 1 1 Ndr family Chlorophyllase2 PF12740.7 CRK17049.1 - 0.0014 17.6 0.0 0.0031 16.4 0.0 1.4 1 1 0 1 1 1 1 Chlorophyllase enzyme PGAP1 PF07819.13 CRK17049.1 - 0.0053 16.5 0.0 0.0075 16.0 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.7 CRK17049.1 - 0.093 12.5 0.0 0.5 10.1 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family UPF0227 PF05728.12 CRK17049.1 - 0.099 12.6 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Ser_hydrolase PF06821.13 CRK17049.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase LCAT PF02450.15 CRK17049.1 - 0.19 10.9 0.0 0.3 10.2 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase BAG PF02179.16 CRK17050.1 - 2e-37 127.4 3.8 4.7e-18 65.4 0.3 2.6 2 0 0 2 2 2 2 BAG domain Ribosomal_L13 PF00572.18 CRK17050.1 - 1.4e-12 48.0 0.2 1.7e-08 34.7 0.0 3.7 2 2 0 2 2 2 2 Ribosomal protein L13 ubiquitin PF00240.23 CRK17050.1 - 7.5e-10 38.4 0.0 0.0021 17.7 0.0 2.6 2 0 0 2 2 2 2 Ubiquitin family Ubiquitin_5 PF18037.1 CRK17050.1 - 2.1e-06 28.0 0.2 0.18 12.2 0.0 3.0 3 0 0 3 3 2 2 Ubiquitin-like domain TetR_C_14 PF17754.1 CRK17050.1 - 0.0014 18.6 0.0 2.4 8.1 0.0 2.5 2 0 0 2 2 2 2 MftR C-terminal domain LIN37 PF15306.6 CRK17050.1 - 0.0034 17.6 4.4 1.5 9.0 0.0 3.4 3 1 1 4 4 4 2 LIN37 Sec61_beta PF03911.16 CRK17050.1 - 0.0048 16.9 0.5 4.7 7.3 0.1 2.6 2 0 0 2 2 2 2 Sec61beta family Ubiquitin_4 PF18036.1 CRK17050.1 - 0.0058 16.7 0.0 7.1 6.7 0.0 2.8 2 0 0 2 2 2 2 Ubiquitin-like domain GPW_gp25 PF04965.14 CRK17050.1 - 0.041 13.6 0.1 6.2 6.7 0.0 2.5 2 0 0 2 2 2 0 Gene 25-like lysozyme Antimicrobial_7 PF08102.11 CRK17050.1 - 0.043 14.0 0.4 25 5.2 0.0 3.3 4 0 0 4 4 4 0 Scorpion antimicrobial peptide AP3D1 PF06375.11 CRK17050.1 - 8.7 6.6 16.3 1.7 8.9 1.1 2.9 3 0 0 3 3 3 0 AP-3 complex subunit delta-1 Glutaredoxin PF00462.24 CRK17051.1 - 1.1e-17 64.0 0.0 1.7e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.6 CRK17051.1 - 0.00026 21.4 0.1 0.00034 21.0 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin PF00085.20 CRK17051.1 - 0.011 15.8 0.2 0.013 15.4 0.2 1.4 1 1 0 1 1 1 0 Thioredoxin DSBA PF01323.20 CRK17051.1 - 0.011 15.5 0.0 0.025 14.4 0.0 1.8 1 1 0 1 1 1 0 DSBA-like thioredoxin domain DUF836 PF05768.14 CRK17051.1 - 0.013 15.9 0.0 0.02 15.3 0.0 1.5 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) TraF PF13728.6 CRK17051.1 - 0.06 13.2 0.0 0.08 12.7 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein Chalcone_2 PF16035.5 CRK17052.1 - 6e-60 202.5 0.0 7.1e-60 202.3 0.0 1.0 1 0 0 1 1 1 1 Chalcone isomerase like Glutaredoxin PF00462.24 CRK17053.1 - 1.2e-16 60.6 0.0 1.9e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin PF00085.20 CRK17053.1 - 0.0016 18.4 0.1 0.0019 18.1 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 CRK17053.1 - 0.011 16.2 0.1 0.017 15.6 0.1 1.4 1 1 0 1 1 1 0 Thioredoxin-like domain DSBA PF01323.20 CRK17053.1 - 0.016 15.0 0.0 0.036 13.8 0.0 1.8 1 1 0 1 1 1 0 DSBA-like thioredoxin domain DUF836 PF05768.14 CRK17053.1 - 0.016 15.6 0.0 0.024 15.1 0.0 1.4 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin_4 PF13462.6 CRK17053.1 - 0.052 13.7 0.3 0.17 12.0 0.2 2.0 1 1 1 2 2 2 0 Thioredoxin Thioredoxin_9 PF14595.6 CRK17053.1 - 0.092 12.5 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin LRR_6 PF13516.6 CRK17054.1 - 4e-18 63.8 14.8 0.53 10.5 0.1 12.1 13 0 0 13 13 13 6 Leucine Rich repeat LRR_4 PF12799.7 CRK17054.1 - 5e-13 49.0 11.5 0.43 11.1 0.0 7.4 5 2 1 7 7 7 5 Leucine Rich repeats (2 copies) F-box-like PF12937.7 CRK17054.1 - 8.1e-11 41.6 1.7 1.7e-10 40.6 0.3 2.4 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 CRK17054.1 - 2.8e-05 23.9 0.7 0.00012 21.8 0.0 2.4 2 0 0 2 2 2 1 F-box domain LRR_8 PF13855.6 CRK17054.1 - 0.011 15.4 4.7 1.1 9.1 0.0 5.0 5 2 1 6 6 6 0 Leucine rich repeat WAK_assoc PF14380.6 CRK17055.1 - 0.061 14.1 1.0 0.11 13.3 1.0 1.4 1 0 0 1 1 1 0 Wall-associated receptor kinase C-terminal LRR_6 PF13516.6 CRK17056.1 - 8.8e-20 69.0 14.4 0.39 10.9 0.1 12.3 13 0 0 13 13 13 7 Leucine Rich repeat LRR_4 PF12799.7 CRK17056.1 - 3.8e-14 52.6 11.1 0.29 11.6 0.0 7.6 5 2 2 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CRK17056.1 - 0.0012 18.5 3.7 0.79 9.5 0.0 5.5 5 2 1 6 6 6 2 Leucine rich repeat Pertussis_S1 PF02917.14 CRK17058.1 - 0.077 12.8 0.2 0.11 12.3 0.2 1.3 1 1 0 1 1 1 0 Pertussis toxin, subunit 1 AIRS PF00586.24 CRK17059.1 - 0.075 13.7 0.0 0.097 13.3 0.0 1.3 1 0 0 1 1 1 0 AIR synthase related protein, N-terminal domain Glyco_hydro_61 PF03443.14 CRK17062.1 - 7.2e-51 173.0 0.0 9.8e-51 172.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 SoPB_HTH PF18090.1 CRK17067.1 - 0.07 13.3 0.3 0.14 12.3 0.3 1.5 1 0 0 1 1 1 0 Centromere-binding protein HTH domain YopE PF03545.13 CRK17068.1 - 0.13 12.4 0.1 0.28 11.4 0.1 1.5 1 0 0 1 1 1 0 Yersinia virulence determinant (YopE) Cpn60_TCP1 PF00118.24 CRK17069.1 - 8e-80 268.8 0.1 9.9e-80 268.5 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family F_bP_aldolase PF01116.20 CRK17070.1 - 4.7e-49 167.4 0.0 5.7e-49 167.1 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Pec_lyase_C PF00544.19 CRK17084.1 - 1.1e-11 44.7 11.3 3.2e-10 40.0 8.6 2.9 2 1 0 2 2 2 1 Pectate lyase Beta_helix PF13229.6 CRK17084.1 - 2.2e-06 27.6 13.5 0.0019 18.0 1.7 2.4 1 1 1 2 2 2 2 Right handed beta helix region FMN_dh PF01070.18 CRK17084.1 - 2.5e-06 26.8 0.0 3.5e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Phage_attach PF05354.11 CRK17084.1 - 0.053 13.4 0.1 0.37 10.7 0.1 2.1 2 0 0 2 2 2 0 Phage Head-Tail Attachment TRP PF06011.12 CRK17111.1 - 4.6e-108 361.7 17.3 5.3e-108 361.5 17.3 1.0 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 CRK17111.1 - 2.3e-13 50.7 0.1 5.4e-13 49.5 0.0 1.6 2 0 0 2 2 2 1 ML-like domain PhzC-PhzF PF02567.16 CRK17111.1 - 3e-11 43.3 0.0 4.5e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein TFIIA PF03153.13 CRK17112.1 - 0.75 9.7 23.0 0.68 9.9 12.7 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit zf-C2H2 PF00096.26 CRK17112.1 - 2.2 8.9 12.5 0.58 10.7 1.6 3.2 3 0 0 3 3 3 0 Zinc finger, C2H2 type GalKase_gal_bdg PF10509.9 CRK17114.1 - 4.3e-21 74.2 0.1 7.4e-21 73.4 0.1 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 CRK17114.1 - 4.1e-13 49.4 3.1 1.5e-12 47.6 3.1 2.0 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 CRK17114.1 - 1.2e-12 48.0 0.0 7.1e-12 45.5 0.0 2.2 2 0 0 2 2 2 1 GHMP kinases C terminal Cu-oxidase_2 PF07731.14 CRK17115.1 - 1.6e-38 131.5 0.5 4.3e-38 130.1 0.2 1.9 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 CRK17115.1 - 3.9e-32 111.6 1.1 3.9e-32 111.6 1.1 2.5 3 0 0 3 3 3 1 Multicopper oxidase Peptidase_S28 PF05577.12 CRK17117.1 - 3.9e-50 170.9 0.0 1.8e-49 168.7 0.0 1.8 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Glyco_hydro_43 PF04616.14 CRK17118.1 - 2.7e-12 46.6 0.1 3.1e-12 46.4 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Tudor_2 PF18104.1 CRK17118.1 - 0.026 14.2 0.3 0.058 13.1 0.3 1.5 1 0 0 1 1 1 0 Jumonji domain-containing protein 2A Tudor domain BRCA-2_OB1 PF09103.10 CRK17118.1 - 0.17 11.8 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 Glyco_hydro_43 PF04616.14 CRK17119.1 - 9.5e-37 126.9 0.3 1.1e-36 126.6 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 AbfB PF05270.13 CRK17119.1 - 9.3e-11 41.9 0.0 5.1e-06 26.5 0.0 2.7 1 1 1 2 2 2 2 Alpha-L-arabinofuranosidase B (ABFB) domain Sulfotransfer_4 PF17784.1 CRK17121.1 - 1.4e-57 194.9 0.0 1.7e-57 194.7 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CRK17121.1 - 0.0098 16.3 0.1 0.055 13.8 0.0 2.2 1 1 1 2 2 2 1 Sulfotransferase family Pectate_lyase PF03211.13 CRK17122.1 - 2.7e-63 213.2 1.7 3.4e-63 212.9 1.7 1.1 1 0 0 1 1 1 1 Pectate lyase FMO-like PF00743.19 CRK17124.1 - 4.9e-34 117.6 0.0 2.9e-16 59.0 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 CRK17124.1 - 9.9e-23 80.8 1.0 1.2e-16 60.9 0.1 2.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CRK17124.1 - 5.4e-13 48.8 0.7 4.5e-08 32.6 0.0 3.0 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 CRK17124.1 - 1.9e-12 47.1 0.0 3e-06 26.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CRK17124.1 - 1.6e-09 37.8 0.1 8.3e-06 25.6 0.0 2.8 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CRK17124.1 - 4.4e-08 33.2 0.0 1.1e-07 32.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 CRK17124.1 - 5.4e-08 33.0 2.4 7.3e-07 29.3 0.6 3.5 3 1 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 CRK17124.1 - 8.2e-06 26.3 0.5 0.00053 20.5 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CRK17124.1 - 0.00011 21.6 0.1 0.00033 20.0 0.0 1.8 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 CRK17124.1 - 0.00011 21.1 0.2 0.0002 20.2 0.2 1.4 1 0 0 1 1 1 1 HI0933-like protein Amino_oxidase PF01593.24 CRK17124.1 - 0.00053 19.4 0.0 0.0057 16.0 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Shikimate_DH PF01488.20 CRK17124.1 - 0.0021 18.1 0.0 0.007 16.4 0.0 1.8 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 CRK17124.1 - 0.006 15.7 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 CRK17124.1 - 0.0071 15.7 2.4 0.0072 15.7 0.7 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 CRK17124.1 - 0.0084 15.4 0.2 0.021 14.1 0.1 1.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 CRK17124.1 - 0.05 12.7 0.2 0.092 11.8 0.2 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Glu_dehyd_C PF16912.5 CRK17124.1 - 0.072 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus NAD_binding_2 PF03446.15 CRK17124.1 - 0.14 12.3 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase CUE PF02845.16 CRK17125.1 - 2.8e-05 23.7 0.0 4.8e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 CUE domain DUF3697 PF12478.8 CRK17125.1 - 0.0024 17.9 0.0 0.0063 16.6 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-associated protein 2 2OG-FeII_Oxy PF03171.20 CRK17127.1 - 3.9e-16 59.4 0.1 8e-16 58.4 0.1 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 CRK17127.1 - 6.3e-13 49.5 0.1 1.2e-12 48.6 0.1 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal DEAD PF00270.29 CRK17129.1 - 4.1e-50 170.0 0.0 6.1e-50 169.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CRK17129.1 - 1.1e-32 112.7 0.1 8.8e-32 109.8 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CRK17129.1 - 5.9e-05 23.1 0.0 0.0001 22.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CRK17129.1 - 0.11 12.7 0.0 0.37 11.0 0.0 1.9 2 1 0 2 2 2 0 AAA domain Brix PF04427.18 CRK17130.1 - 4.4e-48 164.0 0.0 5.5e-48 163.6 0.0 1.1 1 0 0 1 1 1 1 Brix domain PPP4R2 PF09184.11 CRK17130.1 - 9.3 5.7 15.3 17 4.9 15.3 1.4 1 0 0 1 1 1 0 PPP4R2 PI3K_1B_p101 PF10486.9 CRK17131.1 - 3.5 5.3 5.2 7.1 4.3 5.2 1.4 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit FAD_binding_3 PF01494.19 CRK17132.1 - 4.6e-15 55.7 0.8 3.1e-08 33.3 0.4 2.9 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 CRK17132.1 - 0.00058 20.0 0.1 0.0014 18.8 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CRK17132.1 - 0.0022 17.7 0.1 0.0056 16.3 0.1 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 CRK17132.1 - 0.0043 17.1 0.1 0.02 14.9 0.1 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 CRK17132.1 - 0.045 12.8 0.3 0.17 10.9 0.3 1.8 1 1 0 1 1 1 0 Lycopene cyclase protein Shikimate_DH PF01488.20 CRK17132.1 - 0.046 13.8 0.0 0.099 12.7 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.14 CRK17132.1 - 0.21 10.8 0.0 4 6.6 0.0 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 CRK17134.1 - 3.8e-33 114.9 35.2 7e-33 114.0 35.2 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 CRK17134.1 - 0.0065 15.4 14.8 0.0085 15.0 13.4 1.7 1 1 0 1 1 1 1 MFS_1 like family Zn_clus PF00172.18 CRK17135.1 - 8.8e-08 32.1 10.2 8.8e-08 32.1 10.2 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 CRK17135.1 - 2.1e-06 26.8 0.1 5.7e-06 25.4 0.1 1.6 1 1 1 2 2 2 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 CRK17136.1 - 1.9e-08 33.7 0.6 3.9e-08 32.7 0.6 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK17136.1 - 0.0013 18.8 8.5 0.0022 18.0 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IFP_35_N PF07334.13 CRK17136.1 - 0.15 12.2 0.3 0.77 9.9 0.0 2.3 3 0 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Isochorismatase PF00857.20 CRK17137.1 - 1.1e-20 74.5 0.0 1.5e-20 74.1 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family Glyco_hydro_15 PF00723.21 CRK17138.1 - 2.3e-99 333.2 0.0 2.8e-99 332.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.19 CRK17138.1 - 5.4e-35 119.2 0.6 1.2e-34 118.1 0.6 1.6 1 0 0 1 1 1 1 Starch binding domain BTB PF00651.31 CRK17139.1 - 0.0013 19.0 0.0 0.0031 17.7 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain Glyco_hydro_67M PF07488.12 CRK17140.1 - 9.8e-145 481.6 0.0 1.3e-144 481.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67C PF07477.12 CRK17140.1 - 3.6e-90 301.4 2.1 5.5e-90 300.8 2.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 C-terminus Glyco_hydro_67N PF03648.14 CRK17140.1 - 3.1e-27 95.3 0.0 6e-27 94.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus Glyco_hydro_20b PF02838.15 CRK17140.1 - 0.0043 17.8 0.2 0.014 16.2 0.1 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 Asn_synthase PF00733.21 CRK17141.1 - 2.4e-18 66.9 2.4 7.8e-08 32.4 0.3 3.1 2 1 1 3 3 3 3 Asparagine synthase GATase_7 PF13537.6 CRK17141.1 - 2.3e-06 27.6 0.0 7.4e-06 25.9 0.0 1.9 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 CRK17141.1 - 0.0022 18.2 0.0 0.0053 17.0 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain Poxvirus_B22R PF04395.12 CRK17141.1 - 0.0071 15.9 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Poxvirus B22R protein DUF3700 PF12481.8 CRK17141.1 - 0.12 11.8 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Aluminium induced protein PHD PF00628.29 CRK17142.1 - 2.2e-05 24.3 7.7 3.3e-05 23.7 7.7 1.3 1 0 0 1 1 1 1 PHD-finger zf-PHD-like PF15446.6 CRK17142.1 - 0.011 15.4 1.0 0.079 12.6 0.4 2.1 1 1 1 2 2 2 0 PHD/FYVE-zinc-finger like domain Prok-RING_1 PF14446.6 CRK17142.1 - 0.023 14.6 3.3 0.047 13.6 3.3 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 C1_2 PF03107.16 CRK17142.1 - 0.12 12.8 1.7 0.26 11.6 0.4 2.0 2 0 0 2 2 2 0 C1 domain C1_1 PF00130.22 CRK17142.1 - 0.15 12.0 4.2 0.069 13.1 1.1 1.9 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.6 CRK17142.1 - 7.7 6.2 9.7 1 8.9 4.3 2.2 2 0 0 2 2 2 0 PHD-finger NAD_binding_10 PF13460.6 CRK17143.1 - 5.2e-07 29.7 0.0 6.6e-06 26.1 0.0 2.2 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 CRK17143.1 - 0.00066 19.3 0.0 0.0013 18.3 0.0 1.5 2 0 0 2 2 2 1 NmrA-like family GDP_Man_Dehyd PF16363.5 CRK17143.1 - 0.044 13.2 0.0 0.064 12.6 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase FAD_binding_4 PF01565.23 CRK17144.1 - 1.8e-07 31.0 0.2 1e-06 28.5 0.2 2.2 1 1 0 1 1 1 1 FAD binding domain CRC_subunit PF08624.10 CRK17145.1 - 2.8e-52 176.7 0.0 4.3e-52 176.1 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit CDC45 PF02724.14 CRK17145.1 - 1.3 7.2 4.4 1.8 6.7 4.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 CRK17145.1 - 3.9 5.6 7.3 5.4 5.1 7.3 1.1 1 0 0 1 1 1 0 Nop14-like family Cyclin PF08613.11 CRK17146.1 - 5.1e-09 36.7 0.0 8.7e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 CRK17146.1 - 2.2e-05 24.2 0.0 3.7e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Tubulin_C PF03953.17 CRK17148.1 - 2.8e-36 124.5 0.0 4.3e-36 123.9 0.0 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.25 CRK17148.1 - 1.3e-24 87.5 0.0 2.4e-24 86.7 0.0 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain zf-CCHC PF00098.23 CRK17149.1 - 1.3e-29 100.9 38.0 8.3e-08 32.0 2.4 5.2 5 0 0 5 5 5 5 Zinc knuckle zf-CCHC_5 PF14787.6 CRK17149.1 - 8.8e-05 22.1 26.2 0.0033 17.1 1.0 4.4 3 1 1 4 4 4 3 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.6 CRK17149.1 - 0.00057 19.6 27.0 0.21 11.3 0.7 4.7 5 0 0 5 5 5 4 Zinc knuckle zf-CCHC_2 PF13696.6 CRK17149.1 - 0.004 16.9 1.9 0.004 16.9 1.9 4.5 4 0 0 4 4 4 1 Zinc knuckle zf-CCHC_3 PF13917.6 CRK17149.1 - 0.048 13.6 0.1 0.048 13.6 0.1 4.4 3 1 1 4 4 4 0 Zinc knuckle Pkinase PF00069.25 CRK17153.1 - 7.1e-11 42.0 0.0 7.7e-11 41.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK17153.1 - 4.7e-08 32.6 0.0 5.1e-08 32.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2101 PF09874.9 CRK17153.1 - 0.031 14.0 0.1 0.035 13.8 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2101) Iso_dh PF00180.20 CRK17155.1 - 5.3e-29 101.4 0.0 5.8e-29 101.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Phage_30_3 PF08010.11 CRK17155.1 - 0.0098 15.7 0.0 0.014 15.2 0.0 1.2 1 0 0 1 1 1 1 Bacteriophage protein GP30.3 eIF3g PF12353.8 CRK17157.1 - 1.7e-43 148.0 4.7 2.1e-43 147.7 4.7 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G zf-CCCH_7 PF18586.1 CRK17157.1 - 0.013 15.8 0.2 0.029 14.7 0.2 1.5 1 0 0 1 1 1 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 Ribosomal_S7 PF00177.21 CRK17158.1 - 1.1e-25 90.0 0.9 1.2e-25 89.9 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Nop25 PF09805.9 CRK17164.1 - 2.5e-39 134.9 19.0 2.5e-39 134.9 19.0 2.0 2 0 0 2 2 2 1 Nucleolar protein 12 (25kDa) HrpE PF06188.12 CRK17164.1 - 0.07 13.0 2.4 0.094 12.6 2.4 1.1 1 0 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E Lipl32 PF12103.8 CRK17164.1 - 0.56 9.8 11.1 0.12 12.0 3.6 2.0 1 1 1 2 2 2 0 Surface lipoprotein of Spirochaetales order GWT1 PF06423.12 CRK17180.1 - 9.9e-27 93.9 0.1 1.7e-26 93.1 0.1 1.4 1 0 0 1 1 1 1 GWT1 DUF4714 PF15833.5 CRK17180.1 - 0.05 13.6 0.2 5.2 7.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4714) OB_NTP_bind PF07717.16 CRK17212.1 - 4.3e-10 39.8 0.2 1.2e-09 38.4 0.1 1.8 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold V-SNARE_C PF12352.8 CRK17212.1 - 0.05 13.9 1.5 0.13 12.6 1.5 1.6 1 0 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus CorA PF01544.18 CRK17212.1 - 1.6 8.0 4.7 2.6 7.3 4.7 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein FPN1 PF06963.12 CRK17214.1 - 3.1e-113 378.6 15.7 4.1e-113 378.2 15.7 1.1 1 0 0 1 1 1 1 Ferroportin1 (FPN1) Alpha-amylase PF00128.24 CRK17214.1 - 1.1e-107 360.5 0.0 1.8e-107 359.8 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain GTP_EFTU PF00009.27 CRK17214.1 - 1.2e-08 34.8 0.0 3.1e-08 33.4 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Malt_amylase_C PF16657.5 CRK17214.1 - 3.7e-05 23.7 0.0 0.00011 22.3 0.0 1.8 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain AAA_29 PF13555.6 CRK17214.1 - 0.21 11.4 0.9 0.48 10.2 0.9 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rab5ip PF07019.12 CRK17217.1 - 1.2e-27 96.2 6.5 1.5e-27 96.0 6.5 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) PspC PF04024.12 CRK17217.1 - 0.38 10.6 2.3 9.9 6.1 0.0 2.8 2 1 0 2 2 2 0 PspC domain COesterase PF00135.28 CRK17220.1 - 3.3e-71 240.7 0.0 3.7e-66 224.1 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 CRK17220.1 - 1.1e-07 32.0 0.5 6.1e-07 29.5 0.5 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF4191 PF13829.6 CRK17221.1 - 1.8 7.9 4.2 3.3 7.0 4.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4191) HET PF06985.11 CRK17223.1 - 0.00084 19.7 0.4 0.014 15.7 0.9 2.8 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Tube PF17212.3 CRK17223.1 - 0.11 12.5 0.0 0.4 10.7 0.0 1.8 2 0 0 2 2 2 0 Tail tubular protein Fungal_trans PF04082.18 CRK17225.1 - 4.5e-15 55.4 0.0 5.7e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain AJAP1_PANP_C PF15298.6 CRK17228.1 - 0.0021 18.3 1.6 0.003 17.8 1.6 1.2 1 0 0 1 1 1 1 AJAP1/PANP C-terminus TMEM51 PF15345.6 CRK17228.1 - 0.0025 17.7 0.1 0.0039 17.1 0.1 1.2 1 0 0 1 1 1 1 Transmembrane protein 51 Mid2 PF04478.12 CRK17228.1 - 0.15 11.9 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor TMEM108 PF15759.5 CRK17228.1 - 1.7 7.6 12.3 3.3 6.6 6.4 2.2 1 1 1 2 2 2 0 TMEM108 family DUF2235 PF09994.9 CRK17229.1 - 2.6e-60 204.3 0.0 3.2e-60 203.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_1 PF00561.20 CRK17229.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Glyco_trans_4_4 PF13579.6 CRK17231.1 - 1.8e-11 44.7 0.1 2.6e-11 44.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 CRK17231.1 - 1.1e-05 25.5 0.0 1.5e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase Family 4 ABC_tran PF00005.27 CRK17233.1 - 4.7e-25 88.7 0.0 8.5e-25 87.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CRK17233.1 - 1.7e-05 24.8 0.2 0.16 11.7 0.0 2.4 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 CRK17233.1 - 2.8e-05 24.6 0.0 4.3e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 CRK17233.1 - 6.6e-05 22.6 0.1 0.00011 21.8 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CRK17233.1 - 0.00028 21.2 0.0 0.00075 19.8 0.0 1.8 2 0 0 2 2 1 1 AAA domain RsgA_GTPase PF03193.16 CRK17233.1 - 0.00029 20.8 0.1 0.0012 18.8 0.1 1.9 2 0 0 2 2 2 1 RsgA GTPase SMC_N PF02463.19 CRK17233.1 - 0.00084 18.8 0.0 0.014 14.8 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain T2SSE PF00437.20 CRK17233.1 - 0.0017 17.5 0.1 0.0028 16.8 0.1 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.6 CRK17233.1 - 0.0035 17.0 0.1 0.0068 16.1 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain NTPase_1 PF03266.15 CRK17233.1 - 0.0044 16.9 0.5 0.016 15.2 0.2 2.1 2 1 0 2 2 2 1 NTPase NACHT PF05729.12 CRK17233.1 - 0.0046 16.9 0.1 0.0087 16.0 0.1 1.4 1 0 0 1 1 1 1 NACHT domain cobW PF02492.19 CRK17233.1 - 0.0089 15.6 0.1 0.013 15.0 0.1 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 CRK17233.1 - 0.011 15.5 0.3 0.02 14.7 0.1 1.6 2 0 0 2 2 1 0 AAA domain AAA_30 PF13604.6 CRK17233.1 - 0.014 15.2 0.9 0.028 14.1 0.8 1.5 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 CRK17233.1 - 0.014 15.7 0.3 0.025 14.8 0.3 1.4 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 CRK17233.1 - 0.015 15.4 0.2 0.029 14.4 0.2 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_14 PF13173.6 CRK17233.1 - 0.015 15.3 0.1 0.27 11.3 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 CRK17233.1 - 0.016 15.4 0.0 0.067 13.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 CRK17233.1 - 0.023 14.4 0.0 0.045 13.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 CRK17233.1 - 0.026 14.9 0.0 0.056 13.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase MobB PF03205.14 CRK17233.1 - 0.028 14.3 0.1 0.053 13.4 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.29 CRK17233.1 - 0.035 14.5 0.1 0.4 11.1 0.1 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 CRK17233.1 - 0.038 14.5 0.1 0.076 13.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 CRK17233.1 - 0.039 14.3 0.2 0.11 12.9 0.2 1.8 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 CRK17233.1 - 0.053 13.1 0.1 0.096 12.3 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_23 PF13476.6 CRK17233.1 - 0.065 13.7 0.2 0.13 12.7 0.2 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 CRK17233.1 - 0.095 12.7 0.0 0.29 11.1 0.1 1.8 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) Cytidylate_kin PF02224.18 CRK17233.1 - 0.13 11.9 0.2 0.23 11.2 0.2 1.3 1 0 0 1 1 1 0 Cytidylate kinase Septin PF00735.18 CRK17233.1 - 0.14 11.4 0.1 0.24 10.6 0.1 1.3 1 0 0 1 1 1 0 Septin ATP_bind_1 PF03029.17 CRK17233.1 - 0.15 11.8 0.2 0.27 11.0 0.2 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Rad17 PF03215.15 CRK17233.1 - 0.15 11.9 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain FtsK_SpoIIIE PF01580.18 CRK17233.1 - 0.15 11.3 0.1 0.28 10.5 0.1 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family ATPase_2 PF01637.18 CRK17233.1 - 0.16 11.9 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 CRK17233.1 - 0.16 11.1 1.5 0.66 9.1 0.1 2.1 1 1 1 2 2 2 0 NB-ARC domain AAA_35 PF14516.6 CRK17233.1 - 0.21 10.4 0.0 0.32 9.8 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain Zn_clus PF00172.18 CRK17235.1 - 7.7e-09 35.5 9.0 1.5e-08 34.6 9.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GFO_IDH_MocA PF01408.22 CRK17237.1 - 1e-20 74.7 0.2 1.7e-20 74.1 0.2 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 CRK17237.1 - 1.2e-06 29.1 0.2 2.2e-06 28.3 0.2 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 CRK17237.1 - 0.0015 19.0 0.0 0.0081 16.6 0.0 2.0 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DUF5006 PF16397.5 CRK17237.1 - 0.038 13.2 0.0 0.061 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5006) Glyco_hydro_7 PF00840.20 CRK17239.1 - 4.5e-152 506.8 2.9 5.1e-152 506.6 2.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Pkinase PF00069.25 CRK17246.1 - 2.8e-14 53.1 0.0 4.3e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK17246.1 - 0.0011 18.3 0.0 0.0019 17.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase EMC3_TMCO1 PF01956.16 CRK17248.1 - 0.042 13.6 1.0 0.07 12.9 1.0 1.3 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like NAD_binding_8 PF13450.6 CRK17250.1 - 1.7e-10 41.0 0.1 4e-10 39.8 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 CRK17250.1 - 1.4e-05 24.7 0.7 2.2e-05 24.0 0.2 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 CRK17250.1 - 1.8e-05 24.2 0.1 0.00069 19.0 0.1 2.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 CRK17250.1 - 7.2e-05 22.0 2.8 0.00012 21.4 2.8 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 CRK17250.1 - 0.00016 20.5 0.5 0.00025 19.9 0.5 1.3 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 CRK17250.1 - 0.00052 19.3 0.4 0.00088 18.6 0.4 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 CRK17250.1 - 0.00058 20.4 0.5 0.0028 18.2 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CRK17250.1 - 0.0015 18.2 1.3 0.0034 17.0 1.3 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CRK17250.1 - 0.004 16.4 0.1 0.007 15.6 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CRK17250.1 - 0.031 13.5 0.0 0.06 12.6 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CRK17250.1 - 0.14 11.1 0.1 0.23 10.4 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 CRK17250.1 - 0.22 10.7 1.0 0.35 10.1 0.4 1.6 2 0 0 2 2 2 0 FAD binding domain Peptidase_M43 PF05572.13 CRK17252.1 - 3.9e-12 46.3 0.1 8.1e-12 45.3 0.1 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 CRK17252.1 - 3.9e-08 33.9 0.0 7.5e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 CRK17252.1 - 1.1e-06 29.0 0.0 2.3e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 CRK17252.1 - 0.0012 18.6 0.0 0.0022 17.7 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 CRK17252.1 - 0.0033 17.3 0.0 0.0055 16.6 0.0 1.3 1 0 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease DUF4953 PF16313.5 CRK17252.1 - 0.014 14.7 0.1 0.055 12.7 0.0 1.8 2 0 0 2 2 2 0 Met-zincin Peptidase_M10 PF00413.24 CRK17252.1 - 0.014 15.3 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 Matrixin Peptidase_M66 PF10462.9 CRK17252.1 - 0.097 11.6 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Peptidase M66 Sugar_tr PF00083.24 CRK17254.1 - 1.2e-84 284.9 24.9 1.3e-84 284.6 24.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK17254.1 - 5.2e-48 163.8 46.4 9.3e-38 130.0 25.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CRK17254.1 - 0.0016 16.9 3.3 0.0016 16.9 3.3 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Scm3 PF10384.9 CRK17254.1 - 0.038 13.7 0.0 0.067 12.9 0.0 1.3 1 0 0 1 1 1 0 Centromere protein Scm3 Cupin_1 PF00190.22 CRK17259.1 - 0.0054 16.4 0.8 0.012 15.2 0.8 1.6 1 1 0 1 1 1 1 Cupin Cupin_2 PF07883.11 CRK17259.1 - 0.013 15.2 0.7 0.063 13.0 0.0 2.2 1 1 1 2 2 2 0 Cupin domain CENP-L PF13092.6 CRK17260.1 - 8.2e-53 179.0 0.0 1.3e-52 178.3 0.0 1.3 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 NAD_binding_7 PF13241.6 CRK17262.1 - 2.5e-30 105.0 0.0 8.7e-30 103.2 0.0 2.0 2 0 0 2 2 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 CRK17262.1 - 2.6e-26 91.0 0.0 1e-25 89.1 0.0 2.1 2 0 0 2 2 2 1 Sirohaem biosynthesis protein C-terminal Rbsn PF11464.8 CRK17262.1 - 4.2e-17 61.6 1.4 4.2e-17 61.6 1.4 1.9 2 0 0 2 2 2 1 Rabenosyn Rab binding domain Sirohm_synth_M PF14824.6 CRK17262.1 - 8.5e-15 53.9 0.3 8.5e-15 53.9 0.3 2.2 2 0 0 2 2 2 1 Sirohaem biosynthesis protein central FYVE PF01363.21 CRK17262.1 - 8.2e-07 29.1 11.5 2.5e-06 27.6 7.3 3.0 3 0 0 3 3 3 1 FYVE zinc finger zf-AN1 PF01428.16 CRK17262.1 - 0.0021 18.2 2.7 0.0021 18.2 2.7 1.9 2 0 0 2 2 1 1 AN1-like Zinc finger Pyr_redox_3 PF13738.6 CRK17262.1 - 0.026 13.8 0.1 0.055 12.7 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase zf-Di19 PF05605.12 CRK17262.1 - 0.04 14.2 0.1 0.14 12.5 0.1 1.9 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-NADH-PPase PF09297.11 CRK17262.1 - 0.24 11.1 5.7 0.63 9.7 0.2 3.1 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain bZIP_1 PF00170.21 CRK17262.1 - 4 7.6 5.8 13 5.9 0.0 3.3 3 0 0 3 3 3 0 bZIP transcription factor TMF_TATA_bd PF12325.8 CRK17262.1 - 5.3 7.3 11.5 0.2 11.9 2.9 2.9 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Ank_2 PF12796.7 CRK17265.1 - 4.1e-13 49.7 0.2 7.7e-05 23.2 0.1 3.6 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CRK17265.1 - 5.4e-13 49.2 4.7 1.5e-07 31.8 0.2 4.3 3 2 3 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CRK17265.1 - 2.7e-09 36.5 0.8 0.01 16.3 0.0 4.9 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 CRK17265.1 - 1.9e-08 34.4 4.4 0.076 13.5 0.1 4.8 5 0 0 5 5 5 2 Ankyrin repeat KilA-N PF04383.13 CRK17265.1 - 1.4e-05 24.9 0.9 0.0001 22.1 0.3 2.5 2 1 0 2 2 2 1 KilA-N domain Ank_5 PF13857.6 CRK17265.1 - 6.6e-05 23.1 0.4 0.92 9.9 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Med2 PF11214.8 CRK17265.1 - 0.054 13.7 4.2 0.12 12.6 4.2 1.6 1 0 0 1 1 1 0 Mediator complex subunit 2 HrpB1_HrpK PF09613.10 CRK17265.1 - 0.056 13.1 0.7 0.15 11.7 0.7 1.6 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) Muted PF14942.6 CRK17265.1 - 0.79 10.1 7.3 1.8 8.9 7.3 1.6 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Complex1_LYR PF05347.15 CRK17267.1 - 4.8e-05 23.3 0.2 0.0002 21.3 0.2 2.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 CRK17267.1 - 0.62 10.9 7.7 1.5 9.6 6.1 2.6 2 1 0 2 2 2 0 Complex1_LYR-like FUSC PF04632.12 CRK17267.1 - 6.4 5.2 6.6 9.4 4.6 6.6 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Acetyltransf_1 PF00583.25 CRK17269.1 - 2.7e-16 59.9 0.0 6e-16 58.7 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 CRK17269.1 - 1.8e-08 34.2 0.1 4.7e-08 32.9 0.0 1.7 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_7 PF13508.7 CRK17269.1 - 2.1e-07 31.2 0.0 3.3e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 CRK17269.1 - 1.8e-06 28.2 0.0 8.5e-05 22.7 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 CRK17269.1 - 9.5e-06 26.3 0.0 1.3e-05 25.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CRK17269.1 - 1.4e-05 25.0 0.0 2.2e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CRK17269.1 - 0.036 14.2 0.0 0.058 13.5 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF4349 PF14257.6 CRK17269.1 - 0.07 12.6 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) PanZ PF12568.8 CRK17269.1 - 0.11 12.2 0.1 0.22 11.3 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Plant_NMP1 PF06694.11 CRK17269.1 - 0.2 10.7 0.0 0.32 10.0 0.0 1.2 1 0 0 1 1 1 0 Plant nuclear matrix protein 1 (NMP1) Transferase PF02458.15 CRK17271.1 - 1.1e-11 44.1 0.0 1.2e-07 30.8 0.0 3.2 3 0 0 3 3 3 3 Transferase family Con-6 PF10346.9 CRK17272.1 - 5.2e-17 61.6 1.9 1.3e-16 60.3 1.4 1.8 2 0 0 2 2 2 1 Conidiation protein 6 Fungal_trans PF04082.18 CRK17275.1 - 2.4e-12 46.5 0.1 3.2e-12 46.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_2_C PF02836.17 CRK17293.1 - 4.9e-51 173.6 0.3 5.7e-51 173.4 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.15 CRK17293.1 - 0.024 14.0 0.0 0.028 13.8 0.0 1.1 1 0 0 1 1 1 0 Beta-galactosidase Glyco_hydro_38N PF01074.22 CRK17300.1 - 1.1e-84 284.3 2.1 1.4e-84 283.9 2.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain DUF1348 PF07080.11 CRK17300.1 - 0.076 12.9 1.7 0.15 12.0 0.3 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1348) HopA1 PF17914.1 CRK17300.1 - 0.1 12.3 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 HopA1 effector protein family Glyco_hydro_1 PF00232.18 CRK17301.1 - 1.5e-117 392.8 0.0 1.9e-117 392.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 TPR_2 PF07719.17 CRK17313.1 - 0.11 12.7 9.4 3.7 7.9 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3110 PF11360.8 CRK17313.1 - 0.32 11.2 3.6 0.55 10.5 0.9 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3110) Kinesin PF00225.23 CRK17331.1 - 3.6e-31 108.3 0.3 4.4e-31 108.0 0.3 1.0 1 0 0 1 1 1 1 Kinesin motor domain Enolase_C PF00113.22 CRK17336.1 - 6.1e-63 212.8 0.3 7.4e-63 212.5 0.3 1.0 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain MAAL_C PF07476.11 CRK17336.1 - 0.0038 16.4 0.1 0.0052 16.0 0.1 1.1 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus LRR_6 PF13516.6 CRK17337.1 - 1.3e-07 31.1 1.4 0.029 14.4 0.0 4.8 6 0 0 6 6 6 2 Leucine Rich repeat LRR_4 PF12799.7 CRK17337.1 - 1.6e-05 25.2 0.6 0.25 11.8 0.0 4.2 5 0 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CRK17337.1 - 0.00046 19.9 3.6 0.53 10.1 0.1 4.0 3 1 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.33 CRK17337.1 - 0.0015 18.8 0.0 78 4.4 0.0 4.5 4 0 0 4 4 4 0 Leucine Rich Repeat RNA_pol_Rpb6 PF01192.22 CRK17337.1 - 0.035 14.0 1.3 0.3 11.1 0.1 2.4 2 0 0 2 2 2 0 RNA polymerase Rpb6 Kinesin PF00225.23 CRK17341.1 - 2e-40 138.7 0.0 3.9e-22 78.6 0.0 2.5 2 1 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 CRK17341.1 - 4.8e-10 39.6 0.0 6.3e-07 29.4 0.0 2.5 2 0 0 2 2 2 2 Microtubule binding EzrA PF06160.12 CRK17341.1 - 0.046 11.9 1.4 0.068 11.3 1.4 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Jnk-SapK_ap_N PF09744.9 CRK17341.1 - 3.1 8.0 9.1 0.54 10.5 4.1 1.9 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Peptidase_M57 PF12388.8 CRK17342.1 - 0.024 14.3 0.2 1.4 8.5 0.0 2.1 1 1 1 2 2 2 0 Dual-action HEIGH metallo-peptidase SNF PF00209.18 CRK17343.1 - 3.7e-89 299.8 38.8 4.9e-55 187.2 18.0 2.3 2 1 0 3 3 3 2 Sodium:neurotransmitter symporter family GMC_oxred_C PF05199.13 CRK17345.1 - 2.6e-17 63.7 0.1 4.1e-17 63.0 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 CRK17345.1 - 1.2e-08 34.7 0.0 2.5e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 CRK17345.1 - 0.0028 16.8 0.1 0.12 11.4 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pro_dh PF01619.18 CRK17346.1 - 8e-55 186.5 0.0 9e-55 186.3 0.0 1.0 1 0 0 1 1 1 1 Proline dehydrogenase P5CR_dimer PF14748.6 CRK17348.1 - 1.9e-29 101.9 2.6 3.8e-29 101.0 2.6 1.5 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 CRK17348.1 - 1.7e-09 38.2 0.0 4.8e-09 36.7 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 CRK17348.1 - 0.0035 17.4 0.1 0.0074 16.4 0.1 1.5 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fungal_trans PF04082.18 CRK17349.1 - 6.2e-08 32.0 0.1 7.9e-08 31.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain RecG_N PF17190.4 CRK17349.1 - 0.11 13.3 0.1 0.26 12.0 0.1 1.7 2 0 0 2 2 2 0 RecG N-terminal helical domain Aa_trans PF01490.18 CRK17350.1 - 1.9e-36 125.7 32.5 5e-34 117.7 32.5 2.0 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein DUF4059 PF13268.6 CRK17350.1 - 0.6 10.5 6.7 7.4 7.1 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4059) GFA PF04828.14 CRK17351.1 - 3.8e-15 56.0 0.0 6e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme SLATT_fungal PF18142.1 CRK17352.1 - 5.2e-17 61.9 4.6 7.1e-17 61.5 4.1 1.4 1 1 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain Aldo_ket_red PF00248.21 CRK17353.1 - 6.4e-54 183.1 0.0 9.7e-54 182.5 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Lipase_GDSL_2 PF13472.6 CRK17353.1 - 1.3e-20 74.5 0.2 7.5e-20 72.1 0.1 2.3 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 CRK17353.1 - 7.1e-09 35.9 0.0 1.1e-08 35.4 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 CRK17353.1 - 2.8e-06 27.6 0.0 5.5e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family SF3A2 PF16835.5 CRK17355.1 - 6.4e-35 119.4 0.1 1e-34 118.8 0.1 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 CRK17355.1 - 3.5e-06 27.2 0.9 6.9e-06 26.3 0.9 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.9 CRK17355.1 - 9e-05 22.4 0.2 0.00014 21.8 0.2 1.2 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein PRP4 PF08799.11 CRK17355.1 - 0.12 11.9 0.5 0.21 11.2 0.5 1.4 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Pkinase_C PF00433.24 CRK17356.1 - 0.036 14.8 0.6 0.11 13.2 0.6 1.8 1 1 0 1 1 1 0 Protein kinase C terminal domain Tim54 PF11711.8 CRK17357.1 - 3e-25 88.8 0.1 4.3e-25 88.3 0.1 1.2 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 POR_N PF01855.19 CRK17357.1 - 6.3e-05 22.8 0.0 9.7e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg DUF456 PF04306.13 CRK17357.1 - 0.058 13.7 11.4 0.06 13.6 9.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF456) Pkinase PF00069.25 CRK17358.1 - 3.3e-58 197.1 0.0 3.9e-57 193.6 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK17358.1 - 1.3e-26 93.5 0.1 2.4e-20 72.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 CRK17358.1 - 7e-05 21.9 0.0 0.00012 21.2 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CRK17358.1 - 0.00011 22.2 0.2 0.037 13.9 0.2 2.7 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 CRK17358.1 - 0.00075 18.9 0.0 0.0018 17.7 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CRK17358.1 - 0.0013 18.2 0.9 0.0017 17.7 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 CRK17358.1 - 0.055 12.5 0.0 0.093 11.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 CRK17358.1 - 0.19 11.3 0.7 0.89 9.1 0.0 2.1 2 0 0 2 2 2 0 RIO1 family IER PF05760.12 CRK17358.1 - 5.9 7.1 9.0 11 6.2 9.0 1.4 1 0 0 1 1 1 0 Immediate early response protein (IER) Tim54 PF11711.8 CRK17359.1 - 2.3e-142 474.2 3.1 2.9e-142 473.9 3.1 1.1 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Orthopox_F8 PF05886.11 CRK17359.1 - 0.085 13.0 0.7 0.87 9.8 0.8 2.2 2 0 0 2 2 2 0 Orthopoxvirus F8 protein Pex14_N PF04695.13 CRK17359.1 - 0.23 12.1 10.8 1.8 9.2 2.8 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PRCC PF10253.9 CRK17359.1 - 6.1 7.6 15.2 0.099 13.4 5.1 2.5 3 0 0 3 3 3 0 Mitotic checkpoint regulator, MAD2B-interacting Nefa_Nip30_N PF10187.9 CRK17360.1 - 2.5e-30 104.9 16.6 2.5e-30 104.9 16.6 1.8 2 0 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 Glyco_hydro_106 PF17132.4 CRK17360.1 - 0.0096 14.3 0.4 0.013 13.8 0.4 1.1 1 0 0 1 1 1 1 alpha-L-rhamnosidase Tim54 PF11711.8 CRK17361.1 - 1.6e-60 204.9 4.2 2.1e-60 204.5 4.2 1.1 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Orthopox_F8 PF05886.11 CRK17361.1 - 0.025 14.7 0.9 0.43 10.8 0.9 2.4 2 0 0 2 2 2 0 Orthopoxvirus F8 protein E7 PF00527.18 CRK17361.1 - 0.22 11.7 1.1 0.73 10.1 0.1 2.1 2 0 0 2 2 2 0 E7 protein, Early protein Nefa_Nip30_N PF10187.9 CRK17362.1 - 9.9e-31 106.2 16.7 2.1e-30 105.1 16.7 1.5 1 0 0 1 1 1 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF4636 PF15468.6 CRK17362.1 - 0.078 12.7 0.1 0.16 11.7 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4636) zf-HC3 PF16827.5 CRK17362.1 - 0.58 10.4 4.7 3.6 7.9 3.5 2.6 2 0 0 2 2 2 0 zinc-finger GLEYA PF10528.9 CRK17363.1 - 1.8e-17 63.5 0.5 3.4e-17 62.6 0.5 1.5 1 0 0 1 1 1 1 GLEYA domain PA14 PF07691.12 CRK17363.1 - 4.8e-06 26.4 0.0 9.9e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 PA14 domain HET PF06985.11 CRK17364.1 - 1.9e-06 28.3 0.0 0.0045 17.3 0.0 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Cyclin PF08613.11 CRK17365.1 - 4.2e-09 37.0 0.0 9.3e-09 35.9 0.0 1.6 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 CRK17365.1 - 4.5e-05 23.2 0.0 7.7e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Questin_oxidase PF14027.6 CRK17366.1 - 5.2e-44 151.2 1.2 6.7e-44 150.8 1.2 1.1 1 0 0 1 1 1 1 Questin oxidase-like FAD_binding_4 PF01565.23 CRK17367.1 - 4.9e-17 62.0 3.3 9e-17 61.1 3.3 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 CRK17367.1 - 0.089 12.9 0.1 0.17 12.0 0.1 1.5 1 0 0 1 1 1 0 Berberine and berberine like NAD_binding_10 PF13460.6 CRK17368.1 - 1e-06 28.8 0.0 1.9e-05 24.6 0.0 2.2 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 CRK17368.1 - 0.0022 17.6 0.0 0.004 16.7 0.0 1.4 2 0 0 2 2 2 1 NmrA-like family LDcluster4 PF18306.1 CRK17368.1 - 0.015 14.9 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 SLOG cluster4 family PHD PF00628.29 CRK17369.1 - 5.9e-05 22.9 7.7 9.1e-05 22.3 7.7 1.3 1 0 0 1 1 1 1 PHD-finger zf-PHD-like PF15446.6 CRK17369.1 - 0.014 15.0 0.6 0.073 12.7 0.3 1.9 1 1 1 2 2 2 0 PHD/FYVE-zinc-finger like domain Prok-RING_1 PF14446.6 CRK17369.1 - 0.028 14.3 3.3 0.055 13.4 3.3 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 C1_2 PF03107.16 CRK17369.1 - 0.12 12.7 1.9 0.17 12.2 0.4 1.9 2 0 0 2 2 2 0 C1 domain C1_1 PF00130.22 CRK17369.1 - 0.14 12.1 4.2 0.068 13.1 1.2 1.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Glyco_hydro_67M PF07488.12 CRK17370.1 - 8.7e-145 481.8 0.0 1.2e-144 481.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67C PF07477.12 CRK17370.1 - 1.4e-88 296.1 2.6 2.3e-88 295.5 2.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 C-terminus Glyco_hydro_67N PF03648.14 CRK17370.1 - 5.2e-27 94.6 0.0 9.2e-27 93.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus Asn_synthase PF00733.21 CRK17370.1 - 1.3e-17 64.5 2.4 7.1e-09 35.8 0.3 3.2 2 1 1 3 3 3 3 Asparagine synthase GATase_7 PF13537.6 CRK17370.1 - 6.4e-07 29.3 0.0 2.2e-06 27.6 0.0 1.9 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 CRK17370.1 - 0.0017 18.5 0.0 0.0043 17.2 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain Glyco_hydro_20b PF02838.15 CRK17370.1 - 0.0043 17.8 0.2 0.018 15.9 0.1 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 Poxvirus_B22R PF04395.12 CRK17370.1 - 0.022 14.3 0.0 0.038 13.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus B22R protein DUF3700 PF12481.8 CRK17370.1 - 0.098 12.1 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Aluminium induced protein Peptidase_M28 PF04389.17 CRK17371.1 - 3.2e-38 131.4 0.0 4.2e-38 131.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Glyco_hydro_15 PF00723.21 CRK17372.1 - 3.2e-99 332.7 0.0 3.9e-99 332.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.19 CRK17372.1 - 3.5e-35 119.8 0.9 7.8e-35 118.7 0.9 1.6 1 0 0 1 1 1 1 Starch binding domain Isochorismatase PF00857.20 CRK17373.1 - 4.8e-19 69.2 0.0 8.3e-19 68.4 0.0 1.4 1 0 0 1 1 1 1 Isochorismatase family Kelch_4 PF13418.6 CRK17373.1 - 5e-18 64.8 4.7 1e-09 38.2 0.0 5.6 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_3 PF13415.6 CRK17373.1 - 3.1e-15 56.0 2.0 0.0022 18.2 0.0 5.9 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_6 PF13964.6 CRK17373.1 - 1.1e-09 38.2 4.3 0.034 14.4 0.1 4.8 4 1 1 5 5 5 3 Kelch motif Kelch_2 PF07646.15 CRK17373.1 - 2.1e-09 37.0 1.0 0.033 14.2 0.0 4.5 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.25 CRK17373.1 - 5e-07 29.2 0.9 0.073 12.7 0.0 4.6 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.6 CRK17373.1 - 3.4e-05 23.7 2.2 0.8 9.8 0.0 4.2 4 0 0 4 4 4 2 Kelch motif Fungal_trans PF04082.18 CRK17374.1 - 3.7e-10 39.3 0.2 7.9e-10 38.2 0.2 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK17374.1 - 0.00079 19.5 8.9 0.0014 18.7 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 CRK17375.1 - 1.7e-08 34.4 10.2 2.9e-08 33.7 10.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 CRK17375.1 - 2e-05 23.6 0.0 2.8e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 CRK17377.1 - 2.5e-25 89.2 29.2 4.7e-25 88.3 28.7 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 CRK17377.1 - 0.015 14.2 12.7 0.03 13.2 12.7 1.4 1 0 0 1 1 1 0 MFS_1 like family FAD_binding_3 PF01494.19 CRK17379.1 - 4.2e-17 62.4 0.1 9.4e-16 58.0 0.1 2.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 CRK17379.1 - 0.0018 18.0 0.1 0.0053 16.4 0.1 1.7 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CRK17379.1 - 0.0034 17.6 0.0 0.0079 16.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 CRK17379.1 - 0.0095 15.9 0.1 0.033 14.2 0.1 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 CRK17379.1 - 0.016 14.3 0.1 1.7 7.6 0.0 2.6 2 1 0 3 3 3 0 Lycopene cyclase protein Pyr_redox_2 PF07992.14 CRK17379.1 - 0.041 13.1 0.0 5.8 6.1 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 CRK17379.1 - 0.12 12.4 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ATP-cone PF03477.16 CRK17383.1 - 0.025 15.2 0.1 0.17 12.5 0.0 2.0 1 1 1 2 2 2 0 ATP cone domain Baculo_PEP_C PF04513.12 CRK17383.1 - 0.037 14.1 6.4 0.38 10.8 0.9 2.9 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_11 PF13086.6 CRK17388.1 - 1.4e-07 31.6 0.0 1.8e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CRK17388.1 - 0.057 13.1 0.0 0.065 12.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF3455 PF11937.8 CRK17407.1 - 1.2e-20 74.5 0.0 1.3e-20 74.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) Cupin_2 PF07883.11 CRK17423.1 - 0.097 12.4 1.6 1.2 8.8 1.2 2.5 1 1 1 2 2 2 0 Cupin domain KfrA_N PF11740.8 CRK17426.1 - 0.046 14.4 7.1 0.064 13.9 7.1 1.1 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term RR_TM4-6 PF06459.12 CRK17426.1 - 4.3 7.1 12.7 4.9 6.9 12.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 CRK17426.1 - 6.1 5.0 9.3 5.4 5.2 9.3 1.1 1 0 0 1 1 1 0 CDC45-like protein GATase_2 PF00310.21 CRK17427.1 - 7.3e-62 209.4 0.0 8.4e-62 209.2 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Fib_alpha PF08702.10 CRK17431.1 - 0.00022 21.4 16.2 0.006 16.8 5.2 2.5 1 1 1 2 2 2 2 Fibrinogen alpha/beta chain family CEP63 PF17045.5 CRK17431.1 - 0.0022 17.9 26.3 0.0085 16.0 26.3 1.9 1 1 0 1 1 1 1 Centrosomal protein of 63 kDa SlyX PF04102.12 CRK17431.1 - 0.021 15.5 26.0 1.5 9.5 0.0 5.5 3 1 1 5 5 5 0 SlyX DUF2997 PF11211.8 CRK17431.1 - 0.065 13.0 0.9 2.9 7.8 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2997) SATase_N PF06426.14 CRK17431.1 - 0.079 13.4 0.9 1.5 9.2 0.9 2.5 1 1 0 1 1 1 0 Serine acetyltransferase, N-terminal DUF1664 PF07889.12 CRK17431.1 - 0.42 10.7 13.9 0.067 13.2 1.2 2.9 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) CREPT PF16566.5 CRK17431.1 - 0.98 9.6 13.9 0.51 10.5 5.9 2.5 1 1 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour MAD PF05557.13 CRK17431.1 - 1.2 7.5 27.0 2 6.7 26.9 1.4 1 1 0 1 1 1 0 Mitotic checkpoint protein BST2 PF16716.5 CRK17431.1 - 1.4 9.6 24.4 0.64 10.6 1.4 5.1 2 1 3 5 5 5 0 Bone marrow stromal antigen 2 ATG16 PF08614.11 CRK17431.1 - 2.2 8.5 30.6 1.2 9.3 18.4 2.8 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Cortex-I_coil PF09304.10 CRK17431.1 - 3.5 7.9 14.9 0.72 10.1 6.8 3.2 1 1 2 3 3 3 0 Cortexillin I, coiled coil Importin_rep_6 PF18829.1 CRK17431.1 - 4.6 7.4 7.7 0.64 10.2 0.7 2.6 1 1 1 2 2 2 0 Importin repeat 6 ERM PF00769.19 CRK17431.1 - 5.9 6.6 29.3 1.1 9.0 12.5 2.2 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF724 PF05266.14 CRK17431.1 - 5.9 6.7 20.0 0.61 9.9 7.9 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF724) TMPIT PF07851.13 CRK17431.1 - 6.4 5.9 13.5 7.7 5.7 2.1 2.1 1 1 1 2 2 2 0 TMPIT-like protein Tropomyosin_1 PF12718.7 CRK17431.1 - 7.1 6.8 32.3 1.5 9.0 13.6 3.0 1 1 2 3 3 3 0 Tropomyosin like Sugarporin_N PF11471.8 CRK17431.1 - 8 6.5 11.1 0.99 9.4 1.5 3.3 3 0 0 3 3 3 0 Maltoporin periplasmic N-terminal extension Swi5 PF07061.11 CRK17431.1 - 8.7 6.5 17.8 0.69 10.0 0.8 4.5 3 2 0 3 3 3 0 Swi5 DUF3626 PF12294.8 CRK17434.1 - 0.011 14.8 0.1 0.013 14.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3626) eIF3_p135 PF12807.7 CRK17434.1 - 0.046 13.8 0.3 0.061 13.4 0.3 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit 135 Na_Ca_ex PF01699.24 CRK17435.1 - 1.7e-22 80.0 27.1 9.2e-14 51.7 11.1 3.6 5 0 0 5 5 5 2 Sodium/calcium exchanger protein YccF PF03733.13 CRK17435.1 - 4.7e-16 59.2 12.5 4.7e-16 59.2 12.5 4.2 5 0 0 5 5 5 2 Inner membrane component domain AAA PF00004.29 CRK17436.1 - 2.6e-43 147.6 0.0 4.2e-43 146.9 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CRK17436.1 - 6.8e-14 51.4 0.0 1.3e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 CRK17436.1 - 9.9e-08 32.1 0.0 2.5e-07 30.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CRK17436.1 - 1.7e-07 31.6 0.0 2.9e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Prot_ATP_ID_OB PF16450.5 CRK17436.1 - 3.5e-06 26.9 3.3 9.5e-06 25.5 3.3 1.8 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 CRK17436.1 - 5.2e-06 26.9 0.0 0.00011 22.6 0.0 2.5 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 CRK17436.1 - 5e-05 23.6 0.2 0.011 16.1 0.0 2.4 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 CRK17436.1 - 5.8e-05 22.9 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 CRK17436.1 - 0.00066 20.2 0.1 0.016 15.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 CRK17436.1 - 0.001 18.4 0.0 0.002 17.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 CRK17436.1 - 0.0015 18.7 0.0 0.0029 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 CRK17436.1 - 0.0029 17.4 0.0 0.0052 16.5 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 CRK17436.1 - 0.0032 17.3 0.0 0.01 15.7 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 CRK17436.1 - 0.008 15.6 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ATPase PF06745.13 CRK17436.1 - 0.0081 15.5 0.0 0.019 14.3 0.0 1.6 1 0 0 1 1 1 1 KaiC TsaE PF02367.17 CRK17436.1 - 0.011 15.8 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 CRK17436.1 - 0.011 15.9 0.0 0.02 15.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 CRK17436.1 - 0.022 14.0 0.0 0.038 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 CRK17436.1 - 0.024 14.3 0.0 0.097 12.4 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 CRK17436.1 - 0.027 14.0 0.0 0.044 13.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 CRK17436.1 - 0.032 13.7 0.0 0.14 11.6 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein AAA_14 PF13173.6 CRK17436.1 - 0.034 14.2 0.0 0.057 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CRK17436.1 - 0.035 14.5 0.0 0.064 13.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 CRK17436.1 - 0.04 13.6 0.0 0.099 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain HR1 PF02185.16 CRK17436.1 - 0.05 13.7 1.0 0.13 12.4 1.0 1.7 1 0 0 1 1 1 0 Hr1 repeat AAA_25 PF13481.6 CRK17436.1 - 0.053 13.1 0.1 0.17 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 CRK17436.1 - 0.06 12.4 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Prot_ATP_OB_N PF17758.1 CRK17436.1 - 0.074 12.7 0.2 0.28 10.9 0.2 2.0 1 1 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain Zeta_toxin PF06414.12 CRK17436.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DUF2072 PF09845.9 CRK17436.1 - 0.12 12.6 0.1 0.23 11.7 0.1 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein Y_phosphatase PF00102.27 CRK17437.1 - 8.6e-60 202.2 0.0 1.7e-51 175.0 0.0 3.3 2 1 0 2 2 2 2 Protein-tyrosine phosphatase Rhodanese PF00581.20 CRK17437.1 - 3.5e-10 40.4 0.0 1.1e-09 38.7 0.0 1.9 1 0 0 1 1 1 1 Rhodanese-like domain DSPc PF00782.20 CRK17437.1 - 0.029 14.2 0.1 0.072 12.9 0.1 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 CRK17437.1 - 0.035 14.1 0.1 0.074 13.0 0.1 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family AAA PF00004.29 CRK17438.1 - 1.6e-43 148.3 0.0 2.6e-43 147.6 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CRK17438.1 - 6.8e-14 51.4 0.0 1.3e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 CRK17438.1 - 9.3e-08 32.4 0.0 1.8e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 CRK17438.1 - 1.4e-07 31.5 0.0 3.7e-07 30.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Prot_ATP_ID_OB PF16450.5 CRK17438.1 - 3.5e-06 26.8 3.3 9.5e-06 25.5 3.3 1.8 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 CRK17438.1 - 5.1e-06 27.0 0.0 0.00011 22.6 0.0 2.5 2 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 CRK17438.1 - 2.6e-05 24.5 0.2 0.0061 16.8 0.2 2.4 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 CRK17438.1 - 5.8e-05 22.9 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 CRK17438.1 - 0.00068 20.2 0.0 0.019 15.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 CRK17438.1 - 0.001 18.4 0.0 0.002 17.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 CRK17438.1 - 0.0015 18.7 0.0 0.0029 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 CRK17438.1 - 0.0029 17.4 0.0 0.0052 16.5 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 CRK17438.1 - 0.0032 17.3 0.0 0.01 15.7 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 CRK17438.1 - 0.008 15.6 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ATPase PF06745.13 CRK17438.1 - 0.0081 15.5 0.0 0.019 14.3 0.0 1.6 1 0 0 1 1 1 1 KaiC TsaE PF02367.17 CRK17438.1 - 0.01 15.8 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 CRK17438.1 - 0.011 15.9 0.0 0.02 15.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 CRK17438.1 - 0.021 14.0 0.0 0.037 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 CRK17438.1 - 0.022 14.5 0.0 0.097 12.4 0.0 2.0 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 CRK17438.1 - 0.027 14.0 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 CRK17438.1 - 0.03 13.8 0.0 0.14 11.6 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein RNA_helicase PF00910.22 CRK17438.1 - 0.035 14.5 0.0 0.064 13.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 CRK17438.1 - 0.036 13.8 0.0 0.1 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 CRK17438.1 - 0.036 14.1 0.0 0.061 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain HR1 PF02185.16 CRK17438.1 - 0.052 13.7 1.0 0.13 12.4 1.0 1.6 1 0 0 1 1 1 0 Hr1 repeat AAA_25 PF13481.6 CRK17438.1 - 0.053 13.1 0.1 0.17 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 CRK17438.1 - 0.06 12.4 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Prot_ATP_OB_N PF17758.1 CRK17438.1 - 0.074 12.7 0.2 0.28 10.9 0.2 2.0 1 1 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain Zeta_toxin PF06414.12 CRK17438.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DUF2072 PF09845.9 CRK17438.1 - 0.12 12.6 0.1 0.23 11.7 0.1 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein Y_phosphatase PF00102.27 CRK17439.1 - 6.9e-20 71.6 0.0 1.1e-19 70.9 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.20 CRK17439.1 - 2.3e-10 40.9 0.0 5e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Tcp11 PF05794.13 CRK17441.1 - 5.3e-139 464.1 24.2 1e-95 321.4 0.5 4.2 5 0 0 5 5 5 3 T-complex protein 11 Peptidase_M1_N PF17900.1 CRK17441.1 - 2.8e-11 43.9 0.1 5e-11 43.1 0.1 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain MIase PF02426.16 CRK17441.1 - 1.4e-05 25.1 0.6 0.28 11.4 0.1 3.2 2 0 0 2 2 2 2 Muconolactone delta-isomerase DUF2808 PF10989.8 CRK17441.1 - 0.013 15.5 0.1 0.028 14.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2808) DUF1953 PF09196.10 CRK17441.1 - 0.14 12.0 0.0 32 4.4 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1953) DUF3552 PF12072.8 CRK17441.1 - 0.21 11.0 41.7 0.21 11.0 11.4 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3552) DUF5069 PF16798.5 CRK17441.1 - 0.58 10.4 8.2 5.9 7.1 1.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5069) T2SSF PF00482.23 CRK17441.1 - 0.82 9.6 5.5 11 6.0 1.0 3.4 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F Glyco_transf_4 PF13439.6 CRK17443.1 - 1.8e-07 31.3 0.1 2.2e-07 31.0 0.1 1.3 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 CRK17443.1 - 0.00046 20.7 0.0 0.00052 20.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_5 PF16994.5 CRK17443.1 - 0.077 12.6 0.0 0.098 12.3 0.0 1.1 1 0 0 1 1 1 0 Glycosyl-transferase family 4 ERAP1_C PF11838.8 CRK17445.1 - 1.5e-95 320.4 0.0 8.5e-56 189.8 0.0 3.1 2 1 1 3 3 3 2 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 CRK17445.1 - 3.4e-80 268.7 2.9 5.4e-80 268.1 2.9 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 CRK17445.1 - 2.9e-39 135.2 0.3 2.7e-38 132.0 0.2 2.5 2 1 0 2 2 2 1 Peptidase M1 N-terminal domain CaATP_NAI PF12515.8 CRK17445.1 - 0.1 12.2 0.2 8.1 6.2 0.1 2.5 2 0 0 2 2 2 0 Ca2+-ATPase N terminal autoinhibitory domain Glycos_transf_1 PF00534.20 CRK17446.1 - 3.5e-53 179.7 0.0 8.1e-33 113.4 0.0 3.2 2 1 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CRK17446.1 - 3.1e-26 92.4 1.1 4.4e-15 56.3 0.1 2.8 2 1 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 CRK17446.1 - 9.9e-08 32.3 0.0 0.024 15.0 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 ABATE PF07336.11 CRK17446.1 - 0.0008 20.1 4.7 0.72 10.5 0.4 2.7 2 0 0 2 2 2 2 Putative stress-induced transcription regulator ArsP_1 PF03773.13 CRK17446.1 - 0.001 18.3 1.1 0.98 8.5 0.1 2.4 2 0 0 2 2 2 2 Predicted permease TraE PF05309.11 CRK17446.1 - 0.0044 16.4 0.0 3.6 6.9 0.0 2.3 2 0 0 2 2 2 2 TraE protein Comm PF15957.5 CRK17446.1 - 0.099 13.0 0.3 11 6.4 0.0 2.3 2 0 0 2 2 2 0 Commissureless Glyoxalase_6 PF18029.1 CRK17446.1 - 0.2 12.5 4.9 11 6.8 0.2 3.0 2 1 0 2 2 2 0 Glyoxalase-like domain Auxin_repressed PF05564.12 CRK17446.1 - 0.4 11.4 1.6 41 4.9 0.0 2.7 3 0 0 3 3 3 0 Dormancy/auxin associated protein Peptidase_M1 PF01433.20 CRK17448.1 - 1.8e-41 142.1 0.7 2.4e-41 141.7 0.7 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 CRK17448.1 - 2e-21 76.9 0.0 3.2e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Methyltransf_11 PF08241.12 CRK17449.1 - 1.2e-07 32.3 0.1 2e-07 31.6 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK17449.1 - 1e-06 29.4 0.1 1.9e-06 28.5 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK17449.1 - 8.8e-06 25.6 0.0 1.2e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain NAS PF03059.16 CRK17449.1 - 0.1 11.9 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Nicotianamine synthase protein Ubie_methyltran PF01209.18 CRK17449.1 - 0.18 11.1 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Glyco_transf_4 PF13439.6 CRK17451.1 - 2.4e-07 30.9 0.0 3e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 CRK17451.1 - 0.00031 21.2 0.2 0.00037 21.0 0.2 1.1 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_5 PF16994.5 CRK17451.1 - 0.1 12.2 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Glycosyl-transferase family 4 NUDIX PF00293.28 CRK17453.1 - 1.1e-13 51.4 0.2 3e-13 50.0 0.1 1.8 2 0 0 2 2 2 1 NUDIX domain Methyltransf_11 PF08241.12 CRK17453.1 - 9.7e-08 32.6 0.1 2.2e-07 31.4 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK17453.1 - 1.3e-06 29.0 0.1 3.6e-06 27.6 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK17453.1 - 3.6e-05 23.6 0.0 6.2e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NAS PF03059.16 CRK17453.1 - 0.067 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Nicotianamine synthase protein Pec_lyase_C PF00544.19 CRK17455.1 - 1.3e-18 67.4 6.7 9.1e-17 61.3 6.6 2.3 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 CRK17455.1 - 1.3e-05 25.1 15.7 3.1e-05 23.9 8.3 2.3 1 1 1 2 2 2 2 Right handed beta helix region Polysacc_deac_1 PF01522.21 CRK17457.1 - 6.7e-30 103.5 0.0 1e-29 102.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 CRK17457.1 - 1.9e-07 30.6 0.0 2e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 DUF2334 PF10096.9 CRK17457.1 - 0.00034 20.3 0.0 0.00052 19.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Sugar_tr PF00083.24 CRK17458.1 - 1.2e-95 321.0 16.2 1.4e-95 320.8 16.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK17458.1 - 1.2e-26 93.5 30.4 5.9e-20 71.5 12.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CRK17458.1 - 0.00073 18.1 1.2 0.00073 18.1 1.2 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) N2227 PF07942.12 CRK17459.1 - 3.5e-58 196.9 0.0 5.4e-58 196.3 0.0 1.3 1 0 0 1 1 1 1 N2227-like protein DUF1304 PF06993.12 CRK17459.1 - 6.5e-42 142.0 4.0 1.3e-41 141.0 4.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1304) Methyltransf_11 PF08241.12 CRK17459.1 - 0.0074 16.9 0.2 0.035 14.8 0.1 2.4 2 1 0 2 2 2 1 Methyltransferase domain DUF2313 PF10076.9 CRK17459.1 - 0.02 14.8 0.0 0.1 12.5 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein conserved in bacteria (DUF2313) Tyrosinase PF00264.20 CRK17460.1 - 3.6e-30 105.9 0.9 3.9e-29 102.5 0.9 2.0 1 1 0 1 1 1 1 Common central domain of tyrosinase Peptidase_M14 PF00246.24 CRK17461.1 - 1.1e-10 41.8 0.0 1.6e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase DUF2817 PF10994.8 CRK17461.1 - 0.13 11.7 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2817) CBM_20 PF00686.19 CRK17462.1 - 2.1e-33 114.1 0.2 3.6e-33 113.3 0.2 1.4 1 0 0 1 1 1 1 Starch binding domain Peptidase_M14 PF00246.24 CRK17463.1 - 3.3e-21 76.3 0.0 5.3e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase Cofilin_ADF PF00241.20 CRK17465.1 - 1.1e-23 83.4 0.0 1.2e-23 83.2 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF3656 PF12392.8 CRK17465.1 - 0.14 12.9 0.0 0.18 12.5 0.0 1.3 1 0 0 1 1 1 0 Collagenase Peptidase_S8 PF00082.22 CRK17466.1 - 3.8e-36 124.9 2.2 5.4e-36 124.4 2.2 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 CRK17466.1 - 0.0017 19.0 0.0 0.0036 17.9 0.0 1.6 1 1 0 1 1 1 1 Peptidase inhibitor I9 Abhydrolase_6 PF12697.7 CRK17466.1 - 0.011 16.3 0.7 0.011 16.3 0.7 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF4236 PF14020.6 CRK17468.1 - 3.1 8.4 7.8 6.8 7.3 0.1 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF4236) Glyco_tranf_2_3 PF13641.6 CRK17469.1 - 1.7e-15 57.6 0.2 2.3e-15 57.1 0.2 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 CRK17469.1 - 9.8e-05 22.2 0.1 0.00015 21.6 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Phytase PF02333.15 CRK17471.1 - 0.15 11.0 0.1 0.21 10.5 0.1 1.2 1 0 0 1 1 1 0 Phytase AAA PF00004.29 CRK17473.1 - 6.2e-17 62.3 0.0 9.7e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) CAP_N PF01213.19 CRK17473.1 - 0.28 10.6 0.5 0.55 9.7 0.5 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal TFIID-18kDa PF02269.16 CRK17474.1 - 7.2e-23 80.4 1.1 1.6e-22 79.3 0.0 2.1 3 0 0 3 3 3 1 Transcription initiation factor IID, 18kD subunit FAD_binding_4 PF01565.23 CRK17475.1 - 1.6e-07 31.1 0.1 3.1e-07 30.2 0.1 1.4 1 1 0 1 1 1 1 FAD binding domain GFA PF04828.14 CRK17476.1 - 6.6e-11 42.4 5.3 1.9e-06 28.1 0.4 3.9 2 2 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme FAD_binding_4 PF01565.23 CRK17477.1 - 2.5e-05 24.0 0.0 5.5e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Glyco_hydro_7 PF00840.20 CRK17478.1 - 3.1e-59 200.8 0.0 3.4e-59 200.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Zn_clus PF00172.18 CRK17480.1 - 1.1e-09 38.2 6.7 1.7e-09 37.6 6.7 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GET2 PF08690.10 CRK17485.1 - 0.22 11.1 0.0 0.3 10.7 0.0 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 P34-Arc PF04045.14 CRK17502.1 - 4.1e-07 30.0 0.0 6.3e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc HEAT PF02985.22 CRK17502.1 - 0.18 12.2 0.1 4.3 7.9 0.0 3.0 3 0 0 3 3 3 0 HEAT repeat Pep3_Vps18 PF05131.14 CRK17514.1 - 1.3e-45 154.8 0.2 3.5e-45 153.5 0.0 1.8 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 CRK17514.1 - 1.8e-07 31.1 1.7 0.00011 22.1 0.0 2.9 3 0 0 3 3 3 2 Region in Clathrin and VPS DUF2175 PF09943.9 CRK17514.1 - 0.00022 21.5 2.8 0.0024 18.2 0.1 2.6 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2175) zf-C3HC4_2 PF13923.6 CRK17514.1 - 0.00022 21.0 0.6 0.00047 19.9 0.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CRK17514.1 - 0.00078 19.3 0.4 0.00078 19.3 0.4 1.7 2 0 0 2 2 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 CRK17514.1 - 0.0012 18.5 0.1 0.0024 17.5 0.1 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_2 PF13639.6 CRK17514.1 - 0.0025 18.1 0.5 0.0061 16.9 0.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 CRK17514.1 - 0.008 16.2 0.6 0.019 15.0 0.6 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Vps39_2 PF10367.9 CRK17514.1 - 0.015 15.7 0.0 0.037 14.5 0.0 1.7 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 DUF2570 PF10828.8 CRK17514.1 - 0.043 13.6 1.0 3.9 7.4 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2570) zf-rbx1 PF12678.7 CRK17514.1 - 0.1 12.9 0.2 0.25 11.7 0.2 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain LON_substr_bdg PF02190.16 CRK17514.1 - 0.14 12.0 0.4 0.36 10.7 0.4 1.6 1 0 0 1 1 1 0 ATP-dependent protease La (LON) substrate-binding domain zf-C3H2C3 PF17122.5 CRK17514.1 - 0.23 11.6 6.9 0.038 14.0 2.5 2.0 2 0 0 2 2 2 0 Zinc-finger zf-RING_11 PF17123.5 CRK17514.1 - 0.71 9.7 11.2 0.036 13.8 4.3 2.2 2 0 0 2 2 2 0 RING-like zinc finger zf-C3HC4 PF00097.25 CRK17514.1 - 3.2 7.7 5.0 0.3 11.0 0.2 1.7 2 0 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) GTP_EFTU PF00009.27 CRK17516.1 - 3.3e-12 46.4 0.0 4.3e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 CRK17516.1 - 9.3e-10 38.8 0.9 2e-09 37.7 0.3 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 PduV-EutP PF10662.9 CRK17516.1 - 0.03 14.1 0.2 0.53 10.0 0.2 2.3 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Na_H_Exchanger PF00999.21 CRK17518.1 - 3e-22 78.9 8.5 3.5e-22 78.7 8.5 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Bac_rhodopsin PF01036.18 CRK17520.1 - 4.8e-54 183.3 5.9 5.7e-54 183.0 5.9 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF3810 PF12725.7 CRK17520.1 - 4.1 6.7 4.7 5.7 6.2 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Cation_ATPase_C PF00689.21 CRK17521.1 - 1.6e-29 102.9 0.4 2.8e-29 102.1 0.4 1.4 1 1 0 1 1 1 1 Cation transporting ATPase, C-terminus ABC_tran PF00005.27 CRK17524.1 - 4.7e-53 179.4 0.0 5.7e-32 111.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 CRK17524.1 - 1.2e-42 146.5 13.6 1.7e-42 146.0 13.6 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 CRK17524.1 - 4.7e-13 49.1 0.5 0.00018 21.0 0.0 3.2 3 0 0 3 3 3 3 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 CRK17524.1 - 1e-06 27.9 0.0 0.035 12.9 0.0 2.3 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA PF00004.29 CRK17524.1 - 0.00037 20.9 0.2 14 6.1 0.0 3.5 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 CRK17524.1 - 0.0009 19.4 3.3 1.4 9.2 0.4 4.2 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 CRK17524.1 - 0.00096 19.6 0.1 0.013 15.9 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CRK17524.1 - 0.018 15.3 0.2 0.31 11.3 0.0 2.8 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 CRK17524.1 - 0.066 12.8 0.2 0.73 9.4 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_21 PF13304.6 CRK17524.1 - 0.11 12.3 0.1 2.7 7.7 0.0 2.5 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 CRK17524.1 - 0.11 12.2 0.1 0.23 11.1 0.1 1.4 1 0 0 1 1 1 0 AAA ATPase domain adh_short_C2 PF13561.6 CRK17525.1 - 5.4e-35 121.0 0.2 1e-34 120.1 0.2 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRK17525.1 - 1.5e-30 106.1 0.0 2.7e-30 105.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Fungal_trans PF04082.18 CRK17525.1 - 1.8e-13 50.1 0.1 3.4e-13 49.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 CRK17525.1 - 1.7e-11 43.9 8.5 6.1e-05 23.3 0.2 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CRK17525.1 - 1.3e-07 31.9 7.3 0.012 16.4 0.1 3.3 2 0 0 2 2 2 2 C2H2-type zinc finger Zn_clus PF00172.18 CRK17525.1 - 6e-05 23.1 9.6 6e-05 23.1 9.6 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-H2C2_2 PF13465.6 CRK17525.1 - 0.00019 21.7 6.3 0.0009 19.6 0.3 3.3 3 0 0 3 3 3 1 Zinc-finger double domain KR PF08659.10 CRK17525.1 - 0.00085 19.3 0.2 0.0027 17.6 0.2 1.7 1 1 0 1 1 1 1 KR domain zf-C2H2_jaz PF12171.8 CRK17525.1 - 0.0057 16.9 4.8 0.42 11.0 0.1 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CRK17525.1 - 0.024 15.0 3.1 2.7 8.5 1.2 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 CRK17525.1 - 0.065 13.0 5.1 4.2 7.2 0.1 2.8 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-Di19 PF05605.12 CRK17525.1 - 0.13 12.6 2.1 0.35 11.2 2.1 1.8 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 CRK17525.1 - 0.46 10.5 3.4 0.25 11.4 0.1 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-BED PF02892.15 CRK17525.1 - 0.69 10.0 3.3 8.3 6.5 0.9 2.5 1 1 1 2 2 2 0 BED zinc finger dbPDZ_assoc PF16610.5 CRK17525.1 - 1.3 9.3 6.3 3.6 7.9 6.3 1.8 1 0 0 1 1 1 0 Unstructured region between two PDZ domains on Dlg5 tRNA-synt_His PF13393.6 CRK17526.1 - 2.1e-34 119.2 0.0 3.9e-28 98.6 0.0 2.2 2 0 0 2 2 2 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 CRK17526.1 - 2.2e-12 46.9 0.0 4.2e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 CRK17526.1 - 0.00011 22.2 0.0 0.00028 20.9 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.20 CRK17526.1 - 0.00045 19.4 0.0 0.0014 17.8 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) SLAC1 PF03595.17 CRK17527.1 - 1.5e-93 313.6 55.2 1.7e-93 313.5 55.2 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DHC PF09626.10 CRK17528.1 - 0.087 13.7 0.0 2.4 9.1 0.0 2.3 2 0 0 2 2 2 0 Dihaem cytochrome c Pkinase PF00069.25 CRK17529.1 - 1.1e-68 231.4 0.0 1.6e-68 230.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK17529.1 - 9.5e-35 120.1 0.3 2.2e-34 118.9 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CRK17529.1 - 1.3e-05 24.7 0.0 2.2e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CRK17529.1 - 0.0002 20.8 0.1 0.00052 19.4 0.1 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 CRK17529.1 - 0.012 15.2 0.1 0.1 12.1 0.1 2.5 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL APH PF01636.23 CRK17529.1 - 0.1 12.5 0.0 0.74 9.7 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Amino_oxidase PF01593.24 CRK17530.1 - 1.5e-81 275.0 0.1 4.2e-80 270.2 0.1 2.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase HMG_box PF00505.19 CRK17530.1 - 7.9e-08 32.6 3.1 7.9e-08 32.6 3.1 2.3 2 0 0 2 2 2 1 HMG (high mobility group) box NAD_binding_8 PF13450.6 CRK17530.1 - 2.2e-07 31.0 0.0 5.5e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HMG_box_2 PF09011.10 CRK17530.1 - 7.5e-07 29.7 2.3 1.7e-06 28.5 2.3 1.6 1 0 0 1 1 1 1 HMG-box domain Pyr_redox_2 PF07992.14 CRK17530.1 - 5e-06 26.0 0.0 0.00054 19.3 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CRK17530.1 - 0.0012 18.5 0.0 0.0025 17.5 0.0 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 CRK17530.1 - 0.12 13.0 0.1 0.34 11.5 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ATP-synt PF00231.19 CRK17531.1 - 2.9e-79 266.7 0.2 3.5e-79 266.4 0.2 1.0 1 0 0 1 1 1 1 ATP synthase Topoisom_I PF01028.20 CRK17532.1 - 1.6e-95 318.8 5.2 3.9e-95 317.5 5.2 1.7 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 CRK17532.1 - 7.3e-89 296.9 8.5 7.3e-89 296.9 8.5 2.9 4 0 0 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 CRK17532.1 - 6.3e-31 106.1 0.2 2.8e-30 104.0 0.2 2.3 1 0 0 1 1 1 1 C-terminal topoisomerase domain Glyco_hydro_16 PF00722.21 CRK17533.1 - 4.3e-42 143.6 0.1 6.4e-42 143.0 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 tRNA-synt_2b PF00587.25 CRK17534.1 - 3.7e-33 115.0 0.0 5.8e-33 114.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Aminotran_1_2 PF00155.21 CRK17534.1 - 3.1e-14 52.9 0.0 4.8e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Seryl_tRNA_N PF02403.22 CRK17534.1 - 5.3e-12 45.9 5.7 1.2e-11 44.8 5.7 1.6 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Aminotran_MocR PF12897.7 CRK17534.1 - 2.3e-06 26.7 0.0 4.2e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase DegT_DnrJ_EryC1 PF01041.17 CRK17534.1 - 0.061 12.6 0.0 0.46 9.7 0.0 2.1 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Amino_oxidase PF01593.24 CRK17535.1 - 2.6e-23 83.1 0.0 3.6e-23 82.6 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CRK17535.1 - 2.7e-12 46.7 0.0 6.9e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain zf-CCCH_2 PF14608.6 CRK17535.1 - 3.4e-08 33.7 64.1 0.00098 19.5 14.3 5.7 5 0 0 5 5 5 4 RNA-binding, Nab2-type zinc finger DAO PF01266.24 CRK17535.1 - 3.9e-08 33.3 0.5 3.5e-07 30.1 0.5 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 CRK17535.1 - 6e-05 23.5 0.2 0.006 17.1 0.1 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CRK17535.1 - 0.00011 21.5 0.1 0.0044 16.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Nab2 PF11517.8 CRK17535.1 - 0.00013 22.2 0.2 0.00027 21.2 0.2 1.4 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) NAD_binding_9 PF13454.6 CRK17535.1 - 0.0045 17.0 0.0 0.016 15.2 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding MCRA PF06100.11 CRK17535.1 - 0.0054 15.6 0.0 0.0093 14.8 0.0 1.3 1 0 0 1 1 1 1 MCRA family Thi4 PF01946.17 CRK17535.1 - 0.018 14.3 0.0 0.033 13.4 0.0 1.3 1 0 0 1 1 1 0 Thi4 family G6PD_C PF02781.16 CRK17536.1 - 4.9e-114 380.4 0.0 7.9e-114 379.7 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain Med14 PF08638.11 CRK17536.1 - 4.4e-64 215.4 1.2 5e-64 215.2 0.0 1.8 2 0 0 2 2 2 1 Mediator complex subunit MED14 G6PD_N PF00479.22 CRK17536.1 - 1.1e-58 198.8 0.0 3.4e-58 197.2 0.0 1.9 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, NAD binding domain zf-CCCH_2 PF14608.6 CRK17536.1 - 1.3e-06 28.6 64.1 0.002 18.5 14.3 5.6 5 0 0 5 5 5 4 RNA-binding, Nab2-type zinc finger Nab2 PF11517.8 CRK17536.1 - 0.00025 21.3 0.2 0.00057 20.1 0.2 1.5 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Phage_connect_1 PF05135.13 CRK17536.1 - 0.093 13.2 0.1 0.31 11.6 0.1 1.9 1 0 0 1 1 1 0 Phage gp6-like head-tail connector protein G6PD_C PF02781.16 CRK17538.1 - 3.5e-114 380.9 0.0 5.8e-114 380.2 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain Med14 PF08638.11 CRK17538.1 - 5.6e-65 218.4 0.0 1.2e-64 217.3 0.0 1.6 1 0 0 1 1 1 1 Mediator complex subunit MED14 G6PD_N PF00479.22 CRK17538.1 - 6.2e-59 199.6 0.0 3.2e-58 197.3 0.0 2.2 3 0 0 3 3 3 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Phage_connect_1 PF05135.13 CRK17538.1 - 0.027 15.0 0.4 0.14 12.7 0.1 2.3 2 0 0 2 2 2 0 Phage gp6-like head-tail connector protein RNase_H2-Ydr279 PF09468.10 CRK17538.1 - 0.16 12.1 0.1 0.38 10.9 0.1 1.6 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) wHTH domain Ribosomal_L35Ae PF01247.18 CRK17539.1 - 1.1e-42 144.1 0.6 1.3e-42 143.9 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 CRK17539.1 - 0.00021 21.4 0.1 0.17 12.1 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain Ribosomal_L35Ae PF01247.18 CRK17540.1 - 1.1e-42 144.1 0.6 1.3e-42 143.9 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 CRK17540.1 - 0.00021 21.4 0.1 0.17 12.1 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain EGF_Tenascin PF18720.1 CRK17541.1 - 0.018 15.1 3.1 4.3 7.5 0.1 2.9 3 0 0 3 3 3 0 Tenascin EGF domain DUF2406 PF10295.9 CRK17543.1 - 1.7e-26 92.7 0.4 1.7e-26 92.7 0.4 2.8 2 0 0 2 2 2 1 Uncharacterised protein (DUF2406) dsrm PF00035.26 CRK17543.1 - 0.04 14.6 6.7 3.4 8.5 0.8 2.7 2 0 0 2 2 2 0 Double-stranded RNA binding motif VMA21 PF09446.10 CRK17544.1 - 1.2e-13 50.9 12.7 1.7e-13 50.5 12.7 1.2 1 0 0 1 1 1 1 VMA21-like domain DUF3602 PF12223.8 CRK17545.1 - 3.8e-25 88.3 24.8 1.1e-20 74.0 8.4 2.9 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) SNF2_N PF00176.23 CRK17546.1 - 3e-54 184.1 0.0 4.5e-54 183.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CRK17546.1 - 3.1e-18 66.2 0.1 7.2e-18 65.0 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CRK17546.1 - 1.9e-07 31.2 0.1 4.1e-06 26.9 0.0 2.9 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CRK17546.1 - 2.6e-05 23.5 0.0 5.7e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase TK PF00265.18 CRK17546.1 - 0.16 11.8 6.2 1.1 9.1 0.0 2.9 2 1 0 2 2 2 0 Thymidine kinase DUF3602 PF12223.8 CRK17547.1 - 1.8e-21 76.5 18.4 2.5e-20 72.8 9.7 2.6 2 1 1 3 3 3 2 Protein of unknown function (DUF3602) F_actin_cap_B PF01115.17 CRK17548.1 - 3.3e-88 295.3 0.0 4.4e-88 294.9 0.0 1.1 1 0 0 1 1 1 1 F-actin capping protein, beta subunit HEAT_2 PF13646.6 CRK17548.1 - 0.12 12.8 1.5 0.26 11.7 1.5 1.5 1 0 0 1 1 1 0 HEAT repeats DUF4350 PF14258.6 CRK17549.1 - 0.097 13.1 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4350) RabGAP-TBC PF00566.18 CRK17558.1 - 3.8e-21 75.7 0.0 5.2e-21 75.3 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ddrB-ParB PF18763.1 CRK17558.1 - 0.13 12.4 0.2 0.27 11.3 0.2 1.5 1 0 0 1 1 1 0 ddrB-like ParB superfamily domain Glyco_hydro_3 PF00933.21 CRK17562.1 - 4.7e-21 75.5 0.0 5e-21 75.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_31 PF01055.26 CRK17563.1 - 1.5e-23 83.7 0.0 1.8e-23 83.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NARP1 PF12569.8 CRK17581.1 - 1.4e-113 380.5 10.6 1.8e-113 380.2 10.6 1.0 1 0 0 1 1 1 1 NMDA receptor-regulated protein 1 ANAPC3 PF12895.7 CRK17581.1 - 0.018 15.3 0.9 0.055 13.7 0.1 2.2 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 CRK17581.1 - 0.033 14.7 0.0 0.033 14.7 0.0 4.1 4 2 2 6 6 6 0 Tetratricopeptide repeat DUF4718 PF15842.5 CRK17581.1 - 0.084 12.7 1.0 0.16 11.8 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) TPR_17 PF13431.6 CRK17581.1 - 0.15 12.5 2.2 4 8.0 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 CRK17581.1 - 0.22 12.4 0.2 0.22 12.4 0.2 5.3 4 2 2 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 CRK17581.1 - 0.36 11.1 14.7 0.56 10.5 0.0 5.8 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 CRK17581.1 - 0.38 10.9 4.6 1.4 9.1 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat MFS_1 PF07690.16 CRK17596.1 - 0.0047 15.9 0.2 0.0057 15.6 0.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF5391 PF17369.2 CRK17596.1 - 0.06 13.4 0.0 0.083 12.9 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5391) Peptidase_C13 PF01650.18 CRK17602.1 - 1.3e-33 116.6 0.2 1.6e-33 116.3 0.2 1.0 1 0 0 1 1 1 1 Peptidase C13 family SHE3 PF17078.5 CRK17604.1 - 0.002 17.9 5.1 0.0022 17.7 4.3 1.4 1 1 0 1 1 1 1 SWI5-dependent HO expression protein 3 Csm1_N PF18504.1 CRK17604.1 - 0.003 17.9 1.0 0.0064 16.8 1.0 1.5 1 0 0 1 1 1 1 Csm1 N-terminal domain Sec2p PF06428.11 CRK17604.1 - 0.0031 17.5 6.4 0.005 16.8 5.9 1.6 1 1 0 1 1 1 1 GDP/GTP exchange factor Sec2p Spc7 PF08317.11 CRK17604.1 - 0.0044 15.9 2.0 0.0055 15.6 2.0 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein CENP-K PF11802.8 CRK17604.1 - 0.0055 16.3 0.5 0.0061 16.2 0.5 1.0 1 0 0 1 1 1 1 Centromere-associated protein K Bap31_Bap29_C PF18035.1 CRK17604.1 - 0.0099 15.9 4.1 0.017 15.1 4.1 1.4 1 0 0 1 1 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain SlyX PF04102.12 CRK17604.1 - 0.011 16.3 2.3 0.05 14.2 0.3 2.4 2 1 0 2 2 2 0 SlyX IFT57 PF10498.9 CRK17604.1 - 0.015 14.3 2.8 0.025 13.6 2.4 1.6 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 ADIP PF11559.8 CRK17604.1 - 0.036 14.1 3.7 0.045 13.9 3.7 1.3 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding YojJ PF10372.9 CRK17604.1 - 0.04 14.0 1.5 8.3 6.6 0.0 2.6 1 1 1 2 2 2 0 Bacterial membrane-spanning protein N-terminus Nup54 PF13874.6 CRK17604.1 - 0.049 13.7 1.7 0.067 13.3 0.9 1.6 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 HAUS-augmin3 PF14932.6 CRK17604.1 - 0.064 12.8 3.3 0.08 12.5 3.3 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DHR10 PF18595.1 CRK17604.1 - 0.074 13.1 7.2 0.039 14.0 3.4 1.9 1 1 0 2 2 2 0 Designed helical repeat protein 10 domain Cluap1 PF10234.9 CRK17604.1 - 0.1 12.0 5.2 0.15 11.5 5.2 1.3 1 1 0 1 1 1 0 Clusterin-associated protein-1 RNA_polI_A14 PF08203.11 CRK17604.1 - 0.1 13.3 0.5 3.9 8.3 0.1 2.3 1 1 1 2 2 2 0 Yeast RNA polymerase I subunit RPA14 APG6_N PF17675.1 CRK17604.1 - 0.14 12.7 8.4 0.22 12.1 8.4 1.3 1 1 0 1 1 1 0 Apg6 coiled-coil region TolA_bind_tri PF16331.5 CRK17604.1 - 0.15 12.2 5.6 0.23 11.6 1.7 2.1 2 0 0 2 2 2 0 TolA binding protein trimerisation CHDCT2 PF08074.11 CRK17604.1 - 0.16 12.1 2.8 1 9.6 2.6 1.8 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain Cnn_1N PF07989.11 CRK17604.1 - 0.18 12.0 4.0 0.28 11.3 1.4 2.3 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 XhlA PF10779.9 CRK17604.1 - 0.2 11.9 1.6 0.49 10.6 1.6 1.6 1 0 0 1 1 1 0 Haemolysin XhlA YabA PF06156.13 CRK17604.1 - 0.2 12.3 2.8 0.23 12.1 1.1 1.8 1 1 1 2 2 2 0 Initiation control protein YabA DUF724 PF05266.14 CRK17604.1 - 0.24 11.2 3.1 0.27 11.1 3.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF724) V_ATPase_I PF01496.19 CRK17604.1 - 0.25 9.2 0.6 0.26 9.2 0.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4239 PF14023.6 CRK17604.1 - 0.26 11.0 2.1 0.3 10.8 2.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) Mod_r PF07200.13 CRK17604.1 - 0.3 11.2 6.0 0.4 10.8 6.0 1.3 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DUF4140 PF13600.6 CRK17604.1 - 0.31 11.5 4.0 1.8 9.1 4.0 2.1 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Spc24 PF08286.11 CRK17604.1 - 1.8 8.9 5.7 2.2 8.5 3.8 2.0 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Peptidase_S8 PF00082.22 CRK17608.1 - 2.9e-45 154.8 0.3 5.1e-45 154.0 0.3 1.4 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 CRK17608.1 - 1.5e-07 32.1 0.0 3.5e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 Fn3-like domain Lactamase_B PF00753.27 CRK17609.1 - 3.1e-09 37.1 0.5 6.1e-09 36.2 0.5 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CRK17609.1 - 0.00097 18.7 1.2 0.034 13.7 1.2 2.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Cu_amine_oxid PF01179.20 CRK17610.1 - 3.7e-160 533.3 0.0 4.7e-160 533.0 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 CRK17610.1 - 1.3e-21 76.9 0.4 2.6e-21 75.9 0.4 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 CRK17610.1 - 8.7e-13 48.3 0.0 1.5e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Exo_endo_phos PF03372.23 CRK17612.1 - 4.9e-11 42.6 1.1 1.9e-10 40.6 1.1 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Peptidase_S8 PF00082.22 CRK17614.1 - 3.1e-45 154.7 0.0 7e-45 153.6 0.0 1.5 1 1 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 CRK17614.1 - 7.5e-05 23.4 0.0 0.00068 20.3 0.0 2.5 2 0 0 2 2 2 1 Fn3-like domain PA PF02225.22 CRK17614.1 - 0.0005 20.0 0.4 0.0005 20.0 0.4 2.5 2 0 0 2 2 2 1 PA domain Inhibitor_I9 PF05922.16 CRK17614.1 - 0.0028 18.3 0.1 0.0068 17.1 0.1 1.7 1 0 0 1 1 1 1 Peptidase inhibitor I9 DUF4232 PF14016.6 CRK17614.1 - 0.25 11.5 1.5 4.2 7.5 0.0 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF4232) Toxin_10 PF05431.11 CRK17615.1 - 0.023 14.1 0.2 0.039 13.4 0.2 1.3 1 0 0 1 1 1 0 Insecticidal Crystal Toxin, P42 TANGO2 PF05742.12 CRK17616.1 - 3.2e-65 220.7 0.0 3.7e-65 220.5 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 Tfb2 PF03849.14 CRK17618.1 - 7.4e-124 413.3 0.0 8.7e-124 413.1 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 CRK17618.1 - 7.4e-22 77.6 2.0 1.4e-21 76.6 2.0 1.5 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 CRK17618.1 - 0.00012 22.3 0.0 0.00029 21.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain 4HBT PF03061.22 CRK17619.1 - 5.4e-13 49.1 0.2 1.5e-12 47.7 0.2 1.8 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 CRK17619.1 - 0.0007 19.9 0.1 0.027 14.7 0.0 2.2 2 0 0 2 2 2 1 Thioesterase-like superfamily DUF4442 PF14539.6 CRK17619.1 - 0.0041 17.3 0.0 0.0074 16.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) DHHC PF01529.20 CRK17620.1 - 7.5 6.7 5.7 5.5 7.1 0.2 2.5 2 1 1 3 3 3 0 DHHC palmitoyltransferase Acetyltransf_6 PF13480.7 CRK17621.1 - 0.19 11.9 5.4 0.84 9.8 0.6 2.7 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain NAD_kinase PF01513.21 CRK17622.1 - 2.2e-49 168.3 0.0 3.9e-49 167.4 0.0 1.3 1 0 0 1 1 1 1 ATP-NAD kinase adh_short PF00106.25 CRK17622.1 - 7.2e-18 64.7 0.1 1.2e-17 64.1 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK17622.1 - 6.7e-13 48.7 0.0 1.1e-12 48.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK17622.1 - 3.2e-05 23.9 0.1 9.4e-05 22.4 0.1 1.7 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 CRK17622.1 - 0.0077 15.4 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein FAD_binding_4 PF01565.23 CRK17623.1 - 8.3e-17 61.2 0.2 2e-16 60.0 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 CRK17623.1 - 4.8e-10 39.4 2.0 9.3e-10 38.5 2.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Lactonase PF10282.9 CRK17624.1 - 2.7e-70 237.3 0.0 3.6e-70 236.9 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller He_PIG PF05345.12 CRK17624.1 - 0.13 12.5 2.5 0.38 11.0 1.3 2.5 2 0 0 2 2 2 0 Putative Ig domain CAF1-p150_N PF15557.6 CRK17625.1 - 0.2 11.6 3.9 0.33 10.9 3.9 1.2 1 0 0 1 1 1 0 CAF1 complex subunit p150, region binding to PCNA RNA_polI_A14 PF08203.11 CRK17625.1 - 4 8.2 7.7 5.9 7.7 6.5 2.0 1 1 0 1 1 1 0 Yeast RNA polymerase I subunit RPA14 Glyco_hydro_35 PF01301.19 CRK17627.1 - 5.1e-91 305.6 0.7 6.7e-91 305.2 0.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.9 CRK17627.1 - 9e-60 201.6 0.3 1.6e-59 200.8 0.3 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.6 CRK17627.1 - 4.8e-56 188.2 0.1 7.7e-31 107.0 0.0 2.7 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.6 CRK17627.1 - 1.3e-23 82.3 0.1 2.8e-23 81.3 0.1 1.6 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Glyco_hydro_42 PF02449.15 CRK17627.1 - 0.0027 17.1 0.0 0.016 14.6 0.0 2.1 1 1 0 1 1 1 1 Beta-galactosidase Aa_trans PF01490.18 CRK17628.1 - 8.2e-42 143.3 30.9 9.4e-42 143.2 30.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CAAD PF14159.6 CRK17628.1 - 0.021 14.6 0.6 0.14 12.0 0.6 2.5 1 0 0 1 1 1 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase DUF5337 PF17272.2 CRK17628.1 - 6.6 6.6 9.9 16 5.4 5.7 2.9 1 1 1 2 2 2 0 Family of unknown function (DUF5337) Aminotran_3 PF00202.21 CRK17629.1 - 4.5e-76 256.1 0.0 1.5e-59 201.7 0.0 2.1 1 1 1 2 2 2 2 Aminotransferase class-III Zn_clus PF00172.18 CRK17629.1 - 9.1e-07 28.9 8.5 1.7e-06 28.0 8.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 CRK17629.1 - 2e-06 27.0 0.0 4.1e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 CRK17630.1 - 8.5e-24 84.1 64.7 1.1e-18 67.3 29.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF677 PF05055.12 CRK17630.1 - 0.14 11.0 0.2 0.27 10.1 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF677) Sarcoglycan_1 PF04790.13 CRK17633.1 - 8 5.7 6.2 1 8.7 0.1 2.0 2 0 0 2 2 2 0 Sarcoglycan complex subunit protein Acyltransf_C PF16076.5 CRK17635.1 - 4.3e-13 49.1 0.2 7e-13 48.5 0.2 1.3 1 0 0 1 1 1 1 Acyltransferase C-terminus Acyltransferase PF01553.21 CRK17635.1 - 0.005 16.5 0.0 0.0066 16.1 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase 5_nucleotid_C PF02872.18 CRK17636.1 - 7.3e-37 127.0 0.1 1.6e-36 125.9 0.1 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 CRK17636.1 - 4.2e-12 47.0 0.1 7.1e-12 46.3 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase YmdB PF13277.6 CRK17636.1 - 0.00012 21.5 0.0 0.00023 20.6 0.0 1.4 1 0 0 1 1 1 1 YmdB-like protein Git3 PF11710.8 CRK17638.1 - 2.8e-18 66.4 9.8 6.1e-18 65.3 9.8 1.6 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 CRK17638.1 - 5.5e-07 29.2 5.5 8.8e-07 28.5 5.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) GPR_Gpa2_C PF11970.8 CRK17638.1 - 0.00031 20.7 0.0 0.00069 19.6 0.0 1.6 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term Dicty_CAR PF05462.11 CRK17638.1 - 0.032 13.4 5.0 0.056 12.6 5.0 1.3 1 0 0 1 1 1 0 Slime mold cyclic AMP receptor Helitron_like_N PF14214.6 CRK17639.1 - 0.11 12.7 0.2 0.61 10.3 0.4 2.0 2 0 0 2 2 2 0 Helitron helicase-like domain at N-terminus Pec_lyase_C PF00544.19 CRK17640.1 - 8.2e-43 146.4 9.2 8.2e-43 146.4 9.2 1.5 2 0 0 2 2 2 1 Pectate lyase Beta_helix PF13229.6 CRK17640.1 - 0.023 14.5 21.0 0.15 11.9 16.7 2.5 1 1 1 2 2 2 0 Right handed beta helix region Acetyltransf_1 PF00583.25 CRK17641.1 - 6e-07 29.7 0.0 8.2e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CRK17641.1 - 2.6e-06 27.8 0.0 4.3e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CRK17641.1 - 6e-06 26.1 0.0 1.7e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 CRK17641.1 - 8.9e-06 25.7 0.0 1.9e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 CRK17641.1 - 0.008 16.9 0.0 0.013 16.2 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Asn_synthase PF00733.21 CRK17642.1 - 1.3e-20 74.4 0.0 1.6e-20 74.1 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 CRK17642.1 - 2.1e-05 24.4 0.0 3.3e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain NAD_synthase PF02540.17 CRK17642.1 - 0.00087 18.5 0.0 0.0012 18.0 0.0 1.2 1 0 0 1 1 1 1 NAD synthase QueC PF06508.13 CRK17642.1 - 0.0021 17.6 0.0 0.003 17.1 0.0 1.2 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 CRK17642.1 - 0.12 11.1 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase Med15_fungi PF05397.12 CRK17644.1 - 0.0092 16.2 0.0 0.0092 16.2 0.0 2.9 2 1 1 3 3 3 1 Mediator complex subunit 15 Atg8 PF02991.16 CRK17646.1 - 3.3e-32 110.8 0.5 4.4e-32 110.4 0.5 1.2 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Ribosom_S12_S23 PF00164.25 CRK17646.1 - 1.6e-20 72.8 0.4 2.3e-20 72.3 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein S12/S23 APG12 PF04110.13 CRK17646.1 - 0.001 19.4 0.1 0.0015 18.9 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 DUF5315 PF17242.2 CRK17647.1 - 1.2e-27 95.5 0.6 2.8e-27 94.3 0.6 1.6 1 0 0 1 1 1 1 Disordered region of unknown function (DUF5315) Coprogen_oxidas PF01218.18 CRK17648.1 - 1.1e-106 355.8 0.3 2e-106 355.1 0.3 1.3 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase SWIM PF04434.17 CRK17648.1 - 0.0051 16.5 3.0 0.65 9.7 0.0 2.4 2 0 0 2 2 2 2 SWIM zinc finger MitMem_reg PF13012.6 CRK17649.1 - 2.7e-37 127.6 0.0 3.5e-37 127.3 0.0 1.1 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function tRNA_bind_2 PF13725.6 CRK17649.1 - 0.0042 16.8 2.6 0.0056 16.4 2.6 1.2 1 0 0 1 1 1 1 Possible tRNA binding domain CBFD_NFYB_HMF PF00808.23 CRK17655.1 - 6.7e-15 55.1 0.7 9.5e-15 54.6 0.7 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Ribosomal_L38e PF01781.18 CRK17669.1 - 5.6e-32 109.7 4.7 6e-32 109.6 4.7 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family PHY PF00360.20 CRK17687.1 - 2.2e-24 85.8 0.0 4.5e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 Phytochrome region ApbA PF02558.16 CRK17687.1 - 1.4e-22 80.0 0.0 4e-22 78.5 0.0 1.7 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA HisKA PF00512.25 CRK17687.1 - 1.2e-07 31.7 0.3 3.8e-07 30.0 0.3 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain ApbA_C PF08546.11 CRK17687.1 - 0.01 16.0 0.0 0.028 14.6 0.0 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA C terminal Methylase_S PF01420.19 CRK17689.1 - 0.028 14.6 0.0 0.051 13.8 0.0 1.5 1 1 0 1 1 1 0 Type I restriction modification DNA specificity domain Spc110_C PF18520.1 CRK17689.1 - 0.046 13.3 2.1 0.24 11.0 0.2 2.7 2 1 0 2 2 2 0 Spindle pole body component 110 C-terminal domain V-SNARE_C PF12352.8 CRK17689.1 - 0.055 13.8 0.1 0.11 12.8 0.1 1.5 1 0 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus FMN_dh PF01070.18 CRK17693.1 - 7.2e-66 222.6 0.1 1.2e-65 221.9 0.1 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DEAD PF00270.29 CRK17693.1 - 6.1e-50 169.4 0.0 1.1e-48 165.3 0.0 2.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CRK17693.1 - 1.7e-26 92.8 0.0 4e-26 91.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Glu_synthase PF01645.17 CRK17693.1 - 8.5e-06 25.1 0.2 1.6e-05 24.2 0.2 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 CRK17693.1 - 9.1e-05 21.6 0.1 0.00024 20.3 0.0 1.6 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain ResIII PF04851.15 CRK17693.1 - 0.047 13.7 0.0 0.12 12.3 0.0 1.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit HSCB_C PF07743.13 CRK17694.1 - 8.6e-20 71.0 4.2 9.1e-20 70.9 1.5 2.0 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 CRK17694.1 - 1.4e-06 28.3 0.7 2.7e-06 27.4 0.7 1.4 1 0 0 1 1 1 1 DnaJ domain DJ-1_PfpI PF01965.24 CRK17695.1 - 8e-20 71.3 0.0 1.1e-19 70.8 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family GATase_3 PF07685.14 CRK17695.1 - 0.052 13.1 0.0 0.069 12.7 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 CRK17695.1 - 0.15 11.8 0.0 0.2 11.4 0.0 1.1 1 0 0 1 1 1 0 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.24 CRK17696.1 - 2.2e-13 50.3 0.0 3.2e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family GATase_3 PF07685.14 CRK17696.1 - 0.03 13.9 0.0 0.04 13.5 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 CRK17696.1 - 0.046 13.5 0.0 0.059 13.1 0.0 1.1 1 0 0 1 1 1 0 Glutamine amidotransferase class-I PCI PF01399.27 CRK17697.1 - 5.7e-12 46.1 0.0 1.7e-11 44.6 0.0 1.9 1 0 0 1 1 1 1 PCI domain Cor1 PF04803.12 CRK17697.1 - 0.089 13.0 0.7 2.8 8.2 0.3 2.3 2 0 0 2 2 2 0 Cor1/Xlr/Xmr conserved region RPN7 PF10602.9 CRK17697.1 - 0.12 12.0 1.4 0.37 10.5 1.4 1.8 1 1 0 1 1 1 0 26S proteasome subunit RPN7 Lipase_GDSL_2 PF13472.6 CRK17698.1 - 4.7e-20 72.7 0.0 6.6e-20 72.2 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 CRK17698.1 - 1.7e-08 34.7 0.0 3.1e-08 33.9 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase LRR_8 PF13855.6 CRK17699.1 - 0.05 13.4 1.5 1.2 9.0 0.2 3.0 3 0 0 3 3 3 0 Leucine rich repeat LRR_4 PF12799.7 CRK17699.1 - 0.091 13.2 0.7 22 5.6 0.1 3.7 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) Glyco_hydro_16 PF00722.21 CRK17700.1 - 1.2e-07 31.4 0.0 4.1e-06 26.4 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Hum_adeno_E3A PF05393.11 CRK17700.1 - 1.2 9.2 6.9 0.31 11.0 0.1 2.6 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein DUF3292 PF11696.8 CRK17701.1 - 1.8e-210 700.7 0.0 2.2e-210 700.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) Pex24p PF06398.11 CRK17701.1 - 0.0035 16.4 0.0 0.0054 15.8 0.0 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin CzcE PF16986.5 CRK17703.1 - 0.17 12.3 0.0 0.26 11.7 0.0 1.3 1 0 0 1 1 1 0 Heavy-metal resistance protein CzcE WD40 PF00400.32 CRK17704.1 - 2.6e-27 94.5 16.9 7.2e-06 26.7 0.9 7.2 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK17704.1 - 7.3e-07 29.4 0.2 0.55 10.6 0.0 5.3 5 1 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CRK17704.1 - 0.00014 20.7 8.5 0.23 10.1 0.1 5.5 4 2 2 6 6 6 3 Nucleoporin Nup120/160 F-box-like PF12937.7 CRK17704.1 - 0.0038 17.1 0.2 0.084 12.8 0.0 2.4 2 0 0 2 2 2 1 F-box-like Suppressor_APC PF11414.8 CRK17704.1 - 0.078 13.1 1.2 0.25 11.5 0.9 2.1 1 1 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein CM_2 PF01817.21 CRK17705.1 - 0.22 11.9 4.4 10 6.6 0.8 3.0 2 2 0 2 2 2 0 Chorismate mutase type II BCIP PF13862.6 CRK17706.1 - 2e-98 328.2 0.1 2.4e-69 233.3 0.0 2.2 2 0 0 2 2 2 2 p21-C-terminal region-binding protein DUF1499 PF07386.11 CRK17706.1 - 0.0032 18.0 0.1 8.3 7.0 0.0 3.5 2 2 0 2 2 2 2 Protein of unknown function (DUF1499) Peptidase_C14 PF00656.22 CRK17706.1 - 0.033 14.2 0.0 9.8 6.0 0.0 2.4 2 0 0 2 2 2 0 Caspase domain HEPN_Toprim_N PF18871.1 CRK17706.1 - 0.087 12.7 0.3 17 5.2 0.0 2.3 2 0 0 2 2 2 0 HEPN/Toprim N-terminal domain 1 MitMem_reg PF13012.6 CRK17709.1 - 4.9e-08 33.4 0.3 1.1e-07 32.3 0.3 1.6 1 1 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 CRK17709.1 - 1.4e-06 28.3 0.0 2.8e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease ADH_N PF08240.12 CRK17710.1 - 5.1e-51 171.1 8.8 4.7e-25 87.6 1.2 2.5 2 0 0 2 2 2 2 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 CRK17710.1 - 9.1e-12 44.9 4.0 0.0002 20.9 0.1 4.7 6 0 0 6 6 6 2 Glucose dehydrogenase C-terminus ADH_zinc_N PF00107.26 CRK17710.1 - 1.7e-07 31.2 4.9 0.0037 17.2 1.3 3.4 2 1 0 2 2 2 2 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 CRK17710.1 - 6.3e-07 28.9 7.7 0.0034 16.7 1.0 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 CRK17710.1 - 1.3e-06 28.1 3.6 0.017 14.7 0.3 2.3 2 0 0 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ThiF PF00899.21 CRK17710.1 - 3.9e-06 26.4 1.4 0.062 12.7 0.1 2.3 2 0 0 2 2 2 2 ThiF family Pyr_redox_2 PF07992.14 CRK17710.1 - 1.1e-05 24.9 0.5 0.12 11.6 0.1 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 CRK17710.1 - 3.2e-05 24.0 0.1 0.25 11.4 0.0 2.5 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase DAO PF01266.24 CRK17710.1 - 0.00026 20.7 5.1 0.2 11.2 0.6 2.6 2 0 0 2 2 2 2 FAD dependent oxidoreductase AdoHcyase_NAD PF00670.21 CRK17710.1 - 0.00029 20.9 4.9 0.22 11.6 0.5 2.3 2 0 0 2 2 2 2 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 3HCDH_N PF02737.18 CRK17710.1 - 0.00065 19.6 5.9 0.22 11.4 0.7 2.3 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 CRK17710.1 - 0.00066 20.2 4.3 0.21 12.2 0.3 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CRK17710.1 - 0.0011 19.2 10.5 0.18 12.0 0.7 3.6 4 0 0 4 4 4 2 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 CRK17710.1 - 0.0011 18.3 1.2 0.74 9.0 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_25 PF13649.6 CRK17710.1 - 0.0017 19.0 0.8 4 8.2 0.1 2.9 3 0 0 3 3 2 2 Methyltransferase domain ApbA PF02558.16 CRK17710.1 - 0.0019 17.9 0.4 1.7 8.3 0.1 2.3 2 0 0 2 2 2 2 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 CRK17710.1 - 0.0022 17.3 3.7 0.34 10.1 0.3 2.3 2 0 0 2 2 2 2 FAD binding domain 2-Hacid_dh_C PF02826.19 CRK17710.1 - 0.0023 17.3 1.4 1.6 8.1 0.1 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PCP_red PF08369.10 CRK17710.1 - 0.0037 17.4 0.4 3.5 7.9 0.0 2.4 2 0 0 2 2 2 2 Proto-chlorophyllide reductase 57 kD subunit HI0933_like PF03486.14 CRK17710.1 - 0.012 14.4 7.2 0.17 10.6 0.9 2.2 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_7 PF13241.6 CRK17710.1 - 0.022 15.2 0.2 13 6.3 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding HTH_31 PF13560.6 CRK17710.1 - 0.038 14.3 0.3 12 6.3 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain Methyltransf_16 PF10294.9 CRK17710.1 - 0.045 13.5 0.4 7.8 6.2 0.0 2.3 2 0 0 2 2 2 0 Lysine methyltransferase CBX7_C PF17218.3 CRK17710.1 - 0.047 13.4 0.0 16 5.3 0.0 2.5 2 0 0 2 2 2 0 CBX family C-terminal motif MTS PF05175.14 CRK17710.1 - 0.051 13.1 0.2 9.5 5.7 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase small domain SPATA48 PF15073.6 CRK17710.1 - 0.069 13.4 0.0 25 5.2 0.0 2.7 2 0 0 2 2 2 0 Spermatogenesis-associated protein 48 XdhC_C PF13478.6 CRK17710.1 - 0.074 13.6 0.2 18 5.8 0.0 2.6 2 0 0 2 2 2 0 XdhC Rossmann domain PuR_N PF09182.10 CRK17710.1 - 0.1 12.6 0.6 22 5.1 0.1 2.6 2 0 0 2 2 2 0 Bacterial purine repressor, N-terminal IL10 PF00726.17 CRK17710.1 - 0.1 12.1 0.0 61 3.1 0.0 3.1 3 0 0 3 3 3 0 Interleukin 10 FAD_binding_2 PF00890.24 CRK17710.1 - 0.15 11.1 7.1 1.4 7.9 0.8 2.2 2 0 0 2 2 2 0 FAD binding domain Sacchrp_dh_NADP PF03435.18 CRK17710.1 - 0.3 11.4 1.8 20 5.4 0.1 2.4 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain PPV_E2_C PF00511.17 CRK17710.1 - 0.78 10.0 4.7 23 5.3 0.4 2.8 2 0 0 2 2 2 0 E2 (early) protein, C terminal Trp_halogenase PF04820.14 CRK17710.1 - 1.7 7.4 7.0 3.6 6.3 0.8 2.2 2 0 0 2 2 2 0 Tryptophan halogenase NADH_4Fe-4S PF10589.9 CRK17710.1 - 5.7 7.1 7.1 25 5.0 0.4 2.9 3 0 0 3 3 2 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Vps5 PF09325.10 CRK17711.1 - 1.8e-10 40.8 0.2 2.9e-10 40.1 0.2 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 CRK17711.1 - 9e-08 32.1 0.0 1.9e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 PX domain Cupin_8 PF13621.6 CRK17712.1 - 2.8e-33 115.7 0.0 5.7e-33 114.7 0.0 1.4 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 CRK17712.1 - 1.2e-09 38.1 0.0 4.3e-07 29.7 0.0 2.3 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.22 CRK17712.1 - 0.00013 22.4 0.0 0.0013 19.1 0.0 2.2 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 CRK17712.1 - 0.061 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Cupin domain COPR5 PF15340.6 CRK17712.1 - 0.11 13.2 0.0 0.71 10.5 0.1 2.1 2 0 0 2 2 2 0 Cooperator of PRMT5 family DUF812 PF05667.11 CRK17713.1 - 0.0035 16.3 1.9 0.0035 16.3 1.9 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF812) IFT57 PF10498.9 CRK17713.1 - 0.04 12.9 3.5 0.086 11.8 3.5 1.5 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 BLOC1_2 PF10046.9 CRK17713.1 - 0.096 13.0 7.1 0.74 10.1 3.1 2.9 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GAS PF13851.6 CRK17713.1 - 0.16 11.3 13.3 0.18 11.1 8.1 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Herpes_UL6 PF01763.16 CRK17713.1 - 0.19 10.2 2.6 0.4 9.1 2.4 1.5 1 1 0 1 1 1 0 Herpesvirus UL6 like DUF2205 PF10224.9 CRK17713.1 - 0.39 10.8 3.1 0.66 10.0 0.9 2.3 2 0 0 2 2 2 0 Short coiled-coil protein KASH_CCD PF14662.6 CRK17713.1 - 0.95 9.3 12.6 1.1 9.1 5.0 2.9 3 0 0 3 3 3 0 Coiled-coil region of CCDC155 or KASH SOGA PF11365.8 CRK17713.1 - 2.6 9.2 12.9 0.33 12.1 3.6 3.1 3 0 0 3 3 3 0 Protein SOGA Spc24 PF08286.11 CRK17713.1 - 3.1 8.1 10.2 7.6 6.8 1.9 3.0 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 Nebulin PF00880.18 CRK17713.1 - 3.4 7.7 6.3 2.3 8.2 1.6 2.8 2 0 0 2 2 2 0 Nebulin repeat KxDL PF10241.9 CRK17713.1 - 4.5 7.6 14.6 2.4 8.5 2.4 3.4 3 0 0 3 3 3 0 Uncharacterized conserved protein DHR10 PF18595.1 CRK17713.1 - 7 6.7 26.1 0.2 11.7 10.0 3.3 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain Tropomyosin_1 PF12718.7 CRK17713.1 - 9.2 6.4 21.0 0.21 11.7 6.1 3.2 3 0 0 3 3 3 0 Tropomyosin like EamA PF00892.20 CRK17714.1 - 1.9e-05 24.8 17.7 0.0001 22.5 17.7 1.9 1 1 0 1 1 1 1 EamA-like transporter family TMEM234 PF10639.9 CRK17714.1 - 0.06 13.4 3.7 0.092 12.8 3.6 1.3 1 1 0 1 1 1 0 Putative transmembrane family 234 Voltage_CLC PF00654.20 CRK17715.1 - 2e-87 293.7 21.8 2.7e-87 293.3 21.8 1.1 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 CRK17715.1 - 4.9e-11 42.9 0.0 0.00014 22.2 0.0 2.5 2 0 0 2 2 2 2 CBS domain DEAD_assoc PF08494.11 CRK17715.1 - 0.13 12.1 0.0 0.38 10.5 0.0 1.7 2 0 0 2 2 2 0 DEAD/H associated Metallophos PF00149.28 CRK17716.1 - 0.00039 21.0 0.1 0.0014 19.1 0.1 1.8 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CRK17716.1 - 0.012 16.1 0.2 0.025 15.0 0.2 1.5 1 1 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain DUF3112 PF11309.8 CRK17717.1 - 6.7e-28 97.6 8.5 1.4e-26 93.3 0.4 2.8 3 1 0 3 3 3 1 Protein of unknown function (DUF3112) YvrJ PF12841.7 CRK17717.1 - 0.023 14.2 0.1 0.056 13.0 0.1 1.6 1 0 0 1 1 1 0 YvrJ protein family DUF2207 PF09972.9 CRK17717.1 - 0.17 10.6 0.1 1.3 7.6 0.1 2.1 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2897 PF11446.8 CRK17717.1 - 2.3 8.2 3.8 1.2 9.1 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2897) WD40 PF00400.32 CRK17718.1 - 0.004 18.0 8.6 0.65 11.0 0.1 4.7 4 0 0 4 4 4 2 WD domain, G-beta repeat LRR_9 PF14580.6 CRK17719.1 - 1.4e-29 102.8 0.3 4.1e-28 98.1 0.3 2.0 1 1 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 CRK17719.1 - 1.7e-06 28.2 0.2 7.7e-06 26.2 0.0 2.2 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CRK17719.1 - 3.4e-05 23.5 0.1 9.9e-05 22.0 0.0 1.9 2 0 0 2 2 2 1 Leucine rich repeat LRR_6 PF13516.6 CRK17719.1 - 0.43 10.7 2.5 6.1 7.2 0.0 3.0 4 0 0 4 4 4 0 Leucine Rich repeat Exo84_C PF16528.5 CRK17720.1 - 1.9e-75 253.2 1.0 1.9e-75 253.2 1.0 2.5 3 0 0 3 3 2 1 Exocyst component 84 C-terminal SNF2_N PF00176.23 CRK17720.1 - 1.4e-70 237.7 0.7 2.3e-70 237.1 0.7 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Radical_SAM PF04055.21 CRK17720.1 - 2.2e-25 89.9 0.1 6.5e-24 85.2 0.0 3.1 3 0 0 3 3 2 1 Radical SAM superfamily HIRAN PF08797.11 CRK17720.1 - 1.7e-16 60.0 0.0 3.9e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain Vps51 PF08700.11 CRK17720.1 - 3.3e-15 55.9 6.7 4e-15 55.7 4.2 2.6 2 0 0 2 2 2 1 Vps51/Vps67 Helicase_C PF00271.31 CRK17720.1 - 3.3e-12 46.7 0.0 1.1e-11 45.0 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Flavodoxin_1 PF00258.25 CRK17720.1 - 2.2e-10 40.9 0.0 8e-10 39.1 0.0 2.1 2 0 0 2 2 1 1 Flavodoxin SBP_bac_11 PF13531.6 CRK17720.1 - 3.2e-10 40.1 0.3 9.7e-10 38.6 0.3 1.8 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein zf-C3HC4_2 PF13923.6 CRK17720.1 - 4.2e-10 39.3 11.0 1.1e-09 38.0 11.0 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SBP_bac_6 PF13343.6 CRK17720.1 - 6.3e-10 38.9 0.1 1.5e-09 37.6 0.1 1.6 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 CRK17720.1 - 5.7e-09 36.2 1.2 1.9e-08 34.5 1.2 1.9 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein zf-C3HC4_3 PF13920.6 CRK17720.1 - 7.3e-09 35.4 8.8 7.3e-09 35.4 8.8 2.5 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) SBP_bac_1 PF01547.25 CRK17720.1 - 2.6e-08 34.2 5.2 4.4e-08 33.4 5.2 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein zf-RING_5 PF14634.6 CRK17720.1 - 1.2e-07 31.6 9.7 2.8e-07 30.4 9.7 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CRK17720.1 - 1.3e-07 31.4 10.7 1.3e-07 31.4 10.7 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CRK17720.1 - 1.6e-06 28.4 10.5 1.6e-06 28.4 10.5 2.3 3 0 0 3 3 1 1 Ring finger domain CBFD_NFYB_HMF PF00808.23 CRK17720.1 - 3.1e-06 27.4 0.1 1.1e-05 25.6 0.1 2.0 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone zf-C3HC4_4 PF15227.6 CRK17720.1 - 6.5e-06 26.2 9.6 1.5e-05 25.0 9.6 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 CRK17720.1 - 6.6e-06 26.1 11.3 1.9e-05 24.6 11.3 1.9 1 0 0 1 1 1 1 RING-type zinc-finger Wyosine_form PF08608.12 CRK17720.1 - 3.5e-05 24.1 0.0 9.2e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Wyosine base formation Prok-RING_4 PF14447.6 CRK17720.1 - 0.00028 20.7 7.7 0.00096 19.0 7.7 2.0 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 CRK17720.1 - 0.0025 18.1 8.6 0.0097 16.2 8.6 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_10 PF16685.5 CRK17720.1 - 0.0037 17.4 7.2 0.0092 16.1 7.2 1.6 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 CRK17720.1 - 0.0041 17.1 3.5 0.011 15.7 3.5 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger HMMR_C PF15908.5 CRK17720.1 - 0.03 14.6 6.0 3.4 7.9 2.0 3.0 2 1 0 2 2 2 0 Hyaluronan mediated motility receptor C-terminal zf-Nse PF11789.8 CRK17720.1 - 0.035 13.9 8.1 0.083 12.7 8.1 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Dor1 PF04124.12 CRK17720.1 - 0.38 9.4 12.6 0.71 8.5 2.2 2.5 2 0 0 2 2 2 0 Dor1-like family GldM_N PF12081.8 CRK17720.1 - 1.7 8.7 7.9 0.29 11.2 3.6 1.9 2 0 0 2 2 1 0 GldM N-terminal domain MFS_1 PF07690.16 CRK17722.1 - 1e-33 116.7 27.8 1.3e-33 116.4 27.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sigma70_r4 PF04545.16 CRK17722.1 - 0.21 11.1 0.2 0.39 10.3 0.2 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 CDO_I PF05995.12 CRK17723.1 - 4.3e-44 149.8 0.0 5.4e-44 149.5 0.0 1.2 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 CRK17723.1 - 0.055 12.9 0.2 0.09 12.2 0.2 1.5 1 1 0 1 1 1 0 PCO_ADO SLAC1 PF03595.17 CRK17724.1 - 2.8e-90 302.9 52.9 3.1e-90 302.7 52.9 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel MIP PF00230.20 CRK17725.1 - 2.3e-14 53.7 0.0 3.2e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Major intrinsic protein Dak1 PF02733.17 CRK17726.1 - 2.1e-82 276.5 2.7 3e-82 276.0 2.7 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 CRK17726.1 - 4.7e-28 98.2 0.0 9.8e-28 97.2 0.0 1.6 1 0 0 1 1 1 1 DAK2 domain Pkinase PF00069.25 CRK17727.1 - 1.1e-49 169.2 0.0 8.1e-49 166.3 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Cpn10 PF00166.21 CRK17727.1 - 5e-28 97.0 0.0 1e-27 96.0 0.0 1.6 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Pkinase_Tyr PF07714.17 CRK17727.1 - 1.4e-23 83.5 0.0 4.8e-23 81.8 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Chorion_2 PF03964.15 CRK17727.1 - 0.0098 16.7 0.6 0.024 15.5 0.6 1.6 1 0 0 1 1 1 1 Chorion family 2 APH PF01636.23 CRK17727.1 - 0.012 15.6 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CRK17727.1 - 0.036 13.0 0.0 0.057 12.4 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 CRK17727.1 - 0.1 11.9 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Kinase-like DUF2781 PF10914.8 CRK17727.1 - 0.11 12.9 0.0 0.17 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2781) SelP_N PF04592.14 CRK17727.1 - 3.6 6.9 9.7 5.8 6.2 9.7 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region LRR19-TM PF15176.6 CRK17728.1 - 0.042 13.9 0.0 0.049 13.6 0.0 1.1 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Ribosomal_L11 PF00298.19 CRK17729.1 - 1.8e-26 92.4 0.0 2.8e-26 91.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 CRK17729.1 - 1.8e-24 85.3 0.0 3.1e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Svf1 PF08622.10 CRK17730.1 - 2.2e-55 187.1 0.0 3.1e-55 186.7 0.0 1.2 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain Svf1_C PF17187.4 CRK17730.1 - 2e-45 154.6 1.3 1.2e-29 103.2 0.1 3.0 2 1 1 3 3 3 2 Svf1-like C-terminal lipocalin-like domain LPD18 PF18832.1 CRK17730.1 - 0.036 14.1 0.0 0.091 12.8 0.0 1.7 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 18 Acetyltransf_1 PF00583.25 CRK17731.1 - 0.0082 16.4 0.0 0.018 15.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FAR1 PF03101.15 CRK17732.1 - 4.9e-05 23.9 0.0 0.00014 22.5 0.0 1.7 1 0 0 1 1 1 1 FAR1 DNA-binding domain DHC_N2 PF08393.13 CRK17733.1 - 3.1e-169 563.3 24.7 1.5e-116 389.8 7.5 9.5 7 2 2 9 9 8 2 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.12 CRK17733.1 - 2.9e-143 478.5 6.8 3.6e-117 392.4 3.2 8.7 8 1 0 8 8 8 2 Dynein heavy chain, N-terminal region 1 AAA_8 PF12780.7 CRK17733.1 - 7e-131 435.2 0.0 5.4e-64 216.0 0.0 3.0 2 0 0 2 2 2 2 P-loop containing dynein motor region D4 AAA_7 PF12775.7 CRK17733.1 - 6.5e-80 266.9 0.0 6.2e-36 123.6 0.0 5.2 5 0 0 5 5 5 3 P-loop containing dynein motor region MT PF12777.7 CRK17733.1 - 1.5e-78 264.3 24.4 2.6e-40 138.5 8.3 3.0 2 0 0 2 2 2 2 Microtubule-binding stalk of dynein motor AAA_9 PF12781.7 CRK17733.1 - 4.6e-73 245.0 4.6 9e-73 244.0 1.2 3.6 3 0 0 3 3 1 1 ATP-binding dynein motor region Dynein_heavy PF03028.15 CRK17733.1 - 2.5e-61 205.0 0.0 9.6e-28 96.7 0.0 4.9 4 0 0 4 4 4 2 Dynein heavy chain region D6 P-loop domain AAA_lid_11 PF18198.1 CRK17733.1 - 6e-61 205.0 0.0 5.1e-29 101.2 0.0 2.6 2 0 0 2 2 2 2 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 CRK17733.1 - 9.4e-41 139.0 0.0 2.6e-11 43.7 0.0 8.3 7 0 0 7 7 7 5 AAA domain (dynein-related subfamily) DUF1774 PF08611.10 CRK17733.1 - 2.6e-33 114.2 1.6 6.4e-33 113.0 1.6 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1774) Dynein_AAA_lid PF17852.1 CRK17733.1 - 3.9e-32 111.0 0.0 1.8e-14 53.9 0.0 3.2 2 0 0 2 2 2 2 Dynein heavy chain AAA lid domain AAA PF00004.29 CRK17733.1 - 5.6e-22 78.6 0.0 0.0028 18.1 0.0 5.9 5 0 0 5 5 5 4 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CRK17733.1 - 6.5e-22 78.3 0.0 0.015 15.6 0.0 7.2 5 0 0 5 5 5 5 AAA domain AAA_18 PF13238.6 CRK17733.1 - 2.6e-14 53.9 4.1 0.13 12.8 0.0 7.4 7 0 0 7 7 5 4 AAA domain AAA_33 PF13671.6 CRK17733.1 - 5.6e-14 52.5 3.7 0.85 9.8 0.1 6.7 5 0 0 5 5 5 5 AAA domain AAA_6 PF12774.7 CRK17733.1 - 2.7e-13 49.6 0.1 1.3e-12 47.4 0.1 2.3 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region T2SSE PF00437.20 CRK17733.1 - 3.5e-11 42.7 0.0 0.028 13.5 0.0 4.8 5 0 0 5 5 5 2 Type II/IV secretion system protein AAA_25 PF13481.6 CRK17733.1 - 3e-08 33.5 0.0 0.44 10.1 0.0 5.3 4 0 0 4 4 4 2 AAA domain AAA_29 PF13555.6 CRK17733.1 - 4.5e-08 32.7 0.1 4.2 7.2 0.0 5.4 5 0 0 5 5 5 2 P-loop containing region of AAA domain AAA_19 PF13245.6 CRK17733.1 - 6e-08 33.1 0.1 0.51 10.7 0.0 5.2 5 0 0 5 5 4 2 AAA domain AAA_16 PF13191.6 CRK17733.1 - 6.7e-07 29.8 21.7 3.3 8.1 0.0 10.6 12 0 0 12 12 7 2 AAA ATPase domain Mg_chelatase PF01078.21 CRK17733.1 - 9.7e-07 28.4 4.7 1.2 8.5 0.0 5.3 5 0 0 5 5 5 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 CRK17733.1 - 1.9e-06 27.8 0.1 0.8 9.4 0.0 4.8 5 0 0 5 5 5 2 IstB-like ATP binding protein FAR1 PF03101.15 CRK17733.1 - 3.1e-05 24.6 0.0 0.00022 21.9 0.0 2.3 2 0 0 2 2 2 1 FAR1 DNA-binding domain AAA_lid_1 PF17857.1 CRK17733.1 - 3.5e-05 23.9 0.0 0.0012 19.1 0.0 3.5 3 0 0 3 3 3 1 AAA+ lid domain Rad17 PF03215.15 CRK17733.1 - 9.6e-05 22.4 0.0 12 5.8 0.0 5.2 5 0 0 5 5 5 0 Rad17 P-loop domain Kinase-PPPase PF03618.14 CRK17733.1 - 0.00012 22.0 0.0 0.97 9.2 0.0 3.0 2 0 0 2 2 2 2 Kinase/pyrophosphorylase FtsK_SpoIIIE PF01580.18 CRK17733.1 - 0.0004 19.8 5.7 4.4 6.6 0.0 5.9 7 0 0 7 7 5 0 FtsK/SpoIIIE family RuvB_N PF05496.12 CRK17733.1 - 0.00077 19.2 0.1 10 5.9 0.0 4.3 4 0 0 4 4 4 0 Holliday junction DNA helicase RuvB P-loop domain ABC_tran PF00005.27 CRK17733.1 - 0.0028 18.2 14.4 9.6 6.7 0.0 7.3 7 0 0 7 7 5 0 ABC transporter RNA_helicase PF00910.22 CRK17733.1 - 0.0099 16.3 0.1 33 4.9 0.0 5.4 6 0 0 6 6 5 0 RNA helicase DUF3755 PF12579.8 CRK17733.1 - 0.022 14.4 1.4 7.9 6.2 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3755) Vps23_core PF09454.10 CRK17733.1 - 0.029 14.3 8.3 31 4.6 0.4 5.0 4 0 0 4 4 4 0 Vps23 core domain CHAD PF05235.14 CRK17733.1 - 0.036 14.1 32.4 0.018 15.1 3.7 5.6 4 0 0 4 4 4 0 CHAD domain AAA_21 PF13304.6 CRK17733.1 - 0.04 13.7 0.7 20 4.9 0.0 3.7 5 0 0 5 5 2 0 AAA domain, putative AbiEii toxin, Type IV TA system NACHT PF05729.12 CRK17733.1 - 0.065 13.2 6.3 58 3.6 0.0 5.6 5 0 0 5 5 5 0 NACHT domain 3-alpha PF03475.14 CRK17733.1 - 0.12 12.3 0.9 25 4.9 0.1 3.0 2 0 0 2 2 2 0 3-alpha domain CW_7 PF08230.11 CRK17733.1 - 0.12 12.1 2.8 13 5.6 0.2 2.7 2 0 0 2 2 2 0 CW_7 repeat ALMT PF11744.8 CRK17733.1 - 1.9 7.2 20.1 6.7 5.4 6.1 3.4 2 0 0 2 2 2 0 Aluminium activated malate transporter KMP11 PF03037.16 CRK17733.1 - 5.8 7.8 9.1 19 6.2 0.1 4.0 4 0 0 4 4 2 0 Kinetoplastid membrane protein 11 PduV-EutP PF10662.9 CRK17733.1 - 6.3 6.5 8.8 21 4.9 0.1 4.1 6 0 0 6 6 3 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 CRK17733.1 - 6.8 6.2 8.0 97 2.5 0.0 4.6 5 0 0 5 5 5 0 CobW/HypB/UreG, nucleotide-binding domain Clr5 PF14420.6 CRK17734.1 - 6.8e-07 29.4 0.7 1.9e-06 28.0 0.1 2.1 2 0 0 2 2 2 1 Clr5 domain ABC_tran PF00005.27 CRK17735.1 - 2.9e-40 137.9 0.1 5.4e-19 69.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 CRK17735.1 - 2.2e-35 122.7 21.1 1.5e-20 74.0 9.9 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 CRK17735.1 - 7.5e-09 35.3 1.6 0.00016 21.2 0.5 3.3 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CRK17735.1 - 2.2e-08 34.8 0.4 0.00016 22.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 CRK17735.1 - 1.3e-07 31.3 2.3 0.013 15.2 0.1 3.3 3 0 0 3 3 3 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CRK17735.1 - 6.3e-07 29.4 0.1 0.0027 17.6 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 CRK17735.1 - 2.7e-06 27.9 0.2 0.022 15.1 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 CRK17735.1 - 4.5e-06 26.7 0.4 0.12 12.2 0.0 3.2 2 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 CRK17735.1 - 1.4e-05 25.4 0.0 0.28 11.5 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_25 PF13481.6 CRK17735.1 - 1.6e-05 24.6 0.0 0.085 12.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 CRK17735.1 - 9.3e-05 22.5 0.1 0.028 14.5 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase T2SSE PF00437.20 CRK17735.1 - 0.00017 20.7 0.2 0.037 13.1 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein NB-ARC PF00931.22 CRK17735.1 - 0.0002 20.6 0.4 0.39 9.8 0.1 2.8 2 1 0 2 2 2 2 NB-ARC domain NACHT PF05729.12 CRK17735.1 - 0.00022 21.2 0.1 0.4 10.6 0.0 2.7 2 0 0 2 2 2 2 NACHT domain DUF87 PF01935.17 CRK17735.1 - 0.00044 20.4 1.2 0.0032 17.6 0.1 2.2 2 0 0 2 2 2 1 Helicase HerA, central domain cobW PF02492.19 CRK17735.1 - 0.00045 19.9 1.3 0.14 11.7 0.3 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Pox_A32 PF04665.12 CRK17735.1 - 0.0016 18.0 0.9 0.3 10.5 0.1 2.3 2 0 0 2 2 2 1 Poxvirus A32 protein FtsK_SpoIIIE PF01580.18 CRK17735.1 - 0.002 17.5 0.0 0.12 11.7 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family Viral_helicase1 PF01443.18 CRK17735.1 - 0.002 17.9 0.0 1.2 8.8 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.12 CRK17735.1 - 0.0034 16.7 0.2 0.076 12.3 0.1 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_30 PF13604.6 CRK17735.1 - 0.0045 16.7 0.1 0.62 9.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 CRK17735.1 - 0.0049 16.9 0.1 2.8 8.0 0.1 2.4 2 0 0 2 2 2 1 Dynamin family AAA_33 PF13671.6 CRK17735.1 - 0.0051 17.0 0.1 3.4 7.8 0.0 3.0 3 0 0 3 3 2 1 AAA domain Septin PF00735.18 CRK17735.1 - 0.0096 15.2 0.1 4.1 6.6 0.0 2.2 2 0 0 2 2 2 1 Septin AAA_15 PF13175.6 CRK17735.1 - 0.0098 15.6 0.0 0.47 10.1 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 CRK17735.1 - 0.013 15.0 0.2 2 7.9 0.1 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region MobB PF03205.14 CRK17735.1 - 0.022 14.7 0.5 2.4 8.1 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF2075 PF09848.9 CRK17735.1 - 0.023 13.9 0.3 0.3 10.3 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.6 CRK17735.1 - 0.03 14.9 0.0 12 6.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 CRK17735.1 - 0.031 14.2 1.3 8.1 6.3 0.1 2.6 2 0 0 2 2 2 0 NTPase AAA PF00004.29 CRK17735.1 - 0.031 14.7 0.0 6.7 7.2 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 CRK17735.1 - 0.034 14.4 0.0 6.2 7.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 CRK17735.1 - 0.035 13.8 0.1 5.2 6.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 CRK17735.1 - 0.035 14.1 0.5 2 8.4 0.1 3.2 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Roc PF08477.13 CRK17735.1 - 0.043 14.0 0.4 14 6.0 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase CbiA PF01656.23 CRK17735.1 - 0.065 13.3 2.2 1.4 9.0 0.2 2.7 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_19 PF13245.6 CRK17735.1 - 0.068 13.5 0.0 1.3 9.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 CRK17735.1 - 0.069 12.9 0.1 15 5.2 0.0 2.8 3 0 0 3 3 3 0 IstB-like ATP binding protein GTP_EFTU PF00009.27 CRK17735.1 - 0.098 12.2 0.0 3.1 7.3 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain RNA_helicase PF00910.22 CRK17735.1 - 0.13 12.6 0.0 29 5.1 0.0 2.8 2 0 0 2 2 2 0 RNA helicase ACPS PF01648.20 CRK17735.1 - 0.15 12.2 0.0 0.34 11.1 0.0 1.6 1 0 0 1 1 1 0 4'-phosphopantetheinyl transferase superfamily TrwB_AAD_bind PF10412.9 CRK17735.1 - 0.15 10.9 0.9 9.5 5.0 0.0 3.2 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain AAA_10 PF12846.7 CRK17735.1 - 0.16 10.9 0.0 0.3 10.0 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain Zip PF02535.22 CRK17736.1 - 3.5e-56 190.8 5.6 1.3e-55 188.9 5.6 1.9 1 1 0 1 1 1 1 ZIP Zinc transporter Arrestin_N PF00339.29 CRK17737.1 - 0.00073 19.6 0.1 0.0027 17.8 0.0 2.0 3 0 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.12 CRK17737.1 - 0.0015 18.0 0.0 0.0031 17.0 0.0 1.6 1 0 0 1 1 1 1 Bul1 C terminus GatD_N PF18195.1 CRK17737.1 - 0.0086 15.4 0.1 5.5 6.4 0.0 2.4 2 0 0 2 2 2 2 GatD N-terminal domain Hamartin PF04388.12 CRK17738.1 - 6.2e-20 71.5 0.1 6.2e-20 71.5 0.1 4.2 3 1 1 4 4 4 2 Hamartin protein Glyco_hydro_17 PF00332.18 CRK17738.1 - 1.7e-07 31.2 0.2 3.6e-07 30.1 0.2 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 DJ-1_PfpI PF01965.24 CRK17739.1 - 2.5e-10 40.4 0.0 4.7e-10 39.5 0.0 1.5 2 0 0 2 2 2 1 DJ-1/PfpI family ThiJ_like PF17124.5 CRK17739.1 - 0.00069 19.4 0.0 0.0016 18.2 0.0 1.5 1 1 0 1 1 1 1 ThiJ/PfpI family-like Ribosomal_L23 PF00276.20 CRK17740.1 - 2.5e-11 43.8 0.0 4.3e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L23 End_N_terminal PF12218.8 CRK17740.1 - 0.19 11.5 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 N terminal extension of bacteriophage endosialidase Fungal_trans_2 PF11951.8 CRK17741.1 - 2.2e-32 112.4 2.9 7.2e-31 107.4 2.9 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK17741.1 - 0.14 12.3 15.1 0.37 11.0 15.1 1.7 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Mito_carr PF00153.27 CRK17742.1 - 6.7e-59 195.8 6.6 8.1e-22 77.0 0.1 4.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.19 CRK17742.1 - 0.4 11.1 2.6 4.5 7.7 0.4 3.3 2 1 1 3 3 3 0 Tim17/Tim22/Tim23/Pmp24 family MMR_HSR1 PF01926.23 CRK17743.1 - 1.1e-23 83.4 0.0 2.1e-23 82.6 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP1_OBG PF01018.22 CRK17743.1 - 1.4e-15 57.2 0.0 1.1e-06 28.4 0.0 2.6 3 0 0 3 3 3 2 GTP1/OBG FeoB_N PF02421.18 CRK17743.1 - 6.9e-08 32.2 0.0 2.6e-07 30.3 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B ABC_tran PF00005.27 CRK17743.1 - 0.019 15.5 0.0 0.039 14.5 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 CRK17743.1 - 0.066 13.6 0.5 9.7 6.5 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain Arf PF00025.21 CRK17743.1 - 0.1 12.0 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_18 PF13238.6 CRK17743.1 - 0.12 12.9 0.0 0.12 12.9 0.0 2.6 3 0 0 3 3 3 0 AAA domain PLDc_2 PF13091.6 CRK17746.1 - 1.1e-17 64.2 0.0 1.2e-06 28.4 0.0 3.6 3 1 0 3 3 3 3 PLD-like domain PLDc PF00614.22 CRK17746.1 - 3.5e-13 49.1 0.1 4.2e-05 23.5 0.0 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif Thioredoxin PF00085.20 CRK17747.1 - 1.7e-45 153.2 0.3 1.3e-24 86.1 0.0 3.9 3 1 0 3 3 3 3 Thioredoxin Thioredoxin_6 PF13848.6 CRK17747.1 - 3e-10 40.3 0.0 1.6e-05 24.9 0.0 4.1 2 1 2 4 4 4 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CRK17747.1 - 1.6e-07 31.6 0.4 0.025 14.9 0.0 4.8 3 2 2 5 5 5 1 Thioredoxin-like Thioredoxin_2 PF13098.6 CRK17747.1 - 3.4e-07 30.7 5.3 0.00031 21.2 0.1 4.2 3 2 0 3 3 3 2 Thioredoxin-like domain AhpC-TSA PF00578.21 CRK17747.1 - 0.00025 21.0 0.7 0.17 11.8 0.0 3.6 4 0 0 4 4 4 1 AhpC/TSA family Thioredoxin_7 PF13899.6 CRK17747.1 - 0.0038 17.4 0.6 0.049 13.8 0.0 2.9 3 0 0 3 3 3 1 Thioredoxin-like HyaE PF07449.11 CRK17747.1 - 0.005 16.8 0.0 11 6.1 0.0 3.7 4 0 0 4 4 4 1 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.6 CRK17747.1 - 0.035 14.2 0.0 1.3 9.1 0.0 2.9 3 0 0 3 3 3 0 Thioredoxin domain OST3_OST6 PF04756.13 CRK17747.1 - 0.072 12.4 0.0 8.5 5.6 0.0 2.6 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family Thioredoxin_5 PF13743.6 CRK17747.1 - 0.088 12.5 0.0 18 4.9 0.0 3.1 2 1 1 3 3 3 0 Thioredoxin TraF PF13728.6 CRK17747.1 - 0.27 11.0 0.0 0.27 11.0 0.0 3.6 3 1 1 4 4 4 0 F plasmid transfer operon protein Gram_pos_anchor PF00746.21 CRK17747.1 - 1.8 8.6 3.7 14 5.7 0.1 3.0 3 0 0 3 3 3 0 LPXTG cell wall anchor motif UBN_AB PF14075.6 CRK17747.1 - 1.9 8.2 6.3 0.081 12.6 0.5 1.6 2 0 0 2 2 2 0 Ubinuclein conserved middle domain Peptidase_S10 PF00450.22 CRK17748.1 - 3.3e-48 165.1 0.0 3.1e-44 152.0 0.0 2.2 1 1 0 1 1 1 1 Serine carboxypeptidase PagL PF09411.10 CRK17748.1 - 0.038 14.1 0.1 0.12 12.5 0.0 1.9 2 0 0 2 2 2 0 Lipid A 3-O-deacylase (PagL) Asp PF00026.23 CRK17750.1 - 7e-76 255.6 5.7 8.2e-76 255.4 5.7 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CRK17750.1 - 3.3e-12 47.0 2.3 2.6e-09 37.6 1.6 2.8 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 CRK17750.1 - 1.3e-05 25.7 0.8 0.053 14.2 0.2 3.1 2 1 0 2 2 2 2 Aspartyl protease Hce2 PF14856.6 CRK17751.1 - 2e-10 40.8 0.8 5.4e-10 39.5 0.2 1.9 2 0 0 2 2 2 1 Pathogen effector; putative necrosis-inducing factor Tyr-DNA_phospho PF06087.12 CRK17753.1 - 1.8e-162 541.1 0.0 2.1e-162 540.9 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.6 CRK17753.1 - 0.017 15.0 0.1 0.95 9.4 0.0 2.3 2 0 0 2 2 2 0 PLD-like domain PLDc PF00614.22 CRK17753.1 - 0.26 11.5 0.6 3.2 8.1 0.6 2.5 2 0 0 2 2 2 0 Phospholipase D Active site motif ACBP PF00887.19 CRK17754.1 - 7e-16 58.2 0.3 8.8e-16 57.9 0.3 1.1 1 0 0 1 1 1 1 Acyl CoA binding protein Pyr_redox_2 PF07992.14 CRK17755.1 - 9e-35 120.3 0.1 1.1e-34 120.0 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CRK17755.1 - 3.2e-10 40.4 0.3 1e-05 26.0 0.2 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CRK17755.1 - 0.00022 21.3 0.0 4.3 7.3 0.0 3.5 3 1 1 4 4 4 2 FAD-NAD(P)-binding DAO PF01266.24 CRK17755.1 - 0.0011 18.7 2.3 0.72 9.4 0.0 3.3 3 1 0 3 3 3 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 CRK17755.1 - 0.0014 17.8 0.1 0.0095 15.0 0.0 2.2 2 1 1 3 3 3 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 CRK17755.1 - 0.11 12.7 0.1 2.1 8.6 0.0 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 CRK17755.1 - 0.15 11.3 0.1 4.6 6.4 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.17 CRK17755.1 - 0.16 11.2 0.5 12 5.0 0.0 2.2 2 0 0 2 2 2 0 Thi4 family K_oxygenase PF13434.6 CRK17755.1 - 0.18 10.9 0.0 16 4.5 0.0 2.3 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) End3 PF12761.7 CRK17756.1 - 4.5e-77 258.7 4.0 6.1e-77 258.3 4.0 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.7 CRK17756.1 - 4e-46 155.2 0.0 1.3e-45 153.6 0.0 1.8 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 CRK17756.1 - 4.4e-07 29.0 0.3 9.6e-07 27.9 0.3 1.6 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 CRK17756.1 - 1.3e-05 25.5 0.0 5.6e-05 23.5 0.0 2.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 CRK17756.1 - 0.001 18.8 0.0 0.002 17.9 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 CRK17756.1 - 0.0013 18.5 0.3 0.0042 16.9 0.3 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 CRK17756.1 - 0.024 14.1 0.2 0.069 12.7 0.2 1.7 1 0 0 1 1 1 0 EF hand Med9 PF07544.13 CRK17756.1 - 0.034 14.2 1.2 0.034 14.2 1.2 2.2 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 COG2 PF06148.11 CRK17756.1 - 0.21 11.7 6.9 0.23 11.6 3.0 2.4 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 COG5 PF10392.9 CRK17756.1 - 0.7 10.1 3.2 2.4 8.3 1.7 2.1 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Laminin_II PF06009.12 CRK17756.1 - 1.1 9.3 4.6 2.1 8.4 0.2 2.2 1 1 1 2 2 2 0 Laminin Domain II MerR-DNA-bind PF09278.11 CRK17756.1 - 1.1 9.8 0.1 1.1 9.8 0.1 3.3 2 1 1 3 3 3 0 MerR, DNA binding CorA PF01544.18 CRK17756.1 - 3.2 7.0 6.0 5.2 6.3 6.0 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF4407 PF14362.6 CRK17756.1 - 4.5 6.5 5.8 7.2 5.9 5.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Angiomotin_C PF12240.8 CRK17756.1 - 5.3 6.5 11.7 3.6 7.1 4.1 2.7 2 1 1 3 3 3 0 Angiomotin C terminal UPF0242 PF06785.11 CRK17756.1 - 6.8 6.7 9.9 15 5.6 9.9 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Nsp1_C PF05064.13 CRK17756.1 - 8.3 6.3 9.4 15 5.4 6.0 2.7 1 1 0 2 2 2 0 Nsp1-like C-terminal region FlxA PF14282.6 CRK17756.1 - 9.2 6.3 7.9 17 5.5 0.2 2.4 1 1 1 2 2 2 0 FlxA-like protein DSPc PF00782.20 CRK17757.1 - 3.2e-10 39.9 0.0 1.3e-09 38.0 0.0 1.9 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 CRK17757.1 - 0.0066 16.7 0.0 0.011 16.1 0.0 1.3 1 0 0 1 1 1 1 Rit1 DUSP-like domain Y_phosphatase PF00102.27 CRK17757.1 - 0.14 11.7 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Peptidase_M28 PF04389.17 CRK17758.1 - 2.5e-28 99.1 0.0 3.7e-28 98.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 CRK17758.1 - 0.00013 21.7 0.1 0.00022 21.0 0.1 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Cutinase PF01083.22 CRK17759.1 - 5.8e-43 146.9 0.6 7.3e-43 146.6 0.6 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 CRK17759.1 - 0.00012 21.7 0.0 0.00025 20.7 0.0 1.5 1 0 0 1 1 1 1 PE-PPE domain DUF676 PF05057.14 CRK17759.1 - 0.0045 16.5 0.0 0.7 9.4 0.0 2.2 2 0 0 2 2 2 2 Putative serine esterase (DUF676) Palm_thioest PF02089.15 CRK17759.1 - 0.022 14.6 0.0 0.027 14.3 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase VirJ PF06057.11 CRK17759.1 - 0.034 14.0 0.0 0.05 13.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) DUF1295 PF06966.12 CRK17760.1 - 3.4e-14 52.9 0.0 4.6e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.17 CRK17760.1 - 6.4e-06 25.2 1.2 1.8e-05 23.7 1.2 1.7 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family AFG1_ATPase PF03969.16 CRK17761.1 - 3.1e-99 332.3 0.0 4.8e-95 318.5 0.0 2.4 2 1 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 CRK17761.1 - 0.00016 22.1 2.4 0.028 14.8 0.0 3.3 2 2 0 2 2 2 1 AAA ATPase domain Bac_DnaA PF00308.18 CRK17761.1 - 0.00018 21.4 0.7 0.42 10.4 0.1 2.7 2 1 0 2 2 2 2 Bacterial dnaA protein AAA_14 PF13173.6 CRK17761.1 - 0.0013 18.7 0.0 0.0028 17.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CRK17761.1 - 0.0023 18.2 0.1 0.03 14.6 0.0 2.8 3 1 0 3 3 3 1 AAA domain AAA PF00004.29 CRK17761.1 - 0.017 15.6 0.3 0.067 13.6 0.0 2.1 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CRK17761.1 - 0.028 14.4 0.0 0.057 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 CRK17761.1 - 0.039 14.0 0.0 0.074 13.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 CRK17761.1 - 0.075 13.6 0.1 5.8 7.4 0.0 2.6 2 1 1 3 3 3 0 ABC transporter TniB PF05621.11 CRK17761.1 - 0.12 11.8 0.0 1.3 8.4 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein NACHT PF05729.12 CRK17761.1 - 0.19 11.6 2.1 0.46 10.4 0.0 2.6 2 1 0 2 2 2 0 NACHT domain Cu_bind_like PF02298.17 CRK17762.1 - 0.00038 20.4 0.8 0.0016 18.4 0.8 1.9 1 1 0 1 1 1 1 Plastocyanin-like domain Copper-bind PF00127.20 CRK17762.1 - 0.0069 16.8 0.3 0.032 14.7 0.3 2.1 1 1 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family YjcB PF15940.5 CRK17762.1 - 0.065 13.4 0.1 0.14 12.4 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function Prok-RING_4 PF14447.6 CRK17763.1 - 5e-07 29.5 6.0 5e-07 29.5 6.0 2.2 2 2 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 CRK17763.1 - 2.7e-06 27.6 6.3 2.7e-06 27.6 6.3 2.9 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.6 CRK17763.1 - 3.2e-06 26.9 4.1 3.2e-06 26.9 4.1 2.8 2 2 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CRK17763.1 - 8.5e-05 22.4 4.4 8.5e-05 22.4 4.4 2.7 3 1 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CRK17763.1 - 0.00054 19.8 6.5 0.00054 19.8 6.5 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CRK17763.1 - 0.00092 19.0 4.2 0.00092 19.0 4.2 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CRK17763.1 - 0.044 14.1 5.9 0.044 14.1 5.9 2.6 3 0 0 3 3 3 0 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 CRK17763.1 - 0.054 13.7 4.5 0.054 13.7 4.5 2.4 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 CRK17763.1 - 0.063 13.3 3.7 0.063 13.3 3.7 2.5 1 1 1 2 2 2 0 RING-type zinc-finger Metallophos PF00149.28 CRK17765.1 - 1.8e-31 110.3 0.1 2.5e-22 80.4 0.0 2.1 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CRK17765.1 - 0.0015 19.0 0.1 0.0039 17.6 0.1 1.7 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain COA2 PF17051.5 CRK17766.1 - 0.00014 21.9 0.2 0.00021 21.3 0.2 1.5 1 1 0 1 1 1 1 Cytochrome C oxidase assembly factor 2 Med13_C PF06333.12 CRK17767.1 - 0.28 10.4 1.4 0.29 10.4 0.7 1.4 2 0 0 2 2 2 0 Mediator complex subunit 13 C-terminal domain PRCC PF10253.9 CRK17767.1 - 2.8 8.7 13.6 4.5 8.0 13.6 1.5 1 1 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Menin PF05053.13 CRK17767.1 - 4.4 5.5 13.8 5.9 5.1 13.8 1.2 1 0 0 1 1 1 0 Menin DNA_pol_phi PF04931.13 CRK17767.1 - 4.7 5.2 7.7 6.2 4.8 7.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 CRK17767.1 - 4.8 5.4 6.3 6.2 5.0 6.3 1.1 1 0 0 1 1 1 0 CDC45-like protein ABC_tran PF00005.27 CRK17768.1 - 2.6e-52 177.0 0.2 1.8e-30 106.2 0.1 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 CRK17768.1 - 3.3e-34 118.8 27.9 1.4e-20 74.1 9.6 3.1 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 CRK17768.1 - 8.7e-10 38.4 3.6 0.00073 19.0 0.4 4.2 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CRK17768.1 - 3.4e-08 34.2 0.4 0.00021 21.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 CRK17768.1 - 2.3e-07 30.4 2.3 0.016 14.9 0.1 3.1 3 0 0 3 3 3 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CRK17768.1 - 1.5e-06 28.2 0.1 0.0052 16.7 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 CRK17768.1 - 4.2e-06 26.8 0.7 0.24 11.2 0.1 3.9 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 CRK17768.1 - 1.9e-05 25.1 2.9 0.024 15.0 0.1 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 CRK17768.1 - 2.3e-05 24.1 0.0 0.11 12.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 CRK17768.1 - 4.4e-05 23.8 2.9 0.3 11.3 0.1 3.3 2 2 0 2 2 2 2 AAA domain NB-ARC PF00931.22 CRK17768.1 - 5.7e-05 22.4 0.5 0.51 9.5 0.1 3.6 3 1 0 3 3 3 2 NB-ARC domain MMR_HSR1 PF01926.23 CRK17768.1 - 0.00014 21.9 0.1 0.035 14.2 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase T2SSE PF00437.20 CRK17768.1 - 0.00024 20.3 0.1 0.049 12.7 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein NACHT PF05729.12 CRK17768.1 - 0.00027 20.9 0.1 0.49 10.3 0.0 2.8 2 0 0 2 2 2 2 NACHT domain SbcCD_C PF13558.6 CRK17768.1 - 0.00034 20.8 0.1 0.68 10.2 0.0 2.9 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF87 PF01935.17 CRK17768.1 - 0.00059 20.0 1.2 0.0038 17.3 0.1 2.3 2 0 0 2 2 2 1 Helicase HerA, central domain cobW PF02492.19 CRK17768.1 - 0.00072 19.2 1.4 0.17 11.4 0.3 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Pox_A32 PF04665.12 CRK17768.1 - 0.0021 17.5 0.9 0.36 10.2 0.1 2.4 2 0 0 2 2 2 1 Poxvirus A32 protein Viral_helicase1 PF01443.18 CRK17768.1 - 0.0024 17.6 0.0 1.6 8.5 0.0 2.7 3 0 0 3 3 2 1 Viral (Superfamily 1) RNA helicase FtsK_SpoIIIE PF01580.18 CRK17768.1 - 0.003 16.9 0.0 0.15 11.4 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family Zeta_toxin PF06414.12 CRK17768.1 - 0.005 16.1 0.3 0.092 12.0 0.1 2.3 2 0 0 2 2 2 1 Zeta toxin Dynamin_N PF00350.23 CRK17768.1 - 0.0061 16.6 0.1 3.4 7.7 0.1 2.5 2 0 0 2 2 2 1 Dynamin family AAA_30 PF13604.6 CRK17768.1 - 0.0072 16.1 0.3 0.82 9.4 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.7 CRK17768.1 - 0.0086 15.0 0.0 0.023 13.6 0.0 1.7 1 0 0 1 1 1 1 AAA-like domain AAA_33 PF13671.6 CRK17768.1 - 0.0096 16.1 0.1 6.2 7.0 0.0 3.0 3 0 0 3 3 2 0 AAA domain Septin PF00735.18 CRK17768.1 - 0.013 14.8 0.1 5.1 6.3 0.0 2.4 2 0 0 2 2 2 0 Septin AAA_15 PF13175.6 CRK17768.1 - 0.014 15.2 0.0 0.65 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_7 PF12775.7 CRK17768.1 - 0.022 14.3 0.2 2.4 7.6 0.1 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA PF00004.29 CRK17768.1 - 0.025 15.0 0.1 7.7 6.9 0.0 3.5 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 CRK17768.1 - 0.027 14.5 0.3 1.9 8.5 0.0 2.7 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF2075 PF09848.9 CRK17768.1 - 0.028 13.7 0.1 0.35 10.0 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) TrwB_AAD_bind PF10412.9 CRK17768.1 - 0.031 13.2 1.1 12 4.7 0.0 3.4 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain MobB PF03205.14 CRK17768.1 - 0.031 14.2 0.5 2.9 7.8 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.6 CRK17768.1 - 0.035 14.4 0.0 5.3 7.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 CRK17768.1 - 0.046 13.4 0.1 5.9 6.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 CRK17768.1 - 0.051 13.8 0.2 16 5.7 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 CRK17768.1 - 0.057 13.3 2.3 8.4 6.3 0.1 2.8 3 0 0 3 3 2 0 NTPase AAA_18 PF13238.6 CRK17768.1 - 0.061 13.9 0.0 21 5.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 CRK17768.1 - 0.093 12.5 0.1 18 5.0 0.0 2.9 3 0 0 3 3 2 0 IstB-like ATP binding protein AAA_5 PF07728.14 CRK17768.1 - 0.13 12.3 0.1 8.7 6.3 0.0 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 CRK17768.1 - 0.14 12.5 0.0 3.2 8.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 CRK17768.1 - 0.14 11.9 0.6 8.2 6.1 0.1 2.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Zip PF02535.22 CRK17769.1 - 8.1e-56 189.6 6.5 3e-55 187.8 6.5 1.8 1 1 0 1 1 1 1 ZIP Zinc transporter Bul1_C PF04426.12 CRK17770.1 - 0.00099 18.6 0.0 0.0019 17.7 0.0 1.5 1 0 0 1 1 1 1 Bul1 C terminus Hamartin PF04388.12 CRK17771.1 - 9.7e-23 80.7 0.0 9.7e-23 80.7 0.0 3.5 2 1 1 3 3 3 2 Hamartin protein Glyco_hydro_17 PF00332.18 CRK17771.1 - 1.4e-07 31.4 0.2 2.9e-07 30.4 0.2 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Ribosomal_L23 PF00276.20 CRK17773.1 - 7.9e-11 42.2 0.0 1.9e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L23 DJ-1_PfpI PF01965.24 CRK17773.1 - 7.7e-10 38.8 0.0 1.6e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 CRK17773.1 - 0.0019 17.9 0.0 0.0049 16.6 0.0 1.5 1 1 1 2 2 2 1 ThiJ/PfpI family-like Mito_carr PF00153.27 CRK17774.1 - 1.2e-31 108.5 4.8 1.7e-17 63.1 0.1 3.6 2 1 0 2 2 2 2 Mitochondrial carrier protein GTP1_OBG PF01018.22 CRK17775.1 - 1.2e-39 135.4 0.1 4e-30 104.5 0.5 2.4 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 CRK17775.1 - 1.7e-23 82.9 0.0 3.2e-23 82.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CRK17775.1 - 8.4e-08 31.9 0.0 3.2e-07 30.0 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 CRK17775.1 - 0.0023 16.9 0.1 0.55 9.2 0.0 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 CRK17775.1 - 0.024 15.2 0.0 0.048 14.2 0.0 1.6 1 0 0 1 1 1 0 ABC transporter GTP_EFTU PF00009.27 CRK17775.1 - 0.056 13.0 0.0 2.6 7.5 0.0 2.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Arf PF00025.21 CRK17775.1 - 0.089 12.2 0.0 0.23 10.9 0.0 1.6 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_18 PF13238.6 CRK17775.1 - 0.14 12.7 0.0 0.14 12.7 0.0 2.8 4 0 0 4 4 4 0 AAA domain PLDc_2 PF13091.6 CRK17777.1 - 1.2e-17 64.1 0.0 1.2e-06 28.4 0.0 3.6 3 1 0 3 3 3 3 PLD-like domain PLDc PF00614.22 CRK17777.1 - 3.7e-13 49.1 0.1 4.3e-05 23.5 0.0 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif Thioredoxin PF00085.20 CRK17778.1 - 1.9e-45 153.0 0.3 1.3e-24 86.1 0.0 4.0 3 1 0 3 3 3 3 Thioredoxin Thioredoxin_6 PF13848.6 CRK17778.1 - 2.3e-10 40.7 0.0 1.4e-05 25.1 0.0 4.3 3 1 2 5 5 5 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 CRK17778.1 - 1.5e-07 31.9 4.2 0.00031 21.1 0.1 4.0 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CRK17778.1 - 2.1e-07 31.1 0.3 0.025 14.9 0.0 4.6 3 2 2 5 5 5 1 Thioredoxin-like AhpC-TSA PF00578.21 CRK17778.1 - 0.00025 21.0 0.6 0.17 11.8 0.0 3.5 4 0 0 4 4 4 1 AhpC/TSA family Thioredoxin_7 PF13899.6 CRK17778.1 - 0.0039 17.3 0.6 0.049 13.8 0.0 2.9 3 0 0 3 3 3 1 Thioredoxin-like HyaE PF07449.11 CRK17778.1 - 0.004 17.1 0.0 11 6.1 0.0 3.7 4 0 0 4 4 4 1 Hydrogenase-1 expression protein HyaE OST3_OST6 PF04756.13 CRK17778.1 - 0.0069 15.8 0.0 3.3 7.0 0.0 2.7 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_3 PF13192.6 CRK17778.1 - 0.025 14.6 0.2 1.3 9.1 0.0 3.1 3 0 0 3 3 3 0 Thioredoxin domain UBN_AB PF14075.6 CRK17778.1 - 0.057 13.1 0.8 0.11 12.2 0.8 1.4 1 0 0 1 1 1 0 Ubinuclein conserved middle domain TraF PF13728.6 CRK17778.1 - 0.063 13.1 5.9 0.3 10.9 0.0 3.8 3 1 1 4 4 4 0 F plasmid transfer operon protein Thioredoxin_5 PF13743.6 CRK17778.1 - 0.09 12.4 0.0 18 4.9 0.0 3.1 2 1 1 3 3 3 0 Thioredoxin Repressor_Mnt PF11423.8 CRK17778.1 - 0.36 10.6 1.4 0.83 9.5 1.4 1.6 1 0 0 1 1 1 0 Regulatory protein Mnt DAO PF01266.24 CRK17779.1 - 2.6e-31 109.5 2.2 3.3e-31 109.1 2.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Peptidase_S10 PF00450.22 CRK17780.1 - 1.1e-97 328.2 0.1 1.3e-97 327.9 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Asp PF00026.23 CRK17781.1 - 4e-76 256.4 6.6 4.7e-76 256.2 6.6 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CRK17781.1 - 1.3e-12 48.3 3.0 1.3e-06 28.8 0.1 2.9 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 CRK17781.1 - 7.4e-06 26.5 1.0 0.027 15.1 0.3 3.1 2 1 0 2 2 2 2 Aspartyl protease Tyr-DNA_phospho PF06087.12 CRK17782.1 - 2.4e-158 527.5 0.0 2.8e-158 527.3 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.6 CRK17782.1 - 0.02 14.8 0.0 1.4 8.8 0.0 2.3 2 0 0 2 2 2 0 PLD-like domain ACBP PF00887.19 CRK17783.1 - 2.4e-11 43.7 0.2 2.8e-11 43.5 0.2 1.1 1 0 0 1 1 1 1 Acyl CoA binding protein Pyr_redox_2 PF07992.14 CRK17784.1 - 2.2e-35 122.3 0.1 2.8e-35 122.0 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CRK17784.1 - 1e-11 45.2 0.3 2.7e-07 31.0 0.2 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CRK17784.1 - 0.00021 21.3 0.0 4.6 7.2 0.0 3.7 3 1 1 4 4 4 2 FAD-NAD(P)-binding DAO PF01266.24 CRK17784.1 - 0.00056 19.6 2.9 1.1 8.8 0.0 3.9 3 1 1 4 4 4 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 CRK17784.1 - 0.0025 17.0 0.1 0.028 13.5 0.0 2.4 2 1 1 3 3 3 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 CRK17784.1 - 0.16 11.1 0.1 4.6 6.4 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.17 CRK17784.1 - 0.2 10.9 0.4 15 4.7 0.0 2.2 2 0 0 2 2 2 0 Thi4 family End3 PF12761.7 CRK17785.1 - 9.5e-77 257.7 3.6 1.3e-76 257.2 3.6 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.7 CRK17785.1 - 1.4e-46 156.7 0.0 1.3e-45 153.6 0.0 2.2 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 CRK17785.1 - 4.4e-07 29.0 0.3 9.6e-07 27.9 0.3 1.6 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 CRK17785.1 - 1.3e-05 25.6 0.0 5.6e-05 23.5 0.0 2.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 CRK17785.1 - 0.001 18.8 0.0 0.002 17.9 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 CRK17785.1 - 0.0013 18.5 0.3 0.0042 16.9 0.3 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 CRK17785.1 - 0.024 14.1 0.2 0.069 12.7 0.2 1.7 1 0 0 1 1 1 0 EF hand COG2 PF06148.11 CRK17785.1 - 0.19 11.8 6.3 0.23 11.6 2.4 2.4 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Med9 PF07544.13 CRK17785.1 - 0.76 9.9 6.2 0.11 12.6 0.8 2.3 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 MerR-DNA-bind PF09278.11 CRK17785.1 - 1 9.9 5.7 1.1 9.8 0.1 3.2 2 1 1 3 3 3 0 MerR, DNA binding CorA PF01544.18 CRK17785.1 - 4.5 6.5 5.7 8.1 5.7 5.7 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Nsp1_C PF05064.13 CRK17785.1 - 8.7 6.2 8.4 16 5.3 5.0 2.7 1 1 0 2 2 2 0 Nsp1-like C-terminal region UPF0242 PF06785.11 CRK17785.1 - 9.6 6.3 9.2 23 5.0 9.2 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DSPc PF00782.20 CRK17786.1 - 7.5e-10 38.7 0.0 2.1e-09 37.3 0.0 1.8 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 CRK17786.1 - 0.003 17.8 0.0 0.0047 17.2 0.0 1.3 1 0 0 1 1 1 1 Rit1 DUSP-like domain Peptidase_M28 PF04389.17 CRK17787.1 - 1.9e-28 99.5 0.0 3.1e-28 98.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 CRK17787.1 - 0.00011 22.0 0.1 0.00019 21.2 0.1 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 HAD PF12710.7 CRK17789.1 - 0.017 15.5 0.0 0.077 13.4 0.0 2.0 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CRK17789.1 - 0.073 13.3 0.0 0.2 11.9 0.0 1.7 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Cutinase PF01083.22 CRK17790.1 - 8.5e-44 149.6 1.1 1.1e-43 149.3 1.1 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 CRK17790.1 - 7.2e-06 25.7 0.1 1.6e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 PE-PPE domain Palm_thioest PF02089.15 CRK17790.1 - 0.0037 17.1 0.0 0.0044 16.9 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 CRK17790.1 - 0.023 14.2 0.0 0.13 11.7 0.0 1.9 2 0 0 2 2 2 0 Putative serine esterase (DUF676) VirJ PF06057.11 CRK17790.1 - 0.054 13.4 0.0 0.079 12.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Hydrolase_4 PF12146.8 CRK17790.1 - 0.057 12.7 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Lipase_3 PF01764.25 CRK17790.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) AFG1_ATPase PF03969.16 CRK17791.1 - 4.7e-99 331.7 0.0 4.2e-95 318.7 0.0 2.1 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 CRK17791.1 - 0.00013 22.3 0.2 0.039 14.3 0.1 2.9 2 1 0 2 2 2 1 AAA ATPase domain Bac_DnaA PF00308.18 CRK17791.1 - 0.00032 20.6 0.3 0.81 9.5 0.0 2.7 2 1 0 2 2 2 2 Bacterial dnaA protein AAA_14 PF13173.6 CRK17791.1 - 0.00093 19.2 0.0 0.0029 17.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain Cu_bind_like PF02298.17 CRK17791.1 - 0.0018 18.2 0.3 0.0051 16.8 0.3 1.7 1 1 0 1 1 1 1 Plastocyanin-like domain AAA_22 PF13401.6 CRK17791.1 - 0.0055 17.0 0.0 0.052 13.8 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 CRK17791.1 - 0.028 14.8 0.0 0.081 13.3 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Copper-bind PF00127.20 CRK17791.1 - 0.042 14.3 0.2 0.17 12.3 0.2 2.1 1 1 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family TsaE PF02367.17 CRK17791.1 - 0.043 13.8 0.0 0.093 12.7 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 CRK17791.1 - 0.048 13.7 0.0 0.089 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Prok-RING_4 PF14447.6 CRK17792.1 - 5.6e-07 29.3 6.2 5.6e-07 29.3 6.2 2.2 2 2 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 CRK17792.1 - 1.8e-06 28.2 6.5 1.8e-06 28.2 6.5 3.6 4 0 0 4 4 4 1 Ring finger domain zf-C3HC4_3 PF13920.6 CRK17792.1 - 3.3e-06 26.9 4.2 3.3e-06 26.9 4.2 2.8 2 2 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CRK17792.1 - 7.4e-05 22.6 4.6 7.4e-05 22.6 4.6 2.7 3 1 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CRK17792.1 - 0.00022 21.0 6.8 0.00022 21.0 6.8 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CRK17792.1 - 0.00037 20.3 4.6 0.00037 20.3 4.6 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CRK17792.1 - 0.023 14.9 6.0 0.023 14.9 6.0 3.4 4 0 0 4 4 4 0 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 CRK17792.1 - 0.033 14.4 5.0 0.033 14.4 5.0 2.4 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 CRK17792.1 - 0.042 13.9 3.9 0.042 13.9 3.9 2.5 1 1 1 2 2 2 0 RING-type zinc-finger zinc-ribbons_6 PF07191.12 CRK17792.1 - 3.6 7.6 10.9 2.2 8.3 3.1 2.2 2 0 0 2 2 2 0 zinc-ribbons Metallophos PF00149.28 CRK17793.1 - 1.7e-31 110.3 0.1 2.3e-22 80.5 0.0 2.1 1 1 0 2 2 2 2 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CRK17793.1 - 0.0014 19.0 0.1 0.0039 17.6 0.1 1.7 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain COA2 PF17051.5 CRK17794.1 - 0.00027 20.9 0.0 0.0007 19.6 0.0 1.7 2 0 0 2 2 2 1 Cytochrome C oxidase assembly factor 2 Cyclin_N PF00134.23 CRK17797.1 - 2.4e-06 27.3 0.0 7.4e-06 25.7 0.0 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain DUF5457 PF17540.2 CRK17797.1 - 0.24 11.5 0.1 0.4 10.8 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5457) PNP_phzG_C PF10590.9 CRK17798.1 - 7.2e-21 74.0 2.3 1.6e-20 72.9 1.5 2.1 2 0 0 2 2 2 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Putative_PNPOx PF01243.20 CRK17798.1 - 1.1e-17 64.0 0.1 2e-17 63.1 0.1 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.7 CRK17798.1 - 0.00021 21.9 0.0 0.00039 21.0 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase CPSase_L_D2 PF02786.17 CRK17799.1 - 2.7e-112 373.4 0.2 5.4e-83 277.6 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 CRK17799.1 - 2.4e-46 156.7 0.0 7.3e-46 155.2 0.0 1.9 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase small chain, CPSase domain OTCace_N PF02729.21 CRK17799.1 - 7.3e-46 155.9 0.0 1.6e-45 154.8 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain GATase PF00117.28 CRK17799.1 - 4.5e-45 153.7 0.0 9.1e-45 152.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.19 CRK17799.1 - 3.9e-39 133.8 0.0 1.2e-38 132.1 0.0 1.9 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 CRK17799.1 - 1.3e-30 106.6 0.0 3.7e-30 105.1 0.0 1.9 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 CRK17799.1 - 8.4e-22 77.2 0.0 3.7e-21 75.1 0.0 2.2 2 0 0 2 2 2 1 MGS-like domain Dala_Dala_lig_C PF07478.13 CRK17799.1 - 5.5e-17 62.0 1.0 1.7e-08 34.2 0.2 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 CRK17799.1 - 2.1e-14 53.5 0.1 1.2e-06 28.2 0.1 2.6 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 CRK17799.1 - 2.5e-10 40.2 0.0 2.3e-05 24.2 0.0 2.8 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Peptidase_C26 PF07722.13 CRK17799.1 - 1.7e-06 28.0 0.2 0.00023 21.0 0.2 2.6 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.14 CRK17799.1 - 3.7e-06 27.1 0.6 0.0098 15.9 0.1 2.8 2 0 0 2 2 2 2 ATP-grasp domain DJ-1_PfpI PF01965.24 CRK17799.1 - 4.2e-05 23.4 0.5 0.043 13.6 0.1 4.1 4 0 0 4 4 4 1 DJ-1/PfpI family TAP42 PF04177.12 CRK17803.1 - 2.9e-100 335.5 0.0 3.3e-100 335.3 0.0 1.0 1 0 0 1 1 1 1 TAP42-like family Ribonuclease_3 PF00636.26 CRK17804.1 - 2.6e-44 150.1 0.0 3.9e-22 78.8 0.1 2.8 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 CRK17804.1 - 3.1e-24 85.6 0.0 2.8e-09 37.2 0.0 3.7 3 0 0 3 3 3 3 Ribonuclease-III-like Dicer_dimer PF03368.14 CRK17804.1 - 4e-20 71.8 0.0 1.7e-17 63.4 0.0 3.0 2 0 0 2 2 2 1 Dicer dimerisation domain Helicase_C PF00271.31 CRK17804.1 - 4.4e-18 65.6 0.0 1.1e-17 64.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CRK17804.1 - 6e-14 52.4 0.1 1.7e-13 50.9 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CRK17804.1 - 1.7e-11 44.2 0.0 4.5e-11 42.8 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF2192 PF09958.9 CRK17804.1 - 0.0014 18.2 0.1 0.0028 17.2 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2192) AAA_22 PF13401.6 CRK17804.1 - 0.021 15.1 0.1 0.17 12.2 0.1 2.3 1 1 0 1 1 1 0 AAA domain PBP1_TM PF14812.6 CRK17804.1 - 0.62 10.5 4.7 1.5 9.3 4.7 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal 4HBT PF03061.22 CRK17805.1 - 1.1e-08 35.3 0.0 2.2e-08 34.3 0.0 1.5 1 1 0 1 1 1 1 Thioesterase superfamily MFS_1 PF07690.16 CRK17806.1 - 8e-25 87.5 30.6 1.2e-24 86.9 30.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily FAM176 PF14851.6 CRK17806.1 - 0.23 11.1 0.9 4 7.1 0.3 2.7 2 0 0 2 2 2 0 FAM176 family Sh_2 PF17512.2 CRK17807.1 - 0.0021 17.9 1.6 0.0035 17.1 1.6 1.3 1 0 0 1 1 1 1 Metapneumovirus Small hydrophobic protein PAN_1 PF00024.26 CRK17807.1 - 0.0054 16.7 0.0 0.017 15.1 0.0 1.8 1 0 0 1 1 1 1 PAN domain MTHFR PF02219.17 CRK17809.1 - 2.8e-112 374.7 0.0 4.6e-112 374.0 0.0 1.3 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase HTH_Tnp_Tc5 PF03221.16 CRK17809.1 - 1.8e-15 56.7 0.4 4.6e-06 26.6 0.0 5.5 4 1 0 4 4 4 3 Tc5 transposase DNA-binding domain DUF3425 PF11905.8 CRK17809.1 - 2.5e-13 50.1 0.0 7.5e-13 48.6 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) zf-C2H2_4 PF13894.6 CRK17809.1 - 0.0063 17.3 3.8 0.0063 17.3 3.8 4.4 5 0 0 5 5 5 1 C2H2-type zinc finger zf-C2H2 PF00096.26 CRK17809.1 - 0.017 15.5 18.6 0.079 13.4 3.9 4.7 3 1 0 3 3 3 0 Zinc finger, C2H2 type Homeobox_KN PF05920.11 CRK17809.1 - 0.75 9.7 5.9 0.097 12.6 1.2 2.0 2 0 0 2 2 2 0 Homeobox KN domain PWI PF01480.17 CRK17810.1 - 1.3e-05 25.4 0.3 4.8e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 PWI domain RRM_1 PF00076.22 CRK17810.1 - 0.0015 18.3 0.2 0.064 13.1 0.0 2.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FTA4 PF13093.6 CRK17810.1 - 0.07 13.0 2.7 0.28 11.1 1.4 2.3 2 0 0 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 UPF0184 PF03670.13 CRK17810.1 - 0.42 11.0 2.5 1.3 9.5 2.5 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) Solute_trans_a PF03619.16 CRK17811.1 - 7.3e-85 284.7 4.8 8.1e-85 284.5 4.3 1.3 1 1 0 1 1 1 1 Organic solute transporter Ostalpha Glyco_hydro_92 PF07971.12 CRK17812.1 - 2.4e-139 465.2 0.1 3e-139 464.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 CRK17812.1 - 2.9e-50 171.4 2.8 4.4e-50 170.8 2.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Gram_pos_anchor PF00746.21 CRK17812.1 - 1.2 9.2 3.8 17 5.4 0.6 2.6 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Spt4 PF06093.13 CRK17813.1 - 0.017 15.2 0.2 3.9 7.6 0.4 3.5 4 0 0 4 4 4 0 Spt4/RpoE2 zinc finger DUF2285 PF10074.9 CRK17813.1 - 0.13 12.9 1.4 0.53 11.0 1.4 2.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2285) Zn_clus PF00172.18 CRK17813.1 - 0.15 12.2 6.7 0.37 11.0 6.7 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain IPP-2 PF04979.14 CRK17813.1 - 2.7 8.7 7.0 0.21 12.4 1.4 2.0 2 0 0 2 2 2 0 Protein phosphatase inhibitor 2 (IPP-2) Sec5 PF15469.6 CRK17814.1 - 1.2e-20 74.1 0.0 4.8e-20 72.2 0.0 2.0 2 1 0 2 2 2 1 Exocyst complex component Sec5 Sec15 PF04091.12 CRK17814.1 - 0.00026 20.5 0.1 0.00052 19.5 0.1 1.4 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like Vps51 PF08700.11 CRK17814.1 - 0.00031 20.8 2.2 0.00074 19.6 0.1 2.6 2 1 0 2 2 2 1 Vps51/Vps67 RINT1_TIP1 PF04437.13 CRK17814.1 - 0.018 13.9 0.3 0.029 13.3 0.3 1.3 1 0 0 1 1 1 0 RINT-1 / TIP-1 family DUF2451 PF10474.9 CRK17814.1 - 0.02 14.7 0.3 0.16 11.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function C-terminus (DUF2451) Iso_dh PF00180.20 CRK17815.1 - 3.9e-61 207.1 0.0 3.3e-59 200.8 0.0 2.0 1 1 1 2 2 2 2 Isocitrate/isopropylmalate dehydrogenase Phage_30_3 PF08010.11 CRK17815.1 - 0.044 13.6 0.0 0.082 12.7 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage protein GP30.3 BSP PF04450.12 CRK17817.1 - 4.6e-77 258.5 0.0 5.7e-77 258.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase of plants and bacteria CLASP_N PF12348.8 CRK17818.1 - 1.3e-131 437.1 0.1 1.4e-87 293.0 0.0 2.5 2 0 0 2 2 2 2 CLASP N terminal HEAT PF02985.22 CRK17818.1 - 1.9e-05 24.5 0.7 9.3 6.8 0.0 5.6 6 0 0 6 6 6 1 HEAT repeat Cnd1 PF12717.7 CRK17818.1 - 0.00016 21.8 0.0 0.026 14.6 0.0 2.7 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 CRK17818.1 - 0.035 14.7 0.0 12 6.6 0.0 3.1 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region YozD PF14162.6 CRK17818.1 - 0.11 12.8 0.1 14 6.0 0.0 2.7 3 0 0 3 3 3 0 YozD-like protein Adaptin_N PF01602.20 CRK17818.1 - 0.21 10.1 0.0 0.76 8.3 0.0 2.0 2 0 0 2 2 2 0 Adaptin N terminal region HlyIII PF03006.20 CRK17819.1 - 2.9e-41 141.6 15.9 2.6e-36 125.5 10.7 2.1 1 1 1 2 2 2 2 Haemolysin-III related ATPase_gene1 PF09527.10 CRK17819.1 - 0.11 12.7 3.9 0.64 10.2 2.6 2.4 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter SirB PF04247.12 CRK17819.1 - 1.8 8.7 6.8 2 8.5 0.7 2.6 2 1 1 3 3 3 0 Invasion gene expression up-regulator, SirB RhoGAP PF00620.27 CRK17821.1 - 2.8e-45 153.9 0.0 2.8e-45 153.9 0.0 2.9 3 1 1 4 4 4 1 RhoGAP domain LIM PF00412.22 CRK17821.1 - 3.1e-12 46.5 12.9 6.6e-07 29.5 0.2 2.4 2 0 0 2 2 2 2 LIM domain IFT20 PF14931.6 CRK17821.1 - 0.0042 17.3 2.3 0.0042 17.3 2.3 2.4 2 0 0 2 2 2 1 Intraflagellar transport complex B, subunit 20 Zn-ribbon_8 PF09723.10 CRK17821.1 - 0.45 10.7 14.8 1.1 9.4 1.2 3.5 3 0 0 3 3 3 0 Zinc ribbon domain zf-ribbon_3 PF13248.6 CRK17821.1 - 1.4 8.4 12.6 0.8 9.2 0.0 3.6 3 1 0 3 3 3 0 zinc-ribbon domain GIT_CC PF16559.5 CRK17821.1 - 1.5 8.8 5.2 18 5.3 0.1 3.3 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Laminin_II PF06009.12 CRK17821.1 - 6.5 6.8 9.9 0.55 10.2 1.6 2.4 2 0 0 2 2 2 0 Laminin Domain II DUF4407 PF14362.6 CRK17822.1 - 4.1 6.7 8.6 7.8 5.7 8.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4210 PF13915.6 CRK17823.1 - 6.4e-33 113.2 0.1 1.6e-32 111.9 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.6 CRK17823.1 - 1.6e-24 85.8 1.0 2.7e-24 85.1 0.2 1.9 2 0 0 2 2 2 1 Chromosome segregation during meiosis PPR_2 PF13041.6 CRK17824.1 - 1e-18 67.3 5.7 4.9e-06 26.6 0.0 7.3 7 1 1 8 8 8 3 PPR repeat family PPR PF01535.20 CRK17824.1 - 1.3e-10 40.8 2.4 0.024 14.8 0.0 7.9 8 0 0 8 8 8 1 PPR repeat PPR_3 PF13812.6 CRK17824.1 - 7.6e-10 38.7 0.0 0.00083 19.4 0.0 5.1 5 2 2 7 7 6 3 Pentatricopeptide repeat domain PPR_1 PF12854.7 CRK17824.1 - 1.4e-07 31.1 0.0 0.001 18.7 0.0 5.3 6 0 0 6 6 6 1 PPR repeat TPR_14 PF13428.6 CRK17824.1 - 0.00055 20.5 7.8 1.1 10.3 0.0 6.5 10 0 0 10 10 6 2 Tetratricopeptide repeat PPR_long PF17177.4 CRK17824.1 - 0.0011 18.4 0.0 17 4.7 0.0 4.3 4 0 0 4 4 4 0 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 CRK17824.1 - 0.0034 17.9 0.1 79 3.9 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 CRK17824.1 - 0.0059 16.6 0.6 24 5.2 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 CRK17824.1 - 0.03 15.0 1.2 14 6.4 0.2 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 CRK17824.1 - 0.1 12.9 3.9 2.2 8.6 0.2 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 CRK17824.1 - 0.98 9.7 9.6 22 5.5 0.3 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 CRK17824.1 - 3.4 8.5 4.8 31 5.5 0.0 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat SRP68 PF16969.5 CRK17825.1 - 3.9e-174 580.8 14.2 4.3e-174 580.6 14.2 1.0 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 DUF5053 PF16476.5 CRK17825.1 - 0.0015 18.2 0.0 0.0035 17.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5053) Mis14 PF08641.12 CRK17825.1 - 0.12 12.7 2.4 0.2 12.0 0.2 2.4 2 0 0 2 2 2 0 Kinetochore protein Mis14 like HSP70 PF00012.20 CRK17826.1 - 6.7e-132 440.7 9.1 7.6e-132 440.5 9.1 1.0 1 0 0 1 1 1 1 Hsp70 protein FGGY_C PF02782.16 CRK17826.1 - 0.00054 19.7 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain UVR PF02151.19 CRK17826.1 - 0.013 15.2 6.1 0.051 13.3 6.1 2.1 1 0 0 1 1 1 0 UvrB/uvrC motif PPL5 PF18168.1 CRK17826.1 - 0.44 9.8 3.9 0.69 9.2 3.9 1.2 1 0 0 1 1 1 0 Prim-pol family 5 LTXXQ PF07813.12 CRK17826.1 - 9.9 6.9 7.4 1.4 9.7 1.1 2.6 2 2 1 3 3 3 0 LTXXQ motif family protein SRP68 PF16969.5 CRK17828.1 - 2e-34 119.5 0.2 2.3e-34 119.3 0.2 1.0 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 DUF755 PF05501.11 CRK17828.1 - 0.19 12.0 0.0 0.28 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Stb3 PF10330.9 CRK17862.1 - 9.3e-22 76.9 0.1 1.7e-21 76.0 0.1 1.4 1 0 0 1 1 1 1 Putative Sin3 binding protein zf-C2H2 PF00096.26 CRK17862.1 - 9.1e-08 32.1 19.1 8.4e-06 26.0 3.7 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CRK17862.1 - 1.2e-05 25.8 13.0 2.1e-05 25.0 2.5 3.6 3 0 0 3 3 3 1 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CRK17862.1 - 3.3e-05 24.1 4.2 3.3e-05 24.1 4.2 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_8 PF15909.5 CRK17862.1 - 0.00011 22.4 4.3 0.00028 21.1 4.3 1.6 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 CRK17862.1 - 0.00031 20.9 1.1 0.00031 20.9 1.1 2.4 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding SF1-HH PF16275.5 CRK17862.1 - 0.0039 17.5 0.1 0.013 15.8 0.0 1.8 2 0 0 2 2 2 1 Splicing factor 1 helix-hairpin domain zf-C2H2_6 PF13912.6 CRK17862.1 - 0.014 15.3 2.3 0.014 15.3 2.3 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-TRAF PF02176.18 CRK17862.1 - 0.025 15.2 2.7 0.025 15.2 2.7 2.3 2 0 0 2 2 2 0 TRAF-type zinc finger zf-met PF12874.7 CRK17862.1 - 0.067 13.6 0.8 0.067 13.6 0.8 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 CRK17862.1 - 0.088 12.7 1.8 0.28 11.1 1.8 1.9 1 0 0 1 1 1 0 zinc-finger of a C2HC-type FOXP-CC PF16159.5 CRK17862.1 - 0.11 13.1 7.8 0.77 10.4 0.4 3.1 1 1 2 3 3 3 0 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 CRK17862.1 - 0.35 11.0 5.0 1 9.5 5.0 1.7 1 1 0 1 1 1 0 Aberrant zinc-finger E7R PF17467.2 CRK17862.1 - 0.44 10.7 2.7 7.2 6.9 0.3 2.7 3 0 0 3 3 3 0 Viral Protein E7 zf-C2H2_2 PF12756.7 CRK17862.1 - 0.51 10.7 5.0 1.3 9.4 4.1 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2HE PF16278.5 CRK17862.1 - 4.7 7.7 8.2 7.7 7.1 7.1 2.1 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf-H2C2_5 PF13909.6 CRK17862.1 - 5.4 6.9 8.9 0.73 9.6 2.3 2.9 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Topoisom_bac PF01131.20 CRK17863.1 - 2e-66 224.7 0.2 3.1e-60 204.3 0.0 2.1 2 0 0 2 2 2 2 DNA topoisomerase Toprim PF01751.22 CRK17863.1 - 4.8e-18 65.3 0.0 1.1e-17 64.2 0.0 1.6 1 0 0 1 1 1 1 Toprim domain FoP_duplication PF13865.6 CRK17863.1 - 4.5 7.9 13.7 12 6.5 13.7 1.7 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 DUF1295 PF06966.12 CRK17864.1 - 9.5e-35 120.2 9.8 1.2e-34 119.9 9.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 CRK17864.1 - 0.055 13.9 2.7 6.9 7.2 0.0 2.7 3 0 0 3 3 3 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF4149 PF13664.6 CRK17865.1 - 6.7e-24 84.2 4.2 1.1e-23 83.5 3.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) DUF1772 PF08592.11 CRK17865.1 - 0.0014 18.9 0.1 0.0022 18.3 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) DUF5510 PF17629.2 CRK17865.1 - 0.24 11.3 1.5 0.37 10.7 0.2 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5510) Pectate_lyase PF03211.13 CRK17866.1 - 4.6e-64 215.7 2.2 5.6e-64 215.4 2.2 1.1 1 0 0 1 1 1 1 Pectate lyase Ku_PK_bind PF08785.11 CRK17867.1 - 1.2e-36 125.5 0.0 2.9e-36 124.3 0.0 1.7 1 0 0 1 1 1 1 Ku C terminal domain like Ku PF02735.16 CRK17867.1 - 6.6e-30 104.3 0.0 1.5e-29 103.2 0.0 1.6 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 CRK17867.1 - 2.3e-12 47.2 0.0 3.6e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain VWA PF00092.28 CRK17867.1 - 8.6e-05 22.9 0.0 0.00015 22.1 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Prok-E2_A PF14457.6 CRK17867.1 - 0.087 12.4 0.0 0.23 11.1 0.0 1.7 2 0 0 2 2 2 0 Prokaryotic E2 family A DnaJ PF00226.31 CRK17868.1 - 0.00021 21.3 0.0 0.00046 20.3 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 CRK17868.1 - 0.035 14.1 0.0 0.52 10.3 0.0 2.3 2 0 0 2 2 2 0 Pam16 Gemin7 PF11095.8 CRK17868.1 - 0.15 12.0 0.0 0.67 9.9 0.0 2.1 2 0 0 2 2 2 0 Gem-associated protein 7 (Gemin7) Ribosomal_L24e PF01246.20 CRK17869.1 - 1.1e-29 102.5 6.4 2.5e-29 101.3 6.4 1.6 1 0 0 1 1 1 1 Ribosomal protein L24e DUF5078 PF16877.5 CRK17869.1 - 0.052 14.0 0.3 0.09 13.2 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5078) DUF3602 PF12223.8 CRK17870.1 - 2.2e-13 50.6 12.8 0.00017 22.1 1.8 3.2 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) HABP4_PAI-RBP1 PF04774.15 CRK17870.1 - 0.33 11.8 13.3 0.48 11.3 4.3 2.5 1 1 2 3 3 3 0 Hyaluronan / mRNA binding family zf-C2H2 PF00096.26 CRK17872.1 - 0.041 14.3 3.3 0.041 14.3 3.3 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-BED PF02892.15 CRK17872.1 - 6 7.0 6.9 0.85 9.7 2.0 2.1 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_4 PF13894.6 CRK17872.1 - 7.8 7.6 6.4 6.8 7.8 3.9 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger PHD PF00628.29 CRK17876.1 - 7.4e-06 25.8 5.3 1.3e-05 25.0 5.3 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 CRK17876.1 - 0.008 16.4 1.5 0.016 15.4 1.5 1.5 1 0 0 1 1 1 1 PHD-like zinc-binding domain ING PF12998.7 CRK17876.1 - 0.0099 16.5 0.0 0.024 15.2 0.0 1.7 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding RXT2_N PF08595.11 CRK17876.1 - 0.043 13.8 0.2 0.043 13.8 0.2 2.8 3 0 0 3 3 3 0 RXT2-like, N-terminal zf-HC5HC2H_2 PF13832.6 CRK17876.1 - 0.1 12.8 1.2 0.22 11.7 1.2 1.5 1 0 0 1 1 1 0 PHD-zinc-finger like domain PHD_2 PF13831.6 CRK17876.1 - 0.27 10.8 1.5 0.45 10.1 1.5 1.4 1 0 0 1 1 1 0 PHD-finger Sialidase PF02973.16 CRK17877.1 - 0.045 13.2 0.0 0.056 12.9 0.0 1.1 1 0 0 1 1 1 0 Sialidase, N-terminal domain PHD PF00628.29 CRK17878.1 - 8.6e-07 28.8 5.3 1.3e-06 28.1 5.3 1.3 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 CRK17878.1 - 0.00094 19.4 1.9 0.0019 18.4 1.9 1.5 1 1 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 CRK17878.1 - 0.013 15.7 1.3 0.019 15.1 1.3 1.3 1 0 0 1 1 1 0 PHD-zinc-finger like domain PHD_2 PF13831.6 CRK17878.1 - 0.028 14.0 1.5 0.055 13.0 1.5 1.5 1 0 0 1 1 1 0 PHD-finger Amido_AtzD_TrzD PF09663.10 CRK17879.1 - 0.014 14.4 0.3 0.018 14.1 0.3 1.1 1 0 0 1 1 1 0 Amidohydrolase ring-opening protein (Amido_AtzD_TrzD) MA3 PF02847.17 CRK17881.1 - 5e-22 78.0 0.0 1.1e-21 76.9 0.0 1.6 1 0 0 1 1 1 1 MA3 domain TFIIA PF03153.13 CRK17881.1 - 0.0045 17.0 4.3 0.0045 17.0 4.3 3.9 4 0 0 4 4 4 1 Transcription factor IIA, alpha/beta subunit LRR19-TM PF15176.6 CRK17881.1 - 0.01 15.8 2.1 5.9 7.0 0.2 3.1 2 0 0 2 2 2 2 Leucine-rich repeat family 19 TM domain SUIM_assoc PF16619.5 CRK17881.1 - 0.36 10.9 19.5 0.58 10.3 8.5 3.2 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 ANAPC_CDC26 PF10471.9 CRK17881.1 - 0.86 10.5 24.5 0.54 11.1 8.3 3.5 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 DUF2722 PF10846.8 CRK17881.1 - 2.3 7.1 24.8 0.015 14.3 4.5 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2722) Band_7 PF01145.25 CRK17881.1 - 2.3 8.2 13.8 6.8 6.7 4.9 2.7 2 0 0 2 2 2 0 SPFH domain / Band 7 family DUF3371 PF11851.8 CRK17881.1 - 2.4 9.3 12.1 8.5 7.5 4.8 3.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) RPN2_C PF18004.1 CRK17881.1 - 7.6 6.4 14.0 4.8 7.1 1.9 3.5 3 0 0 3 3 3 0 26S proteasome regulatory subunit RPN2 C-terminal domain Hydin_ADK PF17213.3 CRK17881.1 - 7.7 6.7 7.9 7.6 6.8 0.8 3.7 4 0 0 4 4 4 0 Hydin Adenylate kinase-like domain DPM2 PF07297.12 CRK17882.1 - 5.5e-32 109.9 1.8 7.1e-32 109.6 1.8 1.1 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 CRK17882.1 - 0.00032 20.6 0.7 0.00055 19.8 0.7 1.4 1 0 0 1 1 1 1 PIG-P DUF4229 PF14012.6 CRK17882.1 - 0.36 11.0 3.6 0.16 12.1 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) LapA_dom PF06305.11 CRK17882.1 - 5.1 7.0 6.6 0.2 11.5 0.7 1.7 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DPM2 PF07297.12 CRK17883.1 - 6.5e-32 109.7 1.8 8.5e-32 109.3 1.8 1.1 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 CRK17883.1 - 0.0004 20.3 0.7 0.00065 19.6 0.7 1.3 1 0 0 1 1 1 1 PIG-P DUF4229 PF14012.6 CRK17883.1 - 0.65 10.1 4.2 0.19 11.9 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) LapA_dom PF06305.11 CRK17883.1 - 6.2 6.7 6.6 0.23 11.3 0.7 1.7 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain AAA PF00004.29 CRK17885.1 - 3.4e-47 160.2 0.0 7.2e-42 142.9 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CRK17885.1 - 2.9e-08 33.4 0.0 8.5e-08 31.9 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 CRK17885.1 - 2.8e-07 31.1 0.3 0.00092 19.6 0.2 3.4 2 1 0 2 2 2 2 AAA ATPase domain IstB_IS21 PF01695.17 CRK17885.1 - 9.4e-07 28.7 0.0 2.5e-05 24.1 0.0 2.8 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.14 CRK17885.1 - 4.2e-06 27.0 0.0 1.1e-05 25.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Bromodomain PF00439.25 CRK17885.1 - 0.00015 21.8 0.1 1.1 9.4 0.0 2.6 2 0 0 2 2 2 2 Bromodomain AAA_22 PF13401.6 CRK17885.1 - 0.0015 18.8 0.2 0.057 13.7 0.1 3.2 3 1 0 3 3 2 1 AAA domain AAA_5 PF07728.14 CRK17885.1 - 0.003 17.6 0.0 0.015 15.3 0.0 2.2 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 CRK17885.1 - 0.0044 17.4 0.4 0.036 14.5 0.0 2.8 4 0 0 4 4 2 1 RNA helicase AAA_33 PF13671.6 CRK17885.1 - 0.013 15.6 1.4 0.066 13.4 0.0 3.0 3 0 0 3 3 2 0 AAA domain TIP49 PF06068.13 CRK17885.1 - 0.015 14.5 0.0 0.029 13.6 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain ROQ_II PF18386.1 CRK17885.1 - 0.015 15.1 0.5 8.6 6.3 0.1 2.7 2 0 0 2 2 2 0 Roquin II domain AAA_14 PF13173.6 CRK17885.1 - 0.024 14.7 0.0 0.079 13.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain Latarcin PF10279.9 CRK17885.1 - 0.03 14.7 1.4 3.6 8.0 0.3 3.2 2 0 0 2 2 2 0 Latarcin precursor RuvB_N PF05496.12 CRK17885.1 - 0.034 13.9 0.0 0.079 12.7 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 CRK17885.1 - 0.058 13.9 0.0 0.23 12.0 0.0 2.1 1 0 0 1 1 1 0 AAA domain Rotavirus_VP7 PF05868.11 CRK17885.1 - 0.058 12.8 0.0 12 5.2 0.0 2.2 2 0 0 2 2 2 0 Rotavirus major outer capsid protein VP7 ABC_tran PF00005.27 CRK17885.1 - 0.073 13.6 3.5 0.19 12.3 0.0 3.5 3 1 0 3 3 2 0 ABC transporter AAA_28 PF13521.6 CRK17885.1 - 0.079 13.2 0.0 0.39 10.9 0.0 2.3 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 CRK17885.1 - 0.085 12.2 0.1 0.21 11.0 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Rad60-SLD_2 PF13881.6 CRK17885.1 - 0.086 13.0 0.5 26 5.0 0.0 2.9 3 0 0 3 3 2 0 Ubiquitin-2 like Rad60 SUMO-like AAA_7 PF12775.7 CRK17885.1 - 0.099 12.2 0.0 0.28 10.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_3 PF07726.11 CRK17885.1 - 0.17 11.8 0.0 0.42 10.5 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Yop-YscD_cpl PF16697.5 CRK17885.1 - 0.22 11.9 0.8 36 4.8 0.1 2.6 2 0 0 2 2 2 0 Inner membrane component of T3SS, cytoplasmic domain ATF7IP_BD PF16788.5 CRK17885.1 - 6.1 6.9 6.5 1 9.4 0.1 3.0 3 0 0 3 3 3 0 ATF-interacting protein binding domain Auxin_repressed PF05564.12 CRK17886.1 - 0.014 16.1 0.4 0.015 15.9 0.4 1.1 1 0 0 1 1 1 0 Dormancy/auxin associated protein Carb_anhydrase PF00194.21 CRK17887.1 - 2.3e-34 119.1 0.1 4.3e-34 118.2 0.1 1.3 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase CA_like PF10563.9 CRK17887.1 - 0.0093 15.9 0.3 4.1 7.3 0.2 2.3 1 1 1 2 2 2 2 Putative carbonic anhydrase Dus PF01207.17 CRK17890.1 - 2.7e-53 181.1 0.0 9.8e-53 179.2 0.0 1.8 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) BKACE PF05853.12 CRK17890.1 - 0.17 11.1 0.2 2.2 7.5 0.0 2.2 2 0 0 2 2 2 0 beta-keto acid cleavage enzyme adh_short PF00106.25 CRK17891.1 - 5.8e-25 87.9 0.1 4.3e-19 68.7 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CRK17891.1 - 2.7e-18 66.4 0.1 1.2e-16 61.0 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK17891.1 - 0.00086 19.3 0.0 0.0013 18.7 0.0 1.2 1 0 0 1 1 1 1 KR domain DSBA PF01323.20 CRK17893.1 - 1.8e-15 57.2 0.0 3.2e-15 56.4 0.0 1.4 1 1 0 1 1 1 1 DSBA-like thioredoxin domain BCNT PF07572.12 CRK17894.1 - 3.6e-23 81.4 2.1 7.3e-23 80.4 2.1 1.5 1 0 0 1 1 1 1 Bucentaur or craniofacial development Bromodomain PF00439.25 CRK17895.1 - 1.3e-20 73.3 0.1 3e-20 72.1 0.1 1.6 1 0 0 1 1 1 1 Bromodomain SnAC PF14619.6 CRK17895.1 - 2.1e-06 28.3 7.3 2.1e-06 28.3 7.3 2.8 3 2 0 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex QLQ PF08880.11 CRK17895.1 - 0.00054 19.7 2.0 0.00054 19.7 2.0 3.8 3 0 0 3 3 3 1 QLQ LMF1 PF06762.14 CRK17895.1 - 0.22 10.6 0.2 0.32 10.1 0.2 1.2 1 0 0 1 1 1 0 Lipase maturation factor TFIIA PF03153.13 CRK17895.1 - 8.3 6.3 31.4 0.26 11.3 24.4 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit HET PF06985.11 CRK17896.1 - 2.6e-19 70.0 3.8 3.7e-19 69.5 0.0 2.6 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) His_biosynth PF00977.21 CRK17896.1 - 8.7e-15 54.8 0.0 1.4e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 Histidine biosynthesis protein Ribul_P_3_epim PF00834.19 CRK17896.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family DUF3915 PF13054.6 CRK17896.1 - 3 7.9 6.9 5.9 6.9 6.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) PH PF00169.29 CRK17897.1 - 0.0077 16.7 0.0 0.018 15.5 0.0 1.8 1 0 0 1 1 1 1 PH domain RPOL_N PF14700.6 CRK17899.1 - 1.3e-55 189.2 0.1 1.4e-55 189.0 0.1 1.0 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal E1-N PF14463.6 CRK17899.1 - 0.024 14.4 0.3 0.037 13.9 0.3 1.2 1 0 0 1 1 1 0 E1 N-terminal domain DEAD PF00270.29 CRK17902.1 - 7.2e-17 61.7 0.0 8.7e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CRK17902.1 - 0.00044 20.3 0.0 0.00054 20.0 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Bse634I PF07832.11 CRK17902.1 - 0.092 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Cfr10I/Bse634I restriction endonuclease NDK PF00334.19 CRK17904.1 - 1.5e-31 109.2 0.0 1.7e-31 109.0 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase RPN2_C PF18004.1 CRK17909.1 - 2.7e-32 111.9 1.6 3.7e-32 111.5 1.6 1.2 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 CRK17909.1 - 0.0026 18.1 0.8 0.0072 16.7 0.8 1.8 1 0 0 1 1 1 1 Proteasome/cyclosome repeat AAA PF00004.29 CRK17911.1 - 7.7e-12 45.8 0.1 1.3e-11 45.1 0.1 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.15 CRK17911.1 - 0.0011 19.2 0.0 0.0034 17.7 0.0 1.8 2 0 0 2 2 2 1 FtsH Extracellular AAA_16 PF13191.6 CRK17911.1 - 0.0013 19.1 0.0 0.015 15.7 0.1 2.0 2 0 0 2 2 2 1 AAA ATPase domain TIP49 PF06068.13 CRK17911.1 - 0.0017 17.7 0.0 0.0022 17.3 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 CRK17911.1 - 0.014 15.2 0.3 0.041 13.6 0.3 1.7 1 1 0 1 1 1 0 IstB-like ATP binding protein RuvB_N PF05496.12 CRK17911.1 - 0.014 15.1 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CRK17911.1 - 0.027 14.4 0.0 0.041 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 CRK17911.1 - 0.059 12.8 0.2 0.1 12.0 0.2 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 CRK17911.1 - 0.067 13.4 0.1 0.24 11.6 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 CRK17911.1 - 0.08 13.2 0.1 0.19 12.0 0.1 1.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 CRK17911.1 - 0.11 12.6 0.1 0.2 11.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 CRK17911.1 - 0.12 12.4 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 CRK17911.1 - 0.22 11.0 0.0 0.32 10.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 CRK17911.1 - 0.25 10.7 0.4 0.41 10.0 0.4 1.2 1 0 0 1 1 1 0 PhoH-like protein Snf7 PF03357.21 CRK17921.1 - 2.9e-43 147.4 13.4 3.5e-43 147.2 13.4 1.0 1 0 0 1 1 1 1 Snf7 YscO-like PF16789.5 CRK17921.1 - 0.0016 18.5 7.1 0.0026 17.8 7.1 1.3 1 0 0 1 1 1 1 YscO-like protein MscS_porin PF12795.7 CRK17921.1 - 0.0051 16.4 11.1 0.62 9.6 5.3 2.3 1 1 1 2 2 2 2 Mechanosensitive ion channel porin domain NPV_P10 PF05531.12 CRK17921.1 - 0.006 17.0 9.1 0.48 10.9 0.1 3.1 2 1 1 3 3 3 2 Nucleopolyhedrovirus P10 protein Alpha-2-MRAP_C PF06401.11 CRK17921.1 - 0.016 15.2 4.9 0.038 14.0 4.2 1.8 1 1 1 2 2 2 0 Alpha-2-macroglobulin RAP, C-terminal domain Atg14 PF10186.9 CRK17921.1 - 0.019 14.1 6.9 0.023 13.8 6.9 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FlaC_arch PF05377.11 CRK17921.1 - 0.021 15.2 6.7 1.4 9.3 0.0 3.6 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) CLZ PF16526.5 CRK17921.1 - 0.041 14.2 10.7 0.24 11.8 0.1 3.4 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Exonuc_VII_L PF02601.15 CRK17921.1 - 0.064 12.8 3.1 0.075 12.6 3.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2205 PF10224.9 CRK17921.1 - 0.072 13.1 6.8 0.9 9.6 2.9 3.1 2 1 1 3 3 3 0 Short coiled-coil protein DUF4201 PF13870.6 CRK17921.1 - 0.091 12.5 10.5 0.32 10.7 9.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Prefoldin PF02996.17 CRK17921.1 - 0.13 12.2 9.4 1.5 8.8 0.1 3.5 3 1 0 3 3 3 0 Prefoldin subunit Prefoldin_2 PF01920.20 CRK17921.1 - 0.26 11.3 0.0 0.26 11.3 0.0 3.6 2 1 2 4 4 4 0 Prefoldin subunit FapA PF03961.13 CRK17921.1 - 0.32 9.6 8.7 0.85 8.1 5.9 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A DUF848 PF05852.11 CRK17921.1 - 0.32 11.1 6.4 0.33 11.1 4.3 2.0 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) ADIP PF11559.8 CRK17921.1 - 0.35 11.0 10.4 6.1 6.9 0.7 2.5 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Endotoxin_N PF03945.14 CRK17921.1 - 0.38 10.4 4.8 1.2 8.9 0.1 2.1 1 1 1 2 2 2 0 delta endotoxin, N-terminal domain Spc7 PF08317.11 CRK17921.1 - 0.51 9.2 12.2 1.3 7.8 11.9 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein bZIP_1 PF00170.21 CRK17921.1 - 0.67 10.1 7.0 2.1 8.5 0.1 3.3 2 1 0 2 2 2 0 bZIP transcription factor DUF4407 PF14362.6 CRK17921.1 - 0.72 9.1 8.9 1.1 8.5 8.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) GrpE PF01025.19 CRK17921.1 - 0.76 9.4 10.4 1.9 8.1 8.2 2.2 1 1 1 2 2 2 0 GrpE DASH_Dam1 PF08653.10 CRK17921.1 - 1.2 9.0 6.4 11 6.0 0.1 3.5 3 1 0 3 3 3 0 DASH complex subunit Dam1 Mod_r PF07200.13 CRK17921.1 - 1.4 9.0 11.8 0.95 9.6 8.0 2.0 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Muted PF14942.6 CRK17921.1 - 1.6 9.1 9.8 3.2 8.1 6.9 2.1 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein DUF4446 PF14584.6 CRK17921.1 - 2.5 8.1 8.4 14 5.6 5.6 2.6 1 1 3 4 4 4 0 Protein of unknown function (DUF4446) FUSC PF04632.12 CRK17921.1 - 2.6 6.5 4.6 4.6 5.7 3.2 1.7 1 1 1 2 2 2 0 Fusaric acid resistance protein family Cluap1 PF10234.9 CRK17921.1 - 3.5 6.9 11.7 13 5.1 7.5 2.1 1 1 1 2 2 2 0 Clusterin-associated protein-1 DUF4094 PF13334.6 CRK17921.1 - 4.3 7.8 6.8 8.3 6.9 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) TMPIT PF07851.13 CRK17921.1 - 4.9 6.3 8.8 4.9 6.3 7.0 1.6 1 1 1 2 2 2 0 TMPIT-like protein SlyX PF04102.12 CRK17921.1 - 6 7.6 13.4 11 6.7 0.1 3.5 1 1 2 3 3 3 0 SlyX CCDC-167 PF15188.6 CRK17921.1 - 6 7.3 9.8 9.8 6.6 3.3 3.2 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 Uso1_p115_C PF04871.13 CRK17921.1 - 9.2 6.7 18.3 1e+02 3.3 18.1 2.4 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Carb_anhydrase PF00194.21 CRK17946.1 - 1.2e-20 74.1 0.1 2.3e-20 73.2 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase GST_N_2 PF13409.6 CRK17946.1 - 1.6e-07 31.5 0.0 3.2e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 CRK17946.1 - 5.8e-06 26.6 0.0 1.4e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CRK17946.1 - 2.9e-05 24.0 1.2 0.00012 22.1 1.1 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CRK17946.1 - 0.015 15.5 0.0 0.039 14.1 0.0 1.9 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CRK17946.1 - 0.82 9.9 0.0 0.82 9.9 0.0 2.2 1 1 1 2 2 2 0 Glutathione S-transferase, C-terminal domain CPSF100_C PF13299.6 CRK17946.1 - 1.6 8.9 6.5 2.3 8.4 4.3 2.0 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF3425 PF11905.8 CRK17947.1 - 5.6e-17 61.9 0.0 1e-16 61.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) TauD PF02668.16 CRK17949.1 - 1.4e-62 212.0 0.5 1.7e-62 211.7 0.5 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family NACHT PF05729.12 CRK17950.1 - 1.6e-07 31.4 0.0 4.6e-07 29.9 0.0 1.8 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 CRK17950.1 - 1.5e-05 25.5 0.4 0.00025 21.4 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 CRK17950.1 - 0.00014 22.3 0.0 0.0021 18.5 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CRK17950.1 - 0.029 14.7 2.5 0.23 11.7 0.0 3.4 3 1 0 3 3 3 0 AAA domain AAA_29 PF13555.6 CRK17950.1 - 0.059 13.1 0.1 0.14 11.9 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.22 CRK17950.1 - 0.091 11.9 0.0 0.2 10.8 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain UNC80 PF15778.5 CRK17950.1 - 0.11 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Cation channel complex component UNC80 7TMR-HDED PF07697.11 CRK17950.1 - 0.26 11.4 1.1 0.5 10.4 0.7 1.6 2 0 0 2 2 2 0 7TM-HD extracellular FA_hydroxylase PF04116.13 CRK17951.1 - 3.2e-07 30.7 8.4 3.2e-07 30.7 8.4 2.1 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily RmlD_sub_bind PF04321.17 CRK17951.1 - 0.1 11.7 0.1 0.16 11.0 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Epimerase PF01370.21 CRK17951.1 - 0.15 11.5 0.4 0.58 9.6 0.4 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family HgmA PF04209.13 CRK17952.1 - 1.3e-186 620.4 0.0 1.5e-186 620.2 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Exo_endo_phos PF03372.23 CRK17953.1 - 1.5e-08 34.4 1.3 3.5e-08 33.3 1.3 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ank_2 PF12796.7 CRK17954.1 - 5.4e-32 110.2 0.9 5.9e-08 33.2 0.1 5.3 2 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 CRK17954.1 - 1.1e-24 85.8 0.2 0.015 15.7 0.0 7.6 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.6 CRK17954.1 - 2.1e-23 79.8 0.8 0.016 15.7 0.0 7.9 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.6 CRK17954.1 - 3.2e-23 81.8 1.4 7.5e-05 23.2 0.1 5.9 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 CRK17954.1 - 1.2e-21 76.4 3.5 0.00039 20.7 0.1 6.3 4 2 3 7 7 7 6 Ankyrin repeats (many copies) Helo_like_N PF17111.5 CRK17954.1 - 0.0011 18.4 1.0 0.0025 17.2 1.0 1.6 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins SesA PF17107.5 CRK17954.1 - 0.027 14.6 0.1 0.063 13.5 0.1 1.6 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Methyltransf_23 PF13489.6 CRK17955.1 - 4.3e-36 124.2 0.0 5.8e-36 123.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK17955.1 - 4.3e-12 46.6 0.0 9.6e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CRK17955.1 - 3.4e-11 43.7 0.0 5.8e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK17955.1 - 1.5e-10 41.1 0.0 3.6e-10 39.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK17955.1 - 5e-09 36.8 0.0 1.3e-08 35.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 CRK17955.1 - 0.00054 19.6 0.0 0.00085 19.0 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_2 PF00891.18 CRK17955.1 - 0.0017 17.7 0.0 0.0028 17.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Ubie_methyltran PF01209.18 CRK17955.1 - 0.0088 15.4 0.0 0.029 13.7 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 CRK17955.1 - 0.054 13.6 0.0 0.099 12.7 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 CRK17955.1 - 0.21 11.1 0.0 1.7 8.1 0.0 2.0 2 0 0 2 2 2 0 Putative methyltransferase PBP PF01161.20 CRK17957.1 - 7e-19 68.4 0.1 1e-18 68.0 0.1 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Glyco_hydro_12 PF01670.16 CRK17958.1 - 3.9e-42 144.7 5.8 5.1e-42 144.3 5.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 CBM_1 PF00734.18 CRK17958.1 - 1.8e-10 40.6 19.5 1.8e-10 40.6 19.5 2.9 4 0 0 4 4 4 1 Fungal cellulose binding domain Toxin_7 PF05980.12 CRK17958.1 - 0.07 13.4 9.2 0.18 12.1 9.2 1.8 1 0 0 1 1 1 0 Toxin 7 Haem_degrading PF03928.14 CRK17958.1 - 0.093 12.8 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 Haem-degrading MFS_1 PF07690.16 CRK17959.1 - 1.5e-21 76.7 29.6 1.5e-21 76.7 29.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily FAM176 PF14851.6 CRK17959.1 - 0.049 13.3 0.0 0.27 10.9 0.0 2.1 2 0 0 2 2 2 0 FAM176 family DUF4212 PF13937.6 CRK17959.1 - 0.066 13.6 2.2 3.1 8.2 1.0 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4212) GWT1 PF06423.12 CRK17959.1 - 0.64 10.1 9.3 1.6 8.8 0.4 3.5 2 1 1 3 3 3 0 GWT1 dCMP_cyt_deam_1 PF00383.23 CRK17961.1 - 3.6e-07 30.0 0.0 5.3e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CRK17961.1 - 2.6e-06 27.2 0.0 4.1e-06 26.6 0.0 1.3 1 1 0 1 1 1 1 MafB19-like deaminase Prok-JAB PF14464.6 CRK17961.1 - 0.16 11.8 0.1 0.27 11.0 0.1 1.4 1 0 0 1 1 1 0 Prokaryotic homologs of the JAB domain Methyltransf_16 PF10294.9 CRK17963.1 - 9.4e-29 100.4 0.0 1.5e-28 99.7 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 CRK17963.1 - 0.06 13.2 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain adh_short_C2 PF13561.6 CRK17964.1 - 2.4e-50 171.3 0.0 2.8e-50 171.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRK17964.1 - 2e-41 141.6 0.0 2.6e-41 141.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CRK17964.1 - 7.3e-11 42.3 0.0 1e-10 41.9 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CRK17964.1 - 0.036 13.5 0.0 0.52 9.7 0.0 2.2 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Glyco_transf_4 PF13439.6 CRK17964.1 - 0.12 12.3 0.3 7.7 6.5 0.1 2.2 2 0 0 2 2 2 0 Glycosyltransferase Family 4 Glyco_hydro_61 PF03443.14 CRK17965.1 - 2.7e-46 158.1 0.1 3.4e-46 157.8 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 CRK17965.1 - 2.7e-09 36.8 8.5 2.7e-09 36.8 8.5 2.3 1 1 0 1 1 1 1 Fungal cellulose binding domain HpcH_HpaI PF03328.14 CRK17966.1 - 6.9e-21 74.4 0.0 9.7e-21 73.9 0.0 1.3 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Fungal_trans PF04082.18 CRK17966.1 - 0.079 12.0 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK17967.1 - 1.2e-07 31.8 10.1 3.2e-07 30.3 10.1 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 CRK17967.1 - 0.042 12.9 0.0 0.065 12.2 0.0 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain Cas1_AcylT PF07779.12 CRK17968.1 - 2.8e-114 382.7 12.5 6.2e-114 381.5 12.5 1.5 1 1 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p PC-Esterase PF13839.6 CRK17968.1 - 0.071 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Protoglobin PF11563.8 CRK17969.1 - 2.4e-56 190.0 0.1 2.9e-56 189.7 0.1 1.1 1 0 0 1 1 1 1 Protoglobin DAO_C PF16901.5 CRK17970.1 - 0.2 11.5 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 C-terminal domain of alpha-glycerophosphate oxidase Glyco_hydro_61 PF03443.14 CRK17972.1 - 1.5e-15 57.7 0.0 1.7e-15 57.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Fungal_trans_2 PF11951.8 CRK17980.1 - 3.8e-08 32.5 0.0 5.7e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aminotran_3 PF00202.21 CRK17985.1 - 3.9e-22 78.5 0.0 4e-22 78.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III NCE101 PF11654.8 CRK17986.1 - 4.4e-08 32.7 0.0 4.6e-08 32.6 0.0 1.0 1 0 0 1 1 1 1 Non-classical export protein 1 PH_9 PF15410.6 CRK17989.1 - 6.1e-20 71.8 0.1 7.5e-20 71.5 0.1 1.1 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 CRK17989.1 - 0.031 14.8 0.0 0.13 12.7 0.0 1.8 1 1 0 1 1 1 0 PH domain Phosducin PF02114.16 CRK17990.1 - 0.00011 21.3 0.1 0.00039 19.4 0.1 1.8 1 1 0 1 1 1 1 Phosducin ECH_2 PF16113.5 CRK17995.1 - 4.5e-50 171.0 0.0 4.9e-50 170.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Polysacc_deac_1 PF01522.21 CRK17995.1 - 0.13 12.1 0.4 0.23 11.4 0.4 1.5 1 1 0 1 1 1 0 Polysaccharide deacetylase zf-C2H2_4 PF13894.6 CRK18013.1 - 3e-10 40.0 13.4 0.021 15.6 0.8 5.5 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2 PF00096.26 CRK18013.1 - 1.4e-07 31.6 13.1 0.085 13.4 0.5 5.2 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 CRK18013.1 - 4.6e-05 23.3 10.2 0.0028 17.6 0.8 3.9 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 CRK18013.1 - 0.00011 22.4 5.8 0.0018 18.5 1.5 2.6 2 0 0 2 2 2 1 C2H2-type zinc ribbon zf-met PF12874.7 CRK18013.1 - 0.00078 19.8 0.8 9 6.8 0.2 4.4 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CRK18013.1 - 0.0085 16.4 1.3 1.7 9.0 0.6 4.2 5 0 0 5 5 4 1 Zinc-finger double-stranded RNA-binding zf-C2H2_aberr PF17017.5 CRK18013.1 - 0.048 13.8 1.4 0.96 9.6 0.0 2.6 2 0 0 2 2 2 0 Aberrant zinc-finger zf-H2C2_2 PF13465.6 CRK18013.1 - 0.076 13.5 17.3 0.88 10.1 0.3 5.2 5 0 0 5 5 5 0 Zinc-finger double domain zf-C2H2_2 PF12756.7 CRK18013.1 - 0.082 13.2 9.8 3.3 8.1 0.3 4.4 2 2 3 5 5 5 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_4 PF13717.6 CRK18013.1 - 0.16 11.9 7.2 8.8 6.3 0.0 4.1 4 0 0 4 4 4 0 zinc-ribbon domain zf-Di19 PF05605.12 CRK18013.1 - 0.24 11.7 13.0 0.4 11.0 0.2 3.5 2 2 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.10 CRK18013.1 - 0.3 11.3 6.7 1.7 8.9 0.4 3.6 2 2 1 3 3 3 0 Zinc ribbon domain IBR PF01485.21 CRK18013.1 - 0.3 11.3 7.4 3.7 7.9 0.0 3.2 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain zf-C2H2_9 PF16293.5 CRK18013.1 - 0.38 10.6 7.3 9 6.2 0.2 4.0 4 1 0 4 4 4 0 C2H2 type zinc-finger (1 copy) zinc_ribbon_5 PF13719.6 CRK18013.1 - 0.81 9.5 10.0 4.4 7.1 1.8 3.8 3 1 0 3 3 3 0 zinc-ribbon domain zf-C2H2_11 PF16622.5 CRK18013.1 - 1.5 8.6 14.8 1.3 8.8 0.7 3.5 4 0 0 4 4 4 0 zinc-finger C2H2-type zf_UBZ PF18439.1 CRK18013.1 - 1.8 8.3 4.4 4.1 7.1 0.1 3.6 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger DHHC PF01529.20 CRK18015.1 - 1.5e-37 128.7 8.1 1.5e-37 128.7 8.1 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase Tau95_N PF17682.1 CRK18017.1 - 9.7e-34 116.3 0.0 1.8e-33 115.4 0.0 1.5 1 0 0 1 1 1 1 Tau95 Triple barrel domain Tau95 PF09734.9 CRK18017.1 - 3.9e-32 112.0 0.1 8.3e-32 110.9 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain B56 PF01603.20 CRK18019.1 - 2.9e-193 642.5 5.3 3.4e-193 642.3 5.3 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 CRK18019.1 - 0.0007 19.5 2.0 0.28 11.1 0.0 2.4 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal SBF2 PF12335.8 CRK18019.1 - 0.1 12.2 0.1 0.29 10.7 0.1 1.7 1 0 0 1 1 1 0 Myotubularin protein CTD_bind PF04818.13 CRK18021.1 - 1.5e-13 51.4 0.0 2e-12 47.7 0.0 2.5 3 0 0 3 3 3 1 RNA polymerase II-binding domain. HMGL-like PF00682.19 CRK18023.1 - 1.2e-79 267.6 0.7 1.8e-79 267.0 0.7 1.3 1 0 0 1 1 1 1 HMGL-like Trp_syntA PF00290.20 CRK18023.1 - 0.079 11.8 0.0 12 4.6 0.0 2.5 2 0 0 2 2 2 0 Tryptophan synthase alpha chain Exo_endo_phos PF03372.23 CRK18028.1 - 1.1e-10 41.5 0.5 3.1e-10 40.0 0.1 2.0 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family BBS2_Mid PF14783.6 CRK18028.1 - 0.086 12.9 0.5 0.47 10.5 0.0 2.5 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region WD40 PF00400.32 CRK18028.1 - 0.31 12.0 3.2 2.4 9.2 0.1 3.9 5 0 0 5 5 5 0 WD domain, G-beta repeat Orn_Arg_deC_N PF02784.16 CRK18030.1 - 1.5e-82 276.7 0.0 2e-82 276.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 CRK18030.1 - 3.6e-20 72.0 0.0 1e-19 70.5 0.0 1.9 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Peptidase_M16_C PF05193.21 CRK18032.1 - 0.17 11.9 0.0 0.8 9.7 0.0 1.8 2 0 0 2 2 2 0 Peptidase M16 inactive domain Peptidase_M16_C PF05193.21 CRK18034.1 - 7.2e-21 75.0 0.0 3e-20 73.0 0.0 1.9 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 CRK18034.1 - 6e-08 32.8 0.1 1.5e-07 31.5 0.0 1.6 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) UvrA_inter PF17760.1 CRK18034.1 - 0.00064 19.8 0.1 0.064 13.3 0.0 2.5 2 0 0 2 2 2 1 UvrA interaction domain M16C_assoc PF08367.11 CRK18034.1 - 0.054 12.6 0.5 0.084 12.0 0.5 1.3 1 0 0 1 1 1 0 Peptidase M16C associated Taxilin PF09728.9 CRK18035.1 - 3.9e-50 170.8 35.4 3.9e-50 170.8 35.4 1.3 2 0 0 2 2 2 1 Myosin-like coiled-coil protein Fez1 PF06818.15 CRK18035.1 - 1.6 9.2 32.4 2.7 8.4 5.1 2.1 2 0 0 2 2 2 0 Fez1 TMF_TATA_bd PF12325.8 CRK18035.1 - 7 6.9 36.7 0.15 12.3 7.7 3.7 1 1 3 4 4 4 0 TATA element modulatory factor 1 TATA binding M16C_assoc PF08367.11 CRK18037.1 - 2.3e-86 289.0 0.0 3.4e-86 288.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 CRK18037.1 - 4.6e-20 72.4 0.1 2.8e-19 69.9 0.0 2.3 3 0 0 3 3 3 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 CRK18037.1 - 1.9e-08 34.4 0.2 3e-07 30.5 0.0 2.7 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) UvrA_inter PF17760.1 CRK18037.1 - 0.0055 16.8 0.1 0.11 12.6 0.0 2.5 2 0 0 2 2 2 1 UvrA interaction domain Taxilin PF09728.9 CRK18039.1 - 2.3e-89 299.6 60.4 3.5e-89 299.0 60.4 1.3 1 0 0 1 1 1 1 Myosin-like coiled-coil protein DUF4810 PF16068.5 CRK18039.1 - 0.0027 18.2 0.2 0.0027 18.2 0.2 5.7 6 2 1 7 7 7 1 Domain of unknown function (DUF4810) Mcm10 PF09332.11 CRK18042.1 - 0.074 12.5 1.5 0.1 12.0 1.5 1.1 1 0 0 1 1 1 0 Mcm10 replication factor NMO PF03060.15 CRK18043.1 - 2.2e-50 171.9 0.3 3.2e-50 171.4 0.3 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 CRK18043.1 - 2.7e-07 29.9 0.3 5.1e-06 25.7 0.3 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 CRK18043.1 - 0.042 12.9 6.2 0.022 13.8 4.1 1.5 2 0 0 2 2 2 0 FMN-dependent dehydrogenase Baculo_PEP_C PF04513.12 CRK18044.1 - 0.12 12.4 0.5 0.18 11.8 0.5 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus SNF2_N PF00176.23 CRK18045.1 - 3.9e-44 150.8 0.1 8.4e-44 149.7 0.1 1.4 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 CRK18045.1 - 9.2e-08 32.3 0.1 1.7e-07 31.4 0.1 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CRK18045.1 - 3.9e-06 27.2 0.0 1.1e-05 25.7 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_34 PF13872.6 CRK18045.1 - 0.01 14.7 0.0 0.017 14.0 0.0 1.2 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 Zn_Tnp_IS91 PF14319.6 CRK18045.1 - 0.1 12.7 1.8 0.21 11.6 1.8 1.5 1 0 0 1 1 1 0 Transposase zinc-binding domain AT_hook PF02178.19 CRK18045.1 - 5.2 7.3 6.7 1.3 9.1 2.2 2.6 2 0 0 2 2 2 0 AT hook motif LRR_6 PF13516.6 CRK18046.1 - 0.00025 20.9 1.4 23 5.4 0.0 5.6 7 0 0 7 7 7 3 Leucine Rich repeat LRR_4 PF12799.7 CRK18046.1 - 0.0027 18.1 5.2 6.3 7.4 0.0 5.9 5 3 2 7 7 7 2 Leucine Rich repeats (2 copies) CDC45 PF02724.14 CRK18046.1 - 0.11 10.8 5.8 0.15 10.4 5.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Lipase_3 PF01764.25 CRK18047.1 - 9.5e-36 122.8 0.0 1.5e-35 122.2 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Lipase3_N PF03893.16 CRK18047.1 - 2.3e-05 24.3 0.7 5.1e-05 23.2 0.2 1.8 2 0 0 2 2 2 1 Lipase 3 N-terminal region Abhydrolase_6 PF12697.7 CRK18047.1 - 0.044 14.4 0.1 0.063 13.9 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CRK18047.1 - 0.066 12.5 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Cutinase PF01083.22 CRK18047.1 - 0.23 11.4 5.2 0.22 11.5 1.1 2.7 2 1 0 2 2 2 0 Cutinase Glyco_hydro_3 PF00933.21 CRK18048.1 - 5.4e-41 141.0 0.0 9e-41 140.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 CRK18048.1 - 2.4e-33 115.8 0.2 6.7e-31 107.8 0.0 2.6 1 1 1 2 2 2 2 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 CRK18048.1 - 2.2e-23 82.1 0.0 4e-23 81.3 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Peptidase_S10 PF00450.22 CRK18049.1 - 2.2e-65 221.7 0.0 7.1e-65 220.0 0.0 1.6 1 1 0 1 1 1 1 Serine carboxypeptidase PT-TG PF14449.6 CRK18049.1 - 0.056 13.3 0.1 0.35 10.8 0.1 2.3 2 0 0 2 2 2 0 Pre-toxin TG Cutinase PF01083.22 CRK18051.1 - 4.7e-39 134.2 0.0 5.7e-39 133.9 0.0 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 CRK18051.1 - 0.0003 20.4 0.1 0.00044 19.9 0.1 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_2 PF02230.16 CRK18051.1 - 0.012 15.4 0.1 0.018 14.9 0.1 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 CRK18051.1 - 0.029 15.0 0.5 0.043 14.4 0.5 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family VirJ PF06057.11 CRK18051.1 - 0.052 13.4 0.0 0.073 12.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) DUF5082 PF16888.5 CRK18052.1 - 0.023 15.0 0.0 0.49 10.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Trp_syntA PF00290.20 CRK18054.1 - 2.9e-62 209.8 0.0 6.2e-62 208.8 0.0 1.4 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 CRK18054.1 - 3.7e-49 167.7 2.1 5.6e-49 167.1 2.1 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Ribosomal_L28 PF00830.19 CRK18055.1 - 2.6e-17 62.8 0.9 3.8e-17 62.2 0.9 1.3 1 0 0 1 1 1 1 Ribosomal L28 family PALP PF00291.25 CRK18056.1 - 1.7e-49 168.8 2.1 2.7e-49 168.1 2.1 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Trp_syntA PF00290.20 CRK18056.1 - 8.3e-47 159.2 0.2 8.2e-33 113.3 0.1 2.5 1 1 1 2 2 2 2 Tryptophan synthase alpha chain Baculo_PEP_C PF04513.12 CRK18057.1 - 0.0016 18.5 6.3 1.3 9.1 0.9 3.8 3 1 1 4 4 4 2 Baculovirus polyhedron envelope protein, PEP, C terminus ERGIC_N PF13850.6 CRK18057.1 - 0.006 16.9 0.1 0.016 15.5 0.1 1.7 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) ATP-cone PF03477.16 CRK18057.1 - 0.13 12.9 0.0 0.63 10.7 0.0 2.2 1 1 0 1 1 1 0 ATP cone domain DUF2116 PF09889.9 CRK18057.1 - 3.2 7.8 4.3 1 9.4 0.2 2.2 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Abhydrolase_9_N PF15420.6 CRK18057.1 - 5.7 6.9 13.7 0.069 13.2 3.5 2.5 2 2 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus Methyltransf_23 PF13489.6 CRK18058.1 - 1.4e-14 54.3 0.0 2.4e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CRK18058.1 - 5.5e-07 30.1 0.0 2.4e-06 28.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK18058.1 - 2.7e-06 28.0 0.0 1e-05 26.1 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK18058.1 - 0.00033 21.4 0.0 0.0014 19.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain DUF2388 PF09498.10 CRK18058.1 - 0.0022 18.0 0.1 0.0045 16.9 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2388) Methyltransf_31 PF13847.6 CRK18058.1 - 0.0042 16.9 0.0 0.024 14.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 CRK18058.1 - 0.085 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family 6PF2K PF01591.18 CRK18059.1 - 2.2e-82 275.7 0.5 3.2e-82 275.2 0.5 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 CRK18059.1 - 1.3e-34 119.6 0.0 2.3e-34 118.8 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Asp PF00026.23 CRK18059.1 - 1.3e-29 103.6 0.3 2.3e-28 99.5 0.3 2.2 1 1 0 1 1 1 1 Eukaryotic aspartyl protease AAA_33 PF13671.6 CRK18059.1 - 1.2e-06 28.8 0.1 2.6e-06 27.7 0.1 1.6 1 0 0 1 1 1 1 AAA domain Asp_protease_2 PF13650.6 CRK18059.1 - 4.6e-05 24.0 0.2 0.86 10.3 0.0 3.6 3 0 0 3 3 3 1 Aspartyl protease KTI12 PF08433.10 CRK18059.1 - 0.00075 19.0 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 gag-asp_proteas PF13975.6 CRK18059.1 - 0.038 14.5 0.3 18 6.0 0.0 3.5 3 1 0 3 3 3 0 gag-polyprotein putative aspartyl protease DEAD PF00270.29 CRK18060.1 - 4.6e-45 153.5 0.0 9e-45 152.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase WD40 PF00400.32 CRK18060.1 - 2.7e-13 50.2 4.2 0.00012 22.7 0.1 4.7 4 0 0 4 4 4 2 WD domain, G-beta repeat Helicase_C PF00271.31 CRK18060.1 - 4.8e-10 39.8 0.1 1.6e-09 38.0 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ATP_bind_3 PF01171.20 CRK18060.1 - 1.4e-08 34.7 0.0 2.6e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 PP-loop family ResIII PF04851.15 CRK18060.1 - 0.00021 21.3 1.8 0.00084 19.4 0.0 2.8 4 1 1 5 5 5 1 Type III restriction enzyme, res subunit BSP_II PF05432.11 CRK18060.1 - 0.011 15.5 11.5 0.017 14.8 11.5 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Nop14 PF04147.12 CRK18060.1 - 0.064 11.5 11.1 0.085 11.1 11.1 1.1 1 0 0 1 1 1 0 Nop14-like family ANAPC4_WD40 PF12894.7 CRK18060.1 - 0.11 12.8 0.1 1.1 9.7 0.0 2.5 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain FAM176 PF14851.6 CRK18060.1 - 7.1 6.3 8.1 14 5.3 8.1 1.4 1 0 0 1 1 1 0 FAM176 family Pox_Ag35 PF03286.14 CRK18060.1 - 7.2 6.4 16.7 13 5.5 16.7 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Transglut_core PF01841.19 CRK18067.1 - 0.0011 19.4 0.1 0.0021 18.5 0.1 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily ARID PF01388.21 CRK18070.1 - 6.1e-19 68.5 0.0 8.1e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain MADF_DNA_bdg PF10545.9 CRK18070.1 - 0.0019 18.5 0.0 0.0052 17.1 0.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase transcription factor Myb/SANT-like Mito_carr PF00153.27 CRK18073.1 - 8.8e-14 51.2 0.0 9.4e-14 51.1 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial carrier protein IMPDH PF00478.25 CRK18075.1 - 1.8e-31 109.4 0.0 1.9e-31 109.3 0.0 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 CRK18075.1 - 0.0063 15.9 0.0 0.0068 15.8 0.0 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase UDPG_MGDP_dh_C PF03720.15 CRK18077.1 - 1.2e-17 64.3 0.0 1.6e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 CRK18077.1 - 1.6e-12 47.4 0.0 3.2e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain ELYS-bb PF16687.5 CRK18077.1 - 0.1 11.2 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 beta-propeller of ELYS nucleoporin Gln-synt_C PF00120.24 CRK18080.1 - 3.7e-12 45.9 0.0 9.8e-12 44.5 0.0 1.6 2 0 0 2 2 2 1 Glutamine synthetase, catalytic domain Proteasome PF00227.26 CRK18084.1 - 2.5e-33 115.2 0.0 3.3e-33 114.8 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CRK18084.1 - 6.7e-13 48.1 0.0 1.9e-12 46.6 0.0 1.8 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Synaptobrevin PF00957.21 CRK18099.1 - 3.9e-32 109.9 0.3 5.4e-32 109.4 0.3 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 CRK18099.1 - 5.8e-29 100.0 0.0 1.2e-28 98.9 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain SUV3_C PF12513.8 CRK18101.1 - 2e-16 59.6 0.3 4.3e-16 58.6 0.3 1.6 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 CRK18101.1 - 2.8e-10 40.5 0.0 8e-10 39.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Suv3_C_1 PF18147.1 CRK18101.1 - 1.3e-07 31.3 0.2 4.1e-07 29.8 0.1 2.0 2 0 0 2 2 2 1 Suv3 C-terminal domain 1 Glyco_hydro_64 PF16483.5 CRK18103.1 - 1.9e-115 386.1 0.0 2.2e-115 385.8 0.0 1.0 1 0 0 1 1 1 1 Beta-1,3-glucanase PagP PF07017.11 CRK18103.1 - 0.12 11.8 0.0 0.27 10.6 0.0 1.6 1 0 0 1 1 1 0 Antimicrobial peptide resistance and lipid A acylation protein PagP FA_desaturase PF00487.24 CRK18105.1 - 7e-13 49.0 28.3 9.6e-10 38.7 11.0 2.4 2 1 1 3 3 3 2 Fatty acid desaturase DUF3474 PF11960.8 CRK18105.1 - 1.2e-05 25.5 0.0 2e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) LIDHydrolase PF10230.9 CRK18107.1 - 1.2e-57 195.5 0.0 1.4e-57 195.3 0.0 1.0 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 CRK18107.1 - 2.1e-05 25.2 4.4 2.6e-05 24.9 4.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CRK18107.1 - 0.0061 15.9 0.2 0.04 13.2 0.1 2.4 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 CRK18107.1 - 0.097 12.5 0.0 0.13 12.0 0.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold AA_permease PF00324.21 CRK18109.1 - 2.1e-128 428.9 31.7 2.5e-128 428.7 31.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CRK18109.1 - 7e-43 147.0 36.1 8.5e-43 146.7 36.1 1.1 1 0 0 1 1 1 1 Amino acid permease Na_Ala_symp PF01235.17 CRK18109.1 - 4.1 6.6 16.8 0.77 9.0 7.8 2.6 2 0 0 2 2 2 0 Sodium:alanine symporter family DUF924 PF06041.11 CRK18111.1 - 5.6e-37 127.6 0.0 7.6e-37 127.2 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) SH3-RhoG_link PF16609.5 CRK18111.1 - 0.13 12.0 0.7 0.27 11.0 0.7 1.5 1 0 0 1 1 1 0 SH3-RhoGEF linking unstructured region AA_permease_2 PF13520.6 CRK18113.1 - 3e-88 296.5 19.5 3e-88 296.5 19.5 2.0 2 0 0 2 2 2 1 Amino acid permease Peptidase_S8 PF00082.22 CRK18116.1 - 1.6e-42 145.8 1.6 2.4e-42 145.2 1.6 1.2 1 0 0 1 1 1 1 Subtilase family AA_permease PF00324.21 CRK18118.1 - 2.6e-136 455.0 33.9 3e-136 454.8 33.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CRK18118.1 - 4.6e-37 127.8 35.1 5.7e-37 127.5 35.1 1.0 1 0 0 1 1 1 1 Amino acid permease AnmK PF03702.14 CRK18120.1 - 5.2e-85 285.7 0.0 6.1e-85 285.5 0.0 1.0 1 0 0 1 1 1 1 Anhydro-N-acetylmuramic acid kinase Maf_N PF08383.11 CRK18120.1 - 0.0025 17.6 1.3 0.41 10.4 0.1 3.8 4 1 0 4 4 4 1 Maf N-terminal region DUF768 PF05589.11 CRK18120.1 - 0.039 14.0 0.0 0.088 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF768) Tudor_3 PF18115.1 CRK18123.1 - 0.13 12.1 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 DNA repair protein Crb2 Tudor domain Pkinase PF00069.25 CRK18125.1 - 4e-37 128.0 0.0 1.2e-36 126.5 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK18125.1 - 3.6e-12 46.1 0.0 2.2e-11 43.5 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CRK18125.1 - 0.14 10.9 0.1 0.25 10.1 0.1 1.4 1 1 0 1 1 1 0 Fungal protein kinase Nramp PF01566.18 CRK18126.1 - 1.6e-84 284.0 21.0 1.6e-84 284.0 21.0 2.1 2 1 0 2 2 2 1 Natural resistance-associated macrophage protein Renin_r PF07850.14 CRK18126.1 - 0.65 10.6 0.0 0.65 10.6 0.0 3.2 4 1 1 5 5 5 0 Renin receptor-like protein EVC2_like PF12297.8 CRK18126.1 - 1.4 7.5 2.1 2.5 6.7 2.1 1.3 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein Sugar_tr PF00083.24 CRK18129.1 - 7.1e-86 288.8 16.3 8.8e-86 288.5 16.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK18129.1 - 1.6e-27 96.4 46.9 7.8e-24 84.3 26.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 CRK18129.1 - 0.018 13.6 21.9 0.023 13.3 8.2 2.8 2 2 0 2 2 2 0 MFS/sugar transport protein Fungal_trans PF04082.18 CRK18131.1 - 2.8e-09 36.4 0.1 4.2e-09 35.8 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK18131.1 - 4.1e-05 23.6 11.6 6.8e-05 22.9 11.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fasciclin PF02469.22 CRK18133.1 - 4.6e-44 149.7 0.3 2.1e-25 89.4 0.1 2.1 2 0 0 2 2 2 2 Fasciclin domain BAR PF03114.18 CRK18136.1 - 1.3e-49 169.0 3.5 1.6e-49 168.7 3.5 1.1 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 CRK18136.1 - 2.6e-07 30.1 1.5 3.6e-07 29.6 1.5 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking DinB_2 PF12867.7 CRK18136.1 - 0.18 12.4 1.6 9.8 6.7 2.1 3.0 2 1 0 2 2 2 0 DinB superfamily PLDc_2 PF13091.6 CRK18137.1 - 1e-19 70.7 0.0 3.6e-14 52.8 0.0 2.8 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 CRK18137.1 - 0.0065 16.6 0.0 7.4 6.9 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif Ytp1 PF10355.9 CRK18138.1 - 1e-59 202.1 17.9 1e-59 202.1 17.9 2.6 1 1 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 CRK18138.1 - 8.7e-33 112.3 2.9 8.7e-33 112.3 2.9 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) Glyco_transf_34 PF05637.12 CRK18139.1 - 6.2e-18 65.4 0.2 1.1e-17 64.6 0.2 1.3 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family AviRa PF11599.8 CRK18140.1 - 0.05 13.1 0.1 0.053 13.0 0.1 1.0 1 0 0 1 1 1 0 RRNA methyltransferase AviRa Glyco_hydro_17 PF00332.18 CRK18141.1 - 0.053 13.1 0.2 0.075 12.6 0.2 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 Ammonium_transp PF00909.21 CRK18142.1 - 4.1e-112 374.8 26.9 4.7e-112 374.6 26.9 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family adh_short_C2 PF13561.6 CRK18143.1 - 3.2e-62 210.2 2.5 3.6e-62 210.0 2.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRK18143.1 - 2.6e-47 160.8 2.4 3e-47 160.6 2.4 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CRK18143.1 - 6.4e-13 49.0 2.4 9e-13 48.5 2.4 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CRK18143.1 - 0.017 14.6 0.3 0.027 13.9 0.3 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family HHH_5 PF14520.6 CRK18143.1 - 0.025 15.2 0.3 0.079 13.6 0.3 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain MDM31_MDM32 PF08118.11 CRK18143.1 - 0.06 12.0 0.0 0.063 11.9 0.0 1.1 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins Ldh_1_N PF00056.23 CRK18143.1 - 0.06 13.4 0.3 0.11 12.6 0.3 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain FAD-oxidase_C PF02913.19 CRK18144.1 - 2.6e-39 135.4 0.1 4e-39 134.7 0.1 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain MFS_1 PF07690.16 CRK18144.1 - 1.2e-33 116.6 28.9 1.8e-33 116.0 28.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily FAD_binding_4 PF01565.23 CRK18144.1 - 4.8e-16 58.7 0.0 1e-15 57.7 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain MFS_4 PF06779.14 CRK18144.1 - 1.8e-05 24.2 4.5 1.8e-05 24.2 4.5 2.5 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB Cnd1 PF12717.7 CRK18148.1 - 5.9e-46 156.5 0.1 6.5e-45 153.1 0.0 1.9 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 CRK18148.1 - 5.2e-31 107.8 0.2 6e-31 107.6 0.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT PF02985.22 CRK18148.1 - 5.1e-09 35.6 0.1 0.00073 19.6 0.0 3.5 3 0 0 3 3 3 2 HEAT repeat HEAT_2 PF13646.6 CRK18148.1 - 1.3e-06 28.7 0.7 7e-05 23.1 0.2 2.3 1 1 1 2 2 2 1 HEAT repeats HEAT_EZ PF13513.6 CRK18148.1 - 0.005 17.3 2.1 5.1 7.7 0.0 3.4 4 0 0 4 4 4 2 HEAT-like repeat RICTOR_N PF14664.6 CRK18148.1 - 0.014 14.4 0.6 1.4 7.8 0.2 2.1 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, N-term RTP1_C1 PF10363.9 CRK18148.1 - 0.042 14.0 0.3 1 9.6 0.3 2.5 1 1 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 CN_hydrolase PF00795.22 CRK18155.1 - 3.9e-41 141.1 0.0 4.4e-41 141.0 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NMO PF03060.15 CRK18156.1 - 2.9e-39 135.4 0.9 3.6e-39 135.1 0.9 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.18 CRK18156.1 - 2.4e-07 30.1 3.8 3e-07 29.8 3.8 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 CRK18156.1 - 0.0023 17.0 5.0 0.0029 16.7 5.0 1.2 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 CRK18156.1 - 0.0026 17.0 0.5 0.003 16.7 0.5 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.21 CRK18156.1 - 0.039 13.2 0.4 0.044 13.0 0.4 1.1 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Mito_carr PF00153.27 CRK18159.1 - 2.6e-22 78.6 0.0 2.5e-14 52.9 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein Mitoc_mL59 PF18126.1 CRK18161.1 - 7.3e-40 136.3 2.6 8e-40 136.1 2.6 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein mL59 UDPGP PF01704.18 CRK18162.1 - 6.7e-37 127.1 0.0 7.4e-37 127.0 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 CRK18162.1 - 0.1 13.0 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 MobA-like NTP transferase domain DUF2199 PF09965.9 CRK18168.1 - 0.036 14.1 0.0 0.045 13.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2199) DUF3584 PF12128.8 CRK18173.1 - 0.087 10.3 23.3 0.0053 14.4 14.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) TMF_DNA_bd PF12329.8 CRK18173.1 - 0.12 12.3 17.6 0.23 11.5 0.0 5.4 5 2 1 6 6 6 0 TATA element modulatory factor 1 DNA binding HIP1_clath_bdg PF16515.5 CRK18173.1 - 0.18 12.5 29.7 0.17 12.5 1.7 6.2 4 2 3 7 7 7 0 Clathrin-binding domain of Huntingtin-interacting protein 1 CENP-B_dimeris PF09026.10 CRK18173.1 - 0.76 10.2 13.8 0.47 10.9 11.0 2.0 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Fungal_trans_2 PF11951.8 CRK18173.1 - 1.1 8.0 2.7 0.46 9.2 0.1 1.6 2 0 0 2 2 2 0 Fungal specific transcription factor domain TFIIA PF03153.13 CRK18173.1 - 2 8.3 10.2 0.15 12.0 4.5 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Tropomyosin_1 PF12718.7 CRK18173.1 - 2.8 8.1 29.3 6.3 6.9 8.7 3.9 3 1 1 4 4 4 0 Tropomyosin like DUF1664 PF07889.12 CRK18173.1 - 3.2 7.8 12.2 11 6.1 0.2 4.7 3 1 3 6 6 6 0 Protein of unknown function (DUF1664) NOA36 PF06524.12 CRK18173.1 - 3.3 6.9 13.7 5.4 6.2 13.7 1.2 1 0 0 1 1 1 0 NOA36 protein RRN3 PF05327.11 CRK18173.1 - 4.2 5.8 10.8 9.3 4.6 10.8 1.5 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Baculo_PEP_C PF04513.12 CRK18173.1 - 5.9 6.9 11.8 0.51 10.4 0.1 4.0 4 1 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus PKcGMP_CC PF16808.5 CRK18173.1 - 6.5 6.7 7.8 11 6.0 0.5 3.7 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Fez1 PF06818.15 CRK18173.1 - 6.9 7.1 24.0 9.3 6.7 2.0 3.7 2 2 0 2 2 2 0 Fez1 Imm5 PF14423.6 CRK18173.1 - 8.9 6.5 11.3 0.55 10.4 5.2 2.1 2 0 0 2 2 2 0 Immunity protein Imm5 DUF5633 PF18656.1 CRK18174.1 - 0.19 11.6 0.1 0.32 10.9 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5633) Helo_like_N PF17111.5 CRK18175.1 - 0.00023 20.6 1.4 0.00036 19.9 0.1 2.0 1 1 2 3 3 3 1 Fungal N-terminal domain of STAND proteins Vma12 PF11712.8 CRK18176.1 - 2.9e-44 150.5 0.0 5.4e-44 149.6 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase zf-C2H2_3 PF13878.6 CRK18176.1 - 4.2e-08 32.9 0.4 7.5e-08 32.1 0.4 1.4 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO DUF1772 PF08592.11 CRK18176.1 - 0.057 13.7 0.4 0.11 12.8 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) polyprenyl_synt PF00348.17 CRK18177.1 - 1.2e-24 86.7 0.0 2e-24 86.0 0.0 1.3 1 0 0 1 1 1 1 Polyprenyl synthetase Amidohydro_1 PF01979.20 CRK18177.1 - 1.2e-08 34.7 0.0 3.2e-08 33.3 0.0 1.9 2 1 0 2 2 2 1 Amidohydrolase family Amidohydro_3 PF07969.11 CRK18177.1 - 1.8e-08 34.3 0.0 2.8e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family AalphaY_MDB PF04611.12 CRK18177.1 - 0.065 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Mating type protein A alpha Y mating type dependent binding region Flu_NP PF00506.18 CRK18177.1 - 0.076 11.7 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 Influenza virus nucleoprotein Glyco_hydro_3_C PF01915.22 CRK18178.1 - 7.3e-52 176.3 0.0 1.2e-51 175.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 CRK18178.1 - 5.2e-42 144.3 0.0 1.1e-41 143.3 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 CRK18178.1 - 1.4e-21 76.3 0.9 3.1e-21 75.2 0.9 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 CRK18178.1 - 5.6e-10 39.2 0.0 1.1e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 PA14 domain Sugar_tr PF00083.24 CRK18179.1 - 6.1e-84 282.5 21.6 7.4e-84 282.2 21.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK18179.1 - 9.4e-22 77.4 27.1 9.4e-22 77.4 27.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.18 CRK18181.1 - 4.3e-07 30.0 10.6 5.8e-07 29.5 10.6 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 CRK18181.1 - 1.1e-06 27.9 0.0 1.6e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pro_dh PF01619.18 CRK18182.1 - 1.8e-60 205.0 0.0 2.1e-60 204.7 0.0 1.1 1 0 0 1 1 1 1 Proline dehydrogenase Abhydrolase_1 PF00561.20 CRK18183.1 - 1.1e-23 84.2 0.0 4.2e-23 82.3 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 CRK18183.1 - 2.6e-20 72.4 0.2 2e-19 69.6 0.0 2.6 3 0 0 3 3 3 1 TAP-like protein BATS PF06968.13 CRK18184.1 - 3.2e-23 81.7 0.1 9.6e-23 80.1 0.1 1.9 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 CRK18184.1 - 1.5e-14 54.7 0.1 2.8e-14 53.8 0.1 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fungal_trans PF04082.18 CRK18185.1 - 7.3e-11 41.6 0.1 1.4e-10 40.7 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 CRK18186.1 - 4.1e-07 29.3 0.0 6.6e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK18186.1 - 0.00039 20.5 6.9 0.00075 19.6 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2OG-FeII_Oxy PF03171.20 CRK18187.1 - 9.7e-20 70.9 0.0 1.6e-19 70.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 CRK18187.1 - 1.9e-17 64.1 0.0 3.7e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Transp_cyt_pur PF02133.15 CRK18189.1 - 5.6e-84 282.4 26.6 6.4e-84 282.3 26.6 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin 2-Hacid_dh_C PF02826.19 CRK18191.1 - 3e-45 153.8 0.0 5.3e-45 153.0 0.0 1.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CRK18191.1 - 0.0001 22.0 0.0 0.00019 21.1 0.0 1.6 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.21 CRK18191.1 - 0.013 15.6 0.0 0.13 12.3 0.0 2.1 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_7 PF13241.6 CRK18191.1 - 0.016 15.6 0.0 0.076 13.5 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding ELFV_dehydrog PF00208.21 CRK18191.1 - 0.16 11.7 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase CytB6-F_Fe-S PF08802.10 CRK18193.1 - 0.0083 16.1 5.0 79 3.4 0.0 5.6 5 0 0 5 5 5 0 Cytochrome B6-F complex Fe-S subunit AA_kinase PF00696.28 CRK18193.1 - 0.03 13.9 0.1 40 3.7 0.0 3.4 1 1 3 4 4 4 0 Amino acid kinase family Collagen_mid PF15984.5 CRK18193.1 - 0.13 12.0 14.1 41 3.8 4.2 5.1 1 1 1 2 2 2 0 Bacterial collagen, middle region DUF3645 PF12359.8 CRK18193.1 - 1.2 8.6 3.4 2e+02 1.5 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3645) Glyco_hydro_61 PF03443.14 CRK18194.1 - 2.1e-53 181.3 0.0 2.5e-53 181.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 EHN PF06441.12 CRK18195.1 - 1.5e-37 128.2 0.8 1.2e-35 122.1 0.0 2.3 2 0 0 2 2 2 2 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 CRK18195.1 - 4.6e-11 42.9 0.1 7.1e-11 42.2 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CRK18195.1 - 0.0026 18.4 6.8 0.0026 18.4 6.8 1.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family MFS_1 PF07690.16 CRK18199.1 - 1.1e-22 80.4 11.1 1.5e-22 80.1 11.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily HTH_57 PF18679.1 CRK18201.1 - 0.059 13.7 0.0 0.21 11.9 0.0 1.9 1 0 0 1 1 1 0 ThcOx helix turn helix domain FMN_dh PF01070.18 CRK18203.1 - 2.1e-83 280.3 0.0 1.2e-49 169.3 0.0 2.0 1 1 1 2 2 2 2 FMN-dependent dehydrogenase IMPDH PF00478.25 CRK18203.1 - 2.2e-06 27.0 0.2 2.7e-05 23.4 0.0 2.3 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 CRK18203.1 - 0.00046 19.4 0.1 0.0011 18.2 0.1 1.6 1 1 0 1 1 1 1 Conserved region in glutamate synthase Peptidase_M19 PF01244.21 CRK18203.1 - 0.0042 16.3 0.0 0.035 13.3 0.0 2.1 1 1 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) NMO PF03060.15 CRK18203.1 - 0.012 15.0 0.1 0.016 14.6 0.1 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase Pec_lyase_C PF00544.19 CRK18205.1 - 7.2e-12 45.3 8.6 3.2e-10 40.0 8.6 2.2 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 CRK18205.1 - 5.3e-06 26.4 14.3 0.0022 17.8 7.8 2.5 1 1 1 2 2 2 2 Right handed beta helix region Phage_attach PF05354.11 CRK18205.1 - 0.046 13.6 0.1 0.37 10.7 0.1 2.3 2 0 0 2 2 2 0 Phage Head-Tail Attachment Ferric_reduct PF01794.19 CRK18207.1 - 5.4e-17 62.1 10.7 5.4e-17 62.1 10.7 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 CRK18207.1 - 3.6e-05 23.8 0.0 0.42 10.7 0.0 3.1 3 0 0 3 3 3 2 FAD-binding domain NAD_binding_6 PF08030.12 CRK18207.1 - 3.8e-05 23.9 0.0 0.076 13.1 0.0 2.4 1 1 1 2 2 2 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 CRK18207.1 - 0.22 12.2 0.0 2.7 8.7 0.0 2.3 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain IMUP PF15761.5 CRK18207.1 - 0.83 10.4 16.2 0.11 13.3 8.3 2.3 2 0 0 2 2 2 0 Immortalisation up-regulated protein Secretin_N_2 PF07655.13 CRK18207.1 - 4.8 7.8 9.0 1 10.0 1.7 2.3 2 0 0 2 2 2 0 Secretin N-terminal domain Peptidase_M14 PF00246.24 CRK18209.1 - 5.9e-68 229.8 0.0 7.1e-68 229.5 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Pec_lyase_C PF00544.19 CRK18211.1 - 1.5e-21 77.0 6.7 1.5e-20 73.7 6.7 2.1 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 CRK18211.1 - 1.1e-05 25.3 8.1 2.5e-05 24.2 8.1 1.6 1 0 0 1 1 1 1 Right handed beta helix region Pectate_lyase_3 PF12708.7 CRK18211.1 - 0.019 14.8 4.9 0.033 14.0 4.9 1.3 1 0 0 1 1 1 0 Pectate lyase superfamily protein Ecm33 PF12454.8 CRK18211.1 - 2.1 8.5 5.5 1.1 9.5 0.4 2.7 2 1 0 2 2 2 0 GPI-anchored cell wall organization protein Peptidase_M28 PF04389.17 CRK18216.1 - 7.9e-39 133.4 0.0 1.2e-38 132.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 CRK18216.1 - 1.4e-10 41.1 0.1 2.8e-10 40.1 0.1 1.5 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 CRK18216.1 - 0.019 14.7 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Sulfotransfer_3 PF13469.6 CRK18236.1 - 3.6e-07 30.8 0.0 6.9e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase family Mhr1 PF12829.7 CRK18237.1 - 3.8e-07 30.1 0.0 6.3e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination RabGAP-TBC PF00566.18 CRK18238.1 - 1.5e-11 44.4 0.6 2.2e-11 43.9 0.6 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Herpes_UL7 PF01677.16 CRK18238.1 - 0.048 13.4 0.0 0.061 13.0 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL7 like RNA_pol_Rpb4 PF03874.16 CRK18238.1 - 0.17 12.2 0.1 0.36 11.2 0.1 1.6 1 1 1 2 2 2 0 RNA polymerase Rpb4 ERM PF00769.19 CRK18241.1 - 0.03 14.1 19.9 0.032 14.0 19.9 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family UPF0172 PF03665.13 CRK18241.1 - 0.12 12.4 7.0 0.2 11.7 6.2 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) DDRGK PF09756.9 CRK18241.1 - 0.19 11.3 18.4 0.25 10.9 18.4 1.1 1 0 0 1 1 1 0 DDRGK domain ActA PF05058.12 CRK18241.1 - 0.38 9.1 8.5 0.51 8.6 8.5 1.1 1 0 0 1 1 1 0 ActA Protein Presenilin PF01080.17 CRK18241.1 - 5.4 5.7 6.9 5.6 5.6 6.9 1.1 1 0 0 1 1 1 0 Presenilin UCH PF00443.29 CRK18246.1 - 8.2e-13 48.4 0.3 1.1e-12 48.0 0.3 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MatE PF01554.18 CRK18252.1 - 2e-09 37.3 2.2 2.4e-09 37.1 2.2 1.1 1 0 0 1 1 1 1 MatE ABC2_membrane PF01061.24 CRK18254.1 - 8.1e-33 113.6 15.2 1.1e-32 113.2 15.2 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 CRK18254.1 - 7.7e-21 75.0 0.0 1.3e-20 74.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CRK18254.1 - 1.7e-05 24.8 0.0 0.11 12.3 0.0 3.0 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 CRK18254.1 - 0.00011 22.6 0.0 0.00019 21.8 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 CRK18254.1 - 0.00094 19.1 0.0 0.0017 18.3 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 CRK18254.1 - 0.012 15.3 0.1 0.029 14.1 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.19 CRK18254.1 - 0.013 14.9 0.0 0.33 10.4 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 CRK18254.1 - 0.04 13.5 0.0 0.078 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CRK18254.1 - 0.088 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 CRK18254.1 - 0.099 12.6 0.1 0.21 11.6 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 CRK18254.1 - 0.1 12.9 0.1 0.21 11.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CRK18254.1 - 0.12 12.6 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CRK18254.1 - 0.17 11.6 0.1 0.34 10.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain SET PF00856.28 CRK18255.1 - 7.1e-23 81.8 0.6 1.2e-12 48.5 0.1 3.1 2 1 0 2 2 2 2 SET domain SAF PF08666.12 CRK18255.1 - 5.7e-05 23.7 0.3 0.47 11.1 0.0 3.5 3 0 0 3 3 3 1 SAF domain TPR_2 PF07719.17 CRK18255.1 - 0.00032 20.6 3.3 0.096 12.8 0.7 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 CRK18255.1 - 0.18 11.7 0.6 0.77 9.7 0.3 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 CRK18255.1 - 7.6 6.3 10.2 9.2 6.0 0.5 4.1 4 0 0 4 4 4 0 TPR repeat Retrotran_gag_3 PF14244.6 CRK18255.1 - 7.9 6.4 7.3 8 6.4 0.2 3.3 3 0 0 3 3 3 0 gag-polypeptide of LTR copia-type Sugar_tr PF00083.24 CRK18259.1 - 2.7e-94 316.6 23.3 3.1e-94 316.4 23.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK18259.1 - 4.7e-31 108.0 28.2 8.8e-31 107.1 24.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CRK18259.1 - 1.2e-06 27.2 13.9 2.9e-05 22.7 3.3 2.3 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) APH PF01636.23 CRK18260.1 - 5e-16 59.4 0.6 5e-16 59.4 0.6 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 CRK18260.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 RIO1 family adh_short_C2 PF13561.6 CRK18262.1 - 1.7e-30 106.3 0.8 8.5e-30 104.0 0.8 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRK18262.1 - 2.6e-22 79.3 0.4 2.8e-21 75.9 0.4 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CRK18262.1 - 1.2e-05 25.3 0.1 2e-05 24.6 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CRK18262.1 - 0.13 11.7 0.3 1.5 8.3 0.3 2.2 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Acetyltransf_1 PF00583.25 CRK18263.1 - 2.1e-08 34.4 0.0 2.8e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CRK18263.1 - 8.5e-06 25.7 0.0 1.2e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CRK18263.1 - 0.00018 21.9 0.0 0.00027 21.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CRK18263.1 - 0.0033 17.4 0.0 0.0054 16.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein FAD_binding_4 PF01565.23 CRK18264.1 - 1.5e-22 79.8 0.5 2.5e-22 79.1 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain Complex1_LYR PF05347.15 CRK18265.1 - 9.5e-21 73.6 0.0 1.4e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 CRK18265.1 - 9.6e-06 26.3 0.0 1.4e-05 25.8 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Ribosomal_L36 PF00444.18 CRK18266.1 - 7.4e-22 77.3 11.3 1e-21 76.8 11.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L36 Ribosomal_L35p PF01632.19 CRK18266.1 - 0.091 13.3 5.1 0.28 11.7 5.1 1.9 1 1 0 1 1 1 0 Ribosomal protein L35 PALP PF00291.25 CRK18268.1 - 2.7e-77 260.1 0.5 3.4e-77 259.7 0.5 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 CRK18268.1 - 5.2e-41 138.3 0.0 1.1e-21 76.3 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase TLD PF07534.16 CRK18269.1 - 1.8e-26 93.0 0.0 3.3e-26 92.2 0.0 1.4 1 0 0 1 1 1 1 TLD DUF1773 PF08593.10 CRK18269.1 - 7.9e-17 62.0 0.4 2.5e-16 60.4 0.4 1.9 1 0 0 1 1 1 1 Domain of unknown function HeLo PF14479.6 CRK18271.1 - 2.4e-08 34.1 0.7 4.8e-06 26.6 0.5 2.2 1 1 1 2 2 2 2 Prion-inhibition and propagation Pkinase PF00069.25 CRK18271.1 - 0.0014 18.1 0.0 0.0026 17.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK18271.1 - 0.012 14.9 0.0 0.027 13.7 0.0 1.5 1 1 0 1 1 1 0 Protein tyrosine kinase NMT_C PF02799.15 CRK18273.1 - 1.9e-83 279.1 0.0 3.2e-83 278.4 0.0 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 CRK18273.1 - 6.2e-71 237.4 0.5 1.3e-70 236.3 0.0 1.7 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Abhydrolase_6 PF12697.7 CRK18273.1 - 5.3e-10 40.3 3.9 1.3e-09 39.0 3.9 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CRK18273.1 - 2.1e-09 37.0 0.3 1.9e-08 33.8 0.1 2.2 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CRK18273.1 - 4e-08 33.2 0.1 9.6e-08 32.0 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Acetyltransf_9 PF13527.7 CRK18273.1 - 1.6e-05 25.0 0.2 0.00043 20.4 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CRK18273.1 - 0.00042 20.5 0.0 0.0054 17.0 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Abhydrolase_3 PF07859.13 CRK18273.1 - 0.0011 18.9 0.1 0.002 18.0 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 CRK18273.1 - 0.0029 17.2 0.1 0.0071 16.0 0.1 1.6 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Coilin_N PF15862.5 CRK18273.1 - 0.013 15.3 0.0 0.069 12.9 0.0 2.1 2 1 0 2 2 2 0 Coilin N-terminus PGA2 PF07543.12 CRK18273.1 - 0.11 12.5 7.6 0.22 11.5 7.6 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 Thioesterase PF00975.20 CRK18273.1 - 0.16 12.0 0.0 0.49 10.5 0.0 1.8 1 1 0 1 1 1 0 Thioesterase domain TFIIF_alpha PF05793.12 CRK18273.1 - 0.37 9.3 12.4 0.55 8.8 12.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) LZ_Tnp_IS66 PF13007.7 CRK18273.1 - 0.76 10.6 4.3 2.1 9.2 4.3 1.7 1 0 0 1 1 1 0 Transposase C of IS166 homeodomain Abhydrolase_1 PF00561.20 CRK18274.1 - 1.1e-10 41.7 0.0 9.1e-10 38.6 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CRK18274.1 - 9e-09 36.3 0.1 1.1e-08 36.0 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CRK18274.1 - 1.9e-08 33.9 0.0 7.4e-08 31.9 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 CRK18274.1 - 0.13 12.4 0.0 0.32 11.1 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein EF-hand_1 PF00036.32 CRK18275.1 - 2.6e-11 42.2 7.5 2e-05 23.8 0.2 3.7 3 0 0 3 3 3 2 EF hand ZZ PF00569.17 CRK18275.1 - 5.5e-10 38.9 7.4 9.4e-10 38.2 7.4 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_6 PF13405.6 CRK18275.1 - 1.4e-08 34.0 6.1 0.00022 20.9 0.3 3.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 CRK18275.1 - 1.9e-05 25.0 12.7 0.0011 19.3 0.5 4.2 3 1 0 4 4 4 2 EF-hand domain pair EF-hand_8 PF13833.6 CRK18275.1 - 0.00032 20.5 2.8 0.61 10.0 0.1 3.5 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_4 PF12763.7 CRK18275.1 - 0.061 13.3 0.4 0.3 11.0 0.0 2.4 2 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.6 CRK18275.1 - 0.12 11.9 8.2 0.54 9.9 0.3 3.6 3 0 0 3 3 3 0 EF hand Dockerin_1 PF00404.18 CRK18275.1 - 0.14 12.4 0.3 0.48 10.7 0.0 2.0 2 0 0 2 2 2 0 Dockerin type I domain C1_2 PF03107.16 CRK18275.1 - 0.51 10.7 9.2 0.93 9.9 9.2 1.4 1 0 0 1 1 1 0 C1 domain CC190 PF15768.5 CRK18275.1 - 6.4 6.8 9.3 2.5 8.1 1.6 2.9 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 190 GATA PF00320.27 CRK18276.1 - 3.5e-13 48.9 2.0 3.5e-13 48.9 2.0 2.3 2 0 0 2 2 2 1 GATA zinc finger DZR PF12773.7 CRK18276.1 - 0.011 15.8 0.3 0.024 14.7 0.3 1.5 1 0 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 CRK18276.1 - 0.024 14.7 0.3 0.057 13.6 0.3 1.6 1 0 0 1 1 1 0 Zinc ribbon domain zf-Sec23_Sec24 PF04810.15 CRK18276.1 - 0.14 12.2 0.1 0.26 11.4 0.1 1.4 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger zf-C2H2_3 PF13878.6 CRK18276.1 - 0.2 11.5 0.8 1.8 8.5 0.0 2.3 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO Cellulase PF00150.18 CRK18277.1 - 9.6e-22 77.7 1.6 1.4e-21 77.2 1.6 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 CRK18277.1 - 1.1e-13 50.9 15.6 3.5e-13 49.3 15.6 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain Glyco_hydro_42 PF02449.15 CRK18277.1 - 0.0006 19.3 0.1 0.00099 18.5 0.1 1.3 1 0 0 1 1 1 1 Beta-galactosidase Glyco_hydro_2_C PF02836.17 CRK18277.1 - 0.065 12.3 0.0 0.099 11.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain AP_endonuc_2 PF01261.24 CRK18277.1 - 0.11 11.9 0.0 0.32 10.4 0.0 1.7 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel MGC-24 PF05283.11 CRK18277.1 - 1.3 9.4 11.1 3.2 8.2 11.1 1.6 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin adh_short_C2 PF13561.6 CRK18279.1 - 2.2e-58 197.6 0.8 2.6e-58 197.3 0.8 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRK18279.1 - 7.7e-49 165.8 0.8 9.4e-49 165.5 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CRK18279.1 - 3.9e-13 49.7 0.5 5.9e-13 49.1 0.5 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CRK18279.1 - 0.0051 16.3 0.5 0.012 15.0 0.5 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CRK18279.1 - 0.0073 15.7 0.0 0.017 14.5 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase ABC2_membrane PF01061.24 CRK18280.1 - 3e-93 311.0 49.5 7.3e-48 162.8 21.0 2.7 2 0 0 2 2 2 2 ABC-2 type transporter PDR_CDR PF06422.12 CRK18280.1 - 9.2e-38 128.0 0.3 4.5e-33 113.0 0.1 3.1 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.27 CRK18280.1 - 1.1e-27 97.2 0.0 1.8e-15 57.7 0.0 3.0 3 0 0 3 3 3 2 ABC transporter ABC_trans_N PF14510.6 CRK18280.1 - 8.6e-14 51.9 0.0 3e-13 50.2 0.0 2.0 1 0 0 1 1 1 1 ABC-transporter N-terminal Fungal_trans_2 PF11951.8 CRK18280.1 - 1.8e-08 33.6 0.0 5.9e-08 31.9 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain AAA_25 PF13481.6 CRK18280.1 - 6.2e-06 25.9 0.0 0.00015 21.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CRK18280.1 - 2e-05 24.8 0.2 0.37 11.0 0.0 2.9 3 0 0 3 3 2 2 AAA domain RsgA_GTPase PF03193.16 CRK18280.1 - 4.5e-05 23.4 0.0 0.0036 17.2 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 CRK18280.1 - 8.3e-05 23.0 0.0 0.044 14.2 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 CRK18280.1 - 0.00026 21.6 0.0 0.12 12.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CRK18280.1 - 0.0004 20.0 0.5 0.048 13.4 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.7 CRK18280.1 - 0.00074 18.7 6.0 0.00074 18.7 6.0 3.1 2 2 0 2 2 2 1 ABC-2 family transporter protein NACHT PF05729.12 CRK18280.1 - 0.0034 17.3 0.1 3.3 7.6 0.1 2.7 2 0 0 2 2 2 2 NACHT domain AAA_22 PF13401.6 CRK18280.1 - 0.0046 17.2 0.1 1.1 9.5 0.1 2.5 2 0 0 2 2 2 1 AAA domain PDR_assoc PF08370.11 CRK18280.1 - 0.0093 15.7 0.6 1.5 8.6 0.0 3.3 3 0 0 3 3 3 1 Plant PDR ABC transporter associated cobW PF02492.19 CRK18280.1 - 0.0097 15.5 0.5 0.12 11.9 0.1 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 CRK18280.1 - 0.011 16.2 0.1 5 7.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain Zn_clus PF00172.18 CRK18280.1 - 0.023 14.8 8.8 0.045 13.9 8.8 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA PF00004.29 CRK18280.1 - 0.038 14.4 0.0 5.3 7.5 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 CRK18280.1 - 0.08 13.4 0.0 0.21 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 CRK18280.1 - 0.13 12.1 0.0 2 8.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 CRK18280.1 - 0.16 11.6 0.2 8.8 6.0 0.1 2.3 2 0 0 2 2 2 0 AAA domain DUF1440 PF07274.12 CRK18280.1 - 2.3 8.5 5.3 5.3 7.4 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1440) OSCP PF00213.18 CRK18281.1 - 0.056 13.6 0.0 0.098 12.8 0.0 1.3 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit Glyco_hydro_43 PF04616.14 CRK18282.1 - 1.8e-53 181.7 1.4 2.5e-53 181.3 1.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 CRK18282.1 - 3.3e-31 108.6 0.0 6.6e-31 107.6 0.0 1.4 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain DUF5005 PF16396.5 CRK18282.1 - 0.008 14.9 0.1 0.13 10.9 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF5005) HET PF06985.11 CRK18283.1 - 2.2e-33 115.7 0.1 3.6e-33 115.0 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) p450 PF00067.22 CRK18284.1 - 4.2e-30 104.9 0.1 6.1e-30 104.4 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 LysM PF01476.20 CRK18284.1 - 2.1e-14 53.3 0.0 2.1e-06 27.7 0.0 2.5 2 0 0 2 2 2 2 LysM domain DUF903 PF06004.12 CRK18284.1 - 0.071 13.0 0.5 0.17 11.8 0.5 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF903) Lectin_N PF03954.14 CRK18286.1 - 0.021 14.5 2.5 0.17 11.6 2.5 2.3 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain FMO-like PF00743.19 CRK18288.1 - 8.7e-12 44.2 0.0 1.6e-08 33.5 0.1 3.1 2 2 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 CRK18288.1 - 9.8e-10 38.5 0.0 2e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 CRK18288.1 - 9.3e-06 25.1 0.0 6.1e-05 22.4 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CRK18288.1 - 0.00058 19.5 0.0 0.27 10.8 0.0 3.0 2 1 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 CRK18288.1 - 0.0013 18.0 0.0 0.0028 16.9 0.0 1.5 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 CRK18288.1 - 0.0047 16.9 0.0 0.024 14.6 0.0 2.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 CRK18288.1 - 0.014 14.6 0.0 9 5.3 0.0 3.1 3 1 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 CRK18288.1 - 0.15 10.7 0.0 0.24 10.1 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein AMP-binding PF00501.28 CRK18289.1 - 2e-93 313.3 0.0 2.8e-93 312.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CRK18289.1 - 4.2e-10 40.5 1.9 1.6e-09 38.6 1.6 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain adh_short_C2 PF13561.6 CRK18292.1 - 8.2e-43 146.6 0.1 9.9e-43 146.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRK18292.1 - 1.2e-34 119.4 0.1 2.1e-34 118.7 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CRK18292.1 - 8.9e-08 32.2 0.3 1.5e-07 31.5 0.3 1.3 1 1 0 1 1 1 1 KR domain Tex_YqgF PF16921.5 CRK18292.1 - 0.023 15.2 0.0 6.6 7.2 0.0 2.2 2 0 0 2 2 2 0 Tex protein YqgF-like domain Polysacc_synt_2 PF02719.15 CRK18292.1 - 0.14 11.3 0.1 0.21 10.7 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ADH_zinc_N PF00107.26 CRK18293.1 - 8.2e-21 74.3 1.4 2e-20 73.1 0.3 2.1 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CRK18293.1 - 2e-16 59.8 0.2 3.4e-16 59.1 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain 2-Hacid_dh_C PF02826.19 CRK18293.1 - 0.00063 19.2 0.0 0.0013 18.1 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 CRK18293.1 - 0.0015 17.8 0.1 0.0026 17.1 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_25 PF13649.6 CRK18293.1 - 0.0092 16.7 0.1 0.021 15.5 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 CRK18293.1 - 0.016 16.3 0.0 0.03 15.4 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase TrkA_N PF02254.18 CRK18293.1 - 0.019 15.2 0.0 0.049 13.9 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Methyltransf_11 PF08241.12 CRK18293.1 - 0.038 14.6 0.1 0.085 13.5 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain 3HCDH_N PF02737.18 CRK18293.1 - 0.052 13.4 1.6 0.095 12.6 0.5 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CMAS PF02353.20 CRK18293.1 - 0.13 11.6 0.1 0.2 10.9 0.1 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Aldedh PF00171.22 CRK18295.1 - 3.4e-155 517.1 0.1 3.9e-155 516.9 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 CRK18295.1 - 0.0025 16.9 0.0 0.0042 16.2 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) NACHT_N PF17100.5 CRK18297.1 - 8.2e-41 140.3 2.9 2e-40 139.0 2.9 1.7 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase Ank_2 PF12796.7 CRK18297.1 - 1.1e-11 45.2 0.2 4.6e-05 23.9 0.1 4.2 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CRK18297.1 - 3.1e-11 43.3 0.4 4.8e-08 33.1 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 CRK18297.1 - 4.4e-11 43.1 0.6 2.1e-06 28.2 0.0 4.6 2 2 2 4 4 4 2 Ankyrin repeats (many copies) NACHT PF05729.12 CRK18297.1 - 9.2e-09 35.4 0.0 2.7e-08 33.9 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 CRK18297.1 - 1.9e-06 28.2 2.5 3.6e-06 27.3 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 CRK18297.1 - 5.3e-06 26.9 1.2 1.4e-05 25.6 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain Ank_3 PF13606.6 CRK18297.1 - 3.2e-05 24.0 0.0 0.036 14.6 0.0 4.6 4 0 0 4 4 3 1 Ankyrin repeat Ank PF00023.30 CRK18297.1 - 0.00021 21.6 2.2 0.1 13.1 0.0 4.4 4 0 0 4 4 4 1 Ankyrin repeat KAP_NTPase PF07693.14 CRK18297.1 - 0.0051 16.1 0.0 0.56 9.4 0.1 2.5 1 1 1 2 2 2 1 KAP family P-loop domain AAA_25 PF13481.6 CRK18297.1 - 0.0068 16.0 0.0 0.023 14.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CRK18297.1 - 0.079 13.0 0.0 0.51 10.4 0.0 2.6 2 1 0 2 2 1 0 AAA domain FUSC PF04632.12 CRK18297.1 - 7.4 5.0 6.8 16 3.9 6.8 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein family SPX PF03105.19 CRK18326.1 - 7.7e-24 85.3 5.4 1e-23 84.9 5.4 1.2 1 0 0 1 1 1 1 SPX domain EXS PF03124.14 CRK18326.1 - 0.00053 19.4 2.1 0.00071 19.0 2.1 1.2 1 0 0 1 1 1 1 EXS family DUF418 PF04235.12 CRK18326.1 - 0.011 15.7 0.1 0.014 15.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF418) GCR1_C PF12550.8 CRK18326.1 - 0.021 15.1 0.1 0.31 11.4 0.0 2.2 1 1 1 2 2 2 0 Transcriptional activator of glycolytic enzymes FUR PF01475.19 CRK18326.1 - 0.17 12.1 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Ferric uptake regulator family ILVD_EDD PF00920.21 CRK18359.1 - 1e-38 133.3 0.5 1.1e-38 133.2 0.5 1.0 1 0 0 1 1 1 1 Dehydratase family Uricase PF01014.18 CRK18373.1 - 1.1e-46 158.3 0.2 1e-31 109.9 0.1 2.0 2 0 0 2 2 2 2 Uricase adh_short_C2 PF13561.6 CRK18384.1 - 8.7e-42 143.3 0.0 9.5e-42 143.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRK18384.1 - 3e-26 92.1 0.0 4.3e-26 91.6 0.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase DUF1776 PF08643.10 CRK18384.1 - 0.015 14.7 0.0 0.02 14.3 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) adh_short PF00106.25 CRK18385.1 - 2.5e-21 76.0 0.0 2.8e-21 75.9 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK18385.1 - 8.6e-15 54.9 0.0 9.2e-15 54.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK18385.1 - 0.0012 18.7 0.0 0.0014 18.6 0.0 1.0 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CRK18385.1 - 0.0023 17.4 0.0 0.012 15.0 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 CRK18385.1 - 0.12 11.7 0.0 0.13 11.6 0.0 1.0 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DUF819 PF05684.12 CRK18412.1 - 0.069 12.2 5.1 0.042 12.9 3.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF819) tRNA_anti-codon PF01336.25 CRK18413.1 - 8.7e-08 32.1 0.0 1.4e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti-like PF12869.7 CRK18413.1 - 0.03 13.9 0.0 0.041 13.5 0.0 1.2 1 0 0 1 1 1 0 tRNA_anti-like NUDIX PF00293.28 CRK18425.1 - 1.9e-16 60.3 1.2 2.3e-16 60.0 1.2 1.1 1 0 0 1 1 1 1 NUDIX domain DUF4691 PF15762.5 CRK18425.1 - 0.034 14.3 0.1 0.073 13.2 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4691) LSM PF01423.22 CRK18426.1 - 1.1e-09 37.9 0.0 0.00027 20.5 0.0 2.3 2 0 0 2 2 2 2 LSM domain Arm-DNA-bind_3 PF13356.6 CRK18426.1 - 0.056 13.8 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 Arm DNA-binding domain Glyco_hyd_65N_2 PF14498.6 CRK18427.1 - 0.026 14.4 0.0 0.045 13.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Mob1_phocein PF03637.17 CRK18428.1 - 2.6e-68 229.3 0.1 4e-68 228.7 0.1 1.2 1 0 0 1 1 1 1 Mob1/phocein family OSCP PF00213.18 CRK18428.1 - 9.9e-45 152.7 2.8 1.4e-44 152.2 2.8 1.2 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit DUF1993 PF09351.10 CRK18428.1 - 0.018 15.2 0.5 0.067 13.3 0.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1993) Glyco_hydro_63 PF03200.16 CRK18429.1 - 9.2e-08 31.3 8.9 2e-06 26.9 0.1 4.2 5 1 0 5 5 5 2 Glycosyl hydrolase family 63 C-terminal domain Hep_59 PF07052.11 CRK18429.1 - 0.031 15.0 0.5 0.062 14.1 0.5 1.5 1 0 0 1 1 1 0 Hepatocellular carcinoma-associated antigen 59 RasGEF PF00617.19 CRK18430.1 - 4.8e-24 85.5 0.0 5.9e-24 85.2 0.0 1.1 1 0 0 1 1 1 1 RasGEF domain RasGEF PF00617.19 CRK18431.1 - 6.5e-47 160.0 0.0 1e-46 159.3 0.0 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 CRK18431.1 - 2.8e-12 46.8 0.0 6.1e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif Ras PF00071.22 CRK18431.1 - 1e-05 25.2 0.1 0.0004 20.0 0.0 2.5 3 0 0 3 3 3 1 Ras family MMR_HSR1 PF01926.23 CRK18431.1 - 0.0084 16.2 0.0 0.02 15.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CRK18431.1 - 0.011 15.3 0.0 0.18 11.3 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CRK18431.1 - 0.064 13.1 0.0 2.1 8.2 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase Roc PF08477.13 CRK18431.1 - 0.089 13.0 0.0 0.21 11.8 0.0 1.7 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CRK18432.1 - 5.1e-06 26.2 0.0 0.001 18.7 0.0 2.1 2 0 0 2 2 2 2 Ras family MMR_HSR1 PF01926.23 CRK18432.1 - 0.00012 22.2 0.0 0.00023 21.2 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CRK18432.1 - 0.00012 21.6 0.0 0.017 14.7 0.0 2.0 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Roc PF08477.13 CRK18432.1 - 0.00028 21.1 0.0 0.00082 19.6 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 CRK18432.1 - 0.0012 18.8 0.0 0.16 11.9 0.2 2.4 2 1 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 CRK18432.1 - 0.025 14.9 0.1 0.083 13.2 0.1 2.0 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CRK18432.1 - 0.031 14.8 0.0 0.032 14.8 0.0 1.2 1 0 0 1 1 1 0 ABC transporter IIGP PF05049.13 CRK18432.1 - 0.038 13.0 0.0 0.049 12.7 0.0 1.1 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) ATP_bind_1 PF03029.17 CRK18432.1 - 0.049 13.4 0.0 2.6 7.8 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.18 CRK18432.1 - 0.082 12.3 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.6 CRK18432.1 - 0.1 12.4 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 CRK18432.1 - 0.12 12.7 0.0 0.12 12.7 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 CRK18432.1 - 0.14 11.6 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region TFIIA PF03153.13 CRK18434.1 - 1 9.3 8.0 1.2 9.0 8.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-HIT PF04438.16 CRK18436.1 - 4.6e-09 36.0 10.5 6.2e-09 35.6 10.5 1.2 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 CRK18436.1 - 0.0045 17.1 5.0 0.0082 16.2 5.0 1.4 1 0 0 1 1 1 1 MYND finger zf-B_box PF00643.24 CRK18436.1 - 0.011 15.9 5.0 0.017 15.3 5.0 1.3 1 0 0 1 1 1 0 B-box zinc finger Nfu_N PF08712.11 CRK18438.1 - 5.9e-28 96.7 0.0 1.4e-27 95.5 0.0 1.7 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 CRK18438.1 - 6.8e-28 96.6 0.1 1.1e-27 95.9 0.1 1.3 1 0 0 1 1 1 1 NifU-like domain YojJ PF10372.9 CRK18438.1 - 0.16 12.1 0.1 0.3 11.2 0.1 1.4 1 0 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus zf-HIT PF04438.16 CRK18440.1 - 1.6e-08 34.3 10.1 2.2e-08 33.8 10.1 1.2 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 CRK18440.1 - 0.0019 18.3 4.4 0.0026 17.8 4.4 1.2 1 0 0 1 1 1 1 MYND finger zf-B_box PF00643.24 CRK18440.1 - 0.0033 17.5 4.8 0.0048 17.0 4.8 1.2 1 0 0 1 1 1 1 B-box zinc finger Nfu_N PF08712.11 CRK18441.1 - 5.8e-28 96.8 0.0 1.4e-27 95.5 0.0 1.7 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 CRK18441.1 - 6.9e-28 96.6 0.1 1.1e-27 95.9 0.1 1.3 1 0 0 1 1 1 1 NifU-like domain YojJ PF10372.9 CRK18441.1 - 0.15 12.1 0.1 0.3 11.2 0.1 1.4 1 0 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus CHZ PF09649.10 CRK18443.1 - 1.9e-18 65.6 2.1 1.9e-18 65.6 2.1 1.8 2 0 0 2 2 2 1 Histone chaperone domain CHZ GP24_25 PF17388.2 CRK18443.1 - 0.1 12.6 1.1 0.13 12.2 0.5 1.5 1 1 0 1 1 1 0 Tail assembly gene products 24 & 25 Use1 PF09753.9 CRK18444.1 - 0.008 15.9 0.0 0.011 15.5 0.0 1.1 1 0 0 1 1 1 1 Membrane fusion protein Use1 Apc15p PF05841.11 CRK18445.1 - 6.9e-21 75.3 1.4 8e-20 71.9 1.4 2.3 1 1 0 1 1 1 1 Apc15p protein Glu_synthase PF01645.17 CRK18446.1 - 5.1e-155 516.1 0.0 7.9e-155 515.5 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase GATase_2 PF00310.21 CRK18446.1 - 3.4e-110 368.7 0.0 5.1e-110 368.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.14 CRK18446.1 - 9.2e-110 366.5 0.0 2.1e-108 362.0 0.0 2.2 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 CRK18446.1 - 3e-86 287.9 2.9 4.6e-86 287.3 2.9 1.3 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 CRK18446.1 - 2.4e-21 76.2 0.0 2.6e-20 72.9 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 CRK18446.1 - 3.1e-21 75.2 0.1 6.6e-21 74.2 0.1 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 CRK18446.1 - 8.2e-08 32.4 0.0 2.8e-07 30.7 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CRK18446.1 - 8.4e-07 28.9 0.3 0.00068 19.3 0.1 2.7 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 CRK18446.1 - 6.7e-06 26.6 0.0 0.0057 17.2 0.0 2.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 CRK18446.1 - 1.3e-05 24.7 0.1 2.4e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 CRK18446.1 - 0.00024 20.5 1.6 0.27 10.5 0.2 3.6 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CRK18446.1 - 0.00046 19.0 1.6 0.00051 18.9 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 CRK18446.1 - 0.0013 18.2 0.1 0.0013 18.2 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 CRK18446.1 - 0.0062 15.8 0.0 0.013 14.7 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 CRK18446.1 - 0.0073 15.4 0.0 0.0073 15.4 0.0 2.1 3 0 0 3 3 2 1 FAD binding domain Thi4 PF01946.17 CRK18446.1 - 0.02 14.1 1.8 0.028 13.7 0.1 2.0 2 0 0 2 2 2 0 Thi4 family AlaDh_PNT_C PF01262.21 CRK18446.1 - 0.021 14.1 0.0 1.9 7.7 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FMN_dh PF01070.18 CRK18446.1 - 0.021 13.8 0.9 0.17 10.9 0.8 2.3 3 0 0 3 3 3 0 FMN-dependent dehydrogenase NAD_binding_7 PF13241.6 CRK18446.1 - 0.075 13.5 0.4 11 6.5 0.0 2.7 2 0 0 2 2 2 0 Putative NAD(P)-binding Lycopene_cycl PF05834.12 CRK18446.1 - 0.14 11.2 0.3 1.4 7.9 0.1 2.6 4 0 0 4 4 4 0 Lycopene cyclase protein GIDA PF01134.22 CRK18446.1 - 0.19 10.7 1.4 0.76 8.8 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A FMO-like PF00743.19 CRK18446.1 - 0.23 9.8 0.0 34 2.7 0.0 2.9 2 1 1 3 3 3 0 Flavin-binding monooxygenase-like MADF_DNA_bdg PF10545.9 CRK18446.1 - 6.5 7.1 5.3 0.95 9.8 0.9 1.9 2 0 0 2 2 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Relaxase PF03432.14 CRK18446.1 - 8.1 6.0 7.4 2.1 7.9 3.9 1.7 2 0 0 2 2 2 0 Relaxase/Mobilisation nuclease domain VTC PF09359.10 CRK18447.1 - 2.5e-58 197.7 0.2 3.7e-58 197.1 0.2 1.2 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.15 CRK18447.1 - 1.6e-12 47.6 3.3 1.6e-12 47.6 3.3 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.19 CRK18447.1 - 0.01 15.8 15.1 0.042 13.8 15.1 2.0 1 1 0 1 1 1 0 SPX domain MgtE PF01769.16 CRK18447.1 - 0.083 13.3 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 Divalent cation transporter Zn_clus PF00172.18 CRK18448.1 - 3.4e-08 33.5 9.5 6.4e-08 32.6 9.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 CRK18448.1 - 3.1e-06 26.2 0.3 5e-06 25.6 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain CitX PF03802.14 CRK18448.1 - 0.094 12.5 0.5 0.42 10.4 0.3 2.0 2 0 0 2 2 2 0 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase Glyco_hydro_cc PF11790.8 CRK18449.1 - 1.3e-52 178.8 0.8 1.6e-52 178.5 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core zf-RING_2 PF13639.6 CRK18451.1 - 4.6e-12 46.1 3.4 1.2e-11 44.8 3.4 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 CRK18451.1 - 4.2e-09 36.0 0.8 8.7e-09 35.0 0.8 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 CRK18451.1 - 1.1e-06 28.4 3.3 1.1e-06 28.4 3.3 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CRK18451.1 - 2e-06 28.0 4.2 6.4e-06 26.4 4.2 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CRK18451.1 - 2.3e-05 24.1 2.8 2.3e-05 24.1 2.8 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CRK18451.1 - 3.8e-05 23.4 4.5 8.3e-05 22.4 4.5 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CRK18451.1 - 0.00071 19.5 2.3 0.0016 18.4 2.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CRK18451.1 - 0.0024 17.7 2.3 0.0059 16.5 2.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CRK18451.1 - 0.0039 17.2 0.8 0.0091 16.0 0.8 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 CRK18451.1 - 0.012 15.7 7.1 0.024 14.7 3.2 2.9 2 1 0 2 2 2 0 RING-type zinc-finger zf-RING_4 PF14570.6 CRK18451.1 - 0.047 13.5 2.8 0.099 12.5 2.8 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Rad50_zn_hook PF04423.14 CRK18451.1 - 0.13 12.1 1.9 0.25 11.2 0.4 2.0 2 0 0 2 2 2 0 Rad50 zinc hook motif Prok-RING_1 PF14446.6 CRK18451.1 - 0.17 11.9 5.0 1 9.3 1.9 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHD PF00628.29 CRK18451.1 - 0.72 9.8 3.0 1.8 8.5 3.0 1.7 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.8 CRK18451.1 - 0.8 9.9 3.2 9 6.6 3.2 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain Ubiquitin_2 PF14560.6 CRK18452.1 - 7.9e-22 77.5 0.0 1.2e-21 77.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain CAP_GLY PF01302.25 CRK18452.1 - 2.2e-21 75.6 1.4 3.2e-21 75.1 1.4 1.2 1 0 0 1 1 1 1 CAP-Gly domain ubiquitin PF00240.23 CRK18452.1 - 0.00062 19.5 0.0 0.0073 16.0 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin family Myb_DNA-binding PF00249.31 CRK18453.1 - 2.2e-13 50.2 2.2 1.8e-10 40.9 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CRK18453.1 - 0.00025 21.2 2.6 0.021 15.0 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain SelP_N PF04592.14 CRK18453.1 - 0.35 10.2 3.7 0.56 9.6 3.7 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Methyltransf_11 PF08241.12 CRK18454.1 - 9.1e-09 35.9 0.0 2.7e-08 34.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK18454.1 - 9.4e-08 32.7 0.1 2e-06 28.4 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CRK18454.1 - 1.9e-06 27.8 0.0 3.1e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK18454.1 - 3.2e-05 24.6 0.0 0.00013 22.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK18454.1 - 0.0026 17.6 0.0 0.048 13.5 0.1 2.1 2 0 0 2 2 2 1 Methyltransferase domain Nup96 PF12110.8 CRK18454.1 - 0.099 11.7 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Nuclear protein 96 OpuAC PF04069.12 CRK18455.1 - 0.12 12.0 0.0 19 4.7 0.0 2.7 3 0 0 3 3 3 0 Substrate binding domain of ABC-type glycine betaine transport system Nre_C PF04895.12 CRK18462.1 - 0.014 15.3 0.1 0.061 13.2 0.0 2.1 2 1 0 2 2 2 0 Archaeal Nre, C-terminal Nitr_red_assoc PF09655.10 CRK18462.1 - 2.2 8.9 7.6 14 6.3 3.0 2.7 2 1 1 3 3 3 0 Conserved nitrate reductase-associated protein (Nitr_red_assoc) DUF4217 PF13959.6 CRK18465.1 - 3.5e-16 59.2 0.1 7.3e-16 58.2 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) DNA_pol_B PF00136.21 CRK18466.1 - 0.0021 16.9 0.1 0.0025 16.6 0.1 1.0 1 0 0 1 1 1 1 DNA polymerase family B STE PF02200.16 CRK18470.1 - 5.1e-28 97.7 0.0 7.2e-28 97.2 0.0 1.2 1 0 0 1 1 1 1 STE like transcription factor DUF938 PF06080.12 CRK18470.1 - 0.001 18.9 0.0 0.0012 18.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Glutaredoxin PF00462.24 CRK18477.1 - 1e-17 64.0 0.0 1.5e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Sec1 PF00995.23 CRK18479.1 - 5.5e-38 131.6 0.1 5.9e-38 131.5 0.1 1.0 1 0 0 1 1 1 1 Sec1 family SART-1 PF03343.13 CRK18480.1 - 3.5e-40 138.2 8.4 4.6e-40 137.8 8.4 1.2 1 0 0 1 1 1 1 SART-1 family Cation_ATPase PF13246.6 CRK18481.1 - 3.1e-23 81.6 0.0 5.4e-23 80.9 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) PT-TG PF14449.6 CRK18481.1 - 0.026 14.4 0.0 0.053 13.4 0.0 1.4 1 0 0 1 1 1 0 Pre-toxin TG MFS_1 PF07690.16 CRK18494.1 - 6.2e-21 74.7 54.3 1.6e-12 47.0 27.2 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Hemerythrin PF01814.23 CRK18494.1 - 1.9e-08 35.0 2.9 3e-08 34.4 2.9 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Sec23_BS PF08033.12 CRK18494.1 - 0.13 13.0 0.2 0.54 11.0 0.0 2.1 3 0 0 3 3 3 0 Sec23/Sec24 beta-sandwich domain Ctr PF04145.15 CRK18497.1 - 8.7e-39 133.5 0.1 1.1e-38 133.1 0.1 1.1 1 0 0 1 1 1 1 Ctr copper transporter family YfhO PF09586.10 CRK18497.1 - 1.9 6.6 7.0 2.8 6.0 7.0 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO WD40 PF00400.32 CRK18499.1 - 2.4e-10 40.8 3.5 8.4e-06 26.4 0.3 5.0 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK18499.1 - 0.00049 20.3 0.1 0.37 11.1 0.1 3.6 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain zinc_ribbon_16 PF17034.5 CRK18499.1 - 0.19 11.9 1.0 0.53 10.5 1.0 1.6 1 0 0 1 1 1 0 Zinc-ribbon like family zinc_ribbon_4 PF13717.6 CRK18499.1 - 1.6 8.7 5.7 0.38 10.7 1.7 2.1 1 1 1 2 2 2 0 zinc-ribbon domain DUF4379 PF14311.6 CRK18499.1 - 3.3 8.1 8.5 16 6.0 1.1 3.0 2 0 0 2 2 2 0 Probable Zinc-ribbon domain PHD PF00628.29 CRK18499.1 - 6.4 6.7 8.0 19 5.2 0.4 3.3 2 1 1 3 3 3 0 PHD-finger VPS38 PF17649.1 CRK18500.1 - 1.7e-13 50.2 0.9 2.2e-08 33.4 0.3 3.5 4 0 0 4 4 4 3 Vacuolar protein sorting 38 Atg14 PF10186.9 CRK18500.1 - 1.6e-11 43.9 8.6 9.4e-11 41.3 8.6 1.9 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 AAA_13 PF13166.6 CRK18500.1 - 5.4 5.5 8.5 3 6.4 6.0 1.6 2 0 0 2 2 2 0 AAA domain TNFR_c6 PF00020.18 CRK18502.1 - 4.9 7.6 13.9 5.5 7.5 2.6 2.6 1 1 1 2 2 2 0 TNFR/NGFR cysteine-rich region Nup188 PF10487.9 CRK18507.1 - 1.2e-34 119.5 0.1 5.5e-34 117.3 0.1 1.8 1 1 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 Nup188_C PF18378.1 CRK18509.1 - 4.4e-155 516.1 0.1 5.7e-155 515.7 0.1 1.1 1 0 0 1 1 1 1 Nuclear pore protein NUP188 C-terminal domain zf-Tim10_DDP PF02953.15 CRK18510.1 - 9.6e-18 63.6 5.3 1.4e-17 63.1 5.3 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger c-SKI_SMAD_bind PF08782.10 CRK18510.1 - 0.042 14.1 0.7 0.062 13.5 0.7 1.3 1 0 0 1 1 1 0 c-SKI Smad4 binding domain DUF86 PF01934.17 CRK18510.1 - 0.08 12.8 0.1 0.086 12.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF86 ABC1 PF03109.16 CRK18512.1 - 7.1e-23 81.0 0.0 3.9e-13 49.6 0.0 2.3 2 0 0 2 2 2 2 ABC1 family APH PF01636.23 CRK18512.1 - 0.02 14.8 0.1 0.067 13.1 0.0 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 CRK18512.1 - 0.023 14.3 0.0 0.19 11.3 0.0 2.0 2 0 0 2 2 2 0 RIO1 family COesterase PF00135.28 CRK18514.1 - 1.7e-94 317.5 0.0 2.2e-94 317.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CRK18514.1 - 5.1e-06 26.5 0.1 5.2e-05 23.2 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CRK18514.1 - 0.089 12.3 0.1 0.15 11.5 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family PNP_UDP_1 PF01048.20 CRK18516.1 - 1.7e-39 135.5 0.3 2e-39 135.2 0.3 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily COesterase PF00135.28 CRK18517.1 - 3.5e-05 22.9 0.0 4e-05 22.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family DUF2347 PF09804.9 CRK18521.1 - 1e-104 350.2 0.0 1.2e-104 349.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) SPA PF08616.10 CRK18521.1 - 6e-05 23.0 0.0 0.00021 21.2 0.0 1.7 1 1 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 CRK18521.1 - 0.0018 17.0 0.0 0.04 12.6 0.0 2.2 2 1 0 2 2 2 1 Transport protein Avl9 CSTF1_dimer PF16699.5 CRK18521.1 - 0.025 14.3 0.2 18 5.1 0.0 3.4 3 0 0 3 3 3 0 Cleavage stimulation factor subunit 1, dimerisation domain GRP PF07172.11 CRK18523.1 - 0.024 15.3 24.8 0.11 13.2 24.8 2.0 1 1 0 1 1 1 0 Glycine rich protein family SGT1 PF07093.11 CRK18526.1 - 6.3 5.1 6.5 9 4.6 6.5 1.1 1 0 0 1 1 1 0 SGT1 protein CPSF_A PF03178.15 CRK18529.1 - 1.7e-75 254.3 0.0 4.3e-75 253.0 0.0 1.7 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.9 CRK18529.1 - 1.7e-17 63.2 0.0 5.3e-17 61.6 0.0 1.8 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term FAD_binding_4 PF01565.23 CRK18530.1 - 1.5e-25 89.5 4.2 3.1e-25 88.5 4.2 1.6 1 0 0 1 1 1 1 FAD binding domain adh_short PF00106.25 CRK18530.1 - 8.2e-21 74.3 0.0 1.3e-17 63.9 0.0 2.6 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 CRK18530.1 - 1.1e-10 41.4 0.0 3.1e-09 36.7 0.0 2.2 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK18530.1 - 9.5e-05 22.4 0.2 0.00026 21.0 0.2 1.6 1 0 0 1 1 1 1 KR domain BBE PF08031.12 CRK18530.1 - 0.00014 21.9 0.0 0.00031 20.8 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like GDP_Man_Dehyd PF16363.5 CRK18530.1 - 0.02 14.3 0.0 0.031 13.7 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Fungal_trans_2 PF11951.8 CRK18531.1 - 3.8e-07 29.3 2.4 5.4e-07 28.7 2.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain PNRC PF15365.6 CRK18531.1 - 0.12 12.2 0.3 0.37 10.7 0.3 1.9 1 0 0 1 1 1 0 Proline-rich nuclear receptor coactivator motif CFEM PF05730.11 CRK18532.1 - 8.4e-08 32.2 9.8 1.4e-07 31.5 9.8 1.4 1 0 0 1 1 1 1 CFEM domain Fringe PF02434.16 CRK18533.1 - 1.9e-09 37.4 0.0 3e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Fringe-like PAN_3 PF08277.12 CRK18533.1 - 0.017 14.9 0.0 0.036 13.9 0.0 1.5 1 0 0 1 1 1 0 PAN-like domain PAN_4 PF14295.6 CRK18533.1 - 0.022 14.7 1.4 0.07 13.1 0.7 2.1 2 0 0 2 2 2 0 PAN domain Galactosyl_T PF01762.21 CRK18533.1 - 0.036 13.9 0.0 0.64 9.8 0.0 2.1 1 1 0 1 1 1 0 Galactosyltransferase PAN_1 PF00024.26 CRK18533.1 - 0.038 14.0 0.4 0.078 12.9 0.4 1.4 1 0 0 1 1 1 0 PAN domain adh_short_C2 PF13561.6 CRK18534.1 - 0.0028 17.3 0.0 0.0028 17.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ank_5 PF13857.6 CRK18536.1 - 2.4e-05 24.5 0.2 0.001 19.3 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 CRK18536.1 - 0.00021 21.8 0.0 0.008 16.7 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 CRK18536.1 - 0.029 14.8 0.0 0.062 13.8 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeat Ank_2 PF12796.7 CRK18536.1 - 0.15 12.6 0.0 0.65 10.6 0.0 1.9 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Peptidase_M24 PF00557.24 CRK18540.1 - 8.3e-47 159.6 0.0 9.1e-47 159.4 0.0 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF3793 PF12672.7 CRK18540.1 - 0.21 11.6 0.0 0.28 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3793) Synaptobrevin PF00957.21 CRK18543.1 - 0.1 12.4 1.9 0.12 12.2 0.8 1.7 1 1 1 2 2 2 0 Synaptobrevin DUF4855 PF16147.5 CRK18543.1 - 0.11 11.6 0.1 0.12 11.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4855) DUF2935 PF11155.8 CRK18543.1 - 0.12 12.7 2.0 0.23 11.8 2.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) Chitin_synth_2 PF03142.15 CRK18546.1 - 5e-48 164.0 1.6 5.6e-48 163.8 1.6 1.0 1 0 0 1 1 1 1 Chitin synthase DUF3377 PF11857.8 CRK18546.1 - 0.72 9.8 2.1 1.2 9.1 2.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) ATP-synt_ab PF00006.25 CRK18551.1 - 6.2e-19 68.5 0.0 7.2e-19 68.3 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain RsgA_GTPase PF03193.16 CRK18551.1 - 0.0019 18.1 0.1 0.0023 17.9 0.1 1.1 1 0 0 1 1 1 1 RsgA GTPase ATPase PF06745.13 CRK18551.1 - 0.0053 16.1 0.2 0.006 15.9 0.2 1.1 1 0 0 1 1 1 1 KaiC NB-ARC PF00931.22 CRK18551.1 - 0.0073 15.5 0.1 0.008 15.4 0.1 1.1 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.12 CRK18551.1 - 0.013 15.5 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 CRK18551.1 - 0.015 15.7 0.0 0.019 15.3 0.0 1.2 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.6 CRK18551.1 - 0.045 14.1 0.2 0.071 13.5 0.2 1.3 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 CRK18551.1 - 0.046 12.6 0.1 0.051 12.5 0.1 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain TsaE PF02367.17 CRK18551.1 - 0.049 13.6 0.1 0.058 13.4 0.1 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Pox_A32 PF04665.12 CRK18551.1 - 0.066 12.7 0.1 0.088 12.3 0.1 1.1 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_30 PF13604.6 CRK18551.1 - 0.067 12.9 0.0 0.088 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CRK18551.1 - 0.074 12.6 0.1 0.1 12.1 0.1 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 CRK18551.1 - 0.076 12.9 0.0 0.094 12.6 0.0 1.1 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DUF463 PF04317.12 CRK18551.1 - 0.08 11.9 0.0 0.093 11.6 0.0 1.1 1 0 0 1 1 1 0 YcjX-like family, DUF463 AAA_16 PF13191.6 CRK18551.1 - 0.094 13.1 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Roc PF08477.13 CRK18551.1 - 0.15 12.2 0.1 0.24 11.7 0.1 1.4 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase NAGLU_N PF12971.7 CRK18551.1 - 0.18 11.6 0.0 0.52 10.1 0.0 1.7 2 0 0 2 2 2 0 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain KAP_NTPase PF07693.14 CRK18551.1 - 0.25 10.5 0.0 0.25 10.5 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain Importin_rep_6 PF18829.1 CRK18552.1 - 1.6e-14 53.9 0.2 2.2e-14 53.5 0.2 1.2 1 0 0 1 1 1 1 Importin repeat 6 MIF4G_like_2 PF09090.11 CRK18552.1 - 0.046 13.2 0.0 0.067 12.7 0.0 1.3 1 0 0 1 1 1 0 MIF4G like DUF45 PF01863.17 CRK18552.1 - 0.11 12.6 0.2 1.3 9.1 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function DUF45 TraF_2 PF13729.6 CRK18552.1 - 0.13 11.6 0.3 0.18 11.2 0.3 1.1 1 0 0 1 1 1 0 F plasmid transfer operon, TraF, protein Pkinase PF00069.25 CRK18554.1 - 7.9e-41 140.2 0.0 9.4e-41 139.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK18554.1 - 4.6e-21 75.3 0.0 5.5e-21 75.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CRK18554.1 - 0.00015 21.8 0.3 0.02 14.8 0.1 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CRK18554.1 - 0.00063 19.2 0.1 0.0042 16.5 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 CRK18554.1 - 0.0043 16.0 0.0 0.0059 15.6 0.0 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CRK18554.1 - 0.0056 16.1 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 CRK18554.1 - 0.055 12.5 0.0 0.088 11.8 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Alpha-amylase PF00128.24 CRK18556.1 - 5.1e-09 36.1 0.0 6.4e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain TPR_12 PF13424.6 CRK18556.1 - 0.021 15.1 0.4 0.065 13.5 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 CRK18556.1 - 0.057 13.5 0.5 0.37 10.9 0.1 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 CRK18556.1 - 0.11 13.2 0.3 1.1 10.1 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat AtuA PF07287.11 CRK18559.1 - 1.1e-137 458.5 0.1 1.4e-137 458.2 0.1 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA CFEM PF05730.11 CRK18559.1 - 0.01 15.9 10.8 0.023 14.8 10.8 1.5 1 0 0 1 1 1 0 CFEM domain Sugar_tr PF00083.24 CRK18560.1 - 3.2e-77 260.3 26.2 3.7e-77 260.1 26.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK18560.1 - 1.2e-24 86.9 32.6 2.7e-23 82.5 19.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1077 PF06417.12 CRK18562.1 - 3.1e-34 117.5 3.0 3.5e-34 117.3 3.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Adaptin_N PF01602.20 CRK18563.1 - 1.3e-37 129.6 1.2 2.7e-37 128.5 0.6 1.5 1 1 1 2 2 2 1 Adaptin N terminal region Cnd1 PF12717.7 CRK18563.1 - 1.5e-22 80.4 3.3 2.2e-22 79.8 0.8 2.1 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CRK18563.1 - 2.2e-09 36.8 1.7 4e-05 23.5 0.0 3.5 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 CRK18563.1 - 3.6e-09 36.9 3.0 5.4e-09 36.3 1.0 2.1 2 0 0 2 2 2 1 HEAT repeats HEAT_EZ PF13513.6 CRK18563.1 - 0.001 19.5 5.7 1.7 9.2 0.0 4.4 4 0 0 4 4 4 2 HEAT-like repeat CLASP_N PF12348.8 CRK18563.1 - 0.0096 15.5 0.0 0.018 14.6 0.0 1.6 1 1 0 1 1 1 1 CLASP N terminal RTP1_C1 PF10363.9 CRK18563.1 - 0.011 15.9 0.1 0.02 15.0 0.1 1.5 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF4042 PF13251.6 CRK18563.1 - 0.18 11.5 0.8 3.5 7.3 0.0 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4042) Chitin_synth_1 PF01644.17 CRK18565.1 - 7.3e-51 172.4 0.0 1.5e-50 171.4 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 CRK18565.1 - 3.8e-24 85.2 5.1 2.1e-20 72.8 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase ABC_tran PF00005.27 CRK18565.1 - 1.6e-10 41.7 0.0 7.6e-10 39.4 0.0 2.0 1 1 0 1 1 1 1 ABC transporter Glyco_trans_2_3 PF13632.6 CRK18565.1 - 7.7e-09 35.7 0.2 7.7e-09 35.7 0.2 3.1 2 1 1 3 3 3 1 Glycosyl transferase family group 2 AAA_21 PF13304.6 CRK18565.1 - 0.0013 18.6 0.0 0.0097 15.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system ECH_1 PF00378.20 CRK18567.1 - 4.1e-37 127.8 0.3 7.1e-36 123.8 0.2 2.1 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CRK18567.1 - 8.5e-18 64.9 0.1 2.9e-17 63.2 0.1 1.8 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase MFS_1 PF07690.16 CRK18569.1 - 3.2e-32 111.8 72.7 5.1e-14 52.0 16.5 3.3 1 1 2 3 3 3 3 Major Facilitator Superfamily Cation_ATPase_C PF00689.21 CRK18569.1 - 0.00095 18.9 7.0 0.14 11.9 0.6 3.3 3 1 0 3 3 3 2 Cation transporting ATPase, C-terminus UPF0086 PF01868.16 CRK18571.1 - 6.9e-30 102.8 0.0 1.1e-29 102.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Acyltransferase PF01553.21 CRK18572.1 - 8.7e-17 61.0 0.0 1.9e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase MFS_1 PF07690.16 CRK18574.1 - 8.4e-05 21.6 9.9 0.00011 21.2 9.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TPR_11 PF13414.6 CRK18574.1 - 0.00013 21.5 0.4 0.00028 20.5 0.4 1.5 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.17 CRK18574.1 - 0.0013 18.7 0.1 0.048 13.8 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 CRK18574.1 - 0.0013 18.4 0.0 0.27 11.1 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 CRK18574.1 - 0.0095 16.2 0.5 0.031 14.6 0.3 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat Asp-Al_Ex PF06826.12 CRK18574.1 - 0.03 14.2 3.4 0.047 13.5 3.4 1.2 1 0 0 1 1 1 0 Predicted Permease Membrane Region DUF4366 PF14283.6 CRK18574.1 - 0.035 14.2 0.3 0.035 14.2 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) SpoIIIAH PF12685.7 CRK18574.1 - 0.23 11.3 8.2 1.1 9.0 5.3 2.1 2 0 0 2 2 2 0 SpoIIIAH-like protein Acyltransferase PF01553.21 CRK18579.1 - 8.8e-17 61.0 0.0 1.9e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase Fungal_trans_2 PF11951.8 CRK18581.1 - 3.2e-20 72.3 1.0 4.4e-09 35.6 0.1 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK18581.1 - 9.5e-10 38.5 28.7 3.4e-06 27.1 10.3 3.3 4 0 0 4 4 4 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Phosphodiest PF01663.22 CRK18581.1 - 0.12 11.9 0.9 14 5.2 0.1 2.3 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase Hol_Tox PF16935.5 CRK18581.1 - 0.18 11.9 0.0 34 4.6 0.0 2.4 2 0 0 2 2 2 0 Putative Holin-like Toxin (Hol-Tox) HAD_2 PF13419.6 CRK18583.1 - 2.5e-21 76.5 0.0 9.3e-15 55.2 0.0 2.6 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CRK18583.1 - 3.6e-11 43.8 0.0 2.2e-06 28.1 0.0 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CRK18583.1 - 0.0012 18.8 0.0 0.0022 18.0 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 CRK18583.1 - 0.019 15.0 0.0 29 4.9 0.0 3.1 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase TPR_2 PF07719.17 CRK18584.1 - 1.3e-05 24.9 1.1 0.055 13.6 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 CRK18584.1 - 5.1e-05 22.9 0.9 0.29 11.0 0.0 3.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 CRK18584.1 - 9.7e-05 22.6 0.9 0.00027 21.2 0.9 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 CRK18584.1 - 0.00011 21.8 0.3 0.00033 20.3 0.3 1.8 1 0 0 1 1 1 1 TPR repeat TPR_7 PF13176.6 CRK18584.1 - 0.0022 17.9 0.9 0.28 11.3 0.1 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 CRK18584.1 - 0.015 15.8 0.3 0.063 13.8 0.3 2.2 1 1 0 1 1 1 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CRK18584.1 - 0.13 12.5 2.0 0.73 10.1 2.0 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 SpoIIIAH PF12685.7 CRK18584.1 - 9.7 6.0 12.5 1 9.2 4.9 2.2 2 0 0 2 2 2 0 SpoIIIAH-like protein Trimer_CC PF08954.11 CRK18588.1 - 0.003 17.1 0.8 0.0088 15.6 0.8 1.8 1 0 0 1 1 1 1 Trimerisation motif GAS PF13851.6 CRK18588.1 - 0.025 13.9 0.2 0.025 13.9 0.2 1.7 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding GCN5L1 PF06320.13 CRK18588.1 - 0.027 14.6 0.3 0.027 14.6 0.3 1.9 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) DUF3958 PF13125.6 CRK18588.1 - 0.029 14.6 1.1 0.063 13.5 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3958) YabA PF06156.13 CRK18588.1 - 0.036 14.7 0.4 0.036 14.7 0.4 1.7 2 0 0 2 2 2 0 Initiation control protein YabA ATG16 PF08614.11 CRK18588.1 - 0.26 11.5 15.7 0.88 9.8 15.7 1.7 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF4201 PF13870.6 CRK18588.1 - 0.57 9.9 6.0 0.77 9.5 1.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) FAM184 PF15665.5 CRK18588.1 - 0.59 9.9 7.0 1.7 8.4 7.0 1.7 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B Uso1_p115_C PF04871.13 CRK18588.1 - 0.65 10.4 7.8 0.15 12.4 2.2 2.3 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Cnn_1N PF07989.11 CRK18588.1 - 1.6 9.0 8.5 0.31 11.2 1.6 3.0 3 1 0 3 3 3 0 Centrosomin N-terminal motif 1 Taxilin PF09728.9 CRK18588.1 - 3.7 6.6 8.6 0.55 9.4 1.4 2.0 1 1 1 2 2 2 0 Myosin-like coiled-coil protein Chitin_bind_1 PF00187.19 CRK18590.1 - 1.1e-53 179.4 148.5 1e-09 38.7 17.9 7.7 6 3 2 8 8 8 6 Chitin recognition protein ACC_epsilon PF13822.6 CRK18590.1 - 0.63 10.8 2.0 1.1 10.0 2.0 1.3 1 0 0 1 1 1 0 Acyl-CoA carboxylase epsilon subunit p450 PF00067.22 CRK18591.1 - 1.4e-33 116.4 0.0 1.8e-33 116.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 CRK18593.1 - 3.3e-30 105.2 26.1 1.3e-29 103.2 23.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1003 PF06210.11 CRK18593.1 - 2.9 8.0 5.1 15 5.8 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1003) GFO_IDH_MocA PF01408.22 CRK18597.1 - 2.5e-15 57.4 0.1 6.1e-07 30.3 0.0 2.3 1 1 1 2 2 2 2 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 CRK18597.1 - 4.5e-11 42.8 0.0 7e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain DapB_N PF01113.20 CRK18597.1 - 0.00039 20.5 0.1 0.0006 19.9 0.1 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Gp_dh_N PF00044.24 CRK18597.1 - 0.0074 16.6 0.0 0.016 15.5 0.0 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain MFS_1 PF07690.16 CRK18599.1 - 2.1e-20 73.0 26.5 2.1e-20 73.0 26.5 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK18599.1 - 0.00015 20.8 3.3 0.00015 20.8 3.3 3.8 3 1 0 3 3 3 1 Sugar (and other) transporter Peptidase_M56 PF05569.11 CRK18599.1 - 0.00029 20.1 1.9 0.039 13.1 0.1 2.4 2 0 0 2 2 2 2 BlaR1 peptidase M56 DUF5336 PF17270.2 CRK18599.1 - 0.84 9.2 0.0 0.84 9.2 0.0 3.5 3 0 0 3 3 3 0 Family of unknown function (DUF5336) Phage_holin_7_1 PF16081.5 CRK18599.1 - 2.1 8.6 6.0 1.7 8.8 0.2 2.7 2 0 0 2 2 2 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family BCS1_N PF08740.11 CRK18602.1 - 3.1e-41 141.4 0.0 4.8e-41 140.8 0.0 1.3 1 0 0 1 1 1 1 BCS1 N terminal DUF2263 PF10021.9 CRK18602.1 - 3e-22 79.6 0.0 6.6e-22 78.5 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) AAA PF00004.29 CRK18602.1 - 4.2e-17 62.8 0.0 6.9e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Hydrophobin_2 PF06766.11 CRK18602.1 - 6.7e-12 45.2 1.6 1.3e-11 44.3 1.6 1.4 1 0 0 1 1 1 1 Fungal hydrophobin AAA_7 PF12775.7 CRK18602.1 - 0.00032 20.3 0.0 0.00065 19.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_25 PF13481.6 CRK18602.1 - 0.00032 20.3 0.0 0.02 14.4 0.0 2.6 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 CRK18602.1 - 0.0041 16.9 0.0 0.0091 15.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CRK18602.1 - 0.0058 16.6 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 CRK18602.1 - 0.0099 15.6 0.0 0.027 14.2 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF815 PF05673.13 CRK18602.1 - 0.014 14.5 0.0 0.032 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_16 PF13191.6 CRK18602.1 - 0.015 15.7 0.1 0.059 13.8 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 CRK18602.1 - 0.022 15.3 0.0 0.053 14.0 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Mg_chelatase PF01078.21 CRK18602.1 - 0.023 14.1 0.1 3.6 6.9 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 CRK18602.1 - 0.024 15.2 0.0 0.052 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CRK18602.1 - 0.031 14.5 0.0 0.064 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 CRK18602.1 - 0.048 13.7 0.0 0.15 12.2 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase PPV_E1_C PF00519.17 CRK18602.1 - 0.051 12.4 0.0 0.074 11.9 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase AAA_33 PF13671.6 CRK18602.1 - 0.069 13.3 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain GTSE1_N PF15259.6 CRK18602.1 - 0.078 13.2 0.1 0.2 11.9 0.1 1.6 1 0 0 1 1 1 0 G-2 and S-phase expressed 1 RNA_helicase PF00910.22 CRK18602.1 - 0.15 12.5 0.0 0.38 11.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ATP_bind_1 PF03029.17 CRK18602.1 - 0.21 11.3 0.0 0.38 10.5 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 CRK18602.1 - 0.22 11.4 0.0 0.39 10.6 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase DUF3169 PF11368.8 CRK18604.1 - 0.037 13.6 1.2 0.085 12.4 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) DUF2427 PF10348.9 CRK18604.1 - 0.061 13.1 9.5 0.22 11.3 1.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) DEC-1_N PF04625.13 CRK18604.1 - 0.83 8.6 6.9 1.4 7.8 6.9 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Glyco_hydro_61 PF03443.14 CRK18606.1 - 1.2e-34 120.0 0.0 2.1e-34 119.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Methyltransf_23 PF13489.6 CRK18606.1 - 1e-21 77.5 0.0 1.7e-21 76.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK18606.1 - 4.7e-11 43.2 0.0 1.2e-10 41.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK18606.1 - 1.3e-10 41.3 0.0 1e-09 38.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CRK18606.1 - 2e-09 38.0 0.0 5.1e-09 36.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK18606.1 - 4.2e-07 30.6 0.0 3.4e-06 27.7 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.19 CRK18606.1 - 0.00011 22.4 0.0 0.00021 21.5 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 CRK18606.1 - 0.052 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_2 PF00891.18 CRK18606.1 - 0.11 11.7 0.1 0.5 9.6 0.0 1.9 2 0 0 2 2 2 0 O-methyltransferase domain Acetyltransf_10 PF13673.7 CRK18608.1 - 0.0051 16.7 0.0 0.0082 16.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CRK18608.1 - 0.0088 16.3 0.1 0.012 15.8 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 CRK18608.1 - 0.14 12.3 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF4139 PF13598.6 CRK18610.1 - 3e-12 46.7 0.0 3.7e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4139) DUF2606 PF10794.9 CRK18610.1 - 0.18 11.6 0.0 2 8.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2606) Myosin_head PF00063.21 CRK18622.1 - 1.6e-127 426.6 0.5 1e-124 417.3 0.2 2.0 1 1 1 2 2 2 2 Myosin head (motor domain) Flu_NS1 PF00600.19 CRK18622.1 - 0.038 13.6 0.0 0.21 11.1 0.0 1.9 2 0 0 2 2 2 0 Influenza non-structural protein (NS1) HSF_DNA-bind PF00447.17 CRK18622.1 - 0.041 14.5 0.2 0.13 12.9 0.2 1.8 1 0 0 1 1 1 0 HSF-type DNA-binding MCM_OB PF17207.3 CRK18624.1 - 5e-23 81.3 0.1 6.4e-23 81.0 0.1 1.1 1 0 0 1 1 1 1 MCM OB domain Zn-ribbon_8 PF09723.10 CRK18624.1 - 0.091 12.9 0.4 0.22 11.7 0.4 1.7 1 0 0 1 1 1 0 Zinc ribbon domain ISN1 PF06437.11 CRK18626.1 - 4.7e-53 180.6 0.0 8.6e-53 179.7 0.0 1.4 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase Cse1 PF08506.10 CRK18626.1 - 3.5e-07 29.4 0.0 1.1e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 Cse1 Cnd1 PF12717.7 CRK18626.1 - 0.032 14.3 0.2 0.1 12.7 0.2 1.8 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 Importin_rep_6 PF18829.1 CRK18626.1 - 0.052 13.7 0.1 0.3 11.2 0.1 2.4 1 0 0 1 1 1 0 Importin repeat 6 Vac14_Fab1_bd PF12755.7 CRK18626.1 - 0.06 14.0 3.7 0.38 11.4 0.1 3.7 4 1 0 4 4 4 0 Vacuolar 14 Fab1-binding region TBP PF00352.21 CRK18627.1 - 8.5e-40 134.6 0.1 2.9e-22 78.4 0.0 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 CRK18627.1 - 0.019 15.0 0.0 0.66 10.1 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3378) Got1 PF04178.12 CRK18630.1 - 8.8e-16 58.3 10.4 2e-14 54.0 3.1 2.0 1 1 1 2 2 2 2 Got1/Sft2-like family PMP22_Claudin PF00822.20 CRK18630.1 - 0.21 11.5 2.3 0.39 10.6 2.3 1.5 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family TEA PF01285.18 CRK18635.1 - 2.4e-17 62.8 0.0 3.6e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 TEA/ATTS domain AP3D1 PF06375.11 CRK18635.1 - 0.094 12.9 0.1 0.11 12.7 0.1 1.0 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 WD40 PF00400.32 CRK18637.1 - 2.5e-24 85.1 14.2 3.4e-09 37.2 0.2 4.1 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.8 CRK18637.1 - 0.00039 19.2 4.3 0.023 13.4 0.2 2.8 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Pyrophosphatase PF00719.19 CRK18639.1 - 2.1e-36 125.2 0.2 2.3e-36 125.0 0.2 1.0 1 0 0 1 1 1 1 Inorganic pyrophosphatase RRM_1 PF00076.22 CRK18643.1 - 2.3e-07 30.6 0.0 3.3e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.25 CRK18647.1 - 1.5e-08 34.3 0.0 3e-08 33.3 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK18647.1 - 0.055 12.7 0.0 0.069 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase FAM216B PF15107.6 CRK18647.1 - 0.15 11.9 0.1 0.45 10.4 0.0 1.7 2 0 0 2 2 2 0 FAM216B protein family Fasciclin PF02469.22 CRK18648.1 - 1.2e-30 106.4 0.0 1.2e-18 67.6 0.0 2.4 2 0 0 2 2 2 2 Fasciclin domain FAD_binding_4 PF01565.23 CRK18648.1 - 1.3e-20 73.5 0.3 4.4e-20 71.8 0.3 2.0 1 0 0 1 1 1 1 FAD binding domain Peptidase_S41 PF03572.18 CRK18648.1 - 3.7e-07 29.9 0.0 7.5e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase family S41 TraW_N PF12477.8 CRK18648.1 - 0.059 13.3 1.1 0.29 11.1 1.1 2.3 1 0 0 1 1 1 0 Sex factor F TraW protein N terminal DUF4291 PF14124.6 CRK18651.1 - 1.2e-64 217.5 0.1 2.3e-64 216.6 0.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4291) Big_4 PF07532.11 CRK18651.1 - 0.043 13.5 0.0 1.7 8.5 0.0 2.3 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 4) NAD_binding_2 PF03446.15 CRK18653.1 - 1.6e-23 83.7 0.1 2.5e-23 83.0 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 CRK18653.1 - 1.4e-09 38.2 0.1 2.8e-09 37.3 0.1 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.20 CRK18653.1 - 0.003 17.6 0.0 0.0058 16.7 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DUF3818 PF12825.7 CRK18654.1 - 6e-49 166.9 0.0 5.2e-32 111.2 0.1 2.1 1 1 1 2 2 2 2 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 CRK18654.1 - 2.6e-42 143.9 0.1 4.5e-42 143.1 0.1 1.4 1 0 0 1 1 1 1 PX-associated RAP1 PF07218.11 CRK18654.1 - 4.9 5.3 10.0 8.3 4.5 10.0 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) GFA PF04828.14 CRK18656.1 - 1.2e-18 67.3 0.4 2.1e-18 66.5 0.4 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DUF4960 PF16324.5 CRK18656.1 - 0.14 11.7 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4960) Aldo_ket_red PF00248.21 CRK18657.1 - 1e-55 189.1 0.0 1.2e-55 188.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ADH_N PF08240.12 CRK18658.1 - 2.5e-25 88.5 3.8 4.5e-25 87.7 3.8 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CRK18658.1 - 2.8e-19 69.4 0.0 4.6e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CRK18658.1 - 3e-08 34.8 0.0 5.7e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 CRK18658.1 - 0.00044 19.6 0.0 0.00073 18.9 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 CRK18658.1 - 0.0028 17.1 0.3 0.0047 16.3 0.3 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Cyt-b5 PF00173.28 CRK18659.1 - 7.2e-13 48.5 0.0 9.4e-13 48.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Baculo_p74_N PF08404.10 CRK18660.1 - 0.21 10.6 0.0 0.24 10.5 0.0 1.1 1 0 0 1 1 1 0 Baculoviridae P74 N-terminal Scytalone_dh PF02982.14 CRK18661.1 - 4.3e-89 296.4 0.4 6.4e-89 295.8 0.4 1.3 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.6 CRK18661.1 - 0.00053 20.1 0.1 0.0011 19.1 0.1 1.5 1 0 0 1 1 1 1 SnoaL-like domain Trep_Strep PF09605.10 CRK18661.1 - 0.041 13.9 0.5 0.041 13.9 0.5 1.7 2 0 0 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) p450 PF00067.22 CRK18662.1 - 3.3e-62 210.7 0.0 1.3e-61 208.8 0.0 1.9 1 1 1 2 2 2 1 Cytochrome P450 AMP-binding PF00501.28 CRK18663.1 - 1.9e-80 270.5 0.0 3.4e-80 269.7 0.0 1.3 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.6 CRK18663.1 - 2.4e-10 41.2 0.3 5.8e-10 40.0 0.3 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Fungal_trans PF04082.18 CRK18664.1 - 2.3e-05 23.6 0.2 3.5e-05 23.0 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3328 PF11807.8 CRK18665.1 - 6e-52 176.6 0.3 7.6e-52 176.3 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3614 PF12267.8 CRK18667.1 - 0.035 14.6 0.2 0.043 14.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3614) Glyco_hydro_10 PF00331.20 CRK18668.1 - 4.3e-83 279.1 0.1 5.9e-83 278.6 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.18 CRK18668.1 - 3.8e-13 49.1 13.4 8.5e-13 48.0 13.4 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Mucin PF01456.17 CRK18668.1 - 0.00084 19.3 16.0 0.00084 19.3 16.0 2.6 2 0 0 2 2 2 1 Mucin-like glycoprotein Toxin_7 PF05980.12 CRK18668.1 - 0.51 10.6 2.8 0.98 9.7 2.8 1.4 1 0 0 1 1 1 0 Toxin 7 HLH PF00010.26 CRK18668.1 - 1.9 8.5 5.5 1.8 8.6 0.1 2.5 2 0 0 2 2 2 0 Helix-loop-helix DNA-binding domain DUF4666 PF15697.5 CRK18668.1 - 7.4 7.3 9.2 6.2 7.5 6.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4666) Myc_target_1 PF15179.6 CRK18671.1 - 0.00076 19.4 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 Myc target protein 1 LapA_dom PF06305.11 CRK18671.1 - 0.073 12.9 0.9 0.11 12.4 0.9 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Saf_2TM PF18303.1 CRK18671.1 - 0.12 12.0 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain Nitrate_red_gam PF02665.14 CRK18671.1 - 0.17 11.4 0.1 0.23 11.0 0.1 1.1 1 0 0 1 1 1 0 Nitrate reductase gamma subunit DUF4448 PF14610.6 CRK18671.1 - 0.22 11.3 0.0 0.26 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) FixS PF03597.15 CRK18671.1 - 1.8 8.4 5.1 2.6 7.8 5.1 1.2 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type SPX PF03105.19 CRK18672.1 - 7 6.5 12.1 7.6 6.3 12.1 1.3 1 0 0 1 1 1 0 SPX domain Annexin PF00191.20 CRK18673.1 - 5.5e-65 215.3 2.8 3e-18 65.6 0.1 4.3 4 1 0 4 4 4 4 Annexin MiaE PF06175.11 CRK18673.1 - 0.013 15.1 0.2 0.02 14.5 0.2 1.2 1 0 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) DUF3574 PF12098.8 CRK18673.1 - 0.017 14.9 0.1 6.2 6.7 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF3574) zf-C2H2_4 PF13894.6 CRK18674.1 - 0.011 16.5 1.6 1.1 10.3 0.8 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-CHY PF05495.12 CRK18674.1 - 0.15 12.5 0.7 0.3 11.6 0.7 1.4 1 0 0 1 1 1 0 CHY zinc finger zf-C2H2_11 PF16622.5 CRK18674.1 - 0.18 11.6 2.0 5.4 6.9 0.1 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-met PF12874.7 CRK18674.1 - 0.22 12.0 1.6 2.4 8.7 0.7 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CRK18674.1 - 0.31 11.4 1.5 2.1 8.7 0.9 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 CRK18674.1 - 0.46 11.0 2.4 3.2 8.4 0.5 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type Zn-ribbon_8 PF09723.10 CRK18674.1 - 0.87 9.8 4.4 8.8 6.5 4.4 2.3 1 1 1 2 2 2 0 Zinc ribbon domain SKG6 PF08693.10 CRK18675.1 - 3.6e-09 35.9 0.1 6e-09 35.2 0.1 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Podoplanin PF05808.11 CRK18675.1 - 0.0024 18.0 0.5 0.0037 17.4 0.5 1.3 1 0 0 1 1 1 1 Podoplanin Mid2 PF04478.12 CRK18675.1 - 0.0025 17.7 0.0 0.0043 16.9 0.0 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor DUF347 PF03988.12 CRK18675.1 - 0.061 13.5 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) MHYT PF03707.16 CRK18675.1 - 0.063 13.5 0.1 0.16 12.2 0.1 1.6 1 0 0 1 1 1 0 Bacterial signalling protein N terminal repeat Glycophorin_A PF01102.18 CRK18675.1 - 0.067 13.4 0.1 0.11 12.7 0.1 1.3 1 0 0 1 1 1 0 Glycophorin A NICE-1 PF15845.5 CRK18676.1 - 0.13 13.0 0.2 0.13 13.0 0.2 2.0 2 0 0 2 2 2 0 Cysteine-rich C-terminal 1 family Transglut_prok PF09017.10 CRK18678.1 - 7.2 5.8 9.1 8.1 5.7 9.1 1.0 1 0 0 1 1 1 0 Microbial transglutaminase GLEYA PF10528.9 CRK18680.1 - 1.5e-16 60.6 0.4 3e-16 59.6 0.4 1.5 1 0 0 1 1 1 1 GLEYA domain Glyco_hydro_43 PF04616.14 CRK18681.1 - 2e-15 56.9 1.0 3.6e-15 56.1 1.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Crystall_2 PF09076.10 CRK18681.1 - 0.13 12.2 1.4 0.32 10.9 0.1 2.4 2 0 0 2 2 2 0 Beta/Gamma crystallin YjbT PF17089.5 CRK18681.1 - 0.16 12.0 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family Big_3 PF07523.12 CRK18681.1 - 0.29 11.5 2.7 2.4 8.5 0.1 3.3 2 1 1 3 3 3 0 Bacterial Ig-like domain (group 3) ThrE PF06738.12 CRK18682.1 - 4.4e-71 239.1 19.3 1.9e-70 237.0 3.8 3.8 3 1 0 3 3 3 2 Putative threonine/serine exporter Sugar_tr PF00083.24 CRK18682.1 - 1.3e-05 24.3 5.8 1.3e-05 24.3 5.8 2.8 3 0 0 3 3 3 1 Sugar (and other) transporter ThrE_2 PF12821.7 CRK18682.1 - 4e-05 23.8 0.3 4e-05 23.8 0.3 5.1 6 0 0 6 6 6 1 Threonine/Serine exporter, ThrE MFS_1 PF07690.16 CRK18682.1 - 0.00022 20.3 13.0 0.00022 20.3 13.0 3.4 3 1 0 4 4 4 1 Major Facilitator Superfamily LapA_dom PF06305.11 CRK18682.1 - 0.71 9.7 3.9 16 5.4 0.1 3.1 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Hamartin PF04388.12 CRK18682.1 - 8.2 4.9 11.5 0.016 13.9 0.4 1.8 2 0 0 2 2 2 0 Hamartin protein p450 PF00067.22 CRK18683.1 - 8.4e-21 74.2 0.0 1.2e-19 70.5 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 PYC_OADA PF02436.18 CRK18693.1 - 1.4e-36 126.1 0.0 3e-36 125.0 0.0 1.5 2 0 0 2 2 2 1 Conserved carboxylase domain GCV_T PF01571.21 CRK18710.1 - 4.3e-38 131.2 0.1 5.2e-38 130.9 0.1 1.0 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain SoxG PF04268.12 CRK18710.1 - 0.027 14.6 0.1 0.068 13.3 0.1 1.7 1 1 0 1 1 1 0 Sarcosine oxidase, gamma subunit family AOX PF01786.17 CRK18713.1 - 3e-51 174.0 0.0 3.3e-51 173.9 0.0 1.0 1 0 0 1 1 1 1 Alternative oxidase NolX PF05819.11 CRK18715.1 - 0.064 12.6 9.5 0.09 12.1 9.5 1.2 1 0 0 1 1 1 0 NolX protein Med15 PF09606.10 CRK18715.1 - 6.1 5.4 37.3 7.8 5.0 37.3 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal HMG_CoA_synt_C PF08540.10 CRK18719.1 - 2.3e-43 148.8 0.0 2.9e-43 148.5 0.0 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal BCS1_N PF08740.11 CRK18719.1 - 1.6e-06 28.2 0.0 2.1e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 BCS1 N terminal Tic110 PF16940.5 CRK18719.1 - 0.14 10.6 0.0 0.18 10.2 0.0 1.1 1 0 0 1 1 1 0 Chloroplast envelope transporter SH2_2 PF14633.6 CRK18721.1 - 8.8e-26 90.6 0.0 1.2e-25 90.2 0.0 1.2 1 0 0 1 1 1 1 SH2 domain S1 PF00575.23 CRK18721.1 - 6.4e-05 23.2 0.9 9.6e-05 22.6 0.9 1.3 1 0 0 1 1 1 1 S1 RNA binding domain SH2 PF00017.24 CRK18721.1 - 0.015 15.3 0.0 0.026 14.6 0.0 1.4 1 0 0 1 1 1 0 SH2 domain THF_DHG_CYH_C PF02882.19 CRK18722.1 - 9.4e-22 77.0 0.1 1.2e-21 76.7 0.1 1.1 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 CRK18722.1 - 2.2e-15 56.9 0.3 3e-15 56.5 0.3 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain DUF3385 PF11865.8 CRK18724.1 - 0.034 14.0 0.1 0.09 12.7 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) PGA2 PF07543.12 CRK18726.1 - 4.5e-18 65.6 2.8 5.4e-18 65.3 2.8 1.0 1 0 0 1 1 1 1 Protein trafficking PGA2 Utp13 PF08625.11 CRK18727.1 - 7.7e-36 123.1 0.3 1.1e-35 122.5 0.2 1.4 1 1 0 1 1 1 1 Utp13 specific WD40 associated domain CENP-S PF15630.6 CRK18727.1 - 3e-25 88.4 0.0 7.6e-25 87.1 0.0 1.7 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 CRK18727.1 - 8.3e-05 22.7 0.8 0.0011 19.1 0.1 2.7 2 1 1 3 3 3 1 Centromere kinetochore component CENP-T histone fold UCH PF00443.29 CRK18729.1 - 2.7e-26 92.6 0.0 4e-26 92.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 CRK18729.1 - 1.2e-11 44.7 2.3 2.8e-11 43.6 0.3 2.1 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 CRK18729.1 - 0.0064 16.1 1.0 0.084 12.5 0.2 2.3 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUF1064 PF06356.11 CRK18729.1 - 0.029 14.7 0.1 0.066 13.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1064) IF4E PF01652.18 CRK18730.1 - 1.3e-46 158.3 0.1 1.7e-46 157.9 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E ANAPC3 PF12895.7 CRK18731.1 - 7.7e-28 96.5 11.6 2.5e-24 85.3 0.6 5.4 3 2 2 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 CRK18731.1 - 7.1e-23 78.8 14.1 0.011 15.8 0.0 10.1 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_1 PF00515.28 CRK18731.1 - 6.9e-21 73.1 4.3 0.023 14.5 0.0 9.1 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_19 PF14559.6 CRK18731.1 - 2.1e-19 69.8 9.7 0.0033 17.9 0.0 6.9 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.6 CRK18731.1 - 1.6e-18 66.8 13.4 2e-08 34.4 0.1 7.9 5 1 2 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 CRK18731.1 - 4.8e-14 51.9 14.7 0.052 14.4 0.0 8.9 4 2 5 9 9 9 3 Tetratricopeptide repeat TPR_8 PF13181.6 CRK18731.1 - 9.5e-14 50.4 1.5 7.6 7.0 0.0 8.7 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 CRK18731.1 - 4.5e-13 49.6 11.2 3.2e-06 27.7 0.1 7.1 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_10 PF13374.6 CRK18731.1 - 3e-11 42.8 6.4 0.00074 19.3 0.4 6.6 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.6 CRK18731.1 - 1.7e-07 30.8 11.5 0.18 11.9 0.1 8.1 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_6 PF13174.6 CRK18731.1 - 6.9e-07 29.5 6.6 13 6.7 0.1 7.3 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_9 PF13371.6 CRK18731.1 - 8.3e-05 22.7 3.3 0.0078 16.3 0.5 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 CRK18731.1 - 0.00076 19.1 7.7 1.1 9.0 0.0 5.7 6 2 2 8 8 8 2 TPR repeat TPR_17 PF13431.6 CRK18731.1 - 0.0017 18.6 3.0 8.2 7.1 0.0 6.5 9 0 0 9 9 7 1 Tetratricopeptide repeat TPR_15 PF13429.6 CRK18731.1 - 0.011 14.9 2.9 0.34 10.1 0.0 3.5 3 3 2 5 5 5 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 CRK18731.1 - 0.014 15.4 1.1 52 3.9 0.0 4.0 4 1 1 5 5 5 0 Putative TPR-like repeat TPR_4 PF07721.14 CRK18731.1 - 0.015 15.9 5.8 4 8.4 0.0 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_MalT PF17874.1 CRK18731.1 - 0.05 13.0 6.8 1.6 8.0 0.1 3.6 2 1 0 2 2 2 0 MalT-like TPR region SNAP PF14938.6 CRK18731.1 - 0.1 12.0 2.6 4.1 6.7 0.0 3.3 4 1 0 4 4 4 0 Soluble NSF attachment protein, SNAP Glyco_hydro_16 PF00722.21 CRK18732.1 - 4e-08 32.9 0.0 5.4e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 CRK18732.1 - 9.5e-06 24.3 1.4 0.014 13.8 1.3 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) AMP-binding PF00501.28 CRK18734.1 - 9.9e-42 143.0 0.0 1.7e-41 142.2 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 CRK18734.1 - 0.0015 18.4 0.1 0.0032 17.3 0.1 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Malic_M PF03949.15 CRK18735.1 - 4.1e-93 311.4 0.0 5.6e-93 310.9 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 CRK18735.1 - 1.6e-72 243.1 0.0 2.7e-72 242.4 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain PadR PF03551.14 CRK18735.1 - 0.019 14.9 0.2 0.14 12.2 0.0 2.2 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family SOG2 PF10428.9 CRK18735.1 - 1.6 7.9 10.2 2.2 7.4 10.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein NmrA PF05368.13 CRK18736.1 - 9.8e-17 61.3 0.0 3.5e-14 52.9 0.0 2.1 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 CRK18736.1 - 3.8e-10 40.0 0.1 9e-10 38.7 0.0 1.7 2 1 0 2 2 2 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 CRK18736.1 - 0.00025 21.5 0.0 0.00048 20.6 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 CRK18736.1 - 0.073 13.2 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DXP_reductoisom PF02670.16 CRK18736.1 - 0.078 13.7 0.1 0.32 11.7 0.0 2.1 2 1 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase SCP2_2 PF13530.6 CRK18736.1 - 0.32 11.4 2.4 1.2 9.5 0.1 2.7 3 0 0 3 3 3 0 Sterol carrier protein domain GAS2 PF02187.17 CRK18737.1 - 9.7e-07 28.8 0.0 2.8e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain FMO-like PF00743.19 CRK18739.1 - 7e-40 136.9 0.0 1.4e-23 83.1 0.0 3.0 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 CRK18739.1 - 4e-15 55.9 0.1 2.5e-09 36.8 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CRK18739.1 - 5.5e-14 52.1 0.0 2.8e-13 49.8 0.0 2.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CRK18739.1 - 5.9e-13 48.7 0.1 9.2e-11 41.5 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 CRK18739.1 - 9e-12 45.2 0.4 1.2e-08 35.1 0.1 4.1 3 2 1 4 4 4 1 FAD-NAD(P)-binding DAO PF01266.24 CRK18739.1 - 2.1e-10 40.8 0.7 0.00058 19.6 0.1 4.2 3 1 1 4 4 4 2 FAD dependent oxidoreductase Thi4 PF01946.17 CRK18739.1 - 3.6e-08 32.9 0.1 0.00013 21.3 0.0 2.4 3 0 0 3 3 3 2 Thi4 family NAD_binding_8 PF13450.6 CRK18739.1 - 9e-08 32.2 0.2 7.4e-07 29.3 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 CRK18739.1 - 1.9e-05 25.1 0.5 0.048 14.2 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CRK18739.1 - 3.3e-05 22.8 0.3 0.1 11.3 0.1 2.8 3 0 0 3 3 3 2 HI0933-like protein 2-Hacid_dh_C PF02826.19 CRK18739.1 - 0.00013 21.4 0.0 0.0041 16.5 0.0 2.2 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Amino_oxidase PF01593.24 CRK18739.1 - 0.00032 20.1 0.0 0.02 14.2 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 CRK18739.1 - 0.00047 19.5 0.1 0.069 12.4 0.0 2.4 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 CRK18739.1 - 0.0084 15.2 0.1 1.1 8.2 0.1 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 CRK18739.1 - 0.011 14.9 0.1 2.9 6.8 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein Shikimate_DH PF01488.20 CRK18739.1 - 0.017 15.2 0.0 2.8 8.0 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 CRK18739.1 - 0.038 14.4 0.0 6.6 7.2 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding IlvN PF07991.12 CRK18739.1 - 0.049 13.2 0.0 1.9 8.0 0.0 2.3 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain AlaDh_PNT_C PF01262.21 CRK18739.1 - 0.06 12.6 0.2 3.7 6.8 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 CRK18739.1 - 0.13 11.3 0.3 1.7 7.6 0.0 2.4 3 0 0 3 3 3 0 FAD binding domain POT1 PF02765.17 CRK18740.1 - 6.8e-11 42.2 0.0 3.8e-10 39.7 0.0 2.1 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 RGS-like PF09128.11 CRK18740.1 - 0.15 11.8 0.9 0.31 10.7 0.9 1.4 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain Fungal_trans PF04082.18 CRK18741.1 - 1.4e-33 116.1 0.4 1.4e-33 116.1 0.4 2.6 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK18741.1 - 5.9e-08 32.7 9.6 1.1e-07 31.8 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SelP_N PF04592.14 CRK18741.1 - 7.3 5.9 14.8 0.054 12.9 5.5 1.9 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Clr5 PF14420.6 CRK18742.1 - 2.8e-11 43.4 2.2 4.9e-11 42.7 2.2 1.4 1 0 0 1 1 1 1 Clr5 domain UPF0158 PF03682.13 CRK18742.1 - 0.067 13.2 0.7 0.081 12.9 0.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0158) Beta_helix PF13229.6 CRK18743.1 - 4.8e-14 52.5 8.2 7.6e-14 51.9 8.2 1.3 1 0 0 1 1 1 1 Right handed beta helix region NosD PF05048.13 CRK18743.1 - 8.2e-11 41.6 0.6 1.2e-10 41.0 0.6 1.2 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) DUF1565 PF07602.11 CRK18743.1 - 0.00019 20.8 6.5 0.0055 16.1 6.5 2.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1565) 2-Hacid_dh_C PF02826.19 CRK18744.1 - 2.6e-50 170.2 0.0 4.9e-50 169.4 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CRK18744.1 - 1.1e-15 57.5 0.0 1.6e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 CRK18744.1 - 0.00055 20.1 0.0 0.0012 19.1 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AA_permease_2 PF13520.6 CRK18745.1 - 1.4e-63 215.2 39.5 2.4e-63 214.4 39.5 1.3 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CRK18745.1 - 1.4e-28 99.8 26.6 1.4e-28 99.8 26.6 2.1 2 0 0 2 2 2 1 Amino acid permease DUF1754 PF08555.10 CRK18746.1 - 2.9e-14 53.6 18.1 5.5e-14 52.7 18.1 1.4 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) DUF5523 PF17661.1 CRK18746.1 - 0.15 11.7 12.5 0.19 11.4 12.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) CDC27 PF09507.10 CRK18746.1 - 0.17 11.2 19.1 0.2 11.0 19.1 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 RR_TM4-6 PF06459.12 CRK18746.1 - 2.1 8.1 12.4 2.6 7.8 12.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NOA36 PF06524.12 CRK18746.1 - 2.8 7.2 9.4 3.6 6.8 9.4 1.2 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 CRK18746.1 - 9.9 4.3 17.2 12 4.1 17.2 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF908 PF06012.12 CRK18747.1 - 4.8 6.5 8.1 6.2 6.1 1.6 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) ORC2 PF04084.14 CRK18749.1 - 9.1e-119 396.2 0.0 1.1e-118 396.0 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 NTP_transf_3 PF12804.7 CRK18749.1 - 0.049 14.0 0.9 0.12 12.7 0.3 1.8 1 1 1 2 2 2 0 MobA-like NTP transferase domain Phage_terminase PF10668.9 CRK18749.1 - 0.059 13.4 0.0 4.1 7.5 0.0 2.5 2 0 0 2 2 2 0 Phage terminase small subunit CutC PF03932.14 CRK18751.1 - 3.5e-14 52.7 0.0 4.1e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 CutC family TIP39 PF14980.6 CRK18752.1 - 0.07 13.0 0.1 2.9 7.8 0.0 2.6 2 0 0 2 2 2 0 TIP39 peptide Alk_phosphatase PF00245.20 CRK18753.1 - 1.4e-69 235.1 0.0 3.3e-69 233.9 0.0 1.5 1 1 0 1 1 1 1 Alkaline phosphatase Phosphodiest PF01663.22 CRK18753.1 - 5e-06 26.3 0.6 7.8e-06 25.7 0.6 1.4 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 CRK18753.1 - 5.6e-06 26.0 0.0 1e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.17 CRK18753.1 - 0.0024 16.6 0.9 0.0027 16.4 0.2 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF229) DUF1501 PF07394.12 CRK18753.1 - 0.046 12.8 0.2 0.071 12.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Kelch_4 PF13418.6 CRK18755.1 - 4.5e-20 71.4 2.7 0.0001 22.2 0.0 5.1 5 0 0 5 5 5 4 Galactose oxidase, central domain DUF924 PF06041.11 CRK18755.1 - 1.6e-18 67.4 0.1 2.8e-18 66.7 0.1 1.4 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) Kelch_5 PF13854.6 CRK18755.1 - 5.7e-17 61.3 1.0 0.0057 16.6 0.0 5.4 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.6 CRK18755.1 - 1.3e-13 50.8 1.2 0.00025 21.3 0.0 6.7 7 1 0 7 7 7 3 Galactose oxidase, central domain Kelch_6 PF13964.6 CRK18755.1 - 8.6e-10 38.6 1.7 0.075 13.3 0.0 5.0 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 CRK18755.1 - 3.1e-09 36.3 2.8 0.026 14.1 0.0 4.6 3 1 1 4 4 4 3 Kelch motif Kelch_2 PF07646.15 CRK18755.1 - 9.9e-05 22.2 3.7 1.5 8.9 0.0 5.4 6 0 0 6 6 6 1 Kelch motif DUF3157 PF11355.8 CRK18755.1 - 0.093 12.3 0.2 0.15 11.6 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3157) HOASN PF14515.6 CRK18755.1 - 0.12 12.8 0.2 0.34 11.3 0.2 1.7 1 0 0 1 1 1 0 Haem-oxygenase-associated N-terminal helices Sugar_tr PF00083.24 CRK18756.1 - 7.7e-81 272.2 10.6 8.9e-81 272.0 10.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK18756.1 - 8.2e-23 80.9 23.2 1.1e-22 80.5 21.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CRK18756.1 - 5.6e-07 28.4 0.2 8.8e-07 27.7 0.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 CRK18756.1 - 3e-05 22.8 2.9 0.0011 17.6 0.0 2.6 2 0 0 2 2 2 2 MFS/sugar transport protein DUF3104 PF11302.8 CRK18756.1 - 0.018 14.8 0.2 0.053 13.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3104) TraU PF06834.11 CRK18756.1 - 0.022 14.1 0.0 0.035 13.4 0.0 1.2 1 0 0 1 1 1 0 TraU protein OATP PF03137.20 CRK18756.1 - 0.036 12.4 4.9 0.032 12.5 1.1 2.7 3 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family MBOAT_2 PF13813.6 CRK18763.1 - 0.00015 22.0 0.4 0.0011 19.2 0.0 2.1 1 1 1 2 2 2 1 Membrane bound O-acyl transferase family PALP PF00291.25 CRK18767.1 - 2.1e-55 188.2 0.7 3.6e-55 187.5 0.7 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme MFS_1 PF07690.16 CRK18767.1 - 1.2e-30 106.6 46.1 1.5e-22 80.0 25.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Methyltransf_3 PF01596.17 CRK18767.1 - 2.6e-07 30.0 0.0 5.4e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 CRK18767.1 - 6e-07 30.5 0.0 4.4e-06 27.7 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain DUF4022 PF13214.6 CRK18769.1 - 2.7 8.3 6.2 0.93 9.8 1.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4022) Fungal_trans_2 PF11951.8 CRK18773.1 - 9e-48 163.0 5.2 1.1e-47 162.7 5.2 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain AAA_lid_6 PF17866.1 CRK18773.1 - 0.03 14.5 0.2 0.075 13.2 0.2 1.7 1 0 0 1 1 1 0 AAA lid domain NPP1 PF05630.11 CRK18775.1 - 1e-46 159.5 5.5 1.3e-46 159.2 5.5 1.1 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) DUF4190 PF13828.6 CRK18777.1 - 0.14 12.0 0.2 0.14 12.0 0.2 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4190) FAD_binding_4 PF01565.23 CRK18780.1 - 4.7e-25 87.9 1.8 7.7e-25 87.3 1.8 1.3 1 0 0 1 1 1 1 FAD binding domain Glyco_transf_54 PF04666.13 CRK18780.1 - 7.3e-12 44.7 0.0 1.1e-05 24.5 0.0 3.2 3 0 0 3 3 3 3 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region MFS_1 PF07690.16 CRK18783.1 - 9.4e-28 97.1 48.7 1.4e-26 93.2 38.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 CRK18783.1 - 0.0012 18.2 22.6 0.0028 17.0 22.6 1.5 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB TPPK_C PF12555.8 CRK18783.1 - 0.028 14.4 2.5 0.1 12.6 0.4 3.2 3 0 0 3 3 3 0 Thiamine pyrophosphokinase C terminal MFS_1 PF07690.16 CRK18786.1 - 2.4e-24 85.9 64.5 1.4e-21 76.9 57.3 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1269 PF06897.12 CRK18786.1 - 8.3 6.8 7.7 0.65 10.3 0.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1269) Lactamase_B_2 PF12706.7 CRK18788.1 - 5.7e-15 55.4 0.2 8.7e-15 54.8 0.2 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 CRK18788.1 - 3.9e-13 49.6 0.0 5.5e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 CRK18788.1 - 0.038 14.0 0.8 2.3 8.2 0.0 2.7 3 0 0 3 3 3 0 Metallo-beta-lactamase superfamily CoA_transf_3 PF02515.17 CRK18789.1 - 2.1e-63 214.7 0.0 2.6e-63 214.3 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III Amino_oxidase PF01593.24 CRK18791.1 - 1.5e-27 97.0 0.0 8.6e-27 94.5 0.0 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CRK18791.1 - 4.2e-10 39.7 0.0 2e-09 37.6 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 CRK18791.1 - 0.0013 18.1 0.0 0.0026 17.1 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CRK18791.1 - 0.0051 16.4 0.4 0.01 15.4 0.4 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CRK18791.1 - 0.0077 15.5 0.0 0.017 14.4 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CRK18791.1 - 0.016 14.4 0.1 0.025 13.8 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 CRK18791.1 - 0.045 12.5 0.4 0.068 11.9 0.4 1.2 1 0 0 1 1 1 0 HI0933-like protein ThiF PF00899.21 CRK18791.1 - 0.053 12.9 0.4 0.11 11.9 0.4 1.4 1 0 0 1 1 1 0 ThiF family FAD_binding_2 PF00890.24 CRK18791.1 - 0.14 11.2 0.2 0.24 10.4 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.16 CRK18791.1 - 0.18 11.4 0.6 0.31 10.7 0.6 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 CRK18791.1 - 0.24 12.0 0.1 0.48 11.0 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Amidoligase_2 PF12224.8 CRK18793.1 - 5.1e-16 59.1 0.1 2.9e-12 46.8 0.1 4.2 2 2 0 2 2 2 2 Putative amidoligase enzyme DUF5107 PF17128.4 CRK18795.1 - 0.0083 15.3 0.8 0.015 14.5 0.1 1.6 1 1 1 2 2 2 1 Domain of unknown function (DUF5107) GH43_C2 PF17851.1 CRK18795.1 - 0.16 11.7 0.1 0.27 11.0 0.1 1.4 1 0 0 1 1 1 0 Beta xylosidase C-terminal Concanavalin A-like domain CAP PF00188.26 CRK18797.1 - 4.4e-15 56.6 0.0 7e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family SNF5 PF04855.12 CRK18801.1 - 4.7e-93 311.3 0.0 6.8e-93 310.8 0.0 1.2 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.27 CRK18801.1 - 0.00016 21.2 0.7 0.00037 20.0 0.7 1.7 1 0 0 1 1 1 1 GATA zinc finger Fungal_trans PF04082.18 CRK18806.1 - 8.4e-17 61.1 0.0 2e-07 30.3 0.0 2.5 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK18806.1 - 2.4e-12 46.8 34.6 5.9e-06 26.3 13.3 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Vpu PF00558.19 CRK18806.1 - 0.013 15.3 0.9 4.5 7.1 0.1 2.6 2 0 0 2 2 2 0 Vpu protein TMF_TATA_bd PF12325.8 CRK18806.1 - 0.024 14.8 0.1 13 6.1 0.0 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding CCD48 PF15799.5 CRK18806.1 - 0.032 12.6 0.1 5.7 5.1 0.0 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 48 DUF485 PF04341.12 CRK18806.1 - 0.038 13.9 0.2 8.6 6.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF485 P19Arf_N PF07392.12 CRK18806.1 - 0.068 13.6 0.0 29 5.2 0.0 2.7 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor 2a p19Arf N-terminus DUF3397 PF11877.8 CRK18806.1 - 0.1 12.8 1.5 14 6.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3397) NicO PF03824.16 CRK18806.1 - 0.46 9.8 1.4 19 4.5 0.1 2.2 2 0 0 2 2 2 0 High-affinity nickel-transport protein Hexapep_loop PF18776.1 CRK18806.1 - 0.67 9.6 2.4 28 4.4 0.2 2.6 2 0 0 2 2 2 0 Hexapeptide repeat including loop Tcell_CD4_C PF12104.8 CRK18806.1 - 1.4 8.9 11.1 10 6.1 2.0 3.2 2 0 0 2 2 2 0 T cell CD4 receptor C terminal region Fungal_trans PF04082.18 CRK18808.1 - 1.1e-16 60.7 0.1 1.1e-16 60.7 0.1 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain TFIIA PF03153.13 CRK18808.1 - 0.2 11.6 38.9 0.34 10.9 38.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 CRK18808.1 - 0.57 8.4 33.9 0.78 7.9 33.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Exonuc_VII_L PF02601.15 CRK18808.1 - 5.4 6.5 15.0 0.78 9.2 11.0 1.5 2 0 0 2 2 2 0 Exonuclease VII, large subunit Presenilin PF01080.17 CRK18808.1 - 5.5 5.6 19.6 8.5 5.0 19.6 1.2 1 0 0 1 1 1 0 Presenilin HGTP_anticodon2 PF12745.7 CRK18808.1 - 5.9 6.3 15.0 11 5.5 15.0 1.3 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Sugar_tr PF00083.24 CRK18812.1 - 1e-66 225.7 31.5 5.4e-45 154.1 11.4 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CRK18812.1 - 2.7e-21 75.9 26.1 6.8e-21 74.6 26.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily PUCC PF03209.15 CRK18812.1 - 0.011 14.8 6.8 0.019 14.0 6.8 1.3 1 0 0 1 1 1 0 PUCC protein Annexin PF00191.20 CRK18814.1 - 4.1e-11 42.8 0.2 3.2e-07 30.3 0.0 2.3 2 1 0 2 2 2 2 Annexin Cation_ATPase PF13246.6 CRK18814.1 - 0.036 14.2 0.1 0.047 13.8 0.1 1.4 1 1 0 1 1 1 0 Cation transport ATPase (P-type) Fungal_trans PF04082.18 CRK18816.1 - 4e-17 62.1 0.1 4e-17 62.1 0.1 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK18816.1 - 1.2e-07 31.8 9.1 1.9e-07 31.1 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIA PF03153.13 CRK18816.1 - 0.2 11.6 39.0 0.34 10.8 39.0 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 CRK18816.1 - 0.82 7.9 33.9 1.2 7.4 33.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 HGTP_anticodon2 PF12745.7 CRK18816.1 - 2.8 7.4 15.2 4.7 6.6 15.2 1.3 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Presenilin PF01080.17 CRK18816.1 - 4.5 5.9 19.6 7 5.3 19.6 1.3 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 CRK18816.1 - 5.7 5.5 16.1 9.1 4.8 16.1 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Acetyltransf_1 PF00583.25 CRK18819.1 - 1.3e-13 51.2 0.0 2.1e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CRK18819.1 - 1.7e-09 37.7 0.0 3.1e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CRK18819.1 - 6e-09 36.2 0.0 8.7e-09 35.7 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CRK18819.1 - 0.0004 20.3 0.0 0.027 14.5 0.0 2.7 2 1 0 2 2 2 1 FR47-like protein Acetyltransf_9 PF13527.7 CRK18819.1 - 0.0057 16.7 0.0 0.016 15.3 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Annexin PF00191.20 CRK18820.1 - 5.2e-51 170.6 2.3 5.4e-15 55.2 0.1 4.2 4 0 0 4 4 4 4 Annexin DUF2255 PF10012.9 CRK18820.1 - 0.087 13.0 0.3 5.7 7.1 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2255) DUF2019 PF09450.10 CRK18820.1 - 0.94 9.5 4.9 0.35 10.8 1.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF2019) Ank_2 PF12796.7 CRK18824.1 - 1.2e-14 54.6 0.1 8.4e-08 32.7 0.5 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CRK18824.1 - 9.3e-12 44.1 0.9 0.00012 22.2 0.2 4.8 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 CRK18824.1 - 6.1e-11 42.4 1.4 5.6e-09 36.1 0.2 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 CRK18824.1 - 1.3e-10 41.6 1.5 1.5e-05 25.4 0.1 4.8 4 1 3 7 7 7 2 Ankyrin repeats (many copies) Ank PF00023.30 CRK18824.1 - 1.2e-05 25.5 6.6 0.003 17.9 1.4 3.4 4 0 0 4 4 4 2 Ankyrin repeat TetR_C_31 PF17940.1 CRK18824.1 - 0.041 14.1 2.9 0.11 12.7 0.3 2.8 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Cutinase PF01083.22 CRK18825.1 - 1.2e-41 142.7 0.0 1.6e-41 142.2 0.0 1.2 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 CRK18825.1 - 0.00042 19.9 0.0 0.00069 19.2 0.0 1.4 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_2 PF02230.16 CRK18825.1 - 0.0074 16.1 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 CRK18825.1 - 0.086 13.4 3.5 0.12 12.9 3.5 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family SbcD_C PF12320.8 CRK18826.1 - 1.8 8.9 4.7 20 5.6 0.1 2.9 2 1 0 2 2 2 0 Type 5 capsule protein repressor C-terminal domain VPS9 PF02204.18 CRK18827.1 - 1.4e-29 102.3 0.0 2.5e-29 101.6 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 CRK18827.1 - 2.1e-16 59.9 0.0 5.1e-16 58.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) CUE PF02845.16 CRK18827.1 - 1.7e-10 40.4 0.1 1.5e-09 37.4 0.0 2.3 2 0 0 2 2 2 1 CUE domain YppG PF14179.6 CRK18827.1 - 7 7.4 8.1 9.5 7.0 0.2 3.5 3 0 0 3 3 3 0 YppG-like protein Cutinase PF01083.22 CRK18828.1 - 1.7e-46 158.4 0.4 2e-46 158.2 0.4 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 CRK18828.1 - 0.0022 17.6 0.1 0.003 17.1 0.1 1.2 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.11 CRK18828.1 - 0.0023 17.8 0.0 0.0034 17.3 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) Lipase_3 PF01764.25 CRK18828.1 - 0.043 13.7 0.0 0.058 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF2974 PF11187.8 CRK18828.1 - 0.1 12.1 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_2 PF02230.16 CRK18828.1 - 0.21 11.4 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 CRK18829.1 - 7.6e-24 84.7 0.1 1.1e-23 84.2 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 CRK18829.1 - 0.00023 20.2 0.0 0.48 9.2 0.1 2.1 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_6 PF12697.7 CRK18829.1 - 0.001 19.7 0.3 0.0016 19.1 0.3 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Zn_clus PF00172.18 CRK18831.1 - 5.5e-08 32.8 8.5 8.7e-08 32.2 8.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 CRK18831.1 - 1.3e-06 27.6 0.1 4.7e-06 25.8 0.1 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 CRK18831.1 - 0.00018 20.6 9.6 0.00018 20.6 9.6 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily ALMT PF11744.8 CRK18831.1 - 0.045 12.6 2.9 0.11 11.4 2.9 1.5 1 0 0 1 1 1 0 Aluminium activated malate transporter Sugar_tr PF00083.24 CRK18831.1 - 0.34 9.7 6.6 0.54 9.0 6.6 1.2 1 0 0 1 1 1 0 Sugar (and other) transporter DUF4635 PF15466.6 CRK18831.1 - 0.83 9.2 4.0 3.6 7.1 1.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4635) TFIIA PF03153.13 CRK18831.1 - 7.8 6.4 24.1 2.7 7.9 15.8 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit NAD_binding_11 PF14833.6 CRK18832.1 - 5.8e-66 220.3 0.9 2.8e-33 114.7 0.0 2.6 2 0 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 CRK18832.1 - 1.1e-62 210.9 8.1 2.1e-31 109.2 2.2 2.9 3 0 0 3 3 3 2 NAD binding domain of 6-phosphogluconate dehydrogenase SBD_N PF07005.11 CRK18832.1 - 2.1e-59 201.1 0.0 4.6e-59 199.9 0.0 1.6 1 0 0 1 1 1 1 Sugar-binding N-terminal domain NBD_C PF17042.5 CRK18832.1 - 2e-43 148.8 3.3 2.3e-43 148.6 0.9 2.4 2 0 0 2 2 2 1 Nucleotide-binding C-terminal domain 2-Hacid_dh_C PF02826.19 CRK18832.1 - 2.5e-08 33.5 0.0 0.00037 19.9 0.0 2.7 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 CRK18832.1 - 2.9e-06 27.8 5.4 0.0011 19.5 0.2 3.9 3 1 0 3 3 3 2 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh PF00984.19 CRK18832.1 - 0.0011 19.1 0.4 1.7 8.9 0.0 3.0 2 1 0 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, central domain 3HCDH_N PF02737.18 CRK18832.1 - 0.0017 18.3 1.2 0.0017 18.3 1.2 2.8 3 0 0 3 3 3 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 CRK18832.1 - 0.0077 15.9 0.7 0.44 10.2 0.0 2.6 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 CRK18832.1 - 0.57 9.7 3.3 31 4.1 0.6 4.0 3 1 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FSH1 PF03959.13 CRK18833.1 - 4.9e-26 91.7 0.0 6.3e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) KR PF08659.10 CRK18834.1 - 1.2e-80 269.7 7.2 6.3e-63 211.9 0.3 3.2 3 0 0 3 3 3 2 KR domain ketoacyl-synt PF00109.26 CRK18834.1 - 9.9e-70 235.0 0.0 3.1e-69 233.4 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 CRK18834.1 - 3.5e-64 217.3 2.2 6.1e-64 216.5 2.2 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 CRK18834.1 - 3.7e-44 151.2 0.0 6.6e-44 150.3 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 CRK18834.1 - 5e-39 133.0 0.0 1.6e-37 128.1 0.0 3.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.25 CRK18834.1 - 1.4e-19 70.4 5.3 1.3e-16 60.6 0.0 3.9 3 1 1 4 4 3 2 short chain dehydrogenase KAsynt_C_assoc PF16197.5 CRK18834.1 - 2.2e-19 69.9 0.0 9e-19 68.0 0.0 2.1 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N PF00107.26 CRK18834.1 - 9.8e-14 51.4 0.1 5.2e-13 49.1 0.1 2.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CRK18834.1 - 1.7e-13 51.7 0.0 7.8e-13 49.6 0.0 2.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short_C2 PF13561.6 CRK18834.1 - 2.2e-13 50.3 0.7 2.2e-11 43.8 0.0 2.9 3 0 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase PP-binding PF00550.25 CRK18834.1 - 1.5e-07 31.6 0.4 3.9e-07 30.3 0.4 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site SAT PF16073.5 CRK18834.1 - 3.2e-07 30.3 1.6 1.7e-06 28.0 0.7 2.5 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis ADH_N PF08240.12 CRK18834.1 - 3.9e-07 29.9 0.1 1e-06 28.6 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ACP_syn_III PF08545.10 CRK18834.1 - 0.0002 21.1 0.0 0.00066 19.5 0.0 2.0 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Sacchrp_dh_NADP PF03435.18 CRK18834.1 - 0.00028 21.1 0.1 0.046 14.0 0.0 3.1 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Thiolase_N PF00108.23 CRK18834.1 - 0.0025 17.2 0.0 0.007 15.7 0.0 1.7 1 0 0 1 1 1 1 Thiolase, N-terminal domain GDP_Man_Dehyd PF16363.5 CRK18834.1 - 0.012 15.0 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NAD_binding_3 PF03447.16 CRK18834.1 - 0.021 15.4 0.1 0.15 12.7 0.0 2.6 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 CRK18834.1 - 0.095 12.6 0.4 2 8.2 0.0 2.9 2 0 0 2 2 2 0 NAD(P)H-binding Polysacc_synt_2 PF02719.15 CRK18834.1 - 0.14 11.2 0.0 0.27 10.3 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NmrA PF05368.13 CRK18834.1 - 0.18 11.3 1.2 0.68 9.4 0.0 2.4 2 0 0 2 2 2 0 NmrA-like family UPF0253 PF06786.12 CRK18834.1 - 0.83 10.0 2.6 51 4.2 0.3 3.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0253) MFS_1 PF07690.16 CRK18835.1 - 2.3e-45 155.1 48.1 2.8e-45 154.8 44.6 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily SPT_ssu-like PF11779.8 CRK18835.1 - 0.0068 16.0 0.4 0.035 13.7 0.2 2.5 2 0 0 2 2 2 1 Small subunit of serine palmitoyltransferase-like Pex14_N PF04695.13 CRK18835.1 - 0.29 11.8 0.9 38 4.9 0.1 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF412 PF04217.13 CRK18835.1 - 1.6 8.6 5.2 0.8 9.6 1.8 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF412 DUF4133 PF13571.6 CRK18835.1 - 2.5 8.5 0.0 2.5 8.5 0.0 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4133) FeoB_C PF07664.12 CRK18835.1 - 2.7 7.7 5.4 4 7.2 1.2 3.4 2 1 0 2 2 2 0 Ferrous iron transport protein B C terminus Thioredoxin PF00085.20 CRK18837.1 - 2e-25 88.8 0.0 3.5e-25 88.0 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 CRK18837.1 - 2.5e-06 27.6 0.1 3.7e-06 27.0 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.6 CRK18837.1 - 6.8e-06 26.3 0.0 0.00039 20.7 0.0 2.2 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.6 CRK18837.1 - 7.3e-06 26.4 0.1 2.4e-05 24.7 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 CRK18837.1 - 3.4e-05 23.3 0.5 4.5e-05 23.0 0.0 1.5 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 CRK18837.1 - 0.00017 21.5 0.0 0.00033 20.6 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family TraF PF13728.6 CRK18837.1 - 0.00073 19.4 0.0 0.001 18.9 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 CRK18837.1 - 0.0014 18.4 0.0 0.0018 18.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 CRK18837.1 - 0.0019 17.9 0.1 0.0042 16.8 0.1 1.5 1 1 0 1 1 1 1 Redoxin HyaE PF07449.11 CRK18837.1 - 0.003 17.5 0.0 0.0045 16.9 0.0 1.3 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE Thioredoxin_5 PF13743.6 CRK18837.1 - 0.084 12.5 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_3 PF13192.6 CRK18837.1 - 0.098 12.7 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin domain MFS_1 PF07690.16 CRK18838.1 - 4.8e-39 134.3 45.5 3.1e-38 131.6 44.9 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily YchF-GTPase_C PF06071.13 CRK18838.1 - 1.6e-32 111.5 0.0 3.8e-32 110.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 CRK18838.1 - 2.1e-15 56.8 0.0 4.9e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CRK18838.1 - 0.0018 17.8 0.0 0.0035 16.9 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.21 CRK18838.1 - 0.002 18.1 0.0 0.0072 16.4 0.0 2.0 1 0 0 1 1 1 1 TGS domain SPT_ssu-like PF11779.8 CRK18838.1 - 0.035 13.7 0.1 0.14 11.8 0.1 2.1 1 0 0 1 1 1 0 Small subunit of serine palmitoyltransferase-like BetaGal_dom3 PF13363.6 CRK18838.1 - 0.14 11.7 0.0 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 Beta-galactosidase, domain 3 DUF4133 PF13571.6 CRK18838.1 - 1.1 9.6 6.4 5.3 7.4 0.0 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4133) Glyco_hydro_28 PF00295.17 CRK18839.1 - 1.2e-41 142.8 0.0 1.7e-41 142.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Thioredoxin PF00085.20 CRK18839.1 - 4.3e-24 84.5 0.0 7.8e-24 83.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 CRK18839.1 - 3.5e-05 23.9 0.1 7.8e-05 22.8 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 CRK18839.1 - 8.1e-05 23.0 0.0 0.00023 21.6 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CRK18839.1 - 0.00011 22.5 0.0 0.0013 19.0 0.0 2.3 1 1 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 CRK18839.1 - 0.00018 21.0 0.0 0.0003 20.2 0.0 1.3 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 CRK18839.1 - 0.00085 19.2 0.0 0.0016 18.3 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.6 CRK18839.1 - 0.0054 16.5 0.0 0.0091 15.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 CRK18839.1 - 0.016 14.9 0.1 0.044 13.5 0.1 1.6 1 1 0 1 1 1 0 Redoxin TraF PF13728.6 CRK18839.1 - 0.017 14.9 0.0 0.03 14.1 0.0 1.3 1 0 0 1 1 1 0 F plasmid transfer operon protein HyaE PF07449.11 CRK18839.1 - 0.04 13.9 0.0 0.077 13.0 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_5 PF13743.6 CRK18839.1 - 0.13 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin YchF-GTPase_C PF06071.13 CRK18841.1 - 3.1e-33 113.8 0.3 8.6e-33 112.4 0.0 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 CRK18841.1 - 3e-16 59.5 0.0 7.6e-16 58.2 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CRK18841.1 - 0.00044 19.8 0.0 0.00098 18.7 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.21 CRK18841.1 - 0.00067 19.7 0.0 0.0017 18.3 0.0 1.7 1 0 0 1 1 1 1 TGS domain DNA_pol3_a_NII PF11490.8 CRK18841.1 - 0.021 14.7 1.3 0.74 9.7 0.0 2.8 3 0 0 3 3 3 0 DNA polymerase III polC-type N-terminus II BetaGal_dom3 PF13363.6 CRK18841.1 - 0.041 13.5 0.0 0.077 12.6 0.0 1.4 1 0 0 1 1 1 0 Beta-galactosidase, domain 3 AAA_18 PF13238.6 CRK18841.1 - 0.13 12.8 0.4 11 6.6 0.0 3.2 3 1 0 3 3 3 0 AAA domain AAA_14 PF13173.6 CRK18841.1 - 0.13 12.2 0.0 0.55 10.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain MalF_P2 PF14785.6 CRK18841.1 - 0.16 12.0 0.2 0.66 10.0 0.0 1.9 2 0 0 2 2 2 0 Maltose transport system permease protein MalF P2 domain Peptidase_C97 PF05903.14 CRK18842.1 - 1e-36 126.1 0.0 1.2e-36 125.8 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain DUF778 PF05608.12 CRK18842.1 - 0.025 15.0 0.0 0.034 14.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF778) LRAT PF04970.13 CRK18842.1 - 0.068 13.5 0.1 0.11 12.8 0.1 1.3 1 0 0 1 1 1 0 Lecithin retinol acyltransferase Ribosomal_S11 PF00411.19 CRK18843.1 - 3.8e-07 30.5 0.1 9.5e-07 29.2 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S11 Tim44 PF04280.15 CRK18844.1 - 1.4e-35 122.5 0.0 3.7e-35 121.2 0.0 1.7 1 0 0 1 1 1 1 Tim44-like domain CDC45 PF02724.14 CRK18844.1 - 0.48 8.7 23.3 0.86 7.8 6.3 2.1 2 0 0 2 2 2 0 CDC45-like protein FYDLN_acid PF09538.10 CRK18844.1 - 1.4 9.6 16.4 2.5 8.8 3.9 3.0 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Cu_bind_like PF02298.17 CRK18846.1 - 6.3e-05 22.9 0.2 0.00014 21.8 0.2 1.5 1 1 0 1 1 1 1 Plastocyanin-like domain Copper-bind PF00127.20 CRK18846.1 - 0.039 14.4 0.2 0.2 12.1 0.2 2.0 1 1 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family DUF1180 PF06679.12 CRK18846.1 - 1.3 9.4 4.1 0.91 9.9 2.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) MFS_1 PF07690.16 CRK18847.1 - 3.1e-23 82.3 52.4 1.9e-13 50.1 23.4 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily BatA PF07584.11 CRK18847.1 - 0.52 10.7 4.5 7.3 7.0 0.1 3.6 3 0 0 3 3 3 0 Aerotolerance regulator N-terminal DUF624 PF04854.14 CRK18847.1 - 3.3 7.9 11.2 1.4 9.1 1.8 4.0 3 0 0 3 3 3 0 Protein of unknown function, DUF624 SIR2 PF02146.17 CRK18848.1 - 1.4e-23 83.7 0.1 3.8e-16 59.5 0.0 2.1 1 1 1 2 2 2 2 Sir2 family zf-TFIIB PF13453.6 CRK18848.1 - 0.0046 16.2 0.6 0.23 10.8 0.0 2.6 2 0 0 2 2 2 1 Transcription factor zinc-finger DUF1416 PF07210.12 CRK18848.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1416) adh_short_C2 PF13561.6 CRK18850.1 - 1.3e-48 165.6 5.3 8e-46 156.5 5.3 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRK18850.1 - 2e-43 148.2 3.4 2.4e-43 147.9 3.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CRK18850.1 - 7.8e-15 55.2 1.5 1.1e-14 54.7 1.5 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 CRK18850.1 - 0.005 16.7 0.6 0.0074 16.2 0.6 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 CRK18850.1 - 0.041 14.0 0.4 0.078 13.0 0.4 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DUF4081 PF13312.6 CRK18850.1 - 0.13 12.4 0.0 27 5.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4081) Glycos_transf_2 PF00535.26 CRK18851.1 - 4.6e-34 117.7 0.0 5.5e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 CRK18851.1 - 1.7e-12 47.8 0.0 2.1e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 CRK18851.1 - 6.9e-05 22.4 0.0 0.00011 21.7 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.9 CRK18851.1 - 0.00019 21.0 0.0 0.00026 20.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 TMA7 PF09072.10 CRK18853.1 - 5.6e-28 97.6 20.4 6.2e-28 97.4 20.4 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 Pkinase PF00069.25 CRK18855.1 - 1.3e-49 169.0 0.0 1.7e-49 168.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK18855.1 - 3.5e-22 78.9 0.0 7.3e-22 77.9 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase N36 PF11438.8 CRK18855.1 - 0.015 15.0 0.2 0.044 13.6 0.2 1.7 1 0 0 1 1 1 0 36-mer N-terminal peptide of the N protein (N36) Pox_ser-thr_kin PF05445.11 CRK18855.1 - 0.042 12.8 0.1 0.065 12.2 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 CRK18855.1 - 0.058 13.0 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 CRK18855.1 - 0.12 11.7 0.1 0.25 10.7 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Tim44 PF04280.15 CRK18856.1 - 4.1e-36 124.3 0.0 9e-36 123.2 0.0 1.6 2 0 0 2 2 2 1 Tim44-like domain DUF1445 PF07286.12 CRK18856.1 - 0.083 12.8 0.0 0.25 11.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1445) DUF1768 PF08719.11 CRK18857.1 - 3.1e-48 164.0 0.0 3.7e-48 163.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) NTP_transf_9 PF04248.12 CRK18858.1 - 7.6e-06 25.7 0.0 9.8e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF427) Cu_bind_like PF02298.17 CRK18859.1 - 0.00041 20.3 0.1 0.00093 19.2 0.1 1.5 1 1 0 1 1 1 1 Plastocyanin-like domain Copper-bind PF00127.20 CRK18859.1 - 0.017 15.6 0.3 0.1 13.1 0.3 2.0 1 1 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family SAP130_C PF16014.5 CRK18859.1 - 4.6 6.2 17.2 0.55 9.3 2.1 2.0 1 1 0 2 2 2 0 Histone deacetylase complex subunit SAP130 C-terminus MFS_1 PF07690.16 CRK18860.1 - 2.2e-23 82.7 51.9 4.4e-13 48.9 23.8 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily SIR2 PF02146.17 CRK18861.1 - 1.2e-27 97.0 0.2 2e-20 73.4 0.0 2.1 1 1 1 2 2 2 2 Sir2 family adh_short_C2 PF13561.6 CRK18863.1 - 9.7e-48 162.7 6.9 4.5e-45 154.0 6.9 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRK18863.1 - 1.2e-43 148.8 4.0 1.5e-43 148.5 4.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CRK18863.1 - 9.2e-15 55.0 1.6 1.3e-14 54.5 1.6 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 CRK18863.1 - 0.0054 16.6 0.7 0.0083 16.0 0.7 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 CRK18863.1 - 0.041 14.0 0.4 0.078 13.0 0.4 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Glycos_transf_2 PF00535.26 CRK18864.1 - 2e-33 115.6 0.0 2.4e-33 115.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 CRK18864.1 - 1.9e-12 47.6 0.0 2.4e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 CRK18864.1 - 7.3e-05 22.3 0.0 0.00012 21.6 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.9 CRK18864.1 - 0.00022 20.8 0.0 0.0003 20.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 TMA7 PF09072.10 CRK18865.1 - 5.6e-28 97.6 20.4 6.2e-28 97.4 20.4 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 Pkinase PF00069.25 CRK18866.1 - 1.3e-49 169.0 0.0 1.7e-49 168.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK18866.1 - 3.5e-22 78.9 0.0 7.3e-22 77.9 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase N36 PF11438.8 CRK18866.1 - 0.016 15.0 0.2 0.044 13.6 0.2 1.7 1 0 0 1 1 1 0 36-mer N-terminal peptide of the N protein (N36) Pox_ser-thr_kin PF05445.11 CRK18866.1 - 0.042 12.8 0.1 0.065 12.2 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 CRK18866.1 - 0.058 13.0 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 CRK18866.1 - 0.13 11.6 0.1 0.25 10.7 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 CRK18868.1 - 6.8e-55 186.3 0.0 8.8e-55 185.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK18868.1 - 4.5e-32 111.3 0.0 5.9e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CRK18868.1 - 5.6e-05 22.6 0.0 0.00061 19.2 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 CRK18868.1 - 0.0037 17.2 0.1 0.0093 15.9 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 CRK18868.1 - 0.0048 16.3 0.0 0.0077 15.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CRK18868.1 - 0.028 13.4 0.0 0.044 12.7 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 CRK18868.1 - 0.055 13.1 0.0 0.53 9.9 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 CRK18868.1 - 0.066 12.0 0.0 0.091 11.5 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Apt1 PF10351.9 CRK18870.1 - 0.085 11.7 0.9 0.12 11.2 0.9 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain GvpL_GvpF PF06386.11 CRK18870.1 - 0.16 11.8 1.1 0.29 11.0 1.1 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF zf-H2C2_5 PF13909.6 CRK18871.1 - 0.0037 17.0 9.7 0.065 13.0 1.3 3.9 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-Di19 PF05605.12 CRK18871.1 - 0.11 12.8 16.5 0.15 12.4 3.0 3.8 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 CRK18871.1 - 1.5 9.9 34.5 4.7 8.3 0.3 8.0 7 0 0 7 7 7 0 C2H2-type zinc finger AATase PF07247.12 CRK18873.1 - 4e-14 52.1 0.0 5.3e-12 45.1 0.0 2.7 2 1 0 2 2 2 2 Alcohol acetyltransferase WES_acyltransf PF03007.16 CRK18873.1 - 0.0043 16.9 0.0 0.0087 15.8 0.0 1.5 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain Condensation PF00668.20 CRK18873.1 - 0.043 12.5 0.0 0.1 11.2 0.0 1.5 2 0 0 2 2 2 0 Condensation domain RSN1_7TM PF02714.15 CRK18874.1 - 8.6e-78 261.4 17.5 1.3e-77 260.8 17.5 1.3 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 CRK18874.1 - 2.9e-39 135.1 0.0 4.8e-39 134.4 0.0 1.4 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 CRK18874.1 - 1.8e-37 128.5 3.3 3.7e-37 127.5 3.3 1.6 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport HET PF06985.11 CRK18874.1 - 1.8e-25 90.0 0.0 3.7e-25 89.0 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TMF_TATA_bd PF12325.8 CRK18874.1 - 0.25 11.6 0.2 0.51 10.6 0.2 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Histidinol_dh PF00815.20 CRK18875.1 - 1.9e-136 455.3 0.0 2.3e-136 455.0 0.0 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase BTB PF00651.31 CRK18876.1 - 1.9e-05 24.9 0.1 4.4e-05 23.7 0.1 1.6 1 0 0 1 1 1 1 BTB/POZ domain Inhibitor_I78 PF11720.8 CRK18878.1 - 2.1e-09 37.3 0.0 3.4e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.18 CRK18878.1 - 0.0013 19.4 0.1 0.0025 18.5 0.1 1.5 1 0 0 1 1 1 1 Potato inhibitor I family DUF2924 PF11149.8 CRK18878.1 - 0.12 12.8 0.0 0.14 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2924) TMEM100 PF16311.5 CRK18879.1 - 0.061 12.9 0.4 0.061 12.9 0.4 1.7 2 0 0 2 2 2 0 Transmembrane protein 100 MFS_1 PF07690.16 CRK18880.1 - 3.4e-12 46.0 21.5 3.9e-12 45.8 21.0 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 CRK18880.1 - 3.2e-07 30.2 2.1 3.2e-07 30.2 2.1 1.6 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 JAKMIP_CC3 PF16034.5 CRK18881.1 - 0.082 12.8 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 JAKMIP CC3 domain Peptidase_M36 PF02128.15 CRK18883.1 - 1.6e-146 488.3 6.7 2.4e-146 487.7 6.7 1.3 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 CRK18883.1 - 1.2e-18 66.7 5.4 2.7e-18 65.5 5.4 1.7 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.15 CRK18883.1 - 0.00021 21.2 0.4 0.0013 18.6 0.0 2.1 2 0 0 2 2 2 1 Thermolysin metallopeptidase, alpha-helical domain VPS9 PF02204.18 CRK18884.1 - 1.7e-19 70.0 0.1 4e-19 68.7 0.1 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_5 PF13857.6 CRK18884.1 - 5.2e-19 68.1 0.3 4.7e-13 49.1 0.0 4.8 5 1 1 6 6 6 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CRK18884.1 - 2.7e-12 47.1 0.0 9.4e-05 22.9 0.0 3.9 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CRK18884.1 - 1.4e-08 35.1 0.2 0.11 13.1 0.0 5.2 5 1 0 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CRK18884.1 - 8.9e-07 28.8 0.7 0.38 11.5 0.0 5.4 6 0 0 6 6 6 2 Ankyrin repeat Ank PF00023.30 CRK18884.1 - 0.0031 17.9 0.0 3.2 8.3 0.0 4.1 4 0 0 4 4 4 1 Ankyrin repeat APH PF01636.23 CRK18887.1 - 1.4e-13 51.4 0.0 1.7e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CRK18887.1 - 0.17 10.8 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Choline_kinase PF01633.20 CRK18887.1 - 0.17 11.5 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase GATase PF00117.28 CRK18894.1 - 4.3e-48 163.6 0.0 5.2e-48 163.3 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 CRK18894.1 - 5.3e-07 29.6 0.0 1.6e-06 28.1 0.0 1.7 1 1 0 1 1 1 1 Peptidase C26 Ank_5 PF13857.6 CRK18895.1 - 3.7e-21 74.9 3.9 1.7e-08 34.5 0.4 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 CRK18895.1 - 8.6e-20 70.8 7.0 3e-07 30.8 0.1 3.5 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 CRK18895.1 - 9.9e-16 58.1 3.2 1.8e-13 50.9 0.6 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CRK18895.1 - 2.5e-12 45.8 0.5 0.0024 18.2 0.0 3.8 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 CRK18895.1 - 4.7e-10 39.4 2.5 0.0045 17.4 0.1 3.4 3 0 0 3 3 3 3 Ankyrin repeat TMF_TATA_bd PF12325.8 CRK18896.1 - 2.7e-40 137.2 8.1 2.7e-40 137.2 8.1 6.3 2 1 4 6 6 6 2 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 CRK18896.1 - 3.3e-13 49.4 6.3 3.3e-13 49.4 6.3 7.6 6 3 1 7 7 7 1 TATA element modulatory factor 1 DNA binding ATG16 PF08614.11 CRK18896.1 - 0.0061 16.8 5.8 0.0061 16.8 5.8 5.9 2 1 3 5 5 5 2 Autophagy protein 16 (ATG16) Holin_BhlA PF10960.8 CRK18896.1 - 0.065 13.2 0.3 0.4 10.7 0.3 2.4 1 0 0 1 1 1 0 BhlA holin family Prefoldin_2 PF01920.20 CRK18897.1 - 3.1e-17 62.5 3.7 3.7e-17 62.2 3.7 1.2 1 0 0 1 1 1 1 Prefoldin subunit TMF_TATA_bd PF12325.8 CRK18897.1 - 0.0015 18.7 2.6 0.016 15.4 0.1 2.1 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding DUF641 PF04859.12 CRK18897.1 - 0.0081 16.5 1.6 0.22 11.8 0.2 2.2 2 0 0 2 2 2 1 Plant protein of unknown function (DUF641) DUF16 PF01519.16 CRK18897.1 - 0.037 14.5 2.5 0.096 13.2 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF2730 PF10805.8 CRK18897.1 - 0.053 13.6 3.5 3.5 7.8 0.2 2.7 1 1 1 3 3 3 0 Protein of unknown function (DUF2730) DUF4200 PF13863.6 CRK18897.1 - 0.064 13.7 7.8 0.2 12.0 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Tup_N PF08581.10 CRK18897.1 - 0.3 11.4 4.0 0.51 10.7 0.3 2.1 2 0 0 2 2 2 0 Tup N-terminal CENP-H PF05837.12 CRK18897.1 - 0.33 11.4 4.8 2.1 8.8 0.3 2.1 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DUF3450 PF11932.8 CRK18897.1 - 0.36 10.1 6.1 2.2 7.5 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) HR1 PF02185.16 CRK18897.1 - 0.47 10.6 8.6 12 6.1 4.3 2.8 1 1 2 3 3 3 0 Hr1 repeat DUF2681 PF10883.8 CRK18897.1 - 0.48 10.9 6.2 0.34 11.4 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Fib_alpha PF08702.10 CRK18897.1 - 0.52 10.5 4.8 0.73 10.0 0.3 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family IFT20 PF14931.6 CRK18897.1 - 0.93 9.7 7.5 0.25 11.5 0.8 2.1 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 TMF_DNA_bd PF12329.8 CRK18897.1 - 1.5 8.9 9.5 0.13 12.2 2.2 2.2 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding OmpH PF03938.14 CRK18897.1 - 1.5 9.1 9.8 0.44 10.9 0.9 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) XhlA PF10779.9 CRK18897.1 - 1.7 8.9 4.1 0.88 9.8 1.4 1.8 2 0 0 2 2 2 0 Haemolysin XhlA Ceramidase PF05875.12 CRK18898.1 - 1.5e-61 208.2 5.1 2.1e-61 207.6 5.1 1.2 1 0 0 1 1 1 1 Ceramidase DUF4817 PF16087.5 CRK18898.1 - 2.2e-05 24.1 0.1 0.46 10.3 0.0 3.0 2 0 0 2 2 2 2 Helix-turn-helix domain (DUF4817) FAD_binding_7 PF03441.14 CRK18898.1 - 0.03 13.8 0.5 8.2 5.8 0.1 2.7 2 0 0 2 2 2 0 FAD binding domain of DNA photolyase ECF_trnsprt PF12822.7 CRK18898.1 - 0.86 9.7 3.6 2 8.5 2.1 1.9 2 0 0 2 2 2 0 ECF transporter, substrate-specific component Mito_carr PF00153.27 CRK18899.1 - 7e-50 166.9 1.7 1.2e-17 63.6 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.27 CRK18900.1 - 3.5e-50 167.9 1.2 1.2e-17 63.6 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein TRAM_LAG1_CLN8 PF03798.16 CRK18901.1 - 2.3e-51 174.3 12.9 3.1e-51 174.0 12.9 1.1 1 0 0 1 1 1 1 TLC domain A_deaminase PF00962.22 CRK18902.1 - 7e-122 406.9 0.1 1.1e-121 406.2 0.1 1.4 1 0 0 1 1 1 1 Adenosine/AMP deaminase SH3_9 PF14604.6 CRK18902.1 - 5.5e-43 144.6 14.6 8e-12 44.8 0.2 4.7 4 0 0 4 4 4 4 Variant SH3 domain SH3_1 PF00018.28 CRK18902.1 - 2.2e-41 139.2 7.6 5.2e-13 48.4 0.1 5.3 5 0 0 5 5 5 4 SH3 domain SHD1 PF03983.12 CRK18902.1 - 3.9e-33 113.1 0.0 8.3e-33 112.0 0.0 1.5 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_2 PF07653.17 CRK18902.1 - 4.9e-23 80.6 0.1 2e-05 24.2 0.1 5.5 5 0 0 5 5 5 4 Variant SH3 domain DUF1720 PF08226.11 CRK18902.1 - 4.4e-10 39.8 26.6 4.4e-10 39.8 26.6 6.1 1 1 4 5 5 3 2 Domain of unknown function (DUF1720) SH3_3 PF08239.11 CRK18902.1 - 1.1e-07 32.0 5.4 0.029 14.6 0.4 4.1 4 0 0 4 4 4 2 Bacterial SH3 domain SH3_10 PF17902.1 CRK18902.1 - 1.8e-05 24.7 0.0 0.44 10.7 0.0 2.9 2 0 0 2 2 2 2 SH3 domain SAM_4 PF18017.1 CRK18902.1 - 0.00026 20.9 0.0 0.001 19.0 0.0 2.0 2 0 0 2 2 1 1 SAM domain (Sterile alpha motif) DUF1798 PF08807.10 CRK18902.1 - 0.01 16.0 0.2 14 5.9 0.0 3.3 3 0 0 3 3 3 0 Bacterial domain of unknown function (DUF1798) SIN1_PH PF16979.5 CRK18902.1 - 0.047 14.0 0.4 26 5.1 0.0 3.2 2 2 0 2 2 2 0 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology PA14 PF07691.12 CRK18902.1 - 0.1 12.4 0.4 26 4.6 0.0 2.9 3 0 0 3 3 3 0 PA14 domain MMgT PF10270.9 CRK18904.1 - 6e-35 119.6 0.0 1.4e-34 118.4 0.0 1.7 1 0 0 1 1 1 1 Membrane magnesium transporter HMG_box PF00505.19 CRK18904.1 - 1.1e-11 44.9 0.3 3.1e-10 40.3 0.0 3.2 3 0 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CRK18904.1 - 0.0039 17.8 0.0 0.0039 17.8 0.0 2.5 2 0 0 2 2 2 1 HMG-box domain MATalpha_HMGbox PF04769.12 CRK18904.1 - 0.019 14.3 0.0 0.038 13.3 0.0 1.4 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box APH PF01636.23 CRK18904.1 - 3.6 7.4 6.9 22 4.9 6.8 2.2 1 1 0 1 1 1 0 Phosphotransferase enzyme family Ion_trans PF00520.31 CRK18906.1 - 3.2e-110 367.1 73.0 3.6e-44 150.8 5.5 5.0 4 2 0 4 4 4 4 Ion transport protein JSRP PF15312.6 CRK18906.1 - 0.019 14.9 0.0 0.067 13.1 0.0 1.9 1 0 0 1 1 1 0 Junctional sarcoplasmic reticulum protein Ribosomal_L2_C PF03947.18 CRK18909.1 - 1.5e-50 170.6 3.3 3.5e-50 169.4 3.3 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 CRK18909.1 - 8.2e-13 48.1 0.1 2.5e-12 46.6 0.0 1.8 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain Cyclin_N PF00134.23 CRK18910.1 - 3.2e-43 146.5 0.1 1.9e-42 144.0 0.0 2.3 3 0 0 3 3 3 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CRK18910.1 - 2.8e-32 111.3 0.0 5.9e-32 110.2 0.0 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain PAP2 PF01569.21 CRK18910.1 - 1.3e-21 76.8 0.6 5.3e-21 74.8 0.6 2.1 1 1 0 1 1 1 1 PAP2 superfamily DUF2142 PF09913.9 CRK18910.1 - 0.15 10.9 3.1 3.6 6.3 0.2 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2142) CK_II_beta PF01214.18 CRK18911.1 - 1.6e-77 259.4 0.2 2.1e-77 259.1 0.2 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit WD40 PF00400.32 CRK18912.1 - 9.4e-11 42.1 2.0 9.9e-06 26.2 1.1 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK18912.1 - 0.0038 17.5 0.1 4.1 7.8 0.0 2.7 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Metallophos_2 PF12850.7 CRK18913.1 - 4.2e-07 30.3 0.0 5.6e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Mito_carr PF00153.27 CRK18915.1 - 5.6e-14 51.8 0.1 2.3e-13 49.8 0.0 1.8 2 0 0 2 2 2 1 Mitochondrial carrier protein Cytochrom_B562 PF07361.11 CRK18915.1 - 0.11 13.2 1.3 0.25 12.0 0.3 2.0 1 1 1 2 2 2 0 Cytochrome b562 Talin_middle PF09141.10 CRK18915.1 - 0.18 11.8 2.2 0.42 10.6 1.8 1.7 1 1 1 2 2 2 0 Talin, middle domain Trp_syntA PF00290.20 CRK18928.1 - 5.5e-61 205.7 0.0 7.2e-61 205.3 0.0 1.1 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PRO8NT PF08082.11 CRK18954.1 - 9.6e-28 97.0 0.3 1.4e-27 96.5 0.3 1.2 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain DUF45 PF01863.17 CRK18954.1 - 0.1 12.7 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF45 Hemerythrin PF01814.23 CRK18955.1 - 1.7e-12 48.1 0.6 1.9e-12 47.9 0.6 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Clathrin_propel PF01394.20 CRK18961.1 - 2.3e-07 30.8 0.0 0.0029 17.9 0.0 2.4 2 0 0 2 2 2 2 Clathrin propeller repeat PQQ_2 PF13360.6 CRK18961.1 - 0.0012 18.5 0.1 0.0026 17.4 0.1 1.6 2 0 0 2 2 2 1 PQQ-like domain SdrG_C_C PF10425.9 CRK18961.1 - 0.11 12.5 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 C-terminus of bacterial fibrinogen-binding adhesin E1_dh PF00676.20 CRK18962.1 - 7.1e-42 143.4 0.0 7.9e-42 143.2 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component YceG_bac PF14266.6 CRK18962.1 - 0.012 14.6 0.1 0.015 14.2 0.1 1.1 1 0 0 1 1 1 0 Putative component of 'biosynthetic module' AMP-binding PF00501.28 CRK18965.1 - 0.0016 17.1 0.0 0.002 16.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PBP_like PF12727.7 CRK18965.1 - 0.0098 15.0 0.0 0.013 14.6 0.0 1.1 1 0 0 1 1 1 1 PBP superfamily domain PI-PLC-C1 PF16670.5 CRK18967.1 - 1.7e-123 411.9 0.0 1.9e-123 411.8 0.0 1.0 1 0 0 1 1 1 1 Phosphoinositide phospholipase C, Ca2+-dependent WD40 PF00400.32 CRK18968.1 - 1.7e-40 136.3 19.1 1.1e-05 26.1 0.7 7.8 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box PF00646.33 CRK18968.1 - 1.7e-10 40.5 0.2 6e-10 38.8 0.1 2.0 2 1 0 2 2 2 1 F-box domain F-box-like PF12937.7 CRK18968.1 - 3e-10 39.8 0.1 6.4e-10 38.8 0.1 1.6 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 CRK18968.1 - 4.6e-08 33.2 0.6 0.66 10.3 0.0 5.3 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 CRK18968.1 - 0.0052 16.4 1.3 1.8 8.1 0.0 2.9 2 1 0 2 2 2 2 PQQ-like domain F-box_4 PF15966.5 CRK18968.1 - 0.016 15.1 0.0 0.052 13.4 0.0 1.9 1 0 0 1 1 1 0 F-box Nup160 PF11715.8 CRK18968.1 - 0.063 11.9 3.5 17 3.9 0.1 4.4 2 1 2 5 5 5 0 Nucleoporin Nup120/160 GMC_oxred_N PF00732.19 CRK18970.1 - 4.9e-52 177.1 0.0 6.9e-52 176.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CRK18970.1 - 8.3e-33 113.9 0.1 1.4e-32 113.2 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 CRK18970.1 - 0.0054 15.9 0.1 0.24 10.4 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 CRK18970.1 - 0.0073 15.9 0.1 0.18 11.4 0.0 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 CRK18970.1 - 0.011 14.8 0.0 0.018 14.1 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_8 PF13450.6 CRK18970.1 - 0.013 15.8 0.2 0.034 14.4 0.2 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CRK18970.1 - 0.077 12.2 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DLH PF01738.18 CRK18971.1 - 1.7e-28 99.6 0.8 2e-28 99.5 0.8 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family DUF915 PF06028.11 CRK18971.1 - 0.12 11.7 0.1 2.9 7.2 0.1 2.1 1 1 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) DUF747 PF05346.11 CRK18972.1 - 1.1e-118 396.3 6.7 1.4e-118 396.0 6.7 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family TrbL PF04610.14 CRK18972.1 - 0.0037 17.0 1.4 0.007 16.1 1.4 1.4 1 0 0 1 1 1 1 TrbL/VirB6 plasmid conjugal transfer protein Iso_dh PF00180.20 CRK18973.1 - 2e-107 359.4 0.0 2.3e-107 359.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase adh_short_C2 PF13561.6 CRK18974.1 - 4.7e-61 206.3 0.0 5.7e-61 206.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRK18974.1 - 3.2e-48 163.8 0.1 4.1e-48 163.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CRK18974.1 - 1.3e-08 34.9 0.0 2.6e-08 34.0 0.0 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 CRK18974.1 - 0.00037 20.0 0.2 0.00088 18.8 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_3 PF03447.16 CRK18974.1 - 0.018 15.7 0.2 0.1 13.3 0.2 1.9 1 1 1 2 2 2 0 Homoserine dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 CRK18974.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 CRK18974.1 - 0.14 12.1 0.1 0.2 11.5 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Cyclase PF04199.13 CRK18975.1 - 3.3e-11 43.6 0.0 4.1e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase DUF5490 PF17593.2 CRK18975.1 - 0.058 13.4 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5490) Nuc_deoxyri_tr2 PF15891.5 CRK18976.1 - 2.4e-32 111.5 0.0 3.6e-32 110.9 0.0 1.2 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase like Nuc_deoxyrib_tr PF05014.15 CRK18976.1 - 3.7e-05 23.8 0.0 4.6e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Nucleoside 2-deoxyribosyltransferase Asparaginase_2 PF01112.18 CRK18977.1 - 1.3e-49 168.9 0.3 4.4e-46 157.3 0.0 3.2 2 1 0 2 2 2 2 Asparaginase Peptidase_M20 PF01546.28 CRK18977.1 - 6.2e-22 78.3 0.0 1.5e-21 77.0 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 WD40 PF00400.32 CRK18977.1 - 3.1e-05 24.6 4.3 3 8.9 0.1 5.6 5 0 0 5 5 5 2 WD domain, G-beta repeat M20_dimer PF07687.14 CRK18977.1 - 0.0015 18.4 0.0 0.005 16.7 0.0 2.0 1 0 0 1 1 1 1 Peptidase dimerisation domain ANAPC4_WD40 PF12894.7 CRK18977.1 - 0.0016 18.7 0.2 10 6.5 0.0 3.7 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CRK18977.1 - 0.072 12.0 0.1 0.17 10.8 0.1 1.5 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Tim17 PF02466.19 CRK18978.1 - 2.6e-31 108.3 7.5 3.4e-31 107.9 7.5 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family K_oxygenase PF13434.6 CRK18979.1 - 1.7e-108 362.8 0.0 9.9e-108 360.3 0.0 2.0 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) IF-2B PF01008.17 CRK18979.1 - 2e-19 69.9 0.0 3e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 Initiation factor 2 subunit family Pyr_redox_2 PF07992.14 CRK18979.1 - 3.3e-08 33.1 0.0 5.3e-07 29.2 0.0 2.6 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NUDIX PF00293.28 CRK18979.1 - 1.5e-06 28.3 0.0 3.7e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain Pyr_redox_3 PF13738.6 CRK18979.1 - 2.9e-06 26.7 0.0 1.2e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CRK18979.1 - 0.0029 17.6 0.0 0.029 14.4 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding DUF4147 PF13660.6 CRK18979.1 - 0.069 12.7 0.0 4.6 6.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4147) DUF2842 PF11003.8 CRK18980.1 - 1.5 9.1 9.5 6.4 7.1 0.7 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2842) PAP2 PF01569.21 CRK18981.1 - 3.9e-26 91.4 1.0 3.9e-26 91.4 1.0 2.1 2 0 0 2 2 2 1 PAP2 superfamily HisKA_7TM PF16927.5 CRK18981.1 - 0.026 14.6 9.4 0.031 14.3 4.1 2.5 2 1 1 3 3 3 0 N-terminal 7TM region of histidine kinase Proteasome PF00227.26 CRK18982.1 - 8.9e-61 204.7 0.1 1.1e-60 204.4 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CRK18982.1 - 2.7e-13 49.3 0.1 8.7e-13 47.7 0.1 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF5624 PF18538.1 CRK18982.1 - 0.014 15.5 0.6 0.033 14.3 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5624) Nitrate_red_gam PF02665.14 CRK18982.1 - 0.062 12.8 0.0 0.087 12.3 0.0 1.1 1 0 0 1 1 1 0 Nitrate reductase gamma subunit SPOC PF07744.13 CRK18984.1 - 2.6e-25 89.1 0.0 4.1e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 SPOC domain PHD PF00628.29 CRK18984.1 - 1e-08 34.9 10.3 1.9e-08 34.1 10.3 1.5 1 0 0 1 1 1 1 PHD-finger zf-CW PF07496.15 CRK18984.1 - 0.16 12.0 3.5 0.34 11.0 3.5 1.5 1 0 0 1 1 1 0 CW-type Zinc Finger PHD_2 PF13831.6 CRK18984.1 - 0.21 11.2 5.9 0.37 10.4 5.9 1.4 1 0 0 1 1 1 0 PHD-finger zf-UDP PF14569.6 CRK18984.1 - 0.26 11.4 2.6 0.39 10.9 1.1 2.1 2 0 0 2 2 2 0 Zinc-binding RING-finger Med7 PF05983.11 CRK18985.1 - 2.8e-58 197.2 0.0 3.3e-58 196.9 0.0 1.1 1 0 0 1 1 1 1 MED7 protein OrsD PF12013.8 CRK18986.1 - 0.0095 16.4 0.4 0.0095 16.4 0.4 2.6 3 0 0 3 3 3 1 Orsellinic acid/F9775 biosynthesis cluster protein D FAM76 PF16046.5 CRK18986.1 - 0.029 13.7 5.0 0.042 13.2 5.0 1.2 1 0 0 1 1 1 0 FAM76 protein DUF1677 PF07911.13 CRK18986.1 - 0.044 14.2 0.5 0.17 12.3 0.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1677) zf-C2H2_2 PF12756.7 CRK18986.1 - 0.093 13.1 0.1 0.17 12.2 0.1 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) DUF913 PF06025.12 CRK18986.1 - 0.97 8.3 3.8 1.4 7.8 3.8 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CDC45 PF02724.14 CRK18986.1 - 2.9 6.1 8.4 4.3 5.5 8.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.7 CRK18986.1 - 3.3 5.7 4.6 4.5 5.3 4.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Presenilin PF01080.17 CRK18986.1 - 4.8 5.8 7.5 6.5 5.4 7.5 1.1 1 0 0 1 1 1 0 Presenilin F-box-like PF12937.7 CRK18987.1 - 0.0012 18.7 0.1 0.0019 18.0 0.1 1.3 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CRK18987.1 - 0.0044 16.9 0.2 0.0073 16.2 0.2 1.4 1 0 0 1 1 1 1 F-box domain PRANC PF09372.10 CRK18987.1 - 0.24 11.7 0.0 0.33 11.3 0.0 1.1 1 0 0 1 1 1 0 PRANC domain TFIIA PF03153.13 CRK18988.1 - 0.9 9.5 13.4 1.3 9.0 13.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hamartin PF04388.12 CRK18988.1 - 4.5 5.8 12.5 5.7 5.5 12.5 1.1 1 0 0 1 1 1 0 Hamartin protein LUC7 PF03194.15 CRK18989.1 - 6.9e-70 235.6 0.8 8.3e-70 235.3 0.8 1.0 1 0 0 1 1 1 1 LUC7 N_terminus Imm49 PF15575.6 CRK18989.1 - 0.02 14.6 0.1 0.04 13.7 0.1 1.4 1 0 0 1 1 1 0 Immunity protein 49 DUF1241 PF06840.11 CRK18989.1 - 0.052 13.2 0.1 0.11 12.2 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1241) T4SS PF07996.11 CRK18989.1 - 0.13 12.7 0.1 0.13 12.7 0.1 1.4 2 0 0 2 2 2 0 Type IV secretion system proteins Gpi16 PF04113.14 CRK18990.1 - 2.9e-241 801.8 0.0 3.6e-241 801.5 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component adh_short_C2 PF13561.6 CRK18991.1 - 2.3e-53 181.1 0.4 3.7e-53 180.5 0.4 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRK18991.1 - 8.7e-48 162.4 1.0 1.2e-47 161.9 1.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CRK18991.1 - 4e-12 46.4 1.9 6.9e-12 45.6 1.9 1.3 1 0 0 1 1 1 1 KR domain Fungal_trans PF04082.18 CRK18991.1 - 4.1e-11 42.4 0.1 7.9e-11 41.5 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Epimerase PF01370.21 CRK18991.1 - 0.15 11.5 0.2 2.2 7.7 0.2 2.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family PLA2_B PF01735.18 CRK18992.1 - 2.9e-05 22.7 0.0 3.3e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Sugar_tr PF00083.24 CRK18993.1 - 7.6e-25 87.7 11.7 8.6e-25 87.5 11.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK18993.1 - 1.1e-07 31.1 10.7 1.4e-07 30.8 10.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_5 PF05631.14 CRK18993.1 - 0.0099 14.8 1.6 0.013 14.4 1.6 1.1 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM DUF3684 PF12449.8 CRK19001.1 - 9.3e-46 156.2 2.6 1.1e-45 156.0 2.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) Sec16 PF12932.7 CRK19001.1 - 1.4e-07 32.1 1.1 2.4e-07 31.4 0.8 1.8 1 1 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region Striatin PF08232.12 CRK19017.1 - 5.1e-21 75.9 7.2 5.7e-21 75.7 7.2 1.1 1 0 0 1 1 1 1 Striatin family MBA1 PF07961.11 CRK19017.1 - 0.011 14.8 0.0 0.014 14.5 0.0 1.0 1 0 0 1 1 1 0 MBA1-like protein Pho88 PF10032.9 CRK19019.1 - 1.7e-24 86.1 0.0 1.9e-24 85.9 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) Thioredoxin PF00085.20 CRK19026.1 - 5.7e-27 93.7 0.3 8.7e-27 93.1 0.3 1.3 1 0 0 1 1 1 1 Thioredoxin zf-rbx1 PF12678.7 CRK19026.1 - 1.9e-10 40.8 1.0 1.9e-10 40.8 1.0 1.7 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CRK19026.1 - 1e-09 38.1 1.0 2.4e-09 36.9 1.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CRK19026.1 - 2.6e-09 37.3 9.5 8.9e-09 35.5 2.5 2.8 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 CRK19026.1 - 2.1e-07 30.8 2.3 2.1e-07 30.8 2.3 2.3 2 1 1 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CRK19026.1 - 4.6e-07 29.6 7.0 9.7e-07 28.5 2.2 2.6 3 0 0 3 3 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CRK19026.1 - 8.3e-07 28.9 8.5 2.2e-06 27.6 2.0 3.7 2 1 1 3 3 3 1 RING-type zinc-finger Thioredoxin_2 PF13098.6 CRK19026.1 - 2.9e-06 27.7 0.1 6.7e-06 26.5 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain zf-RING_11 PF17123.5 CRK19026.1 - 4e-06 26.5 8.9 0.00062 19.4 0.2 4.0 4 0 0 4 4 4 2 RING-like zinc finger zf-C3HC4_3 PF13920.6 CRK19026.1 - 1.2e-05 25.0 1.3 1.2e-05 25.0 1.3 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CRK19026.1 - 1.6e-05 24.6 0.6 1.6e-05 24.6 0.6 2.3 3 0 0 3 3 2 1 Prokaryotic RING finger family 4 Thioredoxin_8 PF13905.6 CRK19026.1 - 9.5e-05 22.7 0.0 0.00061 20.1 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 CRK19026.1 - 0.00034 20.1 0.0 0.00047 19.6 0.0 1.3 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Zn_ribbon_17 PF17120.5 CRK19026.1 - 0.0015 18.1 0.4 0.0015 18.1 0.4 2.2 3 0 0 3 3 3 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 CRK19026.1 - 0.0053 16.8 0.6 0.0053 16.8 0.6 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger AhpC-TSA PF00578.21 CRK19026.1 - 0.013 15.4 0.2 0.029 14.3 0.1 1.7 2 0 0 2 2 2 0 AhpC/TSA family Thioredoxin_7 PF13899.6 CRK19026.1 - 0.015 15.4 0.0 0.026 14.7 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like HyaE PF07449.11 CRK19026.1 - 0.027 14.4 0.0 0.044 13.7 0.0 1.5 1 1 0 1 1 1 0 Hydrogenase-1 expression protein HyaE TraF PF13728.6 CRK19026.1 - 0.15 11.9 0.0 0.51 10.1 0.0 1.7 2 0 0 2 2 2 0 F plasmid transfer operon protein FANCL_C PF11793.8 CRK19026.1 - 0.72 10.1 8.5 17 5.7 8.1 2.9 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 CRK19026.1 - 1.5 9.0 6.7 0.26 11.5 1.0 2.3 2 0 0 2 2 2 0 RING-variant domain Dus PF01207.17 CRK19030.1 - 1.3e-22 80.3 0.0 1.5e-22 80.1 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-GRF PF06839.12 CRK19033.1 - 0.00019 21.5 4.2 0.00054 20.0 4.2 1.8 1 1 0 1 1 1 1 GRF zinc finger DUF1180 PF06679.12 CRK19033.1 - 0.52 10.7 6.9 0.72 10.2 6.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) HMG_box PF00505.19 CRK19036.1 - 2.2e-13 50.4 2.7 3.4e-13 49.8 2.7 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box Glyco_tran_WecB PF03808.13 CRK19036.1 - 0.11 12.4 0.0 0.26 11.2 0.0 1.6 1 1 1 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family MATalpha_HMGbox PF04769.12 CRK19038.1 - 1.3e-47 161.7 0.0 1.8e-47 161.3 0.0 1.2 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG-box ANTH PF07651.16 CRK19039.1 - 3.2e-81 272.3 0.0 3.2e-81 272.3 0.0 2.5 2 1 0 2 2 2 1 ANTH domain I_LWEQ PF01608.17 CRK19039.1 - 9.4e-54 181.8 10.8 9.4e-54 181.8 10.8 5.6 4 2 2 6 6 6 2 I/LWEQ domain DUF4618 PF15397.6 CRK19039.1 - 0.008 15.6 1.0 0.008 15.6 1.0 4.6 2 1 2 4 4 4 1 Domain of unknown function (DUF4618) Ribosomal_L21e PF01157.18 CRK19040.1 - 4e-42 142.2 3.7 6.3e-42 141.5 3.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L21e NaeI PF09126.10 CRK19040.1 - 0.074 12.2 0.2 0.11 11.7 0.2 1.2 1 0 0 1 1 1 0 Restriction endonuclease NaeI S4 PF01479.25 CRK19041.1 - 3.2e-12 46.0 0.9 3.2e-12 46.0 0.9 2.5 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 CRK19041.1 - 7.4e-06 26.8 0.1 1.3e-05 26.0 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Uds1 PF15456.6 CRK19041.1 - 0.094 12.9 0.7 2.2 8.5 0.0 2.2 2 0 0 2 2 2 0 Up-regulated During Septation DNA_pol_B PF00136.21 CRK19042.1 - 2.6e-68 230.8 0.0 3.7e-68 230.3 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 CRK19042.1 - 4e-20 72.2 0.0 4e-11 42.7 0.0 2.2 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain PH_5 PF15405.6 CRK19042.1 - 0.049 13.7 0.1 0.11 12.5 0.1 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain XkdW PF09636.10 CRK19042.1 - 0.2 11.8 0.7 0.72 10.0 0.2 2.1 2 0 0 2 2 2 0 XkdW protein DNA_pol_B PF00136.21 CRK19043.1 - 5.6e-23 81.4 0.0 8.3e-23 80.8 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 CRK19043.1 - 1.5e-11 44.1 0.0 2.1e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain XkdW PF09636.10 CRK19043.1 - 0.014 15.4 0.2 0.03 14.4 0.2 1.5 1 0 0 1 1 1 0 XkdW protein DNA_pol_B_2 PF03175.13 CRK19043.1 - 0.12 11.2 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral MMM1 PF10296.9 CRK19044.1 - 3.1e-13 49.5 2.1 1.8e-06 27.3 0.0 3.2 3 0 0 3 3 3 2 Maintenance of mitochondrial morphology protein 1 RloB PF13707.6 CRK19044.1 - 0.015 15.5 0.1 8.2 6.6 0.0 2.3 2 0 0 2 2 2 0 RloB-like protein PH_11 PF15413.6 CRK19044.1 - 0.083 13.3 0.1 41 4.7 0.0 3.3 4 0 0 4 4 4 0 Pleckstrin homology domain Mcp5_PH PF12814.7 CRK19046.1 - 1.7e-45 154.1 0.1 3.4e-45 153.1 0.1 1.5 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 CRK19046.1 - 2.9e-05 24.5 0.0 7.1e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 PH domain Inhibitor_I71 PF12628.7 CRK19046.1 - 0.038 13.8 0.9 8.9 6.1 0.1 2.7 2 0 0 2 2 2 0 Falstatin, cysteine peptidase inhibitor Autophagy_N PF03986.13 CRK19047.1 - 1e-46 158.3 0.0 1e-46 158.3 0.0 2.1 3 0 0 3 3 3 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 CRK19047.1 - 4.1e-15 56.1 0.0 9.1e-15 55.0 0.0 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain zf-CCCH PF00642.24 CRK19047.1 - 2.1e-07 30.7 3.7 2.1e-07 30.7 3.7 1.7 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CRK19047.1 - 4.3e-05 23.4 6.2 7.9e-05 22.6 6.2 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 CRK19047.1 - 0.00089 19.0 3.1 0.00089 19.0 3.1 2.1 2 0 0 2 2 2 1 CCCH-type zinc finger Autophagy_C PF10381.9 CRK19047.1 - 0.03 13.8 1.2 0.064 12.8 1.2 1.6 1 0 0 1 1 1 0 Autophagocytosis associated protein C-terminal zf-CCCH_2 PF14608.6 CRK19047.1 - 0.17 12.4 3.6 0.39 11.2 3.6 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger CCDC106 PF15794.5 CRK19050.1 - 2 8.1 5.6 2.7 7.6 0.1 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 Gly_transf_sug PF04488.15 CRK19051.1 - 2.1e-05 25.1 0.0 5.5e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 CRK19051.1 - 0.1 11.9 0.0 0.41 9.9 0.0 1.7 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain DUF2046 PF09755.9 CRK19053.1 - 0.033 13.4 1.8 0.067 12.4 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) Gly_transf_sug PF04488.15 CRK19055.1 - 2e-05 25.1 0.0 4.6e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif PBP PF01161.20 CRK19055.1 - 0.015 15.6 2.7 1.6 9.0 0.1 2.6 2 0 0 2 2 2 0 Phosphatidylethanolamine-binding protein DUF1435 PF07256.12 CRK19055.1 - 0.094 12.8 1.4 9.8 6.4 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1435) NrsF PF06532.11 CRK19055.1 - 0.14 11.8 4.4 13 5.4 0.0 3.4 3 0 0 3 3 3 0 Negative regulator of sigma F DUF2798 PF11391.8 CRK19055.1 - 10 6.3 8.7 17 5.5 0.6 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2798) PAF-AH_p_II PF03403.13 CRK19056.1 - 3.4e-19 68.6 0.0 1.3e-10 40.4 0.0 2.2 1 1 1 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_6 PF12697.7 CRK19056.1 - 2.4e-06 28.3 0.9 4.8e-06 27.3 0.9 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 CRK19056.1 - 0.00019 20.4 0.0 0.0004 19.4 0.0 1.5 1 1 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_5 PF12695.7 CRK19056.1 - 0.00094 19.0 0.0 0.18 11.5 0.0 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CRK19056.1 - 0.0042 16.8 0.0 0.053 13.2 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CRK19056.1 - 0.0045 16.3 0.0 0.22 10.8 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Lipase_3 PF01764.25 CRK19056.1 - 0.027 14.3 0.1 0.054 13.4 0.1 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF2974 PF11187.8 CRK19056.1 - 0.033 13.7 0.0 0.053 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_3 PF07859.13 CRK19056.1 - 0.067 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CRK19056.1 - 0.075 12.5 0.1 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DLH PF01738.18 CRK19056.1 - 0.14 11.7 0.0 0.32 10.5 0.0 1.5 1 1 0 1 1 1 0 Dienelactone hydrolase family Chlorophyllase PF07224.11 CRK19056.1 - 0.19 10.7 0.6 4.6 6.2 0.6 2.1 1 1 0 1 1 1 0 Chlorophyllase Cellulase PF00150.18 CRK19058.1 - 1.2e-18 67.5 1.1 1.6e-18 67.1 1.1 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 CRK19058.1 - 1e-12 47.7 13.2 2.5e-12 46.5 13.2 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Glyco_hydro_2_C PF02836.17 CRK19058.1 - 2.4e-05 23.6 0.1 0.00016 20.9 0.0 2.2 2 1 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.15 CRK19058.1 - 0.00033 20.1 0.4 0.0011 18.4 0.1 1.9 2 1 0 2 2 2 1 Beta-galactosidase Glyco_hydro_10 PF00331.20 CRK19058.1 - 0.0073 15.5 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Hfq PF17209.3 CRK19058.1 - 0.12 12.1 0.1 0.35 10.6 0.0 1.8 2 0 0 2 2 2 0 Hfq protein Toxin_7 PF05980.12 CRK19058.1 - 0.12 12.6 2.5 0.21 11.9 2.5 1.4 1 0 0 1 1 1 0 Toxin 7 Fungal_trans PF04082.18 CRK19060.1 - 2.2e-07 30.2 0.0 6.6e-07 28.6 0.0 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK19060.1 - 3.3e-06 27.1 10.6 3.3e-06 27.1 10.6 2.4 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_12 PF01670.16 CRK19061.1 - 6.3e-16 59.0 5.2 1.1e-15 58.3 5.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 CBM_1 PF00734.18 CRK19061.1 - 0.013 15.5 2.4 0.026 14.5 0.4 2.6 2 0 0 2 2 2 0 Fungal cellulose binding domain Polyoma_coat2 PF00761.20 CRK19061.1 - 0.06 13.1 0.3 0.12 12.1 0.3 1.4 1 0 0 1 1 1 0 Polyomavirus coat protein Peptidase_M14 PF00246.24 CRK19062.1 - 2.8e-69 234.1 0.0 3.8e-69 233.7 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase NMO PF03060.15 CRK19064.1 - 5e-31 108.3 13.3 1.8e-30 106.5 13.3 1.8 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 CRK19064.1 - 9.1e-09 34.8 6.2 2e-08 33.6 6.2 1.4 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 CRK19064.1 - 2.3e-06 26.9 7.7 3.5e-06 26.3 7.7 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 CRK19064.1 - 0.0011 18.1 3.5 0.0018 17.5 3.5 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase DUF4705 PF15788.5 CRK19065.1 - 0.15 12.3 1.6 0.34 11.2 1.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4705) APH PF01636.23 CRK19066.1 - 0.00034 20.6 0.1 0.00086 19.3 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF3858 PF12970.7 CRK19066.1 - 0.025 14.6 0.0 0.58 10.2 0.0 2.2 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3858) Vps5 PF09325.10 CRK19068.1 - 7.1e-11 42.1 0.0 9.1e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Vps5 C terminal like HATPase_c PF02518.26 CRK19068.1 - 2.2e-06 28.2 0.0 3.6e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Dcc1 PF09724.9 CRK19072.1 - 0.0026 17.1 1.1 0.003 16.9 1.1 1.1 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 FUSC PF04632.12 CRK19072.1 - 1.2 7.6 7.9 1.6 7.2 7.9 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family HemY_N PF07219.13 CRK19072.1 - 4.6 7.5 8.0 0.26 11.5 2.7 1.7 2 0 0 2 2 2 0 HemY protein N-terminus U-box PF04564.15 CRK19107.1 - 7.5e-05 22.8 0.0 0.00016 21.7 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-NOSIP PF15906.5 CRK19107.1 - 0.0037 17.4 0.0 0.0072 16.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein Ribosomal_L3 PF00297.22 CRK19118.1 - 7.2e-16 58.1 5.2 1.8e-13 50.3 1.6 2.1 1 1 1 2 2 2 2 Ribosomal protein L3 Cnd3 PF12719.7 CRK19121.1 - 2.7e-47 161.4 2.0 2.7e-47 161.4 2.0 1.7 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain DUF2423 PF10338.9 CRK19122.1 - 1e-19 70.5 3.8 1e-19 70.5 3.8 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) Phosphodiest PF01663.22 CRK19122.1 - 0.038 13.6 0.1 0.059 12.9 0.1 1.4 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase TonB_N PF16031.5 CRK19122.1 - 0.044 14.3 4.3 0.071 13.6 4.3 1.3 1 0 0 1 1 1 0 TonB polyproline region PINIT PF14324.6 CRK19123.1 - 1.1e-45 155.6 0.1 1.8e-45 154.9 0.1 1.4 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 CRK19123.1 - 4.7e-22 77.5 6.1 1e-21 76.4 6.1 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 CRK19123.1 - 5.8e-06 26.0 1.5 1.5e-05 24.7 1.5 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.27 CRK19123.1 - 0.00011 21.8 0.0 0.00029 20.5 0.0 1.7 1 0 0 1 1 1 1 SAP domain zf-Sec23_Sec24 PF04810.15 CRK19123.1 - 0.021 14.9 1.0 0.057 13.5 0.9 1.8 1 1 0 1 1 1 0 Sec23/Sec24 zinc finger FYVE_2 PF02318.16 CRK19123.1 - 0.055 13.7 0.9 0.11 12.7 0.9 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger Prok-RING_4 PF14447.6 CRK19123.1 - 0.46 10.4 3.1 1.1 9.1 3.1 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 CRK19123.1 - 1.5 9.1 4.9 3.5 7.8 4.9 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Ldh_1_C PF02866.18 CRK19124.1 - 8e-49 165.8 0.0 9.8e-49 165.5 0.0 1.1 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 CRK19124.1 - 1.7e-12 47.7 0.1 2.7e-12 47.0 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ribosomal_L28e PF01778.17 CRK19125.1 - 5.2e-31 107.8 2.3 5.2e-31 107.8 2.3 1.3 1 1 0 1 1 1 1 Ribosomal L28e protein family Ustilago_mating PF05722.12 CRK19125.1 - 0.044 13.3 4.9 0.062 12.8 4.9 1.3 1 0 0 1 1 1 0 Ustilago B locus mating-type protein DUF2015 PF09435.10 CRK19126.1 - 1.3e-46 157.0 0.0 1.5e-46 156.9 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) FixS PF03597.15 CRK19126.1 - 0.75 9.6 3.0 1.2 8.9 3.0 1.3 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type FA_hydroxylase PF04116.13 CRK19127.1 - 1.7e-23 83.4 15.2 1.7e-23 83.4 15.2 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily WD40 PF00400.32 CRK19128.1 - 4.7e-59 195.0 14.2 1.1e-08 35.6 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK19128.1 - 2.2e-14 53.5 0.0 0.00045 20.5 0.0 5.2 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Tup_N PF08581.10 CRK19128.1 - 9.3e-14 51.5 12.0 9.3e-14 51.5 12.0 1.7 2 0 0 2 2 1 1 Tup N-terminal Ge1_WD40 PF16529.5 CRK19128.1 - 1.1e-06 27.9 0.2 0.48 9.3 0.0 5.1 2 2 3 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 CRK19128.1 - 3.2e-05 23.4 0.0 0.5 9.6 0.0 4.5 4 1 1 5 5 5 2 WD40-like domain Nup160 PF11715.8 CRK19128.1 - 0.0065 15.2 0.2 2.4 6.7 0.0 3.5 1 1 2 4 4 4 1 Nucleoporin Nup120/160 DUF3037 PF11236.8 CRK19128.1 - 0.013 15.9 0.8 0.026 14.9 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3037) PD40 PF07676.12 CRK19128.1 - 0.023 14.6 0.0 11 6.0 0.0 4.1 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 CRK19128.1 - 0.05 12.1 0.4 0.43 9.0 0.2 2.2 1 1 1 2 2 2 0 Cytochrome D1 heme domain Nucleoporin_N PF08801.11 CRK19128.1 - 0.071 11.8 0.1 2.6 6.7 0.1 3.1 2 1 1 3 3 3 0 Nup133 N terminal like Nbas_N PF15492.6 CRK19128.1 - 0.15 11.4 0.1 24 4.1 0.0 3.0 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal SOG2 PF10428.9 CRK19128.1 - 4.6 6.3 8.4 6.1 5.9 8.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Aa_trans PF01490.18 CRK19130.1 - 3.4e-62 210.5 30.3 4.2e-62 210.2 30.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CDC45 PF02724.14 CRK19130.1 - 2.1 6.6 3.7 3.2 5.9 3.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Pkinase PF00069.25 CRK19131.1 - 1.8e-54 184.9 0.0 2.6e-54 184.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK19131.1 - 8.1e-31 107.2 0.0 1.2e-30 106.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CRK19131.1 - 2.9e-11 43.2 0.0 6.6e-09 35.5 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 CRK19131.1 - 0.0057 16.0 0.1 0.022 14.1 0.0 1.9 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family ABC1 PF03109.16 CRK19131.1 - 0.037 14.2 0.0 0.078 13.2 0.0 1.4 1 0 0 1 1 1 0 ABC1 family PAC1 PF16094.5 CRK19131.1 - 0.26 10.4 2.3 8.2 5.5 1.0 2.1 2 0 0 2 2 2 0 Proteasome assembly chaperone 4 Hydrolase PF00702.26 CRK19132.1 - 0.022 15.1 0.0 0.035 14.4 0.0 1.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CRK19132.1 - 0.24 11.4 0.0 0.35 10.9 0.0 1.2 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Ribosomal_L23eN PF03939.13 CRK19134.1 - 5.8e-23 80.8 8.8 5.8e-23 80.8 8.8 2.5 2 1 1 3 3 3 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 CRK19134.1 - 1.3e-15 57.5 0.7 1.3e-15 57.5 0.7 1.7 2 0 0 2 2 2 1 Ribosomal protein L23 zf-Tim10_DDP PF02953.15 CRK19136.1 - 3.3e-22 77.9 1.1 4.1e-22 77.6 1.1 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger CorA PF01544.18 CRK19138.1 - 1.1e-34 120.1 0.0 1.7e-34 119.5 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein zf-rbx1 PF12678.7 CRK19138.1 - 8.8e-20 70.7 12.3 1.8e-19 69.7 12.3 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CRK19138.1 - 2.2e-16 59.7 6.0 4.4e-16 58.7 6.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 CRK19138.1 - 0.015 15.7 12.6 0.14 12.6 12.6 2.3 1 1 0 1 1 1 0 Ring finger domain ALS2CR11 PF15729.5 CRK19138.1 - 0.12 11.6 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 candidate 11 zf-C3HC4 PF00097.25 CRK19138.1 - 0.42 10.5 9.6 2.1 8.3 9.6 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 CRK19138.1 - 2.7 8.3 8.0 7.6 6.8 8.0 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_11 PF17123.5 CRK19138.1 - 5.9 6.7 14.2 0.027 14.2 2.3 2.4 2 0 0 2 2 2 0 RING-like zinc finger SPC12 PF06645.13 CRK19139.1 - 1.8e-32 111.2 0.2 2.2e-32 111.0 0.2 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF3285 PF11688.8 CRK19139.1 - 0.12 12.3 1.5 0.28 11.2 1.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3285) Tyr-DNA_phospho PF06087.12 CRK19140.1 - 3.1e-39 135.1 0.0 3.8e-39 134.8 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase UIM PF02809.20 CRK19140.1 - 6.4 6.9 6.4 0.57 10.2 1.1 2.1 2 0 0 2 2 2 0 Ubiquitin interaction motif SPC12 PF06645.13 CRK19141.1 - 1.9e-31 107.9 0.2 2.3e-31 107.7 0.2 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) zf-rbx1 PF12678.7 CRK19142.1 - 3.3e-25 88.1 13.1 4.7e-25 87.6 13.1 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CRK19142.1 - 4.3e-17 62.0 10.0 5.7e-17 61.5 10.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 CRK19142.1 - 2.8e-06 27.6 14.6 9.7e-05 22.6 14.6 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CRK19142.1 - 0.0019 18.0 12.0 0.032 14.1 12.0 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CRK19142.1 - 0.0032 17.3 14.7 0.22 11.4 14.7 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CRK19142.1 - 0.18 11.7 10.6 0.52 10.2 4.4 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CRK19142.1 - 0.5 10.2 16.3 41 4.0 16.3 2.4 1 1 0 1 1 1 0 RING-like zinc finger zf-RING_UBOX PF13445.6 CRK19142.1 - 0.59 10.2 7.9 2.1 8.4 7.9 2.0 1 1 0 1 1 1 0 RING-type zinc-finger FANCL_C PF11793.8 CRK19142.1 - 0.6 10.3 9.3 3.2 8.0 9.5 2.0 1 1 1 2 2 2 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 CRK19142.1 - 0.73 9.5 14.9 0.14 11.8 4.7 2.3 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type Tyr-DNA_phospho PF06087.12 CRK19143.1 - 4.4e-64 216.9 0.0 1.4e-38 133.0 0.0 2.1 1 1 1 2 2 2 2 Tyrosyl-DNA phosphodiesterase PNRC PF15365.6 CRK19143.1 - 6.4e-08 32.2 7.3 6.4e-08 32.2 7.3 2.8 2 0 0 2 2 2 1 Proline-rich nuclear receptor coactivator motif PLDc_2 PF13091.6 CRK19143.1 - 0.0012 18.8 0.0 0.0074 16.2 0.0 2.0 2 0 0 2 2 2 1 PLD-like domain Gti1_Pac2 PF09729.9 CRK19144.1 - 1.6e-60 204.3 0.0 2.9e-60 203.5 0.0 1.4 1 0 0 1 1 1 1 Gti1/Pac2 family CDP-OH_P_transf PF01066.21 CRK19144.1 - 1.4e-14 54.6 1.1 1.4e-14 54.6 1.1 2.2 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Sec1 PF00995.23 CRK19145.1 - 1.9e-134 450.0 0.2 2.3e-134 449.7 0.2 1.1 1 0 0 1 1 1 1 Sec1 family GIDA PF01134.22 CRK19145.1 - 3.4e-116 388.6 0.1 2.7e-58 197.9 0.1 2.3 1 1 1 2 2 2 2 Glucose inhibited division protein A GIDA_assoc PF13932.6 CRK19145.1 - 8.7e-68 228.6 0.4 2.4e-67 227.2 0.0 1.9 2 0 0 2 2 2 1 GidA associated domain FAD_oxidored PF12831.7 CRK19145.1 - 1.4e-06 28.0 0.2 2.2e-06 27.3 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CRK19145.1 - 4.8e-06 26.0 0.2 1.6e-05 24.3 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CRK19145.1 - 0.00063 18.9 2.5 0.00063 18.9 2.5 1.9 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 CRK19145.1 - 0.00094 18.5 0.8 0.0023 17.2 0.8 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 CRK19145.1 - 0.033 14.6 0.0 0.11 12.9 0.0 2.0 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox PF00070.27 CRK19145.1 - 0.15 12.7 0.4 0.66 10.6 0.4 2.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CRK19145.1 - 0.16 10.6 1.9 0.53 8.9 0.9 2.3 2 0 0 2 2 2 0 HI0933-like protein MMM1 PF10296.9 CRK19146.1 - 3.5e-136 453.6 0.0 1.2e-134 448.6 0.0 2.1 1 1 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 MBOAT PF03062.19 CRK19147.1 - 4.1e-106 355.3 4.1 1e-53 183.0 0.6 2.7 2 0 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family CPBP PF02517.16 CRK19147.1 - 1.6e-15 57.2 7.2 1.6e-15 57.2 7.2 6.1 5 2 0 5 5 5 1 CPBP intramembrane metalloprotease DUF1925 PF09094.11 CRK19147.1 - 0.13 12.5 0.4 30 5.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1925) DsbC_N PF10411.9 CRK19147.1 - 0.18 11.3 0.5 23 4.5 0.1 2.4 2 0 0 2 2 2 0 Disulfide bond isomerase protein N-terminus YtpI PF14007.6 CRK19147.1 - 3.6 7.8 9.3 15 5.8 0.3 3.7 4 0 0 4 4 4 0 YtpI-like protein Synaptobrevin PF00957.21 CRK19148.1 - 9.3 6.1 6.4 5.3 6.9 1.7 2.3 2 0 0 2 2 2 0 Synaptobrevin DUF4508 PF14969.6 CRK19149.1 - 1e-05 25.7 1.6 0.16 12.3 0.1 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4508) EthD PF07110.11 CRK19149.1 - 0.00066 20.8 0.6 1.7 9.8 0.1 2.7 3 0 0 3 3 3 2 EthD domain DUF1765 PF08578.10 CRK19149.1 - 0.0074 16.8 0.4 5.5 7.5 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1765) Staufen_C PF16482.5 CRK19149.1 - 0.0075 16.4 0.6 3.4 7.8 0.1 2.5 2 0 0 2 2 2 2 Staufen C-terminal domain Tad PF13400.6 CRK19149.1 - 0.011 16.0 0.2 6.9 7.1 0.0 2.6 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like ECH_2 PF16113.5 CRK19149.1 - 0.044 13.3 2.2 2.4 7.6 0.2 2.1 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase Phage_TAC_5 PF08890.11 CRK19149.1 - 0.087 12.8 0.4 16 5.5 0.0 2.2 2 0 0 2 2 2 0 Phage XkdN-like tail assembly chaperone protein, TAC MerR-DNA-bind PF09278.11 CRK19149.1 - 0.095 13.3 7.0 4.2 8.0 0.6 2.9 2 0 0 2 2 2 0 MerR, DNA binding Enkurin PF13864.6 CRK19149.1 - 0.11 12.9 0.3 24 5.4 0.0 2.3 2 0 0 2 2 2 0 Calmodulin-binding Fmp27_SW PF10305.9 CRK19149.1 - 0.35 11.6 2.2 27 5.5 0.2 2.4 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain LuxT_C PF18285.1 CRK19149.1 - 0.82 10.2 3.1 39 4.9 0.2 2.8 2 0 0 2 2 2 0 Tetracycline repressor LuxT C-terminal domain GerPC PF10737.9 CRK19149.1 - 1.3 9.1 10.8 9.4 6.3 0.3 3.8 2 2 2 4 4 4 0 Spore germination protein GerPC FCD PF07729.12 CRK19149.1 - 1.7 9.1 7.1 9.3 6.7 0.7 2.2 2 0 0 2 2 2 0 FCD domain Endosulfine PF04667.17 CRK19154.1 - 3.2e-26 91.3 0.0 4.1e-26 90.9 0.0 1.2 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Inhibitor_I78 PF11720.8 CRK19158.1 - 0.055 13.5 0.0 0.055 13.5 0.0 1.0 1 0 0 1 1 1 0 Peptidase inhibitor I78 family FGGY_N PF00370.21 CRK19161.1 - 6.8e-05 22.6 0.1 0.00048 19.8 0.1 1.9 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain TCTP PF00838.17 CRK19170.1 - 1.1e-21 77.9 0.3 1.6e-21 77.4 0.3 1.2 1 0 0 1 1 1 1 Translationally controlled tumour protein DUF2937 PF11157.8 CRK19170.1 - 0.18 11.5 1.3 0.35 10.6 1.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2937) Ribosomal_L18A PF01775.17 CRK19185.1 - 1.6e-40 138.0 0.7 2.2e-40 137.5 0.7 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Myosin_head PF00063.21 CRK19199.1 - 6.2e-42 143.7 0.0 7.4e-42 143.4 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) R3H PF01424.22 CRK19201.1 - 2.7e-11 43.3 0.3 5.3e-11 42.3 0.3 1.5 1 0 0 1 1 1 1 R3H domain RRM_1 PF00076.22 CRK19201.1 - 4.6e-05 23.1 0.0 0.00016 21.4 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_2 PF04059.12 CRK19201.1 - 0.13 12.4 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif 2 RdRP PF05183.12 CRK19202.1 - 2e-185 617.9 0.0 2.6e-185 617.5 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase PHO4 PF01384.20 CRK19203.1 - 7.6e-112 373.7 17.2 8.7e-112 373.5 17.2 1.0 1 0 0 1 1 1 1 Phosphate transporter family Mre11_DNA_bind PF04152.14 CRK19204.1 - 1.3e-54 185.0 0.6 1.3e-54 185.0 0.6 1.9 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 CRK19204.1 - 2.5e-17 64.1 2.0 4.8e-17 63.1 2.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CRK19204.1 - 0.00013 22.2 0.0 0.00097 19.4 0.0 2.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF2884 PF11101.8 CRK19204.1 - 0.035 13.6 0.7 0.075 12.5 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) GrpB PF04229.14 CRK19206.1 - 2.2e-41 141.7 0.0 2.5e-41 141.5 0.0 1.0 1 0 0 1 1 1 1 GrpB protein Kinesin PF00225.23 CRK19207.1 - 2.9e-51 174.4 0.0 5e-51 173.6 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain HATPase_c PF02518.26 CRK19207.1 - 6.2e-21 75.0 0.1 1.4e-20 73.8 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 CRK19207.1 - 2.8e-18 66.1 0.0 2.1e-17 63.3 0.0 2.3 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 CRK19207.1 - 6.2e-11 42.2 0.8 1.6e-10 40.9 0.1 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Microtub_bd PF16796.5 CRK19207.1 - 5.2e-07 29.7 0.0 1e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding ThiG PF05690.14 CRK19207.1 - 0.049 12.9 0.6 0.15 11.3 0.0 2.0 3 0 0 3 3 3 0 Thiazole biosynthesis protein ThiG P21-Arc PF04062.14 CRK19209.1 - 3.7e-70 235.5 0.0 5e-70 235.1 0.0 1.2 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit ABC_tran PF00005.27 CRK19209.1 - 2.7e-30 105.6 0.0 5.3e-30 104.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CRK19209.1 - 5.6e-07 29.2 0.0 9.1e-05 22.0 0.0 2.1 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 CRK19209.1 - 0.0088 16.1 0.0 0.017 15.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_21 PF13304.6 CRK19209.1 - 0.019 14.8 0.2 0.82 9.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 CRK19209.1 - 0.059 13.7 0.1 0.13 12.6 0.1 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 CRK19209.1 - 0.089 12.5 0.0 0.2 11.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain DUF87 PF01935.17 CRK19209.1 - 0.11 12.5 0.1 0.21 11.6 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_22 PF13401.6 CRK19209.1 - 0.16 12.3 0.1 0.7 10.2 0.1 2.1 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 CRK19209.1 - 0.25 11.1 0.3 0.85 9.3 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein Gcd10p PF04189.13 CRK19210.1 - 8.4e-115 383.0 0.0 1e-114 382.7 0.0 1.0 1 0 0 1 1 1 1 Gcd10p family Pox_I3 PF04661.12 CRK19210.1 - 0.0057 15.8 0.0 0.01 15.0 0.0 1.3 1 0 0 1 1 1 1 Poxvirus I3 ssDNA-binding protein HIRA_B PF09453.10 CRK19211.1 - 0.0052 16.6 0.6 0.012 15.4 0.6 1.7 1 0 0 1 1 1 1 HIRA B motif ABC_membrane PF00664.23 CRK19212.1 - 9.8e-32 110.7 12.9 9.7e-25 87.7 8.6 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CRK19212.1 - 3.8e-19 69.6 0.0 1.1e-18 68.0 0.0 1.8 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 CRK19212.1 - 3.3e-07 30.0 0.8 0.063 12.7 0.1 3.3 2 1 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CRK19212.1 - 0.011 16.3 0.0 0.028 14.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CRK19212.1 - 0.051 13.3 0.1 0.15 11.9 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SSE PF00437.20 CRK19212.1 - 0.093 11.8 0.0 0.2 10.7 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein RsgA_GTPase PF03193.16 CRK19212.1 - 0.16 11.8 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase Dynamin_N PF00350.23 CRK19212.1 - 0.17 11.9 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 Dynamin family WD40 PF00400.32 CRK19213.1 - 1.1e-17 64.1 17.8 7.5e-05 23.4 0.1 7.2 8 0 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK19213.1 - 3.2e-16 59.4 0.0 9.9e-06 25.8 0.0 5.5 4 2 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CRK19213.1 - 9e-06 25.7 0.3 0.033 14.1 0.0 3.7 3 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 CRK19213.1 - 0.0027 17.6 7.0 1.7 8.7 0.3 4.5 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 CRK19213.1 - 0.0073 15.3 0.1 18 4.1 0.0 3.8 2 1 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein TFIIIC_delta PF12657.7 CRK19213.1 - 0.037 13.9 1.2 24 4.8 0.2 3.3 2 1 0 2 2 2 0 Transcription factor IIIC subunit delta N-term IKI3 PF04762.12 CRK19213.1 - 0.25 9.3 0.1 0.89 7.5 0.1 1.8 1 1 0 1 1 1 0 IKI3 family TMEM171 PF15471.6 CRK19213.1 - 0.33 9.9 9.6 0.59 9.1 5.3 2.3 2 0 0 2 2 2 0 Transmembrane protein family 171 LigD_N PF13298.6 CRK19214.1 - 7.8e-35 119.3 0.1 1.3e-34 118.6 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase Ligase (LigD) DUF3246 PF11596.8 CRK19214.1 - 2.2 7.7 7.7 0.59 9.5 4.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) eIF-3c_N PF05470.12 CRK19214.1 - 4.5 5.5 6.1 23 3.1 3.7 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF3395 PF11875.8 CRK19215.1 - 1.9e-24 86.3 0.0 3.3e-24 85.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 CRK19215.1 - 1.6e-05 25.0 0.0 3.2e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain BLACT_WH PF17778.1 CRK19215.1 - 0.027 14.5 0.1 0.068 13.2 0.1 1.7 1 0 0 1 1 1 0 Beta-lactamase associated winged helix domain Fungal_trans PF04082.18 CRK19216.1 - 2.4e-09 36.6 0.3 4.6e-09 35.7 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain MARVEL PF01284.23 CRK19217.1 - 3.6e-06 27.1 23.8 7.1e-06 26.1 23.8 1.5 1 1 0 1 1 1 1 Membrane-associating domain DUF2157 PF09925.9 CRK19217.1 - 0.071 12.9 7.7 0.12 12.2 6.7 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) YpmT PF17431.2 CRK19217.1 - 0.24 11.5 1.6 0.66 10.0 1.6 1.8 1 0 0 1 1 1 0 Uncharacterized YmpT-like Arteri_Gl PF00951.18 CRK19217.1 - 3.3 7.5 11.0 1.8 8.4 7.8 2.1 1 1 1 2 2 2 0 Arterivirus GL envelope glycoprotein GIT_SHD PF08518.11 CRK19218.1 - 1.2e-21 76.0 5.5 5.4e-10 38.7 0.1 2.8 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT Spc7 PF08317.11 CRK19218.1 - 0.14 11.0 31.1 0.02 13.8 15.4 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein THP2 PF09432.10 CRK19218.1 - 0.4 10.7 6.4 0.19 11.8 2.8 2.3 1 1 0 1 1 1 0 Tho complex subunit THP2 PSII_Pbs27 PF13326.6 CRK19218.1 - 0.41 11.0 6.7 0.28 11.5 0.3 2.9 2 1 0 2 2 2 0 Photosystem II Pbs27 CLZ PF16526.5 CRK19218.1 - 2.2 8.7 15.4 0.31 11.4 0.4 4.6 3 1 0 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CSN5_C PF18323.1 CRK19218.1 - 2.2 9.2 10.1 7.1 7.6 1.0 3.2 2 0 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain UPF0242 PF06785.11 CRK19218.1 - 4.8 7.2 36.0 2.2 8.3 14.0 2.7 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus SHE3 PF17078.5 CRK19218.1 - 9.3 5.9 24.0 1.9 8.1 17.3 2.6 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 RTA1 PF04479.13 CRK19219.1 - 1.2e-65 221.0 12.3 1.2e-65 221.0 12.3 1.7 2 0 0 2 2 2 1 RTA1 like protein Kei1 PF08552.11 CRK19219.1 - 0.0088 15.9 0.1 0.022 14.6 0.1 1.6 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 DUF962 PF06127.11 CRK19219.1 - 0.12 12.5 1.8 7.4 6.7 2.1 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF962) HisKA_7TM PF16927.5 CRK19219.1 - 1.5 8.8 23.1 73 3.3 24.9 2.1 1 1 0 1 1 1 0 N-terminal 7TM region of histidine kinase Ssu72 PF04722.13 CRK19220.1 - 2.4e-84 281.7 0.0 2.8e-84 281.5 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein DsrH PF04077.12 CRK19220.1 - 0.16 12.1 0.0 8.7 6.6 0.0 2.3 2 0 0 2 2 2 0 DsrH like protein FAD_binding_6 PF00970.24 CRK19221.1 - 7.8e-24 83.9 0.0 1.1e-23 83.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 CRK19221.1 - 7.5e-14 52.3 0.0 1.1e-06 29.3 0.0 2.5 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 CRK19221.1 - 8.9e-07 29.1 0.0 0.0049 17.0 0.0 2.4 2 0 0 2 2 2 2 Ferric reductase NAD binding domain TFR_dimer PF04253.15 CRK19222.1 - 4.1e-21 75.3 0.0 8.1e-21 74.4 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 CRK19222.1 - 4.6e-14 52.6 0.3 1.3e-11 44.5 0.0 2.3 1 1 0 2 2 2 2 Peptidase family M28 PA PF02225.22 CRK19222.1 - 4e-08 33.2 0.2 4.4e-07 29.8 0.2 2.5 1 1 0 1 1 1 1 PA domain Nicastrin PF05450.15 CRK19222.1 - 0.043 13.3 0.0 0.075 12.5 0.0 1.3 1 0 0 1 1 1 0 Nicastrin Peptidase_M20 PF01546.28 CRK19222.1 - 0.13 12.0 0.1 0.66 9.6 0.2 1.6 1 1 0 1 1 1 0 Peptidase family M20/M25/M40 MFS_1 PF07690.16 CRK19223.1 - 1.3e-27 96.7 43.2 6.2e-23 81.3 14.3 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily IMPDH PF00478.25 CRK19224.1 - 3.5e-126 420.9 2.0 4.1e-126 420.6 2.0 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 CRK19224.1 - 7.6e-14 51.9 0.0 1.9e-05 25.0 0.0 2.5 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.18 CRK19224.1 - 4.9e-08 32.4 1.0 1.9e-06 27.1 0.7 2.3 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.15 CRK19224.1 - 2e-07 30.7 1.8 0.003 17.0 1.4 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.21 CRK19224.1 - 0.0011 18.5 2.1 0.03 13.8 0.2 2.2 1 1 1 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.14 CRK19224.1 - 0.048 13.0 0.3 0.11 11.8 0.3 1.5 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG RasGAP PF00616.19 CRK19225.1 - 4.6e-51 173.5 0.0 1.2e-50 172.1 0.0 1.8 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 CRK19225.1 - 3.2e-48 163.3 1.7 3.2e-48 163.3 1.7 2.2 2 0 0 2 2 2 1 RasGAP C-terminus IQ PF00612.27 CRK19225.1 - 6.6e-11 41.0 46.3 0.0019 17.8 0.0 12.7 14 0 0 14 14 14 5 IQ calmodulin-binding motif CH PF00307.31 CRK19225.1 - 7e-10 39.1 0.1 2.9e-09 37.1 0.0 2.1 2 0 0 2 2 2 1 Calponin homology (CH) domain DUF2207 PF09972.9 CRK19228.1 - 0.4 9.4 0.0 0.4 9.4 0.0 2.5 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) Vps8 PF12816.7 CRK19229.1 - 2.5e-73 245.8 0.0 4.4e-73 245.0 0.0 1.4 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 MBOAT PF03062.19 CRK19229.1 - 5.6e-47 160.8 13.3 5.6e-47 160.8 13.3 1.9 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Clathrin PF00637.20 CRK19229.1 - 0.00062 19.7 0.0 1.5 8.7 0.0 2.9 2 0 0 2 2 2 2 Region in Clathrin and VPS FAM196 PF15265.6 CRK19231.1 - 0.14 11.6 2.1 0.19 11.2 2.1 1.2 1 0 0 1 1 1 0 FAM196 family NPV_P10 PF05531.12 CRK19231.1 - 0.15 12.5 1.3 0.59 10.6 0.2 2.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein UVR PF02151.19 CRK19231.1 - 0.26 11.1 10.1 3.8 7.4 0.3 3.5 3 0 0 3 3 3 0 UvrB/uvrC motif DUF4407 PF14362.6 CRK19231.1 - 0.44 9.9 7.9 0.53 9.6 7.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 CRK19231.1 - 3.9 6.3 9.8 6.2 5.6 9.8 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein Ald_Xan_dh_C2 PF02738.18 CRK19232.1 - 5.6e-33 114.2 0.1 6.7e-33 114.0 0.1 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Fungal_trans_2 PF11951.8 CRK19239.1 - 6.4e-28 97.6 0.0 7e-28 97.5 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_23 PF13489.6 CRK19249.1 - 0.00013 21.8 0.0 0.00017 21.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain HECT_2 PF09814.9 CRK19269.1 - 5.3e-100 334.9 0.0 5.9e-100 334.7 0.0 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Ribosomal_L32p PF01783.23 CRK19269.1 - 0.086 13.1 0.3 6.1 7.2 0.1 2.4 2 0 0 2 2 2 0 Ribosomal L32p protein family zinc_ribbon_10 PF10058.9 CRK19269.1 - 0.16 11.7 0.2 9.7 6.0 0.0 2.3 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein LSM PF01423.22 CRK19270.1 - 1.9e-16 59.5 0.0 2.6e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 LSM domain IU_nuc_hydro PF01156.19 CRK19271.1 - 4.7e-54 184.0 0.1 2.2e-40 139.1 0.0 2.6 2 1 0 2 2 2 2 Inosine-uridine preferring nucleoside hydrolase Transketolase_C PF02780.20 CRK19271.1 - 0.029 14.3 0.0 0.079 12.9 0.0 1.7 1 0 0 1 1 1 0 Transketolase, C-terminal domain PVL_ORF50 PF07768.11 CRK19273.1 - 0.15 12.4 0.4 0.15 12.4 0.4 2.6 2 1 1 3 3 3 0 PVL ORF-50-like family Rhomboid PF01694.22 CRK19275.1 - 1.7e-18 67.1 11.6 1.7e-18 67.1 11.6 2.0 2 0 0 2 2 2 1 Rhomboid family PVL_ORF50 PF07768.11 CRK19276.1 - 8.6 6.7 9.3 0.18 12.2 0.5 2.5 3 1 1 4 4 4 0 PVL ORF-50-like family Rhomboid PF01694.22 CRK19278.1 - 7.2e-18 65.0 14.2 7.2e-18 65.0 14.2 1.8 1 1 1 2 2 2 1 Rhomboid family GPHR_N PF12537.8 CRK19278.1 - 0.12 12.5 0.0 0.31 11.2 0.0 1.6 1 0 0 1 1 1 0 The Golgi pH Regulator (GPHR) Family N-terminal Spt20 PF12090.8 CRK19279.1 - 0.19 11.3 8.4 0.7 9.5 7.1 2.1 2 0 0 2 2 2 0 Spt20 family Metallophos PF00149.28 CRK19280.1 - 1.4e-09 38.8 0.2 2.3e-09 38.1 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CRK19280.1 - 0.0001 22.6 0.1 0.0015 18.8 0.1 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain F-box-like PF12937.7 CRK19282.1 - 0.0097 15.8 0.3 0.023 14.6 0.3 1.7 1 0 0 1 1 1 1 F-box-like RNB PF00773.19 CRK19283.1 - 2.1e-54 185.1 0.0 3e-54 184.5 0.0 1.3 1 0 0 1 1 1 1 RNB domain Sec10 PF07393.11 CRK19284.1 - 8.9e-220 731.8 5.7 8.9e-220 731.8 5.7 1.6 2 0 0 2 2 2 1 Exocyst complex component Sec10 H-kinase_dim PF02895.14 CRK19284.1 - 0.26 11.7 2.6 2.1 8.8 0.1 3.7 2 2 1 3 3 3 0 Signal transducing histidine kinase, homodimeric domain Prenyltransf PF01255.19 CRK19286.1 - 0.027 14.0 0.0 0.26 10.8 0.0 2.1 2 0 0 2 2 2 0 Putative undecaprenyl diphosphate synthase Rer1 PF03248.13 CRK19286.1 - 0.037 13.8 0.1 0.084 12.6 0.0 1.5 2 0 0 2 2 2 0 Rer1 family Sec10 PF07393.11 CRK19287.1 - 3.8e-09 35.6 0.0 1.9e-08 33.3 0.0 1.8 2 0 0 2 2 2 1 Exocyst complex component Sec10 H-kinase_dim PF02895.14 CRK19287.1 - 0.053 13.9 1.2 0.21 12.0 0.1 2.2 1 1 1 2 2 2 0 Signal transducing histidine kinase, homodimeric domain Baculo_PEP_C PF04513.12 CRK19287.1 - 0.062 13.3 0.7 0.098 12.7 0.7 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Phage_Mu_Gam PF07352.12 CRK19287.1 - 0.13 12.2 0.7 0.61 10.0 0.1 1.9 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein Prenyltransf PF01255.19 CRK19288.1 - 0.015 14.8 0.0 0.19 11.2 0.0 2.1 2 0 0 2 2 2 0 Putative undecaprenyl diphosphate synthase Rer1 PF03248.13 CRK19288.1 - 0.019 14.7 0.1 0.042 13.6 0.0 1.5 2 0 0 2 2 2 0 Rer1 family 2OG-FeII_Oxy_2 PF13532.6 CRK19289.1 - 2.2e-54 184.6 0.0 3.2e-26 92.7 0.0 2.4 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily FTO_NTD PF12933.7 CRK19289.1 - 0.0019 17.5 0.0 2.4 7.3 0.0 2.6 2 0 0 2 2 2 2 FTO catalytic domain 7TM_GPCR_Srbc PF10316.9 CRK19289.1 - 0.9 9.0 1.7 28 4.1 0.1 2.1 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srbc HIF-1 PF11413.8 CRK19289.1 - 2.2 7.7 4.0 28 4.2 0.3 2.4 2 0 0 2 2 2 0 Hypoxia-inducible factor-1 Met_10 PF02475.16 CRK19290.1 - 1.3e-70 237.2 0.0 1.7e-70 236.8 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein DUF1752 PF08550.10 CRK19291.1 - 2e-10 40.3 7.2 2e-10 40.3 7.2 2.2 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1752) PBP1_TM PF14812.6 CRK19291.1 - 1.6 9.1 6.1 4.6 7.7 3.2 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC37_C PF08564.10 CRK19293.1 - 0.027 14.6 0.1 0.031 14.4 0.1 1.1 1 0 0 1 1 1 0 Cdc37 C terminal domain Patatin PF01734.22 CRK19294.1 - 9.1e-25 88.0 0.0 2.3e-24 86.7 0.0 1.7 1 1 0 1 1 1 1 Patatin-like phospholipase DUF456 PF04306.13 CRK19295.1 - 0.015 15.6 8.3 0.015 15.6 8.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF456) DUF575 PF04746.12 CRK19295.1 - 0.12 12.6 0.1 0.21 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF575) PMT_4TMC PF16192.5 CRK19298.1 - 5.5e-14 52.2 0.3 7.1e-14 51.9 0.3 1.2 1 0 0 1 1 1 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 CRK19298.1 - 2.2e-07 30.9 0.1 8.5e-07 29.0 0.1 1.7 1 1 1 2 2 2 2 MIR domain Pkinase PF00069.25 CRK19300.1 - 0.0025 17.2 0.0 0.0029 17.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain DUF4971 PF16341.5 CRK19301.1 - 0.059 13.2 0.0 0.093 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4971) Peptidase_M16 PF00675.20 CRK19304.1 - 2.2e-42 144.5 0.0 3e-42 144.1 0.0 1.2 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CRK19304.1 - 2e-12 47.5 0.0 3.8e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain Disulph_isomer PF06491.11 CRK19304.1 - 0.1 12.7 0.1 0.24 11.5 0.1 1.5 1 0 0 1 1 1 0 Disulphide isomerase PRP3 PF08572.10 CRK19306.1 - 1.7e-38 132.6 7.3 2.5e-38 132.1 7.3 1.3 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) GET2 PF08690.10 CRK19306.1 - 0.0049 16.6 5.7 0.0052 16.5 5.7 1.0 1 0 0 1 1 1 1 GET complex subunit GET2 MalF_P2 PF14785.6 CRK19306.1 - 0.039 14.0 1.4 0.051 13.6 1.4 1.4 1 1 0 1 1 1 0 Maltose transport system permease protein MalF P2 domain DUF4519 PF15012.6 CRK19306.1 - 1.7 8.8 7.6 11 6.2 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) zf_CCCH_4 PF18345.1 CRK19339.1 - 1.7e-08 34.2 9.8 2.4e-06 27.4 0.6 3.0 2 1 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 CRK19339.1 - 3.4e-07 30.0 3.5 0.00051 19.9 0.4 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CRK19339.1 - 2.9e-05 23.8 12.0 0.00076 19.2 0.4 3.1 2 1 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 CRK19339.1 - 4.8e-05 23.7 5.0 0.063 13.8 0.9 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger HBS1_N PF08938.10 CRK19339.1 - 0.0017 18.6 0.8 0.041 14.2 0.0 2.3 2 0 0 2 2 2 1 HBS1 N-terminus zf-CCCH_3 PF15663.5 CRK19339.1 - 0.041 14.1 3.1 2.1 8.6 0.2 2.3 1 1 1 2 2 2 0 Zinc-finger containing family Torus PF16131.5 CRK19339.1 - 0.13 13.0 5.0 1.4 9.7 0.4 2.3 1 1 1 2 2 2 0 Torus domain UBA_4 PF14555.6 CRK19339.1 - 0.14 12.0 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 UBA-like domain Cupin_8 PF13621.6 CRK19343.1 - 8.1e-20 71.6 0.1 1.9e-18 67.1 0.1 2.1 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 CRK19343.1 - 1.4e-11 44.9 0.1 2.4e-11 44.0 0.1 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase F-box-like PF12937.7 CRK19343.1 - 0.00056 19.8 0.7 0.0011 18.8 0.7 1.5 1 0 0 1 1 1 1 F-box-like Cupin_4 PF08007.12 CRK19343.1 - 0.051 13.0 0.0 0.091 12.2 0.0 1.4 1 0 0 1 1 1 0 Cupin superfamily protein F-box PF00646.33 CRK19343.1 - 0.061 13.2 0.1 0.17 11.8 0.1 1.8 1 0 0 1 1 1 0 F-box domain Cupin_2 PF07883.11 CRK19343.1 - 0.073 12.8 0.0 1.4 8.7 0.0 2.6 3 0 0 3 3 3 0 Cupin domain Glyco_transf_90 PF05686.12 CRK19343.1 - 0.14 11.0 0.1 0.25 10.2 0.1 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 90 DEAD PF00270.29 CRK19345.1 - 5.4e-09 36.1 0.1 6.7e-09 35.8 0.1 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase dCMP_cyt_deam_1 PF00383.23 CRK19347.1 - 8.6e-15 54.5 0.1 1.1e-14 54.1 0.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 CRK19347.1 - 1e-06 29.0 3.0 4.9e-06 26.8 0.3 2.1 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 CRK19347.1 - 0.12 11.9 0.5 0.64 9.6 0.5 1.9 1 1 0 1 1 1 0 A distinct subfamily of CDD/CDA-like deaminases Asp PF00026.23 CRK19349.1 - 1.9e-33 116.2 0.0 3e-33 115.6 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease adh_short_C2 PF13561.6 CRK19349.1 - 3.4e-30 105.3 0.0 1e-29 103.8 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRK19349.1 - 1.7e-24 86.4 0.0 2.7e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CRK19349.1 - 2.5e-07 30.8 0.0 6.5e-07 29.4 0.0 1.6 2 0 0 2 2 2 1 KR domain TAXi_N PF14543.6 CRK19349.1 - 6.2e-07 29.8 0.0 2.6e-05 24.5 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 CRK19349.1 - 0.036 14.7 0.4 15 6.3 0.0 3.2 3 1 0 3 3 3 0 Aspartyl protease DnaJ_C PF01556.18 CRK19351.1 - 6.1e-37 127.0 0.1 8.1e-37 126.6 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CRK19351.1 - 8.6e-27 93.1 2.8 1.5e-26 92.3 2.8 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CRK19351.1 - 2.5e-07 30.9 8.5 5.7e-07 29.8 8.5 1.6 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 CRK19351.1 - 1.1 9.3 4.5 0.67 10.0 1.8 2.1 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein CPSF_A PF03178.15 CRK19354.1 - 0.1 11.9 0.0 4.6 6.5 0.0 2.4 2 1 0 2 2 2 0 CPSF A subunit region Ribosomal_L10 PF00466.20 CRK19355.1 - 1.8e-22 79.3 0.0 4.4e-22 78.1 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L10 RL10P_insert PF17777.1 CRK19355.1 - 3.2e-22 78.3 0.0 6.3e-22 77.4 0.0 1.5 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 CRK19355.1 - 1.1e-18 67.5 4.5 1.1e-18 67.5 4.5 2.1 2 0 0 2 2 2 1 60s Acidic ribosomal protein WRNPLPNID PF15017.6 CRK19355.1 - 0.029 15.3 1.0 0.059 14.3 1.0 1.5 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box VirE_N PF08800.10 CRK19355.1 - 0.037 14.1 0.0 0.067 13.3 0.0 1.3 1 0 0 1 1 1 0 VirE N-terminal domain Glyco_hydro_38N PF01074.22 CRK19357.1 - 5.2e-87 291.9 3.3 8.7e-87 291.1 3.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 CRK19357.1 - 1e-54 185.8 0.6 2.3e-53 181.5 0.0 2.6 3 0 0 3 3 3 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 CRK19357.1 - 1.5e-26 92.4 0.0 3.6e-26 91.1 0.0 1.7 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 CRK19357.1 - 7.5e-10 38.8 0.0 6.3e-09 35.8 0.0 2.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Pkinase PF00069.25 CRK19359.1 - 1.2e-16 60.9 0.0 7.4e-12 45.2 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Abhydrolase_1 PF00561.20 CRK19359.1 - 1.3e-06 28.2 0.0 7.8e-06 25.7 0.1 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CRK19359.1 - 0.00044 20.9 0.9 0.00044 20.9 0.9 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Pkinase_Tyr PF07714.17 CRK19359.1 - 0.00052 19.4 0.0 0.077 12.3 0.0 2.5 2 1 1 3 3 3 2 Protein tyrosine kinase Hydrolase_4 PF12146.8 CRK19359.1 - 0.037 13.3 0.0 0.11 11.7 0.1 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 CRK19359.1 - 0.14 11.6 1.8 0.25 10.8 0.0 2.2 3 0 0 3 3 3 0 Prolyl oligopeptidase family CAP_GLY PF01302.25 CRK19361.1 - 8.5e-17 60.9 0.4 3.6e-16 58.9 0.3 2.1 2 0 0 2 2 2 1 CAP-Gly domain CLIP1_ZNF PF16641.5 CRK19361.1 - 8e-05 22.4 15.4 0.00046 20.0 1.3 3.1 3 0 0 3 3 3 2 CLIP1 zinc knuckle AAA_13 PF13166.6 CRK19361.1 - 0.0011 17.7 8.8 0.0011 17.7 8.8 1.9 1 1 1 2 2 2 1 AAA domain NPV_P10 PF05531.12 CRK19361.1 - 0.033 14.7 2.5 2.4 8.7 0.3 3.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Med4 PF10018.9 CRK19361.1 - 0.073 12.7 12.9 0.42 10.3 1.0 2.9 2 1 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Sec2p PF06428.11 CRK19361.1 - 0.15 12.0 17.8 0.15 12.1 0.6 4.2 4 0 0 4 4 4 0 GDP/GTP exchange factor Sec2p DUF3349 PF11829.8 CRK19361.1 - 0.16 12.8 1.5 0.61 10.9 1.5 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3349) sCache_like PF16736.5 CRK19361.1 - 0.4 10.8 3.6 14 5.8 0.1 2.4 2 0 0 2 2 2 0 Single Cache-like DUF812 PF05667.11 CRK19361.1 - 0.64 8.8 27.9 1 8.2 9.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF812) DUF1664 PF07889.12 CRK19361.1 - 0.75 9.8 12.3 0.43 10.6 1.9 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Glutaredoxin2_C PF04399.13 CRK19361.1 - 0.85 9.5 6.2 5.3 6.9 0.2 3.0 3 0 0 3 3 3 0 Glutaredoxin 2, C terminal domain DUF948 PF06103.11 CRK19361.1 - 1.3 9.3 3.6 1.5 9.1 0.7 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) BLOC1_2 PF10046.9 CRK19361.1 - 1.4 9.2 17.8 0.35 11.2 2.5 4.0 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 zf_PR_Knuckle PF18445.1 CRK19361.1 - 4.7 7.1 5.3 14 5.6 0.4 2.5 2 0 0 2 2 2 0 PR zinc knuckle motif EzrA PF06160.12 CRK19361.1 - 5.6 5.0 16.0 0.93 7.6 10.2 2.3 2 1 0 2 2 2 0 Septation ring formation regulator, EzrA DUF745 PF05335.13 CRK19361.1 - 7.5 6.2 18.1 0.36 10.5 2.4 3.4 2 1 0 3 3 3 0 Protein of unknown function (DUF745) Nop14 PF04147.12 CRK19365.1 - 5.1e-231 769.5 31.8 1.5e-229 764.6 26.2 4.3 3 1 1 4 4 4 2 Nop14-like family RecQ_Zn_bind PF16124.5 CRK19365.1 - 1.9e-18 66.9 4.7 9e-18 64.8 4.7 2.3 1 0 0 1 1 1 1 RecQ zinc-binding Helicase_C PF00271.31 CRK19365.1 - 7.2e-16 58.5 0.0 2.4e-15 56.8 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CRK19365.1 - 7.6e-05 22.5 0.0 0.0053 16.5 0.0 2.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase HRDC PF00570.23 CRK19365.1 - 0.00018 21.4 0.1 0.00018 21.4 0.1 3.0 3 0 0 3 3 3 1 HRDC domain RQC PF09382.10 CRK19365.1 - 0.0064 16.3 0.4 0.025 14.4 0.2 2.0 2 0 0 2 2 2 1 RQC domain GPI-anchored PF10342.9 CRK19369.1 - 8.2e-18 65.0 0.1 8.2e-18 65.0 0.1 2.5 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Hamartin PF04388.12 CRK19369.1 - 5.6 5.5 7.8 7.1 5.2 7.8 1.0 1 0 0 1 1 1 0 Hamartin protein ABM PF03992.16 CRK19371.1 - 0.067 13.3 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase KH_1 PF00013.29 CRK19373.1 - 8.9e-42 140.8 6.9 1.5e-17 63.1 0.6 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 CRK19373.1 - 8.9e-13 47.9 3.6 0.0037 17.1 0.3 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 CRK19373.1 - 5.9e-06 26.1 3.8 0.36 10.7 0.1 3.9 4 0 0 4 4 4 2 KH domain MOEP19 PF16005.5 CRK19373.1 - 0.00015 21.7 0.0 0.044 13.8 0.0 2.8 3 0 0 3 3 3 1 KH-like RNA-binding domain KH_5 PF13184.6 CRK19373.1 - 0.0023 18.0 9.2 0.38 10.9 0.4 3.4 3 0 0 3 3 3 2 NusA-like KH domain CENP-K PF11802.8 CRK19375.1 - 3.2e-12 46.6 5.8 0.00018 21.2 0.0 2.3 2 1 0 2 2 2 2 Centromere-associated protein K TcdB_N PF12918.7 CRK19375.1 - 0.0054 17.0 8.1 0.12 12.7 1.9 3.4 2 1 1 3 3 3 1 TcdB toxin N-terminal helical domain DUF445 PF04286.12 CRK19375.1 - 0.006 16.4 6.2 0.026 14.4 5.4 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF445) DUF2115 PF09888.9 CRK19375.1 - 0.048 14.2 1.2 0.12 12.9 1.2 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) LMBR1 PF04791.16 CRK19375.1 - 0.13 11.2 0.9 0.14 11.0 0.9 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF948 PF06103.11 CRK19375.1 - 0.15 12.4 5.2 8 6.8 0.4 3.6 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Syntaxin_2 PF14523.6 CRK19375.1 - 0.23 11.8 12.2 0.19 12.1 4.5 3.1 2 1 1 3 3 3 0 Syntaxin-like protein Atg14 PF10186.9 CRK19375.1 - 0.38 9.8 5.8 0.3 10.1 1.7 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 MscS_porin PF12795.7 CRK19375.1 - 0.44 10.0 24.9 0.8 9.2 3.6 2.7 3 0 0 3 3 3 0 Mechanosensitive ion channel porin domain Ran-binding PF05508.11 CRK19375.1 - 0.55 9.2 9.2 0.27 10.2 3.7 2.1 1 1 1 2 2 2 0 RanGTP-binding protein FOXP-CC PF16159.5 CRK19375.1 - 1.1 9.9 9.7 0.56 10.9 0.5 3.2 3 0 0 3 3 3 0 FOXP coiled-coil domain BST2 PF16716.5 CRK19375.1 - 1.8 9.2 25.3 0.047 14.3 5.4 3.4 4 0 0 4 4 3 0 Bone marrow stromal antigen 2 SlyX PF04102.12 CRK19375.1 - 2.2 9.0 22.3 0.11 13.2 2.7 3.8 3 1 1 4 4 4 0 SlyX ABC_tran_CTD PF16326.5 CRK19375.1 - 2.5 8.4 17.5 4.6 7.6 3.6 3.9 3 1 1 4 4 4 0 ABC transporter C-terminal domain CDC37_N PF03234.14 CRK19375.1 - 2.8 8.9 10.7 0.76 10.7 6.8 2.0 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding COG5 PF10392.9 CRK19375.1 - 3.4 7.8 13.3 2.8 8.1 0.5 2.5 2 1 0 2 2 2 0 Golgi transport complex subunit 5 AAA_11 PF13086.6 CRK19375.1 - 3.5 7.4 8.4 1.7 8.4 4.3 2.0 2 0 0 2 2 2 0 AAA domain Swi5 PF07061.11 CRK19375.1 - 3.7 7.7 9.6 1.7 8.8 0.2 3.2 2 1 0 2 2 2 0 Swi5 FapA PF03961.13 CRK19375.1 - 4.1 5.9 7.0 16 3.9 4.0 2.2 2 0 0 2 2 2 0 Flagellar Assembly Protein A Spc24 PF08286.11 CRK19375.1 - 4.8 7.5 15.0 0.62 10.3 0.3 2.8 3 1 0 3 3 2 0 Spc24 subunit of Ndc80 DUF1043 PF06295.12 CRK19375.1 - 6 6.9 15.5 2.1 8.4 0.5 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1043) Glutaredoxin2_C PF04399.13 CRK19375.1 - 7.7 6.4 7.7 1.5 8.6 0.3 2.8 2 1 1 3 3 3 0 Glutaredoxin 2, C terminal domain HSCB_C PF07743.13 CRK19375.1 - 8.4 7.0 12.9 4.3 7.9 1.2 3.9 3 1 1 4 4 4 0 HSCB C-terminal oligomerisation domain HTH_35 PF13693.6 CRK19376.1 - 0.22 11.6 1.9 12 6.0 0.0 3.4 4 0 0 4 4 4 0 Winged helix-turn-helix DNA-binding dUTPase PF00692.19 CRK19378.1 - 7.5e-43 145.3 0.0 1.1e-42 144.8 0.0 1.2 1 0 0 1 1 1 1 dUTPase dUTPase PF00692.19 CRK19383.1 - 7.4e-43 145.3 0.0 1.1e-42 144.8 0.0 1.2 1 0 0 1 1 1 1 dUTPase Phos_pyr_kin PF08543.12 CRK19384.1 - 2e-11 43.8 0.0 2.7e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 CRK19384.1 - 4.1e-08 32.9 0.8 1.9e-07 30.7 0.0 2.3 3 0 0 3 3 3 1 pfkB family carbohydrate kinase Ribosomal_S30 PF04758.14 CRK19386.1 - 1.4e-28 98.9 5.5 1.5e-28 98.8 5.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 PCNA_N PF00705.18 CRK19388.1 - 4.2e-53 178.4 5.5 7.9e-53 177.5 3.1 2.0 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 CRK19388.1 - 1.2e-46 158.0 0.0 2.2e-45 153.9 0.0 2.0 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 CRK19388.1 - 1.2e-11 44.5 0.0 1.4e-11 44.3 0.0 1.0 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.12 CRK19388.1 - 3.4e-06 26.4 0.1 4.8e-05 22.6 0.1 2.4 1 1 0 1 1 1 1 Hus1-like protein HLH PF00010.26 CRK19388.1 - 0.12 12.3 0.2 0.21 11.6 0.2 1.3 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain Vezatin PF12632.7 CRK19390.1 - 4.5e-76 255.9 0.0 7.6e-76 255.1 0.0 1.3 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes DUF4231 PF14015.6 CRK19390.1 - 0.23 12.0 3.0 0.5 10.9 1.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Acyl-CoA_dh_1 PF00441.24 CRK19392.1 - 5.1e-13 49.5 1.1 1.3e-10 41.6 0.8 3.1 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain AidB_N PF18158.1 CRK19392.1 - 7.9e-12 45.4 0.1 1.4e-11 44.6 0.1 1.4 1 0 0 1 1 1 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_M PF02770.19 CRK19392.1 - 5.8e-11 42.5 0.1 4.4e-10 39.6 0.1 2.4 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain AMP-binding_C PF13193.6 CRK19394.1 - 7.7e-06 26.8 0.1 2.3e-05 25.3 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Fungal_trans PF04082.18 CRK19395.1 - 4.5e-12 45.6 0.5 6.9e-12 44.9 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK19395.1 - 2e-05 24.6 13.6 3.4e-05 23.9 13.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RabGAP-TBC PF00566.18 CRK19398.1 - 7e-47 159.9 0.0 1.1e-46 159.2 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain LRR_4 PF12799.7 CRK19400.1 - 3.8e-26 90.7 17.6 2.4e-06 27.7 5.3 6.2 5 1 1 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CRK19400.1 - 8.5e-18 63.9 15.1 3.1e-05 23.6 3.8 5.7 4 2 2 6 6 6 4 Leucine rich repeat LRR_9 PF14580.6 CRK19400.1 - 1.1e-10 41.3 8.0 1.3e-05 24.8 0.4 3.2 2 1 1 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 CRK19400.1 - 5.6e-05 22.9 12.0 1.4 9.2 0.0 6.5 7 0 0 7 7 7 3 Leucine Rich repeat LRR_1 PF00560.33 CRK19400.1 - 0.00029 21.0 20.5 9 7.3 0.2 8.4 6 3 0 6 6 6 1 Leucine Rich Repeat FAD_binding_2 PF00890.24 CRK19449.1 - 1.5e-33 116.5 0.2 1.7e-33 116.3 0.2 1.1 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 CRK19449.1 - 0.0011 18.3 0.1 0.0017 17.7 0.1 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 CRK19449.1 - 0.0012 18.1 0.1 0.0019 17.6 0.1 1.3 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 CRK19449.1 - 0.0033 16.7 0.0 0.0038 16.5 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CRK19449.1 - 0.0046 16.1 1.2 0.0058 15.8 1.2 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A DAO PF01266.24 CRK19449.1 - 0.0096 15.5 0.1 0.011 15.4 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 CRK19449.1 - 0.061 12.0 0.1 0.076 11.7 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_8 PF13450.6 CRK19449.1 - 0.062 13.5 0.1 0.1 12.9 0.1 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain PFK PF00365.20 CRK19467.1 - 5.7e-11 42.3 0.5 1e-10 41.4 0.1 1.5 2 0 0 2 2 2 1 Phosphofructokinase UVR PF02151.19 CRK19467.1 - 0.014 15.1 0.1 0.025 14.3 0.1 1.4 1 0 0 1 1 1 0 UvrB/uvrC motif DUF211 PF02680.14 CRK19467.1 - 0.019 15.1 0.0 0.023 14.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized ArCR, COG1888 NolB PF17398.2 CRK19467.1 - 0.095 13.1 0.1 0.11 12.8 0.1 1.1 1 0 0 1 1 1 0 Nodulation protein NolB Gcd10p PF04189.13 CRK19475.1 - 7.7e-114 379.8 0.0 9.3e-114 379.6 0.0 1.1 1 0 0 1 1 1 1 Gcd10p family Pox_I3 PF04661.12 CRK19475.1 - 0.013 14.7 0.0 0.022 13.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus I3 ssDNA-binding protein P21-Arc PF04062.14 CRK19476.1 - 5.6e-72 241.4 0.0 6.5e-72 241.2 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit GrpB PF04229.14 CRK19478.1 - 1.2e-38 132.8 0.0 2.1e-38 132.0 0.0 1.4 1 0 0 1 1 1 1 GrpB protein HATPase_c PF02518.26 CRK19478.1 - 7.1e-21 74.8 0.0 1.6e-20 73.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 CRK19478.1 - 1.3e-16 60.8 0.0 5.7e-16 58.7 0.0 2.1 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 CRK19478.1 - 1.4e-11 44.2 0.2 4.1e-11 42.8 0.2 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain ThiG PF05690.14 CRK19478.1 - 0.038 13.3 0.1 0.11 11.8 0.0 1.7 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG PHO4 PF01384.20 CRK19479.1 - 6.8e-110 367.3 18.2 7.8e-110 367.1 18.2 1.0 1 0 0 1 1 1 1 Phosphate transporter family RdRP PF05183.12 CRK19480.1 - 1.2e-184 615.3 0.0 1.6e-184 614.9 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase R3H PF01424.22 CRK19481.1 - 5.6e-11 42.3 0.3 1.1e-10 41.3 0.3 1.5 1 0 0 1 1 1 1 R3H domain RRM_1 PF00076.22 CRK19481.1 - 0.00012 21.8 0.0 0.00034 20.4 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TRAP_alpha PF03896.16 CRK19482.1 - 0.21 10.7 1.7 0.23 10.6 1.7 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CENP-B_dimeris PF09026.10 CRK19482.1 - 0.28 11.6 11.0 0.37 11.2 11.0 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PTPRCAP PF15713.5 CRK19482.1 - 0.5 10.6 11.2 0.69 10.2 11.2 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated RXT2_N PF08595.11 CRK19482.1 - 0.53 10.3 4.7 0.64 10.0 4.7 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.12 CRK19482.1 - 0.87 8.9 11.8 1.1 8.5 11.8 1.2 1 0 0 1 1 1 0 NOA36 protein Radial_spoke PF04712.12 CRK19482.1 - 1.1 8.1 8.7 1.3 7.9 8.7 1.0 1 0 0 1 1 1 0 Radial spokehead-like protein Cytomega_UL84 PF06284.11 CRK19482.1 - 1.5 7.2 5.0 1.6 7.1 5.0 1.0 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein EBV-NA3 PF05009.12 CRK19482.1 - 1.6 8.2 3.3 2 7.9 3.3 1.2 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) DNA_pol_phi PF04931.13 CRK19482.1 - 2.2 6.2 12.7 2.5 6.1 12.7 1.0 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 CRK19482.1 - 2.7 7.3 10.3 3.3 7.0 10.3 1.0 1 0 0 1 1 1 0 SDA1 Astro_capsid_p PF12226.8 CRK19482.1 - 3.5 6.7 10.8 3.9 6.5 10.8 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Myc_N PF01056.18 CRK19482.1 - 3.7 7.4 8.7 4.7 7.0 8.7 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Sigma70_ner PF04546.13 CRK19482.1 - 4.4 7.1 10.1 5.2 6.9 10.1 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region Nop14 PF04147.12 CRK19482.1 - 6.4 4.9 11.5 7.1 4.7 11.5 1.0 1 0 0 1 1 1 0 Nop14-like family COPI_C PF06957.11 CRK19482.1 - 7.2 5.3 7.4 8.1 5.1 7.4 1.0 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus NR_Repeat PF14046.6 CRK19483.1 - 0.49 10.6 3.5 2.5 8.3 3.5 2.1 1 1 0 1 1 1 0 Nuclear receptor repeat Ank_2 PF12796.7 CRK19484.1 - 4.8e-20 71.9 0.0 1e-12 48.4 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Histone PF00125.24 CRK19484.1 - 2.1e-16 60.5 0.0 3.6e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Ank_5 PF13857.6 CRK19484.1 - 6.5e-14 51.8 0.6 2.6e-10 40.3 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 CRK19484.1 - 1.7e-13 50.4 2.7 1e-06 28.9 0.0 4.5 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 CRK19484.1 - 1.7e-13 50.8 0.6 3.4e-09 37.1 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CRK19484.1 - 5.4e-13 47.9 0.3 8.8e-06 25.7 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat Histone_H2A_C PF16211.5 CRK19484.1 - 6e-12 45.1 0.1 1.2e-11 44.1 0.1 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 CRK19484.1 - 0.0012 19.1 0.1 0.0028 17.9 0.0 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone APH PF01636.23 CRK19485.1 - 5e-15 56.1 0.1 1.5e-14 54.5 0.1 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CRK19485.1 - 0.0001 21.9 0.0 0.00019 21.1 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.11 CRK19485.1 - 0.01 14.7 0.0 0.031 13.1 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) EcKinase PF02958.20 CRK19485.1 - 0.014 14.7 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase RIO1 PF01163.22 CRK19485.1 - 0.061 12.9 0.0 2.8 7.5 0.0 2.7 3 0 0 3 3 3 0 RIO1 family Helo_like_N PF17111.5 CRK19486.1 - 0.0061 16.0 0.0 0.0099 15.3 0.0 1.6 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins APH PF01636.23 CRK19488.1 - 2.9e-10 40.5 0.2 3.6e-10 40.2 0.2 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CRK19488.1 - 1.7e-05 24.5 0.0 2.3e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 CRK19488.1 - 0.0068 15.8 0.0 0.0096 15.3 0.0 1.1 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 CRK19488.1 - 0.0093 14.9 0.1 0.013 14.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) APH PF01636.23 CRK19490.1 - 5.1e-07 29.9 0.0 1.1e-05 25.4 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family p450 PF00067.22 CRK19491.1 - 1.1e-41 143.0 0.0 7.1e-41 140.4 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 RTA1 PF04479.13 CRK19492.1 - 6.6e-65 218.6 1.4 1e-64 217.9 1.4 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF4328 PF14219.6 CRK19492.1 - 0.29 10.7 7.9 1.9 8.0 0.4 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4328) Gly_transf_sug PF04488.15 CRK19493.1 - 1.7e-16 60.6 0.1 2.9e-16 59.9 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 CRK19493.1 - 0.017 14.5 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein Glyco_hydro_6 PF01341.17 CRK19494.1 - 2e-94 316.7 0.2 3.3e-94 316.1 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 COesterase PF00135.28 CRK19494.1 - 6.8e-81 272.7 0.0 1.2e-80 271.9 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family DUF4863 PF16155.5 CRK19494.1 - 2.6e-68 228.7 0.0 4.5e-68 227.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4863) PAP2_3 PF14378.6 CRK19494.1 - 2.3e-22 79.6 22.6 6e-22 78.3 18.7 2.9 2 1 0 2 2 2 1 PAP2 superfamily Abhydrolase_3 PF07859.13 CRK19494.1 - 8.1e-05 22.6 0.1 0.00038 20.4 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Glyco_hydro_28 PF00295.17 CRK19495.1 - 8e-31 107.3 1.5 1.2e-30 106.8 1.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 NosD PF05048.13 CRK19495.1 - 0.017 14.4 3.5 0.031 13.5 3.5 1.4 1 0 0 1 1 1 0 Periplasmic copper-binding protein (NosD) Beta_helix PF13229.6 CRK19495.1 - 0.17 11.7 6.0 0.47 10.3 6.2 1.6 1 1 0 1 1 1 0 Right handed beta helix region Sulfate_transp PF00916.20 CRK19496.1 - 2.2e-110 369.0 19.7 3e-110 368.6 19.7 1.2 1 0 0 1 1 1 1 Sulfate permease family adh_short PF00106.25 CRK19496.1 - 1.4e-27 96.5 1.3 4e-25 88.4 0.3 2.9 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 CRK19496.1 - 2.6e-16 59.9 0.7 1.7e-14 53.9 0.7 2.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK19496.1 - 1.5e-05 25.0 0.2 3.2e-05 23.9 0.2 1.5 1 0 0 1 1 1 1 KR domain MFS_MOT1 PF16983.5 CRK19496.1 - 1.9e-05 25.0 14.6 3.5e-05 24.2 3.8 3.3 2 2 0 2 2 2 2 Molybdate transporter of MFS superfamily YdjM PF04307.14 CRK19496.1 - 0.0012 18.1 0.0 0.0072 15.6 0.0 2.2 1 1 0 2 2 2 1 LexA-binding, inner membrane-associated putative hydrolase His_Phos_1 PF00300.22 CRK19499.1 - 1.5e-26 93.3 0.3 5.2e-26 91.5 0.3 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) CVNH PF08881.10 CRK19499.1 - 5e-06 27.1 0.1 1.1e-05 26.1 0.1 1.5 1 0 0 1 1 1 1 CVNH domain WRC PF08879.10 CRK19499.1 - 0.024 14.3 1.1 0.048 13.4 1.1 1.4 1 0 0 1 1 1 0 WRC ERCC4 PF02732.15 CRK19500.1 - 1.1e-25 90.6 0.0 2.2e-25 89.7 0.0 1.5 1 0 0 1 1 1 1 ERCC4 domain Kinesin PF00225.23 CRK19501.1 - 5.8e-19 68.2 0.0 6.2e-19 68.1 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CRK19501.1 - 7.3e-18 64.9 0.0 1e-17 64.5 0.0 1.1 1 0 0 1 1 1 1 Microtubule binding Ribosomal_L6 PF00347.23 CRK19505.1 - 6e-09 36.5 0.4 7.5e-06 26.5 0.0 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Pribosyl_synth PF14572.6 CRK19506.1 - 1.8e-13 51.0 0.0 2.2e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 CRK19506.1 - 1.5e-05 24.6 0.0 1.7e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CRK19506.1 - 0.03 13.8 0.0 0.042 13.3 0.0 1.1 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Glyco_hydro_31 PF01055.26 CRK19508.1 - 2.3e-20 73.2 0.0 2.5e-20 73.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Glyco_hydro_3 PF00933.21 CRK19509.1 - 0.00022 20.7 0.0 0.00031 20.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain DUF1707 PF08044.11 CRK19509.1 - 0.052 13.6 0.0 0.081 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1707) Metalloenzyme PF01676.18 CRK19511.1 - 2.2e-25 89.5 0.4 4.8e-18 65.4 0.1 2.0 1 1 1 2 2 2 2 Metalloenzyme superfamily Sulfatase PF00884.23 CRK19511.1 - 0.036 13.4 0.0 0.044 13.2 0.0 1.2 1 1 0 1 1 1 0 Sulfatase Bax1-I PF01027.20 CRK19515.1 - 6.8e-17 62.0 0.2 7.4e-17 61.9 0.2 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Arf PF00025.21 CRK19518.1 - 2e-37 128.3 0.4 2.2e-37 128.2 0.4 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CRK19518.1 - 2.3e-10 40.8 0.1 2.4e-10 40.7 0.1 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 CRK19518.1 - 7e-09 35.3 0.4 9.9e-09 34.8 0.4 1.3 1 1 0 1 1 1 1 G-protein alpha subunit Ras PF00071.22 CRK19518.1 - 4.9e-08 32.7 0.0 5.3e-08 32.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 CRK19518.1 - 8.4e-07 28.6 0.1 9.6e-07 28.4 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 CRK19518.1 - 1.1e-05 24.9 0.0 1.2e-05 24.8 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CRK19518.1 - 0.007 16.4 0.0 0.0077 16.3 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Tachylectin PF14517.6 CRK19518.1 - 0.16 11.5 0.0 0.17 11.4 0.0 1.0 1 0 0 1 1 1 0 Tachylectin RNA_pol_Rpb2_6 PF00562.28 CRK19547.1 - 2.1e-32 112.7 0.0 2.3e-32 112.5 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 Ist1 PF03398.14 CRK19549.1 - 3.9e-39 134.2 3.6 4.3e-39 134.1 3.6 1.0 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway TFIIA PF03153.13 CRK19552.1 - 2.2 8.2 25.9 3.3 7.6 25.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit p450 PF00067.22 CRK19553.1 - 2.7e-62 211.0 0.0 3.4e-62 210.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.18 CRK19554.1 - 4.1e-05 23.6 7.5 4.1e-05 23.6 7.5 3.4 4 0 0 4 4 4 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 CRK19554.1 - 0.00094 19.5 2.6 0.00094 19.5 2.6 4.5 4 1 1 5 5 5 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CRK19554.1 - 0.001 19.4 16.0 0.0013 19.1 1.9 3.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 CRK19554.1 - 0.0032 18.2 1.7 0.0032 18.2 1.7 4.1 4 1 1 5 5 5 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CRK19554.1 - 0.011 15.7 1.8 0.011 15.7 1.8 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CRK19554.1 - 0.061 13.6 5.3 0.15 12.4 0.4 2.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 CRK19554.1 - 0.087 12.9 11.3 1.8 8.7 0.6 2.5 1 1 1 2 2 2 0 BED zinc finger p450 PF00067.22 CRK19555.1 - 2.4e-27 95.8 0.0 3e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_L27 PF01016.19 CRK19557.1 - 6.8e-27 93.3 0.0 6.8e-27 93.3 0.0 1.9 2 0 0 2 2 2 1 Ribosomal L27 protein Cupin_3 PF05899.12 CRK19558.1 - 0.16 11.7 0.0 0.56 9.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Aldolase_II PF00596.21 CRK19559.1 - 3.7e-29 102.0 1.0 4.5e-29 101.7 1.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain SET PF00856.28 CRK19560.1 - 6.8e-12 46.1 0.0 1.2e-11 45.3 0.0 1.4 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 CRK19560.1 - 5.3e-10 40.1 0.6 1.2e-09 38.9 0.6 1.8 1 1 0 1 1 1 1 Rubisco LSMT substrate-binding Adap_comp_sub PF00928.21 CRK19561.1 - 2.5e-90 302.5 0.0 4.5e-90 301.6 0.0 1.4 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CRK19561.1 - 4.8e-09 36.3 0.2 7.7e-09 35.6 0.2 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Opi1 PF08618.10 CRK19562.1 - 1.9e-36 126.2 7.7 4.7e-25 88.7 0.7 3.1 2 1 1 3 3 3 3 Transcription factor Opi1 2-Hacid_dh_C PF02826.19 CRK19562.1 - 2e-36 125.0 0.1 3.4e-36 124.3 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 CRK19562.1 - 0.001 19.3 0.0 0.002 18.3 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 CRK19562.1 - 0.031 14.9 0.0 0.11 13.1 0.0 2.0 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent HAT_KAT11 PF08214.11 CRK19563.1 - 2e-95 320.1 0.0 2.5e-95 319.7 0.0 1.1 1 0 0 1 1 1 1 Histone acetylation protein Pneumo_att_G PF05539.11 CRK19563.1 - 1.2 8.7 7.1 1.8 8.1 7.1 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Ribonucleas_3_3 PF14622.6 CRK19564.1 - 2.6e-30 105.2 0.0 5.1e-30 104.3 0.0 1.5 1 1 0 1 1 1 1 Ribonuclease-III-like Thymidylate_kin PF02223.17 CRK19565.1 - 3.9e-40 137.5 0.0 5.7e-39 133.7 0.0 2.1 2 0 0 2 2 2 1 Thymidylate kinase Asp PF00026.23 CRK19565.1 - 3e-19 69.6 0.0 9.4e-17 61.4 0.0 2.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease AAA_28 PF13521.6 CRK19565.1 - 0.0037 17.5 0.0 0.0068 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 CRK19565.1 - 0.024 14.1 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Glyco_hydro_28 PF00295.17 CRK19566.1 - 5.2e-114 380.7 21.0 6.1e-114 380.4 21.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 YajC PF02699.15 CRK19566.1 - 0.83 9.6 2.3 4.2 7.3 0.5 2.8 3 0 0 3 3 3 0 Preprotein translocase subunit adh_short PF00106.25 CRK19569.1 - 3.6e-08 33.1 0.0 0.011 15.3 0.0 3.1 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.10 CRK19569.1 - 0.011 15.6 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 0 KR domain adh_short_C2 PF13561.6 CRK19569.1 - 0.031 13.8 0.0 0.65 9.5 0.0 2.7 1 1 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.15 CRK19569.1 - 0.2 10.8 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein AMP-binding PF00501.28 CRK19570.1 - 3.6e-28 98.3 0.0 7.3e-28 97.3 0.0 1.4 1 1 1 2 2 2 1 AMP-binding enzyme Thiolase_N PF00108.23 CRK19571.1 - 2.1e-64 217.4 0.0 3.2e-64 216.8 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CRK19571.1 - 2.2e-39 133.9 0.1 5e-39 132.7 0.1 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain Fungal_trans PF04082.18 CRK19571.1 - 2.3e-13 49.8 0.2 3.3e-13 49.3 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ketoacyl-synt PF00109.26 CRK19571.1 - 0.02 14.5 0.4 0.058 13.0 0.4 1.7 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain adh_short PF00106.25 CRK19572.1 - 5.7e-73 244.5 10.8 4.3e-42 143.8 1.3 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CRK19572.1 - 1.4e-58 198.2 12.3 5.2e-34 117.8 2.1 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 CRK19572.1 - 7.2e-30 103.1 0.0 2.3e-29 101.5 0.0 1.8 1 0 0 1 1 1 1 MaoC like domain KR PF08659.10 CRK19572.1 - 9.7e-18 64.7 9.0 6.6e-12 45.7 0.5 2.4 2 0 0 2 2 2 2 KR domain MaoC_dehydrat_N PF13452.6 CRK19572.1 - 0.00019 21.6 0.0 0.00069 19.8 0.0 1.9 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase THF_DHG_CYH_C PF02882.19 CRK19572.1 - 0.008 15.5 0.4 0.22 10.9 0.2 2.7 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain FAD_binding_3 PF01494.19 CRK19574.1 - 3.8e-13 49.4 0.0 1.2e-12 47.7 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 CRK19574.1 - 0.0054 15.8 0.0 0.0089 15.1 0.0 1.4 1 0 0 1 1 1 1 Squalene epoxidase NAD_binding_8 PF13450.6 CRK19574.1 - 0.039 14.2 0.0 0.089 13.0 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Aldedh PF00171.22 CRK19575.1 - 1.5e-140 468.8 0.0 1.7e-140 468.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family FAD_binding_4 PF01565.23 CRK19576.1 - 3.7e-22 78.5 1.1 7.8e-22 77.5 1.1 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 CRK19576.1 - 0.079 13.1 0.0 0.22 11.6 0.0 1.8 1 0 0 1 1 1 0 Berberine and berberine like RTA1 PF04479.13 CRK19577.1 - 1.4e-55 188.2 7.1 2.3e-55 187.4 7.1 1.3 1 0 0 1 1 1 1 RTA1 like protein UL41A PF17591.2 CRK19577.1 - 0.062 13.4 0.1 0.35 11.0 0.0 2.2 2 0 0 2 2 2 0 Herpesvirus UL41A ThrE PF06738.12 CRK19578.1 - 5e-61 206.1 24.1 2.6e-58 197.2 4.5 2.8 3 0 0 3 3 3 2 Putative threonine/serine exporter ThrE_2 PF12821.7 CRK19578.1 - 2e-11 44.2 13.9 2e-11 44.2 13.9 2.4 2 0 0 2 2 2 1 Threonine/Serine exporter, ThrE Peptidase_M13_N PF05649.13 CRK19579.1 - 2.9e-97 326.8 0.0 3.9e-97 326.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 CRK19579.1 - 1.5e-62 210.9 0.8 4.7e-62 209.2 0.2 1.9 2 0 0 2 2 2 1 Peptidase family M13 adh_short PF00106.25 CRK19580.1 - 1.7e-29 102.7 1.5 4.6e-22 78.4 0.6 2.2 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CRK19580.1 - 2.1e-18 66.8 0.6 2.8e-13 50.0 0.2 2.3 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 CRK19580.1 - 3.8e-07 29.8 0.0 5.6e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 CRK19580.1 - 4.2e-05 23.5 0.0 8.3e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 CRK19580.1 - 0.02 14.5 0.1 0.029 13.9 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family Epimerase PF01370.21 CRK19580.1 - 0.025 14.1 0.1 0.059 12.8 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 CRK19580.1 - 0.046 14.0 0.1 0.072 13.4 0.1 1.3 1 0 0 1 1 1 0 TrkA-N domain SAM_decarbox PF01536.16 CRK19582.1 - 3.1e-136 454.1 0.0 3.9e-136 453.7 0.0 1.1 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase Sorting_nexin PF03700.13 CRK19582.1 - 0.14 12.8 1.4 0.26 11.8 1.4 1.4 1 0 0 1 1 1 0 Sorting nexin, N-terminal domain GFO_IDH_MocA PF01408.22 CRK19583.1 - 4.4e-16 59.8 0.0 6.7e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 CRK19583.1 - 0.038 14.6 0.0 0.094 13.4 0.0 1.7 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain Sugar_tr PF00083.24 CRK19584.1 - 1.7e-89 300.7 23.8 2e-89 300.5 23.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK19584.1 - 6.2e-37 127.3 53.0 1.4e-26 93.3 28.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CRK19584.1 - 1.2e-07 30.6 0.7 1.2e-07 30.6 0.7 2.8 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF4133 PF13571.6 CRK19584.1 - 7.7 6.9 13.9 2 8.8 0.8 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF4133) Rft-1 PF04506.13 CRK19585.1 - 0.017 13.9 4.0 0.02 13.7 4.0 1.1 1 0 0 1 1 1 0 Rft protein DUF3671 PF12420.8 CRK19585.1 - 3.3 7.8 4.3 8.8 6.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF2070 PF09843.9 CRK19585.1 - 3.6 5.8 10.2 4.8 5.3 10.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) adh_short_C2 PF13561.6 CRK19588.1 - 4.8e-20 72.1 0.0 5.1e-20 72.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRK19588.1 - 1e-17 64.2 0.1 1.2e-17 64.0 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase AMPK1_CBM PF16561.5 CRK19590.1 - 0.00033 20.8 0.5 0.00052 20.2 0.5 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Mannosyl_trans3 PF11051.8 CRK19593.1 - 0.016 14.6 0.0 0.016 14.6 0.0 1.1 1 0 0 1 1 1 0 Mannosyltransferase putative Sugar_tr PF00083.24 CRK19607.1 - 0.00021 20.3 0.3 0.00022 20.2 0.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter 7TMR-DISM_7TM PF07695.11 CRK19607.1 - 0.038 13.9 0.3 0.04 13.8 0.3 1.1 1 0 0 1 1 1 0 7TM diverse intracellular signalling WD40 PF00400.32 CRK19608.1 - 0.00012 22.8 0.5 0.034 15.0 0.0 2.6 2 1 1 3 3 3 2 WD domain, G-beta repeat PD40 PF07676.12 CRK19608.1 - 0.0025 17.7 0.1 0.012 15.5 0.0 2.0 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat SpoU_methylase PF00588.19 CRK19623.1 - 4.5e-26 91.7 0.0 5.1e-26 91.5 0.0 1.0 1 0 0 1 1 1 1 SpoU rRNA Methylase family Methyltrn_RNA_4 PF09936.9 CRK19623.1 - 0.061 13.2 0.0 0.087 12.7 0.0 1.2 1 1 0 1 1 1 0 SAM-dependent RNA methyltransferase FOXP-CC PF16159.5 CRK19628.1 - 0.012 16.3 4.8 0.034 14.8 4.1 2.2 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2 PF00096.26 CRK19628.1 - 0.025 15.0 0.9 0.025 15.0 0.9 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf_C2H2_10 PF18414.1 CRK19628.1 - 0.71 9.5 3.0 1.4 8.5 3.0 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger CDC27 PF09507.10 CRK19628.1 - 9.2 5.5 19.2 20 4.4 19.2 1.5 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Iso_dh PF00180.20 CRK19629.1 - 2.5e-51 174.9 0.0 3.5e-51 174.4 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Ino80_Iec3 PF14612.6 CRK19629.1 - 1e-45 157.3 7.8 2.3e-25 90.7 0.3 2.2 1 1 1 2 2 2 2 IEC3 subunit of the Ino80 complex, chromatin re-modelling Ino80_Iec3 PF14612.6 CRK19630.1 - 4.1e-55 188.0 8.5 5.1e-28 99.3 3.1 2.2 1 1 1 2 2 2 2 IEC3 subunit of the Ino80 complex, chromatin re-modelling UPF0160 PF03690.13 CRK19632.1 - 1.3e-130 435.7 0.0 1.5e-130 435.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Endosulfine PF04667.17 CRK19634.1 - 6.3e-26 90.3 0.0 1.2e-25 89.4 0.0 1.4 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region MFS_1 PF07690.16 CRK19634.1 - 3.7e-18 65.6 39.6 2.7e-12 46.3 20.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 CRK19635.1 - 5e-30 104.6 50.0 3.1e-25 88.9 27.5 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 CRK19635.1 - 7.8e-12 44.5 21.5 0.00038 19.1 3.0 3.4 3 1 1 4 4 4 3 MFS/sugar transport protein MFS_1_like PF12832.7 CRK19635.1 - 3.4e-07 29.5 11.1 3.5e-05 22.9 3.4 2.2 2 0 0 2 2 2 2 MFS_1 like family OATP PF03137.20 CRK19635.1 - 0.0038 15.6 3.8 0.029 12.7 2.2 2.2 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 CRK19635.1 - 0.016 14.1 15.3 0.036 12.9 12.4 2.5 2 1 0 2 2 2 0 Sugar (and other) transporter UTP15_C PF09384.10 CRK19637.1 - 1.4e-42 144.8 0.0 3.9e-33 114.2 0.0 2.3 2 0 0 2 2 2 2 UTP15 C terminal WD40 PF00400.32 CRK19637.1 - 1.7e-18 66.6 4.6 2.1e-05 25.2 0.0 5.9 7 1 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK19637.1 - 2.3e-07 31.0 0.1 0.096 13.0 0.0 4.2 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain HPS3_N PF14761.6 CRK19637.1 - 0.0034 17.0 0.0 3.7 7.0 0.0 2.6 2 1 0 2 2 2 2 Hermansky-Pudlak syndrome 3 DUF5122 PF17164.4 CRK19637.1 - 0.046 14.0 0.9 4.1 7.8 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5122) beta-propeller Nup160 PF11715.8 CRK19637.1 - 0.091 11.4 0.3 0.63 8.6 0.1 2.3 2 1 1 3 3 3 0 Nucleoporin Nup120/160 BclA_C PF18573.1 CRK19637.1 - 0.19 11.6 0.8 33 4.4 0.1 2.8 2 1 1 3 3 3 0 BclA C-terminal domain C2 PF00168.30 CRK19638.1 - 5.6e-17 61.9 0.0 9e-17 61.3 0.0 1.3 1 0 0 1 1 1 1 C2 domain SIS PF01380.22 CRK19639.1 - 6.9e-11 42.1 0.0 1.6e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 SIS domain CBS PF00571.28 CRK19639.1 - 0.037 14.5 1.2 0.69 10.4 1.2 2.6 1 1 0 1 1 1 0 CBS domain L_HMGIC_fpl PF10242.9 CRK19640.1 - 0.00014 22.2 5.0 0.00029 21.1 5.0 1.5 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Fzo_mitofusin PF04799.13 CRK19640.1 - 0.071 12.6 0.9 0.16 11.5 0.9 1.6 1 0 0 1 1 1 0 fzo-like conserved region DUF2516 PF10724.9 CRK19640.1 - 2.8 8.3 8.4 0.69 10.2 0.9 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2516) DUF5422 PF17459.2 CRK19640.1 - 5.2 7.3 9.0 0.57 10.4 0.8 2.4 1 1 0 2 2 2 0 Family of unknown function (DUF5422) DUF2373 PF10180.9 CRK19641.1 - 1.9e-23 82.0 0.3 3.3e-23 81.3 0.3 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Nop14 PF04147.12 CRK19641.1 - 0.3 9.3 37.5 0.42 8.8 37.5 1.1 1 0 0 1 1 1 0 Nop14-like family Rotamase PF00639.21 CRK19641.1 - 1.7 9.7 5.6 2 9.4 3.2 2.4 2 0 0 2 2 2 0 PPIC-type PPIASE domain Proteasome PF00227.26 CRK19642.1 - 3.5e-49 166.9 0.0 5e-49 166.4 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CRK19642.1 - 1.1e-13 50.6 0.3 2.1e-13 49.6 0.3 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature CIAPIN1 PF05093.13 CRK19643.1 - 1.6e-40 137.6 3.1 2.7e-40 136.9 3.1 1.3 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 CRK19643.1 - 4.8e-34 117.4 0.0 6.9e-34 116.9 0.0 1.2 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus Peptidase_S10 PF00450.22 CRK19644.1 - 7.8e-31 107.9 0.0 1e-30 107.5 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase GRA6 PF05084.13 CRK19644.1 - 0.049 13.6 0.4 0.097 12.6 0.4 1.5 1 1 0 1 1 1 0 Granule antigen protein (GRA6) Secretogranin_V PF05281.11 CRK19645.1 - 0.042 13.5 0.0 0.06 13.0 0.0 1.2 1 0 0 1 1 1 0 Neuroendocrine protein 7B2 precursor (Secretogranin V) TMEM234 PF10639.9 CRK19646.1 - 1e-35 122.2 0.2 1.3e-35 121.9 0.2 1.1 1 0 0 1 1 1 1 Putative transmembrane family 234 EamA PF00892.20 CRK19646.1 - 0.00012 22.2 3.6 0.037 14.2 2.7 2.2 2 0 0 2 2 2 2 EamA-like transporter family DUF1211 PF06736.11 CRK19646.1 - 0.039 14.4 0.0 1.1 9.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1211) DUF485 PF04341.12 CRK19646.1 - 0.13 12.2 0.4 2 8.4 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function, DUF485 Con-6 PF10346.9 CRK19647.1 - 1.1e-32 111.7 5.3 1.9e-17 63.0 0.2 2.2 2 0 0 2 2 2 2 Conidiation protein 6 DUF1542 PF07564.11 CRK19647.1 - 0.013 15.6 3.0 1.1 9.4 0.0 2.3 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1542) SpoIIIAH PF12685.7 CRK19647.1 - 0.44 10.3 9.1 4.7 7.0 9.1 2.2 1 1 0 1 1 1 0 SpoIIIAH-like protein RNA_Me_trans PF04252.13 CRK19648.1 - 3.9e-81 271.4 0.0 4.4e-81 271.2 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Peptidase_S10 PF00450.22 CRK19649.1 - 1.6e-115 386.9 0.0 1.9e-115 386.6 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase CIAPIN1 PF05093.13 CRK19650.1 - 1.6e-40 137.7 3.1 2.7e-40 136.9 3.1 1.4 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 CRK19650.1 - 2e-34 118.7 0.0 2.9e-34 118.1 0.0 1.2 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus Fructosamin_kin PF03881.14 CRK19651.1 - 1.2e-30 106.7 0.0 1.7e-30 106.2 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 CRK19651.1 - 0.00012 22.1 1.3 0.00014 21.8 0.5 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 CRK19651.1 - 0.11 11.8 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase SPX PF03105.19 CRK19653.1 - 2.2e-13 50.9 6.2 4.1e-06 27.0 0.0 3.4 1 1 2 3 3 3 3 SPX domain CcmD PF04995.14 CRK19653.1 - 0.11 12.6 0.4 0.53 10.4 0.4 2.2 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) ORC6 PF05460.13 CRK19653.1 - 0.15 11.3 1.4 0.23 10.7 1.4 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) TMEM151 PF14857.6 CRK19654.1 - 0.084 11.8 0.3 0.21 10.5 0.3 1.6 1 0 0 1 1 1 0 TMEM151 family RabGAP-TBC PF00566.18 CRK19656.1 - 1.2e-49 168.9 0.0 1.9e-49 168.3 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SHNi-TPR PF10516.9 CRK19656.1 - 1.7e-13 49.8 1.5 6.2e-13 48.0 0.1 2.7 2 0 0 2 2 2 1 SHNi-TPR TPR_12 PF13424.6 CRK19656.1 - 0.0022 18.2 2.6 0.011 16.0 0.6 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 CRK19656.1 - 0.013 16.1 2.9 0.092 13.4 2.9 2.5 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_17 PF13431.6 CRK19656.1 - 0.035 14.5 0.0 0.17 12.3 0.0 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 CRK19656.1 - 2 9.4 5.2 2.1 9.4 1.7 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 CRK19656.1 - 9.9 6.6 10.0 1.9 8.8 2.8 3.4 5 0 0 5 5 5 0 Tetratricopeptide repeat LETM1 PF07766.13 CRK19658.1 - 0.0017 17.8 0.1 0.0061 15.9 0.0 1.8 2 0 0 2 2 2 1 LETM1-like protein RRM_1 PF00076.22 CRK19659.1 - 4.2e-36 122.6 0.3 1.6e-17 63.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CRK19659.1 - 1.7e-12 47.3 0.3 4.3e-05 23.6 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 CRK19659.1 - 4.2e-05 23.4 0.1 0.22 11.6 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 CRK19659.1 - 0.0086 16.1 0.1 5.1 7.2 0.0 2.6 2 0 0 2 2 2 2 RNA binding motif OB_RNB PF08206.11 CRK19659.1 - 0.073 12.8 1.0 5.4 6.8 0.3 2.9 2 1 0 2 2 2 0 Ribonuclease B OB domain GATase_6 PF13522.6 CRK19660.1 - 2.9e-09 37.2 0.0 6.1e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 CRK19660.1 - 7.7e-09 35.5 0.0 1.5e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 CRK19660.1 - 0.00045 19.8 0.0 0.00082 18.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Peptidase_M35 PF02102.15 CRK19661.1 - 3.9e-76 256.3 10.5 4.6e-76 256.0 10.5 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 CRK19661.1 - 7.2e-43 146.6 2.8 7.2e-43 146.6 2.8 1.7 1 1 1 2 2 2 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.6 CRK19661.1 - 0.1 12.1 6.5 0.16 11.5 6.5 1.4 1 1 0 1 1 1 0 Putative peptidase family Spermine_synth PF01564.17 CRK19662.1 - 1.4e-70 236.6 0.0 3.1e-70 235.4 0.0 1.5 2 0 0 2 2 2 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 CRK19662.1 - 8.4e-25 86.4 0.2 1.4e-24 85.8 0.2 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 CRK19662.1 - 0.0004 21.0 0.0 0.0011 19.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK19662.1 - 0.0014 18.5 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK19662.1 - 0.0065 17.2 0.5 0.052 14.3 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain DUF43 PF01861.16 CRK19662.1 - 0.017 14.4 0.0 0.027 13.7 0.0 1.3 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain G-alpha PF00503.20 CRK19663.1 - 1.1e-109 366.8 0.2 1.3e-109 366.6 0.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CRK19663.1 - 2.3e-13 50.0 1.3 2.7e-08 33.5 0.0 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CRK19663.1 - 0.00021 20.7 0.6 0.023 14.0 0.0 2.4 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region FtsK_SpoIIIE PF01580.18 CRK19663.1 - 0.023 14.1 0.0 0.037 13.4 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Roc PF08477.13 CRK19663.1 - 0.028 14.6 0.2 6.1 7.1 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_15 PF13175.6 CRK19663.1 - 0.046 13.4 0.5 0.097 12.4 0.2 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 CRK19663.1 - 0.14 11.9 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 CRK19663.1 - 0.14 11.7 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Glyco_hydro_3_C PF01915.22 CRK19664.1 - 8.8e-41 140.1 0.0 2.5e-40 138.6 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 CRK19664.1 - 3e-39 135.3 0.0 4.5e-39 134.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 CRK19664.1 - 1.7e-21 76.1 0.0 3.2e-21 75.2 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF4337 PF14235.6 CRK19667.1 - 5.3 7.1 11.5 3 7.9 3.1 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4337) TFA2_Winged_2 PF18121.1 CRK19669.1 - 4.2e-13 48.8 0.5 2.2e-12 46.5 0.2 2.0 2 0 0 2 2 2 1 TFA2 Winged helix domain 2 TBPIP PF07106.13 CRK19669.1 - 0.0003 20.7 0.4 0.0034 17.3 0.0 2.2 2 0 0 2 2 2 1 TBPIP/Hop2 winged helix domain TFIIE_beta PF02186.15 CRK19669.1 - 0.0005 20.3 0.4 0.0045 17.2 0.1 2.2 2 0 0 2 2 2 1 TFIIE beta subunit core domain E2_bind PF08825.10 CRK19669.1 - 0.0078 16.3 0.1 6.7 6.9 0.0 3.1 2 1 1 3 3 3 2 E2 binding domain DUF29 PF01724.16 CRK19669.1 - 0.077 13.2 0.3 0.52 10.5 0.1 2.2 2 1 0 2 2 2 0 Domain of unknown function DUF29 Aconitase PF00330.20 CRK19674.1 - 4.9e-33 114.8 0.0 5.4e-33 114.7 0.0 1.0 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) CLASP_N PF12348.8 CRK19676.1 - 2.7e-109 364.0 0.0 4.1e-72 242.4 0.0 2.0 2 0 0 2 2 2 2 CLASP N terminal HEAT PF02985.22 CRK19676.1 - 9.6e-06 25.4 0.1 3 8.4 0.0 4.9 5 0 0 5 5 5 2 HEAT repeat Cnd1 PF12717.7 CRK19676.1 - 0.00074 19.6 0.0 0.0058 16.7 0.0 2.4 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 CRK19676.1 - 0.0032 18.0 0.0 5 7.8 0.0 3.4 3 0 0 3 3 3 2 Vacuolar 14 Fab1-binding region Peptidase_M16_M PF16187.5 CRK19676.1 - 0.051 12.9 0.0 0.095 12.0 0.0 1.4 1 0 0 1 1 1 0 Middle or third domain of peptidase_M16 Adaptin_N PF01602.20 CRK19676.1 - 0.13 10.8 0.0 0.3 9.6 0.0 1.7 1 1 0 1 1 1 0 Adaptin N terminal region TFCD_C PF12612.8 CRK19676.1 - 0.15 11.9 0.2 14 5.4 0.0 3.4 3 1 0 3 3 3 0 Tubulin folding cofactor D C terminal FAD_binding_1 PF00667.20 CRK19686.1 - 2.3e-18 66.6 0.0 2.7e-18 66.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain ATG7_N PF16420.5 CRK19699.1 - 9.8e-25 87.8 0.0 1.3e-24 87.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus DUF3405 PF11885.8 CRK19699.1 - 4.1e-10 38.9 0.1 1.6e-09 37.0 0.0 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF3405) TRAM_LAG1_CLN8 PF03798.16 CRK19705.1 - 5.1e-51 173.2 13.1 6e-51 173.0 13.1 1.1 1 0 0 1 1 1 1 TLC domain A_deaminase PF00962.22 CRK19706.1 - 5.5e-122 407.2 0.1 7.7e-122 406.7 0.1 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase SHD1 PF03983.12 CRK19706.1 - 1.3e-24 85.8 0.1 3.8e-24 84.3 0.1 1.8 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 DUF1720 PF08226.11 CRK19706.1 - 1e-10 41.9 50.9 2.1e-09 37.7 27.2 4.1 2 1 2 4 4 4 2 Domain of unknown function (DUF1720) WD40 PF00400.32 CRK19706.1 - 4.7e-09 36.7 3.7 0.92 10.5 0.2 6.5 6 0 0 6 6 6 2 WD domain, G-beta repeat UAA PF08449.11 CRK19706.1 - 0.0001 21.7 0.0 0.00015 21.1 0.0 1.2 1 0 0 1 1 1 1 UAA transporter family SAM_4 PF18017.1 CRK19706.1 - 0.00021 21.2 0.0 0.00076 19.4 0.0 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) MutS_V PF00488.21 CRK19707.1 - 1e-45 156.1 0.0 1.6e-45 155.5 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 CRK19707.1 - 2.2e-16 60.7 0.0 8.3e-16 58.8 0.0 2.0 2 1 0 2 2 2 1 MutS domain III Ion_trans PF00520.31 CRK19708.1 - 1e-121 404.8 82.4 3.5e-44 150.9 5.5 4.7 4 1 0 4 4 4 4 Ion transport protein JSRP PF15312.6 CRK19708.1 - 0.024 14.5 0.1 0.08 12.9 0.1 1.9 1 0 0 1 1 1 0 Junctional sarcoplasmic reticulum protein Ribosomal_L2_C PF03947.18 CRK19709.1 - 1.8e-50 170.4 3.3 5e-50 168.9 3.3 1.8 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 CRK19709.1 - 2.6e-24 85.0 2.6 2.8e-24 84.9 1.2 1.8 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain Cyclin_N PF00134.23 CRK19710.1 - 3.4e-43 146.4 0.2 2.3e-42 143.7 0.0 2.5 4 0 0 4 4 4 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CRK19710.1 - 3.5e-32 111.0 0.0 7.2e-32 110.0 0.0 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain PAP2 PF01569.21 CRK19710.1 - 1.5e-21 76.6 0.3 5.4e-21 74.8 0.3 2.0 1 1 0 1 1 1 1 PAP2 superfamily DUF2142 PF09913.9 CRK19710.1 - 0.21 10.4 3.4 3.6 6.4 0.3 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2142) CK_II_beta PF01214.18 CRK19711.1 - 5.5e-73 244.7 0.2 6.9e-73 244.3 0.2 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit RIC1 PF07064.13 CRK19712.1 - 2.8e-144 479.1 2.1 1.7e-75 253.7 0.1 2.1 2 0 0 2 2 2 2 RIC1 TMEM206 PF15122.6 CRK19712.1 - 0.0096 15.1 0.1 4.5 6.3 0.0 2.3 2 0 0 2 2 2 2 TMEM206 protein family N_NLPC_P60 PF12912.7 CRK19712.1 - 0.034 14.5 0.1 10 6.5 0.0 2.4 2 0 0 2 2 2 0 NLPC_P60 stabilising domain, N term YLP PF02757.17 CRK19712.1 - 1.5 9.0 8.0 17 5.8 1.0 3.1 2 0 0 2 2 2 0 YLP motif WD40 PF00400.32 CRK19713.1 - 2.4e-10 40.8 0.7 0.066 14.1 0.0 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK19713.1 - 4.5e-05 23.7 0.0 0.79 10.1 0.0 3.1 2 2 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 CRK19713.1 - 0.18 10.3 0.0 0.95 7.9 0.0 1.9 2 0 0 2 2 2 0 Cytochrome D1 heme domain Nop PF01798.18 CRK19714.1 - 2.5e-70 236.5 0.4 5.5e-70 235.4 0.0 1.6 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 CRK19714.1 - 2.7e-45 154.2 2.4 6.4e-45 153.0 2.4 1.7 1 0 0 1 1 1 1 Prp31 C terminal domain RRN3 PF05327.11 CRK19714.1 - 0.11 11.0 4.0 0.16 10.4 4.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TPR_14 PF13428.6 CRK19715.1 - 1.1e-28 97.4 21.0 0.0004 21.0 0.1 10.9 8 4 3 11 11 10 6 Tetratricopeptide repeat HAT PF02184.16 CRK19715.1 - 2.1e-27 94.7 70.8 3.2e-14 52.6 3.4 12.7 15 0 0 15 15 14 5 HAT (Half-A-TPR) repeat TPR_19 PF14559.6 CRK19715.1 - 3.9e-19 68.9 5.8 4.2e-06 27.2 0.0 7.1 8 0 0 8 8 7 3 Tetratricopeptide repeat Suf PF05843.14 CRK19715.1 - 7.3e-17 62.3 19.5 0.00015 21.9 0.0 6.6 2 1 4 7 7 7 6 Suppressor of forked protein (Suf) TPR_17 PF13431.6 CRK19715.1 - 7.2e-11 41.7 0.2 0.068 13.6 0.0 6.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_15 PF13429.6 CRK19715.1 - 3.5e-09 36.3 13.7 0.017 14.4 2.2 6.0 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_6 PF13174.6 CRK19715.1 - 1.3e-08 34.9 18.8 0.84 10.4 0.2 9.2 10 0 0 10 10 9 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CRK19715.1 - 8.4e-08 32.2 7.2 2.2 8.4 0.0 6.6 6 1 0 6 6 6 2 Fis1 C-terminal tetratricopeptide repeat TPR_16 PF13432.6 CRK19715.1 - 9.5e-07 29.4 15.1 2.2 9.0 0.3 8.4 9 1 1 10 10 10 1 Tetratricopeptide repeat TPR_2 PF07719.17 CRK19715.1 - 1.4e-06 28.0 20.0 0.86 9.9 0.7 9.0 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_8 PF13181.6 CRK19715.1 - 2.3e-06 27.3 1.3 1.6 9.2 0.0 6.7 8 0 0 8 8 5 1 Tetratricopeptide repeat U3_assoc_6 PF08640.11 CRK19715.1 - 4.4e-05 23.5 20.2 0.0073 16.3 0.7 6.9 5 3 2 7 7 7 2 U3 small nucleolar RNA-associated protein 6 TPR_9 PF13371.6 CRK19715.1 - 0.00047 20.2 7.4 0.28 11.3 0.4 5.4 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 CRK19715.1 - 0.0012 18.8 4.9 0.18 11.9 0.2 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat NRDE-2 PF08424.10 CRK19715.1 - 0.0047 16.1 22.7 0.35 9.9 1.6 5.4 3 3 1 4 4 4 3 NRDE-2, necessary for RNA interference BSD PF03909.17 CRK19715.1 - 0.034 14.2 0.2 0.17 11.9 0.2 2.2 1 0 0 1 1 1 0 BSD domain TPR_1 PF00515.28 CRK19715.1 - 0.034 14.0 0.2 66 3.6 0.6 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 CRK19715.1 - 0.099 12.3 0.1 43 3.9 0.3 3.6 3 0 0 3 3 3 0 TPR repeat TPR_12 PF13424.6 CRK19715.1 - 4.4 7.7 18.4 13 6.1 0.2 6.6 9 1 0 9 9 8 0 Tetratricopeptide repeat La PF05383.17 CRK19716.1 - 8.8e-15 54.5 0.0 1.5e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 La domain NPR3 PF03666.13 CRK19717.1 - 3.3e-22 78.9 0.0 4.4e-22 78.5 0.0 1.1 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 WD40 PF00400.32 CRK19717.1 - 0.83 10.6 2.9 49 5.0 0.6 4.2 4 0 0 4 4 4 0 WD domain, G-beta repeat WD40 PF00400.32 CRK19718.1 - 5.4e-16 58.7 8.4 0.0001 23.0 1.6 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat Zn_clus PF00172.18 CRK19718.1 - 6.4e-09 35.8 8.7 1.2e-08 34.9 8.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ANAPC4_WD40 PF12894.7 CRK19718.1 - 1.6e-06 28.3 0.0 1.1 9.6 0.0 4.2 2 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain GST_N_3 PF13417.6 CRK19719.1 - 7e-18 64.8 0.0 1.4e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CRK19719.1 - 2.2e-15 56.7 0.0 4.9e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 CRK19719.1 - 8.2e-07 29.3 0.0 1.9e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CRK19719.1 - 2.4e-05 24.2 0.1 9e-05 22.4 0.1 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CRK19719.1 - 0.0017 18.5 0.1 0.011 16.0 0.0 2.3 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CRK19719.1 - 0.0022 18.2 0.0 0.0085 16.3 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 CRK19719.1 - 0.0069 16.6 0.1 0.017 15.3 0.1 1.6 1 0 0 1 1 1 1 Glutaredoxin FMN_red PF03358.15 CRK19719.1 - 0.069 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 NADPH-dependent FMN reductase GST_C_5 PF16865.5 CRK19719.1 - 0.15 12.7 0.0 0.27 11.8 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Integrin_B_tail PF07965.12 CRK19720.1 - 0.0081 16.6 0.1 0.012 16.0 0.1 1.3 1 0 0 1 1 1 1 Integrin beta tail domain zf-H2C2_2 PF13465.6 CRK19720.1 - 0.079 13.4 3.4 0.15 12.5 0.2 2.5 2 0 0 2 2 2 0 Zinc-finger double domain KAR9 PF08580.10 CRK19720.1 - 1.9 6.9 8.9 2.4 6.6 8.9 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 GST_N_3 PF13417.6 CRK19721.1 - 4e-17 62.4 0.0 7.6e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CRK19721.1 - 3.1e-15 56.2 0.0 5.5e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 CRK19721.1 - 4.1e-06 27.0 0.0 7.2e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CRK19721.1 - 2e-05 24.5 0.0 4.9e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CRK19721.1 - 3.9e-05 23.8 0.0 0.0002 21.5 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CRK19721.1 - 0.001 19.2 0.0 0.002 18.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 CRK19721.1 - 0.0036 17.5 0.1 0.0068 16.6 0.1 1.4 1 0 0 1 1 1 1 Glutaredoxin GST_C_5 PF16865.5 CRK19721.1 - 0.052 14.1 0.0 0.096 13.3 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Patched PF02460.18 CRK19721.1 - 0.37 8.8 0.3 0.51 8.3 0.3 1.1 1 0 0 1 1 1 0 Patched family zf-C2H2 PF00096.26 CRK19722.1 - 3.7e-05 23.9 9.8 0.0026 18.1 0.5 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CRK19722.1 - 0.0067 17.2 8.0 0.11 13.4 0.4 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CRK19722.1 - 0.01 16.2 0.7 0.01 16.2 0.7 2.6 3 0 0 3 3 3 0 Zinc-finger double domain Integrin_B_tail PF07965.12 CRK19722.1 - 0.015 15.8 0.5 0.035 14.6 0.2 1.7 1 1 1 2 2 2 0 Integrin beta tail domain zf-met PF12874.7 CRK19722.1 - 0.091 13.2 6.6 0.39 11.2 0.2 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Nop PF01798.18 CRK19723.1 - 2.6e-70 236.5 0.5 4.2e-70 235.8 0.0 1.6 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 CRK19723.1 - 6.3e-45 153.0 2.4 6.3e-45 153.0 2.4 1.8 2 0 0 2 2 2 1 Prp31 C terminal domain RRN3 PF05327.11 CRK19723.1 - 0.058 11.9 1.9 0.082 11.4 1.9 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TPR_14 PF13428.6 CRK19724.1 - 9.7e-29 97.6 20.7 0.0004 21.0 0.1 10.8 8 4 3 11 11 10 6 Tetratricopeptide repeat HAT PF02184.16 CRK19724.1 - 3.5e-27 94.1 71.4 3.2e-14 52.6 3.4 12.7 15 0 0 15 15 14 5 HAT (Half-A-TPR) repeat TPR_19 PF14559.6 CRK19724.1 - 1.8e-20 73.2 1.2 4.2e-06 27.2 0.0 6.9 7 0 0 7 7 6 3 Tetratricopeptide repeat Suf PF05843.14 CRK19724.1 - 1.3e-16 61.4 20.1 0.00015 21.9 0.1 6.6 2 1 3 6 6 6 5 Suppressor of forked protein (Suf) TPR_17 PF13431.6 CRK19724.1 - 8.3e-11 41.5 0.2 0.068 13.6 0.0 6.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_15 PF13429.6 CRK19724.1 - 7.8e-09 35.1 13.8 0.0069 15.6 1.8 5.8 3 2 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 CRK19724.1 - 1.6e-08 34.6 18.0 0.84 10.4 0.2 9.1 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_16 PF13432.6 CRK19724.1 - 7.9e-08 32.8 11.2 2.2 9.0 0.3 8.3 10 0 0 10 10 9 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CRK19724.1 - 9e-08 32.1 7.2 2.2 8.4 0.0 6.6 6 1 0 6 6 6 2 Fis1 C-terminal tetratricopeptide repeat TPR_2 PF07719.17 CRK19724.1 - 1.5e-06 27.9 20.0 0.86 9.9 0.7 9.0 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_8 PF13181.6 CRK19724.1 - 1.9e-06 27.6 1.0 1.6 9.2 0.0 6.7 8 0 0 8 8 5 1 Tetratricopeptide repeat U3_assoc_6 PF08640.11 CRK19724.1 - 5.1e-05 23.3 20.5 0.0073 16.3 0.7 6.9 5 3 2 7 7 7 2 U3 small nucleolar RNA-associated protein 6 TPR_9 PF13371.6 CRK19724.1 - 0.00046 20.3 7.4 0.28 11.3 0.4 5.4 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 CRK19724.1 - 0.0017 18.3 4.6 0.18 11.9 0.2 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat NRDE-2 PF08424.10 CRK19724.1 - 0.0034 16.6 22.1 0.35 9.9 1.6 5.3 3 3 0 3 3 3 3 NRDE-2, necessary for RNA interference BSD PF03909.17 CRK19724.1 - 0.034 14.1 0.3 0.16 12.0 0.3 2.2 1 0 0 1 1 1 0 BSD domain TPR_1 PF00515.28 CRK19724.1 - 0.036 13.9 0.2 66 3.6 0.6 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 CRK19724.1 - 0.1 12.3 0.1 43 3.9 0.3 3.6 3 0 0 3 3 3 0 TPR repeat TPR_12 PF13424.6 CRK19724.1 - 2.2 8.6 17.4 13 6.1 0.2 6.6 9 1 0 9 9 8 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 CRK19724.1 - 9.5 6.2 22.6 2.9 7.9 0.0 6.4 5 3 2 7 7 7 0 Mad3/BUB1 homology region 1 La PF05383.17 CRK19726.1 - 9e-15 54.5 0.0 1.5e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 La domain Peptidase_C14 PF00656.22 CRK19727.1 - 6.5e-61 206.4 0.0 8.1e-61 206.1 0.0 1.1 1 0 0 1 1 1 1 Caspase domain COesterase PF00135.28 CRK19728.1 - 3.7e-74 250.4 0.0 4.8e-74 250.1 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CRK19728.1 - 5.8e-13 49.2 0.1 1.5e-12 47.8 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CRK19728.1 - 0.016 14.7 0.1 0.029 13.9 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 CRK19728.1 - 0.22 10.3 0.1 0.4 9.5 0.1 1.4 1 1 0 1 1 1 0 Steryl acetyl hydrolase Methyltransf_25 PF13649.6 CRK19729.1 - 7.7e-11 42.6 0.1 2.2e-10 41.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 CRK19729.1 - 1.2e-10 41.3 0.0 1.8e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 CRK19729.1 - 1.1e-09 38.2 0.0 1.7e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CRK19729.1 - 2.6e-07 31.2 0.0 6.4e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CRK19729.1 - 7.4e-06 25.9 0.0 1.2e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 CRK19729.1 - 9.9e-06 24.7 0.3 1.8e-05 23.9 0.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) Methyltransf_18 PF12847.7 CRK19729.1 - 5.8e-05 23.1 0.1 9.6e-05 22.3 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CRK19729.1 - 0.0015 17.9 0.0 0.0021 17.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 CRK19729.1 - 0.0016 18.0 0.1 0.0026 17.4 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PRMT5 PF05185.16 CRK19729.1 - 0.0089 15.9 0.1 0.02 14.7 0.1 1.6 1 1 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_12 PF08242.12 CRK19729.1 - 0.0096 16.6 0.0 0.017 15.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PRMT5_C PF17286.2 CRK19729.1 - 0.011 15.6 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 PRMT5 oligomerisation domain Methyltransf_32 PF13679.6 CRK19729.1 - 0.02 14.9 0.0 0.035 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 CRK19729.1 - 0.044 13.5 0.2 0.067 12.9 0.2 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 CRK19729.1 - 0.049 13.4 0.0 0.074 12.8 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_24 PF13578.6 CRK19729.1 - 0.057 14.5 0.0 0.14 13.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain zf-RING_2 PF13639.6 CRK19730.1 - 7.4e-11 42.2 3.2 1.3e-10 41.4 3.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 CRK19730.1 - 2.3e-09 37.4 2.2 5e-09 36.3 2.2 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CRK19730.1 - 3.3e-07 30.3 0.4 6.5e-07 29.3 0.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 CRK19730.1 - 8.1e-06 25.6 5.9 2.3e-05 24.2 5.9 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CRK19730.1 - 1.1e-05 25.2 2.0 1.9e-05 24.5 2.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CRK19730.1 - 5.3e-05 23.2 0.9 0.0001 22.3 0.4 1.8 1 1 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 CRK19730.1 - 9.6e-05 22.2 2.2 0.00018 21.3 2.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 CRK19730.1 - 0.00013 21.7 2.6 0.00023 20.9 2.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CRK19730.1 - 0.00019 21.2 2.5 0.00039 20.2 2.5 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 CRK19730.1 - 0.0054 16.9 4.0 0.17 12.1 4.0 2.5 1 1 0 1 1 1 1 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 CRK19730.1 - 0.0068 16.0 0.6 0.0068 16.0 0.6 1.6 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 CRK19730.1 - 0.015 15.0 0.5 0.046 13.5 0.5 1.9 1 1 0 1 1 1 0 RING-like zinc finger zf-Nse PF11789.8 CRK19730.1 - 0.1 12.5 0.4 0.21 11.4 0.4 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Rtf2 PF04641.12 CRK19730.1 - 0.1 11.9 0.6 0.23 10.8 0.3 1.7 2 1 0 2 2 2 0 Rtf2 RING-finger zf-C3HC4_4 PF15227.6 CRK19730.1 - 1.1 9.5 3.3 0.45 10.7 0.4 1.8 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Cullin PF00888.22 CRK19731.1 - 2.2e-22 79.5 1.6 4e-22 78.6 1.6 1.3 1 0 0 1 1 1 1 Cullin family ANAPC2 PF08672.11 CRK19731.1 - 2.7e-21 75.8 0.0 2e-20 73.0 0.2 2.6 3 0 0 3 3 3 1 Anaphase promoting complex (APC) subunit 2 CAP_N PF01213.19 CRK19731.1 - 0.0024 17.4 0.3 0.0024 17.4 0.3 2.4 2 0 0 2 2 2 1 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 CRK19731.1 - 0.24 11.5 4.2 0.62 10.1 4.2 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 zf-C2H2 PF00096.26 CRK19732.1 - 0.0067 16.8 3.7 0.37 11.3 0.4 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CRK19732.1 - 0.045 14.6 2.2 9.7 7.3 0.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-ribbon_3 PF13248.6 CRK19732.1 - 0.08 12.4 0.1 0.14 11.6 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain MFS_2 PF13347.6 CRK19733.1 - 1.5e-09 37.0 13.7 2.9e-09 36.0 13.7 1.4 1 0 0 1 1 1 1 MFS/sugar transport protein CbiJ PF02571.14 CRK19733.1 - 0.001 18.6 0.0 1.7 8.0 0.0 2.3 2 0 0 2 2 2 2 Precorrin-6x reductase CbiJ/CobK MFS_1_like PF12832.7 CRK19733.1 - 0.0018 17.2 1.1 0.0032 16.4 1.1 1.3 1 0 0 1 1 1 1 MFS_1 like family FAST_1 PF06743.15 CRK19733.1 - 0.0022 17.9 0.2 3.6 7.6 0.0 2.5 2 0 0 2 2 2 2 FAST kinase-like protein, subdomain 1 MbeB_N PF04837.12 CRK19733.1 - 0.01 16.1 0.0 9.3 6.6 0.0 2.5 2 0 0 2 2 2 0 MbeB-like, N-term conserved region PUCC PF03209.15 CRK19733.1 - 0.011 14.8 6.1 0.017 14.1 6.1 1.2 1 0 0 1 1 1 0 PUCC protein NTP_transf_6 PF06042.11 CRK19733.1 - 0.16 11.8 0.0 0.99 9.2 0.0 2.3 3 0 0 3 3 3 0 Nucleotidyltransferase EF_assoc_2 PF08356.12 CRK19733.1 - 0.17 11.9 1.5 22 5.1 0.1 2.5 2 0 0 2 2 2 0 EF hand associated CTD_bind PF04818.13 CRK19733.1 - 0.19 12.6 0.1 66 4.4 0.0 3.2 2 0 0 2 2 2 0 RNA polymerase II-binding domain. HisG PF01634.18 CRK19734.1 - 3.3e-42 144.2 0.0 4.7e-42 143.7 0.0 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 CRK19734.1 - 1.5e-27 95.5 0.2 3.2e-27 94.5 0.2 1.6 1 0 0 1 1 1 1 HisG, C-terminal domain Zn_clus PF00172.18 CRK19736.1 - 4.7e-06 26.6 6.9 7.1e-06 26.0 6.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF202 PF02656.15 CRK19737.1 - 0.00029 21.2 4.3 0.00029 21.2 4.3 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF202) DUF202 PF02656.15 CRK19738.1 - 0.00029 21.2 4.3 0.00029 21.2 4.3 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF202) zf-C2H2 PF00096.26 CRK19739.1 - 8.9e-07 29.0 21.1 0.00081 19.7 0.5 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CRK19739.1 - 0.0025 18.5 0.8 0.0025 18.5 0.8 4.5 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CRK19739.1 - 0.025 14.6 0.4 0.025 14.6 0.4 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger FOXP-CC PF16159.5 CRK19739.1 - 6.3 7.5 9.9 5.3 7.8 2.0 2.8 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_2 PF12756.7 CRK19739.1 - 7.2 7.0 7.8 0.92 9.9 2.2 2.3 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) TRP_N PF14558.6 CRK19740.1 - 2.7e-19 69.9 0.5 4.7e-19 69.1 0.5 1.3 1 0 0 1 1 1 1 ML-like domain zf-C2H2 PF00096.26 CRK19740.1 - 4.4e-08 33.1 21.1 0.00039 20.7 0.5 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CRK19740.1 - 0.0012 19.5 0.8 0.0012 19.5 0.8 4.8 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CRK19740.1 - 0.012 15.6 0.4 0.012 15.6 0.4 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger Beta_helix_2 PF18835.1 CRK19740.1 - 0.051 13.3 0.6 0.1 12.4 0.6 1.4 1 0 0 1 1 1 0 Beta helix repeat of Inulin fructotransferase Wza_C PF18412.1 CRK19740.1 - 0.15 11.8 0.1 0.32 10.8 0.1 1.5 1 0 0 1 1 1 0 Outer-membrane lipoprotein Wza C-terminal domain YdjO PF14169.6 CRK19740.1 - 4.2 7.2 7.6 0.94 9.3 1.9 2.5 2 0 0 2 2 2 0 Cold-inducible protein YdjO zf-C2H2_jaz PF12171.8 CRK19740.1 - 5.5 7.4 9.4 24 5.4 0.1 3.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 CRK19740.1 - 8.5 6.8 10.0 0.26 11.6 1.5 2.6 3 1 0 3 3 3 0 C2H2 type zinc-finger (2 copies) Abhydrolase_6 PF12697.7 CRK19741.1 - 2e-20 74.3 17.7 2e-20 74.3 17.7 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CRK19741.1 - 3.6e-08 33.0 0.1 5.4e-08 32.4 0.1 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CRK19741.1 - 3e-06 27.1 0.0 7.6e-06 25.7 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 CRK19741.1 - 0.0053 16.9 0.1 0.011 15.8 0.1 1.5 1 0 0 1 1 1 1 Thioesterase domain DNA_pol_B_palm PF14792.6 CRK19742.1 - 7.7e-35 119.5 0.0 1.3e-34 118.8 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 CRK19742.1 - 1.9e-23 82.4 0.3 4e-23 81.3 0.3 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 CRK19742.1 - 2.6e-19 68.8 0.1 6.8e-19 67.4 0.1 1.8 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 CRK19742.1 - 1.9e-15 57.0 0.3 4.8e-15 55.7 0.3 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_5 PF14520.6 CRK19742.1 - 0.0098 16.5 0.0 0.032 14.8 0.0 1.9 1 1 0 1 1 1 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.23 CRK19742.1 - 0.016 15.5 0.0 0.036 14.4 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase domain Ammonium_transp PF00909.21 CRK19743.1 - 2.8e-117 391.8 26.6 3.2e-117 391.6 26.6 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Abhydrolase_6 PF12697.7 CRK19744.1 - 7.7e-18 65.9 15.4 1.1e-17 65.4 15.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CRK19744.1 - 3.7e-07 29.7 0.0 5.3e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CRK19744.1 - 2.3e-05 24.2 0.0 4.6e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold DNA_pol_B_palm PF14792.6 CRK19745.1 - 4.8e-35 120.2 0.0 7.8e-35 119.5 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 CRK19745.1 - 1.4e-23 82.8 0.4 3.2e-23 81.7 0.4 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 CRK19745.1 - 1.4e-19 69.6 0.2 3.8e-19 68.3 0.2 1.8 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 CRK19745.1 - 2.4e-15 56.6 0.2 6.1e-15 55.3 0.2 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.23 CRK19745.1 - 0.0017 18.6 0.0 0.0034 17.6 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain HHH_5 PF14520.6 CRK19745.1 - 0.011 16.3 0.0 0.032 14.8 0.0 1.8 1 1 0 1 1 1 0 Helix-hairpin-helix domain PELOTA_1 PF15608.6 CRK19747.1 - 0.0042 16.9 0.9 0.0088 15.9 0.9 1.5 1 0 0 1 1 1 1 PELOTA RNA binding domain Ammonium_transp PF00909.21 CRK19748.1 - 1.1e-116 389.9 26.6 1.2e-116 389.7 26.6 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Med16 PF11635.8 CRK19749.1 - 6.8e-58 196.3 0.0 8e-32 110.0 0.0 3.0 1 1 1 2 2 2 2 Mediator complex subunit 16 Ribul_P_3_epim PF00834.19 CRK19750.1 - 1.2e-60 204.3 0.0 3.7e-60 202.7 0.0 1.8 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family SIR2 PF02146.17 CRK19750.1 - 2.5e-26 92.7 0.0 6.3e-26 91.4 0.0 1.7 1 1 0 1 1 1 1 Sir2 family ThiG PF05690.14 CRK19750.1 - 0.036 13.4 0.0 0.071 12.4 0.0 1.4 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG MAP65_ASE1 PF03999.12 CRK19750.1 - 9.4 4.8 13.5 17 3.9 13.5 1.3 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Med16 PF11635.8 CRK19751.1 - 1.6e-64 218.2 0.0 7.3e-39 133.3 0.0 2.2 1 1 1 2 2 2 2 Mediator complex subunit 16 SNF2_N PF00176.23 CRK19751.1 - 6.7e-54 182.9 0.2 1.3e-53 182.0 0.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 CRK19751.1 - 6.9e-24 83.5 7.7 1.9e-15 56.5 0.9 3.5 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 CRK19751.1 - 8.6e-20 71.1 0.0 2.3e-19 69.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4208 PF13907.6 CRK19751.1 - 1.6e-13 50.9 0.0 5.3e-13 49.2 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) HDA2-3 PF11496.8 CRK19751.1 - 1e-07 31.4 0.0 3.3e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 CRK19751.1 - 6e-07 29.6 0.0 2.9e-06 27.4 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CDH1_2_SANT_HL1 PF18375.1 CRK19751.1 - 0.0052 17.4 0.5 0.0052 17.4 0.5 2.8 2 0 0 2 2 1 1 CDH1/2 SANT-Helical linker 1 Cdh1_DBD_1 PF18196.1 CRK19751.1 - 0.009 16.3 0.2 0.009 16.3 0.2 4.8 4 1 1 5 5 4 2 Chromodomain helicase DNA-binding domain 1 AAA_22 PF13401.6 CRK19751.1 - 0.016 15.5 0.0 0.074 13.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain SLIDE PF09111.10 CRK19751.1 - 0.028 14.5 0.9 0.18 11.8 0.0 2.7 2 0 0 2 2 2 0 SLIDE CHDCT2 PF08074.11 CRK19751.1 - 4 7.6 6.2 2.5 8.3 0.0 3.4 4 0 0 4 4 4 0 CHDCT2 (NUC038) domain Ribul_P_3_epim PF00834.19 CRK19752.1 - 2.3e-62 209.9 0.0 1.4e-61 207.4 0.0 1.9 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family ThiG PF05690.14 CRK19752.1 - 0.012 14.9 0.1 0.019 14.3 0.1 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG OMPdecase PF00215.24 CRK19752.1 - 0.028 14.0 0.0 0.052 13.1 0.0 1.5 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family SIR2 PF02146.17 CRK19753.1 - 8.2e-24 84.5 0.0 2.4e-23 83.0 0.0 1.7 1 1 0 1 1 1 1 Sir2 family Helicase_C PF00271.31 CRK19754.1 - 2.9e-20 72.7 0.0 7e-20 71.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4208 PF13907.6 CRK19754.1 - 4.2e-14 52.7 0.0 1.6e-13 50.8 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) SNF2_N PF00176.23 CRK19754.1 - 8.6e-14 51.0 0.1 1.5e-13 50.2 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HDA2-3 PF11496.8 CRK19754.1 - 8.3e-08 31.7 0.0 8.3e-08 31.7 0.0 2.2 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 CDH1_2_SANT_HL1 PF18375.1 CRK19754.1 - 0.0023 18.6 0.5 0.0023 18.6 0.5 3.2 2 0 0 2 2 2 1 CDH1/2 SANT-Helical linker 1 Cdh1_DBD_1 PF18196.1 CRK19754.1 - 0.0034 17.7 0.2 0.0034 17.7 0.2 4.9 4 1 1 5 5 5 2 Chromodomain helicase DNA-binding domain 1 SLIDE PF09111.10 CRK19754.1 - 0.004 17.1 1.5 0.057 13.5 0.1 3.1 2 0 0 2 2 2 1 SLIDE CHDCT2 PF08074.11 CRK19754.1 - 0.88 9.7 0.0 0.88 9.7 0.0 3.2 4 0 0 4 4 4 0 CHDCT2 (NUC038) domain ABC_tran PF00005.27 CRK19755.1 - 3.7e-23 82.6 0.0 1.2e-14 55.0 0.0 2.3 2 0 0 2 2 2 2 ABC transporter RLI PF04068.15 CRK19755.1 - 6.9e-14 51.4 5.3 6.9e-14 51.4 5.3 2.0 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.6 CRK19755.1 - 7e-09 35.9 1.4 0.12 12.2 1.3 3.3 2 1 1 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 CRK19755.1 - 8.1e-06 25.8 0.2 0.12 12.0 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain Fer4 PF00037.27 CRK19755.1 - 1.2e-05 24.9 1.8 1.2e-05 24.9 1.8 2.9 3 0 0 3 3 3 1 4Fe-4S binding domain AAA PF00004.29 CRK19755.1 - 1.2e-05 25.7 0.1 0.012 16.1 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CRK19755.1 - 1.7e-05 25.1 0.0 0.0042 17.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CRK19755.1 - 2.6e-05 24.7 0.0 0.18 12.2 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 CRK19755.1 - 7.9e-05 23.2 0.5 0.015 15.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain Fer4_10 PF13237.6 CRK19755.1 - 0.00013 22.0 8.3 0.0083 16.2 0.1 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain RsgA_GTPase PF03193.16 CRK19755.1 - 0.00014 21.8 0.1 0.43 10.5 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Rad17 PF03215.15 CRK19755.1 - 0.00017 21.6 0.2 0.028 14.3 0.1 2.5 2 1 0 2 2 2 1 Rad17 P-loop domain AAA_18 PF13238.6 CRK19755.1 - 0.00019 22.0 0.1 1.1 9.8 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.6 CRK19755.1 - 0.00022 20.9 0.3 0.35 10.7 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain RNA_helicase PF00910.22 CRK19755.1 - 0.00041 20.7 0.6 0.2 12.1 0.0 2.6 3 0 0 3 3 2 1 RNA helicase AAA_24 PF13479.6 CRK19755.1 - 0.00043 20.0 0.1 0.13 12.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 CRK19755.1 - 0.00063 19.4 2.0 0.053 13.2 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain NACHT PF05729.12 CRK19755.1 - 0.00072 19.5 0.4 0.18 11.7 0.0 2.5 3 0 0 3 3 2 1 NACHT domain Fer4_21 PF14697.6 CRK19755.1 - 0.001 19.2 10.2 0.0019 18.3 10.2 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 CRK19755.1 - 0.0015 18.5 11.6 0.0042 17.1 1.2 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_33 PF13671.6 CRK19755.1 - 0.0021 18.2 0.0 0.3 11.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 CRK19755.1 - 0.0023 17.9 0.0 0.034 14.2 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 CRK19755.1 - 0.003 17.1 0.2 0.07 12.6 0.1 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_13 PF13166.6 CRK19755.1 - 0.0034 16.1 0.7 0.0047 15.7 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 CRK19755.1 - 0.0035 17.4 0.2 0.22 11.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Fer4_7 PF12838.7 CRK19755.1 - 0.0045 17.5 7.4 0.0071 16.9 0.3 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain Thymidylate_kin PF02223.17 CRK19755.1 - 0.0052 16.5 0.0 1.5 8.5 0.0 2.2 2 0 0 2 2 2 1 Thymidylate kinase SMC_N PF02463.19 CRK19755.1 - 0.006 16.0 0.8 4 6.8 0.2 3.1 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 CRK19755.1 - 0.0089 16.3 0.3 1.3 9.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain Fer4_9 PF13187.6 CRK19755.1 - 0.015 15.5 10.0 0.032 14.4 10.0 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain NB-ARC PF00931.22 CRK19755.1 - 0.017 14.3 0.0 1.4 8.1 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain Fer4_16 PF13484.6 CRK19755.1 - 0.041 14.8 0.2 0.041 14.8 0.2 2.7 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain AAA_30 PF13604.6 CRK19755.1 - 0.042 13.6 0.2 2.7 7.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain VirE PF05272.11 CRK19755.1 - 0.076 12.7 0.0 5.2 6.7 0.0 2.3 2 0 0 2 2 2 0 Virulence-associated protein E TniB PF05621.11 CRK19755.1 - 0.085 12.3 0.0 0.58 9.5 0.0 2.0 2 0 0 2 2 2 0 Bacterial TniB protein MMR_HSR1 PF01926.23 CRK19755.1 - 0.13 12.4 0.9 19 5.4 0.3 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_14 PF13173.6 CRK19755.1 - 0.15 12.1 0.4 13 5.9 0.0 2.6 2 1 0 2 2 2 0 AAA domain Fer4_8 PF13183.6 CRK19755.1 - 0.16 12.5 6.7 0.19 12.2 0.2 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain ATPase PF06745.13 CRK19755.1 - 0.19 11.0 0.0 0.42 9.9 0.0 1.5 1 0 0 1 1 1 0 KaiC RuvB_N PF05496.12 CRK19755.1 - 0.2 11.4 0.1 4.6 7.0 0.0 2.6 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain NTPase_1 PF03266.15 CRK19755.1 - 0.26 11.2 2.3 4.9 7.0 0.1 2.4 2 0 0 2 2 2 0 NTPase PduV-EutP PF10662.9 CRK19755.1 - 0.38 10.5 1.9 0.46 10.2 0.1 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation CLP1_P PF16575.5 CRK19755.1 - 0.5 10.1 2.1 1.1 9.0 0.1 2.1 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Fer4_2 PF12797.7 CRK19755.1 - 1.8 8.8 10.1 0.35 11.1 1.1 2.7 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_17 PF13534.6 CRK19755.1 - 9.5 6.8 11.7 0.2 12.2 1.1 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Peptidase_C53 PF05550.11 CRK19756.1 - 0.18 11.4 0.1 0.25 11.0 0.1 1.2 1 0 0 1 1 1 0 Pestivirus Npro endopeptidase C53 PRCC PF10253.9 CRK19756.1 - 0.86 10.3 7.9 1.1 10.0 7.9 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting ABC_tran PF00005.27 CRK19757.1 - 1e-38 132.9 0.0 3.8e-14 53.4 0.0 3.6 3 0 0 3 3 3 3 ABC transporter SMC_N PF02463.19 CRK19757.1 - 1.6e-15 57.1 0.9 0.00039 19.9 0.0 4.5 3 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain RLI PF04068.15 CRK19757.1 - 1.5e-13 50.3 5.3 1.5e-13 50.3 5.3 1.9 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.6 CRK19757.1 - 2.5e-12 47.2 5.1 0.24 11.2 1.2 5.5 3 2 1 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 CRK19757.1 - 1.4e-05 25.0 0.7 0.28 10.8 0.0 3.3 4 1 1 5 5 4 2 AAA ATPase domain Fer4 PF00037.27 CRK19757.1 - 2.5e-05 23.9 1.8 2.5e-05 23.9 1.8 2.5 3 0 0 3 3 3 1 4Fe-4S binding domain AAA_16 PF13191.6 CRK19757.1 - 2.9e-05 24.5 0.0 0.11 12.8 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 CRK19757.1 - 3.1e-05 24.3 0.0 0.0044 17.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 CRK19757.1 - 5e-05 23.7 0.1 0.027 14.9 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 CRK19757.1 - 0.00047 20.1 0.1 1.6 8.6 0.0 3.0 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 CRK19757.1 - 0.00048 20.7 0.5 0.051 14.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain Fer4_10 PF13237.6 CRK19757.1 - 0.00059 19.9 8.3 0.018 15.1 0.1 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain AAA_18 PF13238.6 CRK19757.1 - 0.00065 20.2 0.0 2.1 8.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 CRK19757.1 - 0.00099 18.8 0.2 0.77 9.6 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain Rad17 PF03215.15 CRK19757.1 - 0.001 19.0 0.0 0.059 13.3 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain RNA_helicase PF00910.22 CRK19757.1 - 0.001 19.4 0.1 0.35 11.3 0.0 2.7 2 0 0 2 2 2 1 RNA helicase SRP54 PF00448.22 CRK19757.1 - 0.0017 18.0 1.4 0.11 12.1 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_21 PF14697.6 CRK19757.1 - 0.0021 18.2 10.2 0.0045 17.1 10.2 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_24 PF13479.6 CRK19757.1 - 0.0027 17.4 0.1 0.41 10.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_13 PF13166.6 CRK19757.1 - 0.0043 15.8 0.2 0.016 13.8 0.0 2.0 2 0 0 2 2 1 1 AAA domain NACHT PF05729.12 CRK19757.1 - 0.0052 16.7 0.5 0.62 10.0 0.0 2.6 2 0 0 2 2 2 1 NACHT domain Nucleotid_trans PF03407.16 CRK19757.1 - 0.0062 16.5 0.0 5.9 6.8 0.0 2.7 3 0 0 3 3 3 0 Nucleotide-diphospho-sugar transferase Fer4_6 PF12837.7 CRK19757.1 - 0.0067 16.5 11.6 0.0088 16.1 1.2 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_33 PF13671.6 CRK19757.1 - 0.0073 16.5 0.0 0.86 9.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 CRK19757.1 - 0.01 15.8 0.1 0.078 13.0 0.0 2.2 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Thymidylate_kin PF02223.17 CRK19757.1 - 0.01 15.5 0.3 3.4 7.3 0.0 3.0 3 0 0 3 3 3 0 Thymidylate kinase AAA_5 PF07728.14 CRK19757.1 - 0.012 15.6 0.1 0.49 10.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 CRK19757.1 - 0.014 14.9 0.4 0.18 11.3 0.1 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region Fer4_7 PF12838.7 CRK19757.1 - 0.016 15.8 0.4 0.016 15.8 0.4 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain SbcCD_C PF13558.6 CRK19757.1 - 0.031 14.5 0.0 20 5.5 0.0 3.6 3 1 0 3 3 3 0 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.6 CRK19757.1 - 0.045 14.0 0.3 3.8 7.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 CRK19757.1 - 0.046 12.9 0.0 3.4 6.8 0.0 2.6 3 0 0 3 3 3 0 NB-ARC domain Fer4_9 PF13187.6 CRK19757.1 - 0.056 13.6 10.6 0.11 12.6 10.6 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_16 PF13484.6 CRK19757.1 - 0.092 13.7 0.3 0.092 13.7 0.3 2.7 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain AAA_30 PF13604.6 CRK19757.1 - 0.12 12.1 0.1 5.4 6.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 CRK19757.1 - 0.2 11.8 0.4 31 4.7 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase PduV-EutP PF10662.9 CRK19757.1 - 0.52 10.1 3.3 0.97 9.2 0.0 2.8 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.15 CRK19757.1 - 0.55 10.1 1.9 9.5 6.1 0.0 2.7 2 0 0 2 2 2 0 NTPase Fer4_2 PF12797.7 CRK19757.1 - 8.9 6.6 10.2 0.73 10.1 1.1 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_8 PF13183.6 CRK19757.1 - 9.3 6.8 10.5 1.2 9.7 1.5 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain FF PF01846.19 CRK19758.1 - 1.6e-50 169.1 15.2 4.8e-14 52.3 0.0 8.3 7 1 0 7 7 7 7 FF domain WW PF00397.26 CRK19758.1 - 1.8e-18 66.3 16.4 1.6e-10 40.9 2.4 2.8 2 0 0 2 2 2 2 WW domain Glyco_hyd_101C PF17451.2 CRK19758.1 - 0.049 13.9 9.1 0.31 11.4 0.5 2.8 1 1 1 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain Lipin_mid PF16876.5 CRK19758.1 - 0.21 11.7 0.6 5.6 7.2 0.4 2.7 1 1 1 2 2 2 0 Lipin/Ned1/Smp2 multi-domain protein middle domain Trs65 PF12735.7 CRK19759.1 - 2.4e-123 411.6 0.0 4e-123 410.9 0.0 1.3 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 PelD_GGDEF PF16963.5 CRK19759.1 - 0.1 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 PelD GGDEF domain SLD3 PF08639.10 CRK19760.1 - 1.2e-176 588.7 8.2 1.2e-176 588.7 8.2 1.9 2 0 0 2 2 2 1 DNA replication regulator SLD3 WW PF00397.26 CRK19760.1 - 1.8e-18 66.3 16.4 1.4e-10 41.0 2.4 2.5 2 0 0 2 2 2 2 WW domain Glyco_hyd_101C PF17451.2 CRK19760.1 - 0.046 14.0 9.4 0.18 12.1 0.6 2.7 1 1 1 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain Trs65 PF12735.7 CRK19761.1 - 8e-126 419.7 0.0 1.4e-125 419.0 0.0 1.4 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 PelD_GGDEF PF16963.5 CRK19761.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 PelD GGDEF domain SLD3 PF08639.10 CRK19762.1 - 7.7e-178 592.6 9.2 7.7e-178 592.6 9.2 2.0 2 0 0 2 2 2 1 DNA replication regulator SLD3 CBFD_NFYB_HMF PF00808.23 CRK19763.1 - 6.1e-07 29.6 0.0 1e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CRK19763.1 - 2.4e-05 24.7 0.0 9.3e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 CRK19763.1 - 0.056 13.6 0.0 0.11 12.7 0.0 1.4 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold PPP4R2 PF09184.11 CRK19763.1 - 0.34 10.5 12.0 0.59 9.7 12.0 1.5 1 0 0 1 1 1 0 PPP4R2 Nop14 PF04147.12 CRK19763.1 - 0.97 7.6 23.7 1.3 7.2 23.7 1.1 1 0 0 1 1 1 0 Nop14-like family RPN2_C PF18004.1 CRK19763.1 - 5 7.0 8.5 9.9 6.1 8.5 1.6 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain SAPS PF04499.15 CRK19763.1 - 7.2 5.3 6.7 8.6 5.0 6.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CRC_subunit PF08624.10 CRK19764.1 - 2.1e-51 173.9 0.0 3e-51 173.4 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit CBFD_NFYB_HMF PF00808.23 CRK19765.1 - 8e-08 32.5 0.0 1.5e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CRK19765.1 - 2.1e-05 24.9 0.1 6.4e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 CRK19765.1 - 0.016 15.3 0.0 0.031 14.4 0.0 1.4 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold Nop14 PF04147.12 CRK19765.1 - 0.34 9.1 18.2 0.39 8.9 18.2 1.1 1 0 0 1 1 1 0 Nop14-like family CRC_subunit PF08624.10 CRK19766.1 - 3.2e-51 173.3 0.0 4.7e-51 172.8 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit RNB PF00773.19 CRK19767.1 - 1.9e-95 320.0 0.2 2.6e-95 319.5 0.2 1.2 1 0 0 1 1 1 1 RNB domain Rrp44_S1 PF17215.3 CRK19767.1 - 6.6e-31 106.1 0.1 2.1e-30 104.5 0.1 1.9 1 0 0 1 1 1 1 S1 domain Rrp44_CSD1 PF17216.3 CRK19767.1 - 6.5e-30 103.8 0.1 1.9e-29 102.3 0.1 1.8 1 1 0 1 1 1 1 Rrp44-like cold shock domain OB_Dis3 PF17849.1 CRK19767.1 - 1.1e-19 70.2 0.0 2.9e-19 68.8 0.0 1.8 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 CRK19767.1 - 2.6e-09 37.4 0.0 7e-09 36.1 0.0 1.8 1 0 0 1 1 1 1 PIN domain CSD2 PF17876.1 CRK19767.1 - 4.9e-07 29.8 0.1 0.00091 19.3 0.0 3.0 3 0 0 3 3 3 2 Cold shock domain Dis3l2_C_term PF17877.1 CRK19767.1 - 0.041 14.2 0.0 0.13 12.6 0.0 1.9 1 0 0 1 1 1 0 DIS3-like exonuclease 2 C terminal TcfC PF16967.5 CRK19767.1 - 0.08 12.4 0.0 0.55 9.8 0.0 2.3 2 0 0 2 2 2 0 E-set like domain GN3L_Grn1 PF08701.11 CRK19768.1 - 2e-24 85.5 17.0 3.9e-24 84.5 17.0 1.5 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 CRK19768.1 - 1.3e-15 57.5 0.2 6.4e-13 48.8 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.23 CRK19768.1 - 0.00015 21.9 5.4 0.019 15.1 0.1 3.8 3 1 1 4 4 4 1 Dynamin family FeoB_N PF02421.18 CRK19768.1 - 0.00035 20.1 0.2 0.0015 18.1 0.1 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CRK19768.1 - 0.031 14.2 0.0 0.069 13.1 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AIG1 PF04548.16 CRK19768.1 - 0.065 12.6 0.0 0.18 11.1 0.0 1.7 2 0 0 2 2 2 0 AIG1 family MeaB PF03308.16 CRK19768.1 - 0.072 12.1 2.0 0.092 11.7 0.1 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Nuc_deoxyri_tr2 PF15891.5 CRK19768.1 - 0.13 12.5 0.2 1.6 9.1 0.0 2.3 2 0 0 2 2 2 0 Nucleoside 2-deoxyribosyltransferase like DUF3246 PF11596.8 CRK19768.1 - 0.2 11.1 2.6 0.33 10.4 2.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Cwf_Cwc_15 PF04889.12 CRK19768.1 - 0.24 11.1 13.3 0.3 10.8 12.6 1.4 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 CRK19768.1 - 8.4 5.6 8.3 14 4.9 8.3 1.4 1 0 0 1 1 1 0 NOA36 protein HAD_2 PF13419.6 CRK19769.1 - 3.8e-18 66.2 0.0 5.1e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CRK19769.1 - 7.2e-11 42.8 0.0 2.4e-05 24.7 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 CRK19769.1 - 0.0035 17.8 0.0 0.0063 16.9 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase GHL6 PF14871.6 CRK19769.1 - 0.015 15.4 0.1 0.042 14.0 0.0 1.8 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase 6 Hydrolase_6 PF13344.6 CRK19769.1 - 0.091 12.9 0.0 4.8 7.4 0.0 2.7 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase cwf18 PF08315.12 CRK19769.1 - 0.18 12.5 0.0 0.26 11.9 0.0 1.2 1 0 0 1 1 1 0 cwf18 pre-mRNA splicing factor Homeodomain PF00046.29 CRK19770.1 - 7.4e-13 48.1 3.4 1.8e-12 46.9 3.4 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CRK19770.1 - 0.0015 18.4 0.4 0.0043 16.9 0.4 1.8 1 0 0 1 1 1 1 Homeobox KN domain ADIP PF11559.8 CRK19770.1 - 3.8 7.6 11.4 12 5.9 10.9 1.8 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding Pkinase PF00069.25 CRK19771.1 - 4.3e-67 226.3 0.0 9.2e-67 225.2 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK19771.1 - 1.1e-35 123.2 0.0 2e-35 122.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CRK19771.1 - 9.7e-06 25.1 0.0 2.2e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like NOG1_N PF17835.1 CRK19771.1 - 0.0025 17.8 15.5 0.017 15.1 0.2 5.7 6 0 0 6 6 6 1 NOG1 N-terminal helical domain DUF229 PF02995.17 CRK19771.1 - 0.0041 15.8 0.0 2.7 6.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF229) SF3a60_bindingd PF12108.8 CRK19771.1 - 0.0091 15.9 0.1 7.6 6.5 0.0 2.7 2 0 0 2 2 2 2 Splicing factor SF3a60 binding domain Pkinase_fungal PF17667.1 CRK19771.1 - 0.014 14.2 0.0 0.028 13.2 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase DUF2987 PF11205.8 CRK19771.1 - 0.015 15.2 0.0 8.7 6.2 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2987) DUF3287 PF11690.8 CRK19771.1 - 0.02 14.6 0.2 12 5.6 0.0 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) DUF155 PF02582.14 CRK19771.1 - 0.024 14.7 0.3 15 5.6 0.0 3.1 2 0 0 2 2 2 0 Uncharacterised ACR, YagE family COG1723 APH PF01636.23 CRK19771.1 - 0.028 14.3 0.0 0.26 11.2 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family SnAC PF14619.6 CRK19771.1 - 0.032 14.8 5.7 10 6.8 0.0 4.1 3 0 0 3 3 3 0 Snf2-ATP coupling, chromatin remodelling complex Xpo1 PF08389.12 CRK19771.1 - 0.033 14.3 3.5 12 6.0 0.1 3.9 4 0 0 4 4 4 0 Exportin 1-like protein Syntaxin-6_N PF09177.11 CRK19771.1 - 0.035 14.6 2.9 17 6.0 0.0 4.3 3 0 0 3 3 3 0 Syntaxin 6, N-terminal Amidohydro_2 PF04909.14 CRK19771.1 - 0.057 13.2 0.0 12 5.6 0.0 2.6 2 0 0 2 2 2 0 Amidohydrolase Arrestin_C PF02752.22 CRK19771.1 - 0.064 13.7 0.3 27 5.2 0.0 3.0 4 0 0 4 4 2 0 Arrestin (or S-antigen), C-terminal domain MmcB-like PF06319.12 CRK19771.1 - 0.064 12.9 2.5 74 3.0 0.0 4.1 4 0 0 4 4 4 0 DNA repair protein MmcB-like Seadorna_VP7 PF07387.11 CRK19771.1 - 0.092 11.8 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 ACT_4 PF13291.6 CRK19771.1 - 0.099 13.3 4.8 83 3.9 0.1 4.4 4 0 0 4 4 4 0 ACT domain zf-C4_ClpX PF06689.13 CRK19771.1 - 0.16 11.9 1.1 25 4.8 0.1 2.6 2 0 0 2 2 2 0 ClpX C4-type zinc finger Lentiviral_Tat PF02998.14 CRK19771.1 - 0.22 11.6 2.3 23 5.1 0.2 2.8 2 0 0 2 2 2 0 Lentiviral Tat protein YqzE PF14038.6 CRK19771.1 - 6.4 6.9 6.9 22 5.2 0.2 3.3 4 0 0 4 4 2 0 YqzE-like protein PilX_N PF14341.6 CRK19773.1 - 0.09 12.7 1.1 0.19 11.7 1.1 1.5 1 0 0 1 1 1 0 PilX N-terminal PilX_N PF14341.6 CRK19774.1 - 0.098 12.6 1.1 0.19 11.7 1.1 1.4 1 0 0 1 1 1 0 PilX N-terminal Ofd1_CTDD PF10637.9 CRK19775.1 - 3.5e-86 288.7 2.1 1.2e-83 280.4 2.2 2.3 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 CRK19775.1 - 1.5e-05 25.6 0.0 4.4e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Coilin_N PF15862.5 CRK19775.1 - 0.0059 16.4 2.9 0.0059 16.4 2.9 3.8 4 0 0 4 4 4 2 Coilin N-terminus SpoIIP PF07454.11 CRK19775.1 - 0.83 9.1 14.5 1.6 8.1 8.1 2.5 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) FAM60A PF15396.6 CRK19775.1 - 4.4 7.3 19.3 0.81 9.7 7.9 2.9 3 0 0 3 3 3 0 Protein Family FAM60A Spt20 PF12090.8 CRK19775.1 - 4.5 6.8 17.3 1.9 8.0 0.6 2.5 2 0 0 2 2 2 0 Spt20 family VCX_VCY PF15231.6 CRK19776.1 - 0.029 15.1 11.4 0.029 15.1 11.4 2.8 3 0 0 3 3 3 0 Variable charge X/Y family SoxD PF04267.12 CRK19776.1 - 0.15 12.2 0.7 3.4 7.8 0.1 2.7 2 0 0 2 2 2 0 Sarcosine oxidase, delta subunit family CCDC106 PF15794.5 CRK19776.1 - 1 9.0 21.6 0.41 10.3 4.1 3.1 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 106 SP_C-Propep PF08999.10 CRK19777.1 - 1.1 9.0 8.4 2 8.3 0.1 2.5 2 0 0 2 2 2 0 Surfactant protein C, N terminal propeptide Neur_chan_memb PF02932.16 CRK19777.1 - 4 7.4 5.8 0.22 11.6 0.4 1.5 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region GCV_T PF01571.21 CRK19778.1 - 7.4e-93 310.6 0.5 4.4e-46 157.3 0.1 2.2 1 1 1 2 2 2 2 Aminomethyltransferase folate-binding domain V-ATPase_H_N PF03224.14 CRK19778.1 - 1.9e-74 250.8 0.0 2.7e-74 250.3 0.0 1.2 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 CRK19778.1 - 7.9e-33 113.1 0.0 4.7e-32 110.5 0.0 2.4 3 0 0 3 3 3 1 V-ATPase subunit H GCV_T_C PF08669.11 CRK19778.1 - 1.8e-21 75.8 0.5 3.8e-21 74.8 0.5 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Metallophos PF00149.28 CRK19778.1 - 1.6e-05 25.5 0.2 4.2e-05 24.1 0.2 1.7 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Podoplanin PF05808.11 CRK19779.1 - 0.024 14.7 1.9 0.048 13.8 1.9 1.4 1 0 0 1 1 1 0 Podoplanin Glycophorin_A PF01102.18 CRK19779.1 - 0.028 14.7 0.0 0.055 13.7 0.0 1.4 1 0 0 1 1 1 0 Glycophorin A Ribosomal_L6 PF00347.23 CRK19780.1 - 6.9e-19 68.3 0.2 1.1e-10 42.1 0.1 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Vps26 PF03643.15 CRK19781.1 - 1.9e-20 73.0 0.2 2.2e-20 72.8 0.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 IL17R_D_N PF16742.5 CRK19781.1 - 0.04 14.0 0.0 0.048 13.7 0.0 1.1 1 0 0 1 1 1 0 N-terminus of interleukin 17 receptor D V-ATPase_H_N PF03224.14 CRK19782.1 - 5.1e-76 256.0 0.0 8e-76 255.3 0.0 1.3 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 CRK19782.1 - 6.8e-34 116.5 0.0 2.8e-33 114.5 0.0 2.1 3 0 0 3 3 3 1 V-ATPase subunit H Arm PF00514.23 CRK19782.1 - 0.61 10.2 2.6 23 5.2 0.0 3.8 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Podoplanin PF05808.11 CRK19783.1 - 0.02 15.0 1.6 0.043 13.9 1.6 1.5 1 0 0 1 1 1 0 Podoplanin Glycophorin_A PF01102.18 CRK19783.1 - 0.037 14.3 0.0 0.075 13.3 0.0 1.5 1 0 0 1 1 1 0 Glycophorin A Ribosomal_L6 PF00347.23 CRK19784.1 - 2.7e-28 98.5 10.1 6.2e-12 46.0 1.2 3.3 3 0 0 3 3 3 3 Ribosomal protein L6 Vps26 PF03643.15 CRK19785.1 - 5e-32 111.0 0.0 6e-32 110.8 0.0 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Vps26 PF03643.15 CRK19786.1 - 6.5e-130 432.1 0.5 7.7e-130 431.8 0.5 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 CRK19786.1 - 0.0021 18.1 0.6 0.092 12.8 0.6 3.3 1 1 1 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Nup160 PF11715.8 CRK19787.1 - 5.8e-277 919.6 0.0 1.6e-137 459.4 0.0 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Rad51 PF08423.11 CRK19787.1 - 4.1e-190 629.1 5.7 1.8e-94 315.8 0.3 2.3 2 0 0 2 2 2 2 Rad51 YTH PF04146.15 CRK19787.1 - 8.9e-62 207.9 0.0 2.1e-61 206.7 0.0 1.7 1 0 0 1 1 1 1 YT521-B-like domain HSP20 PF00011.21 CRK19787.1 - 2.3e-18 66.2 0.0 4.1e-05 23.6 0.0 4.6 4 0 0 4 4 4 4 Hsp20/alpha crystallin family AAA_25 PF13481.6 CRK19787.1 - 1.2e-16 60.9 0.0 7.4e-07 28.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain RecA PF00154.21 CRK19787.1 - 3.8e-15 56.1 0.1 1.7e-06 27.7 0.1 2.2 2 0 0 2 2 2 2 recA bacterial DNA recombination protein HHH_5 PF14520.6 CRK19787.1 - 1.6e-12 47.8 5.4 3.6e-05 24.3 0.5 3.1 2 0 0 2 2 2 2 Helix-hairpin-helix domain ATPase PF06745.13 CRK19787.1 - 4.7e-10 39.2 0.3 0.0007 19.0 0.0 2.3 2 0 0 2 2 2 2 KaiC TES PF08034.11 CRK19787.1 - 0.0024 18.1 0.7 3.8 7.9 0.1 2.7 2 0 0 2 2 2 2 Trematode eggshell synthesis protein DDE_Tnp_1_2 PF13586.6 CRK19787.1 - 0.025 14.9 0.1 18 5.8 0.0 2.9 2 0 0 2 2 2 0 Transposase DDE domain PAXNEB PF05625.11 CRK19787.1 - 0.068 12.3 10.9 0.64 9.1 0.1 3.5 5 0 0 5 5 5 0 PAXNEB protein RRM_1 PF00076.22 CRK19787.1 - 0.076 12.9 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HHH PF00633.23 CRK19787.1 - 0.14 12.1 0.6 27 4.9 0.1 2.7 2 0 0 2 2 2 0 Helix-hairpin-helix motif Proteasome PF00227.26 CRK19788.1 - 3.3e-27 95.2 0.4 7.5e-27 94.1 0.4 1.6 1 1 0 1 1 1 1 Proteasome subunit PI3_PI4_kinase PF00454.27 CRK19789.1 - 3.2e-36 125.4 0.1 4.8e-34 118.3 0.1 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 CRK19789.1 - 7.8e-25 87.3 0.0 2.1e-24 86.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) ZT_dimer PF16916.5 CRK19790.1 - 1.8e-09 37.6 0.0 2.8e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Cation_efflux PF01545.21 CRK19790.1 - 0.00015 21.5 0.2 0.00021 21.1 0.2 1.2 1 0 0 1 1 1 1 Cation efflux family PI3_PI4_kinase PF00454.27 CRK19791.1 - 2.8e-36 125.6 0.1 4.5e-34 118.4 0.1 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 CRK19791.1 - 6.1e-25 87.7 0.0 1.6e-24 86.3 0.0 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Aldedh PF00171.22 CRK19792.1 - 1.2e-87 294.4 0.3 9.7e-48 162.8 0.0 2.1 1 1 1 2 2 2 2 Aldehyde dehydrogenase family Cation_efflux PF01545.21 CRK19792.1 - 1.2e-21 77.4 12.2 1.6e-21 77.0 12.2 1.2 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 CRK19792.1 - 1.3e-08 34.9 0.0 2.8e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Aldedh PF00171.22 CRK19795.1 - 4.6e-177 589.2 0.0 5.2e-177 589.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1883 PF08980.10 CRK19799.1 - 3e-05 23.9 0.0 0.5 10.3 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF1883) Sel_put PF04328.13 CRK19799.1 - 0.00034 20.6 2.4 0.81 9.8 0.2 2.7 2 0 0 2 2 2 2 Selenoprotein, putative Clathrin_bdg PF15045.6 CRK19799.1 - 0.0053 16.7 2.0 3.9 7.5 0.1 2.8 2 0 0 2 2 2 2 Clathrin-binding box of Aftiphilin, vesicle trafficking ATP-synt_E PF05680.12 CRK19799.1 - 0.11 12.8 7.8 2.6 8.4 1.1 2.8 2 0 0 2 2 2 0 ATP synthase E chain DUF697 PF05128.12 CRK19799.1 - 0.15 11.7 0.8 17 5.1 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF697) RXT2_N PF08595.11 CRK19799.1 - 0.46 10.5 11.7 1.7 8.6 0.8 3.0 3 0 0 3 3 3 0 RXT2-like, N-terminal Ntox37 PF15535.6 CRK19799.1 - 1 9.8 8.9 12 6.4 0.4 4.0 3 0 0 3 3 3 0 Bacterial toxin 37 FAM176 PF14851.6 CRK19799.1 - 1.6 8.3 16.7 5.5 6.6 2.4 3.8 3 0 0 3 3 3 0 FAM176 family GCIP PF13324.6 CRK19799.1 - 2.4 7.7 9.7 5.5 6.5 0.4 2.7 3 0 0 3 3 3 0 Grap2 and cyclin-D-interacting DMRL_synthase PF00885.19 CRK19800.1 - 3.5e-55 185.7 0.0 4.5e-55 185.3 0.0 1.1 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase HATPase_c_3 PF13589.6 CRK19801.1 - 1.2e-15 57.5 0.0 2.2e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CRK19801.1 - 5.8e-08 33.2 0.0 1.5e-07 31.9 0.0 1.6 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TBX PF12598.8 CRK19801.1 - 0.032 15.0 3.0 0.037 14.8 0.5 2.2 2 0 0 2 2 2 0 T-box transcription factor DMRL_synthase PF00885.19 CRK19802.1 - 2.1e-55 186.4 0.0 2.6e-55 186.1 0.0 1.1 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase HATPase_c_3 PF13589.6 CRK19803.1 - 1.9e-15 56.9 0.0 3.4e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.19 CRK19803.1 - 5.3e-09 35.8 0.0 1.5e-08 34.4 0.0 1.7 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.26 CRK19803.1 - 6.1e-08 33.2 0.0 1.8e-07 31.7 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TRP_N PF14558.6 CRK19805.1 - 2.6e-55 186.6 0.0 2.3e-26 92.8 0.0 2.3 2 0 0 2 2 2 2 ML-like domain TRP PF06011.12 CRK19805.1 - 1.6e-37 129.3 26.5 9.1e-36 123.5 26.5 2.2 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel NDUF_B12 PF08122.12 CRK19805.1 - 0.031 14.3 0.2 23 5.1 0.0 3.4 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase B12 subunit family TRP PF06011.12 CRK19806.1 - 4e-28 98.3 23.8 5.5e-28 97.9 23.8 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TPR_12 PF13424.6 CRK19806.1 - 3.9e-05 23.9 0.8 9.1e-05 22.7 0.8 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 CRK19806.1 - 0.00023 21.1 0.4 0.0067 16.4 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 CRK19806.1 - 0.00068 20.1 1.3 0.0024 18.4 1.3 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 CRK19806.1 - 0.0065 16.6 0.2 0.088 13.1 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 CRK19806.1 - 0.023 14.4 1.1 0.034 13.8 0.1 1.8 2 0 0 2 2 2 0 TPR repeat TPR_1 PF00515.28 CRK19806.1 - 0.03 14.1 0.6 0.072 12.9 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_21 PF09976.9 CRK19806.1 - 0.054 13.2 3.6 0.082 12.6 1.9 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain TPR_16 PF13432.6 CRK19806.1 - 0.07 13.8 0.2 0.07 13.8 0.2 3.3 3 1 0 4 4 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 CRK19806.1 - 0.12 12.4 0.9 0.6 10.3 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 CRK19806.1 - 0.29 12.1 11.6 0.43 11.5 0.0 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat RWD PF05773.22 CRK19808.1 - 1.1e-42 145.0 2.7 1.5e-19 70.4 0.1 3.4 3 0 0 3 3 3 3 RWD domain DFRP_C PF16543.5 CRK19808.1 - 1.5e-06 28.6 3.7 3.2e-06 27.5 3.7 1.5 1 0 0 1 1 1 1 DRG Family Regulatory Proteins, Tma46 DUF1381 PF07129.11 CRK19808.1 - 0.1 12.5 0.4 23 4.9 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1381) DUF4096 PF13340.6 CRK19808.1 - 0.13 12.5 0.0 1.2e+02 3.0 0.0 3.4 3 0 0 3 3 3 0 Putative transposase of IS4/5 family (DUF4096) DUF2489 PF10675.9 CRK19808.1 - 0.99 9.3 8.3 11 5.9 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2489) LPD15 PF18828.1 CRK19809.1 - 0.025 14.4 0.5 0.075 12.9 0.5 1.8 1 0 0 1 1 1 0 Large polyvalent-protein-associated domain 15 F-protein PF00469.20 CRK19809.1 - 5 6.7 8.0 0.54 9.8 1.6 2.4 1 1 0 2 2 2 0 Negative factor, (F-Protein) or Nef CPL PF08144.11 CRK19810.1 - 4.1e-84 280.1 1.2 1.9e-40 138.5 0.0 4.9 5 0 0 5 5 5 2 CPL (NUC119) domain KN17_SH3 PF18131.1 CRK19810.1 - 0.016 15.3 0.2 11 6.2 0.0 2.6 2 0 0 2 2 2 0 KN17 SH3-like C-terminal domain DUF3206 PF11472.8 CRK19810.1 - 0.032 14.2 0.0 14 5.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3206) Mucin15 PF15672.5 CRK19810.1 - 0.043 13.3 0.1 12 5.2 0.0 2.6 2 0 0 2 2 2 0 Cell-membrane associated Mucin15 EII-Sor PF03609.14 CRK19810.1 - 0.058 12.8 0.0 11 5.4 0.0 2.6 2 0 0 2 2 2 0 PTS system sorbose-specific iic component Stap_Strp_tox_C PF02876.17 CRK19810.1 - 0.09 13.1 0.0 24 5.3 0.0 2.6 2 0 0 2 2 2 0 Staphylococcal/Streptococcal toxin, beta-grasp domain DAP10 PF07213.11 CRK19810.1 - 0.1 12.5 0.4 26 4.9 0.1 2.6 2 0 0 2 2 2 0 DAP10 membrane protein TGF_beta_GS PF08515.12 CRK19810.1 - 0.15 11.6 0.1 36 4.0 0.0 3.2 2 0 0 2 2 2 0 Transforming growth factor beta type I GS-motif DUF3147 PF11345.8 CRK19810.1 - 0.41 11.0 2.2 32 4.9 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3147) DUF1097 PF06496.11 CRK19810.1 - 0.62 10.2 5.1 12 6.0 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1097) RNA_pol_Rpb4 PF03874.16 CRK19811.1 - 3.3e-26 92.0 5.6 5e-26 91.4 5.6 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb4 Telomere_res PF16684.5 CRK19811.1 - 0.043 13.3 0.2 0.062 12.8 0.2 1.1 1 0 0 1 1 1 0 Telomere resolvase NAM-associated PF14303.6 CRK19811.1 - 0.064 14.0 0.5 0.098 13.4 0.5 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Sybindin PF04099.12 CRK19812.1 - 2.8e-76 254.2 0.0 1.5e-52 177.3 0.0 2.0 2 0 0 2 2 2 2 Sybindin-like family Sedlin_N PF04628.13 CRK19812.1 - 4.6e-07 30.0 0.0 6.6e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region VirE1 PF12189.8 CRK19812.1 - 0.059 13.5 0.4 17 5.6 0.1 2.5 2 0 0 2 2 2 0 Single-strand DNA-binding protein RadC PF04002.15 CRK19812.1 - 0.11 12.5 0.0 19 5.2 0.0 2.5 2 0 0 2 2 2 0 RadC-like JAB domain Blt1_C PF17183.4 CRK19812.1 - 0.16 11.6 0.0 12 5.6 0.0 2.3 2 0 0 2 2 2 0 Get5 carboxyl domain RNA_pol_Rpb4 PF03874.16 CRK19813.1 - 4e-26 91.8 5.6 5.9e-26 91.2 5.6 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb4 NAM-associated PF14303.6 CRK19813.1 - 0.019 15.7 0.4 0.028 15.2 0.4 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Telomere_res PF16684.5 CRK19813.1 - 0.048 13.1 0.2 0.071 12.6 0.2 1.2 1 0 0 1 1 1 0 Telomere resolvase VWA_2 PF13519.6 CRK19814.1 - 8.5e-27 93.9 0.2 2.2e-26 92.6 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 CRK19814.1 - 6.8e-11 42.7 0.3 9.2e-11 42.3 0.3 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.14 CRK19814.1 - 8.9e-08 32.2 0.0 1.3e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.20 CRK19814.1 - 0.0075 16.1 1.1 0.022 14.7 1.1 1.8 1 0 0 1 1 1 1 Ubiquitin interaction motif DUF243 PF03103.17 CRK19814.1 - 0.2 12.0 0.1 0.2 12.0 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF243) Nbl1_Borealin_N PF10444.9 CRK19815.1 - 2.1e-19 68.9 3.7 3e-19 68.4 3.7 1.2 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal DUF3138 PF11336.8 CRK19815.1 - 1 7.9 6.3 1.1 7.7 6.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) SUI1 PF01253.22 CRK19816.1 - 2.9e-24 85.4 0.3 2.9e-24 85.4 0.3 2.2 3 0 0 3 3 3 1 Translation initiation factor SUI1 VWA_2 PF13519.6 CRK19816.1 - 5.7e-21 75.2 0.1 2e-20 73.4 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain Ssl1 PF04056.14 CRK19816.1 - 0.00029 20.7 0.0 0.0006 19.7 0.0 1.5 1 0 0 1 1 1 1 Ssl1-like Img2 PF05046.14 CRK19816.1 - 0.016 15.5 0.2 0.048 14.0 0.0 1.9 2 1 0 2 2 2 0 Mitochondrial large subunit ribosomal protein (Img2) ACOX PF01756.19 CRK19816.1 - 0.03 13.9 0.1 0.049 13.2 0.1 1.2 1 0 0 1 1 1 0 Acyl-CoA oxidase MscS_TM PF12794.7 CRK19816.1 - 0.43 9.4 2.8 0.71 8.7 2.8 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 XhlA PF10779.9 CRK19816.1 - 0.92 9.8 4.6 0.65 10.3 0.4 2.6 3 0 0 3 3 3 0 Haemolysin XhlA Nbl1_Borealin_N PF10444.9 CRK19817.1 - 2.9e-18 65.2 3.5 6.9e-18 64.0 3.5 1.7 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal EspG PF06872.11 CRK19817.1 - 0.015 13.9 0.3 3.5 6.1 0.0 2.2 2 0 0 2 2 2 0 EspG protein DUF596 PF04591.12 CRK19817.1 - 0.16 12.1 0.0 0.36 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF596 Zn_clus PF00172.18 CRK19818.1 - 0.00023 21.2 25.5 0.0033 17.5 3.9 3.3 4 0 0 4 4 4 2 Fungal Zn(2)-Cys(6) binuclear cluster domain EthD PF07110.11 CRK19818.1 - 0.0029 18.7 1.3 12 7.2 0.0 4.2 4 0 0 4 4 4 2 EthD domain Orthopox_F7 PF05813.12 CRK19818.1 - 0.038 14.1 1.2 7.4 6.8 0.1 2.4 2 0 0 2 2 2 0 Orthopoxvirus F7 protein zf-C2H2_2 PF12756.7 CRK19818.1 - 0.049 14.0 0.9 8.3 6.8 0.0 3.8 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) OxoDH_E1alpha_N PF12573.8 CRK19818.1 - 0.28 11.0 3.0 15 5.4 0.2 2.6 2 0 0 2 2 2 0 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal Choline_kinase PF01633.20 CRK19821.1 - 2.2e-33 115.7 0.0 2.9e-32 112.0 0.0 2.2 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 CRK19821.1 - 1.7e-09 38.0 0.1 4.2e-09 36.7 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 CRK19821.1 - 0.017 14.4 0.0 0.1 11.9 0.0 2.0 1 1 0 1 1 1 0 Ecdysteroid kinase DUF1679 PF07914.11 CRK19821.1 - 0.042 12.7 0.0 0.055 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 CRK19822.1 - 4.3e-50 170.3 0.0 4e-49 167.1 0.0 2.1 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 CRK19822.1 - 9.7e-11 42.0 0.1 2.3e-10 40.8 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 CRK19822.1 - 0.038 13.3 0.0 1.1 8.5 0.0 2.5 3 0 0 3 3 3 0 Ecdysteroid kinase DUF1679 PF07914.11 CRK19822.1 - 0.076 11.9 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) NPR3 PF03666.13 CRK19823.1 - 1.3e-143 479.2 0.0 1.7e-143 478.9 0.0 1.2 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 HLH PF00010.26 CRK19824.1 - 1.8e-12 47.0 0.0 7.8e-12 45.0 0.0 2.0 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF3544 PF12064.8 CRK19824.1 - 0.04 14.2 5.1 0.048 13.9 4.1 1.6 2 0 0 2 2 2 0 Protein kinase C-binding protein 1 HLH PF00010.26 CRK19825.1 - 2.8e-12 46.4 0.0 1.1e-11 44.5 0.0 1.9 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF3544 PF12064.8 CRK19825.1 - 0.023 15.0 4.1 0.069 13.4 4.1 1.7 1 0 0 1 1 1 0 Protein kinase C-binding protein 1 RNA_pol_I_TF PF04090.12 CRK19826.1 - 0.19 11.2 0.7 0.27 10.7 0.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific initiation factor Got1 PF04178.12 CRK19827.1 - 1.7e-33 115.4 16.0 2.3e-33 115.0 16.0 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family PMP22_Claudin PF00822.20 CRK19827.1 - 0.89 9.4 7.4 0.86 9.5 5.6 1.7 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin family EF-hand_1 PF00036.32 CRK19828.1 - 1.5e-37 124.4 6.6 7.8e-10 37.6 2.3 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CRK19828.1 - 2.3e-31 108.0 3.4 1.1e-16 61.0 0.4 2.0 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CRK19828.1 - 5.6e-31 103.8 1.0 1.1e-07 31.2 0.0 4.1 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 CRK19828.1 - 1.1e-27 95.7 9.2 2.1e-14 53.1 0.3 3.9 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 CRK19828.1 - 3e-24 83.4 6.7 4.7e-06 25.9 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 CRK19828.1 - 2.1e-13 50.4 0.1 9e-06 25.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 CRK19828.1 - 9.9e-07 28.7 4.1 0.022 14.7 0.1 3.0 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CRK19828.1 - 8.6e-06 26.1 0.0 0.039 14.3 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 CRK19828.1 - 2.5e-05 25.1 0.0 0.00067 20.5 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain EF-hand_14 PF17959.1 CRK19828.1 - 6.5e-05 23.2 0.1 0.16 12.3 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain Dockerin_1 PF00404.18 CRK19828.1 - 0.00047 20.3 0.6 0.35 11.1 0.2 2.6 2 1 0 2 2 2 2 Dockerin type I domain Caleosin PF05042.13 CRK19828.1 - 0.038 13.9 0.0 0.73 9.7 0.0 2.6 2 2 0 2 2 2 0 Caleosin related protein SurA_N_3 PF13624.6 CRK19828.1 - 0.043 13.6 0.0 0.61 9.9 0.0 2.1 1 1 1 2 2 2 0 SurA N-terminal domain EFhand_Ca_insen PF08726.10 CRK19828.1 - 0.046 13.8 0.0 0.17 12.0 0.0 1.9 2 0 0 2 2 2 0 Ca2+ insensitive EF hand DUF5580 PF17743.1 CRK19828.1 - 0.052 12.1 0.0 0.092 11.3 0.0 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5580) UPF0154 PF03672.13 CRK19828.1 - 0.055 13.5 0.0 1.2 9.2 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) DUF1128 PF06569.11 CRK19828.1 - 0.066 13.2 0.5 4.9 7.2 0.0 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1128) VCBS PF13517.6 CRK19828.1 - 1.4 9.5 5.4 53 4.5 4.7 2.9 2 1 1 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella CYSTM PF12734.7 CRK19829.1 - 0.0027 18.0 67.2 0.06 13.7 45.4 3.9 1 1 1 2 2 2 1 Cysteine-rich TM module stress tolerance WW PF00397.26 CRK19831.1 - 3e-13 49.6 6.3 7.2e-13 48.4 6.3 1.7 1 0 0 1 1 1 1 WW domain Gly-zipper_Omp PF13488.6 CRK19831.1 - 0.03 14.3 5.7 0.088 12.8 5.7 1.8 1 0 0 1 1 1 0 Glycine zipper Myb_DNA-bind_6 PF13921.6 CRK19833.1 - 0.00023 21.4 0.2 0.00036 20.7 0.2 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 CRK19833.1 - 0.056 13.6 1.0 0.094 12.9 1.0 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain MBOAT_2 PF13813.6 CRK19834.1 - 8e-15 54.9 2.5 2.4e-14 53.3 2.5 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Fungal_trans_2 PF11951.8 CRK19836.1 - 1.7e-10 40.3 0.6 2.5e-10 39.7 0.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK19836.1 - 1.2e-09 38.1 8.1 2.2e-09 37.3 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RTA1 PF04479.13 CRK19837.1 - 5.4e-70 235.2 11.2 5.4e-70 235.2 11.2 1.7 2 0 0 2 2 2 1 RTA1 like protein Kei1 PF08552.11 CRK19837.1 - 0.026 14.4 0.1 0.05 13.5 0.1 1.5 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF4818 PF16089.5 CRK19837.1 - 0.2 12.1 3.7 0.37 11.3 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4818) RTA1 PF04479.13 CRK19841.1 - 1.8e-74 249.9 8.9 1.8e-74 249.9 8.9 1.4 2 0 0 2 2 2 1 RTA1 like protein DUF5134 PF17197.4 CRK19841.1 - 0.91 9.4 6.3 38 4.1 6.3 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF5134) Glyco_hydro_18 PF00704.28 CRK19844.1 - 3.2e-79 266.9 3.0 4.7e-79 266.3 3.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 NOA36 PF06524.12 CRK19844.1 - 0.27 10.5 11.4 0.4 10.0 11.4 1.1 1 0 0 1 1 1 0 NOA36 protein DUF4614 PF15391.6 CRK19844.1 - 5.4 7.0 17.9 8.8 6.3 17.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) GEMIN8 PF15348.6 CRK19844.1 - 6.6 7.0 9.9 11 6.3 9.9 1.2 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Zip PF02535.22 CRK19844.1 - 7.8 5.6 6.8 11 5.1 6.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter HECT_2 PF09814.9 CRK19846.1 - 3e-96 322.5 0.0 3.8e-96 322.2 0.0 1.1 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding IU_nuc_hydro PF01156.19 CRK19846.1 - 2e-55 188.5 0.0 5e-55 187.2 0.0 1.7 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Ribosomal_L32p PF01783.23 CRK19846.1 - 0.025 14.8 0.6 7.8 6.8 0.0 2.4 2 0 0 2 2 2 0 Ribosomal L32p protein family Transketolase_C PF02780.20 CRK19846.1 - 0.072 13.0 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 Transketolase, C-terminal domain Cytochrom_B558a PF05038.13 CRK19846.1 - 1.1 8.8 3.8 19 4.8 4.0 2.4 2 0 0 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit LSM PF01423.22 CRK19848.1 - 0.0016 18.1 0.0 0.0029 17.3 0.0 1.4 1 0 0 1 1 1 1 LSM domain zf-AD PF07776.15 CRK19854.1 - 0.043 14.0 1.7 0.095 13.0 1.7 1.6 1 0 0 1 1 1 0 Zinc-finger associated domain (zf-AD) NHase_beta PF02211.15 CRK19854.1 - 0.15 12.0 0.0 0.4 10.7 0.0 1.6 2 0 0 2 2 2 0 Nitrile hydratase beta subunit SH3BGR PF04908.15 CRK19856.1 - 0.00055 20.0 0.0 0.00061 19.9 0.0 1.0 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein adh_short PF00106.25 CRK19860.1 - 1.9e-30 105.8 0.8 2.7e-30 105.3 0.4 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK19860.1 - 7.3e-21 74.8 1.6 1.3e-20 74.0 1.6 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK19860.1 - 9.2e-14 51.7 0.3 4.9e-13 49.4 0.3 2.1 2 1 0 2 2 2 1 KR domain Epimerase PF01370.21 CRK19860.1 - 0.00071 19.1 0.7 0.0036 16.8 0.7 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 CRK19860.1 - 0.0075 15.4 0.0 0.0089 15.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Sugar_tr PF00083.24 CRK19862.1 - 2.9e-55 187.9 5.7 3.6e-54 184.3 5.7 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter DHDPS PF00701.22 CRK19863.1 - 2.3e-37 128.3 0.0 2.8e-37 128.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family FMN_dh PF01070.18 CRK19865.1 - 4.1e-101 338.5 0.1 9.7e-100 334.0 0.1 2.0 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 CRK19865.1 - 3.8e-18 65.4 0.0 1.1e-17 63.9 0.0 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 CRK19865.1 - 7.8e-05 22.0 0.0 0.00015 21.0 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 CRK19865.1 - 0.00053 19.1 0.9 0.0038 16.3 0.5 2.4 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 CRK19865.1 - 0.0014 18.0 0.0 0.14 11.5 0.0 2.3 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG NMO PF03060.15 CRK19865.1 - 0.0049 16.3 0.0 0.0082 15.6 0.0 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase GPHH PF16905.5 CRK19865.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Voltage-dependent L-type calcium channel, IQ-associated Nup54_C PF18437.1 CRK19865.1 - 0.18 11.7 0.1 0.4 10.6 0.1 1.5 1 0 0 1 1 1 0 Nup54 C-terminal interacting domain Epimerase PF01370.21 CRK19867.1 - 3.1e-21 75.9 0.0 3.9e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CRK19867.1 - 1.3e-13 50.7 0.0 1.6e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 CRK19867.1 - 3.9e-11 42.9 0.0 5.8e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 CRK19867.1 - 5.2e-07 29.1 0.0 0.011 15.0 0.0 2.6 2 1 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 CRK19867.1 - 7e-05 22.1 0.0 9.5e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 CRK19867.1 - 0.00019 21.4 0.0 0.00029 20.8 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 CRK19867.1 - 0.00093 18.7 0.0 0.016 14.7 0.0 2.6 2 1 0 2 2 2 1 short chain dehydrogenase Ldh_1_N PF00056.23 CRK19867.1 - 0.0013 18.8 0.0 0.002 18.2 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain NmrA PF05368.13 CRK19867.1 - 0.012 15.1 0.0 0.25 10.9 0.0 2.1 2 0 0 2 2 2 0 NmrA-like family Polysacc_synt_2 PF02719.15 CRK19867.1 - 0.035 13.3 0.0 0.15 11.1 0.0 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein KR PF08659.10 CRK19867.1 - 0.089 12.7 0.0 0.22 11.4 0.0 1.7 1 1 1 2 2 2 0 KR domain Aldo_ket_red PF00248.21 CRK19868.1 - 2.1e-55 188.0 0.0 2.7e-55 187.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Shal-type PF11601.8 CRK19868.1 - 0.16 11.5 0.6 0.33 10.5 0.6 1.5 1 0 0 1 1 1 0 Shal-type voltage-gated potassium channels, N-terminal Fungal_trans PF04082.18 CRK19871.1 - 0.15 11.1 0.1 0.26 10.3 0.1 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain SH3BGR PF04908.15 CRK19873.1 - 0.0029 17.7 0.0 0.012 15.7 0.0 2.2 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Plasmodium_Vir PF05795.11 CRK19873.1 - 0.54 9.6 10.7 0.84 9.0 10.7 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein NPR3 PF03666.13 CRK19873.1 - 3.2 6.4 12.3 4.7 5.9 12.3 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CDC45 PF02724.14 CRK19873.1 - 7 4.8 14.7 11 4.1 14.7 1.2 1 0 0 1 1 1 0 CDC45-like protein AAA PF00004.29 CRK19875.1 - 2.9e-25 89.2 0.0 3.4e-07 30.7 0.0 3.8 3 0 0 3 3 3 3 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CRK19875.1 - 3.8e-06 26.6 0.2 0.19 11.6 0.0 3.3 2 0 0 2 2 2 2 AAA+ lid domain Vps4_C PF09336.10 CRK19875.1 - 1.4e-05 25.0 0.2 3.3 7.8 0.0 5.0 4 0 0 4 4 4 2 Vps4 C terminal oligomerisation domain TetR_C_32 PF09209.11 CRK19875.1 - 0.004 17.1 0.2 0.0089 16.0 0.2 1.5 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain Transglycosylas PF06737.14 CRK19875.1 - 0.041 14.5 0.0 30 5.3 0.0 3.1 3 0 0 3 3 3 0 Transglycosylase-like domain DTHCT PF08070.11 CRK19875.1 - 0.42 11.4 8.8 4.9 8.0 0.5 3.1 2 0 0 2 2 2 0 DTHCT (NUC029) region Abhydro_lipase PF04083.16 CRK19877.1 - 4.2e-19 67.9 0.0 1.2e-18 66.4 0.0 1.8 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 CRK19877.1 - 2.4e-07 30.7 0.1 7.9e-07 29.0 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CRK19877.1 - 0.0007 18.9 0.0 0.0033 16.7 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 ATP11 PF06644.11 CRK19879.1 - 9.2e-97 324.1 0.0 1.2e-95 320.4 0.0 2.4 2 1 0 2 2 2 1 ATP11 protein peroxidase PF00141.23 CRK19879.1 - 1.2e-06 28.4 0.0 2.7e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Peroxidase Filament_head PF04732.14 CRK19879.1 - 2.7 8.9 4.9 2.4 9.1 0.4 2.5 2 0 0 2 2 2 0 Intermediate filament head (DNA binding) region Abhydro_lipase PF04083.16 CRK19881.1 - 6.1e-19 67.4 0.0 1.9e-18 65.8 0.0 1.8 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 CRK19881.1 - 2.2e-07 30.8 0.1 6.6e-07 29.2 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CRK19881.1 - 0.00091 18.6 0.0 0.0037 16.5 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 ATP11 PF06644.11 CRK19882.1 - 5.4e-95 318.3 0.0 6.8e-95 317.9 0.0 1.1 1 0 0 1 1 1 1 ATP11 protein CDC73_N PF16050.5 CRK19882.1 - 0.092 12.1 1.4 1.8 7.8 0.1 2.2 2 0 0 2 2 2 0 Paf1 complex subunit CDC73 N-terminal DUF2461 PF09365.10 CRK19882.1 - 0.18 11.7 0.8 0.27 11.2 0.2 1.6 2 0 0 2 2 2 0 Conserved hypothetical protein (DUF2461) NUDE_C PF04880.13 CRK19882.1 - 2.7 8.5 12.3 0.39 11.2 8.0 1.8 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region peroxidase PF00141.23 CRK19883.1 - 8.2e-46 156.5 0.0 1.4e-45 155.7 0.0 1.4 1 0 0 1 1 1 1 Peroxidase Cutinase PF01083.22 CRK19884.1 - 4e-46 157.2 2.7 5.2e-46 156.8 2.7 1.1 1 0 0 1 1 1 1 Cutinase DUF2974 PF11187.8 CRK19884.1 - 0.00026 20.6 0.0 0.00047 19.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) PE-PPE PF08237.11 CRK19884.1 - 0.0044 16.6 0.3 0.0071 15.9 0.3 1.4 1 0 0 1 1 1 1 PE-PPE domain Lipase_3 PF01764.25 CRK19884.1 - 0.019 14.9 0.1 0.027 14.4 0.1 1.3 1 0 0 1 1 1 0 Lipase (class 3) VirJ PF06057.11 CRK19884.1 - 0.036 13.9 0.0 0.06 13.2 0.0 1.4 1 1 0 1 1 1 0 Bacterial virulence protein (VirJ) NmrA PF05368.13 CRK19885.1 - 2.7e-33 115.5 0.6 3.5e-33 115.1 0.6 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 CRK19885.1 - 5.7e-25 88.3 0.0 1e-24 87.4 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 CRK19885.1 - 0.0031 17.0 0.2 0.064 12.7 0.2 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CRK19885.1 - 0.067 12.6 0.1 1.1 8.5 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Oxidored_FMN PF00724.20 CRK19886.1 - 3.6e-64 217.2 0.0 5.5e-58 196.9 0.0 2.2 2 0 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family FMO-like PF00743.19 CRK19886.1 - 3.4e-27 95.1 0.0 3.1e-11 42.4 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 CRK19886.1 - 3.4e-15 56.1 0.1 5.4e-12 45.6 0.0 3.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CRK19886.1 - 1e-10 41.4 0.0 0.00024 20.5 0.0 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CRK19886.1 - 7e-07 28.7 0.0 9.2e-05 21.7 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 CRK19886.1 - 1.7e-06 27.9 0.7 0.11 12.0 0.4 3.4 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CRK19886.1 - 3.6e-06 27.1 0.1 1.2e-05 25.5 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 CRK19886.1 - 4.5e-06 26.7 0.1 0.043 13.8 0.0 3.3 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox PF00070.27 CRK19886.1 - 0.0009 19.8 1.0 0.036 14.6 0.2 3.3 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CRK19886.1 - 0.016 14.5 0.1 0.052 12.8 0.1 1.8 2 0 0 2 2 2 0 Thi4 family AP_endonuc_2 PF01261.24 CRK19886.1 - 0.02 14.4 0.0 0.039 13.4 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel HI0933_like PF03486.14 CRK19886.1 - 0.045 12.5 0.1 2.4 6.7 0.2 2.1 2 0 0 2 2 2 0 HI0933-like protein AlaDh_PNT_C PF01262.21 CRK19886.1 - 0.071 12.4 1.0 0.19 11.0 0.0 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain MFS_1 PF07690.16 CRK19887.1 - 8.8e-31 107.1 37.1 4.9e-30 104.7 37.2 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily ACT_3 PF10000.9 CRK19888.1 - 1.3e-22 79.5 0.0 2.1e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 ACT domain ACT_7 PF13840.6 CRK19888.1 - 1.2e-09 37.8 0.0 1.8e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 ACT domain TPR_14 PF13428.6 CRK19889.1 - 2.7e-05 24.6 2.9 0.055 14.3 0.1 5.3 5 1 1 6 6 6 1 Tetratricopeptide repeat Suf PF05843.14 CRK19889.1 - 0.07 13.1 6.0 9 6.2 0.3 3.5 4 0 0 4 4 4 0 Suppressor of forked protein (Suf) Drf_FH3 PF06367.16 CRK19889.1 - 0.16 11.6 0.1 0.46 10.1 0.0 1.7 2 0 0 2 2 2 0 Diaphanous FH3 Domain Syja_N PF02383.18 CRK19890.1 - 5.8e-71 239.4 0.0 1.4e-70 238.1 0.0 1.6 2 0 0 2 2 2 1 SacI homology domain Exo_endo_phos PF03372.23 CRK19890.1 - 7.6e-09 35.4 0.0 1.5e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family TT_ORF1 PF02956.14 CRK19891.1 - 0.11 11.1 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 TT viral orf 1 14-3-3 PF00244.20 CRK19892.1 - 1.1e-106 355.4 0.4 1.4e-106 355.0 0.4 1.1 1 0 0 1 1 1 1 14-3-3 protein AltA1 PF16541.5 CRK19892.1 - 0.035 15.0 2.7 0.058 14.3 0.5 2.1 1 1 1 2 2 2 0 Alternaria alternata allergen 1 Proteasome PF00227.26 CRK19893.1 - 6.6e-40 136.6 0.0 7.4e-40 136.5 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Cutinase PF01083.22 CRK19894.1 - 3.3e-45 154.2 1.6 3.3e-45 154.2 1.6 1.8 2 0 0 2 2 2 1 Cutinase Cation_ATPase_C PF00689.21 CRK19894.1 - 1.3e-19 70.7 4.6 1.8e-19 70.1 4.6 1.2 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus PE-PPE PF08237.11 CRK19894.1 - 0.0072 15.9 0.3 0.012 15.1 0.3 1.3 1 0 0 1 1 1 1 PE-PPE domain DUF2974 PF11187.8 CRK19894.1 - 0.014 15.0 0.0 0.036 13.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Lipase_3 PF01764.25 CRK19894.1 - 0.055 13.3 0.1 0.14 12.0 0.1 1.7 1 0 0 1 1 1 0 Lipase (class 3) VirJ PF06057.11 CRK19894.1 - 0.17 11.8 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) ACT_3 PF10000.9 CRK19895.1 - 4.7e-22 77.7 0.0 8.6e-22 76.8 0.0 1.4 1 0 0 1 1 1 1 ACT domain ACT_7 PF13840.6 CRK19895.1 - 3.5e-09 36.3 0.0 6.3e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 ACT domain Ytp1 PF10355.9 CRK19895.1 - 0.046 12.9 0.1 0.061 12.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (Ytp1) TPR_14 PF13428.6 CRK19896.1 - 3.8e-05 24.1 0.4 0.05 14.4 0.1 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat Suf PF05843.14 CRK19896.1 - 0.11 12.5 5.5 8.1 6.3 0.3 3.4 4 0 0 4 4 4 0 Suppressor of forked protein (Suf) Syja_N PF02383.18 CRK19897.1 - 1.5e-71 241.4 0.0 3.7e-71 240.0 0.0 1.7 2 0 0 2 2 2 1 SacI homology domain Exo_endo_phos PF03372.23 CRK19897.1 - 7.1e-09 35.5 0.0 1.4e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family 14-3-3 PF00244.20 CRK19898.1 - 2.9e-107 357.3 0.4 3.3e-107 357.0 0.4 1.0 1 0 0 1 1 1 1 14-3-3 protein Lipase_3 PF01764.25 CRK19899.1 - 4.4e-29 101.2 0.0 6.7e-29 100.6 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 CRK19899.1 - 9e-06 26.4 5.8 2.5e-05 25.0 5.8 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 CRK19899.1 - 9.1e-06 25.9 0.1 2.4e-05 24.5 0.0 1.6 2 0 0 2 2 2 1 Thioesterase domain Hydrolase_4 PF12146.8 CRK19899.1 - 0.00034 20.0 0.0 0.0006 19.1 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 CRK19899.1 - 0.0079 15.9 0.1 0.021 14.5 0.0 1.6 2 0 0 2 2 2 1 Putative esterase Abhydrolase_1 PF00561.20 CRK19899.1 - 0.018 14.7 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2974 PF11187.8 CRK19899.1 - 0.068 12.7 0.0 0.31 10.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) PGAP1 PF07819.13 CRK19899.1 - 0.13 11.9 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DUF676 PF05057.14 CRK19899.1 - 0.16 11.4 0.0 1.1 8.7 0.0 1.9 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Ribosomal_L36e PF01158.18 CRK19900.1 - 4e-42 142.4 5.2 4.5e-42 142.2 5.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e MRP-L28 PF09812.9 CRK19900.1 - 0.0093 16.1 1.9 0.011 15.9 1.9 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 PBS_linker_poly PF00427.21 CRK19900.1 - 0.11 12.5 0.3 0.14 12.2 0.3 1.1 1 0 0 1 1 1 0 Phycobilisome Linker polypeptide DUF2207 PF09972.9 CRK19900.1 - 0.13 10.9 0.0 0.14 10.9 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) E1-E2_ATPase PF00122.20 CRK19901.1 - 3.4e-48 163.6 5.6 3.7e-48 163.4 2.5 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 CRK19901.1 - 1.1e-23 84.7 2.6 4e-22 79.5 2.6 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CRK19901.1 - 8.2e-22 77.1 0.0 1.8e-21 76.0 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CRK19901.1 - 7.5e-09 35.7 1.9 1.2e-06 28.4 1.3 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CRK19901.1 - 2.2e-06 27.3 0.1 5.6e-06 26.0 0.1 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase_C PF00689.21 CRK19901.1 - 5.1e-06 26.3 0.6 9.4e-06 25.4 0.1 1.7 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus HAD PF12710.7 CRK19901.1 - 1.2e-05 25.8 0.0 4.4e-05 24.0 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase ArsA_ATPase PF02374.15 CRK19901.1 - 0.026 13.7 0.0 0.072 12.3 0.0 1.7 1 0 0 1 1 1 0 Anion-transporting ATPase SBDS PF01172.18 CRK19903.1 - 1.6e-24 85.7 0.2 1.9e-24 85.5 0.2 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein OPA3 PF07047.12 CRK19904.1 - 2.7e-45 153.2 9.4 5.4e-45 152.2 9.4 1.6 1 1 0 1 1 1 1 Optic atrophy 3 protein (OPA3) Med3 PF11593.8 CRK19904.1 - 0.052 12.7 2.6 0.068 12.4 2.6 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Bac_luciferase PF00296.20 CRK19904.1 - 0.077 12.4 3.3 0.13 11.7 3.3 1.3 1 0 0 1 1 1 0 Luciferase-like monooxygenase Presenilin PF01080.17 CRK19904.1 - 0.1 11.4 1.6 0.098 11.4 1.6 1.2 1 0 0 1 1 1 0 Presenilin CCDC-167 PF15188.6 CRK19904.1 - 0.12 12.8 0.6 0.12 12.8 0.6 2.8 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 JAKMIP_CC3 PF16034.5 CRK19904.1 - 0.61 10.0 17.5 0.34 10.8 10.0 2.1 2 0 0 2 2 2 0 JAKMIP CC3 domain DUF4407 PF14362.6 CRK19904.1 - 1.2 8.4 10.2 4.3 6.6 6.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DDHD PF02862.17 CRK19904.1 - 1.3 9.1 7.5 1.1 9.3 6.6 1.2 1 1 0 1 1 1 0 DDHD domain SLD3 PF08639.10 CRK19904.1 - 1.3 7.7 15.1 4.2 6.0 15.1 1.7 1 1 0 1 1 1 0 DNA replication regulator SLD3 RNA_pol_Rpc4 PF05132.14 CRK19904.1 - 1.5 9.2 8.6 0.21 12.0 4.7 1.5 2 0 0 2 2 1 0 RNA polymerase III RPC4 AAA_23 PF13476.6 CRK19904.1 - 1.6 9.2 15.6 2.2 8.8 9.2 2.1 2 0 0 2 2 2 0 AAA domain Sec62 PF03839.16 CRK19904.1 - 2.3 7.6 7.1 0.72 9.3 3.8 1.7 2 0 0 2 2 2 0 Translocation protein Sec62 Connexin PF00029.19 CRK19904.1 - 2.6 7.7 5.5 1 9.1 2.8 1.6 2 0 0 2 2 2 0 Connexin HAUS6_N PF14661.6 CRK19904.1 - 2.7 7.5 14.6 0.66 9.5 8.4 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus CPSF100_C PF13299.6 CRK19904.1 - 3.4 7.8 9.5 0.2 11.8 3.7 1.7 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF4337 PF14235.6 CRK19904.1 - 4.3 7.4 16.4 2.1 8.4 7.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) V_ATPase_I PF01496.19 CRK19904.1 - 5.1 4.9 8.6 15 3.3 5.2 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family APG6_N PF17675.1 CRK19904.1 - 5.6 7.5 21.5 4.8 7.7 4.8 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF4140 PF13600.6 CRK19904.1 - 5.6 7.5 11.9 3 8.3 0.3 2.4 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Tho2 PF11262.8 CRK19904.1 - 8.9 5.4 12.7 17 4.5 7.2 2.2 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Gly_transf_sug PF04488.15 CRK19905.1 - 6.5e-06 26.7 0.0 1.2e-05 25.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Pkinase PF00069.25 CRK19906.1 - 1.8e-59 201.3 0.0 2.4e-59 200.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK19906.1 - 1.4e-35 122.9 0.0 1.9e-35 122.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 CRK19906.1 - 1.1e-05 25.5 0.1 0.00077 19.6 0.0 3.0 3 0 0 3 3 3 1 POLO box duplicated region Kdo PF06293.14 CRK19906.1 - 0.00028 20.3 0.0 0.0017 17.7 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CRK19906.1 - 0.014 14.2 0.0 0.014 14.2 0.0 1.9 2 0 0 2 2 2 0 Fungal protein kinase Kinase-like PF14531.6 CRK19906.1 - 0.06 12.6 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Sel1 PF08238.12 CRK19907.1 - 4.3e-31 106.6 22.7 6.1e-05 23.6 0.0 6.4 6 0 0 6 6 6 6 Sel1 repeat Chitin_synth_2 PF03142.15 CRK19908.1 - 2.4e-289 960.3 0.9 3.2e-289 959.9 0.9 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 CRK19908.1 - 4.1e-14 52.9 5.7 1.5e-13 51.1 5.7 2.0 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 CRK19908.1 - 5.6e-10 39.5 0.1 3.2e-09 37.0 0.0 2.2 3 0 0 3 3 3 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 CRK19908.1 - 0.00057 19.4 0.0 0.007 15.9 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Cyt-b5 PF00173.28 CRK19908.1 - 0.0035 17.5 0.0 2.8 8.2 0.0 2.7 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.26 CRK19908.1 - 0.011 15.5 0.0 0.08 12.7 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 2 APA3_viroporin PF11289.8 CRK19909.1 - 0.21 11.1 0.0 0.24 10.9 0.0 1.0 1 0 0 1 1 1 0 Coronavirus accessory protein 3a DUF2415 PF10313.9 CRK19910.1 - 0.064 13.2 0.0 0.19 11.7 0.0 1.9 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) WD40 PF00400.32 CRK19910.1 - 0.13 13.2 2.4 1.2 10.1 1.6 3.0 3 0 0 3 3 3 0 WD domain, G-beta repeat Glyco_hydro_17 PF00332.18 CRK19911.1 - 0.02 14.5 0.1 1 8.9 0.1 2.2 2 0 0 2 2 2 0 Glycosyl hydrolases family 17 Glyco_hydro_72 PF03198.14 CRK19911.1 - 0.12 11.5 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Glucanosyltransferase Sortilin-Vps10 PF15902.5 CRK19912.1 - 1.6e-182 607.3 16.2 4.5e-104 348.7 2.5 3.1 2 1 1 3 3 3 3 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 CRK19912.1 - 7.3e-47 159.9 7.3 7.3e-47 159.9 7.3 1.7 2 0 0 2 2 2 1 Sortilin, neurotensin receptor 3, C-terminal Ribonuc_L-PSP PF01042.21 CRK19912.1 - 1e-33 115.9 0.0 2e-33 115.0 0.0 1.5 1 0 0 1 1 1 1 Endoribonuclease L-PSP BNR PF02012.20 CRK19912.1 - 1.2e-05 24.6 11.6 1.4 9.2 0.0 5.9 5 0 0 5 5 5 3 BNR/Asp-box repeat DUF2167 PF09935.9 CRK19912.1 - 0.055 12.6 0.1 0.11 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2167) BNR_6 PF15899.5 CRK19912.1 - 0.33 11.1 2.7 4.3 7.7 0.0 3.6 4 0 0 4 4 4 0 BNR-Asp box repeat Mo-co_dimer PF03404.16 CRK19912.1 - 0.57 10.2 2.0 36 4.3 0.0 3.8 5 0 0 5 5 5 0 Mo-co oxidoreductase dimerisation domain UCR_UQCRX_QCR9 PF05365.12 CRK19913.1 - 7.6e-23 80.2 1.2 8.5e-23 80.1 1.2 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Tricorn_C1 PF14684.6 CRK19913.1 - 0.048 13.7 0.2 0.07 13.2 0.2 1.2 1 0 0 1 1 1 0 Tricorn protease C1 domain PMT PF02366.18 CRK19914.1 - 5.5e-85 284.9 15.8 1.1e-84 283.9 15.8 1.5 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 CRK19914.1 - 1.1e-67 227.5 5.3 1.1e-67 227.5 5.3 2.8 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 CRK19914.1 - 7.6e-21 74.8 0.6 1.3e-20 74.0 0.6 1.4 1 0 0 1 1 1 1 MIR domain RAMP4 PF06624.12 CRK19914.1 - 0.0031 17.5 1.4 2.3 8.3 0.2 2.8 2 0 0 2 2 2 2 Ribosome associated membrane protein RAMP4 YqzE PF14038.6 CRK19914.1 - 7.8 6.6 5.9 13 5.9 0.3 2.9 2 0 0 2 2 2 0 YqzE-like protein CAP59_mtransfer PF11735.8 CRK19915.1 - 1e-86 290.5 0.0 1.3e-86 290.3 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 CAP59_mtransfer PF11735.8 CRK19918.1 - 5e-61 206.5 0.0 6.4e-61 206.1 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 zf-C2H2 PF00096.26 CRK19920.1 - 0.0024 18.2 2.7 0.0068 16.8 2.7 1.8 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CRK19920.1 - 0.043 14.6 2.0 0.17 12.8 2.0 2.1 1 0 0 1 1 1 0 C2H2-type zinc finger ResIII PF04851.15 CRK19921.1 - 1.5e-22 80.4 0.0 2.9e-22 79.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CRK19921.1 - 8.3e-21 74.4 0.0 1.7e-20 73.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CRK19921.1 - 2.8e-18 66.3 0.1 1.1e-17 64.3 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 CRK19921.1 - 7.3e-07 29.1 0.1 1.3e-06 28.3 0.1 1.3 1 0 0 1 1 1 1 SWI2/SNF2 ATPase AAA_22 PF13401.6 CRK19921.1 - 0.0059 16.9 0.0 0.016 15.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain DNA_ligase_A_C PF04679.15 CRK19921.1 - 0.13 12.9 0.2 3.2 8.4 0.1 3.0 3 0 0 3 3 3 0 ATP dependent DNA ligase C terminal region TAP_C PF03943.13 CRK19923.1 - 6e-17 61.0 0.9 5e-16 58.1 0.1 2.3 2 0 0 2 2 2 1 TAP C-terminal domain RRM_9 PF18444.1 CRK19923.1 - 3.5e-05 23.6 0.3 0.00024 20.9 0.3 2.4 2 1 0 2 2 2 1 RNA recognition motif LRR_4 PF12799.7 CRK19923.1 - 6.5e-05 23.2 5.1 0.0025 18.2 0.5 2.8 2 1 2 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CRK19923.1 - 0.0025 17.5 0.1 0.0081 15.9 0.1 2.0 1 0 0 1 1 1 1 Leucine rich repeat LRR_9 PF14580.6 CRK19923.1 - 0.0059 16.1 0.1 0.011 15.2 0.1 1.5 1 0 0 1 1 1 1 Leucine-rich repeat Amnionless PF14828.6 CRK19924.1 - 4.4e-05 22.5 4.5 0.042 12.7 0.3 2.3 2 0 0 2 2 2 2 Amnionless Mid2 PF04478.12 CRK19924.1 - 0.0052 16.6 11.1 0.2 11.5 0.2 3.5 2 2 1 3 3 3 2 Mid2 like cell wall stress sensor Kelch_1 PF01344.25 CRK19924.1 - 0.006 16.1 1.9 21 4.8 0.4 3.9 3 0 0 3 3 3 0 Kelch motif Kelch_4 PF13418.6 CRK19924.1 - 0.013 15.5 5.0 23 5.1 0.0 5.1 6 0 0 6 6 6 0 Galactose oxidase, central domain NMU PF02070.15 CRK19924.1 - 0.045 13.6 0.2 5.4 7.0 0.0 2.8 2 0 0 2 2 2 0 Neuromedin U YrhC PF14143.6 CRK19924.1 - 0.057 13.5 0.4 17 5.6 0.0 2.3 2 0 0 2 2 2 0 YrhC-like protein DUF3039 PF11238.8 CRK19924.1 - 0.097 12.4 0.0 21 5.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3039) EphA2_TM PF14575.6 CRK19924.1 - 0.14 13.1 0.0 52 4.8 0.0 2.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Nitrate_red_gam PF02665.14 CRK19924.1 - 0.17 11.4 5.1 4.8 6.7 0.4 2.2 2 0 0 2 2 2 0 Nitrate reductase gamma subunit HLH PF00010.26 CRK19925.1 - 2.4e-32 110.7 3.2 4e-15 55.5 0.2 2.5 2 0 0 2 2 2 2 Helix-loop-helix DNA-binding domain Tropomyosin PF00261.20 CRK19925.1 - 0.00098 18.6 8.2 0.22 10.9 1.0 2.6 2 0 0 2 2 2 2 Tropomyosin HalX PF08663.10 CRK19925.1 - 0.0038 17.5 2.0 4 7.8 0.1 3.2 2 0 0 2 2 2 2 HalX domain DUF5553 PF17707.1 CRK19925.1 - 0.0093 15.4 0.5 1.4 8.3 0.1 2.3 2 0 0 2 2 2 2 Family of unknown function (DUF5553) Med28 PF11594.8 CRK19925.1 - 0.14 12.2 2.9 14 5.7 0.0 3.0 3 0 0 3 3 3 0 Mediator complex subunit 28 Xpo1 PF08389.12 CRK19925.1 - 4.2 7.4 7.3 31 4.6 0.6 3.4 2 2 1 3 3 3 0 Exportin 1-like protein Pcc1 PF09341.10 CRK19928.1 - 6.8e-31 106.2 1.2 8e-31 106.0 1.2 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 MlaA PF04333.13 CRK19928.1 - 0.083 12.6 0.0 0.09 12.5 0.0 1.1 1 0 0 1 1 1 0 MlaA lipoprotein DSPn PF14671.6 CRK19930.1 - 5.4e-41 140.3 0.0 1.1e-38 132.8 0.0 2.6 2 1 0 2 2 2 2 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 CRK19930.1 - 2.6e-16 59.7 0.0 5.4e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CRK19930.1 - 6.5e-06 25.9 0.0 1.3e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase ELO PF01151.18 CRK19936.1 - 3.9e-117 390.2 38.6 5.5e-62 209.5 17.4 2.0 2 0 0 2 2 2 2 GNS1/SUR4 family Rtt106 PF08512.12 CRK19936.1 - 0.0035 17.7 1.1 3.7 8.0 0.1 2.5 2 0 0 2 2 2 2 Histone chaperone Rttp106-like DUF3290 PF11694.8 CRK19936.1 - 0.027 14.4 4.2 4.3 7.3 0.3 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) Tmemb_18A PF09771.9 CRK19936.1 - 0.093 13.1 3.5 9.8 6.6 0.3 2.5 2 0 0 2 2 2 0 Transmembrane protein 188 Npa1 PF11707.8 CRK19941.1 - 1e-96 324.3 0.0 1.6e-96 323.6 0.0 1.3 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 CRK19941.1 - 1.6e-59 200.9 0.1 4.3e-59 199.5 0.1 1.8 1 0 0 1 1 1 1 Nucleolar pre-ribosomal-associated protein 1 DIM1 PF02966.16 CRK19942.1 - 1.9e-68 228.3 0.1 2.1e-68 228.2 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 CRK19942.1 - 0.03 14.3 0.0 0.038 14.0 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin MOR2-PAG1_N PF14222.6 CRK19943.1 - 1.4e-215 717.4 0.0 2.8e-215 716.5 0.0 1.5 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 CRK19943.1 - 6.3e-95 317.8 0.3 2e-94 316.2 0.3 2.0 1 0 0 1 1 1 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 CRK19943.1 - 4.6e-39 133.9 4.6 3.6e-17 61.4 0.1 3.4 2 1 1 3 3 3 3 Cell morphogenesis central region HEAT_2 PF13646.6 CRK19943.1 - 0.0074 16.7 1.7 1.2 9.5 0.1 5.0 6 0 0 6 6 6 1 HEAT repeats HEAT PF02985.22 CRK19943.1 - 0.3 11.4 0.0 0.3 11.4 0.0 4.3 5 0 0 5 5 5 0 HEAT repeat FAD_binding_1 PF00667.20 CRK19945.1 - 2.2e-61 207.3 0.0 3.4e-61 206.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 CRK19945.1 - 2.4e-32 112.1 1.5 2.4e-32 112.1 1.5 1.8 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 CRK19945.1 - 8.1e-20 71.5 0.0 6.4e-19 68.6 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 CRK19945.1 - 0.0084 16.3 0.0 0.028 14.6 0.0 2.0 1 0 0 1 1 1 1 Flavodoxin domain RRM_1 PF00076.22 CRK19946.1 - 4.4e-21 74.5 0.0 4.4e-09 36.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NUDIX PF00293.28 CRK19947.1 - 4.2e-27 94.8 0.0 6.9e-27 94.1 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain RPN1_RPN2_N PF17781.1 CRK19948.1 - 5.7e-111 370.8 2.7 8.6e-111 370.2 2.7 1.3 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 CRK19948.1 - 1.5e-29 101.8 0.0 2.7e-29 101.0 0.0 1.5 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 CRK19948.1 - 2.1e-18 65.8 16.2 5.7e-06 26.5 0.1 7.7 8 1 0 8 8 8 4 Proteasome/cyclosome repeat HEAT_2 PF13646.6 CRK19948.1 - 4.1e-08 33.5 0.4 0.019 15.3 0.0 3.9 4 1 1 5 5 5 3 HEAT repeats Herpes_UL95 PF03038.14 CRK19948.1 - 0.077 12.1 0.1 0.15 11.2 0.1 1.3 1 0 0 1 1 1 0 UL95 family IFRD PF05004.13 CRK19948.1 - 0.11 11.6 5.2 0.57 9.2 0.1 3.6 3 1 0 3 3 3 0 Interferon-related developmental regulator (IFRD) HAND PF09110.11 CRK19948.1 - 0.12 13.1 3.3 0.33 11.7 3.3 1.6 1 0 0 1 1 1 0 HAND DUF848 PF05852.11 CRK19948.1 - 0.23 11.6 1.1 0.85 9.7 0.6 2.2 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) RIO1 PF01163.22 CRK19950.1 - 4.3e-38 130.8 0.1 4.8e-26 91.5 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Rio2_N PF09202.11 CRK19950.1 - 4.1e-28 97.4 0.0 8.9e-28 96.3 0.0 1.6 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.23 CRK19950.1 - 2.4e-06 27.7 0.2 0.0043 17.0 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 CRK19950.1 - 6.2e-05 22.4 0.0 0.0016 17.8 0.0 2.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family CNDH2_C PF16858.5 CRK19950.1 - 1 9.2 5.5 1.5 8.7 5.5 1.2 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Utp14 PF04615.13 CRK19950.1 - 1.9 7.0 15.0 2.5 6.6 15.0 1.1 1 0 0 1 1 1 0 Utp14 protein Vfa1 PF08432.10 CRK19950.1 - 3.2 8.0 6.8 5.1 7.4 6.8 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Pox_Ag35 PF03286.14 CRK19950.1 - 7.8 6.2 9.3 13 5.5 9.3 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Acetyltransf_9 PF13527.7 CRK19951.1 - 1.6e-07 31.5 0.0 2.9e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CRK19951.1 - 9.7e-07 29.0 0.0 1.5e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CRK19951.1 - 7.2e-06 26.3 0.0 1.3e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CRK19951.1 - 7.7e-05 22.6 0.0 0.00012 22.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CRK19951.1 - 0.03 14.3 0.0 0.062 13.3 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein RPA_C PF08784.11 CRK19952.1 - 6.2e-23 81.4 0.5 6.2e-23 81.4 0.5 1.6 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 CRK19952.1 - 5.7e-06 26.2 0.6 1.6e-05 24.8 0.2 2.0 2 1 0 2 2 2 1 OB-fold nucleic acid binding domain Pectinesterase PF01095.19 CRK19953.1 - 3.4e-162 538.2 62.2 9.5e-46 155.9 4.7 9.1 7 2 1 8 8 8 7 Pectinesterase Pectinesterase PF01095.19 CRK19954.1 - 1.6e-34 119.0 41.3 2e-26 92.4 7.9 4.7 5 1 1 6 6 6 4 Pectinesterase Mito_carr PF00153.27 CRK19955.1 - 4.7e-15 55.3 0.2 7.9e-09 35.3 0.0 3.3 2 1 0 2 2 2 2 Mitochondrial carrier protein Asparaginase_2 PF01112.18 CRK19956.1 - 6.9e-73 245.3 7.8 1e-72 244.8 7.8 1.1 1 0 0 1 1 1 1 Asparaginase PhzC-PhzF PF02567.16 CRK19956.1 - 4.4e-18 65.7 0.0 6.4e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein ubiquitin PF00240.23 CRK19957.1 - 1.9e-70 232.6 12.8 1.6e-32 111.1 0.6 3.8 4 0 0 4 4 3 3 Ubiquitin family Rad60-SLD PF11976.8 CRK19957.1 - 1.6e-29 101.5 13.6 9.6e-15 54.2 0.7 3.7 4 0 0 4 4 3 2 Ubiquitin-2 like Rad60 SUMO-like BRAP2 PF07576.12 CRK19957.1 - 6.3e-27 93.7 0.0 1.2e-26 92.8 0.0 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 CRK19957.1 - 1.8e-17 63.4 4.1 1.8e-17 63.4 4.1 2.6 2 0 0 2 2 1 1 Zn-finger in ubiquitin-hydrolases and other protein Ubiquitin_2 PF14560.6 CRK19957.1 - 1.7e-10 41.2 3.5 0.0013 19.1 0.1 3.9 3 0 0 3 3 3 2 Ubiquitin-like domain zf-RING_2 PF13639.6 CRK19957.1 - 6.5e-08 32.8 9.8 6.5e-08 32.8 9.8 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 CRK19957.1 - 4.8e-07 29.4 5.2 1.8e-06 27.5 5.2 2.1 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 CRK19957.1 - 2.3e-06 27.3 10.2 5.5e-06 26.1 10.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TBK1_ULD PF18396.1 CRK19957.1 - 2.6e-06 27.3 0.2 0.12 12.3 0.0 2.5 2 0 0 2 2 2 2 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 CRK19957.1 - 3.3e-06 27.4 0.6 0.079 13.3 0.1 2.9 2 0 0 2 2 2 2 Ubiquitin-like domain zf-C3HC4 PF00097.25 CRK19957.1 - 2.9e-05 23.9 8.5 7.1e-05 22.6 8.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rad60-SLD_2 PF13881.6 CRK19957.1 - 3.6e-05 23.8 0.1 0.55 10.3 0.0 3.0 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like Prok-RING_4 PF14447.6 CRK19957.1 - 5.9e-05 22.8 7.9 5.9e-05 22.8 7.9 2.1 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 CRK19957.1 - 6.7e-05 22.8 3.6 0.00093 19.2 3.7 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 CRK19957.1 - 0.0003 20.7 9.4 0.0003 20.7 9.4 1.9 2 0 0 2 2 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 CRK19957.1 - 0.00075 19.7 7.8 0.0022 18.3 7.8 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 CRK19957.1 - 0.00084 19.2 7.5 0.00084 19.2 7.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF2407 PF10302.9 CRK19957.1 - 0.0013 19.2 4.4 0.97 10.0 0.0 3.2 2 2 0 3 3 3 2 DUF2407 ubiquitin-like domain zf-RING_6 PF14835.6 CRK19957.1 - 0.0078 16.1 3.6 0.0078 16.1 3.6 1.7 2 0 0 2 2 1 1 zf-RING of BARD1-type protein Ubiquitin_4 PF18036.1 CRK19957.1 - 0.23 11.5 9.2 62 3.7 0.2 5.0 5 0 0 5 5 5 0 Ubiquitin-like domain DUF4616 PF15394.6 CRK19957.1 - 0.23 10.4 5.2 0.36 9.7 5.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4616) ACT_5 PF13710.6 CRK19957.1 - 0.39 10.6 1.5 37 4.3 0.0 2.9 3 0 0 3 3 3 0 ACT domain zf-ANAPC11 PF12861.7 CRK19957.1 - 0.62 10.2 7.3 1.6 8.8 7.3 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 CRK19957.1 - 0.75 10.0 4.2 6.5 7.0 4.5 2.4 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING CSN5_C PF18323.1 CRK19957.1 - 1.2 10.1 4.9 4.2 8.4 4.9 2.1 1 0 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain Tash_PEST PF07708.11 CRK19957.1 - 7.5 6.9 9.6 20 5.5 1.4 2.6 2 0 0 2 2 2 0 Tash protein PEST motif Zn_clus PF00172.18 CRK19958.1 - 0.0019 18.3 6.9 0.0044 17.1 6.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HAUS-augmin3 PF14932.6 CRK19958.1 - 0.2 11.2 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Prenyltrans PF00432.21 CRK19961.1 - 5.5e-35 118.8 20.0 2.3e-11 43.2 0.4 6.3 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans PF00432.21 CRK19962.1 - 1.3e-35 120.8 19.3 1.6e-11 43.7 0.2 6.2 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat DND1_DSRM PF14709.7 CRK19963.1 - 0.0043 17.3 0.1 0.0075 16.5 0.1 1.5 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 dsrm PF00035.26 CRK19963.1 - 0.0049 17.5 0.0 0.011 16.5 0.0 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif NTP_transferase PF00483.23 CRK19964.1 - 2.2e-54 184.7 0.0 4.5e-54 183.7 0.0 1.5 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.24 CRK19964.1 - 3.6e-17 61.3 17.0 4.7e-10 38.8 1.8 3.4 2 2 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 CRK19964.1 - 2.4e-11 44.3 0.0 3.3e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 CRK19964.1 - 3.6e-07 29.8 4.4 3.8e-06 26.6 1.0 2.9 2 0 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 CRK19964.1 - 0.00022 19.6 0.1 0.00032 19.0 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) IspD PF01128.19 CRK19964.1 - 0.044 13.5 0.0 0.073 12.8 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CTP_transf_3 PF02348.19 CRK19964.1 - 0.093 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Cytidylyltransferase DUF1694 PF07997.11 CRK19964.1 - 0.11 12.6 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1694) FGGY_C PF02782.16 CRK19966.1 - 9.2e-105 348.6 1.8 6e-53 179.5 0.1 2.4 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 CRK19966.1 - 2.3e-51 174.7 0.4 1.4e-47 162.4 0.4 2.2 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain z-alpha PF02295.17 CRK19966.1 - 0.033 14.3 0.0 23 5.1 0.0 3.2 4 0 0 4 4 4 0 Adenosine deaminase z-alpha domain RXT2_N PF08595.11 CRK19967.1 - 5.7e-39 133.6 1.7 8.1e-39 133.2 0.1 2.2 2 1 0 2 2 2 1 RXT2-like, N-terminal DUF2963 PF11178.8 CRK19967.1 - 0.12 12.1 0.1 0.28 10.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2963) Foie-gras_1 PF11817.8 CRK19968.1 - 1.4e-44 152.6 1.4 1.3e-38 133.0 2.2 2.2 2 0 0 2 2 2 2 Foie gras liver health family 1 DUF5576 PF17739.1 CRK19968.1 - 0.15 12.1 0.1 2.1 8.5 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5576) RXT2_N PF08595.11 CRK19969.1 - 3e-39 134.6 2.8 5.3e-39 133.7 0.1 2.5 2 1 0 2 2 2 1 RXT2-like, N-terminal Gryzun PF07919.12 CRK19970.1 - 1.2e-234 780.6 0.0 1.4e-234 780.3 0.0 1.0 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.8 CRK19970.1 - 2.5e-46 158.4 0.4 3.6e-46 157.9 0.4 1.2 1 0 0 1 1 1 1 Foie gras liver health family 1 Gryzun-like PF12742.7 CRK19970.1 - 2.6e-05 24.1 0.0 4.8e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking Abhydrolase_6 PF12697.7 CRK19971.1 - 1.2e-12 48.9 12.5 2.2e-12 48.0 12.5 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CRK19971.1 - 4.9e-05 23.1 0.1 0.00051 19.8 0.0 2.2 2 1 1 3 3 3 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CRK19971.1 - 0.00043 19.6 0.0 0.00073 18.9 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 CRK19971.1 - 0.14 11.0 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Bac_rhamnosid6H PF17389.2 CRK19972.1 - 2.8e-54 184.7 0.1 5.8e-37 127.7 0.5 2.3 1 1 1 2 2 2 2 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 CRK19972.1 - 4.3e-29 101.5 0.2 4.4e-16 59.2 0.0 2.4 2 0 0 2 2 2 2 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid PF05592.11 CRK19972.1 - 5.4e-19 68.1 0.0 1.1e-18 67.1 0.0 1.5 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Bac_rhamnosid_C PF17390.2 CRK19972.1 - 4.2e-13 48.9 0.0 1.2e-12 47.4 0.0 1.8 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Piwi PF02171.17 CRK19974.1 - 5.2e-69 232.8 0.0 7.8e-69 232.2 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoL1 PF08699.10 CRK19974.1 - 1.4e-21 75.9 2.5 1.3e-09 37.6 0.2 2.7 2 0 0 2 2 2 2 Argonaute linker 1 domain ArgoN PF16486.5 CRK19974.1 - 1.4e-13 51.6 1.7 3.6e-08 34.1 0.2 3.3 3 0 0 3 3 3 2 N-terminal domain of argonaute ArgoL2 PF16488.5 CRK19974.1 - 4.6e-09 36.5 0.0 1.1e-08 35.3 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain 4HBT_2 PF13279.6 CRK19974.1 - 0.001 19.6 0.0 1.4 9.4 0.0 3.4 3 0 0 3 3 3 1 Thioesterase-like superfamily ArgoMid PF16487.5 CRK19974.1 - 0.0012 19.1 0.0 0.0031 17.7 0.0 1.7 1 0 0 1 1 1 1 Mid domain of argonaute Inositol_P PF00459.25 CRK19974.1 - 0.063 12.8 0.0 8.2 5.9 0.0 2.3 2 0 0 2 2 2 0 Inositol monophosphatase family Glyco_hydro81C PF17652.1 CRK19975.1 - 2.7e-164 546.5 4.6 3.8e-164 546.0 4.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 CRK19975.1 - 1.3e-115 386.0 0.1 1.9e-115 385.4 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain DnaJ PF00226.31 CRK19975.1 - 1.3e-21 76.5 1.8 2.7e-21 75.5 1.8 1.6 1 0 0 1 1 1 1 DnaJ domain Stn1 PF10451.9 CRK19975.1 - 2.6e-10 39.7 2.0 1.5e-05 24.1 0.1 2.3 2 0 0 2 2 2 2 Telomere regulation protein Stn1 PaaB PF06243.11 CRK19975.1 - 0.073 13.3 0.6 0.2 11.9 0.6 1.7 1 0 0 1 1 1 0 Phenylacetic acid degradation B D5_N PF08706.11 CRK19975.1 - 7.3 6.8 6.2 4.9 7.4 0.5 2.8 2 0 0 2 2 2 0 D5 N terminal like Glyco_hydro81C PF17652.1 CRK19977.1 - 1.6e-113 379.5 2.7 2.6e-113 378.8 2.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 CRK19977.1 - 2.8e-52 177.9 0.1 5e-52 177.1 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Na_Ca_ex PF01699.24 CRK19977.1 - 4.8e-33 114.2 26.2 1.2e-23 83.7 13.7 3.3 3 0 0 3 3 3 3 Sodium/calcium exchanger protein DUF202 PF02656.15 CRK19977.1 - 4.3 7.9 5.7 6.8 7.2 0.1 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF202) Utp14 PF04615.13 CRK19979.1 - 7.4e-88 296.0 16.9 1e-87 295.5 16.9 1.2 1 0 0 1 1 1 1 Utp14 protein DivIC PF04977.15 CRK19979.1 - 3.1 7.6 6.5 0.29 10.9 1.6 1.8 2 0 0 2 2 2 0 Septum formation initiator Na_Ca_ex PF01699.24 CRK19981.1 - 2.9e-43 147.4 30.0 7.8e-23 81.1 10.3 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Utp14 PF04615.13 CRK19983.1 - 5.5e-187 623.8 68.4 5.5e-187 623.8 68.4 2.2 1 1 1 2 2 2 1 Utp14 protein DivIC PF04977.15 CRK19983.1 - 1.5 8.6 14.8 0.24 11.2 1.4 3.1 2 0 0 2 2 2 0 Septum formation initiator COX15-CtaA PF02628.15 CRK19984.1 - 5.7e-112 374.0 9.1 7e-112 373.7 9.1 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein tRNA-synt_2 PF00152.20 CRK19986.1 - 4.7e-19 68.6 0.0 6.2e-19 68.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 CRK19986.1 - 0.017 14.6 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.20 CRK19988.1 - 2.7e-63 213.9 1.8 7.8e-63 212.4 1.8 1.7 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CRK19988.1 - 1.5e-10 40.9 0.1 3.1e-10 39.9 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CRK19988.1 - 1.8e-06 27.6 0.3 0.016 14.7 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Furin-like_2 PF15913.5 CRK19988.1 - 0.086 13.0 0.0 16 5.7 0.0 2.7 3 0 0 3 3 3 0 Furin-like repeat, cysteine-rich Acyltransferase PF01553.21 CRK19990.1 - 1.3e-21 76.6 0.0 1.2e-08 34.6 0.0 3.9 2 2 0 2 2 2 2 Acyltransferase Suc_Fer-like PF06999.12 CRK19992.1 - 1.9e-08 34.5 0.0 2.1e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Suc_Fer-like PF06999.12 CRK19994.1 - 2.2e-70 236.5 0.0 2.6e-70 236.3 0.0 1.0 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Ribosomal_60s PF00428.19 CRK19994.1 - 9.2 6.9 8.0 0.42 11.2 1.9 1.9 3 0 0 3 3 3 0 60s Acidic ribosomal protein ESCRT-II PF05871.12 CRK19996.1 - 3.6e-59 199.0 0.0 4.6e-59 198.7 0.0 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit RTT107_BRCT_5 PF16770.5 CRK19998.1 - 2.3e-30 104.4 0.0 4.7e-27 93.8 0.0 3.6 3 0 0 3 3 3 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT PF00533.26 CRK19998.1 - 2.5e-29 101.5 0.0 2e-11 44.1 0.0 6.5 7 1 0 7 7 7 4 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 CRK19998.1 - 4.8e-29 100.1 0.8 6.1e-21 74.1 0.3 4.7 5 0 0 5 5 5 3 twin BRCT domain BRCT_2 PF16589.5 CRK19998.1 - 3.7e-21 75.3 0.0 2.8e-05 24.4 0.1 5.2 5 0 0 5 5 5 4 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 CRK19998.1 - 6.3e-09 36.0 0.1 0.29 11.4 0.0 3.6 3 0 0 3 3 3 3 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 CRK19998.1 - 0.00033 20.7 0.1 0.075 13.1 0.0 3.6 4 0 0 4 4 4 1 BRCA1 C Terminus (BRCT) domain adh_short PF00106.25 CRK20001.1 - 0.0033 16.9 0.0 2.3 7.6 0.0 3.3 3 0 0 3 3 3 3 short chain dehydrogenase MFS_1 PF07690.16 CRK20002.1 - 1.2e-10 40.9 31.4 1e-08 34.6 18.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_115 PF15979.5 CRK20006.1 - 1.8e-131 438.6 0.1 2.4e-131 438.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 CRK20006.1 - 1.3e-40 139.0 0.0 2.3e-40 138.2 0.0 1.4 1 0 0 1 1 1 1 Gylcosyl hydrolase family 115 C-terminal domain UCR_hinge PF02320.16 CRK20006.1 - 2.6e-11 43.5 8.2 5.5e-11 42.5 6.5 2.2 2 0 0 2 2 2 1 Ubiquinol-cytochrome C reductase hinge protein RR_TM4-6 PF06459.12 CRK20006.1 - 1.4 8.7 19.6 3 7.6 15.4 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DUF5523 PF17661.1 CRK20006.1 - 2.1 7.9 18.7 3.6 7.2 18.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5523) BUD22 PF09073.10 CRK20006.1 - 4.4 6.5 21.1 6.4 6.0 21.1 1.1 1 0 0 1 1 1 0 BUD22 RraA-like PF03737.15 CRK20009.1 - 8.5e-27 94.2 0.2 1.1e-26 93.8 0.2 1.1 1 0 0 1 1 1 1 Aldolase/RraA Drf_GBD PF06371.13 CRK20011.1 - 4.3e-14 52.5 0.3 1.1e-08 34.9 0.0 2.4 2 0 0 2 2 2 2 Diaphanous GTPase-binding Domain Nop14 PF04147.12 CRK20013.1 - 3.4e-278 925.6 32.3 3.4e-278 925.6 32.3 3.2 3 1 0 3 3 3 1 Nop14-like family DEAD PF00270.29 CRK20013.1 - 2.2e-20 73.2 0.0 6.9e-20 71.5 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 CRK20013.1 - 2.3e-18 66.7 4.7 1.1e-17 64.5 4.7 2.3 1 0 0 1 1 1 1 RecQ zinc-binding Helicase_C PF00271.31 CRK20013.1 - 4.1e-17 62.5 0.0 2.7e-16 59.9 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RQC PF09382.10 CRK20013.1 - 9.5e-12 44.7 0.2 3.6e-11 42.8 0.1 2.0 2 0 0 2 2 2 1 RQC domain ResIII PF04851.15 CRK20013.1 - 1.3e-05 25.3 0.0 0.00024 21.1 0.0 3.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HRDC PF00570.23 CRK20013.1 - 0.00022 21.2 0.1 0.00022 21.2 0.1 3.2 3 0 0 3 3 3 1 HRDC domain Polysacc_synt_3 PF13440.6 CRK20013.1 - 0.23 10.6 0.0 0.52 9.5 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Pkinase PF00069.25 CRK20017.1 - 9.9e-30 103.8 0.0 1.1e-17 64.3 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain CAP_GLY PF01302.25 CRK20017.1 - 4.6e-16 58.6 0.9 8.4e-16 57.7 0.2 1.8 2 0 0 2 2 2 1 CAP-Gly domain Pkinase_Tyr PF07714.17 CRK20017.1 - 8.1e-09 35.1 0.0 8.5e-07 28.5 0.0 2.8 2 1 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 CRK20017.1 - 1.1e-05 25.5 0.0 1.1e-05 25.5 0.0 3.1 3 1 0 3 3 2 1 Phosphotransferase enzyme family Abhydrolase_6 PF12697.7 CRK20017.1 - 6.9e-05 23.5 1.3 6.9e-05 23.5 1.3 2.7 2 1 1 3 3 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CRK20017.1 - 0.0002 21.1 0.2 0.00067 19.4 0.1 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold AAA_13 PF13166.6 CRK20017.1 - 0.0021 16.8 8.5 0.0021 16.8 8.5 1.8 1 1 0 1 1 1 1 AAA domain Oxysterol_BP PF01237.18 CRK20017.1 - 0.0032 16.4 0.2 0.0055 15.6 0.2 1.2 1 0 0 1 1 1 1 Oxysterol-binding protein DUF3349 PF11829.8 CRK20017.1 - 1.3 9.9 3.8 1.4 9.8 1.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) sCache_like PF16736.5 CRK20017.1 - 1.9 8.6 4.1 22 5.2 0.1 2.4 2 0 0 2 2 2 0 Single Cache-like Sec2p PF06428.11 CRK20017.1 - 2.2 8.3 19.1 0.72 9.9 1.8 3.8 4 0 0 4 4 4 0 GDP/GTP exchange factor Sec2p NPV_P10 PF05531.12 CRK20017.1 - 2.4 8.7 6.2 5.2 7.6 0.3 2.9 3 0 0 3 3 2 0 Nucleopolyhedrovirus P10 protein Med4 PF10018.9 CRK20017.1 - 2.6 7.7 16.5 0.73 9.5 1.4 2.9 3 0 0 3 3 3 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF812 PF05667.11 CRK20017.1 - 4.2 6.1 28.7 2.8 6.7 15.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Glutaredoxin2_C PF04399.13 CRK20017.1 - 4.5 7.1 6.5 11 5.8 0.2 3.1 3 0 0 3 3 3 0 Glutaredoxin 2, C terminal domain DUF241 PF03087.14 CRK20017.1 - 5.3 6.8 9.2 0.14 12.0 1.4 2.3 3 0 0 3 3 3 0 Arabidopsis protein of unknown function CLIP1_ZNF PF16641.5 CRK20017.1 - 6.9 6.7 6.9 0.8 9.7 2.2 1.9 2 0 0 2 2 2 0 CLIP1 zinc knuckle BLOC1_2 PF10046.9 CRK20017.1 - 8.7 6.7 17.4 0.66 10.3 2.2 3.5 4 0 0 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Glyco_hydro_38N PF01074.22 CRK20020.1 - 7.7e-87 291.3 3.1 1.3e-86 290.6 3.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 CRK20020.1 - 1.3e-54 185.5 0.6 2.8e-53 181.1 0.0 2.6 3 0 0 3 3 3 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 CRK20020.1 - 1.5e-26 92.4 0.0 3.6e-26 91.1 0.0 1.7 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 CRK20020.1 - 1.5e-09 37.9 0.1 1.2e-08 35.0 0.0 2.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Ribosomal_L10 PF00466.20 CRK20021.1 - 1.8e-22 79.3 0.0 4.4e-22 78.1 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L10 RL10P_insert PF17777.1 CRK20021.1 - 3.1e-22 78.3 0.0 6.3e-22 77.4 0.0 1.5 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 CRK20021.1 - 5.9e-18 65.2 3.6 5.9e-18 65.2 3.6 2.1 2 0 0 2 2 2 1 60s Acidic ribosomal protein VirE_N PF08800.10 CRK20021.1 - 0.036 14.2 0.0 0.067 13.3 0.0 1.4 1 0 0 1 1 1 0 VirE N-terminal domain CPSF_A PF03178.15 CRK20023.1 - 0.045 13.1 0.0 3.7 6.8 0.0 2.5 1 1 1 2 2 2 0 CPSF A subunit region DnaJ_C PF01556.18 CRK20024.1 - 9e-37 126.4 0.1 1.2e-36 126.0 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CRK20024.1 - 9.2e-27 93.0 2.8 1.6e-26 92.2 2.8 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CRK20024.1 - 1.8e-15 57.0 18.8 3.7e-15 56.0 18.8 1.6 1 0 0 1 1 1 1 DnaJ central domain zinc-ribbons_6 PF07191.12 CRK20024.1 - 0.25 11.4 6.5 4.3 7.4 1.4 2.6 2 0 0 2 2 2 0 zinc-ribbons DUF2614 PF11023.8 CRK20024.1 - 0.5 10.5 6.3 4.2 7.5 1.0 2.2 1 1 1 2 2 2 0 Zinc-ribbon containing domain HypA PF01155.19 CRK20024.1 - 0.69 9.9 10.2 1.8 8.6 2.6 2.5 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 CRK20024.1 - 1.6 8.7 17.5 2.2 8.3 3.3 2.8 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein Zn_Tnp_IS1595 PF12760.7 CRK20024.1 - 4.9 7.2 10.6 3.2 7.8 2.6 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Asp PF00026.23 CRK20026.1 - 8.5e-33 114.1 0.0 1.3e-32 113.5 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease adh_short_C2 PF13561.6 CRK20026.1 - 4.7e-30 104.9 0.0 1.4e-29 103.4 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRK20026.1 - 2.8e-24 85.6 0.0 4.6e-24 85.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase TAXi_N PF14543.6 CRK20026.1 - 8e-08 32.7 0.0 3.3e-06 27.4 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal KR PF08659.10 CRK20026.1 - 1.3e-07 31.7 0.0 3.5e-07 30.3 0.0 1.6 2 0 0 2 2 2 1 KR domain Asp_protease_2 PF13650.6 CRK20026.1 - 0.019 15.6 0.3 13 6.5 0.0 3.3 3 1 0 3 3 3 0 Aspartyl protease ETF PF01012.21 CRK20026.1 - 0.15 11.9 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 Electron transfer flavoprotein domain DEAD PF00270.29 CRK20028.1 - 2.7e-33 115.2 0.9 5.9e-32 110.8 0.9 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CRK20028.1 - 1.2e-31 109.3 0.2 1.6e-30 105.7 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CRK20028.1 - 0.0014 18.7 0.0 0.002 18.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 CRK20028.1 - 0.0023 17.7 0.2 0.0038 17.0 0.2 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CRK20028.1 - 0.0056 17.0 1.1 0.026 14.9 0.5 2.2 2 1 0 2 2 2 1 AAA domain IL17R_D_N PF16742.5 CRK20028.1 - 0.013 15.6 0.0 0.031 14.3 0.0 1.6 1 0 0 1 1 1 0 N-terminus of interleukin 17 receptor D fragilysinNterm PF16376.5 CRK20028.1 - 0.084 12.6 0.1 0.26 11.0 0.0 1.8 2 0 0 2 2 2 0 N-terminal domain of fragilysin tRNA-synt_1b PF00579.25 CRK20028.1 - 0.1 11.9 0.1 0.66 9.2 0.0 2.2 3 0 0 3 3 3 0 tRNA synthetases class I (W and Y) Flavi_DEAD PF07652.14 CRK20028.1 - 0.14 12.2 0.0 0.41 10.6 0.0 1.9 2 0 0 2 2 2 0 Flavivirus DEAD domain Cupin_8 PF13621.6 CRK20029.1 - 2.6e-18 66.7 0.3 4.3e-17 62.7 0.3 2.3 1 1 0 1 1 1 1 Cupin-like domain DUF1771 PF08590.10 CRK20029.1 - 4.7e-15 55.7 11.6 1.2e-14 54.4 11.6 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) JmjC PF02373.22 CRK20029.1 - 1.5e-11 44.7 0.1 3.8e-11 43.4 0.1 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf_CCCH_4 PF18345.1 CRK20029.1 - 5.4e-08 32.6 8.8 6.3e-06 26.1 0.6 3.3 2 1 0 2 2 2 2 Zinc finger domain Smr PF01713.21 CRK20029.1 - 2.9e-07 30.7 0.0 8.3e-07 29.3 0.0 1.8 1 0 0 1 1 1 1 Smr domain zf-CCCH PF00642.24 CRK20029.1 - 1.6e-06 27.9 3.5 0.0013 18.6 0.4 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CRK20029.1 - 0.002 17.9 0.4 0.002 17.9 0.4 3.4 3 1 0 3 3 3 1 CCCH-type zinc finger F-box-like PF12937.7 CRK20029.1 - 0.003 17.4 0.2 0.0071 16.2 0.2 1.7 1 0 0 1 1 1 1 F-box-like zf-CCCH_2 PF14608.6 CRK20029.1 - 0.0032 17.9 9.2 0.16 12.5 0.9 3.0 3 0 0 3 3 3 2 RNA-binding, Nab2-type zinc finger Glyco_transf_90 PF05686.12 CRK20029.1 - 0.036 13.0 0.1 0.063 12.2 0.1 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 90 Cupin_4 PF08007.12 CRK20029.1 - 0.1 12.1 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 Cupin superfamily protein zf-CCCH_3 PF15663.5 CRK20029.1 - 0.44 10.8 4.5 5.5 7.2 0.2 2.7 2 1 1 3 3 2 0 Zinc-finger containing family Torus PF16131.5 CRK20029.1 - 6 7.6 5.8 3.1 8.5 0.8 2.4 1 1 1 2 2 2 0 Torus domain DUF1771 PF08590.10 CRK20031.1 - 1.9e-15 57.0 11.6 1.9e-15 57.0 11.6 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.21 CRK20031.1 - 4.4e-08 33.4 0.0 1.2e-07 32.0 0.0 1.7 1 0 0 1 1 1 1 Smr domain RuvX PF03652.15 CRK20032.1 - 4.5 7.7 7.7 11 6.4 1.1 2.5 2 0 0 2 2 2 0 Holliday junction resolvase HTH_AsnC-type PF13404.6 CRK20033.1 - 0.12 12.2 0.3 0.3 11.0 0.3 1.6 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Abhydrolase_1 PF00561.20 CRK20034.1 - 8.1e-12 45.3 0.0 1.3e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CRK20034.1 - 9.7e-08 31.6 0.0 2.4e-07 30.3 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CRK20034.1 - 0.003 18.2 11.0 0.088 13.4 11.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 CRK20034.1 - 0.0089 15.7 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Peptidase_S28 PF05577.12 CRK20034.1 - 0.11 11.2 0.0 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Peptidase_S9 PF00326.21 CRK20034.1 - 0.13 11.7 0.0 0.42 10.0 0.0 1.9 1 1 0 1 1 1 0 Prolyl oligopeptidase family Helicase_C PF00271.31 CRK20035.1 - 1.5e-06 28.5 0.0 7.6e-06 26.2 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HHH_5 PF14520.6 CRK20035.1 - 0.00037 21.1 0.0 0.19 12.4 0.0 2.6 2 0 0 2 2 2 2 Helix-hairpin-helix domain DUF4332 PF14229.6 CRK20035.1 - 0.064 13.5 0.1 0.8 10.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4332) SRP19 PF01922.17 CRK20035.1 - 0.071 14.1 0.2 26 5.9 0.0 2.5 2 0 0 2 2 2 0 SRP19 protein Pox_L5 PF04872.13 CRK20035.1 - 0.17 11.8 0.2 0.42 10.5 0.1 1.7 2 0 0 2 2 2 0 Poxvirus L5 protein family Adenylsucc_synt PF00709.21 CRK20036.1 - 7.3e-145 483.1 1.2 7.2e-143 476.5 0.0 2.0 2 0 0 2 2 2 2 Adenylosuccinate synthetase Regnase_1_C PF18561.1 CRK20036.1 - 0.16 11.7 0.0 0.38 10.5 0.0 1.6 1 0 0 1 1 1 0 Endoribonuclease Regnase 1/ ZC3H12 C-terminal domain BAH PF01426.18 CRK20039.1 - 3.1e-34 117.5 0.1 1.2e-15 57.4 0.0 2.5 2 0 0 2 2 2 2 BAH domain PHD PF00628.29 CRK20039.1 - 4.3e-18 65.0 49.9 2.1e-06 27.5 8.6 5.0 5 0 0 5 5 5 3 PHD-finger PHD_2 PF13831.6 CRK20039.1 - 7.8e-09 34.9 4.4 7.8e-09 34.9 4.4 5.8 7 0 0 7 7 7 3 PHD-finger DNA_binding_2 PF13724.6 CRK20039.1 - 8.8e-06 26.0 3.8 0.18 12.2 0.3 3.8 2 0 0 2 2 2 2 DNA-binding domain ELM2 PF01448.24 CRK20039.1 - 8.5e-05 23.2 1.4 0.76 10.6 0.1 3.7 2 0 0 2 2 2 2 ELM2 domain TrkA_C PF02080.21 CRK20039.1 - 0.001 18.8 0.1 2.4 8.0 0.0 2.4 2 0 0 2 2 2 2 TrkA-C domain C1_1 PF00130.22 CRK20039.1 - 0.091 12.7 44.6 0.014 15.3 3.2 5.8 5 1 1 6 6 6 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RhoGAP PF00620.27 CRK20041.1 - 7e-34 116.8 0.0 1.4e-33 115.9 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 CRK20041.1 - 5.1e-30 103.5 38.5 1.7e-11 44.1 5.4 4.8 5 0 0 5 5 5 4 LIM domain Desulfoferrod_N PF06397.12 CRK20041.1 - 3.1 7.5 6.5 0.54 9.9 0.1 2.9 3 0 0 3 3 3 0 Desulfoferrodoxin, N-terminal domain NinD PF17466.2 CRK20041.1 - 9.6 6.4 10.8 0.35 11.0 1.7 3.0 3 0 0 3 3 3 0 Family of unknown function 3Beta_HSD PF01073.19 CRK20042.1 - 6.4e-64 215.6 0.0 7.8e-64 215.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 CRK20042.1 - 1.2e-33 116.6 0.1 1.7e-33 116.1 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CRK20042.1 - 1e-18 67.8 0.0 1.8e-17 63.8 0.0 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 CRK20042.1 - 5.3e-17 61.8 0.1 6.7e-17 61.5 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 CRK20042.1 - 9.6e-13 47.9 0.3 2.2e-10 40.2 0.3 2.2 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 CRK20042.1 - 1.7e-12 47.6 0.4 2.5e-12 47.1 0.4 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 CRK20042.1 - 1.3e-09 37.6 0.1 4.5e-09 35.9 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 CRK20042.1 - 0.00051 20.0 0.9 0.0022 17.9 0.9 2.0 1 1 0 1 1 1 1 KR domain NAD_binding_3 PF03447.16 CRK20042.1 - 0.027 15.1 0.0 0.066 13.9 0.0 1.7 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain DUF2243 PF10002.9 CRK20042.1 - 0.028 14.6 0.1 0.1 12.7 0.1 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2243) HMG_box PF00505.19 CRK20043.1 - 7.9e-06 26.2 1.2 7.9e-06 26.2 1.2 3.5 3 1 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 CRK20043.1 - 3.5e-05 24.3 0.1 3.5e-05 24.3 0.1 2.9 3 0 0 3 3 3 1 HMG-box domain T2SSF PF00482.23 CRK20043.1 - 0.085 12.8 0.1 2.3 8.2 0.0 2.3 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F PTSIIB_sorb PF03830.15 CRK20043.1 - 1.1 9.4 5.8 0.51 10.6 2.6 2.0 2 1 0 2 2 2 0 PTS system sorbose subfamily IIB component Translin PF01997.16 CRK20043.1 - 5.4 6.9 9.1 0.49 10.3 0.2 2.6 3 0 0 3 3 3 0 Translin family NR_Repeat PF14046.6 CRK20044.1 - 0.1 12.7 0.0 4 7.7 0.0 2.2 2 0 0 2 2 2 0 Nuclear receptor repeat Proteasome PF00227.26 CRK20045.1 - 2.7e-25 89.0 0.1 8.8e-13 48.2 0.0 2.1 2 0 0 2 2 2 2 Proteasome subunit Integrase_Zn PF02022.19 CRK20045.1 - 0.23 11.5 0.1 0.44 10.6 0.1 1.5 1 0 0 1 1 1 0 Integrase Zinc binding domain SIS PF01380.22 CRK20046.1 - 1.3e-49 167.3 0.3 5.9e-32 110.3 0.1 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 CRK20046.1 - 3.9e-18 65.9 0.0 7.8e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 CRK20046.1 - 4.7e-11 42.7 0.0 1.7e-10 40.8 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_4 PF13230.6 CRK20046.1 - 0.0011 17.9 0.0 0.0018 17.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.6 CRK20046.1 - 0.046 13.8 0.0 1.3 9.0 0.0 2.6 2 1 0 2 2 2 0 SIS domain AAA PF00004.29 CRK20047.1 - 1.1e-42 145.6 0.0 2e-42 144.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 CRK20047.1 - 2.7e-11 43.3 0.0 1.8e-10 40.6 0.0 2.2 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 CRK20047.1 - 1.1e-09 37.9 0.1 2.1e-09 37.0 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 CRK20047.1 - 5.8e-07 30.1 1.1 0.00015 22.2 0.1 3.2 2 2 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 CRK20047.1 - 7.4e-06 26.2 0.0 2e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 CRK20047.1 - 1.1e-05 25.4 0.1 0.00015 21.8 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CRK20047.1 - 1.4e-05 24.9 0.0 3.2e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 CRK20047.1 - 0.00074 18.7 0.0 0.0016 17.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 CRK20047.1 - 0.0012 19.2 0.8 0.012 15.9 0.0 2.5 2 1 1 3 3 2 1 AAA domain AAA_18 PF13238.6 CRK20047.1 - 0.0022 18.6 0.0 0.0068 17.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 CRK20047.1 - 0.0029 16.9 0.0 0.0055 15.9 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_7 PF12775.7 CRK20047.1 - 0.0033 17.0 0.0 0.0063 16.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_11 PF13086.6 CRK20047.1 - 0.0048 16.7 2.3 0.61 9.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 CRK20047.1 - 0.0088 15.4 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 CRK20047.1 - 0.011 16.1 0.0 0.024 15.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 CRK20047.1 - 0.012 15.8 0.0 0.038 14.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 CRK20047.1 - 0.012 15.6 0.0 0.03 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Prot_ATP_OB_N PF17758.1 CRK20047.1 - 0.014 15.0 0.0 0.042 13.5 0.0 1.7 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain TsaE PF02367.17 CRK20047.1 - 0.016 15.2 0.0 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Tektin PF03148.14 CRK20047.1 - 0.017 13.9 1.4 0.036 12.8 1.4 1.5 1 0 0 1 1 1 0 Tektin family IstB_IS21 PF01695.17 CRK20047.1 - 0.018 14.8 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_3 PF07726.11 CRK20047.1 - 0.022 14.6 0.0 0.048 13.5 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CRK20047.1 - 0.028 14.1 0.0 0.074 12.8 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.6 CRK20047.1 - 0.059 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 CRK20047.1 - 0.063 12.6 0.3 0.29 10.5 0.0 2.2 2 0 0 2 2 2 0 KaiC AAA_30 PF13604.6 CRK20047.1 - 0.12 12.1 0.3 0.41 10.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 CRK20047.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein eIF-1a PF01176.19 CRK20047.1 - 0.13 12.0 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 NACHT PF05729.12 CRK20047.1 - 0.13 12.1 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 NACHT domain DUF4140 PF13600.6 CRK20047.1 - 0.18 12.2 5.5 1.7 9.1 1.5 2.7 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF4200 PF13863.6 CRK20047.1 - 0.19 12.1 8.8 0.034 14.6 3.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF3408 PF11888.8 CRK20047.1 - 0.36 10.9 2.7 0.72 10.0 2.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Alg6_Alg8 PF03155.15 CRK20049.1 - 5.1e-126 421.5 23.3 1.5e-77 261.6 10.9 2.1 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family OGG_N PF07934.12 CRK20049.1 - 3.4e-35 120.8 0.0 5.8e-35 120.0 0.0 1.4 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 CRK20049.1 - 7.9e-16 58.5 0.0 1.6e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 CRK20049.1 - 0.0099 15.7 0.0 0.026 14.4 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif HEAT_2 PF13646.6 CRK20050.1 - 1.2e-12 48.0 4.3 0.067 13.6 0.0 7.4 6 2 2 8 8 8 3 HEAT repeats HEAT_EZ PF13513.6 CRK20050.1 - 1.2e-12 48.0 4.4 0.0097 16.4 0.0 8.1 7 2 1 8 8 8 2 HEAT-like repeat HEAT PF02985.22 CRK20050.1 - 2.5e-09 36.6 11.5 0.062 13.6 0.1 8.5 11 0 0 11 11 11 3 HEAT repeat Cnd1 PF12717.7 CRK20050.1 - 4e-07 30.2 2.6 0.14 12.2 0.0 6.0 6 1 0 6 6 6 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 CRK20050.1 - 2.2e-06 28.2 0.7 0.87 10.2 0.0 5.6 5 1 1 6 6 6 1 Vacuolar 14 Fab1-binding region DUF3385 PF11865.8 CRK20050.1 - 0.0001 22.3 1.2 0.013 15.4 0.1 4.7 3 2 0 3 3 3 1 Domain of unknown function (DUF3385) NUC173 PF08161.12 CRK20050.1 - 0.00012 21.8 0.8 1.3 8.7 0.0 4.5 4 2 1 5 5 5 2 NUC173 domain Dopey_N PF04118.14 CRK20050.1 - 0.00028 20.1 0.6 5.7 6.0 0.0 4.5 4 1 0 5 5 5 1 Dopey, N-terminal Adaptin_N PF01602.20 CRK20050.1 - 0.0003 19.5 1.5 0.036 12.6 0.0 3.6 3 2 1 4 4 4 1 Adaptin N terminal region UNC45-central PF11701.8 CRK20050.1 - 0.00037 20.5 0.0 0.0015 18.5 0.0 2.0 2 0 0 2 2 2 1 Myosin-binding striated muscle assembly central DRIM PF07539.12 CRK20050.1 - 0.0053 15.1 0.7 4 5.6 0.0 3.9 2 2 3 5 5 5 2 Down-regulated in metastasis MMS19_C PF12460.8 CRK20050.1 - 0.022 13.9 0.0 3.2 6.8 0.0 3.2 3 1 1 4 4 4 0 RNAPII transcription regulator C-terminal WD40 PF00400.32 CRK20051.1 - 7.4e-30 102.6 20.5 2.5e-06 28.1 0.3 8.8 9 1 0 9 9 9 6 WD domain, G-beta repeat Utp12 PF04003.12 CRK20051.1 - 7.2e-20 71.3 0.4 1.4e-19 70.4 0.4 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family LSM PF01423.22 CRK20051.1 - 1e-16 60.4 0.4 2.3e-16 59.2 0.4 1.7 1 0 0 1 1 1 1 LSM domain ANAPC4_WD40 PF12894.7 CRK20051.1 - 3.5e-10 40.0 6.3 0.024 14.9 0.0 6.6 4 2 3 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CRK20051.1 - 0.00057 18.9 0.3 1.5 7.7 0.0 3.9 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CRK20051.1 - 0.0011 17.7 0.6 0.23 10.0 0.0 3.6 3 1 0 3 3 3 1 Nucleoporin Nup120/160 eIF2A PF08662.11 CRK20051.1 - 0.012 15.5 0.1 1.1 9.1 0.0 3.3 3 1 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.11 CRK20051.1 - 0.015 14.0 0.2 0.82 8.3 0.0 3.2 2 2 1 3 3 3 0 Nup133 N terminal like WD40_like PF17005.5 CRK20051.1 - 0.049 13.0 0.0 4.8 6.4 0.0 2.3 2 0 0 2 2 2 0 WD40-like domain Hfq PF17209.3 CRK20051.1 - 0.11 12.1 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 Hfq protein P34-Arc PF04045.14 CRK20052.1 - 8.2e-105 349.8 1.4 1e-104 349.5 1.4 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc ARPC4 PF05856.12 CRK20052.1 - 0.087 12.4 0.1 0.62 9.7 0.0 2.1 2 0 0 2 2 2 0 ARP2/3 complex 20 kDa subunit (ARPC4) Pertactin PF03212.14 CRK20053.1 - 0.042 13.8 0.2 0.13 12.2 0.2 1.8 1 0 0 1 1 1 0 Pertactin DUF756 PF05506.12 CRK20053.1 - 0.1 13.5 1.0 1.1 10.3 0.6 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF756) Invasin_D3 PF09134.10 CRK20053.1 - 0.19 12.1 5.0 2.7 8.3 1.4 2.6 2 0 0 2 2 2 0 Invasin, domain 3 Rax2 PF12768.7 CRK20054.1 - 1.4e-60 204.4 0.1 1.4e-60 204.4 0.1 3.7 5 0 0 5 5 5 1 Cortical protein marker for cell polarity DRMBL PF07522.14 CRK20055.1 - 9.6e-35 119.1 0.0 1.8e-34 118.2 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 CRK20055.1 - 0.00011 21.8 0.0 0.00022 20.8 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain GRA6 PF05084.13 CRK20055.1 - 0.11 12.4 1.5 0.21 11.6 1.5 1.4 1 0 0 1 1 1 0 Granule antigen protein (GRA6) zf-C2H2 PF00096.26 CRK20056.1 - 1.3e-09 38.0 11.5 2.6e-05 24.4 4.5 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CRK20056.1 - 4.5e-09 36.3 13.8 5.6e-05 23.4 0.5 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 CRK20056.1 - 1.3e-06 28.7 11.1 0.0015 19.2 3.2 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 CRK20056.1 - 8e-06 26.1 1.3 2.1e-05 24.7 1.3 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 CRK20056.1 - 0.00014 21.8 2.4 0.00014 21.8 2.4 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CRK20056.1 - 0.00087 19.5 1.8 0.00087 19.5 1.8 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 CRK20056.1 - 0.049 14.0 2.5 0.053 13.9 0.9 1.7 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.6 CRK20056.1 - 0.27 11.2 5.3 3.4 7.7 0.4 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 CRK20056.1 - 0.86 9.4 8.3 8.2 6.3 1.2 2.8 2 0 0 2 2 2 0 zinc-finger C2H2-type NUP214 PF16755.5 CRK20058.1 - 4.5e-09 36.0 0.0 3.2e-08 33.2 0.0 2.0 1 1 0 1 1 1 1 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 ANAPC4_WD40 PF12894.7 CRK20058.1 - 3.8e-05 23.9 0.0 0.00016 21.9 0.0 2.1 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain DUF4527 PF15030.6 CRK20058.1 - 0.011 15.2 2.6 0.036 13.5 2.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4527) FTA4 PF13093.6 CRK20058.1 - 0.026 14.4 2.0 0.057 13.3 2.0 1.6 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Cofilin_ADF PF00241.20 CRK20058.1 - 0.18 11.6 0.0 0.42 10.4 0.0 1.6 1 0 0 1 1 1 0 Cofilin/tropomyosin-type actin-binding protein Proteasome PF00227.26 CRK20059.1 - 2.6e-47 160.8 0.1 3.4e-47 160.4 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 CRK20059.1 - 1.2e-12 47.0 0.1 1.2e-12 47.0 0.1 1.9 3 0 0 3 3 3 1 Proteasome beta subunits C terminal Sel1 PF08238.12 CRK20060.1 - 4.4e-12 46.3 8.3 0.0092 16.6 0.0 3.9 4 0 0 4 4 4 3 Sel1 repeat CSTF2_hinge PF14327.6 CRK20062.1 - 3.3e-33 114.0 2.8 6.9e-33 113.0 2.8 1.6 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 CRK20062.1 - 1.2e-21 76.3 0.0 1.8e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 CRK20062.1 - 2.1e-11 43.2 3.4 2.1e-11 43.2 3.4 3.4 4 0 0 4 4 4 1 Transcription termination and cleavage factor C-terminal Spo7_2_N PF15407.6 CRK20062.1 - 0.029 14.0 0.0 0.06 13.0 0.0 1.5 1 0 0 1 1 1 0 Sporulation protein family 7 RRM_7 PF16367.5 CRK20062.1 - 0.033 14.3 0.0 0.057 13.6 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif COPIIcoated_ERV PF07970.12 CRK20063.1 - 2.4e-76 256.4 0.0 8.4e-76 254.7 0.0 1.7 1 1 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 CRK20063.1 - 3.3e-30 104.3 0.2 1e-29 102.7 0.0 1.9 3 0 0 3 3 3 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) CorA PF01544.18 CRK20064.1 - 2.5e-34 118.9 0.2 1.3e-33 116.6 0.2 2.0 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein CBF PF03914.17 CRK20065.1 - 4.4e-33 114.7 0.2 4.4e-33 114.7 0.2 2.2 3 0 0 3 3 3 1 CBF/Mak21 family Mt_ATP-synt_B PF05405.14 CRK20066.1 - 1.4e-40 138.6 7.4 2e-40 138.1 7.4 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Dak2 PF02734.17 CRK20066.1 - 0.18 11.7 2.8 0.36 10.7 2.0 1.8 1 1 1 2 2 2 0 DAK2 domain MSC PF09402.10 CRK20067.1 - 6e-115 384.3 0.0 7.6e-115 384.0 0.0 1.1 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.7 CRK20067.1 - 1.1e-17 63.4 0.1 2.5e-17 62.3 0.1 1.7 1 0 0 1 1 1 1 HeH/LEM domain Thymopoietin PF08198.11 CRK20067.1 - 0.0012 18.4 0.0 0.0032 17.1 0.0 1.7 1 0 0 1 1 1 1 Thymopoietin protein FAD_binding_3 PF01494.19 CRK20068.1 - 2e-24 86.5 0.1 1.1e-22 80.8 0.1 2.2 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 CRK20068.1 - 8.1e-07 28.4 0.4 0.00017 20.7 0.1 3.0 2 1 0 2 2 2 1 Lycopene cyclase protein SE PF08491.10 CRK20068.1 - 0.00049 19.2 0.0 0.00079 18.5 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.24 CRK20068.1 - 0.00098 18.8 0.1 0.29 10.7 0.0 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 CRK20068.1 - 0.0031 17.5 0.0 0.0078 16.2 0.0 1.7 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 CRK20068.1 - 0.0037 16.5 0.0 0.031 13.5 0.0 1.9 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CRK20068.1 - 0.014 14.5 0.0 0.029 13.5 0.0 1.5 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 CRK20068.1 - 0.019 13.8 0.0 0.82 8.4 0.0 2.8 2 1 1 3 3 3 0 Tryptophan halogenase NAD_binding_8 PF13450.6 CRK20068.1 - 0.03 14.5 0.0 0.087 13.1 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CRK20068.1 - 0.036 13.3 0.0 0.39 9.9 0.0 2.0 2 0 0 2 2 2 0 Thi4 family Complex1_49kDa PF00346.19 CRK20069.1 - 7.1e-125 415.5 0.0 9.6e-125 415.1 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 CRK20069.1 - 0.013 14.4 0.0 0.019 13.9 0.0 1.3 1 0 0 1 1 1 0 Nickel-dependent hydrogenase SNase PF00565.17 CRK20070.1 - 1.7e-14 54.2 0.4 5e-13 49.5 0.4 2.2 1 1 0 1 1 1 1 Staphylococcal nuclease homologue Pkinase PF00069.25 CRK20071.1 - 1.2e-53 182.2 0.0 1.6e-53 181.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK20071.1 - 1.9e-40 138.8 0.0 2.8e-40 138.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CRK20071.1 - 0.00068 19.0 0.0 0.02 14.2 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CRK20071.1 - 0.0054 15.6 0.0 0.016 14.0 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 CRK20071.1 - 0.0098 15.8 0.0 0.17 11.8 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CRK20071.1 - 0.046 12.6 0.1 0.89 8.4 0.0 2.1 2 0 0 2 2 2 0 Haspin like kinase domain Kdo PF06293.14 CRK20071.1 - 0.25 10.7 0.0 1.1 8.6 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Telomere_reg-2 PF10193.9 CRK20072.1 - 3.9e-10 40.2 0.3 1.5e-08 35.1 0.0 2.6 3 0 0 3 3 3 1 Telomere length regulation protein HTH_13 PF11972.8 CRK20072.1 - 0.11 12.5 0.0 0.31 11.1 0.0 1.7 1 0 0 1 1 1 0 HTH DNA binding domain Ferritin_2 PF13668.6 CRK20076.1 - 8.8e-14 51.9 0.0 1.5e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 Ferritin-like domain AflR PF08493.10 CRK20076.1 - 0.043 13.3 3.7 0.064 12.7 3.7 1.3 1 0 0 1 1 1 0 Aflatoxin regulatory protein Mito_carr PF00153.27 CRK20077.1 - 1.4e-48 162.7 5.7 1.5e-17 63.3 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein UCH PF00443.29 CRK20078.1 - 8e-36 123.8 0.0 1.8e-35 122.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CRK20078.1 - 1.3e-19 70.9 0.0 2.4e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase SRP-alpha_N PF04086.13 CRK20078.1 - 0.00085 19.3 7.9 0.0017 18.3 7.9 1.5 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal AAA_11 PF13086.6 CRK20078.1 - 0.11 12.3 5.3 0.18 11.6 5.3 1.4 1 0 0 1 1 1 0 AAA domain Peptidase_C98 PF15499.6 CRK20078.1 - 1.5 8.2 12.6 0.16 11.4 0.9 2.7 3 0 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase DUF5427 PF10310.9 CRK20078.1 - 1.9 7.3 12.3 3.1 6.6 12.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5427) PP2C PF00481.21 CRK20079.1 - 3.5e-112 374.2 0.0 1.8e-55 188.4 0.0 2.5 2 0 0 2 2 2 2 Protein phosphatase 2C LRR_8 PF13855.6 CRK20079.1 - 1.1e-71 236.4 93.1 1.1e-09 37.9 0.3 16.4 6 6 10 16 16 16 16 Leucine rich repeat Guanylate_cyc PF00211.20 CRK20079.1 - 7.2e-60 201.7 0.0 3e-28 98.7 0.0 3.4 4 0 0 4 4 4 2 Adenylate and Guanylate cyclase catalytic domain LRR_4 PF12799.7 CRK20079.1 - 7.1e-56 185.2 118.6 0.0016 18.8 2.6 21.1 15 4 5 22 22 22 19 Leucine Rich repeats (2 copies) Ad_cyc_g-alpha PF08509.11 CRK20079.1 - 4.4e-22 77.5 2.4 4.4e-22 77.5 2.4 2.1 2 0 0 2 2 2 1 Adenylate cyclase G-alpha binding domain LRR_9 PF14580.6 CRK20079.1 - 2.4e-09 37.0 41.6 0.15 11.6 0.5 7.6 4 2 3 7 7 7 6 Leucine-rich repeat LRR_1 PF00560.33 CRK20079.1 - 4.2e-06 26.6 87.1 10 7.1 0.2 25.6 32 0 0 32 32 32 1 Leucine Rich Repeat LRR_6 PF13516.6 CRK20079.1 - 0.0005 19.9 71.3 1.8 8.8 0.2 19.0 22 0 0 22 22 22 4 Leucine Rich repeat AAA_18 PF13238.6 CRK20079.1 - 0.023 15.2 2.9 64 4.1 0.0 4.1 4 0 0 4 4 4 0 AAA domain RuvC PF02075.17 CRK20079.1 - 0.11 12.3 0.0 25 4.7 0.0 2.4 2 0 0 2 2 2 0 Crossover junction endodeoxyribonuclease RuvC Aminotran_3 PF00202.21 CRK20082.1 - 0.002 16.9 3.3 4.6 5.8 0.1 3.1 3 0 0 3 3 3 3 Aminotransferase class-III VirionAssem_T7 PF11653.8 CRK20082.1 - 0.037 14.5 0.6 16 6.1 0.0 3.0 3 0 0 3 3 3 0 Bacteriophage T7 virion assembly protein Alpha-amylase PF00128.24 CRK20083.1 - 9.6e-114 380.4 0.1 1.5e-113 379.8 0.1 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 CRK20083.1 - 2.8e-06 27.3 0.0 5.7e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 CRK20083.1 - 0.0044 16.2 0.0 0.0071 15.5 0.0 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain DUF3459 PF11941.8 CRK20083.1 - 0.015 15.6 0.1 0.058 13.7 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3459) Dynamitin PF04912.14 CRK20084.1 - 2e-108 363.2 1.0 2.3e-108 363.0 1.0 1.1 1 0 0 1 1 1 1 Dynamitin GrpE PF01025.19 CRK20084.1 - 0.0022 17.7 4.1 0.017 14.8 0.9 3.0 3 0 0 3 3 3 1 GrpE ATF7IP_BD PF16788.5 CRK20084.1 - 0.0044 17.2 0.0 0.011 15.9 0.0 1.6 1 0 0 1 1 1 1 ATF-interacting protein binding domain AIP3 PF03915.13 CRK20084.1 - 0.0071 15.5 0.3 0.092 11.8 0.1 2.1 2 0 0 2 2 2 1 Actin interacting protein 3 Laminin_II PF06009.12 CRK20084.1 - 0.0086 16.1 10.6 0.018 15.0 0.1 4.1 3 2 2 5 5 5 1 Laminin Domain II Corazonin PF17308.2 CRK20084.1 - 0.021 15.2 0.1 0.064 13.6 0.1 1.8 1 0 0 1 1 1 0 Pro-corazonin Spore_III_AB PF09548.10 CRK20084.1 - 0.023 14.8 2.0 0.067 13.3 0.2 2.6 3 1 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) FH2 PF02181.23 CRK20084.1 - 0.024 13.8 1.1 1.9 7.5 0.0 2.8 3 0 0 3 3 3 0 Formin Homology 2 Domain BLOC1_2 PF10046.9 CRK20084.1 - 0.025 14.9 3.8 34 4.8 0.0 3.7 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Baculo_PEP_C PF04513.12 CRK20084.1 - 0.067 13.2 2.2 2.2 8.3 0.2 3.2 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus IFT57 PF10498.9 CRK20084.1 - 0.094 11.7 1.3 1.3 7.9 0.0 2.7 3 0 0 3 3 3 0 Intra-flagellar transport protein 57 KxDL PF10241.9 CRK20084.1 - 0.12 12.7 3.3 9 6.7 0.1 3.4 4 0 0 4 4 3 0 Uncharacterized conserved protein SKA2 PF16740.5 CRK20084.1 - 0.12 12.1 3.6 4.3 7.2 0.0 3.2 3 1 0 3 3 3 0 Spindle and kinetochore-associated protein 2 DUF2894 PF11445.8 CRK20084.1 - 0.28 11.6 12.5 1.2 9.6 2.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) ZapB PF06005.12 CRK20084.1 - 0.42 11.1 9.8 5.1 7.6 0.7 3.5 3 0 0 3 3 3 0 Cell division protein ZapB DUF2203 PF09969.9 CRK20084.1 - 0.42 11.3 11.6 10 6.8 0.1 3.4 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) DUF724 PF05266.14 CRK20084.1 - 0.44 10.3 11.1 1.5 8.6 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF724) MnmE_helical PF12631.7 CRK20084.1 - 0.53 10.4 6.5 3.4 7.8 0.6 2.2 2 0 0 2 2 2 0 MnmE helical domain Prefoldin_2 PF01920.20 CRK20084.1 - 0.82 9.7 0.0 0.82 9.7 0.0 3.9 4 0 0 4 4 4 0 Prefoldin subunit FlgN PF05130.12 CRK20084.1 - 0.89 10.1 15.7 0.34 11.4 2.3 2.9 2 1 1 3 3 3 0 FlgN protein SOGA PF11365.8 CRK20084.1 - 0.92 10.7 5.9 6.4 8.0 0.0 3.2 3 0 0 3 3 3 0 Protein SOGA DUF1664 PF07889.12 CRK20084.1 - 1.1 9.3 5.1 4.4 7.4 0.1 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) DHR10 PF18595.1 CRK20084.1 - 1.2 9.2 17.9 4.5 7.4 0.1 4.2 3 1 2 5 5 5 0 Designed helical repeat protein 10 domain Phage_GP20 PF06810.11 CRK20084.1 - 1.4 8.7 11.0 0.15 11.9 2.9 2.8 3 0 0 3 3 3 0 Phage minor structural protein GP20 DUF1192 PF06698.11 CRK20084.1 - 1.9 8.6 18.2 0.6 10.2 4.1 3.6 4 1 0 4 4 3 0 Protein of unknown function (DUF1192) DivIC PF04977.15 CRK20084.1 - 3.6 7.4 15.3 1 9.2 0.3 4.3 4 0 0 4 4 4 0 Septum formation initiator OmpH PF03938.14 CRK20084.1 - 5.4 7.4 11.3 3.5 8.0 1.8 3.2 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) DASH_Spc19 PF08287.11 CRK20084.1 - 8.2 6.3 10.2 0.33 10.8 1.2 2.4 2 1 0 2 2 2 0 Spc19 HAUS6_N PF14661.6 CRK20084.1 - 8.3 5.9 6.6 37 3.8 0.0 3.0 3 1 0 3 3 3 0 HAUS augmin-like complex subunit 6 N-terminus PSI PF01437.25 CRK20085.1 - 0.00035 21.0 9.6 0.00052 20.5 9.6 1.4 1 0 0 1 1 1 1 Plexin repeat HemY_N PF07219.13 CRK20085.1 - 0.017 15.3 0.1 0.025 14.8 0.1 1.3 1 0 0 1 1 1 0 HemY protein N-terminus PSI_integrin PF17205.3 CRK20085.1 - 0.035 13.8 8.3 0.063 13.0 8.3 1.4 1 0 0 1 1 1 0 Integrin plexin domain FeoB_associated PF12669.7 CRK20085.1 - 0.31 11.5 0.1 0.31 11.5 0.1 2.2 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein Sugar_tr PF00083.24 CRK20086.1 - 1.8e-82 277.6 18.1 2.2e-82 277.3 18.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK20086.1 - 1.3e-26 93.4 20.7 1.3e-26 93.4 20.7 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 CRK20086.1 - 7.4e-06 24.7 0.7 7.4e-06 24.7 0.7 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Complex1_LYR PF05347.15 CRK20088.1 - 1.9e-15 56.6 1.9 2.2e-15 56.4 1.9 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 CRK20088.1 - 2.3e-07 31.5 0.3 2.7e-07 31.2 0.3 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 CRK20088.1 - 0.0093 16.5 0.4 0.029 15.0 0.3 1.7 1 1 1 2 2 2 1 Complex1_LYR-like IBR PF01485.21 CRK20089.1 - 1.2e-06 28.6 33.3 0.00014 22.0 11.1 3.1 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain COesterase PF00135.28 CRK20090.1 - 7.5e-80 269.2 0.0 8.5e-80 269.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CRK20090.1 - 0.00054 19.9 0.0 0.0014 18.5 0.0 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CRK20090.1 - 0.038 13.5 0.0 0.06 12.8 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family F-box-like PF12937.7 CRK20091.1 - 0.0002 21.2 0.1 0.00041 20.2 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CRK20091.1 - 0.16 11.9 0.0 0.37 10.7 0.0 1.5 1 0 0 1 1 1 0 F-box domain TcdA_TcdB_pore PF12920.7 CRK20092.1 - 0.039 12.2 0.1 0.046 12.0 0.1 1.0 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain DivIVA PF05103.13 CRK20092.1 - 0.04 14.0 4.6 0.056 13.5 4.6 1.2 1 0 0 1 1 1 0 DivIVA protein Apolipoprotein PF01442.18 CRK20092.1 - 0.048 13.5 11.5 0.59 10.0 1.2 2.0 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain Nup54 PF13874.6 CRK20092.1 - 0.066 13.3 5.9 0.088 12.9 5.9 1.2 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 MAP7 PF05672.11 CRK20092.1 - 0.63 9.7 9.6 2 8.1 9.6 1.7 1 1 0 1 1 1 0 MAP7 (E-MAP-115) family Sugar_tr PF00083.24 CRK20093.1 - 5.8e-80 269.4 18.2 5.8e-80 269.4 18.2 2.1 2 1 1 3 3 3 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK20093.1 - 3.1e-33 115.1 42.8 1.5e-22 80.0 21.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Mem_trans PF03547.18 CRK20093.1 - 0.00026 19.5 1.3 0.46 8.8 0.0 3.9 2 2 1 3 3 3 1 Membrane transport protein G-patch PF01585.23 CRK20093.1 - 0.00064 19.6 0.0 0.0021 17.9 0.0 2.0 1 1 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 CRK20093.1 - 0.61 10.2 0.0 0.61 10.2 0.0 3.2 3 1 0 3 3 3 0 G-patch domain Mitofilin PF09731.9 CRK20093.1 - 0.81 8.5 40.3 0.24 10.2 37.3 1.7 2 0 0 2 2 2 0 Mitochondrial inner membrane protein Hid1 PF12722.7 CRK20093.1 - 1.3 7.0 22.7 2.1 6.4 22.7 1.4 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein ATPgrasp_ST PF14397.6 CRK20095.1 - 0.00011 21.6 0.1 0.3 10.3 0.0 2.1 1 1 1 2 2 2 2 Sugar-transfer associated ATP-grasp HLH PF00010.26 CRK20095.1 - 0.0014 18.5 0.5 0.31 11.0 0.0 3.1 4 0 0 4 4 4 2 Helix-loop-helix DNA-binding domain COE1_HLH PF16423.5 CRK20095.1 - 0.12 12.1 0.0 24 4.7 0.0 2.5 2 0 0 2 2 2 0 Transcription factor COE1 helix-loop-helix domain TAL_FSA PF00923.19 CRK20096.1 - 4.6e-29 101.7 0.0 7e-29 101.1 0.0 1.2 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Sugar_tr PF00083.24 CRK20097.1 - 5.7e-72 243.0 23.0 7.4e-72 242.6 23.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK20097.1 - 2.1e-13 49.9 32.2 3.4e-13 49.2 32.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily PITH PF06201.13 CRK20099.1 - 2.7e-36 125.1 0.0 5e-36 124.2 0.0 1.5 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.20 CRK20099.1 - 1.7e-28 98.6 0.2 3.1e-28 97.8 0.2 1.4 1 0 0 1 1 1 1 Thioredoxin C166 PF17615.2 CRK20099.1 - 3.9e-27 95.3 7.9 6.5e-27 94.6 7.9 1.3 1 0 0 1 1 1 1 Family of unknown function Thioredoxin_2 PF13098.6 CRK20099.1 - 3.3e-07 30.7 0.1 7.1e-07 29.7 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 CRK20099.1 - 6.4e-05 22.7 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 CRK20099.1 - 0.00013 21.4 0.1 0.00024 20.5 0.1 1.4 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 CRK20099.1 - 0.00049 20.4 0.0 0.0027 18.0 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 CRK20099.1 - 0.00089 19.2 0.0 0.0029 17.5 0.0 1.9 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CRK20099.1 - 0.0043 16.8 0.2 0.38 10.4 0.1 2.4 1 1 1 2 2 2 1 Redoxin Thioredoxin_7 PF13899.6 CRK20099.1 - 0.012 15.8 0.2 0.023 14.9 0.2 1.5 1 0 0 1 1 1 0 Thioredoxin-like Phosducin PF02114.16 CRK20099.1 - 0.014 14.4 0.0 0.022 13.7 0.0 1.2 1 0 0 1 1 1 0 Phosducin Serglycin PF04360.12 CRK20099.1 - 0.051 13.5 1.3 0.093 12.7 1.3 1.3 1 0 0 1 1 1 0 Serglycin RhlB PF12300.8 CRK20099.1 - 0.23 11.6 3.1 0.47 10.6 3.1 1.5 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB adh_short PF00106.25 CRK20101.1 - 9.2e-25 87.2 0.7 2.5e-21 76.0 0.5 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CRK20101.1 - 1.5e-13 50.9 1.3 4.4e-12 46.1 0.8 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK20101.1 - 7.6e-09 35.7 0.4 2e-08 34.4 0.1 1.7 2 0 0 2 2 2 1 KR domain Pyridox_ox_2 PF12900.7 CRK20104.1 - 1e-25 90.3 0.0 1.2e-25 90.1 0.0 1.0 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Arm PF00514.23 CRK20107.1 - 1.8e-07 30.9 1.0 0.16 12.1 0.0 4.3 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat HEAT PF02985.22 CRK20107.1 - 0.00076 19.5 3.6 4.9 7.7 0.1 4.6 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.6 CRK20107.1 - 0.1 13.1 0.1 6.9 7.3 0.0 3.0 2 0 0 2 2 2 0 HEAT-like repeat PI-PLC-X PF00388.19 CRK20120.1 - 3.2e-08 33.3 0.1 4.1e-08 32.9 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain SH3_9 PF14604.6 CRK20143.1 - 1.6e-07 31.1 0.0 2.4e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CRK20143.1 - 4.4e-06 26.2 0.0 7.5e-06 25.5 0.0 1.5 1 1 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CRK20143.1 - 0.0041 16.8 0.0 0.0052 16.4 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Suppressor_APC PF11414.8 CRK20145.1 - 0.14 12.3 0.3 0.14 12.3 0.3 1.8 2 0 0 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein TPR_1 PF00515.28 CRK20148.1 - 2.2e-44 147.5 20.5 2.3e-05 24.0 0.2 9.4 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.17 CRK20148.1 - 1.6e-38 127.7 17.3 1.4e-05 24.8 0.1 9.4 9 0 0 9 9 9 8 Tetratricopeptide repeat STI1 PF17830.1 CRK20148.1 - 5.1e-34 116.0 14.6 5.2e-17 61.5 3.0 3.0 3 0 0 3 3 2 2 STI1 domain TPR_11 PF13414.6 CRK20148.1 - 7.7e-25 86.3 14.8 9.8e-05 22.0 0.1 7.5 7 0 0 7 7 7 6 TPR repeat TPR_8 PF13181.6 CRK20148.1 - 1.3e-16 59.3 16.4 0.0011 19.0 0.1 8.0 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 CRK20148.1 - 3.7e-16 59.5 6.5 0.00051 20.6 0.1 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 CRK20148.1 - 6.3e-16 57.7 5.4 0.35 11.8 0.0 8.5 4 3 4 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 CRK20148.1 - 4.7e-14 51.7 7.0 0.11 12.9 0.0 8.2 8 1 0 8 8 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 CRK20148.1 - 5.4e-14 52.2 12.7 3.3e-08 33.7 0.4 5.7 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 CRK20148.1 - 8.5e-13 48.3 0.9 0.00016 21.8 0.0 5.2 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 CRK20148.1 - 3.2e-12 46.8 11.2 0.039 14.4 0.2 6.7 5 2 2 7 7 6 5 Tetratricopeptide repeat TPR_7 PF13176.6 CRK20148.1 - 4.9e-10 38.7 7.5 0.005 16.8 0.0 6.3 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_10 PF13374.6 CRK20148.1 - 1.4e-05 24.8 18.6 0.24 11.3 0.1 7.4 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_6 PF13174.6 CRK20148.1 - 0.00038 20.9 14.6 0.67 10.7 0.0 7.5 8 0 0 8 8 6 1 Tetratricopeptide repeat DUF5486 PF17588.2 CRK20148.1 - 0.028 14.3 2.6 0.13 12.2 1.0 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5486) CODH_A_N PF18537.1 CRK20148.1 - 0.051 13.6 0.0 0.37 10.8 0.0 2.4 2 0 0 2 2 2 0 Carbon monoxide dehydrogenase subunit alpha N-terminal domain ANAPC3 PF12895.7 CRK20148.1 - 0.11 12.8 6.9 0.87 9.9 1.4 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.9 CRK20148.1 - 0.13 11.8 2.8 21 4.7 0.0 4.4 5 0 0 5 5 5 0 SHNi-TPR TPR_20 PF14561.6 CRK20148.1 - 0.31 11.4 10.7 0.34 11.3 0.1 4.9 4 1 1 5 5 5 0 Tetratricopeptide repeat XPC-binding PF09280.11 CRK20148.1 - 0.91 9.3 7.6 3.9 7.3 0.9 3.6 3 0 0 3 3 3 0 XPC-binding domain MIT PF04212.18 CRK20148.1 - 2.3 8.3 14.7 10 6.3 0.1 5.4 6 0 0 6 6 5 0 MIT (microtubule interacting and transport) domain Sugar_tr PF00083.24 CRK20149.1 - 2.4e-80 270.6 20.7 2.9e-80 270.3 20.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK20149.1 - 6.6e-29 100.9 25.4 9.4e-29 100.4 25.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1659 PF07872.11 CRK20149.1 - 0.0039 16.8 0.0 0.0079 15.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1659) Phage_holin_3_2 PF04550.12 CRK20149.1 - 2 9.0 9.9 0.52 10.9 2.8 3.1 3 1 1 4 4 4 0 Phage holin family 2 C166 PF17615.2 CRK20151.1 - 2.9e-09 37.3 0.4 8.9e-09 35.7 0.4 1.9 1 1 0 1 1 1 1 Family of unknown function HsbA PF12296.8 CRK20151.1 - 3.1e-05 24.4 0.7 0.00018 21.9 0.2 2.1 1 1 1 2 2 2 1 Hydrophobic surface binding protein A Fungal_trans PF04082.18 CRK20153.1 - 1.9e-21 76.3 0.0 3e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Imm49 PF15575.6 CRK20155.1 - 0.024 14.4 0.1 0.039 13.7 0.1 1.3 1 0 0 1 1 1 0 Immunity protein 49 2-Hacid_dh_C PF02826.19 CRK20156.1 - 7.5e-43 145.9 0.0 9e-30 103.3 0.0 2.1 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Vta1 PF04652.16 CRK20158.1 - 1.4e-52 177.5 2.3 1.8e-52 177.1 2.3 1.1 1 0 0 1 1 1 1 Vta1 like Vta1_C PF18097.1 CRK20158.1 - 4.4e-14 51.9 1.1 6.4e-14 51.4 0.0 1.8 2 0 0 2 2 2 1 Vta1 C-terminal domain Thioredoxin PF00085.20 CRK20159.1 - 9e-33 112.4 0.0 2.5e-26 91.7 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin OST3_OST6 PF04756.13 CRK20159.1 - 1.2e-06 28.1 0.0 5.1e-06 26.0 0.0 1.8 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 CRK20159.1 - 3.8e-06 27.3 0.1 0.047 14.1 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CRK20159.1 - 4.8e-05 23.6 0.0 6.6 7.1 0.0 4.0 3 1 1 4 4 4 1 Thioredoxin-like HyaE PF07449.11 CRK20159.1 - 0.017 15.1 0.0 2.2 8.3 0.0 2.7 2 1 0 2 2 2 0 Hydrogenase-1 expression protein HyaE AhpC-TSA PF00578.21 CRK20159.1 - 0.04 13.8 0.0 0.18 11.7 0.0 2.1 1 0 0 1 1 1 0 AhpC/TSA family QSOX_Trx1 PF18108.1 CRK20159.1 - 0.048 13.8 0.0 0.14 12.3 0.0 1.7 2 0 0 2 2 2 0 QSOX Trx-like domain TraF PF13728.6 CRK20159.1 - 0.09 12.6 0.0 0.09 12.6 0.0 3.4 4 0 0 4 4 4 0 F plasmid transfer operon protein Thioredoxin_3 PF13192.6 CRK20159.1 - 0.14 12.2 0.1 5.3 7.2 0.0 2.6 2 0 0 2 2 2 0 Thioredoxin domain Glutaredoxin PF00462.24 CRK20159.1 - 0.14 12.4 0.2 15 5.9 0.0 2.5 2 0 0 2 2 2 0 Glutaredoxin Thioredoxin_7 PF13899.6 CRK20159.1 - 0.16 12.2 0.0 0.43 10.8 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin-like RNase_PH PF01138.21 CRK20160.1 - 1.1e-35 123.0 0.1 1.8e-35 122.3 0.1 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 NIF PF03031.18 CRK20161.1 - 1.5e-27 96.3 0.0 2.3e-27 95.7 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ABM PF03992.16 CRK20163.1 - 0.13 12.4 0.6 0.28 11.3 0.1 1.8 2 0 0 2 2 2 0 Antibiotic biosynthesis monooxygenase Pro_dh PF01619.18 CRK20164.1 - 3.2e-71 240.3 0.0 4.6e-71 239.8 0.0 1.2 1 0 0 1 1 1 1 Proline dehydrogenase Tim17 PF02466.19 CRK20164.1 - 3.1e-06 27.5 1.5 9.9e-06 25.9 1.1 2.1 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family CGI-121 PF08617.10 CRK20166.1 - 4.8e-53 179.6 0.0 5.5e-53 179.4 0.0 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 MlrC_C PF07171.12 CRK20166.1 - 0.046 13.9 0.0 0.084 13.0 0.0 1.4 1 0 0 1 1 1 0 MlrC C-terminus Fungal_trans PF04082.18 CRK20167.1 - 7.5e-08 31.7 0.6 1.5e-07 30.8 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK20167.1 - 2.9e-07 30.5 6.9 4.9e-07 29.8 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2722 PF10846.8 CRK20167.1 - 0.0095 14.9 11.5 0.014 14.4 11.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Dala_Dala_lig_N PF01820.21 CRK20167.1 - 0.012 16.0 0.5 0.03 14.8 0.5 1.6 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus EPL1 PF10513.9 CRK20167.1 - 0.069 13.5 3.1 0.45 10.9 3.7 2.1 2 0 0 2 2 2 0 Enhancer of polycomb-like MPM1 PF17234.2 CRK20167.1 - 0.098 12.9 4.8 0.21 11.8 4.8 1.5 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 DUF4834 PF16118.5 CRK20167.1 - 0.12 13.3 5.1 0.34 11.9 5.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Borrelia_P83 PF05262.11 CRK20167.1 - 0.14 10.6 4.1 0.23 9.9 4.1 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Spt20 PF12090.8 CRK20167.1 - 0.32 10.6 22.2 0.77 9.3 22.2 1.5 1 0 0 1 1 1 0 Spt20 family Presenilin PF01080.17 CRK20167.1 - 0.32 9.7 3.1 0.55 8.9 3.1 1.3 1 0 0 1 1 1 0 Presenilin DUF5421 PF17458.2 CRK20167.1 - 1.5 8.1 8.7 2.7 7.3 8.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5421) EMC3_TMCO1 PF01956.16 CRK20167.1 - 1.8 8.2 4.7 4.9 6.9 2.6 2.3 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like TMEM51 PF15345.6 CRK20167.1 - 5.3 6.8 14.1 4.1 7.2 11.1 2.0 2 0 0 2 2 2 0 Transmembrane protein 51 Abhydrolase_1 PF00561.20 CRK20168.1 - 7.3e-13 48.8 3.1 4.1e-11 43.0 1.5 2.4 2 1 0 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CRK20168.1 - 1e-11 45.9 0.3 1.7e-11 45.2 0.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CRK20168.1 - 5.3e-11 42.2 0.3 7.8e-11 41.7 0.3 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 CRK20168.1 - 0.0087 16.2 0.1 0.014 15.6 0.1 1.3 1 0 0 1 1 1 1 Thioesterase domain Peptidase_S15 PF02129.18 CRK20168.1 - 0.15 11.6 0.2 0.33 10.5 0.2 1.6 1 1 1 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Glyco_hydro_115 PF15979.5 CRK20172.1 - 2.3e-131 438.3 2.1 3.6e-131 437.6 2.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 CRK20172.1 - 8.9e-40 136.3 0.0 2.7e-39 134.8 0.0 1.8 2 0 0 2 2 2 1 Gylcosyl hydrolase family 115 C-terminal domain Kinesin PF00225.23 CRK20174.1 - 2.4e-116 388.3 0.0 3.4e-116 387.8 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CRK20174.1 - 1.6e-27 96.3 0.0 3.6e-27 95.1 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding AAA_33 PF13671.6 CRK20174.1 - 0.045 13.9 0.2 0.22 11.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain Herpes_UL14 PF03580.14 CRK20174.1 - 0.061 13.6 2.4 0.13 12.5 2.4 1.5 1 0 0 1 1 1 0 Herpesvirus UL14-like protein DUF2526 PF10735.9 CRK20174.1 - 0.45 10.7 2.7 1.5 9.0 2.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2526) YjbE PF11106.8 CRK20176.1 - 0.29 11.4 1.7 0.62 10.3 1.7 1.5 1 0 0 1 1 1 0 Exopolysaccharide production protein YjbE Fungal_trans PF04082.18 CRK20177.1 - 6.6e-12 45.0 0.1 5.4e-11 42.0 0.0 2.4 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK20177.1 - 4.3e-08 33.2 12.2 4.3e-08 33.2 12.2 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IFN-gamma PF00714.17 CRK20177.1 - 0.14 12.0 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 Interferon gamma COesterase PF00135.28 CRK20178.1 - 7.3e-59 200.0 0.0 3.7e-58 197.6 0.0 1.9 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CRK20178.1 - 7.1e-06 26.0 0.1 4.7e-05 23.3 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Glyco_hydro_18 PF00704.28 CRK20179.1 - 3.4e-82 276.7 4.5 4e-82 276.4 4.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 WD40 PF00400.32 CRK20179.1 - 6.8e-11 42.5 3.6 3e-05 24.7 0.7 2.8 2 0 0 2 2 2 2 WD domain, G-beta repeat GPP34 PF05719.11 CRK20181.1 - 1.2e-30 107.0 0.2 1.5e-30 106.8 0.2 1.0 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) RNase_PH PF01138.21 CRK20182.1 - 7e-18 65.4 0.0 9.6e-18 65.0 0.0 1.1 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Peptidase_M14 PF00246.24 CRK20185.1 - 4.7e-29 102.1 0.1 5e-29 102.0 0.1 1.0 1 0 0 1 1 1 1 Zinc carboxypeptidase Cation_ATPase PF13246.6 CRK20186.1 - 3.5e-21 75.1 0.0 5.4e-21 74.5 0.0 1.3 1 0 0 1 1 1 1 Cation transport ATPase (P-type) SAP130_C PF16014.5 CRK20186.1 - 0.23 10.5 2.3 0.29 10.2 2.3 1.1 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus IBN_N PF03810.19 CRK20213.1 - 1.7e-05 24.6 1.2 0.00078 19.3 0.2 3.3 2 1 1 3 3 3 1 Importin-beta N-terminal domain HEAT PF02985.22 CRK20213.1 - 0.00027 20.9 0.1 4.8 7.7 0.0 4.2 4 0 0 4 4 4 1 HEAT repeat Cnd1 PF12717.7 CRK20213.1 - 0.019 15.0 0.0 0.037 14.1 0.0 1.5 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 CRK20213.1 - 0.083 12.4 0.0 0.28 10.7 0.0 1.8 1 1 0 2 2 2 0 CLASP N terminal HEAT_EZ PF13513.6 CRK20213.1 - 0.085 13.4 2.2 19 5.9 0.0 3.3 2 2 1 3 3 3 0 HEAT-like repeat Vps39_2 PF10367.9 CRK20220.1 - 1.8e-30 105.6 0.0 2.8e-30 105.0 0.0 1.3 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CitMHS PF03600.16 CRK20220.1 - 1.8e-07 30.6 0.1 2.6e-07 30.2 0.1 1.2 1 0 0 1 1 1 1 Citrate transporter Na_sulph_symp PF00939.19 CRK20220.1 - 9.1e-05 21.7 0.2 0.00011 21.4 0.2 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region UvrD-helicase PF00580.21 CRK20222.1 - 3.2e-62 210.9 0.0 4.6e-60 203.8 0.0 2.3 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 CRK20222.1 - 6.9e-62 209.8 0.0 4.6e-61 207.1 0.0 2.0 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 CRK20222.1 - 8.2e-31 107.3 0.0 1.8e-30 106.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 CRK20222.1 - 2.6e-14 52.8 0.6 5.6e-14 51.7 0.0 2.0 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 CRK20222.1 - 6.7e-08 32.5 0.3 0.0011 18.7 0.1 2.5 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 CRK20222.1 - 3.4e-05 23.7 0.0 0.4 10.4 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.6 CRK20222.1 - 0.00025 20.7 0.0 0.0019 17.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain Ribosomal_L22 PF00237.19 CRK20222.1 - 0.037 14.2 0.2 22 5.4 0.0 3.7 4 0 0 4 4 4 0 Ribosomal protein L22p/L17e AAA_22 PF13401.6 CRK20222.1 - 0.064 13.5 0.2 3 8.1 0.2 2.6 1 1 0 1 1 1 0 AAA domain Pyr_redox_2 PF07992.14 CRK20223.1 - 3.4e-43 148.0 1.4 5.2e-43 147.4 1.4 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR PF01077.22 CRK20223.1 - 3.9e-19 68.7 0.0 7.4e-19 67.8 0.0 1.5 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox PF00070.27 CRK20223.1 - 7.1e-18 65.0 2.9 1e-16 61.3 0.4 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Fer2_BFD PF04324.15 CRK20223.1 - 1.8e-14 53.8 13.2 2.3e-12 47.0 5.5 3.0 3 0 0 3 3 3 2 BFD-like [2Fe-2S] binding domain Rieske PF00355.26 CRK20223.1 - 4.2e-13 49.0 0.7 7.3e-12 45.1 0.0 3.1 3 1 0 3 3 3 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 CRK20223.1 - 1.3e-12 47.6 0.0 9.9e-05 22.2 0.0 2.9 2 1 0 3 3 2 2 Rieske-like [2Fe-2S] domain NIR_SIR_ferr PF03460.17 CRK20223.1 - 3e-08 33.4 0.0 9.8e-08 31.7 0.0 1.9 2 0 0 2 2 2 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rubredoxin_C PF18267.1 CRK20223.1 - 5e-05 23.1 0.1 1.1 9.2 0.0 4.3 5 0 0 5 5 5 2 Rubredoxin NAD+ reductase C-terminal domain Pyr_redox_3 PF13738.6 CRK20223.1 - 0.0011 18.3 0.0 0.002 17.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CRK20223.1 - 0.0053 16.8 1.4 2.9 7.9 0.0 3.7 3 1 1 4 4 4 1 FAD-NAD(P)-binding Amino_oxidase PF01593.24 CRK20223.1 - 0.033 13.5 3.2 2.8 7.1 0.1 2.6 2 1 1 3 3 3 0 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 CRK20223.1 - 0.17 11.1 3.8 1.9 7.7 0.0 2.5 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_23 PF13489.6 CRK20224.1 - 1.5e-20 73.7 0.0 2.2e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CRK20224.1 - 3.8e-20 72.3 0.0 6.4e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK20224.1 - 6.8e-16 58.8 0.0 1.4e-15 57.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK20224.1 - 7.2e-14 52.3 0.0 1.2e-13 51.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK20224.1 - 6.7e-11 42.2 0.0 1e-10 41.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 CRK20224.1 - 0.00024 20.1 0.0 0.00036 19.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PrmA PF06325.13 CRK20224.1 - 0.0014 18.1 0.0 0.002 17.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 CRK20224.1 - 0.0042 16.6 0.0 0.0078 15.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 CRK20224.1 - 0.015 14.6 0.0 0.04 13.2 0.0 1.6 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase NodS PF05401.11 CRK20224.1 - 0.031 13.9 0.0 0.048 13.3 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) DHBP_synthase PF00926.19 CRK20225.1 - 3.1e-09 36.7 0.0 4e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase DAO PF01266.24 CRK20227.1 - 5.6e-31 108.4 0.0 8.3e-31 107.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 CRK20227.1 - 0.00014 20.9 0.1 0.15 10.9 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox_2 PF07992.14 CRK20227.1 - 0.00042 19.6 0.0 0.037 13.3 0.0 2.2 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Clavanin PF05452.11 CRK20227.1 - 0.0021 18.2 0.0 6.4 7.0 0.0 3.1 3 0 0 3 3 3 2 Clavanin NAD_binding_9 PF13454.6 CRK20227.1 - 0.01 15.8 0.4 6.7 6.7 0.1 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding K_oxygenase PF13434.6 CRK20227.1 - 0.014 14.6 0.0 0.031 13.4 0.0 1.5 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 CRK20227.1 - 0.03 14.6 0.1 0.15 12.3 0.0 2.3 3 0 0 3 3 1 0 NAD(P)-binding Rossmann-like domain GMC_oxred_N PF00732.19 CRK20227.1 - 0.044 13.2 0.0 0.92 8.8 0.0 2.3 2 0 0 2 2 2 0 GMC oxidoreductase DUF538 PF04398.12 CRK20227.1 - 0.052 14.0 0.0 1.3 9.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF538 GST_N_4 PF17172.4 CRK20227.1 - 0.062 14.1 0.0 19 6.1 0.0 2.6 2 0 0 2 2 2 0 Glutathione S-transferase N-terminal domain TrkA_N PF02254.18 CRK20227.1 - 0.11 12.7 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_3 PF13738.6 CRK20227.1 - 0.12 11.7 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans_2 PF11951.8 CRK20229.1 - 1.6e-24 86.5 0.4 2.9e-20 72.4 0.2 2.1 1 1 0 2 2 2 2 Fungal specific transcription factor domain HycA_repressor PF11046.8 CRK20229.1 - 0.0021 18.3 0.0 1.4 9.1 0.0 2.2 2 0 0 2 2 2 2 Transcriptional repressor of hyc and hyp operons TFIIB PF00382.19 CRK20229.1 - 0.088 12.9 0.1 0.24 11.5 0.1 1.8 1 0 0 1 1 1 0 Transcription factor TFIIB repeat Secapin PF17521.2 CRK20229.1 - 0.13 12.1 0.3 28 4.6 0.0 2.7 2 0 0 2 2 2 0 Honey bee peptides Methyltransf_33 PF10017.9 CRK20230.1 - 7.5e-77 258.5 0.0 9.4e-77 258.2 0.0 1.0 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent zf-C2H2 PF00096.26 CRK20232.1 - 9.8e-23 79.3 25.9 7.1e-06 26.2 0.2 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CRK20232.1 - 2.2e-17 62.6 25.6 1.7e-06 28.2 1.2 5.6 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 CRK20232.1 - 2.1e-06 28.1 42.2 0.0041 17.8 1.3 5.3 5 0 0 5 5 4 4 C2H2-type zinc finger zf-met PF12874.7 CRK20232.1 - 0.0002 21.6 7.1 1.1 9.8 0.0 4.3 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 CRK20232.1 - 0.00098 18.8 8.1 0.02 14.6 0.8 3.2 3 0 0 3 3 3 2 zinc-finger C2H2-type zf_UBZ PF18439.1 CRK20232.1 - 0.0022 17.5 1.7 1.2 8.8 0.2 3.3 3 0 0 3 3 3 2 Ubiquitin-Binding Zinc Finger zf-C2H2_jaz PF12171.8 CRK20232.1 - 0.13 12.6 13.5 12 6.3 0.0 4.8 5 0 0 5 5 4 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 CRK20232.1 - 0.42 10.6 7.6 9.8 6.2 0.3 3.5 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Zn-ribbon_8 PF09723.10 CRK20232.1 - 0.52 10.5 8.8 3.2 7.9 1.0 3.3 1 1 3 4 4 4 0 Zinc ribbon domain DZR PF12773.7 CRK20232.1 - 1 9.5 7.5 58 3.8 7.5 2.4 1 1 0 1 1 1 0 Double zinc ribbon zf-LYAR PF08790.11 CRK20232.1 - 1.1 9.2 4.0 6.2 6.8 0.1 3.5 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger Ogr_Delta PF04606.12 CRK20232.1 - 1.8 8.6 9.2 3.3 7.8 0.4 2.5 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger DUF2256 PF10013.9 CRK20232.1 - 2.9 8.1 8.5 22 5.2 0.0 3.7 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) Zn_ribbon_recom PF13408.6 CRK20232.1 - 3 8.4 9.8 4.5 7.9 2.4 2.6 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain DSBA PF01323.20 CRK20233.1 - 4.3e-26 91.9 0.0 2.3e-13 50.3 0.0 2.0 2 0 0 2 2 2 2 DSBA-like thioredoxin domain Thioredoxin_3 PF13192.6 CRK20233.1 - 0.027 14.5 0.1 3.1 7.9 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin domain Thioredoxin_4 PF13462.6 CRK20233.1 - 0.16 12.2 0.0 0.54 10.4 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin Thioredoxin_5 PF13743.6 CRK20233.1 - 0.2 11.3 0.0 0.39 10.4 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin F-actin_cap_A PF01267.17 CRK20235.1 - 3.9e-88 295.3 0.0 6.1e-88 294.7 0.0 1.2 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Transket_pyr PF02779.24 CRK20235.1 - 2.9e-43 147.6 0.1 6.4e-43 146.5 0.1 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 CRK20235.1 - 2.8e-32 111.2 0.0 7.8e-32 109.8 0.0 1.8 1 0 0 1 1 1 1 Transketolase, C-terminal domain adh_short PF00106.25 CRK20235.1 - 6.6e-24 84.5 0.0 2.7e-20 72.7 0.0 2.4 2 0 0 2 2 2 2 short chain dehydrogenase Cyt-b5 PF00173.28 CRK20235.1 - 7.1e-22 77.3 0.2 1.4e-21 76.4 0.2 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain adh_short_C2 PF13561.6 CRK20235.1 - 8.4e-19 68.1 0.0 2.8e-18 66.4 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK20235.1 - 2.3e-05 24.4 0.1 9.7e-05 22.4 0.0 2.1 2 0 0 2 2 2 1 KR domain PFOR_II PF17147.4 CRK20235.1 - 0.0051 17.1 0.0 0.013 15.7 0.0 1.7 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Epimerase PF01370.21 CRK20235.1 - 0.046 13.2 0.1 0.16 11.4 0.0 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 CRK20235.1 - 0.058 14.0 0.0 0.17 12.5 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Cellulase PF00150.18 CRK20236.1 - 1.2e-11 44.5 0.7 2.4e-11 43.6 0.7 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PLAT PF01477.23 CRK20236.1 - 0.0075 16.8 0.4 0.019 15.5 0.0 1.8 2 0 0 2 2 2 1 PLAT/LH2 domain EphA2_TM PF14575.6 CRK20236.1 - 0.019 15.8 0.0 0.019 15.8 0.0 2.9 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 CRK20236.1 - 0.078 12.9 0.1 0.2 11.5 0.1 1.6 1 0 0 1 1 1 0 TMEM154 protein family ODV-E18 PF10717.9 CRK20236.1 - 0.08 12.8 0.4 0.16 11.9 0.4 1.4 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Zn_clus PF00172.18 CRK20237.1 - 0.0019 18.3 8.9 0.0043 17.2 8.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 CRK20237.1 - 0.013 15.5 0.0 0.025 14.6 0.0 1.4 1 0 0 1 1 1 0 PAS fold Flavokinase PF01687.17 CRK20238.1 - 1e-72 241.5 0.0 5.6e-35 120.0 0.0 2.0 2 0 0 2 2 2 2 Riboflavin kinase eIF3_N PF09440.10 CRK20238.1 - 0.45 11.0 1.6 27 5.2 0.1 2.1 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain zf-RING_2 PF13639.6 CRK20239.1 - 4.2e-09 36.6 8.0 6.4e-09 36.0 8.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 CRK20239.1 - 1.8e-05 24.9 7.8 5.7e-05 23.3 7.8 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CRK20239.1 - 0.00022 21.2 3.2 0.0004 20.4 3.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 CRK20239.1 - 0.00084 19.1 8.4 0.0024 17.7 8.6 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CRK20239.1 - 0.0017 18.1 4.8 0.0033 17.2 4.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CRK20239.1 - 0.0024 17.7 2.4 0.46 10.4 0.6 2.3 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 CRK20239.1 - 0.0052 16.6 5.7 0.0093 15.8 5.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 CRK20239.1 - 0.0083 16.2 4.2 0.041 14.0 4.0 2.0 1 1 1 2 2 2 1 Zinc-binding RING-finger zf-RING_UBOX PF13445.6 CRK20239.1 - 0.012 15.6 4.6 0.014 15.4 3.3 1.8 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_11 PF17123.5 CRK20239.1 - 0.019 14.7 6.4 0.042 13.6 6.4 1.6 1 1 0 1 1 1 0 RING-like zinc finger Zn-C2H2_12 PF18112.1 CRK20239.1 - 0.051 14.0 3.7 1.1 9.7 0.1 2.8 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain Rad50_zn_hook PF04423.14 CRK20239.1 - 0.11 12.3 1.1 3 7.7 0.1 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif UBZ_FAAP20 PF15750.5 CRK20239.1 - 0.16 12.0 2.4 4.4 7.3 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger Prok-RING_1 PF14446.6 CRK20239.1 - 0.38 10.7 3.8 11 6.1 0.9 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_5 PF14634.6 CRK20239.1 - 1.7 8.7 7.3 5.4 7.1 7.4 1.8 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_5 PF17121.5 CRK20239.1 - 1.9 8.4 8.0 7 6.6 8.1 1.9 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 CRK20239.1 - 2.8 7.8 6.7 9.9 6.1 6.8 1.8 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Hydrophobin_2 PF06766.11 CRK20241.1 - 3.7e-26 90.9 12.3 4.8e-26 90.5 12.3 1.1 1 0 0 1 1 1 1 Fungal hydrophobin PAP1 PF08601.10 CRK20242.1 - 2.2e-58 198.8 38.3 2.2e-58 198.8 38.3 3.7 3 1 0 3 3 3 1 Transcription factor PAP1 bZIP_1 PF00170.21 CRK20242.1 - 4.1e-10 39.6 10.9 3.2e-09 36.7 9.9 2.2 2 0 0 2 2 2 1 bZIP transcription factor SHE3 PF17078.5 CRK20242.1 - 0.0005 19.9 4.5 0.00088 19.0 4.5 1.3 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 bZIP_2 PF07716.15 CRK20242.1 - 0.013 15.5 12.6 0.034 14.2 10.7 2.5 2 1 0 2 2 2 0 Basic region leucine zipper bZIP_Maf PF03131.17 CRK20242.1 - 0.018 15.6 7.6 0.018 15.6 7.6 2.1 1 1 1 2 2 2 0 bZIP Maf transcription factor DUF812 PF05667.11 CRK20242.1 - 0.032 13.1 4.5 0.043 12.7 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) dsrm PF00035.26 CRK20242.1 - 0.086 13.6 0.1 0.2 12.4 0.1 1.5 1 0 0 1 1 1 0 Double-stranded RNA binding motif DUF4140 PF13600.6 CRK20242.1 - 0.26 11.8 1.6 0.63 10.5 1.6 1.7 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Csm1_N PF18504.1 CRK20242.1 - 0.53 10.7 4.7 0.41 11.0 0.3 2.2 1 1 1 2 2 2 0 Csm1 N-terminal domain UPF0242 PF06785.11 CRK20242.1 - 1.3 9.1 6.4 1.9 8.5 6.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus XhlA PF10779.9 CRK20242.1 - 1.6 9.0 4.2 2.6 8.3 4.2 1.3 1 0 0 1 1 1 0 Haemolysin XhlA DUF4407 PF14362.6 CRK20242.1 - 5.2 6.3 5.6 7.7 5.8 5.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) BSD PF03909.17 CRK20243.1 - 4e-19 68.4 0.1 7.6e-19 67.5 0.1 1.5 1 0 0 1 1 1 1 BSD domain Suf PF05843.14 CRK20243.1 - 0.0079 16.2 3.6 0.0079 16.2 3.6 2.0 1 1 1 2 2 2 1 Suppressor of forked protein (Suf) Sigma70_r2 PF04542.14 CRK20243.1 - 0.0089 15.8 0.3 0.058 13.2 0.0 2.3 2 0 0 2 2 2 1 Sigma-70 region 2 WGG PF10273.9 CRK20244.1 - 2.5e-27 95.4 0.3 4e-27 94.7 0.3 1.4 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 RRP7 PF12923.7 CRK20244.1 - 0.011 15.9 0.5 0.21 11.7 0.0 2.4 2 0 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain Abhydrolase_3 PF07859.13 CRK20245.1 - 4.2e-40 137.9 0.0 7.6e-30 104.3 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 CRK20245.1 - 1.2e-13 50.7 0.0 6.2e-13 48.4 0.0 1.9 2 0 0 2 2 2 1 Steryl acetyl hydrolase COesterase PF00135.28 CRK20245.1 - 0.0027 16.6 0.2 0.019 13.8 0.2 2.0 1 1 0 1 1 1 1 Carboxylesterase family Hydrolase_4 PF12146.8 CRK20245.1 - 0.073 12.3 0.0 0.18 11.1 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Cation_efflux PF01545.21 CRK20246.1 - 6.6e-26 91.3 16.3 8.1e-26 91.0 16.3 1.1 1 0 0 1 1 1 1 Cation efflux family MRP-L27 PF09809.9 CRK20246.1 - 5.7e-13 48.7 0.1 1.1e-12 47.7 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 ZT_dimer PF16916.5 CRK20246.1 - 3e-09 36.9 0.6 6.1e-09 35.9 0.6 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter DUF423 PF04241.15 CRK20246.1 - 0.7 10.1 3.2 3 8.1 0.6 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF423) DUF2104 PF09877.9 CRK20246.1 - 7.4 6.9 7.3 1 9.7 1.5 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2104) Zip PF02535.22 CRK20247.1 - 2.3e-45 155.3 0.0 1.4e-23 83.7 1.5 2.3 2 1 0 2 2 2 2 ZIP Zinc transporter DHDPS PF00701.22 CRK20248.1 - 2.9e-36 124.7 0.0 3.5e-36 124.4 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Glyco_hydro_88 PF07470.13 CRK20249.1 - 0.0068 15.5 0.4 0.011 14.9 0.4 1.3 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Ribosomal_L18 PF17135.4 CRK20258.1 - 4.2e-09 36.1 0.0 5.2e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e PI-PLC-Y PF00387.19 CRK20261.1 - 5.8e-39 133.0 0.0 6.8e-39 132.8 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain DnaJ PF00226.31 CRK20272.1 - 0.067 13.3 0.0 1.2 9.3 0.0 2.2 2 0 0 2 2 2 0 DnaJ domain Galactosyl_T PF01762.21 CRK20287.1 - 6.5e-10 39.2 0.3 7.9e-10 38.9 0.3 1.0 1 0 0 1 1 1 1 Galactosyltransferase Piwi PF02171.17 CRK20292.1 - 5.2e-14 52.2 0.0 7e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 Piwi domain ArgoL1 PF08699.10 CRK20292.1 - 1.4e-10 40.7 0.2 3.1e-10 39.6 0.2 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 CRK20292.1 - 1.3e-09 38.2 0.0 2.7e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 CRK20292.1 - 8.2e-06 26.0 0.3 0.038 14.3 0.3 2.5 2 0 0 2 2 2 2 Mid domain of argonaute Piwi PF02171.17 CRK20293.1 - 4.1e-54 183.9 0.0 5.4e-54 183.5 0.0 1.1 1 0 0 1 1 1 1 Piwi domain Inv-AAD PF18785.1 CRK20294.1 - 3.7e-59 198.2 0.1 4.2e-59 198.0 0.1 1.0 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 CRK20294.1 - 5.5e-09 35.8 0.1 8.6e-09 35.2 0.1 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.11 CRK20294.1 - 0.00016 21.6 0.0 0.00018 21.5 0.0 1.1 1 0 0 1 1 1 1 APOBEC-like N-terminal domain NAD1 PF18778.1 CRK20294.1 - 0.12 12.4 0.0 0.15 12.1 0.0 1.1 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 Glyco_hydro81C PF17652.1 CRK20295.1 - 2.1e-49 168.6 0.2 3.4e-49 168.0 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 CRK20295.1 - 1.4e-28 100.0 0.0 2.3e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain DnaJ PF00226.31 CRK20295.1 - 8.2e-22 77.1 1.8 1.7e-21 76.1 1.8 1.6 1 0 0 1 1 1 1 DnaJ domain Stn1 PF10451.9 CRK20295.1 - 1e-10 41.1 1.2 5.2e-06 25.6 0.1 2.5 2 0 0 2 2 2 2 Telomere regulation protein Stn1 PaaB PF06243.11 CRK20295.1 - 0.0029 17.8 0.4 0.0083 16.3 0.4 1.7 1 0 0 1 1 1 1 Phenylacetic acid degradation B Utp14 PF04615.13 CRK20297.1 - 2.3e-45 155.5 18.6 2.3e-45 155.5 18.6 2.2 1 1 1 2 2 2 1 Utp14 protein COX15-CtaA PF02628.15 CRK20298.1 - 1e-61 208.9 5.0 1.2e-61 208.5 5.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein YjbE PF11106.8 CRK20298.1 - 0.39 11.0 2.3 0.72 10.1 2.3 1.4 1 0 0 1 1 1 0 Exopolysaccharide production protein YjbE tRNA-synt_2 PF00152.20 CRK20299.1 - 1.4e-44 152.5 0.5 2e-44 151.9 0.5 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CRK20299.1 - 1.2e-10 41.2 0.1 2.6e-10 40.2 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CRK20299.1 - 0.0075 15.8 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) Furin-like_2 PF15913.5 CRK20299.1 - 0.18 11.9 0.0 13 6.0 0.0 2.6 3 0 0 3 3 3 0 Furin-like repeat, cysteine-rich ESCRT-II PF05871.12 CRK20301.1 - 7.2e-59 198.0 0.0 9.2e-59 197.7 0.0 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit PTCB-BRCT PF12738.7 CRK20302.1 - 1e-29 102.2 0.3 4.9e-21 74.4 0.2 4.7 5 0 0 5 5 5 3 twin BRCT domain RTT107_BRCT_5 PF16770.5 CRK20302.1 - 6.8e-29 99.7 0.0 2.8e-27 94.5 0.0 2.6 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT PF00533.26 CRK20302.1 - 1.3e-27 96.0 0.0 4.9e-12 46.1 0.0 6.4 7 1 0 7 7 7 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 CRK20302.1 - 6.4e-17 61.7 0.0 8.1e-06 26.2 0.1 4.9 6 0 0 6 6 6 3 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 CRK20302.1 - 8.4e-07 29.2 0.1 0.29 11.5 0.0 3.6 3 0 0 3 3 3 2 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 CRK20302.1 - 0.00059 19.9 0.1 0.13 12.3 0.0 3.3 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain adh_short PF00106.25 CRK20303.1 - 0.013 15.0 0.0 2.5 7.5 0.0 3.1 3 0 0 3 3 3 0 short chain dehydrogenase Glyco_hydro_115 PF15979.5 CRK20304.1 - 2.8e-133 444.6 0.0 3.6e-133 444.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 CRK20304.1 - 2.5e-25 89.3 0.0 4.6e-25 88.4 0.0 1.4 1 0 0 1 1 1 1 Gylcosyl hydrolase family 115 C-terminal domain MFS_1 PF07690.16 CRK20304.1 - 2.3e-14 53.1 36.1 4.6e-14 52.1 36.1 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily AKNA PF12443.8 CRK20307.1 - 0.0013 19.3 0.2 0.0047 17.6 0.0 2.0 2 0 0 2 2 2 1 AT-hook-containing transcription factor Vps36_ESCRT-II PF11605.8 CRK20307.1 - 0.05 13.8 0.0 0.17 12.1 0.0 1.8 1 1 1 2 2 2 0 Vacuolar protein sorting protein 36 Vps36 RraA-like PF03737.15 CRK20308.1 - 5.7e-27 94.7 0.2 7.3e-27 94.4 0.2 1.1 1 0 0 1 1 1 1 Aldolase/RraA Drf_GBD PF06371.13 CRK20309.1 - 4.7e-09 36.1 0.0 8.6e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain MFS_1 PF07690.16 CRK20310.1 - 7e-16 58.1 32.2 3e-14 52.7 32.0 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sigma_reg_N PF13800.6 CRK20310.1 - 0.034 14.4 0.4 0.23 11.8 0.0 2.5 2 0 0 2 2 2 0 Sigma factor regulator N-terminal DUF3619 PF12279.8 CRK20310.1 - 0.11 12.9 3.6 2.5 8.5 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3619) Glyco_hydro_31 PF01055.26 CRK20312.1 - 7.8e-154 513.1 0.7 1e-153 512.7 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 CRK20312.1 - 6.8e-37 126.2 0.0 1.3e-36 125.3 0.0 1.5 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 CRK20312.1 - 7e-16 58.3 1.4 2.5e-15 56.5 1.4 2.1 1 0 0 1 1 1 1 Galactose mutarotase-like Ceramidase_alk PF04734.13 CRK20313.1 - 1.9e-213 709.7 0.0 2.2e-213 709.5 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 CRK20313.1 - 8.5e-58 194.9 0.0 1.3e-57 194.3 0.0 1.3 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal DUF2014 PF09427.10 CRK20314.1 - 2.2e-114 381.3 9.3 3.6e-114 380.6 9.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.26 CRK20314.1 - 9.9e-06 25.4 0.0 2e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain CcmD PF04995.14 CRK20315.1 - 0.0002 21.4 0.0 0.00043 20.3 0.0 1.6 1 0 0 1 1 1 1 Heme exporter protein D (CcmD) TMEM154 PF15102.6 CRK20315.1 - 1.1 9.1 2.9 0.59 10.0 0.1 1.9 2 0 0 2 2 2 0 TMEM154 protein family Pkinase PF00069.25 CRK20316.1 - 5.8e-13 48.8 0.0 1.1e-12 47.9 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK20316.1 - 6e-09 35.6 0.0 2.1e-08 33.8 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CRK20316.1 - 0.00047 19.6 0.0 0.00077 18.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CRK20316.1 - 0.015 14.6 0.0 0.018 14.4 0.0 1.1 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 CRK20316.1 - 0.017 15.0 0.5 0.051 13.5 0.3 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 CRK20316.1 - 0.053 13.1 0.0 0.076 12.6 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.20 CRK20316.1 - 0.09 12.3 0.1 0.27 10.8 0.0 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase Amidohydro_2 PF04909.14 CRK20318.1 - 0.00048 20.0 0.0 0.00061 19.7 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.20 CRK20318.1 - 0.026 13.8 0.0 0.03 13.6 0.0 1.1 1 0 0 1 1 1 0 Amidohydrolase family Pribosyltran_N PF13793.6 CRK20321.1 - 1.5e-31 108.7 0.0 2.3e-31 108.1 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 CRK20321.1 - 0.00062 19.9 0.0 0.00098 19.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 CRK20321.1 - 0.0055 16.2 0.0 0.013 15.0 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DUF2007 PF09413.10 CRK20321.1 - 0.094 12.9 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative prokaryotic signal transducing protein RhoGEF PF00621.20 CRK20323.1 - 2.2e-18 67.1 0.4 3.4e-18 66.5 0.4 1.3 1 0 0 1 1 1 1 RhoGEF domain Mer2 PF09074.10 CRK20323.1 - 0.051 13.4 0.2 0.068 13.0 0.2 1.3 1 1 0 1 1 1 0 Mer2 Ribonuc_red_lgC PF02867.15 CRK20326.1 - 1.2e-48 166.0 0.0 1.3e-48 165.8 0.0 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribosomal_L6 PF00347.23 CRK20337.1 - 0.0035 18.0 0.1 0.0041 17.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L6 HEAT_EZ PF13513.6 CRK20353.1 - 0.00033 21.1 0.2 0.0014 19.0 0.0 2.1 2 1 1 3 3 3 1 HEAT-like repeat DRIM PF07539.12 CRK20353.1 - 0.0034 15.8 0.0 0.0037 15.6 0.0 1.0 1 0 0 1 1 1 1 Down-regulated in metastasis HEAT PF02985.22 CRK20353.1 - 0.022 15.0 0.1 0.2 12.0 0.0 2.7 2 1 0 2 2 2 0 HEAT repeat Arm PF00514.23 CRK20353.1 - 0.16 12.1 0.0 0.58 10.3 0.0 2.0 1 0 0 1 1 1 0 Armadillo/beta-catenin-like repeat Cpn60_TCP1 PF00118.24 CRK20360.1 - 5e-40 137.6 0.3 5.4e-40 137.4 0.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Fungal_trans PF04082.18 CRK20361.1 - 4.6e-14 52.1 0.9 6.5e-14 51.6 0.9 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK20361.1 - 0.00014 21.9 11.7 0.00031 20.8 11.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AMP-binding PF00501.28 CRK20362.1 - 8.5e-63 212.4 0.0 7.7e-61 205.9 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 CRK20362.1 - 5e-11 43.4 0.4 1.1e-10 42.3 0.4 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain p450 PF00067.22 CRK20363.1 - 2.7e-66 224.2 0.0 6.4e-66 223.0 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Scytalone_dh PF02982.14 CRK20364.1 - 1.8e-89 297.6 0.4 2.8e-89 297.0 0.4 1.3 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.6 CRK20364.1 - 0.00011 22.3 0.1 0.00024 21.2 0.1 1.5 1 0 0 1 1 1 1 SnoaL-like domain Trep_Strep PF09605.10 CRK20364.1 - 0.026 14.5 0.3 0.026 14.5 0.3 1.7 2 0 0 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) Cyt-b5 PF00173.28 CRK20366.1 - 7.2e-13 48.5 0.0 9.5e-13 48.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TrbC PF04956.13 CRK20367.1 - 0.64 10.3 5.1 14 6.0 0.1 2.4 2 0 0 2 2 2 0 TrbC/VIRB2 family FSA_C PF10479.9 CRK20367.1 - 3.1 5.8 9.3 4 5.5 9.3 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus ADH_N PF08240.12 CRK20368.1 - 2.2e-25 88.7 3.9 3.7e-25 87.9 3.9 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CRK20368.1 - 1.3e-18 67.3 0.0 2e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CRK20368.1 - 6e-09 37.1 0.0 1.1e-08 36.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 CRK20368.1 - 0.003 16.9 0.0 0.005 16.2 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 CRK20368.1 - 0.014 14.7 0.3 0.024 14.0 0.3 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Aldo_ket_red PF00248.21 CRK20369.1 - 7.8e-62 209.1 0.0 9.4e-62 208.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family GFA PF04828.14 CRK20370.1 - 3.2e-22 78.7 1.1 4.8e-22 78.1 1.1 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme RNA_POL_M_15KD PF02150.16 CRK20370.1 - 0.019 14.9 0.1 0.019 14.9 0.1 2.0 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit DUF3818 PF12825.7 CRK20372.1 - 1.9e-49 168.6 0.0 5.5e-33 114.4 0.2 2.1 1 1 1 2 2 2 2 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 CRK20372.1 - 7.2e-42 142.4 0.0 1.4e-41 141.6 0.0 1.5 1 0 0 1 1 1 1 PX-associated RAP1 PF07218.11 CRK20372.1 - 0.33 9.2 7.0 0.59 8.3 7.0 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) NAD_binding_2 PF03446.15 CRK20373.1 - 3.8e-23 82.4 0.2 6.8e-23 81.6 0.2 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 CRK20373.1 - 2.1e-09 37.7 0.1 4e-09 36.8 0.1 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.20 CRK20373.1 - 0.0031 17.6 0.0 0.0061 16.6 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Cation_efflux PF01545.21 CRK20374.1 - 4.2e-15 56.0 5.3 5.9e-15 55.5 5.3 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 CRK20374.1 - 3.7e-11 43.0 0.7 7.5e-11 42.0 0.7 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter PilJ PF13675.6 CRK20374.1 - 0.096 12.7 0.3 4.6 7.3 0.2 2.9 3 0 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF4291 PF14124.6 CRK20375.1 - 3.2e-64 216.1 0.0 6.8e-64 215.1 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4291) Glyco_hydro_47 PF01532.20 CRK20376.1 - 9.6e-144 479.7 0.0 1.6e-143 478.9 0.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_61 PF03443.14 CRK20377.1 - 1.3e-48 165.6 0.0 1.7e-48 165.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Aldo_ket_red PF00248.21 CRK20379.1 - 4.1e-14 52.5 0.0 4.5e-14 52.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AtuA PF07287.11 CRK20380.1 - 1.5e-59 201.5 0.1 2.1e-59 201.0 0.1 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA CFEM PF05730.11 CRK20380.1 - 0.0054 16.8 10.2 0.012 15.7 10.2 1.5 1 0 0 1 1 1 1 CFEM domain PGF-CTERM PF18204.1 CRK20380.1 - 0.14 12.1 0.5 0.5 10.4 0.5 1.9 1 0 0 1 1 1 0 PGF-CTERM motif Sugar_tr PF00083.24 CRK20381.1 - 1.2e-61 209.0 19.0 2.6e-53 181.5 9.9 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CRK20381.1 - 3.5e-23 82.1 25.0 2.1e-22 79.6 14.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 CRK20381.1 - 0.00014 20.6 1.5 0.00014 20.6 1.5 2.8 2 2 0 2 2 2 1 MFS/sugar transport protein ATP_synt_H PF05493.13 CRK20381.1 - 0.15 12.5 11.5 0.067 13.7 5.2 2.9 2 0 0 2 2 2 0 ATP synthase subunit H Tweety PF04906.13 CRK20381.1 - 0.21 10.2 1.5 0.32 9.6 1.5 1.2 1 0 0 1 1 1 0 Tweety DUF1077 PF06417.12 CRK20382.1 - 1.9e-55 185.9 8.4 4e-48 162.3 4.6 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1077) 7kD_DNA_binding PF02294.18 CRK20382.1 - 0.12 12.5 1.5 18 5.5 0.0 2.6 3 0 0 3 3 3 0 7kD DNA-binding domain Adaptin_N PF01602.20 CRK20383.1 - 1.6e-124 416.4 10.0 2.1e-124 416.0 8.2 1.7 2 0 0 2 2 2 1 Adaptin N terminal region Cnd1 PF12717.7 CRK20383.1 - 5.2e-55 185.9 9.2 2.9e-54 183.5 0.2 3.4 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CRK20383.1 - 1e-14 54.6 12.9 5.4e-09 36.3 0.5 4.8 5 0 0 5 5 5 3 HEAT repeats HEAT PF02985.22 CRK20383.1 - 3.7e-12 45.4 2.1 0.00011 22.1 0.0 5.7 6 0 0 6 6 6 3 HEAT repeat CLASP_N PF12348.8 CRK20383.1 - 0.00016 21.3 1.3 0.14 11.7 0.0 3.1 3 0 0 3 3 3 2 CLASP N terminal HEAT_EZ PF13513.6 CRK20383.1 - 0.00068 20.1 11.6 4.8 7.8 0.0 6.8 7 0 0 7 7 7 1 HEAT-like repeat RTP1_C1 PF10363.9 CRK20383.1 - 0.0007 19.7 1.1 0.096 12.9 0.0 3.7 2 1 1 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 CRK20383.1 - 0.0051 16.8 3.0 1.7 8.8 0.1 4.8 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 CRK20383.1 - 0.072 13.1 0.7 17 5.5 0.0 4.2 5 1 0 5 5 5 0 Spinocerebellar ataxia type 10 protein domain Rad60-SLD_2 PF13881.6 CRK20384.1 - 5.9e-12 45.7 0.0 1.4e-11 44.5 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 CRK20384.1 - 0.00037 20.2 0.0 0.00067 19.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 CRK20384.1 - 0.0045 17.5 0.0 0.012 16.2 0.0 1.7 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain TFIIA PF03153.13 CRK20384.1 - 0.78 9.7 3.2 0.79 9.7 3.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit UMP1 PF05348.11 CRK20385.1 - 4.8e-40 136.5 0.0 6.5e-40 136.0 0.0 1.2 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Adaptin_N PF01602.20 CRK20386.1 - 3.1e-64 217.4 1.1 3.6e-64 217.2 1.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Rad60-SLD_2 PF13881.6 CRK20386.1 - 2.1e-11 43.9 0.0 4.9e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like HEAT_2 PF13646.6 CRK20386.1 - 7e-06 26.4 0.5 0.11 12.9 0.1 2.6 2 0 0 2 2 2 2 HEAT repeats ubiquitin PF00240.23 CRK20386.1 - 0.001 18.8 0.0 0.002 17.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 CRK20386.1 - 0.014 15.9 0.0 0.038 14.6 0.0 1.7 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Arm PF00514.23 CRK20386.1 - 0.055 13.5 0.6 1.4 9.1 0.1 3.0 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat UMP1 PF05348.11 CRK20387.1 - 1.4e-39 135.0 0.0 1.9e-39 134.6 0.0 1.2 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Chitin_synth_1 PF01644.17 CRK20388.1 - 6e-77 257.2 0.5 2.4e-76 255.2 0.1 2.0 2 0 0 2 2 2 1 Chitin synthase Chitin_synth_1N PF08407.11 CRK20388.1 - 2.2e-55 184.5 3.1 1e-26 92.7 0.2 2.5 2 0 0 2 2 2 2 Chitin synthase N-terminal ABC_tran PF00005.27 CRK20388.1 - 1.6e-30 106.4 0.0 1.3e-08 35.4 0.0 4.4 3 3 0 3 3 3 3 ABC transporter Chitin_synth_2 PF03142.15 CRK20388.1 - 2.2e-22 79.4 7.2 8.5e-20 70.8 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase SbcCD_C PF13558.6 CRK20388.1 - 6.1e-12 45.6 0.8 0.0024 18.1 0.0 3.9 4 0 0 4 4 4 2 Putative exonuclease SbcCD, C subunit Glyco_trans_2_3 PF13632.6 CRK20388.1 - 8e-08 32.4 3.1 3.8e-07 30.2 3.1 2.3 1 1 0 1 1 1 1 Glycosyl transferase family group 2 AAA_23 PF13476.6 CRK20388.1 - 2.3e-07 31.5 3.0 0.16 12.5 0.2 3.3 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 CRK20388.1 - 2.4e-06 27.2 0.1 0.63 9.8 0.0 3.6 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_21 PF13304.6 CRK20388.1 - 7.2e-06 26.0 6.4 0.29 10.9 0.0 4.6 5 0 0 5 5 5 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 CRK20388.1 - 9.3e-05 22.7 0.0 5 7.4 0.0 3.9 3 0 0 3 3 3 1 AAA domain Ploopntkinase1 PF18748.1 CRK20388.1 - 0.00042 19.9 0.0 1.5 8.3 0.0 2.7 3 0 0 3 3 3 2 P-loop Nucleotide Kinase1 AAA_24 PF13479.6 CRK20388.1 - 0.0009 19.0 0.0 16 5.2 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 CRK20388.1 - 0.0031 17.7 0.4 9.9 6.3 0.0 3.4 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 CRK20388.1 - 0.0034 17.7 0.2 12 6.3 0.0 3.8 4 0 0 4 4 3 0 RNA helicase AAA PF00004.29 CRK20388.1 - 0.0048 17.3 0.1 6.7 7.1 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CRK20388.1 - 0.011 16.1 0.0 12 6.3 0.0 3.1 3 0 0 3 3 3 0 AAA ATPase domain DUF87 PF01935.17 CRK20388.1 - 0.013 15.7 0.0 9.3 6.3 0.0 2.7 2 0 0 2 2 2 0 Helicase HerA, central domain ATP-synt_ab PF00006.25 CRK20388.1 - 0.015 15.0 0.0 6.5 6.3 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain SMC_N PF02463.19 CRK20388.1 - 0.041 13.3 0.2 12 5.2 0.0 2.5 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 CRK20388.1 - 0.071 13.7 0.1 74 3.9 0.0 3.4 3 0 0 3 3 3 0 AAA domain ATP_bind_1 PF03029.17 CRK20388.1 - 0.084 12.6 0.0 21 4.8 0.0 2.7 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_13 PF13166.6 CRK20388.1 - 0.12 11.0 0.0 13 4.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain TetR_C_28 PF17937.1 CRK20388.1 - 0.15 12.5 0.4 24 5.5 0.1 2.8 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain AAA_7 PF12775.7 CRK20388.1 - 0.17 11.4 0.0 54 3.2 0.0 3.1 3 0 0 3 3 3 0 P-loop containing dynein motor region SRP54 PF00448.22 CRK20388.1 - 0.18 11.4 0.0 26 4.4 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain cobW PF02492.19 CRK20388.1 - 0.26 10.8 0.1 31 4.1 0.0 2.5 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain ECH_1 PF00378.20 CRK20389.1 - 5.5e-37 127.4 0.0 1.4e-24 86.8 0.1 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CRK20389.1 - 1e-16 61.4 0.1 3.7e-16 59.5 0.1 1.9 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 CRK20389.1 - 0.064 13.2 0.1 0.96 9.4 0.0 2.2 2 0 0 2 2 2 0 Peptidase family S49 MFS_1 PF07690.16 CRK20390.1 - 1.4e-07 30.8 29.6 2.9e-06 26.5 21.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TssN PF17555.2 CRK20390.1 - 3.2 7.1 8.1 1.5 8.2 0.4 2.1 2 0 0 2 2 2 0 Type VI secretion system, TssN ELO PF01151.18 CRK20395.1 - 1.5e-07 31.3 0.0 1.6e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family HEAT PF02985.22 CRK20396.1 - 3.9e-06 26.6 0.0 0.00052 20.1 0.0 3.1 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.6 CRK20396.1 - 1.1e-05 25.7 0.1 0.00016 22.0 0.0 2.3 2 0 0 2 2 2 1 HEAT repeats HEAT_EZ PF13513.6 CRK20396.1 - 0.04 14.4 0.1 2.1 8.9 0.0 2.7 2 0 0 2 2 2 0 HEAT-like repeat TAF6_C PF07571.13 CRK20396.1 - 0.078 13.3 0.0 19 5.7 0.0 3.1 2 1 1 3 3 3 0 TAF6 C-terminal HEAT repeat domain SMC_N PF02463.19 CRK20397.1 - 2.8e-37 128.3 0.5 4.1e-37 127.8 0.5 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CRK20397.1 - 8.5e-21 75.4 4.7 1.5e-20 74.6 4.7 1.4 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 CRK20397.1 - 1.8e-12 47.6 6.4 3.1e-11 43.6 6.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 CRK20397.1 - 2.6e-07 30.8 0.4 3.3e-07 30.4 0.3 1.5 1 1 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CRK20397.1 - 0.00027 20.6 0.0 0.00047 19.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 CRK20397.1 - 0.015 15.8 0.4 0.027 15.0 0.4 1.8 1 1 0 1 1 1 0 ABC transporter DUF724 PF05266.14 CRK20397.1 - 0.41 10.5 3.6 0.82 9.5 3.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Ion_trans_2 PF07885.16 CRK20413.1 - 1.4e-14 53.8 6.7 1.9e-14 53.4 6.7 1.2 1 0 0 1 1 1 1 Ion channel DUF2264 PF10022.9 CRK20440.1 - 3.3e-47 161.3 0.0 3.7e-47 161.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) AIM24 PF01987.17 CRK20442.1 - 2.1e-48 164.8 0.0 3.4e-48 164.1 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 MFS_1 PF07690.16 CRK20442.1 - 3.9e-12 45.8 22.4 6.2e-12 45.1 22.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK20442.1 - 0.00011 21.2 11.9 0.00019 20.4 11.9 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 CRK20442.1 - 0.00024 20.1 7.2 0.0007 18.6 7.3 1.7 1 1 0 1 1 1 1 MFS_1 like family MFS_2 PF13347.6 CRK20442.1 - 0.0013 17.4 9.9 0.002 16.8 9.9 1.2 1 0 0 1 1 1 1 MFS/sugar transport protein AFOR_N PF02730.15 CRK20442.1 - 0.28 11.0 2.0 10 6.0 0.0 2.5 2 0 0 2 2 2 0 Aldehyde ferredoxin oxidoreductase, N-terminal domain Kinesin PF00225.23 CRK20444.1 - 1.9e-51 175.0 0.0 3.7e-51 174.0 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CRK20444.1 - 5.5e-22 78.3 0.0 2.3e-21 76.3 0.0 2.0 2 0 0 2 2 2 1 Microtubule binding HHH_5 PF14520.6 CRK20444.1 - 0.0024 18.4 0.0 0.5 11.0 0.0 2.8 2 0 0 2 2 2 1 Helix-hairpin-helix domain DUF87 PF01935.17 CRK20444.1 - 0.0063 16.6 2.0 2.4 8.2 0.0 3.3 3 0 0 3 3 3 1 Helicase HerA, central domain AAA_22 PF13401.6 CRK20444.1 - 0.013 15.8 3.9 12 6.2 0.0 4.1 4 0 0 4 4 4 0 AAA domain Zeta_toxin PF06414.12 CRK20444.1 - 0.037 13.3 0.6 0.14 11.4 0.0 2.3 3 0 0 3 3 3 0 Zeta toxin TrwB_AAD_bind PF10412.9 CRK20444.1 - 0.058 12.3 0.0 3 6.6 0.0 2.6 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain FtsK_SpoIIIE PF01580.18 CRK20444.1 - 0.067 12.5 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family HHH_3 PF12836.7 CRK20444.1 - 0.092 13.0 0.0 0.3 11.4 0.0 1.8 1 1 0 1 1 1 0 Helix-hairpin-helix motif AAA PF00004.29 CRK20444.1 - 0.32 11.4 1.8 12 6.3 0.0 3.2 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) HATPase_c PF02518.26 CRK20447.1 - 5.4e-22 78.4 0.0 1.1e-21 77.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 CRK20447.1 - 1.4e-21 76.7 0.9 2.6e-21 75.9 0.4 1.7 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 CRK20447.1 - 4.3e-06 26.7 2.0 4.7e-06 26.6 0.1 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 CRK20447.1 - 1.2e-05 25.5 0.0 0.0022 18.2 0.0 2.9 2 0 0 2 2 2 1 PAS fold PAS PF00989.25 CRK20447.1 - 0.0029 17.6 0.0 0.0068 16.4 0.0 1.7 1 0 0 1 1 1 1 PAS fold Colipase PF01114.18 CRK20447.1 - 0.063 13.0 0.2 0.15 11.8 0.2 1.6 1 0 0 1 1 1 0 Colipase, N-terminal domain FAD_binding_4 PF01565.23 CRK20450.1 - 3.8e-19 68.8 0.2 8e-19 67.8 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 CRK20450.1 - 1.2e-09 38.1 0.1 2.9e-09 36.9 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like ALO PF04030.14 CRK20450.1 - 0.014 15.3 0.1 0.03 14.1 0.1 1.5 1 0 0 1 1 1 0 D-arabinono-1,4-lactone oxidase Cytokin-bind PF09265.10 CRK20450.1 - 0.11 11.8 0.1 0.19 11.1 0.1 1.3 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding NAD_binding_4 PF07993.12 CRK20452.1 - 3.6e-44 150.9 0.1 6.4e-44 150.1 0.1 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 CRK20452.1 - 6.2e-39 133.8 0.0 9.8e-39 133.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AAA_33 PF13671.6 CRK20452.1 - 2.2e-11 44.1 0.0 5.5e-11 42.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain Epimerase PF01370.21 CRK20452.1 - 7.9e-11 41.9 0.0 2.1e-10 40.5 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 CRK20452.1 - 4.8e-10 39.6 0.2 4.4e-09 36.6 0.0 2.7 3 0 0 3 3 3 1 Phosphopantetheine attachment site SKI PF01202.22 CRK20452.1 - 5.2e-09 36.4 0.0 1.1e-08 35.3 0.0 1.5 1 0 0 1 1 1 1 Shikimate kinase KR PF08659.10 CRK20452.1 - 1.7e-06 28.1 0.6 6.4e-06 26.2 0.6 2.1 1 0 0 1 1 1 1 KR domain AAA_18 PF13238.6 CRK20452.1 - 2.7e-05 24.7 0.0 7.5e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 CRK20452.1 - 5.2e-05 23.2 0.1 0.00023 21.1 0.0 2.1 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein APS_kinase PF01583.20 CRK20452.1 - 9.9e-05 22.3 0.0 0.00021 21.2 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_17 PF13207.6 CRK20452.1 - 0.00013 22.4 0.0 0.00033 21.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 CRK20452.1 - 0.0011 18.3 0.1 0.0066 15.8 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_PrkA PF08298.11 CRK20452.1 - 0.0042 16.0 0.0 0.0073 15.3 0.0 1.2 1 0 0 1 1 1 1 PrkA AAA domain Cytidylate_kin PF02224.18 CRK20452.1 - 0.0061 16.3 0.0 0.015 15.0 0.0 1.7 1 0 0 1 1 1 1 Cytidylate kinase AAA_16 PF13191.6 CRK20452.1 - 0.0074 16.7 0.4 0.048 14.0 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain 3Beta_HSD PF01073.19 CRK20452.1 - 0.021 13.9 0.0 0.1 11.6 0.0 1.9 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family T2SSE PF00437.20 CRK20452.1 - 0.022 13.8 0.3 0.15 11.0 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein Semialdhyde_dh PF01118.24 CRK20452.1 - 0.023 15.1 0.0 0.063 13.7 0.0 1.8 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain AAA PF00004.29 CRK20452.1 - 0.024 15.1 0.0 0.1 13.1 0.0 2.1 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 CRK20452.1 - 0.026 14.1 0.3 0.16 11.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain Cytidylate_kin2 PF13189.6 CRK20452.1 - 0.033 14.3 0.3 0.11 12.6 0.0 2.0 2 0 0 2 2 2 0 Cytidylate kinase-like family ABC_tran PF00005.27 CRK20452.1 - 0.042 14.4 0.0 0.11 13.0 0.0 1.7 1 0 0 1 1 1 0 ABC transporter CoaE PF01121.20 CRK20452.1 - 0.074 12.7 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Dephospho-CoA kinase dNK PF01712.19 CRK20452.1 - 0.083 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Deoxynucleoside kinase AAA_22 PF13401.6 CRK20452.1 - 0.084 13.1 0.0 0.62 10.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.10 CRK20452.1 - 0.13 11.7 0.1 0.71 9.3 0.0 2.2 2 1 1 3 3 3 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 CRK20452.1 - 0.13 12.2 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase NmrA PF05368.13 CRK20452.1 - 0.15 11.6 0.1 0.33 10.5 0.1 1.5 1 0 0 1 1 1 0 NmrA-like family AAA_29 PF13555.6 CRK20452.1 - 0.16 11.7 0.0 0.49 10.2 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain DapB_N PF01113.20 CRK20452.1 - 0.16 12.1 0.0 0.8 9.8 0.0 2.2 2 0 0 2 2 1 0 Dihydrodipicolinate reductase, N-terminus Aldo_ket_red PF00248.21 CRK20454.1 - 4.5e-47 160.7 0.0 5e-46 157.2 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Fungal_trans PF04082.18 CRK20455.1 - 7.3e-28 97.3 0.0 1.1e-27 96.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK20455.1 - 4.5e-08 33.1 8.3 7.7e-08 32.3 8.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 CRK20458.1 - 1.8e-33 116.0 19.3 2.2e-33 115.7 19.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily zf-CCCH PF00642.24 CRK20458.1 - 3e-11 42.9 8.5 9.1e-06 25.5 2.0 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CRK20458.1 - 1.4e-10 40.9 16.5 3.3e-05 23.8 3.5 2.7 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 CRK20458.1 - 7.2e-09 35.2 15.4 1.7e-05 24.5 2.9 2.8 3 0 0 3 3 3 2 CCCH-type zinc finger Torus PF16131.5 CRK20458.1 - 7.6e-09 36.2 6.1 9.6e-05 23.0 0.5 2.3 1 1 1 2 2 2 2 Torus domain zf-CCCH_3 PF15663.5 CRK20458.1 - 3.3e-05 24.1 1.3 6.4e-05 23.1 1.3 1.4 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 CRK20458.1 - 0.00035 20.9 15.8 0.077 13.5 5.4 2.6 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Acyltransferase PF01553.21 CRK20460.1 - 3.2e-33 114.2 0.0 5e-33 113.6 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase RIO1 PF01163.22 CRK20461.1 - 5.2e-67 225.1 1.0 7.9e-67 224.5 0.0 1.8 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 CRK20461.1 - 0.0033 17.4 4.1 0.43 10.5 0.1 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family YL1 PF05764.13 CRK20461.1 - 3.9 7.5 31.0 6 6.9 18.9 2.3 2 0 0 2 2 2 0 YL1 nuclear protein Glyco_hydro_61 PF03443.14 CRK20463.1 - 1.1e-58 198.6 0.0 1.6e-58 198.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 RrnaAD PF00398.20 CRK20465.1 - 0.00021 20.4 0.0 0.00037 19.7 0.0 1.4 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase c-SKI_SMAD_bind PF08782.10 CRK20469.1 - 0.075 13.3 0.1 0.13 12.5 0.1 1.3 1 0 0 1 1 1 0 c-SKI Smad4 binding domain EPF PF17181.4 CRK20469.1 - 0.11 12.6 0.4 0.17 11.9 0.4 1.3 1 0 0 1 1 1 0 Epidermal patterning factor proteins Fer4 PF00037.27 CRK20469.1 - 0.15 11.9 2.7 0.25 11.2 2.7 1.3 1 0 0 1 1 1 0 4Fe-4S binding domain Glyco_hydro_18 PF00704.28 CRK20471.1 - 2e-17 63.9 0.1 4.1e-17 62.9 0.1 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 PhnG PF06754.12 CRK20474.1 - 0.017 15.1 0.0 0.02 14.8 0.0 1.2 1 1 0 1 1 1 0 Phosphonate metabolism protein PhnG HTH_35 PF13693.6 CRK20474.1 - 0.11 12.6 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Mito_carr PF00153.27 CRK20475.1 - 9.7e-52 172.9 2.7 7.1e-21 73.9 0.1 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein PCMT PF01135.19 CRK20480.1 - 3.3e-52 177.3 0.0 3.9e-52 177.1 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 CRK20480.1 - 1.3e-06 28.3 0.0 2.2e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK20480.1 - 7e-05 23.5 0.0 0.00011 22.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 CRK20480.1 - 0.00022 21.3 0.0 0.00033 20.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CRK20480.1 - 0.0083 16.0 0.0 0.0097 15.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CRK20480.1 - 0.0088 16.7 0.0 0.014 16.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CRK20480.1 - 0.019 14.3 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Abhydrolase_6 PF12697.7 CRK20482.1 - 1.9e-06 28.7 8.7 1.9e-06 28.7 8.7 1.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family Thioesterase PF00975.20 CRK20482.1 - 6e-06 26.5 0.0 1.4e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.20 CRK20482.1 - 2.5e-05 24.1 0.1 4.8e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 CRK20482.1 - 0.063 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase Glyco_hydro_47 PF01532.20 CRK20484.1 - 4.3e-164 546.8 0.0 4.2e-131 438.0 0.0 2.0 2 0 0 2 2 2 2 Glycosyl hydrolase family 47 Alpha-L-AF_C PF06964.12 CRK20486.1 - 4.8e-20 72.3 0.0 7.7e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain Sugar_tr PF00083.24 CRK20488.1 - 2e-96 323.6 18.5 2.3e-96 323.4 18.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK20488.1 - 7e-29 100.8 24.4 3.9e-22 78.7 9.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 CRK20488.1 - 2.3e-07 29.7 15.7 0.00048 18.8 3.0 2.4 2 1 0 2 2 2 2 MFS/sugar transport protein zf-C2H2_2 PF12756.7 CRK20490.1 - 1.1e-26 93.0 0.9 2e-26 92.2 0.9 1.3 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) EthD PF07110.11 CRK20491.1 - 6.8e-23 81.6 0.2 1.3e-22 80.7 0.2 1.5 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 CRK20491.1 - 1.1e-05 25.9 0.0 2e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase DUF835 PF05763.12 CRK20491.1 - 0.05 13.3 0.0 0.071 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF835) SAP18 PF06487.12 CRK20491.1 - 0.24 11.6 0.8 5.2 7.3 0.1 2.2 1 1 1 2 2 2 0 Sin3 associated polypeptide p18 (SAP18) NAD_binding_8 PF13450.6 CRK20493.1 - 1.8e-11 44.1 0.1 3.7e-11 43.1 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 CRK20493.1 - 2.8e-09 36.9 0.8 6.3e-09 35.7 0.4 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 CRK20493.1 - 2.8e-08 33.5 0.0 9.7e-07 28.4 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 CRK20493.1 - 1.8e-07 30.6 3.8 1.8e-07 30.6 3.8 1.7 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_2 PF07992.14 CRK20493.1 - 2.2e-07 30.4 0.2 9.8e-07 28.3 0.2 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CRK20493.1 - 3.5e-07 29.8 0.1 5.4e-07 29.2 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CRK20493.1 - 6.2e-07 28.5 3.1 1.1e-06 27.6 3.1 1.4 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 CRK20493.1 - 5.3e-06 26.2 0.4 2.8e-05 23.9 0.7 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 CRK20493.1 - 9.9e-06 26.0 2.4 0.00092 19.7 1.3 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CRK20493.1 - 2.7e-05 23.6 0.0 3.5e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 CRK20493.1 - 0.00027 20.1 1.6 0.00039 19.6 1.6 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.17 CRK20493.1 - 0.00047 19.5 0.9 0.00085 18.6 0.9 1.3 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.21 CRK20493.1 - 0.00056 19.3 0.9 0.007 15.7 0.7 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain IlvN PF07991.12 CRK20493.1 - 0.0054 16.3 0.2 0.0092 15.6 0.2 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_7 PF13241.6 CRK20493.1 - 0.057 13.9 0.1 0.1 13.1 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Lycopene_cycl PF05834.12 CRK20493.1 - 0.092 11.8 0.2 0.14 11.1 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein MCRA PF06100.11 CRK20493.1 - 0.22 10.3 0.1 0.3 9.8 0.1 1.1 1 0 0 1 1 1 0 MCRA family Trp_halogenase PF04820.14 CRK20493.1 - 0.39 9.5 1.5 0.72 8.6 1.5 1.4 1 0 0 1 1 1 0 Tryptophan halogenase PNPase_C PF12111.8 CRK20493.1 - 5.6 6.5 6.2 2.2 7.8 0.1 2.6 2 0 0 2 2 2 0 Polyribonucleotide phosphorylase C terminal Abhydrolase_3 PF07859.13 CRK20494.1 - 5.6e-09 36.2 0.6 2.7e-07 30.6 0.6 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CRK20494.1 - 4.4e-08 32.9 0.0 1.2e-07 31.4 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 CRK20494.1 - 1.3e-07 31.4 0.0 2.7e-06 27.1 0.0 2.7 2 1 0 2 2 2 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 CRK20494.1 - 3.9e-05 23.0 0.0 0.21 10.8 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CRK20494.1 - 5.1e-05 23.0 0.1 0.028 14.1 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF829 PF05705.14 CRK20494.1 - 0.0048 16.8 0.0 0.0055 16.6 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) YjeF_N PF03853.15 CRK20494.1 - 0.059 13.3 0.1 0.16 11.8 0.0 1.8 2 0 0 2 2 2 0 YjeF-related protein N-terminus Ser_hydrolase PF06821.13 CRK20494.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase LIP PF03583.14 CRK20494.1 - 0.13 11.5 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Secretory lipase FSH1 PF03959.13 CRK20494.1 - 0.21 11.2 0.0 0.29 10.8 0.0 1.1 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 CRK20494.1 - 0.79 10.3 7.8 28 5.2 7.8 2.1 1 1 0 1 1 1 0 Alpha/beta hydrolase family MFS_1 PF07690.16 CRK20496.1 - 4.8e-39 134.3 34.2 1.2e-33 116.6 24.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK20496.1 - 5.1e-11 42.1 17.7 1.2e-10 40.9 17.7 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter Shisa PF13908.6 CRK20498.1 - 0.0023 18.2 0.0 0.0023 18.2 0.0 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Adeno_E3_CR2 PF02439.15 CRK20498.1 - 0.013 15.2 6.5 0.021 14.6 6.5 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 TMEM132D_C PF15706.5 CRK20498.1 - 0.046 13.5 0.3 0.063 13.1 0.3 1.2 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term EphA2_TM PF14575.6 CRK20498.1 - 0.056 14.3 0.0 0.066 14.1 0.0 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM52 PF14979.6 CRK20498.1 - 0.13 12.2 1.1 0.16 11.9 1.1 1.1 1 0 0 1 1 1 0 Transmembrane 52 Rax2 PF12768.7 CRK20498.1 - 0.15 11.5 0.0 0.18 11.2 0.0 1.1 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Mid2 PF04478.12 CRK20498.1 - 0.17 11.7 0.1 0.23 11.3 0.1 1.1 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor GMC_oxred_C PF05199.13 CRK20500.1 - 1.7e-21 77.2 0.3 6e-21 75.5 0.1 2.0 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_N PF00732.19 CRK20500.1 - 3.4e-14 52.9 0.3 5.8e-12 45.6 0.0 2.5 3 0 0 3 3 3 2 GMC oxidoreductase FAD_binding_2 PF00890.24 CRK20500.1 - 2.6e-05 23.5 0.9 0.00012 21.3 0.5 2.1 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 CRK20500.1 - 0.0037 16.0 0.1 0.0057 15.4 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 CRK20500.1 - 0.0046 17.2 0.3 0.012 15.8 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain CDH-cyt PF16010.5 CRK20500.1 - 0.014 15.1 0.0 0.12 12.0 0.0 2.3 2 0 0 2 2 2 0 Cytochrome domain of cellobiose dehydrogenase Pyr_redox_2 PF07992.14 CRK20500.1 - 0.06 12.6 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CRK20500.1 - 0.11 11.6 1.8 0.13 11.3 0.1 2.0 2 1 0 2 2 2 0 Lycopene cyclase protein Peptidase_M1 PF01433.20 CRK20532.1 - 6.2e-48 163.2 5.7 8.6e-48 162.8 5.7 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 CRK20532.1 - 2.3e-28 99.6 0.2 3.1e-28 99.2 0.2 1.2 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain DUF45 PF01863.17 CRK20532.1 - 0.15 12.1 0.4 0.27 11.2 0.3 1.5 1 1 0 1 1 1 0 Protein of unknown function DUF45 Sec62 PF03839.16 CRK20595.1 - 1.2e-64 217.8 1.6 1.3e-64 217.6 1.6 1.0 1 0 0 1 1 1 1 Translocation protein Sec62 OST3_OST6 PF04756.13 CRK20595.1 - 0.14 11.5 2.7 0.19 11.0 2.7 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Corona_M PF01635.18 CRK20595.1 - 5.5 6.2 9.6 7.5 5.8 9.6 1.2 1 0 0 1 1 1 0 Coronavirus M matrix/glycoprotein adh_short_C2 PF13561.6 CRK20614.1 - 1.7e-24 86.7 0.3 1.5e-22 80.3 0.3 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRK20614.1 - 2.2e-19 69.7 0.1 4.1e-17 62.3 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase DAHP_synth_2 PF01474.16 CRK20617.1 - 2.2e-173 576.8 0.0 5.2e-129 430.6 0.0 2.0 1 1 1 2 2 2 2 Class-II DAHP synthetase family Filo_glycop PF01611.16 CRK20618.1 - 0.14 11.1 0.1 1.4 7.8 0.0 2.0 2 0 0 2 2 2 0 Filovirus glycoprotein PLA2_B PF01735.18 CRK20619.1 - 5e-187 622.2 0.0 5.9e-187 622.0 0.0 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain RANK_CRD_2 PF18278.1 CRK20619.1 - 0.35 11.1 1.6 0.82 9.9 1.6 1.6 1 0 0 1 1 1 0 Receptor activator of the NF-KB cysteine-rich repeat domain 2 WLM PF08325.10 CRK20620.1 - 3.9e-60 203.2 0.2 6.3e-60 202.5 0.2 1.3 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.18 CRK20620.1 - 5.1e-05 22.5 0.6 5.1e-05 22.5 0.6 3.4 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others DZR PF12773.7 CRK20620.1 - 0.027 14.5 4.9 1.4 9.0 0.4 2.4 2 0 0 2 2 2 0 Double zinc ribbon C1_2 PF03107.16 CRK20620.1 - 0.076 13.3 2.9 3.7 8.0 0.5 2.5 2 0 0 2 2 2 0 C1 domain zf-Sec23_Sec24 PF04810.15 CRK20620.1 - 0.3 11.2 10.0 0.19 11.8 0.5 3.1 2 1 1 3 3 3 0 Sec23/Sec24 zinc finger HATPase_c PF02518.26 CRK20622.1 - 4.3e-56 188.2 0.6 6.7e-31 107.1 0.3 2.5 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 CRK20622.1 - 2.8e-47 158.6 1.2 4.2e-22 77.9 0.1 3.3 2 0 0 2 2 2 2 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 CRK20622.1 - 3.7e-29 100.8 0.3 1.2e-15 57.6 0.1 3.1 2 0 0 2 2 2 2 PAS fold Response_reg PF00072.24 CRK20622.1 - 3.9e-22 78.6 0.2 1.2e-21 77.0 0.2 1.9 1 0 0 1 1 1 1 Response regulator receiver domain PAS_4 PF08448.10 CRK20622.1 - 2.2e-10 40.7 6.8 0.0019 18.4 0.0 7.4 7 3 0 7 7 7 2 PAS fold PAS_9 PF13426.7 CRK20622.1 - 5.5e-10 39.4 0.0 0.026 14.8 0.0 5.8 5 0 0 5 5 5 2 PAS domain PAS_8 PF13188.7 CRK20622.1 - 1.9e-09 37.3 4.2 0.076 13.1 0.0 5.4 6 0 0 6 6 6 2 PAS domain PAS PF00989.25 CRK20622.1 - 3.2e-09 36.8 0.0 1.1 9.3 0.0 5.8 7 0 0 7 7 5 3 PAS fold HATPase_c_3 PF13589.6 CRK20622.1 - 9e-08 32.0 0.0 0.02 14.7 0.0 2.5 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GRIP PF01465.20 CRK20622.1 - 0.00077 19.3 1.5 2.5 8.1 0.0 3.6 4 0 0 4 4 4 2 GRIP domain LPD29 PF18847.1 CRK20622.1 - 0.0034 18.3 0.3 6.8 7.7 0.0 2.7 2 0 0 2 2 2 2 Large polyvalent protein associated domain 29 MLTR_LBD PF17765.1 CRK20622.1 - 0.0075 16.4 1.5 5.5 7.1 0.1 3.0 3 0 0 3 3 2 2 MmyB-like transcription regulator ligand binding domain DUF4172 PF13776.6 CRK20622.1 - 0.022 15.1 3.5 6.5 7.2 0.3 3.2 3 0 0 3 3 2 0 Domain of unknown function (DUF4172) DUF2985 PF11204.8 CRK20622.1 - 0.12 12.6 0.1 29 4.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2985) DUF4575 PF15143.6 CRK20622.1 - 0.15 12.3 11.7 2.2 8.5 2.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4575) DUF2997 PF11211.8 CRK20622.1 - 0.17 11.7 2.4 18 5.2 0.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2997) LPP PF04728.13 CRK20622.1 - 0.22 11.9 12.7 3.3 8.2 2.6 2.7 2 0 0 2 2 2 0 Lipoprotein leucine-zipper STAT_int PF02865.17 CRK20622.1 - 3.2 8.2 6.5 26 5.3 0.7 2.5 2 0 0 2 2 2 0 STAT protein, protein interaction domain NAD_binding_6 PF08030.12 CRK20623.1 - 1.1e-22 80.9 0.0 1.7e-22 80.2 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 CRK20623.1 - 2.3e-22 79.1 0.0 4.6e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 CRK20623.1 - 1.5e-19 70.4 13.8 1.6e-19 70.3 9.9 2.2 1 1 1 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 CRK20623.1 - 0.17 12.6 0.0 3.7 8.2 0.0 2.2 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain Myosin_head PF00063.21 CRK20624.1 - 1.2e-236 787.2 5.6 1.4e-236 786.9 5.6 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 CRK20624.1 - 5.9e-49 166.3 0.0 1.2e-48 165.3 0.0 1.6 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_1 PF00018.28 CRK20624.1 - 1.3e-14 53.5 0.6 2.6e-14 52.5 0.6 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CRK20624.1 - 1.7e-12 47.0 0.1 4e-12 45.8 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CRK20624.1 - 1.4e-10 40.7 0.1 3.1e-10 39.6 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain F-box-like PF12937.7 CRK20624.1 - 5.6e-09 35.8 0.3 5.6e-09 35.8 0.3 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CRK20624.1 - 7.7e-05 22.5 0.4 0.00021 21.1 0.4 1.8 1 0 0 1 1 1 1 F-box domain IQ PF00612.27 CRK20624.1 - 0.012 15.4 10.0 0.27 11.1 2.4 2.8 1 1 1 2 2 2 0 IQ calmodulin-binding motif GCFC PF07842.12 CRK20624.1 - 0.015 14.9 0.1 0.03 13.9 0.1 1.4 1 0 0 1 1 1 0 GC-rich sequence DNA-binding factor-like protein Hpr_kinase_C PF07475.12 CRK20624.1 - 0.031 13.8 0.3 8.5 5.9 0.1 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_16 PF13191.6 CRK20624.1 - 0.046 14.1 0.8 0.28 11.5 0.0 2.6 3 0 0 3 3 2 0 AAA ATPase domain AAA_22 PF13401.6 CRK20624.1 - 0.086 13.1 0.0 0.27 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain DHHC PF01529.20 CRK20625.1 - 3.2e-32 111.4 2.4 3.2e-32 111.4 2.4 1.5 2 0 0 2 2 2 1 DHHC palmitoyltransferase Glyco_transf_90 PF05686.12 CRK20626.1 - 1.4e-08 34.1 0.0 0.0024 16.8 0.0 3.3 2 1 0 2 2 2 2 Glycosyl transferase family 90 Aldose_epim PF01263.20 CRK20627.1 - 4e-26 92.0 0.0 5.5e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Rif1_N PF12231.8 CRK20628.1 - 3e-81 273.3 1.4 3.6e-81 273.0 1.4 1.1 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal Peptidase_M24_C PF16188.5 CRK20628.1 - 0.084 12.9 0.4 1.2 9.3 0.1 2.8 3 0 0 3 3 3 0 C-terminal region of peptidase_M24 Aldose_epim PF01263.20 CRK20629.1 - 5.1e-18 65.4 0.0 5.5e-18 65.3 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Glyco_hydro_36N PF16875.5 CRK20629.1 - 0.0061 16.1 0.0 0.0091 15.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 N-terminal domain Rif1_N PF12231.8 CRK20630.1 - 3.9e-129 430.9 0.4 1.3e-128 429.2 0.1 1.9 2 0 0 2 2 2 1 Rap1-interacting factor 1 N terminal Ric8 PF10165.9 CRK20631.1 - 3.3e-81 273.7 1.3 3.6e-73 247.2 0.0 3.0 3 1 1 4 4 4 2 Guanine nucleotide exchange factor synembryn PQ-loop PF04193.14 CRK20631.1 - 1.2e-21 76.2 1.9 6.9e-11 41.8 0.2 2.3 2 0 0 2 2 2 2 PQ loop repeat Ric8 PF10165.9 CRK20633.1 - 9.8e-119 397.4 0.0 1.5e-118 396.8 0.0 1.3 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Chromo PF00385.24 CRK20635.1 - 1.6e-15 56.8 0.2 2.6e-15 56.0 0.2 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AT_hook PF02178.19 CRK20635.1 - 0.0015 18.1 24.8 0.16 11.9 3.3 4.4 3 0 0 3 3 3 3 AT hook motif PQ-loop PF04193.14 CRK20637.1 - 5.4e-23 80.5 1.9 1.5e-11 43.9 0.2 2.4 2 0 0 2 2 2 2 PQ loop repeat NUDIX PF00293.28 CRK20640.1 - 1.9e-16 60.3 1.2 2.3e-16 60.0 1.2 1.1 1 0 0 1 1 1 1 NUDIX domain DUF4691 PF15762.5 CRK20640.1 - 0.034 14.3 0.1 0.073 13.2 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4691) LSM PF01423.22 CRK20642.1 - 9.3e-15 54.1 0.0 1.4e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 LSM domain Arm-DNA-bind_3 PF13356.6 CRK20642.1 - 0.031 14.7 0.0 0.056 13.8 0.0 1.4 1 0 0 1 1 1 0 Arm DNA-binding domain Glyco_hyd_65N_2 PF14498.6 CRK20644.1 - 0.013 15.4 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Mob1_phocein PF03637.17 CRK20646.1 - 3.2e-69 232.3 0.0 4.1e-69 231.9 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family OSCP PF00213.18 CRK20648.1 - 1e-47 162.5 2.5 1.3e-47 162.2 2.5 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit DUF1993 PF09351.10 CRK20648.1 - 0.05 13.8 0.5 0.11 12.7 0.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1993) Glyco_hydro_63 PF03200.16 CRK20650.1 - 2.8e-07 29.7 9.6 2.4e-06 26.6 0.1 4.1 5 1 0 5 5 5 2 Glycosyl hydrolase family 63 C-terminal domain TTSSLRR PF12468.8 CRK20650.1 - 0.11 12.7 0.1 0.31 11.3 0.1 1.7 1 0 0 1 1 1 0 Type III secretion system leucine rich repeat protein NmrA PF05368.13 CRK20675.1 - 1.9e-05 24.4 0.0 2.2e-05 24.1 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family DUF1729 PF08354.10 CRK20752.1 - 4.3e-43 147.6 0.0 5.4e-43 147.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) FAS_meander PF17951.1 CRK20752.1 - 2e-23 82.8 0.0 4.2e-23 81.8 0.0 1.5 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain Amidohydro_1 PF01979.20 CRK20752.1 - 9.2e-06 25.2 0.1 1.4e-05 24.6 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase family DUF3287 PF11690.8 CRK20753.1 - 0.02 14.6 1.6 0.02 14.6 1.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3287) Seryl_tRNA_N PF02403.22 CRK20753.1 - 0.11 12.8 16.2 0.15 12.3 16.2 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF3584 PF12128.8 CRK20753.1 - 0.21 9.1 15.7 0.23 8.9 15.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4407 PF14362.6 CRK20753.1 - 0.35 10.2 16.0 0.41 10.0 16.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) COMPASS-Shg1 PF05205.12 CRK20753.1 - 0.47 11.2 10.9 1.8 9.3 3.1 2.1 1 1 1 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 Prefoldin_2 PF01920.20 CRK20753.1 - 0.49 10.4 18.3 17 5.4 18.3 2.5 1 1 0 1 1 1 0 Prefoldin subunit DUF5082 PF16888.5 CRK20753.1 - 0.58 10.5 12.4 1 9.6 11.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) Ax_dynein_light PF10211.9 CRK20753.1 - 1.6 8.7 16.2 0.83 9.6 13.0 1.8 1 1 1 2 2 2 0 Axonemal dynein light chain FUSC PF04632.12 CRK20753.1 - 1.9 6.9 6.0 2 6.9 6.0 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF724 PF05266.14 CRK20753.1 - 2.5 7.9 16.2 0.64 9.8 11.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Vfa1 PF08432.10 CRK20753.1 - 4.7 7.5 16.7 5.2 7.4 16.7 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Jnk-SapK_ap_N PF09744.9 CRK20753.1 - 6.6 6.9 17.0 11 6.2 17.0 1.4 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF1348 PF07080.11 CRK20756.1 - 3.6e-64 214.5 7.9 4.3e-64 214.3 7.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.7 CRK20756.1 - 2.5e-07 31.3 0.4 3.3e-07 30.9 0.4 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 CRK20756.1 - 2.2e-05 24.8 0.0 3.3e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) Redoxin PF08534.10 CRK20758.1 - 3.4e-38 130.7 0.0 3.7e-38 130.5 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 CRK20758.1 - 3e-07 30.4 0.0 3.9e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Ribosomal_L24e PF01246.20 CRK20760.1 - 1.4e-29 102.1 0.2 3.4e-29 100.9 0.2 1.7 1 0 0 1 1 1 1 Ribosomal protein L24e SSB PF00436.25 CRK20760.1 - 0.33 11.0 3.3 1.5 8.9 2.4 2.0 2 0 0 2 2 2 0 Single-strand binding protein family CBP4 PF07960.11 CRK20761.1 - 1.2e-27 96.3 1.0 1.5e-27 96.0 1.0 1.0 1 0 0 1 1 1 1 CBP4 Trp_oprn_chp PF09534.10 CRK20761.1 - 0.12 12.1 0.0 0.2 11.5 0.0 1.3 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF2852 PF11014.8 CRK20761.1 - 0.27 11.4 2.6 0.54 10.4 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) Sel1 PF08238.12 CRK20763.1 - 3e-41 138.9 26.9 5.4e-08 33.3 0.0 8.0 8 0 0 8 8 8 7 Sel1 repeat TPR_17 PF13431.6 CRK20763.1 - 0.0075 16.6 1.2 0.69 10.4 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.6 CRK20763.1 - 0.099 13.0 0.4 1.2 9.5 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 CRK20763.1 - 2.1 9.4 12.7 0.98 10.4 0.1 5.1 4 1 1 5 5 5 0 Tetratricopeptide repeat MPC PF03650.13 CRK20765.1 - 2.7e-46 156.3 0.3 3.6e-46 155.8 0.3 1.2 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers MtN3_slv PF03083.16 CRK20765.1 - 0.15 12.2 0.6 0.25 11.4 0.6 1.5 1 1 0 1 1 1 0 Sugar efflux transporter for intercellular exchange L51_S25_CI-B8 PF05047.16 CRK20767.1 - 1.2e-13 50.8 0.0 1.5e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain CaM_binding PF07839.11 CRK20767.1 - 0.039 14.7 0.0 0.045 14.5 0.0 1.1 1 0 0 1 1 1 0 Plant calmodulin-binding domain DUF1687 PF07955.11 CRK20771.1 - 1.8e-34 119.0 0.2 2.3e-34 118.6 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) Ribosomal_L14e PF01929.17 CRK20774.1 - 1.6e-29 102.2 4.1 2e-29 101.9 4.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 CRK20774.1 - 0.0012 18.7 0.3 0.0027 17.6 0.0 1.7 2 0 0 2 2 2 1 KOW motif NAC PF01849.18 CRK20776.1 - 5.6e-23 80.7 0.1 2.9e-22 78.4 0.0 2.1 2 0 0 2 2 2 1 NAC domain Med7 PF05983.11 CRK20776.1 - 0.0062 16.6 1.1 0.012 15.7 1.1 1.6 1 1 0 1 1 1 1 MED7 protein Myc_N PF01056.18 CRK20776.1 - 0.0089 16.0 6.6 0.0089 16.0 6.6 1.9 1 1 1 2 2 2 1 Myc amino-terminal region CSRNP_N PF16019.5 CRK20776.1 - 8.3 6.3 7.2 3.2 7.6 0.4 2.1 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus Abhydrolase_3 PF07859.13 CRK20778.1 - 5.3e-68 229.0 0.0 4.5e-33 114.9 0.0 2.6 2 0 0 2 2 2 2 alpha/beta hydrolase fold Mt_ATP-synt_D PF05873.12 CRK20778.1 - 6.8e-33 113.7 14.7 3e-17 62.9 2.0 2.7 2 1 1 3 3 3 2 ATP synthase D chain, mitochondrial (ATP5H) NAC PF01849.18 CRK20778.1 - 8.3e-22 76.9 0.2 2.4e-21 75.5 0.0 2.0 2 0 0 2 2 1 1 NAC domain Abhydrolase_6 PF12697.7 CRK20778.1 - 2.5e-05 25.0 2.7 0.24 12.0 0.1 3.1 2 1 1 3 3 3 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CRK20778.1 - 0.00015 21.1 0.0 0.83 8.9 0.0 2.9 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Meth_synt_1 PF08267.12 CRK20778.1 - 0.003 17.1 0.1 2 7.9 0.0 2.3 2 0 0 2 2 2 2 Cobalamin-independent synthase, N-terminal domain Abhydrolase_5 PF12695.7 CRK20778.1 - 0.0035 17.1 0.0 2.6 7.8 0.0 2.5 2 0 0 2 2 2 2 Alpha/beta hydrolase family T5orf172 PF10544.9 CRK20778.1 - 0.011 16.3 0.3 9.1 6.9 0.0 2.6 2 0 0 2 2 2 0 T5orf172 domain Peptidase_S9 PF00326.21 CRK20778.1 - 0.012 15.1 0.0 2.6 7.5 0.0 2.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family HGAL PF15666.5 CRK20778.1 - 0.017 15.2 0.0 17 5.6 0.0 3.2 2 0 0 2 2 2 0 Germinal center-associated lymphoma Lipase_3 PF01764.25 CRK20778.1 - 0.023 14.6 0.0 11 5.9 0.0 2.6 2 0 0 2 2 2 0 Lipase (class 3) COesterase PF00135.28 CRK20778.1 - 0.085 11.7 0.3 6.1 5.6 0.0 2.5 2 0 0 2 2 2 0 Carboxylesterase family Cas6b_N PF17955.1 CRK20778.1 - 0.11 12.6 0.0 38 4.4 0.0 3.1 3 0 0 3 3 3 0 Cas6b N-terminal domain DUF4376 PF14301.6 CRK20778.1 - 0.26 11.7 3.6 16 5.9 0.5 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4376) Myc_N PF01056.18 CRK20778.1 - 0.3 11.0 10.5 0.69 9.7 10.1 1.7 1 1 0 1 1 1 0 Myc amino-terminal region MbeB_N PF04837.12 CRK20778.1 - 2.8 8.3 5.9 32 4.9 0.6 2.7 2 0 0 2 2 2 0 MbeB-like, N-term conserved region DUF501 PF04417.12 CRK20778.1 - 3 7.7 5.7 18 5.1 0.0 3.3 4 0 0 4 4 3 0 Protein of unknown function (DUF501) Glyco_hydro_31 PF01055.26 CRK20789.1 - 2.3e-112 376.4 1.3 3.4e-112 375.8 1.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 CRK20789.1 - 0.00048 20.4 0.2 0.0034 17.7 0.2 2.4 1 1 0 1 1 1 1 Galactose mutarotase-like DUF4968 PF16338.5 CRK20789.1 - 0.0055 17.0 0.0 0.0091 16.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4968) Sugar_tr PF00083.24 CRK20791.1 - 1.5e-80 271.3 28.1 1.8e-80 271.0 28.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK20791.1 - 1e-16 60.8 45.9 1.9e-11 43.5 30.3 2.5 1 1 2 3 3 3 3 Major Facilitator Superfamily FixS PF03597.15 CRK20791.1 - 3.7 7.4 0.0 3.7 7.4 0.0 3.4 4 1 1 5 5 5 0 Cytochrome oxidase maturation protein cbb3-type LANC_like PF05147.13 CRK20793.1 - 9.5e-24 83.6 0.0 6.6e-22 77.6 0.0 2.1 2 0 0 2 2 2 2 Lanthionine synthetase C-like protein zf-RING_2 PF13639.6 CRK20795.1 - 1.1e-12 48.0 5.3 2e-12 47.2 5.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CRK20795.1 - 3e-10 39.8 4.5 5.9e-10 38.8 4.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CRK20795.1 - 2.7e-09 37.2 2.7 5.4e-09 36.2 2.7 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CRK20795.1 - 1e-08 34.9 3.9 1.8e-08 34.1 3.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CRK20795.1 - 1.1e-08 34.7 2.5 1.1e-08 34.7 2.5 1.9 2 0 0 2 2 2 1 RING-like zinc finger PA PF02225.22 CRK20795.1 - 1.2e-08 34.9 0.0 2.6e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 PA domain zf-RING_5 PF14634.6 CRK20795.1 - 4e-07 29.9 3.0 7.8e-07 29.0 3.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CRK20795.1 - 9.5e-07 28.7 3.5 2.7e-06 27.3 0.4 2.9 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CRK20795.1 - 5.2e-06 26.2 2.9 8.6e-06 25.5 2.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CRK20795.1 - 0.0013 18.7 1.0 0.0026 17.8 1.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 CRK20795.1 - 0.0032 17.3 3.1 0.0084 15.9 3.1 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 CRK20795.1 - 0.025 14.2 3.1 0.05 13.2 3.1 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 CRK20795.1 - 0.088 13.0 5.7 0.1 12.8 3.5 2.3 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 CRK20795.1 - 0.096 12.9 2.7 0.25 11.6 2.7 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 CRK20795.1 - 0.11 12.3 3.0 0.24 11.2 3.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.29 CRK20795.1 - 0.16 11.9 3.0 0.28 11.1 3.0 1.4 1 0 0 1 1 1 0 PHD-finger RINGv PF12906.7 CRK20795.1 - 0.23 11.6 4.2 0.46 10.6 4.2 1.5 1 0 0 1 1 1 0 RING-variant domain zf-Nse PF11789.8 CRK20795.1 - 0.48 10.3 2.8 1 9.2 2.8 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING-like PF08746.11 CRK20795.1 - 0.75 10.1 3.5 1.4 9.3 3.5 1.5 1 0 0 1 1 1 0 RING-like domain DUF4083 PF13314.6 CRK20795.1 - 0.91 9.5 3.8 12 5.9 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) Spc7 PF08317.11 CRK20798.1 - 0.00012 21.1 15.7 0.0068 15.3 1.3 3.0 3 0 0 3 3 3 2 Spc7 kinetochore protein BLOC1_2 PF10046.9 CRK20798.1 - 0.0089 16.3 2.3 0.0089 16.3 2.3 2.7 3 0 0 3 3 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Baculo_PEP_C PF04513.12 CRK20798.1 - 0.053 13.6 0.8 0.35 10.9 0.1 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prefoldin PF02996.17 CRK20798.1 - 0.053 13.4 4.0 0.17 11.8 0.2 3.0 1 1 2 3 3 3 0 Prefoldin subunit Atg14 PF10186.9 CRK20798.1 - 0.14 11.2 17.6 0.035 13.2 1.7 2.3 1 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1664 PF07889.12 CRK20798.1 - 0.16 12.0 5.0 3.1 7.8 0.4 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) LMBR1 PF04791.16 CRK20798.1 - 0.45 9.4 3.4 0.53 9.1 3.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein PAXX PF15384.6 CRK20798.1 - 0.49 10.1 7.3 0.38 10.4 0.5 2.5 1 1 0 2 2 2 0 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 Laminin_II PF06009.12 CRK20798.1 - 0.68 10.0 12.2 2.2 8.3 1.6 3.3 2 1 1 3 3 3 0 Laminin Domain II DHR10 PF18595.1 CRK20798.1 - 0.72 9.9 20.9 0.56 10.3 15.5 3.3 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain DUF4407 PF14362.6 CRK20798.1 - 0.79 9.0 13.9 2.6 7.3 13.7 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) FapA PF03961.13 CRK20798.1 - 1.5 7.4 8.8 7.9 5.0 9.1 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A DUF2205 PF10224.9 CRK20798.1 - 2.2 8.4 11.1 3.3 7.8 1.7 2.7 2 0 0 2 2 2 0 Short coiled-coil protein ABC_tran_CTD PF16326.5 CRK20798.1 - 2.3 8.6 25.4 0.13 12.5 4.5 4.2 2 1 2 4 4 4 0 ABC transporter C-terminal domain DUF2730 PF10805.8 CRK20798.1 - 2.5 8.3 8.5 5.8 7.1 0.4 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) Spc24 PF08286.11 CRK20798.1 - 4 7.7 13.7 0.7 10.2 1.8 3.2 3 1 0 3 3 3 0 Spc24 subunit of Ndc80 UPF0242 PF06785.11 CRK20798.1 - 4.8 7.2 19.3 2.2 8.3 9.7 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus FlaC_arch PF05377.11 CRK20798.1 - 5.5 7.5 6.6 26 5.3 0.8 3.6 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) OmpH PF03938.14 CRK20798.1 - 6 7.2 20.8 3.6 7.9 3.0 2.7 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) Fez1 PF06818.15 CRK20798.1 - 6.5 7.2 18.5 8.8 6.7 7.6 2.4 1 1 2 3 3 3 0 Fez1 FlxA PF14282.6 CRK20798.1 - 7 6.7 16.7 3.9 7.5 3.8 3.1 3 1 0 3 3 3 0 FlxA-like protein TolA_bind_tri PF16331.5 CRK20798.1 - 7.2 6.8 16.3 5.2 7.2 2.9 3.9 3 1 1 4 4 4 0 TolA binding protein trimerisation DivIC PF04977.15 CRK20798.1 - 8.5 6.2 20.3 4.1 7.2 5.1 3.9 2 1 1 3 3 3 0 Septum formation initiator IFT20 PF14931.6 CRK20798.1 - 9.4 6.4 14.3 0.2 11.9 4.6 2.6 2 1 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 Ribosomal_L37e PF01907.19 CRK20800.1 - 3e-24 84.9 11.3 4.3e-14 52.4 1.2 2.4 2 0 0 2 2 2 2 Ribosomal protein L37e GFA PF04828.14 CRK20800.1 - 0.035 14.4 0.4 6.6 7.2 0.1 2.3 2 0 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DUF2147 PF09917.9 CRK20800.1 - 0.038 14.7 0.4 0.055 14.1 0.4 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2147) DZR PF12773.7 CRK20800.1 - 0.052 13.6 0.8 0.12 12.4 0.3 1.8 2 1 0 2 2 2 0 Double zinc ribbon DUF4570 PF15134.6 CRK20800.1 - 0.16 12.0 0.0 0.23 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) zinc_ribbon_11 PF11682.8 CRK20800.1 - 0.18 11.8 1.6 1.4 8.9 1.5 2.1 1 1 0 1 1 1 0 Probable zinc-ribbon ELP6 PF09807.9 CRK20802.1 - 1.9e-08 34.0 0.0 4.8e-08 32.7 0.0 1.6 1 1 0 1 1 1 1 Elongation complex protein 6 rhaM PF05336.13 CRK20804.1 - 4.2e-37 126.5 0.7 5.7e-37 126.1 0.7 1.2 1 0 0 1 1 1 1 L-rhamnose mutarotase DOT1 PF08123.13 CRK20804.1 - 0.11 12.0 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Histone methylation protein DOT1 Thioredoxin PF00085.20 CRK20805.1 - 6.5e-06 26.1 0.0 9.4e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 CRK20805.1 - 0.0044 16.4 0.0 0.0053 16.1 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 CRK20805.1 - 0.017 15.3 0.0 0.03 14.5 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like Redoxin PF08534.10 CRK20805.1 - 0.049 13.3 0.0 0.067 12.9 0.0 1.2 1 0 0 1 1 1 0 Redoxin Thioredoxin_9 PF14595.6 CRK20805.1 - 0.14 11.9 0.0 0.34 10.7 0.0 1.5 2 0 0 2 2 2 0 Thioredoxin MFS_1 PF07690.16 CRK20807.1 - 1e-39 136.5 28.2 2.8e-30 105.4 7.0 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK20807.1 - 5.1e-16 58.6 2.7 5.1e-16 58.6 2.7 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 CRK20807.1 - 0.00012 20.6 3.2 0.0002 19.9 3.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PRT_C PF08372.10 CRK20807.1 - 0.41 10.4 3.5 0.27 11.0 0.7 2.0 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal UPF0016 PF01169.19 CRK20809.1 - 2.6e-40 136.6 24.5 6.1e-20 71.3 9.7 2.3 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Sugar_tr PF00083.24 CRK20812.1 - 1.8e-71 241.3 25.9 2.1e-71 241.1 25.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK20812.1 - 6.5e-13 48.3 33.1 6.5e-13 48.3 33.1 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Phage_holin_2_4 PF16082.5 CRK20812.1 - 1.5 8.6 5.8 5 6.9 0.0 3.4 3 0 0 3 3 3 0 Bacteriophage holin family, superfamily II-like WD40 PF00400.32 CRK20814.1 - 2.4e-21 75.6 18.2 4.5e-05 24.1 0.8 7.5 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK20814.1 - 0.0001 22.5 0.0 0.044 14.1 0.0 3.7 4 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 CRK20814.1 - 0.00015 20.4 4.9 0.0059 15.2 0.2 3.4 4 0 0 4 4 4 2 Cytochrome D1 heme domain SDA1 PF05285.12 CRK20814.1 - 0.015 14.7 14.1 0.021 14.3 14.1 1.2 1 0 0 1 1 1 0 SDA1 PD40 PF07676.12 CRK20814.1 - 0.022 14.7 0.0 0.13 12.2 0.0 2.4 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat SecE PF00584.20 CRK20816.1 - 5.7e-11 42.2 0.0 7.6e-11 41.8 0.0 1.3 1 1 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Zip PF02535.22 CRK20817.1 - 2.8 7.0 4.2 3.2 6.9 4.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.14 CRK20817.1 - 6.4 4.9 10.0 7.5 4.7 10.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Sugar_tr PF00083.24 CRK20818.1 - 5e-31 108.0 15.0 1.4e-30 106.6 15.0 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter DUF3346 PF11826.8 CRK20818.1 - 0.04 13.7 0.1 0.065 13.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3346) Coq4 PF05019.13 CRK20819.1 - 1.7e-94 315.3 0.0 3.2e-94 314.4 0.0 1.5 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 dsDNA_bind PF01984.20 CRK20820.1 - 2.4e-41 140.5 10.7 2.7e-41 140.3 10.7 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain mRNA_triPase PF02940.15 CRK20820.1 - 0.096 12.4 0.5 0.17 11.6 0.2 1.6 2 0 0 2 2 2 0 mRNA capping enzyme, beta chain K_channel_TID PF07941.11 CRK20820.1 - 0.24 11.9 7.0 0.45 11.0 7.0 1.4 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain APH PF01636.23 CRK20821.1 - 1.9e-18 67.3 0.0 2.8e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 CRK20821.1 - 1.7e-06 27.8 0.0 0.0012 18.5 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Choline_kinase PF01633.20 CRK20821.1 - 3.1e-05 23.7 0.0 4.8e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 CRK20821.1 - 0.0058 16.0 0.0 2.1 7.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Kdo PF06293.14 CRK20821.1 - 0.015 14.7 0.0 0.92 8.8 0.0 2.3 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Fructosamin_kin PF03881.14 CRK20821.1 - 0.02 14.1 0.0 0.26 10.5 0.0 2.0 2 0 0 2 2 2 0 Fructosamine kinase HEAT PF02985.22 CRK20822.1 - 0.051 13.8 0.1 0.16 12.3 0.1 1.8 1 0 0 1 1 1 0 HEAT repeat Sugar_tr PF00083.24 CRK20831.1 - 7e-38 130.6 8.0 7.9e-38 130.5 8.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK20831.1 - 3.7e-14 52.4 9.5 4.4e-14 52.2 9.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 CRK20831.1 - 5.9e-05 21.8 0.3 9.2e-05 21.2 0.3 1.2 1 0 0 1 1 1 1 MFS/sugar transport protein SecY PF00344.20 CRK20831.1 - 0.0082 15.4 0.1 0.0082 15.4 0.1 1.4 2 0 0 2 2 2 1 SecY translocase DUF4316 PF14195.6 CRK20831.1 - 0.058 13.1 0.1 0.094 12.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4316) RibD_C PF01872.17 CRK20835.1 - 4.8e-18 65.7 0.0 5.8e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 RibD C-terminal domain NMT1 PF09084.11 CRK20836.1 - 6.8e-26 91.6 0.0 7.5e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like Sporozoite_P67 PF05642.11 CRK20836.1 - 0.057 11.5 1.8 0.05 11.7 1.8 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PBP_like PF12727.7 CRK20836.1 - 0.08 12.1 0.0 0.14 11.3 0.0 1.3 1 1 0 1 1 1 0 PBP superfamily domain STAT1_TAZ2bind PF12162.8 CRK20836.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 STAT1 TAZ2 binding domain Spermine_synth PF01564.17 CRK20840.1 - 1.4e-70 236.5 0.0 3.3e-70 235.3 0.0 1.5 2 0 0 2 2 2 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 CRK20840.1 - 5.5e-25 87.0 0.2 9e-25 86.3 0.2 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 CRK20840.1 - 0.00042 21.0 0.0 0.0012 19.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK20840.1 - 0.0014 18.4 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK20840.1 - 0.0072 17.0 0.4 0.054 14.3 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain DUF43 PF01861.16 CRK20840.1 - 0.017 14.3 0.0 0.028 13.6 0.0 1.3 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain G-alpha PF00503.20 CRK20841.1 - 1.4e-105 353.3 0.1 2e-105 352.9 0.1 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Glyco_hydro_3_C PF01915.22 CRK20841.1 - 1.8e-40 139.1 0.0 4.3e-40 137.9 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 CRK20841.1 - 9.2e-37 127.1 0.0 1.6e-36 126.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 CRK20841.1 - 2.5e-21 75.5 0.0 4.8e-21 74.6 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Arf PF00025.21 CRK20841.1 - 3.8e-12 46.0 0.1 1.8e-07 30.8 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CRK20841.1 - 0.0053 16.1 0.3 0.21 10.9 0.0 2.2 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region FtsK_SpoIIIE PF01580.18 CRK20841.1 - 0.095 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family GATA PF00320.27 CRK20844.1 - 5.4e-16 57.9 3.5 8.4e-16 57.3 3.5 1.3 1 0 0 1 1 1 1 GATA zinc finger GCS PF03074.16 CRK20848.1 - 5.5e-174 578.7 0.0 6.8e-174 578.4 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase CN_hydrolase PF00795.22 CRK20848.1 - 2.1e-54 184.6 0.0 3.1e-54 184.1 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase GCS2 PF04107.13 CRK20848.1 - 0.029 13.7 0.0 4.3 6.6 0.0 2.4 2 0 0 2 2 2 0 Glutamate-cysteine ligase family 2(GCS2) Ran_BP1 PF00638.18 CRK20850.1 - 1.5e-12 47.8 0.0 4.5e-12 46.3 0.0 1.7 1 1 0 1 1 1 1 RanBP1 domain SCP2 PF02036.17 CRK20850.1 - 8.4e-08 32.6 0.0 1.6e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 SCP-2 sterol transfer family Nucleoporin_FG PF13634.6 CRK20850.1 - 0.00091 20.0 45.8 0.0018 19.1 7.9 10.9 2 1 8 11 11 11 4 Nucleoporin FG repeat region RCR PF12273.8 CRK20851.1 - 0.00014 22.5 0.1 0.0005 20.7 0.1 1.9 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red TMEM154 PF15102.6 CRK20851.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family Tfb5 PF06331.12 CRK20853.1 - 1.1e-26 92.6 0.8 1.2e-26 92.4 0.8 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 ECH_1 PF00378.20 CRK20855.1 - 1.9e-38 132.2 0.2 4.7e-38 130.9 0.2 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CRK20855.1 - 5.8e-33 114.8 0.0 5e-29 101.8 0.0 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase PEP_hydrolase PF09370.10 CRK20855.1 - 0.02 14.1 0.3 0.034 13.4 0.3 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate hydrolase-like DUF2188 PF09954.9 CRK20855.1 - 0.15 12.3 0.1 0.28 11.3 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2188) MFS_1 PF07690.16 CRK20857.1 - 9.1e-06 24.8 16.5 0.002 17.2 13.8 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_72 PF03198.14 CRK20859.1 - 7.5e-121 403.2 5.2 9.8e-121 402.8 5.2 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 CRK20859.1 - 1.2e-06 28.2 0.7 7.8e-06 25.5 0.7 1.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 CRK20859.1 - 0.0006 19.0 0.1 0.00079 18.6 0.1 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Herpes_pp85 PF04637.12 CRK20859.1 - 0.033 12.6 0.0 0.054 11.9 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) FCH PF00611.23 CRK20861.1 - 2e-26 92.1 1.5 3.7e-26 91.2 0.1 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.6 CRK20861.1 - 2e-22 78.8 0.6 2.5e-12 46.4 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain C1_1 PF00130.22 CRK20861.1 - 1.4e-14 53.7 4.8 2.2e-14 53.0 4.8 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_1 PF00018.28 CRK20861.1 - 1.3e-13 50.3 0.1 1.8e-06 27.4 0.0 2.4 2 0 0 2 2 2 2 SH3 domain SH3_3 PF08239.11 CRK20861.1 - 0.00088 19.5 0.3 0.14 12.5 0.1 2.7 2 0 0 2 2 2 1 Bacterial SH3 domain SH3_2 PF07653.17 CRK20861.1 - 0.0047 16.6 0.2 3.2 7.5 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain C1_2 PF03107.16 CRK20861.1 - 0.0079 16.5 4.3 0.014 15.7 4.3 1.4 1 0 0 1 1 1 1 C1 domain SH3_10 PF17902.1 CRK20861.1 - 0.061 13.4 0.0 15 5.8 0.0 3.1 2 0 0 2 2 2 0 SH3 domain Allexi_40kDa PF05549.11 CRK20861.1 - 0.097 12.2 0.6 1.3 8.4 0.0 2.4 2 0 0 2 2 2 0 Allexivirus 40kDa protein FYVE PF01363.21 CRK20861.1 - 0.26 11.4 3.2 0.53 10.5 3.2 1.4 1 0 0 1 1 1 0 FYVE zinc finger DUF4337 PF14235.6 CRK20861.1 - 0.59 10.2 4.6 2 8.5 4.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF2362 PF10154.9 CRK20861.1 - 0.87 8.5 7.1 1.3 7.8 7.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) Podoplanin PF05808.11 CRK20864.1 - 0.00013 22.2 4.6 0.00013 22.2 4.6 2.3 3 0 0 3 3 3 1 Podoplanin CFEM PF05730.11 CRK20864.1 - 0.049 13.7 5.7 0.092 12.9 5.7 1.5 1 0 0 1 1 1 0 CFEM domain Uds1 PF15456.6 CRK20865.1 - 3.4e-17 62.8 1.9 3.4e-17 62.8 1.9 2.7 2 1 1 3 3 3 1 Up-regulated During Septation DUF3446 PF11928.8 CRK20865.1 - 0.024 14.9 0.4 0.024 14.9 0.4 3.5 2 1 0 2 2 2 0 Early growth response N-terminal domain 4F5 PF04419.14 CRK20874.1 - 1.1e-09 39.0 5.8 1.1e-09 39.0 5.8 1.0 1 0 0 1 1 1 1 4F5 protein family DUF1939 PF09154.10 CRK20886.1 - 0.055 13.6 0.1 0.089 13.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1939) HSBP1 PF06825.12 CRK20889.1 - 0.0016 18.3 0.4 0.0031 17.3 0.4 1.5 1 0 0 1 1 1 1 Heat shock factor binding protein 1 IMD PF08397.11 CRK20889.1 - 0.006 16.0 2.5 0.0073 15.7 2.5 1.3 1 0 0 1 1 1 1 IRSp53/MIM homology domain Glyco_hydro_16 PF00722.21 CRK20893.1 - 1.5e-13 50.6 0.0 1.7e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 U3snoRNP10 PF12397.8 CRK20894.1 - 2e-22 79.7 0.0 3.9e-22 78.8 0.0 1.5 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 10 Glyco_hydro_61 PF03443.14 CRK20901.1 - 6.2e-51 173.3 0.0 8.6e-51 172.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 EHN PF06441.12 CRK20901.1 - 5.8e-37 126.4 0.3 2.5e-35 121.1 0.0 2.4 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 CRK20901.1 - 1.3e-11 44.6 0.1 2.4e-11 43.8 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CRK20901.1 - 0.00057 20.5 2.2 0.00057 20.5 2.2 2.8 3 1 0 3 3 3 1 Alpha/beta hydrolase family Glyco_hydro_12 PF01670.16 CRK20902.1 - 4.8e-52 177.1 2.0 5.4e-52 176.9 2.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 MFS_1 PF07690.16 CRK20903.1 - 4.8e-20 71.8 11.9 6.4e-20 71.4 11.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF859 PF05895.12 CRK20904.1 - 0.028 12.9 0.1 0.052 12.1 0.1 1.4 1 0 0 1 1 1 0 Siphovirus protein of unknown function (DUF859) ThylakoidFormat PF11264.8 CRK20904.1 - 0.2 11.3 0.0 0.29 10.8 0.0 1.2 1 0 0 1 1 1 0 Thylakoid formation protein DUF4419 PF14388.6 CRK20906.1 - 1.8e-96 323.2 0.0 2.5e-96 322.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) NAD_binding_9 PF13454.6 CRK20906.1 - 0.00013 22.0 0.0 0.002 18.1 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding FMO-like PF00743.19 CRK20906.1 - 0.00032 19.3 0.0 0.056 11.9 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 CRK20906.1 - 0.0013 18.0 0.1 0.75 8.9 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 CRK20906.1 - 0.0016 18.7 0.0 0.0034 17.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CRK20906.1 - 0.22 10.7 0.0 0.4 9.9 0.0 1.3 1 0 0 1 1 1 0 Thi4 family ABC_tran PF00005.27 CRK20907.1 - 1.7e-39 135.5 0.0 1.2e-18 67.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 CRK20907.1 - 6.1e-22 78.6 35.9 3e-21 76.3 17.5 3.2 3 1 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 CRK20907.1 - 3.4e-08 33.2 0.3 0.0032 16.9 0.0 4.3 3 1 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CRK20907.1 - 1.3e-07 31.3 0.0 0.02 14.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 CRK20907.1 - 2.6e-07 30.7 0.2 0.035 14.2 0.0 3.7 4 0 0 4 4 4 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CRK20907.1 - 1.8e-06 28.0 0.1 0.079 12.9 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 CRK20907.1 - 7.2e-06 26.0 2.1 1.7 8.4 0.0 3.7 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 CRK20907.1 - 8.8e-05 22.8 0.0 0.37 11.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CRK20907.1 - 0.00012 22.5 0.0 0.51 10.7 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 CRK20907.1 - 0.00046 20.8 0.0 0.04 14.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 CRK20907.1 - 0.0013 18.8 0.6 0.063 13.3 0.0 2.4 2 0 0 2 2 2 1 Dynamin family T2SSE PF00437.20 CRK20907.1 - 0.0014 17.8 0.0 0.021 13.9 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_7 PF12775.7 CRK20907.1 - 0.0016 18.0 0.0 0.5 9.9 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_15 PF13175.6 CRK20907.1 - 0.0018 18.1 0.0 0.3 10.7 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 CRK20907.1 - 0.0097 16.5 0.0 5 7.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CRK20907.1 - 0.01 16.0 0.0 2.3 8.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 CRK20907.1 - 0.018 14.6 0.1 6.8 6.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 CRK20907.1 - 0.12 12.0 0.0 0.38 10.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CRK20907.1 - 0.14 12.6 0.0 15 6.1 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Roc PF08477.13 CRK20907.1 - 0.14 12.4 0.1 13 6.0 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 CRK20907.1 - 0.15 11.4 0.1 15 4.8 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family Tocopherol_cycl PF14249.6 CRK20907.1 - 0.16 11.0 0.1 0.28 10.3 0.1 1.2 1 0 0 1 1 1 0 Tocopherol cyclase MFS_1 PF07690.16 CRK20908.1 - 1.5e-14 53.7 34.5 2.4e-12 46.5 33.4 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3429 PF11911.8 CRK20908.1 - 0.061 13.6 0.4 0.061 13.6 0.4 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF3429) DUF2148 PF09918.9 CRK20908.1 - 0.15 12.1 0.6 16 5.6 0.1 3.0 2 0 0 2 2 2 0 Uncharacterized protein containing a ferredoxin domain (DUF2148) Sugar_tr PF00083.24 CRK20908.1 - 0.27 10.0 20.0 0.013 14.4 7.4 3.1 3 0 0 3 3 3 0 Sugar (and other) transporter DUF4131 PF13567.6 CRK20908.1 - 0.37 10.4 4.0 7.5 6.2 0.7 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) HlyIII PF03006.20 CRK20908.1 - 0.38 10.4 5.6 0.26 11.0 0.4 2.6 1 1 1 2 2 2 0 Haemolysin-III related Methyltransf_2 PF00891.18 CRK20909.1 - 3e-23 82.2 0.0 4.8e-23 81.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_31 PF13847.6 CRK20909.1 - 0.0048 16.7 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK20909.1 - 0.038 14.7 0.0 0.096 13.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.9 CRK20909.1 - 0.045 13.5 0.0 0.079 12.7 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase PAP2 PF01569.21 CRK20910.1 - 2.3e-21 76.0 3.6 2.3e-21 76.0 3.6 2.4 1 1 1 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 CRK20910.1 - 0.17 12.4 0.3 0.17 12.4 0.3 2.4 2 1 0 2 2 2 0 PAP2 superfamily C-terminal RGS PF00615.19 CRK20911.1 - 1.9e-08 34.6 0.0 3.5e-06 27.3 0.0 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain SnoaL_2 PF12680.7 CRK20912.1 - 0.00018 22.1 0.0 0.00023 21.7 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.6 CRK20912.1 - 0.024 14.8 0.0 0.036 14.2 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like domain DHDPS PF00701.22 CRK20913.1 - 5.6e-48 163.1 0.0 6.7e-48 162.9 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Aminotran_1_2 PF00155.21 CRK20914.1 - 2.7e-68 230.8 0.0 3.1e-68 230.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Tannase PF07519.11 CRK20916.1 - 4.2e-93 312.8 0.0 5.8e-93 312.3 0.0 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 CRK20916.1 - 0.033 13.4 0.0 0.071 12.4 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 COesterase PF00135.28 CRK20917.1 - 2.2e-82 277.6 0.0 7.6e-73 246.1 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 CRK20917.1 - 7.9e-11 42.2 0.0 1.4e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Zn_clus PF00172.18 CRK20919.1 - 4.7e-09 36.2 11.9 8e-09 35.5 11.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DivIC PF04977.15 CRK20919.1 - 0.14 11.9 5.8 1.3 8.9 0.2 2.3 2 0 0 2 2 2 0 Septum formation initiator ZapB PF06005.12 CRK20919.1 - 0.43 11.0 6.6 1.2 9.6 3.0 2.2 2 0 0 2 2 2 0 Cell division protein ZapB DAO PF01266.24 CRK20920.1 - 2.1e-31 109.8 7.1 2.4e-31 109.6 7.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase AA_permease_2 PF13520.6 CRK20922.1 - 1.5e-80 271.1 26.6 1.8e-80 270.8 26.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CRK20922.1 - 3.9e-22 78.5 23.1 4.8e-22 78.2 23.1 1.1 1 0 0 1 1 1 1 Amino acid permease Aa_trans PF01490.18 CRK20922.1 - 3.3 6.3 18.7 0.38 9.4 10.5 2.9 2 1 0 2 2 2 0 Transmembrane amino acid transporter protein DUF2235 PF09994.9 CRK20923.1 - 1.3e-100 336.5 0.0 1.6e-100 336.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) An_peroxidase PF03098.15 CRK20925.1 - 4.5e-16 58.5 0.1 1.4e-08 33.8 0.0 2.2 1 1 1 2 2 2 2 Animal haem peroxidase PI_PP_C PF18365.1 CRK20925.1 - 0.019 14.9 0.1 0.035 14.1 0.1 1.3 1 0 0 1 1 1 0 Phosphoinositide phosphatase C-terminal domain Unstab_antitox PF09720.10 CRK20925.1 - 0.2 11.7 0.2 0.46 10.6 0.2 1.6 1 0 0 1 1 1 0 Putative addiction module component Guanylate_kin PF00625.21 CRK20926.1 - 1.7e-30 106.1 0.2 1.8e-30 106.0 0.2 1.0 1 0 0 1 1 1 1 Guanylate kinase Spc29 PF17082.5 CRK20926.1 - 0.12 12.2 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Spindle Pole Component 29 ILVD_EDD PF00920.21 CRK20951.1 - 1.2e-65 222.1 0.0 1.3e-65 222.0 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family zf-UBR PF02207.20 CRK20956.1 - 2.5e-20 72.4 12.7 5.1e-20 71.4 12.7 1.5 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 CRK20956.1 - 7.6e-06 25.6 0.3 2.6e-05 23.9 0.1 2.0 3 0 0 3 3 3 1 ATP-dependent Clp protease adaptor protein ClpS Aconitase PF00330.20 CRK20959.1 - 1.3e-35 123.3 0.0 1.3e-35 123.3 0.0 1.0 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Anticodon_1 PF08264.13 CRK20959.1 - 1.7e-11 44.3 0.0 2.2e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA DUF2013 PF09431.10 CRK20961.1 - 5.4e-49 165.9 1.2 6.3e-49 165.7 1.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) HNF-1A_C PF04813.12 CRK20962.1 - 0.0018 19.0 1.3 0.0018 19.0 1.3 1.8 1 1 0 2 2 2 1 Hepatocyte nuclear factor 1 (HNF-1), alpha isoform C terminus NFACT-C PF11923.8 CRK20963.1 - 2.8e-36 123.6 0.2 2.8e-36 123.6 0.2 2.1 1 1 1 2 2 2 1 NFACT protein C-terminal domain Pox_G7 PF05503.12 CRK20963.1 - 0.038 12.9 0.1 0.047 12.6 0.1 1.1 1 0 0 1 1 1 0 Poxvirus G7-like PRA-PH PF01503.17 CRK20963.1 - 0.062 13.7 2.6 0.071 13.6 1.9 1.8 1 1 0 1 1 1 0 Phosphoribosyl-ATP pyrophosphohydrolase DUF1764 PF08576.10 CRK20963.1 - 0.59 11.1 6.4 0.17 12.8 3.8 1.4 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) Pannexin_like PF12534.8 CRK20963.1 - 5.2 6.0 4.8 7 5.6 4.8 1.1 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 bZIP_2 PF07716.15 CRK20966.1 - 1.7e-06 28.0 6.5 2.7e-06 27.4 6.5 1.2 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 CRK20966.1 - 2e-05 24.6 5.6 3.1e-05 24.0 5.6 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 CRK20966.1 - 0.016 15.7 1.1 0.026 15.0 1.1 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor Fes1 PF08609.10 CRK20966.1 - 0.027 15.3 0.0 0.04 14.8 0.0 1.3 1 0 0 1 1 1 0 Nucleotide exchange factor Fes1 TTKRSYEDQ PF10212.9 CRK20966.1 - 0.047 12.7 0.0 0.062 12.3 0.0 1.1 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein WD40 PF00400.32 CRK20967.1 - 8.1e-23 80.3 24.4 1.4e-05 25.8 0.1 6.9 6 2 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK20967.1 - 3.7e-14 52.8 4.8 6.3e-06 26.4 0.0 3.9 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.7 CRK20967.1 - 6e-05 23.1 6.8 0.014 15.3 0.1 2.7 2 2 0 2 2 2 2 Transcription factor IIIC subunit delta N-term G-patch PF01585.23 CRK20968.1 - 0.0034 17.3 0.6 0.011 15.6 0.6 1.9 1 0 0 1 1 1 1 G-patch domain RCC1_2 PF13540.6 CRK20968.1 - 0.013 15.3 0.3 5.6 6.9 0.1 2.6 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat GSDH PF07995.11 CRK20968.1 - 0.11 11.8 1.0 0.31 10.3 1.0 1.7 1 1 0 1 1 1 0 Glucose / Sorbosone dehydrogenase Pkinase PF00069.25 CRK20969.1 - 5.8e-60 202.9 0.0 1.2e-59 201.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK20969.1 - 2e-35 122.3 0.0 5.8e-35 120.8 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 CRK20969.1 - 9.8e-21 73.3 0.3 1.9e-20 72.4 0.3 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Haspin_kinase PF12330.8 CRK20969.1 - 2.5e-07 30.0 0.3 1.1e-06 27.9 0.3 1.9 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CRK20969.1 - 2.6e-06 27.0 0.0 4.5e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CRK20969.1 - 1.7e-05 24.3 0.1 3.3e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CRK20969.1 - 0.0015 18.5 0.0 0.011 15.7 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 CRK20969.1 - 0.016 14.8 1.1 0.038 13.6 0.0 2.1 2 0 0 2 2 2 0 RIO1 family YrbL-PhoP_reg PF10707.9 CRK20969.1 - 0.067 12.7 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL WaaY PF06176.11 CRK20969.1 - 0.1 12.2 0.1 0.16 11.5 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Rcd1 PF04078.13 CRK20971.1 - 9.1e-90 300.4 4.2 3.4e-84 282.2 0.5 2.1 1 1 1 2 2 2 2 Cell differentiation family, Rcd1-like baeRF_family10 PF18854.1 CRK20971.1 - 0.36 11.1 3.3 12 6.2 0.3 2.6 2 1 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 10 CIA30 PF08547.12 CRK20972.1 - 2.9e-38 131.4 0.0 3.6e-38 131.1 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Homoserine_dh PF00742.19 CRK20973.1 - 1e-51 175.3 0.0 1.4e-51 174.9 0.0 1.1 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 CRK20973.1 - 4e-08 33.9 0.0 2.1e-07 31.6 0.0 2.0 1 1 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DUF1295 PF06966.12 CRK20974.1 - 3.7e-29 101.9 0.1 2.9e-27 95.7 0.1 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) FBPase PF00316.20 CRK20975.1 - 2.4e-70 235.8 0.1 3.3e-70 235.4 0.1 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain PEX11 PF05648.14 CRK20976.1 - 2.6e-48 164.4 2.2 8e-26 90.9 0.0 2.0 1 1 1 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) PXA PF02194.15 CRK20977.1 - 5e-52 176.5 2.6 1.1e-51 175.5 0.3 2.7 3 0 0 3 3 3 1 PXA domain Nexin_C PF08628.12 CRK20977.1 - 2.5e-21 76.3 0.6 8.3e-21 74.7 0.2 2.1 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.24 CRK20977.1 - 4.3e-18 65.3 0.4 1.2e-17 63.9 0.4 1.8 1 0 0 1 1 1 1 PX domain RGS PF00615.19 CRK20977.1 - 1.2e-12 48.1 0.1 3.2e-12 46.8 0.1 1.8 1 0 0 1 1 1 1 Regulator of G protein signaling domain RRM_1 PF00076.22 CRK20977.1 - 2.9e-06 27.0 0.0 7.9e-06 25.6 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_4 PF02390.17 CRK20978.1 - 2.4e-55 186.7 0.0 3.4e-55 186.1 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 CRK20978.1 - 5.7e-05 23.8 0.0 0.0002 22.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK20978.1 - 0.00053 20.7 0.0 0.0013 19.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK20978.1 - 0.0023 17.8 0.0 0.0043 16.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CRK20978.1 - 0.0076 15.8 0.0 0.013 15.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 CRK20978.1 - 0.019 14.8 0.0 0.034 13.9 0.0 1.5 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 CRK20978.1 - 0.021 14.8 0.0 0.04 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 CRK20978.1 - 0.037 14.7 0.1 0.15 12.7 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain DUF5534 PF17686.1 CRK20979.1 - 0.11 12.8 0.0 0.15 12.3 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5534) PXA PF02194.15 CRK20980.1 - 2.1e-53 181.0 0.8 9.6e-53 178.9 0.2 2.6 3 0 0 3 3 3 1 PXA domain Methyltransf_4 PF02390.17 CRK20980.1 - 1.1e-39 135.7 0.1 2.1e-39 134.8 0.1 1.4 1 0 0 1 1 1 1 Putative methyltransferase Nexin_C PF08628.12 CRK20980.1 - 1.1e-29 103.3 0.3 3.4e-29 101.7 0.3 2.0 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.24 CRK20980.1 - 3.6e-21 75.3 0.3 9e-21 74.0 0.3 1.7 1 0 0 1 1 1 1 PX domain RGS PF00615.19 CRK20980.1 - 1.7e-11 44.4 0.1 4.6e-11 43.0 0.1 1.8 1 0 0 1 1 1 1 Regulator of G protein signaling domain DUF5534 PF17686.1 CRK20981.1 - 0.13 12.5 0.1 0.2 11.9 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5534) BCS1_N PF08740.11 CRK20984.1 - 2.2e-56 190.8 1.5 2.2e-56 190.8 1.5 2.3 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.29 CRK20984.1 - 3.3e-17 63.2 0.0 1.7e-14 54.4 0.0 2.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CRK20984.1 - 0.0078 16.0 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CRK20984.1 - 0.047 13.7 0.0 0.34 10.9 0.0 2.5 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) VirB3 PF05101.13 CRK20984.1 - 0.1 12.8 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein AAA_11 PF13086.6 CRK20984.1 - 0.12 12.1 8.0 30 4.3 9.3 2.3 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CRK20984.1 - 0.22 11.9 0.0 0.22 11.9 0.0 2.6 2 1 1 3 3 2 0 AAA ATPase domain DUF3362 PF11842.8 CRK20984.1 - 0.44 10.9 7.9 25 5.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3362) RNA12 PF10443.9 CRK20984.1 - 0.63 8.7 8.6 0.52 9.0 6.9 1.6 2 0 0 2 2 2 0 RNA12 protein FAM176 PF14851.6 CRK20984.1 - 1.2 8.8 14.9 18 5.0 0.0 2.5 2 0 0 2 2 2 0 FAM176 family Atrophin-1 PF03154.15 CRK20984.1 - 1.5 7.0 19.6 2.2 6.5 19.6 1.1 1 0 0 1 1 1 0 Atrophin-1 family Presenilin PF01080.17 CRK20984.1 - 2.4 6.8 7.5 4.5 5.9 7.5 1.4 1 0 0 1 1 1 0 Presenilin DUF2052 PF09747.9 CRK20984.1 - 2.6 8.1 20.9 1.2 9.2 14.4 2.5 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) DDHD PF02862.17 CRK20984.1 - 4.2 7.5 5.5 11 6.1 5.5 1.7 1 0 0 1 1 1 0 DDHD domain DDRGK PF09756.9 CRK20984.1 - 6.5 6.3 30.2 17 5.0 0.0 2.4 2 0 0 2 2 2 0 DDRGK domain Vfa1 PF08432.10 CRK20984.1 - 7.4 6.9 20.9 4.3 7.6 17.4 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 TLP-20 PF06088.11 CRK20984.1 - 9.3 6.1 10.4 30 4.4 7.0 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) FAD_binding_4 PF01565.23 CRK20985.1 - 3.2e-13 49.6 0.0 5e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain BCS1_N PF08740.11 CRK20987.1 - 2.2e-32 112.5 5.5 1.5e-31 109.8 0.2 2.3 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.29 CRK20987.1 - 2.2e-17 63.7 0.0 1.3e-14 54.8 0.0 2.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CRK20987.1 - 0.0065 16.2 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CRK20987.1 - 0.029 14.7 0.4 0.16 12.3 0.4 2.2 1 1 0 1 1 1 0 AAA ATPase domain Atrophin-1 PF03154.15 CRK20987.1 - 0.038 12.3 15.7 0.055 11.8 15.7 1.1 1 0 0 1 1 1 0 Atrophin-1 family AAA_11 PF13086.6 CRK20987.1 - 0.064 13.0 5.0 19 5.0 6.4 2.2 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 CRK20987.1 - 0.064 13.3 0.0 0.3 11.1 0.0 2.1 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) VirB3 PF05101.13 CRK20987.1 - 0.091 13.0 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein FAM176 PF14851.6 CRK20987.1 - 0.15 11.7 10.3 15 5.2 0.0 2.4 2 0 0 2 2 2 0 FAM176 family Presenilin PF01080.17 CRK20987.1 - 0.42 9.3 2.6 0.71 8.6 2.6 1.3 1 0 0 1 1 1 0 Presenilin DUF3362 PF11842.8 CRK20987.1 - 0.54 10.6 6.8 21 5.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3362) RNA12 PF10443.9 CRK20987.1 - 0.63 8.7 7.5 0.55 8.9 5.9 1.6 2 0 0 2 2 2 0 RNA12 protein Vfa1 PF08432.10 CRK20987.1 - 0.99 9.7 15.0 0.35 11.2 11.0 2.0 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 RR_TM4-6 PF06459.12 CRK20987.1 - 3.1 7.6 12.9 6.6 6.5 12.9 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDRGK PF09756.9 CRK20987.1 - 8.8 5.9 23.8 14 5.2 0.0 2.3 2 0 0 2 2 2 0 DDRGK domain WRNPLPNID PF15017.6 CRK20987.1 - 9.4 7.2 12.2 58 4.7 8.2 2.5 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box HMG_CoA_synt_C PF08540.10 CRK20988.1 - 5.8e-104 347.6 0.8 7.2e-104 347.3 0.8 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 CRK20988.1 - 1.4e-94 314.8 0.2 2.1e-94 314.3 0.2 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal Abhydrolase_3 PF07859.13 CRK20989.1 - 1.4e-45 155.7 0.1 4.4e-45 154.1 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Pex14_N PF04695.13 CRK20989.1 - 3.5e-31 109.0 0.3 3.5e-31 109.0 0.3 3.4 2 1 0 2 2 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Say1_Mug180 PF10340.9 CRK20989.1 - 0.00034 19.6 0.0 0.001 18.0 0.0 1.7 1 1 0 1 1 1 1 Steryl acetyl hydrolase FAD_binding_4 PF01565.23 CRK20989.1 - 0.00066 19.4 0.0 0.0015 18.3 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain zf-C4H2 PF10146.9 CRK20989.1 - 0.0026 18.1 0.6 0.0026 18.1 0.6 2.1 2 0 0 2 2 2 1 Zinc finger-containing protein ERM PF00769.19 CRK20989.1 - 0.012 15.4 1.4 0.012 15.4 1.4 2.1 2 0 0 2 2 2 0 Ezrin/radixin/moesin family UPF0242 PF06785.11 CRK20989.1 - 0.03 14.4 3.2 0.063 13.4 3.2 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF1043 PF06295.12 CRK20989.1 - 0.13 12.3 0.8 0.33 11.0 0.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF16 PF01519.16 CRK20989.1 - 0.27 11.7 2.0 14 6.2 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF572 PF04502.13 CRK20989.1 - 0.28 10.7 3.1 0.49 10.0 3.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Prominin PF05478.11 CRK20989.1 - 0.3 9.0 0.4 0.44 8.4 0.4 1.1 1 0 0 1 1 1 0 Prominin Lebercilin PF15619.6 CRK20989.1 - 1.6 8.3 8.0 4.1 7.0 8.0 1.6 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease DUF3584 PF12128.8 CRK20989.1 - 1.7 6.1 9.7 2.6 5.5 9.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Ndc1_Nup PF09531.10 CRK20989.1 - 5.1 5.7 5.4 8.9 4.9 5.4 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Ndc80_HEC PF03801.13 CRK20990.1 - 1.7e-87 290.8 2.2 1.3e-61 206.7 0.7 2.5 2 0 0 2 2 2 2 HEC/Ndc80p family Lactamase_B_2 PF12706.7 CRK20990.1 - 1.3e-26 93.4 0.0 3.9e-26 91.8 0.0 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 CRK20990.1 - 2.6e-08 33.9 0.1 8.3e-08 32.3 0.0 1.9 2 0 0 2 2 1 1 Beta-lactamase superfamily domain YmzC PF14157.6 CRK20990.1 - 0.00024 21.1 0.1 1.4 9.1 0.0 2.9 2 0 0 2 2 2 2 YmzC-like protein CAT PF00302.18 CRK20990.1 - 0.0035 17.3 0.2 2.6 7.9 0.0 2.5 2 0 0 2 2 2 2 Chloramphenicol acetyltransferase DUF4391 PF14335.6 CRK20990.1 - 0.015 15.0 15.0 0.34 10.6 4.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4391) Fungal_TACC PF12709.7 CRK20990.1 - 0.021 15.2 0.3 0.29 11.6 0.0 7.5 7 2 2 9 9 9 0 Fungal Transforming acidic coiled-coil (TACC) proteins FliJ PF02050.16 CRK20990.1 - 0.025 14.8 41.1 0.27 11.5 2.6 5.4 4 1 1 5 5 5 0 Flagellar FliJ protein Anth_Ig PF05587.13 CRK20990.1 - 0.029 14.7 0.0 5.8 7.3 0.0 2.5 2 0 0 2 2 2 0 Anthrax receptor extracellular domain Spiralin PF05215.13 CRK20990.1 - 0.041 13.2 1.6 1.4 8.2 0.2 2.4 2 0 0 2 2 2 0 Spiralin DUF2935 PF11155.8 CRK20990.1 - 0.11 12.8 10.3 2.2 8.6 0.0 4.5 4 3 0 4 4 4 0 Domain of unknown function (DUF2935) BLYB PF05289.11 CRK20990.1 - 0.21 11.8 15.7 0.44 10.8 0.9 3.3 3 0 0 3 3 2 0 Borrelia hemolysin accessory protein Lactamase_B PF00753.27 CRK20990.1 - 0.27 11.2 3.4 0.81 9.7 3.4 1.9 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily ERM PF00769.19 CRK20990.1 - 2.7 7.7 64.6 0.12 12.2 11.2 4.4 4 0 0 4 4 4 0 Ezrin/radixin/moesin family VIT1 PF01988.19 CRK20991.1 - 1.7e-60 204.6 5.9 1.7e-60 204.6 5.9 1.9 2 0 0 2 2 2 1 VIT family Rad10 PF03834.14 CRK20991.1 - 6e-46 155.2 0.0 9.5e-46 154.5 0.0 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 CRK20991.1 - 0.05 14.2 0.1 0.11 13.2 0.1 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix domain DNA_pol_alpha_N PF12254.8 CRK20992.1 - 0.043 13.9 0.1 0.057 13.5 0.1 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal Spermine_synth PF01564.17 CRK20993.1 - 1.5e-09 37.6 0.0 2.6e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_23 PF13489.6 CRK20993.1 - 0.0047 16.8 0.0 0.013 15.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain AlaDh_PNT_C PF01262.21 CRK20993.1 - 0.1 11.9 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyridox_ox_2 PF12900.7 CRK20994.1 - 3.7e-31 108.0 0.0 5.2e-31 107.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF4482 PF14818.6 CRK20995.1 - 0.19 12.6 7.3 0.96 10.3 7.3 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4482) Mito_fiss_reg PF05308.11 CRK20997.1 - 0.67 10.0 4.2 1.1 9.2 4.2 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 CRK20997.1 - 9.8 5.5 7.8 19 4.6 7.8 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal ABC_tran PF00005.27 CRK20998.1 - 4.6e-49 166.5 0.2 5.5e-23 82.0 0.0 3.4 3 0 0 3 3 3 2 ABC transporter Tubulin PF00091.25 CRK20998.1 - 4.6e-24 85.7 0.0 1.1e-23 84.5 0.0 1.6 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain ABC_tran_Xtn PF12848.7 CRK20998.1 - 3.5e-21 75.0 6.2 3.5e-21 75.0 6.2 3.5 4 0 0 4 4 3 1 ABC transporter AAA_21 PF13304.6 CRK20998.1 - 1.9e-18 67.3 0.3 0.00014 21.8 0.0 4.4 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CRK20998.1 - 3.8e-10 39.6 4.5 0.0091 15.5 0.0 4.6 5 0 0 5 5 4 3 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 CRK20998.1 - 1.8e-06 28.3 0.0 0.024 14.9 0.0 3.3 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.23 CRK20998.1 - 2.8e-06 27.4 0.0 0.037 14.1 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.6 CRK20998.1 - 3.8e-06 27.5 0.1 0.16 12.5 0.0 3.3 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.6 CRK20998.1 - 6.3e-06 25.8 0.4 0.086 12.6 0.0 3.2 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 CRK20998.1 - 1.3e-05 25.6 1.1 0.066 13.6 0.1 3.0 3 0 0 3 3 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 CRK20998.1 - 1.7e-05 24.8 1.7 0.13 12.1 0.0 3.4 2 1 1 3 3 3 2 RsgA GTPase AAA_30 PF13604.6 CRK20998.1 - 2.2e-05 24.3 1.5 0.0054 16.5 0.0 3.5 4 0 0 4 4 4 1 AAA domain AAA_23 PF13476.6 CRK20998.1 - 3.4e-05 24.4 15.6 0.036 14.6 0.0 4.6 5 0 0 5 5 4 2 AAA domain Misat_Tub_SegII PF10644.9 CRK20998.1 - 4.1e-05 23.9 0.3 0.00016 22.0 0.0 2.2 2 0 0 2 2 1 1 Misato Segment II tubulin-like domain AAA_28 PF13521.6 CRK20998.1 - 5.1e-05 23.6 0.1 0.081 13.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CRK20998.1 - 0.00017 21.7 0.6 0.87 9.7 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA PF00004.29 CRK20998.1 - 0.00022 21.6 0.0 1.3 9.5 0.1 3.0 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 CRK20998.1 - 0.00044 20.0 2.1 1 9.1 0.1 3.7 3 1 0 3 3 3 2 AAA domain Dynamin_N PF00350.23 CRK20998.1 - 0.002 18.2 5.1 3.3 7.8 0.1 4.2 4 1 0 4 4 4 2 Dynamin family AAA_14 PF13173.6 CRK20998.1 - 0.0022 18.0 0.0 2.6 8.1 0.0 2.9 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 CRK20998.1 - 0.004 17.1 0.1 2 8.3 0.0 2.6 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.22 CRK20998.1 - 0.0054 17.1 0.0 6.4 7.2 0.0 2.6 2 0 0 2 2 2 0 RNA helicase NTPase_1 PF03266.15 CRK20998.1 - 0.0058 16.6 0.0 0.89 9.4 0.0 2.7 2 0 0 2 2 2 1 NTPase cobW PF02492.19 CRK20998.1 - 0.0059 16.2 0.3 1.5 8.4 0.4 2.8 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_27 PF13514.6 CRK20998.1 - 0.0094 15.6 0.7 7.1 6.2 0.0 3.8 4 0 0 4 4 3 0 AAA domain AAA_15 PF13175.6 CRK20998.1 - 0.01 15.5 10.7 0.36 10.5 0.0 4.0 5 0 0 5 5 4 0 AAA ATPase domain Roc PF08477.13 CRK20998.1 - 0.012 15.8 0.1 2.1 8.6 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 CRK20998.1 - 0.015 15.3 0.0 4.5 7.3 0.0 2.9 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 CRK20998.1 - 0.016 15.2 0.2 4.1 7.4 0.0 2.9 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) ATP-synt_ab PF00006.25 CRK20998.1 - 0.019 14.7 0.0 0.97 9.1 0.0 3.0 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain MeaB PF03308.16 CRK20998.1 - 0.021 13.8 1.7 2.2 7.2 0.0 2.8 3 0 0 3 3 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_7 PF12775.7 CRK20998.1 - 0.031 13.8 0.0 10 5.6 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region SRP54 PF00448.22 CRK20998.1 - 0.042 13.5 0.1 6.5 6.3 0.1 2.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MobB PF03205.14 CRK20998.1 - 0.051 13.5 0.3 1.4 8.8 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.12 CRK20998.1 - 0.065 12.5 2.5 7.2 5.8 0.0 4.0 4 1 0 4 4 4 0 Zeta toxin Thymidylate_kin PF02223.17 CRK20998.1 - 0.068 12.8 0.7 2.1 8.0 0.0 3.4 3 0 0 3 3 3 0 Thymidylate kinase SbcCD_C PF13558.6 CRK20998.1 - 0.13 12.5 0.5 12 6.2 0.2 3.4 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF87 PF01935.17 CRK20998.1 - 0.18 11.8 7.0 1 9.4 0.1 3.7 4 0 0 4 4 3 0 Helicase HerA, central domain AAA_17 PF13207.6 CRK20998.1 - 0.81 10.1 7.8 33 4.9 0.2 4.1 4 1 0 4 4 3 0 AAA domain Fmp27_WPPW PF10359.9 CRK20998.1 - 3.1 6.5 8.2 2.7 6.7 0.8 2.9 3 0 0 3 3 3 0 RNA pol II promoter Fmp27 protein domain Inositol_P PF00459.25 CRK20999.1 - 1.3e-34 119.9 0.1 3.5e-34 118.6 0.1 1.5 1 1 0 1 1 1 1 Inositol monophosphatase family DUF2630 PF10944.8 CRK20999.1 - 0.0024 18.3 0.7 0.0044 17.4 0.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2630) HTH_8 PF02954.19 CRK20999.1 - 0.019 14.7 0.9 0.087 12.6 0.0 2.2 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family Tubulin_C PF03953.17 CRK21000.1 - 1.1e-13 51.4 0.1 1.5e-13 51.0 0.1 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain Ribosomal_L6 PF00347.23 CRK21001.1 - 7.6e-22 77.8 0.0 2.1e-10 41.1 0.0 3.1 3 1 0 3 3 3 2 Ribosomal protein L6 p450 PF00067.22 CRK21002.1 - 2.8e-59 201.1 0.0 4.7e-59 200.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Inositol_P PF00459.25 CRK21002.1 - 2.5e-21 76.4 0.5 3e-19 69.6 0.1 2.2 1 1 1 2 2 2 2 Inositol monophosphatase family Methyltransf_23 PF13489.6 CRK21003.1 - 3.7e-18 65.9 0.0 5.8e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK21003.1 - 3.8e-10 40.3 0.0 2e-09 38.0 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK21003.1 - 7.9e-08 33.0 0.0 4.3e-07 30.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CRK21003.1 - 9.1e-08 32.6 0.0 3.9e-07 30.6 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK21003.1 - 5.6e-05 23.0 0.0 0.0006 19.6 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 CRK21003.1 - 0.00023 20.7 0.0 0.0008 18.9 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 CRK21003.1 - 0.0028 17.0 0.0 0.038 13.3 0.0 2.1 2 0 0 2 2 2 1 O-methyltransferase domain Methyltransf_16 PF10294.9 CRK21003.1 - 0.0095 15.7 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 CRK21003.1 - 0.012 15.1 0.0 0.042 13.4 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain FtsJ PF01728.19 CRK21003.1 - 0.052 13.6 0.0 0.079 13.1 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase UTRA PF07702.13 CRK21004.1 - 0.19 11.6 0.1 0.27 11.1 0.1 1.1 1 0 0 1 1 1 0 UTRA domain Aha1_N PF09229.11 CRK21006.1 - 6.6e-40 136.5 0.2 1.5e-39 135.3 0.2 1.7 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal Rap1_C PF11626.8 CRK21006.1 - 2.9e-26 91.4 0.2 1.1e-23 83.1 0.0 2.9 2 0 0 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.11 CRK21006.1 - 1.8e-25 88.9 3.2 1.1e-13 51.1 0.2 2.8 2 0 0 2 2 2 2 Rap1 Myb domain AHSA1 PF08327.11 CRK21006.1 - 4.3e-20 72.2 0.1 1.3e-19 70.6 0.1 1.9 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein BRCT_2 PF16589.5 CRK21006.1 - 3.8e-09 36.8 0.0 1.4e-08 35.0 0.0 2.0 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain Rap1-DNA-bind PF09197.10 CRK21006.1 - 2.1e-08 34.7 0.6 0.0083 16.7 0.0 3.3 2 0 0 2 2 2 2 Rap1, DNA-binding ARID PF01388.21 CRK21006.1 - 2.7e-08 34.4 0.0 1e-07 32.5 0.0 2.1 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain DHHC PF01529.20 CRK21007.1 - 1.7e-30 105.8 3.8 1.7e-30 105.8 3.8 2.4 3 0 0 3 3 3 1 DHHC palmitoyltransferase CN_hydrolase PF00795.22 CRK21008.1 - 8e-25 87.7 0.0 1.3e-24 87.0 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Tht1 PF04163.12 CRK21008.1 - 4e-06 25.9 1.4 9.7e-06 24.6 1.4 1.5 1 1 0 1 1 1 1 Tht1-like nuclear fusion protein CLZ PF16526.5 CRK21008.1 - 0.11 12.9 1.9 0.16 12.3 0.3 2.1 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF2937 PF11157.8 CRK21008.1 - 0.37 10.5 2.5 0.74 9.5 0.2 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2937) SKA2 PF16740.5 CRK21008.1 - 0.81 9.5 6.1 0.31 10.9 1.5 2.3 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 Helo_like_N PF17111.5 CRK21008.1 - 3.2 7.1 7.9 7.5 5.9 0.7 2.9 1 1 2 3 3 3 0 Fungal N-terminal domain of STAND proteins Baculo_PEP_C PF04513.12 CRK21008.1 - 3.9 7.5 11.3 1.7 8.7 6.8 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus APG6_N PF17675.1 CRK21008.1 - 5 7.7 7.7 5 7.7 0.7 2.4 1 1 0 2 2 2 0 Apg6 coiled-coil region Fib_alpha PF08702.10 CRK21008.1 - 6 7.0 6.3 14 5.8 0.1 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family HLH PF00010.26 CRK21009.1 - 2e-15 56.5 0.0 4.7e-15 55.3 0.0 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SR-25 PF10500.9 CRK21009.1 - 0.99 9.0 11.1 2.9 7.4 7.3 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Fez1 PF06818.15 CRK21009.1 - 4.3 7.7 6.7 6.9 7.1 6.7 1.2 1 0 0 1 1 1 0 Fez1 Peptidase_M24 PF00557.24 CRK21010.1 - 2.2e-51 174.5 0.0 3.2e-51 174.0 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 CRK21010.1 - 1.1e-35 122.0 0.0 1.7e-35 121.4 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Dfp1_Him1_M PF08630.10 CRK21012.1 - 2.3e-42 144.2 0.2 7.8e-42 142.5 0.0 2.1 2 0 0 2 2 2 1 Dfp1/Him1, central region zf-DBF PF07535.12 CRK21012.1 - 1.4e-20 73.2 0.3 2.1e-20 72.5 0.3 1.3 1 0 0 1 1 1 1 DBF zinc finger PTCB-BRCT PF12738.7 CRK21012.1 - 0.0059 16.5 0.0 0.028 14.4 0.0 2.0 2 0 0 2 2 2 1 twin BRCT domain APG12 PF04110.13 CRK21017.1 - 8.5e-27 93.4 0.0 1.2e-26 92.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 CRK21017.1 - 0.0001 22.4 0.0 0.00017 21.7 0.0 1.3 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like DUF1577 PF07614.11 CRK21017.1 - 0.048 12.7 0.0 0.065 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1577) MIIP PF15734.5 CRK21017.1 - 0.25 10.8 1.6 0.37 10.2 1.6 1.2 1 0 0 1 1 1 0 Migration and invasion-inhibitory Pantoate_transf PF02548.15 CRK21019.1 - 1.4e-104 349.1 0.3 1.7e-104 348.9 0.3 1.1 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 CRK21019.1 - 3.8e-07 29.8 0.8 1.2e-06 28.1 0.8 1.8 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase UQ_con PF00179.26 CRK21021.1 - 1.7e-35 121.7 0.2 2.2e-35 121.3 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CRK21021.1 - 0.03 14.6 0.0 0.049 13.9 0.0 1.4 1 0 0 1 1 1 0 RWD domain MFS_5 PF05631.14 CRK21023.1 - 6.6e-72 242.4 5.3 9.9e-32 110.2 0.0 4.3 3 1 1 4 4 4 4 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 CRK21023.1 - 9.8e-20 70.8 94.0 3.3e-11 42.7 22.0 6.6 6 1 0 6 6 6 5 Major Facilitator Superfamily BatD PF13584.6 CRK21023.1 - 0.059 12.2 1.5 0.29 9.9 0.2 2.2 2 0 0 2 2 2 0 Oxygen tolerance Cbl_N PF02262.16 CRK21023.1 - 0.56 10.2 4.4 13 5.8 0.1 3.2 3 0 0 3 3 3 0 CBL proto-oncogene N-terminal domain 1 TMEM154 PF15102.6 CRK21023.1 - 0.75 9.7 2.0 3 7.7 2.0 2.0 1 0 0 1 1 1 0 TMEM154 protein family Tyrosinase PF00264.20 CRK21026.1 - 2.4e-36 126.1 0.3 5e-36 125.1 0.1 1.7 2 0 0 2 2 2 1 Common central domain of tyrosinase DHDPS PF00701.22 CRK21026.1 - 1.4e-32 112.5 0.0 2.4e-32 111.8 0.0 1.2 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family APH PF01636.23 CRK21026.1 - 2.3e-06 27.7 1.4 2.3e-06 27.7 1.4 2.4 2 1 0 2 2 2 1 Phosphotransferase enzyme family Tyosinase_C PF18132.1 CRK21026.1 - 8.3e-06 26.5 0.0 2.6e-05 24.9 0.0 1.9 1 1 0 1 1 1 1 Tyosinase C-terminal domain Glyco_hydro_16 PF00722.21 CRK21031.1 - 8.6e-44 149.1 4.1 1.8e-43 148.1 4.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 FAM176 PF14851.6 CRK21031.1 - 2 8.1 4.9 3.9 7.1 4.9 1.5 1 0 0 1 1 1 0 FAM176 family Mitofilin PF09731.9 CRK21031.1 - 2.3 7.0 9.6 3.1 6.5 9.6 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Apt1 PF10351.9 CRK21031.1 - 8.1 5.2 9.2 12 4.7 9.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain ADH_N PF08240.12 CRK21032.1 - 8.5e-15 54.6 0.9 1.1e-14 54.2 0.9 1.2 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Tyrosinase PF00264.20 CRK21034.1 - 9.4e-37 127.4 0.1 1.7e-36 126.6 0.1 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 CRK21034.1 - 4.7e-07 30.5 0.0 2.1e-06 28.4 0.0 2.0 1 1 0 1 1 1 1 Tyosinase C-terminal domain APH PF01636.23 CRK21037.1 - 2.2e-07 31.1 2.0 6.7e-07 29.5 1.9 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Gloverin PF10793.9 CRK21039.1 - 0.012 15.5 0.0 0.015 15.2 0.0 1.1 1 0 0 1 1 1 0 Gloverin-like protein Glyco_hydro_16 PF00722.21 CRK21041.1 - 3e-35 121.3 4.7 3e-35 121.3 4.7 1.9 2 1 1 3 3 3 1 Glycosyl hydrolases family 16 Plasmodium_Vir PF05795.11 CRK21041.1 - 0.045 13.2 1.4 0.06 12.8 1.4 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Smg8_Smg9 PF10220.9 CRK21041.1 - 0.16 10.3 3.1 0.2 9.9 3.1 1.0 1 0 0 1 1 1 0 Smg8_Smg9 Mitofilin PF09731.9 CRK21041.1 - 0.47 9.2 9.0 0.61 8.9 9.0 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein SURF2 PF05477.11 CRK21041.1 - 1.3 8.7 5.5 1.8 8.2 5.5 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Apt1 PF10351.9 CRK21041.1 - 2.5 6.9 9.2 3.3 6.4 9.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain ADH_zinc_N PF00107.26 CRK21043.1 - 1.4e-20 73.6 0.0 2.4e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CRK21043.1 - 3.4e-20 72.0 4.3 5.9e-20 71.2 4.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 CRK21043.1 - 2.6e-05 25.3 0.0 4.6e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 CRK21043.1 - 0.0045 16.3 0.1 0.0071 15.7 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 CRK21043.1 - 0.021 14.2 0.1 0.033 13.6 0.1 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SIR2 PF02146.17 CRK21046.1 - 1e-18 67.9 0.0 7.7e-10 39.0 0.0 2.1 1 1 1 2 2 2 2 Sir2 family Fungal_trans PF04082.18 CRK21048.1 - 4.1e-13 49.0 0.0 1.9e-12 46.8 0.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK21048.1 - 0.0011 19.0 5.8 0.002 18.2 5.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_zinc_N PF00107.26 CRK21050.1 - 4.8e-21 75.1 0.0 6.4e-21 74.7 0.0 1.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CRK21050.1 - 1.1e-06 29.8 0.0 1.9e-06 29.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 CRK21050.1 - 0.0013 18.1 0.1 0.0018 17.6 0.1 1.1 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 CRK21050.1 - 0.0066 15.8 0.1 0.0093 15.3 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SIR2 PF02146.17 CRK21052.1 - 2.7e-39 134.9 0.0 5.9e-39 133.8 0.0 1.5 1 1 0 1 1 1 1 Sir2 family Fungal_trans PF04082.18 CRK21053.1 - 2e-19 69.7 0.0 5.9e-19 68.1 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK21053.1 - 0.0018 18.4 5.6 0.0031 17.6 5.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-primase PF09329.11 CRK21056.1 - 5.8e-18 64.4 0.7 1.1e-17 63.5 0.7 1.5 1 0 0 1 1 1 1 Primase zinc finger DASH_Duo1 PF08651.10 CRK21058.1 - 2.8e-31 107.1 1.4 4.1e-31 106.6 1.4 1.3 1 0 0 1 1 1 1 DASH complex subunit Duo1 DUF1682 PF07946.14 CRK21058.1 - 0.0018 17.6 4.4 0.002 17.4 4.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Menin PF05053.13 CRK21058.1 - 0.11 10.9 1.6 0.14 10.5 1.6 1.1 1 0 0 1 1 1 0 Menin DASH_Dad2 PF08654.10 CRK21058.1 - 0.7 10.4 5.4 2 8.9 5.4 1.7 1 1 0 1 1 1 0 DASH complex subunit Dad2 Cation_ATPase_C PF00689.21 CRK21061.1 - 1.3e-40 139.0 10.9 1.3e-40 139.0 10.9 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 CRK21061.1 - 9.8e-37 126.2 1.0 9.8e-37 126.2 1.0 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 CRK21061.1 - 1.3e-21 76.5 0.0 2.4e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CRK21061.1 - 2.2e-19 70.6 0.1 9.2e-19 68.6 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CRK21061.1 - 1.7e-05 24.7 0.3 3.4e-05 23.7 0.3 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CRK21061.1 - 0.00015 21.4 0.0 0.0004 20.0 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.7 CRK21061.1 - 0.09 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase SIR2 PF02146.17 CRK21063.1 - 2.1e-56 190.6 0.0 3.1e-56 190.1 0.0 1.2 1 0 0 1 1 1 1 Sir2 family Med16 PF11635.8 CRK21063.1 - 0.035 12.0 0.0 0.049 11.6 0.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 16 DUF592 PF04574.13 CRK21063.1 - 0.097 12.4 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF592) Pkinase PF00069.25 CRK21064.1 - 8.2e-18 64.7 0.0 3.8e-17 62.5 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK21064.1 - 5.6e-11 42.2 0.0 3.8e-10 39.5 0.0 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase DCB PF16213.5 CRK21064.1 - 0.00011 22.0 0.0 0.02 14.6 0.0 2.6 2 0 0 2 2 2 2 Dimerisation and cyclophilin-binding domain of Mon2 Aminotran_4 PF01063.19 CRK21065.1 - 2.4e-34 119.1 0.0 3.8e-34 118.5 0.0 1.3 1 0 0 1 1 1 1 Amino-transferase class IV ESSS PF10183.9 CRK21066.1 - 9.7e-11 41.8 0.0 1.6e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) FUSC_2 PF13515.6 CRK21067.1 - 2.6e-14 53.5 27.9 3.7e-13 49.7 10.1 2.5 2 0 0 2 2 2 2 Fusaric acid resistance protein-like ArAE_2_N PF10337.9 CRK21067.1 - 4.3e-08 32.6 1.2 4.3e-08 32.6 1.2 3.5 3 1 1 4 4 4 2 Putative ER transporter, 6TM, N-terminal ArAE_2 PF10334.9 CRK21067.1 - 1.5e-05 24.9 0.0 3.5e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 ArAE_1 PF06081.11 CRK21067.1 - 0.00048 20.3 0.4 0.00048 20.3 0.4 3.1 3 0 0 3 3 3 1 Aromatic acid exporter family member 1 ALMT PF11744.8 CRK21067.1 - 0.014 14.3 0.7 0.028 13.3 0.7 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF1097 PF06496.11 CRK21067.1 - 2 8.6 27.2 1 9.5 3.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1097) YibE_F PF07907.11 CRK21067.1 - 3.1 7.2 11.5 5.5 6.4 2.0 2.7 2 1 0 2 2 2 0 YibE/F-like protein FUSC PF04632.12 CRK21067.1 - 3.8 5.9 31.6 0.025 13.1 12.8 3.4 2 2 0 2 2 2 0 Fusaric acid resistance protein family FUSC_2 PF13515.6 CRK21069.1 - 1.9e-10 41.0 8.3 3e-10 40.3 8.3 1.3 1 0 0 1 1 1 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 CRK21069.1 - 3.3e-06 27.1 0.0 5.8e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 ArAE_1 PF06081.11 CRK21069.1 - 0.019 15.1 1.5 0.029 14.5 1.5 1.3 1 0 0 1 1 1 0 Aromatic acid exporter family member 1 ALMT PF11744.8 CRK21069.1 - 0.052 12.4 0.0 0.073 11.9 0.0 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter FUSC-like PF12805.7 CRK21069.1 - 0.11 11.6 3.5 0.23 10.5 3.5 1.6 1 1 0 1 1 1 0 FUSC-like inner membrane protein yccS FUSC PF04632.12 CRK21069.1 - 0.15 10.6 12.3 0.042 12.4 9.0 1.8 1 1 1 2 2 2 0 Fusaric acid resistance protein family DUF1097 PF06496.11 CRK21069.1 - 0.17 12.0 6.0 0.33 11.1 6.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1097) AAA_12 PF13087.6 CRK21070.1 - 3.9e-52 176.8 0.0 5.5e-52 176.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CRK21070.1 - 1.5e-33 116.7 0.2 1.9e-17 63.9 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 CRK21070.1 - 7.3e-15 55.2 0.0 2.3e-14 53.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CRK21070.1 - 8e-13 49.0 0.0 1.8e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 CRK21070.1 - 9.4e-08 32.1 0.6 0.22 11.3 0.0 3.4 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 CRK21070.1 - 0.00019 21.3 0.0 0.00068 19.5 0.0 1.9 1 1 0 1 1 1 1 Helicase UvrD-helicase PF00580.21 CRK21070.1 - 0.00031 20.3 0.0 0.00054 19.6 0.0 1.4 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain SRP54 PF00448.22 CRK21070.1 - 0.0009 18.9 0.1 0.0016 18.1 0.1 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain PIF1 PF05970.14 CRK21070.1 - 0.0014 17.9 0.1 0.077 12.1 0.1 2.1 2 0 0 2 2 2 1 PIF1-like helicase AAA_16 PF13191.6 CRK21070.1 - 0.0024 18.3 0.1 0.0079 16.6 0.0 1.9 2 0 0 2 2 1 1 AAA ATPase domain CbiA PF01656.23 CRK21070.1 - 0.0093 16.0 0.1 0.021 14.9 0.1 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_7 PF12775.7 CRK21070.1 - 0.013 15.0 0.1 0.026 14.0 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ResIII PF04851.15 CRK21070.1 - 0.025 14.6 0.1 0.065 13.2 0.1 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF87 PF01935.17 CRK21070.1 - 0.038 14.1 0.2 0.077 13.1 0.2 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain RuvB_N PF05496.12 CRK21070.1 - 0.04 13.7 0.0 0.071 12.9 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain cobW PF02492.19 CRK21070.1 - 0.053 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 CRK21070.1 - 0.062 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 CRK21070.1 - 0.077 12.9 0.2 0.15 11.9 0.2 1.4 1 0 0 1 1 1 0 NTPase MeaB PF03308.16 CRK21070.1 - 0.1 11.6 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 CRK21070.1 - 0.12 12.0 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 CRK21070.1 - 0.12 12.8 0.1 0.28 11.6 0.1 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 CRK21070.1 - 0.16 11.2 0.0 0.35 10.1 0.0 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PEPCK_ATP PF01293.20 CRK21070.1 - 0.24 10.1 0.0 0.39 9.3 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase Dna2 PF08696.11 CRK21072.1 - 1.7e-49 168.4 2.0 3.2e-41 141.4 0.1 2.9 2 1 1 3 3 3 2 DNA replication factor Dna2 Cas_Cas4 PF01930.17 CRK21072.1 - 2.9e-11 43.7 0.8 5.7e-10 39.5 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF83 Tnp_zf-ribbon_2 PF13842.6 CRK21072.1 - 0.14 13.0 1.0 0.31 11.9 1.0 1.5 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon Thiolase_N PF00108.23 CRK21075.1 - 1.9e-61 207.7 4.8 2.9e-53 180.9 3.2 2.2 1 1 1 2 2 2 2 Thiolase, N-terminal domain Thiolase_C PF02803.18 CRK21075.1 - 5.2e-41 139.1 0.1 1.1e-40 138.2 0.1 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.10 CRK21075.1 - 0.012 15.8 0.0 0.041 14.1 0.0 1.9 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal RTA1 PF04479.13 CRK21077.1 - 2.6e-65 219.9 11.8 2.6e-65 219.9 11.8 1.6 2 0 0 2 2 2 1 RTA1 like protein Phi-29_GP16_7 PF06720.11 CRK21077.1 - 0.13 12.1 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage phi-29 early protein GP16.7 Ssu72 PF04722.13 CRK21079.1 - 4.1e-83 277.6 0.0 4.7e-83 277.4 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein DsrH PF04077.12 CRK21079.1 - 0.15 12.2 0.0 8.7 6.6 0.0 2.3 2 0 0 2 2 2 0 DsrH like protein NAD_binding_1 PF00175.21 CRK21080.1 - 5.4e-32 110.7 0.0 9.4e-32 109.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 CRK21080.1 - 3.5e-09 37.0 0.0 7.6e-05 22.9 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_6 PF00970.24 CRK21080.1 - 6.7e-09 36.0 0.0 1.3e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain TFR_dimer PF04253.15 CRK21081.1 - 1.8e-24 86.1 0.0 3.4e-24 85.2 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 CRK21081.1 - 2.8e-19 69.6 0.0 4.2e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Nicastrin PF05450.15 CRK21081.1 - 0.036 13.5 0.0 0.065 12.7 0.0 1.3 1 0 0 1 1 1 0 Nicastrin DUF3046 PF11248.8 CRK21081.1 - 0.11 12.9 1.9 1.1 9.6 1.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3046) MFS_1 PF07690.16 CRK21082.1 - 1.4e-22 80.1 24.4 1.4e-22 80.1 24.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily IMPDH PF00478.25 CRK21083.1 - 1.7e-126 421.9 1.9 2e-126 421.6 1.9 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 CRK21083.1 - 7.6e-14 51.9 0.0 1.9e-05 25.0 0.0 2.5 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.18 CRK21083.1 - 6.3e-08 32.0 0.9 2.5e-06 26.8 0.6 2.3 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.15 CRK21083.1 - 2.1e-07 30.7 1.8 0.0032 16.9 1.4 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.21 CRK21083.1 - 0.00086 18.8 2.1 0.024 14.1 0.2 2.2 1 1 1 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.14 CRK21083.1 - 0.056 12.7 0.3 0.13 11.6 0.3 1.5 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG RasGAP PF00616.19 CRK21084.1 - 3.6e-51 173.8 0.1 1.5e-50 171.8 0.0 2.1 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 CRK21084.1 - 3.5e-48 163.2 2.0 3.5e-48 163.2 2.0 2.3 2 0 0 2 2 2 1 RasGAP C-terminus IQ PF00612.27 CRK21084.1 - 9.3e-12 43.7 42.1 0.021 14.6 0.7 13.1 14 0 0 14 14 14 5 IQ calmodulin-binding motif CH PF00307.31 CRK21084.1 - 6.4e-10 39.2 0.1 2.8e-09 37.1 0.0 2.1 2 0 0 2 2 2 1 Calponin homology (CH) domain DPM3 PF08285.11 CRK21085.1 - 0.13 12.4 1.4 0.38 11.0 1.3 1.8 1 1 0 1 1 1 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) CrgA PF06781.12 CRK21086.1 - 0.25 11.4 1.4 8.4 6.5 0.1 2.1 2 0 0 2 2 2 0 Cell division protein CrgA MBOAT PF03062.19 CRK21089.1 - 4.5e-47 161.1 12.4 4.5e-47 161.1 12.4 2.0 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Vps8 PF12816.7 CRK21090.1 - 5.2e-73 244.8 0.0 9.1e-73 244.0 0.0 1.4 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 CRK21090.1 - 0.00031 20.6 0.0 1 9.2 0.0 3.0 2 0 0 2 2 2 2 Region in Clathrin and VPS zf-RING_5 PF14634.6 CRK21090.1 - 0.012 15.6 0.1 0.031 14.2 0.1 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 CRK21090.1 - 0.016 15.2 0.1 0.036 14.1 0.1 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_11 PF17123.5 CRK21090.1 - 0.053 13.3 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 RING-like zinc finger zf-C3H2C3 PF17122.5 CRK21090.1 - 0.14 12.2 0.1 0.36 10.9 0.1 1.6 1 0 0 1 1 1 0 Zinc-finger zf-RING_2 PF13639.6 CRK21090.1 - 0.16 12.4 0.1 0.37 11.2 0.1 1.6 1 0 0 1 1 1 0 Ring finger domain DUF3752 PF12572.8 CRK21091.1 - 1.3e-20 74.5 2.0 1.3e-20 74.5 2.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) zf-RING_2 PF13639.6 CRK21092.1 - 7.2e-12 45.5 6.6 1.1e-11 44.9 6.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CRK21092.1 - 4e-08 33.0 6.1 6e-08 32.4 6.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CRK21092.1 - 7.6e-08 32.0 1.0 1.3e-07 31.3 1.0 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 CRK21092.1 - 2.2e-07 30.6 3.6 3.5e-07 30.0 3.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CRK21092.1 - 3.2e-06 27.3 9.4 1.6e-05 25.1 9.4 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 CRK21092.1 - 7.4e-06 25.8 3.6 1.1e-05 25.2 3.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 CRK21092.1 - 0.0012 18.9 1.6 0.0022 18.0 1.6 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 CRK21092.1 - 0.0029 17.4 2.6 0.0043 16.9 2.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CRK21092.1 - 0.0039 17.2 0.8 0.0039 17.2 0.8 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.6 CRK21092.1 - 0.026 14.3 6.4 0.043 13.6 6.3 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 CRK21092.1 - 0.18 12.0 2.1 0.4 10.9 2.1 1.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 CRK21092.1 - 0.22 11.4 5.0 0.43 10.5 5.0 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 PHD PF00628.29 CRK21092.1 - 0.23 11.4 6.0 0.39 10.6 6.0 1.4 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.8 CRK21092.1 - 0.45 10.7 3.0 1.1 9.5 3.0 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 CRK21092.1 - 0.89 9.2 5.1 1.6 8.4 5.1 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type OAD_gamma PF04277.13 CRK21092.1 - 0.98 10.1 0.0 0.98 10.1 0.0 4.3 4 2 0 4 4 1 0 Oxaloacetate decarboxylase, gamma chain zf-C3H2C3 PF17122.5 CRK21092.1 - 3.8 7.6 5.6 7.5 6.7 5.6 1.5 1 0 0 1 1 1 0 Zinc-finger Prok-RING_1 PF14446.6 CRK21092.1 - 9.6 6.2 9.0 0.22 11.5 1.5 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DUF3752 PF12572.8 CRK21093.1 - 3.9e-45 154.1 9.4 3.9e-45 154.1 9.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) zf-RING_2 PF13639.6 CRK21094.1 - 7.1e-12 45.5 6.6 1.1e-11 44.9 6.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CRK21094.1 - 4e-08 33.0 6.1 6e-08 32.4 6.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CRK21094.1 - 7.6e-08 32.0 1.0 1.3e-07 31.3 1.0 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 CRK21094.1 - 2.2e-07 30.6 3.6 3.5e-07 30.0 3.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CRK21094.1 - 3.2e-06 27.3 9.4 1.6e-05 25.1 9.4 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 CRK21094.1 - 7.3e-06 25.8 3.6 1.1e-05 25.2 3.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 CRK21094.1 - 0.0012 18.9 1.6 0.0022 18.0 1.6 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 CRK21094.1 - 0.0029 17.4 2.6 0.0043 16.9 2.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CRK21094.1 - 0.0039 17.2 0.8 0.0039 17.2 0.8 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.6 CRK21094.1 - 0.026 14.3 6.3 0.043 13.6 6.3 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 CRK21094.1 - 0.18 12.0 2.1 0.4 10.9 2.1 1.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 CRK21094.1 - 0.22 11.4 5.0 0.43 10.5 5.0 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 PHD PF00628.29 CRK21094.1 - 0.23 11.4 6.0 0.39 10.6 6.0 1.4 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.8 CRK21094.1 - 0.44 10.7 3.0 1.1 9.5 3.0 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 CRK21094.1 - 0.88 9.2 5.1 1.6 8.4 5.1 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type OAD_gamma PF04277.13 CRK21094.1 - 0.98 10.1 0.0 0.98 10.1 0.0 4.1 4 2 0 4 4 2 0 Oxaloacetate decarboxylase, gamma chain zf-C3H2C3 PF17122.5 CRK21094.1 - 3.8 7.6 5.6 7.5 6.7 5.6 1.5 1 0 0 1 1 1 0 Zinc-finger Prok-RING_1 PF14446.6 CRK21094.1 - 9.6 6.2 9.0 0.22 11.5 1.5 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Pro_isomerase PF00160.21 CRK21095.1 - 5.4e-81 270.5 9.5 3.2e-47 160.7 1.0 3.0 1 1 2 3 3 3 3 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF987 PF06174.11 CRK21095.1 - 9.5e-06 25.5 0.0 4.8 7.2 0.0 4.2 5 0 0 5 5 5 3 Protein of unknown function (DUF987) Chlam_OMP PF01308.17 CRK21095.1 - 0.00095 18.0 0.0 2.7 6.7 0.0 3.1 3 0 0 3 3 3 3 Chlamydia major outer membrane protein Thioredoxin_3 PF13192.6 CRK21095.1 - 0.17 11.9 0.0 0.36 10.9 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin domain FAM193_C PF15914.5 CRK21095.1 - 0.17 11.6 0.7 1.1e+02 2.7 0.0 3.1 3 0 0 3 3 3 0 FAM193 family C-terminal PepSY_2 PF13670.6 CRK21096.1 - 0.35 10.9 1.3 0.52 10.3 0.0 1.9 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Med3 PF11593.8 CRK21096.1 - 2.2 7.4 4.8 3.1 6.9 4.8 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal TEA PF01285.18 CRK21097.1 - 7.3e-27 93.3 0.3 1.5e-26 92.2 0.3 1.6 1 0 0 1 1 1 1 TEA/ATTS domain Integrin_b_cyt PF08725.11 CRK21097.1 - 0.22 11.2 0.6 0.82 9.4 0.1 2.2 2 0 0 2 2 2 0 Integrin beta cytoplasmic domain RRM_1 PF00076.22 CRK21098.1 - 2.2e-70 232.4 0.8 1.2e-16 60.2 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CRK21098.1 - 2.5e-05 24.3 0.1 5 7.3 0.0 4.6 4 0 0 4 4 4 2 RNA recognition motif RRM_3 PF08777.11 CRK21098.1 - 3.3e-05 23.9 5.4 0.21 11.6 0.0 5.4 5 1 0 6 6 6 1 RNA binding motif Nup35_RRM_2 PF14605.6 CRK21098.1 - 4.4e-05 23.4 0.0 0.0095 15.9 0.0 3.4 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 CRK21098.1 - 8e-05 22.4 0.0 1.1 9.2 0.0 4.5 5 0 0 5 5 5 2 Occluded RNA-recognition motif SET_assoc PF11767.8 CRK21098.1 - 0.00019 21.0 0.0 15 5.4 0.0 4.4 4 0 0 4 4 4 1 Histone lysine methyltransferase SET associated Limkain-b1 PF11608.8 CRK21098.1 - 0.0005 20.1 1.9 0.072 13.2 0.1 4.2 4 1 0 4 4 4 1 Limkain b1 RRM_Rrp7 PF17799.1 CRK21098.1 - 0.12 12.1 0.1 5.8 6.7 0.0 2.9 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain DUF1179 PF06678.11 CRK21098.1 - 3.1 7.8 6.1 2.3 8.2 3.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1179) Dynein_light PF01221.18 CRK21099.1 - 3.8e-39 132.9 0.8 5.1e-39 132.5 0.8 1.2 1 0 0 1 1 1 1 Dynein light chain type 1 Fer4_13 PF13370.6 CRK21105.1 - 3.2 8.3 4.7 21 5.7 0.0 3.9 3 2 1 4 4 4 0 4Fe-4S single cluster domain of Ferredoxin I RNA_pol_N PF01194.17 CRK21106.1 - 5.4e-31 106.7 0.9 6.3e-31 106.5 0.9 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.12 CRK21106.1 - 0.11 12.7 0.5 0.21 11.8 0.5 1.5 1 1 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) WD40 PF00400.32 CRK21107.1 - 1.5e-08 35.1 13.4 0.0016 19.2 0.2 6.2 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK21107.1 - 7e-06 26.3 0.2 0.042 14.1 0.1 4.3 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Peptidase_S9_N PF02897.15 CRK21107.1 - 0.069 11.9 0.0 1.2 7.8 0.0 2.5 2 0 0 2 2 2 0 Prolyl oligopeptidase, N-terminal beta-propeller domain zf-met2 PF12907.7 CRK21108.1 - 2.2e-15 56.5 6.4 3.4e-15 55.9 6.4 1.3 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.14 CRK21108.1 - 9.5e-10 39.2 9.5 1.8e-09 38.3 9.5 1.4 1 0 0 1 1 1 1 4F5 protein family Bap31 PF05529.12 CRK21109.1 - 1.1e-48 164.6 12.0 1.5e-48 164.1 12.0 1.2 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 CRK21109.1 - 2.1e-14 53.2 4.2 3.7e-14 52.5 4.2 1.4 1 0 0 1 1 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain TACC_C PF05010.14 CRK21109.1 - 0.0068 16.2 1.2 0.01 15.7 1.2 1.2 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Mod_r PF07200.13 CRK21109.1 - 0.011 15.8 0.5 0.019 15.0 0.5 1.3 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Wtap PF17098.5 CRK21109.1 - 0.018 15.0 0.7 0.035 14.0 0.7 1.5 1 0 0 1 1 1 0 WTAP/Mum2p family Spc7 PF08317.11 CRK21109.1 - 0.047 12.6 1.3 0.071 12.0 1.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein TolA_bind_tri PF16331.5 CRK21109.1 - 0.064 13.3 0.6 0.17 12.0 0.6 1.9 1 1 0 1 1 1 0 TolA binding protein trimerisation DUF192 PF02643.15 CRK21109.1 - 0.075 13.2 0.1 0.12 12.6 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized ACR, COG1430 Csm1_N PF18504.1 CRK21109.1 - 0.079 13.3 4.0 0.22 11.9 2.5 2.1 1 1 1 2 2 2 0 Csm1 N-terminal domain DivIC PF04977.15 CRK21109.1 - 0.08 12.7 4.3 0.53 10.1 0.4 3.1 3 1 1 4 4 4 0 Septum formation initiator UPF0242 PF06785.11 CRK21109.1 - 0.15 12.1 4.3 0.17 12.0 3.5 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus APG6_N PF17675.1 CRK21109.1 - 0.22 12.1 3.1 0.17 12.4 1.7 1.5 2 0 0 2 2 2 0 Apg6 coiled-coil region TMF_DNA_bd PF12329.8 CRK21109.1 - 1 9.4 6.5 1.6 8.8 5.8 1.7 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Peroxin-13_N PF04088.13 CRK21110.1 - 6.6e-51 172.4 0.0 1e-50 171.8 0.0 1.3 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.17 CRK21110.1 - 2.6e-08 33.4 0.0 4.8e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 CRK21110.1 - 1.3e-07 31.3 0.0 2.4e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CRK21110.1 - 3.8e-07 29.6 0.0 7.9e-07 28.6 0.0 1.6 1 1 0 1 1 1 1 SH3 domain SH3_3 PF08239.11 CRK21110.1 - 0.11 12.7 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial SH3 domain TraT PF05818.12 CRK21110.1 - 1.7 8.3 8.5 3.1 7.4 8.5 1.6 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein DUF2401 PF10287.9 CRK21111.1 - 3.5e-92 308.2 0.0 5.6e-92 307.5 0.0 1.3 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 CRK21111.1 - 4e-21 75.2 0.0 1.3e-20 73.6 0.0 1.9 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) XPG_N PF00752.17 CRK21112.1 - 3e-33 114.3 0.0 6.2e-33 113.3 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 CRK21112.1 - 2.2e-27 95.3 0.0 6.5e-27 93.7 0.0 1.9 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 CRK21112.1 - 0.052 14.2 0.0 0.21 12.2 0.0 2.0 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DUF1640 PF07798.11 CRK21118.1 - 2.1e-46 158.1 4.1 3.4e-46 157.5 4.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) PUF PF00806.19 CRK21121.1 - 6.9e-64 208.1 13.8 1.5e-08 33.8 0.1 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat SapB_2 PF03489.17 CRK21121.1 - 0.05 13.7 0.7 3.4 7.9 0.1 3.2 2 0 0 2 2 2 0 Saposin-like type B, region 2 MgtE_N PF03448.17 CRK21121.1 - 0.077 13.6 1.2 13 6.5 0.0 3.5 4 0 0 4 4 4 0 MgtE intracellular N domain PUF PF00806.19 CRK21122.1 - 1.6e-66 216.4 13.8 7e-09 34.9 0.1 8.2 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat MgtE_N PF03448.17 CRK21122.1 - 0.0044 17.6 1.2 4.9 7.8 0.0 3.7 4 0 0 4 4 4 1 MgtE intracellular N domain SapB_2 PF03489.17 CRK21122.1 - 0.053 13.6 2.9 1.6 8.9 0.1 3.3 3 0 0 3 3 3 0 Saposin-like type B, region 2 Ribosomal_L17 PF01196.19 CRK21122.1 - 0.09 13.7 0.2 6 7.8 0.0 3.0 1 1 1 2 2 2 0 Ribosomal protein L17 DUF1798 PF08807.10 CRK21122.1 - 0.16 12.1 2.4 1 9.6 0.1 3.0 3 0 0 3 3 3 0 Bacterial domain of unknown function (DUF1798) EphA2_TM PF14575.6 CRK21123.1 - 0.05 14.5 0.0 0.08 13.8 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain LapA_dom PF06305.11 CRK21123.1 - 0.23 11.3 0.9 0.43 10.4 0.9 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Sulfatase PF00884.23 CRK21124.1 - 2.4e-77 260.4 0.0 2.2e-40 139.0 0.0 2.4 2 0 0 2 2 2 2 Sulfatase SET PF00856.28 CRK21124.1 - 1.3e-17 64.7 0.2 6.3e-07 29.9 0.0 3.7 2 2 0 2 2 2 2 SET domain DUF229 PF02995.17 CRK21124.1 - 3.2e-08 32.6 0.0 0.0056 15.3 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF229) DUF4976 PF16347.5 CRK21124.1 - 3.4e-07 30.5 0.8 0.0082 16.4 0.1 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4976) Sulfatase_C PF14707.6 CRK21124.1 - 4.6e-05 24.1 0.0 0.19 12.5 0.0 2.6 2 0 0 2 2 2 2 C-terminal region of aryl-sulfatase SAF PF08666.12 CRK21124.1 - 0.054 14.1 7.1 19 6.0 0.1 4.7 6 0 0 6 6 6 0 SAF domain Phosphodiest PF01663.22 CRK21124.1 - 0.082 12.5 0.0 71 2.8 0.0 4.1 4 0 0 4 4 4 0 Type I phosphodiesterase / nucleotide pyrophosphatase CBM64 PF18666.1 CRK21124.1 - 0.12 12.4 0.0 26 5.0 0.0 2.5 2 0 0 2 2 2 0 Carbohydrate-binding module 64 Kinetochor_Ybp2 PF08568.10 CRK21125.1 - 1.3e-97 327.8 0.0 1.6e-97 327.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin Glyco_transf_28 PF03033.20 CRK21126.1 - 2e-18 66.8 0.1 1.1e-17 64.4 0.1 2.2 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 CRK21126.1 - 2.7e-07 29.8 0.0 6.5e-07 28.5 0.0 1.5 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.11 CRK21126.1 - 0.026 14.8 0.0 0.15 12.5 0.0 2.3 2 0 0 2 2 2 0 Autophagy-related protein C terminal domain TRIQK PF15168.6 CRK21126.1 - 0.055 13.4 2.1 1.9 8.4 2.1 2.9 3 0 0 3 3 3 0 Triple QxxK/R motif-containing protein family Glyco_tran_28_C PF04101.16 CRK21126.1 - 0.12 12.3 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain LRR_1 PF00560.33 CRK21127.1 - 0.02 15.4 11.0 22 6.1 0.0 6.8 8 0 0 8 8 8 0 Leucine Rich Repeat LRR_4 PF12799.7 CRK21127.1 - 0.04 14.4 5.5 3.1 8.4 0.1 4.3 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) DUF3678 PF12435.8 CRK21127.1 - 0.24 10.8 3.7 0.86 9.0 3.7 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) Chorion_2 PF03964.15 CRK21127.1 - 3 8.7 9.8 0.53 11.2 4.5 2.3 2 0 0 2 2 2 0 Chorion family 2 CAP59_mtransfer PF11735.8 CRK21129.1 - 2.4e-63 214.0 0.0 3.1e-63 213.7 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 FAD_binding_6 PF00970.24 CRK21130.1 - 8e-60 199.4 0.0 2e-28 98.6 0.0 2.6 2 0 0 2 2 2 2 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 CRK21130.1 - 8.7e-45 151.9 0.0 2.6e-27 95.6 0.0 2.2 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 CRK21130.1 - 1.2e-09 38.5 0.0 0.0058 16.8 0.0 3.2 3 0 0 3 3 3 2 Ferric reductase NAD binding domain DUF4176 PF13780.6 CRK21130.1 - 0.0053 16.8 0.1 6.3 6.9 0.0 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF4176) ABC2_membrane_2 PF12679.7 CRK21130.1 - 0.011 15.1 0.1 1.5 8.0 0.0 2.2 2 0 0 2 2 2 0 ABC-2 family transporter protein FRP PF18032.1 CRK21130.1 - 0.023 15.3 0.0 12 6.6 0.0 2.5 2 0 0 2 2 2 0 Photoprotection regulator fluorescence recovery protein DUF2187 PF09953.9 CRK21130.1 - 0.053 13.5 0.1 17 5.5 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2187) Phage_holin_5_2 PF16079.5 CRK21130.1 - 0.074 13.4 1.5 15 6.0 0.1 2.8 2 0 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V MFS_2 PF13347.6 CRK21130.1 - 0.11 11.0 0.4 3 6.3 0.1 2.1 2 0 0 2 2 2 0 MFS/sugar transport protein Sugar_tr PF00083.24 CRK21131.1 - 4.2e-72 243.4 10.8 7.9e-40 137.1 0.4 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CRK21131.1 - 8.8e-07 28.2 15.9 8.8e-07 28.2 15.9 2.3 1 1 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 CRK21132.1 - 7.1e-11 41.3 1.7 7.1e-11 41.3 1.7 3.0 3 0 0 3 3 3 1 MFS/sugar transport protein MFS_1 PF07690.16 CRK21132.1 - 7.6e-08 31.7 13.4 7.6e-08 31.7 13.4 3.7 2 1 1 3 3 3 2 Major Facilitator Superfamily PUCC PF03209.15 CRK21132.1 - 6.2e-05 22.2 2.0 6.2e-05 22.2 2.0 1.8 2 0 0 2 2 2 1 PUCC protein UPF0154 PF03672.13 CRK21132.1 - 0.0022 18.0 2.0 3.3 7.8 0.0 3.6 4 0 0 4 4 4 2 Uncharacterised protein family (UPF0154) RasGAP PF00616.19 CRK21132.1 - 0.014 15.1 0.2 6.1 6.5 0.0 2.3 2 0 0 2 2 2 0 GTPase-activator protein for Ras-like GTPase Antimicrobial_8 PF08103.11 CRK21132.1 - 0.047 13.8 1.0 2.8 8.3 0.2 2.7 2 0 0 2 2 2 0 Uperin family Fungal_trans_2 PF11951.8 CRK21133.1 - 1.5e-26 93.1 0.2 2.4e-14 52.9 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK21133.1 - 0.0035 17.4 17.4 0.0067 16.5 17.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MGC-24 PF05283.11 CRK21133.1 - 0.5 10.8 8.8 0.76 10.2 8.8 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Amino_oxidase PF01593.24 CRK21134.1 - 2.3e-50 172.2 0.1 2.8e-50 172.0 0.1 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CRK21134.1 - 2e-12 47.1 0.3 4.7e-12 46.0 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 CRK21134.1 - 9e-09 35.2 0.1 1e-07 31.7 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 CRK21134.1 - 1.9e-08 34.3 0.1 1.8e-06 27.8 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 CRK21134.1 - 8.2e-08 31.8 0.1 1.4e-07 31.1 0.1 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 CRK21134.1 - 4e-06 26.2 1.4 7.8e-06 25.2 1.4 1.4 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 CRK21134.1 - 7.2e-06 25.3 0.0 1.1e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 CRK21134.1 - 8.5e-06 25.2 0.0 2.6e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CRK21134.1 - 2.1e-05 23.4 0.0 0.00027 19.8 0.2 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 CRK21134.1 - 0.00015 21.2 0.2 0.14 11.3 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CRK21134.1 - 0.0024 18.4 0.3 0.01 16.4 0.4 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CRK21134.1 - 0.0068 15.5 0.8 0.01 15.0 0.3 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 CRK21134.1 - 0.091 12.0 0.1 0.16 11.2 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 CRK21134.1 - 0.15 11.3 2.3 0.13 11.5 1.1 1.5 2 0 0 2 2 2 0 FAD binding domain AA_permease_2 PF13520.6 CRK21135.1 - 1.9e-48 165.4 50.2 5.9e-48 163.7 50.2 1.6 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CRK21135.1 - 7.8e-23 80.8 48.2 6e-22 77.9 48.2 1.9 1 1 0 1 1 1 1 Amino acid permease Pox_EPC_I2-L1 PF12575.8 CRK21135.1 - 0.75 10.1 0.0 0.75 10.1 0.0 3.2 3 1 1 4 4 4 0 Poxvirus entry protein complex L1 and I2 Na_H_Exchanger PF00999.21 CRK21136.1 - 3.3e-69 233.5 35.1 4e-69 233.2 35.1 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Myb_DNA-bind_6 PF13921.6 CRK21137.1 - 1.8e-16 60.1 0.4 1.8e-16 60.1 0.4 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 CRK21137.1 - 2.9e-05 24.1 0.2 5.6e-05 23.2 0.2 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain MAPEG PF01124.18 CRK21139.1 - 8.1e-13 48.4 0.4 8.9e-13 48.3 0.4 1.0 1 0 0 1 1 1 1 MAPEG family Nnf1 PF03980.14 CRK21140.1 - 2.4e-32 111.6 0.3 4.4e-32 110.7 0.3 1.5 1 0 0 1 1 1 1 Nnf1 SlyX PF04102.12 CRK21140.1 - 1.2 9.8 6.1 4.6 7.9 1.9 2.9 2 1 0 2 2 2 0 SlyX PH_9 PF15410.6 CRK21141.1 - 1.1e-05 25.8 0.1 1.9e-05 25.0 0.1 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain DUF5372 PF17342.2 CRK21141.1 - 0.33 11.4 1.9 4.4 7.8 0.8 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5372) Tyrosinase PF00264.20 CRK21144.1 - 1.8e-23 84.0 0.3 2.2e-23 83.7 0.3 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase tRNA-synt_2b PF00587.25 CRK21150.1 - 5.6e-09 36.2 0.0 3.4e-07 30.4 0.0 2.4 2 1 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) GILT PF03227.16 CRK21180.1 - 0.0082 16.4 0.0 0.018 15.3 0.0 1.6 1 1 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Sin3_corepress PF08295.12 CRK21180.1 - 0.14 12.2 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 Sin3 family co-repressor VHS PF00790.19 CRK21181.1 - 0.0013 18.6 0.0 0.0014 18.4 0.0 1.0 1 0 0 1 1 1 1 VHS domain Glyco_hydro_43 PF04616.14 CRK21185.1 - 6.6e-09 35.5 1.4 8.1e-06 25.4 0.4 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.20 CRK21185.1 - 7.3e-06 25.8 2.3 4.7e-05 23.1 0.2 2.6 1 1 1 2 2 2 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_10 PF00331.20 CRK21186.1 - 1.4e-88 297.1 0.0 1.8e-88 296.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 NAD_binding_8 PF13450.6 CRK21186.1 - 9.6e-13 48.2 0.9 2.1e-12 47.1 0.3 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain CBM_1 PF00734.18 CRK21186.1 - 1.7e-08 34.2 15.3 1.7e-08 34.2 15.3 2.2 2 0 0 2 2 2 1 Fungal cellulose binding domain DAO PF01266.24 CRK21186.1 - 3.4e-06 26.9 0.4 1.1e-05 25.3 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CRK21186.1 - 2.8e-05 23.5 0.0 6.8e-05 22.2 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CRK21186.1 - 4.9e-05 22.6 0.1 9.7e-05 21.6 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 CRK21186.1 - 0.00013 21.4 0.0 0.0036 16.6 0.0 2.4 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 CRK21186.1 - 0.00051 20.1 0.0 0.0013 18.8 0.0 1.7 1 0 0 1 1 1 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 CRK21186.1 - 0.0014 17.7 0.0 0.0022 17.1 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 CRK21186.1 - 0.0044 15.8 0.1 0.007 15.1 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 CRK21186.1 - 0.0097 15.2 0.0 0.02 14.2 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 CRK21186.1 - 0.015 14.6 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.14 CRK21186.1 - 0.018 13.9 0.1 0.067 12.0 0.0 1.8 2 0 0 2 2 2 0 Tryptophan halogenase LolA_2 PF16584.5 CRK21186.1 - 0.027 14.3 0.2 1.3 8.8 0.2 2.4 1 1 0 1 1 1 0 Outer membrane lipoprotein carrier protein LolA Shikimate_DH PF01488.20 CRK21186.1 - 0.073 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 CRK21186.1 - 0.077 13.6 0.0 0.49 11.0 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CRK21186.1 - 0.1 12.0 0.1 0.28 10.5 0.0 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase MFS_1 PF07690.16 CRK21189.1 - 1.9e-33 115.9 25.9 1.9e-33 115.9 25.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily YrhC PF14143.6 CRK21189.1 - 1.9 8.7 4.2 2.8 8.1 0.4 3.0 2 0 0 2 2 2 0 YrhC-like protein DUF1189 PF06691.11 CRK21189.1 - 3.3 7.2 5.7 1.2 8.7 2.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1189) p450 PF00067.22 CRK21193.1 - 5.1e-55 187.1 0.0 6.8e-55 186.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NmrA PF05368.13 CRK21194.1 - 5.4e-20 72.0 0.1 7.3e-20 71.5 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 CRK21194.1 - 2.3e-10 40.7 0.3 4.2e-10 39.8 0.3 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 CRK21194.1 - 0.0032 17.9 0.1 0.0058 17.1 0.1 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 CRK21194.1 - 0.047 13.9 0.3 0.11 12.8 0.1 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Fungal_trans PF04082.18 CRK21195.1 - 0.00045 19.3 0.1 0.00066 18.8 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain SET PF00856.28 CRK21196.1 - 9.2e-13 48.9 0.0 6e-12 46.3 0.0 2.1 1 1 0 1 1 1 1 SET domain SAF PF08666.12 CRK21196.1 - 0.035 14.7 0.0 6.2 7.5 0.0 2.4 2 0 0 2 2 2 0 SAF domain D-ser_dehydrat PF14031.6 CRK21196.1 - 0.079 13.6 0.0 0.22 12.2 0.0 1.7 1 0 0 1 1 1 0 Putative serine dehydratase domain Tnp_P_element_C PF12596.8 CRK21197.1 - 0.0088 16.6 2.4 6.4 7.4 0.2 3.3 2 0 0 2 2 2 2 87kDa Transposase PBP_sp32 PF07222.12 CRK21197.1 - 0.097 12.1 17.3 0.18 11.3 7.3 2.8 2 0 0 2 2 2 0 Proacrosin binding protein sp32 CDK5_activator PF03261.15 CRK21197.1 - 3.5 7.1 8.8 6.7 6.1 3.1 2.4 2 0 0 2 2 2 0 Cyclin-dependent kinase 5 activator protein SET PF00856.28 CRK21199.1 - 9.1e-13 48.9 0.7 2.5e-11 44.3 0.0 3.3 2 2 0 2 2 2 1 SET domain D-ser_dehydrat PF14031.6 CRK21199.1 - 0.13 12.9 0.0 0.38 11.5 0.0 1.7 1 0 0 1 1 1 0 Putative serine dehydratase domain EBP PF05241.12 CRK21200.1 - 6.2e-54 182.2 6.3 7.7e-54 181.8 6.3 1.1 1 0 0 1 1 1 1 Emopamil binding protein MFS_1 PF07690.16 CRK21202.1 - 5e-32 111.2 30.4 8e-32 110.5 30.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 CRK21202.1 - 1.3e-20 73.4 7.8 1.7e-20 73.0 7.8 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) AzlD PF05437.12 CRK21202.1 - 0.11 12.7 8.9 0.048 13.9 3.7 2.6 2 0 0 2 2 2 0 Branched-chain amino acid transport protein (AzlD) Pro_CA PF00484.19 CRK21203.1 - 1.5e-50 171.5 0.1 2.3e-50 170.9 0.1 1.3 1 0 0 1 1 1 1 Carbonic anhydrase Peptidase_M6 PF05547.11 CRK21204.1 - 1.7e-08 33.3 0.1 1.2e-05 23.9 0.5 2.1 2 0 0 2 2 2 2 Immune inhibitor A peptidase M6 MFS_1 PF07690.16 CRK21205.1 - 1.8e-05 23.9 0.9 2.2e-05 23.6 0.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Peptidase_M6 PF05547.11 CRK21206.1 - 1.6e-05 23.5 0.8 2.5e-05 22.8 0.8 1.1 1 0 0 1 1 1 1 Immune inhibitor A peptidase M6 Babuvirus_MP PF07234.11 CRK21206.1 - 0.012 15.7 0.1 8.3 6.6 0.0 2.4 2 0 0 2 2 2 0 Movement and RNA silencing protein DUF1573 PF07610.11 CRK21206.1 - 0.17 11.9 0.1 27 4.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1573) He_PIG PF05345.12 CRK21206.1 - 0.17 12.1 0.4 35 4.7 0.1 2.9 2 0 0 2 2 2 0 Putative Ig domain MgsA_C PF12002.8 CRK21207.1 - 2.6e-60 203.2 0.1 4.3e-60 202.5 0.1 1.3 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 CRK21207.1 - 4.9e-21 74.9 0.6 1.1e-20 73.8 0.6 1.5 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 CRK21207.1 - 1.5e-12 48.1 0.1 2.7e-12 47.2 0.1 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CRK21207.1 - 2.1e-08 34.1 0.0 4.3e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 CRK21207.1 - 3.5e-06 26.8 0.0 0.00022 21.0 0.0 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.6 CRK21207.1 - 3.6e-06 27.5 1.4 0.0041 17.5 0.0 3.1 1 1 2 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 CRK21207.1 - 0.00019 21.4 0.0 0.00077 19.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 CRK21207.1 - 0.00064 19.2 0.0 0.29 10.5 0.0 2.2 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 CRK21207.1 - 0.00086 19.6 0.2 0.005 17.1 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CRK21207.1 - 0.0012 18.9 0.0 0.0019 18.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 CRK21207.1 - 0.0026 17.0 0.0 0.004 16.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TIP49 PF06068.13 CRK21207.1 - 0.0083 15.4 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_19 PF13245.6 CRK21207.1 - 0.014 15.7 0.3 0.2 12.0 0.2 2.2 1 1 1 2 2 2 0 AAA domain CPT PF07931.12 CRK21207.1 - 0.031 14.1 0.0 0.065 13.1 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein ResIII PF04851.15 CRK21207.1 - 0.031 14.3 0.5 1.1 9.2 0.0 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_24 PF13479.6 CRK21207.1 - 0.043 13.5 0.0 0.069 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CRK21207.1 - 0.047 13.4 0.2 0.14 11.8 0.2 1.8 1 1 0 1 1 1 0 AAA domain TRAF6_Z2 PF18048.1 CRK21207.1 - 0.05 13.7 0.3 0.11 12.6 0.3 1.6 1 0 0 1 1 1 0 TNF receptor-associated factor 6 zinc finger 2 AAA_28 PF13521.6 CRK21207.1 - 0.098 12.9 0.9 0.31 11.2 0.9 1.9 1 1 0 1 1 1 0 AAA domain SKI PF01202.22 CRK21207.1 - 0.099 12.8 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Shikimate kinase TniB PF05621.11 CRK21207.1 - 0.11 11.8 0.0 0.28 10.6 0.0 1.6 1 1 0 1 1 1 0 Bacterial TniB protein AAA_3 PF07726.11 CRK21207.1 - 0.15 12.0 0.0 0.54 10.1 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.6 CRK21207.1 - 0.19 11.9 0.0 0.36 11.0 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Fe-S_biosyn PF01521.20 CRK21208.1 - 5e-14 52.4 0.0 7.9e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis MgsA_C PF12002.8 CRK21210.1 - 3.6e-60 202.7 0.1 6e-60 202.0 0.1 1.3 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 CRK21210.1 - 4.8e-21 74.9 0.6 1.1e-20 73.8 0.6 1.5 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 CRK21210.1 - 1.4e-12 48.2 0.1 2.7e-12 47.2 0.1 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CRK21210.1 - 3.9e-08 33.2 0.0 8e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 CRK21210.1 - 3.5e-06 26.8 0.0 0.00022 21.0 0.0 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.6 CRK21210.1 - 5e-06 27.0 2.1 0.0043 17.4 0.1 3.1 1 1 1 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 CRK21210.1 - 0.00014 21.8 0.1 0.00074 19.5 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 CRK21210.1 - 0.00063 19.2 0.0 0.28 10.5 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 CRK21210.1 - 0.0008 19.7 0.2 0.0056 17.0 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CRK21210.1 - 0.0015 18.6 0.0 0.0022 18.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 CRK21210.1 - 0.0029 16.8 0.0 0.0045 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TIP49 PF06068.13 CRK21210.1 - 0.012 14.8 0.0 0.019 14.1 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_19 PF13245.6 CRK21210.1 - 0.014 15.7 0.3 0.2 12.0 0.2 2.3 1 1 1 2 2 2 0 AAA domain CPT PF07931.12 CRK21210.1 - 0.032 14.1 0.0 0.067 13.0 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein ResIII PF04851.15 CRK21210.1 - 0.033 14.2 0.5 1.2 9.2 0.0 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_30 PF13604.6 CRK21210.1 - 0.041 13.6 0.3 0.13 12.0 0.3 1.7 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CRK21210.1 - 0.043 13.5 0.0 0.069 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain TRAF6_Z2 PF18048.1 CRK21210.1 - 0.051 13.7 0.3 0.11 12.6 0.3 1.6 1 0 0 1 1 1 0 TNF receptor-associated factor 6 zinc finger 2 AAA_28 PF13521.6 CRK21210.1 - 0.087 13.1 0.9 0.31 11.2 0.9 2.0 1 1 0 1 1 1 0 AAA domain SKI PF01202.22 CRK21210.1 - 0.099 12.8 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Shikimate kinase TniB PF05621.11 CRK21210.1 - 0.12 11.8 0.0 0.29 10.5 0.0 1.6 1 1 0 1 1 1 0 Bacterial TniB protein AAA_3 PF07726.11 CRK21210.1 - 0.16 11.9 0.0 0.54 10.1 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.6 CRK21210.1 - 0.19 11.8 0.0 0.37 10.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF1741 PF08427.10 CRK21211.1 - 7.9e-26 91.1 0.0 1.4e-25 90.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) DUF423 PF04241.15 CRK21212.1 - 0.018 15.2 1.0 0.058 13.6 1.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF423) Cytochrom_B_C PF00032.17 CRK21212.1 - 0.038 14.3 2.2 0.077 13.3 0.1 2.4 1 1 1 2 2 2 0 Cytochrome b(C-terminal)/b6/petD PP2C_2 PF13672.6 CRK21212.1 - 0.21 11.2 0.3 0.31 10.7 0.3 1.2 1 0 0 1 1 1 0 Protein phosphatase 2C DUF4682 PF15733.5 CRK21213.1 - 0.022 15.3 4.1 1.4 9.5 0.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4682) Utp12 PF04003.12 CRK21214.1 - 3e-22 79.0 0.3 6.8e-22 77.8 0.1 1.7 2 0 0 2 2 2 1 Dip2/Utp12 Family SDA1 PF05285.12 CRK21214.1 - 0.097 12.1 33.0 0.068 12.6 5.8 2.2 2 0 0 2 2 2 0 SDA1 Nop14 PF04147.12 CRK21214.1 - 1 7.5 29.2 0.56 8.3 1.3 2.2 2 0 0 2 2 2 0 Nop14-like family Bromodomain PF00439.25 CRK21215.1 - 2.4e-33 114.0 0.0 8.4e-19 67.4 0.0 2.5 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 CRK21215.1 - 1.3e-12 47.7 1.3 1.3e-12 47.7 1.3 2.0 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation DUF2555 PF10742.9 CRK21215.1 - 0.11 12.3 0.5 0.29 11.0 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2555) cobW PF02492.19 CRK21217.1 - 9.2e-30 103.5 0.0 1e-29 103.4 0.0 1.0 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 CRK21217.1 - 3.4e-05 23.7 0.0 4.5e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.6 CRK21217.1 - 0.0026 18.0 0.0 0.0028 18.0 0.0 1.3 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 CRK21217.1 - 0.0027 17.5 0.0 0.0028 17.5 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 CRK21217.1 - 0.0087 15.3 0.0 0.01 15.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 CRK21217.1 - 0.0088 16.0 0.1 0.018 15.0 0.0 1.5 2 0 0 2 2 2 1 NTPase TrwB_AAD_bind PF10412.9 CRK21217.1 - 0.018 14.0 0.0 0.023 13.6 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF463 PF04317.12 CRK21217.1 - 0.02 13.9 0.0 0.024 13.6 0.0 1.1 1 0 0 1 1 1 0 YcjX-like family, DUF463 AAA_16 PF13191.6 CRK21217.1 - 0.028 14.8 0.0 0.03 14.7 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 CRK21217.1 - 0.037 13.8 0.1 0.057 13.2 0.1 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.6 CRK21217.1 - 0.05 13.6 0.0 0.062 13.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 CRK21217.1 - 0.051 13.2 0.0 0.062 12.9 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ATPase_2 PF01637.18 CRK21217.1 - 0.077 12.9 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_18 PF13238.6 CRK21217.1 - 0.081 13.5 0.3 0.084 13.4 0.3 1.3 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 CRK21217.1 - 0.098 12.4 0.0 0.12 12.1 0.0 1.2 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 CRK21217.1 - 0.11 12.5 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 CRK21217.1 - 0.17 12.0 0.0 0.19 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 CRK21217.1 - 0.22 10.6 1.1 0.36 9.8 1.1 1.6 1 1 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.6 CRK21217.1 - 0.54 10.7 1.9 0.8 10.2 1.9 1.2 1 0 0 1 1 1 0 AAA domain EMC3_TMCO1 PF01956.16 CRK21251.1 - 7.4e-11 42.1 0.6 7.9e-11 42.0 0.6 1.0 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like ERAP1_C PF11838.8 CRK21256.1 - 0.00014 21.6 0.1 0.00033 20.3 0.0 1.7 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_C2 PF00648.21 CRK21257.1 - 1.4e-59 201.6 0.2 6.4e-58 196.1 0.2 2.2 1 1 0 1 1 1 1 Calpain family cysteine protease LigT_PEase PF02834.16 CRK21259.1 - 0.077 13.2 0.5 0.18 12.0 0.5 1.6 1 0 0 1 1 1 0 LigT like Phosphoesterase tRNA-synt_1g PF09334.11 CRK21260.1 - 1.5e-136 455.3 2.9 2.6e-129 431.4 0.6 3.3 1 1 1 2 2 2 2 tRNA synthetases class I (M) ADH_N PF08240.12 CRK21260.1 - 7.4e-25 87.0 3.8 1.4e-24 86.0 3.8 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CRK21260.1 - 3.4e-14 53.0 0.0 9.6e-14 51.5 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase tRNA-synt_1 PF00133.22 CRK21260.1 - 2.2e-05 22.9 0.1 0.0037 15.6 0.0 3.3 3 1 1 4 4 4 1 tRNA synthetases class I (I, L, M and V) 2-Hacid_dh_C PF02826.19 CRK21260.1 - 0.00017 21.0 0.1 0.00036 19.9 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 CRK21260.1 - 0.048 13.3 0.0 0.091 12.4 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.21 CRK21260.1 - 0.076 12.3 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Anticodon_1 PF08264.13 CRK21260.1 - 0.1 12.5 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA WD40 PF00400.32 CRK21261.1 - 9.3e-28 95.9 16.7 7.4e-06 26.6 0.1 8.0 9 0 0 9 9 9 6 WD domain, G-beta repeat F-box-like PF12937.7 CRK21261.1 - 1.2e-10 41.1 0.1 2.3e-10 40.2 0.1 1.5 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 CRK21261.1 - 1.4e-06 28.5 0.2 0.0035 17.6 0.0 4.3 2 1 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CRK21261.1 - 0.00015 20.6 0.1 1.8 7.1 0.0 3.2 2 1 1 3 3 3 2 Nucleoporin Nup120/160 F-box PF00646.33 CRK21261.1 - 0.0049 16.7 0.0 0.0094 15.8 0.0 1.5 1 0 0 1 1 1 1 F-box domain Cytochrom_D1 PF02239.16 CRK21261.1 - 0.039 12.5 0.0 0.077 11.5 0.0 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain Frtz PF11768.8 CRK21261.1 - 0.045 12.1 0.1 0.13 10.5 0.1 1.7 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz STE PF02200.16 CRK21261.1 - 0.15 12.5 0.1 3.3 8.2 0.0 2.4 2 0 0 2 2 2 0 STE like transcription factor Pectate_lyase_3 PF12708.7 CRK21262.1 - 9.6e-91 303.4 12.4 1.9e-81 273.0 4.7 2.9 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 CRK21262.1 - 1.1e-06 28.2 1.2 0.042 13.5 0.1 2.6 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase TSP_C PF05735.12 CRK21262.1 - 0.0093 15.9 0.4 0.025 14.5 0.4 1.6 1 0 0 1 1 1 1 Thrombospondin C-terminal region Scs3p PF10261.9 CRK21263.1 - 7.9e-75 251.5 4.3 1e-74 251.2 4.3 1.1 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM Cation_efflux PF01545.21 CRK21263.1 - 0.00018 21.3 0.1 0.015 15.0 0.3 2.4 2 0 0 2 2 2 2 Cation efflux family ATP_transf PF09830.9 CRK21265.1 - 8.7e-20 70.6 0.0 1.6e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 ATP adenylyltransferase Man-6-P_recep PF02157.15 CRK21265.1 - 1.6e-15 56.9 0.0 7.7e-15 54.7 0.0 1.9 1 1 1 2 2 2 1 Mannose-6-phosphate receptor ATG27 PF09451.10 CRK21265.1 - 2.7e-11 43.8 0.0 7.7e-11 42.3 0.0 1.8 1 1 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 CRK21265.1 - 1.4e-05 25.2 0.1 0.0047 17.0 0.0 2.4 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat ERG4_ERG24 PF01222.17 CRK21266.1 - 1.5e-164 547.8 4.0 1.8e-164 547.6 4.0 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 CRK21266.1 - 0.00019 21.0 1.7 0.00028 20.5 0.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) Glyco_hydro_3_C PF01915.22 CRK21267.1 - 3.5e-50 170.8 0.0 9.3e-49 166.2 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 CRK21267.1 - 1.2e-29 103.7 0.0 2e-29 103.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 CRK21267.1 - 6.9e-19 67.7 0.0 1.6e-18 66.6 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain PALP PF00291.25 CRK21268.1 - 2.3e-58 197.9 0.2 3.2e-58 197.5 0.2 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Aldo_ket_red PF00248.21 CRK21269.1 - 1.6e-52 178.6 0.2 4.6e-28 98.2 0.0 4.0 2 1 1 3 3 3 2 Aldo/keto reductase family AGA2 PF17366.2 CRK21269.1 - 0.037 13.7 0.2 13 5.6 0.0 2.7 2 0 0 2 2 2 0 A-agglutinin-binding subunit Aga2 DUF1120 PF06551.12 CRK21269.1 - 0.045 13.9 0.0 17 5.6 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1120) DUF3335 PF11814.8 CRK21269.1 - 0.055 12.9 0.0 14 5.1 0.0 2.6 2 0 0 2 2 2 0 Peptidase_C39 like family CDC24 PF06395.11 CRK21269.1 - 0.065 13.5 0.0 7.3 6.9 0.0 2.5 2 0 0 2 2 2 0 CDC24 Calponin HET PF06985.11 CRK21270.1 - 5e-19 69.1 2.4 1.3e-18 67.7 2.4 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RPA43_OB PF17875.1 CRK21270.1 - 1.7 9.3 4.1 1.4 9.6 2.2 1.7 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I tRNA_bind_3 PF17176.4 CRK21271.1 - 0.11 12.8 0.3 0.2 11.9 0.3 1.4 1 1 0 1 1 1 0 tRNA-binding domain zf-C3HC4_3 PF13920.6 CRK21272.1 - 7.8e-09 35.3 4.5 7.8e-09 35.3 4.5 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CRK21272.1 - 1.6e-08 34.8 4.3 3.9e-08 33.5 4.3 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 CRK21272.1 - 1.5e-07 31.3 3.5 4e-07 29.9 3.5 1.8 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 CRK21272.1 - 1.9e-07 30.8 2.5 8.8e-07 28.7 2.5 2.2 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CRK21272.1 - 8.8e-07 28.8 4.0 8.8e-07 28.8 4.0 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CRK21272.1 - 9.7e-07 28.6 2.6 2.4e-06 27.3 2.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CRK21272.1 - 1.8e-06 27.7 1.4 1.8e-06 27.7 1.4 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CRK21272.1 - 3.5e-05 23.9 3.3 9.3e-05 22.5 3.3 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 CRK21272.1 - 0.17 12.1 1.7 0.45 10.7 1.7 1.8 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_14 PF17978.1 CRK21272.1 - 0.18 12.3 1.3 1.9 8.9 0.3 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain GATase PF00117.28 CRK21273.1 - 2.3e-06 27.5 0.0 3.1e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Antimicrobial_9 PF08104.11 CRK21273.1 - 0.36 10.9 2.8 0.78 9.8 2.8 1.6 1 0 0 1 1 1 0 Ponericin L family Methyltransf_25 PF13649.6 CRK21274.1 - 2e-22 79.7 0.0 3.5e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CRK21274.1 - 3.1e-19 69.4 0.0 5.2e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK21274.1 - 1e-18 67.6 0.0 1.3e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK21274.1 - 1e-11 45.5 0.0 1.7e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CRK21274.1 - 2.5e-11 43.4 0.0 3.5e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 CRK21274.1 - 6.1e-10 39.2 0.0 8e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CRK21274.1 - 3.7e-07 29.7 0.0 5e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.19 CRK21274.1 - 5.7e-07 29.5 0.0 8.7e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 CRK21274.1 - 3.6e-06 26.6 0.0 5.4e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.12 CRK21274.1 - 0.00031 20.4 0.0 0.00044 19.9 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_4 PF02390.17 CRK21274.1 - 0.00037 20.0 0.0 0.00072 19.1 0.0 1.5 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_2 PF00891.18 CRK21274.1 - 0.0086 15.4 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain FtsJ PF01728.19 CRK21274.1 - 0.024 14.8 0.0 0.069 13.3 0.0 1.7 1 1 0 1 1 1 0 FtsJ-like methyltransferase CheR PF01739.18 CRK21274.1 - 0.038 13.5 0.0 0.94 8.9 0.0 2.1 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltr_RsmB-F PF01189.17 CRK21274.1 - 0.13 11.8 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Methyltransf_18 PF12847.7 CRK21274.1 - 0.18 11.7 0.0 0.27 11.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 CRK21274.1 - 0.22 11.5 0.0 0.34 10.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Fungal_trans_2 PF11951.8 CRK21275.1 - 1.9e-37 129.0 1.8 5.2e-37 127.6 1.8 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK21275.1 - 0.0064 16.6 2.2 0.011 15.8 2.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_7 PF03441.14 CRK21276.1 - 7.3e-76 254.2 0.4 1.4e-75 253.3 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase Velvet PF11754.8 CRK21276.1 - 3e-52 178.0 0.9 3.9e-34 118.7 0.1 4.2 4 1 1 5 5 5 2 Velvet factor DNA_photolyase PF00875.18 CRK21276.1 - 4.1e-34 118.0 0.0 2.2e-33 115.6 0.0 2.2 2 0 0 2 2 2 1 DNA photolyase FF PF01846.19 CRK21276.1 - 0.15 12.2 0.1 0.35 11.1 0.1 1.6 1 0 0 1 1 1 0 FF domain AMP-binding PF00501.28 CRK21277.1 - 1.7e-75 254.3 0.0 2.6e-75 253.6 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 CRK21277.1 - 1.1e-58 198.4 0.0 2.1e-58 197.5 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein adh_short PF00106.25 CRK21277.1 - 3.6e-50 170.1 5.4 7.5e-50 169.1 4.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK21277.1 - 3.4e-37 128.3 2.1 7.6e-37 127.1 2.1 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK21277.1 - 4.4e-18 65.8 3.8 7.2e-14 52.1 1.9 2.4 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 CRK21277.1 - 1.5e-13 50.8 0.1 1.4e-09 37.8 0.0 3.0 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 CRK21277.1 - 6.8e-10 39.2 0.0 1.5e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 CRK21277.1 - 2.1e-05 23.7 0.3 0.0022 17.0 0.0 2.9 3 0 0 3 3 3 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 CRK21277.1 - 0.00015 21.0 4.1 0.00086 18.5 0.1 3.3 3 1 0 3 3 3 1 RmlD substrate binding domain AMP-binding_C PF13193.6 CRK21277.1 - 0.00019 22.4 0.0 0.0011 19.9 0.0 2.4 2 0 0 2 2 1 1 AMP-binding enzyme C-terminal domain NAD_binding_10 PF13460.6 CRK21277.1 - 0.00019 21.4 0.9 0.0022 17.9 0.6 2.4 2 0 0 2 2 2 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 CRK21277.1 - 0.00071 18.8 2.3 0.33 10.1 0.1 3.1 3 1 0 3 3 3 2 Polysaccharide biosynthesis protein THF_DHG_CYH_C PF02882.19 CRK21277.1 - 0.0025 17.2 1.1 0.0068 15.7 1.1 1.8 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ApbA PF02558.16 CRK21277.1 - 0.072 12.7 0.2 0.16 11.6 0.2 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NmrA PF05368.13 CRK21277.1 - 0.59 9.6 3.2 13 5.2 0.0 2.5 2 0 0 2 2 2 0 NmrA-like family Pyridox_ox_2 PF12900.7 CRK21278.1 - 0.029 14.4 0.1 0.062 13.3 0.1 1.5 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Peptidase_M22 PF00814.25 CRK21282.1 - 4.3e-43 148.0 0.0 4.6e-43 147.9 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family GDI PF00996.18 CRK21285.1 - 1.3e-62 211.8 0.0 1.4e-62 211.6 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor CPSF_A PF03178.15 CRK21304.1 - 7.7e-33 114.2 0.0 9.2e-33 113.9 0.0 1.1 1 0 0 1 1 1 1 CPSF A subunit region Smg4_UPF3 PF03467.15 CRK21319.1 - 0.15 12.1 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Smg-4/UPF3 family Ank_2 PF12796.7 CRK21321.1 - 8.5e-28 96.8 10.7 3e-14 53.4 1.7 4.4 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CRK21321.1 - 4.2e-22 78.2 2.6 1.4e-06 28.8 0.0 5.5 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 CRK21321.1 - 1.6e-15 56.8 11.0 0.0099 16.3 0.2 7.0 6 1 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 CRK21321.1 - 5.1e-11 41.8 0.2 3 8.7 0.0 7.0 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 CRK21321.1 - 7.3e-10 38.9 6.0 0.11 12.8 0.2 6.0 2 1 4 6 6 6 4 Ankyrin repeats (many copies) NACHT PF05729.12 CRK21321.1 - 2.2e-09 37.5 0.0 6.4e-09 35.9 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 CRK21321.1 - 5.7e-07 30.1 2.3 7.7e-06 26.4 0.0 3.5 4 0 0 4 4 4 1 AAA ATPase domain NB-ARC PF00931.22 CRK21321.1 - 0.035 13.3 0.0 0.092 11.9 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain Goodbye PF17109.5 CRK21321.1 - 0.055 13.9 3.4 0.06 13.8 0.0 2.8 3 0 0 3 3 3 0 fungal STAND N-terminal Goodbye domain AAA_22 PF13401.6 CRK21321.1 - 0.071 13.4 0.3 0.37 11.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain NFRKB_winged PF14465.6 CRK21321.1 - 0.076 13.2 0.5 0.43 10.8 0.0 2.5 2 0 0 2 2 2 0 NFRKB Winged Helix-like KAP_NTPase PF07693.14 CRK21321.1 - 0.28 10.4 1.8 0.58 9.3 0.0 2.1 2 1 0 2 2 2 0 KAP family P-loop domain AAA PF00004.29 CRK21321.1 - 0.32 11.4 1.2 2.1 8.8 0.0 2.8 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Transferase PF02458.15 CRK21322.1 - 2.5e-12 46.2 0.0 5.3e-09 35.2 0.0 3.0 2 1 0 2 2 2 2 Transferase family NB-ARC PF00931.22 CRK21323.1 - 1.1e-08 34.6 0.0 1.8e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 CRK21323.1 - 3.3e-07 30.8 0.0 7.4e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain DUF676 PF05057.14 CRK21323.1 - 0.078 12.5 0.1 0.21 11.1 0.1 1.6 1 1 0 1 1 1 0 Putative serine esterase (DUF676) ATPase_2 PF01637.18 CRK21323.1 - 0.087 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea PGAP1 PF07819.13 CRK21323.1 - 0.088 12.5 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Syntaxin-6_N PF09177.11 CRK21323.1 - 0.15 12.6 0.0 0.55 10.8 0.0 1.9 1 0 0 1 1 1 0 Syntaxin 6, N-terminal BcrAD_BadFG PF01869.20 CRK21324.1 - 9.9e-06 25.2 0.0 1.8e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family SIS PF01380.22 CRK21324.1 - 1.6e-05 24.8 0.1 0.00027 20.8 0.0 2.4 2 0 0 2 2 2 1 SIS domain SIS_2 PF13580.6 CRK21324.1 - 0.0003 20.8 0.2 0.00073 19.6 0.2 1.7 1 0 0 1 1 1 1 SIS domain SRP19 PF01922.17 CRK21324.1 - 0.13 13.2 0.1 0.27 12.2 0.1 1.5 1 0 0 1 1 1 0 SRP19 protein MFS_1 PF07690.16 CRK21325.1 - 6.1e-14 51.7 31.9 6.1e-14 51.7 31.9 2.3 1 1 1 3 3 3 1 Major Facilitator Superfamily UNC-93 PF05978.16 CRK21325.1 - 5.5e-09 35.9 3.5 5.5e-09 35.9 3.5 3.3 1 1 2 3 3 3 1 Ion channel regulatory protein UNC-93 Glyco_hydro_56 PF01630.18 CRK21326.1 - 0.014 14.4 0.0 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 Hyaluronidase Fungal_trans PF04082.18 CRK21327.1 - 1.3e-12 47.3 0.0 2e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK21327.1 - 4.3e-12 45.9 28.0 7.4e-07 29.2 11.1 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain PI-PLC-X PF00388.19 CRK21329.1 - 4.1e-47 159.4 0.0 6e-47 158.9 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 CRK21329.1 - 4.1e-39 133.5 0.0 6.5e-39 132.8 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 CRK21329.1 - 0.051 13.9 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 C2 domain DUF4701 PF15773.5 CRK21329.1 - 0.11 11.5 2.5 0.18 10.8 2.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4701) YL1 PF05764.13 CRK21329.1 - 0.12 12.5 1.5 0.67 10.0 1.9 1.9 2 0 0 2 2 2 0 YL1 nuclear protein Cwf_Cwc_15 PF04889.12 CRK21329.1 - 0.2 11.4 3.4 0.34 10.6 3.4 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PBP1_TM PF14812.6 CRK21329.1 - 5.7 7.4 6.6 6 7.3 3.4 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3176 PF11374.8 CRK21330.1 - 1.1e-31 109.2 0.8 3e-31 107.8 0.8 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) DUF4328 PF14219.6 CRK21330.1 - 0.57 9.7 6.6 0.075 12.6 2.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4328) MIG-14_Wnt-bd PF06664.12 CRK21330.1 - 3.5 6.8 7.9 4 6.6 3.3 2.2 2 0 0 2 2 2 0 Wnt-binding factor required for Wnt secretion Acetyltransf_1 PF00583.25 CRK21332.1 - 5.1e-05 23.5 0.0 0.00016 21.9 0.0 1.8 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CRK21332.1 - 0.0038 17.6 0.0 0.0067 16.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CRK21332.1 - 0.12 12.3 0.0 0.52 10.3 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain SurE PF01975.17 CRK21334.1 - 1.4e-24 87.0 0.1 2.1e-24 86.4 0.1 1.2 1 0 0 1 1 1 1 Survival protein SurE MFS_1 PF07690.16 CRK21336.1 - 5.9e-34 117.5 29.5 5.9e-34 117.5 29.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK21336.1 - 4.8e-13 48.8 9.7 4.8e-13 48.8 9.7 2.5 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 CRK21336.1 - 7.2e-07 28.0 1.8 7.2e-07 28.0 1.8 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) BT1 PF03092.16 CRK21336.1 - 0.0042 15.4 0.6 0.0083 14.4 0.6 1.6 1 0 0 1 1 1 1 BT1 family Glyco_hydro_17 PF00332.18 CRK21337.1 - 6.7e-06 25.9 0.8 1.2e-05 25.1 0.7 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 Plasmodium_Vir PF05795.11 CRK21337.1 - 0.31 10.4 0.7 0.43 9.9 0.7 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Glyco_hydro_17 PF00332.18 CRK21338.1 - 8.4e-07 28.9 0.7 1.7e-06 27.9 0.7 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Zn_clus PF00172.18 CRK21339.1 - 1.3e-07 31.6 7.8 2.4e-07 30.8 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 CRK21339.1 - 0.024 13.4 0.4 0.054 12.3 0.1 1.6 2 0 0 2 2 2 0 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK21340.1 - 8.2e-09 35.4 11.1 1.3e-08 34.8 11.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 CRK21340.1 - 4.9e-05 22.5 0.1 9.2e-05 21.6 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain HET PF06985.11 CRK21341.1 - 3.2e-05 24.3 0.9 0.0033 17.8 0.9 2.4 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) p450 PF00067.22 CRK21342.1 - 9.1e-44 150.0 0.0 1.3e-43 149.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_7 PF00840.20 CRK21343.1 - 7.3e-140 466.5 0.3 9.1e-140 466.2 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 LPAM_2 PF13627.6 CRK21343.1 - 0.029 14.2 1.2 0.064 13.1 1.2 1.6 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site DHR10 PF18595.1 CRK21344.1 - 0.0068 16.5 0.3 0.014 15.4 0.3 1.4 1 0 0 1 1 1 1 Designed helical repeat protein 10 domain Metallophos PF00149.28 CRK21347.1 - 8.5e-10 39.5 0.1 1.1e-09 39.2 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase YmdB PF13277.6 CRK21347.1 - 0.001 18.5 0.0 0.0013 18.1 0.0 1.1 1 0 0 1 1 1 1 YmdB-like protein ATP-synt_ab_C PF00306.27 CRK21351.1 - 1.8e-31 109.1 0.1 2.3e-31 108.8 0.1 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab PF00006.25 CRK21351.1 - 7.1e-30 104.3 0.0 1e-29 103.8 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain DUF3188 PF11384.8 CRK21358.1 - 7.9 6.3 7.1 6.5 6.5 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) DUF202 PF02656.15 CRK21358.1 - 9.3 6.8 8.4 20 5.7 7.3 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF202) FMN_bind_2 PF04299.12 CRK21387.1 - 2e-28 99.2 0.2 2.1e-28 99.2 0.2 1.0 1 0 0 1 1 1 1 Putative FMN-binding domain SOG2 PF10428.9 CRK21391.1 - 2.5e-73 248.0 0.0 1.2e-49 169.9 0.0 3.7 3 1 1 4 4 4 2 RAM signalling pathway protein Pyr_redox_2 PF07992.14 CRK21392.1 - 1.1e-53 182.5 0.2 1.1e-49 169.3 0.1 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CRK21392.1 - 1.8e-18 66.9 0.0 4.9e-18 65.5 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CRK21392.1 - 1e-08 34.8 0.0 1.5e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CRK21392.1 - 2.6e-06 26.8 0.0 6.1e-06 25.6 0.0 1.5 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_dim PF02852.22 CRK21392.1 - 0.00073 19.8 0.2 0.0045 17.2 0.1 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Adhesin_P1_N PF18652.1 CRK21392.1 - 0.066 13.2 0.0 21 5.2 0.0 2.7 2 0 0 2 2 2 0 Adhesin P1 N-terminal domain MOSP_N PF02707.16 CRK21392.1 - 0.077 12.8 0.0 0.23 11.2 0.0 1.8 1 1 0 1 1 1 0 Major Outer Sheath Protein N-terminal region Vault_4 PF17796.1 CRK21392.1 - 0.14 12.3 0.1 27 4.9 0.0 2.4 2 0 0 2 2 2 0 Major Vault Protein repeat domain Myosin_N PF02736.19 CRK21392.1 - 0.18 11.7 0.2 33 4.4 0.0 2.6 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain Papilloma_E5A PF05776.12 CRK21394.1 - 2.1 8.7 10.5 2.3 8.6 0.3 3.0 2 1 0 2 2 2 0 Papillomavirus E5A protein HMA PF00403.26 CRK21396.1 - 2.1e-16 60.1 0.8 2.5e-16 59.9 0.2 1.4 2 0 0 2 2 2 1 Heavy-metal-associated domain Tcf25 PF04910.14 CRK21398.1 - 8.6e-57 192.8 0.0 1.4e-56 192.1 0.0 1.3 1 0 0 1 1 1 1 Transcriptional repressor TCF25 Acetyltransf_1 PF00583.25 CRK21398.1 - 0.028 14.6 0.0 0.067 13.4 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family RNA_polI_A34 PF08208.11 CRK21398.1 - 0.093 12.8 23.0 0.18 11.9 23.0 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 EcsC PF12787.7 CRK21398.1 - 0.25 11.0 0.1 0.25 11.0 0.1 2.3 2 0 0 2 2 2 0 EcsC protein family CCDC106 PF15794.5 CRK21398.1 - 0.78 9.4 8.9 1.7 8.3 8.9 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 TFIIF_alpha PF05793.12 CRK21398.1 - 1.1 7.8 25.1 2 6.9 25.1 1.5 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) YL1 PF05764.13 CRK21398.1 - 1.5 8.9 25.9 3.3 7.8 25.9 1.6 1 0 0 1 1 1 0 YL1 nuclear protein DUF3402 PF11882.8 CRK21398.1 - 1.8 7.6 6.1 3.2 6.7 6.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) CCDC53 PF10152.9 CRK21398.1 - 4 7.9 12.7 51 4.3 0.0 2.5 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex CDC45 PF02724.14 CRK21398.1 - 4 5.6 21.9 0.83 7.9 18.5 1.6 2 0 0 2 2 2 0 CDC45-like protein RRN3 PF05327.11 CRK21398.1 - 7.9 4.9 12.9 13 4.1 12.9 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SDA1 PF05285.12 CRK21398.1 - 9.2 5.6 29.2 17 4.7 29.2 1.3 1 0 0 1 1 1 0 SDA1 LSM14 PF12701.7 CRK21400.1 - 2.3e-31 107.7 0.1 3.7e-31 107.0 0.1 1.3 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 CRK21400.1 - 1e-21 77.7 1.8 1e-21 77.7 1.8 2.2 2 0 0 2 2 2 1 FDF domain SM-ATX PF14438.6 CRK21400.1 - 4e-07 30.1 0.0 8e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain Acetyltransf_10 PF13673.7 CRK21402.1 - 2.1e-05 24.4 0.1 0.027 14.4 0.0 2.3 1 1 1 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CRK21402.1 - 4.4e-05 23.7 0.0 0.00022 21.5 0.0 2.1 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_5 PF13444.6 CRK21402.1 - 0.00059 20.5 0.0 1.5 9.5 0.0 2.9 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CRK21402.1 - 0.0032 17.9 0.0 0.0086 16.5 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CRK21402.1 - 0.013 15.7 0.0 0.021 15.0 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Ribosomal_S7 PF00177.21 CRK21403.1 - 9.8e-22 77.2 0.0 1.3e-21 76.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Ribosomal_S25 PF03297.15 CRK21404.1 - 1.7e-33 114.8 2.8 1.8e-33 114.7 2.8 1.0 1 0 0 1 1 1 1 S25 ribosomal protein MarR_2 PF12802.7 CRK21404.1 - 0.00064 19.6 0.0 0.0008 19.3 0.0 1.2 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 CRK21404.1 - 0.0053 16.3 0.0 0.007 15.9 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR PF01047.22 CRK21404.1 - 0.023 14.6 0.0 0.036 14.0 0.0 1.3 1 0 0 1 1 1 0 MarR family HTH_DeoR PF08220.12 CRK21404.1 - 0.045 13.5 0.1 0.093 12.5 0.1 1.5 1 1 0 1 1 1 0 DeoR-like helix-turn-helix domain Rrf2 PF02082.20 CRK21404.1 - 0.045 14.1 0.0 0.062 13.6 0.0 1.3 1 0 0 1 1 1 0 Transcriptional regulator Mito_carr PF00153.27 CRK21405.1 - 3.3e-66 219.3 3.6 6.3e-24 83.7 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4748 PF15932.5 CRK21405.1 - 0.031 14.0 0.8 0.1 12.4 0.8 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) Cupredoxin_1 PF13473.6 CRK21406.1 - 0.00026 21.1 0.0 0.001 19.2 0.0 1.8 2 0 0 2 2 2 1 Cupredoxin-like domain GRP PF07172.11 CRK21406.1 - 3.3 8.5 15.4 6.6 7.5 15.4 1.4 1 0 0 1 1 1 0 Glycine rich protein family Cyt-b5 PF00173.28 CRK21407.1 - 3.8e-11 43.0 0.1 5.7e-11 42.4 0.1 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF489 PF04356.12 CRK21408.1 - 0.54 10.2 5.6 0.9 9.5 0.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF489) COG2 PF06148.11 CRK21408.1 - 3.1 7.9 7.8 0.55 10.3 1.7 2.7 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 RcpB PF16971.5 CRK21410.1 - 0.044 13.7 0.0 0.083 12.8 0.0 1.4 1 0 0 1 1 1 0 Rough colony protein B, tight adherence - tad - subunit BTB_2 PF02214.22 CRK21411.1 - 2e-05 24.9 0.1 0.003 17.9 0.0 2.3 2 0 0 2 2 2 2 BTB/POZ domain adh_short_C2 PF13561.6 CRK21412.1 - 2.2e-46 158.3 0.4 2.5e-46 158.1 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRK21412.1 - 5.7e-42 143.4 0.1 7.2e-42 143.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CRK21412.1 - 1e-09 38.5 0.8 1.6e-09 37.9 0.8 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 CRK21412.1 - 0.0072 15.8 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CRK21412.1 - 0.0078 15.7 0.0 0.014 14.9 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family AdoHcyase_NAD PF00670.21 CRK21412.1 - 0.015 15.3 0.1 0.03 14.4 0.1 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_10 PF13460.6 CRK21412.1 - 0.018 15.0 0.1 0.045 13.6 0.1 1.7 1 1 0 1 1 1 0 NAD(P)H-binding DUF2723 PF11028.8 CRK21413.1 - 0.012 15.6 4.3 0.012 15.6 4.3 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2723) Meckelin PF09773.9 CRK21413.1 - 0.035 12.2 1.7 0.056 11.5 1.7 1.2 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) DUF373 PF04123.13 CRK21413.1 - 0.33 10.4 13.0 0.13 11.7 0.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF373) PalH PF08733.10 CRK21413.1 - 0.36 9.8 12.6 1.1 8.2 2.8 2.2 1 1 1 2 2 2 0 PalH/RIM21 DUF4149 PF13664.6 CRK21413.1 - 1.2 9.4 20.2 1.8 8.9 2.2 3.6 2 1 0 3 3 3 0 Domain of unknown function (DUF4149) Claudin_2 PF13903.6 CRK21413.1 - 3.5 7.3 15.8 0.18 11.6 4.9 2.5 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction GWT1 PF06423.12 CRK21413.1 - 7.4 6.7 11.2 1.9 8.6 3.1 2.9 1 1 1 2 2 2 0 GWT1 Fungal_trans PF04082.18 CRK21414.1 - 4.8e-17 61.9 0.1 8.9e-17 61.0 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK21414.1 - 2.2e-07 30.9 15.3 4.1e-07 30.0 15.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HSP70 PF00012.20 CRK21415.1 - 8.9e-59 199.2 15.0 9.4e-57 192.5 12.8 2.5 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CRK21415.1 - 0.0027 16.6 0.3 0.017 13.9 0.0 2.4 3 0 0 3 3 3 1 MreB/Mbl protein Asp PF00026.23 CRK21416.1 - 8.5e-31 107.5 0.0 1e-30 107.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 CRK21416.1 - 0.0056 16.5 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.6 CRK21416.1 - 0.079 13.2 0.0 3.8 7.7 0.0 2.4 2 1 1 3 3 3 0 Xylanase inhibitor N-terminal Bromodomain PF00439.25 CRK21417.1 - 1.9e-08 34.3 0.0 0.022 14.8 0.0 3.4 2 2 0 2 2 2 2 Bromodomain TFIIF_alpha PF05793.12 CRK21417.1 - 8.6 4.8 26.6 3.1 6.3 9.0 2.2 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Spc29 PF17082.5 CRK21418.1 - 0.00012 22.1 0.3 0.00015 21.7 0.3 1.2 1 0 0 1 1 1 1 Spindle Pole Component 29 SKA1 PF07160.12 CRK21418.1 - 0.00022 21.2 1.0 0.00026 20.9 1.0 1.1 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 1 FliD_N PF02465.18 CRK21418.1 - 0.0027 18.3 1.0 0.004 17.8 1.0 1.3 1 0 0 1 1 1 1 Flagellar hook-associated protein 2 N-terminus Filament PF00038.21 CRK21418.1 - 0.0043 16.7 1.5 0.0051 16.5 1.5 1.1 1 0 0 1 1 1 1 Intermediate filament protein SlyX PF04102.12 CRK21418.1 - 0.0054 17.3 4.0 0.0054 17.3 4.0 1.8 1 1 1 2 2 2 1 SlyX DUF4686 PF15742.5 CRK21418.1 - 0.0079 15.4 1.3 0.0099 15.1 1.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4686) XhlA PF10779.9 CRK21418.1 - 0.0089 16.2 2.4 0.014 15.6 2.4 1.2 1 0 0 1 1 1 1 Haemolysin XhlA DUF16 PF01519.16 CRK21418.1 - 0.018 15.5 1.0 0.025 15.0 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF16 Allexi_40kDa PF05549.11 CRK21418.1 - 0.019 14.5 1.5 0.025 14.1 1.5 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein Spc7 PF08317.11 CRK21418.1 - 0.05 12.5 1.8 0.058 12.3 1.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein BLOC1_2 PF10046.9 CRK21418.1 - 0.17 12.2 2.0 0.39 11.0 2.0 1.6 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fib_alpha PF08702.10 CRK21418.1 - 0.32 11.2 3.6 0.074 13.2 0.8 1.4 2 0 0 2 2 1 0 Fibrinogen alpha/beta chain family DUF4407 PF14362.6 CRK21418.1 - 0.35 10.2 2.3 0.38 10.1 2.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CytochromB561_N PF09786.9 CRK21418.1 - 0.42 9.6 4.9 0.49 9.3 4.9 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal GREB1 PF15782.5 CRK21418.1 - 3.8 4.5 5.6 4.1 4.4 5.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Shisa PF13908.6 CRK21418.1 - 8.4 6.6 10.7 5.7 7.1 9.1 1.4 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator PIGA PF08288.12 CRK21419.1 - 1e-45 154.2 3.4 1.7e-45 153.5 1.1 2.2 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 CRK21419.1 - 2.4e-27 96.0 0.5 3.9e-27 95.3 0.5 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 CRK21419.1 - 1.3e-26 93.2 0.0 1.8e-26 92.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CRK21419.1 - 9.1e-23 81.2 0.1 1.4e-22 80.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 CRK21419.1 - 1.5e-11 45.0 0.0 3.2e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 CRK21419.1 - 2.5e-06 27.8 0.0 2.5e-05 24.6 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 CRK21419.1 - 0.0022 18.0 0.1 0.0041 17.1 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like PBP1_TM PF14812.6 CRK21419.1 - 0.042 14.2 2.1 0.049 14.0 0.1 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DEAD PF00270.29 CRK21420.1 - 3.2e-33 115.0 0.0 6.4e-17 61.9 0.0 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 CRK21420.1 - 3.7e-20 72.3 0.0 9.3e-20 71.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CRK21420.1 - 6.6e-08 32.7 0.0 1.7e-07 31.4 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 CRK21420.1 - 0.012 15.2 1.8 0.015 14.8 0.0 2.0 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain BUD22 PF09073.10 CRK21420.1 - 0.28 10.5 25.2 0.14 11.5 4.1 2.2 2 0 0 2 2 2 0 BUD22 RR_TM4-6 PF06459.12 CRK21420.1 - 0.86 9.4 16.1 6.3 6.5 12.4 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 RNA_pol_Rpc4 PF05132.14 CRK21420.1 - 1.5 9.2 14.6 8 6.9 0.1 2.7 2 0 0 2 2 2 0 RNA polymerase III RPC4 Cwf_Cwc_15 PF04889.12 CRK21420.1 - 6.3 6.5 26.1 4 7.1 8.4 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein CCDC106 PF15794.5 CRK21420.1 - 6.8 6.3 21.3 0.61 9.8 3.6 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 DIOX_N PF14226.6 CRK21421.1 - 5.1e-05 24.0 0.0 0.00012 22.8 0.0 1.7 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 CRK21421.1 - 0.00013 22.4 0.0 0.00023 21.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily NAD_binding_10 PF13460.6 CRK21422.1 - 0.0003 20.8 0.0 0.00044 20.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Oxidored_FMN PF00724.20 CRK21423.1 - 4.3e-07 29.5 0.0 5.1e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family E1-E2_ATPase PF00122.20 CRK21424.1 - 7.9e-17 61.4 0.4 7.9e-17 61.4 0.4 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 CRK21424.1 - 3.5e-07 29.8 0.1 1.4e-06 27.9 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus DUF2976 PF11190.8 CRK21424.1 - 0.058 13.2 1.3 0.13 12.1 1.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) DUF1295 PF06966.12 CRK21424.1 - 0.094 12.2 0.2 0.13 11.7 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) Bromodomain PF00439.25 CRK21425.1 - 5e-18 64.9 0.2 6.3e-18 64.6 0.2 1.1 1 0 0 1 1 1 1 Bromodomain AT_hook PF02178.19 CRK21425.1 - 0.055 13.4 1.0 0.055 13.4 1.0 2.7 3 0 0 3 3 3 0 AT hook motif DUF4448 PF14610.6 CRK21428.1 - 0.087 12.6 0.4 0.13 12.1 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Insulin_TMD PF17870.1 CRK21428.1 - 7.9 6.6 9.0 1.1 9.4 0.8 2.8 3 0 0 3 3 3 0 Insulin receptor trans-membrane segment ABC2_membrane PF01061.24 CRK21431.1 - 3.3e-17 62.6 3.0 3.5e-17 62.5 3.0 1.0 1 0 0 1 1 1 1 ABC-2 type transporter AMP-binding PF00501.28 CRK21434.1 - 3.6e-26 91.7 0.3 4e-26 91.6 0.3 1.0 1 0 0 1 1 1 1 AMP-binding enzyme CNH PF00780.22 CRK21435.1 - 5.7e-35 121.2 0.0 6.7e-35 121.0 0.0 1.1 1 0 0 1 1 1 1 CNH domain Lipase_3 PF01764.25 CRK21465.1 - 8.2e-14 51.7 0.0 5.7e-12 45.7 0.0 2.5 1 1 0 1 1 1 1 Lipase (class 3) Acetyltransf_1 PF00583.25 CRK21466.1 - 1.8e-10 41.1 0.0 2.2e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CRK21466.1 - 3.1e-08 33.9 0.3 4.5e-08 33.4 0.3 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CRK21466.1 - 1e-06 28.7 0.0 1.4e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AstA PF04958.12 CRK21466.1 - 0.033 12.7 0.0 0.046 12.3 0.0 1.2 1 0 0 1 1 1 0 Arginine N-succinyltransferase beta subunit adh_short_C2 PF13561.6 CRK21467.1 - 9.9e-55 185.6 0.4 1.2e-54 185.3 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRK21467.1 - 1.1e-49 168.6 0.2 1.4e-49 168.3 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CRK21467.1 - 1.1e-12 48.3 1.0 3.2e-12 46.7 1.0 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 CRK21467.1 - 1.7e-06 27.6 0.0 2.2e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 CRK21467.1 - 0.06 12.4 0.1 0.094 11.8 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain ADH_N PF08240.12 CRK21468.1 - 3.4e-28 97.7 0.5 3.4e-28 97.7 0.5 2.2 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CRK21468.1 - 2.2e-17 63.3 0.8 4.3e-17 62.3 0.8 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 CRK21468.1 - 8.9e-09 35.1 1.1 0.0024 17.4 0.2 2.6 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus 2-Hacid_dh_C PF02826.19 CRK21468.1 - 0.0029 17.0 0.1 0.0079 15.6 0.1 1.7 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 CRK21468.1 - 0.0038 16.5 3.7 0.0038 16.5 3.7 1.9 1 1 1 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 CRK21468.1 - 0.0047 16.8 0.8 0.0088 15.9 0.8 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain YdfZ PF14001.6 CRK21468.1 - 0.0068 16.8 0.2 0.49 10.8 0.0 2.9 2 1 0 2 2 2 1 YdfZ protein UDPG_MGDP_dh_N PF03721.14 CRK21468.1 - 0.012 15.2 2.2 0.016 14.8 0.4 2.0 2 1 1 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF1272 PF06906.11 CRK21468.1 - 0.072 13.2 0.5 12 6.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) HI0933_like PF03486.14 CRK21468.1 - 0.081 11.6 1.2 0.12 11.0 1.2 1.2 1 0 0 1 1 1 0 HI0933-like protein TrkA_N PF02254.18 CRK21468.1 - 0.1 12.8 0.6 0.44 10.8 0.1 2.2 2 0 0 2 2 2 0 TrkA-N domain Aldo_ket_red PF00248.21 CRK21469.1 - 6.7e-13 48.5 0.0 2.8e-07 30.0 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family SNARE PF05739.19 CRK21470.1 - 4.8e-12 45.7 0.1 4.8e-12 45.7 0.1 1.9 2 0 0 2 2 2 1 SNARE domain Syntaxin-5_N PF11416.8 CRK21470.1 - 8.5e-10 37.6 0.5 2.2e-09 36.2 0.5 1.8 1 0 0 1 1 1 1 Syntaxin-5 N-terminal, Sly1p-binding domain KxDL PF10241.9 CRK21470.1 - 5.3e-05 23.4 4.1 0.0062 16.8 0.1 3.6 4 0 0 4 4 4 1 Uncharacterized conserved protein Prominin PF05478.11 CRK21470.1 - 0.0034 15.4 1.7 0.48 8.3 0.0 2.2 2 0 0 2 2 2 2 Prominin Syntaxin PF00804.25 CRK21470.1 - 0.007 16.1 0.1 0.007 16.1 0.1 2.9 2 1 1 3 3 3 1 Syntaxin Syntaxin-18_N PF10496.9 CRK21470.1 - 0.026 14.8 2.9 0.087 13.1 0.1 2.7 3 0 0 3 3 3 0 SNARE-complex protein Syntaxin-18 N-terminus DUF4988 PF16378.5 CRK21470.1 - 0.049 13.3 5.7 3.8 7.1 0.3 3.2 2 1 1 3 3 3 0 Domain of unknown function DUF2408 PF10303.9 CRK21470.1 - 0.052 14.1 0.9 0.23 12.0 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) TRPM_tetra PF16519.5 CRK21470.1 - 0.06 13.5 2.2 0.21 11.7 0.2 2.9 4 0 0 4 4 3 0 Tetramerisation domain of TRPM DegS PF05384.11 CRK21470.1 - 0.071 12.6 3.4 4.7 6.7 0.6 2.6 2 1 0 2 2 2 0 Sensor protein DegS SF-assemblin PF06705.11 CRK21470.1 - 0.79 9.0 8.2 0.088 12.1 0.6 2.4 3 0 0 3 3 3 0 SF-assemblin/beta giardin SOAR PF16533.5 CRK21470.1 - 1.3 9.1 4.2 0.6 10.1 0.1 2.4 3 0 0 3 3 3 0 STIM1 Orai1-activating region NPV_P10 PF05531.12 CRK21470.1 - 1.3 9.5 5.8 32 5.1 2.2 3.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF16 PF01519.16 CRK21470.1 - 1.7 9.1 5.4 3.5 8.2 0.8 2.6 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF5344 PF17279.2 CRK21470.1 - 2.7 8.6 6.4 14 6.3 1.2 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5344) Sec2p PF06428.11 CRK21472.1 - 1.4e-26 92.3 19.1 1.4e-26 92.3 19.1 2.4 2 1 0 2 2 2 1 GDP/GTP exchange factor Sec2p DUF5401 PF17380.2 CRK21472.1 - 0.00022 19.5 9.5 0.00033 18.9 9.5 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5401) AAA_15 PF13175.6 CRK21472.1 - 0.063 13.0 4.9 0.089 12.5 4.9 1.1 1 0 0 1 1 1 0 AAA ATPase domain DUF3439 PF11921.8 CRK21472.1 - 0.13 12.3 1.3 0.25 11.3 1.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF5339 PF17274.2 CRK21472.1 - 0.21 12.4 14.7 1.2 10.0 5.5 3.4 2 1 1 3 3 3 0 Family of unknown function (DUF5339) DUF3584 PF12128.8 CRK21472.1 - 2.1 5.7 21.9 2.8 5.3 21.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) PMT PF02366.18 CRK21473.1 - 1.8e-73 247.2 30.4 3.2e-72 243.0 16.7 2.8 3 0 0 3 3 3 2 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 CRK21473.1 - 3.7e-67 225.8 15.6 3.7e-67 225.8 15.6 2.6 3 0 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 CRK21473.1 - 4.3e-47 160.4 0.4 8.9e-47 159.3 0.0 1.7 2 0 0 2 2 2 1 MIR domain Mucin_bdg PF03272.13 CRK21473.1 - 0.041 13.9 0.0 0.26 11.3 0.0 2.3 2 0 0 2 2 2 0 Putative mucin or carbohydrate-binding module Response_reg PF00072.24 CRK21474.1 - 2.6e-21 75.9 0.0 7.3e-15 55.1 0.0 2.4 2 0 0 2 2 2 2 Response regulator receiver domain MARVEL PF01284.23 CRK21475.1 - 1.1e-05 25.5 19.0 0.00013 22.0 20.3 2.0 1 1 1 2 2 2 1 Membrane-associating domain DUF1294 PF06961.13 CRK21475.1 - 0.099 12.9 0.8 0.55 10.5 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1294) DUF4234 PF14018.6 CRK21475.1 - 3.3 7.9 9.7 1.1 9.5 4.7 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4234) BAR PF03114.18 CRK21479.1 - 7.8e-13 48.6 0.3 1.6e-12 47.6 0.2 1.5 1 1 1 2 2 2 1 BAR domain SH3_1 PF00018.28 CRK21479.1 - 2.7e-12 46.1 0.1 5.2e-12 45.2 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CRK21479.1 - 1.4e-08 34.4 0.0 2.5e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CRK21479.1 - 7.8e-07 28.7 0.0 1.3e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Caskin-Pro-rich PF16907.5 CRK21479.1 - 0.0093 16.5 5.0 0.018 15.5 3.6 2.2 2 0 0 2 2 2 1 Proline rich region of Caskin proteins Laminin_II PF06009.12 CRK21479.1 - 0.029 14.4 1.4 1.4 8.9 0.4 2.5 3 0 0 3 3 3 0 Laminin Domain II Med3 PF11593.8 CRK21479.1 - 0.33 10.1 11.0 0.68 9.1 11.0 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF2439 PF10382.9 CRK21480.1 - 1.2e-25 89.7 0.1 3e-25 88.3 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) dCMP_cyt_deam_1 PF00383.23 CRK21481.1 - 1.3e-20 73.1 0.3 1.6e-19 69.6 0.0 2.7 2 1 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CRK21481.1 - 6.9e-18 64.7 0.2 1.9e-08 34.1 0.1 3.0 3 0 0 3 3 3 2 MafB19-like deaminase Bd3614-deam PF14439.6 CRK21481.1 - 0.0014 18.7 0.1 0.017 15.2 0.0 2.3 2 0 0 2 2 2 1 Bd3614-like deaminase Zn_clus PF00172.18 CRK21481.1 - 0.48 10.6 9.4 0.86 9.8 9.4 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Xan_ur_permease PF00860.20 CRK21483.1 - 1.2e-28 99.9 22.8 5.9e-27 94.4 22.8 2.2 1 1 0 1 1 1 1 Permease family Sulfate_transp PF00916.20 CRK21483.1 - 0.00052 18.9 15.8 0.00094 18.0 13.6 2.3 1 1 1 2 2 2 1 Sulfate permease family MFS_MOT1 PF16983.5 CRK21483.1 - 1.1 9.7 16.0 0.26 11.7 5.5 3.2 2 1 0 2 2 2 0 Molybdate transporter of MFS superfamily DUF4956 PF16316.5 CRK21483.1 - 3.9 7.1 9.7 0.56 9.8 0.1 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4956) DUF3488 PF11992.8 CRK21483.1 - 9.2 5.1 9.7 0.34 9.8 2.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3488) NADH-u_ox-rdase PF10785.9 CRK21484.1 - 2.5e-28 98.6 0.1 5.5e-28 97.5 0.1 1.6 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.7 CRK21484.1 - 8.2e-27 93.0 0.0 1.2e-26 92.5 0.0 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Swi3 PF07962.12 CRK21485.1 - 3.9e-30 103.7 0.2 5.5e-30 103.2 0.2 1.2 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 BDHCT_assoc PF16204.5 CRK21485.1 - 3.8 7.1 5.2 0.32 10.7 0.2 1.7 2 0 0 2 2 2 0 BDHCT-box associated domain on Bloom syndrome protein bZIP_2 PF07716.15 CRK21486.1 - 1.5e-06 28.2 17.4 3e-06 27.2 17.4 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 CRK21486.1 - 0.00015 21.8 15.1 0.00027 21.0 15.1 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 CRK21486.1 - 0.00067 20.1 10.3 0.0013 19.2 10.3 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor NTP_transf_9 PF04248.12 CRK21487.1 - 5e-26 90.4 0.3 6.5e-26 90.1 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF427) Ribosomal_S19 PF00203.21 CRK21489.1 - 2.2e-29 101.2 0.1 2.3e-29 101.1 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19 malic PF00390.19 CRK21491.1 - 0.096 12.5 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Malic enzyme, N-terminal domain tRNA-synt_2c PF01411.19 CRK21493.1 - 7.2e-25 87.5 0.1 7.9e-25 87.4 0.1 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (A) MIF PF01187.18 CRK21493.1 - 0.032 14.5 0.0 0.047 14.0 0.0 1.3 1 0 0 1 1 1 0 Macrophage migration inhibitory factor (MIF) Mito_carr PF00153.27 CRK21498.1 - 2e-31 107.7 3.7 8.1e-22 77.0 0.4 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein Amidase_5 PF05382.13 CRK21498.1 - 0.059 13.3 0.2 0.087 12.7 0.1 1.4 1 1 0 1 1 1 0 Bacteriophage peptidoglycan hydrolase HMMR_N PF15905.5 CRK21499.1 - 0.022 14.2 2.6 0.039 13.4 2.6 1.4 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal IL11 PF07400.11 CRK21499.1 - 0.028 14.1 0.1 0.036 13.7 0.1 1.1 1 0 0 1 1 1 0 Interleukin 11 Spectrin PF00435.21 CRK21499.1 - 0.031 14.8 2.0 0.039 14.4 2.0 1.1 1 0 0 1 1 1 0 Spectrin repeat APG6_N PF17675.1 CRK21499.1 - 0.041 14.4 2.2 0.056 14.0 2.2 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region GSAP-16 PF14959.6 CRK21499.1 - 0.16 11.9 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 gamma-Secretase-activating protein C-term bZIP_1 PF00170.21 CRK21499.1 - 0.42 10.7 4.9 12 6.1 2.9 2.1 1 1 1 2 2 2 0 bZIP transcription factor Cep57_CLD_2 PF14197.6 CRK21499.1 - 0.86 9.7 5.5 5.8 7.1 5.6 2.0 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 MucB_RseB_C PF17188.4 CRK21517.1 - 0.087 13.1 0.2 17 5.7 0.0 2.4 2 0 0 2 2 2 0 MucB/RseB C-terminal domain DNA_pol_phi PF04931.13 CRK21517.1 - 0.64 8.0 18.7 0.97 7.5 18.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi tRNA-synt_1 PF00133.22 CRK21519.1 - 3.6e-115 385.5 0.0 4.4e-112 375.3 0.0 3.2 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 CRK21519.1 - 4.2e-15 55.4 0.0 1.4e-07 30.6 0.0 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 CRK21519.1 - 1.3e-12 47.9 0.0 3.1e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA zf-FPG_IleRS PF06827.14 CRK21519.1 - 0.5 10.3 4.4 1.1 9.2 4.4 1.6 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS Beta_helix PF13229.6 CRK21523.1 - 3.9e-13 49.5 21.7 1.2e-09 38.2 9.0 3.6 1 1 2 3 3 3 2 Right handed beta helix region NosD PF05048.13 CRK21523.1 - 5.5e-05 22.5 10.2 0.0034 16.7 3.4 2.9 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) TPT PF03151.16 CRK21525.1 - 7.1e-05 22.3 0.7 0.0001 21.7 0.7 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family DUF4236 PF14020.6 CRK21525.1 - 0.088 13.4 0.6 0.34 11.5 0.6 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4236) Motilin_ghrelin PF04644.12 CRK21525.1 - 0.25 11.2 3.6 0.7 9.7 3.6 1.8 1 0 0 1 1 1 0 Motilin/ghrelin Beta_helix PF13229.6 CRK21527.1 - 8.1e-10 38.8 16.1 4.8e-08 33.0 3.0 2.8 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.13 CRK21527.1 - 4.4e-05 22.9 0.4 0.0023 17.2 0.0 2.2 1 1 1 2 2 2 2 Periplasmic copper-binding protein (NosD) Alginate_lyase PF05426.12 CRK21528.1 - 1.8e-10 40.9 0.5 2.3e-10 40.5 0.5 1.2 1 0 0 1 1 1 1 Alginate lyase Patatin PF01734.22 CRK21530.1 - 4.1e-13 50.0 0.3 4.7e-13 49.8 0.3 1.1 1 0 0 1 1 1 1 Patatin-like phospholipase DUF3852 PF12963.7 CRK21534.1 - 0.16 12.3 1.5 1.1 9.7 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3852) Enoyl_reductase PF12241.8 CRK21534.1 - 0.17 11.2 0.1 0.27 10.5 0.1 1.3 1 0 0 1 1 1 0 Trans-2-enoyl-CoA reductase catalytic region RVT_1 PF00078.27 CRK21535.1 - 4.1e-36 124.6 0.0 6.3e-36 124.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) cEGF PF12662.7 CRK21538.1 - 0.068 13.1 0.1 0.16 11.9 0.1 1.6 1 0 0 1 1 1 0 Complement Clr-like EGF-like hEGF PF12661.7 CRK21538.1 - 0.13 12.9 0.8 0.13 12.9 0.8 2.2 2 0 0 2 2 2 0 Human growth factor-like EGF RRP36 PF06102.12 CRK21540.1 - 0.05 13.6 0.0 0.06 13.3 0.0 1.1 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 Gp-FAR-1 PF05823.12 CRK21540.1 - 0.06 13.7 0.0 0.08 13.3 0.0 1.1 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF1192 PF06698.11 CRK21540.1 - 0.12 12.4 2.7 0.26 11.4 2.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1192) ZapB PF06005.12 CRK21540.1 - 0.44 11.0 2.1 1.6 9.2 2.2 1.7 1 1 0 1 1 1 0 Cell division protein ZapB Ank_2 PF12796.7 CRK21542.1 - 2.8e-11 43.9 0.1 0.00045 20.7 0.0 4.0 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CRK21542.1 - 4.6e-07 30.0 0.9 0.22 11.9 0.0 4.7 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 CRK21542.1 - 1.5e-06 28.4 1.0 1.9 9.1 0.0 5.4 5 0 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.6 CRK21542.1 - 7.6e-06 25.9 4.0 3.8 8.4 0.0 7.1 9 0 0 9 9 9 1 Ankyrin repeat F-box PF00646.33 CRK21542.1 - 0.015 15.1 0.6 0.03 14.2 0.6 1.5 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 CRK21542.1 - 0.044 13.7 0.8 0.1 12.5 0.8 1.6 1 0 0 1 1 1 0 F-box-like C5HCH PF17982.1 CRK21543.1 - 0.046 13.9 1.7 0.095 12.9 1.7 1.5 1 0 0 1 1 1 0 NSD Cys-His rich domain BRCT PF00533.26 CRK21545.1 - 4.9e-08 33.2 0.0 0.003 17.9 0.0 2.4 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 CRK21545.1 - 4.4e-06 27.0 0.1 0.12 12.8 0.0 2.2 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 CRK21545.1 - 0.0036 17.2 0.0 0.066 13.2 0.0 2.5 2 0 0 2 2 2 1 twin BRCT domain SRF-TF PF00319.18 CRK21547.1 - 0.026 14.0 0.1 0.06 12.8 0.1 1.5 1 0 0 1 1 1 0 SRF-type transcription factor (DNA-binding and dimerisation domain) Ferric_reduct PF01794.19 CRK21549.1 - 0.002 18.3 0.5 0.002 18.3 0.5 2.1 2 1 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 CRK21551.1 - 0.004 17.3 0.3 0.014 15.5 0.1 1.9 1 1 1 2 2 2 1 Ferric reductase NAD binding domain SieB PF14163.6 CRK21551.1 - 0.19 11.2 0.0 0.37 10.3 0.0 1.5 1 0 0 1 1 1 0 Super-infection exclusion protein B BRCT PF00533.26 CRK21552.1 - 6.1e-08 32.9 0.1 6.7e-08 32.8 0.1 1.0 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 CRK21552.1 - 1.8e-06 27.8 0.1 2.2e-06 27.5 0.1 1.3 1 1 0 1 1 1 1 twin BRCT domain PTCB-BRCT PF12738.7 CRK21553.1 - 2.6e-06 27.3 0.0 5e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 CRK21553.1 - 4.3e-06 27.0 0.3 1.1e-05 25.8 0.1 1.9 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 CRK21553.1 - 0.00011 22.5 0.3 0.00047 20.5 0.1 2.0 2 1 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain CENP-B_dimeris PF09026.10 CRK21553.1 - 0.48 10.8 4.4 22 5.5 2.3 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain D123 PF07065.14 CRK21553.1 - 1.8 7.6 5.6 0.7 9.0 0.6 2.1 2 0 0 2 2 2 0 D123 PBP1_TM PF14812.6 CRK21553.1 - 1.8 9.0 6.8 1.1 9.7 2.2 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.6 CRK21553.1 - 3 7.5 9.3 1.6 8.4 3.0 2.2 2 0 0 2 2 2 0 FAM176 family S-antigen PF05756.11 CRK21553.1 - 9.6 6.7 6.7 5 7.6 1.2 2.3 2 0 0 2 2 2 0 S-antigen protein F-box_4 PF15966.5 CRK21554.1 - 3.1e-06 27.1 0.1 8e-06 25.7 0.1 1.7 1 0 0 1 1 1 1 F-box F-box-like PF12937.7 CRK21554.1 - 0.00033 20.5 0.6 0.0028 17.5 0.1 2.4 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 CRK21554.1 - 0.03 14.8 2.6 2.9 8.4 0.0 3.3 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) RhoGAP PF00620.27 CRK21554.1 - 0.061 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 RhoGAP domain F-box PF00646.33 CRK21554.1 - 0.13 12.2 1.0 1.7 8.7 0.0 2.7 2 0 0 2 2 2 0 F-box domain ASH PF15780.5 CRK21555.1 - 0.063 13.5 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin SRF-TF PF00319.18 CRK21556.1 - 1.5e-05 24.4 0.4 1.9e-05 24.0 0.4 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF3435 PF11917.8 CRK21557.1 - 0.023 13.6 0.0 0.038 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) RRN3 PF05327.11 CRK21559.1 - 8.4e-38 130.2 1.3 9.2e-38 130.1 1.3 1.0 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 NOA36 PF06524.12 CRK21559.1 - 0.33 10.2 10.6 0.37 10.1 10.6 1.1 1 0 0 1 1 1 0 NOA36 protein PC_rep PF01851.22 CRK21563.1 - 5.4e-23 80.2 14.2 1.7e-06 28.2 0.3 4.2 4 0 0 4 4 4 4 Proteasome/cyclosome repeat Actin PF00022.19 CRK21566.1 - 2.2e-08 33.1 0.0 2.2e-08 33.1 0.0 1.0 1 0 0 1 1 1 1 Actin Drf_FH3 PF06367.16 CRK21567.1 - 4.2e-12 46.1 1.9 4.2e-12 46.1 0.1 1.9 2 1 0 2 2 2 1 Diaphanous FH3 Domain SlyX PF04102.12 CRK21567.1 - 0.043 14.4 3.5 0.043 14.4 3.5 2.2 1 1 1 2 2 2 0 SlyX Bap31_Bap29_C PF18035.1 CRK21567.1 - 0.42 10.6 12.8 0.081 12.9 6.3 2.5 2 1 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain Rx_N PF18052.1 CRK21567.1 - 1.6 9.1 8.2 2.2 8.6 1.6 2.4 1 1 2 3 3 2 0 Rx N-terminal domain DivIC PF04977.15 CRK21567.1 - 3.7 7.4 8.3 0.57 10.0 3.3 2.1 2 0 0 2 2 2 0 Septum formation initiator GTA_holin_3TM PF11351.8 CRK21567.1 - 3.8 8.1 7.0 11 6.5 7.0 2.0 2 1 0 2 2 2 0 Holin of 3TMs, for gene-transfer release SLX9 PF15341.6 CRK21567.1 - 9.3 6.7 8.2 3.3 8.1 1.6 2.1 1 1 1 2 2 2 0 Ribosome biogenesis protein SLX9 E1-E2_ATPase PF00122.20 CRK21572.1 - 3.1e-05 23.6 0.0 5.3e-05 22.8 0.0 1.5 1 1 0 1 1 1 1 E1-E2 ATPase Aconitase_C PF00694.19 CRK21573.1 - 3.8e-39 134.0 0.0 4.1e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 Aconitase C-terminal domain NAD_Gly3P_dh_C PF07479.14 CRK21574.1 - 3.7e-30 105.1 0.9 4e-30 105.0 0.9 1.0 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus Glyco_hydro_6 PF01341.17 CRK21576.1 - 0.00092 19.0 0.0 0.0012 18.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 adh_short PF00106.25 CRK21577.1 - 7.7e-14 51.6 0.2 1.2e-13 51.0 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK21577.1 - 2.4e-11 43.7 0.2 3e-11 43.4 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase TRI12 PF06609.13 CRK21580.1 - 7.1e-36 123.8 13.4 1.4e-35 122.8 9.5 2.0 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) GRDP-like PF07173.12 CRK21580.1 - 5.1e-14 53.1 6.1 1.8e-10 41.6 0.0 3.2 3 1 0 3 3 3 2 Glycine-rich domain-containing protein-like MFS_1 PF07690.16 CRK21580.1 - 2e-12 46.8 26.7 2e-12 46.8 26.7 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily Ribosomal_S21e PF01249.18 CRK21583.1 - 5.2e-41 138.6 0.2 5.8e-41 138.5 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Haem_oxygenas_2 PF14518.6 CRK21583.1 - 0.087 12.6 0.0 0.093 12.5 0.0 1.1 1 0 0 1 1 1 0 Iron-containing redox enzyme NUDIX PF00293.28 CRK21585.1 - 5.4e-06 26.5 0.0 1.3e-05 25.3 0.0 1.7 1 1 0 1 1 1 1 NUDIX domain Sugar_tr PF00083.24 CRK21587.1 - 1e-79 268.5 21.1 1.2e-79 268.3 21.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK21587.1 - 4.2e-29 101.6 24.7 6.8e-29 100.9 24.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1659 PF07872.11 CRK21587.1 - 0.0065 16.1 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1659) Phage_holin_3_2 PF04550.12 CRK21587.1 - 3.3 8.3 8.4 0.54 10.8 2.8 2.4 2 1 1 3 3 3 0 Phage holin family 2 C166 PF17615.2 CRK21591.1 - 2.6e-09 37.4 0.3 7.7e-09 35.9 0.3 1.9 1 1 0 1 1 1 1 Family of unknown function HsbA PF12296.8 CRK21591.1 - 0.00011 22.6 0.5 0.00061 20.2 0.1 2.1 1 1 1 2 2 2 1 Hydrophobic surface binding protein A Fungal_trans PF04082.18 CRK21593.1 - 1.3e-21 76.8 0.0 2.1e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK21593.1 - 1.4e-09 37.9 11.7 2.6e-09 37.0 11.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 4HBT_3 PF13622.6 CRK21595.1 - 3.3e-16 60.3 0.1 3.3e-16 60.3 0.1 2.1 2 1 0 2 2 2 1 Thioesterase-like superfamily 2-Hacid_dh_C PF02826.19 CRK21597.1 - 1.2e-43 148.5 0.0 2.1e-29 102.2 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain XdhC_C PF13478.6 CRK21597.1 - 0.39 11.2 1.9 1.3 9.6 0.0 2.6 3 0 0 3 3 3 0 XdhC Rossmann domain ADH_N PF08240.12 CRK21599.1 - 6.6e-26 90.3 1.6 1.2e-25 89.5 1.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CRK21599.1 - 1.4e-14 54.2 0.0 2.5e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.21 CRK21599.1 - 0.25 11.0 0.5 0.46 10.2 0.5 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Vta1 PF04652.16 CRK21602.1 - 3.1e-53 179.6 2.2 4e-53 179.3 2.2 1.1 1 0 0 1 1 1 1 Vta1 like Vta1_C PF18097.1 CRK21602.1 - 2.8e-14 52.5 0.7 6.5e-14 51.4 0.0 1.9 2 0 0 2 2 2 1 Vta1 C-terminal domain Thioredoxin PF00085.20 CRK21604.1 - 6.2e-33 112.9 0.0 3.6e-26 91.1 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 CRK21604.1 - 3.3e-06 27.5 0.0 0.028 14.9 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 CRK21604.1 - 2.7e-05 23.7 0.0 0.00012 21.6 0.0 1.8 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 CRK21604.1 - 6.2e-05 23.2 0.0 4 7.8 0.0 4.0 3 1 1 4 4 4 2 Thioredoxin-like AhpC-TSA PF00578.21 CRK21604.1 - 0.014 15.3 0.1 0.067 13.1 0.0 2.1 2 0 0 2 2 2 0 AhpC/TSA family HyaE PF07449.11 CRK21604.1 - 0.028 14.4 0.0 2.2 8.3 0.0 2.7 2 1 0 2 2 2 0 Hydrogenase-1 expression protein HyaE QSOX_Trx1 PF18108.1 CRK21604.1 - 0.046 13.9 0.0 0.13 12.4 0.0 1.7 2 0 0 2 2 2 0 QSOX Trx-like domain TraF PF13728.6 CRK21604.1 - 0.07 12.9 0.0 0.07 12.9 0.0 3.4 4 0 0 4 4 4 0 F plasmid transfer operon protein Thioredoxin_3 PF13192.6 CRK21604.1 - 0.13 12.3 0.1 5.1 7.2 0.0 2.6 2 0 0 2 2 2 0 Thioredoxin domain Glutaredoxin PF00462.24 CRK21604.1 - 0.16 12.2 0.1 15 5.9 0.0 2.5 2 0 0 2 2 2 0 Glutaredoxin RNase_PH PF01138.21 CRK21606.1 - 1.7e-35 122.4 0.1 2.7e-35 121.7 0.1 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 NIF PF03031.18 CRK21609.1 - 9e-37 126.2 0.0 1.3e-36 125.8 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ABM PF03992.16 CRK21613.1 - 0.13 12.4 0.6 0.28 11.3 0.1 1.8 2 0 0 2 2 2 0 Antibiotic biosynthesis monooxygenase Pro_dh PF01619.18 CRK21618.1 - 1.7e-69 234.6 0.1 2.2e-69 234.3 0.1 1.1 1 0 0 1 1 1 1 Proline dehydrogenase DUF2749 PF10907.8 CRK21618.1 - 0.11 12.6 0.6 0.38 11.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) CGI-121 PF08617.10 CRK21619.1 - 1e-52 178.5 0.0 1.2e-52 178.3 0.0 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 MlrC_C PF07171.12 CRK21619.1 - 0.054 13.7 0.0 0.099 12.8 0.0 1.4 1 0 0 1 1 1 0 MlrC C-terminus Zn_clus PF00172.18 CRK21621.1 - 2.8e-07 30.5 6.9 4.6e-07 29.9 6.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_1 PF00561.20 CRK21623.1 - 4.8e-13 49.4 3.6 4.2e-11 43.0 1.5 2.4 2 1 0 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CRK21623.1 - 5.6e-12 46.7 0.9 9.4e-12 46.0 0.9 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CRK21623.1 - 5.1e-11 42.3 0.4 8.1e-11 41.6 0.4 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 CRK21623.1 - 0.0086 16.2 0.1 0.014 15.6 0.1 1.3 1 0 0 1 1 1 1 Thioesterase domain Peptidase_S15 PF02129.18 CRK21623.1 - 0.16 11.6 0.2 0.45 10.1 0.1 1.6 1 1 1 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Glyco_hydro_115 PF15979.5 CRK21626.1 - 1.2e-36 126.9 0.3 1.5e-36 126.6 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 115 MFS_1 PF07690.16 CRK21640.1 - 4.8e-07 29.0 12.6 4.8e-07 29.0 12.6 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily TetR_C_34 PF17929.1 CRK21640.1 - 0.072 13.2 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Pkinase PF00069.25 CRK21652.1 - 1.5e-42 145.8 0.0 2.3e-42 145.2 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK21652.1 - 6.3e-16 58.4 0.0 9.5e-16 57.9 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Sacchrp_dh_C PF16653.5 CRK21685.1 - 5.3e-30 105.4 0.0 6.5e-30 105.1 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain ADH_N PF08240.12 CRK21714.1 - 0.00015 21.6 1.3 0.00018 21.4 1.3 1.1 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Nop14 PF04147.12 CRK21715.1 - 3.2e-36 125.0 12.0 3.6e-36 124.8 12.0 1.0 1 0 0 1 1 1 1 Nop14-like family DUF2255 PF10012.9 CRK21715.1 - 0.021 14.9 1.0 0.027 14.6 1.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2255) RRM_1 PF00076.22 CRK21726.1 - 1.6e-36 124.0 1.9 4.7e-19 68.0 0.1 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CRK21726.1 - 0.0037 17.4 0.2 0.06 13.5 0.0 2.6 1 1 1 2 2 2 1 RNA recognition motif RRM_3 PF08777.11 CRK21726.1 - 0.0048 16.9 0.8 0.77 9.8 0.2 2.3 2 0 0 2 2 2 2 RNA binding motif OB_RNB PF08206.11 CRK21726.1 - 0.019 14.6 1.0 1.7 8.4 0.0 2.6 2 0 0 2 2 2 0 Ribonuclease B OB domain PhetRS_B1 PF18262.1 CRK21726.1 - 0.13 12.5 0.1 4.7 7.5 0.0 2.3 2 1 0 2 2 2 0 Phe-tRNA synthetase beta subunit B1 domain DHquinase_I PF01487.15 CRK21741.1 - 4e-46 158.1 0.0 5.4e-46 157.7 0.0 1.2 1 0 0 1 1 1 1 Type I 3-dehydroquinase Glyco_hydro_88 PF07470.13 CRK21743.1 - 6.7e-13 48.4 0.4 6.7e-13 48.4 0.4 1.5 2 0 0 2 2 2 1 Glycosyl Hydrolase Family 88 Glyco_hydro_88 PF07470.13 CRK21745.1 - 2.4e-15 56.4 0.2 1.8e-14 53.6 0.0 1.9 2 0 0 2 2 2 1 Glycosyl Hydrolase Family 88 Peptidase_S8 PF00082.22 CRK21747.1 - 1.6e-12 47.3 0.4 1.6e-12 47.3 0.4 1.7 2 0 0 2 2 2 1 Subtilase family WSC PF01822.19 CRK21747.1 - 0.00029 21.0 6.2 0.00058 20.0 3.4 2.8 2 1 0 2 2 2 1 WSC domain Atg14 PF10186.9 CRK21747.1 - 0.067 12.3 0.3 0.12 11.5 0.3 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2203 PF09969.9 CRK21747.1 - 0.071 13.8 0.2 0.17 12.6 0.2 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) ZapB PF06005.12 CRK21747.1 - 0.58 10.6 4.8 1.2 9.7 4.8 1.4 1 0 0 1 1 1 0 Cell division protein ZapB MFS_1 PF07690.16 CRK21749.1 - 4.2e-34 118.0 54.8 4.2e-34 118.0 54.8 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK21749.1 - 3e-12 46.2 13.5 3e-12 46.2 13.5 2.6 1 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 CRK21749.1 - 4.5e-09 35.3 19.1 7.7e-09 34.5 19.1 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2937 PF11157.8 CRK21749.1 - 0.54 9.9 3.0 0.34 10.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) OATP PF03137.20 CRK21749.1 - 2 6.6 11.6 0.095 11.0 3.1 2.4 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Oxidored_q6 PF01058.22 CRK21750.1 - 3.6e-22 78.6 0.1 5.1e-22 78.1 0.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit HECT PF00632.25 CRK21751.1 - 7.8e-69 232.5 0.0 1.1e-68 232.0 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 CRK21751.1 - 5.9e-33 112.6 25.3 6.2e-13 48.6 6.3 4.0 4 0 0 4 4 4 3 WW domain C2 PF00168.30 CRK21751.1 - 5e-18 65.3 0.0 1.7e-17 63.6 0.0 2.0 1 0 0 1 1 1 1 C2 domain TFIIA PF03153.13 CRK21751.1 - 0.066 13.2 9.5 0.097 12.6 9.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Rrn6 PF10214.9 CRK21751.1 - 0.079 11.4 9.9 0.11 10.9 9.9 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor RRM_1 PF00076.22 CRK21752.1 - 1.3e-16 60.2 0.0 2e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spc7 PF08317.11 CRK21752.1 - 0.015 14.2 2.5 0.018 13.9 2.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Nup35_RRM_2 PF14605.6 CRK21752.1 - 0.049 13.6 0.0 0.085 12.9 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF724 PF05266.14 CRK21752.1 - 0.08 12.8 2.9 0.11 12.3 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) RRM_occluded PF16842.5 CRK21752.1 - 0.16 11.8 0.0 0.31 10.9 0.0 1.5 1 1 0 1 1 1 0 Occluded RNA-recognition motif MGC-24 PF05283.11 CRK21753.1 - 0.044 14.2 9.4 0.057 13.9 9.4 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF1487 PF07368.11 CRK21753.1 - 0.11 11.9 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) CFEM PF05730.11 CRK21753.1 - 0.34 11.0 10.5 0.72 10.0 10.5 1.7 1 1 0 1 1 1 0 CFEM domain FSA_C PF10479.9 CRK21753.1 - 3.4 5.7 8.7 3.9 5.5 8.7 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Zn_clus PF00172.18 CRK21755.1 - 6e-07 29.5 9.9 1e-06 28.8 9.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 CRK21755.1 - 8e-06 24.9 0.2 1.9e-05 23.6 0.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Alba PF01918.21 CRK21756.1 - 0.00018 21.2 0.0 0.00032 20.5 0.0 1.3 1 0 0 1 1 1 1 Alba DUF202 PF02656.15 CRK21757.1 - 1.5e-16 60.6 4.8 9e-16 58.1 3.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Tctex-1 PF03645.13 CRK21758.1 - 7e-37 125.8 0.0 8.9e-37 125.5 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family F-box-like PF12937.7 CRK21759.1 - 0.0018 18.1 0.0 0.0037 17.1 0.0 1.5 1 0 0 1 1 1 1 F-box-like Pex14_N PF04695.13 CRK21759.1 - 0.46 11.1 9.0 8.1 7.1 0.1 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region p450 PF00067.22 CRK21761.1 - 5.3e-20 71.6 0.0 1.1e-18 67.2 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 SBP56 PF05694.11 CRK21762.1 - 1.5e-06 27.4 0.0 3.3e-05 22.9 0.0 2.6 1 1 0 1 1 1 1 56kDa selenium binding protein (SBP56) Cupin_1 PF00190.22 CRK21763.1 - 3.9e-40 136.9 0.1 4.8e-19 68.4 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 CRK21763.1 - 5.5e-23 80.5 1.5 1.7e-12 46.9 0.1 2.2 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 CRK21763.1 - 3.6e-05 23.4 0.0 0.11 12.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 CRK21763.1 - 0.0067 16.3 0.4 0.8 9.6 0.0 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain Cpn10 PF00166.21 CRK21763.1 - 0.11 12.5 0.0 2.5 8.2 0.0 2.3 2 0 0 2 2 2 0 Chaperonin 10 Kd subunit Auxin_BP PF02041.16 CRK21763.1 - 0.14 11.8 0.0 0.35 10.5 0.0 1.6 2 0 0 2 2 2 0 Auxin binding protein Gln-synt_N PF03951.19 CRK21764.1 - 5.3e-14 51.7 0.0 1.1e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Gln-synt_C PF00120.24 CRK21764.1 - 7.8e-14 51.4 0.0 2.7e-11 43.1 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain DUF2135 PF09906.9 CRK21769.1 - 0.025 14.9 0.2 0.052 13.8 0.2 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2135) eIF3_N PF09440.10 CRK21776.1 - 2.1e-36 125.3 1.7 2.4e-36 125.1 1.7 1.0 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain Caprin-1_dimer PF18293.1 CRK21776.1 - 0.0093 16.5 0.9 0.032 14.7 0.3 2.0 1 1 1 2 2 2 1 Caprin-1 dimerization domain Herpes_DNAp_acc PF04929.12 CRK21778.1 - 0.52 9.2 2.9 0.64 8.9 2.9 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Aminotran_3 PF00202.21 CRK21783.1 - 1.2e-08 34.1 0.0 1.5e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III PRT_C PF08372.10 CRK21783.1 - 0.03 14.1 0.0 0.044 13.5 0.0 1.2 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal SRI PF08236.11 CRK21786.1 - 2.1e-20 72.7 8.7 6.6e-20 71.1 8.7 1.9 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.28 CRK21786.1 - 4.7e-17 62.9 0.2 4.7e-17 62.9 0.2 4.0 3 2 0 3 3 3 1 SET domain AWS PF17907.1 CRK21786.1 - 1e-10 41.5 7.5 1e-10 41.5 7.5 2.5 2 0 0 2 2 2 1 AWS domain Med26 PF08711.11 CRK21786.1 - 5.9e-05 23.0 0.2 0.00018 21.4 0.1 2.0 2 0 0 2 2 2 1 TFIIS helical bundle-like domain WW PF00397.26 CRK21786.1 - 0.035 14.2 1.6 0.096 12.8 1.6 1.8 1 0 0 1 1 1 0 WW domain VIT1 PF01988.19 CRK21786.1 - 0.21 11.4 0.1 0.58 10.0 0.1 1.7 1 0 0 1 1 1 0 VIT family DUF2431 PF10354.9 CRK21787.1 - 3.1e-56 190.3 0.0 6e-56 189.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) ThiF PF00899.21 CRK21791.1 - 0.18 11.1 0.0 0.21 10.9 0.0 1.1 1 0 0 1 1 1 0 ThiF family Zwint PF15556.6 CRK21792.1 - 0.18 11.3 3.9 4.1 6.8 1.0 2.3 2 0 0 2 2 2 0 ZW10 interactor ALMT PF11744.8 CRK21792.1 - 0.37 9.6 1.8 0.6 8.9 1.8 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter ketoacyl-synt PF00109.26 CRK21795.1 - 5.4e-62 209.7 5.0 2.4e-61 207.5 0.3 2.2 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 CRK21795.1 - 1.9e-37 127.9 1.4 3.7e-37 126.9 1.4 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Ubiq_cyt_C_chap PF03981.12 CRK21795.1 - 3.2e-18 66.2 1.3 1.2e-17 64.3 1.4 1.9 2 0 0 2 2 2 1 Ubiquinol-cytochrome C chaperone Thiolase_N PF00108.23 CRK21795.1 - 3.3e-06 26.7 0.6 4.5e-05 23.0 0.1 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CRK21795.1 - 0.018 14.7 0.5 0.018 14.7 0.5 2.6 2 2 1 3 3 3 0 Thiolase, C-terminal domain DSBA PF01323.20 CRK21795.1 - 0.2 11.4 0.3 0.39 10.5 0.3 1.4 1 0 0 1 1 1 0 DSBA-like thioredoxin domain OPT PF03169.15 CRK21797.1 - 2.1e-180 601.4 48.3 2.5e-180 601.2 48.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Dioxygenase_C PF00775.21 CRK21797.1 - 7e-42 142.9 0.0 1.2e-41 142.2 0.0 1.4 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 CRK21797.1 - 4.5e-28 96.9 0.6 1.4e-27 95.3 0.1 2.1 2 0 0 2 2 2 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 CRK21797.1 - 0.004 17.4 0.0 0.015 15.5 0.0 2.0 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain Fungal_trans PF04082.18 CRK21799.1 - 5.9e-23 81.3 0.1 9.6e-23 80.6 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK21799.1 - 2.9e-07 30.5 12.4 6.7e-07 29.3 12.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CoA_transf_3 PF02515.17 CRK21802.1 - 5.9e-38 130.9 0.0 6.5e-34 117.6 0.0 2.2 2 0 0 2 2 2 2 CoA-transferase family III Biotin_lipoyl PF00364.22 CRK21804.1 - 2.4e-21 75.3 0.3 4.6e-21 74.4 0.3 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 CRK21804.1 - 3e-08 33.9 0.0 1.2e-07 32.0 0.0 2.0 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 CRK21804.1 - 0.00011 22.0 0.0 0.00055 19.7 0.0 2.1 2 0 0 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.6 CRK21804.1 - 0.046 14.4 0.3 0.56 10.9 0.0 2.4 1 1 1 2 2 2 0 HlyD family secretion protein ArenaCapSnatch PF17296.2 CRK21804.1 - 0.18 11.3 0.0 0.28 10.6 0.0 1.2 1 0 0 1 1 1 0 Arenavirus cap snatching domain MFS_1 PF07690.16 CRK21806.1 - 3.9e-13 49.0 25.4 3.9e-13 49.0 25.4 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily Luteo_Vpg PF01659.16 CRK21806.1 - 0.31 11.4 5.6 0.7 10.3 5.6 1.5 1 0 0 1 1 1 0 Luteovirus putative VPg genome linked protein DHFR_1 PF00186.19 CRK21808.1 - 6.6e-26 90.9 0.0 2.3e-25 89.1 0.0 1.9 1 1 0 1 1 1 1 Dihydrofolate reductase LRR_8 PF13855.6 CRK21811.1 - 2.1e-14 53.0 14.2 4.3e-07 29.6 2.4 3.2 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 CRK21811.1 - 1.7e-13 50.5 2.2 0.0058 17.0 0.2 3.6 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CRK21811.1 - 0.00011 22.3 5.6 40 5.3 0.2 6.0 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_9 PF14580.6 CRK21811.1 - 0.01 15.3 0.3 0.037 13.5 0.2 1.8 1 1 0 1 1 1 0 Leucine-rich repeat LRR_6 PF13516.6 CRK21811.1 - 0.042 13.9 12.8 2 8.7 0.1 5.1 4 1 1 5 5 5 0 Leucine Rich repeat zf-HC5HC2H_2 PF13832.6 CRK21813.1 - 1.4e-33 115.3 7.2 1.4e-33 115.3 7.2 2.5 2 0 0 2 2 2 1 PHD-zinc-finger like domain EPL1 PF10513.9 CRK21813.1 - 2.7e-30 105.8 0.1 4.9e-30 105.0 0.1 1.4 1 0 0 1 1 1 1 Enhancer of polycomb-like zf-HC5HC2H PF13771.6 CRK21813.1 - 3e-26 91.5 6.8 3e-26 91.5 6.8 2.7 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.6 CRK21813.1 - 3.1e-14 52.2 1.9 3.1e-14 52.2 1.9 2.4 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 CRK21813.1 - 5.1e-09 35.9 24.4 1.2e-08 34.7 9.5 2.7 2 0 0 2 2 2 2 PHD-finger zf-PHD-like PF15446.6 CRK21813.1 - 5 6.7 14.4 0.032 13.9 2.6 2.4 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain C1_2 PF03107.16 CRK21813.1 - 7.2 7.0 19.4 13 6.2 5.7 2.8 2 0 0 2 2 2 0 C1 domain zf-RING-like PF08746.11 CRK21813.1 - 7.3 7.0 21.4 0.058 13.7 6.0 2.6 2 0 0 2 2 2 0 RING-like domain Metallophos PF00149.28 CRK21815.1 - 4.3e-29 102.5 0.0 5.2e-29 102.2 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CRK21815.1 - 3.5e-23 81.8 0.9 5.8e-23 81.1 0.9 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain ARPC4 PF05856.12 CRK21824.1 - 1.2e-39 135.6 0.8 1.3e-39 135.5 0.8 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Citrate_synt PF00285.21 CRK21826.1 - 0.066 12.3 0.0 0.094 11.8 0.0 1.2 1 0 0 1 1 1 0 Citrate synthase, C-terminal domain Patatin PF01734.22 CRK21827.1 - 1.8e-06 28.3 0.0 2e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 Patatin-like phospholipase PIG-S PF10510.9 CRK21828.1 - 1.1e-34 120.1 0.0 1.3e-34 120.0 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Phage_P2_GpE PF06528.12 CRK21828.1 - 0.47 10.0 2.4 0.81 9.3 2.4 1.3 1 0 0 1 1 1 0 Phage P2 GpE DUF5060 PF16586.5 CRK21830.1 - 0.1 13.0 0.3 0.17 12.2 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5060) GnsAB_toxin PF08178.11 CRK21833.1 - 0.056 13.4 0.1 0.29 11.1 0.1 2.1 2 0 0 2 2 2 0 GnsA/GnsB toxin of bacterial toxin-antitoxin system ABC_tran_CTD PF16326.5 CRK21836.1 - 6.7e-05 23.1 4.1 6.7e-05 23.1 4.1 5.9 4 2 2 6 6 6 2 ABC transporter C-terminal domain IDEAL PF08858.10 CRK21836.1 - 0.013 15.3 0.9 0.07 12.9 0.9 2.4 1 0 0 1 1 1 0 IDEAL domain CorA PF01544.18 CRK21836.1 - 0.11 11.8 4.9 0.25 10.6 4.9 1.6 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF4239 PF14023.6 CRK21836.1 - 0.61 9.8 5.3 0.78 9.4 0.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4239) MAT1 PF06391.13 CRK21838.1 - 6.5 6.5 9.8 0.48 10.2 4.6 1.6 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 RNA_pol_Rpb5_N PF03871.14 CRK21839.1 - 1.9e-16 60.4 0.2 3.2e-16 59.7 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb5, N-terminal domain TFCD_C PF12612.8 CRK21840.1 - 1.1e-31 110.2 0.0 2.4e-31 109.1 0.0 1.6 1 0 0 1 1 1 1 Tubulin folding cofactor D C terminal HEAT PF02985.22 CRK21840.1 - 0.00084 19.4 3.5 0.24 11.8 0.0 5.4 5 0 0 5 5 5 1 HEAT repeat Methyltr_RsmB-F PF01189.17 CRK21841.1 - 6.7e-65 218.5 0.0 9.2e-25 87.5 0.0 4.8 4 0 0 4 4 4 4 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 CRK21841.1 - 0.00016 21.8 0.0 0.9 9.6 0.0 2.6 2 0 0 2 2 2 2 FtsJ-like methyltransferase DUF5497 PF17601.2 CRK21841.1 - 0.043 14.1 0.0 3.6 8.0 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5497) RrnaAD PF00398.20 CRK21841.1 - 0.12 11.4 0.0 16 4.5 0.0 2.2 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase ORC4_C PF14629.6 CRK21842.1 - 6.7e-68 228.3 0.0 1e-67 227.7 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 CRK21842.1 - 3.5e-12 47.0 0.0 1e-11 45.5 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain PHD PF00628.29 CRK21842.1 - 3e-11 43.0 8.6 5.4e-11 42.2 8.6 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 CRK21842.1 - 5.5e-11 41.8 3.3 1.2e-10 40.8 3.3 1.6 1 0 0 1 1 1 1 PHD-finger AAA PF00004.29 CRK21842.1 - 6.8e-10 39.5 0.1 1.8e-09 38.1 0.1 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CRK21842.1 - 6e-08 33.0 0.0 1.6e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 CRK21842.1 - 6.7e-07 29.5 0.0 1.4e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_19 PF13245.6 CRK21842.1 - 1.4e-05 25.5 0.0 4.2e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CRK21842.1 - 2.9e-05 24.1 0.1 0.00022 21.3 0.1 2.5 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 CRK21842.1 - 3e-05 24.0 0.0 0.00031 20.7 0.0 2.3 1 1 0 1 1 1 1 NACHT domain KAP_NTPase PF07693.14 CRK21842.1 - 0.00031 20.1 0.0 0.00053 19.3 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain TniB PF05621.11 CRK21842.1 - 0.0015 17.9 0.1 0.041 13.3 0.1 2.2 1 1 0 1 1 1 1 Bacterial TniB protein NB-ARC PF00931.22 CRK21842.1 - 0.0021 17.3 0.1 0.0039 16.4 0.1 1.3 1 0 0 1 1 1 1 NB-ARC domain DUF815 PF05673.13 CRK21842.1 - 0.0027 16.9 0.0 0.0047 16.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) zf-PHD-like PF15446.6 CRK21842.1 - 0.0036 16.9 1.9 0.0093 15.6 1.9 1.7 1 1 0 1 1 1 1 PHD/FYVE-zinc-finger like domain AAA_30 PF13604.6 CRK21842.1 - 0.0037 17.0 0.0 0.0082 15.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain FYVE_2 PF02318.16 CRK21842.1 - 0.0037 17.5 1.2 0.0076 16.5 1.2 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger C1_1 PF00130.22 CRK21842.1 - 0.0045 16.9 1.1 0.0045 16.9 1.1 1.6 2 0 0 2 2 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) ATP-synt_ab PF00006.25 CRK21842.1 - 0.0094 15.6 0.0 0.021 14.5 0.0 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_28 PF13521.6 CRK21842.1 - 0.013 15.8 0.4 0.4 10.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 CRK21842.1 - 0.015 14.6 0.0 0.033 13.6 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family ABC_tran PF00005.27 CRK21842.1 - 0.019 15.5 0.0 0.043 14.3 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_5 PF07728.14 CRK21842.1 - 0.027 14.5 0.0 0.088 12.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 CRK21842.1 - 0.028 14.6 0.0 0.11 12.6 0.0 2.1 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 CRK21842.1 - 0.028 14.1 0.2 0.11 12.3 0.2 1.9 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.6 CRK21842.1 - 0.041 13.6 0.0 0.088 12.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 CRK21842.1 - 0.046 13.2 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 CRK21842.1 - 0.065 13.8 0.0 0.2 12.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 CRK21842.1 - 0.072 12.1 0.2 0.18 10.8 0.0 1.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MobB PF03205.14 CRK21842.1 - 0.089 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B G-alpha PF00503.20 CRK21842.1 - 0.11 11.6 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_17 PF13207.6 CRK21842.1 - 0.11 12.9 0.0 0.54 10.7 0.0 2.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CRK21842.1 - 0.13 12.7 0.0 0.3 11.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Prok-RING_1 PF14446.6 CRK21842.1 - 0.14 12.1 5.1 0.31 11.0 5.1 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 TsaE PF02367.17 CRK21842.1 - 0.14 12.1 0.0 0.38 10.8 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE zf-RRPl_C4 PF17026.5 CRK21842.1 - 0.16 12.0 2.8 1.2 9.3 2.8 2.2 1 1 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type C1_2 PF03107.16 CRK21842.1 - 0.2 12.0 3.4 0.61 10.4 3.4 1.8 1 0 0 1 1 1 0 C1 domain zf-HC5HC2H PF13771.6 CRK21842.1 - 0.2 11.9 2.6 0.43 10.9 2.6 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain AT_hook PF02178.19 CRK21842.1 - 1.1 9.4 10.8 1.1 9.4 7.5 2.9 2 0 0 2 2 2 0 AT hook motif DZR PF12773.7 CRK21842.1 - 7.2 6.7 9.0 25 5.0 3.7 2.4 1 1 1 2 2 2 0 Double zinc ribbon TMEM51 PF15345.6 CRK21843.1 - 0.75 9.6 5.6 1.3 8.8 5.6 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 SOG2 PF10428.9 CRK21843.1 - 4.4 6.4 11.6 6.3 5.9 11.6 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein RGS PF00615.19 CRK21844.1 - 3.3e-76 253.2 0.3 1.6e-36 125.1 0.0 3.0 2 0 0 2 2 2 2 Regulator of G protein signaling domain DEP PF00610.21 CRK21844.1 - 4.3e-46 154.8 0.4 9.4e-19 67.2 0.1 6.2 6 0 0 6 6 6 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Replic_Relax PF13814.6 CRK21844.1 - 5.4e-08 33.1 0.4 0.64 10.0 0.0 4.8 4 0 0 4 4 4 2 Replication-relaxation NMT PF01233.19 CRK21844.1 - 0.0058 16.5 0.0 5.6 6.8 0.0 2.6 2 0 0 2 2 2 2 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain RGS-like PF09128.11 CRK21844.1 - 0.01 15.5 0.0 6.4 6.4 0.0 2.3 2 0 0 2 2 2 0 Regulator of G protein signalling-like domain HAT PF02184.16 CRK21844.1 - 0.1 12.6 2.5 1.1e+02 2.9 0.0 4.3 4 0 0 4 4 4 0 HAT (Half-A-TPR) repeat CENP-R PF06729.12 CRK21844.1 - 0.35 10.8 6.0 8.4 6.3 0.6 2.6 2 0 0 2 2 2 0 Kinetochore component, CENP-R GlyL_C PF12524.8 CRK21844.1 - 0.83 9.8 16.5 5.8 7.1 1.3 5.5 4 0 0 4 4 4 0 dsDNA virus glycoprotein L C terminal DNA_pol3_tau_4 PF12168.8 CRK21844.1 - 2.5 8.7 4.4 54 4.4 0.4 3.0 2 0 0 2 2 2 0 DNA polymerase III subunits tau domain IV DnaB-binding Lipoxygenase PF00305.19 CRK21845.1 - 0.12 10.7 0.0 0.17 10.3 0.0 1.1 1 0 0 1 1 1 0 Lipoxygenase Colicin_V PF02674.16 CRK21845.1 - 5.4 7.0 7.8 7.5 6.5 0.1 3.0 3 0 0 3 3 3 0 Colicin V production protein Lipoxygenase PF00305.19 CRK21846.1 - 0.16 10.3 0.0 0.24 9.8 0.0 1.1 1 0 0 1 1 1 0 Lipoxygenase RNA_pol_Rpb5_C PF01191.19 CRK21847.1 - 1.3e-54 182.0 0.9 1.4e-31 108.1 0.2 2.3 2 0 0 2 2 2 2 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 CRK21847.1 - 3.5e-28 98.0 0.0 2.8e-24 85.5 0.0 2.3 2 0 0 2 2 2 2 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 CRK21847.1 - 6.2e-08 32.7 0.0 0.025 14.6 0.0 2.9 3 0 0 3 3 3 2 Restriction endonuclease PSRT PF07636.11 CRK21847.1 - 0.036 13.7 1.1 1.3 8.8 0.1 2.5 2 0 0 2 2 2 0 PSRT Sof1 PF04158.14 CRK21847.1 - 0.065 13.5 0.8 17 5.8 0.1 2.3 2 0 0 2 2 2 0 Sof1-like domain Sld3_N PF18523.1 CRK21847.1 - 0.11 12.7 3.4 8.7 6.5 0.3 2.3 2 0 0 2 2 2 0 Sld3 N-terminal domain Peptidase_M7 PF02031.16 CRK21847.1 - 0.2 11.8 1.7 15 5.7 0.1 2.2 2 0 0 2 2 2 0 Streptomyces extracellular neutral proteinase (M7) family Occludin_ELL PF07303.13 CRK21848.1 - 0.022 15.5 1.7 0.022 15.5 1.7 2.5 1 1 0 2 2 2 0 Occludin homology domain Siva PF05458.12 CRK21848.1 - 1.3 8.6 3.6 17 5.0 0.3 2.1 1 1 1 2 2 2 0 Cd27 binding protein (Siva) DUF4239 PF14023.6 CRK21848.1 - 2.3 7.9 4.3 3.1 7.5 0.9 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF4239) DUF4407 PF14362.6 CRK21848.1 - 3 7.1 22.3 47 3.2 9.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) ABC_tran_CTD PF16326.5 CRK21848.1 - 4.6 7.6 15.2 0.22 11.8 0.9 3.8 2 2 2 4 4 4 0 ABC transporter C-terminal domain TFCD_C PF12612.8 CRK21849.1 - 6.1e-32 111.0 0.0 1.4e-31 109.9 0.0 1.7 1 0 0 1 1 1 1 Tubulin folding cofactor D C terminal HEAT PF02985.22 CRK21849.1 - 0.0058 16.8 0.5 0.2 12.0 0.1 3.7 3 0 0 3 3 3 1 HEAT repeat HEAT_EZ PF13513.6 CRK21849.1 - 0.53 10.9 3.8 3.1 8.4 0.1 4.4 4 0 0 4 4 4 0 HEAT-like repeat HEAT_2 PF13646.6 CRK21849.1 - 5.5 7.5 16.0 1 9.8 0.8 4.6 5 0 0 5 5 5 0 HEAT repeats ORC4_C PF14629.6 CRK21852.1 - 1.5e-49 168.3 0.0 3.5e-49 167.1 0.0 1.5 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 CRK21852.1 - 6.8e-12 46.1 0.1 2e-11 44.6 0.1 1.9 1 0 0 1 1 1 1 AAA ATPase domain PHD PF00628.29 CRK21852.1 - 4.1e-11 42.6 8.6 1e-10 41.3 8.6 1.7 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 CRK21852.1 - 7.7e-11 41.4 3.3 2.2e-10 39.9 3.3 1.9 1 0 0 1 1 1 1 PHD-finger AAA PF00004.29 CRK21852.1 - 1.8e-09 38.2 0.1 4.1e-09 37.0 0.1 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CRK21852.1 - 9.2e-08 32.5 0.0 2.3e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 CRK21852.1 - 2.5e-06 27.6 0.0 5e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_19 PF13245.6 CRK21852.1 - 2.2e-05 24.8 0.0 6e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CRK21852.1 - 4.4e-05 23.5 0.1 0.00045 20.2 0.0 2.5 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 CRK21852.1 - 5.4e-05 23.2 0.1 0.00051 20.0 0.1 2.4 1 1 0 1 1 1 1 NACHT domain KAP_NTPase PF07693.14 CRK21852.1 - 0.0015 17.8 0.0 0.0028 17.0 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain NB-ARC PF00931.22 CRK21852.1 - 0.0016 17.7 0.1 0.003 16.8 0.1 1.3 1 0 0 1 1 1 1 NB-ARC domain DUF815 PF05673.13 CRK21852.1 - 0.0047 16.1 0.0 0.0083 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) FYVE_2 PF02318.16 CRK21852.1 - 0.0062 16.8 1.8 0.016 15.4 1.8 1.6 1 0 0 1 1 1 1 FYVE-type zinc finger TniB PF05621.11 CRK21852.1 - 0.0066 15.9 0.1 0.14 11.5 0.1 2.3 1 1 0 1 1 1 1 Bacterial TniB protein AAA_30 PF13604.6 CRK21852.1 - 0.008 15.9 0.1 0.016 14.9 0.1 1.4 1 0 0 1 1 1 1 AAA domain C1_1 PF00130.22 CRK21852.1 - 0.0085 16.0 1.1 0.0085 16.0 1.1 2.1 2 0 0 2 2 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-PHD-like PF15446.6 CRK21852.1 - 0.014 15.1 2.7 0.032 13.9 2.7 1.6 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain ATP-synt_ab PF00006.25 CRK21852.1 - 0.018 14.7 0.0 0.038 13.6 0.0 1.5 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain PduV-EutP PF10662.9 CRK21852.1 - 0.034 13.9 0.1 0.08 12.7 0.1 1.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation FtsK_SpoIIIE PF01580.18 CRK21852.1 - 0.041 13.2 0.0 0.1 12.0 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family ABC_tran PF00005.27 CRK21852.1 - 0.042 14.4 0.0 0.091 13.3 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 CRK21852.1 - 0.075 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 CRK21852.1 - 0.077 13.0 0.0 0.24 11.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 CRK21852.1 - 0.079 13.2 0.4 0.88 9.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CRK21852.1 - 0.089 12.3 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 CRK21852.1 - 0.12 12.6 0.0 0.36 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain MeaB PF03308.16 CRK21852.1 - 0.17 10.9 0.0 0.32 10.0 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 CRK21852.1 - 0.17 12.4 0.0 0.41 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 CRK21852.1 - 0.17 11.7 0.0 0.37 10.7 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Prok-RING_1 PF14446.6 CRK21852.1 - 0.23 11.4 5.1 0.58 10.1 5.1 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 C1_2 PF03107.16 CRK21852.1 - 0.33 11.3 3.5 1.2 9.5 3.5 2.0 1 0 0 1 1 1 0 C1 domain zf-RRPl_C4 PF17026.5 CRK21852.1 - 0.34 11.0 2.5 1.7 8.8 2.5 2.1 1 1 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-HC5HC2H PF13771.6 CRK21852.1 - 0.34 11.2 3.5 1 9.6 3.5 1.8 1 0 0 1 1 1 0 PHD-like zinc-binding domain AT_hook PF02178.19 CRK21852.1 - 2.6 8.2 10.8 2 8.6 7.5 2.8 2 0 0 2 2 1 0 AT hook motif Glyco_hydro_2_N PF02837.18 CRK21855.1 - 5e-14 52.6 0.1 1.5e-13 51.0 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.17 CRK21855.1 - 4.3e-09 35.9 0.0 1.1e-08 34.6 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.21 CRK21855.1 - 1.1e-07 32.5 0.0 1.9e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Zn_clus PF00172.18 CRK21855.1 - 3.6e-06 27.0 4.2 7.7e-06 25.9 4.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BetaGal_dom4_5 PF13364.6 CRK21855.1 - 0.0014 19.1 0.0 0.0029 18.2 0.0 1.4 1 0 0 1 1 1 1 Beta-galactosidase jelly roll domain Fungal_trans_2 PF11951.8 CRK21855.1 - 0.047 12.5 0.0 0.087 11.6 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain SH3_9 PF14604.6 CRK21858.1 - 5.5e-08 32.5 3.2 3.9e-05 23.4 0.3 2.9 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.17 CRK21858.1 - 0.023 14.4 0.6 0.023 14.4 0.6 1.9 2 0 0 2 2 2 0 Variant SH3 domain Rpp20 PF12328.8 CRK21860.1 - 3.4e-29 101.5 0.3 4.9e-29 101.0 0.3 1.2 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 CRK21860.1 - 8.3e-13 48.0 0.0 1.6e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Alba Rogdi_lz PF10259.9 CRK21862.1 - 4e-89 298.6 0.0 4.5e-89 298.5 0.0 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein NIPSNAP PF07978.13 CRK21863.1 - 1.1e-41 141.2 2.0 1.3e-30 105.6 0.2 2.5 2 0 0 2 2 2 2 NIPSNAP FSH1 PF03959.13 CRK21866.1 - 5.7e-59 199.3 0.0 7.3e-59 199.0 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 CRK21866.1 - 0.0029 16.9 0.3 0.11 11.7 0.0 2.4 2 1 0 3 3 3 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CRK21866.1 - 0.06 13.0 0.0 3 7.4 0.1 2.3 1 1 1 2 2 2 0 alpha/beta hydrolase fold PE-PPE PF08237.11 CRK21866.1 - 0.066 12.8 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 PE-PPE domain Esterase PF00756.20 CRK21866.1 - 0.16 11.6 0.5 3.4 7.2 0.2 2.1 2 0 0 2 2 2 0 Putative esterase PCI PF01399.27 CRK21868.1 - 3.6e-22 78.8 0.1 1.8e-21 76.6 0.0 2.3 2 0 0 2 2 2 1 PCI domain RPN5_C PF18098.1 CRK21868.1 - 3.2e-16 59.1 1.1 8.8e-16 57.7 1.1 1.8 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain CAP PF00188.26 CRK21872.1 - 2.2e-14 54.4 2.9 3.1e-14 53.9 2.9 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family TonB_N PF16031.5 CRK21872.1 - 0.0024 18.4 29.4 0.0042 17.6 29.4 1.4 1 0 0 1 1 1 1 TonB polyproline region DUF2868 PF11067.8 CRK21872.1 - 0.21 11.1 2.2 0.32 10.5 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) PRCC PF10253.9 CRK21872.1 - 0.39 11.5 5.9 0.47 11.2 5.9 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting CHCH PF06747.13 CRK21878.1 - 5.3e-05 23.2 4.4 7.5e-05 22.8 4.4 1.2 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 CRK21878.1 - 0.0057 16.6 3.1 0.0078 16.2 3.1 1.2 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, DnaT PF17948.1 CRK21878.1 - 0.054 13.2 0.0 2.4 7.9 0.0 2.1 2 0 0 2 2 2 0 DnaT DNA-binding domain SBE2 PF17076.5 CRK21878.1 - 0.073 11.3 0.2 0.085 11.1 0.2 1.0 1 0 0 1 1 1 0 SBE2, cell-wall formation Nup54 PF13874.6 CRK21880.1 - 2.4e-37 128.1 0.2 2.4e-37 128.1 0.2 3.4 4 0 0 4 4 4 1 Nucleoporin complex subunit 54 Nup54_57_C PF18570.1 CRK21880.1 - 2.7e-15 55.7 8.0 5.2e-15 54.7 8.0 1.5 1 0 0 1 1 1 1 NUP57/Nup54 C-terminal domain DivIVA PF05103.13 CRK21880.1 - 0.021 14.9 0.6 0.021 14.9 0.6 2.6 3 1 0 3 3 3 0 DivIVA protein Ndc1_Nup PF09531.10 CRK21880.1 - 2.3 6.8 12.7 0.33 9.6 8.9 1.5 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 CRK21880.1 - 2.4 6.8 8.1 3.6 6.3 8.1 1.2 1 0 0 1 1 1 0 Presenilin GREB1 PF15782.5 CRK21880.1 - 6.8 3.7 12.4 9 3.3 12.4 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Lin-8 PF03353.15 CRK21880.1 - 9.8 5.6 18.6 2.7 7.5 14.7 1.8 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Tom5 PF10642.9 CRK21883.1 - 5.3e-23 80.8 0.5 5.8e-23 80.7 0.5 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase GDC-P PF02347.16 CRK21884.1 - 7.3e-76 255.7 0.3 1.4e-60 205.4 0.1 3.3 2 2 1 3 3 3 3 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 CRK21884.1 - 5e-07 29.3 0.0 9.5e-07 28.4 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 CRK21884.1 - 0.014 14.7 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Fasciclin PF02469.22 CRK21887.1 - 3.1e-42 143.8 0.0 6.8e-26 91.0 0.0 2.1 2 0 0 2 2 2 2 Fasciclin domain Glyco_hydro_16 PF00722.21 CRK21890.1 - 2.8e-15 56.2 1.4 4.6e-15 55.5 1.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 TaqI_C PF12950.7 CRK21890.1 - 0.14 12.2 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 TaqI-like C-terminal specificity domain Glyco_trans_2_3 PF13632.6 CRK21893.1 - 5.7e-50 170.0 8.5 5.7e-50 170.0 8.5 2.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 CRK21893.1 - 3.8e-06 26.8 0.0 1e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 CRK21893.1 - 0.00055 19.5 0.0 0.0012 18.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 CRK21893.1 - 0.0029 17.5 0.0 0.0056 16.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 ABC_tran PF00005.27 CRK21895.1 - 8e-48 162.4 0.1 6.7e-26 91.4 0.0 4.3 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CRK21895.1 - 4e-15 56.4 0.5 0.0022 17.9 0.1 4.6 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CRK21895.1 - 7.2e-12 45.2 0.1 0.0021 17.6 0.0 4.2 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CRK21895.1 - 2.5e-10 41.2 0.5 4.3e-05 24.1 0.0 3.3 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 CRK21895.1 - 4.5e-08 33.2 0.0 0.0046 17.0 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CRK21895.1 - 4.5e-07 29.9 0.1 0.0033 17.4 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 CRK21895.1 - 7e-07 28.9 0.7 0.0076 16.0 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 CRK21895.1 - 7.6e-05 23.0 0.2 0.85 9.9 0.0 3.3 2 1 0 2 2 2 2 AAA domain Chromo PF00385.24 CRK21895.1 - 0.00013 21.8 2.1 0.00013 21.8 2.1 2.1 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_15 PF13175.6 CRK21895.1 - 0.0002 21.2 0.1 0.22 11.2 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_28 PF13521.6 CRK21895.1 - 0.00054 20.2 0.0 0.045 14.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CRK21895.1 - 0.00097 19.7 0.0 0.56 10.8 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CRK21895.1 - 0.0025 18.0 0.0 3.2 7.9 0.0 3.0 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 CRK21895.1 - 0.004 17.1 0.1 1.5 8.7 0.0 2.6 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.22 CRK21895.1 - 0.0042 17.5 0.1 4.9 7.6 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA PF00004.29 CRK21895.1 - 0.0057 17.1 0.0 7.8 6.9 0.0 3.3 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_13 PF13166.6 CRK21895.1 - 0.0098 14.6 0.3 2 7.0 0.0 2.7 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.17 CRK21895.1 - 0.011 15.9 3.1 0.58 10.2 0.1 3.2 4 0 0 4 4 2 0 Helicase HerA, central domain AAA_24 PF13479.6 CRK21895.1 - 0.011 15.4 0.7 0.74 9.5 0.2 2.7 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 CRK21895.1 - 0.012 15.6 0.0 7.6 6.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 CRK21895.1 - 0.013 14.5 0.4 2.2 7.2 0.1 2.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SbcCD_C PF13558.6 CRK21895.1 - 0.014 15.6 0.7 5.1 7.4 0.0 3.6 3 1 0 3 3 2 0 Putative exonuclease SbcCD, C subunit Septin PF00735.18 CRK21895.1 - 0.019 14.3 0.0 3.8 6.7 0.0 2.5 2 0 0 2 2 2 0 Septin PduV-EutP PF10662.9 CRK21895.1 - 0.027 14.2 0.0 1.1 9.0 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.6 CRK21895.1 - 0.028 14.2 0.6 6.6 6.4 0.1 2.9 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 CRK21895.1 - 0.038 13.6 0.6 9.3 5.8 0.0 2.8 3 0 0 3 3 2 0 AAA domain Dynamin_N PF00350.23 CRK21895.1 - 0.04 14.0 1.5 0.53 10.3 0.0 3.2 4 0 0 4 4 3 0 Dynamin family AAA_16 PF13191.6 CRK21895.1 - 0.041 14.3 0.0 3.3 8.0 0.0 3.0 2 0 0 2 2 2 0 AAA ATPase domain DUF3584 PF12128.8 CRK21895.1 - 0.042 11.4 0.7 4.1 4.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) DUF1761 PF08570.10 CRK21895.1 - 0.046 14.0 0.6 0.11 12.7 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1761) Roc PF08477.13 CRK21895.1 - 0.051 13.8 0.0 7.1 6.9 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 CRK21895.1 - 0.056 12.6 0.1 3.5 6.7 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain DUF815 PF05673.13 CRK21895.1 - 0.073 12.2 0.0 4.7 6.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Ureide_permease PF07168.11 CRK21895.1 - 0.12 11.2 0.0 0.5 9.1 0.0 1.8 2 0 0 2 2 2 0 Ureide permease MadM PF03818.13 CRK21895.1 - 0.14 12.0 0.0 0.91 9.4 0.0 2.2 2 0 0 2 2 2 0 Malonate/sodium symporter MadM subunit ALF PF03752.13 CRK21895.1 - 0.19 11.7 1.1 26 4.9 0.0 2.7 2 0 0 2 2 2 0 Short repeats of unknown function TsaE PF02367.17 CRK21895.1 - 0.21 11.6 0.5 26 4.9 0.1 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SR-25 PF10500.9 CRK21895.1 - 9.7 5.7 17.1 0.014 15.0 3.9 2.2 2 0 0 2 2 1 0 Nuclear RNA-splicing-associated protein DUF1244 PF06844.11 CRK21897.1 - 0.1 12.8 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1244) Orthopox_C10L PF07020.11 CRK21897.1 - 0.55 11.0 6.5 1.3 9.8 6.5 1.6 1 0 0 1 1 1 0 Orthopoxvirus C10L protein Glyco_hydro_3_C PF01915.22 CRK21900.1 - 1.6e-41 142.5 0.0 2.7e-41 141.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 CRK21900.1 - 1.6e-37 129.6 0.0 2.7e-37 128.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 CRK21900.1 - 1.3e-20 73.3 0.1 2.8e-20 72.2 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain MFS_1 PF07690.16 CRK21902.1 - 3.7e-30 105.0 26.7 5.4e-30 104.5 26.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_88 PF07470.13 CRK21905.1 - 1.7e-92 310.1 3.9 2e-92 309.9 3.9 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_hydro_127 PF07944.12 CRK21905.1 - 0.0014 17.2 0.6 0.002 16.7 0.6 1.1 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 Glyco_hydro_76 PF03663.14 CRK21905.1 - 0.23 11.0 7.2 0.098 12.2 0.7 2.9 1 1 2 3 3 3 0 Glycosyl hydrolase family 76 MFS_1 PF07690.16 CRK21907.1 - 1.7e-22 79.8 20.1 4.8e-21 75.1 1.7 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1179 PF06678.11 CRK21907.1 - 0.024 14.6 0.2 0.045 13.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1179) MotA_ExbB PF01618.16 CRK21907.1 - 0.83 9.4 2.4 1.2 8.9 1.0 2.0 2 0 0 2 2 2 0 MotA/TolQ/ExbB proton channel family Glyco_hydro_61 PF03443.14 CRK21909.1 - 1.2e-50 172.3 0.0 2.1e-50 171.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 TPR_12 PF13424.6 CRK21909.1 - 0.0007 19.8 1.0 0.0024 18.1 0.6 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 CRK21909.1 - 0.0014 18.5 0.3 0.035 14.1 0.2 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat Helo_like_N PF17111.5 CRK21909.1 - 0.0015 17.9 0.9 0.0015 17.9 0.9 1.8 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins TPR_4 PF07721.14 CRK21909.1 - 0.0059 17.1 1.6 0.0059 17.1 1.6 3.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_MalT PF17874.1 CRK21909.1 - 0.011 15.1 1.0 0.047 13.1 0.9 1.9 2 0 0 2 2 2 0 MalT-like TPR region TPR_19 PF14559.6 CRK21909.1 - 0.014 15.9 2.0 0.18 12.3 0.8 2.9 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 CRK21909.1 - 0.032 14.1 0.1 0.3 11.0 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Astro_capsid_p PF12226.8 CRK21909.1 - 0.045 12.9 2.1 0.073 12.2 2.1 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein TPR_10 PF13374.6 CRK21909.1 - 0.13 12.1 0.1 0.36 10.8 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Baculo_F PF12259.8 CRK21909.1 - 0.19 10.2 0.1 0.3 9.6 0.1 1.2 1 0 0 1 1 1 0 Baculovirus F protein TPR_2 PF07719.17 CRK21909.1 - 0.2 11.9 8.4 0.17 12.1 0.3 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 CRK21909.1 - 0.38 11.7 5.0 0.31 12.0 0.2 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 CRK21909.1 - 0.97 10.2 3.9 26 5.7 0.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Sugar_tr PF00083.24 CRK21912.1 - 5.3e-78 262.9 7.9 5.3e-78 262.9 7.9 3.2 4 0 0 4 4 2 1 Sugar (and other) transporter ABC2_membrane PF01061.24 CRK21912.1 - 6.3e-69 231.6 44.8 5.4e-41 140.3 14.3 3.8 5 0 0 5 5 3 2 ABC-2 type transporter PDR_CDR PF06422.12 CRK21912.1 - 6.7e-38 128.5 0.4 3.9e-31 106.8 0.0 3.1 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.27 CRK21912.1 - 2.2e-24 86.5 0.0 4.1e-12 46.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter Pec_lyase_C PF00544.19 CRK21912.1 - 1.2e-22 80.5 8.6 4.2e-22 78.8 8.6 1.8 1 1 0 1 1 1 1 Pectate lyase MFS_1 PF07690.16 CRK21912.1 - 3e-14 52.7 15.5 3e-14 52.7 15.5 5.8 5 1 0 5 5 4 1 Major Facilitator Superfamily ABC_trans_N PF14510.6 CRK21912.1 - 3.9e-14 53.0 1.6 1.2e-13 51.4 0.0 2.7 2 0 0 2 2 2 1 ABC-transporter N-terminal AAA_29 PF13555.6 CRK21912.1 - 1.6e-06 27.7 1.2 0.00057 19.6 0.3 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain Beta_helix PF13229.6 CRK21912.1 - 8.5e-06 25.7 12.0 0.00023 21.1 6.8 2.3 1 1 1 2 2 2 2 Right handed beta helix region AAA_25 PF13481.6 CRK21912.1 - 1.4e-05 24.8 0.5 5.4e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CRK21912.1 - 3.1e-05 24.2 0.1 0.044 13.9 0.1 2.8 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 CRK21912.1 - 0.00011 22.8 0.0 0.04 14.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 CRK21912.1 - 0.00018 21.4 0.0 0.0017 18.2 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 CRK21912.1 - 0.00023 21.6 0.0 0.15 12.4 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain Pectate_lyase_3 PF12708.7 CRK21912.1 - 0.013 15.4 3.4 0.015 15.1 2.1 1.7 1 1 0 1 1 1 0 Pectate lyase superfamily protein NosD PF05048.13 CRK21912.1 - 0.013 14.8 2.5 0.027 13.7 2.5 1.4 1 0 0 1 1 1 0 Periplasmic copper-binding protein (NosD) NACHT PF05729.12 CRK21912.1 - 0.027 14.4 0.1 0.46 10.4 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA_22 PF13401.6 CRK21912.1 - 0.035 14.4 0.2 4.4 7.6 0.1 2.7 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 CRK21912.1 - 0.062 13.2 0.0 0.7 9.8 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_23 PF13476.6 CRK21912.1 - 0.066 13.7 0.1 0.15 12.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 CRK21912.1 - 0.16 11.7 0.0 0.5 10.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_24 PF13479.6 CRK21912.1 - 0.21 11.3 0.9 8.8 6.0 0.2 2.7 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 CRK21912.1 - 0.42 10.9 3.6 0.79 10.0 0.9 2.4 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 CRK21912.1 - 1.1 8.8 5.1 0.91 9.1 1.2 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF4834 PF16118.5 CRK21912.1 - 1.5 9.9 3.3 1.4e+02 3.6 0.0 4.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) DLH PF01738.18 CRK21913.1 - 6.5e-18 65.1 0.1 5.8e-17 62.0 0.1 2.3 1 1 0 1 1 1 1 Dienelactone hydrolase family Fungal_trans_2 PF11951.8 CRK21914.1 - 1.8e-16 59.9 0.0 5.1e-16 58.5 0.0 1.6 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK21914.1 - 0.00016 21.7 11.8 0.00031 20.8 11.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Romo1 PF10247.9 CRK21916.1 - 7.2e-29 100.0 13.3 1.1e-28 99.4 13.3 1.3 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.19 CRK21916.1 - 0.0099 16.2 2.3 0.015 15.7 2.3 1.4 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family FHA PF00498.26 CRK21917.1 - 7.6e-16 58.2 0.3 2.6e-15 56.5 0.0 2.1 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 CRK21917.1 - 0.0023 18.2 0.0 0.0058 16.9 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain YhfZ_C PF14503.6 CRK21917.1 - 0.13 11.8 0.0 0.13 11.8 0.0 1.8 2 0 0 2 2 2 0 YhfZ C-terminal domain CCDC144C PF14915.6 CRK21917.1 - 0.43 9.6 13.5 0.25 10.4 4.2 2.1 2 0 0 2 2 2 0 CCDC144C protein coiled-coil region Vps51 PF08700.11 CRK21917.1 - 0.52 10.4 5.7 10 6.3 0.3 2.7 2 0 0 2 2 2 0 Vps51/Vps67 DUF3584 PF12128.8 CRK21917.1 - 0.69 7.4 17.9 0.97 6.9 17.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Fib_alpha PF08702.10 CRK21917.1 - 0.75 10.0 3.9 17 5.5 0.5 2.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family GAS PF13851.6 CRK21917.1 - 0.84 8.9 16.4 0.21 10.9 6.5 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Uds1 PF15456.6 CRK21917.1 - 2.4 8.3 17.3 0.14 12.4 7.4 2.8 1 1 1 2 2 2 0 Up-regulated During Septation XhlA PF10779.9 CRK21917.1 - 4.1 7.7 10.6 2.6 8.3 0.6 2.5 2 0 0 2 2 2 0 Haemolysin XhlA Sec34 PF04136.15 CRK21917.1 - 5.7 6.8 9.0 5.1 7.0 1.3 2.2 2 0 0 2 2 2 0 Sec34-like family DUF4047 PF13256.6 CRK21917.1 - 6.3 7.0 6.2 0.8 9.9 1.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) Sec8_exocyst PF04048.14 CRK21917.1 - 7.3 6.5 6.5 6.2 6.7 0.8 2.2 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain Glycophorin_A PF01102.18 CRK21918.1 - 0.12 12.6 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 Glycophorin A PAP_assoc PF03828.19 CRK21920.1 - 1.2e-16 60.7 0.1 2.7e-16 59.5 0.1 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 CRK21920.1 - 5.9e-06 26.5 0.0 1.1e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 CRK21920.1 - 0.029 14.5 0.0 0.055 13.6 0.0 1.5 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase DUF3105 PF11303.8 CRK21921.1 - 0.0012 19.0 0.6 0.0016 18.6 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3105) AhpC-TSA_2 PF13911.6 CRK21922.1 - 0.0012 18.9 0.1 0.002 18.3 0.1 1.3 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme CALM_bind PF16025.5 CRK21924.1 - 1 9.9 11.6 1.6 9.2 6.9 2.4 2 0 0 2 2 2 0 Calcium-dependent calmodulin binding baeRF_family12 PF18856.1 CRK21924.1 - 2.5 8.7 5.5 6.5 7.3 2.5 2.2 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 12 SLC35F PF06027.12 CRK21925.1 - 1.5e-69 234.8 17.7 1.2e-49 169.5 9.8 2.2 1 1 1 2 2 2 2 Solute carrier family 35 EamA PF00892.20 CRK21925.1 - 6e-05 23.2 14.4 6e-05 23.2 14.4 2.3 2 1 1 3 3 3 1 EamA-like transporter family FUSC-like PF12805.7 CRK21925.1 - 0.025 13.7 1.6 0.29 10.2 0.0 2.2 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS DUF2516 PF10724.9 CRK21925.1 - 4.1 7.8 8.8 3.4 8.0 2.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2516) Metallophos PF00149.28 CRK21927.1 - 2.4e-09 38.0 1.0 5.1e-09 36.9 1.0 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Sugar_tr PF00083.24 CRK21928.1 - 1.4e-64 218.7 9.0 1.7e-64 218.3 9.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter 2-Hacid_dh_C PF02826.19 CRK21928.1 - 3.9e-35 120.8 0.0 8.2e-35 119.8 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MFS_1 PF07690.16 CRK21928.1 - 1e-14 54.3 17.5 1e-14 54.3 17.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily 2-Hacid_dh PF00389.30 CRK21928.1 - 8e-07 28.8 0.0 1.5e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain HTH_1 PF00126.27 CRK21928.1 - 0.13 12.2 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family Amidase PF01425.21 CRK21929.1 - 7.8e-116 387.7 0.1 1e-115 387.3 0.1 1.2 1 0 0 1 1 1 1 Amidase CBFD_NFYB_HMF PF00808.23 CRK21931.1 - 1.2e-17 64.0 0.7 1.2e-17 64.0 0.7 1.8 2 1 1 3 3 3 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CRK21931.1 - 2e-05 25.0 0.2 0.00011 22.6 0.0 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 CRK21931.1 - 0.026 14.5 0.4 0.077 13.0 0.0 1.9 2 1 0 2 2 2 0 Bromodomain associated BBIP10 PF14777.6 CRK21931.1 - 0.07 12.7 0.7 0.7 9.5 0.1 2.5 2 1 0 2 2 2 0 Cilia BBSome complex subunit 10 DAO PF01266.24 CRK21932.1 - 5.8e-49 167.6 1.3 6.5e-49 167.4 1.3 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CRK21932.1 - 0.021 15.1 0.0 0.051 13.8 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CRK21932.1 - 0.035 13.3 0.0 3.1 6.9 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CRK21932.1 - 0.052 14.1 0.0 0.43 11.2 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase UPF0561 PF10573.9 CRK21933.1 - 0.016 15.3 2.5 0.9 9.7 0.1 2.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0561 Mab-21 PF03281.14 CRK21933.1 - 0.067 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Mab-21 protein COX16 PF14138.6 CRK21934.1 - 5.5e-35 119.7 0.2 8.2e-35 119.2 0.2 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 zf-P11 PF03854.14 CRK21935.1 - 0.17 11.6 0.0 0.36 10.5 0.0 1.4 1 0 0 1 1 1 0 P-11 zinc finger EF-hand_14 PF17959.1 CRK21935.1 - 0.23 11.8 5.2 9.6 6.6 0.2 2.8 2 0 0 2 2 2 0 EF-hand domain Abhydrolase_2 PF02230.16 CRK21936.1 - 9.6e-58 195.5 0.0 1.1e-57 195.3 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 CRK21936.1 - 1.4e-08 34.4 0.6 4e-05 23.0 0.0 3.0 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 CRK21936.1 - 3.3e-05 23.9 0.1 0.22 11.3 0.0 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CRK21936.1 - 0.0016 18.0 1.1 0.078 12.4 0.0 2.4 3 0 0 3 3 3 1 Prolyl oligopeptidase family DLH PF01738.18 CRK21936.1 - 0.0042 16.7 0.0 0.0076 15.8 0.0 1.4 1 1 0 1 1 1 1 Dienelactone hydrolase family FSH1 PF03959.13 CRK21936.1 - 0.009 15.7 0.0 3.5 7.2 0.1 2.3 2 1 0 2 2 2 2 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 CRK21936.1 - 0.0095 16.6 6.5 0.027 15.1 6.5 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2920 PF11144.8 CRK21936.1 - 0.012 14.8 0.0 0.85 8.7 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2920) Abhydrolase_1 PF00561.20 CRK21936.1 - 0.019 14.6 0.7 1.1 8.8 0.1 2.7 2 1 1 3 3 3 0 alpha/beta hydrolase fold DUF2974 PF11187.8 CRK21936.1 - 0.052 13.1 0.1 0.08 12.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Esterase PF00756.20 CRK21936.1 - 0.064 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Cutinase PF01083.22 CRK21936.1 - 0.21 11.5 0.0 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 Cutinase IMD PF08397.11 CRK21937.1 - 4.1e-05 23.1 1.2 0.0016 17.9 0.1 2.3 2 0 0 2 2 2 2 IRSp53/MIM homology domain Abhydrolase_2 PF02230.16 CRK21938.1 - 2e-58 197.8 0.0 2.3e-58 197.5 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 CRK21938.1 - 6.3e-08 32.2 0.4 0.00031 20.1 0.0 3.0 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 CRK21938.1 - 3.2e-05 23.9 0.1 0.3 10.9 0.2 2.5 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CRK21938.1 - 0.0016 19.1 3.9 0.0039 17.8 3.9 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 CRK21938.1 - 0.0022 17.6 0.0 0.0041 16.7 0.0 1.4 1 1 0 1 1 1 1 Dienelactone hydrolase family DUF2920 PF11144.8 CRK21938.1 - 0.0051 16.0 0.0 0.32 10.1 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF2920) Peptidase_S9 PF00326.21 CRK21938.1 - 0.0057 16.1 0.6 0.41 10.1 0.0 2.5 3 0 0 3 3 3 1 Prolyl oligopeptidase family FSH1 PF03959.13 CRK21938.1 - 0.011 15.4 0.0 0.29 10.8 0.0 2.3 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 CRK21938.1 - 0.016 14.9 1.3 1.2 8.8 0.2 3.0 2 2 1 3 3 3 0 alpha/beta hydrolase fold Esterase PF00756.20 CRK21938.1 - 0.02 14.6 0.0 0.039 13.6 0.0 1.5 2 0 0 2 2 2 0 Putative esterase DUF2974 PF11187.8 CRK21938.1 - 0.045 13.3 0.0 0.059 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Cutinase PF01083.22 CRK21938.1 - 0.25 11.3 0.0 0.4 10.6 0.0 1.4 1 0 0 1 1 1 0 Cutinase IMD PF08397.11 CRK21939.1 - 4.3e-06 26.3 1.2 0.0016 17.9 0.1 2.2 2 0 0 2 2 2 2 IRSp53/MIM homology domain Fungal_trans PF04082.18 CRK21940.1 - 8.8e-30 103.6 0.2 1.3e-29 103.1 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK21940.1 - 0.0033 17.5 6.7 0.016 15.3 0.4 2.6 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain PSRT PF07636.11 CRK21940.1 - 4 7.2 10.1 1.1 9.0 4.5 2.9 3 0 0 3 3 3 0 PSRT COesterase PF00135.28 CRK21941.1 - 3.6e-93 313.2 0.0 4.7e-93 312.8 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CRK21941.1 - 0.0069 16.3 0.0 0.014 15.2 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CRK21941.1 - 0.093 12.2 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Fungal_trans PF04082.18 CRK21942.1 - 5.8e-11 41.9 0.2 2.3e-10 40.0 0.0 1.8 1 1 1 2 2 2 1 Fungal specific transcription factor domain Abhydrolase_1 PF00561.20 CRK21943.1 - 4.8e-47 160.8 0.0 4.5e-44 151.0 0.0 3.1 2 2 0 2 2 2 2 alpha/beta hydrolase fold Esterase PF00756.20 CRK21943.1 - 0.00093 18.9 0.0 0.0016 18.1 0.0 1.3 1 0 0 1 1 1 1 Putative esterase zf-RING_6 PF14835.6 CRK21943.1 - 0.16 11.8 0.2 0.4 10.6 0.2 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Abhydrolase_2 PF02230.16 CRK21943.1 - 0.26 11.1 0.2 1.8 8.4 0.0 1.9 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase NUDIX PF00293.28 CRK21945.1 - 0.00011 22.3 0.0 0.00019 21.5 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Involucrin_N PF10583.9 CRK21945.1 - 0.043 14.4 0.0 0.098 13.3 0.0 1.5 1 0 0 1 1 1 0 Involucrin of squamous epithelia N-terminus NUDIX PF00293.28 CRK21947.1 - 9e-07 29.0 0.1 4.1e-06 26.9 0.1 1.9 1 1 0 1 1 1 1 NUDIX domain NUDIX PF00293.28 CRK21948.1 - 8.6e-16 58.2 0.1 1.8e-15 57.1 0.0 1.5 2 0 0 2 2 2 1 NUDIX domain NUDIX PF00293.28 CRK21949.1 - 5.5e-06 26.5 0.0 9.3e-06 25.7 0.0 1.5 1 1 0 1 1 1 1 NUDIX domain NUDIX PF00293.28 CRK21950.1 - 3.4e-15 56.3 0.1 7.1e-15 55.2 0.0 1.5 2 0 0 2 2 2 1 NUDIX domain SIR2 PF02146.17 CRK21951.1 - 2.2e-51 174.3 0.0 3.1e-51 173.8 0.0 1.2 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 CRK21951.1 - 0.11 12.2 0.1 2 8.2 0.0 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Peptidase_S8 PF00082.22 CRK21952.1 - 1.8e-37 129.2 8.1 3.6e-37 128.2 8.1 1.4 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 CRK21952.1 - 1.6e-21 76.8 0.3 4.4e-21 75.3 0.3 1.8 1 0 0 1 1 1 1 Peptidase inhibitor I9 Beach PF02138.18 CRK21954.1 - 5.2e-119 396.7 0.0 8e-119 396.1 0.0 1.3 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 CRK21954.1 - 6.6e-10 39.0 0.0 1.7e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 CRK21954.1 - 4.7e-09 36.6 0.0 9.8e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.32 CRK21954.1 - 0.00071 20.3 5.1 0.23 12.4 0.1 4.4 4 0 0 4 4 4 1 WD domain, G-beta repeat DUF4704 PF15787.5 CRK21954.1 - 0.13 11.4 0.3 0.57 9.4 0.3 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4704) Rad21_Rec8_N PF04825.13 CRK21956.1 - 1.4e-29 102.5 0.0 3e-29 101.4 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 CRK21956.1 - 0.00016 20.9 0.0 0.00016 20.9 0.0 2.4 3 0 0 3 3 3 1 Conserved region of Rad21 / Rec8 like protein DUF2283 PF10049.9 CRK21956.1 - 0.03 14.6 0.4 0.087 13.1 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2283) GDI PF00996.18 CRK21957.1 - 5e-23 81.3 0.0 3e-22 78.8 0.0 1.8 1 1 0 1 1 1 1 GDP dissociation inhibitor Acetyltransf_17 PF17668.1 CRK21957.1 - 0.035 14.9 0.2 0.083 13.7 0.2 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ferric_reduct PF01794.19 CRK21959.1 - 3e-19 69.3 2.6 3e-19 69.3 2.6 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 CRK21959.1 - 5.6e-15 55.8 0.0 3.3e-14 53.3 0.0 2.1 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 CRK21959.1 - 1.2e-12 47.9 0.0 3.3e-12 46.5 0.0 1.8 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 CRK21959.1 - 0.00021 21.9 0.0 0.069 13.8 0.0 2.5 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain Complex1_LYR PF05347.15 CRK21960.1 - 1.9e-19 69.4 4.8 4.2e-19 68.4 4.8 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) WD40 PF00400.32 CRK21960.1 - 1.1e-08 35.5 6.5 0.03 15.2 0.0 5.6 4 1 1 5 5 5 3 WD domain, G-beta repeat Complex1_LYR_2 PF13233.6 CRK21960.1 - 2.2e-06 28.3 2.0 4.6e-06 27.3 2.0 1.5 1 0 0 1 1 1 1 Complex1_LYR-like DUF3176 PF11374.8 CRK21960.1 - 0.18 12.1 0.8 1.1 9.5 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3176) Complex1_LYR_1 PF13232.6 CRK21960.1 - 0.19 12.3 0.4 0.45 11.1 0.4 1.6 1 0 0 1 1 1 0 Complex1_LYR-like CDC45 PF02724.14 CRK21960.1 - 1.8 6.7 4.2 3.8 5.7 4.2 1.5 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 CRK21960.1 - 8.8 4.4 9.4 15 3.6 9.4 1.3 1 0 0 1 1 1 0 Nop14-like family DUF5401 PF17380.2 CRK21961.1 - 0.16 10.0 0.3 0.24 9.4 0.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Carb_anhydrase PF00194.21 CRK21962.1 - 3.7e-11 43.1 0.0 4.4e-11 42.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase CFEM PF05730.11 CRK21969.1 - 9.5e-06 25.6 8.0 2.3e-05 24.4 8.0 1.6 1 0 0 1 1 1 1 CFEM domain CFEM PF05730.11 CRK21970.1 - 6.2e-06 26.2 12.1 8.3e-06 25.8 12.1 1.2 1 0 0 1 1 1 1 CFEM domain DUF832 PF05734.11 CRK21970.1 - 0.16 11.4 3.6 0.19 11.2 3.6 1.1 1 0 0 1 1 1 0 Herpesvirus protein of unknown function (DUF832) APH PF01636.23 CRK21972.1 - 2.6e-09 37.4 0.2 5.7e-09 36.2 0.2 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Rota_Capsid_VP6 PF00980.17 CRK21972.1 - 0.15 10.9 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Rotavirus major capsid protein VP6 DUF3435 PF11917.8 CRK21973.1 - 5e-18 65.2 1.2 1.3e-17 63.8 1.2 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3435) zf-H2C2_2 PF13465.6 CRK21973.1 - 0.00018 21.8 5.7 0.089 13.3 0.3 3.7 3 0 0 3 3 3 2 Zinc-finger double domain FUSC PF04632.12 CRK21973.1 - 0.12 10.9 0.9 0.17 10.4 0.9 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family zf-C2H2_4 PF13894.6 CRK21973.1 - 0.34 11.9 13.5 0.8 10.7 0.1 4.6 4 0 0 4 4 4 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CRK21974.1 - 0.001 19.4 10.5 0.047 14.1 0.3 3.8 4 0 0 4 4 4 2 Zinc-finger double domain zf-BED PF02892.15 CRK21974.1 - 0.0033 17.4 0.3 0.0088 16.0 0.3 1.7 1 0 0 1 1 1 1 BED zinc finger zf-C2H2_4 PF13894.6 CRK21974.1 - 0.057 14.3 14.2 0.28 12.1 0.1 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger SRF-TF PF00319.18 CRK21975.1 - 3e-05 23.4 0.5 4.4e-05 22.9 0.5 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) F-box-like PF12937.7 CRK21978.1 - 2.9e-06 27.1 0.8 0.00012 21.9 0.1 2.5 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 CRK21978.1 - 6.7e-06 26.0 0.2 1.7e-05 24.7 0.1 1.8 2 0 0 2 2 2 1 F-box F-box PF00646.33 CRK21978.1 - 1.2e-05 25.0 0.7 0.00022 21.0 0.1 2.6 2 0 0 2 2 2 1 F-box domain Ferric_reduct PF01794.19 CRK21979.1 - 2e-06 28.0 12.3 2e-06 28.0 12.3 3.2 2 1 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 CRK21979.1 - 0.0074 16.4 0.1 0.048 13.8 0.1 2.2 2 1 0 2 2 2 1 Ferric reductase NAD binding domain DUF805 PF05656.14 CRK21979.1 - 8.9 6.8 14.5 0.61 10.5 2.6 2.8 1 1 0 2 2 2 0 Protein of unknown function (DUF805) SRF-TF PF00319.18 CRK21980.1 - 9e-06 25.1 0.0 1.9e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) BRCT_2 PF16589.5 CRK21981.1 - 2.8e-09 37.3 0.0 0.00039 20.8 0.0 2.4 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 CRK21981.1 - 1.2e-07 32.0 0.0 0.00037 20.8 0.0 2.5 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain BUD22 PF09073.10 CRK21981.1 - 0.0001 21.8 26.3 0.0032 16.9 12.1 2.2 2 0 0 2 2 2 2 BUD22 DUF4471 PF14740.6 CRK21981.1 - 0.011 15.0 0.0 0.011 15.0 0.0 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4471) DUF2048 PF09752.9 CRK21981.1 - 0.036 13.2 0.1 0.063 12.4 0.1 1.3 1 0 0 1 1 1 0 Abhydrolase domain containing 18 PTCB-BRCT PF12738.7 CRK21981.1 - 0.045 13.7 0.0 0.099 12.6 0.0 1.6 1 0 0 1 1 1 0 twin BRCT domain Pox_H7 PF04787.12 CRK21981.1 - 0.066 13.7 0.0 0.21 12.1 0.0 1.7 2 0 0 2 2 2 0 Late protein H7 YqfQ PF14181.6 CRK21981.1 - 0.081 13.1 13.1 1.1 9.5 2.2 3.1 3 0 0 3 3 3 0 YqfQ-like protein CtaG_Cox11 PF04442.14 CRK21981.1 - 0.083 12.9 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein CtaG/Cox11 Tim54 PF11711.8 CRK21981.1 - 0.14 10.9 13.6 0.27 10.0 0.7 2.8 3 0 0 3 3 3 0 Inner membrane protein import complex subunit Tim54 SpoIIP PF07454.11 CRK21981.1 - 0.48 9.8 13.1 0.36 10.2 0.6 2.7 3 0 0 3 3 3 0 Stage II sporulation protein P (SpoIIP) HET PF06985.11 CRK21981.1 - 0.49 10.7 4.7 10 6.5 0.3 2.5 2 0 0 2 2 2 0 Heterokaryon incompatibility protein (HET) DUF719 PF05334.13 CRK21981.1 - 0.84 9.8 12.6 1.6 8.9 1.4 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF719) Serinc PF03348.15 CRK21981.1 - 2.1 7.2 8.9 2.7 6.8 2.1 2.1 2 0 0 2 2 2 0 Serine incorporator (Serinc) RPA43_OB PF17875.1 CRK21981.1 - 2.4 8.8 15.4 5 7.8 1.0 3.2 3 0 0 3 3 3 0 RPA43 OB domain in RNA Pol I RXT2_N PF08595.11 CRK21981.1 - 2.6 8.0 25.6 2.3 8.3 5.7 3.3 3 0 0 3 3 3 0 RXT2-like, N-terminal U1snRNP70_N PF12220.8 CRK21981.1 - 3.5 8.3 16.4 2.6 8.7 3.1 3.4 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal MRNIP PF15749.5 CRK21981.1 - 3.8 8.3 17.3 3.3 8.5 1.1 3.2 3 0 0 3 3 3 0 MRN-interacting protein EFTUD2 PF16004.5 CRK21981.1 - 4.8 7.8 31.7 2.3 8.8 7.2 3.2 3 0 0 3 3 3 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus DUF4349 PF14257.6 CRK21982.1 - 0.47 9.9 0.9 0.53 9.7 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) DUF2207 PF09972.9 CRK21982.1 - 2.9 6.6 5.7 3.4 6.3 5.7 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) BRCT_2 PF16589.5 CRK21983.1 - 2e-07 31.3 0.0 0.016 15.6 0.0 2.3 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 CRK21983.1 - 3.6e-06 27.3 0.1 0.16 12.4 0.2 3.3 2 1 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain BRCT_3 PF18428.1 CRK21983.1 - 0.071 13.2 0.0 11 6.1 0.0 2.3 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain Ank_2 PF12796.7 CRK21985.1 - 1.1e-09 38.7 7.0 7.3e-05 23.3 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeats (3 copies) Ank PF00023.30 CRK21985.1 - 5.1e-07 29.8 5.0 0.03 14.8 0.0 5.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 CRK21985.1 - 1.1e-06 28.8 6.8 0.0025 18.1 0.1 5.0 6 0 0 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CRK21985.1 - 4.8e-06 26.5 8.6 0.052 14.1 0.0 6.8 7 0 0 7 7 7 1 Ankyrin repeat F-box PF00646.33 CRK21985.1 - 0.0019 18.1 0.3 0.0044 16.9 0.3 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 CRK21985.1 - 0.039 13.9 0.6 0.1 12.5 0.6 1.7 1 0 0 1 1 1 0 F-box-like F-box_4 PF15966.5 CRK21985.1 - 0.066 13.1 0.0 2.4 8.1 0.0 2.4 2 0 0 2 2 2 0 F-box DUF1192 PF06698.11 CRK21986.1 - 0.014 15.4 0.5 0.022 14.8 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) DUF3435 PF11917.8 CRK21990.1 - 5.4e-55 187.0 0.4 7.4e-55 186.6 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) SNAPc19 PF15497.6 CRK21992.1 - 0.02 15.3 0.1 0.023 15.1 0.1 1.1 1 0 0 1 1 1 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 PP_M1 PF03012.14 CRK21992.1 - 0.061 12.9 0.1 0.083 12.4 0.1 1.3 1 1 1 2 2 2 0 Phosphoprotein DUF2188 PF09954.9 CRK21992.1 - 0.16 12.2 0.1 0.2 11.8 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2188) Zn_clus PF00172.18 CRK21993.1 - 4.7e-09 36.2 12.0 8.8e-09 35.3 12.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cep57_CLD_2 PF14197.6 CRK21993.1 - 0.025 14.7 1.1 0.039 14.0 1.1 1.3 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Zn_clus PF00172.18 CRK21994.1 - 0.0007 19.7 8.5 0.0007 19.7 8.5 1.8 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Toxin_5 PF05294.13 CRK21994.1 - 0.15 12.5 5.4 0.45 11.0 5.4 1.8 1 0 0 1 1 1 0 Scorpion short toxin Draxin PF15550.6 CRK21995.1 - 0.25 11.2 31.7 0.34 10.7 31.7 1.1 1 0 0 1 1 1 0 Draxin GREB1 PF15782.5 CRK21995.1 - 0.31 8.1 11.6 0.38 7.8 11.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer C1_2 PF03107.16 CRK21995.1 - 1.3 9.4 5.0 2.6 8.4 5.0 1.5 1 0 0 1 1 1 0 C1 domain AF-4 PF05110.13 CRK21995.1 - 5.6 4.9 23.7 6.3 4.7 23.7 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein TF_Zn_Ribbon PF08271.12 CRK21995.1 - 6.3 6.4 8.8 2.7 7.6 0.1 3.3 2 1 1 3 3 3 0 TFIIB zinc-binding Borrelia_P83 PF05262.11 CRK21995.1 - 7.3 5.0 32.7 8.8 4.7 32.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein OTT_1508_deam PF14441.6 CRK21996.1 - 1.1e-15 57.4 2.9 1.1e-15 57.4 2.9 2.1 2 0 0 2 2 2 1 OTT_1508-like deaminase zf_C2H2_6 PF18450.1 CRK21996.1 - 0.043 13.5 0.6 0.099 12.4 0.6 1.6 1 0 0 1 1 1 0 Zinc Finger domain Pkinase PF00069.25 CRK21998.1 - 8.4e-22 77.8 0.0 1.1e-09 38.1 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CRK21998.1 - 1.4e-06 27.8 0.0 0.024 13.9 0.0 2.8 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 CRK21998.1 - 0.0006 19.2 0.1 1.3 8.3 0.0 2.9 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.14 CRK21998.1 - 0.019 14.3 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CRK21998.1 - 0.022 14.7 0.8 0.044 13.7 0.1 1.9 2 1 0 2 2 2 0 Phosphotransferase enzyme family Herpes_UL25 PF01499.16 CRK22002.1 - 0.00064 18.4 1.1 0.00075 18.1 1.1 1.1 1 0 0 1 1 1 1 Herpesvirus UL25 family YscO PF07321.12 CRK22002.1 - 0.01 15.8 6.8 0.01 15.8 6.8 1.6 2 0 0 2 2 2 0 Type III secretion protein YscO DUF2852 PF11014.8 CRK22002.1 - 0.029 14.5 1.2 0.05 13.8 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) SAT PF16073.5 CRK22002.1 - 0.059 13.1 0.0 0.079 12.7 0.0 1.3 1 0 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis bZIP_2 PF07716.15 CRK22002.1 - 0.098 12.8 1.0 0.098 12.8 1.0 3.4 2 1 2 4 4 4 0 Basic region leucine zipper ZapB PF06005.12 CRK22002.1 - 0.53 10.8 7.9 0.087 13.3 3.9 1.8 2 0 0 2 2 2 0 Cell division protein ZapB Metal_resist PF13801.6 CRK22002.1 - 3 8.1 13.5 0.12 12.6 6.5 1.9 2 0 0 2 2 2 0 Heavy-metal resistance RXT2_N PF08595.11 CRK22003.1 - 0.021 14.9 3.6 0.025 14.6 3.6 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal NPR1_like_C PF12313.8 CRK22003.1 - 0.077 12.5 0.3 0.11 12.0 0.3 1.2 1 0 0 1 1 1 0 NPR1/NIM1 like defence protein C terminal Mito_carr PF00153.27 CRK22015.1 - 2.2e-25 88.4 0.0 2.3e-14 53.1 0.1 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein Serine_protease PF18405.1 CRK22015.1 - 0.0021 17.2 0.3 0.0037 16.5 0.2 1.3 1 1 0 1 1 1 1 Gammaproteobacterial serine protease MutS_I PF01624.20 CRK22034.1 - 2.7e-14 53.4 0.0 3.3e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 MutS domain I DnaJ PF00226.31 CRK22038.1 - 2.7e-17 62.6 2.8 2.7e-17 62.6 2.8 1.9 2 0 0 2 2 2 1 DnaJ domain TPR_1 PF00515.28 CRK22038.1 - 8.5e-13 47.5 1.5 1.6e-09 37.2 0.2 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CRK22038.1 - 2.6e-09 36.5 1.7 5.6e-06 26.1 0.2 2.8 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 CRK22038.1 - 5e-06 26.9 0.8 1.2e-05 25.8 0.3 1.9 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 CRK22038.1 - 5.4e-05 23.1 1.8 0.00013 21.9 0.1 2.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 CRK22038.1 - 0.00015 21.4 2.5 0.0087 15.7 0.4 2.9 2 1 1 3 3 3 1 TPR repeat TPR_16 PF13432.6 CRK22038.1 - 0.00044 20.8 0.0 0.34 11.6 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 CRK22038.1 - 0.00058 20.1 0.9 0.049 13.9 0.6 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat NARP1 PF12569.8 CRK22038.1 - 0.00092 18.2 1.1 0.00092 18.2 1.1 1.6 1 1 1 2 2 2 1 NMDA receptor-regulated protein 1 TPR_9 PF13371.6 CRK22038.1 - 0.0011 19.1 0.3 0.0029 17.7 0.3 1.8 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 CRK22038.1 - 0.0017 19.0 2.6 0.29 12.0 0.1 3.0 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 CRK22038.1 - 0.0044 17.3 2.0 0.079 13.4 0.0 3.1 3 1 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CRK22038.1 - 0.062 13.5 2.2 0.069 13.4 0.3 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 IFP_35_N PF07334.13 CRK22038.1 - 0.11 12.6 1.4 0.19 11.8 1.4 1.5 1 0 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus TPR_6 PF13174.6 CRK22038.1 - 0.15 12.8 1.7 1.6 9.6 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 CRK22038.1 - 0.17 11.8 0.7 6.1 6.9 0.2 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat Snurportin1 PF11538.8 CRK22038.1 - 0.74 10.1 4.1 1.8 8.8 0.7 2.7 3 0 0 3 3 3 0 Snurportin1 NDT80_PhoG PF05224.12 CRK22039.1 - 1.5e-30 106.8 0.0 3.1e-30 105.8 0.0 1.5 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Glucosamine_iso PF01182.20 CRK22040.1 - 1e-21 77.8 0.1 2.4e-21 76.6 0.0 1.6 2 1 0 2 2 2 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Hexokinase_2 PF03727.16 CRK22042.1 - 3.1e-53 180.7 0.0 5.3e-53 179.9 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 CRK22042.1 - 1.6e-42 145.7 0.0 2.9e-42 144.8 0.0 1.4 1 0 0 1 1 1 1 Hexokinase zf-Nse PF11789.8 CRK22043.1 - 7.3e-17 60.9 0.5 1.3e-16 60.1 0.5 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 CRK22043.1 - 1e-06 28.6 0.8 1.7e-06 27.9 0.8 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 CRK22043.1 - 0.012 15.9 1.0 0.02 15.2 1.0 1.3 1 0 0 1 1 1 0 Ring finger domain zf-rbx1 PF12678.7 CRK22043.1 - 0.016 15.5 0.8 0.028 14.7 0.8 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 CRK22043.1 - 0.026 14.1 0.0 0.046 13.4 0.0 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF5566 PF17721.1 CRK22043.1 - 0.049 13.9 0.7 0.19 12.0 0.0 2.1 2 1 1 3 3 3 0 Family of unknown function (DUF5566) ApoLp-III PF07464.11 CRK22043.1 - 0.055 13.6 0.3 0.11 12.6 0.1 1.5 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) zf-C3HC4_2 PF13923.6 CRK22043.1 - 0.096 12.5 0.2 0.17 11.7 0.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CRK22043.1 - 0.13 12.3 0.2 0.24 11.5 0.2 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-MIZ PF02891.20 CRK22043.1 - 0.16 11.7 0.4 0.3 10.9 0.4 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger PAS_9 PF13426.7 CRK22044.1 - 6.5e-14 52.1 0.0 1.1e-13 51.3 0.0 1.3 1 0 0 1 1 1 1 PAS domain Cupin_2 PF07883.11 CRK22044.1 - 1.7e-13 50.0 0.2 3.2e-13 49.2 0.2 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 CRK22044.1 - 3.6e-06 26.7 0.0 6.4e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 CRK22044.1 - 0.00011 22.1 0.0 0.0002 21.3 0.0 1.4 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.12 CRK22044.1 - 0.0067 16.1 0.0 0.024 14.3 0.0 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF861) MannoseP_isomer PF01050.18 CRK22044.1 - 0.0095 15.8 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase PAS PF00989.25 CRK22044.1 - 0.012 15.5 0.0 0.29 11.1 0.0 2.2 1 1 0 1 1 1 0 PAS fold PAS_3 PF08447.12 CRK22044.1 - 0.032 14.5 0.1 6.8 7.0 0.0 2.3 2 0 0 2 2 2 0 PAS fold Cupin_6 PF12852.7 CRK22044.1 - 0.047 13.4 0.2 0.17 11.6 0.0 1.9 2 0 0 2 2 2 0 Cupin DMSP_lyase PF16867.5 CRK22044.1 - 0.16 11.6 0.1 1.8 8.2 0.0 2.2 2 0 0 2 2 2 0 Dimethlysulfonioproprionate lyase Fapy_DNA_glyco PF01149.24 CRK22045.1 - 1.3e-37 128.9 0.1 2.9e-37 127.8 0.1 1.6 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 CRK22045.1 - 1e-21 76.7 0.0 2e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.11 CRK22045.1 - 9.8e-05 21.3 0.0 0.0009 18.1 0.0 2.0 2 0 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) Ribosomal_S13 PF00416.22 CRK22045.1 - 0.0057 17.1 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S13/S18 Peptidase_S10 PF00450.22 CRK22046.1 - 2.5e-51 175.4 0.0 3.3e-51 175.0 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase Bac_rhamnosid_C PF17390.2 CRK22046.1 - 0.096 12.5 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase C-terminal domain L71 PF02448.15 CRK22046.1 - 0.22 12.0 0.5 0.4 11.1 0.5 1.4 1 0 0 1 1 1 0 L71 family Sugar_tr PF00083.24 CRK22047.1 - 1.1e-93 314.6 24.3 1.3e-93 314.4 24.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK22047.1 - 2.1e-33 115.7 22.8 2.1e-33 115.7 22.8 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily FMN_dh PF01070.18 CRK22050.1 - 7.8e-92 308.0 0.4 1.9e-90 303.4 0.4 2.4 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 CRK22050.1 - 8.9e-16 57.8 0.0 1.8e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 CRK22050.1 - 5.2e-06 25.8 0.1 8.8e-06 25.1 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 CRK22050.1 - 5.7e-05 22.3 0.4 0.00014 21.0 0.1 1.6 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 CRK22050.1 - 0.017 14.5 0.2 0.03 13.7 0.2 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase ThiG PF05690.14 CRK22050.1 - 0.02 14.2 0.0 0.71 9.1 0.1 2.4 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 CRK22050.1 - 0.11 11.9 0.1 0.24 10.9 0.1 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein Mannosidase_ig PF17786.1 CRK22051.1 - 7.4e-18 65.0 0.1 1.7e-17 63.8 0.1 1.7 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 CRK22051.1 - 3.1e-05 24.6 0.0 0.00011 22.9 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Ig_mannosidase PF17753.1 CRK22051.1 - 6.8e-05 22.5 0.0 0.00028 20.6 0.0 2.0 2 0 0 2 2 2 1 Ig-fold domain Glyco_hydro_2_C PF02836.17 CRK22051.1 - 0.00082 18.6 0.0 0.0017 17.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Arylsulfotran_2 PF14269.6 CRK22052.1 - 1.5e-56 192.0 0.3 2e-56 191.6 0.3 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 CRK22052.1 - 7.7e-12 44.8 0.0 1.5e-10 40.6 0.0 2.3 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) MFS_1 PF07690.16 CRK22053.1 - 2.6e-28 99.0 40.8 7.6e-19 67.8 20.1 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Frag1 PF10277.9 CRK22053.1 - 0.0019 17.8 0.4 0.0036 16.9 0.4 1.5 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Helo_like_N PF17111.5 CRK22054.1 - 0.0049 16.3 0.6 0.0075 15.7 0.6 1.3 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Desmo_N PF06771.11 CRK22054.1 - 0.021 15.2 0.4 0.044 14.1 0.4 1.6 1 0 0 1 1 1 0 Viral Desmoplakin N-terminus Clr5 PF14420.6 CRK22056.1 - 1e-16 60.9 2.9 2e-16 59.9 2.3 1.8 2 0 0 2 2 2 1 Clr5 domain DUF3987 PF13148.6 CRK22056.1 - 0.14 11.1 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Arrestin_C PF02752.22 CRK22057.1 - 7.8e-16 58.8 0.0 1.6e-15 57.8 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CRK22057.1 - 4.6e-06 26.7 0.0 9.9e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Apolipoprotein PF01442.18 CRK22057.1 - 0.0063 16.4 0.8 0.018 14.9 0.8 1.7 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain LDB19 PF13002.7 CRK22057.1 - 0.02 14.6 0.0 0.095 12.4 0.0 2.0 2 0 0 2 2 2 0 Arrestin_N terminal like eRF1_3 PF03465.15 CRK22057.1 - 0.072 13.6 0.1 1.2 9.7 0.0 2.4 2 0 0 2 2 2 0 eRF1 domain 3 Prefoldin_2 PF01920.20 CRK22058.1 - 0.061 13.3 0.5 0.1 12.6 0.5 1.3 1 0 0 1 1 1 0 Prefoldin subunit Glyco_hydro_32N PF00251.20 CRK22060.1 - 1.1e-47 163.1 0.0 1.5e-47 162.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 CRK22060.1 - 1.5e-24 86.8 0.0 2.2e-24 86.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal BNR_2 PF13088.6 CRK22060.1 - 0.086 12.1 1.2 0.46 9.7 1.2 2.0 1 1 0 1 1 1 0 BNR repeat-like domain DUF4975 PF16346.5 CRK22060.1 - 0.14 12.2 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4975) BNR PF02012.20 CRK22060.1 - 0.2 11.7 0.2 0.2 11.7 0.2 3.6 3 0 0 3 3 3 0 BNR/Asp-box repeat Sugar_tr PF00083.24 CRK22061.1 - 6e-79 266.0 18.2 7.1e-79 265.8 18.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK22061.1 - 7.2e-20 71.2 27.7 7.2e-20 71.2 27.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 CRK22061.1 - 3.3e-05 22.6 19.0 0.00023 19.9 1.9 2.6 2 1 1 3 3 3 2 MFS/sugar transport protein WD40 PF00400.32 CRK22062.1 - 1.7e-13 50.8 12.6 0.00062 20.5 0.5 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK22062.1 - 5.3e-09 36.2 0.0 0.0049 17.1 0.0 3.4 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CRK22062.1 - 0.001 19.0 0.0 0.0068 16.3 0.0 2.0 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 CRK22062.1 - 0.0057 15.2 0.0 0.01 14.4 0.0 1.4 1 0 0 1 1 1 1 Cytochrome D1 heme domain PD40 PF07676.12 CRK22062.1 - 0.015 15.2 0.0 3.7 7.6 0.0 2.8 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat VID27 PF08553.10 CRK22062.1 - 0.09 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain EF_assoc_2 PF08356.12 CRK22063.1 - 6.8e-36 122.1 0.0 1.3e-35 121.2 0.0 1.5 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.12 CRK22063.1 - 6.9e-30 102.5 1.5 1.4e-29 101.5 1.5 1.5 1 0 0 1 1 1 1 EF hand associated Ras PF00071.22 CRK22063.1 - 7.3e-20 71.2 0.0 1.5e-13 50.7 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 CRK22063.1 - 8e-13 48.7 0.0 9.9e-09 35.5 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 CRK22063.1 - 8.9e-08 32.2 0.0 0.0019 18.2 0.0 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_1 PF00036.32 CRK22063.1 - 4.6e-07 28.9 5.3 0.0054 16.2 1.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CRK22063.1 - 9.1e-07 29.2 1.6 0.0015 18.9 0.2 2.5 2 0 0 2 2 2 2 EF-hand domain pair Dynamin_N PF00350.23 CRK22063.1 - 1.6e-06 28.3 0.1 0.063 13.3 0.0 3.4 3 1 1 4 4 4 2 Dynamin family EF-hand_6 PF13405.6 CRK22063.1 - 5.3e-06 25.9 5.5 0.0054 16.6 0.4 2.6 2 0 0 2 2 2 2 EF-hand domain AAA_16 PF13191.6 CRK22063.1 - 0.00011 22.6 0.0 0.18 12.2 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain EF-hand_5 PF13202.6 CRK22063.1 - 0.00039 19.8 8.3 0.023 14.2 3.2 2.7 2 0 0 2 2 2 2 EF hand AAA_29 PF13555.6 CRK22063.1 - 0.00046 19.9 0.0 0.47 10.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_28 PF13521.6 CRK22063.1 - 0.0012 19.2 0.0 1.6 8.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 CRK22063.1 - 0.0062 16.8 0.0 0.44 10.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 CRK22063.1 - 0.011 15.5 0.0 0.14 11.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 CRK22063.1 - 0.012 15.5 0.0 1.3 9.0 0.0 3.1 2 1 0 3 3 3 0 RsgA GTPase GTP_EFTU PF00009.27 CRK22063.1 - 0.013 15.1 0.0 6.2 6.3 0.0 3.2 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain Ploopntkinase3 PF18751.1 CRK22063.1 - 0.024 14.5 0.0 3.8 7.4 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 RNA_helicase PF00910.22 CRK22063.1 - 0.026 14.9 0.0 0.46 10.9 0.0 2.4 2 0 0 2 2 2 0 RNA helicase ABC_tran PF00005.27 CRK22063.1 - 0.031 14.8 0.0 2.6 8.6 0.0 2.5 2 0 0 2 2 2 0 ABC transporter Septin PF00735.18 CRK22063.1 - 0.14 11.4 0.0 0.32 10.2 0.0 1.5 2 0 0 2 2 2 0 Septin DUF815 PF05673.13 CRK22063.1 - 0.15 11.2 0.0 1.2 8.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) EF-hand_10 PF14788.6 CRK22063.1 - 0.16 11.8 2.8 0.41 10.5 0.2 2.3 2 0 0 2 2 2 0 EF hand EF-hand_8 PF13833.6 CRK22063.1 - 6.1 6.8 6.5 4.7 7.1 1.3 2.4 2 0 0 2 2 2 0 EF-hand domain pair Atx10homo_assoc PF09759.9 CRK22064.1 - 7.3e-11 42.0 0.0 1.7e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain Peptidase_S8_N PF16361.5 CRK22064.1 - 0.016 15.7 0.2 7.5 7.0 0.0 2.4 2 0 0 2 2 2 0 N-terminal of Subtilase family Spc42p PF11544.8 CRK22064.1 - 0.022 14.7 1.1 8.7 6.4 0.1 2.5 2 0 0 2 2 2 0 Spindle pole body component Spc42p Ribosomal_L29 PF00831.23 CRK22064.1 - 0.094 12.7 0.3 16 5.6 0.0 2.7 2 0 0 2 2 2 0 Ribosomal L29 protein MAP70 PF07058.11 CRK22064.1 - 1.8 7.2 3.0 18 3.9 0.2 2.1 2 0 0 2 2 2 0 Microtubule-associated protein 70 Hydrolase_like PF13242.6 CRK22067.1 - 5.6e-13 48.8 0.1 7.8e-13 48.3 0.1 1.2 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 CRK22067.1 - 7.3e-05 23.1 0.0 8.8e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CRK22067.1 - 0.006 16.7 0.0 0.0081 16.3 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase UPF0149 PF03695.13 CRK22068.1 - 0.095 13.0 0.4 0.11 12.8 0.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0149) Peptidase_S9 PF00326.21 CRK22070.1 - 4.9e-26 91.5 0.4 5.1e-26 91.5 0.4 1.0 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 CRK22084.1 - 2.3e-05 24.3 0.8 0.0026 17.6 0.3 2.0 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CRK22084.1 - 0.00013 22.7 0.9 0.00014 22.5 0.9 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 CRK22084.1 - 0.006 16.7 0.0 0.0068 16.6 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain DUF915 PF06028.11 CRK22084.1 - 0.039 13.3 0.0 0.05 12.9 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) DUF3089 PF11288.8 CRK22084.1 - 0.058 12.9 0.0 0.075 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Hydrolase_4 PF12146.8 CRK22084.1 - 0.083 12.1 0.0 0.093 12.0 0.0 1.1 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Thr_synth_N PF14821.6 CRK22103.1 - 1.1e-23 83.2 0.0 1.8e-23 82.5 0.0 1.3 1 0 0 1 1 1 1 Threonine synthase N terminus CAP59_mtransfer PF11735.8 CRK22104.1 - 2.1e-20 73.5 0.0 2.6e-20 73.2 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 PCI PF01399.27 CRK22105.1 - 0.013 16.0 0.1 0.016 15.7 0.1 1.2 1 0 0 1 1 1 0 PCI domain Tubulin_C PF03953.17 CRK22107.1 - 3e-58 195.4 0.2 1.6e-39 134.9 0.1 2.5 2 0 0 2 2 2 2 Tubulin C-terminal domain Tubulin PF00091.25 CRK22107.1 - 9e-50 169.6 0.0 1.6e-49 168.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.6 CRK22107.1 - 0.0059 16.3 0.0 0.023 14.4 0.0 2.0 1 0 0 1 1 1 1 Tubulin domain PRKG1_interact PF15898.5 CRK22107.1 - 0.015 16.2 7.5 0.028 15.3 6.9 1.7 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain VWA_CoxE PF05762.14 CRK22107.1 - 0.027 13.8 0.0 2.9 7.2 0.0 2.4 2 0 0 2 2 2 0 VWA domain containing CoxE-like protein SKA1 PF07160.12 CRK22107.1 - 0.097 12.5 2.7 0.2 11.5 2.7 1.4 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 DUF4407 PF14362.6 CRK22107.1 - 0.14 11.5 8.2 0.3 10.4 8.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PspA_IM30 PF04012.12 CRK22107.1 - 0.37 10.3 12.4 0.9 9.1 11.8 1.8 1 1 0 1 1 1 0 PspA/IM30 family Csm1_N PF18504.1 CRK22107.1 - 0.59 10.5 9.1 0.061 13.7 0.9 2.7 1 1 1 2 2 2 0 Csm1 N-terminal domain Atg14 PF10186.9 CRK22107.1 - 0.67 9.0 8.5 1.1 8.3 8.5 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DivIC PF04977.15 CRK22107.1 - 0.92 9.3 12.3 0.56 10.0 3.5 3.2 2 1 1 3 3 3 0 Septum formation initiator GAS PF13851.6 CRK22107.1 - 1.4 8.3 11.9 2.9 7.2 11.9 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 CRK22107.1 - 2.9 6.7 13.4 6.4 5.6 13.4 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 CRK22107.1 - 3 7.9 11.6 6 6.9 11.6 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.8 CRK22107.1 - 3.6 7.7 14.7 2.8 8.0 11.4 1.9 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Uso1_p115_C PF04871.13 CRK22107.1 - 8.2 6.8 13.0 52 4.2 13.0 2.3 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region EF-hand_4 PF12763.7 CRK22109.1 - 9.2e-29 99.5 0.0 2.2e-11 43.6 0.0 3.4 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand Mito_carr PF00153.27 CRK22109.1 - 2e-23 82.1 0.2 3.4e-14 52.5 0.0 2.6 2 0 0 2 2 2 2 Mitochondrial carrier protein EF-hand_7 PF13499.6 CRK22109.1 - 6.8e-09 36.1 0.0 0.0018 18.7 0.0 4.7 5 0 0 5 5 4 1 EF-hand domain pair EF-hand_1 PF00036.32 CRK22109.1 - 0.00014 21.2 0.0 11 5.9 0.0 5.0 5 0 0 5 5 5 0 EF hand UBA PF00627.31 CRK22109.1 - 0.0048 16.8 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain YkyA PF10368.9 CRK22109.1 - 0.0082 15.8 22.9 0.0085 15.8 11.4 2.4 1 1 1 2 2 2 1 Putative cell-wall binding lipoprotein Exonuc_VII_L PF02601.15 CRK22109.1 - 0.0098 15.5 9.5 0.019 14.5 9.4 1.5 1 1 0 1 1 1 1 Exonuclease VII, large subunit EF-hand_6 PF13405.6 CRK22109.1 - 0.012 15.5 5.9 1.8 8.7 0.0 4.6 5 0 0 5 5 3 0 EF-hand domain PRKG1_interact PF15898.5 CRK22109.1 - 0.037 14.9 28.3 0.049 14.5 6.3 3.3 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain Spc7 PF08317.11 CRK22109.1 - 0.15 10.9 32.4 0.35 9.7 5.4 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein FUSC PF04632.12 CRK22109.1 - 0.19 10.2 14.1 0.31 9.5 14.1 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family CALCOCO1 PF07888.11 CRK22109.1 - 0.22 10.4 26.3 0.36 9.7 26.3 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF1664 PF07889.12 CRK22109.1 - 0.42 10.7 13.3 0.23 11.5 7.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ATG16 PF08614.11 CRK22109.1 - 0.52 10.5 35.2 5 7.3 34.8 2.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) MscS_porin PF12795.7 CRK22109.1 - 0.53 9.8 42.4 2.5 7.6 42.3 1.8 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain DUF3584 PF12128.8 CRK22109.1 - 0.6 7.6 30.8 0.84 7.1 30.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Leu_zip PF15294.6 CRK22109.1 - 0.74 9.3 18.8 1.3 8.5 18.2 1.6 1 1 0 1 1 1 0 Leucine zipper DUF4803 PF16061.5 CRK22109.1 - 0.87 9.0 3.7 1.4 8.3 3.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4803) TPR_MLP1_2 PF07926.12 CRK22109.1 - 1.1 9.3 37.0 1.7 8.7 18.3 2.7 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein LPP PF04728.13 CRK22109.1 - 1.3 9.5 19.5 0.87 10.0 3.1 3.7 2 1 1 3 3 3 0 Lipoprotein leucine-zipper Macoilin PF09726.9 CRK22109.1 - 1.3 7.5 14.6 2.2 6.7 14.6 1.3 1 0 0 1 1 1 0 Macoilin family Fib_alpha PF08702.10 CRK22109.1 - 1.5 9.0 18.4 0.1 12.8 9.1 2.2 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family YPEB PF14620.6 CRK22109.1 - 1.6 8.0 21.8 3.3 6.9 2.6 2.2 1 1 1 2 2 2 0 YpeB sporulation APG6_N PF17675.1 CRK22109.1 - 2.5 8.6 35.6 1.3 9.6 15.9 2.8 1 1 2 3 3 3 0 Apg6 coiled-coil region Filament PF00038.21 CRK22109.1 - 3.3 7.2 26.8 0.81 9.2 20.8 2.3 1 1 0 2 2 2 0 Intermediate filament protein DUF4407 PF14362.6 CRK22109.1 - 3.5 6.9 30.9 0.59 9.4 18.5 2.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) CENP-F_leu_zip PF10473.9 CRK22109.1 - 4.6 7.3 29.5 5.2 7.1 10.2 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Uso1_p115_C PF04871.13 CRK22109.1 - 5 7.5 34.5 11 6.4 16.4 2.8 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Fez1 PF06818.15 CRK22109.1 - 5 7.5 28.5 1.4 9.4 19.4 2.2 1 1 1 2 2 2 0 Fez1 DUF724 PF05266.14 CRK22109.1 - 6.3 6.6 23.8 37 4.1 11.3 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF724) IFT57 PF10498.9 CRK22109.1 - 6.5 5.6 21.5 3.3 6.6 9.6 2.2 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 DUF2730 PF10805.8 CRK22109.1 - 7.1 6.8 10.7 9.3 6.4 1.5 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) DUF3450 PF11932.8 CRK22109.1 - 8.2 5.6 30.7 3.2 7.0 18.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF4047 PF13256.6 CRK22109.1 - 8.7 6.6 6.5 5.1 7.3 3.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4047) TMF_TATA_bd PF12325.8 CRK22109.1 - 8.9 6.6 27.1 1.7 8.9 2.6 3.2 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding Seryl_tRNA_N PF02403.22 CRK22109.1 - 9 6.6 26.7 0.83 9.9 9.9 2.8 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain ADIP PF11559.8 CRK22109.1 - 9.3 6.3 34.9 0.53 10.4 9.8 3.1 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Csm1_N PF18504.1 CRK22109.1 - 9.3 6.7 27.8 0.1 13.0 0.9 4.2 3 1 1 4 4 4 0 Csm1 N-terminal domain Golgin_A5 PF09787.9 CRK22109.1 - 10 5.5 30.3 49 3.2 30.4 1.7 1 1 0 1 1 1 0 Golgin subfamily A member 5 DUF2730 PF10805.8 CRK22110.1 - 0.024 14.7 0.5 0.024 14.7 0.5 7.0 6 3 1 7 7 7 0 Protein of unknown function (DUF2730) tRNA-synt_2b PF00587.25 CRK22111.1 - 7e-19 68.5 0.0 1.9e-18 67.1 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Actin PF00022.19 CRK22111.1 - 3.1e-18 65.6 0.0 5.3e-17 61.5 0.0 2.4 1 1 0 1 1 1 1 Actin Seryl_tRNA_N PF02403.22 CRK22111.1 - 2.3e-05 24.6 0.3 5.6e-05 23.3 0.3 1.7 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain SPX PF03105.19 CRK22111.1 - 0.24 11.3 2.9 0.46 10.3 2.9 1.6 1 1 0 1 1 1 0 SPX domain GEN1_C PF18380.1 CRK22112.1 - 9.6e-30 103.6 0.7 3.6e-29 101.8 0.0 2.4 2 0 0 2 2 2 1 Holliday junction resolvase Gen1 C-terminal domain XPG_I PF00867.18 CRK22112.1 - 7.6e-26 90.3 0.0 1.5e-25 89.3 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 CRK22112.1 - 3.4e-07 30.7 0.0 7.3e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 CRK22112.1 - 0.086 12.3 0.1 0.24 10.8 0.0 1.7 2 0 0 2 2 2 0 XPG domain containing SWIB PF02201.18 CRK22115.1 - 1.8e-16 59.8 0.0 3.6e-16 58.8 0.0 1.5 2 0 0 2 2 2 1 SWIB/MDM2 domain Mo25 PF08569.11 CRK22116.1 - 1.2e-117 393.0 0.2 1.4e-117 392.7 0.2 1.0 1 0 0 1 1 1 1 Mo25-like SLATT_4 PF18186.1 CRK22116.1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 4 Sfi1 PF08457.10 CRK22117.1 - 5.2e-23 81.4 61.6 4.3e-13 48.7 49.9 3.0 1 1 1 2 2 2 2 Sfi1 spindle body protein Rav1p_C PF12234.8 CRK22118.1 - 6.9e-278 923.4 0.0 8.6e-278 923.0 0.0 1.1 1 0 0 1 1 1 1 RAVE protein 1 C terminal OPT PF03169.15 CRK22118.1 - 1.4e-114 384.0 15.5 1.9e-114 383.5 15.5 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein MadL PF03817.13 CRK22118.1 - 0.82 9.7 6.5 2.9 7.9 6.5 1.9 1 0 0 1 1 1 0 Malonate transporter MadL subunit Uso1_p115_head PF04869.14 CRK22120.1 - 2.2e-111 371.9 0.0 4.4e-111 371.0 0.0 1.5 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 CRK22120.1 - 1.7e-15 57.5 27.5 1.7e-15 57.5 27.5 4.1 1 1 2 3 3 3 1 Uso1 / p115 like vesicle tethering protein, C terminal region DUF1640 PF07798.11 CRK22120.1 - 0.98 9.4 34.0 1.3 9.0 5.1 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) DUF4525 PF15027.6 CRK22120.1 - 1.3 8.7 9.0 1.5 8.5 1.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4525) Golgin_A5 PF09787.9 CRK22120.1 - 2.5 7.5 46.5 0.075 12.5 19.3 2.7 1 1 2 3 3 3 0 Golgin subfamily A member 5 Baculo_PEP_C PF04513.12 CRK22120.1 - 3.5 7.7 15.2 1.2 9.1 5.1 3.4 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus XRN_M PF17846.1 CRK22121.1 - 2.2e-133 445.5 0.0 1.3e-132 443.0 0.0 2.0 1 1 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 CRK22121.1 - 9.8e-98 326.4 0.0 1.7e-97 325.6 0.0 1.4 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus RasGAP PF00616.19 CRK22121.1 - 5.6e-14 52.4 0.6 5.6e-11 42.5 0.6 2.5 1 1 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 CRK22121.1 - 1.3e-10 41.5 0.2 3.6e-10 40.1 0.2 1.7 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain zf-CCHC_2 PF13696.6 CRK22121.1 - 0.5 10.2 3.3 1.2 9.0 3.3 1.6 1 0 0 1 1 1 0 Zinc knuckle Alkyl_sulf_dimr PF14863.6 CRK22123.1 - 2.6e-60 202.9 0.0 4.1e-60 202.2 0.0 1.3 1 0 0 1 1 1 1 Alkyl sulfatase dimerisation Lactamase_B PF00753.27 CRK22123.1 - 2.5e-39 135.3 0.7 5.8e-39 134.2 0.7 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Alkyl_sulf_C PF14864.6 CRK22123.1 - 8.3e-32 110.1 0.0 1.4e-31 109.4 0.0 1.4 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Lactamase_B_2 PF12706.7 CRK22123.1 - 1.8e-06 27.6 0.0 4.1e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain TPR_16 PF13432.6 CRK22123.1 - 0.0071 17.0 0.1 0.0071 17.0 0.1 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 CRK22123.1 - 0.014 15.9 0.0 0.039 14.5 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat SCP2_2 PF13530.6 CRK22123.1 - 0.067 13.6 0.1 0.24 11.8 0.0 2.0 2 0 0 2 2 2 0 Sterol carrier protein domain TPR_11 PF13414.6 CRK22123.1 - 0.12 12.0 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 TPR repeat TPR_17 PF13431.6 CRK22123.1 - 0.17 12.3 0.0 3.3 8.3 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Sugar_tr PF00083.24 CRK22126.1 - 4e-33 115.0 8.7 4.5e-33 114.8 8.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK22126.1 - 2.3e-09 36.6 8.8 2.5e-09 36.5 8.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily RasGEF PF00617.19 CRK22127.1 - 2.2e-36 125.7 0.0 2.7e-36 125.4 0.0 1.0 1 0 0 1 1 1 1 RasGEF domain CtsR PF05848.11 CRK22127.1 - 0.029 14.3 0.0 0.048 13.6 0.0 1.3 1 0 0 1 1 1 0 CtsR N-terminal HTH domain DUF4653 PF15546.6 CRK22127.1 - 0.2 11.3 0.0 0.26 10.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) F-box-like PF12937.7 CRK22137.1 - 0.002 18.0 0.0 0.0027 17.6 0.0 1.3 1 0 0 1 1 1 1 F-box-like Med8 PF10232.9 CRK22148.1 - 3.6e-13 49.7 0.1 3.9e-13 49.5 0.1 1.0 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 Trimer_CC PF08954.11 CRK22148.1 - 0.05 13.2 0.7 0.092 12.3 0.1 1.9 2 0 0 2 2 2 0 Trimerisation motif AAA PF00004.29 CRK22149.1 - 2.7e-11 44.0 0.0 4.3e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CRK22149.1 - 7.8e-08 32.0 0.6 2.4e-07 30.5 0.0 2.0 2 0 0 2 2 2 1 AAA+ lid domain MCM_lid PF17855.1 CRK22149.1 - 8.8e-06 26.1 0.1 2.2e-05 24.8 0.1 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_bind PF09739.9 CRK22149.1 - 0.074 11.5 0.1 0.11 11.0 0.1 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor MoaE PF02391.17 CRK22151.1 - 0.11 12.7 0.0 0.12 12.7 0.0 1.2 1 0 0 1 1 1 0 MoaE protein p450 PF00067.22 CRK22153.1 - 1.3e-07 30.8 0.0 1.5e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ELYS PF13934.6 CRK22154.1 - 1.2e-66 224.9 1.7 1.6e-66 224.4 1.7 1.2 1 0 0 1 1 1 1 Nuclear pore complex assembly FAD_binding_6 PF00970.24 CRK22154.1 - 3e-25 88.5 0.0 6.8e-25 87.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.28 CRK22154.1 - 4.5e-24 84.4 0.3 9.6e-24 83.3 0.3 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FAD_binding_9 PF08021.11 CRK22154.1 - 0.0023 18.1 0.0 0.0045 17.2 0.0 1.5 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain dCMP_cyt_deam_1 PF00383.23 CRK22155.1 - 1.5e-06 28.0 0.0 1.9e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CRK22155.1 - 2.6e-06 27.2 0.0 3.3e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase OTT_1508_deam PF14441.6 CRK22155.1 - 0.049 13.7 0.2 0.076 13.0 0.2 1.3 1 0 0 1 1 1 0 OTT_1508-like deaminase zf-CCCH_6 PF18585.1 CRK22155.1 - 0.17 11.8 1.3 6.8 6.7 3.7 2.1 2 0 0 2 2 2 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 p450 PF00067.22 CRK22156.1 - 3.1e-69 233.9 0.0 3.9e-69 233.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Piwi PF02171.17 CRK22157.1 - 5.4e-79 265.6 0.0 7.1e-79 265.2 0.0 1.1 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 CRK22157.1 - 5.7e-17 62.6 0.0 6.2e-16 59.3 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain of argonaute ArgoL2 PF16488.5 CRK22157.1 - 1e-14 54.6 0.0 2.4e-13 50.2 0.0 2.5 2 0 0 2 2 2 1 Argonaute linker 2 domain ArgoL1 PF08699.10 CRK22157.1 - 2.5e-14 52.7 0.1 5.6e-14 51.5 0.1 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoMid PF16487.5 CRK22157.1 - 2.1e-06 27.9 0.0 1e-05 25.7 0.0 2.2 2 0 0 2 2 2 1 Mid domain of argonaute PAZ PF02170.22 CRK22157.1 - 3.2e-05 23.8 0.0 5.9e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 PAZ domain Acyl_transf_3 PF01757.22 CRK22158.1 - 1.5e-28 99.9 31.9 1e-27 97.1 31.9 2.2 1 1 0 1 1 1 1 Acyltransferase family DUF418 PF04235.12 CRK22158.1 - 0.00017 21.6 5.0 0.00017 21.6 5.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF418) DUF1624 PF07786.12 CRK22158.1 - 0.13 11.8 8.7 1.6 8.2 0.2 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF1624) Piwi PF02171.17 CRK22159.1 - 1.5e-80 270.6 0.0 1.9e-80 270.4 0.0 1.0 1 0 0 1 1 1 1 Piwi domain Acyl_transf_3 PF01757.22 CRK22160.1 - 2.3e-13 50.0 19.4 5.6e-13 48.7 19.4 1.6 1 1 0 1 1 1 1 Acyltransferase family DUF418 PF04235.12 CRK22160.1 - 0.00014 21.8 5.2 0.00014 21.8 5.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF418) zf-C2H2 PF00096.26 CRK22161.1 - 5.1e-10 39.3 25.8 2.8e-06 27.5 0.2 3.5 3 1 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CRK22161.1 - 1.4e-05 25.6 20.7 0.012 16.4 0.2 3.6 3 1 0 3 3 3 2 C2H2-type zinc finger FOXP-CC PF16159.5 CRK22161.1 - 7.2e-05 23.3 8.5 0.23 12.1 0.0 3.1 1 1 2 3 3 3 3 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 CRK22161.1 - 0.00023 21.4 1.7 0.0017 18.6 0.7 2.1 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 CRK22161.1 - 0.0014 18.8 2.2 6.2 7.2 2.3 3.3 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CRK22161.1 - 0.011 15.7 10.0 1 9.4 0.0 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger ET PF01684.16 CRK22161.1 - 0.033 14.5 0.7 0.052 13.9 0.7 1.4 1 0 0 1 1 1 0 ET module PTPS_related PF10131.9 CRK22161.1 - 0.27 9.5 0.0 0.29 9.4 0.0 1.0 1 0 0 1 1 1 0 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein zf-H2C2_2 PF13465.6 CRK22161.1 - 0.31 11.5 22.1 0.28 11.7 2.9 4.4 4 1 0 4 4 4 0 Zinc-finger double domain Lgl_C PF08596.10 CRK22162.1 - 4.3e-115 384.6 0.0 5.9e-115 384.1 0.0 1.2 1 0 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal ANAPC4_WD40 PF12894.7 CRK22162.1 - 3.1e-05 24.2 0.0 3.3 8.1 0.0 4.9 5 1 2 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CRK22162.1 - 6.3e-05 23.7 4.1 0.031 15.2 0.1 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat MgtE_N PF03448.17 CRK22163.1 - 0.045 14.4 0.1 0.057 14.0 0.1 1.2 1 0 0 1 1 1 0 MgtE intracellular N domain Fungal_trans PF04082.18 CRK22164.1 - 0.0099 14.9 0.5 0.019 14.0 0.5 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 CRK22165.1 - 3.1e-72 243.9 23.9 3.6e-72 243.7 23.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK22165.1 - 2.8e-16 59.4 50.8 1.3e-14 53.9 38.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ATP-synt_C PF00137.21 CRK22165.1 - 0.064 13.6 3.0 10 6.6 0.1 3.1 2 0 0 2 2 2 0 ATP synthase subunit C Fungal_trans PF04082.18 CRK22166.1 - 6.8e-17 61.4 0.0 1.2e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK22166.1 - 9.8e-09 35.2 8.1 9.8e-09 35.2 8.1 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 CRK22167.1 - 3e-47 161.2 33.5 3.5e-47 161.0 33.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK22167.1 - 4.4e-13 48.9 9.9 4.4e-13 48.9 9.9 2.1 1 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 CRK22167.1 - 3.1e-05 22.6 3.3 4.8e-05 22.0 3.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 CRK22167.1 - 0.00017 21.0 8.4 0.00017 21.0 8.4 1.8 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 CRK22167.1 - 9 4.4 7.9 5.8 5.1 4.9 2.2 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Helo_like_N PF17111.5 CRK22168.1 - 3.1e-46 157.4 0.1 4.4e-46 156.9 0.1 1.2 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins ADH_zinc_N_2 PF13602.6 CRK22169.1 - 1.3e-23 84.6 0.0 2.2e-23 83.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 CRK22169.1 - 1.2e-14 54.4 0.1 2e-14 53.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CRK22169.1 - 7.1e-08 32.3 0.7 9.9e-07 28.6 0.0 2.7 2 2 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain zf-C2H2 PF00096.26 CRK22170.1 - 5.5e-06 26.5 8.0 0.009 16.4 2.8 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type Fungal_trans PF04082.18 CRK22170.1 - 5.9e-06 25.5 0.3 9.5e-06 24.8 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.6 CRK22170.1 - 0.0039 17.9 12.8 0.017 15.9 1.2 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CRK22170.1 - 0.006 17.0 3.7 0.0081 16.5 0.5 2.7 2 0 0 2 2 2 1 Zinc-finger double domain CLP1_P PF16575.5 CRK22171.1 - 3.3e-36 124.9 0.0 4.6e-36 124.4 0.0 1.2 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_33 PF13671.6 CRK22171.1 - 0.12 12.6 0.0 0.3 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CRK22171.1 - 0.14 12.7 0.0 0.25 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_polI_A34 PF08208.11 CRK22172.1 - 9.7e-47 159.7 16.2 9.7e-47 159.7 16.2 5.3 2 2 3 5 5 5 1 DNA-directed RNA polymerase I subunit RPA34.5 PAP2_3 PF14378.6 CRK22173.1 - 5.1e-23 81.7 13.0 5.1e-23 81.7 13.0 1.9 2 0 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 CRK22173.1 - 1.4e-11 44.3 3.5 1.4e-11 44.3 3.5 2.9 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 CRK22174.1 - 7.4e-23 81.2 13.0 7.4e-23 81.2 13.0 1.9 2 0 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 CRK22174.1 - 1.3e-11 44.4 3.0 1.3e-11 44.4 3.0 2.9 2 1 0 2 2 2 1 PAP2 superfamily Pkinase PF00069.25 CRK22175.1 - 8.6e-23 81.0 0.0 6.4e-16 58.5 0.0 2.5 1 1 1 2 2 2 2 Protein kinase domain BST2 PF16716.5 CRK22175.1 - 0.00072 20.1 6.4 0.00072 20.1 6.4 2.9 2 1 2 4 4 3 1 Bone marrow stromal antigen 2 Pkinase_Tyr PF07714.17 CRK22175.1 - 0.0036 16.6 1.1 0.017 14.4 0.0 2.4 2 1 1 3 3 3 1 Protein tyrosine kinase DUF3584 PF12128.8 CRK22175.1 - 0.0052 14.4 10.7 0.0076 13.8 10.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Filament PF00038.21 CRK22175.1 - 0.01 15.4 8.4 0.011 15.3 7.0 1.7 1 1 0 1 1 1 0 Intermediate filament protein EzrA PF06160.12 CRK22175.1 - 0.021 13.0 6.6 0.041 12.1 6.6 1.4 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA UPF0242 PF06785.11 CRK22175.1 - 0.026 14.7 2.3 0.064 13.4 2.3 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus V-SNARE_C PF12352.8 CRK22175.1 - 0.099 12.9 1.9 4 7.8 0.1 3.1 3 0 0 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus Spc7 PF08317.11 CRK22175.1 - 0.15 10.9 13.2 0.4 9.5 13.2 1.7 1 0 0 1 1 1 0 Spc7 kinetochore protein PSI_PsaF PF02507.15 CRK22175.1 - 0.26 11.1 3.8 0.5 10.2 3.8 1.4 1 0 0 1 1 1 0 Photosystem I reaction centre subunit III Atg14 PF10186.9 CRK22175.1 - 0.52 9.3 8.2 1.2 8.1 8.2 1.6 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1690 PF07956.11 CRK22175.1 - 2.3 8.7 9.2 6.8 7.1 8.7 2.2 2 0 0 2 2 1 0 Protein of Unknown function (DUF1690) ADIP PF11559.8 CRK22175.1 - 6.3 6.9 17.2 32 4.6 6.4 3.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Macoilin PF09726.9 CRK22175.1 - 7.1 5.0 12.5 10 4.5 12.5 1.2 1 0 0 1 1 1 0 Macoilin family RRM_1 PF00076.22 CRK22177.1 - 3.9e-13 49.0 0.0 7e-13 48.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CRK22177.1 - 2.4e-06 27.2 0.0 5e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CRK22177.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif Lin-8 PF03353.15 CRK22177.1 - 2.6 7.5 5.9 4.5 6.8 5.9 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Ras PF00071.22 CRK22180.1 - 8.5e-34 116.5 0.0 9.6e-34 116.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CRK22180.1 - 9.5e-16 58.1 0.0 3.4e-15 56.3 0.0 1.7 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CRK22180.1 - 0.008 15.6 0.0 0.0098 15.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family HeH PF12949.7 CRK22181.1 - 2.5e-18 65.5 0.1 4.4e-18 64.7 0.1 1.5 1 0 0 1 1 1 1 HeH/LEM domain Thymopoietin PF08198.11 CRK22181.1 - 0.0038 16.8 0.1 0.0077 15.8 0.1 1.5 1 0 0 1 1 1 1 Thymopoietin protein Actin PF00022.19 CRK22189.1 - 9.5e-23 80.4 0.0 1e-22 80.3 0.0 1.0 1 0 0 1 1 1 1 Actin PUF PF00806.19 CRK22204.1 - 3.8e-19 67.2 0.1 1.3e-09 37.1 0.0 2.3 2 0 0 2 2 2 2 Pumilio-family RNA binding repeat Tap-RNA_bind PF09162.10 CRK22204.1 - 0.13 12.2 0.1 0.15 11.9 0.1 1.2 1 0 0 1 1 1 0 Tap, RNA-binding DUF1992 PF09350.10 CRK22209.1 - 2.1e-10 40.6 0.0 4.2e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) MFS_1 PF07690.16 CRK22210.1 - 7e-22 77.8 30.6 7e-22 77.8 30.6 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 CRK22210.1 - 2.4e-10 40.3 6.6 2.4e-10 40.3 6.6 2.7 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1_like PF12832.7 CRK22210.1 - 0.0012 17.8 5.8 0.0012 17.8 5.8 2.0 1 1 1 2 2 2 1 MFS_1 like family DUF981 PF06168.11 CRK22210.1 - 0.017 15.1 0.9 0.017 15.1 0.9 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF981) RasGEF PF00617.19 CRK22211.1 - 3.3e-51 174.0 0.0 7.9e-51 172.8 0.0 1.7 1 0 0 1 1 1 1 RasGEF domain SH3_9 PF14604.6 CRK22211.1 - 2e-06 27.5 0.0 4.9e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CRK22211.1 - 6.6e-05 22.4 0.0 0.00013 21.5 0.0 1.6 1 0 0 1 1 1 1 SH3 domain RasGEF_N PF00618.20 CRK22211.1 - 0.0015 18.7 0.3 0.005 17.1 0.0 2.0 2 0 0 2 2 2 1 RasGEF N-terminal motif Jacalin PF01419.17 CRK22212.1 - 0.00032 20.6 0.0 0.00053 19.9 0.0 1.3 1 0 0 1 1 1 1 Jacalin-like lectin domain DUF2183 PF09949.9 CRK22215.1 - 1.7e-32 111.7 0.1 7.9e-32 109.5 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) SOR_SNZ PF01680.17 CRK22223.1 - 0.14 11.9 0.1 0.24 11.2 0.1 1.3 1 0 0 1 1 1 0 SOR/SNZ family Carb_kinase PF01256.17 CRK22223.1 - 0.19 11.2 0.0 0.29 10.6 0.0 1.2 1 0 0 1 1 1 0 Carbohydrate kinase adh_short_C2 PF13561.6 CRK22225.1 - 5.8e-46 156.9 0.2 9.5e-46 156.2 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRK22225.1 - 1e-38 132.8 0.1 1.5e-38 132.2 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Asp PF00026.23 CRK22225.1 - 4.3e-13 49.4 0.0 3.1e-09 36.7 0.0 2.2 1 1 0 2 2 2 2 Eukaryotic aspartyl protease KR PF08659.10 CRK22225.1 - 6e-11 42.6 0.7 1.1e-10 41.7 0.7 1.3 1 0 0 1 1 1 1 KR domain TAXi_N PF14543.6 CRK22225.1 - 0.00085 19.6 0.7 0.057 13.7 0.0 2.9 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal ABC_tran PF00005.27 CRK22226.1 - 4.9e-45 153.4 0.0 2.1e-26 93.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 CRK22226.1 - 1.4e-39 136.4 24.9 1.5e-18 67.4 12.4 3.4 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.19 CRK22226.1 - 9e-12 44.9 0.1 0.00038 20.0 0.0 4.1 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CRK22226.1 - 1.8e-06 28.6 0.2 0.00055 20.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CRK22226.1 - 4.9e-06 26.2 1.3 0.027 14.2 0.4 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 CRK22226.1 - 8e-06 26.2 0.0 0.11 12.7 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_21 PF13304.6 CRK22226.1 - 1.2e-05 25.3 2.1 0.053 13.3 0.2 3.8 3 1 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 CRK22226.1 - 0.00019 21.9 1.0 0.85 10.0 0.0 3.0 3 0 0 3 3 2 2 AAA ATPase domain DUF87 PF01935.17 CRK22226.1 - 0.00043 20.5 0.6 0.0065 16.6 0.3 2.3 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_25 PF13481.6 CRK22226.1 - 0.0007 19.2 1.2 0.033 13.8 0.3 2.9 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 CRK22226.1 - 0.00082 18.5 0.1 1.3 8.0 0.4 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein cobW PF02492.19 CRK22226.1 - 0.0009 18.9 0.1 0.22 11.1 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 CRK22226.1 - 0.0009 19.2 0.0 0.79 9.6 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase NACHT PF05729.12 CRK22226.1 - 0.0027 17.7 1.7 1.4 8.8 0.3 2.7 2 0 0 2 2 2 2 NACHT domain MMR_HSR1 PF01926.23 CRK22226.1 - 0.0054 16.8 0.0 2.1 8.4 0.0 3.1 3 0 0 3 3 3 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 CRK22226.1 - 0.0061 15.9 0.2 0.5 9.7 0.1 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family Dynamin_N PF00350.23 CRK22226.1 - 0.02 15.0 0.2 2.2 8.3 0.1 2.5 2 0 0 2 2 2 0 Dynamin family SbcCD_C PF13558.6 CRK22226.1 - 0.021 15.1 0.8 2.2 8.6 0.0 3.3 3 0 0 3 3 2 0 Putative exonuclease SbcCD, C subunit NB-ARC PF00931.22 CRK22226.1 - 0.053 12.7 0.2 6.1 6.0 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain Zeta_toxin PF06414.12 CRK22226.1 - 0.059 12.6 0.1 7.4 5.8 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin IstB_IS21 PF01695.17 CRK22226.1 - 0.067 12.9 0.3 3 7.5 0.0 3.3 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_19 PF13245.6 CRK22226.1 - 0.086 13.2 0.1 20 5.5 0.0 3.5 3 0 0 3 3 3 0 AAA domain ATPase_2 PF01637.18 CRK22226.1 - 0.095 12.6 0.1 0.89 9.4 0.0 2.5 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea AAA_18 PF13238.6 CRK22226.1 - 0.12 12.9 0.0 34 5.0 0.0 3.3 3 0 0 3 3 3 0 AAA domain Spc7 PF08317.11 CRK22226.1 - 0.14 11.0 0.6 0.22 10.4 0.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein AAA PF00004.29 CRK22226.1 - 0.15 12.5 0.0 15 6.0 0.0 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATP-synt_ab PF00006.25 CRK22226.1 - 0.23 11.1 0.0 3.5 7.2 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF2075 PF09848.9 CRK22226.1 - 0.24 10.6 0.7 9.7 5.3 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PduV-EutP PF10662.9 CRK22226.1 - 0.3 10.8 1.0 4.4 7.0 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.6 CRK22226.1 - 0.89 9.2 3.5 46 3.7 1.8 3.0 2 1 0 2 2 2 0 AAA domain Phage_holin_2_3 PF16080.5 CRK22226.1 - 1.3 8.9 4.4 1.1 9.0 0.2 2.7 2 0 0 2 2 2 0 Bacteriophage holin family HP1 Zip PF02535.22 CRK22227.1 - 1.1e-46 159.6 3.9 1.4e-46 159.3 3.9 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Cnn_1N PF07989.11 CRK22229.1 - 1.4e-07 31.5 7.8 4.3e-07 30.0 7.8 1.8 1 0 0 1 1 1 1 Centrosomin N-terminal motif 1 Fungal_trans PF04082.18 CRK22229.1 - 0.0033 16.5 0.0 0.0055 15.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK22229.1 - 0.0099 16.0 0.8 0.019 15.1 0.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RIG-I_C PF18119.1 CRK22229.1 - 0.12 12.4 1.6 0.34 10.9 1.6 1.7 1 0 0 1 1 1 0 RIG-I receptor C-terminal domain EF-hand_4 PF12763.7 CRK22230.1 - 6e-44 148.3 0.0 1.4e-43 147.1 0.0 1.5 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 CRK22230.1 - 1.2e-07 30.8 0.3 2.6e-07 29.7 0.3 1.6 1 0 0 1 1 1 1 EF hand ACBP PF00887.19 CRK22230.1 - 8.9e-06 25.8 0.6 1.3e-05 25.3 0.6 1.3 1 0 0 1 1 1 1 Acyl CoA binding protein EF-hand_7 PF13499.6 CRK22230.1 - 1.3e-05 25.6 0.0 2.1e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 CRK22230.1 - 0.00031 20.5 0.1 0.00049 19.9 0.1 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 CRK22230.1 - 0.0004 20.1 0.3 0.0011 18.8 0.3 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 CRK22230.1 - 0.012 15.1 0.2 0.02 14.4 0.2 1.4 1 0 0 1 1 1 0 EF hand MDMPI_N PF11716.8 CRK22230.1 - 0.053 14.2 0.0 0.074 13.7 0.0 1.3 1 0 0 1 1 1 0 Mycothiol maleylpyruvate isomerase N-terminal domain ATP-sulfurylase PF01747.17 CRK22232.1 - 1e-34 119.9 0.1 1.1e-34 119.8 0.1 1.0 1 0 0 1 1 1 1 ATP-sulfurylase Acetyltransf_17 PF17668.1 CRK22234.1 - 0.055 14.3 0.0 0.063 14.1 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MRP_L53 PF10780.9 CRK22234.1 - 0.059 13.6 0.2 0.11 12.7 0.2 1.5 1 0 0 1 1 1 0 39S ribosomal protein L53/MRP-L53 DUF2390 PF09523.10 CRK22256.1 - 0.032 14.5 4.8 0.032 14.5 4.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2390) DivIVA PF05103.13 CRK22256.1 - 0.037 14.1 9.3 0.054 13.6 9.2 1.4 1 1 0 1 1 1 0 DivIVA protein DUF961 PF06125.11 CRK22256.1 - 0.05 14.0 0.2 0.06 13.7 0.2 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF961) Syntaxin-6_N PF09177.11 CRK22256.1 - 0.34 11.5 9.0 0.44 11.1 9.0 1.3 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Fungal_TACC PF12709.7 CRK22256.1 - 3.7 8.1 9.7 0.81 10.2 3.8 2.3 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins Spc7 PF08317.11 CRK22256.1 - 3.7 6.3 16.3 4.3 6.1 16.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Macoilin PF09726.9 CRK22256.1 - 7.5 5.0 16.5 8 4.9 16.5 1.0 1 0 0 1 1 1 0 Macoilin family Ank_4 PF13637.6 CRK22259.1 - 1.5e-09 38.2 1.0 1.7 9.3 0.0 6.4 4 3 2 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 CRK22259.1 - 1.4e-08 34.8 5.7 1.9 9.1 0.0 6.1 6 0 0 6 6 6 3 Ankyrin repeat Ank_2 PF12796.7 CRK22259.1 - 6.5e-07 29.9 0.1 2.1 9.0 0.0 4.2 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CRK22259.1 - 0.011 16.1 1.7 30 5.1 0.0 5.1 6 1 1 7 7 7 0 Ankyrin repeats (many copies) F-box PF00646.33 CRK22259.1 - 0.03 14.2 1.3 0.042 13.7 0.3 1.8 2 0 0 2 2 2 0 F-box domain F-box_4 PF15966.5 CRK22259.1 - 0.14 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 F-box Glyco_hydro_17 PF00332.18 CRK22260.1 - 9.2e-32 110.9 0.3 4.3e-31 108.7 0.3 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 RhoGAP PF00620.27 CRK22262.1 - 2e-46 157.6 0.0 4e-46 156.6 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 CRK22262.1 - 5.1e-12 45.9 1.3 8e-12 45.3 0.6 1.8 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain CMS1 PF14617.6 CRK22263.1 - 2.2e-74 250.0 0.4 4.1e-60 203.2 0.0 2.0 2 0 0 2 2 2 2 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 CRK22263.1 - 1.6e-05 24.7 0.0 2.4e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase RRM_1 PF00076.22 CRK22264.1 - 1.9e-12 46.8 0.0 3.8e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Corazonin PF17308.2 CRK22264.1 - 0.52 10.7 0.1 0.52 10.7 0.1 2.9 2 1 1 3 3 3 0 Pro-corazonin Peptidase_S64 PF08192.11 CRK22264.1 - 2.4 6.5 11.4 3 6.2 11.4 1.3 1 0 0 1 1 1 0 Peptidase family S64 Ndc1_Nup PF09531.10 CRK22264.1 - 2.7 6.6 9.7 3.2 6.3 9.7 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup GREB1 PF15782.5 CRK22264.1 - 10 3.1 13.6 12 2.8 13.6 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RRM_1 PF00076.22 CRK22265.1 - 1.7e-12 47.0 0.0 3.7e-12 45.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ndc1_Nup PF09531.10 CRK22265.1 - 0.94 8.1 7.7 0.95 8.1 7.7 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup GREB1 PF15782.5 CRK22265.1 - 6.1 3.8 9.9 7.6 3.5 9.9 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Ras PF00071.22 CRK22266.1 - 6.5e-54 181.9 0.0 7.4e-54 181.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CRK22266.1 - 1.9e-21 76.5 0.0 2.8e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CRK22266.1 - 2.2e-06 27.3 0.0 2.9e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Sas10_Utp3 PF04000.15 CRK22267.1 - 2.9e-15 56.7 0.7 2.9e-15 56.7 0.7 2.1 2 0 0 2 2 2 1 Sas10/Utp3/C1D family DUF3619 PF12279.8 CRK22267.1 - 0.027 14.8 1.2 0.054 13.8 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) LcrG PF07216.12 CRK22267.1 - 0.12 12.3 3.3 1 9.3 0.1 2.3 1 1 1 2 2 2 0 LcrG protein H_PPase PF03030.16 CRK22267.1 - 0.16 10.5 0.0 0.2 10.3 0.0 1.1 1 0 0 1 1 1 0 Inorganic H+ pyrophosphatase Syntaxin-6_N PF09177.11 CRK22267.1 - 0.29 11.7 3.1 1.3 9.7 1.3 2.2 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DPM3 PF08285.11 CRK22267.1 - 0.43 10.8 0.0 0.43 10.8 0.0 1.9 3 0 0 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Tti2 PF10521.9 CRK22267.1 - 0.56 9.7 3.7 0.41 10.1 2.3 1.5 2 0 0 2 2 2 0 Tti2 family DUF2076 PF09849.9 CRK22268.1 - 0.0003 20.9 19.6 0.00068 19.8 19.5 1.5 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 CRK22268.1 - 0.00048 20.2 6.2 0.00068 19.7 6.2 1.2 1 0 0 1 1 1 1 CHCH domain RskA PF10099.9 CRK22268.1 - 0.0021 18.4 5.8 0.0026 18.1 5.8 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Trypan_glycop_C PF10659.9 CRK22268.1 - 0.013 15.9 2.7 0.019 15.4 2.7 1.2 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein C-terminal domain CX9C PF16860.5 CRK22268.1 - 0.13 12.3 4.7 0.2 11.7 4.7 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, COX17 PF05051.13 CRK22268.1 - 0.27 11.6 1.4 0.7 10.3 0.1 2.0 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) UBX PF00789.20 CRK22269.1 - 2.5e-11 43.6 0.0 4.5e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 UBX domain G0-G1_switch_2 PF15103.6 CRK22269.1 - 0.00049 20.5 6.8 0.0044 17.4 0.0 2.5 2 0 0 2 2 2 1 G0/G1 switch protein 2 Thioredoxin_7 PF13899.6 CRK22269.1 - 0.066 13.4 0.0 0.22 11.7 0.0 1.9 1 0 0 1 1 1 0 Thioredoxin-like Nucleo_P87 PF07267.11 CRK22269.1 - 2.6 6.8 11.9 4.4 6.0 11.9 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 TFIIA PF03153.13 CRK22269.1 - 3.2 7.7 10.6 0.11 12.4 4.2 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit LapA_dom PF06305.11 CRK22269.1 - 9.5 6.1 5.6 7 6.5 0.2 2.6 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain SURF1 PF02104.15 CRK22270.1 - 8.2e-47 159.7 0.1 1.1e-46 159.3 0.1 1.1 1 0 0 1 1 1 1 SURF1 family CENP-T_C PF15511.6 CRK22271.1 - 4.8e-22 78.1 0.0 5.4e-15 55.4 0.0 2.4 1 1 1 2 2 2 2 Centromere kinetochore component CENP-T histone fold APH PF01636.23 CRK22272.1 - 2e-10 41.0 0.1 3.5e-10 40.2 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family zf-AN1 PF01428.16 CRK22272.1 - 0.0004 20.5 5.5 0.00068 19.8 5.5 1.4 1 0 0 1 1 1 1 AN1-like Zinc finger Haspin_kinase PF12330.8 CRK22272.1 - 0.052 12.5 0.0 0.075 12.0 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain CDH-cyt PF16010.5 CRK22273.1 - 4.6e-51 173.1 0.1 6.4e-51 172.6 0.1 1.2 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase GMC_oxred_N PF00732.19 CRK22273.1 - 3.2e-09 36.6 0.0 4.9e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 CRK22273.1 - 3.5e-06 26.4 0.1 5.6e-06 25.7 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 CRK22273.1 - 5.4e-06 26.5 0.1 1.8e-05 24.9 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 CRK22273.1 - 9.2e-06 24.6 0.1 1.3e-05 24.1 0.1 1.1 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 CRK22273.1 - 1.7e-05 24.3 0.4 3e-05 23.4 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 CRK22273.1 - 8.2e-05 22.0 0.0 0.00013 21.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CRK22273.1 - 0.00024 20.8 0.1 0.0004 20.1 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 CRK22273.1 - 0.001 18.4 0.1 0.0015 17.9 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CRK22273.1 - 0.0013 18.2 0.5 0.0018 17.7 0.5 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 CRK22273.1 - 0.0033 16.5 0.0 0.0055 15.8 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.22 CRK22273.1 - 0.016 14.3 0.0 0.023 13.8 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.17 CRK22273.1 - 0.026 13.7 0.1 0.026 13.7 0.1 1.7 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.27 CRK22273.1 - 0.091 13.3 0.1 0.16 12.5 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pro_dh PF01619.18 CRK22274.1 - 2.7e-60 204.4 0.0 3.3e-60 204.1 0.0 1.1 1 0 0 1 1 1 1 Proline dehydrogenase Aldedh PF00171.22 CRK22275.1 - 1.1e-93 314.2 0.0 1.5e-93 313.8 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family P5CR_dimer PF14748.6 CRK22275.1 - 5.2e-27 94.1 3.7 5.4e-27 94.1 1.7 2.2 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 CRK22275.1 - 2.4e-09 37.7 0.1 7.9e-09 36.0 0.1 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent DAO PF01266.24 CRK22276.1 - 3.2e-33 115.8 0.0 3.7e-33 115.6 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CRK22276.1 - 1.5e-05 25.1 0.0 0.00012 22.3 0.0 2.5 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CRK22276.1 - 0.0022 17.3 0.0 0.51 9.5 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CRK22276.1 - 0.0035 16.7 0.0 0.017 14.4 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CRK22276.1 - 0.018 14.1 0.0 0.12 11.4 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain TrkA_N PF02254.18 CRK22276.1 - 0.028 14.7 0.0 0.055 13.7 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_9 PF13454.6 CRK22276.1 - 0.037 14.0 0.0 0.087 12.8 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Thi4 PF01946.17 CRK22276.1 - 0.17 11.1 0.0 0.36 10.0 0.0 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_7 PF13241.6 CRK22276.1 - 0.19 12.2 0.0 0.38 11.2 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding FAD_binding_3 PF01494.19 CRK22276.1 - 0.2 10.8 0.0 0.36 10.0 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Zn_clus PF00172.18 CRK22277.1 - 3.3e-07 30.3 9.9 5.2e-07 29.7 9.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aa_trans PF01490.18 CRK22278.1 - 1.4e-41 142.6 34.4 1.6e-41 142.4 34.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF5336 PF17270.2 CRK22278.1 - 0.52 9.9 6.8 0.087 12.4 2.2 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5336) DUF4059 PF13268.6 CRK22278.1 - 0.7 10.3 6.9 7.8 7.0 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4059) UPF0139 PF03669.13 CRK22278.1 - 3 7.8 6.9 0.33 10.8 1.2 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0139) GFA PF04828.14 CRK22279.1 - 2.2e-15 56.8 0.0 3.2e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme SLATT_fungal PF18142.1 CRK22280.1 - 1.2e-24 86.6 0.8 1.7e-24 86.1 0.8 1.1 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain Aldo_ket_red PF00248.21 CRK22281.1 - 2.5e-63 214.0 0.0 3e-63 213.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Lipase_GDSL_2 PF13472.6 CRK22282.1 - 9e-21 75.1 0.1 1.4e-20 74.4 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 CRK22282.1 - 1.6e-09 38.1 0.0 1.9e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 CRK22282.1 - 7.4e-07 29.5 0.0 1.5e-06 28.5 0.0 1.5 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Pkinase PF00069.25 CRK22283.1 - 5.3e-58 196.4 0.0 6.1e-57 193.0 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK22283.1 - 1.3e-26 93.4 0.1 2.6e-20 72.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 CRK22283.1 - 7.6e-05 21.8 0.0 0.00012 21.1 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CRK22283.1 - 0.0003 20.8 1.9 0.039 13.9 0.2 2.9 2 1 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 CRK22283.1 - 0.00071 19.0 0.0 0.0018 17.6 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CRK22283.1 - 0.0014 18.1 0.9 0.0018 17.6 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 CRK22283.1 - 0.057 12.5 0.0 0.097 11.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 CRK22283.1 - 0.21 11.2 0.7 0.94 9.0 0.0 2.1 2 0 0 2 2 2 0 RIO1 family Peptidase_M16_M PF16187.5 CRK22285.1 - 2.6e-31 108.9 0.0 2.9e-31 108.8 0.0 1.0 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Med16 PF11635.8 CRK22310.1 - 2.2e-08 32.5 0.0 2.2e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 Mediator complex subunit 16 ATP-synt_G PF04718.15 CRK22312.1 - 3.7e-19 69.4 0.1 4.1e-19 69.3 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase g subunit Sugar_tr PF00083.24 CRK22313.1 - 1e-40 140.0 18.4 1.6e-40 139.4 18.4 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK22313.1 - 1.5e-16 60.3 35.1 3e-13 49.4 23.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 CRK22315.1 - 0.00017 20.7 0.1 0.00027 20.1 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK22315.1 - 0.00024 21.2 7.4 0.00044 20.3 7.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SH3_1 PF00018.28 CRK22316.1 - 4.4e-06 26.2 0.3 1.1e-05 25.0 0.0 1.9 2 0 0 2 2 2 1 SH3 domain SH3_16 PF18348.1 CRK22316.1 - 0.074 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial dipeptidyl-peptidase Sh3 domain SH3_9 PF14604.6 CRK22316.1 - 0.09 12.7 0.1 0.36 10.7 0.0 2.1 2 0 0 2 2 2 0 Variant SH3 domain Sclerostin PF05463.11 CRK22316.1 - 0.21 11.3 0.0 0.21 11.3 0.0 2.6 3 0 0 3 3 3 0 Sclerostin (SOST) Aminotran_1_2 PF00155.21 CRK22317.1 - 6.5e-63 213.1 0.0 8.3e-63 212.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 CRK22317.1 - 0.12 11.7 0.0 0.2 10.9 0.0 1.4 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Tmemb_18A PF09771.9 CRK22317.1 - 0.2 12.0 0.0 0.36 11.2 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 188 Aldedh PF00171.22 CRK22318.1 - 8.5e-130 433.3 5.0 3.5e-104 348.9 0.1 4.0 2 1 2 4 4 4 4 Aldehyde dehydrogenase family GMC_oxred_N PF00732.19 CRK22319.1 - 3.1e-51 174.5 0.0 4.2e-51 174.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CRK22319.1 - 2.4e-38 131.9 0.0 3.9e-38 131.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 CRK22319.1 - 1.5e-06 27.6 0.1 0.038 13.1 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 CRK22319.1 - 7.5e-06 25.2 0.0 1.1e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 CRK22319.1 - 3.5e-05 23.5 1.1 0.0013 18.4 0.1 2.8 3 1 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CRK22319.1 - 4.5e-05 23.6 0.1 0.00025 21.2 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CRK22319.1 - 0.00073 18.9 0.1 0.018 14.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 CRK22319.1 - 0.0081 15.1 0.0 0.015 14.2 0.0 1.3 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox PF00070.27 CRK22319.1 - 0.012 16.2 0.1 2.3 8.9 0.0 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CRK22319.1 - 0.024 14.0 0.1 0.8 9.0 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase SAM_2 PF07647.17 CRK22320.1 - 1.7e-34 117.7 0.0 8.9e-16 57.8 0.0 2.4 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 CRK22320.1 - 2.5e-31 107.9 0.0 4.1e-14 52.8 0.0 2.5 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) RA PF00788.23 CRK22320.1 - 5.5e-11 43.0 0.0 1.5e-10 41.6 0.0 1.7 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_4 PF18017.1 CRK22320.1 - 4e-10 39.5 0.0 0.0014 18.5 0.0 2.3 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) DUF1319 PF07028.11 CRK22320.1 - 0.002 18.3 0.7 2.8 8.2 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1319) Laminin_I PF06008.14 CRK22320.1 - 0.0065 16.2 0.8 3.4 7.3 0.1 2.2 2 0 0 2 2 2 2 Laminin Domain I DUF4950 PF16308.5 CRK22320.1 - 0.059 13.4 0.0 16 5.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4950) Glu-tRNAGln PF02686.15 CRK22320.1 - 0.089 13.1 4.7 6.9 7.0 0.4 2.5 2 0 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit TPR_22 PF18833.1 CRK22320.1 - 0.14 12.3 0.0 33 4.7 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat COG5 PF10392.9 CRK22320.1 - 0.21 11.8 1.6 24 5.1 0.1 2.5 2 0 0 2 2 2 0 Golgi transport complex subunit 5 PI3K_P85_iSH2 PF16454.5 CRK22320.1 - 0.32 10.6 1.3 21 4.6 0.1 2.2 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Rootletin PF15035.6 CRK22320.1 - 0.33 10.9 2.6 18 5.3 0.2 2.3 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Golgin_A5 PF09787.9 CRK22320.1 - 0.67 9.4 3.6 14 5.0 0.3 2.1 2 0 0 2 2 2 0 Golgin subfamily A member 5 DUF4587 PF15248.6 CRK22320.1 - 0.9 10.4 2.4 66 4.4 0.1 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4587) CENP-B_dimeris PF09026.10 CRK22320.1 - 1.9 8.9 13.2 8.4 6.8 13.2 2.1 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Sigma54_DBD PF04552.13 CRK22320.1 - 2.1 8.0 4.8 21 4.8 0.4 2.3 2 0 0 2 2 2 0 Sigma-54, DNA binding domain DUF484 PF04340.12 CRK22320.1 - 2.3 7.8 7.5 11 5.6 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF484 Chs7 PF12271.8 CRK22322.1 - 2.7e-123 410.9 12.4 3.1e-123 410.7 12.4 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone Chs7 PF12271.8 CRK22323.1 - 1.3e-105 352.9 9.6 1.9e-105 352.3 9.6 1.2 1 0 0 1 1 1 1 Chitin synthase export chaperone Cwf_Cwc_15 PF04889.12 CRK22323.1 - 0.09 12.5 4.5 0.13 12.0 4.5 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF3246 PF11596.8 CRK22323.1 - 0.31 10.5 3.3 0.54 9.7 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) PBP1_TM PF14812.6 CRK22323.1 - 0.97 9.8 6.6 2 8.8 6.6 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.10 CRK22323.1 - 5.7 7.4 10.4 12 6.3 10.4 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Cyclin PF08613.11 CRK22324.1 - 1.3e-13 51.6 0.3 3e-13 50.5 0.3 1.6 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 CRK22324.1 - 0.0068 16.2 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Spt20 PF12090.8 CRK22324.1 - 2.3 7.8 16.3 4.3 6.9 16.3 1.3 1 0 0 1 1 1 0 Spt20 family DUF2802 PF10975.8 CRK22324.1 - 4.4 7.5 7.2 9.8 6.4 7.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) Apt1 PF10351.9 CRK22325.1 - 0.035 13.0 2.0 0.041 12.7 2.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain AAA PF00004.29 CRK22326.1 - 4.9e-08 33.5 0.7 6.5e-07 29.8 0.7 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 CRK22326.1 - 0.00055 19.9 0.1 0.019 14.9 0.0 2.8 3 0 0 3 3 3 1 Rad17 P-loop domain AAA_16 PF13191.6 CRK22326.1 - 0.016 15.6 0.0 0.045 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain TIP49 PF06068.13 CRK22326.1 - 0.019 14.2 0.0 0.03 13.5 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_18 PF13238.6 CRK22326.1 - 0.029 14.9 0.0 0.071 13.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CRK22326.1 - 0.042 14.1 0.1 0.24 11.7 0.1 2.1 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 CRK22326.1 - 0.19 11.8 0.0 0.35 10.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 CRK22326.1 - 0.2 10.7 0.0 0.35 9.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Utp8 PF10395.9 CRK22327.1 - 0.012 14.1 0.0 0.022 13.3 0.0 1.3 1 0 0 1 1 1 0 Utp8 family Rib_5-P_isom_A PF06026.14 CRK22329.1 - 0.00047 19.8 0.0 0.00062 19.4 0.0 1.2 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Sugar-bind PF04198.13 CRK22329.1 - 0.13 11.4 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 Putative sugar-binding domain DeoRC PF00455.22 CRK22329.1 - 0.17 11.8 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 DeoR C terminal sensor domain TRI12 PF06609.13 CRK22333.1 - 2.9e-18 65.6 5.2 3.5e-18 65.4 5.2 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) AzlD PF05437.12 CRK22333.1 - 0.017 15.3 0.1 0.017 15.3 0.1 2.1 2 0 0 2 2 2 0 Branched-chain amino acid transport protein (AzlD) Transp_inhibit PF18791.1 CRK22333.1 - 0.068 12.7 0.2 0.13 11.7 0.2 1.5 1 0 0 1 1 1 0 Transport inhibitor response 1 protein domain DUF3784 PF12650.7 CRK22333.1 - 0.28 11.4 5.8 0.11 12.7 0.8 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF3784) Pox_A14 PF05767.12 CRK22333.1 - 2.4 8.4 6.5 2.2 8.5 3.7 2.0 1 1 1 2 2 2 0 Poxvirus virion envelope protein A14 Enolase_N PF03952.16 CRK22356.1 - 2.1e-57 192.9 0.1 2.5e-57 192.7 0.1 1.0 1 0 0 1 1 1 1 Enolase, N-terminal domain Enolase_C PF00113.22 CRK22356.1 - 3.7e-12 46.1 0.1 6.1e-12 45.4 0.1 1.4 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain ArfGap PF01412.18 CRK22363.1 - 4.2e-33 113.9 0.0 6.7e-33 113.2 0.0 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Pkinase PF00069.25 CRK22364.1 - 7.3e-62 209.1 0.0 1.2e-61 208.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK22364.1 - 5.4e-29 101.3 0.0 8.5e-29 100.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 CRK22364.1 - 1.1e-16 60.9 0.1 2.5e-16 59.8 0.1 1.6 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 CRK22364.1 - 3.4e-08 33.1 0.0 5.1e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Yop-YscD_cpl PF16697.5 CRK22364.1 - 2.1e-07 31.2 0.0 4.7e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Pkinase_fungal PF17667.1 CRK22364.1 - 4.2e-06 25.8 0.0 6.7e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CRK22364.1 - 7.6e-06 25.4 0.3 1.9e-05 24.1 0.1 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 CRK22364.1 - 0.067 12.1 0.1 0.1 11.6 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase YrbL-PhoP_reg PF10707.9 CRK22364.1 - 0.087 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.23 CRK22364.1 - 0.19 11.6 0.0 5.9 6.7 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family ADK PF00406.22 CRK22365.1 - 1.3e-31 109.7 0.2 7.9e-17 61.8 0.0 2.2 1 1 1 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 CRK22365.1 - 3.5e-27 95.5 0.2 2.9e-15 56.9 0.1 2.2 1 1 1 2 2 2 2 AAA domain AAA_33 PF13671.6 CRK22365.1 - 5.7e-05 23.3 0.4 0.029 14.5 0.1 2.4 1 1 0 2 2 2 2 AAA domain AAA_18 PF13238.6 CRK22365.1 - 0.00014 22.4 0.2 0.13 12.8 0.1 2.2 1 1 1 2 2 2 2 AAA domain Thymidylate_kin PF02223.17 CRK22365.1 - 0.096 12.4 0.4 5 6.8 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase Pro_isomerase PF00160.21 CRK22366.1 - 5.8e-50 169.6 0.0 1.2e-49 168.6 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 CRK22366.1 - 6.3e-11 42.7 0.0 0.00083 20.1 0.0 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK22366.1 - 0.0003 21.0 0.0 0.22 11.9 0.0 2.7 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CRK22366.1 - 0.044 12.7 0.7 1.5 7.7 0.1 2.7 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Calreticulin PF00262.18 CRK22367.1 - 3.2e-165 549.4 17.3 4.2e-165 549.0 17.3 1.1 1 0 0 1 1 1 1 Calreticulin family tRNA_anti-like PF12869.7 CRK22367.1 - 7.8 6.1 7.8 17 5.0 0.6 3.2 3 0 0 3 3 3 0 tRNA_anti-like Aldolase_II PF00596.21 CRK22368.1 - 1.1e-43 149.4 0.0 3.3e-43 147.8 0.0 1.7 2 0 0 2 2 2 1 Class II Aldolase and Adducin N-terminal domain MRP_L53 PF10780.9 CRK22369.1 - 1.8e-19 69.7 0.8 2.9e-19 69.0 0.8 1.4 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 Ecotin PF03974.13 CRK22369.1 - 0.11 12.5 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Ecotin Pyrophosphatase PF00719.19 CRK22370.1 - 1.5e-56 190.7 0.2 1.9e-56 190.3 0.2 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase SAP130_C PF16014.5 CRK22370.1 - 4.3 6.3 10.5 7.3 5.6 10.5 1.4 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus MSP1_C PF07462.11 CRK22370.1 - 5.8 5.5 6.4 4.1 6.0 0.0 2.1 2 0 0 2 2 2 0 Merozoite surface protein 1 (MSP1) C-terminus Dus PF01207.17 CRK22371.1 - 4.2e-40 137.7 0.2 2.7e-39 135.1 0.2 1.9 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) ApoO PF09769.9 CRK22372.1 - 3.6e-39 133.7 1.7 2.2e-38 131.1 0.1 2.4 3 0 0 3 3 3 1 Apolipoprotein O Peptidase_M3 PF01432.20 CRK22373.1 - 2.5e-118 396.2 0.0 3.4e-118 395.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 CRK22373.1 - 0.01 15.5 0.2 0.017 14.8 0.2 1.3 1 0 0 1 1 1 0 Peptidase M50B-like Lipase_GDSL_2 PF13472.6 CRK22375.1 - 2.7e-21 76.8 3.9 4.2e-21 76.2 3.9 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 CRK22375.1 - 9.4e-08 32.3 0.0 1.6e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase BOP1NT PF08145.12 CRK22376.1 - 1.6e-104 349.5 9.3 2.1e-104 349.1 9.3 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 CRK22376.1 - 2.4e-24 85.2 4.1 1e-11 45.2 0.2 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK22376.1 - 3.8e-07 30.3 0.2 0.0024 18.1 0.0 3.9 3 3 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 CRK22376.1 - 0.00094 17.6 0.0 2.2 6.5 0.0 3.0 2 1 1 3 3 3 3 WD repeat-containing and planar cell polarity effector protein Fritz Zn_clus PF00172.18 CRK22377.1 - 7.6e-05 22.8 11.2 0.00015 21.8 11.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1416 PF07210.12 CRK22377.1 - 0.049 13.5 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1416) MARVEL PF01284.23 CRK22378.1 - 2.6e-15 56.7 14.6 3.2e-15 56.4 14.6 1.0 1 0 0 1 1 1 1 Membrane-associating domain Glyco_transf_21 PF13506.6 CRK22378.1 - 0.0017 17.8 0.0 0.0025 17.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 AMP-binding PF00501.28 CRK22380.1 - 3.2e-89 299.4 0.0 4e-89 299.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme PsiB PF06290.11 CRK22380.1 - 0.15 11.5 0.0 0.33 10.4 0.0 1.5 1 0 0 1 1 1 0 Plasmid SOS inhibition protein (PsiB) Zn_clus PF00172.18 CRK22381.1 - 0.0076 16.3 14.1 0.069 13.3 14.1 2.3 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Herpes_capsid PF06112.11 CRK22381.1 - 4.3 7.4 10.0 8.7 6.4 10.0 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Beta-lactamase PF00144.24 CRK22382.1 - 3.6e-42 144.8 0.0 5.9e-42 144.1 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase FMO-like PF00743.19 CRK22383.1 - 1.6e-20 73.1 0.3 3.1e-16 58.9 0.0 2.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 CRK22383.1 - 7.7e-13 48.3 0.0 5.8e-11 42.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CRK22383.1 - 2.6e-10 40.0 0.0 1.1e-09 37.9 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 CRK22383.1 - 6.2e-10 38.8 0.0 2e-09 37.1 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CRK22383.1 - 7.1e-08 32.6 0.0 1.7e-06 28.2 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 CRK22383.1 - 0.0011 19.5 0.1 1.5 9.4 0.0 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CRK22383.1 - 0.011 15.7 1.4 14 5.7 0.0 4.1 4 0 0 4 4 4 0 FAD-NAD(P)-binding Shikimate_DH PF01488.20 CRK22383.1 - 0.016 15.2 0.1 3.5 7.7 0.0 2.6 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase DAO PF01266.24 CRK22383.1 - 0.026 14.1 0.7 1.1 8.8 0.0 2.8 2 1 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 CRK22383.1 - 0.035 12.8 0.2 0.6 8.7 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.24 CRK22383.1 - 0.059 12.4 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 CRK22383.1 - 0.11 11.5 0.6 0.27 10.2 0.1 1.9 2 1 0 2 2 2 0 Lycopene cyclase protein ThiF PF00899.21 CRK22383.1 - 0.14 11.5 0.0 14 4.9 0.0 2.9 3 0 0 3 3 3 0 ThiF family WD40 PF00400.32 CRK22384.1 - 0.0058 17.5 17.4 1.5 9.8 0.2 6.2 7 0 0 7 7 7 3 WD domain, G-beta repeat DUF3987 PF13148.6 CRK22384.1 - 0.067 12.2 0.2 0.11 11.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) CTD_bind PF04818.13 CRK22385.1 - 6.5e-10 39.7 0.0 1.9e-09 38.2 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase II-binding domain. PUA PF01472.20 CRK22386.1 - 2e-14 53.3 0.0 2.8e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 PUA domain TAP42 PF04177.12 CRK22387.1 - 9.1e-16 57.9 0.0 1e-15 57.7 0.0 1.0 1 0 0 1 1 1 1 TAP42-like family AAA_7 PF12775.7 CRK22416.1 - 1e-14 54.5 0.0 1.6e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region T2SSE PF00437.20 CRK22416.1 - 5.3e-05 22.4 0.0 5.8e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 CRK22416.1 - 6.3e-05 23.3 0.0 0.00011 22.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CRK22416.1 - 0.00036 20.6 0.0 0.00067 19.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 CRK22416.1 - 0.00096 19.6 0.0 0.0016 18.9 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 CRK22416.1 - 0.0027 18.0 0.0 0.0043 17.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 CRK22416.1 - 0.0032 17.1 0.0 0.0043 16.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CRK22416.1 - 0.0053 16.6 0.1 0.021 14.6 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 CRK22416.1 - 0.0061 16.7 0.0 0.0099 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 CRK22416.1 - 0.0074 15.7 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 CRK22416.1 - 0.0086 15.8 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 CRK22416.1 - 0.01 16.4 0.0 0.016 15.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 CRK22416.1 - 0.059 13.3 0.0 0.077 12.9 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain FANCM-MHF_bd PF16783.5 CRK22416.1 - 0.079 13.0 0.1 0.13 12.3 0.1 1.3 1 0 0 1 1 1 0 FANCM to MHF binding domain AAA_24 PF13479.6 CRK22416.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CRK22416.1 - 0.18 12.1 0.0 0.27 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain CTP_transf_1 PF01148.20 CRK22460.1 - 5.1e-12 46.1 12.4 6.9e-12 45.7 12.4 1.2 1 0 0 1 1 1 1 Cytidylyltransferase family TPR_10 PF13374.6 CRK22477.1 - 4e-22 77.4 0.0 0.0012 18.7 0.0 7.3 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_12 PF13424.6 CRK22477.1 - 6.6e-20 71.2 0.8 8.6e-06 26.0 0.1 6.7 4 1 3 7 7 7 5 Tetratricopeptide repeat NB-ARC PF00931.22 CRK22477.1 - 0.0037 16.5 0.0 0.32 10.1 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain AAA_22 PF13401.6 CRK22477.1 - 0.022 15.0 0.0 0.13 12.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF3293 PF11697.8 CRK22477.1 - 0.44 11.1 1.9 9.8 6.7 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3293) TPR_19 PF14559.6 CRK22477.1 - 0.74 10.4 2.7 8.3 7.0 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Pkinase PF00069.25 CRK22479.1 - 1.4e-07 31.2 0.0 2.2e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 CRK22479.1 - 0.00014 21.3 0.0 0.00024 20.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CRK22479.1 - 0.0013 18.8 0.1 0.0027 17.7 0.1 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family 2OG-FeII_Oxy_3 PF13640.6 CRK22481.1 - 0.13 13.2 0.0 0.21 12.5 0.0 1.3 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Aldedh PF00171.22 CRK22483.1 - 1.2e-111 373.5 0.1 1.5e-98 330.3 0.0 2.3 1 1 1 2 2 2 2 Aldehyde dehydrogenase family Amino_oxidase PF01593.24 CRK22483.1 - 1.1e-53 183.2 0.0 1.7e-53 182.5 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CRK22483.1 - 3.5e-13 49.6 0.2 1.1e-12 48.0 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain BTB PF00651.31 CRK22483.1 - 4.1e-10 39.9 0.0 3.6e-09 36.8 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain FAD_binding_2 PF00890.24 CRK22483.1 - 4.3e-08 32.7 1.3 6.8e-08 32.0 1.3 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 CRK22483.1 - 5.9e-08 32.5 0.7 1e-07 31.7 0.4 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 CRK22483.1 - 3.4e-06 26.5 0.3 7.3e-06 25.4 0.3 1.6 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 CRK22483.1 - 6.9e-06 25.0 0.4 1.4e-05 24.0 0.4 1.5 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 CRK22483.1 - 7.9e-06 25.7 2.0 1.8e-05 24.5 1.8 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CRK22483.1 - 0.00011 21.6 0.5 0.00063 19.1 0.1 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CRK22483.1 - 0.00016 20.9 0.5 0.00048 19.3 0.3 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.27 CRK22483.1 - 0.00046 20.7 0.7 0.0017 18.9 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CRK22483.1 - 0.00048 19.5 0.4 0.01 15.1 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CRK22483.1 - 0.00058 19.0 0.9 0.0096 15.0 0.9 2.6 3 0 0 3 3 3 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 CRK22483.1 - 0.028 13.7 0.7 0.072 12.4 0.7 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 CRK22483.1 - 0.13 11.5 0.3 0.23 10.7 0.3 1.4 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 CRK22483.1 - 0.25 11.3 0.7 24 4.9 0.2 3.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding N2227 PF07942.12 CRK22485.1 - 1.7e-64 217.6 0.0 8.5e-58 195.7 0.0 2.2 1 1 1 2 2 2 2 N2227-like protein Fungal_trans PF04082.18 CRK22485.1 - 5.3e-14 51.9 0.4 2.6e-13 49.6 0.4 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain adh_short_C2 PF13561.6 CRK22488.1 - 1.6e-43 149.0 0.6 2.1e-43 148.6 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRK22488.1 - 2.4e-39 134.8 0.7 2.7e-39 134.7 0.1 1.3 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 CRK22488.1 - 4.2e-11 43.1 0.3 7.7e-11 42.2 0.3 1.3 1 1 0 1 1 1 1 KR domain SPRY PF00622.28 CRK22494.1 - 3.2e-20 72.4 0.1 5.5e-20 71.7 0.1 1.4 1 0 0 1 1 1 1 SPRY domain Zn_clus PF00172.18 CRK22496.1 - 5.9e-08 32.7 11.1 9.4e-08 32.1 11.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 CRK22496.1 - 2.1e-05 23.5 0.2 4.3e-05 22.5 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain HEAT_EZ PF13513.6 CRK22499.1 - 5.1e-34 116.3 12.1 1.6e-15 57.2 0.1 10.8 10 1 2 12 12 10 3 HEAT-like repeat HEAT PF02985.22 CRK22499.1 - 5.8e-27 91.5 11.1 6.9e-06 25.9 0.0 10.4 11 0 0 11 11 10 6 HEAT repeat HEAT_2 PF13646.6 CRK22499.1 - 1.4e-20 73.5 4.5 0.00036 20.9 0.0 7.8 5 4 4 9 9 8 3 HEAT repeats MMS19_C PF12460.8 CRK22499.1 - 2.6e-15 56.5 9.1 0.00017 20.8 0.0 5.3 4 1 1 5 5 5 4 RNAPII transcription regulator C-terminal Cnd1 PF12717.7 CRK22499.1 - 4.9e-13 49.4 0.6 0.025 14.6 0.0 6.2 5 2 2 7 7 7 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 CRK22499.1 - 1.1e-09 38.8 0.0 0.0042 17.6 0.0 6.0 4 2 3 7 7 7 3 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 CRK22499.1 - 2.2e-08 33.2 0.0 0.036 12.6 0.1 4.3 2 2 1 4 4 4 2 Adaptin N terminal region CLASP_N PF12348.8 CRK22499.1 - 3e-06 27.0 0.2 2.5 7.6 0.0 5.7 5 1 0 5 5 5 2 CLASP N terminal IBN_N PF03810.19 CRK22499.1 - 2.2e-05 24.3 0.3 0.00095 19.0 0.1 3.9 2 1 0 2 2 2 1 Importin-beta N-terminal domain RTP1_C1 PF10363.9 CRK22499.1 - 2.2e-05 24.6 0.5 0.019 15.2 0.0 4.0 4 0 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 DUF3437 PF11919.8 CRK22499.1 - 0.00021 21.1 2.1 0.59 10.1 0.0 5.0 4 2 2 6 6 6 1 Domain of unknown function (DUF3437) UME PF08064.13 CRK22499.1 - 0.0027 17.6 0.0 1.3 9.0 0.0 4.5 4 2 0 4 4 4 1 UME (NUC010) domain Telomere_reg-2 PF10193.9 CRK22499.1 - 0.0055 17.1 1.7 0.43 11.0 0.1 4.0 4 0 0 4 4 4 1 Telomere length regulation protein HEAT_PBS PF03130.16 CRK22499.1 - 0.0081 16.7 0.5 31 5.7 0.1 4.7 4 0 0 4 4 3 0 PBS lyase HEAT-like repeat Arm PF00514.23 CRK22499.1 - 0.025 14.6 5.7 7.9 6.7 0.0 6.3 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat RIX1 PF08167.12 CRK22499.1 - 0.034 13.9 0.3 34 4.1 0.0 4.3 3 2 1 5 5 5 0 rRNA processing/ribosome biogenesis Gcn1_N PF12074.8 CRK22499.1 - 0.059 12.7 0.1 8.8 5.5 0.0 3.4 3 1 0 3 3 3 0 Generalcontrol nonderepressible 1 (Gcn1) N-terminal Myf5 PF12232.8 CRK22499.1 - 0.091 13.5 0.0 0.43 11.4 0.0 2.1 2 0 0 2 2 2 0 Myogenic determination factor 5 PAC4 PF16093.5 CRK22501.1 - 9.3e-22 77.0 0.1 1.2e-21 76.7 0.1 1.1 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 POC3_POC4 PF10448.9 CRK22501.1 - 0.0023 17.9 0.0 0.0026 17.8 0.0 1.4 1 1 0 1 1 1 1 20S proteasome chaperone assembly proteins 3 and 4 Homeobox_KN PF05920.11 CRK22503.1 - 2.1e-18 65.9 0.1 4.2e-18 65.0 0.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 CRK22503.1 - 9.8e-09 34.9 0.0 2.2e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 CRK22503.1 - 0.0024 17.3 0.7 0.017 14.6 0.7 2.2 1 1 1 2 2 2 1 Homeodomain leucine-zipper encoding, Homez HTH_36 PF13730.6 CRK22503.1 - 0.15 12.0 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain zf-C2H2_4 PF13894.6 CRK22503.1 - 0.24 12.3 26.9 0.13 13.1 4.4 4.8 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2 PF00096.26 CRK22503.1 - 0.37 11.3 23.6 0.5 10.9 0.6 4.7 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 CRK22503.1 - 1 9.7 8.0 11 6.4 3.7 3.2 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Peptidase_M20 PF01546.28 CRK22505.1 - 8.4e-32 110.5 0.1 2e-31 109.3 0.1 1.7 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DUF3328 PF11807.8 CRK22505.1 - 2.1e-14 53.9 0.4 5.7e-14 52.4 0.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Methyltransf_25 PF13649.6 CRK22505.1 - 0.0017 19.0 0.0 0.071 13.8 0.0 3.0 2 0 0 2 2 2 1 Methyltransferase domain M20_dimer PF07687.14 CRK22505.1 - 0.0025 17.7 0.2 0.016 15.2 0.1 2.4 2 0 0 2 2 2 1 Peptidase dimerisation domain Methyltransf_11 PF08241.12 CRK22505.1 - 0.0037 17.9 0.0 0.015 15.9 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Peptidase_M28 PF04389.17 CRK22505.1 - 0.0085 15.8 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 G-patch PF01585.23 CRK22515.1 - 1.6e-05 24.7 0.1 9.7e-05 22.2 0.1 2.1 1 1 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 CRK22515.1 - 0.0075 16.3 0.1 0.023 14.8 0.1 1.8 1 1 0 1 1 1 1 G-patch domain Tam41_Mmp37 PF09139.11 CRK22518.1 - 4e-23 82.4 0.1 4.4e-23 82.2 0.1 1.0 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial RWD PF05773.22 CRK22519.1 - 0.0027 18.0 0.0 0.0039 17.5 0.0 1.2 1 0 0 1 1 1 1 RWD domain AKNA PF12443.8 CRK22533.1 - 0.024 15.3 0.8 0.07 13.8 0.5 1.7 1 1 1 2 2 2 0 AT-hook-containing transcription factor Tox-GHH PF15636.6 CRK22533.1 - 0.05 13.6 0.0 0.069 13.1 0.0 1.2 1 0 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin FATC PF02260.20 CRK22552.1 - 0.1 12.5 0.5 0.14 12.0 0.5 1.3 1 1 0 1 1 1 0 FATC domain HEAT PF02985.22 CRK22553.1 - 7.9e-05 22.6 0.0 0.19 12.1 0.0 2.3 2 0 0 2 2 2 2 HEAT repeat HEAT_2 PF13646.6 CRK22553.1 - 0.00095 19.5 0.0 1.2 9.6 0.0 2.2 1 1 1 2 2 2 2 HEAT repeats HEAT_EZ PF13513.6 CRK22553.1 - 0.44 11.1 2.2 3.4 8.3 0.1 2.6 2 2 0 2 2 2 0 HEAT-like repeat ABC2_membrane PF01061.24 CRK22556.1 - 2.8e-48 164.1 25.2 2.8e-48 164.1 25.2 1.6 2 0 0 2 2 2 1 ABC-2 type transporter PDR_CDR PF06422.12 CRK22556.1 - 0.00033 20.5 0.1 0.00033 20.5 0.1 3.3 3 0 0 3 3 3 1 CDR ABC transporter VEK-30 PF12107.8 CRK22556.1 - 0.099 12.6 0.5 0.18 11.8 0.5 1.4 1 0 0 1 1 1 0 Plasminogen (Pg) ligand in fibrinolytic pathway AAA_21 PF13304.6 CRK22556.1 - 0.14 12.0 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 CRK22556.1 - 0.54 9.3 24.8 1.2 8.1 24.1 1.7 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF456 PF04306.13 CRK22556.1 - 2.8 8.2 11.5 5.3 7.3 7.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF456) Bac_surface_Ag PF01103.23 CRK22557.1 - 1.3e-21 77.4 0.0 1.9e-21 76.9 0.0 1.2 1 0 0 1 1 1 1 Surface antigen UQ_con PF00179.26 CRK22558.1 - 3.7e-20 72.0 0.0 5.3e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme TMEM135_C_rich PF15982.5 CRK22560.1 - 0.043 14.4 0.4 0.1 13.2 0.1 1.8 2 0 0 2 2 2 0 N-terminal cysteine-rich region of Transmembrane protein 135 SNO PF01174.19 CRK22561.1 - 3e-48 164.2 0.0 2e-47 161.5 0.0 1.9 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 CRK22561.1 - 2.9e-07 30.3 0.0 1.4e-06 28.1 0.0 1.8 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_S51 PF03575.17 CRK22561.1 - 2.2e-05 24.2 0.0 3.3e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S51 DJ-1_PfpI PF01965.24 CRK22561.1 - 0.00014 21.7 0.1 0.00024 21.0 0.1 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.28 CRK22561.1 - 0.17 11.6 0.0 2 8.2 0.0 2.0 1 1 0 1 1 1 0 Glutamine amidotransferase class-I SOR_SNZ PF01680.17 CRK22562.1 - 1.1e-102 342.2 7.4 1.5e-102 341.8 7.4 1.1 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 CRK22562.1 - 5.5e-09 35.7 8.9 2.2e-07 30.4 1.1 2.6 2 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG TetR_C_27 PF17935.1 CRK22562.1 - 0.00083 19.4 0.0 0.0033 17.5 0.0 1.9 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain Dus PF01207.17 CRK22562.1 - 0.0011 18.2 0.6 0.31 10.1 0.0 2.5 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 CRK22562.1 - 0.0017 17.8 0.7 0.057 12.9 0.0 2.6 3 0 0 3 3 3 1 Histidine biosynthesis protein NanE PF04131.14 CRK22562.1 - 0.023 13.9 0.9 0.24 10.6 0.0 2.7 1 1 1 3 3 3 0 Putative N-acetylmannosamine-6-phosphate epimerase IGPS PF00218.21 CRK22562.1 - 0.055 12.6 0.1 0.88 8.7 0.0 2.6 2 2 0 2 2 2 0 Indole-3-glycerol phosphate synthase NMO PF03060.15 CRK22562.1 - 0.78 9.1 11.5 0.16 11.4 3.3 2.2 2 0 0 2 2 2 0 Nitronate monooxygenase adh_short PF00106.25 CRK22563.1 - 5.8e-22 78.1 0.0 6.2e-19 68.2 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CRK22563.1 - 2.6e-11 43.5 0.0 1.8e-08 34.3 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK22563.1 - 6.5e-08 32.7 0.0 1.1e-07 32.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 CRK22563.1 - 0.19 10.8 0.0 0.26 10.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Pex24p PF06398.11 CRK22564.1 - 6.3e-92 308.4 0.8 7.6e-92 308.1 0.8 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin TRI12 PF06609.13 CRK22565.1 - 2.3e-58 198.1 12.3 3e-58 197.7 12.3 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 CRK22565.1 - 1.3e-20 73.7 28.5 4e-20 72.0 27.7 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Thiolase_N PF00108.23 CRK22567.1 - 4.1e-45 154.2 3.4 8.4e-26 90.9 0.1 2.2 1 1 1 2 2 2 2 Thiolase, N-terminal domain Thiolase_C PF02803.18 CRK22567.1 - 1.7e-40 137.5 0.2 4.7e-40 136.1 0.2 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain MFS_1 PF07690.16 CRK22568.1 - 3.7e-18 65.6 38.4 6e-09 35.3 4.7 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_1 PF07690.16 CRK22569.1 - 7.7e-42 143.5 24.2 7.7e-42 143.5 24.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Dynamin_N PF00350.23 CRK22570.1 - 7.7e-13 48.8 1.7 5.8e-11 42.7 0.0 3.4 2 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 CRK22570.1 - 2.2e-05 24.5 0.0 0.043 13.9 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase ABC_tran PF00005.27 CRK22570.1 - 0.00055 20.5 2.6 0.012 16.2 0.0 3.3 3 0 0 3 3 3 1 ABC transporter RsgA_GTPase PF03193.16 CRK22570.1 - 0.012 15.5 0.0 0.059 13.3 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase cobW PF02492.19 CRK22570.1 - 0.062 12.9 0.0 0.16 11.5 0.0 1.7 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF4360 PF14273.6 CRK22570.1 - 0.076 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4360) AAA_16 PF13191.6 CRK22570.1 - 0.12 12.7 0.8 0.82 10.0 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain MscS_porin PF12795.7 CRK22570.1 - 0.31 10.6 14.1 0.06 12.9 9.9 2.0 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain DUF4407 PF14362.6 CRK22570.1 - 1.7 8.0 9.1 3.8 6.8 9.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TMPIT PF07851.13 CRK22570.1 - 6.1 6.0 6.3 14 4.8 6.3 1.5 1 0 0 1 1 1 0 TMPIT-like protein SH3_9 PF14604.6 CRK22571.1 - 0.00015 21.6 1.4 0.00061 19.6 0.2 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 CRK22571.1 - 0.00018 21.1 0.1 0.00038 20.1 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CRK22571.1 - 0.016 14.8 1.2 0.033 13.8 1.2 1.5 1 0 0 1 1 1 0 SH3 domain zf-H2C2_2 PF13465.6 CRK22571.1 - 8.5 7.0 7.8 7.1 7.2 1.4 3.2 3 0 0 3 3 3 0 Zinc-finger double domain Catalase PF00199.19 CRK22572.1 - 0.00015 21.0 0.0 0.052 12.6 0.0 2.1 2 0 0 2 2 2 2 Catalase DUF755 PF05501.11 CRK22573.1 - 0.16 12.3 17.5 0.24 11.7 17.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) CoA_trans PF01144.23 CRK22574.1 - 7.6e-95 316.4 2.1 2e-58 197.3 0.0 2.1 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 CRK22574.1 - 0.004 17.1 0.3 0.0083 16.1 0.3 1.5 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Mal_decarbox_Al PF16957.5 CRK22574.1 - 0.04 12.3 0.5 0.24 9.7 0.0 1.9 2 0 0 2 2 2 0 Malonate decarboxylase, alpha subunit, transporter DALR_2 PF09190.11 CRK22575.1 - 0.021 15.3 0.1 3 8.4 0.0 2.9 3 0 0 3 3 3 0 DALR domain Mito_carr PF00153.27 CRK22576.1 - 3.1e-46 155.2 2.5 3.2e-17 62.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Zn_clus PF00172.18 CRK22577.1 - 5.6e-06 26.4 10.4 1.1e-05 25.5 10.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acetyltransf_1 PF00583.25 CRK22578.1 - 4.6e-05 23.6 0.1 0.00012 22.3 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 CRK22578.1 - 0.00015 21.6 0.0 0.00042 20.2 0.0 1.7 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 CRK22578.1 - 0.00037 20.9 0.4 0.00088 19.7 0.1 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CRK22578.1 - 0.00078 19.4 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 CRK22578.1 - 0.089 12.9 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 CRK22578.1 - 0.17 12.5 0.1 0.34 11.6 0.1 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF1989 PF09347.10 CRK22579.1 - 2.5e-54 183.4 0.0 3.4e-54 183.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) Fmp27_WPPW PF10359.9 CRK22582.1 - 4.6e-11 42.3 0.1 5.9e-11 41.9 0.1 1.1 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27 PF10344.9 CRK22582.1 - 4.5e-09 35.0 0.1 5.6e-09 34.7 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 AAA PF00004.29 CRK22594.1 - 6.4e-31 107.5 0.0 7e-31 107.4 0.0 1.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 CRK22594.1 - 0.0061 16.7 0.0 0.0072 16.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Nic96 PF04097.14 CRK22602.1 - 5e-22 78.1 0.0 5.3e-22 78.0 0.0 1.0 1 0 0 1 1 1 1 Nup93/Nic96 MFS_1 PF07690.16 CRK22603.1 - 1e-05 24.6 25.5 1.9e-05 23.8 9.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SHOCT PF09851.9 CRK22604.1 - 0.06 13.1 1.0 0.15 11.8 0.0 2.3 2 0 0 2 2 2 0 Short C-terminal domain Tudor_RapA PF18337.1 CRK22604.1 - 0.18 12.0 0.0 0.34 11.1 0.0 1.4 1 0 0 1 1 1 0 RapA N-terminal Tudor like domain Melibiase PF02065.18 CRK22605.1 - 9.6e-142 472.0 0.0 1.3e-141 471.6 0.0 1.2 1 0 0 1 1 1 1 Melibiase Glyco_hydro_36N PF16875.5 CRK22605.1 - 4.9e-82 275.3 0.0 7.9e-82 274.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 N-terminal domain Pec_lyase_C PF00544.19 CRK22605.1 - 3.8e-33 114.8 7.7 3.8e-33 114.8 7.7 2.0 2 1 0 2 2 2 1 Pectate lyase Glyco_hydro_36C PF16874.5 CRK22605.1 - 3e-18 66.1 0.0 7e-18 64.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 C-terminal domain MF_alpha_N PF05436.11 CRK22605.1 - 0.00019 21.2 0.7 0.02 14.8 0.1 2.6 2 0 0 2 2 2 1 Mating factor alpha precursor N-terminus GHL10 PF02638.15 CRK22605.1 - 0.00023 20.4 0.0 0.0004 19.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase-like 10 Hemerythrin PF01814.23 CRK22606.1 - 2.9e-11 44.1 1.3 4.9e-11 43.4 1.3 1.4 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain DUF4286 PF14114.6 CRK22606.1 - 0.31 11.6 3.0 1 9.9 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4286) ORC6 PF05460.13 CRK22607.1 - 0.0022 17.3 2.7 0.0032 16.8 2.7 1.3 1 1 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) PP1_bind PF15276.6 CRK22607.1 - 0.021 15.1 5.3 0.043 14.1 3.9 2.3 1 1 0 1 1 1 0 Protein phosphatase 1 binding Aminotran_1_2 PF00155.21 CRK22608.1 - 5.8e-69 233.0 0.0 6.7e-69 232.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 CRK22608.1 - 0.00029 20.2 0.0 0.00044 19.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 CRK22608.1 - 0.0017 17.0 0.0 0.0034 16.0 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 CRK22608.1 - 0.0019 17.6 0.0 0.005 16.2 0.0 1.6 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 CRK22608.1 - 0.016 14.2 0.0 0.033 13.1 0.0 1.5 1 1 0 1 1 1 0 Aminotransferase class-V Foie-gras_1 PF11817.8 CRK22608.1 - 0.21 11.2 0.0 0.33 10.5 0.0 1.2 1 0 0 1 1 1 0 Foie gras liver health family 1 DUF2407_C PF13373.6 CRK22609.1 - 2.4e-37 128.3 0.2 3.3e-37 127.8 0.2 1.2 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.9 CRK22609.1 - 3.4e-30 104.7 0.0 5.1e-30 104.1 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 CRK22609.1 - 6e-06 25.9 0.0 2.2e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD_2 PF13881.6 CRK22609.1 - 0.00028 21.0 0.0 0.0005 20.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like rRNA_proc-arch PF13234.6 CRK22610.1 - 2.6e-78 263.7 0.0 7.5e-78 262.2 0.0 1.8 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 CRK22610.1 - 3.2e-48 163.5 2.4 1.1e-47 161.7 2.4 2.0 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 CRK22610.1 - 1.2e-18 67.5 0.0 1e-17 64.5 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CRK22610.1 - 3.4e-08 33.8 0.0 1.2e-07 32.0 0.0 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CRK22610.1 - 8.8e-06 25.8 0.0 3.4e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CRK22610.1 - 0.083 13.2 0.1 0.53 10.5 0.0 2.4 3 0 0 3 3 3 0 AAA domain T2SSE PF00437.20 CRK22610.1 - 0.085 11.9 0.0 0.19 10.7 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein COX7C PF02935.16 CRK22611.1 - 3.6e-21 75.2 5.5 4.9e-21 74.8 5.5 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc PPR PF01535.20 CRK22612.1 - 5.7e-20 70.1 3.4 9.5e-06 25.5 0.0 6.2 6 0 0 6 6 6 4 PPR repeat PPR_2 PF13041.6 CRK22612.1 - 5.4e-19 68.1 0.2 1.3e-05 25.3 0.0 5.5 3 1 3 6 6 6 4 PPR repeat family PPR_3 PF13812.6 CRK22612.1 - 3.7e-13 49.3 0.0 0.00065 19.7 0.0 4.5 4 0 0 4 4 4 3 Pentatricopeptide repeat domain PPR_1 PF12854.7 CRK22612.1 - 5.6e-13 48.3 0.2 0.0014 18.3 0.1 4.1 4 0 0 4 4 4 3 PPR repeat PPR_long PF17177.4 CRK22612.1 - 2.9e-05 23.6 0.0 0.0064 15.9 0.0 2.9 1 1 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP MRP-S25 PF13741.6 CRK22613.1 - 2e-63 214.0 10.5 1.4e-59 201.4 4.1 2.1 1 1 1 2 2 2 2 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 CRK22613.1 - 0.00028 21.1 0.3 0.00091 19.5 0.3 1.9 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S23 Alg14 PF08660.11 CRK22615.1 - 8.4e-48 162.6 0.0 1.2e-47 162.0 0.0 1.2 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Ima1_N PF09779.9 CRK22616.1 - 3e-38 131.7 5.8 5.8e-38 130.8 5.8 1.5 1 0 0 1 1 1 1 Ima1 N-terminal domain Casein_kappa PF00997.18 CRK22616.1 - 0.021 14.9 0.5 0.059 13.5 0.5 1.8 1 0 0 1 1 1 0 Kappa casein DUF1451 PF07295.11 CRK22616.1 - 0.13 12.3 0.1 0.28 11.2 0.1 1.4 1 0 0 1 1 1 0 Zinc-ribbon containing domain DZR PF12773.7 CRK22616.1 - 0.19 11.8 3.1 8.7 6.5 0.2 2.5 2 0 0 2 2 2 0 Double zinc ribbon Y_phosphatase2 PF03162.13 CRK22617.1 - 5.2e-46 156.2 0.0 7.9e-46 155.6 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 CRK22617.1 - 1.1e-10 41.9 0.0 5.4e-10 39.6 0.0 2.0 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 CRK22617.1 - 0.0023 17.5 0.0 0.0033 17.0 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 CRK22617.1 - 0.0066 16.3 0.0 0.0096 15.7 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Aim19 PF10315.9 CRK22618.1 - 5.6e-05 23.4 0.2 8.5e-05 22.8 0.2 1.5 1 1 0 1 1 1 1 Altered inheritance of mitochondria protein 19 DUF1977 PF09320.11 CRK22619.1 - 6.6e-31 106.7 0.8 6.6e-31 106.7 0.8 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 CRK22619.1 - 2.6e-19 69.1 0.1 5.4e-19 68.1 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain Peptidase_M28 PF04389.17 CRK22620.1 - 2.3e-35 122.1 0.3 4.1e-35 121.3 0.3 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 CRK22620.1 - 5.1e-08 32.9 0.0 9.9e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 MINDY_DUB PF04424.13 CRK22621.1 - 4.2e-24 84.8 0.0 6.6e-24 84.2 0.0 1.3 1 0 0 1 1 1 1 MINDY deubiquitinase Steroid_dh PF02544.16 CRK22622.1 - 3.9e-19 69.1 1.4 7.4e-18 65.0 1.4 2.2 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 CRK22622.1 - 0.00024 20.7 0.2 0.00045 19.8 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) C6 PF01681.17 CRK22623.1 - 0.02 15.4 6.4 0.055 14.0 6.4 1.8 1 0 0 1 1 1 0 C6 domain Cu-oxidase_2 PF07731.14 CRK22624.1 - 4.9e-29 100.8 2.9 6.4e-27 94.0 2.6 2.5 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 CRK22624.1 - 3e-15 56.3 0.6 1.4e-14 54.1 0.1 2.3 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 CRK22624.1 - 0.0024 18.0 0.0 0.017 15.2 0.0 2.3 2 0 0 2 2 2 1 Multicopper oxidase DAO PF01266.24 CRK22625.1 - 1.2e-53 182.9 0.1 1.7e-53 182.5 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase MIP PF00230.20 CRK22625.1 - 3.8e-44 151.1 1.5 7.1e-44 150.2 1.5 1.3 1 0 0 1 1 1 1 Major intrinsic protein DAO_C PF16901.5 CRK22625.1 - 2.5e-41 140.5 0.0 4.5e-41 139.7 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 CRK22625.1 - 7.9e-09 35.1 2.7 0.0005 19.3 1.0 2.3 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 CRK22625.1 - 2.8e-06 27.0 0.8 0.00045 19.7 0.2 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CRK22625.1 - 0.00087 18.6 0.2 0.0022 17.3 0.2 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CRK22625.1 - 0.0026 18.0 0.1 0.026 14.8 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 CRK22625.1 - 0.025 13.7 0.7 0.22 10.6 0.2 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox PF00070.27 CRK22625.1 - 0.038 14.5 0.8 1.1 9.8 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 CRK22625.1 - 0.054 13.4 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 CRK22625.1 - 0.061 12.0 0.1 0.11 11.2 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 CRK22625.1 - 0.076 12.3 0.0 0.2 10.9 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FGGY_C PF02782.16 CRK22626.1 - 1.4e-70 237.1 1.9 2e-70 236.6 1.2 1.6 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 CRK22626.1 - 4.8e-66 222.8 0.0 6.3e-66 222.4 0.0 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Fungal_trans PF04082.18 CRK22627.1 - 2.6e-17 62.7 0.1 4.9e-17 61.8 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK22627.1 - 6.6e-08 32.6 9.5 1.5e-07 31.4 9.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MIP PF00230.20 CRK22628.1 - 1.1e-19 71.1 0.1 1.3e-19 70.8 0.1 1.1 1 0 0 1 1 1 1 Major intrinsic protein FGGY_N PF00370.21 CRK22629.1 - 4.3e-66 223.0 0.0 5.6e-66 222.6 0.0 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 CRK22629.1 - 1.4e-62 211.0 3.0 1.7e-62 210.7 2.0 1.6 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Fungal_trans PF04082.18 CRK22630.1 - 3.8e-17 62.2 0.1 7e-17 61.3 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK22630.1 - 3.1e-08 33.6 10.2 6.6e-08 32.6 10.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 CRK22631.1 - 0.14 12.2 0.1 0.35 10.9 0.0 1.7 2 0 0 2 2 2 0 PAS fold TIMELESS_C PF05029.13 CRK22631.1 - 0.14 11.3 4.0 0.23 10.6 4.0 1.2 1 0 0 1 1 1 0 Timeless protein C terminal region SPO22 PF08631.10 CRK22633.1 - 1.4e-46 159.3 0.3 1.3e-45 156.0 0.2 2.7 1 1 1 2 2 2 1 Meiosis protein SPO22/ZIP4 like Peptidase_C2 PF00648.21 CRK22634.1 - 1.6e-55 188.2 0.5 3.1e-40 138.0 0.1 2.3 1 1 1 2 2 2 2 Calpain family cysteine protease DUF1179 PF06678.11 CRK22634.1 - 1.2 9.1 5.7 3.9 7.5 5.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1179) Phage_min_cap2 PF06152.11 CRK22634.1 - 1.3 7.9 11.7 2.2 7.1 11.7 1.3 1 0 0 1 1 1 0 Phage minor capsid protein 2 Herpes_capsid PF06112.11 CRK22634.1 - 8.1 6.5 12.3 21 5.2 12.3 1.6 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Ufd2P_core PF10408.9 CRK22635.1 - 5.6e-211 702.4 4.7 5.6e-211 702.4 4.7 1.9 2 0 0 2 2 2 1 Ubiquitin elongating factor core U-box PF04564.15 CRK22635.1 - 2e-25 88.7 9.9 3.4e-23 81.6 0.9 3.5 4 0 0 4 4 3 2 U-box domain zf-TRAF PF02176.18 CRK22635.1 - 1.9e-13 50.9 23.2 9.7e-05 23.0 8.8 3.7 2 1 1 3 3 3 3 TRAF-type zinc finger zf-RING_UBOX PF13445.6 CRK22635.1 - 1.9e-07 30.9 12.1 4.3e-05 23.4 12.9 2.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CRK22635.1 - 7.7e-06 25.7 12.4 7.7e-06 25.7 12.4 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CRK22635.1 - 8.4e-06 25.9 9.3 9.3e-05 22.5 10.4 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 CRK22635.1 - 1.6e-05 24.7 12.4 1.6e-05 24.7 12.4 2.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CRK22635.1 - 5.2e-05 23.5 10.2 5.2e-05 23.5 10.2 3.6 2 1 2 4 4 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CRK22635.1 - 9e-05 22.3 7.8 9e-05 22.3 7.8 2.9 3 1 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CRK22635.1 - 0.00042 20.2 10.5 0.00042 20.2 10.5 2.5 2 1 0 2 2 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 CRK22635.1 - 0.0044 17.3 7.1 0.019 15.2 7.1 2.1 1 0 0 1 1 1 1 RING-H2 zinc finger domain Sina PF03145.16 CRK22635.1 - 0.019 14.9 10.8 0.058 13.3 1.2 2.5 2 0 0 2 2 2 0 Seven in absentia protein family zf-Nse PF11789.8 CRK22635.1 - 0.07 13.0 16.2 0.013 15.3 6.6 3.3 3 0 0 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit DUF4407 PF14362.6 CRK22635.1 - 0.095 12.0 1.4 0.22 10.8 1.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-ANAPC11 PF12861.7 CRK22635.1 - 0.14 12.2 5.1 0.31 11.1 5.1 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF641 PF04859.12 CRK22635.1 - 0.18 12.2 1.6 0.43 10.9 0.7 2.1 2 0 0 2 2 1 0 Plant protein of unknown function (DUF641) FAD_SOX PF18371.1 CRK22635.1 - 0.18 12.2 0.1 0.94 9.9 0.0 2.2 2 0 0 2 2 1 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase KLRAQ PF10205.9 CRK22635.1 - 0.3 11.3 5.2 1.4 9.2 1.0 2.7 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein Prok-RING_4 PF14447.6 CRK22635.1 - 0.49 10.3 11.0 7 6.6 11.4 2.6 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 LXG PF04740.12 CRK22635.1 - 1.2 8.8 4.0 1.5 8.5 0.1 2.7 2 1 0 3 3 3 0 LXG domain of WXG superfamily DivIC PF04977.15 CRK22635.1 - 2.3 8.1 4.4 32 4.4 4.7 2.5 2 0 0 2 2 2 0 Septum formation initiator zf-TRAF_2 PF15965.5 CRK22635.1 - 2.4 8.7 29.3 2.5 8.6 11.8 2.8 1 1 0 2 2 2 0 TRAF-like zinc-finger SOG2 PF10428.9 CRK22635.1 - 4.2 6.5 10.8 7.2 5.7 10.8 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Gelsolin PF00626.22 CRK22637.1 - 2.8e-35 120.1 0.1 6.1e-14 51.7 0.0 3.2 3 0 0 3 3 3 3 Gelsolin repeat PAS PF00989.25 CRK22638.1 - 0.44 10.6 0.0 0.44 10.6 0.0 2.5 3 0 0 3 3 3 0 PAS fold Pex14_N PF04695.13 CRK22638.1 - 0.6 10.8 25.4 0.38 11.4 12.6 3.2 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Spt20 PF12090.8 CRK22638.1 - 2.1 7.9 31.3 11 5.6 25.8 2.5 2 0 0 2 2 2 0 Spt20 family RR_TM4-6 PF06459.12 CRK22638.1 - 2.4 7.9 8.4 5.8 6.7 3.3 2.4 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 SPO22 PF08631.10 CRK22639.1 - 1e-49 169.5 3.6 3.2e-48 164.6 0.1 3.0 2 1 0 2 2 2 2 Meiosis protein SPO22/ZIP4 like TPR_12 PF13424.6 CRK22639.1 - 0.17 12.2 4.9 1.4 9.2 0.7 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Peptidase_C2 PF00648.21 CRK22640.1 - 3.1e-63 213.6 1.9 7e-62 209.1 1.9 2.2 1 1 0 1 1 1 1 Calpain family cysteine protease Ufd2P_core PF10408.9 CRK22641.1 - 3.6e-211 703.1 4.8 4.6e-211 702.7 4.8 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 CRK22641.1 - 2.2e-23 82.2 0.9 2.2e-23 82.2 0.9 2.5 2 0 0 2 2 2 1 U-box domain FAD_SOX PF18371.1 CRK22641.1 - 0.16 12.4 0.1 0.61 10.5 0.0 2.0 2 0 0 2 2 2 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase Fungal_trans PF04082.18 CRK22642.1 - 4.1e-22 78.5 0.1 6.7e-22 77.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK22642.1 - 2.8e-07 30.6 13.7 5.2e-07 29.7 13.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tmemb_cc2 PF10267.9 CRK22642.1 - 0.0049 16.1 0.0 0.007 15.6 0.0 1.1 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein Spc24 PF08286.11 CRK22642.1 - 0.16 12.2 0.3 0.26 11.6 0.3 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 A_deaminase PF00962.22 CRK22643.1 - 2.7e-61 207.7 0.0 1.3e-50 172.6 0.0 2.1 2 0 0 2 2 2 2 Adenosine/AMP deaminase Chitin_bind_1 PF00187.19 CRK22644.1 - 6.5e-08 32.9 16.1 1.2e-07 32.1 16.1 1.4 1 0 0 1 1 1 1 Chitin recognition protein A_deaminase PF00962.22 CRK22645.1 - 2.5e-44 151.9 0.0 3e-44 151.7 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Polysacc_deac_1 PF01522.21 CRK22646.1 - 6.3e-52 174.7 0.0 9.6e-31 106.3 0.0 2.3 2 0 0 2 2 2 2 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 CRK22646.1 - 1.2e-08 34.5 0.0 0.0018 17.6 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase family 57 Chitin_bind_1 PF00187.19 CRK22646.1 - 5.6e-07 29.9 16.7 9.9e-07 29.1 16.7 1.3 1 0 0 1 1 1 1 Chitin recognition protein DUF3461 PF11944.8 CRK22646.1 - 0.0028 17.8 0.0 3.3 7.8 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3461) Polysacc_deac_1 PF01522.21 CRK22648.1 - 4.8e-18 65.2 0.1 1.1e-17 64.1 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide deacetylase Abhydrolase_3 PF07859.13 CRK22649.1 - 6.7e-62 209.1 0.0 3.6e-23 82.5 0.0 4.4 4 0 0 4 4 4 4 alpha/beta hydrolase fold Lipase_3 PF01764.25 CRK22649.1 - 0.0043 16.9 0.0 4.6 7.1 0.0 2.4 2 0 0 2 2 2 2 Lipase (class 3) Say1_Mug180 PF10340.9 CRK22649.1 - 0.042 12.7 0.0 5.3 5.8 0.0 2.2 2 0 0 2 2 2 0 Steryl acetyl hydrolase DUF2974 PF11187.8 CRK22649.1 - 0.14 11.7 0.1 37 3.8 0.0 3.1 2 2 2 4 4 4 0 Protein of unknown function (DUF2974) Toxin_13 PF07822.11 CRK22649.1 - 0.17 12.0 0.0 45 4.3 0.0 2.9 2 0 0 2 2 2 0 Neurotoxin B-IV-like protein DUF3886 PF13025.6 CRK22649.1 - 0.21 11.8 1.4 11 6.2 0.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3886) Paramyxo_ncap PF00973.19 CRK22649.1 - 0.31 9.9 1.4 8.4 5.2 0.1 2.4 2 0 0 2 2 2 0 Paramyxovirus nucleocapsid protein Aminotran_3 PF00202.21 CRK22650.1 - 6.6e-54 183.1 0.0 8e-54 182.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III ATG27 PF09451.10 CRK22651.1 - 4.1e-131 436.6 0.0 3.4e-97 325.4 0.0 2.0 2 0 0 2 2 2 2 Autophagy-related protein 27 RE_BstXI PF09552.10 CRK22651.1 - 0.039 13.2 0.4 2.9 7.0 0.1 2.1 1 1 1 2 2 2 0 BstXI restriction endonuclease DUF374 PF04028.13 CRK22651.1 - 0.2 11.3 1.3 12 5.5 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF374) TNFR_16_TM PF18422.1 CRK22651.1 - 0.32 11.0 2.7 13 5.8 0.2 2.3 2 0 0 2 2 2 0 Tumor necrosis factor receptor member 16 trans-membrane domain RPN2_C PF18004.1 CRK22651.1 - 2.8 7.8 5.0 4.9 7.1 5.0 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain ATG27 PF09451.10 CRK22652.1 - 3.3e-77 259.9 0.1 9.9e-77 258.3 0.0 1.8 2 0 0 2 2 2 1 Autophagy-related protein 27 Spt20 PF12090.8 CRK22652.1 - 2.3e-69 233.6 1.9 2.6e-50 171.2 0.1 8.9 7 2 1 8 8 8 2 Spt20 family TruB_C PF09142.11 CRK22652.1 - 0.5 10.2 3.9 1.1 9.1 3.9 1.5 1 0 0 1 1 1 0 tRNA Pseudouridine synthase II, C terminal TruB_C PF09142.11 CRK22653.1 - 0.071 12.9 3.9 0.17 11.7 3.9 1.6 1 0 0 1 1 1 0 tRNA Pseudouridine synthase II, C terminal Hexapep PF00132.24 CRK22654.1 - 5.6e-06 25.9 5.0 0.004 16.8 1.1 3.0 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 CRK22654.1 - 1e-05 26.0 0.1 2.8e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 MobA-like NTP transferase domain Fucokinase PF07959.12 CRK22654.1 - 0.00013 21.1 0.2 0.00023 20.2 0.2 1.4 1 0 0 1 1 1 1 L-fucokinase DUF4954 PF16314.5 CRK22654.1 - 0.00081 17.6 2.5 0.0011 17.3 1.7 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4954) NTP_transferase PF00483.23 CRK22654.1 - 0.0011 18.7 0.0 0.0025 17.4 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyl transferase zf-RAG1 PF10426.9 CRK22654.1 - 0.029 14.5 0.7 2.5 8.3 0.2 2.8 2 0 0 2 2 2 0 Recombination-activating protein 1 zinc-finger domain Hexapep_2 PF14602.6 CRK22654.1 - 5.6 6.8 9.1 14 5.5 3.7 3.3 1 1 1 2 2 2 0 Hexapeptide repeat of succinyl-transferase 2-Hacid_dh_C PF02826.19 CRK22655.1 - 2.6e-46 157.2 0.0 1e-31 109.7 0.0 2.1 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CRK22655.1 - 0.14 11.8 0.0 0.2 11.3 0.0 1.4 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 2-Hacid_dh_C PF02826.19 CRK22656.1 - 5.7e-46 156.1 0.0 9.2e-32 109.8 0.0 2.1 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain XdhC_C PF13478.6 CRK22656.1 - 0.061 13.8 0.0 0.34 11.4 0.0 2.3 2 1 0 2 2 2 0 XdhC Rossmann domain DUF3446 PF11928.8 CRK22657.1 - 4.2 7.8 13.8 9.1 6.7 13.8 1.6 1 1 0 1 1 1 0 Early growth response N-terminal domain Topoisom_bac PF01131.20 CRK22658.1 - 2.2e-74 250.9 0.0 3.7e-68 230.4 0.0 2.1 2 0 0 2 2 2 2 DNA topoisomerase Hydrolase_6 PF13344.6 CRK22658.1 - 5.1e-27 93.9 0.0 1.2e-26 92.7 0.0 1.7 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase FoP_duplication PF13865.6 CRK22658.1 - 6.5 7.4 14.7 15 6.2 14.7 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Stb3 PF10330.9 CRK22659.1 - 1.4e-37 127.6 0.0 2.3e-37 126.9 0.0 1.3 1 0 0 1 1 1 1 Putative Sin3 binding protein SF1-HH PF16275.5 CRK22659.1 - 0.0079 16.5 0.0 0.016 15.5 0.0 1.4 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain Stb3 PF10330.9 CRK22660.1 - 0.00083 19.3 0.1 0.0014 18.7 0.1 1.3 1 0 0 1 1 1 1 Putative Sin3 binding protein zf-C2H2 PF00096.26 CRK22662.1 - 1.5e-06 28.4 19.1 2.2e-05 24.7 3.7 3.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CRK22662.1 - 3.7e-05 23.9 7.4 8.4e-05 22.8 4.2 3.0 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 CRK22662.1 - 5.4e-05 23.7 2.5 5.4e-05 23.7 2.5 3.9 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CRK22662.1 - 0.00021 21.5 1.3 0.0008 19.6 1.1 2.2 2 0 0 2 2 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 CRK22662.1 - 0.00041 20.6 4.3 0.001 19.3 4.3 1.7 1 0 0 1 1 1 1 C2H2-type zinc ribbon Cu-oxidase_2 PF07731.14 CRK22662.1 - 0.0023 17.6 1.9 1.8 8.3 0.1 2.5 2 0 0 2 2 2 2 Multicopper oxidase UNC119_bdg PF15435.6 CRK22662.1 - 0.018 14.6 0.4 7.2 6.1 0.0 2.4 2 0 0 2 2 2 0 UNC119-binding protein C5orf30 homologue zf-met PF12874.7 CRK22662.1 - 0.078 13.4 1.8 0.17 12.3 0.8 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 CRK22662.1 - 0.087 12.8 6.6 0.037 14.0 2.3 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-TRAF PF02176.18 CRK22662.1 - 0.23 12.2 6.8 0.12 13.1 3.3 2.1 2 0 0 2 2 2 0 TRAF-type zinc finger zf-C2HC_2 PF13913.6 CRK22662.1 - 0.34 10.9 1.8 0.7 9.9 1.8 1.6 1 0 0 1 1 1 0 zinc-finger of a C2HC-type DUF2524 PF10732.9 CRK22662.1 - 0.56 10.6 3.8 21 5.5 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2524) zf-C2H2_aberr PF17017.5 CRK22662.1 - 0.77 9.9 4.3 2.1 8.5 4.3 1.7 1 1 0 1 1 1 0 Aberrant zinc-finger FOXP-CC PF16159.5 CRK22662.1 - 1.2 9.8 8.1 2.3 8.9 0.5 3.1 1 1 2 3 3 3 0 FOXP coiled-coil domain SWIRM-assoc_2 PF16496.5 CRK22662.1 - 1.3 7.8 8.2 7.1 5.4 0.1 3.3 3 0 0 3 3 3 0 SWIRM-associated domain at the N-terminal zf-C2HE PF16278.5 CRK22662.1 - 1.8 9.0 5.0 5.5 7.5 5.0 1.9 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger POTRA_3 PF17287.2 CRK22662.1 - 8.9 5.9 5.5 51 3.4 0.3 3.1 3 0 0 3 3 3 0 POTRA domain SET PF00856.28 CRK22664.1 - 6.7e-08 33.1 0.0 2.1e-07 31.5 0.0 1.9 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 CRK22664.1 - 0.015 15.4 6.9 0.015 15.4 6.9 2.4 2 0 0 2 2 2 0 MYND finger MFS_1 PF07690.16 CRK22666.1 - 9e-33 113.6 34.5 3.2e-22 79.0 26.2 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK22666.1 - 0.00017 20.6 22.1 0.0018 17.2 0.4 3.4 2 1 1 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.16 CRK22669.1 - 1.2e-47 162.6 42.0 2e-47 161.8 42.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK22669.1 - 3.3e-15 55.9 22.7 2.2e-14 53.2 6.9 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter C1_1 PF00130.22 CRK22670.1 - 1.3 9.0 9.0 2.3 8.2 9.0 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Uroplakin_II PF07353.12 CRK22673.1 - 0.14 11.6 0.2 0.25 10.8 0.2 1.3 1 0 0 1 1 1 0 Uroplakin II AMPK1_CBM PF16561.5 CRK22674.1 - 2.4e-08 34.1 0.0 4.3e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Iwr1 PF08574.10 CRK22675.1 - 8e-10 39.6 9.7 8e-10 39.6 9.7 2.9 2 1 0 2 2 2 1 Transcription factor Iwr1 AMPK1_CBM PF16561.5 CRK22676.1 - 6.2e-07 29.5 0.0 1.2e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase LRR_4 PF12799.7 CRK22676.1 - 2.8e-05 24.4 1.0 0.14 12.6 0.0 3.7 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CRK22676.1 - 0.00024 20.9 8.0 0.15 12.2 0.0 5.3 6 0 0 6 6 6 2 Leucine Rich repeat Iwr1 PF08574.10 CRK22677.1 - 9.3e-10 39.4 9.9 9.3e-10 39.4 9.9 2.9 2 1 0 2 2 2 1 Transcription factor Iwr1 F-box-like PF12937.7 CRK22678.1 - 4.1e-21 74.6 0.7 4.1e-09 36.2 0.0 3.5 3 0 0 3 3 3 2 F-box-like F-box PF00646.33 CRK22678.1 - 3.8e-13 49.0 1.8 1.9e-05 24.4 0.1 3.0 3 0 0 3 3 3 2 F-box domain LRR_6 PF13516.6 CRK22678.1 - 8.4e-08 31.7 7.6 0.17 12.0 0.0 7.0 9 0 0 9 9 9 3 Leucine Rich repeat LRR_4 PF12799.7 CRK22678.1 - 9.5e-05 22.7 5.6 0.15 12.5 0.0 5.3 3 1 2 5 5 5 2 Leucine Rich repeats (2 copies) PRANC PF09372.10 CRK22678.1 - 0.00066 19.9 0.0 2.2 8.6 0.0 2.5 2 0 0 2 2 2 2 PRANC domain Alpha-mann_mid PF09261.11 CRK22678.1 - 0.00085 19.4 0.0 2.2 8.5 0.0 2.9 2 0 0 2 2 2 2 Alpha mannosidase middle domain F-box_4 PF15966.5 CRK22678.1 - 0.0023 17.8 0.0 2 8.4 0.0 2.5 2 0 0 2 2 2 2 F-box Mo-nitro_C PF06967.11 CRK22678.1 - 0.018 15.0 0.1 13 5.8 0.0 2.9 3 0 0 3 3 3 0 Mo-dependent nitrogenase C-terminus DUF3319 PF11782.8 CRK22678.1 - 0.024 14.6 0.0 1.2 9.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3319) Pkinase PF00069.25 CRK22679.1 - 2.7e-53 181.0 0.0 3.9e-53 180.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK22679.1 - 1.2e-19 70.7 0.0 2e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase His_Phos_1 PF00300.22 CRK22679.1 - 9.8e-14 51.5 0.1 1.6e-06 28.0 0.0 2.3 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Kinase-like PF14531.6 CRK22679.1 - 5.7e-06 25.8 0.0 1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CRK22679.1 - 0.0001 21.4 0.0 0.00016 20.8 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CRK22679.1 - 0.00021 21.3 0.3 0.0043 17.0 0.1 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 CRK22679.1 - 0.0019 17.6 0.1 0.0035 16.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CRK22679.1 - 0.015 14.9 0.1 0.037 13.6 0.1 1.6 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 CRK22679.1 - 0.02 13.7 0.1 0.057 12.2 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase RabGAP-TBC PF00566.18 CRK22680.1 - 3.3e-24 85.7 0.1 1.2e-23 83.9 0.0 2.0 2 0 0 2 2 2 1 Rab-GTPase-TBC domain zinc_ribbon_16 PF17034.5 CRK22680.1 - 4.7e-16 59.1 2.1 1.2e-15 57.9 2.1 1.6 1 0 0 1 1 1 1 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 CRK22680.1 - 0.00075 19.1 2.9 0.0016 18.0 2.9 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Aminotran_1_2 PF00155.21 CRK22680.1 - 0.011 14.9 2.5 2.5 7.2 0.2 2.7 2 0 0 2 2 2 0 Aminotransferase class I and II KinB_sensor PF16767.5 CRK22680.1 - 0.053 14.0 3.3 8.4 6.9 0.2 2.8 2 0 0 2 2 2 0 Sensor domain of alginate biosynthesis sensor protein KinB DUF5616 PF18481.1 CRK22680.1 - 0.097 13.0 0.1 31 4.9 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5616) PHA_synth_III_E PF09712.10 CRK22680.1 - 0.2 10.7 5.1 3.1 6.8 0.0 3.2 3 0 0 3 3 3 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) DUF2642 PF10842.8 CRK22680.1 - 0.21 11.4 0.4 34 4.4 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2642) Viral_DNA_bp PF00747.17 CRK22680.1 - 0.23 8.6 0.8 7.4 3.6 0.1 2.0 2 0 0 2 2 2 0 ssDNA binding protein AcylCoA_dehyd_C PF12186.8 CRK22680.1 - 1.9 8.6 8.3 6.1 7.0 1.0 2.5 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase C terminal dsrm PF00035.26 CRK22683.1 - 0.001 19.7 0.0 1.4 9.7 0.0 2.5 2 0 0 2 2 2 2 Double-stranded RNA binding motif Dicer_dimer PF03368.14 CRK22683.1 - 0.12 12.5 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 Dicer dimerisation domain PTS_2-RNA PF01885.16 CRK22685.1 - 4.3e-65 219.2 0.0 5e-65 218.9 0.0 1.0 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family RapH_N PF18801.1 CRK22685.1 - 0.071 13.2 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 response regulator aspartate phosphatase H, N terminal WD40 PF00400.32 CRK22686.1 - 0.013 16.3 0.1 33 5.6 0.0 3.8 4 0 0 4 4 4 0 WD domain, G-beta repeat Efg1 PF10153.9 CRK22687.1 - 5.6e-35 120.1 7.5 7.9e-35 119.7 7.5 1.2 1 0 0 1 1 1 1 rRNA-processing protein Efg1 DUF1481 PF07356.12 CRK22687.1 - 0.055 13.2 1.2 0.077 12.8 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1481) DSPc PF00782.20 CRK22691.1 - 1.4e-23 83.2 0.1 1.3e-21 76.8 0.1 2.2 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CRK22691.1 - 0.012 15.2 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 CRK22691.1 - 0.059 13.7 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Rit1 DUSP-like domain RNase_T PF00929.24 CRK22705.1 - 2.7e-16 60.5 0.0 1.2e-15 58.4 0.0 1.9 1 1 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 CRK22705.1 - 0.014 15.1 0.0 0.052 13.3 0.0 1.8 1 1 0 1 1 1 0 3'-5' exonuclease CMAS PF02353.20 CRK22706.1 - 2.1e-30 106.0 0.1 5.1e-30 104.7 0.1 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 CRK22706.1 - 0.026 15.2 0.0 0.043 14.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 CRK22706.1 - 0.044 13.6 0.0 0.063 13.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 CRK22706.1 - 0.058 14.1 0.0 0.11 13.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.12 CRK22706.1 - 0.19 11.5 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Pkinase PF00069.25 CRK22708.1 - 3.4e-18 66.0 0.0 2.3e-08 33.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CRK22708.1 - 4.2e-06 26.2 0.0 0.038 13.3 0.0 2.6 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CRK22708.1 - 0.00049 19.5 0.0 0.022 14.1 0.0 2.3 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 CRK22708.1 - 0.031 14.2 0.1 0.073 13.0 0.1 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Glyoxalase_3 PF13468.6 CRK22709.1 - 1.8e-21 77.0 0.1 2.7e-21 76.5 0.1 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain DUF1659 PF07872.11 CRK22709.1 - 0.15 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1659) MOZ_SAS PF01853.18 CRK22710.1 - 6.8e-80 266.9 0.0 9.8e-80 266.4 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 CRK22710.1 - 9.2e-21 73.2 0.5 1.6e-20 72.4 0.5 1.4 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 CRK22710.1 - 3e-17 62.3 0.1 1e-16 60.5 0.0 2.0 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 CRK22710.1 - 0.00029 21.2 0.0 0.00061 20.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CRK22710.1 - 0.025 14.8 0.0 0.055 13.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family NPR1_interact PF15699.5 CRK22710.1 - 3.6 8.3 8.2 9.4 6.9 7.1 2.1 1 1 1 2 2 2 0 NPR1 interacting RNase_T PF00929.24 CRK22711.1 - 7.2e-15 55.9 0.0 3e-14 53.9 0.0 1.9 1 1 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 CRK22711.1 - 0.1 12.3 0.0 0.35 10.6 0.0 1.9 1 1 0 1 1 1 0 3'-5' exonuclease CMAS PF02353.20 CRK22712.1 - 1.1e-69 234.8 0.0 2e-69 233.9 0.0 1.3 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 CRK22712.1 - 2e-11 44.4 0.0 4.2e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CRK22712.1 - 5e-11 43.1 0.0 9.4e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CRK22712.1 - 1.1e-07 31.8 0.0 1.8e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK22712.1 - 2.4e-07 30.7 0.0 4.1e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK22712.1 - 0.00039 21.1 0.0 0.00079 20.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 CRK22712.1 - 0.00078 19.3 0.0 0.0013 18.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF938 PF06080.12 CRK22712.1 - 0.051 13.3 0.0 0.4 10.4 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF938) RNase_H2_suC PF08615.11 CRK22713.1 - 8.3e-27 94.1 0.0 1.1e-26 93.8 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) MCM PF00493.23 CRK22714.1 - 1.1e-102 341.9 1.0 1.9e-102 341.1 1.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CRK22714.1 - 2.2e-38 131.0 0.2 4.3e-38 130.0 0.2 1.5 1 0 0 1 1 1 1 MCM OB domain MCM6_C PF18263.1 CRK22714.1 - 4.6e-30 104.0 0.0 1.1e-29 102.8 0.0 1.7 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_lid PF17855.1 CRK22714.1 - 1e-23 83.6 1.2 2.5e-23 82.3 0.6 2.1 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 CRK22714.1 - 1.9e-22 79.8 0.0 9.2e-22 77.6 0.0 2.3 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 CRK22714.1 - 1.8e-07 30.7 0.0 6.4e-07 29.0 0.0 1.9 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 CRK22714.1 - 0.00053 19.7 0.0 0.0012 18.5 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 CRK22714.1 - 0.0012 18.7 0.0 0.0031 17.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CRK22714.1 - 0.032 14.2 0.0 0.083 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) CCDC53 PF10152.9 CRK22714.1 - 0.29 11.6 1.4 6.1 7.2 0.1 2.7 3 0 0 3 3 3 0 Subunit CCDC53 of WASH complex F1F0-ATPsyn_F PF10791.9 CRK22716.1 - 1.7e-42 143.8 0.4 2e-42 143.6 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.9 CRK22716.1 - 0.00052 20.3 0.0 0.00069 19.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f ETC_C1_NDUFA4 PF04800.12 CRK22717.1 - 1.6e-36 124.4 1.8 2.6e-36 123.8 1.8 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region Copper-bind PF00127.20 CRK22717.1 - 0.066 13.7 0.0 0.13 12.7 0.0 1.4 1 1 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family CLTH PF10607.9 CRK22718.1 - 4.3e-26 91.6 0.1 6.1e-26 91.1 0.1 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 CRK22718.1 - 4e-09 36.1 0.0 9.4e-09 34.9 0.0 1.7 1 0 0 1 1 1 1 LisH PRK PF00485.18 CRK22719.1 - 1.6e-67 227.1 0.0 3.6e-41 141.1 0.1 2.2 1 1 1 2 2 2 2 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.6 CRK22719.1 - 5.4e-41 140.3 0.0 8e-41 139.8 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase CPT PF07931.12 CRK22719.1 - 3.4e-06 27.0 0.0 1.3e-05 25.1 0.0 1.9 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 CRK22719.1 - 5.4e-06 26.6 0.0 0.00015 22.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CRK22719.1 - 9.6e-06 26.2 0.1 0.00026 21.6 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 CRK22719.1 - 2.2e-05 24.9 1.1 1.1 9.7 0.1 3.4 3 0 0 3 3 3 2 AAA domain ABC_tran PF00005.27 CRK22719.1 - 0.00038 21.0 0.2 0.0024 18.4 0.1 2.1 2 0 0 2 2 2 1 ABC transporter AAA PF00004.29 CRK22719.1 - 0.0068 16.8 0.0 0.019 15.4 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Cytidylate_kin PF02224.18 CRK22719.1 - 0.0071 16.1 0.0 0.068 12.9 0.0 2.1 2 0 0 2 2 2 1 Cytidylate kinase Zeta_toxin PF06414.12 CRK22719.1 - 0.0092 15.3 0.0 0.017 14.4 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin NB-ARC PF00931.22 CRK22719.1 - 0.01 15.0 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_29 PF13555.6 CRK22719.1 - 0.016 14.9 0.5 0.05 13.3 0.1 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF87 PF01935.17 CRK22719.1 - 0.017 15.2 0.0 0.034 14.2 0.0 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain DUF2794 PF10984.8 CRK22719.1 - 0.03 14.4 0.0 5.6 7.2 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2794) dNK PF01712.19 CRK22719.1 - 0.031 14.1 0.0 1.7 8.4 0.0 2.4 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_16 PF13191.6 CRK22719.1 - 0.053 13.9 0.1 0.18 12.2 0.1 2.1 1 1 0 1 1 1 0 AAA ATPase domain DUF3109 PF11307.8 CRK22719.1 - 0.055 13.3 0.0 13 5.5 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3109) NACHT PF05729.12 CRK22719.1 - 0.067 13.1 0.1 0.17 11.8 0.1 1.6 1 0 0 1 1 1 0 NACHT domain APS_kinase PF01583.20 CRK22719.1 - 0.075 12.9 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase RNA_helicase PF00910.22 CRK22719.1 - 0.084 13.3 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Pribosyltran PF00156.27 CRK22719.1 - 0.11 12.1 0.0 0.34 10.4 0.0 1.7 2 0 0 2 2 2 0 Phosphoribosyl transferase domain RsgA_GTPase PF03193.16 CRK22719.1 - 0.13 12.2 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase MMR_HSR1 PF01926.23 CRK22719.1 - 0.16 12.1 0.1 0.37 10.9 0.1 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase NTPase_1 PF03266.15 CRK22719.1 - 0.17 11.8 0.0 0.4 10.6 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA_23 PF13476.6 CRK22719.1 - 0.23 12.0 0.7 0.53 10.7 0.7 1.5 1 1 0 1 1 1 0 AAA domain Pyr_redox_2 PF07992.14 CRK22720.1 - 4.5e-42 144.3 0.0 6.6e-42 143.7 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CRK22720.1 - 3.5e-12 46.7 0.0 6.9e-08 32.9 0.0 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.32 CRK22720.1 - 1.2e-06 27.7 0.2 2.7e-06 26.5 0.2 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 CRK22720.1 - 1.8e-05 24.3 0.4 5.1e-05 22.9 0.4 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 CRK22720.1 - 0.00011 21.5 0.7 0.00027 20.3 0.7 1.6 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 CRK22720.1 - 0.00022 21.6 0.3 0.00054 20.4 0.3 1.7 1 0 0 1 1 1 1 EF-hand domain pair Pyr_redox_3 PF13738.6 CRK22720.1 - 0.014 14.7 1.0 17 4.5 0.0 2.9 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Nop53 PF07767.11 CRK22721.1 - 4e-105 352.5 23.0 4.6e-105 352.3 23.0 1.0 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Kei1 PF08552.11 CRK22722.1 - 2.2e-57 194.0 2.3 3.8e-57 193.2 2.3 1.4 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 Ras PF00071.22 CRK22722.1 - 1.6e-41 141.6 0.2 2.6e-41 140.9 0.2 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CRK22722.1 - 1.3e-20 73.8 0.1 2.6e-20 72.8 0.1 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CRK22722.1 - 4.8e-11 42.4 0.5 7.1e-11 41.9 0.5 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CRK22722.1 - 5.7e-05 22.7 0.0 0.00015 21.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain TIR_2 PF13676.6 CRK22722.1 - 0.0068 17.0 0.3 0.43 11.2 0.1 2.3 2 0 0 2 2 2 1 TIR domain SPC12 PF06645.13 CRK22722.1 - 0.012 15.6 1.9 0.012 15.6 1.9 2.5 3 0 0 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) FlgH PF02107.16 CRK22722.1 - 0.052 13.2 0.2 0.078 12.6 0.2 1.2 1 0 0 1 1 1 0 Flagellar L-ring protein Nop53 PF07767.11 CRK22723.1 - 8.1e-104 348.2 22.1 9.3e-104 348.0 22.1 1.0 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) NIR_SIR PF01077.22 CRK22724.1 - 9.9e-56 187.6 0.2 9.5e-49 165.0 0.1 3.5 3 0 0 3 3 3 2 Nitrite and sulphite reductase 4Fe-4S domain Kei1 PF08552.11 CRK22724.1 - 1.1e-55 188.5 1.6 2.5e-55 187.3 1.6 1.7 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 Ras PF00071.22 CRK22724.1 - 2e-40 138.1 0.2 4.3e-40 137.0 0.2 1.4 1 0 0 1 1 1 1 Ras family Flavodoxin_1 PF00258.25 CRK22724.1 - 2.6e-31 108.7 0.0 7.2e-31 107.3 0.0 1.8 1 0 0 1 1 1 1 Flavodoxin NIR_SIR_ferr PF03460.17 CRK22724.1 - 1.5e-27 95.2 0.1 4.7e-14 52.0 0.1 2.5 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Roc PF08477.13 CRK22724.1 - 1.4e-19 70.5 0.1 3.2e-19 69.3 0.1 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase POR_N PF01855.19 CRK22724.1 - 5.5e-18 65.6 0.5 1.1e-07 31.8 0.0 2.6 2 0 0 2 2 2 2 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Arf PF00025.21 CRK22724.1 - 5.7e-10 38.9 0.5 1.2e-09 37.9 0.5 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CRK22724.1 - 0.0012 18.5 0.0 0.0023 17.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain SPC12 PF06645.13 CRK22724.1 - 0.04 14.0 1.3 0.19 11.9 1.3 2.1 1 0 0 1 1 1 0 Microsomal signal peptidase 12 kDa subunit (SPC12) TPR_12 PF13424.6 CRK22724.1 - 0.077 13.3 1.6 15 6.0 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Clr5 PF14420.6 CRK22727.1 - 1e-25 89.7 1.3 2.2e-25 88.6 1.3 1.7 1 0 0 1 1 1 1 Clr5 domain Glyco_transf_4 PF13439.6 CRK22727.1 - 0.13 12.3 0.3 0.99 9.4 0.0 2.5 2 1 1 3 3 3 0 Glycosyltransferase Family 4 MFS_1 PF07690.16 CRK22728.1 - 4.2e-21 75.3 28.6 5.9e-21 74.8 28.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily His_Phos_1 PF00300.22 CRK22728.1 - 1.7e-12 47.5 0.0 2.2e-09 37.3 0.0 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) DUF4149 PF13664.6 CRK22728.1 - 1.1 9.6 11.3 0.23 11.8 2.6 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) Acetyltransf_1 PF00583.25 CRK22732.1 - 1.5e-08 34.9 0.1 2.1e-08 34.4 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CRK22732.1 - 1.2e-07 31.7 0.3 2.6e-07 30.6 0.2 1.7 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CRK22732.1 - 5.5e-05 23.5 0.5 8.1e-05 23.0 0.1 1.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CRK22732.1 - 0.043 13.8 0.0 0.069 13.1 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein GNAT_acetyltr_2 PF13718.6 CRK22732.1 - 0.12 11.7 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase 2 CDC45 PF02724.14 CRK22733.1 - 4e-38 131.2 0.0 4.4e-38 131.0 0.0 1.0 1 0 0 1 1 1 1 CDC45-like protein Diphthamide_syn PF01866.17 CRK22736.1 - 7.2e-49 166.9 0.1 8.6e-49 166.6 0.1 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein MFS_1 PF07690.16 CRK22740.1 - 0.0072 15.3 12.7 0.0084 15.1 12.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Egh16-like PF11327.8 CRK22776.1 - 3.6e-53 180.7 10.0 4.4e-53 180.4 10.0 1.1 1 0 0 1 1 1 1 Egh16-like virulence factor p450 PF00067.22 CRK22777.1 - 2.7e-42 145.1 0.0 3.8e-42 144.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MBOAT_2 PF13813.6 CRK22778.1 - 3.8e-17 62.3 1.4 9.8e-17 61.0 1.4 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family DUF962 PF06127.11 CRK22778.1 - 5.8 7.1 8.1 15 5.8 1.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF962) CotJB PF12652.7 CRK22779.1 - 0.03 14.6 0.1 0.035 14.3 0.1 1.1 1 0 0 1 1 1 0 CotJB protein HSF_DNA-bind PF00447.17 CRK22781.1 - 6.7e-19 68.3 0.1 1.3e-18 67.3 0.1 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding PyocinActivator PF11112.8 CRK22781.1 - 0.14 12.3 0.2 7.5 6.8 0.0 2.6 3 0 0 3 3 3 0 Pyocin activator protein PrtN DUF1524 PF07510.11 CRK22784.1 - 3.1e-07 30.3 0.0 3.8e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) HNH_4 PF13395.6 CRK22784.1 - 0.044 13.7 0.4 0.62 10.0 0.4 2.3 1 1 0 1 1 1 0 HNH endonuclease Sugar_tr PF00083.24 CRK22785.1 - 3e-74 250.5 18.7 3.4e-74 250.3 18.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK22785.1 - 1.4e-10 40.7 23.0 1.4e-10 40.7 23.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sulfatase PF00884.23 CRK22786.1 - 2.9e-74 250.2 0.0 3.5e-74 250.0 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.6 CRK22786.1 - 0.00029 21.5 0.0 0.0054 17.5 0.0 2.2 1 1 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF4976 PF16347.5 CRK22786.1 - 0.014 15.6 0.0 0.029 14.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4976) DUF229 PF02995.17 CRK22786.1 - 0.064 11.9 0.0 0.096 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) TetR_C_12 PF16914.5 CRK22787.1 - 0.1 12.7 0.2 0.27 11.4 0.2 1.6 1 0 0 1 1 1 0 Bacterial transcriptional repressor C-terminal Zn-ribbon_8 PF09723.10 CRK22788.1 - 2.3 8.4 4.0 1.4 9.1 0.4 2.2 2 0 0 2 2 2 0 Zinc ribbon domain Methyltransf_23 PF13489.6 CRK22789.1 - 2.1e-17 63.4 0.0 3.4e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK22789.1 - 3.5e-14 53.3 0.0 7.9e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CRK22789.1 - 7.1e-12 45.8 0.0 1.5e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK22789.1 - 1.4e-09 38.6 0.0 2.6e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK22789.1 - 2.6e-08 33.8 0.0 6e-07 29.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CRK22789.1 - 0.00033 20.3 0.0 0.00052 19.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.9 CRK22789.1 - 0.00074 19.3 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 CRK22789.1 - 0.0013 18.2 0.0 0.002 17.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 CRK22789.1 - 0.006 16.0 0.0 2.8 7.2 0.0 2.2 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family DUF938 PF06080.12 CRK22789.1 - 0.0073 16.1 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) GidB PF02527.15 CRK22789.1 - 0.033 13.5 0.0 0.054 12.8 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_2 PF00891.18 CRK22789.1 - 0.082 12.2 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain FtsJ PF01728.19 CRK22789.1 - 0.084 13.0 0.0 0.31 11.1 0.0 1.8 2 0 0 2 2 2 0 FtsJ-like methyltransferase PCMT PF01135.19 CRK22789.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GSDH PF07995.11 CRK22790.1 - 0.018 14.4 0.8 0.84 8.9 0.3 3.3 2 1 0 3 3 3 0 Glucose / Sorbosone dehydrogenase NHL PF01436.21 CRK22790.1 - 0.037 14.1 0.1 4.3 7.6 0.1 3.4 2 1 0 2 2 2 0 NHL repeat DUF4448 PF14610.6 CRK22791.1 - 1.5e-30 106.4 0.0 2.3e-30 105.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) CENP-B_dimeris PF09026.10 CRK22791.1 - 3.9e-05 24.0 2.7 7.7e-05 23.0 2.7 1.5 1 0 0 1 1 1 1 Centromere protein B dimerisation domain TMEM154 PF15102.6 CRK22791.1 - 0.042 13.8 0.0 0.11 12.4 0.0 1.7 1 1 0 1 1 1 0 TMEM154 protein family Consortin_C PF15281.6 CRK22791.1 - 0.095 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Consortin C-terminus DUF3377 PF11857.8 CRK22791.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) NOA36 PF06524.12 CRK22791.1 - 0.12 11.7 7.6 0.2 11.0 7.6 1.3 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.11 CRK22791.1 - 0.18 11.8 1.5 0.36 10.9 1.5 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal PBP1_TM PF14812.6 CRK22791.1 - 0.23 11.8 7.9 0.097 13.1 5.0 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4229 PF14012.6 CRK22791.1 - 0.24 11.5 8.2 1.2 9.2 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) Sec66 PF09802.9 CRK22791.1 - 0.26 10.9 0.0 0.35 10.4 0.0 1.2 1 0 0 1 1 1 0 Preprotein translocase subunit Sec66 Osteopontin PF00865.18 CRK22791.1 - 0.26 10.7 10.6 0.5 9.8 10.6 1.4 1 0 0 1 1 1 0 Osteopontin DNA_pol_phi PF04931.13 CRK22791.1 - 0.41 8.7 6.2 0.57 8.2 6.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi Cwf_Cwc_15 PF04889.12 CRK22791.1 - 0.85 9.3 11.2 1.5 8.5 11.2 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein AA_permease_2 PF13520.6 CRK22793.1 - 1.6e-47 162.3 50.5 2e-47 162.0 50.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CRK22793.1 - 2.3e-32 112.2 45.5 3e-32 111.9 45.5 1.0 1 0 0 1 1 1 1 Amino acid permease GAPT PF11770.8 CRK22793.1 - 0.042 13.7 0.5 0.095 12.6 0.5 1.6 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) CTV_P6 PF06706.11 CRK22793.1 - 0.16 11.7 2.4 1.3 8.8 0.1 3.2 2 0 0 2 2 2 0 Citrus tristeza virus 6-kDa protein LUC7 PF03194.15 CRK22794.1 - 1.4e-23 83.8 0.0 1.7e-23 83.6 0.0 1.0 1 0 0 1 1 1 1 LUC7 N_terminus Caprin-1_C PF12287.8 CRK22794.1 - 1.8 8.6 5.5 2.4 8.2 5.5 1.2 1 0 0 1 1 1 0 Cytoplasmic activation/proliferation-associated protein-1 C term Thiolase_N PF00108.23 CRK22795.1 - 5.4e-54 183.3 0.8 9.6e-54 182.5 0.8 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CRK22795.1 - 3e-46 156.0 1.7 3.7e-46 155.8 0.5 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain IFRD PF05004.13 CRK22796.1 - 6.9e-21 74.6 0.2 8.7e-21 74.3 0.2 1.0 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) UTP15_C PF09384.10 CRK22798.1 - 1e-34 119.3 0.0 1.2e-34 119.1 0.0 1.0 1 0 0 1 1 1 1 UTP15 C terminal Fasciclin PF02469.22 CRK22824.1 - 1.2e-26 93.4 0.0 1.9e-20 73.4 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain GDC-P PF02347.16 CRK22826.1 - 1.7e-169 564.2 0.0 1e-157 525.4 0.0 2.3 2 0 0 2 2 2 2 Glycine cleavage system P-protein RRM_1 PF00076.22 CRK22826.1 - 1.9e-15 56.4 0.0 3.7e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 CRK22826.1 - 3.8e-13 49.7 11.2 0.04 14.8 0.0 7.5 8 0 0 8 8 8 4 WD domain, G-beta repeat Beta_elim_lyase PF01212.21 CRK22826.1 - 1.2e-06 28.1 0.0 2.1e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 CRK22826.1 - 2.5e-06 26.7 0.0 0.0014 17.6 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-V ANAPC4_WD40 PF12894.7 CRK22826.1 - 0.00011 22.4 0.0 0.82 10.0 0.0 4.1 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Cys_Met_Meta_PP PF01053.20 CRK22826.1 - 0.00067 18.3 0.0 0.014 13.9 0.0 2.1 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme RRM_5 PF13893.6 CRK22826.1 - 0.0084 15.7 0.0 0.023 14.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DegT_DnrJ_EryC1 PF01041.17 CRK22826.1 - 0.022 14.1 0.0 0.038 13.3 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Tom5 PF10642.9 CRK22828.1 - 5.3e-23 80.8 0.5 5.8e-23 80.7 0.5 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase Nup54 PF13874.6 CRK22830.1 - 2.4e-37 128.2 0.2 2.4e-37 128.2 0.2 3.4 3 1 0 3 3 3 1 Nucleoporin complex subunit 54 Nup54_57_C PF18570.1 CRK22830.1 - 1.5e-15 56.5 7.4 2.9e-15 55.5 7.4 1.5 1 0 0 1 1 1 1 NUP57/Nup54 C-terminal domain DivIVA PF05103.13 CRK22830.1 - 0.017 15.2 0.5 0.017 15.2 0.5 2.6 3 1 0 3 3 3 0 DivIVA protein DUF948 PF06103.11 CRK22830.1 - 0.28 11.4 1.1 1.9 8.8 0.2 2.6 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Presenilin PF01080.17 CRK22830.1 - 2.2 7.0 7.1 3.3 6.4 7.1 1.2 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 CRK22830.1 - 2.3 6.8 11.4 0.33 9.6 7.7 1.5 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Lin-8 PF03353.15 CRK22830.1 - 5.7 6.4 18.9 1.3 8.5 14.8 1.8 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Nucleoporin_FG PF13634.6 CRK22830.1 - 6 7.8 40.4 2.3 9.1 36.5 2.0 1 1 1 2 2 2 0 Nucleoporin FG repeat region CHCH PF06747.13 CRK22832.1 - 5.3e-05 23.2 4.4 7.5e-05 22.8 4.4 1.2 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 CRK22832.1 - 0.0057 16.6 3.1 0.0078 16.2 3.1 1.2 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, DnaT PF17948.1 CRK22832.1 - 0.054 13.2 0.0 2.4 7.9 0.0 2.1 2 0 0 2 2 2 0 DnaT DNA-binding domain SBE2 PF17076.5 CRK22832.1 - 0.073 11.3 0.2 0.085 11.1 0.2 1.0 1 0 0 1 1 1 0 SBE2, cell-wall formation CAP PF00188.26 CRK22835.1 - 6.6e-14 52.8 2.3 9e-14 52.4 2.3 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family TonB_N PF16031.5 CRK22835.1 - 0.00081 19.9 30.4 0.0014 19.1 30.4 1.4 1 0 0 1 1 1 1 TonB polyproline region DUF2868 PF11067.8 CRK22835.1 - 0.16 11.4 2.8 0.25 10.8 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) PRCC PF10253.9 CRK22835.1 - 0.49 11.1 5.4 0.6 10.9 5.4 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting CCDC53 PF10152.9 CRK22835.1 - 2.3 8.6 5.3 3.4 8.1 5.3 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex CDC27 PF09507.10 CRK22836.1 - 7.4 5.8 47.1 0.2 11.0 34.0 2.0 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 PCI PF01399.27 CRK22837.1 - 1.2e-22 80.4 0.2 4.4e-22 78.6 0.1 2.1 2 0 0 2 2 2 1 PCI domain RPN5_C PF18098.1 CRK22837.1 - 5.2e-16 58.4 1.1 1.2e-15 57.3 1.1 1.7 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain AltA1 PF16541.5 CRK22837.1 - 6.5e-14 52.7 0.0 1.7e-13 51.4 0.0 1.6 1 0 0 1 1 1 1 Alternaria alternata allergen 1 FSH1 PF03959.13 CRK22839.1 - 3e-60 203.5 0.0 3.9e-60 203.1 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 CRK22839.1 - 2.7e-05 24.9 3.0 9.9e-05 23.0 3.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CRK22839.1 - 0.0012 18.1 0.2 0.11 11.8 0.0 2.5 2 1 1 3 3 3 2 Serine aminopeptidase, S33 PE-PPE PF08237.11 CRK22839.1 - 0.019 14.5 0.0 0.035 13.7 0.0 1.4 1 0 0 1 1 1 0 PE-PPE domain Abhydrolase_1 PF00561.20 CRK22839.1 - 0.029 14.0 0.1 1 8.9 0.1 2.3 1 1 1 2 2 2 0 alpha/beta hydrolase fold Esterase PF00756.20 CRK22839.1 - 0.17 11.5 0.6 3.1 7.4 0.3 2.1 2 0 0 2 2 2 0 Putative esterase NIPSNAP PF07978.13 CRK22840.1 - 1e-41 141.3 2.3 1.3e-30 105.6 0.2 2.5 2 0 0 2 2 2 2 NIPSNAP Rogdi_lz PF10259.9 CRK22841.1 - 9.1e-90 300.7 0.0 1.1e-89 300.5 0.0 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein Rpp20 PF12328.8 CRK22842.1 - 2.6e-29 101.9 0.4 3.7e-29 101.4 0.4 1.2 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 CRK22842.1 - 8.4e-13 47.9 0.0 1.6e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Alba SH3_9 PF14604.6 CRK22843.1 - 2.6e-10 40.0 2.4 4.3e-07 29.7 0.3 2.8 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.17 CRK22843.1 - 0.00027 20.5 0.5 0.00027 20.5 0.5 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 CRK22843.1 - 0.43 10.2 5.3 0.063 12.9 0.8 2.0 2 0 0 2 2 2 0 SH3 domain Lyase_1 PF00206.20 CRK22844.1 - 1.4e-109 366.3 0.0 2.2e-109 365.7 0.0 1.3 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 CRK22844.1 - 1.5e-21 76.6 0.1 3.3e-21 75.4 0.1 1.7 1 0 0 1 1 1 1 Fumarase C C-terminus Glyco_hydro_2_N PF02837.18 CRK22845.1 - 1.6e-13 50.9 0.1 4.1e-13 49.6 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 CRK22845.1 - 1.6e-08 35.2 0.0 2.9e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Zn_clus PF00172.18 CRK22845.1 - 3.4e-06 27.1 4.2 7.4e-06 26.0 4.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_2_C PF02836.17 CRK22845.1 - 1.8e-05 24.1 0.0 4.5e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain BetaGal_dom4_5 PF13364.6 CRK22845.1 - 0.00046 20.7 0.0 0.00097 19.7 0.0 1.5 1 0 0 1 1 1 1 Beta-galactosidase jelly roll domain Fungal_trans_2 PF11951.8 CRK22845.1 - 0.044 12.6 0.1 0.069 11.9 0.1 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain zf-C2H2_4 PF13894.6 CRK22847.1 - 0.0051 17.6 4.0 0.0051 17.6 4.0 4.5 5 0 0 5 5 5 1 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CRK22847.1 - 9.6 6.8 10.6 2.2 8.8 3.3 3.3 3 0 0 3 3 3 0 Zinc-finger double domain NAD_binding_10 PF13460.6 CRK22848.1 - 4.5e-11 43.0 0.0 9.7e-11 41.9 0.0 1.5 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 CRK22848.1 - 1.4e-10 41.2 0.1 1.8e-10 40.8 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 CRK22848.1 - 0.004 16.6 0.5 0.0064 16.0 0.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 CRK22848.1 - 0.023 14.2 0.1 0.26 10.7 0.1 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family KR PF08659.10 CRK22848.1 - 0.033 14.1 0.1 0.052 13.4 0.1 1.3 1 0 0 1 1 1 0 KR domain 3Beta_HSD PF01073.19 CRK22848.1 - 0.093 11.7 0.0 0.38 9.7 0.1 1.8 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_11 PF00457.17 CRK22849.1 - 2.6e-34 118.4 0.8 2.8e-34 118.3 0.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Glyco_hydro_88 PF07470.13 CRK22851.1 - 5.2e-37 127.7 3.2 6.2e-37 127.5 3.2 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 SURF1 PF02104.15 CRK22852.1 - 9.3e-28 97.6 0.0 1.3e-27 97.2 0.0 1.2 1 0 0 1 1 1 1 SURF1 family Apolipoprotein PF01442.18 CRK22852.1 - 0.047 13.6 1.2 0.086 12.7 1.2 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Lyase_1 PF00206.20 CRK22854.1 - 7.6e-30 104.4 0.0 8.4e-30 104.2 0.0 1.0 1 0 0 1 1 1 1 Lyase Imm40 PF15569.6 CRK22854.1 - 0.2 11.8 0.0 0.38 10.9 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 40 Mito_carr PF00153.27 CRK22857.1 - 7e-06 25.9 0.0 1.3e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial carrier protein 2OG-FeII_Oxy PF03171.20 CRK22859.1 - 0.00014 22.3 0.0 0.00017 22.0 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily IU_nuc_hydro PF01156.19 CRK22861.1 - 5e-37 128.1 0.7 6e-37 127.9 0.7 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Glyco_hydro_3_C PF01915.22 CRK22861.1 - 0.027 14.4 0.0 0.032 14.2 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain EF1G PF00647.19 CRK22873.1 - 5e-43 145.5 0.0 8.4e-43 144.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 CRK22873.1 - 2.4e-14 53.3 0.0 4.7e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CRK22873.1 - 7.7e-08 32.3 0.1 4.9e-07 29.7 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CRK22873.1 - 4.3e-05 23.6 0.0 9.8e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DEC-1_N PF04625.13 CRK22873.1 - 0.0089 15.1 4.6 0.013 14.6 4.6 1.2 1 0 0 1 1 1 1 DEC-1 protein, N-terminal region GST_C_6 PF17171.4 CRK22873.1 - 0.04 13.7 0.0 0.3 10.9 0.0 2.2 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain NIF PF03031.18 CRK22874.1 - 2.2e-17 63.2 0.0 3.9e-17 62.4 0.0 1.4 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase RRP36 PF06102.12 CRK22876.1 - 1.1e-55 188.1 30.9 1.1e-55 188.1 30.9 2.1 2 1 0 2 2 2 1 rRNA biogenesis protein RRP36 ABC1 PF03109.16 CRK22878.1 - 4.4e-32 110.7 0.0 8.8e-32 109.8 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Es2 PF09751.9 CRK22879.1 - 3e-121 406.2 10.5 3.5e-121 406.0 10.5 1.1 1 0 0 1 1 1 1 Nuclear protein Es2 PPP5 PF08321.12 CRK22881.1 - 9.1e-32 109.2 0.1 2.4e-31 107.9 0.0 1.8 2 0 0 2 2 2 1 PPP5 TPR repeat region Metallophos PF00149.28 CRK22881.1 - 2.9e-31 109.5 0.0 4.2e-31 109.1 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_1 PF00515.28 CRK22881.1 - 3.8e-18 64.5 0.8 2.4e-05 24.0 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CRK22881.1 - 3.1e-14 51.9 0.4 0.0005 20.0 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 CRK22881.1 - 1.3e-09 37.6 1.4 0.0081 15.8 0.2 3.5 2 1 1 3 3 3 3 TPR repeat TPR_8 PF13181.6 CRK22881.1 - 5.1e-08 32.5 0.2 0.0071 16.5 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 CRK22881.1 - 4.6e-05 23.5 0.0 0.00011 22.2 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 CRK22881.1 - 0.00017 21.8 4.9 0.6 10.6 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 CRK22881.1 - 0.0025 18.4 0.0 0.031 14.9 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 CRK22881.1 - 0.0041 17.4 0.0 2.4 8.5 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 CRK22881.1 - 0.018 15.5 0.0 11 6.6 0.0 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 CRK22881.1 - 0.063 14.1 0.0 2.5 9.1 0.0 3.2 1 1 2 3 3 3 0 Tetratricopeptide repeat EMP24_GP25L PF01105.24 CRK22886.1 - 2.9e-45 154.5 1.4 3.3e-45 154.3 1.4 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD PhoD PF09423.10 CRK22887.1 - 1.1e-43 149.6 0.1 2.4e-43 148.5 0.1 1.5 1 1 0 1 1 1 1 PhoD-like phosphatase TauD PF02668.16 CRK22889.1 - 1.2e-40 140.0 0.0 1.7e-40 139.5 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 CRK22889.1 - 2e-12 47.6 0.0 3.9e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF971) Cyclase PF04199.13 CRK22893.1 - 3.6e-13 49.9 0.0 5.2e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase Helicase_C PF00271.31 CRK22895.1 - 8.7e-12 45.4 0.1 7.4e-11 42.4 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HA2 PF04408.23 CRK22895.1 - 1.2e-09 38.4 0.0 1.2e-09 38.4 0.0 2.5 3 0 0 3 3 3 1 Helicase associated domain (HA2) DEAD PF00270.29 CRK22895.1 - 1.3e-09 38.1 0.1 2.9e-09 37.0 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 CRK22895.1 - 4.2e-07 30.2 0.0 1.1e-06 29.0 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_19 PF13245.6 CRK22895.1 - 5.2e-05 23.6 0.0 0.00011 22.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CRK22895.1 - 0.0002 21.6 0.0 0.00063 20.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 CRK22895.1 - 0.00029 20.0 0.1 0.0036 16.4 0.0 2.1 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.6 CRK22895.1 - 0.0012 18.5 0.0 0.0025 17.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 CRK22895.1 - 0.0095 16.5 5.0 0.15 12.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 CRK22895.1 - 0.033 13.6 0.1 0.083 12.3 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein ATPase PF06745.13 CRK22895.1 - 0.067 12.5 3.3 0.092 12.1 0.0 2.1 2 0 0 2 2 2 0 KaiC ResIII PF04851.15 CRK22895.1 - 0.084 12.9 1.4 1.1 9.2 0.0 2.7 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit DUF2075 PF09848.9 CRK22895.1 - 0.1 11.8 0.0 0.1 11.8 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) SesA PF17107.5 CRK22897.1 - 2.3e-09 37.5 0.1 6.1e-08 32.9 0.0 2.5 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA_23 PF13476.6 CRK22897.1 - 0.003 18.1 0.1 0.052 14.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 CRK22897.1 - 0.0061 16.7 0.6 0.49 10.5 0.0 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_16 PF13191.6 CRK22897.1 - 0.013 15.9 1.3 0.07 13.5 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 CRK22897.1 - 0.016 15.5 0.3 0.11 12.8 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 CRK22897.1 - 0.02 14.6 0.1 0.041 13.6 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.22 CRK22897.1 - 0.032 13.4 0.0 0.061 12.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.27 CRK22897.1 - 0.039 14.5 0.2 0.29 11.7 0.0 2.3 2 1 0 2 2 2 0 ABC transporter ATPase_2 PF01637.18 CRK22897.1 - 0.043 13.7 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea CENP-K PF11802.8 CRK22897.1 - 0.054 13.1 0.6 0.1 12.2 0.6 1.4 1 0 0 1 1 1 0 Centromere-associated protein K AAA_30 PF13604.6 CRK22897.1 - 0.058 13.1 0.1 0.44 10.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 CRK22897.1 - 0.068 13.1 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 NACHT domain RsgA_GTPase PF03193.16 CRK22897.1 - 0.082 12.8 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase Roc PF08477.13 CRK22897.1 - 0.09 13.0 0.1 0.43 10.8 0.0 2.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 CRK22897.1 - 0.11 12.1 0.0 0.4 10.3 0.0 2.0 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain GP57 PF17594.2 CRK22897.1 - 0.12 12.1 0.2 0.65 9.8 0.0 2.1 2 0 0 2 2 2 0 Phage Tail fiber assembly helper gene product 57 PI3K_1B_p101 PF10486.9 CRK22897.1 - 0.85 7.3 7.3 2.9 5.6 5.9 2.1 1 1 0 2 2 2 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit SDA1 PF05285.12 CRK22897.1 - 9.3 5.6 15.6 18 4.7 15.6 1.4 1 0 0 1 1 1 0 SDA1 DUF2264 PF10022.9 CRK22904.1 - 3.2e-37 128.5 0.0 3.8e-37 128.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) Aminotran_5 PF00266.19 CRK22906.1 - 9.4e-28 97.2 0.0 4.2e-17 62.1 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V VAPB_antitox PF02697.14 CRK22906.1 - 0.028 15.2 0.0 0.055 14.2 0.0 1.5 1 0 0 1 1 1 0 Putative antitoxin PheRS_DBD2 PF18554.1 CRK22906.1 - 0.15 12.1 0.4 2.2 8.3 0.1 2.7 2 0 0 2 2 2 0 PheRS DNA binding domain 2 adh_short PF00106.25 CRK22908.1 - 2.3e-18 66.4 0.0 3.8e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK22908.1 - 4.1e-16 59.2 0.0 6.3e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase SNRNP27 PF08648.12 CRK22910.1 - 1.4e-28 98.7 2.1 2.7e-28 97.8 2.1 1.5 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins Gti1_Pac2 PF09729.9 CRK22912.1 - 6.1e-08 33.0 0.2 0.013 15.6 0.0 2.3 2 0 0 2 2 2 2 Gti1/Pac2 family Longin PF13774.6 CRK22914.1 - 2.5e-21 75.5 0.1 3.6e-21 75.0 0.1 1.2 1 0 0 1 1 1 1 Regulated-SNARE-like domain ASXH PF13919.6 CRK22916.1 - 1.5e-35 122.2 0.1 1.5e-35 122.2 0.1 1.7 2 0 0 2 2 2 1 Asx homology domain CLPTM1 PF05602.12 CRK22917.1 - 1.1e-35 123.5 0.8 1.5e-35 123.1 0.8 1.2 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) DUF1772 PF08592.11 CRK22917.1 - 0.041 14.2 12.9 0.47 10.8 1.5 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) UCR_TM PF02921.14 CRK22917.1 - 1.7 9.2 3.8 5.3 7.6 0.1 3.1 2 1 1 3 3 3 0 Ubiquinol cytochrome reductase transmembrane region CbiM PF01891.16 CRK22917.1 - 1.8 8.3 6.1 0.27 11.1 2.1 1.6 2 0 0 2 2 2 0 Cobalt uptake substrate-specific transmembrane region CLPTM1 PF05602.12 CRK22918.1 - 1.1e-46 159.8 0.1 1.6e-46 159.2 0.1 1.2 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) Synaptobrevin PF00957.21 CRK22918.1 - 4.4e-14 52.0 0.2 1e-13 50.9 0.0 1.7 2 0 0 2 2 2 1 Synaptobrevin Longin PF13774.6 CRK22918.1 - 2.8e-05 24.1 0.1 7.5e-05 22.7 0.1 1.7 1 1 0 1 1 1 1 Regulated-SNARE-like domain DUF5435 PF17503.2 CRK22918.1 - 0.05 13.3 0.0 0.077 12.7 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5435) Ras PF00071.22 CRK22920.1 - 1.5e-40 138.5 0.1 1.6e-40 138.4 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CRK22920.1 - 7.4e-30 103.6 0.1 8e-30 103.5 0.1 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CRK22920.1 - 3.4e-08 33.1 0.1 3.6e-08 33.1 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CRK22920.1 - 7.8e-07 29.2 0.0 9.5e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CRK22920.1 - 0.0071 16.3 0.2 0.013 15.4 0.1 1.6 1 1 1 2 2 2 1 RsgA GTPase Gtr1_RagA PF04670.12 CRK22920.1 - 0.01 15.2 0.0 0.011 15.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 CRK22920.1 - 0.015 15.6 0.0 0.018 15.3 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_21 PF13304.6 CRK22920.1 - 0.038 13.8 0.0 0.038 13.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system GTP_EFTU PF00009.27 CRK22920.1 - 0.042 13.4 0.0 0.079 12.5 0.0 1.5 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 CRK22920.1 - 0.042 14.2 0.1 0.044 14.2 0.1 1.3 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 CRK22920.1 - 0.05 14.1 0.1 0.053 14.0 0.1 1.3 1 1 0 1 1 1 0 ABC transporter TniB PF05621.11 CRK22920.1 - 0.089 12.2 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein SRPRB PF09439.10 CRK22920.1 - 0.1 12.0 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MFS_1 PF07690.16 CRK22922.1 - 2.1e-08 33.5 14.8 2.6e-08 33.2 14.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily HTH_36 PF13730.6 CRK22923.1 - 0.14 12.2 0.2 0.27 11.2 0.0 1.5 2 0 0 2 2 2 0 Helix-turn-helix domain GST_N_3 PF13417.6 CRK22924.1 - 4.7e-13 49.3 0.0 7.2e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CRK22924.1 - 4.3e-12 46.1 0.0 5.8e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 CRK22924.1 - 1.2e-05 25.6 0.0 1.6e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 CRK22924.1 - 0.004 17.9 0.0 0.0055 17.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 CRK22924.1 - 0.0057 17.0 0.0 0.01 16.1 0.0 1.4 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein IPP-2 PF04979.14 CRK22925.1 - 5.3e-09 36.9 2.7 6.4e-09 36.6 2.7 1.1 1 0 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) VID27 PF08553.10 CRK22930.1 - 1.2e-56 192.3 0.0 1.3e-56 192.2 0.0 1.0 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain PI3K_1B_p101 PF10486.9 CRK22932.1 - 8 4.1 11.9 10 3.7 11.9 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Pyr_redox_2 PF07992.14 CRK22934.1 - 2.9e-17 62.9 0.0 3.7e-11 42.8 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CRK22934.1 - 2.4e-05 23.7 0.2 0.0002 20.6 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 CRK22934.1 - 0.00018 20.9 0.1 0.24 10.6 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CRK22934.1 - 0.00081 19.6 0.1 0.011 16.0 0.2 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 CRK22934.1 - 0.0034 16.1 0.2 0.011 14.5 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 CRK22934.1 - 0.0036 16.4 0.1 0.048 12.7 0.1 2.5 3 0 0 3 3 3 1 FAD binding domain NAD_binding_9 PF13454.6 CRK22934.1 - 0.0051 16.8 0.8 2.8 7.9 0.3 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding GIDA PF01134.22 CRK22934.1 - 0.0059 15.7 0.0 0.54 9.3 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A DAO PF01266.24 CRK22934.1 - 0.029 14.0 0.2 0.26 10.9 0.1 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 CRK22934.1 - 0.071 12.4 0.1 0.13 11.6 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 CRK22934.1 - 0.079 12.2 0.2 0.13 11.5 0.2 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.19 CRK22934.1 - 0.088 12.0 0.1 0.15 11.2 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 CRK22934.1 - 0.1 11.7 1.0 0.36 9.8 0.6 1.9 1 1 1 2 2 2 0 Lycopene cyclase protein BUD22 PF09073.10 CRK22937.1 - 0.48 9.7 9.4 0.81 9.0 9.4 1.3 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 CRK22937.1 - 4.7 6.5 15.1 7.9 5.8 15.1 1.2 1 0 0 1 1 1 0 SDA1 Ank_2 PF12796.7 CRK22938.1 - 2.1e-10 41.0 0.0 0.03 14.9 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CRK22938.1 - 1.7e-09 38.0 0.0 0.03 14.9 0.0 6.1 6 0 0 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CRK22938.1 - 3.8e-08 33.0 0.3 0.46 11.2 0.0 6.1 6 0 0 6 6 6 2 Ankyrin repeat Ank PF00023.30 CRK22938.1 - 6.7e-06 26.3 0.4 0.26 11.8 0.0 5.5 5 2 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.6 CRK22938.1 - 1.1e-05 25.6 0.0 1.7 9.0 0.0 5.1 4 0 0 4 4 4 1 Ankyrin repeats (many copies) MFS_1 PF07690.16 CRK22940.1 - 2.7e-19 69.3 45.8 2.5e-14 53.0 26.7 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily ABC_tran PF00005.27 CRK22942.1 - 8e-53 178.6 0.2 3e-29 102.3 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 CRK22942.1 - 2.9e-18 66.1 41.0 4.9e-10 39.0 12.9 2.5 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 CRK22942.1 - 1.8e-15 57.5 1.1 0.00014 21.8 0.0 4.3 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CRK22942.1 - 3.1e-12 46.4 0.2 6.3e-05 22.5 0.0 4.1 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CRK22942.1 - 2.2e-06 28.3 0.1 0.069 13.6 0.1 2.3 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 CRK22942.1 - 1.1e-05 25.4 0.0 0.0023 17.9 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 CRK22942.1 - 1.2e-05 25.0 0.4 0.26 11.1 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 CRK22942.1 - 0.00011 22.5 0.3 0.54 10.5 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_30 PF13604.6 CRK22942.1 - 0.00032 20.5 0.4 0.88 9.3 0.1 2.7 2 1 0 2 2 2 2 AAA domain NB-ARC PF00931.22 CRK22942.1 - 0.00039 19.7 1.4 2.6 7.2 0.3 3.7 3 1 0 3 3 3 1 NB-ARC domain AAA_16 PF13191.6 CRK22942.1 - 0.00048 20.6 0.0 0.085 13.2 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 CRK22942.1 - 0.001 18.8 0.1 4 7.1 0.0 4.0 4 0 0 4 4 4 1 IstB-like ATP binding protein SRP54 PF00448.22 CRK22942.1 - 0.0012 18.5 0.6 1.7 8.2 0.0 2.5 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 CRK22942.1 - 0.0032 16.8 0.1 1.9 7.7 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin MukB PF04310.12 CRK22942.1 - 0.0055 16.5 0.2 2.5 7.8 0.0 3.2 3 0 0 3 3 3 1 MukB N-terminal AAA_24 PF13479.6 CRK22942.1 - 0.006 16.3 0.0 2 8.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 CRK22942.1 - 0.01 15.8 0.0 6 6.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 CRK22942.1 - 0.012 14.6 0.2 0.17 10.9 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein SbcCD_C PF13558.6 CRK22942.1 - 0.015 15.5 0.2 14 6.0 0.0 3.9 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 CRK22942.1 - 0.022 14.5 0.1 7.8 6.1 0.1 2.6 3 0 0 3 3 3 0 AAA ATPase domain AAA_13 PF13166.6 CRK22942.1 - 0.027 13.1 0.0 5.3 5.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 CRK22942.1 - 0.031 13.7 0.6 3.3 7.1 0.1 3.0 2 1 0 3 3 3 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 CRK22942.1 - 0.036 14.1 0.2 0.69 9.9 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 CRK22942.1 - 0.041 14.3 2.2 14 6.1 0.4 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 CRK22942.1 - 0.074 13.3 0.1 1.4 9.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 CRK22942.1 - 0.077 12.6 0.0 14 5.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 CRK22942.1 - 0.093 12.6 0.0 19 5.1 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_18 PF13238.6 CRK22942.1 - 0.13 12.8 0.1 10 6.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 CRK22942.1 - 0.14 12.5 0.1 19 5.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 CRK22942.1 - 0.2 10.8 0.1 11 5.0 0.1 2.4 2 0 0 2 2 2 0 G-protein alpha subunit PduV-EutP PF10662.9 CRK22942.1 - 0.26 11.0 0.7 1.9 8.2 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Fungal_trans PF04082.18 CRK22946.1 - 1.4e-19 70.2 0.7 2.2e-19 69.5 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 CRK22948.1 - 2.8e-79 267.1 25.5 3.2e-79 266.9 25.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK22948.1 - 1.5e-16 60.3 39.4 1.3e-15 57.2 14.1 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Ilm1 PF10311.9 CRK22948.1 - 0.077 12.6 1.8 0.17 11.5 1.8 1.5 1 0 0 1 1 1 0 Increased loss of mitochondrial DNA protein 1 MFS_1_like PF12832.7 CRK22948.1 - 0.4 9.5 16.3 0.023 13.6 5.6 2.9 2 1 1 3 3 3 0 MFS_1 like family NPP1 PF05630.11 CRK22950.1 - 3.9e-66 222.9 0.0 4.5e-66 222.7 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Ferric_reduct PF01794.19 CRK22952.1 - 6.7e-19 68.2 14.8 6.7e-19 68.2 14.8 2.4 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 CRK22952.1 - 8e-05 22.8 3.7 0.026 14.6 0.0 2.6 2 1 1 3 3 3 2 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 CRK22952.1 - 8.8e-05 23.1 0.0 0.00022 21.9 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_8 PF08022.12 CRK22952.1 - 0.00042 20.4 0.1 0.0022 18.0 0.1 2.3 1 1 0 1 1 1 1 FAD-binding domain Ferritin_2 PF13668.6 CRK22956.1 - 3.5e-41 140.6 1.0 4.6e-41 140.2 1.0 1.1 1 0 0 1 1 1 1 Ferritin-like domain Iso_dh PF00180.20 CRK22958.1 - 8.1e-84 281.7 0.0 9.1e-84 281.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Glyco_hydro_28 PF00295.17 CRK22959.1 - 6.9e-12 45.1 7.4 1.4e-09 37.5 0.7 2.4 1 1 0 2 2 2 2 Glycosyl hydrolases family 28 Beta_helix PF13229.6 CRK22959.1 - 0.0014 18.5 9.7 0.18 11.6 9.8 2.6 1 1 0 1 1 1 1 Right handed beta helix region CdiI_N PF18228.1 CRK22959.1 - 0.13 12.1 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 CdiI N-terminal domain Peptidase_S10 PF00450.22 CRK22961.1 - 5.4e-73 246.8 0.1 6.8e-73 246.5 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Sugar_tr PF00083.24 CRK22963.1 - 1.1e-106 357.4 15.6 1.4e-106 357.1 15.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK22963.1 - 2.9e-21 75.8 37.1 2e-20 73.1 19.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF554 PF04474.12 CRK22963.1 - 0.011 15.2 0.9 0.011 15.2 0.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF554) MFS_3 PF05977.13 CRK22963.1 - 0.24 9.8 6.6 0.066 11.6 2.7 1.8 2 0 0 2 2 2 0 Transmembrane secretion effector Phage_holin_2_3 PF16080.5 CRK22963.1 - 9.8 6.0 8.2 1.5 8.6 0.3 3.1 3 0 0 3 3 3 0 Bacteriophage holin family HP1 Fungal_trans PF04082.18 CRK22965.1 - 1.7e-11 43.6 0.0 3.9e-11 42.5 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK22965.1 - 2.4e-09 37.2 9.9 4.1e-09 36.4 9.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 CRK22968.1 - 1.7e-19 70.0 12.2 2.3e-19 69.5 12.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Dala_Dala_lig_C PF07478.13 CRK22970.1 - 4.4e-10 39.4 0.0 6.2e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 CRK22970.1 - 0.00017 21.7 0.0 0.00025 21.1 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 CRK22970.1 - 0.00027 20.6 0.1 0.001 18.7 0.1 1.9 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 CRK22970.1 - 0.00033 20.2 0.0 0.00087 18.8 0.0 1.7 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain GARS_A PF01071.19 CRK22970.1 - 0.00055 19.8 0.0 0.00079 19.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Cu_amine_oxid PF01179.20 CRK22972.1 - 9e-134 446.4 0.0 1.2e-133 446.1 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 CRK22972.1 - 4.2e-10 39.7 0.1 7.5e-10 38.9 0.1 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 CRK22972.1 - 0.00068 20.0 0.0 0.0017 18.7 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Pox_F16 PF04708.12 CRK22974.1 - 0.0031 17.0 0.1 0.0034 16.9 0.1 1.1 1 0 0 1 1 1 1 Poxvirus F16 protein DUF1798 PF08807.10 CRK22974.1 - 0.051 13.7 0.8 0.057 13.6 0.8 1.0 1 0 0 1 1 1 0 Bacterial domain of unknown function (DUF1798) SET PF00856.28 CRK22977.1 - 2.5e-08 34.5 0.0 7.3e-08 33.0 0.0 1.8 1 1 0 1 1 1 1 SET domain DnaJ PF00226.31 CRK22980.1 - 8.1e-11 41.9 3.7 1.1e-10 41.4 2.0 2.0 2 1 0 2 2 2 1 DnaJ domain Leuk-A4-hydro_C PF09127.11 CRK22980.1 - 0.079 13.1 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Leukotriene A4 hydrolase, C-terminal Aldedh PF00171.22 CRK22981.1 - 2.2e-35 122.1 0.0 2.4e-35 121.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GAIN PF16489.5 CRK22981.1 - 0.046 13.1 0.0 0.056 12.9 0.0 1.1 1 0 0 1 1 1 0 GPCR-Autoproteolysis INducing (GAIN) domain DUF2626 PF11117.8 CRK22982.1 - 0.018 15.7 3.5 0.018 15.7 3.5 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2626) CDP-OH_P_tran_2 PF08009.11 CRK22982.1 - 0.17 11.8 0.6 0.17 11.8 0.6 2.3 2 0 0 2 2 2 0 CDP-alcohol phosphatidyltransferase 2 Proteasome PF00227.26 CRK22986.1 - 2.5e-26 92.4 0.0 3e-26 92.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Hpt PF01627.23 CRK22987.1 - 2.1e-08 34.3 0.1 2.4e-08 34.1 0.1 1.1 1 0 0 1 1 1 1 Hpt domain WD40 PF00400.32 CRK22989.1 - 2.1e-22 79.0 8.0 1e-07 32.5 0.1 4.2 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK22989.1 - 5.3e-07 29.8 0.0 0.06 13.6 0.0 2.8 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Abhydrolase_3 PF07859.13 CRK22990.1 - 9.7e-12 45.2 0.0 1.2e-11 44.8 0.0 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold Phosphorylase PF00343.20 CRK22992.1 - 2.9e-264 878.7 4.3 2.4e-190 634.4 0.4 2.0 1 1 1 2 2 2 2 Carbohydrate phosphorylase Pkinase PF00069.25 CRK22992.1 - 6.7e-46 156.8 0.0 1.2e-45 156.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK22992.1 - 1.3e-26 93.4 0.0 2.4e-26 92.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CRK22992.1 - 3.4e-05 23.0 0.0 6.1e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CRK22992.1 - 0.00013 21.4 0.1 0.00044 19.7 0.1 1.9 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CRK22992.1 - 0.0016 18.4 0.4 0.005 16.8 0.0 2.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CRK22992.1 - 0.0085 15.4 0.0 0.28 10.4 0.0 2.3 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.22 CRK22992.1 - 0.051 13.2 0.0 0.13 11.8 0.0 1.7 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 CRK22992.1 - 0.067 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Avl9 PF09794.9 CRK22994.1 - 7.8e-130 433.0 0.0 1.1e-129 432.4 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 Pkinase PF00069.25 CRK22994.1 - 2.1e-22 79.8 0.0 3.2e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain DUF2347 PF09804.9 CRK22994.1 - 4.6e-07 29.7 0.0 1.3e-05 25.0 0.0 2.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) SPA PF08616.10 CRK22994.1 - 1.1e-05 25.3 0.1 0.00071 19.5 0.0 2.5 2 0 0 2 2 2 1 Stabilization of polarity axis Avl9 PF09794.9 CRK22995.1 - 1.4e-140 468.3 0.0 2e-140 467.8 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.9 CRK22995.1 - 6.7e-07 29.2 0.4 2.4e-05 24.1 0.0 3.0 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) SPA PF08616.10 CRK22995.1 - 4e-05 23.5 0.1 0.0013 18.7 0.0 2.3 2 0 0 2 2 2 1 Stabilization of polarity axis HD-ZIP_N PF04618.12 CRK22995.1 - 0.69 10.4 4.3 9.8 6.7 0.5 3.0 2 0 0 2 2 2 0 HD-ZIP protein N terminus SNF2_N PF00176.23 CRK22996.1 - 2.8e-129 430.8 0.3 2.9e-72 243.3 0.1 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 CRK22996.1 - 6.6e-30 103.7 0.0 1.4e-12 47.9 0.0 4.6 4 0 0 4 4 4 2 Helicase conserved C-terminal domain zf-RING_5 PF14634.6 CRK22996.1 - 1.3e-13 50.6 18.0 1.4e-06 28.1 5.1 2.4 2 0 0 2 2 2 2 zinc-RING finger domain DEAD PF00270.29 CRK22996.1 - 4.6e-11 42.8 0.0 6.3e-05 22.8 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 CRK22996.1 - 9.7e-05 21.7 0.0 0.49 9.6 0.0 2.4 2 0 0 2 2 2 2 ERCC3/RAD25/XPB C-terminal helicase Prok-RING_4 PF14447.6 CRK22996.1 - 0.0037 17.1 13.3 0.32 10.9 2.9 2.7 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 CRK22996.1 - 0.0068 16.3 16.4 0.48 10.4 4.3 3.0 2 2 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CRK22996.1 - 0.008 16.0 12.4 0.62 10.0 2.5 3.0 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Fe_hyd_lg_C PF02906.14 CRK22996.1 - 0.042 13.5 3.8 4.1 7.0 0.3 2.5 2 0 0 2 2 2 0 Iron only hydrogenase large subunit, C-terminal domain WAK_assoc PF14380.6 CRK22996.1 - 0.045 14.5 0.3 21 5.9 0.0 2.6 2 0 0 2 2 2 0 Wall-associated receptor kinase C-terminal Swi3 PF07962.12 CRK22996.1 - 0.078 13.0 0.0 32 4.6 0.0 3.2 2 0 0 2 2 2 0 Replication Fork Protection Component Swi3 CelTOS PF18659.1 CRK22996.1 - 0.089 13.2 0.0 27 5.2 0.0 2.7 2 0 0 2 2 2 0 Cell-traversal protein for ookinetes and sporozoites HIRAN PF08797.11 CRK22996.1 - 0.13 12.2 0.0 0.34 10.9 0.0 1.7 1 0 0 1 1 1 0 HIRAN domain Myb_DNA-bind_7 PF15963.5 CRK22996.1 - 0.71 9.8 2.5 18 5.3 0.2 3.3 3 0 0 3 3 3 0 Myb DNA-binding like zf-RING_10 PF16685.5 CRK22996.1 - 1.4 9.1 8.3 13 6.0 1.1 2.9 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-RING_2 PF13639.6 CRK22996.1 - 2.6 8.4 14.2 9.2 6.7 3.3 2.7 2 0 0 2 2 2 0 Ring finger domain zf-RING_UBOX PF13445.6 CRK22996.1 - 8.1 6.6 9.9 20 5.3 1.6 2.6 2 0 0 2 2 2 0 RING-type zinc-finger DUF3679 PF12438.8 CRK22998.1 - 0.059 13.1 0.1 0.25 11.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3679) QWRF PF04484.12 CRK23000.1 - 0.82 9.4 11.3 1.1 8.9 11.3 1.3 1 0 0 1 1 1 0 QWRF family FRG2 PF15315.6 CRK23000.1 - 1.3 9.2 20.9 1.6 8.9 20.9 1.1 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 CNDH2_M PF16869.5 CRK23000.1 - 2.5 8.8 6.5 0.88 10.3 2.9 2.0 1 1 1 2 2 2 0 PF16858 SP_C-Propep PF08999.10 CRK23002.1 - 7.8 6.4 10.7 1.5e+03 -1.0 10.7 2.1 1 1 0 1 1 1 0 Surfactant protein C, N terminal propeptide PI3_PI4_kinase PF00454.27 CRK23004.1 - 4.4e-45 154.4 0.0 6.1e-45 154.0 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Methyltransf_23 PF13489.6 CRK23006.1 - 8.6e-12 45.2 0.0 1.3e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK23006.1 - 3.9e-10 40.3 0.0 8.4e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CRK23006.1 - 4.3e-06 27.3 0.0 7.9e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK23006.1 - 0.00015 21.6 0.0 0.00058 19.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK23006.1 - 0.00015 22.5 0.0 0.00027 21.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 CRK23006.1 - 0.0014 18.1 0.0 0.0029 17.1 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_2 PF00891.18 CRK23006.1 - 0.028 13.7 0.0 0.043 13.1 0.0 1.5 1 1 0 1 1 1 0 O-methyltransferase domain Methyltransf_16 PF10294.9 CRK23006.1 - 0.15 11.7 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase Ubie_methyltran PF01209.18 CRK23006.1 - 0.19 11.1 0.0 0.32 10.3 0.0 1.4 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family GCP_C_terminal PF04130.13 CRK23010.1 - 5.5e-61 206.7 3.9 9.6e-61 205.9 3.9 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 CRK23010.1 - 3.6e-35 122.1 0.0 1.1e-31 110.6 0.0 2.7 1 1 1 2 2 2 2 Gamma tubulin complex component N-terminal Proteasome PF00227.26 CRK23013.1 - 9.1e-56 188.4 0.2 1.2e-55 188.0 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CRK23013.1 - 1.3e-12 47.2 0.0 3.6e-12 45.7 0.0 1.9 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Fungal_trans_2 PF11951.8 CRK23015.1 - 1e-17 64.0 1.3 1.3e-10 40.7 0.4 3.1 3 0 0 3 3 3 3 Fungal specific transcription factor domain Methyltransf_8 PF05148.15 CRK23017.1 - 4e-52 177.2 0.0 4.7e-51 173.7 0.0 2.4 1 1 1 2 2 2 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 CRK23017.1 - 0.0017 18.9 0.0 0.0066 17.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK23017.1 - 0.009 16.7 0.0 0.39 11.5 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 CRK23017.1 - 1.9 8.4 0.0 1.9 8.4 0.0 2.7 3 1 0 3 3 3 0 Methyltransferase domain Asp_protease PF09668.10 CRK23019.1 - 3.2e-60 201.4 0.6 4.9e-60 200.8 0.6 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CRK23019.1 - 1.1e-23 83.5 0.4 2.5e-23 82.5 0.1 1.7 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CRK23019.1 - 4.1e-11 43.4 0.1 8.9e-11 42.3 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease ubiquitin PF00240.23 CRK23019.1 - 1.4e-07 31.2 0.0 2.8e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 CRK23019.1 - 2.2e-07 30.6 0.1 6.6e-07 29.1 0.1 1.9 1 0 0 1 1 1 1 UBA/TS-N domain RVP_2 PF08284.11 CRK23019.1 - 3e-05 23.8 0.0 6.8e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.20 CRK23019.1 - 0.00016 21.9 0.0 0.00044 20.5 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Ubiquitin_2 PF14560.6 CRK23019.1 - 0.0073 16.7 0.0 0.017 15.6 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-like domain DUF3577 PF12101.8 CRK23019.1 - 0.028 14.2 0.1 0.82 9.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3577) Rad60-SLD PF11976.8 CRK23019.1 - 0.033 14.0 0.0 0.066 13.1 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like UBA_4 PF14555.6 CRK23019.1 - 0.19 11.6 0.5 0.91 9.4 0.5 2.3 1 1 1 2 2 2 0 UBA-like domain Acetyltransf_1 PF00583.25 CRK23022.1 - 8.6e-09 35.7 0.0 1.3e-08 35.1 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CRK23022.1 - 2.1e-08 34.2 0.0 3.6e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CRK23022.1 - 5.6e-07 29.9 0.0 8.7e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain NOG1_N PF17835.1 CRK23023.1 - 6.4e-47 159.5 0.0 6.4e-47 159.5 0.0 2.1 3 0 0 3 3 3 1 NOG1 N-terminal helical domain MMR_HSR1 PF01926.23 CRK23023.1 - 3.3e-12 46.5 0.0 5.9e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase NOGCT PF08155.11 CRK23023.1 - 1.4e-10 41.0 3.0 3.3e-10 39.8 3.0 1.7 1 0 0 1 1 1 1 NOGCT (NUC087) domain FeoB_N PF02421.18 CRK23023.1 - 2.1e-05 24.1 0.0 4.1e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B NTP_transf_6 PF06042.11 CRK23023.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Nucleotidyltransferase MRP-L47 PF06984.13 CRK23025.1 - 9.6e-21 73.7 0.3 1.5e-20 73.1 0.3 1.3 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Clc-like PF07062.12 CRK23025.1 - 0.032 13.7 0.9 0.052 13.0 0.9 1.3 1 0 0 1 1 1 0 Clc-like Fungal_trans PF04082.18 CRK23029.1 - 4.9e-13 48.7 0.7 8.4e-13 48.0 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 CRK23029.1 - 9.8e-07 28.9 6.6 1.9e-05 24.9 1.1 2.7 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CRK23029.1 - 0.001 19.7 15.1 0.066 14.1 5.8 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.12 CRK23029.1 - 0.0016 18.7 4.4 0.0016 18.7 4.4 1.9 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 CRK23029.1 - 0.21 11.9 3.1 9.2 6.7 0.8 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 CRK23029.1 - 0.39 11.3 14.6 0.39 11.3 7.3 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type Actin PF00022.19 CRK23032.1 - 9.2e-17 60.7 0.0 2.8e-13 49.3 0.0 3.0 3 0 0 3 3 3 2 Actin MreB_Mbl PF06723.13 CRK23032.1 - 0.0086 14.9 0.0 0.2 10.5 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 CRK23032.1 - 0.04 14.4 0.0 0.11 12.9 0.0 1.9 1 1 0 1 1 1 0 Cell division protein FtsA Ysc84 PF04366.12 CRK23034.1 - 2.8e-29 101.4 0.0 4.8e-29 100.7 0.0 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator CENP-B_dimeris PF09026.10 CRK23034.1 - 0.093 13.1 7.3 0.3 11.5 7.3 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain TFIIA PF03153.13 CRK23034.1 - 0.1 12.6 11.9 0.01 15.9 7.4 1.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Cwf_Cwc_15 PF04889.12 CRK23034.1 - 0.64 9.7 12.5 1.3 8.7 12.5 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SUN PF03856.13 CRK23039.1 - 1.8e-40 138.9 0.9 2e-40 138.8 0.9 1.0 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) DUF3913 PF13052.6 CRK23039.1 - 0.21 11.9 1.7 9 6.7 0.1 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF3913) Putative_PNPOx PF01243.20 CRK23042.1 - 8e-06 26.0 0.0 0.00015 21.9 0.0 2.0 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase Mtc PF03820.17 CRK23045.1 - 0.09 11.8 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Tricarboxylate carrier ATP-synt_C PF00137.21 CRK23049.1 - 6.4e-18 64.9 35.4 6.5e-16 58.4 6.2 3.1 2 1 0 2 2 2 2 ATP synthase subunit C CNH PF00780.22 CRK23050.1 - 2.2e-12 47.2 0.0 2.7e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 CNH domain DUF4336 PF14234.6 CRK23053.1 - 3.8e-15 55.9 0.0 1.7e-08 34.1 0.0 2.6 1 1 1 2 2 2 2 Domain of unknown function (DUF4336) Nse4_C PF08743.10 CRK23055.1 - 1.7e-21 76.2 0.0 8.3e-21 74.1 0.0 2.3 1 0 0 1 1 1 1 Nse4 C-terminal FPP PF05911.11 CRK23055.1 - 0.0016 16.7 1.3 0.0016 16.7 1.3 3.2 2 1 1 3 3 3 2 Filament-like plant protein, long coiled-coil EIAV_Rev PF11129.8 CRK23055.1 - 0.031 14.5 0.5 0.031 14.5 0.5 2.9 2 1 0 2 2 2 0 Rev protein of equine infectious anaemia virus RPW8 PF05659.11 CRK23055.1 - 3.7 7.2 14.2 4.7 6.9 2.6 3.7 3 0 0 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 WXG100 PF06013.12 CRK23055.1 - 5 7.4 16.3 18 5.7 2.9 5.1 4 1 0 4 4 4 0 Proteins of 100 residues with WXG PI3Ka PF00613.20 CRK23057.1 - 1.5e-56 190.7 1.1 2.4e-56 190.1 1.1 1.2 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 CRK23057.1 - 1.9e-46 158.9 0.3 1.5e-43 149.5 0.1 2.6 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 CRK23057.1 - 5.7e-24 84.6 0.0 1e-23 83.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 ADH_zinc_N PF00107.26 CRK23059.1 - 3.9e-14 52.7 0.0 6.6e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CRK23059.1 - 0.00028 22.0 0.0 0.00049 21.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase HTH_23 PF13384.6 CRK23059.1 - 0.021 14.6 0.0 0.051 13.4 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain UQ_con PF00179.26 CRK23062.1 - 1e-47 161.3 0.0 1.1e-47 161.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CRK23062.1 - 0.00052 19.7 0.0 0.00071 19.3 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 CRK23062.1 - 0.0043 16.9 0.1 0.008 16.0 0.1 1.5 1 1 0 1 1 1 1 UEV domain RWD PF05773.22 CRK23062.1 - 0.074 13.3 0.0 0.093 13.0 0.0 1.3 1 0 0 1 1 1 0 RWD domain WD40 PF00400.32 CRK23064.1 - 7.7e-09 36.1 14.1 0.0032 18.3 0.3 5.3 4 0 0 4 4 4 3 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 CRK23064.1 - 3e-06 26.8 11.7 3e-06 26.8 11.7 3.5 3 0 0 3 3 3 1 Zinc-ribbon, C4HC2 type RWD PF05773.22 CRK23064.1 - 0.028 14.7 0.0 0.065 13.5 0.0 1.5 1 0 0 1 1 1 0 RWD domain TauD PF02668.16 CRK23066.1 - 7.7e-31 107.9 0.4 1e-30 107.4 0.4 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 CRK23066.1 - 0.037 13.1 0.0 0.083 12.0 0.0 1.5 2 0 0 2 2 2 0 CsiD AA_permease_2 PF13520.6 CRK23069.1 - 2.3e-69 234.3 38.8 2.9e-69 234.0 38.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CRK23069.1 - 3.3e-13 49.0 38.0 7.7e-13 47.8 38.0 1.5 1 1 0 1 1 1 1 Amino acid permease LPMO_10 PF03067.15 CRK23071.1 - 2.1e-09 38.3 0.0 3.2e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading bZIP_2 PF07716.15 CRK23071.1 - 3.7 7.7 11.2 5.8 7.1 11.2 1.2 1 0 0 1 1 1 0 Basic region leucine zipper Glyco_hydro_43 PF04616.14 CRK23073.1 - 4.6e-57 193.5 5.5 6.1e-56 189.9 1.1 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 43 AA_permease_2 PF13520.6 CRK23075.1 - 1.5e-71 241.5 38.5 1.9e-71 241.2 38.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CRK23075.1 - 1.7e-12 46.7 38.5 6.5e-12 44.8 38.5 1.7 1 1 0 1 1 1 1 Amino acid permease PepSY_TM PF03929.16 CRK23075.1 - 0.91 9.1 6.4 17 5.0 0.1 2.8 2 1 0 2 2 2 0 PepSY-associated TM region LPMO_10 PF03067.15 CRK23077.1 - 3.7e-09 37.5 0.0 6e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Herpes_DNAp_acc PF04929.12 CRK23077.1 - 0.28 10.1 5.9 0.4 9.6 5.9 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor bZIP_2 PF07716.15 CRK23077.1 - 3.6 7.7 11.2 5.7 7.1 11.2 1.2 1 0 0 1 1 1 0 Basic region leucine zipper Glyco_hydro_43 PF04616.14 CRK23079.1 - 6.9e-64 215.9 6.4 1.7e-55 188.4 1.2 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.20 CRK23079.1 - 1.1e-10 41.6 2.1 0.0001 22.0 0.8 2.8 2 0 0 2 2 2 2 Glycosyl hydrolases family 32 N-terminal domain Mid2 PF04478.12 CRK23081.1 - 2.9e-06 27.2 0.4 2.9e-06 27.2 0.4 2.7 3 1 0 3 3 3 1 Mid2 like cell wall stress sensor Ndc1_Nup PF09531.10 CRK23081.1 - 0.65 8.6 8.6 0.79 8.3 8.6 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SKG6 PF08693.10 CRK23081.1 - 3.8 7.0 7.1 0.29 10.6 1.5 2.1 2 0 0 2 2 2 0 Transmembrane alpha-helix domain HutP PF09021.11 CRK23083.1 - 0.18 12.1 0.5 0.54 10.6 0.5 1.7 1 0 0 1 1 1 0 HutP PAM2 PF07145.15 CRK23083.1 - 2.9 7.8 13.9 5.2 7.0 1.6 5.3 5 0 0 5 5 5 0 Ataxin-2 C-terminal region SRP54 PF00448.22 CRK23084.1 - 5e-53 179.7 1.5 6.7e-53 179.2 0.2 1.8 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.13 CRK23084.1 - 3.8e-10 40.2 2.1 5.5e-10 39.7 2.1 1.3 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54_N PF02881.19 CRK23084.1 - 6.2e-09 36.0 0.2 1.4e-08 34.8 0.2 1.6 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 CRK23084.1 - 1.5e-07 30.7 0.1 2.8e-07 29.8 0.1 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 CRK23084.1 - 0.00013 21.8 0.2 0.00031 20.5 0.2 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 CRK23084.1 - 0.00047 20.6 0.1 0.0012 19.3 0.1 1.6 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 CRK23084.1 - 0.0015 18.5 0.1 0.57 10.2 0.0 2.6 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.6 CRK23084.1 - 0.0026 17.9 0.1 0.024 14.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 CRK23084.1 - 0.0047 16.5 0.1 0.0082 15.7 0.1 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 CRK23084.1 - 0.0089 16.4 0.2 0.025 15.0 0.1 1.7 2 0 0 2 2 2 1 AAA ATPase domain FtsZ_C PF12327.8 CRK23084.1 - 0.0095 16.2 0.1 0.034 14.4 0.1 2.0 1 1 0 1 1 1 1 FtsZ family, C-terminal domain ABC_tran PF00005.27 CRK23084.1 - 0.024 15.1 0.1 0.077 13.5 0.0 1.9 2 1 0 2 2 2 0 ABC transporter MMR_HSR1 PF01926.23 CRK23084.1 - 0.026 14.6 0.4 0.15 12.1 0.4 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase SMC_N PF02463.19 CRK23084.1 - 0.044 13.2 0.0 0.069 12.6 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_24 PF13479.6 CRK23084.1 - 0.059 13.1 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain NAD_binding_10 PF13460.6 CRK23084.1 - 0.065 13.1 1.2 1.3 8.9 0.3 2.9 1 1 1 2 2 2 0 NAD(P)H-binding V-ATPase_C PF03223.15 CRK23102.1 - 7.9e-18 65.0 0.0 8.9e-18 64.8 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C COX1 PF00115.20 CRK23103.1 - 0.00097 18.1 7.9 0.00097 18.1 7.9 2.2 1 1 1 2 2 2 2 Cytochrome C and Quinol oxidase polypeptide I DUF872 PF05915.12 CRK23103.1 - 0.36 11.0 0.0 0.36 11.0 0.0 2.4 3 1 1 4 4 4 0 Eukaryotic protein of unknown function (DUF872) 4HBT PF03061.22 CRK23105.1 - 2.6e-14 53.3 0.2 4.8e-14 52.5 0.2 1.4 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 CRK23105.1 - 0.00084 19.5 0.0 0.0014 18.8 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4442) 4HBT_3 PF13622.6 CRK23105.1 - 0.0042 17.4 0.0 0.0053 17.0 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily Tfb2 PF03849.14 CRK23106.1 - 4e-123 410.9 0.0 4.8e-123 410.6 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 CRK23106.1 - 7.4e-22 77.6 2.0 1.4e-21 76.6 2.0 1.5 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 CRK23106.1 - 0.00012 22.3 0.0 0.00029 21.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TANGO2 PF05742.12 CRK23107.1 - 6.6e-65 219.6 0.0 9.4e-65 219.1 0.0 1.2 1 0 0 1 1 1 1 Transport and Golgi organisation 2 Toxin_10 PF05431.11 CRK23107.1 - 0.062 12.8 0.2 0.11 11.9 0.2 1.3 1 0 0 1 1 1 0 Insecticidal Crystal Toxin, P42 FAD_binding_4 PF01565.23 CRK23108.1 - 2.9e-21 75.7 0.5 6.8e-21 74.5 0.5 1.7 1 0 0 1 1 1 1 FAD binding domain MFS_5 PF05631.14 CRK23110.1 - 2.2e-28 99.2 0.0 3.8e-28 98.4 0.0 1.3 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 CRK23110.1 - 1.6e-11 43.7 7.2 1.6e-11 43.7 7.2 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK23110.1 - 0.0083 15.0 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 CRK23110.1 - 0.016 14.1 0.6 0.03 13.2 0.1 1.5 1 1 0 2 2 2 0 MFS_1 like family MFS_2 PF13347.6 CRK23110.1 - 0.03 12.9 0.3 0.047 12.2 0.3 1.3 1 0 0 1 1 1 0 MFS/sugar transport protein CCDC53 PF10152.9 CRK23110.1 - 0.26 11.7 4.1 0.82 10.1 0.2 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Glycogen_syn PF05693.13 CRK23111.1 - 0 1019.5 0.0 0 1019.2 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_transf_5 PF08323.11 CRK23111.1 - 8.9e-06 25.6 0.1 1.9e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_transf_4 PF13439.6 CRK23111.1 - 9.2e-06 25.8 0.1 2e-05 24.7 0.1 1.7 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 CRK23111.1 - 0.00041 19.9 0.0 0.024 14.1 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CRK23111.1 - 0.00081 19.8 0.0 0.54 10.7 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 CRK23111.1 - 0.00093 19.7 0.0 0.0024 18.3 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain TatC PF00902.18 CRK23112.1 - 0.03 14.1 0.0 0.067 13.0 0.0 1.4 1 1 0 1 1 1 0 Sec-independent protein translocase protein (TatC) F-box-like PF12937.7 CRK23113.1 - 2.2e-08 33.9 0.4 5.1e-08 32.7 0.4 1.7 1 0 0 1 1 1 1 F-box-like HP_OMP PF01856.17 CRK23113.1 - 0.25 11.4 0.0 0.52 10.4 0.0 1.5 1 0 0 1 1 1 0 Helicobacter outer membrane protein F-box PF00646.33 CRK23113.1 - 5.4 7.0 10.1 0.51 10.3 0.6 3.1 4 0 0 4 4 4 0 F-box domain Pkinase PF00069.25 CRK23115.1 - 3.2e-53 180.8 3.6 1.1e-34 120.0 0.0 2.5 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CRK23115.1 - 1e-36 126.6 0.0 2.7e-36 125.2 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CRK23115.1 - 0.0011 18.3 0.0 0.0031 16.9 0.0 1.7 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CRK23115.1 - 0.021 14.7 0.7 0.13 12.2 0.0 2.4 3 0 0 3 3 3 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CRK23115.1 - 0.048 12.4 1.1 0.091 11.5 0.0 1.9 2 0 0 2 2 2 0 Fungal protein kinase FapA PF03961.13 CRK23115.1 - 0.11 11.1 2.1 0.18 10.4 2.1 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF5446 PF17522.2 CRK23115.1 - 3.6 7.8 5.5 1.1 9.5 1.8 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5446) DUF3896 PF13035.6 CRK23115.1 - 4.1 7.6 7.7 0.66 10.2 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3896) OmpH PF03938.14 CRK23115.1 - 7 7.0 9.8 14 6.0 9.8 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) BTB PF00651.31 CRK23116.1 - 6e-24 84.4 0.8 2.2e-11 44.0 0.9 3.0 3 0 0 3 3 3 2 BTB/POZ domain Ank_2 PF12796.7 CRK23116.1 - 1.9e-07 31.6 0.0 4.2e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CRK23116.1 - 3.6e-06 27.1 0.0 9.5e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 CRK23116.1 - 5.1e-06 26.9 0.0 1.6e-05 25.4 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 CRK23116.1 - 3.8e-05 23.7 0.1 0.25 12.0 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 CRK23116.1 - 0.00029 21.1 0.0 0.12 12.8 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat PHD PF00628.29 CRK23117.1 - 3.1e-11 43.0 5.8 7.4e-11 41.8 5.8 1.7 1 0 0 1 1 1 1 PHD-finger PHD_4 PF16866.5 CRK23117.1 - 0.14 12.3 5.0 0.17 12.0 3.3 2.1 2 0 0 2 2 2 0 PHD-finger SCO1-SenC PF02630.14 CRK23120.1 - 5.1e-49 165.6 0.0 1.1e-48 164.5 0.0 1.6 2 0 0 2 2 2 1 SCO1/SenC Hydrolase_6 PF13344.6 CRK23120.1 - 1.4e-25 89.3 0.0 3e-25 88.3 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CRK23120.1 - 3.7e-19 68.6 0.0 1e-18 67.1 0.0 1.8 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 CRK23120.1 - 2.4e-07 31.2 0.0 0.57 10.4 0.0 4.0 2 1 2 4 4 4 2 haloacid dehalogenase-like hydrolase AhpC-TSA PF00578.21 CRK23120.1 - 0.00078 19.4 0.0 0.0022 17.9 0.0 1.8 1 0 0 1 1 1 1 AhpC/TSA family HAD_2 PF13419.6 CRK23120.1 - 0.0062 16.6 0.0 3 7.9 0.0 3.0 3 0 0 3 3 3 1 Haloacid dehalogenase-like hydrolase Redoxin PF08534.10 CRK23120.1 - 0.016 14.9 0.0 0.37 10.5 0.0 2.5 1 1 0 1 1 1 0 Redoxin Thioredoxin_8 PF13905.6 CRK23120.1 - 0.12 12.8 0.0 0.34 11.3 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin-like HAD PF12710.7 CRK23120.1 - 0.14 12.5 0.0 3.4 8.0 0.0 3.0 2 1 2 4 4 4 0 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CRK23120.1 - 0.19 11.5 0.0 0.37 10.5 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Choline_kin_N PF04428.14 CRK23122.1 - 3.4e-21 74.7 0.0 9.2e-21 73.3 0.0 1.8 2 0 0 2 2 2 1 Choline kinase N terminus Choline_kinase PF01633.20 CRK23122.1 - 1.9e-09 37.5 0.6 4.1e-09 36.3 0.0 1.8 2 0 0 2 2 2 1 Choline/ethanolamine kinase Macoilin PF09726.9 CRK23122.1 - 2.6 6.5 8.4 3.3 6.2 8.4 1.2 1 0 0 1 1 1 0 Macoilin family BRF1 PF07741.13 CRK23122.1 - 8.1 6.9 9.8 6.6 7.1 7.3 2.1 1 1 1 2 2 2 0 Brf1-like TBP-binding domain Peptidase_C14 PF00656.22 CRK23133.1 - 4.7e-20 72.6 0.0 5.4e-20 72.4 0.0 1.0 1 0 0 1 1 1 1 Caspase domain Kinesin PF00225.23 CRK23149.1 - 3.5e-43 147.8 0.1 3.8e-43 147.7 0.1 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CRK23149.1 - 3e-20 72.7 0.1 3.7e-20 72.4 0.1 1.1 1 0 0 1 1 1 1 Microtubule binding ERG2_Sigma1R PF04622.12 CRK23149.1 - 0.054 12.8 0.0 0.075 12.4 0.0 1.2 1 0 0 1 1 1 0 ERG2 and Sigma1 receptor like protein PhoH PF02562.16 CRK23149.1 - 0.15 11.5 0.1 0.2 11.1 0.1 1.3 1 1 0 1 1 1 0 PhoH-like protein adh_short PF00106.25 CRK23158.1 - 1.9e-20 73.1 0.0 2.2e-20 72.9 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK23158.1 - 2e-20 73.4 0.0 2.2e-20 73.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase WD40 PF00400.32 CRK23163.1 - 4.3e-22 78.0 17.3 2.2e-06 28.3 0.4 6.0 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK23163.1 - 3.6e-12 46.4 0.5 0.00038 20.7 0.1 4.1 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CRK23163.1 - 0.0012 17.6 0.8 14 4.2 0.0 4.2 4 1 1 5 5 5 3 Nucleoporin Nup120/160 Ago_hook PF10427.9 CRK23163.1 - 0.27 11.8 1.8 0.5 10.9 1.8 1.5 1 0 0 1 1 1 0 Argonaute hook Methyltransf_23 PF13489.6 CRK23164.1 - 8.6e-11 41.9 0.0 1.3e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK23164.1 - 1.9e-08 34.9 0.0 2.9e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CRK23164.1 - 9.1e-08 32.7 0.0 1.5e-07 32.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK23164.1 - 1.4e-05 25.7 0.0 2.5e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CRK23164.1 - 0.00025 20.4 0.0 0.00036 19.9 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 CRK23164.1 - 0.00048 19.9 0.0 0.00066 19.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.12 CRK23164.1 - 0.0039 17.0 0.0 0.0057 16.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_9 PF08003.11 CRK23164.1 - 0.058 12.3 0.0 0.084 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) PCMT PF01135.19 CRK23164.1 - 0.22 11.3 0.1 0.28 10.9 0.1 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) But2 PF09792.9 CRK23165.1 - 0.018 15.4 0.0 0.051 14.0 0.0 1.7 1 1 0 1 1 1 0 Ubiquitin 3 binding protein But2 C-terminal domain DnaJ PF00226.31 CRK23166.1 - 1.8e-26 92.0 3.0 3e-26 91.3 3.0 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 CRK23166.1 - 1.1e-25 90.5 0.0 1.6e-25 90.0 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 CRK23166.1 - 3e-14 53.1 16.6 4.8e-14 52.5 16.6 1.3 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 CRK23166.1 - 0.00099 19.1 9.0 0.048 13.7 1.4 2.2 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 CRK23166.1 - 0.003 17.5 8.1 0.38 10.7 1.2 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein TackOD1 PF18551.1 CRK23166.1 - 0.043 13.5 7.4 0.11 12.2 0.6 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 Snf7 PF03357.21 CRK23168.1 - 9.3e-32 110.0 54.4 5.4e-24 84.7 25.1 2.7 3 0 0 3 3 3 2 Snf7 Vps51 PF08700.11 CRK23168.1 - 7.3e-05 22.8 14.2 0.035 14.2 1.5 3.9 3 0 0 3 3 3 2 Vps51/Vps67 V-ATPase_G_2 PF16999.5 CRK23168.1 - 0.003 17.9 30.7 0.0074 16.7 10.4 3.4 3 1 1 4 4 4 2 Vacuolar (H+)-ATPase G subunit AvrPto PF11592.8 CRK23168.1 - 0.0054 16.7 1.8 0.041 13.9 0.3 2.4 2 0 0 2 2 2 1 Central core of the bacterial effector protein AvrPto FluMu_N PF17891.1 CRK23168.1 - 0.19 11.5 8.6 2 8.2 0.3 2.8 3 0 0 3 3 3 0 Mu-like prophage FluMu N-terminal domain MRP-L51 PF10244.9 CRK23168.1 - 0.43 10.8 8.2 5 7.4 0.8 2.6 2 1 0 2 2 2 0 Mitochondrial ribosomal subunit NPV_P10 PF05531.12 CRK23168.1 - 0.47 10.9 13.6 4.7 7.7 0.6 4.0 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF4748 PF15932.5 CRK23168.1 - 0.78 9.5 9.3 9.5 6.1 1.4 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4748) Baculo_8kDa PF06096.11 CRK23168.1 - 1.7 8.8 5.7 26 5.0 0.5 3.0 2 2 0 2 2 2 0 Baculoviridae 8.2 KDa protein DUF2935 PF11155.8 CRK23168.1 - 1.8 8.9 12.9 7.6 6.9 3.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) DUF5320 PF17253.2 CRK23168.1 - 2.8 9.1 11.5 17 6.6 0.1 4.3 4 1 0 4 4 4 0 Family of unknown function (DUF5320) TSC22 PF01166.18 CRK23168.1 - 3.7 7.9 10.4 11 6.4 0.7 3.4 3 0 0 3 3 3 0 TSC-22/dip/bun family Ten1 PF12658.7 CRK23169.1 - 6.1e-31 106.9 0.0 7e-31 106.7 0.0 1.0 1 0 0 1 1 1 1 Telomere capping, CST complex subunit Ten1_2 PF15490.6 CRK23169.1 - 2.9e-05 23.7 0.0 3.8e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit DUF554 PF04474.12 CRK23169.1 - 0.13 11.7 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF554) Ten1 PF12658.7 CRK23170.1 - 1.6e-30 105.5 0.0 1.8e-30 105.4 0.0 1.0 1 0 0 1 1 1 1 Telomere capping, CST complex subunit Ten1_2 PF15490.6 CRK23170.1 - 0.00013 21.6 0.0 0.00017 21.3 0.0 1.2 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit DUF3824 PF12868.7 CRK23172.1 - 6.9e-09 36.5 60.6 7.5e-07 29.9 44.1 9.6 4 3 2 7 7 7 4 Domain of unknwon function (DUF3824) ABA_WDS PF02496.16 CRK23172.1 - 0.033 14.7 15.0 0.61 10.6 0.9 3.6 3 0 0 3 3 3 0 ABA/WDS induced protein Helicase_C PF00271.31 CRK23173.1 - 2.3e-06 27.9 0.0 4.6e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ABA_WDS PF02496.16 CRK23173.1 - 7.5 7.1 7.3 9.3 6.8 3.3 2.7 2 0 0 2 2 2 0 ABA/WDS induced protein PC4 PF02229.16 CRK23174.1 - 2.8e-23 81.3 0.1 4.6e-23 80.6 0.1 1.4 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) A_deaminase PF00962.22 CRK23175.1 - 1.2e-12 47.8 0.0 1.6e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase TilS_C PF11734.8 CRK23175.1 - 0.082 12.3 0.0 0.27 10.7 0.0 1.8 1 1 0 1 1 1 0 TilS substrate C-terminal domain PRAP PF15314.6 CRK23175.1 - 0.12 12.9 0.0 0.3 11.6 0.0 1.6 1 0 0 1 1 1 0 Proline-rich acidic protein 1, pregnancy-specific uterine NmrA PF05368.13 CRK23176.1 - 3.9e-07 29.9 0.0 5.6e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 CRK23176.1 - 2.5e-06 27.5 0.0 3.8e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 CRK23176.1 - 0.07 13.4 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 CRK23176.1 - 0.096 12.8 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 CRK23176.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Ribosomal_L22e PF01776.17 CRK23177.1 - 3.1e-46 156.2 1.6 3.8e-46 156.0 1.6 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family START PF01852.19 CRK23177.1 - 0.011 15.1 0.0 0.016 14.7 0.0 1.1 1 0 0 1 1 1 0 START domain S4 PF01479.25 CRK23178.1 - 6.9e-12 44.9 0.0 1.5e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 CRK23178.1 - 1.4e-11 45.1 0.4 2.1e-11 44.6 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Herpes_LAMP2 PF06126.11 CRK23178.1 - 0.096 11.3 0.2 0.15 10.7 0.2 1.4 1 1 0 1 1 1 0 Herpesvirus Latent membrane protein 2 Ribosomal_S18 PF01084.20 CRK23179.1 - 6.4e-12 45.5 0.0 1e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S18 HTH_Tnp_1 PF01527.20 CRK23179.1 - 0.017 15.4 0.0 0.038 14.3 0.0 1.7 1 0 0 1 1 1 0 Transposase PPR_2 PF13041.6 CRK23180.1 - 4.3e-08 33.2 0.2 0.13 12.5 0.0 4.7 3 1 2 5 5 5 2 PPR repeat family PPR_3 PF13812.6 CRK23180.1 - 0.00012 22.1 0.0 0.32 11.1 0.0 4.4 4 0 0 4 4 4 1 Pentatricopeptide repeat domain PPR PF01535.20 CRK23180.1 - 0.00067 19.7 0.1 0.091 13.1 0.0 3.6 3 0 0 3 3 3 1 PPR repeat PPR_long PF17177.4 CRK23180.1 - 0.016 14.5 0.0 11 5.3 0.0 3.3 2 1 1 3 3 3 0 Pentacotripeptide-repeat region of PRORP PUFD PF16553.5 CRK23180.1 - 0.15 12.2 0.0 0.42 10.8 0.0 1.6 1 0 0 1 1 1 0 BCORL-PCGF1-binding domain PP-binding PF00550.25 CRK23181.1 - 0.026 14.9 0.0 0.028 14.8 0.0 1.0 1 0 0 1 1 1 0 Phosphopantetheine attachment site RPN7 PF10602.9 CRK23230.1 - 4.3e-18 65.6 0.0 4.9e-18 65.4 0.0 1.0 1 0 0 1 1 1 1 26S proteasome subunit RPN7 ELMO_CED12 PF04727.13 CRK23278.1 - 2.5e-51 174.3 0.0 4.1e-51 173.6 0.0 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family PH_12 PF16457.5 CRK23278.1 - 3.8e-26 92.2 0.0 7.2e-26 91.3 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain DUF3361 PF11841.8 CRK23278.1 - 1.1e-13 51.3 0.0 3e-13 50.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) Sugar_tr PF00083.24 CRK23279.1 - 1.8e-71 241.3 16.6 2.3e-71 241.0 16.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK23279.1 - 1.6e-15 57.0 19.9 2.1e-15 56.5 19.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1240 PF06836.12 CRK23279.1 - 0.13 12.8 0.2 0.13 12.8 0.2 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1240) DUF3425 PF11905.8 CRK23280.1 - 2.6e-19 69.4 0.0 5.1e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) WSN PF02206.18 CRK23280.1 - 0.044 13.7 0.0 0.078 12.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function Aldo_ket_red PF00248.21 CRK23281.1 - 4.1e-66 223.2 0.0 4.9e-66 222.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DsrD PF08679.11 CRK23281.1 - 0.043 14.1 0.0 0.098 12.9 0.0 1.6 1 0 0 1 1 1 0 Dissimilatory sulfite reductase D (DsrD) zf-CCCH PF00642.24 CRK23282.1 - 1.3e-08 34.5 18.0 5.4e-07 29.4 2.6 3.0 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 CRK23282.1 - 0.0045 17.7 2.2 0.41 11.4 0.2 2.4 2 0 0 2 2 2 2 Torus domain RRM_1 PF00076.22 CRK23282.1 - 0.0073 16.1 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 CRK23282.1 - 0.012 15.6 2.9 0.012 15.6 2.9 3.0 3 0 0 3 3 3 0 Zinc finger domain zf-CCCH_3 PF15663.5 CRK23282.1 - 0.058 13.6 2.3 0.38 11.0 0.1 2.4 2 1 0 2 2 2 0 Zinc-finger containing family SCRG1 PF15224.6 CRK23282.1 - 0.12 12.5 1.7 0.58 10.3 0.1 2.3 2 0 0 2 2 2 0 Scrapie-responsive protein 1 Oxysterol_BP PF01237.18 CRK23283.1 - 9.3e-31 107.0 0.4 3.6e-28 98.5 0.4 2.1 1 1 0 1 1 1 1 Oxysterol-binding protein DUF2417 PF10329.9 CRK23285.1 - 1.3e-83 280.1 3.8 1.7e-83 279.7 3.8 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_1 PF00561.20 CRK23285.1 - 0.094 12.3 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2070 PF09843.9 CRK23285.1 - 0.21 9.9 14.6 0.29 9.4 14.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) PGA2 PF07543.12 CRK23287.1 - 0.075 13.0 0.2 0.15 12.0 0.2 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 TFIIA PF03153.13 CRK23287.1 - 2 8.3 5.7 2.9 7.8 5.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit UQ_con PF00179.26 CRK23288.1 - 3.4e-40 136.9 0.0 9.4e-27 93.4 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CRK23288.1 - 0.0012 18.6 0.0 0.081 12.6 0.0 2.3 2 0 0 2 2 2 2 Prokaryotic E2 family B RWD PF05773.22 CRK23288.1 - 0.011 16.0 0.0 5.6 7.3 0.0 2.5 2 1 0 2 2 2 0 RWD domain Rep_fac_C PF08542.11 CRK23289.1 - 5.7e-20 71.5 0.0 1.1e-19 70.6 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_assoc_2 PF16193.5 CRK23289.1 - 9.5e-06 25.9 0.0 2.8e-05 24.4 0.0 1.9 1 0 0 1 1 1 1 AAA C-terminal domain DNA_pol3_delta PF06144.13 CRK23289.1 - 0.0012 18.7 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 CRK23289.1 - 0.0024 18.3 0.3 0.0099 16.3 0.0 2.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 CRK23289.1 - 0.023 14.6 0.0 0.048 13.6 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain Sec63 PF02889.16 CRK23291.1 - 1.4e-164 545.5 0.0 1.8e-93 312.5 0.0 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 CRK23291.1 - 1.7e-48 164.7 0.1 6.1e-28 97.8 0.0 2.9 3 0 0 3 3 3 2 DEAD/DEAH box helicase ORC3_N PF07034.11 CRK23291.1 - 1.3e-35 123.1 0.0 2.4e-33 115.7 0.0 2.8 2 1 0 2 2 2 1 Origin recognition complex (ORC) subunit 3 N-terminus Helicase_PWI PF18149.1 CRK23291.1 - 2e-33 114.9 1.2 7.1e-33 113.1 1.2 2.0 1 0 0 1 1 1 1 N-terminal helicase PWI domain ResIII PF04851.15 CRK23291.1 - 6.7e-23 81.5 0.0 3.2e-13 50.1 0.0 2.9 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit ORC_WH_C PF18137.1 CRK23291.1 - 5.1e-21 75.2 0.0 5.1e-21 75.2 0.0 5.9 5 2 0 5 5 5 1 Origin recognition complex winged helix C-terminal PWWP PF00855.17 CRK23291.1 - 1e-11 45.1 0.0 4.9e-11 42.9 0.0 2.3 1 0 0 1 1 1 1 PWWP domain Helicase_C PF00271.31 CRK23291.1 - 1.1e-08 35.4 0.0 7.5e-07 29.5 0.0 3.7 3 1 0 3 3 3 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 CRK23291.1 - 5.8e-07 29.9 0.6 0.0087 16.3 0.0 3.4 3 0 0 3 3 3 2 AAA domain T2SSE PF00437.20 CRK23291.1 - 0.013 14.5 0.0 2.8 6.9 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein Sec66 PF09802.9 CRK23294.1 - 4.8e-80 267.4 0.1 5.6e-80 267.2 0.1 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 DUF3848 PF12959.7 CRK23294.1 - 0.035 14.2 0.0 0.081 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3848) NPL4 PF05021.15 CRK23296.1 - 2.5e-137 457.3 0.0 3.3e-137 456.9 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 CRK23296.1 - 7.8e-67 223.9 0.1 1.3e-66 223.3 0.1 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 CRK23296.1 - 0.00044 20.7 0.0 0.00095 19.6 0.0 1.6 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 CPSase_L_D2 PF02786.17 CRK23298.1 - 8.3e-23 81.0 0.0 1.4e-22 80.2 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PheRS_DBD3 PF18553.1 CRK23298.1 - 3.1e-15 56.2 0.9 7.8e-15 54.9 0.9 1.8 1 0 0 1 1 1 1 PheRS DNA binding domain 3 ATP-grasp PF02222.22 CRK23298.1 - 2.3e-11 43.6 1.2 4.6e-11 42.6 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain CPSase_L_D3 PF02787.19 CRK23298.1 - 1.7e-09 38.0 0.7 7.2e-09 36.0 0.7 2.1 1 1 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Dala_Dala_lig_C PF07478.13 CRK23298.1 - 2.8e-09 36.8 0.1 6.5e-09 35.6 0.1 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 CRK23298.1 - 1.1e-05 25.2 0.0 3.3e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon PheRS_DBD2 PF18554.1 CRK23298.1 - 3e-05 23.9 5.2 6e-05 22.9 5.2 1.6 1 0 0 1 1 1 1 PheRS DNA binding domain 2 tRNA-synt_2d PF01409.20 CRK23298.1 - 0.00013 21.6 0.0 0.00022 20.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) GARS_A PF01071.19 CRK23298.1 - 0.014 15.1 0.1 0.038 13.7 0.1 1.8 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GSH-S_ATP PF02955.16 CRK23298.1 - 0.074 12.4 0.0 0.19 11.1 0.0 1.6 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain DUF1746 PF08508.10 CRK23300.1 - 1.2e-39 135.2 0.0 1.7e-39 134.7 0.0 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) RTC PF01137.21 CRK23302.1 - 1e-14 54.3 0.2 1.9e-13 50.1 0.1 1.9 1 1 1 2 2 2 2 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 CRK23302.1 - 4.8e-09 36.7 0.0 8.7e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain PPR_2 PF13041.6 CRK23304.1 - 2.8e-08 33.8 0.5 0.0011 19.1 0.0 4.4 6 0 0 6 6 6 2 PPR repeat family PPR PF01535.20 CRK23304.1 - 0.00048 20.2 0.0 1.6 9.1 0.0 3.8 3 0 0 3 3 3 2 PPR repeat PPR_3 PF13812.6 CRK23304.1 - 0.013 15.5 0.0 11 6.2 0.0 3.0 2 0 0 2 2 2 0 Pentatricopeptide repeat domain BTAD PF03704.17 CRK23304.1 - 0.024 15.1 0.1 34 4.9 0.0 3.9 4 0 0 4 4 4 0 Bacterial transcriptional activator domain PPR_1 PF12854.7 CRK23304.1 - 0.13 12.0 0.0 9.3 6.0 0.0 3.3 3 0 0 3 3 3 0 PPR repeat P4Ha_N PF08336.11 CRK23304.1 - 2.9 7.9 4.6 29 4.7 0.3 3.3 4 0 0 4 4 4 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Tnp_DNA_bind PF14706.6 CRK23306.1 - 0.018 14.9 0.2 0.34 10.8 0.0 2.3 2 0 0 2 2 2 0 Transposase DNA-binding CLLAC PF15675.5 CRK23306.1 - 0.024 14.2 0.6 0.047 13.3 0.6 1.4 1 0 0 1 1 1 0 CLLAC-motif containing domain RTC PF01137.21 CRK23307.1 - 8.4e-20 70.9 0.0 1.2e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase tRNA-synt_2d PF01409.20 CRK23307.1 - 3.5e-18 66.0 0.1 5.3e-18 65.4 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) RTC_insert PF05189.13 CRK23307.1 - 9.5e-11 42.1 0.0 2e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain Fungal_trans_2 PF11951.8 CRK23307.1 - 1.4e-08 34.0 0.1 2e-08 33.5 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain FANCI_S2 PF14676.6 CRK23319.1 - 0.014 15.7 0.0 0.018 15.3 0.0 1.2 1 0 0 1 1 1 0 FANCI solenoid 2 RPN6_N PF18055.1 CRK23319.1 - 0.031 14.6 0.0 0.054 13.9 0.0 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN6 N-terminal domain CsbD PF05532.12 CRK23322.1 - 6.5e-12 45.2 13.2 1.7e-11 43.8 5.6 2.3 1 1 1 2 2 2 2 CsbD-like WD40 PF00400.32 CRK23324.1 - 5.6e-14 52.3 0.4 9.7e-07 29.4 0.0 3.6 3 1 0 3 3 3 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 CRK23324.1 - 0.0077 15.2 0.2 0.058 12.4 0.2 2.0 1 1 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein VCBS PF13517.6 CRK23324.1 - 0.048 14.2 0.3 2.5 8.8 0.0 2.8 3 0 0 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella DUF2330 PF10092.9 CRK23324.1 - 0.14 11.2 0.0 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2330) Ras PF00071.22 CRK23328.1 - 3.6e-31 108.0 0.0 3.9e-31 107.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CRK23328.1 - 9.5e-24 83.9 0.0 1e-23 83.8 0.0 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CRK23328.1 - 9.2e-08 31.7 0.0 9.7e-08 31.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CRK23328.1 - 0.00017 21.0 0.0 0.0002 20.8 0.0 1.0 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CRK23328.1 - 0.021 14.9 0.0 0.024 14.7 0.0 1.1 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_7 PF12775.7 CRK23328.1 - 0.047 13.2 0.0 0.063 12.8 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 CRK23328.1 - 0.091 12.5 0.0 0.097 12.4 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CRK23328.1 - 0.095 13.0 0.0 0.095 13.0 0.0 1.2 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CRK23328.1 - 0.11 12.9 0.0 0.12 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 CRK23328.1 - 0.11 12.2 0.3 0.25 11.1 0.1 1.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_5 PF07728.14 CRK23328.1 - 0.17 11.9 0.0 0.17 11.9 0.0 1.2 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) MR_MLE_C PF13378.6 CRK23329.1 - 3.7e-45 154.2 0.4 5e-45 153.7 0.4 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 CRK23329.1 - 0.044 14.0 0.0 0.097 12.9 0.0 1.6 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain DHDPS PF00701.22 CRK23331.1 - 1.9e-42 145.0 0.0 2.2e-42 144.7 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family adh_short PF00106.25 CRK23332.1 - 1.7e-50 171.2 0.1 2.2e-50 170.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK23332.1 - 3.8e-34 118.2 0.1 5e-34 117.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK23332.1 - 2.8e-12 46.9 0.0 3.9e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 CRK23332.1 - 0.0022 17.2 0.1 0.028 13.5 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Rtt106_N PF18215.1 CRK23332.1 - 0.036 13.8 0.2 3 7.7 0.0 2.5 2 0 0 2 2 2 0 Histone chaperone Rtt106 N-terminal domain Eno-Rase_NADH_b PF12242.8 CRK23332.1 - 0.051 13.3 0.2 0.19 11.5 0.0 2.1 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RuvC PF02075.17 CRK23332.1 - 0.076 12.9 0.0 0.27 11.1 0.0 2.0 2 0 0 2 2 2 0 Crossover junction endodeoxyribonuclease RuvC Fungal_trans PF04082.18 CRK23333.1 - 1.3e-37 129.3 0.8 2.3e-37 128.5 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK23333.1 - 4.3e-08 33.2 11.8 8.1e-08 32.3 11.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tyrosinase PF00264.20 CRK23334.1 - 7.2e-47 160.5 0.0 9.4e-47 160.1 0.0 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF3537 PF12056.8 CRK23335.1 - 0.007 15.2 1.3 0.016 14.1 1.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3537) FtsL PF04999.13 CRK23335.1 - 1.6 8.7 3.6 16 5.5 0.0 3.0 3 0 0 3 3 3 0 Cell division protein FtsL G-patch PF01585.23 CRK23338.1 - 9.6e-13 47.8 3.5 2.4e-12 46.5 3.5 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 CRK23338.1 - 4e-07 30.0 1.4 4e-07 30.0 1.4 2.2 2 0 0 2 2 2 1 G-patch domain zf-RanBP PF00641.18 CRK23338.1 - 1.5e-06 27.4 1.6 3.2e-06 26.3 1.6 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others RRM_1 PF00076.22 CRK23338.1 - 3.1e-06 26.9 0.0 0.005 16.6 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MT0933_antitox PF14013.6 CRK23338.1 - 0.0031 17.8 0.1 0.011 16.1 0.1 2.0 1 0 0 1 1 1 1 MT0933-like antitoxin protein RED_N PF07808.13 CRK23338.1 - 0.016 14.8 0.1 0.016 14.8 0.1 2.6 3 0 0 3 3 3 0 RED-like protein N-terminal region zf-C2H2_2 PF12756.7 CRK23338.1 - 0.019 15.3 0.6 0.019 15.3 0.6 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 CRK23338.1 - 0.093 13.1 0.8 0.27 11.6 0.8 1.8 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding DUF3395 PF11875.8 CRK23340.1 - 1.6 8.6 5.1 2.7 7.8 5.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3395) DUF3433 PF11915.8 CRK23343.1 - 8.7e-36 122.3 14.3 2.8e-29 101.4 5.7 4.1 6 0 0 6 6 6 2 Protein of unknown function (DUF3433) ThiF PF00899.21 CRK23347.1 - 4.4e-40 137.6 0.0 6.8e-40 136.9 0.0 1.2 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 CRK23347.1 - 0.00011 22.5 0.0 0.00034 20.9 0.0 1.8 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 CRK23347.1 - 0.0026 18.0 0.4 0.039 14.2 0.0 2.8 2 1 0 2 2 2 1 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 CRK23347.1 - 0.039 13.5 0.1 0.068 12.7 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.6 CRK23347.1 - 0.048 14.1 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Amidase_6 PF12671.7 CRK23347.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative amidase domain Melibiase_2 PF16499.5 CRK23347.1 - 0.14 11.3 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Alpha galactosidase A Lipase_GDSL_2 PF13472.6 CRK23349.1 - 8.3e-17 62.1 0.0 1.1e-16 61.8 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 CRK23349.1 - 9.2e-08 32.3 0.0 1.4e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase FAD_binding_4 PF01565.23 CRK23351.1 - 2e-13 50.3 0.0 2.3e-13 50.1 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain AP_endonuc_2 PF01261.24 CRK23351.1 - 0.089 12.2 0.0 0.099 12.1 0.0 1.1 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel ALO PF04030.14 CRK23352.1 - 8.8e-53 179.8 0.0 1.2e-52 179.4 0.0 1.1 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 CRK23352.1 - 9.6e-06 25.4 0.1 1.8e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain CE2_N PF17996.1 CRK23352.1 - 0.026 14.5 0.1 0.047 13.7 0.1 1.4 1 0 0 1 1 1 0 Carbohydrate esterase 2 N-terminal zf-C2H2 PF00096.26 CRK23354.1 - 2.1e-10 40.5 11.7 2.1e-05 24.7 1.9 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CRK23354.1 - 5.1e-07 29.8 6.5 1.8e-05 24.9 1.9 3.5 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CRK23354.1 - 0.00034 21.2 16.7 0.013 16.3 1.6 2.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 CRK23354.1 - 0.0032 17.8 2.4 0.017 15.5 0.8 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 CRK23354.1 - 0.01 15.8 0.5 0.01 15.8 0.5 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CRK23354.1 - 0.019 15.2 2.6 0.12 12.7 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Zn_ribbon_SprT PF17283.2 CRK23354.1 - 0.047 13.6 1.1 0.047 13.6 1.1 2.3 1 1 1 2 2 2 0 SprT-like zinc ribbon domain Zn-ribbon_8 PF09723.10 CRK23354.1 - 0.049 13.8 2.1 0.39 10.9 0.7 2.2 1 1 1 2 2 2 0 Zinc ribbon domain DGF-1_C PF11040.8 CRK23354.1 - 0.58 10.2 3.0 1.5 8.9 3.0 1.7 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Ad_cyc_g-alpha PF08509.11 CRK23356.1 - 0.34 10.7 7.5 3 7.7 0.7 2.4 2 0 0 2 2 2 0 Adenylate cyclase G-alpha binding domain DDE_Tnp_1_2 PF13586.6 CRK23360.1 - 0.01 16.2 0.0 0.015 15.7 0.0 1.1 1 0 0 1 1 1 0 Transposase DDE domain zf-C2H2 PF00096.26 CRK23362.1 - 1e-09 38.3 11.7 5e-05 23.5 1.9 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CRK23362.1 - 5.3e-08 32.9 10.1 4.4e-05 23.7 1.9 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CRK23362.1 - 2.6e-05 24.7 11.0 0.032 15.1 1.6 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 CRK23362.1 - 0.012 16.0 2.4 0.041 14.3 0.8 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 CRK23362.1 - 0.025 14.6 0.5 0.025 14.6 0.5 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CRK23362.1 - 0.085 13.2 2.6 0.28 11.5 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 CRK23362.1 - 0.19 11.9 2.0 1.1 9.5 0.7 2.3 1 1 1 2 2 2 0 Zinc ribbon domain Zn_ribbon_SprT PF17283.2 CRK23362.1 - 0.24 11.4 6.4 0.12 12.3 1.1 2.5 1 1 1 2 2 2 0 SprT-like zinc ribbon domain Ad_cyc_g-alpha PF08509.11 CRK23362.1 - 4.3 7.1 7.5 12 5.7 0.7 2.6 2 0 0 2 2 2 0 Adenylate cyclase G-alpha binding domain Pkinase PF00069.25 CRK23365.1 - 3.3e-53 180.8 3.6 1.1e-34 120.0 0.0 2.5 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CRK23365.1 - 1e-36 126.6 0.0 2.7e-36 125.2 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CRK23365.1 - 0.0011 18.3 0.0 0.0031 16.9 0.0 1.7 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CRK23365.1 - 0.021 14.7 0.7 0.13 12.2 0.0 2.4 3 0 0 3 3 3 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CRK23365.1 - 0.05 12.4 1.2 0.091 11.5 0.0 1.9 2 0 0 2 2 2 0 Fungal protein kinase FapA PF03961.13 CRK23365.1 - 0.11 11.1 2.1 0.18 10.4 2.1 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF5446 PF17522.2 CRK23365.1 - 3.6 7.8 5.5 1.1 9.5 1.8 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5446) DUF3896 PF13035.6 CRK23365.1 - 4.1 7.7 7.7 0.66 10.2 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3896) OmpH PF03938.14 CRK23365.1 - 7 7.0 9.8 14 6.0 9.8 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) BTB PF00651.31 CRK23368.1 - 7.6e-24 84.1 0.4 3.7e-11 43.2 0.5 2.6 2 0 0 2 2 2 2 BTB/POZ domain Ank_2 PF12796.7 CRK23368.1 - 1.7e-07 31.8 0.0 3.8e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CRK23368.1 - 3.4e-06 27.2 0.0 8.7e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 CRK23368.1 - 4.8e-06 27.0 0.0 1.4e-05 25.5 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 CRK23368.1 - 3.3e-05 23.9 0.1 0.23 12.2 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 CRK23368.1 - 0.00029 21.1 0.0 0.11 12.9 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat PHD PF00628.29 CRK23369.1 - 3.1e-11 43.0 5.8 7.4e-11 41.8 5.8 1.7 1 0 0 1 1 1 1 PHD-finger PHD_4 PF16866.5 CRK23369.1 - 0.15 12.1 4.9 0.61 10.2 4.9 2.1 1 0 0 1 1 1 0 PHD-finger SCO1-SenC PF02630.14 CRK23371.1 - 1.2e-49 167.6 0.0 2.6e-49 166.6 0.0 1.6 2 0 0 2 2 2 1 SCO1/SenC Hydrolase_6 PF13344.6 CRK23371.1 - 1.7e-25 89.0 0.0 3.5e-25 88.0 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CRK23371.1 - 4.9e-19 68.2 0.0 1.3e-18 66.8 0.0 1.8 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 CRK23371.1 - 3.6e-08 34.0 0.0 0.13 12.5 0.0 4.0 2 1 1 3 3 3 3 haloacid dehalogenase-like hydrolase AhpC-TSA PF00578.21 CRK23371.1 - 0.0017 18.2 0.0 0.0044 16.9 0.0 1.7 1 0 0 1 1 1 1 AhpC/TSA family HAD_2 PF13419.6 CRK23371.1 - 0.0051 16.9 0.0 2.9 8.0 0.0 3.1 3 0 0 3 3 3 1 Haloacid dehalogenase-like hydrolase HAD PF12710.7 CRK23371.1 - 0.017 15.5 0.0 8.2 6.8 0.0 3.4 3 1 1 4 4 4 0 haloacid dehalogenase-like hydrolase Redoxin PF08534.10 CRK23371.1 - 0.046 13.4 0.0 0.92 9.2 0.0 2.5 1 1 0 1 1 1 0 Redoxin EAL PF00563.20 CRK23371.1 - 0.17 11.3 0.0 1.3 8.5 0.0 2.1 1 1 0 1 1 1 0 EAL domain Hydrolase_3 PF08282.12 CRK23371.1 - 0.19 11.5 0.0 0.37 10.5 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Choline_kinase PF01633.20 CRK23373.1 - 1e-81 273.6 0.0 3.4e-56 190.2 0.0 2.7 2 0 0 2 2 2 2 Choline/ethanolamine kinase Choline_kin_N PF04428.14 CRK23373.1 - 7.6e-21 73.5 0.0 2e-20 72.2 0.0 1.8 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.23 CRK23373.1 - 1e-06 28.8 1.0 0.014 15.3 0.1 3.5 3 1 0 3 3 3 2 Phosphotransferase enzyme family GCOM2 PF15328.6 CRK23373.1 - 0.037 14.4 6.5 0.079 13.3 6.5 1.6 1 0 0 1 1 1 0 Putative GRINL1B complex locus protein 2 ATP-synt_E_2 PF08112.11 CRK23373.1 - 0.044 14.0 0.0 19 5.6 0.0 2.5 2 0 0 2 2 2 0 ATP synthase epsilon subunit Macoilin PF09726.9 CRK23373.1 - 3.6 6.0 8.4 5.4 5.5 8.4 1.3 1 0 0 1 1 1 0 Macoilin family bZIP_2 PF07716.15 CRK23373.1 - 5 7.3 8.1 30 4.8 1.0 3.0 2 0 0 2 2 2 0 Basic region leucine zipper MoaE PF02391.17 CRK23375.1 - 2.2e-37 127.8 0.1 5.8e-37 126.4 0.1 1.8 1 0 0 1 1 1 1 MoaE protein Ribosomal_S14 PF00253.21 CRK23377.1 - 1.9e-27 94.8 7.5 6.7e-11 41.8 0.4 3.6 3 0 0 3 3 3 3 Ribosomal protein S14p/S29e FAD_binding_4 PF01565.23 CRK23377.1 - 9.7e-21 74.0 1.3 2e-20 72.9 1.3 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 CRK23377.1 - 1.4e-09 37.9 0.0 3.2e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like MoaE PF02391.17 CRK23377.1 - 3.8e-05 23.9 0.0 8.5e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 MoaE protein QLQ PF08880.11 CRK23377.1 - 0.0011 18.7 2.0 0.41 10.4 0.0 3.7 4 0 0 4 4 4 2 QLQ LBR_tudor PF09465.10 CRK23377.1 - 0.12 12.2 1.4 0.18 11.7 0.1 1.8 2 0 0 2 2 2 0 Lamin-B receptor of TUDOR domain SIP1 PF04938.12 CRK23380.1 - 6.4e-09 35.8 0.0 0.00084 19.1 0.0 3.3 3 0 0 3 3 3 3 Survival motor neuron (SMN) interacting protein 1 (SIP1) Ribosomal_S27e PF01667.17 CRK23381.1 - 3.5e-28 97.1 7.5 4.2e-28 96.8 7.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 TF_Zn_Ribbon PF08271.12 CRK23381.1 - 0.14 11.7 3.5 0.19 11.2 3.5 1.2 1 0 0 1 1 1 0 TFIIB zinc-binding zf-C2HC5 PF06221.13 CRK23381.1 - 1.2 9.2 7.0 2.7 8.0 4.3 2.3 2 1 0 2 2 2 0 Putative zinc finger motif, C2HC5-type LRR_8 PF13855.6 CRK23383.1 - 4.6e-06 26.3 1.1 1.4e-05 24.7 1.1 1.9 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 CRK23383.1 - 5.2e-05 23.5 0.3 0.00019 21.7 0.3 2.0 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CRK23383.1 - 0.093 13.3 3.8 8.3 7.4 0.8 3.8 3 0 0 3 3 3 0 Leucine Rich Repeat RTC PF01137.21 CRK23385.1 - 5.7e-41 140.1 0.0 1.2e-40 139.1 0.0 1.5 1 1 0 1 1 1 1 RNA 3'-terminal phosphate cyclase E_Pc_C PF06752.12 CRK23385.1 - 0.75 9.9 4.6 1.2 9.2 4.6 1.2 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus EST1_DNA_bind PF10373.9 CRK23389.1 - 2.4e-11 43.6 0.0 4.6e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain NFACT-C PF11923.8 CRK23392.1 - 9.5e-41 138.0 0.6 9.5e-41 138.0 0.6 4.7 5 0 0 5 5 5 1 NFACT protein C-terminal domain NFACT-R_1 PF05670.13 CRK23392.1 - 1.6e-32 112.4 0.0 3.2e-32 111.4 0.0 1.5 1 0 0 1 1 1 1 NFACT protein RNA binding domain FbpA PF05833.11 CRK23392.1 - 6.3e-27 94.4 7.6 6.3e-27 94.4 7.6 3.2 3 1 0 3 3 3 1 Fibronectin-binding protein A N-terminus (FbpA) NUDIX PF00293.28 CRK23394.1 - 1.8e-15 57.1 0.7 2.5e-15 56.7 0.7 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 CRK23394.1 - 0.011 15.7 0.3 0.024 14.6 0.3 1.6 1 1 0 1 1 1 0 NUDIX domain NFACT-C PF11923.8 CRK23395.1 - 1.5e-40 137.3 0.5 1.5e-40 137.3 0.5 4.4 5 0 0 5 5 5 1 NFACT protein C-terminal domain FbpA PF05833.11 CRK23395.1 - 4e-35 121.5 2.8 4e-35 121.5 2.8 2.3 2 0 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 CRK23395.1 - 1.5e-32 112.4 0.0 3.2e-32 111.4 0.0 1.6 1 0 0 1 1 1 1 NFACT protein RNA binding domain Zn_clus PF00172.18 CRK23395.1 - 8.1e-08 32.3 9.8 1.5e-07 31.4 9.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 CRK23395.1 - 0.0009 18.2 3.6 0.0017 17.2 3.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain eIF-5a PF01287.20 CRK23396.1 - 0.0002 21.4 0.0 0.00038 20.5 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold DUF4231 PF14015.6 CRK23396.1 - 5.2 7.6 4.8 4.3 7.8 2.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) EOS1 PF12326.8 CRK23396.1 - 7.1 6.5 7.9 0.33 10.9 0.1 2.4 2 1 0 2 2 2 0 N-glycosylation protein EOS1 PF12326.8 CRK23398.1 - 0.031 14.2 0.3 0.05 13.5 0.3 1.3 1 0 0 1 1 1 0 N-glycosylation protein MHYT PF03707.16 CRK23398.1 - 0.056 13.6 0.6 0.92 9.7 0.3 2.4 2 0 0 2 2 2 0 Bacterial signalling protein N terminal repeat DUF4231 PF14015.6 CRK23398.1 - 1.1 9.7 6.1 8.9 6.8 6.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) Jacalin PF01419.17 CRK23403.1 - 0.00088 19.2 0.0 2.5 8.0 0.0 2.7 2 0 0 2 2 2 2 Jacalin-like lectin domain BAF1_ABF1 PF04684.13 CRK23403.1 - 3.8 6.5 28.2 5.3 6.0 10.1 2.5 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Methyltransf_32 PF13679.6 CRK23404.1 - 0.15 12.0 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MT0933_antitox PF14013.6 CRK23405.1 - 2.1 8.7 9.9 7.2 7.0 7.7 2.7 2 1 0 2 2 2 0 MT0933-like antitoxin protein bVLRF1 PF18826.1 CRK23406.1 - 2.7e-62 209.1 0.0 7.4e-62 207.6 0.0 1.7 2 0 0 2 2 2 1 bacteroidetes VLRF1 release factor Ank_5 PF13857.6 CRK23406.1 - 7.3e-06 26.2 0.0 1.8e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) RPA43_OB PF17875.1 CRK23406.1 - 0.17 12.5 6.2 1.7 9.2 1.4 3.0 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I FTZ PF03867.14 CRK23406.1 - 0.2 11.2 1.2 0.42 10.1 1.2 1.4 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region CFEM PF05730.11 CRK23407.1 - 4.6e-05 23.4 2.1 4.6e-05 23.4 2.1 2.4 3 0 0 3 3 3 1 CFEM domain DUF2617 PF10936.8 CRK23408.1 - 0.08 13.0 0.0 1.5 8.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF2617 F-box-like PF12937.7 CRK23409.1 - 0.037 13.9 0.8 0.086 12.7 0.0 2.1 2 0 0 2 2 2 0 F-box-like Pyrid_oxidase_2 PF13883.6 CRK23410.1 - 1.9e-29 102.8 0.4 8.6e-27 94.2 0.4 2.9 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF3446 PF11928.8 CRK23410.1 - 0.0065 16.8 6.9 0.0065 16.8 6.9 3.2 3 0 0 3 3 3 2 Early growth response N-terminal domain Chorion_2 PF03964.15 CRK23410.1 - 0.25 12.2 8.4 4.6 8.1 3.3 2.5 2 0 0 2 2 2 0 Chorion family 2 Robl_LC7 PF03259.17 CRK23411.1 - 7.3e-11 41.7 1.4 2e-08 33.9 0.3 2.0 1 1 1 2 2 2 2 Roadblock/LC7 domain LAMTOR5 PF16672.5 CRK23411.1 - 0.043 13.8 0.1 0.087 12.8 0.1 1.4 1 0 0 1 1 1 0 Ragulator complex protein LAMTOR5 DEAD PF00270.29 CRK23412.1 - 5e-42 143.6 0.0 7.8e-42 143.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CRK23412.1 - 3.2e-27 95.1 0.0 1.2e-26 93.2 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 CRK23412.1 - 0.0019 17.0 0.0 0.0027 16.5 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain SecA_DEAD PF07517.14 CRK23412.1 - 0.13 11.6 0.1 1 8.6 0.0 2.0 2 0 0 2 2 2 0 SecA DEAD-like domain PhoLip_ATPase_C PF16212.5 CRK23413.1 - 6.6e-78 261.9 27.1 6.6e-78 261.9 27.1 2.7 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CRK23413.1 - 3.6e-19 68.2 0.4 9.2e-19 66.9 0.4 1.6 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 CRK23413.1 - 1.3e-13 50.8 0.0 5.7e-13 48.8 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CRK23413.1 - 1.7e-12 48.1 1.0 4.7e-08 33.6 0.4 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 CRK23413.1 - 0.00028 20.4 0.3 0.0015 18.1 0.0 2.3 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CRK23413.1 - 0.01 15.6 0.3 0.033 13.9 0.3 1.8 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Mg_trans_NIPA PF05653.14 CRK23414.1 - 3.6e-15 55.8 9.9 5.8e-15 55.2 9.9 1.2 1 0 0 1 1 1 1 Magnesium transporter NIPA PUNUT PF16913.5 CRK23414.1 - 0.0038 16.5 7.9 0.015 14.5 7.9 1.9 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport FAM178 PF14816.6 CRK23414.1 - 0.013 14.5 0.1 0.024 13.6 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function, FAM178 COX4_pro_2 PF07835.12 CRK23414.1 - 1.4 9.1 3.8 0.51 10.5 0.2 2.2 2 0 0 2 2 2 0 Bacterial aa3 type cytochrome c oxidase subunit IV FxsA PF04186.13 CRK23415.1 - 0.035 14.2 0.8 0.035 14.2 0.8 2.3 2 1 1 3 3 3 0 FxsA cytoplasmic membrane protein SRF-TF PF00319.18 CRK23416.1 - 1.4e-06 27.7 0.1 2.5e-06 26.9 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Ctr PF04145.15 CRK23417.1 - 1.3e-28 100.5 0.9 1.3e-28 100.5 0.9 1.6 2 0 0 2 2 2 1 Ctr copper transporter family zf-C2H2 PF00096.26 CRK23419.1 - 3.9e-10 39.6 15.3 2.7e-05 24.4 1.0 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CRK23419.1 - 1.8e-08 34.4 11.6 5.2e-06 26.6 1.8 2.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CRK23419.1 - 2.1e-07 31.2 15.0 0.00052 20.6 0.8 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CRK23419.1 - 0.00027 20.8 4.3 0.1 12.6 0.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CRK23419.1 - 0.00045 20.4 3.7 0.013 15.8 0.1 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 CRK23419.1 - 0.0074 16.0 10.3 0.29 10.9 0.9 2.6 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 CRK23419.1 - 0.15 11.9 2.4 4.2 7.2 0.2 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type BolA PF01722.18 CRK23419.1 - 0.19 12.0 4.9 8.3 6.8 0.0 3.0 2 1 1 3 3 3 0 BolA-like protein zf-met PF12874.7 CRK23419.1 - 0.59 10.6 4.3 0.66 10.5 0.1 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2HE PF16278.5 CRK23419.1 - 2.1 8.9 9.4 1.9 9.0 1.9 2.3 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Malate_synthase PF01274.22 CRK23422.1 - 4.3e-225 747.9 0.0 4.9e-225 747.8 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Malate_synthase PF01274.22 CRK23423.1 - 4e-225 748.0 0.0 4.6e-225 747.8 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Pkinase PF00069.25 CRK23424.1 - 2.5e-65 220.5 0.1 1.5e-64 218.0 0.1 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK23424.1 - 3.1e-35 121.7 0.1 1.3e-34 119.7 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Fungal_KA1 PF16797.5 CRK23424.1 - 5.3e-28 97.1 0.2 1.1e-27 96.1 0.2 1.5 1 0 0 1 1 1 1 Fungal kinase associated-1 domain Kinase-like PF14531.6 CRK23424.1 - 4.7e-06 26.1 0.0 7.4e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CRK23424.1 - 0.00027 20.3 0.2 0.00067 19.1 0.2 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CRK23424.1 - 0.00029 19.9 0.0 0.00047 19.2 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CRK23424.1 - 0.0024 17.8 0.0 0.024 14.6 0.0 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CRK23424.1 - 0.0025 17.4 0.5 0.0053 16.4 0.5 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 CRK23424.1 - 0.012 15.2 0.4 0.03 13.9 0.4 1.6 1 0 0 1 1 1 0 RIO1 family SMC_N PF02463.19 CRK23425.1 - 1.3e-27 96.7 0.0 2.3e-27 95.9 0.0 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CRK23425.1 - 7.4e-14 52.7 10.3 7.4e-14 52.7 10.3 4.9 3 2 0 3 3 1 1 AAA domain AAA_15 PF13175.6 CRK23425.1 - 2.2e-06 27.7 19.1 8.2e-05 22.5 0.0 3.6 2 2 1 3 3 3 2 AAA ATPase domain AAA_21 PF13304.6 CRK23425.1 - 6.1e-05 23.0 1.1 0.037 13.8 0.0 3.5 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CRK23425.1 - 0.0048 16.6 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATG16 PF08614.11 CRK23425.1 - 0.012 15.8 4.6 0.012 15.8 4.6 7.2 5 2 2 7 7 4 0 Autophagy protein 16 (ATG16) AAA PF00004.29 CRK23425.1 - 0.037 14.5 0.2 0.34 11.3 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DotD PF16816.5 CRK23425.1 - 0.046 13.7 0.0 0.38 10.7 0.0 2.7 1 0 0 1 1 1 0 DotD protein RsgA_GTPase PF03193.16 CRK23425.1 - 0.14 12.0 1.1 0.94 9.4 0.0 3.0 3 0 0 3 3 3 0 RsgA GTPase ABC_tran PF00005.27 CRK23425.1 - 0.16 12.5 0.1 0.16 12.5 0.1 4.8 3 2 0 3 3 2 0 ABC transporter AAA_27 PF13514.6 CRK23425.1 - 0.22 11.1 0.0 0.22 11.1 0.0 5.4 5 1 0 5 5 5 0 AAA domain DASH_Hsk3 PF08227.11 CRK23427.1 - 3.6e-20 72.0 3.5 4e-20 71.9 2.7 1.5 2 0 0 2 2 2 1 DASH complex subunit Hsk3 like BBS2_C PF14782.6 CRK23427.1 - 0.034 12.9 0.0 0.042 12.6 0.0 1.1 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal Rpr2 PF04032.16 CRK23428.1 - 1.1e-23 83.3 0.2 1.6e-23 82.8 0.2 1.2 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Glyco_hydro_28 PF00295.17 CRK23429.1 - 8.9e-50 169.6 0.0 1.4e-49 169.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 CRK23429.1 - 0.48 10.3 7.6 1.1 9.1 7.6 1.6 1 1 0 1 1 1 0 Right handed beta helix region Glyco_hydro_28 PF00295.17 CRK23430.1 - 7.9e-50 169.7 0.0 1.2e-49 169.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 CRK23430.1 - 0.69 9.8 8.2 1.6 8.5 8.2 1.6 1 1 0 1 1 1 0 Right handed beta helix region Pectinesterase PF01095.19 CRK23431.1 - 4.7e-18 64.9 0.0 7.5e-18 64.3 0.0 1.2 1 0 0 1 1 1 1 Pectinesterase INCA1 PF15142.6 CRK23431.1 - 0.17 11.9 0.0 0.26 11.3 0.0 1.2 1 0 0 1 1 1 0 INCA1 SEN1_N PF12726.7 CRK23433.1 - 7e-185 616.4 11.9 8.9e-185 616.1 11.9 1.1 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.6 CRK23433.1 - 2.6e-72 243.7 0.4 2.6e-72 243.7 0.4 2.7 3 1 0 3 3 2 1 AAA domain AAA_12 PF13087.6 CRK23433.1 - 1.4e-44 152.1 0.0 7.8e-44 149.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CRK23433.1 - 1.6e-09 37.8 0.6 9.4e-06 25.5 0.3 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 CRK23433.1 - 2.6e-09 37.5 0.0 1.3e-08 35.3 0.0 2.3 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 CRK23433.1 - 8.6e-05 22.4 0.1 0.058 13.1 0.0 3.3 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 CRK23433.1 - 0.00048 19.7 0.1 0.00048 19.7 0.1 3.7 2 2 0 2 2 1 1 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.14 CRK23433.1 - 0.05 13.5 0.2 2.1 8.2 0.0 2.9 2 1 0 2 2 2 0 Helicase AAA_22 PF13401.6 CRK23433.1 - 0.069 13.4 0.1 0.33 11.2 0.1 2.2 1 0 0 1 1 1 0 AAA domain CCDC144C PF14915.6 CRK23433.1 - 0.17 11.0 5.0 0.33 10.0 5.0 1.4 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region AAA_23 PF13476.6 CRK23433.1 - 0.29 11.6 6.9 0.033 14.7 0.5 2.6 2 1 0 2 2 2 0 AAA domain Utp21 PF04192.12 CRK23435.1 - 1.6e-81 273.2 0.0 2.3e-81 272.7 0.0 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 CRK23435.1 - 1.2e-13 51.3 13.4 1.1e-05 26.1 0.4 6.1 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK23435.1 - 3.2e-06 27.4 0.0 0.036 14.3 0.0 4.3 1 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CRK23435.1 - 0.00092 18.0 0.2 0.18 10.4 0.0 2.7 1 1 1 3 3 3 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 CRK23435.1 - 0.0098 14.5 0.0 0.02 13.4 0.0 1.4 1 0 0 1 1 1 1 Cytochrome D1 heme domain Nucleoporin_N PF08801.11 CRK23435.1 - 0.046 12.5 0.0 1.9 7.2 0.0 2.2 2 0 0 2 2 2 0 Nup133 N terminal like fn3_3 PF14686.6 CRK23436.1 - 9.1e-27 92.7 0.7 1.9e-26 91.6 0.7 1.6 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CBM-like PF14683.6 CRK23436.1 - 1.4e-25 90.0 0.0 2.6e-25 89.2 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III RhgB_N PF09284.10 CRK23436.1 - 0.0011 18.6 2.1 0.02 14.4 0.2 2.8 3 0 0 3 3 3 1 Rhamnogalacturonan lyase B, N-terminal CarboxypepD_reg PF13620.6 CRK23436.1 - 0.066 13.5 0.2 0.17 12.2 0.2 1.7 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain Glyco_hydro_76 PF03663.14 CRK23437.1 - 2.9e-45 155.4 7.3 2.9e-45 155.4 7.3 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 CRK23437.1 - 7e-07 28.6 0.6 0.0037 16.4 0.0 3.1 1 1 1 3 3 3 2 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.13 CRK23437.1 - 0.011 15.2 0.0 0.032 13.7 0.0 1.8 1 0 0 1 1 1 0 D-glucuronyl C5-epimerase C-terminus TGT PF01702.18 CRK23438.1 - 6.9e-141 469.4 0.0 8.2e-141 469.2 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Ribosomal_S17e PF00833.18 CRK23439.1 - 3.2e-59 198.2 0.3 3.7e-59 198.0 0.3 1.0 1 0 0 1 1 1 1 Ribosomal S17 RPAP2_Rtr1 PF04181.13 CRK23440.1 - 3.8e-21 75.2 0.0 5.7e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 Rtr1/RPAP2 family Arginosuc_synth PF00764.19 CRK23441.1 - 1.8e-149 498.3 0.0 2.1e-149 498.1 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 CRK23441.1 - 0.011 15.3 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 CRK23441.1 - 0.18 10.6 0.0 0.26 10.0 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase SH3_1 PF00018.28 CRK23442.1 - 1.1e-09 37.7 0.1 2.6e-09 36.5 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CRK23442.1 - 4.2e-09 36.1 0.4 8.5e-09 35.1 0.4 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CRK23442.1 - 3e-05 23.6 0.0 5.8e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain GCP_N_terminal PF17681.1 CRK23444.1 - 4.3e-26 92.3 0.0 6.8e-26 91.6 0.0 1.2 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 CRK23444.1 - 8e-23 81.4 0.0 3.9e-22 79.1 0.0 2.0 1 1 0 1 1 1 1 Gamma tubulin complex component C-terminal CDK2AP PF09806.9 CRK23444.1 - 0.039 14.0 0.2 0.061 13.4 0.2 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Fungal_trans PF04082.18 CRK23445.1 - 1.3e-16 60.5 0.0 2.6e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK23445.1 - 7.6e-07 29.1 7.7 7.6e-07 29.1 7.7 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_33 PF10017.9 CRK23446.1 - 2.3e-61 207.7 0.0 2.6e-61 207.4 0.0 1.0 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent IF-2B PF01008.17 CRK23447.1 - 2.1e-28 99.4 0.0 2.9e-27 95.6 0.0 2.0 2 0 0 2 2 2 2 Initiation factor 2 subunit family DUF1681 PF07933.14 CRK23448.1 - 2.6e-56 189.5 0.0 4.9e-56 188.5 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1681) Ku PF02735.16 CRK23449.1 - 1.7e-45 155.2 0.0 4.6e-45 153.8 0.0 1.7 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 CRK23449.1 - 1.1e-33 116.8 0.0 1.7e-33 116.2 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 CRK23449.1 - 5.1e-27 94.4 3.3 5.1e-27 94.4 3.3 2.2 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm SAP PF02037.27 CRK23449.1 - 2.8e-11 42.9 0.2 6.5e-11 41.7 0.2 1.6 1 0 0 1 1 1 1 SAP domain Ferrochelatase PF00762.19 CRK23450.1 - 2.6e-96 322.4 0.0 3.1e-96 322.2 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase HIT PF01230.23 CRK23451.1 - 9.4e-19 68.0 0.0 2.7e-18 66.5 0.0 1.8 1 0 0 1 1 1 1 HIT domain AAA PF00004.29 CRK23451.1 - 2.4e-10 40.9 0.0 5.4e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CRK23451.1 - 3.6e-06 27.3 0.0 1.2e-05 25.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CRK23451.1 - 4.9e-05 23.3 0.0 0.0001 22.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Rad17 PF03215.15 CRK23451.1 - 5.2e-05 23.3 0.0 0.00015 21.7 0.0 1.7 2 0 0 2 2 2 1 Rad17 P-loop domain RuvB_N PF05496.12 CRK23451.1 - 9.7e-05 22.2 0.0 0.00019 21.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 CRK23451.1 - 0.0015 18.3 0.3 0.0036 17.0 0.3 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CRK23451.1 - 0.0019 18.4 0.0 0.0052 16.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CRK23451.1 - 0.002 18.5 0.4 0.006 17.0 0.0 2.0 2 0 0 2 2 1 1 AAA ATPase domain NTPase_1 PF03266.15 CRK23451.1 - 0.0075 16.2 0.1 0.11 12.4 0.0 2.5 2 0 0 2 2 2 1 NTPase AAA_14 PF13173.6 CRK23451.1 - 0.011 15.8 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 CRK23451.1 - 0.027 14.6 0.0 0.078 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 CRK23451.1 - 0.032 14.8 0.0 0.076 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 CRK23451.1 - 0.051 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_19 PF13245.6 CRK23451.1 - 0.055 13.8 0.1 0.2 12.0 0.1 2.0 1 1 0 1 1 1 0 AAA domain DcpS_C PF11969.8 CRK23451.1 - 0.082 13.4 0.0 0.23 11.9 0.0 1.7 1 0 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding NB-ARC PF00931.22 CRK23451.1 - 0.13 11.5 0.0 0.24 10.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain TsaE PF02367.17 CRK23451.1 - 0.18 11.8 0.0 0.45 10.5 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TFIID_20kDa PF03847.13 CRK23451.1 - 0.31 11.5 1.1 37 4.9 0.1 2.4 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A MFS_1 PF07690.16 CRK23452.1 - 4.8e-21 75.1 35.9 1.3e-15 57.2 14.2 3.7 1 1 3 4 4 4 3 Major Facilitator Superfamily DUF5326 PF17260.2 CRK23452.1 - 0.001 19.2 2.6 0.001 19.2 2.6 3.3 4 0 0 4 4 4 1 Family of unknown function (DUF5326) Semialdhyde_dh PF01118.24 CRK23453.1 - 5e-29 101.2 0.0 1.1e-28 100.1 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 CRK23453.1 - 0.087 12.9 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Pmp3 PF01679.17 CRK23461.1 - 0.16 12.2 2.7 0.2 11.9 2.7 1.1 1 0 0 1 1 1 0 Proteolipid membrane potential modulator Ank_4 PF13637.6 CRK23477.1 - 1.2e-12 48.1 1.6 1.7e-08 34.8 0.2 3.9 3 1 2 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CRK23477.1 - 4.1e-11 43.3 0.1 9.9e-06 26.1 0.1 3.1 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 CRK23477.1 - 2.5e-07 30.8 0.4 0.04 14.4 0.2 3.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 CRK23477.1 - 2.5e-06 27.4 0.2 0.47 11.2 0.1 4.3 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 CRK23477.1 - 1.4e-05 25.3 0.3 0.11 12.8 0.1 3.7 4 0 0 4 4 4 2 Ankyrin repeats (many copies) MFS_1 PF07690.16 CRK23486.1 - 0.0093 14.9 6.6 0.01 14.8 6.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily AceK PF06315.11 CRK23488.1 - 0.0069 14.9 0.1 0.0077 14.8 0.1 1.0 1 0 0 1 1 1 1 Isocitrate dehydrogenase kinase/phosphatase (AceK) UN_NPL4 PF11543.8 CRK23488.1 - 0.15 12.6 0.0 0.2 12.1 0.0 1.2 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Trp_syntA PF00290.20 CRK23488.1 - 0.15 10.9 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Tryptophan synthase alpha chain AIRC PF00731.20 CRK23490.1 - 1.3e-60 203.3 0.3 3.2e-60 202.0 0.3 1.7 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.22 CRK23490.1 - 2.8e-50 170.2 0.0 4.5e-50 169.6 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 CRK23490.1 - 4.9e-12 45.3 0.0 1e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 CRK23490.1 - 3.1e-07 30.2 0.0 7.6e-07 28.9 0.0 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus XdhC_C PF13478.6 CRK23490.1 - 0.0043 17.5 0.0 5.3 7.6 0.0 2.6 2 0 0 2 2 2 2 XdhC Rossmann domain PrpR_N PF06506.11 CRK23490.1 - 0.047 13.3 0.2 0.41 10.2 0.0 2.3 2 0 0 2 2 2 0 Propionate catabolism activator Dus PF01207.17 CRK23491.1 - 1.4e-22 80.2 0.0 3.4e-19 69.1 0.0 2.2 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) Fer2_3 PF13085.6 CRK23492.1 - 4.6e-25 87.7 0.0 7.7e-25 87.0 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 CRK23492.1 - 1.1e-08 35.4 5.8 1.1e-08 35.4 5.8 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 CRK23492.1 - 5e-08 32.9 2.5 5e-08 32.9 2.5 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 CRK23492.1 - 1.1e-07 32.2 7.7 1.1e-07 32.2 7.7 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 CRK23492.1 - 0.00069 20.2 4.6 0.00069 20.2 4.6 2.3 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer2 PF00111.27 CRK23492.1 - 0.0097 15.8 1.4 0.0097 15.8 1.4 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_18 PF13746.6 CRK23492.1 - 0.021 15.0 0.4 0.43 10.8 0.1 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain SF3a60_bindingd PF12108.8 CRK23492.1 - 0.1 12.5 0.4 0.17 11.8 0.4 1.4 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain Fer4_9 PF13187.6 CRK23492.1 - 3.9 7.7 16.2 0.67 10.2 9.3 2.8 2 1 1 3 3 3 0 4Fe-4S dicluster domain SpoIIE PF07228.12 CRK23493.1 - 4.6e-08 33.2 0.1 4.6e-08 33.2 0.1 2.0 3 0 0 3 3 3 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 CRK23493.1 - 1.5e-07 31.3 0.7 1.5e-07 31.3 0.7 2.5 2 1 0 2 2 2 1 Protein phosphatase 2C PP2C PF00481.21 CRK23493.1 - 4e-05 23.4 0.3 0.11 12.1 0.1 2.5 2 0 0 2 2 2 2 Protein phosphatase 2C Orthopox_C10L PF07020.11 CRK23493.1 - 0.065 14.0 4.2 8 7.3 0.3 2.6 2 0 0 2 2 2 0 Orthopoxvirus C10L protein rhaM PF05336.13 CRK23494.1 - 0.023 14.8 0.1 0.046 13.8 0.1 1.4 1 0 0 1 1 1 0 L-rhamnose mutarotase FMO-like PF00743.19 CRK23495.1 - 3.2e-08 32.4 0.1 0.0011 17.5 0.0 2.6 2 1 1 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 CRK23495.1 - 3.9e-06 26.3 0.0 0.04 13.1 0.0 3.2 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CRK23495.1 - 4.1e-06 26.9 0.0 1.2e-05 25.4 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 CRK23495.1 - 0.0031 16.8 0.0 0.069 12.4 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CRK23495.1 - 0.015 14.5 0.0 1.4 8.0 0.0 3.1 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 CRK23495.1 - 0.016 15.2 0.0 2.9 7.9 0.0 3.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding tRNA-synt_1b PF00579.25 CRK23495.1 - 0.18 11.1 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) Methyltransf_16 PF10294.9 CRK23496.1 - 0.059 13.1 0.0 0.13 11.9 0.0 1.5 2 0 0 2 2 2 0 Lysine methyltransferase NAD_binding_8 PF13450.6 CRK23497.1 - 4.9e-10 39.5 0.0 1.3e-09 38.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.19 CRK23497.1 - 4e-08 32.1 0.0 0.00091 17.8 0.0 2.6 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 CRK23497.1 - 1.2e-06 28.0 0.0 0.00015 21.2 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CRK23497.1 - 0.0014 17.8 0.0 2 7.5 0.0 3.8 3 1 1 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 CRK23497.1 - 0.0018 18.3 0.0 0.27 11.2 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 CRK23497.1 - 0.0047 16.2 0.0 0.088 12.0 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase C2 PF00168.30 CRK23498.1 - 4.5e-65 216.4 0.2 2.5e-22 79.1 0.0 4.5 4 0 0 4 4 4 4 C2 domain SMP_LBD PF17047.5 CRK23498.1 - 0.00039 19.9 0.0 0.00071 19.1 0.0 1.4 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain FKBP_C PF00254.28 CRK23498.1 - 0.03 14.6 0.0 0.095 13.0 0.0 1.9 1 0 0 1 1 1 0 FKBP-type peptidyl-prolyl cis-trans isomerase NT-C2 PF10358.9 CRK23498.1 - 0.15 11.8 3.4 0.56 9.9 0.1 3.2 3 1 0 3 3 3 0 N-terminal C2 in EEIG1 and EHBP1 proteins DUF908 PF06012.12 CRK23498.1 - 0.49 9.8 7.3 0.019 14.4 0.9 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) DPBB_1 PF03330.18 CRK23499.1 - 1.6e-08 34.7 0.2 5.4e-08 33.0 0.0 2.0 2 0 0 2 2 2 1 Lytic transglycolase Barwin PF00967.17 CRK23499.1 - 5.2e-07 29.5 0.4 1.1e-06 28.4 0.4 1.5 1 0 0 1 1 1 1 Barwin family Pollen_allerg_1 PF01357.21 CRK23499.1 - 0.0012 18.8 2.2 0.0013 18.7 1.0 1.7 2 0 0 2 2 2 1 Pollen allergen Mo-co_dimer PF03404.16 CRK23499.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Mo-co oxidoreductase dimerisation domain DUF5525 PF17663.1 CRK23499.1 - 6.5 4.7 23.2 9.2 4.2 23.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5525) DPBB_1 PF03330.18 CRK23500.1 - 9.8e-08 32.2 0.4 2.5e-07 30.9 0.0 1.9 2 0 0 2 2 2 1 Lytic transglycolase Barwin PF00967.17 CRK23500.1 - 4e-06 26.7 0.2 7.8e-06 25.7 0.2 1.4 1 0 0 1 1 1 1 Barwin family Pollen_allerg_1 PF01357.21 CRK23500.1 - 0.00015 21.7 0.7 0.00024 21.0 0.7 1.3 1 0 0 1 1 1 1 Pollen allergen Cerato-platanin PF07249.12 CRK23500.1 - 0.034 14.3 0.1 0.056 13.6 0.1 1.4 1 0 0 1 1 1 0 Cerato-platanin Mo-co_dimer PF03404.16 CRK23500.1 - 0.093 12.7 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Mo-co oxidoreductase dimerisation domain BNR PF02012.20 CRK23500.1 - 0.13 12.3 0.8 0.29 11.3 0.8 1.6 1 0 0 1 1 1 0 BNR/Asp-box repeat NICE-1 PF15845.5 CRK23500.1 - 0.86 10.4 4.0 2.1 9.2 4.0 1.7 1 0 0 1 1 1 0 Cysteine-rich C-terminal 1 family EH_Signature PF15611.6 CRK23501.1 - 0.046 13.1 0.1 0.076 12.4 0.1 1.3 1 0 0 1 1 1 0 EH_Signature domain FYVE PF01363.21 CRK23502.1 - 4.3e-21 74.8 1.8 4.3e-21 74.8 1.8 3.0 3 0 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.6 CRK23502.1 - 3.1e-07 30.6 4.6 3.1e-07 30.6 4.6 4.1 4 0 0 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.6 CRK23502.1 - 0.0002 21.1 3.7 0.0002 21.1 3.7 3.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CRK23502.1 - 0.0011 18.6 4.5 0.0011 18.6 4.5 3.0 3 0 0 3 3 3 1 RING-like zinc finger FYVE_2 PF02318.16 CRK23502.1 - 0.011 16.0 1.1 0.011 16.0 1.1 2.4 2 0 0 2 2 2 0 FYVE-type zinc finger zf-RING-like PF08746.11 CRK23502.1 - 0.013 15.8 3.3 0.013 15.8 3.3 2.5 2 0 0 2 2 1 0 RING-like domain DZR PF12773.7 CRK23502.1 - 0.069 13.2 8.3 1.2 9.2 4.7 2.9 2 0 0 2 2 2 0 Double zinc ribbon zf-piccolo PF05715.13 CRK23502.1 - 0.15 12.2 14.0 0.064 13.4 4.9 2.9 3 0 0 3 3 2 0 Piccolo Zn-finger Rad50_zn_hook PF04423.14 CRK23502.1 - 0.24 11.3 3.7 0.18 11.7 0.8 2.2 2 0 0 2 2 2 0 Rad50 zinc hook motif zinc_ribbon_2 PF13240.6 CRK23502.1 - 3.8 7.3 8.0 8.6 6.2 0.1 3.5 3 0 0 3 3 3 0 zinc-ribbon domain zf-RING_UBOX PF13445.6 CRK23502.1 - 5.3 7.1 26.7 0.08 13.0 4.7 3.7 3 0 0 3 3 3 0 RING-type zinc-finger AAA PF00004.29 CRK23503.1 - 2.9e-40 137.8 0.0 5.3e-40 136.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CRK23503.1 - 2.2e-07 30.6 0.0 5.3e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 CRK23503.1 - 7.5e-05 22.8 0.1 0.00062 19.8 0.0 2.5 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CRK23503.1 - 0.00013 22.3 0.0 0.0055 17.0 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.14 CRK23503.1 - 0.00055 20.1 0.0 0.0016 18.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 CRK23503.1 - 0.00067 20.1 0.1 0.014 15.8 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 CRK23503.1 - 0.0015 17.7 0.0 0.0027 16.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 CRK23503.1 - 0.0091 15.8 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 CRK23503.1 - 0.019 15.2 0.0 0.063 13.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 CRK23503.1 - 0.028 14.1 0.1 0.59 9.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CRK23503.1 - 0.033 13.7 0.0 0.095 12.2 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 CRK23503.1 - 0.049 13.8 0.0 0.095 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CRK23503.1 - 0.055 13.9 0.0 0.15 12.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.11 CRK23503.1 - 0.079 12.8 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 CRK23503.1 - 0.097 12.7 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CRK23503.1 - 0.1 12.3 0.0 0.28 10.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 CRK23503.1 - 0.16 11.3 0.0 0.36 10.2 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Cytochrom_C1 PF02167.15 CRK23504.1 - 3.5e-90 301.5 0.0 5.7e-90 300.8 0.0 1.3 1 0 0 1 1 1 1 Cytochrome C1 family JUPITER PF17054.5 CRK23504.1 - 0.0029 17.1 0.1 0.0044 16.5 0.1 1.2 1 0 0 1 1 1 1 Microtubule-Associated protein Jupiter Cytochrome_CBB3 PF13442.6 CRK23504.1 - 0.0033 17.7 3.1 0.045 14.1 0.0 2.8 2 0 0 2 2 2 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 CRK23504.1 - 2.2 9.5 0.0 2.2 9.5 0.0 3.6 3 1 0 3 3 3 0 Cytochrome c eRF1_1 PF03463.15 CRK23507.1 - 3.2e-34 117.7 0.0 6.1e-34 116.8 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 1 Aldo_ket_red PF00248.21 CRK23507.1 - 2.8e-21 76.0 0.0 4.2e-21 75.4 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family eRF1_2 PF03464.15 CRK23507.1 - 2.6e-20 73.1 0.1 5.8e-20 72.0 0.1 1.6 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 CRK23507.1 - 2.1e-17 63.7 0.0 4.1e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 RAI16-like PF10257.9 CRK23508.1 - 1.5e-11 43.8 0.0 2e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein DUF2170 PF09938.9 CRK23508.1 - 0.095 12.4 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2170) Ribosomal_L1 PF00687.21 CRK23532.1 - 1.8e-30 106.2 0.8 2.1e-30 106.0 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Pectinesterase PF01095.19 CRK23533.1 - 8.3e-11 41.1 1.3 9.2e-11 41.0 1.3 1.0 1 0 0 1 1 1 1 Pectinesterase RRM_1 PF00076.22 CRK23536.1 - 6.7e-13 48.3 0.0 1.1e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HNH_2 PF13391.6 CRK23536.1 - 0.11 12.6 0.9 0.38 10.9 0.9 1.9 1 1 0 1 1 1 0 HNH endonuclease RRM_7 PF16367.5 CRK23536.1 - 0.2 11.8 0.0 0.3 11.2 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif Ras PF00071.22 CRK23537.1 - 1.8e-23 83.0 0.0 2.1e-23 82.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CRK23537.1 - 7.9e-11 42.2 0.0 1e-10 41.9 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ApbA_C PF08546.11 CRK23538.1 - 1.3e-20 73.9 0.0 3.6e-20 72.4 0.0 1.7 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 CRK23538.1 - 2e-09 37.3 0.0 3.4e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NUC153 PF08159.12 CRK23538.1 - 0.13 12.1 0.0 0.48 10.3 0.0 1.9 2 0 0 2 2 2 0 NUC153 domain Sas10_Utp3 PF04000.15 CRK23540.1 - 2e-15 57.2 0.6 2e-15 57.2 0.6 2.1 2 0 0 2 2 2 1 Sas10/Utp3/C1D family DUF3619 PF12279.8 CRK23540.1 - 0.025 14.9 1.2 0.054 13.8 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) LcrG PF07216.12 CRK23540.1 - 0.12 12.3 3.3 1.1 9.2 0.1 2.3 1 1 1 2 2 2 0 LcrG protein H_PPase PF03030.16 CRK23540.1 - 0.19 10.3 0.0 0.23 10.1 0.0 1.1 1 0 0 1 1 1 0 Inorganic H+ pyrophosphatase DPM3 PF08285.11 CRK23540.1 - 0.2 11.9 0.0 0.2 11.9 0.0 1.9 3 0 0 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Syntaxin-6_N PF09177.11 CRK23540.1 - 0.29 11.7 3.1 1.3 9.7 1.3 2.2 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Tti2 PF10521.9 CRK23540.1 - 0.56 9.7 3.7 0.41 10.1 2.3 1.5 2 0 0 2 2 2 0 Tti2 family UBX PF00789.20 CRK23541.1 - 7.5e-12 45.3 0.0 1.4e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 UBX domain G0-G1_switch_2 PF15103.6 CRK23541.1 - 0.00079 19.8 5.9 0.0066 16.9 0.0 2.6 2 0 0 2 2 2 1 G0/G1 switch protein 2 Thioredoxin_7 PF13899.6 CRK23541.1 - 0.06 13.5 0.0 0.2 11.9 0.0 1.9 1 0 0 1 1 1 0 Thioredoxin-like FAM53 PF15242.6 CRK23541.1 - 1.1 9.0 15.1 2.1 8.1 15.1 1.4 1 0 0 1 1 1 0 Family of FAM53 MSP1_C PF07462.11 CRK23541.1 - 1.2 7.7 4.7 1.9 7.1 4.7 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus PBP_N PF17093.5 CRK23541.1 - 2.7 8.3 7.1 6.5 7.0 4.6 2.5 2 0 0 2 2 2 0 Penicillin-binding protein N-terminus SURF1 PF02104.15 CRK23542.1 - 8.5e-47 159.6 0.1 1.1e-46 159.3 0.1 1.1 1 0 0 1 1 1 1 SURF1 family CENP-T_C PF15511.6 CRK23543.1 - 5.7e-41 139.0 0.0 9.1e-41 138.4 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 CRK23543.1 - 1.9e-08 34.6 0.0 3.3e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 CENP-S protein Histone PF00125.24 CRK23543.1 - 1.9e-08 34.8 0.0 1.9e-08 34.8 0.0 2.6 3 1 0 3 3 3 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CRK23543.1 - 0.0012 19.1 0.0 0.0027 18.0 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 CRK23543.1 - 0.093 12.8 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Coq4 PF05019.13 CRK23544.1 - 3.9e-95 317.4 0.0 4.6e-95 317.1 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 SET PF00856.28 CRK23545.1 - 9.2e-12 45.7 0.0 1.6e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 SET domain HHH PF00633.23 CRK23545.1 - 0.0062 16.4 0.2 0.021 14.7 0.1 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif SecE PF00584.20 CRK23547.1 - 5.8e-11 42.2 0.0 7.6e-11 41.8 0.0 1.3 1 1 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex WD40 PF00400.32 CRK23548.1 - 4.7e-21 74.7 19.2 5.8e-05 23.8 1.3 7.5 7 0 0 7 7 7 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 CRK23548.1 - 0.00015 20.5 4.9 0.0059 15.2 0.2 3.4 4 0 0 4 4 4 2 Cytochrome D1 heme domain ANAPC4_WD40 PF12894.7 CRK23548.1 - 0.00027 21.2 0.0 0.11 12.8 0.0 3.8 4 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 CRK23548.1 - 0.02 14.8 0.0 0.13 12.2 0.0 2.4 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat SDA1 PF05285.12 CRK23548.1 - 0.069 12.6 12.4 0.092 12.2 12.4 1.2 1 0 0 1 1 1 0 SDA1 VIGSSK PF14773.6 CRK23548.1 - 0.14 12.3 0.0 0.33 11.1 0.0 1.6 1 0 0 1 1 1 0 Helicase-associated putative binding domain, C-terminal TRAP_alpha PF03896.16 CRK23548.1 - 8.2 5.5 6.0 14 4.8 6.0 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Sugar_tr PF00083.24 CRK23549.1 - 3.4e-53 181.1 20.0 2.3e-49 168.5 11.2 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CRK23549.1 - 0.023 13.6 36.9 0.072 12.0 15.4 2.8 1 1 1 2 2 2 0 Major Facilitator Superfamily Phage_holin_2_4 PF16082.5 CRK23549.1 - 4.9 6.9 7.1 9 6.1 0.0 3.1 3 0 0 3 3 3 0 Bacteriophage holin family, superfamily II-like UPF0016 PF01169.19 CRK23550.1 - 2.6e-40 136.6 24.5 6.1e-20 71.3 9.7 2.3 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 MFS_1 PF07690.16 CRK23551.1 - 3.1e-39 134.9 30.3 5.7e-30 104.4 9.5 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK23551.1 - 3.6e-16 59.1 4.0 3.6e-16 59.1 4.0 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 CRK23551.1 - 2.2e-05 23.1 3.2 3.4e-05 22.5 3.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PRT_C PF08372.10 CRK23551.1 - 0.29 10.9 3.8 0.16 11.7 0.8 2.0 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal Thioredoxin PF00085.20 CRK23552.1 - 6e-06 26.2 0.0 9.4e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 CRK23552.1 - 0.0038 16.6 0.0 0.0046 16.3 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 CRK23552.1 - 0.017 15.3 0.0 0.03 14.5 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like Redoxin PF08534.10 CRK23552.1 - 0.05 13.3 0.0 0.063 13.0 0.0 1.2 1 0 0 1 1 1 0 Redoxin rhaM PF05336.13 CRK23553.1 - 1.2e-37 128.2 0.7 1.5e-37 128.0 0.7 1.1 1 0 0 1 1 1 1 L-rhamnose mutarotase ELP6 PF09807.9 CRK23554.1 - 1.5e-09 37.7 0.0 3.1e-09 36.6 0.0 1.4 1 1 0 1 1 1 1 Elongation complex protein 6 Ribosomal_L37e PF01907.19 CRK23555.1 - 3.5e-12 46.3 3.8 6.2e-12 45.5 3.8 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e Spc7 PF08317.11 CRK23555.1 - 0.00082 18.3 18.9 0.011 14.6 2.3 2.9 3 0 0 3 3 3 2 Spc7 kinetochore protein BLOC1_2 PF10046.9 CRK23555.1 - 0.0096 16.2 2.6 0.0096 16.2 2.6 2.7 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Rootletin PF15035.6 CRK23555.1 - 0.063 13.3 12.4 0.76 9.8 5.8 2.5 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Baculo_PEP_C PF04513.12 CRK23555.1 - 0.069 13.2 0.7 0.35 10.9 0.1 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prefoldin PF02996.17 CRK23555.1 - 0.069 13.1 6.3 0.076 12.9 0.2 3.1 1 1 2 3 3 3 0 Prefoldin subunit DHR10 PF18595.1 CRK23555.1 - 0.1 12.6 21.3 0.29 11.2 18.2 3.1 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain FlxA PF14282.6 CRK23555.1 - 0.12 12.4 15.2 0.75 9.8 3.1 3.0 2 1 0 2 2 2 0 FlxA-like protein EzrA PF06160.12 CRK23555.1 - 0.15 10.2 9.4 0.23 9.6 9.4 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Filament PF00038.21 CRK23555.1 - 0.18 11.4 14.3 1.5 8.3 6.4 2.3 1 1 0 2 2 2 0 Intermediate filament protein Atg14 PF10186.9 CRK23555.1 - 0.18 10.9 20.8 0.088 11.9 1.6 2.2 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Arm-DNA-bind_5 PF17293.2 CRK23555.1 - 0.6 10.6 4.8 21 5.6 0.0 2.7 2 0 0 2 2 2 0 Arm DNA-binding domain LCD1 PF09798.9 CRK23555.1 - 0.6 8.6 7.7 0.98 7.9 7.7 1.3 1 0 0 1 1 1 0 DNA damage checkpoint protein Fez1 PF06818.15 CRK23555.1 - 0.75 10.2 20.3 1.1 9.7 10.6 2.4 1 1 1 2 2 2 0 Fez1 DUF1664 PF07889.12 CRK23555.1 - 0.89 9.6 5.9 12 6.0 0.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) PAXX PF15384.6 CRK23555.1 - 0.96 9.1 7.9 0.55 9.9 0.5 2.5 1 1 0 2 2 2 0 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 UPF0242 PF06785.11 CRK23555.1 - 1.3 9.1 21.1 1.2 9.2 12.4 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Laminin_II PF06009.12 CRK23555.1 - 1.9 8.5 13.5 6 6.9 3.2 3.3 2 1 0 3 3 3 0 Laminin Domain II OmpH PF03938.14 CRK23555.1 - 2.1 8.7 20.5 6.8 7.0 4.1 2.5 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Allexi_40kDa PF05549.11 CRK23555.1 - 2.5 7.5 9.2 3.7 7.0 0.2 3.0 2 1 0 3 3 3 0 Allexivirus 40kDa protein GAS PF13851.6 CRK23555.1 - 2.6 7.4 19.4 1.9 7.8 3.3 2.7 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding Spc24 PF08286.11 CRK23555.1 - 2.6 8.3 12.9 1.1 9.6 2.6 3.3 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 LMBR1 PF04791.16 CRK23555.1 - 2.9 6.7 4.1 3.6 6.4 4.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Phage_GP20 PF06810.11 CRK23555.1 - 3.7 7.3 22.5 1.7 8.5 0.3 3.6 3 1 1 4 4 4 0 Phage minor structural protein GP20 ABC_tran_CTD PF16326.5 CRK23555.1 - 3.9 7.8 24.9 27 5.1 7.2 3.9 2 1 1 3 3 3 0 ABC transporter C-terminal domain HAUS5 PF14817.6 CRK23555.1 - 4.1 6.0 16.0 13 4.4 16.1 1.7 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 5 DivIC PF04977.15 CRK23555.1 - 4.6 7.1 21.0 1.5 8.6 4.8 3.8 2 2 1 3 3 3 0 Septum formation initiator TolA_bind_tri PF16331.5 CRK23555.1 - 4.7 7.4 16.3 6.5 6.9 2.6 3.9 3 1 1 4 4 3 0 TolA binding protein trimerisation DUF4407 PF14362.6 CRK23555.1 - 4.8 6.4 15.7 16 4.7 15.3 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF16 PF01519.16 CRK23555.1 - 5 7.7 10.7 3.6 8.1 0.8 2.7 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF2730 PF10805.8 CRK23555.1 - 5.3 7.2 9.8 7.4 6.7 0.4 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) FapA PF03961.13 CRK23555.1 - 5.5 5.5 10.9 22 3.5 10.7 1.8 1 1 2 3 3 3 0 Flagellar Assembly Protein A YlqD PF11068.8 CRK23555.1 - 6.3 7.2 17.0 9.4 6.6 3.1 2.8 2 1 0 2 2 2 0 YlqD protein V_ATPase_I PF01496.19 CRK23555.1 - 6.5 4.5 5.0 7.3 4.4 4.2 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family BRE1 PF08647.11 CRK23555.1 - 7.9 6.6 15.0 0.26 11.4 3.2 2.9 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase PRKG1_interact PF15898.5 CRK23555.1 - 8.4 7.4 18.9 12 6.9 9.1 2.8 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain YflT PF11181.8 CRK23557.1 - 0.27 11.8 1.8 0.4 11.2 0.4 2.0 2 0 0 2 2 2 0 Heat induced stress protein YflT zf-RING_2 PF13639.6 CRK23558.1 - 1.1e-12 48.1 5.3 1.9e-12 47.3 5.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CRK23558.1 - 2.9e-10 39.8 4.5 5.7e-10 38.9 4.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CRK23558.1 - 2.7e-09 37.2 2.7 5.2e-09 36.3 2.7 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CRK23558.1 - 9.6e-09 35.0 3.9 1.8e-08 34.1 3.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CRK23558.1 - 1e-08 34.7 2.5 1e-08 34.7 2.5 1.9 2 0 0 2 2 2 1 RING-like zinc finger PA PF02225.22 CRK23558.1 - 1.4e-08 34.7 0.0 2.9e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 PA domain zf-RING_5 PF14634.6 CRK23558.1 - 3.8e-07 29.9 3.0 7.5e-07 29.0 3.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CRK23558.1 - 1e-06 28.6 3.7 2.6e-06 27.4 0.4 2.9 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CRK23558.1 - 5e-06 26.3 2.9 8.3e-06 25.6 2.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CRK23558.1 - 0.0013 18.8 1.0 0.0025 17.8 1.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 CRK23558.1 - 0.0031 17.4 3.1 0.0081 16.0 3.1 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 CRK23558.1 - 0.024 14.3 3.1 0.048 13.3 3.1 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 CRK23558.1 - 0.087 13.0 5.7 0.1 12.7 3.5 2.3 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 CRK23558.1 - 0.089 13.0 2.7 0.24 11.6 2.7 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 CRK23558.1 - 0.11 12.3 3.0 0.23 11.3 3.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.29 CRK23558.1 - 0.15 12.0 3.0 0.27 11.2 3.0 1.4 1 0 0 1 1 1 0 PHD-finger RINGv PF12906.7 CRK23558.1 - 0.22 11.7 4.2 0.45 10.7 4.2 1.6 1 0 0 1 1 1 0 RING-variant domain zf-Nse PF11789.8 CRK23558.1 - 0.46 10.3 2.8 0.99 9.3 2.8 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING-like PF08746.11 CRK23558.1 - 0.72 10.2 3.5 1.4 9.3 3.5 1.5 1 0 0 1 1 1 0 RING-like domain DUF4083 PF13314.6 CRK23558.1 - 4.9 7.2 6.1 11 6.0 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) LANC_like PF05147.13 CRK23559.1 - 7.5e-25 87.3 0.0 6.9e-24 84.1 0.0 2.0 1 1 1 2 2 2 2 Lanthionine synthetase C-like protein EI24 PF07264.11 CRK23560.1 - 7.3e-14 52.4 3.5 2e-13 51.0 3.5 1.8 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Glyco_hydro_31 PF01055.26 CRK23560.1 - 2.1e-13 50.3 0.0 3.7e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 RecQ_Zn_bind PF16124.5 CRK23562.1 - 7.9e-20 71.4 4.7 1.3e-19 70.7 4.7 1.4 1 0 0 1 1 1 1 RecQ zinc-binding Helicase_C PF00271.31 CRK23562.1 - 3.2e-06 27.5 0.0 8.2e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TRAPPC9-Trs120 PF08626.11 CRK23563.1 - 9.7e-36 122.6 0.0 1.1e-35 122.4 0.0 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Svf1 PF08622.10 CRK23566.1 - 5.9e-22 78.5 0.0 7.1e-22 78.2 0.0 1.1 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain Svf1_C PF17187.4 CRK23566.1 - 3.6e-13 49.7 0.4 4.5e-13 49.4 0.4 1.1 1 0 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain APG6_N PF17675.1 CRK23581.1 - 0.0072 16.9 16.6 0.0094 16.5 16.6 1.2 1 0 0 1 1 1 1 Apg6 coiled-coil region PCRF PF03462.18 CRK23581.1 - 0.014 15.2 6.6 0.078 12.8 6.6 1.9 1 1 0 1 1 1 0 PCRF domain MCC-bdg_PDZ PF10506.9 CRK23581.1 - 0.029 14.4 2.4 0.046 13.7 1.1 2.0 1 1 1 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome TMF_TATA_bd PF12325.8 CRK23581.1 - 0.09 13.0 14.0 1.2 9.4 4.5 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Podovirus_Gp16 PF05894.12 CRK23581.1 - 0.11 11.9 0.2 0.13 11.8 0.2 1.1 1 0 0 1 1 1 0 Podovirus DNA encapsidation protein (Gp16) GAS PF13851.6 CRK23581.1 - 0.22 10.8 15.7 0.76 9.1 15.9 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF2570 PF10828.8 CRK23581.1 - 0.29 11.0 9.6 0.2 11.5 7.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) DUF724 PF05266.14 CRK23581.1 - 0.37 10.6 9.4 0.62 9.9 9.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF724) DUF5345 PF17280.2 CRK23581.1 - 0.81 9.7 6.3 0.13 12.3 1.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5345) Cnn_1N PF07989.11 CRK23581.1 - 0.89 9.8 13.9 0.27 11.4 1.7 2.3 1 1 0 2 2 2 0 Centrosomin N-terminal motif 1 Jnk-SapK_ap_N PF09744.9 CRK23581.1 - 1.1 9.5 17.4 0.16 12.2 5.8 2.0 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 HIP1_clath_bdg PF16515.5 CRK23581.1 - 1.1 10.0 14.3 1.4 9.6 3.2 2.2 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ATG16 PF08614.11 CRK23581.1 - 1.2 9.3 17.6 0.045 14.0 5.3 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DivIVA PF05103.13 CRK23581.1 - 1.6 8.8 12.7 1.3 9.1 6.2 2.2 1 1 1 2 2 2 0 DivIVA protein DUF3450 PF11932.8 CRK23581.1 - 2.6 7.3 12.9 0.1 11.9 3.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) TMPIT PF07851.13 CRK23581.1 - 3.2 6.9 6.3 3.8 6.7 6.3 1.2 1 0 0 1 1 1 0 TMPIT-like protein WW PF00397.26 CRK23600.1 - 0.014 15.5 4.0 0.05 13.7 4.0 2.0 1 1 0 1 1 1 0 WW domain SRI PF08236.11 CRK23606.1 - 1e-15 57.7 6.9 1.2e-15 57.4 6.9 1.1 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain TRAPPC-Trs85 PF12739.7 CRK23606.1 - 0.026 13.5 0.1 0.029 13.4 0.1 1.0 1 0 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit GTP-bdg_N PF13167.6 CRK23606.1 - 0.042 14.5 0.1 0.052 14.2 0.1 1.1 1 0 0 1 1 1 0 GTP-binding GTPase N-terminal BEN PF10523.9 CRK23606.1 - 0.047 13.9 1.0 0.11 12.7 0.8 1.7 1 1 1 2 2 2 0 BEN domain Iron_traffic PF04362.14 CRK23606.1 - 0.058 13.1 0.0 0.062 13.0 0.0 1.1 1 0 0 1 1 1 0 Bacterial Fe(2+) trafficking CdiI_2 PF18593.1 CRK23606.1 - 0.12 13.0 0.0 0.19 12.4 0.0 1.4 1 1 0 1 1 1 0 CdiI immunity protein PRCC PF10253.9 CRK23610.1 - 0.024 15.4 3.3 0.034 15.0 3.3 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Med13_C PF06333.12 CRK23610.1 - 0.84 8.8 12.5 1.2 8.3 12.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Tom22 PF04281.13 CRK23611.1 - 3.6e-41 140.2 0.0 6e-41 139.5 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 A_deaminase PF00962.22 CRK23611.1 - 4.3e-21 75.6 0.0 7e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase TatD_DNase PF01026.21 CRK23611.1 - 0.056 12.8 0.0 0.091 12.1 0.0 1.3 1 0 0 1 1 1 0 TatD related DNase MFS_1 PF07690.16 CRK23612.1 - 7.7e-23 81.0 47.1 7.4e-18 64.6 25.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ArsP_1 PF03773.13 CRK23613.1 - 0.01 15.0 0.8 0.015 14.5 0.0 1.6 2 0 0 2 2 2 0 Predicted permease zf-LITAF-like PF10601.9 CRK23613.1 - 0.05 13.9 0.2 0.05 13.9 0.2 1.7 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain Mucin PF01456.17 CRK23613.1 - 4 7.4 9.5 1.2 9.1 0.5 2.4 2 1 0 2 2 2 0 Mucin-like glycoprotein MFS_1 PF07690.16 CRK23615.1 - 5.2e-17 61.8 13.2 5e-09 35.5 0.9 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily SpoVAB PF13782.6 CRK23615.1 - 0.007 16.6 0.5 0.23 11.8 0.4 2.1 1 1 1 2 2 2 1 Stage V sporulation protein AB Peptidase_S8 PF00082.22 CRK23617.1 - 1.5e-36 126.2 0.0 3.4e-36 125.1 0.0 1.7 1 1 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 CRK23617.1 - 2.9e-11 44.1 0.1 2.9e-11 44.1 0.1 2.3 2 0 0 2 2 2 1 Fn3-like domain Lip_prot_lig_C PF10437.9 CRK23617.1 - 0.00011 22.1 0.1 1.1 9.3 0.0 2.9 3 0 0 3 3 3 2 Bacterial lipoate protein ligase C-terminus NapD PF03927.13 CRK23617.1 - 0.17 12.0 0.1 38 4.4 0.0 2.7 2 0 0 2 2 2 0 NapD protein DUF3405 PF11885.8 CRK23618.1 - 1.3e-141 472.7 0.2 1.8e-141 472.3 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) AMP-binding PF00501.28 CRK23619.1 - 5.1e-45 153.8 0.0 8.8e-45 153.0 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 CRK23619.1 - 4.5e-15 55.8 0.0 5.4e-14 52.3 0.0 2.4 2 0 0 2 2 2 1 Phosphopantetheine attachment site Hexapep PF00132.24 CRK23619.1 - 0.0013 18.4 6.8 0.4 10.5 0.0 5.2 6 0 0 6 6 6 2 Bacterial transferase hexapeptide (six repeats) AMP-binding_C PF13193.6 CRK23619.1 - 0.016 16.2 0.0 1.4 9.9 0.0 2.7 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain Lyase_1 PF00206.20 CRK23621.1 - 8.4e-35 120.6 0.0 1.4e-34 119.9 0.0 1.4 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 CRK23621.1 - 2.4e-19 69.8 0.9 1.5e-12 48.1 0.2 2.8 1 1 1 2 2 2 2 Argininosuccinate lyase C-terminal MFS_1 PF07690.16 CRK23622.1 - 7.2e-21 74.5 68.1 1.9e-17 63.2 35.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5423 PF17461.2 CRK23622.1 - 9.1 5.0 6.1 14 4.4 6.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5423) Fungal_trans PF04082.18 CRK23625.1 - 3.2e-22 78.8 0.3 5.1e-22 78.2 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 CRK23625.1 - 1.2e-08 35.0 13.4 0.00019 21.7 2.0 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CRK23625.1 - 1.2e-06 28.6 12.9 2.3e-06 27.8 7.1 2.8 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 CRK23625.1 - 0.00046 20.8 13.0 0.037 14.9 2.1 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger C1_4 PF07975.12 CRK23625.1 - 0.35 11.1 2.1 0.9 9.8 2.1 1.7 1 0 0 1 1 1 0 TFIIH C1-like domain zf-C2H2_jaz PF12171.8 CRK23625.1 - 0.77 10.1 3.7 0.43 10.9 0.4 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CRK23625.1 - 2.3 8.7 5.2 0.63 10.5 1.1 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type NACHT PF05729.12 CRK23626.1 - 8.3e-10 38.8 0.0 1.6e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 CRK23626.1 - 0.00013 22.3 0.0 0.00035 20.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CRK23626.1 - 0.00016 22.1 1.5 0.00045 20.6 0.0 2.4 3 1 1 4 4 4 1 AAA ATPase domain RNA_helicase PF00910.22 CRK23626.1 - 0.00059 20.2 0.1 0.17 12.3 0.0 2.6 2 0 0 2 2 2 1 RNA helicase NB-ARC PF00931.22 CRK23626.1 - 0.00065 19.0 0.0 0.0027 16.9 0.0 2.0 1 1 0 1 1 1 1 NB-ARC domain AAA_25 PF13481.6 CRK23626.1 - 0.0024 17.5 0.0 0.0095 15.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 CRK23626.1 - 0.0039 17.6 0.0 0.012 16.0 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.14 CRK23626.1 - 0.0082 15.4 0.0 0.068 12.4 0.0 2.1 1 1 0 2 2 2 1 KAP family P-loop domain AAA_24 PF13479.6 CRK23626.1 - 0.037 13.7 0.0 0.086 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Metallophos PF00149.28 CRK23629.1 - 0.14 12.7 0.0 0.21 12.1 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase Forkhead PF00250.18 CRK23630.1 - 8.8e-05 22.7 0.0 0.00014 22.1 0.0 1.3 1 0 0 1 1 1 1 Forkhead domain TPP_enzyme_N PF02776.18 CRK23633.1 - 4.2e-15 55.8 0.0 5.2e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain AMP-binding PF00501.28 CRK23646.1 - 1.4e-16 60.1 0.0 1.6e-16 60.0 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Ino80_Iec3 PF14612.6 CRK23647.1 - 1.6e-12 48.7 4.1 2.1e-12 48.2 4.1 1.2 1 0 0 1 1 1 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling MFS_1 PF07690.16 CRK23647.1 - 2.5e-05 23.4 8.8 2.8e-05 23.2 8.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 CRK23647.1 - 0.0052 15.4 1.0 0.0057 15.3 1.0 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein Aa_trans PF01490.18 CRK23648.1 - 1.5e-05 23.9 4.0 1.6e-05 23.8 4.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein VIT1 PF01988.19 CRK23648.1 - 0.37 10.6 3.3 0.51 10.2 3.3 1.3 1 1 0 1 1 1 0 VIT family APH PF01636.23 CRK23650.1 - 1.7e-11 44.6 0.0 2.4e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 CRK23650.1 - 0.0015 18.1 0.1 0.029 14.0 0.0 2.3 2 1 0 2 2 2 1 RIO1 family Choline_kinase PF01633.20 CRK23650.1 - 0.025 14.1 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase SF3b10 PF07189.11 CRK23651.1 - 8.9e-38 128.3 0.0 9.9e-38 128.1 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) MAGE PF01454.19 CRK23652.1 - 1.1e-59 201.7 0.0 1.6e-59 201.2 0.0 1.2 1 0 0 1 1 1 1 MAGE family SLS PF14611.6 CRK23653.1 - 1e-25 90.9 0.5 2.5e-25 89.6 0.0 1.9 2 0 0 2 2 2 1 Mitochondrial inner-membrane-bound regulator Imm74 PF15603.6 CRK23653.1 - 0.18 12.0 0.0 0.49 10.6 0.0 1.7 1 0 0 1 1 1 0 Immunity protein 74 GTP_EFTU PF00009.27 CRK23654.1 - 3.1e-54 183.5 1.7 1.1e-53 181.7 1.7 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CRK23654.1 - 4.2e-41 139.8 0.1 1.4e-40 138.0 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CRK23654.1 - 4.4e-15 55.8 2.2 6.7e-15 55.2 0.8 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CRK23654.1 - 0.00055 20.0 0.2 0.015 15.4 0.1 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF5484 PF17583.2 CRK23654.1 - 0.014 15.1 4.3 1.1 8.9 0.9 2.5 1 1 1 2 2 2 0 Family of unknown function (DUF5484) TCTP PF00838.17 CRK23654.1 - 0.05 13.9 0.2 0.1 12.9 0.2 1.5 1 0 0 1 1 1 0 Translationally controlled tumour protein GTP_EFTU_D4 PF14578.6 CRK23654.1 - 0.09 12.7 0.3 0.26 11.2 0.3 1.8 1 0 0 1 1 1 0 Elongation factor Tu domain 4 Adaptin_N PF01602.20 CRK23655.1 - 1.2e-111 373.8 2.0 1.6e-111 373.5 2.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 CRK23655.1 - 1.6e-55 187.4 5.7 3.7e-55 186.2 5.7 1.7 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 CRK23655.1 - 1.3e-36 125.2 0.5 3.6e-36 123.8 0.1 2.0 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 CRK23655.1 - 3.6e-17 62.5 4.5 2.7e-12 46.9 0.1 5.2 3 1 2 5 5 5 1 HEAT repeats Cnd1 PF12717.7 CRK23655.1 - 6.1e-07 29.6 12.3 0.027 14.5 0.1 5.1 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 CRK23655.1 - 0.0012 19.3 0.0 1.2 10.0 0.0 4.2 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat CLASP_N PF12348.8 CRK23655.1 - 0.0038 16.8 8.9 0.0092 15.6 0.2 3.9 4 0 0 4 4 4 1 CLASP N terminal Coatomer_b_Cpla PF14806.6 CRK23655.1 - 0.019 14.9 0.0 0.11 12.5 0.0 2.2 2 0 0 2 2 2 0 Coatomer beta subunit appendage platform DUF5010 PF16402.5 CRK23655.1 - 0.041 12.7 0.0 0.13 11.1 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5010) HEAT PF02985.22 CRK23655.1 - 0.1 12.9 8.8 1.7 9.1 0.2 5.4 5 0 0 5 5 5 0 HEAT repeat RTP1_C1 PF10363.9 CRK23655.1 - 0.12 12.6 1.6 3.1 8.0 0.1 3.5 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 CDP-OH_P_transf PF01066.21 CRK23656.1 - 8.8e-17 61.6 0.1 8.8e-17 61.6 0.1 3.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase bZIP_1 PF00170.21 CRK23657.1 - 8.9e-09 35.3 15.0 1.5e-08 34.6 15.0 1.4 1 0 0 1 1 1 1 bZIP transcription factor PAP1 PF08601.10 CRK23657.1 - 2e-05 24.5 0.0 2e-05 24.5 0.0 3.0 1 1 1 2 2 2 1 Transcription factor PAP1 bZIP_Maf PF03131.17 CRK23657.1 - 0.00075 20.0 9.9 0.00075 20.0 9.9 2.4 2 0 0 2 2 2 1 bZIP Maf transcription factor V_ATPase_I PF01496.19 CRK23657.1 - 0.0018 16.3 0.7 0.0018 16.3 0.7 2.1 2 0 0 2 2 2 1 V-type ATPase 116kDa subunit family SHE3 PF17078.5 CRK23657.1 - 0.011 15.4 6.8 0.011 15.4 6.8 1.8 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 YabA PF06156.13 CRK23657.1 - 0.043 14.4 0.3 0.043 14.4 0.3 2.3 2 0 0 2 2 2 0 Initiation control protein YabA bZIP_2 PF07716.15 CRK23657.1 - 0.21 11.7 18.8 0.47 10.6 17.7 2.1 1 1 1 2 2 2 0 Basic region leucine zipper FlaC_arch PF05377.11 CRK23657.1 - 0.24 11.8 1.9 0.46 10.9 1.9 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF812 PF05667.11 CRK23657.1 - 0.29 10.0 12.0 0.46 9.3 12.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) ADIP PF11559.8 CRK23657.1 - 1.2 9.2 25.3 0.29 11.2 12.4 3.1 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding Zn_clus PF00172.18 CRK23658.1 - 0.00095 19.2 9.1 0.0015 18.6 9.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RRM_1 PF00076.22 CRK23659.1 - 4.5e-18 64.8 0.0 3.8e-13 49.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CRK23659.1 - 0.054 13.4 0.0 0.26 11.2 0.0 2.0 2 0 0 2 2 2 0 Occluded RNA-recognition motif adh_short PF00106.25 CRK23660.1 - 9.5e-32 110.0 0.0 3.9e-19 68.9 0.0 2.3 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CRK23660.1 - 7.3e-24 84.6 0.1 1.3e-14 54.3 0.2 2.3 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK23660.1 - 7.4e-06 26.0 0.0 0.0013 18.6 0.0 2.2 2 0 0 2 2 2 2 KR domain TcpA PF05946.12 CRK23660.1 - 0.014 15.5 0.0 1 9.5 0.0 2.5 2 0 0 2 2 2 0 Toxin-coregulated pilus subunit TcpA Ras PF00071.22 CRK23661.1 - 2.4e-51 173.5 0.0 2.9e-51 173.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CRK23661.1 - 2.2e-19 69.8 0.0 3.1e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CRK23661.1 - 1.9e-10 40.5 0.0 2.4e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CRK23661.1 - 1.4e-06 28.0 0.2 1.3e-05 24.8 0.1 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CRK23661.1 - 0.0002 21.3 0.0 0.71 9.8 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 CRK23661.1 - 0.00045 20.3 0.0 0.00067 19.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.6 CRK23661.1 - 0.0047 17.1 0.0 0.0084 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 CRK23661.1 - 0.053 12.7 0.0 0.075 12.2 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.6 CRK23661.1 - 0.068 13.5 0.0 0.23 11.8 0.0 1.9 2 1 0 2 2 2 0 AAA ATPase domain Scytalone_dh PF02982.14 CRK23661.1 - 0.12 12.2 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Scytalone dehydratase adh_short PF00106.25 CRK23662.1 - 1.1e-18 67.4 0.0 1.2e-16 60.7 0.0 2.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK23662.1 - 5.9e-09 35.8 0.0 8.5e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK23662.1 - 0.00052 20.0 0.1 0.0014 18.6 0.1 1.7 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 CRK23662.1 - 0.00054 19.9 3.3 0.00064 19.7 0.3 2.2 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 CRK23662.1 - 0.0012 18.3 1.0 0.0022 17.5 0.0 1.9 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 CRK23662.1 - 0.059 12.5 0.0 0.1 11.7 0.0 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain Shugoshin_C PF07557.11 CRK23663.1 - 0.088 12.6 0.0 0.088 12.6 0.0 2.5 3 0 0 3 3 3 0 Shugoshin C terminus AMPK1_CBM PF16561.5 CRK23663.1 - 0.12 12.6 0.6 16 5.8 0.1 2.4 2 0 0 2 2 2 0 Glycogen recognition site of AMP-activated protein kinase EphA2_TM PF14575.6 CRK23663.1 - 0.63 11.0 3.2 2 9.3 3.1 2.0 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF2553 PF10830.8 CRK23663.1 - 2.9 8.8 5.5 0.44 11.4 1.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2553) KilA-N PF04383.13 CRK23665.1 - 4.3e-07 29.8 0.0 5.8e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 KilA-N domain Aldo_ket_red PF00248.21 CRK23666.1 - 9.5e-11 41.4 0.0 1.1e-10 41.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Metallophos PF00149.28 CRK23667.1 - 1e-24 88.2 0.1 1.1e-24 88.1 0.1 1.0 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 CRK23667.1 - 0.028 14.1 0.0 0.037 13.7 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain PH PF00169.29 CRK23674.1 - 0.041 14.4 0.1 0.07 13.6 0.1 1.4 1 0 0 1 1 1 0 PH domain MetOD2 PF18548.1 CRK23674.1 - 0.046 13.8 0.0 0.074 13.2 0.0 1.4 1 0 0 1 1 1 0 Metanogen output domain 2 Glyco_hydro_61 PF03443.14 CRK23702.1 - 5.1e-15 56.0 0.0 5.7e-15 55.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CSD PF00313.22 CRK23702.1 - 0.046 13.6 0.0 0.065 13.1 0.0 1.2 1 0 0 1 1 1 0 'Cold-shock' DNA-binding domain ACT PF01842.25 CRK23703.1 - 3.8e-15 55.4 0.1 7e-15 54.5 0.1 1.5 1 0 0 1 1 1 1 ACT domain ALS_ss_C PF10369.9 CRK23703.1 - 1.2e-14 54.2 0.0 1.3e-13 51.0 0.0 2.3 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT_5 PF13710.6 CRK23703.1 - 2.1e-08 33.9 0.0 4.4e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 ACT domain Myc-LZ PF02344.15 CRK23703.1 - 0.13 12.4 0.4 0.39 10.8 0.4 1.8 1 0 0 1 1 1 0 Myc leucine zipper domain OTCace PF00185.24 CRK23704.1 - 7.2e-44 149.6 0.0 1.3e-43 148.8 0.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 CRK23704.1 - 4.4e-43 146.8 0.1 6.2e-43 146.4 0.1 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain LEA_2 PF03168.13 CRK23705.1 - 1.1e-05 25.8 1.6 0.47 11.0 0.2 3.8 3 1 0 3 3 3 2 Late embryogenesis abundant protein Pox_RNA_pol PF03293.14 CRK23705.1 - 0.033 13.9 0.0 0.081 12.6 0.0 1.5 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase, 18 kD subunit SART-1 PF03343.13 CRK23707.1 - 1.9e-184 614.8 67.8 2.1e-184 614.6 67.8 1.0 1 0 0 1 1 1 1 SART-1 family Glyco_hydro_15 PF00723.21 CRK23708.1 - 1.3e-35 123.1 0.0 1.6e-35 122.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CPT PF07931.12 CRK23709.1 - 2.4e-05 24.3 0.0 4.4e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_28 PF13521.6 CRK23709.1 - 0.0021 18.3 0.0 0.0036 17.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CRK23709.1 - 0.0026 18.3 0.0 0.0064 17.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain G-alpha PF00503.20 CRK23709.1 - 0.029 13.6 0.0 0.04 13.1 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit PRK PF00485.18 CRK23709.1 - 0.041 13.6 0.0 0.12 12.1 0.0 1.7 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.6 CRK23709.1 - 0.072 13.5 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 CRK23709.1 - 0.084 13.0 0.0 0.14 12.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CRK23709.1 - 0.092 13.0 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 CRK23709.1 - 0.13 11.5 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin PTH2 PF01981.16 CRK23710.1 - 1.7e-31 108.9 5.0 1.1e-19 70.8 0.1 2.5 2 1 1 3 3 3 2 Peptidyl-tRNA hydrolase PTH2 BING4CT PF08149.11 CRK23711.1 - 4.9e-38 128.8 0.0 3.6e-34 116.4 0.0 3.5 3 0 0 3 3 3 2 BING4CT (NUC141) domain ANAPC4_WD40 PF12894.7 CRK23711.1 - 6.2e-07 29.6 2.1 1.2 9.5 0.0 5.5 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CRK23711.1 - 2.8e-05 24.8 0.0 0.98 10.4 0.0 4.7 5 0 0 5 5 5 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 CRK23711.1 - 0.0028 16.8 0.0 0.0059 15.7 0.0 1.5 1 0 0 1 1 1 1 Coatomer WD associated region WD40_like PF17005.5 CRK23711.1 - 0.0069 15.8 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 WD40-like domain Cytochrom_D1 PF02239.16 CRK23711.1 - 0.02 13.4 0.1 0.56 8.7 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain RIBIOP_C PF04950.12 CRK23712.1 - 5e-108 361.0 0.0 9.5e-108 360.0 0.0 1.5 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 CRK23712.1 - 2.2e-16 59.7 0.0 5.3e-16 58.5 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain HECT PF00632.25 CRK23713.1 - 3.8e-75 253.2 0.0 5.4e-75 252.7 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) PPI_Ypi1 PF07491.11 CRK23713.1 - 1.3e-49 165.8 3.0 1.1e-23 82.8 0.3 3.0 2 0 0 2 2 2 2 Protein phosphatase inhibitor cobW PF02492.19 CRK23713.1 - 1.5e-05 24.7 0.0 4e-05 23.3 0.0 1.7 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 CRK23713.1 - 0.00082 19.4 0.0 1.7 8.8 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase PAT1 PF09770.9 CRK23714.1 - 0.053 11.8 16.4 0.058 11.7 16.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ndc1_Nup PF09531.10 CRK23714.1 - 0.48 9.1 11.8 0.52 8.9 11.8 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF1980 PF09323.10 CRK23714.1 - 0.55 10.1 2.5 0.94 9.4 2.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) SPX PF03105.19 CRK23714.1 - 0.79 9.6 13.3 1.1 9.1 13.3 1.2 1 0 0 1 1 1 0 SPX domain Presenilin PF01080.17 CRK23714.1 - 1.3 7.7 5.8 1.3 7.7 5.8 1.2 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 CRK23714.1 - 1.4 9.0 2.8 2.1 8.3 2.8 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Nucleo_P87 PF07267.11 CRK23714.1 - 2 7.2 10.1 2.3 7.0 10.1 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 TFIIA PF03153.13 CRK23714.1 - 8.1 6.3 38.6 20 5.0 38.7 1.6 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit L51_S25_CI-B8 PF05047.16 CRK23715.1 - 8.7e-18 64.0 0.0 1.7e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Auts2 PF15336.6 CRK23715.1 - 0.1 12.7 0.9 0.19 11.8 0.9 1.4 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein Ras PF00071.22 CRK23716.1 - 1.4e-22 80.1 0.0 1.8e-22 79.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CRK23716.1 - 0.013 15.7 0.0 0.022 15.0 0.0 1.3 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase DUF5005 PF16396.5 CRK23717.1 - 0.034 12.8 0.0 0.67 8.6 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5005) MMR_HSR1 PF01926.23 CRK23717.1 - 0.08 13.0 0.0 0.24 11.5 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase Zip PF02535.22 CRK23717.1 - 1.2 8.3 2.5 1.8 7.7 2.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter MCM_bind PF09739.9 CRK23717.1 - 3.1 6.1 6.1 48 2.2 5.6 2.1 2 0 0 2 2 2 0 Mini-chromosome maintenance replisome factor L51_S25_CI-B8 PF05047.16 CRK23718.1 - 8.7e-18 64.0 0.0 1.7e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Auts2 PF15336.6 CRK23718.1 - 2.2 8.3 5.3 2.6 8.1 4.5 1.4 1 1 0 1 1 1 0 Autism susceptibility gene 2 protein HECT PF00632.25 CRK23719.1 - 4.1e-77 259.7 0.0 4.8e-77 259.4 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Ras PF00071.22 CRK23720.1 - 2.1e-99 329.8 0.3 5.1e-64 214.8 0.0 2.0 2 0 0 2 2 2 2 Ras family Roc PF08477.13 CRK23720.1 - 2.2e-60 202.1 0.1 3.5e-33 114.4 0.0 2.1 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CRK23720.1 - 1e-22 80.4 0.4 2.2e-12 46.8 0.1 2.0 1 1 1 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.27 CRK23720.1 - 1.8e-10 40.7 0.1 3.9e-05 23.3 0.0 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CRK23720.1 - 1.9e-09 37.2 0.1 0.00094 18.6 0.0 2.1 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CRK23720.1 - 1.7e-07 31.3 0.0 0.017 15.2 0.0 2.4 1 1 1 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CRK23720.1 - 2e-05 24.6 0.2 4.1 7.3 0.0 3.2 3 0 0 3 3 3 3 RsgA GTPase AAA_22 PF13401.6 CRK23720.1 - 0.00015 22.1 0.1 1.3 9.3 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 CRK23720.1 - 0.00017 21.3 0.0 1 9.2 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_7 PF12775.7 CRK23720.1 - 0.00018 21.1 0.0 0.71 9.4 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_24 PF13479.6 CRK23720.1 - 0.00031 20.5 0.5 1.1 8.9 0.0 2.9 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.6 CRK23720.1 - 0.0006 20.2 0.1 1.2 9.5 0.0 2.4 2 1 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 CRK23720.1 - 0.0013 18.8 0.0 2.2 8.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) MCM PF00493.23 CRK23720.1 - 0.0014 17.8 0.0 1.7 7.7 0.0 2.6 3 0 0 3 3 3 2 MCM P-loop domain AAA PF00004.29 CRK23720.1 - 0.0047 17.3 0.0 11 6.4 0.0 3.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 CRK23720.1 - 0.009 15.4 0.0 5.1 6.5 0.0 2.3 2 0 0 2 2 2 2 Bacterial TniB protein Hpr_kinase_C PF07475.12 CRK23720.1 - 0.013 15.0 0.2 6.3 6.3 0.0 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain ABC_tran PF00005.27 CRK23720.1 - 0.055 14.0 0.5 11 6.5 0.2 2.6 2 1 0 2 2 2 0 ABC transporter FeoB_N PF02421.18 CRK23720.1 - 0.055 13.0 0.0 0.89 9.1 0.0 2.6 2 1 0 2 2 2 0 Ferrous iron transport protein B DAP3 PF10236.9 CRK23720.1 - 0.098 11.8 0.0 11 5.1 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 DUF5034 PF16437.5 CRK23720.1 - 0.13 12.3 0.0 4.9 7.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5034) CsrA PF02599.16 CRK23720.1 - 0.51 10.3 2.5 28 4.8 0.2 2.5 2 0 0 2 2 2 0 Global regulator protein family DUF4604 PF15377.6 CRK23721.1 - 0.21 12.0 12.0 0.28 11.6 9.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) AAA PF00004.29 CRK23722.1 - 1.3e-52 177.7 0.0 2.5e-39 134.7 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CRK23722.1 - 2.2e-10 40.2 0.4 2.7e-08 33.5 0.1 3.1 3 0 0 3 3 3 1 AAA+ lid domain AAA_16 PF13191.6 CRK23722.1 - 4.4e-06 27.2 2.9 0.6 10.5 2.4 4.4 2 2 1 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 CRK23722.1 - 0.00021 21.3 0.0 0.018 15.0 0.0 3.2 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 CRK23722.1 - 0.0026 18.0 0.0 0.57 10.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 CRK23722.1 - 0.0036 17.2 0.0 0.14 12.1 0.0 2.6 2 1 0 2 2 2 1 Rad17 P-loop domain RNA_helicase PF00910.22 CRK23722.1 - 0.0041 17.5 0.0 1.5 9.2 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_22 PF13401.6 CRK23722.1 - 0.0046 17.2 2.5 2.5 8.4 0.0 4.0 2 2 2 4 4 4 1 AAA domain RuvB_N PF05496.12 CRK23722.1 - 0.0047 16.7 0.0 0.12 12.1 0.0 2.6 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 CRK23722.1 - 0.0091 15.6 0.1 4.4 6.8 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.6 CRK23722.1 - 0.024 14.7 0.0 1.6 8.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain Vps4_C PF09336.10 CRK23722.1 - 0.028 14.4 0.0 9.9 6.2 0.0 2.8 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain AAA_2 PF07724.14 CRK23722.1 - 0.03 14.4 0.0 0.12 12.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 CRK23722.1 - 0.11 11.9 0.2 0.3 10.4 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI M16C_assoc PF08367.11 CRK23722.1 - 0.14 11.3 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Peptidase M16C associated NACHT PF05729.12 CRK23722.1 - 0.15 12.0 0.5 75 3.2 0.6 3.9 4 1 0 4 4 4 0 NACHT domain AAA_29 PF13555.6 CRK23722.1 - 0.17 11.7 0.0 0.66 9.8 0.0 2.0 2 0 0 2 2 1 0 P-loop containing region of AAA domain SMK-1 PF04802.15 CRK23723.1 - 4.1e-14 52.9 0.4 8.5e-14 51.8 0.4 1.5 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 AAA PF00004.29 CRK23724.1 - 4.2e-11 43.4 0.0 7.7e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CRK23724.1 - 0.011 16.1 2.8 0.19 12.1 2.7 2.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 CRK23724.1 - 0.1 12.8 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CRK23724.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain TMF_DNA_bd PF12329.8 CRK23725.1 - 2e-06 27.7 14.0 7.1e-06 25.9 1.7 3.0 2 1 1 3 3 3 2 TATA element modulatory factor 1 DNA binding bZIP_1 PF00170.21 CRK23725.1 - 2.8e-06 27.3 11.1 0.00058 19.9 0.7 3.2 3 0 0 3 3 3 2 bZIP transcription factor EzrA PF06160.12 CRK23725.1 - 5.1e-05 21.7 5.9 6.8e-05 21.2 5.9 1.2 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA DUF1192 PF06698.11 CRK23725.1 - 0.00012 22.1 5.4 1.8 8.7 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) DUF641 PF04859.12 CRK23725.1 - 0.00018 21.8 11.6 0.00052 20.4 3.0 2.5 1 1 1 2 2 2 1 Plant protein of unknown function (DUF641) Spc7 PF08317.11 CRK23725.1 - 0.00055 18.9 8.1 0.00055 18.9 8.1 1.8 1 1 1 2 2 2 2 Spc7 kinetochore protein Lebercilin PF15619.6 CRK23725.1 - 0.0006 19.5 12.1 0.014 15.1 6.7 2.3 2 0 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease SOGA PF11365.8 CRK23725.1 - 0.00064 20.8 6.0 0.0081 17.3 2.4 2.3 2 0 0 2 2 2 1 Protein SOGA IFT57 PF10498.9 CRK23725.1 - 0.00075 18.6 5.2 0.00086 18.4 5.0 1.3 1 1 0 1 1 1 1 Intra-flagellar transport protein 57 NPV_P10 PF05531.12 CRK23725.1 - 0.0011 19.4 8.0 0.014 15.8 1.5 2.9 2 1 1 3 3 3 1 Nucleopolyhedrovirus P10 protein ZapB PF06005.12 CRK23725.1 - 0.0013 19.1 19.5 0.041 14.3 2.2 3.1 2 1 1 3 3 3 1 Cell division protein ZapB Csm1_N PF18504.1 CRK23725.1 - 0.0017 18.6 10.8 0.038 14.3 0.7 3.5 2 1 1 3 3 3 1 Csm1 N-terminal domain CENP-H PF05837.12 CRK23725.1 - 0.0018 18.7 6.9 0.0018 18.7 6.9 2.1 1 1 1 2 2 2 1 Centromere protein H (CENP-H) DivIC PF04977.15 CRK23725.1 - 0.0033 17.2 16.7 0.32 10.8 1.4 3.4 2 1 1 3 3 3 2 Septum formation initiator AAA_13 PF13166.6 CRK23725.1 - 0.0035 16.1 5.2 0.0042 15.8 5.2 1.0 1 0 0 1 1 1 1 AAA domain TMF_TATA_bd PF12325.8 CRK23725.1 - 0.0035 17.6 16.2 0.079 13.2 0.7 3.0 1 1 2 3 3 3 2 TATA element modulatory factor 1 TATA binding DUF4407 PF14362.6 CRK23725.1 - 0.0042 16.5 14.5 0.23 10.8 4.7 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4407) UPF0242 PF06785.11 CRK23725.1 - 0.0047 17.1 11.4 0.0085 16.2 11.4 1.4 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus DUF4201 PF13870.6 CRK23725.1 - 0.0063 16.3 6.1 0.01 15.6 5.4 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4201) TPR_MLP1_2 PF07926.12 CRK23725.1 - 0.0081 16.2 18.5 0.027 14.5 11.1 2.6 1 1 0 2 2 2 1 TPR/MLP1/MLP2-like protein DUF812 PF05667.11 CRK23725.1 - 0.0085 15.0 5.8 0.012 14.5 5.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) SlyX PF04102.12 CRK23725.1 - 0.011 16.4 18.3 0.28 11.8 1.9 3.5 1 1 2 3 3 3 0 SlyX KxDL PF10241.9 CRK23725.1 - 0.013 15.7 7.9 0.73 10.2 0.8 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein ADIP PF11559.8 CRK23725.1 - 0.017 15.2 18.6 0.054 13.6 1.7 2.9 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding JIP_LZII PF16471.5 CRK23725.1 - 0.02 15.1 8.9 1.2 9.3 0.1 3.3 2 1 1 3 3 3 0 JNK-interacting protein leucine zipper II NRBF2 PF08961.10 CRK23725.1 - 0.023 14.3 1.1 0.023 14.3 1.1 2.8 1 1 2 3 3 3 0 Nuclear receptor-binding factor 2, autophagy regulator FliJ PF02050.16 CRK23725.1 - 0.026 14.7 15.7 0.067 13.4 7.0 2.3 1 1 1 2 2 2 0 Flagellar FliJ protein DUF4200 PF13863.6 CRK23725.1 - 0.033 14.6 13.2 0.077 13.4 3.0 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) PKcGMP_CC PF16808.5 CRK23725.1 - 0.039 13.8 17.1 0.32 10.9 1.0 4.1 3 1 1 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase TolA_bind_tri PF16331.5 CRK23725.1 - 0.043 13.9 15.7 0.72 10.0 2.0 3.1 2 1 1 3 3 3 0 TolA binding protein trimerisation Mod_r PF07200.13 CRK23725.1 - 0.05 13.7 14.5 1.1 9.4 7.1 2.3 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Atg14 PF10186.9 CRK23725.1 - 0.051 12.7 11.3 0.071 12.2 11.3 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF5082 PF16888.5 CRK23725.1 - 0.054 13.8 10.3 0.092 13.0 1.2 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF5082) PKHD_C PF18331.1 CRK23725.1 - 0.081 13.0 0.7 18 5.5 0.1 2.6 2 0 0 2 2 2 0 PKHD-type hydroxylase C-terminal domain DUF4349 PF14257.6 CRK23725.1 - 0.082 12.3 15.4 0.028 13.8 3.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4349) URO-D PF01208.17 CRK23725.1 - 0.084 12.0 0.7 0.14 11.3 0.7 1.3 1 0 0 1 1 1 0 Uroporphyrinogen decarboxylase (URO-D) YabA PF06156.13 CRK23725.1 - 0.086 13.5 0.9 0.086 13.5 0.9 3.0 1 1 2 3 3 3 0 Initiation control protein YabA ATG16 PF08614.11 CRK23725.1 - 0.087 13.0 18.5 0.19 11.9 18.4 1.6 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Spc42p PF11544.8 CRK23725.1 - 0.092 12.7 4.4 0.79 9.8 0.3 2.8 1 1 2 3 3 2 0 Spindle pole body component Spc42p CCDC92 PF14916.6 CRK23725.1 - 0.1 12.4 2.9 0.53 10.1 0.3 2.8 2 0 0 2 2 2 0 Coiled-coil domain of unknown function FlaC_arch PF05377.11 CRK23725.1 - 0.1 13.0 7.2 1.2 9.6 0.2 3.3 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) FapA PF03961.13 CRK23725.1 - 0.11 11.0 4.7 0.15 10.6 4.7 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A HrpB7 PF09486.10 CRK23725.1 - 0.12 12.8 19.7 3.9 7.8 19.7 2.7 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Leu_zip PF15294.6 CRK23725.1 - 0.13 11.7 9.2 0.2 11.1 9.2 1.3 1 0 0 1 1 1 0 Leucine zipper Fez1 PF06818.15 CRK23725.1 - 0.15 12.5 12.9 0.33 11.4 12.9 1.6 1 1 0 1 1 1 0 Fez1 DUF1664 PF07889.12 CRK23725.1 - 0.15 12.1 3.9 0.19 11.8 1.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Sigma54_AID PF00309.20 CRK23725.1 - 0.15 11.9 4.9 2.1 8.3 1.3 2.4 2 0 0 2 2 2 0 Sigma-54 factor, Activator interacting domain (AID) SHE3 PF17078.5 CRK23725.1 - 0.16 11.7 11.7 0.38 10.4 2.8 2.6 1 1 2 3 3 3 0 SWI5-dependent HO expression protein 3 BLOC1_2 PF10046.9 CRK23725.1 - 0.17 12.2 9.9 1.3 9.4 3.0 2.8 1 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TM_PBP2_N PF16296.5 CRK23725.1 - 0.18 12.0 0.0 3.9 7.7 0.0 2.3 2 0 0 2 2 2 0 N-terminal of TM subunit in PBP-dependent ABC transporters HAP1_N PF04849.13 CRK23725.1 - 0.18 11.0 15.5 1.4 8.0 15.5 1.9 1 1 0 1 1 1 0 HAP1 N-terminal conserved region APG6_N PF17675.1 CRK23725.1 - 0.24 11.9 17.8 0.77 10.3 17.7 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF3391 PF11871.8 CRK23725.1 - 0.26 11.8 8.2 0.1 13.2 5.5 1.6 1 1 1 2 2 1 0 Domain of unknown function (DUF3391) GIT_CC PF16559.5 CRK23725.1 - 0.26 11.2 14.3 0.086 12.7 2.1 3.1 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Sulfatase PF00884.23 CRK23725.1 - 0.26 10.6 1.5 0.31 10.4 0.7 1.5 1 1 0 1 1 1 0 Sulfatase TMPIT PF07851.13 CRK23725.1 - 0.31 10.2 5.1 0.2 10.8 3.6 1.4 1 1 0 1 1 1 0 TMPIT-like protein Occludin_ELL PF07303.13 CRK23725.1 - 0.35 11.6 4.9 5.4 7.8 1.2 2.3 1 1 1 2 2 2 0 Occludin homology domain GAS PF13851.6 CRK23725.1 - 0.38 10.1 13.9 1.4 8.2 1.8 2.6 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DASH_Duo1 PF08651.10 CRK23725.1 - 0.45 10.3 4.7 2 8.2 0.3 2.9 2 1 1 3 3 3 0 DASH complex subunit Duo1 HIP1_clath_bdg PF16515.5 CRK23725.1 - 0.46 11.1 16.6 4.8 7.8 5.0 3.0 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 End3 PF12761.7 CRK23725.1 - 0.49 10.6 9.8 0.89 9.7 9.8 1.5 1 1 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 GvpK PF05121.12 CRK23725.1 - 0.51 10.4 6.5 7.8 6.6 0.3 3.0 3 0 0 3 3 3 0 Gas vesicle protein K Golgin_A5 PF09787.9 CRK23725.1 - 0.58 9.6 15.2 0.16 11.4 9.2 1.9 1 1 1 2 2 2 0 Golgin subfamily A member 5 Prefoldin PF02996.17 CRK23725.1 - 0.68 9.9 10.6 1.4 8.9 0.3 3.1 2 1 1 3 3 3 0 Prefoldin subunit Uds1 PF15456.6 CRK23725.1 - 0.74 10.0 13.8 0.27 11.4 7.1 2.2 1 1 1 2 2 2 0 Up-regulated During Septation ERM PF00769.19 CRK23725.1 - 0.84 9.4 20.2 1.9 8.3 20.1 1.5 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Uso1_p115_C PF04871.13 CRK23725.1 - 0.84 10.0 17.8 0.35 11.2 6.7 2.1 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region SYCE1 PF15233.6 CRK23725.1 - 0.87 9.6 12.9 1.4 9.0 6.4 2.1 1 1 1 2 2 2 0 Synaptonemal complex central element protein 1 Fmp27_WPPW PF10359.9 CRK23725.1 - 0.87 8.4 9.3 0.45 9.3 7.1 1.5 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain FAM76 PF16046.5 CRK23725.1 - 0.89 8.8 7.4 2.4 7.5 7.4 1.6 1 1 0 1 1 1 0 FAM76 protein LPP PF04728.13 CRK23725.1 - 0.94 9.9 13.1 2.8 8.4 2.0 3.2 3 0 0 3 3 3 0 Lipoprotein leucine-zipper V_ATPase_I PF01496.19 CRK23725.1 - 1.1 7.1 7.3 1.5 6.6 7.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cut12 PF11500.8 CRK23725.1 - 1.1 9.1 10.6 0.28 11.1 2.8 2.5 1 1 0 2 2 2 0 Spindle pole body formation-associated protein COG2 PF06148.11 CRK23725.1 - 1.2 9.3 8.5 0.89 9.6 0.3 2.5 2 1 1 3 3 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF5339 PF17274.2 CRK23725.1 - 1.3 9.9 6.4 7.3 7.5 1.1 2.9 1 1 1 2 2 2 0 Family of unknown function (DUF5339) DUF948 PF06103.11 CRK23725.1 - 1.3 9.3 5.1 1.9 8.8 0.5 2.7 1 1 2 3 3 2 0 Bacterial protein of unknown function (DUF948) CENP-F_leu_zip PF10473.9 CRK23725.1 - 1.5 8.8 13.3 29 4.7 13.3 2.1 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF16 PF01519.16 CRK23725.1 - 1.6 9.3 6.0 11 6.6 0.9 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF16 Exonuc_VII_L PF02601.15 CRK23725.1 - 1.6 8.2 12.9 4.3 6.8 13.1 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit Herpes_BLRF2 PF05812.12 CRK23725.1 - 1.7 8.8 8.2 0.69 10.1 1.7 2.6 2 1 1 3 3 3 0 Herpesvirus BLRF2 protein CorA PF01544.18 CRK23725.1 - 1.8 7.8 8.2 5.3 6.3 2.3 2.0 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein UCMA PF17085.5 CRK23725.1 - 1.8 8.6 7.1 2.2 8.3 7.1 1.2 1 0 0 1 1 1 0 Unique cartilage matrix associated protein DUF4140 PF13600.6 CRK23725.1 - 1.8 9.0 16.7 4.1 7.9 0.8 3.2 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) DASH_Dam1 PF08653.10 CRK23725.1 - 2.1 8.2 6.3 0.28 11.0 0.4 2.3 3 0 0 3 3 2 0 DASH complex subunit Dam1 CLZ PF16526.5 CRK23725.1 - 2.2 8.7 13.6 0.22 11.9 0.5 3.3 1 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Enkurin PF13864.6 CRK23725.1 - 2.2 8.7 9.7 0.36 11.3 1.3 2.6 1 1 0 2 2 2 0 Calmodulin-binding YlqD PF11068.8 CRK23725.1 - 2.6 8.4 13.2 3.2 8.1 3.2 2.2 1 1 1 2 2 2 0 YlqD protein Jnk-SapK_ap_N PF09744.9 CRK23725.1 - 2.9 8.1 15.9 1.3e+03 -0.5 15.9 2.8 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 TSNAXIP1_N PF15739.5 CRK23725.1 - 2.9 8.3 11.3 7.9 6.9 1.6 2.7 2 1 1 3 3 3 0 Translin-associated factor X-interacting N-terminus Fib_alpha PF08702.10 CRK23725.1 - 3.2 7.9 6.8 1.6 8.9 3.8 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family OmpH PF03938.14 CRK23725.1 - 3.2 8.1 14.2 0.54 10.6 3.2 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DUF724 PF05266.14 CRK23725.1 - 3.2 7.5 9.6 21 4.9 9.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Bap31_Bap29_C PF18035.1 CRK23725.1 - 3.5 7.7 7.4 5.8 7.0 0.6 2.9 3 1 0 3 3 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain bZIP_2 PF07716.15 CRK23725.1 - 4 7.6 19.4 2.7 8.1 2.6 3.7 3 1 1 4 4 4 0 Basic region leucine zipper DUF2730 PF10805.8 CRK23725.1 - 4.1 7.6 5.7 4.1 7.6 0.5 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) NYD-SP28 PF14772.6 CRK23725.1 - 4.7 7.3 14.4 0.57 10.3 3.7 2.6 1 1 1 2 2 2 0 Sperm tail DUF3584 PF12128.8 CRK23725.1 - 4.7 4.6 16.5 2.7 5.4 9.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) RasGAP_C PF03836.15 CRK23725.1 - 4.8 7.3 7.6 1 9.5 2.1 2.2 2 1 0 2 2 2 0 RasGAP C-terminus TSC22 PF01166.18 CRK23725.1 - 5.2 7.5 11.9 1.6 9.1 0.2 3.2 3 0 0 3 3 3 0 TSC-22/dip/bun family GrpE PF01025.19 CRK23725.1 - 5.6 6.6 13.2 6.2e+02 -0.1 13.2 2.5 1 1 0 1 1 1 0 GrpE Cep57_CLD_2 PF14197.6 CRK23725.1 - 6 7.0 20.4 1.2e+02 2.9 10.0 3.0 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 DUF2203 PF09969.9 CRK23725.1 - 6.6 7.5 9.7 7.7 7.3 4.9 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) HALZ PF02183.18 CRK23725.1 - 8 6.8 9.3 12 6.2 0.8 3.5 3 1 0 3 3 3 0 Homeobox associated leucine zipper Med9 PF07544.13 CRK23725.1 - 8 6.6 10.4 3.1 8.0 0.3 3.1 1 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Adaptin_binding PF10199.9 CRK23725.1 - 8.8 7.0 10.4 19 5.9 10.4 1.6 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 His_biosynth PF00977.21 CRK23727.1 - 0.033 13.7 0.0 0.045 13.2 0.0 1.2 1 0 0 1 1 1 0 Histidine biosynthesis protein DUF4096 PF13340.6 CRK23739.1 - 0.081 13.2 1.7 0.18 12.0 1.2 1.8 1 1 1 2 2 2 0 Putative transposase of IS4/5 family (DUF4096) WSC PF01822.19 CRK23753.1 - 6.2e-66 218.6 44.8 1.6e-17 63.4 7.1 4.6 4 0 0 4 4 4 4 WSC domain PQQ_3 PF13570.6 CRK23753.1 - 0.0087 16.5 6.6 0.27 11.8 0.0 5.4 5 0 0 5 5 5 1 PQQ-like domain ASH PF15780.5 CRK23753.1 - 0.018 15.2 0.3 5.6 7.2 0.0 3.4 3 0 0 3 3 3 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 CRK23753.1 - 0.13 12.4 0.2 36 4.6 0.0 3.7 4 0 0 4 4 4 0 Flagellar-associated PapD-like PQQ PF01011.21 CRK23753.1 - 0.14 12.1 0.9 9.1 6.4 0.0 4.0 3 0 0 3 3 3 0 PQQ enzyme repeat PepSY PF03413.19 CRK23753.1 - 0.16 12.6 0.2 0.6 10.7 0.0 2.1 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Prok-RING_1 PF14446.6 CRK23753.1 - 2.8 7.9 7.4 0.16 11.9 0.7 2.4 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 Asparaginase_II PF06089.12 CRK23754.1 - 5.6e-114 380.5 0.5 6.4e-114 380.3 0.5 1.0 1 0 0 1 1 1 1 L-asparaginase II FhuF_C PF11575.8 CRK23755.1 - 0.054 13.4 0.2 0.11 12.5 0.2 1.5 1 0 0 1 1 1 0 FhuF 2Fe-2S C-terminal domain PRCC PF10253.9 CRK23757.1 - 7.6 7.3 8.1 15 6.3 8.1 1.4 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Polysacc_deac_1 PF01522.21 CRK23758.1 - 2.1e-32 111.6 0.0 3.2e-32 111.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 CRK23758.1 - 1.7e-07 30.8 0.0 2e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 DUF2334 PF10096.9 CRK23758.1 - 0.00053 19.7 0.0 0.00081 19.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Sugar_tr PF00083.24 CRK23760.1 - 4.8e-95 319.1 15.7 5.5e-95 318.9 15.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK23760.1 - 7e-26 91.0 29.4 1.6e-19 70.1 13.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 CRK23760.1 - 0.00012 20.7 14.0 0.0023 16.6 0.7 2.5 3 0 0 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.13 CRK23760.1 - 0.00075 18.0 1.1 0.00075 18.0 1.1 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) CMAS PF02353.20 CRK23761.1 - 7.4e-62 209.1 0.0 9.1e-62 208.8 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 CRK23761.1 - 7.4e-09 36.2 0.0 1.4e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CRK23761.1 - 3.1e-08 33.6 0.0 4.7e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK23761.1 - 1.4e-07 32.1 0.0 2.7e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK23761.1 - 0.0082 16.9 0.0 0.015 16.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 CRK23761.1 - 0.032 14.0 0.1 0.057 13.2 0.1 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 CRK23761.1 - 0.059 12.9 0.0 0.11 12.0 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase small domain DOT1 PF08123.13 CRK23761.1 - 0.065 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 DUF1304 PF06993.12 CRK23762.1 - 2.5e-43 146.6 4.0 2.8e-43 146.4 4.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1304) Pyr_redox_3 PF13738.6 CRK23763.1 - 2.6e-16 59.8 0.0 4.4e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CRK23763.1 - 9.4e-16 57.9 0.0 5.3e-13 48.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CRK23763.1 - 2.1e-12 46.9 0.1 2.9e-11 43.1 0.0 2.1 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.19 CRK23763.1 - 2.2e-07 29.7 0.0 5.9e-07 28.3 0.0 1.6 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 CRK23763.1 - 1.8e-05 24.9 0.0 0.00033 20.8 0.0 3.0 4 0 0 4 4 4 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 CRK23763.1 - 3.3e-05 22.8 0.1 0.0014 17.4 0.0 2.3 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox PF00070.27 CRK23763.1 - 4.5e-05 23.9 0.0 0.05 14.2 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CRK23763.1 - 6e-05 22.5 0.0 0.00085 18.7 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 CRK23763.1 - 0.00061 18.9 0.0 0.0054 15.8 0.0 2.4 3 0 0 3 3 3 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 CRK23763.1 - 0.00093 18.4 0.1 0.0017 17.6 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 CRK23763.1 - 0.0055 16.3 0.1 0.18 11.4 0.0 2.4 1 1 1 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 CRK23763.1 - 0.012 14.8 0.2 0.038 13.2 0.1 1.8 2 0 0 2 2 2 0 Thi4 family TrkA_N PF02254.18 CRK23763.1 - 0.012 15.8 0.0 0.07 13.4 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain Trp_halogenase PF04820.14 CRK23763.1 - 0.016 14.1 0.6 0.27 10.1 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase AlaDh_PNT_C PF01262.21 CRK23763.1 - 0.065 12.5 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 CRK23763.1 - 0.33 10.0 0.8 2.4 7.2 0.2 2.2 1 1 1 2 2 2 0 Glucose inhibited division protein A Tyrosinase PF00264.20 CRK23764.1 - 1.6e-25 90.7 0.1 2.1e-24 87.0 0.1 2.0 1 1 0 1 1 1 1 Common central domain of tyrosinase Cpn60_TCP1 PF00118.24 CRK23766.1 - 1.6e-35 122.7 1.0 1.8e-35 122.5 1.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family NatB_MDM20 PF09797.9 CRK23789.1 - 9.8e-50 169.6 0.0 2.1e-49 168.5 0.0 1.5 1 1 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit DUF16 PF01519.16 CRK23790.1 - 0.45 11.0 7.4 54 4.3 0.0 3.4 2 1 0 2 2 2 0 Protein of unknown function DUF16 Fib_alpha PF08702.10 CRK23790.1 - 0.8 9.9 8.6 4 7.6 6.1 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Guanylate_kin PF00625.21 CRK23792.1 - 7.7e-50 169.1 0.0 8.7e-50 168.9 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.6 CRK23792.1 - 0.00023 21.6 0.2 0.0006 20.2 0.2 1.7 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 CRK23792.1 - 0.0022 17.9 0.2 0.0034 17.3 0.2 1.5 1 1 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 CRK23792.1 - 0.0068 16.7 0.1 0.017 15.4 0.0 1.8 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 CRK23792.1 - 0.012 15.7 0.1 0.04 14.0 0.1 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.6 CRK23792.1 - 0.021 15.4 1.0 0.11 13.1 1.0 2.1 1 1 0 1 1 1 0 AAA domain DUF4539 PF15072.6 CRK23792.1 - 0.1 12.7 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4539) ABC_tran PF00005.27 CRK23792.1 - 0.16 12.4 0.2 0.37 11.3 0.1 1.7 2 1 0 2 2 2 0 ABC transporter AAA_7 PF12775.7 CRK23792.1 - 0.18 11.3 0.1 0.43 10.1 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region Mst1_SARAH PF11629.8 CRK23792.1 - 0.2 11.8 1.3 0.27 11.3 0.0 1.9 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 Zn_clus PF00172.18 CRK23793.1 - 8.8e-09 35.3 9.8 1.6e-08 34.5 9.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 CRK23793.1 - 5.4e-06 25.6 0.1 1.3e-05 24.4 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain MFS_1 PF07690.16 CRK23794.1 - 3.9e-33 114.8 47.3 3.8e-21 75.4 19.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ATP1G1_PLM_MAT8 PF02038.16 CRK23794.1 - 0.14 11.6 0.5 0.55 9.7 0.5 2.0 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family DUF4231 PF14015.6 CRK23794.1 - 0.25 11.8 1.0 1.4 9.5 1.0 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) RabGAP-TBC PF00566.18 CRK23795.1 - 9.5e-26 90.8 0.0 1.3e-25 90.3 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SBE2 PF17076.5 CRK23795.1 - 5.1e-07 28.4 1.1 7.6e-07 27.8 1.1 1.1 1 0 0 1 1 1 1 SBE2, cell-wall formation eIF2A PF08662.11 CRK23796.1 - 4.8e-29 101.6 5.1 5.9e-14 52.4 0.0 4.3 4 1 1 5 5 5 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 CRK23796.1 - 0.019 14.8 0.0 0.043 13.7 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 CRK23796.1 - 0.24 12.3 4.1 1.7 9.7 0.1 3.7 4 0 0 4 4 4 0 WD domain, G-beta repeat Cpn60_TCP1 PF00118.24 CRK23797.1 - 7.2e-144 480.1 11.5 8.2e-144 479.9 11.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF5442 PF17514.2 CRK23797.1 - 0.0094 16.1 0.2 0.022 14.9 0.2 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5442) Ribosomal_L20 PF00453.18 CRK23797.1 - 0.057 13.5 0.0 0.15 12.1 0.0 1.8 1 0 0 1 1 1 0 Ribosomal protein L20 CRM1_repeat PF18777.1 CRK23797.1 - 0.1 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat FlgM PF04316.13 CRK23797.1 - 0.2 12.0 2.1 5 7.6 0.0 3.4 3 0 0 3 3 3 0 Anti-sigma-28 factor, FlgM FA_desaturase PF00487.24 CRK23798.1 - 3.2e-23 82.9 25.0 7.8e-23 81.6 25.0 1.6 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 CRK23798.1 - 2.2e-08 34.4 0.0 6.9e-08 32.8 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3474) Peptidase_M35 PF02102.15 CRK23799.1 - 2.9e-82 276.4 17.2 3.5e-82 276.2 17.2 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 CRK23799.1 - 4.2e-45 153.8 5.6 4.2e-45 153.8 5.6 1.8 2 0 0 2 2 2 1 Lysine-specific metallo-endopeptidase Ribonuc_2-5A PF06479.12 CRK23800.1 - 3.7e-43 146.7 0.0 8e-43 145.6 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.25 CRK23800.1 - 4.6e-40 137.6 0.0 4.9e-38 131.0 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK23800.1 - 2.2e-20 73.1 0.0 1e-18 67.6 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.21 CRK23800.1 - 0.00034 20.4 0.1 0.44 10.6 0.0 3.7 3 0 0 3 3 3 1 PQQ enzyme repeat PQQ_2 PF13360.6 CRK23800.1 - 0.0011 18.6 1.5 0.074 12.6 0.1 3.1 2 1 1 3 3 3 2 PQQ-like domain Pkinase_fungal PF17667.1 CRK23800.1 - 0.0011 17.8 0.0 0.0033 16.2 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 CRK23800.1 - 0.0018 17.7 0.0 0.0035 16.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CRK23800.1 - 0.0084 16.1 0.0 0.0084 16.1 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF2946 PF11162.8 CRK23800.1 - 0.24 12.1 2.1 1 10.0 2.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) zf-C3HC4_3 PF13920.6 CRK23801.1 - 4.1e-06 26.6 8.2 4.1e-06 26.6 8.2 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CRK23801.1 - 0.00039 20.2 12.2 0.00039 20.2 12.2 2.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) F-box-like PF12937.7 CRK23802.1 - 0.022 14.7 0.7 0.052 13.4 0.7 1.6 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 CRK23802.1 - 0.037 13.9 0.2 0.075 12.9 0.2 1.5 1 0 0 1 1 1 0 F-box domain SWIB PF02201.18 CRK23803.1 - 1.5e-29 101.6 0.3 3.9e-29 100.3 0.1 1.8 2 0 0 2 2 2 1 SWIB/MDM2 domain DEK_C PF08766.11 CRK23803.1 - 6.6e-16 58.0 1.3 3.1e-15 55.8 1.1 2.0 2 0 0 2 2 2 1 DEK C terminal domain SRP54_N PF02881.19 CRK23803.1 - 0.023 14.9 0.4 0.27 11.5 0.2 2.3 2 0 0 2 2 2 0 SRP54-type protein, helical bundle domain Endotoxin_N PF03945.14 CRK23803.1 - 0.19 11.4 0.0 0.36 10.5 0.0 1.4 1 0 0 1 1 1 0 delta endotoxin, N-terminal domain FXMRP1_C_core PF12235.8 CRK23803.1 - 2.2 8.9 8.2 0.92 10.2 5.4 1.7 1 1 1 2 2 2 0 Fragile X-related 1 protein core C terminal XRCC4 PF06632.12 CRK23803.1 - 2.4 6.9 10.1 3.2 6.5 10.1 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Glyco_hydro_32N PF00251.20 CRK23805.1 - 3.2e-66 224.0 0.7 4.9e-66 223.4 0.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 CRK23805.1 - 2.8e-19 69.7 0.1 5.2e-19 68.8 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Sugar_tr PF00083.24 CRK23806.1 - 3.2e-23 82.3 7.6 3.8e-23 82.1 7.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK23806.1 - 5.7e-08 32.1 11.5 6.7e-08 31.8 11.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3188 PF11384.8 CRK23806.1 - 0.47 10.2 4.0 1 9.2 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3188) Prot_ATP_ID_OB PF16450.5 CRK23807.1 - 3.3e-12 46.2 0.3 4.9e-12 45.6 0.3 1.3 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain BAR PF03114.18 CRK23807.1 - 3.2e-10 40.1 0.1 4.2e-10 39.7 0.1 1.1 1 0 0 1 1 1 1 BAR domain Prot_ATP_OB_N PF17758.1 CRK23807.1 - 0.00065 19.3 0.0 0.0013 18.4 0.0 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB N-terminal domain BRO1 PF03097.18 CRK23813.1 - 5.9e-11 41.8 0.0 6.8e-11 41.6 0.0 1.1 1 0 0 1 1 1 1 BRO1-like domain Glyco_hydro_43 PF04616.14 CRK23815.1 - 0.16 11.2 0.0 0.16 11.2 0.0 1.0 1 0 0 1 1 1 0 Glycosyl hydrolases family 43 F-box-like PF12937.7 CRK23836.1 - 0.03 14.2 0.0 0.089 12.7 0.0 1.9 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 CRK23836.1 - 0.09 12.7 0.0 0.25 11.2 0.0 1.8 1 0 0 1 1 1 0 F-box domain DUF4834 PF16118.5 CRK23838.1 - 0.02 15.9 0.8 0.041 14.8 0.8 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) Gpr1_Fun34_YaaH PF01184.19 CRK23840.1 - 4.3e-43 147.3 14.7 5.6e-43 147.0 14.7 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Rad17 PF03215.15 CRK23842.1 - 1.3e-25 90.4 0.0 2.3e-25 89.6 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain TsaE PF02367.17 CRK23842.1 - 0.0021 18.1 0.0 0.0041 17.1 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 CRK23842.1 - 0.0089 16.3 0.0 0.022 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 CRK23842.1 - 0.011 16.2 0.0 0.028 14.8 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CRK23842.1 - 0.011 16.2 0.0 0.031 14.6 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 CRK23842.1 - 0.024 14.4 0.0 0.052 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CRK23842.1 - 0.075 12.9 0.1 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 NACHT domain ORC6 PF05460.13 CRK23842.1 - 4.2 6.5 8.2 8 5.6 8.2 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Questin_oxidase PF14027.6 CRK23843.1 - 9.3e-115 383.8 8.5 6.7e-90 302.1 1.9 2.1 1 1 1 2 2 2 2 Questin oxidase-like Anti-adapt_IraP PF10796.9 CRK23843.1 - 0.013 16.0 0.0 6.5 7.4 0.0 2.6 2 0 0 2 2 2 0 Sigma-S stabilisation anti-adaptor protein DUF2829 PF11195.8 CRK23843.1 - 0.037 14.3 1.3 13 6.1 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2829) ATP1G1_PLM_MAT8 PF02038.16 CRK23843.1 - 0.19 11.2 0.3 19 4.8 0.0 2.4 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family Tudor_FRX1 PF18336.1 CRK23843.1 - 0.2 11.6 0.6 36 4.4 0.0 2.7 2 0 0 2 2 2 0 Fragile X mental retardation Tudor domain Catalase PF00199.19 CRK23845.1 - 3.3e-152 507.0 0.1 4.1e-152 506.7 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 CRK23845.1 - 3e-16 59.4 0.1 5.2e-16 58.6 0.1 1.4 1 0 0 1 1 1 1 Catalase-related immune-responsive NmrA PF05368.13 CRK23847.1 - 4e-08 33.1 0.0 8.1e-08 32.1 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 CRK23847.1 - 2.4e-05 24.3 0.0 6.7e-05 22.9 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding Catalase PF00199.19 CRK23848.1 - 3.8e-59 200.7 0.0 4.9e-59 200.3 0.0 1.0 1 0 0 1 1 1 1 Catalase NmrA PF05368.13 CRK23849.1 - 6.6e-08 32.4 0.0 1.2e-07 31.5 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 CRK23849.1 - 7.6e-07 29.2 0.0 2.3e-06 27.7 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding Zn_clus PF00172.18 CRK23850.1 - 0.22 11.7 7.0 0.5 10.5 7.0 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Ppx-GppA PF02541.16 CRK23851.1 - 1.7e-29 103.2 0.0 2.6e-29 102.5 0.0 1.3 1 0 0 1 1 1 1 Ppx/GppA phosphatase family BTB PF00651.31 CRK23853.1 - 0.013 15.8 0.0 0.03 14.5 0.0 1.7 1 0 0 1 1 1 0 BTB/POZ domain zf-C3Hc3H PF13891.6 CRK23853.1 - 0.12 12.7 0.1 1.1 9.6 0.0 2.3 2 0 0 2 2 2 0 Potential DNA-binding domain Meth_synt_2 PF01717.18 CRK23854.1 - 6.5e-147 489.0 0.0 8.3e-142 472.2 0.0 2.3 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 CRK23854.1 - 6.3e-118 393.8 0.0 2.2e-111 372.4 0.0 2.8 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.17 CRK23854.1 - 0.00062 19.0 0.0 0.021 14.0 0.0 2.3 2 0 0 2 2 2 1 Uroporphyrinogen decarboxylase (URO-D) Oxidored_FMN PF00724.20 CRK23855.1 - 8.7e-48 163.3 0.0 3e-28 99.1 0.0 3.1 1 1 2 3 3 3 3 NADH:flavin oxidoreductase / NADH oxidase family PTS_IIB PF02302.17 CRK23855.1 - 0.045 14.4 0.4 0.12 13.1 0.1 1.9 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIB subunit Peptidase_C15 PF01470.17 CRK23856.1 - 5.8e-07 29.9 0.0 1.3e-05 25.4 0.0 2.5 2 1 0 2 2 2 1 Pyroglutamyl peptidase HhH-GPD PF00730.25 CRK23856.1 - 0.0044 17.5 0.0 0.015 15.8 0.0 1.8 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein RRM_1 PF00076.22 CRK23857.1 - 5.2e-19 67.8 0.2 1.4e-18 66.5 0.3 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CRK23857.1 - 3.8e-05 23.3 0.0 6.5e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 CRK23857.1 - 0.021 15.1 1.8 1.9 8.7 0.0 2.2 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter RRM_occluded PF16842.5 CRK23857.1 - 0.044 13.6 0.0 0.08 12.8 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif Hemolysin_N PF12563.8 CRK23857.1 - 0.14 11.8 0.1 0.18 11.4 0.1 1.2 1 0 0 1 1 1 0 Hemolytic toxin N terminal SURF4 PF02077.15 CRK23859.1 - 6.8e-95 317.7 7.7 8.4e-95 317.4 7.7 1.1 1 0 0 1 1 1 1 SURF4 family CD99L2 PF12301.8 CRK23859.1 - 0.0068 16.7 0.7 0.0068 16.7 0.7 2.5 2 0 0 2 2 2 1 CD99 antigen like protein 2 Shisa PF13908.6 CRK23859.1 - 0.41 10.9 1.2 65 3.7 0.7 3.1 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator VSP PF03302.13 CRK23859.1 - 1.4 7.7 3.3 2.7 6.8 3.3 1.4 1 0 0 1 1 1 0 Giardia variant-specific surface protein Halogen_Hydrol PF10112.9 CRK23859.1 - 5.5 7.0 5.6 14 5.7 1.9 2.5 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein RRM_1 PF00076.22 CRK23860.1 - 2.4e-27 94.6 0.1 3.6e-11 42.7 0.0 4.4 4 1 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRKCSH_1 PF13015.6 CRK23863.1 - 6.4e-19 68.2 0.1 6.6e-19 68.1 0.1 1.1 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein ATG27 PF09451.10 CRK23863.1 - 0.00066 19.6 0.0 0.0007 19.5 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 RNA_pol_Rpb2_6 PF00562.28 CRK23868.1 - 2.6e-24 86.0 0.8 3e-24 85.8 0.8 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_7 PF04560.20 CRK23868.1 - 5.5e-15 55.5 0.0 7.1e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 Sugar_tr PF00083.24 CRK23869.1 - 1.4e-24 86.8 0.1 1.5e-24 86.7 0.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK23869.1 - 0.00013 21.0 0.3 0.00013 21.0 0.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily zf-C2H2 PF00096.26 CRK23884.1 - 3.7e-10 39.7 15.3 2.6e-05 24.4 1.0 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CRK23884.1 - 9.3e-09 35.3 11.5 5.2e-06 26.6 1.8 2.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CRK23884.1 - 1.9e-07 31.3 15.0 0.00052 20.6 0.8 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CRK23884.1 - 0.00025 20.9 4.3 0.1 12.6 0.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CRK23884.1 - 0.00044 20.4 3.7 0.013 15.8 0.1 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 CRK23884.1 - 0.0072 16.1 10.3 0.29 10.9 0.9 2.7 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 CRK23884.1 - 0.14 11.9 2.4 4.2 7.2 0.2 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type BolA PF01722.18 CRK23884.1 - 0.14 12.4 5.1 5.7 7.3 0.1 3.0 2 1 1 3 3 3 0 BolA-like protein zf-met PF12874.7 CRK23884.1 - 0.52 10.8 4.3 0.65 10.5 0.1 3.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2HE PF16278.5 CRK23884.1 - 2.2 8.8 9.5 1.9 9.0 2.1 2.3 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Ctr PF04145.15 CRK23887.1 - 1.8e-28 100.1 0.6 2.3e-28 99.7 0.6 1.1 1 0 0 1 1 1 1 Ctr copper transporter family SRF-TF PF00319.18 CRK23889.1 - 2e-28 97.6 5.8 1.4e-20 72.5 0.1 2.2 2 0 0 2 2 2 2 SRF-type transcription factor (DNA-binding and dimerisation domain) SRP9-21 PF05486.12 CRK23889.1 - 0.061 13.7 1.0 10 6.6 0.1 2.5 2 1 0 2 2 2 0 Signal recognition particle 9 kDa protein (SRP9) Tetraspanin PF00335.20 CRK23891.1 - 0.0017 18.1 12.7 0.0047 16.7 12.7 1.7 1 1 0 1 1 1 1 Tetraspanin family FxsA PF04186.13 CRK23891.1 - 0.037 14.1 0.5 0.037 14.1 0.5 2.4 2 1 1 3 3 3 0 FxsA cytoplasmic membrane protein DUF4190 PF13828.6 CRK23891.1 - 0.64 9.8 0.0 0.64 9.8 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4190) vATP-synt_E PF01991.18 CRK23894.1 - 3.4e-65 219.2 12.9 3.9e-65 219.0 12.9 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF4314 PF14192.6 CRK23894.1 - 0.051 13.5 0.1 0.083 12.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4314) TTc_toxin_rep PF18807.1 CRK23894.1 - 0.059 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Tripartite Tc toxins repeat DUF2255 PF10012.9 CRK23894.1 - 0.32 11.2 6.1 0.49 10.5 0.7 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2255) Mg_trans_NIPA PF05653.14 CRK23896.1 - 2.2e-17 63.1 8.3 3.7e-17 62.4 8.3 1.3 1 0 0 1 1 1 1 Magnesium transporter NIPA PUNUT PF16913.5 CRK23896.1 - 0.00049 19.4 9.3 0.0093 15.2 9.9 2.5 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport EamA PF00892.20 CRK23896.1 - 0.00077 19.7 0.4 0.00077 19.7 0.4 3.3 2 1 1 3 3 3 2 EamA-like transporter family COX4_pro_2 PF07835.12 CRK23896.1 - 0.15 12.2 0.2 0.15 12.2 0.2 3.1 3 0 0 3 3 3 0 Bacterial aa3 type cytochrome c oxidase subunit IV vATP-synt_E PF01991.18 CRK23899.1 - 3.1e-65 219.3 13.2 3.5e-65 219.2 13.2 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF4314 PF14192.6 CRK23899.1 - 0.051 13.5 0.1 0.083 12.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4314) TTc_toxin_rep PF18807.1 CRK23899.1 - 0.076 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Tripartite Tc toxins repeat DUF2255 PF10012.9 CRK23899.1 - 0.32 11.1 6.1 0.49 10.5 0.7 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2255) FAM178 PF14816.6 CRK23901.1 - 0.0056 15.7 0.2 0.011 14.8 0.2 1.4 1 0 0 1 1 1 1 Family of unknown function, FAM178 Aldedh PF00171.22 CRK23902.1 - 2.2e-112 376.0 0.0 3.1e-112 375.4 0.0 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PhoLip_ATPase_C PF16212.5 CRK23902.1 - 9.9e-78 261.3 27.1 9.9e-78 261.3 27.1 2.7 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CRK23902.1 - 4.4e-19 67.9 0.4 1.3e-18 66.5 0.4 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 CRK23902.1 - 5.8e-11 43.1 0.0 2e-08 34.8 0.0 2.6 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 CRK23902.1 - 0.00033 20.2 0.4 0.0021 17.6 0.0 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 CRK23902.1 - 0.0045 17.0 0.0 0.016 15.2 0.0 1.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CRK23902.1 - 0.035 13.8 0.2 0.088 12.5 0.2 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DEAD PF00270.29 CRK23905.1 - 5.3e-42 143.5 0.0 7.7e-42 143.0 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CRK23905.1 - 1.9e-27 95.8 0.0 7.1e-27 94.0 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 CRK23905.1 - 0.0019 17.0 0.0 0.0027 16.5 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain SecA_DEAD PF07517.14 CRK23905.1 - 0.13 11.6 0.1 1.1 8.5 0.0 2.0 2 0 0 2 2 2 0 SecA DEAD-like domain Robl_LC7 PF03259.17 CRK23907.1 - 2.1e-10 40.3 1.4 7.3e-08 32.1 0.2 2.1 1 1 1 2 2 2 2 Roadblock/LC7 domain LAMTOR5 PF16672.5 CRK23907.1 - 0.059 13.3 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 Ragulator complex protein LAMTOR5 DUF1631 PF07793.11 CRK23909.1 - 1.8 6.9 12.8 2.1 6.7 12.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) F-box-like PF12937.7 CRK23913.1 - 0.065 13.1 0.7 0.19 11.7 0.0 2.2 2 0 0 2 2 2 0 F-box-like CFEM PF05730.11 CRK23915.1 - 0.00013 21.9 2.7 0.00013 21.9 2.7 2.4 3 0 0 3 3 3 1 CFEM domain bVLRF1 PF18826.1 CRK23917.1 - 2.7e-62 209.1 0.0 4e-62 208.5 0.0 1.3 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor Ank_5 PF13857.6 CRK23917.1 - 1.5e-05 25.2 0.0 3.2e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 CRK23917.1 - 0.037 14.5 0.0 0.092 13.2 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeat RPA43_OB PF17875.1 CRK23917.1 - 0.34 11.5 1.7 0.89 10.2 1.3 1.9 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I MT0933_antitox PF14013.6 CRK23919.1 - 0.65 10.3 10.3 3.3 8.1 7.8 2.8 2 2 2 4 4 4 0 MT0933-like antitoxin protein Methyltransf_32 PF13679.6 CRK23921.1 - 0.14 12.2 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CTP_transf_like PF01467.26 CRK23983.1 - 4e-19 69.2 0.0 4.5e-19 69.1 0.0 1.0 1 0 0 1 1 1 1 Cytidylyltransferase-like NIF PF03031.18 CRK23984.1 - 3.7e-10 39.8 0.0 4e-10 39.7 0.0 1.0 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase P33MONOX PF15302.6 CRK24008.1 - 2.1 8.0 9.2 2.1 8.0 9.2 1.0 1 0 0 1 1 1 0 P33 mono-oxygenase EthD PF07110.11 CRK24010.1 - 3.7e-05 24.8 0.1 8.8e-05 23.6 0.1 1.6 2 0 0 2 2 2 1 EthD domain MmlI PF09448.10 CRK24010.1 - 0.017 15.6 0.0 0.021 15.2 0.0 1.3 1 0 0 1 1 1 0 Methylmuconolactone methyl-isomerase UvrB PF12344.8 CRK24010.1 - 0.086 12.7 0.3 0.64 9.9 0.1 2.4 3 0 0 3 3 3 0 Ultra-violet resistance protein B zf-C2H2_2 PF12756.7 CRK24011.1 - 1e-26 93.2 1.4 1.8e-26 92.4 1.4 1.3 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) Sugar_tr PF00083.24 CRK24012.1 - 1e-95 321.3 18.6 1.2e-95 321.1 18.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK24012.1 - 1.2e-29 103.3 24.2 1.7e-22 79.9 9.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 CRK24012.1 - 1.8e-08 33.4 16.2 4e-05 22.4 3.4 2.4 2 1 0 2 2 2 2 MFS/sugar transport protein Alpha-L-AF_C PF06964.12 CRK24014.1 - 4.9e-30 104.8 0.0 6.7e-30 104.4 0.0 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain Glyco_hydro_47 PF01532.20 CRK24015.1 - 1.6e-171 571.3 0.0 1.8e-171 571.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Abhydrolase_6 PF12697.7 CRK24016.1 - 2e-07 31.8 5.5 4e-07 30.9 5.5 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CRK24016.1 - 2.4e-05 24.1 0.1 3.9e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 CRK24016.1 - 4.7e-05 23.6 0.0 0.00012 22.3 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain Ser_hydrolase PF06821.13 CRK24016.1 - 0.057 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase PGAP1 PF07819.13 CRK24016.1 - 0.18 11.5 0.1 0.63 9.7 0.0 1.8 2 0 0 2 2 2 0 PGAP1-like protein DUF2370 PF10176.9 CRK24017.1 - 2.2e-84 282.7 0.0 4.1e-84 281.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) DUF2561 PF10812.8 CRK24017.1 - 0.19 11.7 0.0 0.42 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) Mito_carr PF00153.27 CRK24019.1 - 5.5e-52 173.7 2.8 7.6e-21 73.9 0.1 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein AATase PF07247.12 CRK24021.1 - 0.049 12.2 0.0 0.066 11.7 0.0 1.1 1 0 0 1 1 1 0 Alcohol acetyltransferase Glyco_hydro_18 PF00704.28 CRK24023.1 - 4.7e-18 66.0 0.6 1.4e-17 64.4 0.2 1.7 1 1 1 2 2 2 1 Glycosyl hydrolases family 18 YfmQ PF10787.9 CRK24023.1 - 0.22 11.3 0.0 0.4 10.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein from bacillus cereus group Fer4 PF00037.27 CRK24024.1 - 4.4e-14 51.6 16.4 6.1e-08 32.2 3.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 CRK24024.1 - 5.7e-13 49.2 10.7 9.2e-13 48.6 10.7 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 CRK24024.1 - 8.7e-11 42.6 7.1 8.2e-05 23.5 0.3 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 CRK24024.1 - 2.6e-10 40.3 4.1 6.6e-05 23.0 0.4 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 CRK24024.1 - 6e-09 35.9 21.5 1.1e-06 28.6 12.5 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 CRK24024.1 - 2.1e-08 34.2 10.1 4.4e-08 33.2 10.2 1.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 CRK24024.1 - 8.2e-07 28.8 16.9 0.00021 21.2 5.3 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 CRK24024.1 - 1e-06 28.4 12.2 0.0029 17.6 3.2 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.6 CRK24024.1 - 1.1e-06 29.0 20.5 0.00025 21.5 12.3 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_4 PF12800.7 CRK24024.1 - 2.2e-05 24.6 11.6 0.00069 19.9 2.0 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 CRK24024.1 - 0.00011 22.7 11.9 0.018 15.5 12.8 2.4 1 1 2 3 3 3 3 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.10 CRK24024.1 - 0.0062 16.7 5.5 0.78 10.0 0.5 2.3 1 1 1 2 2 2 2 c-SKI Smad4 binding domain Fer4_18 PF13746.6 CRK24024.1 - 0.035 14.3 9.2 0.52 10.5 1.9 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain ETF_QO PF05187.13 CRK24024.1 - 0.063 13.4 5.2 0.27 11.4 0.4 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_13 PF13370.6 CRK24024.1 - 0.07 13.7 14.6 0.84 10.2 4.0 2.7 2 1 1 3 3 3 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_3 PF12798.7 CRK24024.1 - 0.093 13.7 16.6 0.42 11.7 3.3 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain EPF PF17181.4 CRK24024.1 - 0.46 10.5 5.8 0.18 11.8 0.6 2.2 2 0 0 2 2 2 0 Epidermal patterning factor proteins Fer4_22 PF17179.4 CRK24024.1 - 0.52 11.2 12.1 3.8 8.4 2.0 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain PP-binding PF00550.25 CRK24025.1 - 3.3e-12 46.6 0.1 4.3e-12 46.2 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 CRK24025.1 - 0.00025 21.2 0.3 0.00035 20.7 0.3 1.4 1 1 0 1 1 1 1 Acyl-carrier zf-CCCH PF00642.24 CRK24026.1 - 4.4e-11 42.4 8.5 9.9e-06 25.3 2.0 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CRK24026.1 - 2.3e-10 40.2 16.5 3.6e-05 23.6 3.5 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 CRK24026.1 - 2.8e-10 39.7 10.1 1.9e-05 24.4 2.9 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 CRK24026.1 - 7.5e-09 36.3 5.9 9.6e-05 23.0 0.5 2.4 1 1 1 2 2 2 2 Torus domain zf-CCCH_3 PF15663.5 CRK24026.1 - 3.3e-05 24.1 1.2 6.1e-05 23.2 1.2 1.4 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 CRK24026.1 - 0.00049 20.5 15.8 0.084 13.4 5.4 2.5 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Phage_lysozyme PF00959.19 CRK24028.1 - 7.5e-13 48.9 0.0 1.1e-12 48.4 0.0 1.2 1 0 0 1 1 1 1 Phage lysozyme Phage_lysozyme PF00959.19 CRK24029.1 - 4e-13 49.8 0.0 5.5e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Phage lysozyme NmrA PF05368.13 CRK24030.1 - 9.4e-15 54.8 0.1 1.2e-14 54.5 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 CRK24030.1 - 2.2e-12 47.2 0.8 3.3e-12 46.7 0.1 1.7 2 0 0 2 2 2 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 CRK24030.1 - 0.0004 20.8 0.2 0.0034 17.8 0.1 2.1 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 CRK24030.1 - 0.0024 18.0 0.0 0.0055 16.8 0.0 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.12 CRK24030.1 - 0.042 13.0 0.0 0.072 12.2 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein Goodbye PF17109.5 CRK24031.1 - 7e-32 110.4 1.4 2.1e-31 108.9 0.7 2.2 2 0 0 2 2 2 1 fungal STAND N-terminal Goodbye domain TPR_1 PF00515.28 CRK24031.1 - 9.8e-14 50.5 0.7 0.0036 17.1 0.0 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CRK24031.1 - 5.4e-11 41.7 7.5 0.0016 18.4 0.0 4.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 CRK24031.1 - 2.6e-10 40.4 4.1 7.8e-06 26.1 0.4 5.1 4 1 0 4 4 4 2 Tetratricopeptide repeat AAA_22 PF13401.6 CRK24031.1 - 1.6e-06 28.4 0.0 1.8e-05 25.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain TPR_7 PF13176.6 CRK24031.1 - 4.3e-06 26.4 3.8 0.18 11.9 0.0 4.7 4 0 0 4 4 3 2 Tetratricopeptide repeat AAA_16 PF13191.6 CRK24031.1 - 5.6e-06 26.8 0.2 4.5e-05 23.9 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain TPR_8 PF13181.6 CRK24031.1 - 1.3e-05 25.0 1.4 0.47 10.8 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 CRK24031.1 - 7.4e-05 23.2 7.4 0.036 14.6 0.1 4.9 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 CRK24031.1 - 0.0012 18.6 4.3 4.2 7.4 0.0 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat NACHT PF05729.12 CRK24031.1 - 0.003 17.5 0.0 0.025 14.5 0.0 2.4 2 0 0 2 2 2 1 NACHT domain IstB_IS21 PF01695.17 CRK24031.1 - 0.014 15.1 0.0 0.034 13.9 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein TPR_6 PF13174.6 CRK24031.1 - 0.014 16.0 3.9 9.1 7.2 0.0 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CRK24031.1 - 0.021 15.1 0.9 0.58 10.4 0.1 2.8 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 AAA_33 PF13671.6 CRK24031.1 - 0.079 13.1 0.0 0.52 10.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CRK24031.1 - 0.092 13.1 0.1 2.6 8.5 0.0 2.8 3 0 0 3 3 3 0 RNA helicase PPR PF01535.20 CRK24031.1 - 0.44 10.9 4.9 60 4.2 0.1 5.0 5 0 0 5 5 5 0 PPR repeat zf-RING_2 PF13639.6 CRK24031.1 - 0.72 10.2 5.4 1.8 8.9 5.4 1.7 1 0 0 1 1 1 0 Ring finger domain TPR_14 PF13428.6 CRK24031.1 - 1.5 9.8 15.6 6.8 7.8 0.2 7.1 6 2 2 8 8 7 0 Tetratricopeptide repeat Thioredoxin_6 PF13848.6 CRK24032.1 - 2.5e-09 37.3 0.0 5.7e-09 36.2 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin PF00085.20 CRK24032.1 - 1.1e-07 31.8 0.0 7.3e-07 29.1 0.0 2.4 2 1 0 2 2 2 1 Thioredoxin Helicase_C_2 PF13307.6 CRK24034.1 - 2.6e-58 197.0 0.0 6.2e-58 195.7 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 CRK24034.1 - 4.3e-47 160.0 0.0 7.2e-47 159.3 0.0 1.4 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 CRK24034.1 - 0.0002 21.4 0.1 0.08 12.9 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit DEAD PF00270.29 CRK24034.1 - 0.06 13.1 0.0 1.7 8.4 0.0 2.4 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_22 PF13401.6 CRK24034.1 - 0.066 13.5 0.0 19 5.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain Ribosomal_L27A PF00828.19 CRK24035.1 - 1.1e-18 68.1 0.4 2.7e-18 66.9 0.2 1.7 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Pkinase PF00069.25 CRK24036.1 - 2e-42 145.4 0.0 3.3e-39 134.9 0.0 2.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CRK24036.1 - 7.5e-16 58.2 0.0 5.7e-11 42.2 0.0 3.2 3 1 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 CRK24036.1 - 0.00038 20.4 0.1 0.025 14.5 0.0 2.5 1 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CRK24036.1 - 0.0056 15.5 0.0 0.0088 14.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CRK24036.1 - 0.11 11.8 0.0 7.4 5.8 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Cnd1_N PF12922.7 CRK24037.1 - 2.1e-63 213.1 0.2 1.3e-62 210.5 0.1 2.2 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.7 CRK24037.1 - 6.1e-47 159.7 6.0 9.1e-44 149.4 0.1 3.5 5 0 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CRK24037.1 - 3.8e-10 39.1 3.2 0.015 15.5 0.0 5.7 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 CRK24037.1 - 2.2e-09 37.5 2.4 0.00068 20.0 0.1 4.5 4 1 0 4 4 4 2 HEAT repeats HEAT_EZ PF13513.6 CRK24037.1 - 2.5e-05 24.6 5.2 0.044 14.3 0.2 4.8 4 0 0 4 4 4 1 HEAT-like repeat Adaptin_N PF01602.20 CRK24037.1 - 0.00013 20.7 3.2 0.014 14.0 0.2 3.2 3 0 0 3 3 3 2 Adaptin N terminal region RTP1_C1 PF10363.9 CRK24037.1 - 0.00046 20.4 0.2 0.24 11.6 0.0 3.7 3 1 1 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 Cnd3 PF12719.7 CRK24037.1 - 0.0066 15.7 6.3 0.0077 15.5 2.1 3.2 2 2 1 3 3 3 1 Nuclear condensing complex subunits, C-term domain DUF5445 PF17520.2 CRK24037.1 - 0.074 12.9 0.0 1.8 8.4 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5445) GRIM-19 PF06212.12 CRK24039.1 - 3.5e-22 78.8 0.1 1.3e-21 76.9 0.1 2.0 1 1 0 1 1 1 1 GRIM-19 protein NIF PF03031.18 CRK24039.1 - 3.4e-17 62.6 0.0 7.8e-17 61.5 0.0 1.6 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase BRCT PF00533.26 CRK24039.1 - 0.0029 18.0 0.0 0.0087 16.4 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 CRK24039.1 - 0.036 14.0 0.0 0.086 12.7 0.0 1.6 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain PTCB-BRCT PF12738.7 CRK24039.1 - 0.057 13.4 0.2 0.15 12.1 0.2 1.7 1 0 0 1 1 1 0 twin BRCT domain NYN PF01936.18 CRK24040.1 - 7.9e-30 104.3 0.0 1.3e-29 103.6 0.0 1.3 1 0 0 1 1 1 1 NYN domain OST-HTH PF12872.7 CRK24040.1 - 4.1e-15 55.3 0.0 7.5e-15 54.5 0.0 1.4 1 0 0 1 1 1 1 OST-HTH/LOTUS domain Fe-S_assembly PF04384.13 CRK24040.1 - 0.0015 19.1 0.0 0.0027 18.3 0.0 1.4 1 0 0 1 1 1 1 Iron-sulphur cluster assembly Glyco_transf_28 PF03033.20 CRK24041.1 - 1.3e-29 103.1 0.0 4.8e-29 101.2 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.20 CRK24041.1 - 7.6e-27 93.5 0.9 1.4e-18 66.9 0.0 2.9 3 0 0 3 3 3 2 GRAM domain PH PF00169.29 CRK24041.1 - 1.8e-11 44.5 0.4 1.1e-10 41.9 0.0 2.4 3 0 0 3 3 3 1 PH domain PH_11 PF15413.6 CRK24041.1 - 0.0018 18.7 0.3 0.03 14.7 0.3 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain UDPGT PF00201.18 CRK24041.1 - 0.0029 16.5 0.1 0.0071 15.2 0.1 1.6 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_8 PF15409.6 CRK24041.1 - 0.0066 16.7 0.0 0.016 15.5 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 CRK24041.1 - 0.02 15.0 0.0 0.046 13.8 0.0 1.6 1 0 0 1 1 1 0 PH domain WD40 PF00400.32 CRK24042.1 - 8.5e-08 32.7 5.1 0.15 13.0 0.0 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat NYD-SP28 PF14772.6 CRK24043.1 - 0.016 15.3 0.3 0.05 13.7 0.3 1.9 1 0 0 1 1 1 0 Sperm tail Yip1 PF04893.17 CRK24044.1 - 0.059 13.1 0.0 0.083 12.6 0.0 1.1 1 0 0 1 1 1 0 Yip1 domain Pectate_lyase PF03211.13 CRK24045.1 - 2.5e-77 259.1 9.7 3.1e-77 258.7 9.7 1.1 1 0 0 1 1 1 1 Pectate lyase MFS_1 PF07690.16 CRK24046.1 - 4.4e-45 154.1 40.0 4.4e-45 154.1 40.0 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK24046.1 - 6.8e-12 45.0 22.2 6.8e-12 45.0 15.6 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter Adeno_E4_34 PF04528.13 CRK24046.1 - 0.01 15.7 0.2 0.26 11.1 0.3 2.3 2 0 0 2 2 2 0 Adenovirus early E4 34 kDa protein conserved region ketoacyl-synt PF00109.26 CRK24047.1 - 1e-78 264.4 0.0 1.8e-78 263.6 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 CRK24047.1 - 1.1e-46 159.8 0.0 2e-46 159.0 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 CRK24047.1 - 5.9e-21 75.0 0.0 1e-20 74.2 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.25 CRK24047.1 - 2.6e-19 69.3 4.1 9.6e-09 35.5 0.4 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site Thioesterase PF00975.20 CRK24047.1 - 3e-18 66.8 0.0 9.9e-18 65.1 0.0 2.0 2 0 0 2 2 2 1 Thioesterase domain SAT PF16073.5 CRK24047.1 - 1.1e-17 64.6 0.7 3.7e-15 56.3 0.0 3.2 2 1 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis KAsynt_C_assoc PF16197.5 CRK24047.1 - 5.7e-09 36.4 0.0 1.7e-08 34.9 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Abhydrolase_6 PF12697.7 CRK24047.1 - 3.9e-05 24.4 0.2 0.0018 18.9 0.0 2.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Thiolase_N PF00108.23 CRK24047.1 - 0.0005 19.5 0.1 0.001 18.5 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Abhydrolase_3 PF07859.13 CRK24047.1 - 0.066 13.1 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold AMP-binding PF00501.28 CRK24048.1 - 6.5e-34 117.2 0.1 2e-33 115.6 0.0 1.7 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.12 CRK24048.1 - 2.8e-19 69.3 0.0 4.5e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 CRK24048.1 - 7.5e-06 25.6 0.0 1.5e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 CRK24048.1 - 0.00054 20.3 0.0 0.0026 18.1 0.0 2.3 1 1 0 1 1 1 1 Phosphopantetheine attachment site Semialdhyde_dh PF01118.24 CRK24048.1 - 0.014 15.8 0.0 0.032 14.7 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 CRK24048.1 - 0.028 14.3 0.1 0.066 13.1 0.1 1.6 1 0 0 1 1 1 0 KR domain Opi1 PF08618.10 CRK24049.1 - 3.6e-38 131.9 7.4 1.7e-25 90.2 1.3 3.1 2 1 1 3 3 3 3 Transcription factor Opi1 Opi1 PF08618.10 CRK24050.1 - 2.1e-08 33.9 7.6 7e-06 25.5 0.1 3.2 3 0 0 3 3 3 2 Transcription factor Opi1 eIF3_subunit PF08597.10 CRK24051.1 - 0.0031 17.5 0.1 0.004 17.1 0.1 1.1 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit SR-25 PF10500.9 CRK24051.1 - 0.028 14.0 0.2 0.028 14.0 0.2 1.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Chorion_2 PF03964.15 CRK24051.1 - 0.068 14.0 5.0 0.2 12.5 5.0 1.8 1 0 0 1 1 1 0 Chorion family 2 IMUP PF15761.5 CRK24051.1 - 0.11 13.2 2.6 0.2 12.4 2.6 1.3 1 0 0 1 1 1 0 Immortalisation up-regulated protein eIF3_subunit PF08597.10 CRK24052.1 - 0.08 12.8 0.0 0.1 12.5 0.0 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit TMEM154 PF15102.6 CRK24052.1 - 0.6 10.0 1.7 1.3e+02 2.5 0.0 3.1 3 0 0 3 3 3 0 TMEM154 protein family 2-Hacid_dh_C PF02826.19 CRK24053.1 - 9.4e-37 126.1 0.0 1.3e-36 125.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CRK24053.1 - 1.9e-09 37.3 0.1 2.5e-09 36.9 0.1 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 CRK24053.1 - 0.0011 19.1 0.0 0.0019 18.4 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 CRK24053.1 - 0.039 14.5 0.2 0.092 13.3 0.2 1.6 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent HAT_KAT11 PF08214.11 CRK24054.1 - 1.9e-94 316.8 0.0 2.4e-94 316.5 0.0 1.1 1 0 0 1 1 1 1 Histone acetylation protein Glyco_hydro_63N PF16923.5 CRK24054.1 - 0.1 12.7 0.2 0.6 10.2 0.1 2.1 2 0 0 2 2 2 0 Glycosyl hydrolase family 63 N-terminal domain Ribonucleas_3_3 PF14622.6 CRK24055.1 - 1.1e-30 106.4 0.0 2.1e-30 105.5 0.0 1.5 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 CRK24055.1 - 0.038 14.6 0.0 0.22 12.2 0.0 2.3 1 1 0 1 1 1 0 Ribonuclease III domain Thymidylate_kin PF02223.17 CRK24056.1 - 1.2e-41 142.4 0.0 4.9e-40 137.2 0.0 2.1 2 0 0 2 2 2 1 Thymidylate kinase AAA_28 PF13521.6 CRK24056.1 - 7.4e-05 23.1 0.0 0.00017 21.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 CRK24056.1 - 0.0056 16.2 0.0 0.0098 15.4 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 CRK24056.1 - 0.042 14.4 0.0 0.092 13.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain Asp PF00026.23 CRK24057.1 - 1.1e-16 61.2 0.0 4.3e-14 52.6 0.0 2.5 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 CRK24057.1 - 0.00071 19.9 1.2 0.0031 17.8 0.0 2.2 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal adh_short PF00106.25 CRK24058.1 - 1.7e-36 125.6 0.0 2.8e-27 95.4 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CRK24058.1 - 1.6e-23 83.5 0.0 3.1e-16 59.7 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK24058.1 - 1.1e-10 41.7 0.0 1.6e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 CRK24058.1 - 0.0052 16.0 0.0 0.0075 15.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 CRK24058.1 - 0.0072 15.8 0.0 0.029 13.8 0.0 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CRK24058.1 - 0.03 13.8 0.0 0.093 12.2 0.0 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family E1-E2_ATPase PF00122.20 CRK24059.1 - 4.4e-38 130.6 14.3 3.9e-32 111.2 0.0 3.6 3 1 1 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 CRK24059.1 - 5.1e-27 94.8 6.7 5.1e-27 94.8 6.7 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 CRK24059.1 - 2.9e-20 73.4 0.0 3.7e-19 69.8 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CRK24059.1 - 4.6e-17 61.9 0.0 8.9e-17 61.0 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 CRK24059.1 - 2.1e-14 52.9 0.0 4.5e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CRK24059.1 - 0.00013 21.9 0.6 0.00026 20.8 0.2 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Na_Pi_cotrans PF02690.15 CRK24059.1 - 0.01 16.0 3.6 0.01 16.0 3.6 2.2 2 0 0 2 2 2 1 Na+/Pi-cotransporter DUF2463 PF09591.10 CRK24059.1 - 0.093 12.6 0.9 0.21 11.4 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2463) Glyco_hydro_2_C PF02836.17 CRK24060.1 - 1.9e-102 342.4 0.0 3.1e-102 341.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 CRK24060.1 - 9.6e-68 228.4 0.0 2e-67 227.4 0.0 1.5 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 CRK24060.1 - 8.5e-25 87.6 0.1 2.2e-24 86.2 0.1 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain DUF4981 PF16353.5 CRK24060.1 - 1.8e-21 76.4 0.7 8.7e-21 74.2 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function(DUF4981) PQ-loop PF04193.14 CRK24060.1 - 2.4e-17 62.4 1.3 6.3e-13 48.3 0.1 2.6 2 0 0 2 2 2 2 PQ loop repeat Glyco_hydro_2 PF00703.21 CRK24060.1 - 1.2e-15 58.1 0.3 3.2e-15 56.7 0.3 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Peptidase_U4 PF03419.13 CRK24060.1 - 0.11 11.8 3.7 0.18 11.0 3.7 1.2 1 0 0 1 1 1 0 Sporulation factor SpoIIGA HsbA PF12296.8 CRK24061.1 - 1.3e-24 86.9 8.7 1.3e-24 86.9 8.7 2.0 1 1 1 2 2 2 1 Hydrophobic surface binding protein A DUF4131 PF13567.6 CRK24061.1 - 0.047 13.4 0.2 0.08 12.6 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) OmpH PF03938.14 CRK24061.1 - 0.31 11.4 4.0 0.6 10.4 3.4 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) TAFII28 PF04719.14 CRK24062.1 - 1.5e-29 102.0 0.0 2.5e-29 101.2 0.0 1.4 1 0 0 1 1 1 1 hTAFII28-like protein conserved region GTP_cyclohydroI PF01227.22 CRK24063.1 - 1.6e-74 249.2 1.3 2.3e-74 248.7 1.3 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 CRK24063.1 - 0.00067 19.8 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 QueF-like protein Macoilin PF09726.9 CRK24063.1 - 0.07 11.7 4.6 0.076 11.6 4.6 1.1 1 0 0 1 1 1 0 Macoilin family DUF3638 PF12340.8 CRK24063.1 - 0.074 12.4 0.1 0.14 11.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3638) OmpH PF03938.14 CRK24063.1 - 0.099 13.0 1.4 0.89 9.9 0.0 2.6 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) Ndc1_Nup PF09531.10 CRK24063.1 - 0.33 9.6 1.4 0.33 9.6 1.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Apt1 PF10351.9 CRK24063.1 - 1.8 7.4 10.2 2.5 6.9 10.2 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain CDC45 PF02724.14 CRK24063.1 - 6.7 4.9 9.8 9.9 4.3 9.8 1.3 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 CRK24063.1 - 8.2 5.1 10.1 11 4.6 10.1 1.2 1 0 0 1 1 1 0 Presenilin Aminotran_1_2 PF00155.21 CRK24065.1 - 1.5e-38 132.9 0.0 1.8e-38 132.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_3 PF00202.21 CRK24065.1 - 0.05 12.3 0.0 0.074 11.7 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-III Hap4_Hap_bind PF10297.9 CRK24066.1 - 1.5e-08 34.5 6.9 1.5e-08 34.5 6.9 2.7 3 0 0 3 3 2 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.21 CRK24066.1 - 2.2e-05 24.4 11.7 6.3e-05 23.0 11.7 1.7 1 1 0 1 1 1 1 bZIP transcription factor JAKMIP_CC3 PF16034.5 CRK24066.1 - 0.0067 16.4 5.7 0.0067 16.4 5.7 2.3 3 0 0 3 3 3 1 JAKMIP CC3 domain Mt_ATP-synt_D PF05873.12 CRK24066.1 - 0.01 15.7 1.6 0.02 14.7 1.6 1.4 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) Fmp27_WPPW PF10359.9 CRK24066.1 - 0.05 12.5 6.6 0.098 11.5 6.6 1.4 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Cdh1_DBD_1 PF18196.1 CRK24066.1 - 0.075 13.3 3.5 0.15 12.4 3.5 1.4 1 0 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 bZIP_2 PF07716.15 CRK24066.1 - 0.082 13.0 14.5 0.14 12.2 7.5 2.4 1 1 1 2 2 2 0 Basic region leucine zipper dsrm PF00035.26 CRK24066.1 - 0.1 13.3 0.0 0.3 11.8 0.0 1.7 1 0 0 1 1 1 0 Double-stranded RNA binding motif Atg14 PF10186.9 CRK24066.1 - 0.22 10.6 3.9 0.44 9.6 3.9 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TPR_MLP1_2 PF07926.12 CRK24066.1 - 0.66 10.0 11.2 0.15 12.2 6.9 2.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF3584 PF12128.8 CRK24066.1 - 0.66 7.4 9.9 0.92 6.9 9.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HIP1_clath_bdg PF16515.5 CRK24066.1 - 2.4 8.8 14.1 0.12 13.0 7.6 2.0 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Tmemb_cc2 PF10267.9 CRK24066.1 - 6.6 5.8 9.7 1 8.4 4.3 2.1 2 1 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein COG2 PF06148.11 CRK24067.1 - 4.8e-26 91.4 0.1 6.9e-26 90.9 0.1 1.2 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.11 CRK24067.1 - 5e-05 23.3 0.0 0.00014 21.9 0.0 1.8 1 1 0 1 1 1 1 Vps51/Vps67 COG5 PF10392.9 CRK24067.1 - 0.00083 19.5 0.1 0.0019 18.4 0.1 1.6 1 1 0 1 1 1 1 Golgi transport complex subunit 5 Spc7 PF08317.11 CRK24067.1 - 0.0027 16.6 0.2 0.0042 16.0 0.2 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Dor1 PF04124.12 CRK24067.1 - 0.026 13.2 0.2 0.038 12.7 0.2 1.2 1 0 0 1 1 1 0 Dor1-like family Vps54_N PF10475.9 CRK24067.1 - 0.044 13.1 0.0 0.078 12.3 0.0 1.4 1 1 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex Fez1 PF06818.15 CRK24067.1 - 0.077 13.4 0.1 0.098 13.1 0.1 1.3 1 0 0 1 1 1 0 Fez1 HrpB7 PF09486.10 CRK24067.1 - 3.6 7.9 8.3 0.28 11.6 1.3 2.6 3 1 1 4 4 4 0 Bacterial type III secretion protein (HrpB7) Ribosomal_L1 PF00687.21 CRK24068.1 - 3.8e-23 82.3 0.5 1.3e-22 80.6 0.3 1.7 1 1 1 2 2 2 1 Ribosomal protein L1p/L10e family Salt_tol_Pase PF09506.10 CRK24068.1 - 0.11 11.2 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Glucosylglycerol-phosphate phosphatase (Salt_tol_Pase) tRNA-synt_1c_C PF03950.18 CRK24070.1 - 1.1e-21 77.5 0.0 1.2e-21 77.3 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain WSC PF01822.19 CRK24071.1 - 3.5e-29 100.8 21.6 2.3e-17 62.9 2.9 4.7 5 0 0 5 5 5 2 WSC domain PT PF04886.12 CRK24071.1 - 0.0037 16.8 37.0 0.069 12.7 37.0 2.6 1 1 0 1 1 1 1 PT repeat DUF4106 PF13388.6 CRK24071.1 - 0.28 10.4 11.2 0.43 9.8 11.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) CDC45 PF02724.14 CRK24071.1 - 5.3 5.2 5.0 7.7 4.7 5.0 1.2 1 0 0 1 1 1 0 CDC45-like protein RTA1 PF04479.13 CRK24072.1 - 1.7e-61 207.5 7.3 1.7e-61 207.5 7.3 1.7 1 1 1 2 2 2 1 RTA1 like protein Caveolin PF01146.17 CRK24072.1 - 0.35 10.8 1.9 0.51 10.3 1.3 1.7 1 1 0 1 1 1 0 Caveolin DP PF08781.10 CRK24073.1 - 0.12 12.2 0.2 0.19 11.6 0.2 1.2 1 0 0 1 1 1 0 Transcription factor DP Glyco_hydro_61 PF03443.14 CRK24074.1 - 5.1e-59 199.7 0.2 7.7e-59 199.1 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 CRK24074.1 - 5.9e-12 45.3 10.8 2e-11 43.7 10.8 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain Mito_carr PF00153.27 CRK24075.1 - 1.3e-14 53.8 3.4 4.9e-05 23.2 0.1 4.6 3 2 0 3 3 3 3 Mitochondrial carrier protein Fer2 PF00111.27 CRK24076.1 - 9.8e-12 44.7 3.1 1.4e-11 44.2 3.1 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Rrp15p PF07890.12 CRK24077.1 - 2.9e-46 157.1 22.7 1.6e-34 119.1 10.8 4.8 5 0 0 5 5 5 2 Rrp15p Toprim_4 PF13662.6 CRK24077.1 - 5.7e-08 33.1 1.7 0.013 16.0 0.1 2.6 2 0 0 2 2 2 2 Toprim domain Toprim PF01751.22 CRK24077.1 - 0.00017 21.8 0.1 1 9.6 0.0 2.7 2 0 0 2 2 2 2 Toprim domain DNA_gyraseB_C PF00986.21 CRK24077.1 - 0.039 14.1 1.1 13 6.1 0.1 2.6 2 0 0 2 2 2 0 DNA gyrase B subunit, carboxyl terminus Myc_N PF01056.18 CRK24077.1 - 1.7 8.4 34.3 7.8 6.3 13.8 2.4 1 1 1 2 2 2 0 Myc amino-terminal region tRNA-synt_1c PF00749.21 CRK24078.1 - 7.5e-105 350.3 0.0 9.7e-105 349.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 CRK24078.1 - 2.2e-41 141.6 0.0 3.6e-41 140.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_1e PF01406.19 CRK24078.1 - 0.00098 18.6 0.2 0.0028 17.0 0.1 1.6 1 1 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain WSC PF01822.19 CRK24079.1 - 4.2e-29 100.6 21.1 1e-16 60.9 3.2 4.5 4 1 1 5 5 5 2 WSC domain BNIP3 PF06553.12 CRK24079.1 - 1.4 8.6 0.0 1.4 8.6 0.0 2.3 3 0 0 3 3 3 0 BNIP3 CDC45 PF02724.14 CRK24079.1 - 8 4.6 8.9 11 4.1 8.9 1.1 1 0 0 1 1 1 0 CDC45-like protein RTA1 PF04479.13 CRK24080.1 - 4.2e-64 216.0 8.2 4.2e-64 216.0 8.2 1.5 2 0 0 2 2 2 1 RTA1 like protein DUF5423 PF17461.2 CRK24081.1 - 0.15 10.9 0.2 0.22 10.4 0.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5423) Glyco_hydro_61 PF03443.14 CRK24082.1 - 3.2e-59 200.3 0.3 4.2e-59 199.9 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 CRK24082.1 - 1.3e-12 47.4 12.3 5.3e-12 45.5 12.3 2.1 1 0 0 1 1 1 1 Fungal cellulose binding domain Mito_carr PF00153.27 CRK24083.1 - 8.6e-15 54.4 4.7 7.2e-05 22.6 0.1 4.6 3 2 0 3 3 3 3 Mitochondrial carrier protein DUF883 PF05957.13 CRK24083.1 - 0.086 13.4 0.1 0.22 12.1 0.1 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Trp_leader2 PF08056.11 CRK24083.1 - 0.16 12.0 1.3 0.33 11.0 1.3 1.5 1 0 0 1 1 1 0 Tryptophan operon leader peptide Fer2 PF00111.27 CRK24084.1 - 9.6e-12 44.7 3.1 1.4e-11 44.2 3.1 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain WSC PF01822.19 CRK24086.1 - 5.2e-12 45.8 6.9 5.2e-12 45.8 6.9 3.1 2 1 0 2 2 2 1 WSC domain Glyco_hydro_88 PF07470.13 CRK24087.1 - 1.9e-61 208.1 1.6 2.5e-61 207.7 1.6 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 PARP PF00644.20 CRK24088.1 - 3.9e-60 202.8 0.0 5.1e-60 202.4 0.0 1.1 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 CRK24088.1 - 6.8e-21 74.8 0.2 9.7e-21 74.3 0.2 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WSC PF01822.19 CRK24089.1 - 4.7e-12 45.9 6.9 4.7e-12 45.9 6.9 3.1 2 1 0 2 2 2 1 WSC domain Glyco_hydro_88 PF07470.13 CRK24090.1 - 1.4e-61 208.5 1.9 1.8e-61 208.1 1.9 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 PARP PF00644.20 CRK24091.1 - 4.1e-60 202.7 0.0 8.6e-60 201.7 0.0 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 CRK24091.1 - 1.6e-45 154.5 0.7 3.1e-45 153.6 0.7 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 CRK24091.1 - 4.7e-21 74.6 0.5 1.2e-20 73.3 0.5 1.7 1 0 0 1 1 1 1 WGR domain BRCT PF00533.26 CRK24091.1 - 1.2e-07 32.0 0.0 3.8e-07 30.4 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 CRK24091.1 - 0.00071 19.5 0.2 0.0015 18.4 0.2 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 CRK24091.1 - 0.004 17.5 0.0 0.0087 16.5 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain F-box PF00646.33 CRK24092.1 - 4.6e-05 23.2 1.5 0.51 10.3 0.0 3.4 3 0 0 3 3 3 2 F-box domain DUF1024 PF06260.12 CRK24092.1 - 0.00014 22.0 0.0 0.56 10.5 0.0 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF1024) F-box-like PF12937.7 CRK24092.1 - 0.00024 20.9 0.0 1.2 9.0 0.0 2.9 2 0 0 2 2 2 2 F-box-like RNA_pol_I_TF PF04090.12 CRK24092.1 - 0.035 13.6 0.0 9.9 5.6 0.0 2.4 2 0 0 2 2 2 0 RNA polymerase I specific initiation factor TraY PF05509.11 CRK24092.1 - 0.045 13.8 0.0 6.3 6.9 0.0 2.4 2 0 0 2 2 2 0 TraY domain CysG_dimeriser PF10414.9 CRK24092.1 - 0.17 11.6 4.4 7.2 6.4 0.3 2.6 2 0 0 2 2 2 0 Sirohaem synthase dimerisation region LRR_4 PF12799.7 CRK24092.1 - 0.88 10.1 5.4 18 5.9 0.5 3.1 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) WGR PF05406.15 CRK24093.1 - 3e-11 43.2 0.3 6.4e-11 42.2 0.3 1.5 1 0 0 1 1 1 1 WGR domain BRCT PF00533.26 CRK24093.1 - 6.5e-08 32.8 0.1 1.5e-07 31.7 0.0 1.7 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 CRK24093.1 - 0.0004 20.3 0.1 0.00083 19.3 0.1 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 CRK24093.1 - 0.00071 19.9 0.0 0.0014 19.0 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Peptidase_S28 PF05577.12 CRK24094.1 - 2.4e-52 178.2 0.0 4.1e-42 144.5 0.0 2.2 2 0 0 2 2 2 2 Serine carboxypeptidase S28 GMC_oxred_N PF00732.19 CRK24094.1 - 8.6e-47 159.9 0.1 1.4e-46 159.3 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CRK24094.1 - 4.2e-30 105.2 0.1 8e-30 104.3 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 CRK24094.1 - 0.0092 16.2 0.2 0.037 14.2 0.2 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CRK24094.1 - 0.013 14.7 0.0 0.026 13.8 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 CRK24094.1 - 0.024 13.7 0.0 0.036 13.1 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 CRK24094.1 - 0.13 12.3 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding DUF2920 PF11144.8 CRK24094.1 - 0.21 10.7 0.0 0.34 10.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Glyco_hydro_11 PF00457.17 CRK24095.1 - 4.3e-78 261.0 15.5 5.5e-78 260.7 15.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Glyco_hydro_11 PF00457.17 CRK24096.1 - 3.4e-56 189.7 6.2 4e-56 189.5 6.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 tRNA-synt_1e PF01406.19 CRK24097.1 - 3e-110 368.3 0.0 4.8e-110 367.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 CRK24097.1 - 0.00019 20.3 0.2 0.28 9.9 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) DALR_2 PF09190.11 CRK24097.1 - 0.12 12.8 3.3 0.13 12.7 0.0 2.6 2 0 0 2 2 2 0 DALR domain GCD14 PF08704.10 CRK24098.1 - 2.7e-57 194.3 0.0 4.1e-43 147.8 0.0 2.2 2 0 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit GMC_oxred_N PF00732.19 CRK24099.1 - 2.5e-21 76.3 0.3 3.2e-21 76.0 0.3 1.1 1 0 0 1 1 1 1 GMC oxidoreductase Thi4 PF01946.17 CRK24099.1 - 0.00057 19.2 0.1 0.00092 18.5 0.1 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 CRK24099.1 - 0.0013 18.9 0.2 0.0041 17.3 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 CRK24099.1 - 0.0029 16.7 0.0 0.004 16.3 0.0 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 CRK24099.1 - 0.014 15.0 0.3 0.017 14.8 0.3 1.3 1 1 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 CRK24099.1 - 0.019 14.9 0.0 0.028 14.4 0.0 1.3 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 CRK24099.1 - 0.046 12.8 0.0 0.066 12.3 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.19 CRK24099.1 - 0.055 12.7 0.0 0.072 12.3 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 CRK24099.1 - 0.1 11.8 0.1 0.12 11.6 0.1 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Phage_GPL PF05926.11 CRK24100.1 - 0.0035 17.3 0.1 0.0072 16.3 0.1 1.5 1 0 0 1 1 1 1 Phage head completion protein (GPL) Pex14_N PF04695.13 CRK24100.1 - 0.067 13.8 1.3 0.16 12.6 1.3 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Glyco_hydro_11 PF00457.17 CRK24101.1 - 1.6e-78 262.4 15.7 1.8e-78 262.2 15.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Glyco_hydro_11 PF00457.17 CRK24102.1 - 8e-57 191.7 9.6 9.4e-57 191.5 9.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 tRNA-synt_1e PF01406.19 CRK24103.1 - 3.8e-111 371.3 0.1 6e-111 370.6 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 CRK24103.1 - 0.0001 21.2 0.2 0.24 10.1 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) DALR_2 PF09190.11 CRK24103.1 - 0.011 16.2 2.3 0.016 15.7 0.0 2.5 2 0 0 2 2 2 0 DALR domain GCD14 PF08704.10 CRK24104.1 - 2e-65 220.9 0.0 2.7e-42 145.2 0.0 3.3 2 1 1 3 3 3 3 tRNA methyltransferase complex GCD14 subunit DUF2057 PF09829.9 CRK24104.1 - 0.085 13.0 4.9 3.5 7.7 0.4 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) FIVAR PF07554.13 CRK24104.1 - 0.45 11.3 10.3 6.3 7.6 1.4 2.9 2 2 0 2 2 2 0 FIVAR domain BNIP3 PF06553.12 CRK24106.1 - 0.068 12.8 0.7 0.16 11.6 0.0 1.9 2 0 0 2 2 2 0 BNIP3 ADH_zinc_N_2 PF13602.6 CRK24109.1 - 1.3e-27 97.5 0.0 2e-27 96.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 CRK24109.1 - 2.4e-15 56.7 0.0 4.8e-15 55.7 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CRK24109.1 - 1.4e-08 34.6 0.5 3.5e-07 30.1 0.0 2.8 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain Sugar_tr PF00083.24 CRK24110.1 - 7.1e-107 358.1 16.9 1.2e-106 357.3 16.9 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK24110.1 - 9.9e-21 74.0 33.7 1.6e-15 56.9 6.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ring_hydroxyl_A PF00848.19 CRK24112.1 - 1.6e-19 70.7 4.8 7e-11 42.5 3.1 2.2 1 1 1 2 2 2 2 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 CRK24112.1 - 2.1e-15 56.4 0.0 4.2e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain DAO PF01266.24 CRK24113.1 - 2.1e-28 100.0 0.9 4.3e-28 98.9 0.9 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Zn_clus PF00172.18 CRK24113.1 - 1.4e-08 34.7 11.1 3.1e-08 33.6 11.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 CRK24113.1 - 3.9e-07 29.4 0.8 6.7e-07 28.6 0.8 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain NAD_binding_9 PF13454.6 CRK24113.1 - 6.5e-07 29.5 0.2 0.047 13.7 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 CRK24113.1 - 0.0058 16.8 0.0 0.016 15.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 CRK24113.1 - 0.022 13.6 0.0 0.2 10.4 0.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox_2 PF07992.14 CRK24113.1 - 0.046 12.9 0.0 1.9 7.7 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CRK24113.1 - 0.18 11.0 0.0 3.3 6.9 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 CRK24113.1 - 0.19 12.2 0.0 0.39 11.2 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Fungal_trans PF04082.18 CRK24114.1 - 0.00046 19.3 0.3 0.0018 17.4 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK24114.1 - 0.0019 18.3 4.6 0.0033 17.5 4.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aft1_HRA PF11786.8 CRK24114.1 - 0.052 13.9 0.5 21 5.5 0.0 2.7 2 0 0 2 2 2 0 Aft1 HRA domain DUF3328 PF11807.8 CRK24115.1 - 1.1e-21 77.7 1.1 4e-21 75.8 1.1 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Ribosomal_S19e PF01090.19 CRK24115.1 - 0.17 11.6 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S19e POR PF01558.18 CRK24116.1 - 0.1 12.6 0.3 4.6 7.3 0.1 2.2 1 1 1 2 2 2 0 Pyruvate ferredoxin/flavodoxin oxidoreductase Radial_spoke PF04712.12 CRK24116.1 - 0.11 11.4 1.2 0.17 10.8 1.2 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein DNA_pol_phi PF04931.13 CRK24116.1 - 9.9 4.1 12.1 14 3.6 12.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi SDH_alpha PF03313.15 CRK24117.1 - 1.8e-99 332.6 0.3 2.3e-99 332.3 0.3 1.1 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.15 CRK24117.1 - 2.9e-53 180.4 0.1 7.5e-53 179.1 0.0 1.8 2 0 0 2 2 2 1 Serine dehydratase beta chain p450 PF00067.22 CRK24118.1 - 3e-60 204.3 0.0 3.9e-60 203.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ABC_membrane PF00664.23 CRK24119.1 - 8.3e-82 274.9 35.6 7.6e-45 153.7 17.7 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CRK24119.1 - 1.5e-68 229.6 0.0 1.7e-33 116.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CRK24119.1 - 9.7e-15 54.6 1.0 9.9e-06 25.1 0.4 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CRK24119.1 - 9.3e-09 34.9 0.4 0.0021 17.8 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 CRK24119.1 - 3.1e-08 34.0 0.3 0.012 15.8 0.0 3.7 2 2 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 CRK24119.1 - 1.1e-07 31.9 0.0 0.021 14.7 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 CRK24119.1 - 2.1e-07 31.5 3.0 0.0019 18.6 0.2 3.0 2 1 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.9 CRK24119.1 - 9.3e-07 28.0 1.4 0.06 12.1 0.2 3.7 4 1 0 4 4 4 2 Predicted ATPase of the ABC class AAA_25 PF13481.6 CRK24119.1 - 5.8e-06 26.0 0.5 0.13 11.8 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_15 PF13175.6 CRK24119.1 - 6.9e-06 26.0 0.0 0.068 12.9 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.12 CRK24119.1 - 3.2e-05 23.3 0.1 0.29 10.4 0.0 2.9 3 0 0 3 3 3 2 Zeta toxin G-alpha PF00503.20 CRK24119.1 - 0.00029 20.1 0.0 0.7 9.0 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AAA_21 PF13304.6 CRK24119.1 - 0.00036 20.5 0.0 4.4 7.0 0.1 4.1 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 CRK24119.1 - 0.00038 20.2 3.4 1 9.1 0.0 3.8 4 0 0 4 4 4 2 AAA domain AAA_5 PF07728.14 CRK24119.1 - 0.00089 19.3 0.2 2.5 8.1 0.0 3.2 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 CRK24119.1 - 0.0051 16.9 0.0 1.7 8.8 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase Ploopntkinase3 PF18751.1 CRK24119.1 - 0.0052 16.7 0.1 1.8 8.4 0.0 2.6 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 AAA_23 PF13476.6 CRK24119.1 - 0.0055 17.2 1.6 0.72 10.3 0.1 2.6 3 0 0 3 3 2 1 AAA domain SbcCD_C PF13558.6 CRK24119.1 - 0.0067 16.6 3.1 7.2 6.9 0.1 4.0 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF815 PF05673.13 CRK24119.1 - 0.0083 15.3 0.0 1 8.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 CRK24119.1 - 0.0095 15.5 0.2 3.2 7.2 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_33 PF13671.6 CRK24119.1 - 0.016 15.3 0.0 8.5 6.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 CRK24119.1 - 0.024 14.4 0.4 7.8 6.2 0.1 3.1 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family Rad17 PF03215.15 CRK24119.1 - 0.038 13.9 0.0 0.72 9.8 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain APS_kinase PF01583.20 CRK24119.1 - 0.042 13.8 0.0 2.1 8.2 0.0 2.8 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_28 PF13521.6 CRK24119.1 - 0.043 14.1 0.9 0.8 9.9 0.1 2.6 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 CRK24119.1 - 0.047 12.9 0.0 2.8 7.1 0.0 2.5 2 0 0 2 2 2 0 KAP family P-loop domain AAA_18 PF13238.6 CRK24119.1 - 0.065 13.8 0.1 19 5.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 CRK24119.1 - 0.069 12.9 0.1 12 5.5 0.1 2.4 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 CRK24119.1 - 0.084 12.0 1.1 2.6 7.2 0.1 2.3 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.22 CRK24119.1 - 0.096 13.1 0.2 7.3 7.0 0.0 2.6 2 0 0 2 2 2 0 RNA helicase DUF87 PF01935.17 CRK24119.1 - 0.13 12.3 4.0 0.95 9.5 0.1 2.8 3 0 0 3 3 3 0 Helicase HerA, central domain NACHT PF05729.12 CRK24119.1 - 0.18 11.7 0.6 23 4.9 0.0 2.5 2 0 0 2 2 2 0 NACHT domain AAA PF00004.29 CRK24119.1 - 0.31 11.5 1.9 1.2e+02 3.1 0.1 4.0 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.22 CRK24119.1 - 1.2 8.8 6.1 9.3 5.8 0.1 2.7 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain Porphobil_deam PF01379.20 CRK24121.1 - 1.2e-74 250.3 0.0 1.4e-74 250.0 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 CRK24121.1 - 7.6e-17 61.5 0.0 1.3e-16 60.7 0.0 1.4 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain GCV_H PF01597.19 CRK24122.1 - 2e-35 121.4 0.6 2.4e-35 121.1 0.6 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 CRK24122.1 - 0.0019 18.0 0.3 0.0036 17.1 0.3 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme RnfC_N PF13375.6 CRK24122.1 - 0.025 14.5 0.1 0.035 14.1 0.1 1.3 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain DUF2118 PF09891.9 CRK24122.1 - 0.099 12.6 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) DUF2686 PF10887.8 CRK24122.1 - 0.16 10.9 0.0 0.21 10.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2686) Ras PF00071.22 CRK24123.1 - 1.8e-31 108.9 0.1 2.4e-31 108.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CRK24123.1 - 5.4e-24 84.7 0.1 9.7e-24 83.9 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CRK24123.1 - 1.7e-06 27.6 0.0 2.2e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CRK24123.1 - 0.00028 20.3 0.1 0.00038 19.9 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 CRK24123.1 - 0.0043 15.9 1.5 0.2 10.5 0.0 2.4 1 1 1 2 2 2 2 Dynein light intermediate chain (DLIC) TIP120 PF08623.10 CRK24125.1 - 2.1e-68 229.4 0.0 1.5e-66 223.3 0.0 3.5 3 0 0 3 3 3 1 TATA-binding protein interacting (TIP20) Adaptin_binding PF10199.9 CRK24125.1 - 2.1e-12 47.7 1.8 2.1e-12 47.7 1.8 2.3 2 1 0 2 2 1 1 Alpha and gamma adaptin binding protein p34 Adaptin_N PF01602.20 CRK24125.1 - 2.4e-10 39.6 5.4 1.9e-05 23.4 0.0 5.6 5 3 0 6 6 6 3 Adaptin N terminal region HEAT_2 PF13646.6 CRK24125.1 - 1.4e-07 31.8 16.0 0.019 15.3 0.2 8.5 7 1 1 8 8 8 2 HEAT repeats HEAT PF02985.22 CRK24125.1 - 3.6e-06 26.8 12.8 0.45 10.9 0.1 8.4 9 0 0 9 9 8 2 HEAT repeat RTP1_C1 PF10363.9 CRK24125.1 - 9.9e-06 25.7 3.4 0.12 12.6 0.0 4.2 4 0 0 4 4 4 2 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 CRK24125.1 - 0.00025 21.5 8.1 14 6.3 0.0 8.2 7 0 0 7 7 7 1 HEAT-like repeat U3snoRNP10 PF12397.8 CRK24125.1 - 0.0053 17.1 1.1 0.5 10.7 0.4 3.2 3 0 0 3 3 3 1 U3 small nucleolar RNA-associated protein 10 ParcG PF10274.9 CRK24125.1 - 0.083 13.0 2.0 19 5.3 0.0 4.0 4 0 0 4 4 4 0 Parkin co-regulated protein DUF3361 PF11841.8 CRK24125.1 - 0.23 11.4 1.6 28 4.6 0.0 4.0 3 2 2 5 5 5 0 Domain of unknown function (DUF3361) RICTOR_N PF14664.6 CRK24125.1 - 0.36 9.8 1.8 20 4.0 0.0 3.0 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, N-term Ank_4 PF13637.6 CRK24126.1 - 1.6e-42 143.4 11.2 1.4e-09 38.3 0.5 9.8 4 3 7 11 11 11 10 Ankyrin repeats (many copies) Ank_2 PF12796.7 CRK24126.1 - 3.5e-42 142.9 7.1 2e-12 47.5 0.1 5.8 4 2 2 6 6 6 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CRK24126.1 - 3.6e-40 131.3 7.8 3.3e-06 27.0 0.0 11.4 11 0 0 11 11 11 9 Ankyrin repeat Ank_5 PF13857.6 CRK24126.1 - 3.2e-32 110.2 15.1 6.2e-08 32.8 0.7 8.6 7 1 3 10 10 10 8 Ankyrin repeats (many copies) Ank PF00023.30 CRK24126.1 - 2.6e-23 81.4 23.3 0.0014 19.0 0.2 10.8 11 0 0 11 11 11 6 Ankyrin repeat DEC-1_N PF04625.13 CRK24126.1 - 4.3 6.2 13.2 0.035 13.1 2.9 2.2 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region PhoLip_ATPase_C PF16212.5 CRK24127.1 - 2.1e-08 34.2 2.2 2.4e-08 34.0 2.2 1.0 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal HemY_N PF07219.13 CRK24127.1 - 0.049 13.8 0.6 0.049 13.8 0.6 2.1 2 1 1 3 3 3 0 HemY protein N-terminus PhoLip_ATPase_C PF16212.5 CRK24128.1 - 4.9e-75 252.5 18.1 1.1e-74 251.3 18.1 1.6 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CRK24128.1 - 2.4e-23 81.6 1.4 2.3e-22 78.5 0.0 2.8 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 CRK24128.1 - 6.4e-15 56.0 0.3 2e-11 44.6 0.3 3.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CRK24128.1 - 2e-14 53.4 0.0 6.1e-13 48.7 0.0 2.5 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 CRK24128.1 - 2.8e-13 49.8 0.0 7.7e-13 48.4 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CRK24128.1 - 0.0011 18.7 0.0 0.0049 16.6 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 CRK24128.1 - 0.15 12.2 0.0 0.49 10.5 0.0 1.8 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase PhoLip_ATPase_C PF16212.5 CRK24129.1 - 4.8e-63 213.2 9.0 4.8e-63 213.2 9.0 1.7 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CRK24129.1 - 1.3e-23 82.4 0.5 1.9e-22 78.7 0.0 2.5 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 CRK24129.1 - 9.9e-15 54.4 0.0 3.5e-13 49.4 0.0 2.5 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 CRK24129.1 - 5.4e-13 48.9 0.0 1.2e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 CRK24129.1 - 1.1e-11 45.5 0.1 2.5e-05 24.7 0.0 3.4 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CRK24129.1 - 0.0017 18.2 0.0 0.0042 16.9 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Homeodomain PF00046.29 CRK24131.1 - 1.8e-19 69.3 2.2 3.5e-19 68.4 2.2 1.5 1 0 0 1 1 1 1 Homeodomain AsmA_1 PF13109.6 CRK24131.1 - 0.0053 16.3 0.2 3.5 7.0 0.0 2.2 2 0 0 2 2 2 2 AsmA-like C-terminal region Homeobox_KN PF05920.11 CRK24131.1 - 0.0077 16.1 0.4 0.017 15.0 0.4 1.6 1 0 0 1 1 1 1 Homeobox KN domain CCER1 PF15482.6 CRK24131.1 - 0.01 15.8 2.1 4 7.3 0.2 2.7 2 0 0 2 2 2 0 Coiled-coil domain-containing glutamate-rich protein family 1 MIP-T3_C PF17749.1 CRK24131.1 - 0.083 12.9 2.1 0.14 12.1 2.1 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region DUF865 PF05906.11 CRK24131.1 - 0.16 11.8 19.6 0.75 9.6 0.6 4.7 4 0 0 4 4 4 0 Herpesvirus-7 repeat of unknown function (DUF865) DUF929 PF06053.11 CRK24131.1 - 0.72 9.1 3.7 16 4.7 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF929) Ndc1_Nup PF09531.10 CRK24131.1 - 1.3 7.6 2.8 2 7.0 2.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FAM163 PF15069.6 CRK24133.1 - 0.17 12.3 0.1 0.97 9.9 0.0 2.0 2 0 0 2 2 2 0 FAM163 family LapA_dom PF06305.11 CRK24133.1 - 0.22 11.4 0.1 0.45 10.4 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Phage_holin_2_3 PF16080.5 CRK24133.1 - 0.25 11.1 0.4 0.43 10.4 0.4 1.3 1 0 0 1 1 1 0 Bacteriophage holin family HP1 CD24 PF14984.6 CRK24133.1 - 0.72 10.1 3.7 1.3 9.3 3.7 1.4 1 0 0 1 1 1 0 CD24 protein EphA2_TM PF14575.6 CRK24133.1 - 0.96 10.4 0.0 0.96 10.4 0.0 2.7 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Ctr PF04145.15 CRK24133.1 - 1.1 9.9 3.6 32 5.1 0.0 2.2 2 0 0 2 2 2 0 Ctr copper transporter family Zip PF02535.22 CRK24133.1 - 2.1 7.5 6.0 5.4 6.1 5.5 1.8 2 0 0 2 2 2 0 ZIP Zinc transporter Phage_holin_2_4 PF16082.5 CRK24133.1 - 2.5 7.9 3.7 0.72 9.6 0.1 2.0 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like DUF4834 PF16118.5 CRK24133.1 - 5.3 8.1 6.7 84 4.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Menin PF05053.13 CRK24134.1 - 0.62 8.4 7.7 0.83 7.9 7.7 1.1 1 0 0 1 1 1 0 Menin MAP65_ASE1 PF03999.12 CRK24134.1 - 8.6 4.9 5.8 11 4.5 5.8 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) ETRAMP PF09716.10 CRK24135.1 - 0.82 9.8 3.3 1.6 8.8 3.3 1.5 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) RTA1 PF04479.13 CRK24155.1 - 2.9e-75 252.4 5.0 4.8e-75 251.7 5.0 1.3 1 0 0 1 1 1 1 RTA1 like protein Abhydrolase_1 PF00561.20 CRK24155.1 - 6.3e-24 85.0 0.1 1.4e-23 83.8 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 CRK24155.1 - 2.3e-21 75.2 0.0 4.2e-21 74.3 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 CRK24155.1 - 0.0001 21.7 0.1 0.0079 15.5 0.0 2.6 2 1 0 2 2 2 1 Serine aminopeptidase, S33 FSH1 PF03959.13 CRK24155.1 - 0.00055 19.7 0.1 0.31 10.7 0.0 2.2 2 0 0 2 2 2 2 Serine hydrolase (FSH1) SPC22 PF04573.12 CRK24155.1 - 4.3 6.8 6.5 0.46 9.9 1.5 1.9 2 0 0 2 2 2 0 Signal peptidase subunit Pet191_N PF10203.9 CRK24156.1 - 2.9e-28 97.9 4.6 4e-28 97.5 4.6 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 COBRA PF04833.15 CRK24156.1 - 0.016 15.1 0.4 0.023 14.6 0.4 1.2 1 0 0 1 1 1 0 COBRA-like protein PAN_3 PF08277.12 CRK24156.1 - 0.11 12.3 0.5 0.19 11.5 0.5 1.4 1 0 0 1 1 1 0 PAN-like domain Clusterin PF01093.17 CRK24156.1 - 0.11 11.5 1.8 0.13 11.2 1.8 1.2 1 0 0 1 1 1 0 Clusterin CX9C PF16860.5 CRK24156.1 - 0.29 11.2 8.7 0.45 10.6 1.1 2.8 1 1 2 3 3 3 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 CRK24156.1 - 0.29 11.2 5.1 1.9 8.6 0.7 2.5 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like RTA1 PF04479.13 CRK24157.1 - 3.1e-75 252.3 5.5 5e-75 251.6 5.5 1.3 1 0 0 1 1 1 1 RTA1 like protein Abhydrolase_1 PF00561.20 CRK24157.1 - 7.3e-24 84.8 0.1 1.7e-23 83.6 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 CRK24157.1 - 2.1e-21 75.2 0.0 5e-21 74.0 0.0 1.7 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 CRK24157.1 - 7.7e-05 22.1 0.0 0.0049 16.2 0.0 2.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 FSH1 PF03959.13 CRK24157.1 - 0.00065 19.4 0.1 0.35 10.5 0.0 2.3 2 0 0 2 2 2 2 Serine hydrolase (FSH1) SPC22 PF04573.12 CRK24157.1 - 0.16 11.4 1.5 0.55 9.7 1.5 1.9 1 0 0 1 1 1 0 Signal peptidase subunit PI-PLC-X PF00388.19 CRK24161.1 - 2.1e-114 377.6 0.0 3.4e-56 188.9 0.0 2.3 2 0 0 2 2 2 2 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 CRK24161.1 - 8.9e-11 42.1 0.4 0.00033 21.0 0.1 3.4 2 1 1 3 3 3 2 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 CRK24161.1 - 0.015 15.6 0.0 0.038 14.3 0.0 1.7 1 0 0 1 1 1 0 C2 domain Herpes_DNAp_acc PF04929.12 CRK24161.1 - 0.072 12.1 3.6 3 6.7 0.2 2.2 2 0 0 2 2 2 0 Herpes DNA replication accessory factor DUF1481 PF07356.12 CRK24161.1 - 0.16 11.7 0.1 25 4.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1481) CobN-Mg_chel PF02514.16 CRK24161.1 - 1.6 6.4 3.0 14 3.3 0.2 2.1 2 0 0 2 2 2 0 CobN/Magnesium Chelatase Lon_C PF05362.13 CRK24161.1 - 1.8 8.0 4.4 14 5.1 0.7 2.2 2 0 0 2 2 2 0 Lon protease (S16) C-terminal proteolytic domain Gmx_para_CXXCG PF09535.10 CRK24162.1 - 0.62 9.3 3.2 8.3 5.6 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (Gmx_para_CXXCG) Phosphodiest PF01663.22 CRK24164.1 - 2.2e-99 333.4 1.1 8.5e-93 311.8 0.3 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 CRK24164.1 - 0.049 13.0 0.1 4.3 6.6 0.0 2.2 1 1 0 2 2 2 0 Sulfatase SpoIIIAH PF12685.7 CRK24164.1 - 4.7 7.0 11.4 0.041 13.7 1.7 2.1 2 0 0 2 2 2 0 SpoIIIAH-like protein SNF2_N PF00176.23 CRK24166.1 - 1.2e-56 192.0 1.5 5.6e-56 189.7 1.5 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 CRK24166.1 - 9.1e-08 32.3 0.0 1.8e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_34 PF13872.6 CRK24166.1 - 1.1e-06 27.8 0.0 2.2e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 PFK PF00365.20 CRK24167.1 - 3e-116 387.7 0.2 1.1e-80 271.0 0.0 2.1 2 0 0 2 2 2 2 Phosphofructokinase PI3_PI4_kinase PF00454.27 CRK24169.1 - 1.3e-44 152.9 0.0 2.3e-44 152.1 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase UME PF08064.13 CRK24169.1 - 1.2e-30 105.4 0.4 1e-29 102.4 0.1 2.9 3 1 0 3 3 3 1 UME (NUC010) domain FATC PF02260.20 CRK24169.1 - 7.1e-15 54.5 1.5 1.5e-14 53.4 0.0 2.5 3 0 0 3 3 3 1 FATC domain FAT PF02259.23 CRK24169.1 - 1.4e-14 54.1 0.5 2.8e-14 53.1 0.5 1.4 1 0 0 1 1 1 1 FAT domain IFRD PF05004.13 CRK24169.1 - 0.051 12.7 4.5 4.7 6.2 0.0 4.0 5 0 0 5 5 5 0 Interferon-related developmental regulator (IFRD) TPR_19 PF14559.6 CRK24169.1 - 0.087 13.4 0.0 0.43 11.1 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Polysacc_deac_1 PF01522.21 CRK24170.1 - 3.7e-19 68.8 0.0 5.7e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase C2 PF00168.30 CRK24174.1 - 0.00057 20.1 0.0 0.00074 19.8 0.0 1.1 1 0 0 1 1 1 1 C2 domain Glyco_transf_15 PF01793.16 CRK24197.1 - 6e-70 236.1 1.2 7.7e-70 235.7 1.2 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Pkinase PF00069.25 CRK24199.1 - 3.2e-60 203.7 0.0 5.6e-60 202.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK24199.1 - 3.2e-35 121.7 0.0 5.7e-35 120.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.16 CRK24199.1 - 6.1e-20 71.1 15.3 4.7e-11 42.6 8.0 3.0 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.22 CRK24199.1 - 1e-19 70.2 31.8 6e-12 45.3 11.3 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 CRK24199.1 - 2.6e-14 53.6 1.0 1.1e-13 51.6 1.0 2.2 1 0 0 1 1 1 1 Protein kinase C terminal domain PAT1 PF09770.9 CRK24199.1 - 0.00017 20.0 15.8 0.00028 19.3 15.8 1.2 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 C2 PF00168.30 CRK24199.1 - 0.00023 21.4 0.0 0.00048 20.4 0.0 1.5 1 0 0 1 1 1 1 C2 domain Haspin_kinase PF12330.8 CRK24199.1 - 0.13 11.2 0.1 0.31 9.9 0.1 1.6 1 0 0 1 1 1 0 Haspin like kinase domain zf-RING_9 PF13901.6 CRK24199.1 - 0.74 9.8 22.9 0.66 9.9 8.1 2.5 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon She9_MDM33 PF05546.11 CRK24201.1 - 3.5e-79 265.2 6.6 4.5e-79 264.9 6.6 1.1 1 0 0 1 1 1 1 She9 / Mdm33 family DivIVA PF05103.13 CRK24201.1 - 0.05 13.7 1.2 0.39 10.8 0.0 2.3 2 0 0 2 2 2 0 DivIVA protein PsbH PF00737.20 CRK24201.1 - 0.18 11.6 0.5 0.37 10.6 0.5 1.4 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein ADIP PF11559.8 CRK24201.1 - 1.8 8.7 9.4 0.43 10.6 3.9 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding SOG2 PF10428.9 CRK24201.1 - 4.7 6.3 26.0 6.9 5.8 26.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein HAD PF12710.7 CRK24203.1 - 9.9e-21 75.0 0.0 1.3e-20 74.6 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CRK24203.1 - 0.00024 21.5 0.0 0.012 15.9 0.0 2.7 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 CRK24203.1 - 0.00056 19.5 0.0 0.0012 18.4 0.0 1.6 2 0 0 2 2 2 1 Pyrimidine 5'-nucleotidase (UMPH-1) Put_Phosphatase PF06888.12 CRK24203.1 - 0.021 14.2 0.0 0.31 10.4 0.0 2.0 2 0 0 2 2 2 0 Putative Phosphatase MFS_1 PF07690.16 CRK24205.1 - 3.4e-15 55.8 46.4 1.2e-10 40.9 25.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily eIF-1a PF01176.19 CRK24207.1 - 1.3e-20 72.9 0.0 1.9e-20 72.4 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 ALG3 PF05208.13 CRK24209.1 - 1.3e-27 97.2 0.9 1.6e-27 96.9 0.9 1.1 1 0 0 1 1 1 1 ALG3 protein DAO PF01266.24 CRK24209.1 - 1.4e-08 34.7 0.0 1.9e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CRK24209.1 - 0.0017 18.6 0.0 0.0047 17.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CRK24209.1 - 0.0017 17.6 0.1 0.0024 17.1 0.1 1.2 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 CRK24209.1 - 0.032 13.3 0.0 0.041 13.0 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 CRK24209.1 - 0.052 14.1 0.1 0.09 13.3 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CRK24209.1 - 0.13 11.5 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF1560 PF07597.11 CRK24209.1 - 0.16 12.0 0.6 0.42 10.7 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1560) Mg_trans_NIPA PF05653.14 CRK24210.1 - 1.8e-69 234.1 23.9 2.3e-69 233.7 23.9 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 CRK24210.1 - 8e-05 22.8 5.5 8e-05 22.8 5.5 2.2 2 0 0 2 2 2 1 EamA-like transporter family CrgA PF06781.12 CRK24210.1 - 1.4 9.0 5.4 5.4 7.1 0.4 3.0 2 0 0 2 2 2 0 Cell division protein CrgA FTR1 PF03239.14 CRK24211.1 - 1.7e-46 158.8 7.7 2.1e-46 158.5 7.7 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family DUF4133 PF13571.6 CRK24211.1 - 0.26 11.7 3.5 10 6.6 1.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4133) FTR1 PF03239.14 CRK24212.1 - 1.1e-95 320.4 17.8 2.1e-76 257.0 10.8 2.0 2 0 0 2 2 2 2 Iron permease FTR1 family DUF4307 PF14155.6 CRK24212.1 - 4.8 7.1 10.0 11 6.0 0.2 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4307) Cu-oxidase_3 PF07732.15 CRK24213.1 - 3.7e-42 143.1 3.5 6e-38 129.5 1.0 2.7 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 CRK24213.1 - 5e-35 121.0 0.1 5.5e-33 114.3 0.0 2.3 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 CRK24213.1 - 5.7e-34 116.8 8.4 2.4e-32 111.5 0.5 3.1 2 1 0 2 2 2 2 Multicopper oxidase Sod_Cu PF00080.20 CRK24213.1 - 0.23 11.6 0.6 0.5 10.5 0.1 1.8 2 0 0 2 2 2 0 Copper/zinc superoxide dismutase (SODC) Glyco_hydro_43 PF04616.14 CRK24214.1 - 1e-05 25.0 1.5 0.48 9.7 0.1 3.2 2 1 1 3 3 3 3 Glycosyl hydrolases family 43 MFS_1 PF07690.16 CRK24215.1 - 5.1e-38 130.9 25.4 2.4e-37 128.7 26.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Myb_DNA-bind_6 PF13921.6 CRK24216.1 - 1.2e-20 73.5 3.4 4.7e-11 42.8 0.2 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 CRK24216.1 - 6.5e-20 71.1 4.9 1.7e-11 44.1 0.2 2.9 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 CRK24216.1 - 0.0026 18.1 0.9 0.0096 16.3 0.1 2.4 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 CRK24216.1 - 0.079 13.0 0.4 19 5.4 0.1 3.0 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain NOA36 PF06524.12 CRK24216.1 - 0.39 10.0 6.5 1.5 8.0 6.5 2.0 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 CRK24217.1 - 1.4e-235 783.5 0.0 2.4e-235 782.7 0.0 1.6 1 1 0 1 1 1 1 CDC45-like protein Hemerythrin PF01814.23 CRK24217.1 - 8.9e-11 42.5 0.3 3.5e-10 40.6 0.3 2.0 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain CSRNP_N PF16019.5 CRK24217.1 - 1.4 8.8 4.6 2.2 8.2 2.2 2.2 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus SMN PF06003.12 CRK24217.1 - 4.8 6.4 11.4 4.7 6.4 0.6 2.8 3 0 0 3 3 3 0 Survival motor neuron protein (SMN) BUD22 PF09073.10 CRK24217.1 - 4.9 6.4 30.1 0.32 10.3 12.2 2.2 2 0 0 2 2 2 0 BUD22 Zn_clus PF00172.18 CRK24218.1 - 1.6e-09 37.7 12.5 2.7e-09 37.0 12.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AT_hook PF02178.19 CRK24218.1 - 0.038 13.8 5.8 0.14 12.1 5.8 2.0 1 0 0 1 1 1 0 AT hook motif ABC2_membrane PF01061.24 CRK24219.1 - 3.9e-60 202.9 48.3 8.8e-26 90.6 6.7 3.6 3 1 1 4 4 3 3 ABC-2 type transporter ABC_tran PF00005.27 CRK24219.1 - 2.1e-48 164.3 0.0 8.7e-23 81.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter Peptidase_M20 PF01546.28 CRK24219.1 - 3.4e-28 98.8 0.0 6.6e-28 97.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CRK24219.1 - 2.5e-13 49.9 0.0 7.1e-13 48.4 0.0 1.9 1 0 0 1 1 1 1 Peptidase dimerisation domain AAA_21 PF13304.6 CRK24219.1 - 1.3e-10 41.6 15.7 0.011 15.6 0.0 5.3 4 1 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 CRK24219.1 - 2.1e-08 34.3 0.3 0.0069 16.3 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 CRK24219.1 - 5.2e-08 32.5 2.1 0.0085 15.8 0.3 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 CRK24219.1 - 6e-08 33.0 0.1 0.021 15.1 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.6 CRK24219.1 - 9.1e-08 32.8 1.4 0.0024 18.4 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CRK24219.1 - 1.2e-07 32.3 0.2 0.026 14.9 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 CRK24219.1 - 1.9e-07 30.8 1.4 0.063 12.7 0.3 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain T2SSE PF00437.20 CRK24219.1 - 2.8e-05 23.3 0.3 0.2 10.7 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_28 PF13521.6 CRK24219.1 - 3.8e-05 24.0 0.4 0.099 12.9 0.2 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 CRK24219.1 - 8e-05 23.0 0.1 0.11 12.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CRK24219.1 - 8.3e-05 22.4 0.1 0.41 10.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 CRK24219.1 - 0.00012 22.1 0.0 0.74 9.7 0.0 2.5 2 0 0 2 2 2 2 NACHT domain PDR_CDR PF06422.12 CRK24219.1 - 0.00014 21.7 0.1 0.00039 20.2 0.1 1.7 1 0 0 1 1 1 1 CDR ABC transporter AAA_25 PF13481.6 CRK24219.1 - 0.00074 19.1 0.0 0.43 10.1 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_15 PF13175.6 CRK24219.1 - 0.00084 19.1 1.2 7.9 6.1 0.1 3.3 3 0 0 3 3 3 0 AAA ATPase domain AAA_18 PF13238.6 CRK24219.1 - 0.0012 19.4 0.0 1.9 9.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 CRK24219.1 - 0.0012 18.4 1.5 1 8.9 0.0 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 CRK24219.1 - 0.0015 18.3 0.0 0.8 9.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CRK24219.1 - 0.002 18.5 0.1 2.7 8.4 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_7 PF12775.7 CRK24219.1 - 0.0023 17.5 0.3 0.64 9.5 0.1 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region MMR_HSR1 PF01926.23 CRK24219.1 - 0.0032 17.6 1.2 1.2 9.3 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 CRK24219.1 - 0.0034 17.2 0.3 0.68 9.7 0.1 2.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.18 CRK24219.1 - 0.0064 15.9 1.4 0.85 8.9 0.2 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family Pox_A32 PF04665.12 CRK24219.1 - 0.0077 15.7 0.1 0.35 10.3 0.0 2.4 2 0 0 2 2 2 1 Poxvirus A32 protein Sigma54_activat PF00158.26 CRK24219.1 - 0.013 15.2 0.1 6.2 6.5 0.0 3.2 3 0 0 3 3 2 0 Sigma-54 interaction domain PduV-EutP PF10662.9 CRK24219.1 - 0.014 15.1 0.2 3 7.6 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PhoH PF02562.16 CRK24219.1 - 0.015 14.8 0.3 2 7.8 0.1 2.4 2 0 0 2 2 2 0 PhoH-like protein Roc PF08477.13 CRK24219.1 - 0.017 15.3 0.1 3.8 7.7 0.1 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Septin PF00735.18 CRK24219.1 - 0.021 14.1 0.3 0.67 9.2 0.1 2.2 2 0 0 2 2 2 0 Septin SbcCD_C PF13558.6 CRK24219.1 - 0.022 15.0 0.3 8.1 6.8 0.0 3.4 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.12 CRK24219.1 - 0.026 13.8 0.1 3 7.1 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.6 CRK24219.1 - 0.026 14.7 0.0 9.4 6.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 CRK24219.1 - 0.029 14.3 0.0 2.3 8.1 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_5 PF07728.14 CRK24219.1 - 0.031 14.3 0.1 10 6.1 0.0 3.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MobB PF03205.14 CRK24219.1 - 0.042 13.8 0.3 3.9 7.4 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_ATPase PF09818.9 CRK24219.1 - 0.046 12.5 0.5 8.6 5.0 0.2 3.0 3 0 0 3 3 3 0 Predicted ATPase of the ABC class IstB_IS21 PF01695.17 CRK24219.1 - 0.081 12.7 0.4 8.8 6.0 0.0 3.2 4 0 0 4 4 3 0 IstB-like ATP binding protein SRPRB PF09439.10 CRK24219.1 - 0.092 12.2 0.2 8.8 5.7 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit PRK PF00485.18 CRK24219.1 - 0.096 12.4 0.1 3.5 7.3 0.1 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA PF00004.29 CRK24219.1 - 0.1 13.0 0.1 9.5 6.7 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) G-alpha PF00503.20 CRK24219.1 - 0.11 11.6 0.0 13 4.9 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit AAA_11 PF13086.6 CRK24219.1 - 0.14 11.9 6.1 1.3 8.8 0.0 3.0 3 0 0 3 3 3 0 AAA domain DUF2075 PF09848.9 CRK24219.1 - 0.26 10.5 0.2 13 4.9 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PDR_assoc PF08370.11 CRK24219.1 - 1.4 8.8 3.6 0.9 9.3 0.5 2.4 2 0 0 2 2 1 0 Plant PDR ABC transporter associated TUDOR PF00567.24 CRK24220.1 - 0.0066 16.5 0.0 0.0077 16.2 0.0 1.1 1 0 0 1 1 1 1 Tudor domain Sulf_coat_C PF12193.8 CRK24220.1 - 0.23 11.6 0.0 0.33 11.1 0.0 1.2 1 0 0 1 1 1 0 Sulfolobus virus coat protein C terminal Sld5 PF05916.11 CRK24221.1 - 5.7e-09 36.4 0.0 5.7e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 GINS complex protein Annexin_like PF18411.1 CRK24221.1 - 0.057 13.7 0.0 0.063 13.5 0.0 1.1 1 0 0 1 1 1 0 Annexin-like domain NAD_binding_1 PF00175.21 CRK24224.1 - 0.0034 18.0 0.0 0.0046 17.6 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DUF2738 PF10927.8 CRK24224.1 - 0.066 12.3 0.1 0.075 12.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2738) Palm_thioest PF02089.15 CRK24227.1 - 6.1e-27 95.0 0.0 6.4e-27 94.9 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF915 PF06028.11 CRK24227.1 - 0.029 13.7 0.0 0.03 13.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Protoglobin PF11563.8 CRK24236.1 - 5.8e-56 188.8 0.1 7.6e-56 188.4 0.1 1.2 1 0 0 1 1 1 1 Protoglobin WSC PF01822.19 CRK24236.1 - 0.00097 19.3 0.0 0.002 18.3 0.0 1.5 1 0 0 1 1 1 1 WSC domain Cas1_AcylT PF07779.12 CRK24240.1 - 1.9e-115 386.5 11.4 3.4e-115 385.7 11.4 1.4 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p Zn_clus PF00172.18 CRK24240.1 - 3.6e-07 30.2 10.1 8.1e-07 29.1 10.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PC-Esterase PF13839.6 CRK24240.1 - 0.012 15.4 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Fungal_trans PF04082.18 CRK24240.1 - 0.03 13.3 0.2 0.068 12.2 0.2 1.6 1 1 0 1 1 1 0 Fungal specific transcription factor domain HpcH_HpaI PF03328.14 CRK24243.1 - 1.4e-20 73.4 0.0 2.2e-20 72.8 0.0 1.3 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PK PF00224.21 CRK24243.1 - 0.11 11.4 0.1 0.17 10.7 0.1 1.3 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain Fungal_trans PF04082.18 CRK24243.1 - 0.14 11.1 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain Glyco_hydro_61 PF03443.14 CRK24244.1 - 1e-56 192.2 0.2 1.5e-56 191.6 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 adh_short_C2 PF13561.6 CRK24244.1 - 6.2e-42 143.7 0.2 1.7e-38 132.5 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRK24244.1 - 1.6e-35 122.3 0.4 3.8e-29 101.6 0.0 2.2 1 1 1 2 2 2 2 short chain dehydrogenase CBM_1 PF00734.18 CRK24244.1 - 2.3e-08 33.8 8.9 2.3e-08 33.8 8.9 2.5 2 0 0 2 2 2 1 Fungal cellulose binding domain KR PF08659.10 CRK24244.1 - 1.1e-06 28.7 0.0 0.0013 18.7 0.0 2.2 1 1 1 2 2 2 2 KR domain Methyltransf_16 PF10294.9 CRK24247.1 - 8.2e-29 100.5 0.0 1.3e-28 99.9 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase dCMP_cyt_deam_1 PF00383.23 CRK24250.1 - 2e-07 30.8 0.0 3e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CRK24250.1 - 1.2e-06 28.3 0.0 1.9e-06 27.6 0.0 1.3 1 1 0 1 1 1 1 MafB19-like deaminase Prok-JAB PF14464.6 CRK24250.1 - 0.15 11.8 0.1 0.28 11.0 0.1 1.5 1 0 0 1 1 1 0 Prokaryotic homologs of the JAB domain MFS_1 PF07690.16 CRK24254.1 - 2e-21 76.3 29.8 2e-21 76.3 29.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily FAM176 PF14851.6 CRK24254.1 - 0.054 13.2 0.0 0.26 10.9 0.0 2.0 2 0 0 2 2 2 0 FAM176 family DUF4212 PF13937.6 CRK24254.1 - 0.075 13.4 2.3 3.5 8.1 1.0 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4212) GWT1 PF06423.12 CRK24254.1 - 0.66 10.1 9.0 2 8.5 0.4 3.4 2 1 1 3 3 3 0 GWT1 Sugar_tr PF00083.24 CRK24254.1 - 0.96 8.2 38.2 9.6 4.9 38.2 2.6 1 1 0 1 1 1 0 Sugar (and other) transporter Glyco_hydro_12 PF01670.16 CRK24256.1 - 2.2e-41 142.2 5.9 2.7e-41 141.9 5.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 CBM_1 PF00734.18 CRK24256.1 - 1.5e-10 40.9 19.5 1.5e-10 40.9 19.5 2.7 3 0 0 3 3 3 1 Fungal cellulose binding domain Toxin_7 PF05980.12 CRK24256.1 - 0.064 13.5 9.2 0.15 12.3 9.2 1.7 1 0 0 1 1 1 0 Toxin 7 Haem_degrading PF03928.14 CRK24256.1 - 0.069 13.2 0.1 0.12 12.5 0.1 1.4 1 0 0 1 1 1 0 Haem-degrading PBP PF01161.20 CRK24258.1 - 4.3e-17 62.7 0.1 6.4e-17 62.1 0.1 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Methyltransf_23 PF13489.6 CRK24262.1 - 2.6e-34 118.4 0.0 3.5e-34 118.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK24262.1 - 4.3e-12 46.6 0.0 9.3e-12 45.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CRK24262.1 - 3.3e-11 43.7 0.0 5.6e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK24262.1 - 8.4e-11 41.9 0.0 2.4e-10 40.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK24262.1 - 5.6e-09 36.6 0.0 1.2e-08 35.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 CRK24262.1 - 0.0014 18.2 0.0 0.0022 17.6 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_2 PF00891.18 CRK24262.1 - 0.005 16.2 0.0 0.008 15.5 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Ubie_methyltran PF01209.18 CRK24262.1 - 0.013 14.8 0.0 0.04 13.3 0.0 1.6 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 CRK24262.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 CRK24262.1 - 0.14 11.7 0.0 1.1 8.7 0.0 2.0 2 0 0 2 2 2 0 Putative methyltransferase ABC_tran PF00005.27 CRK24271.1 - 1.1e-09 38.9 0.0 1.1e-09 38.9 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_28 PF13521.6 CRK24271.1 - 0.00018 21.8 0.0 0.00022 21.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.6 CRK24271.1 - 0.00056 19.8 0.0 0.00056 19.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CRK24271.1 - 0.001 19.6 0.6 0.0022 18.5 0.2 1.6 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 CRK24271.1 - 0.0015 19.0 0.0 0.0018 18.7 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 CRK24271.1 - 0.0021 17.7 0.0 0.003 17.3 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain NACHT PF05729.12 CRK24271.1 - 0.0096 15.9 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_15 PF13175.6 CRK24271.1 - 0.012 15.3 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 CRK24271.1 - 0.02 14.9 0.0 0.023 14.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CRK24271.1 - 0.028 14.8 0.1 0.066 13.6 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain SMC_N PF02463.19 CRK24271.1 - 0.036 13.5 0.0 0.064 12.7 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 CRK24271.1 - 0.038 14.5 0.0 0.046 14.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CRK24271.1 - 0.049 13.9 0.0 0.058 13.7 0.0 1.2 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CRK24271.1 - 0.055 13.9 0.0 0.087 13.2 0.0 1.3 1 0 0 1 1 1 0 RNA helicase AAA_27 PF13514.6 CRK24271.1 - 0.057 13.0 0.0 0.07 12.7 0.0 1.4 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 CRK24271.1 - 0.077 13.1 0.0 0.18 11.9 0.0 1.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_14 PF13173.6 CRK24271.1 - 0.078 13.0 0.0 0.1 12.7 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.6 CRK24271.1 - 0.078 13.4 0.0 0.2 12.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CRK24271.1 - 0.091 12.9 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 CRK24271.1 - 0.11 12.4 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase DUF815 PF05673.13 CRK24271.1 - 0.13 11.4 0.0 0.27 10.4 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Viral_helicase1 PF01443.18 CRK24271.1 - 0.16 11.7 0.0 0.16 11.7 0.0 1.1 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 CRK24271.1 - 0.18 11.0 0.0 0.51 9.5 0.0 1.6 1 1 0 2 2 2 0 NB-ARC domain TUDOR PF00567.24 CRK24274.1 - 2.1e-07 31.0 0.0 3.5e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Tudor domain SNase PF00565.17 CRK24274.1 - 0.00055 20.4 0.0 0.00077 19.9 0.0 1.3 1 0 0 1 1 1 1 Staphylococcal nuclease homologue CAF1 PF04857.20 CRK24276.1 - 0.052 12.7 0.0 0.062 12.5 0.0 1.1 1 0 0 1 1 1 0 CAF1 family ribonuclease MCM PF00493.23 CRK24279.1 - 2.5e-14 52.9 0.0 3.3e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 MCM P-loop domain RPAP1_N PF08621.10 CRK24279.1 - 0.16 11.7 0.3 0.37 10.6 0.3 1.6 1 0 0 1 1 1 0 RPAP1-like, N-terminal Multi-haem_cyto PF13447.6 CRK24279.1 - 0.17 11.1 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Seven times multi-haem cytochrome CxxCH NmrA PF05368.13 CRK24283.1 - 4.7e-52 176.9 0.0 5.3e-52 176.7 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 CRK24283.1 - 1.5e-07 31.5 0.1 8e-06 25.9 0.1 2.1 1 1 0 1 1 1 1 NAD(P)H-binding HEPN_RnaseLS PF18869.1 CRK24283.1 - 0.093 12.9 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 RnaseLS-like HEPN PMC2NT PF08066.12 CRK24284.1 - 7e-16 58.7 0.0 9.7e-16 58.2 0.0 1.2 1 0 0 1 1 1 1 PMC2NT (NUC016) domain DUF3895 PF13034.6 CRK24284.1 - 0.077 13.0 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3895) SurE PF01975.17 CRK24287.1 - 7.8e-25 87.8 0.0 1e-24 87.4 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE GH131_N PF18271.1 CRK24288.1 - 5e-77 259.0 0.0 6.4e-77 258.7 0.0 1.1 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain YbjQ_1 PF01906.17 CRK24288.1 - 3.8e-27 95.0 0.2 6.7e-27 94.2 0.2 1.4 1 0 0 1 1 1 1 Putative heavy-metal-binding PRA1 PF03208.19 CRK24290.1 - 1.9e-26 92.4 1.6 2.9e-26 91.8 1.6 1.2 1 0 0 1 1 1 1 PRA1 family protein Renin_r PF07850.14 CRK24290.1 - 0.32 11.6 1.8 0.34 11.5 0.0 1.9 2 0 0 2 2 2 0 Renin receptor-like protein ANAPC_CDC26 PF10471.9 CRK24290.1 - 9.8 7.1 11.9 0.25 12.2 3.7 2.7 2 1 1 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 DPPIV_N PF00930.21 CRK24291.1 - 9.2e-102 340.4 1.4 1.3e-101 340.0 1.4 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 CRK24291.1 - 1.4e-54 184.8 2.2 2.5e-54 183.9 2.2 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 CRK24291.1 - 2.2e-05 24.2 1.0 2.2e-05 24.2 1.0 2.6 3 1 1 4 4 4 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 CRK24291.1 - 0.015 15.9 2.2 0.015 15.9 2.2 3.5 2 2 1 3 3 3 0 Alpha/beta hydrolase family Med3 PF11593.8 CRK24291.1 - 0.62 9.2 15.6 1.1 8.4 15.6 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Clathrin PF00637.20 CRK24292.1 - 8.4e-179 586.6 33.8 6e-32 110.5 3.5 7.5 6 1 1 7 7 7 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 CRK24292.1 - 1.1e-33 113.8 0.2 7e-07 29.2 0.0 6.7 6 0 0 6 6 6 6 Clathrin propeller repeat Clathrin_H_link PF13838.6 CRK24292.1 - 1.1e-31 108.5 2.3 1.4e-31 108.1 0.1 2.5 3 0 0 3 3 3 1 Clathrin-H-link Coatomer_WDAD PF04053.14 CRK24292.1 - 9.6e-05 21.6 6.0 0.23 10.4 0.2 4.3 4 0 0 4 4 4 1 Coatomer WD associated region TPR_14 PF13428.6 CRK24292.1 - 0.00018 22.1 2.5 31 5.7 0.0 7.1 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_7 PF13176.6 CRK24292.1 - 0.001 18.9 3.0 11 6.3 0.1 6.0 6 0 0 6 6 5 1 Tetratricopeptide repeat PQQ_2 PF13360.6 CRK24292.1 - 0.0015 18.2 0.1 0.055 13.0 0.1 2.5 2 0 0 2 2 2 1 PQQ-like domain TPR_8 PF13181.6 CRK24292.1 - 0.0058 16.7 3.8 1.8 9.0 0.0 5.4 6 0 0 6 6 5 1 Tetratricopeptide repeat PPR PF01535.20 CRK24292.1 - 0.054 13.8 0.0 36 4.9 0.0 4.1 2 0 0 2 2 2 0 PPR repeat Clathrin-link PF09268.10 CRK24292.1 - 0.06 12.7 0.3 0.16 11.4 0.3 1.8 1 0 0 1 1 1 0 Clathrin, heavy-chain linker Vps39_1 PF10366.9 CRK24292.1 - 0.095 13.0 4.5 2.2 8.6 0.0 5.3 5 1 1 6 6 6 0 Vacuolar sorting protein 39 domain 1 TPR_1 PF00515.28 CRK24292.1 - 1.1 9.2 6.6 13 5.9 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF1640 PF07798.11 CRK24293.1 - 7.7e-54 182.4 7.9 1.2e-53 181.8 7.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) PseudoU_synth_1 PF01416.20 CRK24293.1 - 0.074 13.5 0.1 0.39 11.2 0.0 2.0 1 1 1 2 2 2 0 tRNA pseudouridine synthase GNAT_acetyltr_2 PF13718.6 CRK24293.1 - 0.13 11.6 0.6 0.3 10.4 0.1 1.7 1 1 1 2 2 2 0 GNAT acetyltransferase 2 cwf21 PF08312.12 CRK24293.1 - 0.16 12.2 2.4 0.47 10.6 2.4 1.8 1 1 0 1 1 1 0 cwf21 domain Cluap1 PF10234.9 CRK24293.1 - 0.25 10.7 7.2 0.37 10.1 7.2 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 Phytase PF02333.15 CRK24294.1 - 1.1e-67 228.6 0.1 3.9e-67 226.9 0.0 1.8 2 0 0 2 2 2 1 Phytase EGF_2 PF07974.13 CRK24294.1 - 1.8e-05 25.0 34.9 0.0013 19.0 15.4 2.5 2 0 0 2 2 2 2 EGF-like domain YcgL PF05166.13 CRK24294.1 - 0.23 11.8 0.6 7.2 7.0 0.3 2.6 2 0 0 2 2 2 0 YcgL domain EGF PF00008.27 CRK24294.1 - 2 8.8 28.3 0.74 10.2 7.5 2.6 2 0 0 2 2 2 0 EGF-like domain hEGF PF12661.7 CRK24294.1 - 8.5 7.2 29.1 0.37 11.5 8.2 2.9 3 0 0 3 3 3 0 Human growth factor-like EGF Methyltransf_23 PF13489.6 CRK24295.1 - 1.2e-05 25.3 0.0 1.8e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CRK24295.1 - 0.001 19.7 0.0 0.0026 18.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CRK24295.1 - 0.002 17.5 0.0 0.0035 16.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 CRK24295.1 - 0.012 16.3 0.0 0.025 15.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 CRK24295.1 - 0.039 14.7 0.1 0.14 12.9 0.1 2.0 1 1 0 1 1 1 0 Methyltransferase domain NAD_Gly3P_dh_N PF01210.23 CRK24296.1 - 1.2e-43 148.8 0.0 3.8e-43 147.2 0.0 1.8 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 CRK24296.1 - 5.2e-43 146.7 0.1 9.3e-43 145.9 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus K_oxygenase PF13434.6 CRK24296.1 - 0.15 11.1 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) hDGE_amylase PF14701.6 CRK24297.1 - 1.3e-177 591.4 0.0 1.6e-177 591.0 0.0 1.1 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 CRK24297.1 - 3.5e-119 398.2 0.2 6.8e-119 397.2 0.0 1.5 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 CRK24297.1 - 6.3e-80 268.5 0.0 1.3e-79 267.5 0.0 1.5 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 CRK24297.1 - 9.5e-30 102.6 0.0 2.1e-29 101.5 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.24 CRK24297.1 - 0.024 14.2 0.1 0.36 10.3 0.0 2.3 2 0 0 2 2 2 0 Alpha amylase, catalytic domain CFEM PF05730.11 CRK24298.1 - 0.024 14.7 3.3 0.048 13.7 3.3 1.5 1 0 0 1 1 1 0 CFEM domain Hum_adeno_E3A PF05393.11 CRK24298.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein BAR PF03114.18 CRK24324.1 - 1.7e-18 67.2 0.0 1.8e-18 67.0 0.0 1.0 1 0 0 1 1 1 1 BAR domain SURF4 PF02077.15 CRK24326.1 - 2.5e-33 115.8 2.8 2.7e-33 115.7 2.8 1.0 1 0 0 1 1 1 1 SURF4 family DUF2633 PF11119.8 CRK24326.1 - 1.8 8.5 4.3 3.1 7.8 4.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) DUF2236 PF09995.9 CRK24330.1 - 5e-36 125.0 7.9 5e-36 125.0 7.9 2.2 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2236) p450 PF00067.22 CRK24331.1 - 5.6e-38 130.9 0.0 7.6e-38 130.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pkinase_fungal PF17667.1 CRK24332.1 - 5.2e-137 457.0 0.0 6.5e-137 456.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 CRK24332.1 - 3e-05 23.5 0.0 6.4e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 CRK24332.1 - 0.026 14.5 0.1 0.09 12.7 0.0 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 CRK24332.1 - 0.18 11.1 0.1 1.5 8.0 0.0 2.0 2 0 0 2 2 2 0 Protein tyrosine kinase FA_hydroxylase PF04116.13 CRK24333.1 - 4.6e-15 56.1 12.5 4.4e-13 49.7 10.7 2.3 1 1 1 2 2 2 2 Fatty acid hydroxylase superfamily ERG4_ERG24 PF01222.17 CRK24334.1 - 8.4e-32 110.5 2.2 9.5e-32 110.3 2.2 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Peptidase_A22B PF04258.13 CRK24334.1 - 0.0084 15.7 0.1 0.018 14.6 0.1 1.5 1 1 0 1 1 1 1 Signal peptide peptidase Sigma70_r2 PF04542.14 CRK24334.1 - 0.072 12.9 0.3 0.66 9.8 0.0 2.2 2 0 0 2 2 2 0 Sigma-70 region 2 Skp1_POZ PF03931.15 CRK24335.1 - 0.0047 17.1 0.1 0.0066 16.6 0.1 1.5 1 1 0 1 1 1 1 Skp1 family, tetramerisation domain GFO_IDH_MocA PF01408.22 CRK24336.1 - 4.6e-31 108.1 0.4 7.1e-14 52.7 0.0 3.4 2 1 1 3 3 3 2 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 CRK24336.1 - 4.9e-18 65.2 0.2 1.7e-17 63.5 0.2 1.9 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain Response_reg PF00072.24 CRK24336.1 - 0.014 15.6 0.3 8.2 6.6 0.0 2.4 2 0 0 2 2 2 0 Response regulator receiver domain NAD_binding_3 PF03447.16 CRK24336.1 - 0.015 16.0 0.1 2.2 8.9 0.0 2.3 1 1 1 2 2 2 0 Homoserine dehydrogenase, NAD binding domain FAD_syn PF06574.12 CRK24336.1 - 0.024 14.5 0.0 10 6.0 0.0 2.4 2 0 0 2 2 2 0 FAD synthetase DUF1611_N PF17396.2 CRK24336.1 - 0.039 14.2 0.0 17 5.7 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1611_N) Rossmann-like domain DRTGG PF07085.12 CRK24336.1 - 0.054 13.3 0.1 13 5.6 0.0 2.6 2 0 0 2 2 2 0 DRTGG domain Wzy_C PF04932.15 CRK24336.1 - 0.094 12.3 0.0 16 5.1 0.0 2.6 2 0 0 2 2 2 0 O-Antigen ligase DUF3910 PF13049.6 CRK24336.1 - 0.13 12.5 0.0 27 5.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3910) MFS_1 PF07690.16 CRK24337.1 - 4.2e-32 111.4 31.2 4.2e-32 111.4 31.2 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Ion_trans_2 PF07885.16 CRK24337.1 - 1.7 8.7 9.1 0.4 10.7 3.2 3.0 2 0 0 2 2 2 0 Ion channel S_4TM PF18159.1 CRK24337.1 - 4.7 6.4 6.5 5.8 6.1 0.5 3.4 3 1 1 4 4 4 0 SMODS-associating 4TM effector domain Sugar_tr PF00083.24 CRK24338.1 - 3.2e-26 92.2 11.8 3.6e-26 92.0 11.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK24338.1 - 5e-08 32.3 9.2 5.7e-08 32.1 9.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Patched PF02460.18 CRK24338.1 - 0.24 9.4 1.5 0.32 9.0 1.5 1.1 1 0 0 1 1 1 0 Patched family LMBR1 PF04791.16 CRK24338.1 - 0.27 10.1 3.5 0.29 10.0 3.5 1.3 1 1 0 1 1 1 0 LMBR1-like membrane protein GTA_holin_3TM PF11351.8 CRK24338.1 - 0.37 11.3 2.4 0.79 10.3 2.4 1.6 1 0 0 1 1 1 0 Holin of 3TMs, for gene-transfer release IPTL-CTERM PF18203.1 CRK24338.1 - 4.8 7.2 6.6 3.5 7.6 1.4 2.4 2 0 0 2 2 2 0 IPTL-CTERM motif Zn_clus PF00172.18 CRK24339.1 - 2.2e-10 40.5 15.5 4.2e-10 39.6 15.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_23 PF13489.6 CRK24340.1 - 4.1e-19 69.0 0.0 9.1e-19 67.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain p450 PF00067.22 CRK24340.1 - 4.9e-18 65.1 0.0 1.2e-08 34.1 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 Methyltransf_25 PF13649.6 CRK24340.1 - 1.9e-11 44.5 0.0 5.3e-11 43.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK24340.1 - 3.2e-09 36.7 0.0 5.8e-08 32.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CRK24340.1 - 4.8e-09 36.7 0.0 1.5e-08 35.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK24340.1 - 4e-06 27.5 0.0 2e-05 25.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CRK24340.1 - 0.0027 17.3 0.0 0.0054 16.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 CRK24340.1 - 0.003 17.0 0.0 0.0051 16.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 CRK24340.1 - 0.005 16.2 0.0 0.055 12.8 0.0 2.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 CRK24340.1 - 0.014 14.7 0.0 0.043 13.1 0.0 1.7 2 0 0 2 2 2 0 O-methyltransferase domain FtsJ PF01728.19 CRK24340.1 - 0.13 12.3 0.0 0.37 10.9 0.0 1.7 2 0 0 2 2 2 0 FtsJ-like methyltransferase HET PF06985.11 CRK24341.1 - 3.9e-09 37.0 0.0 5.4e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Tmpp129 PF10272.9 CRK24341.1 - 0.024 14.0 0.9 0.032 13.5 0.9 1.1 1 0 0 1 1 1 0 Putative transmembrane protein precursor Cation_ATPase_C PF00689.21 CRK24346.1 - 1.7e-39 135.4 5.7 1.7e-39 135.4 5.7 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 CRK24346.1 - 2.7e-36 124.8 2.1 9.1e-36 123.1 2.1 2.0 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase PF13246.6 CRK24346.1 - 3.2e-20 72.0 0.0 8.1e-20 70.7 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CRK24346.1 - 4.9e-16 59.7 0.2 6.3e-15 56.0 0.2 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CRK24346.1 - 4e-10 39.2 0.2 2.9e-08 33.3 0.0 2.6 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CRK24346.1 - 3e-05 23.9 0.2 0.0002 21.2 0.6 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Phage_holin_3_6 PF07332.11 CRK24346.1 - 0.0027 17.7 2.4 0.13 12.3 0.6 3.3 3 0 0 3 3 3 1 Putative Actinobacterial Holin-X, holin superfamily III MAP17 PF15807.5 CRK24346.1 - 0.028 14.7 0.2 0.075 13.3 0.2 1.7 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Abhydrolase_9_N PF15420.6 CRK24346.1 - 0.14 12.1 4.3 3.8 7.5 0.1 3.2 3 0 0 3 3 3 0 Alpha/beta-hydrolase family N-terminus Glutaminase PF04960.15 CRK24347.1 - 9.1e-70 235.1 0.0 1.2e-69 234.7 0.0 1.1 1 0 0 1 1 1 1 Glutaminase Proteasome PF00227.26 CRK24369.1 - 3.3e-20 72.4 0.0 3.9e-20 72.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Arm PF00514.23 CRK24370.1 - 1.7e-16 59.6 8.9 7.3e-09 35.4 0.0 3.9 4 0 0 4 4 4 3 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 CRK24370.1 - 0.11 12.5 1.0 0.27 11.3 0.1 2.0 1 1 1 2 2 2 0 Spinocerebellar ataxia type 10 protein domain Phos_pyr_kin PF08543.12 CRK24372.1 - 0.00037 20.0 0.0 0.0004 19.8 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase RhlB PF12300.8 CRK24372.1 - 0.028 14.6 2.4 0.039 14.1 2.4 1.3 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB VirC2 PF07181.11 CRK24372.1 - 0.21 11.0 0.0 0.28 10.7 0.0 1.1 1 0 0 1 1 1 0 VirC2 protein ThiG PF05690.14 CRK24373.1 - 6.1e-08 32.3 1.0 9.3e-08 31.7 1.0 1.4 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG SOR_SNZ PF01680.17 CRK24373.1 - 0.00011 22.1 0.0 0.00016 21.5 0.0 1.3 1 0 0 1 1 1 1 SOR/SNZ family TetR_C_27 PF17935.1 CRK24373.1 - 0.00045 20.2 0.0 0.0018 18.3 0.0 1.8 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain His_biosynth PF00977.21 CRK24373.1 - 0.0082 15.6 0.1 0.025 14.0 0.0 1.8 2 0 0 2 2 2 1 Histidine biosynthesis protein NMO PF03060.15 CRK24373.1 - 0.011 15.2 1.4 0.011 15.1 1.4 1.1 1 0 0 1 1 1 0 Nitronate monooxygenase NanE PF04131.14 CRK24373.1 - 0.064 12.4 0.0 0.12 11.5 0.0 1.5 1 1 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase IGPS PF00218.21 CRK24373.1 - 0.17 11.0 0.0 0.46 9.6 0.0 1.7 1 1 1 2 2 2 0 Indole-3-glycerol phosphate synthase p450 PF00067.22 CRK24375.1 - 1.5e-40 139.4 0.0 2.5e-40 138.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 ABC2_membrane PF01061.24 CRK24376.1 - 1.2e-85 286.2 53.1 6.4e-45 153.2 20.8 2.5 2 0 0 2 2 2 2 ABC-2 type transporter PDR_CDR PF06422.12 CRK24376.1 - 1.5e-35 121.0 7.0 4.5e-32 109.8 0.2 3.2 3 0 0 3 3 2 2 CDR ABC transporter ABC_tran PF00005.27 CRK24376.1 - 6.5e-35 120.6 0.0 7.2e-16 59.0 0.0 2.9 3 0 0 3 3 3 2 ABC transporter ABC_trans_N PF14510.6 CRK24376.1 - 5.7e-14 52.5 0.0 2.2e-13 50.6 0.0 2.1 2 0 0 2 2 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 CRK24376.1 - 2.1e-06 28.2 0.1 0.0015 18.9 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 CRK24376.1 - 2.6e-06 27.1 0.4 8.4e-05 22.2 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CRK24376.1 - 6.4e-06 26.4 0.0 0.12 12.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 CRK24376.1 - 6.4e-05 22.9 0.1 0.0051 16.7 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 CRK24376.1 - 7e-05 22.8 0.0 1.4 8.6 0.0 3.3 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 CRK24376.1 - 0.00019 21.9 0.0 0.1 13.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CRK24376.1 - 0.00021 21.0 0.4 0.036 13.8 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.7 CRK24376.1 - 0.0011 18.1 6.8 0.0011 18.1 6.8 3.4 2 2 0 2 2 2 1 ABC-2 family transporter protein SMC_N PF02463.19 CRK24376.1 - 0.0017 17.8 0.0 2.8 7.3 0.0 3.7 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 CRK24376.1 - 0.0018 18.5 0.0 0.72 10.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 CRK24376.1 - 0.0024 17.8 0.1 2.3 8.1 0.1 2.6 2 0 0 2 2 2 2 NACHT domain AAA_17 PF13207.6 CRK24376.1 - 0.0053 17.2 0.1 2.9 8.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 CRK24376.1 - 0.0058 16.2 0.4 0.096 12.3 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 CRK24376.1 - 0.009 15.8 0.1 0.68 9.6 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 CRK24376.1 - 0.031 14.7 0.0 5.8 7.3 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PDR_assoc PF08370.11 CRK24376.1 - 0.055 13.2 0.6 1.9 8.3 0.0 3.3 3 0 0 3 3 3 0 Plant PDR ABC transporter associated AAA_23 PF13476.6 CRK24376.1 - 0.072 13.6 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 CRK24376.1 - 0.089 13.1 0.5 2.6 8.4 0.0 2.6 2 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 CRK24376.1 - 0.22 11.4 0.1 28 4.5 0.0 2.6 3 0 0 3 3 3 0 NTPase DUF1440 PF07274.12 CRK24376.1 - 2.8 8.3 7.2 4 7.8 0.9 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1440) Fungal_trans_2 PF11951.8 CRK24377.1 - 4.1e-11 42.3 0.0 2.1e-08 33.4 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain adh_short_C2 PF13561.6 CRK24378.1 - 8.8e-59 198.9 0.7 1.1e-58 198.6 0.7 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRK24378.1 - 1.7e-49 167.9 0.8 2.1e-49 167.6 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CRK24378.1 - 5.6e-13 49.2 0.5 8.5e-13 48.6 0.5 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 CRK24378.1 - 0.0074 15.7 0.0 0.018 14.5 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CRK24378.1 - 0.0076 15.7 0.5 0.019 14.4 0.5 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Cellulase PF00150.18 CRK24380.1 - 8.4e-22 77.9 2.8 1.2e-21 77.4 2.8 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 CRK24380.1 - 1.6e-13 50.4 14.8 5.2e-13 48.7 14.8 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain Glyco_hydro_42 PF02449.15 CRK24380.1 - 0.00062 19.2 0.3 0.001 18.5 0.3 1.3 1 0 0 1 1 1 1 Beta-galactosidase Glyco_hydro_2_C PF02836.17 CRK24380.1 - 0.032 13.4 0.0 0.049 12.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain AP_endonuc_2 PF01261.24 CRK24380.1 - 0.078 12.4 0.0 0.28 10.6 0.0 1.8 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel MGC-24 PF05283.11 CRK24380.1 - 0.43 11.0 9.7 1 9.8 9.7 1.6 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Abhydrolase_1 PF00561.20 CRK24381.1 - 3.7e-08 33.3 0.0 1.3e-07 31.5 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CRK24381.1 - 1.1e-06 28.1 0.0 3.3e-06 26.5 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CRK24381.1 - 2.3e-05 25.1 0.1 3.3e-05 24.6 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 CRK24381.1 - 0.038 14.1 0.0 0.095 12.8 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein Abhydrolase_2 PF02230.16 CRK24381.1 - 0.068 13.0 0.0 0.15 11.9 0.0 1.6 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase NMT_C PF02799.15 CRK24382.1 - 7.1e-84 280.5 0.0 1.2e-83 279.8 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 CRK24382.1 - 2.1e-62 209.7 0.4 6.4e-62 208.1 0.0 1.9 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain TFIIF_alpha PF05793.12 CRK24382.1 - 0.08 11.5 11.4 0.12 10.9 11.4 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PGA2 PF07543.12 CRK24382.1 - 0.099 12.6 8.4 0.21 11.6 8.4 1.5 1 0 0 1 1 1 0 Protein trafficking PGA2 LZ_Tnp_IS66 PF13007.7 CRK24382.1 - 0.36 11.6 4.3 1.1 10.1 4.3 1.8 1 0 0 1 1 1 0 Transposase C of IS166 homeodomain CDC45 PF02724.14 CRK24382.1 - 2.9 6.1 5.5 4.1 5.6 5.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Abhydrolase_1 PF00561.20 CRK24384.1 - 3.6e-11 43.2 0.5 5.2e-11 42.7 0.5 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CRK24384.1 - 1.5e-10 40.8 0.8 2.1e-09 37.0 0.3 2.1 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CRK24384.1 - 2.5e-10 41.3 4.9 5e-10 40.4 4.9 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 CRK24384.1 - 5.5e-05 23.1 0.4 8.3e-05 22.5 0.4 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 CRK24384.1 - 0.0072 16.1 0.1 0.19 11.5 0.0 2.1 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.18 CRK24384.1 - 0.0086 15.7 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Thioesterase PF00975.20 CRK24384.1 - 0.061 13.4 0.1 0.22 11.6 0.0 1.8 1 1 1 2 2 2 0 Thioesterase domain Peptidase_S9 PF00326.21 CRK24384.1 - 0.2 11.1 0.0 0.76 9.2 0.0 1.9 1 1 0 1 1 1 0 Prolyl oligopeptidase family HeLo PF14479.6 CRK24386.1 - 5e-09 36.3 1.2 1.4e-06 28.3 0.7 2.2 1 1 1 2 2 2 2 Prion-inhibition and propagation Pkinase_Tyr PF07714.17 CRK24386.1 - 0.0011 18.4 0.0 0.0024 17.2 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CRK24386.1 - 0.0014 18.1 0.0 0.0027 17.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 CRK24387.1 - 2.4e-23 82.8 0.0 4.6e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.7 CRK24387.1 - 3.4e-23 82.0 0.0 3.1e-05 24.5 0.0 6.5 3 2 4 7 7 7 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CRK24387.1 - 2.6e-20 72.2 4.3 0.015 15.6 0.0 7.5 6 2 2 8 8 8 5 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 CRK24387.1 - 5.4e-20 71.8 0.0 1.2e-19 70.6 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_4 PF13637.6 CRK24387.1 - 4.8e-18 65.3 0.4 0.0011 19.4 0.0 7.0 6 1 1 7 7 7 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CRK24387.1 - 7.1e-12 44.4 8.7 1.9 9.3 0.0 9.1 9 0 0 9 9 9 4 Ankyrin repeat Ank PF00023.30 CRK24387.1 - 2.2e-08 34.1 8.3 0.055 13.9 0.1 6.7 6 0 0 6 6 6 2 Ankyrin repeat Sel1 PF08238.12 CRK24387.1 - 0.0035 18.0 0.1 0.018 15.7 0.1 2.3 1 0 0 1 1 1 1 Sel1 repeat Kdo PF06293.14 CRK24387.1 - 0.054 12.8 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TLD PF07534.16 CRK24389.1 - 7.8e-27 94.2 0.0 1.5e-26 93.3 0.0 1.5 1 0 0 1 1 1 1 TLD DUF1773 PF08593.10 CRK24389.1 - 1.6e-07 32.2 0.4 1.6e-07 32.2 0.4 2.1 2 0 0 2 2 2 1 Domain of unknown function HIG_1_N PF04588.13 CRK24390.1 - 2.3e-21 75.8 3.8 2.4e-21 75.7 1.1 2.1 2 0 0 2 2 2 1 Hypoxia induced protein conserved region DUF1413 PF07205.11 CRK24390.1 - 0.048 13.7 0.1 0.12 12.4 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1413) DUF2514 PF10721.9 CRK24390.1 - 0.05 13.6 5.3 0.077 13.0 5.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) PALP PF00291.25 CRK24391.1 - 2.7e-77 260.1 0.5 3.4e-77 259.7 0.5 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 CRK24391.1 - 5.2e-41 138.3 0.0 1.1e-21 76.3 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase Ribosomal_L36 PF00444.18 CRK24392.1 - 7.3e-22 77.3 11.3 1e-21 76.8 11.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L36 Ribosomal_L35p PF01632.19 CRK24392.1 - 0.55 10.8 7.6 0.28 11.7 5.1 1.9 2 1 0 2 2 2 0 Ribosomal protein L35 FAD_binding_4 PF01565.23 CRK24393.1 - 5.1e-23 81.4 0.5 8.7e-23 80.6 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain Acetyltransf_1 PF00583.25 CRK24394.1 - 8.5e-10 38.9 0.0 1.1e-09 38.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CRK24394.1 - 0.00012 22.1 0.0 0.00015 21.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CRK24394.1 - 0.0002 21.3 0.0 0.00036 20.4 0.0 1.5 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 CRK24394.1 - 0.00057 20.3 0.0 0.00089 19.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 CRK24394.1 - 0.0072 17.0 0.0 0.012 16.3 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF2156 PF09924.9 CRK24394.1 - 0.13 11.2 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2156) Ferric_reduct PF01794.19 CRK24395.1 - 7.3e-24 84.3 16.8 7.3e-24 84.3 16.8 2.4 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 CRK24395.1 - 4.5e-10 39.6 0.7 1.5e-06 28.3 0.2 2.7 3 0 0 3 3 3 2 FAD-binding domain NAD_binding_6 PF08030.12 CRK24395.1 - 1.4e-07 31.7 0.0 0.0033 17.5 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain DUF4079 PF13301.6 CRK24395.1 - 0.19 11.9 11.2 3.6 7.7 5.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4079) DUF3094 PF11293.8 CRK24395.1 - 5.7 6.7 7.2 4.4 7.1 1.4 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) GFA PF04828.14 CRK24396.1 - 3.4e-11 43.3 1.4 3.8e-11 43.2 0.2 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme PTR2 PF00854.21 CRK24397.1 - 6.4e-77 259.0 11.0 6.4e-77 259.0 11.0 1.4 2 0 0 2 2 2 1 POT family Oxidored_FMN PF00724.20 CRK24398.1 - 1.1e-97 327.4 0.0 1.3e-97 327.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.24 CRK24398.1 - 0.067 12.6 0.1 2.6 7.4 0.0 2.3 1 1 1 2 2 2 0 Xylose isomerase-like TIM barrel Spt5-NGN PF03439.13 CRK24400.1 - 7.1e-22 77.1 0.3 9.2e-22 76.8 0.3 1.2 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.8 CRK24400.1 - 4.8e-06 27.5 0.2 1.3e-05 26.0 0.0 1.7 2 0 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal Peptidase_M15_2 PF05951.13 CRK24400.1 - 0.13 11.9 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF882) HSP70 PF00012.20 CRK24422.1 - 2.9e-45 154.6 0.3 3.2e-45 154.4 0.3 1.0 1 0 0 1 1 1 1 Hsp70 protein Ploopntkinase3 PF18751.1 CRK24422.1 - 0.058 13.3 0.0 0.065 13.1 0.0 1.1 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Ribosomal_L6e PF01159.19 CRK24427.1 - 5.8e-18 65.5 0.1 7.4e-18 65.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L6e FbpA PF05833.11 CRK24429.1 - 0.00058 18.7 2.8 0.00063 18.6 2.8 1.0 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) OmpH PF03938.14 CRK24429.1 - 0.0036 17.6 6.9 0.0046 17.3 6.9 1.1 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) Clathrin_lg_ch PF01086.17 CRK24429.1 - 0.0052 16.9 3.4 0.0066 16.5 3.4 1.0 1 0 0 1 1 1 1 Clathrin light chain FlgN PF05130.12 CRK24429.1 - 0.0067 17.0 3.5 0.0068 16.9 2.5 1.4 2 0 0 2 2 2 1 FlgN protein DUF1664 PF07889.12 CRK24429.1 - 0.029 14.4 1.2 0.035 14.1 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) AvrPtoB_bdg PF16847.5 CRK24429.1 - 0.055 14.0 0.1 0.084 13.4 0.1 1.4 1 0 0 1 1 1 0 Avirulence AvrPtoB, BAK1-binding domain SNARE PF05739.19 CRK24429.1 - 0.11 12.5 0.3 0.19 11.7 0.3 1.4 1 0 0 1 1 1 0 SNARE domain Lambda_Bor PF06291.11 CRK24429.1 - 0.19 11.8 0.1 0.26 11.3 0.1 1.2 1 0 0 1 1 1 0 Bor protein Ank_2 PF12796.7 CRK24431.1 - 6e-42 142.1 7.1 2.6e-12 47.2 0.1 5.9 4 2 2 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CRK24431.1 - 6.8e-41 138.1 12.6 1.5e-09 38.1 0.5 9.7 4 3 7 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 CRK24431.1 - 2.2e-39 128.9 8.2 3.8e-06 26.8 0.0 11.4 11 0 0 11 11 11 9 Ankyrin repeat Ank_5 PF13857.6 CRK24431.1 - 1.4e-31 108.1 14.7 7.2e-08 32.6 0.7 8.4 7 1 3 10 10 10 8 Ankyrin repeats (many copies) Ank PF00023.30 CRK24431.1 - 5.8e-23 80.3 24.0 0.0016 18.8 0.2 10.8 11 0 0 11 11 11 6 Ankyrin repeat PPE PF00823.19 CRK24431.1 - 0.031 14.4 3.0 0.11 12.6 3.0 1.8 1 1 0 1 1 1 0 PPE family MlrC_C PF07171.12 CRK24431.1 - 0.084 13.0 2.1 0.18 12.0 0.6 2.3 2 0 0 2 2 2 0 MlrC C-terminus Adaptin_binding PF10199.9 CRK24432.1 - 7.8e-14 52.3 5.3 2.7e-13 50.6 5.3 1.9 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 TIP120 PF08623.10 CRK24433.1 - 3.5e-69 231.9 0.0 1.1e-66 223.7 0.0 4.1 3 0 0 3 3 3 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.6 CRK24433.1 - 3.1e-10 40.3 20.0 0.008 16.6 0.1 9.4 6 3 3 9 9 9 2 HEAT repeats Adaptin_N PF01602.20 CRK24433.1 - 5.7e-08 31.8 10.0 0.00067 18.3 0.2 5.9 4 2 3 7 7 7 1 Adaptin N terminal region HEAT PF02985.22 CRK24433.1 - 1.9e-07 30.8 21.7 0.26 11.6 0.1 10.1 11 0 0 11 11 10 2 HEAT repeat HEAT_EZ PF13513.6 CRK24433.1 - 3.3e-06 27.5 14.0 2.2 8.9 0.0 9.9 10 0 0 10 10 9 1 HEAT-like repeat RTP1_C1 PF10363.9 CRK24433.1 - 3e-05 24.1 9.2 0.064 13.4 0.0 5.2 6 0 0 6 6 5 2 Required for nuclear transport of RNA pol II C-terminus 1 IFRD PF05004.13 CRK24433.1 - 6.5e-05 22.2 2.7 1.4 8.0 0.0 5.7 5 1 0 5 5 5 1 Interferon-related developmental regulator (IFRD) U3snoRNP10 PF12397.8 CRK24433.1 - 0.00092 19.5 1.1 0.32 11.4 0.4 3.5 3 0 0 3 3 3 1 U3 small nucleolar RNA-associated protein 10 CLASP_N PF12348.8 CRK24433.1 - 0.0036 16.9 1.1 14 5.2 0.0 5.2 5 1 1 6 6 6 0 CLASP N terminal ParcG PF10274.9 CRK24433.1 - 0.021 15.0 2.3 15 5.7 0.0 4.3 4 0 0 4 4 4 0 Parkin co-regulated protein RICTOR_N PF14664.6 CRK24433.1 - 0.12 11.4 2.5 10 5.0 0.0 3.3 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, N-term DUF3361 PF11841.8 CRK24433.1 - 0.36 10.7 4.6 16 5.4 0.0 4.4 4 2 1 5 5 5 0 Domain of unknown function (DUF3361) DUF5578 PF17741.1 CRK24433.1 - 0.4 10.1 6.0 1.8 7.9 0.0 3.7 4 0 0 4 4 4 0 Family of unknown function (DUF5578) Sigma70_ner PF04546.13 CRK24433.1 - 4.7 7.0 7.1 18 5.1 0.0 3.1 3 0 0 3 3 3 0 Sigma-70, non-essential region Ras PF00071.22 CRK24435.1 - 1.8e-31 108.9 0.1 2.4e-31 108.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CRK24435.1 - 5.4e-24 84.7 0.1 9.7e-24 83.9 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CRK24435.1 - 1.7e-06 27.6 0.0 2.2e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CRK24435.1 - 0.00028 20.3 0.1 0.00038 19.9 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 CRK24435.1 - 0.0043 15.9 1.5 0.2 10.5 0.0 2.4 1 1 1 2 2 2 2 Dynein light intermediate chain (DLIC) GCV_H PF01597.19 CRK24436.1 - 5.3e-35 120.0 0.5 6.3e-35 119.7 0.5 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 CRK24436.1 - 0.002 17.9 0.3 0.0036 17.1 0.3 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme RnfC_N PF13375.6 CRK24436.1 - 0.026 14.5 0.1 0.035 14.1 0.1 1.3 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain DUF2118 PF09891.9 CRK24436.1 - 0.1 12.6 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) DUF2686 PF10887.8 CRK24436.1 - 0.13 11.2 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2686) Porphobil_deam PF01379.20 CRK24437.1 - 1.6e-75 253.1 0.0 2e-75 252.8 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 CRK24437.1 - 2.7e-16 59.7 0.0 4.8e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain ABC_membrane PF00664.23 CRK24439.1 - 1.3e-81 274.2 35.2 7.6e-45 153.7 17.7 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CRK24439.1 - 1.5e-68 229.6 0.0 1.7e-33 116.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CRK24439.1 - 7.6e-15 54.9 0.7 1.9e-05 24.2 0.0 4.3 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CRK24439.1 - 9.3e-09 34.9 0.4 0.0021 17.8 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 CRK24439.1 - 1.6e-08 34.9 0.2 0.0066 16.7 0.0 3.7 2 2 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 CRK24439.1 - 1.1e-07 31.9 0.1 0.021 14.7 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 CRK24439.1 - 1.6e-07 31.9 2.3 0.0023 18.3 0.1 3.0 2 1 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.9 CRK24439.1 - 9.2e-07 28.0 1.4 0.06 12.1 0.2 3.7 4 1 0 4 4 4 2 Predicted ATPase of the ABC class AAA_25 PF13481.6 CRK24439.1 - 5.2e-06 26.2 0.4 0.13 11.8 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_15 PF13175.6 CRK24439.1 - 7e-06 26.0 0.0 0.069 12.9 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.12 CRK24439.1 - 3.1e-05 23.3 0.1 0.29 10.4 0.0 2.9 3 0 0 3 3 3 2 Zeta toxin G-alpha PF00503.20 CRK24439.1 - 0.00027 20.2 0.0 0.65 9.1 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AAA_30 PF13604.6 CRK24439.1 - 0.00029 20.6 3.1 0.97 9.1 0.0 3.8 4 0 0 4 4 4 2 AAA domain AAA_21 PF13304.6 CRK24439.1 - 0.00058 19.8 0.2 5 6.8 0.2 4.1 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_5 PF07728.14 CRK24439.1 - 0.00089 19.3 0.2 2.5 8.1 0.0 3.2 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) Ploopntkinase3 PF18751.1 CRK24439.1 - 0.0051 16.7 0.1 1.8 8.4 0.0 2.6 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 MMR_HSR1 PF01926.23 CRK24439.1 - 0.0052 16.8 0.0 1.7 8.8 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_23 PF13476.6 CRK24439.1 - 0.0055 17.2 1.6 0.72 10.3 0.1 2.6 3 0 0 3 3 2 1 AAA domain SbcCD_C PF13558.6 CRK24439.1 - 0.0066 16.7 3.0 7.2 6.9 0.1 4.0 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF815 PF05673.13 CRK24439.1 - 0.0085 15.3 0.0 1 8.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 CRK24439.1 - 0.0089 15.6 0.2 3.1 7.3 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_33 PF13671.6 CRK24439.1 - 0.016 15.4 0.0 8 6.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 CRK24439.1 - 0.024 14.4 0.4 7.8 6.2 0.1 3.1 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family KAP_NTPase PF07693.14 CRK24439.1 - 0.028 13.7 0.0 2.8 7.1 0.0 2.6 2 0 0 2 2 2 0 KAP family P-loop domain APS_kinase PF01583.20 CRK24439.1 - 0.036 13.9 0.0 1.7 8.5 0.0 2.7 2 0 0 2 2 2 0 Adenylylsulphate kinase Rad17 PF03215.15 CRK24439.1 - 0.038 13.9 0.0 0.72 9.8 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_28 PF13521.6 CRK24439.1 - 0.051 13.8 1.2 0.82 9.9 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 CRK24439.1 - 0.068 12.9 0.1 12 5.5 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 CRK24439.1 - 0.078 13.5 0.1 23 5.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 CRK24439.1 - 0.082 12.1 1.1 2.6 7.2 0.1 2.3 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.22 CRK24439.1 - 0.093 13.1 0.2 7.2 7.1 0.0 2.6 2 0 0 2 2 2 0 RNA helicase DUF87 PF01935.17 CRK24439.1 - 0.13 12.3 4.0 0.94 9.5 0.1 2.8 3 0 0 3 3 3 0 Helicase HerA, central domain NACHT PF05729.12 CRK24439.1 - 0.18 11.7 0.6 23 4.9 0.0 2.5 2 0 0 2 2 2 0 NACHT domain AAA PF00004.29 CRK24439.1 - 0.37 11.2 2.2 1.2e+02 3.1 0.1 4.0 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.22 CRK24439.1 - 1.2 8.7 6.1 9.3 5.8 0.1 2.7 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain Fungal_trans PF04082.18 CRK24440.1 - 1.5e-07 30.7 0.0 2.9e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK24440.1 - 0.0036 17.4 4.8 0.0069 16.5 4.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SDH_alpha PF03313.15 CRK24441.1 - 1.6e-99 332.8 0.2 2.1e-99 332.4 0.2 1.2 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.15 CRK24441.1 - 1.6e-53 181.2 0.1 4.2e-53 179.9 0.0 1.8 2 0 0 2 2 2 1 Serine dehydratase beta chain DUF4311 PF14188.6 CRK24442.1 - 0.2 11.4 0.0 0.31 10.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4311) DUF3328 PF11807.8 CRK24443.1 - 2.5e-20 73.2 4.5 2.2e-19 70.1 4.5 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Ribosomal_S19e PF01090.19 CRK24443.1 - 0.18 11.5 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S19e Zn_clus PF00172.18 CRK24445.1 - 3.1e-06 27.2 10.3 5e-06 26.5 10.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 CRK24445.1 - 0.00035 19.7 0.1 0.0016 17.5 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Aft1_HRA PF11786.8 CRK24445.1 - 0.042 14.2 0.3 20 5.6 0.0 2.7 2 0 0 2 2 2 0 Aft1 HRA domain GCV_T PF01571.21 CRK24446.1 - 1.1e-67 228.2 0.0 1.5e-67 227.7 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain DAO PF01266.24 CRK24446.1 - 4.6e-46 158.0 0.7 7.7e-46 157.3 0.7 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase GCV_T_C PF08669.11 CRK24446.1 - 2.2e-19 69.1 1.2 4.2e-19 68.2 0.2 2.1 2 0 0 2 2 2 1 Glycine cleavage T-protein C-terminal barrel domain FAO_M PF16350.5 CRK24446.1 - 6.7e-19 68.0 0.1 1.4e-18 66.9 0.1 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase central domain Pyr_redox_2 PF07992.14 CRK24446.1 - 5.2e-05 22.6 0.0 0.28 10.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CRK24446.1 - 0.00019 20.6 0.2 0.00064 18.9 0.2 1.9 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 CRK24446.1 - 0.00025 21.5 0.5 0.074 13.6 0.2 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SoxG PF04268.12 CRK24446.1 - 0.0015 18.7 0.0 0.02 15.1 0.0 2.2 1 1 1 2 2 2 1 Sarcosine oxidase, gamma subunit family TrkA_N PF02254.18 CRK24446.1 - 0.003 17.8 0.5 0.011 16.0 0.1 2.2 2 0 0 2 2 2 1 TrkA-N domain Trp_halogenase PF04820.14 CRK24446.1 - 0.01 14.7 0.2 0.23 10.2 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Shikimate_DH PF01488.20 CRK24446.1 - 0.012 15.7 0.1 0.022 14.8 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.21 CRK24446.1 - 0.021 14.2 0.1 0.036 13.4 0.1 1.3 1 0 0 1 1 1 0 ThiF family NAD_binding_9 PF13454.6 CRK24446.1 - 0.039 13.9 0.3 0.61 10.1 0.1 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 CRK24446.1 - 0.11 12.8 0.1 0.6 10.4 0.0 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Sacchrp_dh_NADP PF03435.18 CRK24446.1 - 0.11 12.7 0.2 0.47 10.7 0.2 2.1 2 0 0 2 2 1 0 Saccharopine dehydrogenase NADP binding domain FAD_binding_3 PF01494.19 CRK24446.1 - 0.14 11.4 0.5 12 5.0 0.4 2.2 2 0 0 2 2 2 0 FAD binding domain DD_K PF12121.8 CRK24446.1 - 0.46 10.6 2.4 1.3 9.2 2.4 1.8 1 0 0 1 1 1 0 Dermaseptin DAO PF01266.24 CRK24447.1 - 5e-29 102.0 1.6 1e-28 101.0 1.6 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Zn_clus PF00172.18 CRK24447.1 - 1.4e-08 34.7 11.1 2.9e-08 33.7 11.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_9 PF13454.6 CRK24447.1 - 2.9e-07 30.6 0.2 0.026 14.5 0.2 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Fungal_trans PF04082.18 CRK24447.1 - 6.2e-07 28.7 0.7 1.1e-06 27.9 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain NAD_binding_8 PF13450.6 CRK24447.1 - 0.002 18.3 0.0 0.0056 16.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 CRK24447.1 - 0.009 14.9 0.0 0.11 11.3 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_2 PF07992.14 CRK24447.1 - 0.016 14.5 0.0 1.2 8.3 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CRK24447.1 - 0.098 11.7 0.1 0.34 10.0 0.0 1.9 3 0 0 3 3 3 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 CRK24447.1 - 0.13 11.5 0.1 4.3 6.5 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ring_hydroxyl_A PF00848.19 CRK24448.1 - 9.1e-22 78.1 4.7 7e-11 42.5 3.1 2.2 1 1 1 2 2 2 2 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 CRK24448.1 - 2.2e-15 56.4 0.0 4.5e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain CorC_HlyC PF03471.17 CRK24448.1 - 0.14 12.2 0.0 0.43 10.6 0.0 1.8 2 0 0 2 2 2 0 Transporter associated domain Kei1 PF08552.11 CRK24449.1 - 0.11 12.3 0.9 0.17 11.7 0.9 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Sugar_tr PF00083.24 CRK24450.1 - 7.6e-66 222.8 8.8 1.5e-65 221.8 8.8 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK24450.1 - 1.4e-08 34.1 21.9 1.4e-08 34.1 21.9 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily ADH_zinc_N_2 PF13602.6 CRK24451.1 - 3.9e-28 99.2 0.0 6.4e-28 98.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 CRK24451.1 - 2.2e-15 56.8 0.0 4.6e-15 55.7 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CRK24451.1 - 3.5e-08 33.3 1.7 2.5e-07 30.5 0.0 2.6 1 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain Glycogen_syn PF05693.13 CRK24477.1 - 1.1e-116 390.9 0.1 1.3e-116 390.7 0.1 1.0 1 0 0 1 1 1 1 Glycogen synthase RNA_pol_I_A49 PF06870.12 CRK24482.1 - 2.1e-97 326.4 0.6 2.5e-97 326.2 0.6 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor RNA_pol_I_A49 PF06870.12 CRK24484.1 - 1.5e-96 323.6 0.8 1.8e-96 323.3 0.8 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor CMAS PF02353.20 CRK24485.1 - 6.1e-59 199.5 0.0 3.8e-45 154.3 0.0 2.1 2 0 0 2 2 2 2 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 CRK24485.1 - 3.7e-08 34.0 0.0 2e-07 31.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CRK24485.1 - 6.3e-08 32.6 0.0 1.2e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CRK24485.1 - 9.1e-07 29.4 0.0 1.9e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 CRK24485.1 - 0.045 13.3 0.0 0.071 12.6 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 PCMT PF01135.19 CRK24485.1 - 0.17 11.6 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) eRF1_2 PF03464.15 CRK24487.1 - 6.1e-45 152.8 0.0 1.5e-44 151.6 0.0 1.7 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 CRK24487.1 - 7.1e-39 132.8 0.7 1.8e-38 131.5 0.7 1.8 1 0 0 1 1 1 1 eRF1 domain 3 TPR_2 PF07719.17 CRK24487.1 - 1.7e-29 99.5 20.5 0.0018 18.3 0.2 11.7 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_1 PF00515.28 CRK24487.1 - 5.6e-29 98.7 14.4 7.7e-05 22.3 0.1 10.7 11 0 0 11 11 10 8 Tetratricopeptide repeat TPR_8 PF13181.6 CRK24487.1 - 9.4e-22 75.4 11.5 0.0081 16.3 0.1 10.9 11 0 0 11 11 11 4 Tetratricopeptide repeat eRF1_1 PF03463.15 CRK24487.1 - 1.8e-20 73.3 0.0 4.1e-20 72.1 0.0 1.7 1 0 0 1 1 1 1 eRF1 domain 1 TPR_7 PF13176.6 CRK24487.1 - 4.8e-20 70.0 8.9 0.0041 17.0 0.0 8.7 9 0 0 9 9 7 5 Tetratricopeptide repeat TPR_12 PF13424.6 CRK24487.1 - 2.9e-16 59.5 23.9 2e-05 24.8 0.1 9.8 9 2 0 10 10 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 CRK24487.1 - 1e-15 57.1 25.9 0.00089 19.9 0.0 12.1 10 3 2 12 12 11 2 Tetratricopeptide repeat TPR_19 PF14559.6 CRK24487.1 - 1.3e-14 54.4 23.3 0.32 11.5 0.3 9.6 7 3 2 9 9 8 5 Tetratricopeptide repeat TPR_10 PF13374.6 CRK24487.1 - 3.3e-11 42.7 9.7 0.0027 17.5 0.1 8.1 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_11 PF13414.6 CRK24487.1 - 5.9e-11 41.9 6.2 0.12 12.0 0.0 7.4 7 0 0 7 7 5 3 TPR repeat TPR_6 PF13174.6 CRK24487.1 - 4.2e-10 39.6 19.6 0.01 16.4 0.0 11.4 13 0 0 13 13 10 1 Tetratricopeptide repeat TPR_17 PF13431.6 CRK24487.1 - 2.5e-09 36.9 4.9 0.13 12.7 0.1 8.9 9 0 0 9 9 8 1 Tetratricopeptide repeat baeRF_family10 PF18854.1 CRK24487.1 - 3e-09 37.3 1.7 8.9e-09 35.7 0.0 2.7 3 0 0 3 3 2 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 CRK24487.1 - 2.5e-08 34.3 0.0 1.1e-07 32.2 0.0 2.1 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor TPR_16 PF13432.6 CRK24487.1 - 8.8e-08 32.7 32.4 0.007 17.0 0.1 9.5 11 1 2 13 13 10 4 Tetratricopeptide repeat PknG_TPR PF16918.5 CRK24487.1 - 0.00026 19.8 0.3 0.031 13.0 0.1 2.8 2 0 0 2 2 2 1 Protein kinase G tetratricopeptide repeat ANAPC3 PF12895.7 CRK24487.1 - 0.015 15.5 11.3 4.8 7.5 0.5 6.5 6 0 0 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.9 CRK24487.1 - 0.017 14.8 13.6 1.6 8.4 0.6 5.1 3 2 2 5 5 5 0 Tetratricopeptide repeat-like domain DUF2225 PF09986.9 CRK24487.1 - 0.087 12.5 3.4 3.5 7.3 0.0 4.0 3 1 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_9 PF13371.6 CRK24487.1 - 0.35 11.0 8.9 0.83 9.8 0.0 5.6 7 1 0 7 7 5 0 Tetratricopeptide repeat TPR_3 PF07720.12 CRK24487.1 - 0.57 10.2 3.6 0.96 9.5 0.1 3.1 3 0 0 3 3 2 0 Tetratricopeptide repeat PPR PF01535.20 CRK24487.1 - 0.83 10.0 9.0 5.5 7.5 0.1 5.5 6 0 0 6 6 4 0 PPR repeat SNAP PF14938.6 CRK24487.1 - 1.9 7.9 10.7 1.5 8.2 1.2 4.3 4 2 0 4 4 4 0 Soluble NSF attachment protein, SNAP Peroxin-3 PF04882.12 CRK24488.1 - 5.7e-47 160.8 0.0 5.9e-47 160.7 0.0 1.0 1 0 0 1 1 1 1 Peroxin-3 DGCR6 PF07324.11 CRK24488.1 - 0.013 15.1 0.0 0.017 14.8 0.0 1.1 1 0 0 1 1 1 0 DiGeorge syndrome critical region 6 (DGCR6) protein Sybindin PF04099.12 CRK24489.1 - 4.7e-21 75.2 0.0 7.4e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 Sybindin-like family CAP_N PF01213.19 CRK24489.1 - 0.097 12.1 2.2 0.13 11.7 2.2 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Dscam_C PF12355.8 CRK24489.1 - 0.26 12.2 2.8 0.44 11.5 2.8 1.3 1 0 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal SUIM_assoc PF16619.5 CRK24489.1 - 0.89 9.7 12.3 1.7 8.7 12.3 1.5 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Pkinase PF00069.25 CRK24490.1 - 1.7e-15 57.1 0.0 7.8e-10 38.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CRK24490.1 - 3.1e-07 29.9 0.1 1.1e-05 24.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 CRK24491.1 - 0.03 13.7 0.0 0.03 13.7 0.0 1.0 1 0 0 1 1 1 0 Protein kinase domain zf-C2H2 PF00096.26 CRK24501.1 - 5.4e-10 39.2 13.1 5.4e-05 23.4 7.1 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CRK24501.1 - 2.5e-06 27.8 12.1 0.003 18.3 6.1 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CRK24501.1 - 1.4e-05 25.3 13.0 5.9e-05 23.3 2.9 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_11 PF16622.5 CRK24501.1 - 0.036 13.8 2.7 0.036 13.8 2.7 2.0 2 0 0 2 2 2 0 zinc-finger C2H2-type C1_4 PF07975.12 CRK24501.1 - 0.2 11.9 6.3 0.25 11.6 6.3 1.2 1 0 0 1 1 1 0 TFIIH C1-like domain zf-LYAR PF08790.11 CRK24501.1 - 0.24 11.3 0.2 0.24 11.3 0.2 2.3 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-H2C2_2 PF13465.6 CRK24519.1 - 0.0015 18.9 14.6 0.064 13.7 0.4 4.1 3 0 0 3 3 2 2 Zinc-finger double domain DUF3805 PF12712.7 CRK24519.1 - 0.046 13.9 0.5 14 5.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3805) She9_MDM33 PF05546.11 CRK24519.1 - 0.058 13.2 0.3 14 5.5 0.0 2.3 2 0 0 2 2 2 0 She9 / Mdm33 family zf-C2H2_3rep PF18868.1 CRK24519.1 - 0.077 13.7 6.4 5.2 7.8 0.6 2.8 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-FCS PF06467.14 CRK24519.1 - 0.088 12.8 4.1 16 5.6 0.2 3.9 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif SASP PF00269.20 CRK24519.1 - 0.17 11.9 0.0 34 4.5 0.0 2.4 2 0 0 2 2 2 0 Small, acid-soluble spore proteins, alpha/beta type Cas_CXXC_CXXC PF09706.10 CRK24519.1 - 0.3 11.4 2.7 23 5.3 0.2 2.7 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_CXXC_CXXC) zf-CHCC PF10276.9 CRK24519.1 - 0.33 11.0 14.1 12 6.0 0.3 4.4 4 0 0 4 4 4 0 Zinc-finger domain LEP503 PF15221.6 CRK24519.1 - 0.42 11.0 1.5 58 4.1 0.1 3.2 3 0 0 3 3 3 0 Lens epithelial cell protein LEP503 zf-C2H2 PF00096.26 CRK24519.1 - 1.5 9.4 41.3 0.083 13.4 0.8 6.8 7 0 0 7 7 7 0 Zinc finger, C2H2 type HypA PF01155.19 CRK24519.1 - 1.7 8.7 11.8 5.7 7.0 2.2 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA LtrA PF06772.11 CRK24520.1 - 2.4e-21 76.4 9.7 2.4e-21 76.4 9.7 2.1 2 0 0 2 2 2 1 Bacterial low temperature requirement A protein (LtrA) DSPc PF00782.20 CRK24521.1 - 6.3e-12 45.5 0.0 1.2e-05 25.1 0.0 3.1 3 0 0 3 3 3 3 Dual specificity phosphatase, catalytic domain Vfa1 PF08432.10 CRK24522.1 - 1e-51 175.8 21.6 1.2e-51 175.6 21.6 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 RR_TM4-6 PF06459.12 CRK24522.1 - 0.0046 16.8 15.4 0.006 16.4 15.4 1.1 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 SpoIIIAH PF12685.7 CRK24522.1 - 0.012 15.4 8.8 0.014 15.2 8.8 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein Rtf2 PF04641.12 CRK24522.1 - 0.043 13.2 15.0 0.053 12.9 15.0 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger DUF3109 PF11307.8 CRK24522.1 - 0.045 13.6 3.5 0.086 12.6 3.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3109) CDC45 PF02724.14 CRK24522.1 - 0.058 11.7 17.1 0.068 11.5 17.1 1.0 1 0 0 1 1 1 0 CDC45-like protein Slu7 PF11708.8 CRK24522.1 - 0.065 13.0 16.0 0.081 12.7 16.0 1.2 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor DUF908 PF06012.12 CRK24522.1 - 0.068 12.6 3.4 0.072 12.5 3.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) DUF2152 PF10222.9 CRK24522.1 - 0.074 11.4 0.1 0.13 10.6 0.0 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2152) Ycf1 PF05758.12 CRK24522.1 - 0.089 10.6 9.6 0.096 10.5 9.6 1.1 1 0 0 1 1 1 0 Ycf1 TRAP_alpha PF03896.16 CRK24522.1 - 0.19 10.9 5.3 0.27 10.4 5.3 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit TFIIF_alpha PF05793.12 CRK24522.1 - 0.21 10.1 22.7 0.27 9.8 22.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RNA_pol_Rpc4 PF05132.14 CRK24522.1 - 0.35 11.3 9.4 0.56 10.6 9.4 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 CPSF100_C PF13299.6 CRK24522.1 - 0.4 10.9 9.4 0.59 10.3 9.4 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SID-1_RNA_chan PF13965.6 CRK24522.1 - 0.5 8.7 2.9 0.56 8.6 2.9 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Ureide_permease PF07168.11 CRK24522.1 - 0.52 9.0 6.6 0.73 8.5 6.6 1.3 1 0 0 1 1 1 0 Ureide permease DDHD PF02862.17 CRK24522.1 - 0.55 10.4 5.1 0.66 10.1 5.1 1.2 1 0 0 1 1 1 0 DDHD domain MCM_bind PF09739.9 CRK24522.1 - 0.56 8.6 9.9 0.65 8.4 9.9 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor NPR3 PF03666.13 CRK24522.1 - 0.64 8.7 12.7 0.72 8.6 12.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF913 PF06025.12 CRK24522.1 - 0.78 8.6 4.9 0.84 8.6 4.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CLN3 PF02487.17 CRK24522.1 - 1 8.4 4.4 1.2 8.1 4.4 1.1 1 0 0 1 1 1 0 CLN3 protein SAPS PF04499.15 CRK24522.1 - 1.2 7.8 10.2 1.4 7.6 10.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein NARP1 PF12569.8 CRK24522.1 - 1.6 7.5 18.2 1.9 7.3 18.2 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Presenilin PF01080.17 CRK24522.1 - 1.7 7.3 11.8 2 7.1 11.8 1.1 1 0 0 1 1 1 0 Presenilin DNA_pol_phi PF04931.13 CRK24522.1 - 1.9 6.5 17.8 2.4 6.2 17.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi Hid1 PF12722.7 CRK24522.1 - 2.1 6.4 9.6 2.3 6.2 9.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SLC12 PF03522.15 CRK24522.1 - 2.1 7.3 12.2 2.4 7.1 12.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 RRN3 PF05327.11 CRK24522.1 - 2.2 6.7 10.9 2.6 6.5 10.9 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Iron_permease PF04120.12 CRK24522.1 - 2.6 7.8 4.5 5.3 6.8 4.5 1.5 1 0 0 1 1 1 0 Low affinity iron permease DUF4407 PF14362.6 CRK24522.1 - 2.9 7.2 7.0 3.1 7.1 7.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PPL5 PF18168.1 CRK24522.1 - 3 7.0 11.4 3.9 6.7 11.4 1.2 1 0 0 1 1 1 0 Prim-pol family 5 Cellulose_synt PF03552.14 CRK24522.1 - 3.2 6.1 10.3 4 5.8 10.3 1.1 1 0 0 1 1 1 0 Cellulose synthase Zip PF02535.22 CRK24522.1 - 3.7 6.7 6.0 4.3 6.5 6.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter V_ATPase_I PF01496.19 CRK24522.1 - 5.2 4.9 9.5 5.9 4.7 9.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2151 PF10221.9 CRK24522.1 - 5.9 5.4 14.3 7.1 5.1 14.3 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator Membralin PF09746.9 CRK24522.1 - 6.3 5.7 6.8 7.4 5.5 6.8 1.1 1 0 0 1 1 1 0 Tumour-associated protein DUF3438 PF11920.8 CRK24522.1 - 9.6 5.4 10.4 13 4.9 10.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3438) Rtt106 PF08512.12 CRK24523.1 - 2.8e-30 104.6 0.0 7.5e-30 103.2 0.0 1.8 2 0 0 2 2 2 1 Histone chaperone Rttp106-like PH_18 PF18469.1 CRK24523.1 - 0.0048 16.9 0.0 0.024 14.6 0.0 2.1 2 1 0 2 2 2 1 Pleckstrin homology domain bPH_2 PF03703.14 CRK24523.1 - 0.044 14.0 0.0 0.086 13.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial PH domain PKD PF00801.20 CRK24524.1 - 0.045 13.6 0.1 0.21 11.5 0.0 2.2 2 0 0 2 2 2 0 PKD domain MFS_1 PF07690.16 CRK24526.1 - 4.7e-41 140.9 31.8 1.6e-40 139.1 31.6 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 CRK24526.1 - 0.27 9.5 8.6 0.07 11.4 2.5 2.3 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Lipase_GDSL_2 PF13472.6 CRK24527.1 - 6.2e-08 33.2 0.3 8.8e-08 32.7 0.3 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 CRK24527.1 - 5.4e-06 26.5 0.0 7.3e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Sugar_tr PF00083.24 CRK24529.1 - 5.3e-68 229.9 26.1 6e-68 229.7 26.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK24529.1 - 3.7e-09 36.0 45.9 1.3e-07 30.9 24.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 CRK24529.1 - 4.7e-08 32.0 12.3 0.00013 20.7 3.8 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 CRK24529.1 - 0.002 17.1 6.6 0.002 17.1 6.6 2.3 2 0 0 2 2 2 1 MFS_1 like family ECH_1 PF00378.20 CRK24531.1 - 2e-74 250.1 0.1 2.2e-74 249.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CRK24531.1 - 1.5e-35 123.3 0.3 2.4e-32 112.7 0.1 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase SH3_9 PF14604.6 CRK24532.1 - 4.1e-06 26.6 0.0 4.1e-06 26.6 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 CRK24532.1 - 1e-05 25.0 0.0 2e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CRK24532.1 - 0.07 12.8 0.1 0.21 11.3 0.0 1.8 2 0 0 2 2 2 0 Variant SH3 domain LCE PF14672.6 CRK24533.1 - 0.15 12.7 1.1 26 5.5 0.1 2.4 2 0 0 2 2 2 0 Late cornified envelope PALP PF00291.25 CRK24534.1 - 8.2e-33 114.1 0.1 9.4e-33 113.9 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ERCC3_RAD25_C PF16203.5 CRK24536.1 - 2.6e-114 380.5 0.2 4.4e-114 379.8 0.2 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 CRK24536.1 - 6.1e-33 113.7 0.0 1.5e-32 112.4 0.0 1.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Helicase_C PF00271.31 CRK24536.1 - 1.8e-12 47.6 0.1 4e-12 46.5 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CRK24536.1 - 4.1e-11 43.2 0.0 8.6e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 CRK24536.1 - 7.2e-06 25.0 0.0 9.7e-06 24.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain SIN1 PF05422.12 CRK24536.1 - 0.0062 17.1 2.1 0.15 12.6 0.7 2.8 2 1 0 2 2 2 1 Stress-activated map kinase interacting protein 1 (SIN1) AAA_34 PF13872.6 CRK24536.1 - 0.05 12.5 0.1 0.085 11.7 0.1 1.3 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 zf-CHY PF05495.12 CRK24537.1 - 3.6e-12 46.6 20.2 3.6e-12 46.6 20.2 1.7 2 0 0 2 2 2 1 CHY zinc finger Zn-ribbon_8 PF09723.10 CRK24537.1 - 0.48 10.6 16.3 2 8.6 8.6 2.7 1 1 1 2 2 2 0 Zinc ribbon domain zinc_ribbon_9 PF14369.6 CRK24537.1 - 0.99 9.7 11.0 0.42 10.9 6.6 2.5 1 1 1 2 2 2 0 zinc-ribbon HypA PF01155.19 CRK24537.1 - 3.7 7.6 13.1 5.8 7.0 10.2 2.1 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Proteasome PF00227.26 CRK24538.1 - 3.3e-53 180.0 0.1 5.8e-53 179.2 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit FAD_binding_4 PF01565.23 CRK24538.1 - 9.9e-38 129.0 0.3 4e-37 127.0 0.2 2.0 2 0 0 2 2 2 1 FAD binding domain FAD-oxidase_C PF02913.19 CRK24538.1 - 1.6e-34 119.7 0.0 4.2e-34 118.3 0.0 1.7 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain RCC1 PF00415.18 CRK24538.1 - 3.7e-34 117.1 13.5 2.7e-05 24.7 0.0 7.9 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CRK24538.1 - 1.4e-25 88.5 31.3 6.6e-06 25.8 0.4 6.6 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat Proteasome_A_N PF10584.9 CRK24538.1 - 2.2e-08 33.6 0.0 5.5e-08 32.3 0.0 1.8 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature CH PF00307.31 CRK24539.1 - 9.9e-11 41.8 0.3 1.1e-09 38.4 0.3 1.9 1 1 0 1 1 1 1 Calponin homology (CH) domain DUF4267 PF14087.6 CRK24571.1 - 0.00014 21.9 0.0 0.00014 21.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) NAD_binding_1 PF00175.21 CRK24572.1 - 1.8e-25 89.7 0.0 2.2e-25 89.4 0.0 1.1 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 CRK24572.1 - 8.6e-05 22.7 0.0 9.9e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Ferric reductase NAD binding domain NST1 PF13945.6 CRK24573.1 - 2.4e-27 96.3 0.1 2.4e-27 96.3 0.1 1.4 2 0 0 2 2 2 1 Salt tolerance down-regulator RNA_pol_3_Rpc31 PF11705.8 CRK24573.1 - 0.21 11.8 11.4 0.22 11.8 11.4 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Cwf_Cwc_15 PF04889.12 CRK24573.1 - 0.27 10.9 6.6 0.29 10.9 6.6 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.12 CRK24573.1 - 0.28 9.3 6.4 0.29 9.3 6.4 1.0 1 0 0 1 1 1 0 Nop14-like family RXT2_N PF08595.11 CRK24573.1 - 0.51 10.4 6.5 0.78 9.8 6.5 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal SDA1 PF05285.12 CRK24573.1 - 0.53 9.7 7.1 0.52 9.7 7.1 1.1 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 CRK24573.1 - 0.71 7.9 14.8 0.8 7.7 14.8 1.0 1 0 0 1 1 1 0 DNA polymerase phi FAM176 PF14851.6 CRK24573.1 - 0.72 9.5 3.2 1.1 8.9 3.2 1.4 1 0 0 1 1 1 0 FAM176 family PPP4R2 PF09184.11 CRK24573.1 - 0.96 9.0 7.6 0.99 8.9 7.6 1.2 1 0 0 1 1 1 0 PPP4R2 TFIIA PF03153.13 CRK24573.1 - 1.1 9.1 8.9 1.1 9.2 8.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDC45 PF02724.14 CRK24573.1 - 1.5 7.1 5.3 1.4 7.1 5.3 1.1 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.13 CRK24573.1 - 1.8 8.6 11.7 1.8 8.6 11.7 1.1 1 0 0 1 1 1 0 YL1 nuclear protein TRAP_alpha PF03896.16 CRK24573.1 - 2 7.6 5.0 2.4 7.3 5.0 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Ras PF00071.22 CRK24574.1 - 1.4e-36 125.6 0.0 1.6e-36 125.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CRK24574.1 - 4.3e-14 52.8 0.0 5.9e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase DUF3632 PF12311.8 CRK24576.1 - 8.1e-31 107.8 0.0 1.1e-30 107.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) DUF1772 PF08592.11 CRK24577.1 - 1.8e-16 60.7 1.4 1.8e-16 60.7 1.4 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF1772) Phage_holin_2_4 PF16082.5 CRK24577.1 - 1.7 8.4 6.4 1.5 8.6 0.5 2.7 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like Glyco_hydro_3_C PF01915.22 CRK24578.1 - 7.4e-61 205.7 0.0 1.4e-60 204.8 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 CRK24578.1 - 2.1e-44 152.2 0.0 3.6e-44 151.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 CRK24578.1 - 1e-17 64.0 0.0 2.5e-17 62.8 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 CRK24578.1 - 6.1e-10 39.1 0.0 1.2e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 PA14 domain Sugar_tr PF00083.24 CRK24579.1 - 9.4e-59 199.4 35.4 1.2e-56 192.5 35.4 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK24579.1 - 3.7e-18 65.6 49.2 9.1e-18 64.3 35.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily F-box-like PF12937.7 CRK24580.1 - 1e-08 34.9 0.5 4e-08 33.0 0.5 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CRK24580.1 - 2.8e-07 30.2 1.6 4.8e-07 29.5 0.1 2.1 2 0 0 2 2 2 1 F-box domain Methyltransf_24 PF13578.6 CRK24581.1 - 1.9e-11 44.9 0.0 3e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 CRK24581.1 - 8.8e-06 25.0 0.0 1.3e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Bac_luciferase PF00296.20 CRK24582.1 - 7.7e-58 196.4 3.9 1.2e-57 195.7 3.9 1.3 1 0 0 1 1 1 1 Luciferase-like monooxygenase FMO-like PF00743.19 CRK24582.1 - 1.4e-14 53.5 0.0 4.1e-14 51.9 0.0 1.7 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 CRK24582.1 - 6.3e-10 39.1 0.0 5.1e-09 36.2 0.0 2.6 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CRK24582.1 - 1.2e-08 34.5 0.0 2e-06 27.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 CRK24582.1 - 5.5e-08 32.1 31.0 9.6e-08 31.3 31.0 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Pyr_redox_3 PF13738.6 CRK24582.1 - 2.5e-05 23.7 0.0 0.00012 21.4 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase UNC-93 PF05978.16 CRK24582.1 - 0.0001 22.1 4.2 0.0001 22.1 4.2 2.0 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 NAD_binding_9 PF13454.6 CRK24582.1 - 0.00055 20.0 0.0 0.28 11.2 0.0 3.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 CRK24582.1 - 0.0042 16.7 0.0 4.3 6.8 0.0 2.8 2 0 0 2 2 2 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 CRK24582.1 - 0.0074 15.5 0.0 0.091 11.9 0.0 2.3 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 CRK24582.1 - 0.013 14.7 0.1 0.043 13.0 0.0 1.9 2 0 0 2 2 2 0 Thi4 family ADH_N PF08240.12 CRK24584.1 - 0.00078 19.3 0.0 0.0017 18.2 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CRK24584.1 - 0.0014 18.7 0.0 0.0022 17.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ECH_1 PF00378.20 CRK24585.1 - 9.2e-17 61.2 0.0 1.2e-16 60.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CRK24585.1 - 7.5e-07 28.9 0.0 9.9e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 CRK24585.1 - 0.0064 16.4 0.0 0.76 9.7 0.0 2.3 2 0 0 2 2 2 2 Peptidase family S49 FAD_binding_3 PF01494.19 CRK24586.1 - 1.6e-15 57.3 4.1 4.7e-14 52.4 4.1 2.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 CRK24586.1 - 5.1e-06 26.6 0.3 3.4e-05 24.0 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain UCH PF00443.29 CRK24587.1 - 4e-36 124.8 0.0 1.9e-32 112.8 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CRK24587.1 - 7.1e-06 25.8 6.8 0.00011 22.0 6.8 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Oxysterol_BP PF01237.18 CRK24588.1 - 1.1e-62 212.0 0.3 1.5e-60 205.0 0.3 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein Mac PF12464.8 CRK24589.1 - 1.3e-12 47.7 0.0 2.4e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Maltose acetyltransferase Ac110_PIF PF07280.11 CRK24589.1 - 0.14 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Per os infectivity factor AC110 Asp PF00026.23 CRK24590.1 - 3.7e-09 36.4 0.0 4.3e-09 36.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease MFS_1 PF07690.16 CRK24645.1 - 1.2e-10 40.9 9.7 1.2e-10 40.8 9.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK24645.1 - 1.2e-05 24.4 2.3 1.3e-05 24.3 2.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Amino_oxidase PF01593.24 CRK24661.1 - 0.078 12.2 0.1 0.084 12.1 0.1 1.0 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase SAM_3 PF18016.1 CRK24675.1 - 0.062 13.1 0.2 0.11 12.4 0.2 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Sporozoite_P67 PF05642.11 CRK24675.1 - 0.96 7.4 4.4 1.2 7.2 4.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen AMP-binding PF00501.28 CRK24685.1 - 5.8e-44 150.3 0.0 6.8e-44 150.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 CRK24685.1 - 3.5e-20 71.7 0.3 8.9e-20 70.4 0.3 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus DUF1967 PF09269.11 CRK24685.1 - 0.085 12.8 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) Ribosomal_L16 PF00252.18 CRK24686.1 - 2.1e-31 108.7 0.6 3e-31 108.2 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e RFC1 PF08519.12 CRK24687.1 - 2.9e-30 105.5 0.7 3.9e-19 69.4 0.1 2.9 2 1 1 3 3 3 2 Replication factor RFC1 C terminal domain BRCT PF00533.26 CRK24687.1 - 5.3e-15 55.6 0.0 1.8e-14 53.9 0.0 2.0 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 CRK24687.1 - 3e-08 34.2 0.0 6.8e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 CRK24687.1 - 6.6e-07 29.4 0.0 1.4e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain DNA_pol3_delta PF06144.13 CRK24687.1 - 0.0023 17.7 0.0 0.0061 16.4 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_18 PF13238.6 CRK24687.1 - 0.0025 18.4 0.9 0.009 16.6 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CRK24687.1 - 0.0054 17.0 0.0 0.016 15.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CRK24687.1 - 0.008 16.6 0.1 0.05 14.0 0.1 2.2 1 1 1 2 2 2 1 AAA ATPase domain NTPase_1 PF03266.15 CRK24687.1 - 0.019 14.9 0.1 0.28 11.1 0.0 2.4 3 0 0 3 3 3 0 NTPase AAA_33 PF13671.6 CRK24687.1 - 0.073 13.2 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 CRK24687.1 - 0.08 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 CRK24687.1 - 0.12 12.4 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 CRK24687.1 - 0.24 11.6 0.0 0.24 11.6 0.0 2.2 3 0 0 3 3 2 0 AAA domain GrpE PF01025.19 CRK24689.1 - 1.7e-48 164.4 0.4 2.3e-48 164.0 0.4 1.1 1 0 0 1 1 1 1 GrpE PEARLI-4 PF05278.12 CRK24689.1 - 0.066 12.8 0.2 0.11 12.1 0.2 1.3 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) GrpE PF01025.19 CRK24690.1 - 3.3e-06 26.9 1.1 4.6e-06 26.4 1.1 1.1 1 0 0 1 1 1 1 GrpE PEARLI-4 PF05278.12 CRK24690.1 - 0.14 11.8 0.2 0.17 11.5 0.2 1.1 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) Hormone_3 PF00159.18 CRK24692.1 - 0.051 13.7 1.0 0.57 10.3 0.0 2.8 3 0 0 3 3 3 0 Pancreatic hormone peptide DUF3382 PF11862.8 CRK24692.1 - 0.88 9.9 4.3 1.7 9.0 4.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3382) RNA_pol_A_bac PF01000.26 CRK24694.1 - 1.1e-31 109.4 0.0 1.9e-31 108.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 CRK24694.1 - 5.1e-14 51.5 0.0 7.5e-14 50.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Mito_carr PF00153.27 CRK24695.1 - 3e-53 177.7 0.4 1.2e-19 70.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CRK24695.1 - 0.0079 15.4 0.1 0.016 14.4 0.1 1.4 1 0 0 1 1 1 1 Gammaproteobacterial serine protease RNA_pol_A_bac PF01000.26 CRK24698.1 - 8.8e-32 109.8 0.0 1.6e-31 109.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 CRK24698.1 - 7e-18 63.8 0.0 9.2e-18 63.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Mito_carr PF00153.27 CRK24699.1 - 7.6e-49 163.6 0.2 3.4e-15 55.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CRK24699.1 - 0.0072 15.5 0.2 0.015 14.5 0.2 1.4 1 0 0 1 1 1 1 Gammaproteobacterial serine protease tRNA-synt_2d PF01409.20 CRK24700.1 - 2.6e-45 154.8 1.6 1.3e-22 80.5 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 CRK24700.1 - 4.8e-25 87.8 0.0 1e-24 86.8 0.0 1.6 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain adh_short PF00106.25 CRK24700.1 - 1e-15 57.7 0.1 1.8e-15 56.9 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK24700.1 - 7e-10 38.9 0.0 1.2e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK24700.1 - 9.7e-06 25.6 0.0 1.6e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 KR domain FDX-ACB PF03147.14 CRK24701.1 - 6.9e-25 87.3 0.0 1.1e-24 86.7 0.0 1.3 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain tRNA-synt_2d PF01409.20 CRK24701.1 - 8.5e-24 84.4 0.0 1.2e-23 83.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) Calcipressin PF04847.12 CRK24701.1 - 2.1e-14 53.7 0.0 2.9e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Calcipressin Calcipressin PF04847.12 CRK24702.1 - 1.3e-52 178.3 0.1 2e-52 177.6 0.1 1.3 1 0 0 1 1 1 1 Calcipressin DUF2236 PF09995.9 CRK24703.1 - 3.8e-48 164.7 21.5 4.9e-37 128.3 7.0 3.2 2 1 1 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2236) TRAP-delta PF05404.12 CRK24703.1 - 0.084 12.4 0.0 17 4.9 0.0 2.3 2 0 0 2 2 2 0 Translocon-associated protein, delta subunit precursor (TRAP-delta) p450 PF00067.22 CRK24704.1 - 1e-27 97.0 0.0 4.4e-25 88.4 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 FA_hydroxylase PF04116.13 CRK24705.1 - 5.9e-20 72.0 19.8 4.7e-19 69.1 19.8 2.2 1 1 0 1 1 1 1 Fatty acid hydroxylase superfamily ERG4_ERG24 PF01222.17 CRK24706.1 - 2.1e-70 237.7 9.1 2.4e-70 237.4 9.1 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 CRK24706.1 - 0.019 14.5 2.5 0.038 13.5 2.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1295) MFS_1 PF07690.16 CRK24707.1 - 2.8e-10 39.7 43.6 6.8e-05 21.9 18.3 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_prot_Gp6 PF05133.14 CRK24708.1 - 0.18 10.8 0.1 0.26 10.3 0.1 1.1 1 0 0 1 1 1 0 Phage portal protein, SPP1 Gp6-like HiaBD2 PF15403.6 CRK24709.1 - 0.12 12.8 0.7 0.21 12.0 0.7 1.3 1 0 0 1 1 1 0 HiaBD2_N domain of Trimeric autotransporter adhesin (GIN) MFS_1 PF07690.16 CRK24711.1 - 3.2e-15 55.9 48.8 8.4e-12 44.7 32.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_prot_Gp6 PF05133.14 CRK24712.1 - 0.18 10.8 0.1 0.26 10.3 0.1 1.1 1 0 0 1 1 1 0 Phage portal protein, SPP1 Gp6-like KxDL PF10241.9 CRK24714.1 - 1.9e-30 105.0 2.1 2.8e-30 104.4 2.1 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein DUF2385 PF09539.10 CRK24714.1 - 0.0041 17.6 0.6 0.0074 16.8 0.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2385) XylR_N PF06505.11 CRK24714.1 - 0.063 13.0 0.1 0.095 12.5 0.1 1.2 1 0 0 1 1 1 0 Activator of aromatic catabolism P22_Cro PF14549.6 CRK24714.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 DNA-binding transcriptional regulator Cro CTP_transf_1 PF01148.20 CRK24715.1 - 0.013 15.3 1.0 0.014 15.1 1.0 1.1 1 0 0 1 1 1 0 Cytidylyltransferase family MTBP_C PF14920.6 CRK24716.1 - 5.2 6.8 7.9 7.2 6.3 7.9 1.1 1 0 0 1 1 1 0 MDM2-binding DEAD PF00270.29 CRK24718.1 - 4.9e-40 137.2 0.0 1e-39 136.2 0.0 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CRK24718.1 - 4.7e-23 81.7 0.0 9.5e-23 80.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CRK24718.1 - 1.1e-19 70.4 0.1 2.2e-19 69.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 CRK24718.1 - 7.4e-05 22.8 0.1 0.00033 20.7 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Band_7 PF01145.25 CRK24720.1 - 6.4e-28 98.0 3.3 1.1e-27 97.2 3.3 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 CRK24720.1 - 0.08 12.6 0.2 0.13 12.0 0.2 1.2 1 0 0 1 1 1 0 SPFH domain-Band 7 family DEAD PF00270.29 CRK24722.1 - 1.3e-40 139.1 0.0 2.7e-40 138.0 0.0 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CRK24722.1 - 4.7e-05 23.5 0.0 7.8e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Band_7 PF01145.25 CRK24724.1 - 8.4e-29 100.8 2.9 1.3e-28 100.2 2.9 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 CRK24724.1 - 0.019 14.7 0.2 0.028 14.1 0.2 1.2 1 0 0 1 1 1 0 SPFH domain-Band 7 family Fungal_trans PF04082.18 CRK24728.1 - 1.4e-26 93.1 1.5 2.1e-26 92.5 0.6 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Gal4_dimer PF03902.13 CRK24728.1 - 8.6e-11 41.8 0.1 2.2e-10 40.5 0.1 1.7 1 0 0 1 1 1 1 Gal4-like dimerisation domain Zn_clus PF00172.18 CRK24728.1 - 3.2e-08 33.6 9.7 5e-08 32.9 9.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PRK PF00485.18 CRK24730.1 - 1.6e-09 37.8 0.0 2.2e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family MeaB PF03308.16 CRK24730.1 - 2.9e-05 23.2 0.0 4.3e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 CRK24730.1 - 3.7e-05 24.2 0.0 5.4e-05 23.6 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 CRK24730.1 - 0.00011 22.8 0.0 0.00018 22.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 CRK24730.1 - 0.00025 20.4 0.0 0.00048 19.5 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin APS_kinase PF01583.20 CRK24730.1 - 0.00093 19.1 0.0 0.0016 18.3 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 CRK24730.1 - 0.00094 19.4 0.1 0.0056 16.8 0.0 2.2 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.22 CRK24730.1 - 0.0034 16.6 0.0 0.0053 16.0 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain KTI12 PF08433.10 CRK24730.1 - 0.0067 15.9 0.0 0.0098 15.4 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.6 CRK24730.1 - 0.0076 16.7 0.1 0.027 14.9 0.0 2.0 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.6 CRK24730.1 - 0.01 16.1 0.1 0.031 14.5 0.0 1.8 2 1 0 2 2 2 0 AAA domain Torsin PF06309.11 CRK24730.1 - 0.017 15.3 0.0 0.026 14.6 0.0 1.3 1 0 0 1 1 1 0 Torsin Ploopntkinase3 PF18751.1 CRK24730.1 - 0.028 14.3 0.1 0.073 13.0 0.0 1.7 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA PF00004.29 CRK24730.1 - 0.03 14.7 0.0 0.05 14.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 CRK24730.1 - 0.036 13.3 0.0 0.051 12.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.18 CRK24730.1 - 0.041 13.6 0.0 0.058 13.1 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Thymidylate_kin PF02223.17 CRK24730.1 - 0.052 13.2 0.0 0.11 12.2 0.0 1.6 2 0 0 2 2 2 0 Thymidylate kinase NTPase_1 PF03266.15 CRK24730.1 - 0.072 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 NTPase CbiA PF01656.23 CRK24730.1 - 0.076 13.1 0.0 0.087 12.9 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain NACHT PF05729.12 CRK24730.1 - 0.099 12.6 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_25 PF13481.6 CRK24730.1 - 0.11 12.1 0.0 0.27 10.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 CRK24730.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 CRK24730.1 - 0.16 12.2 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 CRK24730.1 - 0.2 10.6 0.0 0.3 9.9 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Cir_N PF10197.9 CRK24733.1 - 8.3e-09 35.5 2.2 8.3e-09 35.5 2.2 5.0 4 1 0 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR CDC48_2 PF02933.17 CRK24735.1 - 3.5e-05 23.5 1.0 0.00042 20.0 0.1 3.0 3 1 0 3 3 3 1 Cell division protein 48 (CDC48), domain 2 AAA PF00004.29 CRK24735.1 - 0.0034 17.8 0.0 0.006 17.0 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 CRK24735.1 - 0.051 13.0 0.1 0.086 12.2 0.1 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 CRK24735.1 - 0.056 13.2 0.0 0.094 12.4 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.6 CRK24735.1 - 0.062 13.7 0.0 0.1 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain ATPase PF06745.13 CRK24735.1 - 0.076 12.3 0.0 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 KaiC AAA_7 PF12775.7 CRK24735.1 - 0.15 11.6 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region CDC48_N PF02359.18 CRK24735.1 - 0.17 12.1 0.0 0.35 11.1 0.0 1.5 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain AAA_22 PF13401.6 CRK24735.1 - 0.22 11.8 0.0 0.4 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 CRK24736.1 - 2e-08 34.7 0.0 5e-08 33.5 0.0 1.7 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CRK24736.1 - 8.7e-08 31.8 0.1 4.7e-07 29.5 0.2 2.2 2 1 0 2 2 2 1 AAA+ lid domain TIP49 PF06068.13 CRK24736.1 - 0.012 14.8 0.0 0.023 13.9 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain Vps4_C PF09336.10 CRK24736.1 - 0.013 15.4 0.0 0.029 14.4 0.0 1.5 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain AAA_16 PF13191.6 CRK24736.1 - 0.018 15.4 0.0 0.048 14.0 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain ATPase_2 PF01637.18 CRK24736.1 - 0.032 14.2 0.0 3.9 7.3 0.0 2.4 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea Parvo_NS1 PF01057.17 CRK24736.1 - 0.038 13.1 0.0 0.064 12.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 RasGEF PF00617.19 CRK24738.1 - 3.3e-58 196.8 3.2 6.4e-49 166.6 0.7 2.3 2 0 0 2 2 2 2 RasGEF domain RasGEF_N PF00618.20 CRK24738.1 - 5.7e-12 45.8 0.0 1.6e-11 44.4 0.0 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif 2Fe-2S_Ferredox PF11591.8 CRK24738.1 - 0.039 13.8 0.1 31 4.5 0.0 3.7 2 0 0 2 2 2 0 Ferredoxin chloroplastic transit peptide Macscav_rec PF03523.13 CRK24738.1 - 0.15 12.0 0.2 33 4.5 0.0 2.7 2 0 0 2 2 2 0 Macrophage scavenger receptor YLP PF02757.17 CRK24738.1 - 0.5 10.5 3.6 49 4.4 0.3 4.0 2 0 0 2 2 2 0 YLP motif Ribosomal_S2 PF00318.20 CRK24740.1 - 1.8e-30 105.8 0.6 1.1e-14 54.2 0.0 3.1 2 1 1 3 3 3 3 Ribosomal protein S2 40S_SA_C PF16122.5 CRK24740.1 - 6.2e-05 24.3 12.1 0.00012 23.3 12.1 1.5 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus Ribosomal_S15 PF00312.22 CRK24742.1 - 8.6e-24 83.6 0.6 3.1e-23 81.8 0.4 2.0 2 0 0 2 2 2 1 Ribosomal protein S15 vATP-synt_AC39 PF01992.16 CRK24744.1 - 9e-59 199.6 0.0 1.1e-58 199.4 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Ribosomal_S2 PF00318.20 CRK24746.1 - 1.2e-30 106.4 1.4 1e-14 54.3 0.0 3.1 2 1 1 3 3 3 3 Ribosomal protein S2 40S_SA_C PF16122.5 CRK24746.1 - 1.8e-05 26.0 12.1 3.8e-05 25.0 12.1 1.6 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus Ribosomal_S15 PF00312.22 CRK24747.1 - 8.1e-24 83.6 0.6 2.9e-23 81.9 0.4 2.0 2 0 0 2 2 2 1 Ribosomal protein S15 vATP-synt_AC39 PF01992.16 CRK24749.1 - 9.5e-101 337.6 0.0 1.2e-100 337.3 0.0 1.1 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Nop PF01798.18 CRK24751.1 - 1.3e-78 263.6 0.0 2.8e-78 262.6 0.0 1.6 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin ANAPC10 PF03256.16 CRK24751.1 - 1.2e-49 168.4 0.0 2.6e-49 167.4 0.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) NOP5NT PF08156.13 CRK24751.1 - 5.5e-18 65.1 0.2 1.9e-17 63.4 0.2 2.0 1 0 0 1 1 1 1 NOP5NT (NUC127) domain Putative_G5P PF17426.2 CRK24751.1 - 0.069 13.3 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 Putative Gamma DNA binding protein G5P YjbH PF06082.11 CRK24751.1 - 3.6 6.3 6.0 5.8 5.6 6.0 1.2 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH DUF3807 PF12720.7 CRK24751.1 - 8.9 6.5 24.9 6.5 7.0 4.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) TFIID_30kDa PF03540.13 CRK24756.1 - 6.7e-26 90.0 0.3 1.1e-25 89.3 0.3 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Ribosomal_S19 PF00203.21 CRK24758.1 - 1e-27 95.8 0.0 1.3e-27 95.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 XPA_C PF05181.12 CRK24760.1 - 1.2e-24 86.0 0.7 2.4e-24 85.0 0.7 1.5 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.18 CRK24760.1 - 0.00064 19.7 1.5 0.00064 19.7 1.5 1.9 3 0 0 3 3 3 1 XPA protein N-terminal Striatin PF08232.12 CRK24762.1 - 1.1e-40 139.8 4.2 1.1e-40 139.8 4.2 1.9 2 0 0 2 2 2 1 Striatin family WD40 PF00400.32 CRK24762.1 - 6.7e-25 86.9 21.6 3.9e-05 24.3 0.5 7.9 8 1 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK24762.1 - 1.5e-05 25.2 0.0 1.3 9.4 0.0 4.5 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain ADH_N_2 PF16884.5 CRK24762.1 - 0.052 13.4 1.0 0.18 11.7 0.0 2.3 3 0 0 3 3 3 0 N-terminal domain of oxidoreductase eIF2A PF08662.11 CRK24762.1 - 0.12 12.3 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CRK24762.1 - 0.12 11.3 0.0 0.76 8.7 0.0 2.4 3 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 CRK24762.1 - 0.17 10.4 0.0 0.32 9.5 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain CALCOCO1 PF07888.11 CRK24762.1 - 3.3 6.5 10.3 0.61 8.9 6.9 1.5 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF4407 PF14362.6 CRK24762.1 - 5.7 6.2 5.0 9.7 5.4 5.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LicD PF04991.13 CRK24763.1 - 4.2e-24 85.9 3.6 2.1e-17 64.0 1.1 2.1 1 1 1 2 2 2 2 LicD family BC10 PF06726.12 CRK24765.1 - 5.4e-18 65.0 11.2 7.8e-18 64.5 11.2 1.2 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 DUF1837 PF08878.11 CRK24766.1 - 0.028 14.2 0.6 0.081 12.7 0.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1837) WLM PF08325.10 CRK24767.1 - 1.1e-47 162.6 0.0 2e-47 161.7 0.0 1.4 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.17 CRK24767.1 - 4.3e-05 23.6 0.5 7.6e-05 22.8 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF45 SprT-like PF10263.9 CRK24767.1 - 0.014 15.2 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 SprT-like family Reprolysin_5 PF13688.6 CRK24767.1 - 0.12 12.5 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 ER_lumen_recept PF00810.18 CRK24768.1 - 8.8e-54 182.3 8.8 1.5e-53 181.6 8.8 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 CRK24768.1 - 1.5 8.6 13.3 2.5 7.9 0.3 3.8 3 1 1 4 4 4 0 PQ loop repeat Ank_2 PF12796.7 CRK24769.1 - 4.2e-11 43.3 0.1 2.3e-09 37.7 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CRK24769.1 - 2e-10 40.7 3.4 1.7e-07 31.4 0.1 3.9 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 CRK24769.1 - 1.2e-09 38.5 0.9 0.00025 21.6 0.0 5.5 3 1 2 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 CRK24769.1 - 8.8e-08 32.3 3.8 0.0016 18.8 0.0 5.5 6 0 0 6 6 6 1 Ankyrin repeat Ank_3 PF13606.6 CRK24769.1 - 1.8e-07 30.9 0.2 0.0037 17.6 0.0 4.8 4 0 0 4 4 4 1 Ankyrin repeat Peptidase_M28 PF04389.17 CRK24771.1 - 2.8e-33 115.3 0.0 3e-32 111.9 0.0 2.0 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.28 CRK24771.1 - 5.3e-06 26.3 0.4 6.8e-05 22.6 0.4 2.1 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 AA_permease PF00324.21 CRK24772.1 - 8.7e-87 291.7 27.1 1e-86 291.5 27.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CRK24772.1 - 9.5e-28 97.2 29.5 1.2e-27 96.8 29.5 1.0 1 0 0 1 1 1 1 Amino acid permease PA_decarbox PF05870.11 CRK24773.1 - 4.2e-09 36.2 0.3 5e-09 36.0 0.3 1.1 1 0 0 1 1 1 1 Phenolic acid decarboxylase (PAD) Ldh_1_N PF00056.23 CRK24775.1 - 8.3e-40 136.1 0.3 1.3e-39 135.5 0.3 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 CRK24775.1 - 1.2e-20 74.1 0.0 1.9e-20 73.5 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain DAO PF01266.24 CRK24775.1 - 0.00026 20.7 3.4 0.00033 20.3 3.4 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Sacchrp_dh_NADP PF03435.18 CRK24775.1 - 0.0003 21.1 0.6 0.00077 19.7 0.2 1.9 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain ThiF PF00899.21 CRK24775.1 - 0.00073 19.0 0.1 0.0011 18.4 0.1 1.3 1 0 0 1 1 1 1 ThiF family UDPG_MGDP_dh_N PF03721.14 CRK24775.1 - 0.0014 18.3 0.7 0.0025 17.4 0.7 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Glyco_hydro_4 PF02056.16 CRK24775.1 - 0.0017 18.0 2.3 0.13 11.8 0.0 2.8 2 1 1 3 3 3 2 Family 4 glycosyl hydrolase NAD_binding_7 PF13241.6 CRK24775.1 - 0.0017 18.8 0.1 0.003 18.0 0.1 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding 3HCDH_N PF02737.18 CRK24775.1 - 0.0056 16.6 0.1 0.0088 15.9 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 CRK24775.1 - 0.036 14.3 1.2 0.11 12.8 0.4 2.2 2 1 1 3 3 3 0 TrkA-N domain NAD_binding_8 PF13450.6 CRK24775.1 - 0.15 12.3 2.2 0.41 10.9 0.6 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DUF5082 PF16888.5 CRK24776.1 - 0.003 17.8 11.4 0.41 10.9 0.2 5.0 4 0 0 4 4 4 2 Domain of unknown function (DUF5082) DUF2383 PF09537.10 CRK24776.1 - 0.0042 17.4 3.5 0.3 11.4 0.2 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF2383) Collagen PF01391.18 CRK24776.1 - 0.082 12.7 7.6 0.17 11.6 7.6 1.4 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) DUF2207 PF09972.9 CRK24776.1 - 0.21 10.3 2.7 0.55 8.9 0.4 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Phage_holin_3_6 PF07332.11 CRK24776.1 - 0.9 9.6 9.6 3.5 7.7 5.3 2.6 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III H_lectin PF09458.10 CRK24777.1 - 1.1e-31 108.8 0.0 2.3e-11 43.7 0.0 3.5 3 0 0 3 3 3 3 H-type lectin domain DUF4377 PF14302.6 CRK24777.1 - 0.026 14.6 0.0 0.17 12.0 0.0 2.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4377) Astacin PF01400.24 CRK24777.1 - 0.028 14.0 1.7 0.25 10.9 1.7 2.2 1 1 0 1 1 1 0 Astacin (Peptidase family M12A) Reprolysin_5 PF13688.6 CRK24777.1 - 0.071 13.3 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_M10 PF00413.24 CRK24777.1 - 0.14 12.0 2.0 3.4 7.5 2.0 2.6 1 1 0 1 1 1 0 Matrixin LDB19 PF13002.7 CRK24778.1 - 5.5e-12 45.8 0.0 8.8e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.29 CRK24778.1 - 3e-05 24.1 0.0 5.6e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Abdominal-A PF12407.8 CRK24778.1 - 0.045 13.3 2.6 0.084 12.5 2.6 1.4 1 0 0 1 1 1 0 Homeobox protein Glyco_hydro_16 PF00722.21 CRK24780.1 - 3e-13 49.6 0.1 4.2e-13 49.1 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 CRK24780.1 - 3.3e-06 25.8 0.3 0.033 12.6 0.2 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_43 PF04616.14 CRK24781.1 - 1.4e-32 113.2 0.1 1.8e-32 112.8 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_26 PF02156.15 CRK24783.1 - 6.5e-88 295.1 3.0 8.3e-88 294.8 3.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 CBM_35 PF16990.5 CRK24783.1 - 4.1e-27 94.8 1.0 7.4e-27 94.0 1.0 1.4 1 0 0 1 1 1 1 Carbohydrate binding module (family 35) Endotoxin_C PF03944.14 CRK24783.1 - 0.0089 16.4 0.1 0.017 15.5 0.1 1.4 1 0 0 1 1 1 1 delta endotoxin Glyco_hydro_20 PF00728.22 CRK24784.1 - 2.8e-23 82.9 0.1 6.7e-23 81.6 0.1 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.15 CRK24784.1 - 1.1e-10 42.4 0.0 2.4e-10 41.3 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Podoplanin PF05808.11 CRK24785.1 - 0.0006 19.9 0.0 0.00097 19.3 0.0 1.4 1 0 0 1 1 1 1 Podoplanin Gram_pos_anchor PF00746.21 CRK24785.1 - 0.49 10.4 1.7 0.87 9.6 1.7 1.4 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Nop PF01798.18 CRK24787.1 - 3.1e-55 187.1 0.2 3.1e-55 187.1 0.2 1.8 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin Putative_G5P PF17426.2 CRK24787.1 - 0.014 15.5 0.0 0.051 13.7 0.0 2.0 1 0 0 1 1 1 0 Putative Gamma DNA binding protein G5P DUF3807 PF12720.7 CRK24787.1 - 2.2 8.5 25.3 5.4 7.2 5.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) YjbH PF06082.11 CRK24787.1 - 2.3 6.9 7.9 3.2 6.4 7.9 1.2 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH ANAPC10 PF03256.16 CRK24788.1 - 2.6e-50 170.7 0.0 3.7e-50 170.1 0.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) TFIID_30kDa PF03540.13 CRK24789.1 - 6.7e-26 90.0 0.3 1.1e-25 89.3 0.3 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Ribosomal_S19 PF00203.21 CRK24790.1 - 1.7e-28 98.3 0.0 2e-28 98.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 XPA_C PF05181.12 CRK24791.1 - 1.3e-24 85.9 0.7 2.4e-24 85.0 0.7 1.5 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.18 CRK24791.1 - 0.00064 19.7 1.5 0.00064 19.7 1.5 1.9 3 0 0 3 3 3 1 XPA protein N-terminal Striatin PF08232.12 CRK24792.1 - 6.1e-41 140.6 4.2 1.1e-40 139.7 4.2 1.5 1 0 0 1 1 1 1 Striatin family WD40 PF00400.32 CRK24792.1 - 1.1e-24 86.2 21.7 4.1e-05 24.2 0.5 7.8 8 1 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK24792.1 - 2.4e-05 24.6 0.0 1.4 9.3 0.0 4.4 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain ADH_N_2 PF16884.5 CRK24792.1 - 0.05 13.5 0.2 0.19 11.6 0.0 1.9 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase Ge1_WD40 PF16529.5 CRK24792.1 - 0.14 11.1 0.0 0.8 8.6 0.0 2.3 3 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 CRK24792.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A CALCOCO1 PF07888.11 CRK24792.1 - 0.45 9.3 6.9 0.65 8.8 6.9 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like LicD PF04991.13 CRK24793.1 - 4.3e-24 85.9 3.6 2.1e-17 64.0 1.1 2.1 1 1 1 2 2 2 2 LicD family BC10 PF06726.12 CRK24795.1 - 5.4e-18 65.0 11.2 7.8e-18 64.5 11.2 1.2 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 DUF1837 PF08878.11 CRK24796.1 - 0.027 14.3 0.6 0.079 12.7 0.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1837) WLM PF08325.10 CRK24797.1 - 4e-47 160.8 0.0 7.2e-47 159.9 0.0 1.4 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.17 CRK24797.1 - 0.00017 21.7 1.7 0.0003 20.9 1.7 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF45 SprT-like PF10263.9 CRK24797.1 - 0.042 13.7 0.2 0.075 12.9 0.2 1.4 1 0 0 1 1 1 0 SprT-like family Reprolysin_5 PF13688.6 CRK24797.1 - 0.15 12.2 0.1 0.2 11.8 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 ER_lumen_recept PF00810.18 CRK24798.1 - 8.5e-54 182.4 8.9 1.5e-53 181.6 8.9 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor Ank_2 PF12796.7 CRK24799.1 - 1.3e-10 41.7 0.1 1e-08 35.6 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CRK24799.1 - 6.8e-10 39.3 0.3 0.00053 20.5 0.0 4.9 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 CRK24799.1 - 1.1e-09 38.3 3.3 1.6e-07 31.4 0.1 3.8 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.30 CRK24799.1 - 7.8e-07 29.3 4.0 0.0015 18.9 0.0 5.3 6 0 0 6 6 6 1 Ankyrin repeat Ank_3 PF13606.6 CRK24799.1 - 8.6e-07 28.8 0.1 0.0036 17.7 0.0 4.6 4 0 0 4 4 4 1 Ankyrin repeat Zn_clus PF00172.18 CRK24800.1 - 2e-06 27.8 9.2 3.2e-06 27.1 9.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AA_permease PF00324.21 CRK24801.1 - 2.1e-89 300.3 33.3 2.6e-89 300.0 33.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CRK24801.1 - 3.5e-30 105.2 33.4 4.2e-30 104.9 33.4 1.0 1 0 0 1 1 1 1 Amino acid permease Fungal_trans PF04082.18 CRK24802.1 - 5.5e-14 51.8 0.0 9e-14 51.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Flavi_NS4A PF01350.17 CRK24802.1 - 0.095 12.6 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Flavivirus non-structural protein NS4A AA_permease PF00324.21 CRK24803.1 - 4.5e-94 315.7 39.9 5.6e-94 315.4 39.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CRK24803.1 - 5.4e-30 104.6 41.2 6.6e-30 104.3 41.2 1.1 1 0 0 1 1 1 1 Amino acid permease ADH_zinc_N PF00107.26 CRK24804.1 - 1.1e-07 31.9 0.0 2.4e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CRK24804.1 - 1.6e-06 29.2 0.0 4e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CRK24804.1 - 5.4e-05 23.0 0.0 0.00011 22.1 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 CRK24804.1 - 0.1 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Response_reg PF00072.24 CRK24805.1 - 1.1e-20 73.9 0.0 2.2e-20 72.9 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 CRK24805.1 - 3.2e-20 72.7 0.0 6e-20 71.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 CRK24805.1 - 1.6e-09 37.7 0.1 3.9e-09 36.4 0.1 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain AMP-binding PF00501.28 CRK24807.1 - 5.4e-72 242.7 0.0 8.5e-72 242.1 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 CRK24807.1 - 4.2e-28 98.2 0.0 1.8e-15 56.8 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein PP-binding PF00550.25 CRK24807.1 - 2.9e-08 33.9 0.0 6.7e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site NAD_binding_10 PF13460.6 CRK24807.1 - 0.00019 21.4 0.0 0.05 13.5 0.1 2.6 2 0 0 2 2 2 2 NAD(P)H-binding Epimerase PF01370.21 CRK24807.1 - 0.00036 20.1 0.0 0.0011 18.5 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CRK24807.1 - 0.0016 17.9 0.1 0.0025 17.3 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase AMP-binding_C PF13193.6 CRK24807.1 - 0.003 18.5 0.0 0.011 16.7 0.0 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.19 CRK24807.1 - 0.039 13.0 0.0 0.26 10.2 0.0 2.0 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family PSII_Pbs27 PF13326.6 CRK24807.1 - 0.12 12.7 0.1 7.6 6.8 0.0 2.5 2 0 0 2 2 2 0 Photosystem II Pbs27 Lipase_GDSL_2 PF13472.6 CRK24808.1 - 2.1e-07 31.5 0.1 2.8e-07 31.1 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 CRK24808.1 - 0.026 14.5 0.0 0.035 14.1 0.0 1.2 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 CRK24808.1 - 0.13 12.4 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family FMN_dh PF01070.18 CRK24809.1 - 1.1e-65 221.9 0.5 1e-51 176.1 0.1 2.0 1 1 1 2 2 2 2 FMN-dependent dehydrogenase His_biosynth PF00977.21 CRK24809.1 - 0.0001 21.9 0.2 0.07 12.6 0.0 2.6 1 1 1 2 2 2 2 Histidine biosynthesis protein IMPDH PF00478.25 CRK24809.1 - 0.00028 20.0 0.1 0.00052 19.1 0.1 1.6 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 CRK24809.1 - 0.0024 17.1 0.0 0.0035 16.5 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 CRK24809.1 - 0.0041 16.5 0.1 0.0082 15.6 0.1 1.4 2 0 0 2 2 2 1 Nitronate monooxygenase DHO_dh PF01180.21 CRK24809.1 - 0.017 14.4 0.2 0.12 11.6 0.0 1.9 1 1 0 2 2 2 0 Dihydroorotate dehydrogenase Peptidase_M19 PF01244.21 CRK24809.1 - 0.029 13.5 0.0 0.06 12.5 0.0 1.5 1 0 0 1 1 1 0 Membrane dipeptidase (Peptidase family M19) IGPS PF00218.21 CRK24809.1 - 0.2 10.8 0.0 1.9 7.6 0.0 2.0 1 1 1 2 2 2 0 Indole-3-glycerol phosphate synthase Aa_trans PF01490.18 CRK24810.1 - 3.3e-37 128.2 35.1 3.8e-37 128.0 35.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Herpes_teg_N PF04843.12 CRK24810.1 - 0.21 11.3 0.0 0.38 10.4 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus tegument protein, N-terminal conserved region Fungal_trans_2 PF11951.8 CRK24811.1 - 3.2e-19 69.0 2.3 5.3e-19 68.3 2.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK24811.1 - 1.2e-06 28.5 8.3 2e-06 27.8 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_transf_52 PF07922.11 CRK24811.1 - 0.012 14.9 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 52 FtsA PF14450.6 CRK24811.1 - 0.092 13.2 0.0 5.5 7.5 0.0 2.3 2 0 0 2 2 2 0 Cell division protein FtsA CBM-like PF14683.6 CRK24812.1 - 2.6e-24 85.9 0.1 4.4e-24 85.2 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 CRK24812.1 - 2e-19 69.1 3.8 3e-19 68.6 0.1 2.8 3 0 0 3 3 3 1 Polysaccharide lyase family 4, domain II MLTR_LBD PF17765.1 CRK24812.1 - 0.11 12.6 0.1 0.33 11.1 0.0 1.7 2 0 0 2 2 2 0 MmyB-like transcription regulator ligand binding domain DOCK_N PF16172.5 CRK24814.1 - 2.3e-124 415.2 0.0 3.5e-124 414.5 0.0 1.3 1 0 0 1 1 1 1 DOCK N-terminus DOCK-C2 PF14429.6 CRK24814.1 - 1.2e-37 129.7 0.0 2.8e-37 128.4 0.0 1.7 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins DHR-2 PF06920.13 CRK24814.1 - 3.7e-29 101.8 0.4 2.9e-28 98.8 0.3 2.1 1 1 0 1 1 1 1 Dock homology region 2 SH3_1 PF00018.28 CRK24814.1 - 8.5e-05 22.1 0.0 0.00018 21.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CRK24814.1 - 0.00022 21.0 0.0 0.00096 19.0 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 CRK24814.1 - 0.078 12.7 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain Ribonuc_L-PSP PF01042.21 CRK24815.1 - 6.4e-12 45.6 0.1 1e-09 38.5 0.1 2.1 1 1 0 1 1 1 1 Endoribonuclease L-PSP GFA PF04828.14 CRK24816.1 - 5.6e-10 39.4 2.6 8.4e-06 26.0 0.3 3.7 3 1 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme TFIID-18kDa PF02269.16 CRK24817.1 - 9.6e-24 83.2 1.5 1.5e-23 82.6 0.1 2.0 3 0 0 3 3 3 1 Transcription initiation factor IID, 18kD subunit AAA PF00004.29 CRK24818.1 - 2.9e-11 43.9 0.0 4.8e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF5548 PF17702.1 CRK24818.1 - 0.082 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5548) CAP_N PF01213.19 CRK24818.1 - 0.27 10.7 0.5 0.47 9.9 0.5 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Glyco_tranf_2_3 PF13641.6 CRK24820.1 - 1.2e-14 54.8 0.1 1.8e-14 54.2 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 CRK24820.1 - 0.00015 21.6 0.0 0.00025 20.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Peptidase_S8 PF00082.22 CRK24823.1 - 3.4e-34 118.5 4.0 5.3e-34 117.8 4.0 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 CRK24823.1 - 0.0013 19.3 0.0 0.003 18.2 0.0 1.6 1 1 0 1 1 1 1 Peptidase inhibitor I9 Cofilin_ADF PF00241.20 CRK24824.1 - 8.4e-24 83.7 0.1 9.4e-24 83.5 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF3656 PF12392.8 CRK24824.1 - 0.16 12.7 0.0 0.22 12.2 0.0 1.3 1 0 0 1 1 1 0 Collagenase CBM_20 PF00686.19 CRK24826.1 - 2.7e-33 113.7 0.2 6.2e-33 112.6 0.2 1.6 1 0 0 1 1 1 1 Starch binding domain LPMO_10 PF03067.15 CRK24826.1 - 1.2e-11 45.7 3.0 2.5e-11 44.6 3.0 1.6 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 CRK24826.1 - 0.0058 16.6 0.2 0.15 12.0 0.0 2.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 Peptidase_M14 PF00246.24 CRK24827.1 - 1.8e-10 41.2 0.0 2.6e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Cu_amine_oxid PF01179.20 CRK24828.1 - 8.8e-84 281.8 0.3 1.7e-83 280.8 0.0 1.5 2 0 0 2 2 2 1 Copper amine oxidase, enzyme domain GMC_oxred_C PF05199.13 CRK24828.1 - 2.7e-23 83.1 0.1 4.9e-23 82.2 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Cu_amine_oxidN3 PF02728.16 CRK24828.1 - 4.8e-20 71.8 0.1 1e-19 70.8 0.1 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 CRK24828.1 - 3.1e-12 46.6 0.0 6e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain MFS_1 PF07690.16 CRK24829.1 - 2.3e-27 95.9 37.6 8.4e-27 94.0 36.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Multi_Drug_Res PF00893.19 CRK24829.1 - 5 7.8 8.0 0.83 10.4 2.3 2.6 3 0 0 3 3 3 0 Small Multidrug Resistance protein Glyco_hydro_72 PF03198.14 CRK24830.1 - 5.8e-122 406.9 2.1 8.5e-122 406.3 2.1 1.2 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 CRK24830.1 - 2.1e-22 79.6 5.9 6e-22 78.1 5.9 1.9 1 0 0 1 1 1 1 X8 domain CFEM PF05730.11 CRK24831.1 - 5e-11 42.5 10.8 8.7e-11 41.8 10.8 1.4 1 0 0 1 1 1 1 CFEM domain FmdE PF02663.14 CRK24831.1 - 0.053 13.6 0.0 0.071 13.2 0.0 1.3 1 0 0 1 1 1 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon ADH_zinc_N PF00107.26 CRK24832.1 - 2.1e-18 66.5 0.0 3.6e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CRK24832.1 - 1.6e-11 45.4 0.0 6.7e-11 43.4 0.0 2.2 3 0 0 3 3 3 1 Zinc-binding dehydrogenase Glycos_transf_2 PF00535.26 CRK24832.1 - 0.19 11.5 0.0 0.44 10.3 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 Sugar_tr PF00083.24 CRK24833.1 - 5.1e-48 164.1 6.1 5.6e-48 163.9 6.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Imm7 PF15585.6 CRK24833.1 - 0.068 13.5 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 7 Glyco_hydro_3_C PF01915.22 CRK24834.1 - 3.7e-53 180.5 0.0 5.8e-53 179.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 CRK24834.1 - 1e-52 179.5 0.0 1.7e-52 178.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 CRK24834.1 - 2.5e-19 69.1 0.7 6.2e-19 67.9 0.7 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 CRK24834.1 - 1.8e-14 53.8 0.0 3.3e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 PA14 domain Sugar_tr PF00083.24 CRK24836.1 - 2.7e-87 293.5 10.8 2.7e-87 293.5 10.8 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter AAA_12 PF13087.6 CRK24836.1 - 5.6e-40 137.1 0.0 1.4e-39 135.8 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA PF00004.29 CRK24836.1 - 3.2e-31 108.5 0.0 2.3e-12 47.5 0.0 5.0 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 CRK24836.1 - 2.7e-28 99.5 14.5 8.7e-14 51.9 0.3 5.7 4 1 1 5 5 5 3 AAA domain MFS_1 PF07690.16 CRK24836.1 - 1.7e-25 89.7 34.0 1.5e-20 73.4 26.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily AAA_lid_6 PF17866.1 CRK24836.1 - 3.1e-18 65.7 2.4 6.3e-08 32.7 0.3 3.3 2 0 0 2 2 2 2 AAA lid domain AAA_30 PF13604.6 CRK24836.1 - 6.6e-18 65.1 2.3 1.1e-08 35.0 0.0 4.7 4 1 0 4 4 4 3 AAA domain AAA_19 PF13245.6 CRK24836.1 - 4.7e-15 56.2 0.3 1.4e-08 35.2 0.1 4.0 3 0 0 3 3 3 3 AAA domain AAA_22 PF13401.6 CRK24836.1 - 2e-08 34.6 8.0 0.056 13.7 0.8 6.5 4 4 1 5 5 4 2 AAA domain Mg_chelatase PF01078.21 CRK24836.1 - 1.3e-06 27.9 0.2 0.35 10.2 0.0 3.6 4 0 0 4 4 3 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CRK24836.1 - 3.1e-06 27.2 0.1 0.47 10.5 0.0 3.9 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CRK24836.1 - 1.1e-05 25.9 2.2 1.2 9.5 0.0 4.6 4 0 0 4 4 4 1 AAA ATPase domain ResIII PF04851.15 CRK24836.1 - 1.9e-05 24.7 1.4 0.017 15.1 0.0 4.6 5 0 0 5 5 5 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 CRK24836.1 - 4e-05 23.5 0.0 16 5.1 0.0 5.9 6 0 0 6 6 6 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 CRK24836.1 - 5.6e-05 23.5 0.0 6.4 7.2 0.0 4.3 4 0 0 4 4 4 0 RNA helicase PhoH PF02562.16 CRK24836.1 - 9e-05 22.0 0.3 0.021 14.3 0.0 3.2 3 0 0 3 3 3 1 PhoH-like protein IstB_IS21 PF01695.17 CRK24836.1 - 0.00013 21.8 0.0 3.1 7.5 0.0 3.5 3 0 0 3 3 3 1 IstB-like ATP binding protein RuvB_N PF05496.12 CRK24836.1 - 0.00014 21.7 0.0 0.36 10.6 0.0 3.7 4 0 0 4 4 4 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 CRK24836.1 - 0.00016 21.5 0.2 1.1 8.9 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 CRK24836.1 - 0.0014 19.2 0.3 14 6.3 0.2 4.0 3 0 0 3 3 3 0 AAA domain DUF2075 PF09848.9 CRK24836.1 - 0.0014 17.9 2.2 0.16 11.2 0.0 4.0 4 0 0 4 4 4 1 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 CRK24836.1 - 0.0094 15.0 1.9 1.7 7.6 0.0 3.5 4 0 0 4 4 4 1 Type II/IV secretion system protein AAA_7 PF12775.7 CRK24836.1 - 0.011 15.3 0.2 6.1 6.3 0.0 3.4 3 0 0 3 3 3 0 P-loop containing dynein motor region Helicase_RecD PF05127.14 CRK24836.1 - 0.011 15.5 0.6 0.61 9.9 0.0 3.1 3 0 0 3 3 2 0 Helicase AAA_33 PF13671.6 CRK24836.1 - 0.028 14.6 8.8 4.7 7.4 0.0 4.7 5 0 0 5 5 3 0 AAA domain Torsin PF06309.11 CRK24836.1 - 0.041 14.0 0.0 13 5.9 0.0 3.4 3 0 0 3 3 3 0 Torsin Brr6_like_C_C PF10104.9 CRK24836.1 - 0.053 13.3 0.4 0.12 12.2 0.4 1.6 1 0 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain AAA_10 PF12846.7 CRK24836.1 - 0.065 12.1 0.0 0.52 9.2 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain ATPase PF06745.13 CRK24836.1 - 0.082 12.2 0.5 4 6.7 0.0 2.9 3 0 0 3 3 3 0 KaiC Arg_decarbox_C PF17944.1 CRK24836.1 - 0.097 13.2 0.4 0.69 10.5 0.0 2.7 2 0 0 2 2 1 0 Arginine decarboxylase C-terminal helical extension SRP54 PF00448.22 CRK24836.1 - 0.14 11.8 0.4 0.67 9.5 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_17 PF13207.6 CRK24836.1 - 0.35 11.3 3.6 9 6.7 0.2 3.8 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.6 CRK24836.1 - 0.81 9.2 2.8 27 4.2 0.1 4.2 5 1 0 5 5 4 0 AAA domain MMU163 PF17119.5 CRK24836.1 - 1 8.5 3.9 0.6 9.2 1.7 1.7 2 0 0 2 2 1 0 Mitochondrial protein up-regulated during meiosis DUF4149 PF13664.6 CRK24836.1 - 6.5 7.1 10.6 0.2 12.0 1.9 2.9 3 0 0 3 3 2 0 Domain of unknown function (DUF4149) ABC_membrane PF00664.23 CRK24838.1 - 5.9e-24 85.2 0.5 8.1e-18 65.0 0.7 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CRK24838.1 - 8.5e-13 49.0 0.0 1.2e-12 48.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 CRK24838.1 - 0.0041 16.8 0.1 0.009 15.7 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 CRK24838.1 - 0.035 14.6 0.0 0.05 14.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 CRK24838.1 - 0.063 13.2 0.1 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_18 PF13238.6 CRK24838.1 - 0.088 13.4 0.0 0.14 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 CRK24838.1 - 0.091 12.5 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF3987 PF13148.6 CRK24838.1 - 0.11 11.5 0.0 0.2 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) AAA_25 PF13481.6 CRK24838.1 - 0.17 11.4 0.0 0.34 10.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 CRK24838.1 - 0.18 11.9 0.3 0.27 11.3 0.3 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain ABC_membrane PF00664.23 CRK24839.1 - 3.3e-44 151.6 22.0 1.8e-38 132.8 16.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CRK24839.1 - 1.9e-42 145.0 0.0 2.8e-30 105.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CRK24839.1 - 7.2e-14 51.8 0.2 2.2e-05 24.0 0.0 3.2 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CRK24839.1 - 9e-05 22.4 0.4 3.1 7.5 0.0 3.3 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 CRK24839.1 - 0.00013 21.7 0.7 0.015 15.0 0.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CRK24839.1 - 0.00089 19.7 3.6 0.0078 16.6 0.2 2.5 2 0 0 2 2 2 1 AAA ATPase domain SbcCD_C PF13558.6 CRK24839.1 - 0.001 19.3 1.8 2.6 8.4 0.0 3.5 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.12 CRK24839.1 - 0.0016 17.7 0.0 0.0035 16.6 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.6 CRK24839.1 - 0.0025 18.1 0.1 0.17 12.2 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CRK24839.1 - 0.0067 16.2 0.1 0.02 14.6 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain Tex_YqgF PF16921.5 CRK24839.1 - 0.028 14.9 0.1 0.077 13.5 0.1 1.7 1 0 0 1 1 1 0 Tex protein YqgF-like domain AAA PF00004.29 CRK24839.1 - 0.037 14.4 0.2 8 6.9 0.0 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.9 CRK24839.1 - 0.047 12.5 0.3 1.5 7.5 0.0 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 CRK24839.1 - 0.08 12.8 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase Pec_lyase_C PF00544.19 CRK24840.1 - 2.2e-39 135.2 1.7 3.2e-39 134.7 1.7 1.2 1 0 0 1 1 1 1 Pectate lyase CBM_1 PF00734.18 CRK24840.1 - 2.1e-12 46.8 14.9 5.7e-12 45.4 14.9 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain Glyco_hydro_61 PF03443.14 CRK24841.1 - 1.8e-52 178.3 0.0 2.9e-52 177.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF5624 PF18538.1 CRK24841.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) Melibiase_2 PF16499.5 CRK24842.1 - 3.5e-51 174.1 0.6 6.5e-51 173.2 0.6 1.5 1 1 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 CRK24842.1 - 2.2e-12 46.9 0.5 2.2e-12 46.9 0.5 1.9 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 CRK24842.1 - 0.036 13.0 0.4 0.38 9.6 0.0 2.5 3 0 0 3 3 3 0 Melibiase Phospholip_A2_3 PF09056.11 CRK24843.1 - 6.9e-40 136.1 3.5 9.2e-40 135.7 3.5 1.2 1 0 0 1 1 1 1 Prokaryotic phospholipase A2 PLA2G12 PF06951.11 CRK24843.1 - 0.013 15.4 0.3 0.019 14.9 0.3 1.3 1 1 0 1 1 1 0 Group XII secretory phospholipase A2 precursor (PLA2G12) Arm-DNA-bind_2 PF12167.8 CRK24843.1 - 0.15 12.0 1.3 3.7 7.5 0.4 2.3 2 0 0 2 2 2 0 Arm DNA-binding domain Herpes_UL49_5 PF05702.11 CRK24844.1 - 0.12 12.5 0.1 0.28 11.3 0.1 1.6 1 1 0 1 1 1 0 Herpesvirus UL49.5 envelope/tegument protein ECH_1 PF00378.20 CRK24845.1 - 1.2e-70 237.7 0.1 1.4e-70 237.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CRK24845.1 - 2.7e-31 109.3 0.3 1.7e-29 103.4 0.2 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase SDH_sah PF01972.16 CRK24845.1 - 0.12 11.3 0.1 0.24 10.4 0.1 1.4 1 1 0 1 1 1 0 Serine dehydrogenase proteinase AMP-binding PF00501.28 CRK24846.1 - 1.1e-84 284.5 0.0 1.7e-84 283.9 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CRK24846.1 - 0.02 15.9 0.0 0.048 14.6 0.0 1.7 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain FtsX PF02687.21 CRK24846.1 - 0.54 10.8 6.5 0.17 12.4 3.1 1.9 2 0 0 2 2 2 0 FtsX-like permease family Fungal_trans PF04082.18 CRK24847.1 - 1.5e-09 37.3 0.8 4e-09 35.9 0.8 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK24847.1 - 6.6e-09 35.7 4.6 1.4e-08 34.7 4.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PhoU PF01895.19 CRK24847.1 - 0.0084 16.6 0.2 1.9 9.0 0.1 2.6 2 0 0 2 2 2 2 PhoU domain ABC2_membrane PF01061.24 CRK24848.1 - 2e-71 239.7 59.3 3.7e-45 153.9 27.8 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 CRK24848.1 - 1.5e-38 132.4 0.0 3e-19 69.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 CRK24848.1 - 4.1e-25 87.5 16.3 7.3e-25 86.7 0.0 4.0 4 0 0 4 4 4 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 CRK24848.1 - 5.2e-09 35.7 44.8 1.8e-07 30.6 19.4 2.8 2 1 1 3 3 3 2 ABC-2 family transporter protein ABC_trans_N PF14510.6 CRK24848.1 - 4e-07 30.5 0.0 1e-06 29.3 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 CRK24848.1 - 4.2e-06 27.3 0.4 0.0036 17.7 0.1 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 CRK24848.1 - 5.7e-05 22.8 0.3 0.0049 16.5 0.1 2.4 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 CRK24848.1 - 0.0002 21.3 0.4 0.0026 17.7 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 CRK24848.1 - 0.00039 20.1 0.3 0.082 12.7 0.1 2.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.6 CRK24848.1 - 0.00078 19.6 0.4 1.5 9.0 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 CRK24848.1 - 0.0013 18.5 0.5 0.92 9.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 CRK24848.1 - 0.0032 17.7 1.3 1.1 9.5 0.5 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CRK24848.1 - 0.0041 17.4 0.0 1.3 9.3 0.0 3.3 3 0 0 3 3 3 1 AAA domain cobW PF02492.19 CRK24848.1 - 0.0048 16.5 0.8 1.7 8.2 0.4 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 CRK24848.1 - 0.0085 16.6 0.0 2.7 8.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 CRK24848.1 - 0.083 12.8 0.6 4.1 7.3 0.2 2.4 2 0 0 2 2 2 0 NACHT domain AAA_21 PF13304.6 CRK24848.1 - 0.18 11.6 0.0 5.2 6.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Glyco_transf_90 PF05686.12 CRK24849.1 - 3.5e-17 62.4 7.2 2e-13 50.0 0.1 2.6 3 0 0 3 3 3 2 Glycosyl transferase family 90 Fungal_trans PF04082.18 CRK24850.1 - 5.8e-05 22.2 0.0 0.00019 20.6 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Gly-rich_Ago1 PF12764.7 CRK24851.1 - 0.1 13.4 0.2 0.12 13.2 0.2 1.1 1 0 0 1 1 1 0 Glycine-rich region of argonaut PGPGW PF09656.10 CRK24853.1 - 0.075 12.6 0.3 0.075 12.6 0.3 3.1 3 0 0 3 3 3 0 Putative transmembrane protein (PGPGW) Glyoxalase PF00903.25 CRK24854.1 - 1.2e-06 28.7 0.0 5e-06 26.7 0.0 1.8 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 CRK24854.1 - 6.3e-06 26.4 0.0 8.2e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 CRK24854.1 - 0.046 13.8 0.0 0.14 12.2 0.0 1.8 1 1 0 1 1 1 0 Glyoxalase-like domain OPT PF03169.15 CRK24855.1 - 1.6e-103 347.4 33.4 5.5e-60 203.7 17.5 2.0 1 1 1 2 2 2 2 OPT oligopeptide transporter protein WSC PF01822.19 CRK24856.1 - 6.9e-40 135.1 35.6 1.2e-17 63.9 7.2 4.1 4 0 0 4 4 4 3 WSC domain ASH PF15780.5 CRK24856.1 - 5.4e-08 32.9 0.1 0.014 15.6 0.0 3.1 2 0 0 2 2 2 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Proteasome PF00227.26 CRK24858.1 - 4.3e-41 140.5 0.3 5.7e-41 140.1 0.3 1.2 1 0 0 1 1 1 1 Proteasome subunit Evr1_Alr PF04777.13 CRK24858.1 - 3.2e-26 91.7 0.0 1.3e-25 89.7 0.0 2.1 2 0 0 2 2 2 1 Erv1 / Alr family LmjF365940-deam PF14421.6 CRK24858.1 - 0.016 14.8 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 A distinct subfamily of CDD/CDA-like deaminases SNAD4 PF18750.1 CRK24858.1 - 0.061 13.5 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 CDV3 PF15359.6 CRK24858.1 - 0.068 13.7 0.5 0.13 12.7 0.5 1.4 1 0 0 1 1 1 0 Carnitine deficiency-associated protein 3 APOBEC4 PF18775.1 CRK24858.1 - 0.089 13.0 0.1 0.17 12.1 0.1 1.4 1 0 0 1 1 1 0 APOBEC4 MTHFR PF02219.17 CRK24872.1 - 9.8e-42 143.2 0.0 1.1e-41 143.1 0.0 1.0 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Glyco_hydro_12 PF01670.16 CRK24883.1 - 3.5e-05 23.9 1.1 4.4e-05 23.6 1.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 GIT_SHD PF08518.11 CRK24885.1 - 1.6e-21 75.6 5.5 6.1e-10 38.6 0.1 2.7 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT PSII_Pbs27 PF13326.6 CRK24885.1 - 0.093 13.0 4.0 0.33 11.3 0.3 2.8 2 0 0 2 2 2 0 Photosystem II Pbs27 Spc7 PF08317.11 CRK24885.1 - 0.11 11.3 32.3 0.011 14.7 16.2 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein THP2 PF09432.10 CRK24885.1 - 0.83 9.7 7.2 0.25 11.4 2.9 2.3 1 1 1 2 2 2 0 Tho complex subunit THP2 CSN5_C PF18323.1 CRK24885.1 - 2.9 8.9 10.7 6.6 7.7 1.6 3.2 2 0 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain CLZ PF16526.5 CRK24885.1 - 3.4 8.1 15.5 0.35 11.2 0.4 4.6 3 1 0 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels MARVEL PF01284.23 CRK24886.1 - 5.5e-08 33.0 15.7 7e-08 32.6 15.7 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF2157 PF09925.9 CRK24886.1 - 0.0066 16.2 8.2 0.0094 15.7 8.2 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2157) Holin_SPP1 PF04688.13 CRK24886.1 - 0.2 11.8 2.2 0.43 10.8 2.2 1.5 1 0 0 1 1 1 0 SPP1 phage holin YpmT PF17431.2 CRK24886.1 - 0.76 9.9 5.5 0.17 11.9 2.0 1.8 2 0 0 2 2 2 0 Uncharacterized YmpT-like PIG-P PF08510.12 CRK24886.1 - 2.1 8.3 8.4 3.6 7.5 8.4 1.4 1 0 0 1 1 1 0 PIG-P Arteri_Gl PF00951.18 CRK24886.1 - 3.4 7.4 12.7 1 9.1 8.8 1.9 1 1 1 2 2 2 0 Arterivirus GL envelope glycoprotein Fungal_trans PF04082.18 CRK24887.1 - 5.5e-09 35.4 0.3 1.2e-08 34.4 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF3395 PF11875.8 CRK24888.1 - 1.4e-19 70.5 0.0 2.6e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 CRK24888.1 - 2.1e-05 24.5 0.1 3.9e-05 23.7 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain LigD_N PF13298.6 CRK24889.1 - 1.8e-34 118.1 0.1 3.2e-34 117.4 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase Ligase (LigD) Pap_E4 PF02711.14 CRK24889.1 - 0.26 12.3 2.6 8.8 7.4 1.0 2.6 2 0 0 2 2 2 0 E4 protein eIF-3c_N PF05470.12 CRK24889.1 - 4.1 5.6 8.9 5.8 5.1 7.4 1.8 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus ABC_tran PF00005.27 CRK24890.1 - 1.9e-47 161.2 0.0 5.3e-26 91.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 CRK24890.1 - 2.7e-35 122.4 19.2 1e-24 87.7 9.6 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region WD40 PF00400.32 CRK24890.1 - 1.1e-06 29.2 8.3 0.00034 21.4 0.1 4.8 5 0 0 5 5 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK24890.1 - 1.8e-06 28.2 0.1 0.39 11.0 0.0 4.6 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain MMR_HSR1 PF01926.23 CRK24890.1 - 0.00038 20.5 0.1 0.092 12.8 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.6 CRK24890.1 - 0.00054 19.7 0.9 0.39 10.5 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CRK24890.1 - 0.0011 19.0 0.0 0.83 9.5 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase SMC_N PF02463.19 CRK24890.1 - 0.0012 18.4 0.9 2.7 7.4 0.2 3.5 2 2 0 3 3 3 1 RecF/RecN/SMC N terminal domain T2SSE PF00437.20 CRK24890.1 - 0.0015 17.7 0.0 0.54 9.3 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_23 PF13476.6 CRK24890.1 - 0.0052 17.3 2.4 0.075 13.5 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 CRK24890.1 - 0.0057 17.1 0.0 6.2 7.2 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain Dynamin_N PF00350.23 CRK24890.1 - 0.012 15.7 0.1 0.84 9.7 0.0 2.4 2 0 0 2 2 2 0 Dynamin family FAM176 PF14851.6 CRK24890.1 - 0.012 15.2 0.9 0.098 12.3 0.0 2.5 2 0 0 2 2 2 0 FAM176 family AAA_22 PF13401.6 CRK24890.1 - 0.013 15.8 0.1 5.3 7.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 CRK24890.1 - 0.018 14.8 0.3 4.8 6.9 0.0 2.9 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 CRK24890.1 - 0.035 13.7 0.0 3.6 7.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 CRK24890.1 - 0.075 13.1 4.7 1.6 8.7 0.1 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain HIRA_B PF09453.10 CRK24890.1 - 0.14 12.0 0.6 0.35 10.8 0.6 1.7 1 0 0 1 1 1 0 HIRA B motif APG6 PF04111.12 CRK24891.1 - 3.6e-69 232.3 0.0 5.4e-69 231.7 0.0 1.3 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 CRK24891.1 - 2.1e-38 131.9 16.2 2.1e-38 131.9 16.2 1.7 2 0 0 2 2 2 1 Apg6 coiled-coil region PIG-L PF02585.17 CRK24891.1 - 0.17 12.5 0.8 0.49 11.0 0.6 1.9 2 0 0 2 2 2 0 GlcNAc-PI de-N-acetylase ArAE_2_N PF10337.9 CRK24891.1 - 0.27 10.2 4.6 0.41 9.6 4.6 1.3 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal Scm3 PF10384.9 CRK24892.1 - 1.4e-21 75.9 0.9 2.6e-21 75.1 0.1 1.9 2 0 0 2 2 2 1 Centromere protein Scm3 DUF3807 PF12720.7 CRK24893.1 - 3.6e-32 112.1 0.1 6.2e-32 111.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) Pkinase PF00069.25 CRK24893.1 - 4.5e-19 68.8 0.8 5e-11 42.5 0.3 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CRK24893.1 - 3.4e-06 26.5 0.0 4.7e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3676 PF12429.8 CRK24893.1 - 0.027 14.3 0.7 0.045 13.6 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3676) DNA_pol_alpha_N PF12254.8 CRK24893.1 - 0.061 13.4 1.4 0.26 11.4 1.4 2.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal Kri1 PF05178.12 CRK24893.1 - 0.19 12.3 4.4 1.8 9.2 0.0 2.7 2 0 0 2 2 2 0 KRI1-like family Atg14 PF10186.9 CRK24894.1 - 2e-72 244.0 0.0 2.4e-72 243.7 0.0 1.0 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 MASE3 PF17159.4 CRK24894.1 - 0.04 13.5 0.0 0.061 12.9 0.0 1.2 1 0 0 1 1 1 0 Membrane-associated sensor domain Spc7_N PF15402.6 CRK24896.1 - 1.6e-185 619.1 107.5 3.6e-99 333.4 67.0 3.7 1 1 1 2 2 2 2 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.11 CRK24896.1 - 4.7e-124 413.3 5.6 4.7e-124 413.3 5.6 2.0 3 0 0 3 3 3 1 Spc7 kinetochore protein Spc7_C2 PF15577.6 CRK24896.1 - 6.8e-21 74.1 0.2 1.3e-20 73.3 0.2 1.5 1 0 0 1 1 1 1 Spc7_C2 Fez1 PF06818.15 CRK24896.1 - 0.0046 17.4 0.7 0.0046 17.4 0.7 3.6 3 1 0 3 3 3 1 Fez1 COG2 PF06148.11 CRK24896.1 - 0.2 11.7 1.5 0.76 9.9 1.5 2.0 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Sec3_C_2 PF15278.6 CRK24896.1 - 0.28 11.6 1.1 4.1 7.8 0.2 2.7 2 0 0 2 2 2 0 Sec3 exocyst complex subunit Seryl_tRNA_N PF02403.22 CRK24896.1 - 7.3 6.9 13.2 0.096 12.9 3.7 2.9 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Ribosomal_S17_N PF16205.5 CRK24897.1 - 1e-31 109.1 1.0 1.7e-31 108.4 1.0 1.4 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 CRK24897.1 - 4.6e-26 90.7 0.2 9.1e-26 89.8 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S17 TMF_TATA_bd PF12325.8 CRK24898.1 - 0.0093 16.2 1.2 0.033 14.4 1.2 1.9 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding DUF4201 PF13870.6 CRK24898.1 - 0.059 13.1 2.8 0.12 12.1 2.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) TPR_MLP1_2 PF07926.12 CRK24898.1 - 0.061 13.4 3.4 0.22 11.6 3.4 1.9 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein EspF PF04806.12 CRK24898.1 - 2.1 8.8 6.9 0.69 10.4 3.3 2.1 2 0 0 2 2 2 0 EspF protein repeat ZapB PF06005.12 CRK24898.1 - 2.5 8.6 6.7 0.21 12.0 0.7 2.3 2 0 0 2 2 2 0 Cell division protein ZapB LicD PF04991.13 CRK24899.1 - 3.6e-05 24.0 0.5 0.00027 21.2 0.1 2.0 1 1 1 2 2 2 1 LicD family ADK PF00406.22 CRK24900.1 - 1.2e-24 87.2 0.0 3.4e-19 69.4 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase ADK_lid PF05191.14 CRK24900.1 - 2.4e-16 59.4 0.0 4e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.6 CRK24900.1 - 5.7e-10 39.7 0.0 8.7e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CRK24900.1 - 0.014 15.5 0.3 0.024 14.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 CRK24900.1 - 0.017 15.1 0.0 0.029 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 CRK24900.1 - 0.029 14.9 0.0 0.059 13.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CRK24900.1 - 0.11 12.8 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain LETM1 PF07766.13 CRK24901.1 - 3.8e-105 351.1 1.2 4.8e-105 350.7 1.2 1.1 1 0 0 1 1 1 1 LETM1-like protein LMP PF04778.12 CRK24901.1 - 0.42 10.5 0.0 0.42 10.5 0.0 2.1 2 1 0 2 2 2 0 LMP repeated region DUF1180 PF06679.12 CRK24901.1 - 0.64 10.4 4.6 1.2 9.6 4.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Glyco_hydro_28 PF00295.17 CRK24903.1 - 2.6e-05 23.4 0.1 3.3e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Ribosomal_S25 PF03297.15 CRK24927.1 - 2.4e-27 95.1 0.5 2.7e-27 94.9 0.5 1.0 1 0 0 1 1 1 1 S25 ribosomal protein MarR_2 PF12802.7 CRK24927.1 - 0.00017 21.4 0.1 0.00019 21.2 0.1 1.2 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 CRK24927.1 - 0.0036 16.8 0.1 0.0044 16.5 0.1 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR PF01047.22 CRK24927.1 - 0.011 15.6 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 MarR family Rrf2 PF02082.20 CRK24927.1 - 0.027 14.8 0.0 0.033 14.5 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator HTH_DeoR PF08220.12 CRK24927.1 - 0.04 13.7 0.0 0.056 13.2 0.0 1.2 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_27 PF13463.6 CRK24927.1 - 0.048 14.2 0.0 0.076 13.5 0.0 1.4 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_11 PF08279.12 CRK24927.1 - 0.12 12.4 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 HTH domain Sec63 PF02889.16 CRK24930.1 - 1.5e-33 116.0 0.2 2e-33 115.6 0.2 1.2 1 0 0 1 1 1 1 Sec63 Brl domain RNA_pol_3_Rpc31 PF11705.8 CRK24932.1 - 0.24 11.7 0.5 0.48 10.6 0.5 1.4 1 1 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 zf-C2H2 PF00096.26 CRK24933.1 - 1.7e-07 31.3 13.4 0.00012 22.3 1.5 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type Zn_clus PF00172.18 CRK24933.1 - 6e-05 23.1 11.3 6e-05 23.1 11.3 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-H2C2_2 PF13465.6 CRK24933.1 - 0.0016 18.8 1.7 0.0016 18.8 1.7 3.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 CRK24933.1 - 0.038 14.8 1.2 0.038 14.8 1.2 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CRK24933.1 - 0.076 13.3 3.0 0.73 10.2 0.6 2.7 1 1 1 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 CRK24933.1 - 0.54 10.2 4.1 0.23 11.4 0.2 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-BED PF02892.15 CRK24933.1 - 2.3 8.3 4.9 7.1 6.7 4.9 1.8 1 0 0 1 1 1 0 BED zinc finger zf-met PF12874.7 CRK24933.1 - 4.3 7.9 6.5 27 5.3 0.2 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 CRK24933.1 - 7.5 6.4 7.0 31 4.4 0.1 2.8 2 0 0 2 2 2 0 zinc-finger C2H2-type DZR PF12773.7 CRK24933.1 - 8.5 6.5 15.0 0.095 12.7 1.3 2.6 2 0 0 2 2 2 0 Double zinc ribbon Glyco_transf_8 PF01501.20 CRK24934.1 - 3.2e-13 49.8 0.0 5.8e-13 49.0 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 8 DHDPS PF00701.22 CRK24935.1 - 4.6e-05 22.3 0.0 7.1e-05 21.7 0.0 1.3 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family ATG2_CAD PF13329.6 CRK24936.1 - 2.5e-50 170.2 0.5 7.5e-50 168.7 0.3 2.0 2 0 0 2 2 2 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.11 CRK24936.1 - 8.2e-31 106.2 0.1 1.5e-29 102.2 0.0 3.2 4 0 0 4 4 4 1 Autophagy-related protein C terminal domain Chorein_N PF12624.7 CRK24936.1 - 4.9e-06 26.6 0.0 1.6e-05 25.0 0.0 1.9 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 Amino_oxidase PF01593.24 CRK24937.1 - 2.7e-47 162.1 0.1 1e-46 160.2 0.1 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CRK24937.1 - 5.4e-16 58.6 0.1 1.1e-15 57.6 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CRK24937.1 - 3.7e-07 29.7 0.1 9.8e-06 25.0 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CRK24937.1 - 4.3e-06 26.6 1.1 2.3e-05 24.1 0.5 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CRK24937.1 - 6e-06 25.6 0.6 0.00012 21.3 0.7 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 CRK24937.1 - 8e-06 25.9 0.1 0.0072 16.3 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox PF00070.27 CRK24937.1 - 1.2e-05 25.8 0.2 2.8e-05 24.6 0.1 1.6 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CRK24937.1 - 1.8e-05 23.6 0.2 0.0003 19.6 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 CRK24937.1 - 0.00036 19.9 0.6 0.00052 19.4 0.6 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 CRK24937.1 - 0.0028 17.1 1.0 0.0084 15.5 1.2 1.7 1 1 1 2 2 2 1 FAD dependent oxidoreductase 3HCDH_N PF02737.18 CRK24937.1 - 0.0036 17.2 0.1 0.0058 16.5 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 CRK24937.1 - 0.0045 16.1 0.1 0.0068 15.5 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.17 CRK24937.1 - 0.024 13.9 0.0 0.041 13.1 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 CRK24937.1 - 0.037 13.1 0.2 0.056 12.5 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 CRK24937.1 - 0.078 12.3 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Acyl-CoA_dh_1 PF00441.24 CRK24939.1 - 6.3e-34 117.3 0.4 1e-33 116.7 0.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 CRK24939.1 - 2.5e-18 66.0 0.1 5.7e-18 64.8 0.1 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 CRK24939.1 - 3.2e-17 62.5 0.6 5.7e-17 61.7 0.6 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 CRK24939.1 - 7e-11 42.8 0.1 2.8e-10 40.8 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 CRK24939.1 - 6.9e-05 23.1 0.0 0.00017 21.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain zf-CCHC PF00098.23 CRK24940.1 - 4.8e-58 190.8 65.5 4.1e-09 36.1 4.5 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 CRK24940.1 - 1.7e-15 56.5 37.6 0.00016 21.3 0.3 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.6 CRK24940.1 - 1.6e-12 47.2 45.3 0.026 14.5 0.9 7.1 3 2 4 7 7 7 7 Zinc knuckle zf-CCHC_6 PF15288.6 CRK24940.1 - 2.8e-06 27.0 54.7 0.0086 15.9 0.7 6.9 6 1 1 7 7 7 5 Zinc knuckle zf-CCHC_5 PF14787.6 CRK24940.1 - 0.009 15.7 44.6 0.93 9.3 1.2 7.1 5 2 2 7 7 7 5 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 CRK24940.1 - 0.025 14.4 2.4 0.025 14.4 2.4 7.4 7 0 0 7 7 7 0 Zinc knuckle UCH PF00443.29 CRK24941.1 - 6.2e-58 196.3 0.0 3.3e-44 151.3 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase SAE2 PF08573.10 CRK24941.1 - 6e-24 85.3 0.0 6e-24 85.3 0.0 3.5 3 0 0 3 3 3 1 DNA repair protein endonuclease SAE2/CtIP C-terminus UCH_1 PF13423.6 CRK24941.1 - 9.2e-16 58.3 0.0 8.2e-07 28.9 0.0 3.4 3 0 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase DUF952 PF06108.12 CRK24941.1 - 3.1e-09 36.7 0.0 7.3e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF952) HrpB7 PF09486.10 CRK24941.1 - 0.008 16.6 1.6 0.008 16.6 1.6 3.3 3 0 0 3 3 3 1 Bacterial type III secretion protein (HrpB7) ABC_tran_CTD PF16326.5 CRK24941.1 - 0.028 14.7 0.6 0.16 12.2 0.6 2.4 1 0 0 1 1 1 0 ABC transporter C-terminal domain Trimer_CC PF08954.11 CRK24941.1 - 0.68 9.5 4.7 5.9 6.5 0.8 3.5 2 0 0 2 2 2 0 Trimerisation motif AAA_13 PF13166.6 CRK24941.1 - 0.78 8.3 2.6 1.3 7.5 2.6 1.3 1 0 0 1 1 1 0 AAA domain CLZ PF16526.5 CRK24941.1 - 9.7 6.6 13.0 0.62 10.5 2.2 3.4 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ADH_zinc_N PF00107.26 CRK24943.1 - 6.2e-19 68.3 1.1 1.2e-18 67.4 1.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CRK24943.1 - 7.5e-14 51.5 0.1 1.7e-13 50.4 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Sacchrp_dh_NADP PF03435.18 CRK24943.1 - 0.023 14.9 0.2 0.047 13.9 0.2 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ADH_zinc_N_2 PF13602.6 CRK24943.1 - 0.059 14.4 0.0 0.12 13.5 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.14 CRK24943.1 - 0.084 12.4 0.2 0.16 11.5 0.2 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain zf-AN1 PF01428.16 CRK24944.1 - 1.6e-12 47.4 4.3 1.6e-12 47.4 4.3 1.6 1 1 0 1 1 1 1 AN1-like Zinc finger Transp_Tc5_C PF04236.15 CRK24944.1 - 0.44 10.9 6.2 0.19 12.1 4.1 1.5 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain HhH-GPD PF00730.25 CRK24945.1 - 6.5e-18 65.2 0.0 1e-17 64.5 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 CRK24945.1 - 9e-08 31.6 0.0 2.3e-07 30.4 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif adh_short_C2 PF13561.6 CRK24946.1 - 2e-46 158.5 0.7 2.6e-41 141.7 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRK24946.1 - 6.1e-43 146.6 0.1 8e-43 146.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CRK24946.1 - 2.8e-14 53.4 0.1 3.9e-14 53.0 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CRK24946.1 - 6.7e-05 22.5 0.3 0.00039 19.9 0.3 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family CPP1-like PF11833.8 CRK24947.1 - 0.031 14.0 1.0 0.037 13.7 1.0 1.1 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF2298 PF10060.9 CRK24947.1 - 0.6 8.8 4.5 0.71 8.5 4.5 1.0 1 0 0 1 1 1 0 Uncharacterized membrane protein (DUF2298) Med11 PF10280.9 CRK24948.1 - 0.058 13.8 0.8 0.28 11.6 0.2 2.2 2 0 0 2 2 2 0 Mediator complex protein DUF4646 PF15496.6 CRK24948.1 - 0.083 13.5 2.4 0.18 12.4 0.6 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4646) DUF1993 PF09351.10 CRK24948.1 - 0.44 10.7 1.2 10 6.2 0.2 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF1993) IF-2B PF01008.17 CRK24949.1 - 0.17 11.1 0.0 0.19 10.9 0.0 1.1 1 0 0 1 1 1 0 Initiation factor 2 subunit family NIF PF03031.18 CRK24950.1 - 2.4e-56 189.9 0.0 3e-56 189.5 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF1761 PF08570.10 CRK24951.1 - 1.6e-25 89.8 4.4 1.8e-25 89.6 4.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) Bac_export_2 PF01312.19 CRK24951.1 - 0.14 11.4 0.1 0.16 11.1 0.1 1.1 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family FAD_binding_3 PF01494.19 CRK24961.1 - 1.4e-10 41.0 0.1 1.7e-10 40.7 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain LAMTOR PF15454.6 CRK24980.1 - 0.028 15.0 0.1 0.047 14.3 0.1 1.3 1 0 0 1 1 1 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator MinC_N PF05209.13 CRK24980.1 - 0.029 14.3 0.0 0.032 14.2 0.0 1.2 1 0 0 1 1 1 0 Septum formation inhibitor MinC, N-terminal domain FbpA PF05833.11 CRK24983.1 - 2.8e-17 62.6 0.0 3.4e-17 62.4 0.0 1.0 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) SGL PF08450.12 CRK24985.1 - 4.6e-25 88.6 0.3 6.3e-25 88.2 0.1 1.3 2 0 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region DUF5074 PF16819.5 CRK24985.1 - 0.034 14.2 0.1 0.1 12.6 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5074) Phytase-like PF13449.6 CRK24985.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.3 1 1 0 1 1 1 0 Esterase-like activity of phytase FMN_dh PF01070.18 CRK24986.1 - 7.4e-107 357.4 0.0 8.4e-107 357.2 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 CRK24986.1 - 0.00069 18.7 0.5 0.0011 18.1 0.5 1.2 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 CRK24986.1 - 0.014 14.5 0.2 0.021 14.0 0.2 1.1 1 0 0 1 1 1 0 Conserved region in glutamate synthase Amidohydro_2 PF04909.14 CRK24986.1 - 0.017 14.9 0.2 1.5 8.5 0.0 2.9 2 1 1 3 3 3 0 Amidohydrolase His_biosynth PF00977.21 CRK24986.1 - 0.026 14.0 0.5 0.14 11.6 0.3 1.9 1 1 1 2 2 2 0 Histidine biosynthesis protein Casc1_N PF15927.5 CRK24987.1 - 0.45 10.2 7.3 0.76 9.4 7.3 1.3 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus TPR_14 PF13428.6 CRK24989.1 - 2.9e-07 30.7 14.5 0.16 12.9 0.1 7.5 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 CRK24989.1 - 1.3e-06 28.8 0.4 0.77 10.3 0.1 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CRK24989.1 - 6.6e-06 25.8 8.3 3.5 8.0 0.0 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 CRK24989.1 - 0.0029 17.7 0.5 2.6 8.5 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 CRK24989.1 - 0.0061 16.8 6.5 2.7 8.4 0.1 6.1 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 CRK24989.1 - 0.0072 16.6 1.0 7.7 7.1 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CRK24989.1 - 0.012 15.8 0.6 1 9.6 0.1 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 CRK24989.1 - 0.021 14.8 2.1 40 4.5 0.0 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 CRK24989.1 - 0.1 13.3 17.5 2.3 8.9 0.0 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 CRK24989.1 - 0.16 12.6 2.5 84 4.2 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 CRK24989.1 - 1.5 9.6 3.2 1.2e+02 3.7 0.0 4.3 4 0 0 4 4 3 0 Tetratricopeptide repeat RIX1 PF08167.12 CRK24990.1 - 2e-61 207.1 0.0 4.4e-61 205.9 0.0 1.6 1 0 0 1 1 1 1 rRNA processing/ribosome biogenesis WW PF00397.26 CRK24991.1 - 2.1e-07 30.9 2.9 2.1e-07 30.9 2.9 1.8 2 0 0 2 2 2 1 WW domain WRW PF10206.9 CRK24991.1 - 0.019 15.4 0.2 0.037 14.4 0.2 1.4 1 0 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f Glyco_hydro_16 PF00722.21 CRK24993.1 - 2.7e-09 36.8 1.1 2.7e-09 36.8 1.1 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Maf_N PF08383.11 CRK24994.1 - 0.08 12.7 0.2 0.17 11.7 0.2 1.5 1 0 0 1 1 1 0 Maf N-terminal region Cutinase PF01083.22 CRK24995.1 - 5.3e-42 143.8 0.0 6.5e-42 143.5 0.0 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 CRK24995.1 - 0.0078 15.8 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_6 PF12697.7 CRK24995.1 - 0.033 14.8 0.1 0.039 14.6 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CRK24995.1 - 0.085 12.1 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 MFS_1 PF07690.16 CRK24996.1 - 2.6e-10 39.8 58.1 2.6e-10 39.8 25.7 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily DIT1_PvcA PF05141.12 CRK24997.1 - 8.9e-75 251.7 0.0 1.6e-73 247.6 0.0 2.5 1 1 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein AMP-binding PF00501.28 CRK24997.1 - 1.5e-25 89.7 0.0 2.6e-25 88.9 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 CRK24997.1 - 4.5e-08 33.3 0.0 1.1e-07 32.1 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Transferase PF02458.15 CRK24997.1 - 1.5e-07 30.5 0.0 4.4e-05 22.3 0.0 3.0 2 1 0 2 2 2 1 Transferase family AATase PF07247.12 CRK24998.1 - 2.4e-10 39.6 0.0 7e-06 24.9 0.0 3.0 3 0 0 3 3 3 2 Alcohol acetyltransferase Condensation PF00668.20 CRK24998.1 - 0.014 14.1 0.0 0.024 13.3 0.0 1.2 1 0 0 1 1 1 0 Condensation domain Abhydrolase_3 PF07859.13 CRK24999.1 - 3.8e-27 95.5 0.6 5.9e-27 94.9 0.6 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 CRK24999.1 - 3e-08 33.0 0.1 6.9e-08 31.8 0.1 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 CRK24999.1 - 0.16 12.5 2.6 0.24 12.0 2.6 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family MFS_1 PF07690.16 CRK25000.1 - 7.1e-19 67.9 59.4 1.2e-16 60.6 58.2 2.7 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 CRK25000.1 - 4.6e-09 35.2 29.5 6.3e-09 34.8 29.5 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Orf78 PF06024.12 CRK25000.1 - 0.044 14.1 1.6 0.32 11.3 0.1 2.6 2 0 0 2 2 2 0 Orf78 (ac78) TTc_toxin_rep PF18807.1 CRK25000.1 - 0.17 11.8 0.5 0.38 10.6 0.5 1.5 1 0 0 1 1 1 0 Tripartite Tc toxins repeat GP41 PF00517.17 CRK25000.1 - 0.27 11.1 5.2 0.22 11.4 0.2 2.6 2 0 0 2 2 2 0 Retroviral envelope protein Sec62 PF03839.16 CRK25000.1 - 1.4 8.3 4.5 0.88 9.0 2.0 1.8 2 0 0 2 2 2 0 Translocation protein Sec62 ADC PF06314.11 CRK25001.1 - 1.4e-15 57.6 0.3 2.9e-15 56.5 0.0 1.6 2 0 0 2 2 2 1 Acetoacetate decarboxylase (ADC) FAD_binding_3 PF01494.19 CRK25001.1 - 1.6e-14 54.0 0.2 7.1e-14 51.8 0.2 2.0 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 CRK25001.1 - 3.8e-08 32.9 1.2 2.7e-06 26.8 0.2 2.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CRK25001.1 - 1.5e-06 28.4 1.0 3.7e-06 27.1 1.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CRK25001.1 - 1.8e-05 24.5 3.1 0.00011 22.0 2.2 2.0 1 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CRK25001.1 - 3.1e-05 23.3 2.3 5.1e-05 22.5 2.3 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 CRK25001.1 - 0.00028 21.4 0.8 0.0041 17.6 0.3 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 CRK25001.1 - 0.00044 19.2 0.1 0.013 14.3 0.1 2.3 2 0 0 2 2 2 1 Tryptophan halogenase FAD_oxidored PF12831.7 CRK25001.1 - 0.001 18.5 0.6 0.001 18.5 0.6 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 CRK25001.1 - 0.0011 18.2 0.0 0.0017 17.6 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Amino_oxidase PF01593.24 CRK25001.1 - 0.003 16.9 0.6 0.97 8.6 0.2 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase HI0933_like PF03486.14 CRK25001.1 - 0.0091 14.7 0.5 0.014 14.1 0.5 1.2 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 CRK25001.1 - 0.011 14.9 0.8 0.015 14.4 0.8 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A ApbA PF02558.16 CRK25001.1 - 0.019 14.6 0.9 0.035 13.8 0.9 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 CRK25001.1 - 0.057 12.7 0.0 0.09 12.0 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase LigB PF02900.18 CRK25002.1 - 6.2e-15 55.0 0.0 7.7e-15 54.7 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase PepX_C PF08530.10 CRK25003.1 - 5.3e-48 163.9 0.5 6.8e-48 163.6 0.5 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain FAA_hydrolase PF01557.18 CRK25005.1 - 5.4e-42 143.9 0.0 8.6e-42 143.3 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Peptidase_S15 PF02129.18 CRK25005.1 - 3.7e-32 112.0 0.4 5.6e-32 111.4 0.4 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) FAA_hydrolase_N PF09298.11 CRK25005.1 - 2.7e-18 66.1 0.0 5.1e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal Hydrolase_4 PF12146.8 CRK25005.1 - 0.0063 15.8 0.0 0.01 15.1 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 EF-hand_5 PF13202.6 CRK25010.1 - 0.0015 17.9 0.0 0.0036 16.7 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 CRK25010.1 - 0.0015 17.9 0.0 0.0036 16.7 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 CRK25010.1 - 0.0019 18.0 0.0 0.0057 16.5 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 CRK25010.1 - 0.0033 17.9 0.1 0.0055 17.1 0.1 1.4 1 0 0 1 1 1 1 EF-hand domain pair IF-2 PF11987.8 CRK25020.1 - 1.2e-08 35.0 0.0 2.2e-08 34.2 0.0 1.4 2 0 0 2 2 2 1 Translation-initiation factor 2 Pkinase_C PF00433.24 CRK25029.1 - 1e-05 26.1 0.4 1e-05 26.1 0.4 1.7 2 0 0 2 2 2 1 Protein kinase C terminal domain DUF2812 PF11193.8 CRK25029.1 - 0.033 14.4 1.1 0.93 9.7 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2812) Tricorn_C1 PF14684.6 CRK25029.1 - 0.11 12.6 0.9 0.34 11.0 0.1 1.8 1 1 1 2 2 2 0 Tricorn protease C1 domain NnrU PF07298.11 CRK25035.1 - 0.26 10.8 5.6 0.098 12.1 3.0 1.6 1 1 0 1 1 1 0 NnrU protein Cation_ATPase_C PF00689.21 CRK25035.1 - 3.8 7.2 18.3 2.4 7.8 13.8 2.3 1 1 2 3 3 3 0 Cation transporting ATPase, C-terminus YrzK PF17449.2 CRK25036.1 - 0.25 11.7 0.8 0.79 10.1 0.0 2.2 3 0 0 3 3 3 0 Uncharacterized YrzK-like FliN_N PF16973.5 CRK25037.1 - 0.089 12.6 0.1 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 Flagellar motor switch protein FliN N-terminal Gly-zipper_Omp PF13488.6 CRK25038.1 - 0.021 14.8 14.9 0.021 14.8 14.9 3.8 3 1 1 4 4 4 0 Glycine zipper DUF456 PF04306.13 CRK25038.1 - 0.13 12.5 23.0 0.027 14.8 9.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF456) DUF575 PF04746.12 CRK25038.1 - 0.16 12.2 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF575) Patatin PF01734.22 CRK25039.1 - 3.6e-25 89.3 0.0 7.5e-25 88.3 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase DUF1752 PF08550.10 CRK25041.1 - 2e-10 40.3 7.2 2e-10 40.3 7.2 2.3 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1752) PBP1_TM PF14812.6 CRK25041.1 - 1 9.8 5.7 4.8 7.6 3.3 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Met_10 PF02475.16 CRK25042.1 - 5.6e-23 81.7 0.0 7.1e-23 81.4 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein 2OG-FeII_Oxy_2 PF13532.6 CRK25043.1 - 3e-26 92.8 0.0 3.9e-26 92.4 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Met_10 PF02475.16 CRK25044.1 - 4.5e-48 163.6 0.0 6.4e-48 163.1 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Sec10 PF07393.11 CRK25045.1 - 4.2e-167 557.7 5.9 4.6e-167 557.5 5.9 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 Methyltransf_23 PF13489.6 CRK25045.1 - 0.12 12.2 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain RNB PF00773.19 CRK25046.1 - 1.5e-55 188.8 0.0 2.2e-55 188.3 0.0 1.2 1 0 0 1 1 1 1 RNB domain Cys_rich_FGFR PF00839.17 CRK25046.1 - 0.078 13.1 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Cysteine rich repeat PKS_DE PF18369.1 CRK25046.1 - 0.25 12.0 1.4 1.1 9.9 1.4 2.2 1 0 0 1 1 1 0 Polyketide synthase dimerisation element domain Pectate_lyase_3 PF12708.7 CRK25047.1 - 6.4e-96 320.3 7.8 3.8e-83 278.6 2.3 2.7 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 CRK25047.1 - 5.8e-08 32.3 2.3 0.0022 17.6 0.1 2.6 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase DNase_NucA_NucB PF14040.6 CRK25047.1 - 0.0036 17.7 2.1 0.01 16.2 0.1 2.6 2 0 0 2 2 2 1 Deoxyribonuclease NucA/NucB Hormone_4 PF00220.17 CRK25047.1 - 1.3 9.1 7.4 18 5.6 0.3 3.8 3 0 0 3 3 3 0 Neurohypophysial hormones, N-terminal Domain Glyco_hydro_10 PF00331.20 CRK25054.1 - 6.1e-14 51.9 0.0 6.3e-14 51.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Hydrolase PF00702.26 CRK25073.1 - 0.01 16.1 0.0 0.01 16.1 0.0 1.0 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DRMBL PF07522.14 CRK25075.1 - 4.6e-17 62.2 0.0 6e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase RMMBL PF07521.12 CRK25075.1 - 0.074 13.0 0.0 0.13 12.2 0.0 1.5 1 1 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain Pkinase PF00069.25 CRK25076.1 - 3.4e-27 95.5 0.0 3.9e-27 95.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK25076.1 - 2.9e-13 49.7 0.0 3.1e-13 49.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CRK25076.1 - 2.8e-05 23.6 0.0 3.7e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CRK25076.1 - 2.8e-05 24.2 0.3 0.014 15.3 0.5 2.0 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 CRK25076.1 - 0.0045 16.4 0.0 0.0055 16.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 CRK25076.1 - 0.0051 15.9 0.1 0.0066 15.5 0.1 1.1 1 0 0 1 1 1 1 Seadornavirus VP7 RIO1 PF01163.22 CRK25076.1 - 0.0097 15.5 0.0 0.013 15.2 0.0 1.1 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 CRK25076.1 - 0.2 10.4 1.9 0.2 10.4 0.3 1.6 2 0 0 2 2 2 0 Fungal protein kinase Haspin_kinase PF12330.8 CRK25076.1 - 0.2 10.5 0.8 0.27 10.1 0.8 1.2 1 0 0 1 1 1 0 Haspin like kinase domain HRXXH PF13933.6 CRK25078.1 - 7.6e-101 336.8 0.0 1e-100 336.3 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Aspzincin_M35 PF14521.6 CRK25078.1 - 2.3e-05 25.0 0.0 4.6e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase ArdA PF07275.11 CRK25078.1 - 0.12 13.0 0.3 0.21 12.2 0.3 1.4 1 1 0 1 1 1 0 Antirestriction protein (ArdA) Sporozoite_P67 PF05642.11 CRK25078.1 - 0.13 10.3 0.0 0.15 10.1 0.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen LPMO_10 PF03067.15 CRK25080.1 - 4.4e-07 30.8 1.4 8.7e-07 29.8 1.4 1.5 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Apolipoprotein PF01442.18 CRK25081.1 - 0.00073 19.5 0.6 0.0028 17.6 0.7 1.9 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain ApoO PF09769.9 CRK25081.1 - 0.0045 16.9 1.9 0.51 10.3 0.3 2.3 2 1 0 2 2 2 2 Apolipoprotein O ApoLp-III PF07464.11 CRK25081.1 - 0.011 15.8 8.7 1.5 8.9 0.1 2.8 2 1 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Baculo_PEP_C PF04513.12 CRK25081.1 - 0.016 15.3 10.8 0.52 10.3 0.4 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prominin PF05478.11 CRK25081.1 - 0.13 10.2 1.2 0.42 8.5 0.9 1.7 1 1 0 1 1 1 0 Prominin IF-2 PF11987.8 CRK25081.1 - 0.13 12.4 5.5 0.3 11.2 1.3 2.9 1 1 1 3 3 3 0 Translation-initiation factor 2 V-ATPase_G PF03179.15 CRK25081.1 - 0.15 12.6 2.6 0.81 10.3 0.8 2.5 1 1 2 3 3 3 0 Vacuolar (H+)-ATPase G subunit Allexi_40kDa PF05549.11 CRK25081.1 - 0.18 11.3 0.1 7.5 6.0 0.0 2.0 2 0 0 2 2 2 0 Allexivirus 40kDa protein Gp-FAR-1 PF05823.12 CRK25081.1 - 0.22 11.9 1.2 1.1 9.7 0.7 2.1 1 1 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) HisKA_3 PF07730.13 CRK25081.1 - 0.54 10.8 4.4 12 6.5 0.6 3.5 2 1 1 3 3 3 0 Histidine kinase Lyase_1 PF00206.20 CRK25081.1 - 0.71 9.2 8.8 0.52 9.7 5.9 1.8 1 1 1 2 2 2 0 Lyase T7SS_ESX_EspC PF10824.8 CRK25081.1 - 2.4 8.7 12.8 3.1 8.3 0.9 2.9 1 1 2 3 3 3 0 Excreted virulence factor EspC, type VII ESX diderm HET PF06985.11 CRK25082.1 - 6.3e-34 117.4 0.6 9.7e-34 116.8 0.6 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Nuc_deoxyri_tr2 PF15891.5 CRK25082.1 - 0.1 12.9 0.0 0.25 11.7 0.0 1.6 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase like Vint PF14623.6 CRK25082.1 - 0.14 11.9 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Hint-domain MFS_1 PF07690.16 CRK25083.1 - 2.4e-14 53.0 21.7 4.8e-12 45.5 20.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.16 CRK25083.1 - 8.5e-07 28.8 2.3 8.5e-07 28.8 2.3 1.9 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 TMEM100 PF16311.5 CRK25084.1 - 0.062 12.9 0.4 0.062 12.9 0.4 1.8 2 0 0 2 2 2 0 Transmembrane protein 100 Inhibitor_I78 PF11720.8 CRK25085.1 - 9.3e-10 38.4 0.0 1.3e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.18 CRK25085.1 - 0.00062 20.4 0.1 0.001 19.7 0.1 1.3 1 0 0 1 1 1 1 Potato inhibitor I family DUF2924 PF11149.8 CRK25085.1 - 0.04 14.3 0.0 0.048 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2924) BTB PF00651.31 CRK25087.1 - 1.6e-05 25.1 0.1 3.8e-05 23.9 0.1 1.6 1 0 0 1 1 1 1 BTB/POZ domain DUF3435 PF11917.8 CRK25088.1 - 5.7e-65 219.9 0.1 7.6e-65 219.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) OTT_1508_deam PF14441.6 CRK25090.1 - 2.2e-11 43.6 0.0 5.5e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 OTT_1508-like deaminase RVT_3 PF13456.6 CRK25091.1 - 0.00043 20.1 0.0 0.0013 18.6 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase-like Golgin_A5 PF09787.9 CRK25091.1 - 0.0036 16.8 3.0 0.0097 15.4 3.0 1.7 1 1 0 1 1 1 1 Golgin subfamily A member 5 Spc7 PF08317.11 CRK25091.1 - 0.015 14.2 1.4 0.027 13.3 1.4 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 CRK25091.1 - 0.016 15.3 3.4 0.048 13.7 3.4 1.8 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein TMF_TATA_bd PF12325.8 CRK25091.1 - 0.11 12.7 3.9 0.16 12.2 2.1 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding ADIP PF11559.8 CRK25091.1 - 0.11 12.5 2.2 0.34 11.0 2.2 1.9 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding IFT57 PF10498.9 CRK25091.1 - 0.12 11.3 2.4 0.24 10.4 2.4 1.5 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF1664 PF07889.12 CRK25091.1 - 0.13 12.3 1.9 0.3 11.1 1.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) ATG16 PF08614.11 CRK25091.1 - 0.89 9.7 13.3 0.2 11.9 8.5 2.4 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Seryl_tRNA_N PF02403.22 CRK25091.1 - 1.1 9.6 4.9 2.1 8.6 1.1 3.1 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Fez1 PF06818.15 CRK25091.1 - 1.2 9.6 6.2 0.81 10.1 3.1 2.2 1 1 0 2 2 2 0 Fez1 ABC_tran_CTD PF16326.5 CRK25091.1 - 1.4 9.2 7.1 0.84 9.9 0.1 3.4 3 1 1 4 4 3 0 ABC transporter C-terminal domain PSK PF06404.12 CRK25091.1 - 8 7.6 6.9 2.4 9.3 0.1 3.3 2 1 0 2 2 2 0 Phytosulfokine precursor protein (PSK) Pkinase PF00069.25 CRK25095.1 - 8.6e-07 28.6 0.0 1.6e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 CRK25095.1 - 1.2e-06 28.0 0.0 2.3e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Radial_spoke_3 PF06098.11 CRK25095.1 - 0.0001 21.7 10.2 0.00021 20.7 10.2 1.4 1 0 0 1 1 1 1 Radial spoke protein 3 ARGLU PF15346.6 CRK25095.1 - 0.0064 16.4 22.3 0.012 15.5 22.3 1.3 1 0 0 1 1 1 1 Arginine and glutamate-rich 1 HSDR_N_2 PF13588.6 CRK25095.1 - 0.021 14.8 0.0 4.9 7.2 0.0 2.4 2 0 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) APH PF01636.23 CRK25095.1 - 0.022 14.7 4.7 0.034 14.1 0.0 2.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 CRK25095.1 - 0.17 11.5 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF5401 PF17380.2 CRK25095.1 - 1.4 6.9 14.9 2.4 6.1 14.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Asp-B-Hydro_N PF05279.11 CRK25095.1 - 2 8.4 5.2 3.4 7.7 5.2 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region U79_P34 PF03064.16 CRK25095.1 - 2.6 7.4 6.3 4.4 6.6 6.3 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DDRGK PF09756.9 CRK25095.1 - 4.5 6.8 14.3 7.4 6.1 14.3 1.3 1 0 0 1 1 1 0 DDRGK domain RF-1 PF00472.20 CRK25098.1 - 0.0019 18.1 1.1 0.0025 17.8 1.1 1.2 1 0 0 1 1 1 1 RF-1 domain DUF1912 PF08930.10 CRK25098.1 - 0.036 14.2 0.0 0.061 13.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1912) RNA_pol_Rpb1_7 PF04990.12 CRK25112.1 - 5e-20 71.9 0.4 7.6e-20 71.3 0.4 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RCDG1 PF15725.5 CRK25119.1 - 0.82 10.1 9.8 0.84 10.1 9.8 1.0 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein PAP2 PF01569.21 CRK25120.1 - 0.00097 18.9 4.3 0.011 15.5 3.3 2.5 1 1 1 2 2 2 1 PAP2 superfamily DUF212 PF02681.14 CRK25120.1 - 0.039 14.1 0.0 0.064 13.4 0.0 1.4 1 1 0 1 1 1 0 Divergent PAP2 family VapB_antitoxin PF09957.9 CRK25120.1 - 0.17 11.8 0.0 0.22 11.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial antitoxin of type II TA system, VapB DEAD PF00270.29 CRK25121.1 - 1.7e-13 50.7 0.0 2.9e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Kelch_5 PF13854.6 CRK25121.1 - 2.6e-05 24.1 0.8 7e-05 22.7 0.1 1.9 2 0 0 2 2 2 1 Kelch motif Kelch_6 PF13964.6 CRK25121.1 - 0.0002 21.5 0.1 0.066 13.5 0.1 2.3 2 0 0 2 2 2 1 Kelch motif Kelch_2 PF07646.15 CRK25121.1 - 0.0033 17.3 1.0 0.018 15.0 0.2 2.2 2 0 0 2 2 2 1 Kelch motif Kelch_1 PF01344.25 CRK25121.1 - 0.0053 16.3 0.2 0.0092 15.6 0.2 1.4 1 0 0 1 1 1 1 Kelch motif ResIII PF04851.15 CRK25121.1 - 0.055 13.5 0.0 0.091 12.8 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Kelch_3 PF13415.6 CRK25121.1 - 0.082 13.2 0.4 2.7 8.4 0.0 2.4 2 0 0 2 2 2 0 Galactose oxidase, central domain T4SS-DNA_transf PF02534.14 CRK25121.1 - 0.13 11.1 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer Kinesin PF00225.23 CRK25122.1 - 7.3e-108 360.4 0.1 7.3e-108 360.4 0.1 1.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CRK25122.1 - 7.7e-24 84.3 0.2 3.2e-23 82.3 0.0 2.2 2 0 0 2 2 2 1 Microtubule binding Microtub_bind PF13931.6 CRK25122.1 - 2.3e-07 31.2 0.3 2.3e-07 31.2 0.3 5.2 4 1 2 6 6 6 1 Kinesin-associated microtubule-binding DUF3567 PF12091.8 CRK25122.1 - 0.076 13.1 0.3 0.31 11.2 0.3 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3567) Focal_AT PF03623.13 CRK25122.1 - 0.95 9.5 16.4 0.2 11.7 0.9 3.8 2 1 1 3 3 3 0 Focal adhesion targeting region RRN9 PF10680.9 CRK25123.1 - 9.9e-14 51.4 0.2 1e-12 48.2 0.2 2.9 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor zf-C2H2_aberr PF17017.5 CRK25123.1 - 0.0047 17.1 1.7 0.077 13.1 2.0 2.2 1 1 1 2 2 2 1 Aberrant zinc-finger zf-C2H2 PF00096.26 CRK25123.1 - 0.84 10.2 14.8 0.11 13.1 4.5 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type Pescadillo_N PF06732.11 CRK25124.1 - 5e-20 72.2 0.0 7.5e-11 42.1 0.0 2.4 1 1 1 2 2 2 2 Pescadillo N-terminus UDG PF03167.19 CRK25124.1 - 6.1e-10 39.3 0.0 1.3e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily BRCT PF00533.26 CRK25124.1 - 0.00076 19.8 0.0 0.002 18.5 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 CRK25124.1 - 0.18 12.2 0.0 2.4 8.6 0.0 2.3 1 1 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain Pex14_N PF04695.13 CRK25125.1 - 0.012 16.3 1.1 0.018 15.7 1.1 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3464 PF11947.8 CRK25125.1 - 0.046 13.5 0.2 0.072 12.8 0.2 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Pal1 PF08316.11 CRK25126.1 - 1.9e-07 31.9 0.0 4.7e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 Pal1 cell morphology protein COE1_HLH PF16423.5 CRK25126.1 - 0.017 14.8 0.0 0.043 13.5 0.0 1.6 1 0 0 1 1 1 0 Transcription factor COE1 helix-loop-helix domain CytochromB561_N PF09786.9 CRK25126.1 - 0.93 8.4 5.8 1.2 8.0 5.8 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal HVSL PF09749.9 CRK25127.1 - 1e-83 280.5 0.0 1.2e-83 280.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein ERO1 PF04137.15 CRK25128.1 - 3.3e-111 371.9 0.1 2.5e-109 365.7 0.0 2.4 2 1 0 2 2 2 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) PBP1_TM PF14812.6 CRK25128.1 - 0.00054 20.3 4.9 0.00054 20.3 4.9 1.9 2 0 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.12 CRK25128.1 - 0.076 12.3 9.4 0.15 11.4 9.4 1.4 1 0 0 1 1 1 0 NOA36 protein CENP-N PF05238.13 CRK25128.1 - 0.17 11.2 0.3 0.28 10.5 0.3 1.2 1 0 0 1 1 1 0 Kinetochore protein CHL4 like RRN3 PF05327.11 CRK25128.1 - 0.84 8.1 5.4 1.2 7.6 5.4 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Sporozoite_P67 PF05642.11 CRK25128.1 - 1.3 7.0 6.9 2 6.4 6.9 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2457 PF10446.9 CRK25128.1 - 1.7 7.7 17.4 2.6 7.1 17.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) FAM176 PF14851.6 CRK25128.1 - 2.2 8.0 5.9 5 6.8 5.9 1.6 1 0 0 1 1 1 0 FAM176 family DNA_pol_phi PF04931.13 CRK25128.1 - 2.4 6.2 14.9 3.5 5.6 14.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi TRAP_alpha PF03896.16 CRK25128.1 - 2.6 7.2 5.4 4.1 6.5 5.4 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CDC45 PF02724.14 CRK25128.1 - 4 5.6 10.0 5.7 5.1 10.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 CRK25128.1 - 4.3 5.4 13.2 6 5.0 13.2 1.1 1 0 0 1 1 1 0 Nop14-like family Pox_RNA_Pol_19 PF05320.12 CRK25128.1 - 4.8 7.1 6.7 11 5.9 6.7 1.5 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit CKS PF01111.19 CRK25129.1 - 1.9e-34 117.7 1.1 2.8e-34 117.2 1.1 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Bromodomain PF00439.25 CRK25130.1 - 3.3e-31 107.2 4.1 2.5e-15 56.3 0.3 2.9 3 0 0 3 3 3 2 Bromodomain Ribosomal_L12 PF00542.19 CRK25130.1 - 0.0086 16.4 2.9 4.2 7.8 0.1 2.8 3 0 0 3 3 3 2 Ribosomal protein L7/L12 C-terminal domain Hormone_6 PF00236.18 CRK25130.1 - 0.16 12.0 0.6 19 5.3 0.1 2.5 2 0 0 2 2 2 0 Glycoprotein hormone Afi1 PF07792.12 CRK25130.1 - 1.7 9.1 8.5 15 6.0 0.4 2.8 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DNA_pol_phi PF04931.13 CRK25130.1 - 9.7 4.1 17.6 16 3.4 17.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi Thg1C PF14413.6 CRK25131.1 - 3.2e-31 108.0 0.0 4.7e-31 107.5 0.0 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.12 CRK25131.1 - 4.1e-19 68.8 0.0 5.8e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase SAP130_C PF16014.5 CRK25131.1 - 0.87 8.6 9.6 0.023 13.8 3.2 1.5 2 0 0 2 2 2 0 Histone deacetylase complex subunit SAP130 C-terminus WD40 PF00400.32 CRK25132.1 - 2.4e-13 50.3 9.5 2.9e-05 24.7 0.2 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK25132.1 - 8.4e-11 42.0 1.8 0.036 14.3 0.0 5.2 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CRK25132.1 - 5.6e-06 26.4 0.2 0.071 13.0 0.0 2.8 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A RNA_pol_Rpb1_1 PF04997.12 CRK25133.1 - 3.4e-100 335.4 0.1 5.2e-100 334.8 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 CRK25133.1 - 2.8e-76 255.4 0.0 4.9e-76 254.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_5 PF04998.17 CRK25133.1 - 1.1e-60 205.4 0.0 7.8e-60 202.6 0.0 2.1 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_7 PF04990.12 CRK25133.1 - 8.9e-48 161.7 3.5 6.5e-47 158.9 4.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_3 PF04983.18 CRK25133.1 - 8.9e-46 155.7 0.0 1.9e-45 154.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 CRK25133.1 - 5.5e-37 126.0 0.1 1.3e-36 124.8 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_6 PF04992.14 CRK25133.1 - 1.4e-15 57.7 0.7 2.6e-15 56.8 0.7 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_R PF05001.13 CRK25133.1 - 0.25 11.8 205.8 0.023 15.0 6.2 14.1 9 4 4 14 14 14 0 RNA polymerase Rpb1 C-terminal repeat MCPVI PF02993.14 CRK25137.1 - 0.13 12.1 1.5 0.14 11.9 1.5 1.0 1 0 0 1 1 1 0 Minor capsid protein VI UPF0183 PF03676.14 CRK25138.1 - 1.3e-28 100.5 0.0 5e-27 95.2 0.0 2.4 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0183) UPF0183 PF03676.14 CRK25139.1 - 0.0089 15.4 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0183) Condensation PF00668.20 CRK25140.1 - 3.9e-08 32.4 0.0 4.3e-08 32.3 0.0 1.0 1 0 0 1 1 1 1 Condensation domain JmjN PF02375.17 CRK25140.1 - 0.086 12.8 0.1 0.12 12.4 0.1 1.2 1 0 0 1 1 1 0 jmjN domain ANAPC4 PF12896.7 CRK25177.1 - 1.1e-25 90.3 0.0 1.2e-25 90.2 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 TRAM1 PF08390.11 CRK25177.1 - 0.048 13.3 0.0 0.063 13.0 0.0 1.5 1 1 0 1 1 1 0 TRAM1-like protein RNA_pol_Rpb1_2 PF00623.20 CRK25179.1 - 1.8e-25 90.1 0.0 2.3e-25 89.8 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 CRK25179.1 - 4e-13 49.6 0.0 5e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 1-cysPrx_C PF10417.9 CRK25180.1 - 1.6e-12 47.1 0.2 2.9e-12 46.2 0.2 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Kelch_4 PF13418.6 CRK25181.1 - 2.6e-16 59.4 0.2 1.3e-05 25.1 0.0 4.7 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_3 PF13415.6 CRK25181.1 - 3.2e-14 52.8 4.3 5.8e-08 32.8 0.0 5.4 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.25 CRK25181.1 - 1.2e-12 47.1 0.1 0.0022 17.5 0.0 4.7 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 CRK25181.1 - 7.4e-12 45.1 3.8 0.0052 17.0 0.7 4.8 3 1 1 4 4 4 3 Kelch motif Kelch_5 PF13854.6 CRK25181.1 - 8.8e-12 44.7 5.9 2.4e-05 24.2 0.1 4.1 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 CRK25181.1 - 1.8e-07 30.8 0.3 0.0015 18.5 0.0 4.5 5 1 0 5 5 5 1 Kelch motif BTB PF00651.31 CRK25181.1 - 0.008 16.4 0.0 0.3 11.3 0.0 2.4 2 0 0 2 2 2 1 BTB/POZ domain DUF2236 PF09995.9 CRK25182.1 - 9.8e-11 42.3 0.4 1.6e-10 41.6 0.4 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Myb_DNA-binding PF00249.31 CRK25183.1 - 1.9e-07 31.2 0.2 1.6e-06 28.2 0.0 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CRK25183.1 - 5.3e-05 23.4 0.1 0.00019 21.6 0.0 1.9 1 1 1 2 2 2 1 Myb-like DNA-binding domain Rap1_C PF11626.8 CRK25183.1 - 0.02 15.0 0.0 0.04 14.0 0.0 1.5 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain UbiA PF01040.18 CRK25184.1 - 4.7e-58 196.4 26.2 4.7e-58 196.4 26.2 1.5 1 1 0 1 1 1 1 UbiA prenyltransferase family SMYLE_N PF18615.1 CRK25184.1 - 0.86 9.1 7.8 1.2 8.6 7.8 1.1 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Med3 PF11593.8 CRK25184.1 - 8.2 5.5 14.1 12 4.9 14.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal TniQ PF06527.11 CRK25185.1 - 0.27 12.0 0.0 0.27 12.0 0.0 2.9 3 1 0 3 3 3 0 TniQ zf-Di19 PF05605.12 CRK25185.1 - 3.2 8.1 14.0 3 8.2 0.5 4.0 4 0 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding DZR PF12773.7 CRK25185.1 - 3.9 7.6 23.2 0.053 13.5 0.4 4.7 4 1 2 6 6 6 0 Double zinc ribbon Oxidored_molyb PF00174.19 CRK25186.1 - 1.5e-56 190.7 0.0 2.1e-56 190.2 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 CRK25186.1 - 9.3e-27 93.7 2.7 9.5e-27 93.7 0.3 2.4 3 1 0 3 3 3 1 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.28 CRK25186.1 - 4.9e-11 42.6 0.0 8.3e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RPN2_C PF18004.1 CRK25187.1 - 1.4e-56 190.9 6.5 1.4e-56 190.9 6.5 1.9 3 0 0 3 3 3 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 CRK25187.1 - 1.8e-41 138.5 21.6 1.2e-08 35.0 0.0 8.6 8 0 0 8 8 8 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 CRK25187.1 - 2.6e-19 69.4 0.0 7.2e-14 51.9 0.0 5.4 4 1 2 6 6 6 2 HEAT repeats HEAT PF02985.22 CRK25187.1 - 1.7e-05 24.7 0.4 3.1 8.3 0.0 5.6 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.6 CRK25187.1 - 4.4e-05 23.9 0.2 0.021 15.4 0.0 4.7 3 1 1 4 4 4 2 HEAT-like repeat Cnd1 PF12717.7 CRK25187.1 - 0.0075 16.3 0.0 2.9 7.9 0.0 3.0 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 mRNA_triPase PF02940.15 CRK25188.1 - 4.3e-54 183.6 0.0 7e-54 182.9 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain AA_permease_2 PF13520.6 CRK25189.1 - 2.2e-63 214.6 23.3 7.1e-63 212.9 23.3 1.9 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CRK25189.1 - 6.3e-09 35.0 14.2 6.3e-09 35.0 14.2 3.2 3 1 0 3 3 3 1 Amino acid permease Glyco_hydro_88 PF07470.13 CRK25191.1 - 6e-06 25.6 0.2 6.7e-06 25.4 0.2 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Xan_ur_permease PF00860.20 CRK25193.1 - 7.8e-06 24.8 7.2 7.8e-06 24.8 7.2 1.3 2 0 0 2 2 2 1 Permease family ANAPC4_WD40 PF12894.7 CRK25194.1 - 0.00052 20.3 0.0 0.0027 18.0 0.0 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain Glyco_hydro_18 PF00704.28 CRK25195.1 - 1e-65 222.5 0.0 1.2e-65 222.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 GHL15 PF14885.6 CRK25195.1 - 0.08 12.9 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 15 GDPD PF03009.17 CRK25196.1 - 2.6e-13 50.3 0.0 3.7e-13 49.8 0.0 1.3 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family TFIIA PF03153.13 CRK25197.1 - 0.0027 17.8 7.3 0.004 17.2 7.3 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CRK25197.1 - 0.071 12.7 13.3 0.11 12.0 13.3 1.3 1 0 0 1 1 1 0 Spt20 family Suf PF05843.14 CRK25197.1 - 0.34 10.9 7.3 0.59 10.1 7.3 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) eIF-3_zeta PF05091.12 CRK25197.1 - 0.4 9.6 5.9 0.6 9.0 5.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Med3 PF11593.8 CRK25197.1 - 0.42 9.8 7.3 0.64 9.1 7.3 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF908 PF06012.12 CRK25197.1 - 3.6 6.9 4.5 5.7 6.3 4.5 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) SARAF PF06682.12 CRK25197.1 - 4.9 6.7 8.4 9.7 5.7 8.4 1.4 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF4834 PF16118.5 CRK25197.1 - 5.9 7.9 6.0 1.9 9.5 2.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Ribosomal_L18 PF17135.4 CRK25200.1 - 5e-42 143.4 0.2 5.4e-42 143.3 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 CRK25200.1 - 0.023 15.4 0.1 0.043 14.5 0.1 1.5 2 0 0 2 2 2 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Glyco_hydro_61 PF03443.14 CRK25203.1 - 1.3e-20 74.2 0.0 1.4e-20 74.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 p450 PF00067.22 CRK25223.1 - 9.3e-57 192.8 0.0 1.1e-56 192.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 CRK25225.1 - 1.4e-74 251.5 0.0 1.9e-55 188.5 0.0 3.0 3 0 0 3 3 3 3 Cytochrome P450 DUF5391 PF17369.2 CRK25225.1 - 0.07 13.2 0.4 15 5.7 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5391) HXXEE PF13787.6 CRK25225.1 - 0.36 11.7 4.5 12 6.8 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function with HXXEE motif CopD PF05425.13 CRK25225.1 - 0.51 10.8 5.9 9.4 6.7 0.4 2.5 2 0 0 2 2 2 0 Copper resistance protein D FixQ PF05545.11 CRK25225.1 - 0.92 9.5 5.1 12 6.0 0.9 3.0 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ Sensor PF13796.6 CRK25225.1 - 1.8 8.6 5.3 14 5.7 0.8 2.4 2 0 0 2 2 2 0 Putative sensor DUF3074 PF11274.8 CRK25226.1 - 9.4e-41 139.8 2.0 3.9e-40 137.8 0.3 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3074) GAT PF03127.14 CRK25226.1 - 0.11 12.8 2.2 0.21 11.9 2.2 1.4 1 0 0 1 1 1 0 GAT domain STAT_alpha PF01017.20 CRK25226.1 - 0.15 11.9 5.6 0.27 11.1 5.6 1.4 1 0 0 1 1 1 0 STAT protein, all-alpha domain BRE1 PF08647.11 CRK25226.1 - 0.21 11.7 6.1 0.12 12.5 3.3 1.9 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Baculo_p24 PF05073.12 CRK25226.1 - 0.23 11.2 2.2 0.37 10.6 2.2 1.2 1 0 0 1 1 1 0 Baculovirus P24 capsid protein UPF0242 PF06785.11 CRK25226.1 - 0.24 11.5 3.5 0.35 10.9 3.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Lectin_N PF03954.14 CRK25226.1 - 0.89 9.3 3.7 2 8.2 3.6 1.6 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain Sec34 PF04136.15 CRK25226.1 - 1.5 8.6 4.2 2.7 7.9 2.2 2.2 2 1 1 3 3 3 0 Sec34-like family Septin PF00735.18 CRK25227.1 - 7.5e-105 350.2 0.0 1.3e-104 349.5 0.0 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 CRK25227.1 - 0.00012 22.2 0.0 0.00034 20.7 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CRK25227.1 - 0.00036 20.5 0.1 0.0015 18.4 0.1 2.1 2 1 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 CRK25227.1 - 0.0017 18.4 2.8 0.62 10.1 0.0 3.0 2 1 1 3 3 3 2 Dynamin family Ribosomal_60s PF00428.19 CRK25227.1 - 0.048 14.2 6.0 0.11 13.1 4.9 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein AAA_22 PF13401.6 CRK25227.1 - 0.097 12.9 0.0 0.51 10.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain Ribosomal_S17e PF00833.18 CRK25227.1 - 0.1 12.5 3.0 0.24 11.3 3.0 1.6 1 0 0 1 1 1 0 Ribosomal S17 ABC_tran PF00005.27 CRK25227.1 - 0.11 13.0 0.2 0.77 10.3 0.0 2.3 2 1 0 2 2 2 0 ABC transporter AAA_23 PF13476.6 CRK25227.1 - 0.18 12.3 2.9 29 5.1 2.9 2.3 2 0 0 2 2 2 0 AAA domain DUF3138 PF11336.8 CRK25227.1 - 0.41 9.2 2.6 0.54 8.8 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Septin PF00735.18 CRK25228.1 - 2.5e-55 187.7 0.0 2.9e-55 187.6 0.0 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 CRK25228.1 - 2.7e-05 24.2 0.0 3.9e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 CRK25228.1 - 8.4e-05 22.7 0.1 0.2 11.7 0.0 2.3 1 1 1 2 2 2 2 Dynamin family RsgA_GTPase PF03193.16 CRK25228.1 - 0.00014 21.8 0.1 0.00032 20.6 0.1 1.6 1 1 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 CRK25228.1 - 0.03 14.6 0.1 0.14 12.4 0.1 1.9 1 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 CRK25228.1 - 0.099 12.8 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CRK25228.1 - 0.11 13.0 0.0 0.14 12.7 0.0 1.3 1 1 0 1 1 1 0 ABC transporter TAFII55_N PF04658.13 CRK25229.1 - 8.6e-53 178.3 0.4 2e-47 160.9 0.0 2.7 2 0 0 2 2 2 2 TAFII55 protein conserved region DUF4094 PF13334.6 CRK25229.1 - 0.35 11.3 1.3 1.2 9.6 1.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) DUF3347 PF11827.8 CRK25229.1 - 1.7 8.8 7.3 0.2 11.8 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3347) Ribosomal_L37 PF08561.10 CRK25230.1 - 1.6e-38 131.9 0.5 2.3e-38 131.4 0.5 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 CHD5 PF04420.14 CRK25230.1 - 0.087 12.7 0.6 0.15 11.9 0.6 1.3 1 0 0 1 1 1 0 CHD5-like protein RRM_1 PF00076.22 CRK25231.1 - 4e-37 125.9 0.1 1.7e-18 66.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.8 CRK25231.1 - 0.018 14.7 0.0 5.3 6.8 0.0 2.5 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated RRM_7 PF16367.5 CRK25231.1 - 0.029 14.5 0.0 2 8.6 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif Macoilin PF09726.9 CRK25231.1 - 0.14 10.7 32.4 0.19 10.3 32.4 1.2 1 0 0 1 1 1 0 Macoilin family TFIIF_alpha PF05793.12 CRK25231.1 - 3.9 6.0 71.0 7.3 5.1 71.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) stn_TNFRSF12A PF12191.8 CRK25232.1 - 0.084 13.1 0.1 0.16 12.2 0.1 1.4 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain WH2 PF02205.20 CRK25234.1 - 1.4e-07 31.1 0.9 1.4e-07 31.1 0.9 2.2 2 0 0 2 2 2 1 WH2 motif Cyt_bd_oxida_II PF02322.15 CRK25235.1 - 0.0047 16.3 2.2 0.008 15.6 2.2 1.3 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit II Saf_2TM PF18303.1 CRK25235.1 - 0.1 12.2 3.5 6.8 6.3 0.2 3.0 2 1 0 3 3 3 0 SAVED-fused 2TM effector domain Virul_fac_BrkB PF03631.15 CRK25235.1 - 1.3 8.6 6.1 2.9 7.5 5.9 1.5 1 1 0 1 1 1 0 Virulence factor BrkB CHORD PF04968.12 CRK25236.1 - 2.8e-47 159.3 18.0 1.4e-24 86.6 5.0 2.2 2 0 0 2 2 2 2 CHORD CS PF04969.16 CRK25236.1 - 1.6e-12 48.3 0.0 2.5e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 CS domain DUF836 PF05768.14 CRK25237.1 - 4.1e-12 46.3 0.0 7.3e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 CRK25237.1 - 0.00042 20.5 0.0 0.0012 19.1 0.0 1.7 2 0 0 2 2 2 1 Glutaredoxin DUF1223 PF06764.11 CRK25237.1 - 0.25 11.3 0.4 0.42 10.6 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1223) SHS2_Rpb7-N PF03876.17 CRK25238.1 - 1.3e-14 54.3 0.0 2.2e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 CRK25238.1 - 2.4e-11 43.8 0.0 3.6e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 S1 RNA binding domain DUF962 PF06127.11 CRK25239.1 - 4.1e-27 94.1 0.1 8e-27 93.2 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF962) Sigma70_r4 PF04545.16 CRK25240.1 - 0.65 9.6 2.6 4.2 7.0 0.1 2.4 2 0 0 2 2 2 0 Sigma-70, region 4 Baculo_PEP_C PF04513.12 CRK25241.1 - 0.00042 20.4 0.5 1.3 9.0 0.0 2.7 3 0 0 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_22 PF13401.6 CRK25244.1 - 1.1e-13 51.6 0.0 2.5e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CRK25244.1 - 8.4e-13 49.1 0.5 1.2e-11 45.3 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 CRK25244.1 - 1.3e-08 35.3 0.0 2.3e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 CRK25244.1 - 1.3e-05 24.7 0.0 2.2e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein AAA_19 PF13245.6 CRK25244.1 - 0.00026 21.3 0.0 0.00062 20.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CRK25244.1 - 0.0012 18.6 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 CRK25244.1 - 0.0014 18.2 0.0 0.0022 17.5 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region DUF815 PF05673.13 CRK25244.1 - 0.0014 17.9 0.0 0.0022 17.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 CRK25244.1 - 0.0014 19.2 0.1 0.0036 17.8 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_5 PF07728.14 CRK25244.1 - 0.0014 18.6 0.0 0.0039 17.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 CRK25244.1 - 0.0034 17.8 0.0 0.0071 16.7 0.0 1.5 1 0 0 1 1 1 1 RNA helicase Rad17 PF03215.15 CRK25244.1 - 0.0046 16.9 0.0 0.0071 16.3 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain SseB_C PF14581.6 CRK25244.1 - 0.0046 17.0 0.0 0.023 14.8 0.0 2.0 2 0 0 2 2 2 1 SseB protein C-terminal domain ATPase_2 PF01637.18 CRK25244.1 - 0.0065 16.4 0.0 0.016 15.1 0.0 1.7 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 CRK25244.1 - 0.0083 15.9 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 CRK25244.1 - 0.017 14.3 0.0 0.024 13.8 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_14 PF13173.6 CRK25244.1 - 0.02 14.9 0.0 0.037 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 CRK25244.1 - 0.022 14.6 0.1 0.052 13.3 0.0 1.6 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 CRK25244.1 - 0.023 13.9 0.0 0.034 13.4 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain NTPase_1 PF03266.15 CRK25244.1 - 0.026 14.4 0.4 0.058 13.3 0.1 1.6 1 1 0 2 2 2 0 NTPase NACHT PF05729.12 CRK25244.1 - 0.052 13.5 0.0 0.089 12.7 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 CRK25244.1 - 0.088 13.0 0.0 0.23 11.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain DAP3 PF10236.9 CRK25244.1 - 0.1 11.7 0.0 12 5.0 0.0 2.2 1 1 1 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_2 PF07724.14 CRK25244.1 - 0.13 12.4 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) DUF2075 PF09848.9 CRK25244.1 - 0.16 11.2 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PhageMin_Tail PF10145.9 CRK25244.1 - 0.18 11.6 0.1 0.3 10.9 0.1 1.2 1 0 0 1 1 1 0 Phage-related minor tail protein Arrestin_N PF00339.29 CRK25245.1 - 3.9e-16 59.4 0.0 9.1e-16 58.2 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 CRK25245.1 - 1.5e-05 25.5 0.0 0.0057 17.1 0.0 2.7 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain CYSTM PF12734.7 CRK25246.1 - 4.6e-05 23.6 40.7 4.6e-05 23.6 40.7 5.1 1 1 3 4 4 4 1 Cysteine-rich TM module stress tolerance SH3_9 PF14604.6 CRK25247.1 - 1.5e-28 98.4 3.7 2e-13 50.0 0.2 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 CRK25247.1 - 3.5e-27 93.8 4.8 2.4e-14 52.6 0.3 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 CRK25247.1 - 4.6e-17 61.4 0.2 2.8e-08 33.3 0.0 2.9 3 0 0 3 3 3 2 Variant SH3 domain Cofilin_ADF PF00241.20 CRK25247.1 - 1.3e-15 57.2 0.0 2.6e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DEC-1_N PF04625.13 CRK25247.1 - 0.03 13.3 8.5 0.014 14.5 2.2 2.4 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region DGF-1_C PF11040.8 CRK25247.1 - 5.5 7.1 6.5 5.4 7.1 0.6 2.9 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus GCIP PF13324.6 CRK25257.1 - 0.026 14.1 0.5 0.026 14.1 0.5 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Cwf_Cwc_15 PF04889.12 CRK25257.1 - 0.2 11.4 4.4 0.25 11.0 4.4 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Pyr_redox_2 PF07992.14 CRK25271.1 - 3.6e-06 26.4 0.0 4.3e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CRK25271.1 - 6.2e-06 26.4 0.0 1.2e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Med9 PF07544.13 CRK25274.1 - 6.3e-13 48.6 3.7 7.1e-13 48.5 3.7 1.0 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Phage_GP20 PF06810.11 CRK25274.1 - 0.00025 20.9 1.3 0.00025 20.9 1.3 1.0 1 0 0 1 1 1 1 Phage minor structural protein GP20 NPV_P10 PF05531.12 CRK25274.1 - 0.0046 17.4 0.6 0.0052 17.2 0.6 1.0 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein Pil1 PF13805.6 CRK25274.1 - 0.0048 16.4 2.5 0.0048 16.4 2.5 1.0 1 0 0 1 1 1 1 Eisosome component PIL1 Spectrin PF00435.21 CRK25274.1 - 0.007 16.8 1.8 0.0071 16.8 1.8 1.1 1 0 0 1 1 1 1 Spectrin repeat Bcr-Abl_Oligo PF09036.10 CRK25274.1 - 0.042 13.8 1.4 0.063 13.3 1.1 1.4 1 1 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain DUF5339 PF17274.2 CRK25274.1 - 0.049 14.5 0.6 0.074 13.9 0.5 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5339) XhlA PF10779.9 CRK25274.1 - 0.057 13.6 2.7 0.1 12.8 2.1 1.6 1 1 1 2 2 2 0 Haemolysin XhlA Lipoprotein_20 PF13942.6 CRK25274.1 - 0.082 12.8 3.4 0.083 12.8 3.4 1.1 1 0 0 1 1 1 0 YfhG lipoprotein Profilin PF00235.19 CRK25275.1 - 1.4e-20 73.9 0.1 1.5e-20 73.8 0.1 1.0 1 0 0 1 1 1 1 Profilin Fcf1 PF04900.12 CRK25276.1 - 2.7e-27 95.1 0.1 5.5e-27 94.1 0.1 1.6 1 0 0 1 1 1 1 Fcf1 PP2C_2 PF13672.6 CRK25276.1 - 0.0018 18.0 0.0 0.003 17.2 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 CRK25276.1 - 0.0063 16.4 0.0 0.023 14.6 0.0 1.9 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 CRK25276.1 - 0.021 14.5 0.0 1.1 8.9 0.0 2.3 2 0 0 2 2 2 0 Protein phosphatase 2C CDC45 PF02724.14 CRK25276.1 - 1.1 7.5 9.0 1.5 7.0 9.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Pkinase PF00069.25 CRK25278.1 - 8.7e-54 182.6 0.0 2.2e-53 181.3 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK25278.1 - 2.5e-23 82.7 0.0 4.6e-23 81.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 CRK25278.1 - 7.5e-10 39.0 0.2 1e-08 35.4 0.2 2.4 2 0 0 2 2 2 1 FHA domain Kdo PF06293.14 CRK25278.1 - 0.0032 16.8 0.0 0.0059 16.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Yop-YscD_cpl PF16697.5 CRK25278.1 - 0.011 16.1 0.1 0.039 14.3 0.0 2.0 2 0 0 2 2 2 0 Inner membrane component of T3SS, cytoplasmic domain FTA2 PF13095.6 CRK25278.1 - 0.17 11.5 0.0 7.9 6.0 0.0 2.4 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 ABC_membrane_3 PF13748.6 CRK25278.1 - 0.31 10.3 0.5 0.5 9.6 0.5 1.2 1 0 0 1 1 1 0 ABC transporter transmembrane region F-box PF00646.33 CRK25279.1 - 3e-05 23.8 0.4 8e-05 22.4 0.4 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 CRK25279.1 - 6.8e-05 22.7 1.0 0.00022 21.0 1.0 1.9 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 CRK25279.1 - 0.0041 17.0 0.2 0.011 15.6 0.2 1.7 1 0 0 1 1 1 1 F-box GspL_C PF12693.7 CRK25280.1 - 0.024 14.5 2.6 0.88 9.4 0.5 2.2 2 0 0 2 2 2 0 GspL periplasmic domain DUF3433 PF11915.8 CRK25281.1 - 2e-30 105.1 16.5 1.3e-18 67.2 1.6 3.5 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) Trypan_PARP PF05887.11 CRK25281.1 - 0.077 13.0 7.9 0.25 11.3 7.9 1.8 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TonB_N PF16031.5 CRK25281.1 - 0.18 12.3 13.9 0.64 10.5 13.9 1.9 1 0 0 1 1 1 0 TonB polyproline region DUF4381 PF14316.6 CRK25281.1 - 0.61 10.3 7.6 2.5 8.3 0.5 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) Dabb PF07876.12 CRK25282.1 - 7.4e-13 48.9 0.0 8.5e-13 48.8 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Spore-coat_CotZ PF10612.9 CRK25282.1 - 0.0096 16.1 0.0 0.011 15.9 0.0 1.1 1 0 0 1 1 1 1 Spore coat protein Z Cu_amine_oxid PF01179.20 CRK25283.1 - 8.1e-165 548.7 0.0 1.1e-164 548.3 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 CRK25283.1 - 2.5e-08 34.2 0.0 7.1e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 CRK25283.1 - 8.5e-08 32.3 0.1 2e-07 31.2 0.1 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain AA_permease_2 PF13520.6 CRK25284.1 - 4e-56 190.7 41.7 4.3e-56 190.6 41.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CRK25284.1 - 1.1e-23 83.6 37.3 1.3e-23 83.3 37.3 1.0 1 0 0 1 1 1 1 Amino acid permease HgmA PF04209.13 CRK25285.1 - 8.9e-193 640.7 0.0 1e-192 640.5 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase FAA_hydrolase PF01557.18 CRK25286.1 - 3.1e-55 187.2 0.0 4.1e-55 186.8 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 CRK25286.1 - 3.1e-32 110.9 0.0 5.1e-32 110.3 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal Dabb PF07876.12 CRK25287.1 - 5.1e-13 49.5 0.0 5.7e-13 49.3 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Tudor_FRX1 PF18336.1 CRK25287.1 - 0.0018 18.1 0.1 0.0038 17.1 0.0 1.6 2 0 0 2 2 2 1 Fragile X mental retardation Tudor domain Fungal_trans PF04082.18 CRK25288.1 - 2e-15 56.6 0.1 3.7e-15 55.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK25288.1 - 8e-06 25.9 9.5 1.3e-05 25.2 9.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyl-CoA_dh_1 PF00441.24 CRK25289.1 - 2.4e-36 125.2 0.1 3.5e-36 124.7 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 CRK25289.1 - 9e-19 67.5 0.1 1.6e-18 66.7 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 CRK25289.1 - 9.1e-13 48.9 0.0 1.8e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 CRK25289.1 - 3e-09 37.3 0.0 5.4e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain p450 PF00067.22 CRK25290.1 - 8.9e-71 239.0 0.0 1.2e-70 238.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 CRK25291.1 - 5.7e-29 101.2 34.4 8.9e-29 100.5 34.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2456 PF10445.9 CRK25291.1 - 0.11 12.6 8.5 0.033 14.3 3.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2456) Epimerase PF01370.21 CRK25292.1 - 0.0004 19.9 0.0 0.0013 18.3 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 CRK25292.1 - 0.0061 15.8 0.0 2.4 7.2 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 CRK25292.1 - 0.0066 16.4 0.0 0.015 15.2 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding AMP-binding PF00501.28 CRK25293.1 - 3.4e-74 250.0 0.3 1.3e-56 192.0 0.0 2.1 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 CRK25293.1 - 3.4e-12 47.2 0.1 7.3e-12 46.1 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Fungal_trans PF04082.18 CRK25294.1 - 3.5e-19 68.9 0.4 6.2e-19 68.1 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_6 PF12697.7 CRK25294.1 - 1.1e-16 62.1 0.6 5.2e-16 59.9 0.1 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Zn_clus PF00172.18 CRK25294.1 - 2.6e-07 30.7 9.7 4.7e-07 29.8 9.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_1 PF00561.20 CRK25294.1 - 0.00019 21.2 0.0 0.00042 20.0 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CRK25294.1 - 0.00027 20.3 0.1 0.0016 17.7 0.1 2.2 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Aldedh PF00171.22 CRK25295.1 - 6.6e-150 499.6 0.0 7.4e-150 499.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 CRK25295.1 - 0.0091 15.5 0.0 3.2 7.1 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) DUF2188 PF09954.9 CRK25295.1 - 0.031 14.4 0.0 0.082 13.1 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2188) Iso_dh PF00180.20 CRK25296.1 - 1.9e-36 126.0 0.6 2e-36 125.9 0.6 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase ParE_toxin PF05016.15 CRK25300.1 - 0.12 13.0 0.0 0.14 12.8 0.0 1.1 1 0 0 1 1 1 0 ParE toxin of type II toxin-antitoxin system, parDE Tim54 PF11711.8 CRK25326.1 - 4.9e-76 256.0 0.1 5.4e-76 255.8 0.1 1.0 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 NMT_C PF02799.15 CRK25355.1 - 1.1e-44 152.5 0.8 1.2e-44 152.4 0.8 1.0 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain DNase-RNase PF02577.14 CRK25355.1 - 0.14 11.8 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 Bifunctional nuclease Glyco_hydro_61 PF03443.14 CRK25376.1 - 5e-38 131.1 0.0 6.1e-38 130.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Peptidase_C53 PF05550.11 CRK25376.1 - 0.068 12.9 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Pestivirus Npro endopeptidase C53 SRAP PF02586.14 CRK25378.1 - 4.9e-82 274.7 0.3 1.9e-81 272.8 0.0 1.8 2 0 0 2 2 2 1 SOS response associated peptidase (SRAP) ABC_membrane PF00664.23 CRK25380.1 - 1.3e-33 116.8 5.5 1.3e-33 116.8 5.5 1.7 2 0 0 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.27 CRK25380.1 - 1.3e-32 113.2 0.0 8.6e-32 110.5 0.0 2.2 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 CRK25380.1 - 1.2e-05 24.9 0.1 0.00022 20.7 0.0 2.6 1 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 CRK25380.1 - 0.017 15.0 0.0 0.041 13.8 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase SbcCD_C PF13558.6 CRK25380.1 - 0.086 13.1 0.2 1.5 9.1 0.2 2.6 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 CRK25380.1 - 0.11 12.2 0.1 0.34 10.7 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain TRAM1 PF08390.11 CRK25382.1 - 3.1e-23 81.2 0.0 5.4e-23 80.4 0.0 1.4 1 0 0 1 1 1 1 TRAM1-like protein TRAM_LAG1_CLN8 PF03798.16 CRK25382.1 - 1.5 8.5 7.5 0.8 9.4 4.8 1.8 2 1 0 2 2 2 0 TLC domain ANAPC_CDC26 PF10471.9 CRK25384.1 - 0.029 15.2 4.4 0.029 15.2 4.4 3.6 4 0 0 4 4 4 0 Anaphase-promoting complex APC subunit CDC26 Spt20 PF12090.8 CRK25384.1 - 0.051 13.2 3.1 0.11 12.1 3.1 1.5 1 0 0 1 1 1 0 Spt20 family MAP65_ASE1 PF03999.12 CRK25384.1 - 8.3 5.0 7.9 12 4.5 7.9 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) TRAM1 PF08390.11 CRK25387.1 - 9e-24 82.9 0.0 9e-24 82.9 0.0 2.2 2 0 0 2 2 2 1 TRAM1-like protein TRAM_LAG1_CLN8 PF03798.16 CRK25387.1 - 4.2e-22 78.8 15.3 8.3e-22 77.9 15.3 1.5 1 0 0 1 1 1 1 TLC domain KTI12 PF08433.10 CRK25390.1 - 2.9e-58 197.5 0.0 6.2e-58 196.4 0.0 1.6 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Zn_clus PF00172.18 CRK25390.1 - 0.05 13.7 12.1 0.11 12.6 12.1 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain RTA1 PF04479.13 CRK25394.1 - 4.7e-46 157.0 6.7 4.7e-46 157.0 6.7 1.7 2 0 0 2 2 2 1 RTA1 like protein KleE PF17394.2 CRK25394.1 - 0.051 13.8 0.3 0.14 12.4 0.3 1.7 1 0 0 1 1 1 0 Uncharacterized KleE stable inheritance protein Zn_clus PF00172.18 CRK25396.1 - 6.7e-09 35.7 7.6 1.1e-08 35.0 7.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 CRK25398.1 - 0.008 16.6 4.0 0.21 12.1 0.1 3.1 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CRK25398.1 - 0.017 15.9 3.5 8.8 7.5 1.2 3.2 2 0 0 2 2 2 0 C2H2-type zinc finger DUF753 PF05444.12 CRK25398.1 - 0.06 13.3 3.7 0.098 12.6 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF753) DUF1749 PF08538.10 CRK25400.1 - 3.3e-79 266.1 0.0 5.6e-79 265.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Hydrolase_4 PF12146.8 CRK25400.1 - 1.5e-07 31.0 0.0 2.3e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CRK25400.1 - 1.3e-05 25.0 0.0 2.7e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CRK25400.1 - 0.011 15.2 0.1 1.1 8.7 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family BAAT_C PF08840.11 CRK25400.1 - 0.21 11.5 0.0 3.2 7.6 0.0 2.3 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal UME PF08064.13 CRK25402.1 - 0.079 12.9 0.1 2.1 8.3 0.0 3.1 2 1 1 3 3 3 0 UME (NUC010) domain Cnd1 PF12717.7 CRK25402.1 - 0.15 12.1 1.9 0.26 11.3 0.8 2.0 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Asparaginase_C PF17763.1 CRK25402.1 - 1.1 9.5 4.1 6.1 7.1 4.1 2.2 1 1 0 1 1 1 0 Glutaminase/Asparaginase C-terminal domain Pkinase PF00069.25 CRK25404.1 - 1.2e-32 113.4 0.0 2e-32 112.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK25404.1 - 2.7e-21 76.0 0.0 4.2e-21 75.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CRK25404.1 - 0.0052 16.1 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like ApoLp-III PF07464.11 CRK25404.1 - 0.007 16.5 2.5 3.1 7.9 0.2 2.5 2 0 0 2 2 2 2 Apolipophorin-III precursor (apoLp-III) MtrG PF04210.13 CRK25404.1 - 0.011 15.6 0.8 6.7 6.6 0.1 2.5 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G DUF1687 PF07955.11 CRK25404.1 - 0.031 14.7 0.1 10 6.6 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1687) DUF5476 PF17570.2 CRK25404.1 - 0.27 11.7 6.2 4.1 7.9 0.7 3.7 2 0 0 2 2 2 0 Family of unknown function (DUF5476) Pkinase_fungal PF17667.1 CRK25404.1 - 4.8 5.8 4.5 1.8 7.3 0.0 2.4 3 0 0 3 3 3 0 Fungal protein kinase RTP1_C1 PF10363.9 CRK25405.1 - 3.4e-05 24.0 0.0 0.089 13.0 0.0 3.3 3 0 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 LcrV PF04792.12 CRK25405.1 - 0.086 12.1 0.8 8.5 5.6 0.1 2.3 2 0 0 2 2 2 0 V antigen (LcrV) protein ANAPC_CDC26 PF10471.9 CRK25405.1 - 3.8 8.4 7.6 0.74 10.7 0.2 2.8 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 WD40 PF00400.32 CRK25407.1 - 1.4e-11 44.8 0.0 0.13 13.2 0.0 6.0 7 0 0 7 7 7 4 WD domain, G-beta repeat Nucleoporin_N PF08801.11 CRK25407.1 - 0.022 13.5 0.0 1.8 7.2 0.0 2.8 2 1 1 3 3 3 0 Nup133 N terminal like ANAPC4_WD40 PF12894.7 CRK25407.1 - 0.028 14.7 0.0 7.2 7.0 0.0 3.4 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CRK25407.1 - 0.04 12.6 0.0 4.6 5.8 0.0 2.1 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Lgl_C PF08596.10 CRK25407.1 - 0.054 12.2 0.0 0.08 11.6 0.0 1.1 1 0 0 1 1 1 0 Lethal giant larvae(Lgl) like, C-terminal BBS2_Mid PF14783.6 CRK25407.1 - 0.12 12.4 0.0 14 5.8 0.0 3.4 4 0 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region INSIG PF07281.12 CRK25408.1 - 3.5e-119 396.1 0.7 3.7e-85 284.9 0.6 2.1 1 1 1 2 2 2 2 Insulin-induced protein (INSIG) DUF2905 PF11146.8 CRK25408.1 - 0.13 12.5 5.8 14 5.9 0.1 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2905) LON_substr_bdg PF02190.16 CRK25410.1 - 3.2e-26 92.5 0.0 4.3e-26 92.1 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 CRK25410.1 - 1.5e-13 50.3 17.9 3.7e-11 42.7 9.8 2.8 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CRK25410.1 - 2.1e-10 40.4 23.1 1.2e-08 34.8 5.4 3.2 2 1 1 3 3 3 2 RING-type zinc-finger zf-C3HC4_4 PF15227.6 CRK25410.1 - 2.3e-10 40.5 22.8 2e-05 24.6 11.2 2.6 2 0 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 CRK25410.1 - 4e-09 36.2 15.6 2.7e-07 30.3 6.8 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CRK25410.1 - 7.2e-09 35.4 17.1 2.7e-06 27.2 8.9 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CRK25410.1 - 3.7e-08 33.2 20.6 6.2e-06 26.1 8.8 2.5 2 0 0 2 2 2 2 zinc-RING finger domain zf-RING_2 PF13639.6 CRK25410.1 - 4e-08 33.5 22.6 5.4e-07 29.8 9.7 2.8 2 0 0 2 2 2 2 Ring finger domain Prok-RING_4 PF14447.6 CRK25410.1 - 2.5e-05 24.0 18.2 0.00015 21.6 7.6 2.6 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 CRK25410.1 - 0.00042 20.0 6.3 0.00065 19.4 2.2 2.7 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 CRK25410.1 - 0.0085 16.4 4.6 0.0085 16.4 4.6 2.4 3 0 0 3 3 3 1 RING-H2 zinc finger domain U-box PF04564.15 CRK25410.1 - 0.033 14.3 0.0 0.47 10.7 0.0 2.4 2 0 0 2 2 2 0 U-box domain zf-RING_10 PF16685.5 CRK25410.1 - 0.086 13.0 17.1 0.032 14.3 6.6 2.4 2 0 0 2 2 2 0 zinc RING finger of MSL2 DZR PF12773.7 CRK25410.1 - 8 6.6 13.0 0.41 10.7 0.6 3.0 3 1 1 4 4 3 0 Double zinc ribbon efThoc1 PF11957.8 CRK25412.1 - 1.5e-141 472.5 0.2 2.2e-141 471.9 0.2 1.2 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Guanylate_kin PF00625.21 CRK25412.1 - 1.2e-33 116.3 0.0 2.7e-33 115.2 0.0 1.6 1 0 0 1 1 1 1 Guanylate kinase MMR_HSR1 PF01926.23 CRK25412.1 - 0.0011 19.0 0.0 0.0026 17.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 CRK25412.1 - 0.0085 16.5 0.0 0.041 14.3 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 CRK25412.1 - 0.07 13.7 0.2 0.32 11.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 CRK25412.1 - 0.083 13.2 0.0 0.43 10.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain Aquarius_N PF16399.5 CRK25415.1 - 0 1065.0 0.0 0 1064.6 0.0 1.1 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_12 PF13087.6 CRK25415.1 - 7.2e-27 94.3 0.0 1.1e-26 93.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CRK25415.1 - 3.5e-21 76.2 0.0 1.1e-20 74.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CRK25415.1 - 2.3e-07 30.7 0.0 0.00076 19.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain ResIII PF04851.15 CRK25415.1 - 1.7e-05 24.9 0.0 3.9e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 CRK25415.1 - 1.8e-05 25.1 0.0 4.2e-05 23.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CRK25415.1 - 0.0019 18.6 0.2 0.013 15.9 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain Viral_helicase1 PF01443.18 CRK25415.1 - 0.0023 17.7 0.4 0.12 12.1 0.0 3.0 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA PF00004.29 CRK25415.1 - 0.004 17.6 0.0 0.0094 16.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.15 CRK25415.1 - 0.0053 16.1 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain DUF2075 PF09848.9 CRK25415.1 - 0.017 14.3 0.5 0.034 13.4 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 CRK25415.1 - 0.025 14.8 0.0 0.14 12.4 0.0 2.3 1 1 1 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 CRK25415.1 - 0.048 12.7 0.0 0.077 12.1 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 CRK25415.1 - 0.057 13.7 0.0 2.1 8.6 0.0 2.9 3 0 0 3 3 3 0 AAA domain SMC_N PF02463.19 CRK25415.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 CRK25415.1 - 0.12 11.6 0.0 0.27 10.5 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin DEAD PF00270.29 CRK25415.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase UvrD_C_2 PF13538.6 CRK25415.1 - 0.17 11.7 1.0 0.76 9.7 0.2 2.3 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain eIF_4G1 PF12152.8 CRK25417.1 - 0.016 15.4 0.0 0.048 13.9 0.0 1.9 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4G1 MIF4G PF02854.19 CRK25419.1 - 3e-53 180.6 0.0 3.8e-53 180.3 0.0 1.1 1 0 0 1 1 1 1 MIF4G domain DNA_pol_B PF00136.21 CRK25420.1 - 1.6e-73 248.0 0.0 2e-73 247.7 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 CRK25420.1 - 1.1e-68 230.7 0.1 1.6e-68 230.1 0.1 1.3 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger MIF4G PF02854.19 CRK25421.1 - 4.5e-54 183.3 0.1 5.6e-54 183.0 0.1 1.1 1 0 0 1 1 1 1 MIF4G domain Eno-Rase_FAD_bd PF07055.12 CRK25421.1 - 0.19 12.2 0.0 0.6 10.6 0.0 1.8 1 0 0 1 1 1 0 Enoyl reductase FAD binding domain zf-DNA_Pol PF08996.10 CRK25423.1 - 5.3e-68 228.4 0.1 8.3e-68 227.8 0.1 1.3 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B PF00136.21 CRK25423.1 - 1.2e-66 225.3 0.0 2.4e-30 105.7 0.0 3.2 2 1 1 3 3 3 3 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 CRK25423.1 - 8.5e-47 159.9 0.0 5e-40 137.7 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 CRK25423.1 - 4.9e-24 84.2 9.7 4.9e-24 84.2 9.7 2.5 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_2 PF03175.13 CRK25423.1 - 2.2e-05 23.5 0.0 0.19 10.5 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase type B, organellar and viral DUF1651 PF07864.11 CRK25423.1 - 0.19 12.1 0.2 54 4.2 0.0 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1651) PPR_2 PF13041.6 CRK25425.1 - 9e-26 89.8 0.0 1.9e-15 56.8 0.0 3.0 2 1 1 3 3 3 2 PPR repeat family PPR_3 PF13812.6 CRK25425.1 - 1.9e-10 40.7 0.0 4.7e-05 23.4 0.0 2.7 2 0 0 2 2 2 2 Pentatricopeptide repeat domain PPR PF01535.20 CRK25425.1 - 5e-08 32.7 0.1 0.012 15.9 0.0 4.2 3 1 1 4 4 4 2 PPR repeat PPR_long PF17177.4 CRK25425.1 - 6.3e-07 29.0 0.1 9.4e-05 21.9 0.1 2.3 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 CRK25425.1 - 2.3e-06 27.2 0.0 0.88 9.3 0.0 3.9 3 0 0 3 3 3 3 PPR repeat SRP_TPR_like PF17004.5 CRK25425.1 - 0.033 14.2 0.1 0.065 13.3 0.1 1.4 1 0 0 1 1 1 0 Putative TPR-like repeat DUF1539 PF07560.11 CRK25425.1 - 0.07 13.2 1.7 0.17 12.0 0.1 2.4 3 1 0 3 3 3 0 Domain of Unknown Function (DUF1539) DNA_pol_alpha_N PF12254.8 CRK25427.1 - 1.3e-24 86.0 11.9 2e-24 85.4 9.7 2.6 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_exo1 PF03104.19 CRK25427.1 - 8.7e-18 64.5 0.0 1.3e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain PPR_2 PF13041.6 CRK25429.1 - 9.4e-28 96.2 0.0 2.6e-17 62.7 0.0 3.0 2 1 1 3 3 3 2 PPR repeat family PPR_3 PF13812.6 CRK25429.1 - 1.9e-12 47.0 0.0 3.7e-05 23.7 0.0 2.8 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR PF01535.20 CRK25429.1 - 2.4e-09 36.8 0.4 0.0092 16.2 0.0 4.7 4 1 0 4 4 4 2 PPR repeat PPR_1 PF12854.7 CRK25429.1 - 2.8e-08 33.3 0.0 0.71 9.6 0.0 4.7 4 0 0 4 4 4 3 PPR repeat PPR_long PF17177.4 CRK25429.1 - 5.3e-08 32.5 0.2 2.8e-07 30.1 0.2 2.0 1 1 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP ATP13 PF12921.7 CRK25429.1 - 0.00039 20.3 0.0 0.71 9.7 0.0 3.7 2 1 2 4 4 4 1 Mitochondrial ATPase expression DUF1539 PF07560.11 CRK25429.1 - 0.031 14.4 1.6 0.076 13.1 0.1 2.4 3 1 0 3 3 3 0 Domain of Unknown Function (DUF1539) SRP_TPR_like PF17004.5 CRK25429.1 - 0.042 13.9 0.2 0.083 12.9 0.2 1.4 1 0 0 1 1 1 0 Putative TPR-like repeat Btz PF09405.10 CRK25431.1 - 0.00097 19.4 0.2 0.0015 18.8 0.2 1.4 1 1 0 1 1 1 1 CASC3/Barentsz eIF4AIII binding CTP_synth_N PF06418.14 CRK25433.1 - 4.3e-125 416.4 0.1 7.1e-125 415.6 0.1 1.3 1 0 0 1 1 1 1 CTP synthase N-terminus RRM_1 PF00076.22 CRK25433.1 - 3.4e-59 196.6 0.0 1.4e-20 72.9 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GATase PF00117.28 CRK25433.1 - 3.8e-56 189.9 0.0 8.5e-56 188.7 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase class-I RRM_occluded PF16842.5 CRK25433.1 - 1.9e-08 34.1 0.0 0.013 15.4 0.0 3.5 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_5 PF13893.6 CRK25433.1 - 2.1e-08 33.8 0.0 4.4e-05 23.1 0.0 3.1 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CRK25433.1 - 4.9e-06 26.4 0.1 0.75 9.8 0.0 3.6 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Peptidase_C26 PF07722.13 CRK25433.1 - 9.9e-06 25.5 0.0 2.7e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 Peptidase C26 Cas_Cas2CT1978 PF09707.10 CRK25433.1 - 0.0018 18.3 0.0 1.6 8.9 0.0 2.6 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) RRM_7 PF16367.5 CRK25433.1 - 0.016 15.3 0.1 4.2 7.5 0.0 3.2 3 0 0 3 3 3 0 RNA recognition motif CbiA PF01656.23 CRK25433.1 - 0.051 13.6 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain PH PF00169.29 CRK25435.1 - 2.6e-25 89.0 1.3 2e-13 50.8 0.3 2.2 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 CRK25435.1 - 4.2e-11 43.2 4.4 0.00022 21.6 0.6 3.2 2 1 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.6 CRK25435.1 - 9.9e-11 42.1 4.5 8e-07 29.4 1.5 3.6 2 2 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.6 CRK25435.1 - 4e-05 23.8 0.2 9.2e-05 22.7 0.2 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain CTU2 PF10288.9 CRK25436.1 - 8.2e-10 38.9 0.1 8.2e-08 32.5 0.1 2.4 1 1 0 1 1 1 1 Cytoplasmic tRNA 2-thiolation protein 2 Crust_neurohorm PF01147.17 CRK25436.1 - 0.062 13.1 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family Mito_carr PF00153.27 CRK25437.1 - 2.9e-32 110.5 0.9 4.3e-15 55.4 0.8 2.4 2 1 0 2 2 2 2 Mitochondrial carrier protein SRP9-21 PF05486.12 CRK25438.1 - 5.5e-33 113.2 0.2 1.8e-32 111.6 0.0 2.0 2 0 0 2 2 2 1 Signal recognition particle 9 kDa protein (SRP9) WD40 PF00400.32 CRK25438.1 - 1.3e-12 48.0 6.0 4.5e-07 30.5 0.1 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK25438.1 - 0.00022 21.4 0.0 0.85 10.0 0.0 4.1 4 1 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Ribonuc_red_sm PF00268.21 CRK25439.1 - 3.8e-122 407.1 1.8 4.6e-122 406.8 1.8 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Mrr_cat PF04471.12 CRK25439.1 - 0.055 13.5 0.1 0.13 12.3 0.0 1.6 2 0 0 2 2 2 0 Restriction endonuclease DCP2 PF05026.13 CRK25440.1 - 9.9e-31 105.9 0.5 2.2e-30 104.8 0.5 1.6 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 CRK25440.1 - 6.1e-15 55.4 0.0 1.3e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain Rubredoxin PF00301.20 CRK25440.1 - 0.054 13.5 0.2 0.17 12.0 0.2 1.9 1 0 0 1 1 1 0 Rubredoxin Lung_7-TM_R PF06814.13 CRK25441.1 - 2.8e-69 233.6 19.6 3.5e-69 233.3 19.6 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor Pkinase PF00069.25 CRK25441.1 - 1.1e-26 93.8 0.0 1.8e-26 93.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK25441.1 - 0.00044 19.6 0.0 0.00087 18.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase SurA_N_3 PF13624.6 CRK25441.1 - 0.2 11.4 0.6 13 5.6 0.2 2.7 2 0 0 2 2 2 0 SurA N-terminal domain DUF1980 PF09323.10 CRK25441.1 - 4.4 7.2 7.1 0.4 10.6 0.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1980) Pro_isomerase PF00160.21 CRK25442.1 - 6.6e-51 172.7 0.1 1.1e-50 172.0 0.1 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U-box PF04564.15 CRK25442.1 - 0.00018 21.6 0.0 0.00073 19.7 0.0 2.0 2 0 0 2 2 2 1 U-box domain zf-NOSIP PF15906.5 CRK25442.1 - 0.011 15.8 0.0 0.028 14.5 0.0 1.7 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein DUF3541 PF12060.8 CRK25443.1 - 0.089 12.5 0.4 0.16 11.6 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3541) RasGEF PF00617.19 CRK25444.1 - 2.9e-59 200.2 0.0 6.2e-59 199.2 0.0 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 CRK25444.1 - 1.6e-44 150.4 0.5 1.2e-27 96.1 0.1 2.6 2 0 0 2 2 2 2 RasGEF N-terminal motif Cep57_CLD PF14073.6 CRK25444.1 - 0.0038 17.3 10.8 0.21 11.6 1.4 2.8 3 0 0 3 3 3 2 Centrosome localisation domain of Cep57 Acetyltransf_18 PF18014.1 CRK25444.1 - 0.082 12.7 0.0 20 5.0 0.0 2.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain SCA7 PF08313.12 CRK25446.1 - 2.6e-31 107.3 0.1 8.4e-31 105.7 0.1 1.9 1 0 0 1 1 1 1 SCA7, zinc-binding domain VWA_3_C PF18571.1 CRK25446.1 - 0.022 14.6 0.0 0.049 13.5 0.0 1.6 1 0 0 1 1 1 0 von Willebrand factor type A C-terminal domain CDC45 PF02724.14 CRK25446.1 - 0.08 11.2 9.2 0.092 11.0 9.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Zn_clus PF00172.18 CRK25447.1 - 1.4e-08 34.7 11.7 2.2e-08 34.1 11.7 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 CRK25447.1 - 0.0002 20.3 0.0 0.00036 19.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ribosomal_S9 PF00380.19 CRK25448.1 - 0.092 13.3 5.5 0.13 12.8 5.2 1.6 1 1 0 1 1 1 0 Ribosomal protein S9/S16 Acyltransferase PF01553.21 CRK25449.1 - 9.5e-06 25.3 0.0 1.9e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Acyltransferase PF01553.21 CRK25450.1 - 0.0003 20.4 0.0 0.00035 20.2 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Pkinase PF00069.25 CRK25451.1 - 5.3e-77 258.7 0.0 6.3e-77 258.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK25451.1 - 1.2e-37 129.6 0.0 1.7e-37 129.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CRK25451.1 - 0.00072 18.6 0.0 0.011 14.7 0.0 2.1 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CRK25451.1 - 0.023 14.0 0.1 0.046 13.1 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CRK25451.1 - 0.023 14.6 0.0 0.061 13.2 0.0 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 CRK25451.1 - 0.048 13.0 0.1 0.16 11.2 0.0 1.8 1 1 0 2 2 2 0 Kinase-like PAP_central PF04928.17 CRK25452.1 - 1.1e-110 368.4 0.0 1.5e-110 368.0 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 CRK25452.1 - 1.7e-66 223.1 0.7 2.7e-66 222.4 0.0 1.7 2 0 0 2 2 2 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 CRK25452.1 - 6e-10 39.3 0.1 1.2e-09 38.3 0.1 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain MMR_HSR1 PF01926.23 CRK25452.1 - 0.0077 16.3 0.0 0.016 15.3 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Peptidase_S49 PF01343.18 CRK25452.1 - 0.014 15.3 0.1 0.029 14.3 0.1 1.4 1 0 0 1 1 1 0 Peptidase family S49 DUF815 PF05673.13 CRK25452.1 - 0.037 13.2 0.0 0.082 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RsgA_GTPase PF03193.16 CRK25452.1 - 0.053 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 CRK25452.1 - 0.076 13.4 0.0 0.2 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 CRK25452.1 - 0.084 13.2 0.1 0.38 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 CRK25452.1 - 0.1 13.1 0.0 0.34 11.4 0.0 1.8 2 0 0 2 2 1 0 ABC transporter Roc PF08477.13 CRK25452.1 - 0.11 12.8 0.1 0.71 10.1 0.0 2.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Polbeta PF18765.1 CRK25452.1 - 0.11 12.6 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase MCM PF00493.23 CRK25452.1 - 0.19 10.8 0.0 0.36 9.9 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain Dynamin_N PF00350.23 CRK25452.1 - 2.4 8.2 4.8 7.3 6.6 0.2 3.1 1 1 1 2 2 2 0 Dynamin family Tubulin_3 PF14881.6 CRK25453.1 - 4.9e-70 234.9 0.1 8.1e-70 234.2 0.1 1.3 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.9 CRK25453.1 - 2.7e-37 127.7 0.0 5.3e-37 126.7 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.25 CRK25453.1 - 5.1e-07 30.1 0.0 0.0081 16.4 0.0 2.2 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain Forkhead PF00250.18 CRK25454.1 - 1.9e-33 114.6 0.2 3.2e-33 113.8 0.2 1.3 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 CRK25454.1 - 4.9e-11 42.8 0.1 2.1e-10 40.8 0.0 2.1 1 1 1 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 CRK25454.1 - 0.0056 17.0 0.0 0.01 16.1 0.0 1.4 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain FHA_2 PF17913.1 CRK25454.1 - 0.22 11.8 0.0 0.41 10.9 0.0 1.4 1 0 0 1 1 1 0 FHA domain CLU PF13236.6 CRK25455.1 - 1.1e-74 251.0 0.0 2.1e-74 250.1 0.0 1.5 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 CRK25455.1 - 1.2e-53 181.8 0.0 3.3e-53 180.3 0.0 1.8 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 CRK25455.1 - 1.2e-26 92.8 4.3 6.8e-10 39.1 0.1 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 CRK25455.1 - 2e-23 81.5 2.2 2.8e-07 30.2 0.0 5.3 5 1 1 6 6 6 3 Tetratricopeptide repeat CLU_N PF15044.6 CRK25455.1 - 2.2e-23 82.4 0.0 2.2e-22 79.2 0.0 2.4 2 0 0 2 2 2 1 Mitochondrial function, CLU-N-term TPR_8 PF13181.6 CRK25455.1 - 0.00031 20.7 7.6 0.025 14.8 0.1 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 CRK25455.1 - 0.0065 16.5 4.9 3.4 8.0 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat Hep_59 PF07052.11 CRK25455.1 - 1.4 9.7 6.8 0.16 12.7 0.9 2.4 2 0 0 2 2 2 0 Hepatocellular carcinoma-associated antigen 59 Ferric_reduct PF01794.19 CRK25457.1 - 1.4e-23 83.4 11.7 4.1e-23 81.8 11.7 1.9 1 0 0 1 1 1 1 Ferric reductase like transmembrane component EamA PF00892.20 CRK25458.1 - 1.1e-09 38.5 23.5 8.6e-05 22.7 3.1 2.7 2 1 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 CRK25458.1 - 2e-07 30.5 1.3 3.2e-07 29.8 1.3 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.16 CRK25458.1 - 0.00054 19.4 0.2 0.00054 19.4 0.2 2.0 2 1 0 2 2 2 1 Triose-phosphate Transporter family DUF423 PF04241.15 CRK25458.1 - 0.058 13.6 5.7 0.82 9.9 0.8 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF423) CRT-like PF08627.10 CRK25458.1 - 8.2 5.3 9.1 2.9 6.7 6.0 2.0 2 1 0 2 2 2 0 CRT-like, chloroquine-resistance transporter-like DUF2985 PF11204.8 CRK25459.1 - 8.4e-20 70.7 0.1 1.8e-19 69.7 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) zf-C2H2 PF00096.26 CRK25460.1 - 1.2e-07 31.8 10.0 0.0052 17.2 2.0 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CRK25460.1 - 0.017 15.9 7.9 0.11 13.4 1.7 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CRK25460.1 - 0.03 14.7 9.8 2.7 8.6 0.2 3.8 4 0 0 4 4 4 0 Zinc-finger double domain zf-Di19 PF05605.12 CRK25460.1 - 3 8.2 5.6 0.41 11.0 0.7 2.0 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Peptidase_C2 PF00648.21 CRK25461.1 - 8.6e-28 97.2 0.0 1.3e-27 96.6 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 CRK25461.1 - 9.9e-12 45.3 0.0 3.5e-05 24.1 0.0 3.5 3 0 0 3 3 3 3 Calpain large subunit, domain III Ribosomal_L29e PF01779.17 CRK25462.1 - 8.8e-23 80.3 8.2 1.3e-22 79.8 8.2 1.3 1 0 0 1 1 1 1 Ribosomal L29e protein family ARD PF03079.14 CRK25463.1 - 2.3e-45 154.6 0.4 2.7e-45 154.4 0.4 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 CRK25463.1 - 1e-09 38.0 0.1 2.3e-09 36.8 0.0 1.6 2 0 0 2 2 2 1 Cupin domain AraC_binding PF02311.19 CRK25463.1 - 7.9e-07 29.0 0.0 1.1e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain DER1 PF04511.15 CRK25464.1 - 9.1e-36 123.6 3.1 4.8e-35 121.2 3.1 1.8 1 1 0 1 1 1 1 Der1-like family Histone PF00125.24 CRK25465.1 - 1.9e-12 47.7 0.3 2.5e-12 47.3 0.3 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Creatinase_N_2 PF16189.5 CRK25466.1 - 1.4e-50 171.5 0.0 1.3e-49 168.4 0.0 2.5 4 0 0 4 4 4 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 CRK25466.1 - 1.1e-41 142.8 0.0 1.8e-41 142.1 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 CRK25466.1 - 2.5e-20 73.5 0.2 3.1e-18 66.7 0.0 2.7 3 0 0 3 3 3 1 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 CRK25466.1 - 1.2e-19 70.1 0.9 3.6e-19 68.6 0.4 2.1 2 0 0 2 2 2 1 C-terminal region of peptidase_M24 DUF1335 PF07056.11 CRK25466.1 - 0.034 14.3 0.0 0.074 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1335) PCI PF01399.27 CRK25466.1 - 0.061 13.8 0.0 7.8 7.1 0.0 2.8 3 0 0 3 3 3 0 PCI domain Xpo1 PF08389.12 CRK25467.1 - 1.1e-07 32.0 0.5 5.6e-07 29.7 0.0 2.6 3 0 0 3 3 3 1 Exportin 1-like protein Importin_rep PF18773.1 CRK25467.1 - 0.033 13.9 0.0 0.46 10.2 0.0 2.5 2 0 0 2 2 2 0 Importin 13 repeat tRNA-synt_1b PF00579.25 CRK25468.1 - 1.2e-24 87.2 0.0 1.7e-24 86.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Ribosomal_S10 PF00338.22 CRK25468.1 - 1.2e-24 86.4 0.0 2.1e-24 85.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e CBFD_NFYB_HMF PF00808.23 CRK25469.1 - 1.1e-19 70.5 0.4 1.7e-19 69.8 0.4 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CRK25469.1 - 8.1e-15 55.3 0.1 1.6e-14 54.4 0.1 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 CRK25469.1 - 0.039 14.3 0.0 0.075 13.4 0.0 1.5 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Pol_alpha_B_N PF08418.10 CRK25469.1 - 0.045 13.7 0.1 0.07 13.1 0.1 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Sec15 PF04091.12 CRK25470.1 - 5.5e-111 371.0 3.2 5.5e-111 371.0 3.2 1.9 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like DUF3510 PF12022.8 CRK25470.1 - 0.0024 18.3 1.9 1.3 9.4 0.0 3.4 2 1 1 3 3 3 2 Domain of unknown function (DUF3510) FdhE PF04216.12 CRK25470.1 - 0.024 14.5 1.2 0.058 13.3 1.2 1.6 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation Sec8_exocyst PF04048.14 CRK25470.1 - 0.029 14.3 7.7 0.02 14.8 1.7 3.3 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain DUF4201 PF13870.6 CRK25470.1 - 0.063 13.0 6.1 0.12 12.1 3.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) GIT_CC PF16559.5 CRK25470.1 - 9.7 6.2 7.1 21 5.1 1.5 3.4 3 1 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Pantoate_transf PF02548.15 CRK25471.1 - 2e-104 348.6 0.4 2.4e-104 348.3 0.4 1.1 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 CRK25471.1 - 3.8e-07 29.8 0.8 1.2e-06 28.1 0.8 1.8 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase APG12 PF04110.13 CRK25472.1 - 6.1e-17 61.8 0.0 8e-17 61.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 CRK25472.1 - 0.0028 17.8 0.0 0.0034 17.5 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Lyase_aromatic PF00221.19 CRK25473.1 - 1.6e-149 498.6 1.8 1.6e-149 498.6 1.8 1.8 2 0 0 2 2 2 1 Aromatic amino acid lyase Ank_2 PF12796.7 CRK25473.1 - 2.7e-52 175.3 0.0 7e-17 61.8 0.0 5.7 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CRK25473.1 - 1e-39 134.4 0.0 2.5e-09 37.5 0.0 7.0 3 1 4 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 CRK25473.1 - 6.3e-39 127.5 0.0 0.00038 20.7 0.0 9.1 8 0 0 8 8 8 7 Ankyrin repeat Ank PF00023.30 CRK25473.1 - 1.5e-31 107.4 0.0 0.0015 18.9 0.0 8.7 9 0 0 9 9 7 7 Ankyrin repeat Ank_5 PF13857.6 CRK25473.1 - 3e-31 107.0 0.0 6.3e-08 32.7 0.0 6.7 1 1 3 6 6 6 5 Ankyrin repeats (many copies) NACHT PF05729.12 CRK25473.1 - 2.9e-06 27.3 0.1 7.4e-06 26.0 0.1 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 CRK25473.1 - 0.0001 22.6 0.2 0.00041 20.6 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA PF00004.29 CRK25473.1 - 0.003 18.0 0.0 0.26 11.7 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF3220 PF11516.8 CRK25473.1 - 0.02 15.1 0.0 0.11 12.8 0.0 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3120) DUF932 PF06067.11 CRK25473.1 - 0.053 13.3 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF932) Torsin PF06309.11 CRK25473.1 - 0.11 12.6 0.0 0.35 11.0 0.0 1.8 1 0 0 1 1 1 0 Torsin DUF4106 PF13388.6 CRK25473.1 - 0.2 10.9 0.7 0.35 10.0 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4106) Dfp1_Him1_M PF08630.10 CRK25475.1 - 3e-42 143.8 0.2 9.5e-42 142.2 0.0 2.1 2 0 0 2 2 2 1 Dfp1/Him1, central region zf-DBF PF07535.12 CRK25475.1 - 1.8e-16 60.0 1.0 1.8e-16 60.0 1.0 1.7 2 0 0 2 2 2 1 DBF zinc finger PTCB-BRCT PF12738.7 CRK25475.1 - 0.0038 17.1 0.0 0.017 15.0 0.0 2.0 2 0 0 2 2 2 1 twin BRCT domain Peptidase_M24 PF00557.24 CRK25477.1 - 2.2e-51 174.5 0.0 3.2e-51 174.0 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 CRK25477.1 - 3.4e-35 120.4 0.0 5.3e-35 119.8 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain HLH PF00010.26 CRK25479.1 - 2e-15 56.5 0.0 4.7e-15 55.3 0.0 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SR-25 PF10500.9 CRK25479.1 - 0.51 9.9 10.9 2.9 7.4 7.3 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Fez1 PF06818.15 CRK25479.1 - 4.2 7.8 6.7 6.9 7.1 6.7 1.2 1 0 0 1 1 1 0 Fez1 CN_hydrolase PF00795.22 CRK25483.1 - 1e-27 97.2 0.0 1.7e-27 96.4 0.0 1.3 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase LysR_substrate PF03466.20 CRK25483.1 - 0.0008 18.8 0.6 4.2 6.7 0.1 3.2 2 1 1 3 3 3 3 LysR substrate binding domain Rap1_C PF11626.8 CRK25485.1 - 6.9e-25 87.0 0.0 4.4e-24 84.4 0.0 2.4 2 0 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.11 CRK25485.1 - 2.5e-18 66.0 0.4 7.4e-10 38.9 0.3 2.8 2 0 0 2 2 2 2 Rap1 Myb domain BRCT_2 PF16589.5 CRK25485.1 - 1.2e-09 38.4 0.0 2.5e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain ARID PF01388.21 CRK25485.1 - 1.6e-08 35.1 0.0 6.1e-08 33.2 0.0 2.0 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain Rap1-DNA-bind PF09197.10 CRK25485.1 - 0.0075 16.9 0.8 0.023 15.3 0.1 2.3 2 1 0 2 2 2 1 Rap1, DNA-binding DHHC PF01529.20 CRK25487.1 - 1.1e-30 106.5 3.8 1.1e-30 106.5 3.8 2.4 3 0 0 3 3 3 1 DHHC palmitoyltransferase Methyltransf_23 PF13489.6 CRK25493.1 - 7.8e-19 68.1 0.0 1.2e-18 67.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK25493.1 - 3.8e-10 40.3 0.0 1.8e-09 38.1 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CRK25493.1 - 5.9e-08 33.3 0.0 2.6e-07 31.2 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK25493.1 - 1.7e-07 31.9 0.0 8.8e-07 29.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK25493.1 - 1.1e-05 25.2 0.0 0.00011 22.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 CRK25493.1 - 0.00024 20.6 0.0 0.00078 18.9 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 CRK25493.1 - 0.006 16.1 0.0 0.04 13.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_2 PF00891.18 CRK25493.1 - 0.0079 15.5 0.0 0.048 12.9 0.0 2.0 2 0 0 2 2 2 1 O-methyltransferase domain Methyltransf_16 PF10294.9 CRK25493.1 - 0.0087 15.8 0.0 0.014 15.1 0.0 1.4 1 1 0 1 1 1 1 Lysine methyltransferase FtsJ PF01728.19 CRK25493.1 - 0.05 13.7 0.0 0.076 13.1 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase p450 PF00067.22 CRK25495.1 - 1.8e-55 188.5 0.0 6.3e-55 186.7 0.0 1.7 1 1 1 2 2 2 1 Cytochrome P450 Inositol_P PF00459.25 CRK25495.1 - 6.6e-49 166.8 1.1 1.5e-48 165.7 1.1 1.5 1 1 0 1 1 1 1 Inositol monophosphatase family HTH_8 PF02954.19 CRK25495.1 - 0.076 12.8 0.9 0.3 10.9 0.0 2.4 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family DUF2630 PF10944.8 CRK25495.1 - 0.27 11.7 4.2 0.084 13.3 0.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2630) Ribosomal_L6 PF00347.23 CRK25498.1 - 8.6e-18 64.8 0.0 2.3e-07 31.4 0.0 2.9 3 0 0 3 3 3 2 Ribosomal protein L6 ABC_tran PF00005.27 CRK25500.1 - 1.3e-49 168.2 0.2 4.3e-23 82.3 0.0 3.4 3 0 0 3 3 3 2 ABC transporter ABC_tran_Xtn PF12848.7 CRK25500.1 - 2.8e-21 75.3 6.2 2.8e-21 75.3 6.2 4.0 5 0 0 5 5 4 1 ABC transporter AAA_21 PF13304.6 CRK25500.1 - 8.1e-19 68.5 0.3 0.00011 22.1 0.0 4.5 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CRK25500.1 - 4.5e-10 39.3 5.8 0.0073 15.8 0.0 4.7 5 0 0 5 5 5 3 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 CRK25500.1 - 1.7e-06 28.3 0.0 0.018 15.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 CRK25500.1 - 1.7e-06 28.1 0.0 0.03 14.4 0.0 3.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.6 CRK25500.1 - 2e-06 28.4 0.0 0.13 12.8 0.0 3.4 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.6 CRK25500.1 - 4.2e-06 27.2 1.0 0.04 14.3 0.1 3.2 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 CRK25500.1 - 6.1e-06 25.9 0.1 0.071 12.9 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CRK25500.1 - 1.2e-05 25.3 1.9 0.12 12.3 0.0 3.3 2 1 1 3 3 3 2 RsgA GTPase AAA_28 PF13521.6 CRK25500.1 - 1.5e-05 25.3 0.2 0.029 14.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 CRK25500.1 - 2e-05 25.2 17.6 0.03 14.8 0.0 4.7 5 0 0 5 5 5 2 AAA domain AAA_30 PF13604.6 CRK25500.1 - 6.1e-05 22.8 4.2 0.0039 16.9 0.0 3.7 4 0 0 4 4 4 1 AAA domain AAA_33 PF13671.6 CRK25500.1 - 0.00012 22.2 0.5 0.82 9.8 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA PF00004.29 CRK25500.1 - 0.00013 22.4 0.0 1 9.8 0.1 3.1 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 CRK25500.1 - 0.00046 20.0 2.9 0.83 9.3 0.1 3.6 3 1 1 4 4 3 2 AAA domain Dynamin_N PF00350.23 CRK25500.1 - 0.00096 19.2 5.7 2.7 8.0 0.0 4.4 4 1 0 4 4 4 2 Dynamin family AAA_14 PF13173.6 CRK25500.1 - 0.0013 18.7 0.0 2.1 8.4 0.0 3.0 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 CRK25500.1 - 0.0025 17.7 0.1 1.7 8.5 0.0 2.7 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.22 CRK25500.1 - 0.0035 17.7 0.0 5.3 7.5 0.0 2.7 2 0 0 2 2 2 0 RNA helicase NTPase_1 PF03266.15 CRK25500.1 - 0.0041 17.1 0.1 0.74 9.7 0.1 2.7 2 0 0 2 2 2 1 NTPase cobW PF02492.19 CRK25500.1 - 0.0041 16.7 0.3 1.2 8.7 0.4 2.8 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_27 PF13514.6 CRK25500.1 - 0.0049 16.5 0.7 6 6.4 0.0 3.9 4 0 0 4 4 3 0 AAA domain AAA_15 PF13175.6 CRK25500.1 - 0.006 16.3 11.2 0.3 10.8 0.0 4.2 5 0 0 5 5 4 2 AAA ATPase domain Roc PF08477.13 CRK25500.1 - 0.0079 16.4 0.1 1.8 8.8 0.0 2.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 CRK25500.1 - 0.009 16.0 0.0 3.7 7.6 0.0 3.0 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 CRK25500.1 - 0.0099 15.9 0.2 3.4 7.7 0.0 2.9 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) MeaB PF03308.16 CRK25500.1 - 0.012 14.7 1.4 1.9 7.4 0.0 2.7 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_7 PF12775.7 CRK25500.1 - 0.016 14.7 0.0 8.4 5.9 0.0 2.7 3 0 0 3 3 2 0 P-loop containing dynein motor region ATP-synt_ab PF00006.25 CRK25500.1 - 0.018 14.7 0.1 0.79 9.3 0.0 2.9 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain SRP54 PF00448.22 CRK25500.1 - 0.028 14.1 0.1 5.4 6.6 0.1 2.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MobB PF03205.14 CRK25500.1 - 0.03 14.2 0.3 1.2 9.1 0.1 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.12 CRK25500.1 - 0.032 13.5 2.3 5.9 6.1 0.0 4.0 4 1 0 4 4 4 0 Zeta toxin Thymidylate_kin PF02223.17 CRK25500.1 - 0.037 13.7 0.6 1.8 8.2 0.0 3.6 3 0 0 3 3 3 0 Thymidylate kinase SbcCD_C PF13558.6 CRK25500.1 - 0.083 13.1 0.6 9.7 6.5 0.2 3.4 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF87 PF01935.17 CRK25500.1 - 0.098 12.7 7.1 0.83 9.7 0.1 3.8 4 0 0 4 4 3 0 Helicase HerA, central domain NB-ARC PF00931.22 CRK25500.1 - 0.1 11.7 0.0 17 4.5 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain Rad17 PF03215.15 CRK25500.1 - 0.14 12.1 0.1 3 7.7 0.0 2.7 3 0 0 3 3 3 0 Rad17 P-loop domain FeoB_N PF02421.18 CRK25500.1 - 0.15 11.6 0.3 6 6.4 0.0 3.2 4 0 0 4 4 3 0 Ferrous iron transport protein B AAA_19 PF13245.6 CRK25500.1 - 0.16 12.3 0.6 11 6.3 0.3 3.4 4 1 0 4 4 3 0 AAA domain AAA_17 PF13207.6 CRK25500.1 - 0.72 10.3 8.8 27 5.2 0.2 4.2 4 1 0 4 4 3 0 AAA domain Fmp27_WPPW PF10359.9 CRK25500.1 - 2 7.1 8.9 1.9 7.2 0.6 2.9 3 0 0 3 3 3 0 RNA pol II promoter Fmp27 protein domain DUF4482 PF14818.6 CRK25505.1 - 1.9 9.4 15.2 0.047 14.5 5.8 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) Pyridox_ox_2 PF12900.7 CRK25506.1 - 1.1e-14 54.6 0.0 1.8e-06 28.0 0.0 2.2 1 1 1 2 2 2 2 Pyridoxamine 5'-phosphate oxidase Spermine_synth PF01564.17 CRK25508.1 - 2e-09 37.1 0.0 3.6e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_23 PF13489.6 CRK25508.1 - 0.0015 18.4 0.0 0.0041 17.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain AlaDh_PNT_C PF01262.21 CRK25508.1 - 0.12 11.6 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain MR_MLE_C PF13378.6 CRK25510.1 - 2.1e-56 191.0 0.0 3e-56 190.4 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 CRK25510.1 - 0.012 15.8 0.1 0.036 14.3 0.0 1.8 2 0 0 2 2 2 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.11 CRK25510.1 - 0.037 13.2 0.0 0.055 12.6 0.0 1.3 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus Rad10 PF03834.14 CRK25512.1 - 4e-46 155.7 0.0 6.1e-46 155.1 0.0 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 CRK25512.1 - 0.029 15.0 0.1 0.073 13.7 0.1 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain HD-ZIP_N PF04618.12 CRK25512.1 - 0.1 13.1 2.4 0.31 11.6 2.4 1.8 1 0 0 1 1 1 0 HD-ZIP protein N terminus DNA_pol_alpha_N PF12254.8 CRK25514.1 - 0.045 13.8 0.1 0.063 13.4 0.1 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal VIT1 PF01988.19 CRK25515.1 - 5.2e-62 209.5 6.2 6.4e-62 209.2 6.2 1.1 1 0 0 1 1 1 1 VIT family Peptidase_M50B PF13398.6 CRK25515.1 - 2.8 7.5 12.1 0.34 10.5 4.2 2.3 1 1 1 2 2 2 0 Peptidase M50B-like Lactamase_B_2 PF12706.7 CRK25516.1 - 5.2e-28 97.9 0.0 2.9e-27 95.5 0.0 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 CRK25516.1 - 5e-09 36.3 0.0 8.4e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 CRK25516.1 - 0.14 12.1 5.8 0.17 11.9 3.5 2.3 2 1 0 2 2 2 0 Metallo-beta-lactamase superfamily Fungal_trans PF04082.18 CRK25517.1 - 2.4e-20 72.7 8.1 8.6e-14 51.2 0.8 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 CRK25517.1 - 1.4e-08 34.8 31.2 1.8e-05 24.9 5.8 4.4 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_3rep PF18868.1 CRK25517.1 - 0.00018 22.1 1.7 3.5 8.3 0.1 3.6 2 1 1 3 3 3 2 Zinc finger C2H2-type, 3 repeats zf-C2H2_4 PF13894.6 CRK25517.1 - 0.0023 18.6 24.9 1.2 10.1 1.4 5.4 5 0 0 5 5 5 3 C2H2-type zinc finger CUTL PF16557.5 CRK25517.1 - 0.0063 16.7 5.1 1.7 8.9 0.2 3.0 3 0 0 3 3 3 2 CUT1-like DNA-binding domain of SATB zf_C2H2_ZHX PF18387.1 CRK25517.1 - 0.0072 15.9 0.0 7.2 6.3 0.0 2.9 2 0 0 2 2 2 2 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2HE PF16278.5 CRK25517.1 - 0.034 14.6 4.9 4.6 7.8 0.1 2.7 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger HnRNPA1 PF11627.8 CRK25517.1 - 0.49 10.6 3.2 14 5.9 0.2 2.6 2 0 0 2 2 2 0 Nuclear factor hnRNPA1 zf-C2H2 PF00096.26 CRK25517.1 - 0.58 10.7 34.1 0.49 11.0 4.3 5.3 6 0 0 6 6 6 0 Zinc finger, C2H2 type LIM PF00412.22 CRK25517.1 - 1.8 8.9 5.1 25 5.2 2.1 2.6 2 0 0 2 2 2 0 LIM domain Pro_isomerase PF00160.21 CRK25518.1 - 4.1e-50 170.1 0.0 6.7e-50 169.4 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U-box PF04564.15 CRK25518.1 - 0.00021 21.4 0.0 0.00073 19.7 0.0 1.9 1 0 0 1 1 1 1 U-box domain zf-NOSIP PF15906.5 CRK25518.1 - 0.011 15.9 0.0 0.028 14.5 0.0 1.7 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein Lung_7-TM_R PF06814.13 CRK25519.1 - 1.8e-69 234.2 19.6 2.2e-69 234.0 19.6 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor SurA_N_3 PF13624.6 CRK25519.1 - 0.11 12.3 0.6 10 5.9 0.2 2.9 2 0 0 2 2 2 0 SurA N-terminal domain DUF1980 PF09323.10 CRK25519.1 - 2.1 8.2 7.0 0.29 11.0 0.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1980) DUF4492 PF14899.6 CRK25519.1 - 7.6 6.5 7.4 0.57 10.1 1.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4492) Methyltransf_28 PF02636.17 CRK25520.1 - 2.3e-81 273.3 0.0 2.9e-81 273.0 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Pkinase PF00069.25 CRK25521.1 - 5.2e-12 45.7 0.0 5.2e-12 45.7 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Lung_7-TM_R PF06814.13 CRK25521.1 - 1.7e-06 27.5 1.9 2.3e-06 27.1 1.9 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor Pkinase_Tyr PF07714.17 CRK25521.1 - 1.7e-06 27.5 0.0 2.9e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase MCM_bind PF09739.9 CRK25521.1 - 0.64 8.4 7.9 0.98 7.8 7.9 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor PTPRCAP PF15713.5 CRK25521.1 - 0.66 10.3 15.7 6.1 7.1 10.4 2.3 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated LCD1 PF09798.9 CRK25521.1 - 1 7.8 6.7 11 4.4 0.0 2.0 2 0 0 2 2 2 0 DNA damage checkpoint protein NPR3 PF03666.13 CRK25521.1 - 5.9 5.6 9.3 8 5.1 9.3 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Methyltransf_28 PF02636.17 CRK25522.1 - 1.8e-81 273.6 0.0 2.5e-81 273.2 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase BsuPI PF12690.7 CRK25522.1 - 0.028 14.4 0.1 0.055 13.5 0.1 1.4 1 0 0 1 1 1 0 Intracellular proteinase inhibitor Rubredoxin PF00301.20 CRK25522.1 - 0.031 14.3 0.2 0.084 12.9 0.2 1.8 1 0 0 1 1 1 0 Rubredoxin Pkinase PF00069.25 CRK25523.1 - 3.5e-63 213.5 0.0 5.5e-63 212.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK25523.1 - 1.8e-30 106.1 0.0 3.4e-30 105.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CRK25523.1 - 0.00015 21.2 0.0 0.00029 20.2 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CRK25523.1 - 0.0077 15.2 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CRK25523.1 - 0.032 14.2 0.0 0.032 14.2 0.0 2.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family MCM_bind PF09739.9 CRK25523.1 - 1.2 7.5 5.4 1.7 7.0 5.4 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor NPR3 PF03666.13 CRK25523.1 - 4.9 5.8 5.4 6.8 5.4 5.4 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DCP2 PF05026.13 CRK25524.1 - 5.8e-31 106.7 0.5 1.1e-30 105.8 0.5 1.5 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 CRK25524.1 - 2.8e-15 56.5 0.0 5.5e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Ribonuc_red_sm PF00268.21 CRK25525.1 - 3.8e-122 407.1 1.6 4.6e-122 406.8 1.6 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain SRP9-21 PF05486.12 CRK25526.1 - 7.1e-34 116.1 0.0 1.3e-33 115.3 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) WD40 PF00400.32 CRK25527.1 - 8e-14 51.8 6.4 2.6e-07 31.2 0.1 5.6 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK25527.1 - 0.00016 21.9 0.0 2.8 8.3 0.0 4.3 3 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Mito_carr PF00153.27 CRK25528.1 - 2.1e-53 178.2 2.4 2.1e-18 66.0 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein CTU2 PF10288.9 CRK25529.1 - 8.3e-10 38.9 0.1 8.2e-08 32.5 0.1 2.4 1 1 0 1 1 1 1 Cytoplasmic tRNA 2-thiolation protein 2 Crust_neurohorm PF01147.17 CRK25529.1 - 0.0099 15.7 0.1 0.022 14.5 0.1 1.5 1 0 0 1 1 1 1 Crustacean CHH/MIH/GIH neurohormone family PH PF00169.29 CRK25530.1 - 4.1e-25 88.3 1.0 2.8e-13 50.3 0.3 2.2 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 CRK25530.1 - 1e-10 42.0 4.6 0.00033 21.0 0.7 3.3 2 1 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.6 CRK25530.1 - 2.3e-10 40.9 4.4 1.2e-06 28.9 1.5 3.6 2 2 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.6 CRK25530.1 - 5.2e-05 23.4 0.2 0.00013 22.2 0.2 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain RRM_1 PF00076.22 CRK25532.1 - 1.6e-60 200.8 0.0 4.6e-21 74.4 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CRK25532.1 - 9.2e-10 38.3 0.0 0.0043 16.9 0.0 3.4 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_5 PF13893.6 CRK25532.1 - 1.8e-09 37.3 0.0 1.3e-05 24.8 0.0 3.0 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CRK25532.1 - 2.7e-07 30.5 0.1 0.26 11.3 0.0 3.5 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif Cas_Cas2CT1978 PF09707.10 CRK25532.1 - 0.00022 21.2 0.0 0.55 10.3 0.0 2.7 3 0 0 3 3 3 2 CRISPR-associated protein (Cas_Cas2CT1978) RRM_7 PF16367.5 CRK25532.1 - 0.0012 18.9 0.0 1.5 9.0 0.0 3.4 3 0 0 3 3 3 1 RNA recognition motif RRM_8 PF11835.8 CRK25532.1 - 0.0014 18.8 0.0 0.49 10.7 0.0 2.4 2 0 0 2 2 2 1 RRM-like domain RRM_3 PF08777.11 CRK25532.1 - 0.05 13.7 0.0 0.41 10.7 0.0 2.1 2 0 0 2 2 2 0 RNA binding motif Acetyltransf_10 PF13673.7 CRK25532.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SET_assoc PF11767.8 CRK25532.1 - 0.15 11.8 0.0 17 5.2 0.0 2.3 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated Pkinase PF00069.25 CRK25533.1 - 1.5e-50 172.0 0.1 4.8e-50 170.4 0.1 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK25533.1 - 3.3e-23 82.3 0.0 6e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CRK25533.1 - 0.00027 20.9 1.8 0.00034 20.6 0.1 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 CRK25533.1 - 0.002 17.8 0.5 0.0075 15.9 0.2 2.0 2 1 0 2 2 2 1 RIO1 family Choline_kinase PF01633.20 CRK25533.1 - 0.22 11.1 0.8 0.4 10.2 0.2 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase DNA_pol_B PF00136.21 CRK25534.1 - 1.7e-80 270.9 0.1 2.6e-80 270.4 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase family B Btz PF09405.10 CRK25534.1 - 0.015 15.5 0.1 0.04 14.2 0.1 1.7 1 0 0 1 1 1 0 CASC3/Barentsz eIF4AIII binding HTH_27 PF13463.6 CRK25534.1 - 0.056 13.9 0.1 3.3 8.3 0.0 2.8 3 0 0 3 3 3 0 Winged helix DNA-binding domain Pex24p PF06398.11 CRK25537.1 - 1.7e-36 126.0 0.0 2e-36 125.8 0.0 1.0 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF3292 PF11696.8 CRK25537.1 - 0.0069 14.8 0.7 0.012 14.0 0.3 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF3292) DUF639 PF04842.12 CRK25537.1 - 0.012 15.0 0.1 0.017 14.5 0.1 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) CDC14 PF08045.11 CRK25538.1 - 6.7e-129 429.0 0.0 8.4e-129 428.7 0.0 1.1 1 0 0 1 1 1 1 Cell division control protein 14, SIN component VSP PF03302.13 CRK25539.1 - 0.0089 14.9 3.7 0.013 14.4 3.7 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein Herpes_gE PF02480.16 CRK25539.1 - 0.067 11.9 0.0 0.097 11.4 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Rax2 PF12768.7 CRK25539.1 - 0.18 11.3 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity SKG6 PF08693.10 CRK25539.1 - 1.5 8.3 4.1 2.7 7.5 4.1 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain APH PF01636.23 CRK25540.1 - 7e-08 32.7 6.5 5e-07 29.9 6.5 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CRK25540.1 - 7.3e-08 32.0 0.0 0.00047 19.6 0.0 3.0 2 1 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 CRK25540.1 - 7e-07 28.9 0.0 2.3e-06 27.2 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_fungal PF17667.1 CRK25540.1 - 0.03 13.1 0.0 0.041 12.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pkinase_Tyr PF07714.17 CRK25540.1 - 0.032 13.5 0.0 0.043 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase RIO1 PF01163.22 CRK25540.1 - 0.076 12.6 0.0 1.1 8.8 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Ribosomal_60s PF00428.19 CRK25540.1 - 0.76 10.4 7.3 11 6.7 0.3 2.3 1 1 1 2 2 2 0 60s Acidic ribosomal protein Acyl_transf_3 PF01757.22 CRK25541.1 - 1e-43 149.8 32.1 1.3e-43 149.4 32.1 1.1 1 0 0 1 1 1 1 Acyltransferase family SUR7 PF06687.12 CRK25542.1 - 8.6e-19 68.0 11.7 1.1e-18 67.6 11.7 1.1 1 0 0 1 1 1 1 SUR7/PalI family Ribosomal_L7Ae PF01248.26 CRK25542.1 - 6e-11 41.9 0.0 9.8e-11 41.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family TMEM132D_C PF15706.5 CRK25542.1 - 1.3 8.8 5.8 2.8 7.8 0.1 2.5 1 1 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Selenoprotein_S PF06936.11 CRK25543.1 - 0.76 9.6 7.3 1.2 8.9 7.3 1.2 1 0 0 1 1 1 0 Selenoprotein S (SelS) DUF3281 PF11685.8 CRK25544.1 - 0.017 14.5 0.2 0.032 13.6 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3281) SPESP1 PF15754.5 CRK25544.1 - 0.29 10.3 1.9 0.42 9.7 1.9 1.1 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 Ribosomal_L7Ae PF01248.26 CRK25545.1 - 7.4e-07 28.8 0.0 7.5e-07 28.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family GST_N_4 PF17172.4 CRK25546.1 - 2.1e-12 47.6 0.0 3e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 CRK25546.1 - 0.00086 19.6 0.3 0.008 16.5 0.2 2.1 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein SAM35 PF10806.8 CRK25546.1 - 0.0093 16.2 0.3 0.029 14.6 0.1 2.0 1 1 1 2 2 2 1 SAM35, subunit of SAM coomplex IDO PF01231.18 CRK25547.1 - 4.7e-33 114.6 0.0 6.3e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase INO80_Ies4 PF08193.11 CRK25549.1 - 1e-75 254.9 23.7 1e-75 254.9 23.7 2.4 2 1 1 3 3 3 1 INO80 complex subunit Ies4 CLTH PF10607.9 CRK25549.1 - 1.5e-29 102.8 0.0 2.5e-29 102.1 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 CRK25549.1 - 1.4e-24 86.5 0.2 2.6e-24 85.6 0.2 1.4 1 0 0 1 1 1 1 SPRY domain LisH PF08513.11 CRK25549.1 - 7.3e-06 25.7 0.2 1.7e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 LisH MFS_1 PF07690.16 CRK25550.1 - 7.6e-46 156.7 33.0 1.2e-45 156.0 33.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK25550.1 - 1.1e-09 37.7 10.5 1.1e-09 37.7 10.5 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 CRK25550.1 - 8e-06 25.4 7.1 8e-06 25.4 7.1 3.2 1 1 2 3 3 3 2 Uncharacterised MFS-type transporter YbfB MFS_3 PF05977.13 CRK25550.1 - 0.016 13.6 9.6 0.024 13.0 9.6 1.2 1 0 0 1 1 1 0 Transmembrane secretion effector Transgly_assoc PF04226.13 CRK25550.1 - 1.3 9.3 6.7 1.6 9.1 3.9 2.7 2 0 0 2 2 2 0 Transglycosylase associated protein IlvN PF07991.12 CRK25552.1 - 3e-27 95.2 0.4 1.1e-26 93.4 0.0 2.0 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Fungal_TACC PF12709.7 CRK25552.1 - 3.1e-13 49.9 19.7 1.2e-09 38.4 0.4 5.0 5 1 1 6 6 6 3 Fungal Transforming acidic coiled-coil (TACC) proteins DUF5101 PF17031.5 CRK25552.1 - 0.0078 16.3 7.7 3 8.0 0.0 4.2 3 2 0 3 3 3 2 Domain of unknown function (DUF5101) F420_oxidored PF03807.17 CRK25552.1 - 0.054 14.1 1.8 0.3 11.7 0.0 3.2 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent SHE3 PF17078.5 CRK25552.1 - 1.8 8.2 26.1 0.047 13.4 6.8 3.2 2 1 1 3 3 3 0 SWI5-dependent HO expression protein 3 DnaJ PF00226.31 CRK25553.1 - 5.2e-07 29.7 0.2 2.1e-06 27.8 0.2 1.9 1 1 0 1 1 1 1 DnaJ domain GatB_N PF02934.15 CRK25554.1 - 6.9e-98 327.4 0.0 9.9e-98 326.9 0.0 1.2 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 CRK25554.1 - 3.8e-09 36.6 0.4 1.7e-08 34.5 0.0 2.0 2 0 0 2 2 2 1 GatB domain PaaA_PaaC PF05138.12 CRK25554.1 - 0.076 12.2 0.2 0.21 10.7 0.0 1.7 2 0 0 2 2 2 0 Phenylacetic acid catabolic protein DUF2802 PF10975.8 CRK25555.1 - 0.11 12.7 0.7 0.24 11.5 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) DUF1961 PF09224.11 CRK25557.1 - 2.6e-64 216.5 0.0 2.9e-64 216.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1961) DUF515 PF04415.12 CRK25559.1 - 0.3 9.4 2.3 0.41 9.0 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) FGGY_C PF02782.16 CRK25574.1 - 2e-19 70.1 0.6 2.3e-19 69.9 0.6 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain eIF_4G1 PF12152.8 CRK25584.1 - 7.1e-24 83.8 1.1 1.7e-23 82.5 1.1 1.7 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 Aquarius_N PF16399.5 CRK25585.1 - 0 1064.8 0.0 0 1064.4 0.0 1.1 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_12 PF13087.6 CRK25585.1 - 7.1e-27 94.3 0.0 1.1e-26 93.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CRK25585.1 - 2.8e-21 76.5 0.0 9.1e-21 74.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CRK25585.1 - 2.2e-07 30.8 0.0 0.00076 19.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain ResIII PF04851.15 CRK25585.1 - 1.7e-05 24.9 0.0 3.9e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 CRK25585.1 - 1.7e-05 25.2 0.0 4.1e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CRK25585.1 - 0.0017 18.8 0.3 0.013 15.9 0.0 2.5 2 1 0 3 3 3 1 AAA ATPase domain Viral_helicase1 PF01443.18 CRK25585.1 - 0.0024 17.7 0.4 0.12 12.1 0.0 2.9 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA PF00004.29 CRK25585.1 - 0.0039 17.6 0.0 0.0092 16.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.15 CRK25585.1 - 0.0051 16.2 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain DUF2075 PF09848.9 CRK25585.1 - 0.016 14.4 0.4 0.033 13.4 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 CRK25585.1 - 0.024 14.9 0.1 0.15 12.4 0.0 2.3 1 1 1 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 CRK25585.1 - 0.059 12.4 0.0 0.098 11.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 SMC_N PF02463.19 CRK25585.1 - 0.074 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 CRK25585.1 - 0.092 13.0 0.0 2.1 8.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 CRK25585.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase Zeta_toxin PF06414.12 CRK25585.1 - 0.12 11.7 0.0 0.26 10.5 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin UvrD_C_2 PF13538.6 CRK25585.1 - 0.17 11.8 1.0 0.75 9.7 0.2 2.3 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain efThoc1 PF11957.8 CRK25586.1 - 5.3e-126 421.2 0.8 8e-126 420.6 0.8 1.2 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Guanylate_kin PF00625.21 CRK25586.1 - 4.1e-33 114.6 0.0 8.8e-33 113.5 0.0 1.6 1 0 0 1 1 1 1 Guanylate kinase MMR_HSR1 PF01926.23 CRK25586.1 - 0.00096 19.2 0.0 0.0023 18.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 CRK25586.1 - 0.0082 16.5 0.0 0.04 14.3 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 CRK25586.1 - 0.064 13.8 0.1 0.29 11.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 CRK25586.1 - 0.077 13.3 0.0 0.39 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 CRK25586.1 - 0.13 12.1 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain LON_substr_bdg PF02190.16 CRK25587.1 - 2.3e-25 89.7 0.0 3.1e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 CRK25587.1 - 1.5e-13 50.3 17.9 3.7e-11 42.7 9.8 2.8 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CRK25587.1 - 2.1e-10 40.4 23.1 1.2e-08 34.8 5.4 3.2 2 1 1 3 3 3 2 RING-type zinc-finger zf-C3HC4_4 PF15227.6 CRK25587.1 - 2.3e-10 40.5 22.8 2e-05 24.6 11.2 2.6 2 0 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 CRK25587.1 - 4e-09 36.2 15.6 2.7e-07 30.3 6.8 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CRK25587.1 - 7.2e-09 35.4 17.1 2.7e-06 27.2 8.9 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CRK25587.1 - 3.7e-08 33.2 20.6 6.2e-06 26.1 8.8 2.5 2 0 0 2 2 2 2 zinc-RING finger domain zf-RING_2 PF13639.6 CRK25587.1 - 4e-08 33.5 22.6 5.4e-07 29.8 9.7 2.8 2 0 0 2 2 2 2 Ring finger domain Prok-RING_4 PF14447.6 CRK25587.1 - 2.6e-05 24.0 18.2 0.00015 21.6 7.6 2.6 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 CRK25587.1 - 0.00042 20.0 6.3 0.00065 19.4 2.2 2.7 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 CRK25587.1 - 0.0085 16.4 4.6 0.0085 16.4 4.6 2.4 3 0 0 3 3 3 1 RING-H2 zinc finger domain U-box PF04564.15 CRK25587.1 - 0.033 14.3 0.0 0.47 10.7 0.0 2.4 2 0 0 2 2 2 0 U-box domain zf-RING_10 PF16685.5 CRK25587.1 - 0.087 13.0 17.1 0.032 14.3 6.6 2.4 2 0 0 2 2 2 0 zinc RING finger of MSL2 DUF775 PF05603.12 CRK25587.1 - 0.16 11.5 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF775) DZR PF12773.7 CRK25587.1 - 8 6.6 13.0 0.41 10.7 0.6 3.0 3 1 1 4 4 3 0 Double zinc ribbon INSIG PF07281.12 CRK25588.1 - 2e-85 285.8 1.2 3.8e-85 284.8 1.2 1.5 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) WD40 PF00400.32 CRK25588.1 - 0.0014 19.4 0.0 0.44 11.5 0.0 3.3 3 0 0 3 3 3 1 WD domain, G-beta repeat DUF4638 PF15472.6 CRK25588.1 - 0.064 13.0 0.4 0.14 11.9 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) DUF1749 PF08538.10 CRK25589.1 - 1.3e-81 274.0 0.0 1.5e-81 273.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Hydrolase_4 PF12146.8 CRK25589.1 - 4.8e-08 32.6 0.0 6.4e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CRK25589.1 - 1.5e-07 32.3 0.2 1.9e-07 31.9 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CRK25589.1 - 1.4e-06 28.2 0.1 4.5e-06 26.5 0.0 1.8 1 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CRK25589.1 - 0.00014 21.4 0.1 0.02 14.4 0.1 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.11 CRK25589.1 - 0.013 15.4 0.0 0.27 11.1 0.0 2.3 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 CRK25589.1 - 0.045 13.3 0.0 2.4 7.7 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_8 PF06259.12 CRK25589.1 - 0.082 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase LIDHydrolase PF10230.9 CRK25589.1 - 0.21 11.1 0.1 0.99 8.9 0.0 1.9 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase zf-C2H2 PF00096.26 CRK25590.1 - 0.0075 16.7 4.0 0.21 12.1 0.1 3.1 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CRK25590.1 - 0.013 16.2 3.5 8.8 7.5 1.2 3.4 2 0 0 2 2 2 0 C2H2-type zinc finger DUF753 PF05444.12 CRK25590.1 - 0.043 13.8 3.4 0.072 13.1 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF753) Zn_clus PF00172.18 CRK25591.1 - 6.5e-09 35.8 7.6 1.1e-08 35.0 7.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain KTI12 PF08433.10 CRK25592.1 - 3.8e-62 210.2 0.0 1.1e-61 208.7 0.0 1.8 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 CRK25592.1 - 0.0036 17.5 0.0 0.0086 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain PalH PF08733.10 CRK25593.1 - 3.6e-95 318.8 0.7 5.3e-95 318.2 0.7 1.1 1 0 0 1 1 1 1 PalH/RIM21 TRAM_LAG1_CLN8 PF03798.16 CRK25593.1 - 4.4e-10 39.6 19.6 4.4e-10 39.6 19.6 2.0 2 1 0 2 2 2 1 TLC domain CAAD PF14159.6 CRK25593.1 - 0.033 14.0 0.5 0.41 10.5 0.1 2.8 2 0 0 2 2 2 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase DUF3964 PF13107.6 CRK25593.1 - 0.17 12.3 0.0 0.29 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3964) HSP70 PF00012.20 CRK25595.1 - 4.3e-49 167.2 0.3 5e-49 167.0 0.3 1.1 1 0 0 1 1 1 1 Hsp70 protein NADH-G_4Fe-4S_3 PF10588.9 CRK25596.1 - 3.4e-18 64.9 0.2 3.4e-18 64.9 0.2 2.4 3 0 0 3 3 3 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2_4 PF13510.6 CRK25596.1 - 5e-09 36.1 0.9 1.5e-08 34.6 0.3 2.0 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer2 PF00111.27 CRK25596.1 - 0.011 15.7 1.9 0.1 12.5 0.2 2.3 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Fer4_6 PF12837.7 CRK25596.1 - 0.059 13.5 1.0 0.059 13.5 1.0 2.5 3 0 0 3 3 3 0 4Fe-4S binding domain zf-C2HE PF16278.5 CRK25596.1 - 0.059 13.8 0.0 2.7 8.5 0.0 2.2 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Opy2 PF09463.10 CRK25596.1 - 0.11 12.8 0.8 0.11 12.8 0.8 2.7 3 0 0 3 3 3 0 Opy2 protein Fer4_4 PF12800.7 CRK25596.1 - 0.16 12.5 1.6 0.16 12.5 1.6 3.0 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_8 PF13183.6 CRK25596.1 - 0.68 10.4 6.6 2 9.0 6.6 1.8 1 1 0 1 1 1 0 4Fe-4S dicluster domain AMP-binding PF00501.28 CRK25603.1 - 1.8e-09 36.7 0.0 1.8e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme peroxidase PF00141.23 CRK25628.1 - 2.2e-20 73.3 0.3 3.8e-20 72.6 0.3 1.3 1 0 0 1 1 1 1 Peroxidase Acyl_transf_3 PF01757.22 CRK25630.1 - 1.9e-36 125.8 16.0 2.7e-36 125.3 16.0 1.3 1 0 0 1 1 1 1 Acyltransferase family CReP_N PF10472.9 CRK25630.1 - 0.048 12.5 0.2 0.074 11.9 0.2 1.2 1 0 0 1 1 1 0 eIF2-alpha phosphatase phosphorylation constitutive repressor Glyco_hydro_43 PF04616.14 CRK25631.1 - 8.7e-19 67.9 0.7 1.1e-18 67.6 0.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_43 PF04616.14 CRK25632.1 - 5.2e-55 186.8 3.3 6.5e-55 186.5 3.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Methyltr_RsmB-F PF01189.17 CRK25634.1 - 3e-18 66.2 0.0 3.6e-11 43.1 0.0 2.4 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F DUF1996 PF09362.10 CRK25635.1 - 1.9e-60 204.8 0.5 3.5e-60 203.9 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Bac_rhamnosid6H PF17389.2 CRK25636.1 - 1e-16 61.2 0.1 1.8e-16 60.3 0.1 1.4 1 1 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Glyco_hydro_36 PF17167.4 CRK25636.1 - 0.017 13.8 0.0 0.029 13.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase 36 superfamily, catalytic domain Glyco_hydro_2_N PF02837.18 CRK25636.1 - 0.031 14.2 0.0 0.069 13.1 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_79C PF16862.5 CRK25637.1 - 2.1e-21 76.8 2.5 2.1e-21 76.8 2.5 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 79 C-terminal beta domain Caudal_act PF04731.12 CRK25637.1 - 0.029 14.7 2.9 0.054 13.8 0.3 2.4 2 0 0 2 2 2 0 Caudal like protein activation region Sugar_tr PF00083.24 CRK25638.1 - 5.5e-69 233.2 21.3 6.7e-69 232.9 21.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK25638.1 - 3.6e-20 72.2 37.9 1.1e-15 57.4 21.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Rep_N PF08724.10 CRK25638.1 - 0.09 12.5 0.1 0.17 11.6 0.1 1.4 1 0 0 1 1 1 0 Rep protein catalytic domain like DUF454 PF04304.13 CRK25638.1 - 0.79 9.7 0.0 0.79 9.7 0.0 3.6 4 1 1 5 5 5 0 Protein of unknown function (DUF454) Epimerase PF01370.21 CRK25639.1 - 0.0022 17.5 0.0 0.0038 16.7 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Metallophos PF00149.28 CRK25640.1 - 7.2e-17 62.6 2.5 1.1e-16 61.9 2.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CRK25640.1 - 3.4e-05 24.1 0.1 8.1e-05 22.9 0.0 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain CbiG_mid PF11761.8 CRK25640.1 - 0.027 14.6 0.0 0.059 13.5 0.0 1.6 1 0 0 1 1 1 0 Cobalamin biosynthesis central region WAC_Acf1_DNA_bd PF10537.9 CRK25641.1 - 8.2e-39 132.2 0.0 1.6e-38 131.3 0.0 1.5 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.17 CRK25641.1 - 1.7e-16 60.2 1.3 2.9e-16 59.5 1.3 1.4 1 0 0 1 1 1 1 DDT domain DUF4611 PF15387.6 CRK25641.1 - 0.0017 18.6 1.8 0.0041 17.3 1.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4611) Alg6_Alg8 PF03155.15 CRK25642.1 - 5.3e-90 302.7 10.7 6.8e-90 302.4 10.7 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Lectin_leg-like PF03388.13 CRK25643.1 - 8.6e-22 77.6 0.0 1.3e-21 77.0 0.0 1.3 1 0 0 1 1 1 1 Legume-like lectin family Gly_rich PF12810.7 CRK25643.1 - 0.013 15.4 7.4 0.013 15.4 7.4 2.0 2 0 0 2 2 2 0 Glycine rich protein UPF0242 PF06785.11 CRK25643.1 - 0.015 15.4 0.1 0.021 14.9 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Fib_alpha PF08702.10 CRK25643.1 - 0.08 13.1 0.4 0.08 13.1 0.4 1.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF1515 PF07439.11 CRK25643.1 - 0.16 12.0 0.6 0.31 11.1 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) AAA_13 PF13166.6 CRK25643.1 - 3.7 6.1 6.9 0.066 11.8 0.4 1.3 2 0 0 2 2 2 0 AAA domain UbiA PF01040.18 CRK25671.1 - 0.002 17.5 1.6 0.0021 17.4 1.6 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family PAP2 PF01569.21 CRK25671.1 - 0.0041 16.9 0.8 0.0062 16.3 0.8 1.3 1 0 0 1 1 1 1 PAP2 superfamily GMC_oxred_N PF00732.19 CRK25672.1 - 1.8e-15 57.1 0.0 2.6e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CRK25672.1 - 2.5e-09 37.8 0.0 4.3e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase LIM_bind PF01803.16 CRK25673.1 - 1.5e-75 253.9 0.0 1.5e-75 253.9 0.0 5.0 3 1 0 3 3 3 1 LIM-domain binding protein HbrB PF08539.11 CRK25674.1 - 9.6e-53 178.6 0.0 2.4e-52 177.3 0.0 1.7 1 0 0 1 1 1 1 HbrB-like SPX PF03105.19 CRK25675.1 - 1.5e-37 130.4 13.6 8.3e-27 95.1 0.0 4.2 4 1 1 5 5 5 2 SPX domain Vps39_1 PF10366.9 CRK25675.1 - 2.8e-33 114.4 0.0 1.5e-32 112.1 0.0 2.4 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 1 Na_sulph_symp PF00939.19 CRK25675.1 - 3e-33 115.6 44.3 1e-24 87.4 29.8 2.1 1 1 1 2 2 2 2 Sodium:sulfate symporter transmembrane region Vps39_2 PF10367.9 CRK25675.1 - 4.5e-29 101.1 0.0 1.4e-28 99.5 0.0 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CitMHS PF03600.16 CRK25675.1 - 6.9e-23 81.3 46.2 1.9e-22 79.9 40.8 3.4 1 1 2 3 3 3 3 Citrate transporter CNH PF00780.22 CRK25675.1 - 1.3e-12 47.9 0.0 2.6e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 CNH domain Clathrin PF00637.20 CRK25675.1 - 0.056 13.3 0.1 0.056 13.3 0.1 2.6 3 0 0 3 3 3 0 Region in Clathrin and VPS Pyr_redox_2 PF07992.14 CRK25677.1 - 2.7e-19 69.5 0.0 6.5e-19 68.3 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CRK25677.1 - 1.2e-13 51.4 0.1 3.4e-12 46.8 0.2 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CRK25677.1 - 0.0006 19.0 0.1 0.0011 18.1 0.0 1.4 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 CRK25677.1 - 0.0023 17.2 0.1 0.0056 16.0 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TMP-TENI PF02581.17 CRK25677.1 - 0.013 14.8 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Thiamine monophosphate synthase K_oxygenase PF13434.6 CRK25677.1 - 0.018 14.2 0.0 0.031 13.4 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) TrkA_N PF02254.18 CRK25677.1 - 0.03 14.6 0.0 1.4 9.2 0.1 2.4 2 0 0 2 2 2 0 TrkA-N domain Trp_halogenase PF04820.14 CRK25677.1 - 0.04 12.8 0.0 0.5 9.2 0.2 2.0 2 0 0 2 2 2 0 Tryptophan halogenase adh_short PF00106.25 CRK25677.1 - 0.043 13.3 0.2 0.091 12.2 0.2 1.5 1 0 0 1 1 1 0 short chain dehydrogenase Amino_oxidase PF01593.24 CRK25677.1 - 0.044 13.1 0.0 0.07 12.4 0.0 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase DAO PF01266.24 CRK25677.1 - 0.062 12.9 2.1 0.37 10.3 0.1 2.7 2 1 1 3 3 3 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 CRK25677.1 - 0.11 13.0 0.1 0.33 11.4 0.1 1.9 1 0 0 1 1 1 0 Putative NAD(P)-binding HI0933_like PF03486.14 CRK25677.1 - 2.3 6.9 4.7 1.1 7.9 0.3 2.2 2 1 1 3 3 3 0 HI0933-like protein Acetyltransf_8 PF13523.6 CRK25678.1 - 3.2e-46 156.6 3.1 4.6e-46 156.1 3.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 CRK25678.1 - 0.039 14.6 0.3 0.094 13.4 0.3 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain AMP-binding PF00501.28 CRK25679.1 - 6.4e-97 324.8 0.0 8.6e-97 324.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CRK25679.1 - 2.2e-12 47.8 0.0 5.8e-12 46.4 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 CRK25680.1 - 8.3e-67 225.6 0.2 8.8e-56 189.3 0.0 3.1 3 0 0 3 3 3 2 AMP-binding enzyme Condensation PF00668.20 CRK25680.1 - 1.6e-57 195.2 0.0 6e-34 117.5 0.0 3.5 3 1 0 3 3 3 3 Condensation domain PP-binding PF00550.25 CRK25680.1 - 1.4e-27 95.8 0.2 3.2e-12 46.6 0.1 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site p450 PF00067.22 CRK25681.1 - 6.1e-34 117.5 0.0 7.9e-34 117.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3425 PF11905.8 CRK25681.1 - 9e-10 38.6 2.5 1.6e-09 37.8 2.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 CRK25681.1 - 0.13 12.4 0.3 0.29 11.3 0.2 1.6 1 1 1 2 2 2 0 bZIP transcription factor p450 PF00067.22 CRK25682.1 - 4.3e-21 75.2 0.0 5.5e-21 74.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.26 CRK25683.1 - 3.5e-19 69.1 0.6 5.4e-19 68.4 0.6 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CRK25683.1 - 2.6e-16 59.4 0.4 7.4e-16 58.0 0.1 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 CRK25683.1 - 0.0047 18.0 0.0 0.0084 17.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 CRK25683.1 - 0.025 14.0 0.5 0.053 13.0 0.5 1.6 1 0 0 1 1 1 0 short chain dehydrogenase ADH_N_2 PF16884.5 CRK25683.1 - 0.15 12.0 0.0 0.99 9.3 0.0 2.1 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase Aldedh PF00171.22 CRK25684.1 - 2.7e-144 481.1 0.3 3.3e-144 480.8 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LTXXQ PF07813.12 CRK25684.1 - 0.076 13.7 0.2 0.16 12.7 0.2 1.5 1 0 0 1 1 1 0 LTXXQ motif family protein DUF917 PF06032.12 CRK25685.1 - 3.9e-96 322.0 0.0 5.6e-65 219.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF917) Hydant_A_N PF05378.13 CRK25685.1 - 3.3e-26 92.1 10.0 1.1e-24 87.1 0.2 3.7 4 1 0 4 4 4 2 Hydantoinase/oxoprolinase N-terminal region Hydantoinase_A PF01968.18 CRK25685.1 - 8.9e-23 81.0 13.6 1.7e-19 70.2 3.7 4.3 2 1 1 3 3 3 2 Hydantoinase/oxoprolinase MutL PF13941.6 CRK25685.1 - 2.6e-05 23.0 2.2 0.075 11.6 0.0 2.4 2 0 0 2 2 2 2 MutL protein StbA PF06406.11 CRK25685.1 - 0.00027 20.3 0.2 0.15 11.3 0.0 2.4 2 0 0 2 2 2 2 StbA protein BcrAD_BadFG PF01869.20 CRK25685.1 - 0.022 14.3 6.6 0.27 10.7 0.5 2.8 2 1 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family YadA_anchor PF03895.15 CRK25685.1 - 0.17 12.0 0.6 0.76 9.9 0.1 2.3 2 0 0 2 2 2 0 YadA-like membrane anchor domain FtsA PF14450.6 CRK25685.1 - 1 9.8 6.3 13 6.2 0.1 3.7 3 1 0 3 3 3 0 Cell division protein FtsA Transp_cyt_pur PF02133.15 CRK25686.1 - 4.5e-90 302.5 33.0 5.2e-90 302.3 33.0 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin LRR_4 PF12799.7 CRK25687.1 - 2.3e-17 62.8 24.8 2.6e-05 24.5 0.1 3.9 2 1 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CRK25687.1 - 4e-15 55.3 9.0 9.3e-12 44.5 0.2 3.7 2 1 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.33 CRK25687.1 - 1.2e-12 46.5 2.3 0.91 10.3 0.0 5.5 5 0 0 5 5 5 4 Leucine Rich Repeat LRR_6 PF13516.6 CRK25687.1 - 1.5e-07 30.9 11.6 0.038 14.1 0.2 4.9 5 0 0 5 5 5 4 Leucine Rich repeat adh_short PF00106.25 CRK25688.1 - 6.5e-18 64.9 0.1 7.1e-18 64.8 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK25688.1 - 2.8e-13 50.0 0.1 3.3e-13 49.7 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK25688.1 - 1.3e-10 41.4 0.3 1.5e-10 41.2 0.3 1.0 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CRK25688.1 - 0.0015 18.1 0.1 0.0017 17.9 0.1 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PALP PF00291.25 CRK25688.1 - 0.019 14.4 0.2 0.021 14.2 0.2 1.0 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme RmlD_sub_bind PF04321.17 CRK25688.1 - 0.045 12.9 0.1 0.056 12.5 0.1 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 CRK25688.1 - 0.085 12.2 0.0 0.094 12.1 0.0 1.0 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DUF1815 PF08844.10 CRK25688.1 - 0.086 12.8 0.0 0.13 12.2 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1815) NmrA PF05368.13 CRK25688.1 - 0.23 11.0 0.6 0.4 10.2 0.5 1.4 1 1 1 2 2 2 0 NmrA-like family DUF1996 PF09362.10 CRK25713.1 - 2.1e-43 149.0 0.1 2.6e-43 148.7 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) SAT PF16073.5 CRK25714.1 - 4.4e-77 259.0 2.5 1.2e-76 257.7 2.5 1.8 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis ketoacyl-synt PF00109.26 CRK25714.1 - 1.9e-74 250.5 0.0 3.9e-74 249.4 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 CRK25714.1 - 2.9e-45 155.1 0.0 6.6e-45 154.0 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 CRK25714.1 - 3.8e-36 123.7 0.4 7.8e-36 122.7 0.4 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.20 CRK25714.1 - 6e-23 82.2 0.0 2.4e-22 80.2 0.0 2.0 2 0 0 2 2 2 1 Thioesterase domain PP-binding PF00550.25 CRK25714.1 - 2.3e-21 75.9 4.8 4.7e-11 42.9 0.2 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.6 CRK25714.1 - 3.2e-15 56.2 0.0 6e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 CRK25714.1 - 0.00013 22.4 0.0 0.00035 21.0 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 CRK25714.1 - 0.00028 20.4 0.1 0.0022 17.4 0.0 2.3 2 0 0 2 2 2 1 Thiolase, N-terminal domain Abhydrolase_6 PF12697.7 CRK25714.1 - 0.00029 21.5 1.5 0.48 11.0 0.1 3.1 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CRK25714.1 - 0.0025 17.5 0.0 0.019 14.6 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CRK25714.1 - 0.047 12.9 0.0 1.8 7.8 0.0 2.5 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Cu-oxidase_3 PF07732.15 CRK25715.1 - 3e-42 143.4 7.1 9.1e-41 138.6 1.6 3.0 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 CRK25715.1 - 4.7e-40 136.5 10.6 5.5e-36 123.3 1.3 3.7 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 CRK25715.1 - 3.3e-27 95.6 0.4 9.3e-25 87.6 0.1 2.8 3 0 0 3 3 3 2 Multicopper oxidase DUF92 PF01940.16 CRK25718.1 - 8.1e-65 218.5 0.5 1.1e-60 205.1 0.0 2.1 1 1 1 2 2 2 2 Integral membrane protein DUF92 CTP_transf_1 PF01148.20 CRK25718.1 - 0.0063 16.3 2.8 0.013 15.3 2.8 1.4 1 0 0 1 1 1 1 Cytidylyltransferase family Pyridoxal_deC PF00282.19 CRK25719.1 - 8e-19 67.6 0.0 1.4e-13 50.4 0.0 2.1 1 1 1 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain NAD_binding_4 PF07993.12 CRK25720.1 - 1e-10 41.3 0.0 1.5e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein adh_short_C2 PF13561.6 CRK25721.1 - 2e-48 165.0 0.1 4.9e-48 163.7 0.1 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRK25721.1 - 8e-47 159.2 0.6 8e-47 159.2 0.6 1.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 CRK25721.1 - 1.3e-08 34.9 0.5 2.8e-08 33.9 0.5 1.4 1 0 0 1 1 1 1 KR domain PPR_2 PF13041.6 CRK25721.1 - 1.4e-07 31.5 0.0 0.19 11.9 0.0 4.4 2 1 2 4 4 4 2 PPR repeat family PPR PF01535.20 CRK25721.1 - 0.00096 19.3 0.1 0.13 12.5 0.0 3.5 3 0 0 3 3 3 1 PPR repeat PPR_3 PF13812.6 CRK25721.1 - 0.0012 18.9 0.0 0.59 10.3 0.0 3.9 4 0 0 4 4 4 1 Pentatricopeptide repeat domain PPR_long PF17177.4 CRK25721.1 - 0.042 13.2 0.0 17 4.7 0.0 3.1 2 1 1 3 3 3 0 Pentacotripeptide-repeat region of PRORP Ribosomal_S18 PF01084.20 CRK25722.1 - 7.1e-12 45.4 0.0 1.2e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S18 Mito_carr PF00153.27 CRK25723.1 - 3.1e-53 177.7 0.5 1.1e-17 63.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L22e PF01776.17 CRK25724.1 - 3.1e-46 156.2 1.6 3.8e-46 156.0 1.6 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family START PF01852.19 CRK25724.1 - 0.011 15.1 0.0 0.016 14.7 0.0 1.1 1 0 0 1 1 1 0 START domain NmrA PF05368.13 CRK25725.1 - 2.6e-08 33.7 0.0 8.3e-08 32.1 0.0 1.8 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 CRK25725.1 - 5.6e-07 29.6 0.0 1.4e-06 28.4 0.0 1.8 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 CRK25725.1 - 0.089 13.1 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 CRK25725.1 - 0.094 12.8 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 CRK25725.1 - 0.14 11.8 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Hydantoinase_B PF02538.14 CRK25726.1 - 4.2e-199 662.2 1.1 1.5e-130 436.0 0.1 2.2 1 1 1 2 2 2 2 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 CRK25726.1 - 7.1e-104 347.1 1.2 1.3e-103 346.3 1.2 1.5 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 CRK25726.1 - 1.5e-60 204.0 2.2 3.8e-59 199.4 0.1 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region PXA PF02194.15 CRK25727.1 - 8.8e-34 117.1 0.2 2.4e-33 115.6 0.2 1.8 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.12 CRK25727.1 - 3.5e-24 85.5 0.1 1.5e-23 83.5 0.1 2.2 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.24 CRK25727.1 - 3.8e-06 26.9 0.1 1.4e-05 25.0 0.0 2.0 2 0 0 2 2 2 1 PX domain DUF724 PF05266.14 CRK25727.1 - 5 6.9 9.8 56 3.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF724) PC4 PF02229.16 CRK25728.1 - 3.1e-23 81.1 0.1 5.1e-23 80.5 0.1 1.4 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) DUF3824 PF12868.7 CRK25729.1 - 0.00017 22.3 49.3 0.00017 22.3 49.3 3.2 2 1 0 2 2 2 1 Domain of unknwon function (DUF3824) Actin PF00022.19 CRK25730.1 - 2.1e-71 240.7 0.0 1.2e-70 238.2 0.0 1.8 1 1 0 1 1 1 1 Actin HEAT_PBS PF03130.16 CRK25731.1 - 0.0064 17.1 0.1 0.028 15.1 0.1 2.0 2 1 0 2 2 2 1 PBS lyase HEAT-like repeat HEAT_2 PF13646.6 CRK25731.1 - 0.056 13.8 0.1 0.076 13.4 0.1 1.3 1 0 0 1 1 1 0 HEAT repeats HEAT_EZ PF13513.6 CRK25731.1 - 0.066 13.7 0.5 0.51 10.9 0.4 1.9 1 1 1 2 2 2 0 HEAT-like repeat Ribosomal_L26 PF16906.5 CRK25732.1 - 1.5e-14 54.2 0.2 1.8e-14 54.0 0.2 1.2 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 CRK25732.1 - 4.6e-07 29.6 1.8 4.6e-07 29.6 1.8 2.4 3 0 0 3 3 3 1 KOW motif Acetyltransf_1 PF00583.25 CRK25734.1 - 0.053 13.8 0.0 0.053 13.7 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family LSM14 PF12701.7 CRK25734.1 - 0.17 12.0 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 Scd6-like Sm domain Dis3l2_C_term PF17877.1 CRK25738.1 - 1.7e-20 73.1 0.0 2.5e-20 72.6 0.0 1.3 1 1 0 1 1 1 1 DIS3-like exonuclease 2 C terminal CBP4 PF07960.11 CRK25738.1 - 0.019 14.8 2.0 0.023 14.6 2.0 1.2 1 0 0 1 1 1 0 CBP4 Sec23_trunk PF04811.15 CRK25757.1 - 9.2e-80 267.7 0.0 1.3e-79 267.2 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 CRK25757.1 - 7.5e-31 106.7 0.2 1.4e-30 105.9 0.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 CRK25757.1 - 7.6e-26 89.9 0.3 4.5e-25 87.5 0.1 2.3 2 0 0 2 2 2 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 CRK25757.1 - 4.9e-14 52.1 8.8 9.3e-14 51.2 8.8 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 CRK25757.1 - 5.3e-12 45.5 0.0 1.6e-11 43.9 0.0 1.9 2 0 0 2 2 2 1 Gelsolin repeat Vps36-NZF-N PF16988.5 CRK25757.1 - 0.036 13.5 1.3 0.066 12.6 0.1 1.9 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Ribosomal_L11_N PF03946.14 CRK25758.1 - 8.6e-25 86.4 0.2 1.4e-24 85.7 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 CRK25758.1 - 2.9e-16 59.7 0.1 4.9e-16 59.0 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Colicin PF01024.19 CRK25758.1 - 0.12 12.3 0.1 0.4 10.5 0.0 1.8 2 1 0 2 2 2 0 Colicin pore forming domain TPR_2 PF07719.17 CRK25759.1 - 2e-09 36.8 0.1 0.012 15.7 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 CRK25759.1 - 1.9e-08 33.7 0.0 0.037 13.9 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 CRK25759.1 - 0.00012 21.8 0.1 0.021 14.7 0.2 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 CRK25759.1 - 0.00065 19.7 0.1 26 5.4 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 CRK25759.1 - 0.0011 18.6 0.0 1.2 8.9 0.0 3.2 2 1 1 3 3 3 2 TPR repeat TPR_12 PF13424.6 CRK25759.1 - 0.0055 17.0 0.7 0.12 12.7 0.1 2.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 CRK25759.1 - 0.022 15.1 0.1 0.068 13.6 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 CRK25759.1 - 0.094 13.6 1.5 25 6.1 0.2 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat Suppressor_APC PF11414.8 CRK25759.1 - 0.14 12.2 0.0 0.36 10.9 0.0 1.6 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein Glyco_transf_41 PF13844.6 CRK25761.1 - 2.7e-154 514.1 0.2 8.9e-52 176.1 0.0 6.0 2 2 2 5 5 5 4 Glycosyl transferase family 41 TPR_1 PF00515.28 CRK25761.1 - 3e-11 42.7 0.1 0.00064 19.4 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 CRK25761.1 - 1.4e-08 34.5 0.3 0.0031 17.8 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 CRK25761.1 - 5.9e-08 32.3 0.0 0.0025 17.9 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 CRK25761.1 - 7.3e-08 32.0 0.3 0.025 14.3 0.0 3.5 1 1 2 3 3 3 2 TPR repeat TPR_2 PF07719.17 CRK25761.1 - 8.1e-07 28.7 0.0 0.069 13.3 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 CRK25761.1 - 1.2e-06 28.1 0.1 0.012 15.6 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 CRK25761.1 - 2.7e-06 27.1 1.3 0.027 14.4 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 CRK25761.1 - 2.2e-05 24.9 0.0 0.2 12.6 0.0 3.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 CRK25761.1 - 5.3e-05 23.8 1.8 0.32 11.7 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CRK25761.1 - 6.2e-05 23.2 0.4 0.0016 18.7 0.3 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 CRK25761.1 - 0.00032 21.1 0.2 0.0092 16.5 0.2 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat DUF237 PF03072.14 CRK25761.1 - 0.013 15.5 0.0 9 6.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF237) Granulin PF00396.18 CRK25761.1 - 0.28 11.5 11.1 2.6 8.5 1.1 3.0 3 0 0 3 3 3 0 Granulin PEGSRP PF07623.11 CRK25762.1 - 0.95 9.3 4.2 4.9 7.1 0.3 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1584) T7SS_ESX_EspC PF10824.8 CRK25763.1 - 0.044 14.3 1.9 0.044 14.3 1.9 2.3 2 0 0 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm TarH PF02203.15 CRK25763.1 - 0.052 13.5 2.5 0.71 9.8 0.5 2.2 2 0 0 2 2 2 0 Tar ligand binding domain homologue DUF515 PF04415.12 CRK25763.1 - 5.5 5.3 7.5 8.3 4.7 7.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) SRP_TPR_like PF17004.5 CRK25764.1 - 1.5e-19 70.1 2.3 5.2e-17 61.9 0.8 2.7 2 0 0 2 2 2 2 Putative TPR-like repeat SRP72 PF08492.12 CRK25764.1 - 1.4e-15 57.4 8.8 1.4e-15 57.4 8.8 2.7 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_2 PF07719.17 CRK25764.1 - 0.00064 19.6 23.7 0.24 11.6 0.2 7.3 7 1 0 7 7 7 3 Tetratricopeptide repeat ANAPC3 PF12895.7 CRK25764.1 - 0.0095 16.1 10.4 0.04 14.1 1.6 3.9 4 1 0 4 4 3 1 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.20 CRK25764.1 - 0.03 14.5 0.5 52 4.4 0.0 4.8 5 0 0 5 5 5 0 PPR repeat TPR_12 PF13424.6 CRK25764.1 - 0.2 12.0 27.1 1.2 9.5 0.2 5.9 4 2 2 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 CRK25764.1 - 2.4 8.1 17.2 8.6 6.4 0.1 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 CRK25764.1 - 3.5 8.4 34.2 0.21 12.2 3.4 6.0 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.6 CRK25764.1 - 3.7 8.1 26.1 7.5 7.1 0.2 5.1 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_3 PF07720.12 CRK25764.1 - 5 7.2 9.1 23 5.1 0.5 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 CRK25764.1 - 7.9 6.8 21.2 1.2 9.3 0.2 5.5 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 CRK25764.1 - 8.5 7.5 31.7 3.2 8.8 0.1 7.6 7 2 2 9 9 8 0 Tetratricopeptide repeat Sec7 PF01369.20 CRK25765.1 - 3e-31 108.5 0.1 4.7e-31 107.9 0.1 1.2 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 CRK25765.1 - 7.7e-07 29.6 0.1 1.9e-06 28.4 0.1 1.7 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 CRK25765.1 - 0.00039 20.8 0.3 0.00088 19.6 0.3 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain Osmo_CC PF08946.10 CRK25765.1 - 4.3 7.7 7.4 0.81 10.0 2.8 2.2 2 0 0 2 2 2 0 Osmosensory transporter coiled coil Peptidase_M14 PF00246.24 CRK25766.1 - 1.6e-73 248.0 0.0 2e-73 247.7 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Aminotran_3 PF00202.21 CRK25767.1 - 6.8e-117 390.6 0.0 7.8e-117 390.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aldedh PF00171.22 CRK25768.1 - 3e-148 494.2 2.5 5.7e-94 315.2 0.8 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family Acetyltransf_6 PF13480.7 CRK25768.1 - 0.089 13.0 0.6 0.18 11.9 0.6 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain TPR_16 PF13432.6 CRK25768.1 - 3.2 8.5 5.9 0.44 11.2 1.2 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat SMC_N PF02463.19 CRK25769.1 - 4.3e-29 101.5 3.0 7.5e-29 100.7 2.9 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CRK25769.1 - 1.4e-06 28.4 3.1 0.00032 20.6 2.7 2.6 1 1 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system Spc7 PF08317.11 CRK25769.1 - 0.00013 21.0 41.1 0.0027 16.6 16.6 3.6 2 1 0 3 3 3 3 Spc7 kinetochore protein ATG16 PF08614.11 CRK25769.1 - 0.00026 21.3 42.2 0.002 18.4 17.0 3.4 3 0 0 3 3 3 2 Autophagy protein 16 (ATG16) Fez1 PF06818.15 CRK25769.1 - 0.00047 20.7 36.6 0.039 14.4 16.0 3.3 2 1 1 3 3 3 2 Fez1 FlxA PF14282.6 CRK25769.1 - 0.013 15.5 0.3 0.013 15.5 0.3 4.0 4 1 0 4 4 4 0 FlxA-like protein ERM PF00769.19 CRK25769.1 - 0.037 13.8 44.4 0.0095 15.8 25.8 2.6 1 1 0 2 2 2 0 Ezrin/radixin/moesin family SbcCD_C PF13558.6 CRK25769.1 - 0.039 14.2 0.0 0.12 12.6 0.0 1.9 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit XhlA PF10779.9 CRK25769.1 - 0.04 14.1 0.8 0.04 14.1 0.8 5.8 5 2 1 6 6 5 0 Haemolysin XhlA DUF4988 PF16378.5 CRK25769.1 - 0.07 12.8 4.2 0.53 9.9 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function FPP PF05911.11 CRK25769.1 - 0.11 10.7 35.1 0.019 13.2 18.0 3.0 2 1 1 3 3 3 0 Filament-like plant protein, long coiled-coil Atg14 PF10186.9 CRK25769.1 - 0.37 9.8 35.9 0.034 13.2 16.8 3.1 2 1 1 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 Phage_GP20 PF06810.11 CRK25769.1 - 0.43 10.4 31.8 0.053 13.3 5.0 4.6 3 2 1 4 4 4 0 Phage minor structural protein GP20 Golgin_A5 PF09787.9 CRK25769.1 - 1.5 8.2 39.8 3.3 7.1 4.5 3.5 2 1 1 3 3 3 0 Golgin subfamily A member 5 Exonuc_VII_L PF02601.15 CRK25769.1 - 1.6 8.3 32.9 4 6.9 0.2 3.1 2 1 1 3 3 3 0 Exonuclease VII, large subunit DUF724 PF05266.14 CRK25769.1 - 1.7 8.4 32.0 0.18 11.6 15.4 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF724) Rab5-bind PF09311.11 CRK25769.1 - 1.9 7.8 37.0 0.024 14.0 7.2 4.3 2 1 2 4 4 4 0 Rabaptin-like protein Tropomyosin PF00261.20 CRK25769.1 - 2.3 7.5 44.5 0.046 13.1 4.6 4.3 3 1 1 4 4 4 0 Tropomyosin Laminin_II PF06009.12 CRK25769.1 - 3.3 7.7 23.2 0.16 11.9 4.6 4.5 3 2 1 4 4 4 0 Laminin Domain II CEP63 PF17045.5 CRK25769.1 - 3.8 7.3 37.8 1.4 8.7 24.4 3.4 2 1 1 3 3 3 0 Centrosomal protein of 63 kDa KELK PF15796.5 CRK25769.1 - 4.3 7.8 39.9 2.5 8.6 0.6 4.8 4 1 0 4 4 4 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF1664 PF07889.12 CRK25769.1 - 4.4 7.4 23.7 1.3 9.1 1.9 4.8 3 3 1 4 4 4 0 Protein of unknown function (DUF1664) DUF3584 PF12128.8 CRK25769.1 - 4.7 4.6 45.7 0.17 9.4 16.7 3.9 2 1 2 4 4 4 0 Protein of unknown function (DUF3584) OmpH PF03938.14 CRK25769.1 - 5.2 7.4 45.9 0.99 9.7 0.9 4.5 3 1 1 4 4 4 0 Outer membrane protein (OmpH-like) Filament PF00038.21 CRK25769.1 - 6.5 6.2 41.6 1.8 8.1 20.7 4.5 2 1 0 3 3 3 0 Intermediate filament protein DUF5320 PF17253.2 CRK25769.1 - 8.7 7.5 17.8 15 6.7 0.1 4.8 3 1 1 4 4 4 0 Family of unknown function (DUF5320) DUF2838 PF10998.8 CRK25770.1 - 1.6e-46 157.1 8.4 1.6e-46 157.1 8.4 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF2838) SMC_N PF02463.19 CRK25771.1 - 4.5e-21 75.3 11.9 4.5e-21 75.3 11.9 2.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CRK25771.1 - 2.3e-08 33.6 0.0 4.6e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 CRK25771.1 - 3.3e-07 31.0 51.9 1.4 9.4 52.0 3.4 1 1 0 1 1 1 1 AAA domain MscS_porin PF12795.7 CRK25771.1 - 3.3e-05 23.6 21.0 3.3e-05 23.6 21.0 2.6 2 1 0 2 2 2 1 Mechanosensitive ion channel porin domain AAA_15 PF13175.6 CRK25771.1 - 6.3e-05 22.8 16.9 6.3e-05 22.8 16.9 2.6 1 1 1 2 2 1 1 AAA ATPase domain AAA_21 PF13304.6 CRK25771.1 - 0.00061 19.7 10.9 0.0062 16.4 10.7 2.8 1 1 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system Spectrin PF00435.21 CRK25771.1 - 0.021 15.3 10.7 0.021 15.3 10.7 3.7 3 1 0 3 3 3 0 Spectrin repeat Spc7 PF08317.11 CRK25771.1 - 0.16 10.8 47.4 0.018 14.0 19.8 3.3 1 1 2 3 3 3 0 Spc7 kinetochore protein Laminin_II PF06009.12 CRK25771.1 - 0.2 11.6 29.1 0.033 14.2 2.3 4.2 1 1 2 4 4 4 0 Laminin Domain II ABC_tran PF00005.27 CRK25771.1 - 0.26 11.8 0.0 0.26 11.8 0.0 3.7 2 1 0 2 2 1 0 ABC transporter DUF3584 PF12128.8 CRK25771.1 - 0.61 7.5 47.6 0.89 7.0 47.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_13 PF13166.6 CRK25771.1 - 1 7.9 46.5 0.24 10.0 26.1 3.2 2 1 2 4 4 4 0 AAA domain Flagellin_C PF00700.21 CRK25771.1 - 1.1 9.6 9.3 0.55 10.6 0.5 3.5 3 0 0 3 3 3 0 Bacterial flagellin C-terminal helical region Lebercilin PF15619.6 CRK25771.1 - 1.9 8.1 55.1 0.66 9.6 19.0 4.2 1 1 2 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease DUF948 PF06103.11 CRK25771.1 - 2.8 8.3 12.4 23 5.3 1.4 3.8 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 CRK25771.1 - 2.9 8.0 26.1 0.21 11.6 2.6 4.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 CRK25771.1 - 4.1 7.9 17.6 3.2 8.2 1.5 4.5 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) SlyX PF04102.12 CRK25771.1 - 4.2 8.1 24.5 3.3 8.4 0.3 5.0 3 1 2 5 5 4 0 SlyX DUF2730 PF10805.8 CRK25771.1 - 4.8 7.3 14.5 0.49 10.5 1.0 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) DUF489 PF04356.12 CRK25771.1 - 5.6 6.9 12.6 1.5 8.8 0.9 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF489) Ribosomal_L7Ae PF01248.26 CRK25774.1 - 3.3e-17 62.0 0.4 4.1e-17 61.7 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF1846 PF08903.11 CRK25774.1 - 0.11 11.0 0.0 0.12 10.9 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1846) Methyltr_RsmB-F PF01189.17 CRK25777.1 - 1.6e-19 70.4 0.0 1.8e-19 70.2 0.0 1.0 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F TAF4 PF05236.14 CRK25779.1 - 0.59 9.8 5.4 0.058 13.1 0.9 1.5 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family YabA PF06156.13 CRK25779.1 - 5.5 7.7 5.1 3.9 8.2 0.2 2.3 1 1 1 2 2 2 0 Initiation control protein YabA CSG2 PF16965.5 CRK25780.1 - 0.016 14.2 2.4 0.017 14.1 2.4 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator Methyltransf_22 PF13383.6 CRK25797.1 - 8.8e-09 35.3 0.1 1e-08 35.1 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Flavodoxin_2 PF02525.17 CRK25798.1 - 5.6e-06 26.2 0.0 6.9e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 CRK25798.1 - 6.5e-06 26.0 0.0 8.2e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.25 CRK25798.1 - 0.0019 18.4 0.0 0.06 13.6 0.0 2.2 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 CRK25798.1 - 0.028 14.6 0.0 1 9.6 0.0 2.1 1 1 1 2 2 2 0 Flavodoxin domain DUF3328 PF11807.8 CRK25799.1 - 8e-24 84.6 0.1 1.1e-23 84.2 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Asp PF00026.23 CRK25800.1 - 2.9e-50 171.5 0.0 3.9e-50 171.1 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CRK25800.1 - 3.7e-09 37.1 0.1 2.3e-07 31.2 0.1 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 CRK25800.1 - 0.0022 18.6 0.0 2.7 8.7 0.0 2.9 2 1 0 2 2 2 2 Aspartyl protease DUF1180 PF06679.12 CRK25800.1 - 0.21 12.0 0.1 0.21 12.0 0.1 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF1180) GTP_EFTU PF00009.27 CRK25802.1 - 2.8e-58 196.7 0.2 7.5e-58 195.3 0.2 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 CRK25802.1 - 4.4e-32 110.0 0.0 9.2e-32 109.0 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 CRK25802.1 - 9.8e-31 106.0 0.0 2.2e-30 104.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 CRK25802.1 - 1.6e-22 79.4 0.0 3.5e-22 78.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 CRK25802.1 - 6.7e-14 52.0 0.0 1.5e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 CRK25802.1 - 1.9e-06 27.7 0.0 4.3e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain DUF148 PF02520.17 CRK25802.1 - 0.08 13.1 1.3 0.18 11.9 1.3 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF148 DUF442 PF04273.13 CRK25802.1 - 0.12 12.4 0.0 2.4 8.3 0.0 2.8 2 0 0 2 2 2 0 Putative phosphatase (DUF442) Iso_dh PF00180.20 CRK25803.1 - 1.6e-96 323.5 0.0 2.3e-96 323.0 0.0 1.2 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Ribosomal_S8 PF00410.19 CRK25805.1 - 1.9e-10 40.8 0.0 2.1e-09 37.4 0.0 2.1 1 1 0 1 1 1 1 Ribosomal protein S8 Aminotran_1_2 PF00155.21 CRK25807.1 - 1.7e-38 132.8 0.0 2.1e-38 132.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 CRK25807.1 - 6.3e-06 25.4 0.0 9.7e-06 24.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 CRK25807.1 - 1.4e-05 23.8 0.0 2e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_MocR PF12897.7 CRK25807.1 - 7.3e-05 21.7 0.0 0.00011 21.2 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase DegT_DnrJ_EryC1 PF01041.17 CRK25807.1 - 0.012 14.9 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family But2 PF09792.9 CRK25809.1 - 8.1e-57 191.6 0.5 8.1e-57 191.6 0.5 2.1 3 0 0 3 3 3 1 Ubiquitin 3 binding protein But2 C-terminal domain NGP1NT PF08153.12 CRK25810.1 - 9.5e-50 168.1 0.2 1.6e-49 167.4 0.2 1.4 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 CRK25810.1 - 1.2e-11 44.7 0.0 4e-08 33.3 0.0 2.7 2 1 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 CRK25810.1 - 0.00023 20.8 0.0 0.0072 15.9 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CRK25810.1 - 0.0015 18.5 0.0 0.0034 17.3 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase Arf PF00025.21 CRK25810.1 - 0.0077 15.7 0.0 0.3 10.5 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family AAA_16 PF13191.6 CRK25810.1 - 0.05 14.0 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 CRK25811.1 - 3.1e-16 60.1 0.0 5e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_18 PF13238.6 CRK25811.1 - 0.0023 18.5 0.0 0.0038 17.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 CRK25811.1 - 0.004 16.9 0.0 0.0095 15.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CRK25811.1 - 0.0062 16.5 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_33 PF13671.6 CRK25811.1 - 0.01 16.0 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 CRK25811.1 - 0.011 15.4 0.0 0.019 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CRK25811.1 - 0.013 15.9 0.0 0.023 15.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 CRK25811.1 - 0.017 15.1 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 CRK25811.1 - 0.018 14.7 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 CRK25811.1 - 0.1 12.9 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CRK25811.1 - 0.1 12.8 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 CRK25811.1 - 0.16 11.7 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system FtsK_SpoIIIE PF01580.18 CRK25811.1 - 0.18 11.2 0.0 0.33 10.3 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Pox_A32 PF04665.12 CRK25811.1 - 0.19 11.2 0.0 0.29 10.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein DUF4042 PF13251.6 CRK25813.1 - 0.0081 15.9 0.1 0.012 15.3 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4042) Phage_antiter_Q PF06323.11 CRK25813.1 - 0.018 14.6 0.1 0.021 14.4 0.1 1.1 1 0 0 1 1 1 0 Phage antitermination protein Q DrrA_P4M PF14860.6 CRK25813.1 - 0.025 14.4 0.5 0.037 13.9 0.3 1.4 1 1 0 1 1 1 0 DrrA phosphatidylinositol 4-phosphate binding domain Trep_Strep PF09605.10 CRK25813.1 - 0.032 14.2 0.0 0.04 13.9 0.0 1.1 1 0 0 1 1 1 0 Hypothetical bacterial integral membrane protein (Trep_Strep) APOC4 PF15119.6 CRK25813.1 - 0.036 14.3 0.1 0.049 13.9 0.1 1.3 1 0 0 1 1 1 0 Apolipoprotein C4 Dioxygenase_C PF00775.21 CRK25814.1 - 3.4e-10 39.7 0.1 5.4e-10 39.0 0.1 1.3 1 0 0 1 1 1 1 Dioxygenase Repressor_Mnt PF11423.8 CRK25818.1 - 0.047 13.5 0.0 0.13 12.0 0.0 1.8 1 0 0 1 1 1 0 Regulatory protein Mnt Pkinase PF00069.25 CRK25819.1 - 3.7e-10 39.6 0.2 4.8e-10 39.2 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK25819.1 - 3.7e-05 23.2 0.1 4.9e-05 22.7 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Chitin_synth_2 PF03142.15 CRK25820.1 - 7.2e-96 321.9 0.0 8.7e-96 321.6 0.0 1.0 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 CRK25820.1 - 3.1e-08 33.8 0.0 3.9e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 CRK25820.1 - 7.4e-05 22.7 0.0 0.00011 22.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 CRK25820.1 - 0.00021 20.8 0.0 0.00031 20.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 CRK25820.1 - 0.0025 17.7 0.0 0.004 17.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 UbiA PF01040.18 CRK25834.1 - 8e-21 74.5 0.4 8.6e-21 74.4 0.4 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family FtsJ PF01728.19 CRK25840.1 - 1.6e-11 44.7 0.0 2.3e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase GPI-anchored PF10342.9 CRK25841.1 - 0.0038 18.0 0.1 0.0052 17.5 0.1 1.3 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family FapA PF03961.13 CRK25842.1 - 0.015 13.9 4.4 0.02 13.5 4.4 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A EDR1 PF14381.6 CRK25842.1 - 0.049 13.3 1.0 0.061 13.0 1.0 1.3 1 0 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 DUF501 PF04417.12 CRK25842.1 - 0.09 12.6 1.7 0.16 11.8 1.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF501) DUF632 PF04782.12 CRK25842.1 - 0.096 12.0 7.5 0.12 11.6 7.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF632) Csm1_N PF18504.1 CRK25842.1 - 0.1 13.0 0.6 0.1 13.0 0.6 3.1 3 0 0 3 3 3 0 Csm1 N-terminal domain DUF2951 PF11166.8 CRK25842.1 - 0.13 12.5 6.6 0.049 13.9 2.7 2.3 2 1 0 3 3 3 0 Protein of unknown function (DUF2951) DUF4936 PF16290.5 CRK25842.1 - 0.29 11.9 1.6 0.56 10.9 0.3 2.2 2 1 1 3 3 2 0 Domain of unknown function (DUF4936) CREPT PF16566.5 CRK25842.1 - 0.34 11.1 9.2 0.32 11.1 1.4 2.3 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Gastrin PF00918.17 CRK25842.1 - 0.39 11.7 2.5 0.6 11.1 2.5 1.4 1 0 0 1 1 1 0 Gastrin/cholecystokinin family HBM PF16591.5 CRK25842.1 - 0.5 9.7 7.8 0.56 9.6 5.3 2.0 1 1 0 1 1 1 0 Helical bimodular sensor domain TcpS PF17456.2 CRK25842.1 - 0.53 10.3 5.3 0.87 9.6 1.9 2.1 1 1 1 2 2 2 0 Toxin-coregulated pilus protein S ABC_tran_CTD PF16326.5 CRK25842.1 - 0.64 10.3 15.8 11 6.4 0.7 3.5 2 1 1 3 3 3 0 ABC transporter C-terminal domain DivIC PF04977.15 CRK25842.1 - 0.72 9.7 13.6 0.96 9.3 1.2 3.1 2 1 0 3 3 3 0 Septum formation initiator DUF1664 PF07889.12 CRK25842.1 - 0.8 9.8 8.1 1.4 9.0 0.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DHR10 PF18595.1 CRK25842.1 - 1.4 9.0 18.6 8.6 6.5 8.5 2.7 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain DUF745 PF05335.13 CRK25842.1 - 1.5 8.5 9.8 0.67 9.7 6.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF745) KLRAQ PF10205.9 CRK25842.1 - 2.7 8.3 13.0 0.22 11.8 2.0 2.6 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein MFS_1 PF07690.16 CRK25843.1 - 3.7e-29 101.7 89.1 5.7e-24 84.7 55.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily HET PF06985.11 CRK25844.1 - 1.6e-11 44.7 0.4 2e-11 44.4 0.4 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_31 PF01055.26 CRK25845.1 - 4.2e-90 303.0 7.4 6.7e-90 302.4 7.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF4968 PF16338.5 CRK25845.1 - 4.5e-07 30.1 0.0 1e-06 28.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4968) zf-C2H2_4 PF13894.6 CRK25845.1 - 0.0049 17.6 16.4 0.4 11.7 0.0 4.4 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.26 CRK25845.1 - 0.85 10.2 13.7 1.8 9.1 0.1 3.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type TB2_DP1_HVA22 PF03134.19 CRK25846.1 - 1.4e-26 92.2 9.3 2.3e-26 91.5 9.3 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family CHCH PF06747.13 CRK25847.1 - 0.0095 16.0 4.7 0.027 14.6 4.7 1.8 1 1 0 1 1 1 1 CHCH domain OrfB_IS605 PF01385.19 CRK25847.1 - 0.15 12.2 0.0 0.2 11.9 0.0 1.1 1 0 0 1 1 1 0 Probable transposase CX9C PF16860.5 CRK25847.1 - 0.18 11.8 2.1 0.33 11.0 0.6 1.9 1 1 1 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, BPL_N PF09825.9 CRK25849.1 - 6.3e-140 466.5 0.0 7.9e-140 466.2 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 CRK25849.1 - 4.2e-18 65.5 0.0 6.6e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family ThuA PF06283.11 CRK25849.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Trehalose utilisation Pam16 PF03656.13 CRK25852.1 - 9.8e-31 106.4 0.1 1.3e-30 106.0 0.1 1.1 1 0 0 1 1 1 1 Pam16 Peptidase_S77 PF03420.13 CRK25852.1 - 0.094 12.4 0.0 0.23 11.1 0.0 1.6 1 1 0 2 2 2 0 Prohead core protein serine protease Beta_helix PF13229.6 CRK25853.1 - 6.1e-11 42.4 24.1 8.3e-09 35.5 15.5 3.2 1 1 2 3 3 3 3 Right handed beta helix region Chondroitinas_B PF14592.6 CRK25853.1 - 4.3e-07 29.2 0.4 2e-06 27.0 0.0 2.2 3 0 0 3 3 3 1 Chondroitinase B DUF1565 PF07602.11 CRK25853.1 - 0.014 14.7 0.1 0.014 14.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1565) Stig1 PF04885.13 CRK25854.1 - 6.2e-09 36.5 37.8 1.5e-05 25.5 14.2 9.7 1 1 10 12 12 12 2 Stigma-specific protein, Stig1 Yip1 PF04893.17 CRK25855.1 - 1.1e-06 28.4 23.0 0.0091 15.7 11.7 3.6 3 1 0 3 3 3 3 Yip1 domain CCB1 PF12046.8 CRK25855.1 - 0.2 11.0 0.6 20 4.5 0.1 2.3 2 0 0 2 2 2 0 Cofactor assembly of complex C subunit B RCC1 PF00415.18 CRK25856.1 - 2.9e-54 181.5 2.8 5.5e-12 46.1 0.0 7.8 7 2 1 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CRK25856.1 - 3.7e-38 128.6 19.3 9.5e-09 34.8 0.0 6.8 6 1 1 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Mg_trans_NIPA PF05653.14 CRK25858.1 - 1.5e-22 80.1 3.5 1.6e-22 80.0 3.5 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA eIF-3_zeta PF05091.12 CRK25860.1 - 5.1e-17 62.1 0.1 5.9e-17 61.8 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NUDIX PF00293.28 CRK25860.1 - 0.0054 16.8 0.4 0.0064 16.5 0.4 1.0 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 CRK25860.1 - 0.036 14.0 0.1 0.042 13.8 0.1 1.1 1 0 0 1 1 1 0 NUDIX domain DNA_pol_B_exo1 PF03104.19 CRK25864.1 - 1.9e-06 27.3 0.0 2.3e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain Snf7 PF03357.21 CRK25887.1 - 9.8e-17 61.1 16.7 9.8e-17 61.1 16.7 1.8 2 0 0 2 2 2 1 Snf7 AvrPto PF11592.8 CRK25887.1 - 0.0058 16.6 0.6 0.01 15.9 0.6 1.4 1 0 0 1 1 1 1 Central core of the bacterial effector protein AvrPto DUF775 PF05603.12 CRK25887.1 - 0.15 11.6 2.7 0.2 11.2 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF775) p450 PF00067.22 CRK25888.1 - 2.3e-35 122.2 0.1 2e-20 73.0 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 RE_HaeIII PF09556.10 CRK25888.1 - 0.01 15.0 0.1 2 7.5 0.0 2.2 2 0 0 2 2 2 0 HaeIII restriction endonuclease Enterotoxin_a PF01375.17 CRK25889.1 - 7.5e-16 58.5 0.0 1.1e-15 58.0 0.0 1.1 1 0 0 1 1 1 1 Heat-labile enterotoxin alpha chain SUR7 PF06687.12 CRK25889.1 - 1.4e-09 37.9 0.9 1.8e-09 37.5 0.1 1.5 2 0 0 2 2 2 1 SUR7/PalI family Sugar_tr PF00083.24 CRK25891.1 - 6.5e-117 391.1 22.5 7.6e-117 390.9 22.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK25891.1 - 4e-22 78.6 31.1 2.7e-20 72.6 21.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sulfatase PF00884.23 CRK25892.1 - 3e-65 220.7 0.1 4.5e-65 220.1 0.1 1.3 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 CRK25892.1 - 1.4e-20 73.4 6.3 1.5e-19 70.2 6.3 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4976) Phosphodiest PF01663.22 CRK25892.1 - 2e-06 27.7 6.8 8.1e-06 25.7 3.3 2.7 2 1 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 CRK25892.1 - 0.0041 15.8 0.1 0.011 14.4 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF229) Fungal_trans PF04082.18 CRK25893.1 - 8.9e-06 24.9 0.1 1.4e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_3 PF00933.21 CRK25894.1 - 9.2e-45 153.4 0.0 1.2e-44 152.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 CRK25894.1 - 1.1e-36 126.7 0.0 2.3e-36 125.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 CRK25894.1 - 2.5e-15 56.3 0.0 5.1e-15 55.3 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain GFO_IDH_MocA PF01408.22 CRK25895.1 - 6e-19 69.0 0.0 1.1e-18 68.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Zn_clus PF00172.18 CRK25896.1 - 0.00013 22.1 0.3 0.00013 22.1 0.3 3.3 3 0 0 3 3 3 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 CRK25896.1 - 0.00061 18.7 0.0 0.00089 18.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_4 PF01565.23 CRK25897.1 - 1.5e-09 37.7 0.2 2.8e-09 36.8 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 CRK25897.1 - 2.3e-05 24.4 0.0 4.9e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Glyco_hydro_61 PF03443.14 CRK25899.1 - 1.4e-47 162.3 0.1 1.7e-47 162.0 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Chitin_synth_2 PF03142.15 CRK25903.1 - 1.1e-42 146.4 0.0 1.2e-42 146.3 0.0 1.0 1 0 0 1 1 1 1 Chitin synthase Glycos_transf_2 PF00535.26 CRK25903.1 - 0.086 12.6 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 2 EST1_DNA_bind PF10373.9 CRK25934.1 - 4.7e-10 39.4 0.0 8.6e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain Defensin_propep PF00879.18 CRK25934.1 - 2.5 8.4 4.7 6.6 7.1 4.7 1.7 1 0 0 1 1 1 0 Defensin propeptide C166 PF17615.2 CRK25936.1 - 0.38 10.9 2.0 0.69 10.0 2.0 1.5 1 1 0 1 1 1 0 Family of unknown function RTC PF01137.21 CRK25938.1 - 1.3e-42 145.5 0.0 2.5e-42 144.6 0.0 1.5 1 1 0 1 1 1 1 RNA 3'-terminal phosphate cyclase LRR_8 PF13855.6 CRK25939.1 - 1.8e-06 27.6 1.0 5.3e-06 26.1 1.0 1.9 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 CRK25939.1 - 4.8e-05 23.6 0.1 0.00017 21.9 0.1 2.0 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CRK25939.1 - 0.057 14.0 2.8 7.1 7.6 0.4 3.6 3 0 0 3 3 3 0 Leucine Rich Repeat Ribosomal_S27e PF01667.17 CRK25940.1 - 6.2e-28 96.3 7.5 7.9e-28 95.9 7.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 TF_Zn_Ribbon PF08271.12 CRK25940.1 - 0.23 11.0 3.7 0.36 10.4 3.7 1.2 1 0 0 1 1 1 0 TFIIB zinc-binding NACHT PF05729.12 CRK25942.1 - 5.6e-06 26.4 0.0 1.3e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 CRK25942.1 - 0.051 14.0 0.0 0.082 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 CRK25942.1 - 0.062 13.6 0.0 0.1 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 CRK25942.1 - 0.14 11.9 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain FTA2 PF13095.6 CRK25943.1 - 1.4e-06 28.1 0.0 1.8e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Zn_clus PF00172.18 CRK25944.1 - 2e-10 40.6 11.5 2e-10 40.6 11.5 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L23eN PF03939.13 CRK25944.1 - 0.036 14.3 1.4 0.063 13.5 1.4 1.4 1 0 0 1 1 1 0 Ribosomal protein L23, N-terminal domain Clusterin PF01093.17 CRK25944.1 - 0.044 12.8 6.9 0.051 12.6 6.9 1.1 1 0 0 1 1 1 0 Clusterin Abhydrolase_6 PF12697.7 CRK25945.1 - 6.9e-05 23.6 1.8 0.00023 21.9 0.1 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CRK25945.1 - 0.00028 20.6 0.1 0.00048 19.9 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 CRK25945.1 - 0.0036 17.1 0.1 0.0065 16.2 0.1 1.4 1 0 0 1 1 1 1 PGAP1-like protein Ser_hydrolase PF06821.13 CRK25945.1 - 0.0044 16.9 0.1 0.0074 16.2 0.1 1.3 1 0 0 1 1 1 1 Serine hydrolase Hydrolase_4 PF12146.8 CRK25945.1 - 0.15 11.3 0.2 0.44 9.8 0.2 1.7 1 1 0 1 1 1 0 Serine aminopeptidase, S33 E1_UFD PF09358.10 CRK25946.1 - 0.14 12.8 0.2 0.37 11.5 0.1 1.7 2 0 0 2 2 2 0 Ubiquitin fold domain FtsX PF02687.21 CRK25946.1 - 0.31 11.5 4.8 1.8 9.1 3.5 2.6 2 1 0 2 2 2 0 FtsX-like permease family Pkinase PF00069.25 CRK25947.1 - 1.9e-32 112.7 0.0 2.1e-32 112.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK25947.1 - 1.6e-19 70.2 0.0 1.8e-19 70.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CRK25947.1 - 0.0014 18.0 0.0 0.0017 17.7 0.0 1.3 1 1 0 1 1 1 1 Kinase-like GGA_N-GAT PF18308.1 CRK25947.1 - 0.0038 16.8 0.0 0.0073 15.9 0.0 1.5 1 0 0 1 1 1 1 GGA N-GAT domain Kdo PF06293.14 CRK25947.1 - 0.008 15.6 0.0 0.011 15.1 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Cid2 PF09774.9 CRK25950.1 - 2.2e-48 164.7 0.0 2.9e-48 164.3 0.0 1.2 1 0 0 1 1 1 1 Caffeine-induced death protein 2 Sulfate_transp PF00916.20 CRK25952.1 - 1.6e-32 112.8 4.2 1.7e-32 112.6 4.2 1.0 1 0 0 1 1 1 1 Sulfate permease family Rab5ip PF07019.12 CRK25952.1 - 0.41 11.3 5.7 7.9 7.2 0.2 2.3 2 0 0 2 2 2 0 Rab5-interacting protein (Rab5ip) Complex1_51K PF01512.17 CRK25953.1 - 1.3e-38 132.2 0.0 2e-38 131.6 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 CRK25953.1 - 1.4e-17 63.6 0.2 2.7e-17 62.6 0.2 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 CRK25953.1 - 0.01 15.7 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 0 SLBB domain ABC2_membrane PF01061.24 CRK25980.1 - 8.8e-52 175.6 31.9 5.2e-29 101.2 9.1 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 CRK25980.1 - 4.1e-49 166.6 0.0 2.1e-23 83.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CRK25980.1 - 1.4e-11 44.8 12.7 0.0074 16.1 0.0 4.7 4 1 0 5 5 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 CRK25980.1 - 1.4e-08 35.1 0.0 0.024 14.9 0.0 3.5 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 CRK25980.1 - 2e-08 34.3 0.1 0.004 17.1 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 CRK25980.1 - 4.7e-08 33.8 1.5 0.0012 19.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 CRK25980.1 - 5.7e-08 32.4 3.7 0.0052 16.5 0.3 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 CRK25980.1 - 5.9e-08 33.3 1.7 0.0089 16.4 0.1 2.8 3 0 0 3 3 2 2 AAA ATPase domain SMC_N PF02463.19 CRK25980.1 - 7.1e-08 32.2 1.0 0.039 13.4 0.2 4.2 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 CRK25980.1 - 7.9e-06 26.2 0.2 0.034 14.4 0.1 2.6 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 CRK25980.1 - 2e-05 24.5 0.1 0.18 11.7 0.1 2.5 2 0 0 2 2 2 2 NACHT domain AAA_30 PF13604.6 CRK25980.1 - 2.7e-05 24.0 0.1 0.14 11.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 CRK25980.1 - 3e-05 24.4 0.1 0.045 14.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 CRK25980.1 - 7.2e-05 22.0 0.1 0.31 10.1 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein PDR_CDR PF06422.12 CRK25980.1 - 0.0001 22.2 0.0 0.00028 20.7 0.0 1.7 1 0 0 1 1 1 1 CDR ABC transporter AAA_25 PF13481.6 CRK25980.1 - 0.00012 21.7 1.1 0.26 10.9 0.0 2.9 3 0 0 3 3 3 2 AAA domain cobW PF02492.19 CRK25980.1 - 0.00036 20.2 1.3 0.72 9.4 0.0 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.6 CRK25980.1 - 0.00041 20.2 0.4 5.6 6.6 0.0 3.3 3 0 0 3 3 3 0 AAA ATPase domain AAA_24 PF13479.6 CRK25980.1 - 0.00057 19.7 0.0 0.48 10.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CRK25980.1 - 0.00061 20.2 0.1 1.9 8.9 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.6 CRK25980.1 - 0.00075 20.1 0.0 1.2 9.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 CRK25980.1 - 0.00078 19.0 0.1 0.31 10.5 0.1 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region MMR_HSR1 PF01926.23 CRK25980.1 - 0.0016 18.5 1.0 0.92 9.6 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 CRK25980.1 - 0.0032 16.9 1.6 0.48 9.7 0.3 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family ATP_bind_1 PF03029.17 CRK25980.1 - 0.0037 17.1 0.2 1 9.1 0.1 2.5 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_33 PF13671.6 CRK25980.1 - 0.0042 17.2 0.0 2.5 8.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 CRK25980.1 - 0.0046 16.4 0.3 1.8 8.0 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein Roc PF08477.13 CRK25980.1 - 0.0049 17.1 0.1 2.3 8.5 0.1 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA PF00004.29 CRK25980.1 - 0.0056 17.1 0.1 4.6 7.7 0.0 3.0 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 CRK25980.1 - 0.0069 16.3 0.0 1.8 8.4 0.0 2.3 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea Septin PF00735.18 CRK25980.1 - 0.0073 15.6 0.2 0.36 10.1 0.0 2.2 2 0 0 2 2 2 1 Septin SbcCD_C PF13558.6 CRK25980.1 - 0.0089 16.2 0.6 5.5 7.3 0.0 3.5 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.14 CRK25980.1 - 0.01 15.9 0.1 4.7 7.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.9 CRK25980.1 - 0.011 15.5 0.1 3.7 7.3 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MobB PF03205.14 CRK25980.1 - 0.012 15.6 0.1 1.7 8.6 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Pox_A32 PF04665.12 CRK25980.1 - 0.012 15.1 2.2 0.34 10.3 0.1 2.5 3 0 0 3 3 2 0 Poxvirus A32 protein Zeta_toxin PF06414.12 CRK25980.1 - 0.013 14.8 0.1 1.6 8.0 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin ABC_ATPase PF09818.9 CRK25980.1 - 0.019 13.8 0.7 2.3 6.9 0.3 3.0 3 0 0 3 3 3 0 Predicted ATPase of the ABC class IstB_IS21 PF01695.17 CRK25980.1 - 0.027 14.2 0.9 7 6.3 0.0 3.4 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_11 PF13086.6 CRK25980.1 - 0.03 14.1 4.3 1.2 8.8 0.0 2.9 3 0 0 3 3 3 0 AAA domain Sigma54_activat PF00158.26 CRK25980.1 - 0.048 13.4 0.1 12 5.6 0.0 3.2 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_17 PF13207.6 CRK25980.1 - 0.05 14.0 0.0 2 8.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 CRK25980.1 - 0.053 13.2 0.2 2.7 7.7 0.1 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family DUF2075 PF09848.9 CRK25980.1 - 0.056 12.7 0.2 3.7 6.7 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) G-alpha PF00503.20 CRK25980.1 - 0.069 12.3 0.0 9.8 5.2 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit SRPRB PF09439.10 CRK25980.1 - 0.069 12.6 0.2 6.3 6.2 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit SRP54 PF00448.22 CRK25980.1 - 0.082 12.5 0.1 9.8 5.7 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 CRK25980.1 - 0.1 12.5 0.1 11 5.8 0.0 3.3 4 0 0 4 4 4 0 NTPase Cytidylate_kin PF02224.18 CRK25980.1 - 0.12 12.1 0.2 6.4 6.4 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase PDR_assoc PF08370.11 CRK25980.1 - 0.78 9.5 3.4 0.6 9.9 0.4 2.4 2 0 0 2 2 2 0 Plant PDR ABC transporter associated UQ_con PF00179.26 CRK25982.1 - 8.8e-103 339.8 0.0 5.4e-50 168.7 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme SYS1 PF09801.9 CRK25982.1 - 1.8e-99 329.8 28.5 2.3e-44 151.1 2.6 5.7 7 0 0 7 7 4 4 Integral membrane protein S linking to the trans Golgi network NAD_binding_6 PF08030.12 CRK25982.1 - 4.8e-63 211.9 0.0 4.7e-30 104.8 0.0 2.5 2 0 0 2 2 2 2 Ferric reductase NAD binding domain Acyl-CoA_dh_1 PF00441.24 CRK25982.1 - 7.6e-45 152.8 2.8 6.8e-22 78.3 0.3 2.6 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain FAD_binding_8 PF08022.12 CRK25982.1 - 5.1e-41 139.2 0.0 5.9e-19 68.2 0.0 3.0 2 0 0 2 2 2 2 FAD-binding domain Acyl-CoA_dh_M PF02770.19 CRK25982.1 - 3.4e-33 113.7 0.0 3.9e-15 55.8 0.0 2.6 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, middle domain Ferric_reduct PF01794.19 CRK25982.1 - 1.6e-31 109.0 42.3 4.9e-18 65.5 11.6 3.9 2 2 1 3 3 3 2 Ferric reductase like transmembrane component Acyl-CoA_dh_N PF02771.16 CRK25982.1 - 4.6e-25 88.5 3.2 6e-18 65.5 0.4 3.1 3 0 0 3 3 3 2 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 CRK25982.1 - 1.2e-10 41.8 5.2 0.00017 21.9 0.5 2.4 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain Prok-E2_B PF14461.6 CRK25982.1 - 0.00011 21.9 0.0 0.72 9.6 0.0 2.4 2 0 0 2 2 2 2 Prokaryotic E2 family B RWD PF05773.22 CRK25982.1 - 0.00098 19.4 0.0 2.3 8.5 0.0 2.5 2 0 0 2 2 2 2 RWD domain NAD_binding_1 PF00175.21 CRK25982.1 - 0.026 15.2 0.0 21 5.8 0.0 3.1 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain Rsc14 PF08586.10 CRK25982.1 - 0.053 14.3 0.0 26 5.7 0.0 2.5 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit O-FucT PF10250.9 CRK25982.1 - 0.12 12.1 0.0 19 4.8 0.0 2.2 2 0 0 2 2 2 0 GDP-fucose protein O-fucosyltransferase DUF2845 PF11006.8 CRK25982.1 - 0.12 12.5 0.1 31 4.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2845) DUF4173 PF13777.6 CRK25982.1 - 0.2 11.1 14.8 1.3 8.4 4.3 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4173) Phage_holin_5_1 PF06946.11 CRK25982.1 - 0.6 10.5 5.3 5.7 7.4 0.6 2.8 2 0 0 2 2 2 0 Bacteriophage A118-like holin, Hol118 COX6B PF02297.17 CRK25990.1 - 8.9e-43 144.4 15.8 8.6e-23 80.4 4.9 2.2 2 0 0 2 2 2 2 Cytochrome oxidase c subunit VIb IL28A PF15177.6 CRK25990.1 - 1.7e-05 24.7 0.1 0.19 11.6 0.0 2.2 2 0 0 2 2 2 2 Interleukin-28A EKLF_TAD2 PF16833.5 CRK25990.1 - 0.00035 20.5 1.2 0.92 9.6 0.1 2.5 2 0 0 2 2 2 2 Erythroid krueppel-like transcription factor, transactivation 2 Pet191_N PF10203.9 CRK25990.1 - 0.0051 17.1 4.9 1.1 9.6 0.5 2.7 2 2 0 2 2 2 2 Cytochrome c oxidase assembly protein PET191 T4BSS_DotI_IcmL PF11393.8 CRK25990.1 - 0.0098 15.4 0.0 3.2 7.2 0.0 2.2 2 0 0 2 2 2 2 Type-IV b secretion system, inner-membrane complex component Aegerolysin PF06355.13 CRK25990.1 - 0.042 13.9 0.1 12 5.9 0.0 2.2 2 0 0 2 2 2 0 Aegerolysin dUTPase PF00692.19 CRK25990.1 - 0.054 13.2 0.1 5.7 6.6 0.0 2.1 2 0 0 2 2 2 0 dUTPase COX17 PF05051.13 CRK25990.1 - 0.074 13.4 5.7 41 4.6 0.2 4.0 4 0 0 4 4 4 0 Cytochrome C oxidase copper chaperone (COX17) RNA_bind PF08675.11 CRK25990.1 - 0.1 12.6 0.3 24 5.1 0.0 2.8 2 1 0 2 2 2 0 RNA binding domain DUF3425 PF11905.8 CRK25990.1 - 0.28 11.1 4.2 4.3 7.3 0.2 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3425) MRP-L47 PF06984.13 CRK25990.1 - 0.33 11.1 2.6 4.1 7.6 0.0 3.3 2 2 2 4 4 4 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) DUF3725 PF12523.8 CRK25990.1 - 1.1 9.6 6.3 13 6.1 0.2 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3725) PIP5K PF01504.18 CRK25993.1 - 1.4e-101 339.4 0.2 3e-101 338.2 0.2 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Lactamase_B_6 PF16661.5 CRK25993.1 - 9.5e-65 217.6 0.0 1.4e-64 217.1 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 CRK25993.1 - 2.1e-29 102.9 0.0 2.1e-29 102.9 0.0 3.7 4 0 0 4 4 4 1 Cleavage and polyadenylation factor 2 C-terminal RMMBL PF07521.12 CRK25993.1 - 1e-15 57.4 0.0 2.3e-15 56.3 0.0 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Beta-Casp PF10996.8 CRK25993.1 - 3.3e-15 56.3 0.0 1.1e-14 54.6 0.0 1.9 1 0 0 1 1 1 1 Beta-Casp domain Neur_chan_memb PF02932.16 CRK25993.1 - 1.7 8.7 3.8 1.5 8.8 0.8 2.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region PIP5K PF01504.18 CRK25994.1 - 2.7e-20 72.8 1.0 2.7e-20 72.8 1.0 1.6 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase Lactamase_B_6 PF16661.5 CRK25997.1 - 8.1e-65 217.9 0.0 1.2e-64 217.3 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 CRK25997.1 - 7.8e-50 169.4 0.0 7.8e-50 169.4 0.0 2.5 2 1 0 3 3 3 1 Cleavage and polyadenylation factor 2 C-terminal RMMBL PF07521.12 CRK25997.1 - 3.9e-16 58.7 0.0 1e-15 57.4 0.0 1.8 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Beta-Casp PF10996.8 CRK25997.1 - 4.3e-16 59.2 0.0 1.3e-15 57.7 0.0 1.8 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_2 PF12706.7 CRK25997.1 - 0.0018 17.8 0.0 0.043 13.3 0.0 2.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Sec23_trunk PF04811.15 CRK25999.1 - 5.6e-81 271.7 0.0 1.7e-47 162.0 0.0 4.6 4 2 1 5 5 5 3 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 CRK25999.1 - 2.1e-47 159.2 0.8 1.6e-22 79.2 0.1 2.5 2 0 0 2 2 2 2 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 CRK25999.1 - 4.8e-29 100.1 18.0 3.2e-14 52.7 5.0 2.7 2 0 0 2 2 2 2 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 CRK25999.1 - 4.4e-28 97.9 0.0 8.3e-17 61.7 0.0 2.7 2 0 0 2 2 2 2 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.22 CRK25999.1 - 1.2e-11 44.3 0.0 0.00027 20.8 0.0 2.7 2 0 0 2 2 2 2 Gelsolin repeat Vg_Tdu PF07545.14 CRK25999.1 - 0.00029 20.5 0.2 0.69 9.7 0.0 2.7 2 0 0 2 2 2 2 Vestigial/Tondu family Imm12 PF15560.6 CRK25999.1 - 0.016 15.2 0.0 6.6 6.7 0.0 2.6 2 0 0 2 2 2 0 Immunity protein 12 Vps36-NZF-N PF16988.5 CRK25999.1 - 0.12 11.8 0.2 23 4.5 0.0 2.5 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Phage_int_SAM_1 PF02899.17 CRK25999.1 - 0.4 11.0 2.3 72 3.8 0.0 3.7 4 0 0 4 4 4 0 Phage integrase, N-terminal SAM-like domain CYSTM PF12734.7 CRK25999.1 - 0.87 10.0 6.4 27 5.2 0.0 3.7 3 0 0 3 3 3 0 Cysteine-rich TM module stress tolerance DUF2263 PF10021.9 CRK26003.1 - 5.8e-11 43.0 0.0 9.5e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) CCDC24 PF15669.5 CRK26003.1 - 0.72 9.7 2.3 3.8 7.3 2.5 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family RSRP PF17069.5 CRK26003.1 - 1.4 8.5 14.2 2 7.9 14.2 1.2 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 RAP1 PF07218.11 CRK26003.1 - 6 5.0 9.9 7.9 4.6 9.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF3446 PF11928.8 CRK26003.1 - 6 7.2 15.3 20 5.6 11.4 2.4 2 0 0 2 2 2 0 Early growth response N-terminal domain tRNA-synt_2 PF00152.20 CRK26005.1 - 1.7e-65 221.2 0.0 3.5e-39 134.7 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class II (D, K and N) DASH_Duo1 PF08651.10 CRK26005.1 - 0.056 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 DASH complex subunit Duo1 tRNA-synt_2b PF00587.25 CRK26005.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) Fungal_trans_2 PF11951.8 CRK26009.1 - 6.8e-53 179.9 0.2 8.7e-53 179.5 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Amidase PF01425.21 CRK26009.1 - 7e-26 91.2 2.1 1.1e-24 87.2 2.2 2.1 2 0 0 2 2 2 1 Amidase CUE PF02845.16 CRK26013.1 - 7.6e-07 28.7 0.0 1.8e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 CUE domain FXMRP1_C_core PF12235.8 CRK26013.1 - 2.2 8.9 15.5 0.43 11.2 10.6 2.2 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal Ribosomal_S10 PF00338.22 CRK26015.1 - 1.7e-26 92.3 0.2 2.2e-26 91.9 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Fibrillarin_2 PF10113.9 CRK26015.1 - 0.0087 14.7 0.0 0.01 14.5 0.0 1.1 1 0 0 1 1 1 1 Fibrillarin-like archaeal protein Nucleoporin_FG PF13634.6 CRK26017.1 - 1.3e-06 29.1 146.6 0.097 13.5 24.4 7.0 2 2 5 7 7 7 5 Nucleoporin FG repeat region p450 PF00067.22 CRK26019.1 - 2.3e-41 142.0 0.0 3.5e-30 105.2 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Frag1 PF10277.9 CRK26021.1 - 3e-39 134.8 9.2 3e-39 134.8 9.2 3.0 2 1 1 3 3 3 1 Frag1/DRAM/Sfk1 family Exo_endo_phos PF03372.23 CRK26021.1 - 0.0064 16.0 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family U3_assoc_6 PF08640.11 CRK26022.1 - 1.6e-27 95.4 1.7 9.7e-26 89.7 0.2 2.5 1 1 1 2 2 2 2 U3 small nucleolar RNA-associated protein 6 NRDE-2 PF08424.10 CRK26022.1 - 4.6e-05 22.7 1.4 9e-05 21.7 1.4 1.4 1 0 0 1 1 1 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 CRK26022.1 - 0.078 13.8 1.4 45 5.2 0.1 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 CRK26022.1 - 0.28 11.4 3.2 4.5 7.5 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat EVE PF01878.18 CRK26024.1 - 5.6e-18 65.3 0.0 1.8e-17 63.7 0.0 1.7 2 0 0 2 2 2 1 EVE domain Basic PF01586.16 CRK26024.1 - 0.0088 17.2 0.1 0.017 16.3 0.1 1.5 1 0 0 1 1 1 1 Myogenic Basic domain ARID PF01388.21 CRK26025.1 - 1.8e-17 63.8 1.8 3e-17 63.1 0.0 2.4 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain Img2 PF05046.14 CRK26027.1 - 3.2e-20 72.2 0.0 5.3e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) fn3 PF00041.21 CRK26027.1 - 0.069 13.5 0.2 0.5 10.7 0.1 2.0 1 1 1 2 2 2 0 Fibronectin type III domain eIF3_N PF09440.10 CRK26029.1 - 9.9e-44 149.0 2.4 9.9e-44 149.0 2.4 1.9 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 CRK26029.1 - 3.2e-12 46.9 0.0 2.3e-11 44.1 0.0 2.4 2 0 0 2 2 2 1 PCI domain RPN7 PF10602.9 CRK26029.1 - 0.055 13.2 0.7 0.14 11.8 0.1 2.0 2 0 0 2 2 2 0 26S proteasome subunit RPN7 Caprin-1_dimer PF18293.1 CRK26029.1 - 0.084 13.4 1.4 0.2 12.2 0.1 2.3 3 0 0 3 3 3 0 Caprin-1 dimerization domain TPR_14 PF13428.6 CRK26029.1 - 0.72 10.8 2.7 30 5.8 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC1 PF12859.7 CRK26031.1 - 1.7e-41 141.8 0.3 5.8e-41 140.1 0.3 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 CRK26031.1 - 0.046 14.2 1.0 62 4.3 0.1 4.6 4 0 0 4 4 4 0 Proteasome/cyclosome repeat Clathrin PF00637.20 CRK26032.1 - 6.2e-21 74.8 7.3 2e-20 73.1 2.7 3.6 4 1 0 4 4 4 1 Region in Clathrin and VPS NBP1 PF08537.10 CRK26032.1 - 0.00064 19.2 1.1 0.0013 18.3 1.1 1.4 1 0 0 1 1 1 1 Fungal Nap binding protein NBP1 BUD22 PF09073.10 CRK26032.1 - 0.0013 18.2 7.8 0.0013 18.2 7.8 2.1 2 0 0 2 2 2 1 BUD22 DNA_pol_phi PF04931.13 CRK26032.1 - 0.028 12.5 28.9 0.046 11.8 28.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi Vps39_1 PF10366.9 CRK26032.1 - 0.034 14.4 0.2 0.14 12.4 0.2 2.1 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 Sigma70_ner PF04546.13 CRK26032.1 - 0.041 13.8 20.2 0.75 9.6 18.4 2.6 2 0 0 2 2 2 0 Sigma-70, non-essential region Mpp10 PF04006.12 CRK26032.1 - 0.073 11.5 17.8 0.14 10.6 17.8 1.3 1 0 0 1 1 1 0 Mpp10 protein WD40 PF00400.32 CRK26032.1 - 0.12 13.3 0.7 26 5.9 0.0 3.7 3 0 0 3 3 2 0 WD domain, G-beta repeat zf-RING_2 PF13639.6 CRK26032.1 - 0.25 11.7 2.9 3.5 8.0 0.4 2.4 2 0 0 2 2 2 0 Ring finger domain zf-RING_5 PF14634.6 CRK26032.1 - 0.29 11.1 2.1 0.97 9.5 2.1 1.9 1 1 0 1 1 1 0 zinc-RING finger domain zf-RING_11 PF17123.5 CRK26032.1 - 0.32 10.8 3.6 0.66 9.8 3.6 1.6 1 0 0 1 1 1 0 RING-like zinc finger DUF2722 PF10846.8 CRK26032.1 - 0.43 9.5 6.7 0.16 10.9 2.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) DUF913 PF06025.12 CRK26032.1 - 0.75 8.7 3.4 1.6 7.6 3.4 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Nop14 PF04147.12 CRK26032.1 - 2.1 6.4 29.2 4.2 5.5 29.2 1.4 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.15 CRK26032.1 - 2.5 6.8 5.9 4.6 5.9 5.9 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TRAP_alpha PF03896.16 CRK26032.1 - 2.5 7.2 12.8 5.1 6.2 12.8 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Vfa1 PF08432.10 CRK26032.1 - 5.1 7.4 11.5 14 5.9 11.5 1.7 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF4746 PF15928.5 CRK26032.1 - 6.5 6.1 12.1 14 5.0 12.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) PTPRCAP PF15713.5 CRK26032.1 - 8.6 6.6 23.8 11 6.2 19.4 2.8 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated RR_TM4-6 PF06459.12 CRK26032.1 - 8.8 6.1 9.1 20 4.9 9.1 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Lipase_GDSL_2 PF13472.6 CRK26034.1 - 8.6e-15 55.6 1.5 1.1e-14 55.2 1.5 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 CRK26034.1 - 0.063 13.2 0.0 0.086 12.8 0.0 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Pectinesterase PF01095.19 CRK26036.1 - 1.4e-50 171.7 7.8 1.7e-50 171.4 7.8 1.1 1 0 0 1 1 1 1 Pectinesterase Arf PF00025.21 CRK26041.1 - 2.5e-38 131.2 0.0 8.2e-25 87.2 0.0 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.20 CRK26041.1 - 2.7e-11 43.3 0.0 2.2e-06 27.1 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 CRK26041.1 - 3.2e-09 37.1 0.0 1.2e-08 35.2 0.0 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CRK26041.1 - 5.3e-09 35.9 0.0 0.00014 21.5 0.0 2.1 2 0 0 2 2 2 2 Ras family SRPRB PF09439.10 CRK26041.1 - 3.8e-06 26.5 0.0 7.5e-05 22.2 0.0 2.0 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CRK26041.1 - 3.9e-06 26.4 0.0 4.6e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CRK26041.1 - 0.0002 21.0 0.0 0.00098 18.7 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CRK26041.1 - 0.014 15.5 0.0 0.025 14.7 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase RNase_PH PF01138.21 CRK26043.1 - 2.2e-23 83.2 0.0 3.6e-23 82.5 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CRK26043.1 - 1.9e-08 34.2 0.0 3.4e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Cwf_Cwc_15 PF04889.12 CRK26045.1 - 5.2e-89 298.2 10.7 6e-89 298.0 10.7 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.12 CRK26045.1 - 0.0068 15.9 15.0 0.0081 15.6 15.0 1.1 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 CRK26045.1 - 0.016 13.5 13.2 0.016 13.5 13.2 1.1 1 0 0 1 1 1 0 Nop14-like family SAPS PF04499.15 CRK26045.1 - 0.75 8.5 4.3 0.74 8.5 4.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF3381 PF11861.8 CRK26045.1 - 1.5 8.6 17.3 2.6 7.8 17.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Merozoite_SPAM PF07133.11 CRK26045.1 - 4.2 7.3 22.2 5.8 6.9 22.2 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) CDC45 PF02724.14 CRK26045.1 - 5 5.3 21.5 5.9 5.1 21.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop53 PF07767.11 CRK26045.1 - 5.2 6.3 20.7 7.7 5.8 20.7 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) SIR4_SID PF16991.5 CRK26045.1 - 7 6.7 6.8 10 6.1 6.8 1.3 1 0 0 1 1 1 0 Sir4 SID domain Casc1_N PF15927.5 CRK26045.1 - 9.9 5.8 20.2 0.081 12.6 12.2 1.6 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus Ras PF00071.22 CRK26047.1 - 3.6e-55 186.0 0.0 6.1e-55 185.2 0.0 1.4 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CRK26047.1 - 3.6e-33 114.3 0.0 8.5e-33 113.1 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase EthD PF07110.11 CRK26047.1 - 1.4e-19 71.0 0.2 5.2e-19 69.2 0.2 2.1 1 0 0 1 1 1 1 EthD domain Arf PF00025.21 CRK26047.1 - 4.7e-12 45.7 0.0 8.5e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CRK26047.1 - 0.0013 18.8 0.0 0.0027 17.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase zf-C3HC4_3 PF13920.6 CRK26047.1 - 0.0021 17.9 12.2 0.0034 17.2 12.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) GTP_EFTU PF00009.27 CRK26047.1 - 0.0062 16.1 0.0 0.013 15.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CRK26047.1 - 0.0085 15.5 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region F420_oxidored PF03807.17 CRK26047.1 - 0.0089 16.6 1.5 0.036 14.6 1.5 2.1 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent MmlI PF09448.10 CRK26047.1 - 0.024 15.1 0.0 0.049 14.1 0.0 1.5 1 0 0 1 1 1 0 Methylmuconolactone methyl-isomerase 3HCDH_N PF02737.18 CRK26047.1 - 0.033 14.1 0.9 0.078 12.9 0.9 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain zf-RING_6 PF14835.6 CRK26047.1 - 0.26 11.2 7.5 0.5 10.3 7.5 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Cwf_Cwc_15 PF04889.12 CRK26050.1 - 1.5e-38 133.0 7.2 1.5e-38 133.0 7.2 4.5 2 1 2 4 4 4 1 Cwf15/Cwc15 cell cycle control protein Ras PF00071.22 CRK26052.1 - 5.1e-45 153.0 0.0 5.7e-45 152.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CRK26052.1 - 6.9e-35 119.9 0.0 8e-35 119.7 0.0 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CRK26052.1 - 6.9e-14 51.7 0.0 8.1e-14 51.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CRK26052.1 - 2.8e-05 24.2 0.0 3.3e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CRK26052.1 - 0.00014 21.4 0.0 0.00015 21.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 CRK26052.1 - 0.00045 20.6 0.0 0.00051 20.5 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain GTP_EFTU PF00009.27 CRK26052.1 - 0.013 15.1 0.0 0.023 14.2 0.0 1.5 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CRK26052.1 - 0.059 13.3 0.0 0.67 9.8 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase Kri1_C PF12936.7 CRK26057.1 - 2.5e-30 104.5 0.1 2.5e-30 104.5 0.1 3.5 5 0 0 5 5 5 1 KRI1-like family C-terminal Kri1 PF05178.12 CRK26057.1 - 5.5e-08 33.3 4.9 5.5e-08 33.3 4.9 3.8 3 2 1 4 4 4 1 KRI1-like family Dsh_C PF12316.8 CRK26057.1 - 7.2 7.0 7.5 10 6.5 2.5 2.2 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal Fungal_trans PF04082.18 CRK26058.1 - 1e-27 96.9 0.0 1.7e-27 96.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK26058.1 - 2e-09 37.4 10.9 3.2e-09 36.8 10.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain VF530 PF09905.9 CRK26058.1 - 0.03 14.5 0.0 0.099 12.8 0.0 1.9 1 0 0 1 1 1 0 DNA-binding protein VF530 Kri1 PF05178.12 CRK26060.1 - 3.1e-28 98.4 15.9 3.1e-28 98.4 15.9 4.7 4 1 1 5 5 5 1 KRI1-like family Kri1_C PF12936.7 CRK26060.1 - 3.2e-18 65.7 0.0 3.2e-18 65.7 0.0 4.5 5 1 0 5 5 5 1 KRI1-like family C-terminal Fungal_trans PF04082.18 CRK26062.1 - 2.9e-28 98.6 0.0 4.7e-28 98.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK26062.1 - 2.1e-09 37.3 10.9 3.3e-09 36.7 10.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain VF530 PF09905.9 CRK26062.1 - 0.03 14.5 0.0 0.1 12.8 0.0 1.9 1 0 0 1 1 1 0 DNA-binding protein VF530 Peptidase_C50 PF03568.17 CRK26064.1 - 6.1e-247 819.1 0.0 2.7e-162 540.4 0.0 2.4 2 0 0 2 2 2 2 Peptidase family C50 CHAT PF12770.7 CRK26064.1 - 3.7e-06 26.6 0.9 0.0031 17.0 0.0 4.4 3 1 0 3 3 3 1 CHAT domain JAKMIP_CC3 PF16034.5 CRK26064.1 - 0.11 12.4 0.0 28 4.6 0.0 2.7 2 0 0 2 2 2 0 JAKMIP CC3 domain ZapB PF06005.12 CRK26064.1 - 0.3 11.6 2.1 36 4.9 0.2 3.1 2 0 0 2 2 2 0 Cell division protein ZapB TPR_19 PF14559.6 CRK26064.1 - 3 8.4 6.7 4.2 8.0 0.3 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF5321 PF17254.2 CRK26067.1 - 2e-59 199.6 0.2 2.4e-59 199.4 0.2 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5321) DUF3708 PF12501.8 CRK26067.1 - 0.11 12.2 0.1 0.17 11.6 0.1 1.2 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter FGGY_C PF02782.16 CRK26069.1 - 1e-25 90.7 0.0 2e-25 89.7 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 CRK26069.1 - 3.6e-17 62.8 0.0 7.5e-15 55.2 0.0 2.6 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain DUF2385 PF09539.10 CRK26069.1 - 0.11 13.0 0.1 0.55 10.8 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2385) Peptidase_M14 PF00246.24 CRK26070.1 - 1.5e-14 54.5 0.0 4e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 CRK26070.1 - 0.0061 15.7 0.0 0.013 14.6 0.0 1.5 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family Med2 PF11214.8 CRK26072.1 - 0.05 13.8 0.0 0.058 13.5 0.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 2 OPT PF03169.15 CRK26074.1 - 3.9e-86 290.0 44.8 4.5e-86 289.8 44.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein XAP5 PF04921.14 CRK26076.1 - 1.9e-89 299.8 0.0 5.7e-89 298.2 0.0 1.8 1 1 0 1 1 1 1 XAP5, circadian clock regulator DUF4604 PF15377.6 CRK26076.1 - 7.5e-06 26.5 4.7 1.7e-05 25.3 4.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) DUF1218 PF06749.12 CRK26078.1 - 0.066 13.7 0.1 0.1 13.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1218) DNA_ligase_A_M PF01068.21 CRK26078.1 - 0.095 12.3 0.1 0.15 11.7 0.1 1.2 1 0 0 1 1 1 0 ATP dependent DNA ligase domain PfkB PF00294.24 CRK26080.1 - 1.7e-45 155.7 0.5 2.6e-45 155.0 0.5 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Fungal_trans_2 PF11951.8 CRK26080.1 - 1.3e-10 40.7 0.0 1.6e-09 37.1 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK26082.1 - 4e-09 36.4 12.0 7e-09 35.7 12.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain A_deaminase PF00962.22 CRK26084.1 - 4.4e-21 75.6 0.0 6.3e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase PLDc PF00614.22 CRK26087.1 - 6.2e-14 51.5 1.5 3.7e-07 30.0 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 CRK26087.1 - 2.1e-12 47.1 0.0 3.6e-05 23.6 0.0 3.7 3 0 0 3 3 3 3 PLD-like domain F-box-like PF12937.7 CRK26087.1 - 0.00012 21.8 0.3 0.0003 20.6 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CRK26087.1 - 0.1 12.5 0.6 0.23 11.4 0.6 1.6 1 0 0 1 1 1 0 F-box domain GLTP PF08718.11 CRK26089.1 - 1e-41 142.7 0.0 3.3e-41 141.0 0.0 1.7 2 0 0 2 2 2 1 Glycolipid transfer protein (GLTP) PMI_typeI PF01238.21 CRK26091.1 - 1.4e-67 228.5 0.0 1.2e-66 225.4 0.0 2.0 1 1 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.19 CRK26091.1 - 0.00058 19.8 0.0 0.0087 16.0 0.0 2.4 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_2 PF07883.11 CRK26091.1 - 0.0016 18.1 0.2 0.31 10.8 0.2 2.6 2 0 0 2 2 2 2 Cupin domain Pec_lyase_C PF00544.19 CRK26093.1 - 5.6e-29 101.2 0.6 1.3e-28 100.0 0.6 1.6 1 0 0 1 1 1 1 Pectate lyase tRNA-synt_1b PF00579.25 CRK26093.1 - 1.5e-19 70.4 0.0 3.2e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Rib_5-P_isom_A PF06026.14 CRK26096.1 - 4.7e-43 146.8 0.0 7.1e-43 146.2 0.0 1.2 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) MFS_1 PF07690.16 CRK26098.1 - 8e-39 133.5 44.2 8e-39 133.5 44.2 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 CRK26098.1 - 2.2e-13 49.5 16.7 3.1e-13 49.1 16.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Molybdopterin PF00384.22 CRK26100.1 - 8.1e-60 203.0 0.0 2.7e-59 201.3 0.0 1.7 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 CRK26100.1 - 9.7e-27 93.2 0.0 2.4e-26 92.0 0.0 1.7 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Molybdop_Fe4S4 PF04879.16 CRK26100.1 - 1e-12 47.8 1.0 1.9e-12 47.0 0.4 1.8 2 0 0 2 2 2 1 Molybdopterin oxidoreductase Fe4S4 domain MoeA_N PF03453.17 CRK26102.1 - 9.7e-28 96.9 0.4 1.4e-27 96.4 0.4 1.2 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.24 CRK26102.1 - 5.3e-27 94.2 0.0 9.9e-27 93.4 0.0 1.5 1 0 0 1 1 1 1 Probable molybdopterin binding domain MFS_1 PF07690.16 CRK26104.1 - 7e-20 71.2 30.7 7e-20 71.2 30.7 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily GPR_Gpa2_C PF11970.8 CRK26104.1 - 0.13 12.3 0.6 0.42 10.7 0.2 2.0 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term DEAD PF00270.29 CRK26106.1 - 2.3e-43 148.0 0.0 4.5e-43 147.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase PPR_2 PF13041.6 CRK26106.1 - 7.5e-31 106.1 14.7 2.8e-07 30.6 0.0 13.1 9 5 7 16 16 16 6 PPR repeat family PPR_3 PF13812.6 CRK26106.1 - 2.8e-23 81.7 0.1 0.01 15.9 0.0 9.9 6 3 5 11 11 11 6 Pentatricopeptide repeat domain PPR PF01535.20 CRK26106.1 - 3.6e-19 67.6 24.4 0.0063 16.7 0.0 12.7 14 0 0 14 14 14 4 PPR repeat PPR_long PF17177.4 CRK26106.1 - 2.4e-15 56.5 16.2 3.7e-06 26.5 0.3 6.9 4 2 1 6 6 6 3 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 CRK26106.1 - 4.5e-15 55.1 0.0 2.3e-06 27.2 0.0 8.1 9 0 0 9 9 9 2 PPR repeat GHMP_kinases_N PF00288.26 CRK26106.1 - 2.8e-14 53.1 5.2 4e-14 52.6 3.6 2.2 2 0 0 2 2 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 CRK26106.1 - 7e-07 29.5 0.6 3.8e-06 27.2 0.6 2.3 1 0 0 1 1 1 1 GHMP kinases C terminal Helicase_C PF00271.31 CRK26106.1 - 3.3e-06 27.4 0.0 1.2e-05 25.6 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CRK26106.1 - 0.00048 20.2 0.0 0.0012 18.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit GPP34 PF05719.11 CRK26106.1 - 0.0038 17.3 0.0 0.0038 17.3 0.0 2.7 3 0 0 3 3 3 1 Golgi phosphoprotein 3 (GPP34) ATP13 PF12921.7 CRK26106.1 - 0.0041 17.0 0.1 0.53 10.2 0.0 3.6 4 0 0 4 4 4 1 Mitochondrial ATPase expression RPM2 PF08579.11 CRK26106.1 - 0.039 14.3 0.0 0.29 11.6 0.0 2.5 3 0 0 3 3 3 0 Mitochondrial ribonuclease P subunit (RPM2) TPR_12 PF13424.6 CRK26106.1 - 0.07 13.4 6.5 20 5.6 0.0 5.7 4 1 1 5 5 5 0 Tetratricopeptide repeat DEAD PF00270.29 CRK26110.1 - 1.3e-44 152.0 0.1 2.1e-44 151.4 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CRK26110.1 - 2.4e-18 66.5 0.0 7.1e-18 65.0 0.0 1.9 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CRK26110.1 - 3.1e-15 56.2 0.0 6.9e-15 55.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 CRK26110.1 - 0.00011 22.3 0.0 0.00023 21.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PPR_2 PF13041.6 CRK26112.1 - 5.2e-32 109.8 16.5 2.1e-07 31.0 0.0 13.6 9 5 7 16 16 16 6 PPR repeat family PPR_3 PF13812.6 CRK26112.1 - 3.8e-23 81.3 0.2 0.0077 16.3 0.0 10.4 6 5 5 11 11 11 5 Pentatricopeptide repeat domain PPR PF01535.20 CRK26112.1 - 1.4e-20 72.0 24.3 0.0047 17.1 0.0 13.2 14 0 0 14 14 14 5 PPR repeat PPR_1 PF12854.7 CRK26112.1 - 2.3e-16 59.2 0.3 1.7e-06 27.6 0.0 8.4 10 0 0 10 10 10 2 PPR repeat PPR_long PF17177.4 CRK26112.1 - 3.1e-16 59.4 15.7 8.7e-06 25.2 0.2 6.8 4 2 0 6 6 6 5 Pentacotripeptide-repeat region of PRORP GHMP_kinases_N PF00288.26 CRK26112.1 - 1.4e-14 54.0 5.1 2.9e-14 53.0 3.6 2.4 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 CRK26112.1 - 2e-08 34.5 0.4 9.2e-08 32.4 0.4 2.3 1 0 0 1 1 1 1 GHMP kinases C terminal GPP34 PF05719.11 CRK26112.1 - 0.0007 19.7 0.7 0.0023 18.0 0.1 2.2 2 0 0 2 2 2 1 Golgi phosphoprotein 3 (GPP34) ATP13 PF12921.7 CRK26112.1 - 0.0038 17.1 0.1 0.42 10.5 0.0 3.6 4 0 0 4 4 4 1 Mitochondrial ATPase expression RPM2 PF08579.11 CRK26112.1 - 0.021 15.3 0.0 0.13 12.7 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial ribonuclease P subunit (RPM2) SelB-wing_2 PF09106.11 CRK26112.1 - 0.12 12.5 0.6 5.3 7.3 0.0 4.0 5 0 0 5 5 5 0 Elongation factor SelB, winged helix Aldedh PF00171.22 CRK26116.1 - 6.3e-132 440.4 0.0 7e-132 440.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 CRK26116.1 - 4.9e-05 22.6 0.0 0.0001 21.5 0.0 1.5 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) Prefoldin_2 PF01920.20 CRK26116.1 - 0.25 11.3 1.0 18 5.3 0.4 2.4 2 0 0 2 2 2 0 Prefoldin subunit NMD3 PF04981.13 CRK26118.1 - 4.1e-74 249.1 2.3 6.1e-74 248.5 2.3 1.3 1 0 0 1 1 1 1 NMD3 family DUF35_N PF12172.8 CRK26118.1 - 0.07 13.0 3.9 0.45 10.4 0.2 3.1 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) CpXC PF14353.6 CRK26118.1 - 0.93 9.6 7.3 0.59 10.2 0.7 2.9 2 1 0 2 2 2 0 CpXC protein C1_1 PF00130.22 CRK26118.1 - 3.3 7.7 7.0 2.5 8.1 1.4 3.0 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DZR PF12773.7 CRK26118.1 - 5.6 7.1 8.7 26 5.0 5.4 2.8 2 1 0 2 2 2 0 Double zinc ribbon Tnp_zf-ribbon_2 PF13842.6 CRK26118.1 - 8.6 7.3 8.3 32 5.4 3.7 3.4 1 1 1 2 2 2 0 DDE_Tnp_1-like zinc-ribbon TAL_FSA PF00923.19 CRK26120.1 - 8e-42 143.5 0.0 9.6e-42 143.3 0.0 1.1 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Ank_2 PF12796.7 CRK26122.1 - 1.4e-64 214.7 2.4 2.7e-10 40.7 0.1 10.0 3 2 8 11 11 11 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CRK26122.1 - 9.5e-50 166.4 11.5 2.1e-05 25.0 0.1 12.3 4 3 10 14 14 14 10 Ankyrin repeats (many copies) Ank_5 PF13857.6 CRK26122.1 - 2.8e-46 154.9 25.0 4.7e-07 30.0 0.1 14.1 8 3 6 14 14 14 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 CRK26122.1 - 4.6e-38 124.9 20.7 0.014 15.9 0.1 17.5 18 1 0 18 18 16 8 Ankyrin repeat Ank PF00023.30 CRK26122.1 - 3.8e-29 99.8 29.8 0.028 14.9 0.0 15.1 16 0 0 16 16 15 7 Ankyrin repeat NACHT PF05729.12 CRK26122.1 - 1.1e-08 35.2 0.0 3.9e-08 33.4 0.0 2.0 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 CRK26122.1 - 0.001 19.3 0.0 0.0031 17.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 CRK26122.1 - 0.002 17.8 0.0 0.013 15.2 0.0 2.0 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_19 PF13245.6 CRK26122.1 - 0.0068 16.7 0.2 0.045 14.1 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CRK26122.1 - 0.011 16.1 0.0 0.03 14.7 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain PIF1 PF05970.14 CRK26122.1 - 0.016 14.4 0.0 0.026 13.7 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase DUF2075 PF09848.9 CRK26122.1 - 0.032 13.5 0.0 0.053 12.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.17 CRK26122.1 - 0.063 13.0 0.1 0.34 10.6 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein PhoH PF02562.16 CRK26122.1 - 0.068 12.6 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein TsaE PF02367.17 CRK26122.1 - 0.071 13.1 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ResIII PF04851.15 CRK26122.1 - 0.085 12.9 0.0 0.39 10.7 0.0 2.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit NB-ARC PF00931.22 CRK26122.1 - 0.089 12.0 0.1 0.31 10.2 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain AAA_7 PF12775.7 CRK26122.1 - 0.097 12.2 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Myosin_head PF00063.21 CRK26122.1 - 0.098 10.9 0.0 0.15 10.2 0.0 1.1 1 0 0 1 1 1 0 Myosin head (motor domain) AAA_10 PF12846.7 CRK26122.1 - 0.13 11.2 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain DUF87 PF01935.17 CRK26122.1 - 0.15 12.1 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain RNA_helicase PF00910.22 CRK26122.1 - 0.15 12.4 0.0 0.37 11.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA PF00004.29 CRK26122.1 - 0.16 12.4 0.0 0.36 11.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Torsin PF06309.11 CRK26122.1 - 0.17 12.0 0.0 0.4 10.8 0.0 1.5 1 0 0 1 1 1 0 Torsin Mpv17_PMP22 PF04117.12 CRK26126.1 - 1.2e-17 63.9 0.4 2.8e-17 62.7 0.4 1.7 1 0 0 1 1 1 1 Mpv17 / PMP22 family DUF2530 PF10745.9 CRK26126.1 - 0.6 10.4 5.5 0.24 11.6 1.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2530) BNR_2 PF13088.6 CRK26129.1 - 9.6e-08 31.7 0.6 0.0028 17.0 0.1 2.4 2 1 0 2 2 2 2 BNR repeat-like domain CoA_transf_3 PF02515.17 CRK26130.1 - 1.8e-104 349.8 0.1 2.4e-104 349.4 0.1 1.1 1 0 0 1 1 1 1 CoA-transferase family III Acetyltransf_2 PF00797.17 CRK26130.1 - 6.9e-37 127.5 0.0 1e-36 127.0 0.0 1.2 1 0 0 1 1 1 1 N-acetyltransferase HRI1 PF16815.5 CRK26132.1 - 3.8e-72 242.7 1.8 4.3e-72 242.5 1.8 1.0 1 0 0 1 1 1 1 Protein HRI1 DUF3370 PF11850.8 CRK26132.1 - 0.24 10.3 0.1 0.47 9.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3370) Linker_histone PF00538.19 CRK26133.1 - 2.7e-24 85.3 0.0 2.7e-24 85.3 0.0 2.0 2 0 0 2 2 2 1 linker histone H1 and H5 family RR_TM4-6 PF06459.12 CRK26133.1 - 1.1 9.1 27.5 0.069 13.0 21.5 1.7 1 1 1 2 2 2 0 Ryanodine Receptor TM 4-6 SAPS PF04499.15 CRK26133.1 - 5.5 5.7 8.4 5.9 5.6 8.4 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Hamartin PF04388.12 CRK26133.1 - 5.7 5.5 14.4 6.8 5.2 14.4 1.1 1 0 0 1 1 1 0 Hamartin protein Asp-B-Hydro_N PF05279.11 CRK26133.1 - 5.7 6.9 16.4 7 6.6 16.4 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Hid1 PF12722.7 CRK26133.1 - 6 4.9 10.0 6 4.9 10.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF829 PF05705.14 CRK26136.1 - 8.7e-45 153.5 0.0 1.1e-44 153.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) DLH PF01738.18 CRK26136.1 - 0.18 11.3 0.9 0.5 9.9 0.1 2.0 2 2 0 2 2 2 0 Dienelactone hydrolase family zf-CCHC PF00098.23 CRK26137.1 - 0.79 9.9 8.1 0.14 12.2 3.3 2.1 2 0 0 2 2 2 0 Zinc knuckle Evr1_Alr PF04777.13 CRK26138.1 - 2.8e-26 91.9 0.0 7.6e-26 90.5 0.0 1.7 1 0 0 1 1 1 1 Erv1 / Alr family TPP_enzyme_M PF00205.22 CRK26138.1 - 2.2e-22 79.3 0.0 3.7e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_N PF02776.18 CRK26138.1 - 3.1e-21 75.7 0.2 6e-21 74.8 0.2 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 CRK26138.1 - 1.2e-13 51.1 0.0 2.4e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 CRK26138.1 - 0.055 12.4 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component CotE PF10628.9 CRK26138.1 - 0.11 12.2 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Outer spore coat protein E (CotE) DXP_synthase_N PF13292.6 CRK26138.1 - 0.11 11.7 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase HEM4 PF02602.15 CRK26141.1 - 4.3e-38 131.0 0.0 6e-38 130.5 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Whi5 PF08528.11 CRK26143.1 - 5.2e-09 35.5 0.1 1.2e-08 34.3 0.1 1.7 1 0 0 1 1 1 1 Whi5 like Metallopep PF12044.8 CRK26144.1 - 6.7e-129 430.2 0.0 8.7e-129 429.9 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.17 CRK26144.1 - 1.7e-07 31.2 0.0 3.2e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Jacalin-like lectin domain ISET-FN3_linker PF16625.5 CRK26144.1 - 2.7 8.6 16.7 10 6.7 4.4 2.8 2 0 0 2 2 2 0 Unstructured linking region I-set and fnIII on Brother of CDO CDP-OH_P_transf PF01066.21 CRK26146.1 - 1.3e-13 51.5 0.9 3.8e-13 50.0 0.9 1.8 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase tRNA-synt_2b PF00587.25 CRK26148.1 - 6.9e-31 107.6 0.0 9.7e-29 100.6 0.0 3.2 3 0 0 3 3 3 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_SAD PF07973.14 CRK26148.1 - 3.8e-24 84.5 0.0 1.7e-10 40.9 0.0 2.8 2 0 0 2 2 2 2 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 CRK26148.1 - 3.9e-24 84.5 0.0 1.4e-10 41.0 0.0 2.5 2 0 0 2 2 2 2 TGS domain HGTP_anticodon PF03129.20 CRK26148.1 - 1.5e-20 73.1 0.2 3.4e-20 72.0 0.2 1.6 1 0 0 1 1 1 1 Anticodon binding domain DUF4256 PF14066.6 CRK26148.1 - 0.019 14.7 0.0 9.3 5.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4256) Clr2_transil PF16761.5 CRK26148.1 - 0.021 15.6 0.2 17 6.3 0.0 2.6 2 0 0 2 2 2 0 Transcription-silencing protein, cryptic loci regulator Clr2 DUF1923 PF09083.10 CRK26148.1 - 0.22 11.2 1.8 23 4.8 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1923) Gar1 PF04410.14 CRK26151.1 - 5e-39 133.6 0.0 6.1e-39 133.3 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region Gar1 PF04410.14 CRK26153.1 - 2.6e-59 199.4 0.0 2.5e-38 131.3 0.0 2.0 2 0 0 2 2 2 2 Gar1/Naf1 RNA binding region PH PF00169.29 CRK26155.1 - 0.0006 20.3 0.0 0.0016 18.9 0.0 1.8 1 0 0 1 1 1 1 PH domain DUF5344 PF17279.2 CRK26155.1 - 0.013 16.0 0.2 0.92 10.1 0.1 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5344) Prominin PF05478.11 CRK26155.1 - 0.053 11.5 0.3 0.08 10.9 0.3 1.1 1 0 0 1 1 1 0 Prominin LCAT PF02450.15 CRK26157.1 - 1.7e-98 330.4 0.0 3.4e-98 329.4 0.0 1.4 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 CRK26157.1 - 0.0013 19.4 0.7 0.0037 17.9 0.1 2.0 1 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CRK26157.1 - 0.032 13.5 0.0 0.075 12.3 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Acetyltransf_1 PF00583.25 CRK26160.1 - 5.8e-19 68.5 0.0 1.2e-18 67.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CRK26160.1 - 2e-11 43.9 0.0 6.2e-11 42.3 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CRK26160.1 - 4e-10 40.0 0.0 9e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CRK26160.1 - 4.5e-09 36.2 0.0 1.2e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 CRK26160.1 - 3e-06 27.9 0.0 9e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CRK26160.1 - 3.8e-05 23.8 0.0 0.0001 22.4 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 CRK26160.1 - 0.00014 21.5 0.0 0.00034 20.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Xpo1 PF08389.12 CRK26160.1 - 0.00055 20.0 0.1 0.0051 16.9 0.0 2.7 2 0 0 2 2 2 1 Exportin 1-like protein Acetyltransf_CG PF14542.6 CRK26160.1 - 0.027 14.6 0.1 0.064 13.4 0.1 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Fungal_trans_2 PF11951.8 CRK26163.1 - 9.3e-05 21.4 0.1 0.00017 20.5 0.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Beta_protein PF14350.6 CRK26163.1 - 0.13 11.6 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Beta protein Glyco_hydro_88 PF07470.13 CRK26171.1 - 1.8e-09 37.2 0.5 2.2e-09 36.9 0.5 1.1 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_hydro_127 PF07944.12 CRK26171.1 - 0.0057 15.2 0.0 0.0057 15.2 0.0 1.1 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 C5-epim_C PF06662.13 CRK26171.1 - 0.0095 15.5 0.1 0.02 14.4 0.1 1.7 1 1 0 1 1 1 1 D-glucuronyl C5-epimerase C-terminus ICL PF00463.21 CRK26174.1 - 5.3e-53 180.3 0.1 5.9e-53 180.2 0.1 1.0 1 0 0 1 1 1 1 Isocitrate lyase family LPD14 PF18827.1 CRK26174.1 - 0.064 13.5 0.0 0.074 13.3 0.0 1.1 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 14 Iso_dh PF00180.20 CRK26179.1 - 6.2e-96 321.6 0.0 8.8e-96 321.1 0.0 1.2 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase GTP_EFTU PF00009.27 CRK26180.1 - 1.9e-58 197.2 0.1 5e-58 195.9 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 CRK26180.1 - 4.3e-32 110.0 0.0 9.2e-32 109.0 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 CRK26180.1 - 9.8e-31 106.0 0.0 2.2e-30 104.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 CRK26180.1 - 1.6e-22 79.4 0.0 3.5e-22 78.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 CRK26180.1 - 6.6e-14 52.1 0.0 1.5e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 CRK26180.1 - 1.9e-06 27.7 0.0 4.3e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain DUF148 PF02520.17 CRK26180.1 - 0.08 13.1 1.3 0.18 11.9 1.3 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF148 DUF442 PF04273.13 CRK26180.1 - 0.12 12.5 0.0 2.4 8.3 0.0 2.9 2 0 0 2 2 2 0 Putative phosphatase (DUF442) Asp PF00026.23 CRK26182.1 - 6.4e-58 196.6 0.0 3.1e-57 194.4 0.0 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CRK26182.1 - 1.1e-08 35.6 0.2 5.3e-07 30.0 0.2 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 CRK26182.1 - 0.0063 17.1 0.0 5.1 7.8 0.0 2.8 2 1 0 2 2 2 2 Aspartyl protease DUF3328 PF11807.8 CRK26183.1 - 1.6e-22 80.4 0.1 2.5e-22 79.8 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) PBP1_TM PF14812.6 CRK26183.1 - 0.2 12.0 0.9 3 8.3 0.3 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Methyltransf_22 PF13383.6 CRK26184.1 - 7.9e-18 64.9 0.0 1.2e-17 64.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 CRK26184.1 - 2.7e-07 30.8 0.0 4e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain Flavodoxin_2 PF02525.17 CRK26184.1 - 8.4e-06 25.6 0.0 1.7e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 CRK26184.1 - 1.8e-05 24.6 0.0 3.3e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.25 CRK26184.1 - 0.024 14.9 0.1 0.32 11.2 0.1 2.3 1 1 0 1 1 1 0 Flavodoxin BTRD1 PF17660.1 CRK26184.1 - 0.032 14.0 0.0 0.081 12.7 0.0 1.6 1 0 0 1 1 1 0 Bacterial tandem repeat domain 1 Flavodoxin_5 PF12724.7 CRK26184.1 - 0.15 12.3 0.0 4.1 7.6 0.0 2.7 2 1 1 3 3 3 0 Flavodoxin domain DUF4267 PF14087.6 CRK26186.1 - 8.7e-10 38.7 2.8 8.7e-10 38.7 2.8 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4267) 30K_MP_core PF17644.1 CRK26186.1 - 0.05 13.5 0.0 5.3 6.9 0.0 2.4 2 0 0 2 2 2 0 Core domain of 30K viral movement proteins Epimerase PF01370.21 CRK26187.1 - 0.067 12.6 0.0 0.16 11.4 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Epimerase PF01370.21 CRK26188.1 - 1.1e-08 34.9 0.1 8e-08 32.0 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 CRK26188.1 - 6.6e-05 22.6 0.1 0.0058 16.2 0.2 2.1 2 0 0 2 2 2 2 NmrA-like family GDP_Man_Dehyd PF16363.5 CRK26188.1 - 0.0017 17.8 0.1 0.0035 16.8 0.0 1.5 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase SET PF00856.28 CRK26189.1 - 1.1e-08 35.7 0.0 5.8e-08 33.3 0.0 2.1 1 1 0 1 1 1 1 SET domain Fungal_trans PF04082.18 CRK26190.1 - 6.3e-08 32.0 0.2 9.6e-08 31.4 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK26190.1 - 1.5e-05 25.0 7.1 2.4e-05 24.3 7.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Arginase PF00491.21 CRK26191.1 - 1.6e-78 264.1 0.9 2e-78 263.7 0.9 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 CRK26191.1 - 0.17 12.1 0.5 0.27 11.4 0.5 1.3 1 0 0 1 1 1 0 UPF0489 domain WD40 PF00400.32 CRK26192.1 - 1.3e-29 101.8 6.5 1.7e-05 25.5 0.0 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK26192.1 - 1.7e-12 47.5 0.3 4.1e-05 23.8 0.1 3.9 2 2 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CRK26192.1 - 0.0085 14.8 0.6 0.56 8.8 0.3 2.6 1 1 1 2 2 2 1 Nucleoporin Nup120/160 eIF2A PF08662.11 CRK26192.1 - 0.0088 15.9 0.5 3.4 7.5 0.0 3.1 2 1 2 4 4 4 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CRK26192.1 - 0.021 13.8 3.6 3.2 6.6 0.0 3.6 2 2 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Peptidase_M24 PF00557.24 CRK26193.1 - 1.9e-46 158.4 0.0 2.5e-46 158.0 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 CRK26193.1 - 1.9e-21 76.1 8.0 3.6e-21 75.2 8.0 1.5 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 CRK26193.1 - 0.00049 20.1 4.9 0.00049 20.1 4.9 2.2 2 0 0 2 2 2 1 MYND finger FAD_binding_3 PF01494.19 CRK26194.1 - 8.4e-18 64.7 0.0 1.9e-17 63.6 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 CRK26194.1 - 2.1e-05 24.7 0.0 6.3e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CRK26194.1 - 2.7e-05 23.6 0.0 9.2e-05 21.8 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CRK26194.1 - 0.0032 17.1 0.0 0.0066 16.1 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 CRK26194.1 - 0.0048 17.4 0.0 0.028 15.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CRK26194.1 - 0.0055 15.5 0.0 0.0086 14.8 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 CRK26194.1 - 0.0067 15.6 0.0 0.014 14.5 0.0 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 CRK26194.1 - 0.013 14.8 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain SE PF08491.10 CRK26194.1 - 0.015 14.4 0.0 0.038 13.0 0.0 1.6 2 0 0 2 2 2 0 Squalene epoxidase FAD_oxidored PF12831.7 CRK26194.1 - 0.023 14.0 0.1 0.06 12.7 0.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 CRK26194.1 - 0.052 13.4 0.0 0.13 12.1 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain zf-MYND PF01753.18 CRK26195.1 - 2.2e-09 37.3 12.6 4.1e-09 36.4 12.6 1.4 1 0 0 1 1 1 1 MYND finger Thi4 PF01946.17 CRK26197.1 - 1.7e-113 377.6 0.1 2.2e-113 377.3 0.1 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 CRK26197.1 - 2.3e-08 34.0 3.3 3.2e-07 30.3 1.4 2.1 1 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CRK26197.1 - 4.2e-06 26.1 2.8 0.00021 20.5 0.6 2.6 2 1 1 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.6 CRK26197.1 - 8.1e-06 26.0 1.3 2.2e-05 24.6 0.5 2.2 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 CRK26197.1 - 2.7e-05 23.4 0.4 3.4e-05 23.1 0.4 1.4 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 CRK26197.1 - 6.1e-05 22.4 0.0 7.9e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CRK26197.1 - 0.00018 21.5 0.0 0.00041 20.4 0.0 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 CRK26197.1 - 0.0039 16.6 0.4 0.0054 16.1 0.4 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 CRK26197.1 - 0.012 14.9 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CRK26197.1 - 0.024 13.3 0.7 0.035 12.8 0.7 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 CRK26197.1 - 0.025 13.8 0.0 0.036 13.3 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 CRK26197.1 - 0.074 12.1 0.2 0.19 10.8 0.2 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 CRK26197.1 - 0.11 11.3 0.3 0.16 10.8 0.3 1.1 1 0 0 1 1 1 0 Tryptophan halogenase K_oxygenase PF13434.6 CRK26197.1 - 0.22 10.6 0.0 0.33 10.0 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) adh_short PF00106.25 CRK26198.1 - 5.1e-18 65.2 0.0 7.5e-13 48.4 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CRK26198.1 - 5.1e-07 29.5 0.0 3e-06 27.0 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK26198.1 - 8.4e-07 29.1 0.5 1.4e-06 28.3 0.5 1.3 1 0 0 1 1 1 1 KR domain Rab_bind PF16704.5 CRK26198.1 - 0.059 13.4 0.2 3.8 7.6 0.1 2.3 2 0 0 2 2 2 0 Rab binding domain AICARFT_IMPCHas PF01808.18 CRK26199.1 - 5.7e-11 42.4 0.0 6.5e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme RasGEF PF00617.19 CRK26200.1 - 2.1e-26 93.2 3.2 2.3e-26 93.1 3.2 1.0 1 0 0 1 1 1 1 RasGEF domain Ribos_L4_asso_C PF14374.6 CRK26205.1 - 4.3e-29 100.4 1.6 4.9e-29 100.2 1.6 1.0 1 0 0 1 1 1 1 60S ribosomal protein L4 C-terminal domain Asp_protease PF09668.10 CRK26220.1 - 8.8e-35 119.2 0.2 1.1e-34 118.9 0.2 1.1 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CRK26220.1 - 1.1e-11 45.1 0.0 1.6e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.11 CRK26220.1 - 0.00013 21.7 0.0 0.00017 21.4 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease DUF3577 PF12101.8 CRK26220.1 - 0.039 13.7 0.1 0.053 13.3 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3577) Asp_protease_2 PF13650.6 CRK26220.1 - 0.052 14.2 0.0 0.067 13.8 0.0 1.2 1 0 0 1 1 1 0 Aspartyl protease GTP_CH_N PF12471.8 CRK26223.1 - 1.3e-83 279.5 0.0 2.1e-83 278.9 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal Ribosomal_S3Ae PF01015.18 CRK26223.1 - 9.1e-60 201.7 0.3 1.4e-59 201.1 0.3 1.2 1 0 0 1 1 1 1 Ribosomal S3Ae family GTP_cyclohydro2 PF00925.20 CRK26223.1 - 3.3e-16 59.3 0.0 5.9e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 GTP cyclohydrolase II SUI1 PF01253.22 CRK26223.1 - 0.15 12.6 0.0 0.34 11.5 0.0 1.5 1 0 0 1 1 1 0 Translation initiation factor SUI1 UPRTase PF14681.6 CRK26224.1 - 3.1e-64 216.2 0.0 2.8e-59 200.0 0.0 2.1 1 1 1 2 2 2 2 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 CRK26224.1 - 0.0091 15.5 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.13 CRK26224.1 - 0.04 13.9 0.1 0.062 13.3 0.1 1.2 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) WAPL PF07814.13 CRK26225.1 - 5.2e-45 153.8 0.5 9.5e-45 153.0 0.5 1.4 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin DUF383 PF04063.14 CRK26225.1 - 0.18 11.4 0.5 0.7 9.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF383) Peptidase_C78 PF07910.13 CRK26226.1 - 3.7e-33 114.8 0.2 5.2e-33 114.3 0.2 1.1 1 0 0 1 1 1 1 Peptidase family C78 Hist_deacetyl PF00850.19 CRK26226.1 - 0.096 12.1 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Histone deacetylase domain Apyrase PF06079.11 CRK26226.1 - 0.19 10.9 0.0 0.26 10.4 0.0 1.1 1 0 0 1 1 1 0 Apyrase Myosin_head PF00063.21 CRK26227.1 - 2.3e-245 816.0 0.6 5.8e-245 814.6 0.2 1.8 2 0 0 2 2 2 1 Myosin head (motor domain) Ham1p_like PF01725.16 CRK26227.1 - 1.3e-54 185.0 0.0 6.4e-54 182.7 0.0 2.3 2 0 0 2 2 1 1 Ham1 family AAA_18 PF13238.6 CRK26227.1 - 7.7e-31 107.3 0.2 2.9e-28 99.0 0.0 3.9 3 0 0 3 3 3 1 AAA domain DIL PF01843.19 CRK26227.1 - 2.9e-26 91.8 2.7 2.9e-26 91.8 2.7 2.8 2 0 0 2 2 1 1 DIL domain IQ PF00612.27 CRK26227.1 - 2e-13 48.8 43.5 0.00011 21.7 2.6 7.4 7 0 0 7 7 6 4 IQ calmodulin-binding motif AAA_22 PF13401.6 CRK26227.1 - 4.5e-08 33.5 1.6 0.0056 17.0 0.0 3.5 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.6 CRK26227.1 - 7.7e-08 32.9 0.8 0.026 14.9 0.0 3.8 3 0 0 3 3 2 2 AAA ATPase domain AAA_17 PF13207.6 CRK26227.1 - 4.9e-06 27.0 0.0 2.7e-05 24.6 0.0 2.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 CRK26227.1 - 7e-05 23.3 1.8 0.047 14.1 0.0 4.2 4 1 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 CRK26227.1 - 0.00013 21.2 0.0 0.07 12.2 0.0 2.8 2 0 0 2 2 2 1 Type II/IV secretion system protein RNA_helicase PF00910.22 CRK26227.1 - 0.00016 22.0 0.0 0.57 10.6 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.6 CRK26227.1 - 0.00027 21.2 0.0 0.0071 16.6 0.0 3.1 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 CRK26227.1 - 0.0013 18.6 0.4 1.9 8.4 0.0 3.2 3 0 0 3 3 3 1 Rad17 P-loop domain GAS PF13851.6 CRK26227.1 - 0.0016 17.9 30.0 0.0018 17.6 14.6 2.8 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding TsaE PF02367.17 CRK26227.1 - 0.0016 18.4 0.0 1.1 9.2 0.0 2.8 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 CRK26227.1 - 0.0022 17.7 0.0 1.5 8.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 CRK26227.1 - 0.0025 17.8 0.0 1.4 8.9 0.0 3.0 2 0 0 2 2 2 1 NACHT domain AAA_30 PF13604.6 CRK26227.1 - 0.0043 16.8 3.1 1.2 8.8 0.0 3.6 3 0 0 3 3 3 1 AAA domain ADK PF00406.22 CRK26227.1 - 0.0053 16.9 0.2 0.069 13.3 0.0 2.8 3 0 0 3 3 2 1 Adenylate kinase Sigma54_activat PF00158.26 CRK26227.1 - 0.0056 16.4 0.0 0.45 10.2 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_7 PF12775.7 CRK26227.1 - 0.018 14.6 0.0 3.3 7.2 0.0 2.7 2 0 0 2 2 2 0 P-loop containing dynein motor region NTPase_1 PF03266.15 CRK26227.1 - 0.023 14.6 3.4 0.078 12.9 0.2 3.2 3 0 0 3 3 3 0 NTPase RsgA_GTPase PF03193.16 CRK26227.1 - 0.032 14.2 0.9 4.3 7.2 0.0 3.3 3 0 0 3 3 3 0 RsgA GTPase Hydin_ADK PF17213.3 CRK26227.1 - 0.044 14.1 0.0 0.044 14.1 0.0 3.0 3 0 0 3 3 2 0 Hydin Adenylate kinase-like domain AAA_19 PF13245.6 CRK26227.1 - 0.05 13.9 7.1 1.6 9.1 0.1 4.0 4 0 0 4 4 3 0 AAA domain Sec34 PF04136.15 CRK26227.1 - 0.056 13.3 14.1 0.026 14.4 4.1 2.8 1 1 1 2 2 2 0 Sec34-like family AAA_33 PF13671.6 CRK26227.1 - 0.062 13.5 9.6 0.22 11.7 0.0 4.8 5 0 0 5 5 4 0 AAA domain Viral_helicase1 PF01443.18 CRK26227.1 - 0.072 12.8 0.0 0.32 10.7 0.0 2.1 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase CbiA PF01656.23 CRK26227.1 - 0.1 12.7 0.7 4.9 7.2 0.1 2.8 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Atg14 PF10186.9 CRK26227.1 - 0.11 11.5 18.1 0.42 9.7 17.9 2.0 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF812 PF05667.11 CRK26227.1 - 0.12 11.3 28.7 0.55 9.1 28.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF812) AAA_13 PF13166.6 CRK26227.1 - 0.13 10.9 16.3 0.31 9.6 16.3 1.6 1 0 0 1 1 1 0 AAA domain KASH_CCD PF14662.6 CRK26227.1 - 0.23 11.3 32.4 1.3 8.9 7.8 3.0 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Thymidylate_kin PF02223.17 CRK26227.1 - 0.27 10.9 8.3 4.5 6.9 0.0 4.3 5 0 0 5 5 3 0 Thymidylate kinase ABC_tran PF00005.27 CRK26227.1 - 0.48 10.9 6.6 2.2 8.8 0.0 3.9 3 1 0 3 3 2 0 ABC transporter Baculo_PEP_C PF04513.12 CRK26227.1 - 0.6 10.1 15.8 0.87 9.6 11.9 3.0 2 1 1 3 3 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3450 PF11932.8 CRK26227.1 - 1 8.6 29.5 1.2 8.4 16.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) FtsK_SpoIIIE PF01580.18 CRK26227.1 - 1.1 8.5 5.9 4.2 6.6 0.0 3.5 4 0 0 4 4 3 0 FtsK/SpoIIIE family CENP-H PF05837.12 CRK26227.1 - 1.5 9.3 28.3 6.7 7.2 6.1 3.1 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DUF3037 PF11236.8 CRK26227.1 - 2.6 8.5 7.2 6.2 7.3 3.6 3.5 3 0 0 3 3 2 0 Protein of unknown function (DUF3037) ATG16 PF08614.11 CRK26227.1 - 2.8 8.1 32.7 4 7.6 29.2 2.9 2 1 0 2 2 1 0 Autophagy protein 16 (ATG16) TPR_MLP1_2 PF07926.12 CRK26227.1 - 3.4 7.7 30.8 1.1 9.3 1.3 3.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein BRE1 PF08647.11 CRK26227.1 - 4.2 7.5 25.1 6.6 6.9 12.9 3.0 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase DUF1664 PF07889.12 CRK26227.1 - 4.3 7.4 15.9 28 4.8 0.6 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 CRK26227.1 - 5 7.7 32.5 1.1 9.8 24.3 2.9 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF5082 PF16888.5 CRK26227.1 - 5 7.4 20.0 10 6.4 12.6 4.1 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) DUF4164 PF13747.6 CRK26227.1 - 5.1 7.4 14.3 1.9 8.8 9.7 2.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) CENP-F_leu_zip PF10473.9 CRK26227.1 - 5.1 7.1 31.4 2.6 8.0 5.4 2.7 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMCO5 PF14992.6 CRK26227.1 - 6.9 6.1 26.3 2.5 7.6 4.6 2.5 1 1 1 2 2 2 0 TMCO5 family TMF_TATA_bd PF12325.8 CRK26227.1 - 9.4 6.5 27.5 6.6 7.0 1.6 3.7 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding 2-Hacid_dh_C PF02826.19 CRK26229.1 - 1.5e-51 174.3 0.0 2.4e-51 173.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CRK26229.1 - 1.4e-32 112.1 0.0 1.9e-32 111.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 CRK26229.1 - 0.00012 22.3 0.2 0.00028 21.1 0.2 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 CRK26229.1 - 0.0019 18.3 0.1 0.0039 17.3 0.1 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.12 CRK26229.1 - 0.0045 16.6 0.1 0.06 12.9 0.0 2.2 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain XdhC_C PF13478.6 CRK26229.1 - 0.021 15.3 0.1 0.11 13.0 0.0 2.1 2 0 0 2 2 2 0 XdhC Rossmann domain Amdase PF17645.1 CRK26229.1 - 0.11 12.1 0.1 0.21 11.2 0.1 1.4 1 0 0 1 1 1 0 Arylmalonate decarboxylase ACT PF01842.25 CRK26229.1 - 0.12 12.2 0.0 0.28 11.0 0.0 1.7 1 0 0 1 1 1 0 ACT domain 3HCDH_N PF02737.18 CRK26229.1 - 0.19 11.6 2.1 4.1 7.2 0.7 2.8 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CMAS PF02353.20 CRK26230.1 - 2.3e-28 99.3 0.2 3e-28 98.9 0.2 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 CRK26230.1 - 3.7e-17 62.8 0.0 5.8e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK26230.1 - 2.5e-16 60.2 0.0 3.9e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK26230.1 - 2.5e-15 56.6 0.0 3.3e-15 56.2 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CRK26230.1 - 3.3e-12 46.6 0.0 4.5e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK26230.1 - 2.7e-11 44.1 0.0 4.4e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CRK26230.1 - 4.3e-08 32.9 0.0 6.9e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 CRK26230.1 - 1.7e-07 30.9 0.0 2.2e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DUF938 PF06080.12 CRK26230.1 - 4.8e-05 23.2 0.0 8.3e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_4 PF02390.17 CRK26230.1 - 0.00011 21.7 0.0 0.00086 18.8 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase TehB PF03848.14 CRK26230.1 - 0.00045 19.7 0.0 0.00075 19.0 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltr_RsmB-F PF01189.17 CRK26230.1 - 0.0018 18.0 0.0 0.0035 17.0 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_2 PF00891.18 CRK26230.1 - 0.0065 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain PCMT PF01135.19 CRK26230.1 - 0.0066 16.2 0.0 0.018 14.8 0.0 1.8 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GidB PF02527.15 CRK26230.1 - 0.025 13.9 0.0 0.037 13.4 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G UQ_con PF00179.26 CRK26232.1 - 3.8e-11 42.8 0.0 6.2e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CRK26232.1 - 0.028 14.7 0.0 0.05 13.9 0.0 1.3 1 0 0 1 1 1 0 RWD domain B-block_TFIIIC PF04182.12 CRK26233.1 - 7.6e-14 51.6 0.0 2e-13 50.3 0.0 1.7 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC MarR_2 PF12802.7 CRK26233.1 - 0.089 12.7 0.3 1.1 9.2 0.0 2.7 2 0 0 2 2 2 0 MarR family AbiEi_1 PF09407.10 CRK26234.1 - 0.3 11.4 1.3 3.3 8.0 0.0 2.1 2 0 0 2 2 2 0 AbiEi antitoxin C-terminal domain Endonuc_Holl PF10107.9 CRK26234.1 - 0.4 10.5 4.5 0.67 9.8 4.5 1.3 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase Cyanate_lyase PF02560.14 CRK26235.1 - 3.6e-32 110.0 0.0 5.9e-32 109.3 0.0 1.3 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_31 PF13560.6 CRK26235.1 - 0.0055 17.0 0.0 0.0075 16.6 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain YdaS_antitoxin PF15943.5 CRK26235.1 - 0.026 14.4 0.0 0.045 13.6 0.0 1.4 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Sigma70_r4_2 PF08281.12 CRK26235.1 - 0.028 14.1 0.1 0.079 12.6 0.0 1.7 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_3 PF01381.22 CRK26235.1 - 0.03 14.4 0.0 0.053 13.6 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix Herpes_LMP1 PF05297.11 CRK26236.1 - 5.9 6.0 7.3 8.3 5.5 7.3 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Ebp2 PF05890.12 CRK26237.1 - 2.1e-83 280.0 17.5 2.1e-83 280.0 17.5 1.3 1 1 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 zf-MYND PF01753.18 CRK26238.1 - 3.3e-08 33.5 19.6 1.2e-07 31.7 19.6 2.0 1 0 0 1 1 1 1 MYND finger SelP_N PF04592.14 CRK26238.1 - 0.053 12.9 22.6 0.089 12.2 11.9 2.3 2 0 0 2 2 2 0 Selenoprotein P, N terminal region APC_u15 PF16636.5 CRK26238.1 - 0.42 11.1 4.5 1.1 9.7 4.5 1.7 1 0 0 1 1 1 0 Unstructured region on APC between APC_crr regions 5 and 6 SPX PF03105.19 CRK26238.1 - 8 6.3 10.0 12 5.6 10.0 1.3 1 0 0 1 1 1 0 SPX domain PqqA PF08042.11 CRK26243.1 - 0.2 11.8 0.1 0.3 11.2 0.1 1.3 1 0 0 1 1 1 0 PqqA family Pkinase PF00069.25 CRK26244.1 - 2.1e-05 24.1 0.1 4.1e-05 23.1 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain S_100 PF01023.19 CRK26244.1 - 0.0025 17.5 0.2 0.0044 16.7 0.2 1.3 1 0 0 1 1 1 1 S-100/ICaBP type calcium binding domain Gag_p6 PF08705.11 CRK26244.1 - 0.0086 16.3 0.1 0.016 15.4 0.1 1.4 1 0 0 1 1 1 1 Gag protein p6 IMS_C PF11799.8 CRK26246.1 - 1.7e-12 48.1 0.2 3.2e-12 47.2 0.2 1.4 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS PF00817.20 CRK26246.1 - 0.00015 21.8 0.3 0.00036 20.5 0.3 1.7 1 0 0 1 1 1 1 impB/mucB/samB family IMS_HHH PF11798.8 CRK26246.1 - 0.0015 18.7 0.0 0.0032 17.7 0.0 1.6 1 0 0 1 1 1 1 IMS family HHH motif Gpr1_Fun34_YaaH PF01184.19 CRK26247.1 - 1.8e-80 269.4 18.4 3.2e-80 268.6 18.4 1.4 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family FAD_binding_2 PF00890.24 CRK26247.1 - 1.4e-60 205.6 12.2 1.7e-60 205.3 12.2 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 CRK26247.1 - 3.1e-08 33.6 6.2 6.2e-08 32.6 6.2 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CRK26247.1 - 9e-08 32.2 0.8 9e-08 32.2 0.8 3.1 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 CRK26247.1 - 3.8e-07 29.8 2.7 1e-06 28.4 2.7 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 CRK26247.1 - 7.3e-06 25.5 1.7 1.2e-05 24.8 1.7 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 CRK26247.1 - 1.7e-05 24.2 0.5 3.1e-05 23.3 0.5 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CRK26247.1 - 0.00036 21.0 0.2 0.042 14.4 0.3 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 CRK26247.1 - 0.0013 18.1 0.3 0.0028 17.0 0.3 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 CRK26247.1 - 0.0014 17.8 1.0 0.0014 17.8 1.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 CRK26247.1 - 0.0028 16.4 0.7 0.0028 16.4 0.7 1.7 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 CRK26247.1 - 0.048 12.9 0.1 0.092 12.0 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase YjeF_N PF03853.15 CRK26247.1 - 0.064 13.1 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus Lycopene_cycl PF05834.12 CRK26247.1 - 0.069 12.2 0.1 0.069 12.2 0.1 2.1 3 0 0 3 3 3 0 Lycopene cyclase protein E_Pc_C PF06752.12 CRK26250.1 - 0.48 10.5 1.9 0.63 10.1 1.9 1.4 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus WSC PF01822.19 CRK26251.1 - 8.3e-21 74.0 8.1 2.7e-20 72.3 8.1 2.0 1 0 0 1 1 1 1 WSC domain WD40 PF00400.32 CRK26252.1 - 1.2e-08 35.5 11.7 0.51 11.3 0.0 8.6 9 0 0 9 9 9 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 CRK26252.1 - 2.7e-05 23.3 0.0 0.0058 15.6 0.0 3.0 4 0 0 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 CRK26252.1 - 3.8e-05 23.9 0.1 0.74 10.2 0.0 5.5 4 1 2 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 CRK26252.1 - 0.0034 17.3 0.1 3.4 7.7 0.0 3.6 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat PQQ_2 PF13360.6 CRK26252.1 - 0.0048 16.5 0.2 0.028 14.0 0.1 2.4 1 1 0 1 1 1 1 PQQ-like domain Nucleoporin_N PF08801.11 CRK26252.1 - 0.0073 15.1 0.0 0.043 12.6 0.0 2.0 2 0 0 2 2 2 1 Nup133 N terminal like BUD22 PF09073.10 CRK26252.1 - 2.4 7.4 12.9 14 4.9 0.1 2.2 2 0 0 2 2 2 0 BUD22 Rad4 PF03835.15 CRK26253.1 - 1.1e-13 51.1 2.8 2.5e-13 50.0 2.8 1.6 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.19 CRK26253.1 - 7.2e-12 45.7 2.1 1.5e-11 44.8 2.1 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily Ank_2 PF12796.7 CRK26254.1 - 5.7e-31 106.9 10.2 2.3e-10 40.9 1.2 7.2 5 1 1 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CRK26254.1 - 8.6e-25 86.8 14.2 7.7e-05 23.2 0.1 8.3 8 1 1 9 9 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 CRK26254.1 - 2e-17 61.5 10.7 0.0013 19.0 0.0 10.6 12 0 0 12 12 10 3 Ankyrin repeat Ank_5 PF13857.6 CRK26254.1 - 2e-14 53.5 9.3 0.00068 19.9 0.0 7.6 5 2 2 7 7 7 3 Ankyrin repeats (many copies) Ank PF00023.30 CRK26254.1 - 7e-12 45.2 17.3 0.0051 17.2 0.0 9.6 9 1 0 9 9 9 3 Ankyrin repeat NACHT PF05729.12 CRK26254.1 - 6.5e-09 35.9 0.0 1.6e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 NACHT domain KAP_NTPase PF07693.14 CRK26254.1 - 1.5e-05 24.4 0.8 0.014 14.6 0.0 2.3 2 0 0 2 2 2 2 KAP family P-loop domain AAA_16 PF13191.6 CRK26254.1 - 0.00033 21.1 0.2 0.0094 16.4 0.0 3.4 4 0 0 4 4 3 1 AAA ATPase domain RNA_helicase PF00910.22 CRK26254.1 - 0.001 19.5 0.1 0.0042 17.5 0.0 2.0 2 0 0 2 2 2 1 RNA helicase AAA PF00004.29 CRK26254.1 - 0.0014 19.1 0.0 0.0045 17.4 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Abhydrolase_6 PF12697.7 CRK26254.1 - 0.0024 18.5 1.4 0.006 17.2 0.1 2.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family ABC_tran PF00005.27 CRK26254.1 - 0.017 15.6 0.0 0.061 13.8 0.0 1.9 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 CRK26254.1 - 0.019 15.2 0.0 0.16 12.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 CRK26254.1 - 0.027 15.0 0.1 0.22 12.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 CRK26254.1 - 0.056 13.3 0.1 0.21 11.5 0.0 1.9 2 0 0 2 2 2 0 NTPase DUF87 PF01935.17 CRK26254.1 - 0.17 11.9 0.0 0.41 10.7 0.0 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain Ribosomal_S5 PF00333.20 CRK26255.1 - 1.8e-27 95.1 1.0 4e-27 94.0 1.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 CRK26255.1 - 1.3e-23 82.2 0.1 2.5e-23 81.3 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Phage_tail_NK PF16532.5 CRK26255.1 - 0.12 12.0 0.1 0.19 11.4 0.1 1.3 1 0 0 1 1 1 0 Sf6-type phage tail needle knob or tip of some Caudovirales FoP_duplication PF13865.6 CRK26255.1 - 1 10.0 14.1 2.2 8.9 14.1 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Rhodanese PF00581.20 CRK26256.1 - 4.2e-18 65.8 0.0 2.7e-10 40.7 0.0 2.4 2 1 0 2 2 2 2 Rhodanese-like domain DAP_epimerase PF01678.19 CRK26256.1 - 0.1 12.8 0.0 2.1 8.6 0.0 2.3 2 0 0 2 2 2 0 Diaminopimelate epimerase zf-ANAPC11 PF12861.7 CRK26257.1 - 2.2e-43 146.2 11.7 4e-43 145.4 11.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 CRK26257.1 - 2.7e-21 75.6 11.9 5.3e-21 74.7 11.9 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CRK26257.1 - 6.5e-07 29.6 14.5 8.3e-06 26.0 14.5 2.4 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CRK26257.1 - 0.00015 21.5 11.4 0.00048 19.9 11.4 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CRK26257.1 - 0.00038 20.4 9.7 0.00085 19.3 4.9 2.5 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CRK26257.1 - 0.003 17.4 7.3 0.003 17.4 7.3 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 CRK26257.1 - 0.0076 16.0 3.0 0.0076 16.0 3.0 2.4 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 CRK26257.1 - 0.013 15.7 15.0 0.17 12.0 15.0 2.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 CRK26257.1 - 0.013 15.7 9.6 0.017 15.2 7.9 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 CRK26257.1 - 0.017 14.9 12.9 0.017 14.9 12.9 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CRK26257.1 - 0.021 14.4 11.3 0.14 11.8 11.3 2.1 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-Nse PF11789.8 CRK26257.1 - 0.038 13.8 4.6 0.085 12.7 4.6 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Rad50_zn_hook PF04423.14 CRK26257.1 - 0.068 13.0 0.6 0.91 9.4 0.0 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_11 PF17123.5 CRK26257.1 - 0.4 10.5 11.0 0.98 9.2 8.6 2.8 2 1 0 2 2 2 0 RING-like zinc finger zf-HIT PF04438.16 CRK26257.1 - 0.49 10.3 4.8 0.24 11.3 1.0 2.1 2 0 0 2 2 2 0 HIT zinc finger zf-RING_5 PF14634.6 CRK26257.1 - 1 9.4 16.8 16 5.6 17.1 2.6 1 1 1 2 2 2 0 zinc-RING finger domain UBZ_FAAP20 PF15750.5 CRK26257.1 - 1.5 8.9 5.5 4.6 7.3 0.3 2.8 2 1 0 2 2 2 0 Ubiquitin-binding zinc-finger YacG PF03884.14 CRK26257.1 - 1.6 8.5 8.2 0.46 10.3 0.5 2.6 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG RINGv PF12906.7 CRK26257.1 - 3 8.0 10.8 9 6.5 10.6 2.0 1 1 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.11 CRK26257.1 - 6.1 7.2 11.6 31 5.0 11.6 2.1 1 1 0 1 1 1 0 RING-like domain Prok-RING_4 PF14447.6 CRK26257.1 - 6.3 6.7 13.1 17 5.3 9.4 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 FBPase PF00316.20 CRK26259.1 - 2.1e-24 86.0 0.0 3.6e-24 85.3 0.0 1.3 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Syntaxin PF00804.25 CRK26260.1 - 2e-18 66.8 9.5 2e-18 66.8 9.5 1.6 1 1 1 2 2 2 1 Syntaxin SNARE PF05739.19 CRK26260.1 - 2.1e-11 43.6 1.2 6.9e-11 42.0 0.4 2.2 2 0 0 2 2 2 1 SNARE domain Mod_r PF07200.13 CRK26260.1 - 0.0034 17.5 7.5 0.14 12.3 3.3 2.2 2 0 0 2 2 2 2 Modifier of rudimentary (Mod(r)) protein LAP1C PF05609.12 CRK26260.1 - 0.0046 16.1 2.5 0.0063 15.7 2.5 1.2 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) TACC_C PF05010.14 CRK26260.1 - 0.0057 16.5 5.4 0.49 10.2 0.0 2.2 2 0 0 2 2 2 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF515 PF04415.12 CRK26260.1 - 0.021 13.2 2.0 0.024 13.0 0.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF515) DUF1676 PF07898.13 CRK26260.1 - 0.033 14.2 0.2 0.051 13.6 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) Arch_flagellin PF01917.16 CRK26260.1 - 0.042 14.0 0.1 0.1 12.8 0.1 1.6 1 0 0 1 1 1 0 Archaebacterial flagellin DUF5305 PF17231.2 CRK26260.1 - 0.081 12.3 0.1 0.15 11.4 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Cytochrome_B PF00033.19 CRK26260.1 - 0.17 11.7 0.3 0.26 11.1 0.3 1.1 1 0 0 1 1 1 0 Cytochrome b/b6/petB HHH_2 PF12826.7 CRK26260.1 - 0.23 11.6 0.9 0.75 9.9 0.5 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix motif MCPsignal PF00015.21 CRK26260.1 - 0.25 11.1 8.9 0.31 10.8 4.6 2.3 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Prominin PF05478.11 CRK26260.1 - 0.43 8.5 4.1 0.72 7.7 3.9 1.4 1 1 0 1 1 1 0 Prominin DUF4709 PF15821.5 CRK26260.1 - 0.47 10.7 8.2 3.4 8.0 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4709) 7tm_7 PF08395.12 CRK26260.1 - 0.69 9.1 0.0 0.69 9.1 0.0 2.4 2 1 0 2 2 2 0 7tm Chemosensory receptor MCU PF04678.13 CRK26260.1 - 1.4 8.9 6.6 0.39 10.8 2.3 1.9 1 1 1 2 2 2 0 Mitochondrial calcium uniporter 4HB_MCP_1 PF12729.7 CRK26260.1 - 3.4 7.2 7.7 1.1 8.8 0.1 2.7 2 1 0 2 2 2 0 Four helix bundle sensory module for signal transduction DUF2203 PF09969.9 CRK26260.1 - 4.7 8.0 8.9 6.6 7.5 3.4 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF2951 PF11166.8 CRK26260.1 - 4.8 7.5 6.0 4.4 7.6 1.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) V-SNARE PF05008.15 CRK26260.1 - 8.1 6.9 13.3 0.63 10.4 3.9 2.9 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus GNAT_acetyltr_2 PF13718.6 CRK26261.1 - 9.5e-100 332.7 0.0 1.7e-99 331.8 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 CRK26261.1 - 5e-93 311.1 0.1 8.7e-93 310.4 0.1 1.4 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 CRK26261.1 - 1.9e-65 220.0 0.0 7.3e-65 218.1 0.0 2.1 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 CRK26261.1 - 1.3e-32 111.6 0.0 3.5e-32 110.2 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) AAA_30 PF13604.6 CRK26261.1 - 6.7e-05 22.7 0.1 0.0076 16.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CRK26261.1 - 0.00079 19.7 0.0 0.042 14.1 0.0 3.0 2 0 0 2 2 2 1 AAA domain GHMP_kinases_N PF00288.26 CRK26261.1 - 0.058 13.6 0.1 0.17 12.1 0.1 1.8 1 0 0 1 1 1 0 GHMP kinases N terminal domain PG_binding_1 PF01471.18 CRK26262.1 - 0.013 15.7 0.0 4.4 7.6 0.0 2.8 2 0 0 2 2 2 0 Putative peptidoglycan binding domain WD40 PF00400.32 CRK26263.1 - 1.3e-14 54.3 8.9 0.00014 22.6 0.0 9.9 12 0 0 12 12 12 2 WD domain, G-beta repeat Nup160 PF11715.8 CRK26263.1 - 0.063 11.9 0.0 22 3.5 0.0 3.3 3 1 0 3 3 3 0 Nucleoporin Nup120/160 DUF4392 PF14336.6 CRK26265.1 - 0.21 11.0 0.0 0.22 10.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) Nucleoporin_FG PF13634.6 CRK26265.1 - 1 10.3 10.5 0.72 10.7 8.4 1.7 1 1 0 1 1 1 0 Nucleoporin FG repeat region Aldolase_II PF00596.21 CRK26266.1 - 7e-28 97.8 0.3 8.6e-28 97.5 0.3 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain SelR PF01641.18 CRK26267.1 - 9.6e-39 132.2 0.8 1.1e-38 132.1 0.8 1.0 1 0 0 1 1 1 1 SelR domain zinc_ribbon_10 PF10058.9 CRK26267.1 - 0.011 15.4 0.1 0.18 11.6 0.0 2.1 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein DZR PF12773.7 CRK26267.1 - 0.017 15.2 2.5 1.3 9.1 0.2 2.3 2 1 0 2 2 2 0 Double zinc ribbon Yippee-Mis18 PF03226.14 CRK26267.1 - 0.07 13.3 0.4 0.29 11.4 0.4 1.8 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-Mss51 PF13824.6 CRK26267.1 - 0.34 11.0 3.3 11 6.2 0.2 3.1 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 Fungal_trans PF04082.18 CRK26271.1 - 5.6e-38 130.5 0.0 5.6e-38 130.5 0.0 2.9 3 1 1 4 4 4 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK26271.1 - 0.0015 18.6 1.2 0.0026 17.8 1.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Anoctamin PF04547.12 CRK26271.1 - 0.11 11.3 3.5 0.17 10.7 3.5 1.2 1 0 0 1 1 1 0 Calcium-activated chloride channel MukE PF04288.13 CRK26271.1 - 0.22 10.4 1.4 20 4.0 0.0 2.2 2 0 0 2 2 2 0 MukE-like family EMC3_TMCO1 PF01956.16 CRK26271.1 - 4 7.1 6.3 11 5.7 3.9 2.3 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like PigN PF04987.14 CRK26272.1 - 1.6e-142 475.6 14.7 1.6e-142 475.6 14.7 1.9 2 0 0 2 2 2 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 CRK26272.1 - 6.3e-09 35.9 2.9 5.3e-07 29.5 2.9 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 CRK26272.1 - 2e-08 34.0 0.1 3.2e-08 33.3 0.1 1.4 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 CRK26272.1 - 4.5e-05 22.9 0.0 7.1e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily PglZ PF08665.12 CRK26272.1 - 0.061 13.4 0.1 0.12 12.5 0.1 1.4 1 0 0 1 1 1 0 PglZ domain Csm1 PF12539.8 CRK26273.1 - 3.4e-34 117.3 0.1 7.5e-34 116.2 0.1 1.6 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 OEP PF02321.18 CRK26273.1 - 0.00028 20.8 8.8 0.00051 19.9 8.8 1.4 1 0 0 1 1 1 1 Outer membrane efflux protein CCDC158 PF15921.5 CRK26273.1 - 0.0041 15.0 3.9 0.0058 14.5 3.9 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 158 AT_hook PF02178.19 CRK26273.1 - 0.029 14.2 11.5 0.2 11.6 6.3 2.8 2 0 0 2 2 2 0 AT hook motif DUF5094 PF17015.5 CRK26273.1 - 0.13 12.4 1.5 0.34 11.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5094) XhlA PF10779.9 CRK26273.1 - 0.16 12.2 5.8 0.13 12.5 0.6 2.7 2 1 0 2 2 2 0 Haemolysin XhlA UPF0242 PF06785.11 CRK26273.1 - 0.17 12.0 2.2 0.41 10.7 2.2 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Csm1_N PF18504.1 CRK26273.1 - 0.23 11.8 2.4 6.4 7.2 1.0 2.7 2 0 0 2 2 2 0 Csm1 N-terminal domain Phage_GP20 PF06810.11 CRK26273.1 - 1.3 8.8 3.9 16 5.3 0.2 2.3 1 1 1 2 2 2 0 Phage minor structural protein GP20 Flagellin_C PF00700.21 CRK26273.1 - 4 7.9 6.0 0.71 10.3 0.3 2.7 3 0 0 3 3 3 0 Bacterial flagellin C-terminal helical region DUF4407 PF14362.6 CRK26273.1 - 7.8 5.7 13.6 0.37 10.1 6.6 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) AAA PF00004.29 CRK26274.1 - 4e-37 127.6 0.0 6.5e-37 126.9 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CRK26274.1 - 2.7e-09 36.7 0.0 5.9e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_14 PF13173.6 CRK26274.1 - 3.1e-05 24.0 0.0 5.6e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 CRK26274.1 - 4.8e-05 23.1 0.0 0.00016 21.5 0.0 1.9 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 CRK26274.1 - 0.00011 22.3 0.0 0.00021 21.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 CRK26274.1 - 0.00011 22.6 0.2 0.005 17.2 0.0 2.6 2 1 0 3 3 2 1 AAA ATPase domain AAA_22 PF13401.6 CRK26274.1 - 0.00019 21.7 0.1 0.11 12.8 0.1 3.1 1 1 2 3 3 3 1 AAA domain AAA_33 PF13671.6 CRK26274.1 - 0.0011 19.1 0.0 0.0027 17.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CRK26274.1 - 0.0025 17.8 0.1 0.018 15.0 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TniB PF05621.11 CRK26274.1 - 0.0029 17.0 0.0 1.2 8.5 0.0 2.5 1 1 1 2 2 2 1 Bacterial TniB protein Zeta_toxin PF06414.12 CRK26274.1 - 0.007 15.7 0.1 0.063 12.5 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin Mg_chelatase PF01078.21 CRK26274.1 - 0.0072 15.7 0.0 0.015 14.6 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 CRK26274.1 - 0.0097 16.3 0.0 0.026 14.9 0.0 1.9 1 0 0 1 1 1 1 RNA helicase AAA_28 PF13521.6 CRK26274.1 - 0.033 14.4 0.0 0.082 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain PocR PF10114.9 CRK26274.1 - 0.037 13.8 0.0 7.7 6.3 0.0 2.3 2 0 0 2 2 2 0 Sensory domain found in PocR DUF815 PF05673.13 CRK26274.1 - 0.04 13.1 0.0 0.077 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 CRK26274.1 - 0.041 13.6 0.0 0.1 12.3 0.0 1.6 2 0 0 2 2 1 0 Sigma-54 interaction domain NACHT PF05729.12 CRK26274.1 - 0.046 13.6 0.0 0.093 12.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 CRK26274.1 - 0.069 12.7 0.0 0.16 11.5 0.0 1.5 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 CRK26274.1 - 0.072 13.6 0.3 0.22 12.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 CRK26274.1 - 0.081 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 CRK26274.1 - 0.085 12.4 0.8 0.99 8.9 0.1 2.6 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.22 CRK26274.1 - 0.09 11.9 0.0 0.52 9.5 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain Viral_helicase1 PF01443.18 CRK26274.1 - 0.099 12.4 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 CRK26274.1 - 0.12 12.9 0.0 0.33 11.5 0.0 1.8 1 1 0 1 1 1 0 ABC transporter Nitr_red_bet_C PF14711.6 CRK26274.1 - 0.13 12.0 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Respiratory nitrate reductase beta C-terminal Bac_DnaA PF00308.18 CRK26274.1 - 0.17 11.7 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein TsaE PF02367.17 CRK26274.1 - 0.18 11.8 0.0 0.36 10.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 CRK26274.1 - 0.19 10.9 0.0 0.41 9.8 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain Cys_Met_Meta_PP PF01053.20 CRK26275.1 - 3.1e-137 457.2 0.0 3.5e-137 457.0 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 CRK26275.1 - 6.4e-07 28.9 0.0 1e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 CRK26275.1 - 4.9e-06 25.7 0.0 1.1e-05 24.6 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V Met_gamma_lyase PF06838.11 CRK26275.1 - 0.00013 20.6 0.2 0.00047 18.8 0.2 1.7 1 1 0 1 1 1 1 Methionine gamma-lyase DegT_DnrJ_EryC1 PF01041.17 CRK26275.1 - 0.0013 18.1 0.1 0.0052 16.1 0.0 1.8 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family DEDD_Tnp_IS110 PF01548.17 CRK26275.1 - 0.031 14.1 0.0 0.49 10.3 0.0 2.2 2 0 0 2 2 2 0 Transposase GDC-P PF02347.16 CRK26275.1 - 0.064 12.1 0.1 0.097 11.5 0.1 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 CRK26275.1 - 0.09 12.0 0.0 0.42 9.8 0.0 1.9 2 0 0 2 2 2 0 Beta-eliminating lyase Pantoate_transf PF02548.15 CRK26275.1 - 0.13 11.6 2.2 1.5 8.1 0.5 2.4 2 0 0 2 2 2 0 Ketopantoate hydroxymethyltransferase Serinc PF03348.15 CRK26276.1 - 3.6e-162 540.2 10.5 4.1e-162 540.0 10.5 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) DUF809 PF05663.11 CRK26276.1 - 0.2 11.8 0.2 0.53 10.4 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF809) Cation_efflux PF01545.21 CRK26276.1 - 2.7 7.7 15.4 3.8 7.2 11.4 3.0 3 1 0 3 3 3 0 Cation efflux family MFS_1 PF07690.16 CRK26277.1 - 3.6e-11 42.6 34.3 6.4e-05 22.0 2.1 4.1 3 1 0 3 3 3 3 Major Facilitator Superfamily Nodulin-like PF06813.13 CRK26277.1 - 0.00015 21.4 3.3 0.019 14.5 0.5 2.6 1 1 1 2 2 2 2 Nodulin-like MFS_2 PF13347.6 CRK26277.1 - 0.38 9.2 12.1 0.11 11.0 1.7 3.1 2 1 1 3 3 3 0 MFS/sugar transport protein PGAP1 PF07819.13 CRK26278.1 - 1.7e-89 299.5 0.0 2.7e-89 298.8 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 CRK26278.1 - 0.0013 19.4 0.0 0.0039 17.8 0.0 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CRK26278.1 - 0.0031 17.2 0.0 0.0072 16.0 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Palm_thioest PF02089.15 CRK26278.1 - 0.0078 16.1 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Hydrolase_4 PF12146.8 CRK26278.1 - 0.013 14.8 0.0 0.035 13.4 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF676 PF05057.14 CRK26278.1 - 0.04 13.4 0.1 0.077 12.5 0.1 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) LCAT PF02450.15 CRK26278.1 - 0.063 12.4 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_5 PF12695.7 CRK26278.1 - 0.17 11.6 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF3464 PF11947.8 CRK26278.1 - 0.19 11.4 0.1 0.81 9.4 0.0 2.0 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 MutL_C PF08676.11 CRK26279.1 - 8.5e-21 74.3 0.0 2e-20 73.0 0.0 1.7 1 1 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 CRK26279.1 - 7.1e-19 67.6 0.0 1.9e-18 66.3 0.0 1.7 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 CRK26279.1 - 5.3e-13 49.0 0.0 1.7e-12 47.4 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CRK26279.1 - 6e-06 26.7 0.0 1.7e-05 25.3 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SWIRM PF04433.17 CRK26281.1 - 7.1e-31 106.4 0.1 1.6e-30 105.2 0.1 1.7 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 CRK26281.1 - 1.4e-29 101.9 5.4 3e-29 100.8 5.4 1.6 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 CRK26281.1 - 4.2e-10 39.7 0.1 1.1e-09 38.3 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Pyr_redox_2 PF07992.14 CRK26281.1 - 1.6e-06 27.5 0.0 4.6e-05 22.8 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Myb_DNA-bind_6 PF13921.6 CRK26281.1 - 6.6e-06 26.3 0.4 3.5e-05 24.0 0.2 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain NAD_binding_8 PF13450.6 CRK26281.1 - 0.04 14.1 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ETF PF01012.21 CRK26282.1 - 5.6e-42 143.7 3.8 1.4e-41 142.4 2.5 1.9 1 1 1 2 2 2 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 CRK26282.1 - 3.8e-11 42.9 0.2 1.1e-10 41.4 0.2 1.7 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain Carn_acyltransf PF00755.20 CRK26283.1 - 4.2e-194 646.5 3.6 3.6e-192 640.1 3.6 2.0 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase Phycobilisome PF00502.19 CRK26283.1 - 0.12 12.3 0.1 0.25 11.3 0.1 1.4 1 0 0 1 1 1 0 Phycobilisome protein CAP_N PF01213.19 CRK26284.1 - 1.5e-115 386.1 0.4 2.1e-115 385.6 0.4 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 CRK26284.1 - 1.5e-56 190.4 2.8 2.1e-56 189.9 2.8 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal PfkB PF00294.24 CRK26285.1 - 7.7e-15 55.0 0.0 9.4e-09 35.0 0.1 2.2 2 0 0 2 2 2 2 pfkB family carbohydrate kinase Exo70 PF03081.15 CRK26286.1 - 2.8e-91 306.4 0.0 8.9e-91 304.7 0.0 1.7 2 0 0 2 2 2 1 Exo70 exocyst complex subunit Baculo_PEP_C PF04513.12 CRK26286.1 - 0.01 15.9 7.0 0.48 10.5 0.2 3.8 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.18 CRK26286.1 - 0.031 14.1 0.3 0.031 14.1 0.3 3.4 3 1 0 3 3 3 0 Apolipoprotein A1/A4/E domain GAS PF13851.6 CRK26286.1 - 1.4 8.3 9.4 3.4 7.0 0.6 3.9 3 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding DUF2203 PF09969.9 CRK26286.1 - 3.3 8.4 7.0 1.3 9.8 0.1 3.5 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2203) NPV_P10 PF05531.12 CRK26286.1 - 9.2 6.8 6.1 55 4.3 0.1 4.4 6 0 0 6 6 6 0 Nucleopolyhedrovirus P10 protein 2_5_RNA_ligase2 PF13563.6 CRK26287.1 - 4.4e-21 75.4 0.1 9.4e-21 74.3 0.1 1.6 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily PAP_central PF04928.17 CRK26287.1 - 1.8e-18 66.4 0.0 4.3e-18 65.2 0.0 1.6 1 1 0 1 1 1 1 Poly(A) polymerase central domain Exo_endo_phos PF03372.23 CRK26287.1 - 4.6e-05 23.0 0.0 0.00017 21.2 0.0 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family NTP_transf_2 PF01909.23 CRK26287.1 - 0.0018 18.5 0.0 0.0041 17.4 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 CRK26287.1 - 0.17 11.6 0.7 0.29 10.9 0.0 1.7 2 0 0 2 2 2 0 Nrap protein PAP/OAS-like domain KH_1 PF00013.29 CRK26289.1 - 0.018 14.8 0.0 0.03 14.2 0.0 1.5 1 1 0 1 1 1 0 KH domain Cpn60_TCP1 PF00118.24 CRK26290.1 - 1.3e-12 47.2 0.0 1.6e-12 46.9 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family HSP90 PF00183.18 CRK26291.1 - 8e-136 454.0 26.6 7.9e-106 355.0 5.7 2.1 1 1 1 2 2 2 2 Hsp90 protein Vps5 PF09325.10 CRK26291.1 - 1.3e-07 31.4 0.4 1.3e-07 31.4 0.4 2.3 3 0 0 3 3 3 1 Vps5 C terminal like HATPase_c PF02518.26 CRK26291.1 - 0.014 15.9 0.0 0.028 14.9 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_4 PF08448.10 CRK26293.1 - 0.072 13.4 0.1 0.1 12.9 0.1 1.2 1 0 0 1 1 1 0 PAS fold Glyco_hydro_3_C PF01915.22 CRK26296.1 - 1.3e-47 162.4 0.0 2.2e-47 161.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 CRK26296.1 - 6e-38 131.0 0.0 9.2e-38 130.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 CRK26296.1 - 2.2e-21 75.7 0.2 3.9e-21 74.9 0.2 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain FMN_dh PF01070.18 CRK26298.1 - 3.4e-82 276.3 0.1 4.7e-82 275.8 0.1 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 CRK26298.1 - 8.9e-08 31.7 0.1 1.3e-07 31.1 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase Cyt-b5 PF00173.28 CRK26298.1 - 8.6e-06 25.8 0.1 1.9e-05 24.7 0.1 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.25 CRK26298.1 - 0.00032 19.8 0.5 0.0022 17.0 0.3 2.0 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain DUF4150 PF13665.6 CRK26298.1 - 0.033 14.3 0.0 0.08 13.1 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4150) NMO PF03060.15 CRK26298.1 - 0.034 13.5 0.6 0.06 12.7 0.6 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase His_biosynth PF00977.21 CRK26298.1 - 0.73 9.3 3.4 2.7 7.4 0.1 2.4 2 1 0 3 3 3 0 Histidine biosynthesis protein Bac_rhamnosid6H PF17389.2 CRK26300.1 - 1.8e-12 47.2 0.8 3.4e-12 46.3 0.8 1.3 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Trehalase PF01204.18 CRK26300.1 - 1.1e-05 24.5 0.6 1.6e-05 23.9 0.6 1.2 1 0 0 1 1 1 1 Trehalase GDE_C PF06202.14 CRK26300.1 - 0.07 12.1 2.2 0.21 10.5 2.2 1.8 1 1 0 1 1 1 0 Amylo-alpha-1,6-glucosidase MBOAT PF03062.19 CRK26302.1 - 2.9e-38 132.1 11.9 9.9e-38 130.4 11.9 1.9 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Pex14_N PF04695.13 CRK26302.1 - 0.0058 17.3 2.0 1.9 9.1 0.8 3.0 2 1 0 2 2 2 2 Peroxisomal membrane anchor protein (Pex14p) conserved region Zn_clus PF00172.18 CRK26304.1 - 3.3e-10 39.9 10.6 5.4e-10 39.2 10.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 CRK26304.1 - 9.4e-06 24.8 3.3 9.4e-06 24.8 3.3 2.4 2 1 0 2 2 2 1 Fungal specific transcription factor domain MAGUK_N_PEST PF10608.9 CRK26304.1 - 0.002 18.5 0.0 37 4.8 7.3 2.7 2 1 0 2 2 2 1 Polyubiquitination (PEST) N-terminal domain of MAGUK Ribonuclease_T2 PF00445.18 CRK26306.1 - 9.8e-35 120.4 0.0 1.4e-34 120.0 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family Clr5 PF14420.6 CRK26309.1 - 0.0018 18.5 0.0 0.0037 17.5 0.0 1.6 1 0 0 1 1 1 1 Clr5 domain Abhydrolase_3 PF07859.13 CRK26311.1 - 9.9e-13 48.4 0.0 1.3e-12 48.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 CRK26311.1 - 0.021 14.4 0.0 0.024 14.2 0.0 1.1 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 CRK26313.1 - 8.7e-24 84.6 4.3 1.1e-23 84.2 4.3 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 CRK26313.1 - 1.6e-05 24.0 0.2 2.8e-05 23.2 0.2 1.4 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 CRK26313.1 - 0.0006 19.4 0.0 0.00081 18.9 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.12 CRK26313.1 - 0.0071 15.1 0.2 0.012 14.3 0.2 1.4 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Say1_Mug180 PF10340.9 CRK26313.1 - 0.071 11.9 0.1 2.4 6.9 0.0 2.0 2 0 0 2 2 2 0 Steryl acetyl hydrolase Abhydro_lipase PF04083.16 CRK26313.1 - 0.095 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region zf-FPG_IleRS PF06827.14 CRK26315.1 - 0.013 15.4 0.5 0.34 10.8 0.1 2.2 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS DNA_primase_lrg PF04104.14 CRK26317.1 - 1.3e-80 270.7 0.0 1.8e-80 270.1 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Clr5 PF14420.6 CRK26319.1 - 1e-18 67.3 2.9 1.9e-18 66.4 2.9 1.5 1 0 0 1 1 1 1 Clr5 domain EFTUD2 PF16004.5 CRK26324.1 - 0.59 10.7 4.6 8.6 7.0 0.1 2.1 1 1 1 2 2 2 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus Glyco_hydro_76 PF03663.14 CRK26325.1 - 2.7e-40 139.1 0.5 2.9e-40 138.9 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Synaptobrevin PF00957.21 CRK26326.1 - 6.1e-28 96.4 0.8 6.6e-28 96.3 0.8 1.0 1 0 0 1 1 1 1 Synaptobrevin DUF1100 PF06500.11 CRK26326.1 - 0.079 11.7 0.0 0.083 11.7 0.0 1.0 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) AKNA PF12443.8 CRK26326.1 - 0.095 13.4 0.0 0.097 13.3 0.0 1.1 1 0 0 1 1 1 0 AT-hook-containing transcription factor CDC37_M PF08565.11 CRK26327.1 - 6.1e-31 106.8 0.0 6.9e-31 106.6 0.0 1.0 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain BSP PF04450.12 CRK26327.1 - 0.1 12.4 0.0 0.12 12.2 0.0 1.2 1 1 0 1 1 1 0 Peptidase of plants and bacteria CRISPR_Cse2 PF09485.10 CRK26329.1 - 0.049 14.1 0.8 0.049 14.1 0.8 1.5 1 1 1 2 2 2 0 CRISPR-associated protein Cse2 (CRISPR_cse2) zf-MYND PF01753.18 CRK26331.1 - 0.0046 17.0 9.6 0.011 15.8 9.6 1.7 1 0 0 1 1 1 1 MYND finger Ish1 PF10281.9 CRK26332.1 - 3.2e-110 360.1 27.9 3.1e-15 56.2 0.0 9.5 9 0 0 9 9 9 9 Putative stress-responsive nuclear envelope protein SAP PF02037.27 CRK26332.1 - 3.7e-12 45.7 0.0 0.87 9.4 0.0 9.1 11 0 0 11 11 11 2 SAP domain HeH PF12949.7 CRK26332.1 - 1.9e-07 30.7 0.0 1.9 8.3 0.0 7.2 7 1 1 8 8 8 1 HeH/LEM domain Slx4 PF09494.10 CRK26332.1 - 8.1e-07 28.9 4.5 20 5.2 0.0 7.7 9 0 0 9 9 9 0 Slx4 endonuclease CPSase_sm_chain PF00988.22 CRK26332.1 - 0.00011 22.0 0.0 2.8 7.8 0.0 5.0 4 2 2 6 6 6 1 Carbamoyl-phosphate synthase small chain, CPSase domain SAM_2 PF07647.17 CRK26332.1 - 0.00032 20.7 3.3 2.8 8.1 0.1 4.5 5 0 0 5 5 5 2 SAM domain (Sterile alpha motif) DUF4805 PF16063.5 CRK26332.1 - 0.019 14.3 1.3 0.054 12.8 0.7 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4805) BRK PF07533.16 CRK26332.1 - 0.57 9.8 4.7 33 4.2 0.1 3.8 4 0 0 4 4 4 0 BRK domain Apolipoprotein PF01442.18 CRK26332.1 - 1.2 9.0 6.1 14 5.5 0.0 3.8 4 1 0 4 4 4 0 Apolipoprotein A1/A4/E domain SAM_1 PF00536.30 CRK26332.1 - 3.2 8.3 5.2 42 4.7 0.1 3.2 4 0 0 4 4 4 0 SAM domain (Sterile alpha motif) Hydrophobin_2 PF06766.11 CRK26333.1 - 2.9e-28 97.6 10.1 3.6e-28 97.3 10.1 1.1 1 0 0 1 1 1 1 Fungal hydrophobin AAA PF00004.29 CRK26334.1 - 1.1e-39 135.9 0.0 2e-39 135.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 CRK26334.1 - 1.7e-18 66.3 0.1 3.6e-18 65.3 0.1 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 CRK26334.1 - 4.5e-09 36.0 0.0 9.4e-09 35.0 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 CRK26334.1 - 0.00013 22.4 1.8 0.018 15.4 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 CRK26334.1 - 0.00014 21.9 0.1 0.00072 19.6 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CRK26334.1 - 0.00039 20.2 0.0 0.00094 18.9 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 CRK26334.1 - 0.0036 17.4 1.4 0.011 15.9 0.0 2.4 2 1 0 2 2 1 1 AAA domain (Cdc48 subfamily) PhoH PF02562.16 CRK26334.1 - 0.0061 16.0 0.2 0.083 12.3 0.1 2.2 2 0 0 2 2 2 1 PhoH-like protein AAA_22 PF13401.6 CRK26334.1 - 0.0073 16.6 4.1 0.083 13.2 0.0 3.0 3 1 0 4 4 3 1 AAA domain Mg_chelatase PF01078.21 CRK26334.1 - 0.011 15.2 0.0 0.025 13.9 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 CRK26334.1 - 0.016 15.4 0.0 0.034 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 CRK26334.1 - 0.019 14.1 0.0 0.041 13.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 CRK26334.1 - 0.075 12.8 0.1 0.18 11.5 0.1 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 CRK26334.1 - 0.13 11.7 0.0 0.34 10.4 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_11 PF13086.6 CRK26334.1 - 0.35 10.6 5.9 0.62 9.8 0.0 2.6 3 0 0 3 3 3 0 AAA domain RPN2_C PF18004.1 CRK26334.1 - 0.95 9.4 5.8 2.1 8.3 5.8 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain tRNA_lig_CPD PF08302.11 CRK26336.1 - 4.9e-89 298.1 0.0 7e-89 297.6 0.0 1.2 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain RNA_lig_T4_1 PF09511.10 CRK26336.1 - 4.2e-59 200.1 0.0 2e-58 197.9 0.0 1.9 2 0 0 2 2 2 1 RNA ligase tRNA_lig_kinase PF08303.11 CRK26336.1 - 4e-53 180.0 0.0 8e-53 179.0 0.0 1.5 1 0 0 1 1 1 1 tRNA ligase kinase domain 2_5_RNA_ligase2 PF13563.6 CRK26336.1 - 0.11 12.4 0.5 0.45 10.4 0.1 2.2 2 1 0 2 2 2 0 2'-5' RNA ligase superfamily AAA_18 PF13238.6 CRK26336.1 - 0.11 13.0 0.0 0.4 11.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain Ribonuc_P_40 PF08584.11 CRK26337.1 - 5e-54 183.5 0.0 7.4e-53 179.7 0.0 2.0 2 0 0 2 2 2 1 Ribonuclease P 40kDa (Rpp40) subunit 5-nucleotidase PF06189.12 CRK26337.1 - 0.16 10.8 0.0 0.22 10.4 0.0 1.1 1 0 0 1 1 1 0 5'-nucleotidase UPF0020 PF01170.18 CRK26339.1 - 0.014 15.0 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Vac_ImportDeg PF09783.9 CRK26340.1 - 5.7e-69 231.1 1.3 7.4e-69 230.7 1.3 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein Podoplanin PF05808.11 CRK26340.1 - 0.43 10.7 4.5 0.84 9.7 4.5 1.4 1 0 0 1 1 1 0 Podoplanin Mago_nashi PF02792.14 CRK26341.1 - 8.7e-73 243.1 0.2 9.8e-73 242.9 0.2 1.0 1 0 0 1 1 1 1 Mago nashi protein Adaptin_N PF01602.20 CRK26342.1 - 5.5e-94 315.6 7.7 9.1e-94 314.9 7.7 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 CRK26342.1 - 3.2e-59 198.9 0.3 7.1e-59 197.7 0.3 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.6 CRK26342.1 - 6.1e-57 191.1 0.0 1.7e-56 189.7 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Cnd1 PF12717.7 CRK26342.1 - 1.3e-14 54.5 2.9 1.2e-10 41.7 0.0 3.1 1 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CRK26342.1 - 1.4e-09 38.2 1.4 0.003 17.9 0.0 5.1 1 1 3 4 4 4 2 HEAT repeats HEAT PF02985.22 CRK26342.1 - 0.00021 21.3 0.6 2.1 8.8 0.0 4.6 4 0 0 4 4 4 1 HEAT repeat Coatomer_g_Cpla PF16381.5 CRK26342.1 - 0.0007 19.7 0.0 0.002 18.2 0.0 1.9 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform DUF5578 PF17741.1 CRK26342.1 - 0.0038 16.7 1.8 0.7 9.3 0.3 2.8 2 1 0 2 2 2 2 Family of unknown function (DUF5578) AP4E_app_platf PF14807.6 CRK26342.1 - 0.013 15.8 0.2 0.043 14.2 0.2 1.9 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform DUF5071 PF16804.5 CRK26342.1 - 5.4 7.3 8.9 9.8 6.5 0.0 3.5 3 1 1 4 4 4 0 Domain of unknown function (DUF5071) Pre-SET PF05033.16 CRK26343.1 - 1.1e-18 67.9 3.2 3.6e-17 63.0 1.6 2.3 2 0 0 2 2 2 2 Pre-SET motif SET PF00856.28 CRK26343.1 - 1e-17 65.0 0.0 1.1e-16 61.7 0.0 2.5 2 2 0 2 2 2 1 SET domain Glyco_hydro_7 PF00840.20 CRK26344.1 - 1.4e-74 251.4 2.8 1.1e-64 218.8 0.9 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 7 Nop52 PF05997.12 CRK26345.1 - 1.4e-39 136.1 0.4 1.8e-39 135.8 0.4 1.0 1 0 0 1 1 1 1 Nucleolar protein,Nop52 Acyl-CoA_dh_1 PF00441.24 CRK26347.1 - 2.2e-42 144.8 1.4 3.9e-42 144.0 1.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CRK26347.1 - 1.3e-29 103.1 0.0 2.6e-29 102.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 CRK26347.1 - 1.4e-27 95.7 0.2 2.8e-27 94.8 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 CRK26347.1 - 6.3e-15 55.6 0.2 6.3e-15 55.6 0.2 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 CRK26347.1 - 7e-05 22.6 0.5 0.00019 21.2 0.5 1.7 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Hydrolase PF00702.26 CRK26348.1 - 4.4e-13 50.0 0.0 2.1e-12 47.8 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CRK26348.1 - 0.0028 17.4 0.1 0.011 15.5 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cpn60_TCP1 PF00118.24 CRK26353.1 - 1.2e-172 575.0 0.4 1.4e-172 574.8 0.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Vac7 PF12751.7 CRK26354.1 - 1.1 8.6 4.9 1.9 7.9 4.6 1.5 1 1 0 1 1 1 0 Vacuolar segregation subunit 7 Podoplanin PF05808.11 CRK26355.1 - 0.0011 19.1 0.3 0.0016 18.6 0.3 1.3 1 0 0 1 1 1 1 Podoplanin MGC-24 PF05283.11 CRK26355.1 - 0.002 18.6 1.1 0.002 18.6 1.1 1.5 2 0 0 2 2 2 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin CbtA PF09490.10 CRK26355.1 - 0.015 15.0 0.2 0.02 14.7 0.2 1.2 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) DUF4690 PF15756.5 CRK26355.1 - 0.017 15.7 1.3 0.052 14.1 1.3 1.8 1 0 0 1 1 1 0 Small Novel Rich in Cartilage Tir_receptor_N PF07490.11 CRK26355.1 - 0.03 14.2 2.6 0.048 13.5 2.6 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus EphA2_TM PF14575.6 CRK26355.1 - 0.03 15.2 0.0 0.06 14.2 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain CcmD PF04995.14 CRK26355.1 - 0.044 13.9 2.0 0.044 13.9 2.0 1.7 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Yip1 PF04893.17 CRK26355.1 - 0.047 13.4 0.0 0.068 12.9 0.0 1.2 1 0 0 1 1 1 0 Yip1 domain SKG6 PF08693.10 CRK26355.1 - 0.049 13.0 1.8 0.11 12.0 1.8 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain ATG22 PF11700.8 CRK26355.1 - 0.066 11.8 0.0 0.089 11.4 0.0 1.1 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like Sugar_tr PF00083.24 CRK26356.1 - 6.4e-07 28.6 0.0 7.8e-07 28.3 0.0 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK26357.1 - 3.1e-21 75.7 35.2 6.2e-18 64.8 20.0 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK26357.1 - 0.00036 19.5 3.8 0.001 18.0 1.1 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter NUDIX_4 PF14815.6 CRK26359.1 - 6.3e-23 80.9 0.1 1.3e-22 79.8 0.1 1.6 1 0 0 1 1 1 1 NUDIX domain HhH-GPD PF00730.25 CRK26359.1 - 8.2e-18 64.8 0.0 1.7e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein PBP PF01161.20 CRK26359.1 - 4.6e-16 59.3 0.0 8.5e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein HHH PF00633.23 CRK26359.1 - 1.5e-05 24.6 0.0 3.2e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif GREB1 PF15782.5 CRK26359.1 - 3.5 4.6 8.7 4.7 4.2 8.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer TMEM154 PF15102.6 CRK26360.1 - 0.049 13.5 3.1 0.1 12.5 1.9 2.1 1 1 1 2 2 2 0 TMEM154 protein family Macoilin PF09726.9 CRK26360.1 - 0.058 12.0 1.9 0.069 11.7 1.9 1.1 1 0 0 1 1 1 0 Macoilin family ETF_alpha PF00766.19 CRK26360.1 - 0.061 13.4 0.3 0.11 12.6 0.3 1.3 1 0 0 1 1 1 0 Electron transfer flavoprotein FAD-binding domain FtsK_4TM PF13491.6 CRK26360.1 - 0.17 11.6 0.0 0.27 10.9 0.0 1.2 1 0 0 1 1 1 0 4TM region of DNA translocase FtsK/SpoIIIE DUF4010 PF13194.6 CRK26360.1 - 0.17 11.5 0.6 0.27 10.9 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4010) Apt1 PF10351.9 CRK26360.1 - 0.32 9.8 5.2 0.15 10.9 3.3 1.4 2 0 0 2 2 2 0 Golgi-body localisation protein domain Bac_rhamnosid6H PF17389.2 CRK26362.1 - 9.8e-97 324.2 0.1 1.4e-95 320.5 0.0 2.0 1 1 1 2 2 2 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 CRK26362.1 - 1.7e-46 158.2 0.0 3e-46 157.4 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid_C PF17390.2 CRK26362.1 - 4.1e-19 68.2 0.1 8.7e-19 67.1 0.1 1.5 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Bac_rhamnosid PF05592.11 CRK26362.1 - 1.3e-16 60.4 0.0 2.7e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Sugar_tr PF00083.24 CRK26363.1 - 7.6e-40 137.1 2.0 8.6e-40 136.9 2.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK26363.1 - 8.2e-08 31.6 19.8 8.2e-08 31.6 19.8 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily BatA PF07584.11 CRK26363.1 - 1.2 9.6 3.9 17 5.9 0.8 3.3 3 0 0 3 3 3 0 Aerotolerance regulator N-terminal DUF2070 PF09843.9 CRK26363.1 - 1.8 6.8 7.2 2.2 6.5 7.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) CAS_CSE1 PF03378.15 CRK26364.1 - 6.1e-162 539.1 1.1 8e-162 538.7 0.1 1.7 3 0 0 3 3 3 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 CRK26364.1 - 3.2e-152 506.6 7.0 5e-152 506.0 7.0 1.3 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.19 CRK26364.1 - 2.3e-13 49.8 0.8 1.1e-12 47.6 0.1 2.7 3 0 0 3 3 3 1 Importin-beta N-terminal domain V-ATPase_H_N PF03224.14 CRK26364.1 - 0.0012 18.2 7.3 0.0047 16.3 0.0 3.6 3 2 1 4 4 4 1 V-ATPase subunit H Phyto_Pns9_10 PF05878.11 CRK26364.1 - 0.013 14.7 1.5 0.083 12.0 1.5 2.1 1 1 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 DUF1529 PF07485.11 CRK26364.1 - 0.017 15.0 0.0 6.4 6.7 0.0 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1259) DUF3384 PF11864.8 CRK26365.1 - 6.8e-143 477.0 0.5 3e-142 474.9 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.15 CRK26365.1 - 1.5e-53 181.1 0.0 3.6e-53 179.9 0.0 1.7 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.16 CRK26365.1 - 1.1e-39 136.6 3.5 3e-35 122.0 0.9 3.0 3 0 0 3 3 3 2 Tuberin DUF3361 PF11841.8 CRK26365.1 - 8.6e-05 22.5 0.3 0.0013 18.7 0.0 3.0 4 0 0 4 4 4 1 Domain of unknown function (DUF3361) CBP_BcsO PF17037.5 CRK26365.1 - 6.1 7.0 6.5 39 4.3 0.2 3.4 3 0 0 3 3 3 0 Cellulose biosynthesis protein BcsO Acetyltransf_1 PF00583.25 CRK26366.1 - 0.00017 21.8 0.0 0.00051 20.2 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CRK26366.1 - 0.00034 21.0 0.0 0.00073 19.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CRK26366.1 - 0.0013 18.7 0.0 0.0024 17.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CRK26366.1 - 0.015 15.3 0.1 0.043 13.8 0.0 1.7 2 0 0 2 2 2 0 FR47-like protein Acetyltransf_13 PF13880.6 CRK26366.1 - 0.064 13.3 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_9 PF13527.7 CRK26366.1 - 0.075 13.1 0.1 0.38 10.8 0.0 2.2 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain DUF3759 PF12585.8 CRK26369.1 - 2.3e-23 82.0 1.3 3.1e-23 81.6 1.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) EF-hand_7 PF13499.6 CRK26369.1 - 0.0014 19.0 1.1 0.0033 17.8 0.2 2.0 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 CRK26369.1 - 0.0029 17.4 0.1 0.0081 16.0 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 CRK26369.1 - 0.013 14.9 2.7 0.014 14.9 0.8 1.9 2 0 0 2 2 2 0 EF hand GP46 PF07409.12 CRK26372.1 - 0.14 11.9 0.0 0.17 11.7 0.0 1.1 1 0 0 1 1 1 0 Phage protein GP46 HD_3 PF13023.6 CRK26374.1 - 5.2e-40 137.1 0.2 6.6e-40 136.7 0.2 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 CRK26374.1 - 2.3e-08 34.0 0.0 4.5e-08 33.1 0.0 1.4 1 1 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 CRK26374.1 - 0.024 14.8 0.3 0.072 13.3 0.3 1.8 1 1 0 1 1 1 0 HD domain HLH PF00010.26 CRK26375.1 - 8.2e-16 57.7 0.1 1.5e-15 56.9 0.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain ZapB PF06005.12 CRK26375.1 - 0.03 14.8 4.3 0.089 13.3 4.3 1.7 1 0 0 1 1 1 0 Cell division protein ZapB KxDL PF10241.9 CRK26375.1 - 0.067 13.5 0.6 0.17 12.2 0.6 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein DUF4164 PF13747.6 CRK26375.1 - 0.074 13.3 2.9 0.14 12.4 2.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) YabA PF06156.13 CRK26375.1 - 0.12 13.0 0.4 0.23 12.1 0.4 1.4 1 0 0 1 1 1 0 Initiation control protein YabA DivIC PF04977.15 CRK26375.1 - 0.92 9.3 3.2 2.3 8.1 3.2 1.7 1 0 0 1 1 1 0 Septum formation initiator Pkinase PF00069.25 CRK26378.1 - 9.5e-40 136.6 0.1 6.3e-22 78.2 0.2 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CRK26378.1 - 1.1e-13 51.1 0.3 2.3e-09 36.9 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 CRK26378.1 - 0.036 12.8 0.7 0.067 12.0 0.7 1.5 1 1 0 1 1 1 0 Fungal protein kinase SPX PF03105.19 CRK26378.1 - 3.3 7.5 16.7 1.4 8.7 3.6 2.1 2 0 0 2 2 2 0 SPX domain Med26 PF08711.11 CRK26379.1 - 9.5e-08 32.0 0.0 2.1e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Umbravirus_LDM PF04817.12 CRK26379.1 - 0.041 13.2 5.9 0.073 12.4 5.9 1.4 1 0 0 1 1 1 0 Umbravirus long distance movement (LDM) family Brr6_like_C_C PF10104.9 CRK26380.1 - 2.2e-33 114.9 0.4 2.7e-33 114.5 0.4 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Pex16 PF08610.10 CRK26381.1 - 4e-140 466.6 0.1 4.5e-140 466.4 0.1 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) DUF4681 PF15732.5 CRK26382.1 - 0.009 16.3 0.6 0.009 16.3 0.6 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4681) zf-C2H2_4 PF13894.6 CRK26384.1 - 0.0018 18.9 17.2 0.048 14.5 1.8 4.1 3 0 0 3 3 3 2 C2H2-type zinc finger CAC1F_C PF16885.5 CRK26384.1 - 0.24 11.1 10.5 0.5 10.0 10.5 1.5 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term TFIIA PF03153.13 CRK26384.1 - 0.45 10.5 31.6 0.022 14.8 25.8 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SopE_GEF PF07487.13 CRK26384.1 - 0.61 10.2 5.0 1 9.5 5.0 1.3 1 0 0 1 1 1 0 SopE GEF domain zf-C2H2 PF00096.26 CRK26384.1 - 2.8 8.6 15.7 0.34 11.4 1.1 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type PIEZO PF15917.5 CRK26384.1 - 7.3 6.0 18.1 12 5.3 18.1 1.2 1 0 0 1 1 1 0 Piezo Exonuc_VII_L PF02601.15 CRK26384.1 - 8.3 5.9 11.2 13 5.2 11.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit zf-met PF12874.7 CRK26384.1 - 8.5 6.9 14.4 0.93 10.0 0.6 3.5 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Lin-8 PF03353.15 CRK26384.1 - 9.3 5.7 20.2 16 4.9 20.2 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist RNA_pol_Rpa2_4 PF06883.12 CRK26387.1 - 2.9e-24 84.8 0.0 4.2e-24 84.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain tRNA-synt_2 PF00152.20 CRK26388.1 - 1.8e-73 247.4 0.0 2.7e-73 246.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.9 CRK26388.1 - 4.8e-17 61.9 0.1 8.1e-17 61.2 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) tRNA_anti-codon PF01336.25 CRK26388.1 - 6.5e-08 32.4 0.0 1.3e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CRK26388.1 - 0.043 13.3 0.4 5.3 6.4 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Abhydrolase_3 PF07859.13 CRK26389.1 - 1.2e-42 146.2 0.0 1.8e-42 145.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CRK26389.1 - 7.1e-07 28.9 0.0 0.0087 15.6 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.28 CRK26389.1 - 7.5e-05 21.8 0.0 0.00024 20.1 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_2 PF02230.16 CRK26389.1 - 0.07 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 CRK26389.1 - 0.15 12.6 7.5 0.038 14.6 3.9 1.7 1 1 1 2 2 2 0 Alpha/beta hydrolase family Sec7 PF01369.20 CRK26390.1 - 2.4e-26 92.5 0.0 4.6e-26 91.6 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 CRK26390.1 - 2.7e-18 66.5 0.1 6.3e-18 65.3 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Glyco_hydro_16 PF00722.21 CRK26391.1 - 4.5e-42 143.5 0.3 7.5e-42 142.8 0.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF1524 PF07510.11 CRK26393.1 - 1.7e-06 28.0 0.0 2.2e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) HNH_4 PF13395.6 CRK26393.1 - 0.09 12.7 0.0 3.3 7.7 0.0 2.2 2 0 0 2 2 2 0 HNH endonuclease Sulfatase PF00884.23 CRK26395.1 - 3.6e-26 92.3 0.0 5.1e-26 91.8 0.0 1.2 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 CRK26395.1 - 6.1e-07 29.6 0.2 2.3e-06 27.8 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4976) DUF229 PF02995.17 CRK26395.1 - 3.2e-05 22.8 0.0 3.3e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Phosphodiest PF01663.22 CRK26395.1 - 0.093 12.3 0.0 0.19 11.3 0.0 1.5 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 CRK26397.1 - 0.0099 15.3 0.0 0.011 15.1 0.0 1.0 1 0 0 1 1 1 1 Sulfatase Sugar_tr PF00083.24 CRK26399.1 - 3.8e-62 210.6 21.0 1.3e-59 202.3 21.0 2.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK26399.1 - 5e-06 25.7 26.2 0.002 17.1 25.0 3.1 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 CRK26399.1 - 0.0013 17.2 1.0 0.0013 17.2 1.0 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF1304 PF06993.12 CRK26399.1 - 0.39 10.7 5.6 1.5 8.8 0.8 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1304) Fungal_trans PF04082.18 CRK26401.1 - 1.2e-11 44.2 0.0 1.5e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain NuiA PF07924.11 CRK26401.1 - 0.2 12.1 0.1 0.47 10.9 0.1 1.6 1 0 0 1 1 1 0 Nuclease A inhibitor-like protein Ctr PF04145.15 CRK26407.1 - 2.6e-19 70.3 0.1 3e-19 70.1 0.1 1.1 1 0 0 1 1 1 1 Ctr copper transporter family DUF4148 PF13663.6 CRK26407.1 - 0.094 12.9 0.1 0.23 11.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) PHO4 PF01384.20 CRK26410.1 - 2.3e-108 362.2 10.1 2.7e-108 362.0 10.1 1.0 1 0 0 1 1 1 1 Phosphate transporter family Cupin_1 PF00190.22 CRK26412.1 - 2.4e-05 24.0 0.2 3.3e-05 23.5 0.2 1.2 1 0 0 1 1 1 1 Cupin RestrictionSfiI PF11487.8 CRK26412.1 - 0.1 12.5 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Type II restriction enzyme SfiI MFS_1 PF07690.16 CRK26414.1 - 2.6e-24 85.8 13.2 9.5e-21 74.1 13.2 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily ABC_membrane PF00664.23 CRK26416.1 - 2.6e-38 132.2 14.6 3.4e-38 131.9 14.6 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 CRK26416.1 - 1.7e-34 119.3 0.0 3.1e-34 118.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 CRK26416.1 - 2.9e-06 27.8 0.0 6.4e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 CRK26416.1 - 1.8e-05 24.3 0.0 0.0026 17.2 0.0 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 CRK26416.1 - 9.8e-05 22.6 0.0 0.00067 19.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 CRK26416.1 - 0.0006 19.7 0.2 0.033 14.0 0.0 2.3 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_14 PF13173.6 CRK26416.1 - 0.0015 18.6 0.0 0.013 15.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 CRK26416.1 - 0.0016 18.5 0.0 0.0045 17.1 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CRK26416.1 - 0.0018 18.2 0.0 0.0037 17.2 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA PF00004.29 CRK26416.1 - 0.0084 16.5 0.0 0.067 13.6 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 CRK26416.1 - 0.02 14.5 0.0 0.067 12.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CRK26416.1 - 0.024 14.8 0.1 0.073 13.2 0.0 1.9 2 0 0 2 2 1 0 AAA domain Zeta_toxin PF06414.12 CRK26416.1 - 0.026 13.8 0.0 0.077 12.3 0.0 1.8 2 0 0 2 2 1 0 Zeta toxin AAA_29 PF13555.6 CRK26416.1 - 0.026 14.2 0.0 0.083 12.6 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.6 CRK26416.1 - 0.047 13.9 0.0 0.14 12.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain Ras PF00071.22 CRK26416.1 - 0.051 13.2 0.1 0.15 11.7 0.0 1.8 2 0 0 2 2 2 0 Ras family AAA_7 PF12775.7 CRK26416.1 - 0.054 13.0 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Septin PF00735.18 CRK26416.1 - 0.063 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Septin SbcCD_C PF13558.6 CRK26416.1 - 0.065 13.5 0.4 1.3 9.3 0.4 2.6 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit NACHT PF05729.12 CRK26416.1 - 0.08 12.9 0.3 0.52 10.2 0.0 2.3 3 0 0 3 3 2 0 NACHT domain AAA_18 PF13238.6 CRK26416.1 - 0.083 13.4 0.0 0.25 11.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.15 CRK26416.1 - 0.085 12.8 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain DUF815 PF05673.13 CRK26416.1 - 0.087 12.0 0.0 0.17 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_30 PF13604.6 CRK26416.1 - 0.089 12.5 0.0 0.52 10.0 0.0 2.1 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.6 CRK26416.1 - 0.11 12.2 0.0 0.29 10.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CRK26416.1 - 0.17 12.3 0.0 0.43 11.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_15 PF13175.6 CRK26416.1 - 0.21 11.3 0.0 0.35 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Methyltransf_23 PF13489.6 CRK26419.1 - 4.9e-10 39.5 0.0 7.6e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK26419.1 - 3.1e-08 34.2 0.0 4.6e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CRK26419.1 - 8.1e-08 32.8 0.0 1.3e-07 32.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK26419.1 - 2.2e-05 25.1 0.0 3.9e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CRK26419.1 - 0.0016 17.8 0.0 0.0021 17.4 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 CRK26419.1 - 0.002 18.0 0.0 0.0029 17.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.12 CRK26419.1 - 0.016 15.0 0.0 0.022 14.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_9 PF08003.11 CRK26419.1 - 0.073 12.0 0.0 0.1 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Zn_clus PF00172.18 CRK26420.1 - 1.3e-08 34.8 14.1 2.1e-08 34.2 14.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain APG5 PF04106.12 CRK26421.1 - 8.2e-42 143.3 0.0 3.4e-41 141.3 0.0 1.7 1 1 0 1 1 1 1 Autophagy protein Apg5 YpzI PF14140.6 CRK26422.1 - 1.4 8.7 17.2 20 5.1 0.1 5.4 5 0 0 5 5 5 0 YpzI-like protein MARVEL PF01284.23 CRK26425.1 - 3.6e-17 62.7 15.8 4.4e-17 62.4 15.8 1.1 1 0 0 1 1 1 1 Membrane-associating domain ABC2_membrane_5 PF13346.6 CRK26425.1 - 0.039 13.5 9.4 0.051 13.1 9.4 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF4149 PF13664.6 CRK26425.1 - 0.077 13.3 3.7 0.53 10.6 0.8 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) Pox_A14 PF05767.12 CRK26425.1 - 0.27 11.4 4.0 0.67 10.2 0.2 2.2 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 Zn_peptidase_2 PF04298.12 CRK26425.1 - 0.83 9.0 6.2 0.11 11.9 2.6 1.4 2 0 0 2 2 2 0 Putative neutral zinc metallopeptidase SNF2_N PF00176.23 CRK26426.1 - 1.8e-101 339.4 0.2 3.7e-47 160.7 0.0 3.2 3 0 0 3 3 3 3 SNF2 family N-terminal domain VIGSSK PF14773.6 CRK26426.1 - 2.2e-26 91.7 1.4 5.6e-26 90.4 1.4 1.8 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.31 CRK26426.1 - 1.9e-18 66.8 0.0 9.4e-18 64.6 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CRK26426.1 - 1.1e-16 61.3 0.0 5.3e-06 26.5 0.0 4.1 4 0 0 4 4 4 3 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CRK26426.1 - 2e-07 30.5 0.0 3.7e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase PFO_beta_C PF12367.8 CRK26426.1 - 0.0014 18.7 0.1 3.4 7.9 0.0 2.8 2 0 0 2 2 2 2 Pyruvate ferredoxin oxidoreductase beta subunit C terminal AAA_34 PF13872.6 CRK26426.1 - 0.0058 15.6 9.0 0.52 9.1 0.7 3.7 2 1 0 3 3 3 2 P-loop containing NTP hydrolase pore-1 Hydrolase_like PF13242.6 CRK26426.1 - 0.11 12.5 0.1 29 4.8 0.0 2.6 2 0 0 2 2 2 0 HAD-hyrolase-like ArfGap PF01412.18 CRK26427.1 - 1.1e-39 135.2 5.4 1e-23 83.6 0.0 3.8 2 1 1 3 3 3 2 Putative GTPase activating protein for Arf SNF2_N PF00176.23 CRK26427.1 - 1e-24 87.0 0.0 1.7e-24 86.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain UBA PF00627.31 CRK26427.1 - 9.2e-07 28.6 0.0 0.045 13.7 0.0 3.1 3 0 0 3 3 3 2 UBA/TS-N domain HOIP-UBA PF16678.5 CRK26427.1 - 0.00067 19.7 0.4 1.4 9.0 0.0 2.5 2 0 0 2 2 2 2 HOIP UBA domain pair CUE PF02845.16 CRK26427.1 - 0.051 13.3 0.1 16 5.3 0.0 2.7 2 0 0 2 2 2 0 CUE domain YscJ_FliF PF01514.17 CRK26427.1 - 0.056 13.1 0.1 10 5.7 0.0 2.4 2 0 0 2 2 2 0 Secretory protein of YscJ/FliF family IQCJ-SCHIP1 PF15157.6 CRK26427.1 - 0.17 11.7 4.7 3.7 7.4 0.3 2.7 2 0 0 2 2 2 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif AAA_34 PF13872.6 CRK26427.1 - 0.24 10.3 0.6 0.53 9.1 0.6 1.5 1 1 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 Oxysterol_BP PF01237.18 CRK26428.1 - 7.5e-19 67.8 1.3 1e-18 67.3 1.3 1.2 1 0 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 CRK26428.1 - 9.7e-09 35.4 1.4 3.9e-08 33.5 0.1 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain GOLD_2 PF13897.6 CRK26428.1 - 0.03 14.8 0.4 0.055 14.0 0.0 1.6 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking Oxysterol_BP PF01237.18 CRK26429.1 - 2.5e-175 582.8 0.3 7.9e-100 334.3 0.0 3.8 2 1 1 3 3 3 3 Oxysterol-binding protein PH_8 PF15409.6 CRK26429.1 - 1.7e-36 124.4 1.1 3.1e-36 123.5 0.1 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 CRK26429.1 - 1.6e-05 25.4 0.0 5.7e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 PH domain gpW PF02831.15 CRK26429.1 - 0.00014 21.7 0.0 35 4.4 0.0 4.6 4 0 0 4 4 4 0 gpW DUF150_C PF17384.2 CRK26429.1 - 0.23 11.6 1.9 27 5.0 0.1 2.7 2 0 0 2 2 2 0 RimP C-terminal SH3 domain GEN1_C PF18380.1 CRK26429.1 - 1.7 9.6 12.5 3.1 8.7 0.6 3.1 3 0 0 3 3 3 0 Holliday junction resolvase Gen1 C-terminal domain betaPIX_CC PF16523.5 CRK26429.1 - 5.7 6.8 8.1 26 4.7 0.9 3.0 2 0 0 2 2 2 0 betaPIX coiled coil Peptidase_M48 PF01435.18 CRK26430.1 - 7e-52 176.0 0.1 9.8e-35 120.1 0.0 2.3 2 0 0 2 2 2 2 Peptidase family M48 Methyltransf_23 PF13489.6 CRK26430.1 - 3e-42 144.3 0.0 4.6e-20 72.1 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 CRK26430.1 - 1.1e-20 74.1 0.0 9.7e-09 35.8 0.0 3.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 CRK26430.1 - 5.7e-14 52.2 0.0 2.8e-05 23.9 0.0 3.4 2 2 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 CRK26430.1 - 8.8e-12 45.5 0.0 0.00028 21.5 0.0 3.0 3 0 0 3 3 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 CRK26430.1 - 1.2e-07 32.4 0.0 0.036 14.8 0.0 3.2 2 1 0 2 2 2 2 Methyltransferase domain MTS PF05175.14 CRK26430.1 - 5.3e-06 26.1 0.0 0.12 11.9 0.0 2.6 2 2 0 2 2 2 2 Methyltransferase small domain Methyltransf_2 PF00891.18 CRK26430.1 - 1.6e-05 24.4 0.0 0.18 11.1 0.0 2.3 2 0 0 2 2 2 2 O-methyltransferase domain PrmA PF06325.13 CRK26430.1 - 7.6e-05 22.2 0.0 0.5 9.7 0.0 2.6 2 0 0 2 2 2 2 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 CRK26430.1 - 0.00035 20.1 0.0 1 8.8 0.0 2.4 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_16 PF10294.9 CRK26430.1 - 0.0082 15.9 0.0 3.8 7.2 0.0 2.2 2 0 0 2 2 2 2 Lysine methyltransferase Ubie_methyltran PF01209.18 CRK26430.1 - 0.01 15.2 0.0 4.1 6.7 0.0 2.7 2 2 0 2 2 2 0 ubiE/COQ5 methyltransferase family PCMT PF01135.19 CRK26430.1 - 0.052 13.3 0.0 17 5.1 0.0 2.8 2 2 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) YqjK PF13997.6 CRK26430.1 - 0.085 13.1 0.6 17 5.8 0.1 2.6 2 0 0 2 2 2 0 YqjK-like protein Tap-RNA_bind PF09162.10 CRK26430.1 - 0.096 12.5 0.1 23 4.9 0.0 2.3 2 0 0 2 2 2 0 Tap, RNA-binding SAM_Exu PF18609.1 CRK26430.1 - 0.32 11.1 4.3 9.2 6.4 0.1 3.4 4 0 0 4 4 4 0 Exuperantia SAM-like domain Cyt-b5 PF00173.28 CRK26431.1 - 2.6e-32 110.8 1.3 1.8e-20 72.8 0.1 2.1 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Nuclease_act PF08133.11 CRK26431.1 - 1.1e-05 25.3 0.3 0.47 10.7 0.0 3.1 3 0 0 3 3 3 2 Anticodon nuclease activator family DUF5034 PF16437.5 CRK26431.1 - 0.00013 21.9 0.0 0.42 10.6 0.0 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF5034) V-ATPase_H_C PF11698.8 CRK26431.1 - 0.0071 16.4 0.0 1.8 8.7 0.0 2.4 1 1 1 2 2 2 2 V-ATPase subunit H YonK PF09642.10 CRK26431.1 - 0.011 15.9 0.3 1.2e+02 2.9 0.0 4.1 2 2 2 4 4 4 0 YonK protein BRX PF08381.11 CRK26431.1 - 0.017 14.5 6.8 1 8.8 0.7 3.3 2 2 0 2 2 2 0 Transcription factor regulating root and shoot growth via Pin3 YqzH PF14164.6 CRK26431.1 - 0.054 13.6 1.0 0.29 11.2 0.1 2.5 3 0 0 3 3 3 0 YqzH-like protein SWIB PF02201.18 CRK26431.1 - 0.086 12.7 0.2 18 5.3 0.0 2.3 2 0 0 2 2 2 0 SWIB/MDM2 domain Urotensin_II PF02083.15 CRK26431.1 - 0.72 9.7 4.7 16 5.5 0.4 2.5 2 0 0 2 2 2 0 Urotensin II Kinesin PF00225.23 CRK26432.1 - 2.4e-110 368.6 0.0 2.4e-110 368.6 0.0 1.9 2 0 0 2 2 2 1 Kinesin motor domain Kinesin_assoc PF16183.5 CRK26432.1 - 3.4e-97 323.8 32.3 3.4e-30 105.5 0.2 7.0 4 3 3 7 7 7 4 Kinesin-associated DUF3694 PF12473.8 CRK26432.1 - 8.8e-29 101.1 1.4 1.9e-19 70.8 0.0 3.2 2 1 1 3 3 3 2 Kinesin protein Microtub_bd PF16796.5 CRK26432.1 - 1.2e-24 87.0 0.0 3e-24 85.6 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding Yop-YscD_cpl PF16697.5 CRK26432.1 - 6e-08 32.9 0.0 1.3 9.4 0.0 3.9 3 0 0 3 3 3 3 Inner membrane component of T3SS, cytoplasmic domain PH PF00169.29 CRK26432.1 - 6.6e-07 29.8 0.0 0.038 14.5 0.0 3.6 2 1 0 2 2 2 2 PH domain KIF1B PF12423.8 CRK26432.1 - 2.7e-06 27.7 0.4 2.7e-06 27.7 0.4 2.1 2 0 0 2 2 1 1 Kinesin protein 1B LptF_LptG PF03739.14 CRK26432.1 - 0.11 11.3 0.1 37 3.0 0.0 3.1 3 0 0 3 3 3 0 Lipopolysaccharide export system permease LptF/LptG FEZ PF07763.13 CRK26432.1 - 0.29 10.8 28.3 3.6 7.3 0.1 5.5 5 0 0 5 5 5 0 FEZ-like protein FeoC PF09012.10 CRK26432.1 - 1.4 9.0 3.3 1.6e+02 2.4 0.1 3.5 3 0 0 3 3 3 0 FeoC like transcriptional regulator DUF5320 PF17253.2 CRK26432.1 - 7.3 7.7 6.8 92 4.2 0.0 4.1 3 1 0 3 3 2 0 Family of unknown function (DUF5320) Peptidase_M1 PF01433.20 CRK26433.1 - 2.8e-42 144.8 0.3 3.9e-42 144.3 0.3 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 CRK26433.1 - 1.1e-39 135.0 0.0 1.9e-39 134.2 0.0 1.4 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 CRK26433.1 - 2e-31 109.6 0.2 3.6e-31 108.8 0.2 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Uds1 PF15456.6 CRK26434.1 - 3e-32 111.5 5.1 3e-32 111.5 5.1 2.3 2 0 0 2 2 2 1 Up-regulated During Septation T2SSF PF00482.23 CRK26434.1 - 0.034 14.1 1.3 0.17 11.9 0.5 2.1 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F Podoplanin PF05808.11 CRK26435.1 - 3.2e-05 24.1 4.3 3.2e-05 24.1 4.3 2.5 3 0 0 3 3 3 1 Podoplanin AJAP1_PANP_C PF15298.6 CRK26435.1 - 0.019 15.2 4.7 0.048 13.9 4.7 1.6 1 0 0 1 1 1 0 AJAP1/PANP C-terminus CFEM PF05730.11 CRK26435.1 - 0.06 13.4 5.1 0.11 12.6 5.1 1.5 1 0 0 1 1 1 0 CFEM domain DEAD PF00270.29 CRK26436.1 - 1.7e-34 119.1 0.0 5.8e-34 117.4 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CRK26436.1 - 4.1e-25 88.3 0.0 1.2e-24 86.8 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CRK26436.1 - 4.9e-06 26.7 0.0 1.1e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 CRK26436.1 - 0.00014 21.6 0.0 0.00032 20.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CRK26436.1 - 0.0046 17.3 0.0 0.096 13.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain PrpR_N PF06506.11 CRK26436.1 - 0.055 13.1 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Propionate catabolism activator FCH PF00611.23 CRK26437.1 - 2.1e-26 92.0 1.5 3.7e-26 91.2 0.1 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.6 CRK26437.1 - 2.1e-22 78.7 0.4 1.7e-12 47.0 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain C1_1 PF00130.22 CRK26437.1 - 1.4e-14 53.7 4.8 2.2e-14 53.0 4.8 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_1 PF00018.28 CRK26437.1 - 3.5e-14 52.1 0.1 1.8e-06 27.4 0.0 2.4 2 0 0 2 2 2 2 SH3 domain SH3_3 PF08239.11 CRK26437.1 - 0.00068 19.9 0.1 0.15 12.4 0.1 2.7 2 0 0 2 2 2 1 Bacterial SH3 domain C1_2 PF03107.16 CRK26437.1 - 0.0079 16.5 4.3 0.014 15.7 4.3 1.4 1 0 0 1 1 1 1 C1 domain SH3_2 PF07653.17 CRK26437.1 - 0.015 14.9 0.1 1.6 8.5 0.0 2.5 2 0 0 2 2 2 0 Variant SH3 domain SH3_10 PF17902.1 CRK26437.1 - 0.019 15.0 0.0 5.5 7.1 0.0 3.2 2 0 0 2 2 2 0 SH3 domain FYVE PF01363.21 CRK26437.1 - 0.26 11.4 3.2 0.53 10.5 3.2 1.4 1 0 0 1 1 1 0 FYVE zinc finger DUF4337 PF14235.6 CRK26437.1 - 0.63 10.1 4.6 2 8.5 4.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF2362 PF10154.9 CRK26437.1 - 0.9 8.4 7.1 1.3 7.8 7.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) Glyco_hydro_72 PF03198.14 CRK26438.1 - 2.7e-47 161.6 0.3 1.9e-29 102.9 0.9 2.1 1 1 1 2 2 2 2 Glucanosyltransferase Herpes_pp85 PF04637.12 CRK26438.1 - 0.022 13.2 0.0 0.032 12.7 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Cellulase PF00150.18 CRK26438.1 - 0.07 12.6 0.0 0.091 12.2 0.0 1.2 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) MRI PF15325.6 CRK26438.1 - 0.47 11.6 2.5 0.62 11.2 0.5 2.1 2 0 0 2 2 2 0 Modulator of retrovirus infection MFS_1 PF07690.16 CRK26439.1 - 4e-06 26.0 16.6 0.00098 18.1 14.1 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily ECH_1 PF00378.20 CRK26440.1 - 5.1e-38 130.8 0.1 1.2e-37 129.6 0.1 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CRK26440.1 - 3.8e-33 115.4 0.0 7.4e-29 101.3 0.0 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase PEP_hydrolase PF09370.10 CRK26440.1 - 0.011 15.0 0.2 0.018 14.3 0.2 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate hydrolase-like DUF2188 PF09954.9 CRK26440.1 - 0.084 13.0 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2188) Tfb5 PF06331.12 CRK26441.1 - 2.8e-26 91.3 0.8 3.3e-26 91.1 0.8 1.1 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Ran_BP1 PF00638.18 CRK26442.1 - 4.5e-12 46.3 0.0 1.3e-11 44.9 0.0 1.7 1 1 0 1 1 1 1 RanBP1 domain Nucleoporin_FG PF13634.6 CRK26442.1 - 2.4e-05 25.1 57.9 0.00054 20.7 25.2 11.0 3 2 6 9 9 9 5 Nucleoporin FG repeat region K_oxygenase PF13434.6 CRK26443.1 - 2.1e-07 30.4 0.0 0.0054 15.9 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 CRK26443.1 - 8.6e-05 21.9 0.1 0.27 10.4 0.0 2.6 2 2 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CRK26443.1 - 0.0002 20.7 0.0 0.0075 15.6 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 CRK26443.1 - 0.011 15.7 0.2 0.064 13.2 0.1 2.2 2 1 1 3 3 3 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 CRK26443.1 - 0.025 14.8 0.1 0.4 11.0 0.0 2.8 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 CRK26443.1 - 0.036 13.3 0.0 0.17 11.1 0.1 2.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CRK26443.1 - 0.043 12.9 0.0 0.072 12.1 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 CRK26443.1 - 0.051 12.8 0.0 0.093 12.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family DAO PF01266.24 CRK26443.1 - 0.093 12.3 0.6 1.6 8.2 0.1 2.8 3 1 0 3 3 3 0 FAD dependent oxidoreductase CTP_transf_like PF01467.26 CRK26444.1 - 5.8e-29 101.1 0.0 9e-29 100.5 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like CLZ PF16526.5 CRK26446.1 - 0.031 14.6 0.6 0.096 13.1 0.6 1.8 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Pex24p PF06398.11 CRK26446.1 - 0.13 11.2 0.1 0.19 10.7 0.1 1.3 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin MDM10 PF12519.8 CRK26447.1 - 3.2e-147 491.2 0.4 1.2e-114 383.8 1.6 2.0 1 1 1 2 2 2 2 Mitochondrial distribution and morphology protein 10 Ribosomal_S19e PF01090.19 CRK26448.1 - 1.7e-57 192.9 0.1 3.2e-57 192.0 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S19e Git3 PF11710.8 CRK26448.1 - 1.4e-19 70.7 8.1 2.5e-19 69.8 8.1 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 zf-C2H2 PF00096.26 CRK26448.1 - 4.2e-06 26.9 11.3 0.015 15.7 0.8 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type Dicty_CAR PF05462.11 CRK26448.1 - 4.8e-05 22.7 1.9 0.0019 17.4 2.2 2.1 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor zf-C2H2_4 PF13894.6 CRK26448.1 - 0.0012 19.5 7.9 0.58 11.1 2.2 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger GPR_Gpa2_C PF11970.8 CRK26448.1 - 0.015 15.4 0.0 0.015 15.4 0.0 2.4 3 0 0 3 3 3 0 G protein-coupled glucose receptor regulating Gpa2 C-term CbiQ PF02361.16 CRK26448.1 - 0.054 13.1 4.4 0.11 12.1 4.4 1.4 1 0 0 1 1 1 0 Cobalt transport protein CBM_1 PF00734.18 CRK26449.1 - 3.5e-11 42.9 6.0 3.5e-11 42.9 6.0 2.0 2 0 0 2 2 2 1 Fungal cellulose binding domain BUD22 PF09073.10 CRK26449.1 - 0.0046 16.4 20.3 0.0059 16.0 20.3 1.0 1 0 0 1 1 1 1 BUD22 DUF2457 PF10446.9 CRK26449.1 - 0.48 9.5 22.6 0.64 9.1 22.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) UCR_hinge PF02320.16 CRK26449.1 - 1.5 9.1 4.1 2.5 8.4 4.1 1.3 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein Glyco_transf_90 PF05686.12 CRK26450.1 - 2.3e-05 23.5 0.0 0.055 12.4 0.0 2.9 3 0 0 3 3 3 2 Glycosyl transferase family 90 Glyco_transf_90 PF05686.12 CRK26454.1 - 0.00023 20.2 0.0 0.15 10.9 0.0 2.8 3 0 0 3 3 3 2 Glycosyl transferase family 90 Trypan_PARP PF05887.11 CRK26454.1 - 3.5 7.6 9.5 0.58 10.1 4.2 2.2 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Fungal_trans PF04082.18 CRK26455.1 - 3.2e-52 177.2 0.0 2.7e-25 88.9 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain HEPPP_synt_1 PF07307.11 CRK26455.1 - 0.098 12.2 0.6 15 5.1 0.1 2.3 2 0 0 2 2 2 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 DHquinase_I PF01487.15 CRK26456.1 - 4e-46 158.1 0.0 5.4e-46 157.7 0.0 1.2 1 0 0 1 1 1 1 Type I 3-dehydroquinase Peptidase_S8 PF00082.22 CRK26458.1 - 7.8e-07 28.6 0.5 0.00016 21.1 0.5 2.3 1 1 0 1 1 1 1 Subtilase family MFS_1 PF07690.16 CRK26459.1 - 4.1e-34 118.1 54.0 4.2e-34 118.0 52.9 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK26459.1 - 2.9e-11 42.9 13.2 2.9e-11 42.9 13.2 2.4 1 1 0 2 2 2 1 Sugar (and other) transporter Oxidored_q6 PF01058.22 CRK26460.1 - 8.6e-16 58.0 0.1 1.5e-15 57.2 0.1 1.4 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit HECT PF00632.25 CRK26461.1 - 3.4e-79 266.5 0.0 3.4e-47 161.4 0.0 2.2 1 1 1 2 2 2 2 HECT-domain (ubiquitin-transferase) WW PF00397.26 CRK26461.1 - 3.9e-34 116.4 20.7 6.1e-13 48.6 6.3 3.6 3 0 0 3 3 3 3 WW domain C2 PF00168.30 CRK26461.1 - 5e-18 65.3 0.0 1.7e-17 63.6 0.0 1.9 1 0 0 1 1 1 1 C2 domain Rrn6 PF10214.9 CRK26461.1 - 0.011 14.3 4.7 0.014 13.9 4.7 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor RRM_1 PF00076.22 CRK26462.1 - 1.1e-16 60.4 0.0 1.7e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spc7 PF08317.11 CRK26462.1 - 0.013 14.5 2.3 0.015 14.2 2.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Nup35_RRM_2 PF14605.6 CRK26462.1 - 0.043 13.8 0.0 0.074 13.1 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF724 PF05266.14 CRK26462.1 - 0.097 12.5 3.3 0.13 12.0 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) RRM_occluded PF16842.5 CRK26462.1 - 0.14 12.1 0.0 0.26 11.2 0.0 1.5 1 1 0 1 1 1 0 Occluded RNA-recognition motif Ion_trans PF00520.31 CRK26463.1 - 2.2e-07 30.4 2.7 2.9e-07 30.0 2.7 1.2 1 0 0 1 1 1 1 Ion transport protein Zn_clus PF00172.18 CRK26465.1 - 6e-07 29.5 9.9 1e-06 28.8 9.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 CRK26465.1 - 1e-05 24.6 0.1 1.4e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF202 PF02656.15 CRK26466.1 - 1.5e-16 60.6 4.8 9e-16 58.1 3.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Tctex-1 PF03645.13 CRK26467.1 - 3.5e-37 126.8 0.0 4.1e-37 126.5 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family F-box-like PF12937.7 CRK26468.1 - 0.0018 18.1 0.0 0.0037 17.1 0.0 1.5 1 0 0 1 1 1 1 F-box-like Pex14_N PF04695.13 CRK26468.1 - 0.33 11.6 9.2 4.4 7.9 0.1 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region p450 PF00067.22 CRK26470.1 - 8.3e-53 179.8 0.0 4.1e-26 91.7 0.0 3.8 3 1 0 3 3 3 3 Cytochrome P450 Nucleocap_ssRNA PF11128.8 CRK26470.1 - 0.11 12.2 0.0 9 6.0 0.0 2.3 2 0 0 2 2 2 0 Plant viral coat protein nucleocapsid Phage_holin_3_7 PF05449.11 CRK26470.1 - 4.8 7.3 5.4 82 3.3 0.1 3.5 3 0 0 3 3 3 0 Putative 3TM holin, Phage_holin_3 Ceramidse_alk_C PF17048.5 CRK26471.1 - 3.5e-17 62.8 0.1 8.5e-17 61.5 0.0 1.6 2 0 0 2 2 2 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal Ceramidase_alk PF04734.13 CRK26471.1 - 1.8e-14 53.3 3.2 2.3e-14 53.0 3.2 1.1 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal CBM46 PF18448.1 CRK26471.1 - 0.13 12.6 0.0 0.19 12.1 0.0 1.4 1 1 0 1 1 1 0 Carbohydrate binding domain SBP56 PF05694.11 CRK26472.1 - 2.2e-06 26.8 0.0 0.0072 15.2 0.0 2.6 2 1 0 2 2 2 2 56kDa selenium binding protein (SBP56) Cupin_1 PF00190.22 CRK26473.1 - 5e-40 136.6 0.1 6.2e-19 68.1 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 CRK26473.1 - 2.5e-22 78.4 1.4 8.5e-12 44.6 0.1 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 CRK26473.1 - 0.00016 21.3 0.0 0.46 10.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 CRK26473.1 - 0.01 15.7 0.5 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 AraC-like ligand binding domain Cpn10 PF00166.21 CRK26473.1 - 0.13 12.3 0.0 2.5 8.2 0.0 2.3 2 0 0 2 2 2 0 Chaperonin 10 Kd subunit Gln-synt_N PF03951.19 CRK26474.1 - 7.9e-13 47.9 0.0 1.4e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain FYVE PF01363.21 CRK26477.1 - 0.0039 17.3 4.8 0.0039 17.3 4.8 2.0 2 0 0 2 2 2 1 FYVE zinc finger FYVE PF01363.21 CRK26478.1 - 0.011 15.8 5.3 0.011 15.8 5.3 2.7 3 0 0 3 3 3 0 FYVE zinc finger DUF3403 PF11883.8 CRK26478.1 - 0.17 12.0 1.3 0.35 11.0 1.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3403) MRP-L20 PF12824.7 CRK26480.1 - 1.9e-52 177.7 4.0 2.2e-52 177.5 4.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Neugrin PF06413.11 CRK26480.1 - 0.00031 20.8 0.0 0.00051 20.1 0.0 1.3 1 0 0 1 1 1 1 Neugrin LytB_WW PF18342.1 CRK26481.1 - 0.05 13.7 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 Endo-beta-N-acetylglucosaminidase LytB WW domain Not3 PF04065.15 CRK26482.1 - 1.3e-88 296.3 21.4 1.6e-88 296.1 21.4 1.1 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component Syntaxin_2 PF14523.6 CRK26482.1 - 0.0044 17.4 3.6 0.0044 17.4 3.6 2.1 2 0 0 2 2 2 1 Syntaxin-like protein HUN PF08729.10 CRK26482.1 - 0.19 11.7 5.8 0.5 10.4 5.8 1.8 1 1 0 1 1 1 0 HPC2 and ubinuclein domain Sec5 PF15469.6 CRK26482.1 - 0.63 9.8 8.0 0.11 12.4 1.8 2.1 2 0 0 2 2 2 0 Exocyst complex component Sec5 Cep57_MT_bd PF06657.13 CRK26482.1 - 1.8 9.1 7.9 1.6 9.2 2.9 2.6 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 T2SSM PF04612.12 CRK26482.1 - 3.2 7.8 8.7 1.4 9.0 1.9 2.9 1 1 2 3 3 3 0 Type II secretion system (T2SS), protein M DUF1192 PF06698.11 CRK26482.1 - 4.3 7.5 9.3 0.43 10.7 1.4 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF1192) Nnf1 PF03980.14 CRK26482.1 - 5.9 7.3 17.4 15 6.0 12.2 3.3 2 1 0 2 2 2 0 Nnf1 AMP-binding_C_2 PF14535.6 CRK26482.1 - 6 7.2 6.9 21 5.5 1.7 2.9 2 1 1 3 3 3 0 AMP-binding enzyme C-terminal domain Swi5 PF07061.11 CRK26482.1 - 6.3 7.0 14.4 8.1 6.6 0.5 3.2 2 1 1 3 3 3 0 Swi5 DUF4140 PF13600.6 CRK26482.1 - 7.5 7.1 6.7 11 6.5 0.8 2.7 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Pro_isomerase PF00160.21 CRK26483.1 - 7.1e-47 159.6 0.0 1e-46 159.1 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 CRK26483.1 - 0.0015 18.5 11.0 0.0053 16.8 0.3 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 CRK26483.1 - 0.045 13.6 0.7 0.14 12.0 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 CRK26483.1 - 0.07 13.3 2.7 0.19 11.9 2.7 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat RasGAP PF00616.19 CRK26484.1 - 1.5e-28 99.9 0.0 6.6e-19 68.4 0.0 3.2 1 1 2 3 3 3 2 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 CRK26484.1 - 9.8e-06 25.8 0.0 2.5e-05 24.5 0.0 1.7 1 1 0 1 1 1 1 C2 domain RasGAP PF00616.19 CRK26485.1 - 2.8e-28 99.1 0.0 8.4e-19 68.1 0.0 3.3 2 1 2 4 4 4 2 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 CRK26485.1 - 1.2e-05 25.5 0.0 2.9e-05 24.3 0.0 1.7 1 1 0 1 1 1 1 C2 domain SelP_N PF04592.14 CRK26485.1 - 1.8 7.9 5.7 3.3 7.0 5.7 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Pro_isomerase PF00160.21 CRK26486.1 - 5.8e-47 159.9 0.0 8.3e-47 159.4 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 CRK26486.1 - 0.00042 20.2 9.7 0.0032 17.4 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 CRK26486.1 - 0.024 14.4 0.4 0.093 12.6 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Not3 PF04065.15 CRK26487.1 - 2.4e-87 292.2 21.4 2.4e-87 292.2 21.4 2.0 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 CRK26487.1 - 1.6e-42 144.7 5.6 1.6e-42 144.7 5.6 2.0 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family Syntaxin_2 PF14523.6 CRK26487.1 - 0.0047 17.3 3.4 0.02 15.3 3.4 2.0 1 0 0 1 1 1 1 Syntaxin-like protein DUF2373 PF10180.9 CRK26487.1 - 0.022 14.6 2.4 0.059 13.2 2.4 1.7 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) zf-C2H2 PF00096.26 CRK26487.1 - 0.23 12.0 9.7 0.072 13.6 1.3 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type Iso_dh PF00180.20 CRK26488.1 - 1.3e-42 146.2 0.0 1.8e-42 145.7 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase UPF0160 PF03690.13 CRK26489.1 - 8e-130 433.1 0.0 9e-130 432.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Endosulfine PF04667.17 CRK26490.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 cAMP-regulated phosphoprotein/endosulfine conserved region UTP15_C PF09384.10 CRK26491.1 - 7.2e-43 145.8 0.0 9.9e-34 116.1 0.0 2.2 2 0 0 2 2 2 2 UTP15 C terminal WD40 PF00400.32 CRK26491.1 - 1.2e-10 41.8 0.1 0.00018 22.2 0.0 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK26491.1 - 0.0092 16.3 0.0 0.043 14.1 0.0 2.1 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Pinin_SDK_memA PF04696.13 CRK26491.1 - 0.81 9.8 3.8 0.71 9.9 2.8 1.4 1 1 0 1 1 1 0 pinin/SDK/memA/ protein conserved region C2 PF00168.30 CRK26492.1 - 8.6e-17 61.3 0.0 1.4e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 C2 domain SIS PF01380.22 CRK26493.1 - 6.4e-11 42.2 0.0 1.7e-10 40.8 0.0 1.8 1 0 0 1 1 1 1 SIS domain CBS PF00571.28 CRK26493.1 - 0.04 14.4 1.0 0.69 10.4 1.0 2.6 1 1 0 1 1 1 0 CBS domain Ribonuclease PF00545.20 CRK26495.1 - 7.9e-06 26.5 0.5 1.6e-05 25.6 0.0 1.7 2 0 0 2 2 2 1 ribonuclease DUF2076 PF09849.9 CRK26495.1 - 0.13 12.3 3.5 0.18 11.8 3.5 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) RAP1 PF07218.11 CRK26495.1 - 2.1 6.5 12.0 2.8 6.1 12.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Macoilin PF09726.9 CRK26495.1 - 3.3 6.2 5.7 4 5.9 5.7 1.1 1 0 0 1 1 1 0 Macoilin family Secretin_N_2 PF07655.13 CRK26495.1 - 3.9 8.1 18.3 7.6 7.2 18.3 1.6 1 0 0 1 1 1 0 Secretin N-terminal domain Proteasome PF00227.26 CRK26496.1 - 6.2e-49 166.1 0.0 8.9e-49 165.6 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CRK26496.1 - 1.1e-13 50.6 0.3 2.1e-13 49.6 0.3 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Secretogranin_V PF05281.11 CRK26497.1 - 0.041 13.5 0.0 0.06 13.0 0.0 1.2 1 0 0 1 1 1 0 Neuroendocrine protein 7B2 precursor (Secretogranin V) TMEM234 PF10639.9 CRK26498.1 - 5.8e-36 123.1 0.3 7.3e-36 122.7 0.3 1.1 1 0 0 1 1 1 1 Putative transmembrane family 234 EamA PF00892.20 CRK26498.1 - 9.8e-05 22.5 4.2 0.038 14.2 3.2 2.2 2 0 0 2 2 2 2 EamA-like transporter family DUF1211 PF06736.11 CRK26498.1 - 0.031 14.7 0.0 1.1 9.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1211) DUF485 PF04341.12 CRK26498.1 - 0.068 13.1 0.4 1.5 8.8 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function, DUF485 Rubella_Capsid PF05750.11 CRK26498.1 - 0.17 11.5 0.0 0.2 11.2 0.0 1.1 1 0 0 1 1 1 0 Rubella capsid protein Con-6 PF10346.9 CRK26499.1 - 1.1e-32 111.7 5.3 1.9e-17 63.0 0.2 2.2 2 0 0 2 2 2 2 Conidiation protein 6 DUF1542 PF07564.11 CRK26499.1 - 0.013 15.6 3.0 1.1 9.4 0.0 2.3 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1542) SpoIIIAH PF12685.7 CRK26499.1 - 0.44 10.3 9.1 4.7 7.0 9.1 2.2 1 1 0 1 1 1 0 SpoIIIAH-like protein RNA_Me_trans PF04252.13 CRK26500.1 - 3.9e-81 271.4 0.0 4.4e-81 271.2 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Peptidase_S10 PF00450.22 CRK26501.1 - 1.5e-91 307.9 0.1 1.8e-91 307.7 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Mpp10 PF04006.12 CRK26502.1 - 4.6e-86 289.6 44.7 7.9e-86 288.9 44.7 1.3 1 0 0 1 1 1 1 Mpp10 protein DRE2_N PF16803.5 CRK26502.1 - 5e-15 55.9 0.0 1.1e-14 54.8 0.0 1.5 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus Fructosamin_kin PF03881.14 CRK26502.1 - 5.3e-09 35.7 0.0 9e-09 34.9 0.0 1.3 1 0 0 1 1 1 1 Fructosamine kinase CAP_N PF01213.19 CRK26502.1 - 0.0014 18.2 1.2 0.0048 16.4 1.2 1.9 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal SPX PF03105.19 CRK26503.1 - 2.7e-14 53.9 7.2 4.3e-06 26.9 0.0 3.9 2 1 2 4 4 4 3 SPX domain CcmD PF04995.14 CRK26503.1 - 0.095 12.8 0.2 0.44 10.7 0.2 2.2 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Acetyltransf_1 PF00583.25 CRK26504.1 - 3.5e-08 33.7 0.0 9.5e-08 32.3 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CRK26504.1 - 2.4e-06 27.9 0.0 4.3e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CRK26504.1 - 5.4e-06 26.4 0.0 9.6e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CRK26504.1 - 0.011 15.7 0.0 0.022 14.7 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_9 PF13527.7 CRK26504.1 - 0.031 14.4 0.0 0.46 10.6 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CRK26504.1 - 0.056 13.6 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase TMEM151 PF14857.6 CRK26505.1 - 0.09 11.7 0.3 0.21 10.5 0.3 1.5 1 0 0 1 1 1 0 TMEM151 family SHNi-TPR PF10516.9 CRK26507.1 - 1.1e-13 50.4 3.6 2.5e-13 49.2 0.1 3.2 3 0 0 3 3 3 1 SHNi-TPR TPR_12 PF13424.6 CRK26507.1 - 0.0023 18.2 5.0 0.0054 17.0 0.3 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 CRK26507.1 - 0.012 15.9 0.2 0.071 13.5 0.0 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 CRK26507.1 - 0.039 14.6 2.1 0.039 14.6 2.1 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 CRK26507.1 - 0.41 11.6 5.5 0.7 10.9 1.5 3.3 2 1 0 2 2 2 0 Tetratricopeptide repeat Acetyltransf_11 PF13720.6 CRK26507.1 - 0.52 10.8 2.2 0.9 10.0 0.1 2.4 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 TPR_2 PF07719.17 CRK26507.1 - 0.69 10.2 8.5 1.1 9.6 1.6 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 CRK26507.1 - 3.4 7.4 7.0 77 3.1 0.0 3.7 4 0 0 4 4 4 0 TPR repeat TMPIT PF07851.13 CRK26507.1 - 8.2 5.6 5.9 4.1 6.6 0.9 2.3 2 0 0 2 2 2 0 TMPIT-like protein LETM1 PF07766.13 CRK26509.1 - 4.2e-08 32.9 0.2 1.4e-07 31.2 0.0 1.8 2 0 0 2 2 2 1 LETM1-like protein GATase_6 PF13522.6 CRK26511.1 - 1.1e-12 48.3 0.0 2.3e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 CRK26511.1 - 1.5e-09 37.8 0.0 2.8e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 CRK26511.1 - 3.8e-07 29.8 0.1 7.2e-07 28.9 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Clathrin PF00637.20 CRK26529.1 - 2.4e-20 72.9 2.4 2.4e-20 72.9 2.4 4.0 5 1 0 5 5 5 1 Region in Clathrin and VPS BUD22 PF09073.10 CRK26529.1 - 0.00014 21.3 11.6 0.00014 21.3 11.6 1.8 2 0 0 2 2 2 1 BUD22 NBP1 PF08537.10 CRK26529.1 - 0.00057 19.4 1.1 0.0014 18.2 1.1 1.6 1 0 0 1 1 1 1 Fungal Nap binding protein NBP1 YafQ_toxin PF15738.5 CRK26529.1 - 0.019 15.3 0.4 12 6.2 0.0 2.7 2 0 0 2 2 2 0 Bacterial toxin of type II toxin-antitoxin system, YafQ DNA_pol_phi PF04931.13 CRK26529.1 - 0.019 13.1 35.1 0.029 12.5 35.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi Mpp10 PF04006.12 CRK26529.1 - 0.024 13.1 21.3 0.05 12.1 21.3 1.4 1 0 0 1 1 1 0 Mpp10 protein Vps39_1 PF10366.9 CRK26529.1 - 0.031 14.6 0.2 0.15 12.3 0.2 2.2 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 Nop14 PF04147.12 CRK26529.1 - 0.23 9.6 33.2 0.43 8.7 33.2 1.3 1 0 0 1 1 1 0 Nop14-like family RAB3GAP2_C PF14656.6 CRK26529.1 - 0.25 9.5 0.8 0.41 8.8 0.8 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus DUF913 PF06025.12 CRK26529.1 - 1.1 8.2 6.6 2.2 7.2 6.6 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Sigma70_ner PF04546.13 CRK26529.1 - 1.5 8.7 26.6 3.4 7.5 23.3 3.1 3 0 0 3 3 3 0 Sigma-70, non-essential region SDA1 PF05285.12 CRK26529.1 - 2.2 7.6 31.4 0.16 11.4 25.9 1.8 2 0 0 2 2 2 0 SDA1 SAPS PF04499.15 CRK26529.1 - 3.3 6.4 11.6 5.7 5.6 11.6 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TRAP_alpha PF03896.16 CRK26529.1 - 6.9 5.8 15.5 15 4.7 15.5 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RPN2_C PF18004.1 CRK26529.1 - 7.6 6.4 17.3 3.7 7.4 13.6 2.2 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain ANAPC1 PF12859.7 CRK26531.1 - 1.4e-40 138.8 0.2 4.4e-40 137.2 0.2 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 CRK26531.1 - 0.026 15.0 1.0 39 4.9 0.1 4.5 4 0 0 4 4 4 0 Proteasome/cyclosome repeat eIF3_N PF09440.10 CRK26532.1 - 2.2e-44 151.1 2.4 4.2e-44 150.2 2.4 1.5 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 CRK26532.1 - 0.0097 16.4 0.0 0.092 13.3 0.0 2.5 2 1 0 2 2 2 1 PCI domain RPN7 PF10602.9 CRK26532.1 - 0.025 14.3 0.3 0.067 12.9 0.1 1.8 1 1 0 1 1 1 0 26S proteasome subunit RPN7 Caprin-1_dimer PF18293.1 CRK26532.1 - 0.038 14.5 0.7 0.11 13.0 0.2 2.0 2 0 0 2 2 2 0 Caprin-1 dimerization domain MRP-S31 PF15433.6 CRK26532.1 - 0.14 11.8 2.7 1.5 8.4 2.7 2.1 1 1 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Img2 PF05046.14 CRK26533.1 - 5.1e-20 71.6 0.0 8.4e-20 70.9 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) ARID PF01388.21 CRK26534.1 - 1.9e-17 63.7 2.4 2.7e-17 63.2 0.0 2.5 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain EVE PF01878.18 CRK26535.1 - 4.1e-19 69.0 0.0 2e-18 66.8 0.0 1.9 2 0 0 2 2 2 1 EVE domain Basic PF01586.16 CRK26535.1 - 0.0047 18.1 0.1 0.0097 17.1 0.1 1.5 1 0 0 1 1 1 1 Myogenic Basic domain U3_assoc_6 PF08640.11 CRK26536.1 - 1.5e-27 95.4 1.7 9.7e-26 89.7 0.2 2.5 1 1 1 2 2 2 2 U3 small nucleolar RNA-associated protein 6 NRDE-2 PF08424.10 CRK26536.1 - 3.2e-05 23.2 1.2 9e-05 21.7 1.4 1.6 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 CRK26536.1 - 0.16 12.9 2.4 45 5.2 0.1 3.6 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 CRK26536.1 - 0.27 11.4 3.2 4.5 7.5 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Frag1 PF10277.9 CRK26537.1 - 2.5e-39 135.1 8.6 2.5e-39 135.1 8.6 3.1 3 0 0 3 3 3 2 Frag1/DRAM/Sfk1 family Exo_endo_phos PF03372.23 CRK26537.1 - 0.0085 15.6 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family p450 PF00067.22 CRK26538.1 - 1.2e-58 199.0 0.0 1.6e-58 198.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Nucleoporin_FG PF13634.6 CRK26539.1 - 6e-06 27.0 138.7 0.11 13.3 26.2 6.6 1 1 4 5 5 5 3 Nucleoporin FG repeat region Ribosomal_S10 PF00338.22 CRK26540.1 - 1.7e-26 92.3 0.2 2.2e-26 91.9 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Fibrillarin_2 PF10113.9 CRK26540.1 - 0.0087 14.7 0.0 0.01 14.5 0.0 1.1 1 0 0 1 1 1 1 Fibrillarin-like archaeal protein CUE PF02845.16 CRK26541.1 - 5.1e-07 29.3 0.0 1e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 CUE domain OGFr_III PF04680.13 CRK26541.1 - 0.17 12.5 1.4 17 6.2 0.3 2.9 2 0 0 2 2 2 0 Opioid growth factor receptor repeat FXMRP1_C_core PF12235.8 CRK26541.1 - 9.4 6.9 16.1 1.4 9.6 10.8 2.3 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal Fungal_trans_2 PF11951.8 CRK26542.1 - 3.6e-33 114.9 0.0 4.9e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Gti1_Pac2 PF09729.9 CRK26545.1 - 1.7e-43 148.8 5.3 1.7e-37 129.2 0.1 2.6 2 1 1 3 3 3 2 Gti1/Pac2 family tRNA-synt_2 PF00152.20 CRK26546.1 - 4.1e-78 262.6 0.0 5.1e-78 262.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 CRK26546.1 - 0.051 13.1 0.2 1.5 8.2 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.25 CRK26546.1 - 0.053 13.5 0.0 0.088 12.8 0.0 1.4 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain DUF2263 PF10021.9 CRK26547.1 - 0.00015 22.2 0.0 0.035 14.5 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2263) FA_hydroxylase PF04116.13 CRK26551.1 - 5.1e-09 36.6 1.2 6.2e-09 36.3 1.2 1.0 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily Brix PF04427.18 CRK26553.1 - 1.2e-47 162.5 0.0 1.5e-47 162.2 0.0 1.1 1 0 0 1 1 1 1 Brix domain DUF1168 PF06658.12 CRK26553.1 - 1.3 8.8 15.7 0.055 13.3 9.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) PPP4R2 PF09184.11 CRK26553.1 - 7.4 6.1 14.6 12 5.3 14.6 1.3 1 0 0 1 1 1 0 PPP4R2 DEAD PF00270.29 CRK26554.1 - 4.1e-50 170.0 0.0 6.1e-50 169.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CRK26554.1 - 8.3e-33 113.0 0.1 8.8e-32 109.8 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CRK26554.1 - 5.9e-05 23.1 0.0 0.0001 22.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CRK26554.1 - 0.13 12.6 0.0 0.37 11.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain Sporozoite_P67 PF05642.11 CRK26555.1 - 0.04 12.0 5.0 0.05 11.7 5.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen MFS_1 PF07690.16 CRK26556.1 - 2.8e-07 29.8 0.4 3.2e-07 29.6 0.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK26556.1 - 0.015 14.2 0.0 0.016 14.1 0.0 1.1 1 0 0 1 1 1 0 Sugar (and other) transporter NAR2 PF16974.5 CRK26557.1 - 0.19 11.1 0.0 0.3 10.5 0.0 1.2 1 0 0 1 1 1 0 High-affinity nitrate transporter accessory ADH_zinc_N_2 PF13602.6 CRK26558.1 - 2e-23 83.9 0.0 3.6e-23 83.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 CRK26558.1 - 1.1e-14 54.6 0.0 2e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CRK26558.1 - 0.0006 19.7 0.8 0.0034 17.2 0.0 2.4 2 2 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain CUE PF02845.16 CRK26559.1 - 2.3e-05 24.0 0.0 3.8e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 CUE domain DUF3697 PF12478.8 CRK26559.1 - 0.0018 18.3 0.0 0.0051 16.9 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-associated protein 2 FMO-like PF00743.19 CRK26560.1 - 1.5e-33 116.1 0.0 1.2e-15 57.0 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 CRK26560.1 - 7.9e-21 74.6 0.1 1.1e-14 54.4 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CRK26560.1 - 9.4e-13 48.0 1.5 2.3e-08 33.6 0.1 2.7 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 CRK26560.1 - 5.8e-12 45.4 0.0 9.9e-06 25.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CRK26560.1 - 4e-10 39.8 0.1 8.6e-06 25.6 0.0 2.9 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 CRK26560.1 - 1.9e-08 34.5 2.8 6.6e-08 32.7 0.7 3.0 3 1 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 CRK26560.1 - 3.9e-08 33.4 0.0 1e-07 32.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 CRK26560.1 - 1.3e-05 25.7 1.0 0.00061 20.3 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 CRK26560.1 - 0.00011 21.7 0.0 0.0068 15.7 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 CRK26560.1 - 0.00011 21.1 0.2 0.0002 20.2 0.2 1.4 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 CRK26560.1 - 0.00027 20.3 0.2 0.00071 18.9 0.1 1.8 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 CRK26560.1 - 0.0011 18.4 0.2 0.0038 16.6 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Shikimate_DH PF01488.20 CRK26560.1 - 0.0027 17.8 0.0 0.0068 16.5 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 CRK26560.1 - 0.0037 16.4 0.0 0.011 14.9 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 CRK26560.1 - 0.014 14.8 1.0 0.018 14.4 0.1 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 CRK26560.1 - 0.067 12.3 0.5 0.11 11.5 0.5 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_2 PF03446.15 CRK26560.1 - 0.15 12.2 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Glu_dehyd_C PF16912.5 CRK26560.1 - 0.16 11.4 0.0 0.33 10.4 0.0 1.4 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Pectate_lyase PF03211.13 CRK26561.1 - 7.3e-65 218.3 1.3 9.5e-65 217.9 1.3 1.1 1 0 0 1 1 1 1 Pectate lyase Sulfotransfer_4 PF17784.1 CRK26562.1 - 3.8e-57 193.6 0.0 4.4e-57 193.4 0.0 1.0 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CRK26562.1 - 0.0075 16.7 0.1 0.051 14.0 0.0 2.1 1 1 1 2 2 2 1 Sulfotransferase family Glyco_hydro_43 PF04616.14 CRK26563.1 - 7.1e-59 199.5 3.3 9e-59 199.1 3.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 AbfB PF05270.13 CRK26563.1 - 4e-17 62.5 0.0 1.1e-16 61.1 0.0 1.7 1 1 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) domain Tudor_2 PF18104.1 CRK26563.1 - 0.11 12.2 0.3 0.49 10.1 0.3 2.0 2 0 0 2 2 2 0 Jumonji domain-containing protein 2A Tudor domain Peptidase_S28 PF05577.12 CRK26564.1 - 7.9e-51 173.2 0.0 3e-50 171.3 0.0 1.7 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Cu-oxidase_2 PF07731.14 CRK26566.1 - 4.1e-40 136.7 2.6 2.7e-38 130.8 0.2 2.4 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 CRK26566.1 - 2.5e-34 117.8 1.2 6.5e-34 116.5 1.2 1.7 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase PF00394.22 CRK26566.1 - 4.5e-08 33.4 1.2 0.0023 18.1 0.1 3.5 2 1 1 3 3 3 2 Multicopper oxidase GalKase_gal_bdg PF10509.9 CRK26567.1 - 2.8e-21 74.8 0.1 5.6e-21 73.8 0.1 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 CRK26567.1 - 6.6e-14 51.9 4.9 1.7e-13 50.5 3.3 2.4 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 CRK26567.1 - 3.8e-12 46.4 0.0 1.7e-11 44.3 0.0 2.1 2 0 0 2 2 2 1 GHMP kinases C terminal TFIIA PF03153.13 CRK26569.1 - 1.7 8.5 18.4 1.6 8.6 8.0 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit zf-C2H2 PF00096.26 CRK26569.1 - 2.2 8.9 12.5 0.57 10.7 1.6 3.2 3 0 0 3 3 3 0 Zinc finger, C2H2 type Thioredoxin PF00085.20 CRK26570.1 - 0.024 14.6 0.0 0.033 14.2 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin QSOX_Trx1 PF18108.1 CRK26570.1 - 0.15 12.3 0.0 0.18 12.0 0.0 1.2 1 0 0 1 1 1 0 QSOX Trx-like domain HyaE PF07449.11 CRK26570.1 - 0.18 11.8 0.0 0.25 11.3 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE DUF4485 PF14846.6 CRK26574.1 - 0.089 12.8 1.0 5.9 7.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4485) Catalase-rel PF06628.12 CRK26578.1 - 1.8e-09 37.7 0.0 2.5e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Catalase-related immune-responsive Exo_endo_phos_2 PF14529.6 CRK26579.1 - 9.8e-06 25.4 0.6 3e-05 23.8 0.0 2.2 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Baculo_p24 PF05073.12 CRK26579.1 - 0.013 15.3 1.5 0.023 14.5 1.5 1.4 1 0 0 1 1 1 0 Baculovirus P24 capsid protein USP8_interact PF08941.10 CRK26579.1 - 0.059 13.2 1.7 0.14 12.0 1.7 1.6 1 0 0 1 1 1 0 USP8 interacting Laminin_II PF06009.12 CRK26579.1 - 0.18 11.8 4.7 0.61 10.1 4.7 2.0 1 0 0 1 1 1 0 Laminin Domain II KxDL PF10241.9 CRK26579.1 - 0.23 11.8 12.3 2.2 8.6 9.8 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein SlyX PF04102.12 CRK26579.1 - 0.53 10.9 14.5 2.2 9.0 14.5 2.1 1 0 0 1 1 1 0 SlyX TMPIT PF07851.13 CRK26579.1 - 0.79 8.9 4.1 1.1 8.4 4.1 1.3 1 0 0 1 1 1 0 TMPIT-like protein DUF4763 PF15960.5 CRK26579.1 - 1 8.6 11.1 2.3 7.5 11.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) HAUS-augmin3 PF14932.6 CRK26579.1 - 1.9 8.0 11.2 0.27 10.8 6.5 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 DUF1690 PF07956.11 CRK26579.1 - 3 8.3 10.6 19 5.7 0.1 3.0 3 0 0 3 3 3 0 Protein of Unknown function (DUF1690) EMC3_TMCO1 PF01956.16 CRK26579.1 - 4.5 7.0 5.7 7.6 6.2 5.7 1.4 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Pkinase PF00069.25 CRK26581.1 - 5.6e-12 45.6 0.0 7.6e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 CRK26581.1 - 2.7e-06 26.9 0.0 3.9e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 CRK26581.1 - 3.6e-06 26.5 0.0 5e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CRK26581.1 - 9.6e-05 22.4 1.0 0.0012 18.9 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CRK26582.1 - 5e-136 453.7 0.0 6.2e-136 453.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 CRK26582.1 - 8.6e-05 22.0 0.0 0.0002 20.8 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 CRK26582.1 - 0.04 13.8 0.0 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 CRK26582.1 - 0.19 11.0 0.0 0.36 10.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RhoGEF67_u2 PF16614.5 CRK26583.1 - 0.12 12.5 0.1 0.29 11.2 0.1 1.6 1 0 0 1 1 1 0 Unstructured region two on RhoGEF 6 and 7 DUF1843 PF08898.10 CRK26584.1 - 0.011 16.3 0.6 0.02 15.4 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) DUF503 PF04456.12 CRK26584.1 - 0.096 12.6 0.2 0.16 11.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF503) YebO PF13974.6 CRK26584.1 - 0.11 12.6 0.9 0.2 11.7 0.9 1.4 1 0 0 1 1 1 0 YebO-like protein Pan3_PK PF18101.1 CRK26589.1 - 0.084 12.8 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Pan3 Pseudokinase domain PQQ PF01011.21 CRK26592.1 - 0.00031 20.5 1.0 2.2 8.4 0.0 3.6 3 0 0 3 3 3 2 PQQ enzyme repeat PQQ_3 PF13570.6 CRK26592.1 - 0.0055 17.2 5.3 0.064 13.8 0.3 4.3 4 1 0 4 4 4 1 PQQ-like domain PQQ_2 PF13360.6 CRK26592.1 - 0.012 15.2 0.0 0.41 10.2 0.0 2.3 2 0 0 2 2 2 0 PQQ-like domain Abhydrolase_3 PF07859.13 CRK26593.1 - 1.2e-52 178.9 0.0 1.4e-52 178.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 CRK26593.1 - 5.4e-05 22.2 0.0 0.00012 21.1 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 CRK26593.1 - 9.7e-05 21.9 0.0 0.0029 17.1 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 CRK26593.1 - 0.002 17.1 0.0 0.0026 16.7 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 CRK26593.1 - 0.0022 17.3 0.0 0.0035 16.7 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CRK26593.1 - 0.0035 18.0 3.2 0.0052 17.4 3.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.12 CRK26593.1 - 0.059 12.0 0.0 0.19 10.3 0.0 1.7 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.16 CRK26593.1 - 0.068 13.0 0.0 0.15 11.8 0.0 1.5 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase GMC_oxred_N PF00732.19 CRK26595.1 - 3.2e-35 121.9 0.0 6.1e-35 121.0 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CRK26595.1 - 2.2e-21 76.9 0.5 3.9e-21 76.1 0.5 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 CRK26595.1 - 1.3e-09 37.6 0.0 0.001 18.3 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 CRK26595.1 - 1.5e-09 37.9 0.5 0.00032 20.4 0.1 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 CRK26595.1 - 1.6e-08 33.7 0.1 1.5e-05 23.9 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.14 CRK26595.1 - 9.2e-07 28.4 0.1 7.1e-05 22.2 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CRK26595.1 - 2.1e-05 24.7 0.0 5.1e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 CRK26595.1 - 0.00012 21.2 0.1 0.0002 20.5 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.7 CRK26595.1 - 0.00036 20.0 0.0 0.0047 16.3 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 CRK26595.1 - 0.00072 18.9 0.8 0.0077 15.5 0.3 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CRK26595.1 - 0.0017 17.7 0.1 0.0032 16.8 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 CRK26595.1 - 0.003 18.1 0.2 0.2 12.3 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CRK26595.1 - 0.0056 15.8 0.1 0.028 13.5 0.1 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 CRK26595.1 - 0.0095 15.2 0.0 0.05 12.8 0.0 2.0 2 0 0 2 2 2 1 Thi4 family Trp_halogenase PF04820.14 CRK26595.1 - 0.014 14.3 0.1 0.066 12.0 0.1 1.9 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_9 PF13454.6 CRK26595.1 - 0.097 12.7 0.4 0.39 10.7 0.2 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Beta-lactamase PF00144.24 CRK26596.1 - 3.9e-48 164.4 0.0 5.5e-48 163.9 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.20 CRK26596.1 - 0.063 12.7 0.0 0.095 12.1 0.0 1.2 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase Fungal_trans PF04082.18 CRK26598.1 - 2.2e-30 105.6 0.0 3.3e-30 105.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK26598.1 - 8.7e-07 29.0 7.6 1.5e-06 28.2 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L37ae PF01780.19 CRK26598.1 - 0.13 12.4 5.5 0.27 11.3 5.5 1.5 1 0 0 1 1 1 0 Ribosomal L37ae protein family MaoC_dehydrat_N PF13452.6 CRK26599.1 - 0.0015 18.7 0.0 0.0049 17.0 0.0 1.8 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase Sugar_tr PF00083.24 CRK26601.1 - 4.2e-40 138.0 17.5 2.1e-27 96.1 0.6 4.1 1 1 3 4 4 4 4 Sugar (and other) transporter MFS_1 PF07690.16 CRK26601.1 - 3.9e-09 35.9 24.6 4.9e-05 22.4 15.6 2.7 1 1 2 3 3 3 3 Major Facilitator Superfamily DUF1648 PF07853.11 CRK26601.1 - 0.022 14.4 0.9 1.3 8.7 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1648) OppC_N PF12911.7 CRK26601.1 - 0.61 10.1 0.0 0.61 10.1 0.0 2.6 2 1 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C HATPase_c PF02518.26 CRK26603.1 - 4.4e-26 91.6 0.1 9.8e-26 90.5 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Cytochrom_B561 PF03188.16 CRK26604.1 - 2.7e-17 63.2 7.3 4.6e-17 62.4 7.3 1.3 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2306 PF10067.9 CRK26604.1 - 0.0085 16.3 1.4 0.0085 16.3 1.4 2.8 1 1 1 3 3 3 1 Predicted membrane protein (DUF2306) DUF588 PF04535.12 CRK26604.1 - 0.071 12.9 3.1 0.12 12.2 2.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF588) DUF4006 PF13179.6 CRK26604.1 - 0.1 12.5 0.1 0.1 12.5 0.1 3.1 4 0 0 4 4 4 0 Family of unknown function (DUF4006) DUF4271 PF14093.6 CRK26604.1 - 0.15 12.0 5.0 0.038 13.9 1.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4271) DUF4079 PF13301.6 CRK26604.1 - 2 8.6 19.8 0.84 9.8 1.3 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF4079) MARVEL PF01284.23 CRK26604.1 - 3.1 7.8 11.8 6.4 6.8 9.0 2.5 1 1 1 2 2 2 0 Membrane-associating domain BPD_transp_2 PF02653.16 CRK26604.1 - 7.4 5.6 15.8 6.9 5.7 12.0 2.0 1 1 1 2 2 2 0 Branched-chain amino acid transport system / permease component Allantoicase PF03561.15 CRK26605.1 - 4e-93 309.0 0.1 8.3e-47 158.8 0.0 2.1 2 0 0 2 2 2 2 Allantoicase repeat Polysacc_deac_1 PF01522.21 CRK26617.1 - 2.6e-05 24.1 0.0 2.9e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2846 PF11008.8 CRK26617.1 - 0.097 12.7 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2846) Alk_phosphatase PF00245.20 CRK26625.1 - 1.6e-50 172.3 0.0 2e-50 172.0 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase FAD_binding_3 PF01494.19 CRK26626.1 - 7.9e-16 58.2 0.0 1.1e-15 57.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 CRK26626.1 - 7.6e-08 31.8 0.2 0.0025 16.9 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_3 PF13738.6 CRK26626.1 - 8.3e-06 25.3 0.1 0.00025 20.4 0.3 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CRK26626.1 - 1.2e-05 25.1 0.2 2.2e-05 24.2 0.1 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CRK26626.1 - 1.6e-05 25.0 0.1 6.2e-05 23.2 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 CRK26626.1 - 6.8e-05 22.3 0.0 0.0055 16.1 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 CRK26626.1 - 0.00025 20.4 0.1 0.0012 18.1 0.0 1.7 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CRK26626.1 - 0.00056 20.4 0.1 0.008 16.7 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 CRK26626.1 - 0.0032 16.4 1.2 0.11 11.3 0.4 2.1 1 1 0 2 2 2 1 Tryptophan halogenase FAD_binding_2 PF00890.24 CRK26626.1 - 0.012 14.7 0.2 0.025 13.7 0.2 1.5 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.21 CRK26626.1 - 0.021 14.1 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 CRK26626.1 - 0.022 13.5 0.2 0.036 12.8 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.17 CRK26626.1 - 0.027 13.7 0.3 0.11 11.7 0.1 1.9 2 0 0 2 2 2 0 Thi4 family GIDA PF01134.22 CRK26626.1 - 0.064 12.3 0.2 1.4 7.9 0.2 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A TrkA_N PF02254.18 CRK26626.1 - 0.074 13.3 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain XdhC_C PF13478.6 CRK26626.1 - 0.19 12.2 0.0 0.28 11.7 0.0 1.3 1 0 0 1 1 1 0 XdhC Rossmann domain 2TM PF13239.6 CRK26628.1 - 0.39 11.1 0.2 0.39 11.1 0.2 2.0 2 1 0 2 2 2 0 2TM domain DUF4131 PF13567.6 CRK26628.1 - 7.2 6.2 10.6 0.65 9.6 0.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Homeobox_KN PF05920.11 CRK26629.1 - 5.6e-11 42.2 0.3 1.9e-10 40.5 0.2 2.0 2 0 0 2 2 2 1 Homeobox KN domain HTH_Tnp_Tc5 PF03221.16 CRK26629.1 - 2.3e-05 24.3 0.1 0.00075 19.5 0.1 2.8 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain Homeodomain PF00046.29 CRK26629.1 - 0.0031 17.3 0.1 0.0091 15.8 0.1 1.8 1 0 0 1 1 1 1 Homeodomain zf-C2H2_4 PF13894.6 CRK26629.1 - 0.11 13.4 18.6 0.2 12.6 3.3 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2 PF00096.26 CRK26629.1 - 0.13 12.8 19.2 0.7 10.5 3.3 4.2 4 0 0 4 4 4 0 Zinc finger, C2H2 type SPX PF03105.19 CRK26629.1 - 1.4 8.7 5.9 2.2 8.1 5.9 1.2 1 0 0 1 1 1 0 SPX domain zf-met PF12874.7 CRK26629.1 - 4.6 7.8 7.9 15 6.1 0.0 3.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type AAA_12 PF13087.6 CRK26630.1 - 5.1e-20 72.0 0.0 1.5e-19 70.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain U-box PF04564.15 CRK26630.1 - 1.2e-17 63.8 0.0 2.7e-17 62.7 0.0 1.6 1 0 0 1 1 1 1 U-box domain HET PF06985.11 CRK26630.1 - 3.4e-09 37.2 4.8 3.2e-07 30.8 0.2 2.9 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) TPR_2 PF07719.17 CRK26630.1 - 0.00043 20.2 9.4 0.55 10.5 0.1 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat AAA_11 PF13086.6 CRK26630.1 - 0.00069 19.5 0.5 0.0011 18.8 0.0 1.5 2 0 0 2 2 1 1 AAA domain UvrD_C_2 PF13538.6 CRK26630.1 - 0.0054 16.5 0.3 0.09 12.6 0.0 2.6 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 CRK26630.1 - 0.0092 16.3 0.3 0.022 15.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain TPR_11 PF13414.6 CRK26630.1 - 0.0093 15.6 3.8 0.15 11.7 0.3 2.9 3 0 0 3 3 3 1 TPR repeat Helicase_RecD PF05127.14 CRK26630.1 - 0.016 15.1 0.0 0.043 13.7 0.0 1.7 1 0 0 1 1 1 0 Helicase ImpA_N PF06812.12 CRK26630.1 - 0.021 15.0 0.4 0.12 12.5 0.1 2.5 2 0 0 2 2 2 0 ImpA, N-terminal, type VI secretion system AAA_30 PF13604.6 CRK26630.1 - 0.029 14.1 0.0 0.074 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain CHIP_TPR_N PF18391.1 CRK26630.1 - 0.033 15.0 6.1 0.081 13.7 6.1 1.7 1 0 0 1 1 1 0 CHIP N-terminal tetratricopeptide repeat domain TPR_17 PF13431.6 CRK26630.1 - 0.2 12.1 4.7 2.8 8.5 0.3 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 CRK26630.1 - 0.25 12.3 2.9 5.5 8.1 0.5 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 CRK26630.1 - 0.31 11.0 9.2 6 6.9 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 CRK26630.1 - 2.7 8.6 8.2 2.9 8.5 1.7 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat Pox_Ag35 PF03286.14 CRK26631.1 - 0.21 11.4 2.3 14 5.5 1.1 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Transp_cyt_pur PF02133.15 CRK26632.1 - 3e-78 263.6 19.8 4.8e-68 229.9 11.0 3.1 1 1 2 3 3 3 3 Permease for cytosine/purines, uracil, thiamine, allantoin EMP24_GP25L PF01105.24 CRK26635.1 - 1.4e-26 93.6 0.1 1.5e-26 93.4 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF4686 PF15742.5 CRK26635.1 - 0.023 13.8 0.3 0.026 13.7 0.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4686) EzrA PF06160.12 CRK26635.1 - 0.056 11.6 0.8 0.067 11.4 0.8 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA adh_short_C2 PF13561.6 CRK26638.1 - 1.7e-50 171.7 5.4 3.1e-50 170.9 5.4 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ABC2_membrane PF01061.24 CRK26638.1 - 2.4e-42 144.7 36.2 5.8e-21 74.9 6.6 3.9 3 1 1 4 4 4 3 ABC-2 type transporter adh_short PF00106.25 CRK26638.1 - 1.4e-37 129.1 0.7 2.5e-37 128.2 0.7 1.3 1 0 0 1 1 1 1 short chain dehydrogenase ABC_tran PF00005.27 CRK26638.1 - 1.8e-35 122.4 0.0 2.3e-16 60.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 CRK26638.1 - 2.7e-28 97.7 1.4 1.8e-24 85.4 0.0 3.0 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 CRK26638.1 - 5.3e-18 65.4 0.1 2.2e-17 63.4 0.1 2.2 1 0 0 1 1 1 1 ABC-transporter N-terminal KR PF08659.10 CRK26638.1 - 2.9e-11 43.6 0.9 5.8e-11 42.6 0.9 1.4 1 0 0 1 1 1 1 KR domain AAA_16 PF13191.6 CRK26638.1 - 6.7e-07 29.8 0.1 0.0083 16.5 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 CRK26638.1 - 1.4e-06 28.3 0.0 0.063 13.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 CRK26638.1 - 3.5e-06 27.2 1.2 0.033 14.3 0.0 3.3 4 0 0 4 4 3 2 AAA domain AAA_18 PF13238.6 CRK26638.1 - 5.7e-05 23.7 0.0 0.028 15.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CRK26638.1 - 0.00015 21.4 0.1 0.014 15.1 0.1 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CRK26638.1 - 0.00031 20.7 0.0 0.0037 17.2 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_17 PF13207.6 CRK26638.1 - 0.00039 20.9 0.2 0.32 11.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain Epimerase PF01370.21 CRK26638.1 - 0.0011 18.5 0.2 0.0048 16.4 0.1 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family AAA_22 PF13401.6 CRK26638.1 - 0.0021 18.4 0.2 0.24 11.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 CRK26638.1 - 0.0024 17.5 0.1 0.049 13.2 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 CRK26638.1 - 0.0045 17.2 0.1 0.17 12.1 0.0 2.9 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 CRK26638.1 - 0.009 15.5 0.0 0.55 9.6 0.0 2.8 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain cobW PF02492.19 CRK26638.1 - 0.031 13.9 2.9 0.74 9.4 0.2 2.7 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain ATP-synt_ab PF00006.25 CRK26638.1 - 0.1 12.2 0.0 0.62 9.7 0.0 2.4 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_23 PF13476.6 CRK26638.1 - 0.11 13.0 0.3 0.49 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 CRK26638.1 - 0.15 12.5 0.3 17 5.8 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 CRK26638.1 - 0.15 12.1 0.3 8 6.5 0.1 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 CRK26638.1 - 0.22 11.4 6.2 3.8 7.4 0.0 2.7 3 0 0 3 3 2 0 NACHT domain DUF3073 PF11273.8 CRK26638.1 - 0.24 12.1 1.3 0.69 10.7 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3073) MMR_HSR1 PF01926.23 CRK26638.1 - 0.28 11.3 0.9 21 5.2 0.2 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_24 PF13479.6 CRK26638.1 - 0.29 10.8 0.9 16 5.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 CRK26638.1 - 2.3 8.5 4.5 6.8 7.0 0.0 2.8 3 0 0 3 3 2 0 AAA domain AAA_30 PF13604.6 CRK26638.1 - 2.8 7.6 8.2 2 8.1 0.2 2.9 3 0 0 3 3 2 0 AAA domain Cutinase PF01083.22 CRK26640.1 - 1.7e-47 161.7 0.0 2.2e-47 161.3 0.0 1.1 1 0 0 1 1 1 1 Cutinase VirJ PF06057.11 CRK26640.1 - 0.013 15.4 0.0 0.018 15.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) RraA-like PF03737.15 CRK26640.1 - 0.054 13.7 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 Aldolase/RraA PE-PPE PF08237.11 CRK26640.1 - 0.057 13.0 0.0 0.08 12.5 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain RRM_1 PF00076.22 CRK26642.1 - 4.2e-09 36.1 0.1 1.4e-08 34.4 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CRK26642.1 - 2.2e-05 24.4 0.0 4.5e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 CRK26642.1 - 0.0082 16.0 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_3 PF08777.11 CRK26642.1 - 0.031 14.3 0.1 0.068 13.2 0.1 1.6 1 0 0 1 1 1 0 RNA binding motif Amino_oxidase PF01593.24 CRK26644.1 - 3.5e-39 135.3 0.0 7.4e-39 134.3 0.0 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CRK26644.1 - 2.7e-06 27.5 0.1 1.3e-05 25.3 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain ANAPC15 PF15243.6 CRK26645.1 - 0.018 15.4 0.2 0.068 13.6 0.2 2.0 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 DUF4611 PF15387.6 CRK26645.1 - 0.029 14.6 2.5 0.062 13.5 0.5 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4611) FlaC_arch PF05377.11 CRK26645.1 - 0.54 10.7 7.1 0.62 10.5 0.2 4.0 4 1 1 5 5 5 0 Flagella accessory protein C (FlaC) DUF3496 PF12001.8 CRK26645.1 - 0.59 10.5 8.4 0.3 11.5 2.6 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF3496) DUF3584 PF12128.8 CRK26645.1 - 1.1 6.7 23.8 0.16 9.4 19.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) LETM1 PF07766.13 CRK26645.1 - 7.2 5.9 7.6 1.2 8.4 3.1 1.8 1 1 1 2 2 2 0 LETM1-like protein Prominin PF05478.11 CRK26645.1 - 7.4 4.4 13.2 13 3.6 13.2 1.4 1 1 0 1 1 1 0 Prominin KxDL PF10241.9 CRK26645.1 - 7.7 6.9 15.7 33 4.9 0.1 3.6 1 1 1 3 3 3 0 Uncharacterized conserved protein TssO PF17561.2 CRK26645.1 - 8.2 6.5 7.0 24 5.0 2.0 3.0 3 0 0 3 3 3 0 Type VI secretion system, TssO Zn_clus PF00172.18 CRK26646.1 - 8.4e-08 32.2 9.0 1.4e-07 31.5 9.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Nucleotid_trans PF03407.16 CRK26647.1 - 0.008 16.2 1.0 0.015 15.3 1.0 1.4 1 1 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Glyco_transf_34 PF05637.12 CRK26648.1 - 6.8e-08 32.5 1.8 1.2e-07 31.8 1.8 1.4 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Nucleotid_trans PF03407.16 CRK26648.1 - 0.00037 20.5 4.1 0.00041 20.4 1.5 2.1 1 1 1 2 2 2 1 Nucleotide-diphospho-sugar transferase FAD_binding_3 PF01494.19 CRK26649.1 - 9e-26 90.9 0.0 1.2e-25 90.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 CRK26649.1 - 1.6e-08 34.5 5.3 0.00016 21.4 4.4 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CRK26649.1 - 2.5e-08 33.5 1.8 0.00014 21.2 0.9 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CRK26649.1 - 1.2e-05 25.5 1.0 3.4e-05 24.0 1.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CRK26649.1 - 1.9e-05 23.9 2.1 4.1e-05 22.8 2.1 1.5 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 CRK26649.1 - 3.6e-05 23.0 1.5 0.00013 21.2 1.5 1.8 1 1 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 CRK26649.1 - 0.002 17.4 0.4 0.0037 16.5 0.4 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 CRK26649.1 - 0.0028 16.4 2.6 0.015 14.0 0.6 2.0 2 0 0 2 2 2 1 HI0933-like protein Trp_halogenase PF04820.14 CRK26649.1 - 0.0036 16.2 6.3 0.3 9.9 0.0 2.4 2 1 1 3 3 3 2 Tryptophan halogenase Pyr_redox_3 PF13738.6 CRK26649.1 - 0.0069 15.7 1.2 0.023 14.0 1.4 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CRK26649.1 - 0.007 16.4 0.1 0.013 15.5 0.1 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 CRK26649.1 - 0.0076 16.8 3.2 0.021 15.4 2.6 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 CRK26649.1 - 0.018 14.1 0.0 0.029 13.4 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase GIDA PF01134.22 CRK26649.1 - 0.039 13.0 1.5 0.062 12.4 0.9 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 CRK26649.1 - 0.14 11.5 1.8 0.28 10.5 1.7 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase Rossmann-like PF10727.9 CRK26649.1 - 0.23 11.3 1.8 1.5 8.7 0.2 2.7 3 0 0 3 3 3 0 Rossmann-like domain Cyclase PF04199.13 CRK26650.1 - 7e-12 45.7 0.0 1.2e-11 45.0 0.0 1.4 2 0 0 2 2 2 1 Putative cyclase ABM PF03992.16 CRK26651.1 - 9.1e-06 25.7 0.0 2.1e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Spc24 PF08286.11 CRK26656.1 - 0.018 15.2 0.1 0.87 9.9 0.1 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 FA PF08736.11 CRK26656.1 - 3.4 7.8 6.1 3.9 7.6 1.7 2.3 2 0 0 2 2 2 0 FERM adjacent (FA) p450 PF00067.22 CRK26657.1 - 4e-53 180.8 0.0 5.2e-53 180.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_43 PF04616.14 CRK26658.1 - 8.1e-74 248.5 0.7 1e-73 248.2 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Sugar_tr PF00083.24 CRK26659.1 - 2.8e-11 42.9 5.0 3.6e-11 42.6 5.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK26659.1 - 0.0012 17.8 2.6 0.0014 17.7 2.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MarR PF01047.22 CRK26660.1 - 0.17 11.9 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 MarR family MFS_1 PF07690.16 CRK26661.1 - 4.6e-32 111.3 30.8 4.6e-32 111.3 30.8 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily GFO_IDH_MocA_C PF02894.17 CRK26662.1 - 1.6e-12 47.4 0.2 5.4e-12 45.7 0.2 1.9 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain Skp1_POZ PF03931.15 CRK26663.1 - 0.0032 17.6 0.1 0.0044 17.2 0.1 1.4 1 1 0 1 1 1 1 Skp1 family, tetramerisation domain Cutinase PF01083.22 CRK26664.1 - 5.2e-37 127.5 2.3 6.3e-37 127.3 2.3 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 CRK26664.1 - 0.0002 21.0 0.2 0.00039 20.1 0.2 1.6 1 1 0 1 1 1 1 PE-PPE domain Abhydrolase_3 PF07859.13 CRK26664.1 - 0.024 14.5 0.2 0.037 13.9 0.2 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 CRK26664.1 - 0.062 13.1 0.0 0.096 12.5 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Amidohydro_3 PF07969.11 CRK26665.1 - 5.5e-69 233.9 4.3 6.3e-69 233.7 4.3 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 CRK26665.1 - 4.3e-12 46.0 0.1 3.7e-09 36.3 0.0 2.5 2 1 0 2 2 2 2 Amidohydrolase family YdjC PF04794.12 CRK26665.1 - 0.16 11.9 0.0 0.37 10.7 0.0 1.6 1 0 0 1 1 1 0 YdjC-like protein Transp_cyt_pur PF02133.15 CRK26666.1 - 6.1e-69 232.9 41.4 7.6e-69 232.6 41.4 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Trs65 PF12735.7 CRK26671.1 - 1.2e-47 162.9 0.3 1.3e-47 162.8 0.3 1.0 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 DUF5572 PF17733.1 CRK26672.1 - 3.9e-10 39.4 0.0 1.1e-09 37.9 0.0 1.8 1 0 0 1 1 1 1 Family of unknown function (DUF5572) PP2C PF00481.21 CRK26673.1 - 9.5e-44 150.0 0.0 2.8e-43 148.4 0.0 1.7 2 0 0 2 2 2 1 Protein phosphatase 2C PUF PF00806.19 CRK26673.1 - 6.5e-39 129.5 0.3 3.4e-06 26.5 0.0 9.2 10 0 0 10 10 10 6 Pumilio-family RNA binding repeat MRP-S33 PF08293.11 CRK26673.1 - 1.2e-23 83.1 0.0 6.4e-23 80.8 0.0 2.3 2 0 0 2 2 2 1 Mitochondrial ribosomal subunit S27 PP2C_2 PF13672.6 CRK26673.1 - 0.017 14.7 0.4 0.045 13.4 0.0 1.8 2 0 0 2 2 2 0 Protein phosphatase 2C SpoIIE PF07228.12 CRK26673.1 - 0.022 14.7 0.1 1 9.3 0.0 2.4 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) Thioredoxin_15 PF18403.1 CRK26673.1 - 0.041 13.8 0.0 0.12 12.3 0.0 1.7 1 1 0 1 1 1 0 Thioredoxin-like domain BRE1 PF08647.11 CRK26673.1 - 4.1 7.5 5.1 0.46 10.6 0.5 1.8 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase ATG16 PF08614.11 CRK26673.1 - 5.7 7.1 6.5 6.2 7.0 5.1 1.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Ribonuclease_3 PF00636.26 CRK26674.1 - 9.2e-13 48.7 0.0 2.3e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 CRK26674.1 - 1.5e-08 34.8 0.0 2.6e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.26 CRK26674.1 - 0.0044 17.7 0.0 0.01 16.5 0.0 1.7 1 0 0 1 1 1 1 Double-stranded RNA binding motif ACBP PF00887.19 CRK26675.1 - 2.2e-11 43.8 0.0 5.9e-11 42.4 0.0 1.8 1 0 0 1 1 1 1 Acyl CoA binding protein Ribonuclease_T2 PF00445.18 CRK26676.1 - 4.8e-40 137.7 6.0 7.5e-40 137.1 6.0 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family Molybdopterin PF00384.22 CRK26677.1 - 1.1e-73 248.6 0.0 9.1e-72 242.3 0.0 2.1 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.6 CRK26677.1 - 8.8e-21 73.8 0.2 3.2e-20 72.0 0.2 2.0 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH_dhqG_C PF09326.11 CRK26677.1 - 8.2e-18 64.8 0.0 2.1e-17 63.5 0.0 1.8 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal NADH-G_4Fe-4S_3 PF10588.9 CRK26677.1 - 5.2e-17 61.1 0.2 5.2e-17 61.1 0.2 2.1 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2 PF00111.27 CRK26677.1 - 5e-09 36.0 0.5 5e-09 36.0 0.5 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Lyx_isomer PF07385.12 CRK26677.1 - 0.056 12.7 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 D-lyxose isomerase TPP_enzyme_M PF00205.22 CRK26677.1 - 0.063 13.0 0.0 0.2 11.4 0.0 1.8 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Fer4 PF00037.27 CRK26677.1 - 0.12 12.3 1.1 3.5 7.6 0.3 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_19 PF06902.11 CRK26677.1 - 0.38 10.9 1.8 4.4 7.5 1.8 2.5 1 1 0 1 1 1 0 Divergent 4Fe-4S mono-cluster Fer4_4 PF12800.7 CRK26677.1 - 9.2 7.0 6.5 1.5 9.5 1.6 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain UPF0061 PF02696.14 CRK26678.1 - 1e-122 410.3 0.0 1.3e-122 409.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family Aldo_ket_red PF00248.21 CRK26679.1 - 1e-39 136.5 0.0 3.8e-38 131.4 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family XRCC4 PF06632.12 CRK26680.1 - 2.2e-07 30.1 14.6 5.9e-07 28.7 14.6 1.6 1 1 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 Snapin_Pallidin PF14712.6 CRK26680.1 - 0.0094 16.4 2.4 0.036 14.5 2.0 2.1 2 0 0 2 2 2 1 Snapin/Pallidin BUD22 PF09073.10 CRK26680.1 - 0.035 13.5 19.5 0.046 13.1 19.5 1.2 1 0 0 1 1 1 0 BUD22 NOA36 PF06524.12 CRK26680.1 - 0.28 10.5 13.3 0.42 9.9 13.3 1.2 1 0 0 1 1 1 0 NOA36 protein ORC6 PF05460.13 CRK26680.1 - 0.42 9.8 11.7 0.6 9.3 11.7 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Raftlin PF15250.6 CRK26680.1 - 0.43 9.3 7.6 0.54 9.0 7.6 1.2 1 0 0 1 1 1 0 Raftlin SURF2 PF05477.11 CRK26680.1 - 0.9 9.2 11.9 1.4 8.6 11.9 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) PPP4R2 PF09184.11 CRK26680.1 - 1 8.9 14.8 1.4 8.5 14.8 1.2 1 0 0 1 1 1 0 PPP4R2 DUF966 PF06136.13 CRK26680.1 - 2.6 7.7 11.6 3.5 7.2 11.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) SAPS PF04499.15 CRK26680.1 - 2.8 6.6 9.0 3.6 6.3 9.0 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4407 PF14362.6 CRK26680.1 - 9.8 5.4 16.3 16 4.8 16.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Kelch_6 PF13964.6 CRK26682.1 - 0.039 14.3 0.0 3.2 8.2 0.0 2.7 2 0 0 2 2 2 0 Kelch motif OCRE PF17780.1 CRK26682.1 - 0.11 12.5 0.0 15 5.7 0.0 2.2 2 0 0 2 2 2 0 OCRE domain Methyltr_RsmB-F PF01189.17 CRK26683.1 - 1.1e-75 253.7 0.0 2.2e-75 252.7 0.0 1.5 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Cpn60_TCP1 PF00118.24 CRK26683.1 - 8.4e-66 222.6 5.5 4.2e-41 141.1 2.7 2.2 1 1 1 2 2 2 2 TCP-1/cpn60 chaperonin family Cofilin_ADF PF00241.20 CRK26683.1 - 5.7e-38 129.4 0.3 1.1e-37 128.5 0.3 1.5 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Methyltr_RsmF_N PF17125.5 CRK26683.1 - 1.1e-06 29.0 0.0 3.2e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF Met_10 PF02475.16 CRK26683.1 - 0.0017 18.1 0.0 0.0037 17.0 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein Toprim_Crpt PF13342.6 CRK26683.1 - 0.044 13.8 0.1 0.12 12.3 0.1 1.7 1 0 0 1 1 1 0 C-terminal repeat of topoisomerase DUF2431 PF10354.9 CRK26683.1 - 0.15 12.3 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) Blt1 PF12754.7 CRK26684.1 - 9.8e-37 126.6 0.5 1.4e-36 126.1 0.5 1.2 1 0 0 1 1 1 1 Blt1 N-terminal domain Blt1_C PF17183.4 CRK26684.1 - 5e-15 54.8 1.4 9.2e-15 54.0 1.4 1.4 1 0 0 1 1 1 1 Get5 carboxyl domain ubiquitin PF00240.23 CRK26684.1 - 4.8e-05 23.0 0.0 7.7e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Histone_HNS PF00816.21 CRK26685.1 - 0.18 12.7 1.2 0.32 11.9 1.2 1.3 1 0 0 1 1 1 0 H-NS histone family Antimicrobial24 PF16049.5 CRK26685.1 - 0.34 10.9 2.8 0.77 9.8 2.8 1.5 1 0 0 1 1 1 0 Frog antimicrobial peptide FAD_binding_4 PF01565.23 CRK26686.1 - 3.4e-20 72.2 0.1 6.9e-20 71.2 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 CRK26686.1 - 0.023 14.8 0.0 0.063 13.4 0.0 1.7 1 0 0 1 1 1 0 Berberine and berberine like AflR PF08493.10 CRK26687.1 - 0.091 12.2 3.3 0.11 11.9 3.3 1.1 1 0 0 1 1 1 0 Aflatoxin regulatory protein Phage_endo_I PF05367.11 CRK26688.1 - 0.093 12.3 0.2 0.29 10.7 0.1 1.7 1 1 1 2 2 2 0 Phage endonuclease I DUF4660 PF15559.6 CRK26688.1 - 0.098 13.0 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4660) Zn_clus PF00172.18 CRK26689.1 - 9.9e-05 22.4 13.3 0.0012 18.9 13.3 2.2 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 CRK26689.1 - 0.0069 15.2 0.2 0.0097 14.7 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain CTNNB1_binding PF08347.11 CRK26690.1 - 0.01 16.0 3.4 0.015 15.5 3.4 1.3 1 0 0 1 1 1 0 N-terminal CTNNB1 binding ZT_dimer PF16916.5 CRK26692.1 - 5.3e-06 26.5 0.1 7.8e-06 25.9 0.1 1.2 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Serinc PF03348.15 CRK26693.1 - 1.1e-11 44.4 0.4 1.2e-11 44.2 0.4 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) Wyosine_form PF08608.12 CRK26709.1 - 1.9e-28 98.6 0.0 7e-28 96.8 0.0 1.8 2 0 0 2 2 2 1 Wyosine base formation PPR_2 PF13041.6 CRK26713.1 - 2.2e-27 95.0 2.0 1.3e-12 47.7 0.1 6.1 4 1 1 5 5 5 5 PPR repeat family PPR_3 PF13812.6 CRK26713.1 - 1.5e-15 57.0 0.0 5.4e-07 29.6 0.0 5.1 5 1 0 5 5 5 2 Pentatricopeptide repeat domain PPR PF01535.20 CRK26713.1 - 8.6e-11 41.3 3.4 0.011 16.0 0.3 6.4 6 0 0 6 6 6 2 PPR repeat GST_N PF02798.20 CRK26713.1 - 3e-10 40.3 0.0 7.7e-10 39.0 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain PPR_long PF17177.4 CRK26713.1 - 9.6e-08 31.6 0.0 0.00077 18.9 0.0 3.6 2 1 2 4 4 4 3 Pentacotripeptide-repeat region of PRORP GST_N_3 PF13417.6 CRK26713.1 - 4.8e-07 30.1 0.0 1.2e-06 28.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain PPR_1 PF12854.7 CRK26713.1 - 1.5e-06 27.8 0.6 0.2 11.4 0.0 5.4 6 0 0 6 6 6 1 PPR repeat GST_C_2 PF13410.6 CRK26713.1 - 3.3e-06 27.0 0.2 1.5e-05 25.0 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CRK26713.1 - 1.4e-05 25.2 0.0 5.4e-05 23.3 0.0 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 CRK26713.1 - 0.0002 21.6 0.0 0.00067 19.9 0.0 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CRK26713.1 - 0.0027 17.9 0.0 0.0096 16.1 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain RPM2 PF08579.11 CRK26713.1 - 0.096 13.1 0.0 0.29 11.5 0.0 1.8 1 0 0 1 1 1 0 Mitochondrial ribonuclease P subunit (RPM2) DUF2839 PF10999.8 CRK26715.1 - 0.066 13.6 0.2 0.085 13.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2839) SAP18 PF06487.12 CRK26717.1 - 6.7e-32 110.6 0.0 7.9e-32 110.3 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Prp18 PF02840.15 CRK26719.1 - 2.4e-51 173.5 1.6 2.7e-51 173.4 0.0 1.8 2 1 0 2 2 2 1 Prp18 domain PRP4 PF08799.11 CRK26719.1 - 6.3e-10 38.4 3.8 6.3e-10 38.4 3.8 2.9 3 0 0 3 3 3 2 pre-mRNA processing factor 4 (PRP4) like ESP PF16590.5 CRK26719.1 - 0.14 12.5 0.1 0.27 11.5 0.1 1.4 1 0 0 1 1 1 0 Exocrine gland-secreting peptide Borrelia_P83 PF05262.11 CRK26719.1 - 2.2 6.7 10.8 2.7 6.4 10.8 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein CDC45 PF02724.14 CRK26719.1 - 2.3 6.4 9.8 3 6.0 9.8 1.1 1 0 0 1 1 1 0 CDC45-like protein RPN7 PF10602.9 CRK26721.1 - 2e-10 40.7 0.6 2.8e-10 40.2 0.6 1.2 1 0 0 1 1 1 1 26S proteasome subunit RPN7 DUF3813 PF12758.7 CRK26721.1 - 0.22 11.9 0.9 0.47 10.8 0.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3813) RPN7 PF10602.9 CRK26724.1 - 1.8e-45 154.8 0.3 2.8e-45 154.1 0.3 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 CRK26724.1 - 3.9e-11 43.4 0.0 2e-10 41.1 0.0 2.2 2 0 0 2 2 2 1 PCI domain Fungal_trans PF04082.18 CRK26727.1 - 8.8e-26 90.5 0.0 8.8e-26 90.5 0.0 1.8 2 0 0 2 2 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK26727.1 - 1.1e-10 41.5 13.6 1.9e-10 40.7 13.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIA PF03153.13 CRK26727.1 - 0.0016 18.5 21.5 0.0016 18.5 21.5 1.6 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Fer2 PF00111.27 CRK26727.1 - 0.0062 16.5 1.7 1.4 8.9 0.0 2.5 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DUF2722 PF10846.8 CRK26727.1 - 0.023 13.7 20.0 0.04 12.9 20.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 CRK26727.1 - 0.094 12.3 28.4 0.17 11.4 28.4 1.3 1 0 0 1 1 1 0 Spt20 family DUF2924 PF11149.8 CRK26727.1 - 0.18 12.2 4.8 0.46 10.9 4.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2924) EIIBC-GUT_N PF03612.14 CRK26727.1 - 0.19 11.5 1.1 0.34 10.6 1.1 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus TERB2 PF15101.6 CRK26727.1 - 0.33 11.0 8.8 0.75 9.8 8.8 1.6 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF4407 PF14362.6 CRK26727.1 - 0.8 9.0 5.6 1.9 7.8 4.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) eIF-3_zeta PF05091.12 CRK26727.1 - 1.2 8.1 9.9 2.2 7.2 9.9 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RR_TM4-6 PF06459.12 CRK26727.1 - 1.3 8.8 6.6 2.5 7.8 4.1 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Suf PF05843.14 CRK26727.1 - 2 8.3 11.4 0.12 12.3 6.1 1.6 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) BRF1 PF07741.13 CRK26727.1 - 2.8 8.4 8.2 6.9 7.1 8.2 1.6 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Neur_chan_memb PF02932.16 CRK26727.1 - 5 7.1 7.6 0.38 10.8 2.5 1.7 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region FAM176 PF14851.6 CRK26727.1 - 5 6.8 6.3 11 5.7 6.3 1.5 1 0 0 1 1 1 0 FAM176 family PAT1 PF09770.9 CRK26727.1 - 6 5.0 20.1 9.8 4.3 20.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AMP_N PF05195.16 CRK26728.1 - 2.4e-09 37.0 0.0 3.4e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Peptidase_M24 PF00557.24 CRK26729.1 - 1.6e-37 129.2 0.0 2.2e-37 128.8 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 HRXXH PF13933.6 CRK26729.1 - 0.23 11.0 0.0 13 5.2 0.0 2.1 2 0 0 2 2 2 0 Putative peptidase family Lectin_leg-like PF03388.13 CRK26730.1 - 2.4e-22 79.4 0.0 3.7e-22 78.8 0.0 1.2 1 0 0 1 1 1 1 Legume-like lectin family UPF0242 PF06785.11 CRK26730.1 - 0.0058 16.8 1.1 0.0092 16.1 1.1 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus AAA_13 PF13166.6 CRK26730.1 - 0.054 12.2 0.2 0.054 12.2 0.2 1.7 2 0 0 2 2 2 0 AAA domain Fib_alpha PF08702.10 CRK26730.1 - 0.093 12.9 0.3 0.093 12.9 0.3 1.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF1515 PF07439.11 CRK26730.1 - 0.15 12.1 0.5 0.32 11.0 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) Spt20 PF12090.8 CRK26730.1 - 0.31 10.6 5.0 0.43 10.2 5.0 1.2 1 0 0 1 1 1 0 Spt20 family Alg6_Alg8 PF03155.15 CRK26731.1 - 4.2e-177 589.9 28.4 5e-177 589.7 28.4 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family WAC_Acf1_DNA_bd PF10537.9 CRK26732.1 - 5.5e-39 132.8 0.0 1.8e-38 131.1 0.0 2.0 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 CRK26732.1 - 3.9e-34 117.1 0.7 1.7e-17 63.7 0.1 4.5 5 0 0 5 5 5 2 Williams-Beuren syndrome DDT (WSD), D-TOX E motif WHIM1 PF15612.6 CRK26732.1 - 3.2e-17 61.6 1.2 3.4e-07 29.6 0.0 3.2 4 0 0 4 4 4 2 WSTF, HB1, Itc1p, MBD9 motif 1 DDT PF02791.17 CRK26732.1 - 5.1e-16 58.7 1.3 1e-15 57.8 1.3 1.5 1 0 0 1 1 1 1 DDT domain NCBP3 PF10309.9 CRK26732.1 - 0.0045 16.8 0.0 4.9 7.1 0.0 2.6 2 0 0 2 2 2 2 Nuclear cap-binding protein subunit 3 Parvo_NS1 PF01057.17 CRK26732.1 - 0.013 14.6 0.0 5 6.1 0.0 2.5 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 TusA PF01206.17 CRK26732.1 - 0.073 12.9 0.0 21 5.0 0.0 2.7 2 0 0 2 2 2 0 Sulfurtransferase TusA DUF2510 PF10708.9 CRK26732.1 - 0.097 12.4 6.1 7.4 6.4 0.6 3.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2510) DUF5093 PF17011.5 CRK26732.1 - 0.16 12.2 2.6 30 4.9 0.2 3.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5093) DUF1465 PF07323.12 CRK26732.1 - 1.1 9.1 8.8 9.7 6.0 1.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1465) HMG-CoA_red PF00368.18 CRK26736.1 - 1.8e-26 93.1 0.1 1.9e-26 92.9 0.1 1.0 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Pkinase PF00069.25 CRK26737.1 - 2.7e-40 138.4 0.1 3.3e-22 79.1 0.1 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CRK26737.1 - 3.8e-14 52.6 0.3 1.3e-09 37.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 CRK26737.1 - 0.031 13.1 0.1 0.072 11.9 0.1 1.4 1 1 0 1 1 1 0 Fungal protein kinase Med26 PF08711.11 CRK26738.1 - 9.5e-08 32.0 0.0 2.1e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Umbravirus_LDM PF04817.12 CRK26738.1 - 0.041 13.2 5.9 0.073 12.4 5.9 1.4 1 0 0 1 1 1 0 Umbravirus long distance movement (LDM) family Brr6_like_C_C PF10104.9 CRK26739.1 - 3.1e-30 104.7 0.1 5.9e-30 103.8 0.1 1.4 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain DUF4681 PF15732.5 CRK26740.1 - 0.024 14.9 1.9 0.061 13.6 1.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4681) OrsD PF12013.8 CRK26740.1 - 0.024 15.1 2.7 0.61 10.6 0.0 3.2 3 0 0 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_4 PF13894.6 CRK26742.1 - 0.0017 19.1 17.2 0.048 14.5 1.8 4.2 3 0 0 3 3 3 2 C2H2-type zinc finger TFIIA PF03153.13 CRK26742.1 - 0.0059 16.7 27.8 0.0059 16.7 27.8 1.7 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit DUF1917 PF08939.10 CRK26742.1 - 0.66 9.8 8.1 1.3 8.9 8.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1917) CAC1F_C PF16885.5 CRK26742.1 - 1.8 8.2 14.7 0.37 10.4 11.2 1.6 2 0 0 2 2 2 0 Voltage-gated calcium channel subunit alpha, C-term Lin-8 PF03353.15 CRK26742.1 - 2.8 7.4 21.2 4.9 6.6 21.2 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist zf-C2H2 PF00096.26 CRK26742.1 - 2.9 8.5 15.7 0.34 11.4 1.1 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type PIEZO PF15917.5 CRK26742.1 - 9.8 5.6 19.1 17 4.8 19.1 1.2 1 0 0 1 1 1 0 Piezo YdjC PF04794.12 CRK26743.1 - 0.081 12.9 0.2 0.081 12.9 0.2 1.1 1 0 0 1 1 1 0 YdjC-like protein WD40 PF00400.32 CRK26744.1 - 6.6e-27 93.2 21.0 8.3e-08 32.8 0.2 11.2 10 1 1 11 11 11 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK26744.1 - 1.2e-05 25.5 0.1 4.1 7.8 0.0 5.9 5 2 3 8 8 8 1 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 CRK26744.1 - 0.023 14.6 1.9 0.14 12.1 0.2 3.0 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 CRK26744.1 - 0.089 11.7 0.0 3.9 6.4 0.0 2.8 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40 PF00400.32 CRK26745.1 - 2e-17 63.2 0.4 1.7e-06 28.7 0.3 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat WD40 PF00400.32 CRK26746.1 - 4.4e-12 46.3 3.9 0.78 10.7 0.0 6.7 5 1 1 6 6 6 5 WD domain, G-beta repeat PD40 PF07676.12 CRK26746.1 - 0.024 14.6 0.2 0.1 12.6 0.2 2.1 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat CDC45 PF02724.14 CRK26746.1 - 3.7 5.7 19.3 5 5.3 19.3 1.1 1 0 0 1 1 1 0 CDC45-like protein WD40 PF00400.32 CRK26747.1 - 2.4e-18 66.1 8.3 2.4e-08 34.5 0.2 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK26747.1 - 0.00029 21.1 0.0 0.99 9.7 0.0 3.6 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CRK26747.1 - 0.031 13.2 0.0 1.2 8.1 0.0 2.3 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PUL PF08324.11 CRK26748.1 - 9.2e-73 244.9 0.0 1.8e-72 243.9 0.0 1.5 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 CRK26748.1 - 7.9e-45 151.8 0.1 1.4e-44 151.0 0.1 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 CRK26748.1 - 8.9e-31 105.5 8.4 3.1e-06 27.8 0.0 8.2 8 0 0 8 8 8 5 WD domain, G-beta repeat DNA_pol_A_exoN PF18305.1 CRK26748.1 - 0.012 15.9 0.1 6.2 7.2 0.0 3.1 3 0 0 3 3 3 0 3' to 5' exonuclease C-terminal domain WD40_like PF17005.5 CRK26748.1 - 0.016 14.6 0.0 0.029 13.7 0.0 1.5 1 0 0 1 1 1 0 WD40-like domain ANAPC4_WD40 PF12894.7 CRK26748.1 - 0.039 14.2 0.3 7.1 7.0 0.0 3.7 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 CRK26748.1 - 0.087 13.3 0.4 0.52 10.9 0.1 2.6 2 0 0 2 2 2 0 PQQ-like domain DUF1593 PF07632.11 CRK26750.1 - 1.9e-70 237.2 0.1 2.3e-38 132.1 0.1 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF1593) CSTF1_dimer PF16699.5 CRK26750.1 - 0.21 11.4 0.0 0.45 10.3 0.0 1.5 1 0 0 1 1 1 0 Cleavage stimulation factor subunit 1, dimerisation domain SRR1 PF07985.12 CRK26751.1 - 9.3e-15 54.4 0.0 1.7e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 SRR1 Vps53_N PF04100.12 CRK26753.1 - 7.7e-63 212.7 1.7 8.7e-63 212.6 1.7 1.0 1 0 0 1 1 1 1 Vps53-like, N-terminal Vps54_N PF10475.9 CRK26753.1 - 4.3e-08 32.8 2.9 5.1e-08 32.6 2.9 1.1 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Zw10 PF06248.13 CRK26753.1 - 1.2e-05 24.2 3.7 1.5e-05 23.8 3.7 1.1 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 DUF5082 PF16888.5 CRK26753.1 - 0.016 15.5 3.8 0.072 13.4 1.4 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) Spc7 PF08317.11 CRK26753.1 - 0.042 12.7 5.7 0.023 13.6 3.2 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF3919 PF13057.6 CRK26753.1 - 0.076 12.6 0.0 0.098 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3919) DUF3450 PF11932.8 CRK26753.1 - 0.12 11.7 7.2 0.12 11.6 6.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) Flagellin_N PF00669.20 CRK26753.1 - 0.12 12.4 4.9 0.44 10.7 0.3 2.3 1 1 1 2 2 2 0 Bacterial flagellin N-terminal helical region COG2 PF06148.11 CRK26753.1 - 0.15 12.1 6.4 3.9 7.6 4.2 3.1 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 XhlA PF10779.9 CRK26753.1 - 0.24 11.7 1.5 0.51 10.6 0.5 2.0 2 0 0 2 2 2 0 Haemolysin XhlA DUF1664 PF07889.12 CRK26753.1 - 0.3 11.1 3.1 0.37 10.8 1.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 CRK26753.1 - 2.6 8.1 5.9 4.6 7.3 4.8 2.0 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Glyco_hydro_18 PF00704.28 CRK26754.1 - 6.9e-68 229.7 0.0 7.9e-68 229.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Methyltransf_23 PF13489.6 CRK26756.1 - 4.6e-05 23.3 0.0 7.1e-05 22.7 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CRK26756.1 - 9e-05 23.1 0.0 0.00016 22.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK26756.1 - 0.00055 19.8 0.0 0.00058 19.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK26756.1 - 0.0091 16.7 0.0 0.013 16.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK26756.1 - 0.051 14.3 0.0 0.091 13.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 CRK26756.1 - 0.068 12.5 0.0 0.077 12.3 0.0 1.1 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_9 PF08003.11 CRK26756.1 - 0.17 10.8 0.0 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Med1 PF10744.9 CRK26759.1 - 1.4e-118 396.6 0.0 1.8e-118 396.2 0.0 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 Pkinase PF00069.25 CRK26760.1 - 7.3e-41 140.3 0.0 7.7e-39 133.6 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CRK26760.1 - 7.3e-22 77.9 0.0 2e-21 76.5 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Exostosin PF03016.15 CRK26760.1 - 0.033 13.4 0.0 0.069 12.4 0.0 1.5 1 0 0 1 1 1 0 Exostosin family GCP_C_terminal PF04130.13 CRK26761.1 - 1.1e-98 330.6 0.0 1.6e-98 330.0 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 CRK26761.1 - 9.9e-85 284.8 0.0 2.6e-84 283.4 0.0 1.7 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal AMP-binding PF00501.28 CRK26762.1 - 3.3e-88 296.1 0.1 5.2e-88 295.5 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme BCAS2 PF05700.11 CRK26762.1 - 2.6e-52 177.5 1.3 3.8e-52 177.0 1.3 1.2 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) AMP-binding_C PF13193.6 CRK26762.1 - 2.1e-10 41.4 0.1 5.5e-10 40.1 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain cNMP_binding PF00027.29 CRK26763.1 - 2.7e-40 136.3 0.0 9.2e-22 76.9 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 CRK26763.1 - 1.6e-08 34.0 0.3 2.9e-08 33.3 0.3 1.4 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit zf-PHD-like PF15446.6 CRK26764.1 - 3.6e-70 234.9 13.6 6.6e-70 234.1 13.6 1.5 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain Chromo PF00385.24 CRK26764.1 - 6.2e-07 29.2 0.1 4.3e-05 23.3 0.1 2.9 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain SNF2_N PF00176.23 CRK26764.1 - 5.5e-05 22.1 0.3 0.00043 19.1 0.3 1.9 1 1 0 1 1 1 1 SNF2 family N-terminal domain PHD PF00628.29 CRK26764.1 - 0.00016 21.5 19.5 0.00016 21.5 7.2 3.4 2 1 1 3 3 3 2 PHD-finger Zf_RING PF16744.5 CRK26764.1 - 0.0013 18.8 10.0 0.14 12.3 3.2 2.7 2 0 0 2 2 2 2 KIAA1045 RING finger C1_1 PF00130.22 CRK26764.1 - 0.0059 16.5 3.1 0.0059 16.5 3.1 4.5 4 1 1 5 5 5 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.6 CRK26764.1 - 0.49 10.0 8.2 0.083 12.5 0.3 3.2 3 0 0 3 3 3 0 PHD-finger DUF2318 PF10080.9 CRK26764.1 - 0.94 9.6 6.8 0.087 12.9 0.7 2.3 3 0 0 3 3 3 0 Predicted membrane protein (DUF2318) RPA_interact_C PF14768.6 CRK26764.1 - 1 10.0 6.1 3.6 8.2 6.1 2.0 1 0 0 1 1 1 0 Replication protein A interacting C-terminal DUF866 PF05907.13 CRK26764.1 - 3.4 7.6 5.9 30 4.5 2.3 2.6 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF866) SpoU_methylase PF00588.19 CRK26765.1 - 6.9e-27 94.4 0.0 1.1e-26 93.7 0.0 1.3 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 CRK26765.1 - 1.5e-10 41.2 0.0 4.2e-10 39.8 0.0 1.8 2 0 0 2 2 2 1 RNA 2'-O ribose methyltransferase substrate binding RepB-RCR_reg PF10723.9 CRK26766.1 - 0.073 13.0 0.3 0.12 12.4 0.3 1.3 1 0 0 1 1 1 0 Replication regulatory protein RepB MBF1 PF08523.10 CRK26769.1 - 9.8e-22 77.2 0.4 1.7e-21 76.4 0.4 1.4 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 CRK26769.1 - 1.4e-09 37.9 0.1 2.3e-09 37.2 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix MRP-L27 PF09809.9 CRK26769.1 - 0.021 14.7 0.1 0.026 14.3 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L27 HTH_31 PF13560.6 CRK26769.1 - 0.049 14.0 0.0 0.083 13.3 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain DUF1365 PF07103.11 CRK26771.1 - 5.7e-62 209.5 0.0 7.7e-62 209.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) Form-deh_trans PF09163.11 CRK26771.1 - 0.032 14.0 0.3 0.08 12.7 0.3 1.6 1 0 0 1 1 1 0 Formate dehydrogenase N, transmembrane GST_N_3 PF13417.6 CRK26773.1 - 2.8e-09 37.3 0.2 5.2e-09 36.4 0.2 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CRK26773.1 - 4.3e-08 33.1 1.6 1.1e-07 31.8 1.6 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CRK26773.1 - 7.2e-05 22.9 0.0 0.00014 22.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 CRK26773.1 - 0.0007 19.8 0.1 0.0016 18.7 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 CRK26773.1 - 0.085 13.1 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Aft1_HRR PF11787.8 CRK26774.1 - 1.6e-27 96.5 3.6 1.6e-27 96.5 3.6 4.3 3 1 1 4 4 4 1 Aft1 HRR domain Aft1_HRA PF11786.8 CRK26774.1 - 3.7e-23 81.6 10.2 3.7e-23 81.6 10.2 3.6 3 2 1 4 4 4 1 Aft1 HRA domain Aft1_OSA PF11785.8 CRK26774.1 - 3.7e-19 68.9 8.0 3.7e-19 68.9 8.0 3.4 3 0 0 3 3 3 1 Aft1 osmotic stress response (OSM) domain bZIP_1 PF00170.21 CRK26774.1 - 4.2e-13 49.2 5.5 7e-13 48.5 5.5 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CRK26774.1 - 6.5e-06 26.1 5.5 1.3e-05 25.2 5.5 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 CRK26774.1 - 0.0012 19.4 3.2 0.0024 18.3 3.2 1.6 1 0 0 1 1 1 1 bZIP Maf transcription factor MbeD_MobD PF04899.12 CRK26774.1 - 0.093 12.9 0.9 0.17 12.0 0.9 1.4 1 0 0 1 1 1 0 MbeD/MobD like FAM76 PF16046.5 CRK26774.1 - 0.16 11.3 6.3 0.29 10.4 6.3 1.4 1 0 0 1 1 1 0 FAM76 protein MIS13 PF08202.11 CRK26775.1 - 1.6e-61 208.3 2.0 3.6e-61 207.1 2.0 1.6 1 0 0 1 1 1 1 Mis12-Mtw1 protein family DUF5082 PF16888.5 CRK26775.1 - 0.22 11.8 2.5 2 8.7 1.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) YvrJ PF12841.7 CRK26775.1 - 0.43 10.2 1.8 12 5.5 0.0 2.3 2 0 0 2 2 2 0 YvrJ protein family ZapB PF06005.12 CRK26775.1 - 0.58 10.6 9.5 7.8 7.0 3.5 2.7 2 0 0 2 2 2 0 Cell division protein ZapB Alanine_zipper PF11839.8 CRK26775.1 - 0.63 10.5 5.6 18 5.8 0.0 3.5 3 0 0 3 3 3 0 Alanine-zipper, major outer membrane lipoprotein DUF2205 PF10224.9 CRK26775.1 - 2.8 8.0 5.2 4.3 7.4 0.3 2.5 2 0 0 2 2 2 0 Short coiled-coil protein EMP24_GP25L PF01105.24 CRK26776.1 - 5.3e-42 143.8 0.0 6.5e-42 143.5 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF4686 PF15742.5 CRK26776.1 - 0.12 11.5 0.3 0.15 11.2 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4686) Helicase_RecD PF05127.14 CRK26776.1 - 0.12 12.2 0.0 0.28 11.0 0.0 1.7 2 0 0 2 2 2 0 Helicase zf-U1 PF06220.12 CRK26777.1 - 5.3e-22 77.3 3.4 7.9e-22 76.7 3.4 1.3 1 0 0 1 1 1 1 U1 zinc finger HD PF01966.22 CRK26782.1 - 1e-05 25.7 1.1 3.3e-05 24.1 0.4 2.1 2 1 0 2 2 2 1 HD domain AMPK1_CBM PF16561.5 CRK26783.1 - 0.00079 19.6 0.0 0.0016 18.6 0.0 1.5 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Zip PF02535.22 CRK26783.1 - 0.39 9.9 3.2 0.39 9.9 3.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 CRK26783.1 - 0.46 9.2 4.6 0.59 8.8 4.6 1.1 1 0 0 1 1 1 0 Presenilin GEMIN8 PF15348.6 CRK26783.1 - 0.68 10.2 8.0 1.5 9.1 8.0 1.5 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Tmemb_cc2 PF10267.9 CRK26783.1 - 0.76 8.9 6.0 1.2 8.2 6.0 1.4 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein NPR3 PF03666.13 CRK26783.1 - 0.91 8.2 8.4 1.2 7.8 8.4 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Sec3_C PF09763.9 CRK26783.1 - 1.7 7.0 5.5 1.9 6.7 5.5 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 Pkinase_fungal PF17667.1 CRK26783.1 - 1.9 7.1 6.7 2.8 6.6 6.7 1.1 1 0 0 1 1 1 0 Fungal protein kinase Hid1 PF12722.7 CRK26783.1 - 8.1 4.4 6.5 10 4.1 6.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Pectate_lyase PF03211.13 CRK26784.1 - 1.3e-79 266.4 0.2 2.1e-79 265.8 0.2 1.3 1 0 0 1 1 1 1 Pectate lyase Amidohydro_2 PF04909.14 CRK26784.1 - 4.7e-16 59.4 2.4 6.5e-15 55.7 1.4 2.8 2 1 0 2 2 2 1 Amidohydrolase Spt5-NGN PF03439.13 CRK26784.1 - 0.0039 17.1 0.0 4.5 7.2 0.0 2.4 2 0 0 2 2 2 2 Early transcription elongation factor of RNA pol II, NGN section NPR3 PF03666.13 CRK26784.1 - 5.6 5.7 7.3 8.6 5.0 7.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Macoilin PF09726.9 CRK26784.1 - 8.3 4.8 14.9 12 4.3 14.9 1.2 1 0 0 1 1 1 0 Macoilin family AIM24 PF01987.17 CRK26785.1 - 9.8e-52 175.7 0.2 1.2e-51 175.4 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 TFIIA PF03153.13 CRK26785.1 - 8.4 6.3 28.5 11 5.8 28.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CysA_C_terminal PF17850.1 CRK26789.1 - 0.15 12.6 1.6 0.51 10.9 0.0 2.5 2 1 0 2 2 2 0 CysA C-terminal regulatory domain TRP PF06011.12 CRK26790.1 - 5.2e-159 529.5 35.6 6.5e-159 529.2 35.6 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 CRK26790.1 - 6.4e-42 143.2 0.4 1.3e-41 142.3 0.4 1.5 1 0 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.15 CRK26790.1 - 0.014 15.8 0.1 0.025 15.0 0.1 1.4 1 0 0 1 1 1 0 ML domain PhzC-PhzF PF02567.16 CRK26791.1 - 6.4e-35 121.0 0.1 2.4e-34 119.1 0.1 1.8 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein Ribonuc_L-PSP PF01042.21 CRK26792.1 - 3.6e-35 120.6 0.1 4.3e-35 120.3 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Phlebovirus_G2 PF07245.11 CRK26792.1 - 0.00066 18.3 0.0 0.00067 18.3 0.0 1.1 1 0 0 1 1 1 1 Phlebovirus glycoprotein G2 DUF3433 PF11915.8 CRK26793.1 - 8.1e-50 167.2 18.6 8.2e-19 67.9 2.5 4.9 6 0 0 6 6 6 3 Protein of unknown function (DUF3433) Insulin_TMD PF17870.1 CRK26793.1 - 0.025 14.6 4.9 3.4 7.8 0.4 2.8 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment PglL_A PF15864.5 CRK26793.1 - 0.31 10.8 1.5 40 4.1 0.1 3.4 2 0 0 2 2 2 0 Protein glycosylation ligase DotU PF09850.9 CRK26794.1 - 0.13 12.0 6.9 0.2 11.4 3.2 2.3 2 0 0 2 2 2 0 Type VI secretion system protein DotU GvpG PF05120.12 CRK26794.1 - 1.4 8.9 14.6 0.056 13.4 7.6 2.2 2 0 0 2 2 2 0 Gas vesicle protein G Borrelia_P83 PF05262.11 CRK26794.1 - 1.7 7.1 14.6 2.4 6.5 14.6 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein CSN5_C PF18323.1 CRK26794.1 - 7 7.6 9.4 62 4.6 9.4 2.7 1 1 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain FapA PF03961.13 CRK26794.1 - 9.1 4.8 9.9 18 3.8 9.9 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A Vac7 PF12751.7 CRK26795.1 - 4e-146 487.3 9.7 8.7e-129 430.3 0.1 3.2 3 1 0 3 3 3 2 Vacuolar segregation subunit 7 RrnaAD PF00398.20 CRK26797.1 - 1.8e-58 197.7 0.0 2.6e-58 197.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 CRK26797.1 - 4.9e-06 27.2 0.0 1.1e-05 26.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 CRK26797.1 - 0.00026 20.8 0.0 0.00042 20.1 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 CRK26797.1 - 0.00067 19.0 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 CRK26797.1 - 0.0017 18.9 0.0 0.0041 17.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK26797.1 - 0.0035 18.1 0.1 0.016 16.0 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.6 CRK26797.1 - 0.0043 16.9 0.0 0.0093 15.8 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_28 PF02636.17 CRK26797.1 - 0.033 13.8 0.0 0.17 11.5 0.0 2.0 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_31 PF13847.6 CRK26797.1 - 0.042 13.6 0.0 0.072 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 CRK26797.1 - 0.046 13.2 0.0 0.09 12.2 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.14 CRK26797.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.18 CRK26797.1 - 0.15 11.3 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PRP1_N PF06424.12 CRK26798.1 - 3.7e-51 173.4 6.8 4.7e-51 173.1 6.8 1.1 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal AAA_lid_2 PF17863.1 CRK26798.1 - 0.028 14.2 1.4 0.053 13.4 0.5 1.8 2 0 0 2 2 2 0 AAA lid domain NuDC PF16273.5 CRK26798.1 - 6.6 7.3 14.9 0.17 12.4 4.7 2.3 2 0 0 2 2 2 0 Nuclear distribution C domain RrnaAD PF00398.20 CRK26799.1 - 3.5e-54 183.6 0.0 7.2e-54 182.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 CRK26799.1 - 0.0018 18.9 0.0 0.0041 17.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CRK26799.1 - 0.0036 17.2 0.0 0.0065 16.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK26799.1 - 0.014 16.1 0.0 0.052 14.3 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain PCMT PF01135.19 CRK26799.1 - 0.055 13.2 0.0 0.086 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 CRK26799.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DUF3474 PF11960.8 CRK26799.1 - 0.11 12.7 0.1 0.24 11.6 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) PRP1_N PF06424.12 CRK26801.1 - 2.7e-50 170.6 7.3 5.5e-50 169.6 7.3 1.6 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 CRK26801.1 - 2.2e-26 90.3 43.5 1.9e-05 25.1 0.6 14.0 4 2 13 17 17 17 8 Tetratricopeptide repeat TPR_19 PF14559.6 CRK26801.1 - 1.7e-20 73.3 27.9 3.5e-07 30.6 0.9 10.3 7 3 5 13 13 12 5 Tetratricopeptide repeat TPR_8 PF13181.6 CRK26801.1 - 1.2e-09 37.7 1.3 0.029 14.6 0.0 6.7 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 CRK26801.1 - 1.2e-09 37.5 20.4 0.17 12.1 0.0 9.5 11 0 0 11 11 9 3 Tetratricopeptide repeat TPR_17 PF13431.6 CRK26801.1 - 4.9e-09 35.9 7.0 1.5 9.3 0.1 9.2 7 3 2 9 9 8 1 Tetratricopeptide repeat TPR_16 PF13432.6 CRK26801.1 - 8.2e-09 36.0 38.6 0.00086 19.9 1.4 8.3 8 1 1 9 9 8 3 Tetratricopeptide repeat TPR_15 PF13429.6 CRK26801.1 - 2.9e-08 33.3 26.5 0.0022 17.2 4.4 6.8 2 2 5 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 CRK26801.1 - 2.5e-06 27.1 1.4 0.26 11.2 0.1 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 CRK26801.1 - 5.3e-05 22.8 11.1 2.7 7.8 0.1 6.8 8 1 1 9 9 9 2 TPR repeat TPR_21 PF09976.9 CRK26801.1 - 0.00013 21.8 11.8 0.037 13.7 1.3 4.2 2 1 0 3 3 3 2 Tetratricopeptide repeat-like domain NARP1 PF12569.8 CRK26801.1 - 0.00013 21.0 5.6 1.4 7.7 0.0 5.2 3 1 1 5 5 5 2 NMDA receptor-regulated protein 1 TPR_9 PF13371.6 CRK26801.1 - 0.0016 18.6 12.6 0.02 15.1 0.1 6.0 5 1 1 6 6 6 1 Tetratricopeptide repeat Wzy_C_2 PF11846.8 CRK26801.1 - 0.0038 17.2 3.1 1.4 8.8 0.1 3.9 3 1 0 4 4 4 1 Virulence factor membrane-bound polymerase, C-terminal ZNRF_3_ecto PF18212.1 CRK26801.1 - 0.0043 17.0 2.0 3.9 7.5 0.0 4.9 5 1 0 5 5 4 1 ZNRF-3 Ectodomain ANAPC3 PF12895.7 CRK26801.1 - 0.018 15.2 1.5 12 6.2 0.1 4.5 3 1 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 CRK26801.1 - 0.32 11.7 19.6 60 4.6 0.0 9.0 13 0 0 13 13 9 0 Tetratricopeptide repeat Suf PF05843.14 CRK26801.1 - 0.58 10.1 2.1 63 3.4 0.0 4.0 4 1 1 5 5 5 0 Suppressor of forked protein (Suf) TPR_12 PF13424.6 CRK26801.1 - 2.4 8.5 11.2 27 5.1 0.3 6.1 8 2 0 8 8 6 0 Tetratricopeptide repeat ChAPs PF09295.10 CRK26801.1 - 7.7 5.4 5.9 12 4.8 0.1 3.0 2 1 1 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) V-ATPase_G_2 PF16999.5 CRK26802.1 - 0.13 12.6 7.4 0.085 13.3 2.5 2.1 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit YdfA_immunity PF12127.8 CRK26802.1 - 6.5 5.7 9.5 0.37 9.8 4.3 1.5 2 0 0 2 2 2 0 SigmaW regulon antibacterial ATP-synt_B PF00430.18 CRK26802.1 - 9.4 6.3 15.7 2.6 8.1 11.9 1.8 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) Pex24p PF06398.11 CRK26803.1 - 3.6 6.5 15.3 5.8 5.8 15.3 1.3 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin PPR_2 PF13041.6 CRK26804.1 - 3.7e-05 23.8 0.0 0.16 12.2 0.0 2.7 2 0 0 2 2 2 2 PPR repeat family PPR_3 PF13812.6 CRK26804.1 - 0.023 14.8 0.0 0.051 13.7 0.0 1.6 1 0 0 1 1 1 0 Pentatricopeptide repeat domain SR-25 PF10500.9 CRK26804.1 - 7.1 6.2 11.7 6.5 6.3 5.9 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein PP2C PF00481.21 CRK26805.1 - 1.6e-83 280.3 0.0 2.8e-83 279.5 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C He_PIG PF05345.12 CRK26806.1 - 2e-34 117.5 31.0 1.7e-05 24.9 0.4 7.5 6 0 0 6 6 6 6 Putative Ig domain DUF4448 PF14610.6 CRK26806.1 - 1e-08 35.2 0.0 0.0033 17.2 0.0 2.8 3 0 0 3 3 2 2 Protein of unknown function (DUF4448) DUF4349 PF14257.6 CRK26806.1 - 7.2e-05 22.3 0.1 0.29 10.6 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4349) TMEM154 PF15102.6 CRK26806.1 - 0.00013 21.9 3.4 0.13 12.2 0.0 3.2 3 0 0 3 3 2 2 TMEM154 protein family LptF_LptG PF03739.14 CRK26806.1 - 0.0023 16.9 1.8 1.2 7.9 0.1 2.6 2 0 0 2 2 2 2 Lipopolysaccharide export system permease LptF/LptG BatD PF13584.6 CRK26806.1 - 0.0068 15.3 0.0 2 7.1 0.0 2.4 2 0 0 2 2 2 2 Oxygen tolerance VHL PF01847.16 CRK26806.1 - 0.0074 16.2 0.1 2.3 8.2 0.0 2.7 2 0 0 2 2 2 1 VHL beta domain EphA2_TM PF14575.6 CRK26806.1 - 0.012 16.4 0.0 11 7.0 0.0 2.6 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain MLANA PF14991.6 CRK26806.1 - 0.016 15.5 0.0 7.6 6.9 0.0 2.5 2 0 0 2 2 2 0 Protein melan-A MerT PF02411.15 CRK26806.1 - 0.038 14.0 0.4 13 5.9 0.0 2.3 2 0 0 2 2 2 0 MerT mercuric transport protein NeA_P2 PF12312.8 CRK26806.1 - 0.04 13.4 0.9 10 5.5 0.1 2.7 2 0 0 2 2 2 0 Nepovirus subgroup A polyprotein PqiA PF04403.13 CRK26806.1 - 0.053 13.4 0.3 14 5.5 0.0 2.3 2 0 0 2 2 2 0 Paraquat-inducible protein A Stevor PF17410.2 CRK26806.1 - 0.16 11.5 0.0 20 4.6 0.0 2.2 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame SKG6 PF08693.10 CRK26806.1 - 1 8.8 25.8 0.025 14.0 0.5 3.7 4 0 0 4 4 3 0 Transmembrane alpha-helix domain TrbE PF11100.8 CRK26806.1 - 2 8.7 3.9 42 4.5 0.3 2.5 2 0 0 2 2 2 0 Conjugal transfer protein TrbE BACON PF13004.7 CRK26806.1 - 3.6 7.6 36.0 0.21 11.6 0.9 7.2 8 0 0 8 8 7 0 Putative binding domain, N-terminal Adeno_E3_CR2 PF02439.15 CRK26806.1 - 3.8 7.3 6.5 23 4.9 0.7 2.5 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 TPPK_C PF12555.8 CRK26806.1 - 9.2 6.4 8.3 27 4.9 1.1 2.6 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal Methyltransf_16 PF10294.9 CRK26807.1 - 0.0015 18.3 0.0 0.0018 18.1 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_16 PF10294.9 CRK26808.1 - 1.4e-19 70.5 0.0 1.8e-19 70.1 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase TFIIIC_sub6 PF10419.9 CRK26809.1 - 1.8e-20 72.6 0.0 2.8e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain CBM_4_9 PF02018.17 CRK26809.1 - 0.15 12.3 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain BSP_II PF05432.11 CRK26809.1 - 0.38 10.4 8.5 0.78 9.4 8.5 1.5 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) GRP PF07172.11 CRK26809.1 - 1.5 9.6 14.0 3 8.6 6.6 2.5 2 0 0 2 2 2 0 Glycine rich protein family TFIIIC_sub6 PF10419.9 CRK26811.1 - 6.8e-23 80.4 0.0 9.2e-23 79.9 0.0 1.2 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain BSP_II PF05432.11 CRK26811.1 - 0.012 15.3 5.7 0.015 15.0 5.7 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Pox_Ag35 PF03286.14 CRK26811.1 - 0.14 11.9 2.0 0.22 11.3 2.0 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein NOA36 PF06524.12 CRK26811.1 - 0.27 10.5 4.0 0.38 10.0 4.0 1.2 1 0 0 1 1 1 0 NOA36 protein PBP1_TM PF14812.6 CRK26811.1 - 0.81 10.1 8.1 1.4 9.3 8.1 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal His_biosynth PF00977.21 CRK26812.1 - 7.3e-48 163.0 0.1 3.1e-47 161.0 0.1 2.0 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 CRK26812.1 - 2.8e-21 76.1 0.0 4.3e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 CRK26812.1 - 4.9e-07 29.8 0.0 2.6e-05 24.2 0.0 2.2 2 0 0 2 2 2 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 CRK26812.1 - 7.4e-07 29.0 0.0 2e-06 27.5 0.0 1.7 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain NMO PF03060.15 CRK26812.1 - 0.028 13.8 0.5 0.078 12.3 0.1 1.8 2 0 0 2 2 2 0 Nitronate monooxygenase Dus PF01207.17 CRK26812.1 - 0.031 13.4 0.1 0.075 12.1 0.0 1.6 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) Peptidase_C26 PF07722.13 CRK26812.1 - 0.033 13.9 0.2 0.39 10.4 0.0 2.2 2 0 0 2 2 2 0 Peptidase C26 DDE_Tnp_Tn3 PF01526.17 CRK26812.1 - 0.22 10.2 0.0 0.33 9.7 0.0 1.2 1 0 0 1 1 1 0 Tn3 transposase DDE domain ODC_AZ PF02100.17 CRK26813.1 - 1.3e-26 92.8 0.6 1.4e-26 92.7 0.6 1.0 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme His_biosynth PF00977.21 CRK26814.1 - 4.8e-25 88.4 0.0 5.8e-25 88.1 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein Dus PF01207.17 CRK26814.1 - 0.0078 15.3 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) NMO PF03060.15 CRK26814.1 - 0.0097 15.3 0.1 0.013 15.0 0.1 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase Pantoate_transf PF02548.15 CRK26814.1 - 0.039 13.3 0.0 0.065 12.6 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate hydroxymethyltransferase SOR_SNZ PF01680.17 CRK26814.1 - 0.053 13.3 0.0 0.078 12.8 0.0 1.2 1 0 0 1 1 1 0 SOR/SNZ family ODC_AZ PF02100.17 CRK26815.1 - 9.4e-46 154.5 1.2 1.6e-45 153.7 0.5 1.7 2 0 0 2 2 2 1 Ornithine decarboxylase antizyme Sdh5 PF03937.16 CRK26816.1 - 1.1e-21 76.6 0.1 5.1e-21 74.4 0.1 1.9 2 0 0 2 2 2 1 Flavinator of succinate dehydrogenase Yippee-Mis18 PF03226.14 CRK26819.1 - 6.2e-19 68.2 0.0 8.7e-19 67.7 0.0 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 CRK26819.1 - 0.00021 21.5 0.1 0.0011 19.2 0.0 1.9 2 0 0 2 2 2 1 C-terminal domain of RIG-I zf-C3HC PF07967.13 CRK26819.1 - 0.061 13.4 0.1 4.8 7.2 0.1 2.2 2 0 0 2 2 2 0 C3HC zinc finger-like DUF678 PF05077.12 CRK26819.1 - 0.07 13.3 1.1 6.9 6.9 0.3 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF678) Peptidase_M20 PF01546.28 CRK26821.1 - 1.7e-20 73.6 0.0 1.3e-12 47.8 0.0 2.1 2 0 0 2 2 2 2 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CRK26821.1 - 8.2e-13 48.2 0.0 1.4e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain AnfO_nitrog PF09582.10 CRK26821.1 - 0.0055 16.1 4.3 0.47 9.8 0.6 2.2 2 0 0 2 2 2 2 Iron only nitrogenase protein AnfO (AnfO_nitrog) GATase_3 PF07685.14 CRK26821.1 - 0.12 12.0 0.0 10 5.6 0.0 3.3 4 0 0 4 4 4 0 CobB/CobQ-like glutamine amidotransferase domain F-box_4 PF15966.5 CRK26821.1 - 3 7.8 9.1 35 4.3 1.3 3.2 3 0 0 3 3 3 0 F-box DWNN PF08783.11 CRK26822.1 - 2.5e-22 78.9 0.0 6.2e-22 77.7 0.0 1.7 1 0 0 1 1 1 1 DWNN domain Yippee-Mis18 PF03226.14 CRK26822.1 - 1.7e-17 63.5 0.0 4e-17 62.4 0.0 1.6 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly His_biosynth PF00977.21 CRK26822.1 - 2.8e-14 53.1 0.1 6.8e-14 51.9 0.0 1.7 2 0 0 2 2 2 1 Histidine biosynthesis protein Peptidase_M20 PF01546.28 CRK26823.1 - 7.1e-24 84.7 0.0 9e-24 84.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DWNN PF08783.11 CRK26824.1 - 2.4e-31 107.8 0.0 4.1e-31 107.1 0.0 1.4 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 CRK26824.1 - 8.9e-09 35.0 5.5 1.3e-08 34.4 5.5 1.3 1 0 0 1 1 1 1 Zinc knuckle Med3 PF11593.8 CRK26824.1 - 0.00026 20.3 42.8 0.00026 20.3 42.8 2.1 2 0 0 2 2 2 1 Mediator complex subunit 3 fungal zf-CCHC PF00098.23 CRK26824.1 - 0.0006 19.8 0.9 0.00095 19.1 0.9 1.3 1 0 0 1 1 1 1 Zinc knuckle Keratin_2_head PF16208.5 CRK26824.1 - 2.1 8.5 20.7 4.8 7.3 20.7 1.6 1 0 0 1 1 1 0 Keratin type II head ArsA_ATPase PF02374.15 CRK26825.1 - 3.3e-85 285.9 2.8 1.6e-64 218.0 0.0 2.0 1 1 1 2 2 2 2 Anion-transporting ATPase AAA_31 PF13614.6 CRK26825.1 - 2e-15 57.2 0.0 1.9e-14 54.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 CRK26825.1 - 5.9e-13 49.0 0.0 1e-12 48.2 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 CRK26825.1 - 2.4e-06 27.2 0.0 3.8e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.22 CRK26825.1 - 4.4e-06 26.5 0.5 0.00029 20.5 0.0 2.6 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain CBP_BcsQ PF06564.12 CRK26825.1 - 2.4e-05 24.0 0.0 6.4e-05 22.5 0.0 1.6 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ ParA PF10609.9 CRK26825.1 - 8.5e-05 22.1 0.8 8.5e-05 22.1 0.8 2.6 3 1 1 4 4 4 1 NUBPL iron-transfer P-loop NTPase PhoH PF02562.16 CRK26825.1 - 0.021 14.3 0.0 0.067 12.6 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA_25 PF13481.6 CRK26825.1 - 0.022 14.4 0.0 0.071 12.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CRK26825.1 - 0.031 14.6 0.0 0.047 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 CRK26825.1 - 0.04 13.1 0.0 0.065 12.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.6 CRK26825.1 - 0.096 13.2 0.2 0.38 11.3 0.1 2.0 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 CRK26825.1 - 0.11 12.4 0.6 0.44 10.4 0.1 2.1 2 0 0 2 2 2 0 NACHT domain Tir_receptor_N PF07490.11 CRK26825.1 - 0.11 12.3 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus Zeta_toxin PF06414.12 CRK26825.1 - 0.12 11.7 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin MipZ PF09140.11 CRK26825.1 - 0.12 11.7 0.2 0.24 10.6 0.1 1.6 1 1 0 1 1 1 0 ATPase MipZ VirC1 PF07015.11 CRK26825.1 - 0.13 11.5 0.2 0.31 10.3 0.0 1.6 2 0 0 2 2 2 0 VirC1 protein IstB_IS21 PF01695.17 CRK26825.1 - 0.13 11.9 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 CRK26825.1 - 0.17 11.6 0.2 0.64 9.7 0.1 1.9 2 1 0 2 2 1 0 AAA domain Ndc1_Nup PF09531.10 CRK26827.1 - 0.08 11.6 1.0 0.07 11.8 1.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ArsA_ATPase PF02374.15 CRK26828.1 - 5.7e-113 377.1 0.1 6.6e-113 376.9 0.1 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 CRK26828.1 - 2.5e-15 56.8 0.2 2.8e-14 53.4 0.0 2.2 2 1 0 2 2 2 1 AAA domain CbiA PF01656.23 CRK26828.1 - 5.7e-13 49.0 0.0 1e-12 48.2 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 CRK26828.1 - 2.2e-06 27.3 0.0 5.1e-06 26.1 0.0 1.6 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.22 CRK26828.1 - 6.7e-06 25.9 0.5 0.00037 20.2 0.0 2.7 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain CBP_BcsQ PF06564.12 CRK26828.1 - 3.2e-05 23.5 0.0 8.3e-05 22.2 0.0 1.6 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ ParA PF10609.9 CRK26828.1 - 6e-05 22.6 6.6 0.00011 21.7 0.8 3.1 3 1 1 4 4 4 1 NUBPL iron-transfer P-loop NTPase PhoH PF02562.16 CRK26828.1 - 0.029 13.8 0.0 0.086 12.3 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA_25 PF13481.6 CRK26828.1 - 0.029 13.9 0.0 0.099 12.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CRK26828.1 - 0.039 14.3 0.0 0.067 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 CRK26828.1 - 0.047 12.9 0.0 0.084 12.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain FIST_C PF10442.9 CRK26828.1 - 0.13 12.3 0.0 0.34 10.9 0.0 1.8 1 1 0 1 1 1 0 FIST C domain Tir_receptor_N PF07490.11 CRK26828.1 - 0.14 12.0 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus Pex24p PF06398.11 CRK26828.1 - 0.14 11.1 0.1 0.23 10.4 0.1 1.2 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Zeta_toxin PF06414.12 CRK26828.1 - 0.15 11.3 0.0 0.29 10.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.6 CRK26828.1 - 0.15 12.6 0.1 0.52 10.9 0.1 2.0 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 CRK26828.1 - 0.16 11.7 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein MipZ PF09140.11 CRK26828.1 - 0.16 11.2 0.2 0.32 10.2 0.2 1.6 1 1 0 1 1 1 0 ATPase MipZ AAA_24 PF13479.6 CRK26828.1 - 0.18 11.5 0.1 0.91 9.2 0.1 2.2 2 1 0 2 2 2 0 AAA domain ATPase PF06745.13 CRK26828.1 - 0.19 11.1 0.3 0.82 9.0 0.0 2.0 2 1 1 3 3 3 0 KaiC NACHT PF05729.12 CRK26828.1 - 0.19 11.6 0.9 0.58 10.0 0.1 2.1 2 0 0 2 2 2 0 NACHT domain SUR7 PF06687.12 CRK26830.1 - 7.4e-20 71.5 4.6 7.4e-20 71.5 4.6 1.4 1 1 0 1 1 1 1 SUR7/PalI family PsbX PF06596.11 CRK26830.1 - 0.025 14.6 0.9 0.025 14.6 0.9 3.2 4 0 0 4 4 4 0 Photosystem II reaction centre X protein (PsbX) Trp_oprn_chp PF09534.10 CRK26830.1 - 0.049 13.4 1.6 0.067 13.0 0.1 1.9 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) LYRIC PF15686.5 CRK26830.1 - 0.085 12.4 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family DUF4223 PF13978.6 CRK26830.1 - 0.16 12.0 0.8 0.6 10.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4223) Tmemb_170 PF10190.9 CRK26830.1 - 0.5 10.7 7.7 0.62 10.4 0.1 3.0 3 0 0 3 3 3 0 Putative transmembrane protein 170 DUF5527 PF17665.1 CRK26830.1 - 1.2 8.7 3.5 0.3 10.6 0.1 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5527) Transthyretin PF00576.21 CRK26832.1 - 1.8e-16 60.8 0.0 3.3e-16 59.9 0.0 1.4 1 1 0 1 1 1 1 HIUase/Transthyretin family FAD_binding_8 PF08022.12 CRK26833.1 - 1.1e-17 64.0 0.0 2.6e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 CRK26833.1 - 8.8e-12 45.2 2.5 2.1e-11 44.0 2.5 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 CRK26833.1 - 1.1e-06 28.9 6.2 0.00013 22.2 2.8 3.1 1 1 0 2 2 2 2 Ferric reductase NAD binding domain EF-hand_7 PF13499.6 CRK26833.1 - 0.0044 17.4 3.1 0.0086 16.5 1.7 2.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CRK26833.1 - 0.057 13.4 1.1 0.15 12.0 1.1 1.7 1 0 0 1 1 1 0 EF-hand domain EF-hand_1 PF00036.32 CRK26833.1 - 0.14 11.7 2.0 0.37 10.5 2.0 1.8 1 0 0 1 1 1 0 EF hand Cu-oxidase_2 PF07731.14 CRK26834.1 - 5.9e-41 139.4 9.6 3.2e-38 130.5 0.2 3.1 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 CRK26834.1 - 9.3e-41 138.6 7.8 1.2e-39 134.9 4.4 3.5 3 1 1 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.22 CRK26834.1 - 3.4e-34 118.3 0.1 1.4e-33 116.3 0.0 2.0 2 0 0 2 2 2 1 Multicopper oxidase NAD_binding_6 PF08030.12 CRK26835.1 - 1.3e-12 48.1 1.1 6.9e-11 42.5 1.1 3.1 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ureidogly_lyase PF04115.12 CRK26836.1 - 7.5e-55 185.6 0.0 1.3e-54 184.9 0.0 1.3 1 0 0 1 1 1 1 Ureidoglycolate lyase Cu-oxidase_3 PF07732.15 CRK26836.1 - 4.9e-41 139.5 6.4 2.9e-40 137.0 3.3 3.3 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 CRK26836.1 - 2.3e-40 137.5 12.9 7.6e-39 132.6 0.2 3.4 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 CRK26836.1 - 5.8e-36 124.0 0.3 2e-35 122.3 0.0 2.0 3 0 0 3 3 3 1 Multicopper oxidase DnaJ PF00226.31 CRK26838.1 - 4.4e-11 42.7 0.0 6.7e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain MFS_1 PF07690.16 CRK26840.1 - 2.3e-31 109.0 49.0 7.3e-28 97.5 30.5 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK26840.1 - 2e-21 76.4 21.8 5.6e-19 68.3 6.6 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter DUF21 PF01595.20 CRK26840.1 - 0.67 9.6 6.0 2.6 7.7 0.1 3.5 3 1 0 3 3 3 0 Cyclin M transmembrane N-terminal domain Adeno_terminal PF02459.15 CRK26842.1 - 0.033 12.6 2.6 0.062 11.7 2.6 1.3 1 0 0 1 1 1 0 Adenoviral DNA terminal protein CDC27 PF09507.10 CRK26842.1 - 0.094 12.1 9.6 0.082 12.3 8.2 1.5 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 BUD22 PF09073.10 CRK26842.1 - 4.2 6.6 15.2 6.3 6.0 15.2 1.2 1 0 0 1 1 1 0 BUD22 MRC1 PF09444.10 CRK26844.1 - 5.6e-42 143.7 22.3 5.6e-42 143.7 22.3 6.3 6 1 1 7 7 7 1 MRC1-like domain K_channel_TID PF07941.11 CRK26844.1 - 2.4 8.7 6.3 30 5.2 0.8 3.5 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain MFS_1 PF07690.16 CRK26845.1 - 1e-24 87.1 38.4 3.4e-19 69.0 11.6 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily MRC1 PF09444.10 CRK26847.1 - 8.9e-42 143.1 21.1 8.9e-42 143.1 21.1 6.1 5 1 1 6 6 6 1 MRC1-like domain Cytochrom_B561 PF03188.16 CRK26847.1 - 0.0001 22.4 0.1 0.00022 21.4 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 FA_desaturase PF00487.24 CRK26847.1 - 0.063 13.1 0.4 0.1 12.4 0.4 1.2 1 0 0 1 1 1 0 Fatty acid desaturase MFS_1 PF07690.16 CRK26849.1 - 6.7e-21 74.6 51.1 7.2e-17 61.3 15.1 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily CDH-cyt PF16010.5 CRK26851.1 - 1e-17 64.4 0.0 1.7e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 CRK26851.1 - 1.3e-09 38.3 9.2 1.3e-09 38.3 9.2 1.8 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF2427 PF10348.9 CRK26851.1 - 1.2e-06 28.2 1.9 1.2e-06 28.2 1.9 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) Bax1-I PF01027.20 CRK26851.1 - 0.038 13.8 8.5 0.061 13.2 8.5 1.3 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 DUF4079 PF13301.6 CRK26851.1 - 0.053 13.7 7.8 0.85 9.8 5.9 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) ECF_trnsprt PF12822.7 CRK26851.1 - 0.77 9.8 7.5 2.4 8.2 7.5 2.0 1 1 0 1 1 1 0 ECF transporter, substrate-specific component DUF2157 PF09925.9 CRK26851.1 - 1.6 8.5 11.1 17 5.2 11.1 2.1 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) Transmemb_17 PF09799.9 CRK26851.1 - 2.1 9.0 5.2 2.6 8.7 0.2 2.2 2 0 0 2 2 2 0 Predicted membrane protein COX1 PF00115.20 CRK26851.1 - 2.9 6.7 13.7 5.6e+02 -0.9 13.8 2.1 1 1 0 1 1 1 0 Cytochrome C and Quinol oxidase polypeptide I CPP1-like PF11833.8 CRK26851.1 - 9.4 5.8 5.7 33 4.1 0.6 2.2 1 1 1 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like PMP22_Claudin PF00822.20 CRK26851.1 - 10 6.0 10.7 1.1 9.1 3.6 2.3 1 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family NAD_binding_5 PF07994.12 CRK26855.1 - 1.3e-145 484.8 0.0 1.5e-145 484.6 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 CRK26855.1 - 1.3e-44 150.9 0.4 2.7e-44 149.9 0.4 1.6 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase DUF5049 PF16468.5 CRK26855.1 - 0.047 13.6 0.0 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5049) LIM PF00412.22 CRK26856.1 - 7.7e-43 144.5 42.2 9.2e-12 45.0 5.1 5.1 6 0 0 6 6 6 4 LIM domain AMP-binding PF00501.28 CRK26856.1 - 0.0021 16.7 0.0 0.58 8.7 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme WRC PF08879.10 CRK26856.1 - 0.0028 17.3 5.6 0.81 9.4 0.5 2.7 2 0 0 2 2 2 2 WRC zf-C2H2 PF00096.26 CRK26856.1 - 0.024 15.1 15.4 18 6.0 0.6 5.5 4 0 0 4 4 4 0 Zinc finger, C2H2 type A2L_zn_ribbon PF08792.10 CRK26856.1 - 5.8 6.8 7.6 36 4.2 0.9 3.5 2 0 0 2 2 2 0 A2L zinc ribbon domain zf_C2HC_14 PF18574.1 CRK26856.1 - 5.9 6.8 17.8 5.7 6.8 1.1 4.4 4 0 0 4 4 4 0 C2HC Zing finger domain DUF3405 PF11885.8 CRK26858.1 - 5.3e-186 619.2 2.6 1.1e-185 618.1 2.6 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3405) dCMP_cyt_deam_1 PF00383.23 CRK26860.1 - 4.7e-24 84.2 0.9 7.1e-24 83.6 0.9 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CRK26860.1 - 3e-09 36.7 0.0 5.1e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 MafB19-like deaminase AAA_18 PF13238.6 CRK26860.1 - 0.00057 20.4 0.0 0.0013 19.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain CoaE PF01121.20 CRK26860.1 - 0.0062 16.2 0.0 0.0087 15.8 0.0 1.3 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.6 CRK26860.1 - 0.23 11.9 0.0 0.35 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATG7_N PF16420.5 CRK26862.1 - 2.8e-103 345.7 0.4 3.7e-103 345.3 0.4 1.1 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 CRK26862.1 - 1e-42 146.2 0.0 1.6e-42 145.6 0.0 1.2 1 0 0 1 1 1 1 ThiF family Formyl_trans_N PF00551.19 CRK26862.1 - 4.6e-15 55.8 0.0 1e-14 54.7 0.0 1.5 1 0 0 1 1 1 1 Formyl transferase SNF2_N PF00176.23 CRK26865.1 - 1.1e-12 47.3 2.0 1.3e-11 43.9 0.9 2.6 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CRK26865.1 - 1.7e-06 28.4 0.4 4.8e-06 26.9 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 CRK26865.1 - 0.0037 17.1 3.6 0.0087 15.9 3.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CRK26865.1 - 0.025 14.6 3.8 0.056 13.5 3.8 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Dsh_C PF12316.8 CRK26865.1 - 0.05 14.0 2.7 0.15 12.5 2.7 1.8 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal zf-C3HC4_3 PF13920.6 CRK26865.1 - 0.07 13.0 5.3 0.15 11.9 5.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CRK26865.1 - 0.11 12.4 6.6 0.27 11.1 6.6 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CRK26865.1 - 0.24 11.4 6.2 0.5 10.4 6.2 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 CRK26865.1 - 0.37 11.2 6.3 0.88 10.0 6.3 1.6 1 0 0 1 1 1 0 Ring finger domain DUF3405 PF11885.8 CRK26867.1 - 2.1e-195 650.3 1.8 2.1e-195 650.3 1.8 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3405) dCMP_cyt_deam_1 PF00383.23 CRK26869.1 - 4.7e-24 84.2 0.9 7.1e-24 83.6 0.9 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CRK26869.1 - 3e-09 36.7 0.0 5.1e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 MafB19-like deaminase AAA_18 PF13238.6 CRK26869.1 - 0.00023 21.7 0.0 0.00042 20.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain CoaE PF01121.20 CRK26869.1 - 0.007 16.1 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.6 CRK26869.1 - 0.25 11.8 0.0 0.44 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATG7_N PF16420.5 CRK26870.1 - 6.6e-103 344.5 0.3 8.8e-103 344.1 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 CRK26870.1 - 5.4e-43 147.1 0.0 8.7e-43 146.4 0.0 1.2 1 0 0 1 1 1 1 ThiF family Formyl_trans_N PF00551.19 CRK26870.1 - 7.5e-18 64.9 0.0 1.4e-17 64.0 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase SNF2_N PF00176.23 CRK26873.1 - 1.7e-38 132.2 0.1 4.8e-26 91.3 0.1 3.4 2 1 0 2 2 2 2 SNF2 family N-terminal domain DNA_methylase PF00145.17 CRK26873.1 - 2.5e-16 59.9 0.0 1.6e-05 24.4 0.0 4.7 4 0 0 4 4 4 3 C-5 cytosine-specific DNA methylase ResIII PF04851.15 CRK26873.1 - 3.2e-09 37.0 0.0 0.00023 21.2 0.0 3.2 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 CRK26873.1 - 0.0098 15.7 4.4 0.028 14.3 4.4 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CRK26873.1 - 0.053 13.6 4.6 0.13 12.3 4.6 1.8 1 0 0 1 1 1 0 RING-type zinc-finger IBR PF01485.21 CRK26873.1 - 0.067 13.4 26.2 0.079 13.2 2.5 3.9 3 1 1 4 4 4 0 IBR domain, a half RING-finger domain Prok-RING_4 PF14447.6 CRK26873.1 - 0.43 10.5 5.8 1.4 8.8 5.8 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CRK26873.1 - 0.5 10.4 6.9 2.1 8.4 6.9 2.1 1 0 0 1 1 1 0 zinc-RING finger domain FeThRed_B PF02943.15 CRK26873.1 - 1.8 8.6 3.8 40 4.3 0.2 2.9 2 0 0 2 2 2 0 Ferredoxin thioredoxin reductase catalytic beta chain CTP_transf_like PF01467.26 CRK26875.1 - 0.042 14.1 0.1 0.1 12.8 0.1 1.6 1 0 0 1 1 1 0 Cytidylyltransferase-like DUF3405 PF11885.8 CRK26877.1 - 4.1e-209 695.5 3.0 1.8e-208 693.4 3.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3405) zf-RING_UBOX PF13445.6 CRK26878.1 - 8.3e-08 32.1 1.4 8.3e-08 32.1 1.4 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CRK26878.1 - 2.3e-07 30.5 5.2 4.3e-07 29.7 5.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CRK26878.1 - 4.4e-07 29.7 4.3 8.7e-07 28.7 4.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CRK26878.1 - 2.1e-06 28.0 5.3 4.4e-06 26.9 5.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 CRK26878.1 - 2.4e-06 27.4 3.7 4.6e-06 26.5 3.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CRK26878.1 - 3e-06 27.0 4.7 1.1e-05 25.2 1.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CRK26878.1 - 2.4e-05 24.4 4.9 0.0002 21.5 5.1 2.1 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 CRK26878.1 - 0.0063 16.4 8.7 0.04 13.8 8.6 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-MIZ PF02891.20 CRK26878.1 - 0.13 12.0 5.2 9.8 6.0 6.1 2.4 1 1 1 2 2 2 0 MIZ/SP-RING zinc finger zf-rbx1 PF12678.7 CRK26878.1 - 0.44 10.9 4.2 1.4 9.3 4.2 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_10 PF16685.5 CRK26878.1 - 0.93 9.7 5.7 2.8 8.1 5.7 1.8 1 1 0 1 1 1 0 zinc RING finger of MSL2 zf-ribbon_3 PF13248.6 CRK26878.1 - 1.9 8.0 4.3 3.8 7.1 0.7 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Lar_restr_allev PF14354.6 CRK26878.1 - 4.5 7.7 5.9 8.8 6.8 1.5 2.5 1 1 1 2 2 2 0 Restriction alleviation protein Lar DHO_dh PF01180.21 CRK26881.1 - 2.2e-22 79.6 0.0 1.4e-21 77.0 0.0 1.8 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase NMO PF03060.15 CRK26881.1 - 0.037 13.4 0.6 0.054 12.9 0.6 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase K_oxygenase PF13434.6 CRK26882.1 - 4.4e-07 29.4 0.0 0.01 15.0 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 CRK26882.1 - 0.00018 20.9 0.1 0.3 10.3 0.0 2.6 2 2 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CRK26882.1 - 0.00024 20.5 0.0 0.0082 15.4 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 CRK26882.1 - 0.013 15.5 0.2 0.059 13.3 0.1 2.2 2 1 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 CRK26882.1 - 0.027 14.7 0.1 0.43 10.8 0.0 2.9 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CRK26882.1 - 0.032 13.5 0.0 0.058 12.6 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 CRK26882.1 - 0.037 13.3 0.1 0.18 11.0 0.1 2.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CRK26882.1 - 0.047 12.7 0.0 0.078 12.0 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein DAO PF01266.24 CRK26882.1 - 0.16 11.5 1.6 1.8 8.0 0.1 2.8 3 1 0 3 3 3 0 FAD dependent oxidoreductase MDM10 PF12519.8 CRK26883.1 - 2.2e-116 389.5 0.0 2.3e-104 349.9 0.0 2.2 1 1 1 2 2 2 2 Mitochondrial distribution and morphology protein 10 DUF3446 PF11928.8 CRK26883.1 - 0.027 14.8 4.3 0.027 14.8 4.3 1.9 2 0 0 2 2 2 0 Early growth response N-terminal domain HR1 PF02185.16 CRK26883.1 - 0.081 13.1 0.7 0.2 11.8 0.7 1.6 1 0 0 1 1 1 0 Hr1 repeat TRAF_BIRC3_bd PF16673.5 CRK26883.1 - 0.13 12.0 0.8 0.24 11.2 0.8 1.3 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain SR-25 PF10500.9 CRK26883.1 - 1.7 8.2 6.1 4.7 6.8 6.1 1.7 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Zip PF02535.22 CRK26884.1 - 4.2e-56 190.6 7.7 5.1e-56 190.3 7.7 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Ribosomal_S19e PF01090.19 CRK26885.1 - 1.1e-54 183.8 0.1 2.3e-54 182.8 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S19e Git3 PF11710.8 CRK26885.1 - 1.7e-17 63.9 8.3 3.7e-17 62.8 8.3 1.5 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 CRK26885.1 - 4.7e-08 32.7 0.0 7.4e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Dicty_CAR PF05462.11 CRK26885.1 - 0.00016 20.9 2.2 0.0044 16.2 1.4 2.2 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor GPR_Gpa2_C PF11970.8 CRK26885.1 - 0.0051 16.9 0.0 0.0051 16.9 0.0 2.2 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term CbiQ PF02361.16 CRK26885.1 - 0.051 13.2 3.8 0.11 12.1 3.8 1.5 1 0 0 1 1 1 0 Cobalt transport protein DC_STAMP PF07782.13 CRK26886.1 - 0.0042 16.9 0.0 0.0043 16.9 0.0 1.0 1 0 0 1 1 1 1 DC-STAMP-like protein Fungal_trans PF04082.18 CRK26887.1 - 1.2e-11 44.2 0.1 2.5e-11 43.1 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 CRK26887.1 - 1.8e-06 28.1 11.3 0.01 16.2 0.8 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CRK26887.1 - 0.00079 20.1 7.9 0.4 11.7 2.2 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger 2TM PF13239.6 CRK26888.1 - 0.23 11.8 0.2 0.23 11.8 0.2 2.0 2 1 0 2 2 2 0 2TM domain Peptidase_C2 PF00648.21 CRK26893.1 - 1.4e-18 67.0 0.0 2.8e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 Calpain family cysteine protease LysM PF01476.20 CRK26894.1 - 9.4e-09 35.2 0.0 0.00025 21.1 0.1 3.8 5 0 0 5 5 5 2 LysM domain L51_S25_CI-B8 PF05047.16 CRK26894.1 - 0.42 10.6 1.0 1.4 8.9 0.0 2.2 3 0 0 3 3 3 0 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Pkinase PF00069.25 CRK26895.1 - 9.3e-19 67.8 0.0 4e-18 65.7 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Ank_3 PF13606.6 CRK26895.1 - 4e-06 26.7 0.5 0.24 12.1 0.0 4.7 5 0 0 5 5 5 2 Ankyrin repeat Pkinase_Tyr PF07714.17 CRK26895.1 - 2.7e-05 23.6 0.0 5.8e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.7 CRK26895.1 - 0.00014 22.4 0.0 0.5 11.0 0.0 3.4 2 2 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CRK26895.1 - 0.00063 20.3 0.1 0.53 10.9 0.0 4.4 5 0 0 5 5 5 1 Ankyrin repeats (many copies) Ank PF00023.30 CRK26895.1 - 0.0084 16.5 0.3 0.43 11.1 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat AMPK1_CBM PF16561.5 CRK26896.1 - 1e-20 73.7 0.9 2e-20 72.8 0.9 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM53 PF16760.5 CRK26896.1 - 0.013 16.1 0.4 0.028 15.0 0.4 1.5 1 0 0 1 1 1 0 Starch/carbohydrate-binding module (family 53) CBM_48 PF02922.18 CRK26896.1 - 0.072 13.5 0.1 0.15 12.5 0.1 1.4 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Porin_5 PF16930.5 CRK26896.1 - 0.47 8.9 8.9 0.97 7.8 8.9 1.6 1 0 0 1 1 1 0 Putative porin Sugar_tr PF00083.24 CRK26897.1 - 2.9e-94 316.5 17.6 3.7e-94 316.1 17.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK26897.1 - 1.2e-18 67.2 33.7 6e-11 41.9 11.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Gal11_ABD1 PF18535.1 CRK26897.1 - 0.95 9.6 3.3 0.39 10.8 0.3 1.8 2 0 0 2 2 2 0 Gal11 activator-binding domain (ABD1) Na_Ca_ex PF01699.24 CRK26897.1 - 5.7 6.9 12.4 3.9 7.4 1.1 2.7 3 0 0 3 3 3 0 Sodium/calcium exchanger protein Peptidase_C12 PF01088.21 CRK26898.1 - 7.4e-54 182.7 0.0 1.5e-53 181.7 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Peptidase_M24 PF00557.24 CRK26898.1 - 1.6e-52 178.2 0.0 2.5e-52 177.6 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 CRK26898.1 - 2.1e-25 88.9 0.0 5.2e-25 87.6 0.0 1.6 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Glyoxalase PF00903.25 CRK26898.1 - 0.026 14.7 0.0 0.065 13.4 0.0 1.7 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily PseudoU_synth_1 PF01416.20 CRK26899.1 - 6.8e-10 39.4 0.0 9.4e-09 35.7 0.0 2.5 2 0 0 2 2 2 1 tRNA pseudouridine synthase T3SS_needle_F PF09392.10 CRK26899.1 - 0.42 10.8 1.8 0.75 10.0 0.1 2.3 2 0 0 2 2 2 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF Med22 PF06179.12 CRK26900.1 - 4.5e-18 65.4 0.6 6.2e-18 64.9 0.6 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex CBM_1 PF00734.18 CRK26903.1 - 4.8e-12 45.6 16.3 1.3e-11 44.2 16.3 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain Peptidase_S9 PF00326.21 CRK26903.1 - 0.00058 19.4 0.1 0.0012 18.4 0.1 1.5 2 0 0 2 2 2 1 Prolyl oligopeptidase family Esterase_phd PF10503.9 CRK26903.1 - 0.00079 19.0 0.2 0.0067 15.9 0.1 2.1 1 1 1 2 2 2 1 Esterase PHB depolymerase Abhydrolase_2 PF02230.16 CRK26903.1 - 0.022 14.6 0.0 0.033 14.0 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Esterase PF00756.20 CRK26903.1 - 0.023 14.4 0.1 0.094 12.3 0.1 2.0 1 1 0 1 1 1 0 Putative esterase Toxin_7 PF05980.12 CRK26903.1 - 3.5 8.0 11.2 6.9 7.0 10.5 1.9 2 0 0 2 2 2 0 Toxin 7 Patatin PF01734.22 CRK26904.1 - 2.6e-21 76.7 0.0 1.1e-20 74.7 0.0 2.1 1 1 0 1 1 1 1 Patatin-like phospholipase NB-ARC PF00931.22 CRK26904.1 - 1.9e-09 37.1 0.0 4e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 CRK26904.1 - 2.1e-06 28.0 0.0 1.5e-05 25.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CRK26904.1 - 0.00039 20.9 1.1 0.0016 18.9 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain AAA_25 PF13481.6 CRK26904.1 - 0.00077 19.1 0.1 0.003 17.2 0.0 1.9 1 1 1 2 2 2 1 AAA domain TPR_4 PF07721.14 CRK26904.1 - 0.0029 18.1 3.4 10 7.1 0.0 4.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 CRK26904.1 - 0.02 15.2 2.5 5.5 7.4 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat AAA_14 PF13173.6 CRK26904.1 - 0.037 14.1 0.0 0.52 10.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain CbiA PF01656.23 CRK26904.1 - 0.046 13.8 0.0 0.21 11.7 0.0 1.9 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain NACHT PF05729.12 CRK26904.1 - 0.068 13.1 0.1 0.18 11.7 0.1 1.7 1 1 0 1 1 1 0 NACHT domain SurA_N_2 PF13623.6 CRK26904.1 - 0.59 10.0 3.1 21 4.9 1.9 2.4 2 0 0 2 2 2 0 SurA N-terminal domain DUF4719 PF15843.5 CRK26905.1 - 0.014 15.5 1.3 0.025 14.7 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4719) SelP_N PF04592.14 CRK26905.1 - 1.4 8.3 16.5 2 7.7 16.5 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region TFIIA PF03153.13 CRK26905.1 - 4.1 7.3 12.2 4.7 7.1 12.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RRM_1 PF00076.22 CRK26906.1 - 2.5e-12 46.4 0.1 4.5e-08 32.8 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_pol_Rpc4 PF05132.14 CRK26906.1 - 2.7 8.4 6.5 1.4 9.3 4.2 1.8 2 1 0 2 2 2 0 RNA polymerase III RPC4 Tubulin PF00091.25 CRK26907.1 - 1.3e-63 214.8 0.0 1.7e-63 214.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CRK26907.1 - 7.3e-44 149.0 0.0 1.1e-43 148.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CRK26907.1 - 8.9e-05 22.2 0.0 0.00015 21.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Coiled-coil_56 PF09813.9 CRK26908.1 - 0.00097 19.1 0.0 0.001 19.0 0.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 DUF3453 PF11935.8 CRK26909.1 - 1.5e-68 230.8 0.8 2e-67 227.1 0.9 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3453) HMGL-like PF00682.19 CRK26910.1 - 7.3e-75 251.9 0.0 1.7e-74 250.7 0.0 1.6 2 0 0 2 2 2 1 HMGL-like LeuA_dimer PF08502.10 CRK26910.1 - 5.9e-23 81.2 0.0 1.3e-22 80.2 0.0 1.6 1 1 0 1 1 1 1 LeuA allosteric (dimerisation) domain DUF3450 PF11932.8 CRK26911.1 - 0.025 13.9 1.0 0.025 13.9 1.0 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) Asp PF00026.23 CRK26912.1 - 6e-29 101.5 0.0 4.6e-28 98.6 0.0 2.2 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 CRK26912.1 - 0.0025 18.4 0.3 0.22 12.2 0.0 2.6 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 CRK26912.1 - 0.0067 17.0 0.1 0.67 10.6 0.0 2.6 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 CRK26912.1 - 0.039 14.3 0.0 0.18 12.1 0.0 2.0 2 0 0 2 2 2 0 Retroviral aspartyl protease TAXi_C PF14541.6 CRK26912.1 - 0.053 13.3 0.1 7.6 6.3 0.1 2.9 2 1 0 2 2 2 0 Xylanase inhibitor C-terminal SET PF00856.28 CRK26913.1 - 1.4e-09 38.6 0.2 4.3e-09 37.0 0.0 2.0 2 1 0 2 2 2 1 SET domain zf-MYND PF01753.18 CRK26913.1 - 3.2e-07 30.3 14.0 3.2e-07 30.3 14.0 1.7 2 0 0 2 2 2 1 MYND finger Zn_clus PF00172.18 CRK26914.1 - 2.9e-07 30.5 10.2 5.6e-07 29.6 10.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RRM_1 PF00076.22 CRK26915.1 - 3e-28 97.4 0.1 1e-13 50.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HLH PF00010.26 CRK26915.1 - 6.1e-12 45.3 1.2 1.6e-11 44.0 1.2 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain RRM_5 PF13893.6 CRK26915.1 - 7.3e-05 22.4 0.0 0.0017 17.9 0.0 2.3 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CRK26915.1 - 0.032 14.3 0.3 0.33 11.0 0.1 2.3 2 0 0 2 2 2 0 RNA binding motif RRM_occluded PF16842.5 CRK26915.1 - 0.099 12.5 0.0 5.4 7.0 0.0 2.4 2 0 0 2 2 2 0 Occluded RNA-recognition motif DUF4776 PF16003.5 CRK26915.1 - 0.11 11.4 1.4 0.18 10.8 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) GIT_CC PF16559.5 CRK26915.1 - 0.16 11.9 0.4 0.4 10.6 0.4 1.7 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor TPR_11 PF13414.6 CRK26916.1 - 1.6e-17 62.9 5.2 1.3e-06 28.0 0.1 3.6 2 1 1 3 3 3 3 TPR repeat TPR_1 PF00515.28 CRK26916.1 - 4.6e-16 57.9 3.6 6.2e-08 32.1 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 CRK26916.1 - 5.3e-15 54.8 11.8 2.9e-06 27.6 0.4 4.9 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 CRK26916.1 - 2.8e-14 52.0 12.7 1.2e-06 28.2 0.0 5.4 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 CRK26916.1 - 4.9e-12 45.3 4.8 0.19 12.2 0.0 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 CRK26916.1 - 1.3e-11 44.9 14.3 0.0025 18.4 0.5 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 CRK26916.1 - 1.4e-10 40.5 4.6 1.8e-05 24.6 0.0 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 CRK26916.1 - 3.2e-07 30.8 12.2 0.01 16.4 0.5 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 CRK26916.1 - 3.3e-06 26.7 7.4 0.035 14.1 0.1 5.1 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 CRK26916.1 - 9.9e-06 25.6 5.3 0.00093 19.3 1.3 2.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 CRK26916.1 - 1.2e-05 25.6 8.6 0.32 11.7 0.1 6.0 6 1 0 6 6 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 CRK26916.1 - 1.9e-05 24.8 9.8 0.0086 16.3 0.6 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.6 CRK26916.1 - 0.00092 18.5 9.1 0.012 14.8 1.8 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 CRK26916.1 - 0.037 13.9 5.4 0.058 13.3 0.2 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat BTAD PF03704.17 CRK26916.1 - 0.15 12.5 4.1 3 8.3 0.5 2.7 2 0 0 2 2 2 0 Bacterial transcriptional activator domain CRISPR_Cse2 PF09485.10 CRK26916.1 - 0.15 12.6 1.8 0.91 10.0 0.1 2.5 2 0 0 2 2 2 0 CRISPR-associated protein Cse2 (CRISPR_cse2) ANAPC3 PF12895.7 CRK26916.1 - 0.18 12.1 4.3 6.3 7.1 0.6 3.0 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 CRK26916.1 - 0.3 11.4 11.6 0.086 13.2 0.8 3.8 2 1 2 4 4 4 0 Tetratricopeptide repeat Tim17 PF02466.19 CRK26918.1 - 0.0098 16.3 0.0 0.025 15.0 0.0 1.6 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family MF_alpha_N PF05436.11 CRK26919.1 - 0.23 11.4 0.6 0.72 9.8 0.3 1.9 1 1 1 2 2 2 0 Mating factor alpha precursor N-terminus Methyltransf_PK PF05891.12 CRK26920.1 - 1.8e-65 220.5 0.0 2.1e-65 220.3 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Ribosomal_L21p PF00829.21 CRK26921.1 - 3.7e-10 39.9 0.0 4.9e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Pkinase PF00069.25 CRK26922.1 - 2.4e-44 151.7 0.0 3.7e-44 151.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK26922.1 - 5.9e-18 65.1 0.0 9.1e-18 64.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CRK26922.1 - 0.0097 15.8 1.5 0.56 10.1 0.0 3.1 3 1 1 4 4 4 1 Phosphotransferase enzyme family SWIRM-assoc_2 PF16496.5 CRK26922.1 - 7.8 5.2 10.6 0.4 9.5 2.7 2.1 2 0 0 2 2 2 0 SWIRM-associated domain at the N-terminal Ribosomal_60s PF00428.19 CRK26923.1 - 3.5e-28 98.0 10.4 4.1e-28 97.8 10.4 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein UBA_6 PF18039.1 CRK26923.1 - 0.065 13.2 1.3 0.074 13.0 0.2 1.6 2 0 0 2 2 2 0 UBA-like domain SPT2 PF08243.11 CRK26924.1 - 3.1e-08 34.1 35.1 3.5e-06 27.5 35.1 2.4 1 1 0 1 1 1 1 SPT2 chromatin protein NUFIP1 PF10453.9 CRK26925.1 - 7.8e-06 25.6 0.3 2.6e-05 24.0 0.0 2.0 2 0 0 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) CENP-K PF11802.8 CRK26925.1 - 0.014 15.0 2.0 0.014 15.0 2.0 1.7 2 0 0 2 2 2 0 Centromere-associated protein K zf_CCCH_4 PF18345.1 CRK26925.1 - 0.038 14.1 6.8 0.072 13.2 6.8 1.5 1 0 0 1 1 1 0 Zinc finger domain MCM3AP_GANP PF16769.5 CRK26925.1 - 0.18 10.0 4.0 0.27 9.4 4.0 1.1 1 0 0 1 1 1 0 MCM3AP domain of GANP zf-CCCH PF00642.24 CRK26925.1 - 0.21 11.6 5.9 0.45 10.5 5.9 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) KOG2701 PF09762.9 CRK26925.1 - 0.26 11.5 1.8 0.61 10.3 1.8 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein (DUF2037) AAA_23 PF13476.6 CRK26925.1 - 0.37 11.3 6.4 0.038 14.5 2.2 1.4 2 0 0 2 2 2 0 AAA domain Atg14 PF10186.9 CRK26925.1 - 8.4 5.4 7.6 14 4.7 7.6 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 RNA_pol_Rbc25 PF08292.12 CRK26926.1 - 8.5e-33 113.3 2.7 1.3e-31 109.5 2.7 2.1 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 CRK26926.1 - 2.3e-13 50.3 0.0 3.9e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 CRK26926.1 - 0.088 13.2 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 S1 RNA binding domain EMC3_TMCO1 PF01956.16 CRK26927.1 - 3.9e-53 179.7 1.7 5e-53 179.3 1.7 1.1 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like SPC25 PF06703.11 CRK26928.1 - 9.8e-45 152.2 0.8 5.9e-44 149.7 0.8 1.9 1 1 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) MMS19_N PF14500.6 CRK26929.1 - 1e-52 179.3 0.0 3.3e-52 177.7 0.0 1.9 1 0 0 1 1 1 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.8 CRK26929.1 - 1.2e-07 31.3 0.0 1.1e-05 24.8 0.0 2.9 3 1 0 3 3 3 2 RNAPII transcription regulator C-terminal LPP PF04728.13 CRK26930.1 - 0.58 10.6 3.5 10 6.6 0.2 2.8 2 0 0 2 2 2 0 Lipoprotein leucine-zipper ATP_bind_1 PF03029.17 CRK26932.1 - 6.3e-72 242.2 0.0 8.3e-72 241.8 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 CRK26932.1 - 0.00025 20.9 0.0 0.00088 19.1 0.0 1.8 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_14 PF13173.6 CRK26932.1 - 0.00058 19.9 0.0 0.002 18.2 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_24 PF13479.6 CRK26932.1 - 0.00083 19.1 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 CRK26932.1 - 0.0032 17.5 0.0 0.0036 17.4 0.0 1.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain RNA_helicase PF00910.22 CRK26932.1 - 0.0046 17.3 0.0 0.011 16.1 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.6 CRK26932.1 - 0.01 16.4 0.0 0.031 14.8 0.0 1.9 2 1 0 2 2 1 0 AAA domain AAA_16 PF13191.6 CRK26932.1 - 0.012 16.0 0.0 0.63 10.4 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain AAA_33 PF13671.6 CRK26932.1 - 0.013 15.7 0.0 0.02 15.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 CRK26932.1 - 0.015 14.8 0.0 2 7.9 0.0 2.7 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Septin PF00735.18 CRK26932.1 - 0.016 14.5 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 Septin RsgA_GTPase PF03193.16 CRK26932.1 - 0.019 14.9 0.3 0.45 10.4 0.1 2.3 2 0 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 CRK26932.1 - 0.02 15.2 0.0 0.044 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 CRK26932.1 - 0.024 13.9 0.0 0.036 13.3 0.0 1.4 1 1 0 1 1 1 0 KAP family P-loop domain MMR_HSR1 PF01926.23 CRK26932.1 - 0.033 14.3 0.0 0.11 12.5 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_7 PF12775.7 CRK26932.1 - 0.052 13.1 0.0 0.082 12.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region PduV-EutP PF10662.9 CRK26932.1 - 0.056 13.2 0.0 1.2 8.8 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 CRK26932.1 - 0.067 13.7 0.0 0.16 12.5 0.0 1.6 1 0 0 1 1 1 0 ABC transporter cobW PF02492.19 CRK26932.1 - 0.089 12.4 0.0 4.9 6.7 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 CRK26932.1 - 0.096 12.6 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NACHT PF05729.12 CRK26932.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Cytidylate_kin PF02224.18 CRK26932.1 - 0.12 12.1 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase SRP54 PF00448.22 CRK26932.1 - 0.12 12.0 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_29 PF13555.6 CRK26932.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain PPV_E1_C PF00519.17 CRK26932.1 - 0.17 10.7 0.0 0.26 10.1 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase FtsK_SpoIIIE PF01580.18 CRK26932.1 - 0.23 10.8 0.4 0.53 9.6 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family S-AdoMet_synt_C PF02773.16 CRK26933.1 - 9.2e-67 223.3 0.3 2e-66 222.2 0.0 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 CRK26933.1 - 2.7e-44 150.3 0.0 5e-44 149.4 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 CRK26933.1 - 2.9e-44 149.8 0.6 8.7e-44 148.2 0.1 2.0 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain Spt20 PF12090.8 CRK26934.1 - 3.5 7.2 12.4 5.3 6.6 12.4 1.2 1 0 0 1 1 1 0 Spt20 family PAT1 PF09770.9 CRK26934.1 - 7.3 4.7 10.8 9.2 4.4 10.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PI-PLC-X PF00388.19 CRK26935.1 - 9.1e-10 38.3 0.0 1.4e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Regulator_TrmB PF11495.8 CRK26935.1 - 9.1e-06 25.0 0.1 0.14 11.4 0.0 2.2 2 0 0 2 2 2 2 Archaeal transcriptional regulator TrmB bPH_6 PF10756.9 CRK26935.1 - 0.0067 16.5 0.0 7 6.8 0.0 2.6 2 0 0 2 2 2 2 Bacterial PH domain His_biosynth PF00977.21 CRK26935.1 - 0.081 12.4 0.0 0.2 11.1 0.0 1.6 2 0 0 2 2 2 0 Histidine biosynthesis protein Spiralin PF05215.13 CRK26935.1 - 0.09 12.1 0.6 5.5 6.3 0.1 2.2 2 0 0 2 2 2 0 Spiralin Ank_2 PF12796.7 CRK26938.1 - 1.6e-38 131.2 3.3 2.5e-13 50.4 0.0 9.3 7 1 1 8 8 8 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CRK26938.1 - 2.1e-33 114.3 3.7 6.3e-06 26.6 0.0 10.5 8 2 2 10 10 10 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 CRK26938.1 - 2.9e-27 94.3 5.1 3.8e-05 23.9 0.2 10.3 9 1 1 10 10 10 6 Ankyrin repeats (many copies) Ank PF00023.30 CRK26938.1 - 3.5e-25 87.3 10.2 0.0032 17.8 0.0 11.2 13 0 0 13 13 13 6 Ankyrin repeat Ank_3 PF13606.6 CRK26938.1 - 1.6e-24 83.3 3.4 0.0063 16.9 0.0 12.7 14 0 0 14 14 14 5 Ankyrin repeat Rad60-SLD PF11976.8 CRK26939.1 - 3.3e-20 71.7 0.0 6.7e-20 70.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 CRK26939.1 - 1.6e-06 27.8 0.0 6.8e-05 22.5 0.0 2.4 2 0 0 2 2 2 1 Ubiquitin family TmoB PF06234.12 CRK26939.1 - 0.00061 19.8 0.1 0.0059 16.7 0.1 2.3 2 0 0 2 2 2 1 Toluene-4-monooxygenase system protein B (TmoB) PGA2 PF07543.12 CRK26939.1 - 2.8 7.9 23.2 3 7.8 3.1 3.4 3 0 0 3 3 3 0 Protein trafficking PGA2 LSM PF01423.22 CRK26940.1 - 9.9e-21 73.2 0.1 1.2e-20 73.0 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CRK26940.1 - 0.00037 20.6 0.1 0.00054 20.1 0.1 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 CRK26940.1 - 0.00053 20.0 0.2 0.00071 19.6 0.2 1.2 1 0 0 1 1 1 1 Scd6-like Sm domain EGF_MSP1_1 PF12946.7 CRK26940.1 - 0.17 12.0 0.0 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 MSP1 EGF domain 1 Methyltransf_25 PF13649.6 CRK26941.1 - 2.3e-16 60.3 0.2 1.2e-09 38.7 0.0 2.7 3 0 0 3 3 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 CRK26941.1 - 5.4e-16 59.0 0.1 4.2e-11 43.4 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 CRK26941.1 - 3.5e-15 56.2 0.0 3.9e-06 26.8 0.0 2.6 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 CRK26941.1 - 7.6e-09 36.2 0.0 0.004 17.9 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 CRK26941.1 - 3.5e-08 33.4 0.0 0.0011 18.8 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.18 CRK26941.1 - 1.1e-07 31.4 0.0 0.0002 20.8 0.0 2.3 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family PCMT PF01135.19 CRK26941.1 - 8.6e-06 25.7 0.0 0.078 12.7 0.0 2.3 2 0 0 2 2 2 2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 CRK26941.1 - 7.6e-05 22.8 0.0 0.44 10.5 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain FtsJ PF01728.19 CRK26941.1 - 0.00011 22.3 0.0 0.61 10.2 0.0 2.3 2 0 0 2 2 2 2 FtsJ-like methyltransferase MTS PF05175.14 CRK26941.1 - 0.00061 19.4 0.8 0.98 9.0 0.1 2.3 2 0 0 2 2 2 2 Methyltransferase small domain MetW PF07021.12 CRK26941.1 - 0.015 14.9 0.5 2.9 7.5 0.1 2.2 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW DREV PF05219.12 CRK26941.1 - 0.033 13.3 0.0 3 6.8 0.0 2.2 2 0 0 2 2 2 0 DREV methyltransferase F-box PF00646.33 CRK26942.1 - 3.5e-06 26.8 0.1 5.8e-06 26.1 0.1 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 CRK26942.1 - 2.9e-05 23.9 0.5 4.9e-05 23.1 0.5 1.5 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 CRK26942.1 - 0.012 15.5 0.0 0.015 15.2 0.0 1.1 1 0 0 1 1 1 0 F-box Pkinase PF00069.25 CRK26943.1 - 3.1e-53 180.8 0.0 7e-53 179.7 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK26943.1 - 6.5e-23 81.3 0.0 1.4e-22 80.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 CRK26943.1 - 2.5e-09 37.3 0.3 2.3e-08 34.3 0.2 2.3 2 0 0 2 2 2 1 FHA domain PH PF00169.29 CRK26943.1 - 1.1e-06 29.1 0.4 1.1e-05 25.8 0.0 2.6 3 0 0 3 3 3 1 PH domain Kdo PF06293.14 CRK26943.1 - 0.0072 15.7 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PH_9 PF15410.6 CRK26943.1 - 0.029 14.7 0.1 0.082 13.3 0.0 1.8 2 0 0 2 2 2 0 Pleckstrin homology domain Yop-YscD_cpl PF16697.5 CRK26943.1 - 0.03 14.6 0.0 0.082 13.2 0.0 1.7 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain Fcf1 PF04900.12 CRK26944.1 - 3.3e-27 94.8 0.1 7.5e-27 93.6 0.1 1.6 1 0 0 1 1 1 1 Fcf1 PP2C_2 PF13672.6 CRK26944.1 - 0.00078 19.1 0.0 0.0014 18.3 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 CRK26944.1 - 0.0048 16.8 0.0 0.014 15.3 0.0 1.8 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 CRK26944.1 - 0.06 13.0 0.7 1.4 8.5 0.0 2.5 3 0 0 3 3 3 0 Protein phosphatase 2C CDC45 PF02724.14 CRK26944.1 - 1.6 6.9 9.1 2.3 6.4 9.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF726 PF05277.12 CRK26945.1 - 2.1e-122 408.4 1.5 2.8e-122 407.9 1.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) SUIM_assoc PF16619.5 CRK26946.1 - 0.01 15.9 6.3 0.01 15.9 6.3 3.1 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Mid2 PF04478.12 CRK26946.1 - 0.031 14.1 0.0 0.11 12.4 0.0 1.9 1 1 0 1 1 1 0 Mid2 like cell wall stress sensor PTR2 PF00854.21 CRK26946.1 - 0.16 10.8 0.0 0.23 10.2 0.0 1.1 1 0 0 1 1 1 0 POT family Shisa PF13908.6 CRK26946.1 - 0.2 11.9 0.0 0.2 11.9 0.0 2.9 2 1 1 3 3 3 0 Wnt and FGF inhibitory regulator DUF846 PF05832.12 CRK26947.1 - 7e-52 175.2 9.3 8.4e-52 174.9 9.3 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) TctB PF07331.11 CRK26947.1 - 2 8.7 13.9 3.5 7.9 4.6 2.2 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family DUF4870 PF09685.10 CRK26947.1 - 3.5 7.8 12.6 0.78 9.9 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4870) EURL PF06937.11 CRK26948.1 - 0.69 9.3 3.3 1 8.7 3.3 1.2 1 0 0 1 1 1 0 EURL protein ORC6 PF05460.13 CRK26948.1 - 2.5 7.3 7.8 5.5 6.1 7.8 1.5 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Macoilin PF09726.9 CRK26948.1 - 4 5.9 9.2 5.8 5.4 9.2 1.1 1 0 0 1 1 1 0 Macoilin family DUF846 PF05832.12 CRK26949.1 - 7e-52 175.2 9.3 8.4e-52 174.9 9.3 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) TctB PF07331.11 CRK26949.1 - 2 8.7 13.9 3.5 7.9 4.6 2.2 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family DUF4870 PF09685.10 CRK26949.1 - 3.5 7.8 12.6 0.78 9.9 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4870) HpcH_HpaI PF03328.14 CRK26950.1 - 3.5e-40 137.5 0.0 6.4e-40 136.6 0.0 1.4 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 CRK26950.1 - 8.4e-12 44.9 0.0 2.2e-07 30.4 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold AAA_18 PF13238.6 CRK26951.1 - 2.9e-08 34.3 0.0 3.9e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CRK26951.1 - 5.1e-05 23.5 0.1 7e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CRK26951.1 - 0.033 14.6 0.0 0.059 13.8 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain KTI12 PF08433.10 CRK26951.1 - 0.074 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 APS_kinase PF01583.20 CRK26951.1 - 0.088 12.7 0.0 0.17 11.8 0.0 1.8 1 1 0 1 1 1 0 Adenylylsulphate kinase HpcH_HpaI PF03328.14 CRK26952.1 - 5.8e-41 140.0 0.0 1.1e-40 139.2 0.0 1.4 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 CRK26952.1 - 5.5e-12 45.5 0.0 1e-07 31.5 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold CSN5_C PF18323.1 CRK26953.1 - 0.28 12.1 1.5 0.92 10.5 0.1 2.6 2 0 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain AAA_18 PF13238.6 CRK26954.1 - 1.4e-08 35.4 0.0 1.8e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CRK26954.1 - 6.9e-05 23.0 0.0 9.6e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 CRK26954.1 - 0.041 13.3 0.0 0.066 12.6 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_16 PF13191.6 CRK26954.1 - 0.08 13.3 0.0 0.13 12.6 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain APS_kinase PF01583.20 CRK26954.1 - 0.083 12.8 0.0 0.15 11.9 0.0 1.7 1 1 0 1 1 1 0 Adenylylsulphate kinase RRM_1 PF00076.22 CRK26955.1 - 2.9e-23 81.5 0.0 3.8e-23 81.1 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CRK26955.1 - 0.00056 20.0 0.0 0.00096 19.2 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif RRM_3 PF08777.11 CRK26955.1 - 0.031 14.3 0.1 0.046 13.8 0.1 1.2 1 0 0 1 1 1 0 RNA binding motif PAP_PilO PF06864.12 CRK26955.1 - 0.12 11.2 0.1 0.15 10.9 0.1 1.1 1 0 0 1 1 1 0 Pilin accessory protein (PilO) ChaC PF04752.12 CRK26956.1 - 1.3e-28 100.3 0.0 1.6e-28 99.9 0.0 1.2 1 0 0 1 1 1 1 ChaC-like protein ChaC PF04752.12 CRK26958.1 - 4.4e-37 127.9 0.0 8.3e-37 127.0 0.0 1.4 1 1 0 1 1 1 1 ChaC-like protein ChaC PF04752.12 CRK26959.1 - 5.6e-23 81.9 0.0 1.2e-22 80.9 0.0 1.4 1 1 0 1 1 1 1 ChaC-like protein DUF3405 PF11885.8 CRK26960.1 - 1.1e-138 463.1 0.2 1.4e-138 462.7 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) DUF1965 PF09248.10 CRK26960.1 - 0.082 12.7 0.4 1.8 8.4 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1965) EF-hand_1 PF00036.32 CRK26961.1 - 2.1e-23 80.1 6.9 1.2e-05 24.5 0.1 5.4 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 CRK26961.1 - 1.5e-21 76.6 3.2 1.2e-09 38.5 0.0 3.8 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 CRK26961.1 - 7.6e-20 69.1 6.0 0.00043 20.0 0.1 5.5 5 0 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 CRK26961.1 - 6.4e-17 61.1 7.7 1.4e-08 34.4 0.0 4.9 3 2 2 5 5 5 4 EF-hand domain pair EF-hand_5 PF13202.6 CRK26961.1 - 9.7e-15 53.3 3.4 0.00036 19.9 0.3 4.4 4 0 0 4 4 4 4 EF hand 2TM PF13239.6 CRK26961.1 - 0.055 13.8 0.8 0.12 12.7 0.8 1.5 1 0 0 1 1 1 0 2TM domain SPX PF03105.19 CRK26961.1 - 1.8 8.4 10.8 5.4 6.8 6.7 2.0 2 0 0 2 2 2 0 SPX domain RdRP PF05183.12 CRK26962.1 - 5.6e-128 428.1 0.0 7.5e-128 427.7 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase EF-hand_1 PF00036.32 CRK26963.1 - 1.9e-25 86.5 6.7 4.7e-06 25.8 0.1 5.3 5 0 0 5 5 5 5 EF hand EF-hand_7 PF13499.6 CRK26963.1 - 5.5e-23 81.2 3.4 3.8e-10 40.1 0.0 3.9 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 CRK26963.1 - 9.1e-22 75.1 6.0 0.00016 21.3 0.1 5.3 5 0 0 5 5 5 5 EF-hand domain EF-hand_8 PF13833.6 CRK26963.1 - 1.1e-18 66.8 8.0 4.9e-09 35.9 0.0 5.0 3 2 2 5 5 5 4 EF-hand domain pair EF-hand_5 PF13202.6 CRK26963.1 - 2.5e-16 58.3 3.4 0.00014 21.2 0.3 4.5 4 0 0 4 4 4 4 EF hand SPX PF03105.19 CRK26963.1 - 0.098 12.6 4.8 0.12 12.3 4.8 1.1 1 0 0 1 1 1 0 SPX domain RdRP PF05183.12 CRK26964.1 - 6.4e-126 421.4 0.0 8.4e-126 421.0 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Hep_59 PF07052.11 CRK26966.1 - 1.7e-17 64.1 1.4 5.1e-15 56.1 0.0 3.5 3 1 0 3 3 3 2 Hepatocellular carcinoma-associated antigen 59 Acylphosphatase PF00708.18 CRK26967.1 - 1.5e-22 79.8 0.6 1.8e-22 79.5 0.6 1.1 1 0 0 1 1 1 1 Acylphosphatase HA2 PF04408.23 CRK26968.1 - 8.7e-44 148.2 7.2 4.3e-21 75.2 0.0 3.7 5 0 0 5 5 4 2 Helicase associated domain (HA2) Helicase_C PF00271.31 CRK26968.1 - 2.1e-25 89.2 0.0 1.1e-13 51.5 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 CRK26968.1 - 4.5e-19 68.6 0.0 1.5e-18 66.9 0.0 2.0 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 CRK26968.1 - 2.2e-07 30.8 0.0 4.1e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CRK26968.1 - 8.9e-06 26.0 0.1 2.6e-05 24.5 0.1 1.7 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 CRK26968.1 - 0.00019 20.8 0.0 0.00036 19.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 CRK26968.1 - 0.00038 20.2 0.1 0.0014 18.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 CRK26968.1 - 0.0011 18.7 0.1 0.0025 17.5 0.1 1.6 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_19 PF13245.6 CRK26968.1 - 0.0017 18.7 0.1 0.0038 17.6 0.1 1.5 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 CRK26968.1 - 0.0039 16.3 0.0 0.0082 15.2 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.15 CRK26968.1 - 0.0046 17.0 0.1 0.91 9.5 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ATPase PF06745.13 CRK26968.1 - 0.0054 16.1 0.0 0.013 14.9 0.0 1.5 1 0 0 1 1 1 1 KaiC ABC_tran PF00005.27 CRK26968.1 - 0.013 16.0 0.0 0.063 13.8 0.0 2.2 1 0 0 1 1 1 0 ABC transporter Flavi_DEAD PF07652.14 CRK26968.1 - 0.017 15.1 0.0 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_24 PF13479.6 CRK26968.1 - 0.033 13.9 0.0 0.065 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 CRK26968.1 - 0.056 13.5 0.2 0.27 11.3 0.2 2.1 1 1 0 1 1 1 0 AAA domain GAD PF02938.14 CRK26968.1 - 0.076 13.3 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 GAD domain WD40 PF00400.32 CRK26969.1 - 1.9e-16 60.2 8.1 0.0078 17.0 0.1 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK26969.1 - 3.7e-07 30.3 1.5 0.0022 18.3 0.2 4.1 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CRK26969.1 - 3.4e-06 26.0 3.6 5.1e-05 22.1 0.7 3.1 2 2 1 3 3 3 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 CRK26969.1 - 0.027 13.2 0.1 3.8 6.2 0.0 2.7 2 1 1 3 3 3 0 Nup133 N terminal like Polysacc_deac_2 PF04748.13 CRK26971.1 - 0.0022 17.2 0.0 0.0039 16.4 0.0 1.4 1 0 0 1 1 1 1 Divergent polysaccharide deacetylase DUF2312 PF10073.9 CRK26971.1 - 0.17 11.5 0.2 14 5.4 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) Cys_Met_Meta_PP PF01053.20 CRK26972.1 - 2.6e-14 52.6 0.0 1.1e-07 30.7 0.0 2.8 2 1 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Sugar_tr PF00083.24 CRK26973.1 - 7.6e-81 272.3 21.4 8.7e-81 272.1 21.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK26973.1 - 5.4e-11 42.0 39.3 1.3e-10 40.8 34.4 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 CRK26973.1 - 1.1e-05 24.9 2.3 1.1e-05 24.9 2.3 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Melibiase_2 PF16499.5 CRK26974.1 - 2.7e-59 200.7 9.6 1.1e-57 195.5 9.6 2.2 1 1 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 CRK26974.1 - 1.3e-10 41.2 5.0 3.8e-09 36.5 0.6 2.8 3 0 0 3 3 3 2 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 CRK26974.1 - 7.7e-08 31.7 0.1 1.7e-07 30.6 0.0 1.5 2 0 0 2 2 2 1 Melibiase Helicase_C PF00271.31 CRK26975.1 - 1e-09 38.7 0.0 2.4e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CRK26975.1 - 6.4e-08 32.6 0.0 6.4e-08 32.6 0.0 1.7 2 0 0 2 2 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CRK26975.1 - 3.8e-06 27.2 0.0 9.3e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 CRK26975.1 - 5.8e-05 22.5 0.3 0.00014 21.2 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 CRK26975.1 - 0.0001 22.1 0.4 0.00054 19.7 0.0 2.2 2 1 1 3 3 3 1 AAA domain SRP54 PF00448.22 CRK26975.1 - 0.00044 19.9 0.2 0.0012 18.6 0.2 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_19 PF13245.6 CRK26975.1 - 0.00064 20.1 0.1 0.0014 19.0 0.1 1.5 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 CRK26975.1 - 0.00075 19.5 0.1 0.43 10.6 0.0 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit T2SSE PF00437.20 CRK26975.1 - 0.0014 17.7 0.0 0.0031 16.6 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein ATPase PF06745.13 CRK26975.1 - 0.0017 17.8 0.0 0.0056 16.1 0.0 1.9 1 0 0 1 1 1 1 KaiC Flavi_DEAD PF07652.14 CRK26975.1 - 0.0059 16.6 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain ABC_tran PF00005.27 CRK26975.1 - 0.0082 16.7 0.9 0.025 15.1 0.0 2.3 3 0 0 3 3 3 1 ABC transporter AAA_24 PF13479.6 CRK26975.1 - 0.011 15.5 0.0 0.026 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 CRK26975.1 - 0.013 15.6 0.2 0.069 13.2 0.2 2.1 1 1 0 1 1 1 0 AAA domain GAD PF02938.14 CRK26975.1 - 0.022 15.0 0.0 0.084 13.1 0.0 2.0 2 0 0 2 2 2 0 GAD domain AAA_16 PF13191.6 CRK26975.1 - 0.057 13.8 1.6 0.4 11.0 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain AAA_23 PF13476.6 CRK26975.1 - 0.081 13.4 0.3 1.1 9.7 0.0 2.6 3 0 0 3 3 3 0 AAA domain Myosin_head PF00063.21 CRK26975.1 - 0.091 11.0 0.0 0.17 10.1 0.0 1.4 1 0 0 1 1 1 0 Myosin head (motor domain) AAA_7 PF12775.7 CRK26975.1 - 0.13 11.8 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region WD40 PF00400.32 CRK26976.1 - 1.8e-16 60.2 6.5 0.012 16.4 0.1 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK26976.1 - 5.6e-07 29.8 1.7 0.0031 17.8 0.2 3.9 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CRK26976.1 - 8.8e-06 24.6 3.2 9.2e-05 21.3 0.8 3.0 2 2 1 3 3 3 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 CRK26976.1 - 0.021 13.6 0.0 5.4 5.6 0.0 2.8 2 1 1 3 3 3 0 Nup133 N terminal like BRF1 PF07741.13 CRK26977.1 - 5.9 7.3 0.0 5.9 7.3 0.0 2.8 3 1 0 3 3 3 0 Brf1-like TBP-binding domain Polysacc_deac_1 PF01522.21 CRK26978.1 - 1.7e-22 79.6 0.0 4.1e-22 78.4 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide deacetylase Terpene_synth_C PF03936.16 CRK26978.1 - 0.0026 17.2 0.2 0.006 16.0 0.2 1.6 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain Polysacc_deac_2 PF04748.13 CRK26978.1 - 0.026 13.7 0.0 0.074 12.2 0.0 1.7 2 0 0 2 2 2 0 Divergent polysaccharide deacetylase Sugar_tr PF00083.24 CRK26981.1 - 6.2e-81 272.6 20.1 7.1e-81 272.4 20.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK26981.1 - 6.7e-11 41.7 33.8 6.7e-11 41.7 33.8 2.5 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 CRK26981.1 - 4.9e-06 26.1 2.1 4.9e-06 26.1 2.1 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Phage_holin_2_4 PF16082.5 CRK26981.1 - 4.7 7.0 5.6 2.1 8.1 0.1 3.0 3 0 0 3 3 3 0 Bacteriophage holin family, superfamily II-like Melibiase_2 PF16499.5 CRK26982.1 - 3.5e-60 203.6 9.3 1.4e-58 198.4 9.3 2.2 1 1 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 CRK26982.1 - 2e-11 43.8 3.2 1.8e-09 37.5 0.5 2.8 3 0 0 3 3 3 2 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 CRK26982.1 - 5e-08 32.3 0.1 1.3e-07 30.9 0.0 1.6 2 0 0 2 2 2 1 Melibiase COesterase PF00135.28 CRK26983.1 - 1.5e-77 261.6 0.0 1.8e-77 261.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CRK26983.1 - 5e-09 36.3 1.2 2.3e-06 27.6 0.2 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF4265 PF14085.6 CRK26983.1 - 0.2 11.6 0.0 0.97 9.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4265) HEPN_Swt1 PF18731.1 CRK26984.1 - 0.02 15.2 0.0 0.04 14.3 0.0 1.5 1 0 0 1 1 1 0 Swt1-like HEPN His_Phos_2 PF00328.22 CRK26984.1 - 0.051 12.9 0.0 0.067 12.5 0.0 1.2 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) STT3 PF02516.14 CRK26985.1 - 5.4e-138 461.0 34.2 9.7e-134 446.9 32.0 2.2 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit ATP-synt_E PF05680.12 CRK26985.1 - 3.7e-21 75.3 0.2 1.4e-20 73.4 0.2 2.0 1 0 0 1 1 1 1 ATP synthase E chain Dpy19 PF10034.9 CRK26985.1 - 0.035 12.3 1.0 0.057 11.6 1.0 1.3 1 0 0 1 1 1 0 Q-cell neuroblast polarisation DUF5490 PF17593.2 CRK26985.1 - 0.18 11.8 1.1 1.5 8.9 0.2 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5490) DUF2752 PF10825.8 CRK26985.1 - 6.9 6.8 11.9 2.1 8.5 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2752) WD40 PF00400.32 CRK26986.1 - 1.4e-07 32.1 12.5 0.036 14.9 1.3 5.8 6 1 0 6 6 6 3 WD domain, G-beta repeat Aldo_ket_red PF00248.21 CRK26987.1 - 2.7e-60 204.1 0.0 3.1e-60 203.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MaoC_dehydratas PF01575.19 CRK26988.1 - 1.2e-20 73.3 0.0 2.2e-20 72.5 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain CAP_GLY PF01302.25 CRK26988.1 - 2.1e-18 66.1 0.1 3.7e-18 65.3 0.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.7 CRK26988.1 - 8.3e-11 41.9 4.0 0.0059 17.0 0.0 5.2 5 1 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CRK26988.1 - 2.4e-09 36.8 3.4 0.0022 17.7 0.6 4.4 4 1 0 4 4 4 3 Leucine rich repeat LRR_9 PF14580.6 CRK26988.1 - 3.6e-07 29.9 0.0 0.00013 21.5 0.0 2.9 4 0 0 4 4 4 2 Leucine-rich repeat LRR_6 PF13516.6 CRK26988.1 - 6.5e-05 22.7 0.8 30 5.0 0.0 6.3 6 0 0 6 6 6 0 Leucine Rich repeat MaoC_dehydrat_N PF13452.6 CRK26988.1 - 0.00017 21.7 0.0 0.0063 16.7 0.0 2.5 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase Torus PF16131.5 CRK26988.1 - 0.013 16.2 3.2 0.028 15.1 3.2 1.4 1 0 0 1 1 1 0 Torus domain zf-CCCH_4 PF18044.1 CRK26988.1 - 1.4 8.8 14.9 2.7 7.9 14.9 1.4 1 0 0 1 1 1 0 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CRK26988.1 - 6.5 7.0 15.0 11 6.2 15.0 1.4 1 0 0 1 1 1 0 Zinc finger domain Pkinase PF00069.25 CRK26991.1 - 3.8e-90 301.8 0.1 4.7e-37 127.8 0.0 4.4 4 0 0 4 4 4 4 Protein kinase domain Sugar_tr PF00083.24 CRK26991.1 - 3.3e-41 141.6 51.7 2.6e-13 49.6 5.1 4.3 3 1 1 4 4 4 4 Sugar (and other) transporter Pkinase_Tyr PF07714.17 CRK26991.1 - 5.6e-41 140.5 0.2 4.7e-19 68.7 0.0 4.3 4 0 0 4 4 4 4 Protein tyrosine kinase Response_reg PF00072.24 CRK26991.1 - 1.7e-30 105.5 0.1 9.2e-14 51.6 0.0 2.5 2 0 0 2 2 2 2 Response regulator receiver domain CVNH PF08881.10 CRK26991.1 - 1.1e-26 93.5 11.0 8.3e-13 48.9 1.8 3.1 3 0 0 3 3 2 2 CVNH domain Kinase-like PF14531.6 CRK26991.1 - 3.8e-13 49.4 0.0 0.0016 17.8 0.0 4.3 4 0 0 4 4 4 2 Kinase-like HLH PF00010.26 CRK26991.1 - 3e-11 43.1 0.2 9.4e-11 41.5 0.2 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Aldedh PF00171.22 CRK26991.1 - 3e-07 29.3 0.1 3e-07 29.3 0.1 1.6 2 0 0 2 2 2 1 Aldehyde dehydrogenase family APH PF01636.23 CRK26991.1 - 1.4e-06 28.4 3.6 0.088 12.7 0.1 4.2 3 1 0 4 4 4 2 Phosphotransferase enzyme family PhoD PF09423.10 CRK26991.1 - 1.7e-05 24.0 9.1 0.0045 16.0 0.1 3.9 6 0 0 6 6 6 2 PhoD-like phosphatase Seadorna_VP7 PF07387.11 CRK26991.1 - 2.8e-05 23.3 0.0 0.18 10.8 0.0 2.2 2 0 0 2 2 2 2 Seadornavirus VP7 Kdo PF06293.14 CRK26991.1 - 0.0001 21.7 0.1 0.48 9.7 0.0 2.5 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CRK26991.1 - 0.002 17.1 10.3 0.074 12.0 0.1 2.7 3 0 0 3 3 2 2 Haspin like kinase domain FIST_C PF10442.9 CRK26991.1 - 0.0063 16.5 0.0 6 6.9 0.0 2.6 2 0 0 2 2 2 2 FIST C domain PAS_9 PF13426.7 CRK26991.1 - 0.017 15.4 0.0 0.054 13.7 0.0 1.9 1 0 0 1 1 1 0 PAS domain GP17 PF17420.2 CRK26991.1 - 0.34 11.1 1.5 31 4.8 0.1 2.5 2 0 0 2 2 2 0 Superinfection exclusion gene product 17 Acyltransf_C PF16076.5 CRK26992.1 - 2.7e-11 43.4 0.3 8.2e-11 41.8 0.3 1.7 1 0 0 1 1 1 1 Acyltransferase C-terminus Acyltransferase PF01553.21 CRK26992.1 - 0.00011 21.8 0.0 0.00016 21.3 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase LAL_C2 PF18603.1 CRK26992.1 - 0.12 12.6 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 L-amino acid ligase C-terminal domain 2 eIF-3_zeta PF05091.12 CRK26993.1 - 6.1e-94 315.9 0.2 8.6e-80 269.2 0.1 2.6 2 0 0 2 2 2 2 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) MDM31_MDM32 PF08118.11 CRK26993.1 - 2.1e-72 244.5 0.2 3.4e-72 243.8 0.2 1.2 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins bZIP_1 PF00170.21 CRK26993.1 - 1.4e-08 34.7 21.8 0.00054 20.0 6.9 2.4 2 0 0 2 2 2 2 bZIP transcription factor Glyphos_transf PF04464.14 CRK26993.1 - 0.0028 16.7 0.0 2.2 7.2 0.0 2.2 2 0 0 2 2 2 2 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase Rsbr_N PF08678.10 CRK26993.1 - 0.035 14.2 1.0 13 5.8 0.1 2.7 3 0 0 3 3 3 0 Rsbr N terminal DUF569 PF04601.13 CRK26993.1 - 0.041 13.6 0.0 0.12 12.1 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF569) YabA PF06156.13 CRK26993.1 - 0.13 12.9 1.2 26 5.5 0.1 2.6 2 0 0 2 2 2 0 Initiation control protein YabA bZIP_2 PF07716.15 CRK26993.1 - 0.55 10.4 19.7 1.6 8.9 4.4 3.0 2 2 0 2 2 2 0 Basic region leucine zipper AceK PF06315.11 CRK26993.1 - 0.73 8.2 6.4 5.1 5.5 0.6 2.2 2 0 0 2 2 2 0 Isocitrate dehydrogenase kinase/phosphatase (AceK) RBR PF17208.3 CRK26993.1 - 1.1 10.0 15.6 2.8 8.7 1.6 3.6 3 0 0 3 3 3 0 RNA binding Region DUF5082 PF16888.5 CRK26993.1 - 1.4 9.2 9.5 8.2 6.7 1.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) DUF4559 PF15112.6 CRK26993.1 - 3.9 7.1 6.7 18 4.8 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4559) CALCOCO1 PF07888.11 CRK26993.1 - 5.8 5.7 12.1 7.5 5.3 2.4 2.2 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like KH_8 PF17903.1 CRK26994.1 - 0.00017 21.6 0.0 0.00035 20.6 0.0 1.4 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 CRK26994.1 - 0.073 12.9 0.3 0.16 11.9 0.3 1.6 1 0 0 1 1 1 0 KH domain MDM31_MDM32 PF08118.11 CRK26995.1 - 2.3e-104 350.0 0.0 2.5e-104 349.8 0.0 1.0 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins eIF3_subunit PF08597.10 CRK26996.1 - 1.2e-67 228.4 24.8 1.4e-67 228.2 24.8 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit LMBR1 PF04791.16 CRK26996.1 - 0.41 9.5 2.6 0.56 9.1 2.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein AOX PF01786.17 CRK26997.1 - 4.5e-90 300.9 0.0 5.1e-90 300.8 0.0 1.0 1 0 0 1 1 1 1 Alternative oxidase Trypan_PARP PF05887.11 CRK26999.1 - 0.00033 20.6 21.0 0.00033 20.6 21.0 17.4 8 4 7 15 15 15 3 Procyclic acidic repetitive protein (PARP) CFEM PF05730.11 CRK27000.1 - 1.5e-14 53.8 12.3 1.5e-14 53.8 12.3 1.7 2 0 0 2 2 2 1 CFEM domain Sporozoite_P67 PF05642.11 CRK27000.1 - 0.028 12.5 4.9 0.028 12.5 4.9 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Trypan_PARP PF05887.11 CRK27018.1 - 0.083 12.9 5.7 0.14 12.1 5.7 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) fn3_2 PF16893.5 CRK27020.1 - 8.1e-39 131.7 0.0 1.3e-38 131.0 0.0 1.3 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 CRK27020.1 - 2.5e-19 69.0 1.1 4.9e-19 68.0 1.1 1.4 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus PTCB-BRCT PF12738.7 CRK27020.1 - 1.8e-11 43.8 0.0 3.1e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 CRK27020.1 - 6e-10 39.4 0.0 1e-09 38.7 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 CRK27020.1 - 1.6e-05 25.2 0.0 3e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain fn3 PF00041.21 CRK27020.1 - 0.0016 18.8 0.0 0.0057 17.0 0.0 2.0 1 1 0 1 1 1 1 Fibronectin type III domain KAR9 PF08580.10 CRK27020.1 - 0.2 10.1 1.0 0.28 9.7 1.0 1.3 1 0 0 1 1 1 0 Yeast cortical protein KAR9 FAM176 PF14851.6 CRK27020.1 - 2 8.1 4.4 4.2 7.0 4.4 1.5 1 0 0 1 1 1 0 FAM176 family adh_short PF00106.25 CRK27021.1 - 1.1e-08 34.8 0.0 0.00079 18.9 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CRK27021.1 - 1.4e-05 24.8 0.0 0.00085 18.9 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK27021.1 - 0.00032 20.6 0.0 0.00053 19.9 0.0 1.3 1 0 0 1 1 1 1 KR domain ERCC4 PF02732.15 CRK27023.1 - 3.3e-19 69.6 0.0 5.6e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain DUF2953 PF11167.8 CRK27024.1 - 0.084 13.0 1.2 0.13 12.3 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2953) Ank_4 PF13637.6 CRK27025.1 - 2.8e-31 107.5 2.1 3.8e-11 43.3 0.0 4.1 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 CRK27025.1 - 7.4e-29 100.2 0.5 1.6e-14 54.3 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 CRK27025.1 - 1.1e-25 88.9 10.5 2.6e-07 30.8 0.4 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 CRK27025.1 - 5.5e-24 83.9 12.9 3.4e-09 36.8 0.1 4.4 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 CRK27025.1 - 5.6e-22 75.5 0.7 7.8e-05 22.8 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeat Raptor_N PF14538.6 CRK27029.1 - 2.8e-64 215.5 0.0 4.6e-64 214.8 0.0 1.3 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain DLEU7 PF15760.5 CRK27029.1 - 0.28 10.6 3.4 0.55 9.7 3.4 1.4 1 0 0 1 1 1 0 Leukemia-associated protein 7 Kelch_4 PF13418.6 CRK27030.1 - 8.8e-09 35.2 0.1 0.00023 21.1 0.0 2.5 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_3 PF13415.6 CRK27030.1 - 1.9e-06 28.0 0.2 1.2e-05 25.5 0.1 2.4 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_1 PF01344.25 CRK27030.1 - 3.8e-06 26.4 0.2 0.069 12.7 0.0 2.4 2 0 0 2 2 2 2 Kelch motif Kelch_2 PF07646.15 CRK27030.1 - 3.2e-05 23.7 0.0 0.18 11.9 0.0 2.5 2 0 0 2 2 2 2 Kelch motif Kelch_6 PF13964.6 CRK27030.1 - 7.5e-05 22.9 0.0 0.59 10.5 0.0 2.5 2 0 0 2 2 2 2 Kelch motif Kelch_5 PF13854.6 CRK27030.1 - 0.00014 21.8 0.1 0.23 11.5 0.0 2.4 2 0 0 2 2 2 2 Kelch motif Raptor_N PF14538.6 CRK27031.1 - 1.5e-63 213.1 0.0 3.5e-63 212.0 0.0 1.7 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain ANAPC4_WD40 PF12894.7 CRK27031.1 - 8.9e-10 38.7 0.1 1.6 9.1 0.1 6.1 3 2 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CRK27031.1 - 4.7e-06 27.2 4.0 15 6.7 0.0 6.7 6 0 0 6 6 6 1 WD domain, G-beta repeat BBS2_Mid PF14783.6 CRK27031.1 - 1.6e-05 24.9 0.7 0.49 10.4 0.2 3.7 2 1 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region HEAT_2 PF13646.6 CRK27031.1 - 0.0015 18.9 0.5 0.41 11.1 0.0 3.6 4 0 0 4 4 4 1 HEAT repeats Atx10homo_assoc PF09759.9 CRK27031.1 - 0.0039 17.2 0.1 0.0076 16.3 0.1 1.4 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain Cnd1 PF12717.7 CRK27031.1 - 0.026 14.6 0.0 0.68 10.0 0.0 2.3 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 Hexokinase_1 PF00349.21 CRK27031.1 - 0.036 14.0 0.1 8.4 6.2 0.0 2.3 2 0 0 2 2 2 0 Hexokinase HEAT PF02985.22 CRK27031.1 - 0.098 13.0 7.1 5.9 7.4 0.1 5.3 8 0 0 8 8 8 0 HEAT repeat DLEU7 PF15760.5 CRK27031.1 - 0.4 10.1 3.6 0.89 9.0 3.6 1.5 1 0 0 1 1 1 0 Leukemia-associated protein 7 tRNA-synt_2 PF00152.20 CRK27032.1 - 7.4e-107 357.1 0.0 7.3e-68 228.9 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CRK27032.1 - 5.1e-09 36.0 0.1 0.00052 20.0 0.0 2.4 2 0 0 2 2 2 2 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.6 CRK27032.1 - 0.00013 22.1 0.1 0.86 9.8 0.0 2.4 2 0 0 2 2 2 2 OB-fold nucleic acid binding domain MCM_N PF14551.6 CRK27032.1 - 0.0038 17.8 0.4 4.6 7.9 0.1 2.6 2 0 0 2 2 2 2 MCM N-terminal domain YfkD PF14167.6 CRK27032.1 - 0.013 14.7 0.1 6 6.0 0.0 2.5 2 0 0 2 2 2 0 YfkD-like protein Phage_tail_L PF05100.12 CRK27032.1 - 0.047 13.0 0.0 9.7 5.4 0.0 2.2 2 0 0 2 2 2 0 Phage minor tail protein L LisH_2 PF16045.5 CRK27032.1 - 0.17 10.9 0.1 20 4.3 0.0 2.3 2 0 0 2 2 2 0 LisH Pox_RNA_pol_35 PF03396.15 CRK27032.1 - 0.54 9.5 2.0 5 6.3 0.3 2.2 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase, 35 kD subunit SR-25 PF10500.9 CRK27032.1 - 3 7.4 14.9 2.9 7.5 2.9 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein NARP1 PF12569.8 CRK27032.1 - 3.1 6.6 20.7 1.8 7.4 6.3 2.1 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 SAE2 PF08573.10 CRK27032.1 - 4.3 8.5 6.9 1.7 9.8 0.7 2.7 2 0 0 2 2 2 0 DNA repair protein endonuclease SAE2/CtIP C-terminus DUF1752 PF08550.10 CRK27033.1 - 4.9e-13 48.7 0.5 8.8e-13 47.8 0.5 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Pkinase PF00069.25 CRK27035.1 - 4.5e-60 203.2 0.0 3e-59 200.5 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK27035.1 - 7e-28 97.6 0.6 1.8e-19 70.1 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CRK27035.1 - 0.0027 17.7 0.3 0.17 11.8 0.1 3.2 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase_C PF00433.24 CRK27035.1 - 0.0066 17.1 1.1 0.027 15.2 1.1 2.1 1 1 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 CRK27035.1 - 0.012 14.9 0.0 0.038 13.3 0.0 1.7 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 CRK27035.1 - 0.051 12.9 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CRK27035.1 - 0.062 12.2 0.0 0.093 11.6 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain CFEM PF05730.11 CRK27035.1 - 4.7 7.4 8.1 10 6.3 8.1 1.5 1 0 0 1 1 1 0 CFEM domain Wbp11 PF09429.10 CRK27036.1 - 2.6e-23 82.2 12.6 2.6e-23 82.2 12.6 2.0 2 0 0 2 2 2 1 WW domain binding protein 11 Lipoprotein_7 PF01540.16 CRK27036.1 - 0.056 12.7 3.0 0.079 12.2 3.0 1.1 1 0 0 1 1 1 0 Adhesin lipoprotein Zn_clus PF00172.18 CRK27037.1 - 3e-07 30.4 9.6 5.6e-07 29.6 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CENP-F_leu_zip PF10473.9 CRK27037.1 - 0.043 13.8 0.4 0.091 12.8 0.4 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Acatn PF13000.7 CRK27038.1 - 1.5e-141 472.7 20.9 1.2e-62 212.2 10.7 3.3 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 CENP-O PF09496.10 CRK27039.1 - 1.5e-67 227.7 0.4 3.4e-67 226.5 0.0 1.6 2 0 0 2 2 2 1 Cenp-O kinetochore centromere component DNA_pol_A_exoN PF18305.1 CRK27039.1 - 0.017 15.4 0.1 0.047 14.0 0.1 1.7 1 0 0 1 1 1 0 3' to 5' exonuclease C-terminal domain Phage_GP20 PF06810.11 CRK27039.1 - 0.14 12.0 2.3 0.18 11.6 0.6 1.9 2 0 0 2 2 2 0 Phage minor structural protein GP20 MFS_1 PF07690.16 CRK27040.1 - 7.7e-38 130.3 34.3 1.7e-37 129.2 20.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK27040.1 - 1.3e-08 34.2 5.6 2.5e-08 33.2 5.6 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 CRK27040.1 - 0.0012 17.4 0.7 0.0016 16.9 0.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 CRK27040.1 - 0.0031 16.5 0.0 0.018 13.9 0.0 2.4 2 1 0 2 2 2 1 MFS_1 like family Pyridoxal_deC PF00282.19 CRK27041.1 - 1.3e-59 201.8 0.0 1.8e-59 201.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 CRK27041.1 - 6.9e-05 22.0 0.0 0.00017 20.7 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 CRK27041.1 - 0.18 11.1 0.0 0.32 10.3 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family GRA6 PF05084.13 CRK27042.1 - 0.063 13.2 9.2 0.12 12.3 9.2 1.5 1 0 0 1 1 1 0 Granule antigen protein (GRA6) AMP-binding PF00501.28 CRK27043.1 - 1.1e-76 258.1 0.1 1.4e-76 257.8 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CRK27043.1 - 5.3e-13 49.7 0.5 1.5e-12 48.3 0.5 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 2OG-FeII_Oxy_2 PF13532.6 CRK27044.1 - 4.8e-21 75.8 0.0 8.2e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ATP12 PF07542.11 CRK27045.1 - 7.5e-26 90.7 2.2 8.8e-24 84.0 0.0 2.8 2 1 1 3 3 3 2 ATP12 chaperone protein Htr2 PF17909.1 CRK27046.1 - 0.11 12.8 10.2 1.7 9.0 0.3 3.6 3 0 0 3 3 3 0 Htr2 transmembrane domain TPR_7 PF13176.6 CRK27046.1 - 0.44 10.7 2.3 40 4.6 0.2 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Plus-3 PF03126.18 CRK27047.1 - 9.6e-32 109.8 0.0 3.8e-31 107.8 0.0 2.1 2 0 0 2 2 2 1 Plus-3 domain zf-NOSIP PF15906.5 CRK27047.1 - 0.089 12.9 1.1 23 5.2 0.1 2.8 2 0 0 2 2 2 0 Zinc-finger of nitric oxide synthase-interacting protein Histone_H2A_C PF16211.5 CRK27047.1 - 4.4 7.1 14.0 5.6 6.8 0.0 4.3 4 0 0 4 4 4 0 C-terminus of histone H2A COQ7 PF03232.13 CRK27048.1 - 7.4e-71 237.4 0.1 9e-71 237.2 0.1 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 CRK27048.1 - 0.00084 19.7 0.0 0.0015 18.9 0.0 1.4 1 0 0 1 1 1 1 Rubrerythrin PLDc_2 PF13091.6 CRK27049.1 - 3.9e-08 33.2 0.0 8.9e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 PLD-like domain PLDc PF00614.22 CRK27049.1 - 1.9e-06 27.8 0.0 3.9e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Phospholipase D Active site motif PRK PF00485.18 CRK27052.1 - 0.00015 21.6 1.9 0.0032 17.2 1.9 2.1 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 CRK27052.1 - 0.0068 16.9 1.9 0.025 15.1 0.2 2.3 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 CRK27052.1 - 0.015 14.5 0.0 0.022 13.9 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Zeta_toxin PF06414.12 CRK27052.1 - 0.018 14.4 0.1 0.031 13.6 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin DUF4813 PF16072.5 CRK27052.1 - 0.084 12.5 11.2 0.11 12.1 11.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) AAA_33 PF13671.6 CRK27052.1 - 0.11 12.7 1.5 1.1 9.4 0.1 2.3 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 CRK27052.1 - 0.11 12.2 0.1 0.19 11.4 0.1 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_17 PF13207.6 CRK27052.1 - 0.14 12.6 1.2 2.9 8.3 0.1 2.2 2 0 0 2 2 2 0 AAA domain GFO_IDH_MocA PF01408.22 CRK27054.1 - 2.2e-14 54.3 0.0 4.2e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 CRK27054.1 - 0.01 15.8 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain MFS_1 PF07690.16 CRK27055.1 - 3.2e-31 108.6 52.9 5.2e-30 104.6 52.9 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily ATG22 PF11700.8 CRK27055.1 - 7.7e-05 21.5 1.6 7.7e-05 21.5 1.6 2.9 2 1 1 3 3 3 1 Vacuole effluxer Atg22 like MFS_1_like PF12832.7 CRK27055.1 - 0.00044 19.2 8.8 0.00044 19.2 8.8 2.1 2 0 0 2 2 2 1 MFS_1 like family DUF4969 PF16339.5 CRK27055.1 - 0.085 13.2 0.6 0.19 12.1 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4969) Spore_III_AF PF09581.10 CRK27055.1 - 0.088 12.8 0.1 0.17 11.9 0.1 1.5 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) OATP PF03137.20 CRK27055.1 - 0.53 8.5 15.4 0.23 9.7 3.0 2.7 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DAO PF01266.24 CRK27056.1 - 7.5e-06 25.8 0.0 1e-05 25.3 0.0 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CRK27056.1 - 8.2e-06 26.0 0.1 1.7e-05 24.9 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 CRK27056.1 - 3.5e-05 24.3 0.7 9.4e-05 22.9 0.0 2.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CRK27056.1 - 0.0066 15.7 0.0 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CRK27056.1 - 0.055 13.5 0.0 0.091 12.7 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding GIDA PF01134.22 CRK27056.1 - 0.096 11.7 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 CRK27056.1 - 0.15 12.0 0.0 0.36 10.7 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FSH1 PF03959.13 CRK27057.1 - 3.6e-24 85.6 0.0 8.2e-24 84.4 0.0 1.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) CDH PF02611.15 CRK27057.1 - 0.21 11.2 0.0 0.29 10.7 0.0 1.1 1 0 0 1 1 1 0 CDP-diacylglycerol pyrophosphatase UDPGT PF00201.18 CRK27058.1 - 1.9e-22 79.7 0.0 3.1e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CRK27058.1 - 1.2e-08 35.1 0.0 2.7e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain ketoacyl-synt PF00109.26 CRK27059.1 - 2.7e-79 266.3 0.0 5e-79 265.4 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 CRK27059.1 - 1.7e-60 204.0 0.1 2.1e-59 200.4 0.0 2.4 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 CRK27059.1 - 6e-49 166.9 2.0 9.4e-49 166.2 2.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 CRK27059.1 - 9.1e-47 160.1 0.9 2.1e-46 158.9 0.9 1.6 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 CRK27059.1 - 3.9e-36 123.7 0.0 1.3e-35 121.9 0.0 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.26 CRK27059.1 - 4.8e-20 71.9 0.6 3.3e-18 65.9 0.1 3.7 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CRK27059.1 - 4.7e-19 69.8 0.0 3.6e-17 63.6 0.0 3.5 3 0 0 3 3 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.12 CRK27059.1 - 6.8e-19 68.4 0.0 2.4e-18 66.7 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 CRK27059.1 - 2.3e-13 50.6 0.9 9.5e-12 45.4 0.9 2.9 1 1 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_23 PF13489.6 CRK27059.1 - 4.7e-13 49.3 0.0 1e-12 48.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK27059.1 - 2.2e-11 44.3 0.0 9.9e-11 42.2 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK27059.1 - 9.3e-11 41.7 0.0 2.6e-10 40.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 CRK27059.1 - 3.2e-10 39.8 0.1 4.3e-09 36.1 0.0 2.5 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_11 PF08241.12 CRK27059.1 - 2.1e-08 34.7 0.0 1e-07 32.5 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain PP-binding PF00550.25 CRK27059.1 - 6.4e-08 32.8 0.1 9.5e-07 29.1 0.0 2.6 2 0 0 2 2 2 1 Phosphopantetheine attachment site ADH_N PF08240.12 CRK27059.1 - 1.2e-05 25.2 1.5 3.4e-05 23.7 1.5 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Ubie_methyltran PF01209.18 CRK27059.1 - 9e-05 21.9 0.0 0.0002 20.8 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.23 CRK27059.1 - 0.0042 16.5 0.0 0.012 15.0 0.0 1.7 1 0 0 1 1 1 1 Thiolase, N-terminal domain Sacchrp_dh_NADP PF03435.18 CRK27059.1 - 0.016 15.5 0.3 0.21 11.9 0.0 2.5 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 CRK27059.1 - 0.03 13.5 0.0 0.046 12.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF938 PF06080.12 CRK27059.1 - 0.04 13.7 0.0 0.3 10.8 0.0 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF938) NodS PF05401.11 CRK27059.1 - 0.11 12.0 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Nodulation protein S (NodS) Sulfate_transp PF00916.20 CRK27060.1 - 7.5e-90 301.4 26.0 1.6e-87 293.8 26.0 2.1 1 1 0 1 1 1 1 Sulfate permease family STAS PF01740.21 CRK27060.1 - 7.4e-09 35.3 0.0 1.4e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 STAS domain Lactamase_B PF00753.27 CRK27061.1 - 3.1e-15 56.7 4.4 1.8e-14 54.3 4.4 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CRK27061.1 - 0.0033 16.9 0.5 0.0056 16.2 0.5 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Transposase_21 PF02992.14 CRK27061.1 - 0.089 12.0 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Transposase family tnp2 Cytomega_UL20A PF05984.12 CRK27063.1 - 0.044 14.1 0.3 0.06 13.7 0.3 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL20A protein Rotamase_2 PF13145.6 CRK27064.1 - 0.032 15.1 0.5 0.046 14.6 0.5 1.2 1 0 0 1 1 1 0 PPIC-type PPIASE domain Peptidase_M24 PF00557.24 CRK27065.1 - 3.5e-44 151.0 0.0 4.8e-44 150.5 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 YL1 PF05764.13 CRK27065.1 - 0.015 15.4 5.7 0.024 14.8 5.7 1.3 1 0 0 1 1 1 0 YL1 nuclear protein DUF4604 PF15377.6 CRK27065.1 - 0.028 14.8 9.7 0.047 14.1 9.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) DUF1387 PF07139.11 CRK27065.1 - 0.16 11.7 3.2 0.3 10.8 3.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) CCDC106 PF15794.5 CRK27065.1 - 0.22 11.2 3.5 0.35 10.5 3.5 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 SPT6_acidic PF14632.6 CRK27065.1 - 1.1 9.9 7.4 0.078 13.6 2.1 1.8 2 0 0 2 2 2 0 Acidic N-terminal SPT6 PGA2 PF07543.12 CRK27065.1 - 3 7.8 7.1 8 6.4 7.1 1.6 1 0 0 1 1 1 0 Protein trafficking PGA2 Kinesin_assoc PF16183.5 CRK27066.1 - 0.0063 16.7 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 Kinesin-associated FadA PF09403.10 CRK27066.1 - 0.01 16.3 2.1 0.025 15.1 2.1 1.6 1 0 0 1 1 1 0 Adhesion protein FadA DUF1640 PF07798.11 CRK27066.1 - 0.059 13.4 0.3 0.11 12.5 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Fzo_mitofusin PF04799.13 CRK27066.1 - 0.14 11.7 1.1 0.26 10.8 0.8 1.6 2 0 0 2 2 2 0 fzo-like conserved region Aminotran_4 PF01063.19 CRK27067.1 - 2.9e-21 76.4 0.0 4e-21 75.9 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV DUF2007 PF09413.10 CRK27068.1 - 0.008 16.3 0.0 0.021 15.0 0.0 1.6 2 0 0 2 2 2 1 Putative prokaryotic signal transducing protein CTP_transf_like PF01467.26 CRK27069.1 - 5.3e-26 91.5 0.0 2.3e-22 79.7 0.0 3.3 2 1 0 3 3 3 3 Cytidylyltransferase-like Mito_fiss_reg PF05308.11 CRK27070.1 - 1.5 8.9 4.8 2.6 8.1 4.8 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 CRK27070.1 - 6.3 6.2 6.0 11 5.4 6.0 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal WD40 PF00400.32 CRK27071.1 - 2e-17 63.2 10.3 0.00081 20.2 0.0 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat WD40_like PF17005.5 CRK27071.1 - 6.3e-06 25.7 0.0 1.4e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 WD40-like domain ANAPC4_WD40 PF12894.7 CRK27071.1 - 8.8e-05 22.7 0.0 1.3 9.4 0.0 4.4 1 1 4 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CRK27071.1 - 0.075 11.7 0.1 0.68 8.5 0.1 2.0 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Plectin PF00681.20 CRK27072.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Plectin repeat GHMP_kinases_N PF00288.26 CRK27074.1 - 3.9e-10 39.8 0.0 7.9e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 CRK27074.1 - 0.02 15.2 0.2 0.045 14.1 0.2 1.5 1 0 0 1 1 1 0 GHMP kinases C terminal Cerato-platanin PF07249.12 CRK27075.1 - 1e-50 170.8 0.7 1.4e-50 170.3 0.7 1.2 1 0 0 1 1 1 1 Cerato-platanin NUT PF12881.7 CRK27075.1 - 0.069 11.6 1.7 0.086 11.3 1.7 1.0 1 0 0 1 1 1 0 NUT protein MucB_RseB_C PF17188.4 CRK27075.1 - 0.13 12.5 0.0 2.5 8.4 0.0 2.4 2 1 0 2 2 2 0 MucB/RseB C-terminal domain FXMRP1_C_core PF12235.8 CRK27075.1 - 1.7 9.3 9.3 2.6 8.7 9.3 1.3 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal SPX PF03105.19 CRK27075.1 - 6.4 6.6 14.4 7.9 6.3 14.4 1.1 1 0 0 1 1 1 0 SPX domain EGF_2 PF07974.13 CRK27077.1 - 2.7 8.5 9.4 4.6 7.7 9.4 1.4 1 0 0 1 1 1 0 EGF-like domain Flavi_M PF01004.19 CRK27078.1 - 0.016 15.0 0.5 0.032 14.0 0.5 1.5 1 0 0 1 1 1 0 Flavivirus envelope glycoprotein M MscS_TM PF12794.7 CRK27078.1 - 0.063 12.1 0.0 0.085 11.7 0.0 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 ketoacyl-synt PF00109.26 CRK27079.1 - 4.1e-63 213.3 0.0 9.1e-63 212.2 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 CRK27079.1 - 4e-46 157.6 0.0 6.5e-46 156.9 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 CRK27079.1 - 9.8e-41 140.3 0.0 1.8e-40 139.4 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 CRK27079.1 - 3.8e-40 137.7 0.8 6.2e-20 71.9 1.0 2.6 2 0 0 2 2 2 2 KR domain Ketoacyl-synt_C PF02801.22 CRK27079.1 - 2.9e-30 104.7 0.0 7.4e-30 103.4 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 CRK27079.1 - 1.2e-17 64.3 0.0 2.8e-17 63.2 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 CRK27079.1 - 1.3e-11 44.3 0.0 2.8e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase PP-binding PF00550.25 CRK27079.1 - 3.2e-07 30.6 0.0 8.8e-07 29.2 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short_C2 PF13561.6 CRK27079.1 - 8.5e-07 28.8 0.0 3.9e-06 26.6 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ADH_zinc_N PF00107.26 CRK27079.1 - 0.0033 17.4 0.0 0.032 14.2 0.0 2.8 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CRK27079.1 - 0.03 14.2 0.1 0.082 12.8 0.1 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.23 CRK27079.1 - 0.056 12.8 0.1 0.14 11.5 0.1 1.6 1 0 0 1 1 1 0 Thiolase, N-terminal domain MFS_1 PF07690.16 CRK27080.1 - 4.7e-29 101.4 41.3 8.6e-29 100.5 41.3 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily ATP-synt_10 PF05176.14 CRK27081.1 - 1.6e-56 191.4 0.0 2.6e-56 190.7 0.0 1.2 1 0 0 1 1 1 1 ATP10 protein PAS_4 PF08448.10 CRK27081.1 - 0.00016 21.9 0.0 0.0009 19.5 0.0 2.4 3 0 0 3 3 3 1 PAS fold Helo_like_N PF17111.5 CRK27081.1 - 0.091 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins 2-oxoacid_dh PF00198.23 CRK27083.1 - 3.8e-72 242.5 0.1 6.5e-72 241.7 0.1 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 CRK27083.1 - 8.3e-18 64.0 0.1 1.4e-17 63.3 0.1 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 CRK27083.1 - 1.8e-13 50.6 0.2 5.4e-13 49.1 0.2 1.9 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 CRK27083.1 - 0.022 14.6 0.1 0.094 12.6 0.1 2.0 2 0 0 2 2 2 0 Biotin-lipoyl like Ribosomal_60s PF00428.19 CRK27083.1 - 5.8 7.6 14.9 7.7 7.2 9.9 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein ATP-synt_10 PF05176.14 CRK27084.1 - 3.2e-68 229.8 0.0 4.1e-68 229.4 0.0 1.0 1 0 0 1 1 1 1 ATP10 protein Phage_TAC_6 PF09550.10 CRK27085.1 - 0.025 15.0 0.4 0.03 14.8 0.4 1.2 1 0 0 1 1 1 0 Phage tail assembly chaperone protein, TAC V-SNARE_C PF12352.8 CRK27086.1 - 1.1e-11 44.9 0.5 1.1e-11 44.9 0.5 2.8 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Het-C PF07217.11 CRK27086.1 - 0.003 16.2 1.6 0.041 12.4 0.1 2.0 1 1 1 2 2 2 1 Heterokaryon incompatibility protein Het-C PDZ_5 PF17817.1 CRK27086.1 - 0.14 12.4 0.4 0.42 10.9 0.4 1.7 1 0 0 1 1 1 0 PDZ domain Spc7 PF08317.11 CRK27086.1 - 0.15 10.9 7.7 0.045 12.6 5.1 1.4 2 0 0 2 2 2 0 Spc7 kinetochore protein UPF0184 PF03670.13 CRK27086.1 - 0.25 11.8 2.9 1.3 9.5 0.2 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) STAT_alpha PF01017.20 CRK27086.1 - 0.27 11.1 4.3 0.62 9.9 0.7 2.5 1 1 0 2 2 2 0 STAT protein, all-alpha domain Fib_alpha PF08702.10 CRK27086.1 - 0.54 10.4 6.7 0.31 11.2 1.3 2.1 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family CHDCT2 PF08074.11 CRK27086.1 - 1.1 9.4 6.1 3.3 7.9 3.9 2.5 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain DivIC PF04977.15 CRK27086.1 - 4.3 7.2 6.1 25 4.7 4.3 2.7 2 0 0 2 2 2 0 Septum formation initiator Ribosomal_L29 PF00831.23 CRK27087.1 - 5.3e-18 64.7 0.3 5.3e-18 64.7 0.3 1.8 2 0 0 2 2 2 1 Ribosomal L29 protein Trp_syntA PF00290.20 CRK27088.1 - 0.17 10.7 0.0 0.23 10.3 0.0 1.1 1 0 0 1 1 1 0 Tryptophan synthase alpha chain Stk19 PF10494.9 CRK27089.1 - 2.7e-67 227.0 0.0 3.3e-67 226.7 0.0 1.1 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 F-box-like PF12937.7 CRK27090.1 - 0.0032 17.3 0.0 0.0062 16.4 0.0 1.5 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 CRK27090.1 - 0.44 10.7 2.3 9.3 6.6 0.2 3.6 4 0 0 4 4 4 0 Leucine Rich repeat Sulfate_transp PF00916.20 CRK27091.1 - 4.3e-56 190.3 14.2 6.3e-56 189.8 14.2 1.1 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 CRK27091.1 - 1.9e-12 47.0 0.0 3.6e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 CRK27091.1 - 3.7e-11 42.7 0.1 6.3e-11 41.9 0.1 1.4 1 0 0 1 1 1 1 STAS domain EF1_GNE PF00736.19 CRK27092.1 - 1.5e-32 111.6 0.8 2.3e-32 111.0 0.8 1.3 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 CRK27092.1 - 2.2e-14 53.6 9.6 2.2e-14 53.6 9.6 2.4 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.6 CRK27092.1 - 0.0013 18.9 0.7 0.0067 16.6 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CRK27092.1 - 0.0093 16.2 1.3 0.024 14.9 0.0 2.3 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CRK27092.1 - 0.078 13.0 0.7 0.5 10.4 0.7 2.2 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Proteasom_Rpn13 PF04683.13 CRK27093.1 - 9.2e-28 96.6 0.0 1.4e-27 96.1 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RPN13_C PF16550.5 CRK27093.1 - 3.2e-08 33.7 0.0 1.8e-07 31.3 0.0 2.1 1 1 0 1 1 1 1 UCH-binding domain DUF2301 PF10063.9 CRK27094.1 - 0.028 14.9 0.2 0.046 14.2 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized integral membrane protein (DUF2301) HofP PF10748.9 CRK27094.1 - 0.21 11.1 0.3 0.91 9.1 0.1 2.0 2 0 0 2 2 2 0 DNA utilization proteins HofP DUF3405 PF11885.8 CRK27095.1 - 1e-226 753.6 0.6 1.5e-226 753.0 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Arf PF00025.21 CRK27096.1 - 2.6e-80 268.0 0.3 3e-80 267.8 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CRK27096.1 - 1.7e-14 54.1 0.0 2.3e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CRK27096.1 - 2e-14 53.4 0.0 2.5e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 CRK27096.1 - 2.6e-13 49.9 1.5 2e-09 37.1 0.5 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 CRK27096.1 - 3.4e-13 49.5 0.0 3.8e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 CRK27096.1 - 1.2e-10 41.1 0.0 1.6e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CRK27096.1 - 2.9e-06 27.3 0.0 4.5e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 CRK27096.1 - 0.0095 15.3 1.0 0.028 13.7 1.0 1.8 1 1 0 1 1 1 1 6-phosphofructo-2-kinase EMP24_GP25L PF01105.24 CRK27097.1 - 7.3e-44 149.9 0.0 8.6e-44 149.7 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD NuiA PF07924.11 CRK27097.1 - 0.096 13.1 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 Nuclease A inhibitor-like protein AAA_2 PF07724.14 CRK27098.1 - 5.4e-44 150.3 0.0 4.9e-43 147.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.9 CRK27098.1 - 2.1e-24 85.4 0.2 2.1e-24 85.4 0.2 2.2 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 CRK27098.1 - 1.8e-17 64.0 1.4 5.9e-09 36.5 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CRK27098.1 - 5.4e-13 49.1 0.1 4.9e-09 36.3 0.0 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CRK27098.1 - 1.6e-09 38.4 3.2 0.0021 18.5 0.1 4.2 2 2 1 4 4 4 2 AAA ATPase domain AAA_lid_9 PF17871.1 CRK27098.1 - 5.6e-09 35.9 4.3 5.6e-09 35.9 4.3 2.5 1 1 1 2 2 2 1 AAA lid domain Sigma54_activat PF00158.26 CRK27098.1 - 4.6e-07 29.7 0.1 0.00052 19.8 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_22 PF13401.6 CRK27098.1 - 4.8e-07 30.1 1.3 0.035 14.4 0.1 3.6 2 2 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 CRK27098.1 - 5.8e-06 26.4 1.6 0.49 10.3 0.1 3.9 2 2 1 3 3 3 1 ATPase domain predominantly from Archaea NACHT PF05729.12 CRK27098.1 - 3.5e-05 23.8 0.0 0.19 11.7 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_14 PF13173.6 CRK27098.1 - 8.6e-05 22.6 0.0 0.44 10.6 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA_7 PF12775.7 CRK27098.1 - 0.00014 21.5 0.0 0.62 9.6 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 CRK27098.1 - 0.00027 20.7 0.2 0.38 10.5 0.0 2.7 2 1 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 CRK27098.1 - 0.0014 19.2 0.1 0.28 11.7 0.0 3.0 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 CRK27098.1 - 0.0046 16.4 0.1 2.4 7.5 0.0 3.0 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI RsgA_GTPase PF03193.16 CRK27098.1 - 0.0046 16.9 0.0 1.6 8.6 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase ERM PF00769.19 CRK27098.1 - 0.0049 16.7 7.5 0.009 15.8 7.5 1.4 1 0 0 1 1 1 1 Ezrin/radixin/moesin family AAA_24 PF13479.6 CRK27098.1 - 0.0051 16.6 0.0 1.1 9.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CRK27098.1 - 0.0054 17.1 0.0 0.99 9.8 0.0 3.1 2 1 0 2 2 2 1 RNA helicase AAA_30 PF13604.6 CRK27098.1 - 0.007 16.1 0.4 0.57 9.9 0.0 3.2 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.27 CRK27098.1 - 0.0076 16.8 4.3 0.28 11.7 0.0 3.4 2 1 0 2 2 2 1 ABC transporter Roc PF08477.13 CRK27098.1 - 0.0076 16.5 0.1 3.2 8.0 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase SRP54 PF00448.22 CRK27098.1 - 0.014 15.0 0.0 0.59 9.7 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_28 PF13521.6 CRK27098.1 - 0.014 15.6 0.7 6.7 6.9 0.0 3.1 3 0 0 3 3 2 0 AAA domain ResIII PF04851.15 CRK27098.1 - 0.016 15.2 0.1 13 5.8 0.0 3.4 2 1 0 3 3 3 0 Type III restriction enzyme, res subunit TsaE PF02367.17 CRK27098.1 - 0.016 15.2 0.0 9.3 6.3 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PduV-EutP PF10662.9 CRK27098.1 - 0.02 14.6 0.2 0.82 9.4 0.0 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation PhoH PF02562.16 CRK27098.1 - 0.023 14.2 0.0 0.54 9.7 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA_33 PF13671.6 CRK27098.1 - 0.025 14.7 0.0 8.3 6.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 CRK27098.1 - 0.026 13.8 0.5 2 7.7 0.0 3.1 3 0 0 3 3 3 0 Zeta toxin AAA_25 PF13481.6 CRK27098.1 - 0.029 13.9 0.2 0.73 9.4 0.0 2.7 2 1 0 2 2 2 0 AAA domain DUF815 PF05673.13 CRK27098.1 - 0.049 12.8 0.6 0.94 8.6 0.3 2.9 2 2 0 2 2 2 0 Protein of unknown function (DUF815) PilJ PF13675.6 CRK27098.1 - 0.13 12.3 1.0 1.6 8.8 1.5 2.5 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term OEP PF02321.18 CRK27098.1 - 0.15 11.9 4.0 1.1 9.0 4.6 2.0 2 0 0 2 2 2 0 Outer membrane efflux protein AAA_29 PF13555.6 CRK27098.1 - 0.18 11.6 0.1 7.2 6.4 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain UvrD-helicase PF00580.21 CRK27098.1 - 0.24 10.9 2.6 0.72 9.3 0.1 2.1 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain Seryl_tRNA_N PF02403.22 CRK27098.1 - 0.28 11.4 12.6 0.21 11.8 9.9 2.3 2 0 0 2 2 1 0 Seryl-tRNA synthetase N-terminal domain CENP-F_leu_zip PF10473.9 CRK27098.1 - 0.28 11.2 15.0 2.4 8.2 14.4 2.2 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4407 PF14362.6 CRK27098.1 - 0.31 10.4 6.3 0.57 9.5 6.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_19 PF13245.6 CRK27098.1 - 0.41 11.0 6.9 0.92 9.8 0.0 3.7 3 2 1 4 4 4 0 AAA domain GrpE PF01025.19 CRK27098.1 - 0.49 10.0 6.0 1.2 8.8 6.0 1.7 1 0 0 1 1 1 0 GrpE DegS PF05384.11 CRK27098.1 - 0.57 9.6 9.7 2.1 7.8 7.2 2.7 2 1 0 2 2 2 0 Sensor protein DegS UPF0242 PF06785.11 CRK27098.1 - 0.65 10.1 7.5 1.3 9.1 7.5 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus AAA_21 PF13304.6 CRK27098.1 - 1.4 8.7 3.6 2.6 7.8 0.1 2.9 3 1 1 4 4 3 0 AAA domain, putative AbiEii toxin, Type IV TA system ADIP PF11559.8 CRK27098.1 - 2.2 8.4 9.7 4.8 7.3 9.7 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding NPV_P10 PF05531.12 CRK27098.1 - 2.3 8.7 5.1 2.1 8.9 2.1 2.5 2 1 0 2 2 1 0 Nucleopolyhedrovirus P10 protein DUF4061 PF13270.6 CRK27098.1 - 2.8 8.3 6.8 21 5.5 0.2 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4061) APG6_N PF17675.1 CRK27098.1 - 5.5 7.5 16.1 15 6.1 16.1 1.7 1 0 0 1 1 1 0 Apg6 coiled-coil region Ribosomal_L6e PF01159.19 CRK27099.1 - 7.5e-40 135.9 0.3 7.5e-40 135.9 0.3 1.5 2 0 0 2 2 2 1 Ribosomal protein L6e Peptidase_M49 PF03571.15 CRK27100.1 - 3.9e-230 764.9 0.0 1.4e-229 763.1 0.0 1.9 2 1 0 2 2 2 1 Peptidase family M49 SKI PF01202.22 CRK27102.1 - 1e-10 41.9 0.0 1.4e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.6 CRK27102.1 - 3.2e-10 40.3 0.0 4.8e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CRK27102.1 - 3.3e-10 40.6 0.0 7.1e-10 39.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 CRK27102.1 - 2e-06 28.3 0.4 9.2e-06 26.1 0.4 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 CRK27102.1 - 2.8e-06 27.8 0.0 7.2e-06 26.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 CRK27102.1 - 3.6e-05 23.8 0.0 6.5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 CRK27102.1 - 5.8e-05 23.5 0.0 7.4e-05 23.2 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain Cytidylate_kin PF02224.18 CRK27102.1 - 7e-05 22.7 0.1 0.0011 18.7 0.0 2.1 2 0 0 2 2 2 1 Cytidylate kinase dNK PF01712.19 CRK27102.1 - 0.00012 22.0 0.0 0.29 11.0 0.1 2.3 2 0 0 2 2 2 2 Deoxynucleoside kinase NACHT PF05729.12 CRK27102.1 - 0.00021 21.2 0.0 0.00039 20.4 0.0 1.4 1 0 0 1 1 1 1 NACHT domain PRK PF00485.18 CRK27102.1 - 0.00043 20.1 0.0 0.0031 17.3 0.0 2.0 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_22 PF13401.6 CRK27102.1 - 0.00057 20.2 0.0 0.0011 19.2 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_28 PF13521.6 CRK27102.1 - 0.0015 18.8 0.0 0.0023 18.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 CRK27102.1 - 0.0031 17.5 0.0 0.0062 16.5 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 CRK27102.1 - 0.0031 17.4 0.3 0.026 14.5 0.0 2.0 2 0 0 2 2 2 1 NTPase AAA_5 PF07728.14 CRK27102.1 - 0.0066 16.4 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 CRK27102.1 - 0.0086 16.1 0.0 0.026 14.5 0.0 1.8 1 1 1 2 2 2 1 AAA domain TsaE PF02367.17 CRK27102.1 - 0.011 15.7 0.0 0.083 12.9 0.0 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 CRK27102.1 - 0.011 16.1 0.0 0.02 15.3 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.6 CRK27102.1 - 0.014 15.7 0.0 0.03 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 CRK27102.1 - 0.016 14.4 0.0 0.025 13.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.27 CRK27102.1 - 0.019 15.5 0.0 0.034 14.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter RuvB_N PF05496.12 CRK27102.1 - 0.022 14.5 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Thymidylate_kin PF02223.17 CRK27102.1 - 0.027 14.2 0.1 2.9 7.5 0.0 2.3 2 0 0 2 2 2 0 Thymidylate kinase Mg_chelatase PF01078.21 CRK27102.1 - 0.044 13.2 0.0 0.076 12.4 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI CoaE PF01121.20 CRK27102.1 - 0.049 13.3 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 Dephospho-CoA kinase Cytidylate_kin2 PF13189.6 CRK27102.1 - 0.054 13.6 0.0 0.27 11.4 0.0 2.0 2 1 0 2 2 2 0 Cytidylate kinase-like family AAA_30 PF13604.6 CRK27102.1 - 0.055 13.2 0.0 0.097 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 CRK27102.1 - 0.063 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein APS_kinase PF01583.20 CRK27102.1 - 0.075 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_7 PF12775.7 CRK27102.1 - 0.082 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 CRK27102.1 - 0.095 12.0 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Thermopsin PF05317.11 CRK27102.1 - 0.1 12.1 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Thermopsin DNA_pol3_delta2 PF13177.6 CRK27102.1 - 0.12 12.2 0.0 0.28 11.0 0.0 1.5 1 1 0 1 1 1 0 DNA polymerase III, delta subunit Viral_helicase1 PF01443.18 CRK27102.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_23 PF13476.6 CRK27102.1 - 0.13 12.7 0.0 0.23 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain HATPase_c PF02518.26 CRK27103.1 - 9.2e-21 74.5 0.0 3.7e-20 72.5 0.0 2.1 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 CRK27103.1 - 1.9e-17 63.5 0.6 1e-11 45.0 0.0 3.1 2 1 1 3 3 3 2 Response regulator receiver domain HisKA PF00512.25 CRK27103.1 - 1.9e-08 34.2 0.0 8.1e-08 32.2 0.0 2.1 1 1 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Dabb PF07876.12 CRK27103.1 - 2.8e-06 27.9 0.0 4.7e-05 23.9 0.0 2.5 1 1 0 1 1 1 1 Stress responsive A/B Barrel Domain PAS_9 PF13426.7 CRK27103.1 - 0.0098 16.1 0.0 0.033 14.5 0.0 1.9 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 CRK27103.1 - 0.085 13.1 0.0 0.51 10.6 0.0 2.4 3 0 0 3 3 3 0 PAS fold YIF1 PF03878.15 CRK27104.1 - 5.2e-98 327.3 0.4 8e-98 326.7 0.4 1.3 1 0 0 1 1 1 1 YIF1 Mpv17_PMP22 PF04117.12 CRK27104.1 - 1.1e-12 48.0 0.4 1.1e-12 48.0 0.4 2.2 2 0 0 2 2 2 1 Mpv17 / PMP22 family Yip1 PF04893.17 CRK27104.1 - 0.0015 18.3 5.2 0.0015 18.3 5.2 2.4 3 0 0 3 3 3 1 Yip1 domain SKI PF01202.22 CRK27105.1 - 1.3e-10 41.7 0.0 1.7e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.6 CRK27105.1 - 1.9e-10 41.4 0.0 3.8e-10 40.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CRK27105.1 - 5.3e-10 39.6 0.0 8e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 CRK27105.1 - 7.9e-07 29.6 0.0 1.7e-06 28.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 CRK27105.1 - 1.8e-06 28.4 0.4 8.3e-06 26.3 0.4 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 CRK27105.1 - 3.6e-05 23.8 0.0 6.4e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 CRK27105.1 - 4.8e-05 23.8 0.0 6.3e-05 23.4 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain Cytidylate_kin PF02224.18 CRK27105.1 - 7.6e-05 22.5 0.1 0.0013 18.5 0.0 2.1 2 0 0 2 2 2 1 Cytidylate kinase dNK PF01712.19 CRK27105.1 - 0.00012 22.1 0.0 0.28 11.0 0.1 2.3 2 0 0 2 2 2 2 Deoxynucleoside kinase NACHT PF05729.12 CRK27105.1 - 0.00021 21.2 0.0 0.00038 20.4 0.0 1.4 1 0 0 1 1 1 1 NACHT domain PRK PF00485.18 CRK27105.1 - 0.00047 19.9 0.0 0.0034 17.1 0.0 2.0 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_28 PF13521.6 CRK27105.1 - 0.0005 20.4 0.0 0.00075 19.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CRK27105.1 - 0.00051 20.3 0.0 0.001 19.3 0.0 1.6 2 0 0 2 2 1 1 AAA domain NTPase_1 PF03266.15 CRK27105.1 - 0.0026 17.7 0.2 0.024 14.6 0.0 2.0 2 0 0 2 2 2 1 NTPase ATPase_2 PF01637.18 CRK27105.1 - 0.0028 17.6 0.0 0.0054 16.7 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_5 PF07728.14 CRK27105.1 - 0.0065 16.5 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 CRK27105.1 - 0.0088 16.1 0.0 0.021 14.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain TsaE PF02367.17 CRK27105.1 - 0.01 15.8 0.0 0.081 12.9 0.0 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 CRK27105.1 - 0.012 15.9 0.0 0.022 15.1 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.6 CRK27105.1 - 0.014 15.7 0.0 0.029 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 CRK27105.1 - 0.015 14.5 0.0 0.024 13.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.27 CRK27105.1 - 0.019 15.4 0.0 0.034 14.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter RuvB_N PF05496.12 CRK27105.1 - 0.021 14.6 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Thymidylate_kin PF02223.17 CRK27105.1 - 0.022 14.4 0.0 2.8 7.6 0.0 2.3 2 0 0 2 2 2 0 Thymidylate kinase Mg_chelatase PF01078.21 CRK27105.1 - 0.044 13.2 0.0 0.077 12.4 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI CoaE PF01121.20 CRK27105.1 - 0.045 13.4 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 Dephospho-CoA kinase Cytidylate_kin2 PF13189.6 CRK27105.1 - 0.052 13.7 0.0 0.22 11.6 0.0 2.0 2 0 0 2 2 2 0 Cytidylate kinase-like family AAA_30 PF13604.6 CRK27105.1 - 0.054 13.2 0.0 0.096 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 CRK27105.1 - 0.058 13.3 0.0 0.084 12.8 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase T2SSE PF00437.20 CRK27105.1 - 0.06 12.4 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 CRK27105.1 - 0.08 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 CRK27105.1 - 0.082 12.2 0.0 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin DNA_pol3_delta2 PF13177.6 CRK27105.1 - 0.11 12.3 0.0 0.13 12.1 0.0 1.5 1 1 0 1 1 1 0 DNA polymerase III, delta subunit Viral_helicase1 PF01443.18 CRK27105.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_23 PF13476.6 CRK27105.1 - 0.12 12.8 0.0 0.22 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Thermopsin PF05317.11 CRK27105.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Thermopsin ADK PF00406.22 CRK27105.1 - 0.15 12.1 0.1 2.5 8.2 0.0 2.1 2 0 0 2 2 2 0 Adenylate kinase AAA_25 PF13481.6 CRK27105.1 - 0.15 11.6 0.4 0.37 10.3 0.2 1.9 1 1 0 1 1 1 0 AAA domain 2-oxoacid_dh PF00198.23 CRK27106.1 - 3.3e-72 242.7 0.1 5.6e-72 242.0 0.1 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 CRK27106.1 - 7.8e-18 64.1 0.1 1.3e-17 63.4 0.1 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 CRK27106.1 - 6.5e-13 48.8 0.3 1.8e-12 47.4 0.3 1.8 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 CRK27106.1 - 0.024 14.5 0.1 0.088 12.7 0.1 1.9 2 0 0 2 2 2 0 Biotin-lipoyl like DEC-1_N PF04625.13 CRK27106.1 - 1.8 7.5 16.7 0.48 9.4 2.8 2.2 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region CAP_N PF01213.19 CRK27106.1 - 6.7 6.1 13.2 1.9 7.9 3.6 2.3 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Ribosomal_L29 PF00831.23 CRK27107.1 - 5.7e-18 64.6 5.4 2e-17 62.9 0.3 2.4 2 0 0 2 2 2 1 Ribosomal L29 protein ATP-synt_10 PF05176.14 CRK27107.1 - 9.6e-07 28.3 0.0 2.1e-06 27.2 0.0 1.5 1 1 0 1 1 1 1 ATP10 protein Tctex-1 PF03645.13 CRK27107.1 - 0.13 12.5 0.1 0.29 11.4 0.1 1.6 1 0 0 1 1 1 0 Tctex-1 family HTH_12 PF08461.10 CRK27107.1 - 0.13 12.2 1.1 0.35 10.9 1.1 1.7 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain YopE_N PF09020.10 CRK27107.1 - 0.37 11.1 1.6 0.65 10.2 0.1 2.1 2 1 1 3 3 3 0 YopE, N terminal CHDCT2 PF08074.11 CRK27108.1 - 0.025 14.8 3.2 0.21 11.8 3.2 1.9 1 1 0 1 1 1 0 CHDCT2 (NUC038) domain Het-C PF07217.11 CRK27108.1 - 0.094 11.2 0.0 0.11 11.0 0.0 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C Syntaxin-6_N PF09177.11 CRK27108.1 - 0.25 11.9 5.1 1.1 9.8 2.3 2.0 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Spc7 PF08317.11 CRK27108.1 - 0.46 9.3 5.5 0.27 10.1 3.6 1.6 2 0 0 2 2 2 0 Spc7 kinetochore protein zf-C2H2_4 PF13894.6 CRK27110.1 - 4.9e-14 51.8 20.1 0.00023 21.7 1.1 6.2 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2 PF00096.26 CRK27110.1 - 1.9e-13 50.1 36.1 2e-05 24.8 0.9 7.2 6 1 0 6 6 5 4 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 CRK27110.1 - 9.7e-08 32.1 11.1 0.039 14.3 0.4 4.8 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 CRK27110.1 - 8.5e-07 29.1 22.3 0.00015 22.0 0.1 6.0 4 1 1 5 5 5 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 CRK27110.1 - 6.6e-06 26.0 11.4 0.00084 19.3 0.3 3.8 4 0 0 4 4 4 2 C2H2-type zinc finger zf-met PF12874.7 CRK27110.1 - 0.0048 17.2 9.9 4.4 7.8 0.1 4.9 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 CRK27110.1 - 0.0083 16.0 3.0 0.11 12.5 0.2 2.8 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-C2H2_9 PF16293.5 CRK27110.1 - 0.029 14.2 1.7 21 5.1 0.0 4.0 3 1 1 4 4 4 0 C2H2 type zinc-finger (1 copy) zf-C2H2_2 PF12756.7 CRK27110.1 - 0.046 14.1 11.2 0.53 10.6 0.4 4.5 3 1 1 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-C2HE PF16278.5 CRK27110.1 - 0.074 13.5 6.8 18 5.9 6.4 3.0 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf-H2C2_5 PF13909.6 CRK27110.1 - 0.091 12.5 0.4 0.091 12.5 0.4 4.9 5 0 0 5 5 4 0 C2H2-type zinc-finger domain zf-C2H2_3rep PF18868.1 CRK27110.1 - 0.1 13.2 12.9 0.3 11.8 3.4 3.3 2 1 2 4 4 4 0 Zinc finger C2H2-type, 3 repeats zf_ZIC PF18366.1 CRK27110.1 - 0.21 11.7 6.4 4.5 7.4 0.1 4.4 4 0 0 4 4 4 0 Zic proteins zinc finger domain DUF3235 PF11574.8 CRK27110.1 - 1.1 10.1 8.8 4.3 8.2 8.8 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3235) Chorion_2 PF03964.15 CRK27110.1 - 1.3 9.9 6.0 0.6 11.0 2.4 2.3 2 0 0 2 2 2 0 Chorion family 2 zf-BED PF02892.15 CRK27110.1 - 1.7 8.8 16.9 1.5 8.9 1.6 4.0 2 2 2 4 4 4 0 BED zinc finger Actin_micro PF17003.5 CRK27110.1 - 2.7 7.1 6.6 7.6 5.6 1.2 3.3 2 1 1 3 3 3 0 Putative actin-like family zf-C2H2_4 PF13894.6 CRK27111.1 - 0.003 18.2 8.0 0.16 12.9 0.4 4.3 3 0 0 3 3 3 1 C2H2-type zinc finger EPL1 PF10513.9 CRK27111.1 - 0.095 13.1 15.6 0.35 11.3 12.0 3.1 2 1 0 3 3 3 0 Enhancer of polycomb-like Exonuc_VII_L PF02601.15 CRK27111.1 - 5 6.6 25.9 8.5 5.8 25.9 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Membralin PF09746.9 CRK27111.1 - 6.2 5.7 15.3 9.2 5.2 15.3 1.1 1 0 0 1 1 1 0 Tumour-associated protein GREB1 PF15782.5 CRK27111.1 - 6.9 3.6 27.2 10 3.0 27.2 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Helicase_C PF00271.31 CRK27113.1 - 1.2e-20 73.9 0.0 2.3e-20 73.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain GCIP PF13324.6 CRK27113.1 - 0.054 13.1 0.6 0.078 12.6 0.6 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting BSP_II PF05432.11 CRK27113.1 - 0.16 11.7 4.9 0.21 11.2 4.9 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Med19 PF10278.9 CRK27113.1 - 0.46 10.4 5.5 0.73 9.8 5.5 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 HCNGP PF07818.13 CRK27114.1 - 2.1e-23 82.8 0.0 9.7e-23 80.6 0.0 2.1 1 1 0 1 1 1 1 HCNGP-like protein DEAD PF00270.29 CRK27115.1 - 4.9e-49 166.5 0.0 1.2e-48 165.3 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF3712 PF12505.8 CRK27115.1 - 2e-26 92.7 1.6 4.3e-26 91.6 1.6 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3712) ResIII PF04851.15 CRK27115.1 - 0.051 13.6 0.0 0.099 12.6 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit HCNGP PF07818.13 CRK27116.1 - 2.3e-23 82.6 0.0 1.7e-22 79.9 0.0 2.2 1 1 0 1 1 1 1 HCNGP-like protein FMN_dh PF01070.18 CRK27117.1 - 2.3e-106 355.7 0.1 4.7e-106 354.7 0.1 1.5 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 CRK27117.1 - 2e-32 111.2 0.1 1.3e-18 66.9 0.0 2.6 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DUF3712 PF12505.8 CRK27117.1 - 1.5e-26 93.1 1.3 3.2e-26 92.0 1.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3712) Glu_synthase PF01645.17 CRK27117.1 - 2.4e-06 26.9 0.1 4.4e-06 26.1 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 CRK27117.1 - 8.7e-05 21.7 0.1 0.00027 20.1 0.0 1.7 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain LRR19-TM PF15176.6 CRK27117.1 - 0.11 12.5 0.5 0.24 11.4 0.5 1.5 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain DHO_dh PF01180.21 CRK27117.1 - 0.11 11.6 0.8 0.17 11.1 0.1 1.6 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase Ribul_P_3_epim PF00834.19 CRK27117.1 - 0.13 11.7 0.0 0.28 10.5 0.0 1.6 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family HSCB_C PF07743.13 CRK27118.1 - 7.4e-19 68.0 0.4 7.4e-19 68.0 0.4 2.8 3 0 0 3 3 3 1 HSCB C-terminal oligomerisation domain PCI PF01399.27 CRK27118.1 - 1.2e-11 45.0 0.0 2.9e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 PCI domain DnaJ PF00226.31 CRK27118.1 - 1.9e-06 27.9 0.2 4e-06 26.9 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain Lipase_GDSL_2 PF13472.6 CRK27119.1 - 3.7e-20 73.0 0.0 5.2e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 CRK27119.1 - 6.5e-10 39.3 0.0 8.7e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase GPHR_N PF12537.8 CRK27119.1 - 0.14 12.3 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 The Golgi pH Regulator (GPHR) Family N-terminal LRR_8 PF13855.6 CRK27120.1 - 0.033 13.9 1.1 1.2 9.0 0.2 3.1 3 0 0 3 3 3 0 Leucine rich repeat LRR_4 PF12799.7 CRK27120.1 - 0.1 13.1 0.7 22 5.7 0.1 3.6 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) Glyco_hydro_16 PF00722.21 CRK27121.1 - 6.3e-09 35.5 0.0 4.8e-07 29.4 0.0 2.4 2 0 0 2 2 2 2 Glycosyl hydrolases family 16 Hum_adeno_E3A PF05393.11 CRK27122.1 - 0.44 10.5 0.1 0.44 10.5 0.1 2.7 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein DUF805 PF05656.14 CRK27122.1 - 5.1 7.6 7.6 17 5.9 7.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF805) DUF3292 PF11696.8 CRK27123.1 - 1.1e-193 645.3 0.0 1e-170 569.3 0.0 2.7 1 1 1 2 2 2 2 Protein of unknown function (DUF3292) Glyco_transf_34 PF05637.12 CRK27124.1 - 1.3e-61 208.4 0.2 1.7e-61 208.0 0.2 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Bac_rhamnosid_N PF08531.10 CRK27124.1 - 1.2e-35 122.8 2.6 1.9e-34 118.9 0.0 2.6 2 1 1 3 3 3 2 Alpha-L-rhamnosidase N-terminal domain ArabFuran-catal PF09206.11 CRK27126.1 - 3.9e-134 446.9 16.7 9.3e-134 445.7 16.7 1.6 1 1 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic AbfB PF05270.13 CRK27126.1 - 1.6e-52 177.2 1.4 3.5e-52 176.1 1.4 1.6 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) domain RPE65 PF03055.15 CRK27127.1 - 3.5e-05 23.2 0.0 3.7e-05 23.1 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Sugar_tr PF00083.24 CRK27128.1 - 8.3e-62 209.5 23.0 9.3e-62 209.3 23.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK27128.1 - 6.4e-10 38.5 37.8 0.00022 20.3 22.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 CRK27131.1 - 3.5e-09 36.1 0.1 5.4e-09 35.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK27131.1 - 8.5e-08 32.2 14.1 1.6e-07 31.3 14.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 CRK27133.1 - 1.1e-22 80.6 0.0 2.9e-22 79.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK27133.1 - 6e-11 42.1 0.0 9.6e-11 41.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CRK27133.1 - 0.00027 20.3 0.0 0.00051 19.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CRK27133.1 - 0.088 11.6 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Pox_ser-thr_kin PF05445.11 CRK27133.1 - 0.22 10.4 0.0 0.35 9.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase FOXP-CC PF16159.5 CRK27135.1 - 0.66 10.7 5.7 0.62 10.7 0.2 2.9 3 0 0 3 3 3 0 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 CRK27135.1 - 2.2 9.4 14.9 14 6.9 2.6 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-Di19 PF05605.12 CRK27135.1 - 3.9 7.8 12.3 0.55 10.6 0.2 2.6 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding HET PF06985.11 CRK27155.1 - 1.2e-11 45.1 2.2 1.4e-11 44.9 1.1 1.7 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Peptidase_S8 PF00082.22 CRK27157.1 - 6.1e-33 114.4 13.9 1.2e-32 113.3 13.9 1.4 1 1 0 1 1 1 1 Subtilase family Peptidase_S8 PF00082.22 CRK27158.1 - 1.1e-32 113.5 14.1 2.2e-32 112.5 14.1 1.4 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 CRK27158.1 - 0.097 13.4 0.1 22 5.8 0.0 2.5 1 1 1 2 2 2 0 Peptidase inhibitor I9 SQS_PSY PF00494.19 CRK27159.1 - 1.5e-35 123.0 0.0 2.2e-35 122.5 0.0 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase Cbl_N2 PF02761.14 CRK27159.1 - 0.14 12.9 0.8 37 5.1 0.0 2.9 3 0 0 3 3 3 0 CBL proto-oncogene N-terminus, EF hand-like domain RmlD_sub_bind PF04321.17 CRK27160.1 - 2.4e-13 49.8 0.0 4.7e-13 48.9 0.0 1.6 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 CRK27160.1 - 6e-11 42.3 0.0 1e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 CRK27160.1 - 0.00095 18.4 0.0 0.0014 17.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 CRK27160.1 - 0.024 14.0 0.0 0.15 11.4 0.0 2.1 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 CRK27160.1 - 0.032 13.2 0.0 0.072 12.1 0.0 1.5 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family DnaJ-X PF14308.6 CRK27161.1 - 9.6e-71 237.6 0.5 9.6e-71 237.6 0.5 2.1 2 1 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 CRK27161.1 - 8.9e-38 128.2 3.8 2.8e-26 91.4 1.0 2.5 2 0 0 2 2 2 2 DnaJ domain Ribonuc_red_lgC PF02867.15 CRK27161.1 - 0.052 12.1 0.0 0.089 11.3 0.0 1.3 1 0 0 1 1 1 0 Ribonucleotide reductase, barrel domain FHA PF00498.26 CRK27162.1 - 1.8e-09 37.8 0.0 2.2e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CRK27162.1 - 0.011 16.0 0.0 0.26 11.6 0.0 2.1 1 1 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain Mannosyl_trans PF05007.13 CRK27163.1 - 1.8e-75 254.1 11.0 2.4e-75 253.8 11.0 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 CRK27163.1 - 1.3e-12 47.5 9.2 7.7e-12 44.9 9.2 2.0 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U GT87 PF09594.10 CRK27163.1 - 2.8e-05 24.0 20.5 2.8e-05 24.0 20.5 2.6 2 1 1 3 3 3 1 Glycosyltransferase family 87 Translin PF01997.16 CRK27164.1 - 1.3e-58 198.4 0.0 1.5e-58 198.2 0.0 1.0 1 0 0 1 1 1 1 Translin family CdvA PF18822.1 CRK27164.1 - 0.027 14.3 0.4 12 5.8 0.1 3.0 3 0 0 3 3 3 0 CdvA-like coiled-coil domain TMEM154 PF15102.6 CRK27165.1 - 0.0031 17.4 0.0 0.0059 16.5 0.0 1.4 1 0 0 1 1 1 1 TMEM154 protein family DUF4448 PF14610.6 CRK27165.1 - 0.022 14.6 0.0 0.033 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) BatD PF13584.6 CRK27165.1 - 0.068 12.0 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Oxygen tolerance DUF4381 PF14316.6 CRK27165.1 - 0.083 13.1 0.2 0.083 13.1 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Herpes_gE PF02480.16 CRK27165.1 - 0.12 11.1 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Hist_deacetyl PF00850.19 CRK27166.1 - 1e-33 117.1 0.1 5.6e-22 78.6 0.0 2.8 3 0 0 3 3 3 2 Histone deacetylase domain Zn_clus PF00172.18 CRK27166.1 - 4.5e-06 26.7 9.4 9.3e-06 25.7 9.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_61 PF03443.14 CRK27167.1 - 8.9e-53 179.3 0.0 1.6e-52 178.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Abhydrolase_4 PF08386.10 CRK27167.1 - 9.6e-24 83.5 0.1 2.5e-23 82.2 0.1 1.7 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 CRK27167.1 - 2.8e-17 63.2 0.0 5.1e-12 46.0 0.0 2.5 2 1 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CRK27167.1 - 0.017 14.6 0.0 0.68 9.4 0.0 2.5 2 0 0 2 2 2 0 Prolyl oligopeptidase family FAD_binding_4 PF01565.23 CRK27168.1 - 2.8e-16 59.5 5.9 8.3e-16 58.0 4.2 2.5 2 1 0 2 2 2 1 FAD binding domain BBE PF08031.12 CRK27168.1 - 0.0028 17.7 0.1 0.012 15.7 0.2 2.1 2 0 0 2 2 2 1 Berberine and berberine like DUF4440 PF14534.6 CRK27170.1 - 5.2e-10 39.7 0.6 6.5e-10 39.4 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) C2 PF00168.30 CRK27171.1 - 5.4e-11 42.7 0.0 9.3e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 C2 domain RIBIOP_C PF04950.12 CRK27173.1 - 6.8e-10 38.9 0.0 7.8e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal PTH2 PF01981.16 CRK27173.1 - 0.015 15.6 0.0 0.019 15.3 0.0 1.2 1 0 0 1 1 1 0 Peptidyl-tRNA hydrolase PTH2 Alk_phosphatase PF00245.20 CRK27176.1 - 4.5e-57 193.9 0.0 5.8e-57 193.5 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 CRK27176.1 - 6.6e-06 25.7 0.0 1.1e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily FAR1 PF03101.15 CRK27177.1 - 2.4e-06 28.2 0.3 3.9e-06 27.5 0.3 1.3 1 0 0 1 1 1 1 FAR1 DNA-binding domain Matrilin_ccoil PF10393.9 CRK27177.1 - 0.0042 16.9 0.4 0.011 15.6 0.1 1.8 2 0 0 2 2 2 1 Trimeric coiled-coil oligomerisation domain of matrilin XhlA PF10779.9 CRK27177.1 - 0.0085 16.3 0.1 0.025 14.8 0.0 1.7 2 0 0 2 2 2 1 Haemolysin XhlA Sec3_C PF09763.9 CRK27177.1 - 0.0092 14.4 0.1 0.012 14.0 0.1 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 AFT PF08731.11 CRK27177.1 - 0.012 16.0 0.2 0.018 15.4 0.2 1.3 1 0 0 1 1 1 0 Transcription factor AFT Baculo_PEP_C PF04513.12 CRK27177.1 - 0.028 14.4 0.0 0.042 13.9 0.0 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Snapin_Pallidin PF14712.6 CRK27177.1 - 0.029 14.8 0.1 0.059 13.8 0.1 1.5 1 0 0 1 1 1 0 Snapin/Pallidin HSBP1 PF06825.12 CRK27177.1 - 0.031 14.1 2.6 0.19 11.6 0.8 2.7 1 1 1 2 2 2 0 Heat shock factor binding protein 1 DUF1664 PF07889.12 CRK27177.1 - 0.033 14.2 0.0 0.056 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Hemagglutinin PF00509.18 CRK27177.1 - 0.035 12.5 0.0 0.044 12.2 0.0 1.1 1 0 0 1 1 1 0 Haemagglutinin CLZ PF16526.5 CRK27177.1 - 0.038 14.3 0.4 0.2 12.1 0.2 2.0 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF948 PF06103.11 CRK27177.1 - 0.05 13.9 0.0 0.11 12.8 0.0 1.5 2 0 0 2 2 1 0 Bacterial protein of unknown function (DUF948) CCDC154 PF15450.6 CRK27177.1 - 0.097 11.2 0.0 0.12 10.9 0.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 154 Tektin PF03148.14 CRK27177.1 - 0.13 11.0 0.0 0.17 10.6 0.0 1.1 1 0 0 1 1 1 0 Tektin family Exonuc_VII_L PF02601.15 CRK27177.1 - 0.13 11.8 0.1 0.15 11.6 0.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit POTRA_3 PF17287.2 CRK27177.1 - 0.15 11.6 0.4 7.6 6.1 0.2 2.5 2 0 0 2 2 2 0 POTRA domain CbiJ PF02571.14 CRK27178.1 - 0.083 12.4 0.0 0.093 12.2 0.0 1.2 1 0 0 1 1 1 0 Precorrin-6x reductase CbiJ/CobK Spore_III_AB PF09548.10 CRK27178.1 - 0.23 11.6 0.3 0.28 11.3 0.3 1.1 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Ribosomal_L34e PF01199.18 CRK27179.1 - 1.7e-43 146.8 3.7 2.3e-43 146.4 3.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e FhuF_C PF11575.8 CRK27179.1 - 0.36 10.8 4.4 1.7 8.7 0.3 2.5 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain Abhydrolase_6 PF12697.7 CRK27180.1 - 1.1e-15 58.8 3.8 2.1e-15 57.9 3.8 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CRK27180.1 - 2.2e-14 53.3 0.0 1.5e-12 47.3 0.0 2.9 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CRK27180.1 - 2.7e-13 50.2 0.0 7.2e-13 48.8 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold DSPc PF00782.20 CRK27180.1 - 2.5e-09 37.0 0.0 4.8e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Thioesterase PF00975.20 CRK27180.1 - 7.9e-06 26.1 0.0 1.5e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain PTPlike_phytase PF14566.6 CRK27180.1 - 5.5e-05 23.3 0.0 0.0001 22.5 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 CRK27180.1 - 0.011 15.4 0.0 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase LIDHydrolase PF10230.9 CRK27180.1 - 0.02 14.4 0.0 0.038 13.5 0.0 1.4 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase FSH1 PF03959.13 CRK27180.1 - 0.024 14.3 0.0 6.6 6.3 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase (FSH1) PGAP1 PF07819.13 CRK27180.1 - 0.054 13.2 0.0 3.2 7.4 0.0 2.7 3 0 0 3 3 3 0 PGAP1-like protein Abhydrolase_2 PF02230.16 CRK27180.1 - 0.099 12.4 0.0 4.3 7.1 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Lipase_3 PF01764.25 CRK27180.1 - 0.17 11.7 0.1 0.44 10.4 0.0 1.6 1 1 1 2 2 2 0 Lipase (class 3) Polysacc_deac_1 PF01522.21 CRK27181.1 - 3.5e-28 98.0 0.0 6.3e-28 97.2 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 CRK27181.1 - 0.0026 17.0 0.0 0.0045 16.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 Glyco_hydro_18 PF00704.28 CRK27182.1 - 1.3e-60 205.8 0.0 1.5e-60 205.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Lipocalin_9 PF17186.4 CRK27182.1 - 0.028 14.7 0.0 0.056 13.7 0.0 1.5 1 0 0 1 1 1 0 Lipocalin-like domain AA_permease_2 PF13520.6 CRK27183.1 - 4e-54 184.1 45.7 5.2e-54 183.7 45.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CRK27183.1 - 1.6e-17 63.3 39.9 2.1e-17 62.9 39.9 1.0 1 0 0 1 1 1 1 Amino acid permease Goodbye PF17109.5 CRK27183.1 - 0.4 11.1 3.4 0.63 10.5 0.1 2.3 2 0 0 2 2 2 0 fungal STAND N-terminal Goodbye domain Ricin_B_lectin PF00652.22 CRK27184.1 - 1.9e-09 37.8 1.3 0.00047 20.4 0.0 4.2 3 2 2 5 5 5 3 Ricin-type beta-trefoil lectin domain CDtoxinA PF03498.14 CRK27184.1 - 0.19 11.3 0.5 21 4.7 0.1 2.9 2 1 1 3 3 3 0 Cytolethal distending toxin A/C domain CorA PF01544.18 CRK27185.1 - 2.2e-28 99.4 4.2 2.4e-25 89.5 2.1 2.4 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein DUF3177 PF11375.8 CRK27185.1 - 0.034 13.9 1.7 0.059 13.1 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3177) 4HBT PF03061.22 CRK27186.1 - 4.5e-14 52.6 1.2 8.6e-14 51.7 1.2 1.5 1 0 0 1 1 1 1 Thioesterase superfamily Peptidase_S41 PF03572.18 CRK27187.1 - 1.8e-05 24.4 0.0 4.8e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 Peptidase family S41 Inhibitor_I66 PF16850.5 CRK27188.1 - 4.6e-07 29.8 0.0 6.3e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I66 Trypsin PF00089.26 CRK27189.1 - 5.2e-61 206.3 1.6 6.2e-61 206.0 1.6 1.0 1 0 0 1 1 1 1 Trypsin CBM_2 PF00553.19 CRK27191.1 - 0.064 13.6 0.2 0.12 12.7 0.1 1.5 1 1 0 1 1 1 0 Cellulose binding domain Toxin_4 PF00706.17 CRK27191.1 - 0.13 12.7 0.0 0.31 11.5 0.0 1.6 1 0 0 1 1 1 0 Anenome neurotoxin Ubie_methyltran PF01209.18 CRK27192.1 - 8e-25 87.5 0.0 8.6e-25 87.4 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Lipase_GDSL PF00657.22 CRK27195.1 - 1.9e-11 44.4 0.7 5.1e-11 42.9 0.7 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 CRK27195.1 - 1.9e-11 44.7 1.0 3.7e-11 43.7 1.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family CE2_N PF17996.1 CRK27195.1 - 0.1 12.6 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate esterase 2 N-terminal UreE_C PF05194.12 CRK27196.1 - 0.0037 17.7 3.0 0.0083 16.6 3.0 1.5 1 0 0 1 1 1 1 UreE urease accessory protein, C-terminal domain Not3 PF04065.15 CRK27196.1 - 0.0064 16.0 0.0 0.0082 15.6 0.0 1.2 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component UreE_C PF05194.12 CRK27197.1 - 0.0044 17.5 4.4 0.0077 16.7 4.4 1.4 1 0 0 1 1 1 1 UreE urease accessory protein, C-terminal domain Not3 PF04065.15 CRK27197.1 - 0.11 11.9 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component ALO PF04030.14 CRK27198.1 - 2.7e-89 299.4 0.0 4.3e-89 298.8 0.0 1.3 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 CRK27198.1 - 4.1e-28 97.9 0.0 6e-28 97.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Lipase_GDSL_2 PF13472.6 CRK27199.1 - 1.2e-16 61.6 0.0 1.6e-16 61.2 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 CRK27199.1 - 1.2e-05 25.4 0.0 2.3e-05 24.5 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase ThiF PF00899.21 CRK27200.1 - 1.3e-40 139.3 0.0 1.9e-40 138.8 0.0 1.1 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 CRK27200.1 - 0.00015 22.1 0.1 0.00051 20.3 0.1 1.8 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 CRK27200.1 - 0.0024 18.1 0.4 0.034 14.4 0.0 2.8 2 0 0 2 2 2 1 TrkA-N domain NAD_binding_7 PF13241.6 CRK27200.1 - 0.031 14.7 0.0 0.074 13.5 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 CRK27200.1 - 0.033 13.8 0.1 0.059 12.9 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Amidase_6 PF12671.7 CRK27200.1 - 0.058 13.5 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Putative amidase domain Melibiase_2 PF16499.5 CRK27200.1 - 0.11 11.6 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Alpha galactosidase A DUF3433 PF11915.8 CRK27201.1 - 4.6e-29 100.7 5.5 4.6e-29 100.7 5.5 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3433) Oxidored_q3 PF00499.20 CRK27201.1 - 0.23 11.2 5.4 0.11 12.2 0.1 2.7 2 2 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Dcc1 PF09724.9 CRK27203.1 - 0.0003 20.2 9.1 0.082 12.2 1.4 2.3 2 0 0 2 2 2 2 Sister chromatid cohesion protein Dcc1 DNA_pol_D_N PF18018.1 CRK27203.1 - 0.059 13.5 0.0 20 5.3 0.0 2.6 2 0 0 2 2 2 0 DNA polymerase delta subunit OB-fold domain Pax7 PF12360.8 CRK27203.1 - 0.14 12.3 11.0 3.3 8.0 2.0 2.9 2 0 0 2 2 2 0 Paired box protein 7 VASP_tetra PF08776.11 CRK27203.1 - 4.4 6.9 8.3 14 5.4 1.1 2.4 2 0 0 2 2 2 0 VASP tetramerisation domain SAICAR_synt PF01259.18 CRK27204.1 - 6.3e-106 353.6 0.0 7.9e-53 179.6 0.0 2.2 2 0 0 2 2 2 2 SAICAR synthetase G-patch PF01585.23 CRK27204.1 - 1.8e-12 47.0 3.5 4e-12 45.8 3.5 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 CRK27204.1 - 5.9e-07 29.5 2.4 2.5e-06 27.5 2.4 2.1 1 0 0 1 1 1 1 G-patch domain zf-RanBP PF00641.18 CRK27204.1 - 1.1e-05 24.6 1.6 2e-05 23.8 1.6 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others RRM_1 PF00076.22 CRK27204.1 - 0.00016 21.5 0.0 0.019 14.8 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_2 PF12756.7 CRK27204.1 - 0.033 14.5 0.6 0.033 14.5 0.6 1.9 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) RED_N PF07808.13 CRK27204.1 - 0.036 13.7 0.2 0.036 13.7 0.2 1.9 2 0 0 2 2 2 0 RED-like protein N-terminal region zf-C2H2_jaz PF12171.8 CRK27204.1 - 2.4 8.6 4.9 0.44 10.9 0.8 2.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Peptidase_M28 PF04389.17 CRK27205.1 - 9.2e-41 139.7 0.0 1.4e-40 139.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 CRK27205.1 - 2.4e-10 40.3 0.0 8.4e-10 38.5 0.0 2.0 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 CRK27205.1 - 7.4e-06 25.8 0.0 2e-05 24.4 0.0 1.8 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Sugar_tr PF00083.24 CRK27207.1 - 0.00036 19.5 0.1 0.00043 19.3 0.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter TPR_2 PF07719.17 CRK27208.1 - 8.3e-16 56.8 0.1 3.4e-05 23.6 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 CRK27208.1 - 1.1e-12 47.1 0.0 0.072 13.3 0.0 4.1 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 CRK27208.1 - 2.1e-12 46.3 0.1 0.0014 18.4 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 CRK27208.1 - 3.3e-10 39.6 0.1 0.013 15.8 0.2 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 CRK27208.1 - 9.8e-10 38.6 1.0 0.003 17.8 0.8 3.1 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 CRK27208.1 - 3.1e-09 36.9 0.9 0.016 15.9 1.2 3.1 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 CRK27208.1 - 7.4e-09 36.0 4.6 3.2e-06 27.5 6.4 2.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 CRK27208.1 - 2.2e-08 33.7 0.1 0.047 13.4 0.1 3.2 1 1 2 3 3 3 3 TPR repeat TPR_16 PF13432.6 CRK27208.1 - 2e-07 31.5 1.9 0.00052 20.6 0.4 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 CRK27208.1 - 5.5e-05 23.2 0.3 0.0062 16.6 1.6 2.6 2 1 1 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CRK27208.1 - 0.00013 22.1 0.6 0.043 14.0 0.4 2.8 1 1 2 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 CRK27208.1 - 0.00025 21.5 2.2 13 6.7 0.0 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 CRK27208.1 - 0.0012 19.2 0.1 0.26 12.0 1.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 CRK27208.1 - 0.0033 17.4 0.0 0.89 9.7 0.0 3.3 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.6 CRK27208.1 - 0.0046 17.3 2.3 0.061 13.7 2.5 2.0 1 1 1 2 2 2 1 Tetratricopeptide repeat ChAPs PF09295.10 CRK27208.1 - 0.012 14.7 0.1 0.16 11.0 0.1 1.9 1 1 1 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) CNH PF00780.22 CRK27213.1 - 4.6e-66 223.3 0.0 6.6e-66 222.7 0.0 1.2 1 0 0 1 1 1 1 CNH domain Beta-lactamase PF00144.24 CRK27213.1 - 9.5e-39 133.5 0.4 9.5e-39 133.5 0.4 2.0 2 0 0 2 2 2 1 Beta-lactamase RhoGEF PF00621.20 CRK27213.1 - 1.5e-21 77.5 0.0 2.5e-21 76.8 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 CRK27213.1 - 1.4e-05 25.2 0.0 5e-05 23.4 0.0 1.9 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 CRK27213.1 - 0.00031 21.2 0.0 0.0058 17.1 0.0 2.5 2 0 0 2 2 2 1 PH domain SNase PF00565.17 CRK27215.1 - 1.7e-66 221.5 1.0 5.6e-19 68.6 0.0 5.5 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 CRK27215.1 - 9.3e-22 77.3 0.0 1.9e-21 76.4 0.0 1.5 1 0 0 1 1 1 1 Tudor domain SMN PF06003.12 CRK27215.1 - 0.0003 20.1 0.2 0.00054 19.3 0.2 1.4 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) TAL_FSA PF00923.19 CRK27217.1 - 7.5e-93 311.0 1.0 8.9e-93 310.8 1.0 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase C5-epim_C PF06662.13 CRK27217.1 - 0.036 13.6 0.0 0.064 12.7 0.0 1.3 1 0 0 1 1 1 0 D-glucuronyl C5-epimerase C-terminus Cas_VVA1548 PF09652.10 CRK27217.1 - 0.045 14.0 0.1 0.091 13.0 0.1 1.5 1 0 0 1 1 1 0 Putative CRISPR-associated protein (Cas_VVA1548) AbfS_sensor PF18225.1 CRK27222.1 - 0.036 14.0 0.0 15 5.6 0.0 2.5 2 0 0 2 2 2 0 Sensor histidine kinase (AbfS) sensor domain Oxysterol_BP PF01237.18 CRK27227.1 - 5.8e-46 157.0 0.0 2.3e-25 89.2 0.0 4.0 1 1 2 3 3 3 3 Oxysterol-binding protein SnoaL_2 PF12680.7 CRK27228.1 - 0.00089 19.9 0.0 0.0028 18.3 0.0 1.8 1 0 0 1 1 1 1 SnoaL-like domain DUF2358 PF10184.9 CRK27228.1 - 0.13 12.5 0.0 0.28 11.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2358) zf-RING_2 PF13639.6 CRK27230.1 - 1.1e-08 35.2 6.2 1.1e-08 35.2 6.2 2.1 2 0 0 2 2 2 1 Ring finger domain zf-ANAPC11 PF12861.7 CRK27230.1 - 8.9e-05 22.5 1.5 8.9e-05 22.5 1.5 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 CRK27230.1 - 0.00086 19.3 4.0 0.0014 18.6 3.0 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.6 CRK27230.1 - 0.0011 18.7 6.1 0.0011 18.7 6.1 1.9 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain PHD PF00628.29 CRK27230.1 - 0.0027 17.6 7.2 0.0051 16.7 7.2 1.5 1 0 0 1 1 1 1 PHD-finger zf-rbx1 PF12678.7 CRK27230.1 - 0.0047 17.2 5.2 0.0047 17.2 5.2 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain FANCL_C PF11793.8 CRK27230.1 - 0.0067 16.6 7.7 0.0067 16.6 7.7 2.0 2 1 0 2 2 2 1 FANCL C-terminal domain zf-RING_5 PF14634.6 CRK27230.1 - 0.0077 16.2 5.7 0.0077 16.2 5.7 2.1 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_1 PF14446.6 CRK27230.1 - 0.027 14.4 2.6 0.027 14.4 2.6 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-C3HC4_3 PF13920.6 CRK27230.1 - 0.031 14.1 2.9 0.083 12.8 2.9 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) SWIM PF04434.17 CRK27230.1 - 0.055 13.2 0.4 0.12 12.1 0.4 1.6 1 0 0 1 1 1 0 SWIM zinc finger zf-UDP PF14569.6 CRK27230.1 - 0.1 12.7 3.9 0.19 11.8 2.4 2.2 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-C3HC4_4 PF15227.6 CRK27230.1 - 0.23 11.7 5.5 2.5 8.3 5.5 2.4 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Di19 PF05605.12 CRK27230.1 - 0.75 10.1 4.8 8.1 6.8 0.0 3.2 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding RINGv PF12906.7 CRK27230.1 - 2.1 8.5 13.2 0.1 12.7 7.9 1.7 2 0 0 2 2 1 0 RING-variant domain DUF4674 PF15719.5 CRK27230.1 - 2.2 8.3 9.9 6.3 6.8 0.2 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4674) zf-C3HC4_2 PF13923.6 CRK27230.1 - 2.7 7.9 13.5 0.047 13.6 5.5 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) MFS_1 PF07690.16 CRK27232.1 - 6e-32 110.9 31.2 8.2e-32 110.5 31.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Leader_Erm PF08253.11 CRK27234.1 - 1.2 9.6 3.0 1.3 9.4 0.1 2.6 2 0 0 2 2 2 0 Erm Leader peptide PilN PF05137.13 CRK27238.1 - 0.16 12.1 0.7 3.4 7.9 0.1 2.7 2 0 0 2 2 2 0 Fimbrial assembly protein (PilN) WD40 PF00400.32 CRK27255.1 - 3.1e-06 27.8 0.1 0.006 17.4 0.0 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK27255.1 - 0.023 15.0 0.1 0.8 10.0 0.0 2.1 1 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain RVT_2 PF07727.14 CRK27269.1 - 2.1e-31 109.4 0.1 4.1e-31 108.5 0.1 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 CRK27269.1 - 2.5e-08 34.1 0.0 1.1e-07 32.0 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 CRK27269.1 - 1e-07 31.7 0.1 2.4e-07 30.5 0.1 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain RVT_1 PF00078.27 CRK27269.1 - 0.007 15.9 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotran_gag_2 PF14223.6 CRK27269.1 - 0.014 15.0 0.9 0.037 13.7 0.9 1.6 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type PrmA PF06325.13 CRK27269.1 - 0.056 12.8 0.2 0.1 12.0 0.2 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Hpr_kinase_C PF07475.12 CRK27269.1 - 0.087 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain BLI1 PF17324.2 CRK27269.1 - 0.14 12.8 0.6 0.52 11.0 0.6 1.9 1 0 0 1 1 1 0 BLOC-1 interactor 1 APP_E2 PF12925.7 CRK27275.1 - 0.022 14.5 0.8 0.041 13.6 0.8 1.5 1 1 0 1 1 1 0 E2 domain of amyloid precursor protein RVT_1 PF00078.27 CRK27277.1 - 0.00063 19.3 0.0 0.001 18.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Helo_like_N PF17111.5 CRK27279.1 - 1.8e-34 119.0 9.3 2.8e-29 102.0 1.1 3.2 2 1 1 3 3 3 3 Fungal N-terminal domain of STAND proteins SesA PF17107.5 CRK27279.1 - 0.024 14.8 0.5 0.024 14.8 0.5 2.6 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases CorA PF01544.18 CRK27279.1 - 0.045 13.1 0.5 0.11 11.8 0.1 1.8 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein RuvX PF03652.15 CRK27279.1 - 0.095 13.1 0.8 2 8.8 0.5 2.4 1 1 1 2 2 2 0 Holliday junction resolvase RasGAP_C PF03836.15 CRK27279.1 - 2.5 8.3 6.2 1.9 8.6 2.2 2.8 2 1 1 3 3 3 0 RasGAP C-terminus TBCC_N PF16752.5 CRK27279.1 - 6.6 7.2 6.9 25 5.4 0.4 3.8 2 1 1 4 4 4 0 Tubulin-specific chaperone C N-terminal domain APH PF01636.23 CRK27281.1 - 3.9e-07 30.2 0.2 1.9e-06 28.0 0.1 2.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CRK27281.1 - 0.0022 17.6 0.0 0.0064 16.1 0.0 1.8 2 0 0 2 2 2 1 Choline/ethanolamine kinase FAF PF11250.8 CRK27281.1 - 0.086 13.1 0.0 0.25 11.6 0.0 1.8 1 0 0 1 1 1 0 Fantastic Four meristem regulator Glyco_tranf_2_3 PF13641.6 CRK27285.1 - 1.4e-13 51.2 0.1 2.1e-13 50.7 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 CRK27285.1 - 3.8e-05 23.2 0.3 0.00012 21.6 0.3 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 21 DUF2695 PF10905.8 CRK27288.1 - 0.071 13.3 0.0 0.21 11.8 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2695) Pkinase PF00069.25 CRK27290.1 - 6.3e-13 48.7 0.0 1e-12 48.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 CRK27290.1 - 1.3e-12 47.2 0.1 1.2e-11 44.1 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Pkinase_Tyr PF07714.17 CRK27290.1 - 0.0064 15.8 0.0 0.0097 15.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase HDV_ag PF01517.18 CRK27295.1 - 0.067 13.0 0.3 0.14 11.9 0.3 1.5 1 0 0 1 1 1 0 Hepatitis delta virus delta antigen Ank_2 PF12796.7 CRK27297.1 - 7.7e-59 196.3 18.7 9.9e-16 58.1 2.0 4.9 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CRK27297.1 - 3.9e-45 151.7 13.6 1.5e-08 35.0 0.0 6.4 3 3 4 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 CRK27297.1 - 1.6e-34 116.8 24.2 2.8e-06 27.5 0.1 9.4 8 1 0 8 8 8 6 Ankyrin repeat Ank_3 PF13606.6 CRK27297.1 - 3.1e-32 107.0 11.7 2.9e-06 27.2 0.0 9.7 9 1 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.6 CRK27297.1 - 6.4e-32 109.2 16.9 8.2e-08 32.4 0.0 8.6 4 3 5 9 9 9 7 Ankyrin repeats (many copies) Pirin_C_2 PF17954.1 CRK27297.1 - 0.00038 20.6 1.7 0.96 9.7 0.1 2.6 2 0 0 2 2 2 2 Quercetinase C-terminal cupin domain Ribosomal_L22e PF01776.17 CRK27316.1 - 1e-24 87.0 0.1 1.1e-24 86.9 0.1 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Pyr_redox_2 PF07992.14 CRK27324.1 - 5.9e-15 55.3 0.0 6.9e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FA_desaturase PF00487.24 CRK27324.1 - 4e-14 53.1 0.3 4.8e-14 52.8 0.3 1.2 1 0 0 1 1 1 1 Fatty acid desaturase GIDA PF01134.22 CRK27324.1 - 1.1e-09 37.9 0.2 1.3e-09 37.6 0.2 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 CRK27324.1 - 1.7e-09 37.6 0.1 2e-09 37.3 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CRK27324.1 - 1e-07 31.4 2.7 1.7e-07 30.7 2.3 1.4 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 CRK27324.1 - 2e-07 31.1 0.2 3.6e-07 30.3 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 CRK27324.1 - 1.3e-05 24.1 1.9 1.7e-05 23.7 1.9 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 CRK27324.1 - 0.00061 19.1 0.2 0.00081 18.7 0.2 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 CRK27324.1 - 0.00088 18.9 0.5 0.0012 18.6 0.5 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 CRK27324.1 - 0.006 15.9 1.3 0.01 15.1 1.3 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 CRK27324.1 - 0.012 14.7 0.1 0.019 14.0 0.1 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.27 CRK27324.1 - 0.012 16.1 0.9 0.023 15.3 0.9 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 CRK27324.1 - 0.048 12.5 0.7 0.067 12.0 0.7 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FAD_binding_3 PF01494.19 CRK27324.1 - 0.061 12.6 1.4 0.094 11.9 1.4 1.2 1 0 0 1 1 1 0 FAD binding domain FMO-like PF00743.19 CRK27324.1 - 0.12 10.8 0.3 0.16 10.3 0.3 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 CRK27324.1 - 0.75 9.0 3.1 1.1 8.5 3.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Vac14_Fig4_bd PF11916.8 CRK27328.1 - 1.2e-81 272.7 8.3 2.8e-81 271.4 8.3 1.7 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 CRK27328.1 - 3e-41 139.9 0.3 1.2e-37 128.4 0.1 4.0 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 CRK27328.1 - 1.4e-08 35.0 7.5 0.002 18.6 0.1 4.9 5 0 0 5 5 5 3 HEAT-like repeat HEAT PF02985.22 CRK27328.1 - 4.4e-08 32.7 2.8 0.00064 19.8 0.0 5.3 5 0 0 5 5 5 1 HEAT repeat Cnd1 PF12717.7 CRK27328.1 - 5.4e-07 29.8 2.0 0.0081 16.2 0.3 3.5 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CRK27328.1 - 0.00037 20.8 1.7 3.5 8.1 0.0 5.0 4 1 0 4 4 4 1 HEAT repeats Arm PF00514.23 CRK27328.1 - 0.00081 19.3 0.1 0.51 10.5 0.0 4.6 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Mito_carr PF00153.27 CRK27331.1 - 1.7e-66 220.2 6.9 9.7e-23 79.9 0.4 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CRK27331.1 - 0.0052 16.0 5.1 0.52 9.4 0.3 3.2 1 1 3 4 4 4 2 Gammaproteobacterial serine protease COG6 PF06419.11 CRK27333.1 - 9.4e-212 704.6 4.1 1.1e-211 704.4 4.1 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 Forkhead PF00250.18 CRK27333.1 - 0.059 13.6 0.1 0.13 12.5 0.1 1.5 1 0 0 1 1 1 0 Forkhead domain COG2 PF06148.11 CRK27333.1 - 0.068 13.3 1.1 0.43 10.7 0.1 2.8 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 NAPRTase_N PF17767.1 CRK27333.1 - 0.07 13.5 0.1 2.9 8.3 0.0 3.0 2 1 0 2 2 2 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain CofC PF01983.16 CRK27333.1 - 0.15 11.2 0.0 0.41 9.8 0.0 1.7 1 0 0 1 1 1 0 Guanylyl transferase CofC like Ribosomal_S17 PF00366.20 CRK27335.1 - 2.1e-23 82.2 1.8 2.1e-23 82.2 1.8 1.7 2 0 0 2 2 2 1 Ribosomal protein S17 RelB PF04221.12 CRK27335.1 - 0.063 13.3 0.1 0.14 12.2 0.0 1.6 2 0 0 2 2 2 0 RelB antitoxin EMG1 PF03587.14 CRK27337.1 - 6.4e-69 231.5 1.0 6.9e-68 228.1 1.0 1.9 1 1 0 1 1 1 1 EMG1/NEP1 methyltransferase Cys_Met_Meta_PP PF01053.20 CRK27340.1 - 7.8e-33 113.5 0.0 1.1e-32 113.0 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 CRK27340.1 - 0.086 12.0 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II SPX PF03105.19 CRK27342.1 - 5.7e-65 220.7 0.1 7e-65 220.4 0.1 1.1 1 0 0 1 1 1 1 SPX domain zf-C3HC4_3 PF13920.6 CRK27342.1 - 2.6 8.0 4.3 7.4 6.5 4.3 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DnaJ PF00226.31 CRK27344.1 - 1.9e-24 85.6 0.9 1.9e-24 85.6 0.9 2.2 3 0 0 3 3 3 1 DnaJ domain zf-C2H2_jaz PF12171.8 CRK27344.1 - 4.1e-10 39.7 3.9 8.1e-10 38.7 3.9 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CRK27344.1 - 2e-08 34.3 1.0 4.4e-08 33.3 1.0 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 CRK27344.1 - 0.00013 22.2 0.6 0.0003 21.1 0.6 1.6 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) RPT PF13446.6 CRK27344.1 - 0.011 15.7 0.1 0.062 13.2 0.1 2.3 1 1 0 1 1 1 0 A repeated domain in UCH-protein zf-C2H2_4 PF13894.6 CRK27344.1 - 0.04 14.8 0.2 0.11 13.4 0.2 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CRK27344.1 - 0.061 13.3 1.3 0.12 12.4 1.3 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 CRK27344.1 - 0.14 12.6 0.4 0.38 11.3 0.4 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type Peptidase_C54 PF03416.19 CRK27346.1 - 5.4e-93 311.4 0.0 8.2e-93 310.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family C54 R3H PF01424.22 CRK27348.1 - 3.7e-16 58.9 0.1 1.3e-15 57.1 0.0 2.0 2 0 0 2 2 2 1 R3H domain G-patch PF01585.23 CRK27348.1 - 8.3e-10 38.4 3.7 2.3e-09 37.0 3.7 1.8 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 CRK27348.1 - 0.00031 20.8 2.8 0.0012 18.9 2.8 2.1 1 0 0 1 1 1 1 G-patch domain Kinesin_assoc PF16183.5 CRK27348.1 - 0.02 15.0 0.8 0.17 12.0 0.0 2.6 3 0 0 3 3 3 0 Kinesin-associated Histone PF00125.24 CRK27350.1 - 5.1e-22 78.6 2.1 6.3e-22 78.3 2.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CRK27350.1 - 4.2e-05 23.7 0.0 0.0001 22.5 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 CRK27350.1 - 0.00025 21.5 0.0 0.00043 20.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.13 CRK27350.1 - 0.037 13.7 0.1 0.091 12.4 0.1 1.6 1 1 0 1 1 1 0 Replication protein C N-terminal domain Histone_H2A_C PF16211.5 CRK27351.1 - 4.3e-21 74.3 2.9 7.6e-21 73.6 2.9 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 CRK27351.1 - 6.8e-17 62.1 0.0 9.3e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CRK27351.1 - 1e-05 25.7 0.0 1.4e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Complex1_LYR PF05347.15 CRK27352.1 - 1e-09 38.3 2.9 1.3e-09 37.9 2.9 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DUF647 PF04884.14 CRK27355.1 - 5.3e-86 288.2 1.1 5.3e-86 288.2 1.1 2.0 2 0 0 2 2 2 1 Vitamin B6 photo-protection and homoeostasis MDD_C PF18376.1 CRK27355.1 - 3e-62 209.7 0.0 4.7e-62 209.0 0.0 1.3 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain AA_permease_2 PF13520.6 CRK27355.1 - 1.3e-51 175.8 30.8 1.3e-51 175.8 30.8 1.9 2 0 0 2 2 2 1 Amino acid permease AA_permease PF00324.21 CRK27355.1 - 2.6e-25 89.0 26.2 8e-25 87.4 26.2 1.8 1 0 0 1 1 1 1 Amino acid permease GHMP_kinases_N PF00288.26 CRK27355.1 - 5.1e-08 33.0 0.5 5.1e-08 33.0 0.5 3.1 3 0 0 3 3 3 1 GHMP kinases N terminal domain S36_mt PF10937.8 CRK27356.1 - 1.3e-40 139.6 1.8 1.5e-40 139.3 1.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S36, mitochondrial PHO4 PF01384.20 CRK27358.1 - 5.2e-110 367.6 11.2 6.7e-110 367.3 11.2 1.1 1 0 0 1 1 1 1 Phosphate transporter family CLN3 PF02487.17 CRK27359.1 - 3e-161 536.9 2.0 3.5e-161 536.7 2.0 1.0 1 0 0 1 1 1 1 CLN3 protein MFS_1 PF07690.16 CRK27359.1 - 7.7e-05 21.8 28.8 0.0015 17.5 10.3 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Trypsin_2 PF13365.6 CRK27360.1 - 2e-09 38.5 0.0 8.4e-09 36.5 0.0 2.1 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 CRK27360.1 - 3.2e-06 27.1 0.0 1.1e-05 25.4 0.0 1.8 1 1 0 1 1 1 1 Trypsin Amidohydro_3 PF07969.11 CRK27361.1 - 9e-57 193.6 3.7 1.2e-56 193.2 3.7 1.1 1 0 0 1 1 1 1 Amidohydrolase family Cutinase PF01083.22 CRK27361.1 - 7.7e-36 123.7 2.5 1.2e-35 123.0 2.5 1.3 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 CRK27361.1 - 0.00084 19.0 0.2 0.0015 18.1 0.2 1.4 1 0 0 1 1 1 1 PE-PPE domain Amidohydro_1 PF01979.20 CRK27361.1 - 0.001 18.5 0.1 0.67 9.2 0.0 2.4 2 1 0 2 2 2 2 Amidohydrolase family Abhydrolase_3 PF07859.13 CRK27361.1 - 0.08 12.8 1.3 0.46 10.3 0.3 2.3 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 CRK27361.1 - 0.12 12.2 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Transp_cyt_pur PF02133.15 CRK27362.1 - 4.1e-75 253.2 40.5 4.7e-75 253.1 40.5 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF917 PF06032.12 CRK27363.1 - 3.5e-105 351.7 1.3 9.1e-105 350.3 0.8 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.18 CRK27363.1 - 3.1e-26 92.3 10.6 3.2e-21 75.8 0.9 3.4 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 CRK27363.1 - 3.3e-22 79.0 4.1 4.6e-20 72.1 0.0 4.0 5 1 0 5 5 5 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.6 CRK27363.1 - 4.4e-05 22.3 3.1 0.054 12.1 0.3 3.1 3 0 0 3 3 3 2 MutL protein StbA PF06406.11 CRK27363.1 - 0.071 12.3 0.9 9 5.4 0.0 2.6 3 0 0 3 3 3 0 StbA protein Fungal_trans_2 PF11951.8 CRK27365.1 - 5.5e-20 71.5 0.9 1.3e-19 70.2 0.8 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK27365.1 - 6e-07 29.5 8.4 1.2e-06 28.6 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RibD_C PF01872.17 CRK27367.1 - 2.3e-18 66.8 0.0 5e-17 62.4 0.0 2.0 1 1 0 1 1 1 1 RibD C-terminal domain DHFR_1 PF00186.19 CRK27367.1 - 0.00029 20.6 0.0 0.00032 20.4 0.0 1.2 1 0 0 1 1 1 1 Dihydrofolate reductase NAD_binding_10 PF13460.6 CRK27368.1 - 2.5e-09 37.3 0.1 5.4e-09 36.2 0.1 1.6 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 CRK27368.1 - 7.7e-06 25.6 0.0 3.3e-05 23.6 0.0 1.8 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 CRK27368.1 - 0.00092 18.7 0.6 0.33 10.4 0.0 3.3 2 1 0 3 3 3 2 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 CRK27368.1 - 0.02 14.3 0.0 0.084 12.2 0.0 2.0 2 1 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HRDC PF00570.23 CRK27368.1 - 0.19 11.8 0.4 13 5.9 0.0 3.1 4 0 0 4 4 4 0 HRDC domain AMP-binding PF00501.28 CRK27370.1 - 1.8e-44 152.0 0.1 2e-44 151.9 0.1 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Crystall PF00030.19 CRK27373.1 - 0.00026 21.1 0.1 0.00037 20.6 0.1 1.4 1 1 0 1 1 1 1 Beta/Gamma crystallin Aldo_ket_red PF00248.21 CRK27375.1 - 8.8e-18 64.5 0.0 1.2e-17 64.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF4811 PF16069.5 CRK27387.1 - 0.04 13.8 0.6 0.046 13.6 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4811) CPSase_L_D2 PF02786.17 CRK27390.1 - 1.2e-25 90.3 0.0 1.4e-25 90.0 0.0 1.1 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_Ter PF15632.6 CRK27390.1 - 0.013 15.3 0.0 0.015 15.1 0.0 1.1 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.13 CRK27390.1 - 0.074 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus tRNA_SAD PF07973.14 CRK27391.1 - 1.6e-11 44.1 0.1 2.3e-11 43.6 0.1 1.3 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DUF1816 PF08846.10 CRK27391.1 - 0.15 12.1 0.1 0.43 10.6 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1816) p450 PF00067.22 CRK27392.1 - 0.00063 18.6 0.0 0.00069 18.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RNA_pol_Rpc34 PF05158.12 CRK27393.1 - 1.9e-64 218.2 0.0 2.2e-64 218.0 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit Ribosomal_S25 PF03297.15 CRK27393.1 - 0.16 12.2 0.0 0.3 11.3 0.0 1.4 1 0 0 1 1 1 0 S25 ribosomal protein MARVEL PF01284.23 CRK27394.1 - 0.0017 18.4 15.9 0.0055 16.7 15.2 1.8 1 1 0 1 1 1 1 Membrane-associating domain Fungal_trans_2 PF11951.8 CRK27395.1 - 6.4e-65 219.4 0.5 1.1e-64 218.7 0.5 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK27395.1 - 1.2e-07 31.7 7.3 2.6e-07 30.6 7.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NRBF2 PF08961.10 CRK27396.1 - 0.82 9.2 3.4 0.73 9.4 0.3 2.0 2 0 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator FAD_binding_7 PF03441.14 CRK27397.1 - 2.2e-82 275.4 1.1 2.4e-82 275.3 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 CRK27397.1 - 1.4e-41 142.3 0.0 2.3e-41 141.5 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase Forkhead PF00250.18 CRK27398.1 - 1.1e-14 54.5 0.2 2.7e-14 53.2 0.1 1.8 2 0 0 2 2 2 1 Forkhead domain XLF PF09302.11 CRK27399.1 - 2.2e-50 171.3 0.0 4.4e-50 170.3 0.0 1.5 1 0 0 1 1 1 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component Ribosomal_L14 PF00238.19 CRK27400.1 - 3e-31 108.0 0.0 4.9e-31 107.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e FAD_binding_4 PF01565.23 CRK27400.1 - 4.4e-29 101.0 0.9 7.3e-29 100.3 0.9 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 CRK27400.1 - 2.3e-09 37.2 0.0 4.6e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like DUF5427 PF10310.9 CRK27403.1 - 7.9e-178 592.2 0.0 9.3e-178 591.9 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5427) Flu_M1_C PF08289.11 CRK27403.1 - 0.051 13.8 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain Ndc1_Nup PF09531.10 CRK27403.1 - 0.81 8.3 4.1 1 7.9 4.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Malic_M PF03949.15 CRK27404.1 - 1.2e-85 286.9 0.1 1.6e-85 286.5 0.1 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 CRK27404.1 - 6.1e-65 218.4 0.0 8.9e-65 217.9 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain MFS_1 PF07690.16 CRK27405.1 - 1.7e-12 47.0 54.8 2.4e-10 39.9 29.7 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CRK27405.1 - 4.1e-09 35.4 18.1 7.3e-09 34.6 18.1 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Glyco_hydro_3_C PF01915.22 CRK27406.1 - 2.3e-38 132.2 0.0 4.3e-38 131.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 CRK27406.1 - 2e-24 86.6 0.0 3.4e-23 82.5 0.0 2.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 CRK27406.1 - 7.6e-23 80.4 0.1 1.2e-22 79.7 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Methyltransf_11 PF08241.12 CRK27408.1 - 3.7e-06 27.5 0.0 5.9e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK27408.1 - 0.001 19.7 0.0 0.0025 18.5 0.0 1.7 2 1 0 2 2 2 1 Methyltransferase domain CRC_subunit PF08624.10 CRK27409.1 - 5.6e-43 146.6 0.0 6.7e-43 146.4 0.0 1.1 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit ANAPC4_WD40 PF12894.7 CRK27410.1 - 6e-16 58.5 5.8 8.8e-06 25.9 0.2 3.3 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CRK27410.1 - 8.9e-12 45.3 17.1 0.00012 22.8 0.1 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.11 CRK27410.1 - 1.3e-05 25.2 0.3 0.0046 16.9 0.0 2.4 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A IF-2B PF01008.17 CRK27411.1 - 1.3e-75 254.2 1.0 1.5e-75 254.0 1.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family DUF1786 PF08735.10 CRK27411.1 - 0.056 12.7 0.2 3.3 6.9 0.0 2.6 3 0 0 3 3 3 0 Putative pyruvate format-lyase activating enzyme (DUF1786) DUF3533 PF12051.8 CRK27413.1 - 3.9e-116 388.1 14.9 4.8e-116 387.8 14.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) DUF4714 PF15833.5 CRK27413.1 - 0.5 10.3 2.0 0.99 9.4 2.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4714) GWT1 PF06423.12 CRK27413.1 - 7.7 6.6 6.3 1.7 8.8 0.1 2.7 3 0 0 3 3 3 0 GWT1 ADH_N PF08240.12 CRK27414.1 - 0.0002 21.2 0.1 0.0014 18.5 0.1 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain DUF4129 PF13559.6 CRK27414.1 - 0.14 12.5 1.6 17 5.8 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4129) NDUF_B8 PF05821.11 CRK27415.1 - 1.4e-09 38.0 0.2 2.1e-09 37.5 0.2 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) SNF2_N PF00176.23 CRK27416.1 - 3e-42 144.6 0.2 5.8e-42 143.7 0.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CRK27416.1 - 1.1e-05 25.8 0.1 2.2e-05 24.8 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HSA PF07529.13 CRK27416.1 - 5.5e-05 23.4 11.2 0.00026 21.2 11.0 2.4 1 1 0 1 1 1 1 HSA ResIII PF04851.15 CRK27416.1 - 0.0048 16.9 0.0 0.011 15.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 CRK27416.1 - 0.098 11.8 0.1 2.1 7.5 0.0 2.4 2 0 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 DEAD_2 PF06733.15 CRK27416.1 - 0.16 11.6 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 DEAD_2 Pribosyltran_N PF13793.6 CRK27417.1 - 6.1e-37 126.1 0.1 1.5e-36 124.9 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 CRK27417.1 - 6.8e-33 114.2 6.2 5.6e-26 91.7 1.7 3.6 3 1 1 4 4 4 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 CRK27417.1 - 2.7e-16 59.5 1.5 3.4e-16 59.2 0.6 1.6 2 0 0 2 2 2 1 Phosphoribosyl transferase domain HsbA PF12296.8 CRK27418.1 - 2.3e-26 92.5 20.3 2.3e-26 92.5 20.3 2.1 2 0 0 2 2 2 1 Hydrophobic surface binding protein A T3SS_TC PF06511.11 CRK27418.1 - 0.14 11.5 4.7 0.19 11.1 4.7 1.1 1 0 0 1 1 1 0 Type III secretion systems tip complex components DUF1664 PF07889.12 CRK27418.1 - 0.32 11.0 1.8 3.9 7.5 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CorA PF01544.18 CRK27420.1 - 3.4e-05 23.3 0.7 8.7e-05 22.0 0.2 1.8 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein LapA_dom PF06305.11 CRK27420.1 - 0.072 12.9 0.5 2.7 7.9 0.0 2.6 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain E1-E2_ATPase PF00122.20 CRK27422.1 - 1e-18 67.5 7.6 2e-10 40.5 0.0 2.5 2 0 0 2 2 2 2 E1-E2 ATPase Hydrolase PF00702.26 CRK27422.1 - 5.7e-18 66.0 0.1 2.1e-16 60.8 0.1 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CRK27422.1 - 1.8e-14 53.6 0.1 4e-14 52.5 0.1 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CRK27422.1 - 1e-07 32.0 1.8 1.2e-05 25.2 0.5 2.6 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CRK27422.1 - 9.1e-07 28.5 0.1 2.2e-06 27.2 0.1 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus RPE65 PF03055.15 CRK27423.1 - 1.6e-39 136.4 0.0 1.8e-39 136.2 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein DUF2205 PF10224.9 CRK27424.1 - 8e-34 115.5 0.3 1.3e-33 114.8 0.3 1.3 1 0 0 1 1 1 1 Short coiled-coil protein AAA_32 PF13654.6 CRK27424.1 - 0.11 11.3 0.1 0.14 10.9 0.1 1.1 1 0 0 1 1 1 0 AAA domain IMUP PF15761.5 CRK27424.1 - 0.14 12.9 2.6 0.25 12.1 2.6 1.3 1 0 0 1 1 1 0 Immortalisation up-regulated protein Dehydrin PF00257.19 CRK27424.1 - 0.26 11.8 1.8 0.45 11.1 1.8 1.3 1 0 0 1 1 1 0 Dehydrin DUF4006 PF13179.6 CRK27426.1 - 0.0072 16.2 0.0 0.0089 15.9 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF4006) CD34_antigen PF06365.12 CRK27426.1 - 0.012 15.2 0.0 0.014 15.0 0.0 1.0 1 0 0 1 1 1 0 CD34/Podocalyxin family EphA2_TM PF14575.6 CRK27426.1 - 0.012 16.5 0.0 0.015 16.2 0.0 1.1 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Protocadherin PF08374.11 CRK27426.1 - 0.035 14.1 0.0 0.038 14.0 0.0 1.1 1 0 0 1 1 1 0 Protocadherin DUF3169 PF11368.8 CRK27426.1 - 0.065 12.7 0.0 0.076 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) NicO PF03824.16 CRK27426.1 - 0.099 12.0 0.0 0.11 11.8 0.0 1.0 1 0 0 1 1 1 0 High-affinity nickel-transport protein Sugar_tr PF00083.24 CRK27427.1 - 3.7e-55 187.6 0.4 4.6e-55 187.3 0.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK27427.1 - 1.1e-07 31.1 2.0 1.2e-07 31.1 2.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 CRK27427.1 - 0.00014 20.6 2.1 0.00019 20.2 2.1 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein STAG PF08514.11 CRK27428.1 - 0.019 14.9 0.2 0.082 12.8 0.2 1.8 1 1 1 2 2 2 0 STAG domain Zw10 PF06248.13 CRK27428.1 - 0.13 10.8 0.0 0.18 10.3 0.0 1.1 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 VPS28 PF03997.12 CRK27428.1 - 0.28 10.8 2.5 0.3 10.7 0.9 1.8 1 1 1 2 2 2 0 VPS28 protein ATG16 PF08614.11 CRK27428.1 - 0.35 11.1 4.3 0.7 10.1 4.2 1.6 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) PAS_9 PF13426.7 CRK27429.1 - 6.1e-14 52.1 0.0 3.3e-13 49.8 0.0 2.1 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 CRK27429.1 - 0.0056 16.7 0.0 0.053 13.5 0.0 2.3 2 0 0 2 2 2 1 PAS fold WD40 PF00400.32 CRK27430.1 - 1.2e-13 51.3 10.4 0.00031 21.5 0.1 4.6 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK27430.1 - 6.1e-10 39.3 4.2 2.8e-05 24.3 0.5 2.9 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CRK27430.1 - 0.038 13.9 0.0 1.4 8.8 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A tRNA_anti-like PF12869.7 CRK27430.1 - 0.11 12.1 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 tRNA_anti-like WD40 PF00400.32 CRK27431.1 - 7.5e-06 26.6 0.0 9.5e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 WD domain, G-beta repeat Ge1_WD40 PF16529.5 CRK27431.1 - 0.16 10.9 0.0 0.17 10.8 0.0 1.0 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Hydrolase_4 PF12146.8 CRK27432.1 - 3.4e-51 173.8 0.0 4.2e-51 173.5 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CRK27432.1 - 2.8e-16 60.8 3.0 3.4e-16 60.5 3.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CRK27432.1 - 2.6e-13 50.2 0.1 1.2e-11 44.7 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold ABC_membrane PF00664.23 CRK27433.1 - 4.3e-44 151.2 1.9 5.9e-44 150.8 1.9 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region CTD_bind PF04818.13 CRK27433.1 - 6.9e-17 62.0 0.0 1.8e-16 60.7 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CREPT PF16566.5 CRK27433.1 - 0.0026 17.9 1.5 0.005 17.0 0.5 2.0 2 0 0 2 2 2 1 Cell-cycle alteration and expression-elevated protein in tumour Clathrin_lg_ch PF01086.17 CRK27434.1 - 2e-79 266.9 8.6 2.3e-79 266.7 8.6 1.0 1 0 0 1 1 1 1 Clathrin light chain Lipoprotein_8 PF02030.15 CRK27434.1 - 0.032 13.0 1.8 0.039 12.7 1.8 1.1 1 0 0 1 1 1 0 Hypothetical lipoprotein (MG045 family) Serglycin PF04360.12 CRK27434.1 - 5.9 6.8 8.9 2 8.3 0.3 3.1 3 1 1 4 4 4 0 Serglycin COX7a PF02238.15 CRK27435.1 - 1.9e-18 66.6 0.6 3.5e-18 65.7 0.6 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII Syntaxin_2 PF14523.6 CRK27435.1 - 0.15 12.4 0.6 0.26 11.7 0.6 1.3 1 0 0 1 1 1 0 Syntaxin-like protein EF-hand_1 PF00036.32 CRK27436.1 - 1.1e-41 137.3 12.9 7.8e-10 37.6 0.9 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CRK27436.1 - 3.5e-36 123.5 5.8 3.9e-19 68.9 2.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CRK27436.1 - 6.8e-35 118.7 11.4 2.3e-15 56.1 0.6 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 CRK27436.1 - 2.1e-30 102.0 9.5 1.9e-09 36.7 0.2 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CRK27436.1 - 6.5e-26 88.6 10.6 2.6e-06 26.7 0.3 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 CRK27436.1 - 1.5e-16 60.5 0.4 2.3e-09 37.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 CRK27436.1 - 3.4e-09 36.6 1.9 0.00075 19.4 0.2 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CRK27436.1 - 5.6e-09 36.3 0.2 0.0016 18.7 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 CRK27436.1 - 9.9e-07 28.7 0.0 0.0077 16.2 0.0 3.0 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 CRK27436.1 - 5.8e-06 26.3 1.6 2.3e-05 24.4 0.2 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_11 PF08976.11 CRK27436.1 - 9.1e-05 23.3 0.2 0.0022 18.8 0.1 2.0 1 1 1 2 2 2 1 EF-hand domain TerB PF05099.13 CRK27436.1 - 0.00012 22.0 0.3 0.35 10.8 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.13 CRK27436.1 - 0.00045 20.2 1.8 0.44 10.5 0.0 3.5 1 1 3 4 4 4 1 Caleosin related protein RNA_pol_Rpb4 PF03874.16 CRK27436.1 - 0.00062 20.1 0.8 0.66 10.3 0.1 2.7 2 1 1 3 3 3 2 RNA polymerase Rpb4 DUF3349 PF11829.8 CRK27436.1 - 0.0014 19.3 0.4 3.7 8.4 0.0 2.9 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) Dockerin_1 PF00404.18 CRK27436.1 - 0.0053 16.9 7.0 0.38 11.0 0.8 2.9 1 1 2 3 3 3 2 Dockerin type I domain DUF5580 PF17743.1 CRK27436.1 - 0.006 15.2 0.0 0.0062 15.1 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) SurA_N_2 PF13623.6 CRK27436.1 - 0.0091 15.9 0.9 0.32 10.9 0.1 2.2 1 1 1 2 2 2 1 SurA N-terminal domain EF-hand_14 PF17959.1 CRK27436.1 - 0.012 16.0 0.5 6.2 7.2 0.1 2.4 1 1 1 2 2 2 0 EF-hand domain Poly_export PF02563.16 CRK27436.1 - 0.023 14.9 0.0 0.18 12.1 0.0 2.5 2 1 0 2 2 2 0 Polysaccharide biosynthesis/export protein DUF4497 PF14924.6 CRK27436.1 - 0.036 14.5 0.0 8.7 6.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4497) RuvA_C PF07499.13 CRK27436.1 - 0.058 13.9 0.1 8.5 6.9 0.0 3.0 3 0 0 3 3 3 0 RuvA, C-terminal domain MotA_activ PF09114.10 CRK27436.1 - 0.061 13.4 0.3 1.2 9.3 0.0 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain dCache_2 PF08269.11 CRK27436.1 - 0.066 12.4 0.1 1.1 8.4 0.1 2.1 1 1 1 2 2 2 0 Cache domain DUF5132 PF17195.4 CRK27436.1 - 0.15 12.2 0.5 21 5.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF5132) RloB PF13707.6 CRK27436.1 - 0.16 12.2 1.1 0.76 9.9 0.2 2.0 1 1 1 2 2 2 0 RloB-like protein Adaptin_N PF01602.20 CRK27437.1 - 3.2e-120 402.2 0.9 8e-113 377.8 0.0 2.1 1 1 1 2 2 2 2 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 CRK27437.1 - 6e-22 78.1 0.0 1.6e-21 76.7 0.0 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 CRK27437.1 - 2.4e-09 37.4 4.9 1e-05 25.7 0.0 3.9 2 2 2 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CRK27437.1 - 0.00052 20.3 4.2 1.8 9.0 0.1 4.5 4 2 1 5 5 5 2 HEAT repeats DUF3730 PF12530.8 CRK27437.1 - 0.001 18.7 0.4 0.072 12.7 0.2 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF3730) HEAT_EZ PF13513.6 CRK27437.1 - 0.04 14.4 1.6 34 5.1 0.0 4.8 6 0 0 6 6 6 0 HEAT-like repeat HEAT PF02985.22 CRK27437.1 - 0.044 14.1 3.8 5.7 7.5 0.1 4.2 4 0 0 4 4 4 0 HEAT repeat Cohesin_HEAT PF12765.7 CRK27437.1 - 0.16 12.3 0.8 0.49 10.8 0.2 2.3 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion Ndufs5 PF10200.9 CRK27440.1 - 0.00083 19.6 0.0 0.00093 19.4 0.0 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3128 PF11326.8 CRK27440.1 - 0.03 14.7 1.3 0.15 12.4 1.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) COX6B PF02297.17 CRK27440.1 - 0.066 13.5 0.3 0.095 12.9 0.3 1.3 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb CHCH PF06747.13 CRK27440.1 - 0.11 12.6 0.6 0.21 11.8 0.6 1.5 1 0 0 1 1 1 0 CHCH domain Sec39 PF08314.11 CRK27441.1 - 3.6e-283 941.6 0.7 4.2e-283 941.4 0.7 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 Glyco_transf_8 PF01501.20 CRK27443.1 - 2.3e-22 79.8 0.5 5.5e-21 75.3 0.5 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 CRK27443.1 - 0.066 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Mannosyltransferase putative CMD PF02627.20 CRK27445.1 - 0.001 19.1 0.4 0.0082 16.2 0.0 2.2 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family Sec39 PF08314.11 CRK27446.1 - 3e-281 935.3 0.3 3.5e-281 935.1 0.3 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 RITA PF17066.5 CRK27447.1 - 0.14 11.7 0.7 0.14 11.7 0.7 1.2 1 1 0 1 1 1 0 RBPJ-interacting and tubulin associated protein Chitin_synth_2 PF03142.15 CRK27448.1 - 3.6e-37 128.2 0.3 3.9e-37 128.1 0.3 1.0 1 0 0 1 1 1 1 Chitin synthase SpoVAE PF14097.6 CRK27448.1 - 0.05 13.3 0.0 0.055 13.1 0.0 1.2 1 0 0 1 1 1 0 Stage V sporulation protein AE1 Fungal_trans PF04082.18 CRK27449.1 - 1.2e-09 37.6 0.3 2.2e-09 36.7 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain GCP_N_terminal PF17681.1 CRK27449.1 - 0.006 16.2 0.1 0.0083 15.8 0.1 1.2 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal DUF4693 PF15764.5 CRK27449.1 - 0.06 12.9 0.1 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4693) Sugar_tr PF00083.24 CRK27450.1 - 1.3e-77 261.6 21.9 1.5e-77 261.4 21.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK27450.1 - 6.9e-15 54.8 25.6 6.9e-15 54.8 25.6 2.1 1 1 2 3 3 3 1 Major Facilitator Superfamily MFS_1_like PF12832.7 CRK27450.1 - 9.7e-05 21.4 1.6 9.7e-05 21.4 1.6 2.4 2 1 1 3 3 3 1 MFS_1 like family TPR_19 PF14559.6 CRK27450.1 - 0.063 13.8 0.0 0.13 12.8 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Glyco_hydro_2_C PF02836.17 CRK27451.1 - 2e-102 342.4 0.1 2.9e-102 341.9 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 CRK27451.1 - 1.2e-39 135.9 0.1 2.4e-39 135.0 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Bgal_small_N PF02929.17 CRK27451.1 - 5.1e-39 134.3 0.0 1.9e-25 89.9 0.0 2.4 1 1 1 2 2 2 2 Beta galactosidase small chain DUF4981 PF16353.5 CRK27451.1 - 7.6e-15 55.2 0.2 8.2e-14 51.9 0.0 2.8 2 1 0 2 2 2 1 Domain of unknown function(DUF4981) Glyco_hydro_2 PF00703.21 CRK27451.1 - 2.3e-10 41.1 0.0 1.2e-09 38.8 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Sortilin-Vps10 PF15902.5 CRK27453.1 - 6e-19 68.2 2.7 4.4e-06 25.7 0.0 5.8 6 0 0 6 6 6 4 Sortilin, neurotensin receptor 3, BNR PF02012.20 CRK27453.1 - 2.8e-09 35.6 37.9 0.61 10.3 0.6 9.8 9 0 0 9 9 9 7 BNR/Asp-box repeat BNR_2 PF13088.6 CRK27453.1 - 2.4e-06 27.0 16.4 0.21 10.8 0.1 6.7 2 2 3 6 6 6 6 BNR repeat-like domain BNR_6 PF15899.5 CRK27453.1 - 4.5e-05 23.1 4.7 28 5.1 0.0 7.0 7 0 0 7 7 7 1 BNR-Asp box repeat His_Phos_2 PF00328.22 CRK27455.1 - 1.6e-27 96.9 0.0 2e-27 96.5 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Pec_lyase_C PF00544.19 CRK27457.1 - 5.4e-43 147.0 5.8 7.4e-43 146.6 5.8 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 CRK27457.1 - 0.0049 16.7 12.4 0.01 15.7 12.4 1.5 1 1 0 1 1 1 1 Right handed beta helix region MFS_1 PF07690.16 CRK27459.1 - 5.7e-40 137.3 57.6 9.2e-39 133.4 58.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily p450 PF00067.22 CRK27463.1 - 0.00027 19.8 0.0 0.00037 19.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 CRK27467.1 - 1.2e-22 80.3 0.0 7.3e-18 64.6 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 adh_short PF00106.25 CRK27469.1 - 2.1e-39 135.0 0.2 3.4e-39 134.3 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK27469.1 - 1.7e-34 119.4 1.3 2.9e-34 118.7 1.3 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK27469.1 - 4.4e-10 39.8 1.3 2e-09 37.6 1.3 1.9 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 CRK27469.1 - 0.037 13.5 0.9 0.084 12.3 0.1 2.0 3 0 0 3 3 3 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 CRK27469.1 - 0.07 12.5 0.0 0.17 11.2 0.0 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NTP_transf_3 PF12804.7 CRK27469.1 - 0.11 12.8 0.6 0.2 12.0 0.1 1.7 2 0 0 2 2 2 0 MobA-like NTP transferase domain Viral_DNA_bp PF00747.17 CRK27470.1 - 0.098 9.8 0.0 0.1 9.7 0.0 1.0 1 0 0 1 1 1 0 ssDNA binding protein VirK PF06903.12 CRK27470.1 - 0.11 12.5 0.0 0.16 12.1 0.0 1.2 1 0 0 1 1 1 0 VirK protein SIKE PF05769.11 CRK27472.1 - 0.0099 15.8 4.2 0.018 15.0 4.2 1.4 1 0 0 1 1 1 1 SIKE family DUF5094 PF17015.5 CRK27472.1 - 0.8 9.8 4.4 1.3 9.1 4.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) p450 PF00067.22 CRK27474.1 - 2.4e-35 122.2 0.0 2.7e-11 42.9 0.0 4.0 3 1 1 4 4 4 4 Cytochrome P450 HATPase_c PF02518.26 CRK27476.1 - 3.8e-24 85.4 0.1 1.3e-23 83.6 0.1 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 CRK27476.1 - 6.3e-18 65.0 0.0 1.9e-17 63.4 0.0 1.9 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 CRK27476.1 - 7.7e-09 35.5 0.3 2.2e-08 34.0 0.3 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 CRK27476.1 - 0.0029 17.9 0.0 0.0084 16.4 0.0 1.8 1 1 0 1 1 1 1 GAF domain KR PF08659.10 CRK27476.1 - 0.016 15.1 0.1 0.038 13.9 0.1 1.6 1 0 0 1 1 1 0 KR domain FYVE PF01363.21 CRK27480.1 - 0.041 14.0 0.1 0.095 12.8 0.1 1.5 1 0 0 1 1 1 0 FYVE zinc finger DUF2256 PF10013.9 CRK27480.1 - 0.22 11.7 7.5 5.2 7.3 7.5 2.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) MscS_TM PF12794.7 CRK27483.1 - 0.036 12.9 0.6 0.21 10.4 0.0 2.1 2 1 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 SUR7 PF06687.12 CRK27483.1 - 0.058 13.0 3.4 0.27 10.8 0.0 2.4 2 1 1 3 3 3 0 SUR7/PalI family XK-related PF09815.9 CRK27483.1 - 0.52 9.3 5.6 3.1 6.8 5.6 2.1 1 1 0 1 1 1 0 XK-related protein 7tm_7 PF08395.12 CRK27483.1 - 0.85 8.8 3.9 6.2 5.9 0.1 2.3 1 1 1 2 2 2 0 7tm Chemosensory receptor ABC_tran PF00005.27 CRK27484.1 - 1.1e-48 165.2 0.0 1.4e-23 83.9 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 CRK27484.1 - 4.4e-21 74.7 2.3 4.4e-21 74.7 2.3 2.5 4 0 0 4 4 1 1 ABC transporter AAA_21 PF13304.6 CRK27484.1 - 8e-18 65.3 0.9 0.00084 19.2 0.0 4.2 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CRK27484.1 - 1.8e-11 43.9 0.2 0.00098 18.6 0.1 4.4 3 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CRK27484.1 - 5e-09 35.8 0.1 0.0023 17.6 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 CRK27484.1 - 1.5e-08 35.4 0.6 0.017 15.7 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_15 PF13175.6 CRK27484.1 - 1.7e-06 28.0 0.0 0.031 14.0 0.0 2.7 3 0 0 3 3 2 2 AAA ATPase domain AAA_16 PF13191.6 CRK27484.1 - 1.8e-06 28.5 0.0 0.011 16.1 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 CRK27484.1 - 1.8e-06 28.0 0.9 0.0065 16.4 0.0 3.0 3 0 0 3 3 3 2 RsgA GTPase AAA_18 PF13238.6 CRK27484.1 - 2.2e-06 28.2 0.0 0.15 12.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 CRK27484.1 - 2.8e-06 27.8 0.0 0.031 14.7 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 CRK27484.1 - 6.8e-06 26.1 0.0 0.024 14.7 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 CRK27484.1 - 2.4e-05 24.7 0.0 0.11 12.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 CRK27484.1 - 2.4e-05 24.6 0.0 0.011 15.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 CRK27484.1 - 7.7e-05 22.7 0.2 0.21 11.5 0.0 2.8 3 0 0 3 3 2 2 NACHT domain AAA_5 PF07728.14 CRK27484.1 - 0.00012 22.1 0.1 0.75 9.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 CRK27484.1 - 0.00031 21.1 0.0 1.5 9.2 0.0 2.9 2 0 0 2 2 2 2 RNA helicase Roc PF08477.13 CRK27484.1 - 0.0006 20.0 0.0 1.6 9.0 0.0 3.2 2 1 1 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 CRK27484.1 - 0.00062 19.9 0.0 1 9.5 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_14 PF13173.6 CRK27484.1 - 0.0015 18.6 0.0 3.3 7.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 CRK27484.1 - 0.0016 18.2 0.2 2 8.1 0.0 3.4 4 0 0 4 4 4 1 AAA domain NB-ARC PF00931.22 CRK27484.1 - 0.0018 17.5 0.0 4.8 6.3 0.0 3.2 3 0 0 3 3 3 0 NB-ARC domain AAA_27 PF13514.6 CRK27484.1 - 0.0023 17.6 0.2 0.62 9.6 0.0 2.8 3 0 0 3 3 3 1 AAA domain MCM PF00493.23 CRK27484.1 - 0.0054 15.9 0.0 0.62 9.1 0.0 2.3 2 0 0 2 2 2 1 MCM P-loop domain AAA_25 PF13481.6 CRK27484.1 - 0.0062 16.1 0.0 0.98 9.0 0.0 3.1 3 0 0 3 3 3 1 AAA domain Dynamin_N PF00350.23 CRK27484.1 - 0.0067 16.5 0.3 5.4 7.0 0.0 3.1 4 0 0 4 4 3 0 Dynamin family AAA_7 PF12775.7 CRK27484.1 - 0.015 14.8 0.0 1.2 8.6 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF2813 PF11398.8 CRK27484.1 - 0.017 14.4 0.0 4.7 6.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2813) AAA_30 PF13604.6 CRK27484.1 - 0.026 14.3 0.7 3.4 7.3 0.0 3.3 4 1 0 4 4 3 0 AAA domain NTPase_1 PF03266.15 CRK27484.1 - 0.031 14.2 0.1 2.3 8.1 0.1 2.6 2 0 0 2 2 2 0 NTPase AAA_17 PF13207.6 CRK27484.1 - 0.038 14.4 0.0 7.9 6.9 0.0 2.8 2 1 0 2 2 2 0 AAA domain DUF815 PF05673.13 CRK27484.1 - 0.042 13.0 0.1 2.3 7.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ATPase_2 PF01637.18 CRK27484.1 - 0.045 13.7 0.0 5.8 6.8 0.0 2.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Ras PF00071.22 CRK27484.1 - 0.068 12.8 0.1 13 5.4 0.0 3.0 3 0 0 3 3 3 0 Ras family DAP3 PF10236.9 CRK27484.1 - 0.078 12.1 0.9 4.9 6.2 0.1 2.8 2 1 1 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 TsaE PF02367.17 CRK27484.1 - 0.079 13.0 0.2 24 5.0 0.0 3.1 2 1 1 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF87 PF01935.17 CRK27484.1 - 0.081 13.0 0.1 20 5.2 0.0 3.0 2 0 0 2 2 2 0 Helicase HerA, central domain ABC_ATPase PF09818.9 CRK27484.1 - 0.11 11.3 0.3 18 3.9 0.0 3.2 3 0 0 3 3 3 0 Predicted ATPase of the ABC class Pox_D3 PF04580.13 CRK27484.1 - 0.11 12.1 0.2 0.18 11.4 0.2 1.2 1 0 0 1 1 1 0 Chordopoxvirinae D3 protein FeoB_N PF02421.18 CRK27484.1 - 0.13 11.8 0.2 15 5.1 0.1 3.0 3 0 0 3 3 2 0 Ferrous iron transport protein B Rad17 PF03215.15 CRK27484.1 - 0.14 12.0 0.0 22 4.9 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain DUF3584 PF12128.8 CRK27484.1 - 0.15 9.5 0.4 0.44 8.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) PduV-EutP PF10662.9 CRK27484.1 - 0.16 11.7 0.4 11 5.8 0.0 3.1 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation SbcCD_C PF13558.6 CRK27484.1 - 0.2 11.9 0.6 15 5.9 0.1 3.6 3 2 0 3 3 3 0 Putative exonuclease SbcCD, C subunit SNF2_N PF00176.23 CRK27485.1 - 4.9e-66 222.8 1.7 7.3e-66 222.3 0.5 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CRK27485.1 - 1.9e-19 70.0 0.0 4.3e-19 68.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DBINO PF13892.6 CRK27485.1 - 3.5e-10 40.4 0.5 3.5e-10 40.4 0.5 6.7 6 2 1 7 7 7 2 DNA-binding domain ResIII PF04851.15 CRK27485.1 - 4.9e-07 29.9 0.0 4.9e-07 29.9 0.0 3.2 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 CRK27485.1 - 0.16 11.1 0.0 0.16 11.1 0.0 3.2 3 0 0 3 3 3 0 Class II histone deacetylase complex subunits 2 and 3 7TM_GPCR_Srt PF10321.9 CRK27486.1 - 0.0067 15.4 0.9 0.0074 15.3 0.9 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srt PRD1_DD PF11087.8 CRK27486.1 - 0.022 14.5 0.1 0.022 14.5 0.1 2.2 2 2 0 2 2 2 0 PRD1 phage membrane DNA delivery Bd3614-deam PF14439.6 CRK27486.1 - 0.092 12.8 0.3 0.13 12.3 0.3 1.2 1 0 0 1 1 1 0 Bd3614-like deaminase Sugar_tr PF00083.24 CRK27488.1 - 6e-74 249.5 18.2 6.4e-50 170.3 3.5 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CRK27488.1 - 1.8e-14 53.4 40.2 2.2e-11 43.3 14.9 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 CRK27488.1 - 0.00043 19.3 2.4 0.00043 19.3 2.4 1.7 2 0 0 2 2 2 1 MFS_1 like family Glyco_hydro_39 PF01229.17 CRK27488.1 - 0.0005 18.8 0.0 0.00075 18.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 zf-C2H2 PF00096.26 CRK27489.1 - 2e-11 43.7 3.6 0.00013 22.3 0.1 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CRK27489.1 - 5.2e-09 36.1 1.0 5.2e-09 36.1 1.0 3.5 3 1 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 CRK27489.1 - 8.2e-07 29.3 9.2 0.0026 18.4 0.1 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CRK27489.1 - 3.3e-05 23.8 3.2 0.0054 16.7 0.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 CRK27489.1 - 9.4e-05 22.7 1.9 0.29 11.6 0.2 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type Zn_clus PF00172.18 CRK27489.1 - 0.0045 17.1 11.5 0.0045 17.1 11.5 2.6 4 0 0 4 4 4 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HypA PF01155.19 CRK27489.1 - 0.0057 16.7 2.9 0.015 15.3 2.8 1.7 1 1 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2H2_jaz PF12171.8 CRK27489.1 - 0.008 16.4 0.4 1 9.7 0.0 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding RBM1CTR PF08081.11 CRK27489.1 - 0.017 15.2 0.5 0.052 13.6 0.5 1.8 1 0 0 1 1 1 0 RBM1CTR (NUC064) family zf-BED PF02892.15 CRK27489.1 - 0.022 14.7 2.9 1.1 9.4 0.3 2.7 1 1 1 2 2 2 0 BED zinc finger DUF2225 PF09986.9 CRK27489.1 - 0.045 13.5 0.5 5.3 6.7 0.0 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2H2_11 PF16622.5 CRK27489.1 - 0.17 11.7 0.2 0.17 11.7 0.2 3.4 3 1 0 3 3 3 0 zinc-finger C2H2-type zf-CHY PF05495.12 CRK27489.1 - 1.1 9.8 10.3 0.29 11.6 6.0 2.1 1 1 1 2 2 2 0 CHY zinc finger Glyco_hydro_31 PF01055.26 CRK27490.1 - 4.6e-44 151.3 1.0 6.1e-44 150.9 1.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF4968 PF16338.5 CRK27490.1 - 9.5e-06 25.8 0.0 1.5e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4968) Gal_mutarotas_2 PF13802.6 CRK27490.1 - 0.0057 17.0 1.8 0.034 14.5 0.1 2.9 2 2 0 2 2 2 1 Galactose mutarotase-like NPP1 PF05630.11 CRK27491.1 - 1.8e-60 204.4 1.7 2.1e-60 204.2 1.7 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Lipase_3 PF01764.25 CRK27492.1 - 1.3e-06 28.3 0.0 2.6e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 CRK27492.1 - 0.0072 16.9 9.3 0.0072 16.9 9.3 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.13 CRK27492.1 - 0.25 11.1 0.0 0.39 10.4 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DUF3287 PF11690.8 CRK27493.1 - 0.0066 16.2 2.2 0.0066 16.2 2.2 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF3287) DUF812 PF05667.11 CRK27493.1 - 2 7.2 35.5 3.8 6.3 35.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF812) JIP_LZII PF16471.5 CRK27493.1 - 4.6 7.5 17.9 0.075 13.2 1.8 3.4 4 1 1 5 5 5 0 JNK-interacting protein leucine zipper II Spc7 PF08317.11 CRK27493.1 - 9.1 5.1 39.6 4.6 6.0 18.4 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein Hamartin PF04388.12 CRK27494.1 - 0.8 8.3 4.1 1.3 7.6 4.1 1.3 1 0 0 1 1 1 0 Hamartin protein Complex1_LYR PF05347.15 CRK27495.1 - 1.8e-05 24.7 0.2 2.8e-05 24.1 0.2 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 CRK27495.1 - 0.0016 19.2 0.2 0.0023 18.7 0.2 1.3 1 1 0 1 1 1 1 Complex1_LYR-like Methyltransf_25 PF13649.6 CRK27496.1 - 1.9e-11 44.5 0.0 4.6e-11 43.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CRK27496.1 - 5.8e-07 30.1 0.0 1.4e-06 28.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CRK27496.1 - 8.8e-06 25.7 0.0 1.8e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK27496.1 - 0.0011 18.8 0.0 0.0029 17.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK27496.1 - 0.0045 17.7 0.1 0.026 15.3 0.0 2.4 3 0 0 3 3 2 1 Methyltransferase domain PepSY_2 PF13670.6 CRK27496.1 - 0.11 12.5 17.0 1.1 9.3 3.8 3.0 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain ETRAMP PF09716.10 CRK27496.1 - 0.27 11.3 7.3 5.7 7.1 0.5 2.6 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF4148 PF13663.6 CRK27496.1 - 0.66 10.2 29.7 0.041 14.1 1.4 5.0 5 0 0 5 5 5 0 Domain of unknown function (DUF4148) PsaN PF05479.11 CRK27496.1 - 1.8 8.8 7.4 3.3 7.9 1.8 2.7 2 0 0 2 2 2 0 Photosystem I reaction centre subunit N (PSAN or PSI-N) WRNPLPNID PF15017.6 CRK27496.1 - 1.8 9.5 11.7 1.9 9.4 0.6 3.2 3 0 0 3 3 3 0 Putative WW-binding domain and destruction box DUF732 PF05305.14 CRK27496.1 - 9.9 6.6 15.3 14 6.1 3.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF732) LRR_8 PF13855.6 CRK27498.1 - 4.2e-08 32.8 4.4 3.2e-05 23.6 0.3 2.4 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 CRK27498.1 - 8.3e-07 29.2 1.4 0.0013 19.1 0.2 2.9 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) Exo_endo_phos PF03372.23 CRK27498.1 - 1.6e-06 27.8 0.0 2.9e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family adh_short_C2 PF13561.6 CRK27499.1 - 4.6e-57 193.3 3.0 5.7e-57 193.0 3.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRK27499.1 - 5.4e-47 159.8 3.1 7e-47 159.4 3.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Ecm33 PF12454.8 CRK27499.1 - 0.21 11.8 2.4 8.3 6.6 0.0 2.7 2 0 0 2 2 2 0 GPI-anchored cell wall organization protein Abhydrolase_3 PF07859.13 CRK27500.1 - 4.1e-48 164.0 0.0 1.1e-47 162.7 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.28 CRK27500.1 - 1.9e-10 40.2 0.0 1.5e-09 37.3 0.0 2.1 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 CRK27500.1 - 3.4e-05 24.6 0.9 4.8e-05 24.1 0.9 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 CRK27500.1 - 0.056 12.9 0.3 8.9 5.7 0.0 3.5 3 1 1 4 4 4 0 Prolyl oligopeptidase family Pyr_redox_3 PF13738.6 CRK27501.1 - 2.9e-14 53.0 0.0 1.1e-13 51.1 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 CRK27501.1 - 8.6e-14 50.8 0.0 1.4e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 CRK27501.1 - 2.7e-11 43.2 0.0 1e-09 38.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CRK27501.1 - 1e-08 34.7 0.1 8.8e-07 28.4 0.1 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 CRK27501.1 - 4.3e-06 26.9 0.4 2.5e-05 24.4 0.0 2.5 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CRK27501.1 - 1.8e-05 24.5 0.0 0.17 11.4 0.0 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CRK27501.1 - 0.00053 19.2 0.0 0.0012 18.0 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain 2-Hacid_dh_C PF02826.19 CRK27501.1 - 0.0026 17.1 0.0 0.0054 16.1 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 CRK27501.1 - 0.0042 17.1 0.0 0.028 14.5 0.0 2.1 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 CRK27501.1 - 0.014 14.2 0.0 0.88 8.2 0.0 2.3 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_3 PF01494.19 CRK27501.1 - 0.08 12.2 0.2 0.44 9.7 0.3 2.0 1 1 1 2 2 2 0 FAD binding domain Thi4 PF01946.17 CRK27501.1 - 0.089 12.0 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Thi4 family SBP_bac_3 PF00497.20 CRK27501.1 - 0.1 12.0 0.0 0.47 9.8 0.0 1.9 2 0 0 2 2 2 0 Bacterial extracellular solute-binding proteins, family 3 Lactamase_B PF00753.27 CRK27502.1 - 3.9e-09 36.8 0.1 6.4e-09 36.1 0.1 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CRK27502.1 - 0.0095 15.5 0.0 0.025 14.1 0.0 1.8 2 1 0 2 2 2 1 Beta-lactamase superfamily domain MFS_1 PF07690.16 CRK27504.1 - 5.4e-37 127.5 34.4 5.4e-37 127.5 34.4 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 CRK27505.1 - 4.6e-13 48.8 0.5 7.7e-13 48.1 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK27505.1 - 0.0045 17.1 11.3 0.0077 16.3 11.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FMO-like PF00743.19 CRK27507.1 - 7.7e-15 54.3 0.0 4.5e-14 51.8 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 CRK27507.1 - 4.9e-09 36.3 0.0 1.4e-08 34.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 CRK27507.1 - 7.3e-09 35.3 0.0 4.8e-07 29.3 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CRK27507.1 - 1.5e-05 24.4 0.0 0.019 14.2 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CRK27507.1 - 0.00065 18.9 0.1 0.0075 15.5 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 CRK27507.1 - 0.0029 17.6 1.1 0.19 11.7 0.0 3.5 4 0 0 4 4 4 1 FAD-NAD(P)-binding Thi4 PF01946.17 CRK27507.1 - 0.0044 16.3 0.0 4.2 6.5 0.0 2.8 3 0 0 3 3 3 2 Thi4 family adh_short PF00106.25 CRK27508.1 - 7.3e-31 107.2 0.0 9.7e-31 106.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK27508.1 - 4.1e-23 82.2 0.0 5.8e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK27508.1 - 4.3e-08 33.3 0.0 1.4e-05 25.1 0.0 2.2 2 0 0 2 2 2 2 KR domain 3Beta_HSD PF01073.19 CRK27508.1 - 0.023 13.7 0.0 0.032 13.2 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Exo_endo_phos PF03372.23 CRK27509.1 - 3e-09 36.8 0.1 3.7e-09 36.4 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 CRK27509.1 - 0.1 12.4 0.0 0.26 11.1 0.0 1.6 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase SR-25 PF10500.9 CRK27510.1 - 2 8.0 31.6 0.6 9.7 20.1 2.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF4614 PF15391.6 CRK27510.1 - 2.6 8.0 19.1 0.35 10.8 1.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) RPN2_C PF18004.1 CRK27510.1 - 8.5 6.3 11.3 13 5.7 0.2 2.3 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF3915 PF13054.6 CRK27510.1 - 9.3 6.3 6.9 25 4.9 6.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) HET PF06985.11 CRK27511.1 - 2.5e-07 31.2 10.8 2e-05 25.0 0.2 3.7 3 1 1 4 4 4 2 Heterokaryon incompatibility protein (HET) RPN2_C PF18004.1 CRK27511.1 - 0.23 11.4 7.8 0.6 10.0 7.8 1.6 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Med19 PF10278.9 CRK27511.1 - 7.2 6.5 13.3 14 5.6 13.3 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 p450 PF00067.22 CRK27513.1 - 2.2e-43 148.7 0.2 2.4e-43 148.6 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4317 PF14199.6 CRK27513.1 - 0.056 12.6 0.1 0.079 12.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4317) ubiquitin PF00240.23 CRK27514.1 - 7.3e-07 28.9 0.0 1.3e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 CRK27514.1 - 4.1e-05 24.1 1.6 5.2e-05 23.8 0.0 1.9 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Rad60-SLD PF11976.8 CRK27514.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like PS_Dcarbxylase PF02666.15 CRK27515.1 - 1.8e-67 226.8 0.0 7.9e-66 221.4 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase Nitroreductase PF00881.24 CRK27516.1 - 2.9e-14 53.5 0.0 3.5e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family PriCT_1 PF08708.11 CRK27516.1 - 0.16 11.7 0.1 0.26 11.0 0.1 1.3 1 0 0 1 1 1 0 Primase C terminal 1 (PriCT-1) FAD_binding_1 PF00667.20 CRK27518.1 - 4.1e-44 150.8 0.0 5.5e-44 150.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 CRK27518.1 - 6.5e-09 36.4 0.0 2.1e-08 34.8 0.0 1.9 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Aldedh PF00171.22 CRK27519.1 - 1.7e-95 320.2 2.8 4e-66 223.4 0.4 3.2 1 1 1 3 3 3 3 Aldehyde dehydrogenase family Amino_oxidase PF01593.24 CRK27519.1 - 9.9e-50 170.1 0.0 1.9e-49 169.2 0.0 1.5 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CRK27519.1 - 4.5e-13 49.2 0.2 1.9e-12 47.2 0.2 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CRK27519.1 - 2.9e-08 33.2 1.2 1.2e-07 31.2 1.3 1.8 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 CRK27519.1 - 1e-07 31.7 0.6 2.1e-07 30.6 0.6 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pkinase PF00069.25 CRK27519.1 - 3e-06 26.8 0.0 5.6e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain DAO PF01266.24 CRK27519.1 - 3.5e-06 26.8 0.1 7.9e-06 25.7 0.1 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 CRK27519.1 - 6.6e-06 25.5 0.3 1.2e-05 24.6 0.3 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 CRK27519.1 - 1.4e-05 24.0 0.4 2.4e-05 23.2 0.4 1.3 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 CRK27519.1 - 8.4e-05 21.8 0.2 0.00068 18.8 0.1 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Kdo PF06293.14 CRK27519.1 - 0.00015 21.2 0.0 0.00033 20.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pyr_redox_2 PF07992.14 CRK27519.1 - 0.00077 18.8 1.1 0.0015 17.8 0.5 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CRK27519.1 - 0.00078 20.0 0.2 0.0029 18.1 0.2 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CRK27519.1 - 0.0012 18.0 1.0 0.016 14.2 0.9 2.5 3 0 0 3 3 3 1 Lycopene cyclase protein APH PF01636.23 CRK27519.1 - 0.0034 17.3 0.1 0.0086 16.0 0.0 1.7 2 0 0 2 2 1 1 Phosphotransferase enzyme family Pyr_redox_3 PF13738.6 CRK27519.1 - 0.0038 16.5 0.2 0.017 14.4 0.2 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 CRK27519.1 - 0.048 12.9 0.7 0.12 11.6 0.7 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 CRK27519.1 - 0.16 11.1 0.7 0.38 10.0 0.3 1.8 2 0 0 2 2 2 0 FAD binding domain Fungal_trans PF04082.18 CRK27520.1 - 2.7e-13 49.5 0.8 1.7e-12 47.0 0.8 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain N2227 PF07942.12 CRK27521.1 - 7.2e-79 264.8 0.0 9.1e-79 264.5 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.6 CRK27521.1 - 4.2e-06 26.7 0.0 7.4e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK27521.1 - 0.00043 21.0 0.0 0.032 15.0 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 CRK27521.1 - 0.00073 20.1 0.0 0.028 15.1 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK27521.1 - 0.023 14.5 0.0 0.32 10.8 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.6 CRK27521.1 - 0.051 14.3 0.0 2.4 8.9 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain BSD PF03909.17 CRK27524.1 - 0.13 12.3 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 BSD domain Trypan_PARP PF05887.11 CRK27524.1 - 0.16 11.9 2.2 0.84 9.6 1.5 2.1 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Med30 PF11315.8 CRK27525.1 - 0.0023 18.2 0.0 0.0063 16.7 0.0 1.8 1 0 0 1 1 1 1 Mediator complex subunit 30 Scaffolding_pro PF11418.8 CRK27525.1 - 0.024 15.2 0.8 0.96 10.0 0.5 2.5 2 0 0 2 2 2 0 Phi29 scaffolding protein DUF4207 PF13904.6 CRK27525.1 - 0.025 14.3 0.2 0.058 13.1 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) Laminin_II PF06009.12 CRK27525.1 - 0.067 13.2 0.1 0.19 11.7 0.1 1.7 1 0 0 1 1 1 0 Laminin Domain II Enkurin PF13864.6 CRK27525.1 - 2.3 8.7 7.5 89 3.6 7.5 2.9 1 1 0 1 1 1 0 Calmodulin-binding Torus PF16131.5 CRK27526.1 - 0.045 14.5 2.1 0.13 13.0 2.1 1.7 1 0 0 1 1 1 0 Torus domain zf-CCCH_3 PF15663.5 CRK27526.1 - 0.051 13.8 1.6 0.18 12.1 1.1 2.0 2 0 0 2 2 2 0 Zinc-finger containing family SPRY PF00622.28 CRK27528.1 - 3.2e-20 72.4 0.1 5.5e-20 71.7 0.1 1.4 1 0 0 1 1 1 1 SPRY domain Zn_clus PF00172.18 CRK27529.1 - 6.5e-08 32.6 11.1 1e-07 31.9 11.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 CRK27529.1 - 2.8e-05 23.1 0.2 5.8e-05 22.1 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Wbp11 PF09429.10 CRK27529.1 - 0.26 11.7 1.8 0.41 11.1 1.8 1.3 1 0 0 1 1 1 0 WW domain binding protein 11 HEAT_EZ PF13513.6 CRK27530.1 - 1.2e-34 118.3 10.7 1.6e-15 57.3 0.1 10.7 10 1 2 12 12 10 3 HEAT-like repeat HEAT PF02985.22 CRK27530.1 - 2.8e-27 92.4 10.4 6.9e-06 25.9 0.0 10.4 11 0 0 11 11 10 6 HEAT repeat HEAT_2 PF13646.6 CRK27530.1 - 3.5e-21 75.4 4.2 1.1e-06 29.0 0.0 7.8 5 4 4 9 9 8 3 HEAT repeats MMS19_C PF12460.8 CRK27530.1 - 1.8e-15 57.0 7.3 0.0003 20.0 0.0 5.1 4 1 0 4 4 4 3 RNAPII transcription regulator C-terminal Cnd1 PF12717.7 CRK27530.1 - 2.8e-13 50.2 0.6 0.04 14.0 0.0 6.3 5 2 0 5 5 5 4 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 CRK27530.1 - 7.9e-10 39.2 0.0 0.0032 18.0 0.0 6.0 4 2 3 7 7 7 3 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 CRK27530.1 - 5.4e-09 35.1 0.1 0.014 14.0 0.1 4.5 2 2 0 4 4 4 2 Adaptin N terminal region CLASP_N PF12348.8 CRK27530.1 - 9.1e-07 28.7 0.6 2.5 7.6 0.0 5.8 6 1 0 6 6 5 2 CLASP N terminal RTP1_C1 PF10363.9 CRK27530.1 - 9.5e-06 25.8 0.5 0.0096 16.1 0.0 4.0 4 0 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 IBN_N PF03810.19 CRK27530.1 - 2.2e-05 24.3 0.3 0.00095 19.0 0.1 3.9 2 1 0 2 2 2 1 Importin-beta N-terminal domain DUF3437 PF11919.8 CRK27530.1 - 0.00023 21.0 1.8 1.1 9.2 0.0 5.0 4 2 2 6 6 6 1 Domain of unknown function (DUF3437) Telomere_reg-2 PF10193.9 CRK27530.1 - 0.0012 19.3 0.4 0.29 11.6 0.0 4.1 3 1 1 4 4 4 1 Telomere length regulation protein UME PF08064.13 CRK27530.1 - 0.0055 16.6 0.1 2.8 7.9 0.0 4.5 4 1 0 4 4 4 1 UME (NUC010) domain HEAT_PBS PF03130.16 CRK27530.1 - 0.0081 16.7 0.5 31 5.7 0.1 4.7 4 0 0 4 4 3 0 PBS lyase HEAT-like repeat Gcn1_N PF12074.8 CRK27530.1 - 0.013 14.9 0.1 3.6 6.8 0.0 3.5 3 1 0 3 3 3 0 Generalcontrol nonderepressible 1 (Gcn1) N-terminal RIX1 PF08167.12 CRK27530.1 - 0.024 14.4 0.3 64 3.2 0.0 4.4 4 1 0 4 4 4 0 rRNA processing/ribosome biogenesis Arm PF00514.23 CRK27530.1 - 0.027 14.5 5.5 7.9 6.7 0.0 6.5 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat Myf5 PF12232.8 CRK27530.1 - 0.068 13.9 0.0 0.33 11.8 0.0 2.1 2 0 0 2 2 2 0 Myogenic determination factor 5 Homeobox_KN PF05920.11 CRK27531.1 - 7.6e-19 67.3 0.0 1.4e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 CRK27531.1 - 9.9e-09 34.9 0.1 2.1e-08 33.9 0.1 1.5 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 CRK27531.1 - 0.0072 15.8 0.3 0.041 13.3 0.1 2.1 2 0 0 2 2 2 1 Homeodomain leucine-zipper encoding, Homez zf-C2H2 PF00096.26 CRK27531.1 - 0.01 16.2 17.3 1.1 9.9 1.0 4.0 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CRK27531.1 - 0.056 14.3 2.7 0.056 14.3 2.7 4.7 4 0 0 4 4 4 0 C2H2-type zinc finger HTH_36 PF13730.6 CRK27531.1 - 0.18 11.8 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Zn_clus PF00172.18 CRK27531.1 - 2.6 8.2 10.8 0.42 10.8 5.3 2.5 2 1 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M20 PF01546.28 CRK27533.1 - 1.3e-31 109.9 0.1 3.5e-31 108.5 0.1 1.8 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DUF3328 PF11807.8 CRK27533.1 - 3.7e-19 69.4 2.6 8.3e-19 68.2 2.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Methyltransf_25 PF13649.6 CRK27533.1 - 0.00037 21.1 0.0 0.042 14.6 0.0 3.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 CRK27533.1 - 0.0016 19.1 0.0 0.0089 16.7 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain M20_dimer PF07687.14 CRK27533.1 - 0.011 15.6 0.1 0.028 14.3 0.1 1.7 1 0 0 1 1 1 0 Peptidase dimerisation domain Peptidase_M28 PF04389.17 CRK27533.1 - 0.025 14.3 0.0 0.061 13.0 0.0 1.7 1 0 0 1 1 1 0 Peptidase family M28 Methyltransf_23 PF13489.6 CRK27533.1 - 0.13 12.1 0.0 0.43 10.4 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain CAF1 PF04857.20 CRK27535.1 - 4.7e-19 68.7 0.0 4.1e-09 36.1 0.0 2.1 2 0 0 2 2 2 2 CAF1 family ribonuclease RFX_DNA_binding PF02257.15 CRK27535.1 - 0.12 13.0 0.0 0.55 10.9 0.0 2.0 2 0 0 2 2 2 0 RFX DNA-binding domain CLTH PF10607.9 CRK27536.1 - 7.2e-32 110.3 0.1 1.2e-31 109.7 0.1 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain BACK PF07707.15 CRK27536.1 - 0.0077 16.3 0.1 0.035 14.2 0.1 2.1 1 0 0 1 1 1 1 BTB And C-terminal Kelch LisH PF08513.11 CRK27536.1 - 0.03 14.3 0.0 0.092 12.7 0.0 1.9 1 0 0 1 1 1 0 LisH NRDE-2 PF08424.10 CRK27537.1 - 3.6e-95 318.8 0.1 3.6e-95 318.8 0.1 2.5 3 0 0 3 3 3 1 NRDE-2, necessary for RNA interference eIF-6 PF01912.18 CRK27537.1 - 2.2e-34 118.6 0.0 4.9e-34 117.5 0.0 1.5 1 0 0 1 1 1 1 eIF-6 family CAF1 PF04857.20 CRK27537.1 - 1.5e-09 37.5 0.1 1.5e-09 37.5 0.1 2.0 2 0 0 2 2 2 1 CAF1 family ribonuclease HLH PF00010.26 CRK27537.1 - 2e-08 34.1 1.6 2.9e-08 33.5 0.3 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain TPR_14 PF13428.6 CRK27537.1 - 0.00067 20.3 3.9 6.5 7.9 0.4 5.5 3 1 1 4 4 4 1 Tetratricopeptide repeat DUF5595 PF18077.1 CRK27537.1 - 0.64 10.1 7.3 5.5 7.1 0.5 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) DUF2841 PF11001.8 CRK27538.1 - 1.3e-88 293.3 20.3 4.1e-44 149.6 6.2 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF2841) CLTH PF10607.9 CRK27538.1 - 8.5e-32 110.1 0.1 1.6e-31 109.2 0.1 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain DUF1644 PF07800.12 CRK27538.1 - 0.0019 18.3 2.3 8.3 6.4 0.0 3.5 3 0 0 3 3 3 2 Protein of unknown function (DUF1644) SgrT PF15894.5 CRK27538.1 - 0.062 13.3 0.8 15 5.7 0.1 2.6 2 0 0 2 2 2 0 Inhibitor of glucose uptake transporter SgrT NinE PF05322.11 CRK27538.1 - 0.065 13.1 0.2 18 5.3 0.0 2.5 2 0 0 2 2 2 0 NINE Protein RNA_pol_L_2 PF13656.6 CRK27538.1 - 0.085 12.6 0.6 20 5.0 0.1 2.7 2 0 0 2 2 2 0 RNA polymerase Rpb3/Rpb11 dimerisation domain LisH PF08513.11 CRK27538.1 - 0.1 12.6 0.0 0.34 10.9 0.0 2.0 1 0 0 1 1 1 0 LisH Fib_alpha PF08702.10 CRK27538.1 - 0.43 10.7 1.7 36 4.5 0.1 2.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family PSD5 PF07637.11 CRK27538.1 - 0.45 10.9 1.9 47 4.4 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1595) Sec34 PF04136.15 CRK27538.1 - 2.1 8.2 14.4 2 8.3 0.1 4.0 6 0 0 6 6 6 0 Sec34-like family Phage_GP20 PF06810.11 CRK27538.1 - 3 7.6 6.9 19 5.0 0.8 2.6 2 0 0 2 2 2 0 Phage minor structural protein GP20 MSP7_C PF12948.7 CRK27538.1 - 3.5 8.3 7.2 25 5.5 0.8 2.5 2 0 0 2 2 2 0 MSP7-like protein C-terminal domain HLH PF00010.26 CRK27539.1 - 1.6e-11 44.0 1.3 3.5e-11 42.9 1.3 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TFIIA PF03153.13 CRK27539.1 - 0.021 14.9 37.3 0.031 14.3 37.3 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AAA_28 PF13521.6 CRK27539.1 - 0.57 10.4 0.0 0.57 10.4 0.0 2.4 3 0 0 3 3 3 0 AAA domain Dicty_REP PF05086.12 CRK27539.1 - 0.9 7.4 5.7 1.4 6.8 5.7 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein ABC_membrane PF00664.23 CRK27540.1 - 7.9e-88 294.7 26.4 9.3e-45 153.4 9.2 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CRK27540.1 - 8.1e-63 211.0 0.5 3e-30 105.5 0.1 3.8 4 0 0 4 4 3 3 ABC transporter Pro-kuma_activ PF09286.11 CRK27540.1 - 1.2e-33 116.5 0.0 3.2e-33 115.0 0.0 1.8 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain SMC_N PF02463.19 CRK27540.1 - 2.9e-14 53.1 2.4 0.00089 18.8 0.0 5.0 3 2 1 4 4 4 4 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 CRK27540.1 - 5.1e-05 23.3 0.6 0.33 11.0 0.3 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CRK27540.1 - 0.00048 20.1 0.4 0.78 9.6 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase ABC_membrane_2 PF06472.15 CRK27540.1 - 0.0098 15.3 0.1 0.0098 15.3 0.1 2.4 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 AAA_16 PF13191.6 CRK27540.1 - 0.013 15.9 0.4 0.36 11.2 0.1 2.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 CRK27540.1 - 0.018 14.8 0.6 4.2 7.2 0.1 2.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain Dynamin_N PF00350.23 CRK27540.1 - 0.019 15.0 4.3 0.19 11.8 0.1 2.9 3 0 0 3 3 3 0 Dynamin family DUF87 PF01935.17 CRK27540.1 - 0.026 14.6 0.7 1.1 9.3 0.2 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain UPF0093 PF03653.13 CRK27540.1 - 0.045 14.0 0.3 0.045 14.0 0.3 2.1 2 0 0 2 2 1 0 Uncharacterised protein family (UPF0093) AAA_23 PF13476.6 CRK27540.1 - 0.079 13.5 0.1 9.3 6.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 CRK27540.1 - 0.11 12.3 1.8 9.7 5.9 0.5 2.5 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 CRK27540.1 - 0.12 12.1 1.0 3.9 7.1 0.0 3.0 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CRK27540.1 - 0.14 12.5 0.3 16 5.9 0.0 3.4 3 0 0 3 3 3 0 RNA helicase AAA_15 PF13175.6 CRK27540.1 - 0.39 10.4 1.0 6.2 6.4 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain DUF3446 PF11928.8 CRK27540.1 - 0.64 10.4 19.2 1 9.7 2.6 3.3 3 0 0 3 3 3 0 Early growth response N-terminal domain Use1 PF09753.9 CRK27541.1 - 8 6.1 6.6 15 5.2 6.6 1.3 1 0 0 1 1 1 0 Membrane fusion protein Use1 HEAT PF02985.22 CRK27542.1 - 2.6e-12 45.9 0.0 0.079 13.3 0.0 4.2 4 0 0 4 4 4 4 HEAT repeat HEAT_2 PF13646.6 CRK27542.1 - 4.8e-05 23.7 0.0 0.18 12.2 0.0 2.9 2 1 0 3 3 3 2 HEAT repeats HEAT_EZ PF13513.6 CRK27542.1 - 0.004 17.6 0.0 6.6 7.4 0.0 3.4 3 0 0 3 3 3 1 HEAT-like repeat Med24_N PF11277.8 CRK27542.1 - 0.023 12.8 0.0 0.03 12.4 0.0 1.0 1 0 0 1 1 1 0 Mediator complex subunit 24 N-terminal Methyltransf_31 PF13847.6 CRK27543.1 - 2.8e-12 46.7 0.0 3.2e-08 33.5 0.0 3.5 2 1 1 3 3 3 2 Methyltransferase domain Methyltransf_11 PF08241.12 CRK27543.1 - 3.3e-06 27.6 0.6 0.00025 21.6 0.1 3.8 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK27543.1 - 1e-05 26.1 0.1 1e-05 26.1 0.1 3.1 5 0 0 5 5 5 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK27543.1 - 3.7e-05 24.4 3.7 8.1e-05 23.3 0.1 3.6 5 0 0 5 5 5 1 Methyltransferase domain Methyltransf_23 PF13489.6 CRK27543.1 - 0.00014 21.8 0.0 0.00014 21.8 0.0 2.7 4 0 0 4 4 4 1 Methyltransferase domain AdoMet_MTase PF07757.13 CRK27543.1 - 0.0024 18.2 0.0 0.0059 16.9 0.0 1.6 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase MTS PF05175.14 CRK27543.1 - 0.0048 16.5 0.1 0.014 14.9 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 CRK27543.1 - 0.019 15.0 0.0 0.019 15.0 0.0 2.4 3 0 0 3 3 3 0 Methyltransferase domain MetW PF07021.12 CRK27543.1 - 0.029 14.0 0.0 0.064 12.9 0.0 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW DUF3148 PF11347.8 CRK27543.1 - 0.11 12.3 0.6 5.8 6.8 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3148) HEAT PF02985.22 CRK27544.1 - 5.5e-29 97.7 16.6 0.0071 16.5 0.1 9.4 10 0 0 10 10 10 7 HEAT repeat HEAT_2 PF13646.6 CRK27544.1 - 4.4e-27 94.3 8.4 2.5e-07 31.0 0.0 6.3 2 2 4 6 6 6 5 HEAT repeats HEAT_EZ PF13513.6 CRK27544.1 - 5.2e-10 39.6 6.6 0.07 13.7 0.0 6.5 6 2 1 7 7 7 2 HEAT-like repeat Cnd1 PF12717.7 CRK27544.1 - 1e-09 38.7 7.5 0.0032 17.5 0.2 4.9 3 1 1 5 5 5 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 CRK27544.1 - 2.2e-09 37.8 3.6 0.0014 19.2 0.2 6.0 3 1 4 7 7 7 2 Vacuolar 14 Fab1-binding region RTP1_C1 PF10363.9 CRK27544.1 - 1.1e-07 32.0 4.7 0.12 12.6 0.1 4.8 4 1 1 5 5 5 2 Required for nuclear transport of RNA pol II C-terminus 1 Adaptin_N PF01602.20 CRK27544.1 - 1.6e-07 30.3 2.2 0.0016 17.1 0.1 3.8 1 1 2 4 4 4 2 Adaptin N terminal region CLASP_N PF12348.8 CRK27544.1 - 0.0005 19.7 1.3 0.031 13.8 0.1 3.5 1 1 1 3 3 3 1 CLASP N terminal Proteasom_PSMB PF10508.9 CRK27544.1 - 0.007 14.9 4.9 0.24 9.8 0.1 2.4 2 1 0 2 2 2 2 Proteasome non-ATPase 26S subunit Ecm29 PF13001.7 CRK27544.1 - 0.022 13.4 5.0 0.094 11.4 0.1 2.8 3 0 0 3 3 3 0 Proteasome stabiliser M11L PF11099.8 CRK27544.1 - 0.026 14.8 0.7 6.4 7.0 0.1 3.4 1 1 1 3 3 3 0 Apoptosis regulator M11L like IFRD PF05004.13 CRK27544.1 - 0.2 10.7 2.0 1.8 7.6 0.4 3.0 2 1 0 2 2 2 0 Interferon-related developmental regulator (IFRD) Trp_Tyr_perm PF03222.13 CRK27544.1 - 0.22 10.5 0.0 0.36 9.8 0.0 1.2 1 0 0 1 1 1 0 Tryptophan/tyrosine permease family Arm PF00514.23 CRK27544.1 - 0.69 10.0 7.3 8.9 6.5 0.0 4.6 7 0 0 7 7 5 0 Armadillo/beta-catenin-like repeat tRNA_synthFbeta PF17759.1 CRK27545.1 - 1.1e-46 159.0 0.0 1.7e-46 158.3 0.0 1.3 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 CRK27545.1 - 1.5e-30 105.3 0.7 2.1e-29 101.5 0.2 2.4 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 CRK27545.1 - 3.7e-26 91.9 0.1 6.3e-26 91.1 0.1 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 CRK27545.1 - 1.2e-14 54.3 0.0 1.6e-11 44.3 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetase B5 domain Myotub-related PF06602.14 CRK27547.1 - 5e-127 423.7 0.0 6.8e-127 423.2 0.0 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain MCPVI PF02993.14 CRK27547.1 - 0.016 15.0 0.2 0.079 12.8 0.1 2.1 2 0 0 2 2 2 0 Minor capsid protein VI Y_phosphatase3 PF13350.6 CRK27547.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family Mg_trans_NIPA PF05653.14 CRK27548.1 - 6.7e-106 353.7 20.1 4.2e-95 318.3 13.7 2.0 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 CRK27548.1 - 0.00026 21.2 6.9 0.00026 21.2 6.9 4.6 4 1 0 4 4 4 1 EamA-like transporter family DUF4536 PF15055.6 CRK27548.1 - 0.032 14.5 0.1 24 5.3 0.0 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4536) SpaA PF17802.1 CRK27548.1 - 0.12 12.7 1.3 6.5 7.2 0.1 2.5 2 0 0 2 2 2 0 Prealbumin-like fold domain Big_2 PF02368.18 CRK27548.1 - 0.64 10.0 3.3 11 6.0 0.4 2.5 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 2) Glycos_transf_4 PF00953.21 CRK27548.1 - 2.1 8.3 23.6 2.2 8.2 0.0 4.3 2 1 1 4 4 4 0 Glycosyl transferase family 4 DUF2420 PF10336.9 CRK27549.1 - 4.6e-06 26.6 0.1 1e-05 25.5 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) Adap_comp_sub PF00928.21 CRK27550.1 - 2.4e-17 63.2 0.0 3.1e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CRK27550.1 - 0.022 14.7 0.0 0.063 13.2 0.0 1.8 1 1 0 1 1 1 0 Clathrin adaptor complex small chain Cu_amine_oxid PF01179.20 CRK27551.1 - 6.3e-154 512.8 0.0 7.7e-154 512.5 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 CRK27551.1 - 3.4e-19 69.1 0.0 7.4e-19 68.0 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 CRK27551.1 - 1.7e-11 44.2 0.1 3.7e-11 43.1 0.1 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain RINGv PF12906.7 CRK27551.1 - 0.045 13.9 0.1 12 6.1 0.0 2.7 2 0 0 2 2 2 0 RING-variant domain AA_permease_2 PF13520.6 CRK27552.1 - 1.7e-54 185.3 49.5 2.1e-54 185.0 49.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CRK27552.1 - 1.7e-15 56.6 37.4 2.2e-15 56.2 37.4 1.1 1 0 0 1 1 1 1 Amino acid permease STAT1_TAZ2bind PF12162.8 CRK27553.1 - 0.2 11.2 0.8 0.37 10.4 0.8 1.4 1 0 0 1 1 1 0 STAT1 TAZ2 binding domain Hydrolase_4 PF12146.8 CRK27554.1 - 0.029 13.6 0.0 0.053 12.8 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 LCAT PF02450.15 CRK27554.1 - 0.059 12.5 0.0 0.094 11.9 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Peptidase_S9 PF00326.21 CRK27554.1 - 0.21 11.0 0.0 0.57 9.6 0.0 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 CRK27554.1 - 6.7 7.3 14.2 0.74 10.4 4.2 3.3 3 1 0 3 3 3 0 Alpha/beta hydrolase family His_Phos_2 PF00328.22 CRK27555.1 - 5e-16 59.0 0.0 5.8e-15 55.5 0.0 2.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RRM_1 PF00076.22 CRK27556.1 - 7.1e-36 121.9 0.1 6.4e-11 41.9 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CRK27556.1 - 3.2e-16 58.9 0.0 0.0055 16.5 0.0 4.3 4 0 0 4 4 4 4 Occluded RNA-recognition motif RRM PF10378.9 CRK27556.1 - 3e-08 33.2 2.8 3e-08 33.2 2.8 2.6 2 0 0 2 2 2 1 Putative RRM domain DUF4523 PF15023.6 CRK27556.1 - 3.8e-06 26.8 0.0 0.01 15.7 0.0 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF4523) RRM_7 PF16367.5 CRK27556.1 - 1.9e-05 24.7 0.0 0.0061 16.7 0.0 3.2 4 0 0 4 4 4 1 RNA recognition motif RRM_Rrp7 PF17799.1 CRK27556.1 - 0.01 15.6 0.0 0.72 9.6 0.0 3.4 2 1 1 3 3 3 0 Rrp7 RRM-like N-terminal domain RRM_3 PF08777.11 CRK27556.1 - 0.018 15.1 0.1 2.4 8.3 0.1 2.9 3 0 0 3 3 3 0 RNA binding motif TipAS PF07739.13 CRK27560.1 - 0.019 15.5 1.0 0.089 13.3 0.7 2.3 1 1 1 2 2 2 0 TipAS antibiotic-recognition domain DASH_Dam1 PF08653.10 CRK27560.1 - 0.019 14.7 2.4 0.51 10.2 0.2 3.4 3 0 0 3 3 3 0 DASH complex subunit Dam1 Adenylsucc_synt PF00709.21 CRK27560.1 - 0.031 13.2 1.1 0.046 12.6 1.1 1.2 1 0 0 1 1 1 0 Adenylosuccinate synthetase Leu_zip PF15294.6 CRK27560.1 - 0.05 13.1 12.8 0.64 9.5 11.1 2.1 1 1 1 2 2 2 0 Leucine zipper TPR_MLP1_2 PF07926.12 CRK27560.1 - 0.26 11.3 14.2 0.39 10.8 9.1 2.8 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Apolipoprotein PF01442.18 CRK27560.1 - 0.28 11.0 9.9 0.68 9.8 9.8 1.7 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain UBN_AB PF14075.6 CRK27560.1 - 0.3 10.8 8.0 1.1 9.0 8.0 2.0 1 1 0 1 1 1 0 Ubinuclein conserved middle domain ApoLp-III PF07464.11 CRK27560.1 - 0.31 11.1 7.2 0.84 9.7 2.4 2.8 1 1 2 3 3 3 0 Apolipophorin-III precursor (apoLp-III) DUF1640 PF07798.11 CRK27560.1 - 0.45 10.5 11.7 0.94 9.5 10.9 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) Ntox28 PF15605.6 CRK27560.1 - 0.86 9.9 8.6 0.72 10.1 2.0 2.9 3 1 0 3 3 3 0 Bacterial toxin 28 LPP PF04728.13 CRK27560.1 - 0.91 10.0 5.7 6.4 7.2 0.8 3.5 3 1 1 4 4 3 0 Lipoprotein leucine-zipper Phasin PF05597.11 CRK27560.1 - 1.2 9.2 9.3 2.9 7.9 2.7 3.1 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF1690 PF07956.11 CRK27560.1 - 1.3 9.5 11.2 1.3 9.5 2.6 2.2 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) RB_A PF01858.17 CRK27560.1 - 1.4 8.7 6.0 5.7 6.7 0.3 2.1 1 1 1 2 2 2 0 Retinoblastoma-associated protein A domain Lectin_N PF03954.14 CRK27560.1 - 1.4 8.6 6.4 0.85 9.4 1.2 2.5 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain Sirohm_synth_C PF14823.6 CRK27560.1 - 1.6 8.4 4.8 3.4 7.4 0.7 3.3 3 1 1 4 4 4 0 Sirohaem biosynthesis protein C-terminal HAUS-augmin3 PF14932.6 CRK27560.1 - 2.5 7.6 12.1 11 5.6 11.2 2.1 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 Fib_alpha PF08702.10 CRK27560.1 - 2.7 8.2 14.7 0.62 10.2 1.9 2.9 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Exonuc_VII_L PF02601.15 CRK27560.1 - 4.9 6.6 12.8 20 4.7 12.8 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit Fzo_mitofusin PF04799.13 CRK27560.1 - 5.1 6.6 8.3 0.95 9.0 2.5 2.5 1 1 2 3 3 3 0 fzo-like conserved region DUF3782 PF12644.7 CRK27560.1 - 5.1 7.3 6.3 3.3 7.9 0.3 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3782) Prominin PF05478.11 CRK27560.1 - 8.7 4.2 9.9 11 3.8 8.8 1.6 1 1 0 1 1 1 0 Prominin ERCC4 PF02732.15 CRK27563.1 - 5.1e-19 69.0 0.0 8.4e-19 68.3 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain DUF2953 PF11167.8 CRK27564.1 - 0.083 13.0 1.2 0.13 12.3 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2953) CorA PF01544.18 CRK27567.1 - 5.3e-21 75.2 4.8 4.3e-10 39.4 1.4 2.2 1 1 1 2 2 2 2 CorA-like Mg2+ transporter protein DDE_Tnp_ISL3 PF01610.17 CRK27567.1 - 1e-06 28.7 1.9 0.012 15.4 0.2 2.2 2 0 0 2 2 2 2 Transposase Ribosomal_L17 PF01196.19 CRK27567.1 - 0.00047 21.0 1.0 2 9.4 0.1 2.7 2 0 0 2 2 2 2 Ribosomal protein L17 DNA_repr_REX1B PF14966.6 CRK27567.1 - 0.01 16.5 1.3 14 6.5 0.0 3.2 3 0 0 3 3 3 0 DNA repair REX1-B SapB_1 PF05184.15 CRK27567.1 - 0.025 14.6 3.0 5 7.2 0.2 2.7 2 0 0 2 2 2 0 Saposin-like type B, region 1 Colicin_V PF02674.16 CRK27567.1 - 0.065 13.2 0.1 0.71 9.8 0.1 2.1 2 0 0 2 2 2 0 Colicin V production protein DnaB_bind PF10410.9 CRK27567.1 - 0.066 13.4 4.9 5.3 7.3 0.3 3.0 2 1 0 2 2 2 0 DnaB-helicase binding domain of primase partial_CstF PF15861.5 CRK27567.1 - 0.15 11.9 4.4 8 6.3 0.4 2.7 2 0 0 2 2 2 0 Partial cleavage stimulation factor domain L1R_F9L PF02442.17 CRK27567.1 - 0.23 11.3 0.8 23 4.8 0.1 2.2 2 0 0 2 2 2 0 Lipid membrane protein of large eukaryotic DNA viruses Pox_A3L PF05288.11 CRK27567.1 - 0.37 10.8 1.8 39 4.3 0.1 3.0 2 0 0 2 2 2 0 Poxvirus A3L Protein ApoL PF05461.11 CRK27567.1 - 0.53 9.6 8.9 3.4 6.9 1.3 2.5 2 0 0 2 2 2 0 Apolipoprotein L PhetRS_B1 PF18262.1 CRK27567.1 - 0.79 10.0 3.2 38 4.6 0.2 2.8 2 0 0 2 2 2 0 Phe-tRNA synthetase beta subunit B1 domain DUF5344 PF17279.2 CRK27567.1 - 1.2 9.7 9.5 12 6.5 0.1 3.7 4 0 0 4 4 4 0 Family of unknown function (DUF5344) GCIP PF13324.6 CRK27567.1 - 6.2 6.4 17.0 20 4.7 4.4 3.3 2 2 0 2 2 2 0 Grap2 and cyclin-D-interacting CdvA PF18822.1 CRK27567.1 - 6.5 6.6 8.3 16 5.4 0.1 3.4 4 1 0 4 4 3 0 CdvA-like coiled-coil domain Pox_A_type_inc PF04508.12 CRK27569.1 - 3 7.9 7.1 11 6.1 0.0 4.4 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat Kelch_4 PF13418.6 CRK27570.1 - 2.3e-30 104.4 10.8 2.3e-06 27.5 0.0 6.4 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_1 PF01344.25 CRK27570.1 - 1.1e-28 98.5 7.6 3.6e-12 45.7 0.4 5.8 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 CRK27570.1 - 2e-26 91.3 5.3 1.4e-09 37.9 0.6 6.4 5 1 1 6 6 6 5 Kelch motif Kelch_5 PF13854.6 CRK27570.1 - 1.6e-24 85.4 10.1 1.1e-07 31.6 0.3 6.5 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.6 CRK27570.1 - 5.5e-23 80.7 18.3 2.1e-06 27.9 0.1 6.2 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.15 CRK27570.1 - 6.4e-19 67.1 9.6 2e-06 27.6 0.3 6.2 6 1 0 6 6 6 5 Kelch motif DivIC PF04977.15 CRK27570.1 - 0.024 14.4 0.7 0.024 14.4 0.7 9.6 9 2 3 12 12 12 0 Septum formation initiator tRNA-synt_2 PF00152.20 CRK27572.1 - 2.4e-27 95.8 0.0 2.6e-27 95.7 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF4360 PF14273.6 CRK27573.1 - 2.2e-27 96.1 0.2 2.5e-27 95.9 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Ferric_reduct PF01794.19 CRK27575.1 - 9.2e-23 80.7 17.1 9.2e-23 80.7 17.1 2.4 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 CRK27575.1 - 4.5e-10 39.6 0.1 1.8e-06 28.0 0.3 2.5 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_6 PF08030.12 CRK27575.1 - 1.4e-08 35.0 0.0 0.00058 20.0 0.0 2.3 1 1 0 2 2 2 2 Ferric reductase NAD binding domain DUF4079 PF13301.6 CRK27575.1 - 1.5 9.0 12.7 7.1 6.8 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4079) DUF3094 PF11293.8 CRK27575.1 - 4.6 7.0 6.5 4.4 7.1 1.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) GFA PF04828.14 CRK27576.1 - 1.9e-11 44.1 0.3 1.9e-11 44.1 0.3 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme PTR2 PF00854.21 CRK27578.1 - 1.5e-77 261.1 11.2 2.1e-77 260.6 10.5 1.5 2 0 0 2 2 2 1 POT family Oxidored_FMN PF00724.20 CRK27580.1 - 1.2e-96 324.0 0.0 1.4e-96 323.8 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.24 CRK27580.1 - 0.021 14.2 0.0 3 7.2 0.0 2.4 1 1 1 2 2 2 0 Xylose isomerase-like TIM barrel F-box PF00646.33 CRK27581.1 - 0.0001 22.1 4.3 0.0045 16.8 0.0 3.9 4 0 0 4 4 4 1 F-box domain F-box-like PF12937.7 CRK27581.1 - 0.037 13.9 0.1 0.037 13.9 0.1 4.0 3 2 0 3 3 3 0 F-box-like F-box_4 PF15966.5 CRK27581.1 - 0.15 12.0 1.0 0.37 10.7 0.3 2.1 2 1 0 2 2 2 0 F-box adh_short PF00106.25 CRK27584.1 - 2.4e-18 66.3 0.0 4.5e-13 49.1 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CRK27584.1 - 1.3e-07 31.4 0.0 1.1e-06 28.4 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK27584.1 - 4.6e-06 26.7 0.3 8e-06 25.9 0.3 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CRK27584.1 - 0.016 14.7 0.0 0.038 13.5 0.1 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Thi4 PF01946.17 CRK27585.1 - 1.8e-113 377.6 0.1 2.2e-113 377.3 0.1 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 CRK27585.1 - 2.3e-08 34.0 3.3 3.2e-07 30.3 1.4 2.1 1 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CRK27585.1 - 4.2e-06 26.1 2.8 0.00021 20.5 0.6 2.6 2 1 1 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.6 CRK27585.1 - 8.3e-06 25.9 1.3 2.2e-05 24.6 0.5 2.2 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 CRK27585.1 - 2.8e-05 23.4 0.4 3.4e-05 23.1 0.4 1.4 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 CRK27585.1 - 6.1e-05 22.4 0.0 7.9e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CRK27585.1 - 0.00018 21.5 0.0 0.00041 20.4 0.0 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 CRK27585.1 - 0.004 16.6 0.4 0.0054 16.1 0.4 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 CRK27585.1 - 0.012 14.8 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CRK27585.1 - 0.024 13.3 0.7 0.035 12.8 0.7 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 CRK27585.1 - 0.025 13.8 0.0 0.036 13.3 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 CRK27585.1 - 0.074 12.1 0.2 0.19 10.8 0.2 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 CRK27585.1 - 0.11 11.3 0.3 0.16 10.8 0.3 1.1 1 0 0 1 1 1 0 Tryptophan halogenase K_oxygenase PF13434.6 CRK27585.1 - 0.22 10.6 0.0 0.33 10.0 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) zf-MYND PF01753.18 CRK27588.1 - 7.2e-10 38.8 14.2 1.2e-09 38.1 14.2 1.4 1 0 0 1 1 1 1 MYND finger SLT PF01464.20 CRK27588.1 - 0.053 13.2 0.0 0.089 12.5 0.0 1.3 1 0 0 1 1 1 0 Transglycosylase SLT domain zf-C6H2 PF15801.5 CRK27588.1 - 6.5 7.2 9.8 12 6.3 9.8 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding FAD_binding_3 PF01494.19 CRK27590.1 - 2.9e-10 40.0 0.0 1.1e-06 28.2 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 CRK27590.1 - 3.2e-05 23.3 0.0 7.7e-05 22.1 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CRK27590.1 - 5.2e-05 23.4 0.0 5.2e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CRK27590.1 - 0.0027 17.4 0.0 0.0054 16.3 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 CRK27590.1 - 0.0046 15.7 0.0 0.007 15.1 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 CRK27590.1 - 0.0068 15.5 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 CRK27590.1 - 0.0081 16.7 0.1 0.022 15.3 0.0 1.8 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 CRK27590.1 - 0.01 15.1 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 CRK27590.1 - 0.017 14.5 0.1 0.049 13.0 0.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase SE PF08491.10 CRK27590.1 - 0.024 13.7 0.0 0.04 13.0 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase 3HCDH_N PF02737.18 CRK27590.1 - 0.037 13.9 0.0 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 CRK27590.1 - 0.15 11.1 0.0 0.31 10.1 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain Peptidase_M24 PF00557.24 CRK27592.1 - 1.6e-46 158.6 0.0 2.1e-46 158.3 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 CRK27592.1 - 2e-21 76.0 8.3 3.7e-21 75.2 8.3 1.5 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 CRK27592.1 - 0.00044 20.3 4.9 0.00044 20.3 4.9 2.2 2 0 0 2 2 2 1 MYND finger WD40 PF00400.32 CRK27594.1 - 3.5e-26 90.9 7.6 1.5e-05 25.6 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK27594.1 - 1.2e-10 41.6 0.1 0.0027 18.0 0.0 3.6 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CRK27594.1 - 0.0065 15.5 0.5 2.7 6.9 0.0 3.1 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CRK27594.1 - 0.0079 14.9 0.7 0.56 8.8 0.0 2.6 1 1 2 3 3 3 2 Nucleoporin Nup120/160 eIF2A PF08662.11 CRK27594.1 - 0.01 15.7 0.5 4.6 7.1 0.0 3.0 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 CRK27594.1 - 0.025 13.1 0.1 0.15 10.5 0.1 2.3 2 1 1 3 3 3 0 Cytochrome D1 heme domain Arginase PF00491.21 CRK27596.1 - 6.9e-64 216.0 0.4 2.4e-63 214.3 0.4 1.7 1 1 0 1 1 1 1 Arginase family UPF0489 PF12640.7 CRK27596.1 - 0.18 12.0 0.4 0.3 11.3 0.4 1.3 1 0 0 1 1 1 0 UPF0489 domain Fungal_trans PF04082.18 CRK27598.1 - 2.7e-10 39.7 0.7 4.5e-10 39.0 0.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK27598.1 - 1.5e-05 25.0 7.1 2.5e-05 24.3 7.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Helo_like_N PF17111.5 CRK27600.1 - 1.9e-11 43.8 0.0 3.1e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins SET PF00856.28 CRK27600.1 - 1.4e-06 28.8 0.0 9.9e-06 26.0 0.0 2.5 1 1 0 1 1 1 1 SET domain GDP_Man_Dehyd PF16363.5 CRK27604.1 - 0.00028 20.4 0.0 0.00031 20.3 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 CRK27604.1 - 0.00029 20.5 0.3 0.00034 20.2 0.3 1.0 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 CRK27604.1 - 0.00049 19.6 0.1 0.00052 19.5 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 CRK27604.1 - 0.04 13.4 0.1 0.04 13.4 0.1 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Zn_clus PF00172.18 CRK27608.1 - 3.9e-09 36.5 14.0 3.9e-09 36.5 14.0 1.4 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HA2 PF04408.23 CRK27611.1 - 3.3e-10 40.2 0.2 4.4e-10 39.8 0.2 1.4 1 1 0 1 1 1 1 Helicase associated domain (HA2) eIF-3c_N PF05470.12 CRK27612.1 - 9.3e-21 73.8 9.4 9.5e-21 73.7 9.4 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus RNA_pol_Rpo13 PF12136.8 CRK27612.1 - 0.056 13.4 1.5 0.11 12.4 1.5 1.5 1 0 0 1 1 1 0 RNA polymerase Rpo13 subunit HTH domain PIN_2 PF10130.9 CRK27612.1 - 0.068 13.4 0.8 0.08 13.2 0.8 1.2 1 0 0 1 1 1 0 PIN domain Mis14 PF08641.12 CRK27612.1 - 0.073 13.4 6.1 0.17 12.2 5.7 1.8 1 1 0 1 1 1 0 Kinetochore protein Mis14 like Dynactin_p22 PF07426.11 CRK27612.1 - 0.091 12.6 4.0 0.12 12.3 2.0 1.9 1 1 1 2 2 2 0 Dynactin subunit p22 CbiG_C PF01890.16 CRK27612.1 - 0.1 13.2 0.8 0.13 12.8 0.8 1.1 1 0 0 1 1 1 0 Cobalamin synthesis G C-terminus DUF2362 PF10154.9 CRK27612.1 - 0.14 11.1 4.8 0.15 10.9 4.8 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) RasGAP_C PF03836.15 CRK27612.1 - 0.14 12.3 4.4 0.12 12.5 0.8 2.0 1 1 1 2 2 2 0 RasGAP C-terminus FKBP_N PF01346.18 CRK27612.1 - 1.5 9.9 7.6 2.9 8.9 7.6 1.5 1 1 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase TMPIT PF07851.13 CRK27612.1 - 2.8 7.1 5.0 3.3 6.9 5.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein Nup54_57_C PF18570.1 CRK27612.1 - 7.1 6.3 7.8 0.96 9.1 2.5 2.2 2 0 0 2 2 2 0 NUP57/Nup54 C-terminal domain RabGAP-TBC PF00566.18 CRK27613.1 - 3.4e-17 62.8 0.0 1.4e-16 60.8 0.0 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Myb_DNA-binding PF00249.31 CRK27614.1 - 0.0025 18.0 0.2 0.012 15.8 0.0 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain Helicase_C PF00271.31 CRK27615.1 - 4.2e-15 56.0 0.1 2.6e-14 53.5 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CRK27615.1 - 2.1e-12 47.4 0.0 5.5e-11 42.8 0.1 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CRK27615.1 - 3.4e-07 30.2 0.1 2.6e-05 24.0 0.1 2.6 2 1 0 2 2 2 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 CRK27615.1 - 0.00056 19.2 0.0 0.00098 18.4 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase KH_1 PF00013.29 CRK27616.1 - 1.4e-29 101.7 4.1 1.6e-07 31.1 0.0 7.2 7 0 0 7 7 7 6 KH domain HAD_2 PF13419.6 CRK27618.1 - 2.7e-10 40.6 0.0 4.7e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CRK27618.1 - 6.1e-09 36.5 0.0 1.2e-08 35.6 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CRK27618.1 - 3.6e-05 23.7 0.0 7.9e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like G_path_suppress PF15991.5 CRK27618.1 - 0.081 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor Med21 PF11221.8 CRK27619.1 - 1.1e-46 158.7 6.5 1.2e-46 158.6 6.5 1.0 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Med9 PF07544.13 CRK27619.1 - 0.0075 16.3 0.4 0.0075 16.3 0.4 2.6 2 1 1 3 3 3 1 RNA polymerase II transcription mediator complex subunit 9 GAS PF13851.6 CRK27619.1 - 0.0078 15.6 3.6 1.6 8.1 1.7 2.1 2 0 0 2 2 2 2 Growth-arrest specific micro-tubule binding Spore_III_AB PF09548.10 CRK27619.1 - 0.058 13.5 1.8 0.076 13.1 1.8 1.3 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) HAUS-augmin3 PF14932.6 CRK27619.1 - 0.52 9.8 6.3 1.1 8.7 2.3 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 COPI_assoc PF08507.10 CRK27620.1 - 1.9e-32 112.1 7.9 2.6e-32 111.6 7.9 1.2 1 0 0 1 1 1 1 COPI associated protein GATA PF00320.27 CRK27620.1 - 1.3e-30 104.7 19.2 2.3e-16 59.1 4.5 2.4 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 CRK27620.1 - 3.3e-07 29.7 5.4 0.0043 16.5 0.3 2.6 2 0 0 2 2 2 2 TFIIB zinc-binding ArfGap PF01412.18 CRK27620.1 - 0.00018 21.5 1.8 0.52 10.4 0.1 2.3 2 0 0 2 2 2 2 Putative GTPase activating protein for Arf Zn-ribbon_8 PF09723.10 CRK27620.1 - 0.00099 19.2 10.1 0.077 13.1 0.2 2.9 3 0 0 3 3 2 2 Zinc ribbon domain Auto_anti-p27 PF06677.12 CRK27620.1 - 0.001 19.2 6.5 0.18 12.0 1.0 2.4 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) OrfB_Zn_ribbon PF07282.11 CRK27620.1 - 0.001 18.9 7.2 0.04 13.9 1.3 2.7 2 0 0 2 2 2 2 Putative transposase DNA-binding domain eIF-5_eIF-2B PF01873.17 CRK27620.1 - 0.03 14.2 6.4 0.84 9.5 0.8 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 zf-RRN7 PF11781.8 CRK27620.1 - 0.032 13.9 10.2 0.061 13.0 0.6 3.1 2 1 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Prim_Zn_Ribbon PF08273.12 CRK27620.1 - 0.033 14.5 12.0 0.11 12.8 0.5 3.5 2 1 1 3 3 3 0 Zinc-binding domain of primase-helicase Rubredoxin_2 PF18073.1 CRK27620.1 - 0.33 10.7 10.2 9.7 6.0 0.2 4.7 4 0 0 4 4 4 0 Rubredoxin metal binding domain zf-ribbon_3 PF13248.6 CRK27620.1 - 0.74 9.3 10.7 9.1 5.8 0.1 4.3 4 0 0 4 4 4 0 zinc-ribbon domain Jiv90 PF14901.6 CRK27620.1 - 0.86 9.8 3.8 1.8 8.7 0.4 2.3 2 0 0 2 2 2 0 Cleavage inducing molecular chaperone Cg6151-P PF10233.9 CRK27620.1 - 1.5 9.2 9.7 2.6 8.4 9.7 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein CG6151-P ADK_lid PF05191.14 CRK27620.1 - 1.8 8.6 7.4 1.5 8.9 0.6 3.5 3 0 0 3 3 3 0 Adenylate kinase, active site lid DZR PF12773.7 CRK27620.1 - 1.9 8.6 15.1 5.8 7.0 1.6 3.2 1 1 2 3 3 3 0 Double zinc ribbon A2L_zn_ribbon PF08792.10 CRK27620.1 - 2.3 8.1 10.2 74 3.2 0.2 4.3 3 1 0 3 3 3 0 A2L zinc ribbon domain Presenilin PF01080.17 CRK27621.1 - 5.3 5.7 4.8 0.68 8.6 0.5 1.6 2 0 0 2 2 2 0 Presenilin SAP PF02037.27 CRK27622.1 - 7.7e-11 41.5 0.2 1.3e-10 40.8 0.2 1.4 1 0 0 1 1 1 1 SAP domain CPSase_sm_chain PF00988.22 CRK27623.1 - 2.8e-29 101.5 0.0 5.3e-29 100.6 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 CRK27623.1 - 7.9e-22 77.9 0.0 1e-21 77.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 CRK27623.1 - 0.0012 18.6 0.1 0.0032 17.2 0.1 1.7 1 1 0 1 1 1 1 Peptidase C26 ETF PF01012.21 CRK27624.1 - 4.2e-44 150.6 0.4 6.1e-44 150.1 0.4 1.2 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Coa1 PF08695.10 CRK27625.1 - 6.7e-43 145.2 0.0 9.3e-43 144.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Ribosomal_L3 PF00297.22 CRK27626.1 - 1.1e-15 57.5 3.9 2.1e-12 46.7 3.9 2.2 1 1 0 1 1 1 1 Ribosomal protein L3 Glyco_hydro_18 PF00704.28 CRK27627.1 - 8e-49 167.0 0.8 1.2e-48 166.4 0.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 CRK27627.1 - 4.4e-06 27.1 10.5 4.4e-06 27.1 10.5 2.7 2 0 0 2 2 2 1 Chitin recognition protein DUF373 PF04123.13 CRK27627.1 - 0.042 13.3 0.3 0.07 12.6 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) G6PD_N PF00479.22 CRK27629.1 - 5.3e-18 66.3 0.0 7.4e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain G6PD_C PF02781.16 CRK27629.1 - 7.9e-15 54.8 0.0 9.5e-15 54.5 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain Pkinase PF00069.25 CRK27632.1 - 8.1e-75 251.6 0.0 1.1e-74 251.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK27632.1 - 1.8e-30 106.1 0.0 3.8e-22 78.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CRK27632.1 - 2e-06 27.3 0.1 1.3 8.3 0.0 3.2 3 0 0 3 3 3 3 Kinase-like Pkinase_fungal PF17667.1 CRK27632.1 - 0.012 14.4 0.0 0.022 13.5 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 CRK27632.1 - 0.017 14.5 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CRK27632.1 - 0.025 14.5 0.0 0.87 9.5 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family DASH_Dad3 PF08656.10 CRK27633.1 - 1.4e-32 111.5 0.5 1.9e-32 111.2 0.5 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad3 MetOD2 PF18548.1 CRK27633.1 - 0.11 12.6 0.1 0.18 11.9 0.1 1.3 1 0 0 1 1 1 0 Metanogen output domain 2 Ribosomal_S5_C PF03719.15 CRK27634.1 - 1e-20 72.9 0.4 4.5e-20 70.9 0.0 2.2 3 0 0 3 3 3 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 CRK27634.1 - 1e-15 57.5 2.0 1.4e-15 57.0 0.2 2.0 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain COX2_TM PF02790.15 CRK27635.1 - 0.014 15.5 0.0 0.015 15.4 0.0 1.1 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane domain DUF1206 PF06724.11 CRK27635.1 - 0.032 14.3 0.3 0.04 14.0 0.3 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) DUF1180 PF06679.12 CRK27635.1 - 0.13 12.6 0.0 0.15 12.5 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) SLAC1 PF03595.17 CRK27638.1 - 5e-37 127.9 22.2 6.7e-37 127.5 22.2 1.1 1 0 0 1 1 1 1 Voltage-dependent anion channel COG5 PF10392.9 CRK27638.1 - 0.00086 19.5 0.3 0.00086 19.5 0.3 2.3 3 0 0 3 3 3 1 Golgi transport complex subunit 5 Noggin PF05806.12 CRK27638.1 - 0.052 13.5 0.2 0.16 11.9 0.1 1.7 2 0 0 2 2 2 0 Noggin Sds3 PF08598.11 CRK27639.1 - 6.5e-24 85.1 4.6 8.9e-24 84.7 4.6 1.3 1 0 0 1 1 1 1 Sds3-like Abp2 PF09441.10 CRK27641.1 - 5.7e-83 277.1 0.0 8.9e-83 276.5 0.0 1.3 1 0 0 1 1 1 1 ARS binding protein 2 MS_channel PF00924.18 CRK27642.1 - 5.5e-20 71.8 2.6 9.8e-20 71.0 2.6 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_5 PF13202.6 CRK27642.1 - 0.0039 16.6 0.1 0.013 14.9 0.1 1.9 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 CRK27642.1 - 0.02 14.4 0.1 0.065 12.8 0.1 1.9 1 0 0 1 1 1 0 EF hand E1-E2_ATPase PF00122.20 CRK27642.1 - 2.5 7.6 5.4 1.2 8.6 0.6 2.3 2 0 0 2 2 2 0 E1-E2 ATPase Glyco_hydro_61 PF03443.14 CRK27643.1 - 1.3e-31 110.2 0.1 2e-31 109.6 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DLH PF01738.18 CRK27643.1 - 3.1e-21 75.9 0.0 7.9e-21 74.6 0.0 1.6 2 0 0 2 2 2 1 Dienelactone hydrolase family Ribosomal_S6e PF01092.19 CRK27644.1 - 5.3e-57 191.2 0.4 1.1e-56 190.2 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S6e DUF913 PF06025.12 CRK27645.1 - 4.1e-130 434.0 6.8 1.9e-129 431.8 0.0 3.6 3 0 0 3 3 3 1 Domain of Unknown Function (DUF913) DUF908 PF06012.12 CRK27645.1 - 5.4e-127 424.1 0.7 5.4e-127 424.1 0.7 2.5 2 0 0 2 2 2 1 Domain of Unknown Function (DUF908) HECT PF00632.25 CRK27645.1 - 2.8e-93 312.8 0.1 6.3e-93 311.6 0.1 1.6 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) UBM PF14377.6 CRK27645.1 - 6.1e-17 60.5 10.5 2.9e-08 32.9 3.6 3.0 2 0 0 2 2 2 2 Ubiquitin binding region FleQ PF06490.11 CRK27645.1 - 0.13 12.7 0.0 9.3 6.7 0.0 3.2 2 0 0 2 2 2 0 Flagellar regulatory protein FleQ RNA12 PF10443.9 CRK27646.1 - 3.1e-165 550.2 1.4 5.5e-165 549.4 1.4 1.4 1 0 0 1 1 1 1 RNA12 protein RRM_1 PF00076.22 CRK27646.1 - 1.1e-06 28.3 0.0 2.3e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATPase_2 PF01637.18 CRK27646.1 - 4.6e-06 26.7 0.6 0.0054 16.7 0.0 2.5 2 0 0 2 2 2 2 ATPase domain predominantly from Archaea DUF2487 PF10673.9 CRK27646.1 - 0.0056 16.7 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2487) AAA_16 PF13191.6 CRK27646.1 - 0.054 13.9 0.0 0.21 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain CinA PF02464.17 CRK27648.1 - 0.062 12.9 0.0 0.075 12.6 0.0 1.1 1 0 0 1 1 1 0 Competence-damaged protein ADH_zinc_N PF00107.26 CRK27651.1 - 7.5e-08 32.4 1.2 9.8e-08 32.0 0.2 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CRK27651.1 - 0.00029 20.7 0.0 0.0005 19.9 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 CRK27651.1 - 0.028 15.4 0.0 0.062 14.4 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase PALP PF00291.25 CRK27651.1 - 0.041 13.3 0.1 0.058 12.8 0.1 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme DUF2374 PF09574.10 CRK27651.1 - 0.08 12.8 0.8 0.16 11.8 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (Duf2374) Peptidase_M14 PF00246.24 CRK27652.1 - 7.2e-32 111.3 0.0 9.7e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase RVT_1 PF00078.27 CRK27653.1 - 0.00062 19.3 0.0 0.0013 18.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) F-box_4 PF15966.5 CRK27653.1 - 0.19 11.6 0.8 0.54 10.2 0.2 2.0 2 0 0 2 2 2 0 F-box Dynamin_M PF01031.20 CRK27654.1 - 2.7e-18 66.2 0.4 2.2e-08 33.7 0.1 2.3 2 0 0 2 2 2 2 Dynamin central region Dynamin_N PF00350.23 CRK27654.1 - 9.9e-18 64.8 0.0 5.7e-17 62.3 0.0 2.3 2 1 0 2 2 2 1 Dynamin family GED PF02212.18 CRK27654.1 - 8.1e-06 25.9 0.1 2.3e-05 24.5 0.1 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain Nuc_sug_transp PF04142.15 CRK27655.1 - 5.2e-94 314.9 10.9 8.2e-94 314.3 10.9 1.3 1 1 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 CRK27655.1 - 6.5e-07 28.8 6.0 1.8e-06 27.4 2.3 2.1 2 0 0 2 2 2 1 UAA transporter family EamA PF00892.20 CRK27655.1 - 6.6e-06 26.3 23.2 0.00097 19.3 2.7 2.3 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 CRK27655.1 - 4.6e-05 22.9 11.9 0.0018 17.7 3.9 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family Sec63 PF02889.16 CRK27656.1 - 1.4e-05 24.4 0.0 2.3e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DUF4332 PF14229.6 CRK27656.1 - 0.0036 17.5 0.7 0.018 15.2 0.0 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4332) TfoX_C PF04994.13 CRK27656.1 - 0.007 16.4 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 TfoX C-terminal domain HHH_5 PF14520.6 CRK27656.1 - 0.097 13.3 0.0 0.33 11.6 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix domain DCB PF16213.5 CRK27657.1 - 4.7e-48 163.2 7.2 6.5e-47 159.5 6.2 2.8 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 CRK27657.1 - 3.3e-42 144.1 4.6 3.8e-41 140.6 0.3 3.8 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Mon2_C PF16206.5 CRK27657.1 - 8.4e-28 97.0 1.8 1e-22 80.2 0.8 3.6 3 1 0 3 3 3 3 C-terminal region of Mon2 protein DUF1981 PF09324.10 CRK27657.1 - 5e-05 23.1 0.3 0.0021 17.9 0.0 3.6 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) Band_7 PF01145.25 CRK27658.1 - 2e-30 106.1 0.4 4.1e-30 105.1 0.4 1.5 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_C PF16200.5 CRK27658.1 - 7e-24 83.7 1.3 1.9e-23 82.3 1.3 1.8 1 0 0 1 1 1 1 C-terminal region of band_7 Pox_A11 PF05061.13 CRK27658.1 - 0.0085 15.4 0.2 0.013 14.8 0.2 1.3 1 0 0 1 1 1 1 Poxvirus A11 Protein Band_7_1 PF13421.6 CRK27658.1 - 0.053 13.2 0.0 0.099 12.3 0.0 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family GSH-S_N PF02951.14 CRK27658.1 - 0.088 12.9 0.1 0.17 12.0 0.1 1.6 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, N-terminal domain Fungal_trans PF04082.18 CRK27660.1 - 1.8e-17 63.3 0.0 3.1e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK27660.1 - 7.3e-07 29.2 16.5 1.2e-06 28.5 16.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transp_cyt_pur PF02133.15 CRK27661.1 - 6.2e-95 318.6 31.5 3e-94 316.3 31.5 1.8 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Amidase PF01425.21 CRK27662.1 - 4.3e-78 263.3 0.0 5.3e-78 263.0 0.0 1.1 1 0 0 1 1 1 1 Amidase Isochorismatase PF00857.20 CRK27662.1 - 3.9e-38 131.4 0.0 8e-38 130.3 0.0 1.6 1 0 0 1 1 1 1 Isochorismatase family ABM PF03992.16 CRK27663.1 - 0.042 14.0 0.7 0.078 13.1 0.1 1.7 2 0 0 2 2 2 0 Antibiotic biosynthesis monooxygenase SbcCD_C PF13558.6 CRK27664.1 - 0.003 17.7 0.2 0.0072 16.5 0.0 1.7 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.19 CRK27664.1 - 0.0041 16.6 0.0 0.0043 16.5 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_tran PF00005.27 CRK27664.1 - 0.057 13.9 0.2 0.085 13.4 0.2 1.2 1 0 0 1 1 1 0 ABC transporter ATP-synt_D PF01813.17 CRK27664.1 - 0.07 13.0 1.2 0.095 12.5 1.2 1.2 1 0 0 1 1 1 0 ATP synthase subunit D MIP PF00230.20 CRK27666.1 - 6.5e-29 101.3 5.3 7.5e-29 101.0 5.3 1.0 1 0 0 1 1 1 1 Major intrinsic protein DUF2368 PF10166.9 CRK27666.1 - 0.055 13.1 1.3 0.071 12.7 0.3 1.6 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2368) DAO PF01266.24 CRK27667.1 - 5.1e-54 184.2 0.1 6.9e-54 183.8 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 CRK27667.1 - 2.8e-41 140.3 0.0 4.9e-41 139.5 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 CRK27667.1 - 2.3e-09 36.9 2.8 0.00025 20.3 1.1 2.3 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 CRK27667.1 - 4.8e-07 29.5 0.8 0.00013 21.5 0.2 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CRK27667.1 - 0.00018 20.9 0.3 0.0004 19.7 0.3 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CRK27667.1 - 0.00063 19.9 0.1 0.0077 16.4 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 CRK27667.1 - 0.005 17.4 0.8 0.24 12.0 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CRK27667.1 - 0.0059 15.7 0.8 0.076 12.1 0.2 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 CRK27667.1 - 0.02 13.6 0.1 0.036 12.8 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.17 CRK27667.1 - 0.022 14.0 0.2 0.23 10.7 0.0 2.4 2 0 0 2 2 2 0 Thi4 family 3HCDH_N PF02737.18 CRK27667.1 - 0.024 14.5 0.1 0.059 13.3 0.1 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 CRK27667.1 - 0.04 13.2 0.0 0.13 11.5 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CRK27667.1 - 0.14 11.2 0.2 0.45 9.5 0.1 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein Cu-oxidase_2 PF07731.14 CRK27668.1 - 1.2e-28 99.5 3.1 6.9e-27 93.9 2.6 2.8 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 CRK27668.1 - 8.5e-15 54.8 0.6 3.6e-14 52.8 0.1 2.2 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 CRK27668.1 - 2e-05 24.7 0.0 0.00015 21.9 0.0 2.2 2 0 0 2 2 2 1 Multicopper oxidase C6 PF01681.17 CRK27669.1 - 0.1 13.1 4.8 0.28 11.8 4.8 1.7 1 0 0 1 1 1 0 C6 domain Steroid_dh PF02544.16 CRK27670.1 - 3.2e-19 69.4 0.3 6.5e-19 68.4 0.3 1.5 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 CRK27670.1 - 0.00021 20.9 0.3 0.00034 20.2 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) MINDY_DUB PF04424.13 CRK27671.1 - 9.8e-24 83.6 0.0 1.5e-23 83.0 0.0 1.3 1 0 0 1 1 1 1 MINDY deubiquitinase Peptidase_M28 PF04389.17 CRK27672.1 - 2.9e-35 121.8 0.2 4.4e-35 121.2 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 CRK27672.1 - 5.7e-08 32.7 0.0 1.1e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DUF1977 PF09320.11 CRK27673.1 - 6.6e-31 106.7 0.8 6.6e-31 106.7 0.8 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 CRK27673.1 - 2.6e-19 69.1 0.1 5.4e-19 68.1 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain Aim19 PF10315.9 CRK27674.1 - 5.6e-05 23.4 0.2 8.5e-05 22.8 0.2 1.5 1 1 0 1 1 1 1 Altered inheritance of mitochondria protein 19 Y_phosphatase2 PF03162.13 CRK27675.1 - 3.6e-45 153.5 0.0 5.6e-45 152.9 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 CRK27675.1 - 3.5e-11 43.5 0.0 2e-10 41.1 0.0 2.0 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 CRK27675.1 - 0.0023 17.5 0.0 0.0035 16.9 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 CRK27675.1 - 0.011 15.5 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Ima1_N PF09779.9 CRK27676.1 - 1.6e-35 122.9 3.1 2.7e-35 122.2 3.1 1.4 1 0 0 1 1 1 1 Ima1 N-terminal domain Casein_kappa PF00997.18 CRK27676.1 - 0.029 14.5 0.4 0.062 13.4 0.4 1.5 1 0 0 1 1 1 0 Kappa casein Gal-3-0_sulfotr PF06990.11 CRK27676.1 - 0.068 12.0 0.1 0.12 11.2 0.1 1.3 1 0 0 1 1 1 0 Galactose-3-O-sulfotransferase DUF1451 PF07295.11 CRK27676.1 - 0.23 11.5 0.1 0.5 10.4 0.1 1.5 1 0 0 1 1 1 0 Zinc-ribbon containing domain Alg14 PF08660.11 CRK27678.1 - 5.3e-47 160.0 0.0 8.2e-47 159.4 0.0 1.3 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like MRP-S25 PF13741.6 CRK27680.1 - 5.7e-44 150.4 17.9 6e-25 88.2 3.5 3.1 1 1 2 3 3 3 3 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 CRK27680.1 - 0.0017 18.6 1.3 0.0052 17.1 1.2 1.9 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S23 Olfactory_mark PF06554.12 CRK27680.1 - 0.045 13.5 0.1 0.073 12.8 0.1 1.3 1 0 0 1 1 1 0 Olfactory marker protein PPR PF01535.20 CRK27682.1 - 3.5e-20 70.8 3.2 9.5e-06 25.5 0.0 6.1 6 0 0 6 6 6 4 PPR repeat PPR_2 PF13041.6 CRK27682.1 - 1.4e-19 70.0 0.3 1.3e-05 25.3 0.0 5.5 3 1 3 6 6 6 4 PPR repeat family PPR_3 PF13812.6 CRK27682.1 - 3.1e-13 49.6 0.0 0.00065 19.7 0.0 4.5 4 0 0 4 4 4 3 Pentatricopeptide repeat domain PPR_1 PF12854.7 CRK27682.1 - 5.7e-13 48.3 0.2 0.0014 18.3 0.1 4.1 4 0 0 4 4 4 3 PPR repeat PPR_long PF17177.4 CRK27682.1 - 2.3e-05 23.9 0.0 0.016 14.6 0.0 2.9 1 1 2 3 3 3 3 Pentacotripeptide-repeat region of PRORP COX7C PF02935.16 CRK27684.1 - 3.1e-21 75.4 5.5 4.2e-21 75.0 5.5 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc rRNA_proc-arch PF13234.6 CRK27685.1 - 1.1e-84 284.6 0.0 2.9e-84 283.2 0.0 1.8 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 CRK27685.1 - 2.1e-48 164.1 1.9 1.1e-47 161.8 2.3 2.0 3 0 0 3 3 3 1 DSHCT (NUC185) domain DEAD PF00270.29 CRK27685.1 - 1.1e-09 38.3 0.0 3.2e-09 36.8 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CRK27685.1 - 3.7e-08 33.7 0.0 1.1e-07 32.1 0.0 1.9 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CRK27685.1 - 0.0051 16.8 0.0 0.017 15.2 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 CRK27685.1 - 0.066 12.3 0.0 0.16 11.0 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF2407_C PF13373.6 CRK27687.1 - 8.7e-37 126.4 0.2 1.2e-36 125.9 0.2 1.2 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.9 CRK27687.1 - 4.6e-30 104.2 0.0 7.6e-30 103.5 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 CRK27687.1 - 8.1e-06 25.5 0.0 2.9e-05 23.7 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD_2 PF13881.6 CRK27687.1 - 0.0014 18.7 0.0 0.0024 17.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Aminotran_1_2 PF00155.21 CRK27689.1 - 3.2e-69 233.8 0.0 3.7e-69 233.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 CRK27689.1 - 0.00036 19.9 0.0 0.00053 19.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 CRK27689.1 - 0.00096 18.6 0.0 0.0027 17.1 0.0 1.7 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 CRK27689.1 - 0.0018 16.9 0.0 0.0034 16.0 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 CRK27689.1 - 0.02 13.9 0.0 0.042 12.8 0.0 1.5 1 1 0 1 1 1 0 Aminotransferase class-V Foie-gras_1 PF11817.8 CRK27689.1 - 0.18 11.3 0.0 0.34 10.5 0.0 1.4 1 0 0 1 1 1 0 Foie gras liver health family 1 ORC6 PF05460.13 CRK27691.1 - 0.00018 20.9 0.7 0.00027 20.3 0.7 1.3 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) DUF4750 PF15938.5 CRK27691.1 - 0.00045 19.8 1.3 0.85 9.3 0.1 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4750) DUF4234 PF14018.6 CRK27691.1 - 0.0013 18.8 0.1 2.3 8.4 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4234) PP1_bind PF15276.6 CRK27691.1 - 0.0069 16.7 1.0 0.0069 16.7 1.0 2.2 2 0 0 2 2 2 1 Protein phosphatase 1 binding Adeno_E3_14_5 PF04834.12 CRK27691.1 - 0.0092 16.5 1.8 2.3 8.8 0.1 2.5 1 1 1 2 2 2 2 Early E3 14.5 kDa protein Sigma70_r4 PF04545.16 CRK27691.1 - 0.075 12.6 0.0 16 5.1 0.0 2.3 2 0 0 2 2 2 0 Sigma-70, region 4 Pneumo_att_G PF05539.11 CRK27691.1 - 0.24 11.0 8.3 0.36 10.4 8.3 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Hemerythrin PF01814.23 CRK27692.1 - 1.5e-12 48.3 1.5 2.4e-12 47.6 1.5 1.4 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain CTD_bind PF04818.13 CRK27692.1 - 0.19 12.6 1.0 1.6 9.6 0.4 2.7 1 1 1 2 2 2 0 RNA polymerase II-binding domain. Melibiase PF02065.18 CRK27694.1 - 7.3e-142 472.4 0.0 9.4e-142 472.0 0.0 1.1 1 0 0 1 1 1 1 Melibiase Glyco_hydro_36N PF16875.5 CRK27694.1 - 3.6e-81 272.4 0.0 5.5e-81 271.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 N-terminal domain Glyco_hydro_36C PF16874.5 CRK27694.1 - 1e-20 74.0 0.0 2e-20 73.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 C-terminal domain GHL10 PF02638.15 CRK27694.1 - 0.00013 21.2 0.0 0.00021 20.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase-like 10 Asparaginase_II PF06089.12 CRK27700.1 - 5.7e-115 383.8 2.9 6.5e-115 383.6 2.9 1.0 1 0 0 1 1 1 1 L-asparaginase II WSC PF01822.19 CRK27701.1 - 6.2e-66 218.6 44.8 1.6e-17 63.5 7.1 4.4 4 0 0 4 4 4 4 WSC domain PQQ_3 PF13570.6 CRK27701.1 - 0.0064 16.9 7.0 0.28 11.7 0.0 5.4 5 0 0 5 5 5 1 PQQ-like domain ASH PF15780.5 CRK27701.1 - 0.034 14.3 1.5 7.6 6.8 0.0 3.4 3 0 0 3 3 3 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 CRK27701.1 - 0.077 13.2 0.3 29 4.9 0.0 3.9 4 0 0 4 4 4 0 Flagellar-associated PapD-like PepSY PF03413.19 CRK27701.1 - 0.1 13.2 0.2 0.71 10.5 0.0 2.5 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain PQQ PF01011.21 CRK27701.1 - 0.16 11.9 1.0 8.8 6.5 0.0 4.0 3 0 0 3 3 3 0 PQQ enzyme repeat PQQ_2 PF13360.6 CRK27701.1 - 0.62 9.6 0.0 0.62 9.6 0.0 3.2 4 0 0 4 4 4 0 PQQ-like domain Prok-RING_1 PF14446.6 CRK27701.1 - 2.7 8.0 7.4 0.16 11.9 0.7 2.4 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 Ribonuc_L-PSP PF01042.21 CRK27702.1 - 3.5e-23 81.9 0.0 3.4e-12 46.4 0.0 2.3 2 0 0 2 2 2 2 Endoribonuclease L-PSP Git3 PF11710.8 CRK27702.1 - 6.1e-10 39.2 6.5 2.2e-09 37.4 6.5 1.9 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Dicty_CAR PF05462.11 CRK27702.1 - 1.9e-05 23.9 3.4 0.00013 21.2 1.5 2.1 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor GPR_Gpa2_C PF11970.8 CRK27702.1 - 0.00055 19.9 0.4 0.0017 18.4 0.0 1.9 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.21 CRK27702.1 - 0.026 13.8 0.2 0.037 13.4 0.2 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) C166 PF17615.2 CRK27703.1 - 5.9e-06 26.5 1.3 7.9e-06 26.1 1.3 1.1 1 0 0 1 1 1 1 Family of unknown function Oxidored_molyb PF00174.19 CRK27704.1 - 1.9e-53 180.6 0.0 4.1e-53 179.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 CRK27704.1 - 5.7e-36 123.6 0.5 5.7e-36 123.6 0.5 2.0 2 0 0 2 2 2 1 Mo-co oxidoreductase dimerisation domain NAD_binding_1 PF00175.21 CRK27704.1 - 1.6e-25 89.9 0.0 8.2e-25 87.6 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 CRK27704.1 - 1.2e-19 70.5 0.0 2.9e-08 33.9 0.0 2.5 2 0 0 2 2 2 2 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.28 CRK27704.1 - 2.9e-15 56.1 0.1 7.8e-15 54.8 0.1 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 CRK27704.1 - 0.14 12.2 0.0 4.4 7.4 0.0 2.4 2 0 0 2 2 2 0 Ferric reductase NAD binding domain OPT PF03169.15 CRK27706.1 - 5.1e-231 768.6 81.2 3.7e-116 389.2 40.1 2.0 2 0 0 2 2 2 2 OPT oligopeptide transporter protein Phage_holin_5_2 PF16079.5 CRK27706.1 - 0.0045 17.3 12.7 0.15 12.4 0.7 4.8 4 0 0 4 4 3 2 Phage holin family Hol44, in holin superfamily V RHD3 PF05879.12 CRK27706.1 - 0.022 12.9 0.5 2.8 5.9 0.1 2.2 2 0 0 2 2 2 0 Root hair defective 3 GTP-binding protein (RHD3) CrgA PF06781.12 CRK27706.1 - 0.025 14.6 2.7 6.8 6.8 0.2 3.2 2 0 0 2 2 2 0 Cell division protein CrgA Barstar PF01337.18 CRK27706.1 - 0.11 12.6 0.1 0.32 11.0 0.1 1.8 1 0 0 1 1 1 0 Barstar (barnase inhibitor) Flavoprotein PF02441.19 CRK27706.1 - 0.11 12.3 0.6 11 5.8 0.1 2.5 2 0 0 2 2 2 0 Flavoprotein E2 PF08199.11 CRK27706.1 - 0.13 12.2 0.0 28 4.8 0.0 2.5 2 0 0 2 2 2 0 Bacteriophage E2-like protein zf-UBP PF02148.19 CRK27706.1 - 0.27 11.6 2.5 21 5.5 0.2 2.4 2 0 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein DUF3493 PF11998.8 CRK27706.1 - 1.1 9.4 6.4 23 5.2 0.7 3.3 2 0 0 2 2 2 0 Low psii accumulation1 / Rep27 DUF1056 PF06341.11 CRK27706.1 - 4.4 7.7 18.6 0.99 9.8 0.2 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1056) Pga1 PF10333.9 CRK27706.1 - 6.4 6.6 5.8 17 5.3 0.7 2.3 2 0 0 2 2 2 0 GPI-Mannosyltransferase II co-activator PAF-AH_p_II PF03403.13 CRK27707.1 - 5.1e-37 127.3 0.0 8.7e-29 100.2 0.0 3.2 3 0 0 3 3 3 3 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 CRK27707.1 - 8.8e-05 21.5 0.0 0.0002 20.4 0.0 1.5 2 0 0 2 2 2 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 CRK27707.1 - 0.0077 15.3 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Hydrolase_4 PF12146.8 CRK27707.1 - 0.11 11.8 0.0 1.5 8.0 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 BRCT PF00533.26 CRK27708.1 - 9.2e-06 26.0 0.0 2.1e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 CRK27708.1 - 0.00076 19.8 0.0 0.0017 18.7 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 CRK27708.1 - 0.001 18.9 0.0 0.0022 17.8 0.0 1.6 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_3 PF18428.1 CRK27708.1 - 0.02 14.9 0.0 4.8 7.3 0.0 2.6 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain NmrA PF05368.13 CRK27709.1 - 9.2e-20 71.2 0.0 1.1e-19 70.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 CRK27709.1 - 3.4e-10 40.1 0.0 5.6e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 CRK27709.1 - 0.0067 16.9 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 CRK27709.1 - 0.057 13.7 0.0 0.094 13.0 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DDOST_48kD PF03345.14 CRK27710.1 - 6.3e-15 54.9 0.0 7.3e-15 54.7 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta CBFD_NFYB_HMF PF00808.23 CRK27711.1 - 2.2e-06 27.8 0.4 2.4e-06 27.8 0.4 1.0 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Peptidase_M14 PF00246.24 CRK27713.1 - 2.1e-72 244.4 0.0 2.5e-72 244.1 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Methyltransf_11 PF08241.12 CRK27714.1 - 2.2e-16 60.3 0.0 4.3e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK27714.1 - 9.1e-15 55.2 0.0 1.8e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK27714.1 - 4.7e-10 40.1 0.0 8.8e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK27714.1 - 1.6e-07 31.3 0.0 2.5e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CRK27714.1 - 6.7e-05 22.8 0.0 0.00021 21.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 CRK27714.1 - 0.14 11.7 0.0 0.51 9.9 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase small domain AMP_N PF05195.16 CRK27715.1 - 1e-25 89.8 0.0 2.2e-25 88.8 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Peptidase_C12 PF01088.21 CRK27715.1 - 5.5e-23 81.8 0.0 1.3e-22 80.6 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Peptidase_M24 PF00557.24 CRK27715.1 - 6.2e-15 55.5 0.4 1.1e-10 41.6 0.0 2.3 1 1 1 2 2 2 2 Metallopeptidase family M24 Sugar_tr PF00083.24 CRK27716.1 - 1.3e-27 96.8 1.5 1.6e-27 96.5 1.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK27716.1 - 3.6e-08 32.7 6.3 3.6e-08 32.7 6.3 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Gpr1_Fun34_YaaH PF01184.19 CRK27717.1 - 4.4e-30 104.8 17.2 7.1e-29 100.9 17.2 2.5 1 1 0 1 1 1 1 GPR1/FUN34/yaaH family FAD_binding_4 PF01565.23 CRK27717.1 - 3.2e-23 82.0 0.5 5.7e-23 81.2 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 CRK27717.1 - 0.0014 18.7 0.0 0.0029 17.7 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Acyl-CoA_dh_2 PF08028.11 CRK27718.1 - 1.3e-13 51.4 0.3 2.3e-13 50.6 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CRK27718.1 - 1.4e-05 25.7 0.0 2.5e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 CRK27718.1 - 2.7e-05 24.3 0.0 9.5e-05 22.5 0.0 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 CRK27718.1 - 0.033 14.4 0.1 0.073 13.3 0.0 1.7 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain Pectate_lyase PF03211.13 CRK27719.1 - 3.3e-83 278.2 6.9 4.2e-83 277.9 6.9 1.1 1 0 0 1 1 1 1 Pectate lyase MIP PF00230.20 CRK27719.1 - 6.7e-34 117.6 0.7 9.5e-34 117.1 0.7 1.1 1 0 0 1 1 1 1 Major intrinsic protein Sugar_tr PF00083.24 CRK27720.1 - 6.7e-119 397.7 21.0 7.7e-119 397.5 21.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK27720.1 - 3.3e-25 88.8 59.4 8.3e-23 80.9 30.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 CRK27720.1 - 0.0019 16.8 0.1 0.0019 16.8 0.1 3.9 3 1 1 4 4 4 1 MFS/sugar transport protein DUF1772 PF08592.11 CRK27720.1 - 1.5 9.2 13.7 18 5.6 1.0 3.8 2 1 1 3 3 3 0 Domain of unknown function (DUF1772) DUF3602 PF12223.8 CRK27721.1 - 0.021 15.4 2.2 0.045 14.4 2.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3602) ANAPC4 PF12896.7 CRK27723.1 - 9.6e-25 87.3 0.0 1.1e-24 87.1 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 WD40 PF00400.32 CRK27725.1 - 0.0085 16.9 0.1 1.3 10.1 0.1 3.5 3 0 0 3 3 3 1 WD domain, G-beta repeat Abhydrolase_6 PF12697.7 CRK27727.1 - 1.1e-12 49.1 7.1 2.4e-12 48.0 7.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CRK27727.1 - 1.2e-05 24.7 0.3 0.012 14.9 0.0 2.7 3 0 0 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CRK27727.1 - 0.00034 20.4 0.1 0.00062 19.5 0.1 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold AAA_22 PF13401.6 CRK27727.1 - 0.0019 18.4 0.0 0.0036 17.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF3089 PF11288.8 CRK27727.1 - 0.007 15.9 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3089) TPP_enzyme_N PF02776.18 CRK27727.1 - 0.018 14.7 0.3 0.18 11.4 0.0 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain ResIII PF04851.15 CRK27727.1 - 0.1 12.6 0.0 0.27 11.2 0.0 1.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit PhoH PF02562.16 CRK27727.1 - 0.22 11.0 0.0 0.35 10.3 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein DNA_binding_1 PF01035.20 CRK27728.1 - 1.7e-28 98.6 0.0 3.4e-28 97.6 0.0 1.5 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain GFA PF04828.14 CRK27728.1 - 0.00013 22.2 0.1 0.13 12.6 0.1 2.6 2 0 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme DUF812 PF05667.11 CRK27730.1 - 0.076 11.9 11.5 0.093 11.6 11.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) LCIB_C_CA PF18599.1 CRK27730.1 - 0.45 9.8 2.3 0.54 9.5 2.3 1.2 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases IHABP4_N PF16174.5 CRK27730.1 - 2.1 8.9 11.5 2.9 8.5 11.5 1.1 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal MFS_1 PF07690.16 CRK27732.1 - 1.2e-38 133.0 40.0 1.2e-38 133.0 40.0 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK27732.1 - 5.5e-12 45.3 4.6 5.5e-12 45.3 4.6 2.6 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 CRK27732.1 - 0.0011 17.5 3.9 0.0021 16.6 3.9 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PTR2 PF00854.21 CRK27732.1 - 0.025 13.4 1.7 0.058 12.2 1.7 1.5 1 0 0 1 1 1 0 POT family RXT2_N PF08595.11 CRK27733.1 - 0.43 10.6 5.0 11 6.0 0.1 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal MAM33 PF02330.16 CRK27733.1 - 0.71 9.8 5.8 1.5 8.7 0.8 2.1 2 0 0 2 2 2 0 Mitochondrial glycoprotein CENP-B_dimeris PF09026.10 CRK27733.1 - 0.75 10.2 23.9 0.74 10.2 4.4 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Myc_N PF01056.18 CRK27733.1 - 0.93 9.3 7.0 1 9.2 1.6 2.2 2 0 0 2 2 2 0 Myc amino-terminal region Pox_Ag35 PF03286.14 CRK27733.1 - 2.8 7.7 7.6 2.1 8.1 0.5 2.4 2 0 0 2 2 2 0 Pox virus Ag35 surface protein eIF-3c_N PF05470.12 CRK27733.1 - 4.9 5.4 3.9 6.9 4.8 3.9 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus NOA36 PF06524.12 CRK27733.1 - 5.1 6.3 16.6 3.6 6.8 1.2 2.2 2 0 0 2 2 2 0 NOA36 protein DUF2457 PF10446.9 CRK27733.1 - 5.9 5.9 17.9 3.1 6.8 6.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Cytomega_UL20A PF05984.12 CRK27734.1 - 0.11 12.8 0.1 0.38 11.1 0.1 1.9 1 0 0 1 1 1 0 Cytomegalovirus UL20A protein CENP-Q PF13094.6 CRK27735.1 - 7.8e-41 140.1 0.2 7.8e-41 140.1 0.2 2.4 2 1 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit Cnl2_NKP2 PF09447.10 CRK27737.1 - 1.8e-26 92.1 2.7 2.1e-26 91.9 0.9 2.0 1 1 1 2 2 2 1 Cnl2/NKP2 family protein OmpH PF03938.14 CRK27737.1 - 0.00057 20.2 1.3 0.17 12.2 0.5 2.1 2 0 0 2 2 2 2 Outer membrane protein (OmpH-like) DUF4407 PF14362.6 CRK27737.1 - 0.013 14.9 2.1 0.016 14.5 2.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Prefoldin_2 PF01920.20 CRK27737.1 - 0.014 15.3 3.6 0.018 15.0 0.2 2.3 2 1 0 2 2 2 0 Prefoldin subunit DUF5082 PF16888.5 CRK27737.1 - 0.02 15.2 2.7 0.042 14.1 0.1 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF5082) CENP-F_leu_zip PF10473.9 CRK27737.1 - 0.022 14.8 2.6 0.045 13.8 1.5 1.9 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 T6PP_N PF18572.1 CRK27737.1 - 0.028 14.2 0.5 0.044 13.6 0.5 1.3 1 0 0 1 1 1 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain DUF3209 PF11483.8 CRK27737.1 - 0.058 13.9 2.0 0.099 13.1 1.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3209) DUF1192 PF06698.11 CRK27737.1 - 0.083 13.0 0.9 0.083 13.0 0.9 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) Nnf1 PF03980.14 CRK27737.1 - 0.13 12.6 4.5 0.17 12.3 2.6 2.0 1 1 1 2 2 2 0 Nnf1 Seryl_tRNA_N PF02403.22 CRK27737.1 - 0.13 12.5 4.1 3 8.1 0.2 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain APG6_N PF17675.1 CRK27737.1 - 0.14 12.7 6.3 0.5 10.9 6.3 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region SlyX PF04102.12 CRK27737.1 - 0.19 12.4 3.7 0.21 12.2 0.1 2.4 2 1 0 2 2 2 0 SlyX DASH_Spc19 PF08287.11 CRK27737.1 - 0.21 11.5 0.1 0.21 11.5 0.1 2.1 2 0 0 2 2 2 0 Spc19 PRKG1_interact PF15898.5 CRK27737.1 - 0.61 11.0 7.2 7.7 7.5 7.2 2.1 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain DivIC PF04977.15 CRK27737.1 - 1.5 8.6 5.3 0.63 9.8 0.1 2.3 2 1 0 2 2 2 0 Septum formation initiator MRG PF05712.13 CRK27738.1 - 1.6e-60 203.8 0.0 4.1e-60 202.5 0.0 1.7 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 CRK27738.1 - 2.4e-08 33.7 1.6 2.4e-08 33.7 1.6 2.0 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Ribosomal_L30 PF00327.20 CRK27740.1 - 9.7e-17 60.6 0.1 1.2e-16 60.3 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Citrate_synt PF00285.21 CRK27741.1 - 2e-11 43.6 0.1 9.1e-07 28.3 0.1 3.2 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain DUF572 PF04502.13 CRK27742.1 - 3.9e-10 39.9 0.0 4.8e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) Pantoate_transf PF02548.15 CRK27742.1 - 8.1e-09 35.2 0.0 1.1e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase 2OG-FeII_Oxy_3 PF13640.6 CRK27743.1 - 7.5e-08 33.2 0.0 1.4e-07 32.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fumble PF03630.14 CRK27746.1 - 1.7e-146 487.7 0.0 2e-146 487.4 0.0 1.1 1 0 0 1 1 1 1 Fumble RGS PF00615.19 CRK27747.1 - 2.1e-06 28.0 0.1 0.0085 16.4 0.0 2.6 2 1 0 2 2 2 2 Regulator of G protein signaling domain DUF1348 PF07080.11 CRK27748.1 - 6e-64 213.8 8.6 7.1e-64 213.6 8.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.7 CRK27748.1 - 1.1e-07 32.4 0.6 1.4e-07 32.0 0.6 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 CRK27748.1 - 9.1e-06 26.0 0.1 1.5e-05 25.4 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) Redoxin PF08534.10 CRK27749.1 - 3.1e-36 124.3 0.0 3.4e-36 124.2 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 CRK27749.1 - 7.3e-07 29.1 0.0 9.1e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Ribosomal_L24e PF01246.20 CRK27750.1 - 1.4e-28 98.9 0.2 3.4e-28 97.7 0.2 1.7 1 0 0 1 1 1 1 Ribosomal protein L24e SSB PF00436.25 CRK27750.1 - 0.24 11.5 3.1 1.5 8.9 2.4 2.0 2 0 0 2 2 2 0 Single-strand binding protein family A_deamin PF02137.18 CRK27751.1 - 2.2e-14 53.7 0.0 2.7e-14 53.4 0.0 1.0 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain CBP4 PF07960.11 CRK27752.1 - 3.1e-28 98.2 1.4 3.8e-28 97.9 1.4 1.0 1 0 0 1 1 1 1 CBP4 Trp_oprn_chp PF09534.10 CRK27752.1 - 0.089 12.6 0.0 0.15 11.9 0.0 1.3 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF2852 PF11014.8 CRK27752.1 - 0.47 10.6 4.1 0.61 10.3 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) Sel1 PF08238.12 CRK27753.1 - 2.6e-41 139.1 26.7 5.4e-08 33.3 0.0 8.1 8 0 0 8 8 8 7 Sel1 repeat TPR_17 PF13431.6 CRK27753.1 - 0.021 15.2 0.9 0.69 10.4 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.6 CRK27753.1 - 0.12 12.7 0.9 1.3 9.4 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 CRK27753.1 - 3 8.9 12.8 0.97 10.4 0.1 5.2 4 1 1 5 5 5 0 Tetratricopeptide repeat MPC PF03650.13 CRK27754.1 - 2.8e-46 156.2 0.3 3.9e-46 155.7 0.3 1.2 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers MtN3_slv PF03083.16 CRK27754.1 - 0.15 12.1 0.5 0.26 11.3 0.5 1.5 1 1 0 1 1 1 0 Sugar efflux transporter for intercellular exchange L51_S25_CI-B8 PF05047.16 CRK27755.1 - 1.2e-13 50.8 0.0 1.5e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain CaM_binding PF07839.11 CRK27755.1 - 0.039 14.7 0.0 0.045 14.5 0.0 1.1 1 0 0 1 1 1 0 Plant calmodulin-binding domain Ribosomal_L14e PF01929.17 CRK27758.1 - 3.2e-29 101.2 3.8 3.2e-29 101.2 3.8 1.7 2 0 0 2 2 2 1 Ribosomal protein L14 Mt_ATP-synt_D PF05873.12 CRK27758.1 - 1.1e-05 25.4 1.5 2e-05 24.5 1.4 1.5 1 1 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) KOW PF00467.29 CRK27758.1 - 0.0027 17.6 0.6 0.0047 16.8 0.0 1.7 2 0 0 2 2 2 1 KOW motif MbeB_N PF04837.12 CRK27758.1 - 0.02 15.2 0.8 0.038 14.3 0.8 1.4 1 0 0 1 1 1 0 MbeB-like, N-term conserved region HHH PF00633.23 CRK27758.1 - 0.043 13.7 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif Amidase PF01425.21 CRK27781.1 - 4.9e-75 253.2 0.1 6.6e-75 252.8 0.1 1.1 1 0 0 1 1 1 1 Amidase ADH_N PF08240.12 CRK27782.1 - 1.1e-21 76.7 0.1 2.3e-21 75.7 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CRK27782.1 - 7.8e-14 51.8 0.0 2e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 CRK27782.1 - 0.022 14.1 0.1 0.036 13.4 0.1 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain XdhC_C PF13478.6 CRK27782.1 - 0.048 14.2 0.0 0.12 12.9 0.0 1.7 1 0 0 1 1 1 0 XdhC Rossmann domain AlaDh_PNT_C PF01262.21 CRK27782.1 - 0.092 12.0 0.1 0.15 11.3 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain adh_short_C2 PF13561.6 CRK27783.1 - 1e-55 188.8 1.5 1.9e-55 188.0 1.5 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRK27783.1 - 1.1e-42 145.7 0.4 2e-42 144.9 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Cofilin_ADF PF00241.20 CRK27783.1 - 1.4e-29 102.4 0.0 6.6e-15 55.0 0.0 2.4 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein KR PF08659.10 CRK27783.1 - 1e-07 32.1 1.5 1.2e-07 31.8 0.3 1.8 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 CRK27783.1 - 0.037 13.2 0.0 0.077 12.1 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ThiF PF00899.21 CRK27783.1 - 0.042 13.2 1.3 0.26 10.6 0.5 2.4 2 1 1 3 3 3 0 ThiF family Methyltransf_25 PF13649.6 CRK27783.1 - 0.079 13.7 0.0 0.82 10.4 0.0 2.6 2 0 0 2 2 2 0 Methyltransferase domain Mito_carr PF00153.27 CRK27785.1 - 9.4e-68 224.2 1.8 2.9e-22 78.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein GRDP-like PF07173.12 CRK27786.1 - 2.8e-05 24.8 1.1 0.032 14.9 0.0 3.3 3 0 0 3 3 3 2 Glycine-rich domain-containing protein-like His_Phos_2 PF00328.22 CRK27786.1 - 4.5e-05 23.0 0.2 0.0032 16.9 0.0 3.0 2 1 1 3 3 3 2 Histidine phosphatase superfamily (branch 2) DUF4366 PF14283.6 CRK27786.1 - 0.16 12.0 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) WD40 PF00400.32 CRK27787.1 - 5.4e-45 150.5 14.9 3.3e-06 27.7 1.1 8.8 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.7 CRK27787.1 - 4.3e-13 48.9 0.9 9.1e-13 47.9 0.9 1.6 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 CRK27787.1 - 1.1e-10 41.7 0.8 0.21 11.9 0.0 5.6 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 CRK27787.1 - 7.7e-10 38.4 0.4 2.1e-09 37.0 0.4 1.8 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 CRK27787.1 - 3.2e-09 36.0 8.4 0.014 14.1 0.1 5.0 3 2 1 5 5 5 4 Nucleoporin Nup120/160 F-box_4 PF15966.5 CRK27787.1 - 3.2e-05 23.8 0.1 0.00012 22.0 0.1 2.0 1 0 0 1 1 1 1 F-box BBS2_Mid PF14783.6 CRK27787.1 - 0.00023 21.2 0.0 2.1 8.4 0.0 3.4 3 0 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region WD40_like PF17005.5 CRK27787.1 - 0.00044 19.7 0.3 0.008 15.5 0.3 2.3 2 1 0 2 2 2 1 WD40-like domain Nucleoporin_N PF08801.11 CRK27787.1 - 0.068 11.9 0.2 0.71 8.6 0.0 2.2 1 1 1 2 2 2 0 Nup133 N terminal like Ge1_WD40 PF16529.5 CRK27787.1 - 0.72 8.7 8.4 22 3.8 0.0 4.5 3 2 3 6 6 6 0 WD40 region of Ge1, enhancer of mRNA-decapping protein HAUS-augmin3 PF14932.6 CRK27788.1 - 0.00014 21.6 13.7 0.0003 20.5 13.6 1.6 1 1 0 1 1 1 1 HAUS augmin-like complex subunit 3 RHH_1 PF01402.21 CRK27788.1 - 0.59 10.2 3.5 9.5 6.3 0.1 4.0 3 0 0 3 3 3 0 Ribbon-helix-helix protein, copG family LrgB PF04172.16 CRK27789.1 - 1.9e-25 89.7 9.0 1.9e-25 89.7 9.0 2.5 2 1 0 2 2 2 1 LrgB-like family Ribosomal_L14 PF00238.19 CRK27790.1 - 2.6e-42 143.8 2.9 5.2e-42 142.8 2.9 1.5 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Rotamase PF00639.21 CRK27790.1 - 5.4e-22 78.6 0.0 1e-21 77.7 0.0 1.5 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 CRK27790.1 - 1.1e-16 61.4 0.0 2.1e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 PPIC-type PPIASE domain RNA_POL_M_15KD PF02150.16 CRK27790.1 - 1.2e-11 44.3 2.7 2.5e-11 43.3 2.7 1.6 1 0 0 1 1 1 1 RNA polymerases M/15 Kd subunit WW PF00397.26 CRK27790.1 - 1.3e-07 31.5 2.7 3e-07 30.4 2.7 1.7 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.6 CRK27790.1 - 0.00023 22.0 0.0 0.00039 21.3 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain Nudix_N_2 PF14803.6 CRK27790.1 - 0.019 14.9 1.6 0.044 13.7 1.6 1.6 1 0 0 1 1 1 0 Nudix N-terminal SET PF00856.28 CRK27791.1 - 5.9e-07 30.0 0.2 3.6e-06 27.5 0.2 2.4 1 1 0 1 1 1 1 SET domain FAM76 PF16046.5 CRK27791.1 - 1.7 7.9 5.6 0.2 11.0 0.8 1.8 2 0 0 2 2 2 0 FAM76 protein APG17 PF04108.12 CRK27792.1 - 3.7e-137 457.7 0.8 4.4e-137 457.4 0.8 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 T2SSF PF00482.23 CRK27792.1 - 0.0001 22.2 1.1 0.00043 20.2 0.4 2.4 2 0 0 2 2 2 1 Type II secretion system (T2SS), protein F HAP1_N PF04849.13 CRK27792.1 - 0.0092 15.2 4.7 0.62 9.2 0.3 2.2 2 0 0 2 2 2 2 HAP1 N-terminal conserved region Glyco_hydro_67N PF03648.14 CRK27792.1 - 0.042 14.1 0.1 0.1 12.9 0.1 1.7 1 0 0 1 1 1 0 Glycosyl hydrolase family 67 N-terminus EzrA PF06160.12 CRK27792.1 - 0.11 10.6 1.0 0.45 8.6 0.3 2.1 2 1 0 2 2 2 0 Septation ring formation regulator, EzrA SF-assemblin PF06705.11 CRK27792.1 - 0.12 11.7 1.5 1.1 8.6 0.1 2.5 3 0 0 3 3 3 0 SF-assemblin/beta giardin CCDC-167 PF15188.6 CRK27792.1 - 0.87 10.0 3.2 2.3 8.6 0.0 3.1 3 1 0 3 3 3 0 Coiled-coil domain-containing protein 167 Cript PF10235.9 CRK27793.1 - 2.4e-19 69.7 7.5 2.4e-19 69.7 7.5 1.4 2 0 0 2 2 2 1 Microtubule-associated protein CRIPT zinc-ribbons_6 PF07191.12 CRK27793.1 - 0.047 13.7 6.6 0.075 13.0 4.1 2.0 2 0 0 2 2 2 0 zinc-ribbons DZR PF12773.7 CRK27793.1 - 0.17 12.0 11.7 0.44 10.6 3.6 2.7 2 1 1 3 3 3 0 Double zinc ribbon RsgA_GTPase PF03193.16 CRK27793.1 - 0.17 11.8 0.3 0.19 11.6 0.3 1.2 1 0 0 1 1 1 0 RsgA GTPase DUF2039 PF10217.9 CRK27793.1 - 0.54 10.6 12.9 0.059 13.7 6.9 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) zinc_ribbon_15 PF17032.5 CRK27793.1 - 7.4 7.4 10.6 4.8 8.0 6.0 2.6 2 1 0 2 2 2 0 zinc-ribbon family Abhydrolase_1 PF00561.20 CRK27794.1 - 3.8e-20 72.6 0.2 1.3e-15 57.8 0.1 2.0 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CRK27794.1 - 8.2e-15 56.0 7.5 1.2e-14 55.4 7.5 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CRK27794.1 - 3.5e-12 46.1 0.0 2.8e-11 43.2 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Glyco_hydro_61 PF03443.14 CRK27795.1 - 2.6e-40 138.6 0.0 2.8e-39 135.2 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 Fungal_trans PF04082.18 CRK27796.1 - 2.6e-12 46.3 0.0 3.5e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Con-6 PF10346.9 CRK27797.1 - 5.2e-17 61.6 1.9 1.3e-16 60.3 1.4 1.8 2 0 0 2 2 2 1 Conidiation protein 6 Transferase PF02458.15 CRK27798.1 - 2.3e-12 46.3 0.0 7.3e-08 31.5 0.0 3.3 3 1 0 3 3 3 3 Transferase family Acetyltransf_1 PF00583.25 CRK27799.1 - 1.6e-16 60.6 0.0 2.6e-16 59.9 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 CRK27799.1 - 6.2e-09 35.7 0.1 1.7e-08 34.3 0.0 1.7 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_7 PF13508.7 CRK27799.1 - 1.1e-07 32.2 0.0 1.6e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 CRK27799.1 - 4.8e-07 30.0 0.0 2.8e-05 24.3 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 CRK27799.1 - 4.2e-06 27.5 0.0 5.9e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CRK27799.1 - 7.9e-06 25.8 0.0 1.2e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CRK27799.1 - 0.024 14.8 0.0 0.039 14.1 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 CRK27799.1 - 0.061 13.4 0.1 0.59 10.2 0.1 2.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain PanZ PF12568.8 CRK27799.1 - 0.071 12.8 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Plant_NMP1 PF06694.11 CRK27799.1 - 0.18 10.9 0.0 0.29 10.2 0.0 1.3 1 0 0 1 1 1 0 Plant nuclear matrix protein 1 (NMP1) Complex1_LYR PF05347.15 CRK27800.1 - 6.9e-08 32.4 0.7 2.4e-07 30.7 0.7 2.0 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 CRK27800.1 - 0.0052 17.5 3.1 0.0052 17.5 3.1 2.4 2 1 0 2 2 2 1 Complex1_LYR-like Ank_2 PF12796.7 CRK27801.1 - 4.1e-13 49.7 0.2 7.7e-05 23.2 0.1 3.6 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CRK27801.1 - 5.4e-13 49.2 4.7 1.5e-07 31.8 0.2 4.3 3 2 3 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CRK27801.1 - 2.7e-09 36.5 0.8 0.01 16.3 0.0 4.9 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 CRK27801.1 - 1.9e-08 34.4 4.4 0.076 13.5 0.1 4.8 5 0 0 5 5 5 2 Ankyrin repeat KilA-N PF04383.13 CRK27801.1 - 1.4e-05 24.9 0.9 0.0001 22.1 0.3 2.5 2 1 0 2 2 2 1 KilA-N domain Ank_5 PF13857.6 CRK27801.1 - 6.4e-05 23.1 0.4 0.92 9.9 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Med2 PF11214.8 CRK27801.1 - 0.054 13.7 4.2 0.12 12.6 4.2 1.6 1 0 0 1 1 1 0 Mediator complex subunit 2 HrpB1_HrpK PF09613.10 CRK27801.1 - 0.056 13.1 0.7 0.15 11.7 0.7 1.6 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) DUF4407 PF14362.6 CRK27801.1 - 0.67 9.3 6.9 1.7 7.9 6.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Muted PF14942.6 CRK27801.1 - 0.84 10.0 7.3 1.9 8.8 7.3 1.6 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein NAD_binding_7 PF13241.6 CRK27802.1 - 3e-30 104.7 0.0 6.9e-30 103.6 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 CRK27802.1 - 5.8e-27 93.1 0.1 4e-26 90.4 0.0 2.4 2 0 0 2 2 2 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 CRK27802.1 - 4.9e-16 57.9 1.4 2e-15 55.9 0.1 2.5 2 0 0 2 2 2 1 Sirohaem biosynthesis protein central FYVE PF01363.21 CRK27802.1 - 1.5e-08 34.6 8.9 6.4e-07 29.4 7.1 3.1 3 0 0 3 3 3 1 FYVE zinc finger zf-AN1 PF01428.16 CRK27802.1 - 0.00069 19.7 2.7 0.00069 19.7 2.7 2.2 2 0 0 2 2 2 1 AN1-like Zinc finger Pyr_redox_3 PF13738.6 CRK27802.1 - 0.0085 15.4 0.0 0.018 14.3 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase zf-Di19 PF05605.12 CRK27802.1 - 0.047 14.0 0.1 0.047 14.0 0.1 2.1 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_12 PF18658.1 CRK27802.1 - 0.056 13.0 0.0 0.21 11.2 0.0 1.9 1 0 0 1 1 1 0 Zinc-finger C2H2-type zf-ribbon_3 PF13248.6 CRK27802.1 - 0.29 10.6 4.7 5.6 6.5 0.7 3.4 3 0 0 3 3 3 0 zinc-ribbon domain IBR PF01485.21 CRK27802.1 - 1.1 9.5 5.2 0.55 10.5 0.9 2.6 3 0 0 3 3 3 0 IBR domain, a half RING-finger domain zf-C2H2_4 PF13894.6 CRK27802.1 - 3.3 8.8 0.0 3.3 8.8 0.0 4.6 5 0 0 5 5 4 0 C2H2-type zinc finger DUF2953 PF11167.8 CRK27804.1 - 0.14 12.3 0.7 3.9 7.6 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2953) WD40 PF00400.32 CRK27805.1 - 3.2e-10 40.4 4.2 8.8e-06 26.4 0.1 3.0 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK27805.1 - 0.00023 21.4 0.1 0.69 10.2 0.0 2.2 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain bZIP_2 PF07716.15 CRK27807.1 - 3e-05 24.0 8.6 5.1e-05 23.3 8.6 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 CRK27807.1 - 3.5e-05 23.8 5.0 6e-05 23.1 5.0 1.3 1 0 0 1 1 1 1 bZIP transcription factor Fes1 PF08609.10 CRK27807.1 - 0.067 14.1 0.0 0.2 12.6 0.0 1.8 1 0 0 1 1 1 0 Nucleotide exchange factor Fes1 TTKRSYEDQ PF10212.9 CRK27807.1 - 0.14 11.2 0.0 0.2 10.6 0.0 1.1 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein bZIP_Maf PF03131.17 CRK27807.1 - 1.1 9.9 6.0 0.11 13.0 1.2 1.8 2 0 0 2 2 2 0 bZIP Maf transcription factor CENP-L PF13092.6 CRK27808.1 - 5.7e-52 176.2 0.0 8.4e-52 175.7 0.0 1.3 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 Cupin_1 PF00190.22 CRK27809.1 - 4.9e-06 26.2 0.5 7.6e-06 25.6 0.5 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 CRK27809.1 - 2e-05 24.2 0.1 3.4e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 Cupin domain DAO PF01266.24 CRK27810.1 - 2.9e-44 152.1 1.2 4.3e-44 151.5 1.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CRK27810.1 - 4e-05 23.7 0.0 0.00011 22.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CRK27810.1 - 0.00029 20.2 0.0 0.21 10.8 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CRK27810.1 - 0.0075 16.8 0.0 0.037 14.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CRK27810.1 - 0.009 16.0 1.2 4.7 7.2 0.4 2.7 2 1 0 2 2 2 2 FAD-NAD(P)-binding GIDA PF01134.22 CRK27810.1 - 0.017 14.3 0.0 0.073 12.1 0.0 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A Sacchrp_dh_NADP PF03435.18 CRK27810.1 - 0.089 13.1 0.0 0.37 11.0 0.0 2.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Thi4 PF01946.17 CRK27810.1 - 0.18 11.0 0.0 0.39 9.9 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Sugar_tr PF00083.24 CRK27811.1 - 9.2e-86 288.5 23.5 1.1e-85 288.3 23.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK27811.1 - 2.9e-47 161.3 47.1 1.6e-37 129.2 25.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CRK27811.1 - 0.0026 16.3 3.2 0.0026 16.3 3.2 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Scm3 PF10384.9 CRK27811.1 - 0.038 13.7 0.0 0.071 12.9 0.0 1.3 1 0 0 1 1 1 0 Centromere protein Scm3 Peptidase_M43 PF05572.13 CRK27812.1 - 5.5e-11 42.6 0.0 1.2e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 CRK27812.1 - 2.5e-08 34.5 0.0 4.9e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 CRK27812.1 - 3.7e-06 27.2 0.0 7.9e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12 DUF4953 PF16313.5 CRK27812.1 - 0.0064 15.8 0.1 0.027 13.7 0.0 1.9 2 0 0 2 2 2 1 Met-zincin Reprolysin_4 PF13583.6 CRK27812.1 - 0.0067 16.1 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 CRK27812.1 - 0.012 15.5 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 Matrixin Reprolysin PF01421.19 CRK27812.1 - 0.018 14.9 0.0 0.029 14.3 0.0 1.3 1 0 0 1 1 1 0 Reprolysin (M12B) family zinc metalloprotease Peptidase_M66 PF10462.9 CRK27812.1 - 0.032 13.2 0.0 0.05 12.5 0.0 1.2 1 0 0 1 1 1 0 Peptidase M66 Syja_N PF02383.18 CRK27813.1 - 1.2e-52 179.2 0.0 2.1e-47 162.0 0.0 2.6 3 0 0 3 3 3 2 SacI homology domain SAM_PNT PF02198.16 CRK27813.1 - 0.12 12.3 0.1 8.1 6.5 0.1 2.5 2 0 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain Suf PF05843.14 CRK27815.1 - 8.1e-13 49.0 7.6 0.014 15.4 0.0 6.9 3 2 2 6 6 6 4 Suppressor of forked protein (Suf) TPR_14 PF13428.6 CRK27815.1 - 3.2e-11 43.1 19.6 3.4 8.7 0.6 11.4 11 2 1 12 12 12 3 Tetratricopeptide repeat TPR_15 PF13429.6 CRK27815.1 - 2e-06 27.2 5.4 0.00016 21.0 0.4 4.2 2 2 2 4 4 4 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 CRK27815.1 - 0.00029 20.8 10.3 0.32 11.0 0.0 6.5 7 1 0 7 7 7 1 Mad3/BUB1 homology region 1 TPR_8 PF13181.6 CRK27815.1 - 0.00047 20.2 3.1 3.8 8.0 0.0 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat NRDE-2 PF08424.10 CRK27815.1 - 0.0025 17.0 10.1 0.065 12.3 1.2 5.5 3 2 2 5 5 5 1 NRDE-2, necessary for RNA interference TPR_12 PF13424.6 CRK27815.1 - 0.0057 16.9 2.9 1e+02 3.3 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat RPN7 PF10602.9 CRK27815.1 - 0.035 13.8 0.4 0.8 9.4 0.5 2.8 2 1 0 2 2 2 0 26S proteasome subunit RPN7 TPR_10 PF13374.6 CRK27815.1 - 1.3 9.0 7.3 55 3.8 0.0 5.1 4 0 0 4 4 4 0 Tetratricopeptide repeat ATP-synt_D PF01813.17 CRK27816.1 - 1.4e-70 237.1 0.9 1.8e-70 236.8 0.9 1.1 1 0 0 1 1 1 1 ATP synthase subunit D SYCE1 PF15233.6 CRK27816.1 - 0.088 12.9 0.9 1.4 9.0 0.1 2.3 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 RICH PF05062.12 CRK27816.1 - 0.1 12.9 2.4 0.22 11.9 0.4 2.2 2 0 0 2 2 2 0 RICH domain PHM7_cyt PF14703.6 CRK27816.1 - 0.17 12.1 3.2 0.37 11.0 0.8 2.2 2 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter CobA_CobO_BtuR PF02572.15 CRK27816.1 - 0.34 11.2 3.1 1 9.6 0.1 2.3 2 1 1 3 3 3 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP DUF5446 PF17522.2 CRK27816.1 - 0.56 10.4 2.3 0.86 9.8 0.7 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5446) Anp1 PF03452.14 CRK27817.1 - 2.2e-112 374.8 0.0 4.1e-112 373.9 0.0 1.5 1 0 0 1 1 1 1 Anp1 Sec7 PF01369.20 CRK27817.1 - 2.3e-65 219.7 0.0 3.6e-65 219.1 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 CRK27817.1 - 2.1e-17 63.5 0.0 2.9e-16 59.8 0.0 2.9 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal TP53IP5 PF15331.6 CRK27817.1 - 0.35 11.0 2.0 0.76 9.9 2.0 1.5 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 RNase_PH PF01138.21 CRK27818.1 - 1.8e-27 96.5 0.0 2.1e-26 93.0 0.0 2.3 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNA_pol_Rpb8 PF03870.15 CRK27820.1 - 1.6e-45 154.7 0.0 1.8e-45 154.6 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 CRK27820.1 - 0.00016 21.7 0.2 0.21 11.6 0.0 2.1 2 0 0 2 2 2 2 DNA-directed RNA polymerase, subunit G GDA1_CD39 PF01150.17 CRK27821.1 - 3.5e-105 352.1 0.0 5.1e-105 351.6 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DUF4743 PF15916.5 CRK27821.1 - 2.3e-10 40.5 0.0 3.9e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 CRK27821.1 - 5.2e-09 36.2 0.1 1.5e-08 34.7 0.0 1.8 2 0 0 2 2 2 1 NUDIX domain DUF775 PF05603.12 CRK27822.1 - 2.5e-59 200.2 0.0 2.9e-59 200.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) RNase_P_Rpp14 PF01900.19 CRK27823.1 - 7.4e-35 119.3 0.0 9.8e-35 118.9 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family RIF5_SNase_2 PF18189.1 CRK27823.1 - 0.066 13.0 0.1 0.098 12.5 0.1 1.2 1 0 0 1 1 1 0 TbRIF5 SNase domain 2 cNMP_binding PF00027.29 CRK27824.1 - 4.4e-29 100.4 1.1 5.8e-16 58.3 0.1 6.0 6 0 0 6 6 6 3 Cyclic nucleotide-binding domain Patatin PF01734.22 CRK27824.1 - 1.4e-16 61.3 3.2 9e-16 58.7 3.2 2.4 1 1 0 1 1 1 1 Patatin-like phospholipase MOSC PF03473.17 CRK27826.1 - 5.4e-21 75.0 0.0 9.5e-21 74.2 0.0 1.4 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 CRK27826.1 - 2.5e-13 49.9 0.0 4.9e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain PHP PF02811.19 CRK27826.1 - 2.3e-10 41.0 0.0 4.3e-10 40.1 0.0 1.5 1 1 0 1 1 1 1 PHP domain His_Phos_2 PF00328.22 CRK27828.1 - 3.4e-33 115.5 0.0 4.6e-33 115.1 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Utp21 PF04192.12 CRK27830.1 - 5.9e-82 274.6 0.0 7.6e-82 274.3 0.0 1.1 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 CRK27830.1 - 3.5e-07 30.8 2.2 2e-06 28.4 0.8 2.8 3 0 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK27830.1 - 0.00045 20.5 0.0 0.016 15.5 0.0 2.5 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 CRK27830.1 - 0.00089 17.9 0.0 0.0014 17.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome D1 heme domain fn3_3 PF14686.6 CRK27831.1 - 3.6e-27 94.0 0.7 7.5e-27 92.9 0.7 1.6 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CBM-like PF14683.6 CRK27831.1 - 4e-23 82.1 0.0 7.1e-23 81.3 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III RhgB_N PF09284.10 CRK27831.1 - 0.001 18.7 2.1 0.02 14.5 0.2 2.8 3 0 0 3 3 3 1 Rhamnogalacturonan lyase B, N-terminal CarboxypepD_reg PF13620.6 CRK27831.1 - 0.096 13.0 0.1 0.25 11.7 0.1 1.7 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain Nudix_N PF12535.8 CRK27831.1 - 0.16 11.6 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 Hydrolase of X-linked nucleoside diphosphate N terminal Glyco_hydro_76 PF03663.14 CRK27832.1 - 4e-44 151.6 16.1 4.6e-43 148.1 16.1 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 CRK27832.1 - 8.7e-07 28.3 0.4 0.0023 17.1 0.0 2.9 1 1 0 2 2 2 2 Glycosyl Hydrolase Family 88 TGT PF01702.18 CRK27833.1 - 2.6e-141 470.8 0.0 3.1e-141 470.6 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Ribosomal_S17e PF00833.18 CRK27834.1 - 3.2e-59 198.2 0.3 3.7e-59 198.0 0.3 1.0 1 0 0 1 1 1 1 Ribosomal S17 Arginosuc_synth PF00764.19 CRK27835.1 - 1.8e-149 498.3 0.0 2.1e-149 498.1 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 CRK27835.1 - 0.011 15.3 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 CRK27835.1 - 0.18 10.6 0.0 0.26 10.0 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase SH3_1 PF00018.28 CRK27836.1 - 1.2e-09 37.7 0.1 2.7e-09 36.5 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CRK27836.1 - 4.4e-09 36.1 0.4 8.7e-09 35.1 0.4 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CRK27836.1 - 3.1e-05 23.6 0.0 6e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain GCP_N_terminal PF17681.1 CRK27837.1 - 4e-25 89.1 0.0 6.2e-25 88.5 0.0 1.2 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 CRK27837.1 - 3.5e-23 82.6 0.0 1.4e-22 80.5 0.0 1.9 1 1 0 1 1 1 1 Gamma tubulin complex component C-terminal PTP_N PF12453.8 CRK27838.1 - 0.57 10.0 1.7 1.3 8.8 1.7 1.6 1 0 0 1 1 1 0 Protein tyrosine phosphatase N terminal Methyltransf_33 PF10017.9 CRK27839.1 - 5.1e-82 275.5 0.0 7.7e-82 274.9 0.0 1.2 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.16 CRK27839.1 - 7.5e-15 55.2 0.0 1.5e-13 51.0 0.0 2.3 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 CRK27839.1 - 4.8e-05 23.9 0.8 4.8e-05 23.9 0.8 2.1 2 0 0 2 2 2 1 DinB superfamily HK_sensor PF16750.5 CRK27839.1 - 0.029 14.6 0.1 0.12 12.7 0.1 1.9 2 0 0 2 2 2 0 Sensor domain of 2-component histidine kinase IF-2B PF01008.17 CRK27840.1 - 1.8e-40 139.0 0.0 2.3e-40 138.6 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family DUF1681 PF07933.14 CRK27841.1 - 1.1e-56 190.7 0.0 2e-56 189.8 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1681) Ku PF02735.16 CRK27842.1 - 7.6e-45 153.1 0.0 1.8e-44 151.9 0.0 1.6 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 CRK27842.1 - 4.2e-33 114.9 0.1 6.3e-33 114.4 0.1 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 CRK27842.1 - 1.6e-26 92.8 3.0 1.6e-26 92.8 3.0 2.1 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm Radical_SAM PF04055.21 CRK27842.1 - 2.2e-07 31.4 0.0 3.9e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 CRK27842.1 - 0.0011 19.3 0.0 0.0023 18.2 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 CRK27842.1 - 0.1 12.7 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 4Fe-4S single cluster domain SAP PF02037.27 CRK27842.1 - 0.16 11.7 0.1 0.35 10.7 0.1 1.6 1 0 0 1 1 1 0 SAP domain Ferrochelatase PF00762.19 CRK27844.1 - 1.2e-94 317.0 0.0 1.7e-94 316.5 0.0 1.2 1 0 0 1 1 1 1 Ferrochelatase HIT PF01230.23 CRK27844.1 - 1.7e-18 67.1 0.0 4.4e-18 65.8 0.0 1.7 1 0 0 1 1 1 1 HIT domain AAA PF00004.29 CRK27844.1 - 3.3e-10 40.5 0.0 7.2e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CRK27844.1 - 5.9e-06 26.6 0.0 1.5e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CRK27844.1 - 6.8e-05 22.9 0.0 0.00013 22.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Rad17 PF03215.15 CRK27844.1 - 6.9e-05 22.8 0.0 0.00018 21.5 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain RuvB_N PF05496.12 CRK27844.1 - 0.00013 21.8 0.0 0.00024 20.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 CRK27844.1 - 0.0021 17.8 0.3 0.0047 16.7 0.3 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CRK27844.1 - 0.0026 17.9 0.0 0.0067 16.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CRK27844.1 - 0.0027 18.1 0.3 0.0079 16.6 0.0 1.9 2 0 0 2 2 1 1 AAA ATPase domain NTPase_1 PF03266.15 CRK27844.1 - 0.012 15.6 0.1 0.14 12.0 0.0 2.4 2 0 0 2 2 2 0 NTPase AAA_14 PF13173.6 CRK27844.1 - 0.013 15.6 0.0 0.026 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain DcpS_C PF11969.8 CRK27844.1 - 0.04 14.4 0.0 0.15 12.6 0.0 1.9 1 1 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding AAA_18 PF13238.6 CRK27844.1 - 0.044 14.3 0.0 0.097 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 CRK27844.1 - 0.062 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_19 PF13245.6 CRK27844.1 - 0.083 13.2 0.1 0.25 11.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 CRK27844.1 - 0.17 11.1 0.0 0.3 10.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain MFS_1 PF07690.16 CRK27846.1 - 2.9e-22 79.1 32.1 1.9e-15 56.7 14.1 3.4 2 1 1 3 3 3 3 Major Facilitator Superfamily DUF5326 PF17260.2 CRK27846.1 - 0.00099 19.2 2.7 0.00099 19.2 2.7 3.6 4 0 0 4 4 4 1 Family of unknown function (DUF5326) Myb_Cef PF11831.8 CRK27847.1 - 1.3e-52 178.8 1.5 1.3e-52 178.8 1.5 3.2 3 0 0 3 3 3 1 pre-mRNA splicing factor component Semialdhyde_dh PF01118.24 CRK27847.1 - 3.2e-28 98.6 0.0 8.1e-28 97.3 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Myb_DNA-binding PF00249.31 CRK27847.1 - 1.1e-22 79.9 5.2 1.5e-10 41.1 0.9 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CRK27847.1 - 8.8e-21 73.9 6.9 1.4e-14 54.0 2.9 2.8 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.8 CRK27847.1 - 0.0021 18.1 0.0 0.031 14.3 0.0 2.8 2 0 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain MFS_1 PF07690.16 CRK27848.1 - 2.9e-42 144.9 43.8 6.9e-42 143.6 43.8 1.6 1 0 0 1 1 1 1 Major Facilitator Superfamily Pkinase PF00069.25 CRK27848.1 - 2e-18 66.7 0.0 3.7e-18 65.8 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Sugar_tr PF00083.24 CRK27848.1 - 4.2e-13 49.0 12.4 1.2e-12 47.4 7.6 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 CRK27848.1 - 1.1e-08 34.0 9.0 1.6e-08 33.5 9.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pkinase_Tyr PF07714.17 CRK27848.1 - 0.00042 19.7 0.0 0.0018 17.6 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase OATP PF03137.20 CRK27848.1 - 3.7 5.7 12.3 0.087 11.1 2.3 2.7 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DEAD PF00270.29 CRK27849.1 - 4.3e-49 166.6 0.0 9e-49 165.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CRK27849.1 - 1.7e-24 86.3 0.0 8.8e-23 80.8 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 CRK27849.1 - 3.9e-22 78.3 6.6 1.4e-21 76.5 6.6 2.1 1 0 0 1 1 1 1 DBP10CT (NUC160) domain ResIII PF04851.15 CRK27849.1 - 2.1e-07 31.1 0.0 4.8e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AP2 PF00847.20 CRK27849.1 - 0.04 14.1 3.4 0.37 11.1 3.4 2.7 1 1 0 1 1 1 0 AP2 domain DnaJ PF00226.31 CRK27850.1 - 4.2e-14 52.4 1.7 6.5e-14 51.8 0.3 2.0 2 0 0 2 2 2 1 DnaJ domain Myb_Cef PF11831.8 CRK27852.1 - 9.9e-53 179.1 1.4 9.9e-53 179.1 1.4 3.3 3 0 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 CRK27852.1 - 3.8e-23 81.4 5.2 8.6e-11 41.9 0.9 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CRK27852.1 - 1.7e-21 76.2 6.8 7.9e-15 54.9 2.8 2.9 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.8 CRK27852.1 - 0.11 12.6 0.0 0.11 12.6 0.0 3.3 5 0 0 5 5 5 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain HRDC PF00570.23 CRK27852.1 - 0.29 11.1 2.7 4.5 7.3 0.0 3.8 4 0 0 4 4 4 0 HRDC domain MFS_1 PF07690.16 CRK27853.1 - 4.8e-42 144.1 45.0 1.2e-41 142.8 45.0 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK27853.1 - 5.4e-12 45.3 17.7 3.2e-11 42.8 12.9 2.3 1 1 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 CRK27853.1 - 1.1e-05 24.1 19.3 1.4e-05 23.7 19.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 CRK27853.1 - 0.27 9.5 12.6 0.06 11.6 2.3 2.6 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DEAD PF00270.29 CRK27854.1 - 1.8e-49 167.9 0.0 3.8e-49 166.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CRK27854.1 - 1.7e-24 86.3 0.0 8.7e-23 80.8 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 CRK27854.1 - 3.7e-22 78.3 6.6 1.4e-21 76.5 6.6 2.1 1 0 0 1 1 1 1 DBP10CT (NUC160) domain ResIII PF04851.15 CRK27854.1 - 1.9e-07 31.3 0.0 4.3e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AP2 PF00847.20 CRK27854.1 - 0.27 11.5 6.7 0.37 11.1 3.4 3.0 2 1 0 2 2 2 0 AP2 domain Pox_RNA_Pol_19 PF05320.12 CRK27854.1 - 2.1 8.3 4.6 5.5 6.9 4.6 1.7 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit CHAD PF05235.14 CRK27854.1 - 5.3 6.9 10.5 0.11 12.5 3.5 1.6 2 0 0 2 2 2 0 CHAD domain DnaJ PF00226.31 CRK27855.1 - 4.2e-14 52.4 1.7 6.5e-14 51.8 0.3 2.0 2 0 0 2 2 2 1 DnaJ domain BCCT PF02028.17 CRK27856.1 - 0.021 13.3 0.2 0.032 12.7 0.2 1.2 1 0 0 1 1 1 0 BCCT, betaine/carnitine/choline family transporter Med25_SD1 PF11235.8 CRK27856.1 - 0.037 14.4 0.5 0.33 11.3 0.1 2.5 2 0 0 2 2 2 0 Mediator complex subunit 25 synapsin 1 BUD22 PF09073.10 CRK27856.1 - 0.07 12.5 18.6 0.13 11.6 18.6 1.4 1 0 0 1 1 1 0 BUD22 CNDH2_C PF16858.5 CRK27856.1 - 0.071 13.0 6.5 0.14 12.0 6.5 1.5 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term RNA_pol_3_Rpc31 PF11705.8 CRK27856.1 - 0.41 10.9 22.1 0.08 13.2 18.4 1.6 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Nop14 PF04147.12 CRK27856.1 - 0.57 8.3 18.9 0.92 7.6 18.9 1.3 1 0 0 1 1 1 0 Nop14-like family Astro_capsid_p PF12226.8 CRK27856.1 - 0.78 8.8 17.6 1.3 8.1 17.6 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein SDA1 PF05285.12 CRK27856.1 - 0.84 9.0 17.9 1.3 8.4 17.9 1.2 1 0 0 1 1 1 0 SDA1 Cwf_Cwc_15 PF04889.12 CRK27856.1 - 3.7 7.2 16.7 8 6.1 16.7 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RRN3 PF05327.11 CRK27856.1 - 5.5 5.4 16.6 22 3.4 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 BCCT PF02028.17 CRK27857.1 - 0.0046 15.5 0.3 0.0065 15.0 0.3 1.1 1 0 0 1 1 1 1 BCCT, betaine/carnitine/choline family transporter Med25_SD1 PF11235.8 CRK27857.1 - 0.0094 16.3 0.3 0.11 12.8 0.0 2.1 2 0 0 2 2 2 1 Mediator complex subunit 25 synapsin 1 HEAT PF02985.22 CRK27857.1 - 0.58 10.6 5.1 0.59 10.5 0.2 2.9 3 0 0 3 3 3 0 HEAT repeat DUF202 PF02656.15 CRK27859.1 - 8.1e-17 61.4 1.6 1.1e-15 57.7 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Yip1 PF04893.17 CRK27859.1 - 0.018 14.8 1.0 0.032 14.0 0.2 1.7 2 0 0 2 2 2 0 Yip1 domain Oxidored_q3 PF00499.20 CRK27859.1 - 0.052 13.3 2.4 0.075 12.7 2.4 1.2 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 COX4_pro_2 PF07835.12 CRK27859.1 - 0.28 11.3 0.0 0.28 11.3 0.0 2.2 2 0 0 2 2 2 0 Bacterial aa3 type cytochrome c oxidase subunit IV Lon_C PF05362.13 CRK27860.1 - 1.4e-87 292.5 6.7 1.4e-66 224.0 0.6 2.7 2 1 1 3 3 3 2 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 CRK27860.1 - 7.8e-25 88.0 0.0 1.5e-24 87.0 0.0 1.5 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 CRK27860.1 - 3.3e-22 79.3 0.0 9.1e-22 77.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.6 CRK27860.1 - 6e-12 45.5 0.7 3e-06 27.1 0.0 3.3 3 0 0 3 3 3 2 Subunit ChlI of Mg-chelatase AAA_5 PF07728.14 CRK27860.1 - 2.3e-07 30.9 0.0 6.7e-07 29.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 CRK27860.1 - 1.3e-05 25.0 0.0 3.3e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.6 CRK27860.1 - 2e-05 25.0 0.0 6.3e-05 23.4 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_3 PF07726.11 CRK27860.1 - 7.2e-05 22.7 0.0 0.00025 20.9 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CRK27860.1 - 9.7e-05 22.2 0.0 0.00055 19.7 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CRK27860.1 - 0.00063 20.0 0.0 0.055 13.7 0.0 2.8 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 CRK27860.1 - 0.00075 19.7 0.0 0.0021 18.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 CRK27860.1 - 0.0056 15.9 1.2 0.014 14.6 0.0 1.9 2 0 0 2 2 2 1 TIP49 P-loop domain NACHT PF05729.12 CRK27860.1 - 0.012 15.5 0.1 0.042 13.8 0.0 1.9 2 0 0 2 2 1 0 NACHT domain AAA_18 PF13238.6 CRK27860.1 - 0.015 15.8 0.0 0.037 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CRK27860.1 - 0.025 15.0 0.0 0.063 13.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 CRK27860.1 - 0.04 13.5 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 CRK27860.1 - 0.041 13.8 0.0 0.13 12.2 0.0 1.8 1 0 0 1 1 1 0 RsgA GTPase NTPase_1 PF03266.15 CRK27860.1 - 0.047 13.6 0.1 0.13 12.1 0.1 1.9 1 1 0 1 1 1 0 NTPase AAA_33 PF13671.6 CRK27860.1 - 0.047 13.8 0.0 0.099 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 CRK27860.1 - 0.063 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Glyco_hydro_3 PF00933.21 CRK27860.1 - 0.065 12.6 0.0 9.6 5.5 0.0 2.4 2 0 0 2 2 2 0 Glycosyl hydrolase family 3 N terminal domain Mg_chelatase PF01078.21 CRK27860.1 - 0.085 12.2 0.2 0.2 11.0 0.2 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 CRK27860.1 - 0.11 12.5 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_24 PF13479.6 CRK27860.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CRK27860.1 - 0.12 12.9 0.0 0.12 12.9 0.0 2.5 1 1 0 2 2 1 0 AAA domain AAA_14 PF13173.6 CRK27860.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 CRK27860.1 - 0.14 11.3 0.0 0.27 10.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Mlh1_C PF16413.5 CRK27863.1 - 7.7e-99 330.4 0.0 1.2e-98 329.8 0.0 1.3 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 CRK27863.1 - 5.3e-33 113.2 0.1 9.8e-33 112.4 0.1 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 CRK27863.1 - 2.1e-11 43.8 0.0 5.2e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CRK27863.1 - 6.3e-06 26.7 0.0 1.5e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Asparaginase_2 PF01112.18 CRK27864.1 - 3.4e-73 246.3 6.5 5.3e-73 245.7 6.5 1.1 1 0 0 1 1 1 1 Asparaginase Mito_carr PF00153.27 CRK27864.1 - 4.1e-14 52.3 0.2 1.8e-08 34.2 0.0 3.1 2 1 0 2 2 2 2 Mitochondrial carrier protein Ank PF00023.30 CRK27865.1 - 1.2e-10 41.4 0.7 3.8e-06 27.1 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 CRK27865.1 - 1.3e-08 35.3 0.0 1.2e-05 25.8 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CRK27865.1 - 1e-07 32.4 0.1 5.5e-06 26.8 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 CRK27865.1 - 1.3e-07 31.4 0.2 3.9e-06 26.8 0.1 3.0 2 1 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 CRK27865.1 - 1.1e-05 25.6 0.1 0.0011 19.2 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Chromo_shadow PF01393.19 CRK27867.1 - 3.2e-19 68.8 0.2 4.2e-19 68.4 0.2 1.2 1 0 0 1 1 1 1 Chromo shadow domain DUF4944 PF16302.5 CRK27867.1 - 0.0094 16.0 0.0 0.012 15.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4944) VIGSSK PF14773.6 CRK27871.1 - 3.7e-26 91.0 2.0 1.3e-25 89.3 2.0 2.0 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.31 CRK27871.1 - 4.5e-14 52.7 0.0 2.7e-13 50.2 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain MARVEL PF01284.23 CRK27872.1 - 8.3e-17 61.6 15.3 1e-16 61.3 15.3 1.1 1 0 0 1 1 1 1 Membrane-associating domain ABC2_membrane_5 PF13346.6 CRK27872.1 - 0.017 14.6 7.0 0.025 14.1 7.0 1.2 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF4149 PF13664.6 CRK27872.1 - 0.074 13.4 3.5 0.59 10.5 0.7 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) Pox_A14 PF05767.12 CRK27872.1 - 0.12 12.6 3.9 0.57 10.4 0.2 2.2 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 Zn_peptidase_2 PF04298.12 CRK27872.1 - 0.99 8.8 5.8 0.14 11.5 2.2 1.4 2 0 0 2 2 2 0 Putative neutral zinc metallopeptidase YpzI PF14140.6 CRK27873.1 - 0.01 15.6 16.5 16 5.3 0.3 5.6 5 0 0 5 5 5 0 YpzI-like protein APG5 PF04106.12 CRK27874.1 - 8.2e-42 143.3 0.0 3.4e-41 141.3 0.0 1.8 1 1 0 1 1 1 1 Autophagy protein Apg5 PKS_DE PF18369.1 CRK27874.1 - 0.15 12.7 1.2 5.3 7.7 0.0 3.2 3 0 0 3 3 3 0 Polyketide synthase dimerisation element domain OB_NTP_bind PF07717.16 CRK27876.1 - 1.9e-22 79.4 0.0 4.3e-22 78.3 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 CRK27876.1 - 6.5e-20 71.4 0.1 1.3e-19 70.5 0.1 1.4 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CRK27876.1 - 1.1e-11 45.1 0.0 2.3e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain But2 PF09792.9 CRK27877.1 - 0.13 12.6 0.0 0.48 10.8 0.0 1.9 1 1 0 1 1 1 0 Ubiquitin 3 binding protein But2 C-terminal domain OB_NTP_bind PF07717.16 CRK27878.1 - 1.2e-21 76.9 0.0 2.6e-21 75.7 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 CRK27878.1 - 8.2e-19 67.9 0.1 8.2e-19 67.9 0.1 4.3 4 0 0 4 4 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CRK27878.1 - 2.7e-14 53.4 0.0 7.6e-14 52.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 CRK27878.1 - 1.5e-13 51.2 2.2 4.8e-05 23.6 0.0 4.1 2 2 2 4 4 4 2 AAA domain DEAD PF00270.29 CRK27878.1 - 1.7e-11 44.2 0.1 0.00028 20.7 0.0 2.6 2 0 0 2 2 2 2 DEAD/DEAH box helicase AAA_30 PF13604.6 CRK27878.1 - 3.1e-09 36.8 0.6 0.0035 17.1 0.1 2.8 2 0 0 2 2 2 2 AAA domain T2SSE PF00437.20 CRK27878.1 - 2.5e-08 33.3 0.2 0.0062 15.6 0.0 2.6 2 0 0 2 2 2 2 Type II/IV secretion system protein SRP54 PF00448.22 CRK27878.1 - 5.7e-07 29.4 1.0 0.04 13.5 0.1 2.8 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain AAA_19 PF13245.6 CRK27878.1 - 7.9e-06 26.3 3.6 0.099 13.0 0.1 3.1 4 0 0 4 4 2 2 AAA domain AAA_16 PF13191.6 CRK27878.1 - 9.2e-05 22.9 0.1 1.3 9.4 0.1 3.5 2 1 0 2 2 2 2 AAA ATPase domain ABC_tran PF00005.27 CRK27878.1 - 9.6e-05 22.9 3.8 0.59 10.6 0.0 3.9 4 0 0 4 4 3 2 ABC transporter PhoH PF02562.16 CRK27878.1 - 0.00022 20.7 0.0 0.86 9.0 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein Roc PF08477.13 CRK27878.1 - 0.00032 20.9 0.2 1.5 9.0 0.0 2.7 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 CRK27878.1 - 0.001 19.1 1.3 7.5 6.6 0.1 4.4 2 2 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 CRK27878.1 - 0.0024 17.8 0.0 3.9 7.3 0.0 2.8 2 0 0 2 2 2 2 ATPase domain predominantly from Archaea Pox_A32 PF04665.12 CRK27878.1 - 0.0032 17.0 0.0 2.9 7.3 0.0 2.2 2 0 0 2 2 2 2 Poxvirus A32 protein NACHT PF05729.12 CRK27878.1 - 0.0041 17.0 0.7 12 5.8 0.1 4.0 4 0 0 4 4 4 0 NACHT domain AAA_29 PF13555.6 CRK27878.1 - 0.0042 16.8 0.0 4.6 7.1 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain DAP3 PF10236.9 CRK27878.1 - 0.0048 16.1 0.1 3.3 6.8 0.0 2.3 2 0 0 2 2 2 2 Mitochondrial ribosomal death-associated protein 3 NB-ARC PF00931.22 CRK27878.1 - 0.005 16.0 0.1 3.9 6.6 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain AAA_7 PF12775.7 CRK27878.1 - 0.0054 16.3 0.1 4 6.9 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region ATPase PF06745.13 CRK27878.1 - 0.0056 16.1 0.1 4.8 6.5 0.0 2.7 2 0 0 2 2 2 0 KaiC ResIII PF04851.15 CRK27878.1 - 0.0058 16.7 1.5 11 5.9 0.1 4.1 4 0 0 4 4 4 0 Type III restriction enzyme, res subunit cobW PF02492.19 CRK27878.1 - 0.0096 15.5 2.6 4.4 6.9 0.1 3.1 3 0 0 3 3 3 2 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 CRK27878.1 - 0.015 15.5 0.8 12 6.0 0.1 3.4 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 CRK27878.1 - 0.021 14.7 0.0 9.2 6.1 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase MobB PF03205.14 CRK27878.1 - 0.022 14.7 0.1 12 5.8 0.0 2.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B TrwB_AAD_bind PF10412.9 CRK27878.1 - 0.035 13.0 0.5 7.2 5.4 0.1 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain FtsK_SpoIIIE PF01580.18 CRK27878.1 - 0.04 13.3 4.3 5 6.4 0.0 3.4 4 0 0 4 4 4 0 FtsK/SpoIIIE family PGBA_N PF15436.6 CRK27878.1 - 0.047 13.3 0.0 13 5.4 0.0 2.3 2 0 0 2 2 2 0 Plasminogen-binding protein pgbA N-terminal AAA_24 PF13479.6 CRK27878.1 - 0.081 12.6 1.6 12 5.5 0.1 2.6 2 0 0 2 2 2 0 AAA domain Glycos_transf_N PF04413.16 CRK27878.1 - 0.084 12.5 0.0 17 5.0 0.0 2.4 2 0 0 2 2 2 0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) DUF4090 PF13319.6 CRK27878.1 - 0.11 12.7 2.3 24 5.3 0.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4090) Rad17 PF03215.15 CRK27878.1 - 0.12 12.2 0.0 22 4.9 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain SAM_4 PF18017.1 CRK27878.1 - 0.16 12.0 0.1 35 4.5 0.0 2.8 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) LicD PF04991.13 CRK27878.1 - 0.19 11.9 11.7 1.5 8.9 2.4 2.9 2 0 0 2 2 2 0 LicD family DUF4162 PF13732.6 CRK27878.1 - 0.21 12.4 2.3 1.1e+02 3.6 0.0 4.5 4 0 0 4 4 3 0 Domain of unknown function (DUF4162) Thump_like PF18096.1 CRK27878.1 - 0.5 10.3 6.0 7.7 6.5 0.3 3.4 3 0 0 3 3 2 0 THUMP domain-like IATP PF04568.12 CRK27878.1 - 0.79 10.2 12.6 7.7 7.0 0.4 4.6 4 0 0 4 4 4 0 Mitochondrial ATPase inhibitor, IATP Cucumo_2B PF03263.13 CRK27878.1 - 3.5 8.1 19.8 20 5.7 5.9 3.6 2 0 0 2 2 2 0 Cucumovirus protein 2B TORC_N PF12884.7 CRK27878.1 - 4 8.3 11.6 1.2e+02 3.5 0.3 4.6 2 2 2 4 4 4 0 Transducer of regulated CREB activity, N terminus DnaJ PF00226.31 CRK27879.1 - 1.5e-26 92.3 2.9 2.5e-26 91.6 2.9 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 CRK27879.1 - 1.2e-25 90.4 0.0 1.7e-25 89.8 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 CRK27879.1 - 3.3e-14 53.0 16.5 5.2e-14 52.4 16.5 1.3 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 CRK27879.1 - 0.00092 19.2 8.9 0.046 13.7 1.3 2.2 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 CRK27879.1 - 0.0024 17.8 8.6 0.37 10.8 1.1 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein TackOD1 PF18551.1 CRK27879.1 - 0.16 11.6 7.1 0.45 10.1 0.5 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 zinc-ribbons_6 PF07191.12 CRK27879.1 - 9.9 6.2 11.4 29 4.7 2.2 2.2 1 1 1 2 2 2 0 zinc-ribbons Pro-MCH PF05824.12 CRK27880.1 - 0.16 11.9 0.3 1.2 9.1 0.3 2.6 1 0 0 1 1 1 0 Pro-melanin-concentrating hormone (Pro-MCH) NPC1_N PF16414.5 CRK27881.1 - 4.5e-09 36.2 6.2 5.4e-09 36.0 6.2 1.1 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus DUF4190 PF13828.6 CRK27881.1 - 0.0046 16.7 0.1 0.0061 16.3 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4190) DUF4381 PF14316.6 CRK27881.1 - 0.049 13.9 0.0 0.057 13.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Glyco_hydro_15 PF00723.21 CRK27882.1 - 3.6e-08 32.6 0.1 0.00051 18.9 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolases family 15 S-AdoMet_synt_C PF02773.16 CRK27883.1 - 9e-19 67.8 0.0 1.1e-18 67.5 0.0 1.0 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain DUF3237 PF11578.8 CRK27892.1 - 7.6e-27 94.0 0.0 8.8e-27 93.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Amidase PF01425.21 CRK27894.1 - 1.6e-87 294.3 0.0 5.4e-87 292.6 0.0 1.7 1 1 0 1 1 1 1 Amidase NmrA PF05368.13 CRK27896.1 - 1.5e-17 64.0 0.6 1.8e-17 63.7 0.6 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 CRK27896.1 - 1.8e-14 54.1 0.1 3.4e-14 53.1 0.1 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 CRK27896.1 - 2.6e-07 30.4 0.1 5.7e-05 22.7 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CRK27896.1 - 3.2e-05 23.1 0.1 7.2e-05 21.9 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.17 CRK27896.1 - 0.00013 22.5 0.7 0.00044 20.8 0.3 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent KR PF08659.10 CRK27896.1 - 0.00022 21.2 0.0 0.00038 20.4 0.0 1.3 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 CRK27896.1 - 0.00036 20.1 0.0 0.038 13.4 0.0 2.2 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase DapB_N PF01113.20 CRK27896.1 - 0.061 13.4 1.4 0.14 12.3 0.4 2.0 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus TrkA_N PF02254.18 CRK27896.1 - 0.09 13.0 0.2 0.19 12.0 0.2 1.5 1 0 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.20 CRK27896.1 - 0.13 12.3 0.1 0.46 10.5 0.1 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Zn_clus PF00172.18 CRK27899.1 - 1.3e-09 38.1 12.5 2.7e-09 37.0 12.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 CRK27899.1 - 6.8e-08 31.9 0.0 1.2e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain SLAC1 PF03595.17 CRK27901.1 - 7.9e-83 278.4 40.3 9.1e-83 278.2 40.3 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel TFR_dimer PF04253.15 CRK27903.1 - 6.9e-23 81.0 0.0 1.3e-22 80.2 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 CRK27903.1 - 2.5e-18 66.5 0.0 4e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 CRK27903.1 - 6e-13 48.6 2.1 8.3e-12 45.0 2.1 2.7 1 1 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 CRK27903.1 - 0.036 13.8 0.0 0.14 11.8 0.0 1.9 2 0 0 2 2 2 0 Peptidase family M20/M25/M40 MFS_1 PF07690.16 CRK27906.1 - 7.9e-14 51.3 36.5 9e-13 47.9 36.0 2.4 1 1 2 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK27906.1 - 4.4e-05 22.5 4.1 4.4e-05 22.5 4.1 2.6 2 1 1 3 3 3 1 Sugar (and other) transporter zf-CSL PF05207.13 CRK27908.1 - 8.4e-23 79.9 0.8 1.1e-22 79.6 0.8 1.1 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.10 CRK27908.1 - 0.0022 18.0 0.3 0.0035 17.4 0.3 1.3 1 0 0 1 1 1 1 Zinc ribbon domain Prok-RING_1 PF14446.6 CRK27908.1 - 0.22 11.5 2.9 0.44 10.5 2.9 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 ABC_membrane_2 PF06472.15 CRK27910.1 - 1.1e-102 343.1 1.6 1.7e-102 342.4 1.6 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 CRK27910.1 - 1.8e-19 70.6 0.0 4e-19 69.5 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CRK27910.1 - 0.0003 20.7 0.0 0.00072 19.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CRK27910.1 - 0.01 16.3 0.0 0.11 13.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 CRK27910.1 - 0.067 12.9 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.19 CRK27910.1 - 0.077 12.4 0.5 0.27 10.7 0.0 2.1 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain RuvB_N PF05496.12 CRK27910.1 - 0.097 12.4 0.0 0.51 10.1 0.0 2.1 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Cloacin_immun PF03513.14 CRK27910.1 - 0.11 12.8 0.0 0.65 10.4 0.0 2.2 2 0 0 2 2 2 0 Cloacin immunity protein AAA_16 PF13191.6 CRK27910.1 - 0.11 12.8 0.1 0.62 10.4 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Mg_chelatase PF01078.21 CRK27910.1 - 0.15 11.4 0.1 0.63 9.4 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 CRK27910.1 - 0.16 11.9 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain HSP70 PF00012.20 CRK27912.1 - 2.6e-10 39.2 0.0 7.9e-08 30.9 0.0 2.5 2 1 0 2 2 2 2 Hsp70 protein CENP-F_leu_zip PF10473.9 CRK27914.1 - 0.0072 16.4 5.3 0.014 15.4 5.3 1.4 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 UPF0242 PF06785.11 CRK27914.1 - 0.05 13.7 4.5 0.13 12.3 4.5 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF5452 PF17533.2 CRK27914.1 - 0.065 13.3 1.5 0.88 9.6 0.4 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5452) DMPK_coil PF08826.10 CRK27914.1 - 0.11 12.6 4.4 0.37 10.9 4.4 1.8 1 0 0 1 1 1 0 DMPK coiled coil domain like IBR PF01485.21 CRK27916.1 - 6.5e-15 55.1 29.2 6e-10 39.2 1.6 4.5 4 0 0 4 4 4 3 IBR domain, a half RING-finger domain zf-ribbon_3 PF13248.6 CRK27916.1 - 0.41 10.1 4.4 19 4.8 0.1 3.9 3 0 0 3 3 3 0 zinc-ribbon domain Cupin_2 PF07883.11 CRK27917.1 - 1.6e-06 27.7 0.4 2.7e-06 27.0 0.4 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 CRK27917.1 - 1e-05 25.2 0.1 1.4e-05 24.7 0.1 1.2 1 0 0 1 1 1 1 Cupin Cupin_6 PF12852.7 CRK27917.1 - 0.0042 16.8 0.1 0.0055 16.4 0.1 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 CRK27917.1 - 0.022 14.6 0.1 0.032 14.1 0.1 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain ARD PF03079.14 CRK27917.1 - 0.074 13.2 0.0 0.094 12.9 0.0 1.3 1 0 0 1 1 1 0 ARD/ARD' family 4HBT_3 PF13622.6 CRK27918.1 - 3.3e-47 161.9 0.4 3.8e-47 161.7 0.4 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily AAA PF00004.29 CRK27919.1 - 9.7e-19 68.1 0.0 1.8e-18 67.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CRK27919.1 - 0.00017 22.0 0.0 0.0027 18.1 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 CRK27919.1 - 0.0014 18.4 0.0 0.0033 17.2 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CRK27919.1 - 0.011 16.0 0.0 0.041 14.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 CRK27919.1 - 0.03 14.3 0.1 0.13 12.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.6 CRK27919.1 - 0.068 13.6 0.0 0.24 11.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain Imm5 PF14423.6 CRK27919.1 - 0.068 13.4 3.5 0.077 13.2 2.2 1.7 2 0 0 2 2 2 0 Immunity protein Imm5 AAA_2 PF07724.14 CRK27919.1 - 0.071 13.2 0.0 1.1 9.3 0.0 2.4 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 CRK27919.1 - 0.1 13.2 1.9 0.28 11.7 0.0 2.7 3 0 0 3 3 2 0 AAA domain AIM3 PF17096.5 CRK27919.1 - 0.11 13.5 1.3 0.23 12.4 1.3 1.5 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 AAA_11 PF13086.6 CRK27919.1 - 0.11 12.2 1.2 0.89 9.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain BSP_II PF05432.11 CRK27919.1 - 0.26 10.9 13.8 0.086 12.5 10.9 1.6 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) RXT2_N PF08595.11 CRK27919.1 - 0.38 10.8 5.1 0.82 9.7 5.1 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal Mg_chelatase PF01078.21 CRK27919.1 - 0.56 9.5 2.2 1.8 7.9 0.1 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI PGA2 PF07543.12 CRK27919.1 - 0.81 9.7 7.1 1.7 8.7 7.1 1.5 1 0 0 1 1 1 0 Protein trafficking PGA2 FAM176 PF14851.6 CRK27919.1 - 1.4 8.6 7.0 2.8 7.6 7.0 1.4 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.12 CRK27919.1 - 3.4 6.9 12.3 5 6.4 12.3 1.2 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 CRK27919.1 - 3.4 5.8 8.8 4.5 5.4 8.8 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 CRK27919.1 - 7.7 4.7 7.6 11 4.2 7.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Glyco_hydro_35 PF01301.19 CRK27921.1 - 6.2e-90 302.0 0.5 1e-89 301.3 0.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.9 CRK27921.1 - 2.9e-58 196.6 1.2 4.6e-58 196.0 1.2 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.6 CRK27921.1 - 2.8e-51 172.9 0.9 1.8e-31 109.1 0.1 2.9 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.6 CRK27921.1 - 3e-21 74.8 0.0 1.5e-20 72.5 0.0 2.2 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Cellulase PF00150.18 CRK27921.1 - 0.002 17.6 0.1 0.0036 16.8 0.1 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyoxalase PF00903.25 CRK27922.1 - 0.011 15.9 0.0 0.12 12.5 0.0 2.0 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily UDPGT PF00201.18 CRK27923.1 - 0.00051 19.0 0.0 0.00071 18.5 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.11 CRK27923.1 - 0.026 14.9 0.2 0.54 10.6 0.0 3.0 4 1 0 4 4 4 0 Autophagy-related protein C terminal domain polyprenyl_synt PF00348.17 CRK27927.1 - 1.2e-25 90.0 0.2 1.4e-25 89.9 0.2 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase HEPPP_synt_1 PF07307.11 CRK27927.1 - 0.05 13.2 0.0 0.054 13.1 0.0 1.2 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 TRAM_LAG1_CLN8 PF03798.16 CRK27928.1 - 1.8e-38 132.3 12.9 2.1e-38 132.1 12.9 1.1 1 0 0 1 1 1 1 TLC domain Bax1-I PF01027.20 CRK27929.1 - 7.8e-52 176.1 25.1 9e-52 175.9 25.1 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF5504 PF17608.2 CRK27929.1 - 1.1 9.4 10.7 0.17 12.0 4.8 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5504) DUF4131 PF13567.6 CRK27929.1 - 7.6 6.1 10.1 17 5.0 3.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Septin PF00735.18 CRK27930.1 - 5.3e-87 291.7 0.3 9.5e-52 176.0 0.0 2.4 3 0 0 3 3 3 2 Septin MMR_HSR1 PF01926.23 CRK27930.1 - 9.8e-05 22.4 0.0 0.00024 21.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 CRK27930.1 - 0.0069 16.4 4.0 2 8.5 0.0 3.1 2 1 1 3 3 3 2 Dynamin family RsgA_GTPase PF03193.16 CRK27930.1 - 0.024 14.5 0.6 0.024 14.5 0.6 2.1 2 1 0 2 2 2 0 RsgA GTPase AAA_23 PF13476.6 CRK27930.1 - 0.053 14.0 3.8 13 6.2 3.5 2.1 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 CRK27930.1 - 0.068 13.4 0.3 0.45 10.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.27 CRK27930.1 - 0.098 12.2 0.0 0.098 12.2 0.0 1.7 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 CRK27930.1 - 0.11 12.7 0.4 0.21 11.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain TetR_C_36 PF18598.1 CRK27930.1 - 0.12 12.3 1.1 4.9 7.1 0.6 2.3 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain WD40 PF00400.32 CRK27931.1 - 0.0082 17.0 0.1 0.081 13.8 0.0 2.8 3 0 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK27931.1 - 0.12 12.7 0.0 0.31 11.3 0.0 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain RRM_1 PF00076.22 CRK27932.1 - 6.4e-08 32.3 0.9 1.5e-06 28.0 0.0 2.5 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CRK27932.1 - 0.024 14.8 0.2 0.086 13.0 0.2 2.0 1 1 0 1 1 1 0 RNA recognition motif Tenui_NS3 PF05310.12 CRK27932.1 - 0.068 13.3 1.9 0.1 12.7 1.9 1.2 1 0 0 1 1 1 0 Tenuivirus movement protein DLIC PF05783.11 CRK27933.1 - 6e-29 101.2 0.0 2.3e-27 96.0 0.0 2.5 2 1 0 2 2 2 2 Dynein light intermediate chain (DLIC) Glyoxal_oxid_N PF07250.11 CRK27933.1 - 0.2 10.8 0.0 0.33 10.1 0.0 1.2 1 0 0 1 1 1 0 Glyoxal oxidase N-terminus Thioredox_DsbH PF03190.15 CRK27934.1 - 6e-59 198.6 0.0 9.9e-59 197.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 CRK27934.1 - 2.7e-06 27.4 0.0 6.3e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Sigma70_r4 PF04545.16 CRK27934.1 - 0.023 14.2 0.2 0.071 12.7 0.2 1.9 1 0 0 1 1 1 0 Sigma-70, region 4 MFS_1 PF07690.16 CRK27935.1 - 1.4e-20 73.6 29.9 1.4e-20 73.6 29.9 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily YesK PF14150.6 CRK27935.1 - 0.037 14.2 0.7 0.39 10.9 0.7 2.7 2 0 0 2 2 2 0 YesK-like protein Lambda_Kil PF06301.11 CRK27935.1 - 0.11 12.1 0.1 0.27 10.8 0.1 1.6 1 0 0 1 1 1 0 Bacteriophage lambda Kil protein DIOX_N PF14226.6 CRK27936.1 - 1e-20 74.7 0.0 6e-20 72.2 0.0 2.1 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 CRK27936.1 - 2e-10 41.1 0.0 3.2e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF2299 PF10061.9 CRK27938.1 - 0.25 11.1 0.0 0.37 10.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2299) ABC_tran PF00005.27 CRK27939.1 - 7e-30 104.3 0.0 1.5e-29 103.2 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 CRK27939.1 - 7.6e-19 68.4 0.0 1.1e-18 67.9 0.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region Homeobox_KN PF05920.11 CRK27939.1 - 1.7e-13 50.2 1.1 3.3e-13 49.3 1.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 CRK27939.1 - 3.6e-07 29.9 0.5 8.3e-07 28.8 0.5 1.6 1 0 0 1 1 1 1 Homeodomain SMC_N PF02463.19 CRK27939.1 - 0.0088 15.5 0.0 0.03 13.8 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 CRK27939.1 - 0.035 14.3 0.6 0.82 10.0 0.6 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit HTH_Tnp_Tc5 PF03221.16 CRK27939.1 - 0.057 13.5 0.1 0.16 12.1 0.1 1.7 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain UNC119_bdg PF15435.6 CRK27939.1 - 0.16 11.5 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 UNC119-binding protein C5orf30 homologue NAD_binding_10 PF13460.6 CRK27940.1 - 2.7e-06 27.4 0.7 0.0012 18.8 0.1 2.9 1 1 1 2 2 2 2 NAD(P)H-binding NmrA PF05368.13 CRK27940.1 - 3.7e-06 26.7 3.2 8.9e-05 22.1 0.0 2.1 1 1 0 2 2 2 2 NmrA-like family Epimerase PF01370.21 CRK27940.1 - 0.04 13.4 0.0 0.12 11.8 0.0 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family adh_short PF00106.25 CRK27940.1 - 0.31 10.5 2.4 0.9 9.0 1.9 1.8 1 1 1 2 2 2 0 short chain dehydrogenase CMS1 PF14617.6 CRK27942.1 - 2.9e-74 249.6 0.9 4.9e-60 203.0 0.1 2.0 1 1 1 2 2 2 2 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 CRK27942.1 - 1.6e-05 24.7 0.0 2.4e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Glyco_hydro_17 PF00332.18 CRK27943.1 - 8.2e-34 117.6 0.4 4e-33 115.3 0.4 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 Ank_4 PF13637.6 CRK27947.1 - 2.4e-08 34.4 2.4 0.21 12.2 0.0 5.8 5 1 1 6 6 6 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CRK27947.1 - 5.4e-07 30.1 0.0 0.65 10.6 0.0 4.1 3 2 1 4 4 4 3 Ankyrin repeats (3 copies) F-box PF00646.33 CRK27947.1 - 0.0091 15.9 1.3 0.017 15.0 0.2 2.1 2 0 0 2 2 2 1 F-box domain UPF0139 PF03669.13 CRK27948.1 - 3e-08 33.4 0.1 0.0024 17.7 0.0 2.4 2 1 0 2 2 2 2 Uncharacterised protein family (UPF0139) Yip1 PF04893.17 CRK27948.1 - 0.0002 21.1 0.2 0.0069 16.1 0.2 2.1 1 1 1 2 2 2 1 Yip1 domain PSII_Pbs27 PF13326.6 CRK27948.1 - 0.018 15.3 0.0 2.6 8.4 0.0 2.2 1 1 1 2 2 2 0 Photosystem II Pbs27 Med12 PF09497.10 CRK27949.1 - 2e-36 124.1 1.4 1.3e-26 92.6 0.2 3.1 2 0 0 2 2 2 2 Transcription mediator complex subunit Med12 Microvir_lysis PF04517.12 CRK27949.1 - 8.6e-05 22.4 0.5 0.69 9.9 0.0 2.9 2 0 0 2 2 2 2 Microvirus lysis protein (E), C terminus HTH_9 PF08221.11 CRK27949.1 - 0.023 14.8 0.1 98 3.2 0.0 4.5 4 0 0 4 4 4 0 RNA polymerase III subunit RPC82 helix-turn-helix domain GyrB_insert PF18053.1 CRK27949.1 - 0.027 14.3 0.1 7.4 6.4 0.0 2.6 2 0 0 2 2 2 0 DNA gyrase B subunit insert domain PhrC_PhrF PF11131.8 CRK27949.1 - 0.03 13.9 0.7 14 5.4 0.1 3.1 2 0 0 2 2 2 0 Rap-phr extracellular signalling DUF1977 PF09320.11 CRK27949.1 - 0.071 13.4 0.0 14 6.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1977) TAN PF11640.8 CRK27949.1 - 0.079 13.1 5.9 5.4 7.1 0.1 3.6 5 0 0 5 5 5 0 Telomere-length maintenance and DNA damage repair LST1 PF05083.13 CRK27949.1 - 0.21 11.9 0.4 1.1 9.6 0.1 2.3 2 0 0 2 2 2 0 LST-1 protein YLP PF02757.17 CRK27949.1 - 7.5 6.9 6.4 53 4.3 0.7 3.2 2 0 0 2 2 2 0 YLP motif S1-P1_nuclease PF02265.16 CRK27952.1 - 9.2e-69 232.1 0.0 1.1e-68 231.8 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease PQ-loop PF04193.14 CRK27953.1 - 7.3e-37 125.0 6.4 1.3e-19 69.7 0.1 4.0 4 1 1 5 5 5 2 PQ loop repeat ER_lumen_recept PF00810.18 CRK27953.1 - 0.038 14.8 1.9 0.71 10.7 0.2 2.8 2 1 1 3 3 3 0 ER lumen protein retaining receptor CD99L2 PF12301.8 CRK27953.1 - 0.2 12.0 0.1 34 4.7 0.0 2.7 2 2 0 2 2 2 0 CD99 antigen like protein 2 WW_1 PF18507.1 CRK27953.1 - 0.25 11.1 3.4 12 5.7 0.3 2.4 2 0 0 2 2 2 0 WW domain DMAP_binding PF06464.11 CRK27953.1 - 3.7 8.4 5.6 31 5.4 0.4 2.4 2 0 0 2 2 2 0 DMAP1-binding Domain Pkinase PF00069.25 CRK27956.1 - 4e-41 141.1 0.0 5.2e-41 140.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK27956.1 - 1e-23 84.0 0.0 1.3e-23 83.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CRK27956.1 - 0.00024 20.5 0.0 0.00031 20.2 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CRK27956.1 - 0.0021 18.0 0.1 0.0055 16.7 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 CRK27956.1 - 0.003 17.0 0.0 0.0046 16.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CRK27956.1 - 0.017 14.1 0.0 0.024 13.6 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 CRK27956.1 - 0.037 12.8 0.0 0.037 12.8 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Choline_kinase PF01633.20 CRK27956.1 - 0.16 11.5 0.0 0.26 10.8 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase zf-C2H2_aberr PF17017.5 CRK27959.1 - 0.025 14.7 6.1 0.098 12.8 0.0 3.2 3 0 0 3 3 3 0 Aberrant zinc-finger zf-C2H2_4 PF13894.6 CRK27959.1 - 0.039 14.8 35.6 6.4 7.9 0.1 8.9 8 0 0 8 8 8 0 C2H2-type zinc finger YdjO PF14169.6 CRK27959.1 - 0.11 12.2 2.6 1.1 9.0 0.1 3.3 3 0 0 3 3 3 0 Cold-inducible protein YdjO zf-Di19 PF05605.12 CRK27959.1 - 0.89 9.9 11.3 0.088 13.1 1.1 3.7 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 CRK27959.1 - 4.2 7.2 21.5 0.076 12.8 0.2 5.5 4 1 0 4 4 4 0 C2H2-type zinc-finger domain AATase PF07247.12 CRK27961.1 - 4.6e-12 45.3 0.0 1.3e-11 43.8 0.0 1.6 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.20 CRK27961.1 - 0.0043 15.8 0.0 0.013 14.2 0.0 1.6 2 0 0 2 2 2 1 Condensation domain WES_acyltransf PF03007.16 CRK27961.1 - 0.0084 15.9 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain RSN1_7TM PF02714.15 CRK27963.1 - 2.4e-78 263.2 17.5 4.5e-78 262.3 17.5 1.4 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 CRK27963.1 - 8.8e-39 132.8 3.7 2.2e-38 131.5 3.7 1.7 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 CRK27963.1 - 2.8e-34 118.9 0.5 3.7e-27 95.7 0.1 2.2 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter TMF_TATA_bd PF12325.8 CRK27963.1 - 0.13 12.4 0.1 0.3 11.3 0.1 1.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding TPR_19 PF14559.6 CRK27965.1 - 5.5e-05 23.6 4.4 0.016 15.7 0.0 3.2 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CRK27965.1 - 0.0069 16.6 0.0 0.017 15.3 0.0 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 CRK27965.1 - 0.037 14.7 0.6 33 5.4 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat PBP_sp32 PF07222.12 CRK27965.1 - 0.059 12.8 0.0 0.091 12.2 0.0 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Histidinol_dh PF00815.20 CRK27966.1 - 1.6e-134 449.0 0.1 1.9e-134 448.8 0.1 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase DNA_pol_phi PF04931.13 CRK27967.1 - 4.9 5.1 8.2 0.26 9.3 3.1 1.4 2 0 0 2 2 2 0 DNA polymerase phi CPSF_A PF03178.15 CRK27969.1 - 1.9e-36 126.0 0.0 2.1e-36 125.9 0.0 1.0 1 0 0 1 1 1 1 CPSF A subunit region PapC_C PF13953.6 CRK27969.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 PapC C-terminal domain PHO4 PF01384.20 CRK27970.1 - 3.7e-28 98.5 9.0 4.1e-28 98.4 9.0 1.0 1 0 0 1 1 1 1 Phosphate transporter family Helicase_C PF00271.31 CRK27974.1 - 5.3e-28 97.6 0.0 1.3e-27 96.3 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Filament PF00038.21 CRK27976.1 - 0.00047 19.9 2.5 0.00059 19.5 2.5 1.1 1 0 0 1 1 1 1 Intermediate filament protein TSKS PF15358.6 CRK27976.1 - 0.001 17.5 4.3 0.0013 17.2 4.3 1.1 1 0 0 1 1 1 1 Testis-specific serine kinase substrate WD40_alt PF14077.6 CRK27976.1 - 0.03 14.2 0.5 0.24 11.3 0.0 2.2 2 0 0 2 2 2 0 Alternative WD40 repeat motif DUF2894 PF11445.8 CRK27976.1 - 0.15 12.5 11.7 0.5 10.8 12.4 1.5 2 0 0 2 2 1 0 Protein of unknown function (DUF2894) Use1 PF09753.9 CRK27976.1 - 0.18 11.5 8.4 0.24 11.1 8.4 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 SPATA1_C PF15743.5 CRK27976.1 - 0.37 10.9 9.4 0.61 10.2 9.4 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated C-terminus ZapB PF06005.12 CRK27976.1 - 1.3 9.5 9.9 1.6 9.2 4.0 2.5 2 1 0 2 2 2 0 Cell division protein ZapB Atg14 PF10186.9 CRK27976.1 - 1.8 7.5 8.1 2.2 7.3 8.1 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 AAA_13 PF13166.6 CRK27976.1 - 2.4 6.7 7.8 3 6.4 7.8 1.1 1 0 0 1 1 1 0 AAA domain Spc7 PF08317.11 CRK27976.1 - 5.7 5.7 10.8 8 5.2 10.8 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein HALZ PF02183.18 CRK27976.1 - 5.7 7.2 6.4 14 6.0 0.1 2.8 3 0 0 3 3 3 0 Homeobox associated leucine zipper SKG6 PF08693.10 CRK27977.1 - 2.6 7.5 6.9 5.3 6.5 6.9 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Glyco_transf_15 PF01793.16 CRK27980.1 - 4.6e-41 141.1 0.0 4.9e-27 95.0 0.0 3.0 2 1 0 2 2 2 2 Glycolipid 2-alpha-mannosyltransferase p450 PF00067.22 CRK27982.1 - 1e-33 116.8 0.0 1.4e-33 116.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 PSII_BNR PF14870.6 CRK27982.1 - 3.5e-08 33.1 3.3 0.0077 15.5 0.0 3.5 2 1 1 4 4 4 2 Photosynthesis system II assembly factor YCF48 Sortilin-Vps10 PF15902.5 CRK27982.1 - 5.6e-06 25.4 0.0 0.0001 21.2 0.0 2.1 2 0 0 2 2 2 1 Sortilin, neurotensin receptor 3, BNR_2 PF13088.6 CRK27982.1 - 0.045 13.0 0.5 2.1 7.6 0.2 2.7 1 1 1 2 2 2 0 BNR repeat-like domain BNR PF02012.20 CRK27982.1 - 0.25 11.5 24.3 1.1 9.5 0.7 6.0 6 0 0 6 6 6 0 BNR/Asp-box repeat APH PF01636.23 CRK27988.1 - 1.5e-18 67.6 0.3 2.5e-18 66.9 0.3 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CRK27988.1 - 8.4e-05 22.3 0.0 0.00014 21.6 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 CRK27988.1 - 0.004 16.8 0.0 1.6 8.3 0.0 2.4 2 0 0 2 2 2 2 RIO1 family Pkinase PF00069.25 CRK27988.1 - 0.1 11.9 0.0 0.66 9.3 0.0 2.0 2 0 0 2 2 2 0 Protein kinase domain Polyketide_cyc2 PF10604.9 CRK27992.1 - 2.1e-07 31.3 0.0 2.4e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF4521 PF15021.6 CRK27992.1 - 0.14 12.1 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4521) Rhomboid PF01694.22 CRK27999.1 - 5.8e-14 52.3 2.0 7.3e-14 52.0 2.0 1.1 1 0 0 1 1 1 1 Rhomboid family zf-C4pol PF14260.6 CRK27999.1 - 2.8e-10 40.5 6.0 4.1e-10 40.0 6.0 1.2 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta Amidohydro_1 PF01979.20 CRK28004.1 - 1.2e-10 41.3 0.1 1.2e-10 41.3 0.1 1.0 1 0 0 1 1 1 1 Amidohydrolase family Pkinase PF00069.25 CRK28005.1 - 7.7e-59 199.2 0.0 1e-58 198.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK28005.1 - 6.9e-35 120.6 0.0 1e-34 120.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 CRK28005.1 - 1e-05 25.6 0.1 0.00074 19.7 0.0 3.0 3 0 0 3 3 3 1 POLO box duplicated region Kdo PF06293.14 CRK28005.1 - 0.00075 18.9 0.0 0.0017 17.8 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CRK28005.1 - 0.02 13.7 0.1 0.02 13.7 0.1 2.0 2 0 0 2 2 2 0 Fungal protein kinase Kinase-like PF14531.6 CRK28005.1 - 0.069 12.4 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Sel1 PF08238.12 CRK28006.1 - 2.2e-39 133.0 27.5 4.3e-06 27.2 0.2 7.4 7 0 0 7 7 7 7 Sel1 repeat Chitin_synth_2 PF03142.15 CRK28007.1 - 1.5e-279 928.0 1.2 2e-279 927.6 1.2 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 CRK28007.1 - 2.1e-14 53.9 4.7 7.7e-14 52.1 4.7 2.0 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 CRK28007.1 - 5.5e-10 39.5 0.1 3.2e-09 37.0 0.0 2.2 3 0 0 3 3 3 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 CRK28007.1 - 0.00054 19.5 0.0 0.0069 15.9 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Cyt-b5 PF00173.28 CRK28007.1 - 0.0034 17.5 0.0 2.7 8.2 0.0 2.7 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.26 CRK28007.1 - 0.011 15.6 0.0 0.079 12.8 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 2 DUF2415 PF10313.9 CRK28008.1 - 0.035 14.0 0.0 0.21 11.5 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) ANAPC4_WD40 PF12894.7 CRK28008.1 - 0.041 14.2 0.1 18 5.7 0.0 3.3 2 1 2 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CRK28008.1 - 1.3 10.1 6.2 1.3 10.0 1.6 3.4 3 0 0 3 3 3 0 WD domain, G-beta repeat Glyco_hydro_17 PF00332.18 CRK28009.1 - 0.12 11.9 0.2 1.9 8.0 0.1 2.1 2 0 0 2 2 2 0 Glycosyl hydrolases family 17 Glyco_hydro_72 PF03198.14 CRK28009.1 - 0.19 10.9 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 Glucanosyltransferase Sortilin-Vps10 PF15902.5 CRK28010.1 - 1.7e-293 973.1 21.2 1.6e-148 495.2 8.4 2.1 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 CRK28010.1 - 1.2e-88 295.9 29.1 5.1e-47 160.4 8.7 2.9 3 0 0 3 3 3 2 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 CRK28010.1 - 2e-08 33.0 38.9 2.4 8.5 0.0 11.1 10 0 0 10 10 10 4 BNR/Asp-box repeat PSII_BNR PF14870.6 CRK28010.1 - 0.0011 18.3 5.1 0.097 11.9 0.0 4.5 4 1 0 4 4 4 1 Photosynthesis system II assembly factor YCF48 DUF2561 PF10812.8 CRK28010.1 - 0.0035 17.4 0.3 0.0064 16.6 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2561) DUF2167 PF09935.9 CRK28010.1 - 0.076 12.2 0.4 0.19 10.9 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2167) preSET_CXC PF18264.1 CRK28010.1 - 0.49 10.9 8.3 3.7 8.1 0.9 2.8 2 0 0 2 2 2 0 CXC domain BNR_6 PF15899.5 CRK28010.1 - 1.8 8.9 22.2 7.3 7.0 0.0 7.8 8 0 0 8 8 8 0 BNR-Asp box repeat Sortilin-Vps10 PF15902.5 CRK28012.1 - 0.088 11.6 0.0 0.099 11.4 0.0 1.2 1 0 0 1 1 1 0 Sortilin, neurotensin receptor 3, Mago-bind PF09282.10 CRK28013.1 - 1.4e-15 56.9 1.6 3.6e-15 55.5 1.6 1.8 1 0 0 1 1 1 1 Mago binding Nucleo_P87 PF07267.11 CRK28013.1 - 2.8 6.7 5.0 3.2 6.5 5.0 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Mago-bind PF09282.10 CRK28014.1 - 1.3e-15 56.9 1.6 2.7e-15 55.9 1.6 1.6 1 0 0 1 1 1 1 Mago binding UCR_UQCRX_QCR9 PF05365.12 CRK28015.1 - 2.4e-20 72.2 1.5 3.3e-20 71.8 1.5 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Ribonuc_L-PSP PF01042.21 CRK28016.1 - 8.9e-40 135.5 0.0 1.2e-39 135.0 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP PMT PF02366.18 CRK28017.1 - 1.8e-85 286.5 16.3 2.1e-85 286.3 16.3 1.0 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase RAMP4 PF06624.12 CRK28017.1 - 0.0032 17.5 4.2 0.84 9.7 0.2 2.8 3 0 0 3 3 3 2 Ribosome associated membrane protein RAMP4 DHHC PF01529.20 CRK28017.1 - 2.4 8.3 6.6 44 4.2 6.6 2.5 1 1 0 1 1 1 0 DHHC palmitoyltransferase Sortilin-Vps10 PF15902.5 CRK28018.1 - 1.1e-57 195.9 4.2 1.4e-57 195.5 4.2 1.1 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 CRK28018.1 - 3.2e-24 86.2 0.8 5.6e-24 85.4 0.8 1.3 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 CRK28018.1 - 0.055 13.5 9.9 0.43 10.8 0.1 4.4 4 0 0 4 4 4 0 BNR/Asp-box repeat EpuA PF11772.8 CRK28018.1 - 0.057 13.1 0.6 0.11 12.1 0.6 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta PhoLip_ATPase_C PF16212.5 CRK28020.1 - 3.4e-20 72.8 4.9 3.6e-20 72.8 4.9 1.0 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal PBP_N PF17093.5 CRK28020.1 - 0.6 10.4 2.0 0.84 9.9 2.0 1.3 1 0 0 1 1 1 0 Penicillin-binding protein N-terminus ILVD_EDD PF00920.21 CRK28023.1 - 8.7e-23 80.7 0.0 1e-22 80.5 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family PAS_3 PF08447.12 CRK28024.1 - 7.3e-08 32.6 0.1 1.9e-07 31.3 0.0 1.7 2 0 0 2 2 2 1 PAS fold PAS PF00989.25 CRK28024.1 - 2.5e-06 27.5 0.0 8.4e-06 25.8 0.0 1.8 1 1 0 1 1 1 1 PAS fold PAS_9 PF13426.7 CRK28024.1 - 3e-06 27.4 0.0 1e-05 25.8 0.0 1.8 1 1 0 1 1 1 1 PAS domain PAS_4 PF08448.10 CRK28024.1 - 0.0012 19.0 0.3 0.033 14.4 0.3 2.2 1 1 0 1 1 1 1 PAS fold PAS_8 PF13188.7 CRK28024.1 - 0.0028 17.6 0.0 0.0052 16.8 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS_7 PF12860.7 CRK28024.1 - 0.0074 16.4 0.1 0.36 11.0 0.1 2.3 1 1 0 1 1 1 1 PAS fold DUF3563 PF12086.8 CRK28024.1 - 0.023 14.4 0.2 0.045 13.5 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3563) MFS_1 PF07690.16 CRK28025.1 - 5.4e-30 104.5 37.7 8.9e-30 103.8 37.7 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 CRK28025.1 - 1e-08 34.1 13.2 1.4e-08 33.7 13.2 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ketoacyl-synt PF00109.26 CRK28026.1 - 2.4e-71 240.3 0.0 4.7e-71 239.3 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 CRK28026.1 - 8.5e-46 156.5 0.1 1.4e-45 155.8 0.1 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 CRK28026.1 - 3.7e-41 141.0 0.5 6.5e-21 75.0 0.8 2.9 3 0 0 3 3 3 2 KR domain Acyl_transf_1 PF00698.21 CRK28026.1 - 1.3e-39 136.6 0.0 2.4e-39 135.7 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 CRK28026.1 - 1.1e-23 83.5 0.2 4.9e-12 45.9 0.1 2.8 1 1 1 2 2 2 2 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 CRK28026.1 - 1.8e-16 60.6 0.0 3.9e-16 59.5 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 CRK28026.1 - 7.2e-12 45.2 0.0 1.6e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase PP-binding PF00550.25 CRK28026.1 - 3.5e-06 27.3 0.0 9.4e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short_C2 PF13561.6 CRK28026.1 - 2.4e-05 24.0 0.0 0.0001 22.0 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ADH_zinc_N PF00107.26 CRK28026.1 - 0.00053 20.0 0.0 0.0059 16.6 0.0 2.8 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CRK28026.1 - 0.027 14.4 0.0 0.076 12.9 0.0 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain YjeF_N PF03853.15 CRK28026.1 - 0.054 13.4 0.1 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 YjeF-related protein N-terminus Thiolase_N PF00108.23 CRK28026.1 - 0.072 12.4 0.1 0.14 11.4 0.1 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain NAD_binding_3 PF03447.16 CRK28026.1 - 0.11 13.1 0.1 2.8 8.6 0.0 2.8 2 1 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain Flavi_M PF01004.19 CRK28027.1 - 0.016 15.0 0.5 0.032 14.0 0.5 1.5 1 0 0 1 1 1 0 Flavivirus envelope glycoprotein M MscS_TM PF12794.7 CRK28027.1 - 0.068 12.0 0.0 0.092 11.6 0.0 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 EGF_2 PF07974.13 CRK28028.1 - 9.1 6.8 8.9 17 5.9 8.9 1.4 1 0 0 1 1 1 0 EGF-like domain Cerato-platanin PF07249.12 CRK28030.1 - 1.3e-54 183.4 1.3 2.2e-54 182.6 1.3 1.4 1 0 0 1 1 1 1 Cerato-platanin GATA PF00320.27 CRK28031.1 - 2.5e-11 43.0 2.3 4.9e-11 42.0 2.3 1.5 1 0 0 1 1 1 1 GATA zinc finger GHMP_kinases_C PF08544.13 CRK28032.1 - 7.2e-11 42.3 0.0 0.00077 19.8 0.0 2.6 2 0 0 2 2 2 2 GHMP kinases C terminal GHMP_kinases_N PF00288.26 CRK28032.1 - 2.5e-09 37.2 0.0 2.5e-09 37.2 0.0 3.1 2 1 0 2 2 2 1 GHMP kinases N terminal domain Urb2 PF10441.9 CRK28032.1 - 0.13 12.1 0.0 22 4.9 0.0 2.2 2 0 0 2 2 2 0 Urb2/Npa2 family PsbQ PF05757.11 CRK28032.1 - 0.38 10.5 6.0 0.68 9.6 6.0 1.3 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) Plectin PF00681.20 CRK28034.1 - 0.13 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Plectin repeat WD40 PF00400.32 CRK28035.1 - 2.6e-17 62.9 10.6 0.00081 20.2 0.0 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat WD40_like PF17005.5 CRK28035.1 - 6.3e-06 25.7 0.0 1.4e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 WD40-like domain ANAPC4_WD40 PF12894.7 CRK28035.1 - 8.8e-05 22.7 0.0 1.1 9.6 0.0 4.4 1 1 4 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Folliculin PF11704.8 CRK28040.1 - 1.9e-60 203.9 1.5 4.8e-59 199.4 0.0 2.6 2 1 0 2 2 2 1 Vesicle coat protein involved in Golgi to plasma membrane transport AAA PF00004.29 CRK28041.1 - 2.2e-45 154.3 0.5 7.7e-45 152.6 0.0 2.1 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 CRK28041.1 - 1.3e-10 41.0 0.1 7.6e-10 38.6 0.0 2.2 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 CRK28041.1 - 2.2e-08 34.2 0.7 6.6e-08 32.6 0.1 2.2 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CRK28041.1 - 5.4e-08 33.1 0.0 1.1e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 CRK28041.1 - 3e-07 31.0 0.7 3.7e-05 24.2 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 CRK28041.1 - 4.4e-06 26.1 0.0 9.3e-06 25.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 CRK28041.1 - 3.2e-05 24.2 0.9 0.0088 16.3 0.1 2.7 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 CRK28041.1 - 0.00024 20.9 0.0 0.00073 19.3 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_3 PF17862.1 CRK28041.1 - 0.00036 20.3 0.0 0.00086 19.1 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_18 PF13238.6 CRK28041.1 - 0.00048 20.7 0.0 0.0013 19.3 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_28 PF13521.6 CRK28041.1 - 0.00064 20.0 0.0 0.0014 18.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 CRK28041.1 - 0.00089 18.8 0.1 0.0032 17.0 0.1 1.8 1 1 0 1 1 1 1 P-loop containing dynein motor region TIP49 PF06068.13 CRK28041.1 - 0.0014 17.9 0.0 0.0026 17.1 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain TsaE PF02367.17 CRK28041.1 - 0.0014 18.6 0.0 0.019 15.0 0.0 2.2 1 1 1 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 CRK28041.1 - 0.002 18.1 0.1 0.0078 16.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CRK28041.1 - 0.0021 18.4 0.0 0.0046 17.3 0.0 1.6 1 0 0 1 1 1 1 RNA helicase NTPase_1 PF03266.15 CRK28041.1 - 0.0044 17.0 0.0 0.015 15.2 0.0 1.9 2 0 0 2 2 2 1 NTPase NACHT PF05729.12 CRK28041.1 - 0.005 16.8 0.5 0.11 12.4 0.0 2.9 2 1 1 3 3 3 1 NACHT domain AAA_3 PF07726.11 CRK28041.1 - 0.0058 16.5 0.0 0.018 14.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 CRK28041.1 - 0.0062 16.3 1.3 0.013 15.2 0.1 2.2 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 CRK28041.1 - 0.0071 15.8 0.2 0.016 14.6 0.1 1.7 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 CRK28041.1 - 0.008 16.3 0.0 0.019 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 CRK28041.1 - 0.013 15.2 0.1 0.031 14.0 0.0 1.8 2 0 0 2 2 1 0 IstB-like ATP binding protein TniB PF05621.11 CRK28041.1 - 0.013 14.9 0.0 0.5 9.7 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein AAA_24 PF13479.6 CRK28041.1 - 0.022 14.5 0.2 0.055 13.2 0.2 1.8 1 1 0 1 1 1 0 AAA domain Viral_Hsp90 PF03225.14 CRK28041.1 - 0.034 12.7 0.0 0.053 12.0 0.0 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue Bac_DnaA PF00308.18 CRK28041.1 - 0.04 13.7 0.0 0.077 12.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein ATPase PF06745.13 CRK28041.1 - 0.04 13.3 1.2 0.56 9.5 0.0 2.5 3 0 0 3 3 3 0 KaiC AAA_11 PF13086.6 CRK28041.1 - 0.043 13.6 0.1 0.14 12.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 CRK28041.1 - 0.045 13.7 1.0 0.34 10.8 0.0 2.5 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea AFG1_ATPase PF03969.16 CRK28041.1 - 0.052 12.4 0.1 0.14 11.1 0.0 1.7 2 0 0 2 2 2 0 AFG1-like ATPase AAA_25 PF13481.6 CRK28041.1 - 0.066 12.8 1.1 0.19 11.2 0.3 2.2 2 1 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 CRK28041.1 - 0.069 12.9 0.2 1.3 8.7 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 CRK28041.1 - 0.088 12.1 0.1 0.22 10.8 0.0 1.7 2 0 0 2 2 1 0 Zeta toxin AAA_23 PF13476.6 CRK28041.1 - 0.094 13.2 0.4 7 7.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 CRK28041.1 - 0.13 12.6 0.1 0.37 11.1 0.1 1.7 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 CRK28041.1 - 0.14 11.7 0.0 0.34 10.5 0.0 1.6 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SPACA9 PF15120.6 CRK28041.1 - 0.15 11.8 1.0 14 5.4 0.0 2.2 2 0 0 2 2 2 0 Sperm acrosome-associated protein 9 AAA_29 PF13555.6 CRK28041.1 - 0.16 11.7 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Parvo_NS1 PF01057.17 CRK28041.1 - 0.21 10.7 0.0 0.37 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Mis14 PF08641.12 CRK28043.1 - 3.2e-16 59.8 3.3 3.2e-16 59.8 3.3 1.6 2 0 0 2 2 2 1 Kinetochore protein Mis14 like SWIRM-assoc_3 PF16498.5 CRK28043.1 - 0.011 15.9 0.1 1.9 8.8 0.0 2.6 2 0 0 2 2 2 0 SWIRM-associated domain at the C-terminal SOGA PF11365.8 CRK28043.1 - 0.015 16.4 2.6 0.037 15.1 2.6 1.6 1 0 0 1 1 1 0 Protein SOGA Med8 PF10232.9 CRK28043.1 - 0.052 13.1 4.8 0.097 12.2 4.8 1.3 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 Prefoldin PF02996.17 CRK28044.1 - 3.6e-34 117.2 0.4 5.5e-34 116.6 0.4 1.3 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 CRK28044.1 - 0.0045 16.9 0.5 0.071 13.1 0.1 2.5 1 1 0 2 2 2 1 Prefoldin subunit FlaC_arch PF05377.11 CRK28044.1 - 0.021 15.2 0.3 0.7 10.3 0.1 2.6 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Filament PF00038.21 CRK28044.1 - 0.032 13.8 3.9 0.24 11.0 3.9 1.9 1 1 0 1 1 1 0 Intermediate filament protein NACHT_N PF17100.5 CRK28045.1 - 1.6e-49 168.8 0.4 2.7e-49 168.0 0.1 1.6 2 0 0 2 2 2 1 N-terminal domain of NWD NACHT-NTPase Luteo_P1-P2 PF08467.10 CRK28045.1 - 0.051 12.8 0.0 0.094 12.0 0.0 1.4 1 0 0 1 1 1 0 Luteovirus RNA polymerase P1-P2/replicase PglZ PF08665.12 CRK28045.1 - 0.074 13.2 0.1 0.42 10.7 0.1 2.2 2 0 0 2 2 2 0 PglZ domain iPGM_N PF06415.13 CRK28046.1 - 4.6e-75 251.8 0.0 1e-74 250.7 0.0 1.6 2 0 0 2 2 2 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.18 CRK28046.1 - 1.6e-61 207.8 0.0 5e-61 206.2 0.0 1.6 1 1 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 CRK28046.1 - 0.00013 21.4 0.0 0.00021 20.8 0.0 1.4 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 CRK28046.1 - 0.0016 18.1 0.1 0.0025 17.5 0.1 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF1877 PF08974.10 CRK28046.1 - 0.098 12.8 0.0 0.23 11.6 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1877) FRQ PF09421.10 CRK28047.1 - 0 1280.6 38.5 0 1280.2 38.5 1.1 1 0 0 1 1 1 1 Frequency clock protein TBCC PF07986.12 CRK28047.1 - 1.7e-26 92.3 0.0 3e-26 91.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 CRK28047.1 - 1.3e-09 38.5 0.4 8e-09 36.0 0.2 2.4 2 0 0 2 2 2 1 Tubulin-specific chaperone C N-terminal domain Cytochrom_B562 PF07361.11 CRK28047.1 - 0.16 12.6 0.5 22 5.8 0.2 3.2 2 1 1 3 3 3 0 Cytochrome b562 Miga PF10265.9 CRK28047.1 - 1.1 8.2 3.5 2 7.3 3.5 1.4 1 0 0 1 1 1 0 Mitoguardin Amino_oxidase PF01593.24 CRK28049.1 - 1.4e-39 136.7 0.0 4.6e-39 135.0 0.0 1.8 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase LRR_6 PF13516.6 CRK28049.1 - 1.3e-09 37.3 0.2 0.00046 20.0 0.0 4.9 5 0 0 5 5 5 2 Leucine Rich repeat NAD_binding_8 PF13450.6 CRK28049.1 - 9.5e-07 29.0 0.0 3.1e-06 27.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain LRR_4 PF12799.7 CRK28049.1 - 0.017 15.5 0.7 67 4.1 0.0 4.3 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CRK28049.1 - 0.046 14.3 0.0 1.1e+02 4.0 0.0 4.2 3 0 0 3 3 3 0 Leucine Rich Repeat Pyr_redox_2 PF07992.14 CRK28049.1 - 0.098 11.9 0.0 0.41 9.8 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 CRK28049.1 - 0.12 11.7 0.1 0.22 10.8 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ATP-synt_C PF00137.21 CRK28050.1 - 1.9e-10 40.9 12.2 3.9e-10 39.9 12.2 1.5 1 0 0 1 1 1 1 ATP synthase subunit C APOBEC1 PF18769.1 CRK28050.1 - 0.027 14.7 0.0 0.041 14.1 0.0 1.3 1 0 0 1 1 1 0 APOBEC1 PhoD PF09423.10 CRK28052.1 - 1.3e-13 50.8 6.7 4.4e-13 49.0 6.7 1.7 1 1 0 1 1 1 1 PhoD-like phosphatase CCDC84 PF14968.6 CRK28052.1 - 0.033 13.8 0.3 0.037 13.7 0.3 1.0 1 0 0 1 1 1 0 Coiled coil protein 84 Pribosyltran PF00156.27 CRK28054.1 - 0.0037 16.8 0.0 0.0043 16.6 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain SNF2_N PF00176.23 CRK28057.1 - 1.9e-68 230.8 0.1 3.5e-68 229.9 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain eIF-3c_N PF05470.12 CRK28057.1 - 6.6e-22 77.6 0.9 6.6e-22 77.6 0.9 2.8 3 0 0 3 3 3 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Helicase_C PF00271.31 CRK28057.1 - 1.8e-18 66.9 0.0 6.8e-18 65.0 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PCI PF01399.27 CRK28057.1 - 6.1e-12 46.0 0.1 6.1e-12 46.0 0.1 2.8 3 0 0 3 3 3 1 PCI domain ResIII PF04851.15 CRK28057.1 - 5.1e-09 36.4 0.0 1.7e-08 34.6 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit TFIIE_beta PF02186.15 CRK28057.1 - 0.03 14.6 0.0 0.085 13.1 0.0 1.9 1 0 0 1 1 1 0 TFIIE beta subunit core domain FliJ PF02050.16 CRK28057.1 - 1.4 9.1 22.2 0.061 13.5 13.5 3.1 3 0 0 3 3 3 0 Flagellar FliJ protein Ribosomal_S11 PF00411.19 CRK28058.1 - 3.1e-46 156.3 1.2 3.9e-46 156.0 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 BKACE PF05853.12 CRK28058.1 - 0.067 12.5 0.1 0.085 12.2 0.1 1.1 1 0 0 1 1 1 0 beta-keto acid cleavage enzyme CBM_25 PF03423.13 CRK28058.1 - 0.084 13.1 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) Ribosomal_L30_N PF08079.12 CRK28059.1 - 2.3e-05 24.5 2.4 3.8e-05 23.9 2.4 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Fe-S_biosyn PF01521.20 CRK28060.1 - 4.3e-12 46.2 0.0 2.4e-10 40.6 0.0 2.2 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF2207 PF09972.9 CRK28061.1 - 0.018 13.8 0.0 0.049 12.4 0.0 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF3611 PF12263.8 CRK28061.1 - 0.043 13.7 0.2 0.6 10.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3611) ILVD_EDD PF00920.21 CRK28062.1 - 0.011 14.3 0.0 0.014 14.1 0.0 1.0 1 0 0 1 1 1 0 Dehydratase family DUF543 PF04418.12 CRK28063.1 - 2.1e-29 101.3 0.0 2.4e-29 101.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) ABC_cobalt PF09819.9 CRK28063.1 - 0.071 13.3 0.0 0.083 13.0 0.0 1.1 1 0 0 1 1 1 0 ABC-type cobalt transport system, permease component Urb2 PF10441.9 CRK28064.1 - 4.2e-47 160.7 0.6 1.1e-38 133.3 0.1 2.9 1 1 1 2 2 2 2 Urb2/Npa2 family adh_short PF00106.25 CRK28065.1 - 4.5e-27 94.8 0.0 5.8e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK28065.1 - 5.8e-18 65.3 0.0 7.5e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK28065.1 - 2.7e-07 30.7 0.0 4.8e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 CRK28065.1 - 0.048 13.5 0.1 0.16 11.9 0.1 1.8 2 0 0 2 2 2 0 NAD(P)H-binding Shikimate_DH PF01488.20 CRK28065.1 - 0.062 13.4 0.1 0.1 12.7 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.19 CRK28065.1 - 0.065 12.5 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Sas10 PF09368.10 CRK28066.1 - 1.4e-27 96.0 7.5 1.4e-27 96.0 7.5 2.9 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 CRK28066.1 - 1.6e-10 41.5 0.0 8.6e-10 39.1 0.0 2.4 1 0 0 1 1 1 1 Sas10/Utp3/C1D family DUF3723 PF12520.8 CRK28067.1 - 4.1e-06 25.8 0.0 6.6e-06 25.1 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3723) Vhr1 PF04001.13 CRK28072.1 - 0.0087 16.3 0.1 0.012 15.9 0.1 1.3 1 0 0 1 1 1 1 Transcription factor Vhr1 DUF447 PF04289.12 CRK28072.1 - 0.14 11.9 0.0 0.17 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF447) SMBP PF16785.5 CRK28075.1 - 0.052 13.8 0.0 0.059 13.6 0.0 1.0 1 0 0 1 1 1 0 Small metal-binding protein ketoacyl-synt PF00109.26 CRK28079.1 - 6e-26 91.5 2.6 6.6e-26 91.4 2.6 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.23 CRK28079.1 - 1.3e-06 28.0 0.1 1.3e-06 28.0 0.1 1.0 1 0 0 1 1 1 1 Thiolase, N-terminal domain Fungal_trans_2 PF11951.8 CRK28091.1 - 1.5e-29 103.0 6.6 2.6e-19 69.3 0.4 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK28091.1 - 0.0029 17.7 2.4 0.0082 16.3 2.4 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SH3_15 PF18346.1 CRK28091.1 - 0.19 12.0 0.0 0.37 11.1 0.0 1.4 1 0 0 1 1 1 0 Mind bomb SH3 repeat domain adh_short PF00106.25 CRK28092.1 - 2.6e-37 128.2 0.0 3.3e-37 127.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK28092.1 - 9.5e-25 87.5 0.0 1.2e-24 87.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK28092.1 - 2.7e-10 40.5 0.0 4e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 CRK28092.1 - 2.8e-06 27.4 0.0 3.7e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 CRK28092.1 - 1.6e-05 24.5 0.0 2.7e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 CRK28092.1 - 0.0014 18.6 0.0 0.0026 17.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NmrA PF05368.13 CRK28092.1 - 0.0017 17.9 0.1 0.0028 17.2 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family DUF1776 PF08643.10 CRK28092.1 - 0.011 15.1 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) adh_short PF00106.25 CRK28093.1 - 4.1e-22 78.6 0.0 4.7e-21 75.1 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK28093.1 - 4e-11 42.9 0.0 6.4e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 CRK28093.1 - 3.6e-06 26.6 0.0 4.8e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 CRK28093.1 - 1.9e-05 24.6 0.0 2.9e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 CRK28093.1 - 0.0024 17.3 0.0 0.049 13.0 0.0 2.0 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase AdoHcyase_NAD PF00670.21 CRK28093.1 - 0.0094 16.0 1.1 0.088 12.9 0.1 2.1 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Fungal_trans_2 PF11951.8 CRK28094.1 - 7e-07 28.4 0.3 1.1e-06 27.8 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain HEAT PF02985.22 CRK28095.1 - 0.023 14.9 0.0 15 6.2 0.0 3.6 3 0 0 3 3 3 0 HEAT repeat E2_bind PF08825.10 CRK28095.1 - 0.052 13.7 0.0 0.2 11.8 0.0 2.0 1 0 0 1 1 1 0 E2 binding domain DUF3135 PF11333.8 CRK28095.1 - 0.059 13.6 0.6 2.3 8.5 0.0 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3135) TetR_C_28 PF17937.1 CRK28095.1 - 0.066 13.7 0.2 3.9 8.0 0.0 3.2 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Pkinase PF00069.25 CRK28096.1 - 1.7e-67 227.6 0.0 3.1e-67 226.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK28096.1 - 1e-48 165.9 0.0 1.8e-48 165.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 CRK28096.1 - 1.1e-26 93.0 0.0 2.1e-26 92.1 0.0 1.5 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_2 PF07647.17 CRK28096.1 - 3.3e-16 59.2 0.3 1.5e-15 57.0 0.1 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 CRK28096.1 - 2.8e-15 56.5 0.1 5.2e-15 55.6 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 CRK28096.1 - 2.1e-14 53.9 0.1 4.4e-14 52.9 0.1 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Kinase-like PF14531.6 CRK28096.1 - 1.5e-06 27.7 0.0 0.00017 21.0 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CRK28096.1 - 0.0099 14.7 0.0 0.025 13.3 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase SAM_4 PF18017.1 CRK28096.1 - 0.016 15.2 0.0 0.036 14.0 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) NmrA PF05368.13 CRK28097.1 - 4.1e-20 72.3 0.0 5.1e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 CRK28097.1 - 1.5e-16 60.8 0.1 2.2e-16 60.3 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding DapB_N PF01113.20 CRK28097.1 - 4.2e-06 26.9 0.5 8.4e-06 25.9 0.5 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.21 CRK28097.1 - 0.00011 21.8 0.1 0.00085 18.8 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 CRK28097.1 - 0.0057 16.7 0.0 0.0099 15.9 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.24 CRK28097.1 - 0.02 15.3 0.3 0.065 13.7 0.2 2.0 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain FtsX_ECD PF18075.1 CRK28097.1 - 0.11 13.1 0.1 0.25 12.0 0.1 1.6 1 0 0 1 1 1 0 FtsX extracellular domain DJ-1_PfpI PF01965.24 CRK28098.1 - 7.2e-08 32.4 0.0 9.3e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family PDT PF00800.18 CRK28099.1 - 4.9e-53 179.7 0.0 1.5e-52 178.1 0.0 1.7 1 1 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 CRK28099.1 - 5.4e-10 38.9 0.1 1.4e-07 31.1 0.0 2.4 2 0 0 2 2 2 2 ACT domain ACT_4 PF13291.6 CRK28099.1 - 0.006 17.2 0.0 6 7.5 0.0 2.3 2 0 0 2 2 2 2 ACT domain Mhr1 PF12829.7 CRK28100.1 - 4e-35 119.8 0.0 5.1e-35 119.4 0.0 1.1 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination AAA_2 PF07724.14 CRK28101.1 - 5.6e-46 156.8 0.3 1.1e-44 152.5 0.0 3.1 3 1 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 CRK28101.1 - 2e-32 111.2 18.0 4.4e-32 110.1 3.0 4.1 4 0 0 4 4 3 2 AAA lid domain AAA PF00004.29 CRK28101.1 - 1.6e-26 93.3 0.0 6e-14 52.6 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 CRK28101.1 - 9e-24 83.3 2.5 1.5e-23 82.6 0.5 2.6 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 CRK28101.1 - 7.6e-16 58.4 0.0 3.1e-10 40.2 0.0 3.3 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CRK28101.1 - 1.2e-12 48.3 0.0 4.2e-05 23.8 0.0 3.9 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CRK28101.1 - 2.7e-10 40.9 15.0 1.2e-06 29.0 0.1 5.6 4 4 0 5 5 4 2 AAA ATPase domain Sigma54_activat PF00158.26 CRK28101.1 - 5.1e-09 36.1 0.0 3.8e-06 26.7 0.0 2.8 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.6 CRK28101.1 - 1.6e-07 31.4 0.0 0.029 14.4 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.6 CRK28101.1 - 1.9e-06 28.4 1.7 0.097 13.2 0.0 4.4 3 1 1 4 4 4 2 AAA domain AAA_23 PF13476.6 CRK28101.1 - 2.2e-06 28.3 1.0 0.41 11.1 0.0 3.9 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 CRK28101.1 - 2.3e-06 27.5 0.0 0.056 13.2 0.0 3.0 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_7 PF12775.7 CRK28101.1 - 3.6e-06 26.6 0.0 0.016 14.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region Mg_chelatase PF01078.21 CRK28101.1 - 4.3e-06 26.3 0.0 0.26 10.7 0.0 3.6 2 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 CRK28101.1 - 9.9e-06 25.8 0.2 0.26 11.4 0.0 3.6 2 1 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 CRK28101.1 - 1.7e-05 24.9 7.1 0.015 15.2 0.2 4.8 3 2 1 4 4 4 1 ATPase domain predominantly from Archaea Clp_N PF02861.20 CRK28101.1 - 2.5e-05 24.3 4.5 0.00095 19.2 0.4 3.7 3 0 0 3 3 3 1 Clp amino terminal domain, pathogenicity island component AAA_28 PF13521.6 CRK28101.1 - 3.5e-05 24.1 0.0 0.42 10.8 0.0 3.4 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 CRK28101.1 - 5.5e-05 23.5 0.0 0.51 10.8 0.0 2.8 2 0 0 2 2 2 2 RNA helicase RsgA_GTPase PF03193.16 CRK28101.1 - 6.2e-05 23.0 0.0 0.08 12.8 0.0 2.9 2 0 0 2 2 2 1 RsgA GTPase AAA_30 PF13604.6 CRK28101.1 - 7.9e-05 22.5 0.0 0.84 9.3 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.11 CRK28101.1 - 0.0002 21.2 0.0 0.64 9.9 0.0 3.7 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 CRK28101.1 - 0.00023 20.9 0.3 0.58 9.9 0.0 3.6 4 0 0 4 4 3 1 AAA domain ABC_tran PF00005.27 CRK28101.1 - 0.00031 21.3 0.1 0.85 10.1 0.0 3.4 3 0 0 3 3 2 1 ABC transporter AAA_19 PF13245.6 CRK28101.1 - 0.00034 21.0 1.5 0.077 13.3 0.1 3.8 5 1 0 5 5 2 1 AAA domain RuvB_N PF05496.12 CRK28101.1 - 0.0004 20.2 1.7 3.9 7.2 0.9 4.3 3 1 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 CRK28101.1 - 0.00043 20.3 0.0 0.56 10.2 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 CRK28101.1 - 0.0017 17.4 0.0 0.032 13.3 0.0 2.7 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_29 PF13555.6 CRK28101.1 - 0.0029 17.3 0.0 3.1 7.6 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain Zeta_toxin PF06414.12 CRK28101.1 - 0.003 16.9 0.0 0.59 9.4 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin NACHT PF05729.12 CRK28101.1 - 0.0034 17.3 0.0 0.34 10.8 0.0 3.0 3 0 0 3 3 2 1 NACHT domain Rad17 PF03215.15 CRK28101.1 - 0.0039 17.1 0.1 5.5 6.9 0.0 3.4 3 0 0 3 3 3 0 Rad17 P-loop domain ResIII PF04851.15 CRK28101.1 - 0.0056 16.7 0.0 0.99 9.4 0.0 3.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Roc PF08477.13 CRK28101.1 - 0.0063 16.7 0.0 2.2 8.5 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Torsin PF06309.11 CRK28101.1 - 0.01 16.0 0.0 0.055 13.6 0.0 2.1 2 0 0 2 2 2 0 Torsin NTPase_1 PF03266.15 CRK28101.1 - 0.011 15.6 0.0 0.28 11.1 0.0 2.8 2 0 0 2 2 2 0 NTPase SRP54 PF00448.22 CRK28101.1 - 0.017 14.8 0.0 3.8 7.1 0.0 2.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Cytidylate_kin PF02224.18 CRK28101.1 - 0.019 14.7 4.9 9 6.0 1.8 3.9 4 0 0 4 4 3 0 Cytidylate kinase AAA_15 PF13175.6 CRK28101.1 - 0.021 14.5 0.2 20 4.7 0.4 3.4 3 0 0 3 3 3 0 AAA ATPase domain AAA_21 PF13304.6 CRK28101.1 - 0.041 13.7 0.0 14 5.3 0.0 3.3 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF815 PF05673.13 CRK28101.1 - 0.043 13.0 0.0 3 6.9 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF815) KTI12 PF08433.10 CRK28101.1 - 0.043 13.3 2.4 5.9 6.2 0.4 3.4 4 0 0 4 4 3 0 Chromatin associated protein KTI12 AAA_25 PF13481.6 CRK28101.1 - 0.064 12.8 4.0 1.9 8.0 0.0 3.7 4 0 0 4 4 4 0 AAA domain Cob_adeno_trans PF01923.18 CRK28101.1 - 0.074 13.2 6.5 0.21 11.7 2.2 2.9 2 1 0 2 2 2 0 Cobalamin adenosyltransferase Parvo_NS1 PF01057.17 CRK28101.1 - 0.12 11.4 0.0 7.3 5.6 0.0 2.8 3 0 0 3 3 3 0 Parvovirus non-structural protein NS1 ATP_bind_1 PF03029.17 CRK28101.1 - 0.13 12.1 0.0 12 5.6 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 CRK28101.1 - 0.13 12.0 0.0 7.2 6.4 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Cep57_CLD_2 PF14197.6 CRK28101.1 - 0.83 9.8 11.1 4.2 7.5 11.1 2.3 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 Spc7 PF08317.11 CRK28101.1 - 5.9 5.7 12.8 22 3.8 12.8 2.0 1 1 0 1 1 1 0 Spc7 kinetochore protein V_ATPase_I PF01496.19 CRK28101.1 - 6.3 4.6 6.4 0.39 8.6 1.2 1.7 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Peptidase_S46 PF10459.9 CRK28101.1 - 9 4.8 8.8 4.4 5.8 0.1 2.3 2 0 0 2 2 2 0 Peptidase S46 Lyase_aromatic PF00221.19 CRK28102.1 - 2e-160 534.5 11.6 3.2e-148 494.2 8.8 2.0 2 0 0 2 2 2 2 Aromatic amino acid lyase Ribosomal_L9_N PF01281.19 CRK28102.1 - 5.9e-05 22.6 0.0 0.58 9.8 0.0 2.7 2 0 0 2 2 2 2 Ribosomal protein L9, N-terminal domain CRS1_YhbY PF01985.21 CRK28102.1 - 0.048 13.8 0.0 0.99 9.6 0.1 2.5 2 1 0 2 2 2 0 CRS1 / YhbY (CRM) domain Fungal_trans_2 PF11951.8 CRK28104.1 - 1.2e-25 90.2 0.8 2.1e-25 89.4 0.8 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.19 CRK28104.1 - 3.2e-11 43.1 0.0 6.9e-06 25.5 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 CRK28104.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CLIP_SPH_mas PF18398.1 CRK28104.1 - 0.21 12.0 0.2 0.21 12.0 0.2 2.9 4 0 0 4 4 4 0 Clip-domain serine protease homolog masquerade Epimerase PF01370.21 CRK28106.1 - 4.4e-16 59.1 0.0 1.1e-15 57.7 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CRK28106.1 - 1.1e-10 41.5 0.0 2.9e-10 40.1 0.0 1.6 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 CRK28106.1 - 4.5e-10 39.0 0.0 6e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 CRK28106.1 - 4.9e-10 39.6 0.0 7.8e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 CRK28106.1 - 9.6e-07 28.2 0.0 1.6e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 CRK28106.1 - 2.2e-06 27.1 0.0 0.00067 18.9 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein NmrA PF05368.13 CRK28106.1 - 2.2e-05 24.1 0.0 3.9e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.25 CRK28106.1 - 7.2e-05 22.3 0.0 0.00055 19.4 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 CRK28106.1 - 0.018 14.2 0.1 0.064 12.3 0.0 1.8 2 0 0 2 2 2 0 RmlD substrate binding domain KR PF08659.10 CRK28106.1 - 0.13 12.1 0.1 1 9.3 0.1 2.2 1 1 0 1 1 1 0 KR domain EthD PF07110.11 CRK28107.1 - 0.00062 20.9 0.0 0.00082 20.5 0.0 1.2 1 0 0 1 1 1 1 EthD domain UbiA PF01040.18 CRK28108.1 - 2.9e-34 118.5 16.1 4.1e-34 118.0 16.1 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family FAD_binding_4 PF01565.23 CRK28109.1 - 1.8e-48 163.8 12.8 4.8e-25 87.9 2.5 2.9 2 0 0 2 2 2 2 FAD binding domain adh_short PF00106.25 CRK28109.1 - 3.6e-43 147.3 0.0 9.7e-23 80.6 0.0 4.0 4 0 0 4 4 4 3 short chain dehydrogenase AA_permease PF00324.21 CRK28109.1 - 5.5e-29 101.1 6.8 8.1e-29 100.5 6.8 1.2 1 0 0 1 1 1 1 Amino acid permease Epimerase PF01370.21 CRK28109.1 - 3.5e-22 79.0 0.1 2.2e-15 56.8 0.0 4.7 4 0 0 4 4 4 2 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.6 CRK28109.1 - 6.6e-21 74.9 0.0 2.4e-12 46.9 0.0 3.1 3 0 0 3 3 3 2 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 CRK28109.1 - 7.6e-15 55.3 0.5 1.2e-07 31.8 0.0 3.8 4 0 0 4 4 4 3 NAD(P)H-binding NmrA PF05368.13 CRK28109.1 - 2.2e-11 43.8 1.7 0.0024 17.5 0.0 3.4 3 0 0 3 3 3 3 NmrA-like family GDP_Man_Dehyd PF16363.5 CRK28109.1 - 6.1e-10 39.0 0.1 5.6e-09 35.8 0.0 2.6 3 1 0 3 3 3 1 GDP-mannose 4,6 dehydratase KR PF08659.10 CRK28109.1 - 7.5e-10 39.0 2.3 0.007 16.3 0.0 3.9 3 1 0 3 3 3 2 KR domain 3Beta_HSD PF01073.19 CRK28109.1 - 5.7e-09 35.4 0.0 1.1e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 CRK28109.1 - 5.5e-08 32.3 0.0 9e-06 25.0 0.0 3.6 4 0 0 4 4 4 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 CRK28109.1 - 7.3e-05 22.1 0.1 0.0043 16.3 0.0 2.9 3 0 0 3 3 3 1 Male sterility protein DUF4772 PF15997.5 CRK28109.1 - 0.00029 21.4 0.0 0.57 10.8 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4772) RmlD_sub_bind PF04321.17 CRK28109.1 - 0.17 10.9 0.1 0.99 8.4 0.0 2.3 3 0 0 3 3 3 0 RmlD substrate binding domain TcpE PF12648.7 CRK28109.1 - 0.38 11.3 1.7 1 9.9 1.7 1.7 1 0 0 1 1 1 0 TcpE family ADH_zinc_N PF00107.26 CRK28110.1 - 6e-09 36.0 0.0 1.3e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CRK28110.1 - 3.9e-07 29.9 0.0 9.5e-07 28.7 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 CRK28110.1 - 0.013 14.8 0.1 0.019 14.2 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NmrA PF05368.13 CRK28110.1 - 0.16 11.5 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family ADH_N_2 PF16884.5 CRK28110.1 - 0.17 11.8 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase UbiA PF01040.18 CRK28111.1 - 5e-34 117.7 16.4 6.9e-34 117.3 16.4 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family Tim17 PF02466.19 CRK28111.1 - 0.098 13.0 1.7 1.7 9.0 1.0 2.5 2 0 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family ADH_zinc_N PF00107.26 CRK28112.1 - 5.6e-09 36.1 0.0 1.2e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CRK28112.1 - 2.9e-07 30.3 0.0 7e-07 29.1 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 CRK28112.1 - 0.0069 17.4 0.1 0.023 15.8 0.0 1.9 2 1 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 CRK28112.1 - 0.013 14.8 0.1 0.019 14.3 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NmrA PF05368.13 CRK28112.1 - 0.033 13.8 0.0 0.064 12.8 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family PUF PF00806.19 CRK28113.1 - 6.9e-28 94.7 0.0 4e-05 23.1 0.0 5.7 5 0 0 5 5 5 5 Pumilio-family RNA binding repeat RRM_1 PF00076.22 CRK28113.1 - 2.2e-13 49.8 0.0 4.7e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3048_C PF17479.2 CRK28113.1 - 0.0059 17.0 1.9 3.3 8.1 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3048) C-terminal domain CK_II_beta PF01214.18 CRK28113.1 - 0.039 13.8 0.0 12 5.7 0.0 2.3 2 0 0 2 2 2 0 Casein kinase II regulatory subunit DUF3568 PF12092.8 CRK28113.1 - 0.045 13.8 0.6 14 5.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3568) RBM39linker PF15519.6 CRK28113.1 - 0.22 12.6 10.2 8.5 7.5 0.2 4.1 3 0 0 3 3 3 0 linker between RRM2 and RRM3 domains in RBM39 protein Arteri_nsp7a PF16749.5 CRK28113.1 - 1.3 9.2 6.9 31 4.7 0.2 3.2 3 0 0 3 3 3 0 Arterivirus nonstructural protein 7 alpha RTA1 PF04479.13 CRK28115.1 - 1.3e-51 175.2 8.9 1.3e-51 175.2 8.9 1.4 2 0 0 2 2 2 1 RTA1 like protein Caveolin PF01146.17 CRK28115.1 - 7.2 6.6 10.0 0.65 10.0 2.6 2.4 2 0 0 2 2 2 0 Caveolin PHD PF00628.29 CRK28116.1 - 2.8e-13 49.5 19.9 7.4e-08 32.2 9.4 2.4 2 0 0 2 2 2 2 PHD-finger Zf_RING PF16744.5 CRK28116.1 - 0.0083 16.2 9.8 0.072 13.2 0.4 2.5 2 0 0 2 2 2 2 KIAA1045 RING finger C1_1 PF00130.22 CRK28116.1 - 0.17 11.8 12.4 2.1 8.3 1.5 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.6 CRK28116.1 - 0.32 10.6 15.6 0.097 12.2 5.5 3.0 3 0 0 3 3 3 0 PHD-finger zf-HC5HC2H PF13771.6 CRK28116.1 - 0.33 11.3 7.3 0.24 11.7 2.6 2.3 2 0 0 2 2 2 0 PHD-like zinc-binding domain DUF2321 PF10083.9 CRK28116.1 - 0.43 10.2 2.4 1 9.0 2.4 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) PHD_4 PF16866.5 CRK28116.1 - 0.77 9.9 15.7 3.3 7.8 6.3 3.0 3 0 0 3 3 3 0 PHD-finger Prok-RING_1 PF14446.6 CRK28116.1 - 4 7.4 16.7 0.39 10.7 3.2 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-PHD-like PF15446.6 CRK28116.1 - 6.7 6.3 12.3 10 5.7 3.9 2.7 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain PUF PF00806.19 CRK28118.1 - 6.3e-29 98.0 0.0 7.5e-05 22.2 0.0 6.0 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.22 CRK28118.1 - 1.2e-13 50.7 0.0 2.6e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LMBR1 PF04791.16 CRK28119.1 - 0.81 8.5 2.3 0.89 8.4 2.3 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein RTA1 PF04479.13 CRK28120.1 - 1.4e-50 171.8 9.5 1.4e-50 171.8 9.5 1.4 2 0 0 2 2 2 1 RTA1 like protein Peptidase_M24 PF00557.24 CRK28121.1 - 4.8e-16 59.1 0.0 2.8e-07 30.5 0.0 2.7 2 0 0 2 2 2 2 Metallopeptidase family M24 PHD PF00628.29 CRK28121.1 - 1.2e-12 47.5 19.3 2.5e-07 30.5 9.6 2.5 2 0 0 2 2 2 2 PHD-finger GGACT PF06094.12 CRK28121.1 - 7.2e-05 23.4 0.0 0.00017 22.2 0.0 1.6 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 CRK28121.1 - 0.0012 19.2 0.0 0.0031 17.9 0.0 1.7 1 0 0 1 1 1 1 AIG2-like family DUF3113 PF11310.8 CRK28121.1 - 0.057 13.4 0.3 16 5.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3113) MecA PF05389.12 CRK28121.1 - 0.059 13.0 5.6 0.13 11.8 0.2 2.8 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) Zf_RING PF16744.5 CRK28121.1 - 0.084 13.0 10.2 0.22 11.6 0.5 2.6 2 0 0 2 2 2 0 KIAA1045 RING finger PHD_2 PF13831.6 CRK28121.1 - 0.36 10.4 12.8 0.41 10.2 6.0 2.8 2 0 0 2 2 2 0 PHD-finger DUF3982 PF13138.6 CRK28121.1 - 0.69 9.8 5.4 15 5.5 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3982) C1_1 PF00130.22 CRK28121.1 - 1.3 8.9 12.5 6.4 6.8 1.6 2.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) IR1-M PF12185.8 CRK28121.1 - 1.4 8.9 4.4 21 5.1 0.7 3.0 2 0 0 2 2 2 0 Nup358/RanBP2 E3 ligase domain zf-HC5HC2H PF13771.6 CRK28121.1 - 2.4 8.5 7.9 0.47 10.7 2.2 2.4 2 0 0 2 2 2 0 PHD-like zinc-binding domain PHD_4 PF16866.5 CRK28121.1 - 5 7.3 15.4 9.2 6.4 6.5 2.9 2 0 0 2 2 2 0 PHD-finger AP3D1 PF06375.11 CRK28121.1 - 5.2 7.3 21.6 2.3 8.4 3.8 3.3 3 0 0 3 3 3 0 AP-3 complex subunit delta-1 Cas_Cmr5 PF09701.10 CRK28121.1 - 9.4 6.6 6.9 47 4.3 0.8 2.8 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cmr5) Asp PF00026.23 CRK28122.1 - 6.1e-144 479.2 6.5 2.6e-72 243.9 0.5 3.2 3 0 0 3 3 3 3 Eukaryotic aspartyl protease SNF5 PF04855.12 CRK28122.1 - 1.2e-64 218.4 0.1 5.7e-64 216.2 0.1 2.0 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 Pep3_Vps18 PF05131.14 CRK28122.1 - 1.8e-44 151.2 0.0 3.4e-44 150.2 0.0 1.5 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family TAXi_N PF14543.6 CRK28122.1 - 6.6e-24 85.1 11.0 2.2e-11 44.3 0.8 4.5 3 1 0 3 3 3 3 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 CRK28122.1 - 2.2e-10 41.1 0.5 1.4 9.7 0.1 7.1 6 1 0 6 6 6 2 Aspartyl protease Clathrin PF00637.20 CRK28122.1 - 3.8e-06 26.8 1.8 0.0003 20.7 0.0 2.6 2 0 0 2 2 2 1 Region in Clathrin and VPS zf-C3HC4_2 PF13923.6 CRK28122.1 - 0.001 18.9 0.6 0.0021 17.9 0.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CRK28122.1 - 0.0016 18.4 0.4 0.0035 17.3 0.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain QueF_N PF14819.6 CRK28122.1 - 0.0041 17.4 0.4 5.5 7.3 0.1 2.6 2 0 0 2 2 2 2 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term DUF2175 PF09943.9 CRK28122.1 - 0.0055 17.0 4.6 0.0067 16.7 0.1 2.8 3 0 0 3 3 3 1 Uncharacterized protein conserved in archaea (DUF2175) Zn_ribbon_17 PF17120.5 CRK28122.1 - 0.0056 16.3 0.1 0.011 15.4 0.1 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_2 PF13639.6 CRK28122.1 - 0.012 15.9 0.5 0.027 14.8 0.5 1.6 1 0 0 1 1 1 0 Ring finger domain zf-RING_UBOX PF13445.6 CRK28122.1 - 0.038 14.0 0.6 0.089 12.8 0.6 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3H2C3 PF17122.5 CRK28122.1 - 0.068 13.2 2.5 0.17 12.0 2.5 1.6 1 0 0 1 1 1 0 Zinc-finger Vps39_2 PF10367.9 CRK28122.1 - 0.085 13.3 0.0 0.2 12.1 0.0 1.7 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 zf-RING_11 PF17123.5 CRK28122.1 - 4.5 7.1 11.5 0.16 11.8 4.4 2.4 2 0 0 2 2 2 0 RING-like zinc finger ATP-synt_C PF00137.21 CRK28123.1 - 4.9e-29 100.4 26.3 2.2e-20 72.7 12.8 2.2 2 0 0 2 2 2 2 ATP synthase subunit C TCR_zetazeta PF11628.8 CRK28123.1 - 0.32 10.7 2.2 10 5.9 0.1 2.5 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 zeta chain ATP-synt_C PF00137.21 CRK28124.1 - 5.2e-29 100.4 26.3 2.2e-20 72.7 12.8 2.1 2 0 0 2 2 2 2 ATP synthase subunit C TCR_zetazeta PF11628.8 CRK28124.1 - 0.32 10.7 2.2 10 5.9 0.1 2.5 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 zeta chain Methyltransf_23 PF13489.6 CRK28125.1 - 3.1e-15 56.4 0.0 5.4e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK28125.1 - 1e-09 39.0 0.0 3.1e-09 37.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK28125.1 - 8.7e-09 36.0 0.0 2.6e-08 34.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK28125.1 - 1.3e-07 31.5 0.0 6.8e-07 29.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CRK28125.1 - 4.6e-07 30.4 0.0 1.3e-06 29.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CRK28125.1 - 0.00081 18.8 0.0 0.004 16.5 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 CRK28125.1 - 0.0061 16.0 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_2 PF00891.18 CRK28125.1 - 0.013 14.8 0.0 0.035 13.4 0.0 1.7 2 0 0 2 2 2 0 O-methyltransferase domain CMAS PF02353.20 CRK28125.1 - 0.18 11.1 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PPP4R2 PF09184.11 CRK28125.1 - 0.39 10.3 1.3 0.53 9.8 1.3 1.1 1 0 0 1 1 1 0 PPP4R2 GDP_Man_Dehyd PF16363.5 CRK28126.1 - 1.8e-69 234.7 0.0 2.1e-69 234.5 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CRK28126.1 - 2e-56 191.2 0.0 2.5e-56 190.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 CRK28126.1 - 3.2e-24 85.6 0.0 3.6e-23 82.1 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 CRK28126.1 - 8e-20 71.0 0.0 1e-19 70.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 CRK28126.1 - 2.8e-18 66.0 0.1 3.5e-17 62.4 0.1 2.0 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 CRK28126.1 - 1.7e-17 63.4 0.0 2.1e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 CRK28126.1 - 2.9e-08 33.8 0.0 7.1e-08 32.6 0.0 1.5 2 0 0 2 2 2 1 NAD(P)H-binding adh_short PF00106.25 CRK28126.1 - 0.047 13.1 0.0 1.5 8.2 0.1 2.4 2 0 0 2 2 2 0 short chain dehydrogenase TPT PF03151.16 CRK28127.1 - 3.5e-09 36.4 19.1 4.5e-09 36.1 19.1 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UPF0139 PF03669.13 CRK28127.1 - 0.055 13.3 0.1 0.055 13.3 0.1 2.2 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0139) Tuberculin PF12198.8 CRK28127.1 - 0.16 12.0 0.1 0.37 10.9 0.1 1.6 1 0 0 1 1 1 0 Theoretical tuberculin protein DUF2613 PF11021.8 CRK28127.1 - 0.35 11.0 0.1 0.35 11.0 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2613) Brix PF04427.18 CRK28128.1 - 6.2e-25 88.4 0.3 1e-24 87.7 0.3 1.3 1 0 0 1 1 1 1 Brix domain RRN3 PF05327.11 CRK28128.1 - 1.6 7.2 9.4 2 6.8 9.4 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 BUD22 PF09073.10 CRK28128.1 - 2 7.7 29.5 2.9 7.1 29.5 1.1 1 0 0 1 1 1 0 BUD22 Sporozoite_P67 PF05642.11 CRK28128.1 - 8.5 4.3 8.7 13 3.7 8.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen HGTP_anticodon PF03129.20 CRK28129.1 - 9.4e-20 70.6 0.1 9.4e-20 70.6 0.1 2.7 3 0 0 3 3 3 1 Anticodon binding domain tRNA-synt_2b PF00587.25 CRK28129.1 - 1e-08 35.4 0.0 4.5e-07 30.0 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Methyltransf_23 PF13489.6 CRK28130.1 - 2.4e-15 56.7 0.0 4.7e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK28130.1 - 2e-09 38.0 0.0 1.3e-08 35.4 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK28130.1 - 4e-08 33.9 0.0 1.2e-07 32.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK28130.1 - 5.3e-07 29.5 0.0 2.3e-06 27.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CRK28130.1 - 6.1e-07 30.0 0.0 3e-06 27.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.18 CRK28130.1 - 0.0099 15.2 0.0 0.028 13.7 0.0 1.7 2 0 0 2 2 2 1 O-methyltransferase domain Ubie_methyltran PF01209.18 CRK28130.1 - 0.01 15.2 0.0 0.043 13.2 0.0 1.9 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 CRK28130.1 - 0.019 14.5 0.0 0.044 13.3 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase CHASE7 PF17151.4 CRK28130.1 - 0.18 11.4 0.1 0.3 10.7 0.1 1.3 1 0 0 1 1 1 0 Periplasmic sensor domain TPT PF03151.16 CRK28132.1 - 2e-09 37.2 18.3 2.6e-09 36.8 18.3 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UPF0139 PF03669.13 CRK28132.1 - 0.038 13.8 0.1 0.038 13.8 0.1 2.3 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0139) Tuberculin PF12198.8 CRK28132.1 - 0.12 12.5 0.1 0.38 10.9 0.1 1.9 1 0 0 1 1 1 0 Theoretical tuberculin protein DUF2613 PF11021.8 CRK28132.1 - 0.7 10.0 0.1 0.7 10.0 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2613) Brix PF04427.18 CRK28133.1 - 7.1e-25 88.2 0.3 1.2e-24 87.5 0.3 1.3 1 0 0 1 1 1 1 Brix domain BUD22 PF09073.10 CRK28133.1 - 0.39 10.0 26.5 0.55 9.5 26.5 1.1 1 0 0 1 1 1 0 BUD22 HGTP_anticodon PF03129.20 CRK28134.1 - 5.6e-20 71.3 0.0 5.6e-20 71.3 0.0 2.7 3 0 0 3 3 3 1 Anticodon binding domain tRNA-synt_2b PF00587.25 CRK28134.1 - 1.3e-08 35.0 0.0 5.1e-07 29.8 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Pkinase PF00069.25 CRK28135.1 - 2.6e-50 171.2 0.0 3.1e-50 171.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK28135.1 - 1.8e-33 115.9 0.0 2.1e-33 115.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CRK28135.1 - 6.2e-08 32.3 0.0 7.5e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CRK28135.1 - 3.1e-07 29.5 0.0 4.5e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 CRK28135.1 - 0.0037 16.4 0.2 0.0067 15.5 0.0 1.4 2 0 0 2 2 2 1 Seadornavirus VP7 APH PF01636.23 CRK28135.1 - 0.0048 16.8 0.0 0.0071 16.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family KIND PF16474.5 CRK28135.1 - 0.012 15.5 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 Kinase non-catalytic C-lobe domain Haspin_kinase PF12330.8 CRK28135.1 - 0.017 14.0 0.1 0.023 13.6 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 CRK28135.1 - 0.057 12.8 0.1 0.085 12.2 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 CRK28136.1 - 3.4e-70 236.4 4.1 2.9e-67 226.8 1.2 3.2 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CRK28136.1 - 1.6e-54 184.9 1.7 1.6e-51 175.1 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase PBD PF00786.28 CRK28136.1 - 4.9e-36 122.9 0.1 1.6e-23 82.8 0.0 3.1 2 0 0 2 2 2 2 P21-Rho-binding domain Zn_clus PF00172.18 CRK28136.1 - 1.3e-08 34.8 10.4 2.3e-08 34.0 10.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Kinase-like PF14531.6 CRK28136.1 - 6.3e-07 29.0 0.0 1.7e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Kinase-like PH_11 PF15413.6 CRK28136.1 - 6e-06 26.6 0.0 2.5e-05 24.6 0.0 2.2 1 0 0 1 1 1 1 Pleckstrin homology domain Pkinase_fungal PF17667.1 CRK28136.1 - 1e-05 24.5 0.0 1e-05 24.5 0.0 2.5 3 0 0 3 3 3 1 Fungal protein kinase PH PF00169.29 CRK28136.1 - 0.01 16.3 0.0 0.022 15.3 0.0 1.6 1 0 0 1 1 1 0 PH domain Haspin_kinase PF12330.8 CRK28136.1 - 0.027 13.4 0.1 0.055 12.4 0.1 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 CRK28136.1 - 0.06 12.4 0.0 0.099 11.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 PIG-X PF08320.12 CRK28137.1 - 8.1e-67 225.2 0.0 1.1e-66 224.7 0.0 1.2 1 0 0 1 1 1 1 PIG-X / PBN1 2OG-FeII_Oxy_3 PF13640.6 CRK28137.1 - 8.4e-06 26.6 0.3 3e-05 24.8 0.3 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fungal_trans PF04082.18 CRK28141.1 - 1e-14 54.3 0.2 2.5e-14 53.0 0.2 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK28141.1 - 2.4e-10 40.4 11.8 3.9e-10 39.7 11.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3669 PF12417.8 CRK28142.1 - 4.6e-24 84.4 0.1 6e-23 80.8 0.1 2.3 2 0 0 2 2 2 1 Zinc finger protein PBP PF01161.20 CRK28142.1 - 3.8e-12 46.7 0.0 7e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein PBP-Tp47_a PF14889.6 CRK28142.1 - 0.023 14.3 0.0 0.042 13.5 0.0 1.3 1 0 0 1 1 1 0 Penicillin-binding protein Tp47 domain a AAA_lid_2 PF17863.1 CRK28142.1 - 0.31 10.9 2.2 0.82 9.6 2.2 1.7 1 0 0 1 1 1 0 AAA lid domain PrpF PF04303.13 CRK28143.1 - 1.1e-77 261.6 0.0 2.2e-77 260.5 0.0 1.4 1 0 0 1 1 1 1 PrpF protein DUF3605 PF12239.8 CRK28143.1 - 5.7e-56 189.1 0.0 9.6e-56 188.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) EBP PF05241.12 CRK28143.1 - 1.4e-49 168.0 5.3 2.7e-49 167.0 5.3 1.4 1 0 0 1 1 1 1 Emopamil binding protein TPR_1 PF00515.28 CRK28143.1 - 1.1e-31 107.3 12.8 1.1e-05 25.0 0.0 8.8 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_2 PF07719.17 CRK28143.1 - 3.7e-31 104.7 30.4 1.2e-05 25.0 0.0 11.0 11 0 0 11 11 11 7 Tetratricopeptide repeat ANAPC3 PF12895.7 CRK28143.1 - 9.7e-25 86.6 17.9 1e-18 67.3 0.0 5.8 4 1 2 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 CRK28143.1 - 5.2e-18 63.7 17.0 0.015 15.4 0.1 10.6 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_12 PF13424.6 CRK28143.1 - 3.6e-15 56.0 24.8 0.14 12.5 0.1 9.2 7 2 0 8 8 7 5 Tetratricopeptide repeat TPR_7 PF13176.6 CRK28143.1 - 5.7e-15 54.2 3.8 0.25 11.5 0.0 7.3 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 CRK28143.1 - 9.5e-15 54.9 17.9 0.00018 21.9 0.0 6.6 6 1 1 7 7 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 CRK28143.1 - 2.1e-14 52.9 9.2 5.9e-06 25.9 1.9 7.7 4 2 4 8 8 8 3 TPR repeat TPR_16 PF13432.6 CRK28143.1 - 1.1e-13 51.5 25.0 2.4e-06 28.1 0.3 7.7 7 1 1 8 8 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 CRK28143.1 - 1.8e-13 50.1 18.4 0.12 13.2 0.1 9.6 5 3 4 9 9 9 3 Tetratricopeptide repeat TPR_17 PF13431.6 CRK28143.1 - 5.7e-12 45.1 7.5 0.057 13.8 0.2 8.9 9 0 0 9 9 9 2 Tetratricopeptide repeat CENP-T_C PF15511.6 CRK28143.1 - 7.9e-07 29.2 0.0 2e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TPR_9 PF13371.6 CRK28143.1 - 5.8e-05 23.2 8.1 0.76 10.0 1.5 5.4 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 CRK28143.1 - 0.00023 21.6 17.2 2.4 9.0 0.0 8.9 11 0 0 11 11 8 1 Tetratricopeptide repeat Histone PF00125.24 CRK28143.1 - 0.0028 18.0 0.8 0.0064 16.8 0.1 2.0 2 0 0 2 2 1 1 Core histone H2A/H2B/H3/H4 TPR_15 PF13429.6 CRK28143.1 - 0.003 16.8 10.0 0.52 9.5 0.7 3.8 3 2 0 3 3 3 2 Tetratricopeptide repeat TAF PF02969.17 CRK28143.1 - 0.007 16.5 0.0 0.017 15.3 0.0 1.6 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 CRK28143.1 - 0.0072 16.6 0.2 0.091 13.1 0.0 2.8 3 0 0 3 3 3 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 CRK28143.1 - 0.027 14.9 0.0 0.071 13.5 0.0 1.7 1 0 0 1 1 1 0 CENP-S protein DUF2225 PF09986.9 CRK28143.1 - 0.096 12.4 4.5 6.5 6.4 0.2 3.6 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_4 PF07721.14 CRK28143.1 - 0.11 13.1 0.6 12 6.9 1.0 4.1 5 0 0 5 5 2 0 Tetratricopeptide repeat TpcC PF12642.7 CRK28143.1 - 0.18 11.6 0.1 0.57 9.9 0.0 1.8 2 0 0 2 2 2 0 Conjugative transposon protein TcpC TPR_20 PF14561.6 CRK28143.1 - 1.1 9.7 5.2 4.5 7.7 2.5 2.9 2 1 1 3 3 2 0 Tetratricopeptide repeat Sedlin_N PF04628.13 CRK28144.1 - 6.1e-47 159.0 0.0 7e-47 158.8 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 CRK28144.1 - 4.2e-05 23.5 0.0 0.0028 17.6 0.0 2.1 2 0 0 2 2 2 2 Sybindin-like family DUF4110 PF13422.6 CRK28144.1 - 0.086 12.9 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4110) L31 PF09784.9 CRK28145.1 - 6.5e-46 155.0 0.4 7.3e-46 154.8 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 Histone_HNS PF00816.21 CRK28145.1 - 0.059 14.2 1.0 0.069 14.0 1.0 1.1 1 0 0 1 1 1 0 H-NS histone family RRM_1 PF00076.22 CRK28146.1 - 2.2e-16 59.4 0.0 3.3e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup88 PF10168.9 CRK28147.1 - 0.0061 14.4 9.0 0.025 12.4 0.0 2.7 2 1 0 2 2 2 1 Nuclear pore component DUF948 PF06103.11 CRK28147.1 - 0.44 10.8 2.3 3.7 7.9 0.2 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) CBFD_NFYB_HMF PF00808.23 CRK28148.1 - 2.2e-12 47.0 2.2 3.6e-12 46.4 2.2 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIIA PF03153.13 CRK28148.1 - 0.0012 18.9 35.1 0.0018 18.3 35.1 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Histone PF00125.24 CRK28148.1 - 0.061 13.7 0.0 0.061 13.7 0.0 2.7 3 0 0 3 3 3 0 Core histone H2A/H2B/H3/H4 PI3_PI4_kinase PF00454.27 CRK28150.1 - 4.9e-57 193.6 0.0 5.4e-34 118.1 0.0 2.5 2 1 0 2 2 2 2 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.8 CRK28150.1 - 3.2e-18 65.4 0.0 7.9e-18 64.2 0.0 1.7 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 CBFD_NFYB_HMF PF00808.23 CRK28150.1 - 8.5e-07 29.2 1.2 8.5e-07 29.2 1.2 2.0 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF4135 PF13575.6 CRK28150.1 - 3.9e-06 26.5 0.0 0.022 14.1 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4135) CXCR4_N PF12109.8 CRK28150.1 - 2.1e-05 24.6 0.9 0.21 11.8 0.1 2.6 2 0 0 2 2 2 2 CXCR4 Chemokine receptor N terminal Say1_Mug180 PF10340.9 CRK28151.1 - 5.3e-21 74.9 0.0 3.5e-14 52.4 0.0 2.2 2 0 0 2 2 2 2 Steryl acetyl hydrolase Abhydrolase_3 PF07859.13 CRK28151.1 - 1.1e-19 71.1 0.1 1.7e-19 70.6 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 CRK28151.1 - 0.023 13.6 0.1 2.3 7.0 0.0 2.1 2 0 0 2 2 2 0 Carboxylesterase family DUF2834 PF11196.8 CRK28153.1 - 0.0011 19.3 7.7 0.069 13.5 0.4 3.2 3 1 0 3 3 3 2 Protein of unknown function (DUF2834) Tim17 PF02466.19 CRK28154.1 - 1e-24 87.0 4.9 1.5e-24 86.5 4.9 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Cm_res_leader PF08077.11 CRK28154.1 - 0.57 10.4 7.1 2.4 8.5 0.2 4.3 4 0 0 4 4 4 0 Chloramphenicol resistance gene leader peptide CoaE PF01121.20 CRK28155.1 - 5.5e-38 130.4 0.0 1.2e-37 129.3 0.0 1.5 1 1 0 1 1 1 1 Dephospho-CoA kinase UnbV_ASPIC PF07593.12 CRK28155.1 - 0.031 14.3 0.3 0.27 11.2 0.0 2.5 3 0 0 3 3 3 0 ASPIC and UnbV p450 PF00067.22 CRK28156.1 - 1.8e-51 175.3 0.0 1.7e-41 142.5 0.0 2.0 1 1 0 2 2 2 2 Cytochrome P450 HK PF02110.15 CRK28157.1 - 3.3e-40 138.0 3.2 4.2e-40 137.7 3.2 1.0 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family DUF2530 PF10745.9 CRK28157.1 - 0.011 16.0 4.2 0.52 10.6 2.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) Carb_kinase PF01256.17 CRK28157.1 - 0.013 15.0 3.1 0.016 14.7 2.0 1.6 1 1 1 2 2 2 0 Carbohydrate kinase Isochorismatase PF00857.20 CRK28158.1 - 1.6e-31 109.9 0.3 2e-31 109.5 0.3 1.2 1 0 0 1 1 1 1 Isochorismatase family Sars6 PF12133.8 CRK28158.1 - 0.036 14.0 0.1 0.077 12.9 0.1 1.5 1 0 0 1 1 1 0 Open reading frame 6 from SARS coronavirus SIS_2 PF13580.6 CRK28158.1 - 0.073 13.1 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 SIS domain TIM PF00121.18 CRK28159.1 - 6.5e-88 294.2 0.3 7.5e-88 294.0 0.3 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase L51_S25_CI-B8 PF05047.16 CRK28160.1 - 2.4e-11 43.3 0.0 4.5e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain U1snRNP70_N PF12220.8 CRK28161.1 - 9.6e-26 90.3 3.6 9.6e-26 90.3 3.6 2.0 2 0 0 2 2 2 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 CRK28161.1 - 5.8e-17 61.3 0.1 8.6e-16 57.5 0.1 2.2 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CRK28161.1 - 5.4e-05 23.2 0.0 9.3e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif Cullin PF00888.22 CRK28162.1 - 3.5e-156 521.4 0.0 7.5e-155 517.0 0.0 2.4 1 1 0 1 1 1 1 Cullin family PI3_PI4_kinase PF00454.27 CRK28162.1 - 1e-46 159.8 0.0 3.1e-46 158.2 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.8 CRK28162.1 - 5.7e-44 149.9 4.8 1.1e-43 148.9 0.1 3.9 3 0 0 3 3 3 1 Telomere-length maintenance and DNA damage repair Cullin_Nedd8 PF10557.9 CRK28162.1 - 7.4e-22 77.2 0.1 2e-21 75.8 0.1 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain FAT PF02259.23 CRK28162.1 - 3.5e-10 39.6 5.8 4.1e-10 39.4 4.1 2.0 2 0 0 2 2 2 1 FAT domain FATC PF02260.20 CRK28162.1 - 6e-07 29.2 0.1 1.5e-06 27.9 0.1 1.7 1 0 0 1 1 1 1 FATC domain SPACA9 PF15120.6 CRK28162.1 - 0.066 13.0 0.1 2.5 7.9 0.0 2.9 2 0 0 2 2 2 0 Sperm acrosome-associated protein 9 U3snoRNP10 PF12397.8 CRK28162.1 - 3.5 8.0 5.1 65 3.9 0.1 4.3 4 0 0 4 4 4 0 U3 small nucleolar RNA-associated protein 10 DNApol_Exo PF18136.1 CRK28163.1 - 1.3e-103 346.0 0.0 4.1e-103 344.4 0.0 1.8 2 0 0 2 2 2 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 CRK28163.1 - 1.9e-56 191.8 0.0 3.2e-56 191.0 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family A Hepatitis_core PF00906.20 CRK28164.1 - 5.1 6.6 5.7 0.45 10.0 1.3 1.5 2 0 0 2 2 2 0 Hepatitis core antigen Zn_clus PF00172.18 CRK28165.1 - 4.6e-09 36.3 6.7 9.6e-09 35.2 6.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1640 PF07798.11 CRK28172.1 - 1.1e-45 155.8 4.1 1.9e-45 155.0 4.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DUF3854 PF12965.7 CRK28172.1 - 0.015 15.3 0.2 0.65 10.0 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3854) EphA2_TM PF14575.6 CRK28174.1 - 0.049 14.5 0.0 0.08 13.8 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SRTM1 PF15872.5 CRK28174.1 - 0.16 12.1 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 Serine-rich and transmembrane domain-containing protein 1 LapA_dom PF06305.11 CRK28174.1 - 0.44 10.4 1.7 0.84 9.5 1.7 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain GATA PF00320.27 CRK28177.1 - 0.05 13.2 0.1 0.05 13.2 0.1 1.6 2 0 0 2 2 2 0 GATA zinc finger Cnd3 PF12719.7 CRK28178.1 - 0.016 14.4 0.0 0.029 13.6 0.0 1.4 1 0 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain CNH PF00780.22 CRK28180.1 - 0.21 11.2 0.0 1.8 8.1 0.0 2.1 2 0 0 2 2 2 0 CNH domain Proteasome_A_N PF10584.9 CRK28180.1 - 4.5 7.0 5.2 42 4.0 0.0 3.6 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature MoaC PF01967.21 CRK28182.1 - 1.3e-54 183.9 1.0 2.2e-54 183.2 1.0 1.4 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.13 CRK28182.1 - 2.2e-36 124.6 0.0 1.9e-35 121.5 0.0 2.2 2 0 0 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 CRK28182.1 - 2.2e-25 90.0 0.0 4.2e-25 89.0 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 CRK28182.1 - 2.3e-05 24.7 0.0 4.5e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 CRK28182.1 - 0.17 12.0 0.0 0.5 10.5 0.0 1.8 1 0 0 1 1 1 0 4Fe-4S single cluster domain FYVE PF01363.21 CRK28184.1 - 2.8e-11 43.4 4.2 5e-11 42.6 4.2 1.4 1 0 0 1 1 1 1 FYVE zinc finger zf-AN1 PF01428.16 CRK28184.1 - 2.1 8.6 9.2 0.079 13.1 3.3 1.7 2 0 0 2 2 2 0 AN1-like Zinc finger ELO PF01151.18 CRK28185.1 - 1.7e-80 270.1 8.8 2.1e-80 269.9 8.8 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family DUF423 PF04241.15 CRK28185.1 - 1.2 9.4 7.4 2.1 8.6 0.3 2.9 1 1 0 2 2 2 0 Protein of unknown function (DUF423) GMC_oxred_N PF00732.19 CRK28186.1 - 4.1e-40 138.0 1.6 8.6e-40 136.9 1.6 1.6 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CRK28186.1 - 5.1e-31 108.1 0.2 4e-30 105.2 0.0 2.3 2 0 0 2 2 2 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 CRK28186.1 - 1.4e-06 27.8 0.5 1.8e-05 24.1 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CRK28186.1 - 9.7e-06 24.9 2.9 7.5e-05 22.0 0.8 2.2 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 CRK28186.1 - 2.3e-05 24.2 3.9 0.0026 17.4 0.4 2.6 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 CRK28186.1 - 4.1e-05 23.0 0.1 7e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 CRK28186.1 - 4.8e-05 23.5 0.1 0.00015 21.9 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CRK28186.1 - 0.02 14.1 0.1 0.042 13.1 0.1 1.4 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 CRK28186.1 - 0.027 13.2 0.2 0.027 13.2 0.2 1.9 2 1 1 3 3 3 0 HI0933-like protein UDPG_MGDP_dh_N PF03721.14 CRK28186.1 - 0.051 13.1 0.7 0.082 12.5 0.7 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_oxidored PF12831.7 CRK28186.1 - 0.052 12.9 0.4 0.08 12.3 0.4 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 CRK28186.1 - 0.074 12.9 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 CRK28186.1 - 0.076 12.1 0.2 0.13 11.3 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.27 CRK28186.1 - 0.092 13.3 0.1 0.26 11.9 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 CRK28186.1 - 0.097 12.3 0.1 0.17 11.5 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 CRK28186.1 - 0.11 11.8 0.0 5.2 6.2 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF3301 PF11743.8 CRK28189.1 - 0.16 11.6 1.1 0.3 10.8 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3301) DUF5320 PF17253.2 CRK28189.1 - 0.29 12.2 10.1 0.54 11.3 3.1 2.4 3 0 0 3 3 3 0 Family of unknown function (DUF5320) VASt PF16016.5 CRK28190.1 - 7.1e-34 117.4 0.2 1.8e-33 116.1 0.2 1.7 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain BAR_3 PF16746.5 CRK28190.1 - 1.3e-12 48.0 0.0 2.2e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 CRK28190.1 - 1.7e-05 25.2 0.0 4.2e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 PH domain GRAM PF02893.20 CRK28190.1 - 0.034 14.0 0.0 0.068 13.1 0.0 1.4 1 0 0 1 1 1 0 GRAM domain SCP-1 PF05483.12 CRK28190.1 - 0.3 9.1 0.0 0.44 8.5 0.0 1.1 1 0 0 1 1 1 0 Synaptonemal complex protein 1 (SCP-1) DUF3074 PF11274.8 CRK28191.1 - 5.9e-59 199.2 0.3 5.3e-58 196.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3074) START PF01852.19 CRK28191.1 - 0.027 13.9 0.0 0.21 11.0 0.0 2.2 2 1 0 2 2 2 0 START domain DUF1796 PF08795.10 CRK28191.1 - 0.5 10.3 5.4 1.9 8.4 0.0 2.8 2 1 0 2 2 2 0 Putative papain-like cysteine peptidase (DUF1796) FapA PF03961.13 CRK28191.1 - 2.4 6.7 10.2 3.6 6.1 10.2 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A PAS_3 PF08447.12 CRK28211.1 - 6.9e-12 45.5 0.0 1.1e-11 44.9 0.0 1.3 1 1 0 1 1 1 1 PAS fold PAS PF00989.25 CRK28211.1 - 1.3e-08 34.8 0.0 1.5e-08 34.6 0.0 1.0 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 CRK28211.1 - 5.4e-05 23.4 0.0 6.7e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 PAS domain PAS_11 PF14598.6 CRK28211.1 - 0.00011 22.3 0.0 0.00015 21.8 0.0 1.1 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 CRK28211.1 - 0.00064 19.9 0.0 0.00073 19.8 0.0 1.1 1 0 0 1 1 1 1 PAS fold SRA1 PF07304.11 CRK28217.1 - 3.9e-05 23.5 0.2 3.9e-05 23.5 0.2 2.9 1 1 2 3 3 3 1 Steroid receptor RNA activator (SRA1) Prp18 PF02840.15 CRK28217.1 - 0.00077 19.5 0.1 0.00097 19.2 0.1 1.1 1 0 0 1 1 1 1 Prp18 domain B12D PF06522.11 CRK28219.1 - 7.6e-06 25.6 0.0 1e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit COX6B PF02297.17 CRK28220.1 - 1.7e-17 63.4 4.9 1.9e-17 63.3 4.9 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb APOBEC_C PF05240.14 CRK28220.1 - 0.071 13.1 2.9 0.088 12.8 2.5 1.4 1 1 0 1 1 1 0 APOBEC-like C-terminal domain ketoacyl-synt PF00109.26 CRK28220.1 - 0.088 12.4 0.0 0.097 12.2 0.0 1.1 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain CX9C PF16860.5 CRK28220.1 - 0.11 12.5 3.0 0.17 11.9 3.0 1.2 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Sde2_N_Ubi PF13019.6 CRK28221.1 - 1.9e-70 236.0 0.3 3.2e-70 235.2 0.3 1.4 1 0 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain Peripla_BP_6 PF13458.6 CRK28221.1 - 0.093 12.4 0.1 0.15 11.7 0.1 1.2 1 0 0 1 1 1 0 Periplasmic binding protein S10_plectin PF03501.15 CRK28222.1 - 9.2e-23 80.1 0.1 4.7e-19 68.2 0.0 2.1 1 1 1 2 2 2 2 Plectin/S10 domain ADH_N PF08240.12 CRK28223.1 - 2.5e-34 117.4 0.6 5.1e-34 116.4 0.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CRK28223.1 - 1.4e-15 57.4 0.0 2.3e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 CRK28223.1 - 2.1e-10 40.5 0.0 3.1e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 CRK28223.1 - 1.1e-09 39.4 0.0 2e-09 38.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.19 CRK28223.1 - 0.0033 16.7 0.2 0.0052 16.1 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain HTH_psq PF05225.16 CRK28223.1 - 0.081 12.7 0.1 2.1 8.2 0.1 2.3 2 0 0 2 2 2 0 helix-turn-helix, Psq domain Staph_opine_DH PF10100.9 CRK28223.1 - 0.14 10.8 0.0 0.19 10.3 0.0 1.2 1 0 0 1 1 1 0 Staphylopine dehydrogenase NCA2 PF08637.10 CRK28224.1 - 1.5e-109 365.7 0.0 3.8e-109 364.3 0.0 1.7 2 0 0 2 2 2 1 ATP synthase regulation protein NCA2 FA_hydroxylase PF04116.13 CRK28225.1 - 3.9e-25 88.7 16.4 3.9e-25 88.7 16.4 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Pterin_4a PF01329.19 CRK28226.1 - 1.7e-23 82.6 0.0 2.3e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase PCSK9_C3 PF18463.1 CRK28226.1 - 0.064 13.5 2.0 0.16 12.2 2.0 1.8 1 1 0 1 1 1 0 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain bZIP_1 PF00170.21 CRK28227.1 - 1.4e-08 34.7 6.9 2.7e-08 33.8 6.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor DUF3158 PF11358.8 CRK28227.1 - 0.0084 15.9 0.1 0.015 15.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3158) Presenilin PF01080.17 CRK28227.1 - 5.5 5.6 8.5 7.9 5.1 8.5 1.3 1 0 0 1 1 1 0 Presenilin Actin PF00022.19 CRK28228.1 - 2.9e-53 181.0 0.0 4.1e-32 111.3 0.0 2.2 2 0 0 2 2 2 2 Actin DASH_Dad4 PF08650.10 CRK28230.1 - 1.3e-33 114.7 6.0 1.5e-33 114.6 6.0 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 GM_CSF PF01109.17 CRK28230.1 - 0.064 13.4 0.3 0.072 13.3 0.3 1.1 1 0 0 1 1 1 0 Granulocyte-macrophage colony-stimulating factor LTD PF00932.19 CRK28230.1 - 0.12 12.7 0.1 0.13 12.7 0.1 1.1 1 0 0 1 1 1 0 Lamin Tail Domain YL1_C PF08265.11 CRK28231.1 - 4.9e-16 58.2 0.3 7.9e-16 57.5 0.3 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Got1 PF04178.12 CRK28232.1 - 7.5e-15 55.3 11.9 9.4e-15 55.0 11.9 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family Profilin PF00235.19 CRK28233.1 - 3.5e-46 156.6 0.7 3.9e-46 156.4 0.7 1.0 1 0 0 1 1 1 1 Profilin K_trans PF02705.16 CRK28234.1 - 3.1e-182 606.8 13.3 3.7e-182 606.6 13.3 1.0 1 0 0 1 1 1 1 K+ potassium transporter TAT_signal PF10518.9 CRK28234.1 - 0.051 13.4 0.2 0.13 12.1 0.2 1.8 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence GMP_synt_C PF00958.22 CRK28235.1 - 8.2e-33 112.3 0.0 1.7e-32 111.3 0.0 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 CRK28235.1 - 9.7e-33 113.5 0.0 1.6e-32 112.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 CRK28235.1 - 2.2e-08 33.5 0.0 1.7e-05 24.0 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 CRK28235.1 - 1.2e-05 25.2 0.0 2.1e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.16 CRK28235.1 - 0.0018 17.1 0.0 0.0035 16.2 0.0 1.4 1 0 0 1 1 1 1 tRNA methyl transferase QueC PF06508.13 CRK28235.1 - 0.023 14.2 0.0 0.1 12.1 0.0 1.9 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC PAPS_reduct PF01507.19 CRK28235.1 - 0.043 13.8 0.0 0.076 13.1 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Arginosuc_synth PF00764.19 CRK28235.1 - 0.12 11.6 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 Arginosuccinate synthase ThiI PF02568.14 CRK28235.1 - 0.19 11.3 0.0 0.45 10.1 0.0 1.6 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) Fungal_trans PF04082.18 CRK28237.1 - 2.7e-20 72.5 0.0 4e-20 72.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK28237.1 - 8.5e-09 35.4 8.9 1.6e-08 34.6 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Porphobil_deam PF01379.20 CRK28237.1 - 0.091 12.3 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Porphobilinogen deaminase, dipyromethane cofactor binding domain FAD_binding_3 PF01494.19 CRK28238.1 - 3.9e-13 49.4 0.8 1.1e-12 47.8 0.8 1.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 CRK28238.1 - 1.3e-05 24.9 2.9 0.002 17.8 0.1 2.6 2 1 1 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CRK28238.1 - 4.3e-05 22.9 0.3 0.0021 17.4 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CRK28238.1 - 4.4e-05 24.0 0.2 0.0007 20.1 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CRK28238.1 - 0.00037 19.9 0.0 0.17 11.1 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase CoA_transf_3 PF02515.17 CRK28238.1 - 0.00059 19.1 0.1 0.00091 18.4 0.1 1.3 1 0 0 1 1 1 1 CoA-transferase family III NAD_binding_8 PF13450.6 CRK28238.1 - 0.0059 16.8 0.0 0.019 15.2 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 CRK28238.1 - 0.008 15.6 1.3 0.013 14.9 0.3 1.9 2 1 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 CRK28238.1 - 0.063 12.6 0.2 0.098 11.9 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 CRK28238.1 - 0.1 12.3 0.1 0.67 9.6 0.0 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.14 CRK28238.1 - 0.21 10.4 0.6 9.7 4.9 0.1 2.3 3 0 0 3 3 3 0 Tryptophan halogenase eIF3_subunit PF08597.10 CRK28240.1 - 0.0022 17.9 1.2 0.0026 17.7 1.2 1.1 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit KH_8 PF17903.1 CRK28240.1 - 0.086 13.0 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Krr1 KH1 domain Cyto_heme_lyase PF01265.17 CRK28243.1 - 3.1e-119 397.9 0.6 4.9e-119 397.2 0.6 1.3 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase Oxidored_FMN PF00724.20 CRK28245.1 - 1.7e-47 162.4 0.0 2.2e-47 162.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 CRK28245.1 - 1.3e-08 34.3 0.0 5.8e-08 32.2 0.0 1.8 1 1 1 2 2 2 1 Dihydrouridine synthase (Dus) AP_endonuc_2 PF01261.24 CRK28245.1 - 0.0015 18.0 0.3 3.8 6.9 0.0 3.3 2 1 1 3 3 3 3 Xylose isomerase-like TIM barrel Radical_SAM PF04055.21 CRK28245.1 - 0.036 14.5 0.0 0.058 13.8 0.0 1.3 1 0 0 1 1 1 0 Radical SAM superfamily MTHFR PF02219.17 CRK28245.1 - 0.12 11.6 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Methylenetetrahydrofolate reductase Anthrax_toxA PF03497.16 CRK28246.1 - 0.044 13.9 0.1 0.053 13.7 0.1 1.1 1 0 0 1 1 1 0 Anthrax toxin LF subunit p450 PF00067.22 CRK28246.1 - 0.075 11.8 0.8 0.089 11.5 0.8 1.0 1 0 0 1 1 1 0 Cytochrome P450 UBN_AB PF14075.6 CRK28246.1 - 0.098 12.4 4.8 0.12 12.1 4.8 1.1 1 0 0 1 1 1 0 Ubinuclein conserved middle domain H_lectin PF09458.10 CRK28248.1 - 0.00097 19.3 0.0 0.0014 18.8 0.0 1.3 1 0 0 1 1 1 1 H-type lectin domain Glyco_hydro_115 PF15979.5 CRK28250.1 - 5.8e-127 423.8 0.5 7.4e-127 423.4 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 CRK28250.1 - 7e-43 146.4 0.0 1.2e-42 145.7 0.0 1.4 1 0 0 1 1 1 1 Gylcosyl hydrolase family 115 C-terminal domain Chorion_3 PF05387.11 CRK28251.1 - 3.6 7.2 8.4 28 4.2 7.9 2.1 2 0 0 2 2 2 0 Chorion family 3 DbpA PF03880.15 CRK28253.1 - 0.01 15.8 0.1 0.021 14.8 0.1 1.6 1 0 0 1 1 1 0 DbpA RNA binding domain RRM_1 PF00076.22 CRK28253.1 - 0.1 12.5 0.0 0.3 10.9 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SLT_2 PF13406.6 CRK28253.1 - 1.2 8.4 6.1 0.084 12.1 0.4 1.8 2 0 0 2 2 2 0 Transglycosylase SLT domain MFS_1 PF07690.16 CRK28254.1 - 2.6e-33 115.4 67.7 5.9e-25 87.9 32.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Tyrosinase PF00264.20 CRK28256.1 - 1.1e-41 143.5 2.7 1.6e-41 143.0 2.0 1.5 2 0 0 2 2 2 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 CRK28256.1 - 0.011 16.3 0.1 0.069 13.8 0.1 2.0 1 1 0 1 1 1 0 Tyosinase C-terminal domain Dioxygenase_C PF00775.21 CRK28257.1 - 4.5e-06 26.2 0.1 7.3e-06 25.5 0.1 1.3 1 0 0 1 1 1 1 Dioxygenase AA_permease PF00324.21 CRK28259.1 - 1.7e-10 40.1 1.4 2.3e-10 39.7 1.4 1.1 1 0 0 1 1 1 1 Amino acid permease EMC3_TMCO1 PF01956.16 CRK28259.1 - 0.08 12.7 0.3 0.11 12.2 0.3 1.1 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Fumble PF03630.14 CRK28260.1 - 1.2e-23 83.8 0.0 1.5e-23 83.5 0.0 1.1 1 0 0 1 1 1 1 Fumble Pmp3 PF01679.17 CRK28261.1 - 7.3e-25 86.9 8.1 8.1e-25 86.8 8.1 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator TM_helix PF05552.12 CRK28261.1 - 1.3 9.0 6.4 2.4 8.2 3.1 2.0 2 0 0 2 2 2 0 Conserved TM helix MMR_HSR1_C PF08438.10 CRK28263.1 - 1.2e-15 58.0 0.1 2.4e-15 57.0 0.1 1.5 1 0 0 1 1 1 1 GTPase of unknown function C-terminal TRP PF06011.12 CRK28263.1 - 4.2e-15 55.4 16.0 1.3e-10 40.6 14.7 2.2 2 0 0 2 2 2 2 Transient receptor potential (TRP) ion channel MMR_HSR1 PF01926.23 CRK28263.1 - 2.6e-07 30.7 0.0 6.5e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GDPD PF03009.17 CRK28264.1 - 2.6e-26 92.9 0.0 3.8e-26 92.4 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family IFRD PF05004.13 CRK28265.1 - 1.8e-56 191.5 6.8 5.3e-40 137.4 0.3 2.1 1 1 1 2 2 2 2 Interferon-related developmental regulator (IFRD) RAP1 PF07218.11 CRK28265.1 - 4.9 5.3 5.5 7.2 4.8 5.5 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) FHA PF00498.26 CRK28266.1 - 9.7e-14 51.5 0.0 1.9e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 FHA domain WD40 PF00400.32 CRK28267.1 - 1.3e-39 133.4 19.2 5.5e-10 39.7 0.0 8.0 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK28267.1 - 4.9e-14 52.4 0.7 0.0092 16.3 0.0 4.9 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CRK28267.1 - 4e-08 32.6 0.4 0.23 10.4 0.0 4.7 2 1 2 4 4 4 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CRK28267.1 - 1.3e-06 27.4 2.5 0.5 8.9 0.1 4.3 3 1 0 3 3 3 3 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 CRK28267.1 - 4.2e-05 22.7 0.2 4.2e-05 22.7 0.2 2.8 3 1 1 4 4 4 1 Partner and localizer of BRCA2 WD40 domain Frtz PF11768.8 CRK28267.1 - 0.00055 18.4 0.0 0.0027 16.1 0.0 2.0 2 1 1 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz HPS3_N PF14761.6 CRK28267.1 - 0.0023 17.5 0.0 0.049 13.2 0.0 2.5 2 1 1 3 3 3 1 Hermansky-Pudlak syndrome 3 DUF1513 PF07433.11 CRK28267.1 - 0.004 16.3 0.5 2.2 7.3 0.0 3.4 1 1 2 4 4 4 1 Protein of unknown function (DUF1513) Hira PF07569.11 CRK28267.1 - 0.073 12.8 1.3 24 4.6 0.2 3.2 1 1 1 2 2 2 0 TUP1-like enhancer of split Pkinase PF00069.25 CRK28268.1 - 2e-12 47.0 0.0 5.9e-12 45.5 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain HEAT PF02985.22 CRK28268.1 - 2.9e-10 39.5 2.4 0.084 13.2 0.0 5.5 6 1 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.6 CRK28268.1 - 3.9e-07 30.4 0.1 0.0014 19.1 0.1 3.4 3 0 0 3 3 3 2 HEAT-like repeat Cnd1 PF12717.7 CRK28268.1 - 1.7e-05 24.9 0.0 0.0001 22.4 0.0 2.0 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CRK28268.1 - 2.1e-05 24.8 0.5 0.026 14.9 0.0 3.9 3 1 2 5 5 5 2 HEAT repeats Pkinase_Tyr PF07714.17 CRK28268.1 - 0.00015 21.1 0.0 0.00025 20.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase COPIIcoated_ERV PF07970.12 CRK28270.1 - 1.2e-25 90.7 0.0 1.2e-25 90.7 0.0 2.3 2 0 0 2 2 2 1 Endoplasmic reticulum vesicle transporter Aconitase PF00330.20 CRK28270.1 - 2.8e-14 53.0 0.0 4e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) ZZ PF00569.17 CRK28270.1 - 3.3e-13 49.2 50.2 1e-05 25.2 11.3 3.4 3 0 0 3 3 3 3 Zinc finger, ZZ type C1_2 PF03107.16 CRK28270.1 - 8.3e-05 22.8 40.5 0.058 13.7 5.5 3.4 3 0 0 3 3 3 3 C1 domain Diphthamide_syn PF01866.17 CRK28272.1 - 9.8e-18 64.6 0.2 1.2e-17 64.3 0.2 1.2 1 0 0 1 1 1 1 Putative diphthamide synthesis protein AMPK1_CBM PF16561.5 CRK28274.1 - 0.0056 16.9 0.3 0.0098 16.1 0.3 1.5 1 1 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase PhoD_N PF16655.5 CRK28274.1 - 0.07 13.7 0.0 0.095 13.2 0.0 1.2 1 0 0 1 1 1 0 PhoD-like phosphatase, N-terminal domain CBM_20 PF00686.19 CRK28274.1 - 0.077 12.9 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 Starch binding domain AIM24 PF01987.17 CRK28275.1 - 4e-51 173.7 0.2 4.8e-51 173.4 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Amidohydro_2 PF04909.14 CRK28276.1 - 1.3e-18 67.9 0.1 1.5e-18 67.6 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase AIM24 PF01987.17 CRK28278.1 - 2.8e-23 82.8 0.1 4e-23 82.3 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Macoilin PF09726.9 CRK28280.1 - 4.1 5.8 6.9 2.5 6.6 2.0 2.1 2 0 0 2 2 2 0 Macoilin family TRP PF06011.12 CRK28281.1 - 1.1e-158 528.5 35.2 1.1e-158 528.5 35.2 1.4 2 0 0 2 2 2 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 CRK28281.1 - 6.8e-42 143.1 0.6 1.8e-41 141.8 0.4 1.8 2 0 0 2 2 2 1 ML-like domain E1_DerP2_DerF2 PF02221.15 CRK28281.1 - 0.018 15.5 0.1 0.034 14.6 0.1 1.5 1 0 0 1 1 1 0 ML domain Ribonuc_L-PSP PF01042.21 CRK28282.1 - 5.1e-34 116.9 0.1 6.1e-34 116.6 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Phlebovirus_G2 PF07245.11 CRK28282.1 - 0.00088 17.9 0.0 0.00088 17.9 0.0 1.1 1 0 0 1 1 1 1 Phlebovirus glycoprotein G2 DUF3433 PF11915.8 CRK28284.1 - 3.3e-29 101.2 10.2 4.9e-19 68.6 2.3 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) VirB3 PF05101.13 CRK28284.1 - 0.28 11.4 2.4 1.3 9.3 2.4 2.1 1 0 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein GvpG PF05120.12 CRK28285.1 - 0.0097 15.9 6.8 0.0097 15.9 6.8 2.2 1 1 1 2 2 2 1 Gas vesicle protein G Atg14 PF10186.9 CRK28285.1 - 0.014 14.5 7.8 0.018 14.1 7.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 LMBR1 PF04791.16 CRK28285.1 - 0.15 10.9 4.6 0.18 10.7 4.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DotU PF09850.9 CRK28285.1 - 0.17 11.6 7.7 0.19 11.4 2.8 2.2 2 0 0 2 2 2 0 Type VI secretion system protein DotU FUSC PF04632.12 CRK28285.1 - 0.34 9.4 12.1 0.43 9.1 12.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family FapA PF03961.13 CRK28285.1 - 0.48 9.0 7.1 0.82 8.2 7.1 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A Fmp27_WPPW PF10359.9 CRK28285.1 - 0.97 8.2 9.5 1.3 7.8 9.5 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain TPR_MLP1_2 PF07926.12 CRK28285.1 - 1.2 9.2 24.8 1.6 8.8 3.9 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein ERM PF00769.19 CRK28285.1 - 1.7 8.4 30.9 2.4 7.9 29.8 1.4 1 1 0 1 1 1 0 Ezrin/radixin/moesin family AAA_13 PF13166.6 CRK28285.1 - 1.9 7.1 12.1 3.1 6.3 12.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 CRK28285.1 - 2.6 7.7 10.3 3.9 7.2 10.3 1.3 1 0 0 1 1 1 0 AAA domain Fez1 PF06818.15 CRK28285.1 - 2.9 8.3 20.4 4 7.9 20.4 1.1 1 0 0 1 1 1 0 Fez1 V_ATPase_I PF01496.19 CRK28285.1 - 3 5.6 10.0 3.9 5.3 10.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Golgin_A5 PF09787.9 CRK28285.1 - 3.2 7.2 19.7 4.2 6.7 19.7 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 PFEMP PF03011.15 CRK28285.1 - 3.4 8.3 8.1 4.8 7.8 8.1 1.3 1 0 0 1 1 1 0 PFEMP DBL domain Fib_alpha PF08702.10 CRK28285.1 - 3.9 7.6 12.6 13 6.0 4.8 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family ALMT PF11744.8 CRK28285.1 - 5 5.8 8.9 6.1 5.6 8.9 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter CSN5_C PF18323.1 CRK28285.1 - 5.1 8.1 11.0 27 5.8 9.8 2.5 1 1 1 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain CHDCT2 PF08074.11 CRK28285.1 - 9.1 6.4 10.4 22 5.2 10.4 1.6 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain Vac7 PF12751.7 CRK28287.1 - 1.8e-156 521.4 0.9 1.8e-156 521.4 0.9 2.0 2 1 0 2 2 2 1 Vacuolar segregation subunit 7 NCA2 PF08637.10 CRK28288.1 - 2.4e-43 148.4 0.0 2.6e-43 148.2 0.0 1.0 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 IF-2B PF01008.17 CRK28289.1 - 4.1e-11 42.6 0.1 4.4e-11 42.5 0.1 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family PikAIV_N PF18605.1 CRK28289.1 - 0.089 12.4 0.2 2.9 7.6 0.1 2.3 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain PHO4 PF01384.20 CRK28290.1 - 1.3e-21 77.1 0.1 1.4e-21 77.0 0.1 1.0 1 0 0 1 1 1 1 Phosphate transporter family PTPA PF03095.15 CRK28292.1 - 1.3e-76 258.0 0.0 1.5e-76 257.8 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Fungal_trans PF04082.18 CRK28293.1 - 2.2e-06 26.9 0.0 3.2e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK28293.1 - 7.8e-06 25.9 13.7 2.1e-05 24.6 13.7 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FMO-like PF00743.19 CRK28294.1 - 8e-10 37.7 0.3 1.2e-08 33.8 0.0 2.2 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 CRK28294.1 - 1.4e-08 34.3 0.1 3.5e-05 23.2 0.0 3.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CRK28294.1 - 1.7e-08 34.1 1.2 1.4e-07 31.1 0.0 2.3 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CRK28294.1 - 3.9e-07 29.5 0.1 2.7e-05 23.5 0.0 2.7 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 CRK28294.1 - 0.00053 19.3 0.0 0.037 13.3 0.0 2.6 3 0 0 3 3 3 1 Thi4 family DAO PF01266.24 CRK28294.1 - 0.0031 17.2 2.7 0.0095 15.5 0.4 2.7 1 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 CRK28294.1 - 0.0031 18.0 0.1 3.6 8.2 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CRK28294.1 - 0.0084 16.3 0.1 0.54 10.5 0.0 2.9 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 CRK28294.1 - 0.02 14.0 0.1 13 4.7 0.0 3.5 3 1 1 4 4 4 0 Lycopene cyclase protein Shikimate_DH PF01488.20 CRK28294.1 - 0.064 13.3 0.0 0.46 10.5 0.0 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 CRK28294.1 - 0.17 11.1 0.1 4.2 6.5 0.0 2.7 3 1 1 4 4 4 0 FAD binding domain Abhydrolase_3 PF07859.13 CRK28295.1 - 5.2e-31 108.2 0.0 6.3e-31 107.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 CRK28295.1 - 1.4e-09 37.3 0.0 1.7e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase NAD_binding_10 PF13460.6 CRK28297.1 - 6.3e-08 32.7 0.0 1.2e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H-binding ABC2_membrane PF01061.24 CRK28299.1 - 3.6e-69 232.4 60.9 2.6e-41 141.3 20.4 3.3 3 1 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 CRK28299.1 - 7.7e-34 117.1 0.0 4.8e-16 59.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 CRK28299.1 - 1.9e-33 114.2 10.5 4e-29 100.4 0.0 3.9 4 0 0 4 4 2 2 CDR ABC transporter ABC_trans_N PF14510.6 CRK28299.1 - 4.1e-10 40.1 0.0 1.2e-09 38.7 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_25 PF13481.6 CRK28299.1 - 9.7e-07 28.5 0.1 0.0014 18.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CRK28299.1 - 2.2e-06 28.2 0.4 0.1 13.0 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 CRK28299.1 - 1e-05 25.5 0.1 0.11 12.3 0.1 3.4 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 CRK28299.1 - 3.8e-05 23.7 0.1 0.012 15.5 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 CRK28299.1 - 4.6e-05 23.6 0.1 0.025 14.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CRK28299.1 - 6.2e-05 22.7 0.9 0.038 13.7 0.2 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 CRK28299.1 - 7.4e-05 23.3 0.0 0.048 14.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 CRK28299.1 - 0.003 16.7 12.6 0.003 16.7 12.6 3.5 3 1 0 3 3 3 2 ABC-2 family transporter protein PDR_assoc PF08370.11 CRK28299.1 - 0.0093 15.7 1.0 0.45 10.3 0.1 3.1 2 0 0 2 2 2 1 Plant PDR ABC transporter associated AAA_22 PF13401.6 CRK28299.1 - 0.015 15.6 0.4 6.8 7.0 0.1 2.7 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 CRK28299.1 - 0.021 15.2 0.2 4.4 7.7 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 CRK28299.1 - 0.057 13.8 0.5 9.1 6.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 CRK28299.1 - 0.062 13.0 0.1 10 5.8 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein Rad17 PF03215.15 CRK28299.1 - 0.063 13.2 0.0 0.65 9.9 0.0 2.1 2 0 0 2 2 2 0 Rad17 P-loop domain SMC_N PF02463.19 CRK28299.1 - 0.11 11.9 0.0 1.6 8.1 0.0 2.6 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain NACHT PF05729.12 CRK28299.1 - 0.11 12.4 0.4 18 5.2 0.0 2.6 2 0 0 2 2 2 0 NACHT domain cobW PF02492.19 CRK28299.1 - 0.18 11.4 2.6 8.2 6.0 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 CRK28299.1 - 0.19 11.4 0.1 17 5.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 CRK28299.1 - 0.23 11.7 1.9 20 5.4 0.1 2.6 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 CRK28299.1 - 0.29 11.2 1.0 21 5.2 0.2 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase Pkinase PF00069.25 CRK28302.1 - 6.6e-18 65.0 0.0 3.1e-08 33.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CRK28302.1 - 1.1e-07 31.4 0.0 0.0056 16.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CRK28302.1 - 0.0041 17.1 0.0 0.0077 16.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CRK28302.1 - 0.0046 15.8 0.0 0.0064 15.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CRK28302.1 - 0.018 14.4 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CRK28302.1 - 0.034 13.7 0.0 0.068 12.8 0.0 1.4 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 CRK28302.1 - 0.035 13.7 0.0 0.052 13.2 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 DUF3176 PF11374.8 CRK28304.1 - 0.0015 18.7 0.6 0.0032 17.7 0.6 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) GFO_IDH_MocA PF01408.22 CRK28307.1 - 5.8e-18 65.8 0.0 9.9e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 CRK28307.1 - 0.0015 18.6 0.0 0.0029 17.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Sacchrp_dh_NADP PF03435.18 CRK28307.1 - 0.044 14.0 0.0 0.097 12.9 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Sortilin-Vps10 PF15902.5 CRK28320.1 - 0.0034 16.3 0.1 0.0036 16.2 0.1 1.1 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, BNR PF02012.20 CRK28320.1 - 0.022 14.7 1.8 3 8.2 0.2 3.0 3 0 0 3 3 3 0 BNR/Asp-box repeat RNase_P_pop3 PF08228.11 CRK28323.1 - 0.1 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 RNase P subunit Pop3 DUF3517 PF12030.8 CRK28324.1 - 3e-95 319.0 0.0 6.3e-95 317.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3517) UCH PF00443.29 CRK28324.1 - 1.3e-40 139.6 1.3 2.4e-40 138.6 1.3 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CRK28324.1 - 2.7e-19 69.9 1.0 5.4e-19 68.9 1.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Unstab_antitox PF09720.10 CRK28324.1 - 0.024 14.7 0.0 0.12 12.4 0.0 2.3 1 0 0 1 1 1 0 Putative addiction module component DUF3517 PF12030.8 CRK28325.1 - 6.2e-96 321.2 0.0 8.1e-96 320.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3517) PRCC PF10253.9 CRK28326.1 - 1.2e-34 121.0 16.7 1.2e-34 121.0 16.7 3.5 2 1 1 3 3 3 1 Mitotic checkpoint regulator, MAD2B-interacting CRIM PF16978.5 CRK28327.1 - 2.9e-45 153.9 0.0 1.1e-44 152.1 0.0 1.9 2 0 0 2 2 2 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 CRK28327.1 - 3.2e-24 85.3 0.2 7.7e-24 84.1 0.2 1.6 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology TUG-UBL1 PF11470.8 CRK28327.1 - 0.00076 19.7 0.0 0.0021 18.2 0.0 1.7 1 0 0 1 1 1 1 TUG ubiquitin-like domain PH PF00169.29 CRK28327.1 - 0.017 15.6 0.0 0.035 14.6 0.0 1.5 1 0 0 1 1 1 0 PH domain DUF2884 PF11101.8 CRK28328.1 - 0.058 12.9 0.2 0.074 12.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) Glyco_trans_2_3 PF13632.6 CRK28330.1 - 3.9e-47 160.7 1.8 1.2e-46 159.2 1.8 1.8 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 CRK28330.1 - 3.5e-06 26.9 0.0 3.2e-05 23.8 0.0 2.3 2 1 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 CRK28330.1 - 0.00048 19.6 0.0 0.0015 18.1 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 CRK28330.1 - 0.012 15.5 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Chitin_synth_2 PF03142.15 CRK28330.1 - 0.029 13.0 0.0 0.067 11.8 0.0 1.5 1 0 0 1 1 1 0 Chitin synthase IncE PF17627.2 CRK28330.1 - 0.24 11.4 2.1 0.52 10.3 2.1 1.5 1 0 0 1 1 1 0 Inclusion membrane protein E PQQ PF01011.21 CRK28334.1 - 0.052 13.5 0.0 0.078 12.9 0.0 1.3 1 0 0 1 1 1 0 PQQ enzyme repeat Ribonuc_L-PSP PF01042.21 CRK28335.1 - 2.9e-19 69.3 0.0 3.4e-19 69.0 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP DOCK_N PF16172.5 CRK28336.1 - 6.6e-125 416.9 0.0 1e-124 416.3 0.0 1.3 1 0 0 1 1 1 1 DOCK N-terminus DOCK-C2 PF14429.6 CRK28336.1 - 2.8e-30 105.6 0.0 8.5e-30 104.0 0.0 1.9 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins DHR-2 PF06920.13 CRK28336.1 - 1.1e-29 103.5 0.5 7.8e-29 100.7 0.5 2.0 1 1 0 1 1 1 1 Dock homology region 2 SH3_1 PF00018.28 CRK28336.1 - 7.9e-05 22.2 0.0 0.00017 21.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CRK28336.1 - 0.00019 21.2 0.0 0.00091 19.0 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 CRK28336.1 - 0.067 12.9 0.0 0.18 11.5 0.0 1.8 1 0 0 1 1 1 0 Variant SH3 domain PAP2_3 PF14378.6 CRK28337.1 - 6.5e-34 117.3 19.5 7.7e-27 94.2 4.2 2.8 3 0 0 3 3 3 2 PAP2 superfamily PAP2 PF01569.21 CRK28337.1 - 0.00061 19.6 2.3 0.00061 19.6 2.3 2.6 2 1 1 3 3 3 1 PAP2 superfamily PAP2_C PF14360.6 CRK28337.1 - 0.49 11.0 5.4 0.16 12.5 0.4 2.5 2 0 0 2 2 2 0 PAP2 superfamily C-terminal fn3_3 PF14686.6 CRK28338.1 - 1.8e-23 82.1 1.5 1.2e-22 79.5 0.0 2.8 3 0 0 3 3 3 1 Polysaccharide lyase family 4, domain II CBM-like PF14683.6 CRK28338.1 - 8e-19 68.1 0.4 3.8e-18 65.9 0.1 2.2 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain III MLTR_LBD PF17765.1 CRK28338.1 - 0.0078 16.4 0.1 0.39 10.8 0.0 2.5 3 0 0 3 3 3 1 MmyB-like transcription regulator ligand binding domain Fungal_trans_2 PF11951.8 CRK28339.1 - 6.2e-18 64.8 2.8 1.1e-17 63.9 2.8 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Glyco_transf_52 PF07922.11 CRK28339.1 - 0.043 13.1 0.0 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 52 FtsA PF14450.6 CRK28339.1 - 0.068 13.6 0.0 6.4 7.3 0.0 2.3 2 0 0 2 2 2 0 Cell division protein FtsA Aa_trans PF01490.18 CRK28340.1 - 4.1e-38 131.2 33.5 4.7e-38 131.0 33.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Herpes_teg_N PF04843.12 CRK28340.1 - 0.22 11.2 0.0 0.38 10.4 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus tegument protein, N-terminal conserved region FMN_dh PF01070.18 CRK28341.1 - 5.6e-76 255.8 1.5 1.6e-51 175.4 0.2 3.1 2 1 1 3 3 3 3 FMN-dependent dehydrogenase IMPDH PF00478.25 CRK28341.1 - 0.00081 18.5 0.0 0.0014 17.7 0.0 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 CRK28341.1 - 0.0017 17.8 0.2 0.32 10.4 0.0 2.5 1 1 1 2 2 2 2 Histidine biosynthesis protein Glu_synthase PF01645.17 CRK28341.1 - 0.0068 15.6 0.0 0.01 15.0 0.0 1.1 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 CRK28341.1 - 0.019 14.4 0.1 0.04 13.3 0.1 1.5 1 0 0 1 1 1 0 Nitronate monooxygenase Peptidase_M19 PF01244.21 CRK28341.1 - 0.059 12.5 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Membrane dipeptidase (Peptidase family M19) DHO_dh PF01180.21 CRK28341.1 - 0.18 11.0 0.0 0.7 9.0 0.0 1.8 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase VCBS PF13517.6 CRK28342.1 - 3.5e-29 101.2 35.9 2e-10 41.1 2.5 7.8 3 2 4 8 8 8 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Lipase_GDSL_2 PF13472.6 CRK28342.1 - 7.8e-12 45.9 0.1 1.6e-11 44.9 0.1 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family TcdB_toxin_midN PF12256.8 CRK28342.1 - 5e-09 35.8 9.6 0.34 10.3 0.0 6.6 5 2 2 7 7 7 4 Insecticide toxin TcdB middle/N-terminal region FG-GAP PF01839.23 CRK28342.1 - 8.2e-05 22.6 36.4 0.53 10.5 0.8 7.1 7 0 0 7 7 7 5 FG-GAP repeat Lipase_GDSL PF00657.22 CRK28342.1 - 0.00096 19.2 0.0 0.002 18.1 0.0 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 CRK28342.1 - 0.0017 18.5 0.0 0.0033 17.6 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family PliI PF16743.5 CRK28342.1 - 0.025 14.3 0.1 14 5.4 0.0 3.9 5 0 0 5 5 5 0 Periplasmic lysozyme inhibitor of I-type lysozyme Dockerin_1 PF00404.18 CRK28342.1 - 0.32 11.2 11.8 22 5.4 0.1 5.2 5 0 0 5 5 5 0 Dockerin type I domain AMP-binding PF00501.28 CRK28343.1 - 6e-72 242.6 0.0 9.8e-72 241.8 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 CRK28343.1 - 2.2e-62 210.5 0.0 3.4e-62 209.9 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 CRK28343.1 - 1.2e-10 41.2 0.0 2.3e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 CRK28343.1 - 3.5e-08 33.7 0.0 7.3e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 CRK28343.1 - 5.5e-08 32.1 0.0 9.3e-08 31.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 CRK28343.1 - 4.3e-06 26.7 0.1 2.2e-05 24.5 0.1 2.3 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 CRK28343.1 - 9e-05 22.0 0.0 0.00014 21.4 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase AMP-binding_C PF13193.6 CRK28343.1 - 0.0033 18.4 0.0 0.013 16.5 0.0 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain adh_short PF00106.25 CRK28343.1 - 0.1 12.1 0.0 0.23 10.9 0.0 1.6 1 0 0 1 1 1 0 short chain dehydrogenase PSII_Pbs27 PF13326.6 CRK28343.1 - 0.11 12.8 0.1 8.6 6.7 0.0 2.6 2 0 0 2 2 2 0 Photosystem II Pbs27 AsmA PF05170.14 CRK28344.1 - 0.16 10.8 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 AsmA family Response_reg PF00072.24 CRK28345.1 - 4.6e-21 75.1 0.0 9.1e-21 74.1 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 CRK28345.1 - 1.2e-20 74.1 0.0 2.3e-20 73.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 CRK28345.1 - 1.2e-09 38.1 0.0 3e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Pectinesterase PF01095.19 CRK28347.1 - 1.2e-66 224.5 6.5 6.5e-38 130.1 0.1 4.8 4 2 1 5 5 5 2 Pectinesterase RPA_C PF08784.11 CRK28348.1 - 4.6e-22 78.6 0.8 4.6e-22 78.6 0.8 1.7 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 CRK28348.1 - 1.2e-05 25.2 0.7 5.4e-05 23.1 0.3 2.2 2 1 0 2 2 2 1 OB-fold nucleic acid binding domain CBM_35 PF16990.5 CRK28348.1 - 0.25 11.6 3.2 0.81 10.0 0.6 2.2 2 0 0 2 2 2 0 Carbohydrate binding module (family 35) RIO1 PF01163.22 CRK28349.1 - 8.1e-39 133.2 0.3 8.4e-27 94.0 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Rio2_N PF09202.11 CRK28349.1 - 3.7e-28 97.5 0.0 8.7e-28 96.4 0.0 1.7 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.23 CRK28349.1 - 4.4e-07 30.1 0.2 0.00054 19.9 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 CRK28349.1 - 1e-05 25.0 0.1 0.00031 20.2 0.1 2.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family NOA36 PF06524.12 CRK28349.1 - 0.54 9.5 8.3 0.78 9.0 8.3 1.2 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.6 CRK28349.1 - 6.6 6.4 6.5 11 5.6 6.5 1.3 1 0 0 1 1 1 0 FAM176 family RPN1_RPN2_N PF17781.1 CRK28350.1 - 1.1e-110 369.9 2.5 1.8e-110 369.2 2.5 1.3 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 CRK28350.1 - 1.6e-29 101.7 0.0 2.9e-29 100.9 0.0 1.4 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 CRK28350.1 - 2.3e-18 65.6 19.4 6e-06 26.4 0.1 8.4 8 1 0 8 8 8 4 Proteasome/cyclosome repeat HEAT_2 PF13646.6 CRK28350.1 - 4.8e-08 33.3 0.4 0.02 15.3 0.0 3.8 4 1 1 5 5 5 3 HEAT repeats IFRD PF05004.13 CRK28350.1 - 0.063 12.4 4.1 0.5 9.4 0.1 3.5 3 1 0 3 3 3 0 Interferon-related developmental regulator (IFRD) Herpes_UL95 PF03038.14 CRK28350.1 - 0.082 12.0 0.1 0.15 11.1 0.1 1.3 1 0 0 1 1 1 0 UL95 family HAND PF09110.11 CRK28350.1 - 0.088 13.6 2.0 0.22 12.3 2.0 1.6 1 0 0 1 1 1 0 HAND MatE PF01554.18 CRK28351.1 - 7.8e-44 149.2 21.4 5.2e-29 101.0 7.8 2.3 2 0 0 2 2 2 2 MatE RRM_1 PF00076.22 CRK28353.1 - 6.4e-21 74.0 0.0 5e-09 35.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAD_binding_1 PF00667.20 CRK28354.1 - 8.7e-62 208.6 0.0 1.2e-61 208.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 CRK28354.1 - 3.1e-19 69.6 0.0 5.3e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_1 PF00258.25 CRK28354.1 - 9e-13 48.6 0.8 2.3e-12 47.3 0.2 1.9 2 0 0 2 2 2 1 Flavodoxin MOR2-PAG1_N PF14222.6 CRK28355.1 - 2.5e-216 719.9 0.0 4.8e-216 719.0 0.0 1.5 2 0 0 2 2 2 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 CRK28355.1 - 3.1e-95 318.8 0.5 3.1e-95 318.8 0.5 1.8 2 0 0 2 2 2 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 CRK28355.1 - 1.2e-18 66.3 4.9 2.7e-12 45.2 0.1 3.4 1 1 2 3 3 3 3 Cell morphogenesis central region HEAT_2 PF13646.6 CRK28355.1 - 0.0049 17.2 2.3 0.94 9.9 0.1 5.1 6 0 0 6 6 6 1 HEAT repeats HEAT PF02985.22 CRK28355.1 - 0.089 13.1 4.4 0.23 11.8 0.0 4.0 4 0 0 4 4 4 0 HEAT repeat DIM1 PF02966.16 CRK28356.1 - 3.8e-68 227.3 0.1 4.3e-68 227.2 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 CRK28356.1 - 0.027 14.5 0.0 0.034 14.1 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin Npa1 PF11707.8 CRK28357.1 - 1.2e-74 251.7 0.0 1.8e-74 251.1 0.0 1.2 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal MOR2-PAG1_mid PF14228.6 CRK28357.1 - 5.4e-17 60.8 0.0 7.3e-17 60.4 0.0 1.0 1 0 0 1 1 1 1 Cell morphogenesis central region Cutinase PF01083.22 CRK28361.1 - 3.6e-05 23.8 0.0 4.4e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Cutinase LRR_8 PF13855.6 CRK28362.1 - 3.4e-29 100.4 47.3 3.3e-06 26.8 0.1 8.1 4 2 5 9 9 9 9 Leucine rich repeat LRR_4 PF12799.7 CRK28362.1 - 1e-21 76.6 47.0 0.00072 19.9 1.5 9.9 6 2 4 11 11 11 9 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CRK28362.1 - 0.00084 18.9 24.4 0.15 11.5 2.9 5.5 2 2 4 6 6 6 4 Leucine-rich repeat LRR_6 PF13516.6 CRK28362.1 - 0.0067 16.4 29.3 6.7 7.0 0.0 10.1 12 0 0 12 12 12 3 Leucine Rich repeat LRR_1 PF00560.33 CRK28362.1 - 0.51 11.1 28.5 90 4.2 0.1 10.9 13 2 0 13 13 13 0 Leucine Rich Repeat Cupin_2 PF07883.11 CRK28363.1 - 3.8e-22 77.8 1.5 1.5e-10 40.6 0.0 2.2 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 CRK28363.1 - 9.4e-05 22.3 1.1 0.34 10.8 0.0 2.2 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_3 PF05899.12 CRK28363.1 - 0.00019 21.1 0.0 0.63 9.8 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF861) CENP-C_C PF11699.8 CRK28363.1 - 0.0028 17.8 0.0 0.0056 16.9 0.0 1.5 2 0 0 2 2 2 1 Mif2/CENP-C like EutQ PF06249.12 CRK28363.1 - 0.037 13.8 0.0 2.2 8.0 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation protein EutQ RPE65 PF03055.15 CRK28364.1 - 5.4e-10 39.1 0.0 6.6e-10 38.8 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Colicin_D PF11429.8 CRK28364.1 - 0.073 13.5 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 Colicin D NPP1 PF05630.11 CRK28365.1 - 9.6e-52 176.0 0.1 1.1e-51 175.7 0.1 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) MFS_1 PF07690.16 CRK28366.1 - 1.1e-16 60.7 33.0 4.6e-12 45.5 23.6 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK28366.1 - 0.0053 15.7 0.2 0.0053 15.7 0.2 3.6 3 1 0 3 3 3 1 Sugar (and other) transporter DUF1929 PF09118.11 CRK28367.1 - 3.9e-23 81.6 0.0 8.7e-23 80.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_6 PF13964.6 CRK28367.1 - 1.1e-16 60.5 0.0 0.00032 20.9 0.0 4.2 3 0 0 3 3 3 3 Kelch motif PAN_1 PF00024.26 CRK28367.1 - 4.6e-15 55.3 9.7 1.1e-07 31.6 2.0 2.4 2 0 0 2 2 2 2 PAN domain Kelch_1 PF01344.25 CRK28367.1 - 2.8e-12 46.0 0.1 0.0025 17.3 0.0 3.8 3 0 0 3 3 3 3 Kelch motif Kelch_4 PF13418.6 CRK28367.1 - 7.1e-07 29.1 5.6 0.00034 20.6 0.0 4.9 5 0 0 5 5 5 1 Galactose oxidase, central domain Glyoxal_oxid_N PF07250.11 CRK28367.1 - 2.9e-06 26.7 0.0 0.18 11.0 0.0 3.2 2 1 1 3 3 3 2 Glyoxal oxidase N-terminus Kelch_2 PF07646.15 CRK28367.1 - 0.0002 21.2 0.0 7.6 6.7 0.0 4.8 4 0 0 4 4 4 1 Kelch motif PAN_4 PF14295.6 CRK28367.1 - 0.00028 20.7 13.9 0.0085 16.0 1.7 2.6 2 0 0 2 2 2 2 PAN domain MANEC PF07502.14 CRK28367.1 - 0.0047 17.2 8.3 0.14 12.4 2.1 2.5 2 0 0 2 2 2 2 MANEC domain Kelch_3 PF13415.6 CRK28367.1 - 0.11 12.9 0.2 1.8 8.9 0.1 3.2 3 0 0 3 3 3 0 Galactose oxidase, central domain PAN_3 PF08277.12 CRK28367.1 - 2 8.3 8.3 9.9 6.1 2.2 2.5 2 0 0 2 2 2 0 PAN-like domain TPP_enzyme_N PF02776.18 CRK28368.1 - 4.7e-36 124.0 1.4 1.4e-35 122.5 1.4 1.9 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Fungal_trans PF04082.18 CRK28368.1 - 8.9e-19 67.5 0.1 1.5e-18 66.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain TPP_enzyme_C PF02775.21 CRK28368.1 - 3.1e-14 53.0 0.0 7.9e-14 51.7 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 CRK28368.1 - 1.2e-07 31.5 0.0 2.6e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Zn_clus PF00172.18 CRK28368.1 - 0.023 14.8 12.3 0.038 14.1 12.3 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 CRK28369.1 - 7.3e-39 133.7 26.3 4.3e-38 131.1 27.7 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Vint PF14623.6 CRK28370.1 - 1.5e-64 216.8 0.0 3.6e-64 215.6 0.0 1.7 2 0 0 2 2 2 1 Hint-domain Vwaint PF14624.6 CRK28370.1 - 4.8e-28 97.1 0.0 8.8e-28 96.2 0.0 1.5 1 0 0 1 1 1 1 VWA / Hh protein intein-like VWA PF00092.28 CRK28370.1 - 7.4e-16 58.9 0.0 1.4e-15 58.0 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 CRK28370.1 - 1.2e-11 44.8 0.0 2.7e-09 37.1 0.0 2.9 3 0 0 3 3 3 1 von Willebrand factor type A domain VWA_2 PF13519.6 CRK28370.1 - 1.3e-11 45.1 0.0 3.4e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain Lactamase_B_2 PF12706.7 CRK28370.1 - 0.003 17.1 0.2 0.0064 16.0 0.2 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 CRK28370.1 - 0.008 16.1 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain PDR_CDR PF06422.12 CRK28371.1 - 9.9e-19 67.0 0.3 1.9e-18 66.1 0.3 1.4 1 0 0 1 1 1 1 CDR ABC transporter ABC_tran PF00005.27 CRK28371.1 - 2.4e-17 63.7 0.0 3.4e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_25 PF13481.6 CRK28371.1 - 3.7e-05 23.4 0.1 0.00011 21.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 CRK28371.1 - 3.8e-05 23.7 0.0 5.8e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 CRK28371.1 - 5.4e-05 23.6 0.0 8.9e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 CRK28371.1 - 0.00077 20.0 0.0 0.0015 19.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 CRK28371.1 - 0.0028 17.4 0.1 0.0052 16.5 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 CRK28371.1 - 0.0031 17.4 0.3 0.2 11.4 0.0 2.5 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system cobW PF02492.19 CRK28371.1 - 0.0094 15.5 0.3 0.021 14.4 0.2 1.6 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 CRK28371.1 - 0.012 15.7 0.0 0.026 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CRK28371.1 - 0.016 15.8 0.0 0.035 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CRK28371.1 - 0.046 14.0 0.2 0.084 13.2 0.2 1.5 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 CRK28371.1 - 0.086 13.1 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CRK28371.1 - 0.19 11.4 0.5 0.43 10.3 0.5 1.6 1 1 0 1 1 1 0 AAA domain HEAT_EZ PF13513.6 CRK28372.1 - 3.4e-08 33.8 0.6 0.00041 20.8 0.1 2.1 1 1 1 2 2 2 2 HEAT-like repeat HEAT PF02985.22 CRK28372.1 - 1.1e-07 31.5 0.6 1.5e-05 24.9 0.0 2.7 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.6 CRK28372.1 - 9.3e-07 29.2 0.8 2.9e-06 27.6 0.8 1.8 1 1 0 1 1 1 1 HEAT repeats CLASP_N PF12348.8 CRK28372.1 - 0.00089 18.9 0.1 0.0018 17.9 0.0 1.5 1 1 0 1 1 1 1 CLASP N terminal Cnd1 PF12717.7 CRK28372.1 - 0.0013 18.8 0.1 0.0014 18.7 0.1 1.1 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 CRK28372.1 - 0.0029 17.6 0.5 7.7 6.7 0.0 3.1 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat MMS19_C PF12460.8 CRK28372.1 - 0.0043 16.2 0.2 0.0051 16.0 0.2 1.2 1 0 0 1 1 1 1 RNAPII transcription regulator C-terminal Ipi1_N PF12333.8 CRK28372.1 - 0.0045 17.6 0.0 0.0055 17.3 0.0 1.2 1 0 0 1 1 1 1 Rix1 complex component involved in 60S ribosome maturation UME PF08064.13 CRK28372.1 - 0.006 16.5 0.0 0.0067 16.3 0.0 1.1 1 0 0 1 1 1 1 UME (NUC010) domain ParcG PF10274.9 CRK28372.1 - 0.013 15.7 0.0 0.014 15.6 0.0 1.1 1 0 0 1 1 1 0 Parkin co-regulated protein Vac14_Fab1_bd PF12755.7 CRK28372.1 - 0.013 16.1 0.0 0.016 15.8 0.0 1.2 1 0 0 1 1 1 0 Vacuolar 14 Fab1-binding region Cohesin_HEAT PF12765.7 CRK28372.1 - 0.02 15.2 0.2 0.055 13.8 0.2 1.8 1 0 0 1 1 1 0 HEAT repeat associated with sister chromatid cohesion FANCI_S2 PF14676.6 CRK28372.1 - 0.041 14.2 0.0 0.085 13.2 0.0 1.5 1 1 1 2 2 2 0 FANCI solenoid 2 SepZ PF06066.11 CRK28374.1 - 0.19 12.0 3.3 11 6.3 0.2 2.5 2 0 0 2 2 2 0 SepZ zf-CCHC PF00098.23 CRK28375.1 - 8.8e-23 79.3 34.8 2.7e-07 30.4 2.1 4.3 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_3 PF13917.6 CRK28375.1 - 3.8e-06 26.7 26.9 0.059 13.4 0.8 4.1 1 1 3 4 4 4 4 Zinc knuckle zf-CCHC_6 PF15288.6 CRK28375.1 - 2.8e-05 23.9 24.8 0.0074 16.1 1.2 4.3 3 1 1 4 4 4 3 Zinc knuckle zf-CCHC_4 PF14392.6 CRK28375.1 - 0.043 13.5 21.5 0.67 9.7 0.9 4.1 4 0 0 4 4 4 0 Zinc knuckle zf-CCHC_2 PF13696.6 CRK28375.1 - 0.049 13.5 28.8 0.17 11.7 2.6 4.6 4 0 0 4 4 4 0 Zinc knuckle TRAF6_Z2 PF18048.1 CRK28375.1 - 2.3 8.4 9.5 8.8 6.5 0.4 3.5 3 0 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 zinc_ribbon_4 PF13717.6 CRK28375.1 - 8.3 6.4 17.9 16 5.5 0.7 3.6 3 1 0 3 3 3 0 zinc-ribbon domain zf-CCHC PF00098.23 CRK28376.1 - 6e-13 48.2 22.1 1.5e-07 31.2 3.6 3.3 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_2 PF13696.6 CRK28376.1 - 2e-06 27.5 17.7 0.0045 16.8 1.4 3.3 3 0 0 3 3 3 3 Zinc knuckle zf-C2H2_10 PF16588.5 CRK28376.1 - 5.5e-05 22.8 9.3 0.0028 17.3 0.7 2.4 2 0 0 2 2 2 2 C2H2 zinc-finger zf-CCHC_3 PF13917.6 CRK28376.1 - 0.032 14.2 0.2 0.032 14.2 0.2 2.9 1 1 2 3 3 3 0 Zinc knuckle zf-CCHC_4 PF14392.6 CRK28376.1 - 5.7 6.8 10.8 0.82 9.4 0.4 2.7 3 0 0 3 3 3 0 Zinc knuckle Aldo_ket_red PF00248.21 CRK28377.1 - 1.6e-50 172.0 0.0 2.3e-50 171.5 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_20 PF00728.22 CRK28378.1 - 3.5e-25 89.1 1.7 8.9e-25 87.8 1.7 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain F-box-like PF12937.7 CRK28378.1 - 7.6e-09 35.3 0.1 3.6e-08 33.2 0.3 2.1 2 0 0 2 2 2 1 F-box-like Glyco_hydro_20b PF02838.15 CRK28378.1 - 2.3e-07 31.6 0.0 4.8e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 F-box PF00646.33 CRK28378.1 - 3.1e-05 23.7 0.1 9.8e-05 22.1 0.1 1.8 1 0 0 1 1 1 1 F-box domain TPR_1 PF00515.28 CRK28378.1 - 0.00081 19.1 0.6 3.1 7.8 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 CRK28378.1 - 0.018 15.1 3.8 21 5.5 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3760 PF12586.8 CRK28378.1 - 0.025 14.8 0.2 0.084 13.1 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3760) TPR_14 PF13428.6 CRK28378.1 - 0.13 13.1 2.4 0.45 11.5 0.5 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat SEC-C PF02810.15 CRK28378.1 - 0.94 9.5 6.2 2.1 8.3 6.2 1.6 1 0 0 1 1 1 0 SEC-C motif Pkinase PF00069.25 CRK28381.1 - 0.014 14.8 0.0 0.018 14.4 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain polyprenyl_synt PF00348.17 CRK28382.1 - 2.3e-45 154.7 0.0 3.7e-45 154.0 0.0 1.3 1 0 0 1 1 1 1 Polyprenyl synthetase Pkinase PF00069.25 CRK28382.1 - 2.8e-35 122.0 0.0 7.3e-17 61.6 0.0 3.2 2 1 1 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CRK28382.1 - 1.8e-09 37.3 0.5 0.0022 17.3 0.1 3.3 2 1 1 3 3 3 3 Protein tyrosine kinase DUF3618 PF12277.8 CRK28382.1 - 0.013 15.7 2.4 5 7.5 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) PglD_N PF17836.1 CRK28382.1 - 0.28 11.9 0.6 5.8 7.6 0.1 2.4 2 0 0 2 2 2 0 PglD N-terminal domain Pex24p PF06398.11 CRK28383.1 - 6.3e-64 216.2 7.5 4.2e-62 210.2 0.0 2.2 1 1 1 2 2 2 2 Integral peroxisomal membrane peroxin DUF639 PF04842.12 CRK28383.1 - 0.032 13.6 0.2 0.068 12.6 0.2 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) DUF3292 PF11696.8 CRK28383.1 - 0.18 10.1 11.8 0.066 11.6 0.3 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3292) Spt20 PF12090.8 CRK28383.1 - 0.81 9.3 7.1 1.2 8.7 7.1 1.1 1 0 0 1 1 1 0 Spt20 family Pex24p PF06398.11 CRK28384.1 - 4.8e-55 187.0 0.1 6.1e-55 186.7 0.1 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin HCV_NS4a PF01006.20 CRK28384.1 - 5.4 6.9 4.8 11 5.9 0.4 2.5 2 0 0 2 2 2 0 Hepatitis C virus non-structural protein NS4a CDC14 PF08045.11 CRK28385.1 - 1.4e-127 424.6 0.0 1.8e-127 424.3 0.0 1.1 1 0 0 1 1 1 1 Cell division control protein 14, SIN component SKG6 PF08693.10 CRK28387.1 - 1.7 8.1 4.1 2.9 7.4 4.1 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain APH PF01636.23 CRK28388.1 - 5.6e-09 36.3 6.3 4.5e-08 33.3 5.1 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 CRK28388.1 - 7.2e-08 32.0 0.0 0.00084 18.7 0.0 3.2 3 1 0 3 3 3 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 CRK28388.1 - 1.1e-06 28.2 0.0 7.2e-06 25.6 0.0 2.2 2 1 1 3 3 3 1 Protein kinase domain Pkinase_fungal PF17667.1 CRK28388.1 - 0.00036 19.4 0.0 0.00055 18.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase eIF3_subunit PF08597.10 CRK28388.1 - 0.0012 18.8 4.8 0.0016 18.4 4.8 1.1 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Med15 PF09606.10 CRK28388.1 - 0.0022 16.8 8.4 0.0026 16.5 8.4 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal DUF2722 PF10846.8 CRK28388.1 - 0.0044 16.0 10.0 0.0055 15.7 10.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 CRK28388.1 - 0.0065 16.5 9.8 0.0081 16.2 9.8 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit EcKinase PF02958.20 CRK28388.1 - 0.034 13.5 0.0 0.45 9.8 0.0 2.0 2 0 0 2 2 2 0 Ecdysteroid kinase Spt20 PF12090.8 CRK28388.1 - 0.04 13.5 17.6 0.056 13.1 17.6 1.1 1 0 0 1 1 1 0 Spt20 family RIO1 PF01163.22 CRK28388.1 - 0.052 13.1 0.3 1.3 8.6 0.0 2.7 2 1 1 3 3 3 0 RIO1 family Tau95_N PF17682.1 CRK28388.1 - 0.056 13.6 2.6 0.19 11.9 2.6 1.8 1 1 0 1 1 1 0 Tau95 Triple barrel domain Pkinase_Tyr PF07714.17 CRK28388.1 - 0.071 12.4 0.0 0.14 11.4 0.0 1.5 1 1 0 1 1 1 0 Protein tyrosine kinase Choline_kinase PF01633.20 CRK28388.1 - 0.12 11.9 0.0 0.27 10.8 0.0 1.4 1 1 0 1 1 1 0 Choline/ethanolamine kinase DUF4638 PF15472.6 CRK28388.1 - 0.15 11.7 4.2 0.25 11.0 4.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) DUF775 PF05603.12 CRK28388.1 - 0.22 11.0 3.6 0.31 10.6 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) DUF4834 PF16118.5 CRK28388.1 - 0.46 11.5 6.5 0.74 10.8 6.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Usp PF00582.26 CRK28388.1 - 0.73 10.3 4.8 1.4 9.4 4.8 1.4 1 0 0 1 1 1 0 Universal stress protein family Presenilin PF01080.17 CRK28388.1 - 0.76 8.5 4.3 1 8.0 4.3 1.1 1 0 0 1 1 1 0 Presenilin EIIBC-GUT_N PF03612.14 CRK28388.1 - 1.2 8.9 4.8 2.1 8.1 4.8 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus SprA-related PF12118.8 CRK28388.1 - 3.2 6.8 16.2 4.7 6.3 16.2 1.1 1 0 0 1 1 1 0 SprA-related family Androgen_recep PF02166.16 CRK28388.1 - 3.5 6.4 28.4 0.059 12.2 20.5 1.8 2 0 0 2 2 2 0 Androgen receptor Radial_spoke_3 PF06098.11 CRK28388.1 - 6 6.1 15.4 8.5 5.5 15.4 1.1 1 0 0 1 1 1 0 Radial spoke protein 3 Med3 PF11593.8 CRK28388.1 - 8.4 5.5 14.7 13 4.9 14.7 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Acyl_transf_3 PF01757.22 CRK28390.1 - 1.6e-43 149.1 32.4 2.1e-43 148.7 32.4 1.1 1 0 0 1 1 1 1 Acyltransferase family Ribosomal_L7Ae PF01248.26 CRK28392.1 - 2.3e-24 84.9 0.0 2.6e-24 84.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SUR7 PF06687.12 CRK28396.1 - 2.5e-18 66.5 13.8 3.2e-18 66.1 13.8 1.1 1 0 0 1 1 1 1 SUR7/PalI family TMEM132D_C PF15706.5 CRK28396.1 - 8.3 6.3 8.8 3.6 7.4 0.2 2.6 1 1 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term GST_N_4 PF17172.4 CRK28400.1 - 1.3e-16 61.2 0.0 2.3e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 CRK28400.1 - 5.6e-08 33.1 0.1 6.1e-07 29.8 0.0 2.5 2 1 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 CRK28400.1 - 1.3e-07 31.3 0.0 4.3e-07 29.6 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain IDO PF01231.18 CRK28402.1 - 1.7e-22 79.8 0.0 2.2e-14 53.1 0.0 2.2 1 1 1 2 2 2 2 Indoleamine 2,3-dioxygenase ApbA_C PF08546.11 CRK28402.1 - 0.15 12.2 0.0 0.65 10.2 0.0 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA C terminal INO80_Ies4 PF08193.11 CRK28405.1 - 7.7e-76 255.3 26.1 7.7e-76 255.3 26.1 1.8 1 1 0 1 1 1 1 INO80 complex subunit Ies4 CLTH PF10607.9 CRK28407.1 - 5.5e-30 104.2 0.0 9.3e-30 103.5 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 CRK28407.1 - 5.5e-25 87.8 0.1 1.1e-24 86.9 0.1 1.5 1 0 0 1 1 1 1 SPRY domain LisH PF08513.11 CRK28407.1 - 4.2e-06 26.5 0.2 1.2e-05 25.1 0.0 1.9 2 0 0 2 2 2 1 LisH MFS_1 PF07690.16 CRK28408.1 - 1.3e-45 155.8 33.8 1.3e-45 155.8 33.8 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK28408.1 - 1.8e-09 37.0 10.9 1.8e-09 37.0 10.9 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 CRK28408.1 - 1.1e-05 25.0 7.3 1.1e-05 25.0 7.3 3.1 1 1 2 3 3 3 2 Uncharacterised MFS-type transporter YbfB MFS_3 PF05977.13 CRK28408.1 - 3.8 5.8 17.5 0.027 12.9 9.4 1.4 2 0 0 2 2 2 0 Transmembrane secretion effector Aldedh PF00171.22 CRK28410.1 - 7.9e-06 24.6 8.1 0.0046 15.5 5.8 3.2 2 1 0 2 2 2 2 Aldehyde dehydrogenase family Chitin_synth_1 PF01644.17 CRK28414.1 - 7.3e-69 230.9 0.2 8.3e-56 188.5 0.0 3.3 3 1 0 3 3 3 2 Chitin synthase Chitin_synth_1N PF08407.11 CRK28414.1 - 1.2e-54 182.1 0.2 7.9e-26 89.8 0.0 2.6 2 0 0 2 2 2 2 Chitin synthase N-terminal IlvN PF07991.12 CRK28414.1 - 3.4e-44 150.3 0.5 7.4e-44 149.2 0.0 1.8 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 CRK28414.1 - 1e-39 136.1 0.0 1e-39 136.1 0.0 2.4 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain UQ_con PF00179.26 CRK28414.1 - 1.6e-36 125.0 0.0 3.5e-36 123.9 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Chitin_synth_2 PF03142.15 CRK28414.1 - 6.3e-27 94.4 0.6 2.1e-21 76.1 0.0 3.2 3 0 0 3 3 3 2 Chitin synthase Fungal_TACC PF12709.7 CRK28414.1 - 3.1e-09 37.2 0.4 3.1e-09 37.2 0.4 3.7 4 0 0 4 4 3 2 Fungal Transforming acidic coiled-coil (TACC) proteins Glyco_trans_2_3 PF13632.6 CRK28414.1 - 2.1e-08 34.3 0.1 4.7e-08 33.2 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase family group 2 ADK_lid PF05191.14 CRK28414.1 - 0.037 14.0 0.0 26 4.9 0.0 3.3 3 0 0 3 3 3 0 Adenylate kinase, active site lid F420_oxidored PF03807.17 CRK28414.1 - 0.16 12.6 0.0 0.79 10.3 0.0 2.3 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Peripla_BP_7 PF18610.1 CRK28414.1 - 0.17 12.1 0.2 26 5.1 0.0 2.6 2 0 0 2 2 2 0 Periplasmic binding protein domain DUF4778 PF16008.5 CRK28414.1 - 6.1 6.8 16.5 20 5.1 16.4 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4778) Opy2 PF09463.10 CRK28420.1 - 1.9e-06 28.1 6.6 3e-06 27.4 6.6 1.3 1 0 0 1 1 1 1 Opy2 protein Mid2 PF04478.12 CRK28420.1 - 0.044 13.6 0.1 0.075 12.9 0.1 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Syndecan PF01034.20 CRK28420.1 - 0.091 12.7 0.1 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain Opy2 PF09463.10 CRK28422.1 - 1.5e-07 31.6 15.5 2.3e-07 31.0 15.5 1.3 1 0 0 1 1 1 1 Opy2 protein Syndecan PF01034.20 CRK28422.1 - 0.063 13.2 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain Ras PF00071.22 CRK28424.1 - 3.9e-33 114.4 0.0 1.1e-32 112.9 0.0 1.6 1 1 0 1 1 1 1 Ras family Roc PF08477.13 CRK28424.1 - 5.8e-07 29.8 0.0 1.6e-05 25.1 0.0 2.3 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Abhydrolase_4 PF08386.10 CRK28424.1 - 0.024 14.8 0.0 0.039 14.1 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Ras PF00071.22 CRK28426.1 - 1.8e-51 174.0 0.0 4.3e-51 172.7 0.0 1.6 1 1 0 1 1 1 1 Ras family Roc PF08477.13 CRK28426.1 - 3.3e-18 66.0 0.0 6.4e-17 61.9 0.0 2.2 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CRK28426.1 - 0.00028 20.4 0.0 0.0011 18.4 0.0 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CRK28426.1 - 0.0088 16.0 0.0 2.6 7.9 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase Abhydrolase_4 PF08386.10 CRK28426.1 - 0.028 14.5 0.0 0.067 13.3 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein FeoB_N PF02421.18 CRK28426.1 - 0.034 13.7 0.2 0.53 9.8 0.0 2.3 2 1 1 3 3 3 0 Ferrous iron transport protein B SRPRB PF09439.10 CRK28426.1 - 0.043 13.2 0.0 2 7.8 0.0 2.2 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 CRK28426.1 - 0.056 13.8 0.0 0.078 13.4 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 CRK28426.1 - 0.09 12.3 0.2 0.35 10.4 0.1 1.8 1 1 1 2 2 2 0 AAA domain Septin PF00735.18 CRK28426.1 - 0.098 11.9 0.0 0.23 10.7 0.0 1.6 2 0 0 2 2 2 0 Septin HAD_2 PF13419.6 CRK28428.1 - 1.6e-05 25.1 0.0 2.3e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CRK28428.1 - 1.7e-05 25.2 0.0 3.2e-05 24.3 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CRK28428.1 - 8.9e-05 22.5 0.0 0.00019 21.5 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Mcp5_PH PF12814.7 CRK28433.1 - 1.5e-47 160.7 0.0 4.3e-47 159.2 0.0 1.9 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology Fez1 PF06818.15 CRK28433.1 - 6.7e-07 30.0 26.6 0.005 17.3 8.9 2.9 2 0 0 2 2 2 2 Fez1 HYLS1_C PF15311.6 CRK28433.1 - 0.0031 18.2 0.6 2.2 9.1 0.0 3.1 2 0 0 2 2 2 1 Hydrolethalus syndrome protein 1 C-terminus PSRP-3_Ycf65 PF04839.13 CRK28433.1 - 0.069 13.4 4.0 7.2 6.9 0.3 2.5 2 0 0 2 2 2 0 Plastid and cyanobacterial ribosomal protein (PSRP-3 / Ycf65) PH_12 PF16457.5 CRK28433.1 - 0.084 13.4 0.0 0.79 10.3 0.0 2.8 1 1 0 1 1 1 0 Pleckstrin homology domain Sipho_Gp157 PF05565.11 CRK28433.1 - 0.37 10.8 9.7 3.1 7.8 1.4 2.6 2 0 0 2 2 2 0 Siphovirus Gp157 Melibiase_C PF17801.1 CRK28433.1 - 0.46 10.6 2.8 24 5.1 0.2 2.5 2 0 0 2 2 2 0 Alpha galactosidase C-terminal beta sandwich domain TPR_MLP1_2 PF07926.12 CRK28433.1 - 1.4 9.0 40.5 4.6 7.3 13.9 4.1 2 2 2 4 4 4 0 TPR/MLP1/MLP2-like protein Cep57_CLD_2 PF14197.6 CRK28433.1 - 5.9 7.0 21.8 32 4.7 1.0 6.1 4 2 2 6 6 6 0 Centrosome localisation domain of PPC89 OTU PF02338.19 CRK28435.1 - 4.3e-23 82.2 0.0 9.7e-20 71.4 0.0 2.5 2 0 0 2 2 2 2 OTU-like cysteine protease PseudoU_synth_2 PF00849.22 CRK28435.1 - 0.00045 20.3 0.2 0.67 10.0 0.0 2.7 2 1 0 3 3 3 2 RNA pseudouridylate synthase Importin_rep_4 PF18808.1 CRK28435.1 - 8.6 6.7 14.4 10 6.5 3.1 2.7 2 0 0 2 2 2 0 Importin repeat TPMT PF05724.11 CRK28437.1 - 5.2e-29 101.5 0.0 8.4e-29 100.8 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_23 PF13489.6 CRK28437.1 - 1.3e-07 31.6 0.0 1.9e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK28437.1 - 8.1e-06 26.5 0.0 0.00048 20.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK28437.1 - 1.2e-05 25.1 0.0 0.023 14.5 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 CRK28437.1 - 6.1e-05 23.6 0.0 0.001 19.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 CRK28437.1 - 0.0083 15.6 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB N2227 PF07942.12 CRK28437.1 - 0.12 11.6 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 N2227-like protein PALP PF00291.25 CRK28439.1 - 6.4e-12 45.5 0.1 2.3e-11 43.7 0.1 1.8 1 1 1 2 2 2 1 Pyridoxal-phosphate dependent enzyme Amidohydro_3 PF07969.11 CRK28441.1 - 1.8e-15 57.4 0.0 2.7e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family HAD_2 PF13419.6 CRK28441.1 - 3.5e-05 24.0 0.0 5e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CRK28441.1 - 0.00023 21.2 0.0 0.00045 20.2 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 CRK28441.1 - 0.0013 19.0 0.0 0.0052 17.1 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Amidohydro_1 PF01979.20 CRK28441.1 - 0.0021 17.4 0.0 0.0034 16.8 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family TPMT PF05724.11 CRK28447.1 - 1.8e-29 102.9 0.0 3e-29 102.3 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_23 PF13489.6 CRK28447.1 - 2.8e-08 33.8 0.0 4.1e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK28447.1 - 4.2e-06 26.6 0.0 0.0079 16.0 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 CRK28447.1 - 5.1e-06 27.1 0.0 0.00031 21.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CRK28447.1 - 2.5e-05 24.8 0.0 0.00043 20.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK28447.1 - 0.00011 22.9 0.0 0.00033 21.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 CRK28447.1 - 0.0081 15.6 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB N2227 PF07942.12 CRK28447.1 - 0.22 10.7 0.0 0.33 10.1 0.0 1.2 1 0 0 1 1 1 0 N2227-like protein PALP PF00291.25 CRK28449.1 - 1.7e-61 208.2 0.6 2.1e-61 207.9 0.6 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Amidohydro_3 PF07969.11 CRK28450.1 - 5.1e-73 247.2 0.1 2.9e-60 205.1 0.1 2.1 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 CRK28450.1 - 0.00017 21.0 0.4 0.0097 15.3 0.0 3.2 3 1 0 3 3 3 1 Amidohydrolase family Fels1 PF05666.11 CRK28450.1 - 0.17 11.6 0.1 30 4.3 0.0 2.5 2 0 0 2 2 2 0 Fels-1 Prophage Protein-like Rhomboid PF01694.22 CRK28450.1 - 0.24 11.4 0.8 17 5.4 0.0 2.3 2 0 0 2 2 2 0 Rhomboid family Atg14 PF10186.9 CRK28454.1 - 0.09 11.8 0.1 0.16 11.0 0.1 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ALAD PF00490.21 CRK28457.1 - 1.1e-120 402.6 0.0 1.4e-120 402.3 0.0 1.1 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Trimer_CC PF08954.11 CRK28458.1 - 0.033 13.7 0.1 0.14 11.7 0.1 2.1 1 0 0 1 1 1 0 Trimerisation motif TRPM_tetra PF16519.5 CRK28458.1 - 0.91 9.7 3.1 50 4.1 0.0 3.1 2 1 1 3 3 3 0 Tetramerisation domain of TRPM Vps62 PF06101.11 CRK28460.1 - 2.7e-10 39.2 5.0 3.7e-10 38.7 0.5 2.7 3 0 0 3 3 3 1 Vacuolar protein sorting-associated protein 62 RNA_pol_N PF01194.17 CRK28460.1 - 0.12 12.7 0.0 38 4.7 0.0 2.9 3 0 0 3 3 3 0 RNA polymerases N / 8 kDa subunit Chrome_Resist PF09828.9 CRK28460.1 - 2.7 8.4 12.2 8.9 6.8 2.4 2.3 2 0 0 2 2 2 0 Chromate resistance exported protein DUF4229 PF14012.6 CRK28460.1 - 6.2 7.0 5.9 28 4.9 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) eIF-5_eIF-2B PF01873.17 CRK28463.1 - 9.1e-42 141.6 0.6 1.5e-41 140.9 0.6 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 zinc_ribbon_6 PF14599.6 CRK28463.1 - 0.079 13.0 0.7 7.8 6.6 0.1 2.5 2 0 0 2 2 2 0 Zinc-ribbon Spike_NTD PF16451.5 CRK28463.1 - 0.12 11.7 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 Spike glycoprotein N-terminal domain Lar_restr_allev PF14354.6 CRK28463.1 - 0.17 12.3 1.2 2.6 8.5 1.2 2.6 1 1 0 1 1 1 0 Restriction alleviation protein Lar TF_Zn_Ribbon PF08271.12 CRK28463.1 - 0.93 9.1 3.8 3.1 7.4 3.8 1.8 1 1 0 1 1 1 0 TFIIB zinc-binding Arc_trans_TRASH PF08394.10 CRK28463.1 - 2.3 8.6 8.6 1.8 8.9 0.6 2.5 1 1 1 2 2 2 0 Archaeal TRASH domain zf-HYPF PF07503.12 CRK28463.1 - 4.4 7.2 7.3 2.8 7.8 4.5 2.2 2 1 1 3 3 3 0 HypF finger DUF1654 PF07867.11 CRK28465.1 - 0.18 11.6 1.9 0.25 11.1 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1654) DUF1712 PF08217.11 CRK28467.1 - 2.2e-11 43.0 0.0 5.9e-09 35.0 0.0 2.6 2 1 0 2 2 2 2 Fungal domain of unknown function (DUF1712) Ank_2 PF12796.7 CRK28470.1 - 4e-43 145.9 0.0 2.6e-13 50.4 0.0 7.5 1 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CRK28470.1 - 9.5e-37 124.9 0.1 2.5e-07 31.1 0.0 7.6 4 2 2 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 CRK28470.1 - 5.3e-33 112.7 0.3 3.3e-10 40.0 0.0 8.0 5 2 3 8 8 8 6 Ankyrin repeats (many copies) Ank PF00023.30 CRK28470.1 - 3.7e-30 103.0 0.1 0.038 14.5 0.0 11.3 11 0 0 11 11 11 7 Ankyrin repeat Ank_3 PF13606.6 CRK28470.1 - 2.2e-28 95.1 0.2 0.0021 18.4 0.0 11.4 12 0 0 12 12 12 5 Ankyrin repeat Shigella_OspC PF06128.11 CRK28470.1 - 0.19 11.5 0.0 15 5.2 0.0 2.8 3 0 0 3 3 3 0 Shigella flexneri OspC protein ICL PF00463.21 CRK28472.1 - 6.8e-284 942.2 0.1 8.3e-284 941.9 0.1 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 CRK28472.1 - 2.7e-11 43.4 1.1 8.3e-11 41.8 0.0 2.2 2 1 0 2 2 2 1 Phosphoenolpyruvate phosphomutase DUF1279 PF06916.13 CRK28475.1 - 2.2e-24 85.8 0.2 6.1e-24 84.4 0.2 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) OCC1 PF15506.6 CRK28477.1 - 8.4 6.6 8.3 3.5 7.8 4.2 2.2 2 1 1 3 3 3 0 OCC1 family PNGaseA PF12222.8 CRK28479.1 - 8.1e-152 506.0 0.1 1.2e-151 505.5 0.1 1.2 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A Pkinase PF00069.25 CRK28481.1 - 9.4e-70 235.0 0.0 1.3e-69 234.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK28481.1 - 2.4e-33 115.5 0.0 3.9e-33 114.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 CRK28481.1 - 2.9e-19 69.6 0.8 4.1e-11 43.4 0.2 2.9 2 1 0 2 2 2 2 Adenylate sensor of SNF1-like protein kinase UBA_2 PF08587.11 CRK28481.1 - 3.1e-16 59.2 0.4 6.8e-16 58.1 0.4 1.6 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.6 CRK28481.1 - 3.7e-05 23.2 0.0 6.5e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CRK28481.1 - 0.00059 18.9 1.2 0.00075 18.5 0.3 1.6 2 0 0 2 2 2 1 Haspin like kinase domain MaoC_dehydrat_N PF13452.6 CRK28481.1 - 0.01 16.0 0.3 1.9 8.6 0.0 2.6 2 0 0 2 2 2 0 N-terminal half of MaoC dehydratase RIO1 PF01163.22 CRK28481.1 - 0.018 14.6 0.2 0.055 13.1 0.1 1.7 1 1 0 1 1 1 0 RIO1 family YukC PF10140.9 CRK28481.1 - 0.02 13.7 0.0 0.032 13.1 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC APH PF01636.23 CRK28481.1 - 0.11 12.4 0.3 0.3 11.0 0.2 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 CRK28481.1 - 0.15 11.4 0.3 0.3 10.4 0.3 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DNA_pol_E_B PF04042.16 CRK28485.1 - 4.2e-65 219.0 0.0 6.1e-65 218.5 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B FUSC_2 PF13515.6 CRK28487.1 - 1e-23 83.8 6.8 1e-23 83.8 6.8 2.5 2 0 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.8 CRK28487.1 - 6.7e-06 25.2 11.2 0.0002 20.4 6.1 3.7 4 0 0 4 4 4 1 Aluminium activated malate transporter ArAE_2 PF10334.9 CRK28487.1 - 0.036 13.9 0.0 0.11 12.3 0.0 1.8 2 0 0 2 2 2 0 Aromatic acid exporter family member 2 FUSC-like PF12805.7 CRK28487.1 - 0.096 11.7 3.6 0.17 11.0 0.7 2.5 3 0 0 3 3 3 0 FUSC-like inner membrane protein yccS HAD_2 PF13419.6 CRK28488.1 - 3.8e-14 53.2 0.0 1.1e-13 51.7 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CRK28488.1 - 3.6e-10 40.5 0.0 1.2e-06 29.0 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CRK28488.1 - 1.4e-05 25.1 0.8 2.2e-05 24.5 0.2 1.6 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.7 CRK28488.1 - 4.6e-05 23.9 0.1 0.00022 21.7 0.1 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 CRK28488.1 - 0.029 14.0 0.1 1.8 8.1 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase Pkinase PF00069.25 CRK28490.1 - 2.4e-65 220.5 0.0 3.2e-65 220.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK28490.1 - 2.1e-39 135.4 0.0 2.7e-39 135.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CRK28490.1 - 9.9e-05 21.3 0.0 0.00016 20.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CRK28490.1 - 0.00057 19.3 0.0 0.0011 18.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CRK28490.1 - 0.041 12.8 0.0 0.055 12.4 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 CRK28490.1 - 0.1 11.7 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 SH2_2 PF14633.6 CRK28492.1 - 1.3e-81 273.1 0.0 3.1e-81 271.9 0.0 1.7 1 0 0 1 1 1 1 SH2 domain HTH_44 PF14641.6 CRK28492.1 - 4.1e-39 133.6 0.2 1.1e-38 132.2 0.2 1.7 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 HHH_7 PF14635.6 CRK28492.1 - 8.3e-31 106.4 0.0 1.9e-30 105.3 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 CRK28492.1 - 5.3e-28 97.7 0.0 2.6e-27 95.5 0.0 2.3 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.6 CRK28492.1 - 1.9e-18 66.8 31.6 1.9e-18 66.8 31.6 6.9 4 1 4 8 8 8 1 Acidic N-terminal SPT6 HHH_9 PF17674.1 CRK28492.1 - 1.2e-05 26.1 1.8 1.2e-05 26.1 1.8 4.2 3 1 0 3 3 3 1 HHH domain SH2 PF00017.24 CRK28492.1 - 2.2e-05 24.5 0.0 7.3e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 SH2 domain Tex_N PF09371.10 CRK28492.1 - 0.00036 20.3 0.1 0.22 11.2 0.0 2.9 2 0 0 2 2 2 2 Tex-like protein N-terminal domain S1 PF00575.23 CRK28492.1 - 0.0012 19.2 0.9 0.0024 18.2 0.9 1.6 1 0 0 1 1 1 1 S1 RNA binding domain HHH_3 PF12836.7 CRK28492.1 - 0.0018 18.5 0.0 0.0059 16.8 0.0 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix motif RRP7 PF12923.7 CRK28494.1 - 3.5e-24 85.2 12.7 3.5e-24 85.2 12.7 3.0 4 0 0 4 4 4 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain MOSC PF03473.17 CRK28494.1 - 6.6e-24 84.4 0.0 2.4e-23 82.6 0.0 1.9 2 0 0 2 2 2 1 MOSC domain RRM_Rrp7 PF17799.1 CRK28494.1 - 1e-13 51.4 0.0 2.1e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Rrp7 RRM-like N-terminal domain 3-alpha PF03475.14 CRK28494.1 - 3e-05 23.8 0.2 9.4e-05 22.2 0.2 1.9 1 0 0 1 1 1 1 3-alpha domain NAD_binding_1 PF00175.21 CRK28494.1 - 6.1e-05 23.6 2.6 0.0022 18.6 0.0 3.7 3 1 0 3 3 3 1 Oxidoreductase NAD-binding domain SH3_1 PF00018.28 CRK28496.1 - 2.9e-16 58.8 0.1 4.3e-16 58.2 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CRK28496.1 - 1e-13 50.9 0.1 1.6e-13 50.3 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CRK28496.1 - 5.8e-10 38.7 0.0 9.1e-10 38.1 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain BAR PF03114.18 CRK28498.1 - 7.2e-47 160.0 5.9 8.4e-47 159.8 5.9 1.0 1 0 0 1 1 1 1 BAR domain CT_C_D PF02682.16 CRK28498.1 - 0.15 11.8 0.5 0.3 10.8 0.2 1.6 2 0 0 2 2 2 0 Carboxyltransferase domain, subdomain C and D TMPIT PF07851.13 CRK28498.1 - 0.4 9.9 4.2 0.91 8.7 0.1 2.0 1 1 1 2 2 2 0 TMPIT-like protein Ribosomal_S20p PF01649.18 CRK28498.1 - 1.3 9.7 6.6 0.84 10.3 3.1 2.0 2 0 0 2 2 2 0 Ribosomal protein S20 BRE1 PF08647.11 CRK28498.1 - 1.9 8.6 8.8 6.3 7.0 0.4 2.2 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Aminotran_5 PF00266.19 CRK28500.1 - 1.3e-94 317.3 0.0 1.5e-94 317.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 CRK28500.1 - 9.4e-08 31.7 0.0 5.1e-07 29.3 0.1 1.9 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 CRK28500.1 - 2.3e-07 30.4 0.2 3.6e-07 29.7 0.2 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 CRK28500.1 - 0.00078 18.1 0.0 0.0012 17.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Pyridoxal_deC PF00282.19 CRK28500.1 - 0.016 14.0 0.0 0.025 13.3 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain CMD PF02627.20 CRK28502.1 - 5.1e-07 29.6 0.0 9.1e-06 25.6 0.0 2.2 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family BRCA2 PF00634.18 CRK28502.1 - 0.08 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 BRCA2 repeat PRMT5_C PF17286.2 CRK28502.1 - 0.24 11.2 0.0 0.25 11.2 0.0 1.1 1 0 0 1 1 1 0 PRMT5 oligomerisation domain CMD PF02627.20 CRK28505.1 - 2.8e-07 30.5 0.1 1.1e-05 25.4 0.0 2.3 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family BRCA2 PF00634.18 CRK28505.1 - 0.021 14.5 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 BRCA2 repeat PRMT5_C PF17286.2 CRK28505.1 - 0.23 11.3 0.0 0.25 11.2 0.0 1.1 1 0 0 1 1 1 0 PRMT5 oligomerisation domain FACT-Spt16_Nlob PF14826.6 CRK28506.1 - 6.6e-47 159.3 0.1 1.6e-46 158.1 0.1 1.6 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 CRK28506.1 - 1.4e-27 96.8 0.0 2.4e-27 96.0 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 CRK28506.1 - 1.6e-15 57.3 0.7 5.5e-15 55.6 0.1 2.2 2 0 0 2 2 2 1 Histone chaperone Rttp106-like SPT16 PF08644.11 CRK28506.1 - 8.2e-14 52.0 0.0 5.7e-13 49.3 0.0 2.5 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) bZIP_1 PF00170.21 CRK28509.1 - 0.00011 22.3 5.7 0.00011 22.3 5.7 1.7 2 0 0 2 2 2 1 bZIP transcription factor TipAS PF07739.13 CRK28509.1 - 0.023 15.3 1.4 0.039 14.5 1.4 1.4 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain Gastrin PF00918.17 CRK28509.1 - 0.18 12.8 4.4 0.41 11.6 4.4 1.6 1 0 0 1 1 1 0 Gastrin/cholecystokinin family PKcGMP_CC PF16808.5 CRK28509.1 - 0.18 11.7 3.2 0.32 10.9 3.2 1.3 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase bZIP_2 PF07716.15 CRK28509.1 - 2.1 8.5 14.3 0.057 13.5 7.7 1.7 2 0 0 2 2 2 0 Basic region leucine zipper bZIP_Maf PF03131.17 CRK28509.1 - 6 7.5 14.2 0.45 11.1 8.5 2.0 2 0 0 2 2 2 0 bZIP Maf transcription factor Cyt-b5 PF00173.28 CRK28511.1 - 5.7e-09 36.0 0.1 9.4e-09 35.3 0.1 1.4 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain zf-C2H2 PF00096.26 CRK28513.1 - 0.00018 21.7 48.6 0.017 15.5 1.4 8.0 7 0 0 7 7 7 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CRK28513.1 - 2.7 9.1 51.8 0.18 12.7 1.0 8.0 8 0 0 8 8 8 0 C2H2-type zinc finger zf-C2H2 PF00096.26 CRK28517.1 - 0.0039 17.6 1.1 14 6.4 0.1 3.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 CRK28517.1 - 0.0045 17.2 0.1 0.53 10.6 0.0 3.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 CRK28517.1 - 0.0053 17.5 2.0 0.34 11.9 0.1 3.6 3 0 0 3 3 3 1 C2H2-type zinc finger zf-met PF12874.7 CRK28517.1 - 0.024 15.0 0.1 0.69 10.4 0.1 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Kelch_3 PF13415.6 CRK28520.1 - 3.6e-22 78.1 8.2 2.4e-07 30.8 0.3 7.2 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 CRK28520.1 - 7.9e-16 57.6 8.9 5.5e-06 26.2 0.0 6.9 7 0 0 7 7 7 4 Kelch motif Kelch_1 PF01344.25 CRK28520.1 - 2.5e-15 55.8 4.7 3.9e-09 36.0 0.0 5.7 6 0 0 6 6 6 3 Kelch motif Kelch_6 PF13964.6 CRK28520.1 - 1.3e-14 53.8 6.4 2.3e-07 30.8 0.0 5.9 5 2 2 7 7 7 2 Kelch motif Kelch_2 PF07646.15 CRK28520.1 - 2.4e-14 52.7 2.7 2.1e-08 33.8 0.0 4.8 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 CRK28520.1 - 4.8e-12 45.7 12.3 0.0016 18.4 0.1 6.9 7 1 0 7 7 7 4 Galactose oxidase, central domain 2Fe-2S_thioredx PF01257.19 CRK28522.1 - 4.7e-58 195.2 0.0 6.1e-58 194.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin PCI PF01399.27 CRK28524.1 - 0.00046 20.6 0.0 0.00093 19.7 0.0 1.4 1 0 0 1 1 1 1 PCI domain Rep_fac-A_C PF08646.10 CRK28525.1 - 1.6e-55 186.8 5.3 2.6e-54 182.9 2.2 2.3 2 0 0 2 2 2 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 CRK28525.1 - 2e-39 133.4 0.8 7.1e-39 131.7 0.6 2.0 2 0 0 2 2 2 1 Replication protein A OB domain tRNA_anti-codon PF01336.25 CRK28525.1 - 7.7e-15 54.6 0.1 5e-11 42.4 0.0 3.6 3 1 0 3 3 3 2 OB-fold nucleic acid binding domain Rep-A_N PF04057.12 CRK28525.1 - 3.9e-08 33.2 0.2 7.9e-08 32.2 0.2 1.6 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain CDC24_OB3 PF17244.2 CRK28525.1 - 1.3e-05 25.0 0.6 0.013 15.3 0.2 3.0 3 0 0 3 3 3 2 Cell division control protein 24, OB domain 3 DUF5521 PF17659.1 CRK28525.1 - 0.0077 14.1 0.1 0.047 11.6 0.1 1.8 1 1 0 1 1 1 1 Family of unknown function (DUF5521) DUF223 PF02721.14 CRK28525.1 - 0.071 13.4 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF223 zf-like PF04071.12 CRK28525.1 - 0.083 12.8 0.7 0.21 11.5 0.7 1.6 1 0 0 1 1 1 0 Cysteine-rich small domain DLH PF01738.18 CRK28527.1 - 1.4e-17 64.0 0.0 3.1e-08 33.4 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family ADH_zinc_N PF00107.26 CRK28529.1 - 7.1e-23 81.0 0.6 1.4e-22 80.0 0.6 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CRK28529.1 - 1.2e-21 78.2 0.0 1.9e-21 77.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CRK28529.1 - 3.8e-07 30.0 0.0 5e-06 26.4 0.0 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Tyrosinase PF00264.20 CRK28535.1 - 2.7e-48 165.2 0.0 3.4e-48 164.8 0.0 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase NmrA PF05368.13 CRK28536.1 - 2.3e-31 109.1 0.0 2.6e-31 109.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 CRK28536.1 - 3e-08 33.8 0.1 4.8e-08 33.1 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 CRK28536.1 - 7.6e-05 22.3 0.1 0.00012 21.6 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 CRK28536.1 - 0.011 16.0 0.1 0.016 15.5 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 CRK28536.1 - 0.032 14.2 0.2 0.048 13.6 0.2 1.2 1 0 0 1 1 1 0 KR domain 3Beta_HSD PF01073.19 CRK28536.1 - 0.033 13.2 0.0 0.046 12.7 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Fungal_trans PF04082.18 CRK28537.1 - 2.7e-37 128.2 1.0 4.5e-37 127.5 1.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK28537.1 - 5.7e-09 35.9 10.8 1.2e-08 34.9 10.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 CRK28539.1 - 2.7e-51 173.8 0.1 3.5e-51 173.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK28539.1 - 5.7e-35 121.0 0.1 7.2e-35 120.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK28539.1 - 1.1e-12 48.2 0.0 1.6e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 CRK28539.1 - 0.00077 18.7 0.1 0.01 15.0 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Rtt106_N PF18215.1 CRK28539.1 - 0.03 14.1 0.2 2.9 7.7 0.0 2.6 2 0 0 2 2 2 0 Histone chaperone Rtt106 N-terminal domain RuvC PF02075.17 CRK28539.1 - 0.069 13.0 0.0 0.27 11.1 0.0 2.0 2 0 0 2 2 2 0 Crossover junction endodeoxyribonuclease RuvC BAT PF15915.5 CRK28539.1 - 0.099 12.5 0.1 1.4 8.8 0.0 2.3 2 0 0 2 2 2 0 GAF and HTH_10 associated domain CABS1 PF15367.6 CRK28539.1 - 0.12 11.5 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 Calcium-binding and spermatid-specific protein 1 Delta_lysin PF05372.11 CRK28539.1 - 0.16 11.2 0.2 0.41 10.0 0.2 1.7 1 0 0 1 1 1 0 Delta lysin family DHDPS PF00701.22 CRK28541.1 - 5e-43 146.9 0.0 5.9e-43 146.6 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family HsbA PF12296.8 CRK28541.1 - 0.1 13.0 0.2 0.24 11.8 0.2 1.6 1 0 0 1 1 1 0 Hydrophobic surface binding protein A MR_MLE_C PF13378.6 CRK28545.1 - 8.5e-46 156.3 0.3 1.2e-45 155.8 0.3 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 CRK28545.1 - 0.044 14.0 0.0 0.097 12.9 0.0 1.6 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain adh_short PF00106.25 CRK28547.1 - 2.2e-47 161.0 0.1 2.8e-47 160.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK28547.1 - 1.1e-43 149.5 0.0 2e-39 135.6 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK28547.1 - 6.8e-06 26.1 0.2 1.3e-05 25.2 0.2 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 CRK28547.1 - 0.0042 16.6 0.0 0.0081 15.7 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 CRK28547.1 - 0.02 14.8 0.0 0.028 14.3 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 CRK28547.1 - 0.054 12.6 0.0 0.078 12.1 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 CRK28547.1 - 0.073 12.4 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase PALP PF00291.25 CRK28547.1 - 0.086 12.2 0.5 0.54 9.6 0.0 2.0 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme 3Beta_HSD PF01073.19 CRK28547.1 - 0.12 11.4 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family FAD_binding_4 PF01565.23 CRK28549.1 - 1.3e-18 67.0 1.1 2.2e-18 66.4 1.1 1.3 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.14 CRK28549.1 - 2.9e-08 33.8 1.7 0.00026 20.9 0.6 3.4 2 1 0 2 2 2 2 D-arabinono-1,4-lactone oxidase DUF3157 PF11355.8 CRK28549.1 - 0.091 12.4 0.0 2.5 7.7 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3157) Pal1 PF08316.11 CRK28553.1 - 1.7e-111 369.0 13.5 3.3e-46 157.5 0.5 4.6 4 0 0 4 4 4 4 Pal1 cell morphology protein CBM_1 PF00734.18 CRK28553.1 - 7.2e-11 41.8 16.3 1.3e-10 41.0 16.3 1.5 1 0 0 1 1 1 1 Fungal cellulose binding domain Peptidase_S9 PF00326.21 CRK28553.1 - 0.0082 15.6 0.1 0.016 14.7 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family MAT1 PF06391.13 CRK28553.1 - 0.022 14.6 26.5 1.9 8.3 0.2 4.7 5 0 0 5 5 5 0 CDK-activating kinase assembly factor MAT1 Esterase_phd PF10503.9 CRK28553.1 - 0.024 14.2 0.1 0.051 13.1 0.1 1.5 1 0 0 1 1 1 0 Esterase PHB depolymerase DUF4778 PF16008.5 CRK28553.1 - 0.068 13.2 29.5 0.25 11.4 1.1 4.3 3 1 1 4 4 4 0 Domain of unknown function (DUF4778) Glyco_trans_4_4 PF13579.6 CRK28553.1 - 0.15 12.5 17.3 7.6 7.0 0.8 4.9 4 0 0 4 4 4 0 Glycosyl transferase 4-like domain Abhydrolase_2 PF02230.16 CRK28553.1 - 0.23 11.2 0.0 0.38 10.5 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase FDF PF09532.10 CRK28553.1 - 8.1 7.4 20.7 53 4.8 0.7 5.0 4 0 0 4 4 4 0 FDF domain Patatin PF01734.22 CRK28557.1 - 5.1e-22 79.1 0.0 1.6e-21 77.5 0.0 1.9 1 1 0 1 1 1 1 Patatin-like phospholipase NB-ARC PF00931.22 CRK28557.1 - 7.8e-09 35.1 0.0 1.6e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 CRK28557.1 - 1.4e-06 28.6 0.0 8.1e-06 26.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CRK28557.1 - 0.0018 18.7 2.0 0.004 17.6 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 CRK28557.1 - 0.0025 17.4 0.0 0.006 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CRK28557.1 - 0.011 15.7 0.0 0.19 11.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain TPR_12 PF13424.6 CRK28557.1 - 0.028 14.7 1.1 28 5.1 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat SurA_N_2 PF13623.6 CRK28557.1 - 0.031 14.1 3.6 1.2 9.0 2.3 2.4 2 0 0 2 2 2 0 SurA N-terminal domain TPR_4 PF07721.14 CRK28557.1 - 0.043 14.4 1.9 78 4.3 0.0 4.7 3 0 0 3 3 3 0 Tetratricopeptide repeat CbiA PF01656.23 CRK28557.1 - 0.05 13.7 0.0 0.12 12.4 0.0 1.8 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain NACHT PF05729.12 CRK28557.1 - 0.09 12.7 0.0 0.24 11.3 0.0 1.8 1 0 0 1 1 1 0 NACHT domain IstB_IS21 PF01695.17 CRK28557.1 - 0.14 11.9 0.0 0.71 9.6 0.0 2.2 1 0 0 1 1 1 0 IstB-like ATP binding protein SurA_N_3 PF13624.6 CRK28557.1 - 0.41 10.4 4.3 0.38 10.5 1.2 2.4 2 0 0 2 2 2 0 SurA N-terminal domain PT PF04886.12 CRK28560.1 - 0.032 13.8 7.3 0.033 13.7 7.3 1.2 1 0 0 1 1 1 0 PT repeat ALIX_LYPXL_bnd PF13949.6 CRK28562.1 - 0.0075 15.6 0.3 0.011 15.1 0.3 1.2 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV MCC-bdg_PDZ PF10506.9 CRK28562.1 - 0.024 14.6 0.8 0.059 13.4 0.0 1.9 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF2951 PF11166.8 CRK28562.1 - 0.14 12.4 0.9 0.21 11.8 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) DUF1664 PF07889.12 CRK28562.1 - 0.19 11.8 0.7 0.29 11.2 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Macoilin PF09726.9 CRK28563.1 - 6 5.3 10.5 6.6 5.2 10.5 1.0 1 0 0 1 1 1 0 Macoilin family DB PF01682.19 CRK28564.1 - 0.0075 16.6 1.9 0.0075 16.6 1.9 1.9 2 0 0 2 2 2 1 DB module Ank_3 PF13606.6 CRK28565.1 - 1.4e-07 31.2 0.0 0.043 14.4 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 CRK28565.1 - 7.2e-05 23.3 0.0 0.49 11.0 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CRK28565.1 - 0.0011 19.2 0.1 0.75 10.2 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 CRK28565.1 - 0.0012 19.3 0.0 0.74 10.5 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 CRK28565.1 - 0.012 16.0 0.0 0.61 10.6 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeat OTT_1508_deam PF14441.6 CRK28567.1 - 1.9e-15 56.6 0.1 3.5e-15 55.7 0.1 1.4 1 0 0 1 1 1 1 OTT_1508-like deaminase NB-ARC PF00931.22 CRK28568.1 - 0.004 16.4 0.0 0.0072 15.5 0.0 1.4 1 1 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 CRK28568.1 - 0.056 13.8 0.0 0.08 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Pkinase PF00069.25 CRK28570.1 - 2.9e-09 36.7 0.0 3.6e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 CRK28570.1 - 1.6e-08 33.8 0.0 2.1e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 CRK28570.1 - 0.0062 15.8 0.0 0.019 14.3 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase NB-ARC PF00931.22 CRK28571.1 - 9.8e-11 41.3 0.0 1.6e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain TPR_12 PF13424.6 CRK28571.1 - 1.8e-09 37.7 0.5 6.1e-09 36.1 0.5 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 CRK28571.1 - 3.4e-06 26.8 1.9 0.016 15.1 0.3 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat PGAP1 PF07819.13 CRK28571.1 - 9.9e-06 25.4 0.1 4.5e-05 23.3 0.0 2.0 2 1 0 2 2 2 1 PGAP1-like protein AAA_22 PF13401.6 CRK28571.1 - 2.6e-05 24.5 0.0 0.00015 22.1 0.0 2.3 2 0 0 2 2 1 1 AAA domain NACHT PF05729.12 CRK28571.1 - 0.00033 20.6 0.0 0.0006 19.8 0.0 1.4 1 0 0 1 1 1 1 NACHT domain TPR_20 PF14561.6 CRK28571.1 - 0.00048 20.4 4.9 0.33 11.3 0.2 3.3 3 1 0 3 3 3 2 Tetratricopeptide repeat AAA_16 PF13191.6 CRK28571.1 - 0.0008 19.8 3.8 0.0065 16.9 0.2 3.7 3 1 0 3 3 2 1 AAA ATPase domain TPR_19 PF14559.6 CRK28571.1 - 0.00083 19.8 0.8 0.00083 19.8 0.8 3.0 3 1 1 4 4 3 1 Tetratricopeptide repeat DUF676 PF05057.14 CRK28571.1 - 0.0035 16.9 0.0 0.0099 15.4 0.0 1.7 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.20 CRK28571.1 - 0.0037 16.9 0.0 0.0063 16.2 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold LCAT PF02450.15 CRK28571.1 - 0.0057 15.9 0.0 0.0095 15.1 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase TPR_6 PF13174.6 CRK28571.1 - 0.0094 16.5 0.8 3.3 8.6 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat Hydrolase_4 PF12146.8 CRK28571.1 - 0.03 13.6 0.0 0.079 12.2 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 ANAPC3 PF12895.7 CRK28571.1 - 0.057 13.6 0.1 1.5 9.1 0.0 2.9 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Ser_hydrolase PF06821.13 CRK28571.1 - 0.066 13.1 0.9 0.36 10.7 0.0 2.3 2 0 0 2 2 2 0 Serine hydrolase TPR_2 PF07719.17 CRK28571.1 - 0.069 13.3 0.6 7.2 7.0 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 CRK28571.1 - 0.27 12.0 3.0 6.2 7.8 0.2 3.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 CRK28571.1 - 2.5 9.2 8.5 1.1 10.3 0.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat RHSP PF07999.11 CRK28573.1 - 0.089 11.6 0.0 0.1 11.4 0.0 1.1 1 0 0 1 1 1 0 Retrotransposon hot spot protein Arf PF00025.21 CRK28574.1 - 8.8e-38 129.5 0.0 1.2e-24 86.7 0.0 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.20 CRK28574.1 - 3.7e-11 42.8 0.0 2.7e-06 26.8 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 CRK28574.1 - 4.5e-09 36.6 0.0 1.7e-08 34.7 0.0 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CRK28574.1 - 1.1e-08 34.9 0.0 0.0002 21.0 0.0 2.2 2 0 0 2 2 2 2 Ras family SRPRB PF09439.10 CRK28574.1 - 1.9e-06 27.4 0.1 0.00011 21.7 0.0 2.7 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CRK28574.1 - 5.9e-06 25.8 0.0 7.5e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CRK28574.1 - 0.00032 20.3 0.0 0.0014 18.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CRK28574.1 - 0.022 14.9 0.0 0.037 14.1 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase RNase_PH PF01138.21 CRK28575.1 - 2e-23 83.3 0.0 3.5e-23 82.6 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CRK28575.1 - 2.4e-10 40.3 0.0 4.9e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Cwf_Cwc_15 PF04889.12 CRK28576.1 - 8.9e-63 212.3 15.3 1e-62 212.1 15.3 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.12 CRK28576.1 - 0.003 17.0 15.2 0.0034 16.9 15.2 1.1 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 CRK28576.1 - 0.0038 15.5 15.0 0.0038 15.5 15.0 1.0 1 0 0 1 1 1 1 Nop14-like family AAA_11 PF13086.6 CRK28576.1 - 0.074 12.8 0.4 0.073 12.8 0.4 1.1 1 0 0 1 1 1 0 AAA domain SAPS PF04499.15 CRK28576.1 - 0.66 8.7 4.9 0.67 8.7 4.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RR_TM4-6 PF06459.12 CRK28576.1 - 1 9.1 5.8 1.5 8.6 5.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MFAP1 PF06991.11 CRK28576.1 - 1.1 9.1 20.5 2.1 8.2 20.5 1.4 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing DUF3381 PF11861.8 CRK28576.1 - 1.1 9.0 19.4 1.9 8.3 19.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) CDC45 PF02724.14 CRK28576.1 - 1.4 7.2 21.5 1.7 6.8 21.5 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop53 PF07767.11 CRK28576.1 - 1.6 8.0 22.0 2.3 7.5 22.0 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) RNA_polI_A34 PF08208.11 CRK28576.1 - 2.2 8.3 10.8 2.7 8.0 10.8 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 CobT PF06213.12 CRK28576.1 - 3.6 6.9 25.6 6.5 6.1 25.6 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SGT1 PF07093.11 CRK28576.1 - 5.6 5.3 13.2 7.3 4.9 13.2 1.1 1 0 0 1 1 1 0 SGT1 protein SIR4_SID PF16991.5 CRK28576.1 - 9.4 6.3 8.9 13 5.8 8.9 1.2 1 0 0 1 1 1 0 Sir4 SID domain zf-C3HC4_3 PF13920.6 CRK28577.1 - 0.00039 20.2 12.2 0.00059 19.6 12.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 CRK28577.1 - 0.049 13.5 7.5 0.085 12.7 7.5 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 CRK28577.1 - 4.1 7.4 12.5 6.7 6.8 12.5 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Cyt-b5 PF00173.28 CRK28578.1 - 9.4e-21 73.7 0.1 3.3e-12 46.4 0.0 3.8 3 0 0 3 3 3 3 Cytochrome b5-like Heme/Steroid binding domain Ras PF00071.22 CRK28578.1 - 6.3e-07 29.1 0.0 1.1e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Ras family DUF3759 PF12585.8 CRK28579.1 - 2e-40 136.7 5.7 3.4e-40 136.0 5.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) GST_N_3 PF13417.6 CRK28580.1 - 9.9e-16 57.9 0.0 1.8e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 CRK28580.1 - 1.7e-14 53.9 0.0 3.1e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CRK28580.1 - 1.9e-14 53.7 0.0 3.2e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 CRK28580.1 - 0.00052 20.2 0.0 0.0009 19.4 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin GST_C_3 PF14497.6 CRK28580.1 - 0.015 15.5 0.0 0.027 14.6 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CRK28580.1 - 0.017 15.1 0.2 0.046 13.7 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CRK28580.1 - 0.15 12.3 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glyco_hydro_31 PF01055.26 CRK28581.1 - 9.9e-120 400.7 8.5 4.7e-96 322.7 1.2 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 CRK28581.1 - 5.1e-24 84.4 0.1 1.3e-23 83.1 0.1 1.7 1 0 0 1 1 1 1 Galactose mutarotase-like MS_channel PF00924.18 CRK28581.1 - 7.5e-20 71.4 0.5 1.2e-19 70.6 0.5 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel DUF5110 PF17137.4 CRK28581.1 - 1.2e-06 28.7 1.5 2.1e-06 27.9 0.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF5110) EF-hand_7 PF13499.6 CRK28581.1 - 0.093 13.2 0.1 0.29 11.6 0.1 1.9 1 0 0 1 1 1 0 EF-hand domain pair Phage_sheath_1 PF04984.14 CRK28581.1 - 0.14 12.0 0.1 0.29 11.0 0.1 1.5 1 0 0 1 1 1 0 Phage tail sheath protein subtilisin-like domain NDK PF00334.19 CRK28582.1 - 9e-53 177.9 0.0 1.2e-52 177.5 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Lectin_N PF03954.14 CRK28582.1 - 0.24 11.2 0.0 0.37 10.5 0.0 1.3 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain FLILHELTA PF10306.9 CRK28583.1 - 1.2e-27 96.1 0.2 2e-27 95.4 0.2 1.4 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.13 CRK28583.1 - 0.018 15.6 0.1 0.027 15.0 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1279) Na_Ca_ex PF01699.24 CRK28584.1 - 3.8e-30 104.9 40.9 2.6e-18 66.4 15.6 3.0 2 1 0 2 2 2 2 Sodium/calcium exchanger protein DUF2569 PF10754.9 CRK28584.1 - 0.73 10.3 21.7 0.026 14.9 7.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2569) Glyco_hydro_3 PF00933.21 CRK28585.1 - 4.4e-51 174.2 0.0 5.4e-51 173.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain DUF4345 PF14248.6 CRK28587.1 - 0.043 13.7 0.1 0.053 13.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4345) Reticulon PF02453.17 CRK28587.1 - 0.085 12.8 0.1 0.13 12.3 0.1 1.2 1 0 0 1 1 1 0 Reticulon Methyltransf_11 PF08241.12 CRK28589.1 - 4.9e-08 33.5 0.0 7.7e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK28589.1 - 3.1e-06 27.1 0.0 4.3e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK28589.1 - 5e-06 27.1 0.0 1.1e-05 26.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK28589.1 - 0.0028 18.3 0.0 0.004 17.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Egh16-like PF11327.8 CRK28590.1 - 2.9e-52 177.8 10.9 3.7e-52 177.4 10.9 1.1 1 0 0 1 1 1 1 Egh16-like virulence factor NmrA PF05368.13 CRK28591.1 - 3.2e-58 197.1 0.0 3.7e-58 196.8 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 CRK28591.1 - 2.1e-13 50.6 0.1 2.7e-13 50.2 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 CRK28591.1 - 0.00031 20.3 0.1 0.00056 19.5 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1810 PF08837.11 CRK28591.1 - 0.13 12.1 0.0 0.65 9.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1810) Pectate_lyase PF03211.13 CRK28592.1 - 1.2e-65 220.9 2.2 2.2e-65 220.0 2.2 1.4 1 1 0 1 1 1 1 Pectate lyase MFS_1 PF07690.16 CRK28592.1 - 2.8e-20 72.5 43.0 2.8e-20 72.5 43.0 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 CRK28592.1 - 3.8e-08 32.2 21.8 7.2e-08 31.3 21.8 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 CRK28593.1 - 7.1e-44 150.2 17.3 7.1e-44 150.2 17.3 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK28593.1 - 1.3e-16 60.5 0.2 1.3e-16 60.5 0.2 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 CRK28593.1 - 2e-05 23.1 5.9 3.9e-05 22.2 4.4 2.2 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family DUF2105 PF09878.9 CRK28593.1 - 0.0067 16.2 1.1 0.015 15.1 1.1 1.5 1 0 0 1 1 1 1 Predicted membrane protein (DUF2105) DUF4969 PF16339.5 CRK28593.1 - 0.072 13.4 0.3 0.18 12.2 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4969) 5_nucleotid_C PF02872.18 CRK28594.1 - 9.6e-40 136.4 0.0 1.6e-39 135.7 0.0 1.3 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 CRK28594.1 - 0.0091 16.5 0.3 0.12 12.8 0.4 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_3_C PF01915.22 CRK28595.1 - 4.7e-55 186.7 0.0 1.4e-54 185.1 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 CRK28595.1 - 1.6e-54 185.4 0.0 2.6e-54 184.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 CRK28595.1 - 4.3e-22 78.0 0.8 8.2e-22 77.1 0.3 1.8 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.12 CRK28595.1 - 0.00041 20.2 0.0 0.0009 19.1 0.0 1.5 1 0 0 1 1 1 1 PA14 domain DUF3636 PF12331.8 CRK28596.1 - 1.3e-38 132.1 0.7 2.6e-38 131.2 0.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) ECH_1 PF00378.20 CRK28596.1 - 1e-15 57.8 1.5 1.8e-15 56.9 0.0 1.9 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase DUF812 PF05667.11 CRK28596.1 - 0.0057 15.6 1.7 0.0087 15.0 1.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Formyl_trans_N PF00551.19 CRK28596.1 - 0.01 15.6 0.9 0.046 13.4 0.0 2.3 2 1 0 2 2 2 0 Formyl transferase TMF_TATA_bd PF12325.8 CRK28596.1 - 0.077 13.2 7.5 0.14 12.4 7.5 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Formyl_trans_C PF02911.18 CRK28596.1 - 0.092 13.0 0.0 0.32 11.2 0.0 1.9 1 0 0 1 1 1 0 Formyl transferase, C-terminal domain K-box PF01486.17 CRK28596.1 - 0.23 11.7 2.7 0.7 10.1 2.7 1.8 1 0 0 1 1 1 0 K-box region CRAL_TRIO PF00650.20 CRK28598.1 - 4.7e-38 130.4 0.0 1.1e-37 129.2 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CRK28598.1 - 5.1e-14 52.2 0.1 1.6e-13 50.6 0.0 1.9 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 CRK28598.1 - 1e-08 35.4 0.0 1.6e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DNA_pol_A_exoN PF18305.1 CRK28598.1 - 0.13 12.6 0.1 0.28 11.5 0.1 1.6 1 0 0 1 1 1 0 3' to 5' exonuclease C-terminal domain Fungal_trans_2 PF11951.8 CRK28599.1 - 2.3e-08 33.3 0.2 4.1e-07 29.1 0.1 2.5 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK28599.1 - 0.00054 20.0 1.1 0.0011 19.0 1.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ILVD_EDD PF00920.21 CRK28602.1 - 2.9e-27 95.5 0.1 3.1e-27 95.4 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family EFG_C PF00679.24 CRK28603.1 - 3.2e-16 59.1 0.0 5.7e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G C-terminus Paf67 PF10255.9 CRK28604.1 - 8.6e-134 446.5 3.0 4.1e-78 263.2 0.1 2.4 1 1 1 2 2 2 2 RNA polymerase I-associated factor PAF67 Usp PF00582.26 CRK28604.1 - 1.4e-14 54.8 6.9 3.8e-14 53.4 0.0 3.8 4 0 0 4 4 4 1 Universal stress protein family EOS1 PF12326.8 CRK28604.1 - 0.071 13.0 0.4 0.19 11.7 0.4 1.7 1 0 0 1 1 1 0 N-glycosylation protein Neur_chan_memb PF02932.16 CRK28604.1 - 0.19 11.7 2.6 0.22 11.6 1.0 1.9 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Spem1 PF15670.5 CRK28604.1 - 0.46 10.0 10.1 1.2 8.7 10.1 1.7 1 0 0 1 1 1 0 Spermatid maturation protein 1 Zip PF02535.22 CRK28604.1 - 1.4 8.1 8.4 3.1 6.9 8.4 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4834 PF16118.5 CRK28604.1 - 1.6 9.8 7.6 0.21 12.6 2.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) SelP_N PF04592.14 CRK28604.1 - 2.9 7.3 22.8 6.3 6.1 22.8 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF2828 PF11443.8 CRK28604.1 - 8.7 4.3 11.6 15 3.5 11.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Connexin PF00029.19 CRK28604.1 - 9.8 5.9 11.3 25 4.5 11.3 1.6 1 0 0 1 1 1 0 Connexin NB-ARC PF00931.22 CRK28607.1 - 2.9e-05 23.4 0.0 4.6e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_25 PF13481.6 CRK28607.1 - 0.011 15.4 0.0 0.019 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain PNP_UDP_1 PF01048.20 CRK28608.1 - 0.0026 17.0 0.0 0.0037 16.5 0.0 1.4 1 1 0 1 1 1 1 Phosphorylase superfamily Amidase PF01425.21 CRK28610.1 - 5.6e-71 239.8 0.4 4.2e-69 233.7 0.0 2.1 2 0 0 2 2 2 2 Amidase Glyco_transf_64 PF09258.10 CRK28612.1 - 1.5e-49 168.5 0.0 2e-49 168.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain TPT PF03151.16 CRK28613.1 - 2.4e-25 89.5 24.0 3.4e-25 89.0 24.0 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family NADH-u_ox-rdase PF10785.9 CRK28613.1 - 0.67 10.7 4.5 0.8 10.4 0.2 3.1 2 1 0 2 2 2 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit OPT PF03169.15 CRK28631.1 - 1.1e-23 83.8 0.1 1.1e-23 83.7 0.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3611 PF12263.8 CRK28631.1 - 0.013 15.4 0.2 0.014 15.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) Mg_trans_NIPA PF05653.14 CRK28631.1 - 0.035 13.2 0.0 0.035 13.2 0.0 1.1 1 0 0 1 1 1 0 Magnesium transporter NIPA CMV_US PF08001.11 CRK28631.1 - 0.038 13.3 0.1 0.041 13.1 0.1 1.1 1 0 0 1 1 1 0 CMV US AAA PF00004.29 CRK28634.1 - 1.5e-98 326.3 0.0 7.4e-48 162.3 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CRK28634.1 - 1.2e-24 85.8 3.4 5.5e-13 48.5 0.3 3.3 2 1 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 CRK28634.1 - 8.8e-15 54.8 0.0 2.4e-06 27.4 0.0 3.1 4 1 0 4 4 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 CRK28634.1 - 4.6e-14 52.9 0.0 1.5e-07 31.7 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 CRK28634.1 - 7e-14 52.6 0.0 0.00013 22.4 0.0 4.3 2 2 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 CRK28634.1 - 2.2e-12 47.2 0.5 2.4e-06 27.6 0.1 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 CRK28634.1 - 3.5e-12 46.7 0.0 3.2e-05 24.1 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.6 CRK28634.1 - 5.8e-10 39.6 0.4 0.025 14.8 0.0 4.1 2 2 2 4 4 4 2 AAA domain TIP49 PF06068.13 CRK28634.1 - 2.1e-09 37.0 0.0 0.00081 18.7 0.0 2.5 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_18 PF13238.6 CRK28634.1 - 1.1e-07 32.5 0.0 0.02 15.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 CRK28634.1 - 1.5e-07 31.0 0.4 0.0064 15.9 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 CRK28634.1 - 2.2e-07 30.8 0.0 0.015 15.1 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein ATPase PF06745.13 CRK28634.1 - 2.9e-07 30.1 0.2 0.19 11.0 0.0 3.4 3 0 0 3 3 3 2 KaiC RNA_helicase PF00910.22 CRK28634.1 - 2.9e-07 30.8 0.0 0.023 15.1 0.0 2.9 3 0 0 3 3 2 2 RNA helicase AAA_14 PF13173.6 CRK28634.1 - 3.6e-07 30.3 0.0 0.0057 16.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 CRK28634.1 - 5.1e-07 29.4 4.0 0.23 11.0 0.1 4.0 2 2 1 4 4 4 3 AAA domain AAA_7 PF12775.7 CRK28634.1 - 5.9e-07 29.2 0.1 0.016 14.7 0.0 3.0 3 1 0 3 3 2 2 P-loop containing dynein motor region AAA_24 PF13479.6 CRK28634.1 - 2.4e-06 27.4 0.0 0.061 13.0 0.0 2.8 3 0 0 3 3 2 2 AAA domain DUF815 PF05673.13 CRK28634.1 - 5e-06 25.9 0.0 0.013 14.6 0.0 2.6 2 1 0 2 2 2 2 Protein of unknown function (DUF815) Parvo_NS1 PF01057.17 CRK28634.1 - 5.5e-06 25.7 0.0 0.039 13.1 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 CRK28634.1 - 1e-05 25.9 0.0 0.13 12.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 CRK28634.1 - 1e-05 25.3 0.1 0.17 11.6 0.0 3.4 2 2 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.27 CRK28634.1 - 1.4e-05 25.7 0.0 0.25 11.9 0.0 3.3 2 1 0 2 2 2 2 ABC transporter Bac_DnaA PF00308.18 CRK28634.1 - 2.3e-05 24.4 0.0 0.08 12.8 0.0 2.7 3 0 0 3 3 2 2 Bacterial dnaA protein Vps4_C PF09336.10 CRK28634.1 - 3.7e-05 23.6 0.3 0.00051 20.0 0.1 2.6 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain TsaE PF02367.17 CRK28634.1 - 5.3e-05 23.2 0.0 0.35 10.9 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 CRK28634.1 - 7.3e-05 22.7 0.1 0.13 12.1 0.0 2.9 3 0 0 3 3 3 1 NACHT domain ResIII PF04851.15 CRK28634.1 - 9.5e-05 22.5 0.0 0.032 14.2 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_3 PF07726.11 CRK28634.1 - 0.00012 21.9 0.0 0.49 10.3 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 CRK28634.1 - 0.00015 22.2 0.0 0.43 11.0 0.0 2.8 3 0 0 3 3 2 2 AAA domain PhoH PF02562.16 CRK28634.1 - 0.00016 21.2 0.3 0.53 9.7 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_30 PF13604.6 CRK28634.1 - 0.00023 20.9 0.2 0.74 9.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.6 CRK28634.1 - 0.00026 20.9 0.0 0.94 9.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 CRK28634.1 - 0.00031 20.7 0.0 1.3 8.8 0.0 3.5 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_19 PF13245.6 CRK28634.1 - 0.0006 20.2 0.5 4.4 7.6 0.0 3.6 3 1 0 4 4 4 0 AAA domain DUF2075 PF09848.9 CRK28634.1 - 0.0011 18.3 0.0 1.2 8.4 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Sigma54_activ_2 PF14532.6 CRK28634.1 - 0.002 18.2 0.0 0.37 10.9 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain NTPase_1 PF03266.15 CRK28634.1 - 0.0028 17.6 0.4 1.9 8.4 0.0 3.7 3 0 0 3 3 3 1 NTPase NB-ARC PF00931.22 CRK28634.1 - 0.0033 16.6 0.0 1.3 8.1 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain KAP_NTPase PF07693.14 CRK28634.1 - 0.0044 16.3 0.4 0.66 9.1 0.0 3.4 2 2 2 4 4 4 1 KAP family P-loop domain Viral_helicase1 PF01443.18 CRK28634.1 - 0.0052 16.5 0.0 0.25 11.0 0.0 2.2 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase IPT PF01745.16 CRK28634.1 - 0.0075 15.7 0.0 1.4 8.3 0.0 2.3 2 0 0 2 2 2 1 Isopentenyl transferase Zeta_toxin PF06414.12 CRK28634.1 - 0.014 14.7 0.5 6.1 6.1 0.0 2.9 3 0 0 3 3 2 0 Zeta toxin AAA_6 PF12774.7 CRK28634.1 - 0.023 13.7 0.2 5.7 5.8 0.0 2.6 3 0 0 3 3 2 0 Hydrolytic ATP binding site of dynein motor region Cytidylate_kin2 PF13189.6 CRK28634.1 - 0.025 14.7 0.2 3.6 7.7 0.0 2.9 3 0 0 3 3 3 0 Cytidylate kinase-like family Zot PF05707.12 CRK28634.1 - 0.031 13.9 0.2 1.7 8.2 0.0 3.1 2 2 0 2 2 2 0 Zonular occludens toxin (Zot) Cytidylate_kin PF02224.18 CRK28634.1 - 0.033 13.9 0.0 7.6 6.2 0.0 2.7 2 0 0 2 2 2 0 Cytidylate kinase CDC48_2 PF02933.17 CRK28634.1 - 0.046 13.5 0.1 0.086 12.6 0.1 1.5 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 AFG1_ATPase PF03969.16 CRK28634.1 - 0.06 12.2 0.0 9 5.1 0.0 2.2 2 0 0 2 2 2 0 AFG1-like ATPase TniB PF05621.11 CRK28634.1 - 0.13 11.6 0.1 18 4.7 0.0 2.9 3 0 0 3 3 3 0 Bacterial TniB protein AAA_29 PF13555.6 CRK28634.1 - 0.16 11.7 0.0 26 4.6 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Adeno_IVa2 PF02456.15 CRK28634.1 - 0.23 10.2 0.0 10 4.8 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein CDC48_N PF02359.18 CRK28635.1 - 5.7e-20 71.3 0.4 7.5e-20 70.9 0.4 1.2 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain eIF-1a PF01176.19 CRK28635.1 - 0.096 12.5 2.6 1.3 8.9 0.1 2.9 1 1 1 2 2 2 0 Translation initiation factor 1A / IF-1 YjeF_N PF03853.15 CRK28636.1 - 1.3e-40 139.1 0.3 1.8e-40 138.6 0.3 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.10 CRK28636.1 - 1e-08 36.0 2.0 3.8e-08 34.1 2.0 2.0 1 0 0 1 1 1 1 FDF domain PIF1 PF05970.14 CRK28637.1 - 1.3e-57 195.6 0.1 5.4e-55 187.0 0.1 2.2 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 CRK28637.1 - 5.8e-19 68.6 0.0 1e-18 67.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CRK28637.1 - 9.4e-10 39.0 0.0 1.9e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CRK28637.1 - 3.9e-05 23.9 0.0 0.0001 22.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 CRK28637.1 - 0.00017 21.2 0.0 0.00034 20.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 CRK28637.1 - 0.00022 21.6 0.0 0.00051 20.5 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain UvrD_C_2 PF13538.6 CRK28637.1 - 0.0004 20.2 0.1 0.00092 19.0 0.1 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.14 CRK28637.1 - 0.00046 18.3 0.0 0.0015 16.5 0.0 1.7 2 0 0 2 2 2 1 Helicase AAA PF00004.29 CRK28637.1 - 0.00079 19.8 0.0 0.0024 18.3 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 CRK28637.1 - 0.0057 17.2 0.0 0.023 15.2 0.0 2.0 2 0 0 2 2 1 1 ABC transporter PhoH PF02562.16 CRK28637.1 - 0.01 15.3 0.1 0.032 13.7 0.0 1.8 2 0 0 2 2 2 1 PhoH-like protein AAA_5 PF07728.14 CRK28637.1 - 0.012 15.6 0.1 0.047 13.7 0.1 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 CRK28637.1 - 0.013 15.9 0.0 0.028 14.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.22 CRK28637.1 - 0.018 14.3 0.0 0.034 13.3 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain T2SSE PF00437.20 CRK28637.1 - 0.018 14.1 0.1 0.031 13.3 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF2075 PF09848.9 CRK28637.1 - 0.024 13.9 0.2 0.045 13.0 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DUF815 PF05673.13 CRK28637.1 - 0.025 13.7 0.1 0.066 12.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NACHT PF05729.12 CRK28637.1 - 0.03 14.2 0.0 0.065 13.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain IstB_IS21 PF01695.17 CRK28637.1 - 0.04 13.7 0.0 0.75 9.5 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein RsgA_GTPase PF03193.16 CRK28637.1 - 0.088 12.7 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_11 PF13086.6 CRK28637.1 - 0.092 12.5 0.5 0.35 10.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 CRK28637.1 - 0.11 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SH3_13 PF18335.1 CRK28637.1 - 0.12 12.2 0.0 0.43 10.5 0.0 1.9 2 0 0 2 2 1 0 ATP-dependent RecD-like DNA helicase SH3 domain ATPase_2 PF01637.18 CRK28637.1 - 0.16 11.8 0.0 0.39 10.6 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Peptidase_M14 PF00246.24 CRK28638.1 - 1.9e-13 50.9 0.1 3.1e-13 50.2 0.1 1.4 1 0 0 1 1 1 1 Zinc carboxypeptidase DUF2835 PF11197.8 CRK28638.1 - 0.047 13.5 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2835) DpnI_C PF17726.1 CRK28638.1 - 0.054 13.6 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Dam-replacing HTH domain AstE_AspA PF04952.14 CRK28638.1 - 0.086 11.9 0.2 0.23 10.5 0.1 1.8 2 0 0 2 2 2 0 Succinylglutamate desuccinylase / Aspartoacylase family COesterase PF00135.28 CRK28639.1 - 3.3e-82 277.0 0.0 5.1e-82 276.4 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Tyrosinase PF00264.20 CRK28639.1 - 2.3e-43 149.1 0.0 3.6e-43 148.4 0.0 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase Zip PF02535.22 CRK28639.1 - 5.9e-10 38.9 0.3 8.6e-10 38.3 0.3 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Abhydrolase_3 PF07859.13 CRK28639.1 - 5.6e-07 29.6 0.5 2.3e-06 27.6 0.5 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold peroxidase PF00141.23 CRK28640.1 - 1.7e-09 37.7 0.0 0.00045 20.0 0.0 2.4 1 1 1 2 2 2 2 Peroxidase CBM_35 PF16990.5 CRK28641.1 - 0.042 14.1 0.0 0.085 13.1 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate binding module (family 35) PFK PF00365.20 CRK28642.1 - 2.3e-19 69.8 0.0 2.3e-19 69.8 0.0 1.0 1 0 0 1 1 1 1 Phosphofructokinase DAGK_cat PF00781.24 CRK28642.1 - 0.0033 17.0 0.0 0.0036 16.9 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.21 CRK28642.1 - 0.1 11.8 0.0 0.1 11.8 0.0 1.1 1 0 0 1 1 1 0 ATP-NAD kinase Transcrip_reg PF01709.20 CRK28642.1 - 0.18 11.2 0.0 0.18 11.2 0.0 1.1 1 0 0 1 1 1 0 Transcriptional regulator MFS_1 PF07690.16 CRK28646.1 - 2.5e-24 85.9 31.4 3.4e-24 85.5 31.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK28646.1 - 1.5e-13 50.4 17.4 3.4e-13 49.3 17.4 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter ATG22 PF11700.8 CRK28646.1 - 4.2e-08 32.3 11.0 1.1e-07 30.9 4.2 2.9 1 1 2 3 3 3 3 Vacuole effluxer Atg22 like TRI12 PF06609.13 CRK28646.1 - 8.4e-05 21.2 0.9 8.4e-05 21.2 0.9 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Cyclase PF04199.13 CRK28647.1 - 1.7e-12 47.7 0.2 2.3e-12 47.3 0.2 1.2 1 0 0 1 1 1 1 Putative cyclase Gln-synt_C PF00120.24 CRK28648.1 - 1.6e-71 241.1 0.0 2.2e-71 240.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Aminotran_1_2 PF00155.21 CRK28649.1 - 8.5e-24 84.4 0.0 1.7e-23 83.4 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 CRK28649.1 - 0.022 13.3 0.0 0.037 12.6 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 CRK28649.1 - 0.029 13.6 0.0 0.041 13.2 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase adh_short_C2 PF13561.6 CRK28650.1 - 6.6e-32 110.9 0.4 5.4e-31 107.9 0.4 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRK28650.1 - 7.4e-31 107.1 1.1 1.9e-30 105.8 1.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CRK28650.1 - 4.6e-08 33.2 0.1 8.9e-08 32.2 0.1 1.4 1 0 0 1 1 1 1 KR domain zf-C2H2 PF00096.26 CRK28651.1 - 0.19 12.2 0.1 0.19 12.2 0.1 2.9 3 0 0 3 3 3 0 Zinc finger, C2H2 type DIOX_N PF14226.6 CRK28652.1 - 5.5e-28 98.1 0.0 8.4e-28 97.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 CRK28652.1 - 2.2e-11 44.1 0.0 6.3e-11 42.7 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Vac_ImportDeg PF09783.9 CRK28652.1 - 0.15 11.8 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Vacuolar import and degradation protein Peptidase_M54 PF07998.11 CRK28653.1 - 6.5e-08 32.8 0.2 1.1e-07 32.1 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M54 Peptidase_M10 PF00413.24 CRK28653.1 - 0.003 17.4 0.0 0.0046 16.8 0.0 1.3 1 0 0 1 1 1 1 Matrixin Peptidase_M66 PF10462.9 CRK28653.1 - 0.086 11.8 0.1 0.13 11.2 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 Metallopep PF12044.8 CRK28653.1 - 0.11 11.1 0.2 0.16 10.6 0.2 1.2 1 0 0 1 1 1 0 Putative peptidase family ADH_N PF08240.12 CRK28654.1 - 8.9e-25 86.7 5.0 1.5e-24 86.0 5.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CRK28654.1 - 3.2e-20 72.4 0.0 1.2e-19 70.6 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 CRK28654.1 - 0.0012 18.3 0.2 0.0023 17.3 0.2 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 CRK28654.1 - 0.0027 17.0 0.0 0.0048 16.2 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain CTP_transf_like PF01467.26 CRK28655.1 - 3.7e-07 30.4 0.7 9.3e-05 22.6 0.4 2.4 2 1 0 2 2 2 2 Cytidylyltransferase-like DUF2229 PF09989.9 CRK28655.1 - 0.084 12.5 0.0 0.55 9.9 0.0 2.1 2 0 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) DUF1674 PF07896.12 CRK28656.1 - 8.4e-19 67.8 3.9 2.2e-18 66.5 3.9 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1674) Rxt3 PF08642.10 CRK28657.1 - 7.5e-09 36.4 2.0 2.9e-08 34.5 0.1 2.2 2 1 0 2 2 2 1 Histone deacetylation protein Rxt3 Rxt3 PF08642.10 CRK28658.1 - 2.7e-43 147.8 0.2 2.7e-43 147.8 0.2 2.8 4 0 0 4 4 4 1 Histone deacetylation protein Rxt3 LCCL PF03815.19 CRK28658.1 - 0.00092 19.3 0.0 0.014 15.5 0.0 2.3 2 0 0 2 2 2 1 LCCL domain Zn_clus PF00172.18 CRK28659.1 - 3.4e-06 27.1 12.0 3.4e-06 27.1 12.0 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 CRK28659.1 - 2.5e-05 23.3 0.7 3.3e-05 22.9 0.7 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Rep_fac-A_C PF08646.10 CRK28659.1 - 0.0003 20.6 0.4 0.00052 19.8 0.4 1.4 1 0 0 1 1 1 1 Replication factor-A C terminal domain ChuX_HutX PF06228.13 CRK28659.1 - 0.038 13.8 0.0 0.051 13.3 0.0 1.2 1 0 0 1 1 1 0 Haem utilisation ChuX/HutX Kinesin PF00225.23 CRK28662.1 - 7.2e-57 192.8 0.0 1.2e-56 192.0 0.0 1.4 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CRK28662.1 - 3.2e-10 40.1 0.0 5.6e-07 29.6 0.0 2.5 2 0 0 2 2 2 2 Microtubule binding EzrA PF06160.12 CRK28662.1 - 0.16 10.1 1.7 0.24 9.5 1.7 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Jnk-SapK_ap_N PF09744.9 CRK28662.1 - 3.3 7.9 10.4 0.37 11.0 4.8 2.0 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 NPP1 PF05630.11 CRK28663.1 - 3.8e-48 164.2 6.0 5.1e-48 163.8 6.0 1.1 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Wzy_C PF04932.15 CRK28664.1 - 0.0069 16.0 11.8 0.39 10.3 0.2 3.3 3 0 0 3 3 3 3 O-Antigen ligase FAD_binding_4 PF01565.23 CRK28665.1 - 6.4e-25 87.5 2.3 1e-24 86.8 2.3 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 CRK28665.1 - 6.8e-09 35.7 0.0 1.2e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like Glyco_transf_54 PF04666.13 CRK28666.1 - 6.7e-14 51.4 0.0 1.3e-06 27.5 0.0 3.2 3 0 0 3 3 3 3 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region YbhQ PF11076.8 CRK28666.1 - 1.5 8.8 4.1 1.5 8.9 2.4 1.8 2 0 0 2 2 2 0 Putative inner membrane protein YbhQ CorA PF01544.18 CRK28667.1 - 0.11 11.7 3.7 0.43 9.8 3.7 1.9 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein MFS_1 PF07690.16 CRK28668.1 - 2.1e-27 96.0 39.7 2.3e-27 95.9 37.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Amidoligase_2 PF12224.8 CRK28668.1 - 9.6e-19 68.0 0.1 4.5e-08 33.1 0.0 4.5 3 2 0 4 4 4 3 Putative amidoligase enzyme MFS_4 PF06779.14 CRK28668.1 - 0.0067 15.8 19.3 0.013 14.8 19.3 1.4 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB TPPK_C PF12555.8 CRK28668.1 - 0.093 12.8 0.4 0.4 10.8 0.4 2.1 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal DUF5107 PF17128.4 CRK28669.1 - 0.028 13.6 1.0 0.067 12.4 0.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF5107) CAP PF00188.26 CRK28670.1 - 2.1e-14 54.4 0.0 3.4e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family ADH_zinc_N PF00107.26 CRK28671.1 - 9.9e-13 48.2 0.1 1.9e-12 47.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CRK28671.1 - 3.3e-07 30.1 0.0 7.7e-07 29.0 0.0 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 CRK28671.1 - 0.0019 19.2 0.0 0.005 17.9 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 CRK28673.1 - 3.2e-22 79.0 0.0 7.8e-22 77.7 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK28673.1 - 7e-18 65.0 0.0 1.4e-17 64.0 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK28673.1 - 1.7e-08 34.6 0.1 2.2e-08 34.2 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CRK28673.1 - 1.5e-06 27.9 0.0 2.1e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 CRK28673.1 - 2.7e-06 27.4 0.1 3.5e-06 27.0 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 CRK28673.1 - 0.00018 21.0 0.0 0.00026 20.5 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase PK_C PF02887.16 CRK28673.1 - 0.079 13.2 0.1 0.13 12.5 0.1 1.3 1 0 0 1 1 1 0 Pyruvate kinase, alpha/beta domain SNF5 PF04855.12 CRK28674.1 - 4.6e-93 311.4 0.0 6.6e-93 310.9 0.0 1.2 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 Glyco_hydro_7 PF00840.20 CRK28675.1 - 2.3e-191 636.2 23.4 2.9e-191 635.9 23.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CBM_1 PF00734.18 CRK28675.1 - 1.5e-12 47.2 16.5 1.5e-12 47.2 16.5 4.4 3 1 0 3 3 3 1 Fungal cellulose binding domain CytadhesinP1 PF12378.8 CRK28675.1 - 0.086 13.0 0.1 0.29 11.3 0.1 1.9 1 0 0 1 1 1 0 Trypsin-sensitive surface-exposed protein HET PF06985.11 CRK28678.1 - 9.9e-12 45.4 6.3 9.9e-10 38.9 0.5 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Kelch_5 PF13854.6 CRK28679.1 - 5.5e-16 58.2 6.0 1.3e-07 31.4 0.0 4.8 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 CRK28679.1 - 2.8e-11 43.2 10.8 0.19 11.8 0.0 6.2 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_3 PF13415.6 CRK28679.1 - 6.4e-08 32.7 10.7 0.0073 16.6 0.1 6.1 5 1 0 5 5 5 2 Galactose oxidase, central domain Kelch_6 PF13964.6 CRK28679.1 - 1.5e-07 31.4 3.0 0.56 10.6 0.1 5.6 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.25 CRK28679.1 - 1.8e-06 27.4 10.0 0.33 10.6 0.1 5.7 6 0 0 6 6 6 2 Kelch motif Kelch_2 PF07646.15 CRK28679.1 - 0.069 13.2 0.1 0.069 13.2 0.1 4.5 6 1 0 6 6 6 0 Kelch motif PBP1_TM PF14812.6 CRK28679.1 - 0.39 11.1 7.4 1.1 9.7 7.4 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC45 PF02724.14 CRK28679.1 - 7.1 4.8 6.2 10 4.3 6.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF19 PF01579.18 CRK28680.1 - 0.039 13.8 4.9 0.91 9.3 0.6 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF19) VPS9 PF02204.18 CRK28683.1 - 1.3e-19 70.3 0.1 3.1e-19 69.1 0.1 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_5 PF13857.6 CRK28683.1 - 3.9e-19 68.5 0.4 4.9e-13 49.0 0.0 5.0 5 1 1 6 6 6 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CRK28683.1 - 3.1e-12 46.9 0.0 0.00011 22.8 0.0 3.9 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CRK28683.1 - 1.4e-08 35.1 0.1 0.11 13.1 0.0 5.0 4 1 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CRK28683.1 - 6.6e-07 29.1 0.1 0.39 11.4 0.0 5.4 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 CRK28683.1 - 0.0037 17.7 0.1 3.3 8.3 0.0 4.0 5 0 0 5 5 5 1 Ankyrin repeat MFS_1 PF07690.16 CRK28686.1 - 3.5e-09 36.1 1.2 2e-08 33.5 0.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK28686.1 - 2.3e-06 26.7 0.2 5.6e-06 25.5 0.2 1.6 1 1 1 2 2 2 1 Sugar (and other) transporter AAA PF00004.29 CRK28687.1 - 1.6e-15 57.7 0.0 4.8e-15 56.2 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CRK28687.1 - 0.004 17.2 0.0 0.0098 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CRK28687.1 - 0.0054 17.0 1.7 0.1 12.9 1.7 2.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CRK28687.1 - 0.0088 16.4 0.5 0.046 14.1 0.5 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 CRK28687.1 - 0.046 14.3 0.3 0.32 11.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 CRK28687.1 - 0.22 11.3 0.0 0.22 11.3 0.0 3.2 3 0 0 3 3 3 0 AAA domain PKD_channel PF08016.12 CRK28688.1 - 3.2e-08 32.7 11.5 4.7e-08 32.1 11.5 1.2 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 CRK28688.1 - 8.3e-08 31.7 18.2 2.2e-07 30.3 18.2 1.7 1 1 0 1 1 1 1 Ion transport protein SUIM_assoc PF16619.5 CRK28688.1 - 0.036 14.1 28.3 0.016 15.2 1.9 4.4 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 TPR_2 PF07719.17 CRK28688.1 - 0.12 12.6 0.9 0.31 11.3 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Cyt-b5 PF00173.28 CRK28689.1 - 6.9e-14 51.7 0.0 1.4e-09 38.0 0.0 3.8 3 0 0 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain Jiv90 PF14901.6 CRK28689.1 - 0.089 13.0 0.4 6.4 7.0 0.0 3.2 3 0 0 3 3 3 0 Cleavage inducing molecular chaperone MFS_1 PF07690.16 CRK28690.1 - 5e-36 124.4 17.8 5.6e-36 124.2 17.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily AltA1 PF16541.5 CRK28691.1 - 2.2e-24 86.5 0.6 2.8e-24 86.1 0.6 1.1 1 0 0 1 1 1 1 Alternaria alternata allergen 1 PRP21_like_P PF12230.8 CRK28709.1 - 4.8e-10 39.7 4.8 5.9e-10 39.4 4.8 1.1 1 0 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein DNA_pol3_a_NII PF11490.8 CRK28709.1 - 0.024 14.5 0.4 0.028 14.3 0.4 1.1 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II Surp PF01805.20 CRK28709.1 - 0.03 14.3 3.7 0.068 13.2 3.7 1.6 1 0 0 1 1 1 0 Surp module PNTB PF02233.16 CRK28715.1 - 1e-173 578.5 28.8 1e-173 578.5 28.8 2.1 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 CRK28715.1 - 7.5e-74 247.6 0.0 7.5e-74 247.6 0.0 2.3 2 0 0 2 2 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 CRK28715.1 - 2.3e-47 160.7 0.0 8.8e-47 158.8 0.0 2.1 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 CRK28715.1 - 9.6e-31 106.1 3.9 9.6e-31 106.1 3.9 5.4 3 1 3 6 6 6 1 4TM region of pyridine nucleotide transhydrogenase, mitoch ADH_zinc_N PF00107.26 CRK28715.1 - 0.001 19.0 2.6 0.0046 16.9 0.0 3.3 3 0 0 3 3 3 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 CRK28715.1 - 0.0016 17.8 0.1 0.45 9.8 0.0 2.5 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TPP_enzyme_M PF00205.22 CRK28715.1 - 0.0084 15.9 0.6 0.14 11.9 0.6 2.9 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Pyr_redox_2 PF07992.14 CRK28715.1 - 0.015 14.5 1.0 0.024 13.9 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CRK28715.1 - 0.019 15.2 0.6 0.13 12.5 0.4 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Methyltransf_23 PF13489.6 CRK28715.1 - 0.034 14.0 0.0 0.068 13.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 CRK28715.1 - 0.088 12.6 0.0 0.41 10.4 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain FAD_binding_2 PF00890.24 CRK28715.1 - 0.31 10.1 3.8 0.6 9.1 1.8 2.2 2 0 0 2 2 2 0 FAD binding domain NDUFA12 PF05071.16 CRK28716.1 - 7.5e-16 58.8 1.2 3.5e-09 37.4 0.0 2.1 1 1 1 2 2 2 2 NADH ubiquinone oxidoreductase subunit NDUFA12 PLDc_2 PF13091.6 CRK28717.1 - 3.3e-17 62.6 0.0 1.6e-07 31.3 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 CRK28717.1 - 1.4e-07 31.4 3.4 0.019 15.2 0.1 3.0 2 1 0 2 2 2 2 Phospholipase D Active site motif Ank_2 PF12796.7 CRK28718.1 - 7.7e-14 52.1 0.6 2.6e-08 34.3 0.0 4.4 3 2 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CRK28718.1 - 8.9e-10 38.9 6.5 0.0016 18.9 0.1 5.5 2 2 4 6 6 6 2 Ankyrin repeats (many copies) Ank PF00023.30 CRK28718.1 - 1.9e-08 34.3 9.1 0.017 15.5 1.0 5.3 5 0 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.6 CRK28718.1 - 4.9e-06 26.5 8.7 0.39 11.4 0.1 6.0 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 CRK28718.1 - 0.0004 20.6 7.4 0.006 16.9 0.2 4.4 3 1 2 5 5 5 1 Ankyrin repeats (many copies) CortBP2 PF09727.9 CRK28720.1 - 0.00081 19.4 1.7 0.0012 18.8 1.7 1.2 1 0 0 1 1 1 1 Cortactin-binding protein-2 DUF4763 PF15960.5 CRK28720.1 - 0.015 14.6 2.1 0.019 14.3 2.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) Pedibin PF08182.11 CRK28720.1 - 0.068 13.0 6.0 0.076 12.8 4.4 1.9 2 0 0 2 2 2 0 Pedibin/Hym-346 family Zn_clus PF00172.18 CRK28722.1 - 8.5e-17 61.0 24.7 8.4e-09 35.4 8.6 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 CRK28722.1 - 1.1e-12 47.6 0.0 1.6e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DNA_pol_viral_C PF00336.18 CRK28722.1 - 0.078 12.4 1.0 11 5.3 0.1 2.3 2 0 0 2 2 2 0 DNA polymerase (viral) C-terminal domain PAP_PilO PF06864.12 CRK28722.1 - 2.7 6.7 15.4 1.2 7.9 2.2 2.3 2 0 0 2 2 2 0 Pilin accessory protein (PilO) Histidinol_dh PF00815.20 CRK28722.1 - 4 6.4 5.0 20 4.1 0.4 2.1 2 0 0 2 2 2 0 Histidinol dehydrogenase Cutinase PF01083.22 CRK28723.1 - 8.1e-41 139.9 0.2 9.5e-41 139.7 0.2 1.0 1 0 0 1 1 1 1 Cutinase VirJ PF06057.11 CRK28723.1 - 0.0081 16.1 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) Abhydrolase_8 PF06259.12 CRK28723.1 - 0.034 13.8 1.3 0.049 13.3 1.3 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase MFS_1 PF07690.16 CRK28724.1 - 6.4e-27 94.4 29.5 9.1e-27 93.9 29.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_3_C PF01915.22 CRK28725.1 - 2.6e-60 203.9 0.0 1.2e-59 201.7 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 CRK28725.1 - 4.6e-39 134.7 0.0 4.2e-34 118.4 0.0 2.3 1 1 1 2 2 2 2 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 CRK28725.1 - 1.5e-19 69.9 0.5 5.4e-19 68.1 0.1 2.1 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.12 CRK28725.1 - 0.00045 20.1 0.0 0.0011 18.8 0.0 1.6 1 0 0 1 1 1 1 PA14 domain Beta-lactamase PF00144.24 CRK28726.1 - 2.5e-31 109.2 0.0 4e-31 108.5 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Sugar_tr PF00083.24 CRK28727.1 - 2.9e-64 217.6 15.7 3.7e-64 217.3 15.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK28727.1 - 1.1e-20 73.9 29.6 2.5e-20 72.7 22.9 2.7 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.6 CRK28727.1 - 8.6e-08 31.2 18.7 3.8e-07 29.0 5.1 3.3 2 1 1 3 3 3 2 MFS/sugar transport protein DUF872 PF05915.12 CRK28727.1 - 0.003 17.7 0.1 0.023 14.8 0.0 2.4 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF872) MFS_1_like PF12832.7 CRK28727.1 - 0.6 8.9 11.9 0.52 9.1 6.0 2.6 1 1 0 2 2 2 0 MFS_1 like family Ferric_reduct PF01794.19 CRK28728.1 - 6.2e-18 65.1 13.6 6.2e-18 65.1 13.6 2.5 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 CRK28728.1 - 1e-05 25.6 0.0 2.6e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 CRK28728.1 - 0.0042 17.2 0.0 1.3 9.2 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain DUF1749 PF08538.10 CRK28729.1 - 1.5e-74 250.8 0.0 1.8e-74 250.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Hydrolase_4 PF12146.8 CRK28729.1 - 0.0012 18.2 0.0 0.0077 15.5 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 CBM_1 PF00734.18 CRK28730.1 - 5.2e-12 45.5 18.1 1.6e-11 44.0 18.1 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain Sortilin-Vps10 PF15902.5 CRK28730.1 - 1.2e-11 44.1 5.5 0.0047 15.8 0.0 4.4 3 2 2 5 5 5 5 Sortilin, neurotensin receptor 3, BNR PF02012.20 CRK28730.1 - 0.03 14.3 40.9 0.18 11.9 0.0 9.7 9 0 0 9 9 9 0 BNR/Asp-box repeat Toxin_7 PF05980.12 CRK28730.1 - 0.066 13.5 3.2 0.11 12.7 3.2 1.3 1 0 0 1 1 1 0 Toxin 7 Kelch_1 PF01344.25 CRK28730.1 - 0.073 12.7 0.2 0.34 10.5 0.2 2.3 1 0 0 1 1 1 0 Kelch motif BNR_2 PF13088.6 CRK28730.1 - 3.7 6.8 9.8 6.4 6.0 0.2 4.0 3 1 2 5 5 5 0 BNR repeat-like domain dCMP_cyt_deam_1 PF00383.23 CRK28731.1 - 2e-13 50.1 0.1 3e-13 49.5 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CRK28731.1 - 8.2e-08 32.1 0.0 1.1e-06 28.4 0.0 2.1 1 1 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 CRK28731.1 - 0.034 14.2 1.6 0.097 12.7 1.6 1.6 1 1 0 1 1 1 0 Bd3614-like deaminase Glyco_hydro_53 PF07745.13 CRK28732.1 - 5.1e-99 331.5 0.0 5.7e-99 331.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Lactamase_B PF00753.27 CRK28733.1 - 9.4e-17 61.7 0.5 1.6e-16 60.9 0.5 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CRK28733.1 - 4.7e-05 23.0 0.0 8.2e-05 22.2 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain p450 PF00067.22 CRK28734.1 - 3.8e-48 164.4 0.0 8.2e-48 163.3 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 ABC_tran PF00005.27 CRK28735.1 - 7e-50 169.1 0.6 8e-27 94.4 0.0 2.8 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.23 CRK28735.1 - 3.2e-33 115.6 29.9 9.7e-19 68.1 5.4 4.2 3 1 1 4 4 4 2 ABC transporter transmembrane region MMR_HSR1 PF01926.23 CRK28735.1 - 7.6e-07 29.2 0.5 0.033 14.3 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 CRK28735.1 - 7.6e-06 26.4 0.1 0.043 14.2 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 CRK28735.1 - 6e-05 22.7 1.6 0.34 10.7 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CRK28735.1 - 6.6e-05 22.9 1.1 0.047 13.6 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase SMC_N PF02463.19 CRK28735.1 - 0.00021 20.8 1.5 2 7.8 0.1 4.1 2 2 0 4 4 4 1 RecF/RecN/SMC N terminal domain NB-ARC PF00931.22 CRK28735.1 - 0.00025 20.3 0.5 0.21 10.7 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain AAA_21 PF13304.6 CRK28735.1 - 0.00038 20.4 2.6 0.8 9.4 0.1 3.6 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 CRK28735.1 - 0.00048 20.4 1.0 1.4 9.2 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.6 CRK28735.1 - 0.0012 19.4 0.2 0.77 10.2 0.4 2.5 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 CRK28735.1 - 0.0028 17.7 1.8 0.21 11.7 0.3 2.6 2 0 0 2 2 2 1 Dynamin family DUF87 PF01935.17 CRK28735.1 - 0.0038 17.3 2.4 0.17 11.9 0.5 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain MeaB PF03308.16 CRK28735.1 - 0.0051 15.8 0.1 0.23 10.4 0.1 2.3 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Zeta_toxin PF06414.12 CRK28735.1 - 0.0063 15.8 0.3 1.1 8.5 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin AAA_7 PF12775.7 CRK28735.1 - 0.0091 15.5 0.5 1.5 8.3 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_30 PF13604.6 CRK28735.1 - 0.011 15.4 1.9 1.4 8.6 0.1 2.8 3 0 0 3 3 2 0 AAA domain AAA_25 PF13481.6 CRK28735.1 - 0.024 14.2 0.0 2.4 7.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 CRK28735.1 - 0.043 13.5 0.3 0.69 9.6 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain NACHT PF05729.12 CRK28735.1 - 0.044 13.7 0.2 1.8 8.5 0.0 2.5 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.22 CRK28735.1 - 0.054 13.9 0.2 2.9 8.3 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.6 CRK28735.1 - 0.074 13.6 0.5 24 5.5 0.3 2.7 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 CRK28735.1 - 0.093 13.0 1.1 1.3 9.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.7 CRK28735.1 - 0.11 11.5 0.6 1.2 8.0 0.1 2.2 2 0 0 2 2 2 0 AAA-like domain FtsK_SpoIIIE PF01580.18 CRK28735.1 - 0.14 11.5 0.1 1.8 7.8 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family ATP-synt_ab PF00006.25 CRK28735.1 - 0.14 11.8 0.3 1.4 8.5 0.1 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain cobW PF02492.19 CRK28735.1 - 0.62 9.6 3.6 16 5.0 0.1 2.8 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Ferric_reduct PF01794.19 CRK28736.1 - 1.6e-20 73.5 11.6 5.1e-20 71.9 11.6 1.9 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAS PF03059.16 CRK28736.1 - 2.2e-17 63.3 0.0 3.9e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 Nicotianamine synthase protein NAD_binding_6 PF08030.12 CRK28736.1 - 1.1e-15 58.1 0.0 2.2e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain ATPgrasp_N PF18130.1 CRK28736.1 - 2.4e-13 50.4 0.0 6.1e-13 49.1 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp N-terminal domain ATP-grasp_4 PF13535.6 CRK28736.1 - 3.1e-11 43.1 0.0 7.6e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain FAD_binding_8 PF08022.12 CRK28736.1 - 7.9e-06 25.9 0.3 4e-05 23.7 0.3 2.1 1 1 0 1 1 1 1 FAD-binding domain Dala_Dala_lig_C PF07478.13 CRK28736.1 - 9.3e-05 22.0 0.0 0.00032 20.3 0.0 1.8 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.17 CRK28736.1 - 0.0016 17.9 0.0 0.0032 17.0 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain NAD_binding_1 PF00175.21 CRK28736.1 - 0.0019 18.8 0.0 0.0055 17.3 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Methyltransf_25 PF13649.6 CRK28736.1 - 0.0022 18.6 0.0 0.0058 17.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ATP-grasp_3 PF02655.14 CRK28736.1 - 0.051 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain AP_endonuc_2 PF01261.24 CRK28736.1 - 0.1 12.0 0.0 1.4 8.3 0.0 2.3 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel Methyltransf_11 PF08241.12 CRK28736.1 - 0.18 12.5 0.0 0.48 11.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Cys_Met_Meta_PP PF01053.20 CRK28737.1 - 5.8e-107 357.5 0.0 7.1e-106 353.9 0.0 1.9 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 CRK28737.1 - 3.7e-10 39.5 0.0 5.5e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 CRK28737.1 - 1.5e-08 34.0 0.1 2.3e-08 33.4 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 CRK28737.1 - 1.6e-07 31.0 0.2 2.9e-07 30.1 0.2 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 CRK28737.1 - 0.002 17.4 0.0 0.0029 16.9 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase GDC-P PF02347.16 CRK28737.1 - 0.024 13.5 0.0 0.033 13.0 0.0 1.1 1 0 0 1 1 1 0 Glycine cleavage system P-protein ADH_zinc_N PF00107.26 CRK28737.1 - 0.077 13.0 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 Zinc-binding dehydrogenase p450 PF00067.22 CRK28738.1 - 0.017 13.9 0.0 0.023 13.4 0.0 1.2 1 0 0 1 1 1 0 Cytochrome P450 Caveolin PF01146.17 CRK28738.1 - 0.097 12.6 1.7 0.15 12.0 1.7 1.2 1 0 0 1 1 1 0 Caveolin Peptidase_M14 PF00246.24 CRK28739.1 - 7.8e-30 104.7 0.6 9.9e-30 104.3 0.6 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase SRP54 PF00448.22 CRK28740.1 - 1.5e-76 256.4 3.0 5.3e-76 254.6 1.7 2.1 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 CRK28740.1 - 5.5e-31 107.1 5.9 5.5e-31 107.1 5.9 4.1 3 1 1 4 4 3 1 Signal peptide binding domain SRP54_N PF02881.19 CRK28740.1 - 3.2e-20 72.1 0.2 7.7e-20 70.9 0.2 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 CRK28740.1 - 9.5e-07 28.6 1.2 5.9e-06 26.0 1.0 2.3 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 CRK28740.1 - 1e-06 29.0 0.0 2.5e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 CRK28740.1 - 4.8e-05 23.8 0.1 4.8e-05 23.8 0.1 2.4 3 0 0 3 3 1 1 AAA domain MeaB PF03308.16 CRK28740.1 - 0.0001 21.4 0.9 0.0011 18.1 0.9 2.6 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 CRK28740.1 - 0.00038 20.9 0.0 0.00081 19.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 CRK28740.1 - 0.0007 19.4 0.1 0.0028 17.4 0.1 2.1 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 CRK28740.1 - 0.00071 18.9 0.0 0.0015 17.8 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin APS_kinase PF01583.20 CRK28740.1 - 0.0018 18.2 0.0 0.0037 17.2 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase Thymidylate_kin PF02223.17 CRK28740.1 - 0.0021 17.8 0.8 0.0069 16.1 0.1 2.2 2 0 0 2 2 2 1 Thymidylate kinase CbiA PF01656.23 CRK28740.1 - 0.0032 17.5 0.0 0.0086 16.1 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_18 PF13238.6 CRK28740.1 - 0.0052 17.3 0.0 0.013 16.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CRK28740.1 - 0.0054 17.0 0.0 0.015 15.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 CRK28740.1 - 0.0075 16.3 0.1 0.035 14.2 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 CRK28740.1 - 0.0083 15.9 0.2 0.039 13.7 0.1 2.2 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein ResIII PF04851.15 CRK28740.1 - 0.0092 16.0 0.7 0.042 13.8 0.7 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit MobB PF03205.14 CRK28740.1 - 0.01 15.7 0.0 0.028 14.3 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B SRPRB PF09439.10 CRK28740.1 - 0.013 14.9 0.6 3 7.2 0.1 3.1 2 1 0 3 3 3 0 Signal recognition particle receptor beta subunit AAA_19 PF13245.6 CRK28740.1 - 0.023 15.0 0.1 0.053 13.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 CRK28740.1 - 0.027 14.7 0.0 0.05 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF1611 PF07755.11 CRK28740.1 - 0.043 13.1 0.1 0.099 11.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1611_C) P-loop domain 6PF2K PF01591.18 CRK28740.1 - 0.052 12.9 0.0 0.085 12.1 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase DUF3052 PF11253.8 CRK28740.1 - 0.084 12.8 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3052) AAA_24 PF13479.6 CRK28740.1 - 0.085 12.6 0.2 0.24 11.1 0.0 2.0 2 0 0 2 2 1 0 AAA domain Torsin PF06309.11 CRK28740.1 - 0.086 12.9 0.0 0.23 11.6 0.0 1.6 1 1 0 1 1 1 0 Torsin AAA PF00004.29 CRK28740.1 - 0.11 13.0 0.2 0.34 11.3 0.2 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Arf PF00025.21 CRK28740.1 - 0.12 11.8 0.0 0.43 10.0 0.0 1.9 1 0 0 1 1 1 0 ADP-ribosylation factor family Repressor_Mnt PF11423.8 CRK28740.1 - 0.17 11.7 0.8 0.72 9.7 0.5 2.3 1 1 0 1 1 1 0 Regulatory protein Mnt SKA2 PF16740.5 CRK28740.1 - 0.37 10.6 5.7 11 5.8 1.9 2.6 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Cation_ATPase_N PF00690.26 CRK28741.1 - 4.5e-18 64.7 0.2 5.8e-18 64.3 0.2 1.1 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus EMC3_TMCO1 PF01956.16 CRK28741.1 - 0.0087 15.8 0.1 0.0091 15.7 0.1 1.0 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like Oxidored_FMN PF00724.20 CRK28743.1 - 6.7e-86 288.7 0.0 1.1e-85 288.0 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Sec31 PF11549.8 CRK28743.1 - 0.098 12.6 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein transport protein SEC31 DIOX_N PF14226.6 CRK28745.1 - 3.7e-24 85.7 0.0 6.9e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 CRK28745.1 - 1.7e-19 70.1 0.0 4.1e-19 68.9 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Rieske PF00355.26 CRK28745.1 - 7.4e-08 32.2 0.0 1.7e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 CRK28745.1 - 4.5e-05 23.3 0.0 8.8e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain PLU-1 PF08429.11 CRK28746.1 - 4e-113 378.0 12.1 9e-110 367.0 10.4 2.2 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.22 CRK28746.1 - 8.9e-43 145.3 0.2 1.9e-42 144.3 0.2 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.21 CRK28746.1 - 4e-21 75.5 0.1 1.1e-20 74.1 0.1 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.17 CRK28746.1 - 2.3e-14 53.0 1.9 7.1e-14 51.5 1.9 1.9 1 0 0 1 1 1 1 jmjN domain PHD PF00628.29 CRK28746.1 - 4.6e-08 32.8 9.0 1.4e-07 31.3 9.0 1.9 1 0 0 1 1 1 1 PHD-finger KIX PF02172.16 CRK28746.1 - 0.03 14.6 0.0 0.11 12.8 0.0 1.9 1 0 0 1 1 1 0 KIX domain zf-HC5HC2H PF13771.6 CRK28746.1 - 0.033 14.4 2.3 0.083 13.1 2.3 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain PHD_4 PF16866.5 CRK28746.1 - 0.34 11.0 5.1 0.88 9.7 5.1 1.7 1 0 0 1 1 1 0 PHD-finger C1_1 PF00130.22 CRK28746.1 - 0.53 10.2 3.9 1.4 8.9 3.9 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zf_RING PF16744.5 CRK28746.1 - 1.7 8.9 6.6 2.9 8.1 5.3 2.1 1 1 0 1 1 1 0 KIAA1045 RING finger GIY-YIG PF01541.24 CRK28747.1 - 3.7e-13 49.6 0.0 6.8e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain zf-HC5HC2H_2 PF13832.6 CRK28747.1 - 0.00012 22.2 2.9 0.00091 19.4 1.8 2.3 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 CRK28747.1 - 0.001 19.3 4.2 0.0027 17.9 2.4 2.2 2 0 0 2 2 2 1 PHD-like zinc-binding domain FANCL_C PF11793.8 CRK28747.1 - 0.0016 18.6 4.3 0.0054 16.9 3.0 2.2 2 0 0 2 2 2 1 FANCL C-terminal domain DUF2685 PF10886.8 CRK28747.1 - 0.005 17.0 3.5 2.1 8.6 0.1 2.9 4 0 0 4 4 4 2 Protein of unknown function (DUF2685) C1_1 PF00130.22 CRK28747.1 - 0.019 14.8 2.2 1.7 8.6 0.9 2.7 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF1442 PF07279.11 CRK28747.1 - 0.053 12.8 0.0 8.6 5.6 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1442) T5orf172 PF10544.9 CRK28747.1 - 0.12 12.9 0.0 0.23 12.0 0.0 1.5 1 0 0 1 1 1 0 T5orf172 domain Prok-RING_1 PF14446.6 CRK28747.1 - 0.17 11.8 8.8 0.11 12.5 1.0 3.3 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-RING_2 PF13639.6 CRK28747.1 - 0.64 10.4 8.8 1.7 9.0 7.3 2.1 2 0 0 2 2 2 0 Ring finger domain Rhodanese_C PF12368.8 CRK28747.1 - 9.1 6.7 8.5 62 4.1 5.1 3.4 4 1 1 5 5 5 0 Rhodanase C-terminal DEAD PF00270.29 CRK28748.1 - 1.2e-13 51.2 0.4 1.9e-13 50.6 0.4 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CRK28748.1 - 0.0018 18.3 0.0 0.017 15.1 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 CRK28748.1 - 0.0087 15.8 0.4 0.013 15.2 0.4 1.2 1 0 0 1 1 1 1 AAA domain DUF5393 PF17371.2 CRK28748.1 - 0.051 11.7 2.2 0.098 10.8 0.4 1.8 1 1 1 2 2 2 0 Family of unknown function (DUF5393) AAA_19 PF13245.6 CRK28748.1 - 0.085 13.2 0.9 0.11 12.8 0.2 1.5 2 0 0 2 2 2 0 AAA domain DUF3449 PF11931.8 CRK28749.1 - 1.3e-68 230.4 0.2 1.9e-68 229.9 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3449) GIY-YIG PF01541.24 CRK28749.1 - 3.4e-21 75.3 0.0 4.6e-13 49.3 0.0 2.5 2 0 0 2 2 2 2 GIY-YIG catalytic domain T5orf172 PF10544.9 CRK28749.1 - 2.6e-05 24.7 0.0 0.16 12.5 0.0 2.5 2 0 0 2 2 2 2 T5orf172 domain DUF4820 PF16091.5 CRK28749.1 - 0.48 9.8 2.3 6.9 6.0 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4820) DEAD PF00270.29 CRK28750.1 - 9.6e-42 142.7 0.1 1.6e-41 142.0 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CRK28750.1 - 2.6e-33 114.7 0.0 9.7e-33 112.8 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 CRK28750.1 - 0.00055 19.7 0.1 0.00082 19.1 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CRK28750.1 - 0.0014 19.0 0.0 0.012 16.0 0.1 2.2 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 CRK28750.1 - 0.0016 18.4 0.0 0.0032 17.5 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF5393 PF17371.2 CRK28750.1 - 0.053 11.7 0.1 0.084 11.0 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5393) Flavi_DEAD PF07652.14 CRK28750.1 - 0.066 13.2 0.2 0.23 11.4 0.0 2.0 2 1 0 2 2 2 0 Flavivirus DEAD domain TniB PF05621.11 CRK28750.1 - 0.068 12.6 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein Helicase_RecD PF05127.14 CRK28750.1 - 0.077 12.8 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Helicase AAA_22 PF13401.6 CRK28750.1 - 0.17 12.2 1.1 0.77 10.0 1.1 2.0 1 1 0 1 1 1 0 AAA domain TauD PF02668.16 CRK28751.1 - 4.6e-28 98.8 0.8 1.2e-27 97.4 0.8 1.6 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DAG1 PF05454.11 CRK28751.1 - 0.32 10.3 0.0 0.32 10.3 0.0 1.6 2 0 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Sdh_cyt PF01127.22 CRK28752.1 - 4.9e-17 62.1 4.0 6.3e-17 61.7 4.0 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit TAF6_C PF07571.13 CRK28753.1 - 2.5e-28 98.2 0.0 6e-28 97.0 0.0 1.7 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 CRK28753.1 - 4.6e-21 74.7 0.1 9.8e-21 73.7 0.1 1.6 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.13 CRK28753.1 - 0.002 18.1 0.0 0.0041 17.1 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.24 CRK28753.1 - 0.0094 16.3 0.2 0.015 15.7 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CRK28753.1 - 0.16 12.3 0.0 0.35 11.2 0.0 1.6 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone FAD_binding_3 PF01494.19 CRK28754.1 - 1.7e-07 30.9 1.2 2.3e-07 30.4 1.2 1.2 1 0 0 1 1 1 1 FAD binding domain CsbD PF05532.12 CRK28754.1 - 0.00035 20.4 2.9 0.0044 16.9 0.1 2.6 1 1 1 2 2 2 1 CsbD-like BCL_N PF04714.13 CRK28754.1 - 0.4 10.8 2.7 3 8.0 0.1 2.4 2 0 0 2 2 2 0 BCL7, N-terminal conserver region Sugar_tr PF00083.24 CRK28756.1 - 4e-96 322.6 20.3 5.1e-96 322.3 20.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK28756.1 - 8.7e-20 70.9 34.7 1.4e-19 70.3 30.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_3_2 PF04550.12 CRK28756.1 - 0.6 10.7 3.4 0.37 11.3 0.6 2.2 2 0 0 2 2 2 0 Phage holin family 2 DJ-1_PfpI PF01965.24 CRK28757.1 - 3e-12 46.6 0.0 6e-12 45.7 0.0 1.6 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 CRK28757.1 - 5.9e-07 29.4 0.0 2.6e-06 27.3 0.0 1.9 1 1 0 1 1 1 1 ThiJ/PfpI family-like Zn_clus PF00172.18 CRK28758.1 - 1.4e-06 28.3 7.9 2.6e-06 27.5 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RPE65 PF03055.15 CRK28759.1 - 1.9e-104 350.5 0.0 2.2e-104 350.3 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Sugar_tr PF00083.24 CRK28760.1 - 1.9e-73 247.9 19.4 3.2e-73 247.1 19.4 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK28760.1 - 1.7e-27 96.3 24.6 6.8e-26 91.0 17.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 CRK28760.1 - 1.5e-05 24.5 0.6 1.5e-05 24.5 0.6 1.7 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB YrhK PF14145.6 CRK28760.1 - 0.0026 17.6 4.0 0.0036 17.1 0.6 2.9 2 0 0 2 2 2 1 YrhK-like protein Gtr1_RagA PF04670.12 CRK28761.1 - 1.8e-92 308.9 0.0 2.3e-92 308.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 CRK28761.1 - 9.2e-08 32.3 0.0 1.7e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CRK28761.1 - 1.2e-07 31.5 0.0 2.1e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 CRK28761.1 - 2.7e-07 30.7 0.0 4.6e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 CRK28761.1 - 2.7e-07 30.2 0.1 4.1e-07 29.6 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 CRK28761.1 - 0.0015 17.8 3.9 0.38 9.9 0.7 2.8 2 1 1 3 3 3 2 G-protein alpha subunit AAA_29 PF13555.6 CRK28761.1 - 0.0028 17.4 0.7 0.038 13.7 0.2 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF815 PF05673.13 CRK28761.1 - 0.0034 16.6 0.2 0.0079 15.4 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ABC_tran PF00005.27 CRK28761.1 - 0.0063 17.0 0.1 0.012 16.2 0.1 1.6 1 1 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 CRK28761.1 - 0.011 15.7 0.1 0.25 11.2 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase AAA_7 PF12775.7 CRK28761.1 - 0.11 12.0 0.1 0.55 9.7 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 CRK28761.1 - 0.15 11.7 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain SEP PF08059.13 CRK28762.1 - 3e-24 85.4 0.0 3.7e-23 81.9 0.0 2.4 2 0 0 2 2 2 1 SEP domain UBX PF00789.20 CRK28762.1 - 3.7e-09 36.6 0.0 6.4e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 CRK28762.1 - 8e-09 35.2 0.7 1.3e-08 34.5 0.7 1.4 1 0 0 1 1 1 1 UBA-like domain TAP_C PF03943.13 CRK28762.1 - 0.0015 18.1 0.0 0.0025 17.4 0.0 1.3 1 0 0 1 1 1 1 TAP C-terminal domain SWIRM-assoc_2 PF16496.5 CRK28762.1 - 0.21 10.4 0.7 0.3 9.9 0.7 1.2 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal TOM13 PF08219.11 CRK28763.1 - 9.7e-38 128.0 0.0 1.3e-37 127.6 0.0 1.1 1 0 0 1 1 1 1 Outer membrane protein TOM13 60KD_IMP PF02096.20 CRK28764.1 - 5.8e-18 65.3 10.7 2.2e-14 53.7 5.1 2.2 2 0 0 2 2 2 2 60Kd inner membrane protein DUF1688 PF07958.11 CRK28766.1 - 1.5e-180 600.4 0.0 1.8e-180 600.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) LacAB_rpiB PF02502.18 CRK28767.1 - 6.9e-44 149.2 0.1 7.8e-44 149.0 0.1 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase MTES_1575 PF18741.1 CRK28767.1 - 0.14 12.3 0.0 0.97 9.6 0.0 2.2 2 1 0 2 2 2 0 REase_MTES_1575 TIM PF00121.18 CRK28768.1 - 7.4e-48 163.0 0.0 1.2e-47 162.4 0.0 1.3 1 0 0 1 1 1 1 Triosephosphate isomerase DUF1308 PF07000.11 CRK28768.1 - 5.5e-05 23.1 0.0 0.00027 20.9 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1308) Ferritin PF00210.24 CRK28768.1 - 7.1e-05 22.8 0.0 0.23 11.4 0.0 2.3 2 0 0 2 2 2 2 Ferritin-like domain DUF5614 PF18474.1 CRK28768.1 - 0.0061 15.9 0.1 0.012 14.9 0.1 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5614) D-ser_dehydrat PF14031.6 CRK28769.1 - 1.3e-21 77.0 0.0 3.2e-21 75.8 0.0 1.7 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 CRK28769.1 - 2.5e-14 53.5 0.1 3.9e-14 52.8 0.1 1.3 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Lambda_CIII PF02061.16 CRK28769.1 - 0.037 14.1 0.7 0.17 12.0 0.0 2.4 3 0 0 3 3 3 0 Lambda Phage CIII Pkinase PF00069.25 CRK28770.1 - 8.4e-16 58.1 0.0 3.8e-15 56.0 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK28770.1 - 4.8e-08 32.6 0.0 3.7e-07 29.7 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase CorA PF01544.18 CRK28773.1 - 0.044 13.1 13.7 0.042 13.2 5.2 2.8 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein EMP70 PF02990.16 CRK28773.1 - 0.15 10.7 3.5 0.18 10.5 1.7 1.7 2 0 0 2 2 2 0 Endomembrane protein 70 Pkinase PF00069.25 CRK28774.1 - 8.5e-17 61.4 0.0 1.6e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK28774.1 - 2.4e-06 27.0 0.0 4.2e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase SBBP PF06739.11 CRK28775.1 - 0.15 12.1 0.0 0.59 10.2 0.0 2.0 1 0 0 1 1 1 0 Beta-propeller repeat p450 PF00067.22 CRK28776.1 - 2.4e-51 174.9 0.0 3.7e-51 174.3 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Tim17 PF02466.19 CRK28777.1 - 0.033 14.6 0.2 0.17 12.3 0.1 2.2 2 0 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family PEP_mutase PF13714.6 CRK28778.1 - 4.7e-65 219.4 0.4 5.4e-65 219.2 0.4 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase CAP PF00188.26 CRK28779.1 - 1.7e-19 70.9 0.7 2.6e-19 70.3 0.7 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family p450 PF00067.22 CRK28781.1 - 7.8e-24 84.2 0.0 1.8e-15 56.6 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 YcaO_C PF18381.1 CRK28781.1 - 0.21 11.5 0.0 0.39 10.6 0.0 1.3 1 0 0 1 1 1 0 YcaO cyclodehydratase C-terminal domain FAD_binding_4 PF01565.23 CRK28782.1 - 2.5e-21 75.9 2.8 4.3e-21 75.1 2.8 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 CRK28782.1 - 2.1e-07 30.9 0.4 4.1e-07 30.0 0.4 1.5 1 0 0 1 1 1 1 Berberine and berberine like HET PF06985.11 CRK28783.1 - 5e-32 111.3 2.6 7.9e-32 110.6 2.6 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NUDIX PF00293.28 CRK28783.1 - 8.9e-07 29.0 0.0 1.9e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain Peptidase_M56 PF05569.11 CRK28784.1 - 0.032 13.4 8.2 0.045 12.9 8.2 1.2 1 0 0 1 1 1 0 BlaR1 peptidase M56 CorA PF01544.18 CRK28786.1 - 0.00038 19.9 0.1 0.0006 19.2 0.1 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein MFS_1 PF07690.16 CRK28787.1 - 1.7e-41 142.4 32.3 1.7e-41 142.4 32.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK28787.1 - 4.1e-13 49.0 11.0 4.1e-13 49.0 11.0 2.8 2 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 CRK28787.1 - 1.2e-05 23.9 2.5 2.1e-05 23.1 2.5 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Trypan_PARP PF05887.11 CRK28787.1 - 0.63 10.0 9.6 1.2 9.1 9.6 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Aminotran_3 PF00202.21 CRK28788.1 - 7.2e-39 133.6 0.0 5.8e-19 68.0 0.0 3.1 2 1 0 2 2 2 2 Aminotransferase class-III Fungal_trans PF04082.18 CRK28789.1 - 1.2e-51 175.3 0.1 1.8e-51 174.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aminotran_1_2 PF00155.21 CRK28789.1 - 3.2e-31 108.8 0.0 4.7e-31 108.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II zf-C2H2 PF00096.26 CRK28789.1 - 0.0019 18.5 0.2 0.0075 16.7 0.2 2.1 1 0 0 1 1 1 1 Zinc finger, C2H2 type Cys_Met_Meta_PP PF01053.20 CRK28789.1 - 0.022 13.3 0.0 0.14 10.7 0.0 1.9 1 1 1 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme DUF5326 PF17260.2 CRK28789.1 - 0.14 12.3 0.0 0.34 11.1 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5326) Ank_2 PF12796.7 CRK28790.1 - 1.3e-16 61.0 4.2 2.1e-10 41.0 1.3 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CRK28790.1 - 3e-12 46.5 1.6 6.7e-07 29.5 0.2 2.3 1 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 CRK28790.1 - 1.2e-11 44.9 0.3 7.2e-07 29.6 0.1 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CRK28790.1 - 5.6e-11 41.7 0.6 3.1e-05 24.0 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 CRK28790.1 - 2.2e-10 40.5 2.6 3.7e-06 27.1 0.3 2.5 2 0 0 2 2 2 2 Ankyrin repeat DUF3330 PF11809.8 CRK28790.1 - 0.004 17.2 0.1 0.042 13.9 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3330) DUF2399 PF09664.10 CRK28791.1 - 0.059 13.3 0.0 0.093 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2399) SGS PF05002.15 CRK28792.1 - 1.4e-27 95.6 4.0 1.4e-27 95.6 4.0 2.1 3 0 0 3 3 3 1 SGS domain CS PF04969.16 CRK28792.1 - 8e-25 87.7 0.0 5.5e-10 40.1 0.0 3.3 3 0 0 3 3 3 3 CS domain DcuA_DcuB PF03605.14 CRK28792.1 - 0.0097 14.8 2.9 1.3 7.8 0.2 2.2 2 0 0 2 2 2 2 Anaerobic c4-dicarboxylate membrane transporter MetallophosC PF16370.5 CRK28792.1 - 0.013 15.7 1.8 3.7 7.8 0.1 2.7 2 1 0 3 3 3 0 C terminal of Calcineurin-like phosphoesterase TPR_16 PF13432.6 CRK28792.1 - 0.027 15.1 6.0 0.027 15.1 6.0 5.7 4 3 3 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.17 CRK28792.1 - 0.045 13.9 8.7 0.65 10.3 0.2 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 CRK28792.1 - 0.1 13.1 7.1 1.3 9.6 0.1 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat NUMOD4 PF07463.11 CRK28792.1 - 0.19 12.0 0.0 34 4.8 0.0 2.3 2 0 0 2 2 2 0 NUMOD4 motif TPR_1 PF00515.28 CRK28792.1 - 0.26 11.2 2.1 0.81 9.6 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 CRK28792.1 - 0.43 10.9 16.8 0.17 12.2 3.5 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat Lipase_GDSL_2 PF13472.6 CRK28793.1 - 1.6e-11 45.0 1.2 2.1e-11 44.5 1.2 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 CRK28793.1 - 0.00093 19.2 0.1 0.0017 18.3 0.1 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase tRNA_int_endo PF01974.17 CRK28794.1 - 4e-19 68.5 0.0 8.7e-19 67.4 0.0 1.6 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 CRK28794.1 - 6.4e-06 25.7 0.1 0.068 12.9 0.0 2.3 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain Glyco_transf_21 PF13506.6 CRK28795.1 - 1.6e-12 47.2 0.0 0.00015 21.3 0.0 3.3 2 1 0 3 3 3 3 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 CRK28795.1 - 2e-07 31.1 0.0 5e-06 26.6 0.0 2.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 CRK28795.1 - 0.17 11.7 0.1 1 9.2 0.1 2.1 1 1 0 1 1 1 0 Glycosyl transferase family 2 Glyco_hydro_28 PF00295.17 CRK28796.1 - 2.6e-37 128.6 6.4 1e-36 126.6 4.1 2.0 1 1 1 2 2 2 2 Glycosyl hydrolases family 28 Beta_helix PF13229.6 CRK28796.1 - 0.013 15.3 5.3 0.014 15.3 3.7 1.9 1 1 0 1 1 1 0 Right handed beta helix region DAO PF01266.24 CRK28797.1 - 7.7e-31 107.9 0.1 9.2e-31 107.7 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CRK28797.1 - 0.00011 22.3 0.1 0.00035 20.7 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 CRK28797.1 - 0.00016 21.7 0.2 0.0022 18.0 0.0 2.4 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 CRK28797.1 - 0.00016 21.0 0.0 0.025 13.9 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CRK28797.1 - 0.00035 19.9 0.0 0.048 12.9 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CRK28797.1 - 0.00038 19.8 0.0 0.00061 19.1 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 CRK28797.1 - 0.00077 18.6 0.1 0.0013 17.8 0.1 1.5 1 1 0 1 1 1 1 Lycopene cyclase protein K_oxygenase PF13434.6 CRK28797.1 - 0.0019 17.4 0.0 0.0031 16.7 0.0 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 CRK28797.1 - 0.0064 15.8 0.0 0.01 15.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 CRK28797.1 - 0.011 14.9 0.2 0.059 12.4 0.2 1.9 1 1 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 CRK28797.1 - 0.021 15.4 0.0 10 6.7 0.0 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase TPR_12 PF13424.6 CRK28798.1 - 1e-11 44.9 7.9 3.5e-06 27.2 0.2 5.2 4 2 2 6 6 6 4 Tetratricopeptide repeat NACHT PF05729.12 CRK28798.1 - 5.8e-05 23.1 0.1 0.00059 19.8 0.0 2.5 2 1 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 CRK28798.1 - 0.0074 16.6 0.0 0.048 13.9 0.0 2.5 1 1 0 1 1 1 1 AAA domain TPR_19 PF14559.6 CRK28798.1 - 0.012 16.1 0.1 0.012 16.1 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC5 PF12862.7 CRK28798.1 - 0.017 15.2 0.5 0.21 11.7 0.1 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 5 TPR_11 PF13414.6 CRK28798.1 - 0.12 12.1 0.2 1.2 8.9 0.1 2.6 2 0 0 2 2 2 0 TPR repeat AAA_16 PF13191.6 CRK28798.1 - 0.26 11.7 2.5 2.5 8.5 0.0 2.9 3 0 0 3 3 3 0 AAA ATPase domain TPR_MalT PF17874.1 CRK28798.1 - 0.45 9.8 12.2 0.082 12.3 1.0 3.3 2 1 0 3 3 3 0 MalT-like TPR region Sugar_tr PF00083.24 CRK28799.1 - 0.0004 19.4 0.1 0.00058 18.8 0.1 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter Sugar_tr PF00083.24 CRK28801.1 - 8.3e-54 183.1 9.5 1e-53 182.8 9.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK28801.1 - 1.5e-13 50.4 13.5 1.8e-13 50.1 13.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 CRK28801.1 - 0.079 11.8 6.5 0.12 11.2 6.5 1.3 1 0 0 1 1 1 0 MFS_1 like family Fungal_trans PF04082.18 CRK28802.1 - 5.3e-12 45.3 0.1 7.7e-12 44.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK28802.1 - 0.0004 20.4 11.8 0.00072 19.6 11.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF5605 PF18310.1 CRK28802.1 - 0.12 12.3 0.5 0.25 11.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5605) Glyco_hydro_61 PF03443.14 CRK28803.1 - 2e-61 207.5 0.0 2.3e-61 207.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 ECH_1 PF00378.20 CRK28804.1 - 1.8e-105 351.7 0.0 2.3e-60 204.0 0.0 2.0 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CRK28804.1 - 1.8e-44 152.6 5.1 1.1e-28 100.7 0.4 3.3 2 2 2 4 4 4 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 CRK28804.1 - 0.00041 20.3 0.0 1.4 8.8 0.0 2.5 2 0 0 2 2 2 2 Peptidase family S49 CbbQ_C PF08406.10 CRK28804.1 - 0.097 12.9 0.9 17 5.7 0.1 2.5 2 0 0 2 2 2 0 CbbQ/NirQ/NorQ C-terminal DUF4520 PF15016.6 CRK28804.1 - 0.14 12.3 0.0 29 4.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4520) AMP-binding PF00501.28 CRK28805.1 - 7.9e-20 70.8 0.0 8.6e-20 70.7 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.28 CRK28806.1 - 6.6e-118 394.0 0.6 1e-77 261.5 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 CRK28806.1 - 1.4e-11 45.2 0.0 0.00043 21.2 0.0 2.6 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain JAKMIP_CC3 PF16034.5 CRK28806.1 - 0.32 10.9 0.1 34 4.3 0.0 2.3 2 0 0 2 2 2 0 JAKMIP CC3 domain DUF2650 PF10853.8 CRK28806.1 - 3.1 7.6 4.7 30 4.4 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2650) BacteriocIIc_cy PF12173.8 CRK28806.1 - 3.4 8.0 8.6 17 5.8 0.5 3.1 3 0 0 3 3 3 0 Bacteriocin class IIc cyclic gassericin A-like Galactosyl_T PF01762.21 CRK28808.1 - 0.064 13.1 0.1 0.46 10.3 0.1 2.0 1 1 0 1 1 1 0 Galactosyltransferase p450 PF00067.22 CRK28809.1 - 3.1e-47 161.4 0.0 3.6e-47 161.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 CRK28810.1 - 1.1e-40 139.8 0.0 1.4e-40 139.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Alpha-amylase PF00128.24 CRK28812.1 - 0.00026 20.6 0.0 0.00041 20.0 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1939 PF09154.10 CRK28813.1 - 0.06 13.5 0.1 0.096 12.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1939) bZIP_1 PF00170.21 CRK28814.1 - 7.8e-09 35.5 10.1 1.8e-08 34.3 10.1 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CRK28814.1 - 0.012 15.6 9.6 0.012 15.6 9.6 2.1 2 0 0 2 2 2 0 Basic region leucine zipper DivIC PF04977.15 CRK28814.1 - 8.5 6.2 11.1 1.4 8.7 0.8 2.6 2 0 0 2 2 2 0 Septum formation initiator Alpha-amylase PF00128.24 CRK28815.1 - 2.8e-22 79.7 4.1 7.9e-22 78.2 4.1 1.6 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.16 CRK28815.1 - 3.5e-05 22.2 0.2 0.36 8.9 0.0 2.9 3 0 0 3 3 3 2 Glycosyl hydrolase family 70 DUF1939 PF09154.10 CRK28815.1 - 0.12 12.6 0.3 0.54 10.5 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1939) Hydrolase_6 PF13344.6 CRK28816.1 - 1.5e-26 92.4 0.0 3.4e-26 91.3 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CRK28816.1 - 6.8e-14 51.7 0.1 1.5e-13 50.6 0.1 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like bZIP_1 PF00170.21 CRK28816.1 - 1.3e-08 34.8 10.1 3.1e-08 33.6 10.1 1.7 1 0 0 1 1 1 1 bZIP transcription factor Hydrolase PF00702.26 CRK28816.1 - 9.6e-08 32.6 0.0 2.7e-07 31.1 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CRK28816.1 - 0.00046 20.3 0.0 0.17 12.0 0.0 2.6 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase DUF4149 PF13664.6 CRK28818.1 - 2.7e-24 85.4 4.0 3.9e-24 84.9 2.9 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) DUF5510 PF17629.2 CRK28818.1 - 0.21 11.5 1.0 0.46 10.4 0.2 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5510) Toprim PF01751.22 CRK28819.1 - 6.3e-19 68.1 0.0 8.8e-19 67.6 0.0 1.2 1 0 0 1 1 1 1 Toprim domain Topoisom_bac PF01131.20 CRK28819.1 - 3.2e-18 65.9 0.0 4.5e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Pkinase PF00069.25 CRK28820.1 - 7e-19 68.2 0.0 1.3e-09 37.9 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CRK28820.1 - 0.00063 19.1 0.0 0.52 9.5 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase WaaY PF06176.11 CRK28820.1 - 0.0044 16.7 0.0 0.0074 15.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Kinase-like PF14531.6 CRK28820.1 - 0.046 13.0 0.0 0.12 11.6 0.0 1.6 2 0 0 2 2 2 0 Kinase-like Pectate_lyase PF03211.13 CRK28821.1 - 5.4e-63 212.2 2.3 6.6e-63 211.9 2.3 1.1 1 0 0 1 1 1 1 Pectate lyase Ku_PK_bind PF08785.11 CRK28822.1 - 1e-36 125.7 0.0 2.7e-36 124.3 0.0 1.8 1 0 0 1 1 1 1 Ku C terminal domain like Ku PF02735.16 CRK28822.1 - 6.4e-30 104.4 0.0 1.3e-29 103.3 0.0 1.5 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 CRK28822.1 - 2.9e-12 46.8 0.0 4.7e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain VWA PF00092.28 CRK28822.1 - 0.00026 21.3 0.0 0.00046 20.5 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Ribosomal_L24e PF01246.20 CRK28825.1 - 1.1e-29 102.5 6.4 2.5e-29 101.3 6.4 1.6 1 0 0 1 1 1 1 Ribosomal protein L24e DUF5078 PF16877.5 CRK28825.1 - 0.052 14.0 0.3 0.09 13.2 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5078) DUF3602 PF12223.8 CRK28826.1 - 1.2e-13 51.4 12.3 0.0001 22.8 1.2 3.2 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) HABP4_PAI-RBP1 PF04774.15 CRK28826.1 - 0.6 11.0 12.5 0.48 11.3 3.0 2.4 1 1 2 3 3 3 0 Hyaluronan / mRNA binding family MA3 PF02847.17 CRK28827.1 - 7.9e-22 77.4 0.0 1.6e-21 76.4 0.0 1.6 1 0 0 1 1 1 1 MA3 domain ING PF12998.7 CRK28827.1 - 0.036 14.7 0.0 0.094 13.3 0.0 1.8 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding zf-C2H2 PF00096.26 CRK28827.1 - 0.085 13.3 3.3 0.3 11.6 3.3 2.1 1 0 0 1 1 1 0 Zinc finger, C2H2 type RXT2_N PF08595.11 CRK28827.1 - 6.7 6.7 15.6 0.34 10.9 0.2 3.1 3 0 0 3 3 3 0 RXT2-like, N-terminal RRN3 PF05327.11 CRK28827.1 - 9.8 4.6 6.9 17 3.8 6.9 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Presenilin PF01080.17 CRK28840.1 - 1.2 7.9 4.3 1.9 7.2 4.3 1.3 1 0 0 1 1 1 0 Presenilin Pkinase_fungal PF17667.1 CRK28844.1 - 1.7e-135 452.0 0.0 2.4e-135 451.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 CRK28844.1 - 0.00012 21.5 0.0 0.00025 20.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 CRK28844.1 - 0.065 13.1 0.5 0.17 11.8 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family TIP49 PF06068.13 CRK28846.1 - 2.3e-128 428.3 1.3 3.9e-128 427.6 1.3 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain Dynactin PF12455.8 CRK28846.1 - 1.2e-111 372.6 8.2 1.8e-111 372.0 8.2 1.3 1 0 0 1 1 1 1 Dynein associated protein HMG_box PF00505.19 CRK28846.1 - 1.3e-17 64.0 0.2 2.5e-17 63.0 0.2 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box AAA PF00004.29 CRK28846.1 - 2.2e-08 34.6 1.0 7.2e-06 26.5 0.1 3.0 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CRK28846.1 - 6.6e-07 29.2 0.0 2e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 CRK28846.1 - 5.8e-05 23.4 1.9 0.014 15.6 0.1 2.7 2 0 0 2 2 2 2 AAA domain HMG_box_2 PF09011.10 CRK28846.1 - 0.00021 21.8 0.2 0.00044 20.8 0.2 1.5 1 0 0 1 1 1 1 HMG-box domain DnaB_C PF03796.15 CRK28846.1 - 0.009 15.4 0.6 0.12 11.7 0.0 2.3 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 CRK28846.1 - 0.054 13.9 0.1 0.054 13.9 0.1 2.8 2 1 0 2 2 2 0 AAA ATPase domain IstB_IS21 PF01695.17 CRK28846.1 - 0.058 13.1 0.2 0.21 11.3 0.2 1.9 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 CRK28846.1 - 0.06 13.9 0.0 0.18 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 CRK28846.1 - 0.11 12.8 0.4 0.46 10.8 0.4 2.0 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 CRK28846.1 - 0.13 11.6 1.3 0.21 10.8 0.1 1.9 2 0 0 2 2 2 0 Zeta toxin AAA_25 PF13481.6 CRK28846.1 - 8 6.0 8.7 0.19 11.3 0.1 2.7 4 0 0 4 4 4 0 AAA domain BRE1 PF08647.11 CRK28848.1 - 0.15 12.1 1.4 0.24 11.5 0.4 1.9 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase UPF0242 PF06785.11 CRK28848.1 - 0.16 12.1 2.5 0.24 11.5 2.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4763 PF15960.5 CRK28848.1 - 0.27 10.5 4.2 0.48 9.7 4.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) Yuri_gagarin PF15934.5 CRK28848.1 - 0.44 10.3 4.7 3.3 7.5 0.3 2.1 1 1 1 2 2 2 0 Yuri gagarin DUF2353 PF09789.9 CRK28850.1 - 7.3e-06 25.6 16.6 1e-05 25.1 16.6 1.1 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) CENP-F_leu_zip PF10473.9 CRK28850.1 - 0.063 13.3 32.5 0.04 13.9 20.1 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ZapB PF06005.12 CRK28850.1 - 0.11 12.9 35.2 0.42 11.1 11.1 3.1 2 2 1 3 3 3 0 Cell division protein ZapB DUF2730 PF10805.8 CRK28850.1 - 0.13 12.4 10.4 0.11 12.6 8.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) Syntaxin-6_N PF09177.11 CRK28850.1 - 0.16 12.6 13.5 0.041 14.4 8.2 2.4 1 1 2 3 3 3 0 Syntaxin 6, N-terminal DivIC PF04977.15 CRK28850.1 - 0.6 9.9 22.6 0.28 11.0 3.6 3.0 3 1 1 4 4 3 0 Septum formation initiator PCRF PF03462.18 CRK28850.1 - 1.8 8.4 16.5 1.7 8.5 15.3 1.7 1 1 1 2 2 2 0 PCRF domain TMF_DNA_bd PF12329.8 CRK28850.1 - 2.3 8.3 26.1 0.15 12.1 10.1 2.9 3 1 0 3 3 2 0 TATA element modulatory factor 1 DNA binding FlaC_arch PF05377.11 CRK28850.1 - 2.4 8.6 12.5 0.81 10.1 0.4 3.4 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.12 CRK28850.1 - 2.5 8.2 8.8 1.8 8.6 3.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Prominin PF05478.11 CRK28850.1 - 3.5 5.4 8.1 4.5 5.1 8.1 1.1 1 0 0 1 1 1 0 Prominin YabA PF06156.13 CRK28850.1 - 3.7 8.2 21.1 4.8 7.9 6.2 2.6 1 1 1 2 2 2 0 Initiation control protein YabA TPR_MLP1_2 PF07926.12 CRK28850.1 - 3.9 7.5 31.4 2.4 8.2 24.1 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein V_ATPase_I PF01496.19 CRK28850.1 - 3.9 5.3 14.7 4.9 5.0 14.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3818 PF12825.7 CRK28850.1 - 4 6.4 10.6 3.5 6.5 9.8 1.2 1 1 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) Fez1 PF06818.15 CRK28850.1 - 4.4 7.7 27.2 0.24 11.8 19.0 2.0 1 1 1 2 2 2 0 Fez1 DUF4337 PF14235.6 CRK28850.1 - 4.6 7.3 17.8 5.1 7.2 4.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) Spc7 PF08317.11 CRK28850.1 - 7.6 5.3 26.9 1.5 7.6 20.6 1.8 1 1 1 2 2 2 0 Spc7 kinetochore protein Seryl_tRNA_N PF02403.22 CRK28850.1 - 9.5 6.5 23.1 5.4 7.3 10.1 2.5 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF3425 PF11905.8 CRK28858.1 - 0.0079 16.2 0.0 0.0089 16.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) TPR_2 PF07719.17 CRK28859.1 - 0.00029 20.7 0.3 21 5.6 0.2 4.6 3 0 0 3 3 3 1 Tetratricopeptide repeat Hemerythrin PF01814.23 CRK28859.1 - 0.0077 16.9 1.8 4.8 7.8 0.1 2.7 2 0 0 2 2 2 2 Hemerythrin HHE cation binding domain Daxx PF03344.15 CRK28859.1 - 0.052 13.6 0.3 17 5.6 0.1 2.5 2 0 0 2 2 2 0 Daxx N-terminal Rassf1C-interacting domain TPR_12 PF13424.6 CRK28859.1 - 0.86 9.9 5.9 50 4.3 0.0 4.3 4 1 0 4 4 4 0 Tetratricopeptide repeat Syntaxin PF00804.25 CRK28859.1 - 3.9 7.1 7.2 18 4.9 0.9 2.6 2 0 0 2 2 2 0 Syntaxin CPBP PF02517.16 CRK28860.1 - 1.1e-15 57.7 7.2 1.1e-15 57.7 7.2 3.3 3 1 0 3 3 3 1 CPBP intramembrane metalloprotease Synaptobrevin PF00957.21 CRK28861.1 - 8.5 6.2 6.5 5.1 7.0 1.7 2.4 2 0 0 2 2 2 0 Synaptobrevin MMM1 PF10296.9 CRK28862.1 - 6.1e-136 452.8 0.0 2e-134 447.8 0.0 2.1 1 1 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 GIDA PF01134.22 CRK28863.1 - 7.1e-155 515.9 0.0 9.6e-155 515.5 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 CRK28863.1 - 1.9e-68 230.8 0.0 3.5e-68 229.9 0.0 1.5 1 0 0 1 1 1 1 GidA associated domain Sec1 PF00995.23 CRK28863.1 - 2.8e-41 142.4 0.1 3.8e-41 142.0 0.1 1.1 1 0 0 1 1 1 1 Sec1 family Pyr_redox_2 PF07992.14 CRK28863.1 - 8.9e-06 25.1 0.2 2.5e-05 23.6 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CRK28863.1 - 2.5e-05 23.8 3.7 4.3e-05 23.1 3.7 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CRK28863.1 - 0.00071 18.8 5.0 0.00072 18.7 3.2 1.9 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 CRK28863.1 - 0.0016 17.8 1.1 0.004 16.5 1.1 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 CRK28863.1 - 0.019 15.4 0.0 0.053 14.0 0.0 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox PF00070.27 CRK28863.1 - 0.13 12.9 0.6 0.45 11.1 0.4 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CRK28863.1 - 0.16 10.7 2.4 0.51 9.0 1.4 2.1 2 0 0 2 2 2 0 HI0933-like protein CDP-OH_P_transf PF01066.21 CRK28864.1 - 8.4e-15 55.3 1.1 8.4e-15 55.3 1.1 2.0 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase APH PF01636.23 CRK28865.1 - 1.2e-13 51.5 0.6 2e-13 50.9 0.6 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 CRK28865.1 - 0.16 11.5 0.0 0.27 10.8 0.0 1.2 1 0 0 1 1 1 0 RIO1 family SGT1 PF07093.11 CRK28869.1 - 0.064 11.7 0.1 0.097 11.1 0.1 1.1 1 0 0 1 1 1 0 SGT1 protein Dynactin_p62 PF05502.13 CRK28870.1 - 3.1e-212 705.6 0.1 4.2e-212 705.1 0.1 1.1 1 0 0 1 1 1 1 Dynactin p62 family Ribosomal_S7e PF01251.18 CRK28871.1 - 1.7e-81 272.4 0.1 2e-81 272.2 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Peptidase_M14 PF00246.24 CRK28873.1 - 5.9e-72 242.9 0.0 7e-72 242.7 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Anoctamin PF04547.12 CRK28875.1 - 3.4e-104 349.2 2.6 4.1e-104 348.9 2.6 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Uds1 PF15456.6 CRK28878.1 - 8.3e-27 93.9 7.1 8.3e-27 93.9 7.1 9.6 4 3 3 7 7 7 3 Up-regulated During Septation HR1 PF02185.16 CRK28878.1 - 0.0002 21.4 0.9 0.0002 21.4 0.9 11.4 8 2 0 9 9 9 2 Hr1 repeat Cnn_1N PF07989.11 CRK28878.1 - 0.0013 18.8 2.2 0.0013 18.8 2.2 9.7 8 2 2 10 10 10 1 Centrosomin N-terminal motif 1 betaPIX_CC PF16523.5 CRK28878.1 - 0.011 15.6 3.3 0.011 15.6 3.3 5.1 4 1 1 5 5 5 0 betaPIX coiled coil CENP-F_C_Rb_bdg PF10490.9 CRK28878.1 - 0.04 13.3 0.0 0.091 12.2 0.0 1.5 1 0 0 1 1 1 0 Rb-binding domain of kinetochore protein Cenp-F/LEK1 DUF1751 PF08551.10 CRK28879.1 - 9.2e-05 23.0 0.5 0.00017 22.1 0.5 1.5 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 CRK28879.1 - 0.00051 20.1 4.1 0.0013 18.8 4.1 1.7 1 1 0 1 1 1 1 Rhomboid family DER1 PF04511.15 CRK28879.1 - 0.16 11.9 5.6 0.14 12.1 4.2 1.6 2 0 0 2 2 2 0 Der1-like family Prenyltransf PF01255.19 CRK28881.1 - 2.4e-63 213.7 0.3 2.3e-62 210.4 0.3 1.9 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase ING PF12998.7 CRK28882.1 - 2.3e-09 37.8 0.0 0.00025 21.6 0.0 2.4 2 0 0 2 2 2 2 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 CRK28882.1 - 2.1e-06 27.5 7.6 3.4e-06 26.8 7.6 1.3 1 0 0 1 1 1 1 PHD-finger DUF3570 PF12094.8 CRK28882.1 - 0.35 9.6 3.4 0.58 8.9 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3570) zf-HC5HC2H PF13771.6 CRK28882.1 - 1.9 8.8 4.6 5.3 7.4 4.7 1.6 1 1 0 1 1 1 0 PHD-like zinc-binding domain MARVEL PF01284.23 CRK28884.1 - 1.6e-05 24.9 6.5 1.6e-05 24.9 6.5 2.2 2 0 0 2 2 2 1 Membrane-associating domain GRAB PF10375.9 CRK28885.1 - 2.2e-09 36.8 1.9 4.8e-09 35.8 0.1 2.5 3 0 0 3 3 3 1 GRIP-related Arf-binding domain Spc7 PF08317.11 CRK28885.1 - 0.00022 20.2 28.2 0.00022 20.2 28.2 1.9 1 1 0 1 1 1 1 Spc7 kinetochore protein ABC_tran_CTD PF16326.5 CRK28885.1 - 0.0023 18.1 10.2 0.0023 18.1 10.2 3.7 2 1 2 4 4 4 1 ABC transporter C-terminal domain TPR_MLP1_2 PF07926.12 CRK28885.1 - 0.0036 17.4 22.4 0.0036 17.4 22.4 3.7 1 1 2 3 3 3 1 TPR/MLP1/MLP2-like protein TolA_bind_tri PF16331.5 CRK28885.1 - 0.0062 16.6 18.2 0.026 14.6 4.8 3.7 2 2 1 3 3 3 2 TolA binding protein trimerisation HALZ PF02183.18 CRK28885.1 - 0.014 15.6 0.5 0.014 15.6 0.5 3.3 3 1 0 3 3 2 0 Homeobox associated leucine zipper UPF0242 PF06785.11 CRK28885.1 - 0.017 15.3 16.2 0.017 15.3 16.2 2.7 1 1 1 2 2 1 0 Uncharacterised protein family (UPF0242) N-terminus Filament PF00038.21 CRK28885.1 - 0.067 12.8 30.4 0.072 12.7 7.7 2.8 1 1 2 3 3 3 0 Intermediate filament protein DUF4407 PF14362.6 CRK28885.1 - 0.07 12.5 35.0 0.042 13.2 14.9 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Golgin_A5 PF09787.9 CRK28885.1 - 0.13 11.7 35.0 0.36 10.2 29.5 2.2 1 1 1 2 2 2 0 Golgin subfamily A member 5 NAPRTase_N PF17767.1 CRK28885.1 - 0.19 12.1 1.4 0.69 10.3 0.1 2.2 1 1 0 2 2 2 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain Atg14 PF10186.9 CRK28885.1 - 0.44 9.6 23.3 1.7 7.6 23.1 1.9 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 FapA PF03961.13 CRK28885.1 - 0.89 8.1 20.7 0.1 11.2 4.2 2.3 1 1 1 2 2 2 0 Flagellar Assembly Protein A Exonuc_VII_L PF02601.15 CRK28885.1 - 0.97 8.9 23.8 4.5 6.7 23.7 2.0 1 1 0 1 1 1 0 Exonuclease VII, large subunit Snapin_Pallidin PF14712.6 CRK28885.1 - 1.1 9.8 14.9 0.12 12.9 4.3 3.0 1 1 1 2 2 2 0 Snapin/Pallidin DUF1515 PF07439.11 CRK28885.1 - 1.7 8.7 10.8 5.5 7.1 1.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) KxDL PF10241.9 CRK28885.1 - 1.8 8.9 9.8 0.58 10.5 2.9 3.1 1 1 1 2 2 2 0 Uncharacterized conserved protein Glyco_hydro_67N PF03648.14 CRK28885.1 - 1.9 8.8 8.4 1.5 9.1 0.9 2.8 1 1 1 2 2 2 0 Glycosyl hydrolase family 67 N-terminus AAA_13 PF13166.6 CRK28885.1 - 3.3 6.2 31.3 1.9 7.1 14.6 2.2 1 1 1 2 2 2 0 AAA domain Lebercilin PF15619.6 CRK28885.1 - 3.6 7.2 37.4 2.3 7.8 22.4 3.6 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease DUF1664 PF07889.12 CRK28885.1 - 5.2 7.1 14.0 3.6 7.6 1.0 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 CRK28885.1 - 5.4 7.2 17.5 0.61 10.3 6.4 2.7 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family ApoO PF09769.9 CRK28885.1 - 6.7 6.7 8.4 5.2 7.0 2.5 3.2 1 1 1 2 2 2 0 Apolipoprotein O DUF745 PF05335.13 CRK28885.1 - 6.9 6.3 33.3 4.5 6.9 17.0 2.8 1 1 0 2 2 2 0 Protein of unknown function (DUF745) IFT57 PF10498.9 CRK28885.1 - 8.4 5.3 28.7 2.1 7.2 24.2 2.1 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 DUF3450 PF11932.8 CRK28885.1 - 9.2 5.5 31.1 5.9 6.1 15.8 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) RRM_1 PF00076.22 CRK28887.1 - 2.4e-18 65.7 0.0 5.7e-18 64.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CRK28887.1 - 0.00039 20.4 0.1 0.00094 19.1 0.1 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 CRK28887.1 - 0.011 15.3 0.0 0.022 14.3 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 CRK28887.1 - 0.064 13.5 5.8 0.14 12.4 0.0 3.3 3 1 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter 4F5 PF04419.14 CRK28889.1 - 3.4e-09 37.4 8.3 3.4e-09 37.4 8.3 2.2 2 0 0 2 2 2 1 4F5 protein family PUF PF00806.19 CRK28890.1 - 5e-06 25.9 0.1 1.2e-05 24.8 0.1 1.6 1 0 0 1 1 1 1 Pumilio-family RNA binding repeat Stc1 PF12898.7 CRK28892.1 - 9.4e-16 58.1 0.5 2.7e-15 56.7 0.1 2.1 2 0 0 2 2 2 1 Stc1 domain BCDHK_Adom3 PF10436.9 CRK28893.1 - 6.9e-34 117.0 0.0 8.2e-34 116.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase 4PPT_N PF17837.1 CRK28893.1 - 0.065 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 4'-phosphopantetheinyl transferase N-terminal domain Tropomyosin_1 PF12718.7 CRK28894.1 - 0.017 15.3 0.8 0.027 14.6 0.8 1.3 1 0 0 1 1 1 0 Tropomyosin like CENP-F_leu_zip PF10473.9 CRK28894.1 - 0.031 14.3 1.8 0.067 13.2 1.8 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NBP1 PF08537.10 CRK28894.1 - 0.11 11.9 1.1 0.21 11.0 1.1 1.4 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 LigT_PEase PF02834.16 CRK28894.1 - 0.13 12.5 0.7 1.5 9.1 0.0 2.6 3 0 0 3 3 3 0 LigT like Phosphoesterase Lectin_N PF03954.14 CRK28894.1 - 0.17 11.6 1.2 0.36 10.6 1.2 1.5 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain Glyco_transf_34 PF05637.12 CRK28895.1 - 2e-61 207.8 0.0 2.7e-61 207.4 0.0 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Pyridoxal_deC PF00282.19 CRK28895.1 - 5.8e-13 48.3 0.0 8.5e-13 47.8 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 CRK28895.1 - 1.9e-05 23.8 0.0 6.8e-05 22.0 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 CRK28895.1 - 0.015 14.6 0.0 0.024 13.9 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 CRK28895.1 - 0.049 12.2 0.0 0.083 11.4 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme RINGv PF12906.7 CRK28896.1 - 1.5e-09 37.8 0.6 1.5e-09 37.8 0.6 2.3 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.6 CRK28896.1 - 0.44 10.9 8.8 0.29 11.5 1.9 2.2 2 0 0 2 2 2 0 Ring finger domain zf-RING_4 PF14570.6 CRK28896.1 - 1.5 8.7 8.6 0.07 12.9 2.6 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 CRK28896.1 - 3.1 8.1 6.1 0.2 11.9 1.0 1.6 2 0 0 2 2 2 0 FANCL C-terminal domain Proteasome PF00227.26 CRK28897.1 - 2.3e-56 190.3 0.0 3.1e-32 111.6 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 CRK28897.1 - 1.2e-10 40.8 0.3 3.1e-10 39.5 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Peptidase_S13 PF02113.15 CRK28897.1 - 0.076 11.7 0.3 7.2 5.2 0.0 2.1 2 0 0 2 2 2 0 D-Ala-D-Ala carboxypeptidase 3 (S13) family Ribonuclease_3 PF00636.26 CRK28899.1 - 6.1e-37 126.5 0.0 3.2e-20 72.7 0.0 2.6 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 CRK28899.1 - 1.2e-22 80.4 0.1 3.3e-10 40.2 0.0 4.1 4 1 0 4 4 4 3 Ribonuclease-III-like Dicer_dimer PF03368.14 CRK28899.1 - 6e-21 74.4 0.0 1.5e-20 73.1 0.0 1.8 1 0 0 1 1 1 1 Dicer dimerisation domain Helicase_C PF00271.31 CRK28899.1 - 2.6e-14 53.5 0.0 7.4e-14 52.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CRK28899.1 - 5.1e-05 23.1 0.0 0.00012 21.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Beta-lactamase PF00144.24 CRK28902.1 - 2.1e-46 158.7 0.0 4.3e-46 157.7 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase PTPLA PF04387.14 CRK28904.1 - 8e-10 38.7 0.4 8.2e-10 38.7 0.4 1.1 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Casein_kappa PF00997.18 CRK28905.1 - 2.5 8.2 10.0 2 8.5 9.2 1.3 1 1 0 1 1 1 0 Kappa casein SLC35F PF06027.12 CRK28906.1 - 4.8e-24 85.4 5.1 5.1e-24 85.3 5.1 1.0 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 CRK28906.1 - 3.4e-06 26.2 0.9 3.9e-06 26.0 0.9 1.0 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 CRK28906.1 - 0.00087 19.5 3.4 0.00093 19.4 3.4 1.1 1 0 0 1 1 1 1 EamA-like transporter family Acetyltransf_1 PF00583.25 CRK28911.1 - 4.5e-07 30.1 0.0 6.2e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 CRK28911.1 - 4.8e-07 29.7 0.0 1.3e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 CRK28911.1 - 7.3e-07 29.5 0.0 1.2e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CRK28911.1 - 2.7e-06 27.3 0.0 5.7e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 CRK28911.1 - 0.0039 17.9 0.0 0.0061 17.2 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 CRK28911.1 - 0.066 12.7 0.0 0.076 12.5 0.0 1.3 1 0 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_CG PF14542.6 CRK28911.1 - 0.08 13.1 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase p450 PF00067.22 CRK28913.1 - 9e-25 87.3 0.0 5e-09 35.4 0.0 4.0 4 0 0 4 4 4 4 Cytochrome P450 HATPase_c PF02518.26 CRK28915.1 - 3.7e-24 85.4 0.1 1.2e-23 83.8 0.1 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 CRK28915.1 - 1.1e-17 64.3 0.0 3.4e-17 62.6 0.0 2.0 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 CRK28915.1 - 9.5e-09 35.2 0.3 2.4e-08 33.9 0.3 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 CRK28915.1 - 0.0065 16.8 0.0 0.016 15.5 0.0 1.7 1 0 0 1 1 1 1 GAF domain KR PF08659.10 CRK28915.1 - 0.018 14.9 0.1 0.045 13.7 0.1 1.6 1 0 0 1 1 1 0 KR domain Tannase PF07519.11 CRK28919.1 - 3.8e-115 385.5 0.2 5.6e-115 384.9 0.2 1.2 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 CRK28919.1 - 0.0019 17.5 0.0 0.098 11.9 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 ATP-synt_A PF00119.20 CRK28920.1 - 0.021 14.8 0.9 0.041 13.8 0.9 1.5 1 1 0 1 1 1 0 ATP synthase A chain XK-related PF09815.9 CRK28921.1 - 0.14 11.2 4.2 0.24 10.4 1.0 2.3 1 1 0 2 2 2 0 XK-related protein ABC_tran PF00005.27 CRK28922.1 - 1.5e-47 161.5 0.0 1.8e-22 80.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 CRK28922.1 - 1.9e-21 75.9 1.7 1.9e-21 75.9 1.7 2.5 4 0 0 4 4 1 1 ABC transporter AAA_21 PF13304.6 CRK28922.1 - 7.4e-18 65.4 0.9 0.00084 19.2 0.0 4.2 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CRK28922.1 - 1.2e-11 44.5 0.2 0.00035 20.1 0.1 4.4 3 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CRK28922.1 - 6.7e-09 35.4 0.1 0.0033 17.1 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 CRK28922.1 - 1e-08 36.0 0.5 0.016 15.7 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.6 CRK28922.1 - 5.6e-07 30.2 0.1 0.04 14.5 0.0 2.8 3 0 0 3 3 2 2 AAA domain RsgA_GTPase PF03193.16 CRK28922.1 - 1.2e-06 28.5 1.0 0.0033 17.4 0.0 2.8 3 0 0 3 3 2 2 RsgA GTPase AAA_15 PF13175.6 CRK28922.1 - 1.5e-06 28.2 0.0 0.028 14.1 0.0 2.7 3 0 0 3 3 2 2 AAA ATPase domain AAA_16 PF13191.6 CRK28922.1 - 1.7e-06 28.5 0.0 0.0088 16.4 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 CRK28922.1 - 2.1e-06 28.2 0.0 0.03 14.7 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 CRK28922.1 - 3.4e-06 27.1 0.0 0.012 15.7 0.1 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_28 PF13521.6 CRK28922.1 - 1.4e-05 25.4 0.0 0.011 16.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CRK28922.1 - 1.6e-05 25.2 0.0 0.075 13.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 CRK28922.1 - 4.7e-05 23.4 0.4 0.2 11.5 0.0 2.8 3 0 0 3 3 2 2 NACHT domain AAA_5 PF07728.14 CRK28922.1 - 9.8e-05 22.4 0.2 0.74 9.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 CRK28922.1 - 0.00017 21.9 0.0 1.1 9.6 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_33 PF13671.6 CRK28922.1 - 0.00042 20.5 0.1 0.67 10.1 0.1 2.9 3 0 0 3 3 2 1 AAA domain NB-ARC PF00931.22 CRK28922.1 - 0.00059 19.1 0.0 1.7 7.8 0.0 3.2 3 0 0 3 3 3 1 NB-ARC domain Roc PF08477.13 CRK28922.1 - 0.00078 19.6 0.1 2 8.6 0.1 3.2 2 1 1 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase AAA_27 PF13514.6 CRK28922.1 - 0.0014 18.3 0.3 0.61 9.6 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.6 CRK28922.1 - 0.0014 18.7 0.0 3.1 7.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.23 CRK28922.1 - 0.0017 18.4 0.3 1.8 8.6 0.0 3.2 4 0 0 4 4 3 1 Dynamin family AAA_24 PF13479.6 CRK28922.1 - 0.0021 17.8 0.4 2 8.1 0.0 3.4 4 0 0 4 4 3 1 AAA domain AAA_25 PF13481.6 CRK28922.1 - 0.0066 16.1 0.1 1 8.9 0.0 3.1 3 1 0 3 3 3 1 AAA domain NTPase_1 PF03266.15 CRK28922.1 - 0.0081 16.1 0.1 0.59 10.0 0.1 2.6 2 0 0 2 2 2 1 NTPase AAA_30 PF13604.6 CRK28922.1 - 0.0082 15.9 0.7 1.1 8.9 0.0 3.2 4 1 0 4 4 3 1 AAA domain AAA_7 PF12775.7 CRK28922.1 - 0.013 15.1 0.0 1 8.8 0.1 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF2813 PF11398.8 CRK28922.1 - 0.018 14.3 0.0 4.6 6.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2813) ATPase_2 PF01637.18 CRK28922.1 - 0.023 14.6 0.0 5.7 6.8 0.0 2.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea MCM PF00493.23 CRK28922.1 - 0.026 13.6 0.0 1.6 7.8 0.0 2.3 2 0 0 2 2 2 0 MCM P-loop domain DUF87 PF01935.17 CRK28922.1 - 0.027 14.6 0.2 6.9 6.7 0.1 3.0 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_17 PF13207.6 CRK28922.1 - 0.035 14.5 0.1 7.7 6.9 0.0 2.8 2 1 0 2 2 2 0 AAA domain DUF815 PF05673.13 CRK28922.1 - 0.037 13.2 0.2 2.3 7.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Ras PF00071.22 CRK28922.1 - 0.047 13.3 0.1 12 5.4 0.0 3.0 3 0 0 3 3 3 0 Ras family TsaE PF02367.17 CRK28922.1 - 0.048 13.7 0.2 14 5.7 0.0 3.1 2 1 1 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_ATPase PF09818.9 CRK28922.1 - 0.1 11.4 0.3 18 4.0 0.0 3.2 3 0 0 3 3 3 0 Predicted ATPase of the ABC class FeoB_N PF02421.18 CRK28922.1 - 0.12 11.9 0.1 10 5.6 0.1 2.7 2 0 0 2 2 2 0 Ferrous iron transport protein B DAP3 PF10236.9 CRK28922.1 - 0.12 11.5 1.5 4.8 6.3 0.1 2.8 2 1 1 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 SbcCD_C PF13558.6 CRK28922.1 - 0.13 12.5 0.8 15 5.9 0.0 3.8 3 2 0 3 3 3 0 Putative exonuclease SbcCD, C subunit DUF3584 PF12128.8 CRK28922.1 - 0.14 9.7 0.4 0.43 8.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) PduV-EutP PF10662.9 CRK28922.1 - 0.17 11.6 0.8 11 5.8 0.0 3.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DBINO PF13892.6 CRK28923.1 - 2.6e-47 160.5 18.6 2.6e-47 160.5 18.6 4.4 3 1 0 3 3 3 1 DNA-binding domain SNF2_N PF00176.23 CRK28923.1 - 2.6e-30 105.4 0.1 4.5e-29 101.3 0.0 2.9 3 0 0 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CRK28923.1 - 9.4e-20 71.0 0.0 3.2e-19 69.3 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CRK28923.1 - 9.8e-06 25.7 0.0 9.8e-06 25.7 0.0 3.2 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 CRK28923.1 - 0.055 12.6 3.2 0.12 11.6 0.0 3.0 2 1 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 Fe_hyd_lg_C PF02906.14 CRK28923.1 - 0.47 10.1 5.4 0.34 10.5 3.4 1.8 2 0 0 2 2 2 0 Iron only hydrogenase large subunit, C-terminal domain Form_Nir_trans PF01226.17 CRK28927.1 - 0.083 12.2 0.7 0.11 11.8 0.7 1.1 1 0 0 1 1 1 0 Formate/nitrite transporter WD40 PF00400.32 CRK28928.1 - 4.6e-06 27.3 0.2 0.037 14.9 0.5 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK28928.1 - 0.00011 22.4 0.0 0.00014 22.1 0.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 CRK28929.1 - 0.027 14.4 0.7 0.052 13.5 0.7 1.5 1 0 0 1 1 1 0 LisH DUF1996 PF09362.10 CRK28930.1 - 6.6e-86 288.1 0.2 8e-86 287.8 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) TFB6 PF17110.5 CRK28930.1 - 2.3e-25 89.3 0.2 3.5e-25 88.7 0.2 1.2 1 0 0 1 1 1 1 Subunit 11 of the general transcription factor TFIIH STE2 PF02116.15 CRK28932.1 - 3.9e-77 259.3 21.8 4.7e-77 259.0 21.8 1.1 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR RNA_pol_Rpb2_6 PF00562.28 CRK28933.1 - 7.5e-119 397.3 0.2 2.5e-75 254.0 0.8 2.5 1 1 1 2 2 2 2 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 CRK28933.1 - 3.6e-55 186.6 0.0 1.1e-54 185.1 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 CRK28933.1 - 1.2e-44 152.2 0.0 2.3e-44 151.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 CRK28933.1 - 1e-33 115.6 0.1 2.5e-33 114.3 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.17 CRK28933.1 - 9.5e-23 80.5 1.4 3e-22 78.9 1.4 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_4 PF04566.13 CRK28933.1 - 6.3e-21 74.4 1.4 2.1e-20 72.7 1.4 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 CRK28933.1 - 1.2e-20 73.4 0.1 3.6e-20 71.9 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 PET117 PF15786.5 CRK28934.1 - 3e-18 65.8 1.9 3.8e-18 65.5 1.9 1.1 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial COX16 PF14138.6 CRK28934.1 - 0.044 14.3 0.3 0.059 13.9 0.3 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 V-ATPase_G PF03179.15 CRK28935.1 - 1e-27 96.7 15.3 1.9e-21 76.6 12.1 2.1 2 0 0 2 2 2 2 Vacuolar (H+)-ATPase G subunit YusW PF14039.6 CRK28935.1 - 0.011 16.2 5.0 0.011 16.2 5.0 1.5 2 0 0 2 2 2 0 YusW-like protein HOIP-UBA PF16678.5 CRK28935.1 - 0.012 15.7 3.9 0.015 15.3 3.9 1.1 1 0 0 1 1 1 0 HOIP UBA domain pair V-ATPase_G_2 PF16999.5 CRK28935.1 - 0.015 15.7 12.6 0.11 12.9 11.1 2.0 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit RNA_polI_A14 PF08203.11 CRK28935.1 - 0.026 15.3 1.2 0.053 14.3 1.2 1.6 1 0 0 1 1 1 0 Yeast RNA polymerase I subunit RPA14 DDHD PF02862.17 CRK28935.1 - 0.43 10.7 3.6 0.49 10.5 3.6 1.2 1 0 0 1 1 1 0 DDHD domain SAPS PF04499.15 CRK28935.1 - 0.45 9.2 7.6 0.5 9.1 7.6 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RRF PF01765.19 CRK28935.1 - 0.86 9.5 12.9 0.48 10.4 10.7 1.6 2 0 0 2 2 2 0 Ribosome recycling factor HAUS6_N PF14661.6 CRK28935.1 - 1.3 8.6 6.4 1.5 8.3 6.4 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF4407 PF14362.6 CRK28935.1 - 3.1 7.1 8.3 3.6 6.8 8.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2203 PF09969.9 CRK28935.1 - 3.8 8.3 7.6 5.3 7.8 7.6 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Sec62 PF03839.16 CRK28935.1 - 9.1 5.7 8.3 12 5.3 8.3 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 MIT PF04212.18 CRK28936.1 - 4.8e-15 55.4 1.1 8.9e-15 54.5 1.1 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Cyclin_N PF00134.23 CRK28937.1 - 8.7e-43 145.1 0.1 1.6e-42 144.2 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CRK28937.1 - 7.7e-35 119.6 0.1 1.9e-34 118.3 0.1 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain TruB_C_2 PF16198.5 CRK28937.1 - 0.0062 16.7 0.1 0.98 9.6 0.1 2.7 2 0 0 2 2 2 2 tRNA pseudouridylate synthase B C-terminal domain Zn_clus PF00172.18 CRK28938.1 - 0.0011 19.0 12.4 0.0021 18.1 12.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHZ PF09649.10 CRK28938.1 - 0.0013 18.1 0.2 0.0062 16.0 0.0 2.1 2 0 0 2 2 2 1 Histone chaperone domain CHZ Abhydrolase_6 PF12697.7 CRK28939.1 - 3.5e-07 31.1 3.5 4.9e-07 30.6 3.5 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 CRK28939.1 - 7.9e-05 22.6 4.0 0.0055 16.6 0.4 3.5 3 1 0 3 3 3 1 alpha/beta hydrolase fold Thioesterase PF00975.20 CRK28939.1 - 0.013 15.6 0.1 0.025 14.7 0.1 1.4 1 0 0 1 1 1 0 Thioesterase domain Hydrolase_4 PF12146.8 CRK28939.1 - 0.032 13.5 0.1 0.34 10.1 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF3089 PF11288.8 CRK28939.1 - 0.059 12.9 0.1 0.27 10.7 0.1 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3089) Abhydrolase_1 PF00561.20 CRK28939.1 - 0.095 12.3 0.0 2.4 7.7 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF915 PF06028.11 CRK28939.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) RNA_pol_Rpc4 PF05132.14 CRK28941.1 - 9.9e-31 107.2 0.0 9.9e-31 107.2 0.0 3.5 3 2 0 3 3 3 1 RNA polymerase III RPC4 UreD PF01774.17 CRK28942.1 - 1.2e-77 260.6 0.3 1.5e-77 260.3 0.3 1.1 1 0 0 1 1 1 1 UreD urease accessory protein STAG PF08514.11 CRK28943.1 - 4.9e-34 116.6 2.2 1.4e-33 115.2 0.3 2.6 2 0 0 2 2 2 1 STAG domain POT1PC PF16686.5 CRK28944.1 - 9.6e-40 136.0 0.1 1.6e-39 135.3 0.1 1.4 1 0 0 1 1 1 1 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 CRK28944.1 - 4.1e-14 52.6 0.0 1.3e-13 51.0 0.0 1.9 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 Arm PF00514.23 CRK28945.1 - 9.2e-94 305.0 15.7 5.1e-13 48.6 0.0 8.4 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 CRK28945.1 - 2.1e-27 95.4 1.7 4.3e-27 94.4 1.7 1.6 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.6 CRK28945.1 - 1.1e-22 80.1 9.2 5.7e-09 36.3 0.1 6.3 5 1 1 6 6 6 4 HEAT-like repeat Arm_3 PF16186.5 CRK28945.1 - 1.1e-22 79.3 5.9 1.5e-22 78.8 4.7 1.9 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_2 PF13646.6 CRK28945.1 - 8.6e-19 67.7 0.2 1.9e-08 34.6 0.0 5.2 1 1 3 5 5 5 3 HEAT repeats HEAT PF02985.22 CRK28945.1 - 2.7e-18 64.5 2.0 1.1e-05 25.2 0.0 7.0 8 0 0 8 8 8 4 HEAT repeat Arm_2 PF04826.13 CRK28945.1 - 2.5e-07 30.4 0.0 0.059 12.8 0.0 4.0 2 1 2 4 4 4 3 Armadillo-like V-ATPase_H_C PF11698.8 CRK28945.1 - 0.00014 22.0 0.0 2.1 8.5 0.0 4.3 3 2 2 5 5 5 2 V-ATPase subunit H Adaptin_N PF01602.20 CRK28945.1 - 0.00019 20.2 0.0 0.012 14.2 0.0 2.6 1 1 0 2 2 2 1 Adaptin N terminal region Cnd1 PF12717.7 CRK28945.1 - 0.0014 18.7 0.0 1 9.4 0.0 2.7 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 CRK28945.1 - 0.0036 17.8 2.7 1.2 10.0 0.3 4.4 4 1 0 4 4 4 1 PBS lyase HEAT-like repeat NopRA1 PF16201.5 CRK28945.1 - 0.061 12.9 0.0 5.1 6.6 0.0 3.5 2 2 3 5 5 5 0 Nucleolar pre-ribosomal-associated protein 1 RICTOR_V PF14668.6 CRK28945.1 - 0.15 12.3 4.7 5.4 7.3 0.1 4.6 3 2 3 6 6 6 0 Rapamycin-insensitive companion of mTOR, domain 5 NUSAP PF16006.5 CRK28945.1 - 2 8.1 4.6 3 7.5 4.6 1.2 1 0 0 1 1 1 0 Nucleolar and spindle-associated protein EF-hand_7 PF13499.6 CRK28946.1 - 3e-17 62.8 3.6 7.9e-09 35.8 0.7 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CRK28946.1 - 3.7e-15 54.5 1.6 4e-07 29.5 0.2 4.5 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 CRK28946.1 - 3.9e-15 54.2 5.8 5.4e-07 28.7 0.4 5.7 7 0 0 7 7 7 2 EF hand EF-hand_5 PF13202.6 CRK28946.1 - 5.3e-12 44.7 4.4 3e-07 29.7 1.1 4.1 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 CRK28946.1 - 2.5e-10 40.0 2.4 0.24 11.3 0.0 5.4 5 1 1 6 6 6 4 EF-hand domain pair EF-hand_9 PF14658.6 CRK28946.1 - 0.027 14.8 0.0 13 6.2 0.0 3.2 3 0 0 3 3 3 0 EF-hand domain LRR_5 PF13306.6 CRK28946.1 - 0.028 14.4 0.0 0.045 13.7 0.0 1.2 1 0 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) Sulfate_transp PF00916.20 CRK28950.1 - 9.6e-47 159.5 5.7 1.5e-46 158.9 5.7 1.1 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 CRK28950.1 - 1.5e-12 47.4 0.0 3.2e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 CRK28950.1 - 2.9e-11 43.0 0.1 5.1e-11 42.2 0.1 1.4 1 0 0 1 1 1 1 STAS domain Sld5 PF05916.11 CRK28951.1 - 1.1e-12 48.3 0.0 1.5e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein Proteasom_Rpn13 PF04683.13 CRK28952.1 - 4.3e-28 97.7 0.0 6.4e-28 97.1 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RPN13_C PF16550.5 CRK28952.1 - 1.4e-08 34.9 0.0 8e-08 32.4 0.0 2.1 1 1 0 1 1 1 1 UCH-binding domain DUF2301 PF10063.9 CRK28953.1 - 0.011 16.1 0.2 0.018 15.4 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized integral membrane protein (DUF2301) IMUP PF15761.5 CRK28953.1 - 0.13 12.9 2.0 0.24 12.1 2.0 1.3 1 0 0 1 1 1 0 Immortalisation up-regulated protein HofP PF10748.9 CRK28953.1 - 0.24 11.0 0.3 1 8.9 0.1 2.0 2 0 0 2 2 2 0 DNA utilization proteins HofP DUF3405 PF11885.8 CRK28954.1 - 1.5e-226 753.0 0.5 2e-226 752.6 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Arf PF00025.21 CRK28955.1 - 2.6e-80 268.0 0.3 3e-80 267.8 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CRK28955.1 - 1.7e-14 54.1 0.0 2.3e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CRK28955.1 - 2e-14 53.4 0.0 2.5e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 CRK28955.1 - 2.6e-13 49.9 1.5 2e-09 37.1 0.5 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 CRK28955.1 - 3.4e-13 49.5 0.0 3.8e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 CRK28955.1 - 1.2e-10 41.1 0.0 1.6e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CRK28955.1 - 2.9e-06 27.3 0.0 4.5e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 CRK28955.1 - 0.0095 15.3 1.0 0.028 13.7 1.0 1.8 1 1 0 1 1 1 1 6-phosphofructo-2-kinase EMP24_GP25L PF01105.24 CRK28956.1 - 1.6e-44 152.1 0.0 1.8e-44 151.9 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD NuiA PF07924.11 CRK28956.1 - 0.056 13.8 0.0 0.097 13.1 0.0 1.4 1 0 0 1 1 1 0 Nuclease A inhibitor-like protein AAA_2 PF07724.14 CRK28957.1 - 8.8e-44 149.6 0.0 6.4e-43 146.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.9 CRK28957.1 - 7.5e-25 86.8 1.9 8.7e-25 86.6 0.1 2.1 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 CRK28957.1 - 1.3e-18 67.7 1.3 4.1e-10 40.2 0.0 2.7 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_9 PF17871.1 CRK28957.1 - 1.6e-15 56.9 12.2 5.2e-14 52.0 5.6 3.5 1 1 1 2 2 2 1 AAA lid domain AAA_5 PF07728.14 CRK28957.1 - 5.3e-13 49.2 0.3 5.7e-09 36.1 0.0 3.4 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CRK28957.1 - 2.7e-09 37.6 3.5 0.0027 18.1 0.1 4.1 2 2 1 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 CRK28957.1 - 3.9e-07 30.4 0.5 0.046 14.0 0.0 3.5 2 2 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 CRK28957.1 - 6e-07 29.3 0.1 0.00059 19.6 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain ATPase_2 PF01637.18 CRK28957.1 - 8.6e-06 25.8 1.7 0.38 10.6 0.5 3.8 2 2 0 2 2 2 1 ATPase domain predominantly from Archaea TniB PF05621.11 CRK28957.1 - 1.8e-05 24.2 0.1 0.0064 15.9 0.1 3.5 3 1 0 3 3 2 1 Bacterial TniB protein NACHT PF05729.12 CRK28957.1 - 4.6e-05 23.4 0.0 0.2 11.5 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_14 PF13173.6 CRK28957.1 - 7.5e-05 22.8 0.0 0.36 10.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 CRK28957.1 - 0.00016 21.2 0.0 0.69 9.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 CRK28957.1 - 0.00033 20.4 0.2 0.44 10.3 0.0 2.7 2 1 0 2 2 2 2 IstB-like ATP binding protein ABC_tran PF00005.27 CRK28957.1 - 0.0012 19.4 0.3 0.31 11.5 0.0 3.2 3 0 0 3 3 3 1 ABC transporter AAA_18 PF13238.6 CRK28957.1 - 0.0018 18.8 0.0 0.32 11.6 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 CRK28957.1 - 0.0028 17.9 0.1 7.4 6.8 0.0 3.6 3 0 0 3 3 3 0 AAA domain Mg_chelatase PF01078.21 CRK28957.1 - 0.006 16.0 0.1 2.7 7.3 0.0 3.0 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI RsgA_GTPase PF03193.16 CRK28957.1 - 0.0061 16.5 0.0 1.8 8.5 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase AAA_24 PF13479.6 CRK28957.1 - 0.0067 16.2 0.0 1.2 8.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CRK28957.1 - 0.0072 16.7 0.0 1.1 9.6 0.0 3.0 2 1 0 2 2 2 1 RNA helicase AAA_30 PF13604.6 CRK28957.1 - 0.0078 16.0 0.3 0.61 9.8 0.0 3.3 3 0 0 3 3 3 1 AAA domain Roc PF08477.13 CRK28957.1 - 0.0094 16.2 0.1 3.5 7.9 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase SRP54 PF00448.22 CRK28957.1 - 0.017 14.7 0.1 0.66 9.6 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ResIII PF04851.15 CRK28957.1 - 0.019 14.9 0.1 14 5.6 0.0 3.4 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit TsaE PF02367.17 CRK28957.1 - 0.02 14.9 0.0 10 6.1 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PduV-EutP PF10662.9 CRK28957.1 - 0.026 14.2 0.2 0.91 9.3 0.0 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation PhoH PF02562.16 CRK28957.1 - 0.028 13.9 0.0 0.6 9.5 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA_25 PF13481.6 CRK28957.1 - 0.031 13.9 0.1 0.56 9.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 CRK28957.1 - 0.035 14.3 0.0 12 6.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 CRK28957.1 - 0.046 12.9 0.8 1.2 8.3 0.3 3.2 3 2 0 3 3 2 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 CRK28957.1 - 0.066 12.5 2.1 2.2 7.5 0.0 3.3 3 1 0 3 3 3 0 Zeta toxin AAA_19 PF13245.6 CRK28957.1 - 0.067 13.5 1.8 0.66 10.3 0.2 3.0 2 2 0 2 2 2 0 AAA domain OEP PF02321.18 CRK28957.1 - 0.19 11.6 2.9 0.81 9.5 3.3 1.8 2 0 0 2 2 1 0 Outer membrane efflux protein PilJ PF13675.6 CRK28957.1 - 0.26 11.3 2.2 1 9.4 0.8 2.7 3 0 0 3 3 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DegS PF05384.11 CRK28957.1 - 0.58 9.6 9.6 1.9 7.9 7.1 2.6 2 1 0 2 2 2 0 Sensor protein DegS Seryl_tRNA_N PF02403.22 CRK28957.1 - 0.61 10.3 11.3 0.43 10.8 8.5 2.2 2 0 0 2 2 1 0 Seryl-tRNA synthetase N-terminal domain DUF4407 PF14362.6 CRK28957.1 - 0.78 9.0 5.7 0.94 8.8 4.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) CENP-F_leu_zip PF10473.9 CRK28957.1 - 0.8 9.7 13.4 3.6 7.6 13.4 2.0 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 UPF0242 PF06785.11 CRK28957.1 - 0.84 9.7 5.8 1.6 8.8 5.8 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus NPV_P10 PF05531.12 CRK28957.1 - 1 9.9 3.3 1.5 9.4 0.9 2.5 2 0 0 2 2 1 0 Nucleopolyhedrovirus P10 protein ADIP PF11559.8 CRK28957.1 - 1.9 8.5 8.8 4.1 7.5 8.8 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding HAUS2 PF15003.6 CRK28957.1 - 2.1 8.0 5.5 1.6 8.4 1.7 2.3 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 2 DUF4061 PF13270.6 CRK28957.1 - 4.3 7.7 5.9 20 5.6 0.2 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4061) APG6_N PF17675.1 CRK28957.1 - 5 7.7 11.6 13 6.3 11.6 1.7 1 0 0 1 1 1 0 Apg6 coiled-coil region UvrD-helicase PF00580.21 CRK28957.1 - 5.5 6.4 7.7 99 2.3 7.6 2.4 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_23 PF13476.6 CRK28957.1 - 6.4 7.2 18.1 2.9e+02 1.8 0.0 3.2 2 1 0 2 2 2 0 AAA domain Ribosomal_L6e PF01159.19 CRK28958.1 - 7.5e-40 135.9 0.3 7.5e-40 135.9 0.3 1.5 2 0 0 2 2 2 1 Ribosomal protein L6e Peptidase_M49 PF03571.15 CRK28959.1 - 1.3e-242 806.1 0.0 2.5e-242 805.2 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M49 2C_adapt PF08793.10 CRK28959.1 - 0.33 11.2 0.9 1.8 8.8 0.8 2.1 2 0 0 2 2 2 0 2-cysteine adaptor domain HATPase_c PF02518.26 CRK28961.1 - 1.5e-20 73.8 0.0 7.4e-20 71.5 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 CRK28961.1 - 8.4e-17 61.4 0.1 1.5e-13 50.9 0.1 3.0 1 1 0 1 1 1 1 Response regulator receiver domain PAS_9 PF13426.7 CRK28961.1 - 9.8e-11 41.8 0.0 0.002 18.3 0.0 3.9 3 0 0 3 3 3 2 PAS domain PAS PF00989.25 CRK28961.1 - 4.4e-09 36.3 0.0 0.0019 18.2 0.0 4.0 3 1 0 3 3 3 2 PAS fold PAS_3 PF08447.12 CRK28961.1 - 1.4e-08 34.9 0.0 8.5e-06 26.0 0.0 3.3 3 0 0 3 3 3 1 PAS fold PAS_4 PF08448.10 CRK28961.1 - 3.9e-08 33.5 1.1 0.35 11.2 0.0 5.4 4 1 0 4 4 4 3 PAS fold HisKA PF00512.25 CRK28961.1 - 6e-08 32.6 0.0 2.7e-07 30.5 0.0 2.2 1 1 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Dabb PF07876.12 CRK28961.1 - 6.5e-07 29.9 0.0 2.6e-06 28.0 0.0 2.0 2 0 0 2 2 2 1 Stress responsive A/B Barrel Domain PAS_8 PF13188.7 CRK28961.1 - 0.0012 18.8 0.0 0.087 12.9 0.0 3.0 2 0 0 2 2 2 1 PAS domain DUF3563 PF12086.8 CRK28961.1 - 0.13 12.0 0.1 0.3 10.8 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3563) Septin PF00735.18 CRK28962.1 - 1.9e-38 132.3 0.1 2.1e-38 132.2 0.1 1.0 1 0 0 1 1 1 1 Septin RRM_1 PF00076.22 CRK28964.1 - 1.1e-16 60.4 0.0 1.8e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 CRK28964.1 - 5.6e-06 26.8 10.2 5.6e-06 26.8 10.2 3.8 4 1 0 4 4 4 1 C-terminal duplication domain of Friend of PRMT1 Nup35_RRM_2 PF14605.6 CRK28964.1 - 0.041 13.9 0.0 0.07 13.1 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif SHR3_chaperone PF08229.11 CRK28965.1 - 2.6e-71 238.5 0.0 4.1e-71 237.8 0.0 1.3 1 0 0 1 1 1 1 ER membrane protein SH3 AAA_11 PF13086.6 CRK28965.1 - 1.7e-58 198.5 0.0 1.3e-57 195.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 CRK28965.1 - 4.2e-47 160.4 0.0 8.8e-47 159.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CRK28965.1 - 4.2e-11 42.9 0.0 4.2e-10 39.7 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CRK28965.1 - 5.2e-08 33.3 0.0 1.4e-07 32.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 CRK28965.1 - 0.00017 21.2 0.0 0.00037 20.1 0.0 1.5 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 CRK28965.1 - 0.00054 20.2 0.6 0.0031 17.8 0.0 2.6 2 1 0 2 2 1 1 AAA domain ResIII PF04851.15 CRK28965.1 - 0.00062 19.8 0.0 0.0039 17.2 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_16 PF13191.6 CRK28965.1 - 0.00065 20.1 0.1 0.011 16.1 0.1 2.7 2 0 0 2 2 2 1 AAA ATPase domain DUF2075 PF09848.9 CRK28965.1 - 0.0014 18.0 0.0 0.015 14.6 0.0 2.2 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 CRK28965.1 - 0.0028 16.8 0.0 0.0055 15.8 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Viral_helicase1 PF01443.18 CRK28965.1 - 0.0034 17.2 0.0 1.6 8.4 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase SlyX PF04102.12 CRK28965.1 - 0.019 15.6 1.1 2.8 8.6 0.2 2.9 2 0 0 2 2 2 0 SlyX PhoH PF02562.16 CRK28965.1 - 0.04 13.4 0.0 0.65 9.4 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein IstB_IS21 PF01695.17 CRK28965.1 - 0.04 13.7 0.0 0.09 12.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 CRK28965.1 - 0.049 13.3 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 CRK28965.1 - 0.051 13.1 0.1 0.63 9.6 0.0 2.9 3 0 0 3 3 3 0 AAA domain Flavi_DEAD PF07652.14 CRK28965.1 - 0.068 13.1 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain TrwB_AAD_bind PF10412.9 CRK28965.1 - 0.091 11.7 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain PCB_OB PF17092.5 CRK28965.1 - 0.32 11.8 2.7 20 6.0 0.1 3.7 3 1 1 4 4 3 0 Penicillin-binding protein OB-like domain Aldo_ket_red PF00248.21 CRK28967.1 - 1.6e-56 191.7 0.0 1.8e-56 191.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Diphthami_syn_2 PF01902.17 CRK28968.1 - 8.4e-24 84.3 0.0 4.4e-19 68.9 0.0 3.3 2 1 0 2 2 2 2 Diphthamide synthase Ribonuc_L-PSP PF01042.21 CRK28968.1 - 9.4e-09 35.3 0.0 1.5e-05 25.0 0.0 3.2 2 1 0 2 2 2 2 Endoribonuclease L-PSP NACHT PF05729.12 CRK28968.1 - 0.00011 22.2 0.0 0.00031 20.7 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 CRK28968.1 - 0.0021 18.3 0.0 0.051 13.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CRK28968.1 - 0.039 14.3 0.0 0.14 12.5 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain KAP_NTPase PF07693.14 CRK28968.1 - 0.17 11.1 0.0 0.67 9.1 0.0 1.8 1 1 0 1 1 1 0 KAP family P-loop domain Fructosamin_kin PF03881.14 CRK28969.1 - 1.7e-31 109.5 0.0 2.3e-31 109.1 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 CRK28969.1 - 0.00024 21.1 0.1 0.00039 20.4 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family SRP54 PF00448.22 CRK28983.1 - 3.8e-26 91.9 0.2 4.2e-26 91.8 0.2 1.0 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain NRDD PF13597.6 CRK28983.1 - 0.22 10.3 0.3 0.25 10.1 0.3 1.0 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase CFEM PF05730.11 CRK28985.1 - 1.7e-26 92.1 47.4 1e-09 38.3 7.8 3.6 3 0 0 3 3 3 3 CFEM domain Apolipoprotein PF01442.18 CRK28985.1 - 0.27 11.1 11.4 7.1 6.5 11.4 2.2 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain adh_short_C2 PF13561.6 CRK28986.1 - 1.8e-61 207.7 1.5 2.1e-61 207.5 1.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRK28986.1 - 1.2e-39 135.8 1.2 1.4e-39 135.6 1.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CRK28986.1 - 4.6e-15 56.0 0.4 6.6e-15 55.5 0.4 1.2 1 0 0 1 1 1 1 KR domain Glyco_hydro_99 PF16317.5 CRK28986.1 - 0.017 14.2 0.0 0.027 13.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 99 Amidase PF01425.21 CRK28987.1 - 6.6e-31 107.8 3.3 1.3e-30 106.8 1.9 1.8 2 0 0 2 2 2 1 Amidase EB1 PF03271.17 CRK28988.1 - 4.3e-18 65.3 5.3 5.8e-16 58.4 1.4 2.6 2 0 0 2 2 2 2 EB1-like C-terminal motif PX PF00787.24 CRK28988.1 - 7.9e-15 54.8 0.0 7.9e-15 54.8 0.0 3.2 3 1 1 4 4 4 1 PX domain CH PF00307.31 CRK28988.1 - 0.067 13.4 1.8 0.97 9.6 0.2 2.4 1 1 1 2 2 2 0 Calponin homology (CH) domain FixQ PF05545.11 CRK28988.1 - 1.3 9.0 4.0 24 5.0 0.3 2.8 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ DEAD PF00270.29 CRK28989.1 - 3.7e-93 310.2 0.5 3e-45 154.1 0.1 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 CRK28989.1 - 7.2e-53 177.6 1.1 2.9e-27 95.2 0.1 3.7 4 0 0 4 4 4 2 Helicase conserved C-terminal domain UTP25 PF06862.12 CRK28989.1 - 2.4e-06 26.6 7.1 0.017 14.0 0.1 4.2 2 2 4 6 6 6 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Phage_integrase PF00589.22 CRK28989.1 - 0.068 13.0 0.0 12 5.7 0.0 2.5 2 0 0 2 2 2 0 Phage integrase family DUF364 PF04016.12 CRK28989.1 - 0.12 12.0 0.2 23 4.6 0.0 2.5 2 0 0 2 2 2 0 Putative heavy-metal chelation AMP-binding PF00501.28 CRK28990.1 - 2.4e-66 224.1 0.1 5.7e-26 91.1 0.1 4.3 3 1 0 3 3 3 3 AMP-binding enzyme DMAP_binding PF06464.11 CRK28990.1 - 1.2e-10 42.2 0.0 3.2e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 DMAP1-binding Domain GvpG PF05120.12 CRK28990.1 - 0.0089 16.0 1.0 0.021 14.8 1.0 1.5 1 0 0 1 1 1 1 Gas vesicle protein G Pkinase_fungal PF17667.1 CRK28992.1 - 9.4e-135 449.5 0.0 1.1e-134 449.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 CRK28992.1 - 0.0063 15.9 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain PDEase_II PF02112.15 CRK28993.1 - 5.4e-45 154.0 0.0 1.1e-20 74.0 0.0 3.3 4 0 0 4 4 4 3 cAMP phosphodiesterases class-II Lactamase_B PF00753.27 CRK28993.1 - 0.019 15.0 0.2 0.043 13.8 0.2 1.7 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily bZIP_C PF12498.8 CRK28993.1 - 0.49 11.4 2.9 1.3 10.0 2.9 1.7 1 0 0 1 1 1 0 Basic leucine-zipper C terminal DUF4045 PF13254.6 CRK28994.1 - 9.1e-90 302.3 43.9 1.8e-53 182.7 32.1 6.1 3 3 2 6 6 6 2 Domain of unknown function (DUF4045) Gelsolin PF00626.22 CRK28994.1 - 1.9e-08 34.1 0.0 0.016 15.1 0.0 3.8 3 0 0 3 3 3 2 Gelsolin repeat Arf PF00025.21 CRK28995.1 - 3.8e-67 225.1 0.6 4.2e-67 225.0 0.6 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 CRK28995.1 - 1.6e-12 47.3 0.0 1.8e-12 47.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CRK28995.1 - 1.8e-12 47.5 0.1 2.5e-12 47.1 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 CRK28995.1 - 2.4e-12 46.7 0.8 6.4e-07 28.8 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CRK28995.1 - 6.3e-10 38.8 0.0 7.5e-10 38.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CRK28995.1 - 2.6e-08 33.9 0.0 4.1e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 CRK28995.1 - 6.5e-08 32.2 0.0 7.5e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 CRK28995.1 - 0.0002 21.0 0.0 0.0042 16.7 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 CRK28995.1 - 0.026 14.0 0.2 0.07 12.7 0.2 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B NACHT PF05729.12 CRK28995.1 - 0.03 14.3 0.2 0.34 10.8 0.0 2.0 2 0 0 2 2 2 0 NACHT domain Dynamin_N PF00350.23 CRK28995.1 - 0.065 13.3 0.0 0.75 9.8 0.0 2.0 2 0 0 2 2 2 0 Dynamin family 6PF2K PF01591.18 CRK28995.1 - 0.13 11.5 0.0 0.3 10.4 0.0 1.6 2 0 0 2 2 2 0 6-phosphofructo-2-kinase RAM PF15320.6 CRK28996.1 - 0.011 16.3 0.1 0.046 14.3 0.1 2.1 1 0 0 1 1 1 0 mRNA cap methylation, RNMT-activating mini protein DUF3336 PF11815.8 CRK28997.1 - 3.5e-54 182.3 2.1 5.3e-54 181.7 2.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 CRK28997.1 - 2.7e-16 60.4 0.2 1.6e-15 57.9 0.2 2.3 1 1 0 1 1 1 1 Patatin-like phospholipase Arf PF00025.21 CRK28998.1 - 4.5e-65 218.3 0.0 5e-65 218.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 CRK28998.1 - 7.7e-11 41.7 0.1 3.3e-07 29.8 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 CRK28998.1 - 9.5e-08 32.3 0.0 3.2e-07 30.6 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CRK28998.1 - 1.6e-07 31.0 0.0 2.2e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 CRK28998.1 - 1.8e-07 30.8 0.0 2.2e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CRK28998.1 - 3.2e-07 30.4 0.0 4.2e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CRK28998.1 - 8.7e-06 25.3 0.0 9.9e-06 25.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CRK28998.1 - 0.0026 17.3 0.1 0.093 12.3 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ATP-synt_DE_N PF02823.16 CRK29000.1 - 3.1e-17 62.2 0.0 4.7e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Flavin_Reduct PF01613.18 CRK29001.1 - 1.1e-17 64.5 0.0 1.6e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain VIT1 PF01988.19 CRK29002.1 - 0.94 9.3 0.0 0.94 9.3 0.0 2.6 2 1 1 3 3 3 0 VIT family IQCJ-SCHIP1 PF15157.6 CRK29002.1 - 1.1 9.1 3.8 2.2 8.1 3.8 1.4 1 0 0 1 1 1 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif LRRFIP PF09738.9 CRK29002.1 - 3.7 6.9 13.1 0.88 9.0 6.4 2.5 2 0 0 2 2 2 0 LRRFIP family Pkinase PF00069.25 CRK29003.1 - 3.1e-24 85.8 0.0 4.6e-24 85.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK29003.1 - 8e-13 48.3 0.0 1.2e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 CRK29003.1 - 0.011 15.4 0.1 0.84 9.2 0.0 2.4 2 1 0 2 2 2 0 RIO1 family TIP41 PF04176.13 CRK29003.1 - 0.053 13.0 0.3 0.099 12.1 0.3 1.4 1 0 0 1 1 1 0 TIP41-like family Kinase-like PF14531.6 CRK29003.1 - 0.087 12.1 0.3 12 5.0 0.0 2.2 2 0 0 2 2 2 0 Kinase-like SR-25 PF10500.9 CRK29003.1 - 1.3 8.6 15.9 0.19 11.3 2.8 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Mtc PF03820.17 CRK29004.1 - 7.3e-115 383.3 0.0 8.6e-115 383.1 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier Lactamase_B_4 PF13691.6 CRK29005.1 - 1.1e-22 79.5 0.0 2.3e-22 78.5 0.0 1.6 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 CRK29005.1 - 4.6e-19 68.7 0.1 1.2e-18 67.4 0.1 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 CRK29005.1 - 0.004 17.2 0.0 0.012 15.6 0.0 1.8 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily DnaJ PF00226.31 CRK29006.1 - 2.2e-09 37.3 0.4 4.6e-09 36.3 0.0 1.8 2 0 0 2 2 2 1 DnaJ domain GCV_T PF01571.21 CRK29007.1 - 1.4e-05 24.6 0.0 2.1e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain BUD22 PF09073.10 CRK29008.1 - 0.028 13.8 19.6 0.035 13.4 19.6 1.2 1 0 0 1 1 1 0 BUD22 DEAD PF00270.29 CRK29009.1 - 6.5e-43 146.5 0.0 1e-41 142.6 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CRK29009.1 - 6.6e-30 103.7 0.1 1.6e-29 102.5 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CRK29009.1 - 3.1e-06 27.3 0.0 8.1e-06 25.9 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 CRK29009.1 - 0.013 14.2 0.0 0.018 13.8 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain AAA_22 PF13401.6 CRK29009.1 - 0.016 15.5 0.1 1.1 9.5 0.0 2.6 2 1 0 2 2 2 0 AAA domain Pkinase PF00069.25 CRK29010.1 - 9e-63 212.1 0.0 1.1e-62 211.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK29010.1 - 6.2e-35 120.7 0.0 8.8e-35 120.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CRK29010.1 - 8e-06 25.4 0.0 1.3e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CRK29010.1 - 0.001 18.0 0.0 0.0014 17.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 CRK29010.1 - 0.0074 15.9 0.0 3 7.4 0.0 2.2 1 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 TruD PF01142.18 CRK29011.1 - 1.1e-27 97.0 0.2 3.8e-23 82.0 0.0 3.1 3 0 0 3 3 3 2 tRNA pseudouridine synthase D (TruD) Sugar_tr PF00083.24 CRK29012.1 - 4.5e-86 289.5 19.6 5.5e-86 289.2 19.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK29012.1 - 1.4e-29 103.1 23.8 2e-29 102.6 23.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Folate_carrier PF01770.18 CRK29012.1 - 0.0038 16.0 0.3 1.3 7.6 0.1 2.2 2 0 0 2 2 2 2 Reduced folate carrier Phage_holin_3_2 PF04550.12 CRK29012.1 - 0.07 13.7 0.8 0.07 13.7 0.8 1.9 2 0 0 2 2 2 0 Phage holin family 2 MFS_1 PF07690.16 CRK29013.1 - 3.4e-27 95.3 33.0 1.3e-26 93.4 32.7 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Amidohydro_2 PF04909.14 CRK29014.1 - 1.1e-28 100.9 3.1 2e-28 100.0 3.1 1.4 1 1 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.21 CRK29014.1 - 0.13 11.6 0.0 0.5 9.7 0.0 1.8 2 0 0 2 2 2 0 TatD related DNase HET PF06985.11 CRK29015.1 - 4.9e-06 26.9 1.0 9.6e-06 26.0 1.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Abhydrolase_6 PF12697.7 CRK29016.1 - 0.00013 22.6 0.5 0.00022 21.9 0.5 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 CRK29016.1 - 0.0013 18.5 0.0 0.0022 17.7 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 CRK29016.1 - 0.0058 16.2 0.0 0.0085 15.6 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 CRK29016.1 - 0.029 13.6 0.4 0.081 12.2 0.0 1.9 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 CRK29016.1 - 0.18 11.6 0.0 0.33 10.7 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Pex14_N PF04695.13 CRK29016.1 - 7.1 7.3 6.8 0.99 10.0 2.5 1.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PTPLA PF04387.14 CRK29017.1 - 2.5e-56 189.9 13.1 3.9e-56 189.3 13.1 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA zf-C2H2 PF00096.26 CRK29018.1 - 7.6e-08 32.4 13.2 0.0015 18.8 2.5 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CRK29018.1 - 8.7e-07 29.3 10.5 0.01 16.6 1.6 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger Zn_clus PF00172.18 CRK29018.1 - 9.4e-06 25.7 9.8 9.4e-06 25.7 9.8 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-H2C2_2 PF13465.6 CRK29018.1 - 0.00022 21.5 4.9 0.00022 21.5 4.9 2.7 3 0 0 3 3 3 1 Zinc-finger double domain Phosphoprotein PF00922.17 CRK29018.1 - 0.052 13.1 0.6 0.11 12.1 0.6 1.4 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein zf-C2H2_6 PF13912.6 CRK29018.1 - 8.3 6.5 9.9 5.5 7.1 1.2 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger Aldedh PF00171.22 CRK29019.1 - 4.2e-14 51.9 0.1 9.5e-12 44.2 0.2 3.0 2 1 0 2 2 2 2 Aldehyde dehydrogenase family Cupin_2 PF07883.11 CRK29021.1 - 3.6e-07 29.8 0.0 5.9e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 CRK29021.1 - 0.003 17.2 0.0 0.014 15.0 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF861) Cupin_1 PF00190.22 CRK29021.1 - 0.065 12.8 0.0 0.094 12.3 0.0 1.2 1 0 0 1 1 1 0 Cupin PepX_C PF08530.10 CRK29022.1 - 4.6e-45 154.3 0.5 7.6e-45 153.6 0.5 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.18 CRK29022.1 - 7.7e-43 147.0 0.3 1.2e-42 146.4 0.3 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) FAA_hydrolase PF01557.18 CRK29022.1 - 1e-17 64.5 0.0 1.8e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 CRK29022.1 - 1.7e-17 63.5 0.0 3e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal Hydrolase_4 PF12146.8 CRK29022.1 - 0.0078 15.5 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 LigB PF02900.18 CRK29023.1 - 1.8e-15 56.7 0.0 2.2e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase FAD_binding_3 PF01494.19 CRK29024.1 - 4e-19 69.1 0.0 6.4e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain ADC PF06314.11 CRK29024.1 - 1e-13 51.4 0.0 2.9e-13 50.0 0.0 1.7 1 1 0 1 1 1 1 Acetoacetate decarboxylase (ADC) Pyr_redox_2 PF07992.14 CRK29024.1 - 3.3e-08 33.1 1.7 2.3e-06 27.1 0.4 2.2 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CRK29024.1 - 1.3e-06 28.3 0.9 2.7e-05 23.9 0.6 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CRK29024.1 - 2.5e-06 27.6 1.1 6.2e-06 26.4 1.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CRK29024.1 - 2.9e-05 23.4 2.3 4.8e-05 22.6 2.3 1.3 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 CRK29024.1 - 0.0001 21.3 0.0 0.015 14.2 0.2 2.5 3 0 0 3 3 3 1 Tryptophan halogenase FAD_oxidored PF12831.7 CRK29024.1 - 0.00047 19.6 0.7 0.0011 18.4 0.7 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 CRK29024.1 - 0.0038 16.5 0.0 0.0066 15.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 CRK29024.1 - 0.0046 17.5 1.9 0.0064 17.0 0.4 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CRK29024.1 - 0.0077 15.0 0.4 0.012 14.3 0.4 1.3 1 0 0 1 1 1 1 HI0933-like protein Amino_oxidase PF01593.24 CRK29024.1 - 0.0091 15.3 0.8 0.34 10.2 0.2 2.3 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase GIDA PF01134.22 CRK29024.1 - 0.012 14.7 0.9 0.019 14.1 0.9 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A ApbA PF02558.16 CRK29024.1 - 0.036 13.7 1.6 0.061 13.0 1.6 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 CRK29024.1 - 0.064 12.5 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 CRK29025.1 - 5.4e-16 58.5 59.5 1.5e-13 50.4 58.5 2.8 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 CRK29025.1 - 3.6e-08 32.3 27.8 5.9e-08 31.6 27.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Orf78 PF06024.12 CRK29025.1 - 0.019 15.3 1.8 0.13 12.5 0.1 2.6 2 0 0 2 2 2 0 Orf78 (ac78) TTc_toxin_rep PF18807.1 CRK29025.1 - 0.15 11.9 0.5 0.36 10.7 0.5 1.5 1 0 0 1 1 1 0 Tripartite Tc toxins repeat Sec62 PF03839.16 CRK29025.1 - 0.33 10.4 2.0 0.83 9.1 2.0 1.7 1 0 0 1 1 1 0 Translocation protein Sec62 GP41 PF00517.17 CRK29025.1 - 4.4 7.2 6.6 1.5 8.7 0.4 2.5 2 0 0 2 2 2 0 Retroviral envelope protein Abhydrolase_3 PF07859.13 CRK29026.1 - 5.7e-29 101.5 0.3 9.1e-14 51.8 0.1 2.4 1 1 1 2 2 2 2 alpha/beta hydrolase fold AATase PF07247.12 CRK29026.1 - 1.7e-07 30.2 0.0 2.2e-05 23.2 0.0 2.1 2 0 0 2 2 2 2 Alcohol acetyltransferase COesterase PF00135.28 CRK29026.1 - 0.0022 16.9 0.0 0.0032 16.4 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Condensation PF00668.20 CRK29026.1 - 0.012 14.3 0.0 0.021 13.5 0.0 1.3 1 0 0 1 1 1 0 Condensation domain DIT1_PvcA PF05141.12 CRK29027.1 - 4.1e-92 308.6 0.0 6e-92 308.0 0.0 1.3 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein AMP-binding PF00501.28 CRK29027.1 - 3.3e-25 88.6 0.0 6.4e-25 87.6 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme MFS_1 PF07690.16 CRK29027.1 - 5.4e-10 38.7 49.9 3e-08 33.0 48.5 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily PP-binding PF00550.25 CRK29027.1 - 1.3e-07 31.9 0.0 3e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Transferase PF02458.15 CRK29027.1 - 2.9e-07 29.5 0.0 1.2e-05 24.2 0.0 2.6 2 1 0 2 2 2 1 Transferase family Cutinase PF01083.22 CRK29028.1 - 7.4e-41 140.0 0.0 9.3e-41 139.7 0.0 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 CRK29028.1 - 0.0098 15.5 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 1 PE-PPE domain Hydrolase_4 PF12146.8 CRK29028.1 - 0.07 12.4 0.0 0.14 11.4 0.0 1.6 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CRK29028.1 - 0.1 13.2 0.0 0.11 13.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family WW PF00397.26 CRK29030.1 - 2.1e-07 30.9 2.9 2.1e-07 30.9 2.9 1.8 2 0 0 2 2 2 1 WW domain WRW PF10206.9 CRK29030.1 - 0.023 15.1 0.2 0.045 14.1 0.2 1.4 1 0 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f DUF4653 PF15546.6 CRK29030.1 - 1.4 8.5 8.6 3 7.4 8.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) MFS_1 PF07690.16 CRK29032.1 - 1.4e-16 60.4 30.8 1.4e-16 60.4 30.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Arylsulfotran_2 PF14269.6 CRK29033.1 - 1.8e-57 195.0 0.5 2.8e-57 194.4 0.5 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 CRK29033.1 - 2.3e-21 76.2 0.1 6.8e-21 74.6 0.1 1.6 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) PQQ PF01011.21 CRK29033.1 - 0.015 15.2 0.1 2.6 8.1 0.0 3.7 4 0 0 4 4 4 0 PQQ enzyme repeat PQQ_2 PF13360.6 CRK29033.1 - 0.036 13.6 0.4 0.15 11.6 0.2 2.3 2 1 0 2 2 2 0 PQQ-like domain Sod_Cu PF00080.20 CRK29034.1 - 8.4e-11 42.2 0.1 2.3e-10 40.8 0.0 1.7 2 0 0 2 2 2 1 Copper/zinc superoxide dismutase (SODC) Sod_Cu PF00080.20 CRK29035.1 - 1e-11 45.1 0.0 1.6e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Rhodanese PF00581.20 CRK29037.1 - 1.3e-05 25.6 0.0 1.8e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain C1ORF64 PF15547.6 CRK29037.1 - 0.044 14.2 0.0 0.078 13.4 0.0 1.3 1 0 0 1 1 1 0 Steroid receptor-associated and regulated protein AlkA_N PF06029.11 CRK29038.1 - 0.12 12.7 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 AlkA N-terminal domain zf-H2C2_2 PF13465.6 CRK29039.1 - 2e-11 43.8 18.5 1.1e-06 28.7 3.1 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 CRK29039.1 - 4.8e-08 33.0 24.2 0.0046 17.3 7.4 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type ATG16 PF08614.11 CRK29039.1 - 6.6e-08 33.0 2.0 6.6e-08 33.0 2.0 2.1 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) zf-C2H2_4 PF13894.6 CRK29039.1 - 1.4e-07 31.8 21.2 0.042 14.7 6.1 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CRK29039.1 - 0.0003 20.7 18.8 0.047 13.7 0.1 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger FAM76 PF16046.5 CRK29039.1 - 0.0018 17.7 0.1 0.0018 17.7 0.1 2.6 2 1 0 2 2 2 1 FAM76 protein Rad50_zn_hook PF04423.14 CRK29039.1 - 0.0035 17.2 2.3 0.089 12.7 0.5 2.5 2 0 0 2 2 2 1 Rad50 zinc hook motif APG6_N PF17675.1 CRK29039.1 - 0.0068 16.9 1.0 0.0068 16.9 1.0 1.8 2 0 0 2 2 1 1 Apg6 coiled-coil region Macoilin PF09726.9 CRK29039.1 - 0.011 14.3 0.5 0.017 13.7 0.5 1.2 1 0 0 1 1 1 0 Macoilin family Filament PF00038.21 CRK29039.1 - 0.023 14.3 5.0 0.036 13.7 5.0 1.2 1 0 0 1 1 1 0 Intermediate filament protein zf-C2H2_9 PF16293.5 CRK29039.1 - 0.023 14.5 4.0 1.6 8.6 0.4 3.2 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) FlxA PF14282.6 CRK29039.1 - 0.031 14.3 8.9 0.16 12.0 8.9 2.2 1 0 0 1 1 1 0 FlxA-like protein zf-C2HC_2 PF13913.6 CRK29039.1 - 0.038 13.9 1.1 0.038 13.9 1.1 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Zn-ribbon_8 PF09723.10 CRK29039.1 - 0.044 13.9 6.4 0.053 13.7 1.8 2.5 2 0 0 2 2 2 0 Zinc ribbon domain zf-Di19 PF05605.12 CRK29039.1 - 0.069 13.4 11.1 0.14 12.4 6.1 2.5 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding ZnuA PF01297.17 CRK29039.1 - 0.099 12.0 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic Fez1 PF06818.15 CRK29039.1 - 0.1 13.1 4.4 0.23 11.9 4.4 1.6 1 0 0 1 1 1 0 Fez1 DZR PF12773.7 CRK29039.1 - 0.24 11.5 6.4 1.2 9.2 6.2 2.1 1 1 1 2 2 2 0 Double zinc ribbon zf-C2H2_jaz PF12171.8 CRK29039.1 - 0.3 11.4 10.7 2.9 8.3 3.3 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zinc_ribbon_9 PF14369.6 CRK29039.1 - 0.3 11.4 5.6 36 4.7 0.1 3.4 3 0 0 3 3 3 0 zinc-ribbon DUF4407 PF14362.6 CRK29039.1 - 0.3 10.4 4.7 0.55 9.5 4.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 CRK29039.1 - 0.36 9.7 4.4 0.58 9.0 4.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein zf-BED PF02892.15 CRK29039.1 - 0.89 9.6 8.4 1 9.5 3.6 2.6 1 1 1 2 2 2 0 BED zinc finger HypA PF01155.19 CRK29039.1 - 1.1 9.4 3.3 4 7.5 3.3 1.9 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-CHCC PF10276.9 CRK29039.1 - 1.3 9.2 5.4 3.2 7.9 0.6 3.1 3 0 0 3 3 3 0 Zinc-finger domain CC2-LZ PF16516.5 CRK29039.1 - 2.3 8.7 7.5 2 8.8 3.0 2.2 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator zinc-ribbons_6 PF07191.12 CRK29039.1 - 3.4 7.7 5.7 17 5.5 5.7 2.0 1 1 0 1 1 1 0 zinc-ribbons zinc_ribbon_5 PF13719.6 CRK29039.1 - 3.5 7.4 5.8 17 5.3 0.1 3.0 3 0 0 3 3 3 0 zinc-ribbon domain LPP PF04728.13 CRK29039.1 - 4.1 7.9 8.5 97 3.5 8.5 2.6 1 1 0 1 1 1 0 Lipoprotein leucine-zipper zf-UDP PF14569.6 CRK29039.1 - 5.4 7.2 9.1 19 5.4 0.5 3.0 1 1 0 2 2 2 0 Zinc-binding RING-finger bZIP_1 PF00170.21 CRK29040.1 - 0.00039 20.5 18.4 0.059 13.5 0.7 5.2 4 0 0 4 4 4 2 bZIP transcription factor TMF_DNA_bd PF12329.8 CRK29040.1 - 0.0013 18.7 1.7 0.0013 18.7 1.7 5.8 4 1 1 5 5 5 1 TATA element modulatory factor 1 DNA binding EzrA PF06160.12 CRK29040.1 - 0.022 13.0 6.4 0.039 12.1 6.4 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA NPV_P10 PF05531.12 CRK29040.1 - 0.67 10.5 3.7 8.3 7.0 3.7 2.9 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.11 CRK29040.1 - 1.3 7.8 14.9 0.0046 15.9 5.1 1.8 2 0 0 2 2 2 0 Spc7 kinetochore protein AAA_13 PF13166.6 CRK29040.1 - 1.7 7.2 6.9 4.5 5.8 6.9 1.7 1 0 0 1 1 1 0 AAA domain Hfx_Cass5 PF18287.1 CRK29041.1 - 0.38 11.0 0.1 0.38 11.0 0.1 1.8 2 0 0 2 2 2 0 Integron Cassette Protein Hfx_Cass5 URO-D PF01208.17 CRK29042.1 - 6.2e-62 209.8 0.0 9.3e-62 209.2 0.0 1.3 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) DUF3138 PF11336.8 CRK29042.1 - 0.04 12.5 0.1 0.08 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Csm1_N PF18504.1 CRK29042.1 - 0.042 14.2 0.7 0.13 12.6 0.7 1.9 1 0 0 1 1 1 0 Csm1 N-terminal domain Cut12 PF11500.8 CRK29042.1 - 0.056 13.4 0.1 0.1 12.5 0.1 1.5 1 0 0 1 1 1 0 Spindle pole body formation-associated protein ADIP PF11559.8 CRK29042.1 - 0.11 12.6 1.0 0.25 11.4 1.0 1.6 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding RolB_RolC PF02027.17 CRK29042.1 - 0.18 11.4 0.2 0.39 10.4 0.2 1.5 1 0 0 1 1 1 0 RolB/RolC glucosidase family DUF641 PF04859.12 CRK29042.1 - 0.19 12.0 1.8 0.33 11.3 0.2 2.1 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) PKcGMP_CC PF16808.5 CRK29042.1 - 1.5 8.7 5.2 1.3 8.9 1.0 2.4 1 1 1 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase IMUP PF15761.5 CRK29043.1 - 7e-05 23.5 4.9 0.00016 22.4 1.7 2.3 2 0 0 2 2 2 1 Immortalisation up-regulated protein Chorion_2 PF03964.15 CRK29043.1 - 0.00034 21.4 3.5 0.16 12.8 0.6 3.7 3 2 0 3 3 3 2 Chorion family 2 Hfx_Cass5 PF18287.1 CRK29043.1 - 0.091 13.0 1.1 0.3 11.3 0.0 2.1 2 0 0 2 2 2 0 Integron Cassette Protein Hfx_Cass5 AZUL PF16558.5 CRK29043.1 - 0.72 10.1 3.5 0.49 10.7 0.2 2.3 2 0 0 2 2 2 0 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A URO-D PF01208.17 CRK29045.1 - 6.6e-123 410.3 0.0 7.4e-123 410.1 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) DUF3602 PF12223.8 CRK29046.1 - 9e-15 55.0 11.2 1.2e-12 48.2 1.3 2.6 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) DUF3602 PF12223.8 CRK29047.1 - 2.9e-14 53.4 12.6 1.2e-12 48.2 1.5 2.5 2 1 1 3 3 3 2 Protein of unknown function (DUF3602) Velvet PF11754.8 CRK29048.1 - 1.7e-89 300.1 10.8 3.3e-89 299.1 0.0 2.2 2 0 0 2 2 2 1 Velvet factor RhoGEF PF00621.20 CRK29050.1 - 3.5e-57 193.6 0.0 4e-27 95.6 0.0 2.7 2 0 0 2 2 2 2 RhoGEF domain LPD13 PF18825.1 CRK29050.1 - 1.6e-08 34.4 0.2 0.0052 16.5 0.0 2.5 2 0 0 2 2 2 2 Large polyvalent protein-associated domain 13 Curto_V2 PF07325.11 CRK29050.1 - 0.00012 21.9 0.7 0.64 9.9 0.1 2.4 2 0 0 2 2 2 2 Curtovirus V2 protein Desulfoferrodox PF01880.18 CRK29050.1 - 0.0043 17.6 1.1 12 6.6 0.0 4.1 4 0 0 4 4 4 1 Desulfoferrodoxin TGF_beta_GS PF08515.12 CRK29050.1 - 0.011 15.1 1.6 5.7 6.5 0.1 3.1 2 0 0 2 2 2 0 Transforming growth factor beta type I GS-motif VirB7 PF17413.2 CRK29050.1 - 0.021 14.2 0.0 9.4 5.6 0.0 2.6 2 0 0 2 2 2 0 Outer membrane lipoprotein virB7 Arc PF03869.14 CRK29050.1 - 0.075 12.9 0.1 18 5.3 0.0 2.6 2 0 0 2 2 2 0 Arc-like DNA binding domain FAM176 PF14851.6 CRK29051.1 - 5.1 6.8 5.0 1.3 8.7 1.7 1.6 2 0 0 2 2 2 0 FAM176 family Telomerase_RBD PF12009.8 CRK29052.1 - 1.1e-42 145.3 0.3 3.1e-42 143.8 0.1 1.8 2 0 0 2 2 2 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 CRK29052.1 - 6e-16 58.6 0.0 1.7e-09 37.6 0.0 2.6 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) CN_hydrolase PF00795.22 CRK29053.1 - 6.1e-30 104.4 0.0 3e-15 56.3 0.1 2.3 1 1 1 2 2 2 2 Carbon-nitrogen hydrolase Glyco_transf_28 PF03033.20 CRK29053.1 - 2.2e-23 82.9 0.0 6.2e-23 81.4 0.0 1.9 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 CRK29053.1 - 8.8e-07 28.1 0.0 1.5e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CRK29053.1 - 0.01 15.8 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain VPS13_C PF16909.5 CRK29053.1 - 0.011 15.5 0.2 0.03 14.1 0.2 1.7 1 0 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal Zn_clus PF00172.18 CRK29054.1 - 1.7e-09 37.6 8.3 3.2e-09 36.8 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 CRK29054.1 - 1e-06 27.8 0.6 1.6e-06 27.2 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain HATPase_c PF02518.26 CRK29056.1 - 8.1e-28 97.2 0.1 7e-26 90.9 0.1 3.0 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 CRK29056.1 - 4e-27 94.6 0.7 7.1e-27 93.8 0.7 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 CRK29056.1 - 4.6e-14 52.2 0.0 1e-13 51.1 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 CRK29056.1 - 0.002 18.5 0.0 0.022 15.1 0.0 2.4 2 0 0 2 2 2 1 HAMP domain HET PF06985.11 CRK29059.1 - 0.0016 18.8 0.0 0.0025 18.2 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF2533 PF10752.9 CRK29059.1 - 0.034 14.6 0.0 14 6.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2533) Archaeal_AmoA PF12942.7 CRK29059.1 - 0.19 11.4 0.1 24 4.6 0.0 2.2 2 0 0 2 2 2 0 Archaeal ammonia monooxygenase subunit A (AmoA) zf-CCHC PF00098.23 CRK29061.1 - 4.3 7.6 38.4 0.12 12.4 6.8 4.7 5 0 0 5 5 5 0 Zinc knuckle zf-CCHC PF00098.23 CRK29062.1 - 4.2 7.6 38.4 0.12 12.5 6.8 4.7 5 0 0 5 5 5 0 Zinc knuckle ORMDL PF04061.14 CRK29063.1 - 1e-108 358.9 13.6 3.1e-54 182.5 3.1 2.2 2 0 0 2 2 2 2 ORMDL family Methyltransf_3 PF01596.17 CRK29063.1 - 3.9e-51 173.3 0.0 2.5e-28 98.7 0.0 2.3 2 0 0 2 2 2 2 O-methyltransferase PCMT PF01135.19 CRK29063.1 - 5.2e-20 72.1 0.1 5.6e-09 36.1 0.0 2.2 2 0 0 2 2 2 2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.6 CRK29063.1 - 7.7e-18 65.5 0.0 8.2e-08 33.2 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 CRK29063.1 - 3.1e-14 53.0 0.0 6.4e-06 26.0 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 CRK29063.1 - 5.4e-13 49.5 0.0 4.4e-05 24.1 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain GCD14 PF08704.10 CRK29063.1 - 7.6e-06 25.8 0.0 0.12 12.0 0.0 2.3 2 0 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_4 PF02390.17 CRK29063.1 - 4.9e-05 22.9 0.0 0.31 10.5 0.0 2.4 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_11 PF08241.12 CRK29063.1 - 0.0024 18.5 0.1 4.4 8.0 0.0 2.9 2 1 0 2 2 2 2 Methyltransferase domain HATPase_c_3 PF13589.6 CRK29067.1 - 0.16 11.8 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Glypican PF01153.19 CRK29068.1 - 6.2 5.5 11.0 10 4.8 11.0 1.3 1 0 0 1 1 1 0 Glypican Hexapep PF00132.24 CRK29071.1 - 4.3e-11 42.1 25.6 1e-06 28.2 7.8 4.5 4 1 0 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 CRK29071.1 - 8.5e-08 31.8 27.4 0.0005 19.8 8.8 3.6 4 0 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.8 CRK29071.1 - 0.00018 21.7 0.1 0.00027 21.1 0.1 1.2 1 0 0 1 1 1 1 Maltose acetyltransferase Proteasome PF00227.26 CRK29083.1 - 2.9e-36 124.7 0.0 3.5e-36 124.5 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit DUF3383 PF11863.8 CRK29083.1 - 0.035 13.1 0.0 0.042 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3383) GluRS_N PF18466.1 CRK29083.1 - 0.58 10.6 3.5 0.26 11.7 1.2 1.6 2 0 0 2 2 2 0 Glutamate--tRNA ligase N-terminal domain WD40 PF00400.32 CRK29085.1 - 2.8e-23 81.8 2.7 4.5e-06 27.3 0.0 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK29085.1 - 0.00078 19.7 0.0 0.14 12.5 0.0 3.0 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CRK29085.1 - 0.0026 16.5 0.0 0.36 9.4 0.1 2.8 2 1 1 3 3 3 2 Nucleoporin Nup120/160 WD40_like PF17005.5 CRK29085.1 - 0.012 15.0 0.0 0.045 13.1 0.0 1.9 2 1 0 2 2 2 0 WD40-like domain Peptidase_C48 PF02902.19 CRK29086.1 - 4.9e-27 95.2 0.0 1.1e-26 94.1 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DNApol3-delta_C PF09115.10 CRK29086.1 - 0.059 13.9 0.1 0.12 12.8 0.1 1.5 1 0 0 1 1 1 0 DNA polymerase III, delta subunit, C terminal Pmp3 PF01679.17 CRK29089.1 - 1.2e-13 51.0 9.6 2.2e-13 50.1 9.6 1.4 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF872 PF05915.12 CRK29089.1 - 0.024 14.8 0.1 0.054 13.7 0.1 1.5 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) zf-RanBP PF00641.18 CRK29091.1 - 2.6e-18 65.0 13.3 8.8e-11 40.9 1.6 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.22 CRK29091.1 - 5.4e-08 32.6 0.0 1.1e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.24 CRK29091.1 - 2.7e-05 24.8 0.0 4.1e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Exonuclease CAF1C_H4-bd PF12265.8 CRK29094.1 - 4e-27 94.3 0.3 2.9e-26 91.5 0.1 2.6 3 0 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 CRK29094.1 - 2e-26 91.7 5.6 2.5e-06 28.1 0.2 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK29094.1 - 6.1e-07 29.7 0.3 0.18 12.1 0.1 4.1 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain XRN_N PF03159.18 CRK29095.1 - 1.7e-98 328.9 0.1 6.3e-98 327.0 0.0 1.8 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 CRK29095.1 - 1.2e-57 195.8 3.2 1.8e-57 195.3 3.2 1.2 1 0 0 1 1 1 1 Xrn1 helical domain DsrD PF08679.11 CRK29095.1 - 0.086 13.1 0.7 0.22 11.8 0.1 2.0 2 0 0 2 2 2 0 Dissimilatory sulfite reductase D (DsrD) DUF2533 PF10752.9 CRK29095.1 - 0.1 13.0 0.1 0.29 11.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2533) Thioredoxin_11 PF18078.1 CRK29095.1 - 4.3 7.5 6.9 0.58 10.3 1.7 2.1 2 0 0 2 2 2 0 Thioredoxin-like SNTX domain XRN1_D1 PF18332.1 CRK29096.1 - 7e-74 247.8 0.1 1e-73 247.2 0.1 1.3 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain XRN1_D2_D3 PF18334.1 CRK29096.1 - 1.6e-33 114.7 0.1 7e-33 112.7 0.0 2.1 2 0 0 2 2 2 1 Exoribonuclease Xrn1 D2/D3 domain SH3_12 PF18129.1 CRK29096.1 - 1.5e-21 76.3 0.2 2.9e-21 75.3 0.2 1.5 1 0 0 1 1 1 1 Xrn1 SH3-like domain XRN_M PF17846.1 CRK29096.1 - 1.4e-12 47.3 0.0 2.4e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Xrn1 helical domain Xrn1_D3 PF18194.1 CRK29096.1 - 3.1e-05 24.0 0.1 7.6e-05 22.7 0.1 1.7 1 0 0 1 1 1 1 Exoribonuclease 1 Domain-3 SPC22 PF04573.12 CRK29097.1 - 5.5e-12 45.5 3.4 1.2e-09 37.8 0.1 2.0 1 1 1 2 2 2 2 Signal peptidase subunit Pkinase PF00069.25 CRK29098.1 - 1.8e-68 230.8 0.0 2.4e-68 230.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK29098.1 - 3e-35 121.8 0.0 5.6e-35 120.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CRK29098.1 - 0.019 13.9 0.1 0.047 12.6 0.0 1.5 2 0 0 2 2 2 0 Haspin like kinase domain Kinase-like PF14531.6 CRK29098.1 - 0.044 13.1 0.0 0.07 12.4 0.0 1.2 1 0 0 1 1 1 0 Kinase-like MFS_1 PF07690.16 CRK29102.1 - 2.9e-38 131.7 23.5 2.9e-38 131.7 23.5 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily SET PF00856.28 CRK29103.1 - 3.7e-10 40.5 0.0 1.5e-09 38.5 0.0 1.9 1 1 0 1 1 1 1 SET domain SAF PF08666.12 CRK29103.1 - 0.15 12.7 0.2 15 6.3 0.1 2.5 2 0 0 2 2 2 0 SAF domain Pyridoxal_deC PF00282.19 CRK29107.1 - 5.4e-75 252.4 0.0 6e-75 252.3 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 CRK29107.1 - 0.00016 20.8 0.0 0.00025 20.1 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 CRK29107.1 - 0.00035 19.9 0.0 0.00042 19.7 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Ras PF00071.22 CRK29108.1 - 3.6e-39 133.9 0.0 2.7e-25 88.9 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 CRK29108.1 - 1.5e-11 44.5 0.1 3.2e-11 43.5 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 CRK29108.1 - 0.0029 17.7 0.0 0.0046 17.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 CRK29108.1 - 0.008 15.7 0.0 0.022 14.2 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family PRK PF00485.18 CRK29108.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GTP_EFTU PF00009.27 CRK29108.1 - 0.12 11.9 0.1 1.3 8.5 0.0 2.3 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain XFP_N PF09364.10 CRK29109.1 - 2.6e-165 549.6 0.0 3.5e-165 549.2 0.0 1.2 1 0 0 1 1 1 1 XFP N-terminal domain XFP PF03894.15 CRK29109.1 - 4.9e-80 267.4 0.0 7.8e-80 266.7 0.0 1.3 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase XFP_C PF09363.10 CRK29109.1 - 8.1e-80 267.0 0.0 1.2e-79 266.5 0.0 1.3 1 0 0 1 1 1 1 XFP C-terminal domain Formyl_trans_N PF00551.19 CRK29112.1 - 8.7e-29 100.5 0.1 2.1e-28 99.3 0.1 1.6 1 1 0 1 1 1 1 Formyl transferase Glyco_hydro_17 PF00332.18 CRK29113.1 - 8.7e-09 35.4 0.2 4.5e-08 33.1 0.0 1.9 1 1 0 2 2 2 1 Glycosyl hydrolases family 17 Aminotran_1_2 PF00155.21 CRK29114.1 - 4.1e-21 75.6 0.0 5.2e-21 75.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Glucan_synthase PF02364.15 CRK29115.1 - 0 1362.7 0.0 0 1362.0 0.0 1.4 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 CRK29115.1 - 2.5e-43 147.5 0.8 8.2e-43 145.8 0.8 2.0 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 SprT-like PF10263.9 CRK29116.1 - 1.9e-36 124.4 0.3 3.2e-36 123.6 0.3 1.4 1 0 0 1 1 1 1 SprT-like family Zn_ribbon_SprT PF17283.2 CRK29116.1 - 2.5e-10 40.1 4.3 4.4e-10 39.3 4.3 1.4 1 0 0 1 1 1 1 SprT-like zinc ribbon domain CHDNT PF08073.12 CRK29116.1 - 0.00019 21.4 0.2 0.0004 20.3 0.2 1.5 1 0 0 1 1 1 1 CHDNT (NUC034) domain HMG_box PF00505.19 CRK29116.1 - 0.014 15.8 0.1 0.032 14.6 0.1 1.6 1 0 0 1 1 1 0 HMG (high mobility group) box YABBY PF04690.13 CRK29116.1 - 0.041 14.4 0.1 0.057 14.0 0.1 1.3 1 0 0 1 1 1 0 YABBY protein Peptidase_M90 PF06167.12 CRK29116.1 - 0.045 13.3 0.3 0.11 12.1 0.1 1.7 2 0 0 2 2 2 0 Glucose-regulated metallo-peptidase M90 Zn-ribbon_8 PF09723.10 CRK29116.1 - 0.051 13.7 0.7 0.1 12.7 0.7 1.5 1 0 0 1 1 1 0 Zinc ribbon domain Ccdc124 PF06244.12 CRK29116.1 - 0.11 13.1 0.3 0.22 12.1 0.3 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 124 /Oxs1 DUF4379 PF14311.6 CRK29116.1 - 0.37 11.2 2.1 1.3 9.4 2.1 2.0 1 1 0 1 1 1 0 Probable Zinc-ribbon domain Mog1 PF04603.12 CRK29117.1 - 1.2e-38 132.6 0.0 1.4e-38 132.4 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein HIT PF01230.23 CRK29118.1 - 9.4e-17 61.6 0.0 1.4e-16 61.0 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 CRK29118.1 - 1.2e-08 35.4 0.1 1.8e-08 34.9 0.1 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 CRK29118.1 - 0.0019 18.0 0.4 0.003 17.4 0.4 1.5 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CRAL_TRIO PF00650.20 CRK29119.1 - 1.6e-42 144.9 0.1 2.7e-42 144.2 0.1 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CRK29119.1 - 1.3e-15 57.3 0.6 4.2e-15 55.7 0.1 2.2 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 CRK29119.1 - 2.3e-08 34.3 0.0 5e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DASH_Dam1 PF08653.10 CRK29120.1 - 4.5e-28 96.8 2.2 7.3e-28 96.1 2.2 1.4 1 0 0 1 1 1 1 DASH complex subunit Dam1 zf-C2H2_jaz PF12171.8 CRK29121.1 - 2.3e-10 40.5 0.5 4e-10 39.7 0.5 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-SCNM1 PF15803.5 CRK29121.1 - 0.017 14.8 0.0 0.034 13.8 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of sodium channel modifier 1 zf-C2H2_2 PF12756.7 CRK29121.1 - 0.033 14.5 0.5 0.074 13.4 0.5 1.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 CRK29121.1 - 0.086 13.7 0.7 0.17 12.8 0.2 1.8 2 0 0 2 2 2 0 C2H2-type zinc finger Gaa1 PF04114.14 CRK29123.1 - 1.7e-51 175.8 12.8 2.1e-51 175.5 12.8 1.0 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component PCI PF01399.27 CRK29124.1 - 4.9e-11 43.1 0.0 1e-10 42.1 0.0 1.6 1 0 0 1 1 1 1 PCI domain Rpn9_C PF18261.1 CRK29124.1 - 1.6e-08 34.0 0.3 3.7e-08 32.8 0.3 1.6 1 0 0 1 1 1 1 Rpn9 C-terminal helix TPR_MalT PF17874.1 CRK29124.1 - 0.065 12.6 0.1 0.095 12.1 0.1 1.2 1 0 0 1 1 1 0 MalT-like TPR region Pec_lyase_C PF00544.19 CRK29125.1 - 0.0022 17.6 0.1 0.0025 17.4 0.1 1.1 1 0 0 1 1 1 1 Pectate lyase Gly_transf_sug PF04488.15 CRK29126.1 - 3.1e-06 27.7 0.0 5.8e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 CRK29126.1 - 0.28 10.4 0.0 0.88 8.8 0.0 1.7 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain OPA3 PF07047.12 CRK29127.1 - 2.3e-34 117.8 12.0 4.8e-34 116.8 10.7 2.2 1 1 0 1 1 1 1 Optic atrophy 3 protein (OPA3) Bac_luciferase PF00296.20 CRK29127.1 - 0.032 13.6 2.1 0.058 12.8 2.1 1.4 1 0 0 1 1 1 0 Luciferase-like monooxygenase Presenilin PF01080.17 CRK29127.1 - 0.4 9.4 2.2 0.37 9.5 2.2 1.1 1 0 0 1 1 1 0 Presenilin Connexin PF00029.19 CRK29127.1 - 0.91 9.2 2.4 1.4 8.6 2.4 1.3 1 0 0 1 1 1 0 Connexin GST_C PF00043.25 CRK29127.1 - 0.91 9.8 4.4 5.8 7.2 0.1 2.3 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain RNA_pol_Rpc4 PF05132.14 CRK29127.1 - 1.5 9.3 7.7 0.17 12.3 3.6 1.5 2 0 0 2 2 2 0 RNA polymerase III RPC4 RR_TM4-6 PF06459.12 CRK29127.1 - 3.2 7.5 10.8 1.5 8.6 6.2 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DDHD PF02862.17 CRK29127.1 - 3.5 7.7 7.0 3.2 7.9 6.3 1.3 1 1 0 1 1 1 0 DDHD domain HAUS6_N PF14661.6 CRK29127.1 - 3.7 7.1 12.8 1.2 8.6 6.9 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Peptidase_S49_N PF08496.10 CRK29127.1 - 4.8 7.2 8.7 4 7.5 4.1 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Tho2 PF11262.8 CRK29127.1 - 5 6.2 9.8 19 4.4 0.1 2.3 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 V_ATPase_I PF01496.19 CRK29127.1 - 5.2 4.9 7.3 17 3.2 0.0 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF4337 PF14235.6 CRK29127.1 - 5.6 7.1 15.6 2 8.5 6.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) FemAB PF02388.16 CRK29127.1 - 7.1 5.4 10.5 1.2 8.0 4.6 1.9 2 0 0 2 2 2 0 FemAB family DUF4140 PF13600.6 CRK29127.1 - 8.1 7.0 12.4 3.7 8.1 0.7 2.4 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) SBDS PF01172.18 CRK29130.1 - 1.6e-24 85.7 0.2 1.9e-24 85.5 0.2 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein RhoGEF PF00621.20 CRK29131.1 - 8.4e-19 68.5 0.0 2.1e-18 67.2 0.0 1.7 1 1 0 1 1 1 1 RhoGEF domain E1-E2_ATPase PF00122.20 CRK29132.1 - 1.2e-48 165.1 5.1 3e-48 163.7 2.4 2.7 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 CRK29132.1 - 2.2e-45 154.6 5.9 2.2e-45 154.6 5.9 1.7 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 CRK29132.1 - 6.2e-24 85.5 2.2 1.2e-22 81.3 2.2 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CRK29132.1 - 7.7e-22 77.2 0.0 1.5e-21 76.2 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 CRK29132.1 - 1.3e-19 69.6 0.0 3.5e-19 68.2 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CRK29132.1 - 6.1e-09 36.0 1.9 1.1e-06 28.6 1.3 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 CRK29132.1 - 9.9e-06 26.1 0.0 3.8e-05 24.2 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Proteasome PF00227.26 CRK29133.1 - 3.6e-40 137.5 0.0 4.3e-40 137.2 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit TUG-UBL1 PF11470.8 CRK29134.1 - 4.6e-26 90.8 0.2 1e-25 89.7 0.2 1.6 1 0 0 1 1 1 1 TUG ubiquitin-like domain RBD PF02196.15 CRK29134.1 - 0.00034 20.6 0.2 0.00075 19.5 0.2 1.6 1 0 0 1 1 1 1 Raf-like Ras-binding domain DUF4294 PF14127.6 CRK29134.1 - 0.007 16.3 0.2 0.021 14.8 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4294) UBX PF00789.20 CRK29134.1 - 0.1 12.8 0.0 0.41 10.9 0.0 2.0 3 0 0 3 3 3 0 UBX domain RA PF00788.23 CRK29134.1 - 0.14 12.8 0.2 0.29 11.8 0.2 1.5 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain Ribosomal_L36e PF01158.18 CRK29135.1 - 4e-42 142.4 5.2 4.5e-42 142.2 5.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e MRP-L28 PF09812.9 CRK29135.1 - 0.0093 16.1 1.9 0.011 15.9 1.9 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 PBS_linker_poly PF00427.21 CRK29135.1 - 0.11 12.5 0.3 0.14 12.2 0.3 1.1 1 0 0 1 1 1 0 Phycobilisome Linker polypeptide DUF2207 PF09972.9 CRK29135.1 - 0.13 10.9 0.0 0.14 10.9 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) AltA1 PF16541.5 CRK29136.1 - 0.0014 19.5 2.4 0.0034 18.2 0.7 2.0 1 1 1 2 2 2 1 Alternaria alternata allergen 1 14-3-3 PF00244.20 CRK29137.1 - 2.4e-38 131.9 0.1 2.6e-38 131.7 0.1 1.0 1 0 0 1 1 1 1 14-3-3 protein Fungal_trans PF04082.18 CRK29139.1 - 2.3e-16 59.6 0.4 6.1e-16 58.2 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain RAG1_imp_bd PF12560.8 CRK29139.1 - 0.08 12.5 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 RAG1 importin binding DJ-1_PfpI PF01965.24 CRK29140.1 - 5.7e-06 26.2 0.0 3e-05 23.9 0.0 2.0 1 1 0 1 1 1 1 DJ-1/PfpI family MFS_1 PF07690.16 CRK29141.1 - 1.5e-39 135.9 32.6 1.5e-39 135.9 32.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK29141.1 - 4.3e-12 45.6 4.3 4.3e-12 45.6 4.3 1.6 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 CRK29141.1 - 1.4e-07 31.2 3.5 1.4e-07 31.2 3.5 2.5 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Tmp39 PF10271.9 CRK29141.1 - 0.051 12.6 0.1 0.083 11.9 0.1 1.2 1 0 0 1 1 1 0 Putative transmembrane protein FMN_dh PF01070.18 CRK29142.1 - 3e-122 408.0 0.5 4.5e-122 407.4 0.5 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Anoctamin PF04547.12 CRK29142.1 - 1.8e-113 379.8 10.1 2.3e-113 379.4 10.1 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Cyt-b5 PF00173.28 CRK29142.1 - 2.8e-21 75.5 0.1 5.5e-21 74.5 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain SH3_9 PF14604.6 CRK29142.1 - 6.2e-14 51.6 0.5 4e-13 49.0 0.1 2.4 2 0 0 2 2 2 1 Variant SH3 domain Glu_synthase PF01645.17 CRK29142.1 - 3.7e-08 32.9 0.1 6.2e-08 32.2 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 CRK29142.1 - 0.001 18.2 0.1 0.0022 17.1 0.1 1.5 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain SH3_1 PF00018.28 CRK29142.1 - 0.0046 16.5 3.3 0.011 15.3 3.3 1.7 1 0 0 1 1 1 1 SH3 domain NMO PF03060.15 CRK29142.1 - 0.038 13.4 0.8 0.085 12.2 0.8 1.5 1 0 0 1 1 1 0 Nitronate monooxygenase SH3_2 PF07653.17 CRK29142.1 - 0.12 12.1 0.3 0.27 10.9 0.3 1.6 1 0 0 1 1 1 0 Variant SH3 domain His_biosynth PF00977.21 CRK29142.1 - 0.19 11.2 1.1 2.7 7.4 0.2 2.2 1 1 1 2 2 2 0 Histidine biosynthesis protein UbiA PF01040.18 CRK29142.1 - 1.6 8.0 12.6 0.42 9.9 0.6 2.7 3 0 0 3 3 3 0 UbiA prenyltransferase family Metallophos PF00149.28 CRK29143.1 - 4.3e-09 37.2 0.0 9.1e-09 36.1 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CRK29143.1 - 0.00055 20.2 2.2 0.003 17.8 0.3 2.6 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain WSC PF01822.19 CRK29144.1 - 1.7e-12 47.3 6.8 1.7e-12 47.3 6.8 2.8 3 0 0 3 3 3 1 WSC domain Glyco_hydro_16 PF00722.21 CRK29144.1 - 1.8e-06 27.6 0.0 9.3e-06 25.2 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 4HBT PF03061.22 CRK29145.1 - 2.1e-12 47.2 0.1 2.8e-12 46.8 0.1 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 CRK29145.1 - 0.00062 20.1 0.1 0.00093 19.5 0.1 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily F-box-like PF12937.7 CRK29146.1 - 0.00011 22.0 0.3 0.0002 21.2 0.3 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CRK29146.1 - 0.0049 16.7 0.1 0.012 15.5 0.1 1.7 1 0 0 1 1 1 1 F-box domain Fungal_trans PF04082.18 CRK29147.1 - 7.6e-68 228.4 0.1 1.1e-67 228.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 CRK29147.1 - 7.1e-06 26.2 10.0 0.00032 21.0 0.7 3.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CRK29147.1 - 0.0024 18.6 7.8 0.05 14.5 0.5 3.4 2 0 0 2 2 2 2 C2H2-type zinc finger Serglycin PF04360.12 CRK29147.1 - 0.0037 17.2 0.5 0.01 15.8 0.5 1.7 1 0 0 1 1 1 1 Serglycin zf-H2C2_2 PF13465.6 CRK29147.1 - 1.1 9.8 11.2 0.39 11.2 1.2 3.5 3 0 0 3 3 3 0 Zinc-finger double domain RhoGAP PF00620.27 CRK29156.1 - 1.1e-11 44.7 0.0 2.2e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain TPR_2 PF07719.17 CRK29158.1 - 3e-07 30.1 6.4 8.6e-05 22.4 0.1 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 CRK29158.1 - 0.00028 20.6 1.9 0.00092 18.9 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 CRK29158.1 - 0.12 13.3 0.2 0.12 13.3 0.2 7.1 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_11 PF13414.6 CRK29158.1 - 0.27 11.0 2.0 3 7.6 0.0 3.0 3 0 0 3 3 3 0 TPR repeat Arrestin_C PF02752.22 CRK29159.1 - 1.3e-11 45.1 0.0 1.9e-09 38.1 0.0 2.3 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CRK29159.1 - 4e-11 43.2 0.0 1.9e-10 41.0 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 CRK29159.1 - 0.00036 20.3 0.0 0.00067 19.4 0.0 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like DUF3425 PF11905.8 CRK29162.1 - 8.2e-15 54.9 0.5 2.1e-14 53.6 0.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 CRK29162.1 - 0.19 11.9 5.1 0.35 11.0 5.1 1.4 1 0 0 1 1 1 0 bZIP transcription factor SUIM_assoc PF16619.5 CRK29162.1 - 7 6.8 12.7 0.15 12.1 1.8 3.3 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 DAO PF01266.24 CRK29164.1 - 7.5e-25 88.3 1.0 1.2e-24 87.5 1.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_4 PF01565.23 CRK29164.1 - 4.2e-22 78.4 0.9 8.8e-22 77.3 0.9 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 CRK29164.1 - 8.9e-10 38.5 0.1 1.8e-09 37.6 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like Sulfate_transp PF00916.20 CRK29167.1 - 2.9e-87 292.9 11.9 3.8e-87 292.5 11.9 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 CRK29167.1 - 2.2e-10 40.2 0.0 4.5e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 CRK29167.1 - 0.0059 16.9 0.0 0.16 12.3 0.0 3.0 3 0 0 3 3 3 1 STAS domain MotB_plug PF13677.6 CRK29167.1 - 0.053 13.1 0.5 0.13 11.8 0.5 1.6 1 0 0 1 1 1 0 Membrane MotB of proton-channel complex MotA/MotB HTH_21 PF13276.6 CRK29167.1 - 0.082 13.1 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 HTH-like domain Cupin_1 PF00190.22 CRK29168.1 - 7.1e-44 149.1 0.0 1e-21 77.2 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 CRK29168.1 - 3.7e-26 90.6 1.6 3.6e-13 49.0 0.2 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 CRK29168.1 - 5.3e-09 35.6 0.0 0.00011 21.8 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 CRK29168.1 - 7e-08 32.5 0.1 0.00059 19.7 0.0 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain MannoseP_isomer PF01050.18 CRK29168.1 - 0.0019 18.1 0.0 0.11 12.4 0.0 2.2 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase ARD PF03079.14 CRK29168.1 - 0.0043 17.2 1.2 0.25 11.5 0.1 2.3 2 0 0 2 2 2 1 ARD/ARD' family cNMP_binding PF00027.29 CRK29168.1 - 0.2 11.7 0.0 1.9 8.6 0.0 2.3 2 0 0 2 2 2 0 Cyclic nucleotide-binding domain Cupin_7 PF12973.7 CRK29168.1 - 0.33 10.9 1.8 0.94 9.4 0.1 2.6 3 1 0 3 3 3 0 ChrR Cupin-like domain eIF-5_eIF-2B PF01873.17 CRK29171.1 - 9.2e-42 141.6 0.6 1.5e-41 140.9 0.6 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 zinc_ribbon_6 PF14599.6 CRK29171.1 - 0.076 13.0 0.7 7.8 6.6 0.1 2.6 2 0 0 2 2 2 0 Zinc-ribbon Lar_restr_allev PF14354.6 CRK29171.1 - 0.16 12.4 1.2 2.6 8.5 1.2 2.6 1 1 0 1 1 1 0 Restriction alleviation protein Lar TF_Zn_Ribbon PF08271.12 CRK29171.1 - 0.94 9.1 3.8 3.1 7.4 3.8 1.8 1 1 0 1 1 1 0 TFIIB zinc-binding Arc_trans_TRASH PF08394.10 CRK29171.1 - 2.3 8.6 8.6 1.8 8.9 0.6 2.5 1 1 1 2 2 2 0 Archaeal TRASH domain zf-HYPF PF07503.12 CRK29171.1 - 4.3 7.2 7.3 2.8 7.8 4.5 2.2 2 1 1 3 3 3 0 HypF finger DUF1654 PF07867.11 CRK29172.1 - 0.18 11.6 1.9 0.25 11.1 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1654) DUF1712 PF08217.11 CRK29173.1 - 4e-13 48.7 0.0 8.2e-11 41.1 0.0 2.7 2 1 0 2 2 2 2 Fungal domain of unknown function (DUF1712) Ank_4 PF13637.6 CRK29174.1 - 0.0034 17.9 0.0 0.037 14.6 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CRK29174.1 - 0.072 13.7 0.0 0.89 10.2 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Ank PF00023.30 CRK29174.1 - 0.12 12.9 0.1 17 6.0 0.0 2.6 2 1 0 2 2 2 0 Ankyrin repeat ICL PF00463.21 CRK29175.1 - 5.7e-278 922.7 0.2 6.9e-278 922.4 0.2 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 CRK29175.1 - 1.8e-11 43.9 1.2 5.6e-11 42.4 0.0 2.2 2 1 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Trehalase PF01204.18 CRK29176.1 - 4.2e-192 639.5 0.0 4.9e-192 639.3 0.0 1.0 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 CRK29176.1 - 1e-16 60.3 2.5 1.7e-16 59.6 2.5 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain PBP PF01161.20 CRK29180.1 - 1.4e-12 48.0 0.1 2.3e-12 47.4 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Pyr_redox_2 PF07992.14 CRK29181.1 - 2.2e-30 105.9 1.1 2.6e-30 105.7 1.1 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CRK29181.1 - 1.2e-09 38.5 2.7 8.8e-09 35.8 1.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CRK29181.1 - 5.3e-05 23.3 3.8 0.31 11.0 0.0 3.4 4 0 0 4 4 4 2 FAD-NAD(P)-binding K_oxygenase PF13434.6 CRK29181.1 - 0.00059 19.1 0.5 0.043 12.9 0.1 2.9 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 CRK29181.1 - 0.015 14.9 11.7 0.39 10.3 0.1 3.7 1 1 1 4 4 4 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 CRK29181.1 - 0.015 14.4 0.5 0.037 13.1 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.14 CRK29181.1 - 0.24 10.0 1.7 30 3.2 0.0 3.3 3 1 1 4 4 4 0 HI0933-like protein TrkA_N PF02254.18 CRK29181.1 - 0.48 10.7 3.0 7.5 6.9 0.0 3.3 2 2 0 2 2 2 0 TrkA-N domain GIDA PF01134.22 CRK29181.1 - 1.2 8.1 6.2 2.5 7.1 0.0 2.9 2 1 0 3 3 3 0 Glucose inhibited division protein A cobW PF02492.19 CRK29184.1 - 1.4e-34 119.2 0.0 2.6e-34 118.3 0.0 1.5 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 CRK29184.1 - 0.00021 21.2 0.0 0.00042 20.2 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.6 CRK29184.1 - 0.0082 16.4 0.0 0.028 14.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 CRK29184.1 - 0.016 14.9 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase CobW_C PF07683.14 CRK29184.1 - 0.039 13.9 0.2 0.61 10.0 0.0 2.8 2 2 0 2 2 2 0 Cobalamin synthesis protein cobW C-terminal domain AAA_29 PF13555.6 CRK29184.1 - 0.043 13.6 1.1 0.32 10.8 0.1 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain NTPase_1 PF03266.15 CRK29184.1 - 0.044 13.7 0.0 0.11 12.5 0.0 1.6 2 0 0 2 2 2 0 NTPase DUF2075 PF09848.9 CRK29184.1 - 0.064 12.5 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TrwB_AAD_bind PF10412.9 CRK29184.1 - 0.071 12.0 0.0 0.16 10.9 0.0 1.5 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_18 PF13238.6 CRK29184.1 - 0.077 13.5 0.4 0.65 10.5 0.4 2.4 1 1 0 1 1 1 0 AAA domain FlgT_M PF16539.5 CRK29184.1 - 0.12 12.6 0.1 0.27 11.3 0.0 1.7 2 0 0 2 2 2 0 Flagellar assembly protein T, middle domain DUF463 PF04317.12 CRK29184.1 - 0.13 11.2 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 YcjX-like family, DUF463 tRNA-synt_1 PF00133.22 CRK29185.1 - 6.1e-52 176.7 0.0 7.6e-19 67.4 0.1 6.1 2 1 3 5 5 5 5 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 CRK29185.1 - 7.2e-42 143.0 0.0 1.2e-41 142.2 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 CRK29185.1 - 5.9e-28 97.7 0.0 1.1e-18 67.2 0.0 4.5 3 2 1 4 4 4 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 CRK29185.1 - 7e-13 48.8 0.0 1.3e-12 47.9 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA Zn-ribbon_8 PF09723.10 CRK29185.1 - 0.076 13.1 2.5 0.64 10.2 0.2 2.9 3 0 0 3 3 3 0 Zinc ribbon domain zf-ribbon_3 PF13248.6 CRK29185.1 - 1.4 8.5 2.9 15 5.2 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain MTHFR PF02219.17 CRK29186.1 - 1.5e-99 332.9 0.0 2.1e-99 332.5 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Sorting_nexin PF03700.13 CRK29187.1 - 0.0047 17.5 5.1 0.016 15.7 5.1 2.0 1 1 0 1 1 1 1 Sorting nexin, N-terminal domain GST_C_3 PF14497.6 CRK29188.1 - 5.2e-33 113.2 0.1 1.1e-32 112.2 0.1 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CRK29188.1 - 4.2e-06 26.9 0.1 1.1e-05 25.5 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CRK29188.1 - 4.7e-05 23.3 0.0 7.7e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF1508 PF07411.12 CRK29188.1 - 0.0044 16.8 0.1 0.014 15.2 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1508) Tannase PF07519.11 CRK29190.1 - 4.1e-95 319.4 0.6 6.2e-48 163.9 0.0 2.1 1 1 1 2 2 2 2 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 CRK29190.1 - 0.026 13.8 0.0 0.064 12.5 0.0 1.5 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Sugar_tr PF00083.24 CRK29191.1 - 3.3e-115 385.5 20.7 3.9e-115 385.3 20.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK29191.1 - 2.1e-24 86.1 38.9 1.3e-19 70.3 12.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5331 PF17265.2 CRK29192.1 - 0.042 13.6 0.0 0.059 13.1 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5331) SPATIAL PF15256.6 CRK29193.1 - 0.41 11.0 5.9 0.049 14.0 1.2 1.9 2 0 0 2 2 2 0 SPATIAL SKG6 PF08693.10 CRK29193.1 - 0.74 9.3 3.3 1.6 8.2 3.3 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain PGF-CTERM PF18204.1 CRK29193.1 - 2.5 8.2 4.6 4.3 7.4 4.6 1.4 1 0 0 1 1 1 0 PGF-CTERM motif Glyco_hydro_7 PF00840.20 CRK29194.1 - 1.9e-182 606.9 10.9 2.3e-182 606.6 10.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CBM_1 PF00734.18 CRK29194.1 - 5.9e-13 48.5 15.5 5.9e-13 48.5 15.5 4.1 3 1 0 3 3 3 1 Fungal cellulose binding domain Glyco_hydr_30_2 PF14587.6 CRK29195.1 - 2.7e-24 86.4 9.4 1.6e-08 34.6 0.0 3.2 2 1 1 3 3 3 3 O-Glycosyl hydrolase family 30 Glyco_hydro_30 PF02055.16 CRK29195.1 - 5.3e-20 71.7 2.3 4.6e-10 39.0 0.3 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_59 PF02057.15 CRK29195.1 - 3.9e-15 55.8 9.7 1.4e-08 34.3 0.4 2.5 2 1 0 2 2 2 2 Glycosyl hydrolase family 59 Glyco_hydro_30C PF17189.4 CRK29195.1 - 5.1e-09 36.2 0.0 1.2e-08 35.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain DUF5390 PF17365.2 CRK29195.1 - 0.033 14.5 0.0 11 6.3 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5390) DUF829 PF05705.14 CRK29195.1 - 0.043 13.7 0.5 9.5 6.0 0.0 2.3 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF829) ABC_tran PF00005.27 CRK29196.1 - 1.3e-26 93.8 0.0 2e-26 93.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 CRK29196.1 - 3.9e-13 49.3 4.6 7e-13 48.5 4.6 1.4 1 0 0 1 1 1 1 ABC-2 type transporter RsgA_GTPase PF03193.16 CRK29196.1 - 0.00036 20.5 0.3 0.00068 19.6 0.3 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 CRK29196.1 - 0.0047 17.3 0.0 0.037 14.4 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 CRK29196.1 - 0.0081 16.2 0.3 0.016 15.3 0.3 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_25 PF13481.6 CRK29196.1 - 0.0084 15.7 0.1 0.016 14.8 0.1 1.4 1 0 0 1 1 1 1 AAA domain Dynamin_N PF00350.23 CRK29196.1 - 0.019 15.1 0.0 0.032 14.3 0.0 1.3 1 0 0 1 1 1 0 Dynamin family AAA_29 PF13555.6 CRK29196.1 - 0.045 13.5 0.5 0.098 12.4 0.5 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SSE PF00437.20 CRK29196.1 - 0.075 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein IIGP PF05049.13 CRK29196.1 - 0.08 12.0 0.2 0.12 11.4 0.2 1.1 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) MeaB PF03308.16 CRK29196.1 - 0.086 11.8 1.1 0.14 11.1 0.1 1.7 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF87 PF01935.17 CRK29196.1 - 0.47 10.5 2.3 0.81 9.7 2.3 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain ABC2_membrane_3 PF12698.7 CRK29196.1 - 1.4 7.9 8.4 2.4 7.2 8.4 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein ATP_bind_1 PF03029.17 CRK29196.1 - 1.9 8.2 4.2 0.7 9.6 1.4 1.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Aa_trans PF01490.18 CRK29197.1 - 4.3e-83 279.3 23.0 5.1e-83 279.1 23.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Cutinase PF01083.22 CRK29198.1 - 5.2e-43 147.1 2.2 1.8e-42 145.3 2.2 1.8 1 1 0 1 1 1 1 Cutinase PE-PPE PF08237.11 CRK29198.1 - 0.0011 18.5 0.1 0.0017 18.0 0.1 1.4 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.11 CRK29198.1 - 0.0033 17.3 0.0 0.0052 16.7 0.0 1.3 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) Abhydrolase_3 PF07859.13 CRK29198.1 - 0.081 12.8 0.1 0.19 11.6 0.1 1.7 1 0 0 1 1 1 0 alpha/beta hydrolase fold FAD_binding_2 PF00890.24 CRK29199.1 - 1.4e-94 317.6 1.6 1.6e-94 317.4 1.6 1.0 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 CRK29199.1 - 3.7e-07 29.7 0.3 9.4e-07 28.4 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 CRK29199.1 - 3.9e-07 30.2 0.2 1.6e-06 28.2 0.2 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CRK29199.1 - 2.4e-06 27.4 1.1 2.9e-05 23.8 0.0 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CRK29199.1 - 2.7e-05 23.5 0.0 0.01 15.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CRK29199.1 - 0.0003 20.3 0.0 0.00052 19.5 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 CRK29199.1 - 0.00044 19.5 1.3 0.001 18.3 0.1 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 CRK29199.1 - 0.0038 16.0 3.1 0.052 12.2 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 CRK29199.1 - 0.007 15.6 0.1 0.014 14.6 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 CRK29199.1 - 0.053 12.8 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Smr PF01713.21 CRK29201.1 - 3e-09 37.1 0.2 4.1e-09 36.7 0.2 1.3 1 0 0 1 1 1 1 Smr domain DUF1771 PF08590.10 CRK29201.1 - 0.18 12.2 0.8 0.44 10.9 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1771) G-alpha PF00503.20 CRK29202.1 - 1.1e-124 416.2 2.5 1.3e-124 415.9 2.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CRK29202.1 - 3.7e-15 55.8 2.0 2.8e-10 39.9 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.20 CRK29202.1 - 8.5e-05 22.3 0.0 0.00036 20.3 0.0 1.9 2 0 0 2 2 2 1 CHC2 zinc finger Gtr1_RagA PF04670.12 CRK29202.1 - 0.0019 17.6 2.9 0.11 11.9 0.0 2.7 2 1 1 3 3 3 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.6 CRK29202.1 - 0.014 15.1 0.0 0.033 13.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 CRK29202.1 - 0.024 14.9 0.2 2.4 8.4 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MCM PF00493.23 CRK29202.1 - 0.058 12.5 0.1 0.11 11.6 0.1 1.5 1 1 0 1 1 1 0 MCM P-loop domain GTP_EFTU PF00009.27 CRK29202.1 - 0.12 11.9 0.0 1.6 8.2 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.18 CRK29202.1 - 0.12 11.7 0.0 0.28 10.5 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 CRK29202.1 - 0.13 12.3 0.1 8.8 6.5 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase D123 PF07065.14 CRK29203.1 - 5.1e-112 374.0 0.0 1.2e-111 372.8 0.0 1.7 1 0 0 1 1 1 1 D123 DUF3716 PF12511.8 CRK29203.1 - 2e-15 56.5 10.4 3.7e-15 55.7 10.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) SelK_SelG PF10961.8 CRK29203.1 - 1.7 9.3 3.9 12 6.6 0.4 2.8 2 0 0 2 2 2 0 Selenoprotein SelK_SelG cwf21 PF08312.12 CRK29204.1 - 3.9e-17 62.1 15.8 3.9e-17 62.1 15.8 2.4 2 0 0 2 2 2 1 cwf21 domain GvpG PF05120.12 CRK29204.1 - 0.015 15.3 10.0 0.06 13.4 2.8 2.4 2 1 0 2 2 2 0 Gas vesicle protein G NDUFA12 PF05071.16 CRK29205.1 - 2.9e-10 40.8 2.9 2.9e-10 40.8 0.2 2.0 2 0 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 CH PF00307.31 CRK29206.1 - 6.5e-14 52.0 0.0 1e-13 51.4 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 CRK29206.1 - 0.16 11.8 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 CAMSAP CH domain Hce2 PF14856.6 CRK29207.1 - 1.7e-13 50.7 0.0 3.8e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor SesA PF17107.5 CRK29207.1 - 0.00068 19.8 0.3 0.0013 18.9 0.3 1.5 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Helo_like_N PF17111.5 CRK29207.1 - 0.0027 17.1 0.1 0.0082 15.5 0.1 1.8 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins HeLo PF14479.6 CRK29207.1 - 0.04 13.8 0.0 0.13 12.1 0.0 1.8 1 1 0 1 1 1 0 Prion-inhibition and propagation Laminin_II PF06009.12 CRK29207.1 - 0.13 12.3 0.0 5.7 7.0 0.1 2.3 2 0 0 2 2 2 0 Laminin Domain II DUF4449 PF14613.6 CRK29208.1 - 1.6e-70 236.4 5.2 1.6e-70 236.4 5.2 2.4 2 1 1 3 3 3 1 Protein of unknown function (DUF4449) JHBP PF06585.11 CRK29208.1 - 0.041 13.1 3.2 0.063 12.4 1.8 2.1 2 0 0 2 2 2 0 Haemolymph juvenile hormone binding protein (JHBP) TPR_6 PF13174.6 CRK29208.1 - 0.56 11.0 3.4 1.2e+02 3.6 0.0 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat YlqD PF11068.8 CRK29208.1 - 2.4 8.6 15.9 0.057 13.8 6.4 2.7 2 0 0 2 2 2 0 YlqD protein HisKA_3 PF07730.13 CRK29208.1 - 2.5 8.7 5.1 11 6.6 0.7 3.9 3 0 0 3 3 3 0 Histidine kinase APH PF01636.23 CRK29209.1 - 1.2e-05 25.4 0.5 1.8e-05 24.8 0.1 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.11 CRK29209.1 - 0.00036 19.5 0.0 0.00052 19.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.20 CRK29209.1 - 0.032 13.5 0.0 0.055 12.8 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase APH PF01636.23 CRK29210.1 - 1.6e-14 54.4 0.0 2.1e-13 50.7 0.0 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 CRK29210.1 - 0.0011 18.0 0.0 0.0028 16.6 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) EcKinase PF02958.20 CRK29210.1 - 0.099 11.9 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase DNA_ligase_A_M PF01068.21 CRK29212.1 - 3.2e-45 154.3 0.0 8.1e-45 153.0 0.0 1.7 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 CRK29212.1 - 9.7e-42 143.2 0.0 2e-41 142.2 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus RNA_ligase PF09414.10 CRK29212.1 - 5.6e-19 69.0 0.0 1.1e-18 68.1 0.0 1.5 1 0 0 1 1 1 1 RNA ligase BRCT_2 PF16589.5 CRK29212.1 - 2.5e-14 53.4 0.0 2.2e-08 34.4 0.0 2.4 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain DNA_ligase_A_C PF04679.15 CRK29212.1 - 1e-13 51.7 0.3 1.5e-12 48.0 0.0 2.6 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region BRCT PF00533.26 CRK29212.1 - 3e-07 30.7 0.0 7.6e-06 26.2 0.0 2.6 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 CRK29212.1 - 0.00037 20.7 0.0 1.4 9.3 0.0 2.5 2 0 0 2 2 2 2 DNA ligase 3 BRCT domain DNA_ligase_IV PF11411.8 CRK29212.1 - 0.0017 18.4 0.0 0.0039 17.3 0.0 1.6 1 0 0 1 1 1 1 DNA ligase IV mRNA_cap_enzyme PF01331.19 CRK29212.1 - 0.02 14.8 0.2 0.84 9.4 0.0 2.6 1 1 1 2 2 2 0 mRNA capping enzyme, catalytic domain UPRTase PF14681.6 CRK29213.1 - 1.3e-73 246.9 0.0 1.8e-73 246.4 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 CRK29213.1 - 0.0022 17.5 0.5 0.0091 15.5 0.5 1.9 1 1 0 1 1 1 1 Phosphoribosyl transferase domain TMP-TENI PF02581.17 CRK29213.1 - 0.085 12.2 0.9 0.9 8.8 0.7 2.1 2 0 0 2 2 2 0 Thiamine monophosphate synthase CRCB PF02537.15 CRK29214.1 - 1.3e-38 131.2 10.5 8.1e-23 80.5 4.8 2.3 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) DUF4360 PF14273.6 CRK29215.1 - 2e-61 207.0 1.9 2.3e-61 206.8 1.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) OmdA PF13376.6 CRK29216.1 - 2e-19 69.3 1.0 2e-19 69.3 1.0 2.4 3 0 0 3 3 3 1 Bacteriocin-protection, YdeI or OmpD-Associated CHZ PF09649.10 CRK29216.1 - 7.2 6.2 9.7 11 5.6 0.1 3.7 4 0 0 4 4 4 0 Histone chaperone domain CHZ p450 PF00067.22 CRK29218.1 - 3.1e-52 177.9 0.0 4.6e-52 177.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 TMEM213 PF15192.6 CRK29219.1 - 0.0096 15.9 0.1 0.11 12.5 0.2 2.4 2 0 0 2 2 2 1 TMEM213 family KRE1 PF17056.5 CRK29219.1 - 0.15 11.8 1.9 0.35 10.6 0.1 2.3 2 0 0 2 2 2 0 Killer toxin-resistance protein 1 AA_permease_2 PF13520.6 CRK29220.1 - 2.6e-88 296.7 37.4 3.1e-88 296.5 37.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CRK29220.1 - 9.2e-20 70.7 30.8 1.3e-19 70.2 30.8 1.1 1 0 0 1 1 1 1 Amino acid permease FAD_binding_4 PF01565.23 CRK29222.1 - 1.8e-20 73.1 0.3 2.6e-20 72.6 0.3 1.1 1 0 0 1 1 1 1 FAD binding domain RNA_polI_A34 PF08208.11 CRK29224.1 - 2.2e-43 148.8 26.4 2.2e-43 148.8 26.4 5.3 2 2 1 3 3 3 1 DNA-directed RNA polymerase I subunit RPA34.5 CLP1_P PF16575.5 CRK29225.1 - 6.4e-36 123.9 0.0 9.4e-36 123.4 0.0 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_33 PF13671.6 CRK29225.1 - 0.088 13.0 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Fungal_trans PF04082.18 CRK29226.1 - 6.6e-06 25.3 0.1 1.1e-05 24.6 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain YbbR PF07949.12 CRK29226.1 - 0.03 14.7 0.3 0.14 12.5 0.0 2.2 3 0 0 3 3 3 0 YbbR-like protein ADH_zinc_N_2 PF13602.6 CRK29227.1 - 1.7e-24 87.4 0.1 2.5e-24 86.8 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 CRK29227.1 - 1.6e-14 54.0 0.2 2.5e-14 53.4 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CRK29227.1 - 4.9e-07 29.6 0.5 3e-06 27.1 0.5 2.4 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Sugar_tr PF00083.24 CRK29228.1 - 1.4e-72 245.0 23.5 1.6e-72 244.8 23.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK29228.1 - 7.6e-17 61.3 50.8 3.3e-15 55.9 38.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ATP-synt_C PF00137.21 CRK29228.1 - 0.16 12.3 4.8 11 6.5 0.4 3.3 2 1 0 2 2 2 0 ATP synthase subunit C Zn_clus PF00172.18 CRK29229.1 - 0.00047 20.2 3.2 0.00096 19.2 3.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 CRK29229.1 - 0.0039 16.3 0.9 0.008 15.2 0.9 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain MgtE_N PF03448.17 CRK29230.1 - 0.057 14.0 0.1 0.075 13.6 0.1 1.2 1 0 0 1 1 1 0 MgtE intracellular N domain Hum_adeno_E3A PF05393.11 CRK29231.1 - 0.086 12.8 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein Tetraspanin PF00335.20 CRK29231.1 - 0.12 12.0 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Tetraspanin family Abhydrolase_9_N PF15420.6 CRK29231.1 - 0.15 12.0 0.0 0.22 11.5 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus TMEM154 PF15102.6 CRK29231.1 - 0.2 11.6 0.0 0.5 10.3 0.0 1.6 2 0 0 2 2 2 0 TMEM154 protein family Lgl_C PF08596.10 CRK29232.1 - 3.6e-115 384.8 0.0 5.1e-115 384.3 0.0 1.2 1 0 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.32 CRK29232.1 - 1.9e-05 25.3 2.3 0.03 15.2 0.1 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK29232.1 - 2.5e-05 24.5 0.0 3.1 8.2 0.0 4.9 5 1 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain CorA PF01544.18 CRK29233.1 - 5.5e-10 39.0 0.0 1e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Methyltransf_31 PF13847.6 CRK29234.1 - 5.7e-13 48.9 0.0 8.5e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK29234.1 - 1.9e-12 47.7 0.0 3.5e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CRK29234.1 - 4.2e-12 46.2 0.0 6.8e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CRK29234.1 - 6e-12 46.1 0.0 1.1e-11 45.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK29234.1 - 8.4e-10 39.3 0.1 2.1e-09 38.0 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 CRK29234.1 - 4.3e-08 33.3 0.0 5.6e-07 29.7 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain PrmA PF06325.13 CRK29234.1 - 3.1e-07 30.1 0.0 4.7e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) DREV PF05219.12 CRK29234.1 - 4.8e-06 25.9 0.0 1.5e-05 24.3 0.0 1.7 1 1 0 1 1 1 1 DREV methyltransferase MTS PF05175.14 CRK29234.1 - 1.7e-05 24.4 0.0 3e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 CRK29234.1 - 8.1e-05 22.1 0.0 0.00012 21.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 CRK29234.1 - 0.00013 21.4 0.0 0.00016 21.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase GidB PF02527.15 CRK29234.1 - 0.0003 20.2 0.0 0.00076 18.8 0.0 1.6 1 1 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_18 PF12847.7 CRK29234.1 - 0.0035 17.3 0.0 0.0083 16.1 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain UPF0146 PF03686.13 CRK29234.1 - 0.0047 16.8 0.0 0.0074 16.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0146) 3HCDH_N PF02737.18 CRK29234.1 - 0.0068 16.3 0.1 3.2 7.6 0.0 2.2 1 1 1 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short PF00106.25 CRK29234.1 - 0.0095 15.4 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase PCMT PF01135.19 CRK29234.1 - 0.013 15.2 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 CRK29234.1 - 0.014 15.2 0.0 0.022 14.5 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase TehB PF03848.14 CRK29234.1 - 0.03 13.7 0.0 0.049 13.0 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB adh_short_C2 PF13561.6 CRK29234.1 - 0.043 13.4 0.0 0.069 12.7 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase MetW PF07021.12 CRK29234.1 - 0.11 12.1 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Hydrophobin_2 PF06766.11 CRK29235.1 - 2.5e-17 62.5 8.1 3.4e-17 62.2 8.1 1.2 1 0 0 1 1 1 1 Fungal hydrophobin Melibiase_2 PF16499.5 CRK29236.1 - 5.1e-50 170.2 8.2 1.5e-35 122.8 2.4 2.2 2 0 0 2 2 2 2 Alpha galactosidase A Melibiase_C PF17801.1 CRK29236.1 - 6.6e-12 45.3 1.6 5.4e-11 42.4 0.0 2.7 3 0 0 3 3 3 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 CRK29236.1 - 2.6e-05 23.4 0.0 4.7e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Melibiase HET PF06985.11 CRK29237.1 - 6.3e-20 72.0 0.0 1.5e-19 70.8 0.0 1.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Peptidase_S8 PF00082.22 CRK29238.1 - 1.2e-39 136.3 3.3 1.9e-39 135.7 3.3 1.3 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 CRK29238.1 - 0.014 16.1 0.0 0.028 15.1 0.0 1.5 1 0 0 1 1 1 0 Fn3-like domain Ank_2 PF12796.7 CRK29240.1 - 3.5e-32 110.8 0.1 1.6e-10 41.4 0.1 5.3 2 2 3 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CRK29240.1 - 2.8e-26 91.5 1.9 1.7e-06 28.5 0.1 7.2 3 3 3 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 CRK29240.1 - 2.8e-24 84.8 0.7 4.4e-09 36.4 0.1 5.7 4 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 CRK29240.1 - 9.3e-22 74.8 2.5 0.0013 19.0 0.1 8.1 9 0 0 9 9 9 5 Ankyrin repeat Ank PF00023.30 CRK29240.1 - 4.8e-17 61.6 0.4 1.5e-05 25.2 0.1 6.9 7 0 0 7 7 7 3 Ankyrin repeat Helo_like_N PF17111.5 CRK29240.1 - 5.2e-09 35.8 0.0 8e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins SesA PF17107.5 CRK29240.1 - 0.056 13.6 0.0 0.21 11.8 0.0 2.0 1 1 1 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases PGM1_C PF18105.1 CRK29240.1 - 0.059 12.9 0.0 0.57 9.7 0.0 2.4 2 0 0 2 2 2 0 PGM1 C-terminal domain Glyco_transf_20 PF00982.21 CRK29243.1 - 1.2e-143 479.3 0.0 1.6e-143 478.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 CRK29243.1 - 1.5e-72 243.5 0.0 2.8e-72 242.6 0.0 1.5 1 0 0 1 1 1 1 Trehalose-phosphatase COG5 PF10392.9 CRK29244.1 - 3.2e-39 134.1 0.8 1e-38 132.5 0.6 2.0 2 0 0 2 2 2 1 Golgi transport complex subunit 5 BTB PF00651.31 CRK29244.1 - 7.5e-12 45.5 0.0 2.1e-11 44.0 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain SRX PF09201.10 CRK29244.1 - 0.11 12.3 0.0 0.34 10.7 0.0 1.8 2 0 0 2 2 2 0 SRX, signal recognition particle receptor alpha subunit DUF1722 PF08349.11 CRK29244.1 - 0.12 12.7 0.0 0.31 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) DUF2434 PF10361.9 CRK29245.1 - 9.9e-137 454.8 5.0 1.2e-136 454.4 5.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2434) ABC2_membrane_2 PF12679.7 CRK29245.1 - 0.11 11.8 0.7 0.24 10.6 0.0 2.0 3 0 0 3 3 3 0 ABC-2 family transporter protein ARS2 PF04959.13 CRK29245.1 - 0.5 10.7 2.0 0.85 10.0 2.0 1.2 1 0 0 1 1 1 0 Arsenite-resistance protein 2 3-dmu-9_3-mt PF06983.13 CRK29246.1 - 3e-45 153.5 0.1 4.7e-45 152.9 0.1 1.3 1 0 0 1 1 1 1 3-demethylubiquinone-9 3-methyltransferase zf-MYND PF01753.18 CRK29248.1 - 3.7e-05 23.7 32.8 0.00058 19.9 10.2 2.8 2 0 0 2 2 2 2 MYND finger zf-H2C2_2 PF13465.6 CRK29248.1 - 0.00098 19.4 3.8 0.00098 19.4 3.8 2.9 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.26 CRK29248.1 - 0.0095 16.4 1.6 0.0095 16.4 1.6 3.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type AtuA PF07287.11 CRK29249.1 - 2e-125 418.2 0.1 2.7e-125 417.7 0.1 1.2 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA HET PF06985.11 CRK29249.1 - 1.7e-30 106.3 0.0 5.3e-30 104.7 0.0 1.9 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Polysacc_deac_1 PF01522.21 CRK29250.1 - 1.2e-26 93.0 0.0 1.6e-26 92.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 CRK29250.1 - 0.036 13.3 0.0 0.042 13.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 Aminotran_5 PF00266.19 CRK29253.1 - 2.5e-31 109.0 0.0 7.9e-31 107.3 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class-V Acetyltransf_1 PF00583.25 CRK29254.1 - 1.4e-08 34.9 0.0 2.1e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CRK29254.1 - 2.4e-07 30.8 0.0 3.2e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CRK29254.1 - 1.4e-05 25.4 0.0 2.3e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF4590 PF15257.6 CRK29254.1 - 0.024 14.5 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4590) Esterase PF00756.20 CRK29256.1 - 5.7e-16 58.9 0.0 7.6e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 CRK29256.1 - 9.9e-05 21.9 0.0 0.0017 17.9 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 CRK29256.1 - 0.0003 20.1 0.0 0.00042 19.7 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CRK29256.1 - 0.0068 17.0 0.0 0.013 16.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_8 PF06259.12 CRK29256.1 - 0.11 12.1 0.0 0.25 11.0 0.0 1.6 1 1 1 2 2 2 0 Alpha/beta hydrolase Glyco_hydro_61 PF03443.14 CRK29258.1 - 6.7e-67 225.4 0.0 8.4e-67 225.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NPCBM_assoc PF10633.9 CRK29258.1 - 0.037 14.3 0.1 0.35 11.2 0.0 2.3 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Fungal_trans PF04082.18 CRK29259.1 - 9.4e-12 44.5 0.0 1.6e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK29259.1 - 9.9e-06 25.6 8.9 1.7e-05 24.8 8.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3235 PF11574.8 CRK29259.1 - 0.025 15.4 0.1 0.055 14.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3235) MAGP PF05507.11 CRK29259.1 - 0.27 11.6 1.2 0.6 10.5 1.2 1.5 1 0 0 1 1 1 0 Microfibril-associated glycoprotein (MAGP) Sel1 PF08238.12 CRK29265.1 - 1.1e-16 60.9 26.3 5.6e-07 30.0 0.1 7.5 7 0 0 7 7 7 5 Sel1 repeat CSN8_PSD8_EIF3K PF10075.9 CRK29267.1 - 9.9e-19 67.7 0.0 1.7e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 CRK29267.1 - 0.063 12.7 0.0 0.09 12.1 0.0 1.3 1 0 0 1 1 1 0 SAC3/GANP family Coatomer_WDAD PF04053.14 CRK29269.1 - 1.5e-114 383.5 1.1 2.6e-114 382.7 1.1 1.3 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 CRK29269.1 - 8.1e-29 99.3 10.3 2.8e-08 34.3 0.4 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK29269.1 - 4.6e-05 23.6 0.6 3 8.2 0.0 5.9 1 1 6 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 CRK29269.1 - 0.037 13.9 0.0 0.23 11.3 0.0 2.1 1 1 1 2 2 2 0 Region in Clathrin and VPS Nup160 PF11715.8 CRK29269.1 - 0.28 9.8 3.7 1.7 7.2 0.4 2.8 1 1 1 3 3 3 0 Nucleoporin Nup120/160 Glyco_transf_24 PF18404.1 CRK29271.1 - 4.7e-147 488.5 2.2 6.8e-147 488.0 2.2 1.2 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 CRK29271.1 - 8.1e-69 232.4 0.0 2e-68 231.1 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_15 PF18403.1 CRK29271.1 - 3e-59 200.5 0.0 1.4e-53 182.0 0.0 2.8 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_13 PF18401.1 CRK29271.1 - 7.3e-45 152.2 0.2 6.7e-43 145.9 0.2 3.2 3 0 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_12 PF18400.1 CRK29271.1 - 7e-44 150.0 0.1 1.8e-43 148.6 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 CRK29271.1 - 2e-41 140.5 0.0 3.9e-41 139.6 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.20 CRK29271.1 - 8.1e-05 22.3 0.1 0.00019 21.1 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 8 SNF2_N PF00176.23 CRK29274.1 - 6e-60 202.8 0.0 1.2e-59 201.9 0.0 1.4 1 1 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.10 CRK29274.1 - 2.1e-53 181.2 0.5 9.9e-53 179.0 0.8 1.9 2 0 0 2 2 2 1 Rad54 N terminal Helicase_C PF00271.31 CRK29274.1 - 4.8e-16 59.1 0.0 1.3e-15 57.6 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CRK29274.1 - 1.6e-08 34.7 0.0 3.1e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 CRK29274.1 - 0.0016 17.7 0.0 0.0098 15.1 0.0 2.0 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 CRK29274.1 - 0.031 13.9 0.0 0.067 12.9 0.0 1.5 1 0 0 1 1 1 0 SWI2/SNF2 ATPase Form-deh_trans PF09163.11 CRK29275.1 - 0.15 11.9 1.6 4.8 7.0 0.1 2.5 2 1 0 2 2 2 0 Formate dehydrogenase N, transmembrane Mito_carr PF00153.27 CRK29277.1 - 1.4e-45 153.2 5.6 2.4e-19 69.0 0.1 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein Pyr_redox_2 PF07992.14 CRK29277.1 - 1e-19 70.9 0.5 1.8e-19 70.1 0.5 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CRK29277.1 - 4.5e-06 26.7 2.1 0.015 15.3 0.1 3.1 3 0 0 3 3 3 2 FAD-NAD(P)-binding DAO PF01266.24 CRK29277.1 - 2.7e-05 23.9 2.6 0.00022 21.0 0.6 2.5 1 1 1 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 CRK29277.1 - 0.00022 20.4 0.4 0.15 11.1 0.2 2.3 1 1 1 2 2 2 2 Lycopene cyclase protein FAD_binding_3 PF01494.19 CRK29277.1 - 0.00023 20.5 0.0 0.00046 19.5 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 CRK29277.1 - 0.00032 20.9 0.6 0.0012 19.0 0.2 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CRK29277.1 - 0.00035 19.9 0.0 0.00066 19.0 0.0 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 CRK29277.1 - 0.0018 17.0 0.0 0.024 13.3 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein Glu_dehyd_C PF16912.5 CRK29277.1 - 0.0024 17.4 0.1 0.29 10.6 0.0 2.6 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus Pyr_redox_3 PF13738.6 CRK29277.1 - 0.0031 16.8 0.2 0.82 8.9 0.1 2.9 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CRK29277.1 - 0.013 14.6 0.2 1.2 8.1 0.2 2.3 1 1 1 2 2 2 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 CRK29277.1 - 0.03 13.2 0.1 0.048 12.5 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.27 CRK29277.1 - 0.043 14.4 0.3 7.2 7.2 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 CRK29277.1 - 0.08 12.2 0.8 0.41 9.9 0.0 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain RTA1 PF04479.13 CRK29280.1 - 1.7e-38 132.3 2.4 2.4e-38 131.8 2.4 1.2 1 0 0 1 1 1 1 RTA1 like protein FmdA_AmdA PF03069.15 CRK29283.1 - 2.3e-178 592.8 0.0 2.6e-178 592.6 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family OTU PF02338.19 CRK29285.1 - 0.00029 21.3 0.0 0.00052 20.5 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease Bromodomain PF00439.25 CRK29287.1 - 2.9e-49 165.1 6.0 5.1e-19 68.1 0.2 3.4 3 0 0 3 3 3 3 Bromodomain BAH PF01426.18 CRK29287.1 - 3.1e-20 72.2 1.9 4e-20 71.9 0.4 2.0 2 0 0 2 2 2 1 BAH domain RNA_pol_3_Rpc31 PF11705.8 CRK29287.1 - 0.0048 17.2 3.6 0.0048 17.2 3.6 3.5 3 0 0 3 3 3 1 DNA-directed RNA polymerase III subunit Rpc31 DUF1658 PF07871.11 CRK29287.1 - 0.18 11.8 1.2 28 4.9 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1658) BUD22 PF09073.10 CRK29287.1 - 7.3 5.8 31.9 0.18 11.1 11.1 2.4 2 0 0 2 2 2 0 BUD22 Importin_rep_4 PF18808.1 CRK29288.1 - 3.7e-31 107.3 2.2 3.7e-31 107.3 2.2 3.7 3 0 0 3 3 2 1 Importin repeat PAS_9 PF13426.7 CRK29288.1 - 1.5e-24 86.3 0.0 3e-16 59.6 0.0 4.0 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.12 CRK29288.1 - 2.1e-19 69.6 0.0 1.7e-11 44.3 0.0 3.9 3 0 0 3 3 3 3 PAS fold HEAT_EZ PF13513.6 CRK29288.1 - 5.7e-19 68.2 10.4 2.5e-10 40.6 0.1 7.2 5 1 2 7 7 7 3 HEAT-like repeat HEAT_2 PF13646.6 CRK29288.1 - 4.6e-17 62.2 12.7 2.6e-07 30.9 0.1 8.0 3 3 4 7 7 7 3 HEAT repeats HEAT PF02985.22 CRK29288.1 - 4.4e-16 57.6 13.5 0.0059 16.8 0.0 10.3 12 0 0 12 12 9 4 HEAT repeat GATA PF00320.27 CRK29288.1 - 1.2e-14 53.6 8.9 2.2e-14 52.7 8.9 1.5 1 0 0 1 1 1 1 GATA zinc finger PAS PF00989.25 CRK29288.1 - 1.2e-14 54.2 0.0 2.1e-05 24.5 0.0 4.2 3 1 0 3 3 3 3 PAS fold Importin_rep_6 PF18829.1 CRK29288.1 - 6.4e-13 48.8 1.7 1.7e-12 47.4 0.2 2.6 3 0 0 3 3 1 1 Importin repeat 6 Vac14_Fab1_bd PF12755.7 CRK29288.1 - 3.6e-09 37.1 0.1 0.36 11.5 0.0 6.8 4 2 4 8 8 6 2 Vacuolar 14 Fab1-binding region RIX1 PF08167.12 CRK29288.1 - 1.1e-08 35.1 0.0 4.1e-06 26.7 0.0 4.0 3 0 0 3 3 3 1 rRNA processing/ribosome biogenesis MMS19_C PF12460.8 CRK29288.1 - 9.1e-07 28.3 0.4 5.4e-05 22.5 0.0 3.1 3 0 0 3 3 3 1 RNAPII transcription regulator C-terminal CLASP_N PF12348.8 CRK29288.1 - 1e-06 28.5 0.2 0.029 13.9 0.1 5.1 3 1 0 4 4 4 1 CLASP N terminal PAS_4 PF08448.10 CRK29288.1 - 2.4e-06 27.7 0.0 0.096 12.9 0.0 4.2 3 0 0 3 3 3 2 PAS fold Cnd1 PF12717.7 CRK29288.1 - 5.2e-05 23.3 0.1 1.5 8.9 0.0 4.9 3 2 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 PAS_2 PF08446.11 CRK29288.1 - 0.0005 20.7 0.0 0.13 13.0 0.0 3.5 3 0 0 3 3 3 1 PAS fold TFCD_C PF12612.8 CRK29288.1 - 0.0042 16.9 0.1 1.7 8.4 0.0 4.2 4 1 1 5 5 5 1 Tubulin folding cofactor D C terminal RTP1_C1 PF10363.9 CRK29288.1 - 0.005 17.0 1.4 0.076 13.2 0.1 3.7 5 0 0 5 5 4 1 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 CRK29288.1 - 0.009 16.0 6.3 2.8 8.1 0.0 4.4 5 0 0 5 5 3 2 Armadillo/beta-catenin-like repeat Cohesin_HEAT PF12765.7 CRK29288.1 - 0.012 15.9 0.0 3 8.2 0.0 2.8 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion Telomere_reg-2 PF10193.9 CRK29288.1 - 0.057 13.9 2.2 0.4 11.1 0.3 3.0 2 0 0 2 2 2 0 Telomere length regulation protein Dopey_N PF04118.14 CRK29288.1 - 0.068 12.3 1.6 2.5 7.1 0.0 3.3 3 0 0 3 3 3 0 Dopey, N-terminal V-ATPase_H_N PF03224.14 CRK29288.1 - 0.26 10.5 4.3 0.99 8.6 0.1 3.1 2 1 1 3 3 3 0 V-ATPase subunit H CBS PF00571.28 CRK29289.1 - 7e-16 58.4 0.8 0.00044 20.6 0.0 5.2 5 0 0 5 5 5 4 CBS domain Ytp1 PF10355.9 CRK29290.1 - 1e-112 375.9 5.2 2.6e-112 374.5 2.7 2.1 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 CRK29290.1 - 8.2e-31 105.9 3.9 8.2e-31 105.9 3.9 3.2 4 0 0 4 4 4 1 Domain of unknown function (DUF2427) COX2_TM PF02790.15 CRK29290.1 - 0.021 15.0 0.5 0.45 10.7 0.1 2.7 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane domain BLACT_WH PF17778.1 CRK29291.1 - 5.5e-19 67.9 0.1 1.1e-18 66.9 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B PF00753.27 CRK29291.1 - 1.8e-15 57.5 4.9 7.1e-14 52.3 4.5 2.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CRK29291.1 - 1.7e-07 31.0 0.1 3.5e-07 29.9 0.1 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 CRK29291.1 - 0.0011 18.9 0.1 0.0018 18.2 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 CRK29291.1 - 0.074 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain UCH PF00443.29 CRK29292.1 - 1.9e-32 112.8 0.0 3e-32 112.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CRK29292.1 - 6.5e-22 78.5 4.9 8.6e-22 78.1 4.9 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 CRK29292.1 - 2.4e-06 27.8 0.3 2.4e-06 27.8 0.3 2.4 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein Zn-ribbon_8 PF09723.10 CRK29292.1 - 0.02 15.0 2.5 3.6 7.8 0.1 3.4 3 0 0 3 3 3 0 Zinc ribbon domain zf_C2H2_ZHX PF18387.1 CRK29292.1 - 0.041 13.5 0.2 0.041 13.5 0.2 2.3 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain Peptidase_C98 PF15499.6 CRK29292.1 - 0.14 11.6 3.7 2.2 7.7 3.7 2.3 1 1 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase DZR PF12773.7 CRK29292.1 - 7 6.8 14.4 9.1 6.4 0.1 3.3 2 1 0 2 2 2 0 Double zinc ribbon N6-adenineMlase PF10237.9 CRK29293.1 - 9.2e-12 45.1 0.0 1.4e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase FAD-oxidase_C PF02913.19 CRK29293.1 - 0.0055 16.4 0.2 0.0064 16.2 0.2 1.0 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain NmrA PF05368.13 CRK29294.1 - 1.2e-15 57.8 0.0 2e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 CRK29294.1 - 3.5e-15 56.4 0.0 5.2e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 CRK29294.1 - 1.8e-13 50.6 0.1 4.7e-13 49.2 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CRK29294.1 - 1.1e-09 37.8 0.1 2.1e-09 36.8 0.1 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 CRK29294.1 - 6.6e-07 29.0 0.1 1.2e-06 28.1 0.1 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 CRK29294.1 - 1.5e-06 27.6 0.0 0.00018 20.7 0.0 2.2 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 CRK29294.1 - 1.9e-05 24.2 0.0 3e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 CRK29294.1 - 0.0038 16.4 0.2 0.22 10.7 0.2 2.7 1 1 0 1 1 1 1 Male sterility protein adh_short_C2 PF13561.6 CRK29294.1 - 0.011 15.3 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK29294.1 - 0.041 13.8 0.0 0.64 9.9 0.0 2.2 2 0 0 2 2 2 0 KR domain ApbA PF02558.16 CRK29294.1 - 0.043 13.5 0.0 0.29 10.8 0.0 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA DapB_N PF01113.20 CRK29294.1 - 0.055 13.6 0.0 0.098 12.8 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.15 CRK29294.1 - 0.058 12.5 0.0 0.093 11.8 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein PCI PF01399.27 CRK29295.1 - 2e-11 44.3 0.0 4.9e-11 43.1 0.0 1.7 1 0 0 1 1 1 1 PCI domain Rpn9_C PF18261.1 CRK29295.1 - 1.9e-08 33.7 0.3 4.3e-08 32.6 0.3 1.6 1 0 0 1 1 1 1 Rpn9 C-terminal helix Gaa1 PF04114.14 CRK29296.1 - 1.1e-169 565.6 2.7 1.1e-169 565.6 2.7 1.4 2 0 0 2 2 2 1 Gaa1-like, GPI transamidase component tRNA-synt_1 PF00133.22 CRK29298.1 - 1.9e-217 723.3 0.0 2.2e-216 719.8 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CRK29298.1 - 6.9e-34 117.0 0.0 6.9e-34 117.0 0.0 1.8 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 CRK29298.1 - 1.8e-08 33.5 0.3 0.0029 16.4 0.0 3.9 3 1 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 CRK29298.1 - 4.5e-08 32.8 10.2 5.2e-06 26.1 0.0 3.3 3 1 1 4 4 4 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 CRK29298.1 - 0.0065 15.8 0.0 0.2 11.0 0.0 2.6 2 1 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain CRAL_TRIO PF00650.20 CRK29299.1 - 1.5e-42 145.1 0.1 2.7e-42 144.2 0.1 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CRK29299.1 - 7.8e-16 58.0 0.4 2.8e-15 56.2 0.1 2.2 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 CRK29299.1 - 2.3e-08 34.3 0.0 5e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain HIT PF01230.23 CRK29300.1 - 1e-16 61.5 0.0 1.5e-16 60.9 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 CRK29300.1 - 9.2e-09 35.8 0.1 1.5e-08 35.1 0.1 1.4 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 CRK29300.1 - 0.0028 17.5 0.5 0.0045 16.8 0.5 1.5 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Mog1 PF04603.12 CRK29301.1 - 1e-38 132.8 0.0 1.2e-38 132.6 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein SprT-like PF10263.9 CRK29302.1 - 2e-36 124.3 0.1 3.3e-36 123.6 0.1 1.3 1 0 0 1 1 1 1 SprT-like family Zn_ribbon_SprT PF17283.2 CRK29302.1 - 2.8e-12 46.3 3.6 4.7e-12 45.6 3.6 1.4 1 0 0 1 1 1 1 SprT-like zinc ribbon domain CHDNT PF08073.12 CRK29302.1 - 0.0005 20.0 0.2 0.0011 18.9 0.2 1.5 1 0 0 1 1 1 1 CHDNT (NUC034) domain Zn-ribbon_8 PF09723.10 CRK29302.1 - 0.0033 17.5 0.8 0.0065 16.6 0.8 1.5 1 0 0 1 1 1 1 Zinc ribbon domain HMG_box PF00505.19 CRK29302.1 - 0.061 13.7 0.1 0.12 12.7 0.1 1.5 1 0 0 1 1 1 0 HMG (high mobility group) box Peptidase_M90 PF06167.12 CRK29302.1 - 0.063 12.9 0.2 0.13 11.8 0.0 1.6 2 0 0 2 2 2 0 Glucose-regulated metallo-peptidase M90 DUF4379 PF14311.6 CRK29302.1 - 0.96 9.9 3.4 4.4 7.8 3.4 2.1 1 1 0 1 1 1 0 Probable Zinc-ribbon domain Glucan_synthase PF02364.15 CRK29303.1 - 0 1364.9 0.0 0 1364.4 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component Formyl_trans_N PF00551.19 CRK29304.1 - 6.4e-32 110.7 0.0 1e-31 110.1 0.0 1.3 1 1 0 1 1 1 1 Formyl transferase DBC1 PF14443.6 CRK29305.1 - 0.019 14.9 0.4 6.4 6.8 0.0 2.2 2 0 0 2 2 2 0 DBC1 FAD_binding_4 PF01565.23 CRK29307.1 - 2.8e-22 78.9 0.1 6.5e-22 77.8 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain FAD-oxidase_C PF02913.19 CRK29307.1 - 4.2e-13 49.5 0.0 5.8e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain COesterase PF00135.28 CRK29308.1 - 1.8e-73 248.2 0.0 2.2e-73 247.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CRK29308.1 - 1.5e-08 34.7 0.9 2.9e-06 27.3 0.1 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold His_Phos_2 PF00328.22 CRK29309.1 - 0.085 12.2 0.2 0.16 11.3 0.0 1.5 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 2) Noelin-1 PF12308.8 CRK29309.1 - 0.14 12.1 0.3 0.31 11.1 0.3 1.5 1 0 0 1 1 1 0 Neurogenesis glycoprotein DUF2752 PF10825.8 CRK29310.1 - 0.0095 16.0 3.8 1.1 9.4 0.2 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF2752) zf-ISL3 PF14690.6 CRK29310.1 - 0.071 13.8 0.5 6.3 7.5 0.0 2.8 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 STT3 PF02516.14 CRK29311.1 - 1e-84 285.3 12.7 1e-45 156.6 2.0 3.1 3 0 0 3 3 3 3 Oligosaccharyl transferase STT3 subunit Dpy19 PF10034.9 CRK29311.1 - 0.0075 14.5 0.2 0.01 14.1 0.2 1.2 1 0 0 1 1 1 1 Q-cell neuroblast polarisation ATP-synt_E PF05680.12 CRK29313.1 - 5.4e-25 87.6 0.3 6.1e-25 87.4 0.3 1.0 1 0 0 1 1 1 1 ATP synthase E chain Drf_GBD PF06371.13 CRK29313.1 - 0.016 14.7 0.2 0.018 14.6 0.2 1.1 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain WD40 PF00400.32 CRK29314.1 - 6.5e-07 29.9 11.3 0.25 12.3 0.8 5.8 6 1 0 6 6 6 3 WD domain, G-beta repeat MaoC_dehydratas PF01575.19 CRK29315.1 - 9.7e-21 73.6 0.0 1.8e-20 72.8 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain CAP_GLY PF01302.25 CRK29315.1 - 1.8e-18 66.3 0.1 3.5e-18 65.4 0.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.7 CRK29315.1 - 2.7e-10 40.3 1.3 0.026 15.0 0.1 4.6 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CRK29315.1 - 4.8e-08 32.6 7.2 0.0016 18.2 0.6 4.4 4 2 0 4 4 4 3 Leucine rich repeat LRR_9 PF14580.6 CRK29315.1 - 8.9e-07 28.6 0.1 0.00029 20.4 0.0 2.9 3 0 0 3 3 3 2 Leucine-rich repeat MaoC_dehydrat_N PF13452.6 CRK29315.1 - 4.6e-05 23.5 0.0 0.0022 18.1 0.0 2.5 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase LRR_6 PF13516.6 CRK29315.1 - 7.1e-05 22.6 1.2 3.1 8.1 0.0 6.2 7 0 0 7 7 7 1 Leucine Rich repeat HET PF06985.11 CRK29317.1 - 0.052 13.9 4.3 3.3 8.0 0.1 2.3 1 1 1 2 2 2 0 Heterokaryon incompatibility protein (HET) Aminotran_1_2 PF00155.21 CRK29320.1 - 2.1e-17 63.4 0.0 3.9e-17 62.5 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 CRK29320.1 - 0.078 11.8 0.1 2.8 6.6 0.0 2.5 3 0 0 3 3 3 0 Alanine-glyoxylate amino-transferase Glyco_hydro_125 PF06824.11 CRK29322.1 - 2.2e-177 590.1 0.0 2.6e-177 589.9 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) CDC27 PF09507.10 CRK29323.1 - 3.3e-77 260.7 23.4 3.8e-77 260.5 23.4 1.0 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 CDC45 PF02724.14 CRK29323.1 - 0.29 9.4 10.3 0.38 9.0 10.3 1.2 1 0 0 1 1 1 0 CDC45-like protein SAP PF02037.27 CRK29324.1 - 4.4e-05 23.1 0.5 0.00011 21.9 0.0 1.8 2 0 0 2 2 2 1 SAP domain Snf7 PF03357.21 CRK29325.1 - 7.5e-15 54.9 13.1 1.2e-14 54.3 13.1 1.4 1 0 0 1 1 1 1 Snf7 CDC45 PF02724.14 CRK29325.1 - 0.24 9.6 5.7 0.34 9.1 5.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Glyco_hydro_32N PF00251.20 CRK29326.1 - 1.7e-66 224.9 0.9 3e-66 224.1 0.9 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 CRK29326.1 - 3.8e-18 66.0 0.0 7.3e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Sugar_tr PF00083.24 CRK29327.1 - 1.7e-119 399.6 20.6 2e-119 399.5 20.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK29327.1 - 4.1e-22 78.6 55.9 1.8e-20 73.1 30.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Methyltransf_25 PF13649.6 CRK29329.1 - 1.1e-15 58.1 0.1 2.2e-15 57.1 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CRK29329.1 - 3.7e-15 56.3 0.1 6.5e-15 55.6 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK29329.1 - 1.9e-12 47.3 0.0 2.6e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CRK29329.1 - 1e-10 41.7 0.0 1.2e-10 41.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK29329.1 - 3.4e-10 40.5 0.0 5.6e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 CRK29329.1 - 1e-07 31.7 0.2 1.5e-07 31.1 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 CRK29329.1 - 2.8e-06 27.0 0.1 3.6e-06 26.6 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 CRK29329.1 - 4.3e-06 26.2 0.0 5.3e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 CRK29329.1 - 0.00054 19.9 0.1 0.00098 19.0 0.1 1.3 1 1 0 1 1 1 1 Hypothetical methyltransferase N2227 PF07942.12 CRK29329.1 - 0.0056 15.9 0.0 0.012 14.8 0.0 1.5 1 1 1 2 2 2 1 N2227-like protein CMAS PF02353.20 CRK29329.1 - 0.038 13.3 0.0 0.046 13.0 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase GidB PF02527.15 CRK29329.1 - 0.061 12.6 0.1 0.11 11.7 0.1 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_9 PF08003.11 CRK29329.1 - 0.1 11.5 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_16 PF10294.9 CRK29329.1 - 0.12 12.1 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_32 PF13679.6 CRK29329.1 - 0.15 12.0 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 CRK29329.1 - 0.18 10.8 0.0 0.24 10.4 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase GH131_N PF18271.1 CRK29330.1 - 1.1e-64 218.6 0.0 1.3e-64 218.3 0.0 1.1 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain CBM_1 PF00734.18 CRK29330.1 - 8.3e-13 48.1 10.3 2.4e-12 46.6 10.3 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain SPX PF03105.19 CRK29335.1 - 2.4e-14 54.1 9.3 2e-06 28.0 0.2 3.1 1 1 2 3 3 3 3 SPX domain VTC PF09359.10 CRK29335.1 - 4.3e-05 23.1 2.6 4.9e-05 22.9 0.1 1.9 2 0 0 2 2 2 1 VTC domain AbiH PF14253.6 CRK29335.1 - 0.0099 15.8 0.1 0.014 15.2 0.1 1.2 1 0 0 1 1 1 1 Bacteriophage abortive infection AbiH HTH_29 PF13551.6 CRK29335.1 - 0.064 13.3 0.0 4.3 7.4 0.0 2.4 2 0 0 2 2 2 0 Winged helix-turn helix TrmB PF01978.19 CRK29335.1 - 0.13 12.1 0.4 0.72 9.8 0.3 2.0 1 1 1 2 2 2 0 Sugar-specific transcriptional regulator TrmB Ank_2 PF12796.7 CRK29336.1 - 0.17 12.5 0.0 0.94 10.1 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Hexokinase_2 PF03727.16 CRK29337.1 - 3.5e-31 108.5 0.0 4.1e-31 108.2 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 CRK29337.1 - 0.0031 17.4 0.0 0.0042 17.0 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Ribophorin_I PF04597.14 CRK29338.1 - 1.2e-151 505.8 0.0 1.4e-151 505.6 0.0 1.0 1 0 0 1 1 1 1 Ribophorin I CREPT PF16566.5 CRK29338.1 - 0.12 12.6 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour GYF PF02213.16 CRK29338.1 - 0.29 10.8 1.6 82 3.0 0.1 3.7 4 0 0 4 4 4 0 GYF domain Pil1 PF13805.6 CRK29340.1 - 1.8e-109 365.3 3.8 2.2e-109 365.0 3.8 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 HSP20 PF00011.21 CRK29341.1 - 6e-08 32.8 0.0 0.0023 18.0 0.4 2.8 1 1 1 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CRK29341.1 - 0.0021 17.6 0.0 0.019 14.5 0.0 2.3 2 1 0 2 2 2 1 HSP20-like domain found in ArsA Glyco_hydro_71 PF03659.14 CRK29343.1 - 8.5e-129 429.6 1.7 1.1e-128 429.3 1.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 WW PF00397.26 CRK29344.1 - 2.2e-10 40.4 0.1 6.3e-10 39.0 0.1 1.9 1 0 0 1 1 1 1 WW domain PhoD PF09423.10 CRK29344.1 - 2.1e-05 23.7 0.2 0.0025 16.9 0.1 2.3 2 0 0 2 2 2 2 PhoD-like phosphatase DUF3336 PF11815.8 CRK29345.1 - 1.6e-19 70.0 5.2 1.4e-13 50.7 1.2 3.2 3 1 1 4 4 4 2 Domain of unknown function (DUF3336) Patatin PF01734.22 CRK29345.1 - 5.9e-12 46.2 2.4 7e-12 46.0 0.5 2.0 2 0 0 2 2 2 1 Patatin-like phospholipase Leo1 PF04004.13 CRK29346.1 - 3e-31 108.5 0.0 6.3e-31 107.4 0.0 1.5 1 0 0 1 1 1 1 Leo1-like protein CWC25 PF12542.8 CRK29346.1 - 0.032 15.1 0.3 0.032 15.1 0.3 2.6 3 0 0 3 3 3 0 Pre-mRNA splicing factor Arteri_nsp7a PF16749.5 CRK29346.1 - 0.1 12.8 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Arterivirus nonstructural protein 7 alpha Mob1_phocein PF03637.17 CRK29348.1 - 3.3e-44 150.9 0.0 6.6e-44 149.9 0.0 1.5 1 1 0 1 1 1 1 Mob1/phocein family Xan_ur_permease PF00860.20 CRK29349.1 - 6.8e-10 38.2 10.7 7.2e-10 38.1 10.7 1.0 1 0 0 1 1 1 1 Permease family Sulfate_transp PF00916.20 CRK29349.1 - 7.5e-06 24.9 2.5 8.3e-06 24.8 2.5 1.0 1 0 0 1 1 1 1 Sulfate permease family Pkinase PF00069.25 CRK29362.1 - 6.8e-06 25.6 0.4 2.9e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 CRK29362.1 - 1.8e-05 24.8 0.2 9e-05 22.5 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CRK29362.1 - 0.00076 19.1 1.5 0.0079 15.8 0.0 2.4 2 0 0 2 2 2 1 Choline/ethanolamine kinase Kdo PF06293.14 CRK29362.1 - 0.0011 18.4 0.0 0.0022 17.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TMF_DNA_bd PF12329.8 CRK29362.1 - 0.014 15.4 1.7 0.014 15.4 1.7 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding WDCP PF15390.6 CRK29362.1 - 0.26 9.6 2.9 0.46 8.8 2.9 1.5 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Sex_peptide PF08138.11 CRK29362.1 - 0.33 11.1 0.9 0.72 10.1 0.9 1.5 1 0 0 1 1 1 0 Sex peptide (SP) family ADIP PF11559.8 CRK29365.1 - 0.005 16.9 9.3 0.005 16.9 9.3 2.6 1 1 1 2 2 2 1 Afadin- and alpha -actinin-Binding COG5 PF10392.9 CRK29365.1 - 0.016 15.4 2.1 0.036 14.2 2.1 1.6 1 0 0 1 1 1 0 Golgi transport complex subunit 5 TPR_14 PF13428.6 CRK29365.1 - 0.13 13.2 4.5 8.3 7.5 0.9 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat IFT57 PF10498.9 CRK29365.1 - 0.47 9.4 13.9 0.78 8.6 13.9 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 CtIP_N PF10482.9 CRK29365.1 - 2.7 8.1 18.6 1.9 8.5 7.8 2.3 1 1 1 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain Atg14 PF10186.9 CRK29365.1 - 8.1 5.4 16.6 8.1 5.4 15.6 1.4 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CENP-H PF05837.12 CRK29365.1 - 8.7 6.8 24.5 0.053 13.9 9.5 2.6 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Methyltransf_23 PF13489.6 CRK29370.1 - 1.2e-18 67.6 0.0 1.8e-18 67.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK29370.1 - 2.3e-12 47.5 0.0 1.1e-11 45.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK29370.1 - 1.2e-10 41.4 0.0 0.00027 20.8 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 CRK29370.1 - 4.2e-10 40.1 0.0 1e-09 38.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK29370.1 - 1.3e-07 32.3 0.0 1.4e-06 29.0 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CRK29370.1 - 0.00036 19.9 0.0 0.74 9.1 0.0 2.1 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family PrmA PF06325.13 CRK29370.1 - 0.0016 17.9 0.0 0.0026 17.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 CRK29370.1 - 0.0017 17.9 0.0 0.0035 16.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 CRK29370.1 - 0.023 14.0 0.0 0.043 13.1 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain FtsJ PF01728.19 CRK29370.1 - 0.047 13.8 0.0 0.079 13.1 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.9 CRK29370.1 - 0.13 12.0 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase GidB PF02527.15 CRK29370.1 - 0.24 10.7 0.0 0.58 9.4 0.1 1.5 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G BTB PF00651.31 CRK29372.1 - 4e-12 46.4 0.8 6.9e-10 39.1 0.1 2.4 1 1 1 2 2 2 2 BTB/POZ domain DUF4407 PF14362.6 CRK29373.1 - 0.0027 17.1 0.4 0.0031 16.9 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) DUF4763 PF15960.5 CRK29373.1 - 0.0084 15.4 1.2 0.011 15.1 1.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4763) Spidroin_N PF16763.5 CRK29373.1 - 0.011 15.8 0.3 0.014 15.4 0.3 1.1 1 0 0 1 1 1 0 Major ampullate spidroin 1, spider silk protein 1, N-term APG6_N PF17675.1 CRK29373.1 - 0.011 16.2 3.2 0.015 15.8 3.2 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region zf-PHD-like PF15446.6 CRK29373.1 - 0.014 15.0 2.3 0.018 14.7 2.3 1.3 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain DUF4140 PF13600.6 CRK29373.1 - 0.022 15.2 1.6 0.031 14.7 1.6 1.2 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) FTA4 PF13093.6 CRK29373.1 - 0.023 14.6 0.2 0.024 14.5 0.2 1.1 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF702 PF05142.12 CRK29373.1 - 0.027 15.0 0.9 0.031 14.8 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF702) She9_MDM33 PF05546.11 CRK29373.1 - 0.085 12.7 1.1 0.11 12.3 1.1 1.1 1 0 0 1 1 1 0 She9 / Mdm33 family PI3K_P85_iSH2 PF16454.5 CRK29373.1 - 0.096 12.3 3.0 0.12 11.9 3.0 1.1 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain ZapB PF06005.12 CRK29373.1 - 0.12 12.9 7.4 0.14 12.6 6.8 1.3 1 1 0 1 1 1 0 Cell division protein ZapB Atg14 PF10186.9 CRK29373.1 - 0.14 11.2 4.4 0.17 10.9 4.4 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FadA PF09403.10 CRK29373.1 - 0.38 11.3 4.1 0.53 10.8 4.1 1.1 1 0 0 1 1 1 0 Adhesion protein FadA SbcD_C PF12320.8 CRK29373.1 - 0.6 10.4 4.1 0.88 9.9 4.1 1.2 1 0 0 1 1 1 0 Type 5 capsule protein repressor C-terminal domain Vir_act_alpha_C PF10400.9 CRK29373.1 - 0.81 10.4 4.3 2.6 8.8 4.3 1.8 1 1 0 1 1 1 0 Virulence activator alpha C-term Zn_clus PF00172.18 CRK29373.1 - 0.96 9.6 8.7 1.6 9.0 1.9 2.5 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PSI_integrin PF17205.3 CRK29373.1 - 2 8.2 8.9 48 3.8 9.0 2.4 1 1 0 1 1 1 0 Integrin plexin domain DUF16 PF01519.16 CRK29374.1 - 0.01 16.3 0.1 0.018 15.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF16 RPAP3_C PF13877.6 CRK29375.1 - 0.063 13.8 0.0 3.3 8.3 0.0 2.7 2 1 0 2 2 2 0 Potential Monad-binding region of RPAP3 MFS_1 PF07690.16 CRK29378.1 - 7.1e-36 123.9 40.4 7.1e-36 123.9 40.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK29378.1 - 2.8e-07 29.8 8.6 2.8e-07 29.8 8.6 2.8 2 2 1 3 3 3 1 Sugar (and other) transporter BT1 PF03092.16 CRK29378.1 - 0.012 13.9 0.1 0.02 13.1 0.1 1.5 1 0 0 1 1 1 0 BT1 family Polysacc_synt_4 PF04669.13 CRK29379.1 - 4.5e-22 78.5 0.9 1.8e-20 73.3 0.9 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis AChE_tetra PF08674.10 CRK29379.1 - 0.081 12.6 2.0 0.17 11.6 2.0 1.5 1 0 0 1 1 1 0 Acetylcholinesterase tetramerisation domain DUF1943 PF09172.11 CRK29379.1 - 0.082 12.1 0.6 0.11 11.8 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) DUF3506 PF12014.8 CRK29380.1 - 5.9e-58 194.8 0.0 9.6e-58 194.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3506) F-box-like PF12937.7 CRK29380.1 - 0.00021 21.1 0.1 0.00048 20.0 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CRK29380.1 - 0.0084 16.0 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 F-box domain SMN PF06003.12 CRK29380.1 - 0.054 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) MFS_1 PF07690.16 CRK29381.1 - 6.9e-37 127.2 48.1 2.4e-36 125.4 30.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK29381.1 - 1e-13 51.0 1.6 1e-13 51.0 1.6 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 CRK29381.1 - 1.3e-08 34.6 0.2 1.3e-08 34.6 0.2 2.3 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_1 PF07690.16 CRK29382.1 - 9.7e-35 120.1 25.2 2.1e-34 119.0 25.5 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily YfhO PF09586.10 CRK29382.1 - 0.083 11.1 3.1 0.088 11.0 1.4 1.8 2 0 0 2 2 2 0 Bacterial membrane protein YfhO DUF4064 PF13273.6 CRK29382.1 - 0.16 12.2 7.6 5.7 7.3 2.6 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) Phage_holin_2_3 PF16080.5 CRK29382.1 - 0.35 10.7 2.5 26 4.7 0.0 3.2 2 0 0 2 2 2 0 Bacteriophage holin family HP1 MutS_V PF00488.21 CRK29383.1 - 2e-66 223.6 1.3 2.6e-66 223.3 0.3 1.8 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 CRK29383.1 - 7.3e-42 143.8 0.1 2.1e-41 142.3 0.1 1.9 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.17 CRK29383.1 - 4.4e-17 62.6 0.0 1.5e-16 61.0 0.0 1.9 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 CRK29383.1 - 4.9e-14 52.4 0.8 1e-13 51.4 0.8 1.6 1 0 0 1 1 1 1 MutS family domain IV MutS_I PF01624.20 CRK29383.1 - 6.1e-12 45.8 0.3 5.2e-11 42.8 0.3 2.4 1 1 0 1 1 1 1 MutS domain I AAA_23 PF13476.6 CRK29383.1 - 0.0026 18.3 1.8 0.022 15.3 0.2 2.4 2 0 0 2 2 2 1 AAA domain AAA_27 PF13514.6 CRK29383.1 - 0.062 12.9 0.3 0.16 11.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 CRK29383.1 - 0.099 12.4 0.1 0.26 11.0 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 CRK29383.1 - 0.1 12.3 0.2 0.2 11.4 0.2 1.5 1 0 0 1 1 1 0 AAA domain SPT6_acidic PF14632.6 CRK29383.1 - 0.13 12.9 11.4 0.32 11.6 9.5 2.6 1 1 1 2 2 2 0 Acidic N-terminal SPT6 AAA_21 PF13304.6 CRK29383.1 - 0.2 11.4 2.5 0.14 12.0 0.2 2.0 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Dehydratase_hem PF13816.6 CRK29387.1 - 2.8e-111 371.9 0.0 3.2e-111 371.7 0.0 1.0 1 0 0 1 1 1 1 Haem-containing dehydratase DUF4188 PF13826.6 CRK29387.1 - 5.2e-07 30.0 0.0 0.00023 21.5 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4188) ABM PF03992.16 CRK29387.1 - 0.01 15.9 0.0 0.15 12.2 0.0 2.3 2 0 0 2 2 2 0 Antibiotic biosynthesis monooxygenase adh_short PF00106.25 CRK29388.1 - 4.9e-07 29.4 0.0 2.4e-05 23.9 0.0 2.9 2 2 0 2 2 2 1 short chain dehydrogenase CN_hydrolase PF00795.22 CRK29389.1 - 3.3e-43 147.9 0.0 4.1e-43 147.6 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase adh_short PF00106.25 CRK29390.1 - 1.3e-24 86.7 0.1 1.8e-15 56.9 0.0 3.7 3 1 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 CRK29390.1 - 3.4e-11 43.2 0.0 8e-07 28.8 0.0 3.4 3 1 0 3 3 3 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK29390.1 - 2.2e-08 34.2 0.7 0.00072 19.5 0.0 2.9 3 0 0 3 3 3 2 KR domain Epimerase PF01370.21 CRK29390.1 - 4.8e-08 32.8 0.0 0.0005 19.6 0.0 2.5 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family TMP_2 PF06791.13 CRK29390.1 - 0.0013 18.4 0.4 1.6 8.3 0.0 2.2 2 0 0 2 2 2 2 Prophage tail length tape measure protein GIDA PF01134.22 CRK29390.1 - 0.0019 17.3 0.3 1.2 8.1 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A ProQ_C PF17516.2 CRK29390.1 - 0.0054 16.1 1.1 2.9 7.4 0.1 2.4 2 0 0 2 2 2 2 ProQ C-terminal domain Wax2_C PF12076.8 CRK29390.1 - 0.031 14.0 0.0 9.1 6.0 0.0 2.5 2 0 0 2 2 2 0 WAX2 C-terminal domain E1-N PF14463.6 CRK29390.1 - 0.11 12.3 0.4 1.2 9.0 0.0 2.1 2 0 0 2 2 2 0 E1 N-terminal domain RNase_II_C_S1 PF18614.1 CRK29390.1 - 0.14 12.1 2.0 18 5.4 0.2 2.6 2 0 0 2 2 2 0 RNase II-type exonuclease C-terminal S1 domain ApbA PF02558.16 CRK29390.1 - 0.22 11.2 1.4 10 5.8 0.0 3.1 4 0 0 4 4 4 0 Ketopantoate reductase PanE/ApbA GDP_Man_Dehyd PF16363.5 CRK29390.1 - 0.62 9.4 4.2 1.6 8.1 0.0 2.6 3 0 0 3 3 3 0 GDP-mannose 4,6 dehydratase DUF983 PF06170.12 CRK29390.1 - 1.2 9.6 3.1 32 5.0 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF983) G-patch PF01585.23 CRK29391.1 - 1e-06 28.5 0.2 2e-06 27.6 0.2 1.5 1 0 0 1 1 1 1 G-patch domain Sec1 PF00995.23 CRK29392.1 - 8e-52 177.2 0.0 9.4e-52 177.0 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Pyrophosphatase PF00719.19 CRK29399.1 - 8e-43 146.0 0.0 1.1e-42 145.6 0.0 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase Peptidase_S10 PF00450.22 CRK29400.1 - 5.6e-88 296.1 0.0 9.5e-88 295.4 0.0 1.3 1 1 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_3 PF07859.13 CRK29401.1 - 5e-16 59.2 1.0 7.3e-16 58.7 1.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 CRK29401.1 - 8.8e-10 38.0 0.0 1.2e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase RTA1 PF04479.13 CRK29402.1 - 7.2e-57 192.3 8.3 7.2e-57 192.3 8.3 1.5 2 0 0 2 2 2 1 RTA1 like protein UPF0767 PF15990.5 CRK29402.1 - 0.074 13.2 0.4 0.14 12.3 0.4 1.5 1 0 0 1 1 1 0 UPF0767 family DUF4131 PF13567.6 CRK29402.1 - 0.57 9.8 18.1 0.063 12.9 4.2 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) DUF3188 PF11384.8 CRK29402.1 - 0.87 9.3 4.1 7.8 6.3 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3188) Glyco_hydro_18 PF00704.28 CRK29403.1 - 3e-17 63.3 0.0 4.5e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Fungal_trans PF04082.18 CRK29404.1 - 1.9e-23 82.8 1.4 2.7e-23 82.3 1.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pox_A_type_inc PF04508.12 CRK29404.1 - 0.17 11.8 1.4 0.3 11.0 1.4 1.4 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Regulator_TrmB PF11495.8 CRK29404.1 - 0.24 10.5 0.0 0.39 9.9 0.0 1.2 1 0 0 1 1 1 0 Archaeal transcriptional regulator TrmB TrkH PF02386.16 CRK29405.1 - 2.1e-118 395.9 4.6 1.2e-116 390.2 5.6 2.0 2 0 0 2 2 2 2 Cation transport protein Na_H_Exchanger PF00999.21 CRK29406.1 - 5.8e-43 147.1 23.6 7.3e-43 146.8 23.6 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family MAD PF05557.13 CRK29410.1 - 2.8e-59 201.1 62.7 2.6e-58 198.0 62.4 2.0 1 1 0 1 1 1 1 Mitotic checkpoint protein Git3 PF11710.8 CRK29410.1 - 3.9e-58 196.6 19.4 5.9e-58 196.0 19.4 1.2 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 CRK29410.1 - 1.2e-05 24.8 0.4 2.1e-05 24.0 0.4 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_2 PF00002.24 CRK29410.1 - 0.001 18.4 6.8 0.0017 17.7 6.8 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) DUF4834 PF16118.5 CRK29410.1 - 6.8 7.7 0.0 6.8 7.7 0.0 3.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4834) Tam41_Mmp37 PF09139.11 CRK29411.1 - 8.7e-123 409.9 0.0 1.3e-122 409.3 0.0 1.2 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial tRNA_bind PF01588.20 CRK29412.1 - 4.5e-22 78.0 0.1 1e-21 76.8 0.1 1.7 1 1 0 1 1 1 1 Putative tRNA binding domain GST_C_2 PF13410.6 CRK29412.1 - 1.9e-05 24.6 0.0 3.7e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CRK29412.1 - 0.00019 21.6 0.8 0.0018 18.5 0.0 2.5 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CRK29412.1 - 0.03 14.5 0.0 0.085 13.1 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain SNF2_N PF00176.23 CRK29413.1 - 1.5e-62 211.3 0.0 3.1e-62 210.3 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CRK29413.1 - 1.6e-22 79.9 0.0 4.1e-22 78.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CRK29413.1 - 2.9e-06 27.4 0.0 1.1e-05 25.5 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CRK29413.1 - 8.7e-06 25.1 0.0 8.7e-06 25.1 0.0 1.6 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase HDA2-3 PF11496.8 CRK29413.1 - 0.0085 15.3 0.0 0.0085 15.3 0.0 2.7 3 1 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 Glyco_hydro_16 PF00722.21 CRK29414.1 - 2.4e-13 49.9 0.0 3.5e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 CRK29414.1 - 2.3e-06 26.3 1.1 0.013 14.0 0.0 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Sld5 PF05916.11 CRK29415.1 - 4e-30 104.5 0.0 6.8e-30 103.7 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein MIP PF00230.20 CRK29416.1 - 2.2e-43 148.6 15.5 2.8e-43 148.3 15.5 1.0 1 0 0 1 1 1 1 Major intrinsic protein Vut_1 PF02592.15 CRK29416.1 - 1.3 9.3 11.0 0.3 11.4 3.0 3.1 2 1 1 3 3 3 0 Putative vitamin uptake transporter NPP1 PF05630.11 CRK29417.1 - 0.0096 16.1 1.8 0.013 15.7 1.8 1.4 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) DUF5519 PF17648.1 CRK29418.1 - 0.00012 22.0 0.6 0.00021 21.2 0.6 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5519) Abhydrolase_9_N PF15420.6 CRK29419.1 - 0.026 14.5 1.7 0.56 10.2 0.1 2.3 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus DUF805 PF05656.14 CRK29419.1 - 0.033 14.6 0.2 0.1 13.0 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF805) Aminotran_3 PF00202.21 CRK29420.1 - 6e-06 25.2 0.0 7.6e-06 24.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III adh_short PF00106.25 CRK29421.1 - 5.3e-23 81.5 0.1 2.7e-21 75.9 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CRK29421.1 - 1.5e-15 57.5 0.2 1.7e-13 50.7 0.1 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK29421.1 - 6.4e-08 32.7 0.0 9e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 KR domain CRCB PF02537.15 CRK29421.1 - 0.12 12.7 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 CrcB-like protein, Camphor Resistance (CrcB) SUZ PF12752.7 CRK29423.1 - 0.00056 20.6 7.2 0.00056 20.6 7.2 4.7 4 2 0 4 4 4 1 SUZ domain SUIM_assoc PF16619.5 CRK29423.1 - 0.0066 16.5 3.1 0.012 15.7 0.1 2.7 2 1 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 Fe_hyd_lg_C PF02906.14 CRK29424.1 - 2.3e-44 151.9 0.0 9.9e-43 146.5 0.0 2.6 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain zf-H2C2_2 PF13465.6 CRK29427.1 - 2.7e-06 27.5 10.2 3.8e-06 27.1 1.1 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 CRK29427.1 - 2.9e-05 24.3 0.3 2.9e-05 24.3 0.3 3.7 3 1 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 CRK29427.1 - 3.2e-05 23.8 0.5 0.07 13.1 0.0 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger Trypan_PARP PF05887.11 CRK29427.1 - 7e-05 22.8 13.3 0.00015 21.8 13.3 1.5 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) FOXP-CC PF16159.5 CRK29427.1 - 0.00027 21.5 11.4 0.17 12.5 0.0 3.7 3 1 1 4 4 4 2 FOXP coiled-coil domain SPX PF03105.19 CRK29427.1 - 0.0011 19.0 6.8 0.0017 18.4 6.8 1.2 1 0 0 1 1 1 1 SPX domain zf-C2H2_4 PF13894.6 CRK29427.1 - 0.0088 16.8 8.7 0.014 16.2 0.3 3.2 3 0 0 3 3 3 1 C2H2-type zinc finger DUF5595 PF18077.1 CRK29427.1 - 0.06 13.4 0.3 0.16 12.1 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5595) ADH_zinc_N_2 PF13602.6 CRK29428.1 - 3.5e-12 47.5 0.0 1.2e-11 45.8 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase LRR_4 PF12799.7 CRK29428.1 - 3.2e-08 33.7 4.3 0.48 10.9 1.9 4.9 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CRK29428.1 - 9.4e-07 28.4 4.1 0.12 12.5 0.0 5.6 6 0 0 6 6 6 2 Leucine Rich repeat LRR_8 PF13855.6 CRK29428.1 - 8.3e-05 22.3 6.5 2.5 7.9 0.0 4.9 4 1 0 4 4 4 3 Leucine rich repeat LRR_1 PF00560.33 CRK29428.1 - 0.00015 21.8 0.1 27 5.8 0.1 5.7 5 0 0 5 5 5 1 Leucine Rich Repeat ADH_zinc_N PF00107.26 CRK29428.1 - 0.075 13.0 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 Zinc-binding dehydrogenase SDA1 PF05285.12 CRK29430.1 - 0.019 14.4 29.1 0.025 14.0 29.1 1.1 1 0 0 1 1 1 0 SDA1 Presenilin PF01080.17 CRK29430.1 - 0.51 9.0 3.3 0.8 8.4 3.3 1.3 1 0 0 1 1 1 0 Presenilin Nop14 PF04147.12 CRK29430.1 - 1.4 7.1 29.4 1.9 6.6 29.4 1.0 1 0 0 1 1 1 0 Nop14-like family SWI-SNF_Ssr4 PF08549.10 CRK29432.1 - 2.5e-276 919.0 0.4 3.2e-276 918.6 0.4 1.1 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1750) 6PGD PF00393.19 CRK29432.1 - 1e-160 533.8 0.0 1.9e-126 421.3 0.0 2.4 2 0 0 2 2 2 2 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 CRK29432.1 - 6.7e-67 224.6 0.0 2.1e-48 164.4 0.0 2.5 2 0 0 2 2 2 2 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 CRK29432.1 - 0.00016 21.9 0.0 1.5 9.1 0.0 3.2 2 0 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Phage_GP20 PF06810.11 CRK29432.1 - 1.1 9.1 4.7 1.8 8.4 4.0 1.7 1 1 0 1 1 1 0 Phage minor structural protein GP20 WSC PF01822.19 CRK29456.1 - 1.5e-82 271.8 80.6 4.8e-19 68.3 9.3 5.3 5 0 0 5 5 5 5 WSC domain Glyoxal_oxid_N PF07250.11 CRK29456.1 - 1.6e-24 86.5 0.0 2.7e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 CRK29456.1 - 5.4e-20 71.5 0.0 1.2e-19 70.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) R3H PF01424.22 CRK29458.1 - 1.2e-16 60.5 0.1 2e-16 59.7 0.1 1.4 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.17 CRK29458.1 - 9.7e-07 28.7 55.4 0.00017 21.6 13.6 11.7 11 1 0 11 11 11 7 NF-X1 type zinc finger APH PF01636.23 CRK29461.1 - 5.8e-10 39.5 0.1 8.7e-10 38.9 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CRK29461.1 - 0.19 11.3 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase FTR1 PF03239.14 CRK29465.1 - 1.3e-78 264.3 7.6 1.6e-78 264.0 7.6 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family Cu-oxidase PF00394.22 CRK29467.1 - 1.5e-39 135.7 0.3 1.4e-35 122.8 0.1 2.1 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 CRK29467.1 - 1.5e-38 131.5 0.7 2.3e-38 130.8 0.7 1.3 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 CRK29467.1 - 0.00025 20.8 1.1 0.023 14.4 0.4 2.9 2 1 0 2 2 2 1 Multicopper oxidase UCH_1 PF13423.6 CRK29490.1 - 8.3e-93 311.5 0.0 1.6e-92 310.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase F_bP_aldolase PF01116.20 CRK29490.1 - 1.7e-89 300.0 0.0 2.3e-89 299.6 0.0 1.2 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II RNase_T PF00929.24 CRK29490.1 - 3.5e-19 70.0 0.0 6.3e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 Exonuclease Mito_carr PF00153.27 CRK29493.1 - 1.6e-53 178.6 4.2 3.1e-18 65.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CRK29493.1 - 0.82 8.8 5.1 6.7 5.8 4.6 2.7 1 1 0 1 1 1 0 Gammaproteobacterial serine protease Trypan_PARP PF05887.11 CRK29495.1 - 5.9e-05 23.1 7.6 0.061 13.3 0.4 2.6 2 0 0 2 2 2 2 Procyclic acidic repetitive protein (PARP) Tudor_3 PF18115.1 CRK29497.1 - 2e-06 27.6 0.1 3.2e-06 26.9 0.1 1.4 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain DUF4537 PF15057.6 CRK29497.1 - 6.4e-05 23.0 0.0 0.00011 22.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) LBR_tudor PF09465.10 CRK29497.1 - 0.023 14.5 0.1 0.058 13.2 0.0 1.7 2 0 0 2 2 2 0 Lamin-B receptor of TUDOR domain FlxA PF14282.6 CRK29497.1 - 0.029 14.4 0.6 0.029 14.4 0.6 2.0 2 0 0 2 2 2 0 FlxA-like protein DUF1325 PF07039.11 CRK29497.1 - 0.075 13.1 2.0 0.082 13.0 0.5 1.8 2 0 0 2 2 2 0 SGF29 tudor-like domain IL11 PF07400.11 CRK29497.1 - 0.13 11.9 0.1 0.2 11.3 0.1 1.3 1 0 0 1 1 1 0 Interleukin 11 ParA PF10609.9 CRK29499.1 - 6.8e-95 317.2 0.1 7.8e-95 317.0 0.1 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 CRK29499.1 - 1.5e-11 44.5 0.0 3.4e-11 43.3 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 CRK29499.1 - 8.2e-10 38.9 0.1 3.2e-08 33.7 0.1 2.1 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 CRK29499.1 - 5.5e-06 25.9 0.1 8.3e-06 25.3 0.1 1.4 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 CRK29499.1 - 1.5e-05 24.3 0.6 0.00093 18.5 0.1 2.8 2 1 1 3 3 3 1 Anion-transporting ATPase Fer4_NifH PF00142.18 CRK29499.1 - 0.00058 19.4 0.0 0.044 13.2 0.0 2.3 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CBP_BcsQ PF06564.12 CRK29499.1 - 0.00077 19.0 0.6 0.0078 15.7 0.1 2.0 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ AAA_25 PF13481.6 CRK29499.1 - 0.0034 17.0 0.0 0.0093 15.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_26 PF13500.6 CRK29499.1 - 0.0085 15.9 0.5 2.9 7.7 0.0 2.2 2 0 0 2 2 2 2 AAA domain MeaB PF03308.16 CRK29499.1 - 0.021 13.8 0.2 0.035 13.1 0.2 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CLP1_P PF16575.5 CRK29499.1 - 0.029 14.1 0.0 0.064 13.1 0.0 1.5 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop FTHFS PF01268.19 CRK29499.1 - 0.12 10.5 0.0 0.17 10.1 0.0 1.2 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase adh_short_C2 PF13561.6 CRK29500.1 - 2.2e-34 119.0 2.9 4.3e-33 114.8 2.9 2.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRK29500.1 - 3.5e-27 95.1 0.2 3.5e-27 95.1 0.2 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 CRK29500.1 - 1.5e-06 28.2 0.3 2.6e-06 27.5 0.3 1.3 1 0 0 1 1 1 1 KR domain TMF_TATA_bd PF12325.8 CRK29502.1 - 0.0016 18.6 1.6 0.0031 17.7 1.6 1.4 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding TSC22 PF01166.18 CRK29502.1 - 0.0023 18.2 7.6 0.12 12.7 1.0 2.8 2 1 1 3 3 2 2 TSC-22/dip/bun family CENP-F_leu_zip PF10473.9 CRK29502.1 - 0.0085 16.1 2.3 0.016 15.2 2.3 1.4 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.8 CRK29502.1 - 0.011 15.8 3.7 0.022 14.8 3.7 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding TMF_DNA_bd PF12329.8 CRK29502.1 - 0.017 15.1 3.3 0.031 14.3 3.3 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding BRE1 PF08647.11 CRK29502.1 - 0.022 14.8 0.2 0.04 14.0 0.2 1.3 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase DUF3450 PF11932.8 CRK29502.1 - 0.025 13.9 2.0 0.041 13.2 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) APG6_N PF17675.1 CRK29502.1 - 0.03 14.8 4.5 0.057 13.9 4.5 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region HMMR_N PF15905.5 CRK29502.1 - 0.035 13.6 0.7 0.057 12.9 0.7 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal MAD PF05557.13 CRK29502.1 - 0.038 12.4 3.0 0.057 11.8 3.0 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein YabA PF06156.13 CRK29502.1 - 0.051 14.2 4.6 0.39 11.4 4.6 2.3 1 1 0 1 1 1 0 Initiation control protein YabA T3SS_needle_E PF08988.10 CRK29502.1 - 0.051 13.7 0.6 0.13 12.4 0.6 1.7 1 0 0 1 1 1 0 Type III secretion system, cytoplasmic E component of needle Spc7 PF08317.11 CRK29502.1 - 0.067 12.1 2.1 0.099 11.5 2.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein GIT_CC PF16559.5 CRK29502.1 - 0.089 12.7 7.8 0.54 10.2 6.2 2.7 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor bZIP_1 PF00170.21 CRK29502.1 - 0.093 12.8 4.0 0.62 10.2 0.5 2.4 1 1 1 2 2 2 0 bZIP transcription factor CLZ PF16526.5 CRK29502.1 - 0.14 12.6 3.0 0.36 11.2 3.0 1.7 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DivIC PF04977.15 CRK29502.1 - 0.25 11.1 6.7 0.95 9.3 1.3 2.4 1 1 1 2 2 2 0 Septum formation initiator ZapB PF06005.12 CRK29502.1 - 0.57 10.7 9.3 8.8 6.9 9.3 2.4 1 1 0 1 1 1 0 Cell division protein ZapB FlxA PF14282.6 CRK29502.1 - 0.95 9.5 4.5 2 8.4 4.1 1.7 1 1 0 1 1 1 0 FlxA-like protein Cwf_Cwc_15 PF04889.12 CRK29502.1 - 2.2 7.9 10.0 4.7 6.9 10.0 1.6 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NRBF2 PF08961.10 CRK29502.1 - 2.7 7.5 8.5 3 7.4 1.4 2.4 1 1 1 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator FUSC PF04632.12 CRK29502.1 - 3.8 5.9 4.6 1.4 7.3 1.9 1.6 2 0 0 2 2 2 0 Fusaric acid resistance protein family PRKG1_interact PF15898.5 CRK29502.1 - 4 8.4 6.5 5.7 7.9 0.2 2.6 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain DNA_pol_phi PF04931.13 CRK29502.1 - 7.6 4.5 10.9 11 4.0 10.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi PRA1 PF03208.19 CRK29504.1 - 0.00022 20.8 0.7 0.00022 20.8 0.7 2.5 3 0 0 3 3 3 1 PRA1 family protein VHS PF00790.19 CRK29506.1 - 2.5e-16 59.8 0.5 8.1e-14 51.7 0.0 2.6 1 1 1 2 2 2 2 VHS domain SH3_1 PF00018.28 CRK29506.1 - 8e-16 57.4 0.1 1.4e-15 56.6 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 CRK29506.1 - 7.5e-15 54.4 0.0 1.5e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 CRK29506.1 - 3.4e-14 52.4 0.1 7.5e-14 51.3 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.14 CRK29506.1 - 1.1e-10 41.7 2.7 1.5e-10 41.2 1.8 1.7 2 0 0 2 2 2 1 GAT domain UIM PF02809.20 CRK29506.1 - 0.018 14.9 5.8 0.038 13.9 5.8 1.6 1 0 0 1 1 1 0 Ubiquitin interaction motif ATG13 PF10033.9 CRK29509.1 - 4.6e-76 255.7 0.0 6.6e-76 255.2 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 13 RCC1 PF00415.18 CRK29511.1 - 8.1e-36 122.4 2.3 7.9e-07 29.6 0.2 8.2 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat Ank_4 PF13637.6 CRK29511.1 - 2.6e-17 62.9 6.4 2.4e-07 31.2 0.4 4.1 2 2 2 4 4 4 2 Ankyrin repeats (many copies) RCC1_2 PF13540.6 CRK29511.1 - 3.7e-16 58.4 11.4 1.3e-06 28.0 0.6 5.5 4 0 0 4 4 4 2 Regulator of chromosome condensation (RCC1) repeat Ank_2 PF12796.7 CRK29511.1 - 2.2e-13 50.6 1.4 2.7e-05 24.6 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CRK29511.1 - 1.2e-12 46.8 4.8 0.31 11.7 0.1 5.0 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 CRK29511.1 - 1.5e-06 28.4 1.3 0.28 11.5 0.1 4.2 4 0 0 4 4 4 2 Ankyrin repeats (many copies) BTB PF00651.31 CRK29511.1 - 2e-06 28.0 0.1 9.4e-06 25.8 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain PRAS PF15798.5 CRK29511.1 - 0.014 16.0 0.7 8.2 7.0 0.0 3.4 3 0 0 3 3 3 0 Proline-rich AKT1 substrate 1 Nucleopor_Nup85 PF07575.13 CRK29511.1 - 0.11 11.1 0.0 12 4.4 0.0 2.1 2 0 0 2 2 2 0 Nup85 Nucleoporin Ank PF00023.30 CRK29511.1 - 0.24 11.9 8.4 11 6.7 0.0 4.4 4 0 0 4 4 4 0 Ankyrin repeat Mito_carr PF00153.27 CRK29513.1 - 1.5e-89 294.1 1.9 9.3e-24 83.2 0.0 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein BofC_C PF08955.10 CRK29513.1 - 0.046 13.8 0.0 22 5.2 0.0 3.2 3 0 0 3 3 3 0 BofC C-terminal domain Serine_protease PF18405.1 CRK29513.1 - 0.2 10.8 2.2 25 3.9 0.0 3.9 3 1 1 5 5 5 0 Gammaproteobacterial serine protease Antimicrobial_8 PF08103.11 CRK29513.1 - 0.33 11.2 2.3 84 3.6 0.1 3.8 3 0 0 3 3 3 0 Uperin family Ran-binding PF05508.11 CRK29515.1 - 1.7e-110 368.9 0.0 2.5e-110 368.4 0.0 1.3 1 0 0 1 1 1 1 RanGTP-binding protein GTP_EFTU PF00009.27 CRK29517.1 - 4.1e-70 235.3 4.2 6.7e-38 130.2 0.4 2.2 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CRK29517.1 - 2.6e-15 56.7 0.1 5.4e-15 55.7 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 CRK29517.1 - 3.2e-08 33.7 0.2 0.028 14.5 0.0 3.9 2 2 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 CRK29517.1 - 0.0018 17.8 1.5 4 7.0 0.0 3.7 5 0 0 5 5 5 2 Ferrous iron transport protein B G-alpha PF00503.20 CRK29517.1 - 0.0026 17.0 0.0 2.2 7.3 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit AAA_29 PF13555.6 CRK29517.1 - 0.0028 17.4 0.4 1.6 8.5 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain PduV-EutP PF10662.9 CRK29517.1 - 0.011 15.5 0.0 17 5.2 0.0 3.6 4 0 0 4 4 4 0 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 CRK29517.1 - 0.015 15.2 0.1 14 5.5 0.1 3.3 2 1 1 3 3 3 0 RsgA GTPase DNA_ligase_OB_2 PF14743.6 CRK29517.1 - 0.09 12.8 0.0 28 4.8 0.0 2.7 2 0 0 2 2 2 0 DNA ligase OB-like domain PDDEXK_10 PF07788.11 CRK29517.1 - 0.11 12.4 0.0 29 4.7 0.0 2.7 2 0 0 2 2 2 0 PD-(D/E)XK nuclease superfamily AIG1 PF04548.16 CRK29517.1 - 0.12 11.7 0.2 17 4.7 0.0 2.4 2 0 0 2 2 2 0 AIG1 family LPD34 PF18852.1 CRK29517.1 - 0.18 11.4 0.0 24 4.4 0.0 2.2 2 0 0 2 2 2 0 Large polyvalent protein associated domain 34 PEPCK_ATP PF01293.20 CRK29519.1 - 2e-134 448.8 0.0 4.8e-96 322.2 0.0 3.1 2 1 1 3 3 3 3 Phosphoenolpyruvate carboxykinase p450 PF00067.22 CRK29521.1 - 9.8e-60 202.6 0.0 1.2e-59 202.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3262 PF11660.8 CRK29521.1 - 0.81 10.1 7.2 1.5 9.2 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3262) Cupin_8 PF13621.6 CRK29523.1 - 1e-14 54.9 0.0 1.6e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain CK_II_beta PF01214.18 CRK29524.1 - 3.6e-74 248.5 0.0 7.5e-74 247.5 0.0 1.5 1 1 0 1 1 1 1 Casein kinase II regulatory subunit PTPRCAP PF15713.5 CRK29524.1 - 0.041 14.2 14.2 0.2 11.9 0.6 2.1 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated SGT1 PF07093.11 CRK29524.1 - 0.065 11.7 2.7 0.097 11.1 2.7 1.2 1 0 0 1 1 1 0 SGT1 protein NUP50 PF08911.11 CRK29524.1 - 1.7 9.3 5.3 0.24 12.1 0.9 1.8 2 0 0 2 2 2 0 NUP50 (Nucleoporin 50 kDa) PBP1_TM PF14812.6 CRK29524.1 - 4.3 7.8 15.7 2.9 8.3 7.0 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RRN3 PF05327.11 CRK29524.1 - 7.9 4.9 12.4 0.057 12.0 4.2 1.5 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 FAM176 PF14851.6 CRK29524.1 - 8 6.1 11.3 1.4 8.6 4.6 2.1 2 0 0 2 2 2 0 FAM176 family DOPA_dioxygen PF08883.11 CRK29526.1 - 3.6e-42 142.9 0.1 4.4e-42 142.6 0.1 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family DUF1993 PF09351.10 CRK29528.1 - 1.8e-52 177.7 0.3 2e-52 177.5 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) Syntaxin_2 PF14523.6 CRK29528.1 - 0.012 16.0 1.0 0.054 13.9 0.3 1.9 1 1 1 2 2 2 0 Syntaxin-like protein p450 PF00067.22 CRK29530.1 - 1.5e-27 96.5 0.0 2.2e-27 95.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pox_Ag35 PF03286.14 CRK29530.1 - 0.52 10.1 7.2 0.82 9.4 6.9 1.5 1 1 0 1 1 1 0 Pox virus Ag35 surface protein UBA2_C PF16195.5 CRK29530.1 - 0.86 10.3 7.6 3.1 8.5 7.6 1.9 1 1 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus ORC6 PF05460.13 CRK29530.1 - 1.5 8.1 5.9 2 7.6 5.9 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) MRI PF15325.6 CRK29530.1 - 9.7 7.3 11.3 5.8 8.1 4.7 2.3 1 1 1 2 2 2 0 Modulator of retrovirus infection Cupin_8 PF13621.6 CRK29532.1 - 5.6e-24 85.2 0.0 9.5e-24 84.5 0.0 1.4 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 CRK29532.1 - 0.0087 16.5 0.0 0.1 13.0 0.0 2.4 2 1 0 2 2 2 1 JmjC domain, hydroxylase Cupin_4 PF08007.12 CRK29532.1 - 0.013 15.0 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 Cupin superfamily protein Rad4 PF03835.15 CRK29534.1 - 2.7e-31 108.3 0.2 5.5e-31 107.2 0.2 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 CRK29534.1 - 1.2e-25 89.7 0.0 2.4e-25 88.7 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 CRK29534.1 - 1.4e-21 76.1 0.0 3.2e-21 74.9 0.0 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 CRK29534.1 - 9e-17 61.8 0.4 9e-17 61.8 0.4 3.4 4 0 0 4 4 4 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 CRK29534.1 - 0.00019 21.9 2.2 0.0017 18.8 0.3 2.9 2 1 0 2 2 2 1 Transglutaminase-like superfamily Zn_clus PF00172.18 CRK29539.1 - 3.4e-09 36.7 13.4 5.5e-09 36.0 13.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 CRK29539.1 - 0.051 12.6 0.1 0.1 11.6 0.1 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain EthD PF07110.11 CRK29541.1 - 7.3e-24 84.8 0.5 1.1e-23 84.2 0.5 1.3 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 CRK29541.1 - 0.00065 20.1 0.0 0.00099 19.6 0.0 1.3 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase DUF2621 PF11084.8 CRK29543.1 - 0.37 10.8 1.1 0.56 10.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2621) Lactonase PF10282.9 CRK29545.1 - 9.7e-71 238.8 0.0 6.3e-70 236.1 0.0 1.8 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller MFS_1 PF07690.16 CRK29547.1 - 1.7e-18 66.7 39.0 1.8e-17 63.3 39.0 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 CRK29547.1 - 2.7e-07 29.4 21.9 4.3e-07 28.8 21.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Plasmid_stab_B PF10784.9 CRK29547.1 - 0.032 14.0 0.0 0.086 12.7 0.0 1.7 1 0 0 1 1 1 0 Plasmid stability protein DUF4231 PF14015.6 CRK29547.1 - 0.053 14.0 1.0 0.23 11.9 0.4 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) Abhydrolase_6 PF12697.7 CRK29549.1 - 0.0072 16.9 0.0 0.014 16.0 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 CRK29549.1 - 0.0081 15.9 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein LIDHydrolase PF10230.9 CRK29549.1 - 0.013 15.0 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase DUF676 PF05057.14 CRK29549.1 - 0.057 12.9 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 CRK29549.1 - 0.084 12.1 0.0 0.26 10.5 0.0 1.8 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Asp PF00026.23 CRK29551.1 - 2.8e-29 102.6 0.0 1.2e-28 100.5 0.0 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease HsbA PF12296.8 CRK29551.1 - 1.3e-15 57.9 0.1 2.5e-15 56.9 0.1 1.5 1 0 0 1 1 1 1 Hydrophobic surface binding protein A TAXi_N PF14543.6 CRK29551.1 - 1.9e-05 25.0 0.3 0.003 17.8 0.3 2.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 CRK29551.1 - 0.053 13.3 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Lactonase PF10282.9 CRK29554.1 - 3.5e-82 276.4 0.0 4.1e-82 276.2 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Zn_clus PF00172.18 CRK29556.1 - 1e-09 38.4 7.9 1.7e-09 37.7 7.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3669 PF12417.8 CRK29558.1 - 1.1e-16 60.8 0.1 2.4e-16 59.7 0.1 1.6 1 0 0 1 1 1 1 Zinc finger protein Zn_clus PF00172.18 CRK29560.1 - 7.3e-09 35.6 7.9 7.3e-09 35.6 7.9 2.2 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1572 PF07609.11 CRK29560.1 - 0.0069 16.2 0.4 4.6 7.0 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1572) OS-D PF03392.13 CRK29560.1 - 0.015 15.4 0.0 11 6.2 0.0 2.6 2 0 0 2 2 2 0 Insect pheromone-binding family, A10/OS-D Arb2 PF09757.9 CRK29560.1 - 0.1 11.7 0.1 38 3.3 0.0 3.4 4 0 0 4 4 4 0 Arb2 domain DUF676 PF05057.14 CRK29562.1 - 8.4e-12 45.1 0.0 6e-05 22.7 0.0 3.1 2 1 1 3 3 3 2 Putative serine esterase (DUF676) IBR PF01485.21 CRK29562.1 - 2e-09 37.5 46.2 1.5e-05 25.1 14.5 3.4 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 CRK29562.1 - 0.0034 17.2 3.5 0.0034 17.2 3.5 3.6 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CRK29562.1 - 0.0097 16.2 5.9 0.0097 16.2 5.9 3.7 3 0 0 3 3 3 1 Ring finger domain Dicty_CAD PF05720.12 CRK29562.1 - 0.13 12.3 0.3 0.35 10.9 0.3 1.7 1 0 0 1 1 1 0 Cell-cell adhesion domain zf-RING_UBOX PF13445.6 CRK29562.1 - 0.19 11.8 8.3 0.029 14.4 3.8 2.0 2 0 0 2 2 2 0 RING-type zinc-finger RRM_1 PF00076.22 CRK29565.1 - 6.2e-17 61.2 0.1 1e-16 60.5 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) eIF3g PF12353.8 CRK29565.1 - 1.2e-07 32.2 4.4 2.2e-07 31.3 4.4 1.6 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_occluded PF16842.5 CRK29565.1 - 0.018 14.9 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif Pox_A_type_inc PF04508.12 CRK29567.1 - 7.4e-05 22.4 0.5 0.0002 21.0 0.5 1.7 1 0 0 1 1 1 1 Viral A-type inclusion protein repeat SlyX PF04102.12 CRK29567.1 - 0.051 14.2 5.8 5.8 7.6 0.1 2.8 2 0 0 2 2 2 0 SlyX GreA_GreB_N PF03449.15 CRK29567.1 - 1.7 8.8 6.3 0.19 11.9 0.3 2.1 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal DAO PF01266.24 CRK29569.1 - 1.3e-76 258.4 24.2 1.6e-31 110.2 1.0 3.0 1 1 2 3 3 3 3 FAD dependent oxidoreductase Mqo PF06039.15 CRK29569.1 - 3.7e-09 35.7 1.5 0.0069 15.0 0.1 3.4 3 0 0 3 3 3 3 Malate:quinone oxidoreductase (Mqo) NAD_binding_8 PF13450.6 CRK29569.1 - 9.8e-05 22.5 1.6 0.00027 21.1 0.2 2.5 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain UPF0180 PF03698.13 CRK29569.1 - 0.0025 17.9 1.0 1.2 9.3 0.1 2.6 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0180) Glyco_hydro_42M PF08532.10 CRK29569.1 - 0.013 15.0 0.0 7.8 5.9 0.0 2.8 3 0 0 3 3 3 0 Beta-galactosidase trimerisation domain K_oxygenase PF13434.6 CRK29569.1 - 0.017 14.3 0.6 3.2 6.8 0.1 2.6 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) CsgF PF10614.9 CRK29569.1 - 0.22 11.8 0.2 37 4.5 0.1 2.7 2 0 0 2 2 2 0 Type VIII secretion system (T8SS), CsgF protein DUF2914 PF11141.8 CRK29569.1 - 0.34 10.7 1.5 69 3.3 0.1 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2914) NAD_binding_9 PF13454.6 CRK29569.1 - 0.54 10.2 6.8 0.68 9.9 0.0 3.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding Adenine_deam_C PF13382.6 CRK29569.1 - 1.2 8.5 5.9 19 4.6 0.2 3.6 3 0 0 3 3 3 0 Adenine deaminase C-terminal domain DUF2415 PF10313.9 CRK29571.1 - 3.7e-26 90.8 0.0 1.8e-11 43.8 0.0 3.0 2 0 0 2 2 2 2 Uncharacterised protein domain (DUF2415) ANAPC4_WD40 PF12894.7 CRK29571.1 - 3.8e-08 33.5 0.0 1.6 9.1 0.0 5.4 4 2 1 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CRK29571.1 - 0.00022 22.0 2.1 3.4 8.7 0.0 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat Auts2 PF15336.6 CRK29571.1 - 0.0099 16.0 7.2 0.0099 16.0 7.2 3.2 2 1 1 3 3 3 1 Autism susceptibility gene 2 protein Cation_efflux PF01545.21 CRK29571.1 - 0.1 12.3 0.0 19 4.9 0.0 2.1 2 0 0 2 2 2 0 Cation efflux family lci PF12197.8 CRK29571.1 - 0.27 11.1 1.1 28 4.6 0.1 2.4 2 0 0 2 2 2 0 Bacillus cereus group antimicrobial protein Rrn6 PF10214.9 CRK29571.1 - 7.3 5.0 0.0 7.3 5.0 0.0 3.5 2 1 2 4 4 4 0 RNA polymerase I-specific transcription-initiation factor HSP70 PF00012.20 CRK29574.1 - 4e-96 322.6 3.5 4.9e-96 322.3 3.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CRK29574.1 - 4.4e-07 29.0 1.0 0.00043 19.2 0.1 2.1 2 0 0 2 2 2 2 MreB/Mbl protein Ploopntkinase3 PF18751.1 CRK29574.1 - 0.0081 16.1 0.3 0.83 9.5 0.0 2.3 1 1 1 2 2 2 2 P-loop Nucleotide Kinase3 DAO PF01266.24 CRK29576.1 - 4.3e-28 98.9 1.5 4.8e-16 59.3 0.1 2.0 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CRK29576.1 - 2.8e-05 24.2 0.3 7.7e-05 22.8 0.1 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CRK29576.1 - 0.033 13.4 0.0 0.096 11.9 0.0 1.7 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.6 CRK29576.1 - 0.096 12.7 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 FAD-NAD(P)-binding ANAPC4_WD40 PF12894.7 CRK29578.1 - 9e-05 22.7 0.0 0.94 9.8 0.0 3.3 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain PRP38_assoc PF12871.7 CRK29578.1 - 0.026 15.1 40.2 0.026 15.1 40.2 3.1 3 0 0 3 3 3 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term WD40 PF00400.32 CRK29578.1 - 0.07 14.0 0.1 2.3 9.2 0.0 3.3 3 0 0 3 3 3 0 WD domain, G-beta repeat Rrn6 PF10214.9 CRK29578.1 - 4.4 5.7 0.0 4.4 5.7 0.0 3.1 1 1 1 2 2 2 0 RNA polymerase I-specific transcription-initiation factor RR_TM4-6 PF06459.12 CRK29578.1 - 9 6.0 9.2 1.4 8.7 2.1 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 HSP70 PF00012.20 CRK29580.1 - 6.8e-265 879.9 16.7 7.8e-265 879.7 16.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CRK29580.1 - 1.9e-14 53.2 4.7 1.8e-12 46.8 0.9 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 CRK29580.1 - 0.00044 20.0 0.4 0.0024 17.6 0.0 2.3 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain UVR PF02151.19 CRK29580.1 - 0.032 14.0 6.1 0.1 12.4 6.1 2.0 1 0 0 1 1 1 0 UvrB/uvrC motif Big_3_4 PF13754.6 CRK29580.1 - 0.084 12.6 0.0 4.9 6.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function Prp18 PF02840.15 CRK29580.1 - 0.12 12.4 1.0 10 6.1 0.0 2.6 2 0 0 2 2 2 0 Prp18 domain SRP68 PF16969.5 CRK29583.1 - 5.3e-206 685.9 10.9 6.1e-206 685.8 10.9 1.0 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 DUF5053 PF16476.5 CRK29583.1 - 0.0021 17.7 0.0 0.0053 16.4 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5053) PMEI PF04043.15 CRK29583.1 - 0.37 11.1 3.2 0.41 11.0 1.3 2.0 2 0 0 2 2 2 0 Plant invertase/pectin methylesterase inhibitor PPR_2 PF13041.6 CRK29584.1 - 9.4e-12 44.9 1.2 2.8e-05 24.2 0.0 6.1 5 1 1 6 6 6 2 PPR repeat family PPR PF01535.20 CRK29584.1 - 1.6e-08 34.2 0.2 0.022 15.0 0.0 6.3 7 0 0 7 7 6 1 PPR repeat PPR_1 PF12854.7 CRK29584.1 - 6e-06 25.9 0.0 0.0009 18.9 0.0 3.7 3 0 0 3 3 3 1 PPR repeat PPR_3 PF13812.6 CRK29584.1 - 2e-05 24.6 0.0 0.00063 19.8 0.0 3.0 3 0 0 3 3 3 1 Pentatricopeptide repeat domain TPR_14 PF13428.6 CRK29584.1 - 4.8e-05 23.8 5.5 1.3 10.1 0.0 6.3 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 CRK29584.1 - 0.0021 17.9 0.8 22 5.4 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 CRK29584.1 - 0.0085 16.1 5.1 3.7 7.9 0.4 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 CRK29584.1 - 0.0091 16.6 2.2 1.7 9.3 0.4 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 CRK29584.1 - 0.015 15.6 1.5 1.6 9.1 0.3 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR_long PF17177.4 CRK29584.1 - 0.029 13.7 0.0 21 4.4 0.0 3.8 4 0 0 4 4 4 0 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 CRK29584.1 - 0.1 13.1 0.6 84 3.8 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 CRK29584.1 - 3.9 7.5 6.0 23 5.0 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 CRK29584.1 - 4.4 8.2 5.2 28 5.7 0.0 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat Cutinase PF01083.22 CRK29586.1 - 1.4e-22 80.5 0.1 4.4e-22 78.9 0.1 1.8 2 0 0 2 2 2 1 Cutinase Abhydrolase_8 PF06259.12 CRK29586.1 - 0.0012 18.5 0.3 0.0022 17.6 0.3 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase Methyltransf_PK PF05891.12 CRK29588.1 - 1.2e-08 34.8 0.3 3.3e-08 33.3 0.1 1.7 1 1 1 2 2 2 1 AdoMet dependent proline di-methyltransferase DUF4210 PF13915.6 CRK29592.1 - 4.5e-33 113.7 0.2 1.1e-32 112.4 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.6 CRK29592.1 - 1.1e-24 86.3 0.2 2.7e-24 85.1 0.2 1.7 1 0 0 1 1 1 1 Chromosome segregation during meiosis CAP_N PF01213.19 CRK29594.1 - 0.12 11.8 6.5 0.21 11.1 6.5 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal RhoGAP PF00620.27 CRK29596.1 - 2.9e-45 153.8 0.0 2.9e-45 153.8 0.0 2.9 3 2 1 4 4 4 1 RhoGAP domain LIM PF00412.22 CRK29596.1 - 2.5e-12 46.8 15.1 6.3e-07 29.5 0.2 3.2 3 0 0 3 3 3 2 LIM domain IFT20 PF14931.6 CRK29596.1 - 0.0047 17.1 2.5 0.0047 17.1 2.5 2.5 2 0 0 2 2 2 1 Intraflagellar transport complex B, subunit 20 DUF4407 PF14362.6 CRK29596.1 - 0.062 12.7 6.4 0.13 11.5 6.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GIT_CC PF16559.5 CRK29596.1 - 1.1 9.1 5.0 15 5.5 0.0 3.3 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor zf-ribbon_3 PF13248.6 CRK29596.1 - 1.3 8.6 12.5 0.82 9.2 0.0 3.7 3 1 0 3 3 3 0 zinc-ribbon domain Med11 PF10280.9 CRK29596.1 - 1.7 9.1 8.4 0.13 12.8 2.2 2.4 2 0 0 2 2 2 0 Mediator complex protein Zn-ribbon_8 PF09723.10 CRK29596.1 - 2.3 8.4 18.4 1.1 9.4 1.2 4.1 4 0 0 4 4 4 0 Zinc ribbon domain Desulfoferrod_N PF06397.12 CRK29596.1 - 2.3 7.9 8.4 18 5.0 0.9 3.5 2 1 1 3 3 3 0 Desulfoferrodoxin, N-terminal domain CENP-F_leu_zip PF10473.9 CRK29596.1 - 5.6 7.0 22.2 9.2 6.3 8.2 2.8 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Laminin_II PF06009.12 CRK29596.1 - 6.7 6.7 10.4 0.56 10.2 1.6 2.4 2 0 0 2 2 2 0 Laminin Domain II SlyX PF04102.12 CRK29596.1 - 8.5 7.1 10.0 0.58 10.8 2.0 3.2 2 1 0 2 2 2 0 SlyX HlyIII PF03006.20 CRK29598.1 - 4.8e-54 183.4 18.1 5.7e-54 183.2 18.1 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF1986 PF09342.11 CRK29598.1 - 0.09 13.2 0.2 0.2 12.0 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1986) ATPase_gene1 PF09527.10 CRK29598.1 - 0.11 12.7 4.9 0.84 9.9 2.9 2.8 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter LON_substr_bdg PF02190.16 CRK29600.1 - 2.9e-24 86.1 0.0 5.5e-24 85.2 0.0 1.5 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 CRK29600.1 - 1.9e-15 57.5 0.0 4.2e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CRK29600.1 - 3.5e-06 27.1 0.0 7.7e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CRK29600.1 - 5.9e-06 26.8 0.1 2.2e-05 24.9 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.17 CRK29600.1 - 3.8e-05 23.5 0.0 8.7e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.12 CRK29600.1 - 0.0001 22.1 0.0 0.00023 20.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 CRK29600.1 - 0.0002 21.3 0.0 0.00037 20.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CRK29600.1 - 0.00088 19.6 0.0 0.046 14.0 0.0 2.5 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 CRK29600.1 - 0.0018 17.5 1.0 0.005 16.1 0.0 1.8 2 0 0 2 2 2 1 TIP49 P-loop domain NACHT PF05729.12 CRK29600.1 - 0.0074 16.2 0.0 0.03 14.2 0.0 2.0 2 0 0 2 2 1 1 NACHT domain AAA_18 PF13238.6 CRK29600.1 - 0.011 16.3 0.0 0.027 15.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CRK29600.1 - 0.02 15.3 0.0 0.044 14.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 CRK29600.1 - 0.03 14.5 0.0 0.069 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 CRK29600.1 - 0.034 14.0 0.1 0.11 12.5 0.0 1.8 1 1 1 2 2 2 0 NTPase Ino80_Iec3 PF14612.6 CRK29600.1 - 0.04 14.6 1.0 0.069 13.8 1.0 1.3 1 0 0 1 1 1 0 IEC3 subunit of the Ino80 complex, chromatin re-modelling TsaE PF02367.17 CRK29600.1 - 0.05 13.6 0.0 0.092 12.7 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_2 PF07724.14 CRK29600.1 - 0.051 13.7 0.0 0.12 12.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) Rad17 PF03215.15 CRK29600.1 - 0.052 13.5 0.0 0.097 12.6 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain RsgA_GTPase PF03193.16 CRK29600.1 - 0.057 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase Mg_chelatase PF01078.21 CRK29600.1 - 0.065 12.6 0.2 0.14 11.5 0.2 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NB-ARC PF00931.22 CRK29600.1 - 0.074 12.2 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_23 PF13476.6 CRK29600.1 - 0.075 13.5 0.0 0.075 13.5 0.0 2.4 1 1 1 2 2 1 0 AAA domain AAA_14 PF13173.6 CRK29600.1 - 0.076 13.0 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CRK29600.1 - 0.087 12.5 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 CRK29600.1 - 0.09 12.3 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 CRK29600.1 - 0.11 11.8 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_PrkA PF08298.11 CRK29600.1 - 0.13 11.1 0.1 3.4 6.5 0.0 2.1 1 1 1 2 2 2 0 PrkA AAA domain AAA_17 PF13207.6 CRK29600.1 - 0.16 12.4 1.2 0.76 10.2 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CRK29600.1 - 0.22 11.0 0.0 0.38 10.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region BSP PF04450.12 CRK29602.1 - 9.2e-47 159.5 0.0 1.1e-46 159.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase of plants and bacteria SprT-like PF10263.9 CRK29602.1 - 0.18 11.6 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 SprT-like family Iso_dh PF00180.20 CRK29606.1 - 7e-95 318.1 0.0 1.2e-94 317.4 0.0 1.3 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Phage_30_3 PF08010.11 CRK29606.1 - 0.058 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage protein GP30.3 Sec5 PF15469.6 CRK29608.1 - 1.9e-37 128.9 0.0 5.1e-37 127.5 0.0 1.8 1 0 0 1 1 1 1 Exocyst complex component Sec5 Vps51 PF08700.11 CRK29608.1 - 0.0004 20.4 1.5 0.0014 18.7 0.1 2.7 2 0 0 2 2 2 1 Vps51/Vps67 Sec15 PF04091.12 CRK29608.1 - 0.00058 19.4 0.1 0.0011 18.5 0.1 1.3 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like RINT1_TIP1 PF04437.13 CRK29608.1 - 0.036 13.0 0.2 0.063 12.2 0.2 1.3 1 0 0 1 1 1 0 RINT-1 / TIP-1 family Tn7_TnsC_Int PF11426.8 CRK29608.1 - 0.45 10.7 2.3 4.5 7.5 0.1 3.3 3 0 0 3 3 3 0 Tn7 transposition regulator TnsC Spt4 PF06093.13 CRK29611.1 - 0.011 15.8 0.1 3.9 7.6 0.4 3.7 4 0 0 4 4 4 0 Spt4/RpoE2 zinc finger DUF2285 PF10074.9 CRK29611.1 - 0.11 13.1 1.4 0.53 11.0 1.4 2.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2285) Zn_clus PF00172.18 CRK29611.1 - 0.15 12.2 6.7 0.37 11.0 6.7 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain IPP-2 PF04979.14 CRK29611.1 - 0.86 10.3 5.6 0.15 12.8 1.5 1.8 2 0 0 2 2 2 0 Protein phosphatase inhibitor 2 (IPP-2) EccE PF11203.8 CRK29611.1 - 2 8.8 9.0 0.98 9.8 0.8 3.4 3 0 0 3 3 3 0 Putative type VII ESX secretion system translocon, EccE Glyco_hydro_92 PF07971.12 CRK29613.1 - 3.3e-138 461.5 0.0 4.1e-138 461.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 CRK29613.1 - 9.7e-45 153.3 4.1 1.6e-44 152.6 4.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Gram_pos_anchor PF00746.21 CRK29613.1 - 1.5 8.8 3.2 12 6.0 1.1 2.5 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Solute_trans_a PF03619.16 CRK29614.1 - 1.7e-63 214.7 5.0 9.4e-53 179.4 0.6 2.3 1 1 1 2 2 2 2 Organic solute transporter Ostalpha COPI_assoc PF08507.10 CRK29614.1 - 0.081 13.0 1.7 5.1 7.2 0.0 2.3 2 0 0 2 2 2 0 COPI associated protein GTP_EFTU PF00009.27 CRK29617.1 - 1.1e-112 374.2 4.0 5e-65 218.7 0.1 2.7 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 CRK29617.1 - 7.8e-30 103.2 0.0 1.8e-29 101.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 CRK29617.1 - 7.5e-23 80.4 0.0 3e-21 75.2 0.0 3.0 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 CRK29617.1 - 7.3e-12 45.5 0.1 2.1e-11 44.0 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 CRK29617.1 - 3.1e-11 43.2 0.0 8.7e-11 41.8 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 CRK29617.1 - 4.6e-07 29.9 2.0 0.011 15.7 0.2 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase PWI PF01480.17 CRK29617.1 - 2.1e-05 24.7 0.4 6.8e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 PWI domain RRM_1 PF00076.22 CRK29617.1 - 0.023 14.5 1.1 0.24 11.3 0.0 3.0 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PduV-EutP PF10662.9 CRK29617.1 - 0.032 14.0 0.0 1.4 8.6 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MTHFR PF02219.17 CRK29620.1 - 2.3e-112 375.0 0.0 4e-112 374.2 0.0 1.3 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase DUF3425 PF11905.8 CRK29620.1 - 1.4e-14 54.1 0.0 5.1e-14 52.3 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Sh_2 PF17512.2 CRK29622.1 - 0.00033 20.5 2.3 0.00057 19.7 2.3 1.3 1 0 0 1 1 1 1 Metapneumovirus Small hydrophobic protein PAN_1 PF00024.26 CRK29622.1 - 0.0023 17.8 0.0 0.0068 16.3 0.0 1.7 1 0 0 1 1 1 1 PAN domain Tad PF13400.6 CRK29622.1 - 0.055 13.8 4.7 0.14 12.5 4.7 1.7 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like MFS_1 PF07690.16 CRK29625.1 - 1.7e-25 89.8 31.9 2.7e-25 89.0 31.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 CRK29625.1 - 0.032 13.1 1.7 0.23 10.3 0.3 2.2 2 0 0 2 2 2 0 MFS_1 like family 4HBT PF03061.22 CRK29629.1 - 2.7e-09 37.2 0.0 4.2e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily Ribonuclease_3 PF00636.26 CRK29631.1 - 3.2e-45 153.0 0.0 2.8e-22 79.3 0.0 2.8 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 CRK29631.1 - 3.5e-25 88.6 0.0 7.5e-10 39.1 0.0 3.6 3 0 0 3 3 3 3 Ribonuclease-III-like Dicer_dimer PF03368.14 CRK29631.1 - 2.8e-20 72.3 0.0 1.2e-17 63.9 0.0 3.0 2 0 0 2 2 2 1 Dicer dimerisation domain Helicase_C PF00271.31 CRK29631.1 - 3.6e-18 65.9 0.0 9.7e-18 64.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CRK29631.1 - 7.9e-14 52.0 0.0 2.4e-13 50.5 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CRK29631.1 - 1e-11 44.9 0.0 2.1e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2192 PF09958.9 CRK29631.1 - 0.0014 18.2 0.1 0.0027 17.3 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2192) AAA_22 PF13401.6 CRK29631.1 - 0.016 15.5 0.1 0.13 12.5 0.1 2.4 1 1 0 1 1 1 0 AAA domain TF_AP-2 PF03299.14 CRK29631.1 - 0.067 13.1 1.5 2.8 7.9 0.0 3.2 3 0 0 3 3 3 0 Transcription factor AP-2 TAP42 PF04177.12 CRK29632.1 - 3.8e-125 417.3 2.0 7e-99 330.9 0.0 2.0 2 0 0 2 2 2 2 TAP42-like family ELM2 PF01448.24 CRK29632.1 - 0.01 16.6 2.5 1.3 9.9 0.0 3.3 3 0 0 3 3 3 0 ELM2 domain CPSase_sm_chain PF00988.22 CRK29641.1 - 1.5e-46 157.4 0.0 1.9e-46 157.0 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain CPSase_L_D2 PF02786.17 CRK29643.1 - 1.3e-112 374.4 0.2 4.2e-83 278.0 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 CRK29643.1 - 3.5e-39 133.9 0.0 9.7e-39 132.5 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 CRK29643.1 - 4.1e-31 108.2 0.0 1.3e-30 106.6 0.0 1.9 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 CRK29643.1 - 6.6e-22 77.5 0.0 2.9e-21 75.4 0.0 2.2 2 0 0 2 2 2 1 MGS-like domain GATase PF00117.28 CRK29643.1 - 2.9e-21 76.1 0.0 5.8e-21 75.1 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Dala_Dala_lig_C PF07478.13 CRK29643.1 - 1.7e-17 63.6 1.1 6.5e-09 35.6 0.2 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 CRK29643.1 - 7e-15 55.0 0.1 4.5e-07 29.6 0.1 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 CRK29643.1 - 1.7e-10 40.7 0.0 1.8e-05 24.5 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon OTCace_N PF02729.21 CRK29643.1 - 3.1e-10 40.3 0.0 4.3e-08 33.3 0.0 2.6 1 1 1 2 2 2 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain ATP-grasp_3 PF02655.14 CRK29643.1 - 5.6e-06 26.5 2.1 0.0072 16.4 0.1 2.9 3 0 0 3 3 3 2 ATP-grasp domain PNP_phzG_C PF10590.9 CRK29645.1 - 7.3e-21 74.0 2.3 1.6e-20 72.9 1.5 2.1 2 0 0 2 2 2 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Putative_PNPOx PF01243.20 CRK29645.1 - 6.1e-18 64.8 0.1 1.1e-17 64.0 0.1 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.7 CRK29645.1 - 0.00026 21.5 0.0 0.00049 20.7 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Cyclin_N PF00134.23 CRK29647.1 - 4e-06 26.6 0.0 1.2e-05 25.1 0.0 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain DUF5457 PF17540.2 CRK29647.1 - 0.08 13.1 0.1 0.13 12.4 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5457) Methyltransf_23 PF13489.6 CRK29683.1 - 1.9e-12 47.3 0.0 2.3e-12 47.1 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK29683.1 - 0.0018 18.1 0.0 0.0027 17.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CRK29683.1 - 0.0069 17.0 0.0 0.023 15.4 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK29683.1 - 0.064 14.0 0.0 0.14 12.9 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 CRK29683.1 - 0.14 12.9 0.0 0.49 11.1 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain DUF3435 PF11917.8 CRK29684.1 - 1.1e-57 195.9 0.2 1.1e-57 195.9 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3435) RRP36 PF06102.12 CRK29684.1 - 0.001 19.1 2.2 0.001 19.1 2.2 1.9 2 0 0 2 2 2 1 rRNA biogenesis protein RRP36 PNP_UDP_1 PF01048.20 CRK29685.1 - 5.9e-10 38.8 0.3 1.3e-09 37.6 0.3 1.5 1 1 0 1 1 1 1 Phosphorylase superfamily DnaJ PF00226.31 CRK29687.1 - 0.0015 18.6 0.1 0.0019 18.3 0.1 1.2 1 0 0 1 1 1 1 DnaJ domain OTT_1508_deam PF14441.6 CRK29688.1 - 9.9e-16 57.5 2.0 1.3e-15 57.1 0.9 1.9 2 0 0 2 2 2 1 OTT_1508-like deaminase DUF2267 PF10025.9 CRK29689.1 - 0.013 15.8 0.2 0.023 15.0 0.2 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) Baculo_PEP_C PF04513.12 CRK29689.1 - 0.056 13.5 0.2 0.1 12.6 0.2 1.5 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus PilJ PF13675.6 CRK29689.1 - 0.1 12.7 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term RNA_pol_Rpb8 PF03870.15 CRK29690.1 - 4.8e-38 130.5 0.0 8.1e-38 129.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNase_PH PF01138.21 CRK29690.1 - 2.5e-14 53.9 2.1 3.9e-10 40.4 0.1 3.1 2 1 1 3 3 3 2 3' exoribonuclease family, domain 1 SDA1 PF05285.12 CRK29690.1 - 0.19 11.1 0.3 0.41 10.0 0.3 1.4 1 0 0 1 1 1 0 SDA1 PAXNEB PF05625.11 CRK29691.1 - 1.9e-40 139.2 0.0 2.5e-40 138.8 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein Big_4 PF07532.11 CRK29691.1 - 0.008 15.9 0.0 0.14 11.9 0.0 2.2 2 0 0 2 2 2 1 Bacterial Ig-like domain (group 4) Anp1 PF03452.14 CRK29692.1 - 1.9e-113 378.2 0.1 3.7e-113 377.3 0.0 1.5 2 0 0 2 2 2 1 Anp1 TP53IP5 PF15331.6 CRK29692.1 - 0.52 10.4 4.6 0.78 9.8 4.6 1.2 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Sec7 PF01369.20 CRK29693.1 - 1.4e-65 220.5 0.0 8.1e-65 217.9 0.0 2.3 3 0 0 3 3 3 1 Sec7 domain PolyA_pol PF01743.20 CRK29693.1 - 1.7e-24 86.6 0.1 1.7e-24 86.6 0.1 2.4 2 0 0 2 2 2 1 Poly A polymerase head domain Sec7_N PF12783.7 CRK29693.1 - 6.4e-17 61.9 0.1 5.3e-16 58.9 0.0 2.6 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal RRM_1 PF00076.22 CRK29693.1 - 6.2e-15 54.8 1.3 7.2e-11 41.8 0.2 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tti2 PF10521.9 CRK29693.1 - 3.1e-13 49.9 0.0 5.9e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Tti2 family Suf PF05843.14 CRK29693.1 - 3.2e-08 33.9 6.8 0.27 11.2 0.6 6.9 4 2 2 6 6 6 2 Suppressor of forked protein (Suf) PolyA_pol_RNAbd PF12627.7 CRK29693.1 - 9.7e-07 28.5 0.0 3.2e-06 26.8 0.0 1.9 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A RRM_5 PF13893.6 CRK29693.1 - 1.7e-06 27.7 0.0 5.4e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPR_15 PF13429.6 CRK29693.1 - 0.00018 20.8 3.7 0.00095 18.5 0.4 3.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 CRK29693.1 - 0.0049 17.6 24.3 13 6.9 0.2 10.9 12 0 0 12 12 9 1 Tetratricopeptide repeat NRDE-2 PF08424.10 CRK29693.1 - 0.011 14.8 2.7 0.17 11.0 0.1 3.8 3 1 1 4 4 4 0 NRDE-2, necessary for RNA interference DUF4523 PF15023.6 CRK29693.1 - 0.023 14.5 0.0 0.081 12.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4523) TPR_8 PF13181.6 CRK29693.1 - 0.075 13.3 1.9 21 5.7 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 CRK29693.1 - 0.13 12.2 8.5 1.5 8.8 0.0 5.3 7 0 0 7 7 7 0 Mad3/BUB1 homology region 1 ATP-synt_D PF01813.17 CRK29694.1 - 1.3e-42 145.9 9.3 1.8e-30 106.3 0.1 3.1 2 1 1 3 3 3 3 ATP synthase subunit D RICH PF05062.12 CRK29694.1 - 0.02 15.2 0.4 0.064 13.6 0.4 1.8 1 0 0 1 1 1 0 RICH domain ZapD PF07072.11 CRK29694.1 - 0.064 13.0 0.9 0.29 10.8 0.6 1.9 2 0 0 2 2 2 0 Cell division protein Syja_N PF02383.18 CRK29696.1 - 2.2e-76 257.2 0.0 4.2e-76 256.3 0.0 1.5 1 0 0 1 1 1 1 SacI homology domain SAM_PNT PF02198.16 CRK29696.1 - 0.081 12.9 0.1 6.6 6.8 0.1 2.7 2 0 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain Melibiase_2 PF16499.5 CRK29697.1 - 1.1e-15 57.5 0.1 1.5e-15 57.1 0.1 1.1 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 CRK29697.1 - 9.1e-10 38.5 0.1 7e-09 35.6 0.0 2.3 3 0 0 3 3 3 1 Alpha galactosidase C-terminal beta sandwich domain MFS_1 PF07690.16 CRK29698.1 - 1.1e-16 60.8 19.3 5e-13 48.7 10.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MWFE PF15879.5 CRK29698.1 - 0.38 11.0 0.1 0.38 11.0 0.1 2.6 3 1 1 4 4 4 0 NADH-ubiquinone oxidoreductase MWFE subunit MFS_1 PF07690.16 CRK29699.1 - 2.5e-25 89.1 33.7 2.9e-20 72.5 18.9 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily PUCC PF03209.15 CRK29699.1 - 0.032 13.3 0.4 0.032 13.3 0.4 2.4 2 1 0 2 2 2 0 PUCC protein Adeno_E3B PF03376.14 CRK29699.1 - 0.69 10.2 3.8 65 3.9 0.0 3.9 4 0 0 4 4 4 0 Adenovirus E3B protein F-box-like PF12937.7 CRK29701.1 - 0.00077 19.3 1.6 0.0011 18.8 0.2 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CRK29701.1 - 0.025 14.5 0.1 0.096 12.6 0.1 2.1 1 0 0 1 1 1 0 F-box domain SBP_bac_3 PF00497.20 CRK29702.1 - 0.0009 18.7 0.0 0.0072 15.8 0.0 2.0 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 NMT1 PF09084.11 CRK29702.1 - 0.0021 18.0 0.0 0.025 14.5 0.0 2.1 1 1 1 2 2 2 2 NMT1/THI5 like Peptidase_M43 PF05572.13 CRK29703.1 - 4.7e-07 29.8 0.0 9.8e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 CRK29703.1 - 0.00082 19.9 0.0 0.0036 17.8 0.0 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 CRK29703.1 - 0.0043 17.2 0.2 0.017 15.3 0.1 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 CRK29703.1 - 0.036 13.7 0.1 0.096 12.3 0.2 1.7 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 CRK29703.1 - 0.036 13.9 0.1 0.07 13.0 0.1 1.3 1 0 0 1 1 1 0 Matrixin Peptidase_M66 PF10462.9 CRK29703.1 - 0.11 11.5 0.2 0.17 10.8 0.2 1.2 1 0 0 1 1 1 0 Peptidase M66 DUF4953 PF16313.5 CRK29703.1 - 0.11 11.7 0.6 0.2 10.8 0.6 1.3 1 0 0 1 1 1 0 Met-zincin GMC_oxred_N PF00732.19 CRK29705.1 - 2.5e-56 191.2 0.0 3.2e-56 190.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CRK29705.1 - 1.1e-37 129.7 0.0 1.9e-37 129.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 CRK29705.1 - 0.0016 17.6 0.2 0.0027 16.8 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 CRK29705.1 - 0.0064 16.1 0.9 0.025 14.1 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CRK29705.1 - 0.0075 15.5 0.6 0.052 12.8 0.1 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CRK29705.1 - 0.051 13.8 0.4 0.17 12.1 0.4 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Dmrt1 PF12374.8 CRK29705.1 - 0.16 12.4 0.0 0.38 11.2 0.0 1.6 1 0 0 1 1 1 0 Double-sex mab3 related transcription factor 1 CHRD PF07452.12 CRK29706.1 - 1.4e-11 45.4 0.0 3e-11 44.3 0.0 1.6 1 1 1 2 2 2 1 CHRD domain MFS_1 PF07690.16 CRK29726.1 - 0.00018 20.6 16.6 0.0014 17.6 5.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_M48_N PF16491.5 CRK29726.1 - 0.049 13.5 1.7 0.081 12.8 1.7 1.5 1 0 0 1 1 1 0 CAAX prenyl protease N-terminal, five membrane helices 7tm_6 PF02949.20 CRK29726.1 - 0.42 9.7 2.0 0.53 9.3 2.0 1.2 1 0 0 1 1 1 0 7tm Odorant receptor Aminotran_3 PF00202.21 CRK29727.1 - 3.7e-38 131.2 0.0 1.2e-18 67.0 0.0 3.0 2 1 0 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.6 CRK29727.1 - 8.2e-14 51.9 0.0 1.4e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain Aminotran_1_2 PF00155.21 CRK29729.1 - 5e-14 52.3 0.0 2e-09 37.1 0.0 2.1 1 1 1 2 2 2 2 Aminotransferase class I and II Fungal_trans PF04082.18 CRK29731.1 - 1.8e-44 151.8 0.0 2.8e-44 151.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain SGS PF05002.15 CRK29731.1 - 5.2e-28 97.0 4.0 1.4e-27 95.6 4.0 1.8 1 0 0 1 1 1 1 SGS domain Aminotran_1_2 PF00155.21 CRK29731.1 - 3.1e-15 56.2 0.0 5.7e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II CS PF04969.16 CRK29731.1 - 1.1e-09 39.2 0.0 1.8e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 CS domain SQHop_cyclase_C PF13243.6 CRK29731.1 - 1.8e-09 37.1 1.0 4.4e-09 35.9 0.1 1.9 2 0 0 2 2 2 1 Squalene-hopene cyclase C-terminal domain zf-C2H2 PF00096.26 CRK29731.1 - 0.0069 16.8 0.2 0.0069 16.8 0.2 2.3 2 0 0 2 2 2 1 Zinc finger, C2H2 type Chromadorea_ALT PF05535.12 CRK29731.1 - 0.027 14.7 0.6 0.9 9.8 0.3 3.0 3 0 0 3 3 3 0 Chromadorea ALT protein Cys_Met_Meta_PP PF01053.20 CRK29731.1 - 0.095 11.2 0.0 0.34 9.4 0.0 1.8 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme DUF5326 PF17260.2 CRK29731.1 - 0.14 12.3 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5326) Lipase_GDSL_2 PF13472.6 CRK29734.1 - 5.8e-12 46.4 0.8 7.9e-12 45.9 0.8 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 CRK29734.1 - 0.00036 20.5 0.4 0.00076 19.5 0.4 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase tRNA_int_endo PF01974.17 CRK29735.1 - 3.7e-19 68.6 0.0 8.3e-19 67.4 0.0 1.6 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 CRK29735.1 - 0.04 13.6 0.1 0.097 12.4 0.0 1.6 2 0 0 2 2 2 0 tRNA intron endonuclease, N-terminal domain Glyco_transf_21 PF13506.6 CRK29737.1 - 7e-13 48.4 0.0 4.7e-05 22.9 0.0 3.3 3 0 0 3 3 3 3 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 CRK29737.1 - 7.3e-07 29.3 0.0 1.7e-05 24.8 0.0 2.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 CRK29737.1 - 0.12 12.2 0.0 0.53 10.1 0.0 2.0 1 1 0 1 1 1 0 Glycosyl transferase family 2 Glyco_hydro_28 PF00295.17 CRK29739.1 - 3.5e-37 128.2 4.1 1.6e-36 126.0 1.9 2.0 1 1 1 2 2 2 2 Glycosyl hydrolases family 28 Beta_helix PF13229.6 CRK29739.1 - 0.031 14.1 6.3 0.016 15.1 3.2 2.0 1 1 0 1 1 1 0 Right handed beta helix region Pribosyl_synth PF14572.6 CRK29761.1 - 3.7e-26 92.3 4.2 1e-19 71.3 1.9 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 CRK29761.1 - 2.2e-22 79.2 0.1 5.9e-22 77.8 0.0 1.7 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 CRK29761.1 - 7e-15 54.9 0.5 1.1e-14 54.3 0.5 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CRK29761.1 - 0.0029 17.1 0.4 0.0046 16.4 0.4 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DNA_pol_A_exo1 PF01612.20 CRK29761.1 - 0.0035 17.1 0.0 0.0066 16.2 0.0 1.4 1 0 0 1 1 1 1 3'-5' exonuclease Pkinase PF00069.25 CRK29761.1 - 0.0059 16.0 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Sec8_exocyst PF04048.14 CRK29763.1 - 2.5e-48 163.6 0.5 6.1e-48 162.3 0.5 1.7 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 CRK29763.1 - 6.8e-10 38.7 0.5 1.4e-09 37.7 0.5 1.4 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex RAI1 PF08652.11 CRK29765.1 - 3e-27 94.6 0.0 1.8e-26 92.1 0.0 2.3 3 0 0 3 3 3 1 RAI1 like PD-(D/E)XK nuclease Glycos_transf_2 PF00535.26 CRK29789.1 - 6.4e-21 74.9 0.1 1e-20 74.2 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 CRK29789.1 - 2.8e-18 66.0 0.0 4.1e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.6 CRK29789.1 - 4e-18 66.0 0.6 4e-18 66.0 0.6 2.9 2 1 1 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 CRK29789.1 - 5.5e-14 52.6 0.0 7.8e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Cellulose_synt PF03552.14 CRK29789.1 - 1.1e-07 30.8 1.1 0.0061 15.1 0.1 3.1 1 1 1 3 3 3 2 Cellulose synthase DUF5553 PF17707.1 CRK29791.1 - 0.19 11.2 0.0 0.21 11.0 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5553) AtuA PF07287.11 CRK29794.1 - 5.4e-99 331.2 0.3 6.9e-99 330.9 0.3 1.0 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA adh_short_C2 PF13561.6 CRK29796.1 - 1.6e-60 204.6 0.3 1.9e-60 204.3 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRK29796.1 - 1.4e-43 148.6 0.2 1.6e-43 148.4 0.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CRK29796.1 - 2.7e-09 37.2 0.7 3.9e-09 36.7 0.7 1.1 1 0 0 1 1 1 1 KR domain AMP-binding PF00501.28 CRK29798.1 - 1.7e-64 218.0 0.3 1.1e-55 189.0 0.0 2.1 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 CRK29798.1 - 4e-12 46.9 0.0 9.3e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain YabA PF06156.13 CRK29798.1 - 0.017 15.8 0.3 0.038 14.6 0.3 1.5 1 0 0 1 1 1 0 Initiation control protein YabA ZapB PF06005.12 CRK29798.1 - 0.1 13.0 3.8 0.087 13.3 2.2 1.7 2 0 0 2 2 2 0 Cell division protein ZapB Csm1_N PF18504.1 CRK29798.1 - 0.19 12.1 1.9 0.48 10.8 1.9 1.7 1 0 0 1 1 1 0 Csm1 N-terminal domain TolA_bind_tri PF16331.5 CRK29798.1 - 0.89 9.7 5.3 1.9 8.7 5.3 1.5 1 0 0 1 1 1 0 TolA binding protein trimerisation TRI12 PF06609.13 CRK29800.1 - 9.3e-65 219.2 17.6 1.5e-64 218.5 17.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ECH_1 PF00378.20 CRK29800.1 - 4.8e-50 170.2 0.1 7.3e-50 169.6 0.1 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CRK29800.1 - 6e-24 85.2 0.0 8.6e-24 84.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase MFS_1 PF07690.16 CRK29800.1 - 2.8e-21 75.8 48.8 1.4e-20 73.5 46.4 3.2 3 1 0 3 3 3 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK29800.1 - 0.0066 15.4 27.2 0.046 12.6 11.9 3.5 2 1 0 2 2 2 2 Sugar (and other) transporter Transp_inhibit PF18791.1 CRK29800.1 - 0.38 10.3 1.7 8.6 6.0 0.1 2.5 2 0 0 2 2 2 0 Transport inhibitor response 1 protein domain DUF373 PF04123.13 CRK29800.1 - 9.9 5.5 12.4 0.4 10.1 6.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF373) ECH_1 PF00378.20 CRK29803.1 - 1.7e-42 145.5 0.0 2.3e-42 145.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CRK29803.1 - 2.3e-17 63.5 0.1 2.5e-15 56.8 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase MaoC_dehydratas PF01575.19 CRK29805.1 - 1.1e-24 86.3 0.0 1.7e-24 85.8 0.0 1.2 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 CRK29805.1 - 1.5e-06 28.4 0.0 0.0003 20.9 0.0 2.7 3 0 0 3 3 3 2 N-terminal half of MaoC dehydratase AtuA PF07287.11 CRK29806.1 - 1.9e-43 148.6 0.0 2.5e-43 148.2 0.0 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA AtuA PF07287.11 CRK29808.1 - 1.3e-74 251.0 1.0 1.5e-74 250.9 1.0 1.0 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA DNAPolymera_Pol PF11590.8 CRK29808.1 - 0.14 12.1 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase catalytic subunit Pol AMP-binding PF00501.28 CRK29810.1 - 1.7e-58 198.2 0.0 1.5e-43 149.0 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 CRK29810.1 - 5.1e-06 27.4 0.0 1.1e-05 26.3 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ABM PF03992.16 CRK29812.1 - 1.5e-07 31.5 2.1 0.012 15.7 0.9 3.1 2 1 0 2 2 2 2 Antibiotic biosynthesis monooxygenase DUF4578 PF15147.6 CRK29812.1 - 0.11 13.4 0.1 0.4 11.6 0.0 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4578) AtuA PF07287.11 CRK29814.1 - 1.2e-125 418.9 0.5 1.9e-125 418.2 0.5 1.3 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA Peptidase_M28 PF04389.17 CRK29814.1 - 1.4e-15 57.5 0.0 2.3e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 STAT2_C PF12188.8 CRK29814.1 - 0.085 12.8 0.1 0.33 10.9 0.1 2.0 1 0 0 1 1 1 0 Signal transducer and activator of transcription 2 C terminal TPR_12 PF13424.6 CRK29835.1 - 0.023 15.0 18.8 2 8.8 0.0 6.6 5 1 0 6 6 6 0 Tetratricopeptide repeat DUF3856 PF12968.7 CRK29835.1 - 0.19 11.8 1.3 3.1 7.9 0.1 2.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF3856) RPN7 PF10602.9 CRK29835.1 - 0.22 11.2 2.8 13 5.5 0.1 3.7 2 2 0 2 2 2 0 26S proteasome subunit RPN7 TPR_19 PF14559.6 CRK29835.1 - 0.27 11.8 12.8 2.6 8.6 0.2 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF5321 PF17254.2 CRK29836.1 - 1e-59 200.5 0.3 1.3e-59 200.2 0.3 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5321) DUF3708 PF12501.8 CRK29836.1 - 0.12 12.1 0.1 0.19 11.5 0.1 1.3 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter FGGY_C PF02782.16 CRK29838.1 - 6.1e-26 91.4 0.0 1.2e-25 90.4 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 CRK29838.1 - 4.5e-17 62.4 0.0 8.8e-15 54.9 0.0 2.5 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain DUF2385 PF09539.10 CRK29838.1 - 0.16 12.5 0.0 0.55 10.8 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2385) adh_short PF00106.25 CRK29840.1 - 1.1e-39 136.0 0.0 1.3e-39 135.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK29840.1 - 3.1e-28 98.9 0.0 4e-28 98.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK29840.1 - 1.8e-10 41.0 0.0 2.8e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 CRK29840.1 - 2.4e-06 27.6 0.0 2.9e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 CRK29840.1 - 8e-06 25.5 0.0 1.9e-05 24.3 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 CRK29840.1 - 0.00014 21.4 0.0 0.00018 21.0 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NmrA PF05368.13 CRK29840.1 - 0.00075 19.1 0.0 0.0043 16.6 0.0 1.9 2 0 0 2 2 2 1 NmrA-like family ADH_zinc_N PF00107.26 CRK29840.1 - 0.001 19.1 0.1 0.0028 17.7 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 CRK29841.1 - 2.5e-26 92.4 0.0 2.9e-25 88.9 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK29841.1 - 1.6e-13 50.8 0.0 9.1e-13 48.3 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 CRK29841.1 - 1.5e-06 27.8 0.0 2.2e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 CRK29841.1 - 1.3e-05 25.2 0.0 2.1e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 CRK29841.1 - 0.00017 21.1 0.0 0.009 15.4 0.0 2.0 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase AdoHcyase_NAD PF00670.21 CRK29841.1 - 0.035 14.2 0.3 0.062 13.4 0.3 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain HEAT PF02985.22 CRK29844.1 - 3.5e-07 29.9 0.5 1.7 9.1 0.0 5.6 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 CRK29844.1 - 0.0017 18.7 4.9 0.084 13.3 0.6 4.8 4 1 1 5 5 5 2 HEAT repeats TetR_C_28 PF17937.1 CRK29844.1 - 0.019 15.4 0.1 3.7 8.1 0.0 3.3 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF3135 PF11333.8 CRK29844.1 - 0.061 13.6 0.6 2.2 8.6 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3135) Cnd1 PF12717.7 CRK29844.1 - 0.11 12.5 4.5 39 4.2 0.0 4.8 4 1 1 5 5 5 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 CRK29844.1 - 0.33 11.5 0.0 0.33 11.5 0.0 4.5 7 0 0 7 7 7 0 HEAT-like repeat IFRD PF05004.13 CRK29844.1 - 0.63 9.1 0.0 0.63 9.1 0.0 4.7 5 0 0 5 5 5 0 Interferon-related developmental regulator (IFRD) Pkinase PF00069.25 CRK29845.1 - 8.2e-68 228.6 0.0 1.1e-67 228.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK29845.1 - 4.1e-49 167.2 0.0 6.5e-49 166.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CRK29845.1 - 4.7e-07 29.4 0.0 8.7e-05 22.0 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 CRK29845.1 - 0.0057 15.5 0.1 0.013 14.3 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Glyco_hydro_28 PF00295.17 CRK29846.1 - 7.1e-23 81.2 2.5 1.1e-22 80.6 2.5 1.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 DUF4930 PF16284.5 CRK29846.1 - 0.16 11.9 0.3 0.26 11.2 0.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4930) DUF4863 PF16155.5 CRK29847.1 - 2.2e-70 235.4 0.0 2.5e-70 235.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4863) LCIB_C_CA PF18599.1 CRK29847.1 - 0.14 11.5 0.1 0.2 11.0 0.1 1.2 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases DUF1737 PF08410.10 CRK29847.1 - 0.18 11.6 2.0 1.3 8.9 0.0 2.9 3 1 1 4 4 4 0 Domain of unknown function (DUF1737) Glyco_hydro_6 PF01341.17 CRK29849.1 - 2.8e-94 316.3 0.1 4.3e-94 315.7 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 COesterase PF00135.28 CRK29849.1 - 1.3e-78 265.2 0.0 2.2e-78 264.4 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CRK29849.1 - 0.017 15.0 0.4 0.088 12.7 0.4 2.2 1 1 0 1 1 1 0 alpha/beta hydrolase fold Gly_transf_sug PF04488.15 CRK29850.1 - 3.5e-16 59.6 0.1 6.1e-16 58.8 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 CRK29850.1 - 0.016 14.6 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein RTA1 PF04479.13 CRK29851.1 - 2.6e-96 321.2 11.4 1.1e-63 214.6 4.1 2.2 2 0 0 2 2 2 2 RTA1 like protein Abhydrolase_6 PF12697.7 CRK29851.1 - 5.8e-10 40.2 0.3 5.8e-10 40.2 0.3 2.9 2 1 1 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CRK29851.1 - 7.7e-10 38.8 0.0 3.7e-09 36.6 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CRK29851.1 - 0.00076 18.8 0.0 0.0022 17.3 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 EthD PF07110.11 CRK29851.1 - 0.0011 20.0 0.1 0.82 10.9 0.0 2.9 2 0 0 2 2 2 1 EthD domain Esterase PF00756.20 CRK29851.1 - 0.018 14.7 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 Putative esterase ABM PF03992.16 CRK29851.1 - 0.064 13.4 0.0 0.22 11.6 0.0 2.0 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase NuDC PF16273.5 CRK29851.1 - 0.12 12.9 0.6 0.21 12.1 0.6 1.3 1 0 0 1 1 1 0 Nuclear distribution C domain DUF1899 PF08953.11 CRK29851.1 - 6.3 6.8 5.2 47 4.0 0.5 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1899) p450 PF00067.22 CRK29852.1 - 2.1e-39 135.5 0.0 2.2e-38 132.2 0.0 1.9 2 0 0 2 2 2 2 Cytochrome P450 APH PF01636.23 CRK29853.1 - 9.6e-09 35.5 0.0 4.6e-08 33.3 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CRK29853.1 - 0.0049 16.5 0.0 0.0083 15.7 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase VIR_N PF15912.5 CRK29855.1 - 0.48 10.0 2.7 0.56 9.8 2.7 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal Fasciclin PF02469.22 CRK29858.1 - 7.2e-25 87.7 0.0 1.1e-24 87.1 0.0 1.2 1 0 0 1 1 1 1 Fasciclin domain F-box PF00646.33 CRK29858.1 - 1.5e-06 27.9 0.0 3.2e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 CRK29858.1 - 0.00026 20.8 0.1 0.00057 19.7 0.1 1.5 1 0 0 1 1 1 1 F-box-like APH PF01636.23 CRK29860.1 - 4.1e-15 56.3 0.1 6.6e-15 55.7 0.1 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CRK29860.1 - 3.1e-05 23.6 0.0 4.7e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 CRK29860.1 - 0.057 12.7 0.0 0.083 12.2 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase DUF1679 PF07914.11 CRK29860.1 - 0.091 11.6 0.0 0.16 10.8 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1679) Pkinase PF00069.25 CRK29860.1 - 0.15 11.4 0.0 0.69 9.2 0.0 1.8 2 0 0 2 2 2 0 Protein kinase domain Methyltransf_16 PF10294.9 CRK29881.1 - 1e-09 38.4 0.0 1.7e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase zf-C2H2 PF00096.26 CRK29881.1 - 3.5e-05 24.0 19.0 0.27 11.8 1.2 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CRK29881.1 - 0.096 13.6 20.0 0.48 11.4 0.7 4.8 4 1 0 4 4 4 0 C2H2-type zinc finger zf-TAZ PF02135.16 CRK29881.1 - 0.32 11.5 4.6 0.29 11.6 1.6 2.1 2 0 0 2 2 2 0 TAZ zinc finger Vps39_2 PF10367.9 CRK29882.1 - 1.8e-06 28.4 0.0 3.7e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 GMC_oxred_N PF00732.19 CRK29883.1 - 1.6e-06 27.7 0.1 2.8e-06 26.9 0.0 1.3 2 0 0 2 2 2 1 GMC oxidoreductase C166 PF17615.2 CRK29884.1 - 2.2e-09 37.7 2.4 2.7e-09 37.4 2.4 1.1 1 0 0 1 1 1 1 Family of unknown function HsbA PF12296.8 CRK29884.1 - 8.7e-05 22.9 0.0 0.00023 21.6 0.0 1.7 1 1 0 1 1 1 1 Hydrophobic surface binding protein A Oxidored_molyb PF00174.19 CRK29885.1 - 2.6e-53 180.2 0.0 5e-53 179.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 CRK29885.1 - 2e-36 125.0 0.4 5.2e-36 123.7 0.4 1.7 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain NAD_binding_1 PF00175.21 CRK29885.1 - 5.2e-26 91.4 0.0 2.6e-25 89.2 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 CRK29885.1 - 6.8e-20 71.3 0.0 1.8e-08 34.6 0.0 2.6 2 0 0 2 2 2 2 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.28 CRK29885.1 - 3e-15 56.1 0.1 7.6e-15 54.8 0.1 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 CRK29885.1 - 0.06 13.5 0.0 1.9 8.6 0.0 2.4 2 0 0 2 2 2 0 Ferric reductase NAD binding domain OPT PF03169.15 CRK29886.1 - 0.012 14.3 0.0 0.014 14.1 0.0 1.0 1 0 0 1 1 1 0 OPT oligopeptide transporter protein Barstar PF01337.18 CRK29886.1 - 0.035 14.1 0.2 0.057 13.5 0.2 1.3 1 0 0 1 1 1 0 Barstar (barnase inhibitor) TMEM135_C_rich PF15982.5 CRK29886.1 - 0.04 14.5 0.1 0.047 14.3 0.1 1.1 1 0 0 1 1 1 0 N-terminal cysteine-rich region of Transmembrane protein 135 Histidinol_dh PF00815.20 CRK29887.1 - 1.2e-103 347.3 1.2 7.6e-79 265.6 1.1 2.0 2 0 0 2 2 2 2 Histidinol dehydrogenase Fungal_trans_2 PF11951.8 CRK29888.1 - 2.8e-25 89.0 0.1 3.4e-25 88.7 0.1 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Reovirus_Mu2 PF07781.11 CRK29889.1 - 0.04 12.3 0.0 0.045 12.1 0.0 1.1 1 0 0 1 1 1 0 Reovirus minor core protein Mu-2 NmrA PF05368.13 CRK29892.1 - 1.7e-05 24.5 0.0 2.2e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family MFS_1 PF07690.16 CRK29893.1 - 2e-18 66.5 17.1 2e-18 66.5 17.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF5455 PF17537.2 CRK29893.1 - 0.0029 18.0 1.1 0.29 11.5 0.0 3.0 3 0 0 3 3 3 1 Family of unknown function (DUF5455) DUF2244 PF10003.9 CRK29893.1 - 0.2 11.3 4.0 0.054 13.2 0.6 1.7 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) DUF981 PF06168.11 CRK29893.1 - 0.23 11.3 8.8 3.7 7.4 0.5 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF981) PfkB PF00294.24 CRK29894.1 - 6.1e-68 229.3 0.1 6.9e-68 229.2 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 CRK29894.1 - 0.0034 16.8 0.0 0.0058 16.0 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase EST1_DNA_bind PF10373.9 CRK29896.1 - 1.5e-66 224.8 0.0 2.2e-66 224.2 0.0 1.3 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.9 CRK29896.1 - 6.3e-20 72.2 0.2 1.5e-19 71.0 0.2 1.7 1 0 0 1 1 1 1 Telomerase activating protein Est1 Inositol_P PF00459.25 CRK29897.1 - 5.2e-10 39.3 0.0 6.9e-10 38.9 0.0 1.2 1 1 0 1 1 1 1 Inositol monophosphatase family Epimerase PF01370.21 CRK29898.1 - 6.1e-26 91.4 0.1 2.9e-25 89.2 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CRK29898.1 - 6.3e-20 71.8 0.2 3.1e-14 53.1 0.1 3.0 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 CRK29898.1 - 1.4e-09 37.4 0.0 2e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 CRK29898.1 - 2.3e-09 36.8 0.4 4.9e-06 25.9 0.0 2.9 2 1 1 3 3 3 2 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 CRK29898.1 - 8.8e-09 34.9 0.0 6.7e-08 32.0 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.19 CRK29898.1 - 3.9e-05 22.8 0.0 0.0002 20.5 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 CRK29898.1 - 0.0017 18.3 2.8 0.47 10.3 0.0 2.5 2 1 1 3 3 3 2 KR domain FSH1 PF03959.13 CRK29899.1 - 3.7e-28 98.7 0.0 5.9e-28 98.0 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 CRK29899.1 - 0.21 11.4 0.4 3.3 7.4 0.3 2.6 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase FAD_binding_4 PF01565.23 CRK29900.1 - 0.0048 16.6 0.0 0.0064 16.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain GTP_cyclohydro2 PF00925.20 CRK29901.1 - 1e-59 200.8 0.0 1.9e-59 199.9 0.0 1.4 1 0 0 1 1 1 1 GTP cyclohydrolase II DUF1651 PF07864.11 CRK29901.1 - 0.35 11.2 1.4 0.64 10.4 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1651) SCAB_CC PF16712.5 CRK29902.1 - 0.044 13.6 8.0 0.069 13.0 8.0 1.3 1 0 0 1 1 1 0 Coiled-coil regions of plant-specific actin-binding protein VIR_N PF15912.5 CRK29902.1 - 0.23 11.0 6.7 0.29 10.7 6.7 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal OmpH PF03938.14 CRK29902.1 - 0.24 11.8 16.4 0.26 11.6 15.6 1.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) CCDC50_N PF15295.6 CRK29902.1 - 0.32 11.1 17.6 0.49 10.6 17.6 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus DUF1501 PF07394.12 CRK29902.1 - 0.56 9.2 4.5 0.65 9.0 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) LMBR1 PF04791.16 CRK29902.1 - 0.8 8.5 1.3 0.88 8.4 1.3 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4407 PF14362.6 CRK29902.1 - 6.5 6.0 8.6 9.5 5.5 8.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DDRGK PF09756.9 CRK29902.1 - 8 6.0 21.4 11 5.5 21.4 1.1 1 0 0 1 1 1 0 DDRGK domain Pyr_redox_2 PF07992.14 CRK29903.1 - 3.6e-14 52.7 0.0 4.6e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AA_permease PF00324.21 CRK29904.1 - 1.7e-32 112.7 14.5 1.9e-32 112.5 14.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CRK29904.1 - 3.3e-08 32.8 13.8 3.5e-08 32.7 13.8 1.0 1 0 0 1 1 1 1 Amino acid permease Alpha-amylase PF00128.24 CRK29905.1 - 6.9e-114 380.9 0.1 1.1e-113 380.2 0.1 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 CRK29905.1 - 1.1e-07 31.9 0.0 2.2e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 CRK29905.1 - 0.0046 16.1 0.0 0.0076 15.4 0.0 1.3 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain DUF3459 PF11941.8 CRK29905.1 - 0.014 15.7 0.0 0.056 13.8 0.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF3459) Glyco_hydro_114 PF03537.13 CRK29905.1 - 0.048 13.0 0.5 2.3 7.5 0.0 2.7 2 1 0 2 2 2 0 Glycoside-hydrolase family GH114 Alpha-amylase_C PF02806.18 CRK29905.1 - 0.083 13.4 0.0 0.22 12.0 0.0 1.8 1 0 0 1 1 1 0 Alpha amylase, C-terminal all-beta domain RTC4 PF14474.6 CRK29906.1 - 7.3e-33 113.3 0.0 1.2e-32 112.6 0.0 1.4 1 0 0 1 1 1 1 RTC4-like domain Dynamitin PF04912.14 CRK29907.1 - 4.4e-105 352.2 0.5 6.2e-105 351.7 0.5 1.2 1 0 0 1 1 1 1 Dynamitin ThiS PF02597.20 CRK29907.1 - 5.2e-09 36.6 0.1 3.6e-08 33.9 0.0 2.5 3 1 0 3 3 2 1 ThiS family AIP3 PF03915.13 CRK29907.1 - 0.0022 17.1 0.1 0.026 13.6 0.0 2.1 2 0 0 2 2 2 1 Actin interacting protein 3 Corazonin PF17308.2 CRK29907.1 - 0.0025 18.2 0.1 0.0071 16.7 0.1 1.7 1 0 0 1 1 1 1 Pro-corazonin SKA2 PF16740.5 CRK29907.1 - 0.011 15.5 3.8 1.1 9.1 0.0 3.4 3 1 0 3 3 3 0 Spindle and kinetochore-associated protein 2 Laminin_II PF06009.12 CRK29907.1 - 0.032 14.2 0.2 0.032 14.2 0.2 4.0 4 1 1 5 5 4 0 Laminin Domain II Spore_III_AB PF09548.10 CRK29907.1 - 0.038 14.1 2.0 0.087 12.9 0.2 2.5 3 1 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) ATF7IP_BD PF16788.5 CRK29907.1 - 0.069 13.2 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 ATF-interacting protein binding domain KxDL PF10241.9 CRK29907.1 - 0.18 12.1 2.8 11 6.3 0.1 3.2 3 0 0 3 3 3 0 Uncharacterized conserved protein FH2 PF02181.23 CRK29907.1 - 0.18 10.9 1.5 2.5 7.1 0.0 2.7 3 0 0 3 3 3 0 Formin Homology 2 Domain GrpE PF01025.19 CRK29907.1 - 0.19 11.4 3.7 1.3 8.7 0.7 3.0 3 0 0 3 3 3 0 GrpE Baculo_PEP_C PF04513.12 CRK29907.1 - 0.2 11.7 2.1 2.8 8.0 0.2 3.0 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cytochrom_B562 PF07361.11 CRK29907.1 - 0.23 12.1 7.6 6.5 7.5 0.1 3.3 3 0 0 3 3 3 0 Cytochrome b562 ZapB PF06005.12 CRK29907.1 - 0.29 11.6 10.6 2.9 8.4 1.2 3.8 4 0 0 4 4 4 0 Cell division protein ZapB DUF2894 PF11445.8 CRK29907.1 - 0.32 11.5 12.3 1.5 9.3 2.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) zf-C4H2 PF10146.9 CRK29907.1 - 0.47 10.7 3.1 1.8 8.8 0.7 2.5 3 0 0 3 3 3 0 Zinc finger-containing protein DUF2203 PF09969.9 CRK29907.1 - 0.74 10.5 10.3 20 5.9 0.1 3.4 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) DUF724 PF05266.14 CRK29907.1 - 0.79 9.5 9.9 1.8 8.3 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF724) DUF305 PF03713.13 CRK29907.1 - 0.9 9.7 7.5 0.19 11.9 0.3 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF305) SOGA PF11365.8 CRK29907.1 - 1.1 10.4 4.8 21 6.3 0.0 2.9 3 0 0 3 3 2 0 Protein SOGA AAA_13 PF13166.6 CRK29907.1 - 1.2 7.7 7.6 0.072 11.7 0.6 2.1 2 1 0 3 3 3 0 AAA domain DUF1192 PF06698.11 CRK29907.1 - 1.3 9.1 16.1 0.7 10.0 4.0 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF1192) DUF4407 PF14362.6 CRK29907.1 - 1.4 8.2 14.2 0.88 8.9 2.4 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) DHR10 PF18595.1 CRK29907.1 - 2.2 8.3 17.2 5.9 7.0 0.1 3.7 3 1 0 3 3 3 0 Designed helical repeat protein 10 domain MIP-T3_C PF17749.1 CRK29907.1 - 2.5 8.1 9.3 0.23 11.4 0.8 3.2 4 0 0 4 4 4 0 Microtubule-binding protein MIP-T3 C-terminal region Phage_GP20 PF06810.11 CRK29907.1 - 4 7.2 10.2 0.37 10.6 2.3 2.7 3 0 0 3 3 3 0 Phage minor structural protein GP20 DUF3450 PF11932.8 CRK29907.1 - 5.4 6.3 16.6 1.9 7.7 1.5 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) FlgN PF05130.12 CRK29907.1 - 5.5 7.5 14.8 0.58 10.7 2.5 2.9 2 1 1 3 3 3 0 FlgN protein DivIC PF04977.15 CRK29907.1 - 7.4 6.4 14.7 1.3 8.8 0.3 4.2 4 0 0 4 4 4 0 Septum formation initiator DASH_Spc19 PF08287.11 CRK29907.1 - 9.3 6.1 9.9 0.51 10.2 1.3 2.4 2 1 0 2 2 2 0 Spc19 Prefoldin_2 PF01920.20 CRK29907.1 - 9.3 6.3 10.1 1.3 9.0 0.2 3.5 3 1 0 3 3 3 0 Prefoldin subunit Sugar_tr PF00083.24 CRK29909.1 - 1.8e-82 277.6 18.5 2.2e-82 277.3 18.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK29909.1 - 3.3e-28 98.6 15.3 3.3e-28 98.6 15.3 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 CRK29909.1 - 5.9e-06 25.0 0.7 5.9e-06 25.0 0.7 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Complex1_LYR PF05347.15 CRK29910.1 - 6.5e-15 54.9 1.9 9.7e-15 54.4 1.9 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 CRK29910.1 - 7.6e-07 29.8 0.5 1.2e-06 29.2 0.5 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 CRK29910.1 - 0.031 14.9 0.3 0.09 13.4 0.3 1.7 1 1 0 1 1 1 0 Complex1_LYR-like FAA_hydrolase PF01557.18 CRK29911.1 - 2.2e-61 207.3 0.0 4.2e-61 206.4 0.0 1.4 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family IBR PF01485.21 CRK29911.1 - 3.2e-07 30.5 29.8 0.00021 21.4 11.1 2.9 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain COesterase PF00135.28 CRK29912.1 - 2.1e-80 271.1 0.0 2.4e-80 270.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CRK29912.1 - 0.00056 19.8 0.0 0.0013 18.6 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CRK29912.1 - 0.035 13.6 0.1 0.057 12.9 0.1 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family F-box-like PF12937.7 CRK29913.1 - 0.0001 22.1 0.1 0.00022 21.1 0.1 1.5 1 0 0 1 1 1 1 F-box-like COX17 PF05051.13 CRK29914.1 - 4.9e-21 74.8 6.7 5.6e-21 74.6 6.7 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Mid2 PF04478.12 CRK29916.1 - 0.0028 17.5 0.0 0.0075 16.1 0.0 1.7 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor NCU-G1 PF15065.6 CRK29916.1 - 0.16 10.9 1.2 0.27 10.2 1.2 1.3 1 0 0 1 1 1 0 Lysosomal transcription factor, NCU-G1 SKG6 PF08693.10 CRK29916.1 - 0.17 11.3 3.3 0.43 10.0 3.3 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain ATPgrasp_ST PF14397.6 CRK29917.1 - 0.012 14.8 0.0 0.017 14.4 0.0 1.1 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp HLH PF00010.26 CRK29917.1 - 0.067 13.2 1.4 14 5.7 0.4 2.9 3 0 0 3 3 3 0 Helix-loop-helix DNA-binding domain TAL_FSA PF00923.19 CRK29918.1 - 7e-25 87.9 0.0 3.5e-22 79.1 0.0 2.2 2 0 0 2 2 2 2 Transaldolase/Fructose-6-phosphate aldolase Sugar_tr PF00083.24 CRK29919.1 - 1.2e-80 271.6 22.9 1.7e-80 271.1 22.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK29919.1 - 3.5e-12 45.9 42.3 1.9e-08 33.6 20.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PITH PF06201.13 CRK29920.1 - 1.5e-36 125.9 0.0 2.2e-36 125.3 0.0 1.3 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.20 CRK29920.1 - 1.6e-28 98.7 0.2 2.7e-28 98.0 0.2 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 CRK29920.1 - 3.2e-07 30.8 0.1 6.8e-07 29.7 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 CRK29920.1 - 2.6e-05 24.0 0.0 4.1e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 CRK29920.1 - 9.8e-05 21.8 0.1 0.00016 21.1 0.1 1.3 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 CRK29920.1 - 0.00014 22.1 0.0 0.0012 19.1 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.21 CRK29920.1 - 0.00058 19.8 0.0 0.0025 17.7 0.1 2.0 3 0 0 3 3 3 1 AhpC/TSA family Redoxin PF08534.10 CRK29920.1 - 0.0053 16.5 0.2 0.73 9.5 0.1 2.3 1 1 1 2 2 2 1 Redoxin Thioredoxin_7 PF13899.6 CRK29920.1 - 0.01 16.0 0.2 0.019 15.1 0.2 1.4 1 0 0 1 1 1 0 Thioredoxin-like Phosducin PF02114.16 CRK29920.1 - 0.016 14.2 0.0 0.024 13.6 0.0 1.2 1 0 0 1 1 1 0 Phosducin RhlB PF12300.8 CRK29920.1 - 0.15 12.2 1.9 0.29 11.2 1.9 1.5 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB C166 PF17615.2 CRK29921.1 - 2.3e-28 99.3 9.0 2.9e-28 99.0 9.0 1.1 1 0 0 1 1 1 1 Family of unknown function adh_short PF00106.25 CRK29922.1 - 1.2e-09 37.9 0.1 6.2e-08 32.3 0.0 2.4 2 0 0 2 2 2 1 short chain dehydrogenase Peptidase_S9 PF00326.21 CRK29922.1 - 2.4e-06 27.2 2.6 0.0074 15.8 0.3 3.2 3 0 0 3 3 3 3 Prolyl oligopeptidase family adh_short_C2 PF13561.6 CRK29922.1 - 5.5e-06 26.1 0.1 5.7e-05 22.8 0.1 2.1 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase DLH PF01738.18 CRK29922.1 - 7.1e-05 22.5 0.3 0.1 12.2 0.1 4.0 4 0 0 4 4 4 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 CRK29922.1 - 0.00023 20.9 0.9 0.024 14.3 0.0 2.5 3 0 0 3 3 3 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CRK29922.1 - 0.002 17.4 0.2 0.26 10.5 0.0 2.6 2 1 0 2 2 2 1 Serine aminopeptidase, S33 AXE1 PF05448.12 CRK29922.1 - 0.0028 16.4 0.1 0.0059 15.3 0.1 1.4 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) BAAT_C PF08840.11 CRK29922.1 - 0.2 11.6 0.0 0.42 10.5 0.0 1.5 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal GMC_oxred_N PF00732.19 CRK29923.1 - 1.6e-39 136.1 0.2 3.3e-39 135.0 0.2 1.5 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CRK29923.1 - 5.8e-32 111.2 0.0 1.2e-31 110.2 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 CRK29923.1 - 1.3e-06 27.8 0.9 0.00022 20.4 0.2 2.3 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 CRK29923.1 - 5.6e-06 25.7 0.3 8.3e-06 25.1 0.3 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 CRK29923.1 - 1.3e-05 25.3 0.4 3.4e-05 24.0 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CRK29923.1 - 7.8e-05 22.0 0.4 0.0018 17.6 0.1 2.2 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 CRK29923.1 - 0.00029 20.2 0.0 0.0047 16.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CRK29923.1 - 0.0011 18.7 5.0 0.041 13.5 5.9 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 CRK29923.1 - 0.0024 16.7 0.0 0.0039 16.0 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 CRK29923.1 - 0.011 15.0 0.2 0.077 12.2 0.2 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CRK29923.1 - 0.021 14.1 0.1 0.037 13.3 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.14 CRK29923.1 - 0.022 13.6 0.3 0.035 13.0 0.3 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.6 CRK29923.1 - 0.11 12.5 0.2 0.26 11.3 0.2 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding TrkA_N PF02254.18 CRK29923.1 - 0.15 12.4 0.1 0.33 11.2 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain K_oxygenase PF13434.6 CRK29923.1 - 0.22 10.6 0.0 0.33 10.1 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Abhydrolase_1 PF00561.20 CRK29924.1 - 1.7e-09 37.7 0.0 1.6e-06 28.0 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CRK29924.1 - 0.00025 20.4 0.0 0.29 10.3 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CRK29924.1 - 0.052 14.2 0.0 0.08 13.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DLH PF01738.18 CRK29925.1 - 3.6e-09 36.5 0.1 1.5e-08 34.5 0.1 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 CRK29925.1 - 4.1e-07 29.7 0.1 7.4e-07 28.8 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 CRK29925.1 - 6.9e-06 25.5 0.1 1.1e-05 24.8 0.1 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 AXE1 PF05448.12 CRK29925.1 - 1.3e-05 24.1 0.2 2.6e-05 23.1 0.2 1.4 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.18 CRK29925.1 - 1.5e-05 24.7 0.0 3e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.11 CRK29925.1 - 0.00046 20.2 0.0 0.00079 19.4 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.20 CRK29925.1 - 0.00054 19.7 0.1 0.0011 18.7 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 CRK29925.1 - 0.072 12.9 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Planc_extracel PF07595.12 CRK29925.1 - 5 7.1 9.8 9.5 6.2 0.8 3.1 3 0 0 3 3 3 0 Planctomycete extracellular CHZ PF09649.10 CRK29925.1 - 7.3 6.2 10.9 5.2 6.6 0.3 3.1 3 0 0 3 3 3 0 Histone chaperone domain CHZ adh_short PF00106.25 CRK29926.1 - 3.2e-22 79.0 0.0 4.5e-22 78.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK29926.1 - 3.8e-16 59.4 0.0 4.7e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK29926.1 - 0.00039 20.4 0.0 0.00052 20.0 0.0 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 CRK29926.1 - 0.02 14.3 0.1 0.1 12.0 0.1 2.0 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Ank_2 PF12796.7 CRK29927.1 - 3e-19 69.4 1.9 5.4e-15 55.7 0.3 1.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CRK29927.1 - 2.7e-17 61.1 0.4 8.6e-06 25.7 0.1 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 CRK29927.1 - 8.2e-14 51.8 0.2 3e-09 37.3 0.2 3.2 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 CRK29927.1 - 8.7e-14 51.3 1.8 0.00032 21.0 0.7 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 CRK29927.1 - 2.1e-13 50.2 1.9 3.9e-07 30.2 0.2 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Thymidylate_kin PF02223.17 CRK29927.1 - 0.17 11.5 0.2 0.5 10.0 0.1 1.7 2 0 0 2 2 2 0 Thymidylate kinase bZIP_1 PF00170.21 CRK29927.1 - 0.76 9.9 9.8 1.4 9.0 9.8 1.3 1 0 0 1 1 1 0 bZIP transcription factor MscS_porin PF12795.7 CRK29928.1 - 0.00076 19.1 6.4 0.001 18.7 6.4 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain Pkinase PF00069.25 CRK29928.1 - 0.0011 18.4 0.1 0.0022 17.4 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK29928.1 - 0.017 14.4 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase Spc7 PF08317.11 CRK29928.1 - 0.028 13.3 2.6 0.037 12.9 2.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein ADIP PF11559.8 CRK29928.1 - 0.047 13.8 2.3 0.065 13.3 2.3 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding MBF1 PF08523.10 CRK29928.1 - 0.14 12.7 1.8 0.25 11.8 1.8 1.4 1 0 0 1 1 1 0 Multiprotein bridging factor 1 Hydrolase_4 PF12146.8 CRK29929.1 - 4.1e-08 32.8 0.0 1.5e-07 30.9 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 CRK29929.1 - 7.7e-08 32.1 0.0 1.1e-05 25.0 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family AXE1 PF05448.12 CRK29929.1 - 8e-07 28.0 0.0 2.8e-05 22.9 0.0 2.4 2 1 1 3 3 3 1 Acetyl xylan esterase (AXE1) DLH PF01738.18 CRK29929.1 - 1.4e-05 24.7 0.0 2.2e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 CRK29929.1 - 3.1e-05 24.0 0.0 5e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.18 CRK29929.1 - 7.5e-05 22.4 0.0 0.00015 21.4 0.0 1.4 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) DUF1100 PF06500.11 CRK29929.1 - 0.00015 20.7 0.0 0.0002 20.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_1 PF00561.20 CRK29929.1 - 0.012 15.3 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Zn_clus PF00172.18 CRK29930.1 - 8e-07 29.1 7.5 2.1e-06 27.7 7.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 CRK29931.1 - 7.2e-40 137.0 52.5 2.2e-39 135.4 47.6 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CRK29931.1 - 7.3e-10 37.9 15.2 1e-09 37.4 15.2 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) p450 PF00067.22 CRK29932.1 - 7.7e-40 137.0 0.0 1.1e-39 136.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 CFEM PF05730.11 CRK29934.1 - 6.7e-06 26.1 12.8 9.1e-06 25.7 12.8 1.2 1 0 0 1 1 1 1 CFEM domain DUF832 PF05734.11 CRK29934.1 - 0.037 13.5 3.8 0.043 13.3 3.8 1.1 1 0 0 1 1 1 0 Herpesvirus protein of unknown function (DUF832) CFEM PF05730.11 CRK29935.1 - 8.7e-06 25.7 7.9 1.5e-05 25.0 7.9 1.4 1 0 0 1 1 1 1 CFEM domain TAXi_C PF14541.6 CRK29938.1 - 0.2 11.4 0.0 0.35 10.6 0.0 1.3 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal ATPase_gene1 PF09527.10 CRK29940.1 - 0.036 14.2 0.5 0.072 13.3 0.5 1.5 1 0 0 1 1 1 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter ADH_N PF08240.12 CRK29943.1 - 8.6e-22 77.1 5.4 1.3e-21 76.5 5.4 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CRK29943.1 - 5.7e-20 71.6 0.0 1.1e-19 70.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CRK29943.1 - 9.9e-08 33.1 0.0 1.9e-07 32.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 CRK29943.1 - 0.00048 19.5 0.0 0.00089 18.6 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 CRK29943.1 - 0.0062 15.9 0.4 0.011 15.1 0.4 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF456 PF04306.13 CRK29944.1 - 0.0034 17.7 0.0 0.0044 17.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF456) Gypsy PF07253.11 CRK29944.1 - 0.0064 15.1 0.0 0.0073 14.9 0.0 1.0 1 0 0 1 1 1 1 Gypsy protein Mid2 PF04478.12 CRK29944.1 - 0.057 13.3 0.0 0.07 13.0 0.0 1.1 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF2207 PF09972.9 CRK29944.1 - 0.057 12.2 0.0 0.057 12.2 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Nitrate_red_gam PF02665.14 CRK29944.1 - 0.061 12.9 0.0 0.07 12.7 0.0 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit Protocadherin PF08374.11 CRK29944.1 - 0.067 13.2 0.0 0.074 13.0 0.0 1.1 1 0 0 1 1 1 0 Protocadherin CD34_antigen PF06365.12 CRK29944.1 - 0.068 12.7 0.0 0.081 12.5 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family DUF4448 PF14610.6 CRK29944.1 - 0.12 12.1 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) LapA_dom PF06305.11 CRK29944.1 - 0.14 12.0 0.1 0.43 10.4 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF3761 PF12587.8 CRK29944.1 - 0.16 12.4 0.1 0.6 10.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3761) EphA2_TM PF14575.6 CRK29944.1 - 0.16 12.8 0.0 0.63 11.0 0.0 1.8 1 1 1 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Phage_TTP_12 PF16461.5 CRK29945.1 - 0.029 14.0 0.2 1.6 8.4 0.0 2.5 1 1 1 2 2 2 0 Lambda phage tail tube protein, TTP fn3 PF00041.21 CRK29945.1 - 0.049 14.0 0.2 0.077 13.4 0.2 1.4 1 0 0 1 1 1 0 Fibronectin type III domain GPI-anchored PF10342.9 CRK29945.1 - 0.22 12.3 1.9 0.39 11.5 1.7 1.5 1 1 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family BNR_2 PF13088.6 CRK29946.1 - 0.0054 16.1 0.0 0.017 14.4 0.0 1.8 1 1 0 1 1 1 1 BNR repeat-like domain BNR PF02012.20 CRK29946.1 - 0.0055 16.5 1.4 3.9 7.9 0.4 3.2 2 0 0 2 2 2 2 BNR/Asp-box repeat Sortilin-Vps10 PF15902.5 CRK29946.1 - 0.19 10.5 0.0 18 3.9 0.0 2.8 3 0 0 3 3 3 0 Sortilin, neurotensin receptor 3, Trypsin PF00089.26 CRK29947.1 - 8.4e-65 218.7 1.9 9.6e-65 218.5 1.9 1.0 1 0 0 1 1 1 1 Trypsin Inhibitor_I66 PF16850.5 CRK29948.1 - 4.9e-07 29.7 0.0 6.6e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I66 Peptidase_S41 PF03572.18 CRK29949.1 - 3.6e-05 23.4 0.0 0.00011 21.9 0.0 1.8 1 1 0 1 1 1 1 Peptidase family S41 4HBT PF03061.22 CRK29950.1 - 1.4e-13 51.0 1.2 2.9e-13 50.0 1.2 1.5 1 0 0 1 1 1 1 Thioesterase superfamily CorA PF01544.18 CRK29951.1 - 1.4e-25 90.2 3.3 3.3e-25 89.0 3.3 1.5 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF3177 PF11375.8 CRK29951.1 - 0.024 14.4 1.7 0.044 13.6 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3177) Ricin_B_lectin PF00652.22 CRK29952.1 - 2.1e-09 37.7 0.1 0.00096 19.4 0.0 4.0 2 2 1 3 3 3 3 Ricin-type beta-trefoil lectin domain AA_permease_2 PF13520.6 CRK29953.1 - 1.8e-39 135.8 43.0 1.7e-36 125.9 33.8 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.21 CRK29953.1 - 2.5e-11 42.9 28.0 2.5e-11 42.9 28.0 2.0 1 1 1 2 2 2 2 Amino acid permease Glyco_hydro_18 PF00704.28 CRK29954.1 - 1.6e-63 215.3 0.0 1.8e-63 215.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Lipocalin_9 PF17186.4 CRK29954.1 - 0.028 14.7 0.0 0.059 13.7 0.0 1.6 1 0 0 1 1 1 0 Lipocalin-like domain Polysacc_deac_1 PF01522.21 CRK29955.1 - 5.6e-28 97.3 0.0 9.7e-28 96.6 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 CRK29955.1 - 0.0048 16.1 0.0 0.0084 15.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 Abhydrolase_6 PF12697.7 CRK29956.1 - 1.2e-14 55.5 5.5 2.5e-14 54.4 5.5 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CRK29956.1 - 3.8e-14 52.5 0.0 1.7e-11 43.9 0.0 2.9 3 0 0 3 3 3 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CRK29956.1 - 6.1e-13 49.0 0.0 1.6e-12 47.6 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold DSPc PF00782.20 CRK29956.1 - 3.4e-09 36.6 0.0 6.2e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Thioesterase PF00975.20 CRK29956.1 - 4.2e-06 27.1 0.1 1.3e-05 25.5 0.0 1.8 2 0 0 2 2 2 1 Thioesterase domain PTPlike_phytase PF14566.6 CRK29956.1 - 0.00043 20.4 0.0 0.00085 19.5 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate CENP-B_dimeris PF09026.10 CRK29956.1 - 0.018 15.4 6.0 0.018 15.4 6.0 2.0 3 0 0 3 3 1 0 Centromere protein B dimerisation domain LIDHydrolase PF10230.9 CRK29956.1 - 0.085 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase FSH1 PF03959.13 CRK29956.1 - 0.094 12.4 0.0 10 5.7 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Y_phosphatase PF00102.27 CRK29956.1 - 0.14 11.7 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Lipase_3 PF01764.25 CRK29956.1 - 0.16 11.8 0.1 0.49 10.2 0.0 1.6 1 1 0 2 2 2 0 Lipase (class 3) Abhydrolase_2 PF02230.16 CRK29956.1 - 0.16 11.8 0.0 5.3 6.8 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DNA_pol_phi PF04931.13 CRK29956.1 - 4.6 5.2 9.6 7.3 4.6 9.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi DUF498 PF04430.14 CRK29957.1 - 1.9e-25 89.0 0.0 2.7e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Ribosomal_L34e PF01199.18 CRK29959.1 - 6.1e-17 61.7 0.4 1.2e-16 60.8 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L34e Ribosomal_L34e PF01199.18 CRK29960.1 - 1.7e-43 146.8 3.7 2.3e-43 146.4 3.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e FhuF_C PF11575.8 CRK29960.1 - 0.36 10.8 4.4 1.7 8.7 0.3 2.5 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain Spore_III_AB PF09548.10 CRK29961.1 - 0.22 11.6 0.4 0.27 11.3 0.4 1.1 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) FAR1 PF03101.15 CRK29962.1 - 4.6e-06 27.2 0.3 7.5e-06 26.6 0.3 1.3 1 0 0 1 1 1 1 FAR1 DNA-binding domain Matrilin_ccoil PF10393.9 CRK29962.1 - 0.0076 16.1 0.4 0.017 15.0 0.1 1.8 2 0 0 2 2 2 1 Trimeric coiled-coil oligomerisation domain of matrilin Sec3_C PF09763.9 CRK29962.1 - 0.016 13.7 0.1 0.021 13.2 0.1 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 XhlA PF10779.9 CRK29962.1 - 0.016 15.4 0.1 0.04 14.1 0.0 1.6 2 0 0 2 2 2 0 Haemolysin XhlA AFT PF08731.11 CRK29962.1 - 0.021 15.2 0.2 0.033 14.6 0.2 1.3 1 0 0 1 1 1 0 Transcription factor AFT HSBP1 PF06825.12 CRK29962.1 - 0.052 13.4 2.1 0.24 11.3 0.6 2.5 1 1 1 2 2 2 0 Heat shock factor binding protein 1 Baculo_PEP_C PF04513.12 CRK29962.1 - 0.052 13.6 0.0 0.082 13.0 0.0 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Snapin_Pallidin PF14712.6 CRK29962.1 - 0.056 13.9 0.1 0.11 13.0 0.1 1.5 1 0 0 1 1 1 0 Snapin/Pallidin Hemagglutinin PF00509.18 CRK29962.1 - 0.058 11.8 0.0 0.078 11.4 0.0 1.1 1 0 0 1 1 1 0 Haemagglutinin DUF1664 PF07889.12 CRK29962.1 - 0.061 13.4 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) CLZ PF16526.5 CRK29962.1 - 0.081 13.3 0.4 0.25 11.7 0.4 1.9 1 1 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF948 PF06103.11 CRK29962.1 - 0.094 13.0 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) CCDC154 PF15450.6 CRK29962.1 - 0.18 10.3 0.0 0.23 10.0 0.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 154 Alk_phosphatase PF00245.20 CRK29963.1 - 2.4e-106 356.2 0.0 2.8e-106 356.0 0.0 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 CRK29963.1 - 1.4e-05 24.6 0.1 2.7e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily SBP_bac_1 PF01547.25 CRK29964.1 - 0.032 14.2 0.0 0.043 13.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.6 CRK29964.1 - 0.037 13.8 0.0 0.055 13.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 CRK29964.1 - 0.13 12.1 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein OPT PF03169.15 CRK29965.1 - 5.7e-80 269.7 21.8 2.1e-56 191.8 16.3 2.0 1 1 1 2 2 2 2 OPT oligopeptide transporter protein Arylsulfotran_2 PF14269.6 CRK29966.1 - 2.6e-65 220.7 0.0 4.5e-65 220.0 0.0 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 CRK29966.1 - 1.1e-17 64.0 0.1 1.4e-16 60.4 0.1 2.1 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Fungal_trans PF04082.18 CRK29967.1 - 2.4e-14 53.0 0.2 5e-14 52.0 0.2 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Rad9 PF04139.13 CRK29968.1 - 1.2e-41 142.8 0.0 1.5e-41 142.5 0.0 1.1 1 0 0 1 1 1 1 Rad9 PDH PF02153.17 CRK29969.1 - 3e-16 59.2 0.0 4.3e-16 58.7 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.15 CRK29969.1 - 1.8e-07 31.5 0.0 3.6e-07 30.5 0.0 1.6 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 CRK29969.1 - 8.5e-07 29.5 0.0 1.7e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 CRK29969.1 - 8.6e-05 22.0 0.0 0.00016 21.1 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 CRK29969.1 - 0.00064 19.4 0.0 0.0013 18.4 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 CRK29969.1 - 0.0083 16.4 0.0 0.018 15.3 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain Shikimate_DH PF01488.20 CRK29969.1 - 0.026 14.6 0.0 0.057 13.5 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 CRK29969.1 - 0.057 13.3 0.1 0.098 12.5 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Mpv17_PMP22 PF04117.12 CRK29971.1 - 1.4e-10 41.3 3.2 6.4e-10 39.1 3.3 2.0 2 0 0 2 2 2 1 Mpv17 / PMP22 family EAP30 PF04157.16 CRK29972.1 - 2.7e-17 62.8 0.0 3.2e-17 62.6 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Ribosomal_S9 PF00380.19 CRK29973.1 - 7.6e-34 116.8 0.2 8.7e-34 116.7 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ank_2 PF12796.7 CRK29977.1 - 9.7e-09 35.7 0.5 3.8e-07 30.6 0.1 3.1 3 1 0 3 3 3 1 Ankyrin repeats (3 copies) Ank PF00023.30 CRK29977.1 - 7.5e-08 32.5 2.9 4.8e-05 23.6 0.1 4.1 4 0 0 4 4 4 1 Ankyrin repeat Ank_3 PF13606.6 CRK29977.1 - 5.2e-06 26.4 0.4 0.25 12.0 0.0 4.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 CRK29977.1 - 0.00013 22.4 1.7 0.0072 16.9 0.0 3.6 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 CRK29977.1 - 0.0002 21.6 0.5 0.0052 17.1 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeats (many copies) zf-C2H2_4 PF13894.6 CRK29977.1 - 3.1 8.9 5.4 58 4.9 0.3 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger TAF4 PF05236.14 CRK29981.1 - 0.008 16.0 0.4 0.0093 15.7 0.4 1.1 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family zf-C2H2 PF00096.26 CRK29981.1 - 0.1 13.1 0.2 0.2 12.2 0.2 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type FOXP-CC PF16159.5 CRK29981.1 - 0.11 13.1 0.4 0.18 12.4 0.4 1.3 1 0 0 1 1 1 0 FOXP coiled-coil domain Env-gp36 PF09590.10 CRK29981.1 - 0.22 9.9 0.7 0.28 9.5 0.7 1.0 1 0 0 1 1 1 0 Lentivirus surface glycoprotein YabA PF06156.13 CRK29981.1 - 1.4 9.6 5.6 1.5 9.5 0.2 2.1 1 1 1 2 2 2 0 Initiation control protein YabA Fungal_trans PF04082.18 CRK29983.1 - 2.3e-09 36.7 1.4 5.1e-09 35.5 0.1 2.1 2 1 1 3 3 3 1 Fungal specific transcription factor domain ABC_membrane PF00664.23 CRK29986.1 - 5.2e-82 275.6 34.4 7.6e-42 143.8 14.2 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CRK29986.1 - 1.9e-64 216.3 0.0 1.1e-34 119.8 0.0 2.3 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CRK29986.1 - 1e-11 44.7 0.6 0.00035 20.1 0.1 4.0 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CRK29986.1 - 8.8e-09 35.0 0.4 0.0015 18.2 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 CRK29986.1 - 9.3e-08 32.4 0.2 0.026 14.8 0.1 3.7 2 2 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 CRK29986.1 - 1.6e-07 31.4 0.0 0.026 14.5 0.0 2.7 3 0 0 3 3 2 2 RsgA GTPase AAA_21 PF13304.6 CRK29986.1 - 2.3e-07 31.0 1.8 0.11 12.2 0.1 4.0 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 CRK29986.1 - 3.1e-07 30.9 2.5 0.0042 17.5 0.3 3.0 2 2 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 CRK29986.1 - 5.3e-06 26.1 0.6 0.14 11.7 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.6 CRK29986.1 - 1.9e-05 25.3 0.3 0.11 13.0 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 CRK29986.1 - 6.2e-05 22.9 0.0 0.16 11.7 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 CRK29986.1 - 0.00011 22.0 2.3 0.18 11.5 0.2 3.6 2 2 0 2 2 2 2 AAA domain ABC_ATPase PF09818.9 CRK29986.1 - 0.00012 21.0 5.5 0.017 13.9 0.0 3.8 5 0 0 5 5 5 2 Predicted ATPase of the ABC class AAA_5 PF07728.14 CRK29986.1 - 0.00071 19.6 0.3 5.1 7.1 0.0 3.7 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA PF00004.29 CRK29986.1 - 0.00077 19.9 1.5 3.9 7.9 0.0 4.2 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 CRK29986.1 - 0.001 19.2 0.0 2.3 8.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 CRK29986.1 - 0.0023 17.5 0.0 1.4 8.4 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_28 PF13521.6 CRK29986.1 - 0.0027 17.9 2.2 0.19 12.0 0.1 3.0 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.6 CRK29986.1 - 0.0036 17.8 0.1 3 8.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 CRK29986.1 - 0.0052 16.1 0.0 3.1 7.0 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin MMR_HSR1 PF01926.23 CRK29986.1 - 0.0057 16.7 0.1 0.85 9.7 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase SbcCD_C PF13558.6 CRK29986.1 - 0.015 15.5 3.9 6.5 7.1 0.6 3.9 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Rad17 PF03215.15 CRK29986.1 - 0.018 15.0 0.0 5.7 6.8 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain NB-ARC PF00931.22 CRK29986.1 - 0.036 13.2 0.3 1.6 7.8 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.22 CRK29986.1 - 0.044 14.2 0.1 6.2 7.3 0.0 2.6 2 0 0 2 2 2 0 RNA helicase SRP54 PF00448.22 CRK29986.1 - 0.074 12.7 0.0 3.6 7.2 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain G-alpha PF00503.20 CRK29986.1 - 0.076 12.2 0.0 8.7 5.4 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit ATP_bind_1 PF03029.17 CRK29986.1 - 0.14 11.9 0.0 8.4 6.1 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein RICTOR_N PF14664.6 CRK29988.1 - 8.5e-127 423.2 0.6 2.9e-126 421.5 0.0 2.3 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, N-term Phos_pyr_kin PF08543.12 CRK29988.1 - 4.2e-72 242.5 1.1 7.8e-72 241.6 1.1 1.4 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 CRK29988.1 - 1.8e-49 168.4 0.0 1.3e-48 165.6 0.0 2.3 2 0 0 2 2 2 1 TENA/THI-4/PQQC family DEAD PF00270.29 CRK29988.1 - 1.1e-48 165.4 0.0 6.1e-48 162.9 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase RICTOR_M PF14666.6 CRK29988.1 - 1.1e-34 118.4 0.3 2.8e-33 113.8 0.0 3.6 4 0 0 4 4 3 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.6 CRK29988.1 - 1.6e-34 118.6 0.2 3.7e-33 114.2 0.0 3.1 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain Helicase_C PF00271.31 CRK29988.1 - 1.1e-31 109.4 0.1 3.6e-31 107.8 0.1 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RICTOR_V PF14668.6 CRK29988.1 - 8.8e-30 102.8 0.6 2.8e-27 94.7 0.1 4.3 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.16 CRK29988.1 - 1.8e-16 60.0 10.6 1.8e-16 60.0 10.6 2.5 2 0 0 2 2 2 1 Hr1 repeat ResIII PF04851.15 CRK29988.1 - 0.00018 21.6 0.0 0.00056 20.0 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PfkB PF00294.24 CRK29988.1 - 0.00054 19.4 0.1 0.004 16.5 0.1 2.2 1 1 0 1 1 1 1 pfkB family carbohydrate kinase HEAT_2 PF13646.6 CRK29988.1 - 0.025 15.0 0.6 4.1 7.9 0.0 3.4 2 0 0 2 2 2 0 HEAT repeats DUF2443 PF10398.9 CRK29988.1 - 0.044 13.8 3.9 4.6 7.4 0.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2443) UTP25 PF06862.12 CRK29988.1 - 0.047 12.5 0.0 1 8.0 0.0 2.2 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Uds1 PF15456.6 CRK29988.1 - 0.14 12.4 11.1 0.47 10.6 11.1 1.9 1 0 0 1 1 1 0 Up-regulated During Septation NA37 PF04245.13 CRK29988.1 - 0.42 10.0 5.8 18 4.7 0.0 3.0 2 0 0 2 2 2 0 37-kD nucleoid-associated bacterial protein CENP-K PF11802.8 CRK29988.1 - 0.68 9.4 7.7 2.2 7.8 7.7 1.8 1 0 0 1 1 1 0 Centromere-associated protein K Arm PF00514.23 CRK29988.1 - 1.1 9.5 3.9 18 5.5 0.0 4.2 5 0 0 5 5 3 0 Armadillo/beta-catenin-like repeat Ribosomal_L13 PF00572.18 CRK29994.1 - 3e-42 143.8 0.0 4.2e-42 143.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Sod_Cu PF00080.20 CRK29996.1 - 1.1e-11 45.1 0.0 1.8e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) HMA PF00403.26 CRK29996.1 - 4.1e-09 36.8 0.1 6.3e-09 36.2 0.1 1.4 1 0 0 1 1 1 1 Heavy-metal-associated domain NIF3 PF01784.18 CRK29996.1 - 0.047 13.3 0.0 0.066 12.8 0.0 1.2 1 0 0 1 1 1 0 NIF3 (NGG1p interacting factor 3) HMA PF00403.26 CRK29998.1 - 1.4e-09 38.2 0.1 2.1e-09 37.7 0.1 1.3 1 0 0 1 1 1 1 Heavy-metal-associated domain RusA PF05866.11 CRK29998.1 - 0.043 14.3 0.3 1.1 9.8 0.0 2.0 1 1 1 2 2 2 0 Endodeoxyribonuclease RusA TPR_1 PF00515.28 CRK29999.1 - 2e-10 40.1 0.0 1.4e-08 34.2 0.0 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 CRK29999.1 - 1.4e-08 34.2 0.2 1.7e-06 27.7 0.0 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 CRK29999.1 - 2.3e-07 30.4 0.1 3.2e-06 26.8 0.0 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 CRK29999.1 - 1.8e-06 27.7 0.1 5.9e-06 26.1 0.0 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 CRK29999.1 - 3e-06 26.8 0.0 1e-05 25.1 0.0 2.0 1 0 0 1 1 1 1 TPR repeat PB1 PF00564.24 CRK29999.1 - 2.9e-05 23.9 0.1 4.9e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 PB1 domain TPR_12 PF13424.6 CRK29999.1 - 0.00017 21.8 0.0 0.00056 20.2 0.0 1.8 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 CRK29999.1 - 0.00021 21.1 0.0 0.15 12.0 0.0 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 CRK29999.1 - 0.0059 17.2 0.0 0.074 13.7 0.0 2.7 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 CRK29999.1 - 0.026 14.9 0.0 5.6 7.6 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 CRK29999.1 - 0.033 15.0 0.0 0.13 13.1 0.0 2.0 2 0 0 2 2 1 0 Tetratricopeptide repeat tRNA-synt_1c PF00749.21 CRK30000.1 - 3.1e-92 308.8 0.0 4.4e-92 308.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain DnaJ_C PF01556.18 CRK30001.1 - 1.4e-35 122.6 0.2 2e-35 122.0 0.2 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CRK30001.1 - 3.2e-23 81.6 1.7 6.6e-23 80.6 1.7 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CRK30001.1 - 2e-14 53.7 18.7 3.4e-14 53.0 18.7 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 CRK30001.1 - 0.0043 17.0 12.1 0.16 12.0 1.7 2.6 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 CRK30001.1 - 0.067 13.2 7.7 0.9 9.6 1.6 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 CRK30001.1 - 0.67 10.0 9.9 4.1 7.5 1.6 2.4 2 0 0 2 2 2 0 Double zinc ribbon TackOD1 PF18551.1 CRK30001.1 - 2.2 7.9 8.4 5 6.8 1.9 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 PolC_DP2 PF03833.13 CRK30001.1 - 2.3 6.0 5.8 3.5 5.4 5.8 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-RING_10 PF16685.5 CRK30001.1 - 2.4 8.3 11.3 0.42 10.8 2.1 2.3 1 1 1 2 2 2 0 zinc RING finger of MSL2 DUF1356 PF07092.12 CRK30001.1 - 2.7 7.2 4.8 2.1 7.6 0.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1356) Ribosomal_L32e PF01655.18 CRK30002.1 - 6.3e-50 168.1 0.3 6.3e-50 168.1 0.3 1.4 2 0 0 2 2 2 1 Ribosomal protein L32 Peptidase_S41 PF03572.18 CRK30005.1 - 0.044 13.3 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 Peptidase family S41 ELFV_dehydrog PF00208.21 CRK30009.1 - 6e-66 222.6 0.0 9.9e-66 221.9 0.0 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 CRK30009.1 - 7.7e-19 66.8 0.0 1.5e-13 49.3 0.0 2.2 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 CRK30009.1 - 0.0042 17.0 0.0 0.037 13.9 0.0 2.2 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Abhydrolase_2 PF02230.16 CRK30011.1 - 7.5e-23 81.5 0.0 2.2e-22 80.0 0.0 1.7 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 CRK30011.1 - 6.6e-06 26.1 0.2 0.046 13.6 0.2 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CRK30011.1 - 1.5e-05 25.7 5.2 0.00085 20.0 1.4 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 CRK30011.1 - 0.001 18.6 0.1 0.0042 16.6 0.0 2.0 3 0 0 3 3 3 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 CRK30011.1 - 0.051 12.8 0.1 17 4.6 0.0 2.9 3 0 0 3 3 3 0 Serine aminopeptidase, S33 FSH1 PF03959.13 CRK30011.1 - 0.062 13.0 0.0 0.45 10.1 0.0 2.2 1 1 0 1 1 1 0 Serine hydrolase (FSH1) CBM_1 PF00734.18 CRK30012.1 - 3.2e-23 81.4 23.1 8.7e-13 48.0 9.1 2.4 2 0 0 2 2 2 2 Fungal cellulose binding domain Toxin_7 PF05980.12 CRK30012.1 - 0.13 12.5 3.0 0.77 10.1 0.4 2.4 2 0 0 2 2 2 0 Toxin 7 zf-CCHC_6 PF15288.6 CRK30012.1 - 0.48 10.3 11.2 1.6 8.7 4.3 2.8 2 0 0 2 2 2 0 Zinc knuckle Peptidase_S8 PF00082.22 CRK30013.1 - 9e-21 74.4 6.2 1.3e-20 73.8 6.2 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 CRK30013.1 - 1.2e-11 45.1 0.0 1.9e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase inhibitor I9 BBE PF08031.12 CRK30014.1 - 0.12 12.5 0.0 0.32 11.1 0.0 1.7 1 0 0 1 1 1 0 Berberine and berberine like MutS_V PF00488.21 CRK30018.1 - 2.3e-65 220.1 0.0 5.9e-65 218.8 0.0 1.7 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 CRK30018.1 - 2.5e-32 112.7 1.0 5.1e-32 111.6 1.0 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 CRK30018.1 - 1.5e-29 102.5 0.0 3e-29 101.6 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 CRK30018.1 - 2.6e-10 40.7 0.0 1.1e-09 38.7 0.0 2.1 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 CRK30018.1 - 0.00035 20.9 0.0 0.00089 19.6 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV DUF4911 PF16256.5 CRK30018.1 - 0.08 12.9 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4911) zf-C2H2_2 PF12756.7 CRK30019.1 - 0.058 13.7 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Peptidase_M28 PF04389.17 CRK30020.1 - 4.1e-30 104.9 0.1 5.7e-30 104.5 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 CRK30020.1 - 5.8e-13 48.7 0.1 1.2e-12 47.6 0.1 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 CRK30020.1 - 0.00014 21.6 0.1 0.00028 20.6 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 RhoGAP PF00620.27 CRK30022.1 - 1.8e-28 99.3 0.0 3.4e-28 98.4 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain SCIMP PF15050.6 CRK30022.1 - 9.6 6.7 5.8 3.2 8.2 1.4 2.5 2 0 0 2 2 2 0 SCIMP protein RRS1 PF04939.12 CRK30023.1 - 1.6e-23 83.4 4.0 4e-23 82.1 4.0 1.6 1 1 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) DAP3 PF10236.9 CRK30024.1 - 1.7e-92 310.0 0.0 2e-92 309.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 CRK30024.1 - 0.001 19.5 0.0 0.0034 17.8 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain MCM PF00493.23 CRK30025.1 - 1.5e-83 279.3 0.2 2.2e-83 278.8 0.2 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CRK30025.1 - 5.7e-30 103.8 1.0 9.8e-30 103.0 1.0 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_N PF14551.6 CRK30025.1 - 1.9e-16 60.5 0.8 4.4e-16 59.3 0.8 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 CRK30025.1 - 1.6e-07 30.9 0.0 2.2e-05 23.9 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CRK30025.1 - 1.9e-05 24.7 0.0 7.7e-05 22.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 CRK30025.1 - 0.068 12.9 0.1 0.67 9.6 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_3 PF07726.11 CRK30025.1 - 0.071 13.0 0.0 0.24 11.3 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ribosomal_L2_C PF03947.18 CRK30026.1 - 1.1e-42 145.2 3.6 1.9e-42 144.5 3.6 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain DUF1770 PF08589.10 CRK30026.1 - 2.1e-36 124.8 0.5 3.2e-36 124.3 0.5 1.3 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) Ribosomal_L2 PF00181.23 CRK30026.1 - 8.8e-13 48.0 0.0 2.1e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain DUF3139 PF11337.8 CRK30026.1 - 0.077 13.7 0.1 0.16 12.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) ATG101 PF07855.12 CRK30027.1 - 5.3e-37 127.2 0.1 1.1e-36 126.1 0.0 1.5 2 0 0 2 2 2 1 Autophagy-related protein 101 Herpes_UL25 PF01499.16 CRK30028.1 - 0.00064 18.4 1.1 0.00075 18.1 1.1 1.1 1 0 0 1 1 1 1 Herpesvirus UL25 family YscO PF07321.12 CRK30028.1 - 0.01 15.8 6.8 0.01 15.8 6.8 1.6 2 0 0 2 2 2 0 Type III secretion protein YscO DUF2852 PF11014.8 CRK30028.1 - 0.029 14.5 1.2 0.05 13.8 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) SAT PF16073.5 CRK30028.1 - 0.059 13.1 0.0 0.079 12.7 0.0 1.3 1 0 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis bZIP_2 PF07716.15 CRK30028.1 - 0.098 12.8 1.0 0.098 12.8 1.0 3.4 2 1 2 4 4 4 0 Basic region leucine zipper ZapB PF06005.12 CRK30028.1 - 0.53 10.8 7.9 0.087 13.3 3.9 1.8 2 0 0 2 2 2 0 Cell division protein ZapB Metal_resist PF13801.6 CRK30028.1 - 3 8.1 13.5 0.12 12.6 6.5 1.9 2 0 0 2 2 2 0 Heavy-metal resistance E1-E2_ATPase PF00122.20 CRK30030.1 - 1.2e-49 168.4 5.1 1.2e-49 168.4 5.1 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 CRK30030.1 - 4.1e-17 63.2 0.7 1.4e-16 61.4 0.1 2.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CRK30030.1 - 1.9e-09 37.1 0.0 4.4e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CRK30030.1 - 0.0023 17.7 0.1 0.0048 16.7 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CRK30030.1 - 0.013 15.5 0.0 0.03 14.4 0.0 1.5 1 0 0 1 1 1 0 Cation transport ATPase (P-type) DUF2613 PF11021.8 CRK30030.1 - 3 8.0 9.1 4.8 7.4 0.8 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) Ras PF00071.22 CRK30032.1 - 2.1e-34 118.5 0.0 2.5e-34 118.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CRK30032.1 - 1.1e-12 48.2 0.0 1.7e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CRK30032.1 - 1.1e-05 24.9 0.0 1.4e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CRK30032.1 - 0.0067 16.0 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Glyco_hydro_75 PF07335.11 CRK30032.1 - 0.091 13.0 0.0 0.1 12.9 0.0 1.2 1 0 0 1 1 1 0 Fungal chitosanase of glycosyl hydrolase group 75 EamA PF00892.20 CRK30033.1 - 7.9e-10 39.0 15.5 2.2e-08 34.4 2.5 3.1 3 0 0 3 3 3 2 EamA-like transporter family DUF3955 PF13127.6 CRK30033.1 - 4.1e-09 36.1 0.2 4.1e-09 36.1 0.2 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF3955) SLC35F PF06027.12 CRK30033.1 - 1e-07 31.8 2.8 1e-07 31.8 2.8 1.6 2 0 0 2 2 2 1 Solute carrier family 35 PUNUT PF16913.5 CRK30033.1 - 0.00017 20.9 1.4 0.00017 20.9 1.4 1.5 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport CRT-like PF08627.10 CRK30033.1 - 0.024 13.6 1.1 0.037 13.0 0.3 1.6 1 1 0 2 2 2 0 CRT-like, chloroquine-resistance transporter-like UAA PF08449.11 CRK30033.1 - 0.037 13.2 4.4 0.013 14.7 1.9 1.4 2 0 0 2 2 2 0 UAA transporter family Stk19 PF10494.9 CRK30034.1 - 4.3e-67 226.4 0.0 5.2e-67 226.1 0.0 1.1 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 F-box-like PF12937.7 CRK30036.1 - 0.00026 20.8 0.1 0.00048 20.0 0.1 1.5 1 0 0 1 1 1 1 F-box-like AhpC-TSA_2 PF13911.6 CRK30038.1 - 0.00013 22.1 0.0 0.00018 21.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 CRK30038.1 - 0.00046 20.1 0.0 0.0006 19.7 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family DUF5441 PF17513.2 CRK30039.1 - 0.08 12.7 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5441) Glyco_hydro_3 PF00933.21 CRK30040.1 - 2.9e-36 125.5 0.0 3.7e-36 125.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Ribosomal_L44 PF00935.19 CRK30042.1 - 1.1e-36 125.1 12.5 1.6e-36 124.6 12.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 MHB PF16525.5 CRK30043.1 - 0.043 14.1 0.0 0.077 13.3 0.0 1.4 1 0 0 1 1 1 0 Haemophore, haem-binding Ribosomal_L44 PF00935.19 CRK30044.1 - 1.1e-36 125.1 12.5 1.6e-36 124.6 12.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 CTP_transf_like PF01467.26 CRK30045.1 - 0.0076 16.5 0.1 0.13 12.5 0.1 2.3 2 0 0 2 2 2 1 Cytidylyltransferase-like DUF3405 PF11885.8 CRK30046.1 - 2.6e-99 333.2 0.2 3.1e-99 333.0 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) zf-RING_UBOX PF13445.6 CRK30047.1 - 8.1e-08 32.2 1.4 8.1e-08 32.2 1.4 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CRK30047.1 - 2.4e-07 30.5 5.2 4.2e-07 29.7 5.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CRK30047.1 - 4.4e-07 29.7 4.3 8.5e-07 28.7 4.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CRK30047.1 - 2.2e-06 27.9 5.3 4.3e-06 26.9 5.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 CRK30047.1 - 2.4e-06 27.4 3.7 4.4e-06 26.5 3.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CRK30047.1 - 2.7e-06 27.1 4.7 1.1e-05 25.2 1.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CRK30047.1 - 2.5e-05 24.4 4.9 0.00019 21.5 5.1 2.1 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 CRK30047.1 - 0.0061 16.4 8.7 0.04 13.8 8.6 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-MIZ PF02891.20 CRK30047.1 - 0.11 12.3 5.2 9.2 6.1 6.1 2.6 1 1 1 2 2 2 0 MIZ/SP-RING zinc finger zf-rbx1 PF12678.7 CRK30047.1 - 0.49 10.7 4.2 1.3 9.3 4.2 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger domain TerY_C PF15616.6 CRK30047.1 - 0.67 10.1 1.9 0.81 9.8 0.4 1.8 2 0 0 2 2 2 0 TerY-C metal binding domain zf-RING_10 PF16685.5 CRK30047.1 - 0.94 9.7 5.8 2.8 8.1 5.8 1.7 1 1 0 1 1 1 0 zinc RING finger of MSL2 zf-ribbon_3 PF13248.6 CRK30047.1 - 1.9 8.0 4.3 3.7 7.1 0.7 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Lar_restr_allev PF14354.6 CRK30047.1 - 4.3 7.8 5.8 9.7 6.7 1.6 2.5 1 1 1 2 2 2 0 Restriction alleviation protein Lar DHO_dh PF01180.21 CRK30048.1 - 3e-22 79.2 0.0 1.9e-21 76.6 0.0 1.8 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase NMO PF03060.15 CRK30048.1 - 0.037 13.4 0.6 0.054 12.9 0.6 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase SCP2 PF02036.17 CRK30049.1 - 2.2e-25 89.1 0.5 2.5e-25 88.9 0.5 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 CRK30049.1 - 3.1e-07 30.7 0.2 3.9e-07 30.4 0.2 1.1 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.6 CRK30049.1 - 0.0023 18.3 0.0 0.0027 18.1 0.0 1.2 1 0 0 1 1 1 1 Sterol carrier protein domain GCS PF03074.16 CRK30051.1 - 1.8e-173 577.0 0.0 2.2e-173 576.8 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase GCS2 PF04107.13 CRK30051.1 - 0.0075 15.6 0.0 2.6 7.3 0.0 2.4 2 0 0 2 2 2 2 Glutamate-cysteine ligase family 2(GCS2) Cyclin PF08613.11 CRK30054.1 - 5.3e-43 147.2 1.0 5.6e-25 88.6 0.1 2.3 2 0 0 2 2 2 2 Cyclin Cwf_Cwc_15 PF04889.12 CRK30054.1 - 0.007 16.1 2.4 0.011 15.5 2.4 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein FAM176 PF14851.6 CRK30054.1 - 0.072 12.7 2.1 11 5.7 2.4 2.4 2 0 0 2 2 2 0 FAM176 family RRN3 PF05327.11 CRK30054.1 - 0.12 10.8 0.7 0.18 10.3 0.7 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Astro_capsid_p PF12226.8 CRK30054.1 - 0.52 9.4 10.3 0.8 8.8 10.3 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein CDC45 PF02724.14 CRK30054.1 - 5.1 5.3 6.7 9 4.5 6.7 1.3 1 0 0 1 1 1 0 CDC45-like protein Glyoxalase PF00903.25 CRK30055.1 - 0.0019 18.4 0.0 0.014 15.6 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Epimerase PF01370.21 CRK30056.1 - 1.6e-12 47.4 0.0 1.9e-12 47.2 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CRK30056.1 - 1.3e-11 44.1 0.0 1.6e-11 43.8 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 CRK30056.1 - 1.9e-10 40.9 0.0 2.3e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 CRK30056.1 - 3e-07 30.2 0.0 3.4e-07 30.0 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 CRK30056.1 - 8e-07 28.9 0.1 1e-06 28.5 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 CRK30056.1 - 1.1e-06 28.0 0.1 0.034 13.3 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein adh_short PF00106.25 CRK30056.1 - 0.00032 20.2 0.0 0.00048 19.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 CRK30056.1 - 0.00052 19.2 0.0 0.00064 18.9 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 CRK30056.1 - 0.00093 18.4 0.0 0.0012 18.1 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 CRK30056.1 - 0.0047 16.9 1.0 0.078 12.9 1.0 2.1 1 1 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 CRK30056.1 - 0.032 14.5 0.0 0.047 13.9 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 CRK30058.1 - 2.4e-18 66.5 1.8 2.7e-18 66.3 1.8 1.1 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 CRK30058.1 - 0.0011 19.1 0.2 0.0013 18.9 0.2 1.1 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase PDH PF02153.17 CRK30058.1 - 0.0049 15.9 0.1 0.0055 15.7 0.1 1.1 1 0 0 1 1 1 1 Prephenate dehydrogenase Shikimate_DH PF01488.20 CRK30058.1 - 0.014 15.5 0.3 0.018 15.1 0.3 1.3 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.23 CRK30058.1 - 0.024 14.6 3.0 0.38 10.7 3.0 2.0 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus CoA_binding PF02629.19 CRK30058.1 - 0.052 14.2 1.1 0.076 13.7 1.1 1.3 1 1 0 1 1 1 0 CoA binding domain Ran_BP1 PF00638.18 CRK30059.1 - 5.6e-48 162.2 0.4 6.7e-48 162.0 0.4 1.1 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 CRK30059.1 - 0.00071 19.5 0.2 0.0036 17.2 0.2 1.9 1 1 0 1 1 1 1 WH1 domain VID27_PH PF17747.1 CRK30059.1 - 0.054 13.8 0.0 0.062 13.6 0.0 1.2 1 0 0 1 1 1 0 VID27 PH-like domain G6PD_N PF00479.22 CRK30061.1 - 0.12 13.0 0.1 0.16 12.6 0.1 1.2 1 0 0 1 1 1 0 Glucose-6-phosphate dehydrogenase, NAD binding domain Peptidase_C1_2 PF03051.15 CRK30062.1 - 8.9e-145 482.8 0.0 1e-144 482.6 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 CRK30062.1 - 3.4e-07 30.6 0.0 0.0063 16.6 0.1 2.8 3 0 0 3 3 3 2 Papain family cysteine protease PRK PF00485.18 CRK30063.1 - 2e-59 200.6 0.0 2.9e-59 200.1 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.6 CRK30063.1 - 3.1e-41 141.1 0.0 4.5e-41 140.6 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_18 PF13238.6 CRK30063.1 - 7.9e-07 29.7 0.0 1.8e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CRK30063.1 - 4.2e-06 27.0 0.0 5.4e-05 23.4 0.0 2.3 1 1 0 1 1 1 1 AAA domain CPT PF07931.12 CRK30063.1 - 4.3e-06 26.7 0.0 1.1e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_17 PF13207.6 CRK30063.1 - 6.3e-06 26.7 1.0 0.93 9.9 0.1 3.4 3 0 0 3 3 3 2 AAA domain ABC_tran PF00005.27 CRK30063.1 - 0.00036 21.1 0.2 0.0021 18.6 0.1 2.0 2 0 0 2 2 2 1 ABC transporter AAA PF00004.29 CRK30063.1 - 0.0053 17.2 0.0 0.016 15.6 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Cytidylate_kin PF02224.18 CRK30063.1 - 0.0059 16.4 0.0 0.063 13.0 0.0 2.2 2 0 0 2 2 2 1 Cytidylate kinase Zeta_toxin PF06414.12 CRK30063.1 - 0.0079 15.5 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin NB-ARC PF00931.22 CRK30063.1 - 0.0089 15.2 0.0 0.017 14.3 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_29 PF13555.6 CRK30063.1 - 0.014 15.1 0.5 0.045 13.5 0.1 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF87 PF01935.17 CRK30063.1 - 0.018 15.1 0.0 0.038 14.1 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain dNK PF01712.19 CRK30063.1 - 0.028 14.3 0.1 1.7 8.4 0.0 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_16 PF13191.6 CRK30063.1 - 0.043 14.2 0.1 0.31 11.4 0.0 2.2 1 1 1 2 2 2 0 AAA ATPase domain NACHT PF05729.12 CRK30063.1 - 0.058 13.3 0.1 0.15 12.0 0.1 1.7 1 0 0 1 1 1 0 NACHT domain APS_kinase PF01583.20 CRK30063.1 - 0.065 13.1 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase RNA_helicase PF00910.22 CRK30063.1 - 0.076 13.4 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Pribosyltran PF00156.27 CRK30063.1 - 0.081 12.4 0.0 0.27 10.7 0.0 1.8 2 0 0 2 2 2 0 Phosphoribosyl transferase domain RsgA_GTPase PF03193.16 CRK30063.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase MMR_HSR1 PF01926.23 CRK30063.1 - 0.14 12.3 0.1 0.32 11.1 0.1 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase NTPase_1 PF03266.15 CRK30063.1 - 0.15 12.0 0.0 0.36 10.7 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA_5 PF07728.14 CRK30063.1 - 0.17 11.9 0.0 0.79 9.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 CRK30063.1 - 0.18 12.3 0.4 0.41 11.1 0.4 1.5 1 0 0 1 1 1 0 AAA domain Helicase_C PF00271.31 CRK30066.1 - 2.1e-17 63.4 0.0 4.5e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 CRK30066.1 - 1.2e-07 31.2 1.3 4.7e-07 29.3 1.3 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 SNF2_N PF00176.23 CRK30066.1 - 3.1e-06 26.1 0.2 4.2e-06 25.7 0.2 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain VirC1 PF07015.11 CRK30066.1 - 0.042 13.2 0.3 0.11 11.8 0.1 1.8 2 0 0 2 2 2 0 VirC1 protein AT_hook PF02178.19 CRK30066.1 - 0.068 13.1 3.0 0.22 11.5 3.0 1.9 1 0 0 1 1 1 0 AT hook motif zinc_ribbon_6 PF14599.6 CRK30070.1 - 3.9e-24 84.4 0.1 3.9e-24 84.4 0.1 4.3 3 1 0 3 3 3 1 Zinc-ribbon zf-CHY PF05495.12 CRK30070.1 - 6.5e-18 65.0 22.9 6.5e-18 65.0 22.9 3.8 2 1 1 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.6 CRK30070.1 - 3.9e-08 33.5 7.7 3.9e-08 33.5 7.7 5.2 3 2 3 6 6 6 1 Ring finger domain zf-C3HC4_2 PF13923.6 CRK30070.1 - 2.2e-05 24.2 8.2 2.2e-05 24.2 8.2 5.0 3 1 4 7 7 7 1 Zinc finger, C3HC4 type (RING finger) Prp18 PF02840.15 CRK30074.1 - 1.5e-51 174.2 0.0 1.5e-51 174.2 0.0 1.8 2 1 0 2 2 2 1 Prp18 domain PRP4 PF08799.11 CRK30074.1 - 5.9e-10 38.5 3.8 5.9e-10 38.5 3.8 3.0 3 0 0 3 3 3 2 pre-mRNA processing factor 4 (PRP4) like ESP PF16590.5 CRK30074.1 - 0.074 13.3 0.1 0.15 12.4 0.1 1.4 1 0 0 1 1 1 0 Exocrine gland-secreting peptide CDC45 PF02724.14 CRK30074.1 - 1.4 7.1 9.1 1.8 6.8 9.1 1.2 1 0 0 1 1 1 0 CDC45-like protein SAP18 PF06487.12 CRK30075.1 - 1e-30 106.8 0.0 1.3e-30 106.4 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) DUF2839 PF10999.8 CRK30077.1 - 0.033 14.6 0.1 0.042 14.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2839) PPR_2 PF13041.6 CRK30079.1 - 4.7e-27 93.9 2.2 6.4e-13 48.7 0.1 6.1 4 2 1 5 5 5 4 PPR repeat family PPR_3 PF13812.6 CRK30079.1 - 4.1e-15 55.6 0.0 3.4e-07 30.2 0.0 5.1 5 1 0 5 5 5 2 Pentatricopeptide repeat domain PPR PF01535.20 CRK30079.1 - 8.6e-11 41.3 3.9 0.0089 16.2 0.4 6.5 6 0 0 6 6 6 2 PPR repeat GST_N PF02798.20 CRK30079.1 - 1.8e-09 37.8 0.0 4.9e-09 36.4 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain PPR_long PF17177.4 CRK30079.1 - 9e-08 31.7 0.0 0.00059 19.3 0.0 3.5 2 1 2 4 4 4 3 Pentacotripeptide-repeat region of PRORP GST_N_3 PF13417.6 CRK30079.1 - 6.8e-07 29.6 0.0 1.6e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain PPR_1 PF12854.7 CRK30079.1 - 1.4e-06 27.9 0.6 0.19 11.4 0.0 5.4 6 0 0 6 6 6 2 PPR repeat GST_C_2 PF13410.6 CRK30079.1 - 1.3e-05 25.1 0.0 4.6e-05 23.4 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CRK30079.1 - 2.4e-05 24.5 0.0 7.5e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 CRK30079.1 - 0.00041 20.6 0.0 0.0015 18.7 0.0 2.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CRK30079.1 - 0.0026 17.9 0.0 0.0094 16.1 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain RPM2 PF08579.11 CRK30079.1 - 0.039 14.4 0.0 0.12 12.8 0.0 1.8 1 0 0 1 1 1 0 Mitochondrial ribonuclease P subunit (RPM2) Mis12 PF05859.12 CRK30081.1 - 1.3e-37 128.8 0.0 2e-37 128.2 0.0 1.3 1 0 0 1 1 1 1 Mis12 protein SUIM_assoc PF16619.5 CRK30081.1 - 0.066 13.3 4.3 0.13 12.3 4.3 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Tmemb_14 PF03647.13 CRK30083.1 - 3e-19 69.5 4.2 6.6e-19 68.4 4.2 1.5 1 0 0 1 1 1 1 Transmembrane proteins 14C AIM3 PF17096.5 CRK30085.1 - 0.00033 21.5 0.1 0.00033 21.5 0.1 4.0 3 2 0 3 3 3 1 Altered inheritance of mitochondria protein 3 Calcipressin PF04847.12 CRK30085.1 - 5.2 6.8 8.7 11 5.7 8.7 1.5 1 0 0 1 1 1 0 Calcipressin TCTP PF00838.17 CRK30087.1 - 4.3e-68 228.8 1.2 5.2e-68 228.6 1.2 1.1 1 0 0 1 1 1 1 Translationally controlled tumour protein FA_hydroxylase PF04116.13 CRK30089.1 - 7e-22 78.2 12.1 7e-22 78.2 12.1 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily YL1 PF05764.13 CRK30093.1 - 1.6e-56 192.2 17.1 1.6e-56 192.2 17.1 3.2 3 0 0 3 3 3 2 YL1 nuclear protein YL1_C PF08265.11 CRK30093.1 - 5.4e-13 48.5 1.7 1e-12 47.6 1.7 1.5 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain AAA_23 PF13476.6 CRK30093.1 - 4.6 7.7 17.3 2.7 8.5 7.6 2.4 2 0 0 2 2 2 0 AAA domain DUF2052 PF09747.9 CRK30094.1 - 3.7e-27 95.7 15.4 3.3e-14 53.5 0.6 2.2 2 0 0 2 2 2 2 Coiled-coil domain containing protein (DUF2052) Glyco_hydro_15 PF00723.21 CRK30097.1 - 1.3e-34 119.8 0.0 5e-32 111.3 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.19 CRK30097.1 - 1.2e-19 70.0 0.0 2.3e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 Starch binding domain AftA_C PF12249.8 CRK30098.1 - 0.047 13.4 0.1 0.1 12.3 0.1 1.6 1 1 0 1 1 1 0 Arabinofuranosyltransferase A C terminal PI-PLC-C1 PF16670.5 CRK30100.1 - 0.0085 15.2 0.0 0.023 13.8 0.0 1.7 2 0 0 2 2 2 1 Phosphoinositide phospholipase C, Ca2+-dependent C1_1 PF00130.22 CRK30101.1 - 0.21 11.5 0.9 0.53 10.2 0.9 1.6 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) CTU2 PF10288.9 CRK30101.1 - 0.21 11.8 0.1 1.4 9.2 0.1 2.0 1 1 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 DUF5418 PF17439.2 CRK30101.1 - 0.22 11.6 3.3 0.32 11.0 3.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5418) DUF1129 PF06570.11 CRK30101.1 - 1.4 8.3 7.5 0.18 11.2 3.5 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) Clat_adaptor_s PF01217.20 CRK30102.1 - 3.4e-51 172.9 1.5 4.6e-51 172.5 1.5 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain ECR1_N PF14382.6 CRK30102.1 - 6.5e-18 64.3 1.2 6.5e-18 64.3 1.2 1.9 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region PulA_N1 PF17999.1 CRK30102.1 - 0.11 13.2 0.1 0.42 11.4 0.0 2.0 2 0 0 2 2 2 0 Pullulanase N1-terminal domain Phage_head_chap PF11113.8 CRK30102.1 - 0.12 12.5 0.0 0.34 11.0 0.0 1.7 1 0 0 1 1 1 0 Head assembly gene product DUF4536 PF15055.6 CRK30103.1 - 1.6e-05 25.1 4.3 2.5e-05 24.4 4.3 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4536) Dynamin_M PF01031.20 CRK30104.1 - 2.2e-80 269.9 0.1 3.9e-80 269.1 0.0 1.4 2 0 0 2 2 2 1 Dynamin central region GED PF02212.18 CRK30104.1 - 2.4e-30 104.5 4.9 4.8e-30 103.6 4.9 1.5 1 0 0 1 1 1 1 Dynamin GTPase effector domain PGK PF00162.19 CRK30105.1 - 9.8e-52 176.1 2.0 1.3e-51 175.7 2.0 1.1 1 0 0 1 1 1 1 Phosphoglycerate kinase Peripla_BP_4 PF13407.6 CRK30105.1 - 0.0017 18.0 0.6 0.0025 17.4 0.6 1.2 1 0 0 1 1 1 1 Periplasmic binding protein domain AlaDh_PNT_C PF01262.21 CRK30105.1 - 0.099 11.9 0.9 0.16 11.2 0.9 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ATP_bind_1 PF03029.17 CRK30106.1 - 3.9e-30 105.4 0.0 4.6e-30 105.2 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 CRK30106.1 - 0.00039 20.8 0.0 0.00044 20.7 0.0 1.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CRK30106.1 - 0.0005 20.4 0.0 0.00058 20.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain PRK PF00485.18 CRK30106.1 - 0.00069 19.4 0.0 0.00084 19.1 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_24 PF13479.6 CRK30106.1 - 0.001 18.8 0.0 0.0014 18.4 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CRK30106.1 - 0.0022 18.1 0.0 0.0028 17.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.22 CRK30106.1 - 0.0037 16.5 0.1 0.0038 16.5 0.1 1.3 1 1 0 1 1 1 1 NB-ARC domain NACHT PF05729.12 CRK30106.1 - 0.0043 17.0 0.0 0.0064 16.4 0.0 1.2 1 0 0 1 1 1 1 NACHT domain AAA_30 PF13604.6 CRK30106.1 - 0.0057 16.4 0.0 0.0076 16.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 CRK30106.1 - 0.011 15.4 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain G-alpha PF00503.20 CRK30106.1 - 0.013 14.7 0.0 0.013 14.7 0.0 1.3 1 1 0 1 1 1 0 G-protein alpha subunit Zeta_toxin PF06414.12 CRK30106.1 - 0.015 14.6 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin ATPase_2 PF01637.18 CRK30106.1 - 0.034 14.0 0.0 0.038 13.9 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea KTI12 PF08433.10 CRK30106.1 - 0.05 13.0 0.0 0.078 12.4 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 cobW PF02492.19 CRK30106.1 - 0.051 13.2 0.1 0.076 12.6 0.0 1.3 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 CRK30106.1 - 0.059 12.9 0.0 0.077 12.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region CLP1_P PF16575.5 CRK30106.1 - 0.082 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Pox_A32 PF04665.12 CRK30106.1 - 0.091 12.2 0.0 0.13 11.6 0.0 1.3 1 1 0 1 1 1 0 Poxvirus A32 protein AAA_14 PF13173.6 CRK30106.1 - 0.12 12.4 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CRK30106.1 - 0.17 12.4 0.1 0.19 12.3 0.1 1.3 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 CRK30106.1 - 0.19 11.7 0.0 0.28 11.2 0.0 1.2 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Fungal_trans PF04082.18 CRK30107.1 - 4.7e-12 45.5 0.0 8.2e-12 44.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pkinase PF00069.25 CRK30107.1 - 3e-11 43.2 0.0 6.5e-06 25.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Zn_clus PF00172.18 CRK30107.1 - 4.5e-09 36.3 7.9 9e-09 35.3 7.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase_Tyr PF07714.17 CRK30107.1 - 0.0021 17.4 0.0 0.0041 16.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_2 PF07719.17 CRK30107.1 - 0.011 15.8 0.0 7.2 7.0 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat UBA PF00627.31 CRK30107.1 - 0.011 15.6 0.1 0.024 14.6 0.1 1.6 1 0 0 1 1 1 0 UBA/TS-N domain TPR_12 PF13424.6 CRK30107.1 - 0.042 14.1 0.1 0.042 14.1 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 CRK30107.1 - 0.051 13.4 0.0 0.63 10.0 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat CENP-B_dimeris PF09026.10 CRK30107.1 - 3.3 8.2 7.1 11 6.4 7.1 1.9 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Cupin_2 PF07883.11 CRK30108.1 - 2.1e-10 40.2 0.4 3.5e-10 39.4 0.4 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 CRK30108.1 - 0.00012 21.7 0.0 0.00014 21.5 0.0 1.2 1 0 0 1 1 1 1 Cupin NAD_binding_2 PF03446.15 CRK30109.1 - 2.7e-35 121.9 0.0 4.4e-35 121.2 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 CRK30109.1 - 5e-29 101.0 0.0 8.7e-29 100.2 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 CRK30109.1 - 0.00027 21.5 0.0 0.00064 20.2 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent OCD_Mu_crystall PF02423.15 CRK30109.1 - 0.0012 17.9 0.1 0.0019 17.2 0.1 1.3 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Ldh_1_N PF00056.23 CRK30109.1 - 0.0069 16.5 0.0 0.018 15.2 0.0 1.6 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 CRK30109.1 - 0.13 13.1 0.0 0.3 11.9 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold 3HCDH_N PF02737.18 CRK30109.1 - 0.15 11.9 1.2 1.9 8.4 1.1 2.3 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rho_GDI PF02115.17 CRK30110.1 - 7.7e-54 182.4 13.0 8.5e-54 182.3 9.1 2.6 2 1 0 2 2 2 1 RHO protein GDP dissociation inhibitor Presenilin PF01080.17 CRK30110.1 - 4.4 5.9 6.5 6.4 5.4 6.5 1.2 1 0 0 1 1 1 0 Presenilin Metallophos PF00149.28 CRK30111.1 - 1e-36 127.4 0.7 1.3e-36 127.0 0.7 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Egh16-like PF11327.8 CRK30113.1 - 2.2e-65 220.5 10.3 2.9e-65 220.1 10.3 1.1 1 0 0 1 1 1 1 Egh16-like virulence factor WD40 PF00400.32 CRK30116.1 - 1.8e-55 183.6 14.0 5e-11 43.0 0.2 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK30116.1 - 3.3e-25 88.2 0.0 0.0018 18.5 0.0 6.3 3 2 3 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CRK30116.1 - 2.1e-11 43.4 0.6 0.15 11.0 0.0 5.3 2 2 2 5 5 5 4 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 CRK30116.1 - 4.8e-06 26.6 0.0 0.076 12.9 0.0 3.2 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 CRK30116.1 - 1.2e-05 24.2 2.9 0.11 11.1 0.0 4.5 2 2 3 5 5 5 2 Nucleoporin Nup120/160 PD40 PF07676.12 CRK30116.1 - 3.8e-05 23.5 1.1 2.3 8.2 0.0 4.4 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Frtz PF11768.8 CRK30116.1 - 0.00035 19.0 0.0 0.14 10.4 0.0 2.4 3 0 0 3 3 3 2 WD repeat-containing and planar cell polarity effector protein Fritz Cytochrom_D1 PF02239.16 CRK30116.1 - 0.0026 16.3 0.0 0.32 9.5 0.0 2.8 2 1 1 3 3 3 1 Cytochrome D1 heme domain VID27 PF08553.10 CRK30116.1 - 0.004 16.3 0.0 0.63 9.0 0.0 3.4 4 0 0 4 4 4 1 VID27 C-terminal WD40-like domain Plasmodium_HRP PF05403.11 CRK30116.1 - 0.0062 16.4 14.3 0.0062 16.4 14.3 1.5 2 0 0 2 2 2 1 Plasmodium histidine-rich protein (HRPII/III) PALB2_WD40 PF16756.5 CRK30116.1 - 0.0094 14.9 0.1 0.73 8.7 0.0 3.1 3 1 1 4 4 4 1 Partner and localizer of BRCA2 WD40 domain WD40_like PF17005.5 CRK30116.1 - 0.011 15.1 0.0 0.12 11.7 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain Nucleoporin_N PF08801.11 CRK30116.1 - 0.068 11.9 0.0 4.2 6.0 0.0 3.1 2 1 0 2 2 2 0 Nup133 N terminal like GH115_C PF17829.1 CRK30118.1 - 2.1e-47 161.2 0.0 3.6e-47 160.4 0.0 1.4 1 0 0 1 1 1 1 Gylcosyl hydrolase family 115 C-terminal domain Kinesin PF00225.23 CRK30120.1 - 3.5e-33 115.0 0.1 5.4e-33 114.3 0.1 1.3 1 0 0 1 1 1 1 Kinesin motor domain Herpes_UL14 PF03580.14 CRK30120.1 - 0.019 15.2 2.8 0.072 13.3 2.0 2.2 2 0 0 2 2 2 0 Herpesvirus UL14-like protein DUF2526 PF10735.9 CRK30120.1 - 0.18 12.0 2.1 0.68 10.1 2.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2526) Thaumatin PF00314.17 CRK30121.1 - 1.6e-41 142.3 0.1 2e-41 142.0 0.1 1.1 1 0 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 CRK30121.1 - 0.17 11.1 0.0 0.29 10.4 0.0 1.4 2 0 0 2 2 2 0 Beta-1,3-glucanase Pkinase PF00069.25 CRK30122.1 - 5.1e-22 78.5 0.0 8e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK30122.1 - 7.5e-11 41.8 0.0 3.8e-10 39.5 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 CRK30122.1 - 7.9e-05 22.1 0.1 0.00012 21.5 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RabGAP-TBC PF00566.18 CRK30123.1 - 3e-10 40.1 0.0 8.3e-10 38.7 0.0 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Hamartin PF04388.12 CRK30124.1 - 2.1 6.9 7.7 2.3 6.8 7.7 1.0 1 0 0 1 1 1 0 Hamartin protein TFIIF_alpha PF05793.12 CRK30125.1 - 0.28 9.7 28.4 0.31 9.6 28.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BUD22 PF09073.10 CRK30125.1 - 3.5 6.9 31.3 4.8 6.4 31.3 1.2 1 0 0 1 1 1 0 BUD22 CH PF00307.31 CRK30127.1 - 2.5e-28 98.4 0.1 3.7e-19 68.9 0.0 2.2 2 0 0 2 2 2 2 Calponin homology (CH) domain Mito_carr PF00153.27 CRK30127.1 - 5.5e-09 35.8 0.0 8.6e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial carrier protein WD40 PF00400.32 CRK30128.1 - 2.2e-06 28.3 0.2 0.032 15.1 0.0 2.2 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK30128.1 - 2.5e-05 24.5 0.0 0.031 14.6 0.0 2.1 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain VID27 PF08553.10 CRK30128.1 - 0.17 10.9 0.0 0.19 10.7 0.0 1.0 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain Response_reg PF00072.24 CRK30130.1 - 1e-21 77.2 0.1 1.4e-21 76.8 0.1 1.2 1 0 0 1 1 1 1 Response regulator receiver domain HTH_24 PF13412.6 CRK30130.1 - 0.046 13.3 0.1 0.089 12.4 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding ASF1_hist_chap PF04729.13 CRK30131.1 - 1.8e-52 177.3 0.0 2.9e-52 176.7 0.0 1.3 1 0 0 1 1 1 1 ASF1 like histone chaperone DUF4452 PF14618.6 CRK30133.1 - 9.6e-76 253.4 10.7 1.1e-75 253.2 10.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) Chorismate_bind PF00425.18 CRK30134.1 - 5.1e-31 108.2 0.0 6.7e-31 107.8 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme POR PF01558.18 CRK30134.1 - 0.0068 16.5 0.0 0.0091 16.1 0.0 1.2 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase VMA21 PF09446.10 CRK30135.1 - 7.1e-14 51.7 12.2 9.8e-14 51.2 12.2 1.2 1 0 0 1 1 1 1 VMA21-like domain Methyltransf_34 PF11312.8 CRK30136.1 - 6.7e-106 354.0 0.0 7.8e-106 353.8 0.0 1.0 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase Stb3 PF10330.9 CRK30138.1 - 0.14 12.2 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative Sin3 binding protein Acyl_transf_3 PF01757.22 CRK30139.1 - 1.4e-35 123.0 17.0 2.4e-35 122.2 17.0 1.4 1 1 0 1 1 1 1 Acyltransferase family Glyco_hydro_43 PF04616.14 CRK30140.1 - 4.5e-37 127.9 6.3 5.2e-37 127.7 6.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 ImmE5 PF11480.8 CRK30140.1 - 0.15 12.6 0.7 4.5 7.8 0.2 2.5 1 1 1 2 2 2 0 Colicin-E5 Imm protein Glyco_hydro_43 PF04616.14 CRK30141.1 - 6.7e-54 183.2 2.5 7.9e-54 182.9 2.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Methyltr_RsmB-F PF01189.17 CRK30143.1 - 1.2e-17 64.2 0.1 3.2e-11 43.2 0.0 2.4 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F Bac_rhamnosid6H PF17389.2 CRK30145.1 - 6e-17 61.9 0.1 1.1e-16 61.0 0.1 1.4 1 1 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Glyco_hydro_2_N PF02837.18 CRK30145.1 - 0.015 15.2 0.0 0.033 14.1 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_36 PF17167.4 CRK30145.1 - 0.021 13.5 0.0 0.037 12.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase 36 superfamily, catalytic domain Glyco_hydro_79C PF16862.5 CRK30146.1 - 1.1e-21 77.6 1.8 2.8e-21 76.3 1.8 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain Caudal_act PF04731.12 CRK30146.1 - 0.0068 16.8 0.5 0.0068 16.8 0.5 2.3 2 0 0 2 2 2 1 Caudal like protein activation region Sugar_tr PF00083.24 CRK30147.1 - 6.2e-43 147.3 10.6 7.7e-43 147.0 10.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK30147.1 - 4.7e-07 29.1 11.4 4.7e-07 29.1 11.4 2.4 1 1 2 3 3 3 2 Major Facilitator Superfamily Rep_N PF08724.10 CRK30147.1 - 0.062 13.0 0.1 0.099 12.4 0.1 1.2 1 0 0 1 1 1 0 Rep protein catalytic domain like 4HBT PF03061.22 CRK30149.1 - 5.9e-07 29.8 0.0 9.4e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.17 CRK30149.1 - 0.00011 21.6 1.1 0.00017 21.0 1.1 1.2 1 0 0 1 1 1 1 Acyl-ACP thioesterase 4HBT_2 PF13279.6 CRK30149.1 - 0.00014 22.4 0.0 0.00016 22.1 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily LPMO_10 PF03067.15 CRK30150.1 - 1.1e-08 36.0 4.0 1.4e-08 35.6 4.0 1.3 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading PAP_assoc PF03828.19 CRK30151.1 - 2.2e-12 47.0 0.1 3.7e-12 46.3 0.1 1.4 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 CRK30151.1 - 1e-07 32.1 0.0 1.6e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyltransferase domain eIF-5a PF01287.20 CRK30152.1 - 7.7e-05 22.7 0.0 0.00013 22.0 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold Glyco_transf_34 PF05637.12 CRK30155.1 - 5.3e-08 32.9 0.9 7.8e-08 32.3 0.9 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family ubiquitin PF00240.23 CRK30156.1 - 2.7e-18 65.5 0.0 3.7e-18 65.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CRK30156.1 - 0.00011 21.9 0.0 0.00018 21.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 CRK30156.1 - 0.00052 20.5 0.0 0.00086 19.8 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 CRK30156.1 - 0.00087 19.4 0.0 0.0014 18.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like STI1 PF17830.1 CRK30156.1 - 0.53 10.3 23.7 0.38 10.7 9.9 3.1 2 1 1 3 3 3 0 STI1 domain CENP-F_leu_zip PF10473.9 CRK30157.1 - 0.016 15.2 23.9 0.016 15.2 23.9 4.3 1 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 CRK30157.1 - 5.4 7.2 98.1 15 5.7 33.0 3.6 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) IFT57 PF10498.9 CRK30157.1 - 6.2 5.7 58.1 0.051 12.5 1.0 3.0 1 1 2 3 3 3 0 Intra-flagellar transport protein 57 Tyrosinase PF00264.20 CRK30158.1 - 3.5e-15 56.9 1.3 4.4e-15 56.6 1.3 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Polyoma_agno PF01736.16 CRK30159.1 - 0.28 11.0 1.6 16 5.3 0.1 2.3 2 0 0 2 2 2 0 Polyomavirus agnoprotein CbtB PF09489.10 CRK30159.1 - 0.34 11.0 0.3 0.34 11.0 0.3 2.5 2 1 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) Asp PF00026.23 CRK30165.1 - 9.9e-63 212.4 2.2 1.2e-62 212.2 2.2 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CRK30165.1 - 3.8e-08 33.8 0.5 0.0089 16.3 0.0 2.4 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 CRK30165.1 - 0.0099 16.5 4.0 0.12 13.1 0.7 3.5 3 1 0 3 3 3 1 Aspartyl protease TAXi_C PF14541.6 CRK30165.1 - 0.02 14.7 0.1 0.047 13.5 0.1 1.6 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 CRK30165.1 - 1.7 9.3 3.7 1.7 9.3 0.2 2.9 3 1 0 3 3 3 0 gag-polyprotein putative aspartyl protease Aminotran_5 PF00266.19 CRK30167.1 - 5.2e-18 65.1 0.0 2.4e-17 62.9 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class-V Glyco_hydro_3_C PF01915.22 CRK30169.1 - 2.7e-48 164.7 0.3 5e-48 163.8 0.3 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 CRK30169.1 - 4.5e-35 121.5 0.0 7.4e-35 120.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 CRK30169.1 - 1.2e-26 92.6 0.0 2.6e-26 91.5 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Rick_17kDa_Anti PF05433.15 CRK30171.1 - 3.7e-06 26.7 10.7 8.3e-06 25.6 10.7 1.6 1 0 0 1 1 1 1 Glycine zipper 2TM domain DUF1269 PF06897.12 CRK30171.1 - 0.03 14.6 1.0 0.055 13.8 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) Gly-zipper_YMGG PF13441.6 CRK30171.1 - 0.3 10.9 11.4 0.67 9.7 11.4 1.7 1 0 0 1 1 1 0 YMGG-like Gly-zipper zf-C2HC5 PF06221.13 CRK30175.1 - 7.5e-20 70.7 5.4 1.2e-19 70.1 5.4 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Ldh_1_C PF02866.18 CRK30177.1 - 3e-13 50.0 0.0 3.3e-13 49.9 0.0 1.0 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain E1-E2_ATPase PF00122.20 CRK30178.1 - 9.7e-15 54.6 0.0 2.3e-14 53.3 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 CRK30178.1 - 7.3e-14 52.5 2.4 1.1e-07 32.3 2.8 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CRK30178.1 - 6.9e-05 22.8 0.0 0.00029 20.9 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CRK30178.1 - 0.0048 16.7 0.1 0.057 13.1 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Na_H_Exchanger PF00999.21 CRK30179.1 - 5.7e-31 107.7 39.6 8.8e-31 107.0 39.6 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Fst_toxin PF13955.6 CRK30179.1 - 0.038 13.9 1.1 0.14 12.1 1.1 2.1 1 0 0 1 1 1 0 Toxin Fst, type I toxin-antitoxin system E1-E2_ATPase PF00122.20 CRK30181.1 - 9.6e-42 142.5 3.6 5.2e-39 133.6 0.5 2.1 2 0 0 2 2 2 2 E1-E2 ATPase Cation_ATPase PF13246.6 CRK30181.1 - 4.3e-09 36.3 0.0 7.5e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) DUF2157 PF09925.9 CRK30181.1 - 0.0013 18.5 1.5 0.039 13.7 0.1 2.3 2 0 0 2 2 2 1 Predicted membrane protein (DUF2157) DUF2231 PF09990.9 CRK30181.1 - 0.014 15.8 0.4 0.014 15.8 0.4 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2231) PGG PF13962.6 CRK30181.1 - 0.12 12.2 2.0 0.17 11.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF4181 PF13789.6 CRK30181.1 - 0.91 9.8 4.3 0.6 10.4 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4181) DUF3262 PF11660.8 CRK30181.1 - 4.5 7.7 7.9 4.6 7.7 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3262) Baculo_11_kDa PF06143.11 CRK30181.1 - 7.8 6.2 9.1 1.6 8.4 3.7 2.4 2 0 0 2 2 2 0 Baculovirus 11 kDa family ANAPC4_WD40 PF12894.7 CRK30183.1 - 3.2e-09 37.0 0.0 2.3 8.6 0.0 5.4 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CRK30183.1 - 4e-08 33.8 17.4 0.0067 17.3 0.2 7.8 9 1 0 9 9 9 2 WD domain, G-beta repeat Nup160 PF11715.8 CRK30183.1 - 0.00013 20.8 0.0 0.12 11.0 0.0 2.7 2 1 1 3 3 3 2 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 CRK30183.1 - 0.0029 16.6 0.0 0.38 9.6 0.0 2.2 2 0 0 2 2 2 2 Partner and localizer of BRCA2 WD40 domain ENTH PF01417.20 CRK30184.1 - 8.3e-47 158.3 0.1 1.2e-46 157.9 0.1 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 CRK30184.1 - 0.00014 21.0 0.1 0.00017 20.7 0.1 1.1 1 0 0 1 1 1 1 ANTH domain ComGF PF15980.5 CRK30184.1 - 0.076 13.4 0.0 0.18 12.2 0.0 1.6 1 1 0 1 1 1 0 Putative Competence protein ComGF Histone PF00125.24 CRK30187.1 - 3.4e-17 63.0 0.0 4.4e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 CRK30187.1 - 7.9e-13 47.9 0.1 1.9e-12 46.7 0.1 1.7 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 CRK30187.1 - 0.00019 21.7 0.0 0.00026 21.2 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RasGEF PF00617.19 CRK30188.1 - 1.2e-13 51.6 0.3 2.2e-13 50.8 0.3 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 CRK30188.1 - 1.8e-12 47.4 0.0 4.2e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif Fungal_trans PF04082.18 CRK30191.1 - 7.8e-14 51.3 0.6 1.4e-13 50.5 0.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK30191.1 - 2.1e-06 27.7 14.2 4e-06 26.8 14.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PS_pyruv_trans PF04230.13 CRK30191.1 - 0.088 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide pyruvyl transferase Abhydrolase_3 PF07859.13 CRK30192.1 - 3.6e-13 49.9 0.0 5.4e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CRK30192.1 - 0.0018 17.8 0.0 0.0049 16.4 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 CRK30192.1 - 0.077 13.6 5.9 0.1 13.2 5.9 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family ADH_zinc_N PF00107.26 CRK30193.1 - 6.3e-09 35.9 0.1 1.3e-08 34.9 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CRK30193.1 - 4.4e-07 29.8 0.4 2.7e-06 27.2 0.1 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain TmoB PF06234.12 CRK30193.1 - 0.02 15.0 0.0 0.16 12.1 0.0 2.2 2 0 0 2 2 2 0 Toluene-4-monooxygenase system protein B (TmoB) Peptidase_M28 PF04389.17 CRK30195.1 - 2.7e-11 43.5 0.4 4.5e-11 42.8 0.4 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 CRK30195.1 - 1e-08 35.1 0.9 5.8e-08 32.7 0.1 2.3 2 0 0 2 2 2 1 PA domain TauD PF02668.16 CRK30196.1 - 3.2e-46 158.3 0.0 4.3e-46 157.9 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Ax_dynein_light PF10211.9 CRK30196.1 - 0.017 15.1 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 Axonemal dynein light chain UL16 PF17622.2 CRK30196.1 - 0.14 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Viral unique long protein 16 MFS_1 PF07690.16 CRK30197.1 - 3e-15 56.0 21.6 4.4e-15 55.4 21.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_16 PF00722.21 CRK30198.1 - 0.00034 20.1 0.0 0.0023 17.5 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 OB_NTP_bind PF07717.16 CRK30199.1 - 6.3e-16 58.5 0.1 1.4e-15 57.4 0.1 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold S1 PF00575.23 CRK30199.1 - 6.2e-12 45.7 0.3 1.1e-11 44.9 0.3 1.4 1 0 0 1 1 1 1 S1 RNA binding domain Spem1 PF15670.5 CRK30199.1 - 9.6 5.7 8.7 19 4.7 8.7 1.4 1 0 0 1 1 1 0 Spermatid maturation protein 1 IPK PF03770.16 CRK30200.1 - 1e-17 64.7 0.0 1.1e-17 64.5 0.0 1.0 1 0 0 1 1 1 1 Inositol polyphosphate kinase DUF1168 PF06658.12 CRK30201.1 - 1.6e-35 121.9 11.3 1.6e-35 121.9 11.3 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1168) Macoilin PF09726.9 CRK30201.1 - 0.25 9.9 3.3 0.26 9.8 3.3 1.1 1 0 0 1 1 1 0 Macoilin family DUF966 PF06136.13 CRK30201.1 - 0.44 10.2 5.5 0.57 9.8 5.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) CDC45 PF02724.14 CRK30201.1 - 5.3 5.2 7.8 6.5 4.9 7.8 1.1 1 0 0 1 1 1 0 CDC45-like protein TruB_N PF01509.18 CRK30202.1 - 1e-43 149.2 0.0 2.2e-43 148.2 0.0 1.5 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 CRK30202.1 - 6.5e-06 26.2 0.0 1.3e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain GAGA_bind PF06217.12 CRK30202.1 - 5.3 7.2 13.3 3.2 7.9 4.7 2.1 2 0 0 2 2 2 0 GAGA binding protein-like family Tim17 PF02466.19 CRK30203.1 - 0.024 15.0 0.1 0.031 14.7 0.1 1.1 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family TRAM_LAG1_CLN8 PF03798.16 CRK30204.1 - 4.4e-28 98.4 8.5 4.4e-28 98.4 8.5 2.0 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 CRK30204.1 - 9.2e-23 79.7 0.1 9.2e-23 79.7 0.1 2.2 2 0 0 2 2 2 1 TRAM1-like protein PP1_bind PF15276.6 CRK30204.1 - 0.021 15.1 0.5 0.04 14.2 0.5 1.4 1 0 0 1 1 1 0 Protein phosphatase 1 binding MFS_1 PF07690.16 CRK30205.1 - 4.2e-19 68.7 28.0 2.8e-17 62.7 27.4 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Orf78 PF06024.12 CRK30205.1 - 0.013 15.8 0.0 0.033 14.5 0.0 1.7 1 0 0 1 1 1 0 Orf78 (ac78) DUF5367 PF17329.2 CRK30205.1 - 0.16 12.1 5.2 0.26 11.5 0.9 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5367) DUF1772 PF08592.11 CRK30205.1 - 0.94 9.8 10.5 4.7 7.5 0.7 3.2 1 1 1 3 3 3 0 Domain of unknown function (DUF1772) Sec5 PF15469.6 CRK30206.1 - 4.7e-11 42.8 0.1 6.8e-11 42.3 0.1 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec5 Citrate_synt PF00285.21 CRK30207.1 - 8.9e-102 340.8 0.0 1.1e-101 340.5 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Eclosion PF04736.12 CRK30207.1 - 0.05 13.3 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 Eclosion hormone Bac_rhamnosid_C PF17390.2 CRK30208.1 - 1.4e-09 37.6 0.1 2.1e-09 37.0 0.1 1.3 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain DUF2939 PF11159.8 CRK30208.1 - 0.011 16.1 1.0 1.2 9.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2939) Nup96 PF12110.8 CRK30209.1 - 4.4e-96 321.4 0.8 8.1e-96 320.6 0.8 1.5 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 CRK30209.1 - 3e-51 173.4 0.0 5.9e-51 172.5 0.0 1.5 1 0 0 1 1 1 1 Nucleoporin autopeptidase ENTH PF01417.20 CRK30209.1 - 7.2e-48 161.8 0.0 1.2e-47 161.0 0.0 1.4 1 0 0 1 1 1 1 ENTH domain ABC2_membrane_3 PF12698.7 CRK30209.1 - 2.3e-28 99.3 27.1 3.4e-18 65.9 12.1 3.1 3 0 0 3 3 3 2 ABC-2 family transporter protein ABC_tran PF00005.27 CRK30209.1 - 2.9e-27 95.9 0.0 8.8e-27 94.3 0.0 1.9 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CRK30209.1 - 2.8e-15 56.9 0.9 8.2e-05 22.5 0.0 3.8 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system Zn_clus PF00172.18 CRK30209.1 - 2.8e-08 33.8 13.4 4.5e-08 33.1 13.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Nucleoporin_FG PF13634.6 CRK30209.1 - 0.00022 22.0 119.8 0.0016 19.3 31.7 13.9 2 1 10 12 12 7 7 Nucleoporin FG repeat region DUF4162 PF13732.6 CRK30209.1 - 0.0038 17.9 0.0 1.7 9.4 0.0 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4162) RsgA_GTPase PF03193.16 CRK30209.1 - 0.055 13.4 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase UIM PF02809.20 CRK30209.1 - 0.9 9.6 6.2 0.34 10.9 0.9 2.7 2 0 0 2 2 2 0 Ubiquitin interaction motif Rad4 PF03835.15 CRK30211.1 - 5.7e-31 107.2 0.3 1.2e-30 106.2 0.3 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 CRK30211.1 - 3.1e-27 94.8 0.0 6.6e-27 93.7 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 CRK30211.1 - 9.6e-22 76.6 0.0 2.2e-21 75.5 0.0 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 CRK30211.1 - 3.1e-17 63.3 0.6 3.1e-17 63.3 0.6 3.2 3 1 0 3 3 3 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 CRK30211.1 - 0.0021 18.5 1.0 0.007 16.8 0.2 2.4 2 1 0 2 2 2 1 Transglutaminase-like superfamily P_proprotein PF01483.20 CRK30213.1 - 6e-27 93.5 0.9 6e-27 93.5 0.9 1.7 2 0 0 2 2 2 1 Proprotein convertase P-domain Peptidase_S8 PF00082.22 CRK30213.1 - 2.8e-23 82.6 0.3 5.1e-23 81.8 0.3 1.4 1 0 0 1 1 1 1 Subtilase family RRM_1 PF00076.22 CRK30214.1 - 1.4e-15 56.9 0.0 1.8e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CRK30214.1 - 0.00016 21.7 0.0 0.00021 21.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif Nup35_RRM_2 PF14605.6 CRK30214.1 - 0.029 14.4 0.0 0.057 13.4 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 CRK30214.1 - 0.056 13.5 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Limkain b1 Lactonase PF10282.9 CRK30215.1 - 1.1e-21 77.6 0.0 1.3e-21 77.3 0.0 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller HATPase_c PF02518.26 CRK30216.1 - 3.8e-31 107.9 0.3 1e-30 106.5 0.1 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 CRK30216.1 - 1.5e-17 63.3 0.5 1.5e-17 63.3 0.5 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 CRK30216.1 - 0.00027 21.3 0.1 0.00077 19.8 0.1 1.9 1 0 0 1 1 1 1 HAMP domain LPP PF04728.13 CRK30216.1 - 0.15 12.5 3.8 5.1 7.6 1.9 2.6 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Syntaxin_2 PF14523.6 CRK30216.1 - 0.49 10.8 3.6 2.7 8.4 1.8 2.6 1 1 0 2 2 2 0 Syntaxin-like protein DHC_N2 PF08393.13 CRK30217.1 - 3.7e-52 177.8 0.1 5.7e-52 177.2 0.1 1.3 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 CRK30217.1 - 8.5e-48 163.0 0.2 1.9e-47 161.9 0.0 1.7 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DUF3887 PF13026.6 CRK30217.1 - 0.022 15.6 0.1 1.7 9.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3887) DUF3087 PF11286.8 CRK30217.1 - 0.11 12.0 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) AAA_22 PF13401.6 CRK30217.1 - 0.12 12.7 0.1 0.48 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 CRK30217.1 - 0.12 12.8 0.2 0.71 10.3 0.0 2.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Oxidored_nitro PF00148.19 CRK30217.1 - 0.15 10.8 0.0 0.24 10.1 0.0 1.3 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase AAA_6 PF12774.7 CRK30219.1 - 8.1e-91 304.4 0.1 1.1e-90 303.9 0.1 1.2 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region AAA_5 PF07728.14 CRK30219.1 - 1.9e-18 66.8 0.0 1.1e-12 48.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 CRK30219.1 - 0.0012 18.4 0.1 0.0084 15.6 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_22 PF13401.6 CRK30219.1 - 0.015 15.5 0.0 0.035 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CRK30219.1 - 0.028 14.6 0.0 0.055 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CRK30219.1 - 0.054 13.2 0.0 0.22 11.3 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain Mg_chelatase PF01078.21 CRK30219.1 - 0.095 12.1 0.1 1.2 8.5 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 CRK30219.1 - 0.1 11.7 0.0 0.23 10.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_9 PF12781.7 CRK30221.1 - 5.1e-75 251.4 1.2 6.4e-75 251.1 1.2 1.1 1 0 0 1 1 1 1 ATP-binding dynein motor region FapA PF03961.13 CRK30221.1 - 0.079 11.6 0.4 0.11 11.1 0.4 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A MbeB_N PF04837.12 CRK30221.1 - 0.12 12.7 1.5 0.29 11.5 0.1 2.4 2 0 0 2 2 2 0 MbeB-like, N-term conserved region DUF2267 PF10025.9 CRK30222.1 - 0.011 16.0 0.2 0.02 15.1 0.2 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) Baculo_PEP_C PF04513.12 CRK30222.1 - 0.042 13.9 0.2 0.083 12.9 0.2 1.6 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus PilJ PF13675.6 CRK30222.1 - 0.094 12.7 0.2 0.16 12.0 0.2 1.4 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Glyco_transf_34 PF05637.12 CRK30223.1 - 6.9e-10 39.1 0.3 2.4e-09 37.3 0.2 1.9 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Nucleotid_trans PF03407.16 CRK30223.1 - 1.9e-08 34.6 0.1 3.5e-08 33.7 0.1 1.5 1 1 0 1 1 1 1 Nucleotide-diphospho-sugar transferase DUF273 PF03314.14 CRK30223.1 - 0.032 13.8 0.0 0.056 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF273 MFS_1 PF07690.16 CRK30224.1 - 2.8e-20 72.5 40.0 2.1e-12 46.7 23.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Tma16 PF11176.8 CRK30225.1 - 3e-46 156.9 0.4 3.9e-46 156.6 0.4 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 Hypoth_Ymh PF09509.10 CRK30225.1 - 0.11 12.4 0.3 0.17 11.8 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (Hypoth_ymh) XPG_N PF00752.17 CRK30226.1 - 5.5e-22 78.1 0.0 1.1e-21 77.1 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 CRK30226.1 - 1.3e-21 76.7 0.0 3e-21 75.6 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 CRK30226.1 - 6.9e-05 22.4 0.1 0.0018 17.8 0.0 2.3 2 0 0 2 2 2 1 XPG domain containing FAD_binding_3 PF01494.19 CRK30227.1 - 2.7e-28 99.3 0.0 9.5e-28 97.4 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 CRK30227.1 - 4.6e-06 25.9 0.0 0.0053 15.8 0.0 2.1 2 0 0 2 2 2 2 Squalene epoxidase DAO PF01266.24 CRK30227.1 - 0.00089 18.9 0.3 0.14 11.7 0.2 2.1 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CRK30227.1 - 0.0053 17.0 0.1 0.011 15.9 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 CRK30227.1 - 0.028 15.0 0.1 7 7.3 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CRK30227.1 - 0.074 12.3 0.0 12 5.0 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_10 PF13460.6 CRK30228.1 - 5.4e-31 107.9 0.3 6.1e-31 107.7 0.3 1.0 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 CRK30228.1 - 6.3e-07 29.2 0.2 1.1e-06 28.4 0.2 1.4 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 CRK30228.1 - 0.00012 21.6 0.0 0.00016 21.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ELFV_dehydrog PF00208.21 CRK30228.1 - 0.019 14.7 0.1 0.03 14.1 0.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TrkA_N PF02254.18 CRK30228.1 - 0.033 14.5 0.0 0.065 13.5 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain DapB_N PF01113.20 CRK30228.1 - 0.034 14.3 0.1 0.055 13.6 0.1 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus GDP_Man_Dehyd PF16363.5 CRK30228.1 - 0.077 12.4 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 CRK30228.1 - 0.11 11.6 0.1 0.17 11.0 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain F420_oxidored PF03807.17 CRK30228.1 - 0.12 13.0 0.1 0.23 12.1 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent PGK PF00162.19 CRK30229.1 - 2.3e-104 349.3 1.8 2.6e-104 349.2 1.8 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PA PF02225.22 CRK30229.1 - 0.019 15.0 0.0 0.19 11.8 0.0 2.5 2 1 1 3 3 3 0 PA domain Cpn60_TCP1 PF00118.24 CRK30230.1 - 3.7e-100 335.9 9.5 4.2e-100 335.7 9.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family RRM_1 PF00076.22 CRK30231.1 - 8e-32 108.9 0.1 1.6e-20 72.7 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 CRK30231.1 - 4.7e-24 85.3 0.7 1e-23 84.2 0.3 1.9 2 0 0 2 2 2 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_occluded PF16842.5 CRK30231.1 - 0.003 17.4 0.0 0.3 11.0 0.0 2.7 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_3 PF08777.11 CRK30231.1 - 0.018 15.1 0.6 0.17 12.0 0.0 2.6 3 1 1 4 4 4 0 RNA binding motif RRM_5 PF13893.6 CRK30231.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 CRK30231.1 - 0.19 12.0 0.0 0.34 11.1 0.0 1.4 1 0 0 1 1 1 0 RRM-like domain Adaptin_N PF01602.20 CRK30233.1 - 1.8e-71 241.3 0.4 2e-71 241.2 0.4 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.6 CRK30233.1 - 1.1e-05 25.8 0.3 6.9 7.1 0.0 4.7 2 1 3 5 5 5 4 HEAT repeats RTP1_C1 PF10363.9 CRK30233.1 - 0.12 12.6 0.3 0.79 9.9 0.1 2.4 2 1 1 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 NPA PF16469.5 CRK30233.1 - 0.16 12.6 0.0 0.33 11.5 0.0 1.5 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 RabGAP-TBC PF00566.18 CRK30234.1 - 1.1e-30 106.9 2.0 1.1e-30 106.9 2.0 1.9 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Cnn_1N PF07989.11 CRK30234.1 - 0.00038 20.5 22.1 0.0077 16.4 5.9 3.2 1 1 1 2 2 2 2 Centrosomin N-terminal motif 1 Jnk-SapK_ap_N PF09744.9 CRK30234.1 - 0.0015 18.8 18.1 0.0015 18.8 18.1 2.2 1 1 1 2 2 2 1 JNK_SAPK-associated protein-1 KASH_CCD PF14662.6 CRK30234.1 - 0.021 14.6 25.2 0.029 14.2 22.5 2.1 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH ADIP PF11559.8 CRK30234.1 - 0.024 14.8 23.6 0.35 10.9 9.3 2.3 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding bZIP_1 PF00170.21 CRK30234.1 - 0.1 12.7 20.2 0.52 10.5 1.2 3.4 2 1 1 3 3 3 0 bZIP transcription factor FlaC_arch PF05377.11 CRK30234.1 - 0.11 12.9 11.9 7.5 7.0 0.8 3.9 1 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Uso1_p115_C PF04871.13 CRK30234.1 - 0.14 12.5 24.8 0.1 13.0 12.6 2.3 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region UPF0242 PF06785.11 CRK30234.1 - 0.23 11.5 27.3 0.91 9.6 12.3 2.5 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF4094 PF13334.6 CRK30234.1 - 0.26 11.7 11.7 0.049 14.1 5.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) Golgin_A5 PF09787.9 CRK30234.1 - 0.3 10.5 19.5 0.45 9.9 19.5 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 SHE3 PF17078.5 CRK30234.1 - 0.35 10.5 18.6 4.2 7.0 3.5 2.2 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 YabA PF06156.13 CRK30234.1 - 0.39 11.4 19.5 0.61 10.8 4.6 2.9 1 1 2 3 3 3 0 Initiation control protein YabA ATG16 PF08614.11 CRK30234.1 - 0.42 10.8 28.8 0.88 9.8 19.7 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF3450 PF11932.8 CRK30234.1 - 0.9 8.8 21.4 1.2 8.3 6.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) CENP-F_leu_zip PF10473.9 CRK30234.1 - 1 9.4 27.1 1.2 9.2 25.4 2.0 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HALZ PF02183.18 CRK30234.1 - 1.9 8.8 20.0 0.41 10.9 3.1 4.1 5 0 0 5 5 4 0 Homeobox associated leucine zipper DivIC PF04977.15 CRK30234.1 - 2.2 8.1 26.6 2.4 8.0 3.0 4.2 1 1 3 4 4 4 0 Septum formation initiator APG6_N PF17675.1 CRK30234.1 - 2.9 8.4 36.4 4.1 7.9 15.1 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF1664 PF07889.12 CRK30234.1 - 4.2 7.4 9.6 7.6 6.6 4.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 CRK30234.1 - 4.7 7.3 30.5 0.051 13.6 16.9 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein V_ATPase_I PF01496.19 CRK30234.1 - 5.3 4.8 16.3 0.2 9.5 9.5 1.8 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Mod_r PF07200.13 CRK30234.1 - 5.9 7.0 26.2 3.9 7.6 9.9 3.0 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein ZapB PF06005.12 CRK30234.1 - 8.4 6.9 31.7 26 5.3 10.5 3.8 1 1 2 3 3 3 0 Cell division protein ZapB Paralemmin PF03285.15 CRK30234.1 - 8.8 5.8 19.7 4.4 6.8 0.0 3.0 1 1 2 3 3 3 0 Paralemmin ISG65-75 PF11727.8 CRK30235.1 - 0.0052 16.1 0.8 0.0063 15.8 0.8 1.1 1 0 0 1 1 1 1 Invariant surface glycoprotein CENP-Q PF13094.6 CRK30235.1 - 0.025 14.8 4.2 0.032 14.5 4.2 1.1 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Med30 PF11315.8 CRK30235.1 - 0.028 14.6 0.1 0.037 14.2 0.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 30 GrpE PF01025.19 CRK30235.1 - 0.032 13.9 2.6 0.044 13.4 2.6 1.1 1 0 0 1 1 1 0 GrpE DUF1515 PF07439.11 CRK30235.1 - 0.094 12.7 0.1 0.19 11.8 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1515) FUSC PF04632.12 CRK30235.1 - 0.41 9.1 0.9 0.43 9.1 0.9 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family HEAT PF02985.22 CRK30236.1 - 0.0022 18.1 0.0 2.3 8.7 0.0 2.9 2 0 0 2 2 2 2 HEAT repeat Xpo1 PF08389.12 CRK30236.1 - 0.0073 16.4 0.3 2.1 8.4 0.0 3.5 2 1 1 3 3 3 1 Exportin 1-like protein Mce4_CUP1 PF11887.8 CRK30236.1 - 0.024 14.1 0.2 0.057 12.9 0.0 1.5 1 1 1 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative DUF4844 PF16133.5 CRK30236.1 - 0.17 12.4 0.6 26 5.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4844) 4HB PF17947.1 CRK30238.1 - 3.3e-30 104.0 0.3 6.9e-30 102.9 0.3 1.6 1 0 0 1 1 1 1 Four helical bundle domain ABC_tran PF00005.27 CRK30238.1 - 4.9e-08 33.6 0.0 1.6e-07 31.9 0.0 1.9 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 CRK30238.1 - 0.00017 21.5 0.0 0.00028 20.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CRK30238.1 - 0.00051 20.6 0.0 0.0016 19.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 CRK30238.1 - 0.00052 19.7 0.0 0.0018 18.0 0.0 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 CRK30238.1 - 0.0044 17.3 0.0 0.018 15.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 CRK30238.1 - 0.0077 16.6 0.0 0.62 10.5 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 CRK30238.1 - 0.011 15.5 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain SMC_N PF02463.19 CRK30238.1 - 0.017 14.6 0.0 0.029 13.8 0.0 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_27 PF13514.6 CRK30238.1 - 0.02 14.5 0.0 0.044 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CRK30238.1 - 0.029 14.9 0.0 0.093 13.3 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_33 PF13671.6 CRK30238.1 - 0.04 14.1 0.2 0.24 11.6 0.0 2.4 4 0 0 4 4 3 0 AAA domain MeaB PF03308.16 CRK30238.1 - 0.047 12.7 0.0 0.13 11.2 0.0 1.7 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NACHT PF05729.12 CRK30238.1 - 0.049 13.6 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 NACHT domain RsgA_GTPase PF03193.16 CRK30238.1 - 0.074 13.0 0.1 0.2 11.5 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase PRK PF00485.18 CRK30238.1 - 0.084 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family cobW PF02492.19 CRK30238.1 - 0.094 12.3 0.0 2.2 7.8 0.0 2.8 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 CRK30238.1 - 0.098 13.1 0.1 0.49 10.8 0.0 2.1 3 0 0 3 3 2 0 RNA helicase DUF1280 PF06918.14 CRK30238.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1280) AAA_16 PF13191.6 CRK30238.1 - 0.15 12.4 0.0 0.88 9.9 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain G-alpha PF00503.20 CRK30238.1 - 0.18 10.9 0.0 0.74 8.9 0.0 1.8 2 0 0 2 2 2 0 G-protein alpha subunit ParcG PF10274.9 CRK30238.1 - 0.2 11.8 0.3 6.3 6.9 0.1 2.1 1 1 0 2 2 2 0 Parkin co-regulated protein Sulfatase PF00884.23 CRK30248.1 - 1.9e-05 24.2 0.0 2.1e-05 24.1 0.0 1.0 1 0 0 1 1 1 1 Sulfatase Kinetochor_Ybp2 PF08568.10 CRK30250.1 - 7.8e-98 328.6 0.0 9.6e-98 328.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin Glyco_transf_28 PF03033.20 CRK30252.1 - 3.7e-19 69.1 0.1 2e-18 66.7 0.1 2.2 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 CRK30252.1 - 2.4e-07 29.9 0.0 5.3e-07 28.8 0.0 1.4 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.11 CRK30252.1 - 0.019 15.3 0.0 0.11 12.8 0.0 2.3 2 0 0 2 2 2 0 Autophagy-related protein C terminal domain TRIQK PF15168.6 CRK30252.1 - 0.03 14.2 0.9 1.5 8.8 2.0 2.6 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family Glyco_tran_28_C PF04101.16 CRK30252.1 - 0.062 13.3 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain LRR_1 PF00560.33 CRK30254.1 - 0.018 15.5 12.0 20 6.2 0.0 7.0 8 0 0 8 8 8 0 Leucine Rich Repeat DUF3678 PF12435.8 CRK30254.1 - 0.22 10.9 2.3 0.71 9.3 2.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) LRR_4 PF12799.7 CRK30254.1 - 2.7 8.6 11.9 5.1 7.7 0.3 4.6 4 2 0 4 4 4 0 Leucine Rich repeats (2 copies) CAP59_mtransfer PF11735.8 CRK30255.1 - 1.1e-64 218.4 0.0 1.5e-64 218.0 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 NAD_binding_1 PF00175.21 CRK30256.1 - 0.055 14.1 0.0 0.07 13.8 0.0 1.1 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain Sugar_tr PF00083.24 CRK30257.1 - 9.2e-55 186.3 7.5 9.7e-40 136.8 0.1 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter G-patch_2 PF12656.7 CRK30257.1 - 5.3e-14 52.0 1.5 1.8e-13 50.4 1.5 2.0 1 0 0 1 1 1 1 G-patch domain MFS_1 PF07690.16 CRK30257.1 - 1.8e-09 37.0 21.7 4.1e-09 35.8 21.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 CRK30258.1 - 9.3e-11 40.9 2.1 9.3e-11 40.9 2.1 1.7 1 1 0 1 1 1 1 MFS/sugar transport protein Fungal_trans_2 PF11951.8 CRK30259.1 - 5.6e-26 91.2 0.1 8.8e-14 51.1 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK30259.1 - 0.0035 17.4 17.4 0.0067 16.5 17.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MGC-24 PF05283.11 CRK30259.1 - 1.1 9.8 8.8 1.6 9.1 8.8 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Amino_oxidase PF01593.24 CRK30260.1 - 8.2e-54 183.6 0.1 9.6e-54 183.4 0.1 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CRK30260.1 - 1.2e-11 44.6 0.3 2.7e-11 43.5 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 CRK30260.1 - 1.7e-08 34.3 0.0 1.1e-07 31.6 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 CRK30260.1 - 4.9e-08 32.9 0.0 1.3e-06 28.2 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 CRK30260.1 - 1.5e-07 31.0 0.2 2.4e-07 30.3 0.2 1.2 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 CRK30260.1 - 3.7e-06 26.3 0.0 5.5e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 CRK30260.1 - 4.1e-06 26.1 0.8 7.1e-06 25.3 0.8 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 CRK30260.1 - 9.3e-06 25.1 0.0 2.3e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CRK30260.1 - 5.7e-05 22.0 0.0 0.00036 19.4 0.1 1.9 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 CRK30260.1 - 0.00029 20.2 0.0 0.11 11.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CRK30260.1 - 0.0016 17.6 0.0 0.0053 15.9 0.0 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.27 CRK30260.1 - 0.002 18.6 0.0 0.0076 16.8 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CRK30260.1 - 0.04 13.2 0.3 0.073 12.3 0.3 1.4 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.21 CRK30260.1 - 0.11 11.8 0.4 0.18 11.1 0.4 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain AA_permease_2 PF13520.6 CRK30261.1 - 1e-53 182.7 54.0 1.4e-53 182.3 54.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CRK30261.1 - 1.8e-27 96.1 46.9 2.3e-27 95.7 46.9 1.0 1 0 0 1 1 1 1 Amino acid permease Pox_EPC_I2-L1 PF12575.8 CRK30261.1 - 0.95 9.7 0.0 0.95 9.7 0.0 3.5 4 1 1 5 5 5 0 Poxvirus entry protein complex L1 and I2 DUF3043 PF11241.8 CRK30261.1 - 3.3 7.7 4.6 16 5.5 1.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) Na_H_Exchanger PF00999.21 CRK30262.1 - 8e-50 169.7 26.7 4.4e-49 167.3 26.7 1.7 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family Myb_DNA-bind_6 PF13921.6 CRK30263.1 - 6.3e-17 61.6 0.4 1.8e-16 60.1 0.4 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 CRK30263.1 - 3e-05 24.1 0.2 5.7e-05 23.2 0.2 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain MAPEG PF01124.18 CRK30265.1 - 1e-09 38.3 1.2 1.5e-09 37.9 1.2 1.2 1 0 0 1 1 1 1 MAPEG family BTP PF05232.12 CRK30265.1 - 0.059 13.4 0.7 0.1 12.7 0.7 1.3 1 0 0 1 1 1 0 Chlorhexidine efflux transporter Nnf1 PF03980.14 CRK30267.1 - 2.4e-32 111.6 0.3 4.5e-32 110.7 0.3 1.5 1 0 0 1 1 1 1 Nnf1 SlyX PF04102.12 CRK30267.1 - 1.3 9.7 6.1 4.6 7.9 1.9 2.9 2 1 0 2 2 2 0 SlyX PH_9 PF15410.6 CRK30268.1 - 7.5e-06 26.3 0.1 1.3e-05 25.5 0.1 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain NTF2 PF02136.20 CRK30269.1 - 4e-24 85.5 0.4 6.2e-24 84.9 0.4 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 CRK30269.1 - 4.5e-06 26.4 0.3 1.1e-05 25.1 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CRK30269.1 - 0.11 12.5 0.1 0.11 12.5 0.1 2.7 3 0 0 3 3 3 0 RNA binding motif GRP PF07172.11 CRK30269.1 - 6.2 7.6 16.8 27 5.5 16.8 2.2 1 0 0 1 1 1 0 Glycine rich protein family Phosphodiest PF01663.22 CRK30270.1 - 2.2e-14 53.8 0.2 4.4e-14 52.8 0.2 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 CRK30270.1 - 6.3e-05 22.5 0.3 0.00026 20.5 0.4 1.8 2 0 0 2 2 2 1 Metalloenzyme superfamily Sulfatase PF00884.23 CRK30270.1 - 0.00053 19.5 0.1 0.0015 18.0 0.1 1.8 2 0 0 2 2 2 1 Sulfatase RIC3 PF15361.6 CRK30270.1 - 0.13 12.6 0.0 0.25 11.7 0.0 1.4 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 DUF4079 PF13301.6 CRK30271.1 - 0.0041 17.3 8.8 0.0087 16.2 3.4 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF4079) Ni_hydr_CYTB PF01292.20 CRK30271.1 - 0.085 12.4 5.4 0.15 11.6 5.4 1.4 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 DUF998 PF06197.13 CRK30271.1 - 0.14 11.8 9.0 0.07 12.7 6.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF998) Cytochrom_B561 PF03188.16 CRK30271.1 - 0.35 11.0 8.4 1.1 9.4 8.4 1.7 1 1 0 1 1 1 0 Eukaryotic cytochrome b561 FixS PF03597.15 CRK30272.1 - 0.029 14.1 0.8 0.029 14.1 0.8 2.0 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type Corona_nucleoca PF00937.18 CRK30272.1 - 0.057 12.5 4.5 0.088 11.8 4.5 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DUF1509 PF07420.11 CRK30272.1 - 0.54 9.2 6.5 1.1 8.1 6.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) NTF2 PF02136.20 CRK30273.1 - 1.3e-23 83.8 0.4 2.6e-23 82.8 0.4 1.5 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Phosphodiest PF01663.22 CRK30273.1 - 2.2e-14 53.8 0.3 6.4e-14 52.3 0.3 1.7 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase RRM_1 PF00076.22 CRK30273.1 - 1.6e-05 24.6 0.0 4e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Metalloenzyme PF01676.18 CRK30273.1 - 9.6e-05 21.9 0.3 0.00035 20.0 0.4 1.8 2 0 0 2 2 2 1 Metalloenzyme superfamily Sulfatase PF00884.23 CRK30273.1 - 0.0014 18.0 0.1 0.0033 16.9 0.1 1.6 1 0 0 1 1 1 1 Sulfatase Cellulase PF00150.18 CRK30275.1 - 1.8e-14 53.8 0.0 3.6e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CTP_transf_like PF01467.26 CRK30275.1 - 2.4e-06 27.8 0.0 4e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like EF-hand_4 PF12763.7 CRK30276.1 - 1.8e-08 34.3 0.0 3.1e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand TFIIA PF03153.13 CRK30276.1 - 0.0049 16.9 36.8 0.0076 16.3 36.8 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SKA1 PF07160.12 CRK30276.1 - 5 6.9 9.4 9.1 6.1 9.4 1.4 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 EF-hand_4 PF12763.7 CRK30277.1 - 5.5e-31 106.6 0.0 6e-14 51.9 0.0 2.6 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand E3_binding PF02817.17 CRK30277.1 - 6.4e-06 26.4 0.7 0.22 11.9 0.1 2.8 2 0 0 2 2 2 2 e3 binding domain DUF1720 PF08226.11 CRK30277.1 - 0.00017 21.9 243.7 0.016 15.6 20.2 10.5 5 3 3 8 8 8 4 Domain of unknown function (DUF1720) TFIIA PF03153.13 CRK30277.1 - 0.0038 17.3 37.8 0.0038 17.3 37.8 6.8 3 3 3 6 6 6 1 Transcription factor IIA, alpha/beta subunit EF-hand_1 PF00036.32 CRK30277.1 - 0.033 13.7 0.1 12 5.7 0.0 2.5 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.6 CRK30277.1 - 0.064 13.2 0.6 37 4.6 0.0 3.5 4 0 0 4 4 4 0 EF-hand domain EF-hand_7 PF13499.6 CRK30277.1 - 0.074 13.5 9.1 2.3 8.7 0.0 3.9 4 0 0 4 4 4 0 EF-hand domain pair Forkhead PF00250.18 CRK30279.1 - 1.3e-70 233.7 0.5 7.3e-34 115.9 0.1 2.4 2 0 0 2 2 2 2 Forkhead domain ATG101 PF07855.12 CRK30280.1 - 4.5e-25 88.4 0.3 5.2e-25 88.2 0.3 1.0 1 0 0 1 1 1 1 Autophagy-related protein 101 ATG101 PF07855.12 CRK30282.1 - 1.1e-46 158.7 0.2 2e-46 157.8 0.2 1.4 1 0 0 1 1 1 1 Autophagy-related protein 101 WHIM1 PF15612.6 CRK30282.1 - 0.00085 18.8 0.0 0.002 17.6 0.0 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 DUF1770 PF08589.10 CRK30283.1 - 1.5e-36 125.3 0.4 1.9e-36 125.0 0.4 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) WHIM1 PF15612.6 CRK30284.1 - 0.0015 18.0 0.0 0.003 17.0 0.0 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 DBINO PF13892.6 CRK30284.1 - 0.08 13.3 0.8 0.16 12.3 0.8 1.5 1 0 0 1 1 1 0 DNA-binding domain Ribosomal_L2_C PF03947.18 CRK30285.1 - 3.1e-43 147.0 3.6 5.3e-43 146.2 3.6 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 CRK30285.1 - 3.7e-15 55.6 0.1 8.5e-15 54.5 0.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain PfkB PF00294.24 CRK30287.1 - 1.7e-30 106.4 0.0 2.1e-30 106.1 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase EST1_DNA_bind PF10373.9 CRK30288.1 - 1.3e-65 221.7 0.0 3.1e-65 220.5 0.0 1.7 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain EST1 PF10374.9 CRK30288.1 - 1.9e-19 70.7 0.2 1.9e-19 70.7 0.2 2.2 2 0 0 2 2 2 1 Telomerase activating protein Est1 Complex1_LYR_2 PF13233.6 CRK30289.1 - 1.1e-12 48.5 1.1 6.8e-05 23.5 0.1 2.5 2 0 0 2 2 2 2 Complex1_LYR-like Complex1_LYR PF05347.15 CRK30289.1 - 9.5e-06 25.6 9.6 0.013 15.5 0.2 3.1 4 0 0 4 4 2 2 Complex 1 protein (LYR family) RMMBL PF07521.12 CRK30289.1 - 1.3e-05 25.1 0.1 0.29 11.1 0.0 2.6 2 0 0 2 2 2 2 Zn-dependent metallo-hydrolase RNA specificity domain Ricin_B_lectin PF00652.22 CRK30289.1 - 0.0086 16.3 0.7 6.2 7.1 0.0 2.5 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain Nre_C PF04895.12 CRK30289.1 - 0.022 14.7 1.4 7 6.6 0.1 2.4 2 0 0 2 2 2 0 Archaeal Nre, C-terminal XPA_N PF01286.18 CRK30289.1 - 0.032 14.3 0.9 0.39 10.8 0.1 3.0 4 0 0 4 4 2 0 XPA protein N-terminal DUF5414 PF17435.2 CRK30289.1 - 0.079 12.6 0.0 19 4.9 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5414) WbqC PF08889.11 CRK30289.1 - 0.083 12.8 0.0 17 5.2 0.0 2.4 2 0 0 2 2 2 0 WbqC-like protein family zf-trcl PF13451.6 CRK30289.1 - 0.24 11.3 3.3 16 5.5 0.2 2.7 2 0 0 2 2 2 0 Probable zinc-ribbon domain zf-C2H2_11 PF16622.5 CRK30289.1 - 0.25 11.1 10.7 3.3 7.6 1.8 2.8 2 0 0 2 2 2 0 zinc-finger C2H2-type eIF-1a PF01176.19 CRK30289.1 - 0.44 10.4 1.3 13 5.7 0.1 2.5 2 0 0 2 2 2 0 Translation initiation factor 1A / IF-1 Ephrin_rec_like PF07699.13 CRK30289.1 - 0.56 10.0 3.3 19 5.1 0.3 2.5 2 0 0 2 2 2 0 Putative ephrin-receptor like zf-C2H2_jaz PF12171.8 CRK30289.1 - 0.95 9.8 11.5 3.4 8.1 0.1 3.9 4 0 0 4 4 2 0 Zinc-finger double-stranded RNA-binding G10 PF01125.17 CRK30290.1 - 2.4e-62 209.1 4.1 2.6e-62 208.9 4.1 1.0 1 0 0 1 1 1 1 G10 protein RNA_pol_L_2 PF13656.6 CRK30291.1 - 1e-29 102.1 0.0 1.3e-29 101.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 CRK30291.1 - 2.4e-11 42.9 0.0 3.2e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF3306 PF11748.8 CRK30292.1 - 0.12 13.3 11.0 0.15 13.0 11.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Neur_chan_memb PF02932.16 CRK30292.1 - 2.8 7.9 5.8 3.4 7.7 5.8 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF908 PF06012.12 CRK30292.1 - 7.6 5.8 8.0 8.4 5.7 8.0 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) G10 PF01125.17 CRK30293.1 - 1.6e-62 209.6 3.8 1.7e-62 209.5 3.8 1.0 1 0 0 1 1 1 1 G10 protein nos_propeller PF18764.1 CRK30293.1 - 0.17 11.8 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Nitrous oxide reductase propeller repeat RNA_pol_L_2 PF13656.6 CRK30294.1 - 1e-29 102.1 0.0 1.3e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 CRK30294.1 - 2.3e-11 42.9 0.0 3.2e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Pkinase PF00069.25 CRK30296.1 - 1.8e-49 168.5 0.0 2.7e-49 167.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK30296.1 - 2.2e-27 96.0 0.0 3e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CRK30296.1 - 0.00073 18.9 0.0 0.0014 18.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CRK30296.1 - 0.028 13.8 0.0 0.047 13.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CRK30296.1 - 0.039 13.9 0.2 0.5 10.2 0.0 2.5 2 1 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 CRK30296.1 - 0.15 11.6 0.0 0.35 10.4 0.0 1.5 2 0 0 2 2 2 0 RIO1 family Hamartin PF04388.12 CRK30296.1 - 0.2 10.3 7.6 0.23 10.1 7.6 1.1 1 0 0 1 1 1 0 Hamartin protein Pkinase PF00069.25 CRK30297.1 - 1.3e-55 188.6 0.0 1.7e-50 171.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CRK30297.1 - 2.1e-32 112.4 0.0 2.9e-31 108.7 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CRK30297.1 - 1.7e-06 27.6 0.0 2.8e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CRK30297.1 - 4.9e-05 23.4 0.3 0.00015 21.8 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CRK30297.1 - 0.0025 16.7 0.0 0.0041 16.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Sybindin PF04099.12 CRK30298.1 - 2.2e-23 82.8 0.0 3.2e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 Sybindin-like family CCDC117 PF15810.5 CRK30298.1 - 0.12 12.7 0.5 0.16 12.3 0.5 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 117 SUIM_assoc PF16619.5 CRK30298.1 - 0.25 11.4 12.8 0.48 10.5 12.8 1.4 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Peroxin-3 PF04882.12 CRK30299.1 - 2.6e-117 392.7 0.0 2.9e-117 392.5 0.0 1.0 1 0 0 1 1 1 1 Peroxin-3 Sybindin PF04099.12 CRK30300.1 - 4.3e-18 65.6 0.0 5e-18 65.4 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Peroxin-3 PF04882.12 CRK30301.1 - 1.3e-115 387.2 0.0 1.6e-115 386.8 0.0 1.0 1 0 0 1 1 1 1 Peroxin-3 Med3 PF11593.8 CRK30301.1 - 1.6 7.8 4.7 2.7 7.1 4.7 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal eRF1_1 PF03463.15 CRK30302.1 - 6.3e-21 74.7 0.0 1.2e-20 73.8 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 1 TPR_1 PF00515.28 CRK30302.1 - 2.5e-20 71.4 7.3 3e-05 23.7 0.1 6.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 CRK30302.1 - 4.7e-20 70.0 6.6 0.00067 19.6 0.2 6.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 CRK30302.1 - 4.8e-18 63.8 9.4 0.0031 17.6 0.1 6.3 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_7 PF13176.6 CRK30302.1 - 5.1e-16 57.4 9.6 0.0017 18.2 0.0 6.0 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 CRK30302.1 - 1.5e-13 50.8 13.6 6.9e-06 26.3 0.2 5.9 3 3 3 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 CRK30302.1 - 1.3e-11 44.0 0.9 0.056 13.8 0.1 6.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_10 PF13374.6 CRK30302.1 - 1.5e-11 43.8 3.9 0.0011 18.8 0.1 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 CRK30302.1 - 3.1e-11 43.1 11.0 0.00033 21.2 0.0 6.4 6 2 0 6 6 5 3 Tetratricopeptide repeat eRF1_2 PF03464.15 CRK30302.1 - 9.5e-09 35.7 0.0 2.2e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 2 TPR_16 PF13432.6 CRK30302.1 - 4.1e-08 33.7 12.7 0.0025 18.4 0.1 5.5 6 1 0 6 6 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 CRK30302.1 - 1.1e-06 29.1 18.0 0.021 15.3 0.0 6.5 5 2 1 7 7 6 3 Tetratricopeptide repeat TPR_6 PF13174.6 CRK30302.1 - 4.3e-06 27.0 14.2 0.0038 17.8 0.0 6.7 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 CRK30302.1 - 1.1e-05 25.0 11.8 0.056 13.1 0.3 5.3 4 1 1 5 5 5 3 TPR repeat SNAP PF14938.6 CRK30302.1 - 0.00089 18.8 5.8 0.068 12.6 1.5 3.6 2 2 0 2 2 2 1 Soluble NSF attachment protein, SNAP TPR_15 PF13429.6 CRK30302.1 - 0.00096 18.4 2.5 0.065 12.4 0.1 3.3 2 2 0 2 2 2 1 Tetratricopeptide repeat DUF4810 PF16068.5 CRK30302.1 - 0.0058 17.1 0.0 21 5.8 0.0 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4810) TPR_9 PF13371.6 CRK30302.1 - 0.012 15.8 0.6 2.1 8.6 0.0 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_21 PF09976.9 CRK30302.1 - 0.021 14.5 8.2 0.1 12.3 1.5 3.2 1 1 2 3 3 3 0 Tetratricopeptide repeat-like domain MIT PF04212.18 CRK30302.1 - 0.056 13.5 9.9 3.7 7.7 0.1 5.0 3 2 3 6 6 5 0 MIT (microtubule interacting and transport) domain TOM20_plant PF06552.12 CRK30302.1 - 0.062 13.1 0.2 0.51 10.1 0.0 2.6 3 0 0 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 RPN7 PF10602.9 CRK30302.1 - 0.17 11.6 3.1 81 2.9 0.0 4.2 3 2 2 5 5 5 0 26S proteasome subunit RPN7 DUF2225 PF09986.9 CRK30302.1 - 0.28 10.9 4.4 10 5.7 0.3 3.6 2 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) PPR PF01535.20 CRK30302.1 - 0.33 11.3 4.1 2.1 8.8 0.1 3.9 4 0 0 4 4 3 0 PPR repeat ANAPC3 PF12895.7 CRK30302.1 - 1.2 9.4 9.2 1.1 9.5 0.6 3.7 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 CRK30304.1 - 1e-14 53.3 9.1 0.01 15.9 0.0 7.7 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 CRK30304.1 - 7.4e-14 50.9 2.3 0.047 13.5 0.0 6.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 CRK30304.1 - 5.4e-10 39.6 5.9 0.13 12.8 0.2 5.9 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 CRK30304.1 - 6.6e-07 29.6 17.1 0.6 11.1 0.0 8.6 6 3 3 9 9 9 2 Tetratricopeptide repeat TPR_12 PF13424.6 CRK30304.1 - 7.4e-07 29.4 7.9 0.33 11.3 0.1 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 CRK30304.1 - 8.7e-07 28.7 3.8 5.3 7.5 0.0 7.3 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_6 PF13174.6 CRK30304.1 - 5.8e-06 26.6 6.8 5.6 7.8 0.1 7.7 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_11 PF13414.6 CRK30304.1 - 0.00025 20.7 0.0 0.058 13.1 0.0 4.3 5 0 0 5 5 5 1 TPR repeat TPR_7 PF13176.6 CRK30304.1 - 0.0003 20.6 2.5 3.8 7.8 0.4 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 CRK30304.1 - 0.00088 19.9 0.0 0.075 13.7 0.0 6.5 6 2 2 8 8 8 2 Tetratricopeptide repeat TPR_10 PF13374.6 CRK30304.1 - 0.023 14.6 1.2 14 5.8 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 CRK30304.1 - 0.024 15.0 1.0 13 6.4 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_3 PF07720.12 CRK30304.1 - 0.11 12.5 0.1 0.46 10.5 0.1 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat Alpha-amylase PF00128.24 CRK30305.1 - 5.2e-109 364.9 0.0 5.9e-109 364.7 0.0 1.0 1 0 0 1 1 1 1 Alpha amylase, catalytic domain TetR_C_31 PF17940.1 CRK30305.1 - 0.08 13.2 0.2 2.6 8.3 0.0 3.0 3 1 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain CMAS PF02353.20 CRK30306.1 - 7.8e-13 48.3 0.0 1.1e-12 47.8 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MaoC_dehydratas PF01575.19 CRK30307.1 - 0.00012 21.7 0.0 0.00018 21.1 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain Malt_amylase_C PF16657.5 CRK30308.1 - 0.0016 18.6 0.0 0.0019 18.3 0.0 1.2 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain Alpha-amylase_C PF02806.18 CRK30308.1 - 0.0062 17.0 0.0 0.0076 16.7 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain DUF3459 PF11941.8 CRK30308.1 - 0.017 15.4 0.3 0.025 14.9 0.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3459) CMAS PF02353.20 CRK30309.1 - 9.4e-37 126.8 0.0 1.1e-36 126.5 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 CRK30309.1 - 8.8e-07 29.6 0.0 1.5e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CRK30309.1 - 2.9e-06 27.8 0.0 5e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CRK30309.1 - 3.5e-05 23.7 0.0 5.7e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain UFD1 PF03152.14 CRK30310.1 - 1.6e-26 92.9 0.0 3.6e-13 49.3 0.0 3.4 4 0 0 4 4 4 3 Ubiquitin fusion degradation protein UFD1 AZUL PF16558.5 CRK30310.1 - 2e-06 27.9 0.2 2e-06 27.9 0.2 2.6 2 1 1 3 3 3 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A zf-RING_7 PF02591.15 CRK30310.1 - 0.034 14.3 1.4 0.034 14.3 1.4 3.0 3 1 0 3 3 3 0 C4-type zinc ribbon domain KIF1B PF12423.8 CRK30310.1 - 0.77 10.2 2.8 0.48 10.9 0.2 2.0 2 0 0 2 2 2 0 Kinesin protein 1B Zn_Tnp_IS91 PF14319.6 CRK30311.1 - 0.32 11.1 4.1 0.82 9.8 4.1 1.6 1 0 0 1 1 1 0 Transposase zinc-binding domain Actin PF00022.19 CRK30312.1 - 1.2e-99 333.7 0.0 1.1e-98 330.6 0.0 1.9 1 1 0 1 1 1 1 Actin CDH-cyt PF16010.5 CRK30313.1 - 1.3e-47 161.9 0.5 1.3e-47 161.9 0.5 1.7 2 0 0 2 2 2 1 Cytochrome domain of cellobiose dehydrogenase PD40 PF07676.12 CRK30313.1 - 0.025 14.5 0.0 0.074 13.0 0.0 1.8 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat 2C_adapt PF08793.10 CRK30313.1 - 0.054 13.7 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 2-cysteine adaptor domain Aldo_ket_red PF00248.21 CRK30314.1 - 1.6e-48 165.4 0.0 2.1e-48 165.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Peptidase_S49_N PF08496.10 CRK30315.1 - 0.28 11.2 8.5 0.28 11.2 2.5 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal PRC2_HTH_1 PF18118.1 CRK30315.1 - 3 8.7 7.8 0.88 10.4 1.2 2.6 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain zf-C3HC4_3 PF13920.6 CRK30315.1 - 3.6 7.5 7.4 4.6 7.2 3.3 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) BRF1 PF07741.13 CRK30315.1 - 6.8 7.1 15.5 2 8.8 6.2 2.8 2 0 0 2 2 2 0 Brf1-like TBP-binding domain DUF3915 PF13054.6 CRK30315.1 - 8.2 6.4 8.1 19 5.2 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) Sugar_tr PF00083.24 CRK30316.1 - 2.5e-91 306.8 20.4 3.1e-91 306.5 20.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK30316.1 - 7.4e-22 77.7 40.6 2.9e-16 59.4 19.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-C2H2 PF00096.26 CRK30317.1 - 0.0056 17.1 1.7 0.033 14.7 0.2 2.9 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CRK30317.1 - 0.35 11.8 5.6 0.4 11.6 0.1 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger RhgB_N PF09284.10 CRK30318.1 - 2.2e-107 358.3 3.8 3.1e-107 357.8 3.8 1.2 1 0 0 1 1 1 1 Rhamnogalacturonan lyase B, N-terminal CBM-like PF14683.6 CRK30318.1 - 8.2e-38 129.9 0.2 2.6e-37 128.2 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 CRK30318.1 - 6.7e-22 77.1 5.3 2.1e-21 75.5 5.3 2.0 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II Zn_clus PF00172.18 CRK30318.1 - 6.1e-07 29.5 8.7 1.1e-06 28.6 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 CRK30318.1 - 1.1e-05 24.5 0.0 0.0055 15.6 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain CarboxypepD_reg PF13620.6 CRK30318.1 - 1.5e-05 25.2 3.6 8.8e-05 22.7 3.6 2.4 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 CRK30318.1 - 0.013 15.5 0.2 0.035 14.1 0.2 1.7 1 0 0 1 1 1 0 CarboxypepD_reg-like domain FAT PF02259.23 CRK30319.1 - 2.4e-131 438.1 10.4 5.2e-131 437.0 10.4 1.6 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 CRK30319.1 - 2.4e-73 247.0 0.1 4.2e-73 246.2 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 CRK30319.1 - 3.8e-70 235.0 5.2 2.9e-67 225.6 0.3 5.0 5 0 0 5 5 5 1 Domain of unknown function (DUF3385) FRB_dom PF08771.11 CRK30319.1 - 5.5e-46 155.0 2.2 1.9e-45 153.3 0.2 3.2 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain HEAT PF02985.22 CRK30319.1 - 2.2e-14 52.3 15.3 0.00035 20.6 0.0 11.4 11 0 0 11 11 11 2 HEAT repeat FATC PF02260.20 CRK30319.1 - 9.9e-14 50.9 0.1 3e-13 49.3 0.1 1.9 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.6 CRK30319.1 - 1.1e-13 51.3 14.9 8.4e-05 22.9 0.1 8.4 8 2 1 9 9 9 3 HEAT repeats HEAT_EZ PF13513.6 CRK30319.1 - 4.3e-12 46.2 11.4 2.8e-05 24.5 0.1 9.9 8 3 3 11 11 10 2 HEAT-like repeat Cnd1 PF12717.7 CRK30319.1 - 2.6e-06 27.6 0.4 0.15 12.1 0.0 5.8 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 CRK30319.1 - 5.5e-05 21.9 3.6 2.4 6.6 0.0 5.1 3 2 2 5 5 5 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 CRK30319.1 - 0.00023 21.7 0.7 1.3e+02 3.2 0.0 6.9 7 1 1 8 8 7 0 Vacuolar 14 Fab1-binding region PRKCSH-like PF12999.7 CRK30320.1 - 1.5e-40 138.9 13.5 8.2e-25 87.6 1.4 3.3 3 1 1 4 4 3 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 CRK30320.1 - 1e-31 109.7 0.6 1e-31 109.7 0.6 1.8 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 CRK30320.1 - 8.2e-10 39.6 0.9 3.4e-09 37.6 0.9 2.2 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein ATG27 PF09451.10 CRK30320.1 - 0.0047 16.8 0.7 0.01 15.7 0.7 1.5 1 0 0 1 1 1 1 Autophagy-related protein 27 Ish1 PF10281.9 CRK30320.1 - 0.035 14.4 0.0 0.14 12.5 0.0 2.1 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein Snapin_Pallidin PF14712.6 CRK30320.1 - 0.041 14.3 0.1 0.041 14.3 0.1 2.5 3 0 0 3 3 3 0 Snapin/Pallidin DUF728 PF05304.12 CRK30320.1 - 0.055 13.3 1.6 0.58 10.0 1.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF728) CdAMP_rec PF06153.11 CRK30320.1 - 0.058 13.6 0.7 1.7 8.9 0.1 2.7 2 1 1 3 3 3 0 Cyclic-di-AMP receptor DUF1664 PF07889.12 CRK30320.1 - 0.16 12.0 1.6 1.3 9.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF2721 PF11026.8 CRK30320.1 - 0.28 11.1 3.3 0.3 11.0 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Fib_alpha PF08702.10 CRK30320.1 - 0.32 11.2 2.9 1.3 9.2 0.1 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Filament PF00038.21 CRK30320.1 - 0.41 10.2 19.2 0.54 9.8 7.9 2.4 3 0 0 3 3 3 0 Intermediate filament protein CCCAP PF15964.5 CRK30320.1 - 0.46 8.7 11.7 0.089 11.1 7.5 1.8 2 0 0 2 2 2 0 Centrosomal colon cancer autoantigen protein family Mei5 PF10376.9 CRK30320.1 - 0.74 9.6 12.8 0.48 10.3 0.6 2.5 2 0 0 2 2 2 0 Double-strand recombination repair protein Mod_r PF07200.13 CRK30320.1 - 0.85 9.7 14.6 0.17 12.0 0.6 3.2 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein GTP-bdg_M PF16360.5 CRK30320.1 - 0.93 10.1 13.9 0.043 14.4 4.3 2.9 1 1 1 2 2 2 0 GTP-binding GTPase Middle Region Prefoldin_2 PF01920.20 CRK30320.1 - 1.9 8.5 20.2 0.96 9.4 3.1 4.0 3 1 1 4 4 4 0 Prefoldin subunit YabA PF06156.13 CRK30320.1 - 2.3 8.9 8.8 4 8.1 0.1 2.8 3 0 0 3 3 2 0 Initiation control protein YabA H-kinase_dim PF02895.14 CRK30320.1 - 4.8 7.7 5.4 11 6.5 0.2 2.9 3 0 0 3 3 3 0 Signal transducing histidine kinase, homodimeric domain Med30 PF11315.8 CRK30320.1 - 6.3 7.0 8.5 12 6.1 1.2 3.1 3 0 0 3 3 3 0 Mediator complex subunit 30 Peptidase_M28 PF04389.17 CRK30321.1 - 9.6e-27 94.0 0.4 1.2e-25 90.3 0.4 2.1 1 1 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 CRK30321.1 - 6.8e-06 25.9 0.2 1.7e-05 24.6 0.2 1.7 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.15 CRK30321.1 - 0.023 14.2 0.0 0.071 12.6 0.0 1.8 2 0 0 2 2 2 0 Nicastrin FAD_binding_3 PF01494.19 CRK30322.1 - 4.2e-31 108.5 0.2 5.5e-31 108.1 0.2 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 CRK30322.1 - 9.4e-12 45.2 1.1 2.1e-05 24.3 0.1 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CRK30322.1 - 2e-09 37.1 0.3 0.0018 17.5 0.0 2.3 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CRK30322.1 - 8.4e-07 29.5 0.3 0.00066 20.2 0.1 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 CRK30322.1 - 1.4e-05 24.2 2.7 0.0082 15.0 0.2 2.9 2 1 1 3 3 3 2 Tryptophan halogenase NAD_binding_8 PF13450.6 CRK30322.1 - 0.00011 22.4 0.1 0.00033 20.8 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 CRK30322.1 - 0.00092 18.6 0.0 0.003 16.9 0.0 1.7 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 CRK30322.1 - 0.00099 17.9 0.1 0.59 8.8 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein AlaDh_PNT_C PF01262.21 CRK30322.1 - 0.0034 16.7 0.2 0.0048 16.2 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 CRK30322.1 - 0.0035 16.5 0.1 0.01 15.0 0.0 1.7 1 1 1 2 2 2 1 FAD binding domain GIDA PF01134.22 CRK30322.1 - 0.0053 15.9 0.1 0.0071 15.5 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 CRK30322.1 - 0.011 15.0 0.0 1.2 8.3 0.0 2.3 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 CRK30322.1 - 0.013 15.1 0.1 0.025 14.2 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 CRK30322.1 - 0.076 13.0 0.0 0.2 11.6 0.0 1.7 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus SE PF08491.10 CRK30322.1 - 0.14 11.2 0.0 0.35 9.9 0.0 1.6 2 0 0 2 2 2 0 Squalene epoxidase Sugar_tr PF00083.24 CRK30323.1 - 1.1e-122 410.2 20.1 1.2e-122 410.0 20.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK30323.1 - 5.1e-19 68.4 32.6 5.1e-19 68.4 32.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.9 CRK30323.1 - 2.8 8.3 6.6 1.3 9.3 0.8 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) Pyr_redox_2 PF07992.14 CRK30324.1 - 0.00084 18.7 0.0 0.00099 18.4 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CRK30324.1 - 0.0016 18.1 0.1 0.0021 17.7 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 CRK30324.1 - 0.0022 18.0 0.0 0.0039 17.2 0.0 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding MCRA PF06100.11 CRK30324.1 - 0.0082 15.0 0.0 0.0098 14.7 0.0 1.1 1 0 0 1 1 1 1 MCRA family Lycopene_cycl PF05834.12 CRK30324.1 - 0.023 13.8 0.0 0.03 13.4 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein ThiF PF00899.21 CRK30324.1 - 0.039 13.3 0.0 0.043 13.2 0.0 1.1 1 0 0 1 1 1 0 ThiF family NAD_binding_8 PF13450.6 CRK30324.1 - 0.046 13.9 0.6 0.076 13.2 0.0 1.7 2 0 0 2 2 1 0 NAD(P)-binding Rossmann-like domain Sacchrp_dh_NADP PF03435.18 CRK30324.1 - 0.047 14.0 0.0 0.073 13.3 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Malic_M PF03949.15 CRK30324.1 - 0.055 12.7 0.1 0.059 12.6 0.1 1.1 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain FAD_binding_3 PF01494.19 CRK30324.1 - 0.073 12.3 0.0 0.093 12.0 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain F420_oxidored PF03807.17 CRK30324.1 - 0.11 13.1 0.0 0.2 12.3 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent K_oxygenase PF13434.6 CRK30324.1 - 0.18 10.9 0.0 0.2 10.8 0.0 1.1 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Ribonuc_L-PSP PF01042.21 CRK30325.1 - 1.5e-16 60.5 0.0 1.7e-16 60.3 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Methyltransf_23 PF13489.6 CRK30327.1 - 3.6e-21 75.7 0.0 6.1e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK30327.1 - 7.9e-13 48.5 0.0 1.1e-11 44.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK30327.1 - 5.7e-11 43.0 0.0 1.5e-10 41.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CRK30327.1 - 7.4e-09 36.2 0.0 1.6e-08 35.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK30327.1 - 1.3e-07 32.3 0.0 1e-06 29.4 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain CheR PF01739.18 CRK30327.1 - 0.0013 18.3 0.0 0.0056 16.2 0.0 1.9 2 0 0 2 2 2 1 CheR methyltransferase, SAM binding domain MTS PF05175.14 CRK30327.1 - 0.0035 16.9 0.0 0.0081 15.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 CRK30327.1 - 0.008 15.7 0.0 0.019 14.5 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.19 CRK30327.1 - 0.015 15.4 0.0 0.024 14.8 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase PrmA PF06325.13 CRK30327.1 - 0.052 12.9 0.0 0.079 12.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 CRK30327.1 - 0.16 11.7 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Fasciclin PF02469.22 CRK30328.1 - 1.1e-14 54.8 0.7 2.1e-13 50.6 0.7 2.1 1 1 0 1 1 1 1 Fasciclin domain Melibiase_2 PF16499.5 CRK30329.1 - 2.3e-55 187.8 5.2 5.8e-55 186.5 5.2 1.7 1 1 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 CRK30329.1 - 1.1e-10 41.4 0.2 2.2e-10 40.5 0.2 1.6 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 CRK30329.1 - 1.6e-09 37.2 0.0 2.8e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Melibiase Raffinose_syn PF05691.12 CRK30329.1 - 0.00034 18.5 0.1 0.00053 17.9 0.1 1.2 1 0 0 1 1 1 1 Raffinose synthase or seed imbibition protein Sip1 Glyco_hydro_61 PF03443.14 CRK30330.1 - 1.6e-50 171.9 0.1 1.8e-50 171.7 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Alginate_lyase PF05426.12 CRK30331.1 - 3.4e-07 30.1 7.8 7.6e-07 29.0 7.8 1.5 1 1 0 1 1 1 1 Alginate lyase Alginate_lyase PF05426.12 CRK30332.1 - 9.9e-09 35.1 3.0 2e-08 34.2 3.0 1.4 1 1 0 1 1 1 1 Alginate lyase Pept_tRNA_hydro PF01195.19 CRK30334.1 - 9.3e-26 90.8 0.0 1.2e-25 90.5 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase Radical_SAM_C PF16199.5 CRK30335.1 - 6.5e-33 112.6 0.0 1.2e-32 111.7 0.0 1.5 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 CRK30335.1 - 2.6e-15 57.2 0.1 1.1e-14 55.2 0.0 2.0 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 CRK30335.1 - 1.5e-08 34.8 0.0 2.9e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CRK30335.1 - 1.9e-05 24.6 0.0 4.2e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CRK30335.1 - 0.051 14.0 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain BAR PF03114.18 CRK30337.1 - 5.9e-66 222.5 3.0 4.1e-65 219.8 4.1 1.8 2 0 0 2 2 2 1 BAR domain RTA1 PF04479.13 CRK30337.1 - 3.4e-31 108.5 9.5 5e-31 107.9 9.5 1.2 1 0 0 1 1 1 1 RTA1 like protein AAA PF00004.29 CRK30337.1 - 5.9e-20 72.0 0.5 6.1e-19 68.8 0.5 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 CRK30337.1 - 4.1e-11 42.7 0.3 9.2e-11 41.5 0.3 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 CRK30337.1 - 2.1e-10 40.2 0.7 5e-10 39.0 0.7 1.7 1 0 0 1 1 1 1 AAA+ lid domain Zn_clus PF00172.18 CRK30337.1 - 4e-07 30.1 13.5 7.6e-07 29.2 13.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA_2 PF07724.14 CRK30337.1 - 0.0098 16.0 0.1 0.033 14.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) Prot_ATP_OB_N PF17758.1 CRK30337.1 - 0.011 15.4 0.7 0.024 14.2 0.0 2.0 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain Fungal_trans PF04082.18 CRK30337.1 - 0.062 12.3 0.0 0.14 11.1 0.0 1.5 1 0 0 1 1 1 0 Fungal specific transcription factor domain DCP1 PF06058.13 CRK30338.1 - 5.2e-27 94.1 0.0 7.4e-27 93.6 0.0 1.2 1 0 0 1 1 1 1 Dcp1-like decapping family DUF2288 PF10052.9 CRK30338.1 - 0.14 12.2 0.1 0.25 11.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2288) Exo_endo_phos PF03372.23 CRK30339.1 - 2e-06 27.5 0.0 6.9e-06 25.7 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Rrp15p PF07890.12 CRK30339.1 - 0.85 10.0 7.0 3.2 8.1 1.4 2.6 2 0 0 2 2 2 0 Rrp15p Glyco_hydro_10 PF00331.20 CRK30340.1 - 2e-106 355.7 0.1 2.3e-106 355.5 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Glyco_hydro_1 PF00232.18 CRK30340.1 - 0.034 12.6 0.1 0.066 11.6 0.1 1.4 2 0 0 2 2 2 0 Glycosyl hydrolase family 1 GYF_2 PF14237.6 CRK30340.1 - 0.2 11.5 0.4 0.47 10.3 0.4 1.6 1 0 0 1 1 1 0 GYF domain 2 Methyltransf_23 PF13489.6 CRK30341.1 - 7.1e-07 29.2 0.0 1e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK30341.1 - 1.1e-06 29.3 0.0 3.4e-06 27.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK30341.1 - 8.2e-05 23.2 0.0 0.00042 21.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK30341.1 - 0.029 14.2 0.0 0.68 9.7 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 CRK30341.1 - 0.16 12.7 0.0 0.47 11.1 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Chorismate_bind PF00425.18 CRK30342.1 - 4.3e-65 219.9 0.0 6.5e-65 219.3 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme Acetyltransf_6 PF13480.7 CRK30343.1 - 0.96 9.6 5.3 1.2 9.3 0.3 2.9 2 1 0 3 3 3 0 Acetyltransferase (GNAT) domain FAD_binding_4 PF01565.23 CRK30344.1 - 7.1e-18 64.7 0.1 1.6e-17 63.5 0.1 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 CRK30344.1 - 2.4e-09 37.2 1.5 5.1e-09 36.1 1.5 1.6 1 0 0 1 1 1 1 Berberine and berberine like Lactonase PF10282.9 CRK30345.1 - 1.9e-64 218.1 0.3 2.7e-64 217.6 0.3 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller RNA_polI_A14 PF08203.11 CRK30345.1 - 3.8 8.3 6.2 8.9 7.1 6.2 1.6 1 0 0 1 1 1 0 Yeast RNA polymerase I subunit RPA14 Glyco_hydro_35 PF01301.19 CRK30347.1 - 3.6e-91 306.1 0.6 4.8e-91 305.7 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.9 CRK30347.1 - 1.1e-58 198.0 0.2 1.9e-58 197.3 0.2 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.6 CRK30347.1 - 8e-48 161.8 0.1 1.5e-22 80.3 0.0 2.8 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.6 CRK30347.1 - 8.5e-24 82.9 0.1 1.8e-23 81.9 0.1 1.6 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Aa_trans PF01490.18 CRK30348.1 - 3.1e-42 144.8 31.6 3.5e-42 144.6 31.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CAAD PF14159.6 CRK30348.1 - 0.021 14.7 0.6 0.14 12.0 0.6 2.5 1 0 0 1 1 1 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase DUF5337 PF17272.2 CRK30348.1 - 6 6.8 9.9 16 5.4 5.7 3.0 1 1 1 2 2 2 0 Family of unknown function (DUF5337) Aminotran_3 PF00202.21 CRK30349.1 - 5.2e-93 311.9 0.1 7e-93 311.5 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Fungal_trans PF04082.18 CRK30349.1 - 6.1e-06 25.5 0.1 2.2e-05 23.6 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain MFS_1 PF07690.16 CRK30350.1 - 1.2e-13 50.7 55.1 2.8e-13 49.5 51.1 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily FA_desaturase PF00487.24 CRK30353.1 - 2.5 7.9 8.6 4.6 7.0 8.6 1.4 1 0 0 1 1 1 0 Fatty acid desaturase Acyltransferase PF01553.21 CRK30355.1 - 2.6e-25 88.6 0.0 3.6e-25 88.1 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 CRK30355.1 - 2.8e-13 49.7 0.4 5.2e-13 48.9 0.4 1.4 1 0 0 1 1 1 1 Acyltransferase C-terminus 5_nucleotid_C PF02872.18 CRK30356.1 - 1.3e-48 165.2 0.1 5.9e-35 120.8 0.0 2.5 2 0 0 2 2 2 2 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 CRK30356.1 - 6.1e-12 46.5 0.1 1e-11 45.7 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase YmdB PF13277.6 CRK30356.1 - 0.00017 21.0 0.0 0.00033 20.1 0.0 1.4 1 0 0 1 1 1 1 YmdB-like protein Trp_syntA PF00290.20 CRK30356.1 - 0.021 13.7 0.1 4.8 5.9 0.0 2.4 2 0 0 2 2 2 0 Tryptophan synthase alpha chain DUF3188 PF11384.8 CRK30356.1 - 0.7 9.7 4.8 26 4.6 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3188) DUF4743 PF15916.5 CRK30357.1 - 7.4e-11 42.1 0.0 1.1e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 CRK30357.1 - 9.8e-10 38.6 0.0 2e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain GDA1_CD39 PF01150.17 CRK30358.1 - 3.2e-105 352.2 0.0 4.5e-105 351.7 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family RNase_P_Rpp14 PF01900.19 CRK30359.1 - 4.9e-33 113.4 0.0 6.3e-33 113.1 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family ATP_bind_1 PF03029.17 CRK30360.1 - 2e-94 315.9 0.0 3.7e-68 229.9 0.0 2.1 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein MeaB PF03308.16 CRK30360.1 - 0.005 15.9 0.0 0.01 14.8 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 CRK30360.1 - 0.052 13.6 0.1 0.98 9.5 0.0 2.8 3 1 0 3 3 3 0 50S ribosome-binding GTPase AAA_31 PF13614.6 CRK30360.1 - 0.099 12.6 0.0 2.2 8.2 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CRK30360.1 - 0.12 12.5 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 CRK30360.1 - 0.15 11.3 0.0 0.38 10.0 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.6 CRK30360.1 - 0.18 11.6 0.0 0.36 10.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain cNMP_binding PF00027.29 CRK30361.1 - 2.4e-29 101.2 0.3 6e-16 58.3 0.1 5.5 5 0 0 5 5 5 3 Cyclic nucleotide-binding domain Patatin PF01734.22 CRK30361.1 - 0.0065 16.7 0.0 0.023 14.9 0.0 1.9 1 0 0 1 1 1 1 Patatin-like phospholipase SRCR_2 PF15494.6 CRK30363.1 - 0.017 15.7 4.5 1.9 9.1 1.2 2.1 1 1 1 2 2 2 0 Scavenger receptor cysteine-rich domain PHP PF02811.19 CRK30364.1 - 1.3e-10 41.8 0.0 2.7e-10 40.8 0.0 1.5 1 1 0 1 1 1 1 PHP domain DUF2380 PF09533.10 CRK30364.1 - 0.013 15.1 1.5 0.024 14.3 0.8 1.6 2 0 0 2 2 2 0 Predicted lipoprotein of unknown function (DUF2380) MFS_1 PF07690.16 CRK30366.1 - 5.1e-22 78.3 58.8 1e-19 70.7 38.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Catalase PF00199.19 CRK30367.1 - 3e-186 619.1 0.3 3.6e-186 618.9 0.3 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 CRK30367.1 - 3.3e-09 36.8 0.0 8.4e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive Arf PF00025.21 CRK30368.1 - 2.3e-73 245.4 0.0 2.6e-73 245.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CRK30368.1 - 1.5e-14 54.3 0.0 2e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CRK30368.1 - 2.2e-12 46.8 0.0 2.6e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 CRK30368.1 - 2.7e-11 43.2 0.3 2.5e-07 30.2 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 CRK30368.1 - 4.2e-11 42.7 0.0 5.1e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 CRK30368.1 - 5.9e-08 32.4 0.0 7.5e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CRK30368.1 - 1.3e-06 28.5 0.0 2.1e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CRK30368.1 - 0.0013 18.3 0.0 0.11 12.0 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 CRK30368.1 - 0.0092 15.5 0.9 0.045 13.3 0.8 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_18 PF13238.6 CRK30368.1 - 0.15 12.6 0.1 0.27 11.8 0.0 1.4 1 1 0 1 1 1 0 AAA domain His_Phos_2 PF00328.22 CRK30370.1 - 2.7e-75 254.1 0.0 7.1e-59 200.1 0.0 2.4 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 CRK30370.1 - 8.6e-30 102.7 0.0 1.8e-29 101.7 0.0 1.4 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 CRK30370.1 - 1.4e-07 31.3 0.0 2.6e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 CRK30370.1 - 0.1 12.6 0.0 0.52 10.3 0.0 2.1 2 0 0 2 2 2 0 ATP-grasp domain Git3 PF11710.8 CRK30371.1 - 1.3e-18 67.5 10.0 2.8e-18 66.4 10.0 1.6 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 CRK30371.1 - 1.5e-07 31.0 5.9 2.4e-07 30.4 5.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) GPR_Gpa2_C PF11970.8 CRK30371.1 - 0.00039 20.4 0.1 0.00096 19.2 0.1 1.6 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term Dicty_CAR PF05462.11 CRK30371.1 - 0.011 14.8 5.8 0.02 14.0 5.8 1.3 1 0 0 1 1 1 0 Slime mold cyclic AMP receptor Pec_lyase_C PF00544.19 CRK30373.1 - 3e-43 147.9 9.0 3e-43 147.9 9.0 1.5 2 0 0 2 2 2 1 Pectate lyase Beta_helix PF13229.6 CRK30373.1 - 0.0026 17.6 16.7 0.07 13.0 16.7 2.3 1 1 0 1 1 1 1 Right handed beta helix region Ribosomal_L39 PF00832.20 CRK30374.1 - 6.2e-23 80.2 9.0 7.4e-23 79.9 9.0 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Skp1 PF01466.19 CRK30375.1 - 1.7e-29 101.7 0.4 3.4e-29 100.7 0.4 1.5 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 CRK30375.1 - 1.3e-19 70.1 0.0 3.6e-19 68.7 0.0 1.8 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Glyco_transf_22 PF03901.17 CRK30376.1 - 1.2e-58 199.3 20.0 1.9e-58 198.7 20.0 1.2 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PMT_2 PF13231.6 CRK30376.1 - 0.36 11.0 13.2 0.017 15.3 6.1 2.2 2 0 0 2 2 2 0 Dolichyl-phosphate-mannose-protein mannosyltransferase Ribosomal_L1 PF00687.21 CRK30380.1 - 1.5e-44 152.2 0.1 1.7e-44 152.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Ndr PF03096.14 CRK30380.1 - 0.055 12.2 0.0 0.078 11.7 0.0 1.2 1 0 0 1 1 1 0 Ndr family SNF PF00209.18 CRK30380.1 - 0.085 11.5 0.1 0.12 11.1 0.1 1.1 1 0 0 1 1 1 0 Sodium:neurotransmitter symporter family DUF2428 PF10350.9 CRK30381.1 - 4.8e-60 203.1 0.1 1.2e-59 201.9 0.1 1.7 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 CRK30381.1 - 7.4e-07 28.9 3.1 0.2 12.0 0.0 5.7 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 CRK30381.1 - 0.0088 16.4 9.7 1.6 9.2 2.3 5.4 4 1 0 4 4 4 1 HEAT repeats Uso1_p115_head PF04869.14 CRK30381.1 - 0.061 12.4 1.7 0.11 11.7 0.8 1.8 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, head region HEAT_EZ PF13513.6 CRK30381.1 - 0.068 13.7 6.7 0.13 12.8 0.4 4.1 4 0 0 4 4 4 0 HEAT-like repeat Ribosomal_L1 PF00687.21 CRK30382.1 - 0.00015 21.5 0.1 0.00021 21.1 0.1 1.6 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family Exonuc_VII_L PF02601.15 CRK30382.1 - 0.047 13.3 8.4 0.048 13.2 8.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1796 PF08795.10 CRK30382.1 - 0.085 12.8 2.2 2.4 8.1 2.2 2.1 1 1 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) TPR_MLP1_2 PF07926.12 CRK30382.1 - 0.36 10.9 30.9 1 9.4 30.9 1.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein AAA_13 PF13166.6 CRK30382.1 - 0.43 9.2 12.1 0.56 8.8 12.1 1.1 1 0 0 1 1 1 0 AAA domain DUF3138 PF11336.8 CRK30382.1 - 0.86 8.1 8.1 0.28 9.7 2.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) HAUS-augmin3 PF14932.6 CRK30382.1 - 1.2 8.6 21.2 0.036 13.6 8.9 2.2 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 Neur_chan_memb PF02932.16 CRK30382.1 - 1.8 8.5 4.4 2.1 8.4 4.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CAML PF14963.6 CRK30382.1 - 2.5 8.1 10.4 8.4 6.4 10.7 1.6 2 0 0 2 2 2 0 Calcium signal-modulating cyclophilin ligand Atg14 PF10186.9 CRK30382.1 - 3.7 6.6 20.3 5.3 6.0 20.3 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ALMT PF11744.8 CRK30382.1 - 9.3 5.0 8.0 12 4.6 8.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF2428 PF10350.9 CRK30383.1 - 2e-60 204.4 0.1 4.5e-60 203.2 0.1 1.7 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 CRK30383.1 - 2.6e-05 24.1 8.8 0.2 12.0 0.0 6.1 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 CRK30383.1 - 0.0021 18.4 7.7 0.81 10.1 0.5 5.3 4 1 1 5 5 4 1 HEAT repeats HEAT_EZ PF13513.6 CRK30383.1 - 0.032 14.7 2.5 1 9.9 0.2 4.1 3 0 0 3 3 3 0 HEAT-like repeat Uso1_p115_head PF04869.14 CRK30383.1 - 0.09 11.9 2.2 0.11 11.6 0.8 1.8 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, head region DUF3074 PF11274.8 CRK30384.1 - 1.7e-57 194.3 0.0 1.7e-57 194.3 0.0 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF3074) TSC22 PF01166.18 CRK30384.1 - 0.002 18.4 0.4 5.5 7.4 0.1 3.2 2 0 0 2 2 2 2 TSC-22/dip/bun family DUF1796 PF08795.10 CRK30384.1 - 4 7.4 12.2 2.6 8.0 1.2 4.1 2 2 0 2 2 2 0 Putative papain-like cysteine peptidase (DUF1796) FapA PF03961.13 CRK30384.1 - 4.1 5.9 28.1 3.7 6.1 9.6 2.3 2 0 0 2 2 2 0 Flagellar Assembly Protein A Sod_Fe_N PF00081.22 CRK30384.1 - 4.9 7.7 5.7 57 4.3 0.5 3.1 2 0 0 2 2 2 0 Iron/manganese superoxide dismutases, alpha-hairpin domain VASt PF16016.5 CRK30386.1 - 3.7e-34 118.3 0.3 7.8e-34 117.3 0.3 1.6 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain BAR_3 PF16746.5 CRK30386.1 - 2.5e-12 47.0 0.0 4.4e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 CRK30386.1 - 8.6e-06 26.2 0.0 2e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 PH domain GRAM PF02893.20 CRK30386.1 - 0.021 14.7 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 GRAM domain SIP PF04954.13 CRK30386.1 - 0.087 13.3 1.0 3.1 8.3 0.4 2.8 2 0 0 2 2 2 0 Siderophore-interacting protein DUF1860 PF08949.10 CRK30386.1 - 3.4 7.4 7.2 2.9 7.6 2.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1860) GMC_oxred_N PF00732.19 CRK30389.1 - 5.1e-40 137.7 2.5 6.1e-40 137.4 1.2 1.8 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CRK30389.1 - 9.9e-31 107.2 0.2 8.4e-30 104.2 0.0 2.3 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 CRK30389.1 - 9e-07 28.3 2.5 7.5e-05 22.0 0.8 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 CRK30389.1 - 1.1e-06 28.1 0.4 1.7e-05 24.2 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CRK30389.1 - 1.5e-06 28.0 2.5 0.0027 17.3 0.4 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 CRK30389.1 - 4.5e-05 22.9 0.2 7.4e-05 22.2 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 CRK30389.1 - 4.8e-05 23.5 0.1 0.00015 21.9 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 CRK30389.1 - 0.013 14.2 1.4 0.019 13.7 0.1 1.8 2 1 1 3 3 3 0 HI0933-like protein Thi4 PF01946.17 CRK30389.1 - 0.017 14.4 0.4 0.042 13.1 0.1 1.7 2 0 0 2 2 2 0 Thi4 family UDPG_MGDP_dh_N PF03721.14 CRK30389.1 - 0.04 13.5 0.7 0.082 12.5 0.7 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_oxidored PF12831.7 CRK30389.1 - 0.051 12.9 0.4 0.08 12.3 0.4 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 CRK30389.1 - 0.068 13.0 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 CRK30389.1 - 0.068 12.4 0.0 5.1 6.2 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CRK30389.1 - 0.081 12.0 0.2 0.14 11.1 0.2 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein ApbA PF02558.16 CRK30389.1 - 0.11 12.1 0.2 0.21 11.2 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 CRK30389.1 - 0.12 13.0 0.3 0.3 11.7 0.3 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CRK30389.1 - 0.27 10.3 0.4 0.81 8.7 0.2 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A ELO PF01151.18 CRK30390.1 - 1.2e-80 270.7 9.2 1.4e-80 270.4 9.2 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family DUF423 PF04241.15 CRK30390.1 - 1.3 9.2 7.8 1.6 9.0 0.4 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF423) FYVE PF01363.21 CRK30391.1 - 1e-15 57.6 5.8 1.7e-15 56.9 5.8 1.4 1 0 0 1 1 1 1 FYVE zinc finger zf-AN1 PF01428.16 CRK30391.1 - 5.8 7.2 15.1 0.091 12.9 7.9 1.8 2 0 0 2 2 2 0 AN1-like Zinc finger MoaC PF01967.21 CRK30392.1 - 4.1e-55 185.6 1.2 6.4e-55 185.0 1.2 1.3 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.13 CRK30392.1 - 4.2e-09 36.4 0.0 6.6e-08 32.5 0.0 2.3 2 0 0 2 2 2 1 Molybdenum Cofactor Synthesis C RRM_1 PF00076.22 CRK30393.1 - 6.6e-10 38.7 0.0 0.0032 17.3 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HEAT_2 PF13646.6 CRK30394.1 - 4.2e-08 33.5 9.9 0.1 13.0 0.0 7.1 7 0 0 7 7 7 3 HEAT repeats GATA PF00320.27 CRK30394.1 - 0.00096 18.7 2.6 0.6 9.8 0.2 2.5 2 0 0 2 2 2 2 GATA zinc finger Vac14_Fab1_bd PF12755.7 CRK30394.1 - 0.0016 19.0 0.0 0.35 11.5 0.0 4.0 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 CRK30394.1 - 0.0053 16.9 20.0 2.3 8.7 0.1 9.3 11 0 0 11 11 11 2 HEAT repeat Cnd3 PF12719.7 CRK30394.1 - 0.0056 15.9 0.1 0.25 10.5 0.0 3.3 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain CLASP_N PF12348.8 CRK30394.1 - 0.042 13.4 3.4 7.4 6.1 0.1 4.7 5 0 0 5 5 5 0 CLASP N terminal HEAT_EZ PF13513.6 CRK30394.1 - 0.26 11.8 12.0 24 5.6 0.0 7.4 6 1 1 7 7 7 0 HEAT-like repeat Transcrip_reg PF01709.20 CRK30395.1 - 1.3e-45 155.7 0.0 3.7e-35 121.5 0.0 2.0 1 1 1 2 2 2 2 Transcriptional regulator Ribosomal_S14 PF00253.21 CRK30395.1 - 0.081 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S14p/S29e Pet100 PF09803.9 CRK30396.1 - 1.8e-16 60.4 0.7 5.7e-16 58.8 0.8 1.8 2 0 0 2 2 2 1 Pet100 NUDIX_2 PF13869.6 CRK30400.1 - 6.2e-79 264.0 0.0 8e-79 263.6 0.0 1.1 1 0 0 1 1 1 1 Nucleotide hydrolase HEAT PF02985.22 CRK30401.1 - 2.5e-05 24.1 4.8 7.1 7.2 0.0 7.5 8 0 0 8 8 8 3 HEAT repeat HEAT_2 PF13646.6 CRK30401.1 - 0.001 19.4 10.5 3.1 8.3 0.0 6.2 7 1 0 7 7 7 3 HEAT repeats CLASP_N PF12348.8 CRK30401.1 - 0.33 10.5 1.6 3.8 7.0 0.0 3.5 4 1 1 5 5 5 0 CLASP N terminal Transcrip_reg PF01709.20 CRK30402.1 - 4.1e-60 203.2 0.0 4.7e-60 203.0 0.0 1.0 1 0 0 1 1 1 1 Transcriptional regulator Pet100 PF09803.9 CRK30403.1 - 2.6e-14 53.5 0.8 3.3e-14 53.2 0.8 1.2 1 0 0 1 1 1 1 Pet100 ATPase_gene1 PF09527.10 CRK30403.1 - 0.02 15.1 0.3 0.03 14.5 0.3 1.2 1 0 0 1 1 1 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter Inositol_P PF00459.25 CRK30405.1 - 0.18 11.3 0.2 0.23 11.0 0.2 1.1 1 0 0 1 1 1 0 Inositol monophosphatase family CD20 PF04103.15 CRK30405.1 - 0.71 10.0 4.8 0.3 11.1 2.7 1.4 2 0 0 2 2 2 0 CD20-like family NUDIX_2 PF13869.6 CRK30406.1 - 1.6e-79 265.9 0.0 1.8e-79 265.7 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase SUKH-3 PF14433.6 CRK30406.1 - 0.15 12.5 0.0 12 6.4 0.0 2.9 2 1 0 2 2 2 0 SUKH-3 immunity protein UPF0047 PF01894.17 CRK30407.1 - 5.7e-77 255.3 0.0 5.5e-37 126.4 0.0 2.5 3 0 0 3 3 3 2 Uncharacterised protein family UPF0047 zf-CHCC PF10276.9 CRK30407.1 - 6.3e-16 58.1 0.8 1e-15 57.5 0.8 1.3 1 0 0 1 1 1 1 Zinc-finger domain DUF1326 PF07040.11 CRK30407.1 - 0.049 13.7 0.0 13 5.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1326) Shikimate_dh_N PF08501.11 CRK30407.1 - 0.17 12.1 0.0 40 4.6 0.0 2.6 2 0 0 2 2 2 0 Shikimate dehydrogenase substrate binding domain MPP6 PF10175.9 CRK30408.1 - 5.8e-11 43.0 6.2 3.1e-05 24.5 3.4 2.3 2 1 0 2 2 2 2 M-phase phosphoprotein 6 zf-CCHC PF00098.23 CRK30408.1 - 5.9e-05 23.0 2.3 9.1e-05 22.4 2.3 1.3 1 0 0 1 1 1 1 Zinc knuckle CDC45 PF02724.14 CRK30408.1 - 1.1 7.4 12.2 0.11 10.8 8.1 1.3 2 0 0 2 2 2 0 CDC45-like protein Peptidase_M16 PF00675.20 CRK30409.1 - 2.8e-49 166.9 1.5 4.4e-25 88.4 0.2 2.5 1 1 1 2 2 2 2 Insulinase (Peptidase family M16) Peptidase_M16_M PF16187.5 CRK30409.1 - 9.9e-48 162.8 0.5 4e-47 160.9 0.1 1.9 1 1 1 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 CRK30409.1 - 2.3e-23 83.2 0.0 1.5e-17 64.2 0.0 2.4 2 0 0 2 2 2 2 Peptidase M16 inactive domain PA14 PF07691.12 CRK30409.1 - 0.09 12.6 0.0 8.2 6.2 0.0 2.4 2 0 0 2 2 2 0 PA14 domain UCH PF00443.29 CRK30410.1 - 2.5e-34 118.9 0.4 2.2e-20 73.3 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 CRK30410.1 - 1.5e-12 48.0 0.0 1.8e-11 44.5 0.0 2.5 2 0 0 2 2 2 1 DUSP domain UCH_1 PF13423.6 CRK30410.1 - 3.3e-07 30.2 0.9 0.013 15.1 0.0 2.6 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Pro_Al_protease PF02983.14 CRK30410.1 - 0.069 13.2 0.5 0.3 11.2 0.0 2.4 2 0 0 2 2 2 0 Alpha-lytic protease prodomain Zn_ribbon_SprT PF17283.2 CRK30410.1 - 0.24 11.3 0.9 0.43 10.5 0.9 1.4 1 0 0 1 1 1 0 SprT-like zinc ribbon domain PDEase_I PF00233.19 CRK30412.1 - 2e-59 201.2 0.0 3e-59 200.6 0.0 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase DUF2505 PF10698.9 CRK30412.1 - 0.13 12.3 0.1 0.27 11.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2505) DUF2505 PF10698.9 CRK30413.1 - 0.03 14.4 0.1 0.045 13.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2505) Peptidase_S10 PF00450.22 CRK30414.1 - 1.5e-128 429.8 3.1 1.9e-128 429.4 3.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.11 CRK30414.1 - 2e-16 60.7 4.3 3.9e-15 56.5 4.3 2.5 1 1 0 1 1 1 1 Carboxypeptidase Y pro-peptide SBDS_C PF09377.10 CRK30415.1 - 2e-44 150.3 0.0 3.3e-44 149.6 0.0 1.4 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 CRK30415.1 - 4.1e-35 119.7 0.3 7.5e-35 118.9 0.3 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Ribosomal_S13 PF00416.22 CRK30416.1 - 1.4e-54 183.9 3.3 1.7e-54 183.7 3.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 CRK30416.1 - 0.024 13.4 0.0 0.033 13.0 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) PX PF00787.24 CRK30418.1 - 7.2e-18 64.6 0.0 1.9e-17 63.3 0.0 1.8 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 CRK30418.1 - 1.2e-08 34.8 15.5 2.9e-06 27.0 0.6 2.9 3 0 0 3 3 3 2 Vps5 C terminal like Fructosamin_kin PF03881.14 CRK30420.1 - 9.6e-37 126.7 0.0 1.2e-36 126.5 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 CRK30420.1 - 2.8e-05 24.2 0.0 5.6e-05 23.2 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family ANAPC4_WD40 PF12894.7 CRK30423.1 - 1.8e-12 47.4 0.0 0.062 13.6 0.0 4.9 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain PGAP1 PF07819.13 CRK30423.1 - 9e-06 25.6 0.0 1.8e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 CRK30423.1 - 0.00033 21.3 1.0 0.0021 18.7 0.0 2.8 3 0 0 3 3 3 1 Alpha/beta hydrolase family WD40 PF00400.32 CRK30423.1 - 0.00041 21.1 0.0 22 6.1 0.0 5.5 5 0 0 5 5 5 1 WD domain, G-beta repeat NACHT PF05729.12 CRK30423.1 - 0.0017 18.3 0.0 0.0036 17.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain DUF676 PF05057.14 CRK30423.1 - 0.02 14.4 0.0 0.047 13.2 0.0 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) AAA_16 PF13191.6 CRK30423.1 - 0.072 13.5 0.0 0.41 11.0 0.0 2.3 1 1 1 2 2 2 0 AAA ATPase domain COesterase PF00135.28 CRK30424.1 - 6.5e-60 203.5 0.0 1.3e-59 202.5 0.0 1.5 2 0 0 2 2 2 1 Carboxylesterase family Peptidase_S9 PF00326.21 CRK30424.1 - 0.0014 18.1 0.0 0.0024 17.4 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 CRK30424.1 - 0.002 18.0 1.9 0.002 18.0 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold mRNA_cap_enzyme PF01331.19 CRK30427.1 - 2.4e-57 193.9 0.3 3.1e-57 193.6 0.3 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 CRK30427.1 - 3.2e-31 108.2 0.0 6e-31 107.3 0.0 1.5 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 CRK30427.1 - 1.6e-09 37.7 0.1 6.5e-05 22.7 0.0 2.3 1 1 1 2 2 2 2 ATP dependent DNA ligase domain Ribosomal_L41 PF05162.13 CRK30428.1 - 1.6e-11 44.0 29.0 1.8e-11 43.9 29.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L41 Pkinase PF00069.25 CRK30431.1 - 2.5e-53 181.1 0.0 3.7e-53 180.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK30431.1 - 1.1e-20 74.0 0.0 1.8e-20 73.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 CRK30431.1 - 1.3e-05 25.5 1.2 2.2e-05 24.7 0.1 2.0 2 0 0 2 2 2 1 FHA domain Pkinase_fungal PF17667.1 CRK30431.1 - 2.7e-05 23.2 0.0 5.3e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CRK30431.1 - 0.0012 18.2 0.0 0.0029 17.0 0.0 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CRK30431.1 - 0.13 11.5 0.0 0.32 10.3 0.0 1.6 1 0 0 1 1 1 0 Kinase-like DUF3543 PF12063.8 CRK30433.1 - 1.8e-90 302.7 0.6 2.8e-90 302.1 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.25 CRK30433.1 - 1.4e-59 201.6 0.0 2.6e-59 200.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK30433.1 - 1.7e-40 139.0 0.0 3.3e-40 138.0 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Aminotran_3 PF00202.21 CRK30437.1 - 1.1e-118 396.4 0.0 1.3e-118 396.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 CRK30437.1 - 6.8e-05 22.3 0.0 0.00014 21.2 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Glyco_transf_22 PF03901.17 CRK30439.1 - 6.1e-77 259.6 14.1 7.4e-77 259.3 14.1 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family RhoGAP PF00620.27 CRK30441.1 - 5.6e-39 133.4 0.0 8.8e-39 132.8 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Peptidase_M16_M PF16187.5 CRK30443.1 - 1.7e-98 329.4 0.2 3.6e-98 328.3 0.2 1.6 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 UCH PF00443.29 CRK30443.1 - 1.2e-60 205.2 0.0 3e-60 203.9 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_M16_C PF05193.21 CRK30443.1 - 1.4e-31 109.9 0.0 3.2e-15 56.6 0.0 2.6 2 0 0 2 2 2 2 Peptidase M16 inactive domain DUSP PF06337.12 CRK30443.1 - 5.1e-12 46.2 0.0 3.1e-11 43.7 0.0 2.4 2 0 0 2 2 2 1 DUSP domain UCH_1 PF13423.6 CRK30443.1 - 2.2e-10 40.6 0.0 0.00028 20.6 0.0 3.3 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Pro_Al_protease PF02983.14 CRK30443.1 - 0.15 12.1 0.7 0.36 10.9 0.0 2.0 2 0 0 2 2 2 0 Alpha-lytic protease prodomain Zn_ribbon_SprT PF17283.2 CRK30443.1 - 5.6 6.9 5.0 0.77 9.7 0.9 1.7 2 0 0 2 2 2 0 SprT-like zinc ribbon domain PDEase_I PF00233.19 CRK30445.1 - 1.9e-66 224.2 0.0 2.7e-66 223.7 0.0 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Peptidase_S10 PF00450.22 CRK30445.1 - 1.1e-40 140.3 0.0 1.6e-40 139.8 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase SBDS_C PF09377.10 CRK30446.1 - 3e-44 149.8 0.0 5e-44 149.0 0.0 1.4 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 CRK30446.1 - 4.1e-35 119.7 0.3 7.5e-35 118.9 0.3 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Ribosomal_S13 PF00416.22 CRK30447.1 - 1.2e-54 184.1 3.3 1.4e-54 183.9 3.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 CRK30447.1 - 0.019 13.7 0.0 0.026 13.3 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) PX PF00787.24 CRK30448.1 - 6.2e-18 64.8 0.0 1.5e-17 63.6 0.0 1.7 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 CRK30448.1 - 2.1e-09 37.3 9.4 1.6e-05 24.6 0.3 2.2 2 0 0 2 2 2 2 Vps5 C terminal like MFS_1 PF07690.16 CRK30449.1 - 4.2e-25 88.4 44.4 5.5e-23 81.5 29.8 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily Folate_carrier PF01770.18 CRK30449.1 - 0.0001 21.2 0.5 0.00038 19.3 0.3 1.9 1 1 1 2 2 2 1 Reduced folate carrier HET PF06985.11 CRK30450.1 - 1.4e-32 113.1 0.2 2.3e-32 112.4 0.2 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) COesterase PF00135.28 CRK30451.1 - 5.6e-59 200.4 0.0 1.1e-58 199.4 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CRK30451.1 - 0.0013 18.7 1.0 0.0017 18.2 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CRK30451.1 - 0.0041 16.6 0.0 0.0075 15.8 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family mRNA_cap_enzyme PF01331.19 CRK30452.1 - 2.4e-57 193.9 0.3 3.1e-57 193.6 0.3 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 CRK30452.1 - 7.8e-31 106.9 0.0 1.5e-30 106.0 0.0 1.5 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 CRK30452.1 - 1.6e-09 37.7 0.1 6.5e-05 22.7 0.0 2.3 1 1 1 2 2 2 2 ATP dependent DNA ligase domain Pkinase PF00069.25 CRK30453.1 - 9.2e-55 185.8 0.0 1.3e-54 185.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK30453.1 - 2.6e-21 76.1 0.0 4e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CRK30453.1 - 1.3e-05 24.2 0.1 4.3e-05 22.5 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase FHA PF00498.26 CRK30453.1 - 1.5e-05 25.2 3.0 2e-05 24.9 0.0 2.8 4 0 0 4 4 4 1 FHA domain Kdo PF06293.14 CRK30453.1 - 0.0012 18.2 0.0 0.0031 16.9 0.0 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CRK30453.1 - 0.026 13.8 0.0 0.06 12.7 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Zeta_toxin PF06414.12 CRK30454.1 - 5.7e-44 149.8 0.0 8.2e-44 149.3 0.0 1.1 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.6 CRK30454.1 - 7.5e-07 29.4 0.0 1.7e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CRK30454.1 - 0.00092 19.6 2.6 0.0011 19.4 0.2 2.0 1 1 1 2 2 2 1 AAA ATPase domain TsaE PF02367.17 CRK30454.1 - 0.0091 16.0 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE TrwB_AAD_bind PF10412.9 CRK30454.1 - 0.017 14.0 0.0 0.16 10.8 0.0 2.1 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Sigma54_activat PF00158.26 CRK30454.1 - 0.023 14.4 0.0 0.047 13.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain SRP54 PF00448.22 CRK30454.1 - 0.05 13.2 0.0 0.096 12.3 0.0 1.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_22 PF13401.6 CRK30454.1 - 0.062 13.6 0.0 0.13 12.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain DUF3543 PF12063.8 CRK30455.1 - 1.3e-90 303.2 0.6 3e-90 302.0 0.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.25 CRK30455.1 - 2.5e-59 200.8 0.0 4.6e-59 199.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK30455.1 - 2.6e-40 138.4 0.0 4.7e-40 137.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Zn_clus PF00172.18 CRK30455.1 - 7.5 6.8 6.5 74 3.6 6.3 2.2 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_3 PF00202.21 CRK30456.1 - 1.2e-118 396.3 0.0 1.4e-118 396.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 CRK30456.1 - 6.8e-05 22.3 0.0 0.00014 21.2 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Glyco_transf_22 PF03901.17 CRK30457.1 - 3e-59 201.3 12.9 4.4e-53 181.0 6.6 2.0 1 1 1 2 2 2 2 Alg9-like mannosyltransferase family Use1 PF09753.9 CRK30458.1 - 2.3e-08 34.1 0.7 2.3e-08 34.1 0.7 2.3 2 1 0 2 2 2 1 Membrane fusion protein Use1 Phage_Gp23 PF10669.9 CRK30458.1 - 0.066 13.5 2.3 12 6.2 0.0 2.8 2 1 1 3 3 3 0 Protein gp23 (Bacteriophage A118) BRCT_2 PF16589.5 CRK30459.1 - 2.2e-05 24.8 0.0 5.6e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 CRK30459.1 - 0.0029 17.9 0.0 0.0071 16.7 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 CRK30459.1 - 0.009 15.9 0.1 0.024 14.6 0.1 1.7 1 0 0 1 1 1 1 twin BRCT domain Adaptin_binding PF10199.9 CRK30459.1 - 0.18 12.4 0.1 0.18 12.4 0.1 2.9 2 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 IGPS PF00218.21 CRK30460.1 - 9e-96 319.9 0.0 1.5e-95 319.2 0.0 1.3 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase PRAI PF00697.22 CRK30460.1 - 7.3e-48 162.9 0.0 4.3e-45 153.9 0.0 2.3 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.28 CRK30460.1 - 9.3e-48 162.5 0.0 7.2e-47 159.6 0.0 2.1 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 CRK30460.1 - 7.6e-05 22.6 0.2 0.00034 20.4 0.2 2.0 1 1 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.19 CRK30460.1 - 0.037 13.8 0.7 0.32 10.8 0.3 2.4 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain NanE PF04131.14 CRK30460.1 - 0.14 11.3 0.2 1.3 8.2 0.1 2.5 3 0 0 3 3 3 0 Putative N-acetylmannosamine-6-phosphate epimerase Nup188 PF10487.9 CRK30461.1 - 6e-09 34.4 0.0 6.7e-09 34.3 0.0 1.1 1 0 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 WASH-7_mid PF14744.6 CRK30461.1 - 0.069 12.2 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 WASH complex subunit 7 Fasciclin PF02469.22 CRK30461.1 - 0.19 11.9 0.4 0.36 11.1 0.4 1.4 1 0 0 1 1 1 0 Fasciclin domain Use1 PF09753.9 CRK30462.1 - 5e-10 39.5 2.4 5e-09 36.2 0.0 2.3 2 1 0 2 2 2 1 Membrane fusion protein Use1 Phage_Gp23 PF10669.9 CRK30462.1 - 0.077 13.3 2.0 12 6.2 0.0 2.8 2 1 1 3 3 3 0 Protein gp23 (Bacteriophage A118) BRCT_2 PF16589.5 CRK30463.1 - 2.3e-05 24.7 0.0 6e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 CRK30463.1 - 0.0042 17.4 0.0 0.01 16.2 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 CRK30463.1 - 0.018 15.0 0.1 0.046 13.7 0.1 1.7 1 0 0 1 1 1 0 twin BRCT domain Nup188_C PF18378.1 CRK30465.1 - 6.1e-154 512.3 0.1 1e-153 511.6 0.1 1.4 1 0 0 1 1 1 1 Nuclear pore protein NUP188 C-terminal domain Nup188 PF10487.9 CRK30465.1 - 1.8e-49 168.6 0.7 2.9e-33 114.9 0.2 2.9 2 1 0 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 zf-Tim10_DDP PF02953.15 CRK30466.1 - 9.6e-18 63.6 5.3 1.4e-17 63.1 5.3 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger c-SKI_SMAD_bind PF08782.10 CRK30466.1 - 0.042 14.1 0.7 0.062 13.5 0.7 1.3 1 0 0 1 1 1 0 c-SKI Smad4 binding domain DUF86 PF01934.17 CRK30466.1 - 0.08 12.8 0.1 0.086 12.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF86 G-alpha PF00503.20 CRK30467.1 - 1.1e-124 416.2 2.5 1.3e-124 415.9 2.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CRK30467.1 - 3.7e-15 55.8 2.0 2.8e-10 39.9 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.20 CRK30467.1 - 8.5e-05 22.3 0.0 0.00036 20.3 0.0 1.9 2 0 0 2 2 2 1 CHC2 zinc finger Gtr1_RagA PF04670.12 CRK30467.1 - 0.0019 17.6 2.9 0.11 11.9 0.0 2.7 2 1 1 3 3 3 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.6 CRK30467.1 - 0.014 15.1 0.0 0.033 13.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 CRK30467.1 - 0.024 14.9 0.2 2.4 8.4 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MCM PF00493.23 CRK30467.1 - 0.058 12.5 0.1 0.11 11.6 0.1 1.5 1 1 0 1 1 1 0 MCM P-loop domain GTP_EFTU PF00009.27 CRK30467.1 - 0.12 11.9 0.0 1.6 8.2 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.18 CRK30467.1 - 0.12 11.7 0.0 0.28 10.5 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 CRK30467.1 - 0.13 12.3 0.1 8.8 6.5 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF3716 PF12511.8 CRK30468.1 - 8.8e-16 57.7 10.4 1.4e-15 57.1 10.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) D123 PF07065.14 CRK30469.1 - 2.1e-112 375.3 0.0 2.4e-112 375.1 0.0 1.0 1 0 0 1 1 1 1 D123 cwf21 PF08312.12 CRK30470.1 - 1.2e-17 63.8 15.8 3.8e-17 62.2 15.8 1.9 1 0 0 1 1 1 1 cwf21 domain GvpG PF05120.12 CRK30470.1 - 0.017 15.2 10.6 0.037 14.1 2.4 2.4 2 1 0 2 2 2 0 Gas vesicle protein G DUF4407 PF14362.6 CRK30470.1 - 0.88 8.9 5.1 0.94 8.8 5.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NDUFA12 PF05071.16 CRK30471.1 - 1e-10 42.3 2.8 2.9e-10 40.8 0.2 2.2 2 0 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 CH PF00307.31 CRK30472.1 - 7e-14 51.9 0.0 1.2e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain Hce2 PF14856.6 CRK30472.1 - 4.9e-13 49.2 0.0 1.2e-12 48.0 0.0 1.7 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor Helo_like_N PF17111.5 CRK30472.1 - 0.013 14.9 0.1 0.013 14.9 0.1 2.7 2 1 0 2 2 2 0 Fungal N-terminal domain of STAND proteins SesA PF17107.5 CRK30472.1 - 0.022 15.0 0.5 0.058 13.6 0.5 1.8 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases CAMSAP_CH PF11971.8 CRK30472.1 - 0.15 11.9 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 CAMSAP CH domain DUF4449 PF14613.6 CRK30473.1 - 2.3e-70 235.9 5.2 2.3e-70 235.9 5.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) APH PF01636.23 CRK30473.1 - 8.7e-15 55.3 0.0 4.4e-13 49.7 0.0 2.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.11 CRK30473.1 - 0.016 14.1 0.1 0.041 12.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) JHBP PF06585.11 CRK30473.1 - 0.027 13.7 1.8 0.088 12.0 1.8 1.8 1 0 0 1 1 1 0 Haemolymph juvenile hormone binding protein (JHBP) EcKinase PF02958.20 CRK30473.1 - 0.17 11.2 0.0 0.17 11.2 0.0 2.6 3 0 0 3 3 3 0 Ecdysteroid kinase TPR_6 PF13174.6 CRK30473.1 - 1.5 9.6 3.4 1.6e+02 3.2 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat GlutR_dimer PF00745.20 CRK30473.1 - 2.6 8.6 4.9 37 4.9 0.7 3.6 4 0 0 4 4 4 0 Glutamyl-tRNAGlu reductase, dimerisation domain Ndc1_Nup PF09531.10 CRK30473.1 - 6 5.4 9.7 0.074 11.7 1.0 1.9 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup SOG2 PF10428.9 CRK30474.1 - 3.3 6.8 7.1 3.4 6.8 7.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Podoplanin PF05808.11 CRK30475.1 - 0.002 18.2 0.0 0.0039 17.3 0.0 1.5 1 0 0 1 1 1 1 Podoplanin DUF1010 PF06231.11 CRK30475.1 - 0.15 12.6 0.6 0.37 11.3 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1010) Gram_pos_anchor PF00746.21 CRK30475.1 - 0.23 11.4 2.0 0.51 10.3 2.0 1.6 1 0 0 1 1 1 0 LPXTG cell wall anchor motif DNA_ligase_A_M PF01068.21 CRK30476.1 - 1.5e-44 152.1 0.0 3.9e-44 150.8 0.0 1.7 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 CRK30476.1 - 1.3e-41 142.8 0.0 2.8e-41 141.7 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus RNA_ligase PF09414.10 CRK30476.1 - 1.6e-18 67.6 0.0 3.2e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 RNA ligase BRCT_2 PF16589.5 CRK30476.1 - 2.8e-13 50.1 0.0 2.2e-08 34.4 0.0 2.4 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain DNA_ligase_A_C PF04679.15 CRK30476.1 - 5.5e-13 49.4 0.3 9.5e-12 45.4 0.0 2.6 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region BRCT PF00533.26 CRK30476.1 - 1.3e-06 28.7 0.0 7.7e-06 26.2 0.0 2.2 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 CRK30476.1 - 0.00011 22.4 0.0 0.51 10.7 0.0 2.5 2 0 0 2 2 2 2 DNA ligase 3 BRCT domain DNA_ligase_IV PF11411.8 CRK30476.1 - 0.0019 18.3 0.0 0.0042 17.2 0.0 1.6 1 0 0 1 1 1 1 DNA ligase IV mRNA_cap_enzyme PF01331.19 CRK30476.1 - 0.0097 15.7 0.1 0.35 10.7 0.1 2.6 1 1 0 1 1 1 1 mRNA capping enzyme, catalytic domain UPRTase PF14681.6 CRK30477.1 - 2.7e-73 245.8 0.0 3.7e-73 245.4 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 CRK30477.1 - 0.0046 16.5 0.3 0.018 14.6 0.3 1.8 1 1 0 1 1 1 1 Phosphoribosyl transferase domain NAD_binding_10 PF13460.6 CRK30477.1 - 0.017 15.0 0.0 0.024 14.5 0.0 1.2 1 0 0 1 1 1 0 NAD(P)H-binding TMP-TENI PF02581.17 CRK30477.1 - 0.066 12.5 1.0 0.7 9.2 0.7 2.1 2 0 0 2 2 2 0 Thiamine monophosphate synthase CRCB PF02537.15 CRK30478.1 - 8.9e-40 134.9 10.5 3.8e-24 84.8 4.6 2.3 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) Herpes_LMP1 PF05297.11 CRK30478.1 - 0.033 13.4 4.9 0.051 12.8 4.9 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF4360 PF14273.6 CRK30479.1 - 2.9e-57 193.4 2.3 3.3e-57 193.2 2.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) OmdA PF13376.6 CRK30480.1 - 3.1e-20 71.9 0.8 3.1e-20 71.9 0.8 2.1 2 0 0 2 2 2 1 Bacteriocin-protection, YdeI or OmpD-Associated GSH_synth_ATP PF03917.17 CRK30481.1 - 2.7e-129 431.2 0.0 3.2e-129 431.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 CRK30481.1 - 2.8e-33 114.4 0.0 5.4e-33 113.5 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic glutathione synthase SSB PF00436.25 CRK30482.1 - 5.9e-20 71.3 0.0 7.1e-20 71.0 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family DUF4741 PF15897.5 CRK30482.1 - 0.081 12.7 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4741) STE3 PF02076.15 CRK30483.1 - 4e-68 229.8 15.6 4.9e-68 229.5 15.6 1.1 1 0 0 1 1 1 1 Pheromone A receptor 7TM_GPCR_Srw PF10324.9 CRK30483.1 - 0.015 14.6 0.0 0.026 13.8 0.0 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw Erf4 PF10256.9 CRK30484.1 - 1.7e-37 128.1 0.0 2.6e-37 127.5 0.0 1.3 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Tmemb_9 PF05434.11 CRK30484.1 - 0.0028 17.6 0.0 0.0054 16.6 0.0 1.4 1 0 0 1 1 1 1 TMEM9 PBP1_TM PF14812.6 CRK30484.1 - 0.47 10.8 0.0 0.47 10.8 0.0 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4407 PF14362.6 CRK30485.1 - 0.014 14.8 3.2 0.023 14.1 3.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HCV_NS1 PF01560.17 CRK30485.1 - 0.17 10.6 0.0 0.25 10.0 0.0 1.1 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein E2/NS1 SBF_like PF13593.6 CRK30486.1 - 4.4e-83 279.2 17.0 5e-83 279.0 17.0 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 CRK30486.1 - 2e-05 24.4 9.7 2e-05 24.4 9.7 1.9 2 1 0 2 2 2 1 Sodium Bile acid symporter family Mem_trans PF03547.18 CRK30486.1 - 0.15 10.4 0.0 0.15 10.4 0.0 2.7 3 1 0 3 3 3 0 Membrane transport protein DUF2236 PF09995.9 CRK30486.1 - 0.3 11.2 5.7 3.6 7.7 1.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2236) Frag1 PF10277.9 CRK30486.1 - 0.84 9.1 9.1 0.28 10.7 0.1 2.5 2 0 0 2 2 2 0 Frag1/DRAM/Sfk1 family DUF373 PF04123.13 CRK30486.1 - 1.8 7.9 9.8 0.29 10.5 4.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF373) Glyco_hydro_1 PF00232.18 CRK30487.1 - 1.8e-31 109.1 0.2 2.1e-31 108.9 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Aldo_ket_red PF00248.21 CRK30488.1 - 1.9e-37 129.1 0.0 2.8e-35 121.9 0.0 2.4 1 1 0 1 1 1 1 Aldo/keto reductase family GFA PF04828.14 CRK30488.1 - 0.015 15.7 0.0 0.036 14.4 0.0 1.6 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme zinc_ribbon_2 PF13240.6 CRK30488.1 - 0.093 12.5 0.3 0.22 11.3 0.3 1.7 1 0 0 1 1 1 0 zinc-ribbon domain SSrecog PF03531.14 CRK30489.1 - 1.7e-30 104.7 0.2 9.7e-30 102.3 0.0 2.4 2 0 0 2 2 2 1 Structure-specific recognition protein (SSRP1) POB3_N PF17292.2 CRK30489.1 - 4.2e-29 100.8 0.1 1.3e-28 99.2 0.0 1.9 2 0 0 2 2 2 1 POB3-like N-terminal PH domain AMP-binding PF00501.28 CRK30490.1 - 4.4e-71 239.7 0.0 5.3e-71 239.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CRK30490.1 - 5.1e-20 72.2 0.4 1.1e-19 71.1 0.4 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PBD PF00786.28 CRK30493.1 - 0.083 13.3 0.0 0.25 11.7 0.0 1.9 1 0 0 1 1 1 0 P21-Rho-binding domain Cellsynth_D PF03500.13 CRK30497.1 - 0.18 11.7 0.0 7.4 6.4 0.0 2.6 3 0 0 3 3 3 0 Cellulose synthase subunit D Mg_trans_NIPA PF05653.14 CRK30498.1 - 7.6e-61 205.8 6.2 1.8e-58 198.0 4.5 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA SLC35F PF06027.12 CRK30498.1 - 0.0092 15.5 2.2 2.8 7.4 0.8 2.4 2 0 0 2 2 2 2 Solute carrier family 35 TssN PF17555.2 CRK30498.1 - 1.6 8.0 6.2 2.7 7.3 6.2 1.3 1 0 0 1 1 1 0 Type VI secretion system, TssN DUF1461 PF07314.11 CRK30498.1 - 3.9 7.3 4.9 1.2 9.0 1.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1461) RRM_1 PF00076.22 CRK30499.1 - 4.9e-23 80.7 0.1 8.7e-15 54.3 0.0 4.2 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 CRK30499.1 - 0.016 15.0 0.4 0.41 10.4 0.2 2.7 1 1 1 2 2 2 0 Rrp7 RRM-like N-terminal domain FUSC PF04632.12 CRK30499.1 - 0.75 8.3 1.6 1.5 7.3 1.6 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family PBD PF00786.28 CRK30500.1 - 0.08 13.3 0.0 0.25 11.7 0.0 1.9 1 0 0 1 1 1 0 P21-Rho-binding domain AMP-binding PF00501.28 CRK30501.1 - 2e-70 237.6 0.0 2.8e-70 237.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CRK30501.1 - 2.3e-10 41.3 0.1 8.1e-10 39.5 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain HLH PF00010.26 CRK30501.1 - 4.7e-09 36.1 0.2 9.5e-09 35.1 0.2 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SOG2 PF10428.9 CRK30501.1 - 6.1 5.9 17.1 14 4.8 17.1 1.6 1 0 0 1 1 1 0 RAM signalling pathway protein DUF647 PF04884.14 CRK30502.1 - 0.095 12.3 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 Vitamin B6 photo-protection and homoeostasis SSrecog PF03531.14 CRK30503.1 - 2.2e-30 104.3 0.2 1.2e-29 102.0 0.0 2.4 2 0 0 2 2 2 1 Structure-specific recognition protein (SSRP1) POB3_N PF17292.2 CRK30503.1 - 2.6e-30 104.7 0.2 1.7e-28 98.9 0.0 2.8 3 0 0 3 3 3 1 POB3-like N-terminal PH domain Rtt106 PF08512.12 CRK30503.1 - 3.1e-22 78.8 0.1 2.2e-21 76.1 0.0 2.4 3 0 0 3 3 3 1 Histone chaperone Rttp106-like Rtt106 PF08512.12 CRK30504.1 - 6.6e-13 48.9 0.0 8.3e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 Histone chaperone Rttp106-like SDA1 PF05285.12 CRK30504.1 - 1.4 8.3 19.0 1.6 8.1 19.0 1.0 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 CRK30504.1 - 9.3 4.4 14.0 10 4.2 14.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Aldo_ket_red PF00248.21 CRK30505.1 - 5.7e-40 137.3 0.0 8.6e-17 61.3 0.0 2.9 2 1 1 3 3 3 3 Aldo/keto reductase family DUF4203 PF13886.6 CRK30506.1 - 9.5e-56 188.7 26.8 1.3e-55 188.2 26.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Glyco_hydro_1 PF00232.18 CRK30507.1 - 4.3e-149 496.8 0.0 5.1e-149 496.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 SBF_like PF13593.6 CRK30508.1 - 1.3e-84 284.2 15.0 1.5e-84 284.0 15.0 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 CRK30508.1 - 3.8e-07 30.0 7.1 3.8e-07 30.0 7.1 2.2 3 1 0 3 3 3 1 Sodium Bile acid symporter family DUF4203 PF13886.6 CRK30509.1 - 2.1e-54 184.3 26.3 2.9e-54 183.8 26.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) HCV_NS1 PF01560.17 CRK30511.1 - 0.13 10.9 0.0 0.2 10.3 0.0 1.1 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein E2/NS1 TMEM251 PF15190.6 CRK30511.1 - 0.14 12.1 0.1 0.27 11.2 0.1 1.4 1 0 0 1 1 1 0 Transmembrane protein 251 DUF3391 PF11871.8 CRK30511.1 - 8.4 6.9 7.4 1.1e+02 3.3 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) Erf4 PF10256.9 CRK30513.1 - 1.1e-37 128.6 0.0 1.7e-37 128.1 0.0 1.3 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family STE3 PF02076.15 CRK30515.1 - 1.1e-67 228.4 15.3 1.3e-67 228.1 15.3 1.1 1 0 0 1 1 1 1 Pheromone A receptor SSB PF00436.25 CRK30517.1 - 4.3e-20 71.7 0.0 5.1e-20 71.5 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family Kinocilin PF15033.6 CRK30517.1 - 0.05 13.3 0.0 0.083 12.5 0.0 1.3 1 0 0 1 1 1 0 Kinocilin protein DUF4741 PF15897.5 CRK30517.1 - 0.068 13.0 0.0 0.093 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4741) SNF2_N PF00176.23 CRK30520.1 - 5.2e-84 281.9 0.0 8.8e-42 143.1 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 CRK30520.1 - 8.6e-21 74.4 0.0 2.1e-20 73.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CRK30520.1 - 2.7e-17 63.3 0.0 5.1e-08 33.1 0.0 2.9 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 CRK30520.1 - 2.2e-11 43.9 2.4 5.6e-05 22.9 0.1 4.1 3 2 0 3 3 3 2 SWI2/SNF2 ATPase DEAD PF00270.29 CRK30520.1 - 5e-10 39.4 0.0 0.00088 19.1 0.0 3.0 2 0 0 2 2 2 2 DEAD/DEAH box helicase DUF1192 PF06698.11 CRK30520.1 - 0.00055 19.9 2.5 0.86 9.7 0.1 3.2 3 0 0 3 3 2 2 Protein of unknown function (DUF1192) DUF2497 PF10691.9 CRK30520.1 - 0.013 15.9 0.9 8.9 6.8 0.1 3.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2497) Peptidase_M32 PF02074.15 CRK30520.1 - 0.028 13.2 3.2 1.8 7.3 0.1 2.4 2 0 0 2 2 2 0 Carboxypeptidase Taq (M32) metallopeptidase GDH_N PF12466.8 CRK30520.1 - 0.034 14.3 0.4 6.8 7.0 0.0 3.0 2 0 0 2 2 2 0 Glutamate dehydrogenase N terminal ERCC3_RAD25_C PF16203.5 CRK30520.1 - 0.036 13.3 0.1 0.069 12.3 0.1 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase DUF2075 PF09848.9 CRK30520.1 - 0.036 13.3 0.0 7.4 5.7 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) BLOC1S3 PF15753.5 CRK30520.1 - 3.5 7.7 11.4 8.1 6.5 2.9 3.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 kleA_kleC PF17383.2 CRK30520.1 - 3.9 7.9 10.1 30 5.1 0.1 4.2 2 1 1 3 3 3 0 Uncharacterized KorC regulated protein A GSH_synth_ATP PF03917.17 CRK30522.1 - 2.3e-59 201.1 0.0 2.6e-59 200.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain Aminotran_1_2 PF00155.21 CRK30527.1 - 8.6e-32 110.7 1.2 1e-31 110.5 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class I and II Helicase_C PF00271.31 CRK30527.1 - 7.6e-21 74.5 0.2 2.5e-20 72.8 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Cys_Met_Meta_PP PF01053.20 CRK30527.1 - 0.0066 15.0 0.2 0.33 9.5 0.1 2.9 3 0 0 3 3 3 1 Cys/Met metabolism PLP-dependent enzyme DUF3405 PF11885.8 CRK30527.1 - 0.66 8.5 3.9 0.16 10.6 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3405) Sulfotransfer_3 PF13469.6 CRK30527.1 - 2 8.8 4.2 1.8 8.9 2.1 2.0 2 0 0 2 2 2 0 Sulfotransferase family TMP-TENI PF02581.17 CRK30529.1 - 2.3e-101 336.6 16.5 8.2e-56 188.2 3.8 2.4 1 1 1 2 2 2 2 Thiamine monophosphate synthase HK PF02110.15 CRK30529.1 - 6.1e-71 238.7 5.5 1.1e-70 237.8 5.5 1.5 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family DUF3721 PF12518.8 CRK30529.1 - 0.053 13.4 0.1 21 5.0 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function Isochorismatase PF00857.20 CRK30533.1 - 2.1e-31 109.5 0.5 2.7e-31 109.1 0.5 1.1 1 0 0 1 1 1 1 Isochorismatase family SIS_2 PF13580.6 CRK30533.1 - 0.068 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 SIS domain RhlB PF12300.8 CRK30534.1 - 0.081 13.1 12.5 0.1 12.7 12.5 1.2 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB U3snoRNP10 PF12397.8 CRK30536.1 - 4.7e-14 52.7 0.8 7.6e-13 48.8 0.0 3.2 3 1 1 4 4 4 1 U3 small nucleolar RNA-associated protein 10 HEAT_EZ PF13513.6 CRK30536.1 - 0.05 14.1 1.6 0.22 12.0 1.6 2.2 1 0 0 1 1 1 0 HEAT-like repeat HEAT PF02985.22 CRK30536.1 - 0.06 13.6 3.3 0.12 12.7 0.4 3.2 4 0 0 4 4 4 0 HEAT repeat Lipase_GDSL_2 PF13472.6 CRK30538.1 - 9.8e-29 101.0 0.5 4.2e-18 66.4 0.3 2.4 2 1 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 CRK30538.1 - 2.6e-19 70.0 0.0 2.7e-14 53.6 0.0 2.1 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase CitT PF12431.8 CRK30538.1 - 0.014 15.7 0.3 93 3.5 0.0 4.2 4 0 0 4 4 4 0 Transcriptional regulator KAsynt_C_assoc PF16197.5 CRK30538.1 - 0.045 14.2 0.0 35 4.9 0.0 3.0 3 0 0 3 3 3 0 Ketoacyl-synthetase C-terminal extension BP28CT PF08146.12 CRK30540.1 - 1.7e-42 145.0 0.9 7.4e-42 142.9 0.9 2.2 1 0 0 1 1 1 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 CRK30540.1 - 5.3e-27 94.5 4.1 2.6e-26 92.2 0.0 4.3 4 0 0 4 4 4 1 U3 small nucleolar RNA-associated protein 10 HEAT PF02985.22 CRK30540.1 - 0.00016 21.6 11.0 0.56 10.6 0.4 6.7 6 0 0 6 6 6 2 HEAT repeat Vac14_Fab1_bd PF12755.7 CRK30540.1 - 0.057 14.0 0.0 4.8 7.8 0.0 3.1 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 CRK30540.1 - 0.32 11.4 17.8 0.53 10.7 0.9 5.6 5 0 0 5 5 5 0 HEAT repeats RTP1_C1 PF10363.9 CRK30540.1 - 2.5 8.3 5.4 1.9 8.7 0.0 3.7 5 0 0 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 CRK30540.1 - 6.8 7.3 17.7 0.58 10.7 1.7 5.8 5 1 0 5 5 5 0 HEAT-like repeat Pyr_redox_2 PF07992.14 CRK30542.1 - 1.8e-44 152.2 0.0 4.7e-43 147.5 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase BP28CT PF08146.12 CRK30542.1 - 1.3e-19 70.6 0.0 3.3e-19 69.3 0.0 1.7 1 0 0 1 1 1 1 BP28CT (NUC211) domain Pyr_redox PF00070.27 CRK30542.1 - 6.4e-12 45.9 0.0 1.8e-09 38.0 0.0 3.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CRK30542.1 - 0.0063 15.6 1.5 0.48 9.5 0.0 3.2 3 1 1 4 4 4 1 FAD binding domain RTP1_C1 PF10363.9 CRK30542.1 - 0.01 16.0 0.2 0.8 9.9 0.0 3.3 3 1 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Pyr_redox_3 PF13738.6 CRK30542.1 - 0.015 14.6 0.0 5.3 6.2 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CRK30542.1 - 0.024 14.8 0.0 22 5.4 0.0 3.6 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain HEAT PF02985.22 CRK30542.1 - 0.041 14.1 10.0 0.8 10.1 0.1 5.5 6 0 0 6 6 6 0 HEAT repeat RPOL_N PF14700.6 CRK30542.1 - 0.15 11.4 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal HEAT_2 PF13646.6 CRK30542.1 - 2.2 8.7 12.4 0.22 12.0 0.9 4.2 4 0 0 4 4 4 0 HEAT repeats AAA_5 PF07728.14 CRK30543.1 - 9.7e-121 398.1 0.0 4.8e-21 75.2 0.0 9.5 7 2 2 9 9 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 CRK30543.1 - 8.1e-51 170.7 6.0 5.6e-22 78.0 0.3 5.3 4 0 0 4 4 4 3 Midasin AAA lid domain AAA_7 PF12775.7 CRK30543.1 - 5.9e-29 100.9 1.8 1.5e-05 24.6 0.0 6.9 6 1 0 6 6 6 4 P-loop containing dynein motor region AAA_3 PF07726.11 CRK30543.1 - 1.4e-28 99.3 0.0 2e-09 37.4 0.0 7.5 7 0 0 7 7 7 3 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 CRK30543.1 - 1.2e-26 93.7 0.1 0.00015 22.2 0.0 7.2 6 0 0 6 6 6 5 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CRK30543.1 - 2.8e-26 92.9 22.7 0.00016 22.1 0.1 10.5 9 2 0 9 9 6 5 AAA ATPase domain AAA_lid_5 PF17865.1 CRK30543.1 - 3.3e-25 88.2 0.0 5e-24 84.4 0.0 2.9 2 0 0 2 2 2 1 Midasin AAA lid domain Dynein_heavy PF03028.15 CRK30543.1 - 4.3e-24 84.9 0.0 0.0032 17.5 0.0 7.7 7 1 0 7 7 6 5 Dynein heavy chain region D6 P-loop domain AAA_22 PF13401.6 CRK30543.1 - 2.8e-23 82.7 5.8 0.0022 18.3 0.0 9.0 7 1 0 7 7 6 5 AAA domain AAA_18 PF13238.6 CRK30543.1 - 4.9e-19 69.2 0.2 0.029 14.9 0.0 7.2 6 0 0 6 6 6 3 AAA domain AAA_33 PF13671.6 CRK30543.1 - 6.2e-19 68.6 0.0 0.13 12.4 0.0 7.4 6 0 0 6 6 6 5 AAA domain AAA_6 PF12774.7 CRK30543.1 - 2.5e-17 62.9 0.0 0.05 12.6 0.1 8.2 7 1 0 7 7 7 3 Hydrolytic ATP binding site of dynein motor region NACHT PF05729.12 CRK30543.1 - 7e-17 61.8 3.0 0.0036 17.2 0.0 6.3 5 0 0 5 5 5 4 NACHT domain Sigma54_activat PF00158.26 CRK30543.1 - 2.4e-15 56.7 0.0 0.031 14.0 0.1 6.4 6 0 0 6 6 6 2 Sigma-54 interaction domain AAA_14 PF13173.6 CRK30543.1 - 3.8e-15 56.1 0.0 0.013 15.6 0.0 7.2 7 0 0 7 7 6 2 AAA domain TsaE PF02367.17 CRK30543.1 - 6.7e-15 55.2 3.5 0.017 15.1 0.1 6.2 6 0 0 6 6 6 3 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 CRK30543.1 - 8.1e-14 52.3 8.1 0.024 15.1 0.0 7.6 7 0 0 7 7 6 2 ABC transporter RNA_helicase PF00910.22 CRK30543.1 - 2.8e-13 50.2 1.2 0.11 12.9 0.0 6.8 6 0 0 6 6 6 2 RNA helicase Zeta_toxin PF06414.12 CRK30543.1 - 7e-11 41.8 8.2 0.084 12.1 0.0 7.2 7 0 0 7 7 7 2 Zeta toxin Sigma54_activ_2 PF14532.6 CRK30543.1 - 9.8e-11 41.9 0.6 0.0035 17.4 0.0 5.8 6 0 0 6 6 5 2 Sigma-54 interaction domain T2SSE PF00437.20 CRK30543.1 - 1.3e-10 40.8 0.7 1.6 7.7 0.0 6.6 6 0 0 6 6 6 1 Type II/IV secretion system protein RsgA_GTPase PF03193.16 CRK30543.1 - 1.3e-10 41.4 3.1 0.42 10.5 0.1 6.2 6 0 0 6 6 6 2 RsgA GTPase Rad17 PF03215.15 CRK30543.1 - 1.5e-10 41.3 1.8 0.2 11.6 0.0 6.4 6 0 0 6 6 6 2 Rad17 P-loop domain RuvB_N PF05496.12 CRK30543.1 - 1.9e-10 40.7 2.2 0.032 14.0 0.0 5.9 6 0 0 6 6 6 2 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 CRK30543.1 - 2e-10 41.1 4.5 0.36 11.0 0.1 7.0 6 0 0 6 6 6 1 AAA domain AAA_25 PF13481.6 CRK30543.1 - 5.4e-10 39.2 2.8 0.68 9.5 0.0 6.5 6 0 0 6 6 6 2 AAA domain AAA_19 PF13245.6 CRK30543.1 - 1.5e-09 38.3 6.3 4.5 7.6 0.0 6.4 6 0 0 6 6 5 0 AAA domain AAA_29 PF13555.6 CRK30543.1 - 1.5e-09 37.4 2.1 1.1 9.1 0.0 6.6 6 0 0 6 6 6 1 P-loop containing region of AAA domain Mg_chelatase PF01078.21 CRK30543.1 - 1.6e-09 37.5 5.6 1.2 8.4 0.1 9.1 10 0 0 10 10 9 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 CRK30543.1 - 2.4e-08 33.9 0.6 0.93 9.2 0.0 6.0 6 0 0 6 6 6 1 IstB-like ATP binding protein ATPase_2 PF01637.18 CRK30543.1 - 7.9e-08 32.5 0.0 1.3 8.9 0.0 6.2 6 0 0 6 6 6 1 ATPase domain predominantly from Archaea TniB PF05621.11 CRK30543.1 - 8e-08 31.9 0.3 0.89 8.9 0.0 5.9 6 0 0 6 6 5 1 Bacterial TniB protein Viral_helicase1 PF01443.18 CRK30543.1 - 9.8e-08 32.0 0.9 0.41 10.4 0.0 6.1 6 0 0 6 6 6 1 Viral (Superfamily 1) RNA helicase SRP54 PF00448.22 CRK30543.1 - 1.3e-07 31.5 3.2 0.44 10.2 0.1 5.1 5 0 0 5 5 4 2 SRP54-type protein, GTPase domain AAA_24 PF13479.6 CRK30543.1 - 1.7e-07 31.1 0.8 3.1 7.5 0.1 6.4 6 1 0 6 6 6 0 AAA domain NTPase_1 PF03266.15 CRK30543.1 - 1.6e-06 28.1 6.7 1.2 9.0 0.1 6.1 6 0 0 6 6 5 1 NTPase PduV-EutP PF10662.9 CRK30543.1 - 2.8e-06 27.1 4.2 0.058 13.1 0.0 5.4 7 0 0 7 7 4 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 CRK30543.1 - 1.3e-05 25.2 2.1 22 5.1 0.0 6.5 6 0 0 6 6 5 0 50S ribosome-binding GTPase Roc PF08477.13 CRK30543.1 - 1.8e-05 25.0 2.2 3.6 7.8 0.0 6.0 6 0 0 6 6 5 0 Ras of Complex, Roc, domain of DAPkinase DUF815 PF05673.13 CRK30543.1 - 2.6e-05 23.5 3.4 4.7 6.3 0.0 5.1 6 0 0 6 6 4 0 Protein of unknown function (DUF815) CbiA PF01656.23 CRK30543.1 - 2.8e-05 24.2 0.3 4.2 7.4 0.0 4.5 4 0 0 4 4 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain ResIII PF04851.15 CRK30543.1 - 3.3e-05 24.0 0.6 4.9 7.1 0.0 4.9 4 0 0 4 4 4 0 Type III restriction enzyme, res subunit cobW PF02492.19 CRK30543.1 - 8.6e-05 22.2 6.6 7.2 6.2 0.0 6.0 6 0 0 6 6 6 0 CobW/HypB/UreG, nucleotide-binding domain TIP49 PF06068.13 CRK30543.1 - 0.00019 20.7 2.0 13 4.8 0.0 5.0 6 0 0 6 6 5 0 TIP49 P-loop domain AAA_17 PF13207.6 CRK30543.1 - 0.00024 21.5 7.7 3 8.3 0.0 6.1 5 0 0 5 5 5 0 AAA domain AAA_9 PF12781.7 CRK30543.1 - 0.00028 20.1 0.0 0.011 14.9 0.0 3.5 4 0 0 4 4 3 1 ATP-binding dynein motor region ATPase PF06745.13 CRK30543.1 - 0.0004 19.8 0.7 23 4.2 0.0 5.4 5 0 0 5 5 5 0 KaiC Thymidylate_kin PF02223.17 CRK30543.1 - 0.0011 18.7 0.2 2.8 7.6 0.0 5.1 5 0 0 5 5 4 0 Thymidylate kinase dNK PF01712.19 CRK30543.1 - 0.0019 18.1 7.3 17 5.2 0.0 5.5 6 0 0 6 6 5 0 Deoxynucleoside kinase ATP_bind_1 PF03029.17 CRK30543.1 - 0.002 18.0 6.6 9.3 5.9 0.1 5.7 6 0 0 6 6 6 0 Conserved hypothetical ATP binding protein DAP3 PF10236.9 CRK30543.1 - 0.0021 17.3 4.0 5.3 6.1 0.0 5.0 5 0 0 5 5 5 0 Mitochondrial ribosomal death-associated protein 3 KTI12 PF08433.10 CRK30543.1 - 0.0084 15.6 1.2 3.4 7.0 0.0 4.9 6 0 0 6 6 5 0 Chromatin associated protein KTI12 MeaB PF03308.16 CRK30543.1 - 0.0093 15.0 1.6 2.4 7.1 0.2 3.4 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CPT PF07931.12 CRK30543.1 - 0.017 15.0 5.6 26 4.6 0.0 6.3 7 1 0 7 7 4 0 Chloramphenicol phosphotransferase-like protein PRK PF00485.18 CRK30543.1 - 0.028 14.2 6.0 5.8 6.6 0.0 5.3 7 0 0 7 7 4 0 Phosphoribulokinase / Uridine kinase family SKI PF01202.22 CRK30543.1 - 0.031 14.4 1.1 3.7 7.7 0.0 4.0 4 0 0 4 4 3 0 Shikimate kinase ATP-synt_ab PF00006.25 CRK30543.1 - 0.036 13.7 0.0 20 4.7 0.0 3.4 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain DEAD PF00270.29 CRK30543.1 - 0.039 13.7 1.7 11 5.8 0.1 4.1 4 0 0 4 4 3 0 DEAD/DEAH box helicase Ploopntkinase3 PF18751.1 CRK30543.1 - 0.046 13.6 0.6 19 5.1 0.0 4.5 5 0 0 5 5 4 0 P-loop Nucleotide Kinase3 AAA_31 PF13614.6 CRK30543.1 - 0.058 13.3 3.0 3.5 7.5 0.0 4.0 4 0 0 4 4 4 0 AAA domain Septin PF00735.18 CRK30543.1 - 0.2 10.9 0.7 23 4.2 0.0 3.9 4 0 0 4 4 4 0 Septin Cytidylate_kin PF02224.18 CRK30543.1 - 0.33 10.7 6.4 49 3.6 0.3 5.2 6 0 0 6 6 5 0 Cytidylate kinase MobB PF03205.14 CRK30543.1 - 0.96 9.3 3.8 46 3.9 0.1 4.6 6 0 0 6 6 4 0 Molybdopterin guanine dinucleotide synthesis protein B FAA_hydro_N_2 PF18288.1 CRK30543.1 - 2.5 8.6 4.5 12 6.4 0.7 4.0 3 0 0 3 3 2 0 Fumarylacetoacetase N-terminal domain 2 AAA_23 PF13476.6 CRK30543.1 - 2.6 8.5 39.4 1.1 9.7 0.0 8.6 9 0 0 9 9 5 0 AAA domain Ribosomal_L12 PF00542.19 CRK30544.1 - 5.6e-23 81.1 4.5 4.2e-22 78.3 3.2 2.2 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 CRK30544.1 - 1.5e-13 50.2 7.9 1.5e-13 50.2 7.9 3.6 4 1 0 4 4 4 1 Ribosomal protein L7/L12 dimerisation domain CTK3 PF12243.8 CRK30545.1 - 2.6e-43 147.0 1.8 4.2e-43 146.3 1.8 1.3 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 CRK30545.1 - 2.7e-18 65.9 12.3 2.7e-18 65.9 12.3 2.0 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 C-terminus Hat1_N PF10394.9 CRK30546.1 - 7.9e-51 172.5 0.1 1.9e-50 171.2 0.0 1.6 2 0 0 2 2 2 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.25 CRK30546.1 - 0.0005 20.3 0.0 0.001 19.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CRK30546.1 - 0.0024 17.8 0.0 0.0053 16.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CRK30546.1 - 0.042 14.3 0.0 0.097 13.1 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CRK30546.1 - 0.15 12.2 0.0 0.37 10.9 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Zip PF02535.22 CRK30547.1 - 2.2e-36 125.8 17.2 2.8e-27 95.8 6.7 3.1 3 0 0 3 3 3 3 ZIP Zinc transporter WD40 PF00400.32 CRK30548.1 - 3.4e-36 122.6 25.2 6.7e-07 29.9 0.4 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.7 CRK30548.1 - 5.8e-11 42.1 0.9 1.2e-10 41.1 0.9 1.6 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 CRK30548.1 - 3e-08 33.8 3.1 0.13 12.5 0.0 5.8 1 1 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CRK30548.1 - 1.5e-05 23.9 8.4 0.17 10.5 0.1 5.9 1 1 4 6 6 6 1 Nucleoporin Nup120/160 F-box PF00646.33 CRK30548.1 - 0.00014 21.7 2.3 0.00031 20.5 2.3 1.7 1 0 0 1 1 1 1 F-box domain WD40_like PF17005.5 CRK30548.1 - 0.025 13.9 0.0 0.47 9.7 0.0 2.4 1 1 1 2 2 2 0 WD40-like domain PQQ_2 PF13360.6 CRK30548.1 - 0.079 12.5 3.3 4.6 6.8 3.5 3.3 1 1 1 2 2 2 0 PQQ-like domain PQQ_3 PF13570.6 CRK30548.1 - 0.092 13.3 5.4 14 6.4 0.0 5.2 7 0 0 7 7 7 0 PQQ-like domain DUF3983 PF13137.6 CRK30548.1 - 0.097 12.5 0.2 0.32 10.9 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3983) Pex14_N PF04695.13 CRK30548.1 - 2.5 8.7 5.6 2 9.0 0.3 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Voltage_CLC PF00654.20 CRK30549.1 - 1.1e-64 219.0 19.5 1.1e-64 219.0 19.5 1.4 2 0 0 2 2 2 1 Voltage gated chloride channel DUF4644 PF15486.6 CRK30549.1 - 7.2 6.3 8.3 0.91 9.3 0.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4644) Neurochondrin PF05536.11 CRK30551.1 - 3.2e-56 191.0 0.0 4e-56 190.6 0.0 1.1 1 0 0 1 1 1 1 Neurochondrin Trypan_PARP PF05887.11 CRK30552.1 - 0.02 14.9 4.1 0.027 14.4 4.1 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF241 PF03087.14 CRK30552.1 - 0.22 11.3 0.6 3.5 7.4 0.0 2.1 2 0 0 2 2 2 0 Arabidopsis protein of unknown function U1snRNP70_N PF12220.8 CRK30552.1 - 0.58 10.8 6.7 1.2 9.8 0.1 2.2 1 1 1 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal YqzE PF14038.6 CRK30552.1 - 0.61 10.1 1.8 1.9 8.6 0.1 2.2 2 0 0 2 2 2 0 YqzE-like protein Ras PF00071.22 CRK30553.1 - 3e-52 176.5 0.0 3.6e-52 176.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CRK30553.1 - 6.2e-19 68.4 0.0 8.9e-19 67.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CRK30553.1 - 2.7e-06 26.9 0.0 3.9e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CRK30553.1 - 0.15 11.6 0.2 0.9 9.0 0.0 2.1 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Arginase PF00491.21 CRK30554.1 - 1.5e-35 123.1 0.0 1.9e-35 122.7 0.0 1.1 1 0 0 1 1 1 1 Arginase family AAA_5 PF07728.14 CRK30555.1 - 5.4e-121 399.0 0.0 4.8e-21 75.2 0.0 9.6 8 1 1 9 9 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 CRK30555.1 - 7.3e-50 167.6 5.2 9.3e-22 77.2 0.1 5.2 4 0 0 4 4 4 3 Midasin AAA lid domain AAA_7 PF12775.7 CRK30555.1 - 9.2e-31 106.8 2.1 2.6e-06 27.1 0.0 6.9 6 1 0 6 6 6 5 P-loop containing dynein motor region AAA_lid_5 PF17865.1 CRK30555.1 - 1.2e-30 105.7 0.1 1.6e-29 102.1 0.0 2.9 2 0 0 2 2 2 1 Midasin AAA lid domain AAA_3 PF07726.11 CRK30555.1 - 5.2e-29 100.8 0.0 2.1e-09 37.3 0.0 7.4 7 0 0 7 7 7 3 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CRK30555.1 - 1.8e-28 100.1 19.3 9.4e-05 22.8 0.1 10.2 8 2 0 8 8 6 5 AAA ATPase domain AAA PF00004.29 CRK30555.1 - 5.5e-27 94.8 0.3 0.00015 22.2 0.0 7.2 6 0 0 6 6 6 5 ATPase family associated with various cellular activities (AAA) Dynein_heavy PF03028.15 CRK30555.1 - 6.9e-25 87.5 0.0 0.0011 19.0 0.0 8.0 8 1 0 8 8 6 5 Dynein heavy chain region D6 P-loop domain AAA_22 PF13401.6 CRK30555.1 - 4.1e-23 82.2 3.2 0.0055 17.0 0.0 8.5 6 1 0 6 6 6 5 AAA domain AAA_6 PF12774.7 CRK30555.1 - 4.9e-20 71.8 0.0 0.01 14.9 0.0 8.3 7 1 0 7 7 7 3 Hydrolytic ATP binding site of dynein motor region AAA_18 PF13238.6 CRK30555.1 - 4e-19 69.5 0.3 0.031 14.8 0.0 7.3 6 0 0 6 6 6 3 AAA domain AAA_33 PF13671.6 CRK30555.1 - 1.2e-18 67.6 1.1 0.13 12.4 0.0 7.9 7 0 0 7 7 6 5 AAA domain Sigma54_activat PF00158.26 CRK30555.1 - 2.4e-17 63.1 0.0 0.022 14.5 0.1 6.4 6 0 0 6 6 6 3 Sigma-54 interaction domain AAA_14 PF13173.6 CRK30555.1 - 4.1e-16 59.2 0.0 0.01 15.8 0.0 7.4 7 1 0 7 7 6 3 AAA domain AAA_30 PF13604.6 CRK30555.1 - 9.2e-16 58.1 0.0 0.19 11.4 0.0 7.9 7 1 0 7 7 6 2 AAA domain ABC_tran PF00005.27 CRK30555.1 - 1.2e-15 58.2 3.0 0.023 15.2 0.0 7.5 6 0 0 6 6 6 2 ABC transporter TsaE PF02367.17 CRK30555.1 - 2.1e-15 56.8 4.2 0.011 15.7 0.2 6.2 6 0 0 6 6 6 3 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 CRK30555.1 - 3.4e-15 56.4 3.1 0.12 12.2 0.1 6.2 5 0 0 5 5 5 4 NACHT domain RNA_helicase PF00910.22 CRK30555.1 - 1.1e-13 51.5 1.3 0.11 12.9 0.0 6.7 6 0 0 6 6 6 2 RNA helicase T2SSE PF00437.20 CRK30555.1 - 1.7e-13 50.3 0.6 0.062 12.4 0.0 6.5 6 0 0 6 6 6 2 Type II/IV secretion system protein RuvB_N PF05496.12 CRK30555.1 - 6.9e-13 48.7 1.0 0.033 13.9 0.0 6.4 6 0 0 6 6 6 2 Holliday junction DNA helicase RuvB P-loop domain Zeta_toxin PF06414.12 CRK30555.1 - 2.6e-12 46.4 7.2 0.024 13.9 0.0 7.1 7 0 0 7 7 7 2 Zeta toxin Sigma54_activ_2 PF14532.6 CRK30555.1 - 3.2e-12 46.7 0.4 0.0036 17.4 0.0 6.1 6 0 0 6 6 5 2 Sigma-54 interaction domain RsgA_GTPase PF03193.16 CRK30555.1 - 2.5e-11 43.8 3.6 0.38 10.6 0.2 6.3 6 0 0 6 6 6 2 RsgA GTPase Rad17 PF03215.15 CRK30555.1 - 2.7e-11 43.7 2.0 0.2 11.5 0.0 6.4 6 0 0 6 6 6 2 Rad17 P-loop domain AAA_19 PF13245.6 CRK30555.1 - 1.6e-10 41.5 4.4 2.3 8.5 0.0 6.5 6 0 0 6 6 5 1 AAA domain AAA_28 PF13521.6 CRK30555.1 - 5.6e-10 39.7 5.5 0.37 11.0 0.1 7.0 6 0 0 6 6 6 1 AAA domain AAA_29 PF13555.6 CRK30555.1 - 8.6e-10 38.2 1.5 1 9.1 0.0 6.6 6 0 0 6 6 6 1 P-loop containing region of AAA domain Mg_chelatase PF01078.21 CRK30555.1 - 1.2e-09 37.8 3.2 5.5 6.3 0.1 9.1 9 0 0 9 9 9 0 Magnesium chelatase, subunit ChlI ATPase_2 PF01637.18 CRK30555.1 - 1.4e-09 38.2 0.0 0.76 9.6 0.0 6.3 6 0 0 6 6 6 1 ATPase domain predominantly from Archaea AAA_25 PF13481.6 CRK30555.1 - 1.8e-09 37.4 3.1 0.69 9.5 0.0 5.7 5 0 0 5 5 5 2 AAA domain IstB_IS21 PF01695.17 CRK30555.1 - 3.5e-09 36.6 0.3 0.95 9.2 0.0 6.3 6 0 0 6 6 6 1 IstB-like ATP binding protein TniB PF05621.11 CRK30555.1 - 8.1e-09 35.2 0.3 0.89 8.9 0.0 6.2 6 0 0 6 6 5 1 Bacterial TniB protein AAA_24 PF13479.6 CRK30555.1 - 2.2e-08 34.1 1.5 2.2 7.9 0.1 6.5 6 1 1 7 7 6 1 AAA domain Viral_helicase1 PF01443.18 CRK30555.1 - 6e-08 32.7 0.7 0.37 10.5 0.0 6.1 6 0 0 6 6 6 1 Viral (Superfamily 1) RNA helicase SRP54 PF00448.22 CRK30555.1 - 2e-07 30.9 3.6 0.61 9.7 0.1 5.0 5 0 0 5 5 4 2 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 CRK30555.1 - 4.8e-07 29.9 5.2 1.9 8.4 0.1 6.1 6 0 0 6 6 5 1 NTPase PduV-EutP PF10662.9 CRK30555.1 - 4.7e-06 26.4 4.6 0.059 13.1 0.0 5.5 7 0 0 7 7 4 1 Ethanolamine utilisation - propanediol utilisation ResIII PF04851.15 CRK30555.1 - 4.8e-06 26.7 1.5 5 7.1 0.0 5.5 5 0 0 5 5 5 0 Type III restriction enzyme, res subunit CbiA PF01656.23 CRK30555.1 - 2.3e-05 24.4 0.5 4.2 7.4 0.0 4.8 4 0 0 4 4 4 0 CobQ/CobB/MinD/ParA nucleotide binding domain Roc PF08477.13 CRK30555.1 - 2.4e-05 24.6 2.2 8.2 6.7 0.1 6.1 6 0 0 6 6 5 0 Ras of Complex, Roc, domain of DAPkinase TIP49 PF06068.13 CRK30555.1 - 3.5e-05 23.2 1.4 14 4.8 0.0 5.2 6 0 0 6 6 6 0 TIP49 P-loop domain DUF815 PF05673.13 CRK30555.1 - 5e-05 22.6 5.8 4.8 6.3 0.0 5.2 6 0 0 6 6 5 0 Protein of unknown function (DUF815) MMR_HSR1 PF01926.23 CRK30555.1 - 5.4e-05 23.3 2.6 41 4.3 0.0 6.4 6 0 0 6 6 5 0 50S ribosome-binding GTPase cobW PF02492.19 CRK30555.1 - 0.00012 21.7 7.4 7.4 6.1 0.0 6.0 6 0 0 6 6 6 0 CobW/HypB/UreG, nucleotide-binding domain AAA_9 PF12781.7 CRK30555.1 - 0.0003 20.0 0.0 0.023 13.8 0.0 3.9 4 0 0 4 4 3 1 ATP-binding dynein motor region DAP3 PF10236.9 CRK30555.1 - 0.00046 19.5 4.8 5.4 6.1 0.0 5.4 5 0 0 5 5 5 0 Mitochondrial ribosomal death-associated protein 3 AAA_17 PF13207.6 CRK30555.1 - 0.00054 20.4 8.5 3.1 8.2 0.0 6.0 5 0 0 5 5 5 0 AAA domain ATPase PF06745.13 CRK30555.1 - 0.00083 18.8 0.1 27 4.0 0.0 4.9 4 0 0 4 4 4 0 KaiC Thymidylate_kin PF02223.17 CRK30555.1 - 0.0012 18.6 0.3 2.8 7.6 0.0 5.1 5 0 0 5 5 4 0 Thymidylate kinase dNK PF01712.19 CRK30555.1 - 0.0017 18.3 7.5 17 5.1 0.0 5.6 6 0 0 6 6 5 0 Deoxynucleoside kinase ATP_bind_1 PF03029.17 CRK30555.1 - 0.0022 17.8 6.9 9.5 5.9 0.1 5.7 6 0 0 6 6 6 0 Conserved hypothetical ATP binding protein PRK PF00485.18 CRK30555.1 - 0.0026 17.5 1.1 5.7 6.6 0.0 4.8 6 0 0 6 6 4 0 Phosphoribulokinase / Uridine kinase family KTI12 PF08433.10 CRK30555.1 - 0.0079 15.7 0.0 1.6 8.1 0.0 4.1 4 0 0 4 4 4 1 Chromatin associated protein KTI12 NB-ARC PF00931.22 CRK30555.1 - 0.01 15.1 6.8 32 3.6 1.0 5.6 5 1 0 5 5 5 0 NB-ARC domain MeaB PF03308.16 CRK30555.1 - 0.012 14.7 1.8 3.7 6.4 0.2 3.5 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATP-synt_ab PF00006.25 CRK30555.1 - 0.014 15.1 0.0 16 5.0 0.0 3.4 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain Bac_DnaA PF00308.18 CRK30555.1 - 0.022 14.6 2.0 18 5.1 0.0 5.0 6 0 0 6 6 5 0 Bacterial dnaA protein DEAD PF00270.29 CRK30555.1 - 0.029 14.2 1.4 11 5.8 0.1 4.3 5 0 0 5 5 3 0 DEAD/DEAH box helicase Ploopntkinase3 PF18751.1 CRK30555.1 - 0.032 14.1 0.8 19 5.1 0.0 4.7 6 0 0 6 6 4 0 P-loop Nucleotide Kinase3 CPT PF07931.12 CRK30555.1 - 0.033 14.0 7.1 27 4.5 0.0 6.5 7 1 0 7 7 4 0 Chloramphenicol phosphotransferase-like protein SKI PF01202.22 CRK30555.1 - 0.036 14.2 1.5 3.7 7.6 0.0 4.0 4 0 0 4 4 3 0 Shikimate kinase PhoH PF02562.16 CRK30555.1 - 0.15 11.5 0.2 43 3.5 0.0 4.1 4 0 0 4 4 4 0 PhoH-like protein Cytidylate_kin PF02224.18 CRK30555.1 - 0.17 11.6 5.8 49 3.5 0.3 5.2 6 0 0 6 6 5 0 Cytidylate kinase Septin PF00735.18 CRK30555.1 - 0.34 10.1 2.0 17 4.5 0.0 3.9 5 0 0 5 5 4 0 Septin AAA_23 PF13476.6 CRK30555.1 - 1.3 9.5 39.3 1.1 9.7 0.0 8.7 9 0 0 9 9 5 0 AAA domain AAA_31 PF13614.6 CRK30555.1 - 1.5 8.7 3.6 91 2.9 0.0 4.1 4 0 0 4 4 4 0 AAA domain Ribosomal_L12 PF00542.19 CRK30556.1 - 3.6e-22 78.5 5.0 2.2e-21 76.0 3.6 2.2 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 CRK30556.1 - 7.9e-12 44.7 13.3 7.9e-12 44.7 13.3 3.7 4 1 0 4 4 4 1 Ribosomal protein L7/L12 dimerisation domain CTK3 PF12243.8 CRK30557.1 - 2.6e-43 146.9 1.8 4.2e-43 146.3 1.8 1.3 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 CRK30557.1 - 2.2e-18 66.2 12.2 2.2e-18 66.2 12.2 2.0 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 C-terminus Luciferase_N PF05295.11 CRK30557.1 - 0.15 12.1 0.0 2.3 8.3 0.0 2.7 2 1 1 3 3 3 0 Luciferase/LBP N-terminal domain Hat1_N PF10394.9 CRK30558.1 - 4.5e-51 173.3 0.1 1.4e-50 171.6 0.0 1.7 2 0 0 2 2 2 1 Histone acetyl transferase HAT1 N-terminus Zip PF02535.22 CRK30559.1 - 6.9e-36 124.1 18.1 1.8e-27 96.5 5.9 3.1 3 0 0 3 3 3 3 ZIP Zinc transporter WD40 PF00400.32 CRK30560.1 - 1.2e-36 124.1 22.6 7.6e-07 29.7 0.4 7.1 6 0 0 6 6 6 6 WD domain, G-beta repeat F-box-like PF12937.7 CRK30560.1 - 1.3e-10 41.0 1.0 2.6e-10 40.0 1.0 1.5 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 CRK30560.1 - 4.8e-08 33.2 2.7 0.027 14.8 0.0 5.7 1 1 4 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CRK30560.1 - 4.7e-05 22.2 9.2 0.19 10.3 0.2 5.8 1 1 5 6 6 6 1 Nucleoporin Nup120/160 F-box PF00646.33 CRK30560.1 - 0.0014 18.5 2.5 0.0031 17.3 2.5 1.7 1 0 0 1 1 1 1 F-box domain BBS2_Mid PF14783.6 CRK30560.1 - 0.0076 16.3 0.1 3.1 7.9 0.0 3.3 3 1 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region WD40_like PF17005.5 CRK30560.1 - 0.035 13.4 0.0 0.53 9.6 0.0 2.3 1 1 1 2 2 2 0 WD40-like domain PQQ_2 PF13360.6 CRK30560.1 - 0.13 11.9 3.6 2.1 7.9 1.8 3.3 1 1 0 1 1 1 0 PQQ-like domain DUF3983 PF13137.6 CRK30560.1 - 0.13 12.1 0.2 0.35 10.7 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3983) PQQ_3 PF13570.6 CRK30560.1 - 0.22 12.1 5.9 15 6.2 0.0 5.1 7 0 0 7 7 7 0 PQQ-like domain E1_dh PF00676.20 CRK30561.1 - 8.3e-114 379.6 0.6 1e-113 379.2 0.6 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 CRK30561.1 - 0.0017 17.6 0.0 0.0033 16.7 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase DNA_ligase_A_M PF01068.21 CRK30562.1 - 1.6e-59 201.0 0.9 3.8e-47 160.6 0.3 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 CRK30562.1 - 1.5e-44 152.4 0.2 4.3e-44 150.9 0.0 1.9 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 CRK30562.1 - 5.6e-29 100.7 0.0 2.2e-28 98.7 0.0 2.1 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 CRK30562.1 - 9.7e-05 22.7 0.1 0.00016 22.0 0.1 1.4 1 0 0 1 1 1 1 RNA ligase Voltage_CLC PF00654.20 CRK30563.1 - 4.8e-86 289.2 28.5 8.4e-86 288.4 28.5 1.4 1 0 0 1 1 1 1 Voltage gated chloride channel LacI PF00356.21 CRK30563.1 - 0.38 10.6 1.4 0.82 9.5 1.4 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family DUF4644 PF15486.6 CRK30563.1 - 4 7.2 7.0 0.59 9.9 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4644) Neurochondrin PF05536.11 CRK30564.1 - 1.7e-80 271.1 0.0 2.3e-80 270.7 0.0 1.1 1 0 0 1 1 1 1 Neurochondrin tRNA-synt_2 PF00152.20 CRK30566.1 - 1.7e-86 290.2 0.0 2.5e-86 289.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CRK30566.1 - 4.4e-09 36.2 0.0 7.4e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.6 CRK30566.1 - 0.072 13.3 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Arginase PF00491.21 CRK30567.1 - 1.4e-33 116.6 0.2 3.3e-33 115.4 0.2 1.5 1 0 0 1 1 1 1 Arginase family RRM PF10378.9 CRK30567.1 - 1.1e-08 34.7 8.7 1.1e-08 34.7 8.7 3.3 2 1 1 3 3 3 1 Putative RRM domain tRNA-synt_2 PF00152.20 CRK30569.1 - 4.5e-86 288.8 0.0 6.9e-86 288.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CRK30569.1 - 4.5e-09 36.2 0.0 7.5e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.6 CRK30569.1 - 0.066 13.4 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain RRM_1 PF00076.22 CRK30570.1 - 9.5e-37 124.7 0.1 4.2e-11 42.5 0.2 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CRK30570.1 - 3.7e-16 58.7 0.0 0.0068 16.2 0.0 4.3 4 0 0 4 4 4 4 Occluded RNA-recognition motif RRM PF10378.9 CRK30570.1 - 1.7e-06 27.6 13.9 1.7e-06 27.6 13.9 4.5 4 1 0 4 4 4 1 Putative RRM domain RRM_7 PF16367.5 CRK30570.1 - 4.6e-06 26.7 0.0 0.0081 16.3 0.0 3.5 3 0 0 3 3 3 2 RNA recognition motif DUF4523 PF15023.6 CRK30570.1 - 5e-06 26.4 0.0 0.009 15.8 0.0 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF4523) RRM_3 PF08777.11 CRK30570.1 - 0.0034 17.4 0.1 0.34 11.0 0.1 2.9 3 0 0 3 3 3 1 RNA binding motif RRM_Rrp7 PF17799.1 CRK30570.1 - 0.012 15.4 0.0 1.2 9.0 0.0 3.7 2 1 2 4 4 4 0 Rrp7 RRM-like N-terminal domain RNA_bind PF08675.11 CRK30570.1 - 0.056 13.5 0.6 0.28 11.2 0.0 2.4 3 0 0 3 3 3 0 RNA binding domain Nup35_RRM_2 PF14605.6 CRK30570.1 - 0.07 13.1 0.0 30 4.7 0.0 3.2 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif His_Phos_2 PF00328.22 CRK30571.1 - 1.6e-16 60.6 0.0 2e-15 57.1 0.0 2.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) LCAT PF02450.15 CRK30572.1 - 0.007 15.6 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 CRK30572.1 - 0.015 15.9 0.0 0.015 15.9 0.0 2.9 2 2 0 3 3 3 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CRK30572.1 - 0.041 13.1 0.0 0.072 12.3 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 CRK30572.1 - 0.042 13.7 0.0 0.08 12.8 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase Vac17 PF17321.2 CRK30572.1 - 0.11 12.0 0.2 0.17 11.3 0.2 1.2 1 0 0 1 1 1 0 Vacuole-related protein 17 DUF676 PF05057.14 CRK30572.1 - 0.18 11.3 0.0 0.36 10.3 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Peptidase_S9 PF00326.21 CRK30572.1 - 0.21 11.0 0.0 0.36 10.3 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family STAT1_TAZ2bind PF12162.8 CRK30573.1 - 0.12 11.9 0.1 0.23 11.1 0.1 1.4 1 0 0 1 1 1 0 STAT1 TAZ2 binding domain Gtr1_RagA PF04670.12 CRK30574.1 - 1.4e-70 237.3 0.1 1.7e-70 237.0 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 CRK30574.1 - 0.00079 18.9 0.0 0.0016 17.9 0.0 1.5 2 0 0 2 2 2 1 ADP-ribosylation factor family Roc PF08477.13 CRK30574.1 - 0.006 16.8 0.0 0.013 15.7 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 CRK30574.1 - 0.017 15.2 0.0 0.037 14.1 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CRK30574.1 - 0.02 14.4 0.0 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 CRK30574.1 - 0.036 14.4 0.0 0.091 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain ANAPC4 PF12896.7 CRK30575.1 - 1.7e-66 223.7 0.0 2.8e-66 222.9 0.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 CRK30575.1 - 4.6e-11 42.9 0.1 3.3e-10 40.1 0.0 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Zn_clus PF00172.18 CRK30575.1 - 3.2e-08 33.6 7.1 5.5e-08 32.8 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 CRK30575.1 - 3.8e-06 26.0 0.0 6.1e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain FKBP_N_2 PF18023.1 CRK30575.1 - 0.00019 21.5 0.0 0.19 11.8 0.0 2.7 2 0 0 2 2 2 2 BDBT FKBP like N-terminal T3SS_HrpK1 PF16937.5 CRK30575.1 - 0.0043 16.8 0.1 3 7.5 0.0 2.3 2 0 0 2 2 2 2 Type III secretion system translocator protein, HrpF WD40 PF00400.32 CRK30575.1 - 0.033 15.1 0.0 0.18 12.7 0.0 2.4 1 0 0 1 1 1 0 WD domain, G-beta repeat baeRF_family10 PF18854.1 CRK30575.1 - 1.5 9.0 9.7 4.7 7.5 0.2 3.7 3 0 0 3 3 3 0 Bacterial archaeo-eukaryotic release factor family 10 AA_permease_2 PF13520.6 CRK30576.1 - 1.8e-54 185.2 49.5 2.1e-54 185.0 49.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CRK30576.1 - 1.7e-15 56.6 37.4 2.3e-15 56.2 37.4 1.1 1 0 0 1 1 1 1 Amino acid permease Cu_amine_oxid PF01179.20 CRK30577.1 - 1.1e-148 495.5 0.0 1.3e-148 495.4 0.0 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain RINGv PF12906.7 CRK30577.1 - 0.017 15.2 0.1 6.7 6.9 0.0 2.6 2 0 0 2 2 2 0 RING-variant domain Adap_comp_sub PF00928.21 CRK30578.1 - 4.5e-17 62.3 0.0 5.8e-17 61.9 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CRK30578.1 - 9.2e-08 32.1 0.0 1.6e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RPM2 PF08579.11 CRK30578.1 - 0.0027 18.1 0.3 0.0061 17.0 0.3 1.6 1 0 0 1 1 1 1 Mitochondrial ribonuclease P subunit (RPM2) DUF2420 PF10336.9 CRK30579.1 - 9.3e-12 44.9 0.0 2e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) IlvGEDA_leader PF08046.11 CRK30580.1 - 2.2 7.8 9.1 2.2 7.8 3.1 2.6 2 0 0 2 2 2 0 IlvGEDA operon leader peptide Mg_trans_NIPA PF05653.14 CRK30581.1 - 3.9e-66 223.2 7.7 4.8e-66 222.9 7.7 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 CRK30581.1 - 5.5e-05 23.4 7.6 5.5e-05 23.4 7.6 3.1 3 0 0 3 3 3 2 EamA-like transporter family Myotub-related PF06602.14 CRK30585.1 - 2.2e-51 174.9 0.2 3.6e-51 174.1 0.2 1.3 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain MCPVI PF02993.14 CRK30585.1 - 0.077 12.8 0.1 0.077 12.8 0.1 2.0 2 0 0 2 2 2 0 Minor capsid protein VI Pox_I3 PF04661.12 CRK30585.1 - 0.23 10.5 0.0 0.38 9.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus I3 ssDNA-binding protein Myotub-related PF06602.14 CRK30587.1 - 1.5e-39 135.9 0.0 1.7e-39 135.7 0.0 1.0 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain tRNA_synthFbeta PF17759.1 CRK30588.1 - 9.8e-47 159.1 0.0 1.6e-46 158.5 0.0 1.3 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 CRK30588.1 - 1.5e-30 105.2 0.7 2.1e-29 101.5 0.2 2.4 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 CRK30588.1 - 1.9e-26 92.8 0.0 3.1e-26 92.1 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 CRK30588.1 - 3.5e-14 52.8 0.0 4.5e-11 42.9 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetase B5 domain HEAT PF02985.22 CRK30589.1 - 4.8e-38 125.9 16.6 0.01 16.0 0.1 12.3 13 0 0 13 13 13 10 HEAT repeat HEAT_2 PF13646.6 CRK30589.1 - 9.9e-33 112.4 7.7 2.4e-10 40.7 0.0 7.5 3 2 4 7 7 7 7 HEAT repeats HEAT_EZ PF13513.6 CRK30589.1 - 3e-11 43.6 4.9 0.063 13.8 0.1 7.7 8 1 1 9 9 9 2 HEAT-like repeat Cnd1 PF12717.7 CRK30589.1 - 1.6e-10 41.3 8.6 0.0048 17.0 0.2 5.8 4 1 1 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 CRK30589.1 - 1.4e-08 35.2 5.2 0.0048 17.5 0.1 6.5 3 1 5 8 8 8 1 Vacuolar 14 Fab1-binding region RTP1_C1 PF10363.9 CRK30589.1 - 5.7e-08 32.9 5.2 0.17 12.0 0.1 5.5 5 1 1 6 6 6 3 Required for nuclear transport of RNA pol II C-terminus 1 Adaptin_N PF01602.20 CRK30589.1 - 4.7e-06 25.5 7.8 0.0022 16.7 0.2 4.9 3 2 3 6 6 6 2 Adaptin N terminal region CLASP_N PF12348.8 CRK30589.1 - 0.0027 17.3 3.0 0.094 12.3 0.2 4.0 2 2 1 4 4 4 1 CLASP N terminal M11L PF11099.8 CRK30589.1 - 0.0042 17.4 0.3 7.5 6.8 0.0 3.5 3 1 1 4 4 4 2 Apoptosis regulator M11L like Ecm29 PF13001.7 CRK30589.1 - 0.014 14.1 5.2 0.32 9.6 0.1 4.1 3 1 1 5 5 5 0 Proteasome stabiliser Proteasom_PSMB PF10508.9 CRK30589.1 - 0.017 13.7 5.3 0.35 9.3 0.1 2.7 3 1 0 3 3 3 0 Proteasome non-ATPase 26S subunit Arm PF00514.23 CRK30589.1 - 0.029 14.4 2.2 9 6.5 0.0 4.6 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat DUF3301 PF11743.8 CRK30589.1 - 0.11 12.2 0.1 6.1 6.6 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3301) IFRD PF05004.13 CRK30589.1 - 0.69 9.0 4.0 3.7 6.6 0.3 3.5 3 1 1 4 4 4 0 Interferon-related developmental regulator (IFRD) BBP1_C PF15272.6 CRK30590.1 - 0.037 13.9 0.5 0.075 12.9 0.5 1.4 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal ABC_tran_CTD PF16326.5 CRK30590.1 - 0.75 10.1 2.7 7.8 6.8 0.1 2.9 2 2 1 3 3 3 0 ABC transporter C-terminal domain Macin PF14865.6 CRK30592.1 - 0.092 13.3 0.0 0.19 12.3 0.0 1.5 1 0 0 1 1 1 0 Macin Pro-kuma_activ PF09286.11 CRK30593.1 - 9.3e-16 58.4 0.2 1.1e-13 51.7 0.0 2.9 2 1 1 3 3 3 2 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 CRK30593.1 - 3.5e-05 23.2 0.0 7.2e-05 22.2 0.0 1.6 2 0 0 2 2 2 1 Subtilase family ABC_membrane PF00664.23 CRK30594.1 - 1e-88 297.6 26.4 3.7e-45 154.7 9.2 2.6 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CRK30594.1 - 3.4e-27 95.6 0.1 1.5e-16 61.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter MMR_HSR1 PF01926.23 CRK30594.1 - 1.1e-05 25.5 0.4 0.17 12.0 0.3 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CRK30594.1 - 9.1e-05 22.4 0.5 0.23 11.4 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 CRK30594.1 - 0.00067 19.8 0.4 0.11 12.6 0.1 2.5 2 0 0 2 2 2 1 Dynamin family ABC_membrane_2 PF06472.15 CRK30594.1 - 0.0046 16.4 0.1 0.0046 16.4 0.1 2.7 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 AAA_29 PF13555.6 CRK30594.1 - 0.0049 16.6 0.6 2.2 8.1 0.1 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 CRK30594.1 - 0.012 15.4 0.5 5 6.8 0.5 2.3 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CRK30594.1 - 0.018 15.5 0.1 4 7.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain UPF0093 PF03653.13 CRK30594.1 - 0.021 15.1 0.2 0.021 15.1 0.2 2.6 2 0 0 2 2 1 0 Uncharacterised protein family (UPF0093) Zeta_toxin PF06414.12 CRK30594.1 - 0.026 13.8 0.1 1 8.6 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin SMC_N PF02463.19 CRK30594.1 - 0.032 13.7 0.1 3 7.2 0.0 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 CRK30594.1 - 0.043 13.9 3.2 0.58 10.2 0.2 2.7 3 0 0 3 3 2 0 Helicase HerA, central domain AAA_16 PF13191.6 CRK30594.1 - 0.064 13.6 0.1 5.2 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain T2SSE PF00437.20 CRK30594.1 - 0.1 11.6 0.7 0.35 9.9 0.3 2.0 2 1 0 2 2 2 0 Type II/IV secretion system protein AAA_15 PF13175.6 CRK30594.1 - 0.11 12.2 1.0 3.2 7.4 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_27 PF13514.6 CRK30594.1 - 0.12 11.9 0.0 0.58 9.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 CRK30594.1 - 0.18 11.1 0.3 14 4.9 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family GTP_EFTU PF00009.27 CRK30594.1 - 0.19 11.2 0.2 7.3 6.1 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_30 PF13604.6 CRK30594.1 - 0.26 11.0 0.9 3.5 7.3 0.0 2.6 3 0 0 3 3 3 0 AAA domain AIG1 PF04548.16 CRK30594.1 - 0.3 10.4 1.5 4.8 6.4 0.0 2.3 2 0 0 2 2 2 0 AIG1 family Roc PF08477.13 CRK30594.1 - 0.83 9.9 2.6 41 4.4 0.1 3.2 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase MWFE PF15879.5 CRK30594.1 - 1.7 8.9 3.8 2.1 8.6 0.2 3.0 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase MWFE subunit GFA PF04828.14 CRK30596.1 - 2.1e-22 79.3 0.3 3.1e-22 78.7 0.3 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme PIG-H PF10181.9 CRK30599.1 - 3.2e-43 145.5 0.2 2.5e-25 88.1 0.1 2.2 2 0 0 2 2 2 2 GPI-GlcNAc transferase complex, PIG-H component S1FA PF04689.13 CRK30599.1 - 0.27 11.4 2.4 6.8 6.9 0.2 2.5 2 0 0 2 2 2 0 DNA binding protein S1FA V_ATPase_I PF01496.19 CRK30601.1 - 1.5e-151 506.1 1.6 1.8e-151 505.8 1.6 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF2096 PF09869.9 CRK30601.1 - 0.12 12.5 0.8 0.22 11.6 0.6 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2096) C1_1 PF00130.22 CRK30602.1 - 7.2e-21 73.8 31.8 1.4e-12 47.3 11.3 2.2 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C2 PF00168.30 CRK30602.1 - 3.7e-05 24.0 0.0 8.6e-05 22.8 0.0 1.6 2 0 0 2 2 2 1 C2 domain zf-RING_9 PF13901.6 CRK30602.1 - 0.13 12.2 23.9 0.16 11.9 8.1 2.3 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon PHD PF00628.29 CRK30602.1 - 1.7 8.6 27.5 0.069 13.0 8.1 2.6 2 1 0 2 2 2 0 PHD-finger UPF0547 PF10571.9 CRK30602.1 - 5 7.3 12.3 7.9 6.7 1.4 3.7 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 Pkinase PF00069.25 CRK30603.1 - 8.6e-38 130.2 0.0 1.1e-37 129.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK30603.1 - 3.5e-15 56.0 0.0 4.6e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase IBN_N PF03810.19 CRK30604.1 - 1.9e-05 24.5 4.5 2.4e-05 24.1 0.7 2.8 3 0 0 3 3 3 1 Importin-beta N-terminal domain HEAT PF02985.22 CRK30604.1 - 1.9e-05 24.5 0.3 1.4 9.4 0.0 4.3 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 CRK30604.1 - 4.7e-05 23.7 10.2 0.54 10.7 0.1 5.1 3 2 1 5 5 5 3 HEAT repeats CLASP_N PF12348.8 CRK30604.1 - 0.0019 17.8 0.3 0.0076 15.8 0.0 2.0 1 1 0 2 2 2 1 CLASP N terminal HEAT_EZ PF13513.6 CRK30604.1 - 0.0061 17.0 1.0 6.8 7.3 0.0 3.8 3 0 0 3 3 3 1 HEAT-like repeat Adaptin_N PF01602.20 CRK30604.1 - 0.0079 14.8 0.1 1.6 7.2 0.1 2.6 1 1 1 3 3 3 2 Adaptin N terminal region RIX1 PF08167.12 CRK30604.1 - 0.029 14.1 0.1 0.12 12.1 0.0 2.0 1 1 1 2 2 2 0 rRNA processing/ribosome biogenesis DUF3385 PF11865.8 CRK30604.1 - 0.1 12.5 0.1 2.6 7.9 0.1 2.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3385) HAT PF02184.16 CRK30608.1 - 4e-18 65.1 8.2 1.4e-14 53.7 3.4 8.2 9 0 0 9 9 9 3 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 CRK30608.1 - 1.3e-17 63.0 8.2 0.00016 22.2 0.1 6.9 5 2 2 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 CRK30608.1 - 8.1e-11 42.3 0.0 1.6e-06 28.5 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat Suf PF05843.14 CRK30608.1 - 7.2e-10 39.3 5.8 4.3e-05 23.7 0.0 3.9 1 1 2 3 3 3 2 Suppressor of forked protein (Suf) TPR_6 PF13174.6 CRK30608.1 - 1.4e-06 28.5 1.0 0.46 11.2 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 CRK30608.1 - 3.3e-06 27.6 2.7 5.3 7.8 0.0 5.3 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_15 PF13429.6 CRK30608.1 - 7.6e-06 25.3 8.0 0.021 14.0 0.8 3.9 2 1 2 4 4 4 3 Tetratricopeptide repeat U3_assoc_6 PF08640.11 CRK30608.1 - 7e-05 22.8 16.3 0.0031 17.6 0.7 5.0 2 2 1 4 4 4 2 U3 small nucleolar RNA-associated protein 6 TPR_2 PF07719.17 CRK30608.1 - 8.4e-05 22.4 3.3 0.83 9.9 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CRK30608.1 - 0.00015 21.8 1.3 2.8 8.1 0.5 3.9 3 1 1 4 4 4 2 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.6 CRK30608.1 - 0.00021 21.4 0.2 1.9 9.0 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 CRK30608.1 - 0.0023 18.1 1.7 0.11 12.7 0.4 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat NRDE-2 PF08424.10 CRK30608.1 - 0.0035 16.5 9.5 0.21 10.7 2.7 3.6 2 1 1 3 3 2 2 NRDE-2, necessary for RNA interference c-SKI_SMAD_bind PF08782.10 CRK30608.1 - 3.9 7.8 6.4 2 8.7 0.3 3.1 2 2 1 3 3 3 0 c-SKI Smad4 binding domain TPR_10 PF13374.6 CRK30608.1 - 4.3 7.3 11.0 24 5.0 0.2 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Peptidase_M28 PF04389.17 CRK30610.1 - 1.5e-10 41.1 0.0 1.8e-10 40.9 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M28 PF04389.17 CRK30611.1 - 2.4e-24 86.1 0.6 3.1e-21 76.0 0.0 2.3 1 1 1 2 2 2 2 Peptidase family M28 PA PF02225.22 CRK30611.1 - 1.1e-10 41.3 0.1 2e-10 40.5 0.1 1.4 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 CRK30611.1 - 0.042 13.5 0.0 0.079 12.6 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 MUG113 PF13455.6 CRK30614.1 - 3e-45 152.8 0.6 2e-22 79.7 0.2 2.7 2 0 0 2 2 2 2 Meiotically up-regulated gene 113 T5orf172 PF10544.9 CRK30614.1 - 5.7e-44 148.9 0.2 2e-22 79.7 0.2 2.8 2 0 0 2 2 2 2 T5orf172 domain Aa_trans PF01490.18 CRK30614.1 - 5.9e-26 91.1 32.0 7.5e-26 90.8 32.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein GST_N_2 PF13409.6 CRK30614.1 - 7.3e-08 32.6 0.0 3.3e-07 30.5 0.1 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 CRK30614.1 - 1.9e-07 31.4 0.0 5.6e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CRK30614.1 - 2.2e-05 24.4 0.1 5.9e-05 23.0 0.1 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CRK30614.1 - 0.0031 17.7 0.0 0.0071 16.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CRK30614.1 - 0.02 15.1 0.0 0.041 14.1 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain FeoC PF09012.10 CRK30614.1 - 0.17 11.9 0.0 33 4.6 0.0 2.5 2 0 0 2 2 2 0 FeoC like transcriptional regulator Amino_oxidase PF01593.24 CRK30616.1 - 2.3e-54 185.4 0.2 3.9e-54 184.6 0.2 1.3 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CRK30616.1 - 1.9e-13 50.4 0.1 2e-12 47.1 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CRK30616.1 - 9e-08 31.6 0.1 1.5e-07 30.9 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 CRK30616.1 - 1.3e-07 31.4 0.2 2.3e-07 30.5 0.1 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 CRK30616.1 - 4.4e-07 29.8 1.9 8.4e-07 28.9 1.9 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CRK30616.1 - 5.7e-06 25.8 0.0 2.1e-05 23.9 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CRK30616.1 - 8.4e-06 25.2 0.0 2e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 CRK30616.1 - 2.8e-05 23.0 0.1 0.00034 19.4 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 CRK30616.1 - 9.4e-05 21.7 1.3 0.0005 19.3 0.1 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 CRK30616.1 - 0.00028 20.3 0.2 0.00059 19.2 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 CRK30616.1 - 0.00058 19.2 1.1 0.019 14.3 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CRK30616.1 - 0.019 15.5 0.0 0.049 14.2 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CRK30616.1 - 0.025 14.5 3.0 4.3 7.3 0.0 3.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 CRK30616.1 - 0.043 12.9 0.2 0.7 8.9 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein BCS1_N PF08740.11 CRK30617.1 - 4.7e-38 131.0 0.2 7.1e-38 130.5 0.2 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 CRK30617.1 - 3.4e-23 82.5 0.0 6.1e-23 81.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CRK30617.1 - 2.7e-05 24.0 0.0 5.7e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 CRK30617.1 - 0.0013 19.3 0.0 0.0023 18.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 CRK30617.1 - 0.011 15.0 0.0 0.02 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 CRK30617.1 - 0.011 16.1 0.0 0.03 14.7 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.14 CRK30617.1 - 0.023 14.7 0.0 0.089 12.8 0.0 2.1 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CRK30617.1 - 0.055 13.8 0.1 0.18 12.2 0.0 1.8 1 1 1 2 2 2 0 AAA ATPase domain IstB_IS21 PF01695.17 CRK30617.1 - 0.16 11.7 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Amino_oxidase PF01593.24 CRK30618.1 - 2e-45 155.9 0.1 3.9e-45 155.0 0.1 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CRK30618.1 - 0.009 16.2 0.0 0.096 12.9 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain BCS1_N PF08740.11 CRK30619.1 - 1.1e-36 126.6 0.3 1.7e-36 125.9 0.3 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 CRK30619.1 - 5.1e-23 82.0 0.0 8.8e-23 81.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CRK30619.1 - 3e-05 23.8 0.0 5.9e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 CRK30619.1 - 0.001 19.6 0.0 0.002 18.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 CRK30619.1 - 0.0095 16.3 0.0 0.037 14.4 0.0 2.1 2 0 0 2 2 2 1 RNA helicase DUF815 PF05673.13 CRK30619.1 - 0.011 14.9 0.0 0.02 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_5 PF07728.14 CRK30619.1 - 0.029 14.4 0.0 0.11 12.5 0.0 2.0 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CRK30619.1 - 0.05 14.0 0.1 0.19 12.1 0.0 1.9 1 1 0 2 2 2 0 AAA ATPase domain IstB_IS21 PF01695.17 CRK30619.1 - 0.17 11.6 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein SH3BGR PF04908.15 CRK30622.1 - 0.017 15.2 0.1 0.073 13.2 0.0 2.2 2 0 0 2 2 2 0 SH3-binding, glutamic acid-rich protein SOG2 PF10428.9 CRK30622.1 - 0.031 13.5 20.4 0.038 13.2 20.4 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein TRAP_alpha PF03896.16 CRK30622.1 - 2.5 7.2 5.4 3.6 6.7 5.4 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF572 PF04502.13 CRK30622.1 - 8.2 6.0 17.6 12 5.4 17.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) SAPS PF04499.15 CRK30622.1 - 9.5 4.9 9.4 11 4.6 9.4 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PI3_PI4_kinase PF00454.27 CRK30623.1 - 1.3e-08 34.9 0.1 2.4e-08 34.1 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase AAA_32 PF13654.6 CRK30623.1 - 0.0024 16.7 0.0 0.0033 16.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain EF-hand_4 PF12763.7 CRK30624.1 - 2.1e-16 59.8 0.0 1.6e-10 40.8 0.0 2.4 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 CRK30624.1 - 1e-06 29.1 0.0 0.97 9.9 0.0 4.0 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 CRK30624.1 - 1.7e-06 27.5 0.2 1 9.5 0.1 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 CRK30624.1 - 8.1e-06 25.0 0.0 2.5 7.8 0.1 4.2 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 CRK30624.1 - 0.023 14.5 0.0 8.1 6.4 0.0 3.2 3 0 0 3 3 3 0 EF-hand domain pair DUF3243 PF11588.8 CRK30624.1 - 0.19 12.1 0.0 6.3 7.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3243) SNRNP27 PF08648.12 CRK30626.1 - 0.00012 22.1 0.8 0.00033 20.6 0.8 1.8 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins BRF1 PF07741.13 CRK30626.1 - 0.22 11.9 11.5 0.28 11.6 11.5 1.2 1 0 0 1 1 1 0 Brf1-like TBP-binding domain FemAB PF02388.16 CRK30626.1 - 0.57 9.0 4.9 0.66 8.8 4.9 1.0 1 0 0 1 1 1 0 FemAB family Ferlin_C PF16165.5 CRK30626.1 - 1.8 8.5 4.7 2.2 8.2 4.7 1.2 1 0 0 1 1 1 0 Ferlin C-terminus Peptidase_M16 PF00675.20 CRK30631.1 - 1.2e-53 181.1 0.5 8.9e-52 175.0 0.3 2.3 2 0 0 2 2 2 2 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CRK30631.1 - 1.5e-24 87.0 0.3 4.6e-24 85.4 0.1 1.8 2 0 0 2 2 2 1 Peptidase M16 inactive domain M16C_assoc PF08367.11 CRK30631.1 - 0.055 12.6 0.3 0.11 11.6 0.3 1.5 1 1 0 1 1 1 0 Peptidase M16C associated RbsD_FucU PF05025.13 CRK30631.1 - 0.081 13.4 0.2 0.23 11.9 0.0 1.9 2 0 0 2 2 2 0 RbsD / FucU transport protein family LsmAD PF06741.13 CRK30639.1 - 1.6e-28 99.0 1.8 1.6e-28 99.0 1.8 2.4 2 0 0 2 2 2 1 LsmAD domain Peptidase_M16 PF00675.20 CRK30641.1 - 3.4e-21 75.8 0.1 7e-21 74.8 0.1 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CRK30641.1 - 7.4e-11 42.4 0.0 1.3e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain Caps_synth_GfcC PF06251.11 CRK30641.1 - 0.033 13.8 0.0 9.1 5.8 0.0 2.3 2 0 0 2 2 2 0 Capsule biosynthesis GfcC BMC PF00936.19 CRK30641.1 - 0.038 14.0 0.2 0.1 12.6 0.2 1.7 1 0 0 1 1 1 0 BMC domain RNA_pol_Rpc82 PF05645.13 CRK30643.1 - 3.6e-51 174.4 0.0 2.7e-47 161.7 0.0 3.5 3 1 1 4 4 4 2 RNA polymerase III subunit RPC82 HTH_9 PF08221.11 CRK30643.1 - 7.8e-18 64.3 0.2 1.2e-15 57.4 0.0 3.7 4 0 0 4 4 4 1 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 CRK30643.1 - 4e-06 26.6 0.0 0.21 11.4 0.0 3.3 3 1 0 3 3 3 2 TFIIE alpha subunit SNF PF00209.18 CRK30645.1 - 7.3e-80 269.1 26.7 5.6e-78 262.9 26.6 2.2 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family DUF2518 PF10726.9 CRK30645.1 - 0.17 11.5 1.3 0.88 9.2 1.3 2.3 1 0 0 1 1 1 0 Protein of function (DUF2518) Sec6 PF06046.13 CRK30647.1 - 3.5e-185 616.7 12.7 1.8e-166 554.9 8.5 2.3 2 0 0 2 2 2 2 Exocyst complex component Sec6 Vps53_N PF04100.12 CRK30647.1 - 2.2e-05 23.6 0.6 2.2e-05 23.6 0.6 2.2 3 0 0 3 3 3 1 Vps53-like, N-terminal OmdA PF13376.6 CRK30647.1 - 0.0048 16.9 4.5 0.32 11.0 0.0 4.4 4 0 0 4 4 4 1 Bacteriocin-protection, YdeI or OmpD-Associated DUF1294 PF06961.13 CRK30647.1 - 0.019 15.2 0.0 13 6.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1294) DUF755 PF05501.11 CRK30647.1 - 0.064 13.5 0.1 0.13 12.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Syntaxin_2 PF14523.6 CRK30647.1 - 0.67 10.4 2.6 14 6.1 0.3 2.9 2 0 0 2 2 2 0 Syntaxin-like protein DASH_Duo1 PF08651.10 CRK30647.1 - 0.85 9.4 3.0 2.1 8.2 0.4 3.1 2 1 1 3 3 3 0 DASH complex subunit Duo1 Pirin PF02678.16 CRK30649.1 - 2.2e-30 104.8 0.0 4.2e-30 103.9 0.0 1.5 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 CRK30649.1 - 5.6e-29 100.6 0.0 3.5e-27 94.8 0.0 2.2 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 CRK30649.1 - 1.2e-08 34.5 0.6 3.2e-05 23.5 0.4 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 CRK30649.1 - 0.0038 16.9 0.0 0.22 11.2 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF861) Perilipin PF03036.16 CRK30650.1 - 0.1 11.6 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Perilipin family Glyco_hydro_115 PF15979.5 CRK30652.1 - 3.4e-79 266.7 0.1 5.5e-79 266.1 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 115 Fungal_trans PF04082.18 CRK30653.1 - 3.2e-07 29.7 0.8 6.3e-07 28.7 0.8 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK30653.1 - 1.2e-06 28.5 10.7 1.9e-06 27.9 10.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cutinase PF01083.22 CRK30654.1 - 5.2e-10 39.6 0.0 8.6e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Cutinase Phage_prot_Gp6 PF05133.14 CRK30655.1 - 0.078 12.1 0.1 0.1 11.7 0.1 1.1 1 0 0 1 1 1 0 Phage portal protein, SPP1 Gp6-like Oxysterol_BP PF01237.18 CRK30656.1 - 1.8e-108 362.7 0.1 2e-108 362.5 0.1 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein TPX2 PF06886.11 CRK30656.1 - 0.34 11.2 5.0 0.55 10.5 5.0 1.3 1 0 0 1 1 1 0 Targeting protein for Xklp2 (TPX2) ADH_N PF08240.12 CRK30659.1 - 1.7e-18 66.5 0.3 3.2e-18 65.6 0.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CRK30659.1 - 1.1e-16 61.0 0.0 1.6e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 CRK30659.1 - 1.1e-05 25.1 0.5 0.0017 17.9 0.2 2.4 2 1 0 2 2 2 2 Glucose dehydrogenase C-terminus HTH_32 PF13565.6 CRK30661.1 - 2.7 8.7 5.9 2 9.1 2.9 2.4 2 1 0 2 2 2 0 Homeodomain-like domain Clr5 PF14420.6 CRK30662.1 - 7.2e-17 61.4 1.1 4.9e-16 58.7 1.6 2.0 2 0 0 2 2 2 1 Clr5 domain Arrestin_C PF02752.22 CRK30663.1 - 2.3e-16 60.5 0.0 4.2e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Zn_clus PF00172.18 CRK30664.1 - 4.4e-07 29.9 11.4 4.4e-07 29.9 11.4 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Prefoldin_2 PF01920.20 CRK30664.1 - 0.052 13.5 0.6 0.083 12.9 0.6 1.2 1 0 0 1 1 1 0 Prefoldin subunit Glyco_hydro_32N PF00251.20 CRK30666.1 - 1.2e-50 172.8 0.0 2.7e-37 129.0 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 CRK30666.1 - 1.3e-25 90.2 0.0 2e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal BNR_2 PF13088.6 CRK30666.1 - 0.12 11.7 1.3 0.78 9.0 1.3 2.1 1 1 0 1 1 1 0 BNR repeat-like domain BNR PF02012.20 CRK30666.1 - 0.25 11.5 0.2 0.25 11.5 0.2 4.2 4 0 0 4 4 4 0 BNR/Asp-box repeat Sugar_tr PF00083.24 CRK30667.1 - 1e-79 268.5 19.4 1.2e-79 268.3 19.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK30667.1 - 4.1e-21 75.3 24.6 4.1e-21 75.3 24.6 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 CRK30667.1 - 0.00013 20.7 18.9 0.0057 15.3 2.2 2.6 2 1 0 2 2 2 2 MFS/sugar transport protein WD40 PF00400.32 CRK30668.1 - 9.5e-13 48.4 12.9 0.00083 20.1 0.5 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK30668.1 - 1.3e-08 35.0 0.1 0.0072 16.6 0.0 3.4 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CRK30668.1 - 0.0028 17.6 0.0 0.014 15.3 0.0 1.9 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 CRK30668.1 - 0.0086 14.6 0.0 0.015 13.9 0.0 1.3 1 0 0 1 1 1 1 Cytochrome D1 heme domain PD40 PF07676.12 CRK30668.1 - 0.028 14.4 0.0 4.9 7.2 0.0 2.7 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat VID27 PF08553.10 CRK30668.1 - 0.12 11.4 0.0 0.18 10.8 0.0 1.1 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain EF_assoc_2 PF08356.12 CRK30670.1 - 6.8e-36 122.1 0.0 1.3e-35 121.3 0.0 1.5 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.12 CRK30670.1 - 6.8e-30 102.5 1.5 1.4e-29 101.5 1.5 1.5 1 0 0 1 1 1 1 EF hand associated Ras PF00071.22 CRK30670.1 - 1.7e-19 70.0 0.0 3.6e-13 49.4 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 CRK30670.1 - 2.3e-12 47.2 0.0 3.3e-08 33.8 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase EF-hand_1 PF00036.32 CRK30670.1 - 4.5e-07 29.0 5.3 0.0054 16.2 1.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CRK30670.1 - 8.9e-07 29.3 1.6 0.0015 18.9 0.2 2.5 2 0 0 2 2 2 2 EF-hand domain pair MMR_HSR1 PF01926.23 CRK30670.1 - 1.1e-06 28.6 0.0 0.026 14.6 0.0 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.23 CRK30670.1 - 1.6e-06 28.3 0.1 0.062 13.4 0.0 3.5 3 1 1 4 4 4 2 Dynamin family EF-hand_6 PF13405.6 CRK30670.1 - 5.2e-06 26.0 5.5 0.0054 16.6 0.4 2.6 2 0 0 2 2 2 2 EF-hand domain AAA_16 PF13191.6 CRK30670.1 - 9.5e-05 22.8 0.0 0.18 12.2 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain EF-hand_5 PF13202.6 CRK30670.1 - 0.00038 19.8 8.3 0.023 14.2 3.2 2.7 2 0 0 2 2 2 2 EF hand AAA_29 PF13555.6 CRK30670.1 - 0.00046 19.9 0.0 0.46 10.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_28 PF13521.6 CRK30670.1 - 0.001 19.3 0.0 1.6 9.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 CRK30670.1 - 0.007 16.6 0.0 0.5 10.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 CRK30670.1 - 0.0096 15.8 0.0 1.2 9.0 0.0 3.1 2 1 0 3 3 3 1 RsgA GTPase AAA_24 PF13479.6 CRK30670.1 - 0.011 15.5 0.0 0.14 11.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.27 CRK30670.1 - 0.011 15.3 0.0 5 6.6 0.0 3.2 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain Ploopntkinase3 PF18751.1 CRK30670.1 - 0.022 14.6 0.0 3.7 7.4 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 RNA_helicase PF00910.22 CRK30670.1 - 0.023 15.1 0.0 0.42 11.0 0.0 2.4 2 0 0 2 2 2 0 RNA helicase ABC_tran PF00005.27 CRK30670.1 - 0.025 15.1 0.0 2.1 8.8 0.0 2.5 2 0 0 2 2 2 0 ABC transporter Septin PF00735.18 CRK30670.1 - 0.12 11.6 0.0 0.28 10.4 0.0 1.5 2 0 0 2 2 2 0 Septin DUF815 PF05673.13 CRK30670.1 - 0.15 11.2 0.0 1.2 8.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) EF-hand_10 PF14788.6 CRK30670.1 - 0.16 11.8 2.8 0.41 10.6 0.2 2.3 2 0 0 2 2 2 0 EF hand AAA_18 PF13238.6 CRK30670.1 - 0.17 12.4 0.0 1.6 9.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain EF-hand_8 PF13833.6 CRK30670.1 - 6 6.8 6.5 4.7 7.1 1.3 2.4 2 0 0 2 2 2 0 EF-hand domain pair Meth_synt_2 PF01717.18 CRK30674.1 - 2.5e-112 375.3 0.0 2.8e-112 375.2 0.0 1.0 1 0 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 CRK30674.1 - 3.3e-05 23.5 0.0 0.00015 21.4 0.0 1.8 1 1 1 2 2 2 1 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.17 CRK30674.1 - 0.0017 17.6 0.0 0.0026 17.0 0.0 1.3 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) DUF3018 PF11455.8 CRK30674.1 - 0.1 12.5 0.0 0.33 10.9 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3018) Aminotran_1_2 PF00155.21 CRK30676.1 - 5.3e-61 206.8 0.0 6e-61 206.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 CRK30676.1 - 0.0023 16.9 0.0 0.0044 16.0 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V Cu_amine_oxidN3 PF02728.16 CRK30677.1 - 6.8e-20 71.4 0.0 1.8e-19 70.0 0.0 1.8 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxid PF01179.20 CRK30677.1 - 2.3e-12 46.6 0.1 3e-12 46.2 0.1 1.2 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 CRK30677.1 - 6.2e-12 45.6 0.1 9.7e-12 45.0 0.1 1.3 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Peptidase_C14 PF00656.22 CRK30678.1 - 3.8e-50 171.1 0.0 4.6e-50 170.9 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 CRK30678.1 - 0.12 12.3 0.0 0.38 10.7 0.0 1.8 2 0 0 2 2 2 0 Raptor N-terminal CASPase like domain DEAD PF00270.29 CRK30680.1 - 4.8e-44 150.2 0.1 7e-44 149.7 0.1 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CRK30680.1 - 2.8e-06 27.4 0.4 5.7e-06 26.4 0.2 1.7 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 CRK30680.1 - 0.0012 18.3 4.2 0.44 9.9 1.8 2.4 3 0 0 3 3 3 2 U3-containing 90S pre-ribosomal complex subunit CCDC117 PF15810.5 CRK30680.1 - 0.048 14.0 4.6 0.26 11.6 0.0 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 117 DUF2325 PF10087.9 CRK30680.1 - 0.28 11.3 1.8 0.34 11.1 0.0 2.0 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2325) PGBA_C PF15437.6 CRK30680.1 - 1.8 9.0 17.1 0.26 11.7 11.6 2.2 2 0 0 2 2 2 0 Plasminogen-binding protein pgbA C-terminal Ecm29 PF13001.7 CRK30681.1 - 4.8e-68 230.0 0.1 4.3e-66 223.6 0.0 3.4 3 1 0 3 3 3 1 Proteasome stabiliser HEAT_2 PF13646.6 CRK30681.1 - 2.4e-05 24.6 9.1 0.066 13.6 0.1 6.1 6 1 0 6 6 6 1 HEAT repeats HEAT_EZ PF13513.6 CRK30681.1 - 0.0019 18.7 1.5 67 4.1 0.2 6.4 5 1 0 5 5 5 0 HEAT-like repeat MMS19_C PF12460.8 CRK30681.1 - 0.0031 16.7 0.1 4.4 6.3 0.0 4.4 7 0 0 7 7 7 1 RNAPII transcription regulator C-terminal DUF3385 PF11865.8 CRK30681.1 - 0.0034 17.3 0.1 6.2 6.7 0.0 3.7 4 0 0 4 4 4 1 Domain of unknown function (DUF3385) CLASP_N PF12348.8 CRK30681.1 - 0.013 15.0 0.6 3.1 7.3 0.0 3.4 3 1 1 4 4 4 0 CLASP N terminal Vac14_Fab1_bd PF12755.7 CRK30681.1 - 0.11 13.1 0.1 2.8 8.6 0.0 3.5 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region HEAT PF02985.22 CRK30681.1 - 0.22 11.9 8.4 97 3.7 0.0 7.0 8 0 0 8 8 8 0 HEAT repeat SBD_N PF07005.11 CRK30682.1 - 1.2e-56 192.0 2.0 1.2e-56 192.0 2.0 1.7 2 0 0 2 2 2 1 Sugar-binding N-terminal domain NBD_C PF17042.5 CRK30682.1 - 1e-24 87.9 1.8 1e-24 87.9 1.8 2.2 3 0 0 3 3 3 1 Nucleotide-binding C-terminal domain Iso_dh PF00180.20 CRK30683.1 - 7.4e-20 71.4 0.1 1.3e-15 57.5 0.0 2.1 2 0 0 2 2 2 2 Isocitrate/isopropylmalate dehydrogenase HHH_2 PF12826.7 CRK30683.1 - 0.19 11.8 0.3 0.64 10.2 0.0 2.0 3 0 0 3 3 3 0 Helix-hairpin-helix motif Fungal_trans_2 PF11951.8 CRK30684.1 - 4.7e-11 42.1 0.7 8.8e-08 31.3 0.2 2.5 3 0 0 3 3 3 2 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK30684.1 - 8.1e-08 32.3 19.4 5.9e-06 26.3 6.6 2.6 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain MutS_V PF00488.21 CRK30687.1 - 3.2e-84 281.7 0.7 4e-84 281.3 0.7 1.1 1 0 0 1 1 1 1 MutS domain V AAA_27 PF13514.6 CRK30687.1 - 0.017 14.7 0.0 0.037 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CRK30687.1 - 0.14 12.5 0.1 0.75 10.1 0.0 2.1 2 1 0 2 2 2 0 AAA domain DUF1682 PF07946.14 CRK30689.1 - 1.2e-71 241.6 0.0 1.4e-71 241.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Big_3 PF07523.12 CRK30689.1 - 0.041 14.2 0.0 11 6.3 0.0 2.7 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) SKIP_SNW PF02731.15 CRK30690.1 - 3.2e-55 186.2 1.0 4.5e-55 185.7 1.0 1.2 1 0 0 1 1 1 1 SKIP/SNW domain Tho2 PF11262.8 CRK30691.1 - 2e-54 184.8 0.1 2.2e-54 184.7 0.1 1.0 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 OTT_1508_deam PF14441.6 CRK30693.1 - 2.8e-20 72.1 0.1 3.9e-19 68.4 0.1 2.3 2 0 0 2 2 2 1 OTT_1508-like deaminase FA_desaturase PF00487.24 CRK30694.1 - 6.9e-31 108.0 21.3 1.1e-30 107.4 21.3 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 CRK30694.1 - 4.1e-09 36.5 0.0 8.7e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain p450 PF00067.22 CRK30695.1 - 8.5e-64 216.0 0.0 1.1e-63 215.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Arylsulfotran_2 PF14269.6 CRK30697.1 - 1.1e-47 162.9 0.0 4.1e-47 161.0 0.0 1.8 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 CRK30697.1 - 1.1e-08 34.4 0.0 4.3e-07 29.2 0.0 2.1 2 0 0 2 2 2 2 Arylsulfotransferase (ASST) MFS_1 PF07690.16 CRK30697.1 - 0.12 11.2 13.5 0.023 13.6 9.0 1.8 1 1 1 2 2 2 0 Major Facilitator Superfamily Ferritin_2 PF13668.6 CRK30699.1 - 0.0016 18.7 0.0 0.0027 17.9 0.0 1.3 1 0 0 1 1 1 1 Ferritin-like domain AflR PF08493.10 CRK30699.1 - 1.3 8.4 6.4 2.1 7.8 6.4 1.2 1 0 0 1 1 1 0 Aflatoxin regulatory protein FKBP_C PF00254.28 CRK30700.1 - 2.6e-32 111.0 0.1 8.5e-32 109.4 0.0 1.8 1 1 1 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase HALZ PF02183.18 CRK30702.1 - 0.00015 21.9 16.1 0.05 13.8 0.2 5.0 4 1 1 5 5 5 2 Homeobox associated leucine zipper TPR_MLP1_2 PF07926.12 CRK30702.1 - 0.0058 16.7 19.7 0.025 14.6 0.9 3.1 2 1 1 3 3 3 2 TPR/MLP1/MLP2-like protein DUF4201 PF13870.6 CRK30702.1 - 0.0079 15.9 20.3 0.32 10.7 1.8 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4201) Serine_rich PF08824.10 CRK30702.1 - 0.0093 16.0 2.9 0.0093 16.0 2.9 2.4 2 1 0 2 2 2 1 Serine rich protein interaction domain CorA PF01544.18 CRK30702.1 - 0.013 14.8 1.7 0.013 14.8 1.7 2.2 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein HIP1_clath_bdg PF16515.5 CRK30702.1 - 0.073 13.7 25.0 0.077 13.6 2.2 3.0 2 1 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Fez1 PF06818.15 CRK30702.1 - 0.13 12.7 25.9 0.82 10.1 13.3 2.1 1 1 1 2 2 2 0 Fez1 CENP-H PF05837.12 CRK30702.1 - 0.2 12.1 21.9 0.22 11.9 7.6 3.0 2 2 1 3 3 3 0 Centromere protein H (CENP-H) HlyD_2 PF12700.7 CRK30702.1 - 0.29 9.8 7.2 0.056 12.2 2.3 1.9 2 0 0 2 2 2 0 HlyD family secretion protein TSC22 PF01166.18 CRK30702.1 - 0.37 11.1 11.4 1.5 9.2 0.5 3.9 4 0 0 4 4 4 0 TSC-22/dip/bun family COG2 PF06148.11 CRK30702.1 - 0.41 10.7 13.0 0.14 12.2 1.3 3.2 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 YabA PF06156.13 CRK30702.1 - 0.47 11.1 18.4 1.2 9.8 2.3 3.7 2 2 1 3 3 3 0 Initiation control protein YabA CENP-F_leu_zip PF10473.9 CRK30702.1 - 0.63 10.1 23.7 3.8 7.5 10.9 3.6 2 2 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Mt_ATP-synt_B PF05405.14 CRK30702.1 - 0.88 9.2 12.6 3.2 7.4 1.3 2.3 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF4140 PF13600.6 CRK30702.1 - 1.7 9.1 20.6 1.5 9.3 1.7 3.8 2 2 2 4 4 4 0 N-terminal domain of unknown function (DUF4140) DivIC PF04977.15 CRK30702.1 - 3 7.7 21.3 4.7 7.0 0.2 4.7 2 2 2 4 4 4 0 Septum formation initiator Spc7 PF08317.11 CRK30702.1 - 3.4 6.5 23.0 2.3 7.0 5.6 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein ABC_tran_CTD PF16326.5 CRK30702.1 - 4.4 7.6 17.4 0.8 10.0 0.4 4.2 2 2 2 4 4 4 0 ABC transporter C-terminal domain DUF3810 PF12725.7 CRK30702.1 - 4.4 6.6 9.1 0.7 9.2 2.6 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3810) NYD-SP28_assoc PF14775.6 CRK30702.1 - 4.7 7.4 11.3 15 5.7 0.1 3.6 3 0 0 3 3 3 0 Sperm tail C-terminal domain Fungal_TACC PF12709.7 CRK30702.1 - 4.7 7.7 14.7 0.56 10.7 0.2 3.9 2 2 2 4 4 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins JIP_LZII PF16471.5 CRK30702.1 - 7.5 6.8 20.0 0.4 10.9 0.3 4.6 4 2 1 5 5 4 0 JNK-interacting protein leucine zipper II DUF883 PF05957.13 CRK30702.1 - 8.7 7.0 15.0 5.3 7.7 1.4 3.1 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF883) NPV_P10 PF05531.12 CRK30702.1 - 8.9 6.9 14.4 1 9.9 2.1 3.6 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Syntaxin-6_N PF09177.11 CRK30702.1 - 9.6 6.8 13.2 1.1 9.8 1.8 2.6 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Mcp5_PH PF12814.7 CRK30703.1 - 5.5e-49 165.3 0.0 6.6e-49 165.1 0.0 1.1 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH_12 PF16457.5 CRK30703.1 - 0.0018 18.8 0.1 0.015 15.8 0.1 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain Complex1_30kDa PF00329.19 CRK30704.1 - 9.1e-45 152.2 0.0 1.2e-44 151.8 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit PIP49_N PF14875.6 CRK30704.1 - 0.15 11.9 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 N-term cysteine-rich ER, FAM69 Fib_alpha PF08702.10 CRK30705.1 - 0.0034 17.6 5.3 0.0088 16.2 1.1 2.7 2 1 1 3 3 3 1 Fibrinogen alpha/beta chain family PEP-utilisers_N PF05524.13 CRK30705.1 - 0.027 14.6 7.1 0.51 10.5 3.9 3.0 2 1 2 4 4 4 0 PEP-utilising enzyme, N-terminal AAA_13 PF13166.6 CRK30705.1 - 0.037 12.7 2.1 0.058 12.0 2.1 1.3 1 0 0 1 1 1 0 AAA domain Effector_1 PF04518.12 CRK30705.1 - 0.045 12.8 0.5 0.068 12.3 0.5 1.2 1 0 0 1 1 1 0 Effector from type III secretion system SlyX PF04102.12 CRK30705.1 - 0.13 12.9 12.7 7 7.3 4.2 4.0 2 1 2 4 4 4 0 SlyX C_Hendra PF16821.5 CRK30705.1 - 0.16 11.8 2.2 0.16 11.9 0.8 1.7 1 1 0 1 1 1 0 C protein from hendra and measles viruses TMCO5 PF14992.6 CRK30705.1 - 0.37 10.3 9.9 0.1 12.2 6.9 1.5 2 0 0 2 2 2 0 TMCO5 family Wtap PF17098.5 CRK30705.1 - 1.1 9.2 8.7 8.1 6.4 7.4 2.8 2 1 0 2 2 2 0 WTAP/Mum2p family FlaC_arch PF05377.11 CRK30705.1 - 3.4 8.1 10.5 31 5.0 0.2 4.1 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) SH3_1 PF00018.28 CRK30707.1 - 1.4e-17 63.0 0.3 6e-17 61.0 0.1 2.1 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 CRK30707.1 - 2.3e-14 52.8 0.1 4.3e-14 51.9 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 CRK30707.1 - 1.5e-13 50.3 0.4 1.5e-13 50.3 0.4 1.8 2 0 0 2 2 2 1 Variant SH3 domain WW PF00397.26 CRK30707.1 - 0.01 15.9 0.0 0.028 14.5 0.0 1.7 1 0 0 1 1 1 0 WW domain EF1G PF00647.19 CRK30708.1 - 2.5e-43 146.5 0.0 3.8e-43 145.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain DEC-1_N PF04625.13 CRK30708.1 - 0.012 14.6 5.8 0.016 14.3 5.8 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Ribosomal_L1 PF00687.21 CRK30711.1 - 1.4e-44 152.2 0.1 1.6e-44 152.1 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Ndr PF03096.14 CRK30711.1 - 0.055 12.2 0.0 0.077 11.7 0.0 1.2 1 0 0 1 1 1 0 Ndr family SNF PF00209.18 CRK30711.1 - 0.084 11.6 0.1 0.11 11.1 0.1 1.1 1 0 0 1 1 1 0 Sodium:neurotransmitter symporter family Glyco_transf_22 PF03901.17 CRK30712.1 - 4.9e-46 157.8 11.8 7e-46 157.3 11.8 1.2 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PMT_2 PF13231.6 CRK30712.1 - 0.0044 17.3 5.8 0.01 16.0 5.8 1.6 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Skp1 PF01466.19 CRK30713.1 - 4.8e-29 100.2 0.4 9.1e-29 99.3 0.4 1.5 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 CRK30713.1 - 4.9e-19 68.3 0.0 1.1e-18 67.2 0.0 1.6 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Ribosomal_L39 PF00832.20 CRK30714.1 - 2.4e-23 81.5 9.0 2.8e-23 81.3 9.0 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Arf PF00025.21 CRK30715.1 - 2.3e-73 245.4 0.0 2.6e-73 245.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CRK30715.1 - 1.5e-14 54.3 0.0 2e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CRK30715.1 - 2.2e-12 46.8 0.0 2.6e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 CRK30715.1 - 2.7e-11 43.2 0.3 2.5e-07 30.2 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 CRK30715.1 - 4.2e-11 42.7 0.0 5.1e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 CRK30715.1 - 5.9e-08 32.4 0.0 7.5e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CRK30715.1 - 1.3e-06 28.5 0.0 2.1e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CRK30715.1 - 0.0013 18.3 0.0 0.11 12.0 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 CRK30715.1 - 0.0092 15.5 0.9 0.045 13.3 0.8 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_18 PF13238.6 CRK30715.1 - 0.15 12.6 0.1 0.27 11.8 0.0 1.4 1 1 0 1 1 1 0 AAA domain Catalase PF00199.19 CRK30717.1 - 1.3e-174 580.9 0.0 2.3e-174 580.0 0.0 1.3 1 1 0 1 1 1 1 Catalase Catalase-rel PF06628.12 CRK30717.1 - 0.0035 17.5 0.0 0.011 15.9 0.0 1.8 1 0 0 1 1 1 1 Catalase-related immune-responsive PG_binding_3 PF09374.10 CRK30717.1 - 0.075 13.3 0.0 0.22 11.8 0.0 1.8 1 0 0 1 1 1 0 Predicted Peptidoglycan domain PQ-loop PF04193.14 CRK30718.1 - 4.8e-39 131.9 13.4 8e-20 70.4 1.2 3.3 3 0 0 3 3 3 2 PQ loop repeat MFS_1 PF07690.16 CRK30718.1 - 1.8e-07 30.5 44.5 0.0001 21.3 20.7 4.0 3 1 0 3 3 3 3 Major Facilitator Superfamily MtN3_slv PF03083.16 CRK30718.1 - 1.2 9.3 5.5 1.3 9.1 0.2 3.5 3 0 0 3 3 3 0 Sugar efflux transporter for intercellular exchange NUDIX PF00293.28 CRK30719.1 - 1.1e-16 61.1 0.0 2.1e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 CRK30719.1 - 3.2e-13 50.2 0.0 1.3e-12 48.3 0.0 2.0 2 0 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 CRK30719.1 - 5.3e-07 29.2 3.6 9.1e-07 28.4 3.6 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Reticulon PF02453.17 CRK30720.1 - 4.3e-15 56.0 0.7 6e-15 55.5 0.7 1.2 1 0 0 1 1 1 1 Reticulon Pex24p PF06398.11 CRK30720.1 - 0.038 13.0 0.2 0.057 12.4 0.2 1.3 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin G0-G1_switch_2 PF15103.6 CRK30720.1 - 0.31 11.5 1.9 0.59 10.6 0.0 2.3 3 0 0 3 3 3 0 G0/G1 switch protein 2 YtxH PF12732.7 CRK30720.1 - 0.31 11.6 6.5 28 5.4 6.5 2.5 1 1 0 1 1 1 0 YtxH-like protein Apolipoprotein PF01442.18 CRK30720.1 - 0.95 9.3 9.6 0.029 14.2 3.1 1.7 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain BING4CT PF08149.11 CRK30726.1 - 1.9e-36 123.7 0.0 1.3e-34 117.8 0.0 2.4 2 0 0 2 2 2 1 BING4CT (NUC141) domain WD40 PF00400.32 CRK30726.1 - 0.0076 17.1 0.0 0.44 11.5 0.0 2.8 3 0 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK30726.1 - 0.024 14.9 0.8 9.1 6.7 0.0 3.4 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain CHASE3 PF05227.13 CRK30726.1 - 0.12 12.2 3.6 0.18 11.7 3.6 1.3 1 0 0 1 1 1 0 CHASE3 domain PP2C PF00481.21 CRK30730.1 - 6.5e-06 26.0 1.0 8.5e-06 25.6 0.0 1.6 2 0 0 2 2 2 1 Protein phosphatase 2C Adap_comp_sub PF00928.21 CRK30735.1 - 1.7e-10 40.7 0.0 2.2e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family AAA_16 PF13191.6 CRK30738.1 - 2e-05 25.0 0.2 0.00026 21.4 0.0 2.1 1 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 CRK30738.1 - 8.7e-05 22.5 0.0 0.00015 21.7 0.0 1.4 1 0 0 1 1 1 1 NACHT domain SRP54 PF00448.22 CRK30738.1 - 0.00096 18.8 0.0 0.0014 18.3 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_33 PF13671.6 CRK30738.1 - 0.0013 18.9 0.0 0.0025 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CRK30738.1 - 0.0017 18.9 0.0 0.0032 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 CRK30738.1 - 0.002 17.4 0.0 0.0032 16.8 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin MeaB PF03308.16 CRK30738.1 - 0.0029 16.6 0.0 0.0052 15.8 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB KAP_NTPase PF07693.14 CRK30738.1 - 0.0068 15.7 0.0 0.0068 15.7 0.0 1.1 1 0 0 1 1 1 1 KAP family P-loop domain TsaE PF02367.17 CRK30738.1 - 0.018 15.1 0.0 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 CRK30738.1 - 0.018 15.0 0.0 0.035 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 CRK30738.1 - 0.03 14.8 0.0 0.048 14.1 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ArsA_ATPase PF02374.15 CRK30738.1 - 0.042 13.0 0.0 0.065 12.4 0.0 1.1 1 0 0 1 1 1 0 Anion-transporting ATPase Thymidylate_kin PF02223.17 CRK30738.1 - 0.064 12.9 0.0 0.31 10.7 0.0 1.9 2 0 0 2 2 2 0 Thymidylate kinase AAA_5 PF07728.14 CRK30738.1 - 0.073 13.1 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MobB PF03205.14 CRK30738.1 - 0.076 12.9 0.0 1.3 9.0 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 CRK30738.1 - 0.11 12.3 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 NTPase CbiA PF01656.23 CRK30738.1 - 0.12 12.5 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.6 CRK30738.1 - 0.12 12.6 0.0 0.21 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CRK30738.1 - 0.14 11.8 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 CRK30738.1 - 0.23 10.6 0.0 0.31 10.2 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Kinesin PF00225.23 CRK30741.1 - 9.3e-85 284.5 0.2 1.1e-84 284.2 0.2 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CRK30741.1 - 3.6e-28 98.4 0.0 5.9e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding AAA_33 PF13671.6 CRK30741.1 - 0.013 15.7 0.1 0.024 14.8 0.1 1.6 1 1 0 1 1 1 0 AAA domain DUF1344 PF07076.11 CRK30744.1 - 0.037 14.0 0.1 0.079 12.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1344) Lipase_GDSL_2 PF13472.6 CRK30745.1 - 3.5e-14 53.6 2.9 5.1e-14 53.1 2.9 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 CRK30745.1 - 0.00033 20.7 0.0 0.00047 20.2 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase p450 PF00067.22 CRK30747.1 - 7.8e-19 67.8 0.0 1e-18 67.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 CRK30748.1 - 4.6e-20 71.8 0.0 5.7e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 CRK30750.1 - 1.3e-37 129.6 0.0 1.6e-37 129.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SQHop_cyclase_N PF13249.6 CRK30751.1 - 7.3e-37 127.0 0.8 1.3e-36 126.2 0.8 1.4 1 0 0 1 1 1 1 Squalene-hopene cyclase N-terminal domain HD_3 PF13023.6 CRK30751.1 - 3.8e-33 114.7 0.7 6.4e-33 114.0 0.7 1.3 1 0 0 1 1 1 1 HD domain SQHop_cyclase_C PF13243.6 CRK30751.1 - 6.3e-09 35.4 0.0 2.1e-08 33.6 0.0 1.8 2 0 0 2 2 2 1 Squalene-hopene cyclase C-terminal domain Prenyltrans PF00432.21 CRK30751.1 - 2.7e-06 27.0 0.0 0.0002 21.0 0.0 3.4 3 0 0 3 3 3 1 Prenyltransferase and squalene oxidase repeat HD_2 PF12917.7 CRK30751.1 - 4.9e-05 23.2 0.3 9.4e-05 22.2 0.3 1.4 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 CRK30751.1 - 0.13 12.5 0.2 0.3 11.3 0.2 1.6 1 0 0 1 1 1 0 HD domain KH_1 PF00013.29 CRK30753.1 - 2.1e-32 110.7 0.9 7.9e-15 54.4 0.0 4.0 4 0 0 4 4 4 3 KH domain KH_2 PF07650.17 CRK30753.1 - 0.00046 20.0 3.5 0.39 10.6 0.0 3.0 3 0 0 3 3 3 2 KH domain FAM117 PF15388.6 CRK30753.1 - 0.023 14.1 0.1 0.057 12.8 0.1 1.7 1 1 0 1 1 1 0 Protein Family FAM117 Pkinase PF00069.25 CRK30756.1 - 1.1e-54 185.6 0.1 1.3e-54 185.4 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK30756.1 - 1e-33 116.7 0.0 1.3e-33 116.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CRK30756.1 - 6.9e-07 28.9 0.0 8.3e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CRK30756.1 - 2.4e-05 23.5 0.2 3e-05 23.1 0.2 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CRK30756.1 - 2.5e-05 23.7 0.2 3.2e-05 23.4 0.2 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CRK30756.1 - 6e-05 23.1 0.0 0.0029 17.6 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CRK30756.1 - 0.0002 21.0 0.5 0.00025 20.7 0.5 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 CRK30756.1 - 0.0014 18.3 0.5 0.0019 17.8 0.5 1.1 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 CRK30756.1 - 0.037 12.8 0.0 0.056 12.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase PUF PF00806.19 CRK30759.1 - 5.8e-24 82.4 0.0 0.0007 19.1 0.0 5.2 5 0 0 5 5 5 4 Pumilio-family RNA binding repeat Adap_comp_sub PF00928.21 CRK30760.1 - 2.7e-85 285.9 0.0 3.1e-85 285.8 0.0 1.0 1 0 0 1 1 1 1 Adaptor complexes medium subunit family RIBIOP_C PF04950.12 CRK30760.1 - 0.056 12.9 0.0 0.092 12.2 0.0 1.3 1 0 0 1 1 1 0 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal muHD PF10291.9 CRK30760.1 - 0.14 11.5 0.4 0.25 10.7 0.1 1.6 2 0 0 2 2 2 0 Muniscin C-terminal mu homology domain Glyco_hydro_6 PF01341.17 CRK30761.1 - 6.6e-73 246.1 1.1 8.3e-73 245.8 1.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 NMT1 PF09084.11 CRK30762.1 - 9.1e-80 267.6 0.0 1.2e-79 267.3 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 CRK30762.1 - 4.3e-06 26.6 0.3 0.21 11.2 0.0 3.3 3 1 0 3 3 3 2 NMT1-like family Phosphonate-bd PF12974.7 CRK30762.1 - 0.037 13.6 0.0 0.061 12.9 0.0 1.3 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein PBP_like PF12727.7 CRK30762.1 - 0.091 11.9 0.0 0.45 9.6 0.0 1.9 1 1 1 2 2 2 0 PBP superfamily domain TFIIS_M PF07500.14 CRK30764.1 - 3.2e-27 95.2 0.7 6.7e-27 94.2 0.7 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 CRK30764.1 - 3.1e-14 52.5 4.4 5.3e-14 51.8 4.4 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 CRK30764.1 - 1.1e-06 28.6 0.8 2.2e-06 27.6 0.5 1.8 2 0 0 2 2 2 1 TFIIS helical bundle-like domain zf-ZPR1 PF03367.13 CRK30764.1 - 0.015 15.2 0.6 0.24 11.2 0.1 2.3 1 1 1 2 2 2 0 ZPR1 zinc-finger domain DFRP_C PF16543.5 CRK30764.1 - 0.073 13.6 3.0 0.82 10.2 0.1 2.3 2 0 0 2 2 2 0 DRG Family Regulatory Proteins, Tma46 HA2 PF04408.23 CRK30765.1 - 5.8e-18 65.1 0.0 1.2e-17 64.2 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CRK30765.1 - 3.2e-06 27.5 0.0 5.5e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RNA_pol_Rpb1_4 PF05000.17 CRK30766.1 - 3.4e-38 129.9 0.1 6.2e-38 129.1 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_5 PF04998.17 CRK30766.1 - 7.8e-24 84.5 0.4 1.5e-23 83.6 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_3 PF04983.18 CRK30766.1 - 6e-15 55.5 0.0 1.3e-14 54.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 Senescence PF06911.12 CRK30766.1 - 0.03 14.6 0.3 0.54 10.6 0.1 2.2 2 0 0 2 2 2 0 Senescence-associated protein MIF4G_like_2 PF09090.11 CRK30766.1 - 0.037 13.5 0.1 0.05 13.1 0.1 1.1 1 0 0 1 1 1 0 MIF4G like DUF1236 PF06823.12 CRK30766.1 - 0.072 13.0 0.0 4.3 7.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1236) PI3_PI4_kinase PF00454.27 CRK30767.1 - 9.2e-72 241.8 0.1 1e-71 241.7 0.1 1.0 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PCI PF01399.27 CRK30768.1 - 2.3e-09 37.7 0.0 5.8e-09 36.4 0.0 1.7 2 0 0 2 2 2 1 PCI domain TPR_14 PF13428.6 CRK30768.1 - 0.072 13.9 0.8 13 6.9 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat AMP-binding PF00501.28 CRK30770.1 - 1.1e-36 126.4 0.1 1.3e-36 126.2 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CRK30770.1 - 2.7e-13 50.7 1.4 4e-13 50.1 0.5 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Glyco_transf_20 PF00982.21 CRK30771.1 - 4.2e-81 273.0 0.0 4.6e-81 272.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Clr5 PF14420.6 CRK30775.1 - 4.5e-17 62.0 0.4 4e-16 59.0 0.1 2.6 3 0 0 3 3 3 1 Clr5 domain TPR_14 PF13428.6 CRK30775.1 - 0.57 11.1 3.3 1.9 9.5 0.2 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat MFS_1 PF07690.16 CRK30776.1 - 6.6e-40 137.1 34.9 6.6e-40 137.1 34.9 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 CRK30776.1 - 2.3e-20 72.5 16.1 3.8e-20 71.8 16.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 CRK30776.1 - 2.7e-13 49.6 11.7 2.7e-13 49.6 11.7 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter ADH_zinc_N PF00107.26 CRK30779.1 - 4.1e-08 33.3 0.0 8.7e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CRK30779.1 - 0.00021 21.1 0.5 0.0011 18.8 0.1 2.2 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain AAA PF00004.29 CRK30782.1 - 1.7e-45 154.7 0.0 2.6e-45 154.1 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 CRK30782.1 - 1.9e-09 37.4 0.5 1.1e-08 34.8 0.1 2.2 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 CRK30782.1 - 8.8e-09 35.5 0.2 2.5e-08 34.0 0.2 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CRK30782.1 - 2.3e-08 34.3 0.0 4.2e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 CRK30782.1 - 1.1e-07 32.4 0.1 1.7e-05 25.2 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 CRK30782.1 - 2.3e-06 27.0 0.0 3.3e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 CRK30782.1 - 1.1e-05 25.7 0.9 0.0047 17.2 0.0 2.4 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 CRK30782.1 - 9.5e-05 22.2 0.0 0.00035 20.4 0.0 1.9 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 CRK30782.1 - 0.00029 21.4 0.0 0.00047 20.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 CRK30782.1 - 0.00033 20.2 0.1 0.0014 18.2 0.1 1.9 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_28 PF13521.6 CRK30782.1 - 0.00041 20.6 0.0 0.00064 20.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 CRK30782.1 - 0.00048 20.1 0.0 0.0083 16.1 0.0 2.1 1 1 1 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 CRK30782.1 - 0.00053 19.3 0.0 0.0011 18.2 0.0 1.5 1 1 0 1 1 1 1 TIP49 P-loop domain RNA_helicase PF00910.22 CRK30782.1 - 0.0011 19.3 0.0 0.002 18.5 0.0 1.5 1 0 0 1 1 1 1 RNA helicase NTPase_1 PF03266.15 CRK30782.1 - 0.0014 18.6 0.0 0.0062 16.5 0.0 1.9 2 0 0 2 2 2 1 NTPase NACHT PF05729.12 CRK30782.1 - 0.0018 18.2 0.3 0.065 13.2 0.0 2.6 2 1 0 3 3 3 1 NACHT domain AAA_14 PF13173.6 CRK30782.1 - 0.0018 18.3 0.0 0.003 17.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CRK30782.1 - 0.0027 17.5 0.1 0.0065 16.2 0.1 1.7 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 CRK30782.1 - 0.0029 17.0 0.2 0.0087 15.5 0.1 1.9 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CRK30782.1 - 0.0032 17.3 0.0 0.0093 15.8 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 CRK30782.1 - 0.0042 16.5 0.1 0.29 10.5 0.0 2.2 1 1 0 2 2 2 1 Bacterial TniB protein AAA_33 PF13671.6 CRK30782.1 - 0.0049 17.0 0.0 0.0093 16.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 CRK30782.1 - 0.0084 15.5 0.1 0.3 10.4 0.0 2.1 2 0 0 2 2 2 1 KaiC IstB_IS21 PF01695.17 CRK30782.1 - 0.0089 15.8 0.0 0.018 14.8 0.0 1.5 1 1 0 1 1 1 1 IstB-like ATP binding protein ATPase_2 PF01637.18 CRK30782.1 - 0.015 15.3 0.1 0.19 11.6 0.0 2.1 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 CRK30782.1 - 0.015 15.0 0.3 0.028 14.2 0.3 1.6 1 1 0 1 1 1 0 AAA domain Bac_DnaA PF00308.18 CRK30782.1 - 0.019 14.8 0.0 0.032 14.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein Sigma54_activat PF00158.26 CRK30782.1 - 0.023 14.4 0.2 0.66 9.7 0.0 2.4 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.6 CRK30782.1 - 0.038 13.6 0.7 0.12 12.0 0.1 1.8 1 1 1 2 2 2 0 AAA domain AAA_11 PF13086.6 CRK30782.1 - 0.043 13.6 0.0 0.059 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AFG1_ATPase PF03969.16 CRK30782.1 - 0.047 12.6 0.0 0.06 12.2 0.0 1.2 1 0 0 1 1 1 0 AFG1-like ATPase Zeta_toxin PF06414.12 CRK30782.1 - 0.061 12.6 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.6 CRK30782.1 - 0.07 13.5 0.3 0.2 12.0 0.1 1.8 2 0 0 2 2 1 0 AAA domain cobW PF02492.19 CRK30782.1 - 0.076 12.6 0.1 0.17 11.5 0.0 1.6 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 CRK30782.1 - 0.089 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Parvo_NS1 PF01057.17 CRK30782.1 - 0.13 11.3 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 RasGAP_C PF03836.15 CRK30783.1 - 3.6e-30 104.9 6.3 4.9e-30 104.5 6.3 1.2 1 0 0 1 1 1 1 RasGAP C-terminus CENP-F_leu_zip PF10473.9 CRK30783.1 - 0.044 13.8 3.6 0.086 12.9 3.6 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cnd1_N PF12922.7 CRK30787.1 - 1.8e-21 76.7 0.0 2.9e-21 76.0 0.0 1.4 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1, N-term T4_Gp59_N PF08993.10 CRK30787.1 - 0.075 13.5 0.1 4.6 7.7 0.0 2.4 2 1 0 2 2 2 0 T4 gene Gp59 loader of gp41 DNA helicase Pectinesterase PF01095.19 CRK30788.1 - 4.7e-22 78.1 5.6 5.7e-22 77.8 5.6 1.1 1 0 0 1 1 1 1 Pectinesterase Lon_C PF05362.13 CRK30789.1 - 2.5e-39 135.0 0.1 4e-39 134.3 0.1 1.3 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 CRK30789.1 - 0.048 14.1 0.0 0.12 12.8 0.0 1.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CENP-X PF09415.10 CRK30789.1 - 0.12 12.7 0.1 0.32 11.3 0.1 1.6 1 1 0 1 1 1 0 CENP-S associating Centromere protein X Cyt-b5 PF00173.28 CRK30790.1 - 0.08 13.1 0.0 0.26 11.4 0.0 1.9 1 1 0 1 1 1 0 Cytochrome b5-like Heme/Steroid binding domain 4HBT_3 PF13622.6 CRK30791.1 - 2.1e-40 139.6 1.9 2.6e-40 139.2 1.9 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 CRK30791.1 - 2.1e-05 24.4 0.0 0.0057 16.5 0.0 2.1 1 1 0 1 1 1 1 Acyl-CoA thioesterase Oxysterol_BP PF01237.18 CRK30792.1 - 1e-133 445.8 0.0 1e-133 445.8 0.0 2.4 3 0 0 3 3 3 1 Oxysterol-binding protein Ank_5 PF13857.6 CRK30792.1 - 4.9e-15 55.4 0.0 4.6e-09 36.4 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 CRK30792.1 - 2.4e-12 46.7 0.1 2.8e-05 24.4 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 CRK30792.1 - 4e-12 46.6 0.0 1.2e-06 29.0 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CRK30792.1 - 4.3e-12 46.3 0.0 2.3e-07 31.2 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CRK30792.1 - 4.8e-11 41.9 0.0 0.00013 22.1 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat PH PF00169.29 CRK30792.1 - 7.2e-11 42.5 0.3 1.5e-10 41.5 0.3 1.6 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 CRK30792.1 - 2.8e-08 33.9 0.5 7.9e-08 32.5 0.5 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 CRK30792.1 - 0.00063 20.1 2.2 0.0018 18.7 2.2 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain Glyco_hydro_18 PF00704.28 CRK30793.1 - 5.5e-17 62.5 0.0 2.3e-16 60.4 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Amino_oxidase PF01593.24 CRK30794.1 - 8.6e-26 91.2 0.1 5.4e-23 82.0 0.0 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pirin PF02678.16 CRK30794.1 - 1.9e-25 88.9 1.6 7.4e-25 87.0 1.6 2.0 1 1 0 1 1 1 1 Pirin NAD_binding_8 PF13450.6 CRK30794.1 - 5e-15 55.5 0.2 2.4e-14 53.3 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CRK30794.1 - 1.3e-11 44.8 0.1 5.9e-11 42.5 0.1 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CRK30794.1 - 2.3e-10 40.2 0.6 4.2e-06 26.2 0.0 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CRK30794.1 - 1.7e-07 30.7 4.0 0.00013 21.2 3.0 2.5 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.14 CRK30794.1 - 1.1e-06 27.7 0.8 0.00093 18.0 0.9 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.27 CRK30794.1 - 7.5e-05 23.2 3.0 0.035 14.6 1.0 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CRK30794.1 - 0.00017 21.1 0.1 0.00067 19.1 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase MCRA PF06100.11 CRK30794.1 - 0.00056 18.8 0.0 0.086 11.6 0.0 2.1 2 0 0 2 2 2 1 MCRA family Pyr_redox_3 PF13738.6 CRK30794.1 - 0.0024 17.2 1.4 0.0041 16.4 1.4 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Cupin_2 PF07883.11 CRK30794.1 - 0.0069 16.1 2.6 0.29 10.9 0.7 3.0 2 1 0 2 2 2 1 Cupin domain ApbA PF02558.16 CRK30794.1 - 0.0071 16.0 0.2 0.016 14.9 0.2 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.6 CRK30794.1 - 0.011 15.7 1.7 0.76 9.8 0.3 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.17 CRK30794.1 - 0.013 14.7 0.2 0.025 13.8 0.2 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.19 CRK30794.1 - 0.039 13.2 1.3 0.059 12.6 0.4 1.7 2 0 0 2 2 2 0 FAD binding domain 3HCDH_N PF02737.18 CRK30794.1 - 0.041 13.7 0.8 0.074 12.9 0.8 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 CRK30794.1 - 0.055 12.5 2.9 0.072 12.1 0.7 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein YARHG PF13308.6 CRK30794.1 - 0.057 13.3 0.2 1.9 8.4 0.1 2.8 3 0 0 3 3 2 0 YARHG domain GIDA PF01134.22 CRK30794.1 - 0.076 12.1 4.9 0.082 12.0 2.0 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A adh_short PF00106.25 CRK30794.1 - 0.11 11.9 1.5 0.31 10.5 1.0 1.9 2 0 0 2 2 2 0 short chain dehydrogenase GDI PF00996.18 CRK30794.1 - 0.15 10.5 0.0 8.3 4.8 0.0 2.2 2 0 0 2 2 2 0 GDP dissociation inhibitor SQS_PSY PF00494.19 CRK30795.1 - 4.7e-62 209.9 1.2 7.7e-62 209.2 1.2 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase 4HBT PF03061.22 CRK30796.1 - 1e-06 29.0 0.2 2.8e-06 27.6 0.2 1.8 1 0 0 1 1 1 1 Thioesterase superfamily FAD_binding_7 PF03441.14 CRK30797.1 - 3.2e-48 163.9 1.0 5.1e-48 163.2 1.0 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 CRK30797.1 - 2.1e-20 73.4 0.0 3.5e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase zf-C2H2 PF00096.26 CRK30799.1 - 8e-05 22.9 23.8 0.44 11.1 5.0 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CRK30799.1 - 0.00016 22.3 20.3 0.29 12.1 5.2 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CRK30799.1 - 0.16 12.0 8.6 2.2 8.4 3.8 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger Adeno_E3_CR2 PF02439.15 CRK30799.1 - 0.18 11.6 1.9 0.33 10.8 1.9 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 KH_6 PF15985.5 CRK30800.1 - 9.3e-17 61.1 0.2 3.2e-16 59.4 0.1 2.0 2 0 0 2 2 2 1 KH domain Rrp40_N PF18311.1 CRK30800.1 - 5.4e-16 58.3 2.9 7.4e-16 57.8 0.9 2.2 3 0 0 3 3 3 1 Exosome complex exonuclease Rrp40 N-terminal domain HSP70 PF00012.20 CRK30801.1 - 2.4e-77 260.5 3.8 3.7e-77 259.9 3.8 1.3 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CRK30801.1 - 5.5e-10 38.6 0.2 9.6e-10 37.8 0.2 1.4 1 0 0 1 1 1 1 MreB/Mbl protein PilM_2 PF11104.8 CRK30801.1 - 0.031 13.3 0.1 2.7 6.9 0.0 2.3 2 0 0 2 2 2 0 Type IV pilus assembly protein PilM; MFMR_assoc PF16596.5 CRK30801.1 - 0.15 12.5 0.5 0.36 11.3 0.5 1.6 1 0 0 1 1 1 0 Disordered region downstream of MFMR Cwf_Cwc_15 PF04889.12 CRK30801.1 - 0.16 11.6 4.9 0.34 10.6 4.9 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PBP1_TM PF14812.6 CRK30801.1 - 0.51 10.7 6.1 1.2 9.6 6.1 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DNA_pol_phi PF04931.13 CRK30801.1 - 0.54 8.3 5.6 0.86 7.6 5.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi Tautomerase PF01361.21 CRK30801.1 - 0.68 9.9 4.3 1 9.4 0.5 2.8 2 1 1 3 3 3 0 Tautomerase enzyme NOA36 PF06524.12 CRK30801.1 - 8.8 5.5 7.8 19 4.5 7.8 1.5 1 0 0 1 1 1 0 NOA36 protein NT-C2 PF10358.9 CRK30802.1 - 4e-24 85.0 0.0 7.5e-20 71.1 0.0 2.3 2 0 0 2 2 2 2 N-terminal C2 in EEIG1 and EHBP1 proteins Rrp40_N PF18311.1 CRK30802.1 - 1.3e-15 57.1 0.9 3.2e-15 55.8 0.9 1.8 1 0 0 1 1 1 1 Exosome complex exonuclease Rrp40 N-terminal domain KH_6 PF15985.5 CRK30802.1 - 0.0059 16.9 0.0 0.016 15.6 0.0 1.7 1 0 0 1 1 1 1 KH domain HSP70 PF00012.20 CRK30803.1 - 1.1e-77 261.6 2.8 1.1e-77 261.6 2.8 1.4 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 CRK30803.1 - 2.3e-10 39.8 0.3 4.4e-10 38.9 0.3 1.5 1 1 0 1 1 1 1 MreB/Mbl protein CENP-B_dimeris PF09026.10 CRK30803.1 - 0.025 15.0 2.3 0.062 13.7 2.3 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Cwf_Cwc_15 PF04889.12 CRK30803.1 - 0.035 13.8 2.5 0.069 12.9 2.5 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF3221 PF11518.8 CRK30803.1 - 0.065 13.6 0.3 0.17 12.3 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3221) FAM176 PF14851.6 CRK30803.1 - 0.2 11.3 0.5 0.44 10.2 0.5 1.5 1 0 0 1 1 1 0 FAM176 family DNA_pol_phi PF04931.13 CRK30803.1 - 4 5.4 5.1 6 4.8 5.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi NT-C2 PF10358.9 CRK30804.1 - 4.8e-21 75.0 0.0 1.4e-16 60.5 0.0 2.2 2 0 0 2 2 2 2 N-terminal C2 in EEIG1 and EHBP1 proteins POP1 PF06978.11 CRK30805.1 - 2.3e-74 249.8 18.0 2.3e-74 249.8 18.0 1.7 2 0 0 2 2 2 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 CRK30805.1 - 6.3e-27 93.8 0.1 1.8e-26 92.3 0.1 1.9 1 0 0 1 1 1 1 POPLD (NUC188) domain EAF PF09816.9 CRK30806.1 - 1.3e-21 76.9 1.6 1.9e-21 76.4 0.1 2.1 2 0 0 2 2 2 1 RNA polymerase II transcription elongation factor mRNA_cap_enzyme PF01331.19 CRK30806.1 - 0.17 11.7 0.0 0.28 11.0 0.0 1.2 1 0 0 1 1 1 0 mRNA capping enzyme, catalytic domain MmgE_PrpD PF03972.14 CRK30807.1 - 5.6e-147 489.8 0.0 7.2e-147 489.5 0.0 1.1 1 0 0 1 1 1 1 MmgE/PrpD family SH3_1 PF00018.28 CRK30807.1 - 2e-14 52.9 0.0 5.2e-14 51.6 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CRK30807.1 - 7.1e-09 35.4 0.0 1.3e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CRK30807.1 - 4.3e-07 29.5 0.0 7.5e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Pro-rich PF15240.6 CRK30807.1 - 0.0075 16.6 20.8 0.0075 16.6 20.8 2.4 2 0 0 2 2 2 1 Proline-rich DUF910 PF06014.11 CRK30807.1 - 0.077 13.0 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF910) ABC_tran_Xtn PF12848.7 CRK30808.1 - 0.014 15.4 6.1 0.036 14.1 6.1 1.7 1 0 0 1 1 1 0 ABC transporter DUF2203 PF09969.9 CRK30808.1 - 2.9 8.6 6.2 5.2 7.8 4.4 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) MFS_1 PF07690.16 CRK30809.1 - 6.3e-23 81.3 32.0 6.3e-23 81.3 32.0 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK30809.1 - 2.2e-09 36.7 18.9 4.4e-09 35.7 18.9 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter IBR PF01485.21 CRK30809.1 - 2.2e-08 34.2 14.1 4.6e-07 30.0 8.4 2.4 2 0 0 2 2 2 2 IBR domain, a half RING-finger domain NS3_envE PF02723.14 CRK30810.1 - 0.091 12.8 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Non-structural protein NS3/Small envelope protein E DUF5597 PF18120.1 CRK30813.1 - 3.2e-25 88.8 0.0 4.9e-25 88.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5597) Glyco_hydro_42 PF02449.15 CRK30813.1 - 2.6e-09 36.9 0.1 5.3e-09 35.9 0.0 1.5 2 0 0 2 2 2 1 Beta-galactosidase Glyco_hydro_35 PF01301.19 CRK30813.1 - 5.7e-06 26.2 0.0 0.0063 16.2 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 35 Glyco_hydro_10 PF00331.20 CRK30813.1 - 0.1 11.7 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 10 SET PF00856.28 CRK30814.1 - 0.0078 16.6 0.0 0.014 15.8 0.0 1.5 1 0 0 1 1 1 1 SET domain POP1 PF06978.11 CRK30815.1 - 4.2e-75 252.3 19.1 8.7e-75 251.2 19.1 1.6 1 0 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 CRK30815.1 - 4.8e-27 94.1 0.1 1.4e-26 92.6 0.1 1.9 1 0 0 1 1 1 1 POPLD (NUC188) domain EAF PF09816.9 CRK30816.1 - 1.1e-21 77.1 0.1 1.1e-21 77.1 0.1 2.0 2 0 0 2 2 2 1 RNA polymerase II transcription elongation factor mRNA_cap_enzyme PF01331.19 CRK30816.1 - 0.17 11.7 0.0 0.28 11.0 0.0 1.2 1 0 0 1 1 1 0 mRNA capping enzyme, catalytic domain MmgE_PrpD PF03972.14 CRK30817.1 - 2e-99 333.1 0.0 3.4e-99 332.3 0.0 1.3 1 0 0 1 1 1 1 MmgE/PrpD family DUF910 PF06014.11 CRK30817.1 - 0.11 12.5 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF910) IBR PF01485.21 CRK30819.1 - 4.5e-12 46.0 29.7 2.5e-07 30.8 8.4 3.6 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 CRK30819.1 - 0.0053 17.1 7.3 0.0053 17.1 7.3 3.5 2 1 1 3 3 3 1 Ring finger domain F-box-like_2 PF13013.6 CRK30819.1 - 0.057 13.4 0.4 3.4 7.7 0.0 2.8 2 0 0 2 2 2 0 F-box-like domain zf-RING_UBOX PF13445.6 CRK30819.1 - 0.68 10.0 12.7 0.11 12.6 7.9 2.3 2 0 0 2 2 2 0 RING-type zinc-finger Cyclin PF08613.11 CRK30820.1 - 6.2e-13 49.4 10.2 3.2e-06 27.6 0.0 3.3 3 1 0 3 3 3 2 Cyclin Cyclin_N PF00134.23 CRK30820.1 - 8.1e-07 28.8 0.1 0.058 13.2 0.0 2.6 2 0 0 2 2 2 2 Cyclin, N-terminal domain Interferon PF00143.19 CRK30820.1 - 0.28 11.3 0.5 34 4.6 0.1 2.3 2 0 0 2 2 2 0 Interferon alpha/beta domain Glyco_hydro_42 PF02449.15 CRK30821.1 - 9.1e-09 35.1 0.0 1.9e-08 34.1 0.0 1.5 1 1 0 1 1 1 1 Beta-galactosidase Glyco_hydro_35 PF01301.19 CRK30821.1 - 1.4e-05 24.9 0.0 0.009 15.7 0.0 2.0 2 0 0 2 2 2 2 Glycosyl hydrolases family 35 Glyco_hydro_10 PF00331.20 CRK30821.1 - 0.11 11.7 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 10 Fungal_trans PF04082.18 CRK30822.1 - 2.6e-32 111.9 0.0 6e-32 110.7 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK30822.1 - 4e-10 39.6 11.2 4e-10 39.6 11.2 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Actin PF00022.19 CRK30823.1 - 2.1e-127 425.1 0.0 8.6e-127 423.1 0.0 1.7 1 1 0 1 1 1 1 Actin PIG-F PF06699.11 CRK30824.1 - 8.2e-92 306.3 16.6 7e-64 215.3 3.7 2.2 2 0 0 2 2 2 2 GPI biosynthesis protein family Pig-F Pmp3 PF01679.17 CRK30824.1 - 5.3e-23 81.0 8.1 5.3e-23 81.0 8.1 2.8 2 1 0 2 2 2 1 Proteolipid membrane potential modulator ADP_ribosyl_GH PF03747.14 CRK30824.1 - 0.69 9.6 3.7 15 5.2 0.3 2.3 2 0 0 2 2 2 0 ADP-ribosylglycohydrolase Fungal_trans PF04082.18 CRK30825.1 - 4e-32 111.3 0.0 4e-32 111.3 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain TFIIA PF03153.13 CRK30825.1 - 0.23 11.4 26.0 0.36 10.8 26.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 CRK30825.1 - 0.33 10.5 22.3 0.6 9.7 22.3 1.3 1 0 0 1 1 1 0 Spt20 family Med3 PF11593.8 CRK30825.1 - 1.8 7.7 19.7 3.2 6.8 19.3 1.5 1 1 0 1 1 1 0 Mediator complex subunit 3 fungal eIF-3_zeta PF05091.12 CRK30825.1 - 2.3 7.1 12.5 3.4 6.5 12.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Ndc1_Nup PF09531.10 CRK30825.1 - 6.4 5.3 10.2 10 4.7 10.2 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PIG-F PF06699.11 CRK30826.1 - 0.0001 22.5 0.2 0.00014 22.1 0.2 1.2 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F TRP PF06011.12 CRK30827.1 - 3.3e-17 62.3 13.1 4.4e-12 45.5 13.3 2.2 2 0 0 2 2 2 2 Transient receptor potential (TRP) ion channel GDPD PF03009.17 CRK30828.1 - 1.5e-24 87.1 0.0 9.2e-19 68.2 0.0 2.1 1 1 1 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family DUF3602 PF12223.8 CRK30829.1 - 2.5e-16 60.0 18.2 2.3e-13 50.5 5.7 2.4 2 1 1 3 3 3 2 Protein of unknown function (DUF3602) FAM199X PF15814.5 CRK30829.1 - 8 5.4 8.8 10 5.0 8.8 1.2 1 0 0 1 1 1 0 Protein family FAM199X IFRD PF05004.13 CRK30831.1 - 8e-71 238.6 8.0 1e-70 238.3 8.0 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) HEAT_EZ PF13513.6 CRK30831.1 - 0.078 13.5 0.9 21 5.8 0.0 3.4 3 1 1 4 4 4 0 HEAT-like repeat RAP1 PF07218.11 CRK30831.1 - 5 5.3 5.4 6.8 4.8 5.4 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) FHA PF00498.26 CRK30832.1 - 9.3e-14 51.5 0.0 2e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 FHA domain WD40 PF00400.32 CRK30833.1 - 1.3e-39 133.4 19.2 5.5e-10 39.7 0.0 8.0 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK30833.1 - 4.9e-14 52.4 0.7 0.0092 16.3 0.0 4.9 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CRK30833.1 - 4e-08 32.6 0.4 0.23 10.4 0.0 4.7 2 1 2 4 4 4 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CRK30833.1 - 1.3e-06 27.4 2.5 0.5 8.9 0.1 4.3 3 1 0 3 3 3 3 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 CRK30833.1 - 4.2e-05 22.7 0.2 4.2e-05 22.7 0.2 2.8 3 1 1 4 4 4 1 Partner and localizer of BRCA2 WD40 domain Frtz PF11768.8 CRK30833.1 - 0.00055 18.4 0.0 0.0027 16.1 0.0 2.0 2 1 1 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz HPS3_N PF14761.6 CRK30833.1 - 0.0023 17.5 0.0 0.049 13.2 0.0 2.5 2 1 1 3 3 3 1 Hermansky-Pudlak syndrome 3 DUF1513 PF07433.11 CRK30833.1 - 0.004 16.3 0.5 2.2 7.3 0.0 3.4 1 1 2 4 4 4 1 Protein of unknown function (DUF1513) Hira PF07569.11 CRK30833.1 - 0.073 12.8 1.3 24 4.6 0.2 3.2 1 1 1 2 2 2 0 TUP1-like enhancer of split Pkinase PF00069.25 CRK30834.1 - 2.5e-12 46.7 0.0 7.1e-12 45.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain HEAT PF02985.22 CRK30834.1 - 1.3e-08 34.3 1.8 0.084 13.2 0.0 4.8 5 1 0 5 5 5 3 HEAT repeat Cnd1 PF12717.7 CRK30834.1 - 3.4e-05 24.0 0.0 0.00011 22.3 0.0 1.7 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 CRK30834.1 - 5.7e-05 23.5 0.0 0.17 12.4 0.0 3.3 3 0 0 3 3 3 2 HEAT-like repeat Pkinase_Tyr PF07714.17 CRK30834.1 - 0.00011 21.6 0.0 0.00018 20.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.6 CRK30834.1 - 0.00042 20.6 0.2 0.67 10.4 0.0 3.9 3 1 2 5 5 5 2 HEAT repeats Aconitase PF00330.20 CRK30838.1 - 1.3e-142 476.1 0.0 2e-142 475.4 0.0 1.3 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 CRK30838.1 - 4.1e-38 130.7 0.0 7.7e-38 129.8 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain N_BRCA1_IG PF16158.5 CRK30838.1 - 3.8e-35 120.7 0.0 1e-34 119.3 0.0 1.8 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene COPIIcoated_ERV PF07970.12 CRK30838.1 - 1.7e-32 113.1 0.0 1.7e-32 113.1 0.0 2.3 2 0 0 2 2 2 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 CRK30838.1 - 4.3e-24 84.7 0.0 9.3e-24 83.6 0.0 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) ZZ PF00569.17 CRK30838.1 - 2.3e-16 59.3 66.2 3e-05 23.7 11.3 4.6 4 0 0 4 4 4 4 Zinc finger, ZZ type DUF521 PF04412.13 CRK30838.1 - 0.079 11.7 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) C1_2 PF03107.16 CRK30838.1 - 1.3 9.4 56.5 0.14 12.5 11.7 4.4 4 0 0 4 4 4 0 C1 domain End3 PF12761.7 CRK30840.1 - 0.084 13.0 0.3 0.15 12.2 0.3 1.3 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 F-box-like PF12937.7 CRK30840.1 - 0.2 11.6 0.8 0.96 9.4 0.1 2.5 3 0 0 3 3 3 0 F-box-like Btz PF09405.10 CRK30842.1 - 3.4e-28 98.5 1.6 8.4e-28 97.2 1.6 1.7 1 0 0 1 1 1 1 CASC3/Barentsz eIF4AIII binding Aminotran_4 PF01063.19 CRK30844.1 - 4.2e-14 53.0 0.0 5.9e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV TPR_1 PF00515.28 CRK30846.1 - 5.5e-47 155.7 26.6 3.3e-06 26.7 0.0 11.4 11 1 0 11 11 11 10 Tetratricopeptide repeat TPR_2 PF07719.17 CRK30846.1 - 6.5e-44 144.5 22.8 0.0001 22.1 0.0 11.3 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_16 PF13432.6 CRK30846.1 - 3.3e-27 94.8 6.9 1.7e-06 28.5 0.4 7.7 6 1 2 8 8 8 5 Tetratricopeptide repeat TPR_11 PF13414.6 CRK30846.1 - 9.2e-27 92.5 21.6 1.9e-05 24.2 0.0 8.8 6 2 3 9 9 9 6 TPR repeat TPR_8 PF13181.6 CRK30846.1 - 1.9e-26 90.0 23.2 0.0045 17.1 0.0 10.7 11 0 0 11 11 10 6 Tetratricopeptide repeat TPR_17 PF13431.6 CRK30846.1 - 2.3e-25 87.1 7.3 0.00013 22.1 0.0 9.4 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_12 PF13424.6 CRK30846.1 - 4.8e-23 81.2 26.6 6.1e-05 23.2 0.4 9.0 4 3 4 8 8 8 6 Tetratricopeptide repeat TPR_19 PF14559.6 CRK30846.1 - 2e-16 60.2 18.8 6.8e-06 26.5 1.7 6.6 5 2 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 CRK30846.1 - 2.4e-15 55.9 16.8 0.0042 17.8 0.3 9.3 4 3 7 11 11 10 3 Tetratricopeptide repeat TPR_9 PF13371.6 CRK30846.1 - 2.5e-15 56.4 9.5 5.1e-07 29.7 0.2 5.5 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 CRK30846.1 - 1.6e-11 43.3 18.3 0.033 14.2 0.2 8.9 9 1 1 10 10 8 2 Tetratricopeptide repeat TPR_10 PF13374.6 CRK30846.1 - 4.2e-10 39.2 13.3 0.026 14.4 0.4 8.7 9 0 0 9 9 8 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CRK30846.1 - 1.1e-08 35.2 14.5 0.00012 22.2 0.7 5.9 2 2 5 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 CRK30846.1 - 2.7e-08 33.6 2.4 1.5e-07 31.2 2.4 2.1 1 1 0 1 1 1 1 MalT-like TPR region SHNi-TPR PF10516.9 CRK30846.1 - 1.3e-06 27.7 9.4 0.12 11.9 0.0 5.6 6 0 0 6 6 6 2 SHNi-TPR TPR_15 PF13429.6 CRK30846.1 - 8e-05 22.0 5.5 0.6 9.3 0.1 4.8 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 CRK30846.1 - 0.00027 21.4 22.1 13 6.7 0.7 9.3 11 0 0 11 11 8 0 Tetratricopeptide repeat TAF1_subA PF14929.6 CRK30846.1 - 0.00077 19.0 1.1 0.014 14.9 0.3 2.4 1 1 1 2 2 2 1 TAF RNA Polymerase I subunit A DUF3856 PF12968.7 CRK30846.1 - 0.0082 16.2 5.1 6.8 6.8 0.0 5.8 6 2 0 7 7 6 0 Domain of Unknown Function (DUF3856) HrpB1_HrpK PF09613.10 CRK30846.1 - 0.0093 15.6 0.5 0.097 12.3 0.5 2.3 1 1 1 2 2 2 1 Bacterial type III secretion protein (HrpB1_HrpK) MAS20 PF02064.15 CRK30846.1 - 0.0099 16.0 7.1 0.66 10.1 0.9 4.1 4 1 0 4 4 4 1 MAS20 protein import receptor TPR_4 PF07721.14 CRK30846.1 - 0.012 16.2 0.3 41 5.2 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat AP3D1 PF06375.11 CRK30846.1 - 0.02 15.1 2.9 0.044 14.0 2.9 1.5 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 FAT PF02259.23 CRK30846.1 - 0.06 12.5 0.5 16 4.6 0.5 3.2 1 1 2 3 3 3 0 FAT domain SPO22 PF08631.10 CRK30846.1 - 0.088 12.3 2.2 8.8 5.7 0.0 3.6 3 1 2 5 5 5 0 Meiosis protein SPO22/ZIP4 like MIT PF04212.18 CRK30846.1 - 0.62 10.2 17.1 13 5.9 0.1 6.4 7 0 0 7 7 6 0 MIT (microtubule interacting and transport) domain NARP1 PF12569.8 CRK30846.1 - 1.1 8.0 25.8 0.31 9.9 0.3 5.0 2 2 1 4 4 4 0 NMDA receptor-regulated protein 1 PPR PF01535.20 CRK30846.1 - 1.2 9.5 3.0 21 5.7 0.0 4.2 4 0 0 4 4 3 0 PPR repeat Sel1 PF08238.12 CRK30846.1 - 2.3 9.0 7.2 1.8 9.4 0.1 4.3 5 0 0 5 5 3 0 Sel1 repeat TPR_20 PF14561.6 CRK30846.1 - 2.6 8.4 12.9 0.21 11.9 0.3 4.6 5 2 0 5 5 4 0 Tetratricopeptide repeat Syntaxin PF00804.25 CRK30848.1 - 1.6e-25 89.9 16.1 1.6e-25 89.9 16.1 1.4 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.19 CRK30848.1 - 8.9e-12 44.8 3.0 8.9e-12 44.8 3.0 2.1 2 0 0 2 2 1 1 SNARE domain Muted PF14942.6 CRK30848.1 - 0.013 15.8 7.1 0.013 15.8 7.1 2.5 3 0 0 3 3 2 0 Organelle biogenesis, Muted-like protein DUF2951 PF11166.8 CRK30848.1 - 0.048 13.9 0.2 0.048 13.9 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) DUF3094 PF11293.8 CRK30848.1 - 0.06 13.1 0.1 0.15 11.8 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3094) DUF2207 PF09972.9 CRK30848.1 - 0.13 11.0 2.4 0.14 10.9 0.1 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) PBP1_TM PF14812.6 CRK30848.1 - 0.28 11.6 0.1 0.28 11.6 0.1 2.4 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Methyltransf_23 PF13489.6 CRK30848.1 - 0.35 10.7 2.8 0.56 10.0 0.7 2.2 2 2 0 2 2 2 0 Methyltransferase domain Allexi_40kDa PF05549.11 CRK30848.1 - 0.63 9.5 14.2 0.23 11.0 6.7 2.2 2 0 0 2 2 2 0 Allexivirus 40kDa protein SKA2 PF16740.5 CRK30848.1 - 1.3 8.8 17.0 0.27 11.0 3.4 3.0 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 2 V-SNARE PF05008.15 CRK30848.1 - 1.9 8.9 15.3 1.2 9.6 1.1 3.2 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus DUF4094 PF13334.6 CRK30848.1 - 3.6 8.1 10.1 5.3 7.5 0.1 3.2 1 1 1 3 3 3 0 Domain of unknown function (DUF4094) JIP_LZII PF16471.5 CRK30848.1 - 4 7.7 14.1 1.9 8.7 0.1 3.8 2 1 2 4 4 4 0 JNK-interacting protein leucine zipper II DUF1192 PF06698.11 CRK30848.1 - 6.7 6.8 9.4 15 5.7 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) Brix PF04427.18 CRK30850.1 - 2.3e-26 93.1 0.3 5.7e-26 91.8 0.3 1.6 1 1 0 1 1 1 1 Brix domain UPF1_Zn_bind PF09416.10 CRK30852.1 - 1.8e-71 239.1 2.0 6.4e-71 237.2 1.0 2.1 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 CRK30852.1 - 2.6e-59 200.2 0.0 4.8e-59 199.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CRK30852.1 - 8.7e-54 183.0 2.7 3.3e-30 105.7 0.2 2.2 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 CRK30852.1 - 1.1e-31 108.9 0.0 2e-31 108.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 CRK30852.1 - 5.4e-14 52.4 0.9 1.3e-12 47.9 0.9 2.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CRK30852.1 - 9.7e-10 38.9 0.1 3.3e-09 37.2 0.1 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 CRK30852.1 - 5.3e-06 26.5 0.0 1e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PIF1 PF05970.14 CRK30852.1 - 0.0002 20.7 0.1 0.14 11.2 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase DUF2075 PF09848.9 CRK30852.1 - 0.00029 20.2 0.1 0.0053 16.1 0.0 2.5 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 CRK30852.1 - 0.0005 20.0 0.0 0.00096 19.0 0.0 1.5 1 0 0 1 1 1 1 Helicase Viral_helicase1 PF01443.18 CRK30852.1 - 0.00088 19.1 0.2 2.5 7.8 0.0 2.9 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DEAD PF00270.29 CRK30852.1 - 0.0021 17.9 0.3 0.0044 16.8 0.2 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase UvrD-helicase PF00580.21 CRK30852.1 - 0.0039 16.8 0.1 0.064 12.8 0.1 2.2 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain ATPase PF06745.13 CRK30852.1 - 0.0072 15.7 0.0 0.017 14.5 0.0 1.6 2 0 0 2 2 2 1 KaiC AAA_10 PF12846.7 CRK30852.1 - 0.033 13.1 0.0 0.055 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain SRP54 PF00448.22 CRK30852.1 - 0.037 13.6 0.0 0.067 12.8 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_16 PF13191.6 CRK30852.1 - 0.059 13.7 0.6 0.12 12.8 0.1 1.7 2 0 0 2 2 1 0 AAA ATPase domain PhoH PF02562.16 CRK30852.1 - 0.092 12.2 0.0 0.24 10.8 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein AAA_22 PF13401.6 CRK30852.1 - 0.1 12.8 0.1 0.42 10.9 0.0 2.0 2 0 0 2 2 1 0 AAA domain Dicty_REP PF05086.12 CRK30854.1 - 0.56 8.1 5.9 0.75 7.7 5.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Glyco_hydro_47 PF01532.20 CRK30855.1 - 5.8e-161 536.4 0.1 7.3e-161 536.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DnaJ PF00226.31 CRK30855.1 - 4.2e-31 106.9 3.0 1.3e-17 63.6 0.2 2.6 2 0 0 2 2 2 2 DnaJ domain Asn_synthase PF00733.21 CRK30856.1 - 2.2e-90 303.9 0.2 9.3e-52 176.8 0.0 2.2 1 1 1 2 2 2 2 Asparagine synthase Porin_3 PF01459.22 CRK30856.1 - 9.4e-65 218.8 9.9 3.3e-55 187.4 3.6 2.2 2 0 0 2 2 2 2 Eukaryotic porin GATase_7 PF13537.6 CRK30856.1 - 1.4e-63 212.3 0.0 9.2e-35 119.2 0.0 2.4 2 0 0 2 2 2 2 Glutamine amidotransferase domain GATase_6 PF13522.6 CRK30856.1 - 1.8e-50 170.6 0.0 1.3e-24 86.9 0.0 2.3 2 0 0 2 2 2 2 Glutamine amidotransferase domain DUF3700 PF12481.8 CRK30856.1 - 4.3e-10 39.4 0.0 7e-07 28.9 0.0 2.4 2 0 0 2 2 2 2 Aluminium induced protein NAD_synthase PF02540.17 CRK30856.1 - 0.0027 16.9 0.0 0.01 14.9 0.0 1.9 1 1 0 1 1 1 1 NAD synthase QueC PF06508.13 CRK30856.1 - 0.018 14.5 0.0 0.036 13.6 0.0 1.4 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC DNA_mis_repair PF01119.19 CRK30856.1 - 0.078 12.6 0.0 12 5.6 0.0 2.5 2 0 0 2 2 2 0 DNA mismatch repair protein, C-terminal domain UQ_con PF00179.26 CRK30857.1 - 3.9e-49 165.9 0.1 4.4e-49 165.7 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CRK30857.1 - 4.9e-05 23.0 0.0 5.3e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 CRK30857.1 - 0.01 16.1 1.9 0.024 14.9 1.9 1.8 1 1 0 1 1 1 0 RWD domain Pex19 PF04614.12 CRK30858.1 - 2.7e-78 263.1 11.6 2.7e-78 263.1 11.6 1.6 2 0 0 2 2 2 1 Pex19 protein family PP2C_C PF07830.13 CRK30858.1 - 0.091 13.2 0.5 11 6.6 0.0 3.1 3 0 0 3 3 3 0 Protein serine/threonine phosphatase 2C, C-terminal domain FKBP_N PF01346.18 CRK30858.1 - 2.5 9.1 10.3 23 6.0 3.6 3.3 1 1 1 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase GET2 PF08690.10 CRK30858.1 - 4.1 7.0 20.0 0.12 12.0 7.1 3.2 1 1 1 2 2 2 0 GET complex subunit GET2 Ribosomal_L36e PF01158.18 CRK30859.1 - 0.056 13.7 0.5 0.087 13.1 0.5 1.3 1 0 0 1 1 1 0 Ribosomal protein L36e bZIP_C PF12498.8 CRK30859.1 - 1.7 9.6 7.5 0.16 12.9 0.7 2.3 2 1 0 2 2 2 0 Basic leucine-zipper C terminal Na_H_Exchanger PF00999.21 CRK30860.1 - 0.0025 16.7 2.2 0.82 8.4 0.6 2.2 2 0 0 2 2 2 2 Sodium/hydrogen exchanger family ABC1 PF03109.16 CRK30861.1 - 5.5e-32 110.4 0.0 9.4e-32 109.7 0.0 1.4 1 0 0 1 1 1 1 ABC1 family Rad52_Rad22 PF04098.15 CRK30862.1 - 1.4e-60 203.7 0.0 1.9e-60 203.2 0.0 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein RRM_1 PF00076.22 CRK30863.1 - 9e-16 57.5 0.0 4.5e-10 39.2 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CRK30863.1 - 0.0038 17.3 0.1 0.013 15.6 0.1 1.9 2 0 0 2 2 2 1 RNA recognition motif RPA43_OB PF17875.1 CRK30863.1 - 0.12 13.0 10.3 2.5 8.8 0.6 2.7 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I Nup35_RRM_2 PF14605.6 CRK30863.1 - 0.13 12.3 0.0 0.74 9.9 0.0 2.1 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Gln-synt_C PF00120.24 CRK30864.1 - 2.3e-71 240.6 0.0 3.5e-71 240.0 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.14 CRK30864.1 - 5.1e-09 36.3 0.0 1.1e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase Gln-synt_N_2 PF16952.5 CRK30864.1 - 0.0086 15.9 0.0 0.021 14.7 0.0 1.6 1 0 0 1 1 1 1 Glutamine synthetase N-terminal domain But2 PF09792.9 CRK30865.1 - 0.00034 21.0 0.1 0.00087 19.7 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain Glyco_hydro_76 PF03663.14 CRK30866.1 - 7.6e-110 367.9 4.8 8.7e-110 367.7 4.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 FokI_N PF02981.15 CRK30866.1 - 0.41 10.8 1.9 30 4.8 0.0 2.4 1 1 1 2 2 2 0 Restriction endonuclease FokI, recognition domain zf-MYND PF01753.18 CRK30867.1 - 4.3e-10 39.5 9.8 6.3e-10 39.0 9.8 1.2 1 0 0 1 1 1 1 MYND finger MFS_1 PF07690.16 CRK30868.1 - 3.7e-32 111.6 34.4 3.7e-32 111.6 34.4 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK30868.1 - 0.0042 16.0 19.9 0.011 14.6 19.7 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter UNC-93 PF05978.16 CRK30868.1 - 0.18 11.5 4.2 0.43 10.3 3.7 1.8 1 1 0 1 1 1 0 Ion channel regulatory protein UNC-93 zf-C2H2 PF00096.26 CRK30869.1 - 0.00017 21.8 13.0 0.068 13.7 2.3 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CRK30869.1 - 0.017 15.9 10.3 3.8 8.6 1.3 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger DUF3450 PF11932.8 CRK30869.1 - 0.02 14.2 1.3 0.03 13.6 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) ZapB PF06005.12 CRK30869.1 - 0.022 15.2 1.3 0.044 14.2 1.3 1.5 1 0 0 1 1 1 0 Cell division protein ZapB HAUS5 PF14817.6 CRK30869.1 - 0.035 12.9 0.9 0.045 12.5 0.9 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 zf-C2H2_aberr PF17017.5 CRK30869.1 - 0.057 13.6 0.3 0.5 10.5 0.0 2.2 2 0 0 2 2 2 0 Aberrant zinc-finger GAS PF13851.6 CRK30869.1 - 0.08 12.3 2.4 0.12 11.7 2.4 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding CDPS PF16715.5 CRK30869.1 - 0.12 12.1 0.4 0.17 11.5 0.4 1.2 1 0 0 1 1 1 0 Cyclodipeptide synthase SHE3 PF17078.5 CRK30869.1 - 0.23 11.1 2.8 0.35 10.5 2.8 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 UPF0242 PF06785.11 CRK30869.1 - 0.3 11.1 1.1 0.44 10.6 1.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus HalX PF08663.10 CRK30869.1 - 0.94 9.8 4.4 0.54 10.6 1.9 2.0 2 1 1 3 3 2 0 HalX domain zf-H2C2_2 PF13465.6 CRK30869.1 - 6.9 7.3 15.7 20 5.8 0.0 3.8 3 1 0 3 3 3 0 Zinc-finger double domain Filament PF00038.21 CRK30870.1 - 0.00023 20.9 13.2 0.00023 20.9 13.2 5.8 3 1 2 5 5 5 1 Intermediate filament protein ATG16 PF08614.11 CRK30870.1 - 0.0016 18.7 21.7 0.0016 18.7 21.7 5.0 2 2 2 4 4 3 1 Autophagy protein 16 (ATG16) TSC22 PF01166.18 CRK30870.1 - 0.0036 17.6 17.1 0.017 15.5 0.3 5.4 6 0 0 6 6 6 2 TSC-22/dip/bun family KASH_CCD PF14662.6 CRK30870.1 - 0.008 16.0 5.9 0.008 16.0 5.9 5.2 4 2 0 5 5 5 2 Coiled-coil region of CCDC155 or KASH NPV_P10 PF05531.12 CRK30870.1 - 0.025 15.1 0.5 3 8.4 0.0 3.8 3 2 0 4 4 3 0 Nucleopolyhedrovirus P10 protein HALZ PF02183.18 CRK30870.1 - 0.13 12.5 0.2 0.13 12.5 0.2 5.3 6 0 0 6 6 6 0 Homeobox associated leucine zipper Scaffolding_pro PF11418.8 CRK30870.1 - 0.2 12.2 0.1 0.2 12.2 0.1 2.8 3 1 0 3 3 2 0 Phi29 scaffolding protein FlaC_arch PF05377.11 CRK30870.1 - 1.2 9.6 24.5 1.5 9.3 0.6 6.5 6 1 0 6 6 6 0 Flagella accessory protein C (FlaC) Shugoshin_N PF07558.11 CRK30870.1 - 3.3 7.7 17.0 3.5 7.6 0.2 5.3 5 0 0 5 5 5 0 Shugoshin N-terminal coiled-coil region DUF5631 PF18645.1 CRK30870.1 - 5.6 7.4 6.0 2 8.8 0.5 2.8 2 1 2 4 4 4 0 Family of unknown function (DUF5631) NYD-SP28_assoc PF14775.6 CRK30870.1 - 6.3 7.0 10.8 26 5.0 0.6 4.1 3 0 0 3 3 3 0 Sperm tail C-terminal domain DUF5308 PF17233.2 CRK30871.1 - 2.8e-57 193.5 23.2 9.9e-57 191.8 23.2 1.8 1 1 0 1 1 1 1 Family of unknown function (DUF5308) Transketolase_N PF00456.21 CRK30872.1 - 1.1e-155 517.7 0.0 1.6e-155 517.2 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 CRK30872.1 - 1.2e-44 152.1 0.0 1.9e-44 151.4 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 CRK30872.1 - 7.8e-14 51.6 0.0 1.5e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 CRK30872.1 - 0.0061 15.8 0.0 0.0098 15.1 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Syja_N PF02383.18 CRK30873.1 - 7.1e-94 314.7 0.0 9.8e-94 314.2 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 CRK30873.1 - 8e-40 135.1 0.0 1.7e-39 134.1 0.0 1.6 1 0 0 1 1 1 1 Inositol phosphatase FA_hydroxylase PF04116.13 CRK30873.1 - 3.7e-23 82.3 21.9 7.5e-23 81.3 21.9 1.5 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily Ribosomal_L7Ae PF01248.26 CRK30874.1 - 2e-24 85.1 0.2 2.6e-24 84.8 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 CRK30874.1 - 0.00047 20.2 0.0 0.0007 19.7 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.6 CRK30874.1 - 0.00064 19.6 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 PELOTA RNA binding domain ATP-synt_C PF00137.21 CRK30876.1 - 2.2e-34 117.6 34.8 9.6e-22 77.1 15.6 2.1 2 0 0 2 2 2 2 ATP synthase subunit C ERG4_ERG24 PF01222.17 CRK30877.1 - 2.2e-137 458.3 18.0 2.8e-137 458.0 18.0 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Translin PF01997.16 CRK30878.1 - 1.4e-47 162.3 0.0 1.7e-47 162.1 0.0 1.0 1 0 0 1 1 1 1 Translin family Fusion_F0 PF13044.6 CRK30878.1 - 0.055 12.1 0.0 0.079 11.6 0.0 1.1 1 0 0 1 1 1 0 Fusion glycoprotein F0, Isavirus Pkinase PF00069.25 CRK30879.1 - 2.7e-71 240.0 0.0 5.7e-71 239.0 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK30879.1 - 5.4e-49 166.8 0.0 9.1e-49 166.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CRK30879.1 - 1.7e-05 23.8 0.0 3.5e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CRK30879.1 - 0.0097 15.3 0.0 0.086 12.1 0.1 2.0 2 0 0 2 2 2 1 Kinase-like DUF218 PF02698.17 CRK30881.1 - 1.7e-05 24.9 0.0 2.4e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 DUF218 domain ICE2 PF08426.10 CRK30882.1 - 3.1e-154 514.0 4.9 3.8e-154 513.7 4.9 1.1 1 0 0 1 1 1 1 ICE2 Peptidase_S9 PF00326.21 CRK30882.1 - 0.031 13.8 0.0 0.47 9.9 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 CRK30882.1 - 0.036 13.3 0.1 5.3 6.2 0.0 2.3 2 0 0 2 2 2 0 Serine aminopeptidase, S33 ABC2_membrane_5 PF13346.6 CRK30882.1 - 0.59 9.6 11.0 0.12 12.0 2.2 2.5 2 0 0 2 2 2 0 ABC-2 family transporter protein FA_desaturase PF00487.24 CRK30883.1 - 1.9e-21 77.1 11.6 2.8e-11 43.7 4.6 2.2 1 1 1 2 2 2 2 Fatty acid desaturase Lipid_DES PF08557.10 CRK30883.1 - 3.6e-18 64.7 0.5 6.1e-18 64.0 0.5 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Motile_Sperm PF00635.26 CRK30884.1 - 1.2e-24 86.3 0.3 2.3e-24 85.3 0.3 1.6 1 1 0 1 1 1 1 MSP (Major sperm protein) domain ASH PF15780.5 CRK30884.1 - 0.0005 20.2 0.2 0.0019 18.4 0.2 2.0 1 1 1 2 2 2 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin FixG_C PF11614.8 CRK30884.1 - 0.0043 17.3 0.5 0.023 14.9 0.0 2.1 2 0 0 2 2 2 1 IG-like fold at C-terminal of FixG, putative oxidoreductase UBX PF00789.20 CRK30885.1 - 3e-07 30.5 0.1 7.6e-07 29.2 0.1 1.7 1 0 0 1 1 1 1 UBX domain UBA PF00627.31 CRK30885.1 - 7e-05 22.6 0.0 0.00026 20.8 0.0 2.0 1 0 0 1 1 1 1 UBA/TS-N domain FapA PF03961.13 CRK30885.1 - 0.7 8.4 13.4 1.1 7.8 13.4 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A UPF0242 PF06785.11 CRK30885.1 - 1.9 8.6 19.4 3.4 7.7 19.4 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus GAGA_bind PF06217.12 CRK30885.1 - 6.5 6.9 14.3 8.6 6.6 14.3 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Presenilin PF01080.17 CRK30885.1 - 6.7 5.4 10.4 7.7 5.2 10.4 1.3 1 0 0 1 1 1 0 Presenilin Ribosomal_60s PF00428.19 CRK30886.1 - 1.9e-27 95.7 9.6 2.3e-27 95.4 9.6 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Phage_holin_6_1 PF09682.10 CRK30886.1 - 0.1 13.0 0.3 0.19 12.2 0.3 1.4 1 0 0 1 1 1 0 Bacteriophage holin of superfamily 6 (Holin_LLH) DUF2408 PF10303.9 CRK30887.1 - 4.7e-37 127.6 11.8 1.2e-22 80.9 0.7 4.8 3 2 1 4 4 4 4 Protein of unknown function (DUF2408) STN1_2 PF09170.10 CRK30887.1 - 0.0031 17.7 4.5 3.5 7.8 0.4 3.3 2 1 1 3 3 3 2 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 TRPM_tetra PF16519.5 CRK30887.1 - 0.12 12.5 1.0 3.3 7.9 0.1 2.8 2 0 0 2 2 2 0 Tetramerisation domain of TRPM Noelin-1 PF12308.8 CRK30887.1 - 2.7 8.0 5.4 2.7 8.0 0.3 3.2 3 0 0 3 3 3 0 Neurogenesis glycoprotein Snapin_Pallidin PF14712.6 CRK30887.1 - 4.2 7.9 10.0 1.1 9.7 0.4 4.4 3 1 1 4 4 4 0 Snapin/Pallidin YCII PF03795.14 CRK30888.1 - 8.2e-05 22.9 0.0 0.00015 22.1 0.0 1.5 1 1 0 1 1 1 1 YCII-related domain Mito_carr PF00153.27 CRK30889.1 - 7.8e-60 198.8 3.1 1.5e-21 76.1 0.0 3.8 2 2 1 3 3 3 3 Mitochondrial carrier protein AhpC-TSA PF00578.21 CRK30889.1 - 1.3e-23 83.2 0.0 2.6e-23 82.3 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CRK30889.1 - 1.8e-13 50.4 0.0 3.4e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 CRK30889.1 - 0.039 14.1 0.0 0.11 12.6 0.0 1.7 1 1 0 1 1 1 0 AhpC/TSA antioxidant enzyme UCR_14kD PF02271.16 CRK30892.1 - 5.5e-43 145.0 0.3 6.8e-43 144.7 0.3 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Anp1 PF03452.14 CRK30893.1 - 1.4e-96 323.0 0.0 1.9e-96 322.5 0.0 1.2 1 0 0 1 1 1 1 Anp1 Recep_L_domain PF01030.24 CRK30894.1 - 2.6e-05 24.3 0.8 0.65 10.1 0.0 4.1 2 2 1 3 3 3 3 Receptor L domain Ecm33 PF12454.8 CRK30894.1 - 0.00055 20.0 3.0 0.0017 18.4 3.0 1.8 1 0 0 1 1 1 1 GPI-anchored cell wall organization protein G-patch PF01585.23 CRK30895.1 - 1.1e-12 47.6 0.2 2.9e-12 46.3 0.2 1.7 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 CRK30895.1 - 0.0086 15.9 0.1 0.019 14.8 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AMP-binding PF00501.28 CRK30896.1 - 2.1e-64 217.7 0.0 2.3e-64 217.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme GH3 PF03321.13 CRK30896.1 - 0.00092 18.2 0.0 0.0014 17.6 0.0 1.2 1 0 0 1 1 1 1 GH3 auxin-responsive promoter Bac_rhamnosid_N PF08531.10 CRK30899.1 - 8.3e-42 142.9 0.8 8.3e-22 77.8 0.4 2.2 2 0 0 2 2 2 2 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid PF05592.11 CRK30899.1 - 3.8e-19 68.6 0.0 7.1e-19 67.7 0.0 1.5 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Bac_rhamnosid6H PF17389.2 CRK30899.1 - 2.7e-10 40.0 0.0 6.9e-10 38.7 0.0 1.6 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain DUF3344 PF11824.8 CRK30899.1 - 0.03 13.9 0.0 0.089 12.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3344) Abhydrolase_6 PF12697.7 CRK30900.1 - 1.2e-12 48.9 11.8 2e-12 48.2 11.8 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CRK30900.1 - 6.5e-05 22.7 0.0 0.00043 20.0 0.0 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CRK30900.1 - 0.00044 19.6 0.0 0.00073 18.9 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 CRK30900.1 - 0.14 11.0 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Gryzun PF07919.12 CRK30901.1 - 7.7e-229 761.4 0.0 1e-228 760.9 0.0 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.8 CRK30901.1 - 8.7e-87 291.0 2.1 1.1e-81 274.3 3.4 2.2 2 0 0 2 2 2 2 Foie gras liver health family 1 Gryzun-like PF12742.7 CRK30901.1 - 4.2e-05 23.5 0.0 7.9e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking PEMT PF04191.13 CRK30902.1 - 2.5e-32 111.4 2.2 4.4e-32 110.6 2.2 1.4 1 0 0 1 1 1 1 Phospholipid methyltransferase COesterase PF00135.28 CRK30902.1 - 0.024 13.5 0.1 0.033 13.1 0.1 1.1 1 0 0 1 1 1 0 Carboxylesterase family DUF202 PF02656.15 CRK30902.1 - 0.16 12.4 1.5 1.5 9.3 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF202) FGGY_N PF00370.21 CRK30903.1 - 2e-46 158.5 0.2 2.5e-46 158.2 0.2 1.0 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain NTP_transferase PF00483.23 CRK30904.1 - 9e-24 84.4 0.0 9.8e-24 84.3 0.0 1.0 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 CRK30904.1 - 2.7e-10 40.8 0.0 2.9e-10 40.7 0.0 1.0 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 CRK30904.1 - 0.0039 17.0 0.0 0.0044 16.8 0.0 1.1 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CTP_transf_3 PF02348.19 CRK30904.1 - 0.018 15.0 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 Cytidylyltransferase zf-AN1 PF01428.16 CRK30906.1 - 3.2e-25 88.0 25.0 1.7e-12 47.3 6.8 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger Remorin_C PF03763.13 CRK30906.1 - 0.011 15.6 0.2 0.011 15.6 0.2 1.6 2 0 0 2 2 2 0 Remorin, C-terminal region IBR PF01485.21 CRK30906.1 - 0.013 15.7 4.0 0.013 15.7 4.0 2.7 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain Transp_Tc5_C PF04236.15 CRK30906.1 - 0.077 13.4 15.2 1.2 9.5 6.2 2.3 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain DpnI PF06044.12 CRK30906.1 - 0.44 10.2 2.3 2.9 7.5 0.5 2.2 2 0 0 2 2 2 0 Dam-replacing family FA_desaturase PF00487.24 CRK30909.1 - 1e-15 58.3 14.0 1.3e-15 58.0 14.0 1.1 1 0 0 1 1 1 1 Fatty acid desaturase DAO PF01266.24 CRK30912.1 - 5.5e-31 108.4 0.0 6.6e-31 108.2 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CRK30912.1 - 0.00073 18.7 0.0 0.0009 18.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain WavE PF07507.11 CRK30913.1 - 0.047 12.9 0.0 0.057 12.6 0.0 1.0 1 0 0 1 1 1 0 WavE lipopolysaccharide synthesis Cation_ATPase PF13246.6 CRK30914.1 - 6e-12 45.5 0.0 9.9e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CRK30914.1 - 2.4e-05 24.7 0.0 5e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Rer1 PF03248.13 CRK30915.1 - 3.3e-61 206.0 6.2 3.8e-61 205.8 6.2 1.0 1 0 0 1 1 1 1 Rer1 family DcrB PF08786.11 CRK30916.1 - 0.061 13.4 0.3 0.081 13.0 0.3 1.3 1 1 0 1 1 1 0 DcrB Spc24 PF08286.11 CRK30916.1 - 0.079 13.2 0.1 0.18 12.1 0.0 1.6 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF1640 PF07798.11 CRK30916.1 - 0.088 12.8 1.8 0.14 12.2 1.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) Syntaxin PF00804.25 CRK30916.1 - 0.25 11.0 3.7 0.088 12.5 1.3 1.4 2 0 0 2 2 2 0 Syntaxin HALZ PF02183.18 CRK30916.1 - 0.48 10.7 3.1 1.8 8.9 0.7 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper Cep57_CLD_2 PF14197.6 CRK30916.1 - 1.8 8.7 8.9 1.3 9.2 4.4 2.2 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 WD40 PF00400.32 CRK30917.1 - 1.7e-16 60.3 2.1 3.2e-08 34.1 0.5 2.6 2 1 0 2 2 2 2 WD domain, G-beta repeat Nup160 PF11715.8 CRK30917.1 - 0.093 11.4 0.0 0.85 8.2 0.0 1.9 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Glycos_transf_1 PF00534.20 CRK30918.1 - 2.7e-20 72.6 0.0 1.5e-18 66.9 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CRK30918.1 - 4e-06 27.3 0.1 1.2e-05 25.7 0.1 1.8 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CRK30918.1 - 0.00032 20.8 0.0 0.00055 20.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 PrpR_N PF06506.11 CRK30918.1 - 0.11 12.1 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 Propionate catabolism activator Ammonium_transp PF00909.21 CRK30919.1 - 2.6e-72 243.7 20.4 2.9e-72 243.6 20.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF441 PF04284.13 CRK30919.1 - 0.05 13.6 0.8 0.11 12.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF441) MMR_HSR1 PF01926.23 CRK30921.1 - 5.4e-24 84.5 0.0 7.6e-24 84.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CRK30921.1 - 1.7e-08 34.2 0.0 9e-08 31.8 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP1_OBG PF01018.22 CRK30921.1 - 2.2e-07 30.6 0.0 3.5e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 GTP1/OBG ABC_tran PF00005.27 CRK30921.1 - 0.01 16.4 0.0 0.013 16.0 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 CRK30921.1 - 0.025 15.1 0.0 0.041 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 CRK30921.1 - 0.044 13.2 0.0 0.067 12.6 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family Dynamin_N PF00350.23 CRK30921.1 - 0.087 12.9 0.0 2.9 7.9 0.0 2.1 1 1 1 2 2 2 0 Dynamin family MeaB PF03308.16 CRK30921.1 - 0.094 11.7 0.0 0.18 10.7 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Cation_ATPase_C PF00689.21 CRK30923.1 - 5.4e-45 153.3 7.8 8.1e-45 152.8 7.8 1.3 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus DUF4870 PF09685.10 CRK30923.1 - 0.2 11.8 0.3 0.2 11.8 0.3 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4870) APS_kinase PF01583.20 CRK30924.1 - 4.1e-52 176.3 0.0 4.6e-52 176.1 0.0 1.0 1 0 0 1 1 1 1 Adenylylsulphate kinase TTL PF03133.15 CRK30925.1 - 1.1e-08 34.6 0.0 1.3e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SIR2 PF02146.17 CRK30926.1 - 4.8e-13 49.4 0.0 6.4e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 Sir2 family Aminotran_4 PF01063.19 CRK30927.1 - 4.5e-35 121.5 0.0 5.2e-35 121.3 0.0 1.0 1 0 0 1 1 1 1 Amino-transferase class IV DUF2841 PF11001.8 CRK30929.1 - 0.1 12.6 2.1 0.16 12.0 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2841) SMC_N PF02463.19 CRK30940.1 - 2.9e-08 33.4 2.1 3.1e-07 30.1 1.5 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain Stathmin PF00836.19 CRK30940.1 - 0.38 10.7 8.2 0.55 10.2 8.2 1.3 1 0 0 1 1 1 0 Stathmin family AAA_23 PF13476.6 CRK30940.1 - 3.4 8.1 12.8 5.6 7.4 12.8 1.3 1 1 0 1 1 1 0 AAA domain LisH PF08513.11 CRK30950.1 - 2.1e-08 33.8 0.1 3.3e-08 33.2 0.1 1.3 1 0 0 1 1 1 1 LisH Septin PF00735.18 CRK30957.1 - 5.9e-19 68.4 0.0 7.1e-19 68.2 0.0 1.1 1 0 0 1 1 1 1 Septin Ank_2 PF12796.7 CRK30960.1 - 1.7e-11 44.5 0.0 2.1e-05 25.0 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CRK30960.1 - 4.1e-09 36.8 0.0 0.0016 19.0 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 CRK30960.1 - 2.4e-07 30.9 0.5 0.029 14.8 0.1 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 CRK30960.1 - 6.7e-06 26.3 0.1 0.023 15.0 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CRK30960.1 - 8.1e-06 25.8 0.1 0.54 11.0 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Pyr_redox_2 PF07992.14 CRK30960.1 - 0.027 13.7 0.0 0.056 12.7 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF4682 PF15733.5 CRK30966.1 - 0.0015 19.1 4.0 0.25 11.9 0.5 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4682) Utp14 PF04615.13 CRK30975.1 - 7.4e-59 200.1 47.7 8.2e-59 199.9 47.7 1.0 1 0 0 1 1 1 1 Utp14 protein MPP6 PF10175.9 CRK30975.1 - 0.067 13.7 2.8 0.067 13.7 2.8 3.5 2 1 0 2 2 2 0 M-phase phosphoprotein 6 Glyco_transf_22 PF03901.17 CRK30978.1 - 1.3e-27 97.1 6.7 1.3e-27 97.1 6.7 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PMT_2 PF13231.6 CRK30978.1 - 0.0011 19.3 3.8 0.0015 18.7 3.7 1.4 1 1 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase NOA36 PF06524.12 CRK30980.1 - 0.0032 16.9 1.2 0.004 16.5 1.2 1.1 1 0 0 1 1 1 1 NOA36 protein zinc_ribbon_9 PF14369.6 CRK30980.1 - 0.34 11.2 3.0 0.6 10.4 1.8 2.1 2 0 0 2 2 2 0 zinc-ribbon DIL PF01843.19 CRK30984.1 - 1.1e-21 77.0 0.2 1.5e-21 76.6 0.2 1.2 1 0 0 1 1 1 1 DIL domain FGF-BP1 PF06473.12 CRK30984.1 - 0.033 14.0 3.1 0.049 13.5 3.1 1.2 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) VPS13 PF16908.5 CRK30984.1 - 0.16 11.7 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Vacuolar sorting-associated protein 13, N-terminal CCDC53 PF10152.9 CRK30984.1 - 0.36 11.2 4.9 0.78 10.1 4.9 1.5 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Herpes_DNAp_acc PF04929.12 CRK30984.1 - 4.6 6.1 5.0 6.5 5.6 5.0 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor MMR_HSR1 PF01926.23 CRK30987.1 - 8.2e-11 42.0 0.0 1.4e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CRK30987.1 - 0.0039 17.1 0.6 0.032 14.2 0.1 2.2 2 1 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 CRK30987.1 - 0.0071 16.7 0.1 0.011 16.1 0.1 1.3 1 0 0 1 1 1 1 AAA ATPase domain FeoB_N PF02421.18 CRK30987.1 - 0.0074 15.8 0.3 0.013 15.0 0.0 1.5 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 CRK30987.1 - 0.043 12.8 0.1 0.069 12.1 0.1 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 CRK30987.1 - 0.047 13.7 0.0 1.3 9.0 0.0 2.2 2 0 0 2 2 2 0 Dynamin family AAA_18 PF13238.6 CRK30987.1 - 0.053 14.1 0.0 0.1 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 CRK30987.1 - 0.066 12.7 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family Roc PF08477.13 CRK30987.1 - 0.1 12.8 0.0 0.22 11.8 0.0 1.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase B2 PF11473.8 CRK30987.1 - 0.17 11.7 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 RNA binding protein B2 DAP3 PF10236.9 CRK30987.1 - 0.24 10.5 0.1 0.35 10.0 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Hydantoinase_B PF02538.14 CRK30989.1 - 1.7e-215 716.3 3.1 2.6e-215 715.7 3.1 1.3 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 CRK30989.1 - 6.6e-97 324.3 0.6 5.4e-95 318.0 0.1 2.8 2 1 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 CRK30989.1 - 2.9e-57 193.2 0.0 6.2e-55 185.7 0.0 2.4 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region DUF1445 PF07286.12 CRK30991.1 - 1.1e-60 203.7 0.0 1.6e-60 203.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1445) MFS_1 PF07690.16 CRK30992.1 - 5.2e-25 88.1 38.2 4.6e-23 81.7 20.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK30992.1 - 0.00028 19.9 21.7 0.002 17.0 8.3 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 CRK30992.1 - 0.0015 17.9 9.9 0.0015 17.9 9.9 2.1 1 1 1 2 2 2 1 Uncharacterised MFS-type transporter YbfB Fungal_trans PF04082.18 CRK30994.1 - 2e-29 102.5 0.6 3e-29 101.9 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK30994.1 - 3.3e-05 23.9 4.7 6.1e-05 23.0 4.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Arf PF00025.21 CRK30996.1 - 1.8e-36 125.2 0.0 7.2e-22 77.7 0.0 2.0 1 1 1 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 CRK30996.1 - 0.0018 18.5 0.0 1.1 9.4 0.0 2.1 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 CRK30996.1 - 0.0037 16.5 0.2 0.54 9.4 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 CRK30996.1 - 0.0079 15.8 0.0 0.44 10.1 0.0 2.1 1 1 1 2 2 2 1 Ras family MMR_HSR1 PF01926.23 CRK30996.1 - 0.0099 15.9 0.0 0.17 12.0 0.0 2.0 1 1 1 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CRK30996.1 - 0.057 13.0 0.0 8.1 5.9 0.0 2.1 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain SRPRB PF09439.10 CRK30996.1 - 0.096 12.1 0.0 0.2 11.1 0.0 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit YqzM PF14141.6 CRK30996.1 - 2.6 8.2 6.8 0.38 10.8 2.5 1.7 2 0 0 2 2 2 0 YqzM-like protein HCO3_cotransp PF00955.21 CRK30999.1 - 5.1e-72 243.3 6.0 4.5e-38 131.3 0.0 2.1 1 1 1 2 2 2 2 HCO3- transporter family DUF3341 PF11821.8 CRK30999.1 - 0.11 12.1 0.1 0.11 12.1 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3341) adh_short PF00106.25 CRK31001.1 - 6.9e-10 38.7 0.0 9.9e-10 38.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK31001.1 - 0.00012 21.7 0.0 0.0011 18.5 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Zn_clus PF00172.18 CRK31003.1 - 0.0002 21.4 3.7 0.00041 20.4 3.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ARF7EP_C PF14949.6 CRK31003.1 - 0.9 10.2 7.8 0.17 12.5 2.8 2.0 2 0 0 2 2 2 0 ARF7 effector protein C-terminus GTP_EFTU PF00009.27 CRK31009.1 - 6.7e-30 104.1 0.7 8e-30 103.8 0.7 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CRK31009.1 - 0.00015 21.8 0.0 0.00024 21.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Hydrolase_3 PF08282.12 CRK31015.1 - 0.0037 17.0 0.7 0.0059 16.4 0.1 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cu-oxidase_2 PF07731.14 CRK31020.1 - 5.9e-40 136.2 2.4 7.3e-40 135.9 2.4 1.1 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 CRK31020.1 - 0.054 13.5 0.1 0.19 11.8 0.0 1.8 2 0 0 2 2 2 0 Multicopper oxidase DUF5060 PF16586.5 CRK31020.1 - 0.1 13.0 0.0 0.26 11.7 0.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF5060) Cupredoxin_1 PF13473.6 CRK31020.1 - 0.21 11.7 0.0 2.2 8.5 0.0 2.1 2 0 0 2 2 2 0 Cupredoxin-like domain HSP70 PF00012.20 CRK31024.1 - 8.3e-75 252.1 0.0 9.2e-75 252.0 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CRK31024.1 - 7.4e-09 34.9 0.0 1.1e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 MreB/Mbl protein FtsA PF14450.6 CRK31024.1 - 0.11 13.0 0.0 1.7 9.1 0.0 2.3 2 0 0 2 2 2 0 Cell division protein FtsA MpPF1 PF07668.11 CRK31024.1 - 0.12 11.7 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 M penetrans paralogue family 1 Chitin_bind_1 PF00187.19 CRK31029.1 - 7.3e-07 29.6 9.3 7.3e-07 29.6 9.3 3.1 2 2 0 2 2 2 1 Chitin recognition protein LysM PF01476.20 CRK31029.1 - 1.8e-05 24.7 0.0 5.5e-05 23.2 0.0 1.9 1 0 0 1 1 1 1 LysM domain Helicase_C PF00271.31 CRK31033.1 - 2.2e-28 98.8 0.0 4.1e-28 97.9 0.0 1.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RimK PF08443.11 CRK31037.1 - 9.2e-09 35.2 0.0 1.3e-08 34.7 0.0 1.1 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 CRK31037.1 - 0.019 15.0 0.0 0.031 14.3 0.0 1.4 1 1 0 1 1 1 0 ATP-grasp domain Choline_kinase PF01633.20 CRK31050.1 - 5.7e-22 78.4 0.0 1.1e-20 74.1 0.0 2.3 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 CRK31050.1 - 2.3e-07 31.0 0.1 7.2e-07 29.4 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.11 CRK31050.1 - 0.021 13.7 0.0 0.028 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Ribosomal_L2_C PF03947.18 CRK31058.1 - 6.7e-22 78.0 0.1 1.2e-21 77.2 0.1 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 CRK31058.1 - 1.9e-15 56.6 0.1 3.3e-15 55.8 0.1 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Bac_luciferase PF00296.20 CRK31061.1 - 4.4e-35 121.6 0.1 5.1e-35 121.4 0.1 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase adh_short PF00106.25 CRK31062.1 - 2.5e-34 118.4 0.4 3.3e-34 118.1 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK31062.1 - 3.6e-27 95.4 0.6 4.6e-27 95.1 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK31062.1 - 1.6e-06 28.2 0.8 3.1e-06 27.2 0.8 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 CRK31062.1 - 0.0094 15.9 0.7 0.013 15.4 0.7 1.2 1 0 0 1 1 1 1 NAD(P)H-binding FtsJ PF01728.19 CRK31062.1 - 0.13 12.4 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Mitofilin PF09731.9 CRK31063.1 - 5.4e-96 322.9 8.9 5.9e-96 322.7 8.9 1.0 1 0 0 1 1 1 1 Mitochondrial inner membrane protein DUF4363 PF14276.6 CRK31063.1 - 0.078 13.1 0.0 0.45 10.6 0.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4363) Fungal_trans PF04082.18 CRK31064.1 - 3.5e-13 49.2 0.0 4.6e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK31064.1 - 4.6e-06 26.6 7.5 1.1e-05 25.4 7.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SdpI PF13630.6 CRK31066.1 - 0.07 13.3 0.5 0.07 13.3 0.5 3.2 2 1 1 3 3 3 0 SdpI/YhfL protein family DUF1772 PF08592.11 CRK31066.1 - 0.42 10.9 7.2 3.8 7.8 0.1 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF1772) Pkinase PF00069.25 CRK31067.1 - 1.4e-40 139.4 0.0 1.5e-40 139.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK31067.1 - 1.7e-20 73.4 0.0 2.1e-20 73.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CRK31067.1 - 0.00033 20.7 0.1 0.033 14.1 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CRK31067.1 - 0.0012 17.8 0.0 0.0013 17.7 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 CRK31067.1 - 0.0017 17.5 0.0 0.0027 16.8 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Zip PF02535.22 CRK31068.1 - 1.1e-17 64.3 11.1 1.4e-17 64.0 11.1 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter PTPS_related PF10131.9 CRK31068.1 - 2.3 6.4 8.6 2.5 6.3 8.6 1.1 1 0 0 1 1 1 0 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein PX PF00787.24 CRK31069.1 - 0.00087 19.3 0.2 0.0014 18.6 0.2 1.3 1 0 0 1 1 1 1 PX domain Nexin_C PF08628.12 CRK31069.1 - 0.012 16.2 0.4 0.09 13.4 0.1 2.1 2 0 0 2 2 2 0 Sorting nexin C terminal Ammonium_transp PF00909.21 CRK31070.1 - 5.7e-61 206.4 20.7 6.4e-61 206.2 20.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF2406 PF10295.9 CRK31071.1 - 1.9e-28 99.0 0.4 2.2e-28 98.7 0.4 1.1 1 0 0 1 1 1 1 Uncharacterised protein (DUF2406) Flavodoxin_1 PF00258.25 CRK31072.1 - 1.1e-29 103.5 0.9 1.5e-29 103.1 0.9 1.2 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 CRK31072.1 - 0.00076 19.7 0.0 0.0033 17.7 0.0 2.2 2 1 0 2 2 2 1 Flavodoxin domain DUF5603 PF18231.1 CRK31072.1 - 0.11 12.8 0.0 14 6.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5603) Oxysterol_BP PF01237.18 CRK31073.1 - 7e-22 77.8 0.0 9.2e-22 77.4 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein DBI_PRT PF02277.17 CRK31073.1 - 0.18 11.0 0.0 0.42 9.8 0.0 1.5 2 0 0 2 2 2 0 Phosphoribosyltransferase AA_permease_2 PF13520.6 CRK31074.1 - 1.2e-31 110.0 16.2 1.4e-31 109.8 16.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CRK31074.1 - 4e-17 62.0 14.4 4.7e-17 61.7 14.4 1.1 1 0 0 1 1 1 1 Amino acid permease Phage_holin_4_1 PF05105.12 CRK31074.1 - 0.022 14.9 1.5 0.022 14.9 1.5 2.1 2 1 0 2 2 2 0 Bacteriophage holin family Capsule_synth PF05159.14 CRK31075.1 - 0.11 12.0 0.1 0.13 11.7 0.1 1.1 1 0 0 1 1 1 0 Capsule polysaccharide biosynthesis protein Cation_efflux PF01545.21 CRK31079.1 - 1.2e-14 54.5 0.5 1.7e-14 54.1 0.5 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 CRK31079.1 - 0.018 15.1 0.4 0.03 14.4 0.1 1.5 2 0 0 2 2 2 0 Dimerisation domain of Zinc Transporter BPD_transp_2 PF02653.16 CRK31079.1 - 0.032 13.4 0.8 0.042 13.0 0.8 1.1 1 0 0 1 1 1 0 Branched-chain amino acid transport system / permease component SMC_hinge PF06470.13 CRK31082.1 - 3.2e-29 101.6 0.0 5.3e-29 100.9 0.0 1.4 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain Cyclin_N PF00134.23 CRK31089.1 - 3e-10 39.9 0.2 4.5e-10 39.3 0.2 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Fig1 PF12351.8 CRK31093.1 - 4.6e-26 91.9 3.8 5.5e-26 91.6 3.8 1.0 1 0 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.12 CRK31093.1 - 3.5 7.2 8.6 4.3 6.9 8.6 1.1 1 0 0 1 1 1 0 SUR7/PalI family PrgI PF12666.7 CRK31093.1 - 5.9 7.7 11.0 0.99 10.2 2.4 2.0 1 1 1 2 2 2 0 PrgI family protein PBP1_TM PF14812.6 CRK31100.1 - 0.017 15.5 8.5 0.017 15.5 8.5 1.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.6 CRK31100.1 - 0.14 11.8 2.1 0.25 11.0 2.1 1.4 1 0 0 1 1 1 0 FAM176 family CENP-B_dimeris PF09026.10 CRK31100.1 - 0.3 11.5 8.5 0.6 10.5 8.5 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain CDC45 PF02724.14 CRK31100.1 - 1.2 7.3 4.2 1.5 7.0 4.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 CRK31100.1 - 4 5.4 7.3 5.6 4.9 7.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 CRK31100.1 - 6.4 6.0 10.2 8.7 5.6 10.2 1.1 1 0 0 1 1 1 0 NOA36 protein Transket_pyr PF02779.24 CRK31102.1 - 2.6e-58 196.6 0.0 3.1e-58 196.4 0.0 1.0 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain PAS_4 PF08448.10 CRK31103.1 - 8.3e-05 22.8 0.0 0.00015 22.0 0.0 1.4 1 1 0 1 1 1 1 PAS fold HisG PF01634.18 CRK31104.1 - 3.1e-116 384.8 0.0 1.3e-53 181.2 0.0 3.3 3 0 0 3 3 3 3 ATP phosphoribosyltransferase HisG_C PF08029.11 CRK31104.1 - 5.5e-27 93.7 0.2 1.3e-26 92.6 0.2 1.7 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.11 CRK31104.1 - 9.8e-06 25.7 0.0 45 3.9 0.0 6.3 6 2 0 6 6 6 0 NMT1/THI5 like DUF3837 PF12939.7 CRK31104.1 - 0.0049 17.2 0.0 3.1 8.2 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3837) MFS_2 PF13347.6 CRK31106.1 - 1.7e-12 46.6 13.9 1.7e-12 46.6 13.9 2.5 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.7 CRK31106.1 - 0.00018 20.5 3.3 0.00055 18.9 3.3 2.0 1 1 0 1 1 1 1 MFS_1 like family PUCC PF03209.15 CRK31106.1 - 0.0005 19.2 6.5 0.00099 18.2 6.5 1.4 1 0 0 1 1 1 1 PUCC protein Serpentine_r_xa PF03383.15 CRK31106.1 - 1.1 9.2 3.3 8.4 6.4 0.1 2.8 3 0 0 3 3 3 0 Caenorhabditis serpentine receptor-like protein, class xa Pkr1 PF08636.10 CRK31107.1 - 1.5e-31 108.4 4.9 1.9e-31 108.0 4.9 1.1 1 0 0 1 1 1 1 ER protein Pkr1 Auxin_repressed PF05564.12 CRK31107.1 - 0.022 15.4 1.5 5.1 7.8 0.0 2.4 2 0 0 2 2 2 0 Dormancy/auxin associated protein BUD22 PF09073.10 CRK31108.1 - 5.1 6.3 10.5 7.3 5.8 10.5 1.1 1 0 0 1 1 1 0 BUD22 Cpn60_TCP1 PF00118.24 CRK31112.1 - 4.3e-57 193.9 0.2 4.7e-57 193.7 0.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ORC2 PF04084.14 CRK31113.1 - 7.5e-67 225.6 0.0 8.3e-67 225.4 0.0 1.0 1 0 0 1 1 1 1 Origin recognition complex subunit 2 NTP_transf_3 PF12804.7 CRK31113.1 - 0.011 16.1 0.1 0.016 15.6 0.1 1.2 1 0 0 1 1 1 0 MobA-like NTP transferase domain MKT1_C PF12246.8 CRK31114.1 - 3.7e-43 147.5 0.0 4.4e-43 147.2 0.0 1.1 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication adh_short PF00106.25 CRK31115.1 - 3.1e-27 95.3 0.0 4.1e-27 94.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK31115.1 - 3.5e-20 72.6 0.0 4.5e-20 72.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK31115.1 - 9.9e-11 41.9 1.2 5.9e-10 39.3 1.2 1.9 1 1 0 1 1 1 1 KR domain Crp PF00325.20 CRK31115.1 - 0.014 15.1 0.2 0.026 14.2 0.2 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family UIM PF02809.20 CRK31116.1 - 0.004 17.0 1.1 0.014 15.3 1.1 2.0 1 0 0 1 1 1 1 Ubiquitin interaction motif DUF243 PF03103.17 CRK31116.1 - 0.078 13.3 0.2 0.078 13.3 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF243) GPHR_N PF12537.8 CRK31117.1 - 3.5e-23 81.5 0.0 5.6e-23 80.8 0.0 1.3 1 0 0 1 1 1 1 The Golgi pH Regulator (GPHR) Family N-terminal Serglycin PF04360.12 CRK31117.1 - 0.036 14.0 0.7 0.061 13.3 0.7 1.3 1 0 0 1 1 1 0 Serglycin DUF2198 PF09964.9 CRK31117.1 - 0.31 11.2 4.3 7.1 6.8 2.1 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2198) FtsJ PF01728.19 CRK31118.1 - 3.9e-44 150.9 0.0 4.7e-44 150.6 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase UDPGP PF01704.18 CRK31119.1 - 7.8e-49 166.4 0.0 1e-48 166.0 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase ING PF12998.7 CRK31119.1 - 3.2e-09 37.3 0.1 4.7e-09 36.8 0.1 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding FolB PF02152.18 CRK31120.1 - 6.5e-20 71.7 0.1 4.3e-18 65.9 0.1 2.3 2 1 0 2 2 2 2 Dihydroneopterin aldolase ERAP1_C PF11838.8 CRK31122.1 - 9.7e-36 123.9 0.1 1.6e-35 123.2 0.1 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 CRK31122.1 - 1.8e-11 44.0 0.0 2.9e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain LSM PF01423.22 CRK31123.1 - 0.18 11.5 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 LSM domain DUF3405 PF11885.8 CRK31124.1 - 2e-34 119.1 0.0 3e-34 118.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) DUF2236 PF09995.9 CRK31125.1 - 5.8e-22 79.0 1.5 5.8e-22 79.0 1.5 2.0 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2236) FerA PF08165.11 CRK31126.1 - 0.027 14.4 0.2 8.9 6.4 0.0 3.1 3 0 0 3 3 3 0 FerA (NUC095) domain Aminotran_1_2 PF00155.21 CRK31128.1 - 0.0012 18.1 0.0 0.0015 17.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II OTCace PF00185.24 CRK31130.1 - 1.8e-43 148.3 0.0 2.2e-43 148.0 0.0 1.1 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 CRK31130.1 - 2.1e-11 44.0 0.1 3.2e-11 43.5 0.1 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Ribosomal_S9 PF00380.19 CRK31131.1 - 1.5e-23 83.6 0.1 1.6e-23 83.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 mRNA_triPase PF02940.15 CRK31132.1 - 1.2e-34 119.9 0.0 1.4e-34 119.7 0.0 1.0 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain MA3 PF02847.17 CRK31133.1 - 0.063 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 MA3 domain PRMT5 PF05185.16 CRK31134.1 - 2.3e-29 102.4 0.0 3.1e-29 102.1 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_TIM PF17285.2 CRK31134.1 - 1.6e-18 66.9 0.0 2.1e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 PRMT5 TIM barrel domain Nitroreductase PF00881.24 CRK31136.1 - 5.2e-15 55.9 0.0 6.3e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family PS_Dcarbxylase PF02666.15 CRK31137.1 - 3.8e-76 255.1 0.0 1.3e-74 250.1 0.0 2.2 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase ubiquitin PF00240.23 CRK31138.1 - 7.6e-07 28.8 0.0 1.4e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 CRK31138.1 - 2.1e-05 25.0 1.0 5.3e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Rad60-SLD PF11976.8 CRK31138.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like p450 PF00067.22 CRK31139.1 - 6.7e-24 84.5 4.5 1.2e-18 67.1 2.9 3.6 2 1 0 2 2 2 2 Cytochrome P450 HET PF06985.11 CRK31140.1 - 3.1e-09 37.3 0.2 3.1e-09 37.3 0.2 4.4 3 1 1 4 4 4 2 Heterokaryon incompatibility protein (HET) Exo_endo_phos PF03372.23 CRK31141.1 - 2.3e-09 37.2 0.2 2.8e-09 36.8 0.2 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 CRK31141.1 - 0.1 12.4 0.0 0.26 11.1 0.0 1.6 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase adh_short PF00106.25 CRK31142.1 - 5.7e-31 107.5 0.0 7.7e-31 107.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK31142.1 - 4.3e-23 82.1 0.0 5.7e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK31142.1 - 2.5e-08 34.0 0.0 6.1e-06 26.3 0.0 2.2 2 0 0 2 2 2 2 KR domain 3Beta_HSD PF01073.19 CRK31142.1 - 0.045 12.7 0.1 0.063 12.3 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family BIR PF00653.21 CRK31142.1 - 0.12 13.1 0.1 30 5.3 0.1 3.3 3 0 0 3 3 3 0 Inhibitor of Apoptosis domain FMO-like PF00743.19 CRK31143.1 - 9.2e-16 57.3 0.0 6.2e-15 54.6 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 CRK31143.1 - 4.7e-09 36.3 0.0 1.4e-08 34.8 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 CRK31143.1 - 1.1e-08 34.7 0.0 9.2e-07 28.4 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CRK31143.1 - 2.4e-06 27.0 0.0 0.0051 16.1 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CRK31143.1 - 0.0008 18.6 0.1 0.0094 15.1 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 CRK31143.1 - 0.0036 16.6 0.1 3.5 6.8 0.0 2.7 3 0 0 3 3 3 2 Thi4 family NAD_binding_9 PF13454.6 CRK31143.1 - 0.0077 16.2 1.9 0.19 11.7 0.0 3.3 4 0 0 4 4 4 1 FAD-NAD(P)-binding Amino_oxidase PF01593.24 CRK31143.1 - 0.12 11.6 0.0 1.5 8.0 0.0 2.6 2 1 1 3 3 3 0 Flavin containing amine oxidoreductase Fungal_trans PF04082.18 CRK31144.1 - 2.3e-13 49.8 0.5 4e-13 49.0 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK31144.1 - 0.0023 18.0 11.3 0.0041 17.2 11.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 CRK31145.1 - 1.5e-36 126.1 33.7 1.5e-36 126.1 33.7 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MgtC PF02308.16 CRK31145.1 - 0.71 10.2 8.0 5.3 7.4 0.0 4.1 2 1 0 3 3 3 0 MgtC family Lactamase_B PF00753.27 CRK31146.1 - 1.4e-09 38.3 0.2 2.3e-09 37.5 0.2 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CRK31146.1 - 0.0067 16.0 0.0 0.018 14.5 0.0 1.8 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 CRK31146.1 - 0.011 15.6 0.0 0.018 14.9 0.0 1.2 1 0 0 1 1 1 0 Beta-lactamase superfamily domain FMO-like PF00743.19 CRK31147.1 - 5.7e-15 54.7 0.0 9.6e-15 54.0 0.0 1.3 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 CRK31147.1 - 6.9e-15 55.1 0.0 2.9e-14 53.0 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CRK31147.1 - 7.5e-12 45.1 0.0 3.2e-10 39.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CRK31147.1 - 1.8e-09 37.2 0.1 1.6e-07 30.8 0.1 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 CRK31147.1 - 4.3e-06 26.9 0.4 2.5e-05 24.4 0.0 2.5 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CRK31147.1 - 1e-05 25.3 0.0 0.16 11.5 0.0 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CRK31147.1 - 0.00053 19.2 0.0 0.0012 18.1 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain 2-Hacid_dh_C PF02826.19 CRK31147.1 - 0.0026 17.1 0.0 0.0054 16.1 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.14 CRK31147.1 - 0.0036 16.1 0.0 0.88 8.2 0.0 2.4 2 0 0 2 2 2 2 HI0933-like protein Shikimate_DH PF01488.20 CRK31147.1 - 0.0043 17.1 0.0 0.028 14.5 0.0 2.1 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 CRK31147.1 - 0.021 14.1 0.2 0.45 9.7 0.3 2.2 1 1 1 2 2 2 0 FAD binding domain Thi4 PF01946.17 CRK31147.1 - 0.09 12.0 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Abhydrolase_3 PF07859.13 CRK31148.1 - 2.1e-47 161.7 0.0 3.7e-47 160.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 CRK31148.1 - 2.8e-10 39.7 0.0 2e-09 36.9 0.0 2.0 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 CRK31148.1 - 3.9e-05 24.3 0.7 5.7e-05 23.8 0.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 CRK31148.1 - 0.021 14.3 0.3 8.9 5.7 0.0 3.6 3 1 1 4 4 4 0 Prolyl oligopeptidase family adh_short PF00106.25 CRK31149.1 - 2.2e-47 161.1 3.4 2.7e-47 160.7 3.4 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK31149.1 - 5.7e-45 153.7 2.1 6.8e-45 153.4 2.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ecm33 PF12454.8 CRK31149.1 - 0.21 11.7 3.3 6.1 7.1 0.0 2.7 2 0 0 2 2 2 0 GPI-anchored cell wall organization protein ADH_N PF08240.12 CRK31150.1 - 2.6e-21 75.5 1.7 4.3e-21 74.8 1.7 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CRK31150.1 - 4e-13 49.5 0.1 2.1e-12 47.1 0.1 2.2 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CRK31150.1 - 8.7e-11 43.0 0.0 2.4e-10 41.6 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 CRK31150.1 - 0.015 14.7 0.0 0.032 13.6 0.0 1.6 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Exo_endo_phos PF03372.23 CRK31151.1 - 6.2e-16 58.6 0.0 5.9e-15 55.4 0.0 2.1 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.6 CRK31151.1 - 6.6e-08 32.2 4.4 4.1e-05 23.3 0.3 2.4 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 CRK31151.1 - 1.2e-06 28.7 1.4 0.0016 18.8 0.2 3.0 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) Methyltransf_25 PF13649.6 CRK31153.1 - 2e-08 34.8 0.0 3.8e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CRK31153.1 - 8.2e-07 29.6 0.0 1.6e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK31153.1 - 0.013 15.3 0.0 0.024 14.4 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 CRK31153.1 - 0.031 15.0 0.0 0.059 14.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 CRK31153.1 - 0.047 13.5 0.0 0.075 12.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain AF-4 PF05110.13 CRK31153.1 - 4.3 5.3 7.2 5.5 4.9 7.2 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Complex1_LYR PF05347.15 CRK31154.1 - 4.2e-07 29.9 0.4 6.2e-07 29.4 0.4 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 CRK31154.1 - 0.00026 21.7 0.3 0.00035 21.3 0.3 1.2 1 0 0 1 1 1 1 Complex1_LYR-like DUF3287 PF11690.8 CRK31156.1 - 0.0065 16.2 2.2 0.0065 16.2 2.2 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF3287) JIP_LZII PF16471.5 CRK31156.1 - 0.011 15.9 1.8 0.011 15.9 1.8 3.4 4 1 1 5 5 5 0 JNK-interacting protein leucine zipper II DUF812 PF05667.11 CRK31156.1 - 0.67 8.8 33.6 1.2 7.9 33.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) CDC45 PF02724.14 CRK31157.1 - 0.00074 17.9 0.9 0.001 17.5 0.9 1.1 1 0 0 1 1 1 1 CDC45-like protein Lipase_3 PF01764.25 CRK31157.1 - 0.19 11.6 0.0 2.1 8.2 0.0 2.2 1 1 1 2 2 2 0 Lipase (class 3) Glyco_hydro_31 PF01055.26 CRK31158.1 - 1.1e-97 328.0 5.1 1.6e-97 327.5 5.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Sugar_tr PF00083.24 CRK31158.1 - 2e-69 234.6 22.6 1.5e-68 231.7 21.3 2.0 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK31158.1 - 4.6e-11 42.2 30.6 4.6e-11 42.2 30.6 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF4968 PF16338.5 CRK31158.1 - 6e-05 23.3 0.0 0.00012 22.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4968) Gal_mutarotas_2 PF13802.6 CRK31158.1 - 0.0026 18.0 1.1 0.016 15.5 0.1 2.7 2 1 0 2 2 2 1 Galactose mutarotase-like Glyco_hydro_39 PF01229.17 CRK31159.1 - 1.2e-06 27.4 0.0 1.7e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 Glyco_hydro_cc PF11790.8 CRK31159.1 - 8.9e-06 25.4 0.1 1.4e-05 24.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core DUF2985 PF11204.8 CRK31161.1 - 4.7e-33 113.2 2.0 9.2e-33 112.2 2.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) RgpF PF05045.12 CRK31162.1 - 0.13 11.0 0.0 0.27 9.9 0.0 1.5 2 0 0 2 2 2 0 Rhamnan synthesis protein F GMC_oxred_N PF00732.19 CRK31163.1 - 8.5e-52 176.4 0.0 1.1e-49 169.4 0.0 2.9 2 1 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CRK31163.1 - 4.8e-30 105.0 0.0 7.8e-30 104.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 CRK31163.1 - 4.2e-05 22.8 0.2 8e-05 21.9 0.2 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 CRK31163.1 - 0.00011 21.4 0.0 0.4 9.7 0.0 2.4 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 CRK31163.1 - 0.011 15.3 0.7 0.96 9.0 0.2 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.17 CRK31163.1 - 0.018 14.3 1.2 0.029 13.6 0.2 1.8 2 0 0 2 2 2 0 Thi4 family Trp_halogenase PF04820.14 CRK31163.1 - 0.033 13.1 0.1 0.047 12.5 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_8 PF13450.6 CRK31163.1 - 0.063 13.5 0.1 0.18 12.0 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DnaJ PF00226.31 CRK31164.1 - 4.8e-20 71.5 1.8 8e-20 70.7 1.8 1.4 1 0 0 1 1 1 1 DnaJ domain DUF456 PF04306.13 CRK31164.1 - 0.0046 17.3 1.8 0.0074 16.6 1.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF456) Bacteriocin_IIc PF10439.9 CRK31164.1 - 0.024 14.7 5.0 0.058 13.5 5.0 1.6 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide NmrA PF05368.13 CRK31165.1 - 1e-28 100.5 0.0 1.3e-28 100.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 CRK31165.1 - 8.3e-08 32.3 0.0 1e-07 32.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 CRK31165.1 - 0.04 13.4 0.0 0.66 9.4 0.0 2.1 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family ATP-synt_ab PF00006.25 CRK31167.1 - 9.4e-71 237.8 0.0 1.3e-70 237.3 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 CRK31167.1 - 2.7e-45 153.8 0.2 4.8e-45 152.9 0.2 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 CRK31167.1 - 8.6e-15 55.0 2.8 8.6e-15 55.0 2.8 1.9 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain AAA_22 PF13401.6 CRK31167.1 - 0.0057 16.9 0.0 0.018 15.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain RbcS PF12338.8 CRK31167.1 - 0.1 12.8 0.2 1.6 9.0 0.2 2.5 2 0 0 2 2 2 0 Ribulose-1,5-bisphosphate carboxylase small subunit ATP-synt_ab PF00006.25 CRK31168.1 - 7.6e-51 172.8 0.0 1.2e-50 172.1 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Carb_kinase PF01256.17 CRK31168.1 - 5.6e-40 137.3 0.1 6.2e-39 133.9 0.0 2.3 2 0 0 2 2 2 1 Carbohydrate kinase ATP-synt_ab_N PF02874.23 CRK31168.1 - 1e-14 54.8 4.6 1e-14 54.8 2.8 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain AAA_22 PF13401.6 CRK31168.1 - 0.17 12.2 0.0 0.63 10.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain RbcS PF12338.8 CRK31168.1 - 4.9 7.4 5.9 2.6 8.3 0.6 2.9 3 0 0 3 3 3 0 Ribulose-1,5-bisphosphate carboxylase small subunit Ribosomal_L5_C PF00673.21 CRK31169.1 - 4.9e-22 77.9 0.0 7.2e-22 77.4 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 CRK31169.1 - 1.1e-19 70.5 0.0 3.7e-19 68.8 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L5 Ribosomal_L5_C PF00673.21 CRK31170.1 - 4.9e-22 77.9 0.0 7.2e-22 77.4 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 CRK31170.1 - 1.1e-19 70.5 0.0 3.7e-19 68.8 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L5 LSM PF01423.22 CRK31171.1 - 7.7e-19 67.2 0.0 1.1e-18 66.7 0.0 1.1 1 0 0 1 1 1 1 LSM domain MPC PF03650.13 CRK31172.1 - 8.1e-35 119.3 0.1 1e-34 119.0 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers CPSase_L_D2 PF02786.17 CRK31173.1 - 2.7e-56 190.4 0.1 3.7e-56 190.0 0.1 1.1 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 CRK31173.1 - 1.2e-17 63.9 0.0 2.1e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 CRK31173.1 - 0.00019 21.0 0.0 0.00039 20.0 0.0 1.5 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 CRK31173.1 - 0.018 14.8 0.1 0.029 14.1 0.1 1.4 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 CRK31173.1 - 0.073 13.1 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain Proteasome PF00227.26 CRK31174.1 - 1e-45 155.6 0.1 2.5e-30 105.4 0.0 2.6 3 0 0 3 3 3 2 Proteasome subunit Proteasome_A_N PF10584.9 CRK31174.1 - 4.8e-12 45.3 1.0 5.6e-12 45.1 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature MPC PF03650.13 CRK31176.1 - 6.4e-35 119.6 0.0 8.2e-35 119.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers CPSase_L_D2 PF02786.17 CRK31177.1 - 2.2e-101 337.7 3.5 2.5e-81 272.2 0.4 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 CRK31177.1 - 8.9e-79 261.2 0.1 7.8e-38 129.4 0.0 2.5 2 0 0 2 2 2 2 Biotin carboxylase, N-terminal domain HMGL-like PF00682.19 CRK31177.1 - 5.9e-39 134.2 0.0 2.3e-16 60.2 0.1 3.3 3 0 0 3 3 3 3 HMGL-like PYC_OADA PF02436.18 CRK31177.1 - 3.2e-38 131.5 0.2 5.9e-38 130.6 0.2 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_lipoyl PF00364.22 CRK31177.1 - 5.2e-19 67.8 2.4 5.2e-19 67.8 2.4 2.3 3 0 0 3 3 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 CRK31177.1 - 1.1e-13 51.2 0.0 3.3e-09 36.6 0.0 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 CRK31177.1 - 3.9e-12 46.1 0.3 1.5e-06 27.9 0.1 2.4 2 0 0 2 2 2 2 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 CRK31177.1 - 1e-09 38.0 1.3 3e-06 27.0 0.1 2.9 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp_3 PF02655.14 CRK31177.1 - 3.7e-08 33.6 0.1 6e-05 23.1 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain RimK PF08443.11 CRK31177.1 - 1.3e-07 31.4 0.0 0.0013 18.3 0.0 3.0 2 1 0 2 2 2 2 RimK-like ATP-grasp domain ATPgrasp_ST PF14397.6 CRK31177.1 - 3.2e-07 29.9 0.0 0.039 13.2 0.0 3.2 3 0 0 3 3 3 2 Sugar-transfer associated ATP-grasp ATP-grasp_4 PF13535.6 CRK31177.1 - 0.00033 20.3 0.0 0.028 14.0 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 CRK31177.1 - 0.0017 18.1 0.1 0.36 10.6 0.0 2.6 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain HlyD_D23 PF16576.5 CRK31177.1 - 0.0017 17.6 0.1 0.31 10.2 0.0 2.3 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 CRK31177.1 - 0.0021 18.8 0.3 5.3 7.8 0.0 3.0 3 0 0 3 3 3 2 HlyD family secretion protein NQRA PF05896.11 CRK31177.1 - 0.081 12.3 0.2 0.15 11.5 0.2 1.3 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) DUF2118 PF09891.9 CRK31177.1 - 0.083 12.8 0.0 0.23 11.4 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) RnfC_N PF13375.6 CRK31177.1 - 0.12 12.3 0.4 0.4 10.7 0.4 1.9 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain DUF1623 PF07785.11 CRK31177.1 - 0.13 12.5 2.7 7.6 6.8 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1623) PRP4 PF08799.11 CRK31177.1 - 1.7 8.3 5.3 17 5.0 0.5 2.6 2 0 0 2 2 2 0 pre-mRNA processing factor 4 (PRP4) like DUF5585 PF17823.1 CRK31178.1 - 0.071 12.1 7.2 0.098 11.6 7.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5585) DnaJ PF00226.31 CRK31179.1 - 1.1e-08 35.1 0.4 6.2e-08 32.7 0.0 2.4 3 1 1 4 4 4 1 DnaJ domain SirA PF10747.9 CRK31179.1 - 0.024 15.0 0.0 0.038 14.3 0.0 1.3 1 0 0 1 1 1 0 Sporulation inhibitor of replication protein SirA DNA_pol_phi PF04931.13 CRK31180.1 - 3.2e-169 564.6 28.1 3.2e-169 564.6 28.1 2.8 2 1 0 2 2 2 1 DNA polymerase phi EB1 PF03271.17 CRK31180.1 - 0.0075 16.5 0.1 0.034 14.4 0.1 2.2 1 0 0 1 1 1 1 EB1-like C-terminal motif TetR_C_20 PF17925.1 CRK31180.1 - 0.051 13.9 2.1 0.36 11.2 0.0 3.2 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain ALC PF17527.2 CRK31180.1 - 0.053 13.2 1.5 0.19 11.4 1.5 2.0 1 0 0 1 1 1 0 Phage ALC protein DUF2115 PF09888.9 CRK31180.1 - 0.059 13.9 0.1 1.3 9.6 0.1 2.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) Spore_III_AF PF09581.10 CRK31180.1 - 0.075 13.1 6.2 1.1 9.2 0.7 2.6 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) DNA_pol_phi PF04931.13 CRK31183.1 - 5.2e-154 514.3 34.0 5.2e-154 514.3 34.0 3.1 2 1 0 2 2 2 1 DNA polymerase phi EB1 PF03271.17 CRK31183.1 - 0.0052 17.0 0.0 0.026 14.8 0.0 2.3 1 0 0 1 1 1 1 EB1-like C-terminal motif TetR_C_20 PF17925.1 CRK31183.1 - 0.2 12.0 4.7 0.27 11.6 0.0 3.6 4 0 0 4 4 4 0 Tetracyclin repressor-like, C-terminal domain Crp PF00325.20 CRK31184.1 - 0.11 12.2 0.3 0.3 10.8 0.3 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family Rhodanese PF00581.20 CRK31185.1 - 8.2e-12 45.6 0.0 1.7e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain CwfJ_C_1 PF04677.15 CRK31186.1 - 7.9e-24 83.9 0.0 1.8e-23 82.7 0.0 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 CRK31186.1 - 9.1e-14 52.1 0.1 1.7e-13 51.3 0.1 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 DRIM PF07539.12 CRK31187.1 - 1e-198 661.6 2.6 1.3e-198 661.3 0.0 2.6 3 0 0 3 3 3 1 Down-regulated in metastasis HEAT PF02985.22 CRK31187.1 - 4.6e-07 29.5 3.7 6.4 7.3 0.0 8.4 8 0 0 8 8 8 1 HEAT repeat HEAT_2 PF13646.6 CRK31187.1 - 1.6e-06 28.4 10.3 2.2 8.7 0.0 8.0 8 0 0 8 8 8 2 HEAT repeats DUF3385 PF11865.8 CRK31187.1 - 0.015 15.2 0.1 1.9 8.4 0.1 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3385) HEAT_EZ PF13513.6 CRK31187.1 - 0.099 13.2 2.0 7.8 7.1 0.0 5.3 7 0 0 7 7 7 0 HEAT-like repeat V-ATPase_H_C PF11698.8 CRK31187.1 - 0.7 10.0 4.8 18 5.5 0.0 5.2 6 0 0 6 6 6 0 V-ATPase subunit H TPR_20 PF14561.6 CRK31187.1 - 3.2 8.2 11.7 5.9 7.3 0.4 4.9 6 1 1 7 7 7 0 Tetratricopeptide repeat DUF4890 PF16231.5 CRK31187.1 - 5.9 7.4 11.5 6.6 7.3 9.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4890) zf-DNL PF05180.12 CRK31188.1 - 1.4e-28 98.6 0.4 1.9e-28 98.1 0.4 1.2 1 0 0 1 1 1 1 DNL zinc finger zf-CSL PF05207.13 CRK31188.1 - 0.03 14.0 0.3 0.057 13.1 0.3 1.4 1 0 0 1 1 1 0 CSL zinc finger DUF3408 PF11888.8 CRK31188.1 - 0.17 12.0 0.2 0.35 11.0 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3408) Cullin PF00888.22 CRK31189.1 - 5e-195 649.7 2.9 6.4e-195 649.4 2.9 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 CRK31189.1 - 1.4e-24 85.9 1.5 2e-24 85.4 0.4 2.0 2 0 0 2 2 2 1 Cullin protein neddylation domain GH131_N PF18271.1 CRK31190.1 - 5.9e-62 209.7 0.1 8.9e-62 209.1 0.1 1.2 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain Rhodanese PF00581.20 CRK31191.1 - 6.3e-12 46.0 0.0 1.3e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain CwfJ_C_1 PF04677.15 CRK31192.1 - 1.3e-23 83.2 0.0 2.9e-23 82.0 0.0 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 CRK31192.1 - 1.5e-13 51.4 0.1 2.8e-13 50.6 0.1 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 zf-DNL PF05180.12 CRK31194.1 - 1.2e-28 98.8 0.4 1.9e-28 98.2 0.4 1.3 1 0 0 1 1 1 1 DNL zinc finger zf-CSL PF05207.13 CRK31194.1 - 0.025 14.3 0.3 0.057 13.2 0.3 1.6 1 0 0 1 1 1 0 CSL zinc finger Cullin PF00888.22 CRK31196.1 - 8.5e-196 652.3 2.1 1.1e-195 651.9 2.1 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 CRK31196.1 - 1.2e-24 86.1 1.5 1.9e-24 85.4 0.4 2.1 2 0 0 2 2 2 1 Cullin protein neddylation domain DUF4326 PF14216.6 CRK31196.1 - 0.1 13.4 0.0 0.6 10.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4326) VGPC1_C PF16799.5 CRK31197.1 - 0.14 12.2 0.1 0.26 11.3 0.1 1.4 1 0 0 1 1 1 0 C-terminal membrane-localisation domain of ion-channel, VCN1 PRA1 PF03208.19 CRK31199.1 - 1e-36 125.7 0.7 1.3e-36 125.3 0.7 1.1 1 0 0 1 1 1 1 PRA1 family protein Renin_r PF07850.14 CRK31199.1 - 0.022 15.4 0.3 0.044 14.4 0.0 1.7 2 0 0 2 2 2 0 Renin receptor-like protein DPPIV_N PF00930.21 CRK31200.1 - 1.8e-93 313.1 4.7 5.2e-70 236.0 0.9 2.2 1 1 1 2 2 2 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 CRK31200.1 - 1.6e-53 181.3 2.4 3e-53 180.4 2.4 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 CRK31200.1 - 3.9e-05 23.4 0.9 3.9e-05 23.4 0.9 2.9 2 1 1 3 3 3 1 X-Pro dipeptidyl-peptidase (S15 family) Med3 PF11593.8 CRK31200.1 - 0.049 12.8 18.3 0.11 11.7 18.3 1.5 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Abhydrolase_6 PF12697.7 CRK31200.1 - 1.7 9.2 16.8 0.042 14.5 3.7 3.7 2 1 0 2 2 2 0 Alpha/beta hydrolase family Phage_GPD PF05954.11 CRK31200.1 - 5.2 6.3 6.4 1.1 8.5 0.6 2.8 4 0 0 4 4 4 0 Phage late control gene D protein (GPD) Clathrin PF00637.20 CRK31201.1 - 6.1e-201 658.4 31.6 6.6e-32 110.3 3.5 7.5 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 CRK31201.1 - 1.8e-33 113.2 0.2 7.6e-07 29.1 0.0 6.7 6 0 0 6 6 6 6 Clathrin propeller repeat Clathrin_H_link PF13838.6 CRK31201.1 - 4.1e-32 109.9 0.7 1.6e-31 108.0 0.1 2.5 2 0 0 2 2 2 1 Clathrin-H-link Coatomer_WDAD PF04053.14 CRK31201.1 - 3.1e-05 23.2 7.0 0.25 10.3 0.2 4.9 5 0 0 5 5 5 2 Coatomer WD associated region TPR_7 PF13176.6 CRK31201.1 - 3.8e-05 23.4 5.0 10 6.4 0.0 7.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 CRK31201.1 - 0.00026 21.6 5.1 30 5.8 0.0 7.9 8 0 0 8 8 8 0 Tetratricopeptide repeat PQQ_2 PF13360.6 CRK31201.1 - 0.0018 17.9 0.1 0.06 12.9 0.1 2.5 2 0 0 2 2 2 1 PQQ-like domain TPR_8 PF13181.6 CRK31201.1 - 0.0038 17.3 4.3 1.9 8.9 0.0 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat PPR PF01535.20 CRK31201.1 - 0.0091 16.2 1.2 39 4.8 0.0 5.2 4 0 0 4 4 4 0 PPR repeat Clathrin-link PF09268.10 CRK31201.1 - 0.067 12.6 0.3 0.17 11.3 0.3 1.8 1 0 0 1 1 1 0 Clathrin, heavy-chain linker Vps39_1 PF10366.9 CRK31201.1 - 0.13 12.5 4.5 2.4 8.5 0.0 5.2 5 1 1 6 6 6 0 Vacuolar sorting protein 39 domain 1 TPR_1 PF00515.28 CRK31201.1 - 5.5 7.0 10.3 14 5.7 0.0 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF1640 PF07798.11 CRK31202.1 - 7.3e-54 182.5 7.9 1.2e-53 181.8 7.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) GNAT_acetyltr_2 PF13718.6 CRK31202.1 - 0.16 11.4 0.7 0.34 10.3 0.1 1.7 1 1 1 2 2 2 0 GNAT acetyltransferase 2 PseudoU_synth_1 PF01416.20 CRK31202.1 - 0.16 12.4 0.2 0.83 10.1 0.0 2.1 1 1 1 2 2 2 0 tRNA pseudouridine synthase Cluap1 PF10234.9 CRK31202.1 - 0.22 10.9 6.8 0.32 10.3 6.8 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 cwf21 PF08312.12 CRK31202.1 - 0.36 11.0 3.7 0.42 10.8 2.1 2.0 2 1 0 2 2 2 0 cwf21 domain Metal_resist PF13801.6 CRK31202.1 - 4.6 7.4 6.1 0.46 10.7 0.6 2.3 3 0 0 3 3 3 0 Heavy-metal resistance Phytase PF02333.15 CRK31203.1 - 7e-69 232.6 0.0 1.4e-68 231.6 0.0 1.4 1 0 0 1 1 1 1 Phytase EGF_2 PF07974.13 CRK31203.1 - 4.1e-07 30.2 35.4 0.0028 18.0 15.0 2.5 2 0 0 2 2 2 2 EGF-like domain EGF PF00008.27 CRK31203.1 - 0.99 9.8 27.4 0.35 11.2 8.0 2.6 2 0 0 2 2 2 0 EGF-like domain Methyltransf_23 PF13489.6 CRK31204.1 - 8.6e-05 22.4 0.0 0.00013 21.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CRK31204.1 - 0.00093 18.6 0.0 0.0016 17.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 CRK31204.1 - 0.001 19.7 0.0 0.0024 18.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK31204.1 - 0.033 14.9 0.1 0.13 13.0 0.1 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 CRK31204.1 - 0.053 14.2 0.0 0.11 13.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain NAD_Gly3P_dh_N PF01210.23 CRK31205.1 - 1.3e-43 148.7 0.0 3.8e-43 147.2 0.0 1.7 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 CRK31205.1 - 5.6e-43 146.6 0.1 9.3e-43 145.9 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus K_oxygenase PF13434.6 CRK31205.1 - 0.2 10.7 0.0 0.31 10.1 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) hDGE_amylase PF14701.6 CRK31206.1 - 8.6e-181 601.8 0.0 1.1e-180 601.5 0.0 1.1 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 CRK31206.1 - 5.2e-120 400.9 0.2 9.1e-120 400.1 0.0 1.4 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 CRK31206.1 - 1.7e-88 296.5 0.0 3.6e-88 295.5 0.0 1.6 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 CRK31206.1 - 9.5e-30 102.6 0.0 2.1e-29 101.5 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.24 CRK31206.1 - 0.031 13.8 0.0 0.47 10.0 0.0 2.3 2 0 0 2 2 2 0 Alpha amylase, catalytic domain CFEM PF05730.11 CRK31207.1 - 0.029 14.4 4.7 0.058 13.5 4.7 1.5 1 0 0 1 1 1 0 CFEM domain EthD PF07110.11 CRK31208.1 - 7e-19 68.8 0.8 8.3e-19 68.5 0.8 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 CRK31208.1 - 5.3e-07 30.1 0.0 7.7e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase Peptidase_C48 PF02902.19 CRK31210.1 - 6.5e-18 65.4 0.0 1.7e-17 64.0 0.0 1.7 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain SLX9 PF15341.6 CRK31211.1 - 1.3e-36 125.9 1.4 1.6e-36 125.6 1.4 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 Cep57_CLD_2 PF14197.6 CRK31211.1 - 0.059 13.5 0.2 0.1 12.7 0.2 1.3 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 ThiF PF00899.21 CRK31212.1 - 2e-60 204.2 0.0 3.1e-60 203.6 0.0 1.2 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 CRK31212.1 - 2.2e-12 47.4 0.0 5.4e-12 46.2 0.0 1.7 2 0 0 2 2 2 1 Rhodanese-like domain Shikimate_DH PF01488.20 CRK31212.1 - 0.037 14.1 0.2 0.65 10.1 0.1 2.3 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 CRK31212.1 - 0.051 14.0 0.0 0.12 12.8 0.0 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding GIDA PF01134.22 CRK31212.1 - 0.53 9.3 1.9 0.81 8.7 1.9 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Pam17 PF08566.10 CRK31215.1 - 7.2e-63 211.3 0.0 9.6e-63 210.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 Chromo PF00385.24 CRK31217.1 - 3.9e-08 33.1 0.1 2e-07 30.8 0.1 2.1 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain VIT1 PF01988.19 CRK31217.1 - 0.029 14.2 0.1 0.048 13.5 0.1 1.4 1 0 0 1 1 1 0 VIT family PIP5K PF01504.18 CRK31220.1 - 1.8e-44 152.0 0.0 1.4e-43 149.1 0.0 1.9 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase SET PF00856.28 CRK31222.1 - 7.4e-13 49.2 0.0 3.9e-12 46.9 0.0 2.0 1 1 0 1 1 1 1 SET domain TPR_MalT PF17874.1 CRK31222.1 - 0.056 12.8 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 MalT-like TPR region Pectate_lyase PF03211.13 CRK31224.1 - 7.1e-84 280.4 1.9 8.6e-84 280.1 1.9 1.0 1 0 0 1 1 1 1 Pectate lyase DUF2199 PF09965.9 CRK31227.1 - 0.036 14.1 0.7 0.17 11.9 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2199) PAN_4 PF14295.6 CRK31229.1 - 0.00078 19.3 0.2 0.0021 17.9 0.2 1.8 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 CRK31229.1 - 0.0035 17.3 0.0 0.011 15.7 0.0 1.8 1 0 0 1 1 1 1 PAN domain B277 PF17623.2 CRK31229.1 - 0.23 10.5 1.2 0.38 9.8 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF1206 PF06724.11 CRK31231.1 - 6 7.0 8.6 0.68 10.0 1.6 2.4 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1206) Oxidored_molyb PF00174.19 CRK31233.1 - 3.7e-46 156.9 0.0 6.6e-46 156.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 CRK31233.1 - 5.4e-22 78.3 3.6 1e-21 77.4 3.6 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Glyco_hydro81C PF17652.1 CRK31236.1 - 6e-160 532.2 9.6 7.5e-160 531.9 9.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 CRK31236.1 - 4.8e-110 367.7 0.2 7e-110 367.2 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain AtuA PF07287.11 CRK31242.1 - 4.9e-37 127.5 0.0 5.5e-37 127.3 0.0 1.0 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA Zeta_toxin PF06414.12 CRK31242.1 - 0.18 11.1 0.0 0.36 10.1 0.0 1.4 2 0 0 2 2 2 0 Zeta toxin CoA_transf_3 PF02515.17 CRK31243.1 - 7.1e-42 143.8 0.4 1.6e-41 142.6 0.1 1.7 2 0 0 2 2 2 1 CoA-transferase family III Aminotran_1_2 PF00155.21 CRK31244.1 - 2.7e-85 286.7 0.0 4.5e-85 286.0 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II ATP_transf PF09830.9 CRK31244.1 - 7.5e-11 42.0 0.0 1.8e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 ATP adenylyltransferase Syntaxin-18_N PF10496.9 CRK31244.1 - 3e-09 37.0 0.8 8.6e-09 35.5 0.8 1.8 1 0 0 1 1 1 1 SNARE-complex protein Syntaxin-18 N-terminus Fungal_trans PF04082.18 CRK31244.1 - 6.3e-05 22.1 0.1 0.003 16.6 0.0 2.6 1 1 1 2 2 2 1 Fungal specific transcription factor domain MFS_1 PF07690.16 CRK31245.1 - 8.5e-50 169.6 22.3 8.5e-50 169.6 22.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK31245.1 - 1.7e-08 33.8 11.3 1.7e-08 33.8 11.3 2.6 3 1 0 3 3 3 1 Sugar (and other) transporter OAD_gamma PF04277.13 CRK31245.1 - 0.13 12.9 0.0 2.3 8.9 0.0 2.5 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain OATP PF03137.20 CRK31245.1 - 0.45 8.7 5.7 0.11 10.7 1.8 1.7 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Clr5 PF14420.6 CRK31246.1 - 1.1e-25 89.5 1.3 2.7e-25 88.3 1.3 1.7 1 0 0 1 1 1 1 Clr5 domain Conotoxin PF02950.17 CRK31248.1 - 0.042 14.9 0.7 0.042 14.9 0.7 2.1 1 1 1 2 2 2 0 Conotoxin NIR_SIR PF01077.22 CRK31249.1 - 7.2e-56 188.1 0.0 1.4e-49 167.7 0.1 2.3 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 CRK31249.1 - 2.9e-29 100.7 0.1 9.2e-15 54.3 0.1 2.5 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 CRK31249.1 - 9.9e-19 68.0 0.0 2.2e-18 66.8 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin RabGAP-TBC PF00566.18 CRK31251.1 - 2.9e-21 76.1 0.0 6.3e-17 61.9 0.0 2.1 1 1 1 2 2 2 2 Rab-GTPase-TBC domain HisKA PF00512.25 CRK31252.1 - 2.8e-08 33.7 0.6 4.2e-06 26.7 0.0 2.4 1 1 1 2 2 2 2 His Kinase A (phospho-acceptor) domain Pkinase PF00069.25 CRK31253.1 - 1e-57 195.6 0.0 1.1e-57 195.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK31253.1 - 9.7e-25 87.3 0.0 1.1e-24 87.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CRK31253.1 - 5.6e-08 32.4 0.0 6.7e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CRK31253.1 - 4.8e-05 22.3 0.0 6.5e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CRK31253.1 - 0.0002 21.4 0.1 0.00031 20.8 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CRK31253.1 - 0.00025 20.4 0.0 0.00038 19.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Integrase_H2C2 PF17921.1 CRK31253.1 - 0.13 12.4 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 Integrase zinc binding domain Ion_trans PF00520.31 CRK31254.1 - 0.0084 15.4 7.8 0.0084 15.4 7.8 1.8 2 0 0 2 2 2 1 Ion transport protein DUF108 PF01958.18 CRK31254.1 - 0.059 13.7 0.2 0.2 12.0 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function DUF108 DUF805 PF05656.14 CRK31254.1 - 2.2 8.8 7.7 9.9 6.6 7.7 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF805) PH_11 PF15413.6 CRK31256.1 - 4.6e-07 30.2 0.1 8.2e-07 29.4 0.1 1.4 1 1 0 1 1 1 1 Pleckstrin homology domain PBD PF00786.28 CRK31256.1 - 2.4e-05 24.6 1.4 5.3e-05 23.5 1.4 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain PH PF00169.29 CRK31256.1 - 0.00035 21.0 0.1 0.00069 20.1 0.1 1.5 1 1 0 1 1 1 1 PH domain p450 PF00067.22 CRK31257.1 - 1.1e-60 205.7 0.0 8.5e-30 103.9 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 BRD4_CDT PF17105.5 CRK31257.1 - 0.091 12.4 0.7 0.2 11.3 0.7 1.6 1 0 0 1 1 1 0 C-terminal domain of bromodomain protein 4 SQHop_cyclase_C PF13243.6 CRK31258.1 - 9.6e-49 166.2 0.1 2.7e-48 164.7 0.1 1.6 2 0 0 2 2 2 1 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 CRK31258.1 - 8.3e-41 140.0 8.2 2.2e-36 125.5 1.1 3.5 2 1 0 3 3 3 2 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 CRK31258.1 - 7.2e-27 92.8 9.1 1.1e-09 37.8 0.2 5.8 6 0 0 6 6 6 3 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 CRK31258.1 - 0.0016 17.6 0.0 1.6 7.7 0.0 3.0 1 1 1 3 3 3 2 A-macroglobulin TED domain Fungal_trans PF04082.18 CRK31259.1 - 5.9e-08 32.1 0.1 6.3e-08 32.0 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_M24 PF00557.24 CRK31262.1 - 1.6e-40 139.1 0.0 1.9e-40 138.8 0.0 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF3793 PF12672.7 CRK31262.1 - 0.16 12.0 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3793) zf-C3HC4 PF00097.25 CRK31263.1 - 8e-06 25.6 10.8 1.3e-05 24.9 10.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CRK31263.1 - 4.6e-05 23.7 11.0 7.2e-05 23.0 11.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CRK31263.1 - 7e-05 22.6 10.6 0.00011 21.9 10.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CRK31263.1 - 0.00054 19.9 5.4 0.00091 19.2 5.4 1.4 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 CRK31263.1 - 0.006 16.4 9.7 0.01 15.7 9.7 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 CRK31263.1 - 0.013 15.4 11.3 0.029 14.2 11.3 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_Tnp_IS91 PF14319.6 CRK31263.1 - 0.046 13.8 2.4 0.098 12.7 2.4 1.6 1 0 0 1 1 1 0 Transposase zinc-binding domain zf-C3HC4_4 PF15227.6 CRK31263.1 - 0.063 13.5 9.7 0.11 12.7 9.7 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 CRK31263.1 - 0.5 10.4 11.8 1.9 8.5 11.9 1.8 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING_10 PF16685.5 CRK31263.1 - 0.72 10.0 7.6 1.6 8.9 7.6 1.6 1 1 0 1 1 1 0 zinc RING finger of MSL2 S1-P1_nuclease PF02265.16 CRK31264.1 - 2.3e-47 162.0 0.1 2.5e-47 161.8 0.1 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease Lipase_GDSL_2 PF13472.6 CRK31265.1 - 3.8e-21 76.3 0.1 4.9e-21 75.9 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 CRK31265.1 - 1.7e-09 38.0 0.0 1.9e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 CRK31265.1 - 3.9e-07 30.4 0.0 6.5e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family S-AdoMet_synt_N PF00438.20 CRK31266.1 - 1.7e-41 140.9 1.2 3.4e-41 139.9 0.1 1.9 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain S-AdoMet_synt_M PF02772.16 CRK31266.1 - 3e-39 134.0 0.0 6.2e-39 133.0 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain AdoMet_Synthase PF01941.19 CRK31266.1 - 0.052 12.3 0.4 0.34 9.7 0.1 2.1 1 1 1 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) ArgJ PF01960.18 CRK31267.1 - 9.5e-46 156.2 0.0 1.1e-45 156.1 0.0 1.0 1 0 0 1 1 1 1 ArgJ family Exo_endo_phos PF03372.23 CRK31269.1 - 0.039 13.5 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Dermcidin PF15291.6 CRK31270.1 - 0.048 14.2 0.2 0.07 13.7 0.2 1.3 1 0 0 1 1 1 0 Dermcidin, antibiotic peptide RabGAP-TBC PF00566.18 CRK31271.1 - 7e-20 71.6 0.0 9.2e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PP-binding PF00550.25 CRK31273.1 - 0.013 15.8 0.1 0.89 10.0 0.0 2.4 2 0 0 2 2 2 0 Phosphopantetheine attachment site Drf_FH3 PF06367.16 CRK31273.1 - 0.031 13.9 0.7 0.28 10.8 1.1 2.3 2 1 0 2 2 2 0 Diaphanous FH3 Domain DUF1779 PF08680.10 CRK31273.1 - 0.045 13.9 0.1 0.077 13.2 0.1 1.4 1 0 0 1 1 1 0 TATA-box binding YqzH PF14164.6 CRK31273.1 - 0.051 13.7 0.1 0.74 9.9 0.0 2.6 2 1 0 2 2 2 0 YqzH-like protein WD40 PF00400.32 CRK31274.1 - 9.9e-07 29.4 0.1 0.059 14.3 0.1 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat HPP PF04982.13 CRK31275.1 - 2e-39 134.5 9.7 2e-39 134.5 9.7 1.6 2 0 0 2 2 2 1 HPP family tRNA-synt_2 PF00152.20 CRK31276.1 - 1.2e-09 37.7 0.1 1.3e-09 37.6 0.1 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF3738 PF12543.8 CRK31276.1 - 0.085 13.0 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3738) Ion_trans PF00520.31 CRK31277.1 - 0.045 13.0 3.8 0.08 12.2 3.7 1.4 1 1 0 1 1 1 0 Ion transport protein CENP-B_dimeris PF09026.10 CRK31277.1 - 0.083 13.3 0.1 0.11 12.9 0.1 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF4014 PF13198.6 CRK31277.1 - 0.4 11.1 5.0 3.1 8.3 1.9 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF4014) CP2 PF04516.15 CRK31279.1 - 1e-82 276.9 0.0 2.1e-82 275.9 0.0 1.5 2 0 0 2 2 2 1 CP2 transcription factor Tektin PF03148.14 CRK31279.1 - 0.023 13.5 0.0 0.035 12.9 0.0 1.2 1 0 0 1 1 1 0 Tektin family TMF_DNA_bd PF12329.8 CRK31279.1 - 0.041 13.9 0.7 0.086 12.9 0.7 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding AKNA PF12443.8 CRK31279.1 - 0.1 13.3 0.5 0.52 11.0 0.2 2.5 2 0 0 2 2 2 0 AT-hook-containing transcription factor Nop PF01798.18 CRK31281.1 - 2.2e-81 272.7 0.0 3.9e-81 271.9 0.0 1.4 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 CRK31281.1 - 1.4e-16 60.6 0.0 1.4e-16 60.6 0.0 2.1 2 0 0 2 2 2 1 NOP5NT (NUC127) domain RNA_polI_A34 PF08208.11 CRK31281.1 - 1.2 9.2 24.9 2.2 8.3 24.9 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 BEX PF04538.12 CRK31281.1 - 1.9 9.1 15.3 3.8 8.1 15.3 1.5 1 0 0 1 1 1 0 Brain expressed X-linked like family Vps4_C PF09336.10 CRK31282.1 - 4.6e-25 87.4 0.5 1.1e-24 86.1 0.5 1.7 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA PF00004.29 CRK31282.1 - 1.2e-22 80.7 0.0 2.1e-22 80.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MIT PF04212.18 CRK31282.1 - 6.9e-17 61.3 2.4 1.2e-16 60.5 2.4 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 CRK31282.1 - 5.5e-08 32.5 0.0 2.3e-07 30.5 0.0 2.0 2 0 0 2 2 2 1 AAA+ lid domain Barstar PF01337.18 CRK31283.1 - 0.042 13.9 0.0 0.09 12.8 0.0 1.6 1 0 0 1 1 1 0 Barstar (barnase inhibitor) JAB PF01398.21 CRK31285.1 - 6e-15 55.2 0.0 1.2e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.11 CRK31285.1 - 6.3e-08 32.8 0.0 1.2e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.6 CRK31285.1 - 1.2e-05 25.0 0.0 4.4e-05 23.2 0.0 1.9 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF3618 PF12277.8 CRK31285.1 - 0.021 15.0 2.3 0.045 14.0 2.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3618) DUF5014 PF16406.5 CRK31285.1 - 0.068 13.4 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5014) Aldo_ket_red PF00248.21 CRK31287.1 - 1.7e-30 106.3 0.0 1.9e-30 106.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FliG_M PF14841.6 CRK31287.1 - 0.00031 20.9 0.3 0.00048 20.3 0.3 1.2 1 0 0 1 1 1 1 FliG middle domain ALAD PF00490.21 CRK31288.1 - 3.3e-62 210.5 0.0 3.6e-62 210.3 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase LIM_bind PF01803.16 CRK31289.1 - 6e-09 35.8 1.9 9.9e-09 35.1 0.0 2.0 2 0 0 2 2 2 1 LIM-domain binding protein BSD PF03909.17 CRK31290.1 - 6.7e-29 99.7 2.3 2.5e-13 49.8 0.1 2.6 3 0 0 3 3 3 2 BSD domain Glyco_hydro_11 PF00457.17 CRK31290.1 - 0.015 14.9 0.1 0.024 14.3 0.1 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 11 PRO8NT PF08082.11 CRK31290.1 - 0.018 15.0 0.0 0.03 14.3 0.0 1.3 1 0 0 1 1 1 0 PRO8NT (NUC069), PrP8 N-terminal domain YccF PF03733.13 CRK31293.1 - 8.5e-10 39.2 17.8 4.4e-09 36.9 2.7 2.6 3 0 0 3 3 3 2 Inner membrane component domain Cation_ATPase PF13246.6 CRK31297.1 - 0.00043 20.3 0.0 0.0008 19.4 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CRK31297.1 - 0.012 15.9 0.1 0.022 15.0 0.0 1.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Phage_TAC_2 PF06894.11 CRK31297.1 - 0.043 13.6 0.0 0.072 12.9 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage lambda tail assembly chaperone, TAC, protein G Mob1_phocein PF03637.17 CRK31300.1 - 2.7e-37 128.4 0.0 5.6e-37 127.3 0.0 1.5 1 1 0 1 1 1 1 Mob1/phocein family Ribosomal_L5e PF17144.4 CRK31304.1 - 4.6e-45 153.5 0.0 7.4e-45 152.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 CRK31304.1 - 2.1e-33 115.1 5.9 3e-33 114.6 5.9 1.2 1 0 0 1 1 1 1 Ribosomal L18 C-terminal region 2-oxoacid_dh PF00198.23 CRK31309.1 - 1.3e-79 267.0 0.1 1.9e-79 266.4 0.1 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 CRK31309.1 - 1.8e-18 66.1 2.2 3.6e-18 65.2 2.2 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 CRK31309.1 - 0.00041 20.1 0.6 0.34 10.8 0.1 2.4 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.6 CRK31309.1 - 0.002 18.8 0.5 2.2 9.0 0.1 2.4 1 1 1 2 2 2 2 HlyD family secretion protein RnfC_N PF13375.6 CRK31309.1 - 0.029 14.3 1.3 1.1 9.3 0.0 3.1 1 1 1 3 3 3 0 RnfC Barrel sandwich hybrid domain GCV_H PF01597.19 CRK31309.1 - 0.036 13.9 0.3 0.081 12.8 0.3 1.6 1 0 0 1 1 1 0 Glycine cleavage H-protein FAM76 PF16046.5 CRK31309.1 - 0.7 9.2 7.1 11 5.2 5.2 2.1 2 0 0 2 2 2 0 FAM76 protein Lin-8 PF03353.15 CRK31309.1 - 0.84 9.1 6.9 1.2 8.6 6.9 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Presenilin PF01080.17 CRK31309.1 - 0.98 8.1 6.7 1.4 7.6 6.7 1.1 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 CRK31309.1 - 1.2 7.7 6.5 1.6 7.4 6.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Apt1 PF10351.9 CRK31309.1 - 2.2 7.1 9.7 3 6.6 9.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain AAA PF00004.29 CRK31311.1 - 5e-15 56.1 0.0 8.3e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CRK31311.1 - 1.1e-08 35.7 0.0 1e-07 32.5 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CRK31311.1 - 1.4e-07 31.8 0.0 3.1e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain BAH PF01426.18 CRK31311.1 - 1.2e-06 28.4 0.0 2.9e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 BAH domain AAA_19 PF13245.6 CRK31311.1 - 0.0051 17.2 0.0 0.012 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CRK31311.1 - 0.023 15.2 0.0 0.052 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 CRK31311.1 - 0.039 13.9 0.0 0.98 9.3 0.0 2.2 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_11 PF13086.6 CRK31311.1 - 0.043 13.6 0.1 0.086 12.6 0.0 1.5 2 0 0 2 2 2 0 AAA domain PIF1 PF05970.14 CRK31311.1 - 0.11 11.7 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase DUF2075 PF09848.9 CRK31311.1 - 0.17 11.1 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.29 CRK31312.1 - 5.7e-15 55.9 0.0 1e-14 55.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_10 PF17872.1 CRK31312.1 - 1.1e-10 41.5 0.0 2.9e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 AAA lid domain AAA_16 PF13191.6 CRK31312.1 - 6.7e-09 36.4 0.0 1.4e-07 32.1 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CRK31312.1 - 5.7e-08 33.1 0.0 4.3e-07 30.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain BAH PF01426.18 CRK31312.1 - 9.1e-08 32.0 0.0 2e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 BAH domain AAA_19 PF13245.6 CRK31312.1 - 0.0045 17.3 0.0 0.016 15.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CRK31312.1 - 0.026 15.1 0.0 0.054 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 CRK31312.1 - 0.047 13.5 0.1 0.12 12.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 CRK31312.1 - 0.048 13.6 0.0 1.3 8.9 0.0 2.4 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea PIF1 PF05970.14 CRK31312.1 - 0.14 11.3 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase WD40 PF00400.32 CRK31313.1 - 1.6e-42 142.7 22.6 2.5e-08 34.4 0.3 7.7 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK31313.1 - 0.0001 22.6 0.2 22 5.4 0.1 4.9 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CRK31313.1 - 0.011 14.4 2.8 12 4.4 0.0 4.1 1 1 3 4 4 4 0 Nucleoporin Nup120/160 W_rich_C PF07483.11 CRK31313.1 - 0.087 13.0 0.4 1.2 9.3 0.1 2.8 3 0 0 3 3 3 0 Tryptophan-rich Synechocystis species C-terminal domain Ank_5 PF13857.6 CRK31314.1 - 9.7e-27 92.7 3.1 6.1e-08 32.8 0.3 4.2 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 CRK31314.1 - 2e-24 85.6 7.3 6.1e-07 29.9 0.1 5.2 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 CRK31314.1 - 2.8e-24 85.5 0.2 2e-13 50.7 0.6 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CRK31314.1 - 8.2e-20 68.8 0.5 0.0055 17.1 0.0 5.8 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 CRK31314.1 - 5.6e-15 55.0 2.8 0.0075 16.7 0.2 5.3 5 0 0 5 5 5 4 Ankyrin repeat TMF_TATA_bd PF12325.8 CRK31315.1 - 1.7e-40 137.8 7.8 1.7e-40 137.8 7.8 6.1 3 2 2 5 5 5 2 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 CRK31315.1 - 3.3e-12 46.2 8.1 3.3e-12 46.2 8.1 7.4 4 3 1 6 6 6 1 TATA element modulatory factor 1 DNA binding Tropomyosin_1 PF12718.7 CRK31315.1 - 0.0042 17.2 9.0 0.0042 17.2 9.0 5.7 3 1 2 5 5 5 2 Tropomyosin like ATG16 PF08614.11 CRK31315.1 - 0.0083 16.4 5.8 0.0083 16.4 5.8 5.5 3 1 2 5 5 5 2 Autophagy protein 16 (ATG16) Holin_BhlA PF10960.8 CRK31315.1 - 0.12 12.4 1.5 0.38 10.8 0.3 2.6 2 0 0 2 2 2 0 BhlA holin family Mucin PF01456.17 CRK31315.1 - 0.21 11.5 10.5 0.47 10.4 10.5 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Leucyl-specific PF14795.6 CRK31315.1 - 3.1 7.9 4.9 3.5 7.8 1.8 2.9 2 0 0 2 2 2 0 Leucine-tRNA synthetase-specific domain DUF948 PF06103.11 CRK31315.1 - 3.7 7.9 6.8 23 5.4 0.6 4.6 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) JAB PF01398.21 CRK31318.1 - 1.9e-14 53.6 0.0 2.6e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 CRK31318.1 - 0.032 14.6 0.1 0.12 12.8 0.0 2.0 3 0 0 3 3 3 0 Maintenance of mitochondrial structure and function DENN PF02141.21 CRK31319.1 - 1e-20 74.5 0.0 1.5e-20 74.0 0.0 1.2 1 0 0 1 1 1 1 DENN (AEX-3) domain Importin_rep_4 PF18808.1 CRK31322.1 - 1.7e-19 69.9 0.5 8.5e-16 58.0 0.1 3.3 2 1 1 3 3 3 2 Importin repeat HEAT PF02985.22 CRK31322.1 - 8.6e-07 28.7 0.3 0.0035 17.5 0.0 4.0 4 0 0 4 4 4 2 HEAT repeat IFRD PF05004.13 CRK31322.1 - 0.062 12.4 0.7 1.7 7.6 0.0 2.1 1 1 1 2 2 2 0 Interferon-related developmental regulator (IFRD) Cohesin_HEAT PF12765.7 CRK31322.1 - 0.078 13.3 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 HEAT repeat associated with sister chromatid cohesion Sterol-sensing PF12349.8 CRK31322.1 - 0.11 12.4 0.1 3 7.7 0.0 2.1 2 0 0 2 2 2 0 Sterol-sensing domain of SREBP cleavage-activation GDPD PF03009.17 CRK31324.1 - 1.1e-59 202.3 0.0 1.9e-59 201.5 0.0 1.4 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 CRK31324.1 - 9.4e-39 131.9 0.7 4.2e-17 62.5 0.1 4.4 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CRK31324.1 - 2.3e-23 82.2 4.2 5.2e-09 36.5 0.1 6.2 4 2 1 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 CRK31324.1 - 1.2e-20 73.3 0.5 5.5e-07 29.7 0.0 5.6 3 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CRK31324.1 - 2.7e-17 61.1 2.9 0.00083 19.6 0.0 8.3 9 0 0 9 9 9 3 Ankyrin repeat SPX PF03105.19 CRK31324.1 - 8.9e-17 62.1 6.5 1.8e-08 34.8 0.1 3.6 3 1 1 4 4 4 3 SPX domain Ank PF00023.30 CRK31324.1 - 7.1e-15 54.7 6.4 0.0012 19.2 0.0 6.8 7 0 0 7 7 7 3 Ankyrin repeat AAA PF00004.29 CRK31327.1 - 4.8e-28 98.2 0.0 7.7e-28 97.5 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CRK31327.1 - 1.2e-07 31.4 0.2 2.9e-07 30.2 0.2 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 CRK31327.1 - 0.099 12.8 5.0 0.27 11.4 1.5 2.1 1 1 1 2 2 2 0 AAA domain (Cdc48 subfamily) Ank_4 PF13637.6 CRK31328.1 - 0.00018 22.0 0.0 0.0003 21.3 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 CRK31328.1 - 0.0014 18.9 0.0 0.005 17.1 0.0 1.6 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CRK31328.1 - 0.0097 16.5 0.0 0.033 14.8 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 CRK31328.1 - 0.054 14.0 0.3 12 6.5 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeat Pkinase PF00069.25 CRK31332.1 - 2.6e-40 138.5 0.0 2.9e-40 138.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK31332.1 - 3.5e-21 75.6 0.0 4.1e-21 75.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CRK31332.1 - 0.0011 18.3 0.0 0.0016 17.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CRK31332.1 - 0.0018 18.2 0.0 0.0033 17.4 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 CRK31332.1 - 0.0041 16.8 0.0 0.13 11.9 0.0 2.0 1 1 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 CRK31332.1 - 0.0097 15.2 0.0 0.42 9.9 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 CRK31332.1 - 0.013 14.5 0.0 0.022 13.7 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Choline_kinase PF01633.20 CRK31332.1 - 0.062 12.9 0.0 0.093 12.3 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.11 CRK31332.1 - 0.1 11.5 0.1 0.22 10.4 0.1 1.6 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Pkinase_fungal PF17667.1 CRK31332.1 - 0.21 10.3 0.0 0.26 10.0 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Abhydrolase_3 PF07859.13 CRK31334.1 - 1.4e-09 38.1 0.5 6.9e-08 32.6 0.5 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CRK31334.1 - 2.1e-08 33.9 0.0 5.6e-08 32.5 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 CRK31334.1 - 7.4e-08 32.2 0.0 1.4e-06 28.0 0.0 2.7 2 1 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 CRK31334.1 - 9e-06 25.5 0.1 0.0085 15.8 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CRK31334.1 - 0.00027 20.3 0.0 0.66 9.2 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 DUF829 PF05705.14 CRK31334.1 - 0.0046 16.9 0.0 0.0053 16.7 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Ser_hydrolase PF06821.13 CRK31334.1 - 0.017 15.0 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase YjeF_N PF03853.15 CRK31334.1 - 0.11 12.4 0.1 0.3 10.9 0.0 1.7 2 0 0 2 2 2 0 YjeF-related protein N-terminus Abhydrolase_2 PF02230.16 CRK31334.1 - 0.22 11.3 0.0 0.34 10.7 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 CRK31334.1 - 0.8 10.3 10.0 48 4.5 10.0 2.1 1 1 0 1 1 1 0 Alpha/beta hydrolase family MFS_1 PF07690.16 CRK31335.1 - 2.5e-14 53.0 7.0 3e-14 52.7 7.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK31335.1 - 0.035 13.0 0.1 0.047 12.5 0.1 1.3 1 0 0 1 1 1 0 Sugar (and other) transporter Shisa PF13908.6 CRK31336.1 - 0.00025 21.4 0.5 0.00035 20.9 0.4 1.4 1 1 0 1 1 1 1 Wnt and FGF inhibitory regulator TMEM132D_C PF15706.5 CRK31336.1 - 0.00025 20.7 0.0 0.00037 20.2 0.0 1.3 1 0 0 1 1 1 1 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Adeno_E3_CR2 PF02439.15 CRK31336.1 - 0.0011 18.6 8.9 0.0011 18.6 8.9 1.6 2 0 0 2 2 2 1 Adenovirus E3 region protein CR2 Herpes_gE PF02480.16 CRK31336.1 - 0.0045 15.8 0.0 0.0058 15.4 0.0 1.0 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Rax2 PF12768.7 CRK31336.1 - 0.025 14.0 0.0 0.031 13.7 0.0 1.1 1 0 0 1 1 1 0 Cortical protein marker for cell polarity EphA2_TM PF14575.6 CRK31336.1 - 0.034 15.0 0.0 0.16 12.9 0.0 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Mid2 PF04478.12 CRK31336.1 - 0.093 12.6 0.1 0.12 12.2 0.1 1.2 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF4448 PF14610.6 CRK31336.1 - 0.14 11.9 0.0 0.18 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Mucin PF01456.17 CRK31336.1 - 0.17 11.9 1.6 0.25 11.3 1.6 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein GMC_oxred_C PF05199.13 CRK31338.1 - 1.3e-21 77.6 0.2 2.2e-21 76.9 0.2 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 CRK31338.1 - 1.6e-15 57.3 0.0 7.6e-14 51.8 0.0 2.3 2 0 0 2 2 2 2 GMC oxidoreductase FAD_binding_2 PF00890.24 CRK31338.1 - 0.037 13.1 0.0 0.064 12.3 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Beta_helix PF13229.6 CRK31339.1 - 4.7e-10 39.5 14.8 7.6e-10 38.8 10.9 2.2 1 1 1 2 2 2 2 Right handed beta helix region Chondroitinas_B PF14592.6 CRK31339.1 - 1.6e-05 24.0 0.0 3.5e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Chondroitinase B DUF1565 PF07602.11 CRK31339.1 - 0.064 12.6 0.2 0.064 12.6 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1565) DUF2235 PF09994.9 CRK31340.1 - 4.2e-68 229.8 0.0 1.2e-67 228.3 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) An_peroxidase PF03098.15 CRK31341.1 - 1.4e-45 155.9 0.0 9.7e-33 113.5 0.0 3.5 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 CRK31341.1 - 0.00036 19.4 0.0 0.0023 16.7 0.0 2.0 2 0 0 2 2 2 1 Cytochrome P450 Glyco_hydro_18 PF00704.28 CRK31342.1 - 1.3e-27 97.4 0.1 1.5e-27 97.2 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Nop53 PF07767.11 CRK31343.1 - 3e-37 129.0 12.4 3.5e-37 128.8 12.4 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) DUF1640 PF07798.11 CRK31345.1 - 0.027 14.5 0.4 0.052 13.6 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) DUF241 PF03087.14 CRK31345.1 - 0.029 14.2 0.5 0.053 13.4 0.5 1.4 1 1 0 1 1 1 0 Arabidopsis protein of unknown function PMEI PF04043.15 CRK31345.1 - 0.037 14.4 0.9 0.11 12.8 0.4 1.9 1 1 0 2 2 2 0 Plant invertase/pectin methylesterase inhibitor SlyX PF04102.12 CRK31345.1 - 0.039 14.6 1.9 20 5.9 0.3 3.7 2 2 1 3 3 3 0 SlyX ApoC-I PF04691.12 CRK31345.1 - 0.049 13.6 1.4 0.55 10.2 0.2 2.8 2 1 1 3 3 3 0 Apolipoprotein C-I (ApoC-1) DUF3130 PF11328.8 CRK31345.1 - 0.05 13.8 0.7 12 6.3 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3130 Baculo_PEP_C PF04513.12 CRK31345.1 - 0.057 13.5 0.2 0.14 12.2 0.2 1.7 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 CRK31345.1 - 0.088 12.9 0.6 0.4 10.7 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF5341 PF17276.2 CRK31345.1 - 0.1 12.8 0.1 0.2 11.8 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5341) FAM184 PF15665.5 CRK31345.1 - 0.15 11.8 5.3 3.7 7.3 5.7 2.2 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B Tup_N PF08581.10 CRK31345.1 - 0.2 12.0 0.1 0.2 12.0 0.1 2.5 3 0 0 3 3 3 0 Tup N-terminal CENP-Q PF13094.6 CRK31345.1 - 0.27 11.4 2.4 0.36 11.0 1.0 1.8 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DHDPS PF00701.22 CRK31346.1 - 2.5e-20 72.4 0.0 2.8e-20 72.2 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DUF1201 PF06716.11 CRK31347.1 - 0.11 12.5 1.4 0.17 11.9 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1201) Glyco_hydro_31 PF01055.26 CRK31349.1 - 2.9e-40 138.8 0.2 3.7e-40 138.5 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 CRK31349.1 - 1.3e-16 60.6 1.4 2.7e-16 59.6 1.4 1.6 1 0 0 1 1 1 1 Galactose mutarotase-like PI3_PI4_kinase PF00454.27 CRK31350.1 - 1.5e-25 90.5 0.0 4.4e-25 88.9 0.0 1.7 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.6 CRK31350.1 - 0.0018 17.7 0.0 0.0025 17.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) AA_permease_2 PF13520.6 CRK31351.1 - 8.9e-36 123.6 16.6 1.1e-35 123.3 16.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CRK31351.1 - 9e-16 57.5 12.1 1.2e-15 57.1 12.1 1.0 1 0 0 1 1 1 1 Amino acid permease AgrD PF05931.11 CRK31351.1 - 0.17 12.0 0.3 0.17 12.0 0.3 2.3 2 0 0 2 2 2 0 Staphylococcal AgrD protein DUF5301 PF17225.3 CRK31352.1 - 0.016 15.6 1.5 0.035 14.5 0.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF5300) Neur_chan_memb PF02932.16 CRK31352.1 - 1.4 8.9 4.6 2.1 8.3 4.6 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3987 PF13148.6 CRK31352.1 - 4.2 6.3 9.3 4.8 6.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Abhydrolase_1 PF00561.20 CRK31353.1 - 2.4e-17 63.4 0.0 6.9e-17 61.9 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CRK31353.1 - 9.2e-11 41.5 0.0 7.4e-09 35.2 0.0 2.5 3 0 0 3 3 3 2 Serine aminopeptidase, S33 Cohesin_load PF10345.9 CRK31354.1 - 3.7e-129 431.9 7.7 5.5e-129 431.3 7.7 1.2 1 0 0 1 1 1 1 Cohesin loading factor Pet127 PF08634.10 CRK31354.1 - 1.2e-113 379.1 1.1 2.2e-113 378.3 1.1 1.4 1 0 0 1 1 1 1 Mitochondrial protein Pet127 Aminotran_5 PF00266.19 CRK31354.1 - 2e-05 23.7 0.0 4.4e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class-V DUF1985 PF09331.11 CRK31354.1 - 0.017 15.1 1.0 0.05 13.6 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1985) TPR_2 PF07719.17 CRK31354.1 - 0.14 12.4 4.9 24 5.3 0.9 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 CRK31354.1 - 2.6 8.8 9.6 52 4.6 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat RRM_1 PF00076.22 CRK31355.1 - 8.4e-33 112.0 0.0 2e-15 56.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CRK31355.1 - 0.00068 19.7 0.0 0.005 16.9 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif RRM_5 PF13893.6 CRK31355.1 - 0.0041 16.7 0.0 0.077 12.6 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 CRK31355.1 - 0.027 14.2 0.9 6.9 6.4 0.2 2.6 2 0 0 2 2 2 0 Ribonuclease B OB domain Nup35_RRM_2 PF14605.6 CRK31355.1 - 0.047 13.7 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Sel1 PF08238.12 CRK31356.1 - 4.4e-09 36.7 3.5 0.001 19.7 0.3 2.6 2 0 0 2 2 2 2 Sel1 repeat zf-CCCH PF00642.24 CRK31359.1 - 9.2e-17 60.5 24.7 1.2e-06 28.3 0.9 4.4 3 1 1 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CRK31359.1 - 1.7e-13 50.2 27.5 1.1e-05 25.2 4.3 4.4 4 0 0 4 4 4 4 Zinc finger domain Torus PF16131.5 CRK31359.1 - 2.7e-10 40.9 20.4 0.0005 20.7 1.2 4.2 1 1 3 4 4 4 4 Torus domain zf-CCCH_4 PF18044.1 CRK31359.1 - 1.7e-05 24.5 1.4 1.7e-05 24.5 1.4 4.3 4 0 0 4 4 4 2 CCCH-type zinc finger GRP PF07172.11 CRK31359.1 - 0.066 13.9 6.3 0.12 13.0 6.3 1.3 1 0 0 1 1 1 0 Glycine rich protein family zf-CCCH_3 PF15663.5 CRK31359.1 - 6.1 7.1 14.4 0.86 9.8 5.7 2.9 1 1 2 3 3 3 0 Zinc-finger containing family Allantoicase PF03561.15 CRK31360.1 - 4.9e-51 172.5 0.1 1.7e-47 161.0 0.0 2.0 2 0 0 2 2 2 2 Allantoicase repeat LEH PF07858.12 CRK31360.1 - 0.16 12.1 0.1 0.25 11.4 0.1 1.2 1 0 0 1 1 1 0 Limonene-1,2-epoxide hydrolase catalytic domain Fungal_trans PF04082.18 CRK31361.1 - 2.2e-10 40.0 0.0 2.6e-10 39.8 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain His_Phos_2 PF00328.22 CRK31362.1 - 0.0012 18.3 0.0 0.0015 18.0 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Peptidase_M13_N PF05649.13 CRK31363.1 - 7e-95 318.9 0.0 9.4e-95 318.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 CRK31363.1 - 3.5e-62 209.7 1.5 5.6e-62 209.0 0.4 1.8 2 0 0 2 2 2 1 Peptidase family M13 adh_short PF00106.25 CRK31364.1 - 7.2e-42 143.0 0.1 9.9e-42 142.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK31364.1 - 2.8e-30 105.6 0.1 4.6e-30 104.9 0.1 1.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 CRK31364.1 - 8.8e-08 31.9 0.0 1.2e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.10 CRK31364.1 - 2.6e-07 30.8 0.1 3.7e-07 30.2 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 CRK31364.1 - 7.6e-06 25.9 0.1 1.8e-05 24.7 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H-binding ADH_zinc_N PF00107.26 CRK31364.1 - 0.0018 18.2 0.1 0.0041 17.1 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NmrA PF05368.13 CRK31364.1 - 0.0023 17.5 0.1 0.0041 16.7 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family peroxidase PF00141.23 CRK31364.1 - 0.0042 16.8 0.0 0.0071 16.1 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Epimerase PF01370.21 CRK31364.1 - 0.0084 15.6 0.2 0.013 15.0 0.2 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 CRK31364.1 - 0.016 15.5 0.1 0.03 14.6 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain RmlD_sub_bind PF04321.17 CRK31364.1 - 0.025 13.7 0.0 0.039 13.0 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain 2-Hacid_dh_C PF02826.19 CRK31364.1 - 0.09 12.1 0.1 0.3 10.4 0.1 1.9 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SAM_decarbox PF01536.16 CRK31366.1 - 3.4e-136 453.9 0.0 4.3e-136 453.6 0.0 1.1 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase Sorting_nexin PF03700.13 CRK31366.1 - 0.14 12.8 1.4 0.26 11.8 1.4 1.4 1 0 0 1 1 1 0 Sorting nexin, N-terminal domain GFO_IDH_MocA PF01408.22 CRK31367.1 - 2.9e-17 63.6 0.1 4.3e-17 63.1 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 CRK31367.1 - 0.024 15.3 0.0 0.049 14.3 0.0 1.6 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Sugar_tr PF00083.24 CRK31368.1 - 1.1e-88 298.1 23.6 1.3e-88 297.8 23.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK31368.1 - 5.1e-37 127.6 52.2 1.1e-26 93.6 28.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CRK31368.1 - 2.3e-07 29.6 0.9 2.3e-07 29.6 0.9 2.8 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF4133 PF13571.6 CRK31368.1 - 9.8 6.6 14.4 2.3 8.6 0.8 3.5 3 1 1 4 4 4 0 Domain of unknown function (DUF4133) ThrE PF06738.12 CRK31369.1 - 2.4e-61 207.2 23.9 1.3e-58 198.3 4.4 2.8 3 0 0 3 3 3 2 Putative threonine/serine exporter ThrE_2 PF12821.7 CRK31369.1 - 1.9e-11 44.2 13.9 1.9e-11 44.2 13.9 2.4 2 0 0 2 2 2 1 Threonine/Serine exporter, ThrE Fungal_trans PF04082.18 CRK31371.1 - 0.0024 17.0 0.1 0.036 13.1 0.0 2.3 2 1 0 2 2 2 2 Fungal specific transcription factor domain MaoC_dehydratas PF01575.19 CRK31379.1 - 4.3e-35 119.9 0.0 6.7e-35 119.3 0.0 1.2 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 CRK31379.1 - 0.0013 18.8 0.0 0.28 11.3 0.0 2.2 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase Zn_clus PF00172.18 CRK31383.1 - 3e-08 33.7 11.9 4.3e-08 33.1 11.9 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.12 CRK31383.1 - 9.1 6.9 12.1 6.1 7.4 2.4 2.2 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region Strep_pep PF14404.6 CRK31386.1 - 0.15 12.4 0.0 0.33 11.2 0.0 1.5 1 0 0 1 1 1 0 Ribosomally synthesized peptide in Streptomyces species His_Phos_1 PF00300.22 CRK31389.1 - 5.6e-22 78.4 0.2 8.9e-22 77.7 0.2 1.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.22 CRK31389.1 - 0.0026 17.2 0.0 0.0034 16.8 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Pil1 PF13805.6 CRK31393.1 - 5.5e-70 235.9 0.4 6.1e-70 235.7 0.4 1.0 1 0 0 1 1 1 1 Eisosome component PIL1 T3SSipB PF16535.5 CRK31393.1 - 0.053 14.0 2.0 0.076 13.5 1.5 1.4 1 1 0 1 1 1 0 Type III cell invasion protein SipB ING PF12998.7 CRK31393.1 - 0.088 13.4 1.2 0.25 12.0 0.6 1.8 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding CDH-cyt PF16010.5 CRK31398.1 - 8.2e-18 64.7 0.0 1.2e-17 64.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DUF2427 PF10348.9 CRK31398.1 - 2.7e-05 23.9 0.6 2.7e-05 23.9 0.6 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) PMP22_Claudin PF00822.20 CRK31398.1 - 0.041 13.8 0.9 0.062 13.2 0.9 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family Cytochrom_B561 PF03188.16 CRK31398.1 - 0.54 10.4 5.9 1.1 9.4 5.9 1.5 1 0 0 1 1 1 0 Eukaryotic cytochrome b561 NAD_binding_5 PF07994.12 CRK31399.1 - 1.3e-145 484.8 0.0 1.5e-145 484.6 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 CRK31399.1 - 1.3e-44 150.9 0.4 2.7e-44 149.9 0.4 1.6 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase DUF5049 PF16468.5 CRK31399.1 - 0.047 13.6 0.0 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5049) DUF3405 PF11885.8 CRK31400.1 - 3.4e-91 306.4 0.6 3.8e-91 306.3 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Ski2_N PF17911.1 CRK31401.1 - 7.4e-41 139.1 0.0 1e-40 138.7 0.0 1.2 1 0 0 1 1 1 1 Ski2 N-terminal region Kinesin PF00225.23 CRK31402.1 - 2.6e-70 237.0 0.9 2.8e-70 236.9 0.9 1.0 1 0 0 1 1 1 1 Kinesin motor domain Borrelia_P83 PF05262.11 CRK31402.1 - 0.0049 15.4 0.3 0.0062 15.1 0.3 1.1 1 0 0 1 1 1 1 Borrelia P83/100 protein Ub-Mut7C PF14451.6 CRK31402.1 - 0.06 13.2 0.1 9.1 6.2 0.0 2.8 2 1 1 3 3 3 0 Mut7-C ubiquitin TEA PF01285.18 CRK31405.1 - 0.11 12.6 0.5 5.5 7.1 0.0 2.5 2 1 0 2 2 2 0 TEA/ATTS domain RNB PF00773.19 CRK31406.1 - 1.7e-38 132.8 0.0 1.9e-38 132.7 0.0 1.0 1 0 0 1 1 1 1 RNB domain AAA_12 PF13087.6 CRK31408.1 - 1.3e-45 155.5 0.0 1.5e-45 155.3 0.0 1.0 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 CRK31408.1 - 0.08 12.7 0.0 0.09 12.5 0.0 1.1 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Pkinase PF00069.25 CRK31411.1 - 3.2e-18 66.0 0.0 5.1e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK31411.1 - 3.9e-15 55.8 0.0 1.1e-14 54.3 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CRK31411.1 - 4.9e-05 22.8 0.0 7.7e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CRK31411.1 - 0.0037 16.6 0.0 0.37 10.1 0.0 2.3 3 0 0 3 3 3 2 Kinase-like APH PF01636.23 CRK31411.1 - 0.0052 16.7 0.9 0.015 15.3 0.9 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family RGS PF00615.19 CRK31412.1 - 2.1e-06 28.0 0.1 0.0085 16.4 0.0 2.6 2 1 0 2 2 2 2 Regulator of G protein signaling domain Pox_A14 PF05767.12 CRK31412.1 - 0.13 12.4 0.1 0.28 11.4 0.1 1.5 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 Fumble PF03630.14 CRK31413.1 - 9.1e-125 416.2 0.0 1.2e-124 415.9 0.0 1.1 1 0 0 1 1 1 1 Fumble Allexi_40kDa PF05549.11 CRK31414.1 - 0.082 12.4 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein RdRP PF05183.12 CRK31418.1 - 2.2e-163 545.1 0.0 4.1e-150 501.2 0.0 2.1 1 1 1 2 2 2 2 RNA dependent RNA polymerase Acetyltransf_1 PF00583.25 CRK31419.1 - 2.3e-15 56.9 0.0 2.9e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CRK31419.1 - 8.8e-14 51.5 0.1 1.2e-13 51.1 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CRK31419.1 - 1.1e-10 41.8 0.1 1.6e-10 41.2 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CRK31419.1 - 8.3e-07 28.9 0.3 8.3e-06 25.7 0.1 2.0 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_3 PF13302.7 CRK31419.1 - 3.3e-06 27.8 0.1 4.2e-06 27.5 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CRK31419.1 - 7.9e-05 22.7 0.0 0.00021 21.4 0.0 1.7 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 CRK31419.1 - 0.00074 19.7 0.1 0.0014 18.7 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 CRK31419.1 - 0.0039 17.3 0.4 0.008 16.3 0.4 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Mrr_cat PF04471.12 CRK31419.1 - 0.033 14.2 0.0 0.051 13.6 0.0 1.4 1 1 0 1 1 1 0 Restriction endonuclease Homeobox_KN PF05920.11 CRK31420.1 - 4.5e-12 45.7 0.2 1e-11 44.5 0.2 1.7 1 0 0 1 1 1 1 Homeobox KN domain Cupin_2 PF07883.11 CRK31420.1 - 1.5e-11 43.8 0.4 9.5e-09 34.9 0.0 2.4 2 0 0 2 2 2 2 Cupin domain Homeodomain PF00046.29 CRK31420.1 - 7.5e-06 25.7 0.1 2.2e-05 24.2 0.1 1.8 1 0 0 1 1 1 1 Homeodomain Cupin_3 PF05899.12 CRK31420.1 - 3.3e-05 23.5 0.2 0.41 10.4 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) HTH_Tnp_Tc5 PF03221.16 CRK31420.1 - 0.00034 20.6 0.1 0.05 13.6 0.1 3.5 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain zf-C2H2_4 PF13894.6 CRK31420.1 - 0.0036 18.0 2.8 0.0036 18.0 2.8 4.7 4 0 0 4 4 4 1 C2H2-type zinc finger AraC_binding PF02311.19 CRK31420.1 - 0.0069 16.3 0.1 0.064 13.2 0.0 2.6 2 0 0 2 2 2 1 AraC-like ligand binding domain Elf1 PF05129.13 CRK31420.1 - 0.033 14.2 1.1 0.4 10.8 1.0 2.4 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zf-C2H2 PF00096.26 CRK31420.1 - 3 8.5 20.3 0.052 14.0 2.5 3.7 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 CRK31420.1 - 5.7 7.6 7.7 7.8 7.2 0.5 2.6 2 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats FAD_binding_4 PF01565.23 CRK31423.1 - 2.3e-35 121.4 0.0 3.9e-35 120.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain SepSecS PF05889.13 CRK31423.1 - 0.027 13.2 0.0 0.041 12.6 0.0 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS ANF_receptor PF01094.28 CRK31423.1 - 0.032 13.4 0.0 0.048 12.8 0.0 1.2 1 0 0 1 1 1 0 Receptor family ligand binding region Acetyltransf_1 PF00583.25 CRK31424.1 - 9.3e-15 54.9 0.0 1.1e-14 54.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CRK31424.1 - 8.3e-14 51.6 0.2 1.2e-13 51.2 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CRK31424.1 - 9.9e-10 38.7 0.0 1.4e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CRK31424.1 - 3.6e-07 30.1 0.4 8.5e-06 25.6 0.1 2.1 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_3 PF13302.7 CRK31424.1 - 1.4e-06 29.1 0.0 1.7e-06 28.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CRK31424.1 - 4.1e-05 23.6 0.3 0.0001 22.3 0.1 1.8 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 CRK31424.1 - 0.0014 18.8 0.0 0.0026 17.9 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain RAB3GAP2_N PF14655.6 CRK31424.1 - 0.0059 15.9 0.1 0.0084 15.4 0.1 1.4 1 1 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Acetyltransf_6 PF13480.7 CRK31424.1 - 0.0071 16.5 0.1 0.0091 16.2 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FMN_bind_2 PF04299.12 CRK31425.1 - 1.7e-60 203.5 0.1 2e-60 203.3 0.1 1.0 1 0 0 1 1 1 1 Putative FMN-binding domain Homeobox_KN PF05920.11 CRK31426.1 - 8e-13 48.1 0.1 1.7e-12 47.0 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain Cupin_2 PF07883.11 CRK31426.1 - 2.3e-09 36.8 0.0 5.2e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Homeodomain PF00046.29 CRK31426.1 - 4.7e-06 26.4 0.1 1.1e-05 25.2 0.1 1.6 1 0 0 1 1 1 1 Homeodomain APH PF01636.23 CRK31426.1 - 7.3e-06 26.1 0.0 1.6e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family zf-C2H2_4 PF13894.6 CRK31426.1 - 0.0097 16.7 2.8 0.0097 16.7 2.8 4.6 4 0 0 4 4 4 1 C2H2-type zinc finger Elf1 PF05129.13 CRK31426.1 - 0.024 14.6 1.3 0.22 11.6 1.2 2.3 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like AraC_binding PF02311.19 CRK31426.1 - 0.025 14.5 0.1 0.24 11.3 0.0 2.4 2 0 0 2 2 2 0 AraC-like ligand binding domain Sugar_tr PF00083.24 CRK31427.1 - 2.2e-65 221.3 28.7 2.5e-65 221.1 28.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK31427.1 - 4e-16 58.9 32.4 4e-16 58.9 32.4 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily FAD_binding_3 PF01494.19 CRK31428.1 - 1.8e-21 76.8 0.0 2e-20 73.4 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 CRK31428.1 - 7.2e-11 42.3 1.1 0.00049 19.8 1.2 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CRK31428.1 - 1.4e-09 37.6 0.2 3.2e-05 23.3 0.1 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CRK31428.1 - 5.1e-07 29.1 0.5 8.4e-07 28.4 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 CRK31428.1 - 1.9e-06 26.9 0.3 9.8e-05 21.2 0.2 2.1 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 CRK31428.1 - 7.5e-06 26.1 0.5 3e-05 24.2 0.3 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 CRK31428.1 - 0.0001 21.6 0.0 0.00046 19.4 0.2 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.27 CRK31428.1 - 0.00035 21.1 0.1 0.0058 17.2 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CRK31428.1 - 0.0005 19.2 0.1 0.0011 18.0 0.1 1.5 1 1 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.7 CRK31428.1 - 0.0013 18.2 0.3 0.0019 17.6 0.3 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase SE PF08491.10 CRK31428.1 - 0.0014 17.8 0.0 0.01 14.9 0.0 2.0 2 0 0 2 2 2 1 Squalene epoxidase Amino_oxidase PF01593.24 CRK31428.1 - 0.0017 17.7 0.2 1.4 8.1 0.0 2.5 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Thi4 PF01946.17 CRK31428.1 - 0.0018 17.5 0.2 0.0031 16.8 0.2 1.3 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.14 CRK31428.1 - 0.029 13.2 0.2 0.06 12.2 0.1 1.5 1 1 0 1 1 1 0 Tryptophan halogenase 3HCDH_N PF02737.18 CRK31428.1 - 0.03 14.2 0.0 0.054 13.4 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 CRK31428.1 - 0.077 12.3 0.1 0.14 11.4 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain APH PF01636.23 CRK31430.1 - 0.00015 21.8 1.5 0.00015 21.8 1.5 2.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family FAA_hydrolase PF01557.18 CRK31431.1 - 4.2e-55 186.8 0.0 5.5e-55 186.4 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF3500 PF12006.8 CRK31432.1 - 4.3e-108 361.3 0.0 6.2e-108 360.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) Glyco_hydro_3_C PF01915.22 CRK31432.1 - 2.2e-51 174.7 0.0 3.4e-51 174.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 CRK31432.1 - 3e-40 138.6 0.0 7e-40 137.4 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 CRK31432.1 - 2.8e-24 85.0 0.3 6.9e-24 83.8 0.3 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 CRK31432.1 - 2.4e-05 24.2 0.0 4.8e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 PA14 domain DUF11 PF01345.18 CRK31432.1 - 0.028 14.7 0.3 0.12 12.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF11 DUF3237 PF11578.8 CRK31432.1 - 0.1 12.5 0.1 0.48 10.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3237) BAT PF15915.5 CRK31432.1 - 0.12 12.2 1.1 0.42 10.5 1.1 1.9 1 1 0 1 1 1 0 GAF and HTH_10 associated domain Ribosomal_S4e PF00900.20 CRK31433.1 - 3.2e-36 123.1 0.4 5.3e-36 122.4 0.1 1.5 2 0 0 2 2 2 1 Ribosomal family S4e RS4NT PF08071.12 CRK31433.1 - 7.6e-18 64.3 4.0 1.2e-17 63.7 4.0 1.4 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 CRK31433.1 - 6.2e-07 29.0 0.0 1.3e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 S4 domain Sipho_tail PF05709.11 CRK31433.1 - 0.14 11.5 0.0 0.43 9.9 0.0 1.6 1 1 1 2 2 2 0 Phage tail protein ANAPC4_WD40 PF12894.7 CRK31434.1 - 8.7e-18 64.4 4.8 3.1e-05 24.2 0.3 4.3 2 1 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CRK31434.1 - 7.2e-17 61.5 18.8 0.00033 21.4 0.1 6.4 7 0 0 7 7 7 5 WD domain, G-beta repeat Ge1_WD40 PF16529.5 CRK31434.1 - 1.9e-06 27.1 0.1 0.00031 19.8 0.0 3.3 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 CRK31434.1 - 2e-06 27.8 0.2 0.00034 20.6 0.1 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Aldedh PF00171.22 CRK31435.1 - 6.2e-129 430.5 3.9 7.5e-129 430.2 3.9 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family BetaGal_dom3 PF13363.6 CRK31439.1 - 0.00035 20.1 0.0 3.8 7.1 0.0 3.2 3 0 0 3 3 3 3 Beta-galactosidase, domain 3 Mg_trans_NIPA PF05653.14 CRK31443.1 - 1e-61 208.7 6.4 8.3e-59 199.1 4.5 2.0 2 0 0 2 2 2 2 Magnesium transporter NIPA SLC35F PF06027.12 CRK31443.1 - 0.018 14.5 4.6 1.7 8.1 0.8 2.5 3 0 0 3 3 3 0 Solute carrier family 35 TssN PF17555.2 CRK31443.1 - 0.93 8.8 6.2 1.6 8.1 6.2 1.4 1 0 0 1 1 1 0 Type VI secretion system, TssN DUF1461 PF07314.11 CRK31443.1 - 2.6 7.9 5.4 0.81 9.6 1.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1461) DUF373 PF04123.13 CRK31443.1 - 4.6 6.6 7.1 7.4 5.9 6.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF373) RRM_1 PF00076.22 CRK31444.1 - 7.5e-72 237.1 0.0 7.3e-17 61.0 0.0 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 CRK31444.1 - 6.7e-06 26.0 0.4 1.8 8.4 0.0 3.8 3 0 0 3 3 3 3 Rrp7 RRM-like N-terminal domain RRM_7 PF16367.5 CRK31444.1 - 1.2e-05 25.4 0.0 29 4.8 0.0 5.2 5 0 0 5 5 5 0 RNA recognition motif RNase_II_C_S1 PF18614.1 CRK31444.1 - 8.6e-05 22.4 0.2 0.82 9.7 0.1 2.7 3 0 0 3 3 3 2 RNase II-type exonuclease C-terminal S1 domain RL PF17797.1 CRK31444.1 - 0.028 14.3 0.0 13 5.8 0.0 2.5 2 0 0 2 2 2 0 RL domain Nup35_RRM_2 PF14605.6 CRK31444.1 - 0.029 14.4 0.0 9 6.4 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif DbpA PF03880.15 CRK31444.1 - 0.085 12.9 0.2 14 5.8 0.0 3.4 4 0 0 4 4 4 0 DbpA RNA binding domain Cnd3 PF12719.7 CRK31445.1 - 2.5e-92 309.2 2.3 2.5e-92 309.2 2.3 2.5 4 0 0 4 4 4 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 CRK31445.1 - 5e-16 58.9 20.8 6.1e-05 23.3 1.5 6.5 6 0 0 6 6 6 4 HEAT repeats HEAT PF02985.22 CRK31445.1 - 8.2e-12 44.3 19.4 0.12 12.7 0.0 10.7 11 0 0 11 11 11 2 HEAT repeat Cnd1 PF12717.7 CRK31445.1 - 1e-06 28.9 3.5 0.64 10.1 0.0 6.4 6 0 0 6 6 6 2 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 CRK31445.1 - 0.031 14.5 0.6 20 5.4 0.0 4.0 3 1 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 FANCI_HD1 PF14679.6 CRK31445.1 - 0.076 13.0 0.2 0.79 9.7 0.0 2.9 2 0 0 2 2 2 0 FANCI helical domain 1 LytTR PF04397.15 CRK31445.1 - 0.14 12.4 0.2 85 3.5 0.0 3.8 4 0 0 4 4 4 0 LytTr DNA-binding domain TetR_C_25 PF17933.1 CRK31445.1 - 0.14 12.5 0.1 21 5.5 0.0 2.8 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain HEAT_EZ PF13513.6 CRK31445.1 - 0.71 10.5 17.3 4 8.0 0.3 6.4 6 2 2 8 8 8 0 HEAT-like repeat Phosphodiest PF01663.22 CRK31446.1 - 2.9e-10 40.3 0.1 5e-10 39.5 0.1 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 CRK31446.1 - 0.0034 16.8 0.1 0.0054 16.1 0.1 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 CRK31446.1 - 0.0062 16.0 0.0 0.0096 15.3 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Cnd3 PF12719.7 CRK31447.1 - 5.3e-13 48.8 0.0 6.8e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 Nuclear condensing complex subunits, C-term domain Phosphodiest PF01663.22 CRK31448.1 - 1.2e-13 51.4 1.0 4.3e-10 39.7 0.2 2.3 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 CRK31448.1 - 0.00073 19.0 0.0 0.0012 18.3 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 CRK31448.1 - 0.0031 16.9 0.0 0.0054 16.2 0.0 1.3 1 0 0 1 1 1 1 Sulfatase DUF2423 PF10338.9 CRK31449.1 - 2.7e-20 72.3 3.8 2.7e-20 72.3 3.8 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) TonB_N PF16031.5 CRK31449.1 - 0.005 17.3 2.7 0.0063 17.0 2.7 1.2 1 0 0 1 1 1 1 TonB polyproline region TRAPP PF04051.16 CRK31450.1 - 3.5e-46 156.6 0.0 5.6e-46 155.9 0.0 1.3 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component PINIT PF14324.6 CRK31450.1 - 2.5e-45 154.4 0.1 3.9e-45 153.8 0.1 1.3 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 CRK31450.1 - 6.5e-22 77.0 6.1 1.4e-21 76.0 6.1 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 CRK31450.1 - 9.3e-06 25.4 1.5 2e-05 24.3 1.5 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.27 CRK31450.1 - 0.0018 18.0 0.0 0.0045 16.7 0.0 1.6 1 0 0 1 1 1 1 SAP domain zf-Sec23_Sec24 PF04810.15 CRK31450.1 - 0.023 14.7 0.8 0.069 13.2 0.8 1.8 1 1 0 1 1 1 0 Sec23/Sec24 zinc finger FYVE_2 PF02318.16 CRK31450.1 - 0.086 13.1 0.9 0.16 12.2 0.9 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger Prok-RING_4 PF14447.6 CRK31450.1 - 0.16 11.8 1.2 0.41 10.5 1.2 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 CRK31450.1 - 1.9 8.7 4.9 4.5 7.5 4.9 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Ldh_1_C PF02866.18 CRK31451.1 - 2.9e-48 164.0 0.0 4.2e-48 163.4 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 CRK31451.1 - 1.6e-44 151.4 0.1 2.5e-44 150.8 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 CRK31451.1 - 0.0053 15.8 0.0 0.0075 15.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 CRK31451.1 - 0.14 12.0 0.0 0.32 10.9 0.0 1.7 1 1 0 1 1 1 0 NAD(P)H-binding Ribosomal_L28e PF01778.17 CRK31452.1 - 2.7e-31 108.7 1.9 4e-31 108.2 1.9 1.2 1 0 0 1 1 1 1 Ribosomal L28e protein family Ustilago_mating PF05722.12 CRK31452.1 - 0.053 13.0 5.3 0.04 13.5 4.2 1.4 1 1 0 1 1 1 0 Ustilago B locus mating-type protein DUF2015 PF09435.10 CRK31453.1 - 2.9e-47 159.2 0.0 3.3e-47 159.0 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) FixS PF03597.15 CRK31453.1 - 0.74 9.6 3.0 1.2 8.9 3.0 1.3 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type DUF3242 PF11586.8 CRK31456.1 - 0.35 10.6 0.8 0.53 10.0 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3242) Glyco_hydro_47 PF01532.20 CRK31457.1 - 4.3e-50 170.9 0.0 1.4e-40 139.6 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 47 YbhQ PF11076.8 CRK31459.1 - 0.0016 18.5 6.7 0.6 10.1 0.0 3.2 3 0 0 3 3 3 2 Putative inner membrane protein YbhQ NPCC PF08058.11 CRK31459.1 - 0.0046 17.0 0.0 6.6 6.8 0.0 3.0 2 0 0 2 2 2 2 Nuclear pore complex component Phage_holin_3_7 PF05449.11 CRK31459.1 - 0.005 16.8 11.1 0.32 11.0 0.7 3.6 3 0 0 3 3 3 2 Putative 3TM holin, Phage_holin_3 SARAF PF06682.12 CRK31459.1 - 0.16 11.6 0.1 19 4.8 0.0 2.2 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Dimer_Tnp_hAT PF05699.14 CRK31459.1 - 0.26 11.1 7.8 6.4 6.6 0.4 3.5 5 0 0 5 5 5 0 hAT family C-terminal dimerisation region TPPK_C PF12555.8 CRK31459.1 - 0.94 9.6 12.9 1.8 8.7 0.5 3.4 3 0 0 3 3 3 0 Thiamine pyrophosphokinase C terminal ADH_N PF08240.12 CRK31460.1 - 5.6e-26 90.6 3.4 1e-25 89.7 3.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CRK31460.1 - 1.8e-16 60.3 0.0 2.8e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 CRK31460.1 - 2.3e-05 24.0 0.4 0.0029 17.1 0.2 2.4 2 1 0 2 2 2 2 Glucose dehydrogenase C-terminus ATP-synt_G PF04718.15 CRK31462.1 - 5.4e-14 52.8 0.7 1.3e-13 51.7 0.2 1.8 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit Alanine_zipper PF11839.8 CRK31462.1 - 2.5 8.5 11.5 1.4 9.3 3.1 2.4 2 0 0 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein ADH_N PF08240.12 CRK31463.1 - 6.1e-16 58.3 2.4 9.9e-16 57.6 2.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CRK31463.1 - 7e-08 32.5 0.0 1.1e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ATP-synt_G PF04718.15 CRK31464.1 - 3e-33 114.6 3.9 3.4e-33 114.4 1.7 2.2 2 1 0 2 2 2 1 Mitochondrial ATP synthase g subunit DUF2477 PF10631.9 CRK31464.1 - 0.19 12.4 4.7 0.12 13.1 1.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2477) ATP-synt_B PF00430.18 CRK31464.1 - 2.8 8.0 10.7 1.1 9.4 1.2 2.2 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) Alanine_zipper PF11839.8 CRK31464.1 - 3.9 7.9 22.2 5.5 7.4 4.0 2.4 2 0 0 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein Methyltransf_23 PF13489.6 CRK31465.1 - 2.4e-29 102.3 0.0 4.6e-14 52.6 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 CRK31465.1 - 4.4e-21 75.4 0.0 3.6e-09 37.2 0.0 3.0 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 CRK31465.1 - 4.2e-18 65.8 0.0 8.5e-08 32.8 0.0 3.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 CRK31465.1 - 1.1e-14 54.5 0.0 5.7e-06 26.2 0.0 3.5 2 2 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.18 CRK31465.1 - 9.4e-12 44.8 0.0 0.00013 21.4 0.0 3.3 2 2 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 CRK31465.1 - 3.9e-09 37.1 0.2 0.0044 17.7 0.0 4.0 3 2 0 3 3 3 2 Methyltransferase domain FtsJ PF01728.19 CRK31465.1 - 6.2e-09 36.2 0.0 0.0036 17.4 0.0 2.3 2 0 0 2 2 2 2 FtsJ-like methyltransferase Methyltransf_8 PF05148.15 CRK31465.1 - 0.0002 21.3 0.0 1.1 9.0 0.0 3.6 4 0 0 4 4 4 2 Hypothetical methyltransferase PrmA PF06325.13 CRK31465.1 - 0.00067 19.1 0.0 1.4 8.2 0.0 2.4 2 0 0 2 2 2 2 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 CRK31465.1 - 0.0077 16.0 0.0 4.5 7.0 0.0 2.3 2 0 0 2 2 2 2 Lysine methyltransferase MTS PF05175.14 CRK31465.1 - 0.012 15.2 0.0 6.9 6.2 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase small domain PCMT PF01135.19 CRK31465.1 - 0.049 13.4 0.0 20 4.9 0.0 3.2 3 1 0 3 3 3 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 CRK31465.1 - 0.069 12.7 0.0 16 5.1 0.0 2.4 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW Rap1_C PF11626.8 CRK31465.1 - 0.14 12.2 0.0 0.7 10.0 0.0 2.1 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain TFIIA PF03153.13 CRK31467.1 - 1.7e-95 321.4 30.3 2.1e-95 321.2 30.3 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF1876 PF08962.11 CRK31467.1 - 0.68 9.9 3.8 12 6.0 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1876) Hamartin PF04388.12 CRK31467.1 - 1.4 7.5 11.3 1.8 7.2 11.3 1.1 1 0 0 1 1 1 0 Hamartin protein Pex14_N PF04695.13 CRK31467.1 - 1.8 9.2 37.5 1.6 9.4 16.7 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Maf PF02545.14 CRK31468.1 - 2.7e-44 150.9 0.0 3.6e-44 150.5 0.0 1.2 1 0 0 1 1 1 1 Maf-like protein tRNA-synt_2b PF00587.25 CRK31468.1 - 2.3e-21 76.6 0.0 4e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Glyco_hydro_47 PF01532.20 CRK31469.1 - 3.4e-169 563.6 0.0 4e-169 563.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Utp11 PF03998.13 CRK31470.1 - 2e-51 175.3 12.8 2.5e-51 175.0 12.8 1.0 1 0 0 1 1 1 1 Utp11 protein Cwf_Cwc_15 PF04889.12 CRK31470.1 - 0.16 11.7 14.8 0.034 13.9 9.9 1.9 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein GCIP PF13324.6 CRK31470.1 - 3.7 7.1 10.5 0.72 9.4 7.0 1.5 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting AlaDh_PNT_N PF05222.15 CRK31472.1 - 1.3e-23 83.7 0.0 2e-23 83.2 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 CRK31472.1 - 2.1e-06 27.2 0.0 8.3e-06 25.2 0.0 1.8 1 1 1 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Cmc1 PF08583.10 CRK31473.1 - 1.1e-12 47.7 0.1 1.1e-12 47.7 0.1 2.0 3 0 0 3 3 3 1 Cytochrome c oxidase biogenesis protein Cmc1 like fn3 PF00041.21 CRK31474.1 - 1.1e-08 35.3 0.0 3.1e-08 33.9 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III domain Stevor PF17410.2 CRK31474.1 - 0.0074 15.9 14.3 0.013 15.1 14.3 1.3 1 0 0 1 1 1 1 Subtelomeric Variable Open Reading frame HLH PF00010.26 CRK31475.1 - 4.2e-09 36.2 0.0 6.3e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Umbravirus_LDM PF04817.12 CRK31475.1 - 0.025 13.9 0.8 0.029 13.8 0.8 1.1 1 0 0 1 1 1 0 Umbravirus long distance movement (LDM) family Utp11 PF03998.13 CRK31476.1 - 1.1e-40 140.1 7.4 1.1e-40 140.1 7.4 2.7 2 0 0 2 2 2 1 Utp11 protein AlaDh_PNT_N PF05222.15 CRK31476.1 - 1.1e-21 77.5 0.0 3.5e-21 75.9 0.0 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain fn3 PF00041.21 CRK31476.1 - 1.7e-08 34.7 0.0 4.4e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III domain AlaDh_PNT_C PF01262.21 CRK31476.1 - 0.00022 20.6 0.0 0.00056 19.3 0.0 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Stevor PF17410.2 CRK31476.1 - 0.011 15.4 14.3 0.019 14.5 14.3 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame DUF4407 PF14362.6 CRK31476.1 - 5 6.4 34.2 10 5.4 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) Cmc1 PF08583.10 CRK31478.1 - 1.1e-16 60.6 0.2 1.1e-16 60.6 0.2 1.9 3 0 0 3 3 3 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.13 CRK31478.1 - 0.056 13.6 0.6 7.5 6.8 0.1 2.3 2 0 0 2 2 2 0 CHCH domain Glyco_tranf_2_3 PF13641.6 CRK31480.1 - 1.9e-22 80.3 0.0 2.5e-22 79.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 CRK31480.1 - 1.2e-06 28.5 0.0 4e-06 26.7 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 CRK31480.1 - 9.3e-05 22.0 0.0 0.00027 20.5 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 21 RdgC PF04381.12 CRK31480.1 - 0.11 11.8 0.2 0.19 10.9 0.2 1.3 1 0 0 1 1 1 0 Putative exonuclease, RdgC Glyco_tranf_2_3 PF13641.6 CRK31481.1 - 1.3e-22 80.8 0.0 1.7e-22 80.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 CRK31481.1 - 3.5e-06 27.0 0.0 1.2e-05 25.2 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 CRK31481.1 - 0.0001 21.8 0.0 0.00027 20.5 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 21 RdgC PF04381.12 CRK31481.1 - 0.12 11.6 0.2 0.19 10.9 0.2 1.2 1 0 0 1 1 1 0 Putative exonuclease, RdgC DUF4818 PF16089.5 CRK31483.1 - 0.0002 21.8 0.8 0.0007 20.0 0.0 2.0 2 1 0 2 2 2 1 Domain of unknown function (DUF4818) GWT1 PF06423.12 CRK31486.1 - 1.4e-43 148.6 2.5 2.5e-43 147.8 0.3 2.2 2 0 0 2 2 2 1 GWT1 DUF4818 PF16089.5 CRK31486.1 - 0.0027 18.2 0.0 0.0027 18.2 0.0 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4818) Pkinase PF00069.25 CRK31487.1 - 1e-47 162.8 0.0 6e-43 147.1 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CRK31487.1 - 7e-31 107.4 0.0 1.2e-30 106.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase GWT1 PF06423.12 CRK31487.1 - 1.1e-11 45.1 0.1 2.1e-11 44.2 0.1 1.4 1 0 0 1 1 1 1 GWT1 Kinase-like PF14531.6 CRK31487.1 - 0.00011 21.6 0.0 0.00019 20.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CRK31487.1 - 0.00029 20.9 0.0 0.00059 19.8 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CRK31487.1 - 0.015 14.3 0.1 0.023 13.7 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 CRK31487.1 - 0.017 14.5 0.1 0.027 13.8 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CRK31487.1 - 0.02 14.5 0.0 0.041 13.5 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.25 CRK31488.1 - 1.9e-64 217.6 0.0 3.5e-64 216.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK31488.1 - 3.9e-36 124.7 0.0 1.9e-30 106.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CRK31488.1 - 8.6e-08 31.8 0.0 0.0002 20.8 0.0 2.3 1 1 1 2 2 2 2 Kinase-like APH PF01636.23 CRK31488.1 - 0.00031 20.7 0.0 0.00059 19.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CRK31488.1 - 0.016 14.1 0.2 0.026 13.5 0.2 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 CRK31488.1 - 0.02 14.3 0.1 0.033 13.6 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CRK31488.1 - 0.022 14.4 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 RIO1 family AA_permease PF00324.21 CRK31489.1 - 2.8e-107 359.3 37.3 3.4e-107 359.0 37.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CRK31489.1 - 3.6e-28 98.6 40.3 4.4e-28 98.3 40.3 1.0 1 0 0 1 1 1 1 Amino acid permease INTS5_N PF14837.6 CRK31489.1 - 0.11 12.1 0.4 0.18 11.4 0.4 1.2 1 0 0 1 1 1 0 Integrator complex subunit 5 N-terminus OPT PF03169.15 CRK31491.1 - 2.1e-112 376.8 48.5 2.4e-112 376.6 48.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein WD40 PF00400.32 CRK31492.1 - 1e-11 45.2 15.4 5e-05 24.0 0.2 7.6 8 0 0 8 8 7 2 WD domain, G-beta repeat NACHT PF05729.12 CRK31492.1 - 3.3e-11 43.4 0.0 1.8e-10 41.0 0.0 2.2 2 0 0 2 2 2 1 NACHT domain ANAPC4_WD40 PF12894.7 CRK31492.1 - 5e-07 29.9 0.1 3.6 8.0 0.0 6.6 3 2 4 8 8 7 1 Anaphase-promoting complex subunit 4 WD40 domain AAA_16 PF13191.6 CRK31492.1 - 5.7e-06 26.8 0.0 1.7e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Nup160 PF11715.8 CRK31492.1 - 9.3e-05 21.3 11.1 0.48 9.0 0.1 5.4 2 2 4 6 6 6 2 Nucleoporin Nup120/160 PQQ_2 PF13360.6 CRK31492.1 - 0.00025 20.7 0.1 0.0042 16.7 0.0 2.8 3 0 0 3 3 3 1 PQQ-like domain DUF676 PF05057.14 CRK31492.1 - 0.001 18.6 0.0 0.0018 17.8 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Nucleoporin_N PF08801.11 CRK31492.1 - 0.0013 17.5 0.3 1.8 7.2 0.0 3.8 4 1 0 4 4 4 1 Nup133 N terminal like Vps16_N PF04841.13 CRK31492.1 - 0.0016 17.3 0.0 0.012 14.3 0.0 2.1 2 0 0 2 2 2 1 Vps16, N-terminal region Ge1_WD40 PF16529.5 CRK31492.1 - 0.003 16.6 1.2 1.2 8.0 0.0 3.5 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein RNA_helicase PF00910.22 CRK31492.1 - 0.0043 17.4 0.1 0.012 16.0 0.0 1.9 2 0 0 2 2 1 1 RNA helicase AAA_33 PF13671.6 CRK31492.1 - 0.0081 16.3 0.0 0.024 14.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 CRK31492.1 - 0.012 16.1 0.0 0.029 14.8 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.20 CRK31492.1 - 0.03 14.2 0.0 0.062 13.2 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_22 PF13401.6 CRK31492.1 - 0.036 14.4 0.0 0.13 12.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain Lipase_3 PF01764.25 CRK31492.1 - 0.04 13.8 0.0 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) PQQ_3 PF13570.6 CRK31492.1 - 0.04 14.4 0.6 35 5.1 0.0 4.2 4 0 0 4 4 3 0 PQQ-like domain AAA_25 PF13481.6 CRK31492.1 - 0.047 13.3 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CRK31492.1 - 0.057 13.1 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 CRK31492.1 - 0.059 12.5 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Hira PF07569.11 CRK31492.1 - 0.076 12.7 0.2 20 4.8 0.0 3.7 4 0 0 4 4 4 0 TUP1-like enhancer of split Hydrolase_4 PF12146.8 CRK31492.1 - 0.076 12.3 0.1 0.47 9.7 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF499 PF04465.12 CRK31492.1 - 0.14 9.9 0.0 0.2 9.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF499) Abhydrolase_6 PF12697.7 CRK31492.1 - 0.14 12.7 0.0 0.44 11.1 0.0 1.9 1 0 0 1 1 1 0 Alpha/beta hydrolase family NTPase_1 PF03266.15 CRK31492.1 - 0.17 11.8 0.0 0.47 10.3 0.0 1.8 1 0 0 1 1 1 0 NTPase Thioesterase PF00975.20 CRK31492.1 - 0.17 12.0 0.2 0.5 10.4 0.0 1.8 2 0 0 2 2 2 0 Thioesterase domain Dus PF01207.17 CRK31493.1 - 2.8e-40 138.3 0.1 3.6e-29 101.8 0.0 2.7 3 0 0 3 3 3 2 Dihydrouridine synthase (Dus) zf_CCCH_4 PF18345.1 CRK31493.1 - 0.21 11.7 0.6 0.41 10.8 0.6 1.5 1 0 0 1 1 1 0 Zinc finger domain Etmic-2 PF06670.11 CRK31493.1 - 0.3 10.0 4.3 0.49 9.3 4.3 1.2 1 0 0 1 1 1 0 Microneme protein Etmic-2 FAD_binding_3 PF01494.19 CRK31496.1 - 1.2e-74 251.7 0.0 2.5e-74 250.6 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 CRK31496.1 - 0.0014 17.9 0.0 0.0034 16.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CRK31496.1 - 0.0018 18.8 0.0 0.0043 17.6 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CRK31496.1 - 0.01 15.4 0.1 0.32 10.5 0.0 2.7 3 0 0 3 3 3 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CRK31496.1 - 0.023 14.9 0.0 0.062 13.5 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain UDPG_MGDP_dh_N PF03721.14 CRK31496.1 - 0.04 13.5 0.0 0.066 12.8 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.14 CRK31496.1 - 0.057 12.1 0.0 0.099 11.3 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein XdhC_C PF13478.6 CRK31496.1 - 0.07 13.6 0.0 0.19 12.3 0.0 1.8 1 0 0 1 1 1 0 XdhC Rossmann domain MoaF PF10703.9 CRK31496.1 - 0.1 12.5 1.0 0.47 10.4 0.0 2.4 3 0 0 3 3 3 0 MoaF N-terminal domain Thi4 PF01946.17 CRK31496.1 - 0.11 11.7 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 Thi4 family RGS12_us1 PF16613.5 CRK31497.1 - 0.0062 16.8 0.2 0.022 15.1 0.2 1.9 1 0 0 1 1 1 1 Unstructured region of RGS12 Kelch_4 PF13418.6 CRK31499.1 - 7e-06 25.9 9.0 1.6e-05 24.8 0.1 4.7 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_3 PF13415.6 CRK31499.1 - 0.28 11.5 2.3 42 4.6 0.0 4.1 4 0 0 4 4 4 0 Galactose oxidase, central domain Kelch_6 PF13964.6 CRK31499.1 - 2.5 8.5 4.7 47 4.5 0.0 4.0 4 0 0 4 4 4 0 Kelch motif ANAPC4_WD40 PF12894.7 CRK31500.1 - 0.0018 18.5 0.0 0.13 12.5 0.0 2.9 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CRK31500.1 - 0.0055 17.5 0.0 1.5 9.8 0.0 3.3 3 0 0 3 3 3 1 WD domain, G-beta repeat DDHD PF02862.17 CRK31501.1 - 4.1e-22 79.4 0.1 1.8e-12 47.9 0.0 3.0 2 1 0 3 3 3 2 DDHD domain Abhydrolase_6 PF12697.7 CRK31501.1 - 0.051 14.2 0.1 0.051 14.2 0.1 2.3 2 1 0 2 2 2 0 Alpha/beta hydrolase family Fungal_trans PF04082.18 CRK31502.1 - 0.00095 18.3 0.1 0.0013 17.9 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain HET PF06985.11 CRK31505.1 - 5.4e-05 23.6 0.3 0.00013 22.3 0.3 1.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short_C2 PF13561.6 CRK31510.1 - 7e-27 94.5 0.1 1.1e-26 93.9 0.1 1.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRK31510.1 - 8.3e-13 48.2 0.2 1.2e-12 47.7 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Fcf1 PF04900.12 CRK31516.1 - 5.1e-20 71.7 0.1 9e-20 70.9 0.1 1.4 1 0 0 1 1 1 1 Fcf1 CDC45 PF02724.14 CRK31516.1 - 0.11 10.8 8.4 0.11 10.8 8.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Pkinase PF00069.25 CRK31524.1 - 3.5e-08 33.1 0.0 5.8e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK31524.1 - 0.0013 18.1 0.0 0.002 17.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CRK31524.1 - 0.004 16.5 0.0 0.0068 15.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CRK31524.1 - 0.035 14.0 0.0 0.074 13.0 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ank_4 PF13637.6 CRK31525.1 - 1.1e-22 80.0 1.9 8e-09 35.9 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 CRK31525.1 - 2.4e-22 79.3 0.2 4.5e-10 40.0 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 CRK31525.1 - 7e-20 70.5 0.4 6.9e-07 29.4 0.1 6.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 CRK31525.1 - 3.7e-18 65.3 3.5 7.1e-10 38.9 0.1 4.6 4 1 2 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CRK31525.1 - 5.1e-17 60.2 0.9 0.0013 19.1 0.0 6.9 6 0 0 6 6 6 4 Ankyrin repeat NACHT PF05729.12 CRK31525.1 - 2.6e-06 27.5 0.0 2.3e-05 24.4 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 CRK31525.1 - 3.5e-05 24.1 0.0 0.00013 22.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain DinB PF05163.12 CRK31525.1 - 0.0071 16.3 0.5 1.9 8.4 0.0 3.4 3 0 0 3 3 3 1 DinB family RE_LlaJI PF09563.10 CRK31525.1 - 0.16 11.1 0.0 1.3 8.1 0.0 2.2 2 0 0 2 2 2 0 LlaJI restriction endonuclease DUF2981 PF11200.8 CRK31527.1 - 0.01 15.6 0.2 0.01 15.6 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) TrbM PF07424.11 CRK31528.1 - 0.037 14.0 0.2 0.071 13.1 0.2 1.4 1 0 0 1 1 1 0 TrbM DUF2267 PF10025.9 CRK31529.1 - 0.013 15.8 0.2 0.023 15.0 0.2 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) Baculo_PEP_C PF04513.12 CRK31529.1 - 0.056 13.5 0.2 0.1 12.6 0.2 1.5 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus PilJ PF13675.6 CRK31529.1 - 0.1 12.7 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Coprogen_oxidas PF01218.18 CRK31530.1 - 1.1e-96 323.1 1.7 1.2e-96 323.0 1.7 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Aminotran_3 PF00202.21 CRK31532.1 - 5.5e-20 71.4 0.0 6.8e-20 71.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III CUE PF02845.16 CRK31533.1 - 3.9e-06 26.5 0.0 5.3e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 CUE domain FoP_duplication PF13865.6 CRK31533.1 - 0.16 12.5 9.0 0.22 12.1 9.0 1.2 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Cation_ATPase PF13246.6 CRK31534.1 - 0.084 13.0 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 Cation transport ATPase (P-type) Aldedh PF00171.22 CRK31539.1 - 1.1e-39 136.3 0.4 1.2e-39 136.2 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Glyco_transf_15 PF01793.16 CRK31541.1 - 5.6e-105 351.2 12.5 6.3e-105 351.0 12.5 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase AA_permease PF00324.21 CRK31542.1 - 4.4e-36 124.5 15.8 5.6e-36 124.2 15.8 1.1 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 CRK31542.1 - 3.2e-24 85.7 0.1 5.9e-10 38.7 0.0 3.2 3 0 0 3 3 3 3 Solute carrier family 12 WD40 PF00400.32 CRK31542.1 - 7.9e-14 51.8 0.0 0.0078 17.0 0.0 3.9 3 0 0 3 3 3 3 WD domain, G-beta repeat AA_permease_2 PF13520.6 CRK31542.1 - 3.1e-11 42.8 17.5 4.9e-11 42.1 17.5 1.2 1 0 0 1 1 1 1 Amino acid permease MTS PF05175.14 CRK31542.1 - 8.2e-06 25.5 0.0 2.1e-05 24.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 CRK31542.1 - 0.00069 19.4 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK31542.1 - 0.006 17.3 0.0 0.015 16.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 CRK31542.1 - 0.0071 15.8 0.0 0.019 14.4 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) PrmC_N PF17827.1 CRK31542.1 - 0.008 16.8 0.6 0.043 14.4 0.4 2.4 2 1 0 2 2 2 1 PrmC N-terminal domain Blt1_C PF17183.4 CRK31542.1 - 0.079 12.6 0.6 0.21 11.2 0.6 1.6 1 0 0 1 1 1 0 Get5 carboxyl domain SMI1_KNR4 PF09346.10 CRK31544.1 - 4.4e-31 108.0 0.0 8.1e-31 107.2 0.0 1.5 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) Aa_trans PF01490.18 CRK31544.1 - 2.1e-22 79.4 4.6 2.7e-22 79.1 4.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein FixH PF05751.11 CRK31544.1 - 1.4 8.9 3.9 1.3 9.0 2.4 1.6 2 0 0 2 2 2 0 FixH FHA PF00498.26 CRK31545.1 - 3.7e-10 40.0 0.2 5.5e-10 39.5 0.2 1.3 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CRK31545.1 - 0.0016 18.7 0.0 0.0025 18.1 0.0 1.3 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Alpha_adaptinC2 PF02883.20 CRK31545.1 - 0.11 12.8 0.0 0.32 11.3 0.0 1.9 1 1 0 1 1 1 0 Adaptin C-terminal domain MscS_porin PF12795.7 CRK31551.1 - 1.6e-05 24.6 31.8 6.4e-05 22.6 19.2 2.1 1 1 1 2 2 2 1 Mechanosensitive ion channel porin domain Filament PF00038.21 CRK31551.1 - 2.3e-05 24.1 24.7 0.0013 18.4 7.2 2.0 1 1 1 2 2 2 2 Intermediate filament protein DUF4201 PF13870.6 CRK31551.1 - 8e-05 22.4 21.7 0.0045 16.8 10.8 2.6 1 1 1 2 2 2 2 Domain of unknown function (DUF4201) THOC7 PF05615.13 CRK31551.1 - 0.00023 21.4 24.7 0.017 15.4 6.0 2.2 2 0 0 2 2 2 2 Tho complex subunit 7 GAS PF13851.6 CRK31551.1 - 0.00052 19.4 25.3 0.04 13.3 12.0 2.6 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding WEMBL PF05701.11 CRK31551.1 - 0.00053 18.8 22.1 0.00065 18.5 22.1 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light ATG16 PF08614.11 CRK31551.1 - 0.00089 19.5 32.5 0.013 15.7 22.6 2.5 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 CRK31551.1 - 0.001 19.1 29.3 0.024 14.6 12.0 2.4 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myosin_tail_1 PF01576.19 CRK31551.1 - 0.0011 16.9 29.0 0.0012 16.7 29.0 1.0 1 0 0 1 1 1 1 Myosin tail DivIC PF04977.15 CRK31551.1 - 0.0015 18.3 25.5 0.11 12.3 0.9 4.1 1 1 3 4 4 4 1 Septum formation initiator Seryl_tRNA_N PF02403.22 CRK31551.1 - 0.0015 18.7 18.7 0.014 15.6 2.3 3.1 1 1 2 3 3 3 1 Seryl-tRNA synthetase N-terminal domain Fez1 PF06818.15 CRK31551.1 - 0.0016 18.9 26.2 0.11 12.9 6.1 2.0 1 1 1 2 2 2 2 Fez1 BRE1 PF08647.11 CRK31551.1 - 0.0016 18.5 22.8 0.025 14.7 5.9 2.5 1 1 1 2 2 2 2 BRE1 E3 ubiquitin ligase HOOK PF05622.12 CRK31551.1 - 0.0022 16.3 24.8 0.0026 16.0 24.8 1.1 1 0 0 1 1 1 1 HOOK protein TPR_MLP1_2 PF07926.12 CRK31551.1 - 0.0022 18.1 31.1 0.012 15.7 12.2 3.0 1 1 2 3 3 3 2 TPR/MLP1/MLP2-like protein ADIP PF11559.8 CRK31551.1 - 0.003 17.7 24.7 0.054 13.6 15.5 2.3 1 1 1 2 2 2 1 Afadin- and alpha -actinin-Binding HMMR_N PF15905.5 CRK31551.1 - 0.0032 17.0 24.9 0.011 15.2 12.0 2.0 1 1 1 2 2 2 1 Hyaluronan mediated motility receptor N-terminal Spc7 PF08317.11 CRK31551.1 - 0.0035 16.3 26.3 0.14 11.0 18.3 2.2 1 1 1 2 2 2 2 Spc7 kinetochore protein TMF_TATA_bd PF12325.8 CRK31551.1 - 0.0041 17.3 27.4 0.06 13.6 3.6 3.4 1 1 1 3 3 3 1 TATA element modulatory factor 1 TATA binding APG6_N PF17675.1 CRK31551.1 - 0.0058 17.2 35.0 0.16 12.5 10.2 2.7 1 1 1 2 2 2 1 Apg6 coiled-coil region Lebercilin PF15619.6 CRK31551.1 - 0.0065 16.2 28.3 0.017 14.8 10.8 2.4 1 1 1 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease BLOC1_2 PF10046.9 CRK31551.1 - 0.0068 16.7 5.1 0.0068 16.7 5.1 2.5 2 1 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_13 PF13166.6 CRK31551.1 - 0.0088 14.7 13.2 0.018 13.7 13.2 1.5 1 1 0 1 1 1 1 AAA domain DUF3450 PF11932.8 CRK31551.1 - 0.011 15.0 26.9 0.013 14.8 9.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) HIP1_clath_bdg PF16515.5 CRK31551.1 - 0.012 16.2 28.8 0.13 12.8 14.2 3.1 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 PRKG1_interact PF15898.5 CRK31551.1 - 0.022 15.7 10.9 0.022 15.7 10.9 3.1 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain DUF4763 PF15960.5 CRK31551.1 - 0.023 14.0 21.1 0.034 13.5 21.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) Cep57_CLD PF14073.6 CRK31551.1 - 0.023 14.7 26.8 0.71 9.9 19.7 2.0 1 1 1 2 2 2 0 Centrosome localisation domain of Cep57 BST2 PF16716.5 CRK31551.1 - 0.024 15.2 25.5 0.29 11.8 9.0 3.1 1 1 2 3 3 3 0 Bone marrow stromal antigen 2 CENP-H PF05837.12 CRK31551.1 - 0.027 14.9 24.8 0.058 13.8 8.3 2.1 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DUF4530 PF15039.6 CRK31551.1 - 0.031 14.4 0.9 0.031 14.4 0.9 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4530) T4bSS_IcmS PF12608.8 CRK31551.1 - 0.031 14.6 2.4 0.035 14.4 1.4 1.6 2 0 0 2 2 1 0 Type IVb secretion, IcmS, effector-recruitment DUF1664 PF07889.12 CRK31551.1 - 0.034 14.2 12.3 0.95 9.5 2.5 2.9 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) CEP63 PF17045.5 CRK31551.1 - 0.038 13.9 22.2 0.06 13.2 22.2 1.3 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa Laminin_II PF06009.12 CRK31551.1 - 0.039 14.0 15.2 0.18 11.8 4.0 2.5 1 1 1 2 2 2 0 Laminin Domain II FlaC_arch PF05377.11 CRK31551.1 - 0.039 14.3 16.8 1.1 9.7 2.9 4.1 2 2 2 4 4 4 0 Flagella accessory protein C (FlaC) Phage_HK97_TLTM PF06120.11 CRK31551.1 - 0.052 12.7 12.1 0.11 11.7 0.5 2.1 1 1 1 2 2 2 0 Tail length tape measure protein DUF4407 PF14362.6 CRK31551.1 - 0.056 12.8 20.2 0.11 11.9 20.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Vps5 PF09325.10 CRK31551.1 - 0.057 13.0 13.0 0.54 9.8 3.6 2.4 1 1 0 2 2 2 0 Vps5 C terminal like DHR10 PF18595.1 CRK31551.1 - 0.057 13.5 30.6 0.73 9.9 10.3 2.8 1 1 0 2 2 2 0 Designed helical repeat protein 10 domain EzrA PF06160.12 CRK31551.1 - 0.058 11.6 19.3 0.18 9.9 19.3 1.7 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA YabA PF06156.13 CRK31551.1 - 0.058 14.0 17.6 0.062 13.9 3.8 2.4 1 1 1 2 2 2 0 Initiation control protein YabA IFT57 PF10498.9 CRK31551.1 - 0.073 12.0 17.8 0.62 9.0 3.0 2.1 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 CLZ PF16526.5 CRK31551.1 - 0.083 13.3 25.2 0.69 10.3 0.8 3.8 1 1 3 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FlxA PF14282.6 CRK31551.1 - 0.083 12.9 21.3 0.63 10.1 5.2 2.9 1 1 1 2 2 2 0 FlxA-like protein Csm1_N PF18504.1 CRK31551.1 - 0.084 13.2 24.5 0.23 11.8 5.5 3.6 1 1 1 3 3 3 0 Csm1 N-terminal domain COG2 PF06148.11 CRK31551.1 - 0.095 12.8 16.0 1 9.5 5.4 2.9 1 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 FAM76 PF16046.5 CRK31551.1 - 0.14 11.5 16.4 0.22 10.8 15.4 1.6 1 1 0 1 1 1 0 FAM76 protein DUF2730 PF10805.8 CRK31551.1 - 0.16 12.0 13.1 0.98 9.5 3.7 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2730) Mod_r PF07200.13 CRK31551.1 - 0.17 12.0 23.7 0.39 10.8 14.0 2.8 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF2203 PF09969.9 CRK31551.1 - 0.21 12.3 16.6 5.5 7.7 10.9 3.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Wtap PF17098.5 CRK31551.1 - 0.22 11.5 22.1 6 6.8 2.3 4.0 1 1 1 3 3 3 0 WTAP/Mum2p family MCPsignal PF00015.21 CRK31551.1 - 0.3 10.9 7.9 2.9 7.7 0.8 2.1 1 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain NPV_P10 PF05531.12 CRK31551.1 - 0.32 11.5 10.1 2.1 8.9 1.7 3.1 2 2 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF641 PF04859.12 CRK31551.1 - 0.37 11.1 18.8 0.27 11.6 5.0 2.3 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) WXG100 PF06013.12 CRK31551.1 - 0.42 10.9 15.6 4 7.8 5.4 4.1 1 1 2 3 3 3 0 Proteins of 100 residues with WXG kleA_kleC PF17383.2 CRK31551.1 - 0.47 10.8 16.2 2 8.8 3.1 3.2 2 1 1 3 3 3 0 Uncharacterized KorC regulated protein A DUF724 PF05266.14 CRK31551.1 - 0.52 10.1 19.3 0.7 9.7 4.9 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF724) Laminin_I PF06008.14 CRK31551.1 - 0.55 9.9 22.2 0.46 10.2 11.8 2.4 1 1 1 2 2 2 0 Laminin Domain I KASH_CCD PF14662.6 CRK31551.1 - 0.59 9.9 28.7 34 4.2 28.7 2.3 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Prefoldin PF02996.17 CRK31551.1 - 0.6 10.0 19.9 3.6 7.5 1.3 4.0 1 1 4 5 5 5 0 Prefoldin subunit Nup54 PF13874.6 CRK31551.1 - 0.62 10.2 20.3 0.036 14.2 11.8 2.1 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Tropomyosin PF00261.20 CRK31551.1 - 0.64 9.3 28.5 0.29 10.5 11.6 2.5 1 1 2 3 3 3 0 Tropomyosin Occludin_ELL PF07303.13 CRK31551.1 - 0.65 10.8 14.0 0.93 10.3 4.4 2.8 1 1 0 2 2 2 0 Occludin homology domain Tropomyosin_1 PF12718.7 CRK31551.1 - 0.65 10.1 27.9 1.6 8.9 7.4 2.3 1 1 0 2 2 2 0 Tropomyosin like Golgin_A5 PF09787.9 CRK31551.1 - 0.66 9.4 27.9 2.7 7.4 17.1 2.1 1 1 1 2 2 2 0 Golgin subfamily A member 5 DUF948 PF06103.11 CRK31551.1 - 0.74 10.1 10.1 15 5.9 1.8 3.5 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) GP57 PF17594.2 CRK31551.1 - 0.75 9.6 5.8 1.3 8.8 0.8 2.3 2 0 0 2 2 2 0 Phage Tail fiber assembly helper gene product 57 Exonuc_VII_L PF02601.15 CRK31551.1 - 0.77 9.3 18.4 7.5 6.0 18.4 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit ERM PF00769.19 CRK31551.1 - 0.8 9.5 33.8 2.5 7.8 0.7 2.5 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Uds1 PF15456.6 CRK31551.1 - 0.85 9.8 23.4 0.48 10.6 2.6 3.3 1 1 2 3 3 3 0 Up-regulated During Septation Prefoldin_2 PF01920.20 CRK31551.1 - 0.85 9.6 25.5 0.71 9.8 5.0 4.0 2 2 2 4 4 4 0 Prefoldin subunit Fib_alpha PF08702.10 CRK31551.1 - 0.98 9.6 13.8 2.8 8.1 7.4 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family V_ATPase_I PF01496.19 CRK31551.1 - 1.1 7.1 13.1 3 5.7 13.1 1.6 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family ING PF12998.7 CRK31551.1 - 1.1 9.8 10.5 0.62 10.7 6.3 2.4 1 1 2 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding Sec34 PF04136.15 CRK31551.1 - 1.1 9.1 16.2 3 7.7 1.8 3.2 1 1 1 3 3 3 0 Sec34-like family Bacillus_HBL PF05791.11 CRK31551.1 - 1.2 8.9 11.9 0.79 9.5 2.4 2.2 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) USP8_interact PF08941.10 CRK31551.1 - 1.3 8.8 13.6 2.5 7.9 1.9 2.9 1 1 2 3 3 3 0 USP8 interacting DUF812 PF05667.11 CRK31551.1 - 1.3 7.8 23.1 2.5 6.9 23.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF812) TraF_2 PF13729.6 CRK31551.1 - 1.3 8.3 7.4 0.69 9.2 0.6 2.1 1 1 1 2 2 2 0 F plasmid transfer operon, TraF, protein Tup_N PF08581.10 CRK31551.1 - 1.5 9.2 18.1 0.78 10.1 2.7 3.0 2 1 1 3 3 3 0 Tup N-terminal DUF16 PF01519.16 CRK31551.1 - 1.5 9.4 14.7 3.8 8.0 4.9 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 Cnn_1N PF07989.11 CRK31551.1 - 1.6 9.0 20.4 1.7 8.8 3.1 3.8 1 1 2 3 3 3 0 Centrosomin N-terminal motif 1 DUF3584 PF12128.8 CRK31551.1 - 1.6 6.1 26.0 0.65 7.4 12.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) COMM_domain PF07258.14 CRK31551.1 - 1.9 8.6 8.6 3 8.0 1.8 3.3 2 2 1 3 3 2 0 COMM domain Nup88 PF10168.9 CRK31551.1 - 2 6.1 16.8 3.6 5.3 16.8 1.4 1 1 0 1 1 1 0 Nuclear pore component Lectin_N PF03954.14 CRK31551.1 - 2.1 8.1 14.4 1.5 8.5 0.9 2.8 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain ZapB PF06005.12 CRK31551.1 - 2.1 8.9 28.9 0.3 11.6 7.6 3.1 1 1 2 3 3 3 0 Cell division protein ZapB OmpH PF03938.14 CRK31551.1 - 2.1 8.7 23.7 33 4.8 0.9 2.9 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) CorA PF01544.18 CRK31551.1 - 2.1 7.6 15.6 3.6 6.8 11.2 2.4 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein DUF745 PF05335.13 CRK31551.1 - 2.1 8.0 17.4 2.2 7.9 13.3 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF745) bZIP_1 PF00170.21 CRK31551.1 - 2.2 8.5 17.7 3.9 7.6 6.6 3.3 2 2 0 2 2 2 0 bZIP transcription factor SHE3 PF17078.5 CRK31551.1 - 2.2 8.0 21.9 0.62 9.7 10.7 2.3 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 DUF3138 PF11336.8 CRK31551.1 - 2.5 6.6 4.3 8.6 4.8 4.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) Atg14 PF10186.9 CRK31551.1 - 2.5 7.1 22.4 5.3 6.0 9.3 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4200 PF13863.6 CRK31551.1 - 2.8 8.4 22.9 1.3e+03 -0.2 21.8 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) 3-PAP PF12578.8 CRK31551.1 - 2.8 7.7 7.9 0.55 10.0 0.3 3.2 2 2 1 4 4 3 0 Myotubularin-associated protein DUF4140 PF13600.6 CRK31551.1 - 2.9 8.4 27.9 79 3.8 9.3 4.0 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) GrpE PF01025.19 CRK31551.1 - 3 7.5 20.5 5.6 6.6 5.7 2.9 1 1 1 2 2 2 0 GrpE XhlA PF10779.9 CRK31551.1 - 3.3 8.0 12.3 2.9 8.2 0.8 3.1 2 1 1 3 3 3 0 Haemolysin XhlA Cep57_CLD_2 PF14197.6 CRK31551.1 - 3.3 7.9 35.5 1.1 9.4 11.3 4.2 2 2 0 3 3 3 0 Centrosome localisation domain of PPC89 YlqD PF11068.8 CRK31551.1 - 3.4 8.0 20.3 4.6 7.6 2.2 3.0 1 1 2 3 3 3 0 YlqD protein HAUS-augmin3 PF14932.6 CRK31551.1 - 3.9 7.0 27.1 3 7.3 13.6 2.5 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 FliD_N PF02465.18 CRK31551.1 - 4.2 8.1 12.4 1.5e+02 3.2 8.0 3.1 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF4337 PF14235.6 CRK31551.1 - 4.6 7.3 14.6 2.4e+03 -1.5 14.6 2.2 1 1 0 1 1 0 0 Domain of unknown function (DUF4337) TMF_DNA_bd PF12329.8 CRK31551.1 - 4.8 7.3 29.3 2 8.5 3.2 3.9 2 2 2 4 4 4 0 TATA element modulatory factor 1 DNA binding Phlebovirus_NSM PF07246.11 CRK31551.1 - 4.8 6.5 10.3 10 5.4 9.6 1.7 1 1 0 1 1 1 0 Phlebovirus nonstructural protein NS-M SOGA PF11365.8 CRK31551.1 - 4.9 8.4 22.9 4.2 8.6 3.7 3.1 1 1 2 3 3 3 0 Protein SOGA FPP PF05911.11 CRK31551.1 - 5 5.2 26.3 4.6 5.3 6.8 2.0 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil betaPIX_CC PF16523.5 CRK31551.1 - 5 7.0 17.2 1.8 8.5 2.7 2.9 2 2 0 2 2 2 0 betaPIX coiled coil FapA PF03961.13 CRK31551.1 - 5 5.6 16.5 3.8 6.0 8.4 2.1 1 1 1 2 2 2 0 Flagellar Assembly Protein A TMPIT PF07851.13 CRK31551.1 - 6 6.0 15.9 6.1e+02 -0.6 15.8 2.2 1 1 0 1 1 1 0 TMPIT-like protein DivIVA PF05103.13 CRK31551.1 - 6.4 6.9 18.2 73 3.4 0.9 3.0 1 1 1 2 2 2 0 DivIVA protein DUF2381 PF09544.10 CRK31551.1 - 7.1 6.1 18.8 0.86 9.1 6.0 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF2381) Plk4_PB2 PF18409.1 CRK31551.1 - 7.3 7.3 8.8 8.5 7.1 2.1 2.2 1 1 1 2 2 2 0 Polo-like Kinase 4 Polo Box 2 CENP-O PF09496.10 CRK31551.1 - 7.5 6.5 10.9 12 5.8 10.8 1.4 1 1 0 1 1 1 0 Cenp-O kinetochore centromere component Rootletin PF15035.6 CRK31551.1 - 7.8 6.5 27.3 1.7 8.6 14.8 2.4 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion HAUS5 PF14817.6 CRK31551.1 - 8.2 5.1 23.5 65 2.1 23.5 2.1 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 5 Macoilin PF09726.9 CRK31551.1 - 8.3 4.8 20.5 3.7 6.0 13.1 1.9 1 1 1 2 2 2 0 Macoilin family Cation_ATPase_C PF00689.21 CRK31552.1 - 1e-14 54.7 0.1 1.3e-14 54.3 0.1 1.1 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase_3 PF08282.12 CRK31552.1 - 2e-05 24.5 1.0 2.4e-05 24.2 1.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CRK31552.1 - 0.12 12.6 0.3 0.22 11.8 0.3 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase FAD_binding_3 PF01494.19 CRK31555.1 - 1.1e-25 90.6 0.0 1.9e-25 89.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 CRK31555.1 - 5.5e-08 32.4 1.5 0.00027 20.3 0.9 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CRK31555.1 - 7.2e-08 32.4 5.3 0.00028 20.6 4.4 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CRK31555.1 - 6e-06 26.4 4.8 6e-05 23.2 1.0 3.2 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CRK31555.1 - 4e-05 22.9 2.1 7.3e-05 22.0 2.1 1.4 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 CRK31555.1 - 8e-05 21.8 0.8 0.00026 20.2 0.8 1.8 1 1 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.14 CRK31555.1 - 0.00025 20.0 1.6 0.23 10.3 0.9 2.4 1 1 1 2 2 2 2 Tryptophan halogenase Thi4 PF01946.17 CRK31555.1 - 0.0038 16.5 0.5 0.0069 15.6 0.5 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 CRK31555.1 - 0.0063 15.3 2.4 0.027 13.2 0.6 2.2 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.6 CRK31555.1 - 0.011 15.7 1.3 0.018 15.0 0.1 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding CENP-F_leu_zip PF10473.9 CRK31555.1 - 0.015 15.4 7.9 0.026 14.6 7.9 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Pyr_redox PF00070.27 CRK31555.1 - 0.016 15.7 4.8 0.038 14.5 2.6 2.8 4 0 0 4 4 3 0 Pyridine nucleotide-disulphide oxidoreductase Spc7 PF08317.11 CRK31555.1 - 0.023 13.6 8.0 0.034 13.0 8.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein SE PF08491.10 CRK31555.1 - 0.06 12.4 0.0 0.097 11.7 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase GIDA PF01134.22 CRK31555.1 - 0.062 12.4 1.2 0.091 11.8 0.6 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A DHR10 PF18595.1 CRK31555.1 - 0.066 13.3 8.7 0.15 12.1 8.7 1.5 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Pyr_redox_3 PF13738.6 CRK31555.1 - 0.13 11.4 4.8 0.041 13.1 1.4 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CRK31555.1 - 0.16 11.3 1.7 0.49 9.7 1.7 1.8 1 0 0 1 1 1 0 FAD dependent oxidoreductase TRAF_BIRC3_bd PF16673.5 CRK31555.1 - 3.3 7.6 8.3 29 4.6 0.1 2.8 3 0 0 3 3 2 0 TNF receptor-associated factor BIRC3 binding domain HR1 PF02185.16 CRK31555.1 - 6 7.1 11.2 0.18 11.9 3.0 2.6 2 1 1 3 3 3 0 Hr1 repeat Aldedh PF00171.22 CRK31556.1 - 1.6e-127 425.8 0.0 2.1e-127 425.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Cyclase PF04199.13 CRK31556.1 - 2.8e-05 24.4 0.0 5.5e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Putative cyclase DUF2188 PF09954.9 CRK31556.1 - 0.027 14.6 0.0 0.099 12.8 0.0 2.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2188) AMP-binding PF00501.28 CRK31558.1 - 3e-74 250.1 0.0 3.7e-74 249.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CRK31558.1 - 4.2e-13 50.1 0.0 8.9e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Epimerase PF01370.21 CRK31559.1 - 0.00068 19.2 0.0 0.0019 17.7 0.0 1.7 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 CRK31559.1 - 0.0023 17.2 0.0 0.91 8.6 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 CRK31559.1 - 0.012 15.6 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H-binding MFS_1 PF07690.16 CRK31560.1 - 1.1e-26 93.6 23.9 3.9e-26 91.8 23.9 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily DER1 PF04511.15 CRK31562.1 - 1.8e-07 31.3 0.8 2.2e-07 31.0 0.8 1.1 1 0 0 1 1 1 1 Der1-like family MMS1_N PF10433.9 CRK31565.1 - 4.7e-47 160.7 0.0 6.2e-47 160.3 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term ANAPC4_WD40 PF12894.7 CRK31565.1 - 0.0047 17.2 0.0 1.4 9.2 0.0 2.3 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain HisKA PF00512.25 CRK31568.1 - 8.3e-19 67.4 0.6 8.3e-19 67.4 0.6 2.2 2 1 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 CRK31568.1 - 3.4e-06 27.4 0.1 3.2e-05 24.3 0.0 2.1 2 0 0 2 2 2 1 GAF domain GAF PF01590.26 CRK31568.1 - 8.5e-06 26.4 0.0 1.3e-05 25.8 0.0 1.3 1 0 0 1 1 1 1 GAF domain DUF2514 PF10721.9 CRK31568.1 - 0.0022 18.1 4.2 0.0028 17.7 4.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2514) GAF_3 PF13492.6 CRK31568.1 - 0.0033 17.8 0.0 0.0075 16.6 0.0 1.6 1 0 0 1 1 1 1 GAF domain PIEZO PF15917.5 CRK31568.1 - 0.13 11.7 1.6 0.17 11.3 1.6 1.1 1 0 0 1 1 1 0 Piezo ABC2_membrane_3 PF12698.7 CRK31570.1 - 2e-13 50.2 21.7 2.5e-13 49.9 21.7 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF4202 PF13875.6 CRK31570.1 - 0.25 11.2 0.0 0.34 10.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4202) Ras PF00071.22 CRK31571.1 - 1.6e-43 148.1 0.0 4.3e-43 146.7 0.0 1.6 1 1 0 1 1 1 1 Ras family Roc PF08477.13 CRK31571.1 - 8.8e-19 67.9 0.0 2.1e-17 63.5 0.0 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CRK31571.1 - 0.00035 20.1 0.0 0.0026 17.3 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CRK31571.1 - 0.014 14.9 0.1 0.44 10.0 0.1 2.7 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Abhydrolase_4 PF08386.10 CRK31571.1 - 0.016 15.3 0.0 0.039 14.1 0.0 1.6 2 0 0 2 2 2 0 TAP-like protein AAA_16 PF13191.6 CRK31571.1 - 0.027 14.8 0.0 0.038 14.4 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.10 CRK31571.1 - 0.045 13.2 0.0 0.92 8.9 0.0 2.0 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_25 PF13481.6 CRK31571.1 - 0.047 13.3 0.2 0.19 11.3 0.1 1.9 1 1 1 2 2 2 0 AAA domain CbiA PF01656.23 CRK31571.1 - 0.084 12.9 0.0 0.3 11.2 0.0 1.8 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Septin PF00735.18 CRK31571.1 - 0.097 11.9 0.0 0.24 10.6 0.0 1.6 2 0 0 2 2 2 0 Septin DUF1638 PF07796.11 CRK31572.1 - 0.12 12.4 0.0 0.17 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1638) Mtf2_C PF14061.6 CRK31574.1 - 0.055 13.6 0.1 0.13 12.4 0.1 1.6 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 FAD_binding_4 PF01565.23 CRK31575.1 - 1.1e-25 90.0 0.0 1.5e-25 89.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Peripla_BP_6 PF13458.6 CRK31575.1 - 0.057 13.1 0.0 0.078 12.6 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein Abhydrolase_1 PF00561.20 CRK31577.1 - 3.6e-12 46.5 0.4 5e-12 46.0 0.2 1.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CRK31577.1 - 2.5e-11 43.3 0.4 3.1e-11 43.0 0.4 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CRK31577.1 - 1.5e-09 38.8 1.7 1.8e-09 38.5 1.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 CRK31577.1 - 0.0043 17.2 0.1 0.0061 16.7 0.1 1.2 1 0 0 1 1 1 1 Thioesterase domain Peptidase_S15 PF02129.18 CRK31577.1 - 0.073 12.7 0.3 0.2 11.2 0.3 1.7 1 1 1 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Glyco_transf_64 PF09258.10 CRK31579.1 - 4.1e-42 144.1 0.0 4.4e-42 144.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Glycos_transf_2 PF00535.26 CRK31579.1 - 0.0097 15.7 0.2 0.054 13.3 0.2 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 2 Dynamin_N PF00350.23 CRK31581.1 - 3.6e-15 56.4 0.0 4.1e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 Dynamin family AnfO_nitrog PF09582.10 CRK31582.1 - 0.048 13.0 0.0 0.078 12.3 0.0 1.3 1 0 0 1 1 1 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) Pkinase PF00069.25 CRK31583.1 - 1.5e-68 231.0 0.0 1.7e-68 230.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK31583.1 - 3e-37 128.3 0.0 3.8e-37 128.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CRK31583.1 - 5.2e-07 29.3 0.0 1.2e-06 28.1 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 CRK31583.1 - 0.001 19.0 0.0 0.065 13.1 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CRK31583.1 - 0.0017 17.2 0.0 0.0025 16.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 CRK31583.1 - 0.012 14.7 0.0 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 CRK31583.1 - 0.05 12.5 0.0 0.067 12.1 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 CRK31583.1 - 0.1 12.0 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 CRK31583.1 - 0.19 11.3 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Homeodomain PF00046.29 CRK31584.1 - 7.7e-13 48.1 3.4 2e-12 46.8 3.4 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CRK31584.1 - 0.0016 18.3 0.4 0.0047 16.8 0.4 1.8 1 0 0 1 1 1 1 Homeobox KN domain ADIP PF11559.8 CRK31584.1 - 6.2 6.9 12.2 10 6.2 2.1 1.9 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding HAD_2 PF13419.6 CRK31585.1 - 1.9e-17 63.9 0.0 2.9e-16 60.0 0.0 2.0 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CRK31585.1 - 2.2e-11 44.5 0.0 8.7e-11 42.5 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CRK31585.1 - 0.0024 18.3 0.2 0.028 14.8 0.2 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase GHL6 PF14871.6 CRK31585.1 - 0.019 15.1 0.1 0.051 13.7 0.0 1.7 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase 6 Hydrolase_6 PF13344.6 CRK31585.1 - 0.062 13.4 0.0 5.9 7.1 0.0 2.8 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase GN3L_Grn1 PF08701.11 CRK31586.1 - 2.6e-24 85.1 17.0 4.9e-24 84.2 17.0 1.4 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 CRK31586.1 - 9.8e-17 61.1 0.2 6.3e-13 48.8 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CRK31586.1 - 1.4e-07 31.6 0.1 8e-06 25.9 0.1 2.3 1 1 0 1 1 1 1 RsgA GTPase GTP_EFTU PF00009.27 CRK31586.1 - 7.4e-06 25.6 0.0 0.0082 15.7 0.0 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 CRK31586.1 - 8.7e-06 25.9 6.9 0.025 14.6 0.1 3.7 3 1 1 4 4 4 2 Dynamin family FeoB_N PF02421.18 CRK31586.1 - 6.6e-05 22.5 0.1 0.0031 17.1 0.1 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_16 PF13191.6 CRK31586.1 - 0.0053 17.1 0.7 1.1 9.6 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain Nuc_deoxyri_tr2 PF15891.5 CRK31586.1 - 0.008 16.5 0.1 0.083 13.2 0.0 2.3 2 0 0 2 2 2 1 Nucleoside 2-deoxyribosyltransferase like MeaB PF03308.16 CRK31586.1 - 0.054 12.5 2.9 0.06 12.3 0.0 2.4 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Torsin PF06309.11 CRK31586.1 - 0.078 13.1 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Torsin Roc PF08477.13 CRK31586.1 - 0.092 13.0 0.0 21 5.4 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 CRK31586.1 - 0.092 12.1 0.0 0.29 10.4 0.0 1.8 2 0 0 2 2 2 0 AIG1 family IIGP PF05049.13 CRK31586.1 - 0.17 10.9 0.3 1.7 7.6 0.0 2.0 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) RNB PF00773.19 CRK31587.1 - 3.7e-95 319.0 0.1 5e-95 318.6 0.1 1.2 1 0 0 1 1 1 1 RNB domain Rrp44_S1 PF17215.3 CRK31587.1 - 1.2e-30 105.3 0.1 4e-30 103.6 0.1 2.0 1 0 0 1 1 1 1 S1 domain OB_Dis3 PF17849.1 CRK31587.1 - 1.3e-20 73.2 0.0 3.3e-20 71.9 0.0 1.8 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 CRK31587.1 - 2.1e-09 37.8 0.0 6.2e-09 36.2 0.0 1.9 1 0 0 1 1 1 1 PIN domain Rrp44_CSD1 PF17216.3 CRK31587.1 - 2.9e-05 23.8 0.3 8.3e-05 22.3 0.3 1.7 1 1 0 1 1 1 1 Rrp44-like cold shock domain CSD2 PF17876.1 CRK31587.1 - 8.1e-05 22.7 0.1 0.00081 19.5 0.0 2.7 3 0 0 3 3 3 1 Cold shock domain Dis3l2_C_term PF17877.1 CRK31587.1 - 0.035 14.4 0.0 0.12 12.7 0.0 1.9 1 0 0 1 1 1 0 DIS3-like exonuclease 2 C terminal TcfC PF16967.5 CRK31587.1 - 0.07 12.6 0.0 0.52 9.8 0.0 2.3 2 0 0 2 2 2 0 E-set like domain D123 PF07065.14 CRK31588.1 - 2.6e-82 276.4 0.0 2.9e-82 276.3 0.0 1.0 1 0 0 1 1 1 1 D123 Dak1 PF02733.17 CRK31596.1 - 2.4e-63 213.9 8.8 2.7e-63 213.8 8.8 1.0 1 0 0 1 1 1 1 Dak1 domain ER_lumen_recept PF00810.18 CRK31599.1 - 4.9e-14 53.4 0.4 4.9e-14 53.4 0.4 1.4 2 0 0 2 2 2 1 ER lumen protein retaining receptor UDPGP PF01704.18 CRK31603.1 - 1.2e-86 291.0 0.0 1.3e-86 290.9 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Sugar_tr PF00083.24 CRK31607.1 - 1.1e-25 90.4 12.0 1.4e-25 90.1 12.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter TMEM132D_C PF15706.5 CRK31607.1 - 1 9.2 0.0 1 9.2 0.0 2.1 2 1 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term FA_desaturase PF00487.24 CRK31607.1 - 2.5 7.9 6.8 0.35 10.7 0.3 1.9 1 1 1 2 2 2 0 Fatty acid desaturase RAMA PF18755.1 CRK31611.1 - 0.0023 18.3 0.1 0.016 15.6 0.0 2.5 2 0 0 2 2 2 1 Restriction Enzyme Adenine Methylase Associated Zn_clus PF00172.18 CRK31611.1 - 0.058 13.5 6.4 0.11 12.7 6.4 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_2 PF07719.17 CRK31615.1 - 7.1e-05 22.6 0.1 0.00013 21.8 0.1 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 CRK31615.1 - 0.00068 19.7 0.0 0.0013 18.8 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 CRK31615.1 - 0.002 18.7 0.0 0.0032 18.1 0.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 CRK31615.1 - 0.0037 17.7 0.0 0.006 17.1 0.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 CRK31615.1 - 0.012 15.9 0.0 0.018 15.3 0.0 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 CRK31615.1 - 0.016 15.9 0.7 0.084 13.7 1.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 CRK31615.1 - 0.018 15.6 3.3 0.066 13.9 3.3 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 CRK31615.1 - 0.027 14.3 0.0 0.047 13.5 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_9 PF13371.6 CRK31615.1 - 0.056 13.6 0.3 0.39 10.9 0.6 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat ADH_zinc_N_2 PF13602.6 CRK31617.1 - 3.9e-28 99.2 0.1 6.2e-28 98.5 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 CRK31617.1 - 1e-12 48.1 1.5 2.6e-12 46.9 0.9 1.9 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CRK31617.1 - 0.00078 19.3 0.0 0.0029 17.5 0.0 1.9 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Amidohydro_1 PF01979.20 CRK31618.1 - 2.3e-21 76.5 1.2 8.4e-18 64.8 0.1 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 CRK31618.1 - 1.8e-12 47.5 1.5 7.5e-11 42.2 0.1 2.2 2 0 0 2 2 2 2 Amidohydrolase family Glyco_hydro_61 PF03443.14 CRK31619.1 - 7e-64 215.5 1.0 9.1e-64 215.2 1.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Arrestin_N PF00339.29 CRK31620.1 - 0.035 14.2 0.0 0.077 13.0 0.0 1.6 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain TPR_2 PF07719.17 CRK31621.1 - 0.00055 19.9 1.1 3.4 8.0 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 CRK31621.1 - 0.047 13.5 0.5 17 5.4 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 CRK31622.1 - 6.1e-05 23.2 7.1 0.001 19.3 4.2 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 CRK31622.1 - 0.0011 18.7 9.1 0.0027 17.5 0.3 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 CRK31622.1 - 0.0018 18.9 3.7 0.0046 17.6 3.7 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_4 PF07721.14 CRK31622.1 - 0.0029 18.1 5.1 0.73 10.6 0.3 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 CRK31622.1 - 0.0038 17.3 2.5 0.043 14.0 0.1 3.0 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 CRK31622.1 - 0.0061 16.5 5.6 0.015 15.3 0.2 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 CRK31622.1 - 0.0094 16.3 3.4 0.13 12.7 0.6 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 CRK31622.1 - 0.014 15.9 3.2 0.066 13.7 3.8 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 CRK31622.1 - 0.048 13.8 0.3 0.048 13.8 0.3 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CRK31622.1 - 0.05 13.8 1.4 0.11 12.8 1.4 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 CRK31622.1 - 0.063 14.1 7.9 0.14 13.0 0.2 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 CRK31622.1 - 0.16 11.8 0.3 0.16 11.8 0.3 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Ub-Mut7C PF14451.6 CRK31624.1 - 0.11 12.3 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Mut7-C ubiquitin TRP PF06011.12 CRK31626.1 - 1.9e-29 102.7 0.2 2e-29 102.6 0.2 1.0 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel HSP70 PF00012.20 CRK31628.1 - 5.3e-77 259.4 1.7 5.8e-77 259.3 1.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CRK31628.1 - 9.7e-07 27.9 0.1 1.3e-06 27.5 0.1 1.1 1 0 0 1 1 1 1 MreB/Mbl protein DDR PF08841.10 CRK31628.1 - 0.0042 16.1 0.1 0.16 10.9 0.1 2.1 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain TcdA_TcdB PF12919.7 CRK31628.1 - 0.017 14.4 0.2 0.027 13.8 0.2 1.4 1 1 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain HEPPP_synt_1 PF07307.11 CRK31628.1 - 0.022 14.4 1.2 0.033 13.8 1.2 1.2 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Hydantoinase_A PF01968.18 CRK31628.1 - 0.14 11.4 1.8 0.96 8.6 0.1 2.2 1 1 1 2 2 2 0 Hydantoinase/oxoprolinase Borrelia_orfA PF02414.15 CRK31628.1 - 0.78 9.3 8.7 3 7.4 6.7 2.4 1 1 0 2 2 2 0 Borrelia ORF-A DUF4023 PF13215.6 CRK31629.1 - 0.13 12.3 2.3 0.14 12.2 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4023) zinc_ribbon_9 PF14369.6 CRK31630.1 - 0.47 10.8 7.2 0.62 10.4 7.2 1.5 1 1 0 1 1 1 0 zinc-ribbon Pro_isomerase PF00160.21 CRK31631.1 - 2.2e-38 132.0 0.1 2.6e-38 131.8 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Thioredoxin_3 PF13192.6 CRK31631.1 - 0.067 13.2 0.0 0.086 12.9 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain TEA PF01285.18 CRK31632.1 - 4.6e-21 74.7 0.6 9.8e-21 73.6 0.6 1.6 1 0 0 1 1 1 1 TEA/ATTS domain Integrin_b_cyt PF08725.11 CRK31632.1 - 0.22 11.3 0.6 0.82 9.4 0.1 2.2 2 0 0 2 2 2 0 Integrin beta cytoplasmic domain RRM_1 PF00076.22 CRK31633.1 - 4.1e-61 202.7 1.0 1.2e-16 60.3 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CRK31633.1 - 8e-06 25.9 0.1 1.5 9.0 0.0 4.5 4 0 0 4 4 4 2 RNA recognition motif RRM_occluded PF16842.5 CRK31633.1 - 4.8e-05 23.1 0.0 1 9.3 0.0 4.4 5 0 0 5 5 5 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 CRK31633.1 - 7.4e-05 22.7 0.0 0.0091 16.0 0.0 3.0 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 CRK31633.1 - 0.00015 21.7 4.2 0.2 11.7 0.0 5.2 6 0 0 6 6 6 1 RNA binding motif SET_assoc PF11767.8 CRK31633.1 - 0.0025 17.4 0.0 14 5.4 0.0 3.5 3 0 0 3 3 3 1 Histone lysine methyltransferase SET associated Limkain-b1 PF11608.8 CRK31633.1 - 0.013 15.6 1.8 0.27 11.4 0.1 3.6 4 0 0 4 4 4 0 Limkain b1 RRM_Rrp7 PF17799.1 CRK31633.1 - 0.11 12.3 0.1 5.6 6.8 0.0 2.9 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain DUF1179 PF06678.11 CRK31633.1 - 1.6 8.8 7.8 0.93 9.5 4.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1179) Dynein_light PF01221.18 CRK31634.1 - 8.8e-40 134.9 0.8 1e-39 134.7 0.8 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Pkinase PF00069.25 CRK31636.1 - 1.4e-23 83.7 0.0 1.7e-23 83.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK31636.1 - 2.3e-09 36.9 0.0 2.7e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 CRK31637.1 - 4.6e-12 46.4 0.3 6.5e-12 45.9 0.3 1.2 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 CRK31637.1 - 2.3e-09 37.4 0.5 3.6e-09 36.8 0.5 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 CRK31637.1 - 2.4e-05 24.7 1.6 4.5e-05 23.8 1.6 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_17 PF18012.1 CRK31637.1 - 0.032 14.0 0.0 0.058 13.1 0.0 1.4 1 0 0 1 1 1 0 PH domain PH_6 PF15406.6 CRK31637.1 - 0.47 10.8 0.1 0.47 10.8 0.1 2.3 2 1 1 3 3 3 0 Pleckstrin homology domain Gly_kinase PF02595.15 CRK31638.1 - 3.7e-58 197.3 6.4 4e-58 197.2 6.4 1.0 1 0 0 1 1 1 1 Glycerate kinase family RRM_1 PF00076.22 CRK31639.1 - 0.00014 21.6 0.0 0.00036 20.3 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CRK31639.1 - 0.0022 17.8 0.0 0.0044 16.9 0.0 1.5 1 0 0 1 1 1 1 Occluded RNA-recognition motif DNA_pol_B_exo1 PF03104.19 CRK31640.1 - 8.3e-19 67.9 0.0 9.2e-19 67.8 0.0 1.0 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain Sterol_MT_C PF08498.10 CRK31642.1 - 4.6e-29 100.5 0.2 8.1e-29 99.7 0.2 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 CRK31642.1 - 6.7e-09 36.3 0.0 1.4e-08 35.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK31642.1 - 8.5e-06 26.4 0.0 1.7e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK31642.1 - 0.00096 19.0 0.0 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CRK31642.1 - 0.0013 18.6 0.0 0.0018 18.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK31642.1 - 0.003 18.3 0.0 0.0068 17.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CRK31642.1 - 0.014 14.7 0.1 0.096 12.0 0.0 2.2 3 0 0 3 3 3 0 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.16 CRK31642.1 - 0.21 10.1 0.0 0.24 9.9 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase PALP PF00291.25 CRK31645.1 - 1.1e-53 182.6 5.6 5e-52 177.1 5.6 2.0 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Aminotran_1_2 PF00155.21 CRK31646.1 - 1.4e-17 63.9 0.0 1.9e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 CRK31646.1 - 0.0017 17.2 0.0 0.098 11.4 0.0 2.6 3 0 0 3 3 3 2 Alanine-glyoxylate amino-transferase MFS_1 PF07690.16 CRK31647.1 - 8.4e-38 130.2 46.4 8.4e-38 130.2 46.4 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK31647.1 - 1.7e-09 37.1 10.4 1.7e-09 37.1 10.4 2.1 3 0 0 3 3 3 1 Sugar (and other) transporter Sugar_tr PF00083.24 CRK31648.1 - 5.6e-35 121.1 0.4 7.4e-35 120.7 0.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK31648.1 - 1.7e-05 24.0 5.7 3.1e-05 23.1 5.8 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Cellulase PF00150.18 CRK31649.1 - 0.00019 21.0 0.0 0.00041 19.9 0.0 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) MethyTransf_Reg PF10119.9 CRK31649.1 - 0.065 13.9 0.1 0.14 12.9 0.1 1.5 1 0 0 1 1 1 0 Predicted methyltransferase regulatory domain Fungal_trans_2 PF11951.8 CRK31650.1 - 3.5e-14 52.4 1.0 4.6e-14 52.0 1.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pyr_redox_2 PF07992.14 CRK31650.1 - 1.2e-07 31.3 0.0 0.028 13.6 0.0 3.2 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CRK31650.1 - 0.0015 18.5 0.0 0.089 12.8 0.0 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 CRK31650.1 - 0.011 15.3 0.1 0.053 13.1 0.1 2.1 1 1 1 2 2 2 0 FAD dependent oxidoreductase CCDC71L PF15374.6 CRK31650.1 - 0.11 11.8 0.2 0.23 10.7 0.0 1.6 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 71L MCRA PF06100.11 CRK31650.1 - 0.16 10.7 0.0 0.24 10.1 0.0 1.2 1 0 0 1 1 1 0 MCRA family MCM_OB PF17207.3 CRK31651.1 - 1.3e-28 99.3 1.2 1.6e-28 99.0 1.2 1.1 1 0 0 1 1 1 1 MCM OB domain WD40 PF00400.32 CRK31653.1 - 1.1e-22 79.9 4.6 1.7e-10 41.3 0.0 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK31653.1 - 7e-10 39.1 0.0 0.0024 18.1 0.0 3.1 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 CRK31653.1 - 0.00043 18.7 0.0 0.00054 18.4 0.0 1.1 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz PALB2_WD40 PF16756.5 CRK31653.1 - 0.00089 18.3 0.3 0.0055 15.7 0.1 1.9 1 1 1 2 2 2 1 Partner and localizer of BRCA2 WD40 domain Ge1_WD40 PF16529.5 CRK31653.1 - 0.0047 15.9 0.1 0.058 12.3 0.0 2.3 1 1 2 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein HPS3_N PF14761.6 CRK31653.1 - 0.0069 15.9 0.0 0.052 13.1 0.0 1.9 1 1 0 2 2 2 1 Hermansky-Pudlak syndrome 3 DUF1513 PF07433.11 CRK31653.1 - 0.0087 15.2 0.1 0.58 9.2 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1513) Hira PF07569.11 CRK31653.1 - 0.11 12.2 0.2 4.2 7.0 0.2 2.2 1 1 0 1 1 1 0 TUP1-like enhancer of split zf-C2H2 PF00096.26 CRK31654.1 - 4.5e-15 55.2 20.7 0.00013 22.2 0.1 5.6 6 0 0 6 6 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CRK31654.1 - 7e-10 38.9 20.5 0.068 14.0 0.2 6.0 6 0 0 6 6 6 4 C2H2-type zinc finger FOXP-CC PF16159.5 CRK31654.1 - 3.7e-06 27.5 15.0 0.00013 22.5 0.4 4.4 4 1 0 4 4 4 1 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 CRK31654.1 - 0.001 19.3 0.3 0.37 10.9 0.3 2.4 1 1 1 2 2 2 2 Aberrant zinc-finger zf-met PF12874.7 CRK31654.1 - 0.0018 18.6 14.2 0.12 12.8 0.1 5.5 6 0 0 6 6 6 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CRK31654.1 - 0.0052 17.0 15.8 1.6 9.1 0.9 5.2 6 0 0 6 6 6 2 Zinc-finger double-stranded RNA-binding DUF4187 PF13821.6 CRK31654.1 - 0.0061 16.3 1.5 0.022 14.5 0.2 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4187) zf_Hakai PF18408.1 CRK31654.1 - 0.043 13.5 13.1 0.11 12.2 0.0 5.0 4 1 1 5 5 5 0 C2H2 Hakai zinc finger domain zf-C2H2_8 PF15909.5 CRK31654.1 - 0.048 14.0 0.6 14 6.1 0.0 2.8 2 1 1 3 3 3 0 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 CRK31654.1 - 0.17 12.0 0.2 0.17 12.0 0.2 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 CRK31654.1 - 0.48 11.1 6.2 1.1 9.9 0.9 3.1 2 1 2 4 4 4 0 Zinc finger C2H2-type, 3 repeats zf-H2C2_5 PF13909.6 CRK31654.1 - 2.6 7.9 26.2 1 9.2 0.1 5.1 6 0 0 6 6 6 0 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 CRK31654.1 - 4.5 7.1 10.7 45 3.9 0.1 5.0 6 0 0 6 6 6 0 zinc-finger C2H2-type XPG_I PF00867.18 CRK31656.1 - 1.7e-25 89.2 0.0 6.1e-25 87.4 0.0 1.8 2 0 0 2 2 2 1 XPG I-region XPG_I_2 PF12813.7 CRK31656.1 - 0.0014 18.2 0.3 0.0044 16.5 0.0 1.8 1 1 1 2 2 2 1 XPG domain containing DUF1943 PF09172.11 CRK31656.1 - 0.02 14.2 0.1 0.025 13.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) DUF2229 PF09989.9 CRK31656.1 - 0.16 11.6 0.1 0.26 10.9 0.1 1.3 2 0 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) CLASP_N PF12348.8 CRK31657.1 - 0.00029 20.5 0.0 0.00034 20.2 0.0 1.1 1 0 0 1 1 1 1 CLASP N terminal HEAT PF02985.22 CRK31657.1 - 0.026 14.8 1.9 3.4 8.2 0.1 3.7 5 0 0 5 5 5 0 HEAT repeat MOR2-PAG1_C PF14225.6 CRK31657.1 - 0.13 12.1 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 Cell morphogenesis C-terminal zf-C3HC4_3 PF13920.6 CRK31658.1 - 3e-06 27.0 7.6 5.8e-06 26.1 7.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CRK31658.1 - 4.4e-06 26.5 10.4 8e-06 25.6 10.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CRK31658.1 - 1.3e-05 25.4 9.9 1.3e-05 25.4 9.9 1.9 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 CRK31658.1 - 0.0005 20.0 8.6 0.0005 20.0 8.6 1.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CRK31658.1 - 0.00083 19.2 11.7 0.00083 19.2 11.7 2.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CRK31658.1 - 0.00087 19.3 7.5 0.0017 18.3 7.5 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 CRK31658.1 - 0.0047 16.8 9.6 0.92 9.4 10.1 2.5 1 1 1 2 2 2 2 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 CRK31658.1 - 0.0056 16.7 1.7 0.0087 16.1 1.7 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 CRK31658.1 - 0.02 15.1 8.2 0.042 14.0 8.2 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Zn-ribbon_8 PF09723.10 CRK31658.1 - 0.043 13.9 3.6 2.2 8.5 0.8 2.5 2 0 0 2 2 2 0 Zinc ribbon domain PhnA_Zn_Ribbon PF08274.12 CRK31658.1 - 0.11 12.5 0.0 0.11 12.5 0.0 2.7 3 0 0 3 3 3 0 PhnA Zinc-Ribbon zf-RING_4 PF14570.6 CRK31658.1 - 0.14 11.9 9.5 0.23 11.3 2.8 2.6 3 0 0 3 3 2 0 RING/Ubox like zinc-binding domain FlhC PF05280.11 CRK31658.1 - 0.61 9.8 2.5 10 5.8 1.5 2.2 1 1 1 2 2 2 0 Flagellar transcriptional activator (FlhC) zf-C4_Topoisom PF01396.19 CRK31658.1 - 0.77 9.6 4.6 10 6.0 0.1 2.4 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger KH_1 PF00013.29 CRK31660.1 - 1.3e-11 44.2 0.1 1.3e-08 34.6 0.0 2.7 2 1 0 2 2 2 2 KH domain DUF3947 PF13135.6 CRK31660.1 - 0.059 13.6 0.3 0.38 11.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3947) Peptidase_M24 PF00557.24 CRK31662.1 - 2.5e-39 135.2 0.0 3.7e-39 134.6 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Glyco_hydro_28 PF00295.17 CRK31663.1 - 4.5e-39 134.4 1.6 6e-39 134.0 1.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Transketolase_N PF00456.21 CRK31664.1 - 6.4e-131 436.3 0.0 9.3e-131 435.7 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 CRK31664.1 - 1.4e-40 138.9 0.0 6e-30 104.2 0.1 2.6 1 1 1 2 2 2 2 Transketolase, pyrimidine binding domain DXP_synthase_N PF13292.6 CRK31664.1 - 3e-08 33.2 0.0 9e-08 31.6 0.0 1.7 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_C PF02780.20 CRK31664.1 - 2.4e-07 30.7 0.0 6.1e-07 29.4 0.0 1.8 1 0 0 1 1 1 1 Transketolase, C-terminal domain E1_dh PF00676.20 CRK31664.1 - 2.7e-07 29.8 0.1 4.7e-07 29.0 0.1 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component Fungal_trans_2 PF11951.8 CRK31665.1 - 3.8e-16 58.9 3.1 5.5e-13 48.5 1.9 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK31665.1 - 1.1e-06 28.7 12.2 2.1e-06 27.7 12.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 CRK31666.1 - 5.3e-09 35.8 0.0 5.6e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK31666.1 - 0.00012 21.4 0.0 0.00015 21.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CRK31666.1 - 0.00095 18.6 0.0 0.0011 18.4 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CRK31666.1 - 0.2 11.6 0.0 0.22 11.4 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family Sugar_tr PF00083.24 CRK31667.1 - 2.8e-105 352.8 13.2 3.3e-105 352.6 13.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK31667.1 - 3.2e-26 92.1 47.9 1.5e-23 83.3 22.6 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 CRK31667.1 - 0.0026 16.1 0.8 0.0057 15.0 0.8 1.6 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family YbhQ PF11076.8 CRK31667.1 - 0.049 13.6 0.3 0.13 12.2 0.3 1.7 1 0 0 1 1 1 0 Putative inner membrane protein YbhQ ECH_1 PF00378.20 CRK31668.1 - 1.5e-51 175.1 0.0 2.9e-51 174.2 0.0 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CRK31668.1 - 3.4e-21 76.1 0.2 9.2e-18 64.8 0.6 2.7 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase HAUS6_N PF14661.6 CRK31669.1 - 7.4e-57 192.6 0.6 1.3e-56 191.8 0.6 1.4 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus Ribosomal_S21 PF01165.20 CRK31670.1 - 4e-10 39.2 3.8 6e-10 38.7 3.8 1.3 1 0 0 1 1 1 1 Ribosomal protein S21 FAT PF02259.23 CRK31671.1 - 9.3e-32 110.6 0.0 1.1e-31 110.4 0.0 1.0 1 0 0 1 1 1 1 FAT domain TPR_8 PF13181.6 CRK31671.1 - 0.00039 20.4 0.2 0.0011 19.0 0.2 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 CRK31671.1 - 0.094 12.9 1.2 0.16 12.1 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Glyco_hydro_3 PF00933.21 CRK31672.1 - 1.8e-45 155.7 0.0 2.1e-45 155.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain PALP PF00291.25 CRK31673.1 - 6.4e-45 153.8 0.2 7.7e-45 153.5 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Arylsulfotran_2 PF14269.6 CRK31674.1 - 1e-42 146.6 0.0 1.1e-42 146.4 0.0 1.0 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 CRK31674.1 - 7.6e-18 64.6 0.0 3.7e-17 62.3 0.0 1.8 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) PQQ_2 PF13360.6 CRK31674.1 - 0.0074 15.9 0.3 0.018 14.6 0.3 1.9 1 1 0 1 1 1 1 PQQ-like domain PQQ PF01011.21 CRK31674.1 - 0.025 14.5 0.0 0.65 10.0 0.0 3.0 3 0 0 3 3 3 0 PQQ enzyme repeat HEAT_2 PF13646.6 CRK31676.1 - 0.00022 21.5 5.2 0.0091 16.4 0.4 2.0 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.22 CRK31676.1 - 0.00069 19.7 0.1 4.1 7.9 0.0 3.4 3 0 0 3 3 3 1 HEAT repeat Cnd1 PF12717.7 CRK31676.1 - 0.11 12.5 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 Glycos_transf_2 PF00535.26 CRK31677.1 - 2.3e-20 73.1 0.0 2.9e-20 72.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 CRK31677.1 - 1.2e-07 31.9 0.1 1.4e-07 31.7 0.1 1.3 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 CRK31677.1 - 8.9e-05 22.1 0.0 0.00012 21.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 CRK31677.1 - 0.033 14.7 0.0 0.057 13.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 AAA_6 PF12774.7 CRK31679.1 - 0.049 12.6 0.0 0.07 12.1 0.0 1.1 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region THOC2_N PF16134.5 CRK31680.1 - 1.5e-60 205.6 0.0 1.6e-60 205.5 0.0 1.0 1 0 0 1 1 1 1 THO complex subunit 2 N-terminus BCS1_N PF08740.11 CRK31683.1 - 5.7e-41 140.6 0.0 8.1e-41 140.1 0.0 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 CRK31683.1 - 1.1e-08 35.6 0.0 1.6e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) GTSE1_N PF15259.6 CRK31683.1 - 0.075 13.2 0.1 0.13 12.5 0.1 1.3 1 0 0 1 1 1 0 G-2 and S-phase expressed 1 Hydrophobin_2 PF06766.11 CRK31684.1 - 1.5e-24 85.7 12.1 2e-24 85.3 12.1 1.2 1 0 0 1 1 1 1 Fungal hydrophobin Fungal_trans PF04082.18 CRK31685.1 - 1.8e-20 73.1 0.1 4.6e-20 71.8 0.1 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK31685.1 - 6.6e-05 22.9 9.1 0.00012 22.2 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SUIM_assoc PF16619.5 CRK31685.1 - 0.017 15.1 2.2 0.041 14.0 2.2 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF1206 PF06724.11 CRK31685.1 - 0.06 13.4 1.1 0.14 12.3 0.1 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) MFS_1 PF07690.16 CRK31686.1 - 5.5e-35 120.9 25.9 5.5e-35 120.9 25.9 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1003 PF06210.11 CRK31686.1 - 3 8.0 5.0 15 5.7 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1003) DUF4131 PF13567.6 CRK31686.1 - 6.2 6.4 7.8 29 4.2 0.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) p450 PF00067.22 CRK31687.1 - 3e-32 112.0 0.0 3.7e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 CRISPR_Cse2 PF09485.10 CRK31688.1 - 0.017 15.6 2.0 0.02 15.4 2.0 1.0 1 0 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) DUF4386 PF14329.6 CRK31688.1 - 0.073 12.9 0.0 0.096 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4386) Ring_hydroxyl_B PF00866.18 CRK31689.1 - 0.028 14.5 0.0 0.065 13.3 0.0 1.6 1 0 0 1 1 1 0 Ring hydroxylating beta subunit zf-MYND PF01753.18 CRK31690.1 - 0.0041 17.2 9.6 0.011 15.8 9.6 1.8 1 0 0 1 1 1 1 MYND finger Ish1 PF10281.9 CRK31691.1 - 1.1e-93 307.2 23.7 2.7e-15 56.4 0.0 8.5 8 0 0 8 8 8 8 Putative stress-responsive nuclear envelope protein SAP PF02037.27 CRK31691.1 - 4.9e-11 42.1 0.0 0.77 9.6 0.0 8.2 10 0 0 10 10 10 2 SAP domain HeH PF12949.7 CRK31691.1 - 9.4e-07 28.4 0.1 1.7 8.4 0.0 6.4 6 1 1 7 7 7 1 HeH/LEM domain Slx4 PF09494.10 CRK31691.1 - 3.8e-06 26.7 2.3 17 5.4 0.0 6.9 8 0 0 8 8 8 2 Slx4 endonuclease CPSase_sm_chain PF00988.22 CRK31691.1 - 0.0004 20.2 0.0 2.4 8.0 0.0 4.3 5 1 1 6 6 6 2 Carbamoyl-phosphate synthase small chain, CPSase domain SAM_2 PF07647.17 CRK31691.1 - 0.035 14.2 0.6 2.4 8.3 0.1 3.6 4 0 0 4 4 4 0 SAM domain (Sterile alpha motif) RAMA PF18755.1 CRK31691.1 - 7.5 7.0 10.2 2.3 8.7 0.3 3.5 1 1 2 3 3 3 0 Restriction Enzyme Adenine Methylase Associated Hydrophobin_2 PF06766.11 CRK31692.1 - 3.4e-27 94.2 10.0 4.2e-27 93.9 10.0 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Prot_ATP_ID_OB PF16450.5 CRK31693.1 - 1.1e-18 66.9 0.1 2.1e-18 66.0 0.1 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA PF00004.29 CRK31693.1 - 6.6e-09 36.3 0.1 1.3e-08 35.3 0.1 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CRK31693.1 - 1.9e-06 27.6 0.0 4.3e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 CRK31693.1 - 0.0012 18.6 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CRK31693.1 - 0.002 18.5 0.4 0.006 17.0 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.21 CRK31693.1 - 0.0074 15.7 0.1 0.017 14.6 0.0 1.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 CRK31693.1 - 0.013 15.8 1.2 0.037 14.3 0.0 2.2 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 CRK31693.1 - 0.013 15.6 0.0 0.034 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 CRK31693.1 - 0.014 15.4 0.8 0.022 14.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PhoH PF02562.16 CRK31693.1 - 0.026 14.0 0.1 0.054 12.9 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 CRK31693.1 - 0.058 13.1 0.1 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 CRK31693.1 - 0.17 11.4 0.0 0.35 10.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_11 PF13086.6 CRK31693.1 - 0.19 11.5 6.4 0.46 10.2 0.0 2.7 3 0 0 3 3 3 0 AAA domain RPN2_C PF18004.1 CRK31693.1 - 8.4 6.3 9.8 1.2 9.0 5.8 1.6 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain tRNA_lig_CPD PF08302.11 CRK31695.1 - 7.6e-89 297.5 0.0 1.1e-88 297.0 0.0 1.2 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain RNA_lig_T4_1 PF09511.10 CRK31695.1 - 1e-84 283.8 0.0 3e-84 282.3 0.0 1.8 2 0 0 2 2 2 1 RNA ligase tRNA_lig_kinase PF08303.11 CRK31695.1 - 2.3e-53 180.7 0.1 6.7e-53 179.2 0.0 1.8 2 0 0 2 2 2 1 tRNA ligase kinase domain Ribosomal_L10 PF00466.20 CRK31695.1 - 0.00077 19.6 0.0 0.0027 17.8 0.0 2.0 1 1 0 1 1 1 1 Ribosomal protein L10 Ribonuc_P_40 PF08584.11 CRK31696.1 - 3.6e-56 190.6 0.0 5.3e-55 186.7 0.0 2.0 2 0 0 2 2 2 1 Ribonuclease P 40kDa (Rpp40) subunit 5-nucleotidase PF06189.12 CRK31696.1 - 0.075 12.0 0.0 0.1 11.5 0.0 1.1 1 0 0 1 1 1 0 5'-nucleotidase UPF0020 PF01170.18 CRK31697.1 - 2.4e-09 37.2 0.0 1.7e-07 31.1 0.0 2.2 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Vac_ImportDeg PF09783.9 CRK31699.1 - 2.1e-68 229.2 1.5 2.7e-68 228.9 1.5 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein Podoplanin PF05808.11 CRK31699.1 - 0.09 12.9 4.5 0.16 12.0 4.5 1.4 1 0 0 1 1 1 0 Podoplanin Mago_nashi PF02792.14 CRK31702.1 - 8.7e-73 243.1 0.2 9.8e-73 242.9 0.2 1.0 1 0 0 1 1 1 1 Mago nashi protein Coatamer_beta_C PF07718.12 CRK31704.1 - 3.9e-59 198.6 0.2 9e-59 197.4 0.2 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.6 CRK31704.1 - 1e-57 193.7 0.1 3.5e-57 191.9 0.0 1.9 2 0 0 2 2 2 1 Coatomer beta subunit appendage platform Coatomer_g_Cpla PF16381.5 CRK31704.1 - 0.00017 21.7 0.0 0.00045 20.3 0.0 1.8 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform AP4E_app_platf PF14807.6 CRK31704.1 - 0.0048 17.2 0.2 0.013 15.8 0.2 1.8 1 0 0 1 1 1 1 Adaptin AP4 complex epsilon appendage platform B2-adapt-app_C PF09066.10 CRK31704.1 - 0.074 13.1 0.1 0.17 12.0 0.1 1.6 1 0 0 1 1 1 0 Beta2-adaptin appendage, C-terminal sub-domain Glyco_hydro_7 PF00840.20 CRK31706.1 - 4.3e-176 585.9 20.5 5.1e-93 312.2 2.2 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 7 UBD PF16455.5 CRK31706.1 - 5.5e-37 126.2 0.0 1.2e-36 125.1 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-binding domain Pre-SET PF05033.16 CRK31706.1 - 6.9e-17 62.1 1.7 6.9e-17 62.1 1.7 4.1 4 1 0 4 4 4 1 Pre-SET motif SET PF00856.28 CRK31706.1 - 1.9e-16 60.9 0.0 8.3e-16 58.8 0.0 2.2 1 1 0 1 1 1 1 SET domain ubiquitin PF00240.23 CRK31706.1 - 3.7e-05 23.4 0.0 7.1e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CRK31706.1 - 0.076 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like CALCOCO1 PF07888.11 CRK31708.1 - 1.7e-06 27.2 18.6 1.7e-06 27.2 18.6 3.9 2 1 1 3 3 2 1 Calcium binding and coiled-coil domain (CALCOCO1) like CENP-F_leu_zip PF10473.9 CRK31708.1 - 0.00034 20.7 64.7 0.036 14.1 2.2 6.4 2 2 5 7 7 7 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_TATA_bd PF12325.8 CRK31708.1 - 0.00098 19.3 55.8 0.022 14.9 1.0 6.7 2 1 4 7 7 7 4 TATA element modulatory factor 1 TATA binding Laminin_II PF06009.12 CRK31708.1 - 0.075 13.0 0.1 0.075 13.0 0.1 6.0 4 2 3 7 7 7 0 Laminin Domain II ZapB PF06005.12 CRK31708.1 - 0.14 12.7 63.2 0.3 11.6 6.6 8.6 3 3 3 7 7 7 0 Cell division protein ZapB ATG16 PF08614.11 CRK31708.1 - 0.35 11.1 87.3 1 9.6 0.4 7.1 2 2 3 5 5 5 0 Autophagy protein 16 (ATG16) MAD PF05557.13 CRK31708.1 - 0.75 8.1 52.8 0.66 8.3 0.9 3.5 2 1 1 3 3 3 0 Mitotic checkpoint protein KASH_CCD PF14662.6 CRK31708.1 - 0.84 9.4 60.2 0.027 14.3 8.5 6.1 2 2 5 7 7 6 0 Coiled-coil region of CCDC155 or KASH Vac_Fusion PF02346.16 CRK31708.1 - 1.3 8.7 7.5 1 9.0 1.5 3.5 3 1 0 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 TACC_C PF05010.14 CRK31708.1 - 1.7 8.4 42.7 0.61 9.8 8.0 4.1 2 1 2 4 4 4 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal bZIP_1 PF00170.21 CRK31708.1 - 2 8.6 51.2 0.19 11.8 0.3 10.1 5 3 5 11 11 11 0 bZIP transcription factor TSC22 PF01166.18 CRK31708.1 - 3 8.2 25.3 16 5.9 0.1 8.2 6 4 2 8 8 8 0 TSC-22/dip/bun family DUF1664 PF07889.12 CRK31708.1 - 3.5 7.7 30.2 0.073 13.1 3.1 5.5 2 2 1 5 5 5 0 Protein of unknown function (DUF1664) Filament PF00038.21 CRK31708.1 - 3.6 7.1 49.7 1.9 8.0 16.8 4.4 2 1 3 5 5 5 0 Intermediate filament protein YabA PF06156.13 CRK31708.1 - 7.7 7.2 38.1 60 4.3 0.7 7.0 2 2 4 6 6 6 0 Initiation control protein YabA HOOK PF05622.12 CRK31708.1 - 7.8 4.5 61.0 0.033 12.3 37.1 3.7 2 1 1 3 3 3 0 HOOK protein Nop52 PF05997.12 CRK31710.1 - 4e-52 177.1 0.1 6.2e-52 176.5 0.1 1.3 1 0 0 1 1 1 1 Nucleolar protein,Nop52 DUF3685 PF12452.8 CRK31710.1 - 0.0078 15.9 0.1 0.014 15.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3685) Glycos_transf_3 PF00591.21 CRK31712.1 - 2.9e-63 213.8 0.0 6.4e-63 212.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain DAGK_cat PF00781.24 CRK31712.1 - 9.5e-16 57.6 0.0 2.4e-15 56.3 0.0 1.7 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Glycos_trans_3N PF02885.17 CRK31712.1 - 2e-09 37.1 0.1 6.7e-09 35.5 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain NARP1 PF12569.8 CRK31714.1 - 5e-178 593.2 29.4 8.6e-178 592.4 21.6 2.3 1 1 1 2 2 2 2 NMDA receptor-regulated protein 1 Cid2 PF09774.9 CRK31714.1 - 2e-21 77.1 2.6 7.6e-21 75.2 0.0 2.6 2 0 0 2 2 2 1 Caffeine-induced death protein 2 TPR_16 PF13432.6 CRK31714.1 - 4.9e-16 59.1 40.2 0.00014 22.4 0.4 10.6 9 2 1 10 10 9 4 Tetratricopeptide repeat TPR_2 PF07719.17 CRK31714.1 - 6.1e-14 50.9 32.2 1.6e-05 24.7 0.1 10.3 11 1 0 11 11 10 4 Tetratricopeptide repeat TPR_19 PF14559.6 CRK31714.1 - 1.4e-12 48.0 35.7 8.3e-05 23.0 0.8 7.2 7 1 0 7 7 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 CRK31714.1 - 6.1e-12 45.0 16.7 2.5e-08 33.4 0.5 5.9 7 0 0 7 7 7 3 TPR repeat TPR_14 PF13428.6 CRK31714.1 - 4.4e-11 42.6 38.1 0.0005 20.7 0.4 10.4 9 5 4 13 13 10 4 Tetratricopeptide repeat TPR_1 PF00515.28 CRK31714.1 - 6.5e-09 35.2 21.3 2.8e-05 23.7 0.0 8.4 8 1 0 8 8 8 3 Tetratricopeptide repeat ANAPC3 PF12895.7 CRK31714.1 - 1e-08 35.2 16.1 0.0008 19.6 0.2 5.1 4 2 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 CRK31714.1 - 3.4e-08 33.3 8.2 0.68 10.4 0.0 8.6 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_9 PF13371.6 CRK31714.1 - 2.2e-05 24.5 20.8 0.0015 18.6 0.5 6.1 5 2 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 CRK31714.1 - 6.1e-05 22.8 11.2 0.0041 17.1 0.1 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 CRK31714.1 - 0.0024 17.9 24.8 0.015 15.5 0.0 9.0 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_10 PF13374.6 CRK31714.1 - 0.021 14.7 10.1 3.1 7.8 0.1 6.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 CRK31714.1 - 0.11 12.7 28.7 0.37 11.1 0.1 7.5 9 0 0 9 9 7 0 Tetratricopeptide repeat TPR_6 PF13174.6 CRK31714.1 - 0.14 12.9 27.8 0.43 11.3 0.2 8.1 9 0 0 9 9 7 0 Tetratricopeptide repeat DUF4718 PF15842.5 CRK31714.1 - 0.23 11.2 1.0 0.47 10.2 1.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) Fis1_TPR_C PF14853.6 CRK31714.1 - 1.3 9.1 14.0 11 6.2 0.1 5.8 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.17 CRK31714.1 - 9.8 6.6 13.4 0.2 12.1 1.1 3.9 4 1 1 5 5 4 0 Bacterial transcriptional activator domain Nop52 PF05997.12 CRK31716.1 - 2.9e-74 249.5 0.2 2.2e-46 158.4 0.0 2.4 2 0 0 2 2 2 2 Nucleolar protein,Nop52 Glyco_hydro_43 PF04616.14 CRK31716.1 - 3.4e-68 230.1 1.9 5.4e-68 229.4 1.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glycos_transf_3 PF00591.21 CRK31716.1 - 1e-62 212.0 0.0 2.2e-62 211.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain DAGK_cat PF00781.24 CRK31716.1 - 2.6e-20 72.3 0.1 2.6e-20 72.3 0.1 2.0 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain Glycos_trans_3N PF02885.17 CRK31716.1 - 2.5e-09 36.9 0.0 9.2e-09 35.0 0.0 2.0 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain CALCOCO1 PF07888.11 CRK31716.1 - 3.6e-06 26.1 19.8 3.6e-06 26.1 19.8 3.6 2 1 1 3 3 3 1 Calcium binding and coiled-coil domain (CALCOCO1) like GH43_C2 PF17851.1 CRK31716.1 - 0.002 17.9 0.0 0.0098 15.6 0.0 2.2 2 0 0 2 2 2 1 Beta xylosidase C-terminal Concanavalin A-like domain TMF_TATA_bd PF12325.8 CRK31716.1 - 0.023 14.9 51.8 0.082 13.1 1.3 6.4 3 1 3 6 6 6 0 TATA element modulatory factor 1 TATA binding CENP-F_leu_zip PF10473.9 CRK31716.1 - 0.055 13.5 64.6 0.085 12.9 3.2 6.2 2 2 4 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Laminin_II PF06009.12 CRK31716.1 - 0.085 12.9 0.1 0.085 12.9 0.1 5.4 4 2 2 6 6 6 0 Laminin Domain II KASH_CCD PF14662.6 CRK31716.1 - 1.4 8.7 52.5 0.0097 15.8 9.8 5.4 2 2 3 6 6 4 0 Coiled-coil region of CCDC155 or KASH DUF1664 PF07889.12 CRK31716.1 - 3.5 7.7 24.2 0.058 13.4 3.8 5.0 4 2 0 4 4 4 0 Protein of unknown function (DUF1664) MAD PF05557.13 CRK31716.1 - 7.4 4.8 50.9 1.1 7.5 17.3 3.3 2 1 1 3 3 3 0 Mitotic checkpoint protein Vac_Fusion PF02346.16 CRK31716.1 - 8.6 6.1 7.4 1.9 8.2 1.9 2.7 3 0 0 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 ATG16 PF08614.11 CRK31716.1 - 9.3 6.4 78.1 0.69 10.1 13.9 6.2 2 2 4 6 6 6 0 Autophagy protein 16 (ATG16) NARP1 PF12569.8 CRK31718.1 - 6.1e-178 592.9 21.1 6.1e-178 592.9 21.1 1.8 1 1 1 2 2 2 1 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 CRK31718.1 - 3.2e-14 51.8 32.1 1.2e-05 25.0 0.1 10.3 11 1 0 11 11 11 5 Tetratricopeptide repeat TPR_11 PF13414.6 CRK31718.1 - 1.5e-12 47.0 15.2 2e-08 33.8 0.5 5.5 6 0 0 6 6 6 3 TPR repeat TPR_19 PF14559.6 CRK31718.1 - 7.2e-12 45.6 33.2 6.6e-05 23.3 0.8 6.5 6 2 1 7 7 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 CRK31718.1 - 1.9e-09 37.5 41.6 0.00043 20.9 0.4 9.6 8 4 4 12 12 8 4 Tetratricopeptide repeat TPR_16 PF13432.6 CRK31718.1 - 3.3e-09 37.2 48.2 0.00011 22.7 0.4 9.7 8 3 1 10 10 8 3 Tetratricopeptide repeat TPR_1 PF00515.28 CRK31718.1 - 9.1e-08 31.6 22.8 2.3e-05 24.0 0.0 7.7 8 1 0 8 8 7 3 Tetratricopeptide repeat TPR_9 PF13371.6 CRK31718.1 - 2.9e-05 24.1 21.4 0.0011 19.1 0.4 6.1 5 3 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 CRK31718.1 - 0.00011 22.0 12.0 0.0032 17.4 0.1 6.2 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 CRK31718.1 - 0.00033 20.8 14.7 0.54 10.7 0.0 7.7 9 0 0 9 9 8 2 Tetratricopeptide repeat FAT PF02259.23 CRK31718.1 - 0.00065 19.0 6.9 0.0013 18.1 0.5 3.4 2 2 2 4 4 4 1 FAT domain ANAPC3 PF12895.7 CRK31718.1 - 0.00094 19.4 15.6 0.14 12.4 0.1 5.2 4 2 2 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 CRK31718.1 - 0.012 15.8 0.0 0.012 15.8 0.0 8.4 10 0 0 10 10 9 0 Tetratricopeptide repeat TPR_6 PF13174.6 CRK31718.1 - 0.03 15.0 24.4 0.35 11.6 0.2 7.3 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_10 PF13374.6 CRK31718.1 - 0.095 12.6 8.8 2.5 8.1 0.1 5.5 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF4718 PF15842.5 CRK31718.1 - 0.16 11.7 1.0 0.38 10.6 1.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) TPR_12 PF13424.6 CRK31718.1 - 0.3 11.4 0.1 0.3 11.4 0.1 6.7 8 0 0 8 8 7 0 Tetratricopeptide repeat SET PF00856.28 CRK31718.1 - 7.6 6.9 7.5 3.4e+02 1.5 7.5 2.7 1 1 0 1 1 1 0 SET domain BTAD PF03704.17 CRK31718.1 - 8 6.9 13.9 0.24 11.8 1.5 4.1 4 1 0 4 4 4 0 Bacterial transcriptional activator domain Cid2 PF09774.9 CRK31720.1 - 7.2e-55 185.8 0.0 9.5e-55 185.4 0.0 1.1 1 0 0 1 1 1 1 Caffeine-induced death protein 2 Glyco_hydro_43 PF04616.14 CRK31721.1 - 2e-73 247.2 1.7 2.6e-73 246.9 1.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 CRK31721.1 - 2e-06 27.7 0.1 0.0031 17.3 0.0 2.3 1 1 1 2 2 2 2 Beta xylosidase C-terminal Concanavalin A-like domain Glyco_hydro_32N PF00251.20 CRK31721.1 - 0.021 14.4 0.2 0.14 11.7 0.0 1.8 1 1 1 2 2 2 0 Glycosyl hydrolases family 32 N-terminal domain Zn_clus PF00172.18 CRK31722.1 - 1.4e-05 25.1 19.7 0.014 15.5 5.9 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Prot_inhib_II PF02428.15 CRK31722.1 - 0.29 11.6 9.3 4.5 7.8 1.4 2.4 2 0 0 2 2 2 0 Potato type II proteinase inhibitor family 2-Hacid_dh_C PF02826.19 CRK31723.1 - 2.6e-57 193.0 0.0 3.9e-57 192.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CRK31723.1 - 3.7e-10 39.6 0.0 4.6e-09 36.0 0.0 2.1 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 CRK31723.1 - 1e-05 25.8 0.0 2e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 CRK31723.1 - 0.0055 16.8 0.0 0.01 15.9 0.0 1.4 1 1 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.12 CRK31723.1 - 0.0056 16.3 0.0 0.0093 15.5 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain AdoHcyase PF05221.17 CRK31724.1 - 1.5e-125 418.3 0.0 5.1e-72 242.5 0.3 2.6 2 1 1 3 3 3 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 CRK31724.1 - 2.1e-82 275.0 2.9 3.8e-82 274.1 2.9 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Mito_carr PF00153.27 CRK31724.1 - 3.9e-41 138.9 5.9 1.8e-16 59.8 0.3 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein JAB PF01398.21 CRK31724.1 - 3e-08 33.6 1.3 3.5e-07 30.2 1.3 2.3 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease 2-Hacid_dh_C PF02826.19 CRK31724.1 - 6.3e-06 25.7 0.2 1.9e-05 24.1 0.2 1.8 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 CRK31724.1 - 0.087 12.4 0.3 0.24 11.0 0.3 1.7 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain AdoHcyase PF05221.17 CRK31725.1 - 3.2e-127 423.8 0.0 2.6e-73 246.8 0.2 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 CRK31725.1 - 2.7e-83 277.9 2.9 4.2e-83 277.3 2.9 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 CRK31725.1 - 1.4e-06 27.8 0.2 3.8e-06 26.4 0.2 1.7 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 CRK31725.1 - 0.017 14.7 0.3 0.031 13.9 0.3 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain ELFV_dehydrog PF00208.21 CRK31725.1 - 0.059 13.1 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TrkA_N PF02254.18 CRK31725.1 - 0.1 12.9 0.1 0.22 11.8 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain Adeno_knob PF00541.17 CRK31726.1 - 0.0084 15.9 0.6 1.3 8.8 0.0 2.2 2 0 0 2 2 2 2 Adenoviral fibre protein (knob domain) DUF5513 PF17632.2 CRK31726.1 - 0.0098 16.3 0.0 9.3 6.7 0.0 2.5 2 0 0 2 2 2 2 Family of unknown function (DUF5513) Peptidase_M4 PF01447.18 CRK31726.1 - 0.036 14.6 0.4 1.6 9.2 0.0 2.5 2 0 0 2 2 2 0 Thermolysin metallopeptidase, catalytic domain FTO_CTD PF12934.7 CRK31726.1 - 0.038 13.8 0.9 4 7.2 0.2 2.3 2 0 0 2 2 2 0 FTO C-terminal domain DsrD PF08679.11 CRK31726.1 - 0.14 12.4 0.2 31 4.9 0.0 2.5 2 0 0 2 2 2 0 Dissimilatory sulfite reductase D (DsrD) Mito_carr PF00153.27 CRK31727.1 - 2.2e-41 139.7 3.7 1.1e-16 60.6 0.2 4.2 3 1 0 3 3 3 3 Mitochondrial carrier protein SesA PF17107.5 CRK31727.1 - 4.2e-26 91.5 0.4 3.1e-25 88.7 0.0 2.4 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases NACHT PF05729.12 CRK31727.1 - 7.8e-19 68.2 0.2 1.7e-18 67.1 0.2 1.5 1 0 0 1 1 1 1 NACHT domain WD40 PF00400.32 CRK31727.1 - 3.4e-16 59.3 1.4 8.2e-09 36.0 0.1 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK31727.1 - 5.3e-08 33.1 0.1 2.9e-05 24.3 0.0 2.6 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CRK31727.1 - 2.9e-06 26.5 0.5 0.0016 17.5 0.1 2.2 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CRK31727.1 - 0.00036 19.3 0.1 0.075 11.7 0.0 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 WD40_like PF17005.5 CRK31727.1 - 0.0038 16.6 0.0 0.006 15.9 0.0 1.2 1 0 0 1 1 1 1 WD40-like domain AAA_22 PF13401.6 CRK31727.1 - 0.017 15.4 0.1 0.69 10.2 0.0 3.6 4 0 0 4 4 4 0 AAA domain RNA_helicase PF00910.22 CRK31727.1 - 0.024 15.0 0.0 0.1 13.0 0.0 2.1 2 0 0 2 2 2 0 RNA helicase DUF769 PF05590.11 CRK31727.1 - 0.047 13.1 0.0 0.09 12.2 0.0 1.4 1 0 0 1 1 1 0 Xylella fastidiosa protein of unknown function (DUF769) AAA_19 PF13245.6 CRK31727.1 - 0.068 13.5 0.0 0.25 11.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 CRK31727.1 - 0.1 12.3 0.0 0.3 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mpv17_PMP22 PF04117.12 CRK31730.1 - 5.2e-21 74.6 0.2 5.2e-21 74.6 0.2 1.8 2 0 0 2 2 2 1 Mpv17 / PMP22 family CwfJ_C_2 PF04676.14 CRK31731.1 - 2.8e-26 92.3 0.1 2.8e-26 92.3 0.1 2.3 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.15 CRK31731.1 - 8.1e-19 67.7 0.0 1.5e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 ATP_bind_1 PF03029.17 CRK31733.1 - 2.5e-113 377.8 0.0 1.1e-71 241.4 0.0 2.1 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 CRK31733.1 - 5.4e-09 35.9 0.0 0.012 15.1 0.0 4.0 3 2 0 3 3 3 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 CRK31733.1 - 2.6e-05 23.8 0.1 0.35 10.4 0.0 3.1 3 0 0 3 3 3 2 Ferrous iron transport protein B MMR_HSR1 PF01926.23 CRK31733.1 - 3.6e-05 23.8 0.0 0.38 10.8 0.0 3.4 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_24 PF13479.6 CRK31733.1 - 0.00041 20.1 0.0 0.0014 18.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CRK31733.1 - 0.0014 18.9 0.0 0.0079 16.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CRK31733.1 - 0.0022 18.4 0.0 0.0061 16.9 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain Roc PF08477.13 CRK31733.1 - 0.0026 17.9 0.0 6.9 6.9 0.0 3.5 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase MeaB PF03308.16 CRK31733.1 - 0.0027 16.7 0.0 3.1 6.7 0.0 3.3 3 1 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB G-alpha PF00503.20 CRK31733.1 - 0.0038 16.4 0.1 0.77 8.8 0.0 3.2 3 0 0 3 3 3 1 G-protein alpha subunit AAA_33 PF13671.6 CRK31733.1 - 0.0042 17.3 0.3 0.024 14.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 CRK31733.1 - 0.01 15.4 0.2 0.28 10.7 0.1 2.9 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PRK PF00485.18 CRK31733.1 - 0.017 14.8 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family K1377 PF15352.6 CRK31733.1 - 0.023 13.0 2.1 2.3 6.4 0.6 2.1 2 0 0 2 2 2 0 Susceptibility to monomelic amyotrophy Arf PF00025.21 CRK31733.1 - 0.028 13.9 0.0 15 5.0 0.0 3.2 3 0 0 3 3 3 0 ADP-ribosylation factor family LpxB PF02684.15 CRK31733.1 - 0.038 12.8 0.6 6 5.6 0.1 2.2 2 0 0 2 2 2 0 Lipid-A-disaccharide synthetase NB-ARC PF00931.22 CRK31733.1 - 0.038 13.2 0.0 0.086 12.0 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain SRP54 PF00448.22 CRK31733.1 - 0.041 13.5 0.0 0.17 11.5 0.0 2.1 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain AAA_30 PF13604.6 CRK31733.1 - 0.043 13.5 0.0 0.077 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF5641 PF18701.1 CRK31733.1 - 0.054 13.7 0.3 8 6.7 0.2 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5641) IlvC PF01450.19 CRK31733.1 - 0.055 13.8 1.4 29 4.9 0.0 3.2 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, catalytic domain Thioredoxin_6 PF13848.6 CRK31733.1 - 0.058 13.3 0.1 18 5.2 0.0 2.6 2 0 0 2 2 2 0 Thioredoxin-like domain NACHT PF05729.12 CRK31733.1 - 0.074 13.0 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ApoC-I PF04691.12 CRK31733.1 - 0.12 12.3 2.6 19 5.3 0.1 3.3 3 0 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) BRF1 PF07741.13 CRK31733.1 - 0.13 12.6 4.3 1.5 9.2 1.6 2.8 3 0 0 3 3 2 0 Brf1-like TBP-binding domain Pox_A32 PF04665.12 CRK31733.1 - 0.6 9.5 1.8 1.9 7.9 0.0 2.5 3 0 0 3 3 3 0 Poxvirus A32 protein DUF780 PF05611.11 CRK31733.1 - 0.97 10.2 7.9 12 6.8 1.0 2.4 2 0 0 2 2 2 0 Caenorhabditis elegans protein of unknown function (DUF780) MttA_Hcf106 PF02416.16 CRK31733.1 - 7 6.1 8.0 13 5.2 0.2 3.3 4 0 0 4 4 4 0 mttA/Hcf106 family DNA_RNApol_7kD PF03604.13 CRK31734.1 - 3.4e-14 52.2 9.3 4.4e-14 51.9 9.3 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit GATA PF00320.27 CRK31734.1 - 0.008 15.8 0.2 0.008 15.8 0.2 2.2 1 1 1 2 2 2 1 GATA zinc finger Zn-ribbon_8 PF09723.10 CRK31734.1 - 0.017 15.2 2.2 0.032 14.4 2.2 1.4 1 0 0 1 1 1 0 Zinc ribbon domain HypA PF01155.19 CRK31734.1 - 0.031 14.3 1.2 0.038 14.0 1.2 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TF_Zn_Ribbon PF08271.12 CRK31734.1 - 0.13 11.8 5.9 0.47 10.0 0.1 2.2 1 1 1 2 2 2 0 TFIIB zinc-binding zf_UBZ PF18439.1 CRK31734.1 - 0.44 10.2 3.0 8.6 6.1 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger HIT PF01230.23 CRK31735.1 - 5.3e-18 65.6 0.0 9e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 CRK31735.1 - 3.2e-06 27.6 0.0 9.4e-06 26.1 0.0 1.6 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 CRK31735.1 - 3e-05 23.9 0.0 4.8e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 TetR_C_22 PF17928.1 CRK31735.1 - 0.074 13.4 1.5 2.3 8.5 0.4 2.3 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain SelA PF03841.13 CRK31735.1 - 0.12 11.3 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 L-seryl-tRNA selenium transferase DNA_RNApol_7kD PF03604.13 CRK31736.1 - 9.5e-14 50.8 9.3 1.8e-13 49.9 9.3 1.5 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit Aldo_ket_red PF00248.21 CRK31736.1 - 3e-06 26.6 0.0 3.6e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family GATA PF00320.27 CRK31736.1 - 0.024 14.2 0.2 0.024 14.2 0.2 2.2 1 1 1 2 2 2 0 GATA zinc finger zinc-ribbon_6 PF10005.9 CRK31736.1 - 0.043 14.5 0.3 0.076 13.7 0.3 1.4 1 0 0 1 1 1 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 CRK31736.1 - 0.06 13.5 2.2 0.12 12.5 2.2 1.5 1 0 0 1 1 1 0 Zinc ribbon domain HypA PF01155.19 CRK31736.1 - 0.12 12.4 1.4 0.21 11.6 1.4 1.4 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TF_Zn_Ribbon PF08271.12 CRK31736.1 - 1.1 8.8 6.4 1.3 8.6 0.1 2.4 1 1 1 2 2 2 0 TFIIB zinc-binding HIT PF01230.23 CRK31737.1 - 6.6e-18 65.3 0.0 1.2e-17 64.4 0.0 1.4 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 CRK31737.1 - 4.2e-06 27.2 0.0 1.3e-05 25.7 0.0 1.6 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 CRK31737.1 - 3.4e-05 23.7 0.0 6.4e-05 22.8 0.0 1.5 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 TetR_C_22 PF17928.1 CRK31737.1 - 0.081 13.3 1.5 2.3 8.5 0.4 2.2 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain SelA PF03841.13 CRK31737.1 - 0.12 11.3 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 L-seryl-tRNA selenium transferase Aldo_ket_red PF00248.21 CRK31738.1 - 7.6e-45 153.3 0.0 4.1e-43 147.7 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family UDPGT PF00201.18 CRK31738.1 - 0.078 11.8 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase UQ_con PF00179.26 CRK31739.1 - 5.8e-45 152.4 0.0 6.6e-45 152.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CRK31739.1 - 9.7e-07 28.5 0.0 1.5e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B Prok-E2_A PF14457.6 CRK31739.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family A Aldo_ket_red PF00248.21 CRK31740.1 - 2.9e-20 72.7 0.0 3.3e-20 72.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family UQ_con PF00179.26 CRK31741.1 - 1.6e-44 151.0 0.0 1.8e-44 150.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CRK31741.1 - 8.8e-07 28.7 0.0 1.3e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B Abhydrolase_1 PF00561.20 CRK31742.1 - 2.3e-09 37.3 0.0 6.7e-09 35.8 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CRK31742.1 - 2.7e-05 23.6 0.0 0.0023 17.3 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Med19 PF10278.9 CRK31742.1 - 0.014 15.3 0.9 0.014 15.3 0.9 2.0 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 Nop53 PF07767.11 CRK31743.1 - 0.34 10.2 27.6 0.56 9.5 27.6 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF3808 PF10300.9 CRK31744.1 - 2e-113 379.7 0.0 3.1e-113 379.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) RabGAP-TBC PF00566.18 CRK31744.1 - 1.9e-20 73.5 0.0 1.2e-16 61.1 0.0 3.3 2 1 0 2 2 2 1 Rab-GTPase-TBC domain TPR_5 PF12688.7 CRK31744.1 - 0.23 11.7 1.4 0.49 10.7 0.1 2.3 3 0 0 3 3 3 0 Tetratrico peptide repeat TPR_19 PF14559.6 CRK31744.1 - 0.55 10.8 6.5 0.13 12.8 0.8 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TFIIB PF00382.19 CRK31745.1 - 1.4e-26 92.3 0.1 1.9e-18 66.3 0.0 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 CRK31745.1 - 4.4 6.9 5.0 1 8.9 1.3 2.0 2 0 0 2 2 2 0 TFIIB zinc-binding DUF1349 PF07081.11 CRK31747.1 - 2.3e-23 82.9 0.0 2.8e-23 82.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) BTB PF00651.31 CRK31748.1 - 0.026 14.7 0.0 0.065 13.5 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain DUF4083 PF13314.6 CRK31750.1 - 1.2 9.1 4.4 6.2 6.8 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) MARVEL PF01284.23 CRK31750.1 - 1.8 8.6 9.4 15 5.6 9.4 2.0 1 1 0 1 1 1 0 Membrane-associating domain Bac_luciferase PF00296.20 CRK31751.1 - 1.6e-60 205.2 3.2 2e-60 204.8 3.2 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Amidohydro_2 PF04909.14 CRK31751.1 - 0.0063 16.3 0.1 0.35 10.6 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase Bac_luciferase PF00296.20 CRK31752.1 - 3.1e-36 125.4 1.8 3.6e-36 125.2 1.8 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase SSF PF00474.17 CRK31753.1 - 4.1e-19 68.7 32.2 4.1e-19 68.7 32.2 1.6 2 0 0 2 2 2 1 Sodium:solute symporter family DUF1772 PF08592.11 CRK31753.1 - 0.0023 18.2 4.5 0.0023 18.2 4.5 5.5 4 1 3 7 7 7 2 Domain of unknown function (DUF1772) Cutinase PF01083.22 CRK31754.1 - 6.1e-53 179.4 6.8 8.6e-53 178.9 6.8 1.2 1 0 0 1 1 1 1 Cutinase TauD PF02668.16 CRK31754.1 - 2.3e-51 175.2 0.0 3.3e-51 174.6 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CBM_1 PF00734.18 CRK31754.1 - 5.3e-09 35.9 16.4 5.3e-09 35.9 16.4 3.5 3 1 0 3 3 3 1 Fungal cellulose binding domain PE-PPE PF08237.11 CRK31754.1 - 3.5e-05 23.5 0.2 6.5e-05 22.6 0.2 1.4 1 0 0 1 1 1 1 PE-PPE domain CotH PF08757.11 CRK31754.1 - 0.0062 16.1 0.1 0.0089 15.6 0.1 1.1 1 0 0 1 1 1 1 CotH kinase protein Abhydrolase_1 PF00561.20 CRK31754.1 - 0.076 12.6 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold MFS_1 PF07690.16 CRK31756.1 - 1.6e-25 89.8 20.5 2.4e-25 89.2 20.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Aldo_ket_red PF00248.21 CRK31757.1 - 2.8e-67 227.0 0.0 4.2e-67 226.4 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Zn_clus PF00172.18 CRK31757.1 - 4.1e-08 33.2 8.6 7.9e-08 32.3 8.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 CRK31757.1 - 5.2e-07 29.0 0.0 1e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Tri3 PF07428.11 CRK31758.1 - 1.7e-05 23.9 0.1 4.1e-05 22.7 0.1 1.5 1 1 0 1 1 1 1 15-O-acetyltransferase Tri3 Ephrin_lbd PF01404.19 CRK31758.1 - 0.079 13.0 0.4 0.17 11.9 0.4 1.5 1 0 0 1 1 1 0 Ephrin receptor ligand binding domain p450 PF00067.22 CRK31759.1 - 2.3e-30 105.8 0.0 3.6e-29 101.8 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 GMC_oxred_N PF00732.19 CRK31760.1 - 3.8e-29 102.0 0.0 3.8e-28 98.7 0.0 2.1 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CRK31760.1 - 8.4e-13 49.1 0.0 2.1e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 CRK31760.1 - 9e-05 21.8 0.0 0.00017 20.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CRK31760.1 - 0.0021 18.3 0.0 0.005 17.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CRK31760.1 - 0.0078 15.3 0.1 0.02 14.0 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain ThiF PF00899.21 CRK31760.1 - 0.017 14.5 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 ThiF family FAD_binding_3 PF01494.19 CRK31760.1 - 0.036 13.3 0.2 0.086 12.1 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.12 CRK31760.1 - 0.074 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein MFS_1 PF07690.16 CRK31762.1 - 1.6e-29 102.9 37.6 1.6e-29 102.9 37.6 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF2613 PF11021.8 CRK31762.1 - 0.069 13.3 1.2 0.29 11.3 1.2 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) Chloroplast_duf PF14476.6 CRK31762.1 - 0.16 10.9 0.1 0.25 10.3 0.1 1.2 1 0 0 1 1 1 0 Petal formation-expressed PAP2_C PF14360.6 CRK31762.1 - 0.33 11.5 3.6 0.57 10.7 0.2 3.0 3 0 0 3 3 3 0 PAP2 superfamily C-terminal adh_short PF00106.25 CRK31763.1 - 4.7e-37 127.3 0.0 6.9e-37 126.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK31763.1 - 8.6e-25 87.6 0.0 1.1e-24 87.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 CRK31763.1 - 2.9e-06 26.9 0.0 0.00038 19.9 0.0 2.1 2 0 0 2 2 2 2 Fungal family of unknown function (DUF1776) KR PF08659.10 CRK31763.1 - 0.0011 18.9 0.0 0.0027 17.6 0.0 1.7 1 1 0 1 1 1 1 KR domain NmrA PF05368.13 CRK31763.1 - 0.0049 16.4 0.1 0.0078 15.8 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 CRK31763.1 - 0.099 12.1 0.1 0.16 11.4 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF3769 PF12600.8 CRK31767.1 - 0.071 12.0 0.0 0.084 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3769) Glyco_hydro_88 PF07470.13 CRK31768.1 - 1e-10 41.3 4.2 1.7e-10 40.5 4.2 1.5 1 1 0 1 1 1 1 Glycosyl Hydrolase Family 88 Fungal_trans PF04082.18 CRK31769.1 - 4.1e-13 49.0 0.1 4.9e-12 45.5 0.1 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK31769.1 - 3.2e-08 33.6 14.6 3.2e-08 33.6 14.6 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4381 PF14316.6 CRK31769.1 - 0.011 16.0 0.0 0.024 14.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) MFS_1 PF07690.16 CRK31770.1 - 1.1e-32 113.4 29.2 2.1e-32 112.5 26.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 CRK31770.1 - 1.4e-06 27.9 6.8 1.4e-06 27.9 6.8 2.5 2 1 1 3 3 3 1 Uncharacterised MFS-type transporter YbfB 2TM PF13239.6 CRK31770.1 - 0.58 10.5 0.1 0.58 10.5 0.1 4.6 3 2 1 4 4 4 0 2TM domain PhyH PF05721.13 CRK31771.1 - 5.8e-25 88.8 0.0 7.8e-25 88.4 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Pectate_lyase PF03211.13 CRK31772.1 - 1.5e-83 279.3 12.0 1.8e-83 279.1 12.0 1.0 1 0 0 1 1 1 1 Pectate lyase Transferase PF02458.15 CRK31773.1 - 8.2e-08 31.3 0.0 6e-07 28.5 0.0 2.0 1 1 0 1 1 1 1 Transferase family DHQ_synthase PF01761.20 CRK31775.1 - 1.3e-32 113.0 0.1 1.7e-32 112.7 0.1 1.1 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 CRK31775.1 - 2.6e-10 40.5 0.0 3.2e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.19 CRK31775.1 - 0.0062 15.4 0.0 0.0073 15.2 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DUF3826 PF12875.7 CRK31775.1 - 0.17 12.0 0.1 0.98 9.5 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3826) Methyltransf_3 PF01596.17 CRK31776.1 - 1.4e-17 63.6 0.0 1.7e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 CRK31776.1 - 2.4e-17 63.9 0.0 4.1e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain HTH_53 PF18606.1 CRK31776.1 - 0.011 15.4 0.0 0.037 13.7 0.0 1.8 2 0 0 2 2 2 0 Zap helix turn helix N-terminal domain CmcI PF04989.12 CRK31776.1 - 0.029 14.1 0.0 0.039 13.6 0.0 1.3 1 0 0 1 1 1 0 Cephalosporin hydroxylase Sugar_tr PF00083.24 CRK31777.1 - 3.4e-84 283.3 22.9 4.2e-84 283.0 22.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK31777.1 - 8.3e-18 64.4 39.3 7.9e-15 54.6 18.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 CRK31777.1 - 1.7e-06 27.1 3.5 1.7e-06 27.1 3.5 1.7 2 0 0 2 2 2 1 MFS_1 like family MFS_2 PF13347.6 CRK31777.1 - 8.6e-05 21.3 21.6 0.00021 20.0 3.8 3.1 3 0 0 3 3 3 2 MFS/sugar transport protein AA_permease_2 PF13520.6 CRK31778.1 - 2.7e-29 102.3 26.0 3.7e-29 101.8 26.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CRK31778.1 - 7e-15 54.6 19.5 1.1e-14 53.9 19.5 1.2 1 0 0 1 1 1 1 Amino acid permease YlaH PF14036.6 CRK31778.1 - 0.0027 18.0 1.4 0.0027 18.0 1.4 2.8 3 0 0 3 3 3 1 YlaH-like protein DUF4191 PF13829.6 CRK31778.1 - 0.017 14.4 2.0 0.021 14.2 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) HlyIII PF03006.20 CRK31778.1 - 9.6 5.8 15.0 0.43 10.3 0.5 2.9 2 1 1 3 3 3 0 Haemolysin-III related Acetyltransf_1 PF00583.25 CRK31779.1 - 6.4e-10 39.3 0.0 2.6e-09 37.3 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CRK31779.1 - 5.4e-07 30.0 0.0 9.4e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CRK31779.1 - 3.3e-06 27.1 0.0 5.5e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CRK31779.1 - 0.0038 17.2 0.0 0.0078 16.2 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 CRK31779.1 - 0.018 15.2 0.0 0.043 14.0 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 CRK31779.1 - 0.1 12.6 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SGL PF08450.12 CRK31780.1 - 3e-23 82.7 0.8 5.4e-23 81.9 0.8 1.5 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 CRK31780.1 - 0.0012 18.9 0.0 0.0062 16.6 0.0 2.1 1 1 0 1 1 1 1 Strictosidine synthase Arylesterase PF01731.20 CRK31780.1 - 0.0019 18.3 0.1 0.016 15.4 0.0 2.6 2 1 1 3 3 3 1 Arylesterase Kelch_3 PF13415.6 CRK31780.1 - 0.0096 16.2 1.1 24 5.4 0.3 4.0 3 1 1 4 4 4 1 Galactose oxidase, central domain NHL PF01436.21 CRK31780.1 - 0.14 12.3 2.0 39 4.6 0.0 3.6 3 0 0 3 3 3 0 NHL repeat Rep_1B PF17873.1 CRK31780.1 - 1.9 8.5 5.5 2.9 7.9 1.2 2.7 3 0 0 3 3 3 0 Replicase polyprotein 1ab PglL_A PF15864.5 CRK31781.1 - 0.0021 17.7 0.1 0.0068 16.1 0.1 1.9 1 0 0 1 1 1 1 Protein glycosylation ligase Fungal_trans PF04082.18 CRK31782.1 - 7.4e-13 48.1 0.8 1.5e-12 47.1 0.8 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK31782.1 - 5.7e-06 26.4 8.3 1.1e-05 25.5 8.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 CRK31783.1 - 8.6e-38 130.2 28.9 1.2e-36 126.3 28.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily ATPase_gene1 PF09527.10 CRK31783.1 - 0.026 14.7 5.5 0.026 14.7 5.5 4.4 3 2 1 4 4 4 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter EMC3_TMCO1 PF01956.16 CRK31783.1 - 0.088 12.5 1.8 0.85 9.3 0.0 2.9 3 0 0 3 3 3 0 Integral membrane protein EMC3/TMCO1-like DUF4164 PF13747.6 CRK31783.1 - 0.15 12.3 0.1 0.31 11.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Claudin_2 PF13903.6 CRK31783.1 - 1.4 8.6 9.2 0.79 9.4 0.7 3.2 3 0 0 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction Fungal_trans PF04082.18 CRK31784.1 - 3e-11 42.8 0.1 6.2e-11 41.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK31784.1 - 4.2e-08 33.2 10.4 1.3e-07 31.6 10.4 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AMP-binding PF00501.28 CRK31785.1 - 3.4e-68 230.2 0.0 4.5e-68 229.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CRK31785.1 - 1.2e-16 61.4 0.3 2.2e-16 60.6 0.3 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding_C_2 PF14535.6 CRK31785.1 - 0.098 13.0 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain DEAD PF00270.29 CRK31786.1 - 6.6e-45 153.0 0.0 5.4e-43 146.8 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CRK31786.1 - 1.2e-21 77.1 0.0 2.5e-20 72.9 0.0 2.7 3 1 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CRK31786.1 - 4.7e-07 30.0 0.0 1e-06 28.9 0.0 1.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 CRK31786.1 - 0.004 16.9 0.1 0.039 13.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain Helicase_RecD PF05127.14 CRK31786.1 - 0.0091 15.9 0.0 0.023 14.6 0.0 1.6 2 0 0 2 2 2 1 Helicase AAA_22 PF13401.6 CRK31786.1 - 0.012 15.9 0.2 0.27 11.5 0.5 2.6 2 1 0 2 2 2 0 AAA domain ERCC3_RAD25_C PF16203.5 CRK31786.1 - 0.059 12.6 0.0 0.096 11.9 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase DLH PF01738.18 CRK31787.1 - 6e-22 78.3 0.3 7.6e-22 77.9 0.3 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 CRK31787.1 - 0.14 11.8 0.0 0.31 10.7 0.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF4407 PF14362.6 CRK31788.1 - 0.085 12.2 14.0 0.1 11.9 12.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) NPV_P10 PF05531.12 CRK31788.1 - 0.9 10.0 7.3 5.3 7.6 0.3 3.0 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein 3HCDH_N PF02737.18 CRK31788.1 - 1.4 8.7 4.2 1.4 8.8 0.6 2.2 1 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF4201 PF13870.6 CRK31788.1 - 3.2 7.5 10.8 4.8 6.9 6.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) YlqD PF11068.8 CRK31788.1 - 4.2 7.7 8.1 3.6 8.0 0.8 2.5 2 0 0 2 2 2 0 YlqD protein DUF4337 PF14235.6 CRK31788.1 - 6.8 6.8 7.7 0.73 9.9 1.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) Glyco_hydro_10 PF00331.20 CRK31790.1 - 1.8e-88 296.7 0.1 8.2e-60 202.6 0.1 2.0 2 0 0 2 2 2 2 Glycosyl hydrolase family 10 Mito_carr PF00153.27 CRK31791.1 - 5.8e-39 131.9 6.4 3.5e-16 58.9 0.5 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein SAD_SRA PF02182.17 CRK31792.1 - 2.9e-35 121.3 0.0 4.5e-35 120.7 0.0 1.3 1 0 0 1 1 1 1 SAD/SRA domain V-SNARE_C PF12352.8 CRK31793.1 - 2.4e-14 53.3 0.1 7.6e-14 51.7 0.1 1.9 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sigma70_r4 PF04545.16 CRK31793.1 - 0.0071 15.8 0.0 0.022 14.3 0.0 1.9 1 0 0 1 1 1 1 Sigma-70, region 4 Sec20 PF03908.13 CRK31793.1 - 0.013 15.4 0.0 0.055 13.4 0.0 1.9 2 0 0 2 2 2 0 Sec20 KxDL PF10241.9 CRK31793.1 - 0.016 15.4 0.3 6.7 7.1 0.1 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein DivIC PF04977.15 CRK31793.1 - 2.6 7.9 5.5 5.3 6.9 0.1 3.5 3 1 0 4 4 4 0 Septum formation initiator TPR_MLP1_2 PF07926.12 CRK31793.1 - 4 7.5 7.3 1.3 9.1 1.1 2.6 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein TPK_B1_binding PF04265.14 CRK31794.1 - 3.5e-22 77.9 0.2 5.7e-22 77.2 0.2 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain TPK_catalytic PF04263.16 CRK31794.1 - 1.6e-19 70.1 0.0 2.3e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain DUF5353 PF17304.2 CRK31796.1 - 2e-14 53.1 5.4 3.9e-14 52.2 5.4 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5353) CHCH PF06747.13 CRK31796.1 - 1.6e-06 28.1 3.4 2.5e-06 27.5 3.4 1.3 1 0 0 1 1 1 1 CHCH domain LEA_4 PF02987.16 CRK31796.1 - 0.00036 20.6 14.9 0.00036 20.6 14.9 2.4 2 0 0 2 2 2 1 Late embryogenesis abundant protein DUF45 PF01863.17 CRK31796.1 - 1.1 9.2 3.3 4.8 7.2 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF45 GCK PF07802.11 CRK31796.1 - 1.2 9.6 7.2 0.093 13.2 1.0 2.4 2 0 0 2 2 2 0 GCK domain Myb_DNA-bind_3 PF12776.7 CRK31797.1 - 1.3e-25 90.2 0.7 1.3e-25 90.2 0.7 2.2 2 0 0 2 2 1 1 Myb/SANT-like DNA-binding domain EIF4E-T PF10477.9 CRK31797.1 - 0.0014 17.6 9.0 0.0018 17.2 9.0 1.1 1 0 0 1 1 1 1 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E EPL1 PF10513.9 CRK31797.1 - 0.055 13.8 3.7 0.11 12.9 3.7 1.6 1 0 0 1 1 1 0 Enhancer of polycomb-like Neur_chan_memb PF02932.16 CRK31797.1 - 0.057 13.5 2.9 0.076 13.1 2.9 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MCU PF04678.13 CRK31797.1 - 0.073 13.2 3.5 0.17 12.0 3.5 1.6 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Spt20 PF12090.8 CRK31797.1 - 0.098 12.3 30.6 0.17 11.5 30.6 1.3 1 0 0 1 1 1 0 Spt20 family TERB2 PF15101.6 CRK31797.1 - 0.12 12.4 11.6 0.22 11.5 11.6 1.4 1 0 0 1 1 1 0 Telomere-associated protein TERB2 RR_TM4-6 PF06459.12 CRK31797.1 - 0.25 11.1 5.3 0.5 10.1 5.3 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 CRK31797.1 - 0.28 9.9 7.7 0.37 9.5 7.7 1.2 1 0 0 1 1 1 0 Presenilin CPSF100_C PF13299.6 CRK31797.1 - 0.32 11.2 4.4 0.74 10.0 4.4 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SpoIIP PF07454.11 CRK31797.1 - 0.34 10.3 7.5 0.52 9.7 7.5 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Endostatin PF06482.11 CRK31797.1 - 0.74 9.2 10.7 1.3 8.5 10.7 1.3 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin PAT1 PF09770.9 CRK31797.1 - 2.1 6.5 25.9 2.8 6.1 25.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 eIF-3_zeta PF05091.12 CRK31797.1 - 3.1 6.7 12.0 4.5 6.1 12.0 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) MAJIN PF15077.6 CRK31797.1 - 3.6 7.3 9.9 6.7 6.4 9.9 1.4 1 0 0 1 1 1 0 Membrane-anchored junction protein Sarcoglycan_2 PF05510.13 CRK31797.1 - 3.7 6.2 7.0 5.8 5.6 7.0 1.2 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon DUF719 PF05334.13 CRK31797.1 - 5.8 7.1 9.9 7.3 6.7 7.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF719) Roughex PF06020.11 CRK31797.1 - 6.7 5.7 14.4 12 4.8 14.4 1.4 1 0 0 1 1 1 0 Drosophila roughex protein UPF0560 PF10577.9 CRK31797.1 - 8.3 4.8 18.7 12 4.2 18.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Hid1 PF12722.7 CRK31797.1 - 8.5 4.4 8.7 11 4.1 8.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein ACT_7 PF13840.6 CRK31800.1 - 1.2e-23 82.7 0.1 2.7e-17 62.3 0.0 2.4 2 0 0 2 2 2 2 ACT domain FAT PF02259.23 CRK31801.1 - 2.2e-71 240.9 6.9 7.4e-71 239.2 6.9 2.0 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 CRK31801.1 - 6.9e-32 111.2 2.4 1.1e-31 110.5 0.3 2.6 3 0 0 3 3 3 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 CRK31801.1 - 3.7e-08 33.0 0.2 1e-07 31.6 0.2 1.9 1 0 0 1 1 1 1 FATC domain TPR_8 PF13181.6 CRK31801.1 - 0.024 14.8 3.6 0.061 13.6 0.2 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA_32 PF13654.6 CRK31801.1 - 0.03 13.1 0.6 0.099 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain TPR_2 PF07719.17 CRK31801.1 - 0.075 13.2 5.2 5.1 7.5 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 CRK31801.1 - 0.83 9.6 5.4 14 5.7 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 CRK31801.1 - 9.8 7.1 6.7 20 6.1 0.5 4.4 3 0 0 3 3 3 0 Tetratricopeptide repeat GGACT PF06094.12 CRK31802.1 - 5.5e-20 72.2 0.0 7.1e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like DUF4932 PF16286.5 CRK31802.1 - 0.0037 16.6 0.0 0.0048 16.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4932) MFS_1 PF07690.16 CRK31803.1 - 5.6e-07 28.8 11.5 3.9e-06 26.0 2.1 2.3 2 1 1 3 3 3 2 Major Facilitator Superfamily Mito_carr PF00153.27 CRK31804.1 - 8e-43 144.3 1.3 1.2e-16 60.3 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CRK31804.1 - 0.032 13.4 1.3 0.45 9.6 0.1 2.9 2 1 0 3 3 3 0 Gammaproteobacterial serine protease Fungal_trans PF04082.18 CRK31805.1 - 3.9e-22 78.5 0.0 4.3e-22 78.4 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3629 PF12302.8 CRK31805.1 - 0.13 11.6 0.0 0.18 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3629) Pkinase PF00069.25 CRK31820.1 - 8.4e-47 159.7 0.0 1.1e-46 159.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK31820.1 - 9.8e-24 84.0 0.0 1.2e-23 83.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CRK31820.1 - 0.0013 17.7 0.0 0.0018 17.3 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CRK31820.1 - 0.0018 18.2 0.0 0.0023 17.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 CRK31820.1 - 0.0021 17.5 0.0 0.0034 16.8 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 CRK31820.1 - 0.0036 16.4 0.0 0.0051 15.9 0.0 1.1 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.14 CRK31820.1 - 0.12 11.7 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L28e PF01778.17 CRK31823.1 - 2.3e-27 96.0 0.6 3.3e-27 95.5 0.1 1.5 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 CRK31823.1 - 1.5e-22 80.0 1.0 2.7e-22 79.3 1.0 1.4 1 0 0 1 1 1 1 Mak16 protein C-terminal region Reovirus_cap PF00979.17 CRK31823.1 - 0.13 11.4 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 Reovirus outer capsid protein, Sigma 3 His_Phos_1 PF00300.22 CRK31826.1 - 1.1e-10 41.6 0.0 8.4e-08 32.1 0.0 2.1 1 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Arrestin_N PF00339.29 CRK31833.1 - 1.1e-05 25.5 0.0 5.7e-05 23.2 0.0 2.0 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Bul1_N PF04425.12 CRK31833.1 - 0.033 13.0 0.1 0.21 10.3 0.1 2.1 1 1 1 2 2 2 0 Bul1 N terminus DUF5313 PF17240.2 CRK31833.1 - 0.054 13.9 0.1 0.084 13.3 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5313) Aldedh PF00171.22 CRK31839.1 - 1.7e-28 99.4 0.1 1.9e-28 99.2 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RHD3 PF05879.12 CRK31841.1 - 2.2e-65 221.2 0.0 2.5e-65 221.1 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) Clr2 PF10383.9 CRK31842.1 - 2e-17 64.3 0.0 1.6e-16 61.4 0.0 2.3 2 1 0 2 2 2 1 Transcription-silencing protein Clr2 Clr2_transil PF16761.5 CRK31842.1 - 1.5e-06 28.9 3.3 3.8e-06 27.6 3.3 1.7 1 1 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 HypA PF01155.19 CRK31843.1 - 0.055 13.5 0.2 0.055 13.5 0.2 3.4 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Phage_GPO PF05929.11 CRK31843.1 - 0.21 11.2 3.9 0.31 10.6 3.9 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Ndc1_Nup PF09531.10 CRK31843.1 - 3.6 6.2 4.6 3.8 6.1 4.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup zf-C2H2_6 PF13912.6 CRK31843.1 - 7.3 6.7 11.4 1.1 9.3 0.1 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger F-box-like PF12937.7 CRK31844.1 - 1.8e-08 34.1 0.1 4.2e-08 33.0 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CRK31844.1 - 6.5e-08 32.3 0.0 2.4e-07 30.5 0.0 1.9 2 0 0 2 2 2 1 F-box domain UIM PF02809.20 CRK31844.1 - 0.077 13.0 13.1 0.018 14.9 6.0 2.8 2 0 0 2 2 2 0 Ubiquitin interaction motif PCNA_N PF00705.18 CRK31847.1 - 1.3e-53 180.0 3.1 1.8e-53 179.6 3.1 1.1 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 CRK31847.1 - 3.1e-08 33.8 0.1 1.7e-06 28.2 0.0 2.1 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Hus1 PF04005.12 CRK31847.1 - 3.6e-05 23.0 0.1 4.2e-05 22.8 0.1 1.1 1 0 0 1 1 1 1 Hus1-like protein Rad9 PF04139.13 CRK31847.1 - 3.7e-05 23.3 0.0 5.3e-05 22.8 0.0 1.3 1 1 0 1 1 1 1 Rad9 HLH PF00010.26 CRK31847.1 - 0.065 13.2 0.2 0.1 12.5 0.2 1.3 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain Pkinase PF00069.25 CRK31850.1 - 7e-05 22.3 0.0 8.5e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain DUF4752 PF15944.5 CRK31850.1 - 0.098 12.7 0.0 0.27 11.3 0.0 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4752) DUF3931 PF13082.6 CRK31850.1 - 0.14 12.4 0.0 0.36 11.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3931) Ldh_1_N PF00056.23 CRK31852.1 - 2e-27 96.0 0.2 2.7e-27 95.6 0.2 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 CRK31852.1 - 5.6e-23 81.7 0.0 8.8e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain ATG13 PF10033.9 CRK31853.1 - 5e-17 62.4 0.4 5.7e-17 62.2 0.4 1.0 1 0 0 1 1 1 1 Autophagy-related protein 13 Fer4_13 PF13370.6 CRK31856.1 - 3.2 8.3 4.7 22 5.7 0.0 3.9 3 2 1 4 4 4 0 4Fe-4S single cluster domain of Ferredoxin I RNA_pol_N PF01194.17 CRK31857.1 - 5.4e-31 106.7 0.9 6.3e-31 106.5 0.9 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.12 CRK31857.1 - 0.11 12.7 0.5 0.21 11.8 0.5 1.5 1 1 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) WD40 PF00400.32 CRK31858.1 - 4.7e-09 36.7 12.4 0.0016 19.2 0.4 6.1 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK31858.1 - 1e-05 25.7 0.1 0.042 14.2 0.1 4.0 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Peptidase_S9_N PF02897.15 CRK31858.1 - 0.0019 17.0 0.1 0.92 8.2 0.0 2.7 3 0 0 3 3 3 2 Prolyl oligopeptidase, N-terminal beta-propeller domain VPS9 PF02204.18 CRK31859.1 - 1.8e-29 102.0 0.0 3.2e-29 101.2 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 CRK31859.1 - 2.2e-16 59.9 0.0 5.1e-16 58.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) CUE PF02845.16 CRK31859.1 - 1.8e-10 40.3 0.1 1.5e-09 37.4 0.0 2.3 2 0 0 2 2 2 1 CUE domain YppG PF14179.6 CRK31859.1 - 4.1 8.1 7.7 6.2 7.6 0.2 3.5 3 0 0 3 3 3 0 YppG-like protein Cutinase PF01083.22 CRK31860.1 - 3.2e-42 144.5 0.0 4.5e-42 144.0 0.0 1.2 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 CRK31860.1 - 0.00054 19.6 0.0 0.00091 18.8 0.0 1.4 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_2 PF02230.16 CRK31860.1 - 0.0079 16.0 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 CRK31860.1 - 0.066 13.8 2.6 0.1 13.1 2.5 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF1654 PF07867.11 CRK31862.1 - 0.076 12.8 0.1 0.1 12.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1654) Sugar_tr PF00083.24 CRK31863.1 - 3.1e-22 79.1 0.3 3.3e-22 79.0 0.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK31863.1 - 7.5e-08 31.7 2.5 7.6e-08 31.7 2.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily PSP1 PF04468.12 CRK31864.1 - 2.4e-08 34.2 1.6 2.4e-08 34.1 0.6 1.5 2 0 0 2 2 2 1 PSP1 C-terminal conserved region Sulfatase PF00884.23 CRK31866.1 - 3.6e-07 29.9 0.0 4.5e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 CRK31866.1 - 0.019 14.6 0.1 0.019 14.6 0.1 1.2 1 1 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase PH_10 PF15411.6 CRK31867.1 - 2.7e-16 59.9 0.9 3.9e-16 59.4 0.9 1.2 1 0 0 1 1 1 1 Pleckstrin homology domain Anophelin PF10731.9 CRK31867.1 - 0.16 11.9 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito A_deaminase PF00962.22 CRK31868.1 - 3.4e-42 145.0 0.0 3.7e-42 144.8 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase TPR_12 PF13424.6 CRK31869.1 - 1.3e-10 41.4 15.6 6.3e-07 29.6 0.0 5.9 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 CRK31869.1 - 6.1e-06 26.0 12.7 0.84 9.9 0.6 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_10 PF13374.6 CRK31869.1 - 2.2e-05 24.2 11.1 0.56 10.1 0.2 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 CRK31869.1 - 0.00022 21.8 4.6 4.1 8.1 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 CRK31869.1 - 0.00035 21.1 15.0 1 10.4 0.3 6.7 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 CRK31869.1 - 0.0004 20.1 2.9 3.1 7.8 0.2 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 CRK31869.1 - 0.00089 19.1 5.1 6.4 7.0 0.0 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 CRK31869.1 - 0.21 11.9 8.3 12 6.4 0.1 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 CRK31869.1 - 2.7 8.9 5.8 68 4.5 0.1 5.1 4 1 0 4 4 4 0 Tetratricopeptide repeat ApbA_C PF08546.11 CRK31870.1 - 2.5e-29 102.0 0.0 4.9e-29 101.1 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 CRK31870.1 - 2.1e-20 72.9 0.0 4.3e-20 71.9 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA MOZART1 PF12554.8 CRK31870.1 - 0.0077 16.0 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated Glyco_hydro_85 PF03644.13 CRK31870.1 - 0.085 12.3 0.0 0.37 10.2 0.0 1.9 2 0 0 2 2 2 0 Glycosyl hydrolase family 85 U6-snRNA_bdg PF10596.9 CRK31871.1 - 2.7e-85 284.2 2.3 5.2e-58 195.5 0.2 3.2 3 0 0 3 3 3 2 U6-snRNA interacting domain of PrP8 U5_2-snRNA_bdg PF10597.9 CRK31871.1 - 5.1e-72 240.2 0.1 9.2e-72 239.4 0.1 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 Hom_end_hint PF05203.16 CRK31871.1 - 1.5e-08 34.8 0.0 2.9e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Hom_end-associated Hint Hom_end PF05204.14 CRK31871.1 - 0.00011 22.4 0.0 0.015 15.4 0.0 3.0 3 0 0 3 3 3 1 Homing endonuclease Myb_DNA-bind_6 PF13921.6 CRK31871.1 - 0.0017 18.6 0.1 0.0059 16.8 0.1 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain AtuA PF07287.11 CRK31871.1 - 0.16 10.6 0.0 0.27 9.9 0.0 1.2 1 0 0 1 1 1 0 Acyclic terpene utilisation family protein AtuA Hint_2 PF13403.6 CRK31871.1 - 0.17 12.2 0.0 3.3 8.0 0.0 2.5 1 1 0 1 1 1 0 Hint domain LAGLIDADG_3 PF14528.6 CRK31871.1 - 0.3 11.5 0.7 3.8 7.9 0.0 3.0 4 0 0 4 4 4 0 LAGLIDADG-like domain Sortilin_C PF15901.5 CRK31872.1 - 4.3e-09 36.9 0.3 5.5e-09 36.6 0.3 1.1 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, C-terminal DUF2561 PF10812.8 CRK31872.1 - 0.002 18.2 3.9 0.0036 17.4 3.9 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2561) CP12 PF02672.15 CRK31872.1 - 0.16 12.7 0.1 0.28 12.0 0.1 1.4 1 0 0 1 1 1 0 CP12 domain Rap_GAP PF02145.15 CRK31876.1 - 2.5e-28 98.9 0.0 3e-28 98.6 0.0 1.0 1 0 0 1 1 1 1 Rap/ran-GAP Glyco_hydro_47 PF01532.20 CRK31882.1 - 3.6e-117 392.1 0.0 1.2e-60 205.7 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 47 Pribosyltran PF00156.27 CRK31883.1 - 2.9e-09 36.6 0.1 4.3e-09 36.1 0.1 1.3 1 1 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CRK31883.1 - 0.001 18.5 0.0 0.0014 18.1 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 CRK31884.1 - 7.4e-16 58.1 0.0 1e-15 57.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CRK31884.1 - 0.0015 18.0 0.0 0.0022 17.4 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Rif1_N PF12231.8 CRK31886.1 - 7.5e-60 202.9 0.0 8.3e-60 202.7 0.0 1.0 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal AIP3 PF03915.13 CRK31888.1 - 2.7e-30 105.8 3.6 3.4e-30 105.4 3.6 1.1 1 0 0 1 1 1 1 Actin interacting protein 3 Lsr2 PF11774.8 CRK31888.1 - 0.11 12.6 1.4 0.22 11.7 0.9 1.7 1 1 0 1 1 1 0 Lsr2 Helicase_C PF00271.31 CRK31889.1 - 2.1e-10 40.9 0.0 3.7e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain MTP18 PF10558.9 CRK31891.1 - 1.3e-40 139.1 0.0 1.6e-40 138.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) zf-AN1 PF01428.16 CRK31892.1 - 5.3e-25 87.3 25.0 2.2e-12 46.9 6.8 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger Remorin_C PF03763.13 CRK31892.1 - 0.015 15.1 0.2 0.015 15.1 0.2 1.6 2 0 0 2 2 2 0 Remorin, C-terminal region IBR PF01485.21 CRK31892.1 - 0.017 15.3 4.0 0.017 15.3 4.0 2.6 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain Transp_Tc5_C PF04236.15 CRK31892.1 - 0.13 12.6 15.2 1.6 9.2 6.2 2.3 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain DpnI PF06044.12 CRK31892.1 - 0.69 9.5 2.4 3.8 7.1 0.5 2.3 2 0 0 2 2 2 0 Dam-replacing family Rad4 PF03835.15 CRK31893.1 - 1.1e-31 109.4 0.0 1.1e-31 109.4 0.0 2.2 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 CRK31893.1 - 5.5e-27 94.0 0.5 1.3e-26 92.7 0.5 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 CRK31893.1 - 1.9e-18 66.0 0.1 3.8e-18 65.0 0.1 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 CRK31893.1 - 4.6e-15 56.3 0.2 4.6e-15 56.3 0.2 6.3 7 0 0 7 7 7 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 CRK31893.1 - 0.002 18.6 0.3 0.0097 16.4 0.1 2.3 2 1 0 2 2 2 1 Transglutaminase-like superfamily RhoGEF PF00621.20 CRK31895.1 - 1.3e-39 136.3 0.2 9.6e-23 81.4 0.0 2.5 2 0 0 2 2 2 2 RhoGEF domain DUF3507 PF12015.8 CRK31895.1 - 0.0012 18.6 0.0 0.0025 17.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) RL PF17797.1 CRK31895.1 - 0.22 11.5 0.3 19 5.3 0.0 2.4 2 0 0 2 2 2 0 RL domain BCDHK_Adom3 PF10436.9 CRK31898.1 - 6.1e-40 136.7 0.1 6.2e-40 136.7 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase Myb_DNA-bind_4 PF13837.6 CRK31899.1 - 0.011 16.1 0.3 0.011 16.1 0.3 1.7 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Hus1 PF04005.12 CRK31900.1 - 3.2e-46 157.8 0.0 3.6e-46 157.6 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein RSN1_7TM PF02714.15 CRK31912.1 - 2.9e-27 95.7 0.8 2.9e-27 95.7 0.8 1.6 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_ext PF12621.8 CRK31912.1 - 1.3e-25 89.4 0.1 1.9e-25 88.8 0.1 1.3 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter B3_4 PF03483.17 CRK31914.1 - 1.5e-08 34.5 0.0 2.1e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 B3/4 domain RHS PF03527.14 CRK31914.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 RHS protein DUF3277 PF11681.8 CRK31915.1 - 0.54 10.1 2.0 13 5.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3277) Peroxidase_2 PF01328.17 CRK31917.1 - 1.9e-45 155.7 0.0 4.1e-45 154.6 0.0 1.5 1 0 0 1 1 1 1 Peroxidase, family 2 DPM3 PF08285.11 CRK31917.1 - 8.6e-34 115.6 0.2 1.6e-33 114.8 0.2 1.4 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF4407 PF14362.6 CRK31921.1 - 0.44 9.8 1.6 0.89 8.8 1.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Oxidored-like PF09791.9 CRK31922.1 - 1.5e-24 85.4 1.8 1.5e-24 85.4 1.8 2.4 2 0 0 2 2 2 1 Oxidoreductase-like protein, N-terminal DUF5522 PF17653.1 CRK31922.1 - 0.21 11.6 1.3 0.42 10.6 1.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5522) DUF3808 PF10300.9 CRK31923.1 - 1.1e-33 116.7 0.0 1.3e-33 116.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) SSB PF00436.25 CRK31925.1 - 0.33 11.0 2.6 0.38 10.8 2.6 1.0 1 0 0 1 1 1 0 Single-strand binding protein family DHO_dh PF01180.21 CRK31927.1 - 1.3e-15 57.4 0.0 1.2e-14 54.3 0.0 1.9 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase NMO PF03060.15 CRK31927.1 - 0.012 15.1 0.8 0.015 14.7 0.8 1.1 1 0 0 1 1 1 0 Nitronate monooxygenase IGPS PF00218.21 CRK31927.1 - 0.26 10.4 0.0 0.43 9.7 0.0 1.2 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase Thoc2 PF11732.8 CRK31928.1 - 1.2e-22 79.8 0.1 1.6e-22 79.3 0.1 1.2 1 0 0 1 1 1 1 Transcription- and export-related complex subunit THOC2_N PF16134.5 CRK31928.1 - 0.00043 19.0 0.3 0.00089 18.0 0.2 1.5 2 0 0 2 2 2 1 THO complex subunit 2 N-terminus Copper-fist PF00649.18 CRK31931.1 - 8.3e-19 66.8 0.7 1.6e-18 65.9 0.7 1.5 1 0 0 1 1 1 1 Copper fist DNA binding domain Methyltransf_16 PF10294.9 CRK31932.1 - 2.7e-15 56.5 0.0 3.6e-15 56.1 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 CRK31932.1 - 0.00027 20.4 0.0 0.00038 19.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 CRK31932.1 - 0.0068 17.1 0.1 0.019 15.6 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CRK31932.1 - 0.016 15.0 0.0 0.021 14.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 CRK31932.1 - 0.017 14.8 0.0 0.027 14.1 0.0 1.4 1 1 0 1 1 1 0 Conserved hypothetical protein 95 GidB PF02527.15 CRK31932.1 - 0.048 13.0 0.0 0.074 12.4 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G TFIIA PF03153.13 CRK31933.1 - 0.048 13.6 11.4 0.057 13.4 11.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf_C2H2_6 PF18450.1 CRK31933.1 - 0.15 11.8 1.0 0.29 10.9 1.0 1.4 1 0 0 1 1 1 0 Zinc Finger domain zf-H2C2_2 PF13465.6 CRK31933.1 - 0.22 12.0 3.2 1.6 9.3 0.7 2.5 2 0 0 2 2 2 0 Zinc-finger double domain Macoilin PF09726.9 CRK31933.1 - 2.5 6.6 5.6 3 6.3 5.6 1.1 1 0 0 1 1 1 0 Macoilin family PAT1 PF09770.9 CRK31933.1 - 5.9 5.0 13.9 6.6 4.9 13.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2461 PF09365.10 CRK31934.1 - 5.7e-45 153.8 0.0 6.7e-45 153.6 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) PARM PF17061.5 CRK31936.1 - 2.6 8.1 15.1 3.1 7.9 15.1 1.1 1 0 0 1 1 1 0 PARM Sugar_tr PF00083.24 CRK31937.1 - 7.7e-09 34.9 6.6 9e-09 34.7 6.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK31937.1 - 2.9e-05 23.2 7.5 3.7e-05 22.8 7.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Frag1 PF10277.9 CRK31937.1 - 0.069 12.7 11.8 0.17 11.4 11.8 1.7 1 1 0 1 1 1 0 Frag1/DRAM/Sfk1 family EMP70 PF02990.16 CRK31938.1 - 3.2e-47 161.4 0.2 3.8e-47 161.1 0.2 1.0 1 0 0 1 1 1 1 Endomembrane protein 70 Pkinase PF00069.25 CRK31939.1 - 1.2e-31 110.1 0.0 1.3e-31 110.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK31939.1 - 4.7e-11 42.5 0.0 5.3e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CRK31939.1 - 0.0046 16.9 0.0 0.0069 16.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CRK31939.1 - 0.0068 16.0 0.2 0.016 14.8 0.1 1.6 1 1 1 2 2 2 1 Choline/ethanolamine kinase RIO1 PF01163.22 CRK31939.1 - 0.023 14.3 0.1 0.038 13.6 0.1 1.4 1 1 0 1 1 1 0 RIO1 family Kdo PF06293.14 CRK31939.1 - 0.16 11.3 0.1 0.24 10.8 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Gtr1_RagA PF04670.12 CRK31942.1 - 5.4e-61 205.9 0.0 5.9e-61 205.8 0.0 1.0 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CRK31942.1 - 8.7e-07 29.0 0.0 1e-06 28.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 CRK31942.1 - 1.3e-06 28.6 0.0 1.8e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CRK31942.1 - 2.5e-06 27.2 0.0 2.8e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Arf PF00025.21 CRK31942.1 - 1.3e-05 24.7 0.0 1.5e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CRK31942.1 - 0.19 11.6 0.4 9.7 6.1 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase G-alpha PF00503.20 CRK31942.1 - 0.23 10.6 0.7 0.39 9.8 0.0 1.6 1 1 1 2 2 2 0 G-protein alpha subunit Ribosomal_L27A PF00828.19 CRK31943.1 - 3.3e-16 60.1 0.3 5e-16 59.5 0.3 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DUF4777 PF16007.5 CRK31943.1 - 0.14 12.4 0.0 0.34 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4777) Helicase_C PF00271.31 CRK31944.1 - 5.2e-15 55.8 0.0 8.3e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF3275 PF11679.8 CRK31945.1 - 0.33 10.9 2.4 0.48 10.4 1.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3275) ADH_N PF08240.12 CRK31946.1 - 3e-19 68.9 1.9 4.8e-19 68.3 1.9 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CRK31946.1 - 9.8e-10 38.5 0.2 1.7e-09 37.7 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 CRK31946.1 - 2.8e-05 23.6 0.0 5.3e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 CRK31946.1 - 0.00021 20.7 0.2 0.00033 20.0 0.2 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_25 PF13649.6 CRK31946.1 - 0.0048 17.6 0.2 0.0099 16.6 0.2 1.5 1 0 0 1 1 1 1 Methyltransferase domain PglD_N PF17836.1 CRK31946.1 - 0.018 15.7 1.1 0.1 13.3 0.6 2.3 2 0 0 2 2 2 0 PglD N-terminal domain 3HCDH_N PF02737.18 CRK31946.1 - 0.026 14.4 0.4 0.04 13.8 0.4 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CMAS PF02353.20 CRK31946.1 - 0.031 13.6 0.3 0.051 12.9 0.3 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase IlvN PF07991.12 CRK31946.1 - 0.035 13.7 0.1 0.054 13.1 0.1 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Methyltransf_11 PF08241.12 CRK31946.1 - 0.046 14.4 0.1 0.11 13.1 0.1 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 CRK31946.1 - 0.076 12.8 0.2 0.15 11.8 0.2 1.4 1 0 0 1 1 1 0 Methyltransferase domain TrkA_N PF02254.18 CRK31946.1 - 0.099 12.9 0.1 0.17 12.2 0.1 1.3 1 0 0 1 1 1 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 CRK31946.1 - 0.15 11.6 0.1 0.22 11.1 0.1 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ThiF PF00899.21 CRK31946.1 - 0.4 10.0 4.3 0.08 12.3 0.7 1.6 2 0 0 2 2 2 0 ThiF family Erf4 PF10256.9 CRK31947.1 - 0.13 12.4 0.0 0.39 10.8 0.0 1.8 1 1 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family PHO4 PF01384.20 CRK31948.1 - 2.3e-108 362.2 10.9 3e-108 361.9 10.9 1.1 1 0 0 1 1 1 1 Phosphate transporter family AFOR_N PF02730.15 CRK31948.1 - 0.036 13.9 0.5 0.075 12.9 0.5 1.5 1 0 0 1 1 1 0 Aldehyde ferredoxin oxidoreductase, N-terminal domain AAA PF00004.29 CRK31949.1 - 2.5e-15 57.1 0.0 6.6e-15 55.7 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CRK31949.1 - 0.00034 20.9 0.1 0.00086 19.6 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CRK31949.1 - 0.0008 19.8 0.6 0.0034 17.8 0.6 2.0 1 1 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.9 CRK31949.1 - 0.00083 18.7 0.0 0.0013 18.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.14 CRK31949.1 - 0.00094 19.2 0.1 0.0064 16.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) DnaB_C PF03796.15 CRK31949.1 - 0.019 14.3 0.0 0.034 13.5 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Mg_chelatase PF01078.21 CRK31949.1 - 0.022 14.1 0.0 0.039 13.3 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 CRK31949.1 - 0.027 15.0 0.0 0.09 13.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 CRK31949.1 - 0.059 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin KTI12 PF08433.10 CRK31949.1 - 0.061 12.8 0.3 0.1 12.0 0.3 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 NACHT PF05729.12 CRK31949.1 - 0.097 12.6 0.1 0.36 10.7 0.1 2.0 1 1 0 1 1 1 0 NACHT domain Zot PF05707.12 CRK31949.1 - 0.19 11.3 0.0 0.6 9.7 0.0 1.8 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) ATPase PF06745.13 CRK31949.1 - 0.35 10.2 1.1 0.64 9.3 0.2 1.8 2 0 0 2 2 2 0 KaiC AAA_33 PF13671.6 CRK31949.1 - 0.91 9.7 3.0 2.8 8.1 0.0 2.5 1 1 0 2 2 2 0 AAA domain tRNA-synt_2 PF00152.20 CRK31954.1 - 5.7e-35 120.9 0.0 6.2e-35 120.8 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) Acyl_transf_1 PF00698.21 CRK31955.1 - 1.5e-21 77.2 0.0 1.8e-21 77.0 0.0 1.1 1 0 0 1 1 1 1 Acyl transferase domain MaoC_dehydratas PF01575.19 CRK31955.1 - 0.00037 20.0 0.1 0.00059 19.4 0.1 1.3 1 0 0 1 1 1 1 MaoC like domain RRS1 PF04939.12 CRK31956.1 - 6.5e-42 143.2 8.1 7.2e-42 143.0 8.1 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) dCMP_cyt_deam_1 PF00383.23 CRK31957.1 - 6.2e-25 87.0 0.9 7.7e-25 86.7 0.9 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CRK31957.1 - 3.7e-10 39.7 0.0 5.1e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 MafB19-like deaminase ATP-synt_ab PF00006.25 CRK31959.1 - 1.1e-105 352.0 0.0 1.5e-105 351.5 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 CRK31959.1 - 1.3e-46 157.4 0.0 2.3e-46 156.6 0.0 1.5 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 CRK31959.1 - 4.6e-14 52.7 3.8 1e-13 51.6 3.8 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain LPD23 PF18838.1 CRK31959.1 - 0.092 12.5 0.1 0.2 11.4 0.1 1.5 1 0 0 1 1 1 0 Large polyvalent protein associated domain 23 DUF4048 PF13257.6 CRK31960.1 - 2.1e-14 54.0 2.6 2.1e-14 54.0 2.6 3.0 2 1 1 3 3 3 1 Domain of unknown function (DUF4048) DNA_ligase_A_N PF04675.14 CRK31961.1 - 3.7e-22 79.5 0.0 8.4e-22 78.3 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_M PF01068.21 CRK31961.1 - 4e-13 49.5 0.1 2.6e-08 33.7 0.0 2.5 1 1 1 2 2 2 2 ATP dependent DNA ligase domain RNA_ligase PF09414.10 CRK31961.1 - 0.00027 21.3 0.0 0.051 13.9 0.0 2.5 1 1 1 2 2 2 2 RNA ligase GBP PF02263.19 CRK31961.1 - 0.1 11.9 0.6 2.1 7.5 0.1 2.2 2 0 0 2 2 2 0 Guanylate-binding protein, N-terminal domain DIOX_N PF14226.6 CRK31962.1 - 1.9e-22 80.3 0.0 3.3e-22 79.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 CRK31962.1 - 4.5e-13 49.6 0.0 8.7e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MKT1_N PF12247.8 CRK31963.1 - 2.9e-27 94.9 0.1 6.2e-27 93.8 0.1 1.6 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.17 CRK31963.1 - 0.00075 19.9 0.0 0.0019 18.7 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain DNMT1-RFD PF12047.8 CRK31964.1 - 0.00018 21.6 0.0 0.00043 20.3 0.0 1.6 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain AsnC_trans_reg2 PF17805.1 CRK31964.1 - 0.023 14.9 0.2 0.063 13.4 0.2 1.7 1 0 0 1 1 1 0 AsnC-like ligand binding domain Cwf_Cwc_15 PF04889.12 CRK31964.1 - 1.1 8.9 10.8 0.3 10.8 1.7 2.5 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein ERG2_Sigma1R PF04622.12 CRK31966.1 - 3.7e-93 310.7 0.3 4.3e-93 310.4 0.3 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein EXOSC1 PF10447.9 CRK31967.1 - 1.1e-18 67.8 2.3 1.2e-13 51.7 0.1 2.5 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 CRK31967.1 - 5.5e-09 35.7 0.6 1.2e-08 34.6 0.6 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region Pox_A32 PF04665.12 CRK31967.1 - 0.19 11.2 0.0 0.25 10.8 0.0 1.1 1 0 0 1 1 1 0 Poxvirus A32 protein Sec2p PF06428.11 CRK31968.1 - 2.6e-11 43.3 6.0 2.6e-11 43.3 6.0 2.3 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p Jnk-SapK_ap_N PF09744.9 CRK31968.1 - 0.075 13.3 17.2 0.4 10.9 9.6 2.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Atg14 PF10186.9 CRK31968.1 - 0.076 12.1 7.8 1.6 7.8 0.1 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4795 PF16043.5 CRK31968.1 - 0.077 12.6 3.3 1.6 8.3 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) CCDC53 PF10152.9 CRK31968.1 - 0.21 12.0 8.5 2.3 8.6 8.5 2.5 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex Exonuc_VII_L PF02601.15 CRK31968.1 - 0.23 11.0 10.7 0.2 11.2 4.8 2.0 2 0 0 2 2 2 0 Exonuclease VII, large subunit SlyX PF04102.12 CRK31968.1 - 0.32 11.7 21.1 0.64 10.7 1.9 3.9 2 2 1 3 3 3 0 SlyX DivIC PF04977.15 CRK31968.1 - 0.49 10.2 9.2 0.67 9.8 1.8 2.8 2 1 0 2 2 2 0 Septum formation initiator Fez1 PF06818.15 CRK31968.1 - 0.52 10.7 10.0 76 3.7 10.0 2.2 1 1 0 1 1 1 0 Fez1 HAUS-augmin3 PF14932.6 CRK31968.1 - 0.74 9.3 10.9 0.21 11.1 3.6 2.3 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 DUF16 PF01519.16 CRK31968.1 - 0.78 10.3 3.0 14 6.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF16 Mod_r PF07200.13 CRK31968.1 - 1.3 9.1 10.0 0.6 10.2 0.9 2.2 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Phage_GPO PF05929.11 CRK31968.1 - 3.3 7.3 7.4 3 7.4 0.9 2.1 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase HR1 PF02185.16 CRK31968.1 - 4.1 7.6 13.5 3.1 8.0 0.7 3.2 3 1 0 3 3 3 0 Hr1 repeat MbeD_MobD PF04899.12 CRK31968.1 - 7 6.9 11.3 2.1 8.5 3.5 3.1 2 2 0 2 2 2 0 MbeD/MobD like HET PF06985.11 CRK31969.1 - 3.2e-37 128.1 3.5 4.5e-37 127.6 3.5 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF5134 PF17197.4 CRK31969.1 - 0.082 12.8 0.7 0.13 12.1 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5134) NmrA PF05368.13 CRK31970.1 - 7.3e-80 267.9 0.0 9.1e-80 267.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 CRK31970.1 - 7e-07 29.3 0.1 2.5e-05 24.3 0.1 2.2 1 1 0 1 1 1 1 NAD(P)H-binding Fungal_trans PF04082.18 CRK31972.1 - 2e-15 56.5 0.8 4.1e-15 55.5 0.8 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK31972.1 - 5.2e-06 26.5 11.8 8.7e-06 25.8 11.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC_tran PF00005.27 CRK31974.1 - 3.6e-28 98.8 0.0 9.5e-28 97.4 0.0 1.7 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 CRK31974.1 - 0.00084 18.8 0.0 0.88 9.0 0.0 2.1 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 CRK31974.1 - 0.0037 17.3 0.2 0.0078 16.3 0.2 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 CRK31974.1 - 0.0087 16.5 0.1 0.017 15.6 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain DUF87 PF01935.17 CRK31974.1 - 0.016 15.3 0.8 0.026 14.6 0.8 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain MeaB PF03308.16 CRK31974.1 - 0.032 13.2 0.2 0.052 12.5 0.2 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_21 PF13304.6 CRK31974.1 - 0.078 12.8 0.1 0.15 11.8 0.0 1.5 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 CRK31974.1 - 0.1 12.3 0.6 0.38 10.4 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.7 CRK31974.1 - 0.14 11.1 0.2 0.21 10.5 0.2 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_7 PF12775.7 CRK31974.1 - 0.2 11.1 0.1 0.34 10.4 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_29 PF13555.6 CRK31974.1 - 0.22 11.3 0.3 0.45 10.3 0.3 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 CRK31976.1 - 1.2e-15 58.2 0.0 1.7e-15 57.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CRK31976.1 - 0.071 12.5 0.0 0.082 12.3 0.0 1.1 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain ABC_membrane PF00664.23 CRK31977.1 - 1.7e-34 119.7 17.8 2.4e-34 119.2 17.8 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 CRK31977.1 - 2.8e-18 66.8 0.0 7.4e-18 65.4 0.0 1.8 2 0 0 2 2 2 1 ABC transporter Zeta_toxin PF06414.12 CRK31977.1 - 0.00067 19.0 0.0 0.0015 17.8 0.0 1.6 2 0 0 2 2 2 1 Zeta toxin AAA_29 PF13555.6 CRK31977.1 - 0.011 15.4 0.1 0.029 14.1 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Dynamin_N PF00350.23 CRK31977.1 - 0.018 15.1 0.4 0.038 14.0 0.4 1.5 1 0 0 1 1 1 0 Dynamin family AAA_16 PF13191.6 CRK31977.1 - 0.033 14.6 0.0 0.075 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 CRK31977.1 - 0.055 13.5 0.2 0.12 12.5 0.2 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CRK31977.1 - 0.058 13.3 0.2 0.12 12.3 0.2 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_28 PF13521.6 CRK31977.1 - 0.066 13.5 0.0 0.18 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 CRK31977.1 - 0.099 12.4 0.5 0.98 9.2 0.6 2.1 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system ABC_membrane PF00664.23 CRK31978.1 - 4.3e-56 190.6 37.9 8.2e-34 117.5 17.6 3.1 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 CRK31978.1 - 1.8e-18 67.4 0.0 4.7e-18 66.0 0.0 1.8 1 0 0 1 1 1 1 ABC transporter Zeta_toxin PF06414.12 CRK31978.1 - 0.0017 17.7 0.0 0.0032 16.8 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_29 PF13555.6 CRK31978.1 - 0.0088 15.8 0.1 0.026 14.3 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CRK31978.1 - 0.063 13.2 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 CRK31978.1 - 0.078 13.4 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 CRK31978.1 - 0.13 12.5 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 CRK31978.1 - 0.16 12.1 1.2 0.26 11.4 0.2 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase Dynamin_N PF00350.23 CRK31978.1 - 0.23 11.5 3.9 0.079 13.0 0.5 2.1 2 0 0 2 2 2 0 Dynamin family ABC_membrane PF00664.23 CRK31979.1 - 5.8e-23 81.9 12.4 5.9e-20 72.0 6.9 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region DEAD PF00270.29 CRK31982.1 - 3.9e-09 36.5 0.0 6.4e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Proteasome PF00227.26 CRK31983.1 - 3.6e-37 127.7 0.0 4.1e-37 127.5 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit DUF3383 PF11863.8 CRK31983.1 - 0.031 13.3 0.0 0.036 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3383) GluRS_N PF18466.1 CRK31983.1 - 0.27 11.7 2.9 0.21 12.0 1.2 1.7 2 0 0 2 2 2 0 Glutamate--tRNA ligase N-terminal domain WD40 PF00400.32 CRK31984.1 - 1.6e-24 85.6 16.2 1.2e-05 25.9 0.0 7.8 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK31984.1 - 0.00052 20.3 0.0 0.44 10.9 0.0 3.7 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain GTP-bdg_M PF16360.5 CRK31984.1 - 0.00055 20.5 1.4 1.4 9.5 0.1 2.6 2 0 0 2 2 2 2 GTP-binding GTPase Middle Region Peptidase_M4 PF01447.18 CRK31984.1 - 0.0041 17.6 2.9 2.5 8.6 0.3 2.5 2 0 0 2 2 2 2 Thermolysin metallopeptidase, catalytic domain MAGSP PF03082.14 CRK31984.1 - 0.018 14.6 0.1 4.9 6.7 0.0 2.3 2 0 0 2 2 2 0 Male accessory gland secretory protein WD40_like PF17005.5 CRK31984.1 - 0.037 13.3 0.0 0.12 11.7 0.0 1.9 3 0 0 3 3 3 0 WD40-like domain Nup160 PF11715.8 CRK31984.1 - 0.038 12.6 0.0 0.86 8.2 0.1 2.8 3 1 0 3 3 3 0 Nucleoporin Nup120/160 Caskin-Pro-rich PF16907.5 CRK31984.1 - 0.056 14.0 9.5 1.5 9.4 1.3 3.1 2 0 0 2 2 2 0 Proline rich region of Caskin proteins YpsA PF06908.11 CRK31984.1 - 1.7 8.6 3.8 29 4.6 0.3 2.3 2 0 0 2 2 2 0 YspA SLOG family PRP4 PF08799.11 CRK31984.1 - 2.8 7.6 6.9 17 5.1 0.7 2.6 2 0 0 2 2 2 0 pre-mRNA processing factor 4 (PRP4) like Peptidase_C48 PF02902.19 CRK31985.1 - 4.6e-36 124.7 0.0 8.2e-36 123.9 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DNApol3-delta_C PF09115.10 CRK31985.1 - 0.03 14.8 0.1 0.069 13.7 0.1 1.6 1 0 0 1 1 1 0 DNA polymerase III, delta subunit, C terminal Pmp3 PF01679.17 CRK31987.1 - 8e-15 54.8 9.6 1e-14 54.4 9.6 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF872 PF05915.12 CRK31987.1 - 0.13 12.4 4.3 0.19 11.9 4.3 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) RseC_MucC PF04246.12 CRK31987.1 - 0.27 11.2 1.4 0.33 10.9 1.4 1.1 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC zf-RanBP PF00641.18 CRK31989.1 - 2.2e-18 65.3 13.3 8e-11 41.1 1.6 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RNase_T PF00929.24 CRK31989.1 - 2.4e-05 24.9 0.0 3.6e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Exonuclease CAF1C_H4-bd PF12265.8 CRK31990.1 - 2.4e-26 91.8 0.1 1e-25 89.8 0.1 2.2 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 CRK31990.1 - 1.4e-18 66.9 8.3 7.8e-06 26.5 0.2 6.2 6 1 0 6 6 6 4 WD domain, G-beta repeat XRN_M PF17846.1 CRK31991.1 - 3e-103 346.1 4.1 5e-103 345.4 4.1 1.3 1 0 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 CRK31991.1 - 1.7e-97 325.6 0.2 3.2e-97 324.7 0.0 1.6 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus XRN1_D1 PF18332.1 CRK31991.1 - 1.6e-73 246.6 0.1 3.1e-73 245.7 0.1 1.5 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain XRN1_D2_D3 PF18334.1 CRK31991.1 - 2.7e-32 110.8 0.0 1e-31 109.0 0.0 2.1 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D2/D3 domain SH3_12 PF18129.1 CRK31991.1 - 2.7e-21 75.4 0.3 6e-21 74.3 0.2 1.7 2 0 0 2 2 2 1 Xrn1 SH3-like domain Xrn1_D3 PF18194.1 CRK31991.1 - 6.8e-05 22.9 0.1 0.00016 21.7 0.1 1.6 1 0 0 1 1 1 1 Exoribonuclease 1 Domain-3 Thioredoxin_11 PF18078.1 CRK31991.1 - 1.7 8.8 10.0 0.91 9.7 0.9 3.0 3 0 0 3 3 3 0 Thioredoxin-like SNTX domain Pkinase PF00069.25 CRK31993.1 - 9.1e-69 231.7 0.0 1.2e-68 231.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK31993.1 - 1.5e-35 122.8 0.0 2.9e-35 121.8 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CRK31993.1 - 0.011 14.7 0.1 0.032 13.2 0.0 1.6 2 0 0 2 2 2 0 Haspin like kinase domain Kinase-like PF14531.6 CRK31993.1 - 0.027 13.8 0.0 0.043 13.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Glycogen_syn PF05693.13 CRK31994.1 - 7.1e-237 788.0 1.8 3.2e-175 584.3 0.3 2.0 1 1 1 2 2 2 2 Glycogen synthase Glyco_transf_4 PF13439.6 CRK31994.1 - 6.2e-06 26.3 0.3 1.5e-05 25.1 0.1 1.8 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_transf_5 PF08323.11 CRK31994.1 - 8.1e-06 25.7 0.1 1.4e-05 24.9 0.1 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_4_4 PF13579.6 CRK31994.1 - 0.0011 19.5 0.0 0.0019 18.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain HlyD_2 PF12700.7 CRK31994.1 - 0.24 10.1 0.0 0.35 9.5 0.0 1.2 1 0 0 1 1 1 0 HlyD family secretion protein F-box-like PF12937.7 CRK31995.1 - 8.9e-09 35.1 0.4 2.2e-08 33.9 0.4 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CRK31995.1 - 5.8 6.9 10.2 0.51 10.3 0.6 3.1 4 0 0 4 4 4 0 F-box domain Pcc1 PF09341.10 CRK31996.1 - 1.1e-29 102.4 1.5 1.8e-29 101.7 1.5 1.4 1 0 0 1 1 1 1 Transcription factor Pcc1 DSPn PF14671.6 CRK31997.1 - 3e-41 141.2 0.0 8.2e-39 133.3 0.0 2.6 2 1 0 2 2 2 2 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 CRK31997.1 - 2.2e-16 59.9 0.0 4.1e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CRK31997.1 - 4.9e-06 26.3 0.0 9.9e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 CRK31997.1 - 0.19 11.3 0.0 0.36 10.4 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family 7tm_2 PF00002.24 CRK31999.1 - 1.3e-07 31.2 14.2 1.3e-07 31.2 14.2 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) 7tm_2 PF00002.24 CRK32000.1 - 1.9e-07 30.6 14.8 1.9e-07 30.6 14.8 1.5 1 1 1 2 2 2 1 7 transmembrane receptor (Secretin family) Cellulase PF00150.18 CRK32001.1 - 7e-06 25.7 0.0 7.9e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase PF00150.18 CRK32002.1 - 3.8e-34 118.4 0.0 4.6e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CRT10 PF08728.10 CRK32003.1 - 1.4e-13 49.9 0.0 1.8e-11 43.0 0.0 2.2 2 0 0 2 2 2 2 CRT10 RXT2_N PF08595.11 CRK32003.1 - 0.047 13.7 1.0 0.088 12.8 0.5 1.7 2 0 0 2 2 2 0 RXT2-like, N-terminal NOA36 PF06524.12 CRK32003.1 - 1.3 8.3 10.2 2 7.6 10.2 1.2 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 CRK32003.1 - 3.1 8.2 17.6 7.8 7.0 17.6 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Ammonium_transp PF00909.21 CRK32004.1 - 3.4e-226 750.4 63.2 3.4e-113 378.4 27.6 2.0 2 0 0 2 2 2 2 Ammonium Transporter Family NAD_binding_8 PF13450.6 CRK32004.1 - 0.034 14.4 0.0 30 5.0 0.0 3.5 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Colicin PF01024.19 CRK32004.1 - 0.037 13.9 2.9 5.3 6.9 0.2 2.4 2 0 0 2 2 2 0 Colicin pore forming domain PspC PF04024.12 CRK32004.1 - 0.075 12.9 0.8 30 4.5 0.1 3.6 2 0 0 2 2 2 0 PspC domain His_Phos_2 PF00328.22 CRK32006.1 - 3.3e-49 168.2 0.0 4.1e-49 167.9 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) MSA-2c PF12238.8 CRK32006.1 - 1.2 9.1 3.1 1.9 8.5 3.1 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c TauD PF02668.16 CRK32007.1 - 6.4e-50 170.4 3.6 3.7e-24 86.0 0.3 2.4 2 0 0 2 2 2 2 Taurine catabolism dioxygenase TauD, TfdA family His_Phos_2 PF00328.22 CRK32007.1 - 2.3e-47 162.2 0.0 4.3e-47 161.3 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) CsiD PF08943.10 CRK32007.1 - 0.00072 18.7 1.2 0.89 8.6 0.1 2.3 2 0 0 2 2 2 2 CsiD Lsr2 PF11774.8 CRK32007.1 - 0.006 16.7 0.1 1.1 9.4 0.0 3.0 2 0 0 2 2 2 1 Lsr2 Ribosomal_L11_N PF03946.14 CRK32007.1 - 0.089 12.6 0.0 24 4.9 0.0 2.5 2 0 0 2 2 2 0 Ribosomal protein L11, N-terminal domain DUF3553 PF12073.8 CRK32007.1 - 0.16 11.7 0.1 27 4.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3553) PknH_C PF14032.6 CRK32007.1 - 0.47 10.3 1.8 22 4.8 0.3 2.4 2 0 0 2 2 2 0 PknH-like extracellular domain Birna_VP5 PF03042.14 CRK32007.1 - 0.55 10.3 3.6 16 5.5 0.6 2.6 2 0 0 2 2 2 0 Birnavirus VP5 protein Zn_clus PF00172.18 CRK32007.1 - 5.5 7.2 16.8 0.64 10.2 9.4 2.4 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase_Tyr PF07714.17 CRK32010.1 - 1.3e-05 24.7 0.1 0.013 14.8 0.0 2.8 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 CRK32010.1 - 0.00028 20.4 0.0 0.0018 17.7 0.0 2.3 3 0 0 3 3 3 1 Protein kinase domain Sulfate_transp PF00916.20 CRK32011.1 - 2.2e-36 125.5 9.3 3e-36 125.0 9.3 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 CRK32011.1 - 4.6e-08 32.7 0.0 1.2e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 STAS domain SWIM PF04434.17 CRK32011.1 - 0.0012 18.5 0.1 0.003 17.2 0.1 1.6 1 0 0 1 1 1 1 SWIM zinc finger STAS_2 PF13466.6 CRK32011.1 - 0.15 12.4 0.8 0.68 10.3 0.1 2.4 2 0 0 2 2 2 0 STAS domain Peptidase_S58 PF03576.14 CRK32012.1 - 0.024 14.2 0.2 0.031 13.8 0.2 1.1 1 0 0 1 1 1 0 Peptidase family S58 RabGAP-TBC PF00566.18 CRK32013.1 - 1.7e-08 34.4 0.0 2.5e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain HlyIII PF03006.20 CRK32014.1 - 8.5e-61 205.5 19.2 1e-60 205.3 19.2 1.1 1 0 0 1 1 1 1 Haemolysin-III related Planc_extracel PF07595.12 CRK32014.1 - 1.5 8.8 5.2 0.2 11.5 0.3 2.1 2 0 0 2 2 2 0 Planctomycete extracellular Ycf66_N PF07444.11 CRK32014.1 - 2.1 8.6 7.5 0.29 11.3 1.8 2.7 3 2 0 3 3 3 0 Ycf66 protein N-terminus DUF4131 PF13567.6 CRK32014.1 - 7.2 6.2 8.8 1.4 8.5 2.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Glyco_trans_2_3 PF13632.6 CRK32015.1 - 8.1e-20 71.6 0.3 1.7e-19 70.6 0.3 1.5 1 0 0 1 1 1 1 Glycosyl transferase family group 2 FKBP_C PF00254.28 CRK32017.1 - 1.5e-31 108.5 0.0 4.7e-31 107.0 0.0 1.9 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 CRK32017.1 - 4.8e-24 84.9 0.1 4.8e-24 84.9 0.1 2.5 2 2 0 2 2 2 1 Nucleoplasmin-like domain Pkinase PF00069.25 CRK32021.1 - 6.8e-48 163.3 0.3 5.1e-32 111.3 0.0 3.4 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CRK32021.1 - 5.7e-25 88.1 0.0 1.1e-17 64.1 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CRK32021.1 - 5.7e-08 33.0 15.0 0.00015 21.8 1.4 3.3 4 1 0 4 4 4 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CRK32021.1 - 7.3e-06 25.2 0.9 0.009 15.0 0.1 2.2 2 0 0 2 2 2 2 Haspin like kinase domain Kinase-like PF14531.6 CRK32021.1 - 6.2e-05 22.4 0.1 0.007 15.7 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pox_ser-thr_kin PF05445.11 CRK32021.1 - 0.0012 17.9 0.2 0.29 10.0 0.0 2.1 2 0 0 2 2 2 2 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.11 CRK32021.1 - 0.002 17.2 0.1 1.3 8.1 0.0 2.3 2 0 0 2 2 2 2 Seadornavirus VP7 DUF1668 PF07893.13 CRK32021.1 - 0.036 13.4 0.3 0.45 9.8 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1668) Kdo PF06293.14 CRK32021.1 - 0.12 11.7 1.5 0.52 9.6 0.1 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Exo_endo_phos PF03372.23 CRK32023.1 - 2.7e-11 43.5 0.2 3.6e-11 43.0 0.2 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.32 CRK32025.1 - 1.2e-10 41.8 8.7 2.1e-09 37.9 0.0 3.8 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK32025.1 - 0.0003 21.0 0.0 0.015 15.6 0.0 2.3 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain zf-UBR PF02207.20 CRK32027.1 - 2.9e-19 69.0 12.7 6.9e-19 67.8 12.7 1.7 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 CRK32027.1 - 0.00013 21.7 0.1 0.00035 20.3 0.1 1.6 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS Pap_E4 PF02711.14 CRK32027.1 - 0.37 11.8 1.5 1.2 10.2 1.5 1.9 1 0 0 1 1 1 0 E4 protein WD40 PF00400.32 CRK32031.1 - 5e-16 58.8 10.6 0.0017 19.1 0.2 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK32031.1 - 9.6e-08 32.2 0.0 0.023 15.0 0.0 4.5 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 CRK32031.1 - 0.00083 19.2 0.2 4.7 7.3 0.0 3.5 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat RRM_1 PF00076.22 CRK32033.1 - 6.5e-09 35.5 0.0 2e-08 33.9 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CRK32033.1 - 1.6e-06 27.7 0.0 2.3e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Autophagy_act_C PF03987.15 CRK32034.1 - 6.7e-14 52.2 0.4 1.3e-13 51.3 0.3 1.6 1 1 0 1 1 1 1 Autophagocytosis associated protein, active-site domain AA_permease PF00324.21 CRK32035.1 - 3.6e-142 474.3 31.5 5.8e-142 473.7 31.5 1.3 1 0 0 1 1 1 1 Amino acid permease Glyco_hydro_47 PF01532.20 CRK32035.1 - 2.3e-131 438.9 0.0 1.4e-65 222.0 0.1 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 47 AA_permease_2 PF13520.6 CRK32035.1 - 2.9e-38 131.8 32.1 4.1e-38 131.3 32.1 1.1 1 0 0 1 1 1 1 Amino acid permease SnoaL_2 PF12680.7 CRK32036.1 - 0.015 15.9 0.4 0.088 13.5 0.0 2.3 2 1 0 2 2 2 0 SnoaL-like domain DUF5383 PF17355.2 CRK32037.1 - 0.21 11.9 0.0 0.21 11.9 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5383) AA_permease_2 PF13520.6 CRK32038.1 - 0.0023 16.8 0.2 0.0028 16.5 0.2 1.0 1 0 0 1 1 1 1 Amino acid permease Yip1 PF04893.17 CRK32038.1 - 0.019 14.7 1.9 0.022 14.5 1.9 1.0 1 0 0 1 1 1 0 Yip1 domain SVM_signal PF12113.8 CRK32038.1 - 0.072 13.0 0.9 0.14 12.1 0.9 1.5 1 0 0 1 1 1 0 SVM protein signal sequence DUF4605 PF15378.6 CRK32038.1 - 1 9.3 6.5 1.4 8.9 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4605) Insulin_TMD PF17870.1 CRK32038.1 - 2.1 8.5 7.7 2.5 8.3 1.3 2.2 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment adh_short_C2 PF13561.6 CRK32039.1 - 9.8e-41 139.8 1.8 1.6e-40 139.1 1.8 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRK32039.1 - 7.7e-30 103.8 0.5 1.1e-29 103.2 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CRK32039.1 - 2.7e-07 30.7 0.7 8.3e-06 25.8 0.1 2.1 2 0 0 2 2 2 1 KR domain Lum_binding PF00677.17 CRK32040.1 - 6.5e-17 61.3 0.3 1.4e-16 60.2 0.3 1.5 1 0 0 1 1 1 1 Lumazine binding domain PGM_PMM_IV PF00408.20 CRK32040.1 - 1.3e-11 44.4 1.1 3.5e-11 43.1 0.5 2.1 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_I PF02878.16 CRK32040.1 - 5.2e-09 35.9 0.1 6.5e-07 29.1 0.0 3.1 2 1 1 3 3 3 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 CRK32040.1 - 0.00059 20.0 0.0 0.0015 18.7 0.0 1.7 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 CRK32040.1 - 0.026 15.1 0.4 0.26 11.9 0.2 2.8 2 1 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II DUF2953 PF11167.8 CRK32042.1 - 0.17 12.0 0.1 0.24 11.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2953) Pex14_N PF04695.13 CRK32043.1 - 2.7 8.6 9.2 0.28 11.8 4.4 1.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Zn_clus PF00172.18 CRK32044.1 - 5.4e-08 32.8 14.4 5.4e-08 32.8 14.4 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 CRK32044.1 - 3.3e-07 29.6 0.0 6.2e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DinB_2 PF12867.7 CRK32044.1 - 0.066 13.7 0.0 0.51 10.9 0.0 2.4 2 0 0 2 2 2 0 DinB superfamily MFS_1 PF07690.16 CRK32045.1 - 1.3e-31 109.9 31.7 1.3e-31 109.9 31.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK32045.1 - 1.4e-10 40.7 10.3 1.4e-10 40.7 10.3 3.2 3 1 1 4 4 4 1 Sugar (and other) transporter Ferric_reduct PF01794.19 CRK32046.1 - 2.6e-09 37.2 11.3 1.4e-08 34.9 0.9 3.1 2 1 1 3 3 3 2 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 CRK32046.1 - 1.4e-07 31.6 0.0 0.00051 20.1 0.0 3.2 3 0 0 3 3 3 2 FAD-binding domain NAD_binding_6 PF08030.12 CRK32046.1 - 2.5e-05 24.5 0.0 0.085 13.0 0.0 2.5 1 1 1 2 2 2 2 Ferric reductase NAD binding domain IMUP PF15761.5 CRK32046.1 - 0.69 10.6 15.9 0.053 14.2 7.1 2.3 2 0 0 2 2 2 0 Immortalisation up-regulated protein Peptidase_M14 PF00246.24 CRK32047.1 - 4.6e-69 233.4 0.0 5.5e-69 233.1 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Pec_lyase_C PF00544.19 CRK32049.1 - 6.4e-22 78.2 8.6 7.5e-21 74.7 8.6 2.1 1 1 0 1 1 1 1 Pectate lyase CBM_1 PF00734.18 CRK32049.1 - 3.3e-11 42.9 14.0 3.3e-11 42.9 14.0 2.8 3 0 0 3 3 3 1 Fungal cellulose binding domain Beta_helix PF13229.6 CRK32049.1 - 2.4e-07 30.7 16.2 2.9e-05 24.0 7.7 2.3 1 1 1 2 2 2 2 Right handed beta helix region Pectate_lyase_3 PF12708.7 CRK32049.1 - 0.043 13.6 8.2 0.028 14.3 4.5 2.1 1 1 1 2 2 2 0 Pectate lyase superfamily protein ApbA_C PF08546.11 CRK32050.1 - 1.8e-27 96.0 0.1 3.3e-27 95.1 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 CRK32050.1 - 1.7e-18 66.7 0.0 2.9e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ACBP PF00887.19 CRK32057.1 - 4.1e-24 84.6 0.0 6.6e-24 83.9 0.0 1.3 1 0 0 1 1 1 1 Acyl CoA binding protein TANGO2 PF05742.12 CRK32058.1 - 2.2e-43 149.1 0.0 2.5e-43 149.0 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 SprT-like PF10263.9 CRK32059.1 - 1.5e-11 44.1 0.1 4.5e-11 42.6 0.1 1.7 1 1 0 1 1 1 1 SprT-like family ATE_C PF04377.15 CRK32060.1 - 1.2e-33 116.6 0.1 2e-33 115.9 0.1 1.3 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 CRK32060.1 - 9.4e-21 74.0 0.1 1.7e-20 73.2 0.1 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus RNase_PH PF01138.21 CRK32060.1 - 3.9e-12 46.8 0.0 7.8e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CRK32060.1 - 0.011 15.8 0.0 0.027 14.5 0.0 1.7 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 Cytochrom_C PF00034.21 CRK32062.1 - 2.4e-12 47.8 0.1 3.1e-12 47.5 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 CRK32062.1 - 5e-09 36.4 2.6 1.5e-08 34.8 2.6 1.7 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 CRK32062.1 - 0.0062 16.2 0.5 0.054 13.2 0.1 2.2 2 1 0 2 2 2 1 Cytochrome c-550 domain AAA PF00004.29 CRK32063.1 - 6.9e-63 211.0 0.0 7.8e-45 152.5 0.0 2.9 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CRK32063.1 - 1.4e-12 47.2 0.2 8.5e-07 28.7 0.1 2.6 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 CRK32063.1 - 1.4e-10 41.9 0.4 0.00087 19.7 0.0 4.6 3 2 1 4 4 4 2 AAA ATPase domain AAA_5 PF07728.14 CRK32063.1 - 3.2e-06 27.2 0.1 0.009 16.0 0.0 3.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CRK32063.1 - 1.2e-05 25.6 0.1 0.012 15.9 0.0 4.0 2 2 1 3 3 3 1 AAA domain RuvB_N PF05496.12 CRK32063.1 - 1.4e-05 24.9 0.0 0.00045 20.0 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 CRK32063.1 - 5.3e-05 23.4 0.0 0.0091 16.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 CRK32063.1 - 0.00012 22.3 0.0 0.0012 18.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Rad17 PF03215.15 CRK32063.1 - 0.00012 22.0 0.0 0.15 12.0 0.0 2.5 2 1 0 2 2 2 2 Rad17 P-loop domain AAA_18 PF13238.6 CRK32063.1 - 0.00039 21.0 0.3 0.39 11.3 0.0 3.1 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.12 CRK32063.1 - 0.0004 19.7 0.5 0.048 12.9 0.0 2.9 3 0 0 3 3 3 1 Zeta toxin AAA_28 PF13521.6 CRK32063.1 - 0.0006 20.1 0.2 0.77 10.0 0.0 3.1 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 CRK32063.1 - 0.00074 19.9 0.0 0.053 13.9 0.0 2.6 2 0 0 2 2 2 1 RNA helicase Sigma54_activ_2 PF14532.6 CRK32063.1 - 0.0017 18.5 0.0 0.048 13.8 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 CRK32063.1 - 0.0025 17.3 0.2 0.08 12.3 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 CRK32063.1 - 0.0042 16.9 0.0 0.047 13.4 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_11 PF13086.6 CRK32063.1 - 0.005 16.7 3.2 2.9 7.6 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_14 PF13173.6 CRK32063.1 - 0.0064 16.5 0.0 0.08 13.0 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.6 CRK32063.1 - 0.0078 15.8 0.3 5.4 6.5 0.0 3.4 3 1 0 3 3 3 1 AAA domain Sigma54_activat PF00158.26 CRK32063.1 - 0.015 15.0 0.0 0.66 9.7 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_30 PF13604.6 CRK32063.1 - 0.036 13.8 0.1 7.9 6.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 CRK32063.1 - 0.04 13.1 0.0 0.48 9.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_17 PF13207.6 CRK32063.1 - 0.061 13.8 0.3 2.7 8.4 0.0 3.1 3 0 0 3 3 2 0 AAA domain ABC_tran PF00005.27 CRK32063.1 - 0.064 13.8 0.2 3.5 8.2 0.0 3.1 3 1 0 3 3 3 0 ABC transporter Viral_helicase1 PF01443.18 CRK32063.1 - 0.085 12.6 0.0 1.8 8.2 0.0 2.6 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase TIP49 PF06068.13 CRK32063.1 - 0.12 11.5 0.1 0.34 10.1 0.0 1.7 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_19 PF13245.6 CRK32063.1 - 0.13 12.6 0.1 8.7 6.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 CRK32063.1 - 0.13 12.1 0.0 2.6 7.9 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 CRK32063.1 - 0.14 11.6 0.0 1.1 8.7 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region Calpain_inhib PF00748.19 CRK32063.1 - 0.55 10.7 10.0 0.46 11.0 0.7 2.4 2 0 0 2 2 2 0 Calpain inhibitor Snf7 PF03357.21 CRK32064.1 - 1.7e-27 96.1 11.9 2.3e-27 95.7 11.9 1.2 1 0 0 1 1 1 1 Snf7 DUF2293 PF10056.9 CRK32065.1 - 3.9e-29 100.7 0.2 9.1e-29 99.5 0.2 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) KAR9 PF08580.10 CRK32065.1 - 0.012 14.2 1.3 0.019 13.5 1.3 1.3 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Mito_carr PF00153.27 CRK32066.1 - 5.8e-38 128.7 9.8 3.6e-14 52.4 0.2 4.6 4 1 0 4 4 4 3 Mitochondrial carrier protein RNA_pol_Rpb1_1 PF04997.12 CRK32067.1 - 5.7e-48 163.9 0.0 6.4e-48 163.7 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 CRK32067.1 - 6.6e-11 42.7 0.0 1.1e-10 42.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 Pribosyltran PF00156.27 CRK32068.1 - 4.3e-06 26.3 0.0 6e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Longin PF13774.6 CRK32069.1 - 2.8e-26 91.4 0.0 3.5e-26 91.1 0.0 1.1 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 CRK32069.1 - 1.4e-10 40.8 0.7 1.9e-10 40.4 0.7 1.2 1 0 0 1 1 1 1 Synaptobrevin DUF676 PF05057.14 CRK32072.1 - 3.4e-41 141.2 0.0 5e-27 94.8 0.0 3.1 3 0 0 3 3 3 3 Putative serine esterase (DUF676) IBR PF01485.21 CRK32072.1 - 2.9e-09 37.0 47.6 1.9e-05 24.8 15.5 3.4 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 CRK32072.1 - 0.0034 17.2 3.5 0.0034 17.2 3.5 3.6 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CRK32072.1 - 0.0098 16.2 5.9 0.0098 16.2 5.9 3.4 3 0 0 3 3 3 1 Ring finger domain Lipase_3 PF01764.25 CRK32072.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.13 CRK32072.1 - 0.19 11.4 0.0 0.33 10.7 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein zf-RING_UBOX PF13445.6 CRK32072.1 - 0.21 11.6 8.3 0.029 14.4 3.8 1.9 2 0 0 2 2 2 0 RING-type zinc-finger eIF3g PF12353.8 CRK32073.1 - 2.1e-42 144.5 5.4 5.7e-42 143.0 4.7 2.1 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 CRK32073.1 - 1.4e-15 56.9 0.1 2.6e-15 56.0 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_7 PF18586.1 CRK32073.1 - 0.089 13.1 0.2 0.24 11.8 0.2 1.7 1 0 0 1 1 1 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 PH PF00169.29 CRK32073.1 - 0.098 13.2 0.0 0.45 11.0 0.0 2.2 2 0 0 2 2 2 0 PH domain Pox_A_type_inc PF04508.12 CRK32074.1 - 0.00011 21.8 0.5 0.00028 20.6 0.5 1.7 1 0 0 1 1 1 1 Viral A-type inclusion protein repeat SlyX PF04102.12 CRK32074.1 - 0.2 12.3 5.9 9.1 7.0 0.1 2.6 2 0 0 2 2 2 0 SlyX GreA_GreB_N PF03449.15 CRK32074.1 - 1 9.5 4.6 0.26 11.5 0.2 2.0 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal Glucosamine_iso PF01182.20 CRK32075.1 - 1.8e-56 191.5 0.0 2e-56 191.4 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Ribosomal_S27e PF01667.17 CRK32076.1 - 1.3e-28 98.4 7.5 1.5e-28 98.3 7.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S27 TF_Zn_Ribbon PF08271.12 CRK32076.1 - 0.072 12.6 3.5 0.094 12.2 3.5 1.2 1 0 0 1 1 1 0 TFIIB zinc-binding DUF5601 PF18151.1 CRK32077.1 - 1.1e-05 25.6 0.0 1.9e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) VPS9 PF02204.18 CRK32077.1 - 0.0004 20.5 0.1 0.00089 19.4 0.1 1.5 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain DUF3433 PF11915.8 CRK32079.1 - 3.2e-20 72.4 3.7 3.6e-20 72.2 2.3 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3433) ACBP PF00887.19 CRK32080.1 - 5.1e-09 36.2 0.0 5.6e-09 36.1 0.0 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein PI3_PI4_kinase PF00454.27 CRK32083.1 - 2.7e-10 40.5 0.0 3.3e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 CRK32083.1 - 1.1e-09 38.0 0.2 2.3e-09 36.9 0.2 1.6 1 0 0 1 1 1 1 FATC domain SET PF00856.28 CRK32084.1 - 2.7e-15 57.2 0.1 1.6e-14 54.6 0.1 2.0 1 1 0 1 1 1 1 SET domain N-SET PF11764.8 CRK32084.1 - 4e-08 33.5 0.0 6.3e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component N SNF5 PF04855.12 CRK32084.1 - 0.1 12.4 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 SNF5 / SMARCB1 / INI1 Pkinase PF00069.25 CRK32085.1 - 2e-65 220.8 0.1 1.2e-64 218.3 0.1 2.1 1 1 0 1 1 1 1 Protein kinase domain Fungal_KA1 PF16797.5 CRK32085.1 - 7.5e-42 141.8 0.6 1.4e-41 140.9 0.6 1.5 1 0 0 1 1 1 1 Fungal kinase associated-1 domain Pkinase_Tyr PF07714.17 CRK32085.1 - 2.4e-35 122.1 0.2 9.6e-35 120.1 0.1 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CRK32085.1 - 6.4e-06 25.7 0.0 1.1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CRK32085.1 - 0.00028 20.3 0.2 0.0007 19.0 0.2 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CRK32085.1 - 0.0003 19.9 0.0 0.00049 19.2 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CRK32085.1 - 0.0014 18.6 0.1 0.025 14.5 0.0 2.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CRK32085.1 - 0.0026 17.4 0.5 0.0055 16.3 0.5 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 CRK32085.1 - 0.015 14.9 1.0 0.031 13.9 0.4 1.7 2 0 0 2 2 2 0 RIO1 family SMC_N PF02463.19 CRK32086.1 - 2.3e-27 95.9 0.2 3.5e-27 95.3 0.2 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CRK32086.1 - 1.2e-16 61.9 0.0 1.2e-16 61.9 0.0 5.1 2 2 1 3 3 1 1 AAA domain AAA_15 PF13175.6 CRK32086.1 - 8.8e-08 32.2 17.7 9.4e-05 22.3 0.0 3.7 2 2 1 3 3 3 2 AAA ATPase domain AAA_21 PF13304.6 CRK32086.1 - 1.8e-06 28.0 2.6 0.037 13.8 0.0 3.6 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system IFT46_B_C PF12317.8 CRK32086.1 - 0.0033 17.2 0.8 0.0033 17.2 0.8 3.4 4 1 0 4 4 4 1 Intraflagellar transport complex B protein 46 C terminal AAA_29 PF13555.6 CRK32086.1 - 0.0049 16.6 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DotD PF16816.5 CRK32086.1 - 0.042 13.8 0.0 0.37 10.8 0.0 2.7 1 0 0 1 1 1 0 DotD protein AAA PF00004.29 CRK32086.1 - 0.061 13.8 0.0 0.37 11.2 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MCD_N PF17408.2 CRK32086.1 - 0.065 13.4 0.5 1.1 9.5 0.5 3.3 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase N-terminal domain RsgA_GTPase PF03193.16 CRK32086.1 - 0.23 11.4 1.4 0.91 9.4 0.0 2.8 3 0 0 3 3 3 0 RsgA GTPase AAA_27 PF13514.6 CRK32086.1 - 0.24 11.0 0.0 0.24 11.0 0.0 5.2 6 1 0 6 6 6 0 AAA domain AAA_25 PF13481.6 CRK32086.1 - 0.83 9.2 0.0 0.83 9.2 0.0 4.3 5 1 1 6 6 6 0 AAA domain DASH_Hsk3 PF08227.11 CRK32087.1 - 1.5e-20 73.3 4.1 1.6e-20 73.1 3.3 1.5 2 0 0 2 2 2 1 DASH complex subunit Hsk3 like BBS2_C PF14782.6 CRK32087.1 - 0.024 13.4 0.0 0.03 13.1 0.0 1.0 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal Rpr2 PF04032.16 CRK32088.1 - 5.4e-24 84.3 0.6 7.6e-24 83.8 0.6 1.2 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain PriA_CRR PF18319.1 CRK32088.1 - 0.0056 16.6 1.9 0.13 12.3 0.3 2.6 2 0 0 2 2 2 1 PriA DNA helicase Cys-rich region (CRR) domain ATP-synt_ab_N PF02874.23 CRK32091.1 - 0.087 13.4 0.3 0.099 13.2 0.3 1.1 1 0 0 1 1 1 0 ATP synthase alpha/beta family, beta-barrel domain Aldedh PF00171.22 CRK32095.1 - 9.8e-37 126.5 0.1 1.1e-36 126.4 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DNA_primase_lrg PF04104.14 CRK32098.1 - 2e-06 27.4 0.0 3.1e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit ACT PF01842.25 CRK32106.1 - 1.4e-15 56.8 0.1 2.2e-15 56.1 0.1 1.4 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 CRK32106.1 - 1.1e-08 34.8 0.0 1.5e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 ACT domain DUF104 PF01954.16 CRK32110.1 - 0.12 12.8 0.0 0.23 11.9 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function DUF104 Sel1 PF08238.12 CRK32110.1 - 0.31 11.8 0.2 0.31 11.8 0.2 1.9 2 0 0 2 2 2 0 Sel1 repeat COesterase PF00135.28 CRK32115.1 - 1.4e-39 136.4 0.1 2e-39 135.9 0.1 1.1 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S8 PF00082.22 CRK32115.1 - 1.3e-25 90.3 0.4 1.9e-25 89.8 0.4 1.3 1 0 0 1 1 1 1 Subtilase family PA PF02225.22 CRK32115.1 - 6.8e-06 26.0 0.1 0.00019 21.4 0.0 2.6 2 0 0 2 2 2 1 PA domain Abhydrolase_3 PF07859.13 CRK32115.1 - 2.4e-05 24.3 0.1 9.7e-05 22.3 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 CRK32117.1 - 6.2e-09 35.3 0.0 7.9e-09 34.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Cyclin PF08613.11 CRK32119.1 - 4.9e-43 147.3 0.0 8.8e-43 146.5 0.0 1.4 1 0 0 1 1 1 1 Cyclin TPP_enzyme_N PF02776.18 CRK32119.1 - 7.6e-39 133.1 0.0 1.8e-37 128.6 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 CRK32119.1 - 9.3e-23 80.7 0.1 1.7e-22 79.9 0.1 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 CRK32119.1 - 1e-13 51.2 0.0 3.5e-13 49.5 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Paf67 PF10255.9 CRK32119.1 - 0.25 10.3 0.0 0.36 9.8 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase I-associated factor PAF67 zf-C3HC4_2 PF13923.6 CRK32121.1 - 0.0051 16.6 0.9 0.0051 16.6 0.9 2.5 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CRK32121.1 - 0.0078 16.5 1.8 0.0078 16.5 1.8 3.2 4 1 0 4 4 4 1 Ring finger domain zf-RING_5 PF14634.6 CRK32121.1 - 0.015 15.2 6.7 0.021 14.7 3.4 3.0 2 1 0 2 2 2 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 CRK32121.1 - 0.018 15.1 0.4 0.018 15.1 0.4 2.5 1 1 1 2 2 2 0 RING-type zinc-finger Pellino PF04710.14 CRK32121.1 - 0.031 12.9 0.2 0.048 12.3 0.2 1.2 1 0 0 1 1 1 0 Pellino zf-C3HC4_3 PF13920.6 CRK32121.1 - 0.037 13.9 1.0 0.037 13.9 1.0 3.8 4 1 1 5 5 5 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CRK32121.1 - 0.048 13.6 0.6 0.048 13.6 0.6 2.6 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CRK32121.1 - 4 7.8 8.4 0.16 12.3 1.0 2.6 3 0 0 3 3 3 0 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 CRK32121.1 - 5.9 6.8 12.3 6.3 6.7 8.0 3.2 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 CRK32123.1 - 1.8e-08 34.6 5.3 6e-07 29.7 1.4 2.8 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 CRK32123.1 - 6.2e-08 32.4 3.0 2.6e-06 27.2 0.8 2.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 CRK32123.1 - 8.1e-07 29.0 0.1 3.4e-06 27.0 0.0 2.1 1 1 0 1 1 1 1 RING-type zinc-finger BTB PF00651.31 CRK32123.1 - 9.3e-06 25.8 0.0 9e-05 22.7 0.0 2.4 2 1 0 2 2 2 1 BTB/POZ domain zf-C3HC4_2 PF13923.6 CRK32123.1 - 2.7e-05 23.9 3.3 4.8e-05 23.1 0.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CRK32123.1 - 3.5e-05 23.6 0.7 0.0002 21.2 0.7 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CRK32123.1 - 0.00035 20.5 3.8 0.0034 17.3 4.3 2.3 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CRK32123.1 - 0.00074 19.3 0.4 0.00074 19.3 0.4 2.9 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 CRK32123.1 - 0.0042 16.8 1.0 0.058 13.2 0.1 2.6 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 CRK32123.1 - 0.0063 16.8 5.8 0.0079 16.5 0.9 2.5 2 0 0 2 2 2 1 RING-H2 zinc finger domain DUF4796 PF16044.5 CRK32123.1 - 0.041 13.5 1.1 0.1 12.2 0.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4796) zf-RING_11 PF17123.5 CRK32123.1 - 0.041 13.6 2.0 0.4 10.5 0.3 2.5 2 0 0 2 2 2 0 RING-like zinc finger zf-C3HC4_4 PF15227.6 CRK32123.1 - 0.4 10.9 6.1 0.1 12.8 0.7 2.5 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 CRK32123.1 - 0.78 9.6 2.4 0.9 9.4 0.3 2.0 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit COesterase PF00135.28 CRK32125.1 - 1.8e-61 208.6 0.1 3.1e-61 207.8 0.1 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CRK32125.1 - 0.0058 16.5 0.1 0.016 15.0 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 CRK32125.1 - 0.048 13.3 0.3 1.2 8.7 0.1 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold PALP PF00291.25 CRK32129.1 - 4.6e-56 190.4 1.4 7.6e-56 189.7 1.1 1.4 1 1 1 2 2 2 1 Pyridoxal-phosphate dependent enzyme Aminotran_1_2 PF00155.21 CRK32131.1 - 1.6e-14 53.8 0.0 7.9e-14 51.6 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 CRK32131.1 - 0.004 16.0 0.0 0.016 14.0 0.0 1.9 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase Helicase_C PF00271.31 CRK32138.1 - 1.3e-10 41.6 0.0 5.7e-09 36.3 0.0 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain BpuJI_N PF11564.8 CRK32138.1 - 0.085 12.1 0.3 0.11 11.6 0.3 1.1 1 0 0 1 1 1 0 Restriction endonuclease BpuJI - N terminal EZH2_N PF18601.1 CRK32148.1 - 7.4e-11 42.2 0.4 1.4e-10 41.3 0.4 1.5 1 0 0 1 1 1 1 EZH2 N-terminal domain Ferric_reduct PF01794.19 CRK32152.1 - 1.6e-11 44.4 8.2 1.6e-11 44.4 8.2 1.6 2 0 0 2 2 2 1 Ferric reductase like transmembrane component DUF485 PF04341.12 CRK32152.1 - 2.6 8.0 7.5 5.6 7.0 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function, DUF485 Pkinase PF00069.25 CRK32156.1 - 1.8e-25 89.8 0.1 2.2e-25 89.6 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK32156.1 - 2.4e-09 36.9 0.1 2.8e-09 36.7 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CRK32164.1 - 7.2e-49 166.5 0.0 8.3e-49 166.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK32164.1 - 1e-21 77.4 0.0 1.1e-21 77.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CRK32164.1 - 2.1e-06 27.3 0.0 2.3e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Kinase-like YukC PF10140.9 CRK32164.1 - 0.0027 16.6 0.0 0.0038 16.1 0.0 1.1 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC Haspin_kinase PF12330.8 CRK32164.1 - 0.003 16.6 0.0 0.0034 16.4 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 CRK32164.1 - 0.013 15.1 0.1 0.016 14.8 0.1 1.1 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 CRK32164.1 - 0.022 14.7 0.1 0.03 14.2 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 CRK32164.1 - 0.034 13.5 0.1 0.055 12.8 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 CRK32164.1 - 0.12 11.3 0.1 0.16 10.9 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase POLO_box PF00659.18 CRK32168.1 - 1.8e-05 24.8 0.0 3e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 POLO box duplicated region Abi_C PF14355.6 CRK32168.1 - 0.12 12.5 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Abortive infection C-terminus M16C_assoc PF08367.11 CRK32176.1 - 2.6e-61 207.0 0.0 2.8e-61 206.8 0.0 1.0 1 0 0 1 1 1 1 Peptidase M16C associated HHH_8 PF14716.6 CRK32176.1 - 0.093 13.1 0.0 0.32 11.4 0.0 1.9 1 1 1 2 2 2 0 Helix-hairpin-helix domain PI-PLC-X PF00388.19 CRK32183.1 - 2.5e-27 95.2 0.0 3.5e-27 94.8 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain EF-hand_like PF09279.11 CRK32183.1 - 0.00041 20.8 0.0 0.00069 20.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like GDPD PF03009.17 CRK32183.1 - 0.19 11.4 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family Molybdopterin PF00384.22 CRK32187.1 - 1.9e-26 93.1 0.1 1.7e-17 63.5 0.0 2.0 1 1 1 2 2 2 2 Molybdopterin oxidoreductase TPP_enzyme_M PF00205.22 CRK32187.1 - 0.005 16.6 0.0 0.036 13.8 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Glyco_hydro_76 PF03663.14 CRK32195.1 - 1.3e-130 436.2 4.8 1.5e-130 436.0 4.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 WD40 PF00400.32 CRK32197.1 - 6.3e-20 71.1 25.7 5.3e-05 23.9 0.7 8.0 7 1 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK32197.1 - 4.2e-09 36.6 3.6 0.092 13.1 0.0 5.9 1 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CRK32197.1 - 2.1e-05 24.5 0.0 0.031 14.2 0.0 2.6 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A WD40_3 PF15911.5 CRK32197.1 - 0.017 15.1 0.0 0.079 13.0 0.0 2.2 1 0 0 1 1 1 0 WD domain, G-beta repeat PD40 PF07676.12 CRK32197.1 - 0.11 12.5 1.3 34 4.5 0.0 3.9 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat BBS1 PF14779.6 CRK32197.1 - 0.18 11.2 0.0 0.7 9.3 0.0 1.9 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 1 adh_short PF00106.25 CRK32200.1 - 3e-22 79.0 0.1 5.9e-20 71.6 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CRK32200.1 - 6.5e-14 52.1 0.1 7e-12 45.4 0.1 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK32200.1 - 1.2e-05 25.3 0.1 2e-05 24.6 0.1 1.4 1 0 0 1 1 1 1 KR domain DUF2057 PF09829.9 CRK32200.1 - 0.037 14.2 0.0 0.068 13.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) Amino_oxidase PF01593.24 CRK32202.1 - 5.9e-14 52.2 0.1 7.1e-14 51.9 0.1 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase CoA_transf_3 PF02515.17 CRK32204.1 - 6.2e-62 209.8 0.0 7.8e-62 209.5 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III Lactamase_B_2 PF12706.7 CRK32206.1 - 1.2e-15 57.6 0.2 1.8e-15 57.0 0.2 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 CRK32206.1 - 3.7e-15 56.2 0.0 5.2e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 CRK32206.1 - 0.032 14.2 0.4 1.6 8.7 0.0 2.7 3 0 0 3 3 3 0 Metallo-beta-lactamase superfamily MFS_1 PF07690.16 CRK32208.1 - 4.8e-25 88.2 76.3 1.1e-21 77.2 57.3 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily HMG_box PF00505.19 CRK32214.1 - 5.3e-05 23.5 0.0 9.4e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CRK32214.1 - 0.0047 17.5 0.1 0.0075 16.8 0.1 1.4 1 0 0 1 1 1 1 HMG-box domain TPPII_N PF12583.8 CRK32214.1 - 0.014 15.9 3.9 0.017 15.7 3.9 1.1 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal ASFV_J13L PF05568.11 CRK32214.1 - 0.045 13.5 2.4 0.049 13.4 2.4 1.2 1 0 0 1 1 1 0 African swine fever virus J13L protein DUF2213 PF09979.9 CRK32214.1 - 0.13 12.3 0.1 0.17 11.8 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2213) Glyco_hydro_2_N PF02837.18 CRK32217.1 - 5.4e-29 101.3 0.0 7.5e-29 100.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Sulfatase PF00884.23 CRK32231.1 - 8.7e-17 61.5 0.0 8.9e-17 61.4 0.0 1.0 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 CRK32231.1 - 0.048 13.2 0.0 0.064 12.8 0.0 1.1 1 0 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase Adeno_100 PF02438.16 CRK32231.1 - 0.11 10.7 0.0 0.14 10.3 0.0 1.2 1 0 0 1 1 1 0 Late 100kD protein CDC14 PF08045.11 CRK32232.1 - 6.8e-63 212.4 0.0 7.8e-63 212.2 0.0 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component Apt1 PF10351.9 CRK32234.1 - 4.8e-109 365.4 0.1 4.8e-109 365.4 0.1 2.1 2 1 0 2 2 2 1 Golgi-body localisation protein domain Fmp27 PF10344.9 CRK32234.1 - 1.9e-33 115.6 0.3 1.9e-33 115.6 0.3 1.5 2 0 0 2 2 2 1 Mitochondrial protein from FMP27 DUF5132 PF17195.4 CRK32235.1 - 0.11 12.6 0.1 0.23 11.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF5132) POPLD PF08170.12 CRK32237.1 - 0.21 12.0 1.0 0.35 11.2 1.0 1.4 1 1 0 1 1 1 0 POPLD (NUC188) domain DUF3405 PF11885.8 CRK32240.1 - 6.8e-48 163.5 2.7 9.1e-47 159.8 2.7 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3405) RasGAP PF00616.19 CRK32243.1 - 1e-33 116.8 0.0 1.5e-33 116.3 0.0 1.2 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase RRM_1 PF00076.22 CRK32244.1 - 0.024 14.5 0.0 0.047 13.5 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RsmJ PF04378.13 CRK32244.1 - 0.14 11.4 0.1 0.18 11.0 0.1 1.2 1 0 0 1 1 1 0 Ribosomal RNA large subunit methyltransferase D, RlmJ CDC45 PF02724.14 CRK32244.1 - 0.7 8.1 3.8 0.85 7.8 3.8 1.0 1 0 0 1 1 1 0 CDC45-like protein RPA43_OB PF17875.1 CRK32244.1 - 8.7 7.0 7.0 23 5.6 7.0 1.8 1 1 0 1 1 1 0 RPA43 OB domain in RNA Pol I Rad52_Rad22 PF04098.15 CRK32245.1 - 3.5e-06 27.0 0.0 6.2e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein APC1_C PF18122.1 CRK32245.1 - 0.021 14.7 0.0 0.024 14.6 0.0 1.1 1 0 0 1 1 1 0 Anaphase-promoting complex sub unit 1 C-terminal domain Asn_synthase PF00733.21 CRK32246.1 - 8.2e-17 61.9 0.1 9.5e-17 61.7 0.1 1.0 1 0 0 1 1 1 1 Asparagine synthase E1-E2_ATPase PF00122.20 CRK32248.1 - 5.7e-13 48.8 4.4 7.2e-13 48.4 4.4 1.1 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 CRK32248.1 - 0.0006 20.2 0.0 0.0011 19.4 0.0 1.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RseC_MucC PF04246.12 CRK32248.1 - 1.3 8.9 3.4 1.9 8.4 3.4 1.4 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC ABC_tran PF00005.27 CRK32256.1 - 8.5e-13 49.0 0.0 1.4e-12 48.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CRK32256.1 - 2.9e-05 23.6 0.2 5.7e-05 22.7 0.2 1.3 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 CRK32256.1 - 0.0019 17.1 0.1 0.002 17.0 0.1 1.1 1 0 0 1 1 1 1 Predicted ATPase of the ABC class SbcCD_C PF13558.6 CRK32256.1 - 0.011 15.9 0.4 0.18 12.0 0.4 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA PF00004.29 CRK32256.1 - 0.074 13.5 0.0 0.1 13.0 0.0 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TFIID-31kDa PF02291.15 CRK32263.1 - 9.6e-39 132.2 0.0 1.1e-38 132.0 0.0 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit AdoHcyase PF05221.17 CRK32269.1 - 1.5e-54 185.2 0.4 1.4e-32 113.1 0.3 2.1 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 CRK32269.1 - 1e-23 84.2 2.6 1.8e-23 83.4 2.6 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ELFV_dehydrog PF00208.21 CRK32269.1 - 0.057 13.1 0.2 0.1 12.3 0.2 1.5 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 2-Hacid_dh_C PF02826.19 CRK32269.1 - 0.23 10.8 1.8 0.45 9.9 1.8 1.5 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADK_lid PF05191.14 CRK32273.1 - 8.8e-18 64.0 0.0 2.6e-17 62.5 0.0 1.8 2 0 0 2 2 2 1 Adenylate kinase, active site lid ADK PF00406.22 CRK32273.1 - 2.6e-12 47.1 0.0 3.2e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase HSP70 PF00012.20 CRK32275.1 - 6.2e-127 424.3 1.0 6.9e-127 424.1 1.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CRK32275.1 - 2.3e-16 59.5 0.1 3e-16 59.1 0.1 1.1 1 0 0 1 1 1 1 MreB/Mbl protein FGGY_C PF02782.16 CRK32275.1 - 0.00028 20.7 0.0 0.00054 19.8 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Actin PF00022.19 CRK32275.1 - 0.022 13.4 0.1 0.12 10.9 0.0 1.8 1 1 1 2 2 2 0 Actin DDR PF08841.10 CRK32275.1 - 0.032 13.2 0.1 0.39 9.6 0.1 2.1 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain DUF1464 PF07318.12 CRK32275.1 - 0.063 12.4 0.0 0.097 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1464) Acetyltransf_14 PF03421.16 CRK32275.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 YopJ Serine/Threonine acetyltransferase Med26 PF08711.11 CRK32279.1 - 2e-08 34.1 0.0 3.4e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Axin_b-cat_bind PF08833.10 CRK32280.1 - 0.15 12.2 0.5 0.34 11.1 0.1 1.7 2 0 0 2 2 2 0 Axin beta-catenin binding domain DUF4363 PF14276.6 CRK32282.1 - 0.24 11.5 0.0 0.35 11.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) MARVEL PF01284.23 CRK32283.1 - 5.4e-05 23.3 17.0 7.5e-05 22.8 17.0 1.2 1 0 0 1 1 1 1 Membrane-associating domain Neur_chan_memb PF02932.16 CRK32283.1 - 0.0066 16.5 2.1 0.014 15.5 0.0 2.1 2 1 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region DUF4293 PF14126.6 CRK32283.1 - 0.035 14.4 8.6 0.019 15.2 6.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) 7TMR-DISM_7TM PF07695.11 CRK32283.1 - 0.39 10.6 21.2 2.4 8.0 17.0 2.1 2 0 0 2 2 2 0 7TM diverse intracellular signalling SelK_SelG PF10961.8 CRK32283.1 - 0.4 11.3 0.0 0.4 11.3 0.0 2.3 2 0 0 2 2 2 0 Selenoprotein SelK_SelG DUF1003 PF06210.11 CRK32283.1 - 3 8.0 5.7 7 6.8 5.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) Diphthamide_syn PF01866.17 CRK32284.1 - 6.4e-82 275.4 0.0 8e-82 275.1 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein MFS_1 PF07690.16 CRK32285.1 - 1.8e-36 125.8 76.4 2.6e-29 102.3 42.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK32285.1 - 1.4e-11 43.9 33.5 3.4e-08 32.8 12.1 2.5 2 1 1 3 3 3 2 Sugar (and other) transporter Fungal_trans_2 PF11951.8 CRK32287.1 - 6e-13 48.4 0.0 4.3e-12 45.6 0.0 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Pyr_redox_2 PF07992.14 CRK32288.1 - 5.8e-52 176.7 2.6 8.5e-52 176.2 2.6 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 CRK32288.1 - 1.6e-15 56.8 0.0 3.5e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.27 CRK32288.1 - 1.2e-11 45.0 4.2 4.4e-11 43.2 0.5 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.6 CRK32288.1 - 2.1e-06 28.2 0.0 5.7e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Reductase C-terminal Rieske_2 PF13806.6 CRK32288.1 - 0.0001 22.2 0.0 0.00069 19.5 0.0 2.4 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain NAD_binding_9 PF13454.6 CRK32288.1 - 0.0015 18.5 4.1 0.081 12.9 0.0 3.2 3 0 0 3 3 3 2 FAD-NAD(P)-binding DUF1188 PF06690.11 CRK32288.1 - 0.076 12.6 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) NAD_binding_7 PF13241.6 CRK32288.1 - 0.12 12.9 0.4 4.3 7.8 0.0 2.5 1 1 1 2 2 2 0 Putative NAD(P)-binding Kelch_1 PF01344.25 CRK32288.1 - 1.6 8.4 5.3 4.7 6.9 0.6 3.0 3 0 0 3 3 3 0 Kelch motif PUL PF08324.11 CRK32289.1 - 3.2e-09 36.5 0.1 3.4e-09 36.3 0.1 1.0 1 0 0 1 1 1 1 PUL domain Kinesin PF00225.23 CRK32290.1 - 1.3e-67 228.1 0.0 1.5e-67 227.9 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CRK32290.1 - 8.8e-27 93.9 0.0 1.8e-26 92.9 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding DUF87 PF01935.17 CRK32290.1 - 0.13 12.4 1.3 0.32 11.0 0.0 2.1 3 0 0 3 3 3 0 Helicase HerA, central domain PYC_OADA PF02436.18 CRK32291.1 - 2.1e-70 236.5 0.0 2.5e-70 236.3 0.0 1.0 1 0 0 1 1 1 1 Conserved carboxylase domain DUF3572 PF12096.8 CRK32291.1 - 0.041 14.1 0.0 0.17 12.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3572) IF4E PF01652.18 CRK32292.1 - 5.2e-38 130.3 0.1 6.8e-38 130.0 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E UBA2_C PF16195.5 CRK32293.1 - 0.0042 17.8 1.0 0.0078 16.9 1.0 1.4 1 0 0 1 1 1 1 SUMO-activating enzyme subunit 2 C-terminus Kinesin PF00225.23 CRK32294.1 - 9.8e-115 383.0 0.0 1.5e-114 382.4 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CRK32294.1 - 3.9e-26 91.8 0.0 9.7e-26 90.5 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding Cytochrom_B562 PF07361.11 CRK32294.1 - 0.075 13.7 3.7 0.42 11.3 3.7 2.3 1 0 0 1 1 1 0 Cytochrome b562 YabA PF06156.13 CRK32294.1 - 0.57 10.8 6.4 18 6.1 0.0 3.6 2 1 1 3 3 3 0 Initiation control protein YabA DUF87 PF01935.17 CRK32294.1 - 0.78 9.8 0.0 0.78 9.8 0.0 3.3 3 1 0 3 3 3 0 Helicase HerA, central domain GDA1_CD39 PF01150.17 CRK32295.1 - 2e-13 49.8 0.0 2.5e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Peptidase_C97 PF05903.14 CRK32296.1 - 1.3e-34 119.2 0.0 2.3e-34 118.4 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUL PF08324.11 CRK32296.1 - 1.4e-29 103.2 0.1 2.3e-29 102.5 0.1 1.3 1 0 0 1 1 1 1 PUL domain Thioredoxin PF00085.20 CRK32296.1 - 7.8e-17 61.2 0.2 1.6e-16 60.2 0.2 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 CRK32296.1 - 0.00013 22.3 0.3 0.00046 20.6 0.3 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 CRK32296.1 - 0.00039 19.9 0.0 0.00071 19.0 0.0 1.4 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family TraF PF13728.6 CRK32296.1 - 0.015 15.2 0.1 0.03 14.2 0.1 1.5 1 0 0 1 1 1 0 F plasmid transfer operon protein GDA1_CD39 PF01150.17 CRK32297.1 - 2e-158 527.5 0.0 1.8e-99 333.3 0.0 2.0 1 1 1 2 2 2 2 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 CRK32297.1 - 0.0014 18.1 0.0 0.34 10.3 0.0 2.3 2 0 0 2 2 2 2 Ppx/GppA phosphatase family FeS PF04060.13 CRK32297.1 - 0.0091 15.6 4.4 2.3 7.9 0.4 2.9 2 0 0 2 2 2 2 Putative Fe-S cluster DUF4597 PF15366.6 CRK32297.1 - 0.039 13.7 0.0 14 5.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4597) AAA_lid_2 PF17863.1 CRK32298.1 - 1.3e-05 24.9 0.1 2.7e-05 23.9 0.1 1.5 1 0 0 1 1 1 1 AAA lid domain Inhibitor_Mig-6 PF11555.8 CRK32298.1 - 0.012 15.7 2.1 0.024 14.7 2.1 1.5 1 0 0 1 1 1 0 EGFR receptor inhibitor Mig-6 AAA_lid_2 PF17863.1 CRK32299.1 - 4.2e-05 23.3 0.1 8.9e-05 22.3 0.1 1.6 1 0 0 1 1 1 1 AAA lid domain PseudoU_synth_2 PF00849.22 CRK32299.1 - 0.11 12.6 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 RNA pseudouridylate synthase Ras PF00071.22 CRK32300.1 - 4e-57 192.3 0.1 4.7e-57 192.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CRK32300.1 - 4.6e-32 110.8 0.0 6.6e-32 110.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CRK32300.1 - 2.7e-13 49.7 0.0 3.2e-13 49.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CRK32300.1 - 5.2e-08 33.0 0.0 8.2e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CRK32300.1 - 2.8e-06 26.9 0.0 3.4e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CRK32300.1 - 4.9e-05 22.9 0.1 0.0015 18.1 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CRK32300.1 - 0.0001 22.3 0.1 0.0037 17.2 0.1 2.4 1 1 0 2 2 2 1 RsgA GTPase SRPRB PF09439.10 CRK32300.1 - 0.0024 17.3 0.0 0.003 17.0 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_5 PF07728.14 CRK32300.1 - 0.0036 17.3 0.0 0.0066 16.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) PduV-EutP PF10662.9 CRK32300.1 - 0.0068 16.1 0.1 0.13 12.0 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 CRK32300.1 - 0.0078 16.6 0.0 0.013 15.9 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CRK32300.1 - 0.0097 16.2 0.0 0.016 15.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.17 CRK32300.1 - 0.01 15.6 0.2 0.31 10.8 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 CRK32300.1 - 0.021 14.6 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 CRK32300.1 - 0.021 14.1 0.1 0.048 12.9 0.0 1.6 2 0 0 2 2 2 0 Septin AAA_7 PF12775.7 CRK32300.1 - 0.024 14.1 0.1 0.041 13.4 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region cobW PF02492.19 CRK32300.1 - 0.037 13.6 0.0 0.096 12.3 0.0 1.7 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 CRK32300.1 - 0.044 13.0 0.1 0.31 10.2 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain ATPase_2 PF01637.18 CRK32300.1 - 0.054 13.4 0.2 0.13 12.1 0.0 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 CRK32300.1 - 0.091 12.7 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 NTPase TniB PF05621.11 CRK32300.1 - 0.12 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein NACHT PF05729.12 CRK32300.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 CRK32300.1 - 0.15 12.5 0.0 0.52 10.7 0.0 1.9 2 0 0 2 2 2 0 RNA helicase AAA_21 PF13304.6 CRK32300.1 - 0.32 10.7 0.8 4.9 6.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system EamA PF00892.20 CRK32301.1 - 2.7e-13 50.3 31.9 3.4e-08 33.7 2.4 3.0 3 0 0 3 3 3 2 EamA-like transporter family DUF3955 PF13127.6 CRK32301.1 - 6.1e-09 35.6 0.2 6.1e-09 35.6 0.2 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF3955) SLC35F PF06027.12 CRK32301.1 - 3.4e-06 26.8 14.8 3.4e-06 26.8 14.8 1.5 2 0 0 2 2 2 1 Solute carrier family 35 UAA PF08449.11 CRK32301.1 - 0.00036 19.8 12.2 0.00068 18.9 12.2 1.4 1 0 0 1 1 1 1 UAA transporter family CRT-like PF08627.10 CRK32301.1 - 0.00046 19.3 4.0 0.048 12.6 0.0 2.2 2 0 0 2 2 2 2 CRT-like, chloroquine-resistance transporter-like Spore_YhaL PF14147.6 CRK32301.1 - 0.034 13.8 0.4 0.12 12.1 0.4 2.0 1 0 0 1 1 1 0 Sporulation protein YhaL Sacchrp_dh_C PF16653.5 CRK32302.1 - 1.4e-93 313.8 0.0 2.7e-93 312.9 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 CRK32302.1 - 5.1e-26 91.4 0.3 4.9e-24 85.0 0.1 2.5 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain WD40 PF00400.32 CRK32302.1 - 3.9e-13 49.6 5.8 0.0034 18.2 0.2 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK32302.1 - 2e-08 34.4 0.2 0.12 12.7 0.0 4.8 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Shikimate_DH PF01488.20 CRK32302.1 - 0.0027 17.8 0.0 0.0049 16.9 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 CRK32302.1 - 0.0039 17.1 0.0 0.0093 15.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)H-binding Spb1_C PF07780.12 CRK32303.1 - 2.6e-84 282.1 14.8 2.6e-84 282.1 14.8 3.9 4 0 0 4 4 4 1 Spb1 C-terminal domain FtsJ PF01728.19 CRK32303.1 - 1.3e-53 181.8 0.0 2.2e-53 181.0 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 CRK32303.1 - 6.6e-52 175.6 7.9 6.6e-52 175.6 7.9 4.8 5 1 0 5 5 5 2 Domain of unknown function (DUF3381) Strabismus PF06638.11 CRK32305.1 - 0.006 15.3 0.1 0.0067 15.1 0.1 1.0 1 0 0 1 1 1 1 Strabismus protein FMN_dh PF01070.18 CRK32306.1 - 2.2e-113 378.8 0.3 2.6e-113 378.6 0.3 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 CRK32306.1 - 0.00031 20.0 0.0 0.0007 18.8 0.1 1.5 2 0 0 2 2 2 1 Conserved region in glutamate synthase NMO PF03060.15 CRK32306.1 - 0.00067 19.1 0.2 0.0015 18.0 0.2 1.5 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 CRK32306.1 - 0.00097 18.2 0.4 0.0033 16.5 0.3 2.0 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Peptidase_S41 PF03572.18 CRK32307.1 - 0.012 15.2 0.2 0.024 14.2 0.1 1.6 1 1 0 1 1 1 0 Peptidase family S41 PARM PF17061.5 CRK32307.1 - 1.8 8.7 42.4 0.14 12.2 14.2 2.2 2 0 0 2 2 2 0 PARM 14-3-3 PF00244.20 CRK32308.1 - 2.1e-06 27.4 0.0 2e-05 24.2 0.0 2.0 2 0 0 2 2 2 1 14-3-3 protein Sterol-sensing PF12349.8 CRK32309.1 - 3.4e-39 134.1 7.7 6e-39 133.3 7.7 1.4 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 CRK32309.1 - 8.9e-13 47.2 4.5 1.2e-12 46.9 4.5 1.1 1 0 0 1 1 1 1 Patched family WD40 PF00400.32 CRK32309.1 - 0.064 14.2 1.7 0.15 12.9 0.3 2.6 2 0 0 2 2 2 0 WD domain, G-beta repeat Cupin_8 PF13621.6 CRK32310.1 - 9e-65 218.9 0.0 1.4e-64 218.3 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Epimerase PF01370.21 CRK32310.1 - 1.4e-13 50.8 0.1 4.6e-13 49.2 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CRK32310.1 - 3e-08 33.0 0.0 4.5e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Cupin_4 PF08007.12 CRK32310.1 - 2.5e-06 27.2 0.1 0.0013 18.2 0.1 2.4 2 0 0 2 2 2 2 Cupin superfamily protein NAD_binding_4 PF07993.12 CRK32310.1 - 4.7e-06 25.9 0.0 0.0017 17.6 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 CRK32310.1 - 5.4e-06 26.4 0.1 9.1e-06 25.7 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 CRK32310.1 - 2e-05 24.2 0.1 0.00016 21.2 0.1 2.2 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 CRK32310.1 - 2.9e-05 23.7 0.1 4.9e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family XPB_DRD PF18458.1 CRK32310.1 - 0.0024 17.7 0.3 0.0086 15.9 0.3 2.0 1 0 0 1 1 1 1 Xeroderma pigmentosum group B helicase damage recognition domain THUMP PF02926.17 CRK32310.1 - 0.018 15.1 0.0 0.054 13.6 0.0 1.7 1 1 0 1 1 1 0 THUMP domain adh_short PF00106.25 CRK32310.1 - 0.12 11.9 0.0 0.42 10.0 0.0 1.8 2 0 0 2 2 2 0 short chain dehydrogenase N-SET PF11764.8 CRK32311.1 - 7e-41 140.2 0.0 7e-41 140.2 0.0 2.0 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component N SET PF00856.28 CRK32311.1 - 8.7e-20 71.8 0.5 1e-18 68.3 0.1 2.7 2 1 0 2 2 2 1 SET domain Tropomyosin_1 PF12718.7 CRK32312.1 - 1.9e-53 180.4 32.3 2.4e-53 180.1 32.3 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 CRK32312.1 - 1.9e-08 34.0 32.6 0.00036 20.0 14.6 3.0 1 1 1 2 2 2 2 Tropomyosin DUF724 PF05266.14 CRK32312.1 - 0.00018 21.4 23.9 0.011 15.6 8.2 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF724) FlaC_arch PF05377.11 CRK32312.1 - 0.00059 20.2 21.7 0.25 11.8 0.5 4.4 3 2 1 4 4 4 3 Flagella accessory protein C (FlaC) ATG16 PF08614.11 CRK32312.1 - 0.0013 19.0 32.9 0.38 10.9 18.6 2.3 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) MAD PF05557.13 CRK32312.1 - 0.0014 17.1 10.9 0.0014 17.1 10.9 2.1 1 1 1 2 2 2 2 Mitotic checkpoint protein Spc7 PF08317.11 CRK32312.1 - 0.0015 17.5 32.6 0.01 14.7 13.6 2.0 1 1 1 2 2 2 2 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 CRK32312.1 - 0.0024 17.9 7.2 0.0024 17.9 7.2 2.8 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Taxilin PF09728.9 CRK32312.1 - 0.0037 16.5 30.2 0.088 12.0 8.2 2.1 1 1 1 2 2 2 2 Myosin-like coiled-coil protein BST2 PF16716.5 CRK32312.1 - 0.0048 17.5 4.3 0.0048 17.5 4.3 3.4 1 1 2 3 3 3 1 Bone marrow stromal antigen 2 ERM PF00769.19 CRK32312.1 - 0.0054 16.6 35.1 0.091 12.6 16.8 2.0 1 1 1 2 2 2 2 Ezrin/radixin/moesin family DUF3450 PF11932.8 CRK32312.1 - 0.007 15.7 25.6 0.32 10.3 8.8 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3450) Laminin_II PF06009.12 CRK32312.1 - 0.012 15.6 6.2 0.012 15.6 6.2 2.2 1 1 1 2 2 2 0 Laminin Domain II GAS PF13851.6 CRK32312.1 - 0.014 14.8 32.5 0.31 10.3 14.7 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Lebercilin PF15619.6 CRK32312.1 - 0.014 15.0 32.3 1.6e+02 1.8 32.4 2.2 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease DUF4200 PF13863.6 CRK32312.1 - 0.015 15.7 31.9 0.089 13.2 14.9 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) TMF_TATA_bd PF12325.8 CRK32312.1 - 0.016 15.4 26.9 0.13 12.5 15.1 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Cep57_CLD_2 PF14197.6 CRK32312.1 - 0.02 15.0 30.7 4.1 7.6 9.2 3.6 2 2 0 2 2 2 0 Centrosome localisation domain of PPC89 Alanine_zipper PF11839.8 CRK32312.1 - 0.02 15.2 7.4 1.6 9.2 0.6 3.6 2 1 0 3 3 2 0 Alanine-zipper, major outer membrane lipoprotein KLRAQ PF10205.9 CRK32312.1 - 0.023 14.9 8.4 0.023 14.9 8.4 3.1 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein Uso1_p115_C PF04871.13 CRK32312.1 - 0.027 14.8 33.8 0.16 12.4 13.8 2.3 1 1 2 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region CENP-K PF11802.8 CRK32312.1 - 0.031 13.8 22.4 0.13 11.8 22.4 1.8 1 1 0 1 1 1 0 Centromere-associated protein K TPR_MLP1_2 PF07926.12 CRK32312.1 - 0.035 14.2 37.6 1.6 8.8 17.9 3.1 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein TACC_C PF05010.14 CRK32312.1 - 0.043 13.6 25.0 0.13 12.0 12.6 2.5 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal ADIP PF11559.8 CRK32312.1 - 0.047 13.8 30.3 0.17 12.0 8.2 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding SOGA PF11365.8 CRK32312.1 - 0.051 14.7 25.3 2.6 9.2 5.6 4.1 1 1 2 4 4 4 0 Protein SOGA CALCOCO1 PF07888.11 CRK32312.1 - 0.068 12.0 31.4 0.21 10.4 10.4 2.0 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like APG6_N PF17675.1 CRK32312.1 - 0.099 13.2 39.6 1.6 9.2 20.9 2.4 1 1 1 2 2 2 0 Apg6 coiled-coil region KASH_CCD PF14662.6 CRK32312.1 - 0.11 12.4 31.8 0.092 12.6 29.1 2.1 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DUF4686 PF15742.5 CRK32312.1 - 0.11 11.6 33.0 0.15 11.1 11.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4686) AAA_13 PF13166.6 CRK32312.1 - 0.11 11.1 23.8 0.057 12.1 7.7 2.1 1 1 1 2 2 2 0 AAA domain bZIP_1 PF00170.21 CRK32312.1 - 0.13 12.3 32.8 0.62 10.2 6.2 5.1 1 1 5 6 6 6 0 bZIP transcription factor DUF3287 PF11690.8 CRK32312.1 - 0.16 11.7 8.0 4.6 7.0 0.1 3.2 1 1 1 3 3 3 0 Protein of unknown function (DUF3287) KELK PF15796.5 CRK32312.1 - 0.16 12.4 31.3 0.23 11.9 3.4 3.7 2 2 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase NPV_P10 PF05531.12 CRK32312.1 - 0.17 12.3 10.9 1.6 9.2 2.1 3.1 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF4618 PF15397.6 CRK32312.1 - 0.2 11.1 23.3 3.3 7.0 23.3 3.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) BRE1 PF08647.11 CRK32312.1 - 0.2 11.8 30.7 4.1 7.6 15.2 2.5 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase TMF_DNA_bd PF12329.8 CRK32312.1 - 0.2 11.7 36.6 0.31 11.1 14.2 3.4 1 1 2 3 3 2 0 TATA element modulatory factor 1 DNA binding Jnk-SapK_ap_N PF09744.9 CRK32312.1 - 0.23 11.7 33.1 0.26 11.5 20.1 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 UPF0242 PF06785.11 CRK32312.1 - 0.23 11.5 32.1 0.47 10.5 11.1 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus HOOK PF05622.12 CRK32312.1 - 0.24 9.5 28.7 0.42 8.7 28.7 1.4 1 1 0 1 1 1 0 HOOK protein Fez1 PF06818.15 CRK32312.1 - 0.29 11.6 27.5 0.19 12.1 21.8 2.0 1 1 1 2 2 2 0 Fez1 CENP-H PF05837.12 CRK32312.1 - 0.29 11.5 25.6 2.1 8.8 14.3 2.8 1 1 2 3 3 3 0 Centromere protein H (CENP-H) Syntaxin-6_N PF09177.11 CRK32312.1 - 0.4 11.3 19.7 12 6.6 2.3 3.4 1 1 0 2 2 2 0 Syntaxin 6, N-terminal ZapB PF06005.12 CRK32312.1 - 0.41 11.1 39.3 5.5 7.5 6.0 4.1 1 1 2 3 3 3 0 Cell division protein ZapB Phage_GP20 PF06810.11 CRK32312.1 - 0.43 10.4 28.6 2.8 7.7 3.5 3.1 1 1 2 3 3 3 0 Phage minor structural protein GP20 EzrA PF06160.12 CRK32312.1 - 0.43 8.7 24.4 0.21 9.7 8.1 2.2 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA WXG100 PF06013.12 CRK32312.1 - 0.44 10.8 13.6 1.7 8.9 0.2 3.7 2 1 1 3 3 3 0 Proteins of 100 residues with WXG T3SSipB PF16535.5 CRK32312.1 - 0.44 11.0 17.5 5.6 7.4 5.4 2.9 1 1 1 2 2 2 0 Type III cell invasion protein SipB SlyX PF04102.12 CRK32312.1 - 0.52 11.0 22.9 0.89 10.2 1.7 3.9 2 1 2 4 4 4 0 SlyX GIT_CC PF16559.5 CRK32312.1 - 0.54 10.2 20.5 0.79 9.6 3.5 4.3 3 3 1 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF1664 PF07889.12 CRK32312.1 - 0.59 10.2 15.9 2 8.5 3.3 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) CASP_C PF08172.12 CRK32312.1 - 0.6 9.4 21.3 0.18 11.1 1.9 2.1 1 1 1 2 2 2 0 CASP C terminal Imm7 PF15585.6 CRK32312.1 - 0.61 10.4 5.9 4.3 7.6 0.7 2.2 2 0 0 2 2 2 0 Immunity protein 7 JIP_LZII PF16471.5 CRK32312.1 - 0.83 9.9 24.3 0.68 10.2 5.5 3.5 2 1 2 4 4 4 0 JNK-interacting protein leucine zipper II JAKMIP_CC3 PF16034.5 CRK32312.1 - 0.94 9.4 25.6 1.1 9.1 6.3 3.1 1 1 1 2 2 2 0 JAKMIP CC3 domain DUF4201 PF13870.6 CRK32312.1 - 0.99 9.1 25.2 2.9 7.6 7.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) KxDL PF10241.9 CRK32312.1 - 1.1 9.5 19.0 1.6 9.0 2.2 3.9 1 1 3 4 4 4 0 Uncharacterized conserved protein HMMR_N PF15905.5 CRK32312.1 - 1.1 8.6 32.5 2.8 7.3 32.5 1.5 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DUF3584 PF12128.8 CRK32312.1 - 1.2 6.5 27.1 2.4 5.6 27.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Atg14 PF10186.9 CRK32312.1 - 1.5 7.8 22.4 0.87 8.6 12.2 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Seryl_tRNA_N PF02403.22 CRK32312.1 - 1.5 9.0 26.6 0.94 9.7 2.7 3.2 1 1 1 2 2 1 0 Seryl-tRNA synthetase N-terminal domain DUF4407 PF14362.6 CRK32312.1 - 1.6 8.0 21.7 8.7 5.6 21.7 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) CLZ PF16526.5 CRK32312.1 - 2.3 8.7 27.0 7 7.1 2.1 3.5 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Fmp27_WPPW PF10359.9 CRK32312.1 - 2.4 6.9 23.8 0.13 11.0 8.6 2.1 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain DivIC PF04977.15 CRK32312.1 - 2.8 7.8 32.4 0.23 11.3 2.3 4.3 2 1 2 4 4 4 0 Septum formation initiator Cep57_MT_bd PF06657.13 CRK32312.1 - 2.9 8.4 22.4 0.84 10.1 1.7 3.7 1 1 3 4 4 4 0 Centrosome microtubule-binding domain of Cep57 bZIP_2 PF07716.15 CRK32312.1 - 3.1 7.9 38.9 1.3 9.1 2.0 5.5 1 1 3 5 5 5 0 Basic region leucine zipper DUF745 PF05335.13 CRK32312.1 - 3.2 7.4 20.1 0.2 11.4 4.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) PI3K_P85_iSH2 PF16454.5 CRK32312.1 - 3.5 7.2 27.8 11 5.5 1.1 2.8 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF4472 PF14739.6 CRK32312.1 - 3.6 8.4 26.3 5.4 7.8 10.1 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4472) YabA PF06156.13 CRK32312.1 - 4.4 8.0 24.5 6.1 7.5 9.6 3.2 1 1 2 3 3 3 0 Initiation control protein YabA TolA_bind_tri PF16331.5 CRK32312.1 - 4.8 7.3 23.0 0.56 10.3 1.7 4.0 2 1 2 4 4 4 0 TolA binding protein trimerisation Phage_GPO PF05929.11 CRK32312.1 - 5.1 6.6 20.5 4.8 6.7 6.8 2.0 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Fib_alpha PF08702.10 CRK32312.1 - 5.3 7.2 17.7 3.3 7.9 3.5 2.5 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF4482 PF14818.6 CRK32312.1 - 6.1 7.7 24.4 1.3 9.9 5.0 2.9 1 1 0 2 2 2 0 Domain of unknown function (DUF4482) Lectin_N PF03954.14 CRK32312.1 - 6.3 6.6 18.4 2 8.2 4.3 3.1 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain HalX PF08663.10 CRK32312.1 - 6.4 7.2 26.5 0.59 10.5 3.5 4.3 2 2 1 3 3 3 0 HalX domain DUF948 PF06103.11 CRK32312.1 - 6.9 7.0 12.8 35 4.8 2.7 3.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Neur_chan_memb PF02932.16 CRK32312.1 - 8.9 6.3 7.9 11 6.0 7.9 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region HAP1_N PF04849.13 CRK32312.1 - 9.7 5.3 31.8 91 2.1 31.8 2.8 1 1 0 1 1 1 0 HAP1 N-terminal conserved region DUF2109 PF09882.9 CRK32313.1 - 0.17 11.9 0.2 0.17 11.9 0.2 2.6 2 1 0 2 2 2 0 Predicted membrane protein (DUF2109) Connexin PF00029.19 CRK32313.1 - 0.2 11.4 2.2 3.2 7.4 1.5 2.2 2 0 0 2 2 2 0 Connexin FAM176 PF14851.6 CRK32313.1 - 0.58 9.8 7.4 0.12 12.0 1.8 2.1 2 0 0 2 2 2 0 FAM176 family MAP17 PF15807.5 CRK32313.1 - 0.61 10.3 4.2 0.21 11.8 0.4 1.9 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 NARP1 PF12569.8 CRK32313.1 - 6.6 5.5 16.9 5.2 5.9 14.0 1.8 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 HET PF06985.11 CRK32314.1 - 7.2e-28 97.8 0.1 1.1e-27 97.1 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Abhydrolase_3 PF07859.13 CRK32315.1 - 0.0043 16.9 0.0 0.0043 16.9 0.0 2.5 2 1 0 2 2 2 1 alpha/beta hydrolase fold PRP9_N PF16958.5 CRK32315.1 - 0.071 13.1 0.4 0.1 12.6 0.4 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor PRP9 N-terminus PTPA PF03095.15 CRK32316.1 - 1.7e-06 27.7 0.1 2.1e-06 27.5 0.1 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein EamA PF00892.20 CRK32317.1 - 1.7e-05 25.0 15.8 2e-05 24.8 15.8 1.1 1 0 0 1 1 1 1 EamA-like transporter family Spore_YhaL PF14147.6 CRK32317.1 - 0.14 11.9 0.2 0.14 11.9 0.2 2.3 3 0 0 3 3 3 0 Sporulation protein YhaL Heme_oxygenase PF01126.20 CRK32318.1 - 1.2e-08 35.0 0.0 1.1e-07 31.8 0.0 2.1 2 0 0 2 2 2 1 Heme oxygenase WD40 PF00400.32 CRK32319.1 - 2e-14 53.8 5.8 0.0019 19.0 0.2 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK32319.1 - 1.5e-09 38.0 0.2 0.037 14.3 0.0 4.7 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CRK32319.1 - 0.37 9.7 0.6 3.6 6.5 0.0 2.5 2 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein FtsJ PF01728.19 CRK32320.1 - 1.1e-53 181.9 0.0 2e-53 181.1 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 CRK32320.1 - 1.2e-52 178.0 4.0 1.2e-52 178.0 4.0 4.7 5 0 0 5 5 5 2 Domain of unknown function (DUF3381) Spb1_C PF07780.12 CRK32320.1 - 1.5e-36 126.0 21.1 5.1e-32 111.2 14.2 5.0 4 1 1 5 5 5 2 Spb1 C-terminal domain Ustilago_mating PF05722.12 CRK32320.1 - 0.00075 19.1 5.8 0.0017 17.9 5.8 1.6 1 0 0 1 1 1 1 Ustilago B locus mating-type protein FMN_dh PF01070.18 CRK32323.1 - 7.9e-46 156.7 0.5 9.3e-46 156.4 0.5 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DUF4202 PF13875.6 CRK32324.1 - 8.3e-76 254.0 0.1 9.4e-76 253.9 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) AAA_lid_2 PF17863.1 CRK32324.1 - 0.028 14.3 1.3 0.065 13.1 1.3 1.7 1 0 0 1 1 1 0 AAA lid domain BUD22 PF09073.10 CRK32325.1 - 0.8 9.0 43.2 0.08 12.3 7.0 2.1 2 0 0 2 2 2 0 BUD22 14-3-3 PF00244.20 CRK32326.1 - 2.2e-06 27.3 0.0 2e-05 24.2 0.0 2.0 2 0 0 2 2 2 1 14-3-3 protein Sterol-sensing PF12349.8 CRK32327.1 - 3.3e-39 134.2 7.7 6.4e-39 133.2 7.7 1.5 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 CRK32327.1 - 2.8e-12 45.6 5.9 3.9e-12 45.1 5.9 1.1 1 0 0 1 1 1 1 Patched family WD40 PF00400.32 CRK32327.1 - 0.18 12.7 1.5 0.52 11.3 0.2 2.6 2 0 0 2 2 2 0 WD domain, G-beta repeat Cupin_8 PF13621.6 CRK32328.1 - 6e-65 219.5 0.0 9.3e-65 218.8 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Epimerase PF01370.21 CRK32328.1 - 3.9e-12 46.2 0.2 2.1e-11 43.7 0.2 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Cupin_4 PF08007.12 CRK32328.1 - 2.2e-06 27.4 0.0 0.0011 18.5 0.0 2.3 2 0 0 2 2 2 2 Cupin superfamily protein NAD_binding_10 PF13460.6 CRK32328.1 - 2.9e-05 24.0 0.0 5.8e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 CRK32328.1 - 4.2e-05 23.1 0.1 0.00066 19.2 0.0 2.3 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 CRK32328.1 - 0.00011 21.4 0.0 0.03 13.5 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein NmrA PF05368.13 CRK32328.1 - 0.00013 21.6 0.1 0.00029 20.5 0.1 1.5 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 CRK32328.1 - 0.00054 19.0 0.0 0.0062 15.6 0.0 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family THUMP PF02926.17 CRK32328.1 - 0.024 14.7 0.0 0.066 13.3 0.0 1.7 1 1 0 1 1 1 0 THUMP domain adh_short PF00106.25 CRK32328.1 - 0.032 13.7 0.0 0.35 10.3 0.0 2.1 2 0 0 2 2 2 0 short chain dehydrogenase SET_assoc PF11767.8 CRK32329.1 - 5.2e-51 170.1 8.9 3.9e-25 87.3 0.6 3.5 3 0 0 3 3 3 2 Histone lysine methyltransferase SET associated N-SET PF11764.8 CRK32329.1 - 1.5e-39 135.9 0.0 1.5e-39 135.9 0.0 3.5 3 0 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component N SET PF00856.28 CRK32329.1 - 4.7e-18 66.2 2.9 8.2e-18 65.4 0.2 3.1 2 0 0 2 2 2 1 SET domain RRM_1 PF00076.22 CRK32329.1 - 0.025 14.4 1.2 0.99 9.3 0.3 3.3 2 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ADSL_C PF10397.9 CRK32329.1 - 0.29 11.7 1.4 34 5.1 0.1 2.8 3 0 0 3 3 3 0 Adenylosuccinate lyase C-terminus ATP-synt_S1 PF05827.12 CRK32330.1 - 5.8e-05 23.0 0.0 9.5e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Nop25 PF09805.9 CRK32331.1 - 2.6e-23 83.0 5.3 3.7e-23 82.5 5.3 1.2 1 0 0 1 1 1 1 Nucleolar protein 12 (25kDa) Trm112p PF03966.16 CRK32331.1 - 1.3e-14 54.5 1.3 2.3e-14 53.7 0.8 1.8 2 1 0 2 2 2 1 Trm112p-like protein Zn_ribbon_recom PF13408.6 CRK32331.1 - 0.016 15.7 0.2 0.033 14.7 0.2 1.5 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain Tropomyosin_1 PF12718.7 CRK32334.1 - 3.7e-53 179.5 32.1 4.5e-53 179.3 32.1 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 CRK32334.1 - 8.6e-08 31.8 31.9 0.0011 18.4 18.9 2.8 1 1 1 2 2 2 2 Tropomyosin FlaC_arch PF05377.11 CRK32334.1 - 0.00064 20.1 21.5 0.23 11.9 0.5 4.3 3 2 1 4 4 4 3 Flagella accessory protein C (FlaC) DUF724 PF05266.14 CRK32334.1 - 0.00074 19.4 23.4 0.019 14.8 7.8 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF724) MAD PF05557.13 CRK32334.1 - 0.0024 16.3 11.2 0.0024 16.3 11.2 2.1 1 1 1 2 2 2 1 Mitotic checkpoint protein Spc7 PF08317.11 CRK32334.1 - 0.0024 16.8 31.9 0.043 12.7 15.5 2.0 1 1 1 2 2 2 2 Spc7 kinetochore protein ATG16 PF08614.11 CRK32334.1 - 0.0026 18.0 32.1 0.52 10.5 19.5 2.4 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 CRK32334.1 - 0.0048 16.9 6.8 0.0048 16.9 6.8 2.8 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_TATA_bd PF12325.8 CRK32334.1 - 0.0051 17.0 27.2 0.041 14.1 12.8 2.3 1 1 1 2 2 2 1 TATA element modulatory factor 1 TATA binding DUF4200 PF13863.6 CRK32334.1 - 0.0084 16.5 31.8 0.14 12.6 14.4 2.3 1 1 0 2 2 2 2 Domain of unknown function (DUF4200) Alanine_zipper PF11839.8 CRK32334.1 - 0.012 15.9 6.1 2.3 8.7 1.4 3.5 2 1 1 3 3 2 0 Alanine-zipper, major outer membrane lipoprotein GAS PF13851.6 CRK32334.1 - 0.017 14.5 31.6 0.19 11.1 14.0 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Taxilin PF09728.9 CRK32334.1 - 0.019 14.1 29.5 0.13 11.4 8.0 2.1 1 1 1 2 2 2 0 Myosin-like coiled-coil protein DUF3450 PF11932.8 CRK32334.1 - 0.02 14.2 24.8 0.74 9.1 8.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) ERM PF00769.19 CRK32334.1 - 0.021 14.6 34.2 0.26 11.1 15.7 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family ADIP PF11559.8 CRK32334.1 - 0.026 14.6 29.1 0.25 11.4 8.1 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding TACC_C PF05010.14 CRK32334.1 - 0.027 14.3 24.2 0.061 13.1 11.9 2.4 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal BST2 PF16716.5 CRK32334.1 - 0.029 15.0 3.8 0.029 15.0 3.8 3.4 1 1 2 3 3 3 0 Bone marrow stromal antigen 2 CENP-K PF11802.8 CRK32334.1 - 0.035 13.7 22.2 0.098 12.2 22.2 1.7 1 1 0 1 1 1 0 Centromere-associated protein K KLRAQ PF10205.9 CRK32334.1 - 0.04 14.1 21.8 0.039 14.2 8.7 3.0 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein TPR_MLP1_2 PF07926.12 CRK32334.1 - 0.042 13.9 37.1 0.35 10.9 7.8 3.1 1 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Lebercilin PF15619.6 CRK32334.1 - 0.058 13.1 32.4 1.7 8.3 17.7 2.2 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Laminin_II PF06009.12 CRK32334.1 - 0.069 13.2 18.1 0.024 14.6 6.2 2.3 1 1 1 2 2 2 0 Laminin Domain II NPV_P10 PF05531.12 CRK32334.1 - 0.079 13.4 9.7 1.9 9.0 1.9 3.1 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Syntaxin-6_N PF09177.11 CRK32334.1 - 0.082 13.5 19.6 3.4 8.3 3.1 3.4 1 1 2 3 3 3 0 Syntaxin 6, N-terminal APG6_N PF17675.1 CRK32334.1 - 0.083 13.4 38.9 1.1 9.7 20.5 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region Phage_GP20 PF06810.11 CRK32334.1 - 0.094 12.5 28.2 0.59 9.9 3.5 3.1 1 1 2 3 3 3 0 Phage minor structural protein GP20 Uso1_p115_C PF04871.13 CRK32334.1 - 0.096 13.1 33.8 0.16 12.4 13.8 2.3 1 1 2 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region SOGA PF11365.8 CRK32334.1 - 0.11 13.7 25.0 5 8.3 6.5 4.2 1 1 2 4 4 4 0 Protein SOGA BRE1 PF08647.11 CRK32334.1 - 0.12 12.5 30.3 3.4 7.8 15.2 2.6 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase UPF0242 PF06785.11 CRK32334.1 - 0.15 12.2 31.3 0.87 9.7 13.0 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF4686 PF15742.5 CRK32334.1 - 0.15 11.2 31.6 0.097 11.8 11.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4686) DUF3287 PF11690.8 CRK32334.1 - 0.18 11.5 7.8 4 7.2 0.2 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF3287) KASH_CCD PF14662.6 CRK32334.1 - 0.19 11.6 31.4 0.21 11.4 28.5 2.1 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH bZIP_1 PF00170.21 CRK32334.1 - 0.2 11.8 31.6 1.8 8.7 7.1 5.0 1 1 4 5 5 5 0 bZIP transcription factor CALCOCO1 PF07888.11 CRK32334.1 - 0.21 10.4 30.7 0.4 9.5 9.9 2.0 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Cep57_CLD_2 PF14197.6 CRK32334.1 - 0.22 11.7 30.2 4.8 7.4 9.0 3.5 2 2 0 2 2 2 0 Centrosome localisation domain of PPC89 AAA_13 PF13166.6 CRK32334.1 - 0.22 10.1 23.5 0.092 11.4 7.9 2.0 1 1 1 2 2 2 0 AAA domain Jnk-SapK_ap_N PF09744.9 CRK32334.1 - 0.22 11.8 32.4 0.19 12.0 18.4 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF1664 PF07889.12 CRK32334.1 - 0.24 11.5 15.3 0.45 10.6 2.6 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) KxDL PF10241.9 CRK32334.1 - 0.26 11.6 18.8 0.75 10.1 0.5 3.9 1 1 3 4 4 4 0 Uncharacterized conserved protein KELK PF15796.5 CRK32334.1 - 0.39 11.2 30.3 5.4 7.5 15.6 3.7 2 2 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase HOOK PF05622.12 CRK32334.1 - 0.49 8.5 28.2 0.95 7.5 28.2 1.5 1 1 0 1 1 1 0 HOOK protein DUF4618 PF15397.6 CRK32334.1 - 0.5 9.7 22.8 9.1 5.6 22.8 3.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) CENP-H PF05837.12 CRK32334.1 - 0.52 10.7 25.1 8 6.9 17.1 2.7 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Fez1 PF06818.15 CRK32334.1 - 0.55 10.7 27.2 5.1 7.5 27.2 1.9 1 1 0 1 1 1 0 Fez1 EzrA PF06160.12 CRK32334.1 - 0.59 8.2 24.1 0.11 10.7 7.3 2.2 1 1 0 2 2 2 0 Septation ring formation regulator, EzrA GIT_CC PF16559.5 CRK32334.1 - 0.7 9.8 19.2 1 9.3 3.4 4.4 3 3 1 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor TMF_DNA_bd PF12329.8 CRK32334.1 - 1.2 9.2 37.0 0.59 10.2 14.7 3.3 1 1 2 4 4 3 0 TATA element modulatory factor 1 DNA binding WXG100 PF06013.12 CRK32334.1 - 1.2 9.4 12.9 4.8 7.5 0.1 3.7 2 1 0 3 3 3 0 Proteins of 100 residues with WXG JAKMIP_CC3 PF16034.5 CRK32334.1 - 1.2 9.0 25.3 1 9.2 6.6 3.1 1 1 2 3 3 3 0 JAKMIP CC3 domain Atg14 PF10186.9 CRK32334.1 - 1.3 8.0 22.1 0.69 8.9 11.4 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 JIP_LZII PF16471.5 CRK32334.1 - 2 8.7 24.0 0.41 10.8 5.3 3.5 2 1 2 4 4 4 0 JNK-interacting protein leucine zipper II CASP_C PF08172.12 CRK32334.1 - 2.1 7.6 21.7 0.22 10.8 1.8 2.3 1 1 1 2 2 2 0 CASP C terminal Cortex-I_coil PF09304.10 CRK32334.1 - 2.2 8.5 22.8 4.2 7.6 7.6 3.2 1 1 2 3 3 3 0 Cortexillin I, coiled coil DUF3584 PF12128.8 CRK32334.1 - 2.7 5.4 26.7 4.7 4.6 26.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) CLZ PF16526.5 CRK32334.1 - 2.8 8.4 26.4 7.3 7.0 1.7 3.5 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4472 PF14739.6 CRK32334.1 - 2.8 8.7 26.1 8.3 7.2 10.8 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4472) DUF4407 PF14362.6 CRK32334.1 - 3.3 7.0 21.2 14 4.9 21.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) SlyX PF04102.12 CRK32334.1 - 3.3 8.4 22.8 1.1 9.9 1.9 3.9 1 1 2 4 4 4 0 SlyX Phage_GPO PF05929.11 CRK32334.1 - 3.4 7.2 19.7 4.6 6.8 6.8 2.0 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Lectin_N PF03954.14 CRK32334.1 - 3.4 7.4 17.7 1.1 9.1 3.9 3.2 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain DUF745 PF05335.13 CRK32334.1 - 4 7.1 19.3 0.37 10.5 4.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Fmp27_WPPW PF10359.9 CRK32334.1 - 4.3 6.1 23.7 0.33 9.7 9.9 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain End3 PF12761.7 CRK32334.1 - 5 7.3 24.6 15 5.7 23.5 2.0 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 DivIC PF04977.15 CRK32334.1 - 5.7 6.8 32.0 0.24 11.2 2.0 4.3 2 1 2 4 4 4 0 Septum formation initiator Fib_alpha PF08702.10 CRK32334.1 - 6.6 6.9 18.0 6.2 7.0 5.4 2.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family ZapB PF06005.12 CRK32334.1 - 6.7 7.2 39.5 42 4.7 5.2 4.1 1 1 1 2 2 1 0 Cell division protein ZapB YabA PF06156.13 CRK32334.1 - 7.6 7.2 23.7 12 6.6 10.2 3.2 1 1 2 3 3 3 0 Initiation control protein YabA Seryl_tRNA_N PF02403.22 CRK32334.1 - 7.7 6.8 26.9 1.7 8.9 1.2 3.2 1 1 1 2 2 1 0 Seryl-tRNA synthetase N-terminal domain Neur_chan_memb PF02932.16 CRK32334.1 - 7.8 6.5 7.5 9.2 6.2 7.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CHDCT2 PF08074.11 CRK32334.1 - 8.1 6.6 10.6 1.8 8.7 3.4 2.1 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain PI3K_P85_iSH2 PF16454.5 CRK32334.1 - 8.6 5.9 27.0 36 3.9 0.9 2.7 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain HMMR_N PF15905.5 CRK32334.1 - 9.2 5.6 31.7 35 3.7 31.7 1.7 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Cep57_MT_bd PF06657.13 CRK32334.1 - 9.5 6.7 22.7 2.2 8.8 2.6 3.8 1 1 3 4 4 4 0 Centrosome microtubule-binding domain of Cep57 Nop25 PF09805.9 CRK32335.1 - 5.3e-39 133.8 19.0 5.3e-39 133.8 19.0 3.2 2 1 0 3 3 3 1 Nucleolar protein 12 (25kDa) Lipl32 PF12103.8 CRK32335.1 - 0.88 9.2 10.8 0.15 11.7 3.7 2.1 1 1 1 2 2 2 0 Surface lipoprotein of Spirochaetales order NARP1 PF12569.8 CRK32335.1 - 9.2 5.0 33.1 0.46 9.3 16.9 2.0 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 ATP-synt_S1 PF05827.12 CRK32336.1 - 9e-05 22.3 0.0 0.00017 21.4 0.0 1.4 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Pro_isomerase PF00160.21 CRK32337.1 - 6e-97 322.3 1.0 2.5e-47 161.1 0.1 2.2 2 0 0 2 2 2 2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Trm112p PF03966.16 CRK32337.1 - 4.2e-16 59.3 0.2 7.8e-16 58.4 0.2 1.5 1 0 0 1 1 1 1 Trm112p-like protein Syndecan PF01034.20 CRK32337.1 - 0.0044 16.9 0.1 1.9 8.4 0.1 2.6 2 0 0 2 2 2 2 Syndecan domain DUF2189 PF09955.9 CRK32337.1 - 0.0055 16.9 0.6 5.9 7.1 0.1 2.8 2 0 0 2 2 2 2 Predicted integral membrane protein (DUF2189) PDE6_gamma PF04868.12 CRK32337.1 - 0.058 13.6 0.1 22 5.4 0.0 2.7 2 0 0 2 2 2 0 Retinal cGMP phosphodiesterase, gamma subunit DUF1942 PF09167.11 CRK32337.1 - 0.06 13.3 0.0 5.7 6.9 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1942) Zn_ribbon_recom PF13408.6 CRK32337.1 - 0.083 13.4 0.2 0.16 12.5 0.2 1.4 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain Frag1 PF10277.9 CRK32337.1 - 0.097 12.2 1.3 1.2 8.6 0.1 2.6 3 0 0 3 3 3 0 Frag1/DRAM/Sfk1 family HILPDA PF15220.6 CRK32337.1 - 0.11 12.7 0.0 30 4.9 0.0 3.0 3 0 0 3 3 3 0 Hypoxia-inducible lipid droplet-associated Ribosomal_S13 PF00416.22 CRK32338.1 - 1.8e-15 57.4 0.1 2.5e-10 40.8 1.0 2.0 1 1 1 2 2 2 2 Ribosomal protein S13/S18 Ribosomal_S13 PF00416.22 CRK32339.1 - 1.7e-15 57.6 0.1 2.5e-10 40.8 1.0 2.0 1 1 1 2 2 2 2 Ribosomal protein S13/S18 Peptidase_M19 PF01244.21 CRK32340.1 - 4.2e-105 351.4 0.0 5.1e-105 351.2 0.0 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) FCH PF00611.23 CRK32341.1 - 1.9e-08 34.4 0.0 7.3e-08 32.6 0.0 1.9 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DEP PF00610.21 CRK32341.1 - 0.00012 22.1 0.0 0.00025 21.1 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Peptidase_M19 PF01244.21 CRK32342.1 - 1.8e-77 260.7 0.0 2.1e-77 260.4 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) RhoGAP PF00620.27 CRK32343.1 - 9.5e-33 113.2 3.2 2.5e-15 56.6 0.2 2.5 2 0 0 2 2 2 2 RhoGAP domain FCH PF00611.23 CRK32343.1 - 3e-07 30.6 0.0 9.5e-07 29.0 0.0 2.0 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain DEP PF00610.21 CRK32343.1 - 5.1e-07 29.7 0.0 1.1e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PI_PP_C PF18365.1 CRK32343.1 - 0.00051 20.0 0.2 1.2 9.1 0.0 2.5 2 0 0 2 2 2 2 Phosphoinositide phosphatase C-terminal domain SMC_hinge PF06470.13 CRK32343.1 - 0.049 13.9 0.0 45 4.4 0.0 4.2 3 1 1 4 4 4 0 SMC proteins Flexible Hinge Domain Phage_TAC_8 PF10666.9 CRK32343.1 - 0.055 13.7 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Phage tail assembly chaperone protein Gp14 ()A118 LmjF365940-deam PF14421.6 CRK32343.1 - 0.32 10.6 4.8 8.7 5.9 0.4 2.4 2 0 0 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases Adaptin_N PF01602.20 CRK32344.1 - 1e-130 436.8 0.0 2.2e-46 158.5 0.0 4.4 2 1 2 4 4 4 4 Adaptin N terminal region TPR_11 PF13414.6 CRK32344.1 - 3.1e-09 36.4 0.2 3.1e-05 23.5 0.2 3.5 2 1 1 3 3 3 2 TPR repeat TPR_19 PF14559.6 CRK32344.1 - 2.8e-07 30.9 0.8 2.8e-07 30.9 0.8 4.3 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 CRK32344.1 - 5.5e-05 22.8 0.2 0.0071 16.1 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 CRK32344.1 - 0.00011 22.7 6.2 0.00061 20.4 1.3 6.4 5 1 1 6 6 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 CRK32344.1 - 0.00023 21.2 1.6 0.0013 18.9 1.0 2.6 2 0 0 2 2 1 1 Tetratricopeptide repeat HEAT PF02985.22 CRK32344.1 - 0.00034 20.6 0.0 87 3.8 0.0 7.1 7 0 0 7 7 7 0 HEAT repeat TPR_8 PF13181.6 CRK32344.1 - 0.0036 17.4 0.1 0.0036 17.4 0.1 4.5 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 CRK32344.1 - 0.0038 17.1 0.9 30 4.9 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 CRK32344.1 - 0.0041 17.1 0.1 0.0041 17.1 0.1 5.6 7 0 0 7 7 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 CRK32344.1 - 0.0049 17.1 0.5 0.064 13.7 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 CRK32344.1 - 0.097 13.3 9.3 13 6.7 0.0 5.7 6 0 0 6 6 5 0 Tetratricopeptide repeat PPR PF01535.20 CRK32344.1 - 0.17 12.2 0.0 0.76 10.2 0.0 2.3 1 0 0 1 1 1 0 PPR repeat AbiEi_3 PF11459.8 CRK32344.1 - 9.9 5.8 10.2 13 5.5 0.1 3.6 4 0 0 4 4 4 0 Transcriptional regulator, AbiEi antitoxin, Type IV TA system Y_phosphatase3 PF13350.6 CRK32346.1 - 1.6e-33 116.6 0.0 2.3e-33 116.1 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 CRK32346.1 - 2.3e-06 27.3 0.1 8.4e-06 25.5 0.1 1.8 2 0 0 2 2 2 1 Tyrosine phosphatase family Myotub-related PF06602.14 CRK32346.1 - 0.0007 18.6 0.1 0.0012 17.8 0.1 1.3 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.27 CRK32346.1 - 0.0075 15.9 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 CRK32346.1 - 0.075 12.9 0.0 0.35 10.7 0.0 1.9 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Eisosome1 PF12757.7 CRK32348.1 - 2.3e-43 147.4 11.8 2.3e-43 147.4 11.8 4.9 3 2 1 4 4 4 1 Eisosome protein 1 Frag1 PF10277.9 CRK32349.1 - 4.7e-45 153.8 15.8 5.4e-45 153.6 15.8 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF998 PF06197.13 CRK32349.1 - 0.0043 16.7 19.3 0.0083 15.7 18.6 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF998) EMP70 PF02990.16 CRK32349.1 - 0.41 9.3 6.2 1.4 7.5 3.3 2.0 2 0 0 2 2 2 0 Endomembrane protein 70 Pkinase PF00069.25 CRK32350.1 - 9.6e-63 212.0 0.0 1.2e-62 211.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK32350.1 - 4.7e-33 114.6 0.0 6.8e-33 114.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CRK32350.1 - 0.015 14.7 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Sec10 PF07393.11 CRK32351.1 - 8.2e-159 530.3 0.0 1.3e-158 529.6 0.0 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec10 SNF2_N PF00176.23 CRK32351.1 - 1.2e-61 208.4 0.0 2.4e-61 207.4 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-RING_2 PF13639.6 CRK32351.1 - 9.7e-08 32.2 11.6 1.9e-07 31.3 11.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CRK32351.1 - 1.9e-07 30.8 9.0 3.4e-07 30.0 9.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CRK32351.1 - 1.4e-06 28.0 12.9 3e-06 27.0 12.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CRK32351.1 - 1.6e-06 27.9 11.5 3.2e-06 26.9 11.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) F-box-like PF12937.7 CRK32351.1 - 1.6e-06 27.9 1.1 3.9e-06 26.6 0.2 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CRK32351.1 - 2.2e-05 24.2 0.1 5.2e-05 23.0 0.1 1.6 1 0 0 1 1 1 1 F-box domain Prok-RING_4 PF14447.6 CRK32351.1 - 4.1e-05 23.3 9.1 8.4e-05 22.3 9.1 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 CRK32351.1 - 5.2e-05 23.2 5.5 0.0081 16.2 9.4 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 CRK32351.1 - 0.00013 22.2 8.7 0.00038 20.7 8.7 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 CRK32351.1 - 0.0027 17.6 11.4 0.0057 16.6 11.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 CRK32351.1 - 0.11 12.6 6.2 0.28 11.2 5.5 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger MIP-T3_C PF17749.1 CRK32351.1 - 0.15 12.0 2.3 1.1 9.2 0.1 2.6 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region zf-RING_4 PF14570.6 CRK32351.1 - 0.18 11.6 4.7 0.45 10.4 4.7 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 CRK32351.1 - 0.41 10.8 9.8 0.9 9.8 9.8 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Yuri_gagarin PF15934.5 CRK32351.1 - 0.56 10.0 3.2 0.18 11.6 0.1 1.7 2 0 0 2 2 1 0 Yuri gagarin zf-P11 PF03854.14 CRK32351.1 - 0.85 9.3 6.5 1.8 8.3 6.5 1.5 1 0 0 1 1 1 0 P-11 zinc finger IGR PF09597.10 CRK32352.1 - 1.2e-23 83.0 0.1 1.9e-23 82.3 0.1 1.4 1 0 0 1 1 1 1 IGR protein motif DUF4661 PF15576.6 CRK32352.1 - 0.038 13.9 0.1 0.082 12.8 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4661) bZIP_2 PF07716.15 CRK32353.1 - 0.02 14.9 7.6 0.043 13.9 7.6 1.6 1 0 0 1 1 1 0 Basic region leucine zipper bZIP_1 PF00170.21 CRK32353.1 - 0.12 12.5 6.0 0.22 11.6 6.0 1.4 1 0 0 1 1 1 0 bZIP transcription factor RAMP4 PF06624.12 CRK32354.1 - 3.9e-19 68.5 0.0 4.2e-19 68.4 0.0 1.0 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 DUF2200 PF09966.9 CRK32355.1 - 0.0044 17.1 0.7 0.0073 16.4 0.5 1.4 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2200) TB2_DP1_HVA22 PF03134.19 CRK32356.1 - 1.2e-27 95.6 9.8 1.9e-27 95.0 9.8 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family RFX_DNA_binding PF02257.15 CRK32357.1 - 1.5e-27 96.0 0.0 3.3e-27 94.9 0.0 1.6 1 0 0 1 1 1 1 RFX DNA-binding domain AA_kinase PF00696.28 CRK32358.1 - 8.6e-31 107.4 0.2 1.6e-30 106.5 0.2 1.4 1 0 0 1 1 1 1 Amino acid kinase family ACT_7 PF13840.6 CRK32358.1 - 5.3e-09 35.7 0.2 1.2e-08 34.7 0.2 1.6 1 0 0 1 1 1 1 ACT domain ACT PF01842.25 CRK32358.1 - 5.9e-08 32.3 0.1 1.9e-07 30.7 0.1 1.9 1 0 0 1 1 1 1 ACT domain DUF3384 PF11864.8 CRK32358.1 - 0.029 13.3 0.2 0.039 12.9 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3384) COX5A PF02284.16 CRK32359.1 - 2.7e-40 136.5 0.3 3.5e-40 136.2 0.3 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va HDA2-3 PF11496.8 CRK32360.1 - 0.016 14.4 1.7 0.051 12.7 0.1 2.4 2 0 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 Ligase_CoA PF00549.19 CRK32360.1 - 0.3 10.9 0.1 0.3 10.9 0.1 2.1 2 0 0 2 2 2 0 CoA-ligase MIEAP PF16026.5 CRK32360.1 - 3.8 7.7 9.8 9.8 6.3 1.4 2.6 2 0 0 2 2 2 0 Mitochondria-eating protein Golgin_A5 PF09787.9 CRK32361.1 - 0.97 8.8 38.3 0.031 13.7 21.1 2.3 1 1 1 2 2 2 0 Golgin subfamily A member 5 PolyA_pol PF01743.20 CRK32361.1 - 1.8 9.0 12.9 0.55 10.7 1.7 2.8 3 0 0 3 3 3 0 Poly A polymerase head domain IFT20 PF14931.6 CRK32361.1 - 6.6 6.9 31.3 1.6 8.9 8.4 2.9 1 1 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 AA_kinase PF00696.28 CRK32362.1 - 2.3e-37 128.9 0.4 4.1e-37 128.1 0.1 1.6 2 0 0 2 2 2 1 Amino acid kinase family COX5A PF02284.16 CRK32362.1 - 1.4e-17 63.6 0.0 3.4e-17 62.3 0.0 1.6 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va ACT PF01842.25 CRK32362.1 - 1.8e-12 46.8 0.2 7.3e-06 25.6 0.0 2.8 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 CRK32362.1 - 3.1e-07 30.1 2.5 0.0033 17.2 0.1 2.6 2 0 0 2 2 2 2 ACT domain RFX_DNA_binding PF02257.15 CRK32363.1 - 3.6e-26 91.6 0.0 7.3e-26 90.6 0.0 1.6 1 0 0 1 1 1 1 RFX DNA-binding domain TB2_DP1_HVA22 PF03134.19 CRK32365.1 - 1.5e-27 95.4 9.8 2.2e-27 94.8 9.8 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family COX5A PF02284.16 CRK32366.1 - 1.4e-11 44.3 0.3 1.8e-11 44.0 0.3 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va Mid1 PF12929.7 CRK32367.1 - 9.1e-131 437.0 0.5 1e-130 436.8 0.5 1.0 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 CRK32367.1 - 0.0033 18.0 5.7 0.11 13.1 1.1 2.6 2 1 0 2 2 2 2 Fz domain DUF2200 PF09966.9 CRK32368.1 - 0.0041 17.3 0.7 0.0063 16.7 0.5 1.4 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2200) RAMP4 PF06624.12 CRK32369.1 - 2.9e-19 68.9 0.0 3.1e-19 68.8 0.0 1.0 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 SMAP PF15477.6 CRK32370.1 - 9e-09 36.2 3.6 9e-09 36.2 3.6 5.0 2 1 0 3 3 3 1 Small acidic protein family bZIP_2 PF07716.15 CRK32371.1 - 0.022 14.8 7.6 0.048 13.7 7.6 1.6 1 0 0 1 1 1 0 Basic region leucine zipper bZIP_1 PF00170.21 CRK32371.1 - 0.12 12.5 6.0 0.25 11.5 6.0 1.5 1 0 0 1 1 1 0 bZIP transcription factor IGR PF09597.10 CRK32372.1 - 1e-24 86.4 0.1 5.6e-24 84.0 0.1 2.0 2 0 0 2 2 2 1 IGR protein motif DUF4661 PF15576.6 CRK32372.1 - 0.07 13.0 0.1 0.16 11.9 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4661) DUF2397 PF09660.10 CRK32372.1 - 0.075 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) SNF2_N PF00176.23 CRK32373.1 - 3.6e-30 104.9 0.0 1.4e-27 96.4 0.0 2.4 2 0 0 2 2 2 2 SNF2 family N-terminal domain zf-RING_2 PF13639.6 CRK32373.1 - 5.4e-08 33.0 12.6 1e-07 32.2 12.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CRK32373.1 - 2e-07 30.8 9.6 4.1e-07 29.8 9.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CRK32373.1 - 1.9e-06 27.6 12.3 3.7e-06 26.7 12.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CRK32373.1 - 2.4e-06 27.3 13.7 4.6e-06 26.4 13.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CRK32373.1 - 3.8e-05 23.4 9.9 7.8e-05 22.5 9.9 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 CRK32373.1 - 8e-05 22.9 9.7 8e-05 22.9 9.7 2.0 2 0 0 2 2 1 1 RING-H2 zinc finger domain Helicase_C PF00271.31 CRK32373.1 - 0.00032 21.0 0.0 0.0012 19.2 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_UBOX PF13445.6 CRK32373.1 - 0.00089 19.2 7.6 0.0026 17.7 7.6 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CRK32373.1 - 0.0017 18.3 11.2 0.0037 17.2 11.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 CRK32373.1 - 0.0059 16.6 6.9 0.014 15.4 6.0 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 CRK32373.1 - 0.11 12.3 4.7 0.29 11.0 4.7 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain MIP-T3_C PF17749.1 CRK32373.1 - 0.13 12.2 2.3 0.89 9.5 0.1 2.6 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region zf-P11 PF03854.14 CRK32373.1 - 0.26 11.0 7.0 0.62 9.8 7.0 1.6 1 0 0 1 1 1 0 P-11 zinc finger DUF3490 PF11995.8 CRK32373.1 - 0.28 11.0 1.5 2.8 7.8 0.0 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF3490) zf-C3HC4_4 PF15227.6 CRK32373.1 - 0.5 10.6 10.0 1.2 9.4 10.0 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Spectrin PF00435.21 CRK32373.1 - 6 7.4 7.8 26 5.4 0.4 2.9 2 0 0 2 2 2 0 Spectrin repeat Pkinase PF00069.25 CRK32374.1 - 9.9e-63 212.0 0.0 1.2e-62 211.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK32374.1 - 4.8e-33 114.5 0.0 7e-33 114.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CRK32374.1 - 0.013 14.9 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Frag1 PF10277.9 CRK32375.1 - 1e-43 149.4 16.0 1.2e-43 149.2 16.0 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF998 PF06197.13 CRK32375.1 - 0.017 14.7 21.2 0.028 14.0 19.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF998) EMP70 PF02990.16 CRK32375.1 - 0.47 9.1 9.2 3 6.4 4.0 2.0 2 0 0 2 2 2 0 Endomembrane protein 70 DUF3611 PF12263.8 CRK32375.1 - 0.96 9.3 21.5 0.83 9.5 2.3 3.2 1 1 1 3 3 3 0 Protein of unknown function (DUF3611) Eisosome1 PF12757.7 CRK32376.1 - 3.2e-42 143.7 11.6 3.2e-42 143.7 11.6 5.0 4 2 1 5 5 5 1 Eisosome protein 1 Y_phosphatase3 PF13350.6 CRK32377.1 - 1.4e-42 146.3 0.0 1.9e-42 145.9 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 CRK32377.1 - 1.5e-06 27.9 0.0 3.9e-06 26.6 0.0 1.7 2 0 0 2 2 2 1 Tyrosine phosphatase family Myotub-related PF06602.14 CRK32377.1 - 0.0011 18.0 0.0 0.0019 17.2 0.0 1.4 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.27 CRK32377.1 - 0.012 15.2 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DSPc PF00782.20 CRK32377.1 - 0.14 12.0 0.0 0.57 10.0 0.0 1.9 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Methyltransf_12 PF08242.12 CRK32378.1 - 2.2e-31 108.5 0.0 4.5e-14 53.0 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 CRK32378.1 - 1.6e-30 105.6 0.0 1.1e-13 51.7 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 CRK32378.1 - 1.4e-23 83.4 0.0 3.1e-10 40.6 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 CRK32378.1 - 1.4e-22 80.3 0.0 5.3e-10 39.4 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 CRK32378.1 - 3.8e-18 65.7 0.0 1.1e-07 31.7 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.18 CRK32378.1 - 3.2e-12 46.3 0.0 7.3e-05 22.2 0.0 2.2 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.6 CRK32378.1 - 1.8e-10 41.8 0.0 0.0014 19.6 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain MTS PF05175.14 CRK32378.1 - 3.2e-08 33.3 0.0 0.0058 16.2 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase small domain Methyltransf_8 PF05148.15 CRK32378.1 - 7.8e-07 29.2 0.0 0.12 12.2 0.0 3.4 2 2 0 2 2 2 2 Hypothetical methyltransferase DUF3419 PF11899.8 CRK32378.1 - 2.6e-06 26.9 0.0 0.068 12.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3419) NNMT_PNMT_TEMT PF01234.17 CRK32378.1 - 0.0001 21.6 0.0 2.9 7.0 0.0 4.1 2 2 2 4 4 4 2 NNMT/PNMT/TEMT family Methyltransf_32 PF13679.6 CRK32378.1 - 0.00094 19.2 0.0 1.9 8.5 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_16 PF10294.9 CRK32378.1 - 0.0013 18.5 0.0 1.1 9.0 0.0 2.2 2 0 0 2 2 2 2 Lysine methyltransferase TPMT PF05724.11 CRK32378.1 - 0.0079 15.9 0.0 6.2 6.4 0.0 2.9 2 2 0 2 2 2 2 Thiopurine S-methyltransferase (TPMT) DUF3242 PF11586.8 CRK32378.1 - 0.015 15.0 0.2 2.3 8.0 0.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF3242) DUF3148 PF11347.8 CRK32378.1 - 0.021 14.6 0.3 8.8 6.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3148) DUF3298 PF11738.8 CRK32378.1 - 0.034 15.2 1.1 25 6.0 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3298) UPF0181 PF03701.14 CRK32378.1 - 0.041 13.5 0.0 13 5.5 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0181) Glutaredoxin PF00462.24 CRK32378.1 - 0.086 13.1 0.0 28 5.0 0.0 2.6 2 0 0 2 2 2 0 Glutaredoxin Roc PF08477.13 CRK32378.1 - 0.087 13.0 0.6 23 5.2 0.0 2.8 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Smoothelin PF12510.8 CRK32378.1 - 0.11 12.5 0.3 7.1 6.8 0.0 2.7 2 0 0 2 2 2 0 Smoothelin cytoskeleton protein TPR_11 PF13414.6 CRK32379.1 - 6.8e-10 38.5 0.1 0.0002 21.0 0.1 3.5 2 1 1 3 3 3 3 TPR repeat TPR_19 PF14559.6 CRK32379.1 - 5.2e-06 26.9 0.2 5.2e-06 26.9 0.2 4.4 3 2 0 3 3 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 CRK32379.1 - 4.3e-05 24.0 2.6 0.0012 19.5 0.3 6.7 6 1 1 7 7 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 CRK32379.1 - 0.0015 19.0 4.4 6.6 7.6 0.0 5.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 CRK32379.1 - 0.0026 17.7 0.4 11 6.3 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 CRK32379.1 - 0.0026 17.5 0.0 1.5 8.7 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 CRK32379.1 - 0.0033 17.5 0.1 0.0033 17.5 0.1 5.3 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 CRK32379.1 - 0.0065 16.5 0.1 0.0065 16.5 0.1 6.7 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 CRK32379.1 - 0.01 16.2 0.3 0.47 10.9 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 CRK32379.1 - 0.052 13.5 0.0 1.4 8.8 0.0 2.7 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal PPR PF01535.20 CRK32379.1 - 0.08 13.2 0.0 0.28 11.5 0.0 2.0 1 0 0 1 1 1 0 PPR repeat Polyketide_cyc PF03364.20 CRK32380.1 - 1.3e-16 60.9 0.0 2e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 CRK32380.1 - 0.0048 17.2 0.0 0.0059 16.9 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Adaptin_N PF01602.20 CRK32381.1 - 8.2e-21 74.1 0.1 9.8e-21 73.9 0.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region DUF2312 PF10073.9 CRK32381.1 - 0.082 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) Phage_TAC_8 PF10666.9 CRK32382.1 - 0.051 13.9 0.0 0.082 13.2 0.0 1.3 1 0 0 1 1 1 0 Phage tail assembly chaperone protein Gp14 ()A118 DASH_Duo1 PF08651.10 CRK32382.1 - 0.11 12.2 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 DASH complex subunit Duo1 DUF4325 PF14213.6 CRK32382.1 - 0.13 12.0 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 STAS-like domain of unknown function (DUF4325) BAT PF15915.5 CRK32383.1 - 0.14 12.0 1.2 0.22 11.4 1.2 1.4 1 0 0 1 1 1 0 GAF and HTH_10 associated domain MMR_HSR1_C PF08438.10 CRK32399.1 - 8.9e-37 126.1 0.0 1.4e-36 125.5 0.0 1.3 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 CRK32399.1 - 1.2e-07 31.8 0.0 2.2e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CRK32399.1 - 0.052 13.1 0.2 0.14 11.7 0.2 1.6 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain DUF3892 PF13031.6 CRK32399.1 - 0.094 13.4 1.0 1.8 9.3 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3892) RsgA_GTPase PF03193.16 CRK32399.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase ATP-synt_C PF00137.21 CRK32404.1 - 0.00057 20.2 6.6 0.00057 20.2 6.6 2.3 2 0 0 2 2 2 2 ATP synthase subunit C MDD_C PF18376.1 CRK32405.1 - 2.4e-61 206.8 0.1 2.7e-61 206.6 0.1 1.0 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain CNH PF00780.22 CRK32407.1 - 0.028 14.0 0.0 0.039 13.6 0.0 1.2 1 0 0 1 1 1 0 CNH domain Fibrillarin PF01269.17 CRK32408.1 - 8e-44 149.4 0.0 1e-43 149.1 0.0 1.1 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 CRK32408.1 - 0.003 17.3 0.1 0.0052 16.5 0.1 1.4 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit SpoU_sub_bind PF08032.12 CRK32409.1 - 2.5e-11 43.7 0.0 3.7e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding Glyco_hydro_3_C PF01915.22 CRK32411.1 - 0.0053 16.7 0.0 0.0095 15.9 0.0 1.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain CHASE8 PF17152.4 CRK32411.1 - 0.034 14.4 0.0 0.054 13.7 0.0 1.3 1 0 0 1 1 1 0 Periplasmic sensor domain CBS PF00571.28 CRK32412.1 - 2.1e-07 31.3 0.3 5.9e-07 29.8 0.1 1.8 2 0 0 2 2 2 1 CBS domain ATPase PF06745.13 CRK32412.1 - 0.033 13.5 0.2 0.047 13.0 0.2 1.3 1 1 0 1 1 1 0 KaiC PikAIV_N PF18605.1 CRK32412.1 - 0.045 13.3 0.9 11 5.6 0.0 2.4 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain CIA30 PF08547.12 CRK32418.1 - 0.028 14.5 0.0 0.041 13.9 0.0 1.3 1 0 0 1 1 1 0 Complex I intermediate-associated protein 30 (CIA30) Sin3a_C PF16879.5 CRK32420.1 - 5.5e-19 69.0 0.1 5.5e-19 69.0 0.1 1.5 2 0 0 2 2 2 1 C-terminal domain of Sin3a protein Flavodoxin_1 PF00258.25 CRK32422.1 - 2.2e-10 40.9 0.0 4.1e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 CRK32422.1 - 0.0053 17.0 0.0 0.096 12.9 0.0 2.0 2 0 0 2 2 2 1 Flavodoxin domain GerD PF17898.1 CRK32422.1 - 0.055 13.4 0.1 0.08 12.9 0.1 1.3 1 0 0 1 1 1 0 Spore germination GerD central core domain Proteasome PF00227.26 CRK32424.1 - 1.6e-34 119.1 0.0 1.8e-34 118.9 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit KH_1 PF00013.29 CRK32425.1 - 4.9e-10 39.1 0.7 6.8e-10 38.6 0.7 1.2 1 0 0 1 1 1 1 KH domain KH_2 PF07650.17 CRK32425.1 - 0.0021 17.8 0.4 0.003 17.3 0.4 1.2 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 CRK32425.1 - 0.0074 16.1 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 KH domain HEAT_EZ PF13513.6 CRK32426.1 - 1.1e-05 25.8 0.1 0.0039 17.7 0.0 3.3 3 1 1 4 4 4 1 HEAT-like repeat HEAT_2 PF13646.6 CRK32426.1 - 7.3e-05 23.1 0.0 0.014 15.8 0.0 2.3 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.22 CRK32426.1 - 0.00074 19.6 0.4 0.036 14.3 0.0 3.0 4 0 0 4 4 4 1 HEAT repeat ParcG PF10274.9 CRK32426.1 - 0.01 16.0 0.0 0.023 14.8 0.0 1.6 1 1 1 2 2 2 1 Parkin co-regulated protein Arm PF00514.23 CRK32426.1 - 0.04 14.0 0.0 0.27 11.3 0.0 2.2 2 1 0 2 2 2 0 Armadillo/beta-catenin-like repeat Cation_ATPase_N PF00690.26 CRK32428.1 - 5.8e-18 64.3 0.0 7.1e-18 64.1 0.0 1.1 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus DUF2970 PF11174.8 CRK32428.1 - 0.022 14.6 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) Phage_Coat_A PF05357.13 CRK32429.1 - 0.23 11.3 2.3 0.42 10.4 0.0 2.1 2 0 0 2 2 2 0 Phage Coat Protein A Afi1 PF07792.12 CRK32432.1 - 1.5e-50 171.2 2.2 2.2e-50 170.6 2.2 1.3 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking Astro_capsid_p PF12226.8 CRK32432.1 - 1.5e-05 24.4 8.7 1.6e-05 24.2 8.7 1.1 1 0 0 1 1 1 1 Turkey astrovirus capsid protein Cwf_Cwc_15 PF04889.12 CRK32432.1 - 0.00048 19.9 14.2 0.00056 19.7 14.2 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Avl9 PF09794.9 CRK32432.1 - 0.00091 18.0 0.3 0.0013 17.5 0.0 1.3 2 0 0 2 2 2 1 Transport protein Avl9 Drc1-Sld2 PF11719.8 CRK32432.1 - 0.005 16.4 6.4 0.0052 16.4 6.4 1.1 1 0 0 1 1 1 1 DNA replication and checkpoint protein Nop53 PF07767.11 CRK32432.1 - 0.0082 15.6 10.4 0.011 15.2 10.4 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) DUF1168 PF06658.12 CRK32432.1 - 0.0088 15.9 11.6 0.013 15.4 11.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) Nop14 PF04147.12 CRK32432.1 - 0.009 14.3 15.1 0.0099 14.2 15.1 1.0 1 0 0 1 1 1 1 Nop14-like family BUD22 PF09073.10 CRK32432.1 - 0.017 14.5 12.7 0.019 14.3 12.7 1.1 1 0 0 1 1 1 0 BUD22 CNDH2_C PF16858.5 CRK32432.1 - 0.038 13.9 6.2 0.043 13.7 6.2 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term PPP4R2 PF09184.11 CRK32432.1 - 0.07 12.7 14.2 0.083 12.5 14.2 1.1 1 0 0 1 1 1 0 PPP4R2 Rib_recp_KP_reg PF05104.12 CRK32432.1 - 0.09 13.8 3.5 0.11 13.5 3.5 1.2 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region CSRNP_N PF16019.5 CRK32432.1 - 0.09 12.7 3.1 0.11 12.4 3.1 1.2 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus DUF4746 PF15928.5 CRK32432.1 - 0.15 11.4 7.6 0.18 11.2 7.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Paramyxo_ncap PF00973.19 CRK32432.1 - 0.16 10.9 2.7 0.18 10.7 2.7 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein TFIIF_alpha PF05793.12 CRK32432.1 - 0.27 9.8 20.0 0.32 9.6 20.0 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Rhabdo_ncap PF00945.18 CRK32432.1 - 0.37 9.6 3.8 0.51 9.2 3.8 1.2 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein PPL5 PF18168.1 CRK32432.1 - 0.74 9.0 4.8 0.93 8.7 4.8 1.1 1 0 0 1 1 1 0 Prim-pol family 5 RNA_pol_3_Rpc31 PF11705.8 CRK32432.1 - 0.75 10.0 22.6 0.96 9.7 22.6 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 TFIIA PF03153.13 CRK32432.1 - 1.5 8.7 11.7 1.7 8.5 11.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DNA_pol_phi PF04931.13 CRK32432.1 - 2.6 6.0 17.5 3.4 5.7 17.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi NPR3 PF03666.13 CRK32432.1 - 2.8 6.6 6.2 3.2 6.4 6.2 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Nucleo_P87 PF07267.11 CRK32432.1 - 3.1 6.6 11.3 3.7 6.3 11.3 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 NOA36 PF06524.12 CRK32432.1 - 3.6 6.8 20.5 4.7 6.4 20.5 1.1 1 0 0 1 1 1 0 NOA36 protein FYDLN_acid PF09538.10 CRK32432.1 - 3.9 8.2 18.1 6.6 7.5 18.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) BORCS7 PF16088.5 CRK32439.1 - 0.031 14.5 0.1 0.038 14.2 0.1 1.2 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 7 DUF349 PF03993.12 CRK32439.1 - 0.037 14.3 0.2 0.05 13.9 0.2 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) AMP-binding PF00501.28 CRK32440.1 - 1.5e-14 53.4 0.0 1.7e-14 53.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme DUF2275 PF10039.9 CRK32440.1 - 0.15 12.1 0.0 0.19 11.8 0.0 1.1 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2275) zf-UBP PF02148.19 CRK32441.1 - 2.2e-07 31.1 0.3 3.2e-07 30.6 0.3 1.2 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-CCHC PF00098.23 CRK32443.1 - 6.8e-19 67.0 21.2 2.2e-07 30.6 3.6 3.3 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_2 PF13696.6 CRK32443.1 - 7.4e-11 41.7 16.7 0.002 17.9 1.1 3.4 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_3 PF13917.6 CRK32443.1 - 1.6e-05 24.8 10.4 0.039 13.9 0.6 3.3 1 1 2 3 3 3 2 Zinc knuckle zf-C2H2_10 PF16588.5 CRK32443.1 - 0.00059 19.5 14.7 0.0063 16.2 0.2 3.2 3 0 0 3 3 3 2 C2H2 zinc-finger zf-CCHC_4 PF14392.6 CRK32443.1 - 0.011 15.4 11.9 1.2 8.9 0.4 4.2 4 0 0 4 4 4 0 Zinc knuckle Ins134_P3_kin_N PF17927.1 CRK32443.1 - 0.18 12.2 0.0 0.31 11.4 0.0 1.5 1 0 0 1 1 1 0 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain zf-CCHC_6 PF15288.6 CRK32443.1 - 2.1 8.3 14.1 0.72 9.7 1.9 3.3 1 1 2 3 3 3 0 Zinc knuckle zinc-ribbons_6 PF07191.12 CRK32443.1 - 2.8 8.0 12.0 7.1 6.7 12.0 1.7 1 1 0 1 1 1 0 zinc-ribbons ADK_lid PF05191.14 CRK32443.1 - 5.9 7.0 11.5 0.61 10.1 4.7 2.4 2 0 0 2 2 2 0 Adenylate kinase, active site lid A2L_zn_ribbon PF08792.10 CRK32443.1 - 9.5 6.1 8.2 43 4.0 0.6 3.2 3 0 0 3 3 3 0 A2L zinc ribbon domain Aldo_ket_red PF00248.21 CRK32444.1 - 4.3e-45 154.2 0.0 4.8e-45 154.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FliG_M PF14841.6 CRK32444.1 - 0.00042 20.5 0.3 0.00068 19.8 0.3 1.3 1 0 0 1 1 1 1 FliG middle domain AdoMet_MTase PF07757.13 CRK32445.1 - 7e-50 168.1 0.0 3e-37 127.4 0.0 2.3 2 0 0 2 2 2 2 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.6 CRK32445.1 - 0.045 13.7 0.0 4.1 7.4 0.0 3.0 3 0 0 3 3 3 0 Methyltransferase domain TTR-52 PF01060.23 CRK32445.1 - 0.08 13.7 0.0 30 5.4 0.0 2.6 2 0 0 2 2 2 0 Transthyretin-like family ADIP PF11559.8 CRK32446.1 - 1.7e-38 132.1 3.6 3.6e-38 131.0 3.6 1.6 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Glyco_hydro_20 PF00728.22 CRK32446.1 - 1.6e-24 86.9 0.6 4.2e-24 85.6 0.6 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain F-box-like PF12937.7 CRK32446.1 - 2.5e-09 36.9 0.1 9.8e-09 35.0 0.3 1.9 2 0 0 2 2 2 1 F-box-like Glyco_hydro_20b PF02838.15 CRK32446.1 - 3.9e-07 30.9 0.0 1.1e-06 29.4 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 F-box PF00646.33 CRK32446.1 - 5.9e-05 22.8 0.1 0.00022 21.0 0.1 2.0 1 0 0 1 1 1 1 F-box domain TPR_1 PF00515.28 CRK32446.1 - 0.0021 17.8 0.6 4.2 7.3 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat Golgin_A5 PF09787.9 CRK32446.1 - 0.0031 17.0 0.8 0.0031 17.0 0.8 1.6 2 0 0 2 2 2 1 Golgin subfamily A member 5 DUF3760 PF12586.8 CRK32446.1 - 0.038 14.2 0.2 0.11 12.6 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3760) TPR_2 PF07719.17 CRK32446.1 - 0.046 13.9 3.8 29 5.1 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 CRK32446.1 - 0.11 13.4 1.8 0.63 11.0 0.5 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3584 PF12128.8 CRK32446.1 - 0.71 7.3 8.9 1.6 6.2 8.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Muted PF14942.6 CRK32446.1 - 0.87 9.9 3.6 1.7 9.0 0.1 2.5 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein Fez1 PF06818.15 CRK32446.1 - 1.1 9.7 8.7 1.2 9.5 4.2 2.2 1 1 1 2 2 2 0 Fez1 SEC-C PF02810.15 CRK32446.1 - 1.6 8.7 6.0 4.2 7.4 6.0 1.8 1 0 0 1 1 1 0 SEC-C motif TPR_MLP1_2 PF07926.12 CRK32446.1 - 4.6 7.3 15.4 1.1 9.4 0.7 2.9 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein TMF_DNA_bd PF12329.8 CRK32446.1 - 6.6 6.8 8.4 0.45 10.5 2.7 2.1 2 0 0 2 2 1 0 TATA element modulatory factor 1 DNA binding ADIP PF11559.8 CRK32447.1 - 3.2e-38 131.2 3.8 3.2e-38 131.2 3.8 2.0 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding Golgin_A5 PF09787.9 CRK32447.1 - 0.0013 18.3 1.3 0.0013 18.3 1.3 1.9 2 0 0 2 2 2 1 Golgin subfamily A member 5 DUF4686 PF15742.5 CRK32447.1 - 0.0092 15.2 0.5 0.025 13.7 0.5 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4686) Fez1 PF06818.15 CRK32447.1 - 0.07 13.6 9.2 0.48 10.9 4.7 2.6 1 1 0 2 2 2 0 Fez1 TTRAP PF14203.6 CRK32447.1 - 0.074 13.0 0.0 0.23 11.5 0.0 1.8 1 0 0 1 1 1 0 Putative tranposon-transfer assisting protein Muted PF14942.6 CRK32447.1 - 0.13 12.6 2.4 1.1 9.6 0.1 2.5 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein DUF3584 PF12128.8 CRK32447.1 - 0.14 9.6 8.3 0.35 8.3 8.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF724 PF05266.14 CRK32447.1 - 1 9.2 3.9 1.9 8.3 1.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Phage_GP20 PF06810.11 CRK32447.1 - 1.4 8.7 4.5 16 5.3 4.6 2.4 1 1 0 1 1 1 0 Phage minor structural protein GP20 TMF_DNA_bd PF12329.8 CRK32447.1 - 2.2 8.3 9.5 0.13 12.3 2.1 2.8 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF641 PF04859.12 CRK32447.1 - 2.7 8.4 8.2 19 5.6 2.2 3.5 3 1 1 4 4 4 0 Plant protein of unknown function (DUF641) Spc7 PF08317.11 CRK32447.1 - 3.1 6.6 7.5 1.3 7.9 4.0 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein APG6_N PF17675.1 CRK32447.1 - 8.7 6.9 8.5 1.1 9.8 2.4 2.5 2 1 0 2 2 2 0 Apg6 coiled-coil region AdoMet_MTase PF07757.13 CRK32448.1 - 2.9e-34 117.7 0.0 4.4e-34 117.2 0.0 1.3 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase PP2C PF00481.21 CRK32450.1 - 3.4e-22 79.3 0.0 3.8e-22 79.2 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C AARP2CN PF08142.12 CRK32451.1 - 1.3e-17 63.6 0.0 2.5e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 AARP2CN (NUC121) domain DUF4357 PF14267.6 CRK32451.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4357) Fungal_trans PF04082.18 CRK32458.1 - 5.5e-23 81.3 0.3 6e-23 81.2 0.3 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain TPR_17 PF13431.6 CRK32461.1 - 1.9e-10 40.4 0.0 0.024 15.0 0.0 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 CRK32461.1 - 3.3e-10 40.5 0.2 3.3e-08 34.0 0.8 2.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CRK32461.1 - 1.4e-08 34.2 0.1 0.017 15.2 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 CRK32461.1 - 1.5e-07 30.9 0.0 0.011 15.5 0.0 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 CRK32461.1 - 0.00028 21.5 0.4 0.4 11.6 0.4 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 CRK32461.1 - 0.00064 20.2 0.0 0.0036 17.8 0.1 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 CRK32461.1 - 0.0025 17.4 0.0 1.5 8.6 0.0 2.9 2 1 1 3 3 3 1 TPR repeat Coatomer_WDAD PF04053.14 CRK32461.1 - 0.0042 16.2 0.0 0.0052 15.9 0.0 1.1 1 0 0 1 1 1 1 Coatomer WD associated region TPR_8 PF13181.6 CRK32461.1 - 0.0053 16.9 0.0 0.76 10.1 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 CRK32461.1 - 0.018 15.4 0.3 42 4.5 0.1 2.2 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_4 PF07721.14 CRK32461.1 - 0.02 15.5 3.4 0.5 11.1 0.3 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4192 PF13830.6 CRK32461.1 - 0.038 14.0 0.3 0.044 13.9 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) AAA_5 PF07728.14 CRK32465.1 - 3.3e-19 69.3 0.0 3.5e-19 69.2 0.0 1.0 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 CRK32465.1 - 1.1e-10 41.5 0.0 1.3e-10 41.3 0.0 1.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 CRK32465.1 - 5.4e-07 30.1 0.0 7.3e-07 29.7 0.0 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Dynein_heavy PF03028.15 CRK32465.1 - 1.3e-05 25.2 0.0 0.00026 21.1 0.0 2.1 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Mg_chelatase PF01078.21 CRK32465.1 - 2.1e-05 24.0 0.1 0.11 11.9 0.0 2.1 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 CRK32465.1 - 0.00011 22.7 0.0 0.00014 22.5 0.0 1.2 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CRK32465.1 - 0.00045 20.3 0.0 0.00062 19.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CRK32465.1 - 0.00065 19.5 0.0 0.00099 18.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CRK32465.1 - 0.001 19.3 0.0 0.0025 18.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CRK32465.1 - 0.0021 18.3 0.1 0.0069 16.7 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CRK32465.1 - 0.0022 18.4 0.5 0.013 15.9 0.1 1.9 1 1 1 2 2 2 1 AAA ATPase domain NACHT PF05729.12 CRK32465.1 - 0.0025 17.8 0.0 0.0038 17.2 0.0 1.2 1 0 0 1 1 1 1 NACHT domain AAA_28 PF13521.6 CRK32465.1 - 0.0025 18.1 0.4 0.0031 17.8 0.4 1.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 CRK32465.1 - 0.0059 16.4 0.0 0.035 13.9 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 CRK32465.1 - 0.0071 15.9 0.0 0.045 13.3 0.0 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_19 PF13245.6 CRK32465.1 - 0.022 15.1 0.6 0.2 12.0 0.2 2.0 1 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 CRK32465.1 - 0.027 14.4 0.1 0.054 13.4 0.1 1.5 2 0 0 2 2 2 0 NTPase AAA_25 PF13481.6 CRK32465.1 - 0.032 13.8 0.0 0.051 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 CRK32465.1 - 0.043 13.5 0.0 0.057 13.1 0.0 1.4 1 1 0 1 1 1 0 IstB-like ATP binding protein TsaE PF02367.17 CRK32465.1 - 0.045 13.8 0.0 0.07 13.1 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Viral_helicase1 PF01443.18 CRK32465.1 - 0.064 13.0 0.0 0.08 12.7 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Sigma54_activat PF00158.26 CRK32465.1 - 0.072 12.8 0.0 0.085 12.6 0.0 1.1 1 0 0 1 1 1 0 Sigma-54 interaction domain SRP54 PF00448.22 CRK32465.1 - 0.097 12.3 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain RNA_helicase PF00910.22 CRK32465.1 - 0.097 13.1 0.0 0.12 12.8 0.0 1.4 1 1 0 1 1 1 0 RNA helicase ArsA_ATPase PF02374.15 CRK32465.1 - 0.099 11.8 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Anion-transporting ATPase AAA_6 PF12774.7 CRK32465.1 - 0.11 11.5 0.0 1 8.3 0.0 1.9 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region CPT PF07931.12 CRK32465.1 - 0.11 12.4 0.0 0.15 11.9 0.0 1.4 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein CbiA PF01656.23 CRK32465.1 - 0.11 12.6 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_29 PF13555.6 CRK32465.1 - 0.11 12.2 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ploopntkinase3 PF18751.1 CRK32465.1 - 0.12 12.2 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Zeta_toxin PF06414.12 CRK32465.1 - 0.14 11.4 0.1 0.45 9.8 0.0 1.8 2 1 0 2 2 2 0 Zeta toxin RsgA_GTPase PF03193.16 CRK32465.1 - 0.16 11.9 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase dNK PF01712.19 CRK32465.1 - 0.16 11.8 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Deoxynucleoside kinase ATP_bind_1 PF03029.17 CRK32465.1 - 0.17 11.7 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 CRK32465.1 - 0.17 11.6 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain RdRP PF05183.12 CRK32475.1 - 0.17 10.5 0.0 0.17 10.5 0.0 1.0 1 0 0 1 1 1 0 RNA dependent RNA polymerase Peptidase_S26 PF10502.9 CRK32475.1 - 0.19 11.5 0.0 0.19 11.5 0.0 1.1 1 0 0 1 1 1 0 Signal peptidase, peptidase S26 Mt_ATP-synt_B PF05405.14 CRK32477.1 - 3.9e-26 91.6 0.0 4.9e-26 91.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Secretogranin_V PF05281.11 CRK32478.1 - 0.022 14.4 0.0 0.028 14.1 0.0 1.1 1 0 0 1 1 1 0 Neuroendocrine protein 7B2 precursor (Secretogranin V) BCAS2 PF05700.11 CRK32480.1 - 7.9e-43 146.6 3.7 8.6e-43 146.4 3.7 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) TMF_TATA_bd PF12325.8 CRK32480.1 - 0.014 15.6 0.2 0.031 14.5 0.2 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Zn_clus PF00172.18 CRK32481.1 - 0.027 14.6 15.4 0.045 13.9 15.4 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MnhB PF04039.13 CRK32482.1 - 0.0028 17.9 3.0 0.005 17.1 3.0 1.4 1 0 0 1 1 1 1 Domain related to MnhB subunit of Na+/H+ antiporter adh_short PF00106.25 CRK32483.1 - 7.3e-22 77.8 0.0 8e-21 74.4 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK32483.1 - 9.7e-13 48.2 0.1 3.7e-12 46.3 0.1 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK32483.1 - 9.6e-05 22.4 0.1 0.00018 21.4 0.1 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 CRK32483.1 - 0.0045 16.5 0.0 0.006 16.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Phage_RpbA PF10789.9 CRK32483.1 - 0.07 13.2 0.1 0.23 11.6 0.0 1.7 2 0 0 2 2 2 0 Phage RNA polymerase binding, RpbA GFO_IDH_MocA PF01408.22 CRK32484.1 - 3.3e-22 79.6 1.3 4.3e-22 79.2 0.3 1.7 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 CRK32484.1 - 1.7e-07 31.2 0.0 3.6e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 CRK32484.1 - 0.00013 22.6 0.2 0.00029 21.5 0.2 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain AAA_33 PF13671.6 CRK32484.1 - 0.00065 19.9 0.1 0.012 15.7 0.0 2.3 1 1 1 2 2 2 1 AAA domain Semialdhyde_dh PF01118.24 CRK32484.1 - 0.0073 16.7 0.1 0.016 15.6 0.1 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 CRK32484.1 - 0.11 12.6 0.1 0.24 11.5 0.1 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus CBP_BcsQ PF06564.12 CRK32484.1 - 0.15 11.5 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsQ Inositol_P PF00459.25 CRK32485.1 - 1.4e-21 77.2 0.1 5.9e-21 75.2 0.1 1.9 1 1 0 1 1 1 1 Inositol monophosphatase family FAD_binding_4 PF01565.23 CRK32487.1 - 4.2e-11 42.7 1.3 5.3e-11 42.4 0.4 1.7 2 0 0 2 2 2 1 FAD binding domain DUF4907 PF16250.5 CRK32487.1 - 0.13 12.1 0.1 0.35 10.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4907) Ysc84 PF04366.12 CRK32488.1 - 7.1e-32 109.9 0.1 1.3e-31 109.1 0.1 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator NAD_binding_1 PF00175.21 CRK32489.1 - 6e-07 30.1 0.0 1.4e-06 28.9 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Helicase_C PF00271.31 CRK32491.1 - 1.4e-16 60.8 0.1 1.7e-16 60.5 0.1 1.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 CRK32491.1 - 2.2e-06 27.1 0.0 2.9e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase TK PF00265.18 CRK32491.1 - 0.063 13.2 0.0 0.076 12.9 0.0 1.2 1 0 0 1 1 1 0 Thymidine kinase Peptidase_M48 PF01435.18 CRK32494.1 - 0.1 12.3 0.0 0.29 10.9 0.0 1.6 2 0 0 2 2 2 0 Peptidase family M48 G_glu_transpept PF01019.21 CRK32495.1 - 1.3e-23 83.6 0.0 1.4e-23 83.5 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Peptidase_M16_C PF05193.21 CRK32497.1 - 7e-11 42.5 0.0 9.9e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase M16 inactive domain BMC PF00936.19 CRK32497.1 - 0.034 14.1 0.2 0.077 13.0 0.2 1.6 1 0 0 1 1 1 0 BMC domain PBP PF01161.20 CRK32497.1 - 0.094 13.0 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Phosphatidylethanolamine-binding protein FtsX PF02687.21 CRK32500.1 - 0.0033 17.8 3.1 0.0066 16.9 3.1 1.4 1 0 0 1 1 1 1 FtsX-like permease family SdpI PF13630.6 CRK32500.1 - 0.12 12.5 6.9 0.49 10.6 0.1 2.3 2 0 0 2 2 2 0 SdpI/YhfL protein family DUF4079 PF13301.6 CRK32500.1 - 0.25 11.5 3.9 0.28 11.3 3.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4079) Proteasome PF00227.26 CRK32502.1 - 5.2e-19 68.5 0.0 5.9e-19 68.3 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit RRM_occluded PF16842.5 CRK32503.1 - 5e-16 58.3 0.0 1.7e-15 56.6 0.0 1.9 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_1 PF00076.22 CRK32503.1 - 0.0037 17.1 0.0 0.0089 15.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RHD3 PF05879.12 CRK32504.1 - 6.9e-70 236.1 1.8 7.6e-70 236.0 1.8 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 CRK32504.1 - 1.3e-05 24.6 0.1 1.5e-05 24.4 0.1 1.1 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain UCH PF00443.29 CRK32505.1 - 9.5e-17 61.3 0.0 1.1e-16 61.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CRK32505.1 - 0.014 15.0 0.0 0.016 14.8 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Sugar_tr PF00083.24 CRK32506.1 - 6.1e-33 114.4 5.8 6.7e-33 114.2 5.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK32506.1 - 4.9e-07 29.0 7.7 5.5e-07 28.8 7.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily HisKA_3 PF07730.13 CRK32508.1 - 0.011 16.3 1.9 0.012 16.2 1.7 1.3 1 1 0 1 1 1 0 Histidine kinase Med30 PF11315.8 CRK32508.1 - 0.016 15.4 0.9 0.017 15.3 0.9 1.1 1 0 0 1 1 1 0 Mediator complex subunit 30 ZapD PF07072.11 CRK32508.1 - 0.02 14.6 2.1 0.022 14.5 2.1 1.0 1 0 0 1 1 1 0 Cell division protein YgaB PF14182.6 CRK32508.1 - 0.023 15.1 2.5 0.025 15.0 2.5 1.1 1 0 0 1 1 1 0 YgaB-like protein Laminin_I PF06008.14 CRK32508.1 - 0.046 13.4 4.9 0.05 13.3 4.9 1.0 1 0 0 1 1 1 0 Laminin Domain I APG6_N PF17675.1 CRK32508.1 - 0.051 14.1 7.5 0.057 14.0 7.5 1.0 1 0 0 1 1 1 0 Apg6 coiled-coil region CaMBD PF02888.16 CRK32508.1 - 0.061 13.5 3.1 0.095 12.9 3.1 1.4 1 1 0 1 1 1 0 Calmodulin binding domain RGS_DHEX PF18148.1 CRK32508.1 - 0.088 12.9 2.1 0.12 12.6 2.1 1.2 1 0 0 1 1 1 0 Regulator of G-protein signalling DHEX domain DASH_Dam1 PF08653.10 CRK32508.1 - 0.091 12.6 0.5 0.47 10.3 0.1 1.9 2 0 0 2 2 2 0 DASH complex subunit Dam1 DUF5446 PF17522.2 CRK32508.1 - 0.097 12.9 1.7 0.4 10.9 1.7 1.9 1 1 0 1 1 1 0 Family of unknown function (DUF5446) RapA_C PF12137.8 CRK32508.1 - 0.13 11.3 3.2 0.14 11.1 3.2 1.0 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal KxDL PF10241.9 CRK32508.1 - 0.19 12.0 4.3 0.74 10.1 4.2 1.7 1 1 1 2 2 2 0 Uncharacterized conserved protein Reticulon PF02453.17 CRK32508.1 - 0.31 11.0 0.2 0.33 10.9 0.2 1.0 1 0 0 1 1 1 0 Reticulon Fzo_mitofusin PF04799.13 CRK32508.1 - 0.36 10.4 3.2 0.4 10.2 3.2 1.0 1 0 0 1 1 1 0 fzo-like conserved region DUF883 PF05957.13 CRK32508.1 - 0.44 11.2 4.6 0.46 11.1 4.6 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) XhlA PF10779.9 CRK32508.1 - 2.5 8.4 6.4 4.6 7.5 5.4 1.8 1 1 1 2 2 2 0 Haemolysin XhlA HpcH_HpaI PF03328.14 CRK32509.1 - 5.2e-16 58.4 0.3 5.9e-16 58.3 0.3 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family MFS_1 PF07690.16 CRK32512.1 - 2.6e-37 128.6 24.8 5.4e-35 120.9 24.1 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily YfhO PF09586.10 CRK32512.1 - 0.17 10.1 2.8 0.19 10.0 1.4 1.7 2 0 0 2 2 2 0 Bacterial membrane protein YfhO Phage_holin_2_3 PF16080.5 CRK32512.1 - 0.4 10.5 2.5 28 4.6 0.0 3.2 2 0 0 2 2 2 0 Bacteriophage holin family HP1 Peptidase_M50B PF13398.6 CRK32513.1 - 1.9e-25 89.7 16.3 2.9e-25 89.1 16.3 1.3 1 0 0 1 1 1 1 Peptidase M50B-like TctB PF07331.11 CRK32513.1 - 0.014 15.7 7.7 0.05 13.9 4.3 2.2 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family DUF3506 PF12014.8 CRK32515.1 - 2.8e-53 179.6 0.0 2.9e-52 176.4 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3506) F-box-like PF12937.7 CRK32515.1 - 7.5e-05 22.5 0.4 0.00022 21.0 0.4 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CRK32515.1 - 0.00069 19.4 0.3 0.0017 18.2 0.3 1.7 1 0 0 1 1 1 1 F-box domain SMN PF06003.12 CRK32515.1 - 0.11 11.7 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) ABC_membrane PF00664.23 CRK32516.1 - 2.1e-84 283.4 41.5 4.9e-45 154.3 9.6 4.1 4 0 0 4 4 4 2 ABC transporter transmembrane region ABC_tran PF00005.27 CRK32516.1 - 6.4e-46 156.3 0.0 4.6e-29 101.7 0.0 2.8 3 0 0 3 3 2 2 ABC transporter MFS_1 PF07690.16 CRK32516.1 - 1.2e-35 123.1 22.9 1.2e-35 123.1 22.9 5.6 6 3 1 7 7 5 1 Major Facilitator Superfamily Polysacc_synt_4 PF04669.13 CRK32516.1 - 2.3e-19 69.7 0.8 1.5e-18 67.0 0.8 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis RsgA_GTPase PF03193.16 CRK32516.1 - 8.2e-08 32.3 0.0 0.0026 17.7 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 CRK32516.1 - 1.3e-07 31.3 0.7 0.028 14.2 0.0 3.0 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 CRK32516.1 - 2.1e-06 27.3 1.4 0.012 15.1 0.0 3.6 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CRK32516.1 - 1.5e-05 25.4 0.0 0.21 12.0 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 CRK32516.1 - 0.00013 22.3 0.1 0.97 9.7 0.1 3.1 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 CRK32516.1 - 0.00048 20.2 2.9 1 9.5 0.0 3.2 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_23 PF13476.6 CRK32516.1 - 0.0013 19.3 0.3 1 9.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 CRK32516.1 - 0.0013 18.6 0.0 5.8 6.6 0.0 3.4 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_24 PF13479.6 CRK32516.1 - 0.0058 16.4 0.0 1.9 8.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CRK32516.1 - 0.0091 16.2 0.0 4.3 7.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 CRK32516.1 - 0.018 15.2 3.3 3.7 7.6 0.5 2.6 2 0 0 2 2 2 0 Helicase HerA, central domain RNA_helicase PF00910.22 CRK32516.1 - 0.024 15.0 0.1 14 6.1 0.0 3.0 3 0 0 3 3 2 0 RNA helicase AAA_25 PF13481.6 CRK32516.1 - 0.029 13.9 0.0 11 5.5 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 CRK32516.1 - 0.067 13.7 4.1 0.75 10.4 0.2 3.2 3 1 0 3 3 2 0 AAA domain AAA_10 PF12846.7 CRK32516.1 - 0.1 11.5 0.1 2 7.3 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain AAA_15 PF13175.6 CRK32516.1 - 0.1 12.3 0.9 3.9 7.1 0.3 2.3 2 0 0 2 2 2 0 AAA ATPase domain NACHT PF05729.12 CRK32516.1 - 0.12 12.3 2.0 14 5.6 0.1 3.1 3 0 0 3 3 3 0 NACHT domain Ribosomal_60s PF00428.19 CRK32516.1 - 0.3 11.7 4.5 1 10.0 4.5 1.9 1 0 0 1 1 1 0 60s Acidic ribosomal protein MFS_1 PF07690.16 CRK32517.1 - 1.2e-42 146.1 45.7 1.2e-42 146.1 45.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK32517.1 - 2.6e-10 39.8 6.9 2.6e-10 39.8 6.9 2.6 2 1 0 3 3 3 1 Sugar (and other) transporter MFS_4 PF06779.14 CRK32517.1 - 1.5e-07 31.0 5.7 1.5e-07 31.0 5.7 2.2 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB BT1 PF03092.16 CRK32517.1 - 0.0067 14.7 0.4 0.05 11.8 0.1 2.2 2 0 0 2 2 2 1 BT1 family Protocadherin PF08374.11 CRK32517.1 - 0.19 11.7 1.4 5.4 6.9 0.0 2.6 3 0 0 3 3 3 0 Protocadherin MSP1b PF03429.13 CRK32518.1 - 0.0014 16.9 0.2 1.2 7.1 0.0 2.4 3 0 0 3 3 3 2 Major surface protein 1B Glft2_N PF17994.1 CRK32518.1 - 0.0016 18.4 0.3 2.6 8.0 0.0 2.4 2 0 0 2 2 2 2 Galactofuranosyltransferase 2 N-terminal Transposase_28 PF04195.12 CRK32518.1 - 0.014 15.6 0.6 13 6.1 0.1 3.2 2 0 0 2 2 2 0 Putative gypsy type transposon Sdh5 PF03937.16 CRK32518.1 - 0.09 12.8 0.4 42 4.2 0.1 3.5 4 0 0 4 4 4 0 Flavinator of succinate dehydrogenase PSCyt1 PF07635.11 CRK32518.1 - 0.16 12.5 3.2 22 5.8 0.2 3.2 2 0 0 2 2 2 0 Planctomycete cytochrome C Glyco_hydro_61 PF03443.14 CRK32520.1 - 7.7e-33 114.2 0.0 1.1e-24 87.5 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 61 SprB PF13573.6 CRK32520.1 - 0.095 12.5 0.6 0.93 9.3 0.1 2.3 2 0 0 2 2 2 0 SprB repeat PK PF00224.21 CRK32521.1 - 3.1e-150 499.9 3.8 4.5e-150 499.3 3.8 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain Glyco_hydro_61 PF03443.14 CRK32521.1 - 2.8e-46 158.0 0.0 6.1e-46 157.0 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 PK_C PF02887.16 CRK32521.1 - 1.1e-36 125.6 0.0 4.2e-36 123.7 0.0 2.0 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 CRK32521.1 - 0.00025 20.3 0.4 0.00073 18.7 0.3 1.8 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family DUF1748 PF08520.10 CRK32522.1 - 2e-33 114.1 0.0 2.5e-33 113.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) Seryl_tRNA_N PF02403.22 CRK32523.1 - 0.0022 18.2 1.2 0.014 15.6 1.2 2.5 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain DUF465 PF04325.13 CRK32523.1 - 0.031 14.3 0.1 0.13 12.3 0.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF465) RasGAP_C PF03836.15 CRK32523.1 - 0.09 12.9 0.1 0.98 9.6 0.3 2.4 2 0 0 2 2 2 0 RasGAP C-terminus Syntaxin-6_N PF09177.11 CRK32523.1 - 0.2 12.2 4.1 11 6.7 0.7 3.1 3 1 0 3 3 3 0 Syntaxin 6, N-terminal TBCC_N PF16752.5 CRK32523.1 - 0.27 11.7 4.7 11 6.5 0.0 3.2 4 0 0 4 4 4 0 Tubulin-specific chaperone C N-terminal domain Spc7 PF08317.11 CRK32523.1 - 0.39 9.6 6.9 0.07 12.0 3.0 1.7 2 0 0 2 2 2 0 Spc7 kinetochore protein KELK PF15796.5 CRK32523.1 - 0.44 11.0 4.1 1 9.9 0.8 2.4 1 1 2 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tektin PF03148.14 CRK32523.1 - 0.57 8.9 5.4 7.5 5.2 5.1 2.5 2 0 0 2 2 2 0 Tektin family APG6_N PF17675.1 CRK32523.1 - 4.2 7.9 13.6 0.13 12.8 3.5 3.2 3 1 0 3 3 3 0 Apg6 coiled-coil region DUF465 PF04325.13 CRK32524.1 - 0.034 14.2 0.1 0.097 12.7 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF465) KELK PF15796.5 CRK32524.1 - 0.057 13.9 2.5 0.071 13.6 0.8 2.1 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase ATG16 PF08614.11 CRK32524.1 - 0.11 12.7 1.6 0.27 11.4 0.8 2.1 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) CMV_1a PF12467.8 CRK32524.1 - 0.11 12.9 0.8 2.5 8.4 1.2 2.2 2 0 0 2 2 2 0 Cucumber mosaic virus 1a protein family Tektin PF03148.14 CRK32524.1 - 0.19 10.5 1.9 1.1 8.0 0.3 2.5 3 0 0 3 3 3 0 Tektin family DivIC PF04977.15 CRK32524.1 - 7.4 6.4 5.3 13 5.6 0.7 2.7 3 0 0 3 3 3 0 Septum formation initiator WD40 PF00400.32 CRK32525.1 - 0.47 11.4 9.8 2 9.4 0.6 4.4 3 2 2 5 5 5 0 WD domain, G-beta repeat WD40 PF00400.32 CRK32526.1 - 6.5e-07 30.0 0.7 2.1e-06 28.3 0.1 2.1 2 0 0 2 2 2 1 WD domain, G-beta repeat ADH_zinc_N PF00107.26 CRK32527.1 - 5.8e-32 110.4 0.0 1e-31 109.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CRK32527.1 - 1e-10 42.8 0.0 1.8e-10 41.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CRK32527.1 - 1.1e-06 28.5 0.0 5e-06 26.4 0.0 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ACP_syn_III_C PF08541.10 CRK32527.1 - 0.097 12.9 1.7 0.43 10.8 0.7 2.4 1 1 1 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal CTD PF12815.7 CRK32528.1 - 2.9e-14 53.4 42.4 1.9e-06 28.4 6.6 4.1 2 1 1 3 3 3 2 Spt5 C-terminal nonapeptide repeat binding Spt4 KOW PF00467.29 CRK32528.1 - 3.3e-08 33.2 11.6 0.0001 22.1 2.0 4.3 4 0 0 4 4 4 2 KOW motif DUF3912 PF13051.6 CRK32528.1 - 0.00038 20.6 1.3 0.0074 16.5 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3912) DUF3006 PF11213.8 CRK32528.1 - 0.0067 16.6 0.2 0.88 9.8 0.1 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF3006) Myosin_N PF02736.19 CRK32528.1 - 1.5 8.8 6.2 16 5.4 1.5 2.9 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain Mannosyl_trans3 PF11051.8 CRK32529.1 - 0.0049 16.3 0.0 0.0079 15.6 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative Glyco_transf_8 PF01501.20 CRK32529.1 - 0.14 11.7 1.9 0.5 9.9 0.2 2.2 2 1 0 2 2 2 0 Glycosyl transferase family 8 DUF4360 PF14273.6 CRK32530.1 - 1.7e-29 103.0 1.0 1.9e-29 102.8 1.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Sugar_tr PF00083.24 CRK32531.1 - 1.2e-95 321.0 27.5 1.5e-95 320.7 27.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK32531.1 - 1.3e-19 70.4 26.3 1.3e-19 70.4 26.3 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Pam17 PF08566.10 CRK32531.1 - 0.5 10.2 2.7 0.36 10.7 0.1 2.1 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 Cauli_VI PF01693.16 CRK32532.1 - 5.5e-73 241.1 18.1 8.8e-19 67.5 0.1 4.5 4 0 0 4 4 4 4 Caulimovirus viroplasmin RNase_H PF00075.24 CRK32532.1 - 3e-40 137.7 0.5 2.1e-36 125.2 0.1 2.5 2 0 0 2 2 2 2 RNase H dCMP_cyt_deam_1 PF00383.23 CRK32532.1 - 9.6e-10 38.3 0.1 3e-08 33.5 0.0 2.4 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region GHMP_kinases_C PF08544.13 CRK32532.1 - 0.002 18.4 1.1 1.6 9.1 0.0 3.0 3 0 0 3 3 3 2 GHMP kinases C terminal MafB19-deam PF14437.6 CRK32532.1 - 0.0057 16.4 0.4 0.089 12.5 0.1 2.4 2 0 0 2 2 2 1 MafB19-like deaminase GARS_A PF01071.19 CRK32532.1 - 0.006 16.4 1.8 2 8.2 0.1 2.4 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain HEPN_AbiA_CTD PF18732.1 CRK32532.1 - 0.14 12.1 0.0 19 5.2 0.0 2.7 2 0 0 2 2 2 0 HEPN like, Abia C-terminal domain COX6B PF02297.17 CRK32532.1 - 0.19 11.9 0.4 0.52 10.6 0.4 1.7 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb GGGtGRT PF14057.6 CRK32532.1 - 2.2 7.2 8.9 6.9 5.5 1.1 2.4 2 0 0 2 2 2 0 GGGtGRT protein 6PF2K PF01591.18 CRK32533.1 - 5.4e-66 222.1 0.0 1.4e-46 158.6 0.0 2.2 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 CRK32533.1 - 7.7e-30 104.0 0.0 7.2e-24 84.6 0.0 2.6 3 0 0 3 3 3 2 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 CRK32533.1 - 0.0084 16.3 0.0 1.4 9.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain KTI12 PF08433.10 CRK32533.1 - 0.032 13.7 0.0 0.054 12.9 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 CARD PF00619.21 CRK32533.1 - 0.18 11.8 0.4 0.76 9.8 0.4 1.9 1 1 0 1 1 1 0 Caspase recruitment domain Nic96 PF04097.14 CRK32534.1 - 3.8e-146 488.1 0.0 4.8e-146 487.8 0.0 1.0 1 0 0 1 1 1 1 Nup93/Nic96 WD40 PF00400.32 CRK32534.1 - 2e-12 47.4 7.5 1.9e-05 25.3 0.1 5.0 4 0 0 4 4 4 3 WD domain, G-beta repeat Nucleoporin_FG PF13634.6 CRK32534.1 - 3.1 8.7 24.5 0.033 15.0 16.2 2.1 3 0 0 3 3 3 0 Nucleoporin FG repeat region ADH_zinc_N PF00107.26 CRK32535.1 - 3.9e-31 107.7 0.0 7e-31 106.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CRK32535.1 - 3.1e-11 44.4 0.0 5e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CRK32535.1 - 1.4e-06 28.2 0.0 5e-06 26.4 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ACP_syn_III_C PF08541.10 CRK32535.1 - 0.39 10.9 1.7 1.6 9.0 0.7 2.4 1 1 1 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Spt5_N PF11942.8 CRK32536.1 - 6.3e-36 123.3 37.8 8.3e-22 78.0 8.7 4.5 3 1 1 4 4 4 2 Spt5 transcription elongation factor, acidic N-terminal Spt5-NGN PF03439.13 CRK32536.1 - 4.9e-22 77.6 0.1 8.4e-22 76.9 0.1 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section CTD PF12815.7 CRK32536.1 - 1.1e-18 67.6 30.1 4.9e-15 55.8 15.5 4.7 1 1 3 4 4 4 3 Spt5 C-terminal nonapeptide repeat binding Spt4 KOW PF00467.29 CRK32536.1 - 8e-08 32.0 25.9 0.00026 20.8 2.0 6.6 7 0 0 7 7 7 4 KOW motif DUF3912 PF13051.6 CRK32536.1 - 0.002 18.4 1.2 0.019 15.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3912) Cornifin PF02389.15 CRK32536.1 - 0.023 14.9 2.8 0.046 13.9 2.8 1.4 1 0 0 1 1 1 0 Cornifin (SPRR) family YqgF PF14639.6 CRK32536.1 - 0.35 10.6 1.4 27 4.5 0.1 2.5 2 0 0 2 2 2 0 Holliday-junction resolvase-like of SPT6 DUF4360 PF14273.6 CRK32537.1 - 1.1e-29 103.6 1.1 1.2e-29 103.4 1.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Sugar_tr PF00083.24 CRK32538.1 - 1.1e-93 314.6 26.3 1.4e-93 314.3 26.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK32538.1 - 3.6e-20 72.2 22.7 3.6e-20 72.2 22.7 2.4 2 1 1 3 3 3 1 Major Facilitator Superfamily Pam17 PF08566.10 CRK32538.1 - 0.23 11.3 2.4 0.18 11.6 0.1 2.0 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 dCMP_cyt_deam_1 PF00383.23 CRK32539.1 - 3.5e-09 36.4 0.0 6.5e-09 35.6 0.0 1.5 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CRK32539.1 - 0.011 15.5 0.1 0.033 13.9 0.1 1.7 2 0 0 2 2 2 0 MafB19-like deaminase 6PF2K PF01591.18 CRK32540.1 - 7e-66 221.7 0.0 1.8e-46 158.2 0.0 2.2 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 CRK32540.1 - 8.1e-30 104.0 0.0 7.4e-24 84.5 0.0 2.6 3 0 0 3 3 3 2 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 CRK32540.1 - 0.0091 16.2 0.0 1.5 9.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain KTI12 PF08433.10 CRK32540.1 - 0.033 13.6 0.0 0.055 12.9 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 CARD PF00619.21 CRK32540.1 - 0.19 11.8 0.5 0.78 9.8 0.5 1.9 1 1 0 1 1 1 0 Caspase recruitment domain Nic96 PF04097.14 CRK32542.1 - 9.6e-225 747.7 0.0 1.2e-224 747.4 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Nucleoporin_FG PF13634.6 CRK32542.1 - 5.2e-06 27.2 115.4 0.42 11.5 17.6 5.2 3 1 1 4 4 4 1 Nucleoporin FG repeat region JmjC PF02373.22 CRK32543.1 - 1.1e-10 42.0 0.1 5.2e-10 39.8 0.1 2.2 2 1 0 2 2 2 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.9 CRK32543.1 - 2.9e-09 37.0 10.2 2.9e-09 37.0 10.2 2.5 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.11 CRK32543.1 - 0.0053 16.4 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Ribosom_S12_S23 PF00164.25 CRK32545.1 - 2.3e-49 165.8 0.6 4.5e-49 164.8 0.6 1.5 1 0 0 1 1 1 1 Ribosomal protein S12/S23 JmjC PF02373.22 CRK32545.1 - 1.8e-10 41.2 0.1 5.9e-10 39.6 0.1 1.9 1 1 0 1 1 1 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.9 CRK32545.1 - 3.3e-09 36.9 10.2 3.3e-09 36.9 10.2 2.8 3 0 0 3 3 3 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.11 CRK32545.1 - 0.0056 16.4 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 Cupin domain Nic96 PF04097.14 CRK32546.1 - 1.4e-69 235.2 0.1 4.8e-50 170.7 0.1 2.1 1 1 1 2 2 2 2 Nup93/Nic96 Nucleoporin_FG PF13634.6 CRK32546.1 - 4.4e-08 33.9 41.4 4.4e-08 33.9 41.4 4.0 2 1 0 3 3 3 1 Nucleoporin FG repeat region UbiA PF01040.18 CRK32548.1 - 8.2e-40 136.7 21.7 1.1e-39 136.3 21.7 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Ribosom_S12_S23 PF00164.25 CRK32549.1 - 3.5e-51 171.6 0.6 4.3e-51 171.3 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 DUF5315 PF17242.2 CRK32550.1 - 1.2e-27 95.5 0.6 2.8e-27 94.3 0.6 1.6 1 0 0 1 1 1 1 Disordered region of unknown function (DUF5315) Atg8 PF02991.16 CRK32551.1 - 1.9e-50 169.4 0.2 3.3e-50 168.6 0.2 1.4 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like JAB PF01398.21 CRK32551.1 - 6.1e-30 103.6 0.0 1.1e-29 102.8 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease APG12 PF04110.13 CRK32551.1 - 9.1e-06 26.0 0.1 3.1e-05 24.3 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin-like autophagy protein Apg12 ADK PF00406.22 CRK32552.1 - 5.9e-55 185.5 0.0 6.9e-55 185.3 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CRK32552.1 - 2.7e-19 69.9 0.3 6.3e-19 68.8 0.1 1.6 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 CRK32552.1 - 2.5e-17 62.5 0.0 6.3e-17 61.3 0.0 1.7 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_18 PF13238.6 CRK32552.1 - 0.014 16.0 0.0 0.024 15.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain HOOK PF05622.12 CRK32553.1 - 5.9e-06 24.7 23.1 5.9e-06 24.7 23.1 4.5 2 1 2 4 4 4 2 HOOK protein SlyX PF04102.12 CRK32553.1 - 0.67 10.6 0.1 0.67 10.6 0.1 7.9 7 3 2 10 10 10 0 SlyX PI_PP_I PF18363.1 CRK32553.1 - 1.7 8.9 5.2 15 5.8 0.1 4.1 3 1 1 4 4 4 0 Phosphoinositide phosphatase insertion domain Fez1 PF06818.15 CRK32553.1 - 2.1 8.7 63.5 0.98 9.8 9.3 4.4 3 1 0 4 4 4 0 Fez1 GAS PF13851.6 CRK32553.1 - 4 6.8 68.5 0.5 9.7 16.4 5.8 4 2 1 5 5 5 0 Growth-arrest specific micro-tubule binding ANAPC4_WD40 PF12894.7 CRK32557.1 - 0.00023 21.4 0.1 0.05 13.9 0.0 3.0 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CRK32557.1 - 0.0033 18.2 5.0 0.09 13.7 0.0 4.7 5 0 0 5 5 5 1 WD domain, G-beta repeat Atg8 PF02991.16 CRK32558.1 - 8.5e-41 138.4 0.5 1.6e-40 137.4 0.5 1.4 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like PPTA PF01239.22 CRK32558.1 - 8.9e-37 123.8 9.1 3.5e-10 39.3 1.5 5.4 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat Mito_carr PF00153.27 CRK32558.1 - 2.5e-27 94.6 0.0 3.2e-18 65.4 0.0 2.4 2 0 0 2 2 2 2 Mitochondrial carrier protein SNARE PF05739.19 CRK32558.1 - 1.1e-09 38.1 1.4 2.4e-09 37.1 1.4 1.6 1 0 0 1 1 1 1 SNARE domain APG12 PF04110.13 CRK32558.1 - 0.01 16.2 0.0 0.025 15.0 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-like autophagy protein Apg12 Limkain-b1 PF11608.8 CRK32558.1 - 0.11 12.5 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Limkain b1 Coprogen_oxidas PF01218.18 CRK32562.1 - 6e-139 461.8 0.4 9.2e-139 461.2 0.1 1.4 2 0 0 2 2 2 1 Coproporphyrinogen III oxidase SWIM PF04434.17 CRK32562.1 - 0.015 15.0 3.5 1.2 8.9 0.1 2.4 2 0 0 2 2 2 0 SWIM zinc finger MitMem_reg PF13012.6 CRK32566.1 - 1e-36 125.8 0.0 2.3e-36 124.6 0.0 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 CRK32566.1 - 2.4e-29 101.7 0.0 4.8e-29 100.7 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease tRNA_bind_2 PF13725.6 CRK32566.1 - 0.028 14.1 3.3 0.043 13.5 3.3 1.2 1 0 0 1 1 1 0 Possible tRNA binding domain ADK PF00406.22 CRK32568.1 - 3.7e-59 199.2 0.0 4.9e-59 198.8 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CRK32568.1 - 2.7e-23 82.9 0.3 5.6e-23 81.9 0.1 1.6 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 CRK32568.1 - 3.5e-17 62.1 0.0 8.2e-17 60.9 0.0 1.6 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_18 PF13238.6 CRK32568.1 - 4.9e-07 30.4 0.0 8.3e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CRK32568.1 - 3.6e-05 23.9 0.0 6.8e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain HOOK PF05622.12 CRK32570.1 - 7.8e-06 24.3 84.8 0.0078 14.4 54.3 5.1 3 1 1 4 4 4 3 HOOK protein KELK PF15796.5 CRK32570.1 - 0.013 15.9 5.1 0.013 15.9 5.1 8.1 6 2 2 8 8 8 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF2570 PF10828.8 CRK32570.1 - 0.016 15.0 2.2 0.016 15.0 2.2 5.9 5 2 1 7 7 7 0 Protein of unknown function (DUF2570) PI_PP_I PF18363.1 CRK32570.1 - 1.7 8.8 5.1 17 5.7 0.1 4.1 3 1 1 4 4 4 0 Phosphoinositide phosphatase insertion domain Inhibitor_I9 PF05922.16 CRK32572.1 - 0.00047 20.8 0.0 0.00053 20.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I9 ANAPC4_WD40 PF12894.7 CRK32575.1 - 0.00036 20.8 0.1 0.051 13.9 0.0 2.9 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CRK32575.1 - 0.0054 17.5 5.0 0.098 13.6 0.0 4.6 5 0 0 5 5 5 1 WD domain, G-beta repeat His_Phos_2 PF00328.22 CRK32575.1 - 0.19 11.0 0.0 6.2 6.1 0.0 2.3 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 2) PPTA PF01239.22 CRK32578.1 - 7.2e-40 133.6 9.7 1.4e-10 40.5 1.5 5.3 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat Sporozoite_P67 PF05642.11 CRK32578.1 - 3.6 5.6 9.5 4.9 5.1 9.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Mito_carr PF00153.27 CRK32579.1 - 4e-82 270.3 8.4 1.1e-24 86.2 0.2 4.3 4 0 0 4 4 4 4 Mitochondrial carrier protein EF-hand_7 PF13499.6 CRK32579.1 - 1.2e-21 76.9 5.0 5.1e-11 42.9 0.4 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CRK32579.1 - 2.4e-20 70.5 8.6 2.2e-05 23.7 1.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 CRK32579.1 - 2e-17 61.5 10.5 0.00013 21.6 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CRK32579.1 - 8.4e-16 56.7 9.4 5.1e-05 22.6 0.0 3.7 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 CRK32579.1 - 5.2e-09 35.8 6.2 0.0018 18.1 0.2 3.4 1 1 2 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CRK32579.1 - 4e-08 33.6 0.0 0.0015 18.8 0.0 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Limkain-b1 PF11608.8 CRK32579.1 - 0.094 12.8 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 Limkain b1 Serine_protease PF18405.1 CRK32579.1 - 0.12 11.6 6.2 0.78 8.8 0.1 3.6 4 1 0 4 4 4 0 Gammaproteobacterial serine protease EF-hand_10 PF14788.6 CRK32579.1 - 0.13 12.2 0.4 25 4.8 0.1 2.8 2 1 1 3 3 3 0 EF hand EF-hand_4 PF12763.7 CRK32579.1 - 0.27 11.2 2.5 27 4.8 0.0 3.4 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand Las1 PF04031.13 CRK32580.1 - 0.067 13.3 0.7 1.8 8.7 0.0 2.1 1 1 0 2 2 2 0 Las1-like EF-hand_7 PF13499.6 CRK32581.1 - 4.4e-24 84.7 3.7 4.6e-12 46.2 0.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CRK32581.1 - 5.7e-24 81.8 5.7 9.4e-06 24.8 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 CRK32581.1 - 2.4e-20 70.7 8.4 1.4e-05 24.6 0.1 4.2 3 1 1 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CRK32581.1 - 5.6e-19 66.7 6.9 6.2e-06 25.5 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 CRK32581.1 - 1.2e-11 44.2 6.2 0.00016 21.5 0.3 3.4 1 1 2 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CRK32581.1 - 3.2e-10 40.3 0.0 9.1e-05 22.8 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 CRK32581.1 - 0.00072 19.4 0.5 2.3 8.2 0.1 3.1 2 1 1 3 3 3 2 EF hand EF-hand_4 PF12763.7 CRK32581.1 - 0.00097 19.1 3.1 3 7.8 0.0 3.3 1 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand DUF5580 PF17743.1 CRK32581.1 - 0.14 10.7 0.0 0.53 8.7 0.0 1.7 1 1 1 2 2 2 0 Family of unknown function (DUF5580) Dockerin_1 PF00404.18 CRK32581.1 - 0.21 11.8 1.6 5.4 7.3 0.0 2.5 3 0 0 3 3 3 0 Dockerin type I domain Cyclin_N PF00134.23 CRK32582.1 - 2.5e-10 40.2 1.0 4.1e-10 39.5 0.2 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 CRK32582.1 - 0.0041 17.5 0.4 0.013 15.9 0.4 1.8 1 0 0 1 1 1 1 Cyclin C-terminal domain Hydrolase_4 PF12146.8 CRK32583.1 - 7.3e-14 51.6 0.0 2.2e-13 50.1 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CRK32583.1 - 1e-11 45.9 20.8 1e-11 45.9 20.8 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CRK32583.1 - 1.1e-11 44.9 0.1 1e-09 38.4 0.5 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Thioesterase PF00975.20 CRK32583.1 - 0.027 14.6 0.3 0.047 13.8 0.3 1.3 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_5 PF12695.7 CRK32583.1 - 0.15 11.8 0.0 1.2 8.8 0.0 2.2 3 0 0 3 3 3 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CRK32584.1 - 1.2e-14 54.2 0.0 3.3e-14 52.7 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CRK32584.1 - 4.2e-13 49.5 0.1 3.8e-11 43.1 0.3 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CRK32584.1 - 8.7e-13 49.4 14.2 8.7e-13 49.4 14.2 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Thioesterase PF00975.20 CRK32584.1 - 0.02 15.0 0.2 0.039 14.1 0.2 1.4 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_5 PF12695.7 CRK32584.1 - 0.12 12.1 0.0 1.2 8.9 0.0 2.3 3 0 0 3 3 3 0 Alpha/beta hydrolase family DLH PF01738.18 CRK32584.1 - 0.13 11.8 0.0 1.9 8.0 0.0 2.5 2 1 0 2 2 2 0 Dienelactone hydrolase family DUF4452 PF14618.6 CRK32585.1 - 5.6e-82 273.7 12.0 6.5e-82 273.5 12.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) Retinal PF15449.6 CRK32585.1 - 0.083 10.7 9.9 0.11 10.3 9.9 1.1 1 0 0 1 1 1 0 Retinal protein ATP_bind_3 PF01171.20 CRK32586.1 - 2.8e-74 248.8 0.3 4.3e-25 88.5 0.0 4.4 4 0 0 4 4 4 4 PP-loop family AMP-binding_C PF13193.6 CRK32586.1 - 0.0007 20.5 0.4 4.3 8.4 0.0 3.3 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Peptidase_U49 PF10463.9 CRK32586.1 - 0.036 13.8 0.0 18 5.0 0.0 3.3 3 0 0 3 3 3 0 Peptidase U49 Mito_carr PF00153.27 CRK32587.1 - 2.7e-45 152.2 6.0 3.1e-19 68.7 0.1 4.1 3 1 1 4 4 4 4 Mitochondrial carrier protein Serine_protease PF18405.1 CRK32587.1 - 0.0025 17.0 1.1 0.031 13.4 0.1 2.2 2 0 0 2 2 2 1 Gammaproteobacterial serine protease YtxH PF12732.7 CRK32587.1 - 0.85 10.2 3.5 1.2 9.7 0.1 2.4 2 0 0 2 2 2 0 YtxH-like protein DUF3337 PF11816.8 CRK32588.1 - 6.6e-55 185.6 0.0 1.7e-54 184.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 CRK32588.1 - 3.5e-19 68.8 10.9 0.00034 21.4 0.2 6.6 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.8 CRK32588.1 - 0.059 12.0 1.1 1 8.0 0.1 2.3 2 0 0 2 2 2 0 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 CRK32588.1 - 0.11 12.8 0.8 1.3 9.4 0.0 3.1 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain DEAD PF00270.29 CRK32591.1 - 2.5e-45 154.4 0.0 4.5e-45 153.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CRK32591.1 - 1.1e-23 83.7 0.0 5.1e-23 81.5 0.0 2.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CRK32591.1 - 3.3e-18 65.7 0.7 7.2e-18 64.6 0.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 CRK32591.1 - 8.9e-05 22.6 0.3 0.00042 20.4 0.0 2.3 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit Nop14 PF04147.12 CRK32591.1 - 0.051 11.8 10.9 0.067 11.4 10.9 1.1 1 0 0 1 1 1 0 Nop14-like family 6PF2K PF01591.18 CRK32592.1 - 3.6e-82 275.0 0.7 4.9e-82 274.5 0.7 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase Asp PF00026.23 CRK32592.1 - 1.2e-34 120.1 0.0 2.3e-34 119.3 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease AAA_33 PF13671.6 CRK32592.1 - 1.3e-06 28.6 0.1 2.8e-06 27.6 0.1 1.5 1 0 0 1 1 1 1 AAA domain Asp_protease_2 PF13650.6 CRK32592.1 - 7.3e-06 26.5 0.3 0.69 10.6 0.0 3.9 4 0 0 4 4 4 2 Aspartyl protease His_Phos_1 PF00300.22 CRK32592.1 - 0.00013 21.7 0.0 0.00026 20.7 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) KTI12 PF08433.10 CRK32592.1 - 0.00067 19.2 0.0 0.001 18.6 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 gag-asp_proteas PF13975.6 CRK32592.1 - 0.02 15.4 0.6 14 6.3 0.0 3.9 4 0 0 4 4 4 0 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 CRK32592.1 - 0.042 13.6 0.8 1.6 8.5 0.0 3.1 3 1 0 3 3 3 0 Xylanase inhibitor C-terminal DUF829 PF05705.14 CRK32594.1 - 6.2e-33 114.7 0.0 7.9e-33 114.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) TruB_C_2 PF16198.5 CRK32594.1 - 0.019 15.1 0.0 1.8 8.8 0.0 2.8 3 0 0 3 3 3 0 tRNA pseudouridylate synthase B C-terminal domain KH_1 PF00013.29 CRK32595.1 - 1e-46 156.6 15.4 6.6e-17 61.1 2.8 3.5 3 0 0 3 3 3 3 KH domain Methyltransf_23 PF13489.6 CRK32595.1 - 4.1e-14 52.8 0.0 7.4e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain KH_2 PF07650.17 CRK32595.1 - 6.4e-11 41.9 3.4 0.013 15.3 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 CRK32595.1 - 1.2e-08 34.7 5.3 0.11 12.4 0.1 3.3 3 0 0 3 3 3 3 KH domain Methyltransf_11 PF08241.12 CRK32595.1 - 2.9e-06 27.8 0.0 8.2e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK32595.1 - 3.2e-06 27.8 0.0 8.2e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK32595.1 - 0.016 16.0 0.0 0.043 14.6 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain MOEP19 PF16005.5 CRK32595.1 - 0.021 14.8 0.0 3.1 7.9 0.0 3.0 3 0 0 3 3 3 0 KH-like RNA-binding domain Methyltransf_31 PF13847.6 CRK32595.1 - 0.061 13.1 0.0 0.16 11.7 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain KH_5 PF13184.6 CRK32595.1 - 0.088 12.9 2.7 8.3 6.6 0.1 3.4 3 0 0 3 3 3 0 NusA-like KH domain ERGIC_N PF13850.6 CRK32596.1 - 0.0044 17.3 0.1 0.015 15.6 0.1 1.9 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Baculo_PEP_C PF04513.12 CRK32596.1 - 0.0081 16.2 9.6 1.6 8.8 0.9 4.4 4 1 1 5 5 5 3 Baculovirus polyhedron envelope protein, PEP, C terminus ATP-cone PF03477.16 CRK32596.1 - 0.16 12.6 0.0 0.78 10.3 0.0 2.3 1 1 0 1 1 1 0 ATP cone domain Trp_syntA PF00290.20 CRK32597.1 - 5.8e-57 192.5 0.0 6.6e-57 192.3 0.0 1.0 1 0 0 1 1 1 1 Tryptophan synthase alpha chain Ribosomal_L28 PF00830.19 CRK32598.1 - 2.2e-17 63.0 1.0 3.2e-17 62.4 1.0 1.3 1 0 0 1 1 1 1 Ribosomal L28 family Aminotran_1_2 PF00155.21 CRK32601.1 - 0.0018 17.5 0.0 0.0025 17.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cutinase PF01083.22 CRK32602.1 - 8.7e-39 133.3 0.0 1.1e-38 132.9 0.0 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 CRK32602.1 - 0.00031 20.4 0.0 0.00045 19.8 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_2 PF02230.16 CRK32602.1 - 0.016 15.0 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 CRK32602.1 - 0.033 14.8 0.2 0.043 14.4 0.2 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family VirJ PF06057.11 CRK32602.1 - 0.034 14.0 0.0 0.047 13.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) DUF572 PF04502.13 CRK32604.1 - 7.4 6.1 14.7 1.4 8.5 10.9 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF572) SAPS PF04499.15 CRK32604.1 - 8.7 5.0 9.4 15 4.3 9.4 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Peptidase_S10 PF00450.22 CRK32605.1 - 4.9e-57 194.2 0.0 1.8e-56 192.4 0.0 1.7 1 1 0 1 1 1 1 Serine carboxypeptidase Glyco_hydro_3_C PF01915.22 CRK32606.1 - 1.3e-43 149.4 0.0 3e-43 148.2 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 CRK32606.1 - 1.9e-41 142.5 0.0 3.2e-41 141.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 CRK32606.1 - 2.9e-23 81.7 0.0 5.3e-23 80.9 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Lipase_3 PF01764.25 CRK32607.1 - 4.6e-35 120.6 0.0 7e-35 120.0 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Lipase3_N PF03893.16 CRK32607.1 - 5.2e-06 26.4 0.4 1.2e-05 25.3 0.1 1.8 2 0 0 2 2 2 1 Lipase 3 N-terminal region Abhydrolase_8 PF06259.12 CRK32607.1 - 0.0066 16.1 0.1 0.014 15.0 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase Hydrolase_4 PF12146.8 CRK32607.1 - 0.044 13.0 0.0 0.073 12.3 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 LRR_6 PF13516.6 CRK32608.1 - 9.2e-05 22.2 0.7 15 6.0 0.0 5.6 7 0 0 7 7 7 3 Leucine Rich repeat LRR_4 PF12799.7 CRK32608.1 - 0.0014 19.0 5.0 3.3 8.3 0.0 6.0 5 3 3 8 8 8 2 Leucine Rich repeats (2 copies) CDC45 PF02724.14 CRK32608.1 - 6 5.0 7.6 8.6 4.5 7.6 1.1 1 0 0 1 1 1 0 CDC45-like protein SNF2_N PF00176.23 CRK32609.1 - 4.2e-49 167.1 1.3 4.7e-48 163.7 0.3 2.7 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CRK32609.1 - 4.5e-17 62.4 0.0 1.2e-16 61.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CRK32609.1 - 3.4e-08 33.7 0.6 1e-07 32.1 0.1 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 CRK32609.1 - 0.00011 22.0 10.8 0.00011 22.0 10.8 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CRK32609.1 - 0.00059 20.1 11.0 0.00059 20.1 11.0 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 CRK32609.1 - 0.00096 19.0 10.6 0.00096 19.0 10.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) ERCC3_RAD25_C PF16203.5 CRK32609.1 - 0.0018 17.5 0.0 0.0032 16.7 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_34 PF13872.6 CRK32609.1 - 0.0053 15.7 0.2 0.015 14.2 0.0 1.8 2 0 0 2 2 2 1 P-loop containing NTP hydrolase pore-1 zf-RING_UBOX PF13445.6 CRK32609.1 - 0.0071 16.4 5.4 0.0071 16.4 5.4 2.3 2 0 0 2 2 2 1 RING-type zinc-finger Zn_Tnp_IS91 PF14319.6 CRK32609.1 - 0.018 15.1 12.5 0.29 11.2 1.8 2.5 2 0 0 2 2 2 0 Transposase zinc-binding domain zf_UBZ PF18439.1 CRK32609.1 - 1.5 8.5 6.3 0.99 9.1 1.4 2.7 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger FlhC PF05280.11 CRK32609.1 - 8 6.1 10.0 12 5.6 1.1 2.8 2 1 1 3 3 3 0 Flagellar transcriptional activator (FlhC) Mcm10 PF09332.11 CRK32611.1 - 0.25 10.7 1.4 0.31 10.4 1.4 1.1 1 0 0 1 1 1 0 Mcm10 replication factor Taxilin PF09728.9 CRK32612.1 - 1e-06 28.2 4.1 1.4e-06 27.7 4.1 1.2 1 0 0 1 1 1 1 Myosin-like coiled-coil protein DUF4810 PF16068.5 CRK32612.1 - 0.00044 20.8 0.4 0.0015 19.0 0.4 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4810) NOA36 PF06524.12 CRK32612.1 - 1.6 8.0 7.6 2.2 7.5 7.6 1.2 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 CRK32612.1 - 5.7 4.9 6.8 6.9 4.6 6.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi M16C_assoc PF08367.11 CRK32613.1 - 1.1e-23 83.6 0.0 1.4e-23 83.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase M16C associated Orn_DAP_Arg_deC PF00278.22 CRK32613.1 - 5e-20 71.6 0.0 1.1e-19 70.5 0.0 1.6 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Orn_Arg_deC_N PF02784.16 CRK32613.1 - 2.4e-12 46.7 0.0 4e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Exo_endo_phos PF03372.23 CRK32614.1 - 1.4e-10 41.1 3.8 7.2e-10 38.8 0.1 2.9 3 0 0 3 3 3 1 Endonuclease/Exonuclease/phosphatase family BBS2_Mid PF14783.6 CRK32614.1 - 0.11 12.5 0.5 0.52 10.4 0.0 2.4 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region WD40 PF00400.32 CRK32614.1 - 0.43 11.5 2.9 3.2 8.8 0.1 3.7 5 0 0 5 5 5 0 WD domain, G-beta repeat HMGL-like PF00682.19 CRK32615.1 - 2e-79 266.9 0.8 3e-79 266.3 0.8 1.3 1 0 0 1 1 1 1 HMGL-like Trp_syntA PF00290.20 CRK32615.1 - 0.063 12.1 0.0 8.9 5.1 0.0 2.5 2 0 0 2 2 2 0 Tryptophan synthase alpha chain CTD_bind PF04818.13 CRK32617.1 - 2.2e-12 47.6 0.0 2.8e-11 44.1 0.0 2.4 3 0 0 3 3 3 1 RNA polymerase II-binding domain. B56 PF01603.20 CRK32618.1 - 2.9e-193 642.5 5.3 3.4e-193 642.3 5.3 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 CRK32618.1 - 0.0007 19.5 2.0 0.28 11.1 0.0 2.4 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal SBF2 PF12335.8 CRK32618.1 - 0.11 12.2 0.1 0.29 10.7 0.1 1.7 1 0 0 1 1 1 0 Myotubularin protein Tau95_N PF17682.1 CRK32619.1 - 2.8e-34 118.1 0.0 5.2e-34 117.2 0.0 1.5 1 0 0 1 1 1 1 Tau95 Triple barrel domain Tau95 PF09734.9 CRK32619.1 - 3.5e-32 112.1 0.0 8.2e-32 110.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain RNA_pol_3_Rpc31 PF11705.8 CRK32619.1 - 0.0035 17.6 10.6 0.0035 17.6 10.6 2.6 2 0 0 2 2 2 1 DNA-directed RNA polymerase III subunit Rpc31 AF-4 PF05110.13 CRK32619.1 - 0.7 7.9 2.9 1.1 7.3 2.9 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein bPH_6 PF10756.9 CRK32619.1 - 1.5 9.0 3.6 10 6.3 0.2 3.4 4 0 0 4 4 4 0 Bacterial PH domain DHHC PF01529.20 CRK32620.1 - 7.7e-21 74.6 6.7 9.9e-21 74.3 6.7 1.1 1 0 0 1 1 1 1 DHHC palmitoyltransferase FtsX PF02687.21 CRK32620.1 - 8.3 7.0 8.0 37 4.9 8.0 1.9 1 1 0 1 1 1 0 FtsX-like permease family zf-C2H2_4 PF13894.6 CRK32621.1 - 1.4e-09 38.0 12.8 0.12 13.2 0.5 5.5 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2 PF00096.26 CRK32621.1 - 1e-07 32.0 11.5 0.5 10.9 0.0 5.4 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_8 PF15909.5 CRK32621.1 - 9.7e-05 22.6 5.5 0.0022 18.3 0.8 2.4 2 0 0 2 2 2 2 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 CRK32621.1 - 0.0004 20.3 8.8 0.36 10.9 0.6 4.6 5 0 0 5 5 4 2 C2H2-type zinc finger zf-met PF12874.7 CRK32621.1 - 0.0042 17.4 0.3 55 4.3 0.0 4.5 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_aberr PF17017.5 CRK32621.1 - 0.019 15.1 0.7 0.93 9.6 0.0 2.5 2 0 0 2 2 2 0 Aberrant zinc-finger zf-C2H2_jaz PF12171.8 CRK32621.1 - 0.038 14.3 1.0 8.8 6.8 0.3 4.1 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-LYAR PF08790.11 CRK32621.1 - 0.12 12.3 1.1 0.45 10.5 0.0 2.5 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zinc_ribbon_4 PF13717.6 CRK32621.1 - 0.15 12.0 7.2 8.8 6.3 0.0 4.1 4 0 0 4 4 4 0 zinc-ribbon domain zf-Di19 PF05605.12 CRK32621.1 - 0.21 11.9 13.0 0.36 11.2 0.2 3.5 2 2 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 CRK32621.1 - 0.22 12.0 16.3 3.7 8.1 0.1 5.1 5 0 0 5 5 5 0 Zinc-finger double domain Zn-ribbon_8 PF09723.10 CRK32621.1 - 0.3 11.2 7.0 1.3 9.2 0.3 3.6 2 2 1 3 3 3 0 Zinc ribbon domain zf-C2H2_2 PF12756.7 CRK32621.1 - 0.38 11.1 10.8 13 6.1 0.1 4.4 2 2 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_3rep PF18868.1 CRK32621.1 - 0.54 10.9 3.5 1.1 10.0 1.2 2.4 2 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zinc_ribbon_5 PF13719.6 CRK32621.1 - 1.1 9.1 10.3 4.9 7.0 1.6 3.9 3 1 0 3 3 3 0 zinc-ribbon domain zf-C2H2_9 PF16293.5 CRK32621.1 - 1.3 9.0 7.3 20 5.1 0.1 4.0 4 1 0 4 4 4 0 C2H2 type zinc-finger (1 copy) MT PF12777.7 CRK32623.1 - 6.6e-09 35.2 0.1 6.6e-09 35.2 0.1 1.0 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor ZapB PF06005.12 CRK32623.1 - 0.0032 17.9 1.2 0.0066 16.9 1.2 1.5 1 0 0 1 1 1 1 Cell division protein ZapB Tektin PF03148.14 CRK32623.1 - 0.014 14.1 0.4 0.018 13.8 0.4 1.1 1 0 0 1 1 1 0 Tektin family XhlA PF10779.9 CRK32623.1 - 0.082 13.1 0.4 0.15 12.3 0.4 1.4 1 0 0 1 1 1 0 Haemolysin XhlA FliH PF02108.16 CRK32624.1 - 0.063 13.3 0.0 0.075 13.1 0.0 1.1 1 0 0 1 1 1 0 Flagellar assembly protein FliH P22_AR_C PF10548.9 CRK32624.1 - 0.07 13.3 0.1 0.14 12.3 0.0 1.6 2 0 0 2 2 2 0 P22AR C-terminal domain RIBIOP_C PF04950.12 CRK32626.1 - 3.6e-61 207.1 0.0 4e-61 207.0 0.0 1.0 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal PfkB PF00294.24 CRK32627.1 - 2.6e-36 125.5 0.4 2.9e-36 125.3 0.4 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 CRK32627.1 - 0.00071 19.0 0.0 0.00088 18.7 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase NAD_binding_5 PF07994.12 CRK32627.1 - 0.088 12.2 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase Peptidase_S10 PF00450.22 CRK32628.1 - 4.5e-38 131.7 0.0 6.2e-38 131.3 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase Vps5 PF09325.10 CRK32628.1 - 0.0019 17.8 0.0 0.0025 17.4 0.0 1.1 1 0 0 1 1 1 1 Vps5 C terminal like dCMP_cyt_deam_1 PF00383.23 CRK32629.1 - 5.2e-08 32.7 0.0 5.5e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CRK32629.1 - 1.8e-07 31.0 0.0 2.6e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 CRK32629.1 - 0.00047 20.2 0.0 0.00075 19.6 0.0 1.4 1 0 0 1 1 1 1 Bd3614-like deaminase 6PGD PF00393.19 CRK32630.1 - 4.6e-48 164.1 0.0 5.1e-48 163.9 0.0 1.0 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain DUF401 PF04165.12 CRK32630.1 - 0.21 10.9 0.0 0.27 10.5 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF401) SAM_2 PF07647.17 CRK32632.1 - 1.9e-06 27.9 0.1 3.2e-06 27.1 0.1 1.5 1 1 0 1 1 1 1 SAM domain (Sterile alpha motif) Umbravirus_LDM PF04817.12 CRK32635.1 - 0.007 15.8 6.1 0.01 15.2 6.1 1.3 1 0 0 1 1 1 1 Umbravirus long distance movement (LDM) family PMT_4TMC PF16192.5 CRK32636.1 - 4e-47 160.4 15.3 4.4e-47 160.3 15.3 1.0 1 0 0 1 1 1 1 C-terminal four TMM region of protein-O-mannosyltransferase DUF3007 PF11460.8 CRK32636.1 - 0.18 12.0 3.3 0.16 12.2 1.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3007) DUF5317 PF17248.2 CRK32636.1 - 0.25 11.3 4.8 0.43 10.6 4.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5317) DUF1600 PF07667.11 CRK32636.1 - 7.8 6.7 13.6 0.95 9.7 7.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1600) Mlh1_C PF16413.5 CRK32637.1 - 9.7e-77 258.0 0.0 1.5e-76 257.3 0.0 1.3 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 CRK32637.1 - 6.8e-34 116.1 0.2 1.4e-33 115.0 0.1 1.6 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 CRK32637.1 - 2.5e-11 43.5 0.0 5.3e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CRK32637.1 - 6.2e-06 26.7 0.0 1.6e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_4 PF08448.10 CRK32639.1 - 0.09 13.0 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 PAS fold PAS_4 PF08448.10 CRK32640.1 - 0.06 13.6 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 PAS fold Metallophos PF00149.28 CRK32641.1 - 0.00051 20.6 0.0 0.00057 20.4 0.0 1.0 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase p450 PF00067.22 CRK32642.1 - 7.3e-28 97.5 0.0 8.5e-28 97.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1353 PF07087.11 CRK32645.1 - 0.14 11.9 0.0 0.28 10.9 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1353) Oxysterol_BP PF01237.18 CRK32655.1 - 2.5e-48 164.8 0.0 5.4e-46 157.1 0.0 2.2 1 1 0 1 1 1 1 Oxysterol-binding protein MAM33 PF02330.16 CRK32657.1 - 4.1e-64 216.4 4.0 1.2e-63 214.9 4.0 1.6 1 1 0 1 1 1 1 Mitochondrial glycoprotein Glyco_hydro_43 PF04616.14 CRK32660.1 - 1.5e-65 221.4 2.5 1.9e-65 221.0 2.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 CRK32660.1 - 3.9e-20 72.4 0.0 8.2e-20 71.4 0.0 1.5 2 0 0 2 2 2 1 Beta xylosidase C-terminal Concanavalin A-like domain DUF5597 PF18120.1 CRK32662.1 - 6.2e-27 94.3 0.1 1.1e-26 93.6 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5597) Glyco_hydro_42 PF02449.15 CRK32662.1 - 7.8e-10 38.6 0.0 1.8e-09 37.5 0.0 1.5 1 1 0 1 1 1 1 Beta-galactosidase Glyco_hydro_35 PF01301.19 CRK32662.1 - 7.8e-06 25.7 0.0 0.0022 17.6 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 35 Glyco_hydro_10 PF00331.20 CRK32662.1 - 0.16 11.1 0.0 0.33 10.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 10 Sugar_tr PF00083.24 CRK32664.1 - 5.6e-81 272.7 16.4 6.5e-81 272.5 16.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK32664.1 - 5.6e-24 84.7 25.7 5.6e-24 84.7 25.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Tmemb_9 PF05434.11 CRK32664.1 - 0.21 11.5 0.0 0.46 10.4 0.0 1.5 1 0 0 1 1 1 0 TMEM9 SPX PF03105.19 CRK32668.1 - 1.3e-07 31.9 5.1 1.3e-05 25.3 0.8 2.0 1 1 1 2 2 2 2 SPX domain Carb_kinase PF01256.17 CRK32669.1 - 1.3e-10 41.2 0.6 1.4e-10 41.0 0.6 1.0 1 0 0 1 1 1 1 Carbohydrate kinase HK PF02110.15 CRK32669.1 - 0.039 13.3 0.0 0.048 13.0 0.0 1.1 1 0 0 1 1 1 0 Hydroxyethylthiazole kinase family Cu_amine_oxid PF01179.20 CRK32670.1 - 1.5e-67 228.3 0.0 1.7e-67 228.2 0.0 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain EF_assoc_2 PF08356.12 CRK32671.1 - 5.7e-37 125.6 0.0 7.3e-37 125.2 0.0 1.1 1 0 0 1 1 1 1 EF hand associated EF-hand_6 PF13405.6 CRK32671.1 - 0.0003 20.5 0.4 0.00073 19.3 0.4 1.6 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 CRK32671.1 - 0.00039 19.8 1.0 0.00078 18.8 1.0 1.5 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 CRK32671.1 - 0.0016 17.9 3.2 0.0035 16.8 3.2 1.6 1 0 0 1 1 1 1 EF hand Acetyltransf_3 PF13302.7 CRK32675.1 - 0.00089 19.9 0.0 0.0012 19.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Pkinase_fungal PF17667.1 CRK32677.1 - 3.6e-111 371.9 0.0 4.1e-111 371.6 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 CRK32677.1 - 9e-06 25.2 0.0 2e-05 24.1 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Kdo PF06293.14 CRK32677.1 - 0.012 15.0 0.1 0.046 13.1 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CRK32677.1 - 0.019 14.9 0.5 0.19 11.7 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 CRK32677.1 - 0.2 10.9 0.0 0.63 9.3 0.0 1.7 2 0 0 2 2 2 0 Protein tyrosine kinase APH PF01636.23 CRK32678.1 - 5.4e-07 29.8 0.0 1.4e-06 28.4 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CRK32678.1 - 0.00041 20.0 0.0 0.00079 19.1 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase DHBP_synthase PF00926.19 CRK32680.1 - 6.2e-25 87.8 0.0 6.9e-25 87.7 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase Fungal_trans PF04082.18 CRK32681.1 - 6.8e-09 35.1 0.0 8.3e-09 34.9 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF383 PF04063.14 CRK32684.1 - 0.012 15.3 0.4 0.013 15.2 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF383) DUF2321 PF10083.9 CRK32684.1 - 0.096 12.3 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) UCH PF00443.29 CRK32684.1 - 0.17 11.3 0.2 0.19 11.2 0.2 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase WD40 PF00400.32 CRK32686.1 - 1.6e-06 28.7 0.0 0.49 11.3 0.0 3.5 3 1 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK32686.1 - 0.021 15.1 0.0 1.3 9.3 0.0 2.4 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Pkinase PF00069.25 CRK32689.1 - 1.2e-13 51.1 0.2 1.4e-13 50.9 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK32689.1 - 1.4e-06 27.8 0.1 1.7e-06 27.5 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 CRK32690.1 - 3.9e-36 124.8 0.0 5.3e-36 124.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK32690.1 - 2.8e-23 82.5 0.0 4e-23 82.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CRK32690.1 - 0.00063 19.1 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CRK32690.1 - 0.022 14.1 0.0 0.036 13.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CRK32690.1 - 0.1 12.2 0.0 0.26 10.9 0.0 1.5 2 0 0 2 2 2 0 RIO1 family APH PF01636.23 CRK32690.1 - 0.11 12.4 0.0 0.38 10.6 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Hamartin PF04388.12 CRK32690.1 - 0.14 10.8 8.2 0.15 10.7 8.2 1.0 1 0 0 1 1 1 0 Hamartin protein Pkinase PF00069.25 CRK32691.1 - 3.7e-15 56.0 0.0 5.7e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK32691.1 - 2e-06 27.3 0.0 3.1e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FliT PF05400.13 CRK32691.1 - 0.13 13.1 2.8 1.9 9.4 0.1 3.0 3 0 0 3 3 3 0 Flagellar protein FliT TPR_3 PF07720.12 CRK32692.1 - 0.016 15.2 0.1 0.027 14.5 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 CRK32692.1 - 0.094 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Abhydrolase_1 PF00561.20 CRK32693.1 - 5.6e-07 29.5 0.0 6.7e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold GARS_C PF02843.16 CRK32694.1 - 1.3e-24 86.2 0.9 2.3e-24 85.5 0.9 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain Peripla_BP_4 PF13407.6 CRK32694.1 - 0.0029 17.2 1.2 0.0045 16.6 1.2 1.4 1 1 0 1 1 1 1 Periplasmic binding protein domain Nop PF01798.18 CRK32695.1 - 6e-14 52.1 0.0 1.1e-13 51.3 0.0 1.3 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin EF-hand_1 PF00036.32 CRK32696.1 - 2.8e-27 92.2 6.9 1.8e-06 27.1 0.1 5.2 5 0 0 5 5 5 5 EF hand EF-hand_6 PF13405.6 CRK32696.1 - 9.1e-24 81.3 5.3 5.8e-05 22.7 0.1 5.1 5 0 0 5 5 5 5 EF-hand domain EF-hand_7 PF13499.6 CRK32696.1 - 1.7e-23 82.8 5.3 1.8e-10 41.1 0.0 3.8 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 CRK32696.1 - 2.5e-20 72.1 8.0 1.5e-09 37.6 0.0 5.0 3 2 2 5 5 5 5 EF-hand domain pair EF-hand_5 PF13202.6 CRK32696.1 - 6.4e-18 63.4 3.3 5.6e-05 22.4 0.3 4.5 4 0 0 4 4 4 4 EF hand Tcf25 PF04910.14 CRK32697.1 - 6.2e-15 55.1 0.2 7.8e-15 54.8 0.2 1.1 1 0 0 1 1 1 1 Transcriptional repressor TCF25 HEAT_EZ PF13513.6 CRK32698.1 - 2.7e-10 40.5 3.5 2.3e-05 24.8 0.1 3.1 1 1 2 3 3 3 3 HEAT-like repeat HEAT_2 PF13646.6 CRK32698.1 - 2.3e-08 34.3 0.8 0.0066 16.8 0.1 2.2 1 1 1 2 2 2 2 HEAT repeats MMS19_C PF12460.8 CRK32698.1 - 3.5e-07 29.7 0.0 4.4e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 RNAPII transcription regulator C-terminal Arm PF00514.23 CRK32698.1 - 4.7e-07 29.6 0.2 0.082 13.0 0.0 3.0 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat RIX1 PF08167.12 CRK32698.1 - 1.4e-05 24.9 0.0 3.9e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 rRNA processing/ribosome biogenesis HEAT PF02985.22 CRK32698.1 - 1.5e-05 24.9 1.5 0.15 12.4 0.0 3.3 3 0 0 3 3 3 2 HEAT repeat Vac14_Fab1_bd PF12755.7 CRK32698.1 - 0.00013 22.5 0.0 0.017 15.7 0.0 2.1 1 1 1 2 2 2 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 CRK32698.1 - 0.00015 21.4 0.1 0.00036 20.2 0.1 1.6 1 1 1 2 2 2 1 CLASP N terminal DRIM PF07539.12 CRK32698.1 - 0.00016 20.1 0.0 0.00019 19.9 0.0 1.1 1 0 0 1 1 1 1 Down-regulated in metastasis RTP1_C1 PF10363.9 CRK32698.1 - 0.00043 20.4 0.1 0.00061 19.9 0.1 1.3 1 1 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 1 Adaptin_N PF01602.20 CRK32698.1 - 0.0019 16.8 0.1 0.0024 16.5 0.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region DUF3385 PF11865.8 CRK32698.1 - 0.002 18.1 0.0 0.28 11.1 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3385) Telomere_reg-2 PF10193.9 CRK32698.1 - 0.003 18.0 0.3 0.0051 17.2 0.3 1.4 1 0 0 1 1 1 1 Telomere length regulation protein TFCD_C PF12612.8 CRK32698.1 - 0.016 15.1 0.0 0.023 14.5 0.0 1.4 1 1 0 1 1 1 0 Tubulin folding cofactor D C terminal UNC45-central PF11701.8 CRK32698.1 - 0.02 14.9 0.1 0.03 14.3 0.1 1.3 1 0 0 1 1 1 0 Myosin-binding striated muscle assembly central Dopey_N PF04118.14 CRK32698.1 - 0.028 13.5 0.0 0.03 13.4 0.0 1.1 1 0 0 1 1 1 0 Dopey, N-terminal Cnd1 PF12717.7 CRK32698.1 - 0.065 13.3 0.0 0.13 12.3 0.0 1.5 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_N PF03224.14 CRK32698.1 - 0.075 12.3 0.0 0.08 12.2 0.0 1.1 1 0 0 1 1 1 0 V-ATPase subunit H Iso_dh PF00180.20 CRK32699.1 - 1.4e-26 93.5 0.0 1.5e-26 93.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Clat_adaptor_s PF01217.20 CRK32700.1 - 7e-08 32.5 0.2 8.4e-08 32.2 0.2 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RPM2 PF08579.11 CRK32700.1 - 0.00019 21.8 0.2 0.00026 21.4 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial ribonuclease P subunit (RPM2) KCH PF16944.5 CRK32701.1 - 1.6e-73 247.6 0.2 2.2e-73 247.2 0.2 1.1 1 0 0 1 1 1 1 Fungal potassium channel Lyase_1 PF00206.20 CRK32702.1 - 5.6e-25 88.4 0.0 8.5e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 CRK32702.1 - 8.2e-16 58.3 0.0 2.3e-15 56.9 0.0 1.8 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus Pkinase PF00069.25 CRK32702.1 - 0.0032 16.9 0.0 0.33 10.3 0.0 2.5 3 0 0 3 3 3 2 Protein kinase domain Extensin_2 PF04554.13 CRK32703.1 - 0.17 12.0 6.2 0.36 10.9 6.2 1.5 1 0 0 1 1 1 0 Extensin-like region Lyase_1 PF00206.20 CRK32704.1 - 1.1e-25 90.7 0.1 1.7e-25 90.1 0.1 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 CRK32704.1 - 3e-16 59.7 0.1 9.1e-16 58.2 0.0 1.9 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus Glyoxalase PF00903.25 CRK32705.1 - 1.3e-39 135.4 0.6 3e-19 69.5 0.0 3.3 2 1 1 3 3 3 3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 CRK32705.1 - 2.1e-18 66.6 0.0 1.1e-05 25.7 0.0 4.2 2 2 1 3 3 3 3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 CRK32705.1 - 2.9e-07 31.2 0.0 0.0029 18.4 0.0 3.4 3 1 0 3 3 3 2 Glyoxalase-like domain Glyoxalase_3 PF13468.6 CRK32705.1 - 1.8e-06 28.2 0.0 0.11 12.6 0.1 3.7 3 1 0 3 3 3 2 Glyoxalase-like domain Glyoxalase_2 PF12681.7 CRK32705.1 - 0.00067 19.6 0.3 0.13 12.2 0.0 4.1 3 3 2 5 5 5 1 Glyoxalase-like domain Pfk_N PF18468.1 CRK32705.1 - 0.0007 20.0 0.0 1.3 9.5 0.0 2.7 3 0 0 3 3 3 2 Phosphofructokinase N-terminal domain yeast CppA_N PF14506.6 CRK32705.1 - 0.024 14.7 0.0 0.46 10.6 0.0 2.3 2 0 0 2 2 2 0 CppA N-terminal Glyco_hydro_3_C PF01915.22 CRK32706.1 - 2.4e-51 174.6 0.6 8.2e-50 169.6 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 CRK32706.1 - 9.3e-23 80.1 0.1 2.5e-22 78.8 0.1 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain CARDB PF07705.11 CRK32706.1 - 0.0069 16.6 0.2 0.0069 16.6 0.2 1.9 2 0 0 2 2 2 1 CARDB Mur_ligase_C PF02875.21 CRK32706.1 - 0.035 14.4 0.0 0.22 11.8 0.0 2.1 2 0 0 2 2 2 0 Mur ligase family, glutamate ligase domain Sugar-bind PF04198.13 CRK32706.1 - 0.082 12.0 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Putative sugar-binding domain Imm17 PF15562.6 CRK32707.1 - 0.042 13.7 0.3 0.084 12.8 0.1 1.5 2 0 0 2 2 2 0 Immunity protein 17 CDC45 PF02724.14 CRK32708.1 - 0.22 9.8 8.2 0.25 9.6 8.2 1.0 1 0 0 1 1 1 0 CDC45-like protein Roughex PF06020.11 CRK32708.1 - 0.23 10.5 6.5 0.25 10.4 6.5 1.1 1 0 0 1 1 1 0 Drosophila roughex protein DNA_pol_phi PF04931.13 CRK32708.1 - 1.1 7.3 6.2 1.2 7.2 6.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 CRK32708.1 - 2.5 7.3 6.5 3.1 7.0 6.5 1.2 1 0 0 1 1 1 0 NOA36 protein Apt1 PF10351.9 CRK32708.1 - 5.8 5.7 7.0 5.9 5.6 7.0 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain CCDC106 PF15794.5 CRK32708.1 - 9.2 5.9 7.3 11 5.6 7.3 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 DUF3591 PF12157.8 CRK32709.1 - 5.5e-17 61.6 0.0 7e-17 61.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) DHDPS PF00701.22 CRK32712.1 - 2.3e-18 65.9 0.0 2.5e-18 65.8 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family BTB PF00651.31 CRK32713.1 - 0.00089 19.5 0.0 0.0013 18.9 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain Pkinase PF00069.25 CRK32715.1 - 1.2e-33 116.6 0.1 1.3e-33 116.5 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK32715.1 - 1e-19 70.8 0.1 1.1e-19 70.7 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CRK32715.1 - 6e-07 29.0 0.1 6.9e-07 28.8 0.1 1.0 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CRK32715.1 - 9.4e-06 24.8 0.1 9.5e-06 24.8 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CRK32715.1 - 5.2e-05 23.3 0.0 0.00024 21.1 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 CRK32715.1 - 0.0018 17.9 0.1 0.002 17.7 0.1 1.0 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 CRK32715.1 - 0.0021 17.7 1.1 0.019 14.5 0.8 1.9 1 1 1 2 2 2 1 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.9 CRK32715.1 - 0.0028 17.2 0.0 0.0028 17.2 0.0 1.1 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL WaaY PF06176.11 CRK32715.1 - 0.014 15.0 0.1 0.017 14.7 0.1 1.1 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Seadorna_VP7 PF07387.11 CRK32715.1 - 0.059 12.4 0.0 0.069 12.2 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Sugar_tr PF00083.24 CRK32716.1 - 2.8e-30 105.6 5.9 3.1e-30 105.4 5.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK32716.1 - 1.7e-06 27.2 4.9 1.7e-06 27.2 4.9 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 CRK32716.1 - 0.00026 19.7 1.8 0.00036 19.2 1.8 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_5 PF05631.14 CRK32716.1 - 0.022 13.7 0.9 0.025 13.5 0.9 1.1 1 0 0 1 1 1 0 Sugar-tranasporters, 12 TM WSC PF01822.19 CRK32717.1 - 2.4e-17 62.9 4.5 3.1e-17 62.6 4.5 1.1 1 0 0 1 1 1 1 WSC domain Sugar_tr PF00083.24 CRK32718.1 - 1.9e-67 228.1 18.5 1.9e-67 228.1 18.5 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK32718.1 - 2.3e-36 125.5 73.2 1.7e-25 89.7 29.5 3.3 3 0 0 3 3 3 2 Major Facilitator Superfamily Sulfatase PF00884.23 CRK32718.1 - 1.7e-17 63.8 0.7 3.5e-17 62.8 0.5 1.5 2 0 0 2 2 2 1 Sulfatase Phosphodiest PF01663.22 CRK32718.1 - 4.7e-05 23.1 0.0 0.00017 21.3 0.0 1.9 3 0 0 3 3 3 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 CRK32718.1 - 0.042 12.5 0.2 0.069 11.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) bZIP_1 PF00170.21 CRK32718.1 - 2.3 8.4 6.0 5.3 7.2 6.0 1.6 1 0 0 1 1 1 0 bZIP transcription factor Pex16 PF08610.10 CRK32721.1 - 3.3e-48 164.5 0.1 3.7e-48 164.4 0.1 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) SET PF00856.28 CRK32722.1 - 0.014 15.8 0.1 0.025 15.0 0.1 1.4 1 0 0 1 1 1 0 SET domain TPR_7 PF13176.6 CRK32722.1 - 0.056 13.5 0.2 0.16 12.0 0.1 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-C2H2 PF00096.26 CRK32723.1 - 0.024 15.1 8.9 0.22 12.0 1.2 3.1 3 0 0 3 3 3 0 Zinc finger, C2H2 type GHMP_kinases_N PF00288.26 CRK32724.1 - 1.5e-09 38.0 1.6 2.8e-09 37.1 1.6 1.4 1 0 0 1 1 1 1 GHMP kinases N terminal domain GRAM PF02893.20 CRK32725.1 - 0.0003 20.6 0.0 0.00044 20.1 0.0 1.3 1 0 0 1 1 1 1 GRAM domain Peptidase_M16_C PF05193.21 CRK32727.1 - 2.5e-31 109.1 0.0 3e-31 108.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase M16 inactive domain Clathrin PF00637.20 CRK32731.1 - 3.8e-24 85.2 6.1 8.6e-23 80.8 1.7 2.5 3 0 0 3 3 3 2 Region in Clathrin and VPS MutL_C PF08676.11 CRK32731.1 - 1.8e-09 37.5 0.2 4.2e-08 33.1 0.0 2.5 2 0 0 2 2 2 1 MutL C terminal dimerisation domain TPR_14 PF13428.6 CRK32731.1 - 0.06 14.2 0.2 3.5 8.7 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Curto_V2 PF07325.11 CRK32731.1 - 0.21 11.5 0.5 0.59 10.0 0.5 1.7 1 0 0 1 1 1 0 Curtovirus V2 protein TPR_11 PF13414.6 CRK32731.1 - 1.4 8.6 3.6 0.58 9.9 0.1 2.2 3 0 0 3 3 3 0 TPR repeat CN_hydrolase PF00795.22 CRK32736.1 - 1.4e-14 54.1 0.9 0.0009 18.7 0.0 3.1 2 1 1 3 3 3 3 Carbon-nitrogen hydrolase IPK PF03770.16 CRK32738.1 - 2.5e-53 180.9 0.0 3.9e-53 180.3 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase Pam17 PF08566.10 CRK32738.1 - 0.099 12.5 0.1 0.19 11.6 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 LRR_4 PF12799.7 CRK32742.1 - 2.2e-07 31.1 9.9 0.00053 20.3 2.2 4.4 2 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CRK32742.1 - 0.0027 17.5 13.0 0.043 13.6 2.5 3.1 1 1 3 4 4 4 3 Leucine rich repeat Vpu PF00558.19 CRK32742.1 - 0.91 9.3 4.2 14 5.5 1.0 2.6 2 0 0 2 2 2 0 Vpu protein DUF3507 PF12015.8 CRK32745.1 - 0.00022 21.0 0.0 0.00025 20.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) zf-H2C2_2 PF13465.6 CRK32752.1 - 2.6e-09 37.1 18.4 6.2e-06 26.4 3.1 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 CRK32752.1 - 6.8e-06 26.2 24.2 0.025 15.0 7.4 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CRK32752.1 - 1.9e-05 25.1 21.2 0.23 12.4 6.1 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger ATG16 PF08614.11 CRK32752.1 - 3.4e-05 24.2 0.2 3.4e-05 24.2 0.2 5.2 5 1 1 6 6 4 1 Autophagy protein 16 (ATG16) zf-C2H2_6 PF13912.6 CRK32752.1 - 0.042 13.9 18.8 0.24 11.4 0.1 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger Rad50_zn_hook PF04423.14 CRK32752.1 - 0.07 13.0 2.3 0.47 10.3 0.5 2.6 2 0 0 2 2 2 0 Rad50 zinc hook motif SlyX PF04102.12 CRK32752.1 - 0.072 13.7 4.5 0.37 11.4 4.5 2.3 1 0 0 1 1 1 0 SlyX Zn-ribbon_8 PF09723.10 CRK32752.1 - 1.1 9.4 6.7 0.29 11.3 1.8 2.3 2 0 0 2 2 2 0 Zinc ribbon domain DZR PF12773.7 CRK32752.1 - 1.3 9.1 5.1 3.3 7.8 5.0 1.7 1 1 1 2 2 2 0 Double zinc ribbon zf-Di19 PF05605.12 CRK32752.1 - 2.1 8.7 11.1 1.1 9.6 6.5 2.2 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_9 PF16293.5 CRK32752.1 - 2.8 7.9 4.9 8.5 6.3 0.4 2.8 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) DevR PF01905.16 CRK32753.1 - 0.11 11.6 1.2 0.14 11.2 1.2 1.0 1 0 0 1 1 1 0 CRISPR-associated negative auto-regulator DevR/Csa2 Rhodanese PF00581.20 CRK32754.1 - 0.0003 21.3 0.0 0.00053 20.5 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain adh_short_C2 PF13561.6 CRK32755.1 - 6.1e-33 114.3 1.6 6.5e-33 114.2 1.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRK32755.1 - 1.3e-17 63.9 2.3 1.5e-17 63.7 2.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 CRK32755.1 - 0.058 12.8 0.0 0.066 12.7 0.0 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Kinase-like PF14531.6 CRK32761.1 - 0.12 11.7 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Taxilin PF09728.9 CRK32762.1 - 0.028 13.6 0.8 0.044 12.9 0.2 1.5 2 0 0 2 2 2 0 Myosin-like coiled-coil protein DUF3240 PF11582.8 CRK32762.1 - 0.18 11.9 1.3 0.28 11.3 0.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3240) Fez1 PF06818.15 CRK32762.1 - 0.32 11.4 4.0 0.38 11.2 4.0 1.1 1 0 0 1 1 1 0 Fez1 Spc7 PF08317.11 CRK32762.1 - 0.56 9.0 5.3 0.7 8.7 5.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein FUSC PF04632.12 CRK32762.1 - 7 5.1 15.2 8.9 4.7 15.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family IMS PF00817.20 CRK32763.1 - 2.3e-40 138.0 0.0 3.9e-40 137.3 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family DHHC PF01529.20 CRK32763.1 - 1.9e-25 89.5 3.4 1.9e-25 89.5 3.4 2.3 2 0 0 2 2 2 1 DHHC palmitoyltransferase IMS_C PF11799.8 CRK32763.1 - 7.3e-12 46.0 0.0 1.5e-11 45.0 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain zf_UBZ PF18439.1 CRK32763.1 - 7.2e-11 41.5 2.8 1.9e-10 40.2 2.8 1.8 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger IMS_HHH PF11798.8 CRK32763.1 - 0.0046 17.2 0.0 0.01 16.1 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif DUF3989 PF13150.6 CRK32763.1 - 0.13 12.0 1.2 11 5.8 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3989) DUF485 PF04341.12 CRK32763.1 - 0.82 9.7 6.0 1 9.4 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF485 SET PF00856.28 CRK32764.1 - 8.5e-13 49.0 0.6 8.5e-13 49.0 0.6 2.8 2 1 0 2 2 2 1 SET domain AWS PF17907.1 CRK32764.1 - 6.2e-07 29.3 6.9 6.2e-07 29.3 6.9 2.5 3 0 0 3 3 3 1 AWS domain CRAL_TRIO PF00650.20 CRK32765.1 - 1.3e-07 31.5 0.0 2.3e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain ARPC4 PF05856.12 CRK32766.1 - 5.7e-39 133.4 4.4 9.1e-39 132.7 4.4 1.3 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) UCH PF00443.29 CRK32768.1 - 1.1e-46 159.5 0.0 1.5e-46 159.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CRK32768.1 - 5.3e-12 46.0 5.4 2.1e-10 40.7 5.4 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 CRK32768.1 - 8e-11 41.5 0.1 2.7e-10 39.8 0.0 2.0 3 0 0 3 3 3 1 Ubiquitin family His_Phos_1 PF00300.22 CRK32770.1 - 1.3e-35 122.9 3.9 2.5e-17 63.2 0.6 2.7 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Methyltransf_23 PF13489.6 CRK32771.1 - 1.1e-13 51.4 1.4 1.6e-13 50.8 1.4 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CRK32771.1 - 2.1e-13 50.7 0.2 1.2e-12 48.3 0.1 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK32771.1 - 2.5e-13 50.6 0.0 6.3e-13 49.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK32771.1 - 3e-13 50.3 0.0 1.5e-12 48.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK32771.1 - 1.2e-11 44.7 0.0 2.3e-11 43.7 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 CRK32771.1 - 4.3e-07 29.5 0.0 8e-07 28.6 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 CRK32771.1 - 0.00012 22.1 0.1 0.00031 20.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CRK32771.1 - 0.0064 16.0 0.1 0.015 14.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain TPMT PF05724.11 CRK32771.1 - 0.026 14.2 0.0 0.056 13.1 0.0 1.5 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) CMAS PF02353.20 CRK32771.1 - 0.043 13.1 0.0 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 CRK32771.1 - 0.1 11.5 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Zip PF02535.22 CRK32771.1 - 0.65 9.2 4.4 1 8.5 4.4 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3760 PF12586.8 CRK32773.1 - 0.0036 17.5 0.2 0.013 15.6 0.2 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3760) F-box PF00646.33 CRK32773.1 - 1 9.3 4.1 1.5 8.8 0.3 3.1 3 0 0 3 3 3 0 F-box domain DUF3760 PF12586.8 CRK32774.1 - 0.0026 17.9 0.1 0.0089 16.2 0.1 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3760) GAT PF03127.14 CRK32775.1 - 1.4e-23 83.0 5.6 9.9e-17 61.0 1.3 2.9 2 0 0 2 2 2 2 GAT domain UBX PF00789.20 CRK32775.1 - 1.4e-14 54.1 0.0 6.6e-06 26.2 0.0 2.6 2 0 0 2 2 2 2 UBX domain UBA_4 PF14555.6 CRK32775.1 - 5.6e-11 42.1 0.0 4.7e-10 39.1 0.0 2.3 2 0 0 2 2 2 1 UBA-like domain SUB1_ProdP9 PF18213.1 CRK32775.1 - 0.00045 20.0 0.0 0.58 10.0 0.0 2.5 2 0 0 2 2 2 2 SUB1 protease Prodomain ProdP9 DUF4777 PF16007.5 CRK32775.1 - 0.023 15.0 0.1 4.9 7.5 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4777) SUFU_C PF12470.8 CRK32775.1 - 0.052 13.6 4.7 1.3 9.1 0.4 2.6 2 0 0 2 2 2 0 Suppressor of Fused Gli/Ci N terminal binding domain U1snRNP70_N PF12220.8 CRK32775.1 - 0.053 14.2 12.4 1.2 9.8 1.4 3.9 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF3110 PF11360.8 CRK32775.1 - 0.081 13.1 0.1 17 5.7 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3110) RasGAP_C PF03836.15 CRK32775.1 - 0.35 11.0 2.8 24 5.1 0.0 3.0 3 0 0 3 3 3 0 RasGAP C-terminus Rod_cone_degen PF15201.6 CRK32775.1 - 3.1 8.0 4.8 46 4.2 0.4 3.0 2 0 0 2 2 2 0 Progressive rod-cone degeneration DUF1566 PF07603.11 CRK32775.1 - 5.5 7.4 5.7 14 6.1 0.5 3.3 2 2 0 2 2 2 0 Protein of unknown function (DUF1566) Pan3_PK PF18101.1 CRK32776.1 - 3.1e-64 215.1 0.2 6.7e-64 214.0 0.2 1.6 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 CRK32776.1 - 3.9e-05 23.1 0.1 7.5e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK32776.1 - 0.024 13.9 0.0 0.045 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase zf-CCCH PF00642.24 CRK32776.1 - 0.16 12.0 0.7 0.29 11.1 0.7 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) FoP_duplication PF13865.6 CRK32777.1 - 7.4 7.2 25.1 15 6.2 25.0 1.7 1 1 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Mito_carr PF00153.27 CRK32778.1 - 3.4e-135 440.4 13.3 6.2e-23 80.5 0.1 6.5 6 0 0 6 6 6 6 Mitochondrial carrier protein Pan3_PK PF18101.1 CRK32778.1 - 2.4e-34 118.2 0.0 5.1e-33 114.0 0.1 2.5 2 0 0 2 2 2 1 Pan3 Pseudokinase domain Pkinase PF00069.25 CRK32778.1 - 0.00014 21.3 0.1 0.00024 20.6 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain gp45-slide_C PF09116.10 CRK32778.1 - 0.0036 17.3 0.0 15 5.7 0.0 3.7 3 0 0 3 3 3 1 gp45 sliding clamp, C terminal Dynamitin PF04912.14 CRK32778.1 - 0.074 12.4 5.2 2.9 7.1 0.4 2.2 2 0 0 2 2 2 0 Dynamitin Pkinase_Tyr PF07714.17 CRK32778.1 - 0.11 11.8 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase PX PF00787.24 CRK32779.1 - 6.1e-05 23.0 0.0 0.00016 21.7 0.0 1.7 2 0 0 2 2 2 1 PX domain LSM PF01423.22 CRK32780.1 - 8.1e-20 70.3 0.3 9.8e-20 70.0 0.3 1.1 1 0 0 1 1 1 1 LSM domain FoP_duplication PF13865.6 CRK32780.1 - 2 9.0 21.6 4.1 8.0 21.6 1.5 1 1 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 PX PF00787.24 CRK32781.1 - 4.2e-24 84.7 0.2 1.2e-23 83.2 0.0 1.8 3 0 0 3 3 3 1 PX domain Herpes_U47 PF05467.11 CRK32781.1 - 1.5 6.8 8.1 2.1 6.4 8.1 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein U47 PRP21_like_P PF12230.8 CRK32782.1 - 2.9e-104 347.7 32.6 9e-52 176.1 15.4 3.0 2 1 0 2 2 2 2 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 CRK32782.1 - 2.4e-69 229.2 20.6 3.5e-18 65.3 0.8 4.5 4 0 0 4 4 4 4 Surp module zf_UBZ PF18439.1 CRK32782.1 - 1.2e-05 24.8 3.7 0.069 12.8 0.3 2.5 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger NinF PF05810.12 CRK32782.1 - 0.00054 19.8 0.4 1.9 8.4 0.0 2.8 2 0 0 2 2 2 2 NinF protein AAA_lid_2 PF17863.1 CRK32782.1 - 0.0015 18.3 0.3 5.1 7.0 0.0 3.8 2 0 0 2 2 2 2 AAA lid domain zf-C4H2 PF10146.9 CRK32782.1 - 0.0025 18.2 16.4 0.28 11.5 2.5 2.7 2 0 0 2 2 2 2 Zinc finger-containing protein zf_Rg PF17915.1 CRK32782.1 - 0.0025 17.2 0.1 3.4 7.1 0.0 2.6 2 0 0 2 2 2 2 Reverse gyrase zinc finger GshA PF08886.11 CRK32782.1 - 0.0056 15.3 0.1 2.1 6.8 0.0 2.5 3 0 0 3 3 3 2 Glutamate-cysteine ligase DZR PF12773.7 CRK32782.1 - 0.038 14.0 0.5 13 5.9 0.1 2.4 2 0 0 2 2 2 0 Double zinc ribbon PhnA_Zn_Ribbon PF08274.12 CRK32782.1 - 0.086 12.8 1.0 15 5.7 0.1 2.3 2 0 0 2 2 2 0 PhnA Zinc-Ribbon Sgf11 PF08209.11 CRK32782.1 - 0.087 12.4 1.4 12 5.5 0.1 2.5 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) FAD_binding_5 PF00941.21 CRK32782.1 - 0.11 12.2 0.0 21 4.8 0.0 2.5 2 0 0 2 2 2 0 FAD binding domain in molybdopterin dehydrogenase zf-ACC PF17848.1 CRK32782.1 - 0.15 12.1 0.7 27 5.0 0.1 2.6 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain UPF0547 PF10571.9 CRK32782.1 - 0.24 11.5 4.6 9.9 6.3 0.4 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Tox-ART-HYD1 PF15633.6 CRK32782.1 - 0.27 11.9 0.9 43 4.9 0.1 2.7 2 0 0 2 2 2 0 HYD1 signature containing ADP-ribosyltransferase zf-Di19 PF05605.12 CRK32782.1 - 0.33 11.3 1.5 32 4.9 0.1 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-ribbon_3 PF13248.6 CRK32782.1 - 0.52 9.8 2.0 23 4.6 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_9 PF16293.5 CRK32782.1 - 0.78 9.6 2.3 33 4.4 0.2 2.5 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) YwqJ-deaminase PF14431.6 CRK32782.1 - 1 9.5 5.3 16 5.7 0.6 2.7 2 0 0 2 2 2 0 YwqJ-like deaminase zf_C2H2_10 PF18414.1 CRK32782.1 - 4.3 7.0 5.8 22 4.7 0.5 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger Pkinase_fungal PF17667.1 CRK32783.1 - 4.2e-135 450.7 0.0 5.1e-135 450.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 CRK32783.1 - 2.7e-06 26.9 0.0 4.9e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 CRK32783.1 - 0.012 15.6 0.0 0.028 14.3 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 CRK32783.1 - 0.037 13.4 0.0 0.069 12.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 CRK32784.1 - 1.3e-16 60.7 0.0 2.6e-15 56.5 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK32784.1 - 4.6e-07 29.4 0.0 0.0048 16.2 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CRK32784.1 - 0.016 14.5 0.3 12 5.2 0.1 2.9 3 0 0 3 3 3 0 Kinase-like Kdo PF06293.14 CRK32784.1 - 0.059 12.7 0.0 0.14 11.5 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_hydro_3_C PF01915.22 CRK32785.1 - 3.2e-51 174.2 0.0 5.6e-51 173.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 CRK32785.1 - 1.4e-38 133.0 0.0 2.3e-38 132.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain DUF2052 PF09747.9 CRK32785.1 - 2.3e-25 89.9 15.4 1.3e-12 48.3 9.2 2.3 2 0 0 2 2 2 2 Coiled-coil domain containing protein (DUF2052) Fn3-like PF14310.6 CRK32785.1 - 1e-23 83.2 0.9 2.3e-23 82.1 0.9 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 CRK32785.1 - 8.1e-16 58.1 0.0 2.1e-15 56.8 0.0 1.7 2 0 0 2 2 2 1 PA14 domain Big_2 PF02368.18 CRK32785.1 - 0.031 14.2 2.3 0.17 11.8 0.1 3.0 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 2) Lipase_3 PF01764.25 CRK32786.1 - 2.1e-14 53.6 0.0 1.4e-12 47.7 0.0 2.6 1 1 0 1 1 1 1 Lipase (class 3) SOTI PF17079.5 CRK32786.1 - 0.012 16.0 0.2 0.032 14.6 0.2 1.7 1 0 0 1 1 1 0 Male-specific protein scotti Acetyltransf_1 PF00583.25 CRK32787.1 - 1.8e-10 41.0 0.0 2.3e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CRK32787.1 - 3.1e-08 33.9 0.3 4.4e-08 33.4 0.3 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CRK32787.1 - 1e-06 28.7 0.0 1.3e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AstA PF04958.12 CRK32787.1 - 0.032 12.8 0.0 0.046 12.3 0.0 1.2 1 0 0 1 1 1 0 Arginine N-succinyltransferase beta subunit adh_short_C2 PF13561.6 CRK32788.1 - 5.2e-55 186.6 0.4 6.5e-55 186.2 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRK32788.1 - 1.1e-49 168.6 0.2 1.3e-49 168.3 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CRK32788.1 - 1.4e-12 47.9 0.9 4.1e-12 46.4 0.9 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 CRK32788.1 - 1.3e-06 28.1 0.0 1.7e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 CRK32788.1 - 0.048 12.8 0.1 0.076 12.1 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain ADH_N PF08240.12 CRK32789.1 - 3.4e-28 97.7 0.5 3.4e-28 97.7 0.5 2.2 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CRK32789.1 - 2.2e-17 63.3 0.8 4.3e-17 62.3 0.8 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 CRK32789.1 - 1.6e-08 34.3 0.8 0.0024 17.4 0.2 2.6 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus 2-Hacid_dh_C PF02826.19 CRK32789.1 - 0.0029 17.0 0.1 0.0079 15.6 0.1 1.7 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 CRK32789.1 - 0.0038 16.5 3.7 0.0038 16.5 3.7 1.9 1 1 1 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 CRK32789.1 - 0.0047 16.8 0.8 0.0088 15.9 0.8 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain YdfZ PF14001.6 CRK32789.1 - 0.0069 16.8 0.2 0.49 10.8 0.0 2.9 2 1 0 2 2 2 1 YdfZ protein UDPG_MGDP_dh_N PF03721.14 CRK32789.1 - 0.012 15.1 2.2 0.016 14.8 0.4 2.0 2 1 1 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF1272 PF06906.11 CRK32789.1 - 0.072 13.2 0.5 12 6.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) HI0933_like PF03486.14 CRK32789.1 - 0.081 11.6 1.2 0.12 11.0 1.2 1.2 1 0 0 1 1 1 0 HI0933-like protein TrkA_N PF02254.18 CRK32789.1 - 0.11 12.7 0.7 0.44 10.8 0.1 2.1 2 0 0 2 2 2 0 TrkA-N domain Aldo_ket_red PF00248.21 CRK32790.1 - 1.1e-64 218.5 0.2 5.1e-37 127.7 0.0 3.0 1 1 2 3 3 3 3 Aldo/keto reductase family YflT PF11181.8 CRK32790.1 - 0.002 18.6 0.2 5.6 7.5 0.0 3.1 3 2 0 3 3 3 2 Heat induced stress protein YflT BMC PF00936.19 CRK32790.1 - 0.067 13.2 1.2 16 5.6 0.0 3.0 3 1 0 3 3 3 0 BMC domain DUF1213 PF06740.12 CRK32791.1 - 2.4 8.8 7.5 37 5.0 0.7 3.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1213) Sec2p PF06428.11 CRK32793.1 - 3e-28 97.6 19.7 3e-28 97.6 19.7 2.4 2 1 0 2 2 2 1 GDP/GTP exchange factor Sec2p DUF5401 PF17380.2 CRK32793.1 - 0.00019 19.7 11.4 0.00031 19.0 11.4 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5401) AAA_15 PF13175.6 CRK32793.1 - 0.1 12.3 5.2 0.15 11.8 5.2 1.1 1 0 0 1 1 1 0 AAA ATPase domain DUF3439 PF11921.8 CRK32793.1 - 0.11 12.5 1.1 0.22 11.5 1.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF5339 PF17274.2 CRK32793.1 - 0.22 12.4 16.6 1.1 10.1 7.5 3.3 2 1 1 3 3 3 0 Family of unknown function (DUF5339) Calici_MSP PF05752.11 CRK32793.1 - 0.41 10.5 3.4 1 9.2 3.4 1.6 1 0 0 1 1 1 0 Calicivirus minor structural protein DUF3584 PF12128.8 CRK32793.1 - 1.7 6.1 22.9 2.3 5.6 22.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) CENP-Q PF13094.6 CRK32793.1 - 3 8.0 24.8 0.066 13.4 5.6 3.2 2 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit KASH_CCD PF14662.6 CRK32793.1 - 3.6 7.4 28.8 2.5 7.9 26.3 1.6 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Med9 PF07544.13 CRK32793.1 - 4.7 7.4 16.9 3.3 7.9 0.1 3.2 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 FliD_C PF07195.12 CRK32793.1 - 4.8 6.5 11.7 7.8 5.8 7.9 2.1 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Fib_alpha PF08702.10 CRK32793.1 - 8.8 6.5 20.5 9.3 6.4 7.3 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family PMT PF02366.18 CRK32794.1 - 5.2e-77 258.7 19.5 5.2e-77 258.7 19.5 2.3 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 CRK32794.1 - 3.8e-67 225.8 15.7 3.8e-67 225.8 15.7 2.9 3 0 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 CRK32794.1 - 9.1e-47 159.3 0.6 1.8e-46 158.3 0.1 1.8 2 0 0 2 2 2 1 MIR domain Mucin_bdg PF03272.13 CRK32794.1 - 0.026 14.5 0.1 0.2 11.7 0.0 2.4 2 0 0 2 2 2 0 Putative mucin or carbohydrate-binding module DUF4239 PF14023.6 CRK32794.1 - 5 6.8 7.6 10 5.8 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4239) Bot1p PF12298.8 CRK32795.1 - 4.3e-48 163.7 1.5 4.3e-48 163.7 1.5 2.2 2 0 0 2 2 2 1 Eukaryotic mitochondrial regulator protein Response_reg PF00072.24 CRK32795.1 - 8e-21 74.3 0.0 1.4e-14 54.2 0.0 2.4 2 0 0 2 2 2 2 Response regulator receiver domain TnsD PF15978.5 CRK32795.1 - 0.14 11.1 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 Tn7-like transposition protein D Ribosomal_60s PF00428.19 CRK32795.1 - 0.93 10.1 10.6 1.2 9.7 8.5 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein MARVEL PF01284.23 CRK32796.1 - 1.9e-06 28.0 19.1 7.4e-06 26.1 19.1 1.8 1 1 0 1 1 1 1 Membrane-associating domain VIT1 PF01988.19 CRK32796.1 - 0.06 13.2 5.9 0.074 12.9 5.9 1.2 1 0 0 1 1 1 0 VIT family DUF1294 PF06961.13 CRK32796.1 - 0.24 11.7 0.1 0.24 11.7 0.1 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1294) TMEM192 PF14802.6 CRK32796.1 - 0.35 9.9 3.2 0.24 10.5 0.4 1.8 1 1 1 2 2 2 0 TMEM192 family Pkinase PF00069.25 CRK32797.1 - 3e-19 69.4 0.0 4.6e-19 68.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK32797.1 - 1.1e-13 51.1 0.0 1.9e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CRK32797.1 - 2.9e-05 23.5 0.0 4.7e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CRK32797.1 - 0.0066 16.4 0.3 0.17 11.8 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 CRK32797.1 - 0.069 12.5 0.0 0.22 10.8 0.0 1.8 1 1 0 1 1 1 0 Kinase-like ACD PF16671.5 CRK32798.1 - 0.076 11.3 0.0 0.11 10.8 0.0 1.2 1 0 0 1 1 1 0 Actin cross-linking domain BAR PF03114.18 CRK32800.1 - 1.2e-12 48.0 0.4 2.5e-12 47.0 0.4 1.5 1 1 0 1 1 1 1 BAR domain SH3_1 PF00018.28 CRK32800.1 - 2.3e-12 46.3 0.1 5.2e-12 45.2 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CRK32800.1 - 1.3e-08 34.5 0.0 2.5e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CRK32800.1 - 7.4e-07 28.8 0.0 1.3e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Laminin_II PF06009.12 CRK32800.1 - 0.013 15.5 1.5 1.4 8.9 0.4 2.5 3 0 0 3 3 3 0 Laminin Domain II Caskin-Pro-rich PF16907.5 CRK32800.1 - 0.03 14.9 5.3 0.05 14.1 3.8 2.2 2 0 0 2 2 2 0 Proline rich region of Caskin proteins Med3 PF11593.8 CRK32800.1 - 6.3 5.9 10.0 14 4.8 10.0 1.5 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF2439 PF10382.9 CRK32801.1 - 3e-25 88.3 0.1 6.5e-25 87.3 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) dCMP_cyt_deam_1 PF00383.23 CRK32801.1 - 7.3e-20 70.7 0.0 6.6e-19 67.7 0.0 2.6 2 1 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CRK32801.1 - 4.4e-17 62.1 0.9 5.1e-08 32.8 0.1 3.4 4 0 0 4 4 4 2 MafB19-like deaminase Zn_clus PF00172.18 CRK32801.1 - 0.82 9.8 9.4 1.6 8.9 9.4 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Xan_ur_permease PF00860.20 CRK32803.1 - 2.5e-28 98.9 25.2 5.7e-27 94.4 22.5 2.8 2 1 0 2 2 2 1 Permease family Sulfate_transp PF00916.20 CRK32803.1 - 0.00058 18.7 15.8 0.00098 18.0 13.8 2.3 1 1 1 2 2 2 1 Sulfate permease family MFS_MOT1 PF16983.5 CRK32803.1 - 1.3 9.5 15.8 0.3 11.5 5.5 3.2 2 1 0 2 2 2 0 Molybdate transporter of MFS superfamily DUF4956 PF16316.5 CRK32803.1 - 4.9 6.8 9.7 0.63 9.7 0.1 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4956) NADH-u_ox-rdase PF10785.9 CRK32804.1 - 2.4e-28 98.6 0.1 5.3e-28 97.5 0.1 1.6 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.7 CRK32804.1 - 1.5e-26 92.2 0.0 2.1e-26 91.7 0.0 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Swi3 PF07962.12 CRK32805.1 - 4e-30 103.6 0.2 5.7e-30 103.1 0.2 1.2 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 BDHCT_assoc PF16204.5 CRK32805.1 - 4.2 7.0 5.4 0.3 10.7 0.2 1.7 2 0 0 2 2 2 0 BDHCT-box associated domain on Bloom syndrome protein bZIP_2 PF07716.15 CRK32806.1 - 1.5e-06 28.2 17.3 3.3e-06 27.1 17.3 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 CRK32806.1 - 0.00015 21.8 15.1 0.0003 20.8 15.1 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 CRK32806.1 - 0.0015 19.0 10.3 0.0015 19.0 10.3 1.8 2 0 0 2 2 2 1 bZIP Maf transcription factor NTP_transf_9 PF04248.12 CRK32807.1 - 4.3e-34 116.3 0.6 5.4e-34 115.9 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF427) Snf7 PF03357.21 CRK32808.1 - 6.2e-08 32.4 54.2 7.2e-05 22.4 22.4 2.4 1 1 1 2 2 2 2 Snf7 Ist1 PF03398.14 CRK32808.1 - 6.1e-06 26.3 15.8 0.0011 18.9 4.6 2.4 2 1 0 2 2 2 2 Regulator of Vps4 activity in the MVB pathway UPF0262 PF06793.12 CRK32808.1 - 0.0011 19.0 5.9 0.23 11.5 0.4 2.3 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0262) DUF3276 PF11680.8 CRK32808.1 - 0.022 14.9 7.3 0.93 9.6 0.7 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3276) BRCA2 PF00634.18 CRK32808.1 - 0.19 11.4 5.5 23 4.8 0.1 3.7 4 0 0 4 4 4 0 BRCA2 repeat DDE_Tnp_1_6 PF13751.6 CRK32808.1 - 0.8 9.9 10.9 3.8 7.8 1.0 2.9 2 1 1 3 3 3 0 Transposase DDE domain DUF1512 PF07431.12 CRK32808.1 - 1.2 8.0 11.3 1.5 7.7 1.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1512) SCVP PF17619.2 CRK32808.1 - 2.3 9.1 12.5 3.6 8.5 0.1 3.6 4 0 0 4 4 4 0 Secreted clade V proteins Dehydratase_MU PF02288.15 CRK32808.1 - 6.7 6.7 8.2 15 5.5 0.3 2.9 3 0 0 3 3 3 0 Dehydratase medium subunit DSHCT PF08148.12 CRK32810.1 - 7.7e-54 181.8 0.2 1.7e-53 180.6 0.2 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.6 CRK32810.1 - 2.5e-24 86.6 0.0 4.5e-24 85.8 0.0 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain Helicase_C PF00271.31 CRK32810.1 - 2.8e-06 27.6 0.0 7.4e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Transket_pyr PF02779.24 CRK32812.1 - 1.3e-45 155.2 0.0 1.8e-45 154.8 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 CRK32812.1 - 4e-35 120.4 0.0 1.1e-34 119.0 0.0 1.8 2 0 0 2 2 2 1 Transketolase, C-terminal domain FtsA PF14450.6 CRK32812.1 - 0.027 14.9 0.0 0.099 13.1 0.0 1.9 2 0 0 2 2 2 0 Cell division protein FtsA Sterol_MT_C PF08498.10 CRK32813.1 - 1.6e-28 98.8 0.2 2.8e-28 98.0 0.2 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 CRK32813.1 - 2.4e-21 76.2 0.0 4.8e-21 75.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK32813.1 - 8.3e-20 71.3 0.0 1.7e-19 70.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK32813.1 - 1.6e-17 63.7 0.0 2.4e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CRK32813.1 - 5.5e-12 45.5 0.1 1.9e-11 43.8 0.0 1.8 3 0 0 3 3 3 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 CRK32813.1 - 3e-11 43.4 0.0 5.9e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CRK32813.1 - 1.4e-10 41.0 0.1 2e-10 40.4 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 CRK32813.1 - 3e-10 40.7 0.0 8.2e-10 39.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 CRK32813.1 - 0.00033 19.3 0.0 0.00045 18.9 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.14 CRK32813.1 - 0.00076 19.1 0.0 0.0013 18.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 CRK32813.1 - 0.00094 19.0 0.0 0.0016 18.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 CRK32813.1 - 0.0035 16.8 0.0 0.0071 15.8 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.10 CRK32813.1 - 0.0044 16.6 0.0 0.0068 16.0 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MetW PF07021.12 CRK32813.1 - 0.0071 16.0 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW TehB PF03848.14 CRK32813.1 - 0.036 13.5 0.0 0.062 12.7 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_2 PF00891.18 CRK32813.1 - 0.046 13.0 0.0 0.073 12.4 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain RrnaAD PF00398.20 CRK32813.1 - 0.049 12.7 0.0 0.074 12.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.6 CRK32813.1 - 0.093 12.7 0.1 0.18 11.8 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain RRM_1 PF00076.22 CRK32814.1 - 5.4e-09 35.7 0.0 9.7e-09 34.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CRK32814.1 - 0.0053 16.7 0.0 0.0098 15.9 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 CRK32814.1 - 0.01 15.7 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif RRM_3 PF08777.11 CRK32814.1 - 0.016 15.2 0.0 0.032 14.3 0.0 1.4 1 0 0 1 1 1 0 RNA binding motif Complex1_LYR PF05347.15 CRK32815.1 - 0.00077 19.5 0.0 0.0013 18.7 0.0 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 CRK32815.1 - 0.053 14.3 0.0 0.063 14.0 0.0 1.2 1 0 0 1 1 1 0 Complex1_LYR-like Complex1_LYR PF05347.15 CRK32816.1 - 0.00061 19.8 0.0 0.00082 19.4 0.0 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) RAC_head PF16717.5 CRK32817.1 - 5.9e-30 104.1 2.5 5.9e-30 104.1 2.5 3.6 3 2 0 3 3 3 1 Ribosome-associated complex head domain DnaJ PF00226.31 CRK32817.1 - 8.9e-18 64.2 1.1 8.9e-18 64.2 1.1 2.4 2 0 0 2 2 2 1 DnaJ domain V_ATPase_I PF01496.19 CRK32817.1 - 0.51 8.2 6.3 0.89 7.4 6.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MSP1a PF11670.8 CRK32818.1 - 0.079 12.2 0.1 0.16 11.3 0.1 1.4 1 0 0 1 1 1 0 Major surface protein 1a (MSP1a) DUF1691 PF07950.11 CRK32819.1 - 8.6e-34 116.5 5.0 1.2e-33 116.0 5.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1691) Fungal_trans PF04082.18 CRK32820.1 - 8.2e-13 48.0 0.7 2.3e-12 46.5 0.3 1.9 1 1 0 2 2 2 1 Fungal specific transcription factor domain Transp_inhibit PF18791.1 CRK32820.1 - 0.02 14.4 0.0 0.039 13.4 0.0 1.5 1 0 0 1 1 1 0 Transport inhibitor response 1 protein domain zf-C2H2_jaz PF12171.8 CRK32821.1 - 7.1e-07 29.4 3.2 1.1e-06 28.7 3.2 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CRK32821.1 - 0.00059 20.1 1.0 0.00097 19.4 1.0 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 CRK32821.1 - 0.036 14.4 0.1 0.052 13.9 0.1 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 CRK32821.1 - 0.054 14.4 0.4 0.1 13.5 0.4 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 CRK32821.1 - 0.056 13.9 0.9 0.097 13.2 0.9 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type K_channel_TID PF07941.11 CRK32821.1 - 0.16 12.5 3.6 0.31 11.5 3.6 1.5 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain F-box-like PF12937.7 CRK32822.1 - 6e-15 54.9 8.0 7.5e-07 28.9 1.0 2.8 2 0 0 2 2 2 2 F-box-like Fungal_trans PF04082.18 CRK32822.1 - 8e-13 48.0 0.9 2.5e-12 46.4 0.9 1.8 1 0 0 1 1 1 1 Fungal specific transcription factor domain F-box PF00646.33 CRK32822.1 - 3.8e-10 39.4 6.9 0.00022 21.0 0.8 2.9 2 0 0 2 2 2 2 F-box domain CAF1A PF12253.8 CRK32822.1 - 0.0018 18.4 3.3 0.55 10.4 0.3 2.8 2 0 0 2 2 2 2 Chromatin assembly factor 1 subunit A Zn_clus PF00172.18 CRK32822.1 - 0.0092 16.1 2.7 0.018 15.2 2.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sensor_TM1 PF13755.6 CRK32822.1 - 0.045 13.5 1.5 5.2 6.9 0.1 2.8 2 0 0 2 2 2 0 Sensor N-terminal transmembrane domain Virulence_RhuM PF13310.6 CRK32822.1 - 0.052 12.8 0.1 12 5.0 0.0 2.4 2 0 0 2 2 2 0 Virulence protein RhuM family Transp_inhibit PF18791.1 CRK32822.1 - 0.073 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Transport inhibitor response 1 protein domain F-box_4 PF15966.5 CRK32822.1 - 0.91 9.4 3.7 25 4.8 0.3 2.8 2 0 0 2 2 2 0 F-box zf-C2H2_jaz PF12171.8 CRK32823.1 - 7.2e-07 29.3 3.2 1.1e-06 28.7 3.2 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CRK32823.1 - 0.00059 20.1 1.0 0.00097 19.4 1.0 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 CRK32823.1 - 0.036 14.4 0.1 0.052 13.9 0.1 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 CRK32823.1 - 0.054 14.4 0.4 0.1 13.5 0.4 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 CRK32823.1 - 0.056 13.9 0.9 0.097 13.2 0.9 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type K_channel_TID PF07941.11 CRK32823.1 - 3 8.4 13.4 1.1 9.8 10.7 1.6 1 1 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain SWIRM PF04433.17 CRK32824.1 - 7.8e-15 55.0 0.1 5.1e-13 49.2 0.0 2.3 2 0 0 2 2 2 2 SWIRM domain GRIP PF01465.20 CRK32825.1 - 2e-29 101.2 1.9 1.9e-13 50.1 0.1 2.8 2 0 0 2 2 2 2 GRIP domain adh_short PF00106.25 CRK32825.1 - 1.2e-20 73.8 0.2 8.7e-20 71.0 0.2 2.7 1 0 0 1 1 1 1 short chain dehydrogenase zinc_ribbon_10 PF10058.9 CRK32825.1 - 5.1e-18 64.5 0.1 9.4e-18 63.7 0.1 1.5 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein adh_short_C2 PF13561.6 CRK32825.1 - 7.4e-12 45.3 0.1 2.9e-11 43.4 0.1 2.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK32825.1 - 9.4e-07 28.9 0.2 9.4e-07 28.9 0.2 5.2 5 1 1 6 6 6 1 KR domain Spc7 PF08317.11 CRK32825.1 - 0.0001 21.3 324.5 0.024 13.5 17.3 15.1 6 4 8 14 14 14 9 Spc7 kinetochore protein DUF3800 PF12686.7 CRK32825.1 - 0.00087 19.9 0.0 1.2e+02 3.4 0.0 8.1 2 2 0 2 2 2 0 Protein of unknown function (DUF3800) CALCOCO1 PF07888.11 CRK32825.1 - 0.0016 17.4 25.2 0.0016 17.4 25.2 11.5 5 4 6 11 11 9 4 Calcium binding and coiled-coil domain (CALCOCO1) like YvrJ PF12841.7 CRK32825.1 - 0.0019 17.7 8.9 0.84 9.2 1.3 4.6 2 0 0 2 2 2 2 YvrJ protein family Phage_GP20 PF06810.11 CRK32825.1 - 0.003 17.4 3.9 0.003 17.4 3.9 21.6 7 4 13 21 21 17 2 Phage minor structural protein GP20 Shikimate_DH PF01488.20 CRK32825.1 - 0.0082 16.2 2.2 0.022 14.8 0.1 3.0 3 0 0 3 3 1 1 Shikimate / quinate 5-dehydrogenase TilS PF09179.11 CRK32825.1 - 0.0097 16.4 0.1 14 6.2 0.0 3.3 2 0 0 2 2 2 0 TilS substrate binding domain ADH_zinc_N PF00107.26 CRK32825.1 - 0.016 15.2 0.1 0.038 14.0 0.1 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Nuc_N PF14448.6 CRK32825.1 - 0.39 10.6 4.9 22 5.0 0.4 3.8 2 0 0 2 2 2 0 Nuclease N terminal GP3_package PF16677.5 CRK32825.1 - 0.43 10.7 4.6 26 5.0 0.4 3.6 2 0 0 2 2 2 0 DNA-packaging protein gp3 HTH_34 PF13601.6 CRK32825.1 - 1.1 9.5 7.6 15 5.9 0.4 4.4 3 0 0 3 3 2 0 Winged helix DNA-binding domain Attractin PF08037.11 CRK32825.1 - 2.8 8.0 5.7 33 4.6 0.6 3.1 2 0 0 2 2 2 0 Attractin family HOOK PF05622.12 CRK32825.1 - 4 5.4 308.6 0.22 9.7 73.2 7.7 3 3 2 6 6 6 0 HOOK protein p450 PF00067.22 CRK32828.1 - 5e-36 124.4 0.0 8e-36 123.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.19 CRK32828.1 - 1.3e-15 57.5 1.5 2.1e-13 50.3 1.5 2.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 CRK32828.1 - 0.0014 18.8 0.3 0.0037 17.4 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 CRK32828.1 - 0.0017 17.3 0.4 0.013 14.4 0.0 2.0 1 1 1 2 2 2 1 Tryptophan halogenase Amino_oxidase PF01593.24 CRK32828.1 - 0.0022 17.4 0.6 0.24 10.6 0.1 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.24 CRK32828.1 - 0.0053 16.4 0.0 0.0087 15.7 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 CRK32828.1 - 0.058 14.0 0.3 0.12 12.9 0.3 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CRK32828.1 - 0.06 12.6 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CRK32828.1 - 0.094 11.8 1.1 0.14 11.2 1.1 1.2 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 CRK32828.1 - 0.2 10.7 0.7 0.64 9.0 0.7 1.9 1 1 0 1 1 1 0 Lycopene cyclase protein Rad9 PF04139.13 CRK32832.1 - 0.07 12.6 0.0 0.086 12.3 0.0 1.1 1 0 0 1 1 1 0 Rad9 DUF4106 PF13388.6 CRK32832.1 - 8.6 5.5 8.3 12 5.0 8.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) RCC1 PF00415.18 CRK32833.1 - 2.7e-29 101.5 23.1 1.2e-09 38.6 0.0 7.8 6 2 2 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CRK32833.1 - 2.5e-18 65.4 25.6 1.5e-05 24.7 1.1 6.6 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat NAD_binding_2 PF03446.15 CRK32834.1 - 0.0061 16.7 0.0 0.0068 16.6 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 CRK32834.1 - 0.0077 16.8 0.1 0.013 16.1 0.1 1.6 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 CRK32834.1 - 0.0095 15.3 0.0 0.0095 15.3 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 CRK32834.1 - 0.16 12.0 0.0 0.19 11.8 0.0 1.3 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Rad9 PF04139.13 CRK32836.1 - 3.6e-32 111.8 0.0 7.2e-32 110.8 0.0 1.5 1 0 0 1 1 1 1 Rad9 PDH PF02153.17 CRK32836.1 - 1.3e-15 57.1 0.2 2.8e-15 56.0 0.2 1.5 1 0 0 1 1 1 1 Prephenate dehydrogenase Mpv17_PMP22 PF04117.12 CRK32838.1 - 4.8e-11 42.7 3.6 2.4e-10 40.5 3.3 2.0 2 0 0 2 2 2 1 Mpv17 / PMP22 family EAP30 PF04157.16 CRK32840.1 - 9e-66 221.5 0.0 1e-65 221.3 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Ribosomal_S9 PF00380.19 CRK32842.1 - 7.6e-34 116.8 0.2 8.7e-34 116.7 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Cys_Met_Meta_PP PF01053.20 CRK32852.1 - 1.3e-31 109.5 1.0 1.5e-31 109.3 1.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 CRK32852.1 - 0.00012 21.6 0.3 0.00015 21.2 0.3 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family TruB_C PF09142.11 CRK32855.1 - 0.035 13.9 0.3 0.074 12.8 0.3 1.5 1 0 0 1 1 1 0 tRNA Pseudouridine synthase II, C terminal AMP-binding PF00501.28 CRK32858.1 - 3.9e-20 71.8 0.2 2.3e-18 66.0 0.1 2.1 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 CRK32858.1 - 6.9e-09 36.6 0.0 1.4e-08 35.6 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Vps35 PF03635.17 CRK32859.1 - 3e-297 988.1 0.0 7.9e-297 986.7 0.0 1.6 1 1 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 RAP1 PF07218.11 CRK32859.1 - 0.48 8.7 2.8 0.69 8.1 2.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) 2OG-FeII_Oxy_2 PF13532.6 CRK32862.1 - 2.2e-13 50.8 0.0 3.4e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 CRK32862.1 - 0.016 15.7 0.0 0.034 14.6 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Zn_clus PF00172.18 CRK32863.1 - 7.8e-09 35.5 10.4 1.4e-08 34.7 10.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 CRK32863.1 - 0.012 14.4 0.1 0.018 13.8 0.1 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain p450 PF00067.22 CRK32864.1 - 5.6e-54 183.6 0.0 7e-54 183.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pectate_lyase PF03211.13 CRK32865.1 - 1.8e-73 246.4 2.6 1.8e-73 246.4 2.6 1.5 2 0 0 2 2 2 1 Pectate lyase AhpC-TSA PF00578.21 CRK32866.1 - 0.002 18.0 0.0 0.0028 17.5 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family DUF2868 PF11067.8 CRK32866.1 - 0.39 10.2 2.5 0.52 9.8 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) Upf2 PF04050.14 CRK32867.1 - 8.2e-34 117.3 1.9 1e-33 117.0 1.9 1.1 1 0 0 1 1 1 1 Up-frameshift suppressor 2 A2M PF00207.22 CRK32867.1 - 0.036 13.9 0.1 0.05 13.5 0.1 1.2 1 0 0 1 1 1 0 Alpha-2-macroglobulin family RseA_C PF03873.13 CRK32867.1 - 0.036 14.3 2.2 0.052 13.8 0.5 2.0 2 1 0 2 2 2 0 Anti sigma-E protein RseA, C-terminal domain 6PF2K PF01591.18 CRK32868.1 - 2e-27 96.0 0.0 2.2e-27 95.8 0.0 1.0 1 0 0 1 1 1 1 6-phosphofructo-2-kinase AAA_33 PF13671.6 CRK32868.1 - 0.15 12.2 0.0 0.16 12.1 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.6 CRK32868.1 - 0.17 12.3 0.0 0.18 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain TTSSLRR PF12468.8 CRK32870.1 - 0.011 15.9 0.1 0.025 14.8 0.1 1.5 1 0 0 1 1 1 0 Type III secretion system leucine rich repeat protein Fn3-like PF14310.6 CRK32870.1 - 0.085 13.0 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Fibronectin type III-like domain Peptidase_M41 PF01434.18 CRK32871.1 - 2e-52 177.9 0.0 2.2e-52 177.7 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M41 Ribonuclease PF00545.20 CRK32872.1 - 8.2e-09 36.1 0.2 2.4e-08 34.6 0.0 1.7 1 1 1 2 2 2 1 ribonuclease DIM PF08194.12 CRK32872.1 - 0.17 12.1 7.1 0.19 12.0 0.9 2.5 2 0 0 2 2 2 0 DIM protein ACC_epsilon PF13822.6 CRK32872.1 - 1.5 9.6 6.1 0.4 11.4 1.3 2.0 1 1 1 2 2 2 0 Acyl-CoA carboxylase epsilon subunit PP2C PF00481.21 CRK32876.1 - 1.7e-51 175.4 0.4 5.2e-50 170.5 0.2 2.3 1 1 1 2 2 2 1 Protein phosphatase 2C Snf7 PF03357.21 CRK32876.1 - 1.6e-20 73.4 25.5 2.9e-15 56.3 12.0 3.1 1 1 2 3 3 3 2 Snf7 CaMBD PF02888.16 CRK32876.1 - 0.069 13.4 1.0 0.18 12.0 1.0 1.7 1 0 0 1 1 1 0 Calmodulin binding domain CCAP PF11105.8 CRK32876.1 - 0.081 12.9 0.4 0.16 11.9 0.4 1.5 1 0 0 1 1 1 0 Arthropod cardioacceleratory peptide 2a Dynamin_N PF00350.23 CRK32877.1 - 1.1e-16 61.4 0.0 2.3e-16 60.3 0.0 1.6 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 CRK32877.1 - 5.3e-10 39.4 0.0 4.3e-09 36.4 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CRK32877.1 - 2.1e-06 27.4 0.6 3.8e-05 23.3 0.6 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IIGP PF05049.13 CRK32877.1 - 0.053 12.6 0.0 0.094 11.8 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) TsaE PF02367.17 CRK32877.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 CRK32877.1 - 0.15 11.8 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Nha1_C PF08619.10 CRK32878.1 - 1.1e-108 364.5 19.3 1.4e-108 364.1 19.3 1.0 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.21 CRK32878.1 - 1.6e-76 257.6 26.1 1.9e-76 257.3 26.1 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.6 CRK32878.1 - 5.4 7.2 9.1 0.2 11.7 0.6 2.8 3 0 0 3 3 3 0 YrhC-like protein PPP4R2 PF09184.11 CRK32879.1 - 7.2 6.1 17.4 8.8 5.8 17.4 1.2 1 0 0 1 1 1 0 PPP4R2 Aconitase PF00330.20 CRK32883.1 - 5.3e-33 114.7 0.0 6.5e-33 114.4 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) DUF3361 PF11841.8 CRK32884.1 - 0.0047 16.9 1.6 0.0066 16.4 0.7 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF3361) DHHC PF01529.20 CRK32885.1 - 0.0048 17.0 0.0 0.0064 16.6 0.0 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase Exo_endo_phos PF03372.23 CRK32887.1 - 5.8e-10 39.1 3.6 3.4e-09 36.6 3.6 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 CRK32887.1 - 0.12 12.3 0.1 0.68 9.8 0.0 2.1 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase Fungal_trans PF04082.18 CRK32888.1 - 9.7e-06 24.8 1.6 4e-05 22.8 1.6 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain UvdE PF03851.14 CRK32890.1 - 1.7e-111 371.9 0.0 2.7e-111 371.3 0.0 1.3 1 0 0 1 1 1 1 UV-endonuclease UvdE Fungal_trans PF04082.18 CRK32891.1 - 5.8e-15 55.0 0.3 9.2e-15 54.4 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ECH_1 PF00378.20 CRK32892.1 - 1.9e-41 142.0 0.0 2.5e-41 141.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CRK32892.1 - 3.6e-26 92.5 0.0 3.3e-24 86.0 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase TOM13 PF08219.11 CRK32892.1 - 0.071 13.1 0.0 0.46 10.5 0.0 2.3 2 0 0 2 2 2 0 Outer membrane protein TOM13 4HBT_2 PF13279.6 CRK32893.1 - 9e-05 23.0 0.1 0.00017 22.1 0.1 1.4 1 1 0 1 1 1 1 Thioesterase-like superfamily PP-binding PF00550.25 CRK32894.1 - 2e-07 31.2 0.0 5.3e-07 29.9 0.0 1.7 2 0 0 2 2 2 1 Phosphopantetheine attachment site DUF3422 PF11902.8 CRK32894.1 - 0.014 14.6 0.0 0.016 14.4 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3422) 6PGD PF00393.19 CRK32895.1 - 4.8e-52 177.1 0.0 5.3e-52 177.0 0.0 1.0 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain bMG3 PF11974.8 CRK32895.1 - 0.018 15.1 0.0 0.024 14.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial alpha-2-macroglobulin MG3 domain Pkinase PF00069.25 CRK32899.1 - 6.2e-43 147.1 0.0 1.8e-40 139.0 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CRK32899.1 - 5.7e-21 75.0 0.0 2.3e-18 66.5 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Ribosomal_L34 PF00468.17 CRK32899.1 - 0.0011 18.9 1.7 6.9 6.7 0.1 3.4 3 0 0 3 3 3 2 Ribosomal protein L34 Kinase-like PF14531.6 CRK32899.1 - 0.011 15.1 0.0 0.024 14.0 0.0 1.4 1 1 0 1 1 1 0 Kinase-like VirE1 PF12189.8 CRK32899.1 - 0.023 14.8 0.5 11 6.2 0.1 2.5 2 0 0 2 2 2 0 Single-strand DNA-binding protein APH PF01636.23 CRK32899.1 - 0.053 13.4 0.0 0.083 12.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 CRK32899.1 - 0.094 11.8 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 CRK32899.1 - 0.13 11.0 0.0 0.25 10.1 0.0 1.3 1 1 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 CRK32899.1 - 0.15 10.9 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain DUF5323 PF17257.2 CRK32899.1 - 1.6 8.6 5.6 16 5.4 0.5 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5323) RabGAP-TBC PF00566.18 CRK32900.1 - 7.9e-34 117.2 0.5 1.4e-33 116.3 0.5 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.6 CRK32900.1 - 3e-08 32.9 0.6 0.0082 16.0 0.2 3.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 CRK32900.1 - 6.5e-06 25.3 2.0 0.07 12.7 0.8 3.8 3 0 0 3 3 3 2 EF hand GRAM PF02893.20 CRK32900.1 - 0.0011 18.8 0.0 0.0024 17.7 0.0 1.5 1 0 0 1 1 1 1 GRAM domain EF-hand_7 PF13499.6 CRK32900.1 - 0.0022 18.4 3.5 2.2 8.8 0.2 3.3 3 1 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 CRK32900.1 - 0.0025 17.3 0.7 0.1 12.1 0.3 3.2 3 0 0 3 3 3 1 EF hand WSC PF01822.19 CRK32901.1 - 2.5e-44 149.4 56.0 5e-13 49.0 9.6 4.2 4 0 0 4 4 4 4 WSC domain EMC1_C PF07774.13 CRK32902.1 - 5.5e-74 248.4 0.0 9.2e-74 247.7 0.0 1.4 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ PF01011.21 CRK32902.1 - 0.0068 16.3 0.3 0.3 11.1 0.1 3.4 3 0 0 3 3 3 1 PQQ enzyme repeat RNA_pol_Rpb2_1 PF04563.15 CRK32906.1 - 7.1e-36 123.6 0.1 9.9e-36 123.2 0.1 1.3 1 1 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 CRK32906.1 - 0.068 12.8 0.4 0.099 12.3 0.4 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 2 Coatomer_WDAD PF04053.14 CRK32907.1 - 8.2e-55 186.6 1.3 9.1e-55 186.5 1.3 1.0 1 0 0 1 1 1 1 Coatomer WD associated region Nop14 PF04147.12 CRK32908.1 - 0.11 10.7 21.0 0.14 10.3 21.0 1.0 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.12 CRK32908.1 - 5 5.6 29.8 7.7 5.0 29.8 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Glyco_hydro_15 PF00723.21 CRK32910.1 - 5e-29 101.4 0.0 5.7e-29 101.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Phage_int_SAM_5 PF13102.6 CRK32911.1 - 0.14 12.5 0.0 0.21 12.0 0.0 1.3 1 0 0 1 1 1 0 Phage integrase SAM-like domain Methyltransf_23 PF13489.6 CRK32912.1 - 2.4e-19 69.8 0.0 4.1e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK32912.1 - 3.3e-11 43.8 0.0 1.1e-10 42.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CRK32912.1 - 8.3e-10 39.2 0.0 1.6e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK32912.1 - 3.7e-08 34.0 0.0 2e-07 31.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK32912.1 - 4.9e-08 32.9 0.0 0.012 15.4 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.18 CRK32912.1 - 0.00023 20.6 0.0 0.002 17.5 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 CRK32912.1 - 0.0025 17.3 0.0 0.0045 16.4 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 CRK32912.1 - 0.021 14.3 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.14 CRK32912.1 - 0.03 13.9 0.0 0.054 13.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_16 PF10294.9 CRK32912.1 - 0.057 13.2 0.0 0.094 12.4 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase GidB PF02527.15 CRK32912.1 - 0.071 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Ligase_CoA PF00549.19 CRK32913.1 - 2e-12 47.2 0.1 2.6e-12 46.8 0.1 1.1 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 CRK32913.1 - 0.00074 19.3 0.0 0.00093 19.0 0.0 1.1 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain NifZ PF04319.13 CRK32913.1 - 0.12 12.2 1.9 0.23 11.3 0.3 2.1 2 0 0 2 2 2 0 NifZ domain PUB_1 PF18486.1 CRK32920.1 - 0.031 14.1 0.3 0.081 12.8 0.2 1.8 1 1 1 2 2 2 0 PNGase/UBA- or UBX-containing domain Ocnus PF05005.15 CRK32920.1 - 0.11 12.6 0.1 0.17 12.0 0.1 1.2 1 0 0 1 1 1 0 Janus/Ocnus family (Ocnus) MAP65_ASE1 PF03999.12 CRK32923.1 - 1.6e-13 50.3 0.0 1.9e-13 50.0 0.0 1.0 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) Spectrin PF00435.21 CRK32923.1 - 0.013 16.0 2.8 0.12 12.9 0.9 2.0 1 1 1 2 2 2 0 Spectrin repeat XhlA PF10779.9 CRK32923.1 - 0.029 14.6 1.5 1.1 9.6 1.3 2.1 2 0 0 2 2 2 0 Haemolysin XhlA Occludin_ELL PF07303.13 CRK32923.1 - 0.042 14.6 0.5 0.24 12.2 0.5 1.9 1 1 0 1 1 1 0 Occludin homology domain 2OG-FeII_Oxy_2 PF13532.6 CRK32923.1 - 0.051 13.8 0.0 0.067 13.4 0.0 1.2 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Zn_clus PF00172.18 CRK32927.1 - 3.4e-09 36.7 11.7 5.2e-09 36.1 11.7 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SH3_1 PF00018.28 CRK32931.1 - 9.3e-17 60.4 0.4 2.3e-16 59.1 0.1 1.9 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 CRK32931.1 - 9.1e-14 50.9 0.1 1.8e-13 50.0 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 CRK32931.1 - 2.2e-13 49.8 0.4 6.1e-13 48.4 0.4 1.8 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.26 CRK32931.1 - 0.038 14.1 0.0 0.089 12.9 0.0 1.6 1 0 0 1 1 1 0 WW domain VTC PF09359.10 CRK32935.1 - 3.8e-37 128.2 0.6 4.1e-37 128.1 0.6 1.0 1 0 0 1 1 1 1 VTC domain Fe-ADH PF00465.19 CRK32936.1 - 1.8e-24 86.2 0.0 2e-24 86.1 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase RNA_pol_L_2 PF13656.6 CRK32936.1 - 0.13 12.0 0.1 0.28 11.0 0.1 1.6 1 1 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain HEAT PF02985.22 CRK32940.1 - 5.4e-08 32.4 1.3 0.13 12.6 0.0 4.1 3 1 1 4 4 4 3 HEAT repeat HEAT_2 PF13646.6 CRK32940.1 - 2.7e-05 24.5 0.1 0.016 15.6 0.0 2.2 2 0 0 2 2 2 2 HEAT repeats Cnd1 PF12717.7 CRK32940.1 - 5.5e-05 23.3 0.0 0.0011 19.0 0.0 2.1 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 CRK32940.1 - 0.04 13.5 0.0 3.1 7.3 0.0 2.2 1 1 1 2 2 2 0 CLASP N terminal NUDIX_5 PF16705.5 CRK32940.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 NUDIX, or N-terminal NPxY motif-rich, region of KRIT Adaptin_N PF01602.20 CRK32940.1 - 0.17 10.4 0.0 0.23 10.0 0.0 1.2 1 0 0 1 1 1 0 Adaptin N terminal region SGT1 PF07093.11 CRK32945.1 - 0.062 11.7 0.1 0.093 11.2 0.1 1.1 1 0 0 1 1 1 0 SGT1 protein Dynactin_p62 PF05502.13 CRK32946.1 - 3.4e-76 257.0 10.7 3.9e-76 256.8 10.7 1.0 1 0 0 1 1 1 1 Dynactin p62 family DUF4519 PF15012.6 CRK32946.1 - 0.45 10.7 1.3 0.65 10.2 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Dynactin_p62 PF05502.13 CRK32947.1 - 4.6e-113 378.5 0.0 5.5e-113 378.3 0.0 1.0 1 0 0 1 1 1 1 Dynactin p62 family Ribosomal_S7e PF01251.18 CRK32948.1 - 1.7e-81 272.4 0.1 2e-81 272.2 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e VapB_antitoxin PF09957.9 CRK32949.1 - 0.19 11.7 0.0 0.41 10.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial antitoxin of type II TA system, VapB DUF4448 PF14610.6 CRK32950.1 - 2.1e-29 102.7 0.0 3e-29 102.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Insulin_TMD PF17870.1 CRK32950.1 - 0.24 11.5 0.7 0.52 10.4 0.7 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment AA_permease PF00324.21 CRK32952.1 - 8.8e-09 34.5 0.4 9.2e-09 34.4 0.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CRK32952.1 - 2.5e-08 33.2 0.3 2.7e-08 33.1 0.3 1.0 1 0 0 1 1 1 1 Amino acid permease ATP1G1_PLM_MAT8 PF02038.16 CRK32952.1 - 0.36 10.3 1.1 3.6 7.1 0.1 2.4 2 1 1 3 3 3 0 ATP1G1/PLM/MAT8 family Myosin_head PF00063.21 CRK32953.1 - 1.4e-62 211.9 0.4 1.5e-62 211.8 0.4 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_22 PF13401.6 CRK32953.1 - 6.4e-05 23.2 0.0 0.0001 22.6 0.0 1.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CRK32953.1 - 0.0038 17.6 0.0 0.0039 17.6 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain Sigma54_activat PF00158.26 CRK32953.1 - 0.014 15.2 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain T2SSE PF00437.20 CRK32953.1 - 0.027 13.6 0.0 0.039 13.0 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.12 CRK32953.1 - 0.034 14.1 0.0 0.053 13.4 0.0 1.3 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 CRK32953.1 - 0.037 14.5 0.1 0.051 14.1 0.1 1.5 1 1 0 1 1 1 0 ABC transporter AAA_10 PF12846.7 CRK32953.1 - 0.041 12.8 0.0 0.042 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain RNA_helicase PF00910.22 CRK32953.1 - 0.045 14.1 0.0 0.068 13.6 0.0 1.4 1 1 0 1 1 1 0 RNA helicase DUF2075 PF09848.9 CRK32953.1 - 0.05 12.8 0.0 0.055 12.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 CRK32953.1 - 0.073 12.5 0.1 8.6 5.8 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein AAA_7 PF12775.7 CRK32953.1 - 0.084 12.4 0.1 0.52 9.8 0.0 2.0 2 1 1 3 3 3 0 P-loop containing dynein motor region CbiA PF01656.23 CRK32953.1 - 0.088 12.9 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.6 CRK32953.1 - 0.09 12.5 0.0 0.094 12.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 CRK32953.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE FAD-oxidase_C PF02913.19 CRK32955.1 - 4.8e-31 108.3 0.0 5.3e-31 108.2 0.0 1.0 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain RPEL PF02755.15 CRK32959.1 - 6.9e-21 73.3 3.9 1.1e-09 37.7 0.1 2.6 2 0 0 2 2 2 2 RPEL repeat DARPP-32 PF05395.12 CRK32959.1 - 0.098 12.9 4.4 0.17 12.1 4.4 1.5 1 1 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 zf-H2C2_5 PF13909.6 CRK32959.1 - 0.33 10.7 1.7 11 5.9 0.2 2.2 2 0 0 2 2 2 0 C2H2-type zinc-finger domain p450 PF00067.22 CRK32960.1 - 2.2e-55 188.2 0.0 3.3e-55 187.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_60s PF00428.19 CRK32960.1 - 0.045 14.3 3.5 0.14 12.8 3.5 1.8 1 0 0 1 1 1 0 60s Acidic ribosomal protein CENP-B_dimeris PF09026.10 CRK32960.1 - 1.9 8.9 6.2 4.5 7.7 6.2 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain adh_short PF00106.25 CRK32961.1 - 0.029 13.8 0.0 0.05 13.1 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Nucleoporin_N PF08801.11 CRK32968.1 - 4.6e-48 164.0 0.0 5e-48 163.9 0.0 1.0 1 0 0 1 1 1 1 Nup133 N terminal like Methyltransf_23 PF13489.6 CRK32970.1 - 5.9e-20 71.8 0.0 8.5e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CRK32970.1 - 5.4e-14 52.6 0.0 1.4e-13 51.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK32970.1 - 1.7e-13 51.1 0.0 4.9e-13 49.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK32970.1 - 6.6e-10 39.6 0.0 5.8e-09 36.6 0.0 2.5 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK32970.1 - 3.2e-08 33.5 0.0 8.1e-07 29.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CRK32970.1 - 5.9e-07 29.1 0.0 5.9e-06 25.8 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 CRK32970.1 - 0.0036 16.9 0.0 0.0063 16.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.9 CRK32970.1 - 0.0059 16.4 0.0 0.0094 15.7 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 CRK32970.1 - 0.021 14.3 0.0 0.033 13.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 CRK32970.1 - 0.034 13.6 0.0 0.15 11.5 0.0 2.0 3 0 0 3 3 3 0 Putative methyltransferase Methyltransf_2 PF00891.18 CRK32970.1 - 0.13 11.5 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Peptidase_M43 PF05572.13 CRK32971.1 - 4.6e-16 59.1 0.3 1.1e-15 57.9 0.0 1.6 2 0 0 2 2 2 1 Pregnancy-associated plasma protein-A Peptidase_M10 PF00413.24 CRK32971.1 - 0.0023 17.8 0.1 0.0028 17.5 0.1 1.2 1 0 0 1 1 1 1 Matrixin Reprolysin_5 PF13688.6 CRK32971.1 - 0.0098 16.1 3.2 0.015 15.4 3.2 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 CRK32971.1 - 0.015 15.0 1.2 0.025 14.2 0.6 1.5 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 CRK32971.1 - 0.016 14.5 0.1 0.028 13.6 0.1 1.3 1 0 0 1 1 1 0 Met-zincin Reprolysin_3 PF13582.6 CRK32971.1 - 0.028 15.0 0.6 0.063 13.8 0.4 1.7 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Citrate_synt PF00285.21 CRK32973.1 - 6.1e-30 104.5 0.0 6.5e-30 104.4 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Hist_deacetyl PF00850.19 CRK32974.1 - 0.24 10.8 0.0 0.38 10.2 0.0 1.3 1 0 0 1 1 1 0 Histone deacetylase domain ANTAR PF03861.14 CRK32975.1 - 0.013 15.4 0.2 0.022 14.6 0.2 1.3 1 0 0 1 1 1 0 ANTAR domain Trimer_CC PF08954.11 CRK32975.1 - 0.1 12.2 0.4 0.14 11.7 0.4 1.2 1 0 0 1 1 1 0 Trimerisation motif MutS_V PF00488.21 CRK32976.1 - 8.8e-50 169.4 0.0 9.8e-50 169.2 0.0 1.0 1 0 0 1 1 1 1 MutS domain V LRR_6 PF13516.6 CRK32977.1 - 3.9e-09 35.8 0.1 0.062 13.4 0.0 4.1 4 0 0 4 4 4 3 Leucine Rich repeat LRR_4 PF12799.7 CRK32977.1 - 0.00013 22.2 0.2 0.053 14.0 0.0 2.6 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CRK32977.1 - 0.0033 17.8 0.3 7.9 7.5 0.1 3.2 3 0 0 3 3 3 2 Leucine Rich Repeat LRR_8 PF13855.6 CRK32977.1 - 0.048 13.4 0.1 16 5.4 0.0 3.3 3 1 1 4 4 3 0 Leucine rich repeat Pectinesterase PF01095.19 CRK32979.1 - 9e-49 165.8 1.7 1.2e-48 165.3 1.7 1.1 1 0 0 1 1 1 1 Pectinesterase GARS_C PF02843.16 CRK32979.1 - 0.073 13.4 0.8 0.82 10.0 0.5 2.7 2 1 0 2 2 2 0 Phosphoribosylglycinamide synthetase, C domain COesterase PF00135.28 CRK32980.1 - 7e-61 206.6 0.0 1.1e-60 206.0 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CRK32980.1 - 3.6e-05 23.7 0.0 0.0018 18.2 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CRK32980.1 - 0.00058 19.4 0.0 0.00095 18.7 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 CRK32980.1 - 0.022 14.4 0.1 0.022 14.4 0.1 1.7 2 0 0 2 2 2 0 Putative esterase Say1_Mug180 PF10340.9 CRK32980.1 - 0.18 10.7 0.0 0.55 9.0 0.0 1.7 2 0 0 2 2 2 0 Steryl acetyl hydrolase MFS_1 PF07690.16 CRK32981.1 - 3.7e-33 114.9 27.2 3.7e-33 114.9 27.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily CYSTM PF12734.7 CRK32981.1 - 1.3 9.4 6.9 3.6 8.0 6.9 1.7 1 0 0 1 1 1 0 Cysteine-rich TM module stress tolerance AA_permease PF00324.21 CRK32982.1 - 2.6e-103 346.2 32.6 3.3e-103 345.9 32.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CRK32982.1 - 1e-22 80.6 36.9 1.2e-22 80.3 36.9 1.1 1 0 0 1 1 1 1 Amino acid permease Ole-e-6 PF09253.10 CRK32982.1 - 0.011 15.6 0.4 0.027 14.4 0.4 1.6 1 0 0 1 1 1 0 Pollen allergen ole e 6 Glyco_hydro_3_C PF01915.22 CRK32983.1 - 1.2e-36 126.6 0.0 2.1e-36 125.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 CRK32983.1 - 1.4e-26 93.6 0.0 2.8e-26 92.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain MFS_1 PF07690.16 CRK32983.1 - 2.1e-11 43.4 52.4 2.8e-09 36.4 52.4 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 CRK32983.1 - 3.1e-08 32.5 16.7 5.2e-08 31.8 16.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Malic_M PF03949.15 CRK32984.1 - 1.4e-84 283.4 0.1 1.8e-84 283.0 0.1 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 CRK32984.1 - 5.6e-65 218.5 0.0 8e-65 218.0 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain DUF5427 PF10310.9 CRK32985.1 - 7.9e-177 588.9 0.1 9.4e-177 588.6 0.1 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5427) Flu_M1_C PF08289.11 CRK32985.1 - 0.057 13.6 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain Ndc1_Nup PF09531.10 CRK32985.1 - 0.66 8.6 1.8 0.9 8.2 1.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FAD_binding_4 PF01565.23 CRK32987.1 - 7.8e-32 109.9 1.2 1.2e-31 109.3 1.2 1.3 1 0 0 1 1 1 1 FAD binding domain Ribosomal_L14 PF00238.19 CRK32987.1 - 2.4e-31 108.3 0.0 3.9e-31 107.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e XLF PF09302.11 CRK32988.1 - 1.7e-50 171.7 0.0 3.8e-50 170.5 0.0 1.6 1 0 0 1 1 1 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component Forkhead PF00250.18 CRK32989.1 - 5.4e-15 55.4 0.0 1.2e-14 54.3 0.0 1.6 1 0 0 1 1 1 1 Forkhead domain Cactin_mid PF10312.9 CRK32990.1 - 2.5e-63 213.4 10.4 3.5e-63 212.9 10.4 1.2 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.9 CRK32990.1 - 8.1e-58 193.8 5.4 1.4e-57 193.0 5.4 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein SF3A2 PF16835.5 CRK32990.1 - 0.0069 16.7 0.0 0.032 14.6 0.0 2.1 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) DUF1087 PF06465.13 CRK32990.1 - 0.024 14.7 3.9 0.033 14.2 0.8 2.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1087) DUF3417 PF11897.8 CRK32990.1 - 0.083 13.4 0.3 0.083 13.4 0.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3417) FAD_binding_7 PF03441.14 CRK32991.1 - 1.9e-82 275.6 0.1 2.9e-82 275.0 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 CRK32991.1 - 3.1e-41 141.1 0.1 4.9e-41 140.5 0.1 1.2 1 0 0 1 1 1 1 DNA photolyase Fungal_trans_2 PF11951.8 CRK32993.1 - 1.7e-64 218.0 0.4 2.9e-64 217.3 0.4 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK32993.1 - 8.3e-08 32.2 6.7 1.8e-07 31.2 6.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MARVEL PF01284.23 CRK32994.1 - 0.0033 17.4 16.2 0.013 15.6 15.7 1.9 1 1 0 1 1 1 1 Membrane-associating domain Pro_isomerase PF00160.21 CRK32995.1 - 4.3e-41 140.8 0.2 5.6e-41 140.5 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RNA_pol_Rpc34 PF05158.12 CRK32996.1 - 1.9e-89 300.4 0.0 2.1e-89 300.2 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit RPA_C PF08784.11 CRK32996.1 - 0.04 14.6 0.0 1.2 9.9 0.0 3.0 3 0 0 3 3 3 0 Replication protein A C terminal Ribosomal_S25 PF03297.15 CRK32996.1 - 0.17 12.1 0.0 0.33 11.2 0.0 1.5 1 0 0 1 1 1 0 S25 ribosomal protein Pro_isomerase PF00160.21 CRK32997.1 - 1.3e-40 139.3 0.2 1.6e-40 138.9 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RNA_pol_Rpc34 PF05158.12 CRK32998.1 - 7.1e-101 337.9 0.0 8.8e-101 337.6 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit RPA_C PF08784.11 CRK32998.1 - 0.048 14.3 0.2 1.3 9.7 0.0 3.2 4 0 0 4 4 4 0 Replication protein A C terminal Ribosomal_S25 PF03297.15 CRK32998.1 - 0.075 13.2 0.1 0.45 10.7 0.0 2.2 2 0 0 2 2 2 0 S25 ribosomal protein Zip PF02535.22 CRK32999.1 - 2.8e-50 171.4 0.1 4.5e-50 170.8 0.1 1.3 1 1 0 1 1 1 1 ZIP Zinc transporter Zip PF02535.22 CRK33000.1 - 1.3e-49 169.2 1.1 2e-49 168.6 1.1 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter PMSR PF01625.21 CRK33001.1 - 1.7e-64 216.7 1.2 2e-64 216.4 1.2 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Bax1-I PF01027.20 CRK33002.1 - 3.4e-33 115.2 10.7 7.5e-33 114.1 10.7 1.5 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 PMSR PF01625.21 CRK33003.1 - 2.2e-64 216.3 1.6 2.6e-64 216.0 1.6 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Bax1-I PF01027.20 CRK33004.1 - 3.7e-33 115.1 10.5 3.7e-33 115.1 10.5 2.0 2 0 0 2 2 2 1 Inhibitor of apoptosis-promoting Bax1 Med25_SD1 PF11235.8 CRK33004.1 - 0.15 12.4 2.6 0.28 11.5 2.6 1.4 1 0 0 1 1 1 0 Mediator complex subunit 25 synapsin 1 Glyco_hydro_45 PF02015.16 CRK33005.1 - 5.2e-88 294.4 16.2 7.3e-88 294.0 16.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 CBM_1 PF00734.18 CRK33005.1 - 2.9e-07 30.3 2.4 2.9e-07 30.3 2.4 2.7 2 0 0 2 2 2 1 Fungal cellulose binding domain cNMPbd_u2 PF16643.5 CRK33006.1 - 8e-34 117.4 14.0 8e-34 117.4 14.0 2.3 2 0 0 2 2 2 1 Unstructured region on cNMP-binding protein cNMP_binding PF00027.29 CRK33006.1 - 3.5e-33 113.5 0.0 1.9e-17 63.1 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain LRR_6 PF13516.6 CRK33006.1 - 1.6e-09 37.0 3.6 0.034 14.2 0.0 5.3 6 0 0 6 6 6 3 Leucine Rich repeat LRR_4 PF12799.7 CRK33006.1 - 5.1e-07 29.9 0.2 0.093 13.2 0.0 3.8 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) F-box PF00646.33 CRK33006.1 - 1e-06 28.4 0.1 1e-06 28.4 0.1 3.3 3 0 0 3 3 3 1 F-box domain LRR_1 PF00560.33 CRK33006.1 - 7e-06 25.9 2.9 4 8.3 0.0 6.0 7 0 0 7 7 7 2 Leucine Rich Repeat F-box-like PF12937.7 CRK33006.1 - 5.4e-05 23.0 0.0 0.00017 21.4 0.0 1.9 1 0 0 1 1 1 1 F-box-like Cupin_3 PF05899.12 CRK33006.1 - 0.026 14.2 0.1 6.2 6.6 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF861) LRR_8 PF13855.6 CRK33006.1 - 0.039 13.7 1.0 5.8 6.8 0.0 3.7 3 2 0 3 3 3 0 Leucine rich repeat Dscam_C PF12355.8 CRK33006.1 - 0.099 13.6 0.3 0.099 13.6 0.3 2.4 3 0 0 3 3 3 0 Down syndrome cell adhesion molecule C terminal Glyco_hydro_6 PF01341.17 CRK33007.1 - 8.4e-101 337.7 0.2 1.1e-100 337.3 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 cNMPbd_u2 PF16643.5 CRK33008.1 - 1.2e-35 123.3 15.0 2.9e-35 122.0 15.0 1.7 1 0 0 1 1 1 1 Unstructured region on cNMP-binding protein cNMP_binding PF00027.29 CRK33008.1 - 2.3e-33 114.1 0.0 1.5e-17 63.4 0.0 2.7 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain F-box PF00646.33 CRK33008.1 - 3.7e-07 29.8 1.4 8.3e-07 28.7 0.1 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 CRK33008.1 - 6e-05 22.9 0.0 0.00014 21.6 0.0 1.7 1 0 0 1 1 1 1 F-box-like Cupin_3 PF05899.12 CRK33008.1 - 0.017 14.8 0.1 5.2 6.8 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF861) DUF4483 PF14825.6 CRK33008.1 - 0.31 10.8 2.0 0.78 9.5 2.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4483) Glyco_hydro_6 PF01341.17 CRK33009.1 - 2.5e-103 346.0 0.1 3.3e-103 345.6 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 adh_short PF00106.25 CRK33010.1 - 6e-34 117.2 0.0 8e-34 116.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK33010.1 - 4.9e-27 95.0 0.0 6.5e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK33010.1 - 0.0015 18.5 0.3 0.0062 16.5 0.2 2.0 2 1 0 2 2 2 1 KR domain Epimerase PF01370.21 CRK33010.1 - 0.0018 17.8 0.0 0.003 17.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DFP PF04127.15 CRK33010.1 - 0.025 14.4 0.0 0.049 13.5 0.0 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein TRI12 PF06609.13 CRK33011.1 - 1.5e-51 175.6 20.1 1.7e-51 175.3 20.1 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 CRK33011.1 - 8.7e-22 77.5 50.3 8.7e-22 77.5 50.3 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily ABM PF03992.16 CRK33012.1 - 0.0021 18.1 0.1 3.8 7.7 0.0 2.8 2 1 0 2 2 2 2 Antibiotic biosynthesis monooxygenase Adeno_E4_34 PF04528.13 CRK33012.1 - 0.15 11.9 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Adenovirus early E4 34 kDa protein conserved region GRDP-like PF07173.12 CRK33014.1 - 2.7e-15 57.3 5.1 1.3e-10 42.1 0.1 3.2 3 2 0 3 3 3 2 Glycine-rich domain-containing protein-like zf-Sec23_Sec24 PF04810.15 CRK33014.1 - 7.2 6.8 6.5 4.8 7.3 2.8 2.3 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Ribosomal_S21e PF01249.18 CRK33016.1 - 5.2e-41 138.6 0.2 5.8e-41 138.5 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Haem_oxygenas_2 PF14518.6 CRK33016.1 - 0.087 12.6 0.0 0.093 12.5 0.0 1.1 1 0 0 1 1 1 0 Iron-containing redox enzyme Slx4 PF09494.10 CRK33017.1 - 4.2e-25 87.5 0.0 9.1e-25 86.4 0.0 1.6 1 0 0 1 1 1 1 Slx4 endonuclease AT_hook PF02178.19 CRK33017.1 - 0.062 13.2 23.7 0.33 11.0 6.0 3.8 3 0 0 3 3 3 0 AT hook motif Cpn60_TCP1 PF00118.24 CRK33021.1 - 2.1e-136 455.4 7.7 1.2e-111 373.8 1.1 2.0 1 1 1 2 2 2 2 TCP-1/cpn60 chaperonin family Pyr_redox_2 PF07992.14 CRK33021.1 - 0.022 14.0 1.1 0.22 10.7 0.9 2.3 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PNTB_4TM PF12769.7 CRK33021.1 - 0.062 13.8 0.0 0.21 12.1 0.0 1.9 2 0 0 2 2 2 0 4TM region of pyridine nucleotide transhydrogenase, mitoch HET PF06985.11 CRK33023.1 - 2.2e-26 92.9 4.1 1e-25 90.8 4.1 2.0 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RlaP PF10127.9 CRK33023.1 - 0.1 12.2 0.1 0.18 11.3 0.1 1.3 1 0 0 1 1 1 0 RNA repair pathway DNA polymerase beta family DUF1744 PF08490.12 CRK33024.1 - 7.3e-155 515.5 0.0 1e-154 515.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 CRK33024.1 - 1.3e-77 261.2 0.9 2e-77 260.6 0.9 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 CRK33024.1 - 3.9e-16 58.8 0.0 6.3e-13 48.2 0.1 2.6 2 1 0 2 2 2 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 CRK33024.1 - 2.1e-10 40.6 0.3 6.1e-10 39.1 0.3 1.7 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 CRK33024.1 - 7.8e-06 26.0 0.1 2.9e-05 24.1 0.1 2.0 1 1 0 1 1 1 1 RNase_H superfamily DUF3767 PF12597.8 CRK33025.1 - 1.8e-32 111.1 0.0 1.8e-32 111.1 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3767) PALP PF00291.25 CRK33025.1 - 0.015 14.7 0.1 0.02 14.3 0.1 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme CCB1 PF12046.8 CRK33025.1 - 0.027 13.8 0.0 0.036 13.4 0.0 1.2 1 0 0 1 1 1 0 Cofactor assembly of complex C subunit B BEX PF04538.12 CRK33025.1 - 0.04 14.5 2.5 0.04 14.5 2.5 1.5 2 0 0 2 2 2 0 Brain expressed X-linked like family Aldose_epim PF01263.20 CRK33028.1 - 1.6e-55 188.5 0.0 2.1e-55 188.2 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Collagen PF01391.18 CRK33030.1 - 6 6.7 47.8 0.15 11.8 37.8 2.7 2 1 1 3 3 3 0 Collagen triple helix repeat (20 copies) VID27 PF08553.10 CRK33034.1 - 9.7e-143 475.5 0.1 2e-133 444.9 0.0 2.2 1 1 1 2 2 2 2 VID27 C-terminal WD40-like domain VID27_N PF17748.1 CRK33034.1 - 1.5e-76 256.1 0.7 1.5e-76 256.1 0.7 2.9 2 1 1 3 3 3 1 VID27 N-terminal region VID27_PH PF17747.1 CRK33034.1 - 5.5e-45 152.1 0.9 2.2e-44 150.2 0.3 2.1 2 0 0 2 2 2 1 VID27 PH-like domain CDC45 PF02724.14 CRK33034.1 - 0.92 7.7 6.0 1.3 7.2 6.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Cpn60_TCP1 PF00118.24 CRK33035.1 - 1.5e-160 535.0 0.1 1.7e-160 534.9 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Herpes_UL6 PF01763.16 CRK33035.1 - 0.12 10.9 0.0 0.17 10.3 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like PDCD2_C PF04194.13 CRK33036.1 - 1.2e-44 152.5 0.1 4.3e-43 147.4 0.0 2.6 2 1 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain CSN8_PSD8_EIF3K PF10075.9 CRK33037.1 - 8e-36 123.2 0.0 1.1e-35 122.8 0.0 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family DNA_ligase_A_N PF04675.14 CRK33038.1 - 2.3e-07 31.3 0.0 3.7e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 DNA ligase N terminus NuDC PF16273.5 CRK33038.1 - 0.029 14.9 3.5 0.046 14.2 3.1 1.6 1 1 0 1 1 1 0 Nuclear distribution C domain DUF3694 PF12473.8 CRK33038.1 - 0.036 14.7 0.1 0.081 13.6 0.1 1.6 2 0 0 2 2 2 0 Kinesin protein DNA_ligase_A_M PF01068.21 CRK33039.1 - 6.6e-49 166.3 0.1 3.7e-46 157.4 0.0 2.1 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_C PF04679.15 CRK33039.1 - 6.5e-18 65.2 0.0 2.7e-17 63.2 0.0 2.0 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 CRK33039.1 - 0.00028 21.2 0.0 0.00086 19.7 0.0 1.8 2 0 0 2 2 2 1 RNA ligase mRNA_cap_enzyme PF01331.19 CRK33039.1 - 0.061 13.1 0.2 4 7.2 0.0 2.2 2 0 0 2 2 2 0 mRNA capping enzyme, catalytic domain Adaptin_N PF01602.20 CRK33040.1 - 9.6e-139 463.3 4.7 1.3e-138 462.8 4.7 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CRK33040.1 - 4.7e-63 212.1 3.0 7.4e-62 208.2 0.4 2.6 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CRK33040.1 - 5.4e-17 62.0 3.8 1.1e-06 28.9 0.1 6.1 2 1 5 7 7 7 5 HEAT repeats HEAT PF02985.22 CRK33040.1 - 6.2e-11 41.6 6.5 0.016 15.4 0.0 6.3 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.6 CRK33040.1 - 2.3e-05 24.8 1.2 0.29 11.7 0.0 5.3 4 1 1 5 5 4 1 HEAT-like repeat UNC45-central PF11701.8 CRK33040.1 - 0.0078 16.2 0.4 0.27 11.2 0.1 2.7 2 0 0 2 2 2 1 Myosin-binding striated muscle assembly central CLASP_N PF12348.8 CRK33040.1 - 0.02 14.5 0.4 1.7 8.1 0.0 3.5 3 1 1 4 4 4 0 CLASP N terminal RTP1_C1 PF10363.9 CRK33040.1 - 0.02 15.0 1.0 1.5 9.0 0.0 4.1 2 2 1 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 CRK33040.1 - 0.023 14.7 1.6 13 6.0 0.0 4.9 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat RIX1 PF08167.12 CRK33040.1 - 0.029 14.1 0.1 6.7 6.4 0.1 3.0 2 1 0 2 2 2 0 rRNA processing/ribosome biogenesis Atx10homo_assoc PF09759.9 CRK33040.1 - 0.05 13.6 0.0 11 6.2 0.0 3.4 2 1 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain BolA PF01722.18 CRK33041.1 - 2.3e-19 69.4 0.1 5.4e-19 68.3 0.1 1.5 1 1 0 1 1 1 1 BolA-like protein NIF3 PF01784.18 CRK33042.1 - 4.2e-62 210.0 0.0 5.3e-62 209.6 0.0 1.1 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) DUF4050 PF13259.6 CRK33043.1 - 1.9e-61 207.6 0.5 1.9e-61 207.6 0.5 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF4050) Fungal_trans_2 PF11951.8 CRK33044.1 - 6e-06 25.3 0.1 1.2e-05 24.4 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Abhydrolase_4 PF08386.10 CRK33045.1 - 2e-18 66.4 0.0 4.4e-18 65.3 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 CRK33045.1 - 6.5e-18 65.3 0.0 4.7e-13 49.4 0.0 2.9 2 1 0 2 2 2 2 alpha/beta hydrolase fold Glyco_hydro_3_C PF01915.22 CRK33046.1 - 1e-47 162.7 0.0 2.1e-47 161.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 CRK33046.1 - 2e-40 139.1 0.0 3.5e-40 138.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain GATA PF00320.27 CRK33047.1 - 0.00016 21.2 7.3 0.022 14.4 2.8 2.7 2 0 0 2 2 2 2 GATA zinc finger PBP PF01161.20 CRK33048.1 - 3.3e-09 37.1 0.0 6.8e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Herpes_pp85 PF04637.12 CRK33048.1 - 0.43 8.9 1.2 0.65 8.3 1.2 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Ribosomal_L4 PF00573.22 CRK33049.1 - 5.5e-62 208.9 0.0 2.8e-44 151.1 0.0 2.2 2 0 0 2 2 2 2 Ribosomal protein L4/L1 family bZIP_1 PF00170.21 CRK33050.1 - 6e-13 48.7 1.5 6e-13 48.7 1.5 2.2 3 0 0 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.15 CRK33050.1 - 1.6e-09 37.7 0.7 5e-09 36.1 0.7 1.9 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 CRK33050.1 - 0.00089 19.7 2.1 0.00089 19.7 2.1 2.4 2 0 0 2 2 2 1 bZIP Maf transcription factor TMEM237 PF15383.6 CRK33050.1 - 0.051 12.7 1.0 0.083 12.0 1.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 237 NAM-associated PF14303.6 CRK33050.1 - 0.87 10.3 14.7 1.7 9.3 14.7 1.5 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain DUF4551 PF15087.6 CRK33050.1 - 4.3 6.1 10.1 5.5 5.7 10.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Rep_fac-A_3 PF08661.11 CRK33051.1 - 5.2e-20 71.8 0.0 5.6e-20 71.6 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 Peptidase_M43 PF05572.13 CRK33052.1 - 1.4e-13 51.0 0.1 2e-13 50.5 0.1 1.2 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 CRK33052.1 - 0.0018 18.5 0.4 0.0025 18.0 0.4 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 CRK33052.1 - 0.0061 17.1 0.0 0.0092 16.5 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 CRK33052.1 - 0.03 13.6 0.1 0.27 10.4 0.1 2.0 2 0 0 2 2 2 0 Met-zincin Reprolysin_2 PF13574.6 CRK33052.1 - 0.034 14.0 0.1 0.048 13.5 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like SAP25 PF15476.6 CRK33052.1 - 0.049 13.3 0.2 0.09 12.4 0.2 1.3 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP25 Reprolysin_4 PF13583.6 CRK33052.1 - 0.11 12.1 0.1 0.16 11.6 0.1 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Glyco_hydro_61 PF03443.14 CRK33053.1 - 2.1e-51 174.8 0.0 2.4e-51 174.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 tRNA_SAD PF07973.14 CRK33054.1 - 2.1e-07 30.9 0.9 5.7e-07 29.5 0.9 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Lipoprotein_2 PF00921.17 CRK33054.1 - 0.03 13.9 0.2 0.051 13.1 0.2 1.3 1 0 0 1 1 1 0 Borrelia lipoprotein tRNA-synt_2c PF01411.19 CRK33054.1 - 0.043 12.3 0.0 0.061 11.8 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class II (A) Cupin_1 PF00190.22 CRK33055.1 - 8.7e-44 148.8 0.0 1.3e-21 76.8 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 CRK33055.1 - 3.7e-26 90.6 1.6 3.6e-13 49.0 0.2 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 CRK33055.1 - 5.3e-09 35.7 0.0 0.00011 21.8 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 CRK33055.1 - 7.8e-08 32.3 0.1 0.00059 19.7 0.0 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain MannoseP_isomer PF01050.18 CRK33055.1 - 0.002 18.0 0.0 0.12 12.3 0.0 2.2 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase ARD PF03079.14 CRK33055.1 - 0.0053 17.0 1.0 0.25 11.5 0.1 2.3 2 0 0 2 2 2 1 ARD/ARD' family 3-HAO PF06052.12 CRK33055.1 - 0.18 11.4 0.0 1.3 8.7 0.0 2.0 2 0 0 2 2 2 0 3-hydroxyanthranilic acid dioxygenase cNMP_binding PF00027.29 CRK33055.1 - 0.2 11.8 0.0 1.9 8.6 0.0 2.3 2 0 0 2 2 2 0 Cyclic nucleotide-binding domain Cupin_7 PF12973.7 CRK33055.1 - 0.34 10.8 1.8 0.94 9.4 0.1 2.6 3 1 0 3 3 3 0 ChrR Cupin-like domain Sulfate_transp PF00916.20 CRK33056.1 - 7e-79 265.3 10.2 1e-78 264.8 10.2 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 CRK33056.1 - 1.5e-09 37.5 0.0 3.1e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 CRK33056.1 - 0.028 14.8 0.0 0.18 12.2 0.0 2.2 2 0 0 2 2 2 0 STAS domain MotB_plug PF13677.6 CRK33056.1 - 0.055 13.1 0.5 0.14 11.8 0.5 1.6 1 0 0 1 1 1 0 Membrane MotB of proton-channel complex MotA/MotB Fungal_trans PF04082.18 CRK33057.1 - 2.9e-17 62.6 0.1 4.2e-17 62.1 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK33057.1 - 0.00069 19.7 8.7 0.0014 18.7 8.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4892 PF16234.5 CRK33057.1 - 0.13 11.8 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4892) ADH_N PF08240.12 CRK33058.1 - 7.9e-29 99.7 0.2 1.5e-28 98.8 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.6 CRK33058.1 - 1.2e-08 34.7 0.2 3.4e-08 33.3 0.2 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N PF00107.26 CRK33058.1 - 1.7e-07 31.2 0.1 3.6e-07 30.2 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 CRK33058.1 - 5.7e-07 29.2 0.0 7.1e-05 22.4 0.0 2.2 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 CRK33058.1 - 0.0013 18.1 0.1 0.0022 17.3 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 CRK33058.1 - 0.004 15.9 0.2 0.0095 14.7 0.2 1.6 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 CRK33058.1 - 0.055 14.0 0.2 0.37 11.4 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CRK33058.1 - 0.088 12.0 0.0 0.23 10.7 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CRK33058.1 - 0.098 12.2 0.1 0.2 11.2 0.1 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CRK33058.1 - 0.13 11.3 0.2 0.27 10.3 0.1 1.4 1 1 0 1 1 1 0 FAD binding domain DAO PF01266.24 CRK33059.1 - 9.8e-33 114.2 3.1 1.5e-32 113.6 3.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_4 PF01565.23 CRK33059.1 - 3.2e-21 75.5 0.3 1.9e-20 73.1 0.3 2.2 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 CRK33059.1 - 3.1e-09 36.8 0.5 6.4e-09 35.8 0.5 1.5 1 0 0 1 1 1 1 Berberine and berberine like Pyr_redox_2 PF07992.14 CRK33059.1 - 0.00019 20.7 1.3 0.034 13.4 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 CRK33059.1 - 0.0015 17.9 1.4 4.5 6.5 0.0 3.3 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 CRK33059.1 - 0.0058 15.8 0.2 0.0058 15.8 0.2 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 CRK33059.1 - 0.0072 16.9 0.3 0.0072 16.9 0.3 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 CRK33059.1 - 0.026 14.8 0.2 0.078 13.2 0.2 1.8 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_9 PF13454.6 CRK33059.1 - 0.039 13.9 0.7 6 6.8 0.1 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 CRK33059.1 - 0.044 14.0 0.1 0.044 14.0 0.1 2.4 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.18 CRK33059.1 - 0.086 13.1 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Trp_halogenase PF04820.14 CRK33059.1 - 0.087 11.7 2.5 1.5 7.6 2.5 2.2 1 1 0 1 1 1 0 Tryptophan halogenase ThiF PF00899.21 CRK33059.1 - 0.12 11.8 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 ThiF family DUF3425 PF11905.8 CRK33061.1 - 8.1e-05 22.6 1.1 0.00034 20.6 1.1 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 CRK33061.1 - 0.013 15.6 0.7 0.013 15.6 0.7 1.7 2 0 0 2 2 2 0 bZIP transcription factor Arrestin_C PF02752.22 CRK33062.1 - 2.1e-10 41.2 0.0 4.5e-09 36.9 0.0 2.3 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CRK33062.1 - 2.4e-10 40.7 0.0 5.9e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 CRK33062.1 - 0.00024 20.9 0.0 0.00046 20.0 0.0 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like CBS PF00571.28 CRK33064.1 - 1.2e-22 80.1 8.3 9.6e-11 42.0 0.2 4.4 4 0 0 4 4 4 3 CBS domain RhoGAP PF00620.27 CRK33064.1 - 4.4e-12 46.1 0.0 1e-11 44.9 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain APH PF01636.23 CRK33065.1 - 1.5e-10 41.4 0.1 4.6e-10 39.8 0.1 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 CRK33065.1 - 0.0022 17.4 0.0 0.021 14.2 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain DUF1679 PF07914.11 CRK33065.1 - 0.013 14.4 0.0 0.12 11.2 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1679) Fructosamin_kin PF03881.14 CRK33065.1 - 0.041 13.1 0.0 0.063 12.5 0.0 1.2 1 0 0 1 1 1 0 Fructosamine kinase Choline_kinase PF01633.20 CRK33065.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Arm PF00514.23 CRK33066.1 - 1.9e-93 304.0 44.1 8.5e-13 47.9 0.2 14.4 14 0 0 14 14 14 12 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 CRK33066.1 - 7.3e-24 83.8 16.7 0.0014 19.1 0.2 9.7 5 2 5 10 10 10 6 HEAT-like repeat HEAT_2 PF13646.6 CRK33066.1 - 1.5e-20 73.3 12.2 0.00038 20.8 0.0 8.1 5 3 2 7 7 7 5 HEAT repeats HEAT PF02985.22 CRK33066.1 - 1.2e-19 68.7 23.4 0.31 11.4 0.4 11.3 12 0 0 12 12 10 7 HEAT repeat Adaptin_N PF01602.20 CRK33066.1 - 8.3e-13 47.7 15.0 7.6e-07 28.1 1.9 3.5 2 1 2 4 4 4 2 Adaptin N terminal region KAP PF05804.12 CRK33066.1 - 4.4e-12 45.0 1.8 8.2e-07 27.6 0.4 2.3 1 1 1 2 2 2 2 Kinesin-associated protein (KAP) Arm_2 PF04826.13 CRK33066.1 - 3.9e-10 39.6 20.2 6.3e-06 25.8 4.9 3.7 3 2 1 4 4 4 2 Armadillo-like V-ATPase_H_N PF03224.14 CRK33066.1 - 1.9e-09 37.3 11.4 0.00078 18.8 4.5 3.9 2 1 2 4 4 4 3 V-ATPase subunit H APH PF01636.23 CRK33066.1 - 2.3e-09 37.5 0.0 1.6e-08 34.8 0.0 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF3361 PF11841.8 CRK33066.1 - 2e-06 27.8 17.5 0.062 13.2 0.3 4.9 3 1 2 5 5 5 2 Domain of unknown function (DUF3361) Cnd1 PF12717.7 CRK33066.1 - 5.9e-05 23.2 14.2 0.14 12.2 0.3 4.8 1 1 3 5 5 5 3 non-SMC mitotic condensation complex subunit 1 DUF5578 PF17741.1 CRK33066.1 - 0.00031 20.3 13.9 0.84 9.0 0.7 6.6 5 3 3 8 8 8 2 Family of unknown function (DUF5578) Vac14_Fab1_bd PF12755.7 CRK33066.1 - 0.0036 17.9 1.6 17 6.1 0.1 4.6 3 2 0 4 4 4 0 Vacuolar 14 Fab1-binding region V-ATPase_H_C PF11698.8 CRK33066.1 - 0.0061 16.7 10.7 36 4.5 0.0 5.8 3 2 5 8 8 8 0 V-ATPase subunit H HEAT_PBS PF03130.16 CRK33066.1 - 0.016 15.8 10.0 51 5.0 0.3 8.0 9 0 0 9 9 9 0 PBS lyase HEAT-like repeat Pkinase PF00069.25 CRK33066.1 - 0.016 14.6 0.0 0.21 10.9 0.0 2.2 2 0 0 2 2 2 0 Protein kinase domain UNC45-central PF11701.8 CRK33066.1 - 0.021 14.8 6.9 8.5 6.3 0.4 4.1 4 0 0 4 4 4 0 Myosin-binding striated muscle assembly central Tti2 PF10521.9 CRK33066.1 - 0.037 13.6 1.6 24 4.4 0.0 3.2 3 0 0 3 3 3 0 Tti2 family Sigma70_r1_1 PF03979.14 CRK33066.1 - 0.082 13.0 4.2 4.5 7.4 0.0 3.1 3 0 0 3 3 2 0 Sigma-70 factor, region 1.1 DUF1679 PF07914.11 CRK33066.1 - 0.11 11.3 0.0 0.44 9.3 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1679) Peptidase_S26 PF10502.9 CRK33067.1 - 3.9e-06 26.7 0.0 0.00018 21.3 0.0 2.3 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.23 CRK33067.1 - 0.00078 19.3 0.0 0.0016 18.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase S24-like IF3_C PF00707.22 CRK33068.1 - 6.3e-06 26.1 0.1 1.3e-05 25.1 0.1 1.5 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.6 CRK33068.1 - 0.0021 17.7 1.3 0.0035 17.0 1.3 1.3 1 0 0 1 1 1 1 Mitochondrial translation initiation factor ACC_epsilon PF13822.6 CRK33068.1 - 0.091 13.5 0.9 0.091 13.5 0.9 3.4 4 0 0 4 4 4 0 Acyl-CoA carboxylase epsilon subunit IF-2B PF01008.17 CRK33069.1 - 1.1e-44 152.7 0.1 3.5e-44 151.1 0.1 1.7 1 1 0 1 1 1 1 Initiation factor 2 subunit family DUF4701 PF15773.5 CRK33069.1 - 3 6.7 14.2 4.5 6.1 13.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4701) PNTB PF02233.16 CRK33072.1 - 1.1e-174 581.7 28.1 1.1e-174 581.7 28.1 2.1 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 CRK33072.1 - 3.3e-74 248.8 0.0 3.3e-74 248.8 0.0 2.3 2 0 0 2 2 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 CRK33072.1 - 2.2e-47 160.7 0.0 8.8e-47 158.8 0.0 2.1 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 CRK33072.1 - 9.6e-31 106.1 3.9 9.6e-31 106.1 3.9 5.2 2 1 2 5 5 5 1 4TM region of pyridine nucleotide transhydrogenase, mitoch 2-Hacid_dh_C PF02826.19 CRK33072.1 - 0.0017 17.8 0.1 0.45 9.8 0.0 2.5 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.26 CRK33072.1 - 0.0026 17.8 2.3 0.0072 16.3 0.0 3.0 3 0 0 3 3 3 1 Zinc-binding dehydrogenase TPP_enzyme_M PF00205.22 CRK33072.1 - 0.0034 17.1 0.7 0.044 13.5 0.7 2.6 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain NAD_binding_8 PF13450.6 CRK33072.1 - 0.019 15.2 0.5 0.13 12.5 0.4 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CRK33072.1 - 0.021 14.1 2.6 0.025 13.8 0.1 2.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_23 PF13489.6 CRK33072.1 - 0.035 13.9 0.0 0.068 13.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 CRK33072.1 - 0.053 13.3 0.0 0.44 10.3 0.0 2.4 3 0 0 3 3 3 0 Methyltransferase domain FAD_binding_2 PF00890.24 CRK33072.1 - 0.33 10.0 3.8 0.6 9.1 1.8 2.1 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.27 CRK33072.1 - 3.3 8.3 6.2 5.5 7.6 0.1 3.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NDUFA12 PF05071.16 CRK33073.1 - 6.8e-30 103.8 0.4 8.3e-30 103.5 0.4 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 PLDc_2 PF13091.6 CRK33074.1 - 4.3e-17 62.3 0.0 2e-07 31.0 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 CRK33074.1 - 1.4e-07 31.4 3.4 0.019 15.2 0.1 3.0 2 1 0 2 2 2 2 Phospholipase D Active site motif Ank_2 PF12796.7 CRK33075.1 - 5.2e-10 39.8 0.2 0.00085 19.9 0.0 3.6 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CRK33075.1 - 5.7e-10 39.5 4.9 0.00052 20.5 0.1 4.1 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 CRK33075.1 - 8.9e-05 22.7 3.0 0.0018 18.6 0.2 3.5 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.30 CRK33075.1 - 0.00041 20.7 7.0 0.018 15.4 0.1 4.5 5 0 0 5 5 5 1 Ankyrin repeat Ank_3 PF13606.6 CRK33075.1 - 0.033 14.7 4.6 0.28 11.9 0.1 4.2 6 0 0 6 6 6 0 Ankyrin repeat Ribosomal_S19e PF01090.19 CRK33075.1 - 0.097 12.4 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein S19e CortBP2 PF09727.9 CRK33077.1 - 0.00081 19.4 1.7 0.0012 18.8 1.7 1.2 1 0 0 1 1 1 1 Cortactin-binding protein-2 DUF4763 PF15960.5 CRK33077.1 - 0.015 14.6 2.1 0.019 14.3 2.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) Pedibin PF08182.11 CRK33077.1 - 0.068 13.0 6.0 0.076 12.8 4.4 1.9 2 0 0 2 2 2 0 Pedibin/Hym-346 family Cutinase PF01083.22 CRK33080.1 - 1.6e-41 142.2 0.0 1.8e-41 142.0 0.0 1.0 1 0 0 1 1 1 1 Cutinase VirJ PF06057.11 CRK33080.1 - 0.01 15.7 0.0 0.016 15.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) MFS_1 PF07690.16 CRK33081.1 - 4.7e-27 94.8 28.0 6.6e-27 94.3 28.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_3_C PF01915.22 CRK33082.1 - 4.7e-58 196.5 0.0 2e-57 194.5 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 CRK33082.1 - 6.4e-57 193.3 0.0 1e-56 192.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 CRK33082.1 - 3.9e-18 65.3 0.3 2.7e-17 62.6 0.1 2.3 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.12 CRK33082.1 - 0.0068 16.2 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 PA14 domain Beta-lactamase PF00144.24 CRK33083.1 - 1.8e-33 116.2 0.0 2.9e-33 115.5 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 CRK33083.1 - 0.15 11.7 0.0 6.2 6.4 0.0 2.3 2 0 0 2 2 2 0 Beta-lactamase enzyme family Sugar_tr PF00083.24 CRK33084.1 - 7e-65 219.6 14.6 1e-64 219.1 14.6 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK33084.1 - 8e-22 77.6 29.6 4.3e-20 71.9 21.7 2.9 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.6 CRK33084.1 - 5.8e-09 35.0 17.2 8.3e-07 27.9 4.1 3.3 2 1 1 3 3 3 2 MFS/sugar transport protein DUF872 PF05915.12 CRK33084.1 - 0.0094 16.1 0.0 0.035 14.3 0.0 2.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF872) MFS_1_like PF12832.7 CRK33084.1 - 0.58 9.0 11.0 0.36 9.6 4.5 2.7 1 1 0 2 2 2 0 MFS_1 like family NAD_binding_4 PF07993.12 CRK33085.1 - 5.9e-05 22.3 0.0 7.8e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 CRK33085.1 - 0.0002 20.4 0.0 0.0003 19.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family APH PF01636.23 CRK33088.1 - 8.1e-14 52.1 0.1 2.1e-13 50.8 0.1 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CRK33088.1 - 0.016 14.8 0.1 1.3 8.5 0.0 2.4 2 0 0 2 2 2 0 Choline/ethanolamine kinase Fructosamin_kin PF03881.14 CRK33088.1 - 0.025 13.8 0.0 0.046 12.9 0.0 1.4 1 0 0 1 1 1 0 Fructosamine kinase Pex26 PF07163.12 CRK33089.1 - 0.00056 19.3 3.1 0.00066 19.1 3.1 1.1 1 0 0 1 1 1 1 Pex26 protein Mei5 PF10376.9 CRK33089.1 - 0.045 13.6 8.2 0.052 13.4 8.2 1.2 1 0 0 1 1 1 0 Double-strand recombination repair protein DUF3570 PF12094.8 CRK33089.1 - 0.13 11.0 0.0 0.13 11.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3570) AAA_23 PF13476.6 CRK33089.1 - 0.41 11.1 6.6 0.46 11.0 6.6 1.1 1 0 0 1 1 1 0 AAA domain DUF3381 PF11861.8 CRK33089.1 - 1.1 9.1 13.8 1.6 8.5 13.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Med3 PF11593.8 CRK33090.1 - 0.24 10.5 5.8 0.25 10.5 5.8 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Helicase_C PF00271.31 CRK33091.1 - 2.8e-13 50.2 0.0 3.8e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PRAI PF00697.22 CRK33091.1 - 0.0024 17.7 0.1 0.0028 17.4 0.1 1.1 1 0 0 1 1 1 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase SpoU_methylase PF00588.19 CRK33091.1 - 0.022 14.9 0.1 0.1 12.8 0.1 1.8 1 1 1 2 2 2 0 SpoU rRNA Methylase family Sec63 PF02889.16 CRK33094.1 - 1.4e-05 24.4 0.0 1.9e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 CRK33094.1 - 0.0007 19.4 0.0 0.0089 15.8 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_PWI PF18149.1 CRK33094.1 - 0.00084 19.5 0.0 0.0014 18.8 0.0 1.3 1 0 0 1 1 1 1 N-terminal helicase PWI domain AAA_22 PF13401.6 CRK33094.1 - 0.14 12.4 0.0 0.45 10.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain Ras PF00071.22 CRK33095.1 - 6.7e-40 136.3 0.0 1.4e-37 128.8 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 CRK33095.1 - 1e-32 112.9 0.0 1.8e-32 112.1 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CRK33095.1 - 6.2e-11 42.1 0.0 9.7e-11 41.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CRK33095.1 - 7.1e-06 26.1 0.0 1.4e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 CRK33095.1 - 0.0038 16.7 0.0 0.0056 16.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 CRK33095.1 - 0.014 15.8 0.1 0.02 15.3 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain Dynamin_N PF00350.23 CRK33095.1 - 0.053 13.6 0.0 0.097 12.7 0.0 1.5 1 0 0 1 1 1 0 Dynamin family AAA_24 PF13479.6 CRK33095.1 - 0.098 12.4 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 CRK33095.1 - 0.1 12.6 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.9 CRK33095.1 - 0.12 12.1 0.0 2.9 7.6 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.29 CRK33095.1 - 0.2 12.1 0.0 0.55 10.7 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 CRK33095.1 - 0.21 11.8 0.7 0.44 10.8 0.1 2.0 2 1 0 2 2 2 0 AAA domain Gtr1_RagA PF04670.12 CRK33095.1 - 0.25 10.7 0.0 0.42 9.9 0.0 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Hydrophobin_2 PF06766.11 CRK33096.1 - 9.4e-25 86.4 11.2 1.2e-24 86.0 11.2 1.1 1 0 0 1 1 1 1 Fungal hydrophobin CRAL_TRIO PF00650.20 CRK33099.1 - 3.1e-16 59.5 0.0 3.2e-16 59.5 0.0 1.0 1 0 0 1 1 1 1 CRAL/TRIO domain N6-adenineMlase PF10237.9 CRK33099.1 - 0.065 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Probable N6-adenine methyltransferase cNMP_binding PF00027.29 CRK33100.1 - 7.1e-14 51.7 0.0 8.8e-14 51.3 0.0 1.1 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Usp PF00582.26 CRK33101.1 - 4.5e-06 27.2 0.1 5.5e-06 26.9 0.1 1.2 1 0 0 1 1 1 1 Universal stress protein family ALG11_N PF15924.5 CRK33102.1 - 3.6e-35 121.9 0.0 4e-35 121.8 0.0 1.0 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus KAsynt_C_assoc PF16197.5 CRK33103.1 - 4.2e-20 72.3 0.0 5.1e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Peptidase_S8 PF00082.22 CRK33105.1 - 9.4e-42 143.3 0.2 1.6e-41 142.5 0.2 1.4 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 CRK33105.1 - 2.6e-07 31.3 0.0 5.7e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Fn3-like domain Lactamase_B PF00753.27 CRK33107.1 - 5.6e-09 36.3 0.5 1.1e-08 35.4 0.5 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CRK33107.1 - 0.00014 21.5 0.8 0.019 14.5 0.8 2.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Amidohydro_2 PF04909.14 CRK33107.1 - 0.054 13.3 0.0 0.093 12.5 0.0 1.4 1 0 0 1 1 1 0 Amidohydrolase HicA_toxin PF07927.12 CRK33107.1 - 0.08 13.0 0.2 2.9 8.0 0.0 2.6 2 1 0 2 2 2 0 HicA toxin of bacterial toxin-antitoxin, Shikimate_dh_N PF08501.11 CRK33107.1 - 0.18 12.1 0.0 1.6 9.0 0.0 2.2 2 0 0 2 2 2 0 Shikimate dehydrogenase substrate binding domain Cu_amine_oxid PF01179.20 CRK33110.1 - 1.4e-160 534.8 0.0 1.8e-160 534.4 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 CRK33110.1 - 1.1e-20 73.9 0.2 2.3e-20 72.9 0.2 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 CRK33110.1 - 8e-14 51.6 0.0 1.4e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain RdgC PF04381.12 CRK33110.1 - 0.25 10.5 0.0 0.4 9.9 0.0 1.2 1 0 0 1 1 1 0 Putative exonuclease, RdgC Peptidase_S8 PF00082.22 CRK33114.1 - 4.5e-45 154.2 0.0 1.1e-44 152.9 0.0 1.5 1 1 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 CRK33114.1 - 8.1e-05 23.3 0.0 0.00055 20.6 0.0 2.4 2 0 0 2 2 2 1 Fn3-like domain PA PF02225.22 CRK33114.1 - 0.00045 20.2 0.2 0.00045 20.2 0.2 2.5 2 0 0 2 2 2 1 PA domain Inhibitor_I9 PF05922.16 CRK33114.1 - 0.0061 17.2 0.1 0.016 15.9 0.1 1.7 1 0 0 1 1 1 1 Peptidase inhibitor I9 Glyco_hydro_47 PF01532.20 CRK33120.1 - 4.9e-32 111.4 0.0 6.4e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 AAA PF00004.29 CRK33121.1 - 2.7e-07 31.1 0.0 4.7e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CRK33121.1 - 0.00052 20.4 0.7 0.0011 19.4 0.1 1.7 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 CRK33121.1 - 0.001 18.8 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CRK33121.1 - 0.0024 18.2 0.1 0.0055 17.0 0.1 1.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CRK33121.1 - 0.0042 17.6 0.7 0.074 13.6 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 CRK33121.1 - 0.0087 16.1 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.6 CRK33121.1 - 0.014 15.8 0.0 0.036 14.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain DnaB_C PF03796.15 CRK33121.1 - 0.069 12.5 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain HA PF03457.14 CRK33121.1 - 0.073 13.4 0.5 0.12 12.7 0.5 1.6 1 1 0 1 1 1 0 Helicase associated domain AAA_33 PF13671.6 CRK33121.1 - 0.075 13.2 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 CRK33121.1 - 0.093 12.5 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 CRK33121.1 - 0.14 11.9 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 CRK33121.1 - 0.16 11.4 0.1 0.22 10.9 0.1 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CRK33121.1 - 0.16 11.8 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 CRK33121.1 - 0.2 11.6 0.0 0.36 10.7 0.0 1.4 1 0 0 1 1 1 0 NTPase RNA_helicase PF00910.22 CRK33121.1 - 0.2 12.0 0.0 0.38 11.2 0.0 1.4 1 0 0 1 1 1 0 RNA helicase ATPase PF06745.13 CRK33121.1 - 0.23 10.8 0.1 0.37 10.1 0.1 1.3 1 0 0 1 1 1 0 KaiC TIP49 PF06068.13 CRK33121.1 - 0.24 10.6 0.0 0.26 10.5 0.0 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain Cation_efflux PF01545.21 CRK33122.1 - 1.3e-18 67.5 3.7 1.5e-18 67.3 3.7 1.0 1 0 0 1 1 1 1 Cation efflux family TcpE PF12648.7 CRK33122.1 - 0.69 10.5 5.8 1.1 9.8 0.4 2.1 2 0 0 2 2 2 0 TcpE family E1_dh PF00676.20 CRK33124.1 - 3.2e-48 164.2 1.2 3.5e-48 164.1 1.2 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 CRK33124.1 - 0.00084 18.6 0.1 0.0011 18.2 0.1 1.2 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Rubredoxin_C PF18267.1 CRK33125.1 - 8.3e-05 22.4 0.0 0.057 13.4 0.0 2.4 2 0 0 2 2 2 2 Rubredoxin NAD+ reductase C-terminal domain Fer2_BFD PF04324.15 CRK33125.1 - 0.0028 18.0 0.6 0.0044 17.4 0.6 1.3 1 0 0 1 1 1 1 BFD-like [2Fe-2S] binding domain zf-C2H2 PF00096.26 CRK33126.1 - 0.009 16.4 2.7 0.009 16.4 2.7 4.9 4 0 0 4 4 4 1 Zinc finger, C2H2 type Defensin_beta PF00711.19 CRK33126.1 - 0.25 11.4 6.5 7.7 6.6 0.7 2.8 2 0 0 2 2 2 0 Beta defensin DUF1540 PF07561.11 CRK33126.1 - 0.62 10.4 6.9 13 6.2 0.7 3.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1540) ResIII PF04851.15 CRK33127.1 - 5.8e-22 78.5 0.0 1.1e-21 77.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CRK33127.1 - 8.1e-21 74.4 0.0 1.7e-20 73.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CRK33127.1 - 5.6e-18 65.3 0.2 2.8e-17 63.0 0.0 2.2 3 0 0 3 3 3 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 CRK33127.1 - 1.1e-06 28.5 0.1 1.8e-06 27.8 0.1 1.3 1 0 0 1 1 1 1 SWI2/SNF2 ATPase AAA_22 PF13401.6 CRK33127.1 - 0.013 15.8 0.0 0.05 13.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain TAP_C PF03943.13 CRK33128.1 - 1.8e-16 59.5 0.8 5.4e-16 58.0 0.1 2.0 2 0 0 2 2 2 1 TAP C-terminal domain RRM_9 PF18444.1 CRK33128.1 - 7.9e-06 25.6 0.3 5.2e-05 23.0 0.4 2.3 2 1 0 2 2 2 1 RNA recognition motif LRR_4 PF12799.7 CRK33128.1 - 4.8e-05 23.6 1.4 0.0019 18.6 0.5 2.9 1 1 2 3 3 3 2 Leucine Rich repeats (2 copies) NTF2 PF02136.20 CRK33128.1 - 0.00016 22.2 0.0 0.00054 20.5 0.0 2.0 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain LRR_8 PF13855.6 CRK33128.1 - 0.0052 16.5 0.1 0.017 14.9 0.1 2.0 1 1 0 1 1 1 1 Leucine rich repeat LRR_9 PF14580.6 CRK33128.1 - 0.011 15.3 0.1 0.019 14.5 0.1 1.4 1 0 0 1 1 1 0 Leucine-rich repeat TFIIA PF03153.13 CRK33129.1 - 0.86 9.5 17.5 0.92 9.4 17.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GMC_oxred_N PF00732.19 CRK33133.1 - 1.2e-07 31.4 0.0 1.5e-07 31.1 0.0 1.0 1 0 0 1 1 1 1 GMC oxidoreductase Aldedh PF00171.22 CRK33134.1 - 3.2e-48 164.4 0.1 3.5e-48 164.3 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Aldo_ket_red PF00248.21 CRK33135.1 - 2.5e-33 115.6 0.0 4.2e-32 111.5 0.0 2.1 1 1 0 1 1 1 1 Aldo/keto reductase family TPR_17 PF13431.6 CRK33138.1 - 0.015 15.6 0.0 10 6.8 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 CRK33138.1 - 0.019 14.6 1.0 29 4.4 0.1 3.8 3 0 0 3 3 3 0 TPR repeat TPR_14 PF13428.6 CRK33138.1 - 0.98 10.4 10.6 3.2 8.8 0.4 4.7 4 1 0 4 4 4 0 Tetratricopeptide repeat DSS1_SEM1 PF05160.13 CRK33139.1 - 9.2e-24 83.3 14.6 1.3e-23 82.8 14.6 1.2 1 0 0 1 1 1 1 DSS1/SEM1 family ArfGap PF01412.18 CRK33139.1 - 0.11 12.5 0.8 0.15 12.1 0.8 1.2 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf Cwf_Cwc_15 PF04889.12 CRK33139.1 - 0.24 11.1 9.7 0.27 10.9 9.7 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CwfJ_C_2 PF04676.14 CRK33140.1 - 4.6e-27 94.8 0.1 9.9e-27 93.7 0.1 1.6 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.15 CRK33140.1 - 3.3e-26 91.5 0.0 4.5e-26 91.1 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 2OG-FeII_Oxy_2 PF13532.6 CRK33140.1 - 0.0066 16.6 0.0 0.01 16.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily VPS28 PF03997.12 CRK33145.1 - 3.8e-20 72.4 0.1 4.6e-20 72.1 0.1 1.1 1 0 0 1 1 1 1 VPS28 protein Spb1_C PF07780.12 CRK33148.1 - 7.1e-61 205.5 10.1 7.9e-61 205.4 10.1 1.0 1 0 0 1 1 1 1 Spb1 C-terminal domain Adeno_VII PF03228.14 CRK33148.1 - 0.023 15.4 4.0 0.024 15.3 3.6 1.4 1 1 0 1 1 1 0 Adenoviral core protein VII SOAR PF16533.5 CRK33148.1 - 0.13 12.2 3.4 0.19 11.7 3.4 1.3 1 0 0 1 1 1 0 STIM1 Orai1-activating region CBFB_NFYA PF02045.15 CRK33151.1 - 1.5e-28 99.1 4.6 3.1e-28 98.2 4.6 1.5 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Hus1 PF04005.12 CRK33151.1 - 0.087 11.9 0.1 0.14 11.3 0.1 1.2 1 0 0 1 1 1 0 Hus1-like protein APH PF01636.23 CRK33152.1 - 4.8e-28 98.7 9.0 8.3e-26 91.4 3.1 2.5 2 0 0 2 2 2 2 Phosphotransferase enzyme family Mad3_BUB1_II PF08171.11 CRK33152.1 - 1.4e-15 57.2 0.0 2.7e-07 30.6 0.0 3.7 3 0 0 3 3 3 2 Mad3/BUB1 homology region 2 Pkinase PF00069.25 CRK33152.1 - 6.4e-10 38.8 0.0 1.9e-07 30.8 0.0 3.7 4 0 0 4 4 4 1 Protein kinase domain Mad3_BUB1_I PF08311.12 CRK33152.1 - 1.9e-06 27.9 0.5 5.2e-06 26.5 0.5 1.8 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Kdo PF06293.14 CRK33152.1 - 7.6e-05 22.2 0.1 0.26 10.6 0.1 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family CssAB PF16831.5 CRK33152.1 - 0.021 15.2 0.0 13 6.1 0.0 2.5 2 0 0 2 2 2 0 CS6 fimbrial subunits A and B, Coli surface antigen 6 Pkinase_Tyr PF07714.17 CRK33152.1 - 0.026 13.8 0.1 0.94 8.7 0.0 2.8 2 1 0 2 2 2 0 Protein tyrosine kinase DAGAT PF03982.13 CRK33153.1 - 1.1e-54 185.4 0.0 1.5e-54 185.0 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Rer1 PF03248.13 CRK33153.1 - 0.028 14.2 0.9 0.046 13.5 0.9 1.2 1 0 0 1 1 1 0 Rer1 family DUF4110 PF13422.6 CRK33154.1 - 3.9e-30 103.8 1.5 3.9e-30 103.8 1.5 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4110) Kelch_5 PF13854.6 CRK33154.1 - 1.4e-14 53.7 0.1 1e-07 31.8 0.0 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 CRK33154.1 - 5.8e-14 52.0 5.1 2.3e-05 24.5 0.0 5.0 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_4 PF13418.6 CRK33154.1 - 2.6e-13 49.7 9.5 4.5e-05 23.4 0.0 5.6 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.15 CRK33154.1 - 1.7e-12 46.8 0.6 0.001 18.9 0.0 4.9 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.6 CRK33154.1 - 3.8e-10 39.7 1.5 5.7e-05 23.3 0.1 4.4 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.25 CRK33154.1 - 2.7e-09 36.4 0.4 0.00051 19.6 0.0 3.8 4 0 0 4 4 4 2 Kelch motif BUD22 PF09073.10 CRK33154.1 - 0.005 16.3 14.1 0.0077 15.6 14.1 1.3 1 0 0 1 1 1 1 BUD22 CDC45 PF02724.14 CRK33154.1 - 0.022 13.0 11.2 0.036 12.4 11.2 1.3 1 0 0 1 1 1 0 CDC45-like protein Mpp10 PF04006.12 CRK33154.1 - 1.6 7.1 21.6 2 6.8 21.6 1.2 1 0 0 1 1 1 0 Mpp10 protein PI3K_1B_p101 PF10486.9 CRK33154.1 - 2.6 5.7 4.0 3.5 5.3 4.0 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit PTPRCAP PF15713.5 CRK33154.1 - 2.6 8.3 20.6 0.16 12.2 13.5 2.4 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated TGT_C2 PF14810.6 CRK33155.1 - 0.019 15.1 0.1 0.027 14.6 0.1 1.2 1 0 0 1 1 1 0 Patch-forming domain C2 of tRNA-guanine transglycosylase Tmemb_14 PF03647.13 CRK33155.1 - 0.11 13.3 0.0 0.13 13.0 0.0 1.2 1 0 0 1 1 1 0 Transmembrane proteins 14C WD40 PF00400.32 CRK33156.1 - 0.003 18.3 3.2 0.0054 17.6 0.2 2.3 2 0 0 2 2 2 1 WD domain, G-beta repeat Mub_B2 PF17966.1 CRK33156.1 - 8.5 7.2 6.8 28 5.5 6.8 2.1 1 1 0 1 1 1 0 Mub B2-like domain ALAD PF00490.21 CRK33162.1 - 8.7e-40 136.8 0.0 1.4e-39 136.2 0.0 1.3 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase BicD PF09730.9 CRK33162.1 - 0.12 10.8 0.1 0.17 10.3 0.1 1.1 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D Trimer_CC PF08954.11 CRK33162.1 - 0.15 11.6 0.1 0.66 9.6 0.1 2.1 1 0 0 1 1 1 0 Trimerisation motif Vps62 PF06101.11 CRK33163.1 - 6.6e-11 41.2 0.5 1.1e-10 40.5 0.5 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 62 Phosphorylase PF00343.20 CRK33164.1 - 5.1e-63 213.5 0.3 5.6e-63 213.3 0.3 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Pkinase PF00069.25 CRK33166.1 - 5.3e-22 78.4 0.0 6e-22 78.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK33166.1 - 1e-08 34.8 0.0 1.3e-08 34.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Hid1 PF12722.7 CRK33167.1 - 4 5.5 4.6 4.3 5.3 4.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PGC7_Stella PF15549.6 CRK33168.1 - 0.053 13.5 1.6 0.079 13.0 1.6 1.3 1 1 0 1 1 1 0 PGC7/Stella/Dppa3 domain Pkinase PF00069.25 CRK33169.1 - 2.5e-31 109.0 0.0 3e-31 108.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK33169.1 - 2.5e-11 43.3 0.0 3e-11 43.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CRK33169.1 - 0.1 11.9 0.0 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 Kinase-like RNB PF00773.19 CRK33171.1 - 9e-37 127.1 0.0 1e-36 127.0 0.0 1.0 1 0 0 1 1 1 1 RNB domain CHASE5 PF17149.4 CRK33171.1 - 0.15 12.0 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 Periplasmic sensor domain found in signal transduction proteins DUF2205 PF10224.9 CRK33172.1 - 0.00033 20.6 0.3 0.0006 19.8 0.3 1.5 1 0 0 1 1 1 1 Short coiled-coil protein DUF4573 PF15140.6 CRK33172.1 - 0.014 15.2 4.7 0.094 12.5 4.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4573) IMUP PF15761.5 CRK33172.1 - 0.02 15.6 2.4 0.029 15.1 2.4 1.3 1 0 0 1 1 1 0 Immortalisation up-regulated protein ABC_tran PF00005.27 CRK33173.1 - 1.1e-34 119.9 0.0 5.9e-34 117.5 0.0 2.1 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.23 CRK33173.1 - 3.3e-29 102.4 11.0 3.3e-29 102.4 11.0 1.6 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.19 CRK33173.1 - 4.6e-06 26.2 1.0 0.00064 19.2 0.1 2.2 1 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 CRK33173.1 - 0.0011 19.2 0.3 0.0056 17.0 0.3 2.0 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 CRK33173.1 - 0.004 16.9 0.0 0.0062 16.3 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 CRK33173.1 - 0.0061 16.3 0.2 0.015 15.0 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 CRK33173.1 - 0.017 14.9 0.1 0.079 12.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 CRK33173.1 - 0.034 14.5 1.5 0.55 10.6 1.5 2.4 1 1 0 1 1 1 0 AAA ATPase domain SbcCD_C PF13558.6 CRK33173.1 - 0.047 13.9 0.5 0.42 10.9 0.5 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.6 CRK33173.1 - 0.059 13.1 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF3108 PF11306.8 CRK33173.1 - 0.13 12.3 0.1 0.22 11.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3108) Yip1 PF04893.17 CRK33173.1 - 1.5 8.5 10.6 2 8.1 1.0 2.5 2 0 0 2 2 2 0 Yip1 domain WD40 PF00400.32 CRK33177.1 - 3.8e-07 30.7 2.9 0.00073 20.3 0.1 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK33177.1 - 0.033 14.5 0.0 0.93 9.8 0.0 2.2 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain FlaG PF03646.15 CRK33177.1 - 0.14 12.4 0.0 0.35 11.0 0.0 1.6 2 0 0 2 2 2 0 FlaG protein PAPS_reduct PF01507.19 CRK33183.1 - 2.7e-05 24.3 0.1 4.2e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family DUF3723 PF12520.8 CRK33192.1 - 8.2e-54 183.1 0.0 4.1e-47 161.0 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3723) zf-C2H2_4 PF13894.6 CRK33200.1 - 0.039 14.8 4.8 4.1 8.5 0.0 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 CRK33200.1 - 0.04 14.4 5.9 0.22 12.0 0.0 3.0 2 1 0 2 2 2 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CRK33200.1 - 3.3 8.3 8.1 0.26 11.8 1.3 2.5 2 1 0 2 2 2 0 Zinc-finger double domain SRP-alpha_N PF04086.13 CRK33207.1 - 6.7e-14 52.5 0.0 6.7e-14 52.5 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal DUF3549 PF12069.8 CRK33214.1 - 0.005 15.9 0.2 0.0054 15.8 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3549) BLOC1_2 PF10046.9 CRK33214.1 - 0.069 13.5 0.0 0.33 11.3 0.0 1.8 1 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ApoC-I PF04691.12 CRK33214.1 - 0.084 12.8 0.0 0.26 11.2 0.0 1.9 1 0 0 1 1 1 0 Apolipoprotein C-I (ApoC-1) Utp12 PF04003.12 CRK33214.1 - 0.09 13.1 0.0 0.19 12.1 0.0 1.8 1 1 0 1 1 1 0 Dip2/Utp12 Family HCO3_cotransp PF00955.21 CRK33217.1 - 7.2e-20 71.3 0.0 8.3e-20 71.1 0.0 1.0 1 0 0 1 1 1 1 HCO3- transporter family Asp PF00026.23 CRK33221.1 - 5.9e-28 98.2 0.0 6.3e-28 98.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease QueF_N PF14819.6 CRK33221.1 - 0.087 13.1 0.1 0.16 12.3 0.1 1.4 1 0 0 1 1 1 0 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term EPL1 PF10513.9 CRK33225.1 - 3e-18 66.7 0.5 4.2e-18 66.2 0.5 1.2 1 0 0 1 1 1 1 Enhancer of polycomb-like DUF3433 PF11915.8 CRK33231.1 - 5e-10 39.7 0.1 1.2e-09 38.4 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3433) PIG-L PF02585.17 CRK33233.1 - 3.4e-25 89.2 0.1 8.7e-25 87.9 0.1 1.8 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase GTP_EFTU_D2 PF03144.25 CRK33233.1 - 1.6e-09 38.1 0.3 9.1e-09 35.6 0.3 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 CRK33233.1 - 0.0002 21.7 0.0 0.00061 20.1 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU PF00009.27 CRK33233.1 - 0.003 17.1 0.0 0.0052 16.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CRK33233.1 - 0.0034 17.4 0.0 0.0085 16.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 CRK33233.1 - 0.022 14.9 0.0 0.041 14.1 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 CRK33233.1 - 0.12 12.4 0.2 0.22 11.5 0.2 1.4 1 0 0 1 1 1 0 Dynamin family Ras PF00071.22 CRK33233.1 - 0.16 11.6 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Ras family Cwf_Cwc_15 PF04889.12 CRK33235.1 - 0.33 10.7 6.3 0.42 10.3 6.3 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NUDIX PF00293.28 CRK33242.1 - 6.9e-16 58.5 0.1 9.7e-16 58.0 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 CRK33242.1 - 2.3e-05 24.4 0.0 6.2e-05 22.9 0.0 1.7 1 1 0 1 1 1 1 NUDIX domain TPR_9 PF13371.6 CRK33247.1 - 0.17 12.0 0.0 0.92 9.7 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat FBPase PF00316.20 CRK33251.1 - 8.3e-07 28.7 0.1 1.3e-06 28.0 0.1 1.3 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain NdhM PF10664.9 CRK33251.1 - 0.08 13.2 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 Cyanobacterial and plastid NDH-1 subunit M Sortilin-Vps10 PF15902.5 CRK33254.1 - 1.2e-52 179.2 1.3 1.3e-52 179.1 1.3 1.0 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, DUF2167 PF09935.9 CRK33254.1 - 0.0029 16.8 0.0 0.0035 16.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2167) Rota_NS53 PF00981.17 CRK33257.1 - 1 8.2 3.6 1 8.1 3.6 1.0 1 0 0 1 1 1 0 Rotavirus RNA-binding Protein 53 (NS53) Sugar_tr PF00083.24 CRK33261.1 - 1.5e-17 63.6 12.7 1.7e-17 63.5 12.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK33261.1 - 0.00012 21.1 16.8 0.00013 21.0 16.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Aminotran_1_2 PF00155.21 CRK33266.1 - 2.8e-07 30.1 0.0 3.1e-07 29.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II AUX_IAA PF02309.16 CRK33270.1 - 0.084 12.7 0.4 0.09 12.6 0.4 1.1 1 0 0 1 1 1 0 AUX/IAA family Inhibitor_I9 PF05922.16 CRK33278.1 - 8.5e-17 61.6 0.1 1.4e-16 60.9 0.1 1.3 1 0 0 1 1 1 1 Peptidase inhibitor I9 RIBIOP_C PF04950.12 CRK33295.1 - 1.5e-96 323.3 0.0 3.6e-96 322.0 0.0 1.5 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 CRK33295.1 - 3.3e-16 59.1 0.0 7.3e-16 58.0 0.0 1.6 1 0 0 1 1 1 1 AARP2CN (NUC121) domain BING4CT PF08149.11 CRK33297.1 - 5.5e-38 128.6 0.0 3.8e-34 116.3 0.0 3.5 3 0 0 3 3 3 2 BING4CT (NUC141) domain ANAPC4_WD40 PF12894.7 CRK33297.1 - 1.7e-07 31.5 1.6 7 7.0 0.0 6.0 3 1 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CRK33297.1 - 4.2e-05 24.2 0.0 1 10.3 0.0 4.5 4 0 0 4 4 4 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 CRK33297.1 - 0.0031 16.6 0.0 0.008 15.3 0.0 1.6 1 0 0 1 1 1 1 Coatomer WD associated region Cytochrom_D1 PF02239.16 CRK33297.1 - 0.004 15.7 0.0 0.59 8.6 0.0 2.3 2 0 0 2 2 2 2 Cytochrome D1 heme domain PTH2 PF01981.16 CRK33299.1 - 3e-44 150.1 0.5 4.2e-44 149.6 0.5 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 SpoU_sub_bind PF08032.12 CRK33299.1 - 0.1 12.9 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 RNA 2'-O ribose methyltransferase substrate binding CPT PF07931.12 CRK33300.1 - 2.7e-05 24.1 0.0 4.7e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.6 CRK33300.1 - 0.0014 19.2 0.1 0.0068 17.0 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 CRK33300.1 - 0.003 17.8 0.0 0.0052 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain PRK PF00485.18 CRK33300.1 - 0.02 14.6 0.0 0.043 13.6 0.0 1.7 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family G-alpha PF00503.20 CRK33300.1 - 0.027 13.6 0.0 0.038 13.1 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit AAA_33 PF13671.6 CRK33300.1 - 0.044 14.0 0.0 0.13 12.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CRK33300.1 - 0.072 13.5 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 CRK33300.1 - 0.091 13.0 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 CRK33300.1 - 0.16 11.3 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin Glyco_hydro_15 PF00723.21 CRK33303.1 - 8.5e-78 262.1 0.0 2.5e-63 214.5 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolases family 15 CBM_20 PF00686.19 CRK33303.1 - 7e-30 102.8 0.0 1.2e-29 102.0 0.0 1.4 1 0 0 1 1 1 1 Starch binding domain SART-1 PF03343.13 CRK33305.1 - 3.8e-144 481.7 57.1 5e-144 481.3 57.1 1.1 1 0 0 1 1 1 1 SART-1 family LEA_2 PF03168.13 CRK33305.1 - 0.00023 21.6 0.7 1.3 9.6 0.0 2.8 2 0 0 2 2 2 2 Late embryogenesis abundant protein Peptidase_M56 PF05569.11 CRK33307.1 - 0.05 12.8 0.0 0.085 12.0 0.0 1.3 1 0 0 1 1 1 0 BlaR1 peptidase M56 OTCace PF00185.24 CRK33309.1 - 7.4e-44 149.6 0.0 1.3e-43 148.8 0.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 CRK33309.1 - 1.2e-43 148.6 0.1 1.7e-43 148.2 0.1 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain ACT PF01842.25 CRK33311.1 - 3.8e-15 55.4 0.1 7e-15 54.5 0.1 1.5 1 0 0 1 1 1 1 ACT domain ALS_ss_C PF10369.9 CRK33311.1 - 1.2e-14 54.2 0.0 1.3e-13 51.0 0.0 2.3 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT_5 PF13710.6 CRK33311.1 - 2e-08 34.0 0.0 4.4e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 ACT domain Myc-LZ PF02344.15 CRK33311.1 - 0.13 12.4 0.4 0.39 10.8 0.4 1.8 1 0 0 1 1 1 0 Myc leucine zipper domain Glyco_hydro_61 PF03443.14 CRK33312.1 - 4.8e-55 186.7 0.2 5.5e-55 186.5 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CSD PF00313.22 CRK33312.1 - 0.16 11.8 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 'Cold-shock' DNA-binding domain DUF974 PF06159.13 CRK33314.1 - 2.2e-153 509.1 0.0 1.3e-75 254.4 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF974) Glyco_hydro_61 PF03443.14 CRK33314.1 - 5.8e-53 179.9 0.1 1.1e-52 179.0 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 KH_1 PF00013.29 CRK33314.1 - 2.4e-14 52.9 0.0 0.0017 18.2 0.0 4.6 4 0 0 4 4 4 2 KH domain PCSK9_C3 PF18463.1 CRK33314.1 - 0.00022 21.4 0.4 0.98 9.7 0.1 2.6 2 0 0 2 2 2 2 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain Trp_repressor PF01371.19 CRK33314.1 - 0.033 14.3 0.1 17 5.6 0.0 2.7 2 0 0 2 2 2 0 Trp repressor protein TetR_C_35 PF18556.1 CRK33314.1 - 0.041 14.0 0.0 21 5.3 0.0 2.8 2 0 0 2 2 2 0 Bacterial Tetracyclin repressor, C-terminal domain DUF5067 PF16729.5 CRK33314.1 - 0.082 12.8 0.0 22 5.0 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5067) DUF5114 PF17141.4 CRK33314.1 - 0.11 13.1 0.3 49 4.5 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF5114) HJURP_mid PF12346.8 CRK33314.1 - 0.11 12.9 10.5 2.3 8.7 1.7 2.6 2 0 0 2 2 2 0 Holliday junction recognition protein-associated repeat DUF4410 PF14366.6 CRK33314.1 - 0.25 11.2 2.9 13 5.7 0.2 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4410) Trypan_PARP PF05887.11 CRK33314.1 - 0.67 9.9 8.0 9.1 6.3 0.5 2.7 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) BAF1_ABF1 PF04684.13 CRK33314.1 - 1.2 8.1 13.5 3 6.8 3.5 2.1 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor uDENN PF03456.18 CRK33319.1 - 2.2e-14 53.9 0.1 6.1e-14 52.5 0.0 1.8 2 0 0 2 2 2 1 uDENN domain DENN PF02141.21 CRK33321.1 - 1.4e-53 181.6 0.0 2.1e-53 181.0 0.0 1.3 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.19 CRK33321.1 - 7.2e-16 57.9 0.7 3.7e-15 55.7 0.7 2.1 2 0 0 2 2 2 1 dDENN domain C1_2 PF03107.16 CRK33321.1 - 0.019 15.3 5.2 0.037 14.4 5.2 1.4 1 0 0 1 1 1 0 C1 domain SPA PF08616.10 CRK33321.1 - 0.083 12.9 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Stabilization of polarity axis PHD PF00628.29 CRK33321.1 - 1.1 9.2 8.3 2.5 8.1 8.3 1.6 1 0 0 1 1 1 0 PHD-finger C1_1 PF00130.22 CRK33321.1 - 4.7 7.2 13.3 0.55 10.2 9.1 1.7 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SNAP PF14938.6 CRK33322.1 - 3.5e-111 371.2 16.5 4e-111 371.0 16.5 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_7 PF13176.6 CRK33322.1 - 6.2e-05 22.7 8.8 0.03 14.4 0.3 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 CRK33322.1 - 0.00014 22.1 17.7 0.1 12.9 1.3 3.8 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 CRK33322.1 - 0.0014 18.7 11.3 0.19 12.0 0.3 4.8 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 CRK33322.1 - 0.007 16.4 21.9 3.7 7.9 0.3 5.8 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_6 PF13174.6 CRK33322.1 - 0.073 13.7 19.6 4.8 8.0 0.5 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_3 PF07720.12 CRK33322.1 - 0.079 13.0 4.8 1.3 9.1 1.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 CRK33322.1 - 0.24 12.3 20.9 10 7.2 0.4 5.4 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 CRK33322.1 - 0.33 10.8 15.4 2.3 8.2 0.2 5.0 4 1 1 5 5 5 0 Tetratricopeptide repeat Glu-tRNAGln PF02686.15 CRK33323.1 - 7.8e-05 22.9 0.0 0.00017 21.8 0.0 1.6 1 1 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit DUF726 PF05277.12 CRK33324.1 - 6.9e-96 321.1 0.1 1.1e-95 320.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) IMS PF00817.20 CRK33324.1 - 6.7e-38 130.0 0.0 1.6e-37 128.8 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family SNAP PF14938.6 CRK33324.1 - 2.2e-14 53.6 0.2 3.7e-14 52.8 0.2 1.3 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP IMS_C PF11799.8 CRK33324.1 - 2.1e-10 41.3 0.1 5.7e-10 39.9 0.1 1.8 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain FAD_binding_3 PF01494.19 CRK33324.1 - 1.8e-05 24.2 1.4 0.00027 20.3 1.4 2.2 1 1 0 1 1 1 1 FAD binding domain Thioesterase PF00975.20 CRK33324.1 - 0.0022 18.2 0.0 0.0068 16.5 0.0 1.8 1 0 0 1 1 1 1 Thioesterase domain IMS_HHH PF11798.8 CRK33324.1 - 0.0064 16.7 0.0 0.02 15.2 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif PE-PPE PF08237.11 CRK33324.1 - 0.018 14.6 0.0 0.066 12.7 0.0 1.9 2 0 0 2 2 2 0 PE-PPE domain Glu-tRNAGln PF02686.15 CRK33325.1 - 2.1e-06 27.9 0.0 5.9e-06 26.5 0.0 1.8 1 1 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit DUF726 PF05277.12 CRK33326.1 - 7.7e-96 321.0 0.1 1.3e-95 320.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF726) IMS PF00817.20 CRK33326.1 - 7.5e-38 129.9 0.0 1.7e-37 128.7 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family FAD_binding_3 PF01494.19 CRK33326.1 - 4.8e-11 42.5 3.9 7.2e-10 38.6 3.9 2.2 1 1 0 1 1 1 1 FAD binding domain IMS_C PF11799.8 CRK33326.1 - 7.5e-10 39.5 0.1 2.2e-09 38.0 0.1 1.8 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain NAD_binding_8 PF13450.6 CRK33326.1 - 1.8e-06 28.0 0.4 5.1e-06 26.6 0.4 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CRK33326.1 - 0.00011 21.6 0.5 0.0016 17.7 0.8 2.3 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase IMS_HHH PF11798.8 CRK33326.1 - 0.00023 21.3 0.0 0.00069 19.8 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif DAO PF01266.24 CRK33326.1 - 0.00033 20.3 2.2 0.0008 19.1 2.2 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CRK33326.1 - 0.00035 19.8 0.9 0.00062 19.0 0.9 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 CRK33326.1 - 0.0022 18.5 0.2 0.0074 16.8 0.2 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thioesterase PF00975.20 CRK33326.1 - 0.0028 17.8 0.0 0.0067 16.6 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain Thi4 PF01946.17 CRK33326.1 - 0.013 14.8 0.1 0.025 13.8 0.1 1.4 1 0 0 1 1 1 0 Thi4 family PE-PPE PF08237.11 CRK33326.1 - 0.02 14.5 0.0 0.066 12.8 0.0 1.8 2 0 0 2 2 2 0 PE-PPE domain Trp_halogenase PF04820.14 CRK33326.1 - 0.023 13.6 0.1 0.088 11.6 0.0 1.9 2 0 0 2 2 2 0 Tryptophan halogenase HI0933_like PF03486.14 CRK33326.1 - 0.033 12.9 0.6 0.064 11.9 0.6 1.4 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.6 CRK33326.1 - 0.034 14.1 0.3 0.21 11.6 0.3 2.4 2 1 0 2 2 2 0 FAD-NAD(P)-binding ApbA PF02558.16 CRK33326.1 - 0.12 12.0 0.3 0.23 11.1 0.3 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GIDA PF01134.22 CRK33326.1 - 0.17 10.9 0.8 0.28 10.2 0.8 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 CRK33326.1 - 0.24 10.6 1.4 0.38 10.0 0.5 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 CRK33328.1 - 7.7e-31 107.3 30.6 1.1e-30 106.8 30.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily SF1-HH PF16275.5 CRK33329.1 - 4e-35 120.6 0.2 8.4e-35 119.5 0.2 1.5 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain KH_1 PF00013.29 CRK33329.1 - 0.00035 20.3 0.2 0.00075 19.3 0.2 1.7 1 1 0 1 1 1 1 KH domain MFS_1 PF07690.16 CRK33331.1 - 2.9e-06 26.4 22.6 8.2e-05 21.7 7.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily C2 PF00168.30 CRK33333.1 - 6.5e-27 93.8 0.0 5.7e-15 55.5 0.0 2.6 2 0 0 2 2 2 2 C2 domain NUC173 PF08161.12 CRK33334.1 - 8e-79 264.0 0.0 3.9e-77 258.5 0.0 2.7 2 0 0 2 2 2 1 NUC173 domain HEAT_2 PF13646.6 CRK33334.1 - 0.00036 20.9 8.6 0.03 14.7 0.1 4.8 4 0 0 4 4 4 2 HEAT repeats HEAT PF02985.22 CRK33334.1 - 0.0015 18.6 2.5 6.8 7.2 0.1 4.6 4 0 0 4 4 4 2 HEAT repeat Tti2 PF10521.9 CRK33334.1 - 0.0095 15.5 0.0 0.35 10.4 0.0 2.7 2 0 0 2 2 2 1 Tti2 family V-SNARE_C PF12352.8 CRK33335.1 - 2.2e-20 72.7 4.0 6.1e-20 71.3 4.0 1.8 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.15 CRK33335.1 - 9e-11 42.0 1.9 1.7e-10 41.2 0.8 2.0 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus Sec20 PF03908.13 CRK33335.1 - 0.00064 19.6 0.5 0.0012 18.7 0.5 1.5 1 0 0 1 1 1 1 Sec20 Fusion_gly PF00523.18 CRK33335.1 - 0.0077 14.5 0.2 0.015 13.6 0.2 1.4 1 0 0 1 1 1 1 Fusion glycoprotein F0 Use1 PF09753.9 CRK33335.1 - 0.019 14.7 4.7 0.1 12.3 4.7 2.3 1 1 0 1 1 1 0 Membrane fusion protein Use1 Tropomyosin_1 PF12718.7 CRK33335.1 - 0.027 14.6 1.4 0.027 14.6 1.4 2.3 2 1 0 2 2 2 0 Tropomyosin like Synaptobrevin PF00957.21 CRK33335.1 - 0.15 11.9 3.0 0.59 10.0 2.4 2.1 1 1 1 2 2 2 0 Synaptobrevin SNARE PF05739.19 CRK33335.1 - 3.4 7.8 10.5 0.19 11.8 1.0 3.0 4 0 0 4 4 4 0 SNARE domain C2 PF00168.30 CRK33336.1 - 5.4e-19 68.4 0.0 3.8e-15 56.1 0.0 2.6 1 1 1 2 2 2 2 C2 domain NUC173 PF08161.12 CRK33337.1 - 2e-48 164.8 0.2 9.4e-43 146.2 0.1 3.4 2 1 1 3 3 3 2 NUC173 domain HEAT PF02985.22 CRK33337.1 - 0.0018 18.4 3.7 4.9 7.7 0.1 4.8 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 CRK33337.1 - 0.0018 18.6 10.4 0.042 14.3 0.4 4.8 4 1 0 4 4 4 2 HEAT repeats Tti2 PF10521.9 CRK33337.1 - 0.0036 16.9 0.1 0.22 11.0 0.0 3.1 3 0 0 3 3 3 1 Tti2 family V-SNARE_C PF12352.8 CRK33338.1 - 6.5e-20 71.2 4.0 6.5e-20 71.2 4.0 2.1 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.15 CRK33338.1 - 4.9e-18 65.3 1.2 1e-17 64.3 0.6 1.9 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus Sec20 PF03908.13 CRK33338.1 - 0.00068 19.5 0.5 0.0014 18.5 0.5 1.5 1 0 0 1 1 1 1 Sec20 Use1 PF09753.9 CRK33338.1 - 0.0048 16.7 3.8 0.021 14.6 3.8 2.1 1 1 0 1 1 1 1 Membrane fusion protein Use1 Fusion_gly PF00523.18 CRK33338.1 - 0.0085 14.4 0.2 0.016 13.5 0.2 1.4 1 0 0 1 1 1 1 Fusion glycoprotein F0 Synaptobrevin PF00957.21 CRK33338.1 - 0.17 11.7 2.9 0.59 10.0 2.3 2.1 1 1 1 2 2 2 0 Synaptobrevin SNARE PF05739.19 CRK33338.1 - 1.1 9.3 8.6 0.24 11.4 1.1 2.9 3 0 0 3 3 3 0 SNARE domain YqjK PF13997.6 CRK33338.1 - 8.6 6.7 8.0 3.3 8.0 0.2 2.8 3 0 0 3 3 3 0 YqjK-like protein CtaG_Cox11 PF04442.14 CRK33339.1 - 1.6e-59 200.3 0.0 2.7e-59 199.5 0.0 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Isochorismatase PF00857.20 CRK33339.1 - 1.3e-07 32.0 0.0 4.2e-07 30.3 0.0 1.9 1 1 0 1 1 1 1 Isochorismatase family Dabb PF07876.12 CRK33340.1 - 3.6e-24 85.2 0.0 4.4e-24 84.9 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Ibs_toxin PF13956.6 CRK33340.1 - 1.8 8.7 7.2 2.9 8.0 7.2 1.4 1 0 0 1 1 1 0 Toxin Ibs, type I toxin-antitoxin system TRI12 PF06609.13 CRK33341.1 - 1.1e-83 281.7 32.8 4.6e-44 150.8 14.2 2.0 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 CRK33341.1 - 2.3e-25 89.3 79.6 6.3e-16 58.2 35.5 3.8 3 1 0 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK33341.1 - 7.2e-10 38.3 6.0 7.2e-10 38.3 6.0 4.6 5 1 0 5 5 5 3 Sugar (and other) transporter DUF3103 PF11301.8 CRK33341.1 - 0.058 12.2 0.7 7.7 5.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3103) TNFR_16_TM PF18422.1 CRK33341.1 - 1.8 8.6 8.7 13 5.8 1.2 2.8 2 0 0 2 2 2 0 Tumor necrosis factor receptor member 16 trans-membrane domain Glyco_hydro_43 PF04616.14 CRK33342.1 - 1e-71 241.6 1.4 1.6e-71 241.0 1.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 CRK33342.1 - 3.6e-12 46.4 0.0 1.7e-11 44.2 0.0 1.9 2 0 0 2 2 2 1 Beta xylosidase C-terminal Concanavalin A-like domain PTR2 PF00854.21 CRK33343.1 - 8.3e-72 242.2 10.2 1.2e-71 241.6 10.2 1.2 1 0 0 1 1 1 1 POT family 2-Hacid_dh_C PF02826.19 CRK33344.1 - 4.7e-45 153.1 0.1 3.7e-44 150.2 0.1 2.0 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 CRK33344.1 - 0.00097 18.8 0.1 0.024 14.2 0.0 2.5 2 1 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain AdoHcyase_NAD PF00670.21 CRK33344.1 - 0.083 13.0 0.1 0.51 10.4 0.1 2.0 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain adh_short PF00106.25 CRK33345.1 - 6.3e-33 113.9 0.0 7.6e-33 113.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK33345.1 - 2.5e-29 102.5 0.2 2.9e-29 102.3 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK33345.1 - 2.5e-09 37.3 0.2 5.3e-09 36.2 0.2 1.6 1 1 0 1 1 1 1 KR domain FLgD_tudor PF13861.6 CRK33345.1 - 0.046 14.0 0.0 0.14 12.4 0.0 1.9 2 1 0 2 2 2 0 FlgD Tudor-like domain Ras PF00071.22 CRK33346.1 - 4.6e-41 140.1 0.0 8.1e-41 139.3 0.0 1.4 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CRK33346.1 - 3.4e-29 101.5 0.0 1.1e-28 99.8 0.0 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Mannosidase_ig PF17786.1 CRK33346.1 - 1.3e-13 51.4 0.2 3.1e-13 50.1 0.2 1.7 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Arf PF00025.21 CRK33346.1 - 6.2e-10 38.8 0.0 2.2e-09 37.0 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family Ig_mannosidase PF17753.1 CRK33346.1 - 0.00073 19.2 0.0 0.0016 18.1 0.0 1.5 1 0 0 1 1 1 1 Ig-fold domain Gtr1_RagA PF04670.12 CRK33346.1 - 0.0018 17.6 0.0 0.0027 17.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CRK33346.1 - 0.0019 18.3 0.0 0.0037 17.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 CRK33346.1 - 0.011 15.5 0.0 0.74 9.5 0.0 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 CRK33346.1 - 0.035 13.5 0.0 0.059 12.8 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_33 PF13671.6 CRK33346.1 - 0.04 14.1 0.0 0.077 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Cytotoxic PF09000.10 CRK33346.1 - 0.068 13.5 0.9 0.2 12.0 0.9 1.7 1 0 0 1 1 1 0 Cytotoxic ABC_tran PF00005.27 CRK33346.1 - 0.094 13.2 0.1 0.23 12.0 0.1 1.6 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 CRK33346.1 - 0.13 12.0 0.0 0.37 10.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.12 CRK33346.1 - 0.16 11.8 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 NACHT domain RsgA_GTPase PF03193.16 CRK33346.1 - 0.17 11.8 0.0 0.58 10.0 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase Epimerase PF01370.21 CRK33348.1 - 1.2e-16 61.0 0.0 1.8e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_hydro_2 PF00703.21 CRK33348.1 - 1.9e-12 47.8 0.1 3.6e-12 46.9 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 RmlD_sub_bind PF04321.17 CRK33348.1 - 1.2e-05 24.6 0.0 2.1e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Glyco_hydro_2_N PF02837.18 CRK33348.1 - 3.5e-05 23.8 0.0 7.8e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain GDP_Man_Dehyd PF16363.5 CRK33348.1 - 3.6e-05 23.3 0.0 5.6e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 CRK33348.1 - 0.0056 15.7 0.0 0.014 14.4 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Mito_carr PF00153.27 CRK33351.1 - 1.4e-48 162.7 5.7 1.5e-17 63.3 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein ADH_N PF08240.12 CRK33352.1 - 2.8e-27 94.8 1.2 5.1e-27 93.9 1.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Ribosomal_L26 PF16906.5 CRK33353.1 - 9.8e-35 118.9 2.3 1.7e-34 118.1 2.3 1.4 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 CRK33353.1 - 8e-06 25.6 1.3 8e-06 25.6 1.3 2.7 3 0 0 3 3 3 1 KOW motif DnaJ_C PF01556.18 CRK33354.1 - 1e-36 126.3 0.0 1.4e-36 125.8 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CRK33354.1 - 9.7e-24 83.3 0.9 9.7e-24 83.3 0.9 1.6 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CRK33354.1 - 9.3e-09 35.5 23.1 1.9e-08 34.6 23.1 1.5 1 0 0 1 1 1 1 DnaJ central domain Cytochrome_C7 PF14522.6 CRK33354.1 - 3.9 7.5 9.3 0.38 10.8 2.1 2.4 1 1 0 2 2 2 0 Cytochrome c7 and related cytochrome c BRO1 PF03097.18 CRK33355.1 - 1.6e-134 448.6 1.4 4.1e-134 447.2 1.4 1.8 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 CRK33355.1 - 1.3e-73 247.8 25.8 1.3e-73 247.8 25.8 1.8 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV COG2 PF06148.11 CRK33355.1 - 0.00083 19.4 0.5 0.00083 19.4 0.5 3.7 3 1 2 5 5 5 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF416 PF04222.12 CRK33355.1 - 1.4 8.3 11.3 0.15 11.4 0.4 3.8 2 2 2 4 4 4 0 Protein of unknown function (DUF416) Gp58 PF07902.11 CRK33355.1 - 5.1 5.3 13.4 1.2 7.3 10.2 1.5 2 0 0 2 2 2 0 gp58-like protein UCH PF00443.29 CRK33356.1 - 2.9e-30 105.6 0.0 5.1e-30 104.8 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CRK33356.1 - 9.4e-15 55.0 1.5 5.9e-09 35.9 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 CRK33356.1 - 0.059 12.8 0.7 0.24 10.8 1.0 1.8 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Yos1 PF08571.10 CRK33357.1 - 4e-19 68.7 0.0 6.5e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 Yos1-like Glyco_transf_22 PF03901.17 CRK33358.1 - 7.7e-11 41.9 6.1 1.3e-10 41.1 6.1 1.2 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Zn_clus PF00172.18 CRK33358.1 - 2.2e-07 30.9 9.6 3.5e-07 30.2 9.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 CRK33358.1 - 2e-05 23.6 0.2 0.0004 19.3 0.0 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain BNR PF02012.20 CRK33358.1 - 0.074 13.1 0.1 0.28 11.3 0.0 2.0 2 0 0 2 2 2 0 BNR/Asp-box repeat Glyco_hydro_17 PF00332.18 CRK33359.1 - 3.7e-08 33.3 0.5 9.8e-05 22.1 0.4 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 MFS_1 PF07690.16 CRK33359.1 - 0.015 14.2 0.2 0.015 14.2 0.2 1.8 2 0 0 2 2 2 0 Major Facilitator Superfamily DUF4179 PF13786.6 CRK33359.1 - 0.14 12.7 0.3 0.46 11.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) Pkinase PF00069.25 CRK33360.1 - 5e-16 58.9 0.0 9.2e-10 38.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CRK33360.1 - 5.5e-06 25.8 0.1 0.11 11.7 0.0 2.4 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 CRK33360.1 - 0.0011 19.0 2.1 0.0036 17.2 0.1 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 CRK33360.1 - 0.012 15.0 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CRK33360.1 - 0.11 11.8 0.0 1.3 8.3 0.0 2.0 2 0 0 2 2 2 0 Kinase-like Lipase_GDSL_2 PF13472.6 CRK33361.1 - 2.1e-12 47.8 0.4 3.1e-12 47.3 0.4 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 CRK33361.1 - 0.05 13.6 0.0 0.063 13.3 0.0 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase tRNA-synt_His PF13393.6 CRK33362.1 - 2.4e-38 132.2 0.0 3.8e-38 131.5 0.0 1.3 1 0 0 1 1 1 1 Histidyl-tRNA synthetase Pkinase PF00069.25 CRK33362.1 - 1.1e-19 70.8 0.0 6.4e-12 45.4 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CRK33362.1 - 5.9e-10 38.9 0.2 0.00036 19.9 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase HGTP_anticodon PF03129.20 CRK33362.1 - 7.2e-06 26.1 0.0 1.5e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain APH PF01636.23 CRK33362.1 - 0.0095 15.9 0.1 0.027 14.4 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family tRNA-synt_2 PF00152.20 CRK33362.1 - 0.016 14.3 0.1 0.15 11.1 0.1 2.1 1 1 0 1 1 1 0 tRNA synthetases class II (D, K and N) Kdo PF06293.14 CRK33362.1 - 0.081 12.3 0.0 0.21 10.9 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HGTP_anticodon2 PF12745.7 CRK33362.1 - 0.2 11.1 0.0 0.33 10.4 0.0 1.3 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs Sugar_tr PF00083.24 CRK33363.1 - 6.4e-63 213.2 17.0 7.4e-63 213.0 17.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK33363.1 - 1.6e-15 56.9 24.5 4.3e-10 39.1 6.5 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1593 PF07632.11 CRK33365.1 - 7.2e-90 300.9 0.0 9.9e-90 300.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) REJ PF02010.15 CRK33365.1 - 0.0046 15.8 0.2 0.0079 15.0 0.2 1.4 1 1 0 1 1 1 1 REJ domain CSTF1_dimer PF16699.5 CRK33365.1 - 0.071 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Cleavage stimulation factor subunit 1, dimerisation domain SRR1 PF07985.12 CRK33367.1 - 1e-14 54.3 0.0 1.7e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 SRR1 PUL PF08324.11 CRK33370.1 - 2.1e-73 247.0 0.1 2.9e-73 246.5 0.1 1.2 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 CRK33370.1 - 5e-45 152.4 0.1 8.9e-45 151.6 0.1 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 CRK33370.1 - 5.8e-13 49.1 0.6 2.2e-06 28.3 0.0 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat FA_desaturase PF00487.24 CRK33374.1 - 4e-17 62.9 13.4 4e-17 62.9 13.4 2.0 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 CRK33374.1 - 5e-17 61.8 0.0 1e-16 60.8 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain OMPdecase PF00215.24 CRK33376.1 - 5.1e-59 199.6 0.1 9.4e-59 198.7 0.1 1.4 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Pkinase PF00069.25 CRK33376.1 - 2.6e-17 63.1 0.0 3.1e-09 36.6 0.0 3.9 2 2 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CRK33376.1 - 1.3e-12 47.6 0.0 4.3e-07 29.5 0.0 3.7 2 2 0 2 2 2 2 Protein tyrosine kinase DcpS_C PF11969.8 CRK33376.1 - 0.013 16.0 1.3 22 5.6 0.1 3.4 3 0 0 3 3 3 0 Scavenger mRNA decapping enzyme C-term binding Seadorna_VP7 PF07387.11 CRK33376.1 - 0.014 14.4 0.0 5.4 6.0 0.0 2.3 2 0 0 2 2 2 0 Seadornavirus VP7 Lon_C PF05362.13 CRK33378.1 - 1.1e-63 214.5 0.0 2.1e-63 213.6 0.0 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 CRK33378.1 - 1.1e-32 113.7 0.1 2.9e-32 112.2 0.1 1.7 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 CRK33378.1 - 7.7e-22 78.1 0.0 2.4e-21 76.5 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.6 CRK33378.1 - 1.8e-07 31.1 0.0 4.3e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.14 CRK33378.1 - 9.5e-07 28.9 0.0 2.4e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CRK33378.1 - 1.5e-06 28.5 0.1 5.5e-06 26.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_PrkA PF08298.11 CRK33378.1 - 3e-05 23.1 0.0 6e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain AAA_22 PF13401.6 CRK33378.1 - 3.7e-05 24.0 0.0 0.00058 20.1 0.0 2.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 CRK33378.1 - 8.1e-05 22.4 0.0 0.00065 19.5 0.0 2.5 4 0 0 4 4 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CRK33378.1 - 0.0005 20.5 1.8 0.002 18.6 0.1 2.7 2 1 1 3 3 2 1 AAA ATPase domain AAA_14 PF13173.6 CRK33378.1 - 0.0077 16.3 0.0 0.032 14.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 CRK33378.1 - 0.012 15.4 0.0 0.096 12.4 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_18 PF13238.6 CRK33378.1 - 0.013 16.0 0.4 0.078 13.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 CRK33378.1 - 0.042 13.6 0.0 0.13 11.9 0.0 1.8 2 0 0 2 2 1 0 AAA domain RsgA_GTPase PF03193.16 CRK33378.1 - 0.043 13.7 0.0 0.15 12.0 0.0 1.9 1 0 0 1 1 1 0 RsgA GTPase RNA_helicase PF00910.22 CRK33378.1 - 0.054 13.9 0.0 0.16 12.3 0.0 1.9 1 0 0 1 1 1 0 RNA helicase DNTTIP1_dimer PF18192.1 CRK33378.1 - 0.063 13.6 0.2 1.4 9.3 0.1 2.9 2 0 0 2 2 2 0 DNTTIP1 dimerisation domain NTPase_1 PF03266.15 CRK33378.1 - 0.077 12.9 0.2 1.6 8.6 0.0 2.6 1 1 1 2 2 2 0 NTPase SKI PF01202.22 CRK33378.1 - 0.097 12.8 0.1 0.5 10.5 0.0 2.2 2 0 0 2 2 2 0 Shikimate kinase AAA_3 PF07726.11 CRK33378.1 - 0.099 12.5 0.0 0.81 9.5 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 CRK33378.1 - 0.13 11.8 1.1 0.25 10.8 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region Cytidylate_kin PF02224.18 CRK33378.1 - 0.25 11.0 2.2 6 6.5 0.0 2.7 3 0 0 3 3 3 0 Cytidylate kinase ABC_tran PF00005.27 CRK33378.1 - 0.8 10.2 3.9 0.87 10.1 0.1 2.7 3 0 0 3 3 2 0 ABC transporter ClpB_D2-small PF10431.9 CRK33378.1 - 0.93 9.6 7.1 0.13 12.3 0.4 2.8 3 0 0 3 3 2 0 C-terminal, D2-small domain, of ClpB protein MSA-2c PF12238.8 CRK33379.1 - 8.5 6.3 8.3 12 5.8 8.3 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c eIF3_subunit PF08597.10 CRK33381.1 - 0.72 9.7 14.9 0.77 9.6 0.3 2.1 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit MSA-2c PF12238.8 CRK33381.1 - 4.1 7.4 8.7 6.3 6.7 8.7 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c GST_C_3 PF14497.6 CRK33383.1 - 3.8e-32 110.4 0.8 5e-15 55.5 0.1 2.3 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CRK33383.1 - 6.9e-31 106.3 2.5 1.7e-14 53.8 0.2 2.2 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CRK33383.1 - 1.1e-18 67.0 0.0 7.5e-08 32.3 0.0 2.6 2 0 0 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CRK33383.1 - 4e-17 62.4 0.1 4.7e-07 30.1 0.0 2.5 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 CRK33383.1 - 9.1e-14 51.6 0.1 1.9e-05 24.9 0.0 2.8 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CRK33383.1 - 1.1e-13 51.3 0.6 1.9e-05 24.9 0.1 2.6 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 CRK33383.1 - 5.1e-07 29.4 0.0 0.038 13.8 0.0 3.0 2 1 0 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 CRK33383.1 - 1.5e-06 28.9 0.2 0.11 13.3 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase N-terminal domain DUF4130 PF13566.6 CRK33383.1 - 0.0029 17.6 0.2 1.9 8.5 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4130 ICAT PF06384.11 CRK33383.1 - 0.012 15.9 0.1 8.5 6.7 0.0 2.4 2 0 0 2 2 2 0 Beta-catenin-interacting protein ICAT DUF4125 PF13526.6 CRK33383.1 - 0.03 14.0 0.3 4.9 6.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4125) SCAPER_N PF16501.5 CRK33383.1 - 0.052 13.6 1.0 6.7 6.8 0.1 2.3 2 0 0 2 2 2 0 S phase cyclin A-associated protein in the endoplasmic reticulum G-alpha PF00503.20 CRK33385.1 - 1.8e-114 382.6 0.7 2e-114 382.4 0.7 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CRK33385.1 - 1.4e-15 57.2 0.1 3.2e-10 39.8 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CRK33385.1 - 0.00014 21.3 0.4 0.084 12.2 0.2 2.3 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 CRK33385.1 - 0.0039 17.4 0.4 1.3 9.3 0.1 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase NitrOD2 PF18550.1 CRK33385.1 - 0.052 13.7 0.0 0.58 10.3 0.0 2.4 1 1 1 2 2 2 0 Nitrososphaera output domain 2 AAA_29 PF13555.6 CRK33385.1 - 0.1 12.4 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.20 CRK33386.1 - 6.7e-88 295.2 0.7 7.7e-88 295.0 0.7 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CRK33386.1 - 2.1e-10 40.3 0.1 5.1e-10 39.1 0.1 1.6 1 0 0 1 1 1 1 ADP-ribosylation factor family NitrOD2 PF18550.1 CRK33386.1 - 0.088 13.0 0.0 0.8 9.9 0.0 2.4 1 1 1 2 2 2 0 Nitrososphaera output domain 2 Phosphorylase PF00343.20 CRK33387.1 - 1.6e-274 912.6 1.8 1.4e-146 489.7 0.6 2.0 1 1 1 2 2 2 2 Carbohydrate phosphorylase Pkinase PF00069.25 CRK33388.1 - 2.1e-55 188.0 0.0 1.3e-31 109.9 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CRK33388.1 - 6.8e-22 78.0 0.2 5.5e-19 68.5 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Avl9 PF09794.9 CRK33388.1 - 1.2e-14 53.8 0.1 1.7e-14 53.3 0.1 1.2 1 0 0 1 1 1 1 Transport protein Avl9 Kdo PF06293.14 CRK33388.1 - 0.0005 19.5 0.0 0.0015 17.9 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TAF4 PF05236.14 CRK33388.1 - 0.023 14.5 2.5 0.034 13.9 2.5 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family DUF3679 PF12438.8 CRK33389.1 - 0.061 13.0 0.1 0.25 11.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3679) FRG2 PF15315.6 CRK33390.1 - 1.1 9.5 20.4 1.4 9.1 20.4 1.1 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 PI3_PI4_kinase PF00454.27 CRK33391.1 - 6.7e-45 153.9 0.0 8.9e-45 153.4 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Methyltransf_23 PF13489.6 CRK33392.1 - 8.6e-12 45.2 0.0 1.3e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK33392.1 - 3.9e-10 40.3 0.0 8.4e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CRK33392.1 - 4.3e-06 27.3 0.0 7.9e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK33392.1 - 0.00015 21.6 0.0 0.00058 19.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK33392.1 - 0.00015 22.5 0.0 0.00027 21.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 CRK33392.1 - 0.0014 18.1 0.0 0.0029 17.1 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_2 PF00891.18 CRK33392.1 - 0.028 13.7 0.0 0.043 13.1 0.0 1.5 1 1 0 1 1 1 0 O-methyltransferase domain Methyltransf_16 PF10294.9 CRK33392.1 - 0.15 11.7 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase Ubie_methyltran PF01209.18 CRK33392.1 - 0.19 11.1 0.0 0.32 10.3 0.0 1.4 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family GCP_N_terminal PF17681.1 CRK33394.1 - 5.6e-62 210.1 0.0 1.1e-61 209.2 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 CRK33394.1 - 1.1e-58 199.1 3.8 1.1e-58 199.1 3.8 1.9 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal Proteasome PF00227.26 CRK33395.1 - 9.1e-56 188.4 0.2 1.2e-55 188.0 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CRK33395.1 - 1.3e-12 47.2 0.0 3.6e-12 45.7 0.0 1.9 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Fungal_trans_2 PF11951.8 CRK33396.1 - 1.1e-17 63.9 1.2 1.4e-10 40.6 0.4 3.1 3 0 0 3 3 3 3 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK33396.1 - 2.2e-07 30.9 12.2 3.6e-07 30.2 12.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Asp_protease PF09668.10 CRK33398.1 - 1.2e-60 202.8 0.6 1.6e-60 202.4 0.6 1.2 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CRK33398.1 - 5.5e-24 84.5 0.1 9e-24 83.9 0.1 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CRK33398.1 - 2e-11 44.4 0.1 3.3e-11 43.7 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease UBA PF00627.31 CRK33398.1 - 1.8e-07 30.9 0.1 3.2e-07 30.1 0.1 1.5 1 0 0 1 1 1 1 UBA/TS-N domain RVP_2 PF08284.11 CRK33398.1 - 1.3e-05 25.0 0.0 2.3e-05 24.2 0.0 1.4 1 1 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.20 CRK33398.1 - 6.1e-05 23.3 0.1 0.00016 21.9 0.1 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease DUF3577 PF12101.8 CRK33398.1 - 0.0086 15.9 0.1 0.36 10.6 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3577) UBA_4 PF14555.6 CRK33398.1 - 0.4 10.5 2.5 0.5 10.2 0.6 2.1 2 1 1 3 3 3 0 UBA-like domain Acetyltransf_1 PF00583.25 CRK33399.1 - 2.3e-08 34.3 0.0 4.4e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CRK33399.1 - 5.7e-08 32.8 0.0 9.9e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CRK33399.1 - 1.2e-06 28.8 0.0 1.8e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GDI PF00996.18 CRK33400.1 - 2e-139 464.8 0.0 3.9e-139 463.9 0.0 1.4 1 0 0 1 1 1 1 GDP dissociation inhibitor NOG1_N PF17835.1 CRK33400.1 - 8.3e-47 159.1 0.0 2.5e-46 157.6 0.0 1.9 1 0 0 1 1 1 1 NOG1 N-terminal helical domain NOGCT PF08155.11 CRK33400.1 - 8.4e-29 99.3 0.8 2e-28 98.1 0.8 1.7 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.14 CRK33400.1 - 5.9e-26 90.0 0.2 1.5e-25 88.7 0.2 1.8 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 CRK33400.1 - 9.3e-14 51.5 0.0 2.1e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CRK33400.1 - 1.2e-08 34.6 0.0 2.2e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CRK33400.1 - 0.0037 17.2 0.1 0.7 9.8 0.2 2.8 2 0 0 2 2 2 1 RsgA GTPase GDI PF00996.18 CRK33402.1 - 2e-255 847.1 0.0 2.3e-195 649.2 0.0 2.0 2 0 0 2 2 2 2 GDP dissociation inhibitor NAD_binding_8 PF13450.6 CRK33402.1 - 1.6e-06 28.2 0.1 0.12 12.6 0.0 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 CRK33402.1 - 0.00012 22.6 1.2 0.96 10.1 0.1 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CRK33402.1 - 0.0014 17.9 0.3 1.8 7.7 0.0 2.5 2 0 0 2 2 2 2 FAD binding domain Carb_kinase PF01256.17 CRK33402.1 - 0.059 12.8 0.0 2.3 7.6 0.0 2.2 2 0 0 2 2 2 0 Carbohydrate kinase Pyr_redox_2 PF07992.14 CRK33402.1 - 0.074 12.3 0.4 3.8 6.6 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MRP-L47 PF06984.13 CRK33403.1 - 1.8e-20 72.9 0.3 2.9e-20 72.2 0.3 1.4 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Clc-like PF07062.12 CRK33403.1 - 0.34 10.3 0.8 0.54 9.7 0.8 1.3 1 0 0 1 1 1 0 Clc-like zf-H2C2_2 PF13465.6 CRK33404.1 - 8.6e-07 29.1 6.6 1.8e-05 25.0 1.1 2.7 2 0 0 2 2 2 2 Zinc-finger double domain Fungal_trans PF04082.18 CRK33404.1 - 0.00025 20.2 0.2 0.00041 19.4 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-Di19 PF05605.12 CRK33404.1 - 0.00057 20.1 4.4 0.0015 18.8 4.4 1.7 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 CRK33404.1 - 0.0013 19.4 15.1 0.061 14.2 5.8 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CRK33404.1 - 0.19 12.1 3.1 8.5 6.8 0.8 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 CRK33404.1 - 0.35 11.4 14.6 0.36 11.4 7.3 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type Actin PF00022.19 CRK33407.1 - 1.4e-16 60.1 0.0 4.2e-13 48.7 0.0 3.0 3 0 0 3 3 3 2 Actin MreB_Mbl PF06723.13 CRK33407.1 - 0.008 15.0 0.0 0.2 10.4 0.0 2.3 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 CRK33407.1 - 0.038 14.4 0.0 0.12 12.9 0.0 1.9 1 1 0 1 1 1 0 Cell division protein FtsA Ysc84 PF04366.12 CRK33408.1 - 5.1e-29 100.6 0.0 8.6e-29 99.9 0.0 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator TFIIA PF03153.13 CRK33408.1 - 0.005 16.9 7.9 0.011 15.8 7.9 1.5 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Cwf_Cwc_15 PF04889.12 CRK33408.1 - 0.92 9.2 11.5 1.8 8.2 11.5 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CENP-B_dimeris PF09026.10 CRK33408.1 - 6.4 7.2 13.1 0.36 11.2 7.6 1.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Ribonuc_L-PSP PF01042.21 CRK33409.1 - 5.3e-27 94.2 0.0 5.9e-27 94.1 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP zf-RING_2 PF13639.6 CRK33410.1 - 6.6e-05 23.2 9.2 0.00014 22.1 9.2 1.6 1 0 0 1 1 1 1 Ring finger domain Prok-RING_1 PF14446.6 CRK33410.1 - 0.00016 21.5 7.5 0.0004 20.3 7.5 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 zf-C3HC4_2 PF13923.6 CRK33410.1 - 0.05 13.5 3.4 0.13 12.2 3.4 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 CRK33410.1 - 0.084 12.8 10.8 0.19 11.7 10.8 1.6 1 0 0 1 1 1 0 PHD-finger Zn_ribbon_17 PF17120.5 CRK33410.1 - 0.2 11.3 7.9 0.41 10.3 7.9 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type C1_1 PF00130.22 CRK33410.1 - 1.2 9.1 11.9 0.088 12.7 6.0 2.1 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Ribonuc_L-PSP PF01042.21 CRK33411.1 - 5.3e-27 94.2 0.0 5.9e-27 94.1 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Sulf_transp PF04143.14 CRK33412.1 - 6.4e-38 131.1 39.8 7.4e-24 84.9 24.0 2.6 1 1 2 3 3 3 2 Sulphur transport DUF4149 PF13664.6 CRK33412.1 - 0.29 11.5 8.8 3.8 7.9 0.3 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4149) Adeno_PIX PF03955.14 CRK33412.1 - 0.51 10.5 4.8 2.8 8.2 0.0 3.3 2 1 1 3 3 3 0 Adenovirus hexon-associated protein (IX) ADH_zinc_N PF00107.26 CRK33413.1 - 4.2e-20 72.0 0.4 6.8e-20 71.4 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CRK33413.1 - 3.2e-08 34.7 0.1 8.3e-08 33.4 0.1 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CRK33413.1 - 0.055 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 CRK33413.1 - 0.069 12.6 0.2 0.1 12.0 0.2 1.3 1 0 0 1 1 1 0 short chain dehydrogenase KH_8 PF17903.1 CRK33414.1 - 2.4e-30 104.4 0.0 4.5e-30 103.6 0.0 1.5 1 0 0 1 1 1 1 Krr1 KH1 domain GATA PF00320.27 CRK33415.1 - 1.5e-15 56.5 1.6 2.2e-15 56.0 1.6 1.3 1 0 0 1 1 1 1 GATA zinc finger ADH_zinc_N PF00107.26 CRK33415.1 - 3.1e-12 46.6 0.0 4.5e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CRK33415.1 - 8.8e-09 36.5 0.0 1.1e-08 36.1 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TF_Zn_Ribbon PF08271.12 CRK33415.1 - 0.065 12.8 1.1 0.14 11.7 1.1 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding ArfGap PF01412.18 CRK33415.1 - 0.11 12.6 0.2 0.19 11.8 0.2 1.4 1 1 0 1 1 1 0 Putative GTPase activating protein for Arf OTT_1508_deam PF14441.6 CRK33415.1 - 0.17 11.9 0.2 4.3 7.4 0.0 2.2 2 0 0 2 2 2 0 OTT_1508-like deaminase Auto_anti-p27 PF06677.12 CRK33415.1 - 0.52 10.5 3.2 0.3 11.3 0.9 1.9 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) ADH_N PF08240.12 CRK33417.1 - 0.038 13.9 0.0 0.054 13.4 0.0 1.3 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain GATA PF00320.27 CRK33418.1 - 4.9e-15 54.8 1.6 8.1e-15 54.1 1.6 1.4 1 0 0 1 1 1 1 GATA zinc finger CDC45 PF02724.14 CRK33418.1 - 0.029 12.7 7.4 0.048 12.0 7.4 1.4 1 0 0 1 1 1 0 CDC45-like protein Ndc1_Nup PF09531.10 CRK33418.1 - 0.034 12.8 11.2 0.048 12.3 11.2 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup NodZ PF05830.11 CRK33418.1 - 0.04 12.7 0.0 0.068 12.0 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein Z (NodZ) PA26 PF04636.13 CRK33418.1 - 0.21 10.5 9.4 0.44 9.4 9.4 1.5 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) TF_Zn_Ribbon PF08271.12 CRK33418.1 - 0.26 10.8 1.1 0.49 10.0 1.1 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding FAM60A PF15396.6 CRK33418.1 - 2.5 8.1 17.6 28 4.6 13.7 2.5 2 0 0 2 2 2 0 Protein Family FAM60A Pet20 PF08692.10 CRK33418.1 - 2.5 8.8 13.9 23 5.7 7.7 2.8 3 0 0 3 3 3 0 Mitochondrial protein Pet20 Membralin PF09746.9 CRK33418.1 - 7.7 5.4 7.9 15 4.5 7.9 1.4 1 0 0 1 1 1 0 Tumour-associated protein Endostatin PF06482.11 CRK33418.1 - 8.6 5.7 21.1 28 4.0 19.6 2.1 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin Hid1 PF12722.7 CRK33418.1 - 8.8 4.3 18.0 18 3.3 18.0 1.4 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Mit_KHE1 PF10173.9 CRK33420.1 - 3.6e-66 222.9 0.1 3.6e-66 222.9 0.1 1.6 2 0 0 2 2 2 1 Mitochondrial K+-H+ exchange-related DUF4203 PF13886.6 CRK33421.1 - 0.04 13.6 1.3 0.077 12.7 1.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) AtuA PF07287.11 CRK33422.1 - 7.1e-133 442.7 1.8 8.8e-133 442.4 1.8 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA DUF2034 PF10356.9 CRK33422.1 - 3.1e-29 101.7 0.0 1.1e-26 93.5 0.0 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 CRK33422.1 - 2.2e-06 27.7 0.0 5e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Restriction endonuclease GTP_EFTU PF00009.27 CRK33423.1 - 1.1e-52 178.4 0.0 2e-52 177.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 CRK33423.1 - 1.3e-18 66.8 0.0 3.3e-18 65.5 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 CRK33423.1 - 0.00033 21.0 0.1 0.0026 18.1 0.0 2.6 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CRK33423.1 - 0.024 14.7 0.0 0.063 13.4 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF5632 PF18646.1 CRK33423.1 - 0.11 12.6 0.6 0.28 11.3 0.1 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5632) TALPID3 PF15324.6 CRK33423.1 - 3.1 5.3 22.7 4.4 4.8 22.7 1.1 1 0 0 1 1 1 0 Hedgehog signalling target DUF4366 PF14283.6 CRK33423.1 - 9.2 6.3 10.8 17 5.4 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4366) Thiolase_N PF00108.23 CRK33424.1 - 2.3e-86 289.4 0.7 5e-86 288.3 0.7 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CRK33424.1 - 1.5e-37 127.9 0.7 4.4e-37 126.5 0.7 1.8 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 CRK33424.1 - 9.2e-05 22.1 0.1 0.00023 20.9 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PCI PF01399.27 CRK33424.1 - 0.00027 21.4 0.0 0.37 11.3 0.0 2.6 2 0 0 2 2 2 2 PCI domain Kinesin PF00225.23 CRK33425.1 - 5.1e-113 377.4 0.5 1.1e-112 376.2 0.5 1.6 1 0 0 1 1 1 1 Kinesin motor domain UQ_con PF00179.26 CRK33425.1 - 2.6e-49 166.5 0.0 5.7e-49 165.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Microtub_bd PF16796.5 CRK33425.1 - 5.2e-27 94.6 0.1 1.7e-26 92.9 0.1 2.0 1 0 0 1 1 1 1 Microtubule binding Prok-E2_B PF14461.6 CRK33425.1 - 0.0049 16.6 0.0 0.035 13.8 0.0 2.4 2 0 0 2 2 2 1 Prokaryotic E2 family B HALZ PF02183.18 CRK33425.1 - 0.58 10.4 16.6 5.1 7.4 1.0 5.7 5 0 0 5 5 5 0 Homeobox associated leucine zipper DUF3349 PF11829.8 CRK33425.1 - 1 10.1 7.0 0.38 11.5 0.6 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) HAP1_N PF04849.13 CRK33425.1 - 7.8 5.6 51.7 0.3 10.3 18.1 3.5 3 0 0 3 3 3 0 HAP1 N-terminal conserved region BAR_2 PF10455.9 CRK33427.1 - 3.2e-59 200.5 0.5 4.7e-59 199.9 0.5 1.3 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking ETC_C1_NDUFA5 PF04716.14 CRK33427.1 - 6.2e-23 80.4 0.0 6.2e-23 80.4 0.0 3.8 4 0 0 4 4 4 1 ETC complex I subunit conserved region BAR PF03114.18 CRK33427.1 - 3e-21 76.2 4.4 6.7e-20 71.8 4.4 2.2 1 1 0 1 1 1 1 BAR domain BAR_3 PF16746.5 CRK33427.1 - 0.032 13.9 0.7 0.076 12.7 0.3 1.9 2 0 0 2 2 2 0 BAR domain of APPL family ATP_synt_H PF05493.13 CRK33428.1 - 7e-25 87.3 0.9 7.8e-25 87.1 0.9 1.0 1 0 0 1 1 1 1 ATP synthase subunit H DUF2079 PF09852.9 CRK33428.1 - 0.0064 15.4 0.6 0.0073 15.2 0.6 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2079) Git3 PF11710.8 CRK33428.1 - 0.023 14.5 0.1 0.024 14.4 0.1 1.1 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 DUF1129 PF06570.11 CRK33428.1 - 0.06 12.8 0.2 0.076 12.5 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) YfhO PF09586.10 CRK33428.1 - 0.15 10.3 0.2 0.16 10.2 0.2 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF4131 PF13567.6 CRK33428.1 - 0.21 11.2 1.4 0.22 11.1 1.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Arv1 PF04161.13 CRK33429.1 - 5.4e-77 258.7 1.2 6.5e-77 258.4 1.2 1.1 1 0 0 1 1 1 1 Arv1-like family MerT PF02411.15 CRK33429.1 - 0.14 12.2 2.9 0.3 11.1 0.1 2.2 2 0 0 2 2 2 0 MerT mercuric transport protein Shugoshin_N PF07558.11 CRK33430.1 - 0.083 12.8 0.1 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region Fmp27_WPPW PF10359.9 CRK33430.1 - 0.18 10.6 0.7 0.25 10.1 0.7 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain CENP-F_leu_zip PF10473.9 CRK33430.1 - 3.5 7.6 12.5 0.92 9.5 2.0 2.5 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 CRK33430.1 - 8.4 6.6 14.1 0.27 11.5 5.7 2.4 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Mit_KHE1 PF10173.9 CRK33431.1 - 5.1e-66 222.4 0.1 5.1e-66 222.4 0.1 1.4 2 0 0 2 2 2 1 Mitochondrial K+-H+ exchange-related Cullin PF00888.22 CRK33432.1 - 1.5e-188 628.3 11.5 2.1e-188 627.8 11.5 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 CRK33432.1 - 2.1e-25 88.5 5.4 2.1e-25 88.5 5.4 2.4 3 0 0 3 3 3 1 Cullin protein neddylation domain WAC_Acf1_DNA_bd PF10537.9 CRK33432.1 - 0.063 13.8 5.2 0.12 12.9 0.6 3.3 3 0 0 3 3 3 0 ATP-utilising chromatin assembly and remodelling N-terminal AtuA PF07287.11 CRK33433.1 - 1.5e-132 441.6 1.8 1.9e-132 441.3 1.8 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA DUF2034 PF10356.9 CRK33433.1 - 3.5e-29 101.5 0.0 1.3e-26 93.2 0.0 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 CRK33433.1 - 2.1e-06 27.7 0.0 4.8e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Restriction endonuclease GTP_EFTU PF00009.27 CRK33434.1 - 6.6e-52 175.9 0.0 1.2e-51 175.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 CRK33434.1 - 2.1e-18 66.2 0.0 4.9e-18 65.0 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 CRK33434.1 - 3e-13 49.6 0.0 1.2e-05 25.3 0.0 3.2 3 0 0 3 3 3 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 CRK33434.1 - 4.3e-05 23.8 0.0 0.00055 20.3 0.0 2.8 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CRK33434.1 - 0.04 14.0 0.0 0.11 12.6 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase Cupin_1 PF00190.22 CRK33435.1 - 3.1e-16 59.3 0.1 5.3e-16 58.6 0.1 1.3 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 CRK33435.1 - 0.047 13.4 0.0 0.094 12.4 0.0 1.7 1 1 0 1 1 1 0 Cupin domain EFG_C PF00679.24 CRK33436.1 - 3.3e-11 43.1 0.0 5e-07 29.7 0.0 2.1 2 0 0 2 2 2 2 Elongation factor G C-terminus Cupin_1 PF00190.22 CRK33437.1 - 2.8e-16 59.5 0.2 5.3e-16 58.6 0.1 1.5 2 0 0 2 2 2 1 Cupin Cupin_2 PF07883.11 CRK33437.1 - 0.047 13.4 0.0 0.094 12.4 0.0 1.6 1 1 0 1 1 1 0 Cupin domain SUN PF03856.13 CRK33438.1 - 1.3e-71 241.0 13.6 1.7e-71 240.6 13.6 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) RPN2_C PF18004.1 CRK33438.1 - 0.18 11.8 5.9 0.9 9.4 5.3 2.2 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain Nop14 PF04147.12 CRK33438.1 - 0.19 9.9 11.6 0.28 9.4 11.6 1.1 1 0 0 1 1 1 0 Nop14-like family RXT2_N PF08595.11 CRK33438.1 - 0.3 11.1 5.6 0.6 10.1 5.6 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.12 CRK33438.1 - 1.4 8.2 20.3 2.6 7.3 20.3 1.4 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 CRK33438.1 - 1.4 9.3 22.0 5.4 7.5 22.0 2.0 1 0 0 1 1 1 0 Centromere protein B dimerisation domain CDC45 PF02724.14 CRK33438.1 - 2.4 6.4 11.8 3.8 5.7 11.8 1.2 1 0 0 1 1 1 0 CDC45-like protein TFB6 PF17110.5 CRK33438.1 - 2.6 7.8 5.2 5.6 6.7 5.2 1.5 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Sigma70_ner PF04546.13 CRK33438.1 - 3.3 7.6 11.9 5.7 6.8 11.9 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region TALPID3 PF15324.6 CRK33438.1 - 4.9 4.7 23.7 7.7 4.0 23.7 1.2 1 0 0 1 1 1 0 Hedgehog signalling target Thiolase_N PF00108.23 CRK33439.1 - 2.8e-86 289.1 0.9 5.8e-86 288.1 0.9 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CRK33439.1 - 1.7e-37 127.8 0.7 4.6e-37 126.4 0.7 1.8 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 CRK33439.1 - 0.0001 22.0 0.2 0.00024 20.8 0.2 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PCI PF01399.27 CRK33439.1 - 0.0028 18.1 0.0 0.69 10.5 0.0 2.6 2 0 0 2 2 2 2 PCI domain UQ_con PF00179.26 CRK33440.1 - 5.4e-52 175.2 0.1 6.1e-52 175.0 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CRK33440.1 - 0.00062 19.5 0.0 0.00069 19.3 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 CRK33440.1 - 0.036 14.4 0.0 0.048 14.0 0.0 1.4 1 1 0 1 1 1 0 RWD domain Kinesin PF00225.23 CRK33441.1 - 3.5e-113 377.9 0.5 8.4e-113 376.7 0.5 1.7 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CRK33441.1 - 5.5e-27 94.5 0.1 2.1e-26 92.7 0.1 2.1 1 0 0 1 1 1 1 Microtubule binding HALZ PF02183.18 CRK33441.1 - 0.28 11.4 16.5 4.3 7.6 1.0 5.8 6 0 0 6 6 6 0 Homeobox associated leucine zipper DUF3349 PF11829.8 CRK33441.1 - 1 10.2 6.9 0.48 11.2 0.5 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) HAP1_N PF04849.13 CRK33441.1 - 8.1 5.5 51.7 0.24 10.6 18.1 3.5 3 0 0 3 3 3 0 HAP1 N-terminal conserved region Glft2_N PF17994.1 CRK33442.1 - 0.13 12.2 0.8 0.31 11.0 0.1 1.8 2 0 0 2 2 2 0 Galactofuranosyltransferase 2 N-terminal DUF4349 PF14257.6 CRK33442.1 - 2.3 7.6 12.6 0.9 8.9 1.7 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4349) BAR_2 PF10455.9 CRK33443.1 - 3.3e-59 200.4 0.5 4.9e-59 199.8 0.5 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking ETC_C1_NDUFA5 PF04716.14 CRK33443.1 - 6.4e-23 80.3 0.0 6.4e-23 80.3 0.0 3.2 4 0 0 4 4 4 1 ETC complex I subunit conserved region BAR PF03114.18 CRK33443.1 - 3.2e-21 76.1 4.4 6.9e-20 71.7 4.4 2.2 1 1 0 1 1 1 1 BAR domain BAR_3 PF16746.5 CRK33443.1 - 0.03 14.0 0.9 0.069 12.9 0.4 1.8 2 0 0 2 2 2 0 BAR domain of APPL family NAT PF04768.13 CRK33444.1 - 1e-49 168.5 0.0 2e-49 167.5 0.0 1.4 1 0 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase ATP_synt_H PF05493.13 CRK33445.1 - 7.7e-25 87.1 0.9 8.7e-25 87.0 0.9 1.0 1 0 0 1 1 1 1 ATP synthase subunit H DUF2079 PF09852.9 CRK33445.1 - 0.0089 14.9 0.8 0.01 14.7 0.8 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2079) Git3 PF11710.8 CRK33445.1 - 0.02 14.6 0.1 0.022 14.5 0.1 1.0 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 DUF1129 PF06570.11 CRK33445.1 - 0.048 13.1 0.2 0.059 12.9 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Arv1 PF04161.13 CRK33446.1 - 4.3e-79 265.5 0.5 5.1e-79 265.3 0.5 1.0 1 0 0 1 1 1 1 Arv1-like family MerT PF02411.15 CRK33446.1 - 0.29 11.2 3.4 0.47 10.5 0.1 2.2 2 0 0 2 2 2 0 MerT mercuric transport protein LysM PF01476.20 CRK33447.1 - 0.066 13.3 0.0 0.25 11.4 0.0 1.9 2 0 0 2 2 2 0 LysM domain LysM PF01476.20 CRK33448.1 - 0.17 12.0 0.0 0.34 11.0 0.0 1.4 1 0 0 1 1 1 0 LysM domain PigN PF04987.14 CRK33449.1 - 2e-87 294.0 12.6 2e-87 294.0 12.6 2.1 2 0 0 2 2 2 1 Phosphatidylinositolglycan class N (PIG-N) Fungal_trans PF04082.18 CRK33449.1 - 2.8e-38 131.5 0.2 1.5e-37 129.1 0.0 2.2 3 0 0 3 3 3 1 Fungal specific transcription factor domain Csm1 PF12539.8 CRK33449.1 - 2.1e-33 114.8 0.1 4.4e-33 113.7 0.1 1.6 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 Phosphodiest PF01663.22 CRK33449.1 - 3e-08 33.6 2.7 1.2e-06 28.4 2.7 2.3 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 CRK33449.1 - 6.1e-08 32.4 0.1 1e-07 31.7 0.1 1.3 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 CRK33449.1 - 6.5e-05 22.4 0.0 0.00012 21.6 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Zn_clus PF00172.18 CRK33449.1 - 0.0023 18.0 1.0 0.004 17.2 1.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain OEP PF02321.18 CRK33449.1 - 0.0066 16.3 7.5 0.017 14.9 7.5 1.7 1 0 0 1 1 1 1 Outer membrane efflux protein CCDC158 PF15921.5 CRK33449.1 - 0.02 12.8 3.6 0.029 12.2 3.6 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 158 XhlA PF10779.9 CRK33449.1 - 0.076 13.2 3.6 0.099 12.9 0.7 2.6 1 1 1 2 2 2 0 Haemolysin XhlA AT_hook PF02178.19 CRK33449.1 - 0.91 9.6 10.2 1.4 9.0 5.0 2.8 2 0 0 2 2 2 0 AT hook motif Cys_Met_Meta_PP PF01053.20 CRK33450.1 - 5.6e-170 565.0 0.2 5.6e-135 449.8 0.0 2.0 1 1 1 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 CRK33450.1 - 8.3e-10 38.4 0.0 2e-06 27.2 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 CRK33450.1 - 4.2e-08 32.9 0.1 0.0078 15.6 0.0 2.7 3 0 0 3 3 3 2 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 CRK33450.1 - 5.3e-06 25.6 0.1 1.7e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class-V DEDD_Tnp_IS110 PF01548.17 CRK33450.1 - 1.7e-05 24.7 0.0 0.69 9.8 0.0 3.2 3 0 0 3 3 3 2 Transposase Met_gamma_lyase PF06838.11 CRK33450.1 - 2e-05 23.3 1.2 0.00076 18.1 0.2 2.6 1 1 0 2 2 2 1 Methionine gamma-lyase MSP PF01716.18 CRK33450.1 - 0.0003 20.1 0.2 0.33 10.1 0.0 2.2 2 0 0 2 2 2 2 Manganese-stabilising protein / photosystem II polypeptide Beta_elim_lyase PF01212.21 CRK33450.1 - 0.00037 19.9 0.2 0.63 9.3 0.0 2.8 2 1 1 3 3 3 2 Beta-eliminating lyase NIR_SIR_ferr PF03460.17 CRK33450.1 - 0.017 15.0 0.3 10 6.1 0.0 2.7 3 0 0 3 3 3 0 Nitrite/Sulfite reductase ferredoxin-like half domain NHase_beta PF02211.15 CRK33450.1 - 0.083 12.9 0.3 16 5.5 0.0 2.2 2 0 0 2 2 2 0 Nitrile hydratase beta subunit DUF4956 PF16316.5 CRK33450.1 - 0.17 11.5 0.3 24 4.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4956) Pantoate_transf PF02548.15 CRK33450.1 - 0.22 10.9 1.8 2.2 7.6 0.5 2.4 2 0 0 2 2 2 0 Ketopantoate hydroxymethyltransferase Serinc PF03348.15 CRK33451.1 - 4.7e-162 539.8 9.9 5.4e-162 539.6 9.9 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) Cation_efflux PF01545.21 CRK33451.1 - 0.0051 16.6 3.1 0.0051 16.6 3.1 3.0 4 0 0 4 4 4 1 Cation efflux family DUF809 PF05663.11 CRK33451.1 - 0.2 11.8 0.2 0.53 10.4 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF809) MFS_1 PF07690.16 CRK33452.1 - 1e-20 74.0 28.5 2.6e-15 56.2 12.6 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily Nodulin-like PF06813.13 CRK33452.1 - 1e-10 41.5 1.6 2.6e-10 40.2 1.6 1.6 1 0 0 1 1 1 1 Nodulin-like PGAP1 PF07819.13 CRK33453.1 - 3.2e-58 197.2 0.0 3.7e-58 197.0 0.0 1.0 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 CRK33453.1 - 0.0012 19.5 0.0 0.0015 19.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 CRK33453.1 - 0.0013 18.7 0.0 0.0015 18.4 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Hydrolase_4 PF12146.8 CRK33453.1 - 0.0018 17.6 0.0 0.003 16.9 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CRK33453.1 - 0.0022 17.7 0.3 0.0065 16.2 0.3 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF676 PF05057.14 CRK33453.1 - 0.0037 16.8 0.1 0.0054 16.3 0.1 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) LCAT PF02450.15 CRK33453.1 - 0.0052 16.0 0.0 0.008 15.4 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_5 PF12695.7 CRK33453.1 - 0.043 13.6 0.0 0.061 13.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF915 PF06028.11 CRK33453.1 - 0.098 12.0 0.0 1.5 8.1 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) COesterase PF00135.28 CRK33453.1 - 0.17 10.7 0.1 0.23 10.3 0.1 1.1 1 0 0 1 1 1 0 Carboxylesterase family DNA_mis_repair PF01119.19 CRK33454.1 - 8.3e-19 67.4 0.0 2.1e-18 66.1 0.0 1.7 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 CRK33454.1 - 2.2e-13 50.2 0.0 5.8e-13 48.8 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CRK33454.1 - 9.4e-07 29.3 0.0 2.2e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase P68HR PF08061.11 CRK33455.1 - 0.039 14.1 0.7 0.096 12.8 0.7 1.6 1 0 0 1 1 1 0 P68HR (NUC004) repeat Pyr_redox_2 PF07992.14 CRK33456.1 - 3e-08 33.3 0.0 7.4e-06 25.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CRK33456.1 - 0.015 15.5 0.0 0.037 14.3 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ETF PF01012.21 CRK33457.1 - 2e-41 141.9 2.8 3.2e-41 141.2 2.8 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 CRK33457.1 - 2.1e-33 114.2 0.7 4.5e-33 113.1 0.7 1.6 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain Carn_acyltransf PF00755.20 CRK33458.1 - 5.6e-207 689.0 0.0 7.7e-207 688.5 0.0 1.2 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase SWIRM PF04433.17 CRK33458.1 - 3.7e-31 107.3 0.1 1.1e-30 105.8 0.1 1.9 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 CRK33458.1 - 2.6e-29 101.0 5.6 6.5e-29 99.7 5.6 1.7 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 CRK33458.1 - 4.2e-10 39.7 0.3 1.3e-09 38.0 0.1 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CRK33458.1 - 2.3e-05 24.5 0.1 6.4e-05 23.1 0.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain PfkB PF00294.24 CRK33459.1 - 8.7e-15 54.8 0.0 9.4e-09 35.0 0.1 2.2 2 0 0 2 2 2 2 pfkB family carbohydrate kinase MCM PF00493.23 CRK33460.1 - 5.7e-66 221.8 0.8 7.1e-37 126.7 0.1 2.6 1 1 1 2 2 2 2 MCM P-loop domain MCM_OB PF17207.3 CRK33460.1 - 9.5e-31 106.3 0.0 1.8e-30 105.4 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CRK33460.1 - 3e-24 85.2 0.3 8.3e-24 83.8 0.3 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CRK33460.1 - 6.7e-13 49.1 0.0 2.2e-12 47.5 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 CRK33460.1 - 0.016 14.6 0.0 0.23 10.8 0.0 2.3 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI Aminotran_3 PF00202.21 CRK33461.1 - 1.1e-26 93.5 0.1 1.2e-26 93.3 0.1 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Sugar_tr PF00083.24 CRK33463.1 - 8.4e-11 41.4 1.5 5.6e-06 25.5 0.9 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CRK33463.1 - 0.0026 16.7 1.7 0.0067 15.4 1.1 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK33464.1 - 7.2e-10 38.3 1.6 8.3e-10 38.1 1.6 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter ADH_zinc_N PF00107.26 CRK33465.1 - 1.1e-20 73.9 0.0 1.9e-20 73.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CRK33465.1 - 9.8e-11 42.8 0.0 4.3e-10 40.8 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Sacchrp_dh_NADP PF03435.18 CRK33465.1 - 0.04 14.2 0.0 0.072 13.3 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Yop-YscD_ppl PF16693.5 CRK33465.1 - 0.087 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Inner membrane component of T3SS, periplasmic domain CFEM PF05730.11 CRK33466.1 - 3e-10 40.0 9.8 5.3e-10 39.3 9.8 1.4 1 0 0 1 1 1 1 CFEM domain FmdE PF02663.14 CRK33466.1 - 0.047 13.7 0.0 0.064 13.3 0.0 1.3 1 0 0 1 1 1 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon BIR PF00653.21 CRK33467.1 - 6e-07 30.0 1.1 0.0003 21.4 0.7 2.7 2 1 0 2 2 2 1 Inhibitor of Apoptosis domain Glyco_hydro_72 PF03198.14 CRK33470.1 - 6.7e-122 406.7 2.1 9.7e-122 406.1 2.1 1.2 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 CRK33470.1 - 1.8e-23 83.0 7.3 5.9e-23 81.4 7.3 2.0 1 0 0 1 1 1 1 X8 domain MFS_1 PF07690.16 CRK33471.1 - 3e-25 88.9 14.7 3e-25 88.9 14.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Zn_clus PF00172.18 CRK33471.1 - 8.3e-06 25.8 7.7 1.5e-05 25.0 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.21 CRK33472.1 - 1.8e-58 198.1 0.0 2.6e-58 197.6 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Shal-type PF11601.8 CRK33472.1 - 0.13 11.8 0.6 0.28 10.8 0.6 1.5 1 0 0 1 1 1 0 Shal-type voltage-gated potassium channels, N-terminal Epimerase PF01370.21 CRK33473.1 - 1.4e-20 73.8 0.0 1.8e-20 73.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CRK33473.1 - 1.7e-12 46.9 0.0 2.2e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 CRK33473.1 - 4.3e-11 42.8 0.0 6.4e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 CRK33473.1 - 7.9e-07 28.5 0.0 0.014 14.6 0.0 2.6 2 1 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 CRK33473.1 - 3e-05 23.3 0.0 4.1e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 CRK33473.1 - 0.00055 19.9 0.0 0.00087 19.2 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Ldh_1_N PF00056.23 CRK33473.1 - 0.0021 18.2 0.0 0.003 17.7 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain adh_short PF00106.25 CRK33473.1 - 0.0028 17.1 0.0 0.033 13.7 0.0 2.5 2 1 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.13 CRK33473.1 - 0.015 14.8 0.0 0.29 10.7 0.0 2.1 2 0 0 2 2 2 0 NmrA-like family Polysacc_synt_2 PF02719.15 CRK33473.1 - 0.039 13.1 0.0 0.2 10.8 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Kelch_3 PF13415.6 CRK33473.1 - 0.13 12.6 0.0 7.3 7.0 0.0 2.5 2 0 0 2 2 2 0 Galactose oxidase, central domain KR PF08659.10 CRK33473.1 - 0.18 11.7 0.0 0.42 10.5 0.0 1.7 1 1 0 1 1 1 0 KR domain FMN_dh PF01070.18 CRK33474.1 - 6.1e-76 255.7 0.0 6.9e-76 255.5 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 CRK33474.1 - 2.3e-05 23.6 0.9 0.00048 19.2 0.4 2.6 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 CRK33474.1 - 3e-05 23.3 0.1 6.6e-05 22.2 0.0 1.4 1 1 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.14 CRK33474.1 - 4.7e-05 22.8 0.3 0.0063 15.9 0.0 2.3 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG NMO PF03060.15 CRK33474.1 - 0.0016 17.9 0.0 0.0025 17.3 0.0 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase Nup54_C PF18437.1 CRK33474.1 - 0.088 12.7 0.1 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 Nup54 C-terminal interacting domain Pet191_N PF10203.9 CRK33475.1 - 2.9e-28 97.9 4.6 4e-28 97.5 4.6 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 COBRA PF04833.15 CRK33475.1 - 0.016 15.1 0.4 0.023 14.6 0.4 1.2 1 0 0 1 1 1 0 COBRA-like protein PAN_3 PF08277.12 CRK33475.1 - 0.11 12.3 0.5 0.19 11.5 0.5 1.4 1 0 0 1 1 1 0 PAN-like domain Clusterin PF01093.17 CRK33475.1 - 0.11 11.5 1.8 0.13 11.2 1.8 1.2 1 0 0 1 1 1 0 Clusterin CX9C PF16860.5 CRK33475.1 - 0.29 11.2 8.7 0.45 10.6 1.1 2.8 1 1 2 3 3 3 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 CRK33475.1 - 0.29 11.2 5.1 1.9 8.6 0.7 2.5 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Med21 PF11221.8 CRK33476.1 - 0.0015 18.8 10.5 0.0045 17.3 1.2 4.6 5 0 0 5 5 3 2 Subunit 21 of Mediator complex zf-C3H1 PF10650.9 CRK33476.1 - 0.0045 16.7 2.1 0.0079 15.9 2.1 1.4 1 0 0 1 1 1 1 Putative zinc-finger domain PI3K_P85_iSH2 PF16454.5 CRK33476.1 - 0.017 14.7 10.6 0.89 9.1 1.8 2.9 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Golgin_A5 PF09787.9 CRK33476.1 - 0.019 14.5 7.0 1.3 8.4 1.6 2.6 2 0 0 2 2 2 0 Golgin subfamily A member 5 SF-assemblin PF06705.11 CRK33476.1 - 0.05 13.0 4.2 3.2 7.0 0.5 2.3 2 0 0 2 2 2 0 SF-assemblin/beta giardin zf-CCCH PF00642.24 CRK33476.1 - 0.089 12.7 0.2 0.15 12.0 0.2 1.3 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) tRNA_edit PF04073.15 CRK33476.1 - 0.15 12.1 0.0 17 5.5 0.0 2.5 2 0 0 2 2 2 0 Aminoacyl-tRNA editing domain Spc7 PF08317.11 CRK33476.1 - 0.52 9.1 13.3 2.4 6.9 2.5 2.8 2 0 0 2 2 2 0 Spc7 kinetochore protein SNase PF00565.17 CRK33476.1 - 1.1 9.8 5.0 44 4.6 0.0 3.8 4 0 0 4 4 4 0 Staphylococcal nuclease homologue DUF641 PF04859.12 CRK33476.1 - 1.4 9.2 17.1 1 9.7 1.3 3.3 3 0 0 3 3 2 0 Plant protein of unknown function (DUF641) DUF3160 PF11369.8 CRK33476.1 - 1.6 7.1 5.3 1.7 7.0 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3160) DUF4201 PF13870.6 CRK33476.1 - 2.7 7.7 16.0 1.5 8.5 1.5 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4201) DUF4404 PF14357.6 CRK33476.1 - 3.1 8.5 9.7 16 6.2 1.7 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Gp58 PF07902.11 CRK33476.1 - 4.6 5.4 5.3 15 3.7 0.3 2.4 2 0 0 2 2 2 0 gp58-like protein BRE1 PF08647.11 CRK33476.1 - 6.4 6.9 41.1 0.02 15.0 2.1 5.4 6 0 0 6 6 6 0 BRE1 E3 ubiquitin ligase Myosin_head PF00063.21 CRK33477.1 - 3.7e-269 894.6 0.0 8.1e-269 893.5 0.0 1.6 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 CRK33477.1 - 4.3e-17 61.3 389.2 5.3e-11 41.1 48.6 9.4 2 2 5 7 7 7 6 Myosin tail Myosin_N PF02736.19 CRK33477.1 - 5.5e-12 45.3 0.2 1.3e-11 44.2 0.2 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Filament PF00038.21 CRK33477.1 - 0.013 15.2 316.5 0.0045 16.6 11.6 16.9 2 2 11 15 15 15 0 Intermediate filament protein UDPG_MGDP_dh_N PF03721.14 CRK33477.1 - 0.028 14.0 13.3 0.35 10.4 4.8 2.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF150_C PF17384.2 CRK33477.1 - 0.036 14.2 4.7 9.2 6.5 0.0 4.2 4 0 0 4 4 4 0 RimP C-terminal SH3 domain AAA_22 PF13401.6 CRK33477.1 - 0.097 12.9 0.0 0.097 12.9 0.0 5.4 5 0 0 5 5 5 0 AAA domain Annexin PF00191.20 CRK33478.1 - 4e-18 65.2 1.7 0.00034 20.6 0.0 4.4 4 0 0 4 4 4 4 Annexin GPI2 PF06432.11 CRK33479.1 - 5.8e-128 426.2 1.4 6.9e-128 426.0 1.4 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Trypan_PARP PF05887.11 CRK33479.1 - 3.5 7.6 8.5 1.2 9.1 5.1 2.1 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) CFEM PF05730.11 CRK33481.1 - 2.3e-10 40.4 8.7 4.2e-10 39.6 8.7 1.5 1 0 0 1 1 1 1 CFEM domain DUF3246 PF11596.8 CRK33481.1 - 0.0004 19.9 7.4 0.00045 19.7 7.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3246) Sporozoite_P67 PF05642.11 CRK33481.1 - 0.056 11.5 5.4 0.062 11.4 5.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF3245 PF11595.8 CRK33481.1 - 0.075 13.5 1.7 0.1 13.1 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) Pinin_SDK_N PF04697.13 CRK33481.1 - 0.11 13.2 0.8 0.15 12.7 0.8 1.2 1 0 0 1 1 1 0 pinin/SDK conserved region MGC-24 PF05283.11 CRK33481.1 - 0.66 10.4 6.8 0.94 9.9 6.8 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Metallophos_2 PF12850.7 CRK33482.1 - 0.006 16.8 0.0 0.014 15.6 0.0 1.5 1 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Transp_inhibit PF18791.1 CRK33482.1 - 0.079 12.5 0.1 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 Transport inhibitor response 1 protein domain Aldolase_II PF00596.21 CRK33482.1 - 0.089 12.7 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Class II Aldolase and Adducin N-terminal domain GFO_IDH_MocA PF01408.22 CRK33483.1 - 7.9e-12 46.1 0.0 1.5e-11 45.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 CRK33483.1 - 0.00052 20.6 0.0 0.00091 19.9 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 CRK33483.1 - 0.079 13.4 0.0 0.54 10.7 0.0 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Sugar_tr PF00083.24 CRK33484.1 - 4.5e-51 174.1 7.3 6.2e-51 173.7 7.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Zn_clus PF00172.18 CRK33484.1 - 1.4e-08 34.7 9.0 2.5e-08 33.9 9.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 CRK33484.1 - 1.7e-05 24.0 10.5 1.7e-05 24.0 10.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ESSS PF10183.9 CRK33484.1 - 0.32 11.2 1.4 0.59 10.4 0.4 1.9 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Glycos_transf_1 PF00534.20 CRK33485.1 - 8.8e-30 103.5 0.0 1.3e-29 103.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CRK33485.1 - 3e-27 95.7 0.1 5.1e-27 94.9 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 CRK33485.1 - 3.1e-11 43.5 0.0 9e-11 42.0 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CRK33485.1 - 7.5e-07 29.3 0.1 0.00092 19.2 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 CRK33485.1 - 0.023 15.1 0.0 0.023 15.1 0.0 3.4 2 1 1 3 3 3 0 Glycosyl transferase 4-like domain GlgS PF08971.11 CRK33485.1 - 0.15 12.1 0.1 0.3 11.1 0.1 1.4 1 0 0 1 1 1 0 Glycogen synthesis protein p450 PF00067.22 CRK33487.1 - 2.8e-69 234.0 0.0 3.7e-69 233.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Acyl-CoA_dh_1 PF00441.24 CRK33488.1 - 1.1e-36 126.3 0.1 1.5e-36 125.9 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 CRK33488.1 - 9.9e-19 67.3 0.1 1.7e-18 66.6 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 CRK33488.1 - 1.4e-12 48.2 0.0 2.8e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 CRK33488.1 - 2.2e-09 37.7 0.0 3.6e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Fungal_trans PF04082.18 CRK33489.1 - 8e-16 57.9 0.2 1.6e-15 56.8 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK33489.1 - 8.1e-06 25.9 9.5 1.4e-05 25.2 9.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dabb PF07876.12 CRK33490.1 - 2e-12 47.6 0.0 2.2e-12 47.4 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Tudor_FRX1 PF18336.1 CRK33490.1 - 0.0019 18.1 0.0 0.0037 17.1 0.0 1.5 1 0 0 1 1 1 1 Fragile X mental retardation Tudor domain FAA_hydrolase PF01557.18 CRK33491.1 - 2.3e-54 184.4 0.0 3.2e-54 183.9 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 CRK33491.1 - 1e-31 109.3 0.0 1.8e-31 108.5 0.0 1.4 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal HgmA PF04209.13 CRK33492.1 - 8.6e-193 640.8 0.0 9.9e-193 640.6 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase AA_permease_2 PF13520.6 CRK33493.1 - 8.2e-56 189.6 47.8 1e-55 189.3 47.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CRK33493.1 - 4.2e-24 85.0 44.5 5e-24 84.7 44.5 1.1 1 0 0 1 1 1 1 Amino acid permease Fimbrial_K88 PF02432.15 CRK33493.1 - 0.18 11.7 2.2 0.34 10.9 0.1 2.2 2 0 0 2 2 2 0 Fimbrial, major and minor subunit Cu_amine_oxidN3 PF02728.16 CRK33494.1 - 8.1e-10 39.0 0.1 4.7e-09 36.6 0.0 2.0 2 0 0 2 2 2 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 CRK33494.1 - 9.4e-08 32.2 0.1 2e-07 31.2 0.1 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cyt-b5 PF00173.28 CRK33495.1 - 1e-18 67.2 0.0 1.7e-18 66.5 0.0 1.3 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DHDPS PF00701.22 CRK33496.1 - 1.1e-36 126.1 0.0 1.4e-36 125.8 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Sugar_tr PF00083.24 CRK33497.1 - 3.9e-62 210.6 9.0 7e-62 209.8 9.0 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK33497.1 - 9e-17 61.0 14.6 1.8e-16 60.0 14.1 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_5 PF05631.14 CRK33497.1 - 0.0092 14.9 0.5 0.0092 14.9 0.5 2.2 3 1 0 3 3 3 1 Sugar-tranasporters, 12 TM adh_short PF00106.25 CRK33498.1 - 2.2e-29 102.3 0.3 4.6e-29 101.3 0.1 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK33498.1 - 6.7e-21 74.9 0.9 2.1e-20 73.3 0.9 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK33498.1 - 2.3e-14 53.7 0.1 1.1e-13 51.5 0.1 2.0 2 1 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 CRK33498.1 - 0.0062 15.7 0.0 0.0075 15.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Ank_2 PF12796.7 CRK33499.1 - 3.9e-43 145.9 5.4 3.2e-12 46.9 0.2 6.2 3 2 4 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CRK33499.1 - 2.9e-36 123.4 9.1 3.1e-07 30.8 0.0 9.9 2 1 9 11 11 11 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 CRK33499.1 - 1.4e-31 105.0 6.5 0.0051 17.2 0.0 12.7 13 0 0 13 13 13 7 Ankyrin repeat Ank_5 PF13857.6 CRK33499.1 - 1.9e-24 85.4 11.4 0.00019 21.6 0.0 9.9 5 3 6 11 11 11 7 Ankyrin repeats (many copies) Ank PF00023.30 CRK33499.1 - 1.4e-16 60.1 31.4 0.13 12.7 0.1 11.8 12 0 0 12 12 12 9 Ankyrin repeat Peptidase_C25 PF01364.18 CRK33501.1 - 3.6e-113 378.6 0.0 4.3e-113 378.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C25 GMC_oxred_N PF00732.19 CRK33504.1 - 9.1e-55 186.1 0.2 1.2e-54 185.7 0.2 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CRK33504.1 - 5.1e-35 121.1 0.0 2.9e-34 118.6 0.0 2.1 2 0 0 2 2 2 1 GMC oxidoreductase Lycopene_cycl PF05834.12 CRK33504.1 - 0.00012 21.3 2.8 0.00013 21.2 0.4 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 CRK33504.1 - 0.00061 19.5 1.8 0.0094 15.6 0.6 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CRK33504.1 - 0.00069 18.9 0.3 0.0028 16.9 0.0 2.1 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CRK33504.1 - 0.001 19.2 0.1 0.0037 17.5 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CRK33504.1 - 0.032 13.5 2.1 0.04 13.2 0.3 2.0 3 0 0 3 3 3 0 Thi4 family Trp_halogenase PF04820.14 CRK33504.1 - 0.069 12.0 0.4 0.12 11.2 0.4 1.3 1 0 0 1 1 1 0 Tryptophan halogenase TrkA_N PF02254.18 CRK33504.1 - 0.097 12.9 0.2 0.84 9.9 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox_3 PF13738.6 CRK33504.1 - 0.42 9.8 1.7 4.5 6.4 0.9 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CRK33504.1 - 0.92 8.5 5.3 0.12 11.4 0.5 1.9 2 0 0 2 2 2 0 FAD binding domain Pectate_lyase PF03211.13 CRK33505.1 - 1.4e-85 286.0 10.9 1.6e-85 285.8 10.9 1.0 1 0 0 1 1 1 1 Pectate lyase RAI16-like PF10257.9 CRK33506.1 - 1e-71 241.7 1.1 1.5e-71 241.2 1.1 1.2 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein DNA_pol_phi PF04931.13 CRK33506.1 - 1.2 7.1 4.6 2.3 6.2 4.6 1.3 1 0 0 1 1 1 0 DNA polymerase phi KR PF08659.10 CRK33507.1 - 8e-50 169.2 0.0 2.2e-49 167.8 0.0 1.8 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 CRK33507.1 - 3.2e-44 151.4 0.0 6.4e-44 150.4 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 CRK33507.1 - 1.5e-42 146.2 0.1 2.6e-42 145.4 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.26 CRK33507.1 - 4.8e-22 78.8 0.9 2.2e-15 56.9 0.3 2.4 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain PP-binding PF00550.25 CRK33507.1 - 3.4e-05 24.1 0.0 8.4e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site SAT PF16073.5 CRK33507.1 - 0.00016 21.5 0.1 0.022 14.5 0.1 2.7 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis KAsynt_C_assoc PF16197.5 CRK33507.1 - 0.00098 19.6 0.0 0.0028 18.1 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension DUF4171 PF13775.6 CRK33507.1 - 0.16 12.4 0.0 0.32 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4171) TTL PF03133.15 CRK33508.1 - 1.6e-31 109.5 0.0 5.7e-31 107.7 0.0 1.7 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 CRK33508.1 - 0.00025 20.4 0.0 0.00043 19.6 0.0 1.3 1 0 0 1 1 1 1 YheC/D like ATP-grasp Dala_Dala_lig_C PF07478.13 CRK33508.1 - 0.0021 17.6 0.0 0.012 15.1 0.0 2.0 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus adh_short PF00106.25 CRK33509.1 - 7.5e-18 64.7 0.0 1e-17 64.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK33509.1 - 1.3e-09 38.0 0.0 2e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK33509.1 - 0.00077 19.4 0.0 0.0013 18.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CRK33509.1 - 0.0048 16.4 0.0 0.0097 15.4 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TIR-like PF10137.9 CRK33509.1 - 0.083 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain Shikimate_DH PF01488.20 CRK33509.1 - 0.099 12.7 0.0 0.21 11.7 0.0 1.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 CRK33509.1 - 0.14 12.0 0.1 1.8 8.4 0.0 2.1 2 0 0 2 2 2 0 NAD(P)H-binding Pkinase PF00069.25 CRK33511.1 - 0.017 14.5 0.0 0.029 13.7 0.0 1.5 1 1 0 1 1 1 0 Protein kinase domain Peptidase_M20 PF01546.28 CRK33513.1 - 2.1e-26 92.9 0.0 1.9e-25 89.8 0.0 2.4 2 1 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CRK33513.1 - 6.5e-21 74.3 0.2 1.3e-20 73.3 0.2 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain F-box-like PF12937.7 CRK33513.1 - 0.024 14.5 0.1 0.07 13.0 0.1 1.7 1 0 0 1 1 1 0 F-box-like Myb_Cef PF11831.8 CRK33513.1 - 0.061 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 pre-mRNA splicing factor component DUF5129 PF17173.4 CRK33513.1 - 0.069 12.3 0.1 0.18 10.9 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5129) DUF218 PF02698.17 CRK33514.1 - 1e-08 35.2 0.0 1.9e-08 34.4 0.0 1.5 1 1 0 1 1 1 1 DUF218 domain MFS_1 PF07690.16 CRK33515.1 - 9.6e-27 93.8 23.2 9.6e-27 93.8 23.2 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Corona_M PF01635.18 CRK33515.1 - 0.13 11.6 7.3 1.2 8.4 0.1 2.7 3 0 0 3 3 3 0 Coronavirus M matrix/glycoprotein Glyco_trans_1_4 PF13692.6 CRK33531.1 - 0.00019 21.9 0.0 0.001 19.5 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 CRK33531.1 - 0.067 12.7 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 Cation_efflux PF01545.21 CRK33532.1 - 9.8e-46 156.0 2.7 1.3e-45 155.6 2.7 1.2 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.22 CRK33532.1 - 0.001 18.4 7.1 0.001 18.4 7.1 3.7 1 1 1 2 2 2 1 ZIP Zinc transporter Mito_carr PF00153.27 CRK33533.1 - 2.5e-56 187.6 3.0 3.7e-18 65.2 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein BKACE PF05853.12 CRK33533.1 - 0.09 12.1 0.4 0.17 11.2 0.4 1.4 1 0 0 1 1 1 0 beta-keto acid cleavage enzyme His_Phos_1 PF00300.22 CRK33534.1 - 9.3e-06 25.5 2.6 0.0049 16.6 0.1 4.0 3 1 0 3 3 3 2 Histidine phosphatase superfamily (branch 1) Peptidase_C13 PF01650.18 CRK33535.1 - 2.1e-39 135.6 0.2 3.4e-39 134.9 0.2 1.3 1 0 0 1 1 1 1 Peptidase C13 family TFIIIC_delta PF12657.7 CRK33535.1 - 4.8e-15 56.0 0.0 1.3e-14 54.5 0.0 1.8 1 0 0 1 1 1 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.7 CRK33535.1 - 4.5e-11 42.6 1.3 9.7e-11 41.5 1.3 1.6 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex DNA_topoisoIV PF00521.20 CRK33536.1 - 8.5e-118 393.9 0.1 2.8e-117 392.2 0.0 2.0 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 CRK33536.1 - 9.5e-49 164.9 4.5 9.5e-49 164.9 4.5 2.4 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 CRK33536.1 - 2e-27 95.8 0.5 4.2e-27 94.7 0.5 1.5 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 CRK33536.1 - 9.3e-15 55.1 0.1 2.5e-14 53.7 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 CRK33536.1 - 1.9e-06 28.0 0.0 7.4e-06 26.1 0.0 2.1 1 0 0 1 1 1 1 Toprim domain APAF1_C PF17908.1 CRK33536.1 - 0.017 15.1 0.4 0.053 13.5 0.4 1.8 1 0 0 1 1 1 0 APAF-1 helical domain Reticulon PF02453.17 CRK33537.1 - 2.6e-35 121.7 3.0 3.6e-35 121.3 3.0 1.2 1 0 0 1 1 1 1 Reticulon DUF4107 PF13389.6 CRK33537.1 - 0.014 15.6 0.0 0.023 14.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4107) FUSC_2 PF13515.6 CRK33537.1 - 0.16 12.1 4.1 3.6 7.7 0.5 2.2 2 0 0 2 2 2 0 Fusaric acid resistance protein-like RabGAP-TBC PF00566.18 CRK33538.1 - 2e-43 148.6 0.0 5.1e-43 147.2 0.0 1.7 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ZapB PF06005.12 CRK33538.1 - 0.019 15.4 17.5 0.36 11.3 1.8 3.6 2 0 0 2 2 2 0 Cell division protein ZapB zf-C4H2 PF10146.9 CRK33538.1 - 0.025 14.9 0.0 0.025 14.9 0.0 3.6 3 1 0 3 3 3 0 Zinc finger-containing protein DUF1687 PF07955.11 CRK33538.1 - 0.043 14.3 2.2 0.2 12.2 2.2 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1687) YabA PF06156.13 CRK33538.1 - 3 8.5 10.3 7.9 7.2 0.4 3.6 3 0 0 3 3 3 0 Initiation control protein YabA TSC22 PF01166.18 CRK33538.1 - 6.3 7.2 11.8 3.7 7.9 2.4 3.5 3 0 0 3 3 3 0 TSC-22/dip/bun family Macoilin PF09726.9 CRK33539.1 - 0.11 11.1 17.6 0.13 10.7 17.6 1.1 1 0 0 1 1 1 0 Macoilin family Otopetrin PF03189.13 CRK33539.1 - 0.77 8.5 8.7 0.95 8.2 8.7 1.3 1 0 0 1 1 1 0 Otopetrin MAP65_ASE1 PF03999.12 CRK33539.1 - 3.5 6.2 29.2 5.2 5.7 29.2 1.4 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) FliP PF00813.20 CRK33539.1 - 3.8 7.3 12.4 7.7 6.4 12.4 1.5 1 0 0 1 1 1 0 FliP family GREB1 PF15782.5 CRK33539.1 - 6.7 3.7 27.9 8.2 3.4 27.9 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Lipase_GDSL_2 PF13472.6 CRK33540.1 - 1.1e-06 29.2 0.2 1.5e-06 28.8 0.2 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 CRK33540.1 - 0.0052 16.8 0.4 0.0096 15.9 0.4 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Aminotran_1_2 PF00155.21 CRK33541.1 - 1.1e-63 215.6 0.0 1.4e-63 215.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II MscL PF01741.18 CRK33544.1 - 3.8e-19 69.2 0.0 4.6e-19 68.9 0.0 1.1 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL C1_1 PF00130.22 CRK33544.1 - 0.038 13.9 1.0 0.062 13.2 1.0 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DZR PF12773.7 CRK33544.1 - 0.04 13.9 0.5 0.063 13.3 0.5 1.3 1 0 0 1 1 1 0 Double zinc ribbon Zn_ribbon_17 PF17120.5 CRK33544.1 - 0.32 10.7 3.0 0.48 10.1 3.0 1.2 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type SUR7 PF06687.12 CRK33545.1 - 5.8e-25 88.2 0.1 6.9e-25 87.9 0.1 1.0 1 0 0 1 1 1 1 SUR7/PalI family Trp_oprn_chp PF09534.10 CRK33545.1 - 0.21 11.4 7.3 0.33 10.7 7.3 1.3 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Fig1 PF12351.8 CRK33545.1 - 1.8 8.5 12.9 0.064 13.2 6.4 2.0 2 1 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 NDT80_PhoG PF05224.12 CRK33547.1 - 1.4e-46 159.0 0.0 2e-46 158.6 0.0 1.2 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Pterin_bind PF00809.22 CRK33548.1 - 1.8e-76 257.1 0.0 2.3e-76 256.7 0.0 1.2 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 CRK33548.1 - 1.8e-73 244.2 0.0 6e-35 120.1 0.0 3.1 3 0 0 3 3 3 2 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) DUF3939 PF13075.6 CRK33548.1 - 0.00035 20.6 0.0 0.55 10.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3939) NMO PF03060.15 CRK33549.1 - 7.9e-58 196.4 2.9 1.1e-57 195.9 2.9 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 CRK33549.1 - 1.2e-10 41.0 3.4 2.3e-10 40.0 3.4 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 CRK33549.1 - 1.1e-06 27.9 4.4 1.7e-06 27.3 4.4 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 CRK33549.1 - 0.006 15.8 0.5 0.011 14.9 0.5 1.5 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.21 CRK33549.1 - 0.086 12.0 0.4 0.12 11.5 0.4 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase ArfGap PF01412.18 CRK33550.1 - 2.2e-35 121.3 1.0 3.8e-35 120.5 1.0 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf TIM21 PF08294.11 CRK33551.1 - 6.9e-43 146.0 0.0 8.5e-43 145.7 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.10 CRK33551.1 - 1.9e-07 30.9 0.0 3.3e-07 30.1 0.0 1.4 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 zf-H2C2_2 PF13465.6 CRK33555.1 - 5.4e-09 36.1 21.3 1.9e-05 24.9 3.5 4.5 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 CRK33555.1 - 1.2e-06 28.6 20.0 0.00043 20.6 4.5 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 CRK33555.1 - 0.02 15.2 3.0 0.05 13.9 0.4 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CRK33555.1 - 0.029 14.4 2.3 2.2 8.3 0.3 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_4 PF13894.6 CRK33555.1 - 0.049 14.5 3.1 0.049 14.5 3.1 3.6 4 0 0 4 4 4 0 C2H2-type zinc finger FOXP-CC PF16159.5 CRK33555.1 - 0.12 13.0 0.2 0.12 13.0 0.2 3.0 3 1 1 4 4 4 0 FOXP coiled-coil domain DUF2225 PF09986.9 CRK33555.1 - 0.35 10.6 0.8 0.93 9.2 0.8 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-H2C2_5 PF13909.6 CRK33555.1 - 0.97 9.2 11.9 2.9 7.7 0.1 3.9 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Rad51 PF08423.11 CRK33557.1 - 8.9e-10 38.3 0.2 0.0083 15.4 0.0 3.2 3 0 0 3 3 3 3 Rad51 ATPase PF06745.13 CRK33557.1 - 0.00029 20.2 0.0 0.00048 19.6 0.0 1.3 1 0 0 1 1 1 1 KaiC Peptidase_M18 PF02127.15 CRK33557.1 - 0.00099 18.0 2.0 0.58 8.9 0.2 2.1 2 0 0 2 2 2 2 Aminopeptidase I zinc metalloprotease (M18) FAD_SOX PF18371.1 CRK33557.1 - 0.0042 17.4 0.0 4.5 7.7 0.0 2.3 2 0 0 2 2 2 2 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase DUF4960 PF16324.5 CRK33557.1 - 0.016 14.8 0.2 4 6.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4960) RecA PF00154.21 CRK33557.1 - 0.02 14.4 0.0 0.045 13.2 0.0 1.6 1 0 0 1 1 1 0 recA bacterial DNA recombination protein CBM64 PF18666.1 CRK33557.1 - 0.12 12.5 0.2 26 5.0 0.0 2.4 2 0 0 2 2 2 0 Carbohydrate-binding module 64 nsp7 PF08716.10 CRK33557.1 - 0.13 12.9 0.7 22 5.8 0.1 2.6 2 0 0 2 2 2 0 nsp7 replicase DUF2793 PF10983.8 CRK33557.1 - 0.17 11.8 4.0 1.8 8.5 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2793) Defensin_3 PF08131.11 CRK33557.1 - 0.36 11.0 0.9 26 5.1 0.1 2.3 2 0 0 2 2 2 0 Defensin-like peptide family DnaB_C PF03796.15 CRK33557.1 - 0.56 9.5 1.5 13 5.0 0.1 2.8 3 0 0 3 3 3 0 DnaB-like helicase C terminal domain AAA_25 PF13481.6 CRK33557.1 - 6.1 6.4 7.4 0.99 8.9 0.1 2.8 3 0 0 3 3 3 0 AAA domain SDA1 PF05285.12 CRK33557.1 - 7.3 5.9 9.0 27 4.1 4.5 2.2 2 0 0 2 2 2 0 SDA1 SLATT_fungal PF18142.1 CRK33558.1 - 6.3e-26 90.7 0.2 8e-26 90.4 0.2 1.1 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain Helo_like_N PF17111.5 CRK33559.1 - 1.7e-13 50.4 0.7 3.3e-13 49.5 0.7 1.4 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins SesA PF17107.5 CRK33559.1 - 0.051 13.8 0.0 0.094 12.9 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases TRM PF02005.16 CRK33560.1 - 9.7e-103 344.2 0.0 1.2e-89 301.1 0.0 2.0 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Methyltr_RsmB-F PF01189.17 CRK33560.1 - 0.089 12.4 0.0 1.4 8.5 0.0 2.2 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F zf-CCHC_5 PF14787.6 CRK33560.1 - 1.3 8.8 5.0 1.1 9.1 0.9 2.4 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger Ycf66_N PF07444.11 CRK33561.1 - 0.16 12.1 0.0 0.32 11.2 0.0 1.4 1 0 0 1 1 1 0 Ycf66 protein N-terminus Sugar_tr PF00083.24 CRK33563.1 - 6.3e-101 338.5 19.8 8.8e-101 338.0 19.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter ABC_tran PF00005.27 CRK33563.1 - 4.9e-45 153.4 4.1 7.3e-22 78.4 0.0 3.6 3 1 0 3 3 2 2 ABC transporter MFS_1 PF07690.16 CRK33563.1 - 2.1e-25 89.4 21.5 3.6e-25 88.6 21.5 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily AAA_21 PF13304.6 CRK33563.1 - 1.2e-10 41.7 2.5 0.00052 19.9 0.0 4.2 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system MFS_4 PF06779.14 CRK33563.1 - 2e-09 37.2 3.2 3.5e-09 36.4 3.2 1.3 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB AAA_29 PF13555.6 CRK33563.1 - 1.2e-07 31.4 0.1 0.00036 20.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 CRK33563.1 - 1.4e-07 31.2 2.1 0.055 12.9 0.0 4.5 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 CRK33563.1 - 3e-06 27.3 0.2 0.16 12.1 0.0 3.1 3 0 0 3 3 2 2 50S ribosome-binding GTPase ABC_tran_Xtn PF12848.7 CRK33563.1 - 3e-06 27.2 3.8 1.2e-05 25.2 3.8 2.0 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 CRK33563.1 - 1.8e-05 24.7 1.0 0.036 14.0 0.0 3.0 3 0 0 3 3 3 2 RsgA GTPase AAA_28 PF13521.6 CRK33563.1 - 2.7e-05 24.5 0.9 0.0058 16.9 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.6 CRK33563.1 - 0.00027 21.5 0.1 1.2 9.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 CRK33563.1 - 0.00035 21.1 10.0 0.025 15.1 0.0 3.6 4 0 0 4 4 4 1 AAA domain DUF87 PF01935.17 CRK33563.1 - 0.00038 20.6 4.4 0.48 10.5 0.0 3.1 3 0 0 3 3 3 2 Helicase HerA, central domain AAA_22 PF13401.6 CRK33563.1 - 0.00053 20.3 0.1 0.72 10.1 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CRK33563.1 - 0.0007 19.8 0.1 2.2 8.4 0.0 3.0 2 0 0 2 2 2 2 AAA domain TRI12 PF06609.13 CRK33563.1 - 0.00079 18.0 5.5 0.079 11.4 0.6 2.2 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) NACHT PF05729.12 CRK33563.1 - 0.00094 19.1 0.1 0.073 13.0 0.0 2.7 2 0 0 2 2 2 1 NACHT domain MeaB PF03308.16 CRK33563.1 - 0.0014 17.6 0.6 0.98 8.3 0.1 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 CRK33563.1 - 0.002 17.9 0.8 1.3 8.7 0.1 3.0 3 0 0 3 3 3 1 AAA domain AAA_27 PF13514.6 CRK33563.1 - 0.0025 17.4 0.5 0.15 11.6 0.0 3.0 3 0 0 3 3 3 1 AAA domain MFS_1_like PF12832.7 CRK33563.1 - 0.003 16.5 6.4 1.3 7.8 0.1 3.2 2 1 1 3 3 3 2 MFS_1 like family AAA_15 PF13175.6 CRK33563.1 - 0.0091 15.7 3.1 0.031 14.0 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain AAA_16 PF13191.6 CRK33563.1 - 0.013 15.9 6.2 0.37 11.2 0.4 2.9 2 2 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.12 CRK33563.1 - 0.018 14.3 0.1 2.7 7.2 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.22 CRK33563.1 - 0.024 15.0 0.0 2.3 8.7 0.0 2.5 2 0 0 2 2 2 0 RNA helicase PUCC PF03209.15 CRK33563.1 - 0.024 13.7 7.3 0.043 12.8 7.3 1.3 1 0 0 1 1 1 0 PUCC protein KapB PF08810.10 CRK33563.1 - 0.026 14.7 0.8 0.41 10.8 0.1 2.3 2 0 0 2 2 2 0 Kinase associated protein B TsaE PF02367.17 CRK33563.1 - 0.066 13.2 0.4 3.9 7.5 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 CRK33563.1 - 0.07 13.6 0.1 1.8 9.0 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_13 PF13166.6 CRK33563.1 - 0.093 11.4 5.5 2.1 6.9 0.0 3.2 3 0 0 3 3 3 0 AAA domain Thymidylate_kin PF02223.17 CRK33563.1 - 0.095 12.4 3.3 2 8.1 0.0 2.9 3 0 0 3 3 2 0 Thymidylate kinase NTPase_1 PF03266.15 CRK33563.1 - 0.12 12.3 0.1 3.5 7.5 0.0 2.8 3 0 0 3 3 3 0 NTPase ATP-synt_ab PF00006.25 CRK33563.1 - 0.14 11.8 0.1 15 5.2 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Arf PF00025.21 CRK33563.1 - 0.2 11.1 0.7 2.4 7.6 0.1 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family PDR_assoc PF08370.11 CRK33563.1 - 0.24 11.2 2.2 9.2 6.1 0.1 3.1 3 0 0 3 3 3 0 Plant PDR ABC transporter associated Dynamin_N PF00350.23 CRK33563.1 - 0.28 11.2 1.5 3.1 7.8 0.0 2.7 3 0 0 3 3 2 0 Dynamin family NB-ARC PF00931.22 CRK33563.1 - 0.81 8.8 6.8 1.4 8.0 0.0 3.2 3 0 0 3 3 3 0 NB-ARC domain AAA_14 PF13173.6 CRK33563.1 - 0.81 9.7 3.7 5.7 7.0 0.0 3.2 5 0 0 5 5 2 0 AAA domain AAA_17 PF13207.6 CRK33563.1 - 8.2 6.9 8.4 6.5 7.2 0.0 3.4 4 0 0 4 4 2 0 AAA domain Bromodomain PF00439.25 CRK33566.1 - 5.9e-16 58.3 0.6 1.2e-15 57.3 0.1 1.7 2 0 0 2 2 2 1 Bromodomain BTB PF00651.31 CRK33566.1 - 5.6e-06 26.6 0.0 1.9e-05 24.8 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain CHCH PF06747.13 CRK33566.1 - 1.7 8.9 3.5 26 5.1 0.1 2.4 2 0 0 2 2 2 0 CHCH domain APH PF01636.23 CRK33567.1 - 0.019 14.9 0.0 0.052 13.5 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family E1-E2_ATPase PF00122.20 CRK33568.1 - 5.4e-49 166.2 2.7 5.4e-49 166.2 2.7 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 CRK33568.1 - 2e-23 83.8 4.4 3.5e-23 83.0 4.4 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 CRK33568.1 - 4.9e-09 36.5 0.1 2e-08 34.5 0.2 2.1 2 0 0 2 2 2 1 Heavy-metal-associated domain HAD PF12710.7 CRK33568.1 - 0.0099 16.3 0.2 0.46 10.9 0.1 2.5 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase His_Phos_2 PF00328.22 CRK33570.1 - 2.8e-60 204.7 0.0 3.3e-60 204.5 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Molybdopterin_N PF18364.1 CRK33571.1 - 0.029 14.4 0.0 15 5.7 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin oxidoreductase N-terminal domain Phage_holin_3_6 PF07332.11 CRK33571.1 - 0.27 11.3 1.3 0.51 10.4 1.3 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Cas1_AcylT PF07779.12 CRK33572.1 - 8.4e-116 387.7 16.3 1.2e-115 387.2 16.3 1.1 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p PC-Esterase PF13839.6 CRK33572.1 - 0.0083 15.9 0.0 0.019 14.7 0.0 1.6 2 0 0 2 2 2 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Inositol_P PF00459.25 CRK33573.1 - 1.9e-64 217.8 0.0 2.7e-64 217.3 0.0 1.2 1 0 0 1 1 1 1 Inositol monophosphatase family MFS_1 PF07690.16 CRK33573.1 - 5.2e-32 111.1 30.4 6.1e-28 97.8 9.4 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK33573.1 - 2.6e-08 33.2 3.1 2.6e-08 33.2 3.1 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 CRK33573.1 - 0.0015 17.4 1.9 0.0015 17.4 1.9 2.6 3 0 0 3 3 3 1 MFS_1 like family Aconitase PF00330.20 CRK33574.1 - 3.5e-143 477.9 0.5 7.2e-136 453.8 0.0 2.2 2 0 0 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 CRK33574.1 - 2e-40 138.1 0.0 3.4e-40 137.4 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF2418 PF10332.9 CRK33576.1 - 5.6e-57 190.3 5.7 3.8e-38 129.9 0.4 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF2418) PRE_C2HC PF07530.11 CRK33576.1 - 0.098 12.8 0.0 18 5.5 0.0 2.5 2 0 0 2 2 2 0 Associated with zinc fingers DUF2909 PF11137.8 CRK33576.1 - 1.6 8.7 4.2 27 4.8 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2909) DUF3339 PF11820.8 CRK33576.1 - 2 8.7 5.9 20 5.4 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3339) ATP-synt_F PF01990.17 CRK33577.1 - 4.3e-34 116.7 0.1 5e-34 116.5 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit E1_DerP2_DerF2 PF02221.15 CRK33578.1 - 1.8e-28 99.6 0.1 2.1e-28 99.4 0.1 1.1 1 0 0 1 1 1 1 ML domain Alph_Pro_TM PF09608.10 CRK33578.1 - 0.011 15.5 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) DUF4832 PF16116.5 CRK33578.1 - 0.2 11.5 0.0 4.2 7.1 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4832) PHD PF00628.29 CRK33579.1 - 2e-08 34.0 10.0 3.3e-08 33.3 10.0 1.4 1 0 0 1 1 1 1 PHD-finger Glycos_transf_4 PF00953.21 CRK33580.1 - 2.3e-29 102.5 6.9 2.3e-29 102.5 6.9 1.9 3 0 0 3 3 3 1 Glycosyl transferase family 4 MFS_1 PF07690.16 CRK33581.1 - 5e-47 160.5 57.2 4e-46 157.6 37.1 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK33581.1 - 1.4e-08 34.1 18.5 2.8e-08 33.1 18.5 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 CRK33581.1 - 9.4e-07 28.4 6.8 9.4e-07 28.4 6.8 1.8 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB CPP1-like PF11833.8 CRK33581.1 - 0.2 11.3 2.0 0.28 10.8 0.0 2.2 3 0 0 3 3 3 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Spem1 PF15670.5 CRK33581.1 - 0.22 11.1 0.4 0.35 10.4 0.4 1.2 1 0 0 1 1 1 0 Spermatid maturation protein 1 TPPK_C PF12555.8 CRK33581.1 - 1.8 8.7 6.4 0.16 12.0 0.5 2.3 2 1 0 2 2 2 0 Thiamine pyrophosphokinase C terminal Transglut_core PF01841.19 CRK33582.1 - 4.5e-11 43.2 0.1 8.1e-11 42.4 0.1 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily Gln_amidase PF15644.6 CRK33582.1 - 0.11 13.6 0.1 0.32 12.0 0.1 1.9 1 0 0 1 1 1 0 Papain fold toxin 1, glutamine deamidase WD40 PF00400.32 CRK33583.1 - 2.8e-18 65.9 1.2 7.2e-05 23.5 0.0 3.8 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.8 CRK33583.1 - 0.00052 18.8 2.5 0.064 11.9 0.1 3.2 2 1 1 3 3 3 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 CRK33583.1 - 0.02 15.2 0.1 5.3 7.4 0.0 2.9 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Suppressor_APC PF11414.8 CRK33583.1 - 0.056 13.5 1.8 0.16 12.1 1.3 2.1 1 1 1 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein Seryl_tRNA_N PF02403.22 CRK33583.1 - 0.089 13.0 0.4 0.31 11.3 0.4 2.0 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain JAB PF01398.21 CRK33584.1 - 3.2e-06 27.1 0.0 6.2e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 CRK33584.1 - 0.00037 20.9 0.1 0.00091 19.6 0.1 1.7 1 1 0 1 1 1 1 Maintenance of mitochondrial structure and function Vps5 PF09325.10 CRK33586.1 - 7.9e-11 42.0 0.2 1.3e-10 41.3 0.2 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 CRK33586.1 - 1e-07 32.0 0.0 1.9e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 PX domain Cupin_8 PF13621.6 CRK33587.1 - 2.5e-31 109.3 0.0 6.7e-31 107.9 0.0 1.6 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 CRK33587.1 - 1.2e-08 34.8 0.0 1.3e-06 28.1 0.0 2.3 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.22 CRK33587.1 - 0.0047 17.3 0.0 0.025 15.0 0.0 2.0 2 0 0 2 2 2 1 JmjC domain, hydroxylase DUF812 PF05667.11 CRK33588.1 - 0.0032 16.4 3.7 0.0032 16.4 3.7 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF812) Herpes_UL6 PF01763.16 CRK33588.1 - 0.015 13.8 0.3 0.025 13.1 0.3 1.4 1 0 0 1 1 1 0 Herpesvirus UL6 like IFT57 PF10498.9 CRK33588.1 - 0.064 12.2 4.0 0.13 11.2 4.0 1.5 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 GAS PF13851.6 CRK33588.1 - 0.13 11.6 13.5 0.12 11.7 8.3 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding BLOC1_2 PF10046.9 CRK33588.1 - 0.13 12.5 7.9 0.86 9.9 3.5 3.0 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SWIRM-assoc_2 PF16496.5 CRK33588.1 - 0.29 10.0 6.8 3.4 6.4 0.3 2.4 2 0 0 2 2 2 0 SWIRM-associated domain at the N-terminal bZIP_1 PF00170.21 CRK33588.1 - 0.49 10.5 13.9 1.5 9.0 8.7 2.8 2 1 0 2 2 2 0 bZIP transcription factor Cep57_CLD_2 PF14197.6 CRK33588.1 - 0.59 10.3 10.2 6.9 6.8 4.8 2.7 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 DUF2205 PF10224.9 CRK33588.1 - 0.61 10.1 4.4 0.69 9.9 1.7 2.2 2 0 0 2 2 2 0 Short coiled-coil protein DHR10 PF18595.1 CRK33588.1 - 2 8.5 24.4 0.16 12.0 10.2 3.3 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain KxDL PF10241.9 CRK33588.1 - 2.5 8.5 14.8 1.8 8.9 2.5 3.4 3 0 0 3 3 3 0 Uncharacterized conserved protein Prefoldin_2 PF01920.20 CRK33588.1 - 2.6 8.1 11.1 2.1 8.4 6.2 2.5 2 0 0 2 2 2 0 Prefoldin subunit SOGA PF11365.8 CRK33588.1 - 3.4 8.8 13.7 0.46 11.6 4.5 3.1 3 0 0 3 3 3 0 Protein SOGA Nebulin PF00880.18 CRK33588.1 - 3.7 7.6 6.3 2.2 8.3 1.6 2.8 2 0 0 2 2 2 0 Nebulin repeat ADIP PF11559.8 CRK33588.1 - 7.7 6.6 18.2 0.17 11.9 6.6 2.8 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding SlyX PF04102.12 CRK33588.1 - 8.2 7.1 12.2 0.41 11.3 3.6 2.9 3 0 0 3 3 3 0 SlyX KASH_CCD PF14662.6 CRK33588.1 - 8.5 6.1 16.7 18 5.1 12.2 2.8 2 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH NYD-SP28_assoc PF14775.6 CRK33588.1 - 9.8 6.4 9.4 22 5.2 1.5 3.3 2 1 1 3 3 3 0 Sperm tail C-terminal domain EamA PF00892.20 CRK33589.1 - 0.00016 21.9 14.6 0.0014 18.8 14.6 2.0 1 1 0 1 1 1 1 EamA-like transporter family Oxidored_q6 PF01058.22 CRK33589.1 - 0.2 11.5 0.0 0.26 11.1 0.0 1.2 1 0 0 1 1 1 0 NADH ubiquinone oxidoreductase, 20 Kd subunit Voltage_CLC PF00654.20 CRK33590.1 - 2.8e-88 296.5 24.4 2.8e-88 296.5 24.4 1.8 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 CRK33590.1 - 1.8e-10 41.1 0.0 0.00018 21.9 0.0 2.5 2 0 0 2 2 2 2 CBS domain DEAD_assoc PF08494.11 CRK33590.1 - 0.12 12.1 0.5 0.49 10.2 0.0 2.2 3 0 0 3 3 3 0 DEAD/H associated Metallophos PF00149.28 CRK33591.1 - 1.2e-37 130.4 0.5 2e-37 129.7 0.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CRK33591.1 - 0.025 15.0 0.1 0.051 14.0 0.1 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 CRK33591.1 - 0.1 12.2 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain DUF3112 PF11309.8 CRK33592.1 - 1.3e-25 90.1 0.3 3.3e-17 62.7 0.0 2.9 3 1 1 4 4 4 2 Protein of unknown function (DUF3112) YvrJ PF12841.7 CRK33592.1 - 0.0072 15.8 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 YvrJ protein family DUF2207 PF09972.9 CRK33592.1 - 0.14 10.9 0.3 1 8.0 0.3 2.1 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) SH3_9 PF14604.6 CRK33593.1 - 2e-05 24.4 0.1 4e-05 23.4 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CRK33593.1 - 8.5e-05 22.1 0.1 0.00016 21.2 0.1 1.4 1 0 0 1 1 1 1 SH3 domain Podoplanin PF05808.11 CRK33593.1 - 0.0056 16.8 0.2 0.012 15.8 0.2 1.4 1 0 0 1 1 1 1 Podoplanin EphA2_TM PF14575.6 CRK33593.1 - 0.0082 17.0 0.0 0.017 15.9 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.15 CRK33593.1 - 0.029 14.1 2.6 0.073 12.8 2.6 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 CYYR1 PF10873.8 CRK33593.1 - 0.046 14.2 1.2 0.046 14.2 1.2 2.5 3 1 1 4 4 2 0 Cysteine and tyrosine-rich protein 1 DUF4690 PF15756.5 CRK33593.1 - 0.049 14.2 0.1 0.15 12.6 0.1 1.8 1 0 0 1 1 1 0 Small Novel Rich in Cartilage DAP10 PF07213.11 CRK33593.1 - 0.054 13.5 1.9 0.076 13.0 0.1 2.2 2 0 0 2 2 2 0 DAP10 membrane protein TMEM154 PF15102.6 CRK33593.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family SARAF PF06682.12 CRK33593.1 - 0.14 11.7 2.7 0.73 9.4 0.1 2.0 1 1 1 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Insulin_TMD PF17870.1 CRK33593.1 - 0.29 11.2 1.2 0.62 10.2 1.2 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Syndecan PF01034.20 CRK33593.1 - 0.49 10.4 2.8 1 9.3 2.8 1.4 1 0 0 1 1 1 0 Syndecan domain Pkinase PF00069.25 CRK33594.1 - 4.6e-42 144.2 0.0 8.2e-20 71.3 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain WD40 PF00400.32 CRK33594.1 - 1.8e-17 63.3 26.9 1.3e-06 29.0 0.1 8.5 8 0 0 8 8 8 3 WD domain, G-beta repeat HEAT PF02985.22 CRK33594.1 - 1.9e-15 55.6 18.0 0.12 12.6 0.1 12.5 14 0 0 14 14 13 4 HEAT repeat Pkinase_Tyr PF07714.17 CRK33594.1 - 3.2e-11 43.0 0.0 0.00024 20.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Cnd1 PF12717.7 CRK33594.1 - 6.1e-07 29.6 0.0 2.3 8.3 0.0 5.0 5 0 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Kinase-like PF14531.6 CRK33594.1 - 1.4e-05 24.6 0.0 0.18 11.1 0.0 2.6 2 0 0 2 2 2 2 Kinase-like HEAT_2 PF13646.6 CRK33594.1 - 3e-05 24.3 13.4 5.1 7.5 0.0 7.2 7 1 0 8 8 8 1 HEAT repeats SH3_9 PF14604.6 CRK33594.1 - 0.00012 21.9 0.1 0.00024 20.9 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CRK33594.1 - 0.00047 19.7 0.1 0.00097 18.7 0.1 1.5 1 0 0 1 1 1 1 SH3 domain HEAT_EZ PF13513.6 CRK33594.1 - 0.0014 19.1 8.6 4.1 8.0 0.3 5.1 4 0 0 4 4 4 2 HEAT-like repeat ANAPC4_WD40 PF12894.7 CRK33594.1 - 0.0048 17.2 0.1 14 6.0 0.0 3.9 3 2 2 5 5 4 0 Anaphase-promoting complex subunit 4 WD40 domain RTP1_C1 PF10363.9 CRK33594.1 - 0.0064 16.7 0.3 9 6.5 0.0 3.1 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 HTH_Tnp_ISL3 PF13542.6 CRK33594.1 - 0.015 14.7 0.0 8.8 5.8 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 Podoplanin PF05808.11 CRK33594.1 - 0.016 15.3 0.1 0.041 14.0 0.1 1.6 1 0 0 1 1 1 0 Podoplanin RasGEF_N_2 PF14663.6 CRK33594.1 - 0.03 14.7 0.2 15 6.0 0.0 2.7 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain VSP PF03302.13 CRK33594.1 - 0.037 12.9 10.5 0.056 12.3 10.5 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein CDC13_N PF16853.5 CRK33594.1 - 0.041 13.4 0.0 11 5.5 0.0 2.2 2 0 0 2 2 2 0 Cell division control protein 13 N-terminus MOR2-PAG1_N PF14222.6 CRK33594.1 - 0.051 12.5 0.0 7.7 5.3 0.0 2.2 2 0 0 2 2 2 0 Cell morphogenesis N-terminal EphA2_TM PF14575.6 CRK33594.1 - 0.052 14.4 0.0 0.11 13.4 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DAP10 PF07213.11 CRK33594.1 - 0.055 13.4 0.2 0.14 12.1 0.2 1.6 1 0 0 1 1 1 0 DAP10 membrane protein SARAF PF06682.12 CRK33594.1 - 0.13 11.9 0.1 0.3 10.7 0.1 1.5 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis CYYR1 PF10873.8 CRK33594.1 - 0.14 12.6 1.6 0.37 11.2 1.6 1.6 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 Adeno_E3_CR2 PF02439.15 CRK33594.1 - 0.19 11.5 2.6 0.42 10.4 2.6 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 LRR_9 PF14580.6 CRK33595.1 - 2.3e-70 235.6 1.6 1.7e-33 115.6 0.0 3.2 2 1 0 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 CRK33595.1 - 7.3e-19 67.6 5.8 2.8e-05 24.4 0.0 5.1 3 2 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CRK33595.1 - 1.3e-15 56.9 1.5 1e-06 28.4 0.0 3.2 3 0 0 3 3 3 2 Leucine rich repeat Gal11_ABD1 PF18535.1 CRK33595.1 - 0.001 19.1 0.2 3 8.0 0.1 2.7 3 0 0 3 3 3 2 Gal11 activator-binding domain (ABD1) DUF4349 PF14257.6 CRK33595.1 - 0.0079 15.7 1.7 0.013 14.9 1.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4349) LRR_6 PF13516.6 CRK33595.1 - 0.012 15.6 5.2 20 5.6 0.0 4.7 5 0 0 5 5 5 0 Leucine Rich repeat PspB PF06667.12 CRK33595.1 - 0.11 12.6 1.0 0.32 11.1 1.0 1.8 1 0 0 1 1 1 0 Phage shock protein B LRR_1 PF00560.33 CRK33595.1 - 0.21 12.3 1.0 1.6e+02 3.5 0.1 4.4 4 1 0 4 4 4 0 Leucine Rich Repeat DUF3652 PF12372.8 CRK33595.1 - 0.69 9.9 2.5 29 4.7 0.2 2.5 2 0 0 2 2 2 0 Huntingtin protein region SERTA PF06031.13 CRK33595.1 - 1.8 8.3 8.1 62 3.4 0.1 4.1 4 0 0 4 4 4 0 SERTA motif Exo84_C PF16528.5 CRK33596.1 - 6.3e-76 254.7 0.9 6.3e-76 254.7 0.9 2.6 3 0 0 3 3 3 1 Exocyst component 84 C-terminal Vps51 PF08700.11 CRK33596.1 - 1e-15 57.5 4.1 1e-15 57.5 4.1 2.9 3 0 0 3 3 3 1 Vps51/Vps67 CBFD_NFYB_HMF PF00808.23 CRK33596.1 - 4.2e-08 33.3 0.3 1.2e-07 31.9 0.3 1.8 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF2383 PF09537.10 CRK33596.1 - 0.009 16.3 3.5 0.28 11.6 1.2 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF2383) COG2 PF06148.11 CRK33596.1 - 0.055 13.6 2.7 1.1 9.4 0.0 3.0 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Tub PF01167.18 CRK33596.1 - 0.059 13.1 0.4 0.13 12.0 0.4 1.5 1 0 0 1 1 1 0 Tub family TSC22 PF01166.18 CRK33596.1 - 0.26 11.6 1.5 29 5.1 0.1 3.4 3 0 0 3 3 3 0 TSC-22/dip/bun family GldM_N PF12081.8 CRK33596.1 - 0.54 10.3 8.1 0.084 13.0 3.2 2.0 2 0 0 2 2 2 0 GldM N-terminal domain CRIC_ras_sig PF10534.9 CRK33596.1 - 1.3 9.2 4.5 40 4.5 0.2 3.6 3 0 0 3 3 3 0 Connector enhancer of kinase suppressor of ras Prominin PF05478.11 CRK33596.1 - 5.3 4.9 9.6 0.19 9.6 2.2 1.9 2 0 0 2 2 2 0 Prominin HMMR_C PF15908.5 CRK33596.1 - 9.5 6.5 9.6 0.89 9.8 3.2 2.5 2 1 1 3 3 3 0 Hyaluronan mediated motility receptor C-terminal MAS20 PF02064.15 CRK33597.1 - 2.1e-41 141.0 1.3 2.6e-41 140.7 1.3 1.0 1 0 0 1 1 1 1 MAS20 protein import receptor DUF347 PF03988.12 CRK33598.1 - 0.42 10.8 3.6 1 9.6 3.6 1.7 1 1 0 1 1 1 0 Repeat of Unknown Function (DUF347) Wyosine_form PF08608.12 CRK33600.1 - 5.5e-27 93.9 0.0 1.1e-26 92.9 0.0 1.5 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.21 CRK33600.1 - 2.1e-25 90.0 0.0 8e-25 88.1 0.0 2.0 2 0 0 2 2 2 1 Radical SAM superfamily Flavodoxin_1 PF00258.25 CRK33600.1 - 2.8e-12 47.0 0.0 1.3e-10 41.6 0.0 2.6 2 0 0 2 2 2 1 Flavodoxin SNF2_N PF00176.23 CRK33601.1 - 3.3e-69 233.2 0.3 4.9e-69 232.7 0.3 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain CDO_I PF05995.12 CRK33601.1 - 3.2e-43 147.0 0.0 6.6e-43 145.9 0.0 1.4 1 0 0 1 1 1 1 Cysteine dioxygenase type I MFS_1 PF07690.16 CRK33601.1 - 2.4e-33 115.5 54.6 4.8e-32 111.3 27.3 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily HIRAN PF08797.11 CRK33601.1 - 6.4e-16 58.1 0.0 1.5e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain SBP_bac_6 PF13343.6 CRK33601.1 - 3e-10 39.9 0.1 7.3e-10 38.7 0.1 1.6 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein zf-C3HC4_2 PF13923.6 CRK33601.1 - 3.2e-10 39.7 11.8 7.4e-10 38.5 11.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CRK33601.1 - 2e-09 37.1 9.8 2e-09 37.1 9.8 2.6 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CRK33601.1 - 7e-08 32.2 12.3 7e-08 32.2 12.3 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) SBP_bac_11 PF13531.6 CRK33601.1 - 8e-08 32.3 0.2 1.5e-07 31.4 0.2 1.4 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein zf-RING_5 PF14634.6 CRK33601.1 - 1.3e-07 31.4 10.7 3e-07 30.3 10.7 1.7 1 0 0 1 1 1 1 zinc-RING finger domain SBP_bac_8 PF13416.6 CRK33601.1 - 6.8e-07 29.4 3.0 6.8e-07 29.4 3.0 1.8 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein zf-RING_2 PF13639.6 CRK33601.1 - 1.4e-06 28.5 11.6 1.4e-06 28.5 11.6 2.2 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 CRK33601.1 - 2.6e-06 27.4 11.6 7.1e-06 25.9 11.6 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 CRK33601.1 - 3.6e-06 27.0 10.8 8.7e-06 25.8 10.8 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING SBP_bac_1 PF01547.25 CRK33601.1 - 6.1e-06 26.4 4.3 1.4e-05 25.2 4.3 1.6 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein Sugar_tr PF00083.24 CRK33601.1 - 2.4e-05 23.4 27.0 8.6e-05 21.6 26.8 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter zf-rbx1 PF12678.7 CRK33601.1 - 0.00059 20.1 8.6 0.0023 18.2 8.6 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 CRK33601.1 - 0.0011 18.8 9.1 0.0034 17.2 9.1 1.9 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 CRK33601.1 - 0.0015 18.4 3.5 0.0051 16.7 3.5 1.9 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 CRK33601.1 - 0.0072 16.4 8.5 0.018 15.2 8.5 1.6 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-Nse PF11789.8 CRK33601.1 - 0.023 14.5 9.5 0.053 13.3 9.5 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 CRK33601.1 - 0.073 13.1 6.5 0.029 14.4 3.2 2.1 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 CRK33601.1 - 0.13 12.1 7.5 0.31 10.9 7.5 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.14 CRK33601.1 - 1.3 8.7 12.6 0.44 10.3 7.6 2.6 2 1 1 3 3 2 0 P-11 zinc finger zinc-ribbons_6 PF07191.12 CRK33601.1 - 2 8.5 6.0 3.9 7.5 6.0 1.5 1 0 0 1 1 1 0 zinc-ribbons Glyco_hydro_61 PF03443.14 CRK33603.1 - 3.7e-51 174.0 0.0 4.9e-51 173.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Ribosomal_L11 PF00298.19 CRK33604.1 - 9.1e-27 93.4 0.0 1.4e-26 92.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 CRK33604.1 - 1.8e-24 85.3 0.0 3.1e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Svf1_C PF17187.4 CRK33605.1 - 1.1e-61 207.5 0.1 5.1e-61 205.3 0.0 1.9 2 0 0 2 2 2 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 CRK33605.1 - 9.2e-55 185.1 0.0 1.3e-54 184.6 0.0 1.2 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain LPD18 PF18832.1 CRK33605.1 - 0.046 13.8 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 18 Acetyltransf_1 PF00583.25 CRK33606.1 - 0.0081 16.4 0.0 0.017 15.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family NOA36 PF06524.12 CRK33608.1 - 0.033 13.5 1.3 0.052 12.9 1.3 1.2 1 0 0 1 1 1 0 NOA36 protein zf-H2C2_2 PF13465.6 CRK33608.1 - 1.2 9.7 5.9 4.2 8.0 2.3 3.2 2 0 0 2 2 2 0 Zinc-finger double domain BRF1 PF07741.13 CRK33623.1 - 1.9e-23 82.7 0.6 3.8e-23 81.7 0.6 1.5 1 0 0 1 1 1 1 Brf1-like TBP-binding domain PhageP22-tail PF09251.10 CRK33623.1 - 0.079 11.3 0.0 0.12 10.7 0.0 1.2 1 0 0 1 1 1 0 Salmonella phage P22 tail-spike DUF3808 PF10300.9 CRK33624.1 - 1.3e-78 264.9 0.0 1.7e-78 264.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) HemY_N PF07219.13 CRK33624.1 - 0.046 13.9 0.3 0.24 11.6 0.0 2.4 2 1 0 2 2 2 0 HemY protein N-terminus TPR_19 PF14559.6 CRK33624.1 - 0.055 14.0 0.8 0.055 14.0 0.8 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_5 PF12688.7 CRK33624.1 - 0.055 13.7 0.1 0.21 11.9 0.1 2.0 1 0 0 1 1 1 0 Tetratrico peptide repeat TPR_4 PF07721.14 CRK33624.1 - 5.5 7.9 12.1 7.1 7.6 3.0 3.8 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4611 PF15387.6 CRK33626.1 - 0.0081 16.4 12.2 0.0081 16.4 12.2 2.7 2 1 1 3 3 3 1 Domain of unknown function (DUF4611) Nop53 PF07767.11 CRK33626.1 - 0.15 11.4 16.9 0.25 10.7 16.9 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) PPL5 PF18168.1 CRK33626.1 - 9.2 5.5 8.4 11 5.1 8.4 1.1 1 0 0 1 1 1 0 Prim-pol family 5 Glyco_hydro_3 PF00933.21 CRK33628.1 - 7.2e-22 78.2 0.0 8.3e-22 78.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain PBP1_TM PF14812.6 CRK33629.1 - 0.099 13.0 3.7 0.14 12.5 3.7 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Glutaminase PF04960.15 CRK33630.1 - 2.1e-32 112.5 0.8 2.7e-32 112.1 0.8 1.2 1 0 0 1 1 1 1 Glutaminase DUF2774 PF11242.8 CRK33630.1 - 0.16 12.2 0.0 0.25 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2774) Apt1 PF10351.9 CRK33631.1 - 2.2e-30 106.0 0.1 2.2e-30 106.0 0.1 1.5 2 0 0 2 2 2 1 Golgi-body localisation protein domain DUF72 PF01904.18 CRK33631.1 - 0.16 12.0 0.0 0.18 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF72 ChAPs PF09295.10 CRK33633.1 - 5.6e-45 154.0 0.1 6.2e-45 153.9 0.1 1.0 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) PknG_TPR PF16918.5 CRK33633.1 - 0.11 11.1 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein kinase G tetratricopeptide repeat 2H-phosphodiest PF08975.10 CRK33638.1 - 0.051 13.5 0.0 0.063 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1868) Vac_Fusion PF02346.16 CRK33638.1 - 0.075 12.7 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Chordopoxvirus multifunctional envelope protein A27 Bax1-I PF01027.20 CRK33641.1 - 8.4e-31 107.4 9.9 9e-31 107.3 9.9 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF5504 PF17608.2 CRK33641.1 - 0.016 15.3 4.7 0.021 14.9 4.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5504) DUF2070 PF09843.9 CRK33641.1 - 1.9 6.7 8.9 2.1 6.5 8.9 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) RhoGAP PF00620.27 CRK33642.1 - 3.6e-42 143.7 0.6 6.2e-42 143.0 0.2 1.5 2 0 0 2 2 2 1 RhoGAP domain Zn_clus PF00172.18 CRK33643.1 - 0.0005 20.1 9.0 0.00079 19.5 9.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 CRK33643.1 - 0.017 14.2 0.1 0.03 13.4 0.1 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain DUF3408 PF11888.8 CRK33643.1 - 0.05 13.7 1.4 7.7 6.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) Zip PF02535.22 CRK33643.1 - 0.49 9.6 1.9 0.76 8.9 1.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.14 CRK33643.1 - 0.63 9.4 13.8 1.1 8.6 13.8 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region SMYLE_N PF18615.1 CRK33643.1 - 1.2 8.6 7.1 2.1 7.8 7.1 1.3 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain DUF2796 PF10986.8 CRK33643.1 - 2 8.4 17.1 3.6 7.5 17.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) RTA1 PF04479.13 CRK33645.1 - 9.1e-56 188.7 0.8 9.1e-56 188.7 0.8 1.5 1 1 1 2 2 2 1 RTA1 like protein Cortexin PF11057.8 CRK33645.1 - 0.36 10.7 1.7 0.45 10.4 0.0 2.0 2 0 0 2 2 2 0 Cortexin of kidney Fungal_trans PF04082.18 CRK33646.1 - 5.5e-11 42.0 0.0 9.9e-11 41.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK33646.1 - 1.8e-09 37.5 8.2 3.3e-09 36.7 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NPP1 PF05630.11 CRK33647.1 - 2.9e-56 190.7 0.0 3.4e-56 190.5 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Oxidored_q6 PF01058.22 CRK33648.1 - 6.5e-23 81.0 0.1 7.5e-23 80.8 0.1 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Secapin PF17521.2 CRK33648.1 - 1.4 8.8 4.4 1.7 8.5 0.2 2.4 1 1 1 2 2 2 0 Honey bee peptides PMT PF02366.18 CRK33651.1 - 2.4e-20 73.2 7.3 2.8e-20 73.0 7.3 1.0 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase RAMP4 PF06624.12 CRK33651.1 - 0.12 12.4 0.2 0.25 11.4 0.2 1.5 1 0 0 1 1 1 0 Ribosome associated membrane protein RAMP4 AMP-binding PF00501.28 CRK33653.1 - 4.3e-22 78.3 0.0 4.6e-22 78.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Sugar_tr PF00083.24 CRK33654.1 - 3.1e-24 85.7 7.9 3.4e-24 85.5 7.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK33654.1 - 5.3e-06 25.6 10.7 5.5e-06 25.6 10.2 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Cytochrom_C1 PF02167.15 CRK33655.1 - 2e-43 148.7 0.0 2.2e-43 148.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 CRK33655.1 - 0.002 18.4 0.1 0.0028 17.9 0.1 1.6 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 CRK33655.1 - 0.12 13.6 0.2 0.18 13.0 0.2 1.6 1 1 0 1 1 1 0 Cytochrome c Glyco_hydro_61 PF03443.14 CRK33661.1 - 1.8e-33 116.3 0.0 2e-33 116.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 SH3_3 PF08239.11 CRK33661.1 - 0.077 13.3 0.2 1.1 9.6 0.2 2.1 1 1 0 1 1 1 0 Bacterial SH3 domain TAL_FSA PF00923.19 CRK33663.1 - 1.3e-42 146.1 0.0 1.6e-42 145.9 0.0 1.1 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase DUF1488 PF07369.11 CRK33663.1 - 0.23 11.4 1.2 0.99 9.4 0.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1488) XPG_N PF00752.17 CRK33665.1 - 8.3e-32 109.7 0.0 2e-31 108.4 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 CRK33665.1 - 6.2e-30 103.4 1.7 1.2e-29 102.5 0.0 2.2 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.20 CRK33665.1 - 8.4e-05 23.1 2.4 0.00023 21.7 0.0 2.6 3 0 0 3 3 3 1 5'-3' exonuclease, C-terminal SAM fold MRPL52 PF18699.1 CRK33665.1 - 6.2 7.1 14.1 2.2 8.5 7.1 3.0 3 0 0 3 3 3 0 Mitoribosomal protein mL52 Acyl-CoA_dh_1 PF00441.24 CRK33666.1 - 5.6e-40 137.0 0.3 8.5e-40 136.4 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 CRK33666.1 - 2.8e-22 78.7 0.1 4.6e-22 78.0 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 CRK33666.1 - 7.9e-21 74.0 0.4 1.4e-20 73.2 0.4 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 CRK33666.1 - 8.4e-16 58.6 0.0 1.8e-15 57.6 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 CRK33666.1 - 3.9e-07 30.4 0.0 6.4e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain PXPV PF12778.7 CRK33666.1 - 6.7 6.7 11.3 12 5.9 11.3 1.4 1 0 0 1 1 1 0 PXPV repeat (3 copies) Acyl-CoA_dh_1 PF00441.24 CRK33667.1 - 7e-40 136.7 0.3 1.1e-39 136.0 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 CRK33667.1 - 3e-22 78.6 0.1 5.4e-22 77.8 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 CRK33667.1 - 3.4e-07 30.6 0.0 6e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CRK33667.1 - 0.00021 21.9 0.0 0.00048 20.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain LIN52 PF10044.9 CRK33668.1 - 0.16 12.7 0.1 0.29 11.9 0.1 1.5 1 1 1 2 2 2 0 Retinal tissue protein Transket_pyr PF02779.24 CRK33669.1 - 1.6e-21 76.8 0.0 1.9e-21 76.5 0.0 1.1 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain DUF1077 PF06417.12 CRK33670.1 - 4.1e-48 162.3 6.2 4.6e-48 162.1 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) NAD_binding_8 PF13450.6 CRK33671.1 - 2.4e-06 27.7 0.0 3.5e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain PPR_2 PF13041.6 CRK33673.1 - 1.6e-08 34.6 0.0 8.5e-05 22.7 0.0 2.6 1 1 1 2 2 2 2 PPR repeat family PPR_1 PF12854.7 CRK33673.1 - 6.6e-08 32.1 0.0 6.5e-05 22.5 0.0 2.6 2 0 0 2 2 2 2 PPR repeat PPR_3 PF13812.6 CRK33673.1 - 1.1e-06 28.6 0.0 5.2e-06 26.4 0.0 2.1 2 0 0 2 2 2 1 Pentatricopeptide repeat domain PPR_long PF17177.4 CRK33673.1 - 0.0057 16.0 0.0 0.013 14.8 0.0 1.6 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 CRK33673.1 - 0.0091 16.2 0.0 0.17 12.2 0.0 3.0 3 0 0 3 3 3 1 PPR repeat SpoIIIAC PF06686.11 CRK33673.1 - 0.037 14.2 0.1 0.071 13.3 0.1 1.5 1 0 0 1 1 1 0 Stage III sporulation protein AC/AD protein family MitMem_reg PF13012.6 CRK33674.1 - 3.3e-18 66.1 0.5 1.4e-17 64.1 0.0 2.2 3 0 0 3 3 3 1 Maintenance of mitochondrial structure and function JAB PF01398.21 CRK33674.1 - 5.1e-16 58.7 0.0 9e-16 57.9 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Ribosomal_L17 PF01196.19 CRK33674.1 - 2.7e-15 57.0 0.0 6.4e-15 55.8 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein L17 AIM5 PF17050.5 CRK33676.1 - 4.6e-23 81.8 4.8 1.6e-22 80.1 0.9 2.8 2 0 0 2 2 2 1 Altered inheritance of mitochondria 5 UBA_4 PF14555.6 CRK33676.1 - 0.12 12.2 0.2 0.42 10.5 0.2 1.9 1 0 0 1 1 1 0 UBA-like domain Cyt-b5 PF00173.28 CRK33678.1 - 6.1e-06 26.3 0.0 8.1e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TRP PF06011.12 CRK33681.1 - 4.5e-37 127.8 4.6 5.3e-37 127.6 4.6 1.0 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel Sulfate_transp PF00916.20 CRK33692.1 - 2.3e-18 66.1 0.8 2.3e-18 66.1 0.8 1.4 2 0 0 2 2 2 1 Sulfate permease family VirB3 PF05101.13 CRK33692.1 - 0.08 13.2 5.8 0.74 10.1 0.1 2.1 2 0 0 2 2 2 0 Type IV secretory pathway, VirB3-like protein YdjM PF04307.14 CRK33692.1 - 0.3 10.4 4.6 0.39 10.0 4.6 1.1 1 0 0 1 1 1 0 LexA-binding, inner membrane-associated putative hydrolase Bombesin PF02044.17 CRK33692.1 - 0.55 10.4 2.3 0.73 10.0 1.5 1.7 2 0 0 2 2 2 0 Bombesin-like peptide DUF1700 PF08006.11 CRK33692.1 - 1.1 8.7 5.8 1.3 8.5 5.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) His_Phos_1 PF00300.22 CRK33694.1 - 7.8e-33 113.8 0.0 1.1e-32 113.3 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Asp PF00026.23 CRK33694.1 - 1.9e-06 27.5 0.1 2.7e-06 27.1 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Peptidase_M20 PF01546.28 CRK33699.1 - 1.7e-21 76.8 0.0 2e-21 76.6 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 CAF1A PF12253.8 CRK33700.1 - 2e-07 31.1 11.7 3.1e-07 30.5 11.7 1.3 1 0 0 1 1 1 1 Chromatin assembly factor 1 subunit A Choline_transpo PF04515.12 CRK33701.1 - 3.8e-05 23.1 0.2 4.5e-05 22.8 0.2 1.0 1 0 0 1 1 1 1 Plasma-membrane choline transporter KH_1 PF00013.29 CRK33703.1 - 5e-23 80.7 2.1 1.3e-10 41.0 0.1 2.3 2 1 0 2 2 2 2 KH domain KH_2 PF07650.17 CRK33703.1 - 3.7e-05 23.4 0.1 0.0058 16.4 0.0 2.3 2 0 0 2 2 2 2 KH domain SLS PF14611.6 CRK33703.1 - 0.022 14.6 0.0 0.069 13.0 0.0 2.0 1 1 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator KH_4 PF13083.6 CRK33703.1 - 0.035 14.0 0.1 3.8 7.4 0.0 2.4 2 1 0 2 2 2 0 KH domain MutS_III PF05192.18 CRK33705.1 - 1.7e-27 96.9 0.1 1.8e-27 96.9 0.1 1.0 1 0 0 1 1 1 1 MutS domain III Peptidase_M16 PF00675.20 CRK33705.1 - 0.046 13.7 0.1 0.053 13.5 0.1 1.2 1 0 0 1 1 1 0 Insulinase (Peptidase family M16) Sigma70_r2 PF04542.14 CRK33705.1 - 0.064 13.0 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Sigma-70 region 2 Methyltransf_25 PF13649.6 CRK33706.1 - 5e-05 23.9 0.0 9.2e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CRK33706.1 - 7.9e-05 23.2 0.0 0.00021 21.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 CRK33706.1 - 0.0092 15.7 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Lipin_N PF04571.14 CRK33709.1 - 4.7e-44 148.5 0.0 5.5e-44 148.3 0.0 1.0 1 0 0 1 1 1 1 lipin, N-terminal conserved region Ank_4 PF13637.6 CRK33710.1 - 1.9e-18 66.6 0.4 1.5e-08 35.0 0.0 4.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 CRK33710.1 - 8.6e-15 55.1 0.3 1.7e-11 44.5 0.1 2.7 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CRK33710.1 - 2.3e-14 52.0 0.2 0.00036 20.7 0.0 5.0 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 CRK33710.1 - 8.7e-13 48.1 4.0 0.011 16.2 0.1 4.3 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 CRK33710.1 - 2.8e-11 43.4 0.7 0.0028 17.9 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) MOZART1 PF12554.8 CRK33710.1 - 0.11 12.3 0.2 24 4.8 0.0 2.9 3 0 0 3 3 3 0 Mitotic-spindle organizing gamma-tubulin ring associated FLgD_tudor PF13861.6 CRK33710.1 - 0.12 12.6 0.0 0.25 11.6 0.0 1.6 1 1 1 2 2 2 0 FlgD Tudor-like domain Phage_T7_Capsid PF05396.11 CRK33710.1 - 0.22 11.9 0.2 5.6 7.4 0.0 2.1 1 1 1 2 2 2 0 Phage T7 capsid assembly protein Fib_alpha PF08702.10 CRK33711.1 - 0.029 14.6 0.1 0.029 14.5 0.1 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF2048 PF09752.9 CRK33711.1 - 0.1 11.7 0.0 0.11 11.5 0.0 1.0 1 0 0 1 1 1 0 Abhydrolase domain containing 18 Plug_translocon PF10559.9 CRK33712.1 - 5e-17 61.4 0.3 8.9e-17 60.6 0.3 1.4 1 0 0 1 1 1 1 Plug domain of Sec61p SecY PF00344.20 CRK33712.1 - 0.00037 19.8 0.1 0.00054 19.3 0.1 1.3 1 0 0 1 1 1 1 SecY translocase Fungal_trans PF04082.18 CRK33712.1 - 0.0011 18.0 0.0 0.0057 15.7 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Aldo_ket_red PF00248.21 CRK33713.1 - 1.2e-13 51.0 0.0 1.2e-13 51.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FAD_binding_4 PF01565.23 CRK33715.1 - 4.7e-22 78.2 0.0 5.6e-22 78.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain SepSecS PF05889.13 CRK33715.1 - 0.0044 15.8 0.0 0.0076 15.0 0.0 1.4 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS ANF_receptor PF01094.28 CRK33715.1 - 0.0066 15.6 0.0 0.0081 15.3 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Glyco_transf_64 PF09258.10 CRK33716.1 - 5.5e-23 81.5 0.0 5.9e-23 81.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Response_reg PF00072.24 CRK33720.1 - 5.1e-19 68.5 0.1 6e-19 68.3 0.1 1.1 1 0 0 1 1 1 1 Response regulator receiver domain Glyco_hydro_76 PF03663.14 CRK33723.1 - 9.1e-50 170.2 1.9 1e-49 170.0 1.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 DnaJ_C PF01556.18 CRK33726.1 - 3.8e-06 27.0 0.0 4.8e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain Helicase_C PF00271.31 CRK33727.1 - 1.2e-11 44.9 0.0 1.3e-11 44.8 0.0 1.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 CRK33727.1 - 0.0029 16.9 0.0 0.004 16.4 0.0 1.1 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DEP PF00610.21 CRK33728.1 - 1.5e-12 47.4 0.0 2e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) YppG PF14179.6 CRK33729.1 - 0.086 13.6 4.8 0.11 13.3 4.8 1.1 1 0 0 1 1 1 0 YppG-like protein FAT PF02259.23 CRK33730.1 - 2.5e-131 438.0 10.4 4.7e-131 437.1 10.4 1.5 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 CRK33730.1 - 2.2e-73 247.2 0.1 3.8e-73 246.4 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 CRK33730.1 - 1.8e-70 236.0 4.8 2.7e-67 225.7 0.3 5.2 5 0 0 5 5 5 1 Domain of unknown function (DUF3385) FRB_dom PF08771.11 CRK33730.1 - 2.2e-46 156.3 0.2 1.7e-45 153.4 0.2 2.7 1 0 0 1 1 1 1 FKBP12-rapamycin binding domain HEAT PF02985.22 CRK33730.1 - 9.6e-15 53.4 15.3 0.00032 20.7 0.0 11.5 11 0 0 11 11 11 2 HEAT repeat HEAT_2 PF13646.6 CRK33730.1 - 1.1e-13 51.4 15.8 7.7e-05 23.0 0.1 8.5 8 2 1 9 9 9 3 HEAT repeats HEAT_EZ PF13513.6 CRK33730.1 - 6.1e-12 45.8 12.6 2.6e-05 24.6 0.1 10.0 8 3 3 11 11 10 3 HEAT-like repeat Cnd1 PF12717.7 CRK33730.1 - 1.2e-06 28.6 0.4 4 7.5 0.0 5.9 3 1 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 CRK33730.1 - 2.7e-05 23.0 3.9 2.2 6.7 0.0 5.2 3 2 1 4 4 4 2 Adaptin N terminal region ParcG PF10274.9 CRK33730.1 - 0.0072 16.5 5.8 1.7 8.8 0.0 5.4 5 1 1 6 6 6 1 Parkin co-regulated protein RIX1 PF08167.12 CRK33730.1 - 0.013 15.3 0.6 1.5 8.5 0.0 3.9 3 0 0 3 3 3 0 rRNA processing/ribosome biogenesis PRKCSH-like PF12999.7 CRK33731.1 - 1.6e-42 145.3 7.0 7.2e-25 87.8 1.4 3.1 2 1 1 3 3 3 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 CRK33731.1 - 1.4e-31 109.3 0.4 1.4e-31 109.3 0.4 1.8 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 CRK33731.1 - 9.9e-10 39.3 0.9 3.4e-09 37.6 0.9 2.0 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein ATG27 PF09451.10 CRK33731.1 - 0.004 17.1 0.6 0.0091 15.9 0.6 1.6 1 0 0 1 1 1 1 Autophagy-related protein 27 Snapin_Pallidin PF14712.6 CRK33731.1 - 0.032 14.6 0.1 0.032 14.6 0.1 2.3 3 0 0 3 3 2 0 Snapin/Pallidin Ish1 PF10281.9 CRK33731.1 - 0.035 14.4 0.0 0.14 12.5 0.0 2.1 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein Mod_r PF07200.13 CRK33731.1 - 0.061 13.4 0.6 0.061 13.4 0.6 3.1 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein CdAMP_rec PF06153.11 CRK33731.1 - 0.099 12.9 0.9 3.3 8.0 0.0 2.7 2 1 1 3 3 3 0 Cyclic-di-AMP receptor DUF1664 PF07889.12 CRK33731.1 - 0.18 11.9 2.6 0.75 9.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF3086 PF11285.8 CRK33731.1 - 0.19 10.8 0.1 0.19 10.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3086) Fib_alpha PF08702.10 CRK33731.1 - 0.28 11.4 4.2 0.59 10.3 0.1 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.12 CRK33731.1 - 0.31 11.5 1.0 8.1 7.0 0.0 2.8 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein YabA PF06156.13 CRK33731.1 - 0.39 11.4 7.1 3.1 8.5 0.1 2.6 2 0 0 2 2 2 0 Initiation control protein YabA Prefoldin_2 PF01920.20 CRK33731.1 - 2.4 8.2 17.8 2.6 8.0 3.6 3.8 3 1 0 3 3 3 0 Prefoldin subunit DUF2721 PF11026.8 CRK33731.1 - 3.2 7.7 5.0 1 9.2 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) H-kinase_dim PF02895.14 CRK33731.1 - 3.4 8.1 5.8 4.2 7.8 0.1 2.7 3 0 0 3 3 2 0 Signal transducing histidine kinase, homodimeric domain CCCAP PF15964.5 CRK33731.1 - 4 5.6 14.4 8.1 4.6 14.4 1.5 1 1 0 1 1 1 0 Centrosomal colon cancer autoantigen protein family Taxilin PF09728.9 CRK33731.1 - 5.3 6.1 16.9 1.7 7.7 8.3 2.4 3 0 0 3 3 3 0 Myosin-like coiled-coil protein Filament PF00038.21 CRK33731.1 - 5.5 6.5 21.8 0.91 9.0 8.9 2.4 2 1 0 2 2 2 0 Intermediate filament protein Spc7 PF08317.11 CRK33731.1 - 8.1 5.2 16.9 2.2 7.1 0.4 3.0 3 0 0 3 3 3 0 Spc7 kinetochore protein CALCOCO1 PF07888.11 CRK33731.1 - 8.2 5.2 19.5 0.78 8.5 1.2 2.3 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like ECM11 PF15463.6 CRK33731.1 - 9.7 6.8 10.4 0.69 10.5 0.4 2.5 2 0 0 2 2 2 0 Extracellular mutant protein 11 zf-CpG_bind_C PF12269.8 CRK33731.1 - 9.9 5.9 10.6 21 4.8 0.1 2.6 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain Peptidase_M28 PF04389.17 CRK33732.1 - 4.3e-27 95.1 0.5 5.7e-26 91.4 0.5 2.1 1 1 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 CRK33732.1 - 8.6e-06 25.6 0.2 2.6e-05 24.0 0.2 1.8 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.15 CRK33732.1 - 0.054 12.9 0.1 0.14 11.6 0.0 1.7 2 0 0 2 2 2 0 Nicastrin CW_7 PF08230.11 CRK33732.1 - 0.18 11.6 0.2 0.37 10.6 0.2 1.4 1 0 0 1 1 1 0 CW_7 repeat FAD_binding_3 PF01494.19 CRK33733.1 - 2.9e-31 109.0 0.2 3.8e-31 108.6 0.2 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 CRK33733.1 - 6.9e-12 45.6 1.1 2.1e-05 24.3 0.1 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CRK33733.1 - 1.8e-09 37.3 0.3 0.0019 17.5 0.0 2.4 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CRK33733.1 - 8e-07 29.5 0.2 0.00067 20.2 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 CRK33733.1 - 2.2e-05 23.5 3.2 0.011 14.6 0.2 2.9 2 1 1 3 3 3 2 Tryptophan halogenase NAD_binding_8 PF13450.6 CRK33733.1 - 0.0001 22.4 0.1 0.00032 20.9 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 CRK33733.1 - 0.0009 18.6 0.0 0.003 16.9 0.0 1.7 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 CRK33733.1 - 0.001 17.9 0.1 0.59 8.8 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 CRK33733.1 - 0.0032 16.6 0.1 0.01 15.0 0.0 1.7 1 1 1 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 CRK33733.1 - 0.0035 16.7 0.2 0.0049 16.2 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 CRK33733.1 - 0.0047 16.1 0.1 0.0062 15.7 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 CRK33733.1 - 0.012 14.8 0.0 1.4 8.1 0.0 2.3 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 CRK33733.1 - 0.014 15.1 0.1 0.025 14.2 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 CRK33733.1 - 0.063 13.3 0.0 0.2 11.6 0.0 1.8 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus SE PF08491.10 CRK33733.1 - 0.21 10.6 0.0 0.48 9.4 0.0 1.6 2 0 0 2 2 2 0 Squalene epoxidase Sugar_tr PF00083.24 CRK33734.1 - 7.7e-123 410.7 21.0 8.8e-123 410.5 21.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK33734.1 - 7.4e-20 71.2 30.9 7.4e-20 71.2 30.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.9 CRK33734.1 - 8.8 6.6 7.8 1.3 9.3 0.7 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) Ribonuc_L-PSP PF01042.21 CRK33735.1 - 1e-16 61.0 0.0 1.2e-16 60.8 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Methyltransf_23 PF13489.6 CRK33737.1 - 4.6e-21 75.4 0.0 7.9e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK33737.1 - 9.2e-13 48.2 0.0 1.1e-11 44.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK33737.1 - 5.9e-11 42.9 0.0 1.5e-10 41.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CRK33737.1 - 7.7e-09 36.1 0.0 1.5e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK33737.1 - 1.5e-07 32.0 0.0 1e-06 29.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 CRK33737.1 - 0.0013 18.3 0.0 0.0055 16.2 0.0 1.8 2 0 0 2 2 2 1 CheR methyltransferase, SAM binding domain MTS PF05175.14 CRK33737.1 - 0.004 16.7 0.0 0.0079 15.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 CRK33737.1 - 0.0078 15.7 0.0 0.018 14.5 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.19 CRK33737.1 - 0.012 15.7 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase PrmA PF06325.13 CRK33737.1 - 0.052 12.9 0.0 0.077 12.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 CRK33737.1 - 0.15 11.8 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase DUF1989 PF09347.10 CRK33738.1 - 2.6e-51 173.6 0.1 2.7e-49 167.0 0.1 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF1989) Acetyltransf_1 PF00583.25 CRK33739.1 - 7.9e-05 22.9 0.1 0.00022 21.4 0.1 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 CRK33739.1 - 0.0011 18.9 0.0 0.0041 17.1 0.0 1.9 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_10 PF13673.7 CRK33739.1 - 0.0024 17.8 0.0 0.0042 17.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CRK33739.1 - 0.0025 18.2 0.4 0.0055 17.1 0.1 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Zn_clus PF00172.18 CRK33740.1 - 5.6e-06 26.4 10.4 1.1e-05 25.5 10.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mito_carr PF00153.27 CRK33741.1 - 6.9e-48 160.5 2.4 1.3e-17 63.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PT-VENN PF04829.13 CRK33741.1 - 7.4 6.7 7.1 2.4 8.3 0.5 2.7 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif DALR_2 PF09190.11 CRK33742.1 - 0.036 14.6 0.2 2.8 8.5 0.0 2.6 3 0 0 3 3 3 0 DALR domain CoA_trans PF01144.23 CRK33743.1 - 1.9e-94 315.1 1.9 1.5e-57 194.5 0.0 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 CRK33743.1 - 0.0035 17.3 0.2 0.0069 16.3 0.2 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Mal_decarbox_Al PF16957.5 CRK33743.1 - 0.036 12.4 0.6 0.23 9.8 0.0 1.9 2 0 0 2 2 2 0 Malonate decarboxylase, alpha subunit, transporter DUF755 PF05501.11 CRK33744.1 - 0.16 12.3 17.5 0.24 11.7 17.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) SH3_2 PF07653.17 CRK33745.1 - 0.00016 21.3 0.1 0.00036 20.2 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 CRK33745.1 - 0.0002 21.1 0.2 0.00057 19.7 0.2 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CRK33745.1 - 0.015 14.9 1.2 0.031 13.9 1.2 1.5 1 0 0 1 1 1 0 SH3 domain zf-H2C2_2 PF13465.6 CRK33745.1 - 3.4 8.3 7.2 6.7 7.3 1.4 3.5 3 0 0 3 3 3 0 Zinc-finger double domain Dynamin_N PF00350.23 CRK33747.1 - 3.6e-12 46.7 1.7 4.9e-11 43.0 0.0 3.5 1 1 1 2 2 2 1 Dynamin family ABC_tran PF00005.27 CRK33747.1 - 2.9e-06 27.8 3.1 0.00016 22.2 0.0 2.8 2 1 0 2 2 2 1 ABC transporter MMR_HSR1 PF01926.23 CRK33747.1 - 9.2e-06 25.7 0.5 0.029 14.4 0.0 3.0 2 1 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CRK33747.1 - 0.02 14.8 0.8 0.074 12.9 0.0 2.3 2 1 0 2 2 2 0 RsgA GTPase IIGP PF05049.13 CRK33747.1 - 0.026 13.6 2.2 0.22 10.5 0.0 2.8 3 0 0 3 3 3 0 Interferon-inducible GTPase (IIGP) cobW PF02492.19 CRK33747.1 - 0.026 14.1 0.1 0.097 12.2 0.1 2.0 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 CRK33747.1 - 0.027 14.9 0.9 0.14 12.5 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.6 CRK33747.1 - 0.086 13.4 3.8 0.4 11.2 0.0 3.2 3 0 0 3 3 3 0 AAA domain GTP_EFTU PF00009.27 CRK33747.1 - 0.41 10.1 5.8 18 4.8 0.0 3.1 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Herpes_UL3 PF03369.13 CRK33747.1 - 0.96 10.0 6.3 0.49 10.9 3.5 1.9 1 1 1 2 2 2 0 Herpesvirus UL3 protein DUF724 PF05266.14 CRK33747.1 - 7.1 6.4 15.0 69 3.2 13.7 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF724) TMPIT PF07851.13 CRK33747.1 - 8.1 5.6 8.7 14 4.8 8.7 1.3 1 0 0 1 1 1 0 TMPIT-like protein MFS_1 PF07690.16 CRK33748.1 - 2.6e-41 141.7 24.3 2.6e-41 141.7 24.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily PhaG_MnhG_YufB PF03334.14 CRK33748.1 - 2.8 8.2 11.4 5.9 7.2 4.4 3.4 3 0 0 3 3 3 0 Na+/H+ antiporter subunit MFS_1 PF07690.16 CRK33749.1 - 2.3e-23 82.7 44.3 2.1e-17 63.1 23.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily JAMP PF05571.12 CRK33749.1 - 1.4 8.5 9.5 0.044 13.4 3.3 1.6 2 0 0 2 2 2 0 JNK1/MAPK8-associated membrane protein Thiolase_N PF00108.23 CRK33750.1 - 2.5e-67 227.0 1.5 3.5e-67 226.5 1.5 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CRK33750.1 - 1.3e-39 134.7 0.5 3.3e-39 133.3 0.5 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain TRI12 PF06609.13 CRK33751.1 - 2.9e-53 181.2 12.2 3.5e-53 180.9 12.2 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 CRK33751.1 - 1.1e-15 57.4 25.2 4.1e-15 55.6 24.2 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Aminotran_3 PF00202.21 CRK33752.1 - 2.2e-87 293.4 0.0 2.7e-87 293.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Pex24p PF06398.11 CRK33754.1 - 3.7e-91 305.8 0.7 5.1e-91 305.4 0.7 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Fungal_trans PF04082.18 CRK33755.1 - 3.7e-07 29.4 1.5 3.7e-07 29.4 1.5 2.3 2 1 0 2 2 2 1 Fungal specific transcription factor domain adh_short PF00106.25 CRK33756.1 - 2e-11 43.7 0.2 1.2e-06 28.1 0.0 3.1 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CRK33756.1 - 0.00028 20.5 0.1 0.088 12.3 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK33756.1 - 0.0077 16.2 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 CRK33756.1 - 0.078 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein SOR_SNZ PF01680.17 CRK33757.1 - 1.1e-102 342.2 7.4 1.4e-102 341.8 7.4 1.1 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 CRK33757.1 - 6.1e-09 35.5 9.0 2.2e-07 30.5 1.1 2.6 2 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG TetR_C_27 PF17935.1 CRK33757.1 - 0.00082 19.4 0.0 0.0033 17.5 0.0 1.9 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain Dus PF01207.17 CRK33757.1 - 0.0011 18.2 0.6 0.31 10.1 0.0 2.5 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 CRK33757.1 - 0.0017 17.8 0.7 0.057 12.9 0.0 2.7 3 0 0 3 3 3 1 Histidine biosynthesis protein NanE PF04131.14 CRK33757.1 - 0.023 13.9 0.9 0.23 10.6 0.0 2.7 1 1 1 3 3 3 0 Putative N-acetylmannosamine-6-phosphate epimerase IGPS PF00218.21 CRK33757.1 - 0.055 12.6 0.1 0.87 8.7 0.0 2.6 2 2 0 2 2 2 0 Indole-3-glycerol phosphate synthase NMO PF03060.15 CRK33757.1 - 0.88 8.9 11.6 0.15 11.4 3.3 2.2 2 0 0 2 2 2 0 Nitronate monooxygenase SNO PF01174.19 CRK33758.1 - 9.7e-33 113.6 0.0 3.4e-29 102.0 0.0 2.9 1 1 1 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 CRK33758.1 - 0.0038 16.9 0.0 0.029 14.0 0.0 1.9 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain TMEM135_C_rich PF15982.5 CRK33759.1 - 0.035 14.7 0.3 0.089 13.4 0.1 1.7 2 0 0 2 2 2 0 N-terminal cysteine-rich region of Transmembrane protein 135 UQ_con PF00179.26 CRK33760.1 - 1.7e-19 69.9 0.0 3.2e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Bac_surface_Ag PF01103.23 CRK33761.1 - 3.7e-33 115.4 0.0 4.9e-33 115.0 0.0 1.2 1 0 0 1 1 1 1 Surface antigen Glyco_hydro_76 PF03663.14 CRK33762.1 - 6.2e-150 499.8 7.6 7.1e-150 499.6 7.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Bac_surface_Ag PF01103.23 CRK33763.1 - 2.1e-13 50.4 0.1 2.6e-13 50.2 0.1 1.1 1 0 0 1 1 1 1 Surface antigen Glyco_hydro_76 PF03663.14 CRK33764.1 - 6.8e-150 499.6 7.7 7.9e-150 499.4 7.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 ABC2_membrane PF01061.24 CRK33765.1 - 6.4e-93 310.0 54.1 7e-48 162.8 24.3 2.5 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 CRK33765.1 - 2.5e-18 66.9 0.0 1.2e-09 38.9 0.0 2.9 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 CRK33765.1 - 3.3e-10 39.7 1.4 1e-06 28.5 0.1 4.6 5 0 0 5 5 5 2 CDR ABC transporter AAA_25 PF13481.6 CRK33765.1 - 0.0031 17.1 0.0 0.0054 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 CRK33765.1 - 0.01 15.8 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 CRK33765.1 - 0.014 15.1 0.3 0.032 14.0 0.3 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 CRK33765.1 - 0.018 15.4 0.0 0.034 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 CRK33765.1 - 0.022 14.9 0.0 0.051 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CRK33765.1 - 0.033 14.8 0.0 0.061 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 CRK33765.1 - 0.038 13.6 0.1 0.083 12.5 0.1 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 CRK33765.1 - 0.066 13.7 0.1 0.13 12.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain VEK-30 PF12107.8 CRK33765.1 - 0.18 11.7 0.5 0.4 10.6 0.5 1.6 1 0 0 1 1 1 0 Plasminogen (Pg) ligand in fibrinolytic pathway AAA_22 PF13401.6 CRK33765.1 - 0.19 12.0 0.0 0.4 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_trans_N PF14510.6 CRK33766.1 - 4e-17 62.6 1.0 2.1e-16 60.3 1.0 2.3 2 1 0 2 2 2 1 ABC-transporter N-terminal ABC_tran PF00005.27 CRK33766.1 - 1.1e-13 51.9 0.0 4.4e-13 49.9 0.0 1.9 1 1 1 2 2 2 1 ABC transporter Vint PF14623.6 CRK33767.1 - 1.6e-65 220.0 0.0 3.4e-65 218.9 0.0 1.6 1 0 0 1 1 1 1 Hint-domain Vwaint PF14624.6 CRK33767.1 - 6.4e-24 83.9 0.0 1.2e-23 83.0 0.0 1.4 1 0 0 1 1 1 1 VWA / Hh protein intein-like VWA PF00092.28 CRK33767.1 - 1.9e-16 60.8 0.0 3.9e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 CRK33767.1 - 1.2e-12 48.1 0.0 3.4e-10 40.1 0.0 2.7 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.6 CRK33767.1 - 3.8e-11 43.6 0.0 8e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 CRK33767.1 - 0.021 14.2 0.0 0.069 12.5 0.0 1.8 2 0 0 2 2 2 0 VWA domain containing CoxE-like protein Hint PF01079.20 CRK33767.1 - 0.15 11.6 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Hint module Hom_end_hint PF05203.16 CRK33767.1 - 0.18 11.8 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 Hom_end-associated Hint MFS_1 PF07690.16 CRK33768.1 - 8.8e-36 123.5 26.9 5.8e-35 120.9 28.4 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4027 PF13219.6 CRK33768.1 - 7.9 6.4 7.3 0.97 9.4 2.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4027) TPP_enzyme_N PF02776.18 CRK33769.1 - 2e-28 99.1 2.7 7.3e-28 97.3 2.7 2.0 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Fungal_trans PF04082.18 CRK33769.1 - 4.8e-18 65.1 0.7 8.1e-18 64.4 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain TPP_enzyme_C PF02775.21 CRK33769.1 - 2.2e-14 53.5 0.1 6.2e-14 52.1 0.1 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 CRK33769.1 - 9e-08 31.9 0.0 1.7e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain DUF1929 PF09118.11 CRK33770.1 - 1.2e-23 83.2 0.1 2.8e-23 82.0 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_6 PF13964.6 CRK33770.1 - 3.9e-16 58.7 0.0 0.00054 20.2 0.0 4.2 3 0 0 3 3 3 3 Kelch motif PAN_1 PF00024.26 CRK33770.1 - 1.1e-14 54.2 9.8 2.6e-07 30.5 2.1 2.4 2 0 0 2 2 2 2 PAN domain Kelch_1 PF01344.25 CRK33770.1 - 7.6e-12 44.6 0.0 0.0083 15.7 0.0 3.8 3 0 0 3 3 3 3 Kelch motif Kelch_4 PF13418.6 CRK33770.1 - 1.3e-07 31.5 5.5 0.00031 20.7 0.0 5.3 5 0 0 5 5 5 1 Galactose oxidase, central domain Glyoxal_oxid_N PF07250.11 CRK33770.1 - 8.8e-07 28.4 0.0 0.049 12.8 0.0 3.1 2 1 0 2 2 2 2 Glyoxal oxidase N-terminus Kelch_2 PF07646.15 CRK33770.1 - 2.9e-05 23.8 0.0 0.72 9.9 0.0 4.7 4 0 0 4 4 4 1 Kelch motif PAN_4 PF14295.6 CRK33770.1 - 5.6e-05 23.0 14.2 0.0085 16.0 1.7 2.6 2 0 0 2 2 2 2 PAN domain MANEC PF07502.14 CRK33770.1 - 0.005 17.1 8.6 0.13 12.5 2.3 2.4 2 0 0 2 2 2 2 MANEC domain Kelch_3 PF13415.6 CRK33770.1 - 0.0053 17.0 0.5 0.083 13.2 0.1 3.3 3 0 0 3 3 3 1 Galactose oxidase, central domain PAN_3 PF08277.12 CRK33770.1 - 4 7.3 9.6 17 5.3 3.3 2.5 2 0 0 2 2 2 0 PAN-like domain MFS_1 PF07690.16 CRK33771.1 - 2.9e-17 62.6 32.9 5.6e-13 48.5 23.5 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK33771.1 - 0.0047 15.9 0.2 0.0047 15.9 0.2 3.6 3 1 1 4 4 4 2 Sugar (and other) transporter NPP1 PF05630.11 CRK33772.1 - 1.3e-51 175.5 0.2 1.7e-51 175.1 0.2 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) LRR_8 PF13855.6 CRK33773.1 - 8.5e-32 108.7 46.9 2.2e-06 27.3 0.0 8.5 4 2 3 8 8 8 8 Leucine rich repeat LRR_4 PF12799.7 CRK33773.1 - 9.7e-25 86.2 46.0 0.0003 21.1 0.6 10.1 6 2 6 12 12 12 10 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CRK33773.1 - 7.2e-06 25.6 24.2 0.075 12.5 2.9 5.9 2 2 4 6 6 6 5 Leucine-rich repeat LRR_6 PF13516.6 CRK33773.1 - 9.7e-05 22.1 32.8 3.5 7.9 0.0 11.1 13 0 0 13 13 13 3 Leucine Rich repeat LRR_1 PF00560.33 CRK33773.1 - 0.0029 17.9 29.5 36 5.5 0.7 12.0 12 2 1 13 13 13 0 Leucine Rich Repeat DUF2322 PF10084.9 CRK33773.1 - 0.042 13.9 0.0 1.6 8.8 0.0 3.1 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2322) Sugar_tr PF00083.24 CRK33776.1 - 3.8e-71 240.3 22.9 4.7e-71 240.0 22.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK33776.1 - 8.5e-16 57.8 29.8 8.5e-16 57.8 29.8 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 CRK33776.1 - 0.0021 17.0 3.4 0.0021 17.0 3.4 1.9 2 0 0 2 2 2 1 MFS_1 like family GLEYA PF10528.9 CRK33777.1 - 2.6e-28 98.3 0.2 7e-28 96.9 0.2 1.8 1 0 0 1 1 1 1 GLEYA domain PA14 PF07691.12 CRK33777.1 - 0.00014 21.7 0.0 0.00027 20.8 0.0 1.5 1 0 0 1 1 1 1 PA14 domain SnoaL_2 PF12680.7 CRK33778.1 - 7.3e-07 29.8 0.0 9.9e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 CRK33778.1 - 0.0011 18.8 0.0 0.32 10.8 0.0 2.1 2 0 0 2 2 2 2 SnoaL-like polyketide cyclase Zn_clus PF00172.18 CRK33779.1 - 3.4e-06 27.1 12.2 5.4e-06 26.4 12.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 CRK33779.1 - 0.00049 19.0 0.1 0.0025 16.7 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain CAP PF00188.26 CRK33780.1 - 1.8e-19 70.8 1.8 3.7e-19 69.8 1.8 1.5 1 1 0 1 1 1 1 Cysteine-rich secretory protein family Lipase_GDSL_2 PF13472.6 CRK33781.1 - 8.9e-13 49.0 0.9 1.1e-12 48.7 0.9 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 CRK33781.1 - 6.8e-06 26.2 0.0 9.5e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase PhageMin_Tail PF10145.9 CRK33781.1 - 0.11 12.4 3.0 0.17 11.7 3.0 1.2 1 0 0 1 1 1 0 Phage-related minor tail protein peroxidase PF00141.23 CRK33782.1 - 8.2e-82 274.3 0.0 7.3e-43 146.9 0.0 2.3 2 0 0 2 2 2 2 Peroxidase Cellulase PF00150.18 CRK33785.1 - 2.3e-33 115.8 0.0 5e-33 114.7 0.0 1.5 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) ADH_N PF08240.12 CRK33785.1 - 3.9e-27 94.3 2.3 9.1e-27 93.1 2.3 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.6 CRK33785.1 - 1.8e-06 27.8 1.6 3.6e-06 26.8 1.6 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N PF00107.26 CRK33785.1 - 1.9e-06 27.8 1.2 0.00038 20.4 0.2 3.2 2 1 0 2 2 2 1 Zinc-binding dehydrogenase Sugar_tr PF00083.24 CRK33787.1 - 4.6e-52 177.4 23.6 1.2e-49 169.4 23.6 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK33787.1 - 2.5e-09 36.5 45.6 2.1e-07 30.2 33.5 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily GCR1_C PF12550.8 CRK33789.1 - 9.7e-19 67.5 1.3 2e-18 66.4 1.3 1.6 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes DUF1515 PF07439.11 CRK33789.1 - 0.37 10.8 3.2 0.41 10.7 1.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) KfrA_N PF11740.8 CRK33789.1 - 3.5 8.3 9.8 2.9 8.6 4.1 3.1 3 0 0 3 3 3 0 Plasmid replication region DNA-binding N-term Wbp11 PF09429.10 CRK33789.1 - 4.3 7.8 6.0 1.7 9.1 2.6 2.0 2 0 0 2 2 2 0 WW domain binding protein 11 Glyco_hydro_92 PF07971.12 CRK33794.1 - 1e-86 291.7 0.0 1.5e-78 264.8 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 CRK33794.1 - 3.8e-59 200.5 0.0 5.6e-59 199.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain ETF_QO PF05187.13 CRK33796.1 - 3.8e-29 100.9 5.9 2e-19 69.6 2.6 2.4 1 1 1 2 2 2 2 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S DAO PF01266.24 CRK33796.1 - 2.4e-08 34.0 0.4 9.1e-05 22.2 0.3 2.4 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CRK33796.1 - 6.5e-08 32.7 0.0 3e-07 30.6 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CRK33796.1 - 4.1e-05 23.0 0.0 0.00013 21.3 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CRK33796.1 - 6.9e-05 22.1 0.3 0.0035 16.5 0.6 2.2 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 CRK33796.1 - 0.00011 21.1 0.4 0.00015 20.6 0.4 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 CRK33796.1 - 0.00012 21.4 0.0 0.0067 15.7 0.1 2.2 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 CRK33796.1 - 0.00023 21.6 0.2 0.46 11.1 0.0 2.7 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CRK33796.1 - 0.0014 18.0 0.1 0.0024 17.2 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 CRK33796.1 - 0.0018 17.7 0.0 0.0031 16.9 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 CRK33796.1 - 0.0025 17.8 0.1 0.0069 16.4 0.1 1.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding Trp_halogenase PF04820.14 CRK33796.1 - 0.0038 16.1 0.0 0.2 10.4 0.1 2.2 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_3 PF13738.6 CRK33796.1 - 0.0051 16.1 0.4 0.0073 15.6 0.4 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 CRK33796.1 - 0.034 13.4 0.0 0.063 12.6 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 CRK33796.1 - 0.039 13.0 0.2 0.055 12.5 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.22 CRK33796.1 - 0.086 11.9 0.1 0.12 11.4 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Fer4_2 PF12797.7 CRK33796.1 - 0.13 12.4 0.6 0.32 11.2 0.6 1.6 1 0 0 1 1 1 0 4Fe-4S binding domain TBP PF00352.21 CRK33798.1 - 1.3e-67 223.7 0.1 6.8e-33 112.5 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 CRK33798.1 - 0.00011 22.3 0.0 0.21 11.7 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 CRK33798.1 - 0.12 12.2 0.1 0.66 9.8 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) DAO PF01266.24 CRK33800.1 - 5.1e-45 154.6 11.7 8.5e-28 97.9 5.5 2.7 1 1 2 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 CRK33800.1 - 1.5e-05 25.0 6.9 0.02 14.9 0.4 3.3 4 1 0 4 4 4 2 FAD-NAD(P)-binding Biotin_lipoyl_2 PF13533.6 CRK33800.1 - 3.5e-05 23.5 0.0 0.37 10.7 0.0 2.5 2 0 0 2 2 2 2 Biotin-lipoyl like NAD_binding_8 PF13450.6 CRK33800.1 - 9.9e-05 22.5 0.0 0.0055 16.9 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CRK33800.1 - 0.0014 18.0 0.1 0.27 10.4 0.0 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CRK33800.1 - 0.022 13.8 0.1 0.1 11.6 0.0 2.0 3 0 0 3 3 3 0 Glucose inhibited division protein A Sacchrp_dh_NADP PF03435.18 CRK33800.1 - 0.13 12.6 0.0 0.38 11.0 0.0 1.8 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Sm_multidrug_ex PF06695.11 CRK33800.1 - 0.29 11.8 3.9 13 6.4 0.4 2.5 2 0 0 2 2 2 0 Putative small multi-drug export protein CBM_10 PF02013.16 CRK33800.1 - 0.52 10.8 3.6 20 5.7 0.3 2.5 2 0 0 2 2 2 0 Cellulose or protein binding domain Methyltransf_16 PF10294.9 CRK33803.1 - 1.6e-13 50.8 0.0 2.8e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase Fungal_trans PF04082.18 CRK33803.1 - 2.4e-09 36.6 0.3 7.7e-09 35.0 0.3 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain PrmA PF06325.13 CRK33803.1 - 0.0027 17.1 0.0 0.0043 16.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.15 CRK33803.1 - 0.19 11.3 0.0 1.1 8.8 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical protein 95 DUF2461 PF09365.10 CRK33805.1 - 1.6e-32 113.1 0.1 1.6e-32 113.1 0.1 1.9 2 0 0 2 2 2 1 Conserved hypothetical protein (DUF2461) eIF3_subunit PF08597.10 CRK33805.1 - 0.084 12.8 27.1 0.18 11.7 27.1 1.5 1 1 0 1 1 1 0 Translation initiation factor eIF3 subunit FCP1_C PF09309.10 CRK33805.1 - 1.7 8.5 21.0 2.5 7.9 21.0 1.2 1 0 0 1 1 1 0 FCP1, C-terminal Nop14 PF04147.12 CRK33805.1 - 7.1 4.7 24.5 9.3 4.3 24.5 1.1 1 0 0 1 1 1 0 Nop14-like family Ribosomal_TL5_C PF14693.6 CRK33806.1 - 0.0039 17.5 0.1 5.6 7.4 0.0 2.7 2 0 0 2 2 2 2 Ribosomal protein TL5, C-terminal domain DUF3786 PF12654.7 CRK33806.1 - 0.021 14.4 0.0 17 5.0 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF3786) PSCyt3 PF07627.11 CRK33806.1 - 0.04 14.2 0.0 14 6.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1588) His_Phos_1 PF00300.22 CRK33807.1 - 4.3e-19 69.0 0.1 8.9e-19 67.9 0.1 1.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Exo_endo_phos PF03372.23 CRK33809.1 - 0.064 12.8 0.0 0.085 12.4 0.0 1.3 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family His_Phos_1 PF00300.22 CRK33810.1 - 1.9e-18 66.9 0.2 4.2e-18 65.8 0.2 1.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Dioxygenase_C PF00775.21 CRK33811.1 - 4.4e-36 124.0 0.0 6.4e-36 123.5 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 CRK33811.1 - 3e-25 87.8 0.5 7.3e-25 86.6 0.1 1.9 2 0 0 2 2 2 1 Catechol dioxygenase N terminus ArsB PF02040.15 CRK33811.1 - 1.2e-07 31.5 9.9 4.9e-07 29.4 6.9 2.1 2 0 0 2 2 2 1 Arsenical pump membrane protein SpaA PF17802.1 CRK33811.1 - 0.024 15.0 0.0 0.057 13.8 0.0 1.6 1 0 0 1 1 1 0 Prealbumin-like fold domain DUF4597 PF15366.6 CRK33813.1 - 4.6 7.1 5.4 76 3.2 5.4 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4597) 2-Hacid_dh_C PF02826.19 CRK33814.1 - 2.3e-52 176.9 0.3 5.8e-52 175.6 0.1 1.8 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CRK33814.1 - 1.7e-36 124.8 1.0 3.8e-36 123.7 0.5 1.9 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain DUF21 PF01595.20 CRK33814.1 - 5.9e-33 114.0 0.0 1.1e-32 113.2 0.0 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 CRK33814.1 - 0.00059 20.2 0.7 0.039 14.4 0.0 3.6 4 0 0 4 4 4 1 CBS domain ACT PF01842.25 CRK33814.1 - 0.0024 17.6 0.0 0.01 15.6 0.0 2.1 1 0 0 1 1 1 1 ACT domain AlaDh_PNT_C PF01262.21 CRK33814.1 - 0.025 13.9 1.8 0.059 12.7 0.1 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain XdhC_C PF13478.6 CRK33814.1 - 0.074 13.6 0.2 0.23 11.9 0.0 2.0 2 0 0 2 2 2 0 XdhC Rossmann domain Big_1 PF02369.16 CRK33815.1 - 0.062 13.3 0.3 0.094 12.7 0.3 1.3 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 1) Fungal_trans PF04082.18 CRK33817.1 - 4.5e-30 104.6 0.0 6.3e-30 104.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK33817.1 - 2e-07 31.0 7.7 4.6e-07 29.8 7.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 CRK33818.1 - 5.4e-12 45.3 5.9 1.2e-11 44.1 5.9 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily PhnI PF05861.12 CRK33818.1 - 0.13 11.1 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 Bacterial phosphonate metabolism protein (PhnI) Cytochrom_B_C PF00032.17 CRK33819.1 - 0.027 14.8 2.5 0.043 14.1 0.1 2.4 1 1 1 2 2 2 0 Cytochrome b(C-terminal)/b6/petD DUF423 PF04241.15 CRK33819.1 - 0.038 14.2 0.6 0.11 12.8 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF423) DUF4231 PF14015.6 CRK33819.1 - 4.1 7.9 6.6 1.7 9.2 2.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DUF1741 PF08427.10 CRK33821.1 - 3e-83 279.0 0.0 5e-83 278.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) Fe-S_biosyn PF01521.20 CRK33822.1 - 2.5e-11 43.7 0.0 3.4e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Ndc1_Nup PF09531.10 CRK33822.1 - 0.85 8.2 5.7 0.98 8.0 5.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup AMP-binding PF00501.28 CRK33823.1 - 6.7e-22 77.7 0.0 7.9e-22 77.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CRK33823.1 - 9.7e-05 23.3 0.1 0.00015 22.7 0.1 1.3 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Acyl_transf_1 PF00698.21 CRK33824.1 - 8.4e-19 68.2 0.2 8.7e-19 68.2 0.2 1.0 1 0 0 1 1 1 1 Acyl transferase domain DUF915 PF06028.11 CRK33824.1 - 0.25 10.6 0.0 0.32 10.3 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) GATase PF00117.28 CRK33826.1 - 5.1e-22 78.6 0.0 5.9e-22 78.4 0.0 1.0 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 CRK33826.1 - 4e-08 33.3 0.0 3.2e-06 27.1 0.0 2.0 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 CRK33826.1 - 5.1e-08 32.8 0.1 1.6e-07 31.2 0.1 1.7 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 CRK33826.1 - 0.0033 17.2 0.2 0.093 12.5 0.0 2.1 2 0 0 2 2 2 1 Peptidase C26 Sdh5 PF03937.16 CRK33827.1 - 1.3e-24 85.9 0.1 4.2e-24 84.3 0.2 1.8 2 0 0 2 2 2 1 Flavinator of succinate dehydrogenase Peptidase_M20 PF01546.28 CRK33827.1 - 6e-24 84.9 0.0 6.4e-24 84.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Proteasome PF00227.26 CRK33828.1 - 1.8e-24 86.3 0.0 2e-24 86.1 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit FA_desaturase PF00487.24 CRK33829.1 - 2.9e-07 30.6 0.0 3.4e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Fatty acid desaturase GCV_H PF01597.19 CRK33832.1 - 1.5e-29 102.3 0.8 1.7e-29 102.2 0.8 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 CRK33832.1 - 0.001 18.8 0.4 0.0014 18.4 0.4 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme RnfC_N PF13375.6 CRK33832.1 - 0.011 15.7 0.1 0.011 15.7 0.1 1.2 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain Biotin_lipoyl_2 PF13533.6 CRK33832.1 - 0.041 13.7 0.3 5.8 6.8 0.0 2.2 1 1 1 2 2 2 0 Biotin-lipoyl like DUF2118 PF09891.9 CRK33832.1 - 0.042 13.8 0.0 0.055 13.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) DUF2686 PF10887.8 CRK33832.1 - 0.056 12.4 0.0 0.069 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2686) Mito_carr PF00153.27 CRK33834.1 - 1.8e-20 72.7 0.0 1.5e-11 44.0 0.0 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein MPP6 PF10175.9 CRK33835.1 - 1.9e-10 41.4 7.7 1.9e-05 25.2 3.4 2.4 2 1 0 2 2 2 2 M-phase phosphoprotein 6 zf-CCHC PF00098.23 CRK33835.1 - 8.6e-05 22.4 2.9 0.00013 21.9 2.9 1.3 1 0 0 1 1 1 1 Zinc knuckle CDC45 PF02724.14 CRK33835.1 - 0.84 7.8 11.7 0.062 11.6 7.3 1.3 2 0 0 2 2 2 0 CDC45-like protein zf-CHCC PF10276.9 CRK33836.1 - 1.3e-16 60.3 0.8 1.9e-16 59.8 0.8 1.2 1 0 0 1 1 1 1 Zinc-finger domain COX5B PF01215.19 CRK33836.1 - 0.2 11.4 1.4 1.8 8.3 1.4 2.0 1 1 0 1 1 1 0 Cytochrome c oxidase subunit Vb NUDIX_2 PF13869.6 CRK33837.1 - 5.4e-52 176.1 0.0 6.1e-52 175.9 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase IHO1 PF15771.5 CRK33838.1 - 0.018 13.9 2.5 0.018 13.9 2.5 1.0 1 0 0 1 1 1 0 Interactor of HORMAD1 protein 1 Atrophin-1 PF03154.15 CRK33838.1 - 0.21 9.8 13.6 0.25 9.6 13.6 1.0 1 0 0 1 1 1 0 Atrophin-1 family U79_P34 PF03064.16 CRK33838.1 - 1.2 8.4 11.9 1.4 8.2 11.9 1.0 1 0 0 1 1 1 0 HSV U79 / HCMV P34 CDC45 PF02724.14 CRK33838.1 - 2.8 6.1 10.7 2.9 6.1 10.7 1.0 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.7 CRK33838.1 - 3.3 5.7 3.4 3.5 5.6 3.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Presenilin PF01080.17 CRK33838.1 - 5.9 5.5 6.4 6.4 5.4 6.4 1.0 1 0 0 1 1 1 0 Presenilin Med19 PF10278.9 CRK33838.1 - 8.4 6.3 11.2 11 5.9 11.2 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Lung_7-TM_R PF06814.13 CRK33840.1 - 1.6e-15 57.1 0.1 1.9e-15 56.9 0.1 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor Egh16-like PF11327.8 CRK33841.1 - 4.2e-20 72.9 1.0 5e-20 72.7 1.0 1.2 1 0 0 1 1 1 1 Egh16-like virulence factor Coatomer_b_Cpla PF14806.6 CRK33843.1 - 3.2e-41 140.3 0.4 4.2e-41 139.9 0.4 1.2 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.12 CRK33843.1 - 1.1e-15 57.8 0.2 2.3e-15 56.8 0.0 1.6 2 0 0 2 2 2 1 Coatomer beta C-terminal region AP4E_app_platf PF14807.6 CRK33843.1 - 0.0013 19.0 0.2 0.0023 18.3 0.2 1.4 1 0 0 1 1 1 1 Adaptin AP4 complex epsilon appendage platform B2-adapt-app_C PF09066.10 CRK33843.1 - 0.024 14.7 0.3 0.067 13.3 0.3 1.7 2 0 0 2 2 2 0 Beta2-adaptin appendage, C-terminal sub-domain Myosin_head PF00063.21 CRK33845.1 - 1.5e-49 168.8 0.2 2e-49 168.5 0.2 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Aldose_epim PF01263.20 CRK33845.1 - 9e-25 87.6 0.0 1.4e-24 87.0 0.0 1.2 1 0 0 1 1 1 1 Aldose 1-epimerase Glyco_hydro_36N PF16875.5 CRK33845.1 - 0.016 14.7 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 36 N-terminal domain AAA_22 PF13401.6 CRK33845.1 - 0.018 15.3 0.0 0.035 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CRK33845.1 - 0.021 15.2 0.0 0.037 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Mg_chelatase PF01078.21 CRK33845.1 - 0.034 13.5 0.0 0.052 12.9 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 CRK33845.1 - 0.045 13.7 0.0 0.081 12.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.26 CRK33845.1 - 0.048 13.4 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.27 CRK33845.1 - 0.092 13.3 0.1 0.16 12.5 0.1 1.4 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.12 CRK33845.1 - 0.11 11.8 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.22 CRK33845.1 - 0.14 12.5 0.0 0.3 11.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase TrwB_AAD_bind PF10412.9 CRK33845.1 - 0.15 10.9 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain T2SSE PF00437.20 CRK33845.1 - 0.19 10.7 0.1 4.1 6.4 0.0 2.0 1 1 0 2 2 2 0 Type II/IV secretion system protein Glyco_hydro_31 PF01055.26 CRK33847.1 - 1.2e-23 84.0 3.2 1.3e-23 83.9 3.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 GTP_EFTU PF00009.27 CRK33850.1 - 0.021 14.3 0.0 0.026 14.0 0.0 1.1 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Dynamitin PF04912.14 CRK33852.1 - 7.1e-26 91.4 6.6 7.6e-26 91.3 6.6 1.0 1 0 0 1 1 1 1 Dynamitin Corazonin PF17308.2 CRK33852.1 - 0.00058 20.2 0.1 0.00081 19.8 0.1 1.2 1 0 0 1 1 1 1 Pro-corazonin Spore_III_AB PF09548.10 CRK33852.1 - 0.0047 17.1 0.2 0.007 16.5 0.2 1.3 1 0 0 1 1 1 1 Stage III sporulation protein AB (spore_III_AB) Phage_GP20 PF06810.11 CRK33852.1 - 0.019 14.8 2.2 0.025 14.4 2.2 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 Peptidase_M75 PF09375.10 CRK33852.1 - 0.026 14.0 1.8 0.033 13.6 1.8 1.1 1 0 0 1 1 1 0 Imelysin ATF7IP_BD PF16788.5 CRK33852.1 - 0.029 14.5 0.3 0.045 13.8 0.3 1.2 1 0 0 1 1 1 0 ATF-interacting protein binding domain AAA_13 PF13166.6 CRK33852.1 - 0.081 11.6 2.8 0.091 11.4 2.8 1.0 1 0 0 1 1 1 0 AAA domain DUF4407 PF14362.6 CRK33852.1 - 0.15 11.4 3.9 0.18 11.1 3.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1192 PF06698.11 CRK33852.1 - 0.28 11.3 7.3 0.14 12.3 4.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) SPRY PF00622.28 CRK33854.1 - 0.00051 20.1 0.0 0.013 15.6 0.0 2.7 3 0 0 3 3 3 1 SPRY domain EIF_2_alpha PF07541.12 CRK33855.1 - 3.9e-37 126.9 0.0 7.1e-37 126.1 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 CRK33855.1 - 1.3e-13 51.1 0.9 2.6e-13 50.1 0.9 1.6 1 0 0 1 1 1 1 S1 RNA binding domain Mito_carr PF00153.27 CRK33855.1 - 1.4e-08 34.6 0.1 1.2e-07 31.5 0.0 2.2 2 0 0 2 2 2 1 Mitochondrial carrier protein Peptidase_S24 PF00717.23 CRK33855.1 - 4.3e-05 23.4 0.1 0.00036 20.4 0.0 2.4 2 0 0 2 2 2 1 Peptidase S24-like Peptidase_S26 PF10502.9 CRK33855.1 - 0.13 12.1 0.0 2.9 7.7 0.0 2.6 1 1 1 2 2 2 0 Signal peptidase, peptidase S26 WD40 PF00400.32 CRK33857.1 - 1.7e-06 28.6 0.0 0.0079 17.0 0.0 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat Bromodomain PF00439.25 CRK33863.1 - 8.4e-25 86.7 0.6 1.1e-24 86.3 0.6 1.1 1 0 0 1 1 1 1 Bromodomain NUDE_C PF04880.13 CRK33867.1 - 0.093 13.2 5.3 0.12 12.9 5.3 1.2 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Gti1_Pac2 PF09729.9 CRK33867.1 - 2.9 7.9 7.6 3.4 7.7 7.6 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family HGTP_anticodon PF03129.20 CRK33871.1 - 1.8e-08 34.4 0.0 2.3e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Anticodon binding domain Apelin PF15360.6 CRK33871.1 - 0.019 15.5 0.1 0.031 14.8 0.1 1.3 1 0 0 1 1 1 0 APJ endogenous ligand HBS1_N PF08938.10 CRK33871.1 - 0.16 12.3 0.0 0.2 12.0 0.0 1.2 1 0 0 1 1 1 0 HBS1 N-terminus Sin3a_C PF16879.5 CRK33877.1 - 1.9e-17 63.9 0.0 2.3e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 C-terminal domain of Sin3a protein GTP_EFTU PF00009.27 CRK33877.1 - 2.8e-05 23.7 0.1 3.9e-05 23.3 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain G-alpha PF00503.20 CRK33877.1 - 0.56 9.3 3.2 1.5 7.9 3.2 1.8 1 1 0 1 1 1 0 G-protein alpha subunit FAD_binding_2 PF00890.24 CRK33878.1 - 3e-32 112.2 0.0 5.6e-32 111.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 CRK33878.1 - 2e-21 75.9 0.0 1.5e-20 73.1 0.0 2.2 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain BRK PF07533.16 CRK33878.1 - 0.1 12.3 0.4 0.41 10.3 0.0 2.1 2 0 0 2 2 2 0 BRK domain ADK PF00406.22 CRK33880.1 - 4.5e-30 104.7 0.1 5.5e-30 104.5 0.1 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CRK33880.1 - 1.6e-23 83.6 0.0 1.9e-23 83.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CRK33880.1 - 0.0014 19.1 0.0 0.0019 18.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CRK33880.1 - 0.0039 17.4 0.0 0.0043 17.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 CRK33880.1 - 0.16 11.6 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Thymidylate kinase Ploopntkinase3 PF18751.1 CRK33880.1 - 0.17 11.8 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Zeta_toxin PF06414.12 CRK33880.1 - 0.17 11.1 0.1 0.19 11.0 0.1 1.3 1 1 0 1 1 1 0 Zeta toxin Chitin_synth_2 PF03142.15 CRK33882.1 - 1.1e-07 30.8 0.1 1.3e-07 30.6 0.1 1.0 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 CRK33882.1 - 5.5e-05 23.2 0.8 6.4e-05 23.0 0.8 1.0 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Peptidase_M43 PF05572.13 CRK33883.1 - 5.6e-12 45.8 0.8 8.5e-12 45.2 0.8 1.3 1 1 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 CRK33883.1 - 4.6e-05 23.7 0.2 5.1e-05 23.5 0.2 1.1 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M10 PF00413.24 CRK33883.1 - 0.00015 21.6 0.0 0.00033 20.5 0.0 1.3 1 1 0 1 1 1 1 Matrixin Reprolysin_3 PF13582.6 CRK33883.1 - 0.00023 21.7 0.1 0.00035 21.1 0.1 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 CRK33883.1 - 0.0062 16.2 0.8 0.0064 16.2 0.8 1.2 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 CRK33883.1 - 0.014 14.7 0.2 0.02 14.1 0.2 1.2 1 0 0 1 1 1 0 Met-zincin Thioredoxin PF00085.20 CRK33886.1 - 3.1e-27 94.6 0.2 2.2e-25 88.6 0.0 2.7 2 1 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 CRK33886.1 - 1.2e-06 29.0 0.2 5.7e-05 23.5 0.1 2.8 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CRK33886.1 - 8.1e-06 26.1 0.0 0.0058 16.9 0.0 3.1 2 1 1 3 3 3 1 Thioredoxin-like Thioredoxin_7 PF13899.6 CRK33886.1 - 0.0011 19.1 0.2 0.011 15.8 0.1 2.2 2 0 0 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.21 CRK33886.1 - 0.004 17.1 0.4 0.044 13.7 0.1 2.2 1 1 1 2 2 2 1 AhpC/TSA family Thioredoxin_5 PF13743.6 CRK33886.1 - 0.01 15.5 0.0 4.5 6.9 0.0 2.8 2 1 1 3 3 3 0 Thioredoxin TraF PF13728.6 CRK33886.1 - 0.011 15.6 0.0 0.092 12.6 0.0 2.2 2 0 0 2 2 2 0 F plasmid transfer operon protein Thioredoxin_3 PF13192.6 CRK33886.1 - 0.011 15.8 0.0 0.27 11.3 0.0 2.3 2 1 0 2 2 2 0 Thioredoxin domain HyaE PF07449.11 CRK33886.1 - 0.081 12.9 0.0 2.6 8.1 0.0 2.4 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Calsequestrin PF01216.17 CRK33886.1 - 0.1 11.6 0.1 0.13 11.3 0.1 1.1 1 0 0 1 1 1 0 Calsequestrin Arrestin_N PF00339.29 CRK33887.1 - 4.2e-05 23.6 0.0 5e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain SNase PF00565.17 CRK33888.1 - 0.0037 17.7 0.0 0.0053 17.2 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Ribosomal_L16 PF00252.18 CRK33889.1 - 3.5e-35 120.9 0.0 3.8e-35 120.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e DUF4502 PF14950.6 CRK33890.1 - 0.06 12.8 1.5 0.085 12.3 1.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4502) Aldedh PF00171.22 CRK33891.1 - 2.4e-40 138.4 0.1 2.7e-40 138.3 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 CRK33891.1 - 0.076 12.0 0.0 0.083 11.9 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Tubulin_C PF03953.17 CRK33892.1 - 3.9e-16 59.4 0.1 5.4e-16 58.9 0.1 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain AAA PF00004.29 CRK33894.1 - 3.1e-21 76.2 0.0 9.4e-21 74.6 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SIS PF01380.22 CRK33894.1 - 2.9e-16 59.5 0.0 4.8e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 SIS domain Flavodoxin_2 PF02525.17 CRK33895.1 - 0.019 14.7 0.1 0.023 14.4 0.1 1.2 1 0 0 1 1 1 0 Flavodoxin-like fold DUF1543 PF07566.12 CRK33895.1 - 0.091 12.5 0.2 0.17 11.7 0.2 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1543) DUF4495 PF14906.6 CRK33895.1 - 0.16 11.0 0.4 0.33 10.0 0.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4495) Pkinase PF00069.25 CRK33897.1 - 1.7e-13 50.5 0.0 1.7e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK33897.1 - 4e-05 23.0 0.0 4.3e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Vps16_C PF04840.12 CRK33899.1 - 1.8e-06 27.2 0.0 2.4e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Vps16, C-terminal region TPT PF03151.16 CRK33900.1 - 4.5e-12 45.9 10.5 5.1e-12 45.7 10.5 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family DUF2427 PF10348.9 CRK33904.1 - 3.6e-06 26.7 7.4 4e-06 26.6 7.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2427) Cytochrom_B561 PF03188.16 CRK33904.1 - 0.00067 19.8 7.1 0.0007 19.7 7.1 1.1 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF4079 PF13301.6 CRK33904.1 - 0.025 14.7 5.2 0.03 14.5 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4079) MFS_1 PF07690.16 CRK33904.1 - 0.81 8.5 11.5 0.33 9.8 8.8 1.6 1 1 0 1 1 1 0 Major Facilitator Superfamily DUF3716 PF12511.8 CRK33905.1 - 3.5e-05 23.8 0.1 5e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Alg6_Alg8 PF03155.15 CRK33906.1 - 2.5e-15 56.4 10.4 2.5e-15 56.4 10.4 1.4 2 0 0 2 2 2 1 ALG6, ALG8 glycosyltransferase family HEAT PF02985.22 CRK33906.1 - 9e-05 22.4 2.6 0.015 15.5 0.1 3.7 4 0 0 4 4 4 1 HEAT repeat Cnd1 PF12717.7 CRK33906.1 - 0.0018 18.3 0.0 0.29 11.1 0.0 2.2 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CRK33906.1 - 0.0043 17.4 0.1 0.25 11.7 0.0 2.2 2 0 0 2 2 2 1 HEAT repeats MTP18 PF10558.9 CRK33906.1 - 0.064 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial 18 KDa protein (MTP18) Vac14_Fab1_bd PF12755.7 CRK33906.1 - 0.13 12.9 0.2 3.5 8.3 0.0 2.8 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region NAD_binding_4 PF07993.12 CRK33908.1 - 2.9e-07 29.9 0.0 4.1e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein KR PF08659.10 CRK33908.1 - 0.0026 17.7 0.0 0.0033 17.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CRK33908.1 - 0.012 15.1 0.0 0.014 14.9 0.0 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 CRK33908.1 - 0.078 13.4 0.0 0.1 13.0 0.0 1.2 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain MoCF_biosynth PF00994.24 CRK33908.1 - 0.13 11.9 0.0 6.1 6.5 0.0 2.1 1 1 1 2 2 2 0 Probable molybdopterin binding domain FKBP_C PF00254.28 CRK33909.1 - 0.0012 19.1 0.0 0.0015 18.8 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DnaJ_CXXCXGXG PF00684.19 CRK33910.1 - 9.2e-10 38.7 10.4 1.5e-09 38.1 10.4 1.3 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 CRK33910.1 - 0.33 11.0 8.2 0.24 11.4 2.9 2.2 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 CRK33910.1 - 1.2 9.2 7.2 0.26 11.3 1.9 2.0 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF5351 PF17302.2 CRK33910.1 - 2.6 8.3 13.3 0.82 9.9 0.5 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5351) Lar_restr_allev PF14354.6 CRK33910.1 - 2.8 8.4 7.4 0.89 10.0 2.0 2.1 1 1 1 2 2 2 0 Restriction alleviation protein Lar RNA_pol_L PF01193.24 CRK33911.1 - 3.5e-08 32.8 0.0 4.6e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Hexokinase_2 PF03727.16 CRK33913.1 - 1.2e-64 218.0 0.0 2.1e-62 210.7 0.0 2.1 1 1 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 CRK33913.1 - 1.2e-16 61.2 0.0 4e-16 59.5 0.0 1.8 1 1 1 2 2 2 1 Hexokinase Zn_clus PF00172.18 CRK33914.1 - 5.6e-07 29.6 9.0 9.2e-07 28.9 9.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glucosamine_iso PF01182.20 CRK33915.1 - 3.6e-22 79.4 0.0 5.3e-22 78.8 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase FAD_binding_8 PF08022.12 CRK33915.1 - 0.028 14.5 0.0 0.06 13.4 0.0 1.5 1 0 0 1 1 1 0 FAD-binding domain Sugar-bind PF04198.13 CRK33915.1 - 0.066 12.3 0.1 0.11 11.6 0.1 1.3 1 0 0 1 1 1 0 Putative sugar-binding domain FabA PF07977.13 CRK33915.1 - 0.16 11.6 0.0 0.34 10.5 0.0 1.6 1 1 0 1 1 1 0 FabA-like domain DUF908 PF06012.12 CRK33916.1 - 0.053 12.9 0.1 0.074 12.5 0.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Sugarporin_N PF11471.8 CRK33916.1 - 0.39 10.7 1.8 6.8 6.7 0.0 2.4 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension AAA_12 PF13087.6 CRK33917.1 - 1.4e-15 57.5 0.0 2.6e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CRK33917.1 - 1.2e-11 44.9 0.0 7.8e-06 25.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 CRK33917.1 - 1.6e-05 24.7 0.7 0.0032 17.2 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 CRK33917.1 - 9.2e-05 22.8 0.0 0.00036 20.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 CRK33917.1 - 0.0016 18.3 0.1 0.0047 16.8 0.0 1.8 2 0 0 2 2 2 1 Helicase Bunya_G2 PF03563.13 CRK33917.1 - 0.0078 15.5 0.0 0.02 14.2 0.0 1.6 1 0 0 1 1 1 1 Bunyavirus glycoprotein G2 Pectate_lyase PF03211.13 CRK33918.1 - 5e-87 290.7 8.2 6.1e-87 290.4 8.2 1.1 1 0 0 1 1 1 1 Pectate lyase MFS_1 PF07690.16 CRK33919.1 - 5.4e-31 107.8 71.3 5.6e-20 71.6 41.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sec23_BS PF08033.12 CRK33919.1 - 0.0066 17.2 0.1 0.035 14.8 0.0 2.2 3 0 0 3 3 3 1 Sec23/Sec24 beta-sandwich domain Hemerythrin PF01814.23 CRK33920.1 - 1.1e-08 35.8 4.4 1.5e-08 35.3 4.4 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Ctr PF04145.15 CRK33921.1 - 4.9e-40 137.5 0.3 6.2e-40 137.2 0.3 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Cadherin_tail PF15974.5 CRK33921.1 - 0.18 12.1 0.1 0.38 11.1 0.1 1.4 1 0 0 1 1 1 0 Cadherin C-terminal cytoplasmic tail, catenin-binding region YfhO PF09586.10 CRK33921.1 - 2 6.6 7.0 2.9 6.0 7.0 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO WD40 PF00400.32 CRK33922.1 - 4.5e-10 40.0 3.9 1.3e-05 25.9 0.4 5.0 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK33922.1 - 0.0035 17.6 0.1 2.6 8.4 0.1 3.6 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain zinc_ribbon_16 PF17034.5 CRK33922.1 - 0.097 12.9 0.9 0.26 11.5 0.9 1.7 1 0 0 1 1 1 0 Zinc-ribbon like family Ribosomal_L37ae PF01780.19 CRK33922.1 - 0.1 12.7 1.2 0.36 10.9 1.2 1.8 1 0 0 1 1 1 0 Ribosomal L37ae protein family eIF2A PF08662.11 CRK33922.1 - 0.21 11.4 0.0 0.7 9.7 0.0 1.7 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A PHD PF00628.29 CRK33922.1 - 5 7.1 8.5 18 5.3 0.4 3.3 2 1 1 3 3 3 0 PHD-finger VPS38 PF17649.1 CRK33923.1 - 5.3e-12 45.4 1.0 1.9e-07 30.3 0.1 3.5 3 1 1 4 4 4 3 Vacuolar protein sorting 38 Atg14 PF10186.9 CRK33923.1 - 6e-11 42.0 10.4 6.4e-10 38.6 10.4 2.0 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 HAP1_N PF04849.13 CRK33923.1 - 0.41 9.8 8.2 0.67 9.1 8.2 1.3 1 0 0 1 1 1 0 HAP1 N-terminal conserved region AAA_13 PF13166.6 CRK33923.1 - 1.4 7.5 7.1 3.7 6.1 6.1 1.9 2 0 0 2 2 2 0 AAA domain TPR_MLP1_2 PF07926.12 CRK33923.1 - 8.6 6.4 14.8 32 4.6 14.8 1.9 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein TNFR_c6 PF00020.18 CRK33924.1 - 4.2 7.8 13.9 5.5 7.5 2.6 2.8 1 1 1 2 2 2 0 TNFR/NGFR cysteine-rich region Ank_5 PF13857.6 CRK33927.1 - 9.2e-05 22.7 0.2 0.0025 18.1 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 CRK33927.1 - 0.00086 19.8 0.0 0.02 15.5 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) PAN_3 PF08277.12 CRK33928.1 - 0.01 15.6 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 PAN-like domain PAN_1 PF00024.26 CRK33928.1 - 0.018 15.0 0.4 0.036 14.0 0.4 1.4 1 0 0 1 1 1 0 PAN domain PAN_4 PF14295.6 CRK33928.1 - 0.02 14.8 1.7 0.072 13.0 0.9 2.1 2 0 0 2 2 2 0 PAN domain CFEM PF05730.11 CRK33929.1 - 8.7e-08 32.2 9.8 1.6e-07 31.3 9.8 1.4 1 0 0 1 1 1 1 CFEM domain Fungal_trans_2 PF11951.8 CRK33930.1 - 1.1e-06 27.7 0.8 1.7e-06 27.1 0.8 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain PNRC PF15365.6 CRK33930.1 - 0.00087 19.0 0.5 0.0021 17.8 0.5 1.7 1 0 0 1 1 1 1 Proline-rich nuclear receptor coactivator motif CPSF_A PF03178.15 CRK33931.1 - 2.1e-84 283.6 0.0 4.9e-84 282.4 0.0 1.7 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.9 CRK33931.1 - 2.7e-16 59.3 0.0 9.2e-16 57.5 0.0 1.9 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term LMBR1 PF04791.16 CRK33932.1 - 6.7e-10 38.5 0.2 6.7e-10 38.5 0.2 3.1 2 1 0 3 3 3 2 LMBR1-like membrane protein MPC PF03650.13 CRK33932.1 - 0.03 14.5 0.8 0.081 13.1 0.8 1.8 1 0 0 1 1 1 0 Mitochondrial pyruvate carriers TMEM208_SND2 PF05620.11 CRK33932.1 - 3.9 7.2 0.0 3.9 7.2 0.0 4.5 6 1 0 6 6 6 0 SRP-independent targeting protein 2/TMEM208 Pup PF05639.11 CRK33934.1 - 3.9 8.4 9.9 1.4 9.9 0.2 2.7 2 0 0 2 2 2 0 Pup-like protein GRP PF07172.11 CRK33936.1 - 3.1e-06 27.8 16.6 6.1e-06 26.8 16.6 1.5 1 0 0 1 1 1 1 Glycine rich protein family PIG-U PF06728.13 CRK33938.1 - 2.7e-118 395.4 16.1 3e-118 395.2 16.1 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U 8TM_micro PF17028.5 CRK33938.1 - 3.4 7.3 6.2 15 5.2 6.2 2.0 1 1 0 1 1 1 0 8TM Microsporidial transmembrane domain Tom37 PF10568.9 CRK33942.1 - 1.1e-31 109.8 3.1 1.6e-31 109.2 3.1 1.3 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 CRK33942.1 - 0.00043 20.0 0.2 0.0014 18.3 0.1 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 CRK33942.1 - 0.0023 18.6 0.0 0.0046 17.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain PIG-U PF06728.13 CRK33944.1 - 7.5e-41 140.4 0.0 9e-41 140.2 0.0 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Methyltransf_25 PF13649.6 CRK33946.1 - 8.7e-13 48.8 0.0 1.5e-12 48.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CRK33946.1 - 7.4e-11 42.6 0.0 1.3e-10 41.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK33946.1 - 3.6e-07 30.8 0.0 5.4e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK33946.1 - 0.00013 21.8 0.0 0.00014 21.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CRK33946.1 - 0.01 15.7 0.0 0.019 14.8 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 CRK33946.1 - 0.043 13.1 0.0 0.053 12.8 0.0 1.1 1 0 0 1 1 1 0 O-methyltransferase domain Ubie_methyltran PF01209.18 CRK33946.1 - 0.17 11.2 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 CRK33947.1 - 3.8e-18 66.0 0.0 7.5e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CRK33947.1 - 3.7e-14 53.1 0.0 6.4e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK33947.1 - 3e-11 43.9 0.0 5.1e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CRK33947.1 - 8.7e-10 38.7 0.0 1.7e-09 37.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK33947.1 - 1.3e-09 38.0 0.0 1.9e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CRK33947.1 - 1.1e-05 25.0 0.0 1.8e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 CRK33947.1 - 0.0002 20.8 0.0 0.00027 20.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain CMAS PF02353.20 CRK33947.1 - 0.00078 18.8 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 CRK33947.1 - 0.0068 15.8 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 CRK33947.1 - 0.02 14.4 0.0 0.04 13.4 0.0 1.5 1 1 0 1 1 1 0 Putative methyltransferase CheR PF01739.18 CRK33947.1 - 0.076 12.5 0.0 8 5.9 0.0 2.3 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_16 PF10294.9 CRK33947.1 - 0.1 12.3 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase tRNA-synt_1 PF00133.22 CRK33950.1 - 1.6e-151 505.5 0.0 2.1e-151 505.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 CRK33950.1 - 5.1e-17 61.7 0.0 2.3e-09 36.5 0.0 3.2 3 0 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 CRK33950.1 - 3.1e-16 59.7 0.0 6.2e-16 58.7 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1b PF00579.25 CRK33950.1 - 0.25 10.6 0.0 6.4 6.0 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) zf-FPG_IleRS PF06827.14 CRK33950.1 - 0.47 10.4 4.4 1.1 9.2 4.4 1.7 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS DUF1007 PF06226.13 CRK33953.1 - 0.099 12.6 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1007) Alginate_lyase PF05426.12 CRK33955.1 - 2.2e-07 30.7 0.0 0.1 12.2 0.0 3.9 3 1 0 3 3 3 3 Alginate lyase Tail_spike_N PF18668.1 CRK33955.1 - 0.013 15.4 0.5 5.5 6.9 0.1 2.5 2 0 0 2 2 2 0 Tail spike TSP1/Gp66 receptor binding N-terminal domain DUF2990 PF11693.8 CRK33955.1 - 0.014 15.5 0.0 7.8 6.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2990) zf-H2C2_2 PF13465.6 CRK33955.1 - 0.26 11.8 1.4 30 5.3 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger double domain Nucleocapsid-N PF11030.8 CRK33957.1 - 0.0027 17.7 0.2 3.4 7.6 0.0 2.5 2 0 0 2 2 2 2 Nucleocapsid protein N RNA_pol_Rbc25 PF08292.12 CRK33957.1 - 0.3 11.3 1.0 0.83 9.9 1.0 1.7 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 Peptidase_S8 PF00082.22 CRK33959.1 - 5.9e-33 114.4 4.4 1.1e-15 57.7 0.4 2.4 2 0 0 2 2 2 2 Subtilase family Ank_2 PF12796.7 CRK33959.1 - 3.9e-08 33.8 0.0 0.00024 21.6 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) NAD_binding_10 PF13460.6 CRK33959.1 - 5.8e-08 32.8 0.4 2.7e-07 30.6 0.1 2.4 3 0 0 3 3 3 1 NAD(P)H-binding Ank PF00023.30 CRK33959.1 - 0.0021 18.4 0.0 0.06 13.8 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Dynein_AAA_lid PF17852.1 CRK33959.1 - 0.0022 18.1 0.0 4.9 7.3 0.0 3.0 2 0 0 2 2 2 2 Dynein heavy chain AAA lid domain Ank_3 PF13606.6 CRK33959.1 - 0.0028 18.0 0.0 2.3 9.0 0.0 3.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 CRK33959.1 - 0.0056 17.2 0.0 0.3 11.7 0.0 3.6 3 1 0 3 3 3 1 Ankyrin repeats (many copies) UNC-79 PF14776.6 CRK33959.1 - 0.011 14.5 0.0 2.7 6.7 0.0 2.1 2 0 0 2 2 2 0 Cation-channel complex subunit UNC-79 Ribosomal_L12 PF00542.19 CRK33959.1 - 0.032 14.6 5.5 4 7.9 0.5 2.9 2 0 0 2 2 2 0 Ribosomal protein L7/L12 C-terminal domain Ank_5 PF13857.6 CRK33959.1 - 0.065 13.6 0.0 0.5 10.8 0.0 2.3 1 1 1 2 2 2 0 Ankyrin repeats (many copies) DUF2345 PF10106.9 CRK33959.1 - 2.3 8.0 9.4 26 4.6 0.1 4.1 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2345) DUF963 PF06131.11 CRK33959.1 - 6.6 6.3 7.1 23 4.5 0.6 2.7 3 0 0 3 3 3 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) Ank_2 PF12796.7 CRK33961.1 - 8.2e-104 340.4 8.0 2e-12 47.5 0.6 13.4 6 3 8 15 15 15 13 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CRK33961.1 - 9e-74 243.0 12.3 2.3e-06 28.0 0.0 21.4 14 6 9 23 23 23 17 Ankyrin repeats (many copies) UPF0183 PF03676.14 CRK33961.1 - 2.7e-58 198.2 0.0 2.6e-28 99.5 0.0 4.1 3 1 0 3 3 3 3 Uncharacterised protein family (UPF0183) Ank_3 PF13606.6 CRK33961.1 - 1.8e-56 181.5 21.8 0.00059 20.1 0.0 25.7 29 0 0 29 29 29 11 Ankyrin repeat Ank PF00023.30 CRK33961.1 - 1.1e-51 171.1 32.1 0.00075 19.8 0.0 21.1 21 1 0 21 21 21 12 Ankyrin repeat Ank_5 PF13857.6 CRK33961.1 - 2.8e-50 167.7 24.7 9.6e-06 25.8 0.0 18.0 10 7 11 21 21 21 13 Ankyrin repeats (many copies) DUF676 PF05057.14 CRK33961.1 - 4.3e-06 26.4 0.0 0.00021 20.9 0.0 2.3 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Big_10 PF17964.1 CRK33961.1 - 0.04 13.9 0.1 12 5.8 0.0 2.5 2 0 0 2 2 2 0 Bacterial Ig domain DUF3689 PF12463.8 CRK33961.1 - 0.2 10.9 0.0 21 4.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3689) Ank_2 PF12796.7 CRK33962.1 - 5.8e-10 39.6 0.0 2.1e-05 25.0 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CRK33962.1 - 1.2e-05 25.3 0.0 0.29 11.8 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 CRK33962.1 - 4.1e-05 23.8 0.0 0.0078 16.6 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 CRK33962.1 - 0.00019 21.9 0.0 0.037 14.6 0.0 3.1 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 CRK33962.1 - 0.0012 19.2 0.0 0.067 13.5 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeats (many copies) FAM83 PF07894.12 CRK33962.1 - 0.082 12.4 1.6 17 4.8 0.0 2.4 2 0 0 2 2 2 0 FAM83 A-H MCPVI PF02993.14 CRK33963.1 - 0.019 14.8 0.5 0.022 14.6 0.5 1.0 1 0 0 1 1 1 0 Minor capsid protein VI RNA_pol_Rpb1_5 PF04998.17 CRK33965.1 - 1.1e-99 333.2 0.0 1.7e-99 332.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 CRK33965.1 - 3e-96 322.5 0.0 4.5e-96 321.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 CRK33965.1 - 3.1e-76 255.2 0.0 5.6e-76 254.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 CRK33965.1 - 6.4e-63 212.1 0.5 1.1e-62 211.3 0.5 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_7 PF04990.12 CRK33965.1 - 1e-47 161.5 3.5 7.5e-47 158.7 4.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_3 PF04983.18 CRK33965.1 - 1e-45 155.5 0.0 2.2e-45 154.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 CRK33965.1 - 6.5e-37 125.8 0.1 1.5e-36 124.6 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 CRK33965.1 - 0.012 15.9 5.1 0.012 15.9 5.1 14.0 9 4 5 15 15 15 0 RNA polymerase Rpb1 C-terminal repeat WD40 PF00400.32 CRK33966.1 - 3.2e-12 46.7 8.7 2.1e-05 25.2 0.2 3.8 3 1 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK33966.1 - 4.5e-08 33.3 0.2 0.024 14.9 0.0 3.5 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CRK33966.1 - 0.0038 17.1 0.0 0.064 13.1 0.0 2.1 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Thg1 PF04446.12 CRK33967.1 - 5.4e-53 178.3 0.0 8.6e-53 177.7 0.0 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 CRK33967.1 - 1.7e-50 170.3 0.3 2.4e-50 169.8 0.3 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain HMGL-like PF00682.19 CRK33969.1 - 1.9e-158 525.9 7.8 8.1e-79 264.9 1.0 2.3 2 0 0 2 2 2 2 HMGL-like Oxidored_FMN PF00724.20 CRK33969.1 - 0.0048 16.2 0.2 4.9 6.3 0.0 2.9 3 0 0 3 3 3 2 NADH:flavin oxidoreductase / NADH oxidase family MR_MLE_C PF13378.6 CRK33969.1 - 0.05 13.2 0.0 15 5.1 0.0 2.7 2 0 0 2 2 2 0 Enolase C-terminal domain-like DUF1310 PF07006.11 CRK33969.1 - 0.4 10.7 3.6 23 5.0 0.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF1310) Thg1C PF14413.6 CRK33970.1 - 1.2e-25 90.0 0.2 1.5e-25 89.7 0.2 1.1 1 0 0 1 1 1 1 Thg1 C terminal domain Bromodomain PF00439.25 CRK33973.1 - 4.7e-32 109.9 1.5 2.1e-15 56.5 0.3 2.5 2 0 0 2 2 2 2 Bromodomain Nop14 PF04147.12 CRK33973.1 - 0.031 12.5 19.4 0.055 11.7 19.4 1.4 1 0 0 1 1 1 0 Nop14-like family Astro_capsid_p PF12226.8 CRK33973.1 - 0.037 13.2 16.0 0.063 12.4 16.0 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DNA_pol_phi PF04931.13 CRK33973.1 - 0.19 9.8 28.3 0.3 9.1 28.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi Afi1 PF07792.12 CRK33973.1 - 0.25 11.8 13.6 2.4 8.7 6.8 2.7 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking CNDH2_C PF16858.5 CRK33973.1 - 0.54 10.1 14.8 0.12 12.3 11.0 1.9 1 1 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Cwf_Cwc_15 PF04889.12 CRK33973.1 - 2.8 7.6 25.1 0.061 13.1 16.7 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 CRK33973.1 - 4.4 6.5 25.3 9.2 5.5 25.3 1.5 1 0 0 1 1 1 0 NOA36 protein SAPS PF04499.15 CRK33973.1 - 9.2 4.9 10.0 13 4.4 7.7 2.1 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein CKS PF01111.19 CRK33974.1 - 2.2e-20 72.7 0.3 2.4e-20 72.6 0.3 1.0 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Zincin_1 PF06262.11 CRK33974.1 - 0.1 12.7 0.0 0.12 12.5 0.0 1.1 1 0 0 1 1 1 0 Zincin-like metallopeptidase ERO1 PF04137.15 CRK33975.1 - 2.8e-134 447.8 0.6 3.8e-134 447.4 0.0 1.5 2 0 0 2 2 2 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) BUD22 PF09073.10 CRK33975.1 - 0.18 11.1 8.3 0.27 10.5 8.3 1.1 1 0 0 1 1 1 0 BUD22 PBP1_TM PF14812.6 CRK33975.1 - 0.37 11.2 11.7 0.048 14.0 7.1 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cwf_Cwc_15 PF04889.12 CRK33975.1 - 0.72 9.5 11.5 1.5 8.5 11.5 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 CRK33975.1 - 1.3 8.3 14.0 2.5 7.4 14.0 1.4 1 0 0 1 1 1 0 NOA36 protein RRN3 PF05327.11 CRK33975.1 - 1.4 7.4 9.6 2.1 6.8 9.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF2457 PF10446.9 CRK33975.1 - 2.3 7.3 21.9 3.6 6.6 21.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Sporozoite_P67 PF05642.11 CRK33975.1 - 4.3 5.3 7.8 6.4 4.7 7.8 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen HVSL PF09749.9 CRK33976.1 - 6.4e-84 281.1 0.0 7.3e-84 281.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein COE1_HLH PF16423.5 CRK33977.1 - 0.018 14.7 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 Transcription factor COE1 helix-loop-helix domain CytochromB561_N PF09786.9 CRK33977.1 - 0.39 9.6 6.4 0.52 9.2 6.4 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal UDG PF03167.19 CRK33978.1 - 3.8e-19 69.2 0.0 6.3e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Pal1 PF08316.11 CRK33978.1 - 3.8e-05 24.5 0.0 7.9e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Pal1 cell morphology protein Pescadillo_N PF06732.11 CRK33979.1 - 6.1e-47 160.4 3.5 4.6e-42 144.5 0.5 2.2 2 0 0 2 2 2 2 Pescadillo N-terminus RRN9 PF10680.9 CRK33979.1 - 3.9e-13 49.5 0.2 3.9e-13 49.5 0.2 3.0 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor zf-C2H2_aberr PF17017.5 CRK33979.1 - 0.0077 16.4 1.7 0.11 12.7 2.1 2.1 1 1 1 2 2 2 1 Aberrant zinc-finger zf-C2H2 PF00096.26 CRK33979.1 - 0.84 10.2 14.3 0.086 13.3 4.0 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type Pex14_N PF04695.13 CRK33979.1 - 1.6 9.3 12.6 1.5 9.5 0.4 3.0 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Kinesin PF00225.23 CRK33980.1 - 7.5e-108 360.4 0.1 7.5e-108 360.4 0.1 2.1 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 CRK33980.1 - 1.6e-23 83.3 0.1 6.9e-23 81.2 0.0 2.2 2 0 0 2 2 2 1 Microtubule binding Microtub_bind PF13931.6 CRK33980.1 - 4.3e-08 33.6 0.9 4.3e-08 33.6 0.9 5.2 4 1 2 6 6 6 1 Kinesin-associated microtubule-binding Apolipoprotein PF01442.18 CRK33980.1 - 0.00015 21.7 14.4 0.00015 21.7 14.4 4.1 1 1 2 3 3 3 2 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 CRK33980.1 - 0.013 15.5 0.2 0.013 15.5 0.2 5.4 2 2 4 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus Kelch_3 PF13415.6 CRK33982.1 - 3.6e-34 116.4 10.4 6.2e-08 32.7 0.1 6.1 6 0 0 6 6 5 5 Galactose oxidase, central domain Kelch_5 PF13854.6 CRK33982.1 - 6.1e-33 112.3 8.4 2.1e-07 30.8 0.1 5.7 5 0 0 5 5 5 5 Kelch motif Kelch_1 PF01344.25 CRK33982.1 - 2.3e-32 110.3 12.1 3.3e-07 29.8 1.4 5.5 5 0 0 5 5 5 5 Kelch motif Kelch_4 PF13418.6 CRK33982.1 - 5.4e-29 99.9 14.1 3.4e-06 26.9 0.2 5.8 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.6 CRK33982.1 - 3e-28 97.1 10.3 2.3e-06 27.7 0.0 5.6 3 2 2 5 5 5 5 Kelch motif Kelch_2 PF07646.15 CRK33982.1 - 2.8e-26 90.4 8.8 1.9e-06 27.6 0.3 5.6 5 0 0 5 5 5 5 Kelch motif Helicase_C PF00271.31 CRK33982.1 - 1.5e-23 83.3 0.0 2.6e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CRK33982.1 - 2.5e-08 33.9 0.0 4e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase CENP-B_dimeris PF09026.10 CRK33982.1 - 0.074 13.4 16.2 1.1 9.7 2.2 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain PI3K_1B_p101 PF10486.9 CRK33982.1 - 0.64 7.7 2.8 1.2 6.9 2.8 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit GREB1 PF15782.5 CRK33982.1 - 2.2 5.3 9.9 3.3 4.7 9.9 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RskA PF10099.9 CRK33983.1 - 0.14 12.5 7.4 0.045 14.1 4.6 1.5 1 1 1 2 2 2 0 Anti-sigma-K factor rskA Kelch_5 PF13854.6 CRK33984.1 - 4.8e-40 135.0 12.5 1.1e-07 31.7 0.1 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.25 CRK33984.1 - 1.5e-37 127.0 15.5 1.8e-07 30.6 0.9 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 CRK33984.1 - 5.2e-36 122.3 14.4 2.4e-08 34.1 0.1 6.9 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.6 CRK33984.1 - 6.3e-33 112.0 14.5 1.3e-06 28.5 0.0 6.5 4 2 2 6 6 6 6 Kelch motif Kelch_4 PF13418.6 CRK33984.1 - 9.3e-33 112.0 17.5 2.8e-06 27.2 0.2 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.15 CRK33984.1 - 1.5e-31 107.2 12.6 2.9e-07 30.2 0.1 6.5 6 0 0 6 6 6 6 Kelch motif PBP1_TM PF14812.6 CRK33984.1 - 0.081 13.3 9.2 0.17 12.3 9.2 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.10 CRK33984.1 - 0.37 11.2 7.5 0.73 10.3 7.5 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PI3K_1B_p101 PF10486.9 CRK33984.1 - 1 7.1 5.2 1.4 6.6 5.2 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit SprA-related PF12118.8 CRK33984.1 - 2.9 6.9 11.2 4.8 6.2 11.2 1.2 1 0 0 1 1 1 0 SprA-related family FAM176 PF14851.6 CRK33984.1 - 3.4 7.3 5.7 6.2 6.5 5.7 1.4 1 0 0 1 1 1 0 FAM176 family zf-C2H2_aberr PF17017.5 CRK33988.1 - 1.4e-05 25.4 1.5 0.018 15.2 0.3 2.4 2 0 0 2 2 2 2 Aberrant zinc-finger zf-C2H2 PF00096.26 CRK33988.1 - 0.00026 21.2 10.0 0.089 13.3 0.7 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CRK33988.1 - 0.06 13.8 13.7 0.1 13.1 0.5 3.3 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2_jaz PF12171.8 CRK33988.1 - 0.14 12.5 1.6 6.3 7.2 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 CRK33988.1 - 7.2 7.7 23.3 0.15 13.0 0.6 4.0 4 0 0 4 4 4 0 C2H2-type zinc finger Kelch_4 PF13418.6 CRK33989.1 - 1.1e-27 95.7 11.4 6.3e-08 32.5 0.0 5.4 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 CRK33989.1 - 1e-23 82.8 6.9 5.9e-06 26.1 0.0 4.9 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 CRK33989.1 - 8e-22 76.7 2.7 0.00032 20.9 0.0 5.2 4 1 1 5 5 5 4 Kelch motif Kelch_3 PF13415.6 CRK33989.1 - 1e-19 70.3 7.3 2.1e-07 31.1 0.1 5.7 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_1 PF01344.25 CRK33989.1 - 1.2e-18 66.4 1.7 0.00011 21.6 0.0 5.1 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.15 CRK33989.1 - 1.1e-17 63.2 4.6 7e-05 22.6 0.0 5.2 5 0 0 5 5 5 4 Kelch motif BTB PF00651.31 CRK33989.1 - 8.1e-09 35.7 0.0 1.4e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 CRK33989.1 - 0.12 12.5 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 BTB And C-terminal Kelch ANAPC4_WD40 PF12894.7 CRK33990.1 - 8.8e-18 64.4 4.9 3.2e-05 24.1 0.3 4.3 2 1 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CRK33990.1 - 7.1e-17 61.5 18.8 0.00033 21.4 0.1 6.5 7 0 0 7 7 7 5 WD domain, G-beta repeat Ge1_WD40 PF16529.5 CRK33990.1 - 1.9e-06 27.1 0.1 0.00031 19.8 0.0 3.3 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 CRK33990.1 - 2e-06 27.8 0.2 0.00034 20.6 0.1 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Aldedh PF00171.22 CRK33991.1 - 2.1e-132 441.9 2.3 2.5e-132 441.7 2.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family BetaGal_dom3 PF13363.6 CRK33993.1 - 0.0011 18.5 0.0 7.9 6.1 0.0 3.3 3 0 0 3 3 3 3 Beta-galactosidase, domain 3 Fungal_trans PF04082.18 CRK33994.1 - 1.2e-06 27.7 0.6 2.6e-06 26.7 0.6 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK33994.1 - 4.3e-06 26.7 10.7 1.1e-05 25.4 10.7 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SAM_3 PF18016.1 CRK33994.1 - 0.15 11.9 0.1 30 4.5 0.0 2.6 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) PetM PF08041.11 CRK33994.1 - 0.51 10.0 1.3 31 4.3 0.1 2.5 2 0 0 2 2 2 0 PetM family of cytochrome b6f complex subunit 7 FA_hydroxylase PF04116.13 CRK33995.1 - 4.7e-16 59.3 16.0 4.7e-16 59.3 16.0 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily WD40 PF00400.32 CRK33996.1 - 1.1e-58 193.7 14.2 1.2e-08 35.4 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK33996.1 - 4.3e-14 52.6 0.0 0.0005 20.3 0.0 5.2 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Tup_N PF08581.10 CRK33996.1 - 4.9e-14 52.4 12.0 1.1e-13 51.3 12.0 1.6 1 0 0 1 1 1 1 Tup N-terminal Ge1_WD40 PF16529.5 CRK33996.1 - 2e-06 27.0 0.2 0.53 9.2 0.0 5.0 2 2 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 CRK33996.1 - 5.6e-05 22.6 0.0 0.61 9.4 0.0 4.4 4 1 1 5 5 5 2 WD40-like domain PD40 PF07676.12 CRK33996.1 - 0.0034 17.3 0.7 13 5.9 0.0 5.0 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Nup160 PF11715.8 CRK33996.1 - 0.0091 14.7 0.2 2.1 6.9 0.0 3.6 1 1 3 4 4 4 1 Nucleoporin Nup120/160 DUF3037 PF11236.8 CRK33996.1 - 0.012 16.0 0.6 0.023 15.1 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3037) Cytochrom_D1 PF02239.16 CRK33996.1 - 0.065 11.7 0.3 0.49 8.9 0.2 2.2 1 1 1 2 2 2 0 Cytochrome D1 heme domain SR-25 PF10500.9 CRK33997.1 - 5.2 6.6 22.1 0.89 9.1 8.9 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Aa_trans PF01490.18 CRK33998.1 - 7.9e-61 206.0 32.8 9.5e-61 205.7 32.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein POM121 PF15229.6 CRK33998.1 - 9.5 5.8 6.8 0.91 9.1 2.4 1.5 2 0 0 2 2 2 0 POM121 family Pkinase PF00069.25 CRK33999.1 - 7.5e-52 176.3 0.0 1.1e-51 175.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK33999.1 - 6.8e-29 100.9 0.0 1e-28 100.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CRK33999.1 - 3.2e-11 43.1 0.0 7.1e-09 35.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 CRK33999.1 - 0.0059 16.0 0.1 0.022 14.1 0.0 1.8 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family ABC1 PF03109.16 CRK33999.1 - 0.037 14.2 0.0 0.077 13.2 0.0 1.4 1 0 0 1 1 1 0 ABC1 family PAC1 PF16094.5 CRK33999.1 - 0.27 10.3 2.6 7.9 5.6 1.2 2.1 2 0 0 2 2 2 0 Proteasome assembly chaperone 4 Hydrolase PF00702.26 CRK34000.1 - 0.00058 20.2 0.0 0.0012 19.2 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Ribosomal_L23eN PF03939.13 CRK34001.1 - 4.8e-23 81.1 8.4 4.8e-23 81.1 8.4 2.6 2 1 1 3 3 3 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 CRK34001.1 - 1.9e-15 57.0 0.7 1.9e-15 57.0 0.7 1.9 2 1 0 2 2 2 1 Ribosomal protein L23 zf-Tim10_DDP PF02953.15 CRK34002.1 - 3.6e-22 77.8 1.1 4.7e-22 77.4 1.1 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger CorA PF01544.18 CRK34003.1 - 9.1e-46 156.5 0.0 1.2e-45 156.1 0.0 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein ALS2CR11 PF15729.5 CRK34003.1 - 0.081 12.1 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 candidate 11 tRNA-synt_2d PF01409.20 CRK34008.1 - 1.4e-48 165.6 0.1 1.5e-48 165.4 0.1 1.0 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.20 CRK34008.1 - 0.0057 15.8 0.1 0.17 10.9 0.0 2.1 1 1 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA_synthFbeta PF17759.1 CRK34008.1 - 0.0076 15.7 0.0 0.0084 15.6 0.0 1.1 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain DUF1938 PF09153.10 CRK34008.1 - 0.13 12.4 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1938) MR_MLE_C PF13378.6 CRK34010.1 - 7.9e-57 192.3 0.0 1.1e-56 191.9 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 CRK34010.1 - 0.019 14.1 0.0 0.026 13.7 0.0 1.3 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus Pribosyl_synth PF14572.6 CRK34012.1 - 8.3e-08 32.5 0.0 8.4e-08 32.5 0.0 1.0 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Na_H_Exchanger PF00999.21 CRK34013.1 - 1.7e-17 63.3 6.9 1.9e-17 63.1 6.9 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family ABC2_membrane_5 PF13346.6 CRK34013.1 - 0.36 10.4 7.4 0.42 10.1 1.6 2.0 1 1 1 2 2 2 0 ABC-2 family transporter protein Popeye PF04831.13 CRK34013.1 - 9.2 6.4 7.2 6.8 6.9 0.3 2.1 1 1 1 2 2 2 0 Popeye protein conserved region TBP PF00352.21 CRK34016.1 - 7.9e-09 35.4 0.0 1.2e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Transcription factor TFIID (or TATA-binding protein, TBP) PBP PF01161.20 CRK34017.1 - 7.4e-07 29.6 0.0 9.6e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein FAD-oxidase_C PF02913.19 CRK34018.1 - 1.2e-61 208.6 0.2 1.2e-61 208.6 0.2 1.9 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 CRK34018.1 - 1.6e-35 121.8 0.1 3.1e-35 120.9 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain Clr5 PF14420.6 CRK34018.1 - 2.8e-19 69.1 2.0 4.8e-19 68.3 0.6 2.2 2 0 0 2 2 2 1 Clr5 domain SPRY PF00622.28 CRK34018.1 - 1.1e-05 25.5 0.0 2.5e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 SPRY domain ECH_1 PF00378.20 CRK34019.1 - 3.2e-37 128.2 0.0 4e-37 127.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CRK34019.1 - 2.6e-22 79.8 0.1 5.3e-22 78.7 0.1 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase LNS2 PF08235.13 CRK34020.1 - 1.1e-93 312.9 0.0 1.5e-93 312.5 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 CRK34020.1 - 4.5e-43 145.4 0.0 2e-42 143.3 0.0 2.1 2 0 0 2 2 2 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.14 CRK34020.1 - 0.0041 16.7 0.0 0.18 11.4 0.0 2.5 2 0 0 2 2 2 1 HAD superfamily, subfamily IIIB (Acid phosphatase) PI3K_1B_p101 PF10486.9 CRK34020.1 - 0.67 7.7 11.1 1 7.1 11.1 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit TFIID-31kDa PF02291.15 CRK34022.1 - 1.1e-42 145.0 0.0 1.9e-42 144.2 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit DUF2722 PF10846.8 CRK34022.1 - 0.0081 15.2 9.5 0.0081 15.2 9.5 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) DUF601 PF04642.12 CRK34022.1 - 0.1 12.1 4.1 0.13 11.8 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF601 Spt20 PF12090.8 CRK34022.1 - 0.11 12.0 17.9 0.15 11.6 17.9 1.2 1 0 0 1 1 1 0 Spt20 family Presenilin PF01080.17 CRK34022.1 - 0.51 9.1 7.9 0.65 8.7 7.9 1.1 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 CRK34022.1 - 0.76 8.4 7.1 0.77 8.4 7.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PAT1 PF09770.9 CRK34022.1 - 1 7.5 10.3 1.1 7.4 10.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3464 PF11947.8 CRK34022.1 - 1.1 9.0 5.7 2 8.1 5.7 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF4551 PF15087.6 CRK34022.1 - 5.1 5.8 9.2 6.6 5.4 9.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Pex14_N PF04695.13 CRK34022.1 - 5.4 7.7 22.5 8.3 7.0 22.5 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SOG2 PF10428.9 CRK34022.1 - 7.2 5.7 15.5 8.1 5.5 15.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Hydin_ADK PF17213.3 CRK34022.1 - 7.7 6.7 11.3 13 6.0 11.3 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain CCDC53 PF10152.9 CRK34022.1 - 7.8 6.9 13.6 14 6.1 13.6 1.4 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex GREB1 PF15782.5 CRK34022.1 - 8.8 3.3 7.5 10 3.0 7.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Mucin PF01456.17 CRK34022.1 - 8.8 6.3 16.2 0.2 11.6 9.7 1.6 2 0 0 2 2 2 0 Mucin-like glycoprotein Histidinol_dh PF00815.20 CRK34023.1 - 2e-78 264.2 0.4 3.5e-78 263.4 0.4 1.3 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.18 CRK34023.1 - 6.1e-25 86.9 0.1 1.3e-24 85.8 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 CRK34023.1 - 1.2e-13 51.3 0.5 3.2e-13 49.9 0.5 1.8 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase Peptidase_M16_C PF05193.21 CRK34024.1 - 0.00011 22.2 0.0 0.0002 21.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain SNF2_N PF00176.23 CRK34027.1 - 1.2e-25 90.0 0.0 1.3e-25 89.9 0.0 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain ArfGap PF01412.18 CRK34028.1 - 2e-27 95.6 0.5 2.3e-27 95.4 0.5 1.1 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf TF_Zn_Ribbon PF08271.12 CRK34028.1 - 0.091 12.3 0.1 0.091 12.3 0.1 1.7 2 0 0 2 2 2 0 TFIIB zinc-binding Aldedh PF00171.22 CRK34029.1 - 1.1e-32 113.2 0.0 1.2e-32 113.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family TRF PF08558.10 CRK34030.1 - 2e-18 66.9 0.2 3.1e-18 66.3 0.2 1.3 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.31 CRK34030.1 - 4.4e-05 23.6 0.0 8.7e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain CENP-F_leu_zip PF10473.9 CRK34031.1 - 0.0066 16.5 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 KASH_CCD PF14662.6 CRK34031.1 - 0.089 12.6 0.6 0.5 10.2 0.3 2.2 1 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH HrpB7 PF09486.10 CRK34031.1 - 0.16 12.4 3.3 0.18 12.2 2.0 1.8 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) PRKG1_interact PF15898.5 CRK34031.1 - 1.1 10.2 4.4 95 4.0 0.1 3.4 2 1 0 3 3 3 0 cGMP-dependent protein kinase interacting domain Smg4_UPF3 PF03467.15 CRK34033.1 - 8.4e-44 149.6 0.0 8.4e-44 149.6 0.0 3.4 3 1 0 3 3 3 1 Smg-4/UPF3 family RRM_1 PF00076.22 CRK34033.1 - 1.5e-06 27.9 0.3 0.00041 20.1 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HTH_18 PF12833.7 CRK34033.1 - 0.054 13.8 0.9 0.54 10.6 0.1 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain RRM_7 PF16367.5 CRK34033.1 - 0.21 11.7 0.0 1.7 8.8 0.0 2.3 2 1 0 2 2 2 0 RNA recognition motif WD40 PF00400.32 CRK34038.1 - 1.8e-10 41.2 0.2 2.2e-08 34.6 0.2 2.9 3 0 0 3 3 3 1 WD domain, G-beta repeat Nup160 PF11715.8 CRK34038.1 - 0.00012 20.9 0.0 0.00012 20.9 0.0 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 CRK34038.1 - 0.00015 22.0 0.0 0.00047 20.4 0.0 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CRK34038.1 - 0.047 13.0 0.0 0.065 12.5 0.0 1.3 1 0 0 1 1 1 0 WD40-like domain GYF PF02213.16 CRK34046.1 - 9.1e-21 73.3 1.2 1.8e-20 72.3 0.2 1.9 2 0 0 2 2 2 1 GYF domain GYF_2 PF14237.6 CRK34046.1 - 0.00011 21.9 0.2 0.00028 20.6 0.0 1.7 2 0 0 2 2 2 1 GYF domain 2 Biotin_carb_C PF02785.19 CRK34055.1 - 3e-33 114.1 0.0 3.6e-33 113.9 0.0 1.1 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain PapC_C PF13953.6 CRK34056.1 - 0.055 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 PapC C-terminal domain SPX PF03105.19 CRK34058.1 - 4.6e-18 66.3 0.5 5.9e-18 65.9 0.5 1.1 1 0 0 1 1 1 1 SPX domain NIR_SIR PF01077.22 CRK34060.1 - 3.2e-06 26.7 0.0 4.2e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pectate_lyase PF03211.13 CRK34062.1 - 1.3e-37 129.3 0.6 1.6e-37 129.0 0.6 1.1 1 0 0 1 1 1 1 Pectate lyase HAD_2 PF13419.6 CRK34063.1 - 1.5e-18 67.5 0.0 2e-18 67.1 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CRK34063.1 - 5.2e-05 23.6 0.0 6.3e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CRK34063.1 - 0.00011 22.2 0.0 0.0002 21.3 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like NIF PF03031.18 CRK34063.1 - 0.0017 18.1 0.0 0.0038 17.0 0.0 1.5 1 1 1 2 2 2 1 NLI interacting factor-like phosphatase UDPG_MGDP_dh_C PF03720.15 CRK34063.1 - 0.077 13.4 0.0 0.41 11.1 0.0 2.1 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain GFO_IDH_MocA PF01408.22 CRK34064.1 - 6e-11 43.2 0.0 1.2e-10 42.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold CoA_binding_2 PF13380.6 CRK34064.1 - 0.03 14.8 0.0 0.064 13.7 0.0 1.5 1 0 0 1 1 1 0 CoA binding domain IglC PF11550.8 CRK34064.1 - 0.039 13.4 0.1 0.079 12.4 0.1 1.4 1 0 0 1 1 1 0 Intracellular growth locus C protein NAD_binding_3 PF03447.16 CRK34064.1 - 0.043 14.5 0.0 0.079 13.6 0.0 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Cellulase PF00150.18 CRK34064.1 - 0.049 13.1 0.1 0.082 12.3 0.1 1.4 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) LigB PF02900.18 CRK34064.1 - 0.05 12.7 0.1 0.076 12.1 0.1 1.2 1 0 0 1 1 1 0 Catalytic LigB subunit of aromatic ring-opening dioxygenase UNC-50 PF05216.13 CRK34066.1 - 0.0014 18.2 2.9 0.0014 18.2 2.9 1.8 2 0 0 2 2 2 1 UNC-50 family DUF4293 PF14126.6 CRK34066.1 - 0.0028 17.9 6.2 0.0032 17.7 6.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4293) MARVEL PF01284.23 CRK34066.1 - 0.023 14.7 12.9 0.028 14.4 12.9 1.1 1 0 0 1 1 1 0 Membrane-associating domain Neur_chan_memb PF02932.16 CRK34066.1 - 0.036 14.1 0.3 0.036 14.1 0.3 2.0 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region 7TMR-DISM_7TM PF07695.11 CRK34066.1 - 0.41 10.5 17.0 0.51 10.2 17.0 1.1 1 0 0 1 1 1 0 7TM diverse intracellular signalling FixP_N PF14715.6 CRK34066.1 - 2.8 7.7 11.4 5 7.0 0.1 3.3 3 0 0 3 3 3 0 N-terminal domain of cytochrome oxidase-cbb3, FixP DUF1129 PF06570.11 CRK34066.1 - 5.5 6.4 7.3 0.43 10.0 1.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) SCAMP PF04144.13 CRK34066.1 - 8.3 6.7 16.3 0.85 9.9 10.4 1.8 1 1 1 2 2 2 0 SCAMP family RDD PF06271.12 CRK34066.1 - 8.7 6.5 14.5 1.1 9.5 8.4 2.1 1 1 1 2 2 2 0 RDD family DUF1295 PF06966.12 CRK34069.1 - 0.0098 15.4 0.5 0.012 15.1 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) DALR_2 PF09190.11 CRK34069.1 - 0.11 13.0 0.1 0.24 11.9 0.1 1.6 1 0 0 1 1 1 0 DALR domain Trep_Strep PF09605.10 CRK34070.1 - 0.063 13.3 0.4 0.083 12.9 0.4 1.1 1 0 0 1 1 1 0 Hypothetical bacterial integral membrane protein (Trep_Strep) YtpI PF14007.6 CRK34070.1 - 0.12 12.5 0.2 0.18 11.9 0.2 1.3 1 0 0 1 1 1 0 YtpI-like protein Glu_synthase PF01645.17 CRK34071.1 - 1.6e-61 208.5 0.3 2.3e-61 208.0 0.3 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase VTC PF09359.10 CRK34071.1 - 3.9e-16 59.3 4.0 9.4e-16 58.0 0.2 2.2 2 0 0 2 2 2 1 VTC domain SPX PF03105.19 CRK34071.1 - 1.4e-05 25.2 22.1 0.00012 22.2 1.9 3.5 1 1 2 3 3 3 2 SPX domain Tti2 PF10521.9 CRK34071.1 - 0.082 12.4 0.6 0.23 11.0 0.2 1.8 2 0 0 2 2 2 0 Tti2 family BLOC1_2 PF10046.9 CRK34071.1 - 0.1 12.9 1.7 0.24 11.7 1.7 1.6 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SLBP_RNA_bind PF15247.6 CRK34071.1 - 0.13 12.4 0.9 0.32 11.1 0.2 1.9 2 0 0 2 2 2 0 Histone RNA hairpin-binding protein RNA-binding domain Apc15p PF05841.11 CRK34072.1 - 4.4e-06 27.5 0.2 8.2e-06 26.6 0.2 1.4 1 0 0 1 1 1 1 Apc15p protein CNDH2_C PF16858.5 CRK34072.1 - 0.014 15.3 2.4 0.017 15.0 2.4 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Seryl_tRNA_N PF02403.22 CRK34072.1 - 0.06 13.6 0.1 0.086 13.1 0.1 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Cwf_Cwc_15 PF04889.12 CRK34072.1 - 0.39 10.4 10.1 0.56 9.9 10.1 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF4148 PF13663.6 CRK34072.1 - 1.1 9.5 3.6 3.1 8.1 3.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4148) Nop14 PF04147.12 CRK34072.1 - 6 4.9 14.3 6.9 4.7 14.3 1.0 1 0 0 1 1 1 0 Nop14-like family G-patch PF01585.23 CRK34073.1 - 2.8e-11 43.1 0.9 2.8e-11 43.1 0.9 1.7 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 CRK34073.1 - 6.7e-06 26.1 0.2 6.7e-06 26.1 0.2 2.5 1 1 1 2 2 2 1 G-patch domain ATP-synt_E PF05680.12 CRK34073.1 - 0.0047 17.2 2.2 0.0067 16.8 2.2 1.2 1 0 0 1 1 1 1 ATP synthase E chain BES1_N PF05687.13 CRK34073.1 - 2.7 8.4 6.4 0.35 11.2 0.8 2.0 2 0 0 2 2 2 0 BES1/BZR1 plant transcription factor, N-terminal HEAT PF02985.22 CRK34074.1 - 0.038 14.2 0.3 0.16 12.3 0.0 2.2 3 0 0 3 3 3 0 HEAT repeat HEAT_2 PF13646.6 CRK34074.1 - 0.079 13.4 0.0 0.25 11.7 0.0 1.9 1 1 1 2 2 2 0 HEAT repeats DEC-1_N PF04625.13 CRK34075.1 - 6.6 5.6 7.3 6.7 5.6 7.3 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region ELO PF01151.18 CRK34076.1 - 2.4e-13 50.2 0.1 2.7e-13 50.0 0.1 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family Aldo_ket_red PF00248.21 CRK34077.1 - 3.7e-33 115.0 0.0 4.4e-33 114.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family RRM_1 PF00076.22 CRK34079.1 - 2.6e-16 59.2 0.0 3.7e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Coq4 PF05019.13 CRK34080.1 - 4.1e-58 196.3 0.0 4.5e-58 196.2 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Glyco_hydro_61 PF03443.14 CRK34082.1 - 2.5e-46 158.2 0.2 2.8e-46 158.0 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Gly_kinase PF02595.15 CRK34085.1 - 0.0081 15.2 0.0 0.011 14.8 0.0 1.1 1 0 0 1 1 1 1 Glycerate kinase family FAD_binding_8 PF08022.12 CRK34086.1 - 2.5e-21 75.8 0.0 4e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 CRK34086.1 - 0.00014 22.0 1.6 0.00026 21.1 1.6 1.5 1 0 0 1 1 1 1 Ferric reductase like transmembrane component RPN7 PF10602.9 CRK34088.1 - 1.2e-32 113.0 0.1 1.4e-32 112.8 0.1 1.0 1 0 0 1 1 1 1 26S proteasome subunit RPN7 Ribophorin_I PF04597.14 CRK34089.1 - 2.2e-56 192.0 1.5 2.4e-56 191.8 1.5 1.0 1 0 0 1 1 1 1 Ribophorin I FAD_binding_1 PF00667.20 CRK34092.1 - 0.23 11.0 0.0 0.23 11.0 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain ABC_tran PF00005.27 CRK34094.1 - 1.1e-06 29.2 0.1 1.4e-06 28.9 0.1 1.2 1 0 0 1 1 1 1 ABC transporter Ploopntkinase3 PF18751.1 CRK34094.1 - 0.009 15.9 0.0 0.011 15.7 0.0 1.1 1 0 0 1 1 1 1 P-loop Nucleotide Kinase3 AAA_22 PF13401.6 CRK34094.1 - 0.092 13.0 0.0 0.12 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 CRK34094.1 - 0.1 12.1 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 CRK34094.1 - 0.12 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase MS_channel PF00924.18 CRK34095.1 - 3.5e-10 39.8 4.9 4.1e-10 39.5 4.9 1.0 1 0 0 1 1 1 1 Mechanosensitive ion channel Pkinase PF00069.25 CRK34098.1 - 2.4e-23 82.9 0.0 2.7e-23 82.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK34098.1 - 1.3e-13 50.8 0.0 1.7e-13 50.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase adh_short PF00106.25 CRK34099.1 - 6.4e-07 29.0 0.0 0.0026 17.2 0.0 2.3 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CRK34099.1 - 0.003 17.1 0.0 0.033 13.8 0.0 2.2 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase CK_II_beta PF01214.18 CRK34100.1 - 1.3e-39 135.9 0.4 1.5e-39 135.7 0.4 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Afi1 PF07792.12 CRK34105.1 - 1.4e-48 164.7 1.7 2.5e-48 163.9 1.7 1.4 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.10 CRK34105.1 - 1.5e-36 124.8 0.0 2.8e-36 123.9 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 CRK34105.1 - 8.7e-08 31.2 0.1 0.018 13.7 0.0 3.9 3 1 1 4 4 4 2 Transport protein Avl9 Astro_capsid_p PF12226.8 CRK34105.1 - 0.00039 19.7 6.8 0.00062 19.0 6.8 1.2 1 0 0 1 1 1 1 Turkey astrovirus capsid protein Cwf_Cwc_15 PF04889.12 CRK34105.1 - 0.0077 16.0 12.8 0.014 15.1 12.8 1.3 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DUF2347 PF09804.9 CRK34105.1 - 0.036 13.6 0.0 0.14 11.7 0.0 2.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) Nop53 PF07767.11 CRK34105.1 - 0.12 11.8 9.8 0.19 11.1 9.8 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF1168 PF06658.12 CRK34105.1 - 0.19 11.5 12.0 0.38 10.6 12.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Nop14 PF04147.12 CRK34105.1 - 0.24 9.6 14.3 0.36 9.0 14.3 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4746 PF15928.5 CRK34105.1 - 0.38 10.1 4.4 0.6 9.5 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) QWRF PF04484.12 CRK34105.1 - 2 8.1 4.7 3.2 7.4 4.7 1.2 1 0 0 1 1 1 0 QWRF family RNA_pol_3_Rpc31 PF11705.8 CRK34105.1 - 2.9 8.1 19.6 5.5 7.2 19.6 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Esterase PF00756.20 CRK34107.1 - 3.8e-47 161.1 0.0 5.8e-47 160.5 0.0 1.2 1 0 0 1 1 1 1 Putative esterase RNA_pol_Rpb6 PF01192.22 CRK34107.1 - 2.7e-16 59.2 0.2 4.7e-16 58.4 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb6 Esterase_phd PF10503.9 CRK34107.1 - 4.2e-05 23.2 0.0 0.00012 21.6 0.0 1.7 1 1 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 CRK34107.1 - 0.0018 17.8 0.1 0.0094 15.4 0.0 2.2 3 0 0 3 3 3 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 CRK34107.1 - 0.013 14.8 0.0 0.029 13.6 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CRK34107.1 - 0.015 15.9 0.1 0.045 14.3 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 CRK34107.1 - 0.019 13.9 0.0 0.043 12.7 0.0 1.5 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_2 PF02230.16 CRK34107.1 - 0.039 13.8 0.0 0.077 12.8 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DUF2534 PF10749.9 CRK34107.1 - 0.14 12.3 0.3 0.33 11.1 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2534) zf-C2H2 PF00096.26 CRK34110.1 - 1.3e-25 88.4 57.8 0.00054 20.3 0.1 10.4 10 0 0 10 10 10 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CRK34110.1 - 3e-16 58.7 60.0 0.096 13.6 0.2 10.8 11 0 0 11 11 11 8 C2H2-type zinc finger FOXP-CC PF16159.5 CRK34110.1 - 3.8e-09 37.1 33.0 0.0006 20.4 0.4 8.0 6 2 2 8 8 8 3 FOXP coiled-coil domain zf-met PF12874.7 CRK34110.1 - 5e-07 29.9 19.3 0.32 11.4 0.0 7.8 9 0 0 9 9 8 2 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 CRK34110.1 - 8.9e-07 29.1 20.0 0.0021 18.3 4.9 5.3 3 2 2 5 5 5 2 C2H2-type zinc ribbon zf-H2C2_2 PF13465.6 CRK34110.1 - 1.3e-06 28.5 59.3 0.0051 17.2 0.9 10.9 11 1 0 11 11 11 4 Zinc-finger double domain zf-C2H2_jaz PF12171.8 CRK34110.1 - 1.5e-06 28.3 29.3 1.8 8.9 1.4 8.6 10 0 0 10 10 9 4 Zinc-finger double-stranded RNA-binding zf-C2H2_aberr PF17017.5 CRK34110.1 - 1.2e-05 25.5 15.0 0.078 13.1 1.8 4.7 4 1 0 5 5 5 3 Aberrant zinc-finger DUF4187 PF13821.6 CRK34110.1 - 0.038 13.8 2.7 0.096 12.5 0.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) zf_Hakai PF18408.1 CRK34110.1 - 0.51 10.1 0.0 0.51 10.1 0.0 8.0 10 0 0 10 10 10 0 C2H2 Hakai zinc finger domain zf_ZIC PF18366.1 CRK34110.1 - 0.98 9.6 0.0 0.98 9.6 0.0 6.2 8 0 0 8 8 8 0 Zic proteins zinc finger domain Zip PF02535.22 CRK34112.1 - 8.1e-25 87.7 20.5 1.1e-24 87.4 18.1 2.1 2 1 0 2 2 2 1 ZIP Zinc transporter Endonuclease_NS PF01223.23 CRK34114.1 - 2.6e-66 223.7 0.0 3.2e-66 223.4 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease YbgS PF13985.6 CRK34114.1 - 0.22 11.8 0.3 0.36 11.1 0.3 1.4 1 0 0 1 1 1 0 YbgS-like protein Stomoxyn PF11585.8 CRK34114.1 - 0.44 10.6 2.3 0.77 9.8 2.3 1.4 1 0 0 1 1 1 0 Insect antimicrobial peptide, stomoxyn Endonuclease_NS PF01223.23 CRK34116.1 - 4.1e-15 56.2 0.0 4.2e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease WD40 PF00400.32 CRK34118.1 - 4e-54 179.4 53.2 8.6e-05 23.2 1.0 13.3 13 0 0 13 13 13 11 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK34118.1 - 1.4e-22 79.8 0.3 0.39 11.1 0.0 10.9 3 2 8 11 11 11 7 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CRK34118.1 - 0.00035 20.5 0.2 7.5 6.4 0.0 4.5 2 2 0 4 4 4 2 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 CRK34118.1 - 0.0029 16.0 0.0 1.8 6.8 0.0 2.3 2 0 0 2 2 2 2 WD repeat-containing and planar cell polarity effector protein Fritz SdiA-regulated PF06977.11 CRK34118.1 - 0.0039 16.5 0.0 4.6 6.4 0.0 2.9 3 0 0 3 3 3 2 SdiA-regulated Ge1_WD40 PF16529.5 CRK34118.1 - 0.0063 15.5 0.8 37 3.1 0.0 4.9 2 2 5 7 7 7 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Collagen PF01391.18 CRK34118.1 - 0.0086 15.8 13.5 0.057 13.2 1.8 2.7 2 0 0 2 2 2 2 Collagen triple helix repeat (20 copies) BBE PF08031.12 CRK34118.1 - 0.011 15.9 0.0 7.9 6.7 0.0 2.5 2 0 0 2 2 2 0 Berberine and berberine like VID27 PF08553.10 CRK34118.1 - 0.028 13.5 0.0 7.8 5.4 0.0 2.3 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain MBOAT PF03062.19 CRK34121.1 - 1.5e-19 70.6 17.7 1.5e-19 70.6 17.7 1.9 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 CRK34121.1 - 0.00043 20.5 2.2 0.0013 18.9 2.2 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family ICMT PF04140.14 CRK34123.1 - 3.9e-27 94.5 0.5 3.9e-27 94.5 0.5 1.9 2 1 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 CRK34123.1 - 1e-11 45.2 1.7 2.8e-11 43.7 1.7 1.8 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.12 CRK34123.1 - 5.9e-05 22.7 1.5 7.6e-05 22.3 1.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Hexapep_2 PF14602.6 CRK34124.1 - 1e-11 44.3 13.0 1e-10 41.2 3.6 3.1 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 CRK34124.1 - 1.6e-11 43.5 12.4 1.8e-09 37.0 3.9 3.5 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Mac PF12464.8 CRK34124.1 - 2.5e-09 37.2 0.4 5.7e-09 36.1 0.4 1.6 1 0 0 1 1 1 1 Maltose acetyltransferase Tmemb_170 PF10190.9 CRK34125.1 - 9e-34 116.0 27.7 1.8e-19 70.0 10.8 2.6 3 0 0 3 3 3 2 Putative transmembrane protein 170 Hexapep_2 PF14602.6 CRK34126.1 - 2.8e-14 52.6 13.6 1e-11 44.3 3.6 3.3 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 CRK34126.1 - 5.8e-14 51.2 11.7 1.8e-10 40.1 3.9 3.5 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) TPT PF03151.16 CRK34128.1 - 8.2e-35 120.6 17.1 9.9e-35 120.3 17.1 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 CRK34128.1 - 0.00028 20.2 21.5 0.0016 17.7 21.4 2.3 1 1 1 2 2 2 1 UAA transporter family BTP PF05232.12 CRK34128.1 - 0.083 13.0 3.9 13 5.9 1.7 3.3 2 0 0 2 2 2 0 Chlorhexidine efflux transporter EamA PF00892.20 CRK34128.1 - 0.26 11.4 36.8 1.7 8.8 12.2 2.3 2 1 0 2 2 2 0 EamA-like transporter family DUF2235 PF09994.9 CRK34130.1 - 1.5e-22 80.3 0.3 2.1e-22 79.8 0.3 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) MMR_HSR1_Xtn PF16897.5 CRK34132.1 - 7.1e-38 128.9 2.0 1.2e-37 128.1 1.3 1.8 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 CRK34132.1 - 8.6e-20 70.9 0.0 3e-19 69.2 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 CRK34132.1 - 2.3e-19 69.2 0.0 4.9e-19 68.1 0.0 1.6 1 0 0 1 1 1 1 TGS domain Ank_2 PF12796.7 CRK34132.1 - 8.8e-14 51.9 0.2 3e-09 37.3 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CRK34132.1 - 7.3e-09 36.0 0.0 1.3e-05 25.6 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 CRK34132.1 - 1.7e-08 34.6 0.1 0.0036 17.7 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 CRK34132.1 - 2.2e-08 33.7 0.0 0.002 18.4 0.0 3.8 3 0 0 3 3 3 1 Ankyrin repeat FeoB_N PF02421.18 CRK34132.1 - 5.2e-08 32.6 0.0 1.4e-07 31.2 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B Steroid_dh PF02544.16 CRK34132.1 - 6.8e-08 32.6 0.0 1.5e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase Ank_5 PF13857.6 CRK34132.1 - 1.1e-06 28.8 0.5 0.02 15.2 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) MeaB PF03308.16 CRK34132.1 - 0.038 13.0 0.1 0.14 11.1 0.1 1.9 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 CRK34132.1 - 0.39 10.8 0.0 0.39 10.8 0.0 4.4 2 2 1 4 4 2 0 Dynamin family DUF2235 PF09994.9 CRK34135.1 - 4.3e-44 151.0 0.0 4.9e-44 150.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Steroid_dh PF02544.16 CRK34136.1 - 2.6e-14 53.4 0.3 2.6e-14 53.4 0.3 1.9 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase Ank_2 PF12796.7 CRK34137.1 - 2e-22 79.5 0.3 1.7e-11 44.6 0.1 3.0 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CRK34137.1 - 1.1e-12 48.1 0.0 0.0048 17.5 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 CRK34137.1 - 1e-10 41.5 1.2 0.0023 18.3 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 CRK34137.1 - 2.1e-09 36.8 0.7 0.0043 17.5 0.0 4.9 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 CRK34137.1 - 5.4e-08 33.0 2.2 0.0089 16.3 0.2 4.2 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Pyr_redox_2 PF07992.14 CRK34137.1 - 0.05 12.8 0.0 0.13 11.5 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CENP-B_N PF04218.13 CRK34138.1 - 2.5e-09 36.6 0.2 6.8e-06 25.6 0.0 2.9 3 0 0 3 3 3 2 CENP-B N-terminal DNA-binding domain HTH_Tnp_Tc5 PF03221.16 CRK34138.1 - 4.3e-08 33.1 0.2 2.9e-07 30.4 0.1 2.3 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_Crp_2 PF13545.6 CRK34138.1 - 0.00015 21.7 0.0 0.026 14.5 0.0 2.6 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain MarR PF01047.22 CRK34138.1 - 0.00034 20.5 0.0 0.051 13.5 0.0 2.8 2 0 0 2 2 2 1 MarR family Sigma70_r4 PF04545.16 CRK34138.1 - 0.0005 19.5 0.0 0.099 12.2 0.0 2.4 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_38 PF13936.6 CRK34138.1 - 0.014 15.1 0.0 0.13 12.0 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain MarR_2 PF12802.7 CRK34138.1 - 0.014 15.2 0.0 0.93 9.4 0.0 3.1 3 0 0 3 3 3 0 MarR family HTH_23 PF13384.6 CRK34138.1 - 0.021 14.6 0.0 0.32 10.8 0.0 2.5 2 0 0 2 2 2 0 Homeodomain-like domain HTH_24 PF13412.6 CRK34138.1 - 0.024 14.2 0.0 0.58 9.8 0.0 2.8 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_4 PF13613.6 CRK34138.1 - 0.095 12.4 0.0 0.7 9.7 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix of DDE superfamily endonuclease HTH_3 PF01381.22 CRK34138.1 - 0.098 12.7 0.0 2.6 8.2 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix HTH_WhiA PF02650.14 CRK34138.1 - 0.15 12.4 0.0 6.6 7.1 0.0 2.5 2 0 0 2 2 2 0 WhiA C-terminal HTH domain HTH_37 PF13744.6 CRK34138.1 - 4 7.4 0.0 4 7.4 0.0 3.3 4 0 0 4 4 3 0 Helix-turn-helix domain PXA PF02194.15 CRK34139.1 - 2.7e-48 164.3 2.6 2.8e-48 164.3 1.4 1.6 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.12 CRK34139.1 - 0.032 14.8 0.1 0.4 11.3 0.0 2.7 4 0 0 4 4 4 0 Sorting nexin C terminal UBM PF14377.6 CRK34140.1 - 0.07 12.6 0.4 0.15 11.6 0.4 1.5 1 0 0 1 1 1 0 Ubiquitin binding region CPSF_A PF03178.15 CRK34140.1 - 0.21 10.8 0.1 0.38 10.0 0.1 1.4 1 0 0 1 1 1 0 CPSF A subunit region PXA PF02194.15 CRK34141.1 - 1.2e-47 162.3 1.0 2.3e-47 161.4 1.0 1.5 1 0 0 1 1 1 1 PXA domain zf-Mss51 PF13824.6 CRK34141.1 - 1.2e-26 92.6 5.2 1.2e-26 92.6 5.2 1.8 2 0 0 2 2 2 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.18 CRK34141.1 - 1.4 9.1 3.1 0.9 9.7 0.2 2.2 2 0 0 2 2 2 0 MYND finger MMS1_N PF10433.9 CRK34142.1 - 1.1e-180 601.5 0.0 1.5e-96 323.9 0.0 3.3 2 1 1 3 3 3 3 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 CRK34142.1 - 5.8e-180 597.6 0.0 2e-76 257.4 0.0 3.9 3 1 1 4 4 4 3 CPSF A subunit region TruB_C PF09142.11 CRK34142.1 - 0.1 12.4 4.0 1.3e+02 2.5 0.0 5.3 4 1 1 5 5 5 0 tRNA Pseudouridine synthase II, C terminal UBM PF14377.6 CRK34142.1 - 0.26 10.8 7.7 1.8 8.1 0.6 3.7 3 0 0 3 3 3 0 Ubiquitin binding region LysM PF01476.20 CRK34143.1 - 0.00019 21.4 0.0 0.00031 20.7 0.0 1.3 1 0 0 1 1 1 1 LysM domain zf-C3HC4_3 PF13920.6 CRK34143.1 - 3.9 7.4 10.5 0.15 12.0 4.0 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) WSC PF01822.19 CRK34144.1 - 1.3e-32 111.8 32.7 1.8e-18 66.5 9.8 5.0 5 0 0 5 5 5 3 WSC domain WSC PF01822.19 CRK34145.1 - 1.3e-30 105.4 31.6 1.3e-17 63.8 9.2 5.0 4 1 0 4 4 4 2 WSC domain Metallophos PF00149.28 CRK34145.1 - 1.2e-22 81.4 0.0 2.5e-22 80.4 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PCI PF01399.27 CRK34145.1 - 1.7e-07 31.7 0.5 4.5e-07 30.3 0.0 2.0 2 0 0 2 2 2 1 PCI domain LysM PF01476.20 CRK34145.1 - 0.014 15.5 0.0 0.029 14.4 0.0 1.5 1 0 0 1 1 1 0 LysM domain Rdx PF10262.9 CRK34146.1 - 7.2e-36 122.2 0.5 7.8e-14 51.6 0.0 3.2 2 1 1 3 3 3 3 Rdx family G-gamma PF00631.22 CRK34146.1 - 2.5e-06 27.4 0.5 4.7e-06 26.5 0.5 1.4 1 0 0 1 1 1 1 GGL domain PKD PF00801.20 CRK34146.1 - 4.5e-06 26.4 0.0 0.077 12.8 0.0 2.7 2 0 0 2 2 2 2 PKD domain SPATA48 PF15073.6 CRK34146.1 - 0.0049 17.2 0.8 3.1 8.1 0.1 2.7 2 1 0 2 2 2 2 Spermatogenesis-associated protein 48 Big_9 PF17963.1 CRK34146.1 - 0.12 13.1 11.6 1.2 10.0 0.3 3.4 3 0 0 3 3 3 0 Bacterial Ig domain PCI PF01399.27 CRK34147.1 - 2.1e-08 34.6 0.4 1.2e-07 32.2 0.0 2.3 2 0 0 2 2 2 1 PCI domain DUF4754 PF15946.5 CRK34147.1 - 0.12 12.7 0.0 0.37 11.1 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4754) G-gamma PF00631.22 CRK34148.1 - 1e-24 86.3 0.0 1.3e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 GGL domain Rdx PF10262.9 CRK34149.1 - 3.5e-33 113.6 0.0 4.9e-33 113.1 0.0 1.2 1 0 0 1 1 1 1 Rdx family Metallophos PF00149.28 CRK34150.1 - 1.8e-08 35.1 0.0 2.5e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TERT_thumb PF17984.1 CRK34150.1 - 0.16 11.9 0.1 0.2 11.5 0.1 1.1 1 0 0 1 1 1 0 Telomerase reverse transcriptase thumb DNA binding domain zf-HC5HC2H_2 PF13832.6 CRK34151.1 - 1.8e-33 115.0 7.2 1.8e-33 115.0 7.2 2.5 2 0 0 2 2 2 1 PHD-zinc-finger like domain EPL1 PF10513.9 CRK34151.1 - 5.7e-31 108.0 0.1 1e-30 107.2 0.1 1.4 1 0 0 1 1 1 1 Enhancer of polycomb-like zf-HC5HC2H PF13771.6 CRK34151.1 - 3.6e-26 91.2 6.8 3.6e-26 91.2 6.8 2.6 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.6 CRK34151.1 - 3.7e-14 52.0 1.9 3.7e-14 52.0 1.9 2.3 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 CRK34151.1 - 7.6e-09 35.3 24.4 1.4e-08 34.5 9.5 2.6 2 0 0 2 2 2 2 PHD-finger zf-PHD-like PF15446.6 CRK34151.1 - 5.9 6.5 14.2 0.038 13.6 2.6 2.3 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain LRR_8 PF13855.6 CRK34152.1 - 2.1e-14 53.0 14.2 4.3e-07 29.6 2.4 3.2 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 CRK34152.1 - 1.7e-13 50.5 2.2 0.0058 17.0 0.2 3.6 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CRK34152.1 - 0.00011 22.3 5.6 40 5.3 0.2 5.9 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_9 PF14580.6 CRK34152.1 - 0.01 15.3 0.3 0.037 13.5 0.2 1.8 1 1 0 1 1 1 0 Leucine-rich repeat LRR_6 PF13516.6 CRK34152.1 - 0.041 13.9 12.8 2 8.7 0.1 5.1 4 1 1 5 5 5 0 Leucine Rich repeat LAT PF15234.6 CRK34153.1 - 1.1 8.9 2.9 1.9 8.1 2.9 1.3 1 0 0 1 1 1 0 Linker for activation of T-cells DHFR_1 PF00186.19 CRK34154.1 - 9.4e-27 93.7 0.0 3.5e-26 91.8 0.0 2.0 1 1 0 1 1 1 1 Dihydrofolate reductase ASCH PF04266.14 CRK34154.1 - 0.027 15.0 0.0 0.047 14.3 0.0 1.4 1 0 0 1 1 1 0 ASCH domain MFS_1 PF07690.16 CRK34155.1 - 9.1e-14 51.1 28.2 9.1e-14 51.1 28.2 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily Luteo_Vpg PF01659.16 CRK34155.1 - 0.97 9.8 4.6 2.2 8.7 4.6 1.5 1 0 0 1 1 1 0 Luteovirus putative VPg genome linked protein Biotin_lipoyl PF00364.22 CRK34156.1 - 2.3e-21 75.4 0.3 4.4e-21 74.5 0.3 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 CRK34156.1 - 2.7e-08 34.0 0.0 1.1e-07 32.0 0.0 2.1 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 CRK34156.1 - 0.0001 22.0 0.0 0.00053 19.8 0.0 2.1 2 0 0 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.6 CRK34156.1 - 0.036 14.8 0.3 0.57 10.9 0.0 2.5 1 1 1 2 2 2 0 HlyD family secretion protein ArenaCapSnatch PF17296.2 CRK34156.1 - 0.17 11.3 0.0 0.26 10.7 0.0 1.2 1 0 0 1 1 1 0 Arenavirus cap snatching domain CoA_transf_3 PF02515.17 CRK34157.1 - 4.4e-38 131.4 0.0 5.1e-34 118.0 0.0 2.2 2 0 0 2 2 2 2 CoA-transferase family III Fungal_trans PF04082.18 CRK34158.1 - 1.9e-23 82.9 0.2 3e-23 82.2 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK34158.1 - 2.9e-07 30.5 12.4 6.7e-07 29.3 12.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dioxygenase_C PF00775.21 CRK34159.1 - 7.3e-44 149.4 0.0 9.9e-44 148.9 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 CRK34159.1 - 1.1e-28 98.8 0.1 1.8e-28 98.1 0.1 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 CRK34159.1 - 0.00044 20.5 0.0 0.0009 19.5 0.0 1.5 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain OPT PF03169.15 CRK34160.1 - 5.3e-182 606.7 48.6 6.1e-182 606.5 48.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein ketoacyl-synt PF00109.26 CRK34161.1 - 1.3e-61 208.4 4.8 6.8e-61 206.0 0.3 2.4 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 CRK34161.1 - 2.4e-37 127.5 1.4 4.9e-37 126.6 1.4 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Ubiq_cyt_C_chap PF03981.12 CRK34161.1 - 1.4e-29 103.0 1.9 6.8e-29 100.8 1.9 2.1 2 0 0 2 2 2 1 Ubiquinol-cytochrome C chaperone Thiolase_N PF00108.23 CRK34161.1 - 3.7e-06 26.5 0.7 5.3e-05 22.7 0.1 2.2 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CRK34161.1 - 0.016 14.9 0.5 0.016 14.9 0.5 2.6 2 2 1 3 3 3 0 Thiolase, C-terminal domain ThiF PF00899.21 CRK34163.1 - 5e-29 101.4 0.0 7.1e-29 100.9 0.0 1.1 1 0 0 1 1 1 1 ThiF family SRI PF08236.11 CRK34164.1 - 8e-20 70.8 8.7 1.9e-19 69.6 8.7 1.7 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.28 CRK34164.1 - 1.4e-16 61.4 0.2 1.4e-16 61.4 0.2 3.5 3 1 0 3 3 3 1 SET domain AWS PF17907.1 CRK34164.1 - 5.4e-11 42.3 7.4 5.4e-11 42.3 7.4 2.1 2 0 0 2 2 2 1 AWS domain Med26 PF08711.11 CRK34164.1 - 4.7e-05 23.3 0.1 0.00012 22.0 0.1 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain ROK PF00480.20 CRK34165.1 - 0.078 12.4 0.0 0.096 12.2 0.0 1.1 1 0 0 1 1 1 0 ROK family HNH_2 PF13391.6 CRK34166.1 - 1e-05 25.6 0.1 0.00072 19.6 0.0 2.9 2 0 0 2 2 2 1 HNH endonuclease CRISPR_Cas2 PF09827.9 CRK34166.1 - 0.0026 17.9 0.0 4.1 7.7 0.0 2.8 3 0 0 3 3 3 2 CRISPR associated protein Cas2 Aminotran_3 PF00202.21 CRK34167.1 - 3e-115 385.1 0.0 3.4e-115 384.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III HNH_2 PF13391.6 CRK34168.1 - 4.7e-05 23.4 1.4 8.6e-05 22.6 0.1 2.2 2 1 0 2 2 2 1 HNH endonuclease Voltage_CLC PF00654.20 CRK34169.1 - 1.7e-168 560.4 54.2 1.1e-85 288.0 24.6 2.3 2 0 0 2 2 2 2 Voltage gated chloride channel Aminotran_3 PF00202.21 CRK34169.1 - 4.4e-114 381.3 0.0 5.8e-114 380.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III PqiA PF04403.13 CRK34169.1 - 0.0092 15.8 5.2 1.8 8.4 0.5 2.9 2 0 0 2 2 2 2 Paraquat-inducible protein A Transport_MerF PF11431.8 CRK34169.1 - 0.3 11.0 2.9 28 4.7 0.2 3.3 2 0 0 2 2 2 0 Membrane transport protein MerF eIF-6 PF01912.18 CRK34170.1 - 1.3e-79 266.2 1.1 1.3e-79 266.2 1.1 1.4 2 0 0 2 2 2 1 eIF-6 family DUF572 PF04502.13 CRK34171.1 - 0.24 11.0 6.1 0.48 10.0 6.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) SAP PF02037.27 CRK34173.1 - 8.7e-13 47.7 0.1 1.6e-12 46.9 0.1 1.5 1 0 0 1 1 1 1 SAP domain Tho1_MOS11_C PF18592.1 CRK34173.1 - 5.6e-05 22.9 6.7 0.081 12.7 0.2 3.0 2 1 1 3 3 3 2 Tho1/MOS11 C-terminal domain TFIID_NTD2 PF04494.15 CRK34174.1 - 1.4e-38 132.0 0.0 2.2e-38 131.4 0.0 1.3 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain Peptidase_M28 PF04389.17 CRK34174.1 - 4.7e-36 124.3 0.0 8.6e-36 123.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 WD40 PF00400.32 CRK34174.1 - 5.4e-28 96.7 20.4 1.3e-08 35.3 1.7 6.5 5 1 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK34174.1 - 1e-06 28.9 0.1 0.18 12.1 0.0 3.7 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 CRK34174.1 - 1.2e-05 25.1 0.0 2.7e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 LisH eIF2A PF08662.11 CRK34174.1 - 0.00048 20.1 0.2 0.0037 17.2 0.0 2.4 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Peptidase_M20 PF01546.28 CRK34174.1 - 0.00053 19.7 0.0 0.00098 18.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 SF1-HH PF16275.5 CRK34174.1 - 0.0088 16.4 1.2 0.16 12.3 0.0 2.4 1 1 1 2 2 2 1 Splicing factor 1 helix-hairpin domain Nup160 PF11715.8 CRK34174.1 - 0.19 10.3 0.1 15 4.1 0.1 2.3 2 0 0 2 2 2 0 Nucleoporin Nup120/160 PI-PLC-Y PF00387.19 CRK34176.1 - 3.7e-38 130.4 0.1 6.7e-38 129.6 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain Peptidase_M48 PF01435.18 CRK34176.1 - 8.4e-16 58.3 0.0 1.4e-15 57.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 ABC_tran PF00005.27 CRK34177.1 - 0.00025 21.5 0.0 0.00055 20.5 0.0 1.5 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 CRK34177.1 - 0.00059 19.7 0.0 0.00077 19.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system Phi-29_GP4 PF05464.11 CRK34177.1 - 0.13 12.5 0.1 0.15 12.3 0.1 1.3 1 0 0 1 1 1 0 Phi-29-like late genes activator (early protein GP4) eIF2A PF08662.11 CRK34179.1 - 2.4e-11 43.9 0.1 3.1e-11 43.5 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A L51_S25_CI-B8 PF05047.16 CRK34180.1 - 2.5e-14 52.9 0.0 2.9e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain CaM_binding PF07839.11 CRK34180.1 - 0.055 14.2 0.0 0.064 14.0 0.0 1.0 1 0 0 1 1 1 0 Plant calmodulin-binding domain zf-ZPR1 PF03367.13 CRK34181.1 - 6.6e-22 78.1 0.0 8.2e-22 77.8 0.0 1.1 1 0 0 1 1 1 1 ZPR1 zinc-finger domain Beta_helix PF13229.6 CRK34183.1 - 0.0068 16.3 1.2 0.0074 16.1 1.2 1.2 1 0 0 1 1 1 1 Right handed beta helix region Tudor_4 PF18358.1 CRK34183.1 - 0.081 12.5 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 Histone methyltransferase Tudor domain YARHG PF13308.6 CRK34183.1 - 0.11 12.4 0.1 0.15 11.9 0.1 1.2 1 0 0 1 1 1 0 YARHG domain ketoacyl-synt PF00109.26 CRK34185.1 - 0.00093 18.8 0.0 0.001 18.7 0.0 1.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PnpCD_PnpD_N PF18191.1 CRK34185.1 - 0.066 12.8 0.1 0.1 12.2 0.1 1.3 1 0 0 1 1 1 0 Hydroquinone 1,2-dioxygenase large subunit N-terminal MMS1_N PF10433.9 CRK34186.1 - 1.8e-59 201.7 0.0 2.1e-59 201.5 0.0 1.0 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Acyltransferase PF01553.21 CRK34187.1 - 2.3e-05 24.0 0.0 2.7e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Acyltransferase WD40 PF00400.32 CRK34191.1 - 3.2e-08 34.1 1.4 0.0076 17.1 0.0 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.8 CRK34191.1 - 4.7e-07 28.8 0.5 1.9e-05 23.5 0.9 2.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 CRK34191.1 - 0.00014 22.1 0.2 0.00044 20.5 0.3 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain OB_NTP_bind PF07717.16 CRK34192.1 - 3.5e-20 72.2 0.0 5.5e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Acylphosphatase PF00708.18 CRK34193.1 - 3.1e-23 82.0 0.4 3.6e-23 81.8 0.4 1.0 1 0 0 1 1 1 1 Acylphosphatase Hep_59 PF07052.11 CRK34194.1 - 3.9e-14 53.3 0.0 6e-13 49.5 0.0 2.7 2 2 0 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 Claudin_3 PF06653.11 CRK34197.1 - 0.15 12.0 3.0 0.19 11.6 3.0 1.4 1 1 0 1 1 1 0 Tight junction protein, Claudin-like TRAP_alpha PF03896.16 CRK34198.1 - 0.0099 15.1 0.0 0.017 14.3 0.0 1.4 1 1 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit SNF2_N PF00176.23 CRK34208.1 - 1.4e-18 66.8 1.2 1.5e-18 66.7 1.2 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain baeRF_family12 PF18856.1 CRK34208.1 - 0.00017 22.2 0.2 0.00021 21.9 0.2 1.1 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 12 DUF4449 PF14613.6 CRK34208.1 - 0.0025 18.0 0.3 0.0033 17.5 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4449) Host_attach PF10116.9 CRK34208.1 - 0.03 14.9 0.0 0.036 14.7 0.0 1.1 1 0 0 1 1 1 0 Protein required for attachment to host cells Calreticulin PF00262.18 CRK34213.1 - 1.2e-07 30.9 0.0 2e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Calreticulin family Rxt3 PF08642.10 CRK34213.1 - 0.76 10.6 0.1 0.76 10.6 0.1 2.5 2 1 1 3 3 3 0 Histone deacetylation protein Rxt3 MFS_1 PF07690.16 CRK34214.1 - 1.7e-05 24.0 6.1 1.9e-05 23.7 6.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 CRK34214.1 - 0.00049 19.1 3.9 0.00062 18.7 3.9 1.1 1 0 0 1 1 1 1 MFS_1 like family WD40 PF00400.32 CRK34220.1 - 1.4e-08 35.2 0.3 1.6e-07 31.9 0.3 2.1 2 0 0 2 2 2 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK34220.1 - 0.005 17.1 0.0 0.028 14.7 0.0 1.9 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain DUF3143 PF11341.8 CRK34220.1 - 0.038 14.3 0.0 0.059 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3143) HhH-GPD PF00730.25 CRK34221.1 - 1.1e-06 29.1 0.0 1.7e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein PEMT PF04191.13 CRK34222.1 - 6.4e-06 26.5 0.2 1.1e-05 25.8 0.2 1.4 1 0 0 1 1 1 1 Phospholipid methyltransferase IF-2B PF01008.17 CRK34223.1 - 4.8e-15 55.5 0.4 5.3e-15 55.4 0.4 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family BLM10_N PF16547.5 CRK34225.1 - 4.9e-19 68.4 0.0 1.4e-18 66.9 0.0 1.8 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, N-terminal GMC_oxred_C PF05199.13 CRK34225.1 - 8.3e-13 49.1 0.0 1.3e-12 48.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Trypan_PARP PF05887.11 CRK34228.1 - 0.046 13.7 8.4 0.046 13.7 8.4 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) OPA3 PF07047.12 CRK34231.1 - 4e-20 71.9 0.1 8.6e-20 70.8 0.0 1.5 1 1 1 2 2 2 1 Optic atrophy 3 protein (OPA3) Tropomyosin PF00261.20 CRK34231.1 - 0.0015 18.0 0.7 0.0018 17.7 0.7 1.1 1 0 0 1 1 1 1 Tropomyosin CCDC-167 PF15188.6 CRK34231.1 - 0.015 15.6 0.3 0.02 15.2 0.3 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 XhlA PF10779.9 CRK34231.1 - 0.05 13.8 3.1 0.076 13.2 3.1 1.2 1 0 0 1 1 1 0 Haemolysin XhlA BRI3BP PF14965.6 CRK34231.1 - 0.11 12.0 0.6 1.1 8.8 0.0 2.0 1 1 1 2 2 2 0 Negative regulator of p53/TP53 CH PF00307.31 CRK34233.1 - 6.1e-22 77.9 0.0 7.4e-19 67.9 0.0 2.1 2 0 0 2 2 2 2 Calponin homology (CH) domain Glyco_hydro_61 PF03443.14 CRK34235.1 - 1.8e-35 122.8 0.0 2e-35 122.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 PLA2_B PF01735.18 CRK34235.1 - 0.079 11.4 0.0 0.093 11.1 0.0 1.1 1 0 0 1 1 1 0 Lysophospholipase catalytic domain Glyco_hydro_32N PF00251.20 CRK34238.1 - 0.0069 16.0 0.0 0.0083 15.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain BNR PF02012.20 CRK34238.1 - 0.02 14.8 0.4 0.063 13.3 0.4 1.9 1 0 0 1 1 1 0 BNR/Asp-box repeat Sortilin-Vps10 PF15902.5 CRK34238.1 - 0.1 11.3 0.1 0.13 11.0 0.1 1.1 1 0 0 1 1 1 0 Sortilin, neurotensin receptor 3, BNR_2 PF13088.6 CRK34238.1 - 0.11 11.7 0.1 0.13 11.5 0.1 1.1 1 0 0 1 1 1 0 BNR repeat-like domain 6PF2K PF01591.18 CRK34239.1 - 1e-27 96.9 1.2 1.1e-27 96.8 1.2 1.0 1 0 0 1 1 1 1 6-phosphofructo-2-kinase UQ_con PF00179.26 CRK34241.1 - 8.1e-18 64.4 0.0 9.5e-18 64.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CRK34241.1 - 0.0051 17.1 0.0 0.0075 16.6 0.0 1.2 1 1 0 1 1 1 1 RWD domain Archaeal_AmoA PF12942.7 CRK34242.1 - 0.12 12.1 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Archaeal ammonia monooxygenase subunit A (AmoA) EF-hand_6 PF13405.6 CRK34244.1 - 0.00056 19.6 0.1 0.001 18.8 0.1 1.5 1 0 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.6 CRK34244.1 - 0.00099 18.9 0.0 0.0018 18.1 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain pair Sigma70_ECF PF07638.11 CRK34244.1 - 0.011 15.6 0.1 0.036 14.0 0.0 1.7 1 1 1 2 2 2 0 ECF sigma factor EF-hand_1 PF00036.32 CRK34244.1 - 0.015 14.8 0.0 0.03 13.8 0.0 1.6 1 0 0 1 1 1 0 EF hand zf-RRPl_C4 PF17026.5 CRK34244.1 - 0.076 13.1 0.0 0.097 12.8 0.0 1.2 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type Bac_rhamnosid6H PF17389.2 CRK34246.1 - 0.0011 18.2 0.2 0.0013 18.0 0.2 1.0 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain FapA PF03961.13 CRK34248.1 - 0.24 10.0 6.1 0.27 9.8 6.1 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A HIP1_clath_bdg PF16515.5 CRK34248.1 - 0.52 10.9 17.0 2.3 8.9 2.0 2.1 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 OmpH PF03938.14 CRK34248.1 - 0.61 10.4 10.9 0.86 9.9 10.9 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF5446 PF17522.2 CRK34248.1 - 0.65 10.2 8.9 0.18 12.0 3.5 2.2 1 1 0 2 2 2 0 Family of unknown function (DUF5446) Mitofilin PF09731.9 CRK34249.1 - 9.2e-12 44.6 0.2 9.6e-12 44.5 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial inner membrane protein DUF2959 PF11172.8 CRK34249.1 - 0.054 13.6 0.5 0.081 13.1 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2959) TFIIS_C PF01096.18 CRK34253.1 - 1.2e-13 50.7 0.3 1.2e-13 50.7 0.3 2.6 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 CRK34253.1 - 2e-08 33.9 0.1 4.1e-08 33.0 0.1 1.5 1 0 0 1 1 1 1 RNA polymerases M/15 Kd subunit IBR PF01485.21 CRK34253.1 - 0.0013 18.9 0.6 0.33 11.2 0.2 2.2 2 0 0 2 2 2 2 IBR domain, a half RING-finger domain Zn_Tnp_IS1595 PF12760.7 CRK34253.1 - 0.023 14.7 1.4 0.081 12.9 0.3 2.0 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Nudix_N_2 PF14803.6 CRK34253.1 - 0.54 10.2 5.3 0.21 11.5 1.3 2.1 2 0 0 2 2 2 0 Nudix N-terminal DEAD PF00270.29 CRK34255.1 - 1.8e-08 34.4 0.0 2.6e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase SMC_N PF02463.19 CRK34255.1 - 0.22 10.9 0.3 0.54 9.7 0.1 1.6 1 1 1 2 2 2 0 RecF/RecN/SMC N terminal domain MFS_1 PF07690.16 CRK34256.1 - 2.9e-08 33.0 3.7 3.2e-08 32.9 3.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4282 PF14110.6 CRK34256.1 - 0.00021 22.0 1.9 0.075 13.8 0.3 2.3 2 1 0 2 2 2 2 Domain of unknown function (DUF4282) JAMP PF05571.12 CRK34256.1 - 0.0039 16.9 0.7 0.0047 16.6 0.7 1.1 1 0 0 1 1 1 1 JNK1/MAPK8-associated membrane protein EF-1_beta_acid PF10587.9 CRK34257.1 - 7.6e-15 55.1 9.6 7.6e-15 55.1 9.6 2.2 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region Cwf_Cwc_15 PF04889.12 CRK34257.1 - 0.01 15.6 2.0 0.011 15.5 2.0 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Cpn60_TCP1 PF00118.24 CRK34260.1 - 5.3e-21 74.8 0.6 5.7e-21 74.7 0.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pectate_lyase PF03211.13 CRK34261.1 - 1.6e-50 171.5 10.2 2.1e-50 171.1 10.2 1.1 1 0 0 1 1 1 1 Pectate lyase PPR PF01535.20 CRK34263.1 - 0.01 16.0 0.0 0.018 15.3 0.0 1.4 1 0 0 1 1 1 0 PPR repeat Wzy_C_2 PF11846.8 CRK34263.1 - 0.034 14.1 0.0 0.042 13.8 0.0 1.1 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal Arg_repressor PF01316.21 CRK34263.1 - 0.037 13.8 0.0 0.057 13.2 0.0 1.2 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain PPR_1 PF12854.7 CRK34263.1 - 0.084 12.6 0.2 0.15 11.8 0.2 1.4 1 0 0 1 1 1 0 PPR repeat Pyridoxal_deC PF00282.19 CRK34265.1 - 5.6e-16 58.2 0.0 6.1e-16 58.1 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Rossmann-like PF10727.9 CRK34271.1 - 0.071 13.0 0.0 0.14 12.0 0.0 1.6 1 1 1 2 2 2 0 Rossmann-like domain S1 PF00575.23 CRK34273.1 - 1.7e-10 41.1 1.6 1.7e-10 41.1 0.6 1.5 2 0 0 2 2 2 1 S1 RNA binding domain EIF_2_alpha PF07541.12 CRK34273.1 - 0.00021 21.4 0.0 0.00036 20.6 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit IMS PF00817.20 CRK34276.1 - 1.1e-13 51.4 0.0 1.8e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family RNA_pol_Rpb2_4 PF04566.13 CRK34276.1 - 0.039 14.2 0.1 0.057 13.7 0.1 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 4 Aminotran_5 PF00266.19 CRK34277.1 - 3.3e-05 23.0 0.0 3.4e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V VAPB_antitox PF02697.14 CRK34277.1 - 0.0036 18.0 0.0 0.0054 17.5 0.0 1.4 1 0 0 1 1 1 1 Putative antitoxin PorB PF11565.8 CRK34277.1 - 0.069 13.6 0.1 1.8 9.1 0.0 2.2 1 1 1 2 2 2 0 Alpha helical Porin B Aldedh PF00171.22 CRK34297.1 - 1.4e-130 435.9 0.0 1.6e-130 435.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 CRK34297.1 - 5.4e-05 22.4 0.0 0.00011 21.3 0.0 1.5 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) Prefoldin_2 PF01920.20 CRK34297.1 - 0.51 10.3 3.4 16 5.5 1.2 2.6 3 0 0 3 3 3 0 Prefoldin subunit Kelch_3 PF13415.6 CRK34301.1 - 1.7e-26 91.9 1.8 1.3e-07 31.7 0.0 6.6 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_4 PF13418.6 CRK34301.1 - 8.7e-24 83.3 7.6 5.3e-12 45.6 0.1 5.9 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.6 CRK34301.1 - 2.6e-11 43.4 0.9 0.089 13.1 0.1 5.3 5 1 1 6 6 6 3 Kelch motif Kelch_1 PF01344.25 CRK34301.1 - 4.7e-08 32.5 0.1 0.078 12.6 0.0 5.5 6 0 0 6 6 6 3 Kelch motif Kelch_5 PF13854.6 CRK34301.1 - 8.9e-06 25.6 0.1 0.14 12.1 0.0 4.6 5 0 0 5 5 5 1 Kelch motif Kelch_2 PF07646.15 CRK34301.1 - 0.00021 21.1 3.8 1.9 8.6 0.0 5.0 5 1 0 5 5 5 1 Kelch motif Meleagrin PF08189.11 CRK34301.1 - 0.23 11.2 0.5 0.61 9.8 0.0 1.9 2 0 0 2 2 2 0 Meleagrin/Cygnin family WD40 PF00400.32 CRK34302.1 - 4.4e-15 55.8 4.6 0.0028 18.5 0.0 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK34302.1 - 9.6e-06 25.8 0.1 0.76 10.1 0.0 4.2 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PapG_C PF03628.13 CRK34302.1 - 0.13 12.2 0.1 0.39 10.6 0.0 1.8 2 0 0 2 2 2 0 PapG chaperone-binding domain MoeA_N PF03453.17 CRK34307.1 - 7.2e-30 103.8 1.0 1e-29 103.3 1.0 1.2 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.24 CRK34307.1 - 5e-27 94.3 0.0 1.7e-26 92.6 0.0 1.8 2 0 0 2 2 2 1 Probable molybdopterin binding domain MoeA_C PF03454.15 CRK34307.1 - 0.048 13.8 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 MoeA C-terminal region (domain IV) Molybdopterin PF00384.22 CRK34308.1 - 1.7e-65 221.7 0.0 2.4e-65 221.2 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 CRK34308.1 - 1.6e-27 95.7 0.0 3.9e-27 94.5 0.0 1.7 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Molybdop_Fe4S4 PF04879.16 CRK34308.1 - 1e-12 47.8 1.0 2e-12 46.9 0.4 1.9 2 0 0 2 2 2 1 Molybdopterin oxidoreductase Fe4S4 domain MFS_1 PF07690.16 CRK34310.1 - 1.5e-38 132.7 45.1 1.5e-38 132.7 45.1 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 CRK34310.1 - 2.3e-13 49.5 16.8 3.2e-13 49.0 16.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Rib_5-P_isom_A PF06026.14 CRK34313.1 - 1e-44 152.2 0.0 1.7e-44 151.4 0.0 1.4 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 CRK34313.1 - 0.00064 19.7 0.0 0.71 9.8 0.0 2.8 3 0 0 3 3 3 2 DeoR C terminal sensor domain RR_TM4-6 PF06459.12 CRK34315.1 - 7.7 6.3 9.7 0.63 9.8 4.0 1.9 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 tRNA-synt_1b PF00579.25 CRK34316.1 - 8.8e-19 67.9 0.0 1.7e-18 67.0 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) PMI_typeI PF01238.21 CRK34323.1 - 2.1e-57 195.0 0.0 2.4e-56 191.6 0.0 2.1 1 1 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.19 CRK34323.1 - 0.00062 19.7 0.0 0.0092 15.9 0.0 2.4 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_2 PF07883.11 CRK34323.1 - 0.005 16.5 0.1 1.1 9.1 0.1 2.5 2 0 0 2 2 2 2 Cupin domain TMEM119 PF15724.5 CRK34323.1 - 0.29 11.2 4.5 0.52 10.3 4.5 1.3 1 0 0 1 1 1 0 TMEM119 family GLTP PF08718.11 CRK34326.1 - 7.9e-43 146.3 0.2 2.1e-42 144.9 0.1 1.6 2 0 0 2 2 2 1 Glycolipid transfer protein (GLTP) PLDc PF00614.22 CRK34329.1 - 1.3e-14 53.6 1.5 1.8e-07 31.1 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 CRK34329.1 - 1.7e-13 50.6 0.0 1.9e-05 24.6 0.0 3.9 3 1 0 3 3 3 3 PLD-like domain Pkinase PF00069.25 CRK34331.1 - 9.6e-70 234.9 0.0 1.4e-69 234.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK34331.1 - 2e-33 115.8 0.0 3.3e-33 115.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 CRK34331.1 - 2.9e-19 69.6 0.8 4.1e-11 43.4 0.2 2.9 2 1 0 2 2 2 2 Adenylate sensor of SNF1-like protein kinase UBA_2 PF08587.11 CRK34331.1 - 3.1e-16 59.2 0.4 6.8e-16 58.1 0.4 1.6 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.6 CRK34331.1 - 3.7e-05 23.2 0.0 6.4e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CRK34331.1 - 0.00059 18.9 1.3 0.00073 18.6 0.3 1.6 2 0 0 2 2 2 1 Haspin like kinase domain MaoC_dehydrat_N PF13452.6 CRK34331.1 - 0.01 16.0 0.3 1.9 8.6 0.0 2.5 2 0 0 2 2 2 0 N-terminal half of MaoC dehydratase RIO1 PF01163.22 CRK34331.1 - 0.018 14.6 0.2 0.047 13.3 0.1 1.7 1 1 0 1 1 1 0 RIO1 family YukC PF10140.9 CRK34331.1 - 0.02 13.7 0.0 0.032 13.1 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Kdo PF06293.14 CRK34331.1 - 0.1 11.9 0.4 0.22 10.9 0.4 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CRK34331.1 - 0.11 12.4 0.4 0.3 11.0 0.2 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family DNA_pol_E_B PF04042.16 CRK34335.1 - 3.5e-65 219.3 0.0 4.7e-65 218.9 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B FUSC_2 PF13515.6 CRK34337.1 - 0.00026 21.1 0.0 0.00044 20.4 0.0 1.4 1 0 0 1 1 1 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 CRK34337.1 - 0.0039 17.0 0.0 0.0062 16.4 0.0 1.4 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 FUSC_2 PF13515.6 CRK34339.1 - 2.3e-12 47.2 9.0 2.3e-12 47.2 9.0 2.5 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.8 CRK34339.1 - 1.1e-07 31.1 3.5 3.3e-05 22.9 4.0 2.8 3 0 0 3 3 3 2 Aluminium activated malate transporter FUSC-like PF12805.7 CRK34339.1 - 0.036 13.1 0.6 0.072 12.2 0.6 1.5 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS HAD_2 PF13419.6 CRK34342.1 - 6.4e-14 52.4 0.0 2.1e-13 50.7 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CRK34342.1 - 4.2e-09 37.0 0.0 1.6e-05 25.3 0.0 2.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CRK34342.1 - 8.4e-06 25.8 0.5 1.5e-05 24.9 0.1 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.7 CRK34342.1 - 0.0017 18.8 0.1 0.0098 16.3 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 CRK34342.1 - 0.014 15.0 0.1 1.5 8.4 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase Pkinase PF00069.25 CRK34344.1 - 7.6e-57 192.7 0.0 1.8e-56 191.5 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK34344.1 - 3.4e-36 124.8 0.0 6.8e-36 123.9 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CRK34344.1 - 8.7e-05 21.5 0.0 0.00013 20.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CRK34344.1 - 0.00056 19.3 0.0 0.0009 18.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CRK34344.1 - 0.039 12.9 0.0 0.053 12.5 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 CRK34344.1 - 0.085 11.9 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 SPT6_acidic PF14632.6 CRK34346.1 - 9.1e-15 55.0 33.0 9.1e-15 55.0 33.0 2.0 1 1 1 2 2 2 2 Acidic N-terminal SPT6 A_deaminase PF00962.22 CRK34349.1 - 5.6e-20 71.9 0.0 8.5e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase Sugar_tr PF00083.24 CRK34351.1 - 2.1e-102 343.3 18.8 3.3e-102 342.7 18.8 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK34351.1 - 1.5e-25 89.9 53.3 9.4e-18 64.2 23.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily SH2_2 PF14633.6 CRK34353.1 - 1.1e-81 273.4 0.0 2.1e-81 272.5 0.0 1.5 1 0 0 1 1 1 1 SH2 domain HTH_44 PF14641.6 CRK34353.1 - 1.9e-39 134.6 0.2 4.9e-39 133.3 0.2 1.7 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 HHH_7 PF14635.6 CRK34353.1 - 6.3e-22 77.9 0.0 1.7e-21 76.5 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_9 PF17674.1 CRK34353.1 - 1.2e-05 26.1 1.9 1.2e-05 26.1 1.9 4.4 4 1 0 4 4 4 1 HHH domain SH2 PF00017.24 CRK34353.1 - 1.3e-05 25.2 0.0 5.3e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 SH2 domain Tex_N PF09371.10 CRK34353.1 - 0.00029 20.6 0.1 0.22 11.2 0.0 2.8 2 0 0 2 2 2 2 Tex-like protein N-terminal domain S1 PF00575.23 CRK34353.1 - 0.00088 19.6 0.9 0.0017 18.6 0.9 1.5 1 0 0 1 1 1 1 S1 RNA binding domain HHH_3 PF12836.7 CRK34353.1 - 0.0011 19.2 0.0 0.0043 17.3 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix motif RRP7 PF12923.7 CRK34355.1 - 1.1e-28 99.7 14.0 1.1e-28 99.7 14.0 2.1 3 0 0 3 3 3 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain MOSC PF03473.17 CRK34355.1 - 2.2e-24 85.9 0.0 2.4e-23 82.6 0.0 2.3 2 0 0 2 2 2 1 MOSC domain RRM_Rrp7 PF17799.1 CRK34355.1 - 7.4e-14 51.9 0.0 1.4e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 Rrp7 RRM-like N-terminal domain NAD_binding_1 PF00175.21 CRK34355.1 - 3.7e-05 24.3 1.2 0.0033 18.0 0.0 3.6 3 1 0 3 3 3 1 Oxidoreductase NAD-binding domain 3-alpha PF03475.14 CRK34355.1 - 8.4e-05 22.4 1.9 9.6e-05 22.2 0.2 2.1 2 0 0 2 2 2 1 3-alpha domain F-box-like PF12937.7 CRK34357.1 - 0.12 12.3 0.1 0.3 11.0 0.1 1.7 1 0 0 1 1 1 0 F-box-like BAR PF03114.18 CRK34359.1 - 9.7e-47 159.6 11.9 1.2e-29 103.7 5.1 2.1 1 1 1 2 2 2 2 BAR domain SH3_1 PF00018.28 CRK34359.1 - 8.3e-16 57.3 0.1 1.4e-15 56.6 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CRK34359.1 - 3.1e-13 49.3 0.1 5.3e-13 48.6 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CRK34359.1 - 1.6e-09 37.3 0.0 3.4e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain TMPIT PF07851.13 CRK34359.1 - 0.072 12.3 4.2 0.1 11.9 4.2 1.2 1 0 0 1 1 1 0 TMPIT-like protein Sec20 PF03908.13 CRK34359.1 - 0.19 11.6 2.4 2.3 8.2 0.4 2.4 1 1 1 2 2 2 0 Sec20 AAA_15 PF13175.6 CRK34359.1 - 0.21 11.3 6.6 0.27 10.9 6.6 1.1 1 0 0 1 1 1 0 AAA ATPase domain YlqD PF11068.8 CRK34359.1 - 1.8 9.0 4.3 1 9.7 2.4 1.6 2 0 0 2 2 2 0 YlqD protein Aminotran_5 PF00266.19 CRK34361.1 - 1e-94 317.5 0.0 1.3e-94 317.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 CRK34361.1 - 8.6e-08 31.9 0.0 5.1e-07 29.3 0.1 2.0 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 CRK34361.1 - 2.3e-07 30.4 0.2 3.6e-07 29.7 0.2 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 CRK34361.1 - 0.00077 18.1 0.0 0.0012 17.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Pyridoxal_deC PF00282.19 CRK34361.1 - 0.016 13.9 0.0 0.025 13.3 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain SPT16 PF08644.11 CRK34363.1 - 7.1e-54 182.1 0.0 7.1e-54 182.1 0.0 2.2 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) Rtt106 PF08512.12 CRK34363.1 - 1.3e-15 57.5 0.8 4.1e-15 56.0 0.1 2.1 2 0 0 2 2 2 1 Histone chaperone Rttp106-like CDC50 PF03381.15 CRK34365.1 - 1.4e-100 336.5 0.1 1.7e-100 336.2 0.1 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family PD40 PF07676.12 CRK34365.1 - 0.044 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat bZIP_1 PF00170.21 CRK34368.1 - 0.00027 21.0 6.4 0.00027 21.0 6.4 1.6 2 0 0 2 2 2 1 bZIP transcription factor TipAS PF07739.13 CRK34368.1 - 0.035 14.6 2.3 0.065 13.8 1.4 1.8 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain HABP4_PAI-RBP1 PF04774.15 CRK34368.1 - 0.043 14.7 15.5 0.27 12.1 0.3 3.3 3 1 0 3 3 3 0 Hyaluronan / mRNA binding family PKcGMP_CC PF16808.5 CRK34368.1 - 0.25 11.2 3.2 0.45 10.4 3.2 1.3 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Gastrin PF00918.17 CRK34368.1 - 4.3 8.3 8.6 1.5 9.8 5.3 1.9 2 0 0 2 2 2 0 Gastrin/cholecystokinin family bZIP_2 PF07716.15 CRK34368.1 - 7.5 6.7 15.4 0.087 12.9 7.7 1.7 2 0 0 2 2 2 0 Basic region leucine zipper Cyt-b5 PF00173.28 CRK34371.1 - 3.2e-09 36.8 0.1 5.1e-09 36.2 0.1 1.4 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain zf-C2H2 PF00096.26 CRK34379.1 - 0.00014 22.2 5.8 13 6.4 0.2 5.0 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 CRK34379.1 - 0.00022 21.4 0.4 0.48 10.8 0.0 4.2 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 CRK34379.1 - 0.00068 20.3 13.5 0.36 11.8 0.1 5.1 5 0 0 5 5 5 2 C2H2-type zinc finger zf-met PF12874.7 CRK34379.1 - 0.0027 18.1 0.6 0.74 10.3 0.1 4.0 3 0 0 3 3 3 1 Zinc-finger of C2H2 type Kelch_3 PF13415.6 CRK34381.1 - 6.6e-22 77.3 7.7 2.5e-07 30.8 0.3 7.1 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_1 PF01344.25 CRK34381.1 - 1.8e-16 59.4 0.5 3.9e-09 36.0 0.0 5.3 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.6 CRK34381.1 - 2e-15 56.3 9.4 5.5e-06 26.2 0.0 6.9 7 0 0 7 7 7 3 Kelch motif Kelch_6 PF13964.6 CRK34381.1 - 2.5e-15 56.1 5.6 2.3e-07 30.8 0.0 5.7 5 2 2 7 7 7 2 Kelch motif Kelch_2 PF07646.15 CRK34381.1 - 6.5e-13 48.1 3.8 2.1e-08 33.8 0.0 4.8 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.6 CRK34381.1 - 1.4e-11 44.2 13.1 0.0016 18.4 0.1 6.9 7 1 0 7 7 7 4 Galactose oxidase, central domain Tub_N PF16322.5 CRK34381.1 - 0.12 12.8 2.3 0.19 12.1 2.3 1.2 1 0 0 1 1 1 0 Tubby N-terminal 2Fe-2S_thioredx PF01257.19 CRK34382.1 - 4e-58 195.4 0.0 5e-58 195.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin PCI PF01399.27 CRK34385.1 - 0.092 13.3 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 PCI domain Rep_fac-A_C PF08646.10 CRK34387.1 - 2.3e-55 186.4 5.2 3.2e-54 182.7 2.2 2.3 2 0 0 2 2 2 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 CRK34387.1 - 2.5e-39 133.1 0.8 8.4e-39 131.4 0.6 2.0 2 0 0 2 2 2 1 Replication protein A OB domain Rep-A_N PF04057.12 CRK34387.1 - 2.8e-21 75.4 0.0 5.4e-21 74.5 0.0 1.5 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 CRK34387.1 - 1.2e-14 54.1 0.1 5.9e-11 42.2 0.0 3.6 3 1 0 3 3 3 2 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 CRK34387.1 - 1.8e-05 24.6 0.5 0.015 15.0 0.2 3.0 3 0 0 3 3 3 2 Cell division control protein 24, OB domain 3 DUF5521 PF17659.1 CRK34387.1 - 0.0098 13.8 0.1 0.056 11.3 0.1 1.8 1 1 0 1 1 1 1 Family of unknown function (DUF5521) DUF223 PF02721.14 CRK34387.1 - 0.078 13.3 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF223 zf-like PF04071.12 CRK34387.1 - 0.095 12.6 0.6 0.24 11.3 0.6 1.6 1 0 0 1 1 1 0 Cysteine-rich small domain DLH PF01738.18 CRK34389.1 - 1.1e-17 64.3 0.0 3.5e-08 33.3 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family ADH_zinc_N PF00107.26 CRK34391.1 - 1.9e-22 79.6 0.5 3.8e-22 78.7 0.5 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CRK34391.1 - 5.5e-22 79.3 0.0 8.6e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CRK34391.1 - 3.7e-07 30.0 0.0 5e-06 26.4 0.0 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Glyco_hydro_20b PF02838.15 CRK34393.1 - 0.015 16.1 1.1 1.4e+02 3.2 0.0 4.2 4 0 0 4 4 4 0 Glycosyl hydrolase family 20, domain 2 SnoaL_3 PF13474.6 CRK34393.1 - 0.08 13.2 1.8 26 5.1 0.0 3.6 3 1 1 4 4 4 0 SnoaL-like domain CW_7 PF08230.11 CRK34393.1 - 0.51 10.1 4.7 74 3.2 0.1 3.6 4 0 0 4 4 4 0 CW_7 repeat ChaC PF04752.12 CRK34393.1 - 1.1 9.2 5.6 15 5.6 0.3 3.5 3 1 1 4 4 4 0 ChaC-like protein PE-PPE PF08237.11 CRK34394.1 - 0.0089 15.6 0.4 0.01 15.4 0.4 1.0 1 0 0 1 1 1 1 PE-PPE domain AMP-binding PF00501.28 CRK34396.1 - 1.1e-71 241.6 0.0 1.4e-71 241.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 CRK34396.1 - 1e-18 67.0 0.9 2.6e-18 65.7 0.4 2.1 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 CRK34396.1 - 3.8e-08 34.2 0.0 8e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain BRCT_2 PF16589.5 CRK34399.1 - 1.5e-06 28.5 0.0 2.3e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 CRK34399.1 - 3.3e-05 23.8 0.1 8.5e-05 22.4 0.0 1.7 2 0 0 2 2 2 1 twin BRCT domain LIG3_BRCT PF16759.5 CRK34399.1 - 0.011 16.0 0.0 0.019 15.3 0.0 1.4 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain BRCT PF00533.26 CRK34399.1 - 0.016 15.6 0.0 0.027 14.8 0.0 1.3 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain AMP-binding PF00501.28 CRK34400.1 - 2.1e-71 240.8 0.0 2.6e-71 240.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CRK34400.1 - 1.8e-19 70.5 1.2 1.1e-18 67.9 0.2 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 CRK34400.1 - 1.6e-18 66.3 0.9 3.4e-18 65.3 0.4 1.9 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus PTCB-BRCT PF12738.7 CRK34402.1 - 4.2e-05 23.4 0.0 7.2e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 CRK34402.1 - 0.04 14.3 0.0 0.064 13.7 0.0 1.3 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain KilA-N PF04383.13 CRK34407.1 - 0.00071 19.4 0.0 0.013 15.3 0.0 2.3 1 1 0 1 1 1 1 KilA-N domain Med1 PF10744.9 CRK34409.1 - 2.4e-119 399.1 0.0 3e-119 398.8 0.0 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 Pkinase PF00069.25 CRK34410.1 - 2.3e-40 138.6 0.0 2.6e-38 131.9 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CRK34410.1 - 1.1e-21 77.3 0.0 2.9e-21 75.9 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Exostosin PF03016.15 CRK34410.1 - 0.033 13.4 0.0 0.069 12.4 0.0 1.5 1 0 0 1 1 1 0 Exostosin family GCP_C_terminal PF04130.13 CRK34412.1 - 2.3e-98 329.5 0.0 3.8e-98 328.8 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 CRK34412.1 - 9.2e-85 284.9 0.0 1.5e-84 284.2 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal SAGA-Tad1 PF12767.7 CRK34415.1 - 3.6e-64 216.7 0.0 4.5e-64 216.4 0.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit AMP-binding PF00501.28 CRK34416.1 - 2.7e-109 365.6 2.7 2.1e-60 204.5 0.2 2.2 1 1 1 2 2 2 2 AMP-binding enzyme BCAS2 PF05700.11 CRK34416.1 - 1.7e-52 178.1 1.0 2.6e-52 177.5 1.0 1.2 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) AMP-binding_C PF13193.6 CRK34416.1 - 1.6e-11 45.0 0.2 4.1e-11 43.7 0.2 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF5465 PF17553.2 CRK34416.1 - 0.0061 16.9 0.4 9 7.1 0.0 2.8 2 0 0 2 2 2 2 Family of unknown function (DUF5465) cNMP_binding PF00027.29 CRK34419.1 - 1.2e-40 137.4 0.0 9.4e-22 76.9 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 CRK34419.1 - 6.7e-05 22.5 0.1 0.00013 21.6 0.1 1.4 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit zf-PHD-like PF15446.6 CRK34420.1 - 1.3e-70 236.4 14.4 2.5e-70 235.5 14.4 1.5 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.23 CRK34420.1 - 7.1e-37 126.9 0.0 8.8e-37 126.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CRK34420.1 - 8.1e-17 61.6 0.0 1.8e-16 60.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 CRK34420.1 - 4.1e-07 29.5 0.9 1.3e-06 27.8 0.9 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Chromo PF00385.24 CRK34420.1 - 1.2e-05 25.1 0.1 0.00043 20.1 0.2 2.7 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.29 CRK34420.1 - 0.0014 18.5 6.3 0.0014 18.5 6.3 3.2 2 1 1 3 3 3 2 PHD-finger Zf_RING PF16744.5 CRK34420.1 - 0.021 14.9 11.1 0.77 9.9 3.7 2.6 2 0 0 2 2 2 0 KIAA1045 RING finger AT_hook PF02178.19 CRK34420.1 - 0.14 12.1 3.0 0.53 10.3 3.0 2.1 1 0 0 1 1 1 0 AT hook motif VirC1 PF07015.11 CRK34420.1 - 0.18 11.1 0.0 0.39 10.0 0.0 1.5 1 0 0 1 1 1 0 VirC1 protein RPA_interact_C PF14768.6 CRK34420.1 - 1.2 9.8 5.7 5.2 7.7 5.7 2.2 1 0 0 1 1 1 0 Replication protein A interacting C-terminal DUF2318 PF10080.9 CRK34420.1 - 2 8.6 6.0 0.17 12.0 0.5 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) SpoU_methylase PF00588.19 CRK34422.1 - 1.7e-17 63.9 0.1 2.7e-09 37.3 0.0 2.4 1 1 1 2 2 2 2 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 CRK34422.1 - 9.3e-11 41.9 0.0 3.8e-10 39.9 0.0 2.0 2 0 0 2 2 2 1 RNA 2'-O ribose methyltransferase substrate binding MBF1 PF08523.10 CRK34426.1 - 1.5e-21 76.6 0.5 2.7e-21 75.8 0.5 1.4 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 CRK34426.1 - 1.6e-09 37.6 0.0 2.7e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix MRP-L27 PF09809.9 CRK34426.1 - 0.039 13.8 0.1 0.049 13.5 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L27 HTH_31 PF13560.6 CRK34426.1 - 0.11 12.9 0.0 0.18 12.2 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain GFA PF04828.14 CRK34428.1 - 6.2e-24 84.2 0.0 9.5e-24 83.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.7 CRK34428.1 - 0.12 12.5 3.2 0.79 9.8 0.2 2.4 2 1 0 2 2 2 0 Double zinc ribbon tRNA-synt_1 PF00133.22 CRK34433.1 - 7.3e-207 688.3 0.0 9.3e-207 688.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CRK34433.1 - 2.3e-23 82.8 0.0 4.7e-23 81.8 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 CRK34433.1 - 2.7e-16 59.3 1.3 3.6e-07 29.3 0.1 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 CRK34433.1 - 5.2e-05 22.7 0.0 0.0076 15.6 0.0 3.0 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain DUF4768 PF15989.5 CRK34433.1 - 0.11 12.5 0.4 0.26 11.2 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4768) GST_N_3 PF13417.6 CRK34435.1 - 2.3e-10 40.7 0.1 4.1e-10 39.9 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CRK34435.1 - 0.00014 22.1 0.0 0.00025 21.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CRK34435.1 - 0.0038 17.2 3.1 0.0079 16.2 3.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CRK34435.1 - 0.041 14.1 0.0 0.086 13.1 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain MIS13 PF08202.11 CRK34437.1 - 4.1e-60 203.6 0.5 7.8e-60 202.7 0.5 1.4 1 0 0 1 1 1 1 Mis12-Mtw1 protein family YvrJ PF12841.7 CRK34437.1 - 0.48 10.0 1.8 13 5.4 0.0 2.3 2 0 0 2 2 2 0 YvrJ protein family Alanine_zipper PF11839.8 CRK34437.1 - 0.5 10.8 3.4 19 5.7 0.0 3.3 3 0 0 3 3 3 0 Alanine-zipper, major outer membrane lipoprotein ZapB PF06005.12 CRK34437.1 - 0.75 10.3 8.2 8.2 6.9 3.5 2.7 2 0 0 2 2 2 0 Cell division protein ZapB EMP24_GP25L PF01105.24 CRK34439.1 - 5.3e-42 143.8 0.0 6.5e-42 143.5 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF4686 PF15742.5 CRK34439.1 - 0.12 11.5 0.3 0.15 11.2 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4686) Helicase_RecD PF05127.14 CRK34439.1 - 0.12 12.2 0.0 0.28 11.0 0.0 1.7 2 0 0 2 2 2 0 Helicase zf-U1 PF06220.12 CRK34441.1 - 6.4e-22 77.0 3.4 9.4e-22 76.5 3.4 1.3 1 0 0 1 1 1 1 U1 zinc finger Epimerase PF01370.21 CRK34451.1 - 3.3e-32 111.9 0.0 5.5e-32 111.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CRK34451.1 - 6.8e-29 101.3 0.0 1.2e-28 100.5 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 CRK34451.1 - 4.6e-14 52.1 0.0 6.4e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Helicase_C PF00271.31 CRK34451.1 - 1.2e-13 51.4 0.0 2.1e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RmlD_sub_bind PF04321.17 CRK34451.1 - 1.1e-10 41.2 0.0 1.7e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 CRK34451.1 - 2.2e-10 40.1 0.1 3.1e-08 33.1 0.1 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 CRK34451.1 - 5.8e-06 25.7 0.0 9.9e-06 24.9 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 CRK34451.1 - 0.0012 18.8 0.0 0.0017 18.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Helicase_C_2 PF13307.6 CRK34451.1 - 0.0039 17.4 0.0 0.0066 16.6 0.0 1.3 1 0 0 1 1 1 1 Helicase C-terminal domain KR PF08659.10 CRK34451.1 - 0.0085 16.0 0.0 0.019 14.9 0.0 1.6 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 CRK34451.1 - 0.032 13.7 0.0 0.07 12.6 0.0 1.5 1 1 0 1 1 1 0 short chain dehydrogenase WD40 PF00400.32 CRK34454.1 - 1e-08 35.7 0.1 0.0027 18.5 0.0 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat Frtz PF11768.8 CRK34454.1 - 0.064 11.6 0.0 0.065 11.5 0.0 1.1 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz VHL PF01847.16 CRK34454.1 - 0.071 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 VHL beta domain p450 PF00067.22 CRK34456.1 - 0.001 17.9 0.0 0.0011 17.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 JmjN PF02375.17 CRK34456.1 - 0.11 12.5 0.2 0.19 11.7 0.2 1.4 1 0 0 1 1 1 0 jmjN domain RE_HaeIII PF09556.10 CRK34456.1 - 0.13 11.3 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 HaeIII restriction endonuclease Glycogen_syn PF05693.13 CRK34463.1 - 2.7e-41 141.9 0.0 2.9e-41 141.8 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase PEPCK_ATP PF01293.20 CRK34475.1 - 7.9e-48 163.3 0.2 8.6e-48 163.2 0.2 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_29 PF13555.6 CRK34475.1 - 0.019 14.7 0.1 0.042 13.6 0.1 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_33 PF13671.6 CRK34475.1 - 0.022 14.9 0.0 0.032 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 CRK34475.1 - 0.12 12.3 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase AAA_25 PF13481.6 CRK34475.1 - 0.14 11.8 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CRK34475.1 - 0.14 12.5 0.0 0.17 12.3 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 CRK34475.1 - 0.16 12.5 0.0 0.17 12.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain ACT_7 PF13840.6 CRK34476.1 - 2.1e-18 65.9 0.0 2.6e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 ACT domain DUF3716 PF12511.8 CRK34477.1 - 1e-16 60.7 10.4 1.3e-16 60.3 10.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) DUF397 PF04149.12 CRK34479.1 - 0.04 14.0 0.0 0.079 13.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF397) IBN_N PF03810.19 CRK34480.1 - 1.6e-14 53.5 0.1 2.6e-14 52.9 0.1 1.4 1 0 0 1 1 1 1 Importin-beta N-terminal domain Corona_6B_7B PF03262.13 CRK34480.1 - 0.061 12.8 0.0 0.076 12.5 0.0 1.1 1 0 0 1 1 1 0 Coronavirus 6B/7B protein MspA PF09203.11 CRK34480.1 - 0.22 11.3 0.0 0.27 11.1 0.0 1.1 1 0 0 1 1 1 0 MspA DUF3337 PF11816.8 CRK34481.1 - 1.5e-37 129.1 0.0 1.7e-37 128.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) Fungal_trans PF04082.18 CRK34482.1 - 9.6e-12 44.5 0.0 1.1e-11 44.3 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_8 PF05148.15 CRK34487.1 - 4.5e-30 105.1 0.0 2.8e-26 92.7 0.0 2.3 2 0 0 2 2 2 2 Hypothetical methyltransferase Methyltransf_11 PF08241.12 CRK34487.1 - 0.00019 22.0 0.0 0.00061 20.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK34487.1 - 0.015 16.0 0.0 0.049 14.3 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain NTP_transf_6 PF06042.11 CRK34487.1 - 0.07 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Nucleotidyltransferase EF-hand_9 PF14658.6 CRK34488.1 - 3.3e-12 46.6 0.0 9.8e-07 29.0 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 CRK34488.1 - 2.7e-09 37.3 0.2 0.00022 21.6 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CRK34488.1 - 3.1e-09 36.0 0.6 0.0043 16.9 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 CRK34488.1 - 2.2e-08 33.1 0.3 0.012 15.1 0.0 3.1 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 CRK34488.1 - 2.8e-05 23.9 0.1 0.077 12.9 0.1 3.2 3 0 0 3 3 3 2 EF-hand domain pair Methyltransf_11 PF08241.12 CRK34489.1 - 5e-21 75.2 0.0 5.9e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CRK34489.1 - 5.8e-19 68.5 0.0 6.9e-19 68.3 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK34489.1 - 1e-16 61.4 0.0 1.4e-16 61.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK34489.1 - 9.6e-15 55.1 0.0 1.1e-14 54.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK34489.1 - 3.3e-11 43.2 0.0 3.9e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 CRK34489.1 - 3.5e-05 22.9 0.0 4.1e-05 22.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PrmA PF06325.13 CRK34489.1 - 0.00028 20.4 0.0 0.00035 20.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 CRK34489.1 - 0.0022 17.6 0.0 0.0033 17.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 CRK34489.1 - 0.0031 16.9 0.0 0.0077 15.6 0.0 1.6 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase NodS PF05401.11 CRK34489.1 - 0.029 14.0 0.0 0.034 13.8 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_2 PF00891.18 CRK34489.1 - 0.12 11.6 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 O-methyltransferase domain Bmt2 PF11968.8 CRK34489.1 - 0.31 10.8 0.0 0.47 10.3 0.0 1.3 1 0 0 1 1 1 0 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 MMR_HSR1 PF01926.23 CRK34491.1 - 1.4e-06 28.4 0.7 2.5e-06 27.6 0.4 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CRK34491.1 - 8e-05 22.6 0.1 0.0071 16.3 0.1 2.1 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 CRK34491.1 - 0.00088 18.8 0.0 0.01 15.4 0.1 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 CRK34491.1 - 0.0012 17.9 0.0 0.0063 15.5 0.0 1.8 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 CRK34491.1 - 0.0029 17.7 0.1 0.0054 16.8 0.1 1.5 1 0 0 1 1 1 1 Dynamin family AAA_16 PF13191.6 CRK34491.1 - 0.0053 17.1 0.1 0.18 12.2 0.1 2.1 2 0 0 2 2 2 1 AAA ATPase domain GTP_EFTU PF00009.27 CRK34491.1 - 0.0071 15.9 0.0 0.54 9.8 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Torsin PF06309.11 CRK34491.1 - 0.034 14.2 0.0 0.047 13.8 0.0 1.2 1 0 0 1 1 1 0 Torsin TniB PF05621.11 CRK34491.1 - 0.055 12.9 0.0 0.08 12.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein Acetyltransf_CG PF14542.6 CRK34491.1 - 0.12 12.6 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase cobW PF02492.19 CRK34491.1 - 0.19 11.3 0.1 2.3 7.8 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Na_H_Exchanger PF00999.21 CRK34492.1 - 4.1e-15 55.5 4.3 4.3e-15 55.4 4.3 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Rad4 PF03835.15 CRK34493.1 - 7.7e-14 51.6 0.9 9.1e-14 51.4 0.9 1.1 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.19 CRK34493.1 - 0.0015 18.9 3.6 0.003 18.0 3.6 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily Sulfate_transp PF00916.20 CRK34496.1 - 8.2e-32 110.4 2.8 9.8e-32 110.1 2.8 1.0 1 0 0 1 1 1 1 Sulfate permease family RabGAP-TBC PF00566.18 CRK34497.1 - 3.3e-13 49.8 0.0 3.5e-13 49.7 0.0 1.0 1 0 0 1 1 1 1 Rab-GTPase-TBC domain TPR_4 PF07721.14 CRK34498.1 - 0.072 13.7 0.9 0.072 13.7 0.9 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat ABC_membrane PF00664.23 CRK34502.1 - 7.8e-15 55.2 0.9 8.4e-15 55.2 0.9 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region Plasmid_stab_B PF10784.9 CRK34502.1 - 0.038 13.8 0.0 0.051 13.4 0.0 1.2 1 0 0 1 1 1 0 Plasmid stability protein Dus PF01207.17 CRK34503.1 - 0.00034 19.8 0.0 0.00039 19.6 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) EFhand_Ca_insen PF08726.10 CRK34505.1 - 6.6e-23 80.6 0.0 8.6e-23 80.2 0.0 1.2 1 0 0 1 1 1 1 Ca2+ insensitive EF hand DUF913 PF06025.12 CRK34507.1 - 1.4e-06 27.5 0.1 2.5e-06 26.7 0.0 1.4 2 0 0 2 2 2 1 Domain of Unknown Function (DUF913) UMPH-1 PF05822.12 CRK34507.1 - 0.067 12.7 0.0 0.07 12.6 0.0 1.1 1 0 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) COesterase PF00135.28 CRK34509.1 - 0.025 13.5 0.1 0.027 13.3 0.1 1.0 1 0 0 1 1 1 0 Carboxylesterase family ALIX_LYPXL_bnd PF13949.6 CRK34510.1 - 2.4e-11 43.5 0.5 2.4e-11 43.5 0.5 1.8 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV COG2 PF06148.11 CRK34510.1 - 8.9e-06 25.8 0.7 1.1e-05 25.5 0.7 1.1 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Gp58 PF07902.11 CRK34510.1 - 0.0016 16.9 0.4 0.0019 16.6 0.4 1.0 1 0 0 1 1 1 1 gp58-like protein FliT PF05400.13 CRK34510.1 - 0.0094 16.7 2.4 0.026 15.3 0.3 2.0 1 1 1 2 2 2 1 Flagellar protein FliT ERp29 PF07749.12 CRK34510.1 - 0.0098 16.8 0.7 0.014 16.3 0.7 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain CENP-Q PF13094.6 CRK34510.1 - 0.014 15.6 1.3 0.016 15.4 1.3 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Occludin_ELL PF07303.13 CRK34510.1 - 0.074 13.8 1.6 0.1 13.3 1.6 1.3 1 0 0 1 1 1 0 Occludin homology domain DUF192 PF02643.15 CRK34510.1 - 0.14 12.3 0.2 0.32 11.2 0.1 1.5 2 0 0 2 2 2 0 Uncharacterized ACR, COG1430 DUF4407 PF14362.6 CRK34510.1 - 0.18 11.2 1.1 0.2 11.0 1.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ZYG-11_interact PF05884.12 CRK34510.1 - 0.19 11.1 0.1 0.2 11.0 0.1 1.0 1 0 0 1 1 1 0 Interactor of ZYG-11 ABC2_membrane PF01061.24 CRK34511.1 - 3.7e-12 46.1 7.6 4.1e-12 46.0 7.6 1.0 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 CRK34511.1 - 0.0024 17.0 2.2 0.0024 17.0 2.2 1.0 1 0 0 1 1 1 1 ABC-2 family transporter protein Trehalase PF01204.18 CRK34512.1 - 2.2e-40 139.0 0.0 2.5e-40 138.8 0.0 1.0 1 0 0 1 1 1 1 Trehalase GDE_C PF06202.14 CRK34512.1 - 0.012 14.6 0.1 0.014 14.4 0.1 1.0 1 0 0 1 1 1 0 Amylo-alpha-1,6-glucosidase Ppx-GppA PF02541.16 CRK34513.1 - 0.074 12.5 0.0 0.081 12.3 0.0 1.1 1 0 0 1 1 1 0 Ppx/GppA phosphatase family TPR_1 PF00515.28 CRK34514.1 - 4.2e-17 61.2 0.1 6.1e-05 22.7 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 CRK34514.1 - 5.5e-16 57.4 0.1 1.1e-05 25.3 0.0 3.6 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CRK34514.1 - 4.9e-10 38.7 0.3 0.012 15.7 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 CRK34514.1 - 3.3e-09 36.3 0.8 3.6e-07 29.8 0.1 2.8 2 1 1 3 3 3 1 TPR repeat TPR_16 PF13432.6 CRK34514.1 - 3.7e-08 33.9 0.3 1.6e-06 28.7 0.3 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 CRK34514.1 - 2.1e-07 31.2 0.2 0.00077 20.1 0.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 CRK34514.1 - 3.5e-05 23.5 3.6 0.032 14.2 0.0 3.5 4 1 0 4 4 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CRK34514.1 - 7.6e-05 22.9 1.8 0.088 13.1 0.1 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CRK34514.1 - 0.0046 17.1 0.2 0.0092 16.2 0.2 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 Say1_Mug180 PF10340.9 CRK34514.1 - 0.016 14.1 0.0 0.02 13.8 0.0 1.1 1 0 0 1 1 1 0 Steryl acetyl hydrolase TPR_15 PF13429.6 CRK34514.1 - 0.021 14.1 0.2 0.029 13.6 0.2 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.6 CRK34514.1 - 0.035 14.6 0.0 1.5 9.4 0.0 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 CRK34514.1 - 0.043 14.5 0.2 37 5.3 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Med12 PF09497.10 CRK34517.1 - 1.1e-18 67.3 0.0 1.1e-18 67.3 0.0 1.5 2 0 0 2 2 2 1 Transcription mediator complex subunit Med12 Pribosyltran_N PF13793.6 CRK34518.1 - 4.3e-36 123.4 0.2 5e-36 123.2 0.2 1.1 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase CtaG_Cox11 PF04442.14 CRK34520.1 - 3.6e-53 179.6 0.1 4.3e-53 179.4 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Toxin_28 PF08115.11 CRK34521.1 - 0.12 12.2 1.0 0.12 12.2 1.0 1.5 1 1 0 1 1 1 0 SFI toxin family Xan_ur_permease PF00860.20 CRK34522.1 - 2.7e-10 39.5 7.0 4e-08 32.4 7.0 2.0 1 1 0 1 1 1 1 Permease family WD40 PF00400.32 CRK34532.1 - 5.1e-10 39.8 7.5 5.3e-06 27.1 0.5 3.2 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK34532.1 - 4e-06 27.0 0.5 0.00054 20.2 0.1 2.7 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 CRK34532.1 - 0.0034 16.3 0.2 0.0042 16.1 0.2 1.1 1 0 0 1 1 1 1 Partner and localizer of BRCA2 WD40 domain SAPS PF04499.15 CRK34539.1 - 1.8e-10 40.2 0.2 1.8e-10 40.2 0.2 1.4 2 0 0 2 2 2 1 SIT4 phosphatase-associated protein DUF3825 PF12873.7 CRK34539.1 - 0.052 13.0 0.0 0.061 12.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3825) Spem1 PF15670.5 CRK34543.1 - 2.3 7.7 11.4 2.9 7.4 11.4 1.1 1 0 0 1 1 1 0 Spermatid maturation protein 1 DUF1179 PF06678.11 CRK34544.1 - 0.47 10.5 4.3 0.48 10.4 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1179) CLZ PF16526.5 CRK34546.1 - 0.018 15.4 0.2 0.03 14.7 0.2 1.5 1 1 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Mistic PF11458.8 CRK34546.1 - 0.039 13.9 0.1 0.065 13.2 0.1 1.4 1 0 0 1 1 1 0 Membrane-integrating protein Mistic PhoU PF01895.19 CRK34546.1 - 0.085 13.3 0.1 0.11 12.9 0.1 1.3 1 0 0 1 1 1 0 PhoU domain DUF4209 PF13910.6 CRK34546.1 - 0.16 12.2 0.5 0.82 9.9 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4209) HEAT PF02985.22 CRK34547.1 - 6.9e-10 38.3 0.1 3.9e-06 26.7 0.0 2.2 2 0 0 2 2 2 2 HEAT repeat HEAT_EZ PF13513.6 CRK34547.1 - 5.5e-08 33.2 0.1 1.6e-07 31.7 0.0 1.7 1 1 1 2 2 2 2 HEAT-like repeat DUF3385 PF11865.8 CRK34547.1 - 1.6e-06 28.2 0.3 0.0025 17.7 0.3 2.0 2 0 0 2 2 2 2 Domain of unknown function (DUF3385) HEAT_2 PF13646.6 CRK34547.1 - 2.1e-06 28.0 0.0 2.7e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 HEAT repeats HEAT_PBS PF03130.16 CRK34547.1 - 0.13 13.0 0.5 26 5.9 0.0 2.9 2 2 0 2 2 2 0 PBS lyase HEAT-like repeat IFRD PF05004.13 CRK34547.1 - 0.13 11.3 0.0 0.14 11.2 0.0 1.3 1 1 0 1 1 1 0 Interferon-related developmental regulator (IFRD) Vitellogenin_N PF01347.22 CRK34547.1 - 0.19 10.1 0.0 0.2 10.0 0.0 1.1 1 0 0 1 1 1 0 Lipoprotein amino terminal region SIS PF01380.22 CRK34549.1 - 1.6e-06 28.0 0.0 1.8e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 SIS domain DICT PF10069.9 CRK34549.1 - 0.073 12.8 0.0 0.073 12.8 0.0 1.1 1 0 0 1 1 1 0 Sensory domain in DIguanylate Cyclases and Two-component system HisKA PF00512.25 CRK34557.1 - 3.9e-18 65.3 0.6 1.7e-17 63.2 0.6 2.3 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 CRK34557.1 - 4.4e-11 43.2 0.2 1.7e-10 41.3 0.0 2.2 2 0 0 2 2 2 1 GAF domain GAF PF01590.26 CRK34557.1 - 2.3e-09 38.0 0.8 2e-08 34.9 0.0 2.9 3 0 0 3 3 3 1 GAF domain TPR_8 PF13181.6 CRK34557.1 - 0.0041 17.2 0.3 0.2 12.0 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat HATPase_c PF02518.26 CRK34557.1 - 0.072 13.6 0.0 0.21 12.1 0.0 1.8 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TPR_MalT PF17874.1 CRK34557.1 - 4.2 6.6 10.9 3 7.1 0.3 2.6 3 0 0 3 3 3 0 MalT-like TPR region TPR_2 PF07719.17 CRK34557.1 - 4.5 7.6 9.5 6.6 7.1 0.0 4.6 6 0 0 6 6 6 0 Tetratricopeptide repeat NAD_binding_8 PF13450.6 CRK34558.1 - 8e-09 35.6 0.1 1.8e-08 34.5 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 CRK34558.1 - 1.2e-08 34.7 0.0 1.9e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 CRK34558.1 - 0.0018 17.5 0.1 0.02 14.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CRK34558.1 - 0.0053 16.1 0.1 0.0098 15.2 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CRK34558.1 - 0.013 14.8 0.1 0.023 14.0 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 CRK34558.1 - 0.018 14.3 0.1 0.044 13.0 0.1 1.6 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 CRK34558.1 - 0.02 13.6 0.1 0.031 13.0 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein DAO PF01266.24 CRK34558.1 - 0.025 14.2 0.0 0.047 13.3 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 CRK34558.1 - 0.072 12.1 0.4 0.13 11.3 0.1 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_oxidored PF12831.7 CRK34558.1 - 0.073 12.4 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF1344 PF07076.11 CRK34558.1 - 0.095 12.6 0.1 0.2 11.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1344) NAD_binding_9 PF13454.6 CRK34558.1 - 0.095 12.7 0.1 1 9.3 0.0 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 CRK34558.1 - 0.11 11.5 0.1 0.18 10.9 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain TrkA_N PF02254.18 CRK34558.1 - 0.17 12.2 0.0 0.41 10.9 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain TPT PF03151.16 CRK34559.1 - 5.3e-25 88.3 26.4 6.6e-25 88.0 26.4 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CRK34559.1 - 0.26 11.5 41.8 0.16 12.1 13.1 2.5 3 0 0 3 3 3 0 EamA-like transporter family Ribosomal_L27e PF01777.18 CRK34560.1 - 2.7e-14 53.3 0.4 3e-14 53.1 0.4 1.0 1 0 0 1 1 1 1 Ribosomal L27e protein family Ribosomal_L27e PF01777.18 CRK34561.1 - 6.2e-37 125.8 4.2 9.5e-37 125.2 4.2 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family NCE101 PF11654.8 CRK34562.1 - 2.9e-09 36.5 0.0 3.5e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Non-classical export protein 1 CPP1-like PF11833.8 CRK34562.1 - 0.097 12.3 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Chs7 PF12271.8 CRK34563.1 - 2.3e-113 378.4 2.4 2.6e-113 378.2 2.4 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone DUF2569 PF10754.9 CRK34563.1 - 0.13 12.7 13.2 1.9 8.9 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) Glyoxalase PF00903.25 CRK34564.1 - 0.00022 21.4 0.0 0.00028 21.1 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 CRK34564.1 - 0.0068 16.7 0.0 0.012 15.9 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Ssl1 PF04056.14 CRK34565.1 - 2.4e-104 347.2 0.0 3.3e-71 239.1 0.0 2.1 2 0 0 2 2 2 2 Ssl1-like C1_4 PF07975.12 CRK34565.1 - 8.8e-17 61.1 8.2 8.8e-17 61.1 8.2 2.8 2 1 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.6 CRK34565.1 - 4.1e-14 53.1 0.0 1.9e-13 50.9 0.0 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain CD24 PF14984.6 CRK34565.1 - 0.19 12.0 0.8 24 5.2 0.1 2.5 2 0 0 2 2 2 0 CD24 protein Zn-ribbon_8 PF09723.10 CRK34565.1 - 0.35 11.0 16.7 0.99 9.6 5.5 3.0 2 0 0 2 2 2 0 Zinc ribbon domain zf-CCHC_2 PF13696.6 CRK34565.1 - 0.62 9.9 4.1 1.1 9.2 0.3 2.7 2 0 0 2 2 2 0 Zinc knuckle zinc_ribbon_15 PF17032.5 CRK34565.1 - 8.7 7.2 12.5 1.1 10.1 3.9 2.6 1 1 1 2 2 2 0 zinc-ribbon family Glyoxalase PF00903.25 CRK34566.1 - 3.5e-22 79.0 0.1 1.1e-14 54.8 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 CRK34566.1 - 2.2e-14 53.6 0.1 5.5e-07 29.8 0.1 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 CRK34566.1 - 2.2e-06 27.9 0.0 0.079 13.1 0.0 3.2 3 0 0 3 3 3 2 Glyoxalase-like domain Glyoxalase_5 PF14696.6 CRK34566.1 - 0.0015 18.7 0.1 0.0042 17.3 0.1 1.7 2 0 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal PNRC PF15365.6 CRK34566.1 - 0.083 12.7 4.2 0.23 11.3 4.2 1.8 1 0 0 1 1 1 0 Proline-rich nuclear receptor coactivator motif Ssl1 PF04056.14 CRK34567.1 - 5.5e-49 166.6 0.0 8.6e-49 166.0 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like Chs7 PF12271.8 CRK34567.1 - 1.2e-32 113.4 0.0 1.8e-32 112.9 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase export chaperone C1_4 PF07975.12 CRK34567.1 - 3.7e-16 59.1 9.9 3.7e-16 59.1 9.9 2.6 2 1 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.6 CRK34567.1 - 5.9e-09 36.5 0.0 1.2e-08 35.5 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Zn-ribbon_8 PF09723.10 CRK34567.1 - 0.057 13.6 16.0 0.21 11.7 4.9 3.0 2 0 0 2 2 2 0 Zinc ribbon domain Gram_pos_anchor PF00746.21 CRK34567.1 - 0.23 11.4 0.8 0.51 10.3 0.8 1.6 1 0 0 1 1 1 0 LPXTG cell wall anchor motif zf-CCHC_2 PF13696.6 CRK34567.1 - 0.31 10.9 4.1 0.78 9.6 0.3 2.8 2 0 0 2 2 2 0 Zinc knuckle Sugar_tr PF00083.24 CRK34568.1 - 1.8e-105 353.4 18.6 2.1e-105 353.2 18.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK34568.1 - 2.1e-27 96.0 55.3 1.3e-25 90.1 28.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 CRK34568.1 - 1.7e-08 33.5 20.0 8e-06 24.7 4.6 3.1 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.7 CRK34568.1 - 0.012 14.5 10.5 0.05 12.4 0.2 2.4 2 0 0 2 2 2 0 MFS_1 like family PITH PF06201.13 CRK34569.1 - 2.1e-25 89.7 0.0 2.5e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 PITH domain Sugar_tr PF00083.24 CRK34570.1 - 9.3e-106 354.4 18.7 1.1e-105 354.1 18.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK34570.1 - 3.3e-28 98.7 54.0 1.6e-26 93.1 26.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 CRK34570.1 - 1.2e-08 33.9 19.7 8.3e-06 24.6 4.6 3.1 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.7 CRK34570.1 - 0.0065 15.4 9.9 0.046 12.6 0.2 2.4 2 0 0 2 2 2 2 MFS_1 like family Rrn6 PF10214.9 CRK34571.1 - 2.1e-257 857.0 0.3 2e-128 430.2 0.2 2.1 2 0 0 2 2 2 2 RNA polymerase I-specific transcription-initiation factor zinc_ribbon_6 PF14599.6 CRK34571.1 - 4.4e-48 161.1 0.4 2.6e-23 81.8 0.1 2.9 2 0 0 2 2 2 2 Zinc-ribbon PITH PF06201.13 CRK34571.1 - 7.3e-43 146.4 0.0 6.4e-41 140.1 0.0 2.3 2 0 0 2 2 2 1 PITH domain Ras PF00071.22 CRK34571.1 - 1.1e-07 31.6 0.0 6.2e-07 29.2 0.0 2.2 2 0 0 2 2 2 1 Ras family zf-RING_2 PF13639.6 CRK34571.1 - 1e-06 29.0 9.7 1e-06 29.0 9.7 3.3 4 0 0 4 4 3 1 Ring finger domain Roc PF08477.13 CRK34571.1 - 1.1e-06 28.9 0.0 2.4e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase zf-RING_UBOX PF13445.6 CRK34571.1 - 2.2e-05 24.4 5.7 0.0001 22.2 5.7 2.3 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CRK34571.1 - 0.00011 22.0 7.8 0.00011 22.0 7.8 3.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CRK34571.1 - 0.0003 20.6 4.9 0.0003 20.6 4.9 3.1 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CRK34571.1 - 0.00047 20.1 11.8 0.00047 20.1 11.8 3.8 3 0 0 3 3 3 1 zinc-RING finger domain DUF3606 PF12244.8 CRK34571.1 - 0.022 14.7 0.1 6.2 6.8 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3606) MucB_RseB PF03888.14 CRK34571.1 - 0.29 10.6 1.0 17 4.9 0.1 2.4 2 0 0 2 2 2 0 MucB/RseB N-terminal domain zf-RING_4 PF14570.6 CRK34571.1 - 0.31 10.9 4.7 0.74 9.7 4.7 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain SDA1 PF05285.12 CRK34571.1 - 0.43 10.0 3.6 0.8 9.1 3.6 1.3 1 0 0 1 1 1 0 SDA1 zf-C3HC4_3 PF13920.6 CRK34571.1 - 0.92 9.4 28.4 0.62 10.0 16.9 3.7 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.6 CRK34571.1 - 0.95 9.4 8.7 5.4 7.0 6.9 3.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 MOZART1 PF12554.8 CRK34572.1 - 1.1e-25 89.1 0.9 1.3e-25 88.9 0.9 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated MOZART1 PF12554.8 CRK34573.1 - 1.1e-25 89.1 0.9 1.3e-25 88.9 0.9 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated PMT PF02366.18 CRK34574.1 - 3e-108 361.0 16.0 4.7e-84 281.8 12.1 2.4 2 0 0 2 2 2 2 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.19 CRK34574.1 - 2.1e-73 246.1 8.5 2.8e-36 125.1 1.0 2.2 2 0 0 2 2 2 2 MIR domain PMT_4TMC PF16192.5 CRK34574.1 - 2.9e-71 239.2 13.7 4.4e-37 127.6 3.0 3.7 2 1 1 3 3 3 3 C-terminal four TMM region of protein-O-mannosyltransferase NicO PF03824.16 CRK34574.1 - 0.0053 16.1 2.9 12 5.1 0.6 3.3 3 0 0 3 3 3 3 High-affinity nickel-transport protein FlaE PF07559.14 CRK34574.1 - 0.015 15.9 0.7 8.6 7.0 0.1 2.6 2 0 0 2 2 2 0 Flagellar basal body protein FlaE DUF1722 PF08349.11 CRK34574.1 - 0.081 13.2 0.1 25 5.2 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) DUF2976 PF11190.8 CRK34574.1 - 0.16 11.8 2.1 1.4 8.8 0.6 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) FtsX PF02687.21 CRK34574.1 - 4.9 7.7 15.3 1.7 9.1 4.4 3.7 3 0 0 3 3 3 0 FtsX-like permease family Bac_luciferase PF00296.20 CRK34575.1 - 2.7e-65 220.9 0.1 3.5e-65 220.5 0.1 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Haem_degrading PF03928.14 CRK34575.1 - 1.5e-18 67.0 0.0 2.9e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 Haem-degrading Choline_transpo PF04515.12 CRK34576.1 - 1.5e-22 80.2 28.3 1.5e-22 80.2 28.3 2.9 2 1 0 2 2 2 1 Plasma-membrane choline transporter WW PF00397.26 CRK34576.1 - 3.5e-10 39.8 5.5 8e-10 38.6 5.5 1.7 1 0 0 1 1 1 1 WW domain DUF2012 PF09430.10 CRK34577.1 - 9.8e-22 77.4 0.0 1.6e-21 76.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) p450 PF00067.22 CRK34578.1 - 4.5e-63 213.6 0.0 5.9e-63 213.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 POT1PC PF16686.5 CRK34578.1 - 0.13 12.1 0.1 1 9.2 0.1 2.0 1 1 0 1 1 1 0 ssDNA-binding domain of telomere protection protein Cupin_8 PF13621.6 CRK34578.1 - 0.14 11.9 0.1 2.3 7.9 0.0 2.1 2 0 0 2 2 2 0 Cupin-like domain Cys_Met_Meta_PP PF01053.20 CRK34579.1 - 1.8e-150 500.8 0.0 2e-150 500.6 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 CRK34579.1 - 2.8e-12 46.6 0.1 5.5e-12 45.7 0.1 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 CRK34579.1 - 7.9e-11 41.7 0.0 2e-10 40.4 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class I and II Aminotran_5 PF00266.19 CRK34579.1 - 2.4e-08 33.3 0.4 5.1e-08 32.3 0.4 1.5 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 CRK34579.1 - 2.8e-05 23.5 0.0 5.5e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 CRK34579.1 - 0.012 14.2 0.1 0.017 13.6 0.1 1.2 1 0 0 1 1 1 0 Methionine gamma-lyase SepSecS PF05889.13 CRK34579.1 - 0.027 13.2 0.0 0.04 12.6 0.0 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Asparaginase_C PF17763.1 CRK34579.1 - 0.17 12.1 0.1 0.52 10.6 0.0 1.8 2 0 0 2 2 2 0 Glutaminase/Asparaginase C-terminal domain DASH_Dad2 PF08654.10 CRK34579.1 - 0.18 12.2 0.0 3 8.3 0.0 2.4 1 1 1 2 2 2 0 DASH complex subunit Dad2 Peptidase_C12 PF01088.21 CRK34580.1 - 1.9e-60 204.2 0.0 2.8e-60 203.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Xan_ur_permease PF00860.20 CRK34580.1 - 2.8e-15 55.9 17.0 1e-14 54.1 15.4 2.3 1 1 0 1 1 1 1 Permease family UCH_C PF18031.1 CRK34580.1 - 1.7e-10 40.6 0.0 3.7e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases Sulfate_transp PF00916.20 CRK34580.1 - 2.5e-05 23.2 2.6 2.5e-05 23.2 2.6 1.8 2 1 0 2 2 2 1 Sulfate permease family Dicty_CAR PF05462.11 CRK34582.1 - 1.4e-10 40.8 7.3 1.4e-10 40.8 7.3 1.8 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.24 CRK34582.1 - 2.9e-10 39.8 9.5 1.1e-09 38.0 8.4 2.2 2 1 0 2 2 2 1 7 transmembrane receptor (Secretin family) 7tm_1 PF00001.21 CRK34582.1 - 2.9e-07 30.1 0.3 4.8e-07 29.4 0.3 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.8 CRK34582.1 - 9e-06 25.6 7.1 9e-06 25.6 7.1 1.7 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 Frizzled PF01534.17 CRK34582.1 - 3.2e-05 23.1 8.7 0.0011 18.1 8.7 2.2 1 1 0 1 1 1 1 Frizzled/Smoothened family membrane region zf-LITAF-like PF10601.9 CRK34582.1 - 4.5 7.6 0.0 4.5 7.6 0.0 3.3 4 0 0 4 4 4 0 LITAF-like zinc ribbon domain Fibrillarin PF01269.17 CRK34584.1 - 1.7e-101 338.1 0.0 2.1e-101 337.8 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 CRK34584.1 - 0.00022 21.0 0.1 0.00039 20.2 0.1 1.3 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Ribosomal_L22 PF00237.19 CRK34585.1 - 1.6e-39 134.3 0.0 2.2e-39 133.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e LTD PF00932.19 CRK34585.1 - 0.15 12.4 0.0 0.19 12.1 0.0 1.5 1 1 0 1 1 1 0 Lamin Tail Domain CASP_C PF08172.12 CRK34586.1 - 1.5e-52 178.5 13.1 2e-51 174.8 0.0 2.7 3 0 0 3 3 3 1 CASP C terminal DUF3455 PF11937.8 CRK34586.1 - 7.3e-42 143.4 0.1 1.9e-41 142.1 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) LMBR1 PF04791.16 CRK34586.1 - 0.036 13.0 0.0 0.036 13.0 0.0 2.4 2 1 0 2 2 2 0 LMBR1-like membrane protein TolA_bind_tri PF16331.5 CRK34586.1 - 0.2 11.7 33.0 0.056 13.5 0.6 5.2 6 0 0 6 6 6 0 TolA binding protein trimerisation PI3K_P85_iSH2 PF16454.5 CRK34586.1 - 0.39 10.3 28.9 0.27 10.8 1.7 4.4 2 1 1 4 4 4 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain STAT_alpha PF01017.20 CRK34586.1 - 0.51 10.2 0.0 0.51 10.2 0.0 3.7 3 1 1 4 4 4 0 STAT protein, all-alpha domain MscS_porin PF12795.7 CRK34586.1 - 1.2 8.6 37.6 1.1 8.7 1.5 4.5 4 0 0 4 4 4 0 Mechanosensitive ion channel porin domain PRKG1_interact PF15898.5 CRK34586.1 - 3.2 8.7 45.1 8 7.4 1.1 5.7 5 0 0 5 5 5 0 cGMP-dependent protein kinase interacting domain Cep57_MT_bd PF06657.13 CRK34586.1 - 6.3 7.3 27.7 0.68 10.4 2.5 4.9 5 0 0 5 5 5 0 Centrosome microtubule-binding domain of Cep57 Fez1 PF06818.15 CRK34586.1 - 8 6.9 46.8 1.7 9.1 19.2 4.2 1 1 2 3 3 3 0 Fez1 Choline_sulf_C PF12411.8 CRK34588.1 - 0.0026 17.5 0.1 4.9 7.1 0.0 2.9 2 0 0 2 2 2 2 Choline sulfatase enzyme C terminal SHIRT PF18655.1 CRK34588.1 - 0.034 14.7 0.0 15 6.3 0.0 2.5 2 0 0 2 2 2 0 SHIRT domain Vps39_1 PF10366.9 CRK34588.1 - 0.083 13.2 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 CASP_C PF08172.12 CRK34589.1 - 3.7e-94 314.8 21.2 3.8e-94 314.7 0.0 3.7 3 1 1 4 4 4 1 CASP C terminal TolA_bind_tri PF16331.5 CRK34589.1 - 0.00014 21.9 34.4 0.078 13.1 0.4 5.8 6 0 0 6 6 6 3 TolA binding protein trimerisation LMBR1 PF04791.16 CRK34589.1 - 0.00077 18.5 0.0 0.00077 18.5 0.0 2.6 2 1 1 3 3 3 1 LMBR1-like membrane protein STAT_alpha PF01017.20 CRK34589.1 - 0.0034 17.3 17.8 0.017 15.0 0.0 4.1 3 2 1 4 4 4 1 STAT protein, all-alpha domain bZIP_2 PF07716.15 CRK34589.1 - 0.011 15.8 4.3 0.011 15.8 4.3 7.5 8 1 0 8 8 8 0 Basic region leucine zipper ZapB PF06005.12 CRK34589.1 - 0.014 15.8 6.6 0.014 15.8 6.6 6.4 5 1 1 6 6 5 0 Cell division protein ZapB DUF4164 PF13747.6 CRK34589.1 - 0.022 15.0 0.9 0.022 15.0 0.9 5.6 5 1 0 5 5 5 0 Domain of unknown function (DUF4164) Fez1 PF06818.15 CRK34589.1 - 0.023 15.2 47.4 0.61 10.5 19.5 4.5 3 1 2 5 5 5 0 Fez1 HAP1_N PF04849.13 CRK34589.1 - 0.073 12.3 0.1 0.073 12.3 0.1 4.9 2 1 1 4 4 4 0 HAP1 N-terminal conserved region NAD_binding_1 PF00175.21 CRK34589.1 - 0.17 12.5 4.7 25 5.6 0.0 4.1 4 0 0 4 4 4 0 Oxidoreductase NAD-binding domain PRKG1_interact PF15898.5 CRK34589.1 - 0.33 11.9 53.1 1.3 10.0 1.3 5.8 6 0 0 6 6 5 0 cGMP-dependent protein kinase interacting domain SlyX PF04102.12 CRK34589.1 - 0.38 11.4 0.0 0.38 11.4 0.0 6.2 7 0 0 7 7 6 0 SlyX Cep57_MT_bd PF06657.13 CRK34589.1 - 0.51 10.8 35.6 0.18 12.3 1.8 6.3 5 1 2 7 7 7 0 Centrosome microtubule-binding domain of Cep57 YabA PF06156.13 CRK34589.1 - 1.7 9.3 36.5 1.4 9.6 0.1 6.0 3 2 0 5 5 5 0 Initiation control protein YabA MscS_porin PF12795.7 CRK34589.1 - 1.8 8.1 47.5 0.22 11.1 3.2 4.5 4 1 0 4 4 4 0 Mechanosensitive ion channel porin domain Filament PF00038.21 CRK34589.1 - 2.9 7.4 50.3 1.3 8.5 0.3 3.7 3 1 1 4 4 4 0 Intermediate filament protein SKA1 PF07160.12 CRK34589.1 - 3.2 7.5 26.9 7.2 6.4 0.4 4.7 3 1 0 4 4 4 0 Spindle and kinetochore-associated protein 1 Golgin_A5 PF09787.9 CRK34589.1 - 3.3 7.1 49.2 0.86 9.0 0.1 4.8 3 1 1 5 5 5 0 Golgin subfamily A member 5 DUF1664 PF07889.12 CRK34589.1 - 5.3 7.1 26.9 6.3 6.9 1.0 5.6 4 1 0 5 5 5 0 Protein of unknown function (DUF1664) ADIP PF11559.8 CRK34589.1 - 8.3 6.5 61.3 0.095 12.8 6.1 6.8 5 2 2 7 7 7 0 Afadin- and alpha -actinin-Binding CENP-H PF05837.12 CRK34589.1 - 9.7 6.6 48.9 0.22 12.0 0.4 5.8 5 1 1 6 6 6 0 Centromere protein H (CENP-H) DUF3455 PF11937.8 CRK34590.1 - 5.5e-35 121.1 0.1 4e-19 69.5 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3455) DUF2990 PF11693.8 CRK34590.1 - 0.0056 16.8 1.2 0.017 15.3 0.6 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF2990) Ribosomal_L22 PF00237.19 CRK34592.1 - 1e-39 134.9 0.0 1.5e-39 134.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Fibrillarin PF01269.17 CRK34593.1 - 1.1e-101 338.7 0.0 1.4e-101 338.4 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 CRK34593.1 - 0.00035 20.3 0.1 0.00067 19.4 0.1 1.3 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit 7tm_2 PF00002.24 CRK34594.1 - 2.8e-10 39.9 9.9 1.5e-09 37.5 8.4 2.5 2 1 0 2 2 2 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 CRK34594.1 - 3.5e-10 39.5 7.4 3.5e-10 39.5 7.4 1.8 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor 7tm_1 PF00001.21 CRK34594.1 - 4.6e-07 29.4 0.3 7.5e-07 28.7 0.3 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.8 CRK34594.1 - 2e-06 27.7 7.1 5.5e-06 26.3 7.1 1.7 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Frizzled PF01534.17 CRK34594.1 - 1.2e-05 24.5 1.0 1.2e-05 24.5 1.0 2.2 1 1 1 2 2 2 1 Frizzled/Smoothened family membrane region zf-LITAF-like PF10601.9 CRK34594.1 - 3.8 7.8 0.0 3.8 7.8 0.0 3.3 4 0 0 4 4 4 0 LITAF-like zinc ribbon domain Xan_ur_permease PF00860.20 CRK34596.1 - 2.2e-28 99.1 30.7 7.3e-27 94.1 27.9 3.2 1 1 0 1 1 1 1 Permease family MFS_MOT1 PF16983.5 CRK34596.1 - 0.0046 17.4 1.2 0.0046 17.4 1.2 3.3 3 0 0 3 3 3 2 Molybdate transporter of MFS superfamily Peptidase_C12 PF01088.21 CRK34597.1 - 1.1e-61 208.2 0.0 2.3e-61 207.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 CRK34597.1 - 2.3e-10 40.2 0.0 6.5e-10 38.8 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases CLP_protease PF00574.23 CRK34598.1 - 1.1e-68 230.8 0.0 1.4e-68 230.4 0.0 1.1 1 0 0 1 1 1 1 Clp protease ILVD_EDD PF00920.21 CRK34600.1 - 6.2e-213 708.1 0.1 7.2e-213 707.9 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family Kinesin PF00225.23 CRK34601.1 - 1.7e-105 352.6 0.5 3.9e-105 351.5 0.5 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CRK34601.1 - 2.3e-55 186.7 0.1 7.2e-55 185.0 0.1 1.9 1 0 0 1 1 1 1 Microtubule binding AAA_24 PF13479.6 CRK34601.1 - 0.0015 18.3 0.0 0.004 16.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CRK34601.1 - 0.12 12.8 0.0 0.12 12.8 0.0 2.9 2 1 0 2 2 2 0 AAA ATPase domain Lebercilin PF15619.6 CRK34601.1 - 0.41 10.3 48.1 1.7 8.3 22.5 3.1 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease FlaC_arch PF05377.11 CRK34601.1 - 3.1 8.3 18.4 2.1 8.8 0.6 5.0 5 1 0 5 5 5 0 Flagella accessory protein C (FlaC) Baculo_p24 PF05073.12 CRK34601.1 - 3.8 7.3 11.3 0.27 11.0 0.4 2.9 2 1 1 3 3 3 0 Baculovirus P24 capsid protein ADIP PF11559.8 CRK34601.1 - 7.2 6.7 51.5 0.93 9.6 4.1 4.3 2 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding GNT-I PF03071.15 CRK34602.1 - 0.077 11.7 0.1 0.11 11.3 0.1 1.1 1 0 0 1 1 1 0 GNT-I family Coilin_N PF15862.5 CRK34603.1 - 0.0083 15.9 13.7 0.0083 15.9 13.7 3.5 1 1 2 3 3 3 1 Coilin N-terminus Mitofilin PF09731.9 CRK34603.1 - 1.3 7.8 48.1 1.6 7.5 48.1 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein LAP1C PF05609.12 CRK34603.1 - 1.9 7.5 30.1 2.6 7.0 30.1 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) GREB1 PF15782.5 CRK34603.1 - 5.1 4.1 25.8 6.2 3.8 25.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Thioesterase PF00975.20 CRK34605.1 - 7.6e-16 58.9 0.0 1.7e-15 57.8 0.0 1.5 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 CRK34605.1 - 3.3e-07 31.1 0.9 3.7e-07 31.0 0.9 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 CRK34605.1 - 0.0011 18.8 0.0 0.0015 18.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 CRK34605.1 - 0.027 14.3 0.0 0.037 13.8 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Coilin_N PF15862.5 CRK34606.1 - 0.0061 16.4 14.3 0.0061 16.4 14.3 3.6 1 1 2 3 3 3 1 Coilin N-terminus Mitofilin PF09731.9 CRK34606.1 - 0.71 8.6 61.8 0.94 8.2 61.8 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Hamartin PF04388.12 CRK34606.1 - 6.2 5.3 24.6 8.1 5.0 24.6 1.3 1 0 0 1 1 1 0 Hamartin protein BSP_II PF05432.11 CRK34606.1 - 9.2 5.9 52.2 13 5.3 52.2 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) GNT-I PF03071.15 CRK34607.1 - 0.069 11.9 0.0 0.099 11.4 0.0 1.1 1 0 0 1 1 1 0 GNT-I family Kinesin PF00225.23 CRK34608.1 - 8.6e-105 350.3 0.5 1.4e-104 349.7 0.5 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CRK34608.1 - 6.3e-55 185.2 0.1 1.1e-54 184.4 0.1 1.4 1 0 0 1 1 1 1 Microtubule binding FlaC_arch PF05377.11 CRK34608.1 - 0.011 16.1 5.6 5.6 7.5 0.6 4.2 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) AAA_24 PF13479.6 CRK34608.1 - 0.011 15.4 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain bZIP_1 PF00170.21 CRK34608.1 - 0.16 12.1 0.1 0.16 12.1 0.1 4.5 4 1 1 5 5 5 0 bZIP transcription factor SRA PF18491.1 CRK34608.1 - 0.19 11.9 0.4 29 4.7 0.0 3.2 3 0 0 3 3 3 0 SET and RING associated domain AAA_22 PF13401.6 CRK34608.1 - 0.63 10.3 2.2 1 9.6 0.0 2.6 3 0 0 3 3 3 0 AAA domain Baculo_p24 PF05073.12 CRK34608.1 - 2.4 7.9 3.9 0.68 9.7 0.4 1.9 2 0 0 2 2 2 0 Baculovirus P24 capsid protein DUF3584 PF12128.8 CRK34608.1 - 7.6 3.9 27.0 1.3 6.4 16.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) ILVD_EDD PF00920.21 CRK34610.1 - 1.7e-212 706.7 0.2 2e-212 706.4 0.2 1.0 1 0 0 1 1 1 1 Dehydratase family Sipho_tail PF05709.11 CRK34610.1 - 0.1 12.0 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 Phage tail protein STIMATE PF12400.8 CRK34614.1 - 4.8e-41 140.2 3.9 4.8e-41 140.2 3.9 1.6 2 0 0 2 2 2 1 STIMATE family TNFR_16_TM PF18422.1 CRK34614.1 - 0.94 9.5 3.1 42 4.2 1.8 2.5 2 0 0 2 2 2 0 Tumor necrosis factor receptor member 16 trans-membrane domain GP41 PF00517.17 CRK34615.1 - 0.07 13.0 2.3 0.13 12.1 0.1 1.9 2 0 0 2 2 2 0 Retroviral envelope protein Corona_S2 PF01601.16 CRK34615.1 - 0.1 11.1 17.4 0.16 10.4 17.4 1.2 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein FokI_N PF02981.15 CRK34617.1 - 0.22 11.7 0.1 0.37 10.9 0.1 1.3 1 0 0 1 1 1 0 Restriction endonuclease FokI, recognition domain RCR PF12273.8 CRK34620.1 - 3.7e-18 66.3 22.0 6.6e-18 65.5 19.1 2.6 2 1 0 2 2 2 1 Chitin synthesis regulation, resistance to Congo red MLANA PF14991.6 CRK34620.1 - 0.0089 16.3 0.1 0.048 13.9 0.0 2.1 2 0 0 2 2 2 1 Protein melan-A WBP-1 PF11669.8 CRK34620.1 - 0.01 16.4 0.1 0.026 15.1 0.1 1.7 1 0 0 1 1 1 0 WW domain-binding protein 1 EphA2_TM PF14575.6 CRK34620.1 - 0.1 13.5 0.0 0.3 12.0 0.0 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain RCR PF12273.8 CRK34624.1 - 2.5e-19 70.1 21.1 4.5e-18 66.0 21.1 2.1 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red WBP-1 PF11669.8 CRK34624.1 - 0.0044 17.6 0.1 0.0082 16.8 0.1 1.5 1 0 0 1 1 1 1 WW domain-binding protein 1 MLANA PF14991.6 CRK34624.1 - 0.0068 16.7 0.0 0.013 15.8 0.0 1.6 1 0 0 1 1 1 1 Protein melan-A EphA2_TM PF14575.6 CRK34624.1 - 0.047 14.6 0.2 0.096 13.6 0.2 1.7 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Rhabdo_glycop PF00974.18 CRK34624.1 - 0.15 10.5 0.4 0.22 10.0 0.4 1.2 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein DUF4834 PF16118.5 CRK34624.1 - 0.26 12.3 2.3 0.47 11.5 2.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) TMEM52 PF14979.6 CRK34624.1 - 0.28 11.1 0.7 0.4 10.6 0.1 1.5 2 0 0 2 2 2 0 Transmembrane 52 FAA_hydrolase PF01557.18 CRK34626.1 - 7.2e-51 172.9 0.0 8.8e-51 172.6 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family 3-HAO PF06052.12 CRK34627.1 - 3.2e-64 215.1 0.0 3.7e-64 214.9 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 CRK34627.1 - 3.5e-06 26.6 0.0 5.9e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 CRK34627.1 - 4.4e-05 23.1 0.0 7.8e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Cupin DZR PF12773.7 CRK34627.1 - 0.0033 17.4 0.8 0.0076 16.3 0.8 1.6 1 1 0 1 1 1 1 Double zinc ribbon ARD PF03079.14 CRK34627.1 - 0.0044 17.2 0.0 0.0066 16.6 0.0 1.3 1 0 0 1 1 1 1 ARD/ARD' family AraC_binding PF02311.19 CRK34627.1 - 0.029 14.3 0.0 0.05 13.5 0.0 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain Cupin_4 PF08007.12 CRK34627.1 - 0.041 13.4 0.0 0.046 13.2 0.0 1.2 1 0 0 1 1 1 0 Cupin superfamily protein C1_2 PF03107.16 CRK34627.1 - 0.064 13.6 0.3 13 6.2 0.0 2.3 2 0 0 2 2 2 0 C1 domain zinc_ribbon_5 PF13719.6 CRK34627.1 - 0.077 12.8 0.3 0.077 12.8 0.3 1.8 2 0 0 2 2 2 0 zinc-ribbon domain Defensin_2 PF01097.18 CRK34628.1 - 0.0007 19.5 9.6 0.0007 19.5 9.6 1.5 2 0 0 2 2 2 1 Arthropod defensin DUF5456 PF17539.2 CRK34629.1 - 0.16 11.8 0.1 0.96 9.3 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5456) Glyco_hydro_71 PF03659.14 CRK34630.1 - 5.9e-117 390.6 5.1 5.8e-78 262.3 1.7 2.4 1 1 1 2 2 2 2 Glycosyl hydrolase family 71 Ank_2 PF12796.7 CRK34632.1 - 6.1e-22 78.0 0.0 5.4e-07 30.1 0.0 4.6 3 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CRK34632.1 - 8.4e-16 56.5 0.1 0.28 11.9 0.0 8.5 9 0 0 9 9 9 3 Ankyrin repeat Ank_4 PF13637.6 CRK34632.1 - 1.1e-15 57.8 0.2 0.0035 17.9 0.0 6.6 5 3 3 8 8 8 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 CRK34632.1 - 2.2e-14 53.3 0.1 0.00046 20.4 0.2 5.5 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 CRK34632.1 - 1.3e-08 34.9 1.9 1.7 9.2 0.1 6.6 5 3 0 5 5 5 3 Ankyrin repeat Helo_like_N PF17111.5 CRK34632.1 - 1.3e-08 34.5 0.2 2.2e-08 33.7 0.2 1.3 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins SesA PF17107.5 CRK34632.1 - 0.007 16.5 0.0 0.015 15.5 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Ctr PF04145.15 CRK34633.1 - 7.9e-30 104.4 14.9 6.5e-28 98.2 14.9 2.2 1 1 0 1 1 1 1 Ctr copper transporter family MCM PF00493.23 CRK34634.1 - 4.4e-38 130.6 0.0 1.3e-37 129.1 0.0 1.7 2 0 0 2 2 2 1 MCM P-loop domain MCM_lid PF17855.1 CRK34634.1 - 1.1e-30 105.9 3.1 2.7e-30 104.6 3.1 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain AAA_lid_2 PF17863.1 CRK34634.1 - 0.0022 17.8 0.2 0.0049 16.7 0.2 1.5 1 0 0 1 1 1 1 AAA lid domain AAA_32 PF13654.6 CRK34634.1 - 0.022 13.6 0.4 0.039 12.7 0.4 1.3 1 0 0 1 1 1 0 AAA domain Oberon_cc PF16312.5 CRK34634.1 - 0.036 14.0 2.5 0.062 13.2 2.5 1.4 1 0 0 1 1 1 0 Coiled-coil region of Oberon HLH PF00010.26 CRK34634.1 - 0.04 13.9 0.1 0.1 12.5 0.1 1.7 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain Aminotran_5 PF00266.19 CRK34634.1 - 0.049 12.6 0.1 6 5.7 0.0 2.2 2 0 0 2 2 2 0 Aminotransferase class-V WASH-7_N PF14745.6 CRK34634.1 - 0.1 11.1 0.0 0.13 10.7 0.0 1.1 1 0 0 1 1 1 0 WASH complex subunit 7, N-terminal STAS_2 PF13466.6 CRK34634.1 - 0.24 11.8 0.1 0.24 11.8 0.1 2.5 3 0 0 3 3 3 0 STAS domain Ras PF00071.22 CRK34646.1 - 2.2e-30 105.4 0.1 3.3e-30 104.8 0.1 1.2 1 0 0 1 1 1 1 Ras family Porphobil_deam PF01379.20 CRK34646.1 - 9.5e-30 103.6 0.0 1.6e-29 102.9 0.0 1.3 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Roc PF08477.13 CRK34646.1 - 1.8e-23 83.0 0.7 2.7e-23 82.5 0.1 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CRK34646.1 - 3.7e-06 26.5 0.0 6.2e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CRK34646.1 - 0.00096 18.6 0.1 0.0014 18.0 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PQ-loop PF04193.14 CRK34647.1 - 0.11 12.3 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 PQ loop repeat Sec10 PF07393.11 CRK34651.1 - 2e-34 119.1 0.1 2.1e-34 119.0 0.1 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 DUF3383 PF11863.8 CRK34651.1 - 0.048 12.7 0.0 0.053 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3383) TPT PF03151.16 CRK34652.1 - 2.7e-06 26.9 4.8 3.2e-06 26.7 4.8 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family Pkinase PF00069.25 CRK34654.1 - 3.7e-09 36.3 0.0 0.00046 19.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.23 CRK34654.1 - 1.6e-05 25.0 0.1 2.8e-05 24.1 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family AAA_13 PF13166.6 CRK34654.1 - 0.043 12.5 0.6 0.051 12.2 0.6 1.0 1 0 0 1 1 1 0 AAA domain TRF PF08558.10 CRK34654.1 - 0.09 12.4 0.2 0.12 12.0 0.2 1.1 1 0 0 1 1 1 0 Telomere repeat binding factor (TRF) Tropomyosin_1 PF12718.7 CRK34654.1 - 0.093 12.9 5.6 0.13 12.4 5.6 1.2 1 0 0 1 1 1 0 Tropomyosin like DUF812 PF05667.11 CRK34654.1 - 0.11 11.3 2.4 0.15 10.9 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) SpoIIIAH PF12685.7 CRK34654.1 - 0.12 12.2 0.9 0.19 11.6 0.9 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein Tup_N PF08581.10 CRK34654.1 - 0.15 12.4 2.3 0.27 11.6 2.2 1.6 1 1 0 1 1 1 0 Tup N-terminal TMF_DNA_bd PF12329.8 CRK34654.1 - 0.47 10.5 3.3 3.9 7.5 3.3 2.1 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Metal_resist PF13801.6 CRK34654.1 - 1.7 8.9 15.6 0.23 11.6 3.4 3.2 2 2 0 2 2 2 0 Heavy-metal resistance GvpK PF05121.12 CRK34654.1 - 1.9 8.6 4.7 0.62 10.1 1.1 2.1 2 0 0 2 2 2 0 Gas vesicle protein K Esterase_phd PF10503.9 CRK34655.1 - 8.1e-06 25.5 0.7 1.1e-05 25.1 0.7 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Fungal_trans PF04082.18 CRK34660.1 - 8.1e-05 21.8 0.1 8.8e-05 21.7 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Dioxygenase_C PF00775.21 CRK34662.1 - 0.0046 16.4 0.0 0.0056 16.1 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase MDM31_MDM32 PF08118.11 CRK34663.1 - 4.9e-59 200.4 0.1 5.4e-59 200.2 0.1 1.0 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins GET2 PF08690.10 CRK34664.1 - 0.73 9.5 6.3 0.76 9.4 6.3 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 DUF3617 PF12276.8 CRK34664.1 - 3.6 7.9 11.1 7.6 6.9 10.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3617) Cullin PF00888.22 CRK34667.1 - 4.1e-10 38.9 0.0 4.5e-10 38.8 0.0 1.0 1 0 0 1 1 1 1 Cullin family GATase PF00117.28 CRK34668.1 - 1.4e-06 28.2 0.0 1.7e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I DUF2968 PF11180.8 CRK34669.1 - 0.76 9.4 21.6 0.91 9.1 21.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DASH_Spc34 PF08657.10 CRK34669.1 - 0.82 9.4 12.6 0.95 9.2 12.6 1.2 1 0 0 1 1 1 0 DASH complex subunit Spc34 Golgin_A5 PF09787.9 CRK34669.1 - 4.3 6.7 21.2 5.4 6.4 21.2 1.0 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF3292 PF11696.8 CRK34669.1 - 4.6 5.5 12.8 4.8 5.4 12.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Asp-B-Hydro_N PF05279.11 CRK34669.1 - 5 7.1 22.6 5.9 6.9 22.6 1.0 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region UPF0242 PF06785.11 CRK34669.1 - 8.9 6.4 18.9 9.7 6.3 18.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Arrestin_N PF00339.29 CRK34670.1 - 0.0043 17.1 0.0 0.0055 16.8 0.0 1.1 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Septin PF00735.18 CRK34672.1 - 1.1e-37 129.9 0.9 1.2e-37 129.7 0.9 1.0 1 0 0 1 1 1 1 Septin DUF2235 PF09994.9 CRK34673.1 - 1.3e-35 123.2 0.3 1.5e-35 123.0 0.3 1.0 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Ribosomal_S24e PF01282.19 CRK34674.1 - 2.8e-32 110.5 0.0 3.2e-32 110.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S24e SSrecog PF03531.14 CRK34678.1 - 0.08 12.9 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 Structure-specific recognition protein (SSRP1) Ribosomal_S28e PF01200.18 CRK34680.1 - 1.9e-31 107.8 1.9 2.1e-31 107.7 1.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Exo_endo_phos PF03372.23 CRK34682.1 - 0.031 13.8 0.0 0.033 13.7 0.0 1.1 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family ubiquitin PF00240.23 CRK34683.1 - 0.1 12.3 0.3 0.44 10.3 0.0 2.1 2 1 0 2 2 2 0 Ubiquitin family Ribosomal_S8 PF00410.19 CRK34684.1 - 6.5e-08 32.6 0.0 9.4e-07 28.8 0.0 2.0 1 1 0 1 1 1 1 Ribosomal protein S8 SPO11_like PF03533.14 CRK34684.1 - 0.064 13.4 0.8 0.092 12.8 0.1 1.7 2 0 0 2 2 2 0 SPO11 homologue Helicase_C PF00271.31 CRK34686.1 - 0.0031 17.8 0.1 0.0044 17.3 0.1 1.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Lactamase_B_4 PF13691.6 CRK34688.1 - 2.3e-13 49.6 0.1 3.5e-13 49.0 0.1 1.3 1 0 0 1 1 1 1 tRNase Z endonuclease Dynamitin PF04912.14 CRK34689.1 - 4.2e-28 98.8 0.3 4.4e-28 98.7 0.3 1.0 1 0 0 1 1 1 1 Dynamitin FlgN PF05130.12 CRK34689.1 - 0.037 14.5 1.3 0.053 14.0 1.3 1.2 1 0 0 1 1 1 0 FlgN protein NTP_transferase PF00483.23 CRK34706.1 - 4.7e-19 69.0 0.0 5.2e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase ydhR PF08803.11 CRK34706.1 - 0.073 13.0 0.0 0.82 9.6 0.0 2.4 2 0 0 2 2 2 0 Putative mono-oxygenase ydhR PRELI PF04707.14 CRK34707.1 - 3.4e-15 56.2 0.0 4.5e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 PRELI-like family bPH_2 PF03703.14 CRK34707.1 - 0.16 12.2 0.0 0.34 11.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial PH domain Bac_surface_Ag PF01103.23 CRK34709.1 - 3.7e-17 62.8 0.0 4.1e-17 62.7 0.0 1.0 1 0 0 1 1 1 1 Surface antigen Helicase_C PF00271.31 CRK34711.1 - 1.1e-21 77.3 0.0 1.2e-21 77.1 0.0 1.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain N2227 PF07942.12 CRK34715.1 - 3.6e-34 118.2 0.0 4e-34 118.1 0.0 1.0 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.6 CRK34715.1 - 0.00031 20.6 0.0 0.00033 20.5 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CRK34715.1 - 0.014 16.0 0.0 0.022 15.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 CRK34715.1 - 0.037 14.8 0.0 0.065 14.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 CRK34715.1 - 0.068 12.3 0.0 0.16 11.1 0.0 1.6 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family Cep57_CLD_2 PF14197.6 CRK34717.1 - 0.00048 20.2 1.5 0.37 10.9 0.6 2.5 2 1 0 2 2 2 2 Centrosome localisation domain of PPC89 Laminin_II PF06009.12 CRK34717.1 - 0.00053 20.0 0.4 0.0017 18.4 0.1 1.7 1 1 1 2 2 2 1 Laminin Domain II TPR_MLP1_2 PF07926.12 CRK34717.1 - 0.0033 17.5 2.1 0.0057 16.7 1.9 1.6 1 1 0 1 1 1 1 TPR/MLP1/MLP2-like protein Phage_GP20 PF06810.11 CRK34717.1 - 0.0076 16.1 0.5 0.016 15.0 0.5 1.4 1 1 0 1 1 1 1 Phage minor structural protein GP20 ATG16 PF08614.11 CRK34717.1 - 0.027 14.7 3.2 0.052 13.8 2.8 1.8 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 CRK34717.1 - 0.038 14.0 0.7 2 8.4 0.5 2.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.21 CRK34717.1 - 0.04 13.5 0.2 0.045 13.3 0.2 1.1 1 0 0 1 1 1 0 Intermediate filament protein baeRF_family11 PF18855.1 CRK34717.1 - 0.052 13.9 1.9 0.06 13.7 1.1 1.5 1 1 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 11 Troponin PF00992.20 CRK34717.1 - 0.061 13.6 0.1 0.074 13.3 0.1 1.2 1 0 0 1 1 1 0 Troponin SIKE PF05769.11 CRK34717.1 - 0.063 13.2 0.1 0.079 12.9 0.1 1.3 1 0 0 1 1 1 0 SIKE family ABC_tran_CTD PF16326.5 CRK34717.1 - 0.091 13.0 2.0 10 6.4 2.8 2.3 1 1 0 2 2 2 0 ABC transporter C-terminal domain Spc7 PF08317.11 CRK34717.1 - 0.22 10.4 1.1 0.26 10.1 1.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein CCDC144C PF14915.6 CRK34717.1 - 0.57 9.2 2.3 2.8 7.0 0.3 2.1 1 1 1 2 2 2 0 CCDC144C protein coiled-coil region Phosphorylase PF00343.20 CRK34718.1 - 6.1e-42 143.8 0.0 6.6e-42 143.7 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase CcmH PF03918.14 CRK34719.1 - 0.089 12.1 0.0 0.093 12.0 0.0 1.1 1 0 0 1 1 1 0 Cytochrome C biogenesis protein CMAS PF02353.20 CRK34721.1 - 9.2e-06 25.1 0.0 9.6e-06 25.1 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.6 CRK34721.1 - 0.00038 20.3 0.1 0.00047 20.0 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK34721.1 - 0.0029 18.3 0.1 0.0046 17.6 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CRK34721.1 - 0.0038 17.1 0.0 0.0039 17.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 CRK34721.1 - 0.0079 16.0 0.0 0.0087 15.8 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.12 CRK34721.1 - 0.021 15.5 0.0 0.036 14.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 CRK34721.1 - 0.024 14.2 0.0 0.026 14.1 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.18 CRK34721.1 - 0.067 12.5 0.0 0.076 12.3 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family IMPDH PF00478.25 CRK34723.1 - 7.8e-36 123.8 0.2 9.1e-36 123.6 0.2 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 CRK34723.1 - 1.6e-05 25.2 0.0 3.1e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 CBS domain YpsA PF06908.11 CRK34723.1 - 0.048 13.7 0.0 0.11 12.4 0.0 1.5 2 0 0 2 2 2 0 YspA SLOG family PK PF00224.21 CRK34723.1 - 0.078 11.9 0.0 0.35 9.7 0.0 1.8 1 1 0 2 2 2 0 Pyruvate kinase, barrel domain FAD_binding_6 PF00970.24 CRK34724.1 - 4.2e-07 30.2 0.0 6.5e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Glyco_hydro_3_C PF01915.22 CRK34725.1 - 1.1e-26 94.1 0.2 1.2e-26 94.0 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Peptidase_M28 PF04389.17 CRK34726.1 - 3.6e-06 26.8 0.0 4.5e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M28 His_Phos_2 PF00328.22 CRK34728.1 - 7.6e-33 114.4 0.1 8.5e-33 114.2 0.1 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DASH_Ask1 PF08655.10 CRK34728.1 - 0.056 13.3 0.0 0.09 12.7 0.0 1.3 1 0 0 1 1 1 0 DASH complex subunit Ask1 dsrm PF00035.26 CRK34732.1 - 0.0019 18.8 0.0 2.1 9.1 0.0 2.5 2 0 0 2 2 2 2 Double-stranded RNA binding motif DSPc PF00782.20 CRK34734.1 - 4.8e-24 84.7 0.0 4.3e-21 75.1 0.0 2.2 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CRK34734.1 - 0.012 15.2 0.0 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 CRK34734.1 - 0.059 13.7 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Rit1 DUSP-like domain UAA PF08449.11 CRK34735.1 - 1.3e-16 60.7 3.3 1.5e-16 60.5 3.3 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 CRK34735.1 - 7e-06 26.3 5.9 8.3e-06 26.0 5.9 1.1 1 0 0 1 1 1 1 EamA-like transporter family SdpI PF13630.6 CRK34735.1 - 5.1 7.3 7.0 0.48 10.6 0.7 2.1 1 1 1 2 2 2 0 SdpI/YhfL protein family KH_1 PF00013.29 CRK34736.1 - 1.1e-66 220.6 33.7 7e-15 54.6 0.1 6.3 5 1 1 6 6 6 6 KH domain UAA PF08449.11 CRK34736.1 - 4.2e-53 180.5 11.5 6.2e-43 147.1 4.9 2.2 2 0 0 2 2 2 2 UAA transporter family KH_2 PF07650.17 CRK34736.1 - 1.7e-13 50.2 26.1 0.12 12.2 0.3 6.4 6 0 0 6 6 6 6 KH domain KH_4 PF13083.6 CRK34736.1 - 5.2e-11 42.3 13.9 0.14 12.0 0.1 6.3 6 0 0 6 6 6 3 KH domain KH_5 PF13184.6 CRK34736.1 - 0.00027 20.9 18.2 1.9 8.6 0.1 6.1 6 0 0 6 6 6 2 NusA-like KH domain Nuc_sug_transp PF04142.15 CRK34736.1 - 0.0017 17.6 4.5 0.02 14.1 0.1 2.7 3 0 0 3 3 3 2 Nucleotide-sugar transporter dUTPase PF00692.19 CRK34736.1 - 0.2 11.3 2.2 27 4.4 0.0 3.4 4 0 0 4 4 4 0 dUTPase UPF0061 PF02696.14 CRK34736.1 - 0.52 9.0 9.5 2.6 6.7 1.4 2.1 2 0 0 2 2 2 0 Uncharacterized ACR, YdiU/UPF0061 family DEAD PF00270.29 CRK34737.1 - 1.6e-28 99.6 0.0 2.4e-28 99.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CRK34737.1 - 4.2e-08 33.4 0.0 2e-07 31.2 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CRK34737.1 - 0.00013 22.3 0.1 0.0033 17.8 0.0 2.7 2 1 1 3 3 3 1 Helicase conserved C-terminal domain PRAI PF00697.22 CRK34737.1 - 0.15 11.8 0.0 0.38 10.5 0.0 1.6 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase DEAD PF00270.29 CRK34739.1 - 2e-28 99.3 0.0 3.2e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CRK34739.1 - 2.8e-21 76.0 0.0 5.1e-20 71.9 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CRK34739.1 - 7.2e-08 32.6 0.0 3.2e-07 30.5 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1529 PF07485.11 CRK34739.1 - 0.016 15.1 0.0 0.44 10.5 0.0 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1259) PRAI PF00697.22 CRK34739.1 - 0.14 11.9 0.0 0.32 10.7 0.0 1.6 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase TIP41 PF04176.13 CRK34740.1 - 3.8e-70 234.8 0.2 4.6e-70 234.6 0.2 1.1 1 0 0 1 1 1 1 TIP41-like family CBF PF03914.17 CRK34741.1 - 4.2e-26 92.0 0.1 6.3e-26 91.4 0.1 1.3 1 0 0 1 1 1 1 CBF/Mak21 family AA_kinase PF00696.28 CRK34741.1 - 3.8e-19 69.2 0.9 6.5e-19 68.5 0.9 1.3 1 0 0 1 1 1 1 Amino acid kinase family DUF4690 PF15756.5 CRK34741.1 - 0.13 12.8 1.6 0.48 11.0 0.2 2.4 2 0 0 2 2 2 0 Small Novel Rich in Cartilage TIP41 PF04176.13 CRK34742.1 - 3.6e-70 234.9 0.2 4.4e-70 234.6 0.2 1.1 1 0 0 1 1 1 1 TIP41-like family Pkinase PF00069.25 CRK34743.1 - 1.3e-72 244.3 0.0 1.7e-72 244.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK34743.1 - 1.9e-43 148.6 0.0 2.6e-43 148.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CRK34743.1 - 1.5e-07 31.1 0.0 2.1e-06 27.3 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 CRK34743.1 - 0.00039 19.8 0.1 0.00071 19.0 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CRK34743.1 - 0.014 15.0 0.0 0.057 13.0 0.0 1.8 1 1 1 2 2 2 0 RIO1 family Haspin_kinase PF12330.8 CRK34743.1 - 0.043 12.7 4.5 0.19 10.6 0.0 2.1 2 0 0 2 2 2 0 Haspin like kinase domain YrbL-PhoP_reg PF10707.9 CRK34743.1 - 0.052 13.1 0.3 0.2 11.2 0.0 1.9 1 1 0 2 2 2 0 PhoP regulatory network protein YrbL FTA2 PF13095.6 CRK34743.1 - 0.072 12.7 0.0 0.21 11.2 0.0 1.7 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 CRK34743.1 - 0.1 12.5 0.1 0.2 11.6 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 CRK34743.1 - 0.13 11.3 0.0 0.25 10.4 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 CRK34743.1 - 0.56 8.9 2.1 0.87 8.3 2.0 1.4 1 1 0 1 1 1 0 Fungal protein kinase Peptidase_M76 PF09768.9 CRK34744.1 - 6.6e-63 211.5 2.6 1.2e-53 181.4 2.9 2.6 2 1 0 2 2 2 2 Peptidase M76 family Ribosomal_L40e PF01020.17 CRK34744.1 - 0.006 16.4 0.0 4.6 7.2 0.0 2.4 2 0 0 2 2 2 2 Ribosomal L40e family SprT-like PF10263.9 CRK34744.1 - 0.022 14.6 0.1 0.058 13.3 0.1 1.7 1 0 0 1 1 1 0 SprT-like family Peptidase_M91 PF14891.6 CRK34744.1 - 0.12 12.7 0.1 0.29 11.4 0.1 1.6 1 0 0 1 1 1 0 Effector protein YpzI PF14140.6 CRK34744.1 - 0.12 12.1 0.5 22 4.9 0.1 2.4 2 0 0 2 2 2 0 YpzI-like protein BssB_TutG PF18512.1 CRK34744.1 - 0.15 12.0 1.9 28 4.7 0.0 3.5 4 0 0 4 4 4 0 Benzylsuccinate synthase beta subunit Vps51 PF08700.11 CRK34744.1 - 0.17 12.0 0.0 16 5.7 0.0 2.3 2 0 0 2 2 2 0 Vps51/Vps67 PRIMA1 PF16101.5 CRK34744.1 - 1.2 9.2 9.7 5.9 7.0 1.2 2.4 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 AA_kinase PF00696.28 CRK34745.1 - 2.1e-36 125.7 1.3 3.2e-36 125.1 1.3 1.3 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 CRK34745.1 - 6.7e-14 51.6 0.1 2.1e-13 50.0 0.0 2.0 2 0 0 2 2 2 1 PUA domain UPF0113_N PF17833.1 CRK34746.1 - 1.3e-24 86.6 0.1 1.7e-24 86.1 0.1 1.2 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 CRK34746.1 - 6.8e-19 67.9 0.0 1.1e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 UPF0113 PUA domain UPF0113 PF03657.13 CRK34747.1 - 1.7e-18 66.6 0.0 3e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 UPF0113 PUA domain UPF0113_N PF17833.1 CRK34747.1 - 2.4e-10 40.8 0.0 3.6e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain NOC3p PF07540.11 CRK34748.1 - 3.3e-56 187.7 8.9 2.5e-27 95.1 1.2 3.4 2 0 0 2 2 2 2 Nucleolar complex-associated protein CBF PF03914.17 CRK34748.1 - 7.2e-25 88.0 0.1 7.2e-25 88.0 0.1 2.3 3 0 0 3 3 3 1 CBF/Mak21 family DUF1841 PF08897.11 CRK34748.1 - 0.0043 17.1 0.2 5.1 7.1 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF1841) CRAL_TRIO_N PF03765.15 CRK34748.1 - 0.021 15.0 6.4 2.4 8.4 0.0 3.5 4 0 0 4 4 4 0 CRAL/TRIO, N-terminal domain PIG-X PF08320.12 CRK34748.1 - 0.028 14.3 0.3 7.4 6.4 0.0 2.9 3 0 0 3 3 3 0 PIG-X / PBN1 DUF313 PF03754.13 CRK34748.1 - 1.4 9.1 9.0 11 6.3 1.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF313) DUF5340 PF17275.2 CRK34748.1 - 4.3 7.5 13.1 15 5.8 2.8 2.9 2 0 0 2 2 2 0 Family of unknown function (DUF5340) CCDC53 PF10152.9 CRK34748.1 - 6.4 7.2 8.1 0.91 9.9 0.0 3.4 3 0 0 3 3 3 0 Subunit CCDC53 of WASH complex DRIM PF07539.12 CRK34750.1 - 0.019 13.3 0.0 0.025 12.9 0.0 1.1 1 0 0 1 1 1 0 Down-regulated in metastasis RNase_P_pop3 PF08228.11 CRK34750.1 - 0.026 14.6 0.0 0.32 11.0 0.0 2.2 1 1 0 2 2 2 0 RNase P subunit Pop3 CRIM PF16978.5 CRK34751.1 - 2.1e-44 151.1 0.0 5.8e-44 149.7 0.0 1.8 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain UCH PF00443.29 CRK34751.1 - 2.1e-40 138.8 1.2 5e-40 137.6 1.2 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase SIN1_PH PF16979.5 CRK34751.1 - 2.2e-23 82.6 0.2 4.8e-23 81.5 0.2 1.5 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology UCH_1 PF13423.6 CRK34751.1 - 5.9e-19 68.8 1.1 1.2e-18 67.8 1.1 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase TUG-UBL1 PF11470.8 CRK34751.1 - 0.0034 17.6 0.0 0.01 16.1 0.0 1.7 1 0 0 1 1 1 1 TUG ubiquitin-like domain PH PF00169.29 CRK34751.1 - 0.068 13.7 0.0 0.16 12.5 0.0 1.6 1 0 0 1 1 1 0 PH domain PRCC PF10253.9 CRK34752.1 - 3.4e-36 126.0 15.5 3.4e-36 126.0 15.5 3.3 2 1 1 3 3 3 1 Mitotic checkpoint regulator, MAD2B-interacting Glyco_trans_2_3 PF13632.6 CRK34754.1 - 7.1e-46 156.6 1.7 1.9e-45 155.2 1.7 1.7 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 CRK34754.1 - 3.2e-06 27.1 0.1 2.5e-05 24.1 0.0 2.3 2 1 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 CRK34754.1 - 0.00024 20.6 0.0 0.00094 18.7 0.0 2.0 2 1 0 2 2 2 1 Glycosyl transferase family 21 Chitin_synth_2 PF03142.15 CRK34754.1 - 0.086 11.4 0.1 0.086 11.4 0.1 1.5 2 0 0 2 2 2 0 Chitin synthase Flavi_NS4A PF01350.17 CRK34754.1 - 0.13 12.2 0.3 0.34 10.8 0.3 1.7 1 0 0 1 1 1 0 Flavivirus non-structural protein NS4A IncE PF17627.2 CRK34754.1 - 0.34 10.9 2.7 0.75 9.8 2.7 1.5 1 0 0 1 1 1 0 Inclusion membrane protein E PI-PLC-Y PF00387.19 CRK34755.1 - 4.6e-37 126.9 0.1 6e-37 126.5 0.1 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 CRK34755.1 - 1.7e-05 25.0 0.0 2.8e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 C2 domain PI-PLC-X PF00388.19 CRK34756.1 - 1.9e-63 212.4 0.0 2.9e-63 211.8 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 CRK34756.1 - 2.1e-41 140.9 0.0 3.3e-41 140.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain TFIIA PF03153.13 CRK34757.1 - 0.14 12.2 25.3 0.16 12.0 25.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 CRK34757.1 - 0.32 11.6 20.7 0.46 11.1 20.7 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DivIC PF04977.15 CRK34757.1 - 0.43 10.4 8.1 0.65 9.8 8.1 1.2 1 0 0 1 1 1 0 Septum formation initiator Suf PF05843.14 CRK34757.1 - 0.47 10.4 16.1 0.52 10.2 16.1 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4820 PF16091.5 CRK34757.1 - 0.67 9.3 7.5 0.83 9.0 7.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) CDK2AP PF09806.9 CRK34757.1 - 0.71 9.9 14.9 0.93 9.5 14.9 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein ARS2 PF04959.13 CRK34757.1 - 1 9.7 8.1 1.3 9.4 8.1 1.2 1 0 0 1 1 1 0 Arsenite-resistance protein 2 Presenilin PF01080.17 CRK34757.1 - 1.4 7.6 11.5 1.4 7.6 11.5 1.0 1 0 0 1 1 1 0 Presenilin FAM60A PF15396.6 CRK34757.1 - 1.7 8.6 8.7 2 8.3 8.7 1.1 1 0 0 1 1 1 0 Protein Family FAM60A ASD2 PF08687.11 CRK34757.1 - 2 7.9 10.5 2.3 7.7 10.5 1.1 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 Hydin_ADK PF17213.3 CRK34757.1 - 2.1 8.6 11.2 2.8 8.2 11.2 1.2 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Zip PF02535.22 CRK34757.1 - 2.4 7.3 4.6 2.4 7.3 4.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter SLC12 PF03522.15 CRK34757.1 - 2.4 7.1 7.7 2.6 7.0 7.7 1.0 1 0 0 1 1 1 0 Solute carrier family 12 SMYLE_N PF18615.1 CRK34757.1 - 2.5 7.6 8.6 3 7.3 8.6 1.0 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Neur_chan_memb PF02932.16 CRK34757.1 - 3.1 7.8 8.0 3.5 7.6 8.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MAJIN PF15077.6 CRK34757.1 - 3.1 7.5 9.6 3.5 7.4 9.6 1.0 1 0 0 1 1 1 0 Membrane-anchored junction protein Hid1 PF12722.7 CRK34757.1 - 4.7 5.2 11.3 5.1 5.1 11.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Peroxin-3 PF04882.12 CRK34757.1 - 5.9 5.8 16.2 6.9 5.5 16.2 1.0 1 0 0 1 1 1 0 Peroxin-3 CorA PF01544.18 CRK34758.1 - 0.0036 16.7 4.0 0.0041 16.5 2.8 1.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF983 PF06170.12 CRK34758.1 - 0.39 11.2 3.0 1.5 9.3 3.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF983) Lectin_leg-like PF03388.13 CRK34759.1 - 5.4e-65 219.0 0.0 6.9e-65 218.6 0.0 1.0 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 CRK34759.1 - 2.3e-08 34.3 0.0 3.2e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 CRK34759.1 - 6.9e-06 25.8 0.0 0.0059 16.2 0.0 2.2 2 0 0 2 2 2 2 Legume lectin domain ATG27 PF09451.10 CRK34759.1 - 0.097 12.5 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Autophagy-related protein 27 zf-Tim10_DDP PF02953.15 CRK34760.1 - 7.1e-23 80.0 2.1 8.8e-23 79.7 2.1 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF2116 PF09889.9 CRK34760.1 - 0.2 11.7 1.8 0.24 11.4 0.2 1.9 1 1 1 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) LMBR1 PF04791.16 CRK34761.1 - 3.5e-107 359.4 8.4 4.1e-107 359.2 8.4 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein NmrA PF05368.13 CRK34762.1 - 1.1e-08 34.9 0.0 0.0039 16.8 0.0 2.1 2 0 0 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.6 CRK34762.1 - 1.3e-07 31.7 0.0 2.3e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 CRK34762.1 - 0.0053 16.2 0.0 0.0096 15.4 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 CRK34762.1 - 0.022 14.2 0.0 0.039 13.4 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase RmlD_sub_bind PF04321.17 CRK34762.1 - 0.053 12.6 0.0 0.081 12.0 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Iso_dh PF00180.20 CRK34763.1 - 5e-126 420.5 0.0 6.8e-126 420.1 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PI-PLC-X PF00388.19 CRK34763.1 - 1.9e-25 89.2 0.0 3.6e-25 88.2 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Raftlin PF15250.6 CRK34763.1 - 1 8.0 2.5 0.67 8.6 0.1 1.8 2 0 0 2 2 2 0 Raftlin Pkinase PF00069.25 CRK34764.1 - 2.8e-74 249.8 0.0 3.8e-74 249.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK34764.1 - 1.1e-37 129.8 0.0 1.6e-37 129.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CRK34764.1 - 7.3e-07 28.8 0.1 1.7e-06 27.5 0.0 1.7 2 0 0 2 2 2 1 Kinase-like TFIIA PF03153.13 CRK34764.1 - 1.9 8.4 34.3 2.4 8.0 34.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CorA PF01544.18 CRK34765.1 - 0.0036 16.7 4.0 0.0041 16.5 2.8 1.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF983 PF06170.12 CRK34765.1 - 0.39 11.2 3.0 1.5 9.3 3.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF983) Lectin_leg-like PF03388.13 CRK34766.1 - 1.1e-64 217.9 0.0 1.5e-64 217.5 0.0 1.0 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 CRK34766.1 - 2.9e-08 34.0 0.0 4.4e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 CRK34766.1 - 3.6e-06 26.7 0.0 0.027 14.0 0.0 2.2 2 0 0 2 2 2 2 Legume lectin domain ATG27 PF09451.10 CRK34766.1 - 0.035 13.9 0.0 0.042 13.7 0.0 1.2 1 0 0 1 1 1 0 Autophagy-related protein 27 zf-Tim10_DDP PF02953.15 CRK34767.1 - 7.1e-23 80.0 2.1 8.8e-23 79.7 2.1 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF2116 PF09889.9 CRK34767.1 - 0.2 11.7 1.8 0.24 11.4 0.2 1.9 1 1 1 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) LMBR1 PF04791.16 CRK34768.1 - 2.7e-97 326.8 10.4 2.7e-97 326.8 10.4 2.5 2 1 0 2 2 2 1 LMBR1-like membrane protein DUF2040 PF09745.9 CRK34768.1 - 3.5e-33 114.2 10.2 3.5e-33 114.2 10.2 4.1 3 2 0 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) DTHCT PF08070.11 CRK34768.1 - 0.014 16.1 0.1 0.014 16.1 0.1 4.7 5 0 0 5 5 5 0 DTHCT (NUC029) region NmrA PF05368.13 CRK34769.1 - 3.2e-16 59.6 0.0 3.9e-16 59.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 CRK34769.1 - 1.4e-09 38.1 0.0 2.2e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 CRK34769.1 - 0.0012 18.3 0.0 0.0025 17.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 CRK34769.1 - 0.12 11.8 0.0 0.41 10.1 0.0 1.8 2 0 0 2 2 2 0 short chain dehydrogenase Iso_dh PF00180.20 CRK34771.1 - 1.8e-126 422.0 0.0 2.6e-126 421.5 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF4451 PF14616.6 CRK34772.1 - 2.8e-05 24.3 0.5 6.1e-05 23.2 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) AflR PF08493.10 CRK34772.1 - 2.4 7.6 10.8 2.9 7.3 10.8 1.1 1 0 0 1 1 1 0 Aflatoxin regulatory protein MFS_1 PF07690.16 CRK34775.1 - 2e-19 69.8 37.1 1.8e-09 37.0 11.4 3.4 3 0 0 3 3 3 3 Major Facilitator Superfamily Actin PF00022.19 CRK34775.1 - 3.3e-14 52.3 0.0 1.6e-07 30.3 0.0 2.1 2 0 0 2 2 2 2 Actin MFS_1_like PF12832.7 CRK34775.1 - 0.059 12.2 5.2 0.84 8.4 0.0 2.7 3 0 0 3 3 3 0 MFS_1 like family Actin_micro PF17003.5 CRK34775.1 - 0.34 10.1 0.1 0.5 9.5 0.1 1.2 1 0 0 1 1 1 0 Putative actin-like family DUF4451 PF14616.6 CRK34776.1 - 3.1e-24 85.5 0.1 5.3e-24 84.7 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) Stm1_N PF09598.10 CRK34776.1 - 6e-11 43.0 2.4 6e-11 43.0 2.4 3.7 3 1 0 3 3 3 1 Stm1 Actin PF00022.19 CRK34778.1 - 7.5e-26 90.7 0.0 1.8e-16 59.8 0.0 2.5 2 1 0 2 2 2 2 Actin MFS_1 PF07690.16 CRK34778.1 - 1.9e-17 63.2 39.6 1.5e-08 33.9 13.1 3.3 3 0 0 3 3 3 3 Major Facilitator Superfamily Actin_micro PF17003.5 CRK34778.1 - 0.0011 18.2 0.9 0.66 9.1 0.1 2.2 2 0 0 2 2 2 2 Putative actin-like family MreB_Mbl PF06723.13 CRK34778.1 - 0.011 14.6 0.0 0.6 8.9 0.0 2.2 2 0 0 2 2 2 0 MreB/Mbl protein FtsA PF14450.6 CRK34778.1 - 0.016 15.6 0.0 0.058 13.8 0.0 2.0 1 1 0 1 1 1 0 Cell division protein FtsA MFS_1_like PF12832.7 CRK34778.1 - 0.022 13.7 1.3 2.3 7.0 0.0 2.6 2 1 1 3 3 3 0 MFS_1 like family bZIP_1 PF00170.21 CRK34780.1 - 6.9e-06 26.1 6.6 6.9e-06 26.1 6.6 1.7 2 0 0 2 2 2 1 bZIP transcription factor ComFB PF10719.9 CRK34780.1 - 0.21 11.7 1.5 0.43 10.7 1.5 1.4 1 0 0 1 1 1 0 Late competence development protein ComFB DUF5595 PF18077.1 CRK34780.1 - 0.22 11.6 0.8 0.34 11.0 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) GvpL_GvpF PF06386.11 CRK34780.1 - 0.72 9.7 4.5 1.1 9.1 4.5 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF bZIP_2 PF07716.15 CRK34780.1 - 1.6 8.8 10.0 0.64 10.1 6.4 2.2 2 0 0 2 2 2 0 Basic region leucine zipper DUF4407 PF14362.6 CRK34780.1 - 5 6.4 6.2 12 5.1 6.5 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Med10 PF09748.9 CRK34781.1 - 2.4e-43 147.0 0.0 4.6e-43 146.0 0.0 1.5 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF2027 PF09640.10 CRK34781.1 - 0.19 11.3 0.0 0.34 10.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2027) TPR_1 PF00515.28 CRK34782.1 - 1.5e-42 141.7 10.9 1e-08 34.6 0.1 7.9 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.17 CRK34782.1 - 1.6e-37 124.6 13.3 6.4e-07 29.0 0.0 7.9 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_11 PF13414.6 CRK34782.1 - 2.5e-27 94.3 13.8 2.3e-07 30.4 0.1 7.1 5 2 3 8 8 7 5 TPR repeat DnaJ PF00226.31 CRK34782.1 - 3.5e-26 91.1 5.3 1.4e-25 89.2 5.3 2.1 1 0 0 1 1 1 1 DnaJ domain TPR_16 PF13432.6 CRK34782.1 - 2.6e-23 82.4 3.4 0.00011 22.8 0.0 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 CRK34782.1 - 6.1e-21 74.7 12.1 7.6e-07 29.6 0.0 6.3 3 3 2 5 5 5 5 Tetratricopeptide repeat TPR_8 PF13181.6 CRK34782.1 - 3.5e-20 70.5 11.5 0.00088 19.3 0.1 7.1 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_17 PF13431.6 CRK34782.1 - 9.2e-17 60.1 13.9 0.019 15.3 0.0 7.1 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 CRK34782.1 - 1.5e-15 56.6 14.0 0.00055 20.5 0.0 7.7 4 2 4 8 8 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 CRK34782.1 - 2.3e-15 56.6 17.0 0.00012 22.3 0.3 7.3 4 4 4 8 8 8 4 Tetratricopeptide repeat ANAPC3 PF12895.7 CRK34782.1 - 1.1e-14 54.4 5.1 2.1e-07 31.0 0.1 4.2 3 1 0 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 CRK34782.1 - 2.6e-14 52.1 4.4 0.16 12.1 0.0 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_9 PF13371.6 CRK34782.1 - 3.2e-12 46.4 7.7 0.03 14.5 0.1 5.0 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_15 PF13429.6 CRK34782.1 - 4.7e-08 32.6 11.4 0.028 13.6 0.1 4.4 2 2 0 3 3 3 3 Tetratricopeptide repeat TPR_6 PF13174.6 CRK34782.1 - 2.7e-06 27.7 14.5 1.1 10.1 0.0 7.3 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_10 PF13374.6 CRK34782.1 - 3.7e-06 26.6 14.2 0.051 13.5 1.6 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_4 PF07721.14 CRK34782.1 - 0.00011 22.4 0.1 1.7 9.5 0.0 4.4 4 0 0 4 4 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CRK34782.1 - 0.00099 19.1 2.8 2.3 8.3 0.2 4.2 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.6 CRK34782.1 - 0.0012 19.1 9.2 0.91 9.9 0.0 4.7 3 2 2 5 5 5 2 Tetratricopeptide repeat Coatomer_E PF04733.14 CRK34782.1 - 0.0042 16.5 4.8 0.033 13.6 0.1 3.0 3 0 0 3 3 3 1 Coatomer epsilon subunit Alkyl_sulf_dimr PF14863.6 CRK34782.1 - 0.0066 16.9 2.8 1.7 9.1 0.0 3.9 2 1 2 4 4 4 1 Alkyl sulfatase dimerisation BTAD PF03704.17 CRK34782.1 - 0.022 15.2 7.8 5.8 7.3 0.1 4.4 2 2 3 5 5 4 0 Bacterial transcriptional activator domain ChAPs PF09295.10 CRK34782.1 - 0.1 11.5 0.1 0.29 10.1 0.0 1.7 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) DUF357 PF04010.13 CRK34782.1 - 3.3 7.9 6.1 3.4 7.8 0.3 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF357) EF-hand_6 PF13405.6 CRK34783.1 - 1.3e-11 43.4 0.7 2.2e-05 24.0 0.2 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 CRK34783.1 - 8.4e-09 34.4 1.9 0.0031 17.0 0.2 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CRK34783.1 - 1.3e-06 28.7 2.4 5.5e-05 23.5 0.6 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CRK34783.1 - 1.5e-05 24.2 3.9 0.0031 16.9 0.4 2.5 2 0 0 2 2 2 2 EF hand Amidohydro_2 PF04909.14 CRK34783.1 - 4.8e-05 23.3 0.0 9.6e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase EF-hand_8 PF13833.6 CRK34783.1 - 0.00013 21.7 0.2 0.11 12.4 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 CRK34783.1 - 0.0043 17.4 0.0 1.6 9.1 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain CoA_binding_2 PF13380.6 CRK34783.1 - 0.061 13.8 0.0 0.18 12.3 0.0 1.8 1 0 0 1 1 1 0 CoA binding domain DUF3708 PF12501.8 CRK34783.1 - 0.15 11.9 0.1 0.52 10.1 0.1 1.8 1 1 1 2 2 2 0 Phosphate ATP-binding cassette transporter bZIP_1 PF00170.21 CRK34784.1 - 6.8e-06 26.1 6.6 6.8e-06 26.1 6.6 1.7 2 0 0 2 2 2 1 bZIP transcription factor ComFB PF10719.9 CRK34784.1 - 0.21 11.7 1.5 0.43 10.7 1.5 1.4 1 0 0 1 1 1 0 Late competence development protein ComFB DUF5595 PF18077.1 CRK34784.1 - 0.22 11.6 0.8 0.34 11.0 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) GvpL_GvpF PF06386.11 CRK34784.1 - 0.73 9.7 4.5 1.1 9.1 4.5 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF bZIP_2 PF07716.15 CRK34784.1 - 1.6 8.8 10.0 0.64 10.2 6.4 2.2 2 0 0 2 2 2 0 Basic region leucine zipper DUF4407 PF14362.6 CRK34784.1 - 6.4 6.0 6.4 19 4.5 7.1 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Med10 PF09748.9 CRK34786.1 - 5.6e-81 268.4 0.4 8.8e-45 151.6 0.1 2.5 1 1 1 2 2 2 2 Transcription factor subunit Med10 of Mediator complex Phage_lysis PF03245.13 CRK34786.1 - 0.034 14.3 0.2 0.092 12.9 0.2 1.8 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein DUF3877 PF12993.7 CRK34786.1 - 0.21 11.4 0.0 22 4.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3877) TPR_1 PF00515.28 CRK34789.1 - 3.6e-31 105.7 6.3 6.8e-07 28.8 0.6 5.6 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_2 PF07719.17 CRK34789.1 - 3.6e-30 101.6 7.1 5.8e-07 29.1 0.0 5.9 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.6 CRK34789.1 - 4.1e-24 84.0 8.5 2.1e-07 30.5 0.1 5.3 4 1 2 6 6 5 4 TPR repeat TPR_16 PF13432.6 CRK34789.1 - 1.5e-18 67.2 2.6 0.00011 22.8 0.0 4.6 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.6 CRK34789.1 - 5.2e-16 57.4 3.9 0.0088 16.2 0.2 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 CRK34789.1 - 7.9e-15 55.1 8.1 5.7e-07 30.0 0.0 5.2 3 2 1 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.6 CRK34789.1 - 1.2e-14 53.7 3.9 0.0005 20.7 0.0 5.6 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 CRK34789.1 - 1.6e-13 50.7 8.6 6.9e-05 23.1 0.3 5.3 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 CRK34789.1 - 3.4e-13 48.6 1.3 0.078 13.0 0.0 5.2 5 0 0 5 5 5 4 Tetratricopeptide repeat ANAPC3 PF12895.7 CRK34789.1 - 1e-12 48.1 1.1 5.2e-08 33.0 0.1 3.2 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 CRK34789.1 - 1.8e-11 43.5 10.2 0.012 15.9 0.0 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_9 PF13371.6 CRK34789.1 - 2.9e-09 36.9 3.7 0.026 14.7 0.1 3.8 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_15 PF13429.6 CRK34789.1 - 4.7e-07 29.3 3.7 0.021 14.0 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 CRK34789.1 - 3.1e-06 27.4 6.4 0.88 10.3 0.0 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_10 PF13374.6 CRK34789.1 - 6.1e-06 25.9 7.4 0.046 13.6 1.6 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_20 PF14561.6 CRK34789.1 - 0.00052 20.3 0.6 1.6 9.1 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_4 PF07721.14 CRK34789.1 - 0.00069 20.0 3.3 1.6 9.6 0.0 4.9 5 0 0 5 5 3 1 Tetratricopeptide repeat Coatomer_E PF04733.14 CRK34789.1 - 0.0055 16.2 0.2 0.033 13.6 0.0 2.2 2 0 0 2 2 2 1 Coatomer epsilon subunit DnaJ PF00226.31 CRK34789.1 - 0.0088 16.2 0.9 0.022 14.9 0.2 2.1 2 0 0 2 2 1 1 DnaJ domain BTAD PF03704.17 CRK34789.1 - 0.028 14.8 2.8 3.7 8.0 0.1 3.6 2 2 2 4 4 4 0 Bacterial transcriptional activator domain Alkyl_sulf_dimr PF14863.6 CRK34789.1 - 0.054 14.0 1.2 1.7 9.1 0.1 2.9 2 1 0 2 2 2 0 Alkyl sulfatase dimerisation Fis1_TPR_C PF14853.6 CRK34789.1 - 0.08 13.0 1.1 3.3 7.9 0.1 3.2 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat ChAPs PF09295.10 CRK34789.1 - 0.11 11.5 0.1 0.23 10.4 0.0 1.5 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPM_phosphatase PF04536.14 CRK34789.1 - 0.46 10.7 2.2 9.4 6.4 0.2 3.0 2 1 1 3 3 3 0 TPM domain DUF357 PF04010.13 CRK34789.1 - 0.77 9.9 2.9 3.1 8.0 0.3 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF357) Chorion_2 PF03964.15 CRK34789.1 - 2 9.3 12.9 0.18 12.7 4.4 3.6 3 1 0 3 3 2 0 Chorion family 2 EF-hand_6 PF13405.6 CRK34790.1 - 1.5e-11 43.2 0.7 2.6e-05 23.8 0.2 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 CRK34790.1 - 1.7e-09 36.5 1.4 0.00083 18.7 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CRK34790.1 - 3.4e-06 27.4 2.4 9.2e-05 22.8 0.6 2.3 1 1 1 2 2 2 2 EF-hand domain pair Amidohydro_2 PF04909.14 CRK34790.1 - 2e-05 24.5 0.0 4.2e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase EF-hand_8 PF13833.6 CRK34790.1 - 2.3e-05 24.1 0.1 0.018 14.9 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 CRK34790.1 - 5.2e-05 22.6 3.9 0.01 15.3 0.4 2.5 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.6 CRK34790.1 - 0.0092 16.3 0.0 3.5 8.0 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain Esterase PF00756.20 CRK34791.1 - 2.1e-09 37.4 0.0 2.6e-09 37.1 0.0 1.0 1 0 0 1 1 1 1 Putative esterase SPA PF08616.10 CRK34792.1 - 6.5e-37 126.0 0.0 9.9e-37 125.4 0.0 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 CRK34792.1 - 0.017 13.8 0.0 0.18 10.4 0.0 2.1 1 1 1 2 2 2 0 Transport protein Avl9 DUF2347 PF09804.9 CRK34792.1 - 0.029 13.9 0.0 0.061 12.9 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) Peripla_BP_6 PF13458.6 CRK34792.1 - 0.1 12.3 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein Methyltransf_PK PF05891.12 CRK34792.1 - 0.11 11.9 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Esterase PF00756.20 CRK34793.1 - 1.3e-46 159.3 0.0 2e-46 158.7 0.0 1.3 1 0 0 1 1 1 1 Putative esterase RNA_pol_Rpb6 PF01192.22 CRK34793.1 - 1.1e-16 60.5 0.2 1.9e-16 59.7 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb6 Esterase_phd PF10503.9 CRK34793.1 - 5.9e-05 22.7 0.0 0.00022 20.8 0.0 1.9 1 1 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 CRK34793.1 - 0.0015 18.0 0.0 0.005 16.3 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 CRK34793.1 - 0.013 14.8 0.0 0.026 13.8 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 CRK34793.1 - 0.039 12.9 0.0 0.089 11.7 0.0 1.5 1 0 0 1 1 1 0 Chlorophyllase enzyme HTH_Tnp_Tc5 PF03221.16 CRK34793.1 - 0.092 12.8 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain Abhydrolase_6 PF12697.7 CRK34793.1 - 0.11 13.1 0.0 0.26 11.9 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family zf-C2H2 PF00096.26 CRK34794.1 - 6.9e-25 86.1 57.0 0.00053 20.3 0.1 10.4 10 0 0 10 10 10 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CRK34794.1 - 7.2e-16 57.5 59.5 0.095 13.6 0.2 10.8 11 0 0 11 11 11 8 C2H2-type zinc finger FOXP-CC PF16159.5 CRK34794.1 - 5.4e-09 36.6 33.4 0.0006 20.4 0.4 8.0 6 2 2 8 8 8 3 FOXP coiled-coil domain zf-met PF12874.7 CRK34794.1 - 4.9e-07 29.9 19.3 0.32 11.4 0.0 7.8 9 0 0 9 9 8 2 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 CRK34794.1 - 2.3e-06 27.8 19.8 0.0021 18.3 4.9 5.3 3 2 2 5 5 5 2 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 CRK34794.1 - 3.7e-06 27.1 32.5 1.8 8.9 1.4 9.1 11 0 0 11 11 10 4 Zinc-finger double-stranded RNA-binding zf-C2H2_aberr PF17017.5 CRK34794.1 - 6.1e-06 26.5 14.0 0.077 13.1 1.8 4.6 3 1 0 4 4 4 3 Aberrant zinc-finger zf-H2C2_2 PF13465.6 CRK34794.1 - 1.9e-05 24.9 63.4 0.005 17.2 0.9 11.1 12 1 0 12 12 11 4 Zinc-finger double domain DUF4187 PF13821.6 CRK34794.1 - 0.038 13.8 2.7 0.095 12.5 0.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) zf_Hakai PF18408.1 CRK34794.1 - 0.51 10.1 0.0 0.51 10.1 0.0 8.0 10 0 0 10 10 10 0 C2H2 Hakai zinc finger domain zf_ZIC PF18366.1 CRK34794.1 - 0.98 9.6 0.0 0.98 9.6 0.0 6.3 8 0 0 8 8 8 0 Zic proteins zinc finger domain zf_CopZ PF18423.1 CRK34794.1 - 5.4 7.0 6.9 12 5.9 0.2 3.8 3 1 1 4 4 4 0 Zinc binding domain Zip PF02535.22 CRK34795.1 - 6.4e-14 51.9 5.9 7.1e-11 41.9 0.3 2.2 2 0 0 2 2 2 2 ZIP Zinc transporter Endonuclease_NS PF01223.23 CRK34796.1 - 7.2e-46 156.8 0.0 8.9e-46 156.5 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease YbgS PF13985.6 CRK34796.1 - 0.15 12.3 0.6 0.23 11.8 0.6 1.3 1 0 0 1 1 1 0 YbgS-like protein Stomoxyn PF11585.8 CRK34796.1 - 0.32 11.1 2.3 0.52 10.4 2.3 1.4 1 0 0 1 1 1 0 Insect antimicrobial peptide, stomoxyn Glyco_hydro_18 PF00704.28 CRK34808.1 - 1.5e-36 126.8 0.4 1.7e-36 126.5 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Alk_phosphatase PF00245.20 CRK34810.1 - 5.7e-23 81.5 0.0 6.3e-23 81.4 0.0 1.0 1 0 0 1 1 1 1 Alkaline phosphatase DUF5577 PF17740.1 CRK34810.1 - 0.15 11.7 0.0 0.18 11.5 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5577) DIM1 PF02966.16 CRK34811.1 - 2.4e-48 163.3 0.4 2.7e-48 163.1 0.4 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 PQQ_2 PF13360.6 CRK34812.1 - 0.11 12.0 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 PQQ-like domain CortBP2 PF09727.9 CRK34816.1 - 0.0075 16.2 2.3 0.013 15.4 2.3 1.3 1 0 0 1 1 1 1 Cortactin-binding protein-2 Pedibin PF08182.11 CRK34816.1 - 0.045 13.5 4.4 0.14 12.0 4.4 1.8 1 0 0 1 1 1 0 Pedibin/Hym-346 family NDUFA12 PF05071.16 CRK34817.1 - 4.4e-14 53.1 0.7 7e-14 52.4 0.7 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Ank_2 PF12796.7 CRK34817.1 - 5.5e-10 39.7 0.1 1e-08 35.7 0.0 2.7 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 CRK34817.1 - 2.9e-08 33.8 7.1 0.009 16.4 1.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 CRK34817.1 - 1.5e-07 31.2 4.3 0.2 12.3 0.1 4.8 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.6 CRK34817.1 - 2.5e-07 31.1 1.9 0.00051 20.5 0.3 4.1 1 1 2 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 CRK34817.1 - 6.7e-06 26.3 2.3 0.0029 17.9 0.2 3.6 2 1 2 4 4 4 1 Ankyrin repeats (many copies) Herpes_BMRF2 PF04633.12 CRK34820.1 - 0.18 11.0 0.0 0.22 10.7 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus BMRF2 protein TPP_enzyme_C PF02775.21 CRK34821.1 - 1.2e-37 129.1 0.0 1.3e-37 129.0 0.0 1.0 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain LysM PF01476.20 CRK34824.1 - 1.9e-15 56.6 5.1 0.00045 20.2 0.0 5.4 6 0 0 6 6 6 4 LysM domain Glyco_hydro_18 PF00704.28 CRK34825.1 - 1.4e-67 228.7 2.2 2.3e-67 227.9 2.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 CRK34825.1 - 1.4e-10 41.5 15.5 1.4e-10 41.5 15.5 4.4 5 0 0 5 5 5 1 Chitin recognition protein GMC_oxred_N PF00732.19 CRK34827.1 - 6.7e-66 222.7 0.0 8e-66 222.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 CRK34827.1 - 0.0003 19.9 2.2 0.00039 19.6 0.6 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 CRK34827.1 - 0.0014 17.8 0.5 0.11 11.5 0.8 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 CRK34827.1 - 0.0095 15.2 1.5 0.011 15.0 0.1 1.7 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 CRK34827.1 - 0.16 12.6 0.7 9.7 6.8 0.4 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pribosyltran PF00156.27 CRK34828.1 - 5.5e-07 29.2 0.0 1.2e-06 28.1 0.0 1.5 1 1 0 1 1 1 1 Phosphoribosyl transferase domain TPR_14 PF13428.6 CRK34831.1 - 0.063 14.1 0.6 15 6.7 0.1 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 CRK34831.1 - 0.13 12.1 1.0 0.52 10.2 0.2 2.3 2 1 0 2 2 2 0 Tetratricopeptide repeat Miga PF10265.9 CRK34831.1 - 0.13 11.2 0.0 0.14 11.2 0.0 1.0 1 0 0 1 1 1 0 Mitoguardin Clathrin PF00637.20 CRK34835.1 - 2.7e-23 82.4 0.8 3.1e-23 82.2 0.8 1.0 1 0 0 1 1 1 1 Region in Clathrin and VPS NB PF04159.13 CRK34835.1 - 0.13 12.3 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 NB glycoprotein DPPIV_N PF00930.21 CRK34836.1 - 7.1e-54 182.9 1.9 8.5e-54 182.6 1.9 1.1 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region zf-C2H2 PF00096.26 CRK34836.1 - 0.41 11.2 1.1 0.64 10.6 0.3 1.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type PRMT5_C PF17286.2 CRK34837.1 - 1.6e-19 70.5 0.0 1.8e-19 70.3 0.0 1.0 1 0 0 1 1 1 1 PRMT5 oligomerisation domain YtxH PF12732.7 CRK34837.1 - 0.56 10.8 0.0 0.56 10.8 0.0 1.8 2 0 0 2 2 2 0 YtxH-like protein zf-CCCH_3 PF15663.5 CRK34841.1 - 0.79 10.0 7.7 1 9.6 7.7 1.4 1 1 0 1 1 1 0 Zinc-finger containing family NYN PF01936.18 CRK34845.1 - 1.5e-22 80.6 0.0 1.7e-22 80.5 0.0 1.0 1 0 0 1 1 1 1 NYN domain Peripla_BP_1 PF00532.21 CRK34845.1 - 0.065 12.6 0.0 0.074 12.5 0.0 1.1 1 0 0 1 1 1 0 Periplasmic binding proteins and sugar binding domain of LacI family AMP-binding PF00501.28 CRK34846.1 - 1.2e-14 53.8 0.0 1.8e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme EF_TS PF00889.19 CRK34846.1 - 0.043 13.4 0.0 0.12 11.9 0.0 1.7 1 1 0 1 1 1 0 Elongation factor TS PQ-loop PF04193.14 CRK34851.1 - 0.00032 20.4 0.0 0.00051 19.8 0.0 1.3 1 0 0 1 1 1 1 PQ loop repeat Presenilin PF01080.17 CRK34851.1 - 0.024 13.4 0.6 0.026 13.3 0.6 1.2 1 0 0 1 1 1 0 Presenilin CCDC106 PF15794.5 CRK34851.1 - 0.064 13.0 9.4 0.084 12.6 9.4 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 RR_TM4-6 PF06459.12 CRK34851.1 - 0.7 9.7 6.3 0.9 9.3 6.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Apt1 PF10351.9 CRK34851.1 - 1.2 7.9 7.0 1.3 7.7 7.0 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain BshC PF10079.9 CRK34854.1 - 0.01 14.6 2.1 0.011 14.5 2.1 1.0 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC Annexin_like PF18411.1 CRK34854.1 - 0.026 14.8 0.1 0.037 14.3 0.1 1.2 1 0 0 1 1 1 0 Annexin-like domain OmpH PF03938.14 CRK34854.1 - 0.05 13.9 2.6 0.06 13.7 2.6 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) TraF PF13728.6 CRK34854.1 - 0.087 12.6 1.7 0.11 12.3 1.7 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein BLOC1_2 PF10046.9 CRK34854.1 - 0.088 13.1 2.0 0.14 12.5 2.0 1.4 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Rb_C PF08934.10 CRK34854.1 - 0.12 12.1 0.6 0.15 11.9 0.6 1.1 1 0 0 1 1 1 0 Rb C-terminal domain Histidinol_dh PF00815.20 CRK34854.1 - 0.15 11.0 0.7 0.17 10.9 0.7 1.1 1 0 0 1 1 1 0 Histidinol dehydrogenase p450 PF00067.22 CRK34862.1 - 0.027 13.2 0.0 0.029 13.1 0.0 1.0 1 0 0 1 1 1 0 Cytochrome P450 Peptidase_M28 PF04389.17 CRK34867.1 - 1.2e-16 61.0 0.0 1.4e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 CRK34867.1 - 0.064 13.0 0.0 0.064 13.0 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Ferric_reduct PF01794.19 CRK34868.1 - 3.3e-07 30.4 4.3 5.7e-07 29.7 4.3 1.5 1 0 0 1 1 1 1 Ferric reductase like transmembrane component UDPG_MGDP_dh PF00984.19 CRK34872.1 - 1.5e-19 69.9 0.0 4.5e-19 68.5 0.0 1.8 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_N PF03721.14 CRK34872.1 - 1.2e-15 57.6 0.0 3e-13 49.8 0.0 2.3 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.15 CRK34872.1 - 3.5e-06 27.3 0.0 6.6e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_C PF03720.15 CRK34872.1 - 5.8e-05 23.5 0.0 0.00012 22.5 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain TrkA_N PF02254.18 CRK34872.1 - 0.033 14.4 0.0 0.079 13.2 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Polysacc_deac_1 PF01522.21 CRK34873.1 - 9.5e-16 57.8 0.2 2.6e-15 56.4 0.2 1.9 1 1 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 CRK34873.1 - 8.4e-07 29.4 59.3 5.8e-05 23.5 18.5 3.0 3 0 0 3 3 3 2 Chitin recognition protein DUF2334 PF10096.9 CRK34873.1 - 0.19 11.3 0.0 0.4 10.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) Chitin_synth_2 PF03142.15 CRK34874.1 - 4.8e-40 137.7 6.8 2.5e-31 108.9 5.1 2.3 1 1 1 2 2 2 2 Chitin synthase Glycos_transf_2 PF00535.26 CRK34874.1 - 9.3e-07 28.8 0.0 0.034 13.9 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 CRK34874.1 - 3.6e-05 23.8 3.7 3.6e-05 23.8 3.7 3.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 CRK34874.1 - 0.0012 18.8 0.1 3 7.7 0.0 2.9 3 0 0 3 3 3 2 Glycosyltransferase like family 2 AzlD PF05437.12 CRK34874.1 - 0.028 14.6 0.0 0.028 14.6 0.0 2.7 3 1 0 3 3 3 0 Branched-chain amino acid transport protein (AzlD) DcuA_DcuB PF03605.14 CRK34874.1 - 0.043 12.7 0.9 0.51 9.2 0.1 2.1 2 0 0 2 2 2 0 Anaerobic c4-dicarboxylate membrane transporter DUF2418 PF10332.9 CRK34874.1 - 8.7 6.9 6.9 4.1 8.0 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2418) Polysacc_deac_1 PF01522.21 CRK34875.1 - 1.2e-28 99.5 0.0 2.1e-28 98.7 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 CRK34875.1 - 5.8e-06 26.7 13.9 1.1e-05 25.7 13.9 1.5 1 0 0 1 1 1 1 Chitin recognition protein Glyco_hydro_57 PF03065.15 CRK34875.1 - 0.00094 18.5 0.0 0.0019 17.5 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 57 DUF2334 PF10096.9 CRK34875.1 - 0.051 13.2 0.0 0.075 12.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) Sec34 PF04136.15 CRK34876.1 - 0.096 12.6 0.1 0.15 11.9 0.1 1.2 1 0 0 1 1 1 0 Sec34-like family COG6 PF06419.11 CRK34876.1 - 0.16 10.2 0.3 0.25 9.5 0.1 1.4 2 0 0 2 2 2 0 Conserved oligomeric complex COG6 4HBT_3 PF13622.6 CRK34878.1 - 1.4e-21 77.9 1.3 1.5e-21 77.8 1.3 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 CRK34878.1 - 1.3e-09 38.0 0.0 0.0015 18.3 0.0 2.1 2 0 0 2 2 2 2 Acyl-CoA thioesterase 7tm_2 PF00002.24 CRK34879.1 - 5.1e-05 22.7 1.3 5.1e-05 22.7 1.3 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Haemocyan_bet_s PF14830.6 CRK34879.1 - 0.12 12.4 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Haemocyanin beta-sandwich CBFD_NFYB_HMF PF00808.23 CRK34880.1 - 8.1e-13 48.5 2.1 8.1e-13 48.5 2.1 1.9 2 1 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Thymidylat_synt PF00303.19 CRK34881.1 - 1.1e-35 123.1 0.0 1.2e-35 123.0 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase PHO4 PF01384.20 CRK34882.1 - 3.8e-101 338.5 13.8 4.8e-101 338.2 13.8 1.1 1 0 0 1 1 1 1 Phosphate transporter family F-box-like PF12937.7 CRK34882.1 - 3.2e-05 23.7 0.0 0.00011 22.0 0.0 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CRK34882.1 - 0.0033 17.3 0.0 0.0083 16.0 0.0 1.6 1 0 0 1 1 1 1 F-box domain UPF0444 PF15475.6 CRK34882.1 - 6.5 7.1 9.2 5.2 7.4 0.3 2.8 2 0 0 2 2 2 0 Transmembrane protein C12orf23, UPF0444 Band_7 PF01145.25 CRK34883.1 - 5.8e-15 55.8 0.0 5.8e-15 55.8 0.0 3.2 3 2 0 3 3 3 1 SPFH domain / Band 7 family Glyco_hydro_3_C PF01915.22 CRK34884.1 - 3.5e-47 161.0 0.0 5.4e-47 160.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 CRK34884.1 - 5.7e-35 121.2 0.0 9.8e-35 120.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 CRK34884.1 - 1e-20 73.6 0.0 2e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain TPR_2 PF07719.17 CRK34887.1 - 5.3e-07 29.3 1.4 0.00011 22.0 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 CRK34887.1 - 8.6e-05 22.5 0.0 0.001 19.1 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 CRK34887.1 - 0.0002 21.9 1.2 0.00044 20.8 1.1 1.7 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 CRK34887.1 - 0.00076 19.7 1.1 0.002 18.4 1.1 1.7 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 CRK34887.1 - 0.0011 19.4 0.1 0.0041 17.6 0.1 1.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 CRK34887.1 - 0.0027 17.5 0.2 0.041 13.7 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_4 PF07721.14 CRK34887.1 - 0.02 15.4 9.6 0.045 14.4 3.0 3.1 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 CRK34887.1 - 0.06 14.2 0.9 0.06 14.2 0.9 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 CRK34887.1 - 0.062 14.0 0.6 0.37 11.5 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 CRK34887.1 - 0.46 10.7 4.3 0.44 10.7 0.8 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat FDF PF09532.10 CRK34890.1 - 3.6e-10 40.7 0.6 5.7e-10 40.0 0.6 1.3 1 0 0 1 1 1 1 FDF domain zf_C2H2_ZHX PF18387.1 CRK34890.1 - 0.044 13.4 0.0 8.1 6.2 0.0 2.2 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain Sugar_tr PF00083.24 CRK34893.1 - 1.4e-20 73.6 3.1 1.4e-20 73.6 3.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK34893.1 - 7.1e-08 31.8 8.5 7.6e-08 31.7 8.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 CRK34893.1 - 0.00059 18.5 2.9 0.00066 18.4 2.9 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein DUF5518 PF17647.1 CRK34893.1 - 0.013 15.7 3.5 0.018 15.2 3.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5518) MFS_1_like PF12832.7 CRK34893.1 - 0.014 14.3 1.6 0.014 14.3 1.6 1.0 1 0 0 1 1 1 0 MFS_1 like family SOG2 PF10428.9 CRK34894.1 - 5.1 6.2 9.3 10 5.2 9.3 1.5 1 0 0 1 1 1 0 RAM signalling pathway protein NmrA PF05368.13 CRK34895.1 - 4.7e-79 265.2 0.0 6.3e-79 264.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Fungal_trans PF04082.18 CRK34895.1 - 1e-14 54.2 2.7 1.3e-14 53.9 1.7 1.6 1 1 1 2 2 2 1 Fungal specific transcription factor domain NAD_binding_10 PF13460.6 CRK34895.1 - 2.8e-06 27.3 0.1 7.2e-05 22.8 0.1 2.2 1 1 0 1 1 1 1 NAD(P)H-binding Zn_clus PF00172.18 CRK34895.1 - 5.7e-06 26.4 11.8 8.7e-06 25.8 11.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EXOSC1 PF10447.9 CRK34896.1 - 6.9e-18 65.3 2.4 3.5e-13 50.1 0.1 2.8 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 Sec2p PF06428.11 CRK34896.1 - 3.9e-12 46.0 5.2 3.9e-12 46.0 5.2 2.8 2 1 1 3 3 3 1 GDP/GTP exchange factor Sec2p ECR1_N PF14382.6 CRK34896.1 - 2.1e-08 33.8 0.8 4.2e-08 32.9 0.8 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region CCDC53 PF10152.9 CRK34896.1 - 0.026 14.9 0.6 0.026 14.9 0.6 2.3 2 1 0 2 2 2 0 Subunit CCDC53 of WASH complex Jnk-SapK_ap_N PF09744.9 CRK34896.1 - 0.038 14.2 15.7 0.31 11.3 9.8 2.3 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 SlyX PF04102.12 CRK34896.1 - 0.14 12.7 20.4 0.35 11.5 4.1 3.8 2 2 1 3 3 3 0 SlyX DUF4795 PF16043.5 CRK34896.1 - 0.15 11.6 3.9 1.3 8.6 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) Exonuc_VII_L PF02601.15 CRK34896.1 - 0.21 11.1 8.7 0.29 10.6 5.0 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit Atg14 PF10186.9 CRK34896.1 - 0.73 8.9 8.0 8 5.5 0.0 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF16 PF01519.16 CRK34896.1 - 1 9.9 3.3 23 5.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF16 HAUS-augmin3 PF14932.6 CRK34896.1 - 1.1 8.7 10.5 0.31 10.6 3.8 2.3 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 DivIC PF04977.15 CRK34896.1 - 1.2 8.9 9.6 0.98 9.2 1.8 2.9 2 1 0 2 2 2 0 Septum formation initiator Mod_r PF07200.13 CRK34896.1 - 9.4 6.3 12.1 4.4 7.4 1.5 2.2 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein ERG2_Sigma1R PF04622.12 CRK34897.1 - 4.2e-93 310.5 0.5 4.9e-93 310.3 0.5 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein TruB_N PF01509.18 CRK34898.1 - 1.2e-43 149.1 0.0 2.4e-43 148.1 0.0 1.5 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 CRK34898.1 - 7e-06 26.1 0.0 1.4e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain GAGA_bind PF06217.12 CRK34898.1 - 6.2 7.0 13.3 3.5 7.8 4.7 2.2 2 0 0 2 2 2 0 GAGA binding protein-like family DNMT1-RFD PF12047.8 CRK34900.1 - 0.00038 20.5 0.0 0.001 19.1 0.0 1.7 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain AsnC_trans_reg2 PF17805.1 CRK34900.1 - 0.018 15.2 0.1 0.049 13.8 0.1 1.7 1 0 0 1 1 1 0 AsnC-like ligand binding domain MKT1_C PF12246.8 CRK34901.1 - 9.1e-50 169.1 0.0 7.7e-49 166.1 0.0 2.1 1 1 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 CRK34901.1 - 5.2e-29 100.4 0.1 1.1e-28 99.4 0.1 1.6 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.17 CRK34901.1 - 0.001 19.5 0.0 0.0024 18.3 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain DIOX_N PF14226.6 CRK34902.1 - 7.9e-22 78.2 0.0 1.3e-21 77.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 CRK34902.1 - 5.6e-13 49.2 0.0 1.1e-12 48.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DNA_ligase_A_N PF04675.14 CRK34903.1 - 4.3e-23 82.5 0.0 9e-23 81.5 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_M PF01068.21 CRK34903.1 - 6.3e-22 78.2 0.0 1.7e-21 76.8 0.0 1.7 1 0 0 1 1 1 1 ATP dependent DNA ligase domain RNA_ligase PF09414.10 CRK34903.1 - 2.8e-08 34.3 0.0 8.8e-08 32.6 0.0 1.9 1 0 0 1 1 1 1 RNA ligase Spt20 PF12090.8 CRK34903.1 - 0.13 11.9 11.3 0.32 10.6 11.3 1.6 1 0 0 1 1 1 0 Spt20 family FAD-SLDH PF12318.8 CRK34903.1 - 0.13 12.3 2.3 0.28 11.2 2.3 1.5 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase GBP PF02263.19 CRK34903.1 - 0.25 10.6 2.1 2.2 7.5 0.5 2.3 2 0 0 2 2 2 0 Guanylate-binding protein, N-terminal domain TFIIA PF03153.13 CRK34903.1 - 1.2 9.1 12.7 0.046 13.7 2.7 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit ATP-synt_ab PF00006.25 CRK34904.1 - 2.9e-105 350.6 0.0 4.2e-105 350.1 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 CRK34904.1 - 1.1e-47 160.8 0.0 5.3e-46 155.4 0.0 2.5 2 0 0 2 2 2 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 CRK34904.1 - 8.8e-14 51.8 3.8 2.1e-13 50.6 3.8 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF4048 PF13257.6 CRK34904.1 - 1.5e-13 51.2 1.6 1.5e-13 51.2 1.6 4.6 3 1 2 5 5 5 2 Domain of unknown function (DUF4048) LPD23 PF18838.1 CRK34904.1 - 0.15 11.9 0.1 0.4 10.5 0.1 1.7 1 0 0 1 1 1 0 Large polyvalent protein associated domain 23 Ferritin_2 PF13668.6 CRK34905.1 - 4e-39 133.9 0.3 6.3e-39 133.3 0.3 1.3 1 0 0 1 1 1 1 Ferritin-like domain LIME1 PF15332.6 CRK34905.1 - 0.16 11.5 0.8 0.29 10.7 0.8 1.4 1 0 0 1 1 1 0 Lck-interacting transmembrane adapter 1 Metallophos PF00149.28 CRK34906.1 - 0.00029 21.4 0.0 0.0022 18.6 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Ferritin_2 PF13668.6 CRK34907.1 - 4.1e-28 98.3 1.1 1.9e-19 70.2 0.2 2.3 1 1 1 2 2 2 2 Ferritin-like domain RNB PF00773.19 CRK34908.1 - 8.4e-79 265.2 0.0 1.4e-78 264.5 0.0 1.4 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 CRK34908.1 - 1.5e-26 92.2 0.1 1.1e-25 89.4 0.0 2.4 2 0 0 2 2 2 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 CRK34908.1 - 1.4e-25 89.4 0.0 4.8e-25 87.7 0.0 2.0 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal CSD2 PF17876.1 CRK34908.1 - 0.0048 17.0 0.0 0.012 15.8 0.0 1.7 1 0 0 1 1 1 1 Cold shock domain CHASE5 PF17149.4 CRK34908.1 - 0.11 12.4 0.0 2.9 7.9 0.0 2.5 2 0 0 2 2 2 0 Periplasmic sensor domain found in signal transduction proteins DUF4239 PF14023.6 CRK34908.1 - 0.14 11.9 0.2 0.28 10.9 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) Rrp44_S1 PF17215.3 CRK34908.1 - 0.16 12.0 0.0 0.53 10.3 0.0 1.9 1 0 0 1 1 1 0 S1 domain DUF4355 PF14265.6 CRK34908.1 - 1.2 9.3 8.9 0.083 13.1 3.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) GLE1 PF07817.13 CRK34909.1 - 2.6e-12 46.5 0.0 4e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 GLE1-like protein THOC7 PF05615.13 CRK34909.1 - 0.02 15.2 10.2 0.02 15.2 10.2 2.0 2 0 0 2 2 2 0 Tho complex subunit 7 RNB PF00773.19 CRK34910.1 - 3.9e-78 263.0 0.0 7.1e-78 262.2 0.0 1.5 1 0 0 1 1 1 1 RNB domain Dis3l2_C_term PF17877.1 CRK34910.1 - 1.3e-25 89.5 0.0 4.3e-25 87.9 0.0 2.0 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal Syntaxin-6_N PF09177.11 CRK34910.1 - 6.2e-23 81.2 0.1 6.2e-23 81.2 0.1 3.3 3 0 0 3 3 3 1 Syntaxin 6, N-terminal OB_Dis3 PF17849.1 CRK34910.1 - 1.5e-22 79.4 0.0 6.6e-22 77.3 0.0 2.1 2 0 0 2 2 2 1 Dis3-like cold-shock domain 2 (CSD2) CSD2 PF17876.1 CRK34910.1 - 0.039 14.1 0.0 0.087 13.0 0.0 1.6 1 0 0 1 1 1 0 Cold shock domain GLE1 PF07817.13 CRK34912.1 - 4e-63 212.9 0.0 5.5e-63 212.5 0.0 1.2 1 0 0 1 1 1 1 GLE1-like protein TSA PF03249.13 CRK34912.1 - 0.3 9.8 2.1 0.55 9.0 2.1 1.4 1 0 0 1 1 1 0 Type specific antigen THOC7 PF05615.13 CRK34912.1 - 0.6 10.4 16.9 0.08 13.2 11.8 2.0 2 0 0 2 2 2 0 Tho complex subunit 7 Ndc1_Nup PF09531.10 CRK34912.1 - 8.3 5.0 7.0 13 4.3 7.0 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Syntaxin-6_N PF09177.11 CRK34913.1 - 1.1e-24 86.8 0.8 4e-24 85.0 0.1 2.0 2 0 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 CRK34913.1 - 0.00063 19.7 1.7 0.0013 18.7 1.7 1.6 1 0 0 1 1 1 1 SNARE domain DUF3348 PF11828.8 CRK34913.1 - 0.016 14.9 0.7 0.024 14.3 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3348) BLOC1_2 PF10046.9 CRK34913.1 - 0.13 12.5 0.9 0.97 9.8 0.2 2.3 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.12 CRK34913.1 - 0.28 11.7 1.5 26 5.4 0.3 2.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein TBCA PF02970.16 CRK34913.1 - 0.39 11.1 3.2 0.66 10.3 1.2 2.3 2 1 0 2 2 2 0 Tubulin binding cofactor A ATG16 PF08614.11 CRK34913.1 - 1.2 9.4 9.4 3.5 7.8 1.5 2.8 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Methyltransf_32 PF13679.6 CRK34914.1 - 5e-21 75.3 0.1 1.5e-20 73.8 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain eIF3_subunit PF08597.10 CRK34914.1 - 0.14 12.1 3.4 0.2 11.5 2.4 1.7 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit Methyltransf_32 PF13679.6 CRK34915.1 - 1.1e-21 77.5 0.2 1.9e-21 76.7 0.2 1.4 1 0 0 1 1 1 1 Methyltransferase domain ACT_7 PF13840.6 CRK34916.1 - 1.7e-23 82.2 0.1 3.2e-17 62.1 0.0 2.4 2 0 0 2 2 2 2 ACT domain UPF0029 PF01205.19 CRK34917.1 - 1e-32 112.6 0.1 1.6e-32 111.9 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 CRK34917.1 - 4e-05 23.9 0.0 6.1e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 RWD domain Herpes_capsid PF06112.11 CRK34917.1 - 2 8.4 10.8 4.2 7.4 10.8 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein FAT PF02259.23 CRK34918.1 - 1.1e-69 235.3 6.6 3.6e-69 233.6 6.6 2.0 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 CRK34918.1 - 2.8e-13 50.3 1.6 4.5e-13 49.6 0.2 2.2 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 CRK34918.1 - 3.4e-08 33.2 0.2 9.8e-08 31.7 0.2 1.9 1 0 0 1 1 1 1 FATC domain TPR_8 PF13181.6 CRK34918.1 - 0.021 15.0 3.6 0.058 13.6 0.2 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA_32 PF13654.6 CRK34918.1 - 0.028 13.2 0.5 0.094 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain TPR_2 PF07719.17 CRK34918.1 - 0.069 13.3 5.2 4.9 7.5 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 CRK34918.1 - 0.14 12.1 2.8 14 5.7 0.2 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat GGACT PF06094.12 CRK34919.1 - 1.2e-19 71.1 0.0 1.5e-19 70.8 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like DUF4932 PF16286.5 CRK34919.1 - 0.0022 17.3 0.0 0.0028 17.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4932) Mito_carr PF00153.27 CRK34920.1 - 2.8e-36 123.3 4.0 3e-19 68.7 0.0 3.6 4 0 0 4 4 4 2 Mitochondrial carrier protein MFS_1 PF07690.16 CRK34920.1 - 6.5e-24 84.5 14.3 1.2e-23 83.7 14.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 CRK34920.1 - 6.8e-08 32.2 4.3 1.3e-07 31.3 4.3 1.4 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB PT-VENN PF04829.13 CRK34920.1 - 0.084 13.0 4.6 0.97 9.6 0.0 3.7 4 0 0 4 4 4 0 Pre-toxin domain with VENN motif Tim17 PF02466.19 CRK34920.1 - 0.24 11.8 9.8 0.84 10.0 0.3 3.4 3 1 1 4 4 4 0 Tim17/Tim22/Tim23/Pmp24 family Zn_clus PF00172.18 CRK34921.1 - 2.4e-11 43.6 9.5 2.4e-11 43.6 9.5 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2318 PF10080.9 CRK34921.1 - 0.045 13.9 4.3 1.9 8.6 3.9 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) HMG_CoA_synt_N PF01154.17 CRK34922.1 - 3.5e-95 316.8 0.2 4.3e-95 316.5 0.2 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 CRK34922.1 - 4.4e-26 92.1 0.3 6.4e-26 91.6 0.3 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal Glyco_hydro_61 PF03443.14 CRK34924.1 - 0.052 13.5 0.0 0.086 12.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 61 DUF3433 PF11915.8 CRK34925.1 - 5.7e-38 129.3 18.9 3e-21 75.7 1.4 3.8 5 0 0 5 5 5 2 Protein of unknown function (DUF3433) Tannase PF07519.11 CRK34926.1 - 0.19 10.6 0.0 0.27 10.1 0.0 1.2 1 0 0 1 1 1 0 Tannase and feruloyl esterase Ribosomal_L4 PF00573.22 CRK34927.1 - 2.5e-33 115.4 0.3 3.7e-33 114.8 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 CRK34927.1 - 1.3e-27 95.6 1.6 1.3e-27 95.6 1.6 1.9 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain T5orf172 PF10544.9 CRK34928.1 - 0.001 19.6 1.8 0.0016 19.0 1.8 1.3 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 CRK34928.1 - 0.12 13.0 1.0 0.21 12.3 1.0 1.4 1 0 0 1 1 1 0 Meiotically up-regulated gene 113 PrpF PF04303.13 CRK34929.1 - 7.1e-82 275.3 2.9 8.4e-75 252.0 3.6 2.0 2 0 0 2 2 2 2 PrpF protein Glyco_hydro_61 PF03443.14 CRK34931.1 - 0.045 13.7 0.0 0.073 13.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 61 DUF3433 PF11915.8 CRK34932.1 - 6.5e-27 93.8 15.6 2.1e-16 60.1 2.8 4.1 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) SRR1 PF07985.12 CRK34932.1 - 0.16 12.1 0.0 19 5.4 0.0 2.7 2 0 0 2 2 2 0 SRR1 Aminotran_1_2 PF00155.21 CRK34933.1 - 1.9e-05 24.0 0.0 5.9e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class I and II Ribosomal_L4 PF00573.22 CRK34934.1 - 2.5e-33 115.4 0.3 3.7e-33 114.8 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 CRK34934.1 - 1.3e-27 95.6 1.6 1.3e-27 95.6 1.6 1.9 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain T5orf172 PF10544.9 CRK34935.1 - 0.0036 17.8 2.0 0.016 15.8 2.0 2.1 1 0 0 1 1 1 1 T5orf172 domain ZZ PF00569.17 CRK34935.1 - 3.1 7.7 6.2 5.2 7.0 2.4 2.5 2 0 0 2 2 2 0 Zinc finger, ZZ type PGA2 PF07543.12 CRK34936.1 - 1.1e-35 122.6 0.8 1.3e-35 122.3 0.8 1.1 1 0 0 1 1 1 1 Protein trafficking PGA2 CENP-S PF15630.6 CRK34937.1 - 6.4e-27 93.7 0.0 1.4e-26 92.7 0.0 1.5 1 1 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 CRK34937.1 - 4.2e-06 26.8 0.1 5e-06 26.6 0.1 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold WD40 PF00400.32 CRK34939.1 - 7e-52 172.3 18.6 8.3e-07 29.6 0.0 11.3 10 1 0 10 10 10 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK34939.1 - 3.5e-13 49.7 5.5 0.0081 16.4 0.0 8.6 6 3 4 10 10 10 5 Anaphase-promoting complex subunit 4 WD40 domain Utp13 PF08625.11 CRK34939.1 - 1.7e-09 37.7 0.0 3e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nucleoporin_N PF08801.11 CRK34939.1 - 2.1e-07 30.1 1.2 2.1 7.0 0.0 5.7 3 3 1 5 5 5 4 Nup133 N terminal like Nup160 PF11715.8 CRK34939.1 - 1.1e-06 27.7 0.2 3.6 6.1 0.0 5.0 3 2 1 5 5 5 3 Nucleoporin Nup120/160 WD40_like PF17005.5 CRK34939.1 - 0.0015 17.9 0.0 8.5 5.6 0.0 4.3 4 0 0 4 4 4 1 WD40-like domain NmrA PF05368.13 CRK34940.1 - 4.7e-22 78.7 0.1 5.8e-22 78.4 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 CRK34940.1 - 3.7e-18 66.1 0.1 5.2e-18 65.6 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding DapB_N PF01113.20 CRK34940.1 - 1.2e-06 28.6 0.5 2.3e-06 27.7 0.5 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Sacchrp_dh_NADP PF03435.18 CRK34940.1 - 2.2e-06 28.0 0.0 5.3e-06 26.7 0.0 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 CRK34940.1 - 5.4e-05 22.8 0.1 0.00031 20.3 0.1 2.2 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 CRK34940.1 - 0.02 15.3 0.2 0.08 13.4 0.2 2.1 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 CRK34940.1 - 0.021 14.9 0.0 0.036 14.1 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase SF1-HH PF16275.5 CRK34941.1 - 0.012 15.9 0.2 0.032 14.6 0.2 1.7 1 0 0 1 1 1 0 Splicing factor 1 helix-hairpin domain WD40 PF00400.32 CRK34942.1 - 1.8e-36 123.5 17.9 4.9e-07 30.3 0.0 9.2 10 0 0 10 10 10 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK34942.1 - 3e-13 49.9 2.1 0.0084 16.4 0.0 7.0 4 3 4 8 8 8 5 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 CRK34942.1 - 2.3e-05 23.3 0.2 2.7 6.7 0.0 4.2 3 2 1 4 4 4 3 Nup133 N terminal like Nup160 PF11715.8 CRK34942.1 - 5.5e-05 22.0 0.1 2.4 6.7 0.0 4.0 2 1 2 4 4 4 3 Nucleoporin Nup120/160 eIF2A PF08662.11 CRK34942.1 - 0.16 11.8 0.1 8.3 6.2 0.0 3.1 3 1 1 4 4 4 0 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 CRK34942.1 - 0.27 10.5 0.0 44 3.3 0.0 3.2 3 0 0 3 3 3 0 WD40-like domain MFS_1 PF07690.16 CRK34943.1 - 1.5e-31 109.6 52.1 3.4e-31 108.5 52.1 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 CRK34943.1 - 1.8e-15 56.4 24.2 2.3e-15 56.0 24.2 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 CRK34943.1 - 1.1e-12 47.6 17.5 1.1e-12 47.6 17.5 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter DUF4337 PF14235.6 CRK34943.1 - 3.7 7.7 15.6 0.15 12.2 1.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4337) IF4E PF01652.18 CRK34944.1 - 3.6e-39 134.1 0.1 4.4e-39 133.8 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Utp13 PF08625.11 CRK34945.1 - 1.6e-53 180.4 0.6 2.3e-53 179.9 0.6 1.2 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain WD40 PF00400.32 CRK34945.1 - 4.9e-16 58.8 3.0 0.00048 20.9 0.0 4.3 4 1 0 4 4 4 3 WD domain, G-beta repeat Nucleoporin_N PF08801.11 CRK34945.1 - 0.0035 16.1 0.4 0.38 9.5 0.4 2.4 1 1 1 2 2 2 2 Nup133 N terminal like TPR_2 PF07719.17 CRK34946.1 - 8.7e-25 84.8 15.6 0.0005 20.0 0.4 10.1 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_1 PF00515.28 CRK34946.1 - 9.5e-24 82.2 14.6 3.6e-05 23.4 1.1 9.2 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_12 PF13424.6 CRK34946.1 - 6.2e-17 61.7 17.9 3.9e-08 33.5 0.1 8.0 5 1 3 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.6 CRK34946.1 - 3.1e-15 55.0 7.5 0.006 16.7 0.4 8.7 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 CRK34946.1 - 8.7e-15 55.0 15.6 0.096 13.2 0.0 7.1 6 2 1 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.6 CRK34946.1 - 6.5e-12 45.2 16.7 0.28 12.1 0.0 9.0 4 1 3 8 8 8 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CRK34946.1 - 9.1e-12 45.0 16.7 1.2e-05 25.4 0.2 7.5 4 3 5 9 9 9 2 Anaphase-promoting complex, cyclosome, subunit 3 zf-UBP PF02148.19 CRK34946.1 - 2.3e-11 43.8 0.3 5.5e-11 42.6 0.3 1.6 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH PF00443.29 CRK34946.1 - 1.4e-10 41.1 0.1 2.5e-10 40.3 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase TPR_10 PF13374.6 CRK34946.1 - 3.1e-10 39.6 7.2 0.00063 19.5 0.8 6.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 CRK34946.1 - 7.4e-10 39.3 17.1 4.4e-06 27.2 0.2 7.5 7 2 1 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.6 CRK34946.1 - 5.8e-06 26.0 11.4 0.79 9.9 0.2 7.7 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_11 PF13414.6 CRK34946.1 - 0.00019 21.1 11.8 0.73 9.6 0.1 5.9 6 1 1 7 7 7 3 TPR repeat TPR_9 PF13371.6 CRK34946.1 - 0.00024 21.2 6.0 0.014 15.5 0.7 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 CRK34946.1 - 0.00043 20.7 16.2 0.52 11.1 0.2 7.7 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_15 PF13429.6 CRK34946.1 - 0.0034 16.6 4.9 0.53 9.5 0.1 3.9 3 2 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 CRK34946.1 - 0.012 15.9 2.0 14 6.4 0.0 5.7 7 0 0 7 7 6 0 Tetratricopeptide repeat DUF1064 PF06356.11 CRK34946.1 - 0.051 13.9 0.1 0.13 12.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1064) UCH_1 PF13423.6 CRK34946.1 - 0.09 12.3 0.1 0.18 11.4 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase SNAP PF14938.6 CRK34946.1 - 0.26 10.7 6.0 7.2 5.9 0.0 3.1 3 0 0 3 3 3 0 Soluble NSF attachment protein, SNAP Fis1_TPR_C PF14853.6 CRK34946.1 - 4.9 7.3 7.3 26 5.0 0.2 3.9 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_21 PF09976.9 CRK34946.1 - 8.2 6.1 7.2 4 7.1 0.6 3.4 5 0 0 5 5 5 0 Tetratricopeptide repeat-like domain Glyco_hydro_16 PF00722.21 CRK34949.1 - 9.7e-08 31.7 0.0 1.3e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 CRK34949.1 - 8.1e-06 24.5 1.1 0.016 13.7 1.2 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) AMP-binding PF00501.28 CRK34950.1 - 1.4e-42 145.8 0.0 2.6e-42 144.9 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 CRK34950.1 - 0.00028 20.7 0.1 0.0006 19.7 0.1 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Malic_M PF03949.15 CRK34951.1 - 3e-93 311.8 0.0 4e-93 311.4 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 CRK34951.1 - 1.4e-63 214.0 0.0 2.9e-63 213.0 0.0 1.6 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain PadR PF03551.14 CRK34951.1 - 0.014 15.4 0.2 0.12 12.4 0.0 2.3 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family NmrA PF05368.13 CRK34952.1 - 1.7e-16 60.5 0.0 2.4e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 CRK34952.1 - 1.6e-09 37.9 0.0 3.2e-09 36.9 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 CRK34952.1 - 0.00034 21.1 0.0 0.00067 20.1 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 CRK34952.1 - 0.064 13.4 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus GAS2 PF02187.17 CRK34953.1 - 1.2e-06 28.5 0.0 2.5e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain FMO-like PF00743.19 CRK34954.1 - 8.2e-40 136.7 0.0 1.7e-23 82.9 0.0 3.0 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 CRK34954.1 - 5.1e-16 58.8 0.1 1.9e-10 40.5 0.1 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CRK34954.1 - 1.2e-14 54.3 0.0 1.1e-13 51.1 0.0 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CRK34954.1 - 3.4e-14 52.8 0.1 1.1e-11 44.5 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 CRK34954.1 - 1.5e-12 47.8 1.1 5e-10 39.6 0.1 3.9 3 2 1 4 4 4 1 FAD-NAD(P)-binding DAO PF01266.24 CRK34954.1 - 2e-10 40.8 0.3 0.00041 20.0 0.0 4.3 3 1 0 4 4 4 2 FAD dependent oxidoreductase Thi4 PF01946.17 CRK34954.1 - 1.9e-08 33.9 0.0 0.0002 20.7 0.0 2.4 2 0 0 2 2 2 2 Thi4 family NAD_binding_8 PF13450.6 CRK34954.1 - 7.1e-08 32.6 0.2 5.2e-07 29.8 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 CRK34954.1 - 3e-06 27.7 0.7 0.06 13.9 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CRK34954.1 - 1.6e-05 23.8 0.2 0.069 11.8 0.1 2.9 3 0 0 3 3 3 2 HI0933-like protein Amino_oxidase PF01593.24 CRK34954.1 - 4e-05 23.1 0.0 0.016 14.5 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase 2-Hacid_dh_C PF02826.19 CRK34954.1 - 0.0003 20.2 0.0 0.011 15.2 0.0 2.2 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 CRK34954.1 - 0.00045 19.6 0.6 0.083 12.1 0.0 2.6 3 0 0 3 3 3 1 FAD binding domain NAD_binding_7 PF13241.6 CRK34954.1 - 0.0059 17.0 0.1 3.5 8.1 0.0 2.4 2 1 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 CRK34954.1 - 0.0071 16.4 0.0 3.3 7.8 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 CRK34954.1 - 0.016 14.5 0.8 1.4 8.1 0.1 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 CRK34954.1 - 0.018 14.1 0.2 4.4 6.2 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein IlvN PF07991.12 CRK34954.1 - 0.018 14.6 0.0 1.7 8.2 0.0 2.4 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain FAD_binding_2 PF00890.24 CRK34954.1 - 0.043 12.9 0.2 0.9 8.5 0.0 2.6 3 0 0 3 3 3 0 FAD binding domain GIDA PF01134.22 CRK34954.1 - 0.13 11.4 0.6 4.7 6.2 0.1 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A TrkA_N PF02254.18 CRK34954.1 - 0.18 12.1 0.3 2.2 8.6 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain POT1 PF02765.17 CRK34955.1 - 1e-11 44.8 0.0 3.1e-11 43.3 0.0 1.8 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 Fungal_trans PF04082.18 CRK34957.1 - 1.3e-31 109.6 0.1 1.3e-31 109.6 0.1 2.7 2 1 1 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK34957.1 - 5.7e-08 32.8 9.6 1e-07 31.9 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2-Hacid_dh_C PF02826.19 CRK34959.1 - 2.6e-50 170.2 0.0 4.9e-50 169.4 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CRK34959.1 - 1.1e-15 57.5 0.0 1.6e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 CRK34959.1 - 0.00055 20.1 0.0 0.0012 19.1 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AA_permease_2 PF13520.6 CRK34960.1 - 8.3e-63 212.7 40.9 1.6e-62 211.7 40.9 1.4 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CRK34960.1 - 2.4e-27 95.7 28.0 2.4e-27 95.7 28.0 2.1 2 0 0 2 2 2 1 Amino acid permease DUF1754 PF08555.10 CRK34961.1 - 3.3e-14 53.5 18.2 6.4e-14 52.5 18.2 1.4 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) KI67R PF08065.12 CRK34961.1 - 0.065 13.8 13.1 5.2 7.7 10.3 2.1 1 1 1 2 2 2 0 KI67R (NUC007) repeat CDC27 PF09507.10 CRK34961.1 - 0.26 10.6 19.4 0.3 10.4 19.4 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 NOA36 PF06524.12 CRK34961.1 - 0.3 10.4 5.8 0.36 10.1 5.8 1.2 1 0 0 1 1 1 0 NOA36 protein RR_TM4-6 PF06459.12 CRK34961.1 - 1.2 8.9 13.2 1.4 8.6 13.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ORC2 PF04084.14 CRK34963.1 - 7.1e-119 396.6 0.0 8.6e-119 396.3 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 NTP_transf_3 PF12804.7 CRK34963.1 - 0.049 14.0 1.0 0.13 12.6 0.3 1.9 1 1 1 2 2 2 0 MobA-like NTP transferase domain CutC PF03932.14 CRK34966.1 - 1.9e-35 122.2 0.0 5.3e-35 120.7 0.0 1.6 1 1 0 1 1 1 1 CutC family FMN_dh PF01070.18 CRK34966.1 - 0.029 13.4 0.5 0.058 12.4 0.5 1.4 1 0 0 1 1 1 0 FMN-dependent dehydrogenase BtpA PF03437.15 CRK34966.1 - 0.07 12.5 0.2 0.25 10.8 0.0 1.8 2 0 0 2 2 2 0 BtpA family LCCL PF03815.19 CRK34968.1 - 1.9e-20 72.8 0.3 3.1e-20 72.1 0.3 1.3 1 0 0 1 1 1 1 LCCL domain TIP39 PF14980.6 CRK34968.1 - 0.12 12.3 0.1 3.5 7.6 0.0 2.5 2 0 0 2 2 2 0 TIP39 peptide Alk_phosphatase PF00245.20 CRK34970.1 - 1.7e-69 234.8 0.0 3.9e-69 233.6 0.0 1.5 1 1 0 1 1 1 1 Alkaline phosphatase Phosphodiest PF01663.22 CRK34970.1 - 4.5e-06 26.5 1.0 8e-06 25.7 1.0 1.5 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 CRK34970.1 - 5.7e-06 25.9 0.0 1e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.17 CRK34970.1 - 0.0022 16.7 0.8 0.0027 16.4 0.2 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF229) DUF1501 PF07394.12 CRK34970.1 - 0.047 12.8 0.2 0.071 12.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) DUF924 PF06041.11 CRK34975.1 - 2e-30 106.3 0.1 3.2e-30 105.6 0.1 1.3 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) Kelch_4 PF13418.6 CRK34975.1 - 1.6e-17 63.2 2.8 0.00022 21.2 0.0 5.2 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 CRK34975.1 - 2.2e-17 62.6 0.4 0.0021 18.0 0.0 5.4 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.6 CRK34975.1 - 1.5e-12 47.4 0.0 0.0012 19.1 0.0 5.8 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.6 CRK34975.1 - 1e-08 35.1 1.2 0.26 11.6 0.0 4.5 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 CRK34975.1 - 3.3e-06 26.6 3.5 0.018 14.6 0.0 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 CRK34975.1 - 0.068 13.2 6.9 1.1 9.4 0.0 4.4 5 0 0 5 5 5 0 Kelch motif Sugar_tr PF00083.24 CRK34976.1 - 1.8e-80 271.0 10.9 2.1e-80 270.8 10.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK34976.1 - 1.1e-22 80.5 23.6 1.3e-22 80.2 21.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CRK34976.1 - 2.4e-07 29.6 0.2 3.8e-07 28.9 0.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 CRK34976.1 - 2.8e-05 22.9 3.2 0.00089 17.9 0.0 2.6 2 0 0 2 2 2 2 MFS/sugar transport protein DUF3104 PF11302.8 CRK34976.1 - 0.019 14.7 0.2 0.053 13.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3104) OATP PF03137.20 CRK34976.1 - 0.031 12.6 4.0 0.038 12.3 0.8 2.7 3 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family TraU PF06834.11 CRK34976.1 - 0.035 13.4 0.0 0.056 12.7 0.0 1.2 1 0 0 1 1 1 0 TraU protein Fungal_trans_2 PF11951.8 CRK34985.1 - 1.9e-53 181.7 6.2 2.5e-53 181.3 6.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain AAA_lid_6 PF17866.1 CRK34985.1 - 0.047 13.9 0.1 0.12 12.6 0.1 1.6 1 0 0 1 1 1 0 AAA lid domain Metallophos PF00149.28 CRK34989.1 - 7.8e-09 36.3 0.1 1.1e-08 35.9 0.1 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase TMEM154 PF15102.6 CRK34990.1 - 0.003 17.5 1.7 0.0042 17.0 0.2 1.8 2 0 0 2 2 2 1 TMEM154 protein family SKG6 PF08693.10 CRK34990.1 - 0.0081 15.5 2.5 0.017 14.5 2.5 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain EphA2_TM PF14575.6 CRK34990.1 - 0.05 14.5 0.0 0.16 12.9 0.0 1.9 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain MFS_1 PF07690.16 CRK34992.1 - 1.4e-17 63.7 15.2 1.5e-15 57.0 12.1 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily Sm_multidrug_ex PF06695.11 CRK34992.1 - 0.069 13.8 1.7 3.7 8.2 0.1 3.2 2 1 1 3 3 3 0 Putative small multi-drug export protein RST PF12174.8 CRK34993.1 - 0.06 13.3 0.0 0.096 12.6 0.0 1.4 1 0 0 1 1 1 0 RCD1-SRO-TAF4 (RST) plant domain DNAPolymera_Pol PF11590.8 CRK34995.1 - 0.034 14.0 0.2 0.13 12.2 0.0 1.9 2 0 0 2 2 2 0 DNA polymerase catalytic subunit Pol PH_9 PF15410.6 CRK34999.1 - 0.1 13.0 0.0 0.1 13.0 0.0 1.1 1 0 0 1 1 1 0 Pleckstrin homology domain Glyco_hydro_88 PF07470.13 CRK35001.1 - 2.8e-90 302.9 4.8 3.1e-90 302.7 4.8 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_hydro_127 PF07944.12 CRK35001.1 - 0.04 12.4 0.4 0.055 11.9 0.4 1.1 1 0 0 1 1 1 0 Beta-L-arabinofuranosidase, GH127 Glyco_hydro_76 PF03663.14 CRK35001.1 - 0.5 9.8 8.5 0.1 12.1 0.4 3.0 2 1 2 4 4 4 0 Glycosyl hydrolase family 76 FAD-oxidase_C PF02913.19 CRK35003.1 - 5.5e-30 104.8 0.1 5.9e-30 104.7 0.1 1.0 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain CagY_M PF07337.11 CRK35003.1 - 0.14 11.8 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 DC-EC Repeat DUF3103 PF11301.8 CRK35006.1 - 0.18 10.6 0.0 0.24 10.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3103) Sec1 PF00995.23 CRK35008.1 - 6.2e-55 187.5 0.0 7.1e-55 187.3 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Abhydrolase_2 PF02230.16 CRK35010.1 - 3.5e-10 40.1 0.0 4.8e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase PH_10 PF15411.6 CRK35012.1 - 4.3e-24 85.1 0.4 4.5e-24 85.1 0.4 1.0 1 0 0 1 1 1 1 Pleckstrin homology domain SAP30_Sin3_bdg PF13867.6 CRK35014.1 - 5.7e-08 33.0 0.1 7.8e-08 32.5 0.1 1.2 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 SSF PF00474.17 CRK35016.1 - 2.9e-12 46.2 10.6 2.9e-12 46.2 10.6 1.6 2 0 0 2 2 2 1 Sodium:solute symporter family Bac_luciferase PF00296.20 CRK35017.1 - 5.2e-13 49.1 0.0 6.3e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Peptidase_S24 PF00717.23 CRK35018.1 - 5.5e-07 29.4 0.0 7.7e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like DUF1349 PF07081.11 CRK35020.1 - 1.3e-22 80.4 0.1 1.6e-22 80.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) TFIIB PF00382.19 CRK35021.1 - 2.7e-26 91.4 0.1 2.7e-18 65.8 0.0 2.6 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 CRK35021.1 - 3.5e-21 75.4 0.7 3.5e-21 75.4 0.7 3.1 4 0 0 4 4 4 1 Brf1-like TBP-binding domain Glyco_trans_1_2 PF13524.6 CRK35021.1 - 5.8 7.4 6.7 1.3 9.5 0.2 3.3 3 0 0 3 3 3 0 Glycosyl transferases group 1 RabGAP-TBC PF00566.18 CRK35022.1 - 3e-33 115.3 0.1 2.4e-17 63.3 0.0 3.2 2 1 0 2 2 2 2 Rab-GTPase-TBC domain Meiosis_expr PF15163.6 CRK35022.1 - 0.16 12.7 1.6 0.49 11.1 1.6 1.8 1 0 0 1 1 1 0 Meiosis-expressed Axin_b-cat_bind PF08833.10 CRK35023.1 - 7.6 6.7 7.7 1.5 9.0 3.8 1.8 1 1 1 2 2 2 0 Axin beta-catenin binding domain GRP PF07172.11 CRK35028.1 - 0.33 11.6 16.3 0.45 11.2 16.3 1.2 1 0 0 1 1 1 0 Glycine rich protein family Fungal_trans_2 PF11951.8 CRK35029.1 - 0.018 13.9 0.1 0.024 13.5 0.1 1.1 1 0 0 1 1 1 0 Fungal specific transcription factor domain peroxidase PF00141.23 CRK35031.1 - 1.1e-37 130.0 0.0 1.6e-37 129.4 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Adaptin_N PF01602.20 CRK35032.1 - 5e-27 94.7 0.0 5.4e-27 94.5 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.6 CRK35032.1 - 0.0088 16.4 0.1 0.013 15.9 0.1 1.2 1 0 0 1 1 1 1 HEAT repeats N_Asn_amidohyd PF14736.6 CRK35032.1 - 0.067 12.3 0.0 0.077 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein N-terminal asparagine amidohydrolase MBOAT PF03062.19 CRK35033.1 - 3.4e-19 69.4 5.2 3.5e-19 69.4 5.2 1.0 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 CRK35033.1 - 7.9e-05 22.8 2.7 0.00016 21.9 2.7 1.4 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family AtuA PF07287.11 CRK35036.1 - 2.6e-34 118.5 0.0 2.9e-34 118.4 0.0 1.0 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA MHC2-interact PF09307.10 CRK35046.1 - 0.38 10.8 1.9 0.57 10.2 1.9 1.3 1 0 0 1 1 1 0 CLIP, MHC2 interacting TPR_14 PF13428.6 CRK35048.1 - 7.6e-08 32.6 5.7 0.97 10.4 0.6 6.2 4 3 3 7 7 7 2 Tetratricopeptide repeat Suf PF05843.14 CRK35048.1 - 6.6e-07 29.6 2.0 0.018 15.1 0.2 3.7 1 1 2 3 3 3 2 Suppressor of forked protein (Suf) TPR_15 PF13429.6 CRK35048.1 - 7.9e-06 25.3 0.5 2.5e-05 23.6 0.3 1.9 2 1 0 2 2 2 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 CRK35048.1 - 0.00043 20.2 1.3 0.071 13.1 0.0 3.6 4 0 0 4 4 4 1 Mad3/BUB1 homology region 1 TPR_12 PF13424.6 CRK35048.1 - 0.00055 20.2 0.8 27 5.1 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 CRK35048.1 - 0.0074 16.4 2.5 18 5.9 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 CRK35048.1 - 0.11 12.3 9.1 17 5.5 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat MIT PF04212.18 CRK35048.1 - 0.37 10.9 2.3 0.62 10.2 0.2 2.6 3 1 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_2 PF07719.17 CRK35048.1 - 6.1 7.2 8.9 16 5.9 0.1 4.6 6 0 0 6 6 6 0 Tetratricopeptide repeat Milton PF12448.8 CRK35052.1 - 0.00029 21.0 0.8 0.00033 20.8 0.8 1.1 1 0 0 1 1 1 1 Kinesin associated protein Laminin_II PF06009.12 CRK35052.1 - 0.0023 18.0 0.8 0.0033 17.4 0.7 1.4 1 1 0 1 1 1 1 Laminin Domain II CHAD PF05235.14 CRK35052.1 - 0.02 14.9 2.6 0.022 14.8 2.6 1.0 1 0 0 1 1 1 0 CHAD domain Mtr2 PF10429.9 CRK35052.1 - 0.11 12.4 0.1 0.15 12.0 0.1 1.2 1 0 0 1 1 1 0 Nuclear pore RNA shuttling protein Mtr2 OmpH PF03938.14 CRK35052.1 - 0.42 10.9 6.5 0.59 10.5 6.5 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) FAA_hydrolase PF01557.18 CRK35055.1 - 8.2e-19 68.1 0.0 8.2e-19 68.1 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family MFS_1 PF07690.16 CRK35058.1 - 2.6e-49 168.0 22.3 2.6e-49 168.0 22.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK35058.1 - 1.3e-08 34.2 9.9 1.3e-08 34.2 9.9 2.6 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_3 PF05977.13 CRK35058.1 - 0.038 12.4 6.2 0.073 11.5 6.2 1.4 1 0 0 1 1 1 0 Transmembrane secretion effector OATP PF03137.20 CRK35058.1 - 0.24 9.7 4.6 0.09 11.1 1.5 1.7 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Syntaxin-18_N PF10496.9 CRK35059.1 - 9.9e-10 38.5 3.1 1.4e-09 38.1 0.8 2.5 2 1 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.19 CRK35059.1 - 0.031 14.3 0.0 0.1 12.6 0.0 1.9 1 0 0 1 1 1 0 SNARE domain XylR_N PF06505.11 CRK35059.1 - 0.33 10.7 2.1 0.49 10.2 0.4 2.0 1 1 1 2 2 2 0 Activator of aromatic catabolism BLOC1_2 PF10046.9 CRK35059.1 - 1.1 9.6 7.9 0.3 11.4 2.8 2.4 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Aminotran_1_2 PF00155.21 CRK35060.1 - 1.2e-85 287.9 0.0 1.4e-85 287.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II CoA_transf_3 PF02515.17 CRK35061.1 - 2.2e-44 152.1 0.6 1.2e-42 146.4 0.0 2.2 2 0 0 2 2 2 2 CoA-transferase family III Mito_carr PF00153.27 CRK35062.1 - 1.1e-19 70.1 0.2 1.9e-15 56.5 0.3 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein DUF4538 PF15061.6 CRK35063.1 - 0.0043 16.8 3.0 0.0067 16.1 3.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4538) Xpo1 PF08389.12 CRK35063.1 - 0.077 13.0 0.0 0.094 12.8 0.0 1.1 1 0 0 1 1 1 0 Exportin 1-like protein zf-PARP PF00645.18 CRK35064.1 - 4.5e-22 78.7 0.4 5.1e-22 78.5 0.4 1.0 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Mito_carr PF00153.27 CRK35065.1 - 1.1e-12 47.6 0.0 1.3e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial carrier protein Hexokinase_1 PF00349.21 CRK35066.1 - 2.6e-40 138.5 0.0 2.8e-40 138.3 0.0 1.0 1 0 0 1 1 1 1 Hexokinase ABC_membrane_2 PF06472.15 CRK35067.1 - 1.3e-12 47.7 0.0 1.6e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 DUF2373 PF10180.9 CRK35068.1 - 2e-24 85.2 0.3 2.6e-24 84.8 0.3 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Peptidase_M48 PF01435.18 CRK35069.1 - 3.8e-33 114.9 0.1 4.7e-33 114.6 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M48 SATase_N PF06426.14 CRK35069.1 - 0.06 13.7 0.0 13 6.2 0.0 2.2 2 0 0 2 2 2 0 Serine acetyltransferase, N-terminal Kinesin PF00225.23 CRK35070.1 - 3.4e-111 371.4 0.0 6e-111 370.6 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.8 CRK35070.1 - 9.9e-52 175.7 0.1 3.6e-51 173.9 0.0 2.1 2 0 0 2 2 2 1 Kinesin protein Microtub_bd PF16796.5 CRK35070.1 - 4e-25 88.5 0.0 1e-24 87.2 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding Kinesin_assoc PF16183.5 CRK35070.1 - 4.7e-23 82.3 11.5 8.6e-19 68.4 0.9 2.9 2 1 1 3 3 3 2 Kinesin-associated KIF1B PF12423.8 CRK35070.1 - 3.7e-07 30.5 0.4 1.1e-06 29.0 0.4 1.8 1 0 0 1 1 1 1 Kinesin protein 1B Peptidase_M1 PF01433.20 CRK35071.1 - 1.4e-42 145.8 0.4 1.9e-42 145.3 0.4 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 CRK35071.1 - 2.7e-39 133.8 0.0 4.8e-39 132.9 0.0 1.4 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 CRK35071.1 - 2.1e-31 109.6 0.2 4.1e-31 108.6 0.2 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain KdgM PF06178.13 CRK35074.1 - 0.14 11.7 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Oligogalacturonate-specific porin protein (KdgM) Ezh2_MCSS PF18600.1 CRK35077.1 - 2.6e-24 84.6 1.3 5.2e-24 83.6 1.3 1.6 1 0 0 1 1 1 1 MCSS domain SET PF00856.28 CRK35077.1 - 5.9e-10 39.8 1.9 1.1e-09 38.9 0.5 2.2 2 1 0 2 2 2 1 SET domain EZH2_N PF18601.1 CRK35077.1 - 5.3e-09 36.3 0.1 1.1e-08 35.2 0.1 1.6 1 0 0 1 1 1 1 EZH2 N-terminal domain ECSCR PF15820.5 CRK35077.1 - 0.074 12.9 0.1 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Insulin_TMD PF17870.1 CRK35077.1 - 0.14 12.2 0.2 0.25 11.4 0.2 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Pil1 PF13805.6 CRK35078.1 - 1e-124 415.3 0.2 1.3e-124 414.9 0.2 1.2 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.11 CRK35078.1 - 0.064 12.7 2.1 0.2 11.1 2.1 1.9 1 1 0 1 1 1 0 FAM92 protein LSM PF01423.22 CRK35079.1 - 1.3e-10 40.8 0.0 1.8e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 LSM domain G-alpha PF00503.20 CRK35080.1 - 2.3e-32 112.5 0.5 2.5e-32 112.4 0.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit zf-CHC2 PF01807.20 CRK35080.1 - 2.5e-05 24.0 0.1 3e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 CHC2 zinc finger HET PF06985.11 CRK35085.1 - 6.2e-11 42.8 8.4 2.5e-09 37.6 0.8 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Kelch_5 PF13854.6 CRK35086.1 - 1.5e-15 56.8 8.0 1.2e-07 31.5 0.0 4.8 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 CRK35086.1 - 3.4e-11 43.0 11.2 0.18 11.9 0.0 6.2 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.6 CRK35086.1 - 1.4e-06 28.4 3.6 0.52 10.7 0.1 5.6 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.6 CRK35086.1 - 4.1e-06 26.9 17.5 0.0068 16.7 0.1 6.4 6 1 0 6 6 6 2 Galactose oxidase, central domain Kelch_1 PF01344.25 CRK35086.1 - 2.3e-05 23.9 11.1 0.31 10.7 0.1 5.8 6 0 0 6 6 6 2 Kelch motif Kelch_2 PF07646.15 CRK35086.1 - 0.064 13.3 0.1 0.064 13.3 0.1 4.5 6 1 0 6 6 6 0 Kelch motif PBP1_TM PF14812.6 CRK35086.1 - 3 8.3 7.2 8.4 6.8 7.2 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC45 PF02724.14 CRK35086.1 - 8.3 4.6 6.7 11 4.1 6.7 1.1 1 0 0 1 1 1 0 CDC45-like protein TusA PF01206.17 CRK35087.1 - 0.094 12.6 0.0 0.19 11.5 0.0 1.6 1 1 1 2 2 2 0 Sulfurtransferase TusA Arf PF00025.21 CRK35090.1 - 6e-37 126.8 0.0 6.5e-37 126.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 CRK35090.1 - 3.8e-07 29.6 0.0 8.3e-07 28.5 0.0 1.4 1 1 0 1 1 1 1 G-protein alpha subunit Ras PF00071.22 CRK35090.1 - 4.6e-05 23.1 0.0 5.2e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CRK35090.1 - 0.00029 21.0 0.0 0.00037 20.7 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 CRK35090.1 - 0.036 13.4 0.0 0.045 13.1 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CRK35090.1 - 0.042 13.4 0.0 0.048 13.2 0.0 1.1 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain SRPRB PF09439.10 CRK35090.1 - 0.068 12.6 0.0 0.079 12.4 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit USP7_C2 PF14533.6 CRK35090.1 - 0.11 12.2 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin-specific protease C-terminal Ribosomal_L22 PF00237.19 CRK35092.1 - 6.1e-10 39.3 0.4 1.1e-09 38.4 0.4 1.5 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e EcsC PF12787.7 CRK35092.1 - 0.017 14.8 1.4 0.022 14.4 1.4 1.2 1 0 0 1 1 1 0 EcsC protein family DUF4986 PF16375.5 CRK35092.1 - 0.059 14.0 0.3 0.088 13.5 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function RRF_GI PF12614.8 CRK35092.1 - 0.059 13.5 1.8 0.073 13.2 1.8 1.1 1 0 0 1 1 1 0 Ribosome recycling factor Fungal_trans_2 PF11951.8 CRK35094.1 - 1.3e-71 241.5 0.0 1.6e-71 241.2 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK35094.1 - 1.2e-08 34.9 6.9 2e-08 34.2 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 CRK35095.1 - 1.4e-65 221.6 0.0 1.9e-65 221.2 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain FerI PF08151.12 CRK35095.1 - 0.11 12.7 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 FerI (NUC094) domain Podoplanin PF05808.11 CRK35097.1 - 0.0035 17.5 0.0 0.01 16.0 0.0 1.8 1 0 0 1 1 1 1 Podoplanin TMEM51 PF15345.6 CRK35097.1 - 0.0038 17.1 0.2 0.0069 16.3 0.1 1.5 1 1 0 1 1 1 1 Transmembrane protein 51 Trp_oprn_chp PF09534.10 CRK35097.1 - 0.0093 15.8 1.6 0.06 13.1 0.1 2.2 2 0 0 2 2 2 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) EphA2_TM PF14575.6 CRK35097.1 - 0.017 16.0 0.0 0.036 14.9 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 CRK35097.1 - 0.032 14.1 0.0 0.072 13.0 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family Mid2 PF04478.12 CRK35097.1 - 0.056 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor BAG6 PF12057.8 CRK35097.1 - 0.063 13.0 1.5 0.33 10.7 0.1 2.7 3 0 0 3 3 3 0 BCL2-associated athanogene 6 SKG6 PF08693.10 CRK35097.1 - 0.2 11.1 2.2 0.48 9.9 2.2 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain SPX PF03105.19 CRK35097.1 - 0.85 9.5 7.6 1.2 9.0 7.6 1.2 1 0 0 1 1 1 0 SPX domain DUF4187 PF13821.6 CRK35098.1 - 1.3e-21 76.1 0.7 3.1e-21 74.9 0.7 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 CRK35098.1 - 1.7e-13 50.2 11.7 2.2e-06 27.5 2.2 2.6 2 0 0 2 2 2 2 G-patch domain G-patch_2 PF12656.7 CRK35098.1 - 0.085 13.0 12.2 2 8.6 2.4 2.9 2 0 0 2 2 2 0 G-patch domain DUF3106 PF11304.8 CRK35099.1 - 0.026 15.0 0.4 0.033 14.7 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3106) BAG6 PF12057.8 CRK35100.1 - 0.019 14.6 0.1 0.029 14.1 0.1 1.2 1 0 0 1 1 1 0 BCL2-associated athanogene 6 DUF4187 PF13821.6 CRK35101.1 - 1.3e-21 76.1 1.0 3.4e-21 74.8 1.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) PPR_2 PF13041.6 CRK35102.1 - 5.4e-05 23.3 0.1 0.00026 21.1 0.0 2.3 3 0 0 3 3 3 1 PPR repeat family PPR_1 PF12854.7 CRK35102.1 - 0.057 13.1 0.0 1.1 9.1 0.0 2.6 2 0 0 2 2 2 0 PPR repeat PPR PF01535.20 CRK35102.1 - 0.1 12.9 0.0 0.45 10.9 0.0 2.2 1 0 0 1 1 1 0 PPR repeat DUF1746 PF08508.10 CRK35104.1 - 2.1e-40 137.6 0.1 3e-40 137.1 0.1 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) tRNA-synt_2d PF01409.20 CRK35105.1 - 4.6e-86 288.3 0.0 6.2e-86 287.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 CRK35105.1 - 1.9e-15 56.8 0.9 4.1e-15 55.8 0.9 1.6 1 0 0 1 1 1 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 CRK35105.1 - 1.4e-05 24.7 0.0 0.0072 15.8 0.0 2.9 3 0 0 3 3 3 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 CRK35105.1 - 3.5e-05 23.0 0.2 0.0016 17.6 0.0 3.0 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) PheRS_DBD2 PF18554.1 CRK35105.1 - 5.1e-05 23.2 4.1 0.00017 21.5 4.1 2.0 1 0 0 1 1 1 1 PheRS DNA binding domain 2 tRNA-synt_2b PF00587.25 CRK35105.1 - 0.059 13.3 0.0 0.23 11.4 0.0 2.0 1 1 1 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) CPSase_L_D2 PF02786.17 CRK35106.1 - 2.6e-109 363.6 0.1 2.4e-84 282.0 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.22 CRK35106.1 - 6.3e-22 78.0 0.1 5.8e-11 42.3 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 CRK35106.1 - 1.3e-19 70.5 0.7 6.8e-09 35.6 0.1 2.3 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 CRK35106.1 - 4.6e-12 45.8 0.0 3.9e-05 23.4 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon GARS_A PF01071.19 CRK35106.1 - 1.9e-05 24.5 1.0 0.064 13.0 0.1 2.9 3 0 0 3 3 3 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_3 PF02655.14 CRK35106.1 - 2.3e-05 24.5 0.4 0.34 10.9 0.0 2.8 3 0 0 3 3 3 2 ATP-grasp domain ATP-grasp_5 PF13549.6 CRK35106.1 - 4.2e-05 23.1 0.1 0.18 11.2 0.0 2.8 2 0 0 2 2 2 2 ATP-grasp domain RimK PF08443.11 CRK35106.1 - 0.0002 21.0 0.0 0.23 11.0 0.0 2.6 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_4 PF13535.6 CRK35106.1 - 0.0044 16.6 0.0 0.066 12.8 0.0 2.5 2 0 0 2 2 2 1 ATP-grasp domain GSH-S_ATP PF02955.16 CRK35106.1 - 0.12 11.8 0.0 0.28 10.5 0.0 1.6 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain NPL4 PF05021.15 CRK35107.1 - 4.9e-22 78.7 0.0 6.3e-22 78.3 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 CRK35108.1 - 3.3e-67 225.1 0.1 4.7e-67 224.6 0.1 1.2 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region NPL4 PF05021.15 CRK35108.1 - 8e-42 143.7 0.0 1.2e-41 143.1 0.0 1.2 1 0 0 1 1 1 1 NPL4 family UN_NPL4 PF11543.8 CRK35108.1 - 2.8e-05 24.5 0.0 5.3e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 Sec66 PF09802.9 CRK35109.1 - 4.9e-80 267.4 0.1 5.6e-80 267.2 0.1 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 DUF3848 PF12959.7 CRK35109.1 - 0.035 14.2 0.0 0.081 13.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3848) PaREP1 PF05942.11 CRK35109.1 - 0.21 11.5 1.3 0.74 9.8 0.2 2.0 1 1 1 2 2 2 0 Archaeal PaREP1/PaREP8 family ORC3_N PF07034.11 CRK35111.1 - 5.3e-38 130.9 0.2 1.8e-35 122.6 0.2 2.5 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 CRK35111.1 - 8.3e-25 87.5 0.0 8.3e-25 87.5 0.0 5.9 5 2 0 5 5 5 1 Origin recognition complex winged helix C-terminal PWWP PF00855.17 CRK35111.1 - 3.2e-12 46.7 0.0 1.4e-11 44.6 0.0 2.2 1 0 0 1 1 1 1 PWWP domain Secretin_N PF03958.17 CRK35111.1 - 4 7.9 6.1 14 6.1 0.0 3.7 3 0 0 3 3 3 0 Bacterial type II/III secretion system short domain Sec63 PF02889.16 CRK35112.1 - 5.2e-132 438.7 0.0 7.5e-94 313.7 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 CRK35112.1 - 1.9e-38 132.0 0.0 1.1e-18 67.6 0.0 3.1 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 CRK35112.1 - 8.1e-34 116.1 1.2 2.4e-33 114.6 1.2 1.9 1 0 0 1 1 1 1 N-terminal helicase PWI domain ResIII PF04851.15 CRK35112.1 - 4.3e-16 59.4 0.0 7.7e-07 29.3 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CRK35112.1 - 1.9e-09 37.9 0.0 3.5e-07 30.6 0.0 3.6 2 2 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 CRK35112.1 - 0.00025 21.3 0.0 0.4 10.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain HTH_31 PF13560.6 CRK35112.1 - 0.12 12.7 0.0 0.45 10.9 0.0 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain TFIIE_alpha PF02002.17 CRK35112.1 - 0.13 12.2 0.8 0.57 10.1 0.1 2.4 2 0 0 2 2 2 0 TFIIE alpha subunit DUF3140 PF11338.8 CRK35113.1 - 0.011 16.2 3.4 0.28 11.6 0.1 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3140) Rep_fac_C PF08542.11 CRK35114.1 - 1.2e-19 70.5 0.0 2.2e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 CRK35114.1 - 3.5e-17 63.1 0.1 2e-16 60.6 0.0 2.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 CRK35114.1 - 4.5e-13 49.3 0.0 2.9e-12 46.7 0.0 2.1 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 CRK35114.1 - 3.8e-09 36.7 0.0 9.2e-09 35.5 0.0 1.7 1 1 0 1 1 1 1 Rad17 P-loop domain RuvB_N PF05496.12 CRK35114.1 - 9.2e-06 25.5 0.0 3.2e-05 23.7 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CRK35114.1 - 1.2e-05 25.7 0.0 0.00078 19.9 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_assoc_2 PF16193.5 CRK35114.1 - 1.3e-05 25.4 0.0 3.7e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 AAA C-terminal domain AAA_22 PF13401.6 CRK35114.1 - 5.1e-05 23.6 0.1 0.00066 20.0 0.0 2.6 2 1 0 2 2 1 1 AAA domain DNA_pol3_delta PF06144.13 CRK35114.1 - 5.1e-05 23.1 0.0 9.6e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_11 PF13086.6 CRK35114.1 - 6.6e-05 22.8 0.1 0.00016 21.5 0.1 1.7 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 CRK35114.1 - 0.00044 19.7 0.0 0.018 14.5 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 CRK35114.1 - 0.001 19.1 0.0 0.0023 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CRK35114.1 - 0.0016 18.5 0.1 0.012 15.6 0.1 2.5 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 CRK35114.1 - 0.0024 17.1 0.0 0.0038 16.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_30 PF13604.6 CRK35114.1 - 0.0029 17.3 0.0 0.014 15.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 CRK35114.1 - 0.0038 17.0 0.0 0.011 15.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CRK35114.1 - 0.004 17.5 0.0 0.026 14.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 CRK35114.1 - 0.0047 16.2 0.0 0.012 14.9 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 CRK35114.1 - 0.009 15.5 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_28 PF13521.6 CRK35114.1 - 0.0092 16.2 0.0 0.017 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 CRK35114.1 - 0.026 14.5 0.0 0.29 11.1 0.0 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_18 PF13238.6 CRK35114.1 - 0.036 14.6 0.0 0.11 13.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CRK35114.1 - 0.044 14.2 0.0 0.1 13.0 0.0 1.7 1 1 0 1 1 1 0 RNA helicase AAA_3 PF07726.11 CRK35114.1 - 0.054 13.4 0.0 0.33 10.8 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 CRK35114.1 - 0.074 13.2 0.0 0.18 12.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain DEAD PF00270.29 CRK35114.1 - 0.092 12.5 0.1 0.91 9.3 0.0 2.3 1 1 1 2 2 2 0 DEAD/DEAH box helicase UQ_con PF00179.26 CRK35115.1 - 2.4e-40 137.4 0.0 8.6e-27 93.5 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CRK35115.1 - 0.0011 18.7 0.0 0.081 12.6 0.0 2.3 2 0 0 2 2 2 2 Prokaryotic E2 family B RWD PF05773.22 CRK35115.1 - 0.011 16.1 0.0 5.6 7.3 0.0 2.5 2 1 0 2 2 2 0 RWD domain PGA2 PF07543.12 CRK35118.1 - 0.093 12.7 0.4 0.18 11.7 0.4 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 DUF2417 PF10329.9 CRK35120.1 - 4.1e-83 278.4 3.9 6e-83 277.9 3.9 1.3 1 0 0 1 1 1 1 Region of unknown function (DUF2417) DUF2070 PF09843.9 CRK35120.1 - 0.41 8.9 14.8 0.65 8.2 14.8 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Oxysterol_BP PF01237.18 CRK35122.1 - 5.7e-89 298.6 0.0 1.7e-86 290.4 0.0 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein DUF4195 PF13836.6 CRK35123.1 - 0.065 13.3 1.6 0.084 13.0 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4195) Hamartin PF04388.12 CRK35123.1 - 4.3 5.9 5.2 4.3 5.9 5.2 1.0 1 0 0 1 1 1 0 Hamartin protein Totivirus_coat PF05518.11 CRK35123.1 - 4.8 5.1 14.5 5.7 4.9 14.5 1.0 1 0 0 1 1 1 0 Totivirus coat protein DUF1631 PF07793.11 CRK35123.1 - 6.2 5.1 10.7 6.6 5.0 10.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) zf-CCCH PF00642.24 CRK35125.1 - 1.3e-08 34.5 18.0 5.4e-07 29.4 2.6 3.0 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 CRK35125.1 - 0.0045 17.7 2.2 0.41 11.4 0.2 2.4 2 0 0 2 2 2 2 Torus domain RRM_1 PF00076.22 CRK35125.1 - 0.0073 16.1 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 CRK35125.1 - 0.012 15.6 2.9 0.012 15.6 2.9 3.0 3 0 0 3 3 3 0 Zinc finger domain zf-CCCH_3 PF15663.5 CRK35125.1 - 0.058 13.6 2.3 0.38 11.0 0.1 2.4 2 1 0 2 2 2 0 Zinc-finger containing family SCRG1 PF15224.6 CRK35125.1 - 0.12 12.5 1.7 0.58 10.3 0.1 2.3 2 0 0 2 2 2 0 Scrapie-responsive protein 1 Aldo_ket_red PF00248.21 CRK35127.1 - 2.7e-68 230.3 0.0 3.2e-68 230.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3425 PF11905.8 CRK35129.1 - 1.1e-19 70.6 0.0 2e-19 69.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) WSN PF02206.18 CRK35129.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function bZIP_1 PF00170.21 CRK35129.1 - 0.26 11.4 5.9 0.48 10.5 5.9 1.3 1 0 0 1 1 1 0 bZIP transcription factor Sugar_tr PF00083.24 CRK35131.1 - 4.6e-78 263.1 19.6 5.5e-78 262.8 19.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK35131.1 - 7.1e-16 58.1 20.2 7.1e-16 58.1 20.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3169 PF11368.8 CRK35131.1 - 4.9 6.6 9.4 2.8 7.4 0.0 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF3169) DUF443 PF04276.12 CRK35131.1 - 7.3 6.3 8.4 0.67 9.7 0.4 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF443) ELMO_CED12 PF04727.13 CRK35133.1 - 3.2e-49 167.5 0.0 4.6e-49 166.9 0.0 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family PH_12 PF16457.5 CRK35133.1 - 1.7e-34 119.2 0.0 4.7e-34 117.8 0.0 1.7 1 1 0 1 1 1 1 Pleckstrin homology domain DUF3361 PF11841.8 CRK35133.1 - 1.9e-13 50.6 0.0 3.8e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) Fungal_trans PF04082.18 CRK35136.1 - 2.2e-15 56.4 2.0 7.6e-15 54.7 1.1 1.9 1 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK35136.1 - 4.4e-08 33.1 12.3 9.3e-08 32.1 12.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MGC-24 PF05283.11 CRK35136.1 - 0.59 10.6 14.0 0.2 12.1 10.5 2.0 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF3439 PF11921.8 CRK35136.1 - 1 9.3 7.1 2.2 8.3 7.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.12 CRK35136.1 - 1.2 7.0 2.4 1.6 6.6 2.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein FAD_binding_2 PF00890.24 CRK35138.1 - 7.2e-122 407.5 4.7 1.2e-121 406.8 4.7 1.4 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 CRK35138.1 - 1e-42 145.1 0.2 2.1e-42 144.1 0.2 1.6 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term zf-GRF PF06839.12 CRK35138.1 - 3.7e-05 23.7 6.5 3.7e-05 23.7 6.5 2.7 2 0 0 2 2 2 1 GRF zinc finger Thi4 PF01946.17 CRK35138.1 - 0.00012 21.5 0.2 0.028 13.7 0.1 2.4 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.22 CRK35138.1 - 0.00035 19.8 0.4 0.089 11.9 1.2 2.4 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 CRK35138.1 - 0.0006 19.1 0.6 0.058 12.6 0.2 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CRK35138.1 - 0.013 14.7 0.6 0.03 13.6 0.1 1.8 2 0 0 2 2 2 0 FAD binding domain bZIP_1 PF00170.21 CRK35138.1 - 0.015 15.3 0.5 0.042 14.0 0.5 1.6 1 0 0 1 1 1 0 bZIP transcription factor TMF_DNA_bd PF12329.8 CRK35138.1 - 7.2 6.7 7.5 0.3 11.1 0.3 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF3818 PF12825.7 CRK35141.1 - 5.1e-129 430.1 4.2 9e-129 429.3 4.2 1.4 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) Fungal_trans PF04082.18 CRK35141.1 - 8.4e-15 54.5 1.6 2.5e-14 53.0 0.8 1.8 1 1 0 2 2 2 1 Fungal specific transcription factor domain PX PF00787.24 CRK35141.1 - 2e-12 47.1 0.0 1.2e-11 44.6 0.0 2.4 1 1 0 1 1 1 1 PX domain Zn_clus PF00172.18 CRK35141.1 - 1.2e-07 31.7 12.3 2.4e-07 30.7 12.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3802 PF12290.8 CRK35141.1 - 0.0061 17.1 0.4 0.019 15.4 0.4 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3802) MGC-24 PF05283.11 CRK35141.1 - 5.8 7.4 16.1 0.29 11.6 9.7 2.1 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin PH_12 PF16457.5 CRK35142.1 - 0.00086 19.9 0.1 0.0012 19.4 0.1 1.2 1 0 0 1 1 1 1 Pleckstrin homology domain FAD_binding_2 PF00890.24 CRK35143.1 - 2.4e-122 409.0 4.7 3.1e-122 408.7 4.7 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 CRK35143.1 - 6.1e-43 145.9 0.2 9.3e-43 145.3 0.2 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Thi4 PF01946.17 CRK35143.1 - 3.7e-05 23.1 0.3 0.015 14.6 0.1 2.3 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.22 CRK35143.1 - 0.00011 21.4 1.1 0.047 12.8 1.2 2.5 3 0 0 3 3 3 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 CRK35143.1 - 0.00012 21.4 0.7 0.024 13.9 0.2 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CRK35143.1 - 0.0049 16.2 0.6 0.016 14.5 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 CRK35143.1 - 0.091 12.3 1.3 0.22 11.1 1.3 1.8 1 1 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 CRK35143.1 - 0.24 10.0 0.7 0.71 8.5 0.2 2.0 2 0 0 2 2 2 0 HI0933-like protein SelP_N PF04592.14 CRK35144.1 - 0.55 9.6 7.8 1 8.7 7.8 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Herpes_LMP1 PF05297.11 CRK35144.1 - 9.3 5.3 6.1 9 5.4 5.1 1.4 1 1 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Cgr1 PF03879.14 CRK35145.1 - 3.1e-33 114.4 27.2 3.6e-33 114.2 27.2 1.0 1 0 0 1 1 1 1 Cgr1 family REC1 PF18501.1 CRK35145.1 - 0.64 9.9 13.4 0.76 9.6 13.4 1.1 1 0 0 1 1 1 0 Alpha helical recognition lobe domain RNA_polI_A34 PF08208.11 CRK35145.1 - 1.1 9.4 17.9 1.3 9.1 17.9 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 RR_TM4-6 PF06459.12 CRK35145.1 - 2 8.2 13.7 2 8.2 13.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AAA_11 PF13086.6 CRK35145.1 - 3.2 7.5 10.9 3.3 7.4 10.9 1.1 1 0 0 1 1 1 0 AAA domain COX16 PF14138.6 CRK35145.1 - 5 7.7 12.0 9.2 6.9 12.0 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 Presenilin PF01080.17 CRK35145.1 - 7.9 5.1 7.4 8.8 5.0 7.4 1.0 1 0 0 1 1 1 0 Presenilin DUF3818 PF12825.7 CRK35146.1 - 1e-129 432.4 3.9 1.6e-129 431.8 3.9 1.3 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 CRK35146.1 - 1.3e-64 216.0 3.9 2.9e-38 130.8 1.4 2.5 2 0 0 2 2 2 2 PX-associated PX PF00787.24 CRK35146.1 - 1.4e-12 47.6 2.0 2e-12 47.1 0.0 2.4 3 0 0 3 3 3 1 PX domain DUF3802 PF12290.8 CRK35146.1 - 0.0035 17.8 0.4 0.014 15.9 0.4 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3802) Cgr1 PF03879.14 CRK35147.1 - 5.8e-25 87.8 21.2 5.8e-25 87.8 21.2 3.1 3 1 1 4 4 4 1 Cgr1 family DUF1514 PF07438.11 CRK35147.1 - 0.049 13.5 2.3 0.11 12.4 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1514) DUF4140 PF13600.6 CRK35147.1 - 0.73 10.3 9.9 5.7 7.5 0.2 3.5 3 1 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) REC1 PF18501.1 CRK35147.1 - 4.7 7.0 13.5 0.26 11.2 7.3 1.9 2 1 1 3 3 3 0 Alpha helical recognition lobe domain UQ_con PF00179.26 CRK35148.1 - 6.3e-27 93.9 0.0 1.3e-26 92.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Spt5_N PF11942.8 CRK35148.1 - 1.3 10.1 8.3 3.8 8.6 8.3 1.7 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Anp1 PF03452.14 CRK35149.1 - 5.7e-67 225.9 0.0 6.5e-67 225.7 0.0 1.0 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 CRK35149.1 - 0.086 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 2 RRM_1 PF00076.22 CRK35150.1 - 2.4e-16 59.3 0.0 3.8e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 CRK35150.1 - 2e-05 25.0 9.7 2e-05 25.0 9.7 3.6 3 1 0 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 SHR3_chaperone PF08229.11 CRK35153.1 - 1.1e-25 89.8 0.0 1.4e-25 89.4 0.0 1.1 1 0 0 1 1 1 1 ER membrane protein SH3 SlyX PF04102.12 CRK35154.1 - 0.0031 18.1 1.0 1.1 9.9 0.3 2.6 2 0 0 2 2 2 2 SlyX DUF202 PF02656.15 CRK35155.1 - 2.4e-22 79.1 1.4 2.4e-22 79.1 1.4 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Aldo_ket_red PF00248.21 CRK35156.1 - 1.4e-57 195.1 0.0 1.6e-57 195.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Diphthami_syn_2 PF01902.17 CRK35157.1 - 1.5e-23 83.4 0.0 1.8e-18 66.9 0.0 3.3 2 1 0 2 2 2 2 Diphthamide synthase Ribonuc_L-PSP PF01042.21 CRK35157.1 - 4.9e-11 42.7 0.0 2e-06 27.8 0.0 3.3 3 1 0 3 3 3 2 Endoribonuclease L-PSP WD40 PF00400.32 CRK35158.1 - 1.5e-08 35.2 5.5 0.00045 21.0 0.0 6.8 7 0 0 7 7 7 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK35158.1 - 2.6e-06 27.6 0.0 0.52 10.6 0.0 4.9 5 0 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 CRK35158.1 - 9.6e-05 22.4 0.0 0.00025 21.0 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 CRK35158.1 - 0.0001 22.6 0.0 0.026 14.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain PD40 PF07676.12 CRK35158.1 - 0.00012 21.9 0.8 2.8 8.0 0.0 4.0 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat AAA_16 PF13191.6 CRK35158.1 - 0.0072 16.7 0.0 0.026 14.9 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain KAP_NTPase PF07693.14 CRK35158.1 - 0.053 12.8 0.1 0.42 9.8 0.1 2.1 1 1 0 1 1 1 0 KAP family P-loop domain NB-ARC PF00931.22 CRK35158.1 - 0.081 12.1 0.0 0.29 10.3 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain Fructosamin_kin PF03881.14 CRK35159.1 - 2.5e-35 122.1 0.0 3.4e-35 121.7 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 CRK35159.1 - 0.00061 19.8 0.1 0.001 19.1 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family zf-C2H2 PF00096.26 CRK35160.1 - 2.3e-14 52.9 11.0 2.3e-07 30.9 0.5 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CRK35160.1 - 5.6e-10 39.2 10.5 2.7e-08 33.9 3.0 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CRK35160.1 - 2e-09 37.5 9.2 0.00047 20.8 0.2 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 CRK35160.1 - 2.3e-08 34.2 3.9 2.1e-05 24.7 0.3 2.4 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CRK35160.1 - 8.1e-08 32.4 3.6 0.00028 21.1 0.7 2.3 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf_C2H2_ZHX PF18387.1 CRK35160.1 - 0.00017 21.1 2.2 0.084 12.5 0.2 2.3 1 1 1 2 2 2 2 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_6 PF13912.6 CRK35160.1 - 0.0017 18.3 11.2 0.023 14.7 0.7 2.9 2 1 0 2 2 2 2 C2H2-type zinc finger zf-LYAR PF08790.11 CRK35160.1 - 0.0061 16.4 2.1 0.15 12.0 0.2 2.4 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger Zn-ribbon_8 PF09723.10 CRK35160.1 - 0.0065 16.6 1.6 0.75 10.0 0.2 2.3 2 0 0 2 2 2 1 Zinc ribbon domain zf-trcl PF13451.6 CRK35160.1 - 0.018 14.9 2.9 0.29 11.0 0.4 2.4 2 0 0 2 2 2 0 Probable zinc-ribbon domain zf-C2H2_11 PF16622.5 CRK35160.1 - 0.018 14.8 6.1 1.3 8.8 0.1 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-AN1 PF01428.16 CRK35160.1 - 0.039 14.1 1.9 1.9 8.8 0.2 2.3 2 0 0 2 2 2 0 AN1-like Zinc finger zf-C2H2_2 PF12756.7 CRK35160.1 - 0.047 14.0 3.3 2.4 8.5 0.4 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf_UBZ PF18439.1 CRK35160.1 - 0.052 13.1 7.6 0.22 11.1 0.1 2.8 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-UBR PF02207.20 CRK35160.1 - 0.08 13.1 1.2 0.13 12.4 1.2 1.3 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) zf-BED PF02892.15 CRK35160.1 - 0.089 12.8 6.0 0.23 11.5 1.8 2.3 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_3rep PF18868.1 CRK35160.1 - 0.091 13.4 3.0 4.1 8.1 0.5 2.3 1 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats LIM PF00412.22 CRK35160.1 - 0.2 11.9 4.1 0.93 9.8 4.1 2.0 1 1 0 1 1 1 0 LIM domain zf-C2HC_2 PF13913.6 CRK35160.1 - 0.21 11.6 7.2 1.3 9.0 2.6 2.2 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Elf1 PF05129.13 CRK35160.1 - 0.29 11.2 5.0 3.8 7.6 0.7 2.3 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like HNH PF01844.23 CRK35160.1 - 0.29 11.3 3.1 6 7.1 0.1 2.9 2 1 0 2 2 2 0 HNH endonuclease Actin_micro PF17003.5 CRK35160.1 - 0.34 10.0 2.5 1.8 7.6 2.5 1.9 1 1 0 1 1 1 0 Putative actin-like family DUF629 PF04780.12 CRK35160.1 - 0.62 8.5 4.5 2.7 6.4 0.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf-C2HE PF16278.5 CRK35160.1 - 5.5 7.5 7.0 9.9 6.7 0.5 2.4 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2 PF00096.26 CRK35161.1 - 1.1e-12 47.7 11.0 2.3e-06 27.8 0.5 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CRK35161.1 - 1.3e-07 31.7 10.6 2.7e-07 30.7 3.0 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.7 CRK35161.1 - 1.6e-06 28.3 3.9 0.0002 21.6 0.3 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CRK35161.1 - 6.1e-06 26.4 3.6 0.0026 18.0 0.7 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 CRK35161.1 - 0.0002 21.9 9.2 0.0047 17.7 0.2 3.3 4 0 0 4 4 2 2 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 CRK35161.1 - 0.014 15.0 2.2 0.93 9.2 0.2 2.4 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_6 PF13912.6 CRK35161.1 - 0.031 14.3 8.4 0.22 11.6 0.7 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-LYAR PF08790.11 CRK35161.1 - 0.29 11.1 2.1 1.3 9.0 0.2 2.5 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2H2_11 PF16622.5 CRK35161.1 - 1.2 8.9 6.1 12 5.8 0.1 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type zf_UBZ PF18439.1 CRK35161.1 - 2 8.0 7.3 2 8.1 0.1 3.0 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 CRK35161.1 - 2.8 8.1 4.9 9.5 6.4 0.6 2.5 1 1 1 2 2 2 0 Zinc ribbon domain zf-BED PF02892.15 CRK35161.1 - 3.2 7.8 5.2 2 8.5 1.4 2.2 1 1 1 2 2 2 0 BED zinc finger S4_2 PF13275.6 CRK35162.1 - 0.083 12.7 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 S4 domain MutS_V PF00488.21 CRK35163.1 - 3e-65 219.8 0.0 1e-64 218.1 0.0 2.0 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.18 CRK35163.1 - 2.7e-32 112.5 0.9 5.3e-32 111.6 0.9 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 CRK35163.1 - 1.4e-29 102.6 0.0 3.3e-29 101.4 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 CRK35163.1 - 2.6e-10 40.7 0.0 1.1e-09 38.7 0.0 2.1 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 CRK35163.1 - 0.00033 21.0 0.0 0.00092 19.5 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV DUF4911 PF16256.5 CRK35163.1 - 0.05 13.6 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4911) Prenyltrans PF00432.21 CRK35165.1 - 1.5e-51 171.8 7.8 1.5e-12 47.0 0.1 6.1 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 CRK35165.1 - 0.0081 15.3 0.0 1 8.4 0.0 2.9 2 1 1 3 3 3 2 Squalene-hopene cyclase N-terminal domain Peptidase_M28 PF04389.17 CRK35166.1 - 6.4e-38 130.4 0.1 8.6e-38 130.0 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 CRK35166.1 - 1.2e-13 50.9 0.0 2.5e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 CRK35166.1 - 0.0001 22.1 0.1 0.00019 21.2 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 RhoGAP PF00620.27 CRK35168.1 - 1.5e-28 99.6 0.0 2.7e-28 98.7 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain SCIMP PF15050.6 CRK35168.1 - 0.33 11.4 1.1 1.9 9.0 1.1 2.3 1 0 0 1 1 1 0 SCIMP protein RRS1 PF04939.12 CRK35169.1 - 2.3e-57 193.4 1.2 2.6e-57 193.2 1.2 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) DAP3 PF10236.9 CRK35170.1 - 2.6e-90 302.8 0.0 3.6e-69 233.3 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 CRK35170.1 - 0.0014 19.0 0.0 0.0064 16.9 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain MCM PF00493.23 CRK35171.1 - 6.4e-71 238.0 0.1 1.5e-37 128.8 0.0 3.4 2 1 1 3 3 3 3 MCM P-loop domain MCM_lid PF17855.1 CRK35171.1 - 3.1e-42 142.9 9.4 1.4e-20 73.5 1.4 2.6 2 0 0 2 2 2 2 MCM AAA-lid domain MCM_OB PF17207.3 CRK35171.1 - 1.6e-29 102.3 1.0 2.9e-29 101.5 1.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_N PF14551.6 CRK35171.1 - 1.5e-15 57.6 0.8 1.5e-15 57.6 0.8 2.0 3 0 0 3 3 1 1 MCM N-terminal domain AAA_lid_2 PF17863.1 CRK35171.1 - 4.1e-06 26.6 0.5 0.15 11.9 0.1 2.7 2 0 0 2 2 2 2 AAA lid domain Mg_chelatase_C PF13335.6 CRK35171.1 - 3.3e-05 24.4 3.8 0.22 12.2 0.3 2.9 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI C-terminal DUF1184 PF06683.11 CRK35171.1 - 5e-05 22.9 0.0 0.54 9.7 0.0 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF1184) MCM_bind PF09739.9 CRK35171.1 - 0.0056 15.2 0.4 3 6.2 0.0 2.6 2 0 0 2 2 2 2 Mini-chromosome maintenance replisome factor AAA_5 PF07728.14 CRK35171.1 - 0.019 15.0 0.0 0.062 13.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) SgrR_N PF12793.7 CRK35171.1 - 0.024 14.9 0.3 13 6.0 0.0 2.6 2 0 0 2 2 2 0 Sugar transport-related sRNA regulator N-term PBP1_TM PF14812.6 CRK35171.1 - 5.1 7.5 7.5 7 7.1 1.3 3.3 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TPR_21 PF09976.9 CRK35171.1 - 8.5 6.0 9.2 15 5.2 0.7 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat-like domain AAA PF00004.29 CRK35172.1 - 5.2e-99 327.8 0.0 4.8e-42 143.5 0.0 4.4 4 0 0 4 4 4 4 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 CRK35172.1 - 6e-37 125.9 0.9 1.2e-26 93.0 0.1 2.9 2 0 0 2 2 2 2 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.6 CRK35172.1 - 7.6e-20 72.0 10.4 0.00024 21.5 0.2 7.2 4 3 2 6 6 6 4 AAA ATPase domain AAA_lid_3 PF17862.1 CRK35172.1 - 1.5e-16 59.9 0.1 4e-06 26.5 0.0 3.7 3 0 0 3 3 3 3 AAA+ lid domain NACHT PF05729.12 CRK35172.1 - 4.2e-13 49.5 6.1 3.9e-05 23.6 0.0 5.7 6 0 0 6 6 5 2 NACHT domain AAA_18 PF13238.6 CRK35172.1 - 8.7e-13 48.9 0.4 0.066 13.8 0.0 4.8 4 0 0 4 4 4 2 AAA domain AAA_2 PF07724.14 CRK35172.1 - 1.1e-12 48.4 0.0 0.032 14.4 0.0 4.5 4 0 0 4 4 4 3 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 CRK35172.1 - 1.2e-12 48.3 5.3 0.1 12.8 0.0 6.7 4 2 1 5 5 5 2 AAA domain AAA_33 PF13671.6 CRK35172.1 - 3.1e-12 46.8 0.2 0.28 11.3 0.0 4.9 4 0 0 4 4 4 4 AAA domain AAA_7 PF12775.7 CRK35172.1 - 5.7e-12 45.5 0.3 0.00064 19.3 0.0 4.0 4 0 0 4 4 4 2 P-loop containing dynein motor region RuvB_N PF05496.12 CRK35172.1 - 6.9e-12 45.4 0.0 0.019 14.7 0.0 4.4 4 0 0 4 4 4 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CRK35172.1 - 2.4e-11 43.8 0.5 0.26 11.3 0.0 4.9 4 2 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 CRK35172.1 - 7.2e-11 42.2 0.0 0.35 10.9 0.0 4.5 4 0 0 4 4 4 4 AAA domain AAA_25 PF13481.6 CRK35172.1 - 6.1e-10 39.0 2.9 2.3 7.8 0.1 6.6 6 1 0 6 6 6 2 AAA domain RNA_helicase PF00910.22 CRK35172.1 - 3.4e-09 37.1 0.0 2.3 8.6 0.0 4.7 4 0 0 4 4 4 2 RNA helicase IstB_IS21 PF01695.17 CRK35172.1 - 1.1e-08 35.0 1.1 1.1 8.9 0.0 4.4 4 0 0 4 4 4 2 IstB-like ATP binding protein TsaE PF02367.17 CRK35172.1 - 4.1e-08 33.3 0.2 5.1 7.1 0.0 4.6 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 CRK35172.1 - 5.2e-08 32.5 0.1 2 7.5 0.0 4.3 4 0 0 4 4 4 2 TIP49 P-loop domain ABC_tran PF00005.27 CRK35172.1 - 2e-07 31.6 0.1 4.6 7.8 0.0 4.8 4 0 0 4 4 4 0 ABC transporter Zeta_toxin PF06414.12 CRK35172.1 - 2.1e-07 30.5 1.4 1.5 8.0 0.0 4.4 4 0 0 4 4 4 2 Zeta toxin Mg_chelatase PF01078.21 CRK35172.1 - 1.1e-06 28.1 1.1 1.4 8.3 0.1 4.6 4 0 0 4 4 4 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 CRK35172.1 - 1.6e-06 27.9 0.0 1.3 8.7 0.0 4.5 4 0 0 4 4 4 2 Sigma-54 interaction domain AAA_28 PF13521.6 CRK35172.1 - 2.8e-06 27.7 0.5 8.7 6.6 0.0 4.7 4 0 0 4 4 4 0 AAA domain AAA_17 PF13207.6 CRK35172.1 - 3.1e-06 27.6 3.1 4.4 7.7 0.1 4.8 4 0 0 4 4 4 0 AAA domain SKI PF01202.22 CRK35172.1 - 1.6e-05 25.1 0.2 13 5.9 0.0 4.5 4 0 0 4 4 4 0 Shikimate kinase Sigma54_activ_2 PF14532.6 CRK35172.1 - 2.6e-05 24.4 0.0 8.9 6.4 0.0 4.5 4 0 0 4 4 4 0 Sigma-54 interaction domain NTPase_1 PF03266.15 CRK35172.1 - 3e-05 24.0 0.2 1.6 8.6 0.0 3.9 4 0 0 4 4 4 2 NTPase ATPase_2 PF01637.18 CRK35172.1 - 5.2e-05 23.3 0.2 4.8 7.0 0.0 4.4 4 0 0 4 4 4 0 ATPase domain predominantly from Archaea Rad17 PF03215.15 CRK35172.1 - 7e-05 22.8 0.0 5.4 6.9 0.0 4.2 4 0 0 4 4 4 0 Rad17 P-loop domain AAA_29 PF13555.6 CRK35172.1 - 8.3e-05 22.3 2.7 1.2 8.9 0.4 3.9 4 0 0 4 4 4 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CRK35172.1 - 9.1e-05 22.4 0.2 0.79 9.6 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase DUF2075 PF09848.9 CRK35172.1 - 0.0001 21.7 0.0 15 4.7 0.0 4.3 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2075) Cytidylate_kin2 PF13189.6 CRK35172.1 - 0.00012 22.3 0.1 10 6.2 0.0 4.4 4 0 0 4 4 4 0 Cytidylate kinase-like family APS_kinase PF01583.20 CRK35172.1 - 0.00013 21.9 4.1 0.36 10.7 0.0 3.4 4 0 0 4 4 2 2 Adenylylsulphate kinase AAA_24 PF13479.6 CRK35172.1 - 0.00018 21.3 3.6 14 5.3 0.0 4.3 4 0 0 4 4 4 0 AAA domain Viral_helicase1 PF01443.18 CRK35172.1 - 0.00022 21.0 0.0 3.6 7.3 0.0 3.9 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase PRK PF00485.18 CRK35172.1 - 0.00027 20.7 0.5 1.1 8.9 0.1 2.7 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family ATPase PF06745.13 CRK35172.1 - 0.00061 19.2 0.0 23 4.2 0.0 4.4 4 0 0 4 4 4 0 KaiC Cytidylate_kin PF02224.18 CRK35172.1 - 0.0011 18.7 0.0 2.2 8.0 0.0 2.6 2 0 0 2 2 2 2 Cytidylate kinase AAA_19 PF13245.6 CRK35172.1 - 0.0014 18.9 0.5 12 6.2 0.0 4.1 4 0 0 4 4 4 0 AAA domain CPT PF07931.12 CRK35172.1 - 0.0016 18.3 0.0 3.2 7.6 0.0 2.7 2 0 0 2 2 2 2 Chloramphenicol phosphotransferase-like protein NB-ARC PF00931.22 CRK35172.1 - 0.002 17.4 1.6 22 4.1 0.0 4.5 5 0 0 5 5 4 0 NB-ARC domain AAA_3 PF07726.11 CRK35172.1 - 0.0022 17.8 0.0 12 5.8 0.0 3.9 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) PEX-2N PF09263.10 CRK35172.1 - 0.0029 17.9 0.0 2.5 8.5 0.0 3.0 2 0 0 2 2 2 1 Peroxisome biogenesis factor 1, N-terminal DUF815 PF05673.13 CRK35172.1 - 0.004 16.3 1.5 6.6 5.8 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF815) KAP_NTPase PF07693.14 CRK35172.1 - 0.0071 15.6 2.2 3.5 6.8 0.1 3.1 2 1 1 3 3 3 1 KAP family P-loop domain AAA_30 PF13604.6 CRK35172.1 - 0.008 15.9 1.7 9.5 5.9 0.0 3.9 4 0 0 4 4 4 0 AAA domain PhoH PF02562.16 CRK35172.1 - 0.018 14.5 0.7 76 2.6 0.1 4.1 4 0 0 4 4 4 0 PhoH-like protein Thymidylate_kin PF02223.17 CRK35172.1 - 0.056 13.1 0.0 16 5.1 0.0 2.6 2 0 0 2 2 2 0 Thymidylate kinase Zot PF05707.12 CRK35172.1 - 0.08 12.6 0.0 52 3.4 0.0 4.0 4 0 0 4 4 4 0 Zonular occludens toxin (Zot) RNA_pol_A_bac PF01000.26 CRK35173.1 - 1.7e-24 86.4 0.0 3.3e-24 85.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 CRK35173.1 - 1.1e-19 69.6 0.0 1.9e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain COXG PF06240.13 CRK35173.1 - 0.035 13.8 0.0 2 8.1 0.0 2.4 2 0 0 2 2 2 0 Carbon monoxide dehydrogenase subunit G (CoxG) ThiF PF00899.21 CRK35174.1 - 1.7e-63 214.3 0.1 2.3e-63 213.8 0.1 1.3 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 CRK35174.1 - 5.4e-32 109.8 0.4 8.7e-32 109.1 0.4 1.3 1 0 0 1 1 1 1 E2 binding domain UAE_UbL PF14732.6 CRK35174.1 - 0.00019 22.0 0.2 0.0034 17.9 0.0 2.5 3 0 0 3 3 3 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Shikimate_DH PF01488.20 CRK35174.1 - 0.00024 21.2 0.4 0.00063 19.8 0.1 1.9 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 CRK35174.1 - 0.028 14.9 0.0 0.069 13.6 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 CRK35174.1 - 0.056 13.7 0.0 0.17 12.1 0.0 1.9 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Pyr_redox PF00070.27 CRK35174.1 - 0.13 12.8 0.0 0.3 11.7 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CRK35174.1 - 0.28 11.2 0.5 18 5.3 0.0 2.7 2 1 1 3 3 3 0 FAD-NAD(P)-binding UBA_e1_thiolCys PF10585.9 CRK35174.1 - 0.58 10.0 2.2 22 4.9 0.0 2.3 1 1 0 2 2 2 0 Ubiquitin-activating enzyme active site Telomere_reg-2 PF10193.9 CRK35175.1 - 2e-34 118.3 0.0 1e-33 116.0 0.0 2.2 2 0 0 2 2 2 1 Telomere length regulation protein Telomere_reg-2 PF10193.9 CRK35176.1 - 3.1e-27 95.2 0.0 1.4e-26 93.0 0.0 2.2 2 0 0 2 2 2 1 Telomere length regulation protein ThiF PF00899.21 CRK35177.1 - 1.7e-63 214.2 0.1 2.6e-63 213.6 0.1 1.2 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 CRK35177.1 - 1.3e-32 111.7 0.3 2.1e-32 111.1 0.3 1.3 1 0 0 1 1 1 1 E2 binding domain Shikimate_DH PF01488.20 CRK35177.1 - 0.00027 21.0 0.5 0.00074 19.6 0.0 1.8 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase UAE_UbL PF14732.6 CRK35177.1 - 0.00047 20.7 0.0 0.0082 16.7 0.0 2.4 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Sacchrp_dh_NADP PF03435.18 CRK35177.1 - 0.038 14.3 0.0 0.1 12.9 0.0 1.8 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 CRK35177.1 - 0.059 13.8 0.0 0.14 12.6 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox PF00070.27 CRK35177.1 - 0.13 12.9 0.0 0.29 11.7 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UBA_e1_thiolCys PF10585.9 CRK35177.1 - 0.61 10.0 2.3 20 5.0 0.0 2.3 1 1 1 2 2 2 0 Ubiquitin-activating enzyme active site RNA_pol_A_bac PF01000.26 CRK35178.1 - 1.4e-24 86.6 0.0 3.1e-24 85.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 CRK35178.1 - 7e-20 70.2 0.0 1.3e-19 69.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain BTB_2 PF02214.22 CRK35179.1 - 0.00057 20.2 0.0 0.001 19.4 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain p450 PF00067.22 CRK35180.1 - 1.8e-10 40.2 0.0 2.3e-08 33.3 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Antimicrobial14 PF08109.11 CRK35181.1 - 0.052 13.6 1.2 12 6.0 1.0 2.3 2 0 0 2 2 2 0 Lactocin 705 family PEPCK_ATP PF01293.20 CRK35182.1 - 8.7e-193 641.2 0.0 1.1e-192 640.9 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_16 PF13191.6 CRK35182.1 - 0.027 14.9 0.0 0.043 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 CRK35182.1 - 0.13 12.5 0.1 0.27 11.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain GTP_EFTU_D3 PF03143.17 CRK35183.1 - 2.5e-26 92.2 0.0 3.3e-26 91.8 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain Ran-binding PF05508.11 CRK35184.1 - 4.2e-111 370.9 0.0 5.9e-111 370.4 0.0 1.2 1 0 0 1 1 1 1 RanGTP-binding protein Glyco_hydro_18 PF00704.28 CRK35192.1 - 7.6e-80 269.0 0.0 9.3e-80 268.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 PepX_C PF08530.10 CRK35192.1 - 0.072 13.0 0.0 2.2 8.2 0.0 2.2 1 1 1 2 2 2 0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Porin_3 PF01459.22 CRK35193.1 - 1.2e-15 57.8 0.0 1.4e-15 57.6 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic porin peroxidase PF00141.23 CRK35199.1 - 4.2e-40 137.9 0.0 8e-40 136.9 0.0 1.4 1 0 0 1 1 1 1 Peroxidase TT_ORF1 PF02956.14 CRK35201.1 - 1.9 7.1 12.6 2 7.0 12.6 1.0 1 0 0 1 1 1 0 TT viral orf 1 KAsynt_C_assoc PF16197.5 CRK35204.1 - 4e-19 69.1 0.0 5.1e-19 68.8 0.0 1.1 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension TYW3 PF02676.14 CRK35206.1 - 3.5e-73 245.5 0.0 4.7e-73 245.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase TYW3 DUF1690 PF07956.11 CRK35207.1 - 2.4e-42 144.7 4.2 2.8e-42 144.4 4.2 1.0 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) FUSC PF04632.12 CRK35207.1 - 0.097 11.2 5.9 0.11 11.1 5.9 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Ferric_reduct PF01794.19 CRK35208.1 - 2.2e-23 82.7 14.5 4.7e-23 81.7 10.1 2.6 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 CRK35208.1 - 7.4e-13 48.9 0.0 4e-05 23.8 0.0 2.2 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 CRK35208.1 - 2.2e-06 27.7 0.0 5.1e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Synapsin_N PF10581.9 CRK35208.1 - 0.045 13.7 0.6 1.1 9.2 0.3 2.5 2 0 0 2 2 2 0 Synapsin N-terminal DUF5122 PF17164.4 CRK35213.1 - 0.0053 17.0 0.9 0.36 11.2 0.2 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF5122) beta-propeller DUF2964 PF11177.8 CRK35213.1 - 0.12 12.6 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2964) ETC_C1_NDUFA4 PF04800.12 CRK35217.1 - 2.7e-27 94.8 0.3 2.9e-27 94.7 0.3 1.0 1 0 0 1 1 1 1 ETC complex I subunit conserved region MucBP_2 PF17965.1 CRK35217.1 - 0.1 13.2 0.0 0.11 13.0 0.0 1.1 1 0 0 1 1 1 0 Mucin binding domain Ribosomal_L27e PF01777.18 CRK35220.1 - 5.1e-36 122.9 2.9 6e-36 122.7 2.9 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family PAPA-1 PF04795.12 CRK35227.1 - 2.9e-27 95.3 7.7 2.9e-27 95.3 7.7 4.9 4 2 1 6 6 6 1 PAPA-1-like conserved region Vps51 PF08700.11 CRK35228.1 - 3.8e-27 94.2 0.0 3.8e-27 94.2 0.0 2.1 2 0 0 2 2 2 1 Vps51/Vps67 SUIM_assoc PF16619.5 CRK35228.1 - 0.0035 17.4 3.3 0.0086 16.1 3.3 1.7 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 COG5 PF10392.9 CRK35228.1 - 0.0046 17.1 0.2 0.0046 17.1 0.2 2.4 2 1 0 2 2 2 1 Golgi transport complex subunit 5 S-AdoMet_synt_N PF00438.20 CRK35228.1 - 0.045 14.4 1.8 6 7.6 0.0 2.5 1 1 1 2 2 2 0 S-adenosylmethionine synthetase, N-terminal domain NmrA PF05368.13 CRK35229.1 - 4e-23 82.2 0.0 4.9e-23 81.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 CRK35229.1 - 2.1e-07 31.0 0.1 4.2e-07 30.0 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 CRK35229.1 - 0.074 13.0 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 KR domain RMI1_N PF08585.12 CRK35230.1 - 7.1e-56 189.4 0.0 8.2e-56 189.2 0.0 1.0 1 0 0 1 1 1 1 RecQ mediated genome instability protein TPR_16 PF13432.6 CRK35231.1 - 1.5e-28 99.1 48.9 6.7e-07 29.9 0.5 12.4 12 1 1 13 13 11 7 Tetratricopeptide repeat TPR_19 PF14559.6 CRK35231.1 - 1.4e-22 80.0 28.4 0.00019 21.9 2.0 9.9 8 2 1 9 9 9 5 Tetratricopeptide repeat TPR_2 PF07719.17 CRK35231.1 - 3e-22 76.9 44.2 0.013 15.6 0.0 14.3 16 0 0 16 16 15 7 Tetratricopeptide repeat TPR_17 PF13431.6 CRK35231.1 - 3.5e-22 77.1 17.3 0.66 10.5 0.0 14.6 15 0 0 15 15 14 5 Tetratricopeptide repeat TPR_1 PF00515.28 CRK35231.1 - 4.1e-21 73.8 28.2 0.00016 21.4 0.0 12.5 12 0 0 12 12 12 4 Tetratricopeptide repeat TPR_12 PF13424.6 CRK35231.1 - 7.6e-17 61.4 41.5 0.0047 17.2 0.0 11.9 10 2 1 11 11 11 5 Tetratricopeptide repeat TPR_14 PF13428.6 CRK35231.1 - 8.9e-16 57.3 46.7 0.0087 16.8 1.1 15.1 11 6 6 17 17 14 5 Tetratricopeptide repeat TPR_8 PF13181.6 CRK35231.1 - 1.4e-14 52.9 39.6 0.0027 17.8 0.0 13.5 15 0 0 15 15 14 4 Tetratricopeptide repeat TPR_7 PF13176.6 CRK35231.1 - 7.1e-09 35.1 28.8 0.0056 16.6 0.0 11.8 12 1 1 13 13 11 2 Tetratricopeptide repeat TPR_11 PF13414.6 CRK35231.1 - 1.7e-06 27.6 32.5 0.17 11.6 2.4 10.5 12 0 0 12 12 11 3 TPR repeat ANAPC3 PF12895.7 CRK35231.1 - 5.2e-06 26.6 10.5 11 6.4 0.0 7.7 7 2 1 8 8 8 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_22 PF18833.1 CRK35231.1 - 0.00016 21.8 0.0 0.00058 19.9 0.0 2.0 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_20 PF14561.6 CRK35231.1 - 0.00035 20.8 12.0 1 9.8 0.1 6.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 CRK35231.1 - 0.0038 17.4 23.8 0.17 12.0 0.1 6.8 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_6 PF13174.6 CRK35231.1 - 0.012 16.2 37.4 0.2 12.3 0.0 13.3 17 0 0 17 17 13 0 Tetratricopeptide repeat ChAPs PF09295.10 CRK35231.1 - 0.027 13.5 1.1 7.4 5.5 0.2 3.4 4 0 0 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) DUF3517 PF12030.8 CRK35231.1 - 0.038 12.9 0.0 0.067 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3517) Coatomer_WDAD PF04053.14 CRK35231.1 - 0.075 12.1 0.0 0.19 10.7 0.0 1.6 1 0 0 1 1 1 0 Coatomer WD associated region Anillin PF08174.11 CRK35233.1 - 5.5e-05 23.6 0.0 5.8e-05 23.6 0.0 1.0 1 0 0 1 1 1 1 Cell division protein anillin Peptidase_M3 PF01432.20 CRK35235.1 - 1.7e-19 70.5 0.1 1.8e-19 70.3 0.1 1.0 1 0 0 1 1 1 1 Peptidase family M3 Glyco_hydro_15 PF00723.21 CRK35236.1 - 1.7e-10 40.3 0.0 2e-10 40.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 GTP_cyclohydroI PF01227.22 CRK35237.1 - 7.6e-42 142.8 1.0 8.3e-42 142.6 1.0 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 CRK35237.1 - 0.0005 20.2 0.0 0.00071 19.7 0.0 1.2 1 0 0 1 1 1 1 QueF-like protein DUF3638 PF12340.8 CRK35237.1 - 0.0085 15.5 0.1 0.009 15.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) OmpH PF03938.14 CRK35237.1 - 0.071 13.4 0.0 0.081 13.3 0.0 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Transposase_20 PF02371.16 CRK35237.1 - 0.1 12.9 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Transposase IS116/IS110/IS902 family JAB PF01398.21 CRK35238.1 - 1.7e-30 105.4 0.4 9.8e-30 103.0 0.1 2.0 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 CRK35238.1 - 6.3e-23 81.5 0.0 1.2e-22 80.6 0.0 1.5 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 CRK35238.1 - 1.1e-05 25.2 0.0 6.7e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain GGACT PF06094.12 CRK35239.1 - 3e-12 47.2 0.0 3.5e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like MFS_1 PF07690.16 CRK35241.1 - 1.6e-25 89.8 32.2 2.3e-25 89.3 32.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3328 PF11807.8 CRK35242.1 - 2.1e-43 148.6 0.3 3.4e-43 148.0 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF5429 PF17494.2 CRK35245.1 - 0.14 12.3 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5429) DUF3361 PF11841.8 CRK35247.1 - 1.6e-07 31.4 0.0 2.3e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) Pkinase PF00069.25 CRK35252.1 - 1.8e-10 40.7 0.0 2.4e-07 30.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CRK35252.1 - 2.6e-06 26.9 0.0 0.022 14.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Choline_kinase PF01633.20 CRK35252.1 - 0.0017 18.0 0.0 0.0026 17.4 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 CRK35252.1 - 0.0026 17.7 0.0 0.0053 16.7 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CRK35252.1 - 0.095 12.0 0.1 0.17 11.2 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-C2H2_2 PF12756.7 CRK35253.1 - 1.4e-22 79.9 6.6 4.5e-21 75.1 3.3 2.4 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) SUZ-C PF12901.7 CRK35253.1 - 0.039 14.0 0.5 5 7.2 0.0 3.3 3 0 0 3 3 3 0 SUZ-C motif FAM176 PF14851.6 CRK35253.1 - 0.47 10.1 6.3 1.7 8.3 0.9 2.9 3 0 0 3 3 3 0 FAM176 family zf-C2H2_4 PF13894.6 CRK35253.1 - 4.3 8.5 11.4 18 6.5 0.1 4.2 4 0 0 4 4 4 0 C2H2-type zinc finger PBP1_TM PF14812.6 CRK35253.1 - 5.1 7.5 11.2 0.27 11.6 5.0 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Selenoprotein_S PF06936.11 CRK35254.1 - 0.041 13.7 0.4 0.057 13.2 0.4 1.2 1 0 0 1 1 1 0 Selenoprotein S (SelS) Voldacs PF03517.13 CRK35255.1 - 7.4e-22 78.0 0.5 7.6e-21 74.7 0.5 2.1 1 1 0 1 1 1 1 Regulator of volume decrease after cellular swelling Phage_holin_2_4 PF16082.5 CRK35256.1 - 0.0067 16.1 0.4 0.015 15.0 0.4 1.5 1 0 0 1 1 1 1 Bacteriophage holin family, superfamily II-like LSM PF01423.22 CRK35257.1 - 4.7e-16 58.2 0.2 6.3e-16 57.8 0.2 1.2 1 0 0 1 1 1 1 LSM domain DUF1656 PF07869.12 CRK35258.1 - 0.15 12.1 0.1 0.23 11.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) ABC_tran PF00005.27 CRK35260.1 - 2.9e-16 60.2 0.0 3.2e-16 60.1 0.0 1.0 1 0 0 1 1 1 1 ABC transporter Sugar_tr PF00083.24 CRK35262.1 - 4.4e-16 58.8 0.3 4.8e-16 58.7 0.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK35262.1 - 0.0013 17.8 0.8 0.0013 17.8 0.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily FAD_binding_4 PF01565.23 CRK35263.1 - 6.8e-22 77.7 0.3 8.6e-22 77.4 0.3 1.1 1 0 0 1 1 1 1 FAD binding domain TPR_12 PF13424.6 CRK35264.1 - 0.00045 20.4 0.2 0.015 15.6 0.0 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_MalT PF17874.1 CRK35264.1 - 0.0036 16.7 0.1 0.0043 16.5 0.1 1.0 1 0 0 1 1 1 1 MalT-like TPR region DUF3856 PF12968.7 CRK35264.1 - 0.025 14.7 0.1 0.039 14.0 0.1 1.4 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) TPR_2 PF07719.17 CRK35264.1 - 0.061 13.5 0.0 18 5.8 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat SPDY PF03771.16 CRK35265.1 - 3.7 7.5 7.7 1.7 8.6 2.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF317) Rad51 PF08423.11 CRK35267.1 - 3e-98 328.2 0.3 3.3e-98 328.0 0.3 1.0 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 CRK35267.1 - 2.7e-09 36.9 0.0 3.3e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 CRK35267.1 - 2.7e-08 33.6 0.0 3.7e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 CRK35267.1 - 5.3e-06 26.0 0.1 9.2e-06 25.2 0.1 1.4 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.15 CRK35267.1 - 0.005 16.2 0.2 0.05 12.9 0.0 2.0 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain PAXNEB PF05625.11 CRK35267.1 - 0.0059 15.8 2.7 0.036 13.2 0.9 2.1 1 1 1 2 2 2 1 PAXNEB protein AAA_22 PF13401.6 CRK35267.1 - 0.035 14.4 0.2 0.099 12.9 0.2 1.6 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CRK35267.1 - 0.04 13.6 0.0 0.067 12.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain YTH PF04146.15 CRK35268.1 - 1.4e-63 213.7 0.4 4.2e-63 212.2 0.0 1.8 2 0 0 2 2 2 1 YT521-B-like domain RRM_1 PF00076.22 CRK35268.1 - 0.006 16.4 0.0 0.017 14.9 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Proteasome PF00227.26 CRK35269.1 - 4.4e-24 85.0 1.4 4.9e-24 84.9 0.2 1.6 2 1 0 2 2 2 1 Proteasome subunit Aminotran_3 PF00202.21 CRK35271.1 - 2.7e-05 23.0 0.0 3.2e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Ribosomal_S7e PF01251.18 CRK35272.1 - 1.8e-51 174.6 0.6 1.9e-51 174.4 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Complex1_LYR PF05347.15 CRK35277.1 - 5.2e-12 45.6 2.1 6.6e-12 45.3 0.0 2.2 2 0 0 2 2 2 1 Complex 1 protein (LYR family) bZIP_1 PF00170.21 CRK35277.1 - 7.6e-06 25.9 5.2 1.8e-05 24.8 5.2 1.6 1 0 0 1 1 1 1 bZIP transcription factor Complex1_LYR_2 PF13233.6 CRK35277.1 - 0.054 14.2 0.1 0.2 12.4 0.1 2.0 1 0 0 1 1 1 0 Complex1_LYR-like His_binding PF02098.16 CRK35277.1 - 0.28 11.2 1.2 0.55 10.2 1.2 1.4 1 0 0 1 1 1 0 Tick histamine binding protein tRNA-synt_1e PF01406.19 CRK35279.1 - 3.3e-19 69.3 0.0 3.7e-19 69.2 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1c PF00749.21 CRK35279.1 - 0.032 13.1 0.0 0.032 13.1 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain DUF1990 PF09348.10 CRK35279.1 - 0.17 11.9 0.0 0.27 11.3 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1990) DUF5597 PF18120.1 CRK35280.1 - 3.1e-17 62.9 0.2 3.4e-17 62.8 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF5597) CPSF_A PF03178.15 CRK35281.1 - 5.2e-27 95.0 0.0 5.7e-27 94.9 0.0 1.0 1 0 0 1 1 1 1 CPSF A subunit region YmzC PF14157.6 CRK35281.1 - 0.079 13.0 0.2 0.14 12.2 0.2 1.4 1 0 0 1 1 1 0 YmzC-like protein Cupin_2 PF07883.11 CRK35283.1 - 4.2e-08 32.8 0.2 8.4e-08 31.8 0.0 1.6 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.22 CRK35283.1 - 0.0089 15.6 0.0 0.012 15.3 0.0 1.1 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 CRK35283.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) PGM_PMM_III PF02880.16 CRK35284.1 - 4.1e-42 143.0 0.0 1.5e-25 89.6 0.0 2.4 2 0 0 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 CRK35284.1 - 1.4e-12 47.6 0.0 0.0001 22.4 0.0 2.6 2 0 0 2 2 2 2 Phosphoglucomutase/phosphomannomutase, C-terminal domain RCC1_2 PF13540.6 CRK35284.1 - 0.0028 17.4 0.0 4.7 7.1 0.0 2.8 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat PqqD PF05402.12 CRK35284.1 - 0.026 14.8 0.0 15 6.0 0.0 2.5 2 0 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) DUF1966 PF09260.11 CRK35284.1 - 0.033 14.4 0.3 14 6.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1966) Lipoprotein_1 PF00820.19 CRK35284.1 - 0.036 13.1 0.0 8.1 5.4 0.0 2.2 2 0 0 2 2 2 0 Borrelia lipoprotein DUF2016 PF09436.10 CRK35284.1 - 0.055 13.3 0.2 19 5.1 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2016) ThiF PF00899.21 CRK35287.1 - 6.2e-20 71.6 0.0 7e-20 71.4 0.0 1.0 1 0 0 1 1 1 1 ThiF family Sec3-PIP2_bind PF15277.6 CRK35305.1 - 2.7e-22 78.7 0.1 3.1e-22 78.5 0.1 1.1 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH AAA PF00004.29 CRK35315.1 - 1.8e-15 57.6 0.0 4e-15 56.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 CRK35315.1 - 0.00015 21.2 0.0 0.00027 20.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 CRK35315.1 - 0.00074 19.8 0.2 0.0021 18.4 0.2 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CRK35315.1 - 0.0012 19.2 0.5 0.0053 17.2 0.5 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 CRK35315.1 - 0.0026 17.7 0.2 0.0093 16.0 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) DnaB_C PF03796.15 CRK35315.1 - 0.028 13.7 0.0 0.051 12.9 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Mg_chelatase PF01078.21 CRK35315.1 - 0.034 13.5 0.0 0.08 12.3 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 CRK35315.1 - 0.045 14.3 0.0 0.13 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 CRK35315.1 - 0.09 12.2 0.2 0.15 11.5 0.2 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 NACHT PF05729.12 CRK35315.1 - 0.14 12.1 0.1 0.42 10.5 0.1 1.8 1 1 0 1 1 1 0 NACHT domain Zeta_toxin PF06414.12 CRK35315.1 - 0.14 11.5 0.0 0.26 10.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Zot PF05707.12 CRK35315.1 - 0.18 11.4 0.0 0.53 9.9 0.0 1.8 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) ATPase PF06745.13 CRK35315.1 - 0.48 9.7 1.3 0.74 9.1 0.2 1.8 2 0 0 2 2 2 0 KaiC CBM_1 PF00734.18 CRK35317.1 - 7.8e-12 44.9 15.6 1.4e-11 44.1 15.6 1.5 1 0 0 1 1 1 1 Fungal cellulose binding domain Scytalone_dh PF02982.14 CRK35317.1 - 1.2e-08 34.9 0.0 1.7e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.6 CRK35317.1 - 1.1e-05 25.5 0.1 1.6e-05 25.0 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain Pertussis_S1 PF02917.14 CRK35317.1 - 0.033 14.0 0.0 0.051 13.3 0.0 1.2 1 0 0 1 1 1 0 Pertussis toxin, subunit 1 Toxin_7 PF05980.12 CRK35317.1 - 0.058 13.6 8.4 0.12 12.7 8.4 1.6 1 1 0 1 1 1 0 Toxin 7 NTP_transf_6 PF06042.11 CRK35319.1 - 9.2e-53 178.3 0.0 1.1e-52 178.1 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyltransferase SDF PF00375.18 CRK35321.1 - 2.4e-87 293.5 33.0 2.8e-87 293.3 33.0 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family DIOX_N PF14226.6 CRK35323.1 - 5.2e-26 91.7 0.1 8.3e-26 91.1 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 CRK35323.1 - 4.3e-22 78.5 0.0 1.1e-21 77.2 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PDEase_I_N PF08499.12 CRK35323.1 - 0.14 12.0 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal Polysacc_deac_1 PF01522.21 CRK35326.1 - 2.5e-26 92.0 0.0 4e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 CRK35326.1 - 0.033 13.4 0.0 0.047 12.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 DUF966 PF06136.13 CRK35326.1 - 5.1 6.7 9.4 7.5 6.2 9.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) ATG11 PF10377.9 CRK35328.1 - 8.7e-47 158.4 0.1 8.7e-47 158.4 0.1 3.8 5 0 0 5 5 5 1 Autophagy-related protein 11 ERM PF00769.19 CRK35328.1 - 0.00049 20.0 22.8 0.00049 20.0 22.8 5.1 3 1 2 5 5 5 1 Ezrin/radixin/moesin family GAS PF13851.6 CRK35328.1 - 0.0094 15.3 3.0 0.0094 15.3 3.0 6.0 2 1 4 6 6 6 2 Growth-arrest specific micro-tubule binding Filament PF00038.21 CRK35328.1 - 0.01 15.5 13.2 0.01 15.5 13.2 4.7 2 1 2 4 4 4 0 Intermediate filament protein BST2 PF16716.5 CRK35328.1 - 0.012 16.2 7.3 0.012 16.2 7.3 7.1 5 3 2 7 7 7 0 Bone marrow stromal antigen 2 GP57 PF17594.2 CRK35328.1 - 0.033 13.9 1.5 12 5.7 0.4 3.2 2 0 0 2 2 2 0 Phage Tail fiber assembly helper gene product 57 Gal4_dimer PF03902.13 CRK35328.1 - 0.051 13.7 1.4 16 5.8 0.1 3.2 2 0 0 2 2 2 0 Gal4-like dimerisation domain FERM_f0 PF16511.5 CRK35328.1 - 0.079 13.3 0.0 0.24 11.7 0.0 1.8 1 0 0 1 1 1 0 N-terminal or F0 domain of Talin-head FERM Bacillus_HBL PF05791.11 CRK35328.1 - 0.8 9.5 26.8 0.28 11.0 2.2 5.4 3 2 2 5 5 5 0 Bacillus haemolytic enterotoxin (HBL) HOOK PF05622.12 CRK35328.1 - 3.3 5.7 63.9 0.081 11.1 56.2 1.9 2 0 0 2 2 2 0 HOOK protein Polysacc_deac_1 PF01522.21 CRK35330.1 - 8e-26 90.4 0.0 1.3e-25 89.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Med3 PF11593.8 CRK35330.1 - 0.0025 17.1 1.3 0.0025 17.1 1.3 2.2 2 0 0 2 2 2 1 Mediator complex subunit 3 fungal Baculo_E56 PF04639.12 CRK35330.1 - 0.13 11.5 0.1 0.35 10.1 0.0 1.7 2 0 0 2 2 2 0 Baculoviral E56 protein, specific to ODV envelope DUF4661 PF15576.6 CRK35330.1 - 1.1 9.1 3.1 1.9 8.4 3.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) DUF966 PF06136.13 CRK35330.1 - 3.6 7.2 10.6 5.4 6.6 10.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) ATG11 PF10377.9 CRK35332.1 - 3.7e-47 159.6 2.8 2.1e-46 157.1 0.1 3.3 2 0 0 2 2 2 1 Autophagy-related protein 11 FERM_f0 PF16511.5 CRK35332.1 - 3.1e-05 24.2 0.7 0.6 10.4 0.0 3.7 3 0 0 3 3 3 1 N-terminal or F0 domain of Talin-head FERM ERM PF00769.19 CRK35332.1 - 0.0012 18.7 23.1 0.0012 18.7 23.1 7.5 5 1 2 7 7 7 1 Ezrin/radixin/moesin family APG17 PF04108.12 CRK35332.1 - 0.0023 17.1 2.6 0.0023 17.1 2.6 7.0 3 2 1 4 4 4 2 Autophagy protein Apg17 Fez1 PF06818.15 CRK35332.1 - 0.0031 18.0 16.0 0.0031 18.0 16.0 9.6 6 3 3 9 9 9 1 Fez1 DNA_ligase_OB PF03120.16 CRK35332.1 - 0.0056 16.5 0.0 29 4.7 0.0 3.5 3 0 0 3 3 3 0 NAD-dependent DNA ligase OB-fold domain Phage_30_8 PF06019.11 CRK35332.1 - 0.065 13.1 0.2 26 4.7 0.0 3.1 2 0 0 2 2 2 0 Phage GP30.8 protein T3SS_needle_F PF09392.10 CRK35332.1 - 0.22 11.7 2.8 2.4 8.4 0.1 4.4 3 0 0 3 3 3 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF WD40_alt PF14077.6 CRK35332.1 - 0.67 9.9 3.7 47 4.0 0.2 4.2 3 0 0 3 3 3 0 Alternative WD40 repeat motif SpecificRecomb PF10136.9 CRK35332.1 - 8.1 4.6 16.1 21 3.2 16.1 1.7 1 0 0 1 1 1 0 Site-specific recombinase CENP-H PF05837.12 CRK35334.1 - 4.1e-34 117.4 0.4 1.3e-33 115.7 0.0 1.8 2 0 0 2 2 2 1 Centromere protein H (CENP-H) Fez1 PF06818.15 CRK35334.1 - 0.18 12.2 1.4 0.86 10.0 1.4 1.8 1 1 0 1 1 1 0 Fez1 GvpL_GvpF PF06386.11 CRK35334.1 - 0.74 9.7 7.2 0.58 10.0 5.1 1.6 1 1 1 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF DASH_Dad3 PF08656.10 CRK35334.1 - 0.88 9.7 3.1 16 5.6 0.3 2.6 2 1 0 2 2 2 0 DASH complex subunit Dad3 ATG16 PF08614.11 CRK35334.1 - 1.4 9.1 12.4 22 5.2 12.4 2.2 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) CENP-H PF05837.12 CRK35337.1 - 1.9e-33 115.2 0.1 6.7e-33 113.5 0.0 1.8 2 0 0 2 2 2 1 Centromere protein H (CENP-H) SBP_bac_3 PF00497.20 CRK35337.1 - 0.073 12.5 0.6 0.11 11.9 0.6 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 GvpL_GvpF PF06386.11 CRK35337.1 - 0.28 11.1 4.5 0.59 10.0 4.3 1.6 1 1 1 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF HMG_box PF00505.19 CRK35341.1 - 4.8e-46 155.0 5.6 1.4e-23 83.1 0.5 2.7 4 0 0 4 4 4 2 HMG (high mobility group) box HMG_box_2 PF09011.10 CRK35341.1 - 6.8e-34 116.3 7.0 5.7e-17 62.1 0.8 2.6 2 0 0 2 2 2 2 HMG-box domain Ccdc124 PF06244.12 CRK35341.1 - 2.1e-05 25.1 7.1 0.012 16.2 0.9 3.1 1 1 2 3 3 3 2 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box_5 PF14887.6 CRK35341.1 - 0.00014 21.7 3.2 0.09 12.8 0.1 2.7 2 0 0 2 2 2 2 HMG (high mobility group) box 5 DUF2582 PF10771.9 CRK35341.1 - 0.0013 18.9 0.4 1.5 9.0 0.1 2.3 2 0 0 2 2 2 2 Winged helix-turn-helix domain (DUF2582) CHDNT PF08073.12 CRK35341.1 - 0.013 15.5 0.0 0.21 11.6 0.0 2.5 2 0 0 2 2 2 0 CHDNT (NUC034) domain YABBY PF04690.13 CRK35341.1 - 0.014 15.9 6.2 0.62 10.6 1.3 2.2 1 1 1 2 2 2 0 YABBY protein RAMP4 PF06624.12 CRK35341.1 - 0.89 9.7 3.2 31 4.7 0.2 2.6 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 GFO_IDH_MocA_C PF02894.17 CRK35343.1 - 0.00014 21.8 0.0 0.00027 20.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain GFO_IDH_MocA PF01408.22 CRK35343.1 - 0.013 16.3 0.0 0.023 15.5 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold ImpA_N PF06812.12 CRK35343.1 - 0.018 15.2 0.0 0.035 14.2 0.0 1.5 1 0 0 1 1 1 0 ImpA, N-terminal, type VI secretion system Cupin_2 PF07883.11 CRK35344.1 - 9.8e-08 31.6 0.2 1.9e-07 30.7 0.0 1.6 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.22 CRK35344.1 - 0.011 15.3 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 Cupin 3Beta_HSD PF01073.19 CRK35347.1 - 3.2e-21 75.6 0.0 3.2e-20 72.3 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 CRK35347.1 - 4e-08 32.7 0.0 6.2e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 CRK35347.1 - 0.00017 21.1 0.0 0.00031 20.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 CRK35347.1 - 0.008 15.3 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 CRK35347.1 - 0.11 12.3 0.0 0.69 9.8 0.0 2.1 1 1 0 1 1 1 0 NAD(P)H-binding Sporozoite_P67 PF05642.11 CRK35349.1 - 0.019 13.1 7.2 0.021 12.9 7.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SUI1 PF01253.22 CRK35351.1 - 4.5e-28 97.6 2.5 5.7e-28 97.3 1.8 1.6 2 0 0 2 2 2 1 Translation initiation factor SUI1 SIL1 PF16782.5 CRK35353.1 - 9.5e-06 25.0 0.0 1.5e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Nucleotide exchange factor SIL1 DUF4381 PF14316.6 CRK35353.1 - 0.0024 18.1 0.4 0.0068 16.7 0.1 2.0 2 1 0 2 2 2 1 Domain of unknown function (DUF4381) DUF2076 PF09849.9 CRK35353.1 - 0.19 11.8 0.6 0.35 10.9 0.6 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Ribosomal_S19 PF00203.21 CRK35357.1 - 5.6e-33 112.7 0.2 9.5e-33 111.9 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S19 F-box PF00646.33 CRK35357.1 - 0.025 14.4 0.1 0.057 13.3 0.1 1.5 1 0 0 1 1 1 0 F-box domain Glutaredoxin PF00462.24 CRK35360.1 - 4.6e-05 23.6 0.2 0.00014 22.0 0.0 1.9 2 0 0 2 2 2 1 Glutaredoxin Serglycin PF04360.12 CRK35360.1 - 3.1 7.7 7.5 3.4 7.6 2.9 2.2 1 1 0 2 2 2 0 Serglycin GFA PF04828.14 CRK35364.1 - 7.7e-12 45.4 0.1 4.8e-05 23.6 0.1 2.3 2 0 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme DUF1765 PF08578.10 CRK35366.1 - 2.9e-47 160.2 2.1 6.4e-47 159.1 2.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) SBF PF01758.16 CRK35367.1 - 5.8e-49 166.4 13.5 1e-48 165.6 13.5 1.4 1 0 0 1 1 1 1 Sodium Bile acid symporter family PGM_PMM_I PF02878.16 CRK35370.1 - 5.2e-68 227.1 1.5 1.3e-32 112.4 0.0 3.1 4 0 0 4 4 4 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I RNase_T PF00929.24 CRK35370.1 - 4.8e-45 154.1 0.0 5.1e-21 75.9 0.0 2.5 2 0 0 2 2 2 2 Exonuclease Cys_Met_Meta_PP PF01053.20 CRK35370.1 - 3.3e-20 72.0 0.0 5.1e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme RuvX PF03652.15 CRK35370.1 - 0.0038 17.6 0.0 4.3 7.7 0.0 2.6 2 0 0 2 2 2 2 Holliday junction resolvase CC2D2AN-C2 PF15625.6 CRK35370.1 - 0.064 13.0 0.0 16 5.2 0.0 2.8 2 0 0 2 2 2 0 CC2D2A N-terminal C2 domain SnoaL_4 PF13577.6 CRK35370.1 - 0.13 12.4 0.0 25 5.0 0.0 2.5 2 0 0 2 2 2 0 SnoaL-like domain DUF3012 PF11216.8 CRK35370.1 - 2 8.5 3.9 40 4.3 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3012) GFO_IDH_MocA PF01408.22 CRK35373.1 - 1.7e-09 38.5 0.0 4.1e-09 37.3 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 CRK35373.1 - 0.00019 21.4 0.0 0.00038 20.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain ImpA_N PF06812.12 CRK35373.1 - 0.022 14.9 0.0 0.051 13.7 0.0 1.6 1 0 0 1 1 1 0 ImpA, N-terminal, type VI secretion system Cupin_2 PF07883.11 CRK35375.1 - 9.4e-08 31.7 0.2 1.9e-07 30.7 0.0 1.6 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.22 CRK35375.1 - 0.011 15.3 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 Cupin NLRC4_HD2 PF17776.1 CRK35377.1 - 0.043 14.4 0.2 0.068 13.7 0.2 1.3 1 0 0 1 1 1 0 NLRC4 helical domain HD2 3Beta_HSD PF01073.19 CRK35379.1 - 6.4e-27 94.3 0.0 6.2e-26 91.0 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 CRK35379.1 - 4.9e-10 39.0 0.1 4.6e-09 35.8 0.1 2.0 1 1 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 CRK35379.1 - 1.7e-09 37.5 0.0 3.7e-09 36.4 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 CRK35379.1 - 1.2e-05 24.7 0.0 2.2e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 CRK35379.1 - 0.00019 21.4 0.2 0.00052 20.0 0.2 1.7 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 CRK35379.1 - 0.00085 19.3 0.0 0.0055 16.6 0.0 2.1 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 CRK35379.1 - 0.023 14.1 0.0 0.039 13.4 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 CRK35379.1 - 0.11 12.7 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Sporozoite_P67 PF05642.11 CRK35381.1 - 0.39 8.8 7.7 0.41 8.7 7.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SUI1 PF01253.22 CRK35383.1 - 1.2e-06 28.9 0.1 1.6e-06 28.5 0.1 1.3 1 0 0 1 1 1 1 Translation initiation factor SUI1 Ribosomal_S19 PF00203.21 CRK35387.1 - 7.1e-34 115.5 0.2 1e-33 115.1 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 EpmC PF04315.12 CRK35387.1 - 0.12 12.1 0.0 4.2 7.0 0.0 2.1 2 0 0 2 2 2 0 Elongation factor P hydroxylase Glutaredoxin PF00462.24 CRK35389.1 - 0.00035 20.7 0.0 0.0012 19.0 0.0 2.0 1 0 0 1 1 1 1 Glutaredoxin GFA PF04828.14 CRK35393.1 - 1.3e-11 44.7 0.1 4.4e-05 23.7 0.1 2.2 2 0 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme DUF1765 PF08578.10 CRK35394.1 - 7.5e-47 158.9 2.1 1.6e-46 157.8 2.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) MAGI_u5 PF16666.5 CRK35394.1 - 3.4 7.8 12.8 0.92 9.7 7.5 2.6 2 1 0 2 2 2 0 Unstructured region on MAGI SBF PF01758.16 CRK35396.1 - 2.2e-49 167.8 14.2 4.1e-49 166.9 14.2 1.5 1 0 0 1 1 1 1 Sodium Bile acid symporter family Zn_clus PF00172.18 CRK35400.1 - 5.6e-08 32.8 10.3 9e-08 32.1 10.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Brix PF04427.18 CRK35402.1 - 8.9e-33 114.0 0.0 1.5e-32 113.3 0.0 1.4 1 0 0 1 1 1 1 Brix domain SUIM_assoc PF16619.5 CRK35405.1 - 0.0029 17.6 0.0 0.016 15.3 0.0 2.2 1 1 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 DUF4719 PF15843.5 CRK35405.1 - 0.029 14.5 1.2 0.057 13.5 1.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4719) Sds3 PF08598.11 CRK35405.1 - 0.029 14.4 0.2 0.04 13.9 0.2 1.4 1 1 0 1 1 1 0 Sds3-like DUF1180 PF06679.12 CRK35405.1 - 6.1 7.2 11.8 13 6.1 11.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) RRM_1 PF00076.22 CRK35406.1 - 2e-09 37.1 0.0 3.9e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_pol_Rpc4 PF05132.14 CRK35406.1 - 3.9 7.9 7.7 2.3 8.7 5.5 1.9 2 1 0 2 2 2 0 RNA polymerase III RPC4 Tubulin PF00091.25 CRK35408.1 - 1.3e-63 214.8 0.0 1.7e-63 214.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CRK35408.1 - 7.3e-44 149.0 0.0 1.1e-43 148.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CRK35408.1 - 8.9e-05 22.2 0.0 0.00015 21.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Coiled-coil_56 PF09813.9 CRK35410.1 - 0.011 15.7 0.0 0.012 15.6 0.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 56 DUF3453 PF11935.8 CRK35412.1 - 1.6e-68 230.8 0.9 2e-67 227.2 0.9 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3453) HMGL-like PF00682.19 CRK35414.1 - 1.8e-73 247.3 0.0 4.3e-73 246.1 0.0 1.6 2 0 0 2 2 2 1 HMGL-like LeuA_dimer PF08502.10 CRK35414.1 - 5.8e-23 81.3 0.0 1.3e-22 80.2 0.0 1.6 1 1 0 1 1 1 1 LeuA allosteric (dimerisation) domain DUF4763 PF15960.5 CRK35416.1 - 0.01 15.2 3.1 0.022 14.0 3.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4763) Fib_alpha PF08702.10 CRK35416.1 - 1.8 8.7 5.3 4.9 7.3 5.3 1.7 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Asp PF00026.23 CRK35418.1 - 3.9e-31 108.6 0.0 2.5e-30 106.0 0.0 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 CRK35418.1 - 0.0015 19.2 0.7 0.15 12.7 0.1 3.0 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 CRK35418.1 - 0.0018 18.8 0.3 0.2 12.2 0.0 2.6 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 CRK35418.1 - 0.0065 16.3 0.3 0.36 10.6 0.1 2.9 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal RVP PF00077.20 CRK35418.1 - 0.15 12.4 0.0 0.72 10.2 0.0 2.0 2 0 0 2 2 2 0 Retroviral aspartyl protease SET PF00856.28 CRK35421.1 - 1.6e-09 38.3 0.0 2.5e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 SET domain zf-MYND PF01753.18 CRK35421.1 - 1.2e-07 31.7 14.2 1.2e-07 31.7 14.2 1.8 2 0 0 2 2 2 1 MYND finger Zn_clus PF00172.18 CRK35423.1 - 4e-07 30.0 10.6 7.2e-07 29.2 10.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RRM_1 PF00076.22 CRK35425.1 - 1.3e-29 101.8 0.2 1.4e-14 53.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HLH PF00010.26 CRK35425.1 - 6.1e-12 45.3 1.2 1.5e-11 44.0 1.2 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain RRM_5 PF13893.6 CRK35425.1 - 4.8e-05 22.9 0.0 0.00093 18.8 0.0 2.3 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CRK35425.1 - 0.0069 16.4 0.3 0.11 12.6 0.1 2.4 2 0 0 2 2 2 1 RNA binding motif GIT_CC PF16559.5 CRK35425.1 - 0.15 12.0 0.4 0.4 10.6 0.4 1.7 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF4776 PF16003.5 CRK35425.1 - 0.2 10.6 2.3 0.36 9.8 2.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) TPR_11 PF13414.6 CRK35427.1 - 1.1e-16 60.2 4.7 1.4e-06 27.9 0.1 3.6 3 0 0 3 3 3 3 TPR repeat TPR_1 PF00515.28 CRK35427.1 - 6.1e-16 57.5 4.2 6.5e-08 32.1 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 CRK35427.1 - 1e-14 53.9 11.2 3e-06 27.6 0.4 4.7 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 CRK35427.1 - 4.5e-14 51.4 13.5 1.3e-06 28.1 0.0 5.3 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 CRK35427.1 - 2.9e-12 46.1 4.9 0.098 13.1 0.0 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 CRK35427.1 - 1.4e-11 44.8 14.7 0.0017 19.0 1.9 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 CRK35427.1 - 1.3e-10 40.7 4.0 1.9e-05 24.5 0.0 4.1 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 CRK35427.1 - 2.6e-07 31.0 13.0 0.013 16.0 0.9 4.2 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 CRK35427.1 - 4.7e-06 26.8 9.1 0.0091 16.3 0.7 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 CRK35427.1 - 5.3e-06 26.7 8.1 0.33 11.7 0.1 5.9 6 1 0 6 6 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 CRK35427.1 - 1.3e-05 24.8 6.7 0.037 14.0 0.1 5.0 4 2 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 CRK35427.1 - 2e-05 24.6 4.1 0.0026 17.9 0.9 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_15 PF13429.6 CRK35427.1 - 0.0066 15.7 4.1 0.0066 15.7 4.1 2.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.6 CRK35427.1 - 0.038 14.3 0.7 0.038 14.3 0.7 3.7 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 CRK35427.1 - 0.061 13.2 0.2 0.061 13.2 0.2 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat BTAD PF03704.17 CRK35427.1 - 0.18 12.2 4.1 3.7 8.0 0.5 2.8 2 0 0 2 2 2 0 Bacterial transcriptional activator domain ANAPC3 PF12895.7 CRK35427.1 - 0.28 11.4 5.3 4 7.7 0.5 2.9 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Ribosomal_S8e PF01201.22 CRK35431.1 - 6.6e-77 256.3 17.8 2.2e-38 131.5 2.5 3.3 3 0 0 3 3 3 2 Ribosomal protein S8e Tim17 PF02466.19 CRK35431.1 - 3e-26 92.0 6.5 2.4e-12 47.2 0.6 2.6 2 0 0 2 2 2 2 Tim17/Tim22/Tim23/Pmp24 family TraB PF01963.17 CRK35431.1 - 0.0007 19.6 5.3 0.34 10.8 0.5 2.2 2 0 0 2 2 2 2 TraB family DUF5518 PF17647.1 CRK35431.1 - 0.031 14.4 13.0 4.2 7.6 0.3 4.2 4 0 0 4 4 4 0 Family of unknown function (DUF5518) Gag_p12 PF01141.18 CRK35431.1 - 0.19 12.1 0.6 32 5.0 0.1 2.5 2 0 0 2 2 2 0 Gag polyprotein, inner coat protein p12 Bud13 PF09736.9 CRK35431.1 - 1.4 9.3 37.3 1.4 9.3 10.5 3.4 3 0 0 3 3 3 0 Pre-mRNA-splicing factor of RES complex MF_alpha_N PF05436.11 CRK35437.1 - 0.22 11.5 0.6 0.7 9.8 0.3 1.9 1 1 1 2 2 2 0 Mating factor alpha precursor N-terminus Methyltransf_PK PF05891.12 CRK35439.1 - 4.5e-65 219.2 0.0 5.2e-65 219.0 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_2 PF00891.18 CRK35439.1 - 0.088 12.1 0.1 0.22 10.8 0.1 1.6 1 1 0 1 1 1 0 O-methyltransferase domain MPC PF03650.13 CRK35439.1 - 0.14 12.4 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial pyruvate carriers Ribosomal_L21p PF00829.21 CRK35441.1 - 3.7e-10 39.9 0.0 4.9e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein CIA30 PF08547.12 CRK35441.1 - 0.23 11.5 0.0 0.31 11.1 0.0 1.2 1 0 0 1 1 1 0 Complex I intermediate-associated protein 30 (CIA30) Pkinase PF00069.25 CRK35443.1 - 2.6e-40 138.5 0.0 4.3e-40 137.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK35443.1 - 9.4e-17 61.1 0.0 1.5e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CRK35443.1 - 1.6 7.4 0.0 1.6 7.4 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase Period_C PF12114.8 CRK35443.1 - 1.7 8.2 11.3 0.022 14.4 2.2 2.2 2 0 0 2 2 2 0 Period protein 2/3C-terminal region Ribosomal_60s PF00428.19 CRK35445.1 - 1.3e-28 99.4 9.9 1.5e-28 99.2 9.9 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein UBA_6 PF18039.1 CRK35445.1 - 0.045 13.7 0.3 0.1 12.5 0.3 1.6 1 0 0 1 1 1 0 UBA-like domain SPT2 PF08243.11 CRK35447.1 - 3.3e-08 34.0 35.1 3.5e-06 27.5 35.1 2.3 1 1 0 1 1 1 1 SPT2 chromatin protein zf_CCCH_4 PF18345.1 CRK35448.1 - 0.006 16.6 6.8 0.0092 16.0 6.8 1.3 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 CRK35448.1 - 0.049 13.6 5.7 0.082 12.8 5.7 1.3 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CRK35448.1 - 0.6 10.0 6.7 4.2 7.3 6.7 2.1 1 1 0 1 1 1 0 CCCH-type zinc finger EMC3_TMCO1 PF01956.16 CRK35449.1 - 3.9e-53 179.7 1.7 5e-53 179.3 1.7 1.1 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like SPC25 PF06703.11 CRK35450.1 - 3e-52 176.7 0.1 3.6e-52 176.4 0.1 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) MMS19_N PF14500.6 CRK35451.1 - 1.8e-52 178.5 0.0 4.6e-52 177.2 0.0 1.7 1 0 0 1 1 1 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.8 CRK35451.1 - 3.7e-11 42.8 0.0 5.3e-09 35.7 0.0 2.9 3 0 0 3 3 3 2 RNAPII transcription regulator C-terminal THF_DHG_CYH PF00763.23 CRK35452.1 - 1.7e-26 92.8 0.2 2.6e-26 92.2 0.2 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 CRK35452.1 - 4.1e-13 48.9 0.0 5.3e-08 32.3 0.0 2.6 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain SBP_bac_5 PF00496.22 CRK35452.1 - 0.0052 15.8 0.0 0.0076 15.3 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle TAP_C PF03943.13 CRK35452.1 - 0.21 11.2 0.2 0.39 10.4 0.2 1.4 1 0 0 1 1 1 0 TAP C-terminal domain LPP PF04728.13 CRK35453.1 - 1.5 9.3 4.0 10 6.6 0.2 2.8 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Apq12 PF12716.7 CRK35454.1 - 1.1e-11 44.4 12.5 2e-11 43.7 12.5 1.4 1 0 0 1 1 1 1 Nuclear pore assembly and biogenesis ATP_bind_1 PF03029.17 CRK35455.1 - 3.1e-50 171.2 0.0 1.4e-43 149.4 0.0 2.0 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 CRK35455.1 - 0.00011 22.1 0.0 0.00055 19.8 0.0 1.9 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_14 PF13173.6 CRK35455.1 - 0.0003 20.8 0.0 0.00094 19.2 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 CRK35455.1 - 0.00041 20.1 0.0 0.00076 19.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 CRK35455.1 - 0.0021 18.1 0.0 0.0024 17.9 0.0 1.2 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain RNA_helicase PF00910.22 CRK35455.1 - 0.0027 18.1 0.0 0.0067 16.8 0.0 1.7 2 0 0 2 2 1 1 RNA helicase AAA_18 PF13238.6 CRK35455.1 - 0.0049 17.4 0.1 0.017 15.7 0.0 2.0 2 1 0 2 2 2 1 AAA domain KAP_NTPase PF07693.14 CRK35455.1 - 0.0078 15.5 0.0 0.012 14.9 0.0 1.3 1 1 0 1 1 1 1 KAP family P-loop domain AAA_33 PF13671.6 CRK35455.1 - 0.0082 16.3 0.0 0.011 15.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain Septin PF00735.18 CRK35455.1 - 0.01 15.1 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 0 Septin MMR_HSR1 PF01926.23 CRK35455.1 - 0.011 15.8 0.0 0.03 14.4 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 CRK35455.1 - 0.012 15.9 0.0 0.027 14.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CRK35455.1 - 0.034 13.7 0.0 0.051 13.1 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 CRK35455.1 - 0.051 14.1 0.0 0.095 13.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 CRK35455.1 - 0.055 13.9 0.0 0.19 12.1 0.0 2.1 1 1 0 1 1 1 0 AAA ATPase domain ATPase_2 PF01637.18 CRK35455.1 - 0.056 13.3 0.0 0.098 12.6 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NACHT PF05729.12 CRK35455.1 - 0.067 13.1 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain FtsK_SpoIIIE PF01580.18 CRK35455.1 - 0.073 12.4 0.0 0.34 10.2 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF87 PF01935.17 CRK35455.1 - 0.074 13.1 0.1 0.49 10.4 0.0 2.2 3 0 0 3 3 3 0 Helicase HerA, central domain Cytidylate_kin PF02224.18 CRK35455.1 - 0.076 12.7 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase SRP54 PF00448.22 CRK35455.1 - 0.079 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_10 PF12846.7 CRK35455.1 - 0.079 11.9 0.0 0.17 10.7 0.0 1.5 2 0 0 2 2 2 0 AAA-like domain AAA_29 PF13555.6 CRK35455.1 - 0.096 12.4 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain PPV_E1_C PF00519.17 CRK35455.1 - 0.11 11.3 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase RsgA_GTPase PF03193.16 CRK35455.1 - 0.14 12.1 0.1 0.29 11.0 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA PF00004.29 CRK35455.1 - 0.15 12.5 0.0 0.28 11.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 CRK35455.1 - 0.15 12.0 0.0 1.1 9.1 0.0 2.0 2 0 0 2 2 2 0 NTPase S-AdoMet_synt_C PF02773.16 CRK35456.1 - 9.4e-67 223.3 0.4 2e-66 222.2 0.0 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 CRK35456.1 - 2.3e-44 150.5 0.0 4.4e-44 149.6 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 CRK35456.1 - 2.9e-44 149.8 0.6 8.7e-44 148.2 0.1 2.0 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain Amidase PF01425.21 CRK35463.1 - 1.3e-81 274.8 0.0 1.8e-81 274.4 0.0 1.2 1 0 0 1 1 1 1 Amidase HMw1_D2 PF18254.1 CRK35463.1 - 0.05 14.0 0.0 3 8.3 0.0 2.3 2 0 0 2 2 2 0 HMW1 domain 2 ARL6IP6 PF15062.6 CRK35463.1 - 0.12 12.5 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 Haemopoietic lineage transmembrane helix Glyco_transf_28 PF03033.20 CRK35465.1 - 1.4e-24 86.7 0.0 3.2e-24 85.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 CRK35465.1 - 8.8e-08 31.4 0.0 1.4e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CRK35465.1 - 0.0039 17.2 0.1 0.0081 16.2 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain VPS13_C PF16909.5 CRK35465.1 - 0.011 15.5 1.7 0.011 15.5 0.2 1.7 2 0 0 2 2 2 0 Vacuolar-sorting-associated 13 protein C-terminal ATG_C PF09333.11 CRK35465.1 - 0.099 13.0 0.2 0.76 10.2 0.0 2.4 2 0 0 2 2 2 0 Autophagy-related protein C terminal domain Fungal_trans_2 PF11951.8 CRK35468.1 - 8.3e-05 21.6 0.6 0.00013 20.9 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK35468.1 - 0.00018 21.6 1.4 0.00018 21.6 1.4 2.4 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PALP PF00291.25 CRK35474.1 - 4.7e-19 68.9 0.2 5.3e-19 68.7 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme KAR9 PF08580.10 CRK35475.1 - 0.11 11.0 0.3 0.45 9.0 0.1 1.8 2 0 0 2 2 2 0 Yeast cortical protein KAR9 CDP-OH_P_transf PF01066.21 CRK35476.1 - 2.9e-12 47.2 0.8 2.9e-12 47.2 0.8 2.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Thermopsin PF05317.11 CRK35476.1 - 0.039 13.4 0.1 0.064 12.7 0.1 1.3 1 0 0 1 1 1 0 Thermopsin Transket_pyr PF02779.24 CRK35477.1 - 1.4e-17 63.9 0.0 1.8e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain UPF0228 PF05727.11 CRK35477.1 - 0.17 11.7 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0228) ATP-synt_C PF00137.21 CRK35478.1 - 1.1e-10 41.7 8.1 8.2e-06 26.1 0.4 2.1 2 0 0 2 2 2 2 ATP synthase subunit C SLATT_5 PF18160.1 CRK35478.1 - 0.051 12.9 0.1 0.051 12.9 0.1 1.1 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 COX7a PF02238.15 CRK35478.1 - 2.8 8.4 5.0 0.74 10.3 1.7 1.7 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VII GDC-P PF02347.16 CRK35479.1 - 4.1e-39 134.6 0.1 4.2e-39 134.6 0.1 1.0 1 0 0 1 1 1 1 Glycine cleavage system P-protein HpaB PF03241.13 CRK35480.1 - 0.071 12.2 0.0 0.088 11.9 0.0 1.2 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase C terminal Mso1_Sec1_bdg PF14475.6 CRK35481.1 - 8.4e-21 73.3 0.1 1.2e-20 72.8 0.1 1.2 1 0 0 1 1 1 1 Sec1-binding region of Mso1 DIT1_PvcA PF05141.12 CRK35483.1 - 1.5e-89 300.1 0.0 1.9e-89 299.8 0.0 1.1 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein TauD PF02668.16 CRK35483.1 - 5.5e-26 91.9 0.2 3.1e-25 89.5 0.1 2.2 2 1 0 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family DEAD PF00270.29 CRK35484.1 - 2.9e-43 147.7 0.0 4.9e-43 146.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CRK35484.1 - 7.9e-28 97.0 0.6 7.2e-27 93.9 0.3 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.6 CRK35484.1 - 0.17 11.2 0.0 0.37 10.1 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit API5 PF05918.11 CRK35484.1 - 0.27 10.0 11.9 0.46 9.2 11.9 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) GRP PF07172.11 CRK35484.1 - 2.3 9.0 20.4 4.9 7.9 20.4 1.5 1 0 0 1 1 1 0 Glycine rich protein family Chitin_synth_1 PF01644.17 CRK35485.1 - 1.1e-58 197.8 0.0 1.6e-58 197.3 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 CRK35485.1 - 1e-27 97.0 0.1 1.8e-22 79.7 0.0 2.1 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 CRK35485.1 - 4.9e-09 36.4 0.1 4.9e-09 36.4 0.1 2.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 CRK35485.1 - 0.03 14.2 0.0 0.05 13.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Peptidase_S8 PF00082.22 CRK35486.1 - 5.5e-10 39.0 0.9 5.9e-10 38.9 0.9 1.1 1 0 0 1 1 1 1 Subtilase family ATG22 PF11700.8 CRK35488.1 - 2.2e-87 293.7 6.2 2.5e-87 293.5 6.2 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 CRK35488.1 - 2.3e-09 36.6 10.7 2.7e-09 36.4 10.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily FPN1 PF06963.12 CRK35488.1 - 0.012 14.3 0.5 0.38 9.3 0.3 2.2 2 0 0 2 2 2 0 Ferroportin1 (FPN1) MFS_2 PF13347.6 CRK35488.1 - 0.013 14.1 7.5 0.017 13.7 7.5 1.2 1 0 0 1 1 1 0 MFS/sugar transport protein CLN3 PF02487.17 CRK35488.1 - 0.029 13.4 0.3 0.045 12.8 0.3 1.3 1 0 0 1 1 1 0 CLN3 protein Transgly_assoc PF04226.13 CRK35488.1 - 0.63 10.3 5.5 5.2 7.4 0.7 2.9 2 0 0 2 2 2 0 Transglycosylase associated protein Peptidase_M24 PF00557.24 CRK35490.1 - 1.2e-38 132.9 0.2 1.6e-38 132.5 0.2 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 TruD PF01142.18 CRK35492.1 - 2.4e-17 62.9 0.0 2.6e-17 62.8 0.0 1.0 1 0 0 1 1 1 1 tRNA pseudouridine synthase D (TruD) Rif1_N PF12231.8 CRK35493.1 - 3.3e-31 108.6 1.0 3.5e-31 108.5 1.0 1.0 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal MIP PF00230.20 CRK35494.1 - 7.5e-49 166.5 14.5 9.8e-49 166.1 14.5 1.1 1 0 0 1 1 1 1 Major intrinsic protein COX4 PF02936.14 CRK35494.1 - 0.19 11.7 0.6 0.67 10.0 0.1 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase subunit IV HPP PF04982.13 CRK35495.1 - 4.5e-39 133.4 9.7 4.5e-39 133.4 9.7 1.6 2 0 0 2 2 2 1 HPP family Glyco_hydro_1 PF00232.18 CRK35496.1 - 3.8e-36 124.5 0.0 3.3e-31 108.2 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 1 C2 PF00168.30 CRK35498.1 - 0.013 15.7 0.0 0.016 15.5 0.0 1.0 1 0 0 1 1 1 0 C2 domain Glyco_hydro_76 PF03663.14 CRK35500.1 - 9e-28 97.8 0.0 9.3e-28 97.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 RNase_PH PF01138.21 CRK35501.1 - 0.1 13.1 0.0 0.18 12.3 0.0 1.5 1 1 0 1 1 1 0 3' exoribonuclease family, domain 1 Polysacc_deac_1 PF01522.21 CRK35502.1 - 4.3e-15 55.7 0.0 5.1e-15 55.5 0.0 1.0 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 CRK35502.1 - 0.00067 19.0 0.0 0.00077 18.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 NIF PF03031.18 CRK35503.1 - 2.3e-23 82.7 0.0 3.8e-23 82.0 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Sec61_beta PF03911.16 CRK35503.1 - 5.1e-17 61.6 0.9 9e-17 60.8 0.9 1.4 1 0 0 1 1 1 1 Sec61beta family UIM PF02809.20 CRK35503.1 - 3e-07 29.9 27.8 0.29 11.2 0.2 7.2 6 0 0 6 6 6 5 Ubiquitin interaction motif ATG_C PF09333.11 CRK35503.1 - 2.2e-05 24.7 0.0 7.1e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain Peptidase_A22B PF04258.13 CRK35505.1 - 2.3e-13 50.3 0.0 2.7e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 Signal peptide peptidase PRELI PF04707.14 CRK35506.1 - 4.2e-22 78.6 0.3 4.9e-22 78.4 0.3 1.0 1 0 0 1 1 1 1 PRELI-like family Acyl-CoA_dh_M PF02770.19 CRK35507.1 - 1.3e-11 44.5 0.0 1.9e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 CRK35507.1 - 0.04 14.1 0.1 0.05 13.8 0.1 1.2 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain Peptidase_M16 PF00675.20 CRK35510.1 - 5.3e-06 26.5 0.1 6.7e-06 26.2 0.1 1.2 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) NOPS PF08075.11 CRK35510.1 - 0.15 12.3 0.8 0.38 11.0 0.8 1.7 1 0 0 1 1 1 0 NOPS (NUC059) domain Adaptin_N PF01602.20 CRK35514.1 - 1.1e-94 317.9 7.4 1.4e-94 317.6 7.4 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CRK35514.1 - 3.6e-15 56.4 3.4 4.9e-11 42.9 0.0 2.9 1 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CRK35514.1 - 9.8e-11 41.9 1.3 0.0013 19.0 0.0 4.9 1 1 3 4 4 4 4 HEAT repeats HEAT PF02985.22 CRK35514.1 - 2.5e-05 24.1 1.3 1.1 9.8 0.0 4.9 5 0 0 5 5 5 2 HEAT repeat DUF5578 PF17741.1 CRK35514.1 - 0.0013 18.2 2.6 0.32 10.4 0.4 2.8 2 1 1 3 3 3 2 Family of unknown function (DUF5578) DUF5071 PF16804.5 CRK35514.1 - 0.024 14.9 3.3 4.8 7.5 0.0 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF5071) HEAT_EZ PF13513.6 CRK35514.1 - 0.13 12.8 1.2 16 6.1 0.0 4.1 5 0 0 5 5 5 0 HEAT-like repeat Meis_PKNOX_N PF16493.5 CRK35514.1 - 0.23 11.8 1.2 0.58 10.5 1.2 1.7 1 0 0 1 1 1 0 N-terminal of Homeobox Meis and PKNOX1 Ras PF00071.22 CRK35515.1 - 0.12 12.0 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Ras family STI1 PF17830.1 CRK35516.1 - 5.3e-18 64.7 3.8 6.6e-18 64.4 3.8 1.2 1 0 0 1 1 1 1 STI1 domain RHH_7 PF16777.5 CRK35527.1 - 0.016 15.6 0.0 0.022 15.2 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator, RHH-like, CopG LIM_bind PF01803.16 CRK35529.1 - 6.2e-27 94.7 0.0 6.8e-27 94.6 0.0 1.0 1 0 0 1 1 1 1 LIM-domain binding protein Peptidase_C50 PF03568.17 CRK35532.1 - 2.9e-22 79.3 0.0 3e-22 79.3 0.0 1.0 1 0 0 1 1 1 1 Peptidase family C50 Tctex-1 PF03645.13 CRK35537.1 - 5.2e-19 68.4 0.0 5.9e-19 68.2 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family Lactonase PF10282.9 CRK35539.1 - 4.8e-16 59.0 0.0 5.2e-16 58.8 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller HGTP_anticodon2 PF12745.7 CRK35540.1 - 1.8e-74 250.6 9.3 3.4e-74 249.7 9.3 1.4 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs UQ_con PF00179.26 CRK35540.1 - 2e-32 111.8 0.1 4.2e-32 110.7 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme IGPD PF00475.18 CRK35540.1 - 2.2e-08 34.5 0.1 4.4e-08 33.5 0.1 1.5 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase Pkinase PF00069.25 CRK35540.1 - 1.3e-07 31.3 0.0 5.4e-07 29.2 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK35540.1 - 0.00064 19.1 0.0 0.0013 18.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HMG-CoA_red PF00368.18 CRK35540.1 - 0.096 11.7 0.6 0.14 11.1 0.6 1.2 1 0 0 1 1 1 0 Hydroxymethylglutaryl-coenzyme A reductase APH PF01636.23 CRK35540.1 - 0.23 11.3 3.0 0.13 12.2 0.8 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Rubis-subs-bind PF09273.11 CRK35541.1 - 0.00021 22.0 0.3 0.00025 21.7 0.3 1.2 1 1 0 1 1 1 1 Rubisco LSMT substrate-binding Frataxin_Cyay PF01491.16 CRK35542.1 - 1.9e-21 76.1 0.0 2.2e-21 76.0 0.0 1.0 1 0 0 1 1 1 1 Frataxin-like domain INO80_Ies4 PF08193.11 CRK35543.1 - 0.0034 17.4 2.7 0.0039 17.2 2.7 1.0 1 0 0 1 1 1 1 INO80 complex subunit Ies4 His_Phos_1 PF00300.22 CRK35545.1 - 3e-07 30.3 0.1 3.3e-07 30.2 0.1 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) ketoacyl-synt PF00109.26 CRK35548.1 - 3e-77 259.6 0.0 6.1e-77 258.6 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 CRK35548.1 - 3.7e-60 202.9 1.7 1.3e-59 201.1 1.7 2.1 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 CRK35548.1 - 1.6e-53 182.3 0.1 2.8e-53 181.5 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 CRK35548.1 - 7.6e-51 173.1 0.1 1.3e-50 172.3 0.1 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 CRK35548.1 - 3.2e-41 140.1 0.0 1.2e-40 138.2 0.0 2.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 CRK35548.1 - 6.1e-19 68.5 0.0 8.3e-18 64.9 0.0 2.6 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 CRK35548.1 - 9.2e-17 61.1 2.3 2.7e-14 53.1 0.3 2.7 2 0 0 2 2 2 2 short chain dehydrogenase ADH_zinc_N_2 PF13602.6 CRK35548.1 - 1.7e-13 51.8 0.0 1e-12 49.2 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short_C2 PF13561.6 CRK35548.1 - 3.9e-11 43.0 3.3 2.6e-10 40.3 0.4 2.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase ADH_zinc_N PF00107.26 CRK35548.1 - 4.9e-09 36.2 0.1 1.4e-08 34.7 0.1 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CRK35548.1 - 1.9e-05 24.5 0.0 5.7e-05 23.0 0.0 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.23 CRK35548.1 - 4.4e-05 23.0 0.2 9.4e-05 21.9 0.2 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Sacchrp_dh_NADP PF03435.18 CRK35548.1 - 0.0049 17.1 0.0 1.5 9.1 0.0 3.1 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 CRK35548.1 - 0.034 13.3 0.0 0.067 12.3 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ACP_syn_III PF08545.10 CRK35548.1 - 0.072 12.9 0.0 0.28 11.0 0.0 2.2 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ABC_membrane PF00664.23 CRK35549.1 - 3.1e-75 253.3 45.3 5.9e-41 140.9 16.7 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region FSH1 PF03959.13 CRK35549.1 - 4.1e-30 105.0 0.0 1.1e-29 103.6 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) RF-1 PF00472.20 CRK35549.1 - 2.1e-15 56.7 7.8 1.4e-12 47.6 6.2 2.4 2 0 0 2 2 2 2 RF-1 domain ABC_tran PF00005.27 CRK35549.1 - 3.4e-13 50.3 0.0 1.5e-12 48.2 0.0 2.0 1 1 1 2 2 2 1 ABC transporter AAA_29 PF13555.6 CRK35549.1 - 0.00014 21.5 0.3 0.0031 17.2 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.6 CRK35549.1 - 0.021 15.3 0.1 0.021 15.3 0.1 1.7 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 CRK35549.1 - 0.074 13.0 0.0 0.2 11.5 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 CRK35549.1 - 0.12 12.6 0.0 0.38 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 CRK35549.1 - 0.14 11.7 0.0 0.33 10.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 CRK35549.1 - 0.17 11.7 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Actin PF00022.19 CRK35550.1 - 3.8e-150 500.0 0.0 1.5e-149 498.1 0.0 1.7 1 1 0 1 1 1 1 Actin Ribosomal_L5_C PF00673.21 CRK35551.1 - 1.1e-25 89.6 0.0 1.9e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 CRK35551.1 - 6.1e-05 23.3 0.1 0.00011 22.5 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L5 UCH_1 PF13423.6 CRK35552.1 - 1.1e-36 127.1 0.0 3e-36 125.7 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.29 CRK35552.1 - 4.7e-15 55.8 0.0 1.4e-14 54.2 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase YafQ_toxin PF15738.5 CRK35552.1 - 0.13 12.6 0.7 39 4.7 0.0 3.0 3 0 0 3 3 3 0 Bacterial toxin of type II toxin-antitoxin system, YafQ Telomere_Sde2_2 PF13297.6 CRK35552.1 - 7.6 6.3 7.5 10 5.9 0.2 2.7 3 0 0 3 3 3 0 Telomere stability C-terminal 6PF2K PF01591.18 CRK35553.1 - 1.6e-23 83.2 2.7 2e-23 82.9 1.4 1.8 2 0 0 2 2 2 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 CRK35553.1 - 7.8e-19 68.1 0.2 5.3e-18 65.4 0.2 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Transglut_core PF01841.19 CRK35553.1 - 2.6e-11 43.9 0.6 6.3e-11 42.7 0.6 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily SH3_2 PF07653.17 CRK35553.1 - 1.6e-08 34.1 0.1 6.7e-08 32.1 0.2 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 CRK35553.1 - 0.00012 21.6 0.2 0.00012 21.6 0.2 2.5 3 0 0 3 3 3 1 SH3 domain SH3_9 PF14604.6 CRK35553.1 - 0.0021 17.8 0.4 0.014 15.3 0.3 2.3 2 0 0 2 2 2 1 Variant SH3 domain SARAF PF06682.12 CRK35553.1 - 0.0077 15.9 4.4 0.014 15.0 4.4 1.4 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis Porin_3 PF01459.22 CRK35554.1 - 3.8e-31 108.6 0.1 4.2e-31 108.4 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic porin Pkinase PF00069.25 CRK35555.1 - 4.4e-70 236.1 0.0 6.4e-70 235.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK35555.1 - 6.6e-49 166.5 0.0 9.7e-49 166.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CRK35555.1 - 9.6e-06 25.1 0.0 0.00014 21.3 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CRK35555.1 - 3.2e-05 22.9 0.1 7.3e-05 21.7 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Porin_3 PF01459.22 CRK35557.1 - 9.1e-57 192.6 1.4 7.6e-32 110.8 0.1 2.0 2 0 0 2 2 2 2 Eukaryotic porin DUF410 PF04190.13 CRK35558.1 - 1.2e-92 310.4 0.0 1.5e-92 310.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) Pkinase PF00069.25 CRK35560.1 - 4e-70 236.2 0.0 5.9e-70 235.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK35560.1 - 6.1e-49 166.6 0.0 9e-49 166.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CRK35560.1 - 8.7e-06 25.3 0.0 0.00014 21.3 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CRK35560.1 - 2.7e-05 23.1 0.1 7e-05 21.8 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase RAI1 PF08652.11 CRK35561.1 - 0.025 14.8 0.6 0.11 12.7 0.0 2.3 3 0 0 3 3 3 0 RAI1 like PD-(D/E)XK nuclease CsoSCA PF08936.10 CRK35561.1 - 0.16 10.6 0.4 12 4.5 0.1 2.0 2 0 0 2 2 2 0 Carboxysome Shell Carbonic Anhydrase Sec8_exocyst PF04048.14 CRK35562.1 - 2.6e-48 163.5 0.5 7.4e-48 162.1 0.5 1.8 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 CRK35562.1 - 7.6e-10 38.5 0.5 1.6e-09 37.5 0.5 1.5 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex WD40 PF00400.32 CRK35563.1 - 6.2e-27 93.3 15.0 2.3e-06 28.2 0.1 9.4 9 0 0 9 9 9 6 WD domain, G-beta repeat NLE PF08154.12 CRK35563.1 - 2.3e-16 60.0 0.5 4.1e-16 59.2 0.5 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.8 CRK35563.1 - 1.6e-07 30.3 5.8 0.035 12.7 0.0 4.0 3 1 0 4 4 4 3 Nucleoporin Nup120/160 DUF1989 PF09347.10 CRK35563.1 - 0.0014 18.3 0.2 1.4 8.6 0.1 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF1989) KTI12 PF08433.10 CRK35563.1 - 0.14 11.6 0.1 17 4.7 0.0 2.2 2 0 0 2 2 2 0 Chromatin associated protein KTI12 MIF4G_like PF09088.11 CRK35564.1 - 3.1e-164 542.4 9.2 7.5e-88 293.3 0.4 3.4 3 0 0 3 3 3 3 MIF4G like MIF4G_like_2 PF09090.11 CRK35564.1 - 3.6e-141 469.3 2.9 8.6e-70 235.2 0.2 2.3 2 0 0 2 2 2 2 MIF4G like Pkinase PF00069.25 CRK35564.1 - 1e-115 385.6 0.0 4.4e-63 213.1 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CRK35564.1 - 2.7e-40 138.3 0.0 2.3e-23 82.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CRK35564.1 - 4.7e-12 45.8 0.0 0.00011 21.6 0.0 2.4 2 0 0 2 2 2 2 Kinase-like NLE PF08154.12 CRK35564.1 - 1.2e-07 32.1 0.7 1.4e-05 25.5 0.7 2.9 1 1 0 1 1 1 1 NLE (NUC135) domain APH PF01636.23 CRK35564.1 - 4e-07 30.2 0.1 0.058 13.3 0.1 3.7 2 1 0 2 2 2 2 Phosphotransferase enzyme family DUF1229 PF06797.11 CRK35564.1 - 0.00019 21.7 2.0 0.52 10.5 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1229) Kdo PF06293.14 CRK35564.1 - 0.00055 19.3 0.0 1.4 8.2 0.0 2.6 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 CRK35564.1 - 0.0012 18.5 0.0 1.4 8.5 0.0 2.4 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Orthopox_A5L PF06193.11 CRK35564.1 - 0.0013 18.3 0.1 2.3 7.6 0.0 2.6 3 0 0 3 3 3 2 Orthopoxvirus A5L protein-like HTH_32 PF13565.6 CRK35564.1 - 0.0025 18.4 14.1 0.35 11.5 2.8 3.2 2 0 0 2 2 2 2 Homeodomain-like domain Choline_kinase PF01633.20 CRK35564.1 - 0.0058 16.2 0.0 4.7 6.7 0.0 2.4 2 0 0 2 2 2 2 Choline/ethanolamine kinase WD40 PF00400.32 CRK35564.1 - 0.0064 17.3 1.3 0.94 10.5 0.6 3.5 2 0 0 2 2 2 1 WD domain, G-beta repeat Grg1 PF11034.8 CRK35564.1 - 0.058 13.6 3.5 7.4 6.9 0.3 2.7 2 0 0 2 2 2 0 Glucose-repressible protein Grg1 MIF4G PF02854.19 CRK35564.1 - 1.5 8.4 4.0 24 4.5 0.0 3.0 4 0 0 4 4 3 0 MIF4G domain K_channel_TID PF07941.11 CRK35564.1 - 8.4 6.9 8.1 37 4.9 0.9 2.9 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Plasmid_RAQPRD PF09686.10 CRK35565.1 - 0.14 12.4 0.0 28 5.0 0.0 2.3 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Pribosyl_synth PF14572.6 CRK35566.1 - 4.3e-38 131.2 0.7 4.7e-38 131.0 0.7 1.0 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 CRK35566.1 - 1.9e-06 27.5 0.4 2.8e-06 26.9 0.4 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CRK35566.1 - 0.00072 19.1 0.4 0.00096 18.6 0.4 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase UPF0181 PF03701.14 CRK35566.1 - 0.12 12.0 0.2 3.6 7.3 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0181) Chlorosome_CsmC PF11098.8 CRK35566.1 - 0.24 11.4 2.7 0.36 10.8 1.8 1.8 1 1 1 2 2 2 0 Chlorosome envelope protein C UPF0220 PF05255.11 CRK35567.1 - 1.7e-66 222.9 4.8 2.1e-66 222.6 4.8 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DUF3169 PF11368.8 CRK35567.1 - 0.081 12.4 1.2 0.12 11.9 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) DUF5337 PF17272.2 CRK35567.1 - 0.46 10.4 4.3 0.71 9.8 0.4 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5337) DNA_pol_A_exo1 PF01612.20 CRK35568.1 - 4.5e-12 46.0 0.0 8e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 3'-5' exonuclease LSM PF01423.22 CRK35569.1 - 2.1e-22 78.6 0.1 2.3e-22 78.4 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CRK35569.1 - 0.023 14.8 0.0 0.026 14.7 0.0 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain BPL_C PF02237.17 CRK35569.1 - 0.042 13.7 0.0 2.3 8.2 0.0 2.2 2 0 0 2 2 2 0 Biotin protein ligase C terminal domain LSM14 PF12701.7 CRK35569.1 - 0.11 12.6 0.0 0.14 12.3 0.0 1.3 1 1 0 1 1 1 0 Scd6-like Sm domain RNA_pol_L_2 PF13656.6 CRK35570.1 - 2.8e-24 84.7 0.3 3.5e-24 84.4 0.3 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 CRK35570.1 - 1.2e-07 31.1 0.0 1.2e-06 27.9 0.0 2.1 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Cep57_MT_bd PF06657.13 CRK35570.1 - 0.055 13.9 0.3 0.28 11.7 0.0 2.1 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DNA_pol_A_exo1 PF01612.20 CRK35571.1 - 1.8e-12 47.3 0.0 3e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 3'-5' exonuclease LSM PF01423.22 CRK35572.1 - 2.1e-22 78.6 0.1 2.3e-22 78.4 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CRK35572.1 - 0.023 14.8 0.0 0.026 14.7 0.0 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain BPL_C PF02237.17 CRK35572.1 - 0.042 13.7 0.0 2.3 8.2 0.0 2.2 2 0 0 2 2 2 0 Biotin protein ligase C terminal domain LSM14 PF12701.7 CRK35572.1 - 0.11 12.6 0.0 0.14 12.3 0.0 1.3 1 1 0 1 1 1 0 Scd6-like Sm domain RNA_pol_L_2 PF13656.6 CRK35573.1 - 2.8e-24 84.7 0.3 3.5e-24 84.4 0.3 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 CRK35573.1 - 1.2e-07 31.1 0.0 1.2e-06 27.9 0.0 2.1 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Cep57_MT_bd PF06657.13 CRK35573.1 - 0.055 13.9 0.3 0.28 11.7 0.0 2.1 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Aa_trans PF01490.18 CRK35574.1 - 1.1e-128 429.5 67.8 1.1e-79 268.1 36.3 2.1 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein SP_C-Propep PF08999.10 CRK35574.1 - 0.027 14.3 0.4 3.2 7.6 0.1 2.4 2 0 0 2 2 2 0 Surfactant protein C, N terminal propeptide Pep1_7 PF17232.2 CRK35574.1 - 0.68 10.4 3.1 31 5.1 0.2 2.7 2 0 0 2 2 2 0 Elicitor peptide 1-7 SurA_N_3 PF13624.6 CRK35574.1 - 0.99 9.2 2.6 25 4.6 0.2 2.5 2 0 0 2 2 2 0 SurA N-terminal domain FixH PF05751.11 CRK35574.1 - 1.6 8.7 10.7 4 7.4 2.4 2.7 2 0 0 2 2 2 0 FixH AA_permease PF00324.21 CRK35575.1 - 4.8e-35 121.1 15.2 5.5e-35 120.9 15.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CRK35575.1 - 2.9e-08 33.0 15.2 3.6e-08 32.7 15.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CRK35576.1 - 2.3e-61 207.9 31.4 2.9e-61 207.5 31.4 1.1 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 CRK35576.1 - 6.4e-24 84.8 0.2 7.2e-10 38.5 0.0 3.2 3 0 0 3 3 3 3 Solute carrier family 12 WD40 PF00400.32 CRK35576.1 - 5.3e-17 61.9 0.1 0.0056 17.5 0.1 6.2 5 0 0 5 5 5 3 WD domain, G-beta repeat AA_permease_2 PF13520.6 CRK35576.1 - 9.4e-17 60.9 37.1 1.4e-16 60.3 37.1 1.2 1 0 0 1 1 1 1 Amino acid permease ANAPC4_WD40 PF12894.7 CRK35576.1 - 8.2e-05 22.8 0.9 3.4 8.0 0.0 5.9 3 1 3 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain MTS PF05175.14 CRK35576.1 - 0.00028 20.5 0.0 0.0011 18.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain PrmC_N PF17827.1 CRK35576.1 - 0.0064 17.1 0.1 0.026 15.1 0.1 2.1 1 0 0 1 1 1 1 PrmC N-terminal domain PrmA PF06325.13 CRK35576.1 - 0.024 14.1 0.3 0.086 12.2 0.0 2.0 3 0 0 3 3 3 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 CRK35576.1 - 0.056 14.1 0.0 0.15 12.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 CRK35576.1 - 0.066 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Blt1_C PF17183.4 CRK35576.1 - 0.18 11.5 0.8 0.46 10.1 0.8 1.6 1 0 0 1 1 1 0 Get5 carboxyl domain Glyco_transf_15 PF01793.16 CRK35577.1 - 3.2e-114 381.5 5.4 3.9e-114 381.3 5.4 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase GCP_N_terminal PF17681.1 CRK35578.1 - 3e-39 135.5 0.0 4.2e-39 135.0 0.0 1.2 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP5-Mod21 PF14609.6 CRK35578.1 - 0.0025 16.2 0.0 0.0041 15.5 0.0 1.3 1 0 0 1 1 1 1 gamma-Tubulin ring complex non-core subunit mod21 GCP_N_terminal PF17681.1 CRK35579.1 - 2.1e-38 132.7 0.0 3.1e-38 132.1 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 CRK35579.1 - 1.2e-22 80.8 0.0 1.7e-22 80.3 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal DUF572 PF04502.13 CRK35580.1 - 8.7e-23 81.5 3.9 1.4e-22 80.8 1.8 1.9 2 0 0 2 2 2 1 Family of unknown function (DUF572) GCP_C_terminal PF04130.13 CRK35580.1 - 6.4e-20 71.8 0.0 7.7e-20 71.6 0.0 1.1 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal DUF572 PF04502.13 CRK35581.1 - 1.2e-76 258.5 14.9 4.2e-65 220.6 0.8 2.0 2 0 0 2 2 2 2 Family of unknown function (DUF572) WYL_3 PF18488.1 CRK35581.1 - 0.0064 16.8 0.1 5.7 7.4 0.0 2.5 2 0 0 2 2 2 2 WYL domain NTS PF15447.6 CRK35581.1 - 0.0093 16.4 0.0 8.9 6.9 0.0 2.8 2 0 0 2 2 2 2 N-terminal segments of PfEMP1 Yqai PF09466.10 CRK35581.1 - 0.1 12.9 0.9 24 5.3 0.1 2.6 2 0 0 2 2 2 0 Hypothetical protein Yqai DUF3446 PF11928.8 CRK35581.1 - 0.4 11.0 23.1 2.2 8.6 5.5 2.6 2 0 0 2 2 2 0 Early growth response N-terminal domain DUF1690 PF07956.11 CRK35581.1 - 0.57 10.6 19.0 3.6 8.0 5.0 2.6 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) NeA_P2 PF12312.8 CRK35581.1 - 1.1 8.7 6.6 3.4 7.0 0.9 2.7 2 0 0 2 2 2 0 Nepovirus subgroup A polyprotein SR-25 PF10500.9 CRK35581.1 - 5.5 6.5 34.7 1.3 8.6 13.5 2.9 1 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein PBP PF01161.20 CRK35584.1 - 2.1e-13 50.7 0.2 3.6e-13 50.0 0.2 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Pyr_redox_2 PF07992.14 CRK35585.1 - 8.1e-29 100.8 1.6 1e-28 100.4 1.6 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CRK35585.1 - 5.5e-09 36.5 4.2 1.1e-08 35.5 1.7 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CRK35585.1 - 0.00061 19.8 5.6 0.39 10.7 0.0 3.4 4 0 0 4 4 4 2 FAD-NAD(P)-binding K_oxygenase PF13434.6 CRK35585.1 - 0.0085 15.3 0.2 0.1 11.7 0.2 2.3 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) TrkA_N PF02254.18 CRK35585.1 - 0.19 12.0 2.2 7.7 6.8 0.0 3.2 2 2 0 2 2 2 0 TrkA-N domain Malic_M PF03949.15 CRK35585.1 - 0.44 9.8 0.1 0.44 9.8 0.1 2.7 3 0 0 3 3 3 0 Malic enzyme, NAD binding domain DAO PF01266.24 CRK35585.1 - 0.54 9.8 15.7 0.44 10.1 0.2 3.8 2 2 1 4 4 4 0 FAD dependent oxidoreductase tRNA-synt_1 PF00133.22 CRK35588.1 - 1e-45 156.1 4.3 5.3e-19 67.9 0.1 6.1 2 1 3 5 5 5 5 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 CRK35588.1 - 1.6e-41 141.8 0.0 2.7e-41 141.1 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 CRK35588.1 - 9.1e-28 97.1 0.0 3.5e-19 68.8 0.0 4.1 3 1 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 CRK35588.1 - 8.2e-13 48.6 0.0 1.5e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA MTHFR PF02219.17 CRK35589.1 - 2.8e-99 332.1 0.0 3.9e-99 331.6 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase AIRS_C PF02769.22 CRK35592.1 - 4.3e-25 88.7 1.4 6.1e-24 84.9 0.0 2.8 3 0 0 3 3 3 1 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 CRK35592.1 - 6.5e-22 77.7 0.0 1.3e-21 76.7 0.0 1.5 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 CRK35592.1 - 2.2e-21 76.1 0.0 4.2e-21 75.2 0.0 1.5 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain PQ-loop PF04193.14 CRK35593.1 - 8.4e-05 22.3 0.1 0.00013 21.6 0.1 1.4 1 1 0 1 1 1 1 PQ loop repeat GATase_5 PF13507.6 CRK35594.1 - 1.2e-94 316.2 0.0 1.8e-94 315.7 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 CRK35594.1 - 1.7e-36 125.7 0.6 9.9e-24 84.2 0.0 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 CRK35594.1 - 2e-24 85.8 0.0 3.4e-24 85.0 0.0 1.4 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 CRK35594.1 - 1.7e-21 76.5 0.0 3.5e-21 75.5 0.0 1.6 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain GATase_5 PF13507.6 CRK35595.1 - 2.6e-81 272.5 0.0 1e-80 270.6 0.0 1.9 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 CRK35595.1 - 8.3e-11 42.3 0.1 1.7e-10 41.3 0.1 1.5 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain Suc_Fer-like PF06999.12 CRK35596.1 - 7.7e-71 238.0 0.0 2.8e-57 193.8 0.0 2.1 2 0 0 2 2 2 2 Sucrase/ferredoxin-like Zn_clus PF00172.18 CRK35596.1 - 1.1e-07 31.9 8.4 1.8e-07 31.2 8.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_6 PF00970.24 CRK35597.1 - 6.7e-10 39.2 0.0 1.4e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 CRK35597.1 - 0.0066 17.1 0.0 0.012 16.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 CRK35597.1 - 0.057 13.5 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Ferric reductase NAD binding domain PhoLip_ATPase_C PF16212.5 CRK35599.1 - 3.3e-51 174.4 5.6 4.3e-51 174.1 5.6 1.1 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal Hydrolase PF00702.26 CRK35599.1 - 7e-10 39.5 0.0 0.0003 21.2 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CRK35599.1 - 0.0011 18.8 0.0 0.0017 18.1 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Suc_Fer-like PF06999.12 CRK35600.1 - 1.4e-41 142.5 0.0 1.7e-41 142.3 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like FAD_binding_6 PF00970.24 CRK35601.1 - 1.1e-09 38.5 0.0 2.3e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 CRK35601.1 - 0.0033 18.1 0.0 0.006 17.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 CRK35601.1 - 0.18 12.0 0.0 0.33 11.1 0.0 1.4 1 0 0 1 1 1 0 Ferric reductase NAD binding domain PhoLip_ATPase_C PF16212.5 CRK35602.1 - 1.9e-50 172.0 6.0 1.9e-50 172.0 6.0 1.9 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CRK35602.1 - 7.2e-16 57.6 0.3 1.6e-15 56.5 0.3 1.6 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 CRK35602.1 - 1.7e-12 48.1 0.0 7e-07 29.8 0.1 2.8 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 CRK35602.1 - 1.2e-07 31.4 4.3 0.00039 20.0 0.1 3.0 3 0 0 3 3 3 2 E1-E2 ATPase Hydrolase_3 PF08282.12 CRK35602.1 - 0.0025 17.6 0.0 0.0052 16.6 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HIGH_NTase1_ass PF16581.5 CRK35602.1 - 0.042 13.9 0.0 0.099 12.6 0.0 1.5 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region DEADboxA PF12343.8 CRK35602.1 - 0.32 11.5 14.4 1.1 9.8 14.4 2.0 1 0 0 1 1 1 0 Cold shock protein DEAD box A DUF3684 PF12449.8 CRK35603.1 - 5.5e-133 445.0 2.9 7.5e-133 444.6 2.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) Sec16_C PF12931.7 CRK35603.1 - 1.6e-115 385.9 0.1 2.6e-115 385.2 0.1 1.3 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 CRK35603.1 - 3.3e-32 111.5 0.0 9.9e-32 110.0 0.0 1.9 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region HATPase_c_3 PF13589.6 CRK35603.1 - 2.8e-06 27.2 1.2 0.0004 20.2 0.0 3.7 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Nup96 PF12110.8 CRK35603.1 - 0.0087 15.2 0.0 0.025 13.7 0.0 1.7 2 0 0 2 2 2 1 Nuclear protein 96 HATPase_c_3 PF13589.6 CRK35604.1 - 0.00025 20.9 0.0 0.00037 20.3 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF664 PF04978.12 CRK35604.1 - 0.013 16.0 0.3 0.014 15.9 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF664) PhoLip_ATPase_N PF16209.5 CRK35605.1 - 5.7e-16 58.0 0.3 1.1e-15 57.0 0.3 1.5 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 CRK35605.1 - 1.1e-07 31.6 5.4 0.00021 20.9 0.1 2.9 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase PF13246.6 CRK35605.1 - 0.00035 20.6 0.0 0.00092 19.3 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) HIGH_NTase1_ass PF16581.5 CRK35605.1 - 0.03 14.3 0.0 0.069 13.1 0.0 1.5 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region Hydrolase PF00702.26 CRK35605.1 - 0.051 13.9 0.2 0.18 12.0 0.0 2.0 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase DEADboxA PF12343.8 CRK35605.1 - 6.2 7.4 18.8 3.7 8.1 15.8 2.3 2 0 0 2 2 2 0 Cold shock protein DEAD box A DUF3684 PF12449.8 CRK35606.1 - 0 1615.2 0.5 5.5e-250 832.5 3.7 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3684) Sec16_C PF12931.7 CRK35606.1 - 4.7e-73 246.5 0.3 1.5e-45 156.2 0.0 2.5 1 1 1 2 2 2 2 Sec23-binding domain of Sec16 Sec16 PF12932.7 CRK35606.1 - 2.8e-32 111.8 0.1 1.7e-31 109.3 0.0 2.6 2 0 0 2 2 2 1 Vesicle coat trafficking protein Sec16 mid-region Reprolysin_5 PF13688.6 CRK35606.1 - 0.042 14.0 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12 RabGAP-TBC PF00566.18 CRK35607.1 - 2.6e-36 125.3 5.2 9.1e-36 123.5 5.2 1.9 1 1 0 1 1 1 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 CRK35607.1 - 5.8e-10 38.9 0.0 9.4e-05 21.9 0.0 3.3 3 0 0 3 3 3 3 Rab-binding domain (RBD) p450 PF00067.22 CRK35608.1 - 6.2e-12 45.0 0.0 3.9e-11 42.4 0.0 1.8 2 0 0 2 2 2 1 Cytochrome P450 DUF5401 PF17380.2 CRK35608.1 - 0.094 10.8 0.1 0.12 10.4 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Ribosomal_L28e PF01778.17 CRK35610.1 - 4.8e-37 127.2 0.6 9.5e-37 126.3 0.6 1.5 1 0 0 1 1 1 1 Ribosomal L28e protein family Mak16 PF04874.14 CRK35610.1 - 4.2e-25 88.3 17.2 4.2e-25 88.3 17.2 2.4 1 1 1 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 CRK35610.1 - 0.00014 21.4 17.9 0.00018 21.0 17.9 1.1 1 0 0 1 1 1 1 BUD22 Reovirus_cap PF00979.17 CRK35610.1 - 0.039 13.1 0.0 0.056 12.6 0.0 1.1 1 0 0 1 1 1 0 Reovirus outer capsid protein, Sigma 3 PYC_OADA PF02436.18 CRK35610.1 - 0.06 13.1 0.7 0.1 12.3 0.7 1.4 1 0 0 1 1 1 0 Conserved carboxylase domain TFIIF_alpha PF05793.12 CRK35610.1 - 6.4 5.2 31.1 10 4.6 31.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PPP4R2 PF09184.11 CRK35610.1 - 7.9 6.0 17.9 13 5.2 16.9 1.9 2 0 0 2 2 2 0 PPP4R2 TrmE_N PF10396.9 CRK35611.1 - 4e-36 123.8 0.0 1e-35 122.5 0.0 1.7 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MnmE_helical PF12631.7 CRK35611.1 - 1.6e-33 116.6 0.1 2.1e-33 116.3 0.1 1.1 1 0 0 1 1 1 1 MnmE helical domain MMR_HSR1 PF01926.23 CRK35611.1 - 3.6e-17 62.5 0.0 6.6e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CRK35611.1 - 0.00033 20.2 0.0 0.00064 19.3 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 CRK35611.1 - 0.0088 16.1 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 Dynamin family RsgA_GTPase PF03193.16 CRK35611.1 - 0.012 15.5 0.0 0.47 10.3 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase GTP_EFTU PF00009.27 CRK35611.1 - 0.04 13.4 0.0 0.19 11.3 0.0 1.9 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 CRK35611.1 - 0.071 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CRK35611.1 - 0.12 12.9 0.0 0.23 12.0 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Glyco_hydro_63 PF03200.16 CRK35613.1 - 1.3e-172 575.0 2.9 8.5e-172 572.3 0.1 2.7 2 1 0 2 2 2 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 CRK35613.1 - 1.4e-75 254.3 0.3 2.5e-74 250.2 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 CRK35613.1 - 1.5e-08 33.9 0.0 3.2e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Trehalase GDE_C PF06202.14 CRK35613.1 - 0.031 13.2 0.0 0.055 12.4 0.0 1.4 1 0 0 1 1 1 0 Amylo-alpha-1,6-glucosidase TRAPPC9-Trs120 PF08626.11 CRK35614.1 - 0 1316.8 0.0 4.8e-210 700.0 0.0 2.0 1 1 1 2 2 2 2 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Vps55 PF04133.14 CRK35616.1 - 2.1e-41 140.6 11.1 2.3e-41 140.4 11.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 DUF4349 PF14257.6 CRK35616.1 - 3.4 7.0 4.4 0.49 9.8 0.3 1.7 1 1 0 2 2 2 0 Domain of unknown function (DUF4349) DUF3684 PF12449.8 CRK35618.1 - 2.7e-159 532.1 0.0 1.9e-156 522.8 0.0 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3684) Proteasome PF00227.26 CRK35618.1 - 2.3e-17 63.1 0.1 4e-17 62.3 0.1 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CRK35618.1 - 1.7e-10 40.4 0.2 4.1e-10 39.2 0.2 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Reprolysin_5 PF13688.6 CRK35618.1 - 0.012 15.8 0.1 0.029 14.5 0.1 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12 RabGAP-TBC PF00566.18 CRK35620.1 - 1.1e-36 126.5 3.8 3.4e-36 124.9 3.8 1.9 1 1 0 1 1 1 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 CRK35620.1 - 4.8e-10 39.2 0.0 7.3e-05 22.3 0.0 3.3 3 0 0 3 3 3 3 Rab-binding domain (RBD) p450 PF00067.22 CRK35622.1 - 5e-62 210.2 0.0 6.2e-62 209.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 XH PF03469.14 CRK35622.1 - 0.096 12.6 0.1 0.23 11.4 0.1 1.6 1 0 0 1 1 1 0 XH domain La_HTH_kDCL PF18177.1 CRK35622.1 - 0.11 12.8 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 La HTH in kinetoplastid DICER domain DUF5401 PF17380.2 CRK35622.1 - 0.17 9.9 0.1 0.24 9.5 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Ribosomal_L28e PF01778.17 CRK35624.1 - 3.6e-37 127.6 0.6 7.2e-37 126.7 0.6 1.5 1 0 0 1 1 1 1 Ribosomal L28e protein family Mak16 PF04874.14 CRK35624.1 - 3e-25 88.7 17.5 3e-25 88.7 17.5 2.4 1 1 1 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 CRK35624.1 - 6.3e-05 22.5 18.4 7.8e-05 22.2 18.4 1.1 1 0 0 1 1 1 1 BUD22 Reovirus_cap PF00979.17 CRK35624.1 - 0.032 13.4 0.0 0.044 12.9 0.0 1.1 1 0 0 1 1 1 0 Reovirus outer capsid protein, Sigma 3 PYC_OADA PF02436.18 CRK35624.1 - 0.069 12.9 0.6 0.11 12.2 0.6 1.4 1 0 0 1 1 1 0 Conserved carboxylase domain TFIIF_alpha PF05793.12 CRK35624.1 - 0.11 11.1 31.0 0.17 10.5 31.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) UPF0524 PF15823.5 CRK35624.1 - 1.6 8.1 5.0 2.5 7.4 5.0 1.3 1 0 0 1 1 1 0 UPF0524 of C3orf70 MnmE_helical PF12631.7 CRK35626.1 - 1.2e-30 107.2 0.2 1.6e-30 106.8 0.2 1.1 1 0 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 CRK35626.1 - 6.9e-23 81.2 0.0 2e-22 79.7 0.0 1.8 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 CRK35626.1 - 3.1e-17 62.7 0.0 5e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CRK35626.1 - 0.00026 20.6 0.0 0.00049 19.7 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CRK35626.1 - 0.0081 16.1 0.0 0.38 10.6 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 CRK35626.1 - 0.0084 16.2 0.0 0.013 15.6 0.0 1.4 1 0 0 1 1 1 1 Dynamin family AAA_24 PF13479.6 CRK35626.1 - 0.057 13.1 0.0 0.099 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 CRK35626.1 - 0.097 12.2 0.0 0.47 10.0 0.0 1.9 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 CRK35626.1 - 0.1 13.1 0.0 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Glyco_hydro_63 PF03200.16 CRK35632.1 - 2.5e-173 577.4 2.6 1.9e-172 574.4 0.1 2.7 2 1 0 2 2 2 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 CRK35632.1 - 2.4e-75 253.5 0.5 2.3e-74 250.3 0.1 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 CRK35632.1 - 1.1e-08 34.4 0.1 2.3e-08 33.3 0.1 1.4 1 0 0 1 1 1 1 Trehalase GDE_C PF06202.14 CRK35632.1 - 0.01 14.8 0.0 0.018 14.0 0.0 1.4 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase TRAPPC9-Trs120 PF08626.11 CRK35634.1 - 0 1376.9 0.0 0 1376.7 0.0 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Proteasome PF00227.26 CRK35634.1 - 4e-62 209.1 0.1 1.4e-45 155.1 0.1 2.3 1 1 1 2 2 2 2 Proteasome subunit Chorismate_bind PF00425.18 CRK35634.1 - 4.7e-26 91.9 0.0 8.1e-26 91.1 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 CRK35634.1 - 1.6e-23 83.5 0.0 7.8e-23 81.2 0.0 2.1 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 CRK35634.1 - 1.2e-12 48.2 0.0 2.5e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Proteasome_A_N PF10584.9 CRK35634.1 - 4.7e-10 39.0 1.2 1.1e-09 37.7 0.2 2.2 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Peptidase_C26 PF07722.13 CRK35634.1 - 0.00085 19.1 0.1 0.023 14.5 0.1 3.1 3 1 0 3 3 3 1 Peptidase C26 Vps55 PF04133.14 CRK35638.1 - 1.1e-44 151.1 8.9 1.3e-44 150.9 8.9 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 DUF4349 PF14257.6 CRK35638.1 - 2.7 7.4 3.9 0.62 9.5 0.4 1.7 1 1 0 2 2 2 0 Domain of unknown function (DUF4349) Lysine_decarbox PF03641.14 CRK35639.1 - 4.5e-11 43.0 0.0 6.1e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Possible lysine decarboxylase DUF543 PF04418.12 CRK35639.1 - 0.024 14.6 0.2 0.045 13.8 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF543) Lysine_decarbox PF03641.14 CRK35640.1 - 1.1e-26 93.4 0.0 1.6e-26 92.9 0.0 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 CRK35640.1 - 3.6e-05 23.4 3.1 0.00012 21.6 3.0 1.9 1 1 0 1 1 1 1 SLOG cluster4 family DAGK_cat PF00781.24 CRK35640.1 - 0.1 12.2 0.9 6.3 6.4 0.1 2.3 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain CLPTM1 PF05602.12 CRK35641.1 - 1.2e-21 77.3 0.0 1.4e-21 77.0 0.0 1.0 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) DUF4971 PF16341.5 CRK35641.1 - 0.19 11.5 0.0 0.36 10.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4971) CLPTM1 PF05602.12 CRK35642.1 - 4.3e-197 655.3 0.0 5e-100 335.5 1.6 3.1 1 1 2 3 3 3 3 Cleft lip and palate transmembrane protein 1 (CLPTM1) DUF2093 PF09866.9 CRK35642.1 - 0.00049 19.5 0.5 15 5.1 0.0 3.6 3 0 0 3 3 3 3 Uncharacterized protein conserved in bacteria (DUF2093) DUF1772 PF08592.11 CRK35642.1 - 1.6 9.1 4.6 1.9 8.8 1.2 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) Pilosulin PF17499.2 CRK35642.1 - 5.8 7.2 5.7 8.3 6.7 3.5 2.3 2 0 0 2 2 2 0 Ant venom peptides Elong_Iki1 PF10483.9 CRK35643.1 - 1.4e-98 330.1 0.0 1.6e-97 326.6 0.0 2.3 2 0 0 2 2 2 1 Elongator subunit Iki1 Sugar_tr PF00083.24 CRK35643.1 - 2.2e-56 191.7 7.5 2.9e-56 191.2 7.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter ASXH PF13919.6 CRK35643.1 - 7.8e-35 119.9 0.1 1.5e-34 119.0 0.1 1.5 1 0 0 1 1 1 1 Asx homology domain MFS_1 PF07690.16 CRK35643.1 - 2.8e-16 59.4 11.1 4.7e-16 58.7 11.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily SNRNP27 PF08648.12 CRK35645.1 - 5.8e-28 96.7 2.4 1.2e-27 95.7 2.4 1.6 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins Longin PF13774.6 CRK35645.1 - 3e-16 59.2 0.0 4.7e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain adh_short PF00106.25 CRK35646.1 - 2.5e-18 66.2 0.0 4.2e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK35646.1 - 3.4e-16 59.5 0.0 5e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Aminotran_5 PF00266.19 CRK35647.1 - 6.2e-28 97.8 0.0 3e-17 62.6 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V VAPB_antitox PF02697.14 CRK35647.1 - 0.027 15.2 0.0 0.052 14.3 0.0 1.5 1 0 0 1 1 1 0 Putative antitoxin PheRS_DBD2 PF18554.1 CRK35647.1 - 0.14 12.2 0.4 2.1 8.4 0.1 2.7 2 0 0 2 2 2 0 PheRS DNA binding domain 2 Sugar_tr PF00083.24 CRK35648.1 - 2.9e-120 402.2 27.0 3.4e-120 402.0 27.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK35648.1 - 1.5e-18 66.9 24.9 1.5e-18 66.9 24.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2264 PF10022.9 CRK35649.1 - 6.1e-135 449.9 0.0 7.8e-135 449.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) HNH_2 PF13391.6 CRK35650.1 - 3.3e-12 46.4 0.0 7.4e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease Cutinase PF01083.22 CRK35650.1 - 0.17 11.8 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Cutinase Hus1 PF04005.12 CRK35652.1 - 7.7e-89 297.7 0.0 8.7e-89 297.5 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein CymA PF16941.5 CRK35652.1 - 0.12 11.6 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 Putative cyclodextrin porin MMtag PF10159.9 CRK35653.1 - 1.1e-31 108.9 0.8 1.1e-31 108.9 0.8 3.3 2 1 0 2 2 2 1 Multiple myeloma tumor-associated Med6 PF04934.14 CRK35654.1 - 1e-34 119.2 0.0 1.3e-34 118.8 0.0 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component HA2 PF04408.23 CRK35655.1 - 5.8e-26 90.9 0.1 5.8e-26 90.9 0.1 2.7 4 0 0 4 4 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CRK35655.1 - 4e-12 46.3 0.0 9.2e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CRK35655.1 - 1.3e-11 44.8 0.1 9.2e-11 42.1 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CRK35655.1 - 1.1e-09 38.3 0.1 2.8e-09 37.0 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 CRK35655.1 - 4.9e-05 23.7 0.1 0.00014 22.2 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CRK35655.1 - 9.7e-05 22.7 0.0 0.00034 20.9 0.0 1.9 2 0 0 2 2 1 1 AAA domain T2SSE PF00437.20 CRK35655.1 - 0.0003 20.0 0.1 0.0041 16.2 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.6 CRK35655.1 - 0.002 17.9 0.0 0.004 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 CRK35655.1 - 0.039 13.4 0.1 0.096 12.1 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein DUF2075 PF09848.9 CRK35655.1 - 0.049 12.9 0.0 0.049 12.9 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ATPase PF06745.13 CRK35655.1 - 0.1 11.9 0.0 0.1 11.9 0.0 2.4 3 0 0 3 3 3 0 KaiC AAA_23 PF13476.6 CRK35655.1 - 0.17 12.4 0.0 0.17 12.4 0.0 2.7 3 0 0 3 3 3 0 AAA domain Cyclase PF04199.13 CRK35656.1 - 2.6e-13 50.4 0.1 3.8e-13 49.8 0.1 1.3 1 0 0 1 1 1 1 Putative cyclase Metallophos PF00149.28 CRK35657.1 - 1.8e-37 129.9 0.0 3.2e-37 129.0 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TauD PF02668.16 CRK35658.1 - 3.5e-40 138.5 0.0 5.1e-40 138.0 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 CRK35658.1 - 2e-12 47.6 0.0 3.9e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF971) DUF3421 PF11901.8 CRK35659.1 - 0.08 12.9 0.0 2.2 8.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3421) ABC_export PF16962.5 CRK35659.1 - 0.21 10.0 0.2 0.33 9.4 0.2 1.2 1 0 0 1 1 1 0 Putative ABC exporter PhoD PF09423.10 CRK35660.1 - 4.2e-26 91.8 0.0 2e-23 83.0 0.0 2.1 1 1 1 2 2 2 2 PhoD-like phosphatase EMP24_GP25L PF01105.24 CRK35661.1 - 2.2e-45 154.8 2.0 2.5e-45 154.6 2.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Kin17_mid PF10357.9 CRK35662.1 - 3.6e-52 175.6 0.6 3.6e-52 175.6 0.6 1.9 3 0 0 3 3 3 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.8 CRK35662.1 - 0.013 15.8 2.3 0.013 15.8 2.3 1.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 CRK35662.1 - 0.025 14.9 3.0 0.035 14.4 0.5 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 CRK35662.1 - 0.051 14.0 2.9 0.1 13.0 2.9 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Spt4 PF06093.13 CRK35663.1 - 3.7e-32 110.3 0.2 4.6e-32 110.0 0.2 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger TBCC PF07986.12 CRK35663.1 - 0.05 13.3 0.5 0.065 13.0 0.5 1.2 1 0 0 1 1 1 0 Tubulin binding cofactor C Zn_ribbon_17 PF17120.5 CRK35663.1 - 0.077 12.6 0.9 0.13 11.9 0.9 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Coronavirus_5 PF05528.11 CRK35663.1 - 0.12 12.4 0.3 0.41 10.7 0.1 1.9 1 1 1 2 2 2 0 Coronavirus gene 5 protein Es2 PF09751.9 CRK35666.1 - 1.6e-121 407.0 10.9 2e-121 406.8 10.9 1.1 1 0 0 1 1 1 1 Nuclear protein Es2 ABC1 PF03109.16 CRK35667.1 - 4.8e-32 110.6 0.0 8.9e-32 109.7 0.0 1.5 1 0 0 1 1 1 1 ABC1 family RRP36 PF06102.12 CRK35668.1 - 1.1e-55 188.1 30.9 1.1e-55 188.1 30.9 2.2 2 1 0 2 2 2 1 rRNA biogenesis protein RRP36 NIF PF03031.18 CRK35669.1 - 7.9e-18 64.7 0.0 1.1e-17 64.2 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase EF1G PF00647.19 CRK35670.1 - 7.6e-43 144.9 0.0 1.3e-42 144.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 CRK35670.1 - 1.1e-13 51.2 0.0 2.3e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CRK35670.1 - 4.3e-09 36.6 0.1 1.2e-08 35.1 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CRK35670.1 - 1e-06 28.7 0.2 5e-06 26.4 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CRK35670.1 - 8.5e-05 22.7 0.0 0.00023 21.3 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DEC-1_N PF04625.13 CRK35670.1 - 0.012 14.7 4.6 0.017 14.2 4.6 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region GST_N_3 PF13417.6 CRK35670.1 - 0.052 14.0 0.0 0.14 12.6 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 CRK35670.1 - 0.074 12.9 0.0 0.5 10.2 0.0 2.2 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Ribosomal_S9 PF00380.19 CRK35671.1 - 1e-41 142.2 0.4 2e-41 141.3 0.4 1.5 1 0 0 1 1 1 1 Ribosomal protein S9/S16 OCRE PF17780.1 CRK35672.1 - 0.043 13.8 0.0 0.088 12.9 0.0 1.5 1 0 0 1 1 1 0 OCRE domain ArgoL1 PF08699.10 CRK35672.1 - 0.062 13.0 0.0 0.19 11.4 0.0 1.9 1 0 0 1 1 1 0 Argonaute linker 1 domain OCRE PF17780.1 CRK35673.1 - 0.051 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 OCRE domain ArgoL1 PF08699.10 CRK35673.1 - 0.08 12.6 0.0 0.24 11.1 0.0 1.8 1 0 0 1 1 1 0 Argonaute linker 1 domain SOG2 PF10428.9 CRK35673.1 - 0.9 8.7 5.2 1.1 8.4 5.2 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein MDMPI_C PF07398.11 CRK35674.1 - 0.092 13.6 1.0 0.092 13.6 1.0 1.9 2 0 0 2 2 2 0 MDMPI C-terminal domain EF-hand_1 PF00036.32 CRK35675.1 - 5e-25 85.1 15.1 5.1e-07 28.8 1.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CRK35675.1 - 3.4e-21 75.5 14.9 3.1e-13 49.9 1.9 2.7 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 CRK35675.1 - 7.8e-19 65.9 8.5 0.00014 21.5 0.2 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CRK35675.1 - 6.5e-16 57.0 13.4 1.1e-05 24.7 0.7 4.3 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 CRK35675.1 - 6.8e-11 41.8 12.5 0.00013 21.7 0.9 4.2 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 CRK35675.1 - 1.6e-05 25.1 0.1 0.015 15.6 0.1 2.4 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 CRK35675.1 - 0.00019 21.3 10.1 0.0064 16.4 0.7 3.9 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand Anillin PF08174.11 CRK35675.1 - 0.04 14.4 0.1 12 6.3 0.0 2.9 2 1 1 3 3 3 0 Cell division protein anillin Dockerin_1 PF00404.18 CRK35675.1 - 0.07 13.3 1.4 0.26 11.5 1.4 2.1 1 1 0 1 1 1 0 Dockerin type I domain EPL1 PF10513.9 CRK35676.1 - 2.2e-21 76.9 2.0 2.2e-21 76.9 2.0 1.9 2 0 0 2 2 2 1 Enhancer of polycomb-like Peptidase_M22 PF00814.25 CRK35677.1 - 2.2e-100 335.9 0.3 5e-49 167.4 0.1 2.1 2 0 0 2 2 2 2 Glycoprotease family Staygreen PF12638.7 CRK35677.1 - 0.011 15.6 0.0 7.1 6.4 0.0 2.4 2 0 0 2 2 2 0 Staygreen protein AMPK1_CBM PF16561.5 CRK35678.1 - 2e-25 88.8 0.0 3e-25 88.3 0.0 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Pkinase PF00069.25 CRK35680.1 - 1.3e-64 218.2 0.0 1.6e-64 217.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK35680.1 - 4.9e-30 104.7 0.0 6.8e-30 104.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CRK35680.1 - 0.0083 15.5 0.0 0.021 14.2 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CRK35680.1 - 0.012 14.4 0.0 0.017 13.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 CRK35680.1 - 0.039 12.9 0.0 0.089 11.7 0.0 1.5 1 1 0 1 1 1 0 Haspin like kinase domain DNA_pol_B_exo1 PF03104.19 CRK35681.1 - 1.3e-119 399.3 0.1 9.8e-66 222.2 0.0 3.4 2 1 1 3 3 3 3 DNA polymerase family B, exonuclease domain Asparaginase PF00710.20 CRK35681.1 - 3.9e-57 192.9 0.0 7.9e-57 191.9 0.0 1.6 1 0 0 1 1 1 1 Asparaginase, N-terminal Rhomboid PF01694.22 CRK35681.1 - 1.7e-35 122.2 7.2 4.8e-35 120.8 7.2 1.8 1 0 0 1 1 1 1 Rhomboid family GARS_A PF01071.19 CRK35681.1 - 5.9e-32 111.0 0.0 1.2e-31 110.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Asparaginase_C PF17763.1 CRK35681.1 - 4.4e-24 84.9 0.0 8.6e-24 84.0 0.0 1.5 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain EPL1 PF10513.9 CRK35681.1 - 1.8e-17 64.2 1.7 8.9e-17 61.9 1.7 2.3 1 0 0 1 1 1 1 Enhancer of polycomb-like DNA_pol_B_exo2 PF10108.9 CRK35681.1 - 3.3e-07 30.2 0.1 0.0084 15.8 0.0 2.4 2 0 0 2 2 2 2 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB Ank_2 PF12796.7 CRK35681.1 - 4.8e-06 27.1 0.1 1.1e-05 25.9 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) RNase_H_2 PF13482.6 CRK35681.1 - 6.5e-05 23.0 0.4 0.063 13.3 0.1 3.3 2 1 0 2 2 2 1 RNase_H superfamily ATP-grasp PF02222.22 CRK35681.1 - 0.00019 21.0 0.0 0.0004 20.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain DUF1948 PF09185.10 CRK35681.1 - 0.00022 21.1 0.2 0.99 9.3 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF1948) Ank PF00023.30 CRK35681.1 - 0.0047 17.3 0.0 0.019 15.4 0.0 2.1 1 0 0 1 1 1 1 Ankyrin repeat DNA_pol_B PF00136.21 CRK35681.1 - 0.007 15.1 0.0 0.011 14.4 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B FeThRed_B PF02943.15 CRK35681.1 - 0.035 14.1 0.4 0.078 13.0 0.4 1.5 1 0 0 1 1 1 0 Ferredoxin thioredoxin reductase catalytic beta chain DUF1772 PF08592.11 CRK35681.1 - 0.074 13.4 1.6 16 5.8 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) ATP-grasp_4 PF13535.6 CRK35681.1 - 0.11 12.0 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain VKOR PF07884.14 CRK35681.1 - 0.18 12.0 8.3 3.7 7.7 1.6 2.6 2 0 0 2 2 2 0 Vitamin K epoxide reductase family Sdh_cyt PF01127.22 CRK35681.1 - 0.35 10.9 9.3 4.2 7.4 0.8 2.6 2 0 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit AMPKBI PF04739.15 CRK35682.1 - 3.2e-26 91.4 1.8 4.3e-26 91.0 1.8 1.2 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain AMPK1_CBM PF16561.5 CRK35683.1 - 2.7e-25 88.4 0.0 5.4e-25 87.4 0.0 1.5 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 CRK35683.1 - 9e-25 86.7 1.8 9e-25 86.7 1.8 2.5 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interaction domain Pkinase PF00069.25 CRK35685.1 - 4.9e-60 203.1 0.0 3.1e-52 177.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CRK35685.1 - 8.5e-27 94.1 0.0 9.1e-23 80.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CRK35685.1 - 0.0095 15.3 0.0 0.017 14.4 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CRK35685.1 - 0.011 14.6 0.0 0.016 14.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 CRK35685.1 - 0.17 10.8 0.0 0.41 9.5 0.0 1.5 1 1 0 1 1 1 0 Haspin like kinase domain Asparaginase PF00710.20 CRK35686.1 - 4.4e-37 127.5 0.0 2e-27 96.0 0.0 2.3 1 1 1 2 2 2 2 Asparaginase, N-terminal Asparaginase_C PF17763.1 CRK35686.1 - 3.4e-25 88.5 0.0 7.7e-25 87.3 0.0 1.6 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ank_2 PF12796.7 CRK35686.1 - 5e-11 43.0 0.2 3.8e-07 30.6 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 CRK35686.1 - 1.5e-07 31.5 0.0 0.0035 17.7 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 CRK35686.1 - 0.00063 20.3 0.1 0.33 11.6 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CRK35686.1 - 0.0012 19.1 0.0 39 5.3 0.0 4.3 4 0 0 4 4 4 0 Ankyrin repeat Ank_5 PF13857.6 CRK35686.1 - 0.058 13.7 0.1 0.32 11.4 0.2 2.2 3 0 0 3 3 3 0 Ankyrin repeats (many copies) GARS_A PF01071.19 CRK35687.1 - 2.1e-54 184.2 0.0 4.4e-54 183.2 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 CRK35687.1 - 4.3e-29 101.2 0.1 9.4e-29 100.1 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 CRK35687.1 - 6.6e-17 61.6 0.2 1.8e-16 60.2 0.2 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain ATP-grasp PF02222.22 CRK35687.1 - 4.3e-05 23.2 0.0 9.8e-05 22.0 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 CRK35687.1 - 0.0038 16.7 0.0 0.0069 15.9 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.14 CRK35687.1 - 0.014 15.5 0.0 0.042 13.9 0.0 1.8 2 0 0 2 2 2 0 ATP-grasp domain ATP-grasp_5 PF13549.6 CRK35687.1 - 0.087 12.3 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain DNA_pol_B PF00136.21 CRK35688.1 - 2.5e-140 468.2 2.2 3.3e-140 467.9 2.2 1.1 1 0 0 1 1 1 1 DNA polymerase family B Rhomboid PF01694.22 CRK35688.1 - 2.1e-19 70.0 1.4 4.3e-19 69.0 1.4 1.4 1 0 0 1 1 1 1 Rhomboid family DNA_pol_B_2 PF03175.13 CRK35688.1 - 0.00087 18.3 0.7 0.028 13.3 0.1 2.3 2 1 0 2 2 2 2 DNA polymerase type B, organellar and viral FeThRed_B PF02943.15 CRK35688.1 - 0.0035 17.3 0.3 0.0082 16.1 0.3 1.5 1 0 0 1 1 1 1 Ferredoxin thioredoxin reductase catalytic beta chain ELFV_dehydrog PF00208.21 CRK35690.1 - 1.7e-82 276.8 3.0 3.4e-82 275.8 3.0 1.6 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 CRK35690.1 - 9.9e-49 164.5 0.0 3.6e-48 162.7 0.0 2.0 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain GMC_oxred_C PF05199.13 CRK35690.1 - 2.3e-18 67.1 3.3 5.2e-08 33.5 0.1 3.5 4 0 0 4 4 4 2 GMC oxidoreductase HA2 PF04408.23 CRK35690.1 - 3.2e-16 59.6 0.0 1.4e-15 57.4 0.0 2.2 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CRK35690.1 - 9.8e-16 58.1 0.0 2.1e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 CRK35690.1 - 1.3e-10 41.5 0.0 4.9e-10 39.6 0.0 2.0 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold GhoS PF11080.8 CRK35690.1 - 0.00071 19.5 0.0 2.3 8.3 0.0 2.6 2 0 0 2 2 2 2 Endoribonuclease GhoS NAD_binding_7 PF13241.6 CRK35690.1 - 0.12 12.9 1.2 1.1 9.7 0.1 3.2 3 0 0 3 3 3 0 Putative NAD(P)-binding DNA_pol_B PF00136.21 CRK35691.1 - 6.3e-57 193.3 0.2 8.6e-57 192.9 0.2 1.1 1 0 0 1 1 1 1 DNA polymerase family B zf-C4pol PF14260.6 CRK35691.1 - 5.2e-17 62.1 7.5 9e-17 61.3 7.5 1.4 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DUF2614 PF11023.8 CRK35691.1 - 0.0091 16.1 0.2 0.019 15.1 0.2 1.4 1 0 0 1 1 1 1 Zinc-ribbon containing domain C1_1 PF00130.22 CRK35691.1 - 0.98 9.4 9.8 0.52 10.2 1.1 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) GMC_oxred_N PF00732.19 CRK35692.1 - 7.3e-08 32.1 0.0 2.1e-07 30.6 0.0 1.8 1 1 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 CRK35692.1 - 0.05 13.8 0.1 0.13 12.5 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CRK35692.1 - 0.1 11.6 0.1 0.23 10.5 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.14 CRK35692.1 - 0.12 11.5 0.1 0.25 10.5 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ELFV_dehydrog PF00208.21 CRK35694.1 - 2.7e-82 276.1 2.8 4.8e-82 275.3 2.8 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Cyclin_N PF00134.23 CRK35694.1 - 4.6e-42 142.8 0.1 1.2e-41 141.4 0.1 1.8 1 0 0 1 1 1 1 Cyclin, N-terminal domain ELFV_dehydrog_N PF02812.18 CRK35694.1 - 8.4e-37 126.0 0.0 2.1e-36 124.7 0.0 1.6 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Cyclin_C PF02984.19 CRK35694.1 - 4.2e-34 117.2 0.1 8.9e-34 116.1 0.1 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain Helicase_C PF00271.31 CRK35694.1 - 1.1e-15 57.9 0.0 2.6e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 CRK35694.1 - 1.8e-15 57.1 0.0 1.8e-15 57.1 0.0 2.9 3 0 0 3 3 2 1 Helicase associated domain (HA2) DEAD PF00270.29 CRK35694.1 - 1.3e-11 44.6 0.4 3.3e-11 43.3 0.4 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 CRK35694.1 - 3.6e-10 40.1 0.0 8.9e-10 38.8 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold TRAP_alpha PF03896.16 CRK35694.1 - 5.1e-08 32.5 0.0 1.3e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit dsRBD2 PF17842.1 CRK35694.1 - 0.00012 22.3 0.1 1.1 9.5 0.0 2.8 2 0 0 2 2 2 2 Double-stranded RNA binding domain 2 DND1_DSRM PF14709.7 CRK35694.1 - 0.00032 20.9 5.5 0.5 10.7 0.3 3.7 3 0 0 3 3 2 2 double strand RNA binding domain from DEAD END PROTEIN 1 RWD PF05773.22 CRK35694.1 - 0.012 15.9 0.0 0.026 14.8 0.0 1.6 1 0 0 1 1 1 0 RWD domain ATPase PF06745.13 CRK35694.1 - 0.022 14.1 0.1 0.051 12.9 0.1 1.5 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.6 CRK35694.1 - 0.028 14.7 0.3 0.1 12.9 0.3 1.9 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CRK35694.1 - 0.034 13.9 0.0 0.096 12.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain GHMP_kinases_C PF08544.13 CRK35694.1 - 0.049 14.0 0.0 13 6.2 0.0 3.0 2 0 0 2 2 2 0 GHMP kinases C terminal AAA_25 PF13481.6 CRK35694.1 - 0.051 13.1 0.0 0.16 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 CRK35694.1 - 0.063 12.3 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Rap1-DNA-bind PF09197.10 CRK35694.1 - 0.11 13.1 0.3 8.8 7.0 0.1 2.8 2 0 0 2 2 2 0 Rap1, DNA-binding AT_hook PF02178.19 CRK35694.1 - 6.2 7.1 39.2 0.82 9.8 4.0 5.1 4 0 0 4 4 4 0 AT hook motif InPase PF18823.1 CRK35694.1 - 7.6 6.2 9.3 17 5.1 1.4 2.5 2 0 0 2 2 2 0 Inorganic Pyrophosphatase HIT PF01230.23 CRK35695.1 - 5.7e-17 62.3 2.2 1.6e-16 60.8 2.2 1.8 1 1 0 1 1 1 1 HIT domain DcpS_C PF11969.8 CRK35695.1 - 6.9e-14 52.3 6.1 5.5e-13 49.4 6.1 2.0 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding zf-C2HE PF16278.5 CRK35696.1 - 2e-17 63.4 0.6 5.6e-17 61.9 0.6 1.8 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger HIT PF01230.23 CRK35696.1 - 3.1e-17 63.1 1.5 8e-17 61.8 1.5 1.7 1 1 0 1 1 1 1 HIT domain DcpS_C PF11969.8 CRK35696.1 - 3.9e-15 56.3 8.8 5.2e-14 52.7 8.8 2.1 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Zn_clus PF00172.18 CRK35697.1 - 0.00057 20.0 12.5 0.001 19.1 12.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHZ PF09649.10 CRK35697.1 - 0.00098 18.5 0.2 0.0054 16.2 0.0 2.3 2 0 0 2 2 2 1 Histone chaperone domain CHZ Abhydrolase_6 PF12697.7 CRK35698.1 - 5.5e-07 30.4 3.1 7.3e-07 30.0 3.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 CRK35698.1 - 0.00012 22.0 3.9 0.0063 16.4 0.4 3.3 3 1 0 3 3 3 1 alpha/beta hydrolase fold Thioesterase PF00975.20 CRK35698.1 - 0.015 15.4 0.1 0.025 14.7 0.1 1.3 1 0 0 1 1 1 0 Thioesterase domain Hydrolase_4 PF12146.8 CRK35698.1 - 0.044 13.1 0.1 0.34 10.1 0.0 2.0 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF3089 PF11288.8 CRK35698.1 - 0.066 12.8 0.1 0.27 10.7 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3089) DUF915 PF06028.11 CRK35698.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) RNA_pol_Rpc4 PF05132.14 CRK35701.1 - 2e-31 109.4 0.0 2e-31 109.4 0.0 3.6 3 2 1 4 4 4 1 RNA polymerase III RPC4 Keratin_2_head PF16208.5 CRK35701.1 - 1.4 9.0 24.9 4.3 7.5 24.9 1.8 1 0 0 1 1 1 0 Keratin type II head TPPII_N PF12583.8 CRK35701.1 - 1.8 9.2 9.1 3.7 8.1 8.4 1.9 1 1 0 1 1 1 0 Tripeptidyl peptidase II N terminal TMA7 PF09072.10 CRK35701.1 - 3.4 8.6 11.8 0.88 10.5 0.5 3.6 3 0 0 3 3 3 0 Translation machinery associated TMA7 UreD PF01774.17 CRK35702.1 - 1.6e-76 256.9 0.3 1.9e-76 256.7 0.3 1.1 1 0 0 1 1 1 1 UreD urease accessory protein STAG PF08514.11 CRK35703.1 - 3.7e-34 117.0 0.3 1.5e-33 115.0 0.3 2.2 1 0 0 1 1 1 1 STAG domain HEAT_2 PF13646.6 CRK35703.1 - 0.00091 19.6 1.4 0.52 10.7 0.0 3.5 2 1 2 4 4 4 3 HEAT repeats HEAT PF02985.22 CRK35703.1 - 0.0012 18.9 0.2 22 5.7 0.0 4.7 4 0 0 4 4 4 2 HEAT repeat POT1PC PF16686.5 CRK35704.1 - 4.7e-39 133.7 0.1 7.7e-39 133.1 0.1 1.3 1 0 0 1 1 1 1 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 CRK35704.1 - 2.4e-14 53.3 0.0 1.1e-13 51.3 0.0 2.0 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 Med5 PF08689.10 CRK35705.1 - 1.3e-138 463.6 0.0 4.6e-92 309.6 0.0 3.4 1 1 1 2 2 2 2 Mediator complex subunit Med5 IBB PF01749.20 CRK35705.1 - 0.0089 16.4 0.0 0.02 15.3 0.0 1.6 1 0 0 1 1 1 1 Importin beta binding domain DUF2710 PF10921.8 CRK35705.1 - 0.016 15.6 3.4 11 6.5 0.0 4.2 5 0 0 5 5 5 0 Protein of unknown function (DUF2710) SSF PF00474.17 CRK35705.1 - 0.056 12.3 0.4 0.098 11.5 0.4 1.3 1 0 0 1 1 1 0 Sodium:solute symporter family DJ-1_PfpI PF01965.24 CRK35705.1 - 0.13 12.1 0.1 0.23 11.2 0.1 1.4 1 0 0 1 1 1 0 DJ-1/PfpI family DUF3453 PF11935.8 CRK35705.1 - 0.19 11.3 0.8 24 4.5 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3453) Mito_carr PF00153.27 CRK35706.1 - 4.4e-115 375.9 4.7 2.9e-25 88.0 0.0 6.7 6 0 0 6 6 6 5 Mitochondrial carrier protein PQ-loop PF04193.14 CRK35706.1 - 2.5e-59 196.9 28.6 3.4e-15 55.5 2.6 4.6 4 0 0 4 4 4 4 PQ loop repeat EF-hand_7 PF13499.6 CRK35706.1 - 3.8e-15 56.1 3.7 1.1e-07 32.2 0.5 3.4 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 CRK35706.1 - 2.7e-12 45.6 0.9 4.5e-06 26.2 0.2 4.7 6 0 0 6 6 6 2 EF-hand domain EF-hand_1 PF00036.32 CRK35706.1 - 3.4e-12 45.0 1.1 5.8e-06 25.5 0.4 4.8 4 0 0 4 4 4 2 EF hand EF-hand_5 PF13202.6 CRK35706.1 - 8.7e-10 37.6 1.3 3.1e-06 26.4 1.1 3.6 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 CRK35706.1 - 2.2e-06 27.4 3.6 2.6 7.9 0.0 5.2 5 0 0 5 5 5 2 EF-hand domain pair Vma12 PF11712.8 CRK35706.1 - 0.00018 21.6 0.7 0.67 10.0 0.1 2.5 2 0 0 2 2 2 2 Endoplasmic reticulum-based factor for assembly of V-ATPase HPP PF04982.13 CRK35706.1 - 0.32 11.2 13.0 0.56 10.4 0.2 3.6 4 0 0 4 4 4 0 HPP family Phage_holin_8 PF16931.5 CRK35706.1 - 1.9 8.5 5.9 4.2 7.4 0.6 2.7 2 0 0 2 2 2 0 Putative phage holin DUF3123 PF11321.8 CRK35706.1 - 7.6 7.2 6.1 61 4.3 0.0 3.4 3 0 0 3 3 2 0 Protein of unknown function (DUF3123) GATase_4 PF13230.6 CRK35707.1 - 3.7e-17 62.1 0.1 5.3e-15 55.1 0.1 2.2 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 CRK35707.1 - 1.4e-08 35.0 0.0 2.5e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF4064 PF13273.6 CRK35708.1 - 0.043 14.1 2.0 0.63 10.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) FA_desaturase PF00487.24 CRK35708.1 - 0.24 11.2 7.2 0.37 10.6 7.2 1.3 1 0 0 1 1 1 0 Fatty acid desaturase KcnmB2_inactiv PF09303.10 CRK35711.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 KCNMB2, ball and chain domain tRNA-synt_2c PF01411.19 CRK35716.1 - 1.3e-12 47.1 0.0 1.8e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 CRK35716.1 - 2.5e-05 24.3 0.1 4.9e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TauD PF02668.16 CRK35717.1 - 1.9e-30 106.6 0.1 3.2e-30 105.8 0.1 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DOT1 PF08123.13 CRK35718.1 - 1.5e-74 249.9 0.0 2.1e-74 249.5 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 VbhA PF18495.1 CRK35720.1 - 0.1 12.5 0.1 0.21 11.5 0.1 1.5 1 0 0 1 1 1 0 Antitoxin VbhA RTP1_C2 PF10304.9 CRK35720.1 - 0.16 11.7 0.4 0.16 11.7 0.4 2.1 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 2 Vps16_N PF04841.13 CRK35721.1 - 5.2e-86 289.0 0.0 7.5e-86 288.4 0.0 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 CRK35721.1 - 6e-86 288.4 0.0 8.6e-86 287.9 0.0 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region ANAPC4_WD40 PF12894.7 CRK35721.1 - 0.0026 18.0 0.0 0.13 12.6 0.0 3.2 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain FHA PF00498.26 CRK35722.1 - 7.4e-15 55.1 0.0 1.4e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 CRK35722.1 - 1e-13 50.7 5.9 1.8e-13 50.0 5.9 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 CRK35722.1 - 2.6e-07 30.8 9.2 4.3e-07 30.2 9.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CRK35722.1 - 0.0012 18.7 9.3 0.002 18.0 9.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CRK35722.1 - 0.002 18.0 6.9 0.0033 17.4 6.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain PHD PF00628.29 CRK35722.1 - 0.013 15.4 5.2 0.024 14.6 5.2 1.5 1 0 0 1 1 1 0 PHD-finger Yop-YscD_cpl PF16697.5 CRK35722.1 - 0.013 15.8 0.0 0.028 14.7 0.0 1.4 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain zf-rbx1 PF12678.7 CRK35722.1 - 0.014 15.7 8.5 0.033 14.5 8.5 1.6 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 CRK35722.1 - 0.016 15.2 8.3 0.033 14.2 8.3 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CRK35722.1 - 0.018 14.9 8.7 0.031 14.1 8.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CRK35722.1 - 0.029 14.4 2.1 0.055 13.5 2.1 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-HC5HC2H_2 PF13832.6 CRK35722.1 - 0.11 12.7 1.3 0.2 11.8 1.3 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 CRK35722.1 - 0.27 11.5 2.7 0.49 10.7 2.7 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-C3HC4_4 PF15227.6 CRK35722.1 - 1.5 9.0 6.2 3.7 7.8 6.2 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.11 CRK35722.1 - 3.4 8.1 6.0 6.4 7.2 6.0 1.5 1 0 0 1 1 1 0 RING-like domain Peptidase_M16_C PF05193.21 CRK35723.1 - 3.3e-55 186.9 0.0 5e-55 186.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 CRK35723.1 - 3.7e-43 147.1 0.0 1.4e-41 142.0 0.0 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) S1 PF00575.23 CRK35725.1 - 1e-41 141.1 24.7 9e-12 45.2 0.0 10.2 10 1 0 10 10 10 8 S1 RNA binding domain RNase_II_C_S1 PF18614.1 CRK35725.1 - 0.0096 15.9 8.6 12 5.9 0.1 5.9 6 0 0 6 6 6 2 RNase II-type exonuclease C-terminal S1 domain PilZ PF07238.14 CRK35725.1 - 0.11 12.9 0.1 1.7 9.0 0.0 3.1 2 1 1 3 3 3 0 PilZ domain PCB_OB PF17092.5 CRK35725.1 - 0.28 12.0 9.8 6.7 7.5 0.0 6.8 6 2 3 9 9 9 0 Penicillin-binding protein OB-like domain FAD_binding_4 PF01565.23 CRK35726.1 - 4.5e-22 78.3 2.8 1.1e-21 77.0 2.8 1.6 1 0 0 1 1 1 1 FAD binding domain Glyco_hydro_43 PF04616.14 CRK35727.1 - 1.8e-26 93.1 0.0 9.3e-15 54.7 0.0 3.2 3 0 0 3 3 3 3 Glycosyl hydrolases family 43 AAR2 PF05282.11 CRK35727.1 - 0.012 15.1 0.2 28 4.0 0.0 3.1 3 0 0 3 3 3 0 AAR2 protein Bac_luciferase PF00296.20 CRK35738.1 - 1e-36 127.0 0.0 1.4e-36 126.5 0.0 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase Haem_degrading PF03928.14 CRK35738.1 - 2.4e-24 85.7 0.0 4e-24 85.0 0.0 1.3 1 0 0 1 1 1 1 Haem-degrading Choline_transpo PF04515.12 CRK35740.1 - 3.8e-23 82.2 28.5 3.8e-23 82.2 28.5 2.9 2 2 1 3 3 3 1 Plasma-membrane choline transporter WW PF00397.26 CRK35742.1 - 1.1e-10 41.4 5.1 2e-10 40.6 5.1 1.5 1 0 0 1 1 1 1 WW domain DUF2012 PF09430.10 CRK35744.1 - 4.7e-22 78.4 0.0 7.3e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) p450 PF00067.22 CRK35746.1 - 6.4e-60 203.2 0.0 8.7e-60 202.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cys_Met_Meta_PP PF01053.20 CRK35747.1 - 4.9e-145 482.9 0.0 5.6e-145 482.7 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 CRK35747.1 - 2.3e-12 46.9 0.4 3.9e-12 46.2 0.4 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 CRK35747.1 - 4.7e-10 39.2 0.0 1.2e-09 37.8 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class I and II Aminotran_5 PF00266.19 CRK35747.1 - 1.2e-09 37.6 0.5 2.6e-09 36.5 0.5 1.5 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 CRK35747.1 - 3.3e-05 23.3 0.0 6.8e-05 22.3 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 CRK35747.1 - 0.015 13.8 0.0 0.023 13.2 0.0 1.2 1 0 0 1 1 1 0 Methionine gamma-lyase Asparaginase_C PF17763.1 CRK35747.1 - 0.034 14.4 0.1 0.1 12.9 0.0 1.8 2 0 0 2 2 2 0 Glutaminase/Asparaginase C-terminal domain SepSecS PF05889.13 CRK35747.1 - 0.04 12.6 0.0 0.06 12.0 0.0 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS DASH_Dad2 PF08654.10 CRK35747.1 - 0.13 12.7 0.0 2.9 8.3 0.0 2.6 2 1 1 3 3 3 0 DASH complex subunit Dad2 MARVEL PF01284.23 CRK35748.1 - 9.1e-15 54.9 14.2 1.1e-14 54.7 14.2 1.0 1 0 0 1 1 1 1 Membrane-associating domain Glyco_transf_21 PF13506.6 CRK35748.1 - 0.03 13.8 0.1 0.043 13.3 0.1 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 21 AMP-binding PF00501.28 CRK35749.1 - 8.5e-73 245.3 0.0 1.1e-72 245.0 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Zn_clus PF00172.18 CRK35750.1 - 0.022 14.9 1.6 0.044 13.9 1.6 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Beta-lactamase PF00144.24 CRK35751.1 - 1.9e-42 145.7 0.0 3e-42 145.0 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase FMO-like PF00743.19 CRK35752.1 - 1.1e-20 73.5 0.6 1e-16 60.5 0.0 2.5 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 CRK35752.1 - 5.7e-13 48.7 0.0 4.8e-11 42.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CRK35752.1 - 1.5e-10 40.7 0.0 6.3e-10 38.7 0.0 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 CRK35752.1 - 1.2e-09 37.8 0.0 3.9e-09 36.2 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CRK35752.1 - 7.5e-08 32.5 0.0 1.7e-06 28.1 0.0 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 CRK35752.1 - 0.0011 19.5 0.1 1.5 9.4 0.0 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CRK35752.1 - 0.011 15.7 1.1 14 5.7 0.0 4.0 4 0 0 4 4 4 0 FAD-NAD(P)-binding DAO PF01266.24 CRK35752.1 - 0.016 14.8 0.1 0.99 8.9 0.0 2.8 2 1 0 2 2 2 0 FAD dependent oxidoreductase Shikimate_DH PF01488.20 CRK35752.1 - 0.017 15.2 0.1 3.5 7.7 0.0 2.6 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 CRK35752.1 - 0.037 12.7 0.2 0.6 8.7 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.24 CRK35752.1 - 0.061 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 CRK35752.1 - 0.15 11.1 0.7 0.46 9.5 0.1 2.0 2 1 0 2 2 2 0 Lycopene cyclase protein ThiF PF00899.21 CRK35752.1 - 0.18 11.1 0.0 14 4.9 0.0 2.9 3 0 0 3 3 3 0 ThiF family WD40 PF00400.32 CRK35753.1 - 0.014 16.2 18.5 2.1 9.4 0.3 6.3 7 0 0 7 7 7 0 WD domain, G-beta repeat DUF3987 PF13148.6 CRK35753.1 - 0.044 12.8 0.3 0.074 12.0 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) CTD_bind PF04818.13 CRK35754.1 - 1.2e-09 38.8 0.0 3e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_1 PF00076.22 CRK35754.1 - 1.8e-07 30.9 0.0 3.4e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Citrate_synt PF00285.21 CRK35755.1 - 1.1e-101 340.5 0.0 1.4e-101 340.1 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Eclosion PF04736.12 CRK35755.1 - 0.055 13.2 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 Eclosion hormone Mito_carr PF00153.27 CRK35756.1 - 9e-28 96.0 4.4 6.6e-13 48.4 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein E1-E2_ATPase PF00122.20 CRK35758.1 - 1.1e-49 168.4 5.1 1.1e-49 168.4 5.1 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 CRK35758.1 - 4.7e-17 63.0 0.6 1.4e-16 61.5 0.1 2.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CRK35758.1 - 1.8e-09 37.1 0.0 4.3e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CRK35758.1 - 0.0024 17.7 0.1 0.0047 16.7 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CRK35758.1 - 0.013 15.6 0.0 0.029 14.5 0.0 1.5 1 0 0 1 1 1 0 Cation transport ATPase (P-type) ABM PF03992.16 CRK35759.1 - 0.00098 19.2 0.1 0.0013 18.8 0.1 1.3 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Spindle_Spc25 PF08234.12 CRK35762.1 - 1.2e-25 89.5 0.0 4e-25 87.8 0.0 2.0 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 DUF3425 PF11905.8 CRK35762.1 - 2.2e-18 66.4 0.8 6.4e-18 64.9 0.8 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) MapZ_EC1 PF18041.1 CRK35762.1 - 0.014 15.6 0.2 0.014 15.6 0.2 2.3 2 0 0 2 2 2 0 MapZ extracellular domain 1 Mito_carr PF00153.27 CRK35763.1 - 6.2e-27 93.4 4.2 1.6e-12 47.2 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein ABM PF03992.16 CRK35764.1 - 0.00093 19.3 0.1 0.0012 18.9 0.1 1.3 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase DUF3425 PF11905.8 CRK35766.1 - 3.3e-18 65.8 0.7 5.8e-18 65.1 0.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 CRK35766.1 - 0.0042 17.1 10.4 0.0095 16.0 7.8 2.3 1 1 1 2 2 2 1 bZIP transcription factor SVIP PF15811.5 CRK35766.1 - 0.046 14.2 6.3 0.043 14.2 4.8 1.8 1 1 0 1 1 1 0 Small VCP/p97-interacting protein T4SS PF07996.11 CRK35766.1 - 0.077 13.4 6.1 0.14 12.6 6.1 1.3 1 0 0 1 1 1 0 Type IV secretion system proteins HSCB_C PF07743.13 CRK35766.1 - 1.1 9.7 4.8 1.6 9.3 4.0 1.6 1 1 0 1 1 1 0 HSCB C-terminal oligomerisation domain M PF02370.16 CRK35766.1 - 1.5 9.7 5.4 14 6.6 1.1 2.7 2 0 0 2 2 2 0 M protein repeat bZIP_2 PF07716.15 CRK35766.1 - 2.1 8.5 11.4 0.56 10.3 5.6 2.3 2 0 0 2 2 2 0 Basic region leucine zipper Spindle_Spc25 PF08234.12 CRK35767.1 - 3.7e-26 91.1 0.1 9.1e-26 89.9 0.1 1.7 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 MAP2_projctn PF08377.10 CRK35767.1 - 0.0073 14.4 1.3 0.0086 14.2 1.3 1.1 1 0 0 1 1 1 1 MAP2/Tau projection domain Tht1 PF04163.12 CRK35767.1 - 0.11 11.2 1.8 0.15 10.8 1.8 1.1 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein Tho2 PF11262.8 CRK35767.1 - 0.16 11.2 9.8 0.24 10.6 9.8 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Atg14 PF10186.9 CRK35767.1 - 1 8.4 10.1 1.8 7.6 10.1 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Striatin PF08232.12 CRK35767.1 - 1.1 9.9 15.7 0.12 12.9 8.5 2.2 1 1 1 2 2 2 0 Striatin family V_ATPase_I PF01496.19 CRK35767.1 - 2 6.2 7.1 2.7 5.8 7.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.6 CRK35767.1 - 2.7 7.3 13.5 3.8 6.8 13.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3450 PF11932.8 CRK35767.1 - 3.4 6.9 17.2 2.7 7.2 15.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) APG6_N PF17675.1 CRK35767.1 - 7.5 7.1 21.7 38 4.8 1.3 2.5 1 1 1 2 2 2 0 Apg6 coiled-coil region GMC_oxred_C PF05199.13 CRK35768.1 - 4.5e-37 127.8 0.0 9.2e-29 100.8 0.0 2.4 2 0 0 2 2 2 2 GMC oxidoreductase GMC_oxred_N PF00732.19 CRK35768.1 - 1.9e-29 103.0 0.0 2.9e-28 99.1 0.0 2.2 1 1 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 CRK35768.1 - 0.00021 20.6 0.0 0.00043 19.6 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CRK35768.1 - 0.0027 16.8 1.5 0.0086 15.2 0.3 2.2 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_3 PF13738.6 CRK35768.1 - 0.0034 16.7 0.0 0.21 10.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Ig_C19orf38 PF17737.1 CRK35768.1 - 0.0058 16.9 0.0 7.8 6.9 0.0 2.8 3 0 0 3 3 3 2 Ig domain in C19orf38 (HIDE1) NAD_binding_8 PF13450.6 CRK35768.1 - 0.01 16.0 0.4 0.03 14.6 0.4 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 CRK35768.1 - 0.031 13.5 0.0 0.049 12.9 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 CRK35768.1 - 0.037 13.1 0.0 0.052 12.6 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.14 CRK35768.1 - 0.052 12.2 0.2 0.077 11.7 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein RGI_lyase PF18370.1 CRK35768.1 - 0.16 12.3 0.0 44 4.5 0.0 2.9 3 0 0 3 3 3 0 Rhamnogalacturonan I lyases beta-sheet domain LIM_bind PF01803.16 CRK35770.1 - 1.2e-30 106.9 0.0 9.4e-30 103.9 0.0 4.0 3 3 1 4 4 4 2 LIM-domain binding protein WBP-1 PF11669.8 CRK35770.1 - 9.2 7.0 8.7 0.38 11.4 0.1 2.9 3 0 0 3 3 3 0 WW domain-binding protein 1 HbrB PF08539.11 CRK35771.1 - 3e-52 177.0 0.0 8.7e-52 175.5 0.0 1.9 2 0 0 2 2 2 1 HbrB-like SPX PF03105.19 CRK35771.1 - 1.5e-37 130.4 0.2 9e-28 98.3 0.0 6.0 5 2 2 7 7 7 2 SPX domain Vps39_1 PF10366.9 CRK35771.1 - 5e-33 113.6 0.0 2.1e-32 111.6 0.0 2.2 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 1 CitMHS PF03600.16 CRK35771.1 - 2.4e-19 69.6 33.1 1.1e-16 60.9 20.4 2.6 3 0 0 3 3 3 2 Citrate transporter Na_sulph_symp PF00939.19 CRK35771.1 - 2.7e-19 69.6 35.1 8.9e-19 67.9 22.5 2.2 2 0 0 2 2 2 2 Sodium:sulfate symporter transmembrane region Vps39_2 PF10367.9 CRK35771.1 - 3.9e-16 59.5 0.4 2.1e-12 47.5 0.1 2.9 1 1 1 2 2 2 2 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 CRK35771.1 - 2.8e-12 46.8 0.0 5.4e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 CNH domain Clathrin PF00637.20 CRK35771.1 - 0.028 14.3 1.6 0.1 12.5 0.0 2.5 2 0 0 2 2 2 0 Region in Clathrin and VPS Pyr_redox_2 PF07992.14 CRK35772.1 - 4e-19 68.9 0.0 9.1e-19 67.8 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CRK35772.1 - 2.2e-13 50.6 0.1 6.8e-12 45.8 0.2 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CRK35772.1 - 0.00058 19.0 0.1 0.0011 18.0 0.0 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 CRK35772.1 - 0.0042 16.4 0.1 0.012 14.9 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CRK35772.1 - 0.019 14.1 0.0 0.031 13.4 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) adh_short PF00106.25 CRK35772.1 - 0.024 14.1 0.2 0.054 12.9 0.2 1.5 1 0 0 1 1 1 0 short chain dehydrogenase TrkA_N PF02254.18 CRK35772.1 - 0.025 14.8 0.1 1.5 9.1 0.1 2.4 2 0 0 2 2 2 0 TrkA-N domain DAO PF01266.24 CRK35772.1 - 0.035 13.7 0.5 0.35 10.4 0.1 2.4 2 1 1 3 3 3 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 CRK35772.1 - 0.039 12.8 0.0 0.5 9.2 0.2 2.1 2 0 0 2 2 2 0 Tryptophan halogenase TMP-TENI PF02581.17 CRK35772.1 - 0.072 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Thiamine monophosphate synthase NAD_binding_7 PF13241.6 CRK35772.1 - 0.11 13.0 0.1 0.35 11.3 0.1 1.9 1 0 0 1 1 1 0 Putative NAD(P)-binding Acetyltransf_8 PF13523.6 CRK35773.1 - 2.7e-46 156.8 3.1 4.1e-46 156.3 3.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 CRK35773.1 - 0.038 14.7 0.3 0.085 13.5 0.3 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain AMP-binding PF00501.28 CRK35774.1 - 9.4e-97 324.3 0.0 1.2e-96 323.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CRK35774.1 - 2.3e-12 47.7 0.1 6.2e-12 46.3 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 CRK35775.1 - 3.1e-75 253.4 0.0 3.7e-74 249.8 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme Condensation PF00668.20 CRK35775.1 - 2.7e-61 207.7 0.0 4.4e-33 114.7 0.0 3.5 3 1 0 3 3 3 3 Condensation domain PP-binding PF00550.25 CRK35775.1 - 1.6e-27 95.6 0.9 3.2e-12 46.6 0.1 3.0 3 0 0 3 3 3 2 Phosphopantetheine attachment site bZIP_1 PF00170.21 CRK35776.1 - 6.3e-05 23.0 9.5 0.00012 22.1 9.2 1.6 1 1 1 2 2 2 1 bZIP transcription factor ABC_tran_Xtn PF12848.7 CRK35776.1 - 0.016 15.3 1.2 0.029 14.4 1.2 1.4 1 0 0 1 1 1 0 ABC transporter DUF3425 PF11905.8 CRK35776.1 - 0.037 14.0 1.7 0.28 11.2 1.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3425) DUF1943 PF09172.11 CRK35776.1 - 0.25 10.5 0.0 0.37 10.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) p450 PF00067.22 CRK35777.1 - 7.9e-71 239.2 0.0 9.2e-71 238.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Acyl-CoA_dh_1 PF00441.24 CRK35778.1 - 8.7e-33 113.7 0.3 1.6e-32 112.8 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 CRK35778.1 - 1.1e-23 83.2 0.0 1.9e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 CRK35778.1 - 1.4e-12 48.3 0.3 1.5e-11 44.9 0.1 2.5 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 CRK35778.1 - 1.7e-05 25.1 0.2 3.2e-05 24.2 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Aldedh PF00171.22 CRK35779.1 - 2.3e-143 478.0 0.2 2.8e-143 477.8 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF917 PF06032.12 CRK35780.1 - 7.2e-20 71.1 0.1 3.5e-14 52.4 0.0 3.6 2 1 1 3 3 3 2 Protein of unknown function (DUF917) Glyco_hydro_3 PF00933.21 CRK35781.1 - 1.1e-40 140.0 0.0 1.8e-40 139.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 CRK35781.1 - 3.7e-10 40.1 0.0 6.1e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Abhydrolase_4 PF08386.10 CRK35782.1 - 3.5e-19 68.8 0.0 7.8e-19 67.7 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 CRK35782.1 - 6.5e-12 45.6 0.0 7.3e-07 29.1 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Serglycin PF04360.12 CRK35783.1 - 0.31 11.0 1.5 0.58 10.1 1.5 1.3 1 0 0 1 1 1 0 Serglycin DUF4050 PF13259.6 CRK35784.1 - 1.7e-61 207.8 0.5 1.7e-61 207.8 0.5 3.0 3 1 0 3 3 3 1 Protein of unknown function (DUF4050) APH PF01636.23 CRK35786.1 - 0.0017 18.3 0.5 0.004 17.1 0.4 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family MYCBPAP PF14646.6 CRK35787.1 - 0.12 11.3 0.1 0.14 11.1 0.1 1.1 1 0 0 1 1 1 0 MYCBP-associated protein family RHH_1 PF01402.21 CRK35787.1 - 0.13 12.2 0.2 7.7 6.6 0.0 2.3 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family NIF3 PF01784.18 CRK35788.1 - 4.4e-62 209.9 0.0 5.7e-62 209.5 0.0 1.1 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) BolA PF01722.18 CRK35789.1 - 1.1e-19 70.4 0.1 2.9e-19 69.1 0.1 1.6 1 1 0 1 1 1 1 BolA-like protein Adaptin_N PF01602.20 CRK35790.1 - 4.4e-138 461.1 4.7 6.1e-138 460.6 4.7 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CRK35790.1 - 1.7e-62 210.3 3.0 2.6e-61 206.4 0.4 2.6 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CRK35790.1 - 5.9e-17 61.8 3.6 1.9e-06 28.2 0.1 6.1 2 1 5 7 7 7 5 HEAT repeats HEAT PF02985.22 CRK35790.1 - 6.2e-11 41.6 6.5 0.016 15.4 0.0 6.3 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.6 CRK35790.1 - 2.2e-05 24.8 1.2 0.29 11.7 0.0 5.3 4 1 1 5 5 4 1 HEAT-like repeat UNC45-central PF11701.8 CRK35790.1 - 0.015 15.2 0.4 0.54 10.2 0.1 2.7 2 0 0 2 2 2 0 Myosin-binding striated muscle assembly central CLASP_N PF12348.8 CRK35790.1 - 0.02 14.5 0.2 2.1 7.9 0.0 3.4 2 1 1 3 3 3 0 CLASP N terminal RTP1_C1 PF10363.9 CRK35790.1 - 0.024 14.8 1.1 1.7 8.9 0.0 4.0 2 2 2 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 CRK35790.1 - 0.046 13.8 2.1 18 5.6 0.1 4.9 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 CRK35790.1 - 0.081 13.0 0.0 11 6.2 0.0 3.4 2 1 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain RIX1 PF08167.12 CRK35790.1 - 0.11 12.2 0.2 28 4.4 0.1 2.9 2 1 0 2 2 2 0 rRNA processing/ribosome biogenesis DNA_ligase_A_M PF01068.21 CRK35792.1 - 1.1e-48 165.6 0.2 3.4e-46 157.5 0.0 2.2 2 0 0 2 2 2 2 ATP dependent DNA ligase domain PDCD2_C PF04194.13 CRK35792.1 - 1e-25 90.8 0.0 3.8e-24 85.7 0.0 2.7 2 1 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain DNA_ligase_A_N PF04675.14 CRK35792.1 - 3.7e-18 66.4 0.0 1e-17 65.0 0.0 1.7 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 CRK35792.1 - 4.7e-12 46.4 0.0 2.3e-11 44.1 0.0 2.3 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 CRK35792.1 - 0.00088 19.6 0.0 0.0022 18.3 0.0 1.7 2 0 0 2 2 2 1 RNA ligase Cpn60_TCP1 PF00118.24 CRK35793.1 - 6.6e-161 536.3 0.3 7.4e-161 536.1 0.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Herpes_UL6 PF01763.16 CRK35793.1 - 0.12 10.9 0.0 0.17 10.3 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like VID27 PF08553.10 CRK35794.1 - 2e-190 632.4 0.0 2.6e-190 632.0 0.0 1.1 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 CRK35794.1 - 1.8e-76 255.8 0.7 1.8e-76 255.8 0.7 3.0 2 1 1 3 3 3 1 VID27 N-terminal region VID27_PH PF17747.1 CRK35794.1 - 9.4e-45 151.4 0.9 3.7e-44 149.5 0.3 2.1 2 0 0 2 2 2 1 VID27 PH-like domain CDC45 PF02724.14 CRK35794.1 - 4.2 5.5 7.1 6.2 5.0 7.1 1.2 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 CRK35794.1 - 4.3 5.3 13.5 7 4.6 13.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi Glyco_transf_20 PF00982.21 CRK35795.1 - 6.4e-197 654.9 0.0 7.3e-197 654.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.11 CRK35795.1 - 0.042 13.6 0.2 0.14 11.8 0.1 1.9 2 0 0 2 2 2 0 Starch synthase catalytic domain Collagen PF01391.18 CRK35797.1 - 0.0014 18.3 37.9 0.0014 18.3 37.9 2.9 3 0 0 3 3 3 2 Collagen triple helix repeat (20 copies) Aldose_epim PF01263.20 CRK35798.1 - 2.3e-53 181.5 0.0 2.9e-53 181.1 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase DUF3767 PF12597.8 CRK35800.1 - 1.2e-32 111.8 0.0 1.2e-32 111.8 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3767) BEX PF04538.12 CRK35800.1 - 0.011 16.4 2.4 0.011 16.4 2.4 1.6 2 0 0 2 2 2 0 Brain expressed X-linked like family PALP PF00291.25 CRK35800.1 - 0.023 14.1 0.1 0.031 13.7 0.1 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme CCB1 PF12046.8 CRK35800.1 - 0.16 11.3 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Cofactor assembly of complex C subunit B TrbI_Ftype PF09677.10 CRK35800.1 - 0.19 12.0 0.7 0.31 11.4 0.7 1.3 1 0 0 1 1 1 0 Type-F conjugative transfer system protein (TrbI_Ftype) DUF1744 PF08490.12 CRK35801.1 - 1.2e-154 514.8 0.0 1.7e-154 514.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 CRK35801.1 - 2.3e-95 319.6 0.3 1.7e-46 158.9 0.2 2.4 1 1 1 2 2 2 2 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 CRK35801.1 - 1.5e-15 56.9 0.0 7e-13 48.1 0.1 2.9 3 1 0 3 3 3 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 CRK35801.1 - 4.1e-10 39.7 0.3 1.2e-09 38.2 0.3 1.7 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 CRK35801.1 - 9.1e-06 25.8 0.0 3.2e-05 24.0 0.0 2.0 1 0 0 1 1 1 1 RNase_H superfamily HET PF06985.11 CRK35802.1 - 1.5e-26 93.5 2.1 5.3e-26 91.7 2.1 2.0 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Cpn60_TCP1 PF00118.24 CRK35803.1 - 3.4e-153 510.8 6.4 4e-153 510.6 6.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pyr_redox_2 PF07992.14 CRK35803.1 - 0.031 13.5 0.8 0.31 10.2 0.8 2.3 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PNTB_4TM PF12769.7 CRK35803.1 - 0.069 13.6 0.1 0.27 11.7 0.0 2.0 2 0 0 2 2 2 0 4TM region of pyridine nucleotide transhydrogenase, mitoch Orn_Arg_deC_N PF02784.16 CRK35805.1 - 1e-75 254.3 0.0 1.3e-75 254.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Ribosomal_S7 PF00177.21 CRK35807.1 - 0.00077 19.1 0.0 0.001 18.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Peptidase_M1_N PF17900.1 CRK35808.1 - 0.021 15.0 0.1 0.024 14.8 0.1 1.1 1 0 0 1 1 1 0 Peptidase M1 N-terminal domain WD40 PF00400.32 CRK35809.1 - 2.3e-05 25.1 1.9 0.15 12.9 0.3 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat Enoyl_reductase PF12241.8 CRK35809.1 - 0.015 14.6 0.0 0.016 14.5 0.0 1.1 1 0 0 1 1 1 0 Trans-2-enoyl-CoA reductase catalytic region Unstab_antitox PF09720.10 CRK35809.1 - 0.021 14.9 0.0 0.034 14.2 0.0 1.4 1 0 0 1 1 1 0 Putative addiction module component STE PF02200.16 CRK35809.1 - 0.025 15.0 0.0 0.025 15.0 0.0 1.1 1 0 0 1 1 1 0 STE like transcription factor Fer4_8 PF13183.6 CRK35810.1 - 4.8e-10 39.7 4.5 8.4e-10 39.0 4.5 1.3 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 CRK35810.1 - 8.9e-10 39.0 5.8 1.1e-09 38.6 5.8 1.1 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 CRK35810.1 - 5.6e-09 36.0 2.9 7.4e-09 35.6 2.9 1.1 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 CRK35810.1 - 1.6e-05 25.4 3.4 3.1e-05 24.5 3.4 1.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 CRK35810.1 - 0.0078 16.4 8.1 0.029 14.5 8.1 1.8 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_4 PF12800.7 CRK35810.1 - 0.023 15.2 6.4 0.54 10.9 1.2 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_18 PF13746.6 CRK35810.1 - 0.039 14.2 1.4 1.9 8.7 0.7 2.1 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 CRK35810.1 - 0.5 11.4 14.7 2.3 9.3 0.5 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4 PF00037.27 CRK35810.1 - 1.5 8.8 12.1 10 6.1 0.3 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_2 PF12797.7 CRK35810.1 - 7.3 6.9 14.8 15 5.9 1.1 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain PIP5K PF01504.18 CRK35811.1 - 1.5e-100 336.0 0.2 1.5e-100 336.0 0.2 1.6 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase UQ_con PF00179.26 CRK35811.1 - 1.4e-23 83.1 0.0 2.8e-23 82.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme NAD_binding_6 PF08030.12 CRK35811.1 - 1.5e-16 60.9 0.0 3.3e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain DUF601 PF04642.12 CRK35811.1 - 0.11 11.9 3.3 0.19 11.2 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF601 Neur_chan_memb PF02932.16 CRK35811.1 - 3.3 7.7 5.7 6.8 6.7 5.7 1.6 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3446 PF11928.8 CRK35812.1 - 5.8 7.3 7.1 32 4.9 7.1 2.0 1 1 0 1 1 1 0 Early growth response N-terminal domain DPBB_1 PF03330.18 CRK35814.1 - 0.00017 21.8 0.0 0.00032 20.9 0.0 1.4 1 0 0 1 1 1 1 Lytic transglycolase Ndc1_Nup PF09531.10 CRK35814.1 - 2.1 6.9 4.8 2.2 6.9 4.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Yippee-Mis18 PF03226.14 CRK35816.1 - 1e-07 32.1 0.1 1e-07 32.1 0.1 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Hexokinase_1 PF00349.21 CRK35817.1 - 8.4e-22 78.0 0.1 9.4e-22 77.9 0.1 1.0 1 0 0 1 1 1 1 Hexokinase MRC1 PF09444.10 CRK35820.1 - 0.012 16.1 3.9 0.016 15.7 3.9 1.1 1 0 0 1 1 1 0 MRC1-like domain Spem1 PF15670.5 CRK35820.1 - 0.52 9.8 3.9 0.62 9.6 3.9 1.0 1 0 0 1 1 1 0 Spermatid maturation protein 1 AIM3 PF17096.5 CRK35820.1 - 4.1 8.4 10.8 5.2 8.1 10.3 1.6 1 1 0 1 1 1 0 Altered inheritance of mitochondria protein 3 SNF2_N PF00176.23 CRK35822.1 - 1.6e-07 30.4 0.2 4.7e-07 28.9 0.2 1.6 1 1 1 2 2 2 1 SNF2 family N-terminal domain AChE_tetra PF08674.10 CRK35823.1 - 0.068 12.9 1.3 0.081 12.6 0.7 1.4 1 1 0 1 1 1 0 Acetylcholinesterase tetramerisation domain Arginase PF00491.21 CRK35824.1 - 1.8e-41 142.5 0.0 2e-41 142.3 0.0 1.0 1 0 0 1 1 1 1 Arginase family HEAT PF02985.22 CRK35826.1 - 0.0069 16.6 0.0 5.2 7.6 0.0 2.6 2 0 0 2 2 2 2 HEAT repeat RNA_pol_Rpb5_C PF01191.19 CRK35832.1 - 1e-28 99.0 0.2 1.3e-28 98.7 0.2 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain PA PF02225.22 CRK35836.1 - 7.4e-11 41.9 0.0 8.9e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 PA domain UBD PF16455.5 CRK35837.1 - 9.4e-24 83.7 0.2 1.1e-23 83.4 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-binding domain LCCL PF03815.19 CRK35838.1 - 0.47 10.6 3.3 0.55 10.4 3.3 1.1 1 0 0 1 1 1 0 LCCL domain PQ-loop PF04193.14 CRK35839.1 - 5.1e-38 128.6 13.8 2.6e-19 68.7 0.1 3.6 3 1 1 4 4 4 2 PQ loop repeat DUF4190 PF13828.6 CRK35839.1 - 0.017 14.9 0.2 0.24 11.2 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) ER_lumen_recept PF00810.18 CRK35839.1 - 0.032 15.1 2.3 0.85 10.4 0.1 2.9 2 1 1 3 3 3 0 ER lumen protein retaining receptor TraT PF05818.12 CRK35839.1 - 0.15 11.7 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein S1-P1_nuclease PF02265.16 CRK35840.1 - 3.7e-71 239.9 0.1 4.2e-71 239.7 0.1 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease DUF1152 PF06626.12 CRK35842.1 - 0.014 14.6 0.1 0.021 14.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1152) TPR_2 PF07719.17 CRK35844.1 - 1.2e-10 40.6 0.1 4.7e-06 26.3 0.0 2.5 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 CRK35844.1 - 2.3e-08 33.5 1.3 0.0037 17.0 0.1 3.3 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 CRK35844.1 - 3.5e-08 33.9 0.1 0.00076 19.9 0.6 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 CRK35844.1 - 8.2e-08 32.4 0.0 0.0061 16.8 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 CRK35844.1 - 9.8e-08 31.6 0.3 0.03 14.5 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 CRK35844.1 - 1.5e-07 31.3 0.0 6.3e-06 26.2 0.0 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 CRK35844.1 - 2.8e-06 27.9 0.0 0.0011 19.6 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 CRK35844.1 - 1.2e-05 24.9 0.1 0.029 14.4 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 CRK35844.1 - 1.9e-05 24.4 0.0 0.032 14.1 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 CRK35844.1 - 0.00017 22.1 0.0 0.13 13.2 0.0 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 CRK35844.1 - 0.0018 18.8 0.1 6.4 7.6 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CRK35844.1 - 0.0022 18.2 0.7 0.82 9.9 0.3 2.1 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.9 CRK35844.1 - 0.0027 17.1 0.1 0.0057 16.1 0.0 1.6 2 0 0 2 2 2 1 SHNi-TPR TPR_MalT PF17874.1 CRK35844.1 - 0.01 15.2 0.0 0.011 15.1 0.0 1.1 1 0 0 1 1 1 0 MalT-like TPR region TPR_11 PF13414.6 CRK35844.1 - 0.012 15.3 0.1 0.03 14.0 0.0 1.8 2 0 0 2 2 2 0 TPR repeat TPR_3 PF07720.12 CRK35844.1 - 0.013 15.5 3.1 1.4 9.0 0.4 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF410 PF04190.13 CRK35845.1 - 8.1e-25 88.1 0.0 9.4e-25 87.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF410) DUF3368 PF11848.8 CRK35845.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3368) SET PF00856.28 CRK35847.1 - 8.9e-19 68.5 1.0 6.4e-18 65.7 0.2 2.4 2 1 0 2 2 2 1 SET domain VIT1 PF01988.19 CRK35847.1 - 0.077 12.8 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 VIT family DHDPS PF00701.22 CRK35848.1 - 8.5e-05 21.4 0.0 9.2e-05 21.3 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Biotin_lipoyl PF00364.22 CRK35849.1 - 1.9e-21 75.7 1.2 3e-21 75.0 0.6 1.6 1 1 1 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 CRK35849.1 - 1.4e-05 24.8 0.0 4.3e-05 23.2 0.0 1.7 1 1 0 1 1 1 1 Biotin-lipoyl like HlyD_3 PF13437.6 CRK35849.1 - 0.00091 19.9 0.3 0.044 14.5 0.0 2.0 1 1 1 2 2 2 1 HlyD family secretion protein QRPTase_N PF02749.16 CRK35849.1 - 0.018 15.1 0.1 0.11 12.6 0.0 2.0 1 1 1 2 2 2 0 Quinolinate phosphoribosyl transferase, N-terminal domain HlyD_D23 PF16576.5 CRK35849.1 - 0.074 12.3 0.1 4.2 6.5 0.0 2.0 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion YqfD PF06898.11 CRK35849.1 - 0.081 11.7 0.5 0.33 9.7 0.5 1.7 1 1 1 2 2 2 0 Putative stage IV sporulation protein YqfD T2SSB PF16537.5 CRK35849.1 - 0.13 11.9 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Type II secretion system protein B Mpv17_PMP22 PF04117.12 CRK35850.1 - 6e-11 42.4 3.3 8e-11 42.0 3.3 1.2 1 0 0 1 1 1 1 Mpv17 / PMP22 family DDDD PF10161.9 CRK35851.1 - 0.16 11.8 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 Putative mitochondrial precursor protein Rad52_Rad22 PF04098.15 CRK35852.1 - 0.069 13.1 0.0 0.078 12.9 0.0 1.1 1 0 0 1 1 1 0 Rad52/22 family double-strand break repair protein PRK PF00485.18 CRK35853.1 - 3.5e-08 33.4 0.0 7.4e-08 32.4 0.0 1.5 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family MeaB PF03308.16 CRK35853.1 - 4.3e-05 22.6 0.0 8.1e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 CRK35853.1 - 4.5e-05 23.9 0.0 6.4e-05 23.4 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 CRK35853.1 - 0.00011 22.8 0.0 0.00027 21.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 CRK35853.1 - 0.00012 21.5 0.0 0.00022 20.6 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.6 CRK35853.1 - 0.00023 21.4 0.0 0.0011 19.2 0.0 2.4 1 1 0 1 1 1 1 AAA domain APS_kinase PF01583.20 CRK35853.1 - 0.0012 18.7 0.0 0.0022 17.9 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_17 PF13207.6 CRK35853.1 - 0.0061 17.0 0.0 0.019 15.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CRK35853.1 - 0.0082 16.4 0.1 0.029 14.6 0.0 1.8 2 1 0 2 2 2 1 AAA domain Torsin PF06309.11 CRK35853.1 - 0.0087 16.2 0.0 0.014 15.5 0.0 1.3 1 0 0 1 1 1 1 Torsin NB-ARC PF00931.22 CRK35853.1 - 0.009 15.2 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain KTI12 PF08433.10 CRK35853.1 - 0.0094 15.4 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Viral_helicase1 PF01443.18 CRK35853.1 - 0.011 15.5 0.0 0.025 14.3 0.0 1.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase T2SSE PF00437.20 CRK35853.1 - 0.015 14.4 0.0 0.034 13.2 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein Thymidylate_kin PF02223.17 CRK35853.1 - 0.028 14.1 0.0 0.056 13.1 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase Ploopntkinase3 PF18751.1 CRK35853.1 - 0.031 14.2 0.0 0.064 13.2 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA PF00004.29 CRK35853.1 - 0.036 14.5 0.0 0.065 13.7 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 CRK35853.1 - 0.059 13.3 0.0 0.092 12.7 0.0 1.3 1 0 0 1 1 1 0 NACHT domain DUF815 PF05673.13 CRK35853.1 - 0.083 12.0 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_30 PF13604.6 CRK35853.1 - 0.087 12.5 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 CRK35853.1 - 0.088 12.4 0.0 0.23 11.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 CRK35853.1 - 0.098 11.9 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) CbiA PF01656.23 CRK35853.1 - 0.1 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain TrwB_AAD_bind PF10412.9 CRK35853.1 - 0.12 11.3 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain NTPase_1 PF03266.15 CRK35853.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 NTPase AAA_28 PF13521.6 CRK35853.1 - 0.14 12.4 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CRK35853.1 - 0.22 11.9 0.0 0.37 11.2 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Sugar_tr PF00083.24 CRK35854.1 - 3.3e-105 352.6 11.2 5.9e-105 351.7 11.2 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK35854.1 - 4.5e-22 78.5 41.0 3.5e-11 42.6 17.6 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily Cir_N PF10197.9 CRK35855.1 - 8.3e-09 35.5 2.2 8.3e-09 35.5 2.2 4.7 4 1 0 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR AAA PF00004.29 CRK35856.1 - 3e-48 163.6 0.0 6.2e-38 130.2 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CRK35856.1 - 5.5e-09 35.7 0.2 1.2e-08 34.6 0.2 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 CRK35856.1 - 3e-07 30.8 0.0 0.00017 21.9 0.0 3.4 2 2 0 2 2 2 1 AAA domain TIP49 PF06068.13 CRK35856.1 - 7.9e-07 28.6 0.0 0.018 14.3 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_16 PF13191.6 CRK35856.1 - 2.6e-06 27.9 0.0 0.076 13.4 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_2 PF07724.14 CRK35856.1 - 3.2e-06 27.4 0.4 0.00012 22.3 0.1 3.0 2 1 1 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 CRK35856.1 - 6e-05 23.6 0.0 0.013 16.0 0.0 2.9 3 0 0 3 3 3 1 AAA domain Mg_chelatase PF01078.21 CRK35856.1 - 9.1e-05 21.9 0.3 0.0099 15.3 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI CDC48_2 PF02933.17 CRK35856.1 - 0.00014 21.5 0.2 0.0012 18.6 0.0 2.6 2 1 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_5 PF07728.14 CRK35856.1 - 0.00015 21.8 0.0 0.0025 17.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 CRK35856.1 - 0.00016 21.3 0.3 0.048 13.2 0.0 2.8 3 0 0 3 3 2 1 P-loop containing dynein motor region Parvo_NS1 PF01057.17 CRK35856.1 - 0.00017 20.8 0.0 0.19 10.8 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_14 PF13173.6 CRK35856.1 - 0.00028 20.9 0.0 0.54 10.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 CRK35856.1 - 0.00031 21.1 0.0 0.29 11.5 0.0 2.6 2 0 0 2 2 2 1 RNA helicase ATPase_2 PF01637.18 CRK35856.1 - 0.00041 20.3 0.0 13 5.7 0.0 4.1 2 2 1 4 4 4 0 ATPase domain predominantly from Archaea RuvB_N PF05496.12 CRK35856.1 - 0.00087 19.1 0.1 0.1 12.4 0.0 2.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 CRK35856.1 - 0.0017 18.5 0.0 0.28 11.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 CRK35856.1 - 0.0019 17.9 0.0 0.078 12.7 0.0 2.6 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 CRK35856.1 - 0.0024 17.6 0.0 0.069 12.9 0.0 2.9 3 0 0 3 3 3 1 IstB-like ATP binding protein NB-ARC PF00931.22 CRK35856.1 - 0.0036 16.5 0.1 2.7 7.1 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain TsaE PF02367.17 CRK35856.1 - 0.0045 17.0 0.0 0.42 10.6 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 CRK35856.1 - 0.0075 15.6 1.6 0.18 11.1 0.2 2.5 3 0 0 3 3 2 1 KaiC PhoH PF02562.16 CRK35856.1 - 0.012 15.1 0.0 1.4 8.3 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein Sigma54_activat PF00158.26 CRK35856.1 - 0.012 15.3 0.0 1.4 8.6 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Vps4_C PF09336.10 CRK35856.1 - 0.024 14.6 0.1 0.086 12.9 0.0 1.9 2 0 0 2 2 1 0 Vps4 C terminal oligomerisation domain TniB PF05621.11 CRK35856.1 - 0.033 13.6 0.1 5.3 6.4 0.1 3.3 3 1 0 3 3 2 0 Bacterial TniB protein AAA_25 PF13481.6 CRK35856.1 - 0.036 13.6 0.1 3.4 7.2 0.0 2.9 3 1 1 4 4 3 0 AAA domain ABC_tran PF00005.27 CRK35856.1 - 0.078 13.5 0.1 0.55 10.7 0.1 2.3 3 0 0 3 3 2 0 ABC transporter NACHT PF05729.12 CRK35856.1 - 0.079 12.9 0.8 28 4.6 0.0 3.4 3 1 0 3 3 2 0 NACHT domain AAA_19 PF13245.6 CRK35856.1 - 0.11 12.8 0.1 1.3 9.4 0.1 2.5 3 0 0 3 3 3 0 AAA domain Band_7 PF01145.25 CRK35857.1 - 6.7e-07 29.5 0.1 7.4e-07 29.3 0.1 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family PCRF PF03462.18 CRK35861.1 - 5.8e-23 81.8 0.0 3.6e-21 75.9 0.0 2.0 1 1 0 1 1 1 1 PCRF domain PALP PF00291.25 CRK35862.1 - 1.5e-50 172.3 1.8 2.8e-50 171.4 1.8 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Peptidase_M20 PF01546.28 CRK35862.1 - 1e-22 80.8 0.0 7.9e-22 78.0 0.0 2.3 2 1 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CRK35862.1 - 7.6e-15 54.8 0.0 2e-14 53.4 0.0 1.8 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 CRK35862.1 - 0.02 14.6 0.2 0.1 12.3 0.1 2.1 3 0 0 3 3 3 0 Peptidase family M28 SRR1 PF07985.12 CRK35863.1 - 3.9e-05 23.6 0.0 9.3e-05 22.4 0.0 1.7 1 1 0 1 1 1 1 SRR1 Trehalose_PPase PF02358.16 CRK35865.1 - 7.8e-16 57.9 0.0 9.5e-16 57.6 0.0 1.0 1 0 0 1 1 1 1 Trehalose-phosphatase TPR_8 PF13181.6 CRK35868.1 - 0.011 15.9 0.1 0.026 14.7 0.1 1.7 1 1 0 1 1 1 0 Tetratricopeptide repeat Spore_III_AB PF09548.10 CRK35868.1 - 0.023 14.8 0.2 0.025 14.7 0.2 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) TPR_2 PF07719.17 CRK35868.1 - 0.024 14.7 0.2 0.048 13.8 0.2 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Daxx PF03344.15 CRK35868.1 - 0.11 12.5 0.0 0.14 12.3 0.0 1.1 1 0 0 1 1 1 0 Daxx N-terminal Rassf1C-interacting domain TPR_14 PF13428.6 CRK35868.1 - 0.12 13.2 1.5 0.15 12.9 0.4 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Glycos_transf_2 PF00535.26 CRK35869.1 - 5.6e-09 36.0 0.0 6.4e-09 35.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 CRK35869.1 - 0.0033 16.9 0.0 0.0041 16.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 21 NTP_transferase PF00483.23 CRK35870.1 - 3.8e-32 111.8 0.0 8.8e-32 110.6 0.0 1.6 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.24 CRK35870.1 - 1.1e-17 63.0 17.1 3.3e-10 39.3 1.7 3.5 2 2 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 CRK35870.1 - 4.7e-08 32.7 2.4 2.9e-06 26.9 1.0 3.0 2 1 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 CRK35870.1 - 0.00015 20.0 0.2 0.00023 19.5 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) EXS PF03124.14 CRK35875.1 - 2.1e-84 283.7 13.8 7.5e-55 186.5 1.4 2.1 2 0 0 2 2 2 2 EXS family Rad21_Rec8_N PF04825.13 CRK35875.1 - 7.7e-37 125.8 0.0 1.5e-36 124.9 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein EURL PF06937.11 CRK35875.1 - 0.069 12.6 0.1 0.12 11.8 0.1 1.2 1 0 0 1 1 1 0 EURL protein Ank_4 PF13637.6 CRK35879.1 - 7.1e-15 55.2 0.4 1.2e-09 38.5 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 CRK35879.1 - 3.8e-14 52.5 1.0 8.2e-12 45.1 0.3 1.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 CRK35879.1 - 2.4e-10 40.4 1.1 9.8e-05 22.6 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 CRK35879.1 - 6.4e-10 39.5 0.0 9.5e-10 38.9 0.0 1.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CRK35879.1 - 1.7e-08 34.0 0.1 0.0015 18.8 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat JAB PF01398.21 CRK35880.1 - 0.00026 21.0 0.0 0.00032 20.6 0.0 1.1 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF4682 PF15733.5 CRK35883.1 - 0.021 15.4 4.1 1.4 9.5 0.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4682) EpmC PF04315.12 CRK35883.1 - 0.11 12.1 0.2 5.1 6.8 0.0 2.3 2 0 0 2 2 2 0 Elongation factor P hydroxylase Utp12 PF04003.12 CRK35885.1 - 3.8e-22 78.6 0.1 8e-22 77.6 0.1 1.6 1 0 0 1 1 1 1 Dip2/Utp12 Family SDA1 PF05285.12 CRK35885.1 - 0.049 13.1 29.4 0.22 10.9 3.0 2.2 2 0 0 2 2 2 0 SDA1 Nop14 PF04147.12 CRK35885.1 - 0.18 10.0 26.8 0.73 8.0 18.9 2.1 2 0 0 2 2 2 0 Nop14-like family BUD22 PF09073.10 CRK35885.1 - 8.3 5.6 34.9 2.8 7.2 9.2 2.1 2 0 0 2 2 2 0 BUD22 Bromodomain PF00439.25 CRK35887.1 - 5.5e-33 112.9 0.0 2.6e-18 65.9 0.0 2.5 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 CRK35887.1 - 1.3e-12 47.7 1.3 1.3e-12 47.7 1.3 2.0 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation DUF2555 PF10742.9 CRK35887.1 - 0.069 13.0 0.5 0.19 11.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2555) CMD PF02627.20 CRK35889.1 - 0.089 12.9 0.8 0.21 11.7 0.8 1.6 1 0 0 1 1 1 0 Carboxymuconolactone decarboxylase family HEAT PF02985.22 CRK35889.1 - 0.17 12.3 0.0 0.49 10.8 0.0 1.8 1 0 0 1 1 1 0 HEAT repeat ECH_1 PF00378.20 CRK35891.1 - 9e-30 103.8 0.0 1.2e-29 103.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CRK35891.1 - 5.9e-07 29.3 0.0 1.3e-06 28.1 0.0 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase adh_short PF00106.25 CRK35893.1 - 0.00013 21.5 0.0 0.00019 20.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK35893.1 - 0.0077 15.8 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 CRK35893.1 - 0.008 15.7 0.0 0.0099 15.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CRK35893.1 - 0.0093 15.4 0.2 0.018 14.4 0.2 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase DUF1992 PF09350.10 CRK35898.1 - 1.7e-18 66.5 0.6 2.4e-13 50.0 0.1 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF1992) TRCF PF03461.15 CRK35898.1 - 0.19 12.1 0.2 8 6.9 0.0 2.7 3 0 0 3 3 3 0 TRCF domain MFS_1 PF07690.16 CRK35901.1 - 5.1e-22 78.3 30.1 5.1e-22 78.3 30.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 CRK35901.1 - 2.4e-10 40.3 6.6 2.4e-10 40.3 6.6 2.7 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1_like PF12832.7 CRK35901.1 - 0.0012 17.8 5.7 0.0012 17.8 5.7 2.0 1 1 1 2 2 2 1 MFS_1 like family DUF981 PF06168.11 CRK35901.1 - 0.017 15.1 0.9 0.017 15.1 0.9 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF981) RasGEF PF00617.19 CRK35903.1 - 4e-51 173.7 0.0 8.5e-51 172.7 0.0 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 CRK35903.1 - 5.2e-16 58.8 0.0 2.3e-15 56.7 0.0 2.1 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_9 PF14604.6 CRK35903.1 - 2.1e-06 27.5 0.0 5.2e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CRK35903.1 - 6.5e-05 22.4 0.0 0.00014 21.4 0.0 1.6 1 0 0 1 1 1 1 SH3 domain Exo_endo_phos PF03372.23 CRK35904.1 - 6.4e-06 25.9 1.3 1.4e-05 24.7 1.3 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Jacalin PF01419.17 CRK35904.1 - 0.00064 19.7 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 Jacalin-like lectin domain DUF2183 PF09949.9 CRK35909.1 - 1.4e-32 112.0 0.1 1.1e-31 109.0 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) SOR_SNZ PF01680.17 CRK35912.1 - 0.17 11.6 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 SOR/SNZ family Asp PF00026.23 CRK35914.1 - 1.2e-10 41.3 0.0 2.2e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic aspartyl protease adh_short_C2 PF13561.6 CRK35915.1 - 6e-49 166.7 0.3 8.3e-49 166.3 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRK35915.1 - 1.2e-39 135.8 0.1 1.6e-39 135.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CRK35915.1 - 3.4e-11 43.4 0.6 5.8e-11 42.6 0.6 1.3 1 0 0 1 1 1 1 KR domain FANCA_interact PF15751.5 CRK35915.1 - 0.073 13.6 0.1 0.18 12.3 0.1 1.6 1 0 0 1 1 1 0 FAAP20 FANCA interaction domain ABC_tran PF00005.27 CRK35916.1 - 2.5e-44 151.1 0.0 1.9e-26 93.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 CRK35916.1 - 2.6e-35 122.4 18.7 2.3e-16 60.3 0.6 3.5 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.19 CRK35916.1 - 7.9e-12 45.1 0.3 0.00023 20.7 0.0 4.1 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CRK35916.1 - 2.8e-06 28.0 0.3 0.00081 19.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CRK35916.1 - 5e-06 26.1 1.4 0.026 14.3 0.4 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 CRK35916.1 - 2.2e-05 24.8 0.1 0.34 11.2 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_21 PF13304.6 CRK35916.1 - 5.3e-05 23.2 2.7 0.099 12.4 0.2 3.8 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 CRK35916.1 - 0.00037 20.9 0.5 0.8 10.1 0.0 3.0 3 0 0 3 3 2 2 AAA ATPase domain DUF87 PF01935.17 CRK35916.1 - 0.0006 20.0 0.6 0.0062 16.7 0.3 2.2 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_25 PF13481.6 CRK35916.1 - 0.001 18.7 0.6 0.031 13.8 0.3 2.7 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 CRK35916.1 - 0.0012 18.0 0.1 1.2 8.1 0.4 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein RsgA_GTPase PF03193.16 CRK35916.1 - 0.0026 17.7 0.0 2.4 8.0 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase cobW PF02492.19 CRK35916.1 - 0.0035 16.9 0.1 0.94 9.0 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.18 CRK35916.1 - 0.0041 16.5 0.1 0.48 9.7 0.1 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family NACHT PF05729.12 CRK35916.1 - 0.016 15.1 1.7 4 7.3 0.1 2.8 2 0 0 2 2 2 0 NACHT domain MMR_HSR1 PF01926.23 CRK35916.1 - 0.027 14.5 0.0 2 8.5 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase Dynamin_N PF00350.23 CRK35916.1 - 0.037 14.1 0.2 3.7 7.6 0.1 2.4 2 0 0 2 2 2 0 Dynamin family AAA_19 PF13245.6 CRK35916.1 - 0.038 14.3 0.2 9.3 6.6 0.0 3.4 3 0 0 3 3 3 0 AAA domain SbcCD_C PF13558.6 CRK35916.1 - 0.047 13.9 0.0 2.1 8.7 0.0 3.0 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.12 CRK35916.1 - 0.052 12.8 0.1 7 5.9 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin NB-ARC PF00931.22 CRK35916.1 - 0.069 12.3 0.3 7.7 5.6 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain ATP-synt_ab PF00006.25 CRK35916.1 - 0.077 12.6 0.0 3.2 7.4 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_18 PF13238.6 CRK35916.1 - 0.11 13.0 0.0 32 5.1 0.0 3.3 3 0 0 3 3 3 0 AAA domain Spc7 PF08317.11 CRK35916.1 - 0.13 11.1 0.6 0.21 10.4 0.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF2075 PF09848.9 CRK35916.1 - 0.14 11.4 0.7 9.2 5.4 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 CRK35916.1 - 0.14 11.6 0.3 17 4.9 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region TrwB_AAD_bind PF10412.9 CRK35916.1 - 0.15 10.9 0.3 5.2 5.9 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA PF00004.29 CRK35916.1 - 0.17 12.3 0.1 17 5.9 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 CRK35916.1 - 0.21 11.3 1.3 2.9 7.6 0.0 3.2 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_30 PF13604.6 CRK35916.1 - 0.76 9.5 3.8 46 3.7 2.0 3.0 2 1 0 2 2 2 0 AAA domain Zip PF02535.22 CRK35917.1 - 8.9e-48 163.2 2.8 1.2e-47 162.7 2.8 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter Cnn_1N PF07989.11 CRK35918.1 - 6.5e-09 35.8 10.5 6.5e-09 35.8 10.5 2.8 3 0 0 3 3 3 1 Centrosomin N-terminal motif 1 Zn_clus PF00172.18 CRK35918.1 - 9e-05 22.5 1.7 0.00027 21.0 1.7 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 CRK35918.1 - 0.0016 17.6 0.0 0.0029 16.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain SKA1 PF07160.12 CRK35918.1 - 0.029 14.2 3.1 0.084 12.7 3.1 1.8 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 UPF0242 PF06785.11 CRK35918.1 - 1.3 9.1 7.0 4.2 7.4 7.0 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus bZIP_1 PF00170.21 CRK35918.1 - 2.4 8.3 14.6 7.6 6.7 7.6 3.6 2 1 1 3 3 3 0 bZIP transcription factor Fungal_trans PF04082.18 CRK35922.1 - 6e-08 32.0 1.5 1e-06 28.0 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK35922.1 - 1.6e-06 28.1 11.3 2.7e-06 27.4 11.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FdsD PF11390.8 CRK35922.1 - 0.21 11.9 0.3 40 4.6 0.0 2.6 2 0 0 2 2 2 0 NADH-dependant formate dehydrogenase delta subunit FdsD PRKCSH PF07915.13 CRK35923.1 - 8.4e-18 65.2 0.0 2.2e-17 63.8 0.0 1.7 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 CRK35923.1 - 0.026 14.2 0.0 2.8 7.6 0.0 2.4 2 0 0 2 2 2 0 Glucosidase II beta subunit-like protein Acetyltransf_1 PF00583.25 CRK35924.1 - 2.5e-11 43.8 0.0 3.4e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CRK35924.1 - 1.5e-07 31.7 0.0 2.9e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CRK35924.1 - 6.9e-06 26.0 0.0 2.9e-05 24.0 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Glyoxalase PF00903.25 CRK35924.1 - 0.0013 18.9 0.0 0.0023 18.1 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FR47 PF08445.10 CRK35924.1 - 0.087 12.8 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_13 PF13880.6 CRK35924.1 - 0.1 12.6 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase PKcGMP_CC PF16808.5 CRK35925.1 - 0.43 10.5 8.2 0.077 12.9 4.5 1.6 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase zf-BED PF02892.15 CRK35925.1 - 1.1 9.3 3.6 10 6.2 0.1 2.6 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_4 PF13894.6 CRK35925.1 - 1.5 9.8 4.3 2.3 9.3 0.3 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger Methyltransf_11 PF08241.12 CRK35927.1 - 1.1e-15 58.0 0.0 2.9e-15 56.7 0.1 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CRK35927.1 - 5.4e-15 55.6 0.0 8.7e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK35927.1 - 9.6e-15 55.1 0.1 1.5e-14 54.4 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK35927.1 - 1.7e-14 53.9 0.0 2.4e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK35927.1 - 1.8e-09 38.3 0.0 2.7e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CRK35927.1 - 5.4e-07 29.2 0.0 8.1e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 CRK35927.1 - 5.9e-05 22.7 0.0 0.0001 21.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.11 CRK35927.1 - 0.00032 19.7 0.0 0.00048 19.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.6 CRK35927.1 - 0.0011 19.0 0.0 0.0016 18.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CRK35927.1 - 0.0023 17.3 0.0 0.0054 16.1 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 CRK35927.1 - 0.004 16.5 0.1 0.0056 16.0 0.1 1.1 1 0 0 1 1 1 1 O-methyltransferase domain PrmA PF06325.13 CRK35927.1 - 0.0058 16.1 0.1 0.0084 15.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 CRK35927.1 - 0.0097 15.7 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.7 CRK35927.1 - 0.034 14.1 0.0 0.05 13.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_PK PF05891.12 CRK35927.1 - 0.058 12.9 0.0 0.083 12.4 0.0 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Methyltransf_15 PF09445.10 CRK35927.1 - 0.085 12.4 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase ADH_zinc_N PF00107.26 CRK35927.1 - 0.22 11.5 0.8 0.5 10.4 0.8 1.6 1 1 0 1 1 1 0 Zinc-binding dehydrogenase ILVD_EDD PF00920.21 CRK35928.1 - 1.1e-147 492.9 0.0 1.3e-147 492.6 0.0 1.1 1 0 0 1 1 1 1 Dehydratase family Med10 PF09748.9 CRK35928.1 - 0.12 12.4 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Transcription factor subunit Med10 of Mediator complex FMO-like PF00743.19 CRK35929.1 - 7.9e-37 126.9 0.0 1.7e-15 56.5 0.0 3.0 2 1 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 CRK35929.1 - 4.8e-14 52.3 0.6 2e-12 47.0 0.1 1.9 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CRK35929.1 - 4.1e-10 39.4 0.0 1.4e-06 27.8 0.0 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CRK35929.1 - 1.7e-08 34.5 0.0 3.8e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 CRK35929.1 - 3.9e-08 32.8 0.1 0.0015 17.7 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 CRK35929.1 - 3.4e-07 30.2 0.1 0.0021 17.7 0.0 3.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 CRK35929.1 - 1.1e-06 28.8 0.0 3.4e-05 23.9 0.0 2.7 2 1 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 CRK35929.1 - 3.3e-05 23.2 0.0 0.00045 19.5 0.0 2.1 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 CRK35929.1 - 0.00058 20.4 0.4 0.11 13.0 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CRK35929.1 - 0.0056 15.4 0.3 0.012 14.4 0.0 1.6 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 CRK35929.1 - 0.0093 15.4 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CRK35929.1 - 0.011 14.8 0.0 0.057 12.5 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain ThiF PF00899.21 CRK35929.1 - 0.064 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 ThiF family AlaDh_PNT_C PF01262.21 CRK35929.1 - 0.069 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Glu_dehyd_C PF16912.5 CRK35929.1 - 0.13 11.7 0.0 0.67 9.4 0.0 2.0 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus MCRA PF06100.11 CRK35929.1 - 0.13 11.0 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 MCRA family Shikimate_DH PF01488.20 CRK35929.1 - 0.16 12.0 0.0 0.48 10.5 0.0 1.8 2 0 0 2 2 1 0 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.23 CRK35929.1 - 0.17 11.9 0.0 1.8 8.5 0.0 2.2 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Zn_clus PF00172.18 CRK35930.1 - 1e-06 28.7 8.1 1.5e-06 28.2 8.1 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 CRK35932.1 - 3.6e-07 30.2 11.3 6e-07 29.5 11.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RBR PF17208.3 CRK35932.1 - 0.26 12.0 0.3 0.26 12.0 0.3 2.5 3 0 0 3 3 3 0 RNA binding Region Dicty_REP PF05086.12 CRK35932.1 - 0.73 7.7 5.0 0.98 7.3 5.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein IMUP PF15761.5 CRK35932.1 - 2 9.1 8.5 0.31 11.7 2.1 2.4 2 0 0 2 2 2 0 Immortalisation up-regulated protein PAPA-1 PF04795.12 CRK35933.1 - 0.12 13.2 2.8 0.12 13.2 0.5 2.2 2 0 0 2 2 2 0 PAPA-1-like conserved region PKcGMP_CC PF16808.5 CRK35933.1 - 0.49 10.3 8.5 0.086 12.7 4.8 1.6 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase zf-C2H2_4 PF13894.6 CRK35933.1 - 0.88 10.6 3.5 2.3 9.3 0.3 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger Methyltransf_23 PF13489.6 CRK35935.1 - 1.2e-15 57.8 0.0 1.9e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CRK35935.1 - 2.1e-15 57.1 0.1 5.4e-15 55.8 0.1 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK35935.1 - 2e-14 54.0 0.2 3.2e-14 53.4 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK35935.1 - 2.6e-14 53.3 0.0 3.8e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK35935.1 - 2.1e-08 34.8 0.0 3.2e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CRK35935.1 - 9e-08 31.7 0.0 1.3e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 CRK35935.1 - 1.4e-05 24.7 0.1 2.6e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.11 CRK35935.1 - 0.00013 21.0 0.0 0.00019 20.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Ubie_methyltran PF01209.18 CRK35935.1 - 0.00028 20.3 0.0 0.00067 19.1 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 CRK35935.1 - 0.0003 20.8 0.0 0.00044 20.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 CRK35935.1 - 0.00059 19.3 0.1 0.00086 18.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 CRK35935.1 - 0.00065 19.5 0.0 0.00095 19.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.18 CRK35935.1 - 0.0021 17.4 0.2 0.0029 16.9 0.2 1.1 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_PK PF05891.12 CRK35935.1 - 0.02 14.4 0.0 0.027 14.0 0.0 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase TehB PF03848.14 CRK35935.1 - 0.025 14.0 0.0 0.038 13.4 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_18 PF12847.7 CRK35935.1 - 0.029 14.3 0.1 0.041 13.8 0.1 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_15 PF09445.10 CRK35935.1 - 0.12 11.9 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase ADH_zinc_N PF00107.26 CRK35935.1 - 0.13 12.2 1.0 0.27 11.2 1.0 1.5 1 1 0 1 1 1 0 Zinc-binding dehydrogenase TPMT PF05724.11 CRK35935.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) NodS PF05401.11 CRK35935.1 - 0.2 11.3 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) DOT1 PF08123.13 CRK35935.1 - 0.24 10.9 0.0 0.34 10.4 0.0 1.1 1 0 0 1 1 1 0 Histone methylation protein DOT1 ILVD_EDD PF00920.21 CRK35936.1 - 8e-150 499.9 0.0 9.8e-150 499.6 0.0 1.1 1 0 0 1 1 1 1 Dehydratase family Med10 PF09748.9 CRK35936.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Transcription factor subunit Med10 of Mediator complex Glyco_hydro_43 PF04616.14 CRK35937.1 - 1.6e-63 214.7 0.1 2.2e-63 214.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 CRK35937.1 - 1.1e-08 35.1 0.0 1.7e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain E1-E2_ATPase PF00122.20 CRK35938.1 - 9.6e-35 119.7 18.3 9.4e-28 96.9 0.0 3.7 3 1 1 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 CRK35938.1 - 3.3e-20 72.6 3.4 3.3e-20 72.6 3.4 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 CRK35938.1 - 7.6e-18 65.6 0.0 1.6e-16 61.2 0.0 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CRK35938.1 - 1.8e-16 60.0 0.0 4.8e-16 58.6 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 CRK35938.1 - 1.4e-15 56.7 0.0 3.5e-15 55.4 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CRK35938.1 - 0.0016 18.2 0.3 0.0029 17.4 0.3 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase PNK3P PF08645.11 CRK35939.1 - 2.4e-54 183.4 0.0 3.7e-54 182.8 0.0 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 CRK35939.1 - 1.1e-31 109.9 0.0 6.1e-29 101.0 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CRK35939.1 - 0.081 12.7 0.0 0.37 10.6 0.0 2.1 3 0 0 3 3 3 0 P-loop containing region of AAA domain Rad17 PF03215.15 CRK35939.1 - 0.1 12.5 0.0 0.37 10.7 0.0 1.8 2 0 0 2 2 2 0 Rad17 P-loop domain DUF3046 PF11248.8 CRK35939.1 - 0.13 12.7 0.1 3.9 7.9 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3046) RuvB_N PF05496.12 CRK35939.1 - 0.21 11.3 0.0 0.41 10.4 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain RsgA_GTPase PF03193.16 CRK35939.1 - 0.22 11.4 0.0 0.7 9.8 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase Zn_clus PF00172.18 CRK35940.1 - 2.2e-07 30.9 9.5 3.7e-07 30.2 9.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 CRK35940.1 - 0.004 16.0 0.8 0.0057 15.5 0.8 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Corona_nucleoca PF00937.18 CRK35941.1 - 0.0029 16.7 4.6 0.57 9.2 0.4 2.2 2 0 0 2 2 2 2 Coronavirus nucleocapsid protein gag_pre-integrs PF13976.6 CRK35941.1 - 0.063 13.1 0.1 17 5.3 0.0 2.4 2 0 0 2 2 2 0 GAG-pre-integrase domain Zein-binding PF04576.15 CRK35941.1 - 0.094 13.0 0.6 22 5.4 0.1 2.4 2 0 0 2 2 2 0 Zein-binding C_Hendra PF16821.5 CRK35941.1 - 0.096 12.6 0.7 16 5.4 0.1 2.3 2 0 0 2 2 2 0 C protein from hendra and measles viruses DUF5405 PF17399.2 CRK35941.1 - 0.13 12.6 0.1 26 5.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5405) DUF1033 PF06279.11 CRK35941.1 - 0.54 10.5 3.4 17 5.6 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1033) TPIP1 PF15338.6 CRK35941.1 - 2 8.5 4.9 23 5.1 0.4 2.3 2 0 0 2 2 2 0 p53-regulated apoptosis-inducing protein 1 Cation_ATPase_C PF00689.21 CRK35942.1 - 6.9e-22 78.0 3.6 1.2e-21 77.3 3.6 1.3 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus PNK3P PF08645.11 CRK35943.1 - 2.6e-55 186.6 0.0 4.1e-55 185.9 0.0 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 CRK35943.1 - 1.1e-31 109.9 0.0 4.8e-29 101.4 0.0 2.6 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 CRK35943.1 - 0.033 14.1 0.0 0.15 11.9 0.0 2.0 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_29 PF13555.6 CRK35943.1 - 0.1 12.4 0.0 0.36 10.6 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF3046 PF11248.8 CRK35943.1 - 0.13 12.7 0.2 3.9 7.9 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3046) KTI12 PF08433.10 CRK35943.1 - 0.15 11.5 0.2 13 5.1 0.0 2.3 1 1 1 2 2 2 0 Chromatin associated protein KTI12 RuvB_N PF05496.12 CRK35943.1 - 0.18 11.5 0.0 0.35 10.6 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Med18 PF09637.10 CRK35944.1 - 5.2e-24 85.4 0.0 6.2e-24 85.2 0.0 1.1 1 0 0 1 1 1 1 Med18 protein IGF2_C PF08365.11 CRK35944.1 - 0.078 13.0 0.1 0.25 11.4 0.1 1.9 1 0 0 1 1 1 0 Insulin-like growth factor II E-peptide FRP PF18032.1 CRK35944.1 - 0.35 11.5 1.5 8.1 7.1 0.1 2.6 3 0 0 3 3 3 0 Photoprotection regulator fluorescence recovery protein MFS_1 PF07690.16 CRK35947.1 - 8.6e-26 90.7 32.2 8.6e-26 90.7 32.2 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK35947.1 - 3.3e-12 46.0 21.5 6.7e-12 45.0 21.5 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter ATG22 PF11700.8 CRK35947.1 - 9.9e-08 31.0 2.7 9.9e-08 31.0 2.7 2.9 2 1 1 3 3 3 2 Vacuole effluxer Atg22 like TRI12 PF06609.13 CRK35947.1 - 9.7e-05 21.0 0.8 9.7e-05 21.0 0.8 2.6 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Cyclase PF04199.13 CRK35948.1 - 5.2e-14 52.7 0.1 6.8e-14 52.3 0.1 1.2 1 0 0 1 1 1 1 Putative cyclase Aminotran_1_2 PF00155.21 CRK35949.1 - 1.5e-18 67.1 0.0 1.7e-17 63.7 0.0 2.0 1 1 1 2 2 2 2 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 CRK35949.1 - 0.026 13.1 0.0 0.041 12.4 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 CRK35949.1 - 0.061 12.6 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase adh_short PF00106.25 CRK35950.1 - 2.1e-25 89.3 3.6 3.7e-17 62.4 2.5 2.7 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CRK35950.1 - 4.6e-19 68.9 1.5 2.1e-10 40.6 0.3 3.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK35950.1 - 1.7e-05 24.8 0.5 4.1e-05 23.6 0.4 1.6 1 1 1 2 2 2 1 KR domain NAD_binding_10 PF13460.6 CRK35950.1 - 0.032 14.1 0.0 0.054 13.4 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding zf-C2H2 PF00096.26 CRK35951.1 - 0.52 10.9 0.0 0.52 10.9 0.0 2.2 3 0 0 3 3 3 0 Zinc finger, C2H2 type DIOX_N PF14226.6 CRK35952.1 - 4.8e-24 85.4 0.0 8e-24 84.7 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 CRK35952.1 - 1.4e-11 44.8 0.0 6.2e-11 42.7 0.0 2.1 3 0 0 3 3 3 1 2OG-Fe(II) oxygenase superfamily Peptidase_M54 PF07998.11 CRK35953.1 - 1.5e-07 31.6 0.2 2.5e-07 30.9 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M54 Peptidase_M10 PF00413.24 CRK35953.1 - 0.004 17.0 0.0 0.0063 16.4 0.0 1.3 1 0 0 1 1 1 1 Matrixin Metallopep PF12044.8 CRK35953.1 - 0.12 10.9 0.2 0.18 10.4 0.2 1.2 1 0 0 1 1 1 0 Putative peptidase family Peptidase_M66 PF10462.9 CRK35953.1 - 0.15 10.9 0.1 0.24 10.3 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 ADH_zinc_N PF00107.26 CRK35954.1 - 1e-19 70.8 0.1 2.7e-19 69.4 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CRK35954.1 - 6e-16 58.3 2.4 1.3e-15 57.2 2.4 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain 2-Hacid_dh_C PF02826.19 CRK35954.1 - 0.00056 19.3 0.2 0.0013 18.1 0.1 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 CRK35954.1 - 0.0011 18.3 0.1 0.0018 17.6 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain CTP_transf_like PF01467.26 CRK35955.1 - 1.1e-06 28.9 0.0 3e-05 24.2 0.0 2.3 2 0 0 2 2 2 1 Cytidylyltransferase-like DUF2229 PF09989.9 CRK35955.1 - 0.1 12.2 0.0 0.92 9.1 0.0 2.2 2 0 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) DUF1674 PF07896.12 CRK35956.1 - 8.9e-19 67.7 3.9 2.3e-18 66.4 3.9 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1674) Rxt3 PF08642.10 CRK35957.1 - 2.3e-43 148.0 0.2 2.3e-43 148.0 0.2 2.5 3 0 0 3 3 3 1 Histone deacetylation protein Rxt3 LCCL PF03815.19 CRK35957.1 - 0.00067 19.7 0.0 0.012 15.7 0.0 2.4 2 0 0 2 2 2 1 LCCL domain Zn_clus PF00172.18 CRK35958.1 - 3.4e-06 27.1 11.9 6.3e-06 26.2 11.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rep_fac-A_C PF08646.10 CRK35958.1 - 0.013 15.2 0.3 0.022 14.5 0.3 1.3 1 0 0 1 1 1 0 Replication factor-A C terminal domain ChuX_HutX PF06228.13 CRK35958.1 - 0.097 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Haem utilisation ChuX/HutX 1-cysPrx_C PF10417.9 CRK35959.1 - 0.11 12.3 2.7 4.4 7.2 0.0 2.9 3 0 0 3 3 3 0 C-terminal domain of 1-Cys peroxiredoxin eIF2_C PF09173.11 CRK35961.1 - 2e-34 117.7 0.5 3.2e-34 117.0 0.5 1.3 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.25 CRK35961.1 - 7.4e-11 42.3 0.2 1.4e-10 41.4 0.2 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 CMAS PF02353.20 CRK35963.1 - 2.2e-08 33.7 0.0 2.3e-08 33.7 0.0 1.0 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Tho1_MOS11_C PF18592.1 CRK35966.1 - 2.2e-07 30.6 2.1 0.011 15.6 0.2 2.2 1 1 1 2 2 2 2 Tho1/MOS11 C-terminal domain WD40 PF00400.32 CRK35969.1 - 0.0043 17.9 0.2 2.5 9.1 0.0 2.9 3 0 0 3 3 3 2 WD domain, G-beta repeat Haspin_kinase PF12330.8 CRK35970.1 - 5.7e-05 22.2 0.0 6.2e-05 22.1 0.0 1.0 1 0 0 1 1 1 1 Haspin like kinase domain MIF4G PF02854.19 CRK35972.1 - 1.6e-25 90.0 0.0 1.8e-25 89.8 0.0 1.1 1 0 0 1 1 1 1 MIF4G domain GMC_oxred_N PF00732.19 CRK35974.1 - 1.8e-09 37.4 0.1 1.9e-09 37.3 0.1 1.0 1 0 0 1 1 1 1 GMC oxidoreductase Acyl-CoA_dh_N PF02771.16 CRK35976.1 - 1.3e-10 41.9 0.0 2.2e-10 41.2 0.0 1.4 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain SRP54 PF00448.22 CRK35979.1 - 2.2e-37 128.6 0.1 2.4e-37 128.5 0.1 1.0 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_33 PF13671.6 CRK35979.1 - 4.5e-06 26.9 0.0 5.4e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 CRK35979.1 - 0.00026 20.7 0.2 0.00058 19.6 0.1 1.6 1 1 1 2 2 2 1 Thymidylate kinase AAA_17 PF13207.6 CRK35979.1 - 0.00043 20.7 0.2 0.00055 20.4 0.2 1.4 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CRK35979.1 - 0.0005 19.8 0.0 0.00056 19.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 CRK35979.1 - 0.00078 18.8 0.0 0.00085 18.7 0.0 1.1 1 0 0 1 1 1 1 Zeta toxin ATP_bind_1 PF03029.17 CRK35979.1 - 0.0014 18.5 0.1 0.0029 17.4 0.1 1.6 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 CRK35979.1 - 0.0021 18.6 0.0 0.0023 18.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.20 CRK35979.1 - 0.0028 17.6 0.0 0.0044 16.9 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase CbiA PF01656.23 CRK35979.1 - 0.0034 17.4 0.4 0.0074 16.3 0.3 1.6 1 1 1 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.6 CRK35979.1 - 0.0044 17.4 0.0 0.0045 17.4 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain MobB PF03205.14 CRK35979.1 - 0.006 16.5 0.2 0.012 15.6 0.1 1.6 1 1 1 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.6 CRK35979.1 - 0.0068 16.7 0.2 0.0078 16.5 0.2 1.3 1 1 0 1 1 1 1 AAA domain AAA_31 PF13614.6 CRK35979.1 - 0.013 15.4 0.1 0.029 14.3 0.1 1.6 1 1 0 1 1 1 0 AAA domain ResIII PF04851.15 CRK35979.1 - 0.015 15.3 0.7 0.056 13.4 0.7 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_19 PF13245.6 CRK35979.1 - 0.016 15.6 0.1 0.018 15.4 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CRK35979.1 - 0.02 15.2 0.3 0.027 14.8 0.3 1.5 1 1 0 1 1 1 0 AAA domain MeaB PF03308.16 CRK35979.1 - 0.037 13.0 0.1 0.073 12.0 0.1 1.7 1 1 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF1611 PF07755.11 CRK35979.1 - 0.039 13.2 0.3 0.041 13.2 0.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1611_C) P-loop domain AAA_24 PF13479.6 CRK35979.1 - 0.047 13.4 0.0 0.064 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 CRK35979.1 - 0.057 13.8 0.2 0.064 13.7 0.2 1.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Cytidylate_kin PF02224.18 CRK35979.1 - 0.067 12.9 0.0 0.076 12.7 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase NTPase_1 PF03266.15 CRK35979.1 - 0.086 12.7 0.2 0.2 11.6 0.1 1.6 1 1 0 1 1 1 0 NTPase TrwB_AAD_bind PF10412.9 CRK35979.1 - 0.096 11.6 0.2 0.15 11.0 0.0 1.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain ADK PF00406.22 CRK35979.1 - 0.11 12.6 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Adenylate kinase LpxK PF02606.14 CRK35979.1 - 0.11 11.5 0.1 0.23 10.5 0.1 1.5 2 0 0 2 2 2 0 Tetraacyldisaccharide-1-P 4'-kinase Hydin_ADK PF17213.3 CRK35979.1 - 0.14 12.4 0.4 0.28 11.4 0.3 1.5 1 1 1 2 2 2 0 Hydin Adenylate kinase-like domain TPR_2 PF07719.17 CRK35980.1 - 1.5e-12 46.6 1.4 9.4e-06 25.4 0.1 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 CRK35980.1 - 3.6e-11 42.4 1.4 4.6e-05 23.0 0.1 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 CRK35980.1 - 4.6e-09 36.0 0.1 0.13 12.7 0.1 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 CRK35980.1 - 3.3e-06 26.7 3.1 0.016 14.9 0.2 2.9 2 1 1 3 3 3 2 TPR repeat TPR_9 PF13371.6 CRK35980.1 - 3.3e-06 27.1 0.0 4.1e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 CRK35980.1 - 0.00055 20.5 0.2 0.017 15.9 0.0 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 CRK35980.1 - 0.00064 20.2 0.4 0.0022 18.5 0.2 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 CRK35980.1 - 0.0009 19.0 0.2 0.061 13.2 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 CRK35980.1 - 0.0028 17.7 0.2 4.1 7.9 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 CRK35980.1 - 0.0033 18.0 0.1 0.0054 17.3 0.1 1.4 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_20 PF14561.6 CRK35980.1 - 0.0063 16.8 0.2 0.49 10.8 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 CRK35980.1 - 0.0071 16.6 0.5 0.041 14.2 0.5 2.0 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_21 PF09976.9 CRK35980.1 - 0.0098 15.6 0.4 0.012 15.3 0.4 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat-like domain Chol_subst-bind PF09129.11 CRK35980.1 - 0.12 11.3 0.2 0.22 10.4 0.2 1.4 1 1 1 2 2 2 0 Cholesterol oxidase, substrate-binding Ribosomal_L6 PF00347.23 CRK35983.1 - 4.2e-11 43.4 0.0 6.7e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L6 tRNA-synt_1c PF00749.21 CRK35996.1 - 6.1e-105 350.6 0.0 7.8e-105 350.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain COG2 PF06148.11 CRK35996.1 - 1.1e-24 87.0 2.1 2.3e-24 86.0 0.2 2.4 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.11 CRK35996.1 - 0.00014 21.9 0.0 0.0004 20.4 0.0 1.9 1 0 0 1 1 1 1 Vps51/Vps67 tRNA-synt_1e PF01406.19 CRK35996.1 - 0.00081 18.8 0.2 0.0025 17.2 0.1 1.6 1 1 1 2 2 2 1 tRNA synthetases class I (C) catalytic domain Spc7 PF08317.11 CRK35996.1 - 0.008 15.1 0.2 0.014 14.3 0.2 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein COG5 PF10392.9 CRK35996.1 - 0.021 15.0 0.0 0.047 13.9 0.0 1.6 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Dor1 PF04124.12 CRK35996.1 - 0.077 11.7 0.2 0.12 11.0 0.2 1.2 1 0 0 1 1 1 0 Dor1-like family Vps54_N PF10475.9 CRK35996.1 - 0.16 11.2 0.1 0.33 10.2 0.0 1.6 2 0 0 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex Fez1 PF06818.15 CRK35996.1 - 0.22 12.0 1.0 0.36 11.3 0.2 1.7 2 0 0 2 2 2 0 Fez1 DUF998 PF06197.13 CRK35999.1 - 0.026 14.1 9.4 0.031 13.9 9.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF998) DUF2275 PF10039.9 CRK35999.1 - 0.4 10.8 0.8 0.45 10.6 0.8 1.1 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2275) PIG-U PF06728.13 CRK36001.1 - 1.2e-78 264.9 13.8 1.2e-78 264.9 13.8 1.5 2 0 0 2 2 2 1 GPI transamidase subunit PIG-U MFS_1 PF07690.16 CRK36002.1 - 2.2e-17 63.0 23.1 2.4e-17 62.9 23.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 CRK36002.1 - 0.0033 15.9 6.5 0.0036 15.8 6.5 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 CRK36002.1 - 0.04 12.8 12.6 0.074 11.9 12.6 1.4 1 1 0 1 1 1 0 Sugar (and other) transporter CRM1_repeat PF18777.1 CRK36005.1 - 8.4e-21 73.2 1.8 1.1e-20 72.8 1.8 1.2 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat Alg6_Alg8 PF03155.15 CRK36007.1 - 5.5e-59 200.4 7.5 6.4e-59 200.2 7.5 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Peptidase_M24 PF00557.24 CRK36007.1 - 4.3e-05 23.3 0.0 5.7e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 MerC PF03203.14 CRK36007.1 - 5.8 7.4 10.7 3.4 8.2 7.2 2.3 1 1 1 2 2 2 0 MerC mercury resistance protein RskA PF10099.9 CRK36008.1 - 1.9 8.8 10.9 4.5 7.5 9.3 1.7 1 1 1 2 2 2 0 Anti-sigma-K factor rskA Actin PF00022.19 CRK36010.1 - 2.7e-75 253.5 0.0 2.6e-39 135.0 0.0 2.0 1 1 1 2 2 2 2 Actin Cation_ATPase_C PF00689.21 CRK36011.1 - 1.3e-18 67.4 0.3 1.4e-18 67.2 0.3 1.0 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus NAD_binding_4 PF07993.12 CRK36014.1 - 8.1e-18 64.5 0.0 9.2e-18 64.3 0.0 1.0 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 CRK36014.1 - 0.039 13.4 0.0 0.045 13.2 0.0 1.0 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CRK36014.1 - 0.049 12.6 0.1 0.053 12.5 0.1 1.0 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family RNA_pol_Rpb1_6 PF04992.14 CRK36015.1 - 4.5e-61 206.0 1.1 6.9e-61 205.4 1.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_5 PF04998.17 CRK36015.1 - 7.2e-31 107.6 0.0 8.9e-31 107.3 0.0 1.2 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 ANAPC4_WD40 PF12894.7 CRK36015.1 - 0.022 15.0 0.7 2.8 8.3 0.1 3.4 1 1 3 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain DIRP PF06584.13 CRK36015.1 - 0.062 13.5 0.3 0.17 12.1 0.3 1.7 1 0 0 1 1 1 0 DIRP zf-C3HC4 PF00097.25 CRK36016.1 - 1.3e-09 37.7 2.5 2.7e-09 36.7 2.5 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CRK36016.1 - 7.9e-09 35.4 0.8 7.9e-09 35.4 0.8 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 CRK36016.1 - 8.9e-08 32.0 4.0 2.4e-07 30.6 4.0 1.7 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CRK36016.1 - 1.4e-07 31.3 5.7 6.9e-07 29.0 1.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CRK36016.1 - 1.6e-07 31.6 5.9 2.9e-07 30.7 5.9 1.5 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CRK36016.1 - 1.6e-07 31.0 6.8 3.7e-07 29.9 6.8 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CRK36016.1 - 2.4e-06 27.6 6.3 3.1e-05 24.0 6.8 2.1 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-MIZ PF02891.20 CRK36016.1 - 0.0017 18.1 6.7 0.35 10.6 3.9 2.6 2 1 0 2 2 2 2 MIZ/SP-RING zinc finger Prok-RING_4 PF14447.6 CRK36016.1 - 0.0024 17.7 13.3 0.12 12.3 13.2 2.8 1 1 1 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 CRK36016.1 - 0.0097 16.0 1.3 0.0097 16.0 1.3 1.7 2 0 0 2 2 2 1 zinc RING finger of MSL2 zf-ribbon_3 PF13248.6 CRK36016.1 - 0.029 13.8 4.8 0.42 10.1 1.0 2.6 2 1 0 2 2 2 0 zinc-ribbon domain zf-rbx1 PF12678.7 CRK36016.1 - 0.11 12.8 7.6 0.59 10.5 7.6 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 CRK36016.1 - 0.33 10.8 4.7 2.7 7.9 3.1 2.4 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain TerY_C PF15616.6 CRK36016.1 - 0.73 10.0 5.9 0.098 12.8 1.8 1.7 1 1 1 2 2 2 0 TerY-C metal binding domain FYVE PF01363.21 CRK36016.1 - 0.91 9.7 6.1 7.5 6.8 6.1 2.3 1 1 0 1 1 1 0 FYVE zinc finger Lar_restr_allev PF14354.6 CRK36016.1 - 3.7 8.0 8.5 0.53 10.7 1.6 2.2 1 1 1 2 2 2 0 Restriction alleviation protein Lar zf-RING_11 PF17123.5 CRK36016.1 - 4 7.3 11.8 0.73 9.6 5.8 2.6 2 1 0 2 2 2 0 RING-like zinc finger Zn-C2H2_12 PF18112.1 CRK36016.1 - 5.5 7.5 7.9 2.8 8.5 1.0 2.5 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain Glyco_hydro_18 PF00704.28 CRK36019.1 - 1.7e-24 87.1 0.0 1.9e-24 87.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DEAD PF00270.29 CRK36020.1 - 1.2e-12 47.9 0.1 1.6e-12 47.5 0.1 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase UvrD-helicase PF00580.21 CRK36020.1 - 0.086 12.3 0.1 0.11 12.0 0.1 1.1 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain MCM PF00493.23 CRK36021.1 - 1.1e-50 171.8 0.1 1.2e-50 171.7 0.1 1.0 1 0 0 1 1 1 1 MCM P-loop domain Mg_chelatase PF01078.21 CRK36021.1 - 2e-07 30.6 0.0 2e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CRK36021.1 - 0.0032 17.3 0.0 0.0035 17.2 0.0 1.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CRK36021.1 - 0.015 15.0 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_5 PF07728.14 CRK36021.1 - 0.045 13.7 0.0 0.065 13.2 0.0 1.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) G6PD_N PF00479.22 CRK36022.1 - 9e-15 55.8 0.0 9.7e-15 55.6 0.0 1.0 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain RNase_H2-Ydr279 PF09468.10 CRK36022.1 - 0.002 18.3 0.1 0.0038 17.4 0.1 1.3 1 1 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Cg6151-P PF10233.9 CRK36023.1 - 1.6e-34 118.6 11.4 1.7e-34 118.5 11.4 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P DUF4577 PF15145.6 CRK36023.1 - 2 8.5 4.0 3.4 7.7 4.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4577) UL41A PF17591.2 CRK36023.1 - 6.9 6.9 8.6 2.6 8.2 6.2 1.6 2 1 0 2 2 2 0 Herpesvirus UL41A XPG_I PF00867.18 CRK36024.1 - 2.5e-30 104.6 1.7 6.2e-30 103.4 0.0 2.1 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.20 CRK36024.1 - 1.2e-05 25.9 0.5 0.00011 22.7 0.0 2.3 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold MRPL52 PF18699.1 CRK36024.1 - 0.71 10.1 9.7 1.3 9.3 7.2 2.3 2 0 0 2 2 2 0 Mitoribosomal protein mL52 Pannexin_like PF12534.8 CRK36024.1 - 7.4 5.6 5.2 10 5.1 5.2 1.1 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 LrgB PF04172.16 CRK36025.1 - 3e-108 360.3 32.5 8e-56 188.9 12.5 2.7 2 0 0 2 2 2 2 LrgB-like family Cyt-b5 PF00173.28 CRK36025.1 - 5.5e-20 71.3 0.4 1.2e-19 70.3 0.4 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF4094 PF13334.6 CRK36025.1 - 0.11 12.9 0.0 38 4.8 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) THOC2_N PF16134.5 CRK36025.1 - 0.15 10.7 0.1 4.8 5.7 0.0 2.1 2 0 0 2 2 2 0 THO complex subunit 2 N-terminus MFS_1 PF07690.16 CRK36026.1 - 1.6e-20 73.4 50.9 4.8e-20 71.8 49.2 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily LrgB PF04172.16 CRK36027.1 - 6.4e-45 153.3 3.8 7.9e-45 153.0 3.8 1.0 1 0 0 1 1 1 1 LrgB-like family MFS_1 PF07690.16 CRK36028.1 - 1.1e-16 60.7 50.6 4e-12 45.7 26.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily FAD_binding_3 PF01494.19 CRK36029.1 - 6.3e-55 186.8 0.5 1.5e-54 185.5 0.5 1.6 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 CRK36029.1 - 0.0022 17.1 1.3 0.61 9.1 0.0 2.4 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_3 PF13738.6 CRK36029.1 - 0.0066 15.7 1.2 1.3 8.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CRK36029.1 - 0.054 12.7 0.2 2.8 7.1 0.2 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CRK36029.1 - 0.15 11.3 0.4 0.42 9.8 0.1 1.8 2 0 0 2 2 2 0 Thi4 family DIT1_PvcA PF05141.12 CRK36030.1 - 1.9e-72 244.1 0.0 6.8e-43 147.1 0.0 2.1 1 1 1 2 2 2 2 Pyoverdine/dityrosine biosynthesis protein TauD PF02668.16 CRK36030.1 - 2.6e-24 86.5 0.4 1.1e-22 81.1 0.3 3.3 2 1 0 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family DEAD PF00270.29 CRK36031.1 - 2.7e-43 147.8 0.0 4.3e-43 147.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CRK36031.1 - 9.5e-28 96.8 0.5 8.1e-27 93.8 0.3 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.6 CRK36031.1 - 0.16 11.2 0.0 0.39 10.0 0.0 1.6 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit API5 PF05918.11 CRK36031.1 - 2.8 6.7 14.8 4.8 5.9 14.8 1.4 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) TFIIA PF03153.13 CRK36031.1 - 4.9 7.0 19.3 8.7 6.2 19.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DnaJ PF00226.31 CRK36032.1 - 0.065 13.4 0.2 0.12 12.5 0.2 1.4 1 0 0 1 1 1 0 DnaJ domain GatB_N PF02934.15 CRK36033.1 - 5.7e-99 330.9 0.0 8.3e-99 330.4 0.0 1.2 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 CRK36033.1 - 1.3e-09 38.1 0.4 6.1e-09 35.9 0.0 2.1 2 0 0 2 2 2 1 GatB domain DUF2802 PF10975.8 CRK36034.1 - 0.09 12.9 0.7 0.2 11.8 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) DUF1961 PF09224.11 CRK36036.1 - 2.9e-104 347.1 0.0 3.3e-104 346.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1961) DUF1080 PF06439.11 CRK36036.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.6 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1080) Fasciclin PF02469.22 CRK36038.1 - 6.7e-51 171.8 4.4 2.1e-30 105.6 1.1 2.1 2 0 0 2 2 2 2 Fasciclin domain Glyco_transf_28 PF03033.20 CRK36039.1 - 5.6e-18 65.3 0.1 2.2e-16 60.1 0.1 2.6 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 CRK36039.1 - 4.1e-07 29.2 0.1 6.5e-07 28.5 0.1 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CRK36039.1 - 0.081 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain DUF2985 PF11204.8 CRK36040.1 - 5.6e-38 129.0 0.4 5.6e-38 129.0 0.4 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) Phage_holin_3_6 PF07332.11 CRK36040.1 - 0.16 12.0 2.2 0.85 9.7 0.1 2.2 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Bac_rhamnosid_C PF17390.2 CRK36041.1 - 1.1e-07 31.6 0.0 2.3e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Bac_rhamnosid6H PF17389.2 CRK36041.1 - 0.0022 17.3 0.0 0.0058 15.9 0.0 1.5 1 1 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain DUF608 PF04685.13 CRK36041.1 - 0.19 10.9 0.1 0.29 10.2 0.1 1.2 1 0 0 1 1 1 0 Glycosyl-hydrolase family 116, catalytic region DUF1961 PF09224.11 CRK36042.1 - 4.8e-29 101.3 0.0 7.4e-29 100.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1961) Fasciclin PF02469.22 CRK36044.1 - 2.9e-50 169.8 4.8 2.2e-30 105.5 1.1 2.1 2 0 0 2 2 2 2 Fasciclin domain Glyco_transf_28 PF03033.20 CRK36045.1 - 6.7e-18 65.1 0.1 2.2e-16 60.1 0.1 2.4 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 CRK36045.1 - 3.4e-07 29.4 0.2 5.2e-07 28.8 0.2 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CRK36045.1 - 0.14 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain DUF2985 PF11204.8 CRK36046.1 - 7.1e-38 128.6 0.4 7.1e-38 128.6 0.4 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) Phage_holin_3_6 PF07332.11 CRK36046.1 - 0.073 13.1 2.4 0.29 11.2 0.1 2.2 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Bac_rhamnosid_C PF17390.2 CRK36047.1 - 5.6e-11 42.1 0.0 2e-10 40.3 0.0 1.9 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase C-terminal domain Bac_rhamnosid6H PF17389.2 CRK36047.1 - 4.3e-08 32.8 0.0 2.6e-06 26.9 0.0 2.4 2 1 0 2 2 2 2 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain DUF2600 PF10776.9 CRK36047.1 - 0.058 12.3 0.0 0.09 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2600) Jun PF03957.13 CRK36049.1 - 0.029 14.3 0.0 0.036 13.9 0.0 1.1 1 0 0 1 1 1 0 Jun-like transcription factor Reovirus_M2 PF05993.12 CRK36049.1 - 0.19 9.8 0.2 0.23 9.5 0.2 1.0 1 0 0 1 1 1 0 Reovirus major virion structural protein Mu-1/Mu-1C (M2) EphA2_TM PF14575.6 CRK36050.1 - 0.16 12.8 0.0 0.4 11.6 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Apt1 PF10351.9 CRK36050.1 - 1.3 7.8 2.9 1.7 7.4 2.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain EphA2_TM PF14575.6 CRK36051.1 - 0.16 12.9 0.0 0.32 11.9 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Apt1 PF10351.9 CRK36051.1 - 0.24 10.2 2.7 0.29 10.0 2.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Ion_trans PF00520.31 CRK36052.1 - 3.5e-06 26.4 12.9 6.4e-06 25.6 12.9 1.3 1 0 0 1 1 1 1 Ion transport protein CENP-B_dimeris PF09026.10 CRK36052.1 - 0.016 15.6 1.2 2 8.8 0.1 2.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain PKD_channel PF08016.12 CRK36052.1 - 0.061 12.0 5.2 2.2 6.9 5.2 2.1 1 1 0 1 1 1 0 Polycystin cation channel Vps36_ESCRT-II PF11605.8 CRK36053.1 - 1.8e-24 85.7 0.0 2.7e-24 85.2 0.0 1.2 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 Vps36-NZF-N PF16988.5 CRK36053.1 - 7e-24 83.0 2.5 7e-24 83.0 2.5 2.9 2 1 0 2 2 2 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-Sec23_Sec24 PF04810.15 CRK36053.1 - 0.00015 21.7 4.6 0.011 15.8 0.2 2.5 2 0 0 2 2 2 2 Sec23/Sec24 zinc finger zf-RanBP PF00641.18 CRK36053.1 - 0.00033 19.9 11.4 0.001 18.3 0.5 2.7 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others GRAM PF02893.20 CRK36053.1 - 0.0024 17.7 0.0 0.0041 17.0 0.0 1.3 1 0 0 1 1 1 1 GRAM domain EAP30 PF04157.16 CRK36053.1 - 0.011 15.1 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 EAP30/Vps36 family DZR PF12773.7 CRK36053.1 - 0.054 13.5 0.7 0.054 13.5 0.7 2.3 2 1 0 2 2 2 0 Double zinc ribbon PHD PF00628.29 CRK36053.1 - 0.24 11.3 2.3 14 5.7 0.1 3.1 3 0 0 3 3 3 0 PHD-finger SAC3_GANP PF03399.16 CRK36055.1 - 2.7e-13 49.9 0.1 3.5e-13 49.6 0.1 1.2 1 0 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 CRK36055.1 - 0.015 15.3 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family Thymidylat_synt PF00303.19 CRK36057.1 - 1.8e-105 351.9 0.0 2.5e-105 351.4 0.0 1.1 1 0 0 1 1 1 1 Thymidylate synthase HTH_Tnp_Tc5 PF03221.16 CRK36057.1 - 5.1e-18 64.8 0.2 1.3e-17 63.5 0.2 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_ABP1_N PF18107.1 CRK36057.1 - 5.8e-14 51.5 0.1 1.3e-13 50.4 0.1 1.6 1 0 0 1 1 1 1 Fission yeast centromere protein N-terminal domain DUF5321 PF17254.2 CRK36057.1 - 0.021 14.3 0.4 0.042 13.3 0.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5321) HET PF06985.11 CRK36059.1 - 8.1e-25 87.9 0.0 1.3e-24 87.2 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Headcase PF16002.5 CRK36059.1 - 0.012 15.1 0.3 5.8 6.3 0.0 2.5 2 0 0 2 2 2 0 Headcase protein DUF3742 PF12553.8 CRK36059.1 - 0.81 9.8 2.8 26 5.0 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3742) EAP30 PF04157.16 CRK36061.1 - 7.6e-44 149.8 0.3 1.1e-43 149.2 0.3 1.3 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36-NZF-N PF16988.5 CRK36061.1 - 1.5e-23 82.0 2.7 1.5e-23 82.0 2.7 2.6 2 1 0 2 2 2 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain Vps36_ESCRT-II PF11605.8 CRK36061.1 - 5.9e-15 55.2 0.0 1e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-Sec23_Sec24 PF04810.15 CRK36061.1 - 0.00064 19.7 5.1 0.018 15.1 0.2 2.4 2 0 0 2 2 2 2 Sec23/Sec24 zinc finger zf-RanBP PF00641.18 CRK36061.1 - 0.0014 17.9 0.4 0.0014 17.9 0.4 2.6 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others GRAM PF02893.20 CRK36061.1 - 0.0046 16.8 0.0 0.0087 15.9 0.0 1.4 1 0 0 1 1 1 1 GRAM domain DZR PF12773.7 CRK36061.1 - 1.7 8.7 7.0 0.16 12.0 0.8 2.2 2 1 0 2 2 2 0 Double zinc ribbon SAC3_GANP PF03399.16 CRK36063.1 - 2e-25 89.8 1.0 3.1e-23 82.6 1.0 2.1 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 CRK36063.1 - 0.087 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family SH3_1 PF00018.28 CRK36065.1 - 1.4e-58 194.2 0.1 5.6e-14 51.5 0.0 4.4 4 0 0 4 4 4 4 SH3 domain SH3_9 PF14604.6 CRK36065.1 - 5.1e-39 131.9 0.7 2.3e-09 36.9 0.1 4.9 4 0 0 4 4 4 4 Variant SH3 domain SH3_2 PF07653.17 CRK36065.1 - 5e-24 83.7 0.0 2e-07 30.5 0.0 4.4 4 0 0 4 4 4 4 Variant SH3 domain PX PF00787.24 CRK36065.1 - 1.5e-12 47.5 0.0 2.8e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 PX domain PB1 PF00564.24 CRK36065.1 - 3.5e-08 33.3 0.0 5.8e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 PB1 domain Rad60-SLD PF11976.8 CRK36065.1 - 0.00049 19.9 0.1 0.0019 18.0 0.1 2.0 1 1 1 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like GH97_C PF14509.6 CRK36065.1 - 0.056 13.7 0.0 22 5.4 0.0 2.6 2 0 0 2 2 2 0 Glycosyl-hydrolase 97 C-terminal, oligomerisation FOG_N PF15888.5 CRK36065.1 - 0.085 13.2 0.2 40 4.6 0.0 4.0 4 0 0 4 4 4 0 Folded gastrulation N-terminus DUF5310 PF17237.2 CRK36065.1 - 2.1 8.3 9.5 6.1 6.8 0.0 3.3 4 0 0 4 4 4 0 Family of unknown function (DUF5310) Thymidylat_synt PF00303.19 CRK36068.1 - 2e-105 351.7 0.0 2.8e-105 351.3 0.0 1.2 1 0 0 1 1 1 1 Thymidylate synthase HTH_Tnp_Tc5 PF03221.16 CRK36068.1 - 5.4e-18 64.8 0.2 1.4e-17 63.5 0.2 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_ABP1_N PF18107.1 CRK36068.1 - 6.1e-14 51.5 0.1 1.4e-13 50.4 0.1 1.6 1 0 0 1 1 1 1 Fission yeast centromere protein N-terminal domain DUF5321 PF17254.2 CRK36068.1 - 0.023 14.2 0.4 0.044 13.2 0.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5321) MTP18 PF10558.9 CRK36070.1 - 7.4e-84 279.9 0.2 9.2e-84 279.6 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) Rad4 PF03835.15 CRK36072.1 - 1.6e-32 112.2 0.2 1.6e-32 112.2 0.2 2.3 3 0 0 3 3 3 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 CRK36072.1 - 7.3e-27 93.6 0.6 2.1e-26 92.1 0.6 1.8 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 CRK36072.1 - 6.2e-18 64.4 0.1 1.3e-17 63.4 0.1 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 CRK36072.1 - 4.3e-15 56.4 0.2 4.3e-15 56.4 0.2 6.1 7 1 0 7 7 7 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 CRK36072.1 - 0.0017 18.8 0.3 0.0069 16.8 0.1 2.3 2 1 0 2 2 2 1 Transglutaminase-like superfamily Dcc1 PF09724.9 CRK36073.1 - 7.2e-05 22.2 0.0 9.2e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 RhoGEF PF00621.20 CRK36074.1 - 1.4e-27 97.2 1.0 3.8e-27 95.7 0.1 2.2 2 0 0 2 2 2 1 RhoGEF domain PTase_Orf2 PF11468.8 CRK36074.1 - 0.034 13.5 0.0 11 5.3 0.0 2.5 2 0 0 2 2 2 0 Aromatic prenyltransferase Orf2 FAF PF11250.8 CRK36074.1 - 0.15 12.3 3.1 16 5.9 0.1 3.3 3 0 0 3 3 3 0 Fantastic Four meristem regulator CENP-K PF11802.8 CRK36074.1 - 0.31 10.6 3.2 0.24 10.9 1.3 1.7 1 1 0 1 1 1 0 Centromere-associated protein K Baculo_PEP_C PF04513.12 CRK36074.1 - 1.1 9.4 4.4 14 5.7 0.5 3.1 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus V-ATPase_G_2 PF16999.5 CRK36074.1 - 1.3 9.5 13.5 17 5.9 0.2 3.2 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit ApoLp-III PF07464.11 CRK36074.1 - 3.5 7.7 7.9 1.1 9.4 2.8 2.8 2 2 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) CdvA PF18822.1 CRK36074.1 - 4 7.3 19.8 0.3 10.9 0.6 3.4 3 1 0 3 3 3 0 CdvA-like coiled-coil domain SWIRM-assoc_2 PF16496.5 CRK36075.1 - 0.00083 18.3 0.5 0.0012 17.8 0.5 1.2 1 0 0 1 1 1 1 SWIRM-associated domain at the N-terminal HORMA PF02301.18 CRK36075.1 - 0.0018 17.9 0.0 0.0064 16.1 0.0 1.7 1 1 0 1 1 1 1 HORMA domain SUIM_assoc PF16619.5 CRK36075.1 - 0.0047 17.0 6.7 0.014 15.4 6.7 1.8 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 CRK36075.1 - 0.022 14.3 8.8 0.037 13.6 8.8 1.3 1 0 0 1 1 1 0 Spt20 family FAD_binding_4 PF01565.23 CRK36075.1 - 0.2 11.4 0.5 0.82 9.4 0.1 2.0 2 0 0 2 2 2 0 FAD binding domain DUF4834 PF16118.5 CRK36075.1 - 0.46 11.5 2.8 0.82 10.7 2.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Androgen_recep PF02166.16 CRK36075.1 - 0.84 8.4 12.6 0.011 14.6 5.2 1.7 2 0 0 2 2 2 0 Androgen receptor DUF4366 PF14283.6 CRK36075.1 - 1.4 9.0 3.5 0.72 9.9 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) PI31_Prot_N PF11566.8 CRK36076.1 - 2.6e-57 193.2 0.0 3.2e-57 192.9 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 CRK36076.1 - 4.3e-18 66.3 20.0 4.3e-18 66.3 20.0 3.2 3 1 0 3 3 3 1 PI31 proteasome regulator Sin_N PF04801.13 CRK36077.1 - 9.5e-22 77.8 0.1 2.8e-21 76.3 0.0 1.8 1 1 0 1 1 1 1 Sin-like protein conserved region PAT1 PF09770.9 CRK36078.1 - 0 1301.1 5.3 0 1301.0 5.3 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 T3SS_needle_F PF09392.10 CRK36078.1 - 0.091 13.0 0.2 0.31 11.3 0.2 1.9 1 0 0 1 1 1 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF NAM-associated PF14303.6 CRK36078.1 - 0.58 10.9 5.6 1.9 9.2 5.6 1.8 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain DUF4407 PF14362.6 CRK36078.1 - 6.4 6.0 9.5 0.89 8.8 3.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Glyco_transf_15 PF01793.16 CRK36079.1 - 1.4e-133 445.2 9.2 2.7e-133 444.2 9.2 1.4 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase PI31_Prot_N PF11566.8 CRK36079.1 - 9.4e-56 188.1 0.0 2.2e-55 186.9 0.0 1.7 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal Acyl-CoA_dh_1 PF00441.24 CRK36079.1 - 1.4e-40 138.9 2.2 3.6e-40 137.6 2.2 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CRK36079.1 - 1.8e-28 99.5 0.0 6.7e-28 97.6 0.0 2.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 CRK36079.1 - 1.5e-21 76.4 0.2 2.8e-21 75.5 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Sin_N PF04801.13 CRK36079.1 - 1.2e-20 74.2 0.0 3.1e-20 72.8 0.0 1.8 1 0 0 1 1 1 1 Sin-like protein conserved region Acyl-CoA_dh_2 PF08028.11 CRK36079.1 - 1.2e-16 61.2 0.1 1.2e-16 61.2 0.1 2.7 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 CRK36079.1 - 0.0034 17.1 0.0 0.0076 15.9 0.0 1.5 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal CdvA PF18822.1 CRK36079.1 - 0.17 11.7 13.0 0.3 10.9 0.7 2.6 2 0 0 2 2 2 0 CdvA-like coiled-coil domain DUF4404 PF14357.6 CRK36079.1 - 1.7 9.4 4.7 1.4 9.6 0.4 3.0 1 1 1 3 3 3 0 Domain of unknown function (DUF4404) ApoLp-III PF07464.11 CRK36079.1 - 2 8.5 6.2 1.6 8.8 2.3 2.8 2 1 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) CENP-K PF11802.8 CRK36079.1 - 2.2 7.8 5.0 0.55 9.8 1.2 1.7 1 1 1 2 2 2 0 Centromere-associated protein K Ribosom_S12_S23 PF00164.25 CRK36080.1 - 2e-28 98.3 0.9 2.6e-28 97.9 0.9 1.2 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Tli4_C PF18426.1 CRK36080.1 - 0.15 12.4 0.0 0.25 11.6 0.0 1.3 1 0 0 1 1 1 0 Tle cognate immunity protein 4 C-terminal domain SWIRM-assoc_2 PF16496.5 CRK36081.1 - 0.0054 15.7 0.1 0.008 15.1 0.1 1.2 1 0 0 1 1 1 1 SWIRM-associated domain at the N-terminal PAT1 PF09770.9 CRK36082.1 - 0 1303.7 4.7 0 1303.5 4.7 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 T3SS_needle_F PF09392.10 CRK36082.1 - 0.095 12.9 0.2 0.31 11.3 0.2 1.9 1 0 0 1 1 1 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF DUF4407 PF14362.6 CRK36082.1 - 8.2 5.7 8.9 0.7 9.2 2.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Glyco_transf_15 PF01793.16 CRK36083.1 - 7.7e-80 268.6 7.1 9.8e-80 268.2 7.1 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Ribosom_S12_S23 PF00164.25 CRK36084.1 - 2.1e-28 98.2 0.8 2.8e-28 97.8 0.8 1.2 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Tli4_C PF18426.1 CRK36084.1 - 0.15 12.4 0.0 0.25 11.6 0.0 1.3 1 0 0 1 1 1 0 Tle cognate immunity protein 4 C-terminal domain Acyl-CoA_dh_1 PF00441.24 CRK36085.1 - 2.1e-41 141.6 2.2 3.9e-41 140.7 2.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CRK36085.1 - 3.2e-29 101.9 0.0 8.7e-29 100.5 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 CRK36085.1 - 1.9e-22 79.3 0.2 3.9e-22 78.3 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 CRK36085.1 - 7.3e-18 65.1 0.1 1.4e-17 64.2 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 CRK36085.1 - 0.00036 20.3 0.0 0.0011 18.7 0.0 1.7 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Pkinase PF00069.25 CRK36086.1 - 3.2e-60 203.7 0.0 5.9e-60 202.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK36086.1 - 3.5e-35 121.5 0.0 6.1e-35 120.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.16 CRK36086.1 - 1.7e-24 85.7 20.0 9.4e-13 48.1 4.1 2.8 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.22 CRK36086.1 - 1.1e-19 70.0 31.8 6.3e-12 45.2 11.3 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 CRK36086.1 - 3.1e-14 53.4 1.0 1.2e-13 51.6 1.0 2.1 1 0 0 1 1 1 1 Protein kinase C terminal domain PAT1 PF09770.9 CRK36086.1 - 0.00019 19.9 13.4 0.00033 19.1 13.4 1.3 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 C2 PF00168.30 CRK36086.1 - 0.00024 21.3 0.0 0.0005 20.3 0.0 1.5 1 0 0 1 1 1 1 C2 domain Haspin_kinase PF12330.8 CRK36086.1 - 0.14 11.1 0.1 0.33 9.9 0.1 1.6 1 0 0 1 1 1 0 Haspin like kinase domain zf-RING_9 PF13901.6 CRK36086.1 - 0.95 9.4 23.1 0.69 9.9 8.1 2.5 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon She9_MDM33 PF05546.11 CRK36087.1 - 3.3e-49 167.4 6.4 4e-38 131.2 2.0 2.1 1 1 1 2 2 2 2 She9 / Mdm33 family Ndc1_Nup PF09531.10 CRK36087.1 - 0.0086 14.8 7.0 0.013 14.2 7.0 1.3 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup DUF3619 PF12279.8 CRK36087.1 - 0.01 16.2 2.3 0.022 15.1 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) PsbH PF00737.20 CRK36087.1 - 0.13 12.0 0.5 0.29 10.9 0.5 1.4 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein RE_SacI PF09566.10 CRK36087.1 - 0.14 12.0 0.0 0.21 11.3 0.0 1.2 1 0 0 1 1 1 0 SacI restriction endonuclease HAD PF12710.7 CRK36088.1 - 7.2e-21 75.4 0.0 9.9e-21 75.0 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CRK36088.1 - 0.00014 22.2 0.0 0.0071 16.7 0.0 2.7 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 CRK36088.1 - 0.00088 18.9 0.0 0.0021 17.6 0.0 1.6 2 0 0 2 2 2 1 Pyrimidine 5'-nucleotidase (UMPH-1) Put_Phosphatase PF06888.12 CRK36088.1 - 0.017 14.5 0.0 0.25 10.7 0.0 2.0 2 0 0 2 2 2 0 Putative Phosphatase MFS_1 PF07690.16 CRK36089.1 - 3.3e-20 72.3 67.3 1.8e-10 40.3 37.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily FdsD PF11390.8 CRK36089.1 - 0.047 14.0 0.0 0.81 10.1 0.0 2.6 3 0 0 3 3 3 0 NADH-dependant formate dehydrogenase delta subunit FdsD eIF-1a PF01176.19 CRK36090.1 - 1.3e-20 72.9 0.0 1.9e-20 72.4 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 ALG3 PF05208.13 CRK36091.1 - 1.6e-90 304.1 16.4 3.4e-65 220.8 5.1 2.1 1 1 1 2 2 2 2 ALG3 protein Thioredoxin PF00085.20 CRK36092.1 - 7.1e-26 90.2 0.1 9.1e-26 89.8 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 CRK36092.1 - 3e-05 24.4 0.4 0.00028 21.3 0.4 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CRK36092.1 - 4.3e-05 23.7 0.0 0.00022 21.5 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 CRK36092.1 - 7.3e-05 22.3 0.0 9.9e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 CRK36092.1 - 0.00048 20.0 0.0 0.00063 19.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CRK36092.1 - 0.0014 18.4 0.1 0.083 12.6 0.1 2.1 1 1 1 2 2 2 1 Redoxin Thioredoxin_9 PF14595.6 CRK36092.1 - 0.0016 18.2 0.0 0.002 17.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 CRK36092.1 - 0.0029 17.5 0.0 0.0035 17.2 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Glutaredoxin PF00462.24 CRK36092.1 - 0.11 12.7 0.1 0.3 11.3 0.1 1.8 2 1 0 2 2 2 0 Glutaredoxin Mg_trans_NIPA PF05653.14 CRK36093.1 - 4.9e-23 81.7 1.5 6.2e-23 81.3 1.5 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA PetL PF05115.14 CRK36093.1 - 0.023 14.7 1.4 0.051 13.5 1.4 1.6 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit VI (PetL) Mg_trans_NIPA PF05653.14 CRK36094.1 - 1.9e-65 220.9 15.4 2.2e-65 220.7 15.4 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 CRK36094.1 - 1.2e-05 25.6 5.7 1.2e-05 25.6 5.7 3.1 3 0 0 3 3 3 2 EamA-like transporter family SLC35F PF06027.12 CRK36094.1 - 0.0014 18.2 1.6 0.0014 18.2 1.6 1.8 2 0 0 2 2 2 1 Solute carrier family 35 PetL PF05115.14 CRK36094.1 - 4.5 7.3 10.3 0.15 12.1 1.3 2.8 2 0 0 2 2 2 0 Cytochrome B6-F complex subunit VI (PetL) Cu-oxidase_2 PF07731.14 CRK36095.1 - 5.3e-43 146.0 8.4 1.7e-39 134.7 0.9 3.1 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 CRK36095.1 - 6.1e-42 142.4 5.6 6.9e-40 135.8 0.9 3.4 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 CRK36095.1 - 3.5e-36 124.7 0.1 7.3e-33 113.9 0.0 2.4 2 0 0 2 2 2 2 Multicopper oxidase Cupredoxin_1 PF13473.6 CRK36095.1 - 0.0063 16.6 0.0 15 5.7 0.0 3.4 3 0 0 3 3 3 1 Cupredoxin-like domain MFS_1 PF07690.16 CRK36096.1 - 3.3e-35 121.6 26.0 1.6e-34 119.4 27.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily UPF0715 PF17094.5 CRK36096.1 - 1.1 9.8 5.4 0.44 11.1 0.3 2.7 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0715) Myb_DNA-bind_6 PF13921.6 CRK36097.1 - 3.8e-20 71.9 3.2 1.3e-10 41.4 0.1 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 CRK36097.1 - 6.4e-20 71.1 3.1 4.6e-11 42.7 0.1 2.8 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 CRK36097.1 - 0.0071 16.7 1.0 0.016 15.6 0.1 2.1 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain AAA_16 PF13191.6 CRK36098.1 - 6.6e-08 33.1 0.1 1.3e-07 32.1 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.13 CRK36098.1 - 0.0059 15.8 0.0 0.01 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 CRK36098.1 - 0.054 13.0 0.0 0.085 12.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_29 PF13555.6 CRK36098.1 - 0.061 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 CRK36098.1 - 0.16 12.0 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 CRK36098.1 - 0.18 12.2 0.1 0.57 10.6 0.1 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Fungal_trans_2 PF11951.8 CRK36099.1 - 1.1e-27 96.8 0.2 2.4e-16 59.5 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK36099.1 - 7e-09 35.7 12.5 1.4e-08 34.7 12.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AT_hook PF02178.19 CRK36099.1 - 0.2 11.6 5.8 0.59 10.2 5.8 1.8 1 0 0 1 1 1 0 AT hook motif Inhibitor_Mig-6 PF11555.8 CRK36099.1 - 3.7 7.7 19.2 0.28 11.3 11.8 2.5 2 0 0 2 2 2 0 EGFR receptor inhibitor Mig-6 PAPS_reduct PF01507.19 CRK36101.1 - 0.00022 21.3 0.0 0.00032 20.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Helicase_C PF00271.31 CRK36107.1 - 4.7e-30 104.2 0.1 1.8e-29 102.3 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Na_H_Exchanger PF00999.21 CRK36107.1 - 5.3e-18 65.0 4.9 7.5e-18 64.5 4.9 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DEAD PF00270.29 CRK36107.1 - 6e-05 22.9 0.1 0.00042 20.1 0.0 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase UTP25 PF06862.12 CRK36107.1 - 0.039 12.7 0.0 0.062 12.1 0.0 1.2 1 0 0 1 1 1 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DivIVA PF05103.13 CRK36107.1 - 0.066 13.3 17.8 0.035 14.2 13.0 2.4 1 1 1 2 2 2 0 DivIVA protein Fib_alpha PF08702.10 CRK36107.1 - 0.25 11.5 11.6 0.076 13.2 2.9 2.4 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Tropomyosin_1 PF12718.7 CRK36107.1 - 0.49 10.5 28.1 0.39 10.9 13.7 2.2 1 1 1 2 2 2 0 Tropomyosin like Tropomyosin PF00261.20 CRK36107.1 - 0.63 9.4 29.4 0.8 9.0 26.2 2.1 1 1 1 2 2 2 0 Tropomyosin CHD5 PF04420.14 CRK36107.1 - 0.88 9.4 6.0 0.83 9.5 2.8 2.2 1 1 1 2 2 2 0 CHD5-like protein CENP-F_leu_zip PF10473.9 CRK36107.1 - 1.4 8.9 28.3 1.8 8.6 12.5 2.4 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 CRK36107.1 - 1.4 8.9 5.9 0.76 9.8 0.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Fez1 PF06818.15 CRK36107.1 - 2.4 8.6 22.3 4 7.8 22.3 1.3 1 0 0 1 1 1 0 Fez1 SHE3 PF17078.5 CRK36107.1 - 2.4 7.8 15.0 2 8.1 7.7 2.3 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 DUF4472 PF14739.6 CRK36107.1 - 3.7 8.3 18.4 9.8 7.0 7.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4472) DUF4200 PF13863.6 CRK36107.1 - 3.8 8.0 22.8 0.88 10.0 10.8 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) PhaG_MnhG_YufB PF03334.14 CRK36107.1 - 4.7 7.5 12.4 3.4 8.0 0.2 3.7 3 1 0 3 3 3 0 Na+/H+ antiporter subunit Phage_GP20 PF06810.11 CRK36107.1 - 4.8 7.0 12.7 0.56 10.0 3.1 2.4 1 1 1 2 2 2 0 Phage minor structural protein GP20 ABC_tran_CTD PF16326.5 CRK36107.1 - 4.9 7.5 25.4 3.6 7.9 3.6 4.0 1 1 3 4 4 4 0 ABC transporter C-terminal domain DUF2457 PF10446.9 CRK36109.1 - 5.3 6.1 5.5 5.9 5.9 5.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) GSH_synth_ATP PF03917.17 CRK36110.1 - 1.3e-42 145.9 0.0 1.5e-42 145.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain X PF00739.19 CRK36114.1 - 1.4 9.1 7.9 1.3 9.2 7.9 1.0 1 0 0 1 1 1 0 Trans-activation protein X ERG2_Sigma1R PF04622.12 CRK36116.1 - 1.2e-38 132.6 0.0 1.3e-38 132.5 0.0 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein SAGA-Tad1 PF12767.7 CRK36117.1 - 3.2e-26 92.5 0.0 3.4e-26 92.4 0.0 1.0 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit OSCP PF00213.18 CRK36118.1 - 3e-20 73.1 0.1 3.2e-20 72.9 0.1 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Radical_SAM PF04055.21 CRK36119.1 - 1.4e-06 28.8 0.0 1.7e-06 28.5 0.0 1.1 1 0 0 1 1 1 1 Radical SAM superfamily DNA_pol_A_exo1 PF01612.20 CRK36121.1 - 1.1e-16 61.1 0.8 1.7e-12 47.4 0.0 2.2 2 0 0 2 2 2 2 3'-5' exonuclease HRDC PF00570.23 CRK36121.1 - 0.0054 16.7 0.1 0.0087 16.0 0.1 1.3 1 0 0 1 1 1 1 HRDC domain Gpi1 PF05024.15 CRK36122.1 - 4e-28 98.8 0.9 6.9e-28 98.0 0.5 1.6 2 0 0 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) Striatin PF08232.12 CRK36126.1 - 0.0016 19.1 5.9 0.0018 18.9 5.9 1.2 1 0 0 1 1 1 1 Striatin family Tho2 PF11262.8 CRK36126.1 - 0.021 14.1 7.7 0.021 14.1 7.7 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF3450 PF11932.8 CRK36126.1 - 0.035 13.4 12.8 0.042 13.2 12.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) HAUS-augmin3 PF14932.6 CRK36126.1 - 0.1 12.2 10.4 0.11 12.0 10.4 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF1730 PF08331.10 CRK36126.1 - 0.16 11.9 2.4 0.21 11.5 2.4 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1730) APG6_N PF17675.1 CRK36126.1 - 0.25 11.9 11.9 0.35 11.4 11.9 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region UPF0242 PF06785.11 CRK36126.1 - 0.46 10.6 10.9 0.53 10.4 10.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4407 PF14362.6 CRK36126.1 - 1.3 8.3 10.3 1.8 7.9 10.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ADIP PF11559.8 CRK36126.1 - 3.6 7.6 15.9 3.3 7.8 10.2 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Bud13 PF09736.9 CRK36126.1 - 6.9 7.1 10.8 9.9 6.5 10.8 1.3 1 1 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex DUF4140 PF13600.6 CRK36126.1 - 8.7 6.9 14.1 0.38 11.2 6.2 1.9 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Nic96 PF04097.14 CRK36127.1 - 3.5e-22 78.6 0.0 3.9e-22 78.5 0.0 1.0 1 0 0 1 1 1 1 Nup93/Nic96 Vezatin PF12632.7 CRK36128.1 - 2.6e-22 79.5 0.1 2.8e-22 79.4 0.1 1.0 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes Cyclin_N PF00134.23 CRK36129.1 - 3.4e-38 130.3 0.0 3.1e-37 127.2 0.0 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CRK36129.1 - 2.8e-33 114.5 0.0 4.7e-33 113.8 0.0 1.3 1 0 0 1 1 1 1 Cyclin, C-terminal domain HEPN_Toprim_N PF18871.1 CRK36129.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 HEPN/Toprim N-terminal domain 1 QWRF PF04484.12 CRK36131.1 - 4.5 6.9 8.8 4.7 6.9 8.8 1.1 1 0 0 1 1 1 0 QWRF family tRNA_lig_CPD PF08302.11 CRK36139.1 - 5.3e-19 68.7 0.4 9.6e-19 67.8 0.4 1.4 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain Prot_ATP_ID_OB PF16450.5 CRK36139.1 - 1.8e-18 66.2 0.1 3.3e-18 65.4 0.1 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain RNA_lig_T4_1 PF09511.10 CRK36139.1 - 5.4e-17 62.4 0.0 1e-16 61.5 0.0 1.5 1 0 0 1 1 1 1 RNA ligase RPN2_C PF18004.1 CRK36139.1 - 2.7 7.9 10.9 6.6 6.6 10.9 1.6 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Phage_holin_4_1 PF05105.12 CRK36140.1 - 0.033 14.3 0.2 0.044 13.9 0.2 1.3 1 1 0 1 1 1 0 Bacteriophage holin family CPSase_L_D2 PF02786.17 CRK36141.1 - 1.1e-24 87.2 0.0 1.2e-24 87.1 0.0 1.0 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.22 CRK36141.1 - 0.00028 20.5 0.0 0.0003 20.4 0.0 1.0 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 CRK36141.1 - 0.0024 17.4 0.0 0.0028 17.2 0.0 1.2 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus RimK PF08443.11 CRK36141.1 - 0.03 13.9 0.0 0.036 13.7 0.0 1.1 1 0 0 1 1 1 0 RimK-like ATP-grasp domain IMPa_N_2 PF18650.1 CRK36143.1 - 0.15 11.3 0.0 0.17 11.1 0.0 1.0 1 0 0 1 1 1 0 Immunomodulating metalloprotease N-terminal domain Chromo PF00385.24 CRK36146.1 - 1.4e-05 24.9 4.7 0.0032 17.3 2.1 2.3 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain DUF743 PF05332.11 CRK36148.1 - 0.085 12.9 0.4 0.16 12.0 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF743) FTHFS PF01268.19 CRK36149.1 - 4.7e-62 210.0 0.2 5.2e-62 209.8 0.2 1.0 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase MAF_flag10 PF01973.18 CRK36149.1 - 0.092 12.4 0.0 0.28 10.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function DUF115 EAP30 PF04157.16 CRK36150.1 - 1.1e-11 44.5 0.1 1.3e-11 44.3 0.1 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Alpha-E PF04168.12 CRK36152.1 - 0.065 13.0 0.1 0.075 12.8 0.1 1.1 1 0 0 1 1 1 0 A predicted alpha-helical domain with a conserved ER motif. TFIIF_alpha PF05793.12 CRK36154.1 - 0.011 14.4 3.2 0.011 14.3 3.2 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CwsA PF10814.8 CRK36155.1 - 0.06 13.5 0.1 0.086 13.0 0.1 1.3 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA GDA1_CD39 PF01150.17 CRK36156.1 - 1.5e-27 96.4 0.0 1.6e-27 96.3 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Glyco_hydro_47 PF01532.20 CRK36158.1 - 4e-24 85.3 0.0 4.3e-24 85.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Proteasome PF00227.26 CRK36163.1 - 3.7e-29 101.6 0.0 7.1e-14 51.7 0.0 2.0 2 0 0 2 2 2 2 Proteasome subunit GTP1_OBG PF01018.22 CRK36165.1 - 1.1e-13 51.1 2.4 1.1e-13 51.0 2.4 1.0 1 0 0 1 1 1 1 GTP1/OBG Rrf2 PF02082.20 CRK36165.1 - 0.045 14.1 0.1 0.059 13.7 0.1 1.2 1 0 0 1 1 1 0 Transcriptional regulator HgmA PF04209.13 CRK36166.1 - 3.2e-62 210.6 1.5 3.5e-62 210.5 1.5 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase UQ_con PF00179.26 CRK36169.1 - 1.8e-35 121.6 0.2 2e-35 121.5 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CRK36169.1 - 0.0091 15.7 0.0 0.01 15.5 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B Neugrin PF06413.11 CRK36174.1 - 1.7 8.6 8.3 2.3 8.2 0.9 2.2 1 1 1 2 2 2 0 Neugrin Amino_oxidase PF01593.24 CRK36175.1 - 4.5e-42 144.9 0.1 8.7e-42 143.9 0.1 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CRK36175.1 - 5.3e-07 29.8 0.1 2.4e-06 27.7 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain RRM_1 PF00076.22 CRK36176.1 - 5.4e-09 35.8 0.2 1.8e-08 34.1 0.1 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CRK36176.1 - 2.2e-05 24.3 0.0 4.6e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 CRK36176.1 - 0.007 16.2 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_3 PF08777.11 CRK36176.1 - 0.06 13.4 0.5 0.11 12.5 0.1 1.7 2 0 0 2 2 2 0 RNA binding motif MFS_1 PF07690.16 CRK36177.1 - 1.6e-19 70.1 67.7 7.7e-13 48.1 26.0 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily Cutinase PF01083.22 CRK36178.1 - 1.6e-46 158.5 0.0 2.1e-46 158.1 0.0 1.1 1 0 0 1 1 1 1 Cutinase VirJ PF06057.11 CRK36178.1 - 0.011 15.6 0.0 0.015 15.1 0.0 1.1 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) DUF3089 PF11288.8 CRK36178.1 - 0.19 11.2 0.0 0.29 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) adh_short_C2 PF13561.6 CRK36179.1 - 9.5e-53 179.1 4.7 1.2e-52 178.9 4.7 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRK36179.1 - 5.9e-40 136.8 1.1 7.2e-40 136.5 1.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CRK36179.1 - 4.9e-13 49.4 1.1 8e-13 48.7 1.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CRK36179.1 - 2.3e-07 30.5 0.3 4.4e-07 29.6 0.3 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CRK36179.1 - 0.0094 15.4 0.0 0.026 13.9 0.0 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase ABC2_membrane PF01061.24 CRK36180.1 - 3.1e-67 226.1 57.4 2e-38 131.9 21.3 3.5 3 1 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 CRK36180.1 - 4e-35 121.3 0.0 4.1e-16 59.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 CRK36180.1 - 5.1e-29 100.0 0.7 8.1e-25 86.6 0.0 3.3 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 CRK36180.1 - 5.2e-18 65.5 0.2 1.8e-17 63.7 0.1 2.1 2 0 0 2 2 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 CRK36180.1 - 6.3e-07 28.8 39.1 0.00039 19.6 17.1 2.7 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.6 CRK36180.1 - 9.1e-07 29.4 0.1 0.0084 16.5 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 CRK36180.1 - 9.7e-07 28.9 0.0 0.053 13.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 CRK36180.1 - 5.2e-06 26.7 3.0 0.024 14.8 0.1 3.3 3 1 0 3 3 2 2 AAA domain AAA_18 PF13238.6 CRK36180.1 - 3.6e-05 24.3 0.0 0.023 15.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CRK36180.1 - 0.00014 21.5 0.2 0.012 15.4 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CRK36180.1 - 0.0003 20.7 0.1 0.0031 17.4 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_17 PF13207.6 CRK36180.1 - 0.00097 19.6 0.2 0.27 11.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CRK36180.1 - 0.0018 18.5 0.2 0.2 11.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 CRK36180.1 - 0.0018 17.9 0.1 0.042 13.4 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 CRK36180.1 - 0.0057 16.9 0.1 0.14 12.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 CRK36180.1 - 0.0092 15.4 0.0 0.76 9.2 0.0 2.9 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 CRK36180.1 - 0.019 14.7 0.3 1.6 8.4 0.1 2.4 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 CRK36180.1 - 0.031 13.9 2.1 0.63 9.6 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 CRK36180.1 - 0.1 12.6 0.3 6.8 6.7 0.1 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 CRK36180.1 - 0.11 12.9 0.3 15 6.0 0.0 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 CRK36180.1 - 0.12 12.8 0.2 0.42 11.1 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_24 PF13479.6 CRK36180.1 - 0.14 11.8 0.6 13 5.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 CRK36180.1 - 0.15 11.8 0.7 10 5.8 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 CRK36180.1 - 0.15 11.9 6.1 3.4 7.6 0.0 2.7 3 0 0 3 3 2 0 NACHT domain DUF3073 PF11273.8 CRK36180.1 - 0.19 12.5 1.3 0.59 10.9 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3073) AAA_19 PF13245.6 CRK36180.1 - 0.21 11.9 0.9 6.4 7.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 CRK36180.1 - 0.21 11.7 1.0 18 5.5 0.2 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF4834 PF16118.5 CRK36180.1 - 0.27 12.2 0.7 2.1 9.4 0.0 2.9 2 0 0 2 2 1 0 Domain of unknown function (DUF4834) RCC1 PF00415.18 CRK36182.1 - 6.5e-65 215.6 0.4 5.9e-12 46.0 0.0 7.7 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CRK36182.1 - 2.3e-41 138.8 20.2 1e-08 34.7 0.0 6.8 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Yip1 PF04893.17 CRK36184.1 - 3e-05 23.8 17.7 0.0054 16.5 11.5 2.7 2 1 0 2 2 2 2 Yip1 domain uDENN PF03456.18 CRK36184.1 - 0.12 13.2 0.0 0.21 12.3 0.0 1.4 1 0 0 1 1 1 0 uDENN domain NmrA PF05368.13 CRK36185.1 - 2.3e-26 92.8 0.0 1e-25 90.7 0.0 1.8 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 CRK36185.1 - 4.2e-12 46.3 2.2 6.3e-11 42.5 2.1 2.1 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 CRK36185.1 - 0.00065 19.7 0.1 0.0014 18.6 0.1 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CRK36185.1 - 0.0028 17.1 0.0 0.0052 16.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 CRK36185.1 - 0.014 14.6 0.0 0.037 13.2 0.0 1.6 1 1 0 1 1 1 0 Male sterility protein GDP_Man_Dehyd PF16363.5 CRK36185.1 - 0.017 14.6 0.0 0.023 14.1 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 CRK36185.1 - 0.029 13.4 0.0 0.086 11.8 0.0 1.7 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 CRK36185.1 - 0.084 13.0 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Stig1 PF04885.13 CRK36186.1 - 5.3e-08 33.4 39.1 2.2e-05 25.0 14.2 13.4 1 1 14 16 16 16 2 Stigma-specific protein, Stig1 Beta_helix PF13229.6 CRK36187.1 - 2e-10 40.8 23.1 7.9e-09 35.6 10.7 3.3 1 1 2 3 3 3 3 Right handed beta helix region Chondroitinas_B PF14592.6 CRK36187.1 - 3.7e-07 29.4 0.0 2e-06 27.0 0.0 2.1 2 0 0 2 2 2 1 Chondroitinase B DUF1565 PF07602.11 CRK36187.1 - 0.014 14.7 6.2 0.019 14.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1565) Pam16 PF03656.13 CRK36188.1 - 4.7e-32 110.7 0.1 5.6e-32 110.4 0.1 1.0 1 0 0 1 1 1 1 Pam16 Ribosomal_L22 PF00237.19 CRK36188.1 - 0.12 12.7 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L22p/L17e BPL_N PF09825.9 CRK36190.1 - 7.9e-141 469.5 0.0 1e-140 469.2 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 CRK36190.1 - 4.1e-18 65.5 0.0 6.6e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family ThuA PF06283.11 CRK36190.1 - 0.12 12.6 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Trehalose utilisation CHCH PF06747.13 CRK36191.1 - 0.01 15.9 4.7 0.027 14.6 4.7 1.7 1 1 0 1 1 1 0 CHCH domain CX9C PF16860.5 CRK36191.1 - 0.19 11.8 2.1 0.33 11.0 0.6 1.9 1 1 1 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, TB2_DP1_HVA22 PF03134.19 CRK36192.1 - 1.4e-26 92.2 9.3 2.3e-26 91.5 9.3 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family zf-C2H2_4 PF13894.6 CRK36193.1 - 1.5e-05 25.4 15.8 0.086 13.7 0.0 4.8 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.26 CRK36193.1 - 0.032 14.7 15.0 0.4 11.2 0.1 4.0 3 0 0 3 3 3 0 Zinc finger, C2H2 type Prok-RING_4 PF14447.6 CRK36193.1 - 0.66 9.9 5.7 0.43 10.5 1.8 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C2H2_jaz PF12171.8 CRK36193.1 - 1.2 9.5 0.0 1.2 9.5 0.0 3.3 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Glyco_hydro_31 PF01055.26 CRK36194.1 - 5.9e-91 305.9 7.2 9.7e-91 305.1 7.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF4968 PF16338.5 CRK36194.1 - 6.7e-07 29.5 0.0 1.6e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4968) MFS_1 PF07690.16 CRK36195.1 - 2.4e-53 181.3 91.4 1.3e-30 106.5 29.6 2.4 2 0 0 2 2 2 2 Major Facilitator Superfamily Sigma70_ner PF04546.13 CRK36196.1 - 0.0033 17.3 4.9 0.0033 17.3 4.9 2.0 2 0 0 2 2 2 1 Sigma-70, non-essential region DUF2951 PF11166.8 CRK36196.1 - 0.012 15.8 4.2 0.012 15.8 4.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2951) HBM PF16591.5 CRK36196.1 - 0.017 14.6 8.4 0.021 14.3 6.9 1.9 1 1 0 1 1 1 0 Helical bimodular sensor domain EDR1 PF14381.6 CRK36196.1 - 0.018 14.8 2.8 0.033 13.9 1.8 1.8 1 1 1 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 DUF501 PF04417.12 CRK36196.1 - 0.037 13.8 2.6 0.062 13.1 2.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF501) DUF632 PF04782.12 CRK36196.1 - 0.043 13.1 9.2 0.056 12.8 9.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF632) Peptidase_M9_N PF08453.10 CRK36196.1 - 0.096 12.4 0.4 0.14 11.9 0.4 1.3 1 0 0 1 1 1 0 Peptidase family M9 N-terminal DivIC PF04977.15 CRK36196.1 - 0.45 10.3 18.0 0.52 10.1 0.4 3.7 2 1 2 4 4 4 0 Septum formation initiator Csm1_N PF18504.1 CRK36196.1 - 0.61 10.5 14.2 0.29 11.5 0.5 3.3 3 0 0 3 3 3 0 Csm1 N-terminal domain TEX13 PF15186.6 CRK36196.1 - 1.8 8.2 10.5 0.41 10.3 6.4 2.0 1 1 0 1 1 1 0 Testis-expressed sequence 13 protein family V_ATPase_I PF01496.19 CRK36196.1 - 2 6.3 6.0 2.3 6.0 6.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1664 PF07889.12 CRK36196.1 - 2.9 7.9 9.2 2.5 8.1 0.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FapA PF03961.13 CRK36196.1 - 6.1 5.3 11.4 17 3.9 11.5 1.6 1 1 0 1 1 1 0 Flagellar Assembly Protein A GPI-anchored PF10342.9 CRK36197.1 - 0.011 16.5 0.1 0.017 15.9 0.1 1.3 1 0 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Pellino PF04710.14 CRK36197.1 - 0.085 11.5 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Pellino FtsJ PF01728.19 CRK36198.1 - 1.8e-10 41.2 0.0 2.6e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Peptidase_M35 PF02102.15 CRK36202.1 - 7.2e-79 265.3 9.3 8.6e-79 265.0 9.3 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 CRK36202.1 - 6.9e-44 149.9 3.6 6.9e-44 149.9 3.6 1.7 2 0 0 2 2 2 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.6 CRK36202.1 - 0.015 14.9 5.7 0.024 14.2 5.7 1.4 1 1 0 1 1 1 0 Putative peptidase family GAF_2 PF13185.6 CRK36204.1 - 7.4e-12 45.7 0.2 9.8e-12 45.3 0.2 1.1 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 CRK36204.1 - 3.9e-05 24.3 0.1 4.6e-05 24.1 0.1 1.1 1 0 0 1 1 1 1 GAF domain MFS_1 PF07690.16 CRK36205.1 - 3.3e-29 101.9 50.5 8.8e-25 87.4 29.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Frag1 PF10277.9 CRK36205.1 - 0.0038 16.8 0.2 0.0075 15.8 0.2 1.5 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Arylsulfotran_2 PF14269.6 CRK36207.1 - 3.9e-61 207.0 0.2 5.1e-61 206.7 0.2 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 CRK36207.1 - 2.2e-12 46.6 0.0 2.9e-11 42.9 0.0 2.2 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Fungal_trans PF04082.18 CRK36211.1 - 3.7e-23 81.9 0.3 6.6e-23 81.1 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Mannosidase_ig PF17786.1 CRK36211.1 - 7.1e-17 61.8 0.1 1.6e-16 60.7 0.1 1.6 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Zn_clus PF00172.18 CRK36211.1 - 3.8e-06 26.9 13.9 1e-05 25.5 13.9 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_2 PF00703.21 CRK36211.1 - 1.5e-05 25.6 0.0 4.4e-05 24.1 0.0 1.9 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Ig_mannosidase PF17753.1 CRK36211.1 - 9.1e-05 22.1 0.0 0.00042 20.0 0.0 2.1 2 0 0 2 2 2 1 Ig-fold domain Glyco_hydro_2_C PF02836.17 CRK36211.1 - 0.001 18.2 0.0 0.0022 17.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain FMN_dh PF01070.18 CRK36213.1 - 1.4e-98 330.2 0.1 3.6e-98 328.8 0.1 1.6 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 CRK36213.1 - 6.4e-17 61.5 0.0 1.2e-16 60.6 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 CRK36213.1 - 1.2e-05 24.7 0.1 2e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 CRK36213.1 - 4.4e-05 22.6 0.2 0.00011 21.3 0.1 1.6 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 CRK36213.1 - 0.014 14.8 0.2 0.023 14.1 0.2 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase ThiG PF05690.14 CRK36213.1 - 0.033 13.5 0.0 1 8.6 0.2 2.3 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 CRK36213.1 - 0.11 11.9 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein Dimerisation2 PF16864.5 CRK36213.1 - 0.18 11.8 0.0 0.7 9.9 0.0 2.0 2 0 0 2 2 2 0 Dimerisation domain Retrotran_gag_3 PF14244.6 CRK36216.1 - 0.0076 16.0 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Sugar_tr PF00083.24 CRK36218.1 - 5.1e-94 315.7 23.0 5.9e-94 315.5 23.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK36218.1 - 3.2e-32 111.8 21.7 3.2e-32 111.8 21.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Peptidase_S10 PF00450.22 CRK36219.1 - 1.7e-71 241.9 0.0 2.6e-71 241.3 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase Fapy_DNA_glyco PF01149.24 CRK36219.1 - 8.5e-34 116.7 0.0 2e-33 115.4 0.0 1.6 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 CRK36219.1 - 3.3e-21 75.1 0.0 6.9e-21 74.0 0.0 1.5 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.11 CRK36219.1 - 0.0013 17.6 0.0 0.0035 16.2 0.0 1.6 2 0 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) Ribosomal_S13 PF00416.22 CRK36219.1 - 0.026 14.9 0.0 0.051 14.0 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S13/S18 Bac_rhamnosid_C PF17390.2 CRK36219.1 - 0.093 12.5 0.0 0.5 10.2 0.0 2.2 2 0 0 2 2 2 0 Bacterial alpha-L-rhamnosidase C-terminal domain Cupin_2 PF07883.11 CRK36223.1 - 3.7e-11 42.6 0.1 1e-10 41.2 0.1 1.7 1 1 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 CRK36223.1 - 1.6e-06 27.8 0.1 2.9e-06 27.0 0.1 1.3 1 0 0 1 1 1 1 Cupin PAS_9 PF13426.7 CRK36223.1 - 5e-06 26.7 0.0 9.8e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 PAS domain SLD5_C PF16922.5 CRK36223.1 - 0.0054 16.9 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus zf-Nse PF11789.8 CRK36224.1 - 4.2e-16 58.5 0.6 7.5e-16 57.7 0.6 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 CRK36224.1 - 7.1e-06 26.0 0.6 1.2e-05 25.3 0.6 1.3 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 CRK36224.1 - 0.021 15.1 0.9 0.037 14.3 0.9 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CRK36224.1 - 0.035 14.5 1.0 0.055 13.8 1.0 1.3 1 0 0 1 1 1 0 Ring finger domain Zn_ribbon_17 PF17120.5 CRK36224.1 - 0.061 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 CRK36224.1 - 0.11 12.4 0.3 0.19 11.6 0.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-MIZ PF02891.20 CRK36224.1 - 0.17 11.6 0.5 0.31 10.8 0.5 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Hexokinase_2 PF03727.16 CRK36225.1 - 2.4e-54 184.3 0.0 4e-54 183.6 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 CRK36225.1 - 4.3e-42 144.3 0.0 7e-42 143.6 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Glucosamine_iso PF01182.20 CRK36227.1 - 4.3e-21 75.8 0.0 7.3e-21 75.1 0.0 1.3 1 1 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase NDT80_PhoG PF05224.12 CRK36228.1 - 2e-30 106.4 0.0 3.5e-30 105.6 0.0 1.4 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Amidohydro_1 PF01979.20 CRK36228.1 - 1.1e-09 38.0 0.0 1.9e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 CRK36228.1 - 6.9e-07 29.1 0.0 1.1e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Glyco_hydro_3 PF00933.21 CRK36229.1 - 8.2e-52 176.6 0.0 1.2e-51 176.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_1 PF00583.25 CRK36229.1 - 7.8e-06 26.1 0.0 0.00012 22.3 0.0 2.6 3 0 0 3 3 3 1 Acetyltransferase (GNAT) family Glyco_hydro_3_C PF01915.22 CRK36229.1 - 0.0015 18.5 0.0 0.0029 17.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_7 PF13508.7 CRK36229.1 - 0.024 15.1 0.0 0.13 12.7 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CRK36229.1 - 0.066 13.2 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyco_hydro_31 PF01055.26 CRK36232.1 - 1.8e-107 360.3 1.3 1.8e-107 360.3 1.3 1.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 CRK36232.1 - 3.7e-14 52.8 0.1 2.5e-13 50.1 0.0 2.4 2 0 0 2 2 2 1 Galactose mutarotase-like Glyco_hydro_3 PF00933.21 CRK36233.1 - 0.00024 20.6 0.0 0.0003 20.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3 PF00933.21 CRK36234.1 - 3.1e-54 184.5 0.0 4e-54 184.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyoxalase PF00903.25 CRK36234.1 - 3.8e-20 72.4 0.0 1.5e-19 70.5 0.0 2.0 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 CRK36234.1 - 1.5e-05 25.2 0.0 3.5e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 CRK36234.1 - 0.0017 19.1 0.0 0.0035 18.1 0.0 1.5 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_2 PF12681.7 CRK36234.1 - 0.019 14.9 0.0 0.09 12.7 0.0 2.0 1 1 0 1 1 1 0 Glyoxalase-like domain Glyco_hydro_3_C PF01915.22 CRK36235.1 - 6.7e-50 169.9 0.0 1e-49 169.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 CRK36235.1 - 2.1e-47 162.0 0.0 3.3e-47 161.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 CRK36235.1 - 1.1e-22 79.9 0.1 2.8e-22 78.6 0.1 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain CARDB PF07705.11 CRK36235.1 - 0.0017 18.6 0.2 0.0044 17.2 0.2 1.6 1 0 0 1 1 1 1 CARDB Mur_ligase_C PF02875.21 CRK36235.1 - 0.041 14.1 0.0 0.25 11.6 0.0 2.1 2 0 0 2 2 2 0 Mur ligase family, glutamate ligase domain GBS_Bsp-like PF08481.10 CRK36235.1 - 0.072 13.2 0.5 0.64 10.2 0.1 2.5 2 0 0 2 2 2 0 GBS Bsp-like repeat Sugar-bind PF04198.13 CRK36235.1 - 0.097 11.8 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Putative sugar-binding domain Glyco_hydro_31 PF01055.26 CRK36236.1 - 3e-107 359.5 1.4 4.4e-107 359.0 1.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 CRK36236.1 - 3.7e-14 52.8 0.1 2.5e-13 50.1 0.0 2.4 2 0 0 2 2 2 1 Galactose mutarotase-like bZIP_2 PF07716.15 CRK36238.1 - 0.00023 21.2 15.2 0.00033 20.7 15.2 1.2 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 CRK36238.1 - 0.00072 19.6 12.7 0.001 19.1 12.7 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 CRK36238.1 - 0.0023 18.4 8.4 0.0035 17.8 8.4 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor Takusan PF04822.13 CRK36238.1 - 0.0079 16.1 2.9 0.014 15.3 2.9 1.4 1 0 0 1 1 1 1 Takusan MCC-bdg_PDZ PF10506.9 CRK36238.1 - 0.02 14.9 0.6 0.032 14.3 0.6 1.3 1 0 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome VIR_N PF15912.5 CRK36238.1 - 1.1 8.8 7.3 1.7 8.2 7.3 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal UCH PF00443.29 CRK36239.1 - 1.8e-24 86.6 5.4 1.1e-14 54.6 0.0 2.8 2 1 1 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CRK36239.1 - 9.8e-13 48.4 3.4 3.1e-07 30.3 0.0 2.6 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Tachykinin PF02202.16 CRK36239.1 - 0.047 13.6 2.2 13 6.0 0.2 3.0 2 0 0 2 2 2 0 Tachykinin family DUF5427 PF10310.9 CRK36239.1 - 0.11 11.4 13.6 0.19 10.6 13.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Macoilin PF09726.9 CRK36239.1 - 0.34 9.4 13.0 0.46 9.0 13.0 1.1 1 0 0 1 1 1 0 Macoilin family Asp-B-Hydro_N PF05279.11 CRK36239.1 - 1.2 9.1 16.0 0.045 13.8 10.1 1.6 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region Yos1 PF08571.10 CRK36240.1 - 1.3e-35 121.5 1.2 1.5e-35 121.3 1.2 1.0 1 0 0 1 1 1 1 Yos1-like Glyco_transf_22 PF03901.17 CRK36241.1 - 1e-46 160.0 16.0 7e-39 134.2 12.0 2.1 1 1 1 2 2 2 2 Alg9-like mannosyltransferase family MetallophosN PF16371.5 CRK36241.1 - 0.006 16.8 0.1 6 7.2 0.0 2.3 2 0 0 2 2 2 2 N terminal of Calcineurin-like phosphoesterase Zn_clus PF00172.18 CRK36243.1 - 0.0019 18.3 6.9 0.0045 17.1 6.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ubiquitin PF00240.23 CRK36244.1 - 5.4e-102 333.6 13.3 1.9e-33 114.0 0.6 3.0 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.8 CRK36244.1 - 1.3e-48 162.7 13.8 1.2e-15 57.1 0.7 3.0 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CRK36244.1 - 7.5e-18 64.8 6.1 0.00026 21.4 0.1 4.6 3 3 0 3 3 3 3 Ubiquitin-like domain Ubiquitin_5 PF18037.1 CRK36244.1 - 1.6e-12 47.6 2.3 0.014 15.7 0.1 3.1 1 1 2 3 3 3 3 Ubiquitin-like domain TBK1_ULD PF18396.1 CRK36244.1 - 1.7e-12 47.1 1.7 0.016 15.1 0.1 3.2 3 0 0 3 3 3 3 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 CRK36244.1 - 4.7e-11 42.8 1.3 0.073 13.2 0.0 3.9 3 3 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 CRK36244.1 - 7.2e-10 39.4 0.3 0.21 12.1 0.0 3.2 1 1 1 3 3 3 3 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 CRK36244.1 - 1.7e-08 34.4 0.3 0.3 10.9 0.0 3.1 1 1 2 3 3 3 3 Silencing defective 2 N-terminal ubiquitin domain Ubiquitin_4 PF18036.1 CRK36244.1 - 2.4e-06 27.5 16.0 11 6.1 0.2 6.0 6 0 0 6 6 6 0 Ubiquitin-like domain DUF3861 PF12977.7 CRK36244.1 - 8.5e-05 22.7 1.0 8 6.7 0.0 3.2 3 0 0 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3861) ACT_5 PF13710.6 CRK36244.1 - 0.00015 21.5 2.1 6.9 6.6 0.0 3.3 3 0 0 3 3 3 0 ACT domain DUF2870 PF11069.8 CRK36244.1 - 0.00027 21.2 0.0 20 5.6 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2870) Methyltrans_RNA PF04452.14 CRK36244.1 - 0.00058 19.3 0.1 1.1 8.5 0.0 2.4 2 0 0 2 2 2 2 RNA methyltransferase Big_7 PF17957.1 CRK36244.1 - 0.0011 19.6 0.1 34 5.3 0.0 3.2 3 0 0 3 3 3 0 Bacterial Ig domain YcgR_2 PF12945.7 CRK36244.1 - 0.003 17.7 2.9 19 5.5 0.1 3.3 3 0 0 3 3 3 0 Flagellar protein YcgR UDP-g_GGTase PF06427.11 CRK36244.1 - 0.0069 16.5 3.0 4.5 7.4 0.0 3.1 4 0 0 4 4 3 2 UDP-glucose:Glycoprotein Glucosyltransferase DUF969 PF06149.12 CRK36244.1 - 0.0076 15.7 0.0 15 5.0 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF969) DUF493 PF04359.14 CRK36244.1 - 0.031 14.9 0.0 95 3.7 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF493) Raf1_HTH PF18579.1 CRK36244.1 - 0.031 14.0 0.0 71 3.2 0.0 3.2 3 0 0 3 3 3 0 Rubisco accumulation factor 1 helix turn helix domain ACT_4 PF13291.6 CRK36244.1 - 0.032 14.8 0.3 96 3.7 0.0 3.3 3 0 0 3 3 3 0 ACT domain ORF11CD3 PF10549.9 CRK36244.1 - 0.088 12.9 0.0 62 3.8 0.0 3.4 3 0 0 3 3 3 0 ORF11CD3 domain ProRS-C_2 PF09181.10 CRK36244.1 - 0.12 12.5 2.6 72 3.6 0.1 3.2 3 0 0 3 3 3 0 Prolyl-tRNA synthetase, C-terminal Tash_PEST PF07708.11 CRK36244.1 - 0.13 12.4 18.4 4.5 7.6 1.4 3.3 3 0 0 3 3 3 0 Tash protein PEST motif Myosin_N PF02736.19 CRK36244.1 - 0.27 11.1 3.4 76 3.3 0.0 4.3 3 0 0 3 3 3 0 Myosin N-terminal SH3-like domain DMA PF03474.14 CRK36244.1 - 0.44 10.2 1.7 1.1e+02 2.5 0.0 3.2 3 0 0 3 3 3 0 DMRTA motif Plexin_cytopl PF08337.12 CRK36244.1 - 0.53 8.9 10.5 8.3 4.9 0.4 3.9 2 1 1 4 4 4 0 Plexin cytoplasmic RasGAP domain PI3K_p85B PF02192.16 CRK36244.1 - 0.85 9.4 5.0 67 3.3 0.1 3.3 3 0 0 3 3 3 0 PI3-kinase family, p85-binding domain FlgD_ig PF13860.6 CRK36244.1 - 2.8 7.9 4.9 1.2e+02 2.6 0.1 3.3 3 0 0 3 3 3 0 FlgD Ig-like domain BRAP2 PF07576.12 CRK36245.1 - 1.6e-21 76.4 0.0 3.1e-21 75.4 0.0 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 CRK36245.1 - 1.3e-17 63.8 4.1 1.3e-17 63.8 4.1 2.7 3 0 0 3 3 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 CRK36245.1 - 4.9e-08 33.2 9.8 4.9e-08 33.2 9.8 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 CRK36245.1 - 3.6e-07 29.8 5.2 1.4e-06 27.9 5.2 2.1 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 CRK36245.1 - 1.7e-06 27.7 10.2 4.1e-06 26.5 10.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CRK36245.1 - 2e-05 24.3 8.5 5.3e-05 23.0 8.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CRK36245.1 - 4.4e-05 23.3 7.9 4.4e-05 23.3 7.9 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CRK36245.1 - 0.00022 21.1 9.4 0.00022 21.1 9.4 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 CRK36245.1 - 0.00049 20.3 7.8 0.0016 18.7 7.8 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 CRK36245.1 - 0.00062 19.6 7.5 0.00062 19.6 7.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CRK36245.1 - 0.00065 19.7 3.2 0.00065 19.7 3.2 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_6 PF14835.6 CRK36245.1 - 0.0058 16.5 3.6 0.0058 16.5 3.6 1.7 2 0 0 2 2 2 1 zf-RING of BARD1-type protein DUF4616 PF15394.6 CRK36245.1 - 0.035 13.1 5.6 0.053 12.5 5.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4616) zf-C3HC4_4 PF15227.6 CRK36245.1 - 0.36 11.0 3.9 4.5 7.5 4.4 2.5 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 CRK36245.1 - 0.43 10.7 7.3 1.2 9.2 7.3 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger GldM_N PF12081.8 CRK36245.1 - 0.79 9.8 9.2 1.3 9.0 9.2 1.3 1 0 0 1 1 1 0 GldM N-terminal domain YabA PF06156.13 CRK36245.1 - 1.4 9.6 11.2 1.9 9.1 3.1 2.4 2 0 0 2 2 2 0 Initiation control protein YabA zf-UBP_var PF17807.1 CRK36245.1 - 4.7 7.0 7.0 1.4 8.8 0.2 2.9 3 0 0 3 3 3 0 Variant UBP zinc finger PhzC-PhzF PF02567.16 CRK36246.1 - 5e-38 131.2 0.0 6.4e-38 130.8 0.0 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Ank_2 PF12796.7 CRK36247.1 - 6.1e-28 97.2 0.2 2e-09 37.9 0.0 4.3 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CRK36247.1 - 1.3e-23 83.1 2.0 6.8e-07 29.7 0.0 5.8 3 1 3 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CRK36247.1 - 1.5e-20 71.1 7.7 1.2e-05 25.3 0.0 7.8 8 0 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.6 CRK36247.1 - 1.5e-18 66.6 4.4 7.6e-06 26.1 0.1 4.8 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 CRK36247.1 - 4.3e-14 52.2 4.0 4.6e-05 23.7 0.1 5.5 5 1 0 5 5 5 4 Ankyrin repeat Chromo_shadow PF01393.19 CRK36248.1 - 5.7e-23 80.8 2.3 4.9e-18 65.0 0.2 2.3 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.24 CRK36248.1 - 1.8e-15 56.6 0.6 1.8e-15 56.6 0.6 2.2 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain DUF4944 PF16302.5 CRK36248.1 - 0.0019 18.3 0.9 0.1 12.7 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4944) DUF4449 PF14613.6 CRK36248.1 - 0.037 14.1 0.1 0.073 13.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4449) DUF2968 PF11180.8 CRK36249.1 - 0.0072 16.0 8.2 0.014 15.0 8.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2968) RNA_polI_A14 PF08203.11 CRK36249.1 - 0.082 13.6 0.3 0.23 12.2 0.3 1.8 1 0 0 1 1 1 0 Yeast RNA polymerase I subunit RPA14 Kre28 PF17097.5 CRK36249.1 - 0.14 11.1 3.8 0.21 10.5 3.8 1.2 1 0 0 1 1 1 0 Spindle pole body component DUF4407 PF14362.6 CRK36249.1 - 0.18 11.1 4.2 0.034 13.5 1.0 1.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Chibby PF14645.6 CRK36249.1 - 0.2 12.1 5.0 0.15 12.5 2.6 1.8 1 1 0 2 2 2 0 Chibby family YabA PF06156.13 CRK36249.1 - 0.27 11.9 3.1 0.31 11.7 1.1 2.0 2 0 0 2 2 2 0 Initiation control protein YabA YlqD PF11068.8 CRK36249.1 - 0.35 11.2 5.8 0.79 10.1 5.8 1.6 1 0 0 1 1 1 0 YlqD protein HALZ PF02183.18 CRK36249.1 - 0.53 10.5 5.5 4.6 7.5 4.2 2.8 3 0 0 3 3 3 0 Homeobox associated leucine zipper bZIP_1 PF00170.21 CRK36249.1 - 0.84 9.8 9.9 0.048 13.8 4.2 1.8 2 0 0 2 2 2 0 bZIP transcription factor Atg14 PF10186.9 CRK36249.1 - 1.4 7.9 7.5 2.4 7.2 7.5 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Nnf1 PF03980.14 CRK36249.1 - 2.6 8.5 9.3 3.8 7.9 4.8 2.5 2 0 0 2 2 2 0 Nnf1 DivIC PF04977.15 CRK36249.1 - 8 6.3 11.7 0.098 12.4 3.6 1.9 2 0 0 2 2 2 0 Septum formation initiator Chromo PF00385.24 CRK36250.1 - 7.2e-16 57.8 0.6 1.8e-15 56.5 0.6 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 CRK36250.1 - 0.0067 16.5 0.2 0.013 15.6 0.2 1.5 1 0 0 1 1 1 1 Chromo shadow domain DUF4449 PF14613.6 CRK36250.1 - 0.032 14.4 0.1 0.069 13.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4449) VID27_N PF17748.1 CRK36250.1 - 0.29 11.0 3.2 0.42 10.4 3.2 1.2 1 0 0 1 1 1 0 VID27 N-terminal region Hydrophob_seed PF14547.6 CRK36250.1 - 0.45 10.8 4.8 0.71 10.1 4.8 1.3 1 0 0 1 1 1 0 Hydrophobic seed protein zf-Di19 PF05605.12 CRK36252.1 - 0.02 15.2 0.1 0.047 14.0 0.1 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 CRK36252.1 - 0.036 14.9 0.1 0.1 13.5 0.1 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 CRK36252.1 - 0.038 13.9 0.0 0.069 13.1 0.0 1.4 1 0 0 1 1 1 0 zinc-finger of a C2HC-type Atg14 PF10186.9 CRK36252.1 - 0.047 12.8 2.5 0.077 12.1 2.5 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 zf-C2H2 PF00096.26 CRK36252.1 - 0.085 13.4 0.1 0.2 12.2 0.1 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type Chibby PF14645.6 CRK36252.1 - 0.094 13.1 3.8 0.36 11.3 3.8 2.0 1 1 0 1 1 1 0 Chibby family Kre28 PF17097.5 CRK36252.1 - 0.14 11.1 3.1 0.22 10.4 3.1 1.2 1 0 0 1 1 1 0 Spindle pole body component YlqD PF11068.8 CRK36252.1 - 0.29 11.5 5.0 0.76 10.1 5.0 1.7 1 0 0 1 1 1 0 YlqD protein DUF4407 PF14362.6 CRK36252.1 - 0.69 9.2 9.3 0.015 14.6 1.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) HALZ PF02183.18 CRK36252.1 - 1.6 9.0 5.7 7 7.0 4.2 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper bZIP_1 PF00170.21 CRK36252.1 - 2.7 8.2 10.7 0.074 13.2 4.2 1.7 2 0 0 2 2 2 0 bZIP transcription factor DUF2968 PF11180.8 CRK36252.1 - 3.3 7.3 14.6 0.034 13.8 6.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) DivIC PF04977.15 CRK36252.1 - 7.9 6.3 10.9 0.15 11.8 3.6 1.9 2 0 0 2 2 2 0 Septum formation initiator Putative_PNPOx PF01243.20 CRK36253.1 - 4e-08 33.3 0.0 0.00033 20.8 0.0 2.6 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase NAD_binding_1 PF00175.21 CRK36253.1 - 0.0048 17.5 0.0 0.0082 16.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Pkinase PF00069.25 CRK36254.1 - 0.00052 19.5 0.0 0.1 12.0 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain DUF3246 PF11596.8 CRK36256.1 - 0.032 13.7 1.4 7 6.0 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) SKIP_SNW PF02731.15 CRK36256.1 - 0.041 13.6 7.8 1.8 8.2 1.0 2.7 2 0 0 2 2 2 0 SKIP/SNW domain Pyr_redox_2 PF07992.14 CRK36257.1 - 1.3e-17 64.0 0.6 1.7e-17 63.6 0.6 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 CRK36257.1 - 5.4e-14 51.9 18.7 7e-14 51.5 18.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 CRK36257.1 - 4.6e-06 25.5 5.2 5.4e-06 25.2 5.2 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein Sugar_tr PF00083.24 CRK36257.1 - 8.3e-06 24.9 4.8 8.3e-06 24.9 4.8 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter NAD_binding_9 PF13454.6 CRK36257.1 - 0.033 14.2 2.3 0.043 13.8 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding DUF3042 PF11240.8 CRK36257.1 - 0.27 11.3 1.7 0.79 9.8 1.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) DAO PF01266.24 CRK36257.1 - 0.41 10.2 0.0 0.41 10.2 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase HgmA PF04209.13 CRK36258.1 - 2.6e-168 560.1 0.0 3.1e-168 559.9 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Sugar_tr PF00083.24 CRK36261.1 - 9.2e-11 41.3 0.6 1e-10 41.1 0.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK36261.1 - 0.00094 18.2 1.1 0.0012 17.9 1.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Ribosomal_L27A PF00828.19 CRK36262.1 - 0.001 19.7 2.0 0.001 19.7 2.0 1.5 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 2OG-FeII_Oxy_3 PF13640.6 CRK36263.1 - 8.7e-05 23.3 0.0 0.00011 23.1 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Imm70 PF15601.6 CRK36263.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 70 BAR PF03114.18 CRK36268.1 - 2.8e-15 56.6 0.7 2.8e-15 56.6 0.7 1.3 2 0 0 2 2 2 1 BAR domain DUF4143 PF13635.6 CRK36271.1 - 0.061 13.5 0.0 0.079 13.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4143) MARVEL PF01284.23 CRK36277.1 - 9.3e-06 25.7 7.0 9.9e-06 25.6 7.0 1.1 1 0 0 1 1 1 1 Membrane-associating domain CbiQ PF02361.16 CRK36277.1 - 0.3 10.7 6.9 0.31 10.6 6.9 1.0 1 0 0 1 1 1 0 Cobalt transport protein 2TM PF13239.6 CRK36277.1 - 0.38 11.1 6.0 0.49 10.7 6.0 1.3 1 0 0 1 1 1 0 2TM domain Wzy_C PF04932.15 CRK36277.1 - 0.39 10.3 4.4 0.43 10.2 4.4 1.1 1 0 0 1 1 1 0 O-Antigen ligase LMBR1 PF04791.16 CRK36277.1 - 0.74 8.7 6.0 0.7 8.7 6.0 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF485 PF04341.12 CRK36277.1 - 2.1 8.3 12.0 3.2 7.8 12.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF485 AvrPtoB-E3_ubiq PF09046.10 CRK36279.1 - 0.17 12.2 0.0 0.19 12.0 0.0 1.2 1 0 0 1 1 1 0 AvrPtoB E3 ubiquitin ligase SUR7 PF06687.12 CRK36280.1 - 0.017 14.7 0.0 0.02 14.6 0.0 1.0 1 0 0 1 1 1 0 SUR7/PalI family SIR2 PF02146.17 CRK36281.1 - 3.6e-08 33.5 0.0 5.8e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.13 CRK36281.1 - 0.034 13.9 0.0 0.06 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF592) GMC_oxred_C PF05199.13 CRK36285.1 - 2.4e-11 44.4 0.0 2.8e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GED PF02212.18 CRK36289.1 - 1e-31 108.9 1.5 1.1e-31 108.8 1.5 1.0 1 0 0 1 1 1 1 Dynamin GTPase effector domain Piwi PF02171.17 CRK36293.1 - 2.5e-21 76.2 0.0 3.1e-21 75.9 0.0 1.1 1 0 0 1 1 1 1 Piwi domain Ras PF00071.22 CRK36297.1 - 2.2e-25 89.1 0.0 2.5e-25 89.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CRK36297.1 - 5.3e-12 46.0 0.0 7e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 CRK36297.1 - 0.0011 19.0 0.0 0.0013 18.8 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 CRK36297.1 - 0.0054 16.2 0.0 0.0058 16.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CRK36297.1 - 0.016 14.7 0.1 0.21 11.1 0.1 2.0 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain PRK PF00485.18 CRK36297.1 - 0.024 14.4 0.0 0.028 14.2 0.0 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.12 CRK36297.1 - 0.13 11.6 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Zeta toxin G-alpha PF00503.20 CRK36297.1 - 0.16 11.1 0.0 0.93 8.6 0.0 1.9 1 1 1 2 2 2 0 G-protein alpha subunit NB-ARC PF00931.22 CRK36297.1 - 0.19 10.9 0.0 0.22 10.7 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain SUIM_assoc PF16619.5 CRK36297.1 - 2.9 8.0 7.1 5.4 7.2 7.1 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 GARS_A PF01071.19 CRK36302.1 - 7.6e-36 123.7 0.0 8.4e-36 123.6 0.0 1.0 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Cucumopine_C PF18631.1 CRK36302.1 - 0.1 12.5 0.0 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 Cucumopine synthase C-terminal helical bundle domain Sec7 PF01369.20 CRK36309.1 - 1.6e-26 93.1 0.2 1.8e-26 93.0 0.2 1.0 1 0 0 1 1 1 1 Sec7 domain DnaJ PF00226.31 CRK36313.1 - 1.8e-22 79.2 1.7 3e-22 78.5 1.7 1.4 1 0 0 1 1 1 1 DnaJ domain VAPB_antitox PF02697.14 CRK36313.1 - 0.11 13.3 0.4 9.5 7.1 0.2 2.2 1 1 1 2 2 2 0 Putative antitoxin Trehalase PF01204.18 CRK36316.1 - 1.7e-10 40.4 0.0 1.7e-10 40.4 0.0 1.0 1 0 0 1 1 1 1 Trehalase RFX5_N PF18326.1 CRK36316.1 - 0.16 11.8 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 RFX5 N-terminal domain Hydrolase PF00702.26 CRK36319.1 - 1.5e-05 25.4 0.0 1.8e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase SMK-1 PF04802.15 CRK36326.1 - 2.6e-32 112.2 0.0 3e-32 112.0 0.0 1.0 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 ABC_tran PF00005.27 CRK36329.1 - 6.8e-06 26.6 0.0 8.8e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_23 PF13476.6 CRK36329.1 - 2.6e-05 24.8 0.0 4.3e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 CRK36329.1 - 0.00069 18.8 0.0 0.00072 18.7 0.0 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_25 PF13481.6 CRK36329.1 - 0.009 15.6 0.0 0.012 15.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 CRK36329.1 - 0.01 15.6 0.1 0.023 14.5 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 CRK36329.1 - 0.014 14.7 0.8 0.025 13.9 0.4 1.6 1 1 1 2 2 2 0 FtsK/SpoIIIE family RsgA_GTPase PF03193.16 CRK36329.1 - 0.015 15.2 0.2 0.026 14.4 0.1 1.4 1 1 1 2 2 2 0 RsgA GTPase SMC_N PF02463.19 CRK36329.1 - 0.016 14.7 0.0 0.02 14.3 0.0 1.1 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Adeno_IVa2 PF02456.15 CRK36329.1 - 0.044 12.6 0.0 0.05 12.4 0.0 1.1 1 0 0 1 1 1 0 Adenovirus IVa2 protein cobW PF02492.19 CRK36329.1 - 0.054 13.1 0.2 0.074 12.6 0.2 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.6 CRK36329.1 - 0.067 13.0 0.1 0.096 12.5 0.1 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 CRK36329.1 - 0.075 12.7 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain ResIII PF04851.15 CRK36329.1 - 0.098 12.7 0.0 0.098 12.7 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DnaB_C PF03796.15 CRK36329.1 - 0.12 11.7 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Dynamin_N PF00350.23 CRK36329.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Dynamin family AAA_11 PF13086.6 CRK36329.1 - 0.14 11.9 0.0 0.17 11.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 CRK36329.1 - 0.16 11.2 0.0 0.21 10.9 0.0 1.1 1 0 0 1 1 1 0 Zeta toxin TrwB_AAD_bind PF10412.9 CRK36329.1 - 0.17 10.8 0.1 0.21 10.5 0.1 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.6 CRK36329.1 - 0.18 11.5 0.1 0.24 11.1 0.1 1.1 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 CRK36329.1 - 0.23 10.9 0.1 0.33 10.4 0.1 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 CRK36329.1 - 0.24 10.9 0.0 0.33 10.5 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region Asp PF00026.23 CRK36333.1 - 2.8e-22 79.6 0.4 3.3e-22 79.3 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CRK36333.1 - 4.3e-11 43.4 0.6 2.5e-09 37.6 0.6 2.1 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 CRK36333.1 - 0.013 16.1 0.0 0.61 10.8 0.0 2.1 1 1 0 1 1 1 0 Aspartyl protease DAHP_synth_1 PF00793.20 CRK36337.1 - 9.3e-11 41.1 0.1 1e-10 40.9 0.1 1.2 1 0 0 1 1 1 1 DAHP synthetase I family DUF1013 PF06242.11 CRK36337.1 - 0.014 15.4 0.0 0.015 15.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1013) IATP PF04568.12 CRK36339.1 - 0.21 12.0 4.2 1.7 9.1 0.2 2.5 2 1 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP DUF3080 PF11279.8 CRK36346.1 - 0.019 14.2 0.2 0.021 14.1 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3080) Cytochrom_B562 PF07361.11 CRK36346.1 - 0.024 15.3 1.5 0.09 13.4 1.4 2.0 1 1 0 1 1 1 0 Cytochrome b562 TPR_10 PF13374.6 CRK36346.1 - 0.038 13.9 0.9 0.52 10.2 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TYW3 PF02676.14 CRK36346.1 - 0.12 11.7 0.2 0.21 10.9 0.2 1.4 1 0 0 1 1 1 0 Methyltransferase TYW3 DUF3498 PF12004.8 CRK36346.1 - 0.15 11.2 1.8 0.16 11.2 1.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) KELK PF15796.5 CRK36346.1 - 2.4 8.7 8.8 1.5 9.3 0.3 2.5 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Chromate_transp PF02417.15 CRK36350.1 - 8e-13 48.8 5.1 8.4e-13 48.7 5.1 1.0 1 0 0 1 1 1 1 Chromate transporter Transket_pyr PF02779.24 CRK36355.1 - 9.7e-20 71.0 0.6 1e-19 70.9 0.6 1.0 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain AcetylCoA_hydro PF02550.15 CRK36358.1 - 3.9e-12 46.6 0.1 4.3e-12 46.4 0.1 1.0 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain ANAPC4_WD40 PF12894.7 CRK36374.1 - 4.6e-12 46.1 0.0 0.018 15.3 0.0 4.1 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CRK36374.1 - 7.8e-11 42.4 1.5 0.15 13.0 0.0 5.3 6 0 0 6 6 6 4 WD domain, G-beta repeat Gmad1 PF10647.9 CRK36374.1 - 1.7e-05 24.7 2.8 3.4e-05 23.7 0.7 2.2 1 1 1 2 2 2 1 Lipoprotein LpqB beta-propeller domain VID27 PF08553.10 CRK36374.1 - 0.0033 16.5 0.0 0.0048 16.0 0.0 1.2 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain Coatomer_WDAD PF04053.14 CRK36374.1 - 0.004 16.3 0.0 0.13 11.2 0.0 2.0 1 1 0 1 1 1 1 Coatomer WD associated region Lactonase PF10282.9 CRK36374.1 - 0.0087 15.4 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller HPS3_N PF14761.6 CRK36374.1 - 0.054 13.0 0.0 1.4 8.4 0.0 2.5 1 1 2 3 3 3 0 Hermansky-Pudlak syndrome 3 Frtz PF11768.8 CRK36374.1 - 0.061 11.6 0.0 0.16 10.3 0.0 1.5 1 1 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Sun2_CC2 PF18580.1 CRK36374.1 - 0.18 12.1 0.0 0.51 10.6 0.0 1.8 1 0 0 1 1 1 0 SUN2 coiled coil domain 2 CN_hydrolase PF00795.22 CRK36386.1 - 0.00074 18.9 0.0 0.00097 18.5 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DUF3658 PF12395.8 CRK36386.1 - 0.16 11.9 0.0 0.2 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function Hist_deacetyl PF00850.19 CRK36390.1 - 1.1e-30 107.2 0.2 1.2e-30 107.1 0.2 1.0 1 0 0 1 1 1 1 Histone deacetylase domain AA_permease_2 PF13520.6 CRK36394.1 - 0.00011 21.2 5.1 0.00012 21.0 5.1 1.0 1 0 0 1 1 1 1 Amino acid permease Pkinase_C PF00433.24 CRK36395.1 - 2.7e-08 34.4 1.1 4.9e-08 33.6 1.1 1.4 1 0 0 1 1 1 1 Protein kinase C terminal domain AMP-binding PF00501.28 CRK36397.1 - 1.6e-10 40.2 0.7 1.8e-10 40.0 0.2 1.3 2 0 0 2 2 2 1 AMP-binding enzyme TGT PF01702.18 CRK36398.1 - 3.4e-76 256.7 0.0 4.1e-76 256.4 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Ribul_P_3_epim PF00834.19 CRK36399.1 - 2e-20 73.1 0.1 2.3e-20 72.8 0.1 1.1 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family ThiG PF05690.14 CRK36399.1 - 0.0013 18.1 0.0 0.0014 18.0 0.0 1.0 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG OMPdecase PF00215.24 CRK36399.1 - 0.0065 16.1 0.1 0.0072 15.9 0.1 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family QRPTase_C PF01729.19 CRK36399.1 - 0.057 13.2 0.0 0.065 13.0 0.0 1.1 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain MAS20 PF02064.15 CRK36400.1 - 0.077 13.1 0.3 0.099 12.7 0.3 1.1 1 0 0 1 1 1 0 MAS20 protein import receptor GCP_C_terminal PF04130.13 CRK36418.1 - 1e-48 166.4 0.0 7.7e-48 163.5 0.0 2.1 3 0 0 3 3 3 1 Gamma tubulin complex component C-terminal DASH_Ask1 PF08655.10 CRK36418.1 - 1.3e-27 95.5 0.1 2.4e-27 94.6 0.1 1.4 1 0 0 1 1 1 1 DASH complex subunit Ask1 Rhodanese PF00581.20 CRK36418.1 - 5e-10 39.9 0.0 9.7e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain GCP_N_terminal PF17681.1 CRK36418.1 - 9.4e-07 28.7 0.0 2.1e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal Eaf7 PF07904.13 CRK36419.1 - 4.8e-26 91.2 0.1 4.8e-26 91.2 0.1 2.4 2 1 0 2 2 2 1 Chromatin modification-related protein EAF7 API5 PF05918.11 CRK36419.1 - 0.38 9.5 12.6 0.56 9.0 12.6 1.4 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) NOA36 PF06524.12 CRK36419.1 - 0.66 9.2 14.5 1.1 8.5 14.5 1.3 1 0 0 1 1 1 0 NOA36 protein CNDH2_C PF16858.5 CRK36419.1 - 0.76 9.6 10.6 1.5 8.7 10.6 1.4 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term LAP1C PF05609.12 CRK36419.1 - 1.1 8.3 13.5 1.6 7.7 13.5 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Nucleo_P87 PF07267.11 CRK36419.1 - 1.3 7.7 11.1 1.7 7.4 11.1 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Mitofilin PF09731.9 CRK36419.1 - 1.9 7.2 19.8 2.4 6.9 19.8 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Nop14 PF04147.12 CRK36419.1 - 2.5 6.2 22.5 3.7 5.6 22.5 1.1 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.11 CRK36419.1 - 3.1 7.3 20.8 4.4 6.8 20.8 1.3 1 0 0 1 1 1 0 PPP4R2 CDC27 PF09507.10 CRK36419.1 - 7.1 5.9 33.3 0.12 11.7 26.1 1.6 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 MMS1_N PF10433.9 CRK36420.1 - 1.2e-60 205.6 0.0 3.6e-60 204.0 0.0 1.7 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term GTP_EFTU PF00009.27 CRK36420.1 - 5e-35 120.8 0.0 1e-34 119.8 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 CRK36420.1 - 4.4e-09 36.6 0.3 1.3e-08 35.0 0.3 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CRK36420.1 - 5.7e-06 26.4 0.0 1.5e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 CRK36420.1 - 0.00063 19.9 0.0 0.0029 17.8 0.0 2.2 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 CRK36420.1 - 0.02 14.7 0.0 0.038 13.8 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Ras PF00071.22 CRK36420.1 - 0.15 11.6 0.0 0.54 9.8 0.0 2.0 1 1 0 1 1 1 0 Ras family Cwf_Cwc_15 PF04889.12 CRK36420.1 - 0.47 10.1 40.4 0.85 9.3 40.4 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Dynamin_N PF00350.23 CRK36420.1 - 1.8 8.6 4.1 0.4 10.7 0.1 1.9 2 0 0 2 2 2 0 Dynamin family SDA1 PF05285.12 CRK36420.1 - 4.5 6.6 38.9 7.2 5.9 38.9 1.2 1 0 0 1 1 1 0 SDA1 Ndc1_Nup PF09531.10 CRK36420.1 - 8 5.0 5.8 13 4.4 5.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TPR_2 PF07719.17 CRK36421.1 - 1.7e-10 40.2 5.2 0.00015 21.6 0.1 5.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 CRK36421.1 - 3e-07 30.0 0.9 0.0077 16.0 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 CRK36421.1 - 0.00011 22.0 9.5 0.18 11.9 0.2 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 CRK36421.1 - 0.013 16.1 20.2 0.024 15.3 1.1 5.9 5 1 0 5 5 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 CRK36421.1 - 0.018 15.1 0.9 0.13 12.4 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 CRK36421.1 - 0.02 15.0 0.1 9.4 6.7 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 CRK36421.1 - 0.038 14.6 0.3 0.038 14.6 0.3 6.4 7 1 1 8 8 8 0 Tetratricopeptide repeat TPR_14 PF13428.6 CRK36421.1 - 0.041 14.7 20.7 0.32 11.9 1.0 6.2 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_11 PF13414.6 CRK36421.1 - 0.069 12.9 0.7 1.7 8.4 0.0 3.6 4 0 0 4 4 4 0 TPR repeat TPR_19 PF14559.6 CRK36421.1 - 0.31 11.6 10.0 0.44 11.1 0.1 4.1 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 CRK36421.1 - 0.48 10.7 13.9 2.2 8.6 2.3 5.1 5 1 0 5 5 4 0 Tetratricopeptide repeat HSP70 PF00012.20 CRK36422.1 - 1.8e-165 551.6 3.5 1.8e-165 551.6 3.5 2.1 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 CRK36422.1 - 1.5e-14 53.6 0.0 1.5e-13 50.3 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 CRK36422.1 - 8.5e-05 22.9 0.7 0.18 12.2 0.1 4.0 3 1 0 3 3 3 2 Cell division protein FtsA Trans_reg_C PF00486.28 CRK36422.1 - 0.11 12.5 0.0 0.4 10.8 0.0 1.9 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal Apolipoprotein PF01442.18 CRK36422.1 - 3.4 7.5 19.2 2.6 7.9 16.5 2.1 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain MIF4G PF02854.19 CRK36423.1 - 1.2e-58 198.2 0.0 1.8e-29 102.9 0.0 3.7 3 1 0 3 3 3 3 MIF4G domain Upf2 PF04050.14 CRK36423.1 - 1e-41 142.8 5.3 1e-41 142.8 5.3 2.4 3 0 0 3 3 3 1 Up-frameshift suppressor 2 DUF1896 PF08989.10 CRK36423.1 - 0.62 10.2 3.3 24 5.0 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1896) Mo-co_dimer PF03404.16 CRK36424.1 - 5.6e-61 204.6 0.1 1.1e-60 203.7 0.1 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain FAD_binding_6 PF00970.24 CRK36424.1 - 1.2e-33 115.3 0.0 2.2e-33 114.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 CRK36424.1 - 4.4e-27 94.9 0.0 8.9e-27 93.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 CRK36424.1 - 3.8e-20 71.8 0.0 8e-20 70.8 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Oxidored_molyb PF00174.19 CRK36424.1 - 1.4e-13 50.8 0.8 4.9e-08 32.8 0.3 2.4 1 1 1 2 2 2 2 Oxidoreductase molybdopterin binding domain NAD_binding_6 PF08030.12 CRK36424.1 - 0.0024 18.0 0.0 0.018 15.1 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Nucleopor_Nup85 PF07575.13 CRK36425.1 - 0.34 9.4 0.3 0.53 8.8 0.3 1.2 1 0 0 1 1 1 0 Nup85 Nucleoporin BCDHK_Adom3 PF10436.9 CRK36426.1 - 8.7e-13 48.4 0.1 1.5e-12 47.6 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase Yip1 PF04893.17 CRK36426.1 - 1.7e-10 40.9 13.5 3.1e-10 40.1 13.5 1.3 1 0 0 1 1 1 1 Yip1 domain Inhibitor_I9 PF05922.16 CRK36426.1 - 7.3e-10 39.4 0.4 2.6e-09 37.6 0.4 1.9 1 0 0 1 1 1 1 Peptidase inhibitor I9 Ran_BP1 PF00638.18 CRK36426.1 - 2e-08 34.5 0.1 0.0078 16.5 0.0 2.6 2 0 0 2 2 2 2 RanBP1 domain Glyco_hydro_75 PF07335.11 CRK36426.1 - 0.0021 18.3 0.2 0.012 15.9 0.0 2.3 2 0 0 2 2 2 1 Fungal chitosanase of glycosyl hydrolase group 75 HATPase_c PF02518.26 CRK36426.1 - 0.046 14.2 0.0 0.24 11.9 0.0 2.3 2 1 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1282 PF06930.12 CRK36426.1 - 0.11 12.3 6.0 0.18 11.6 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) RIBIOP_C PF04950.12 CRK36427.1 - 1.7e-91 306.7 0.0 1.7e-91 306.7 0.0 2.4 3 0 0 3 3 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 CRK36427.1 - 2.7e-27 94.7 0.0 1e-26 92.8 0.0 2.1 1 0 0 1 1 1 1 AARP2CN (NUC121) domain AAA_22 PF13401.6 CRK36427.1 - 1.1e-05 25.7 0.0 3.2e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CRK36427.1 - 7.1e-05 23.2 0.0 0.00024 21.5 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 CRK36427.1 - 0.00026 21.4 0.0 0.00069 20.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 CRK36427.1 - 0.00061 19.9 0.0 0.0023 18.0 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 CRK36427.1 - 0.00068 20.2 1.0 0.0051 17.3 0.0 2.6 2 0 0 2 2 2 1 ABC transporter RNA_helicase PF00910.22 CRK36427.1 - 0.0017 18.8 0.0 0.0041 17.5 0.0 1.7 1 0 0 1 1 1 1 RNA helicase NB-ARC PF00931.22 CRK36427.1 - 0.0017 17.6 0.1 0.0054 16.0 0.0 1.8 2 0 0 2 2 2 1 NB-ARC domain GTP_EFTU PF00009.27 CRK36427.1 - 0.0018 17.9 1.0 0.86 9.1 0.0 2.9 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain NACHT PF05729.12 CRK36427.1 - 0.0023 17.9 0.0 0.0056 16.6 0.0 1.7 1 1 0 1 1 1 1 NACHT domain AAA_33 PF13671.6 CRK36427.1 - 0.0026 17.9 0.9 0.0082 16.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain Ploopntkinase3 PF18751.1 CRK36427.1 - 0.0039 17.1 0.0 0.0097 15.8 0.0 1.7 1 0 0 1 1 1 1 P-loop Nucleotide Kinase3 AAA_18 PF13238.6 CRK36427.1 - 0.0049 17.4 1.4 0.038 14.6 0.0 3.3 3 0 0 3 3 2 1 AAA domain AAA_14 PF13173.6 CRK36427.1 - 0.0054 16.8 0.0 0.014 15.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CRK36427.1 - 0.0091 16.3 0.0 0.028 14.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CRK36427.1 - 0.011 15.4 0.0 0.011 15.4 0.0 1.9 2 0 0 2 2 1 0 AAA domain Rad17 PF03215.15 CRK36427.1 - 0.013 15.5 0.0 0.15 12.0 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain PduV-EutP PF10662.9 CRK36427.1 - 0.017 14.9 0.0 0.062 13.1 0.0 1.8 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 CRK36427.1 - 0.022 14.4 0.0 0.048 13.3 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 CRK36427.1 - 0.029 13.9 0.1 0.11 11.9 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region ATPase_2 PF01637.18 CRK36427.1 - 0.031 14.2 0.0 0.031 14.2 0.0 2.0 2 0 0 2 2 1 0 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 CRK36427.1 - 0.032 14.2 0.0 0.13 12.1 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase NTPase_1 PF03266.15 CRK36427.1 - 0.044 13.7 0.1 0.098 12.6 0.1 1.6 1 0 0 1 1 1 0 NTPase Roc PF08477.13 CRK36427.1 - 0.046 13.9 0.0 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase MobB PF03205.14 CRK36427.1 - 0.098 12.6 1.5 0.35 10.8 0.0 2.5 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.14 CRK36427.1 - 0.13 12.3 2.3 0.17 11.9 0.0 2.4 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.17 CRK36427.1 - 0.17 11.7 0.3 0.65 9.7 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_17 PF13207.6 CRK36427.1 - 0.39 11.1 0.0 0.39 11.1 0.0 3.9 4 0 0 4 4 3 0 AAA domain TFIIA_gamma_C PF02751.14 CRK36428.1 - 1.4e-24 86.0 0.9 2.3e-24 85.3 0.9 1.4 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.16 CRK36428.1 - 3.1e-22 78.3 0.5 4.1e-22 77.9 0.5 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain ATP-synt_C PF00137.21 CRK36429.1 - 4.2e-24 84.6 24.8 5.9e-14 52.2 9.5 4.2 4 0 0 4 4 4 2 ATP synthase subunit C SLATT_5 PF18160.1 CRK36429.1 - 0.9 8.8 4.0 0.32 10.3 0.1 2.0 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 MoeA_N PF03453.17 CRK36430.1 - 6.6e-33 113.7 1.6 1.5e-32 112.5 1.6 1.6 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.24 CRK36430.1 - 2e-23 82.6 0.2 4.9e-23 81.4 0.2 1.7 1 0 0 1 1 1 1 Probable molybdopterin binding domain MoeA_C PF03454.15 CRK36430.1 - 3.8e-17 62.2 0.0 1.4e-16 60.4 0.0 2.0 2 0 0 2 2 2 1 MoeA C-terminal region (domain IV) zf-RING_5 PF14634.6 CRK36430.1 - 1.3e-07 31.5 6.3 2.1e-07 30.8 6.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CRK36430.1 - 0.0006 19.8 0.9 0.0014 18.6 0.9 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 CRK36430.1 - 0.0014 18.4 2.4 0.0032 17.3 2.4 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 CRK36430.1 - 0.0028 17.9 5.6 0.0054 17.0 5.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CRK36430.1 - 0.0045 16.8 5.2 0.0085 15.9 5.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CRK36430.1 - 0.0068 16.2 4.8 0.013 15.3 4.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CRK36430.1 - 0.017 14.9 5.5 0.03 14.2 5.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Mito_carr PF00153.27 CRK36430.1 - 0.081 12.9 0.0 0.39 10.7 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial carrier protein DUF2096 PF09869.9 CRK36430.1 - 0.13 12.3 0.9 0.31 11.1 0.9 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2096) BLOC1_2 PF10046.9 CRK36430.1 - 0.25 11.6 4.1 0.26 11.6 1.0 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 zf-C3HC4_4 PF15227.6 CRK36430.1 - 0.78 9.9 2.7 1.8 8.8 2.7 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-MIZ PF02891.20 CRK36430.1 - 2.2 8.1 4.3 4.2 7.2 4.3 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zinc-ribbons_6 PF07191.12 CRK36430.1 - 5.9 7.0 7.1 18 5.4 3.6 2.4 2 0 0 2 2 2 0 zinc-ribbons Fungal_trans PF04082.18 CRK36432.1 - 8.1e-22 77.5 0.1 1.5e-21 76.6 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK36432.1 - 3.5e-07 30.2 12.6 6.5e-07 29.4 12.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Haem_oxygenas_2 PF14518.6 CRK36432.1 - 0.0033 17.2 0.2 0.0069 16.2 0.2 1.5 1 0 0 1 1 1 1 Iron-containing redox enzyme BatA PF07584.11 CRK36432.1 - 0.28 11.6 4.0 16 5.9 0.3 3.8 4 0 0 4 4 4 0 Aerotolerance regulator N-terminal ThiF PF00899.21 CRK36433.1 - 2.6e-20 72.8 0.0 4.3e-20 72.1 0.0 1.3 1 1 0 1 1 1 1 ThiF family E1_4HB PF16191.5 CRK36433.1 - 0.067 13.4 0.1 1.1 9.5 0.0 2.6 2 0 0 2 2 2 0 Ubiquitin-activating enzyme E1 four-helix bundle adh_short PF00106.25 CRK36434.1 - 1.6e-49 168.0 0.1 3.5e-49 166.9 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK36434.1 - 7.1e-32 110.8 0.4 1.6e-31 109.7 0.4 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK36434.1 - 1.3e-10 41.5 0.0 2.3e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 CRK36434.1 - 0.096 12.5 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase adh_short PF00106.25 CRK36436.1 - 2.2e-27 95.8 0.7 4.4e-27 94.8 0.3 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK36436.1 - 2.2e-23 83.0 0.5 3.4e-23 82.4 0.5 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 CRK36436.1 - 2.1e-18 66.1 0.1 3.7e-18 65.3 0.1 1.3 1 0 0 1 1 1 1 MaoC like domain KR PF08659.10 CRK36436.1 - 3.5e-11 43.3 0.1 5.8e-11 42.6 0.1 1.3 1 0 0 1 1 1 1 KR domain IBR PF01485.21 CRK36438.1 - 5.6e-06 26.5 4.1 5.6e-06 26.5 4.1 4.1 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain adh_short PF00106.25 CRK36439.1 - 1.2e-83 279.4 9.5 1.3e-43 148.8 0.9 2.5 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CRK36439.1 - 3.1e-66 223.3 8.0 1.5e-34 119.6 1.0 2.7 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 CRK36439.1 - 4.8e-34 116.6 0.0 1.1e-33 115.4 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain KR PF08659.10 CRK36439.1 - 7e-30 104.3 4.7 6e-15 55.6 1.0 2.3 2 0 0 2 2 2 2 KR domain MaoC_dehydrat_N PF13452.6 CRK36439.1 - 0.051 13.7 0.0 3.8 7.7 0.0 2.5 2 0 0 2 2 2 0 N-terminal half of MaoC dehydratase THF_DHG_CYH_C PF02882.19 CRK36439.1 - 0.063 12.6 2.0 0.098 12.0 0.6 2.0 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Glucodextran_B PF09136.10 CRK36439.1 - 0.15 12.4 2.4 0.18 12.2 0.2 2.3 2 0 0 2 2 2 0 Glucodextranase, domain B AAA_16 PF13191.6 CRK36440.1 - 1.2e-05 25.7 0.4 0.00015 22.2 0.1 2.1 1 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 CRK36440.1 - 8.6e-05 22.5 0.0 0.00017 21.5 0.0 1.6 2 0 0 2 2 1 1 NACHT domain SRP54 PF00448.22 CRK36440.1 - 0.001 18.7 0.0 0.0015 18.2 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_33 PF13671.6 CRK36440.1 - 0.0014 18.8 0.0 0.0026 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 CRK36440.1 - 0.0014 17.9 0.0 0.0014 17.9 0.0 1.1 1 0 0 1 1 1 1 KAP family P-loop domain AAA_18 PF13238.6 CRK36440.1 - 0.0018 18.8 0.0 0.0035 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 CRK36440.1 - 0.002 17.4 0.0 0.0033 16.7 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin MeaB PF03308.16 CRK36440.1 - 0.0026 16.8 0.0 0.0047 15.9 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB TsaE PF02367.17 CRK36440.1 - 0.0054 16.7 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 CRK36440.1 - 0.02 14.9 0.0 0.039 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 CRK36440.1 - 0.031 14.7 0.0 0.053 13.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ArsA_ATPase PF02374.15 CRK36440.1 - 0.046 12.9 0.0 0.071 12.3 0.0 1.2 1 0 0 1 1 1 0 Anion-transporting ATPase NB-ARC PF00931.22 CRK36440.1 - 0.068 12.4 0.0 0.095 11.9 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Thymidylate_kin PF02223.17 CRK36440.1 - 0.074 12.7 0.0 0.34 10.6 0.0 1.9 2 0 0 2 2 2 0 Thymidylate kinase AAA_5 PF07728.14 CRK36440.1 - 0.078 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MobB PF03205.14 CRK36440.1 - 0.081 12.8 0.0 1.4 8.8 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.23 CRK36440.1 - 0.083 13.0 0.0 0.25 11.4 0.0 1.7 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain NTPase_1 PF03266.15 CRK36440.1 - 0.12 12.2 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 NTPase AAA_22 PF13401.6 CRK36440.1 - 0.12 12.6 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CRK36440.1 - 0.15 11.7 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain Xpo1 PF08389.12 CRK36441.1 - 7.1e-22 78.1 0.3 1.1e-20 74.2 0.0 3.1 3 2 1 5 5 5 1 Exportin 1-like protein Importin_rep_3 PF18806.1 CRK36441.1 - 1.1e-05 25.4 0.1 0.25 11.4 0.0 4.4 4 1 0 4 4 4 1 Importin 13 repeat IBN_N PF03810.19 CRK36441.1 - 1.9e-05 24.5 0.1 7.7e-05 22.5 0.0 2.1 2 0 0 2 2 2 1 Importin-beta N-terminal domain Adaptin_N PF01602.20 CRK36441.1 - 0.011 14.3 0.2 0.51 8.8 0.0 2.6 2 0 0 2 2 2 0 Adaptin N terminal region CHASE6_C PF17150.4 CRK36441.1 - 0.07 13.8 0.3 2.9 8.6 0.1 2.9 2 0 0 2 2 2 0 C-terminal domain of two-partite extracellular sensor domain RVT_N PF13655.6 CRK36441.1 - 0.095 13.0 0.1 0.46 10.8 0.0 2.1 2 0 0 2 2 2 0 N-terminal domain of reverse transcriptase Acetyltransf_1 PF00583.25 CRK36441.1 - 0.097 12.9 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Importin_rep_3 PF18806.1 CRK36442.1 - 0.0063 16.5 0.1 0.098 12.7 0.0 2.7 2 1 1 3 3 3 1 Importin 13 repeat Pox_F16 PF04708.12 CRK36442.1 - 0.095 12.1 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Poxvirus F16 protein AMP-binding PF00501.28 CRK36443.1 - 8e-102 341.0 0.0 1.6e-88 297.1 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme LSM PF01423.22 CRK36443.1 - 3.8e-08 32.9 0.0 1.3e-07 31.2 0.1 1.9 2 0 0 2 2 2 1 LSM domain ESX-1_EspG PF14011.6 CRK36443.1 - 0.0057 16.3 0.0 3.3 7.3 0.0 2.5 2 0 0 2 2 2 2 EspG family AMP-binding_C PF13193.6 CRK36443.1 - 0.045 14.7 0.1 0.13 13.2 0.1 1.8 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Adeno_E1A PF02703.14 CRK36443.1 - 0.061 12.9 0.1 11 5.5 0.0 2.2 2 0 0 2 2 2 0 Early E1A protein CdhD PF03599.16 CRK36443.1 - 0.14 10.8 0.0 0.74 8.5 0.0 1.9 2 0 0 2 2 2 0 CO dehydrogenase/acetyl-CoA synthase delta subunit Acetyltransf_1 PF00583.25 CRK36443.1 - 0.14 12.4 0.0 0.34 11.2 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Hfq PF17209.3 CRK36443.1 - 0.17 11.5 0.1 0.35 10.5 0.1 1.4 1 0 0 1 1 1 0 Hfq protein 5-FTHF_cyc-lig PF01812.20 CRK36444.1 - 7.3e-27 94.4 0.0 9.6e-27 94.0 0.0 1.2 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family adh_short PF00106.25 CRK36445.1 - 4.6e-40 137.2 2.2 8.8e-40 136.2 2.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK36445.1 - 2.9e-31 108.8 1.1 4.5e-31 108.2 1.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK36445.1 - 1.2e-15 57.9 1.0 1.8e-15 57.3 1.0 1.2 1 0 0 1 1 1 1 KR domain EF-hand_1 PF00036.32 CRK36445.1 - 8.8e-06 24.9 0.6 1.9e-05 23.8 0.6 1.5 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 CRK36445.1 - 1.1e-05 25.8 0.1 4.5e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 CRK36445.1 - 6.8e-05 22.5 0.1 0.00016 21.3 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 CRK36445.1 - 0.00023 20.5 0.4 0.00048 19.5 0.4 1.5 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 CRK36445.1 - 0.027 14.3 0.1 0.065 13.1 0.1 1.6 1 0 0 1 1 1 0 EF-hand domain pair THF_DHG_CYH_C PF02882.19 CRK36445.1 - 0.041 13.2 0.3 0.069 12.5 0.3 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AMP-binding PF00501.28 CRK36446.1 - 3.4e-49 167.6 0.0 6.6e-49 166.6 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme NACHT PF05729.12 CRK36446.1 - 0.00056 19.9 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.6 CRK36446.1 - 0.0014 19.2 0.0 0.0065 17.0 0.0 2.1 3 0 0 3 3 3 1 AAA domain AMP-binding_C PF13193.6 CRK36446.1 - 0.0019 19.1 0.1 0.0055 17.6 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain SRP54 PF00448.22 CRK36446.1 - 0.0024 17.5 0.0 0.0045 16.7 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain MeaB PF03308.16 CRK36446.1 - 0.0043 16.1 0.0 0.011 14.8 0.0 1.6 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 CRK36446.1 - 0.0048 17.1 0.0 0.0091 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CRK36446.1 - 0.0049 17.3 0.0 0.011 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain KAP_NTPase PF07693.14 CRK36446.1 - 0.0097 15.2 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 KAP family P-loop domain Zeta_toxin PF06414.12 CRK36446.1 - 0.018 14.3 0.0 0.033 13.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin TsaE PF02367.17 CRK36446.1 - 0.022 14.8 0.0 0.041 13.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 CRK36446.1 - 0.05 14.0 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 CRK36446.1 - 0.063 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain ArsA_ATPase PF02374.15 CRK36446.1 - 0.078 12.2 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Anion-transporting ATPase AAA_30 PF13604.6 CRK36446.1 - 0.11 12.2 0.0 0.62 9.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 CRK36446.1 - 0.11 12.5 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 CRK36446.1 - 0.16 11.1 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_22 PF13401.6 CRK36446.1 - 0.18 12.0 0.0 0.46 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 CRK36446.1 - 0.19 11.7 0.0 0.33 10.9 0.0 1.4 1 0 0 1 1 1 0 NTPase ECM11 PF15463.6 CRK36447.1 - 3.9e-42 144.0 4.0 6.2e-42 143.3 4.0 1.3 1 0 0 1 1 1 1 Extracellular mutant protein 11 5-FTHF_cyc-lig PF01812.20 CRK36448.1 - 3.6e-26 92.2 0.0 4.7e-26 91.8 0.0 1.2 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family EF-hand_1 PF00036.32 CRK36449.1 - 1.2e-48 159.1 29.0 1.3e-07 30.6 0.2 8.8 8 0 0 8 8 8 6 EF hand EF-hand_7 PF13499.6 CRK36449.1 - 1.7e-47 159.7 16.9 2e-15 57.0 1.1 6.8 4 3 3 7 7 7 7 EF-hand domain pair EF-hand_6 PF13405.6 CRK36449.1 - 6.4e-44 144.1 19.5 1.1e-05 25.0 0.1 9.6 8 2 2 10 10 10 8 EF-hand domain EF-hand_5 PF13202.6 CRK36449.1 - 2.2e-32 109.1 29.2 0.00019 20.8 0.1 8.5 8 0 0 8 8 8 6 EF hand EF-hand_8 PF13833.6 CRK36449.1 - 1.2e-27 95.5 27.9 3.3e-05 23.7 0.4 7.1 5 3 1 6 6 6 6 EF-hand domain pair EF-hand_4 PF12763.7 CRK36449.1 - 1.5e-14 53.8 22.5 0.021 14.8 0.1 8.2 4 2 4 8 8 8 4 Cytoskeletal-regulatory complex EF hand Hemerythrin PF01814.23 CRK36449.1 - 1.4e-09 38.7 1.2 3.1e-09 37.5 1.2 1.6 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain EF-hand_9 PF14658.6 CRK36449.1 - 6.6e-08 32.8 5.6 0.044 14.1 0.1 4.7 5 1 0 5 5 5 2 EF-hand domain SPARC_Ca_bdg PF10591.9 CRK36449.1 - 2.8e-06 27.6 13.9 1.6 9.1 0.0 6.0 4 1 1 5 5 5 2 Secreted protein acidic and rich in cysteine Ca binding region Staphylokinase PF02821.16 CRK36449.1 - 3.1e-05 24.4 0.1 23 5.4 0.0 5.1 2 2 2 4 4 4 0 Staphylokinase/Streptokinase family Dockerin_1 PF00404.18 CRK36449.1 - 0.0014 18.8 0.8 27 5.1 0.0 3.4 3 0 0 3 3 3 0 Dockerin type I domain DUF4367 PF14285.6 CRK36449.1 - 0.014 15.8 1.4 63 4.1 0.0 3.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4367) Pan3_PK PF18101.1 CRK36449.1 - 0.015 15.3 1.6 6.4 6.8 0.1 2.9 2 0 0 2 2 2 0 Pan3 Pseudokinase domain EF-hand_2 PF09068.11 CRK36449.1 - 0.039 14.1 2.7 23 5.1 0.0 4.4 6 1 0 6 6 4 0 EF hand Phage_XkdX PF09693.10 CRK36449.1 - 0.099 12.7 0.2 30 4.7 0.0 2.8 2 0 0 2 2 2 0 Phage uncharacterised protein (Phage_XkdX) SHOCT PF09851.9 CRK36449.1 - 0.11 12.3 0.8 20 5.1 0.1 2.7 2 0 0 2 2 2 0 Short C-terminal domain FG-GAP PF01839.23 CRK36449.1 - 0.2 11.8 3.3 78 3.5 0.1 3.4 3 0 0 3 3 3 0 FG-GAP repeat EF-hand_10 PF14788.6 CRK36449.1 - 0.3 11.0 4.9 1.6 8.7 0.1 4.5 5 0 0 5 5 5 0 EF hand Homeodomain PF00046.29 CRK36449.1 - 0.42 10.5 4.2 5.8 6.8 0.4 2.6 2 0 0 2 2 2 0 Homeodomain VCBS PF13517.6 CRK36449.1 - 1.1 9.9 5.8 86 3.8 0.2 3.5 3 0 0 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella EF-hand_14 PF17959.1 CRK36449.1 - 3.3 8.1 10.1 33 4.9 0.0 5.2 9 0 0 9 9 6 0 EF-hand domain CDC45 PF02724.14 CRK36450.1 - 9.6e-215 714.6 5.5 4.2e-170 567.2 7.5 3.3 1 1 1 2 2 2 2 CDC45-like protein Pinin_SDK_N PF04697.13 CRK36450.1 - 0.11 13.2 6.4 0.25 12.0 6.4 1.6 1 0 0 1 1 1 0 pinin/SDK conserved region CSRNP_N PF16019.5 CRK36450.1 - 0.5 10.3 4.4 1.1 9.2 2.1 2.1 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus BUD22 PF09073.10 CRK36450.1 - 0.57 9.5 15.3 0.86 8.9 15.3 1.1 1 0 0 1 1 1 0 BUD22 NPR3 PF03666.13 CRK36450.1 - 6.1 5.5 6.7 9.1 4.9 6.7 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Methyltransf_23 PF13489.6 CRK36451.1 - 1.1e-16 61.1 0.0 1.7e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK36451.1 - 1.1e-07 32.5 0.0 2.1e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK36451.1 - 9.5e-07 29.5 0.0 2.3e-06 28.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CRK36451.1 - 5.8e-06 26.9 0.0 1e-05 26.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK36451.1 - 4.5e-05 23.3 0.0 0.00053 19.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 CRK36451.1 - 0.00081 18.9 0.0 0.0014 18.1 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.13 CRK36451.1 - 0.0096 15.3 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 CRK36451.1 - 0.028 14.0 0.0 0.051 13.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_2 PF00891.18 CRK36451.1 - 0.17 11.2 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_23 PF13489.6 CRK36452.1 - 8.7e-17 61.4 0.0 1.3e-16 60.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK36452.1 - 2.8e-06 27.9 0.0 1.7e-05 25.4 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK36452.1 - 7.2e-05 22.6 0.0 0.00024 20.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK36452.1 - 0.00048 20.8 0.0 0.0011 19.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CRK36452.1 - 0.002 18.7 0.0 0.0056 17.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CRK36452.1 - 0.0021 17.4 0.0 0.0028 17.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase p450 PF00067.22 CRK36453.1 - 7.4e-37 127.2 0.0 1.3e-30 106.6 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 Glyco_hydro_15 PF00723.21 CRK36454.1 - 3.6e-85 286.4 0.0 6.6e-73 246.0 0.0 2.0 2 0 0 2 2 2 2 Glycosyl hydrolases family 15 CBM_20 PF00686.19 CRK36454.1 - 3.5e-18 65.3 0.0 6.7e-18 64.4 0.0 1.5 1 0 0 1 1 1 1 Starch binding domain AvrPto PF11592.8 CRK36454.1 - 0.00079 19.4 0.0 0.62 10.1 0.0 2.5 2 0 0 2 2 2 2 Central core of the bacterial effector protein AvrPto DPPIV_rep PF18811.1 CRK36454.1 - 0.0013 18.6 0.0 2.8 8.0 0.0 2.6 2 0 0 2 2 2 2 Dipeptidyl peptidase IV (DPP IV) low complexity region Fungal_trans PF04082.18 CRK36455.1 - 3.2e-15 55.9 0.0 4.9e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK36455.1 - 3.5e-08 33.4 12.1 6.1e-08 32.7 12.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 CRK36456.1 - 3.7e-41 141.2 67.6 7e-41 140.3 61.2 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Aldo_ket_red PF00248.21 CRK36457.1 - 1.1e-38 133.1 0.0 2.1e-38 132.2 0.0 1.5 1 0 0 1 1 1 1 Aldo/keto reductase family Zn_clus PF00172.18 CRK36457.1 - 3e-08 33.6 12.1 4.9e-08 33.0 12.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Seadorna_Vp10 PF07322.11 CRK36457.1 - 0.23 10.8 0.0 11 5.3 0.0 2.2 2 0 0 2 2 2 0 Seadornavirus Vp10 MFS_1 PF07690.16 CRK36458.1 - 1.6e-41 142.4 69.1 1.7e-41 142.3 62.0 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TFIID-18kDa PF02269.16 CRK36459.1 - 6.4e-27 93.4 0.7 2.8e-26 91.4 0.2 2.3 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit Aldo_ket_red PF00248.21 CRK36459.1 - 3.7e-26 92.0 0.0 6.4e-26 91.2 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family WD40 PF00400.32 CRK36460.1 - 0.014 16.3 0.0 0.031 15.1 0.0 1.6 1 0 0 1 1 1 0 WD domain, G-beta repeat TFIID-18kDa PF02269.16 CRK36461.1 - 1.6e-11 44.1 0.4 6e-11 42.2 0.1 2.1 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit WD40 PF00400.32 CRK36461.1 - 2e-08 34.8 18.5 0.014 16.2 0.0 7.0 6 1 1 7 7 7 3 WD domain, G-beta repeat Pro_3_hydrox_C PF05373.11 CRK36461.1 - 0.082 13.0 0.1 32 4.7 0.0 2.9 3 0 0 3 3 3 0 L-proline 3-hydroxylase, C-terminal WD40 PF00400.32 CRK36462.1 - 9.6e-15 54.7 6.8 0.0043 17.9 0.0 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat Ge1_WD40 PF16529.5 CRK36462.1 - 0.0069 15.4 0.1 5.8 5.8 0.0 3.7 4 0 0 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Mo-co_dimer PF03404.16 CRK36462.1 - 0.14 12.1 0.6 15 5.6 0.2 2.3 2 0 0 2 2 2 0 Mo-co oxidoreductase dimerisation domain DUF2967 PF11179.8 CRK36462.1 - 0.2 9.7 8.1 1.3 7.0 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2967) Ribosomal_S28e PF01200.18 CRK36463.1 - 3e-31 107.2 2.3 3.4e-31 107.0 2.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e PAS_3 PF08447.12 CRK36465.1 - 1.4e-13 51.0 0.0 1.6e-09 38.0 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 CRK36465.1 - 3.8e-07 30.3 0.0 0.00074 19.7 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 CRK36465.1 - 0.0023 17.9 0.0 1.8 8.6 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 CRK36465.1 - 0.0026 18.0 0.2 0.39 11.0 0.0 2.8 3 0 0 3 3 3 1 PAS fold PAS_11 PF14598.6 CRK36465.1 - 0.0032 17.6 0.0 0.011 15.9 0.0 1.8 2 0 0 2 2 2 1 PAS domain Chitin_synth_2 PF03142.15 CRK36466.1 - 2.1e-115 386.3 2.6 2.1e-73 247.8 4.5 2.2 1 1 1 2 2 2 2 Chitin synthase DEK_C PF08766.11 CRK36466.1 - 1.1e-15 57.2 0.5 8.3e-15 54.5 0.8 2.1 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.28 CRK36466.1 - 2.3e-15 56.5 0.2 1.6e-10 41.0 0.0 3.1 3 0 0 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain Myosin_head PF00063.21 CRK36466.1 - 5.9e-08 31.4 0.0 1.7e-07 29.9 0.0 1.6 1 1 0 1 1 1 1 Myosin head (motor domain) FA_desaturase PF00487.24 CRK36466.1 - 1.7 8.4 10.7 2.7 7.8 1.6 2.5 2 0 0 2 2 2 0 Fatty acid desaturase Chitin_synth_2 PF03142.15 CRK36467.1 - 3.5e-248 824.5 3.8 4.8e-248 824.1 3.8 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 CRK36467.1 - 1.4e-60 205.3 0.2 2.5e-56 191.3 0.2 3.1 1 1 0 2 2 2 2 Myosin head (motor domain) Cyt-b5 PF00173.28 CRK36467.1 - 5.9e-18 64.8 0.0 2.5e-13 50.0 0.0 3.7 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.11 CRK36467.1 - 4.9e-17 61.6 0.1 1.4e-16 60.1 0.1 1.9 1 0 0 1 1 1 1 DEK C terminal domain Glyco_trans_2_3 PF13632.6 CRK36467.1 - 5.5e-11 42.8 5.3 5.5e-11 42.8 5.3 2.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 CRK36467.1 - 1.1e-09 38.6 0.2 2.3e-08 34.2 0.2 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 CRK36467.1 - 1.9e-06 27.8 0.0 0.0018 18.1 0.0 2.6 2 0 0 2 2 2 2 Glycosyl transferase family 2 RsgA_GTPase PF03193.16 CRK36467.1 - 0.0064 16.4 0.1 0.017 15.0 0.1 1.7 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 CRK36467.1 - 0.0068 16.0 0.1 0.017 14.7 0.1 1.6 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 CRK36467.1 - 0.0094 16.0 0.1 0.53 10.4 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.27 CRK36467.1 - 0.012 16.2 0.1 0.037 14.5 0.0 1.9 2 0 0 2 2 1 0 ABC transporter AAA_16 PF13191.6 CRK36467.1 - 0.015 15.7 0.3 0.071 13.5 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 CRK36467.1 - 0.053 13.3 0.1 0.19 11.5 0.1 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 CRK36467.1 - 0.056 13.7 0.6 0.25 11.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CRK36467.1 - 0.082 12.4 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 CRK36467.1 - 0.12 12.8 0.0 0.42 11.0 0.0 2.0 1 0 0 1 1 1 0 RNA helicase Glyco_transf_21 PF13506.6 CRK36467.1 - 0.15 11.5 0.3 0.65 9.5 0.3 2.0 1 1 0 1 1 1 0 Glycosyl transferase family 21 ThiF PF00899.21 CRK36468.1 - 7.8e-110 366.0 0.0 3.8e-74 249.1 0.0 2.2 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 CRK36468.1 - 3.1e-91 305.8 0.6 6.4e-91 304.7 0.1 1.8 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 CRK36468.1 - 1.1e-30 106.2 0.1 2.6e-30 105.0 0.1 1.7 2 0 0 2 2 2 1 Ubiquitin fold domain E1_FCCH PF16190.5 CRK36468.1 - 1.7e-30 105.0 0.1 4e-30 103.8 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 CRK36468.1 - 9.2e-24 83.4 1.3 9.2e-24 83.4 1.3 2.1 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 four-helix bundle Mrr_N PF14338.6 CRK36468.1 - 0.064 13.4 0.0 1.2 9.3 0.0 2.5 2 0 0 2 2 2 0 Mrr N-terminal domain DUF3682 PF12446.8 CRK36470.1 - 0.67 10.4 5.5 0.8 10.2 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Adenylsucc_synt PF00709.21 CRK36471.1 - 8.6e-13 48.0 0.0 1.1e-10 41.1 0.0 2.0 1 1 1 2 2 2 2 Adenylosuccinate synthetase PEMT PF04191.13 CRK36472.1 - 2.5e-52 175.7 10.4 2.8e-35 120.9 2.5 2.6 2 0 0 2 2 2 2 Phospholipid methyltransferase HECW_N PF16562.5 CRK36472.1 - 0.085 12.7 0.4 0.32 10.8 0.0 2.0 2 0 0 2 2 2 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 Trypan_PARP PF05887.11 CRK36472.1 - 0.16 11.9 3.4 0.35 10.8 3.4 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Spore_coat_CotO PF14153.6 CRK36472.1 - 0.23 11.3 2.7 0.43 10.5 2.7 1.3 1 0 0 1 1 1 0 Spore coat protein CotO CCDC53 PF10152.9 CRK36472.1 - 7.2 7.0 5.9 13 6.2 5.9 1.4 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF3484 PF11983.8 CRK36472.1 - 8.9 7.5 6.7 23 6.2 6.7 1.6 1 0 0 1 1 1 0 Membrane-attachment and polymerisation-promoting switch EthD PF07110.11 CRK36473.1 - 2.2e-23 83.2 0.3 3.8e-23 82.5 0.3 1.4 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 CRK36473.1 - 0.032 14.7 0.0 0.064 13.7 0.0 1.5 1 1 0 1 1 1 0 Methylmuconolactone methyl-isomerase DeoRC PF00455.22 CRK36475.1 - 0.083 12.8 0.0 0.089 12.7 0.0 1.0 1 0 0 1 1 1 0 DeoR C terminal sensor domain Thioredoxin PF00085.20 CRK36476.1 - 1.5e-26 92.4 0.5 2e-24 85.5 0.0 2.1 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.6 CRK36476.1 - 5.2e-17 62.3 0.2 2.4e-16 60.2 0.2 1.9 2 0 0 2 2 2 1 Thioredoxin-like domain Redoxin PF08534.10 CRK36476.1 - 0.00032 20.5 0.1 0.00068 19.4 0.0 1.6 2 0 0 2 2 2 1 Redoxin Thioredoxin_7 PF13899.6 CRK36476.1 - 0.00077 19.6 0.0 0.002 18.3 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 CRK36476.1 - 0.005 16.2 0.8 0.15 11.4 0.0 2.1 1 1 1 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 CRK36476.1 - 0.01 16.1 0.0 0.027 14.8 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like AhpC-TSA PF00578.21 CRK36476.1 - 0.013 15.5 0.1 0.034 14.1 0.0 1.8 2 0 0 2 2 2 0 AhpC/TSA family Thioredoxin_2 PF13098.6 CRK36476.1 - 0.049 14.1 0.1 0.25 11.8 0.1 2.2 1 1 0 1 1 1 0 Thioredoxin-like domain ADH_N PF08240.12 CRK36477.1 - 1e-26 92.9 0.2 1.2e-26 92.7 0.2 1.0 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DUF3455 PF11937.8 CRK36479.1 - 0.00035 21.0 0.2 0.00057 20.3 0.1 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3455) DUF2990 PF11693.8 CRK36479.1 - 0.00088 19.4 0.3 0.0015 18.6 0.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2990) HATPase_c PF02518.26 CRK36480.1 - 0.0019 18.7 0.0 0.0027 18.2 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAT PF02184.16 CRK36481.1 - 4.3e-10 39.4 16.9 4.8e-06 26.4 0.3 4.4 5 0 0 5 5 5 2 HAT (Half-A-TPR) repeat Suf PF05843.14 CRK36481.1 - 1.1e-07 32.2 1.5 0.00099 19.2 0.0 2.9 2 2 0 2 2 2 2 Suppressor of forked protein (Suf) TPR_14 PF13428.6 CRK36481.1 - 5e-07 30.0 1.8 0.00097 19.8 0.2 3.8 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 CRK36481.1 - 0.00029 21.0 0.1 0.012 15.9 0.0 3.0 3 1 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CRK36481.1 - 0.00035 20.6 1.1 0.44 10.7 0.0 2.5 2 0 0 2 2 2 2 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 CRK36481.1 - 0.00092 19.7 3.5 0.17 12.6 0.2 4.1 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 CRK36481.1 - 0.0021 18.5 0.5 0.33 11.5 0.2 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 CRK36481.1 - 0.01 15.8 0.3 0.033 14.2 0.3 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 CRK36481.1 - 0.014 15.4 0.0 0.4 10.7 0.0 2.7 1 1 1 2 2 2 0 Mad3/BUB1 homology region 1 TPR_2 PF07719.17 CRK36481.1 - 0.02 15.0 8.7 0.18 12.0 0.7 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 CRK36481.1 - 0.085 13.1 0.3 14 6.2 0.4 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 CRK36481.1 - 0.095 13.4 1.8 0.42 11.3 0.4 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 CRK36481.1 - 0.096 12.6 2.3 0.77 9.7 0.6 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Sacchrp_dh_NADP PF03435.18 CRK36483.1 - 4.7e-19 68.9 0.2 5.6e-19 68.7 0.2 1.0 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 CRK36483.1 - 0.057 13.3 0.3 0.09 12.7 0.3 1.4 1 1 0 1 1 1 0 NAD(P)H-binding GFO_IDH_MocA PF01408.22 CRK36483.1 - 0.093 13.6 0.1 0.14 13.0 0.1 1.2 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold SieB PF14163.6 CRK36483.1 - 0.13 11.7 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Super-infection exclusion protein B zf-C3HC4_5 PF17121.5 CRK36484.1 - 5.9e-24 83.7 4.0 8.3e-24 83.2 4.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) MAT1 PF06391.13 CRK36484.1 - 1.6e-23 83.6 0.7 1.9e-23 83.4 0.7 1.0 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4 PF00097.25 CRK36484.1 - 0.0032 17.3 1.6 0.0033 17.3 0.7 1.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CRK36484.1 - 0.0037 17.1 0.7 0.0065 16.3 0.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CRK36484.1 - 0.0049 16.7 1.2 0.0067 16.3 1.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CRK36484.1 - 0.0082 16.1 1.4 0.013 15.5 1.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 CRK36484.1 - 0.02 14.5 0.1 0.03 14.0 0.1 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_6 PF14835.6 CRK36484.1 - 0.031 14.2 1.1 0.27 11.1 1.1 2.1 1 1 0 1 1 1 0 zf-RING of BARD1-type protein Pkinase PF00069.25 CRK36492.1 - 6.1e-56 189.7 0.0 7.4e-56 189.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK36492.1 - 2.7e-27 95.7 0.0 4.1e-27 95.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CRK36492.1 - 0.013 14.8 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Kinase-like FAT PF02259.23 CRK36498.1 - 4.8e-38 131.2 3.3 5.1e-38 131.2 3.3 1.0 1 0 0 1 1 1 1 FAT domain NRDE-2 PF08424.10 CRK36498.1 - 0.067 12.3 1.0 0.14 11.2 0.3 1.6 1 1 1 2 2 2 0 NRDE-2, necessary for RNA interference PRP4 PF08799.11 CRK36499.1 - 4.8e-11 42.0 3.8 7.4e-11 41.4 3.8 1.3 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like MFS_1 PF07690.16 CRK36504.1 - 2.9e-19 69.2 19.6 5.7e-19 68.2 18.3 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily VIT1 PF01988.19 CRK36504.1 - 2.1 8.1 8.2 1.2 8.9 2.9 2.7 1 1 1 2 2 2 0 VIT family GMC_oxred_C PF05199.13 CRK36505.1 - 1.3e-34 119.8 0.1 2.3e-34 119.0 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 CRK36505.1 - 4e-14 52.7 0.1 6.1e-14 52.1 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DUF4691 PF15762.5 CRK36505.1 - 0.07 13.3 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4691) 2Fe-2S_thioredx PF01257.19 CRK36507.1 - 5.3e-21 75.0 0.0 6.2e-21 74.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin ABC_tran PF00005.27 CRK36509.1 - 1.5e-09 38.5 0.0 1.8e-09 38.2 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CRK36509.1 - 0.00085 19.2 0.0 0.00087 19.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 CRK36509.1 - 0.035 14.3 0.1 0.48 10.7 0.1 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit SMC_N PF02463.19 CRK36509.1 - 0.18 11.2 0.0 0.19 11.1 0.0 1.1 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Suc_Fer-like PF06999.12 CRK36510.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Sucrase/ferredoxin-like Hydrolase PF00702.26 CRK36511.1 - 7.2e-05 23.2 0.0 7.6e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Aldedh PF00171.22 CRK36512.1 - 0.16 10.4 0.0 0.16 10.4 0.0 1.0 1 0 0 1 1 1 0 Aldehyde dehydrogenase family IDO PF01231.18 CRK36514.1 - 2.4e-09 36.5 0.0 3.6e-09 35.9 0.0 1.3 1 1 0 1 1 1 1 Indoleamine 2,3-dioxygenase ApbA_C PF08546.11 CRK36514.1 - 0.033 14.4 0.0 0.039 14.1 0.0 1.2 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal RNA_pol_Rpc34 PF05158.12 CRK36515.1 - 2.1e-12 47.1 0.1 2.5e-12 46.9 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit DUF4093 PF13331.6 CRK36515.1 - 0.098 13.1 0.1 0.19 12.2 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4093) ATP-cone PF03477.16 CRK36515.1 - 0.16 12.5 0.0 0.26 11.9 0.0 1.3 1 1 0 1 1 1 0 ATP cone domain IlvN PF07991.12 CRK36517.1 - 2.1e-21 76.2 0.0 2.2e-21 76.1 0.0 1.0 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 CRK36517.1 - 0.0038 17.8 0.0 0.0039 17.7 0.0 1.1 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent CotJA PF11007.8 CRK36517.1 - 0.071 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Spore coat associated protein JA (CotJA) NAD_binding_2 PF03446.15 CRK36517.1 - 0.091 12.9 0.0 0.097 12.8 0.0 1.0 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Cullin PF00888.22 CRK36518.1 - 4.5e-67 227.1 1.5 5e-67 226.9 1.5 1.0 1 0 0 1 1 1 1 Cullin family RRM_1 PF00076.22 CRK36521.1 - 1.5e-06 27.9 0.1 6.6e-06 25.8 0.0 1.9 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SWM_repeat PF13753.6 CRK36521.1 - 0.0047 17.0 0.0 0.0062 16.7 0.0 1.2 1 0 0 1 1 1 1 Putative flagellar system-associated repeat PHM7_cyt PF14703.6 CRK36521.1 - 0.23 11.7 1.3 5.2 7.3 0.1 2.0 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter DUF4633 PF15464.6 CRK36523.1 - 0.9 9.7 11.2 1.2 9.4 11.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4633) DUF2852 PF11014.8 CRK36523.1 - 1.1 9.4 9.0 1.5 9.0 9.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) PXA PF02194.15 CRK36523.1 - 1.4 8.8 5.9 1.6 8.7 5.9 1.2 1 0 0 1 1 1 0 PXA domain PAP_central PF04928.17 CRK36523.1 - 6.2 5.7 7.7 7.4 5.5 7.7 1.1 1 0 0 1 1 1 0 Poly(A) polymerase central domain RIBIOP_C PF04950.12 CRK36523.1 - 9.1 5.6 11.5 10 5.4 11.5 1.1 1 0 0 1 1 1 0 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AAA_12 PF13087.6 CRK36525.1 - 4.7e-20 72.1 0.0 6e-20 71.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain ADH_zinc_N PF00107.26 CRK36526.1 - 5.8e-21 74.8 0.1 6.5e-21 74.7 0.1 1.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CRK36526.1 - 1.4e-05 26.2 0.0 2.2e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Phage_GPA PF05840.13 CRK36526.1 - 0.13 11.3 0.0 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage replication gene A protein (GPA) TMEM43 PF07787.12 CRK36528.1 - 0.097 12.0 0.7 0.11 11.9 0.7 1.1 1 0 0 1 1 1 0 Transmembrane protein 43 Bestrophin PF01062.21 CRK36529.1 - 1.8e-11 44.0 0.8 1.8e-11 44.0 0.8 1.0 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel DUF2207 PF09972.9 CRK36529.1 - 0.11 11.2 1.5 0.13 11.0 1.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) RNA_pol_Rpb2_6 PF00562.28 CRK36531.1 - 1.3e-26 93.6 0.0 1.3e-26 93.6 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 NIR_SIR PF01077.22 CRK36532.1 - 0.00012 21.6 0.0 0.00015 21.3 0.0 1.1 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Ras PF00071.22 CRK36536.1 - 1.4e-27 96.2 0.1 1.5e-27 96.2 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CRK36536.1 - 8.4e-19 68.0 0.2 8.9e-19 67.9 0.2 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CRK36536.1 - 0.0014 18.1 0.1 0.0014 18.1 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CRK36536.1 - 0.045 13.3 0.0 0.045 13.3 0.0 1.1 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain His_Phos_1 PF00300.22 CRK36539.1 - 0.00016 21.4 0.1 0.0002 21.1 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) 6PF2K PF01591.18 CRK36539.1 - 0.012 14.9 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase DUF5457 PF17540.2 CRK36539.1 - 0.15 12.2 0.0 0.2 11.8 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5457) zf-NPL4 PF05020.15 CRK36540.1 - 3.1e-63 212.3 0.4 7e-63 211.1 0.2 1.6 2 0 0 2 2 2 1 NPL4 family, putative zinc binding region RecG_N PF17190.4 CRK36540.1 - 0.038 14.7 1.0 19 6.1 0.0 3.0 1 1 2 3 3 3 0 RecG N-terminal helical domain zf-C2H2 PF00096.26 CRK36542.1 - 2.1e-06 27.9 4.4 3.3e-06 27.3 4.4 1.3 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-met PF12874.7 CRK36542.1 - 4.7e-06 26.8 0.2 7.9e-06 26.1 0.2 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CRK36542.1 - 8.5e-05 22.7 0.7 0.00012 22.3 0.7 1.2 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 CRK36542.1 - 0.0003 21.4 3.8 0.00046 20.8 3.8 1.3 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CRK36542.1 - 1.1 9.4 4.3 4.1 7.5 4.3 1.9 1 1 0 1 1 1 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CRK36542.1 - 1.1 9.8 7.2 1.7 9.2 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger double domain Fungal_trans PF04082.18 CRK36543.1 - 0.12 11.4 1.6 0.17 10.8 1.6 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain Prenyltrans PF00432.21 CRK36545.1 - 0.023 14.4 0.1 0.22 11.3 0.0 1.9 2 0 0 2 2 2 0 Prenyltransferase and squalene oxidase repeat EF-hand_8 PF13833.6 CRK36554.1 - 1.1e-10 41.2 0.0 1.4e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 CRK36554.1 - 9.6e-09 34.2 0.2 4.3e-05 22.8 0.1 2.1 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 CRK36554.1 - 7.9e-07 29.4 0.0 9.3e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_9 PF14658.6 CRK36554.1 - 5.8e-05 23.3 0.0 6.5e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 EF-hand domain EF-hand_6 PF13405.6 CRK36554.1 - 8.3e-05 22.2 1.5 0.21 11.6 0.0 2.5 2 1 1 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 CRK36554.1 - 0.00039 19.8 0.1 0.035 13.6 0.1 2.2 2 0 0 2 2 2 1 EF hand UPF0154 PF03672.13 CRK36554.1 - 0.00059 19.8 0.0 0.0007 19.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0154) FAM176 PF14851.6 CRK36561.1 - 0.0071 16.0 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 FAM176 family ABC_membrane PF00664.23 CRK36561.1 - 0.018 14.7 0.5 0.018 14.7 0.5 2.5 3 1 1 4 4 4 0 ABC transporter transmembrane region APG6 PF04111.12 CRK36562.1 - 7.2e-48 162.9 0.0 1.1e-47 162.2 0.0 1.2 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 CRK36562.1 - 3.1e-22 79.5 8.8 3.1e-22 79.5 8.8 1.8 2 0 0 2 2 2 1 Apg6 coiled-coil region ArAE_2_N PF10337.9 CRK36562.1 - 0.15 11.1 4.2 0.23 10.5 4.2 1.2 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal Pertus-S4-tox PF09275.10 CRK36562.1 - 0.19 12.0 0.0 0.37 11.1 0.0 1.4 1 0 0 1 1 1 0 Pertussis toxin S4 subunit Rpr2 PF04032.16 CRK36562.1 - 0.22 11.8 1.6 0.69 10.2 0.1 2.5 2 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Muted PF14942.6 CRK36562.1 - 0.5 10.7 11.0 0.64 10.4 6.7 2.2 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein Med2 PF11214.8 CRK36562.1 - 5.9 7.1 9.0 2.2 8.5 0.1 2.9 2 1 0 2 2 2 0 Mediator complex subunit 2 Scm3 PF10384.9 CRK36563.1 - 6.3e-21 73.9 0.0 1.5e-20 72.7 0.0 1.7 1 0 0 1 1 1 1 Centromere protein Scm3 Ferlin_C PF16165.5 CRK36563.1 - 0.4 10.6 3.4 0.72 9.8 3.4 1.3 1 0 0 1 1 1 0 Ferlin C-terminus Pkinase PF00069.25 CRK36564.1 - 9.6e-63 212.0 0.1 1.2e-62 211.7 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain DUF3807 PF12720.7 CRK36564.1 - 2.7e-32 112.5 0.1 4.7e-32 111.7 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) Pkinase_Tyr PF07714.17 CRK36564.1 - 3.7e-17 62.5 0.0 5.3e-17 61.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CRK36564.1 - 3.4e-08 33.7 0.0 2.9e-06 27.4 0.1 2.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CRK36564.1 - 0.012 14.4 0.0 0.02 13.7 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Choline_kinase PF01633.20 CRK36564.1 - 0.024 14.2 1.6 0.028 14.0 0.1 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase Kdo PF06293.14 CRK36564.1 - 0.025 13.9 0.0 0.044 13.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CRK36564.1 - 0.056 12.7 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Atg14 PF10186.9 CRK36565.1 - 2.2e-70 237.3 0.0 2.9e-70 236.9 0.0 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 MASE3 PF17159.4 CRK36565.1 - 0.052 13.2 0.0 0.08 12.6 0.0 1.2 1 0 0 1 1 1 0 Membrane-associated sensor domain Spc7_N PF15402.6 CRK36568.1 - 6.4e-187 623.7 106.6 1.4e-99 334.7 65.6 3.6 1 1 1 2 2 2 2 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.11 CRK36568.1 - 0.0005 19.1 0.0 0.0005 19.1 0.0 2.2 3 0 0 3 3 3 1 Spc7 kinetochore protein Ribosomal_S17_N PF16205.5 CRK36569.1 - 6e-32 109.8 1.0 9.8e-32 109.2 1.0 1.4 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 CRK36569.1 - 4.8e-26 90.7 0.2 9.1e-26 89.8 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S17 ER_lumen_recept PF00810.18 CRK36571.1 - 5e-38 131.2 6.1 7.3e-38 130.7 6.1 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor TMF_TATA_bd PF12325.8 CRK36571.1 - 0.019 15.2 1.7 0.055 13.7 1.7 1.7 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF4201 PF13870.6 CRK36571.1 - 0.067 12.9 2.0 0.13 12.0 2.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) LicD PF04991.13 CRK36572.1 - 2.3e-23 83.5 5.5 3.2e-17 63.4 2.3 2.2 1 1 1 2 2 2 2 LicD family ADK PF00406.22 CRK36573.1 - 2.3e-36 125.2 0.0 6.2e-19 68.6 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase ADK_lid PF05191.14 CRK36573.1 - 3.3e-16 59.0 0.0 5.7e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.6 CRK36573.1 - 7.3e-15 55.6 0.0 1e-09 38.9 0.0 2.2 1 1 1 2 2 2 2 AAA domain AAA_18 PF13238.6 CRK36573.1 - 0.00042 20.9 0.0 0.004 17.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CRK36573.1 - 0.0021 18.2 0.0 0.033 14.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 CRK36573.1 - 0.025 14.6 0.1 0.044 13.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CRK36573.1 - 0.17 12.2 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain LETM1 PF07766.13 CRK36574.1 - 3.2e-104 348.0 1.2 7e-104 346.9 1.2 1.6 1 0 0 1 1 1 1 LETM1-like protein PX PF00787.24 CRK36574.1 - 1.1e-34 118.8 4.4 2.9e-18 65.9 0.4 3.1 2 0 0 2 2 2 2 PX domain Peptidase_S8 PF00082.22 CRK36574.1 - 8.4e-23 81.1 1.1 1.6e-22 80.1 1.1 1.4 1 0 0 1 1 1 1 Subtilase family Vps5 PF09325.10 CRK36574.1 - 6.7e-05 22.6 12.4 0.0056 16.3 0.9 3.4 3 0 0 3 3 3 2 Vps5 C terminal like PUMA PF15826.5 CRK36574.1 - 0.0014 18.8 1.5 2.6 8.2 0.2 3.0 2 0 0 2 2 2 2 Bcl-2-binding component 3, p53 upregulated modulator of apoptosis YvrJ PF12841.7 CRK36574.1 - 0.011 15.3 0.7 5.5 6.6 0.1 2.5 2 0 0 2 2 2 0 YvrJ protein family S8_pro-domain PF16470.5 CRK36574.1 - 0.06 14.1 0.1 0.29 11.9 0.1 2.2 1 0 0 1 1 1 0 Peptidase S8 pro-domain FAM153 PF15722.5 CRK36574.1 - 4.1 7.8 9.7 10 6.5 1.3 3.5 3 0 0 3 3 3 0 FAM153 family CCT_2 PF09425.10 CRK36574.1 - 6.9 6.7 8.2 23 5.0 1.1 2.7 2 0 0 2 2 2 0 Divergent CCT motif Peptidase_S8 PF00082.22 CRK36576.1 - 6.4e-34 117.6 2.6 6.4e-34 117.6 2.6 2.1 3 0 0 3 3 3 1 Subtilase family P_proprotein PF01483.20 CRK36576.1 - 2.6e-26 91.5 0.8 6e-26 90.3 0.8 1.7 1 0 0 1 1 1 1 Proprotein convertase P-domain PhoD PF09423.10 CRK36577.1 - 7e-07 28.6 0.0 3.5e-06 26.3 0.0 1.9 1 1 0 1 1 1 1 PhoD-like phosphatase RRM_1 PF00076.22 CRK36578.1 - 9.9e-15 54.1 0.0 1.5e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CRK36578.1 - 0.0046 16.5 0.0 0.0072 15.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rubella_Capsid PF05750.11 CRK36578.1 - 0.012 15.2 4.0 0.012 15.2 4.0 1.9 2 0 0 2 2 2 0 Rubella capsid protein RRM_3 PF08777.11 CRK36578.1 - 0.045 13.8 0.0 0.099 12.7 0.0 1.6 1 0 0 1 1 1 0 RNA binding motif Cep57_CLD_2 PF14197.6 CRK36579.1 - 1.4e-36 124.3 60.6 3.6e-19 68.6 11.0 6.3 5 1 1 6 6 6 4 Centrosome localisation domain of PPC89 Cep57_MT_bd PF06657.13 CRK36579.1 - 2.7e-30 104.6 0.3 2.7e-30 104.6 0.3 5.1 6 1 1 7 7 7 1 Centrosome microtubule-binding domain of Cep57 ATG16 PF08614.11 CRK36579.1 - 0.00022 21.5 34.9 0.00022 21.5 34.9 6.9 4 3 4 8 8 8 1 Autophagy protein 16 (ATG16) HALZ PF02183.18 CRK36579.1 - 0.00028 21.1 41.1 0.0088 16.3 2.6 8.7 6 2 2 8 8 8 3 Homeobox associated leucine zipper Cnn_1N PF07989.11 CRK36579.1 - 0.024 14.8 0.6 0.024 14.8 0.6 7.6 3 2 3 6 6 6 0 Centrosomin N-terminal motif 1 ZapB PF06005.12 CRK36579.1 - 0.025 15.0 63.4 0.18 12.2 6.6 8.3 2 1 5 7 7 7 0 Cell division protein ZapB Pox_A_type_inc PF04508.12 CRK36579.1 - 0.11 12.4 2.3 0.65 9.9 0.1 3.6 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Mod_r PF07200.13 CRK36579.1 - 5 7.2 60.4 0.072 13.2 10.5 6.7 3 1 4 7 7 7 0 Modifier of rudimentary (Mod(r)) protein KASH_CCD PF14662.6 CRK36579.1 - 5.9 6.7 72.6 0.069 13.0 14.5 5.6 3 1 2 5 5 5 0 Coiled-coil region of CCDC155 or KASH NPV_P10 PF05531.12 CRK36579.1 - 6.3 7.3 25.5 8.7 6.9 5.8 6.0 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Glyco_hydro_76 PF03663.14 CRK36580.1 - 7.3e-22 78.4 0.3 1.6e-19 70.6 0.3 3.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 Peptidase_M28 PF04389.17 CRK36581.1 - 5.9e-34 117.5 0.0 9.7e-34 116.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 adh_short PF00106.25 CRK36582.1 - 2.8e-36 124.8 0.6 3.8e-36 124.4 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK36582.1 - 3e-28 99.0 2.1 3.8e-28 98.6 2.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK36582.1 - 2.5e-12 47.1 1.2 3.6e-12 46.6 1.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CRK36582.1 - 0.00098 18.7 0.4 0.0013 18.2 0.4 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 CRK36582.1 - 0.0056 16.3 0.3 0.012 15.2 0.2 1.5 1 1 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 CRK36582.1 - 0.01 15.0 0.7 0.017 14.2 0.7 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain TrkA_N PF02254.18 CRK36582.1 - 0.027 14.7 0.2 0.076 13.3 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain ADH_zinc_N PF00107.26 CRK36582.1 - 0.12 12.3 4.3 0.29 11.1 3.4 2.0 1 1 0 1 1 1 0 Zinc-binding dehydrogenase F-box-like PF12937.7 CRK36583.1 - 0.00026 20.8 0.0 0.0012 18.7 0.0 2.3 1 0 0 1 1 1 1 F-box-like PX PF00787.24 CRK36584.1 - 2.5e-15 56.4 0.0 3.8e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 PX domain IQ PF00612.27 CRK36585.1 - 0.00062 19.3 2.5 0.0019 17.8 2.5 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif Glyco_hydro_100 PF12899.7 CRK36585.1 - 0.14 10.8 0.2 0.96 8.0 0.2 1.9 2 0 0 2 2 2 0 Alkaline and neutral invertase Anophelin PF10731.9 CRK36585.1 - 0.17 11.8 0.3 0.46 10.4 0.3 1.7 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito PhoD PF09423.10 CRK36586.1 - 8.4e-07 28.3 0.0 4.9e-06 25.8 0.0 2.0 1 1 0 1 1 1 1 PhoD-like phosphatase RRM_1 PF00076.22 CRK36587.1 - 9.5e-15 54.2 0.0 1.5e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CRK36587.1 - 0.0044 16.6 0.0 0.0069 16.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 CRK36587.1 - 0.048 13.7 0.0 0.095 12.8 0.0 1.5 1 0 0 1 1 1 0 RNA binding motif Rubella_Capsid PF05750.11 CRK36587.1 - 0.69 9.5 10.8 0.026 14.1 3.6 1.8 2 0 0 2 2 2 0 Rubella capsid protein Cep57_CLD_2 PF14197.6 CRK36588.1 - 9.4e-37 124.9 62.2 4.8e-19 68.2 11.4 6.3 5 1 1 6 6 6 4 Centrosome localisation domain of PPC89 Cep57_MT_bd PF06657.13 CRK36588.1 - 2.7e-30 104.6 0.3 2.7e-30 104.6 0.3 5.1 5 1 1 7 7 6 1 Centrosome microtubule-binding domain of Cep57 HALZ PF02183.18 CRK36588.1 - 7e-05 23.0 41.4 0.0061 16.7 1.8 8.7 6 2 2 8 8 8 3 Homeobox associated leucine zipper ATG16 PF08614.11 CRK36588.1 - 0.00013 22.3 36.3 0.00013 22.3 36.3 7.0 4 3 4 8 8 7 1 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 CRK36588.1 - 0.0041 17.1 14.8 0.0041 17.1 14.8 6.9 5 1 3 8 8 8 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ZapB PF06005.12 CRK36588.1 - 0.018 15.5 66.3 0.092 13.2 7.7 8.3 2 1 6 8 8 7 0 Cell division protein ZapB Cnn_1N PF07989.11 CRK36588.1 - 0.026 14.7 0.7 0.026 14.7 0.7 7.6 3 2 4 7 7 7 0 Centrosomin N-terminal motif 1 Pox_A_type_inc PF04508.12 CRK36588.1 - 0.11 12.4 2.3 0.65 9.9 0.1 3.6 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat KASH_CCD PF14662.6 CRK36588.1 - 3.7 7.3 73.7 0.045 13.6 15.3 5.5 3 1 2 5 5 5 0 Coiled-coil region of CCDC155 or KASH Mod_r PF07200.13 CRK36588.1 - 6.8 6.8 62.0 0.21 11.7 11.3 6.9 3 1 3 6 6 6 0 Modifier of rudimentary (Mod(r)) protein bZIP_1 PF00170.21 CRK36588.1 - 8.4 6.6 55.8 0.1 12.7 1.7 9.2 7 3 2 10 10 10 0 bZIP transcription factor NPV_P10 PF05531.12 CRK36588.1 - 9.3 6.8 26.1 8.7 6.9 5.8 6.1 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Glyco_hydro_76 PF03663.14 CRK36589.1 - 1.9e-22 80.3 0.2 3.5e-20 72.9 0.2 3.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 adh_short PF00106.25 CRK36590.1 - 9.9e-37 126.3 0.4 1.3e-36 125.9 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK36590.1 - 1.4e-27 96.7 3.0 1.8e-27 96.4 3.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK36590.1 - 1.4e-12 47.9 0.8 2e-12 47.4 0.8 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CRK36590.1 - 0.00061 19.3 0.5 0.00083 18.9 0.5 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 CRK36590.1 - 0.0033 17.0 0.5 0.0088 15.6 0.2 1.8 1 1 0 2 2 2 1 NmrA-like family RmlD_sub_bind PF04321.17 CRK36590.1 - 0.014 14.5 0.7 0.024 13.7 0.7 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain TrkA_N PF02254.18 CRK36590.1 - 0.029 14.6 0.2 0.086 13.1 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain ADH_zinc_N PF00107.26 CRK36590.1 - 0.058 13.4 4.7 0.23 11.4 3.6 2.3 1 1 0 1 1 1 0 Zinc-binding dehydrogenase CDP-OH_P_transf PF01066.21 CRK36591.1 - 2.6e-16 60.1 0.3 2.6e-16 60.1 0.3 2.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase PX PF00787.24 CRK36592.1 - 2.3e-15 56.6 0.0 3.4e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 PX domain IQ PF00612.27 CRK36593.1 - 0.00057 19.4 2.5 0.0019 17.8 2.5 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif Glyco_hydro_100 PF12899.7 CRK36593.1 - 0.13 10.9 0.2 0.54 8.9 0.2 1.8 2 0 0 2 2 2 0 Alkaline and neutral invertase Anophelin PF10731.9 CRK36593.1 - 0.16 11.8 0.4 0.42 10.5 0.4 1.6 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito SAS4 PF15460.6 CRK36594.1 - 3.8e-31 107.1 0.1 1.6e-30 105.1 0.1 2.1 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 RNA_pol_3_Rpc31 PF11705.8 CRK36594.1 - 0.008 16.5 14.7 0.008 16.5 14.7 3.1 2 1 1 3 3 3 1 DNA-directed RNA polymerase III subunit Rpc31 Shadoo PF14999.6 CRK36594.1 - 0.017 15.2 8.4 0.046 13.8 8.4 1.7 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective YbgS PF13985.6 CRK36594.1 - 0.28 11.5 5.4 0.81 10.0 5.4 1.7 1 0 0 1 1 1 0 YbgS-like protein DNA_pol_phi PF04931.13 CRK36594.1 - 1.7 6.7 31.0 2.9 5.9 31.0 1.3 1 0 0 1 1 1 0 DNA polymerase phi DUF2722 PF10846.8 CRK36594.1 - 3.8 6.4 31.0 3.3 6.6 0.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2722) Adaptin_binding PF10199.9 CRK36594.1 - 7 7.3 31.0 0.036 14.7 11.4 3.3 2 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 Peptidase_M1_N PF17900.1 CRK36595.1 - 3.9e-06 27.2 0.0 0.06 13.5 0.0 2.5 2 0 0 2 2 2 2 Peptidase M1 N-terminal domain Cation_efflux PF01545.21 CRK36596.1 - 9.7e-48 162.5 8.8 4.5e-47 160.4 8.8 1.8 1 1 0 1 1 1 1 Cation efflux family DUF202 PF02656.15 CRK36597.1 - 2.7e-14 53.3 1.0 2.7e-14 53.3 1.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Claudin_2 PF13903.6 CRK36597.1 - 0.32 10.7 5.9 0.17 11.6 4.0 1.5 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Glyco_hydro_3_C PF01915.22 CRK36598.1 - 1e-62 211.7 0.0 2e-62 210.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 CRK36598.1 - 8.1e-56 189.7 0.0 1.5e-55 188.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 CRK36598.1 - 5e-21 74.6 0.0 1.2e-20 73.4 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 CRK36598.1 - 5.3e-21 75.0 0.0 1.2e-20 73.8 0.0 1.7 1 0 0 1 1 1 1 PA14 domain Metallophos PF00149.28 CRK36598.1 - 6.8e-09 36.5 4.1 1.3e-05 25.9 0.8 2.9 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase Membralin PF09746.9 CRK36598.1 - 0.027 13.5 0.2 6.3 5.7 0.0 2.2 2 0 0 2 2 2 0 Tumour-associated protein PMEI PF04043.15 CRK36598.1 - 0.1 13.0 0.1 21 5.4 0.0 2.5 2 0 0 2 2 2 0 Plant invertase/pectin methylesterase inhibitor RESP18 PF14948.6 CRK36598.1 - 0.12 12.7 0.0 27 5.2 0.0 2.6 2 0 0 2 2 2 0 RESP18 domain Epiglycanin_C PF14654.6 CRK36601.1 - 0.08 13.0 0.2 0.17 12.0 0.2 1.5 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region PetM PF08041.11 CRK36601.1 - 4.4 7.0 7.2 7.9 6.2 7.2 1.4 1 0 0 1 1 1 0 PetM family of cytochrome b6f complex subunit 7 SAS4 PF15460.6 CRK36602.1 - 5.6e-24 84.1 1.2 5.6e-24 84.1 1.2 2.3 2 0 0 2 2 1 1 Something about silencing, SAS, complex subunit 4 Adaptin_binding PF10199.9 CRK36602.1 - 0.002 18.8 11.6 0.004 17.7 11.6 1.6 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 BSP_II PF05432.11 CRK36602.1 - 0.0034 17.2 10.5 0.0042 16.8 10.5 1.1 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) RNA_pol_3_Rpc31 PF11705.8 CRK36602.1 - 0.012 15.9 16.7 0.023 14.9 16.7 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 TFIIF_alpha PF05793.12 CRK36602.1 - 0.021 13.4 14.6 0.025 13.2 14.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BUD22 PF09073.10 CRK36602.1 - 0.023 14.1 16.0 0.032 13.6 16.0 1.4 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 CRK36602.1 - 0.029 12.6 16.3 0.03 12.6 16.3 1.1 1 0 0 1 1 1 0 Nop14-like family Pox_Ag35 PF03286.14 CRK36602.1 - 0.081 12.7 11.9 0.14 11.9 11.9 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DNA_pol_phi PF04931.13 CRK36602.1 - 0.1 10.7 27.9 0.14 10.2 27.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi DUF4820 PF16091.5 CRK36602.1 - 0.22 10.9 6.1 0.33 10.3 6.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) CDC45 PF02724.14 CRK36602.1 - 0.24 9.6 16.1 0.3 9.3 16.1 1.2 1 0 0 1 1 1 0 CDC45-like protein TFB6 PF17110.5 CRK36602.1 - 0.26 11.0 4.1 0.39 10.4 4.1 1.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH PNISR PF15996.5 CRK36602.1 - 0.32 11.2 17.3 0.68 10.2 17.3 1.5 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR DUF1682 PF07946.14 CRK36602.1 - 0.32 10.2 10.7 0.79 8.9 10.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) RPN2_C PF18004.1 CRK36602.1 - 0.48 10.3 9.7 1.2 9.0 9.7 1.8 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain TRM13 PF05206.14 CRK36602.1 - 0.63 9.5 3.3 0.96 8.9 3.3 1.2 1 0 0 1 1 1 0 Methyltransferase TRM13 Paf1 PF03985.13 CRK36602.1 - 0.84 8.6 16.8 1.3 7.9 16.8 1.3 1 0 0 1 1 1 0 Paf1 RR_TM4-6 PF06459.12 CRK36602.1 - 1.5 8.5 9.3 2 8.2 9.3 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3306 PF11748.8 CRK36602.1 - 2.4 9.1 16.2 2.6 8.9 14.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3306) Presenilin PF01080.17 CRK36602.1 - 2.7 6.7 5.4 2.7 6.6 5.4 1.2 1 0 0 1 1 1 0 Presenilin Vfa1 PF08432.10 CRK36602.1 - 4.3 7.6 14.5 0.59 10.4 10.3 1.8 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Astro_capsid_p PF12226.8 CRK36602.1 - 4.5 6.3 18.6 7 5.7 18.6 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Peptidase_M1_N PF17900.1 CRK36603.1 - 2.4e-06 27.9 0.0 0.048 13.8 0.0 2.5 2 0 0 2 2 2 2 Peptidase M1 N-terminal domain HEAT PF02985.22 CRK36603.1 - 0.019 15.2 0.0 8.5 6.9 0.0 3.1 2 0 0 2 2 2 0 HEAT repeat HEAT_2 PF13646.6 CRK36603.1 - 0.049 14.0 0.0 0.24 11.8 0.0 2.2 1 0 0 1 1 1 0 HEAT repeats Cation_efflux PF01545.21 CRK36604.1 - 7.4e-48 162.9 8.5 3.4e-47 160.7 8.5 1.8 1 1 0 1 1 1 1 Cation efflux family DUF202 PF02656.15 CRK36605.1 - 2.7e-14 53.3 1.0 2.7e-14 53.3 1.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Claudin_2 PF13903.6 CRK36605.1 - 0.36 10.6 5.7 0.18 11.6 3.8 1.5 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Glyco_hydro_3_C PF01915.22 CRK36606.1 - 5.8e-63 212.5 0.0 1.2e-62 211.5 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 CRK36606.1 - 8.6e-55 186.3 0.0 1.4e-54 185.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain PA14 PF07691.12 CRK36606.1 - 7.2e-23 81.0 0.0 1.3e-22 80.2 0.0 1.5 1 0 0 1 1 1 1 PA14 domain Fn3-like PF14310.6 CRK36606.1 - 9.2e-22 76.9 0.0 2e-21 75.9 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain ABC_membrane_2 PF06472.15 CRK36608.1 - 8.3e-93 310.7 0.6 4e-91 305.2 0.1 2.4 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 CRK36608.1 - 2.6e-05 24.7 0.0 6e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 ABC transporter End3 PF12761.7 CRK36608.1 - 0.022 14.9 0.9 0.056 13.6 0.9 1.6 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 AAA_21 PF13304.6 CRK36608.1 - 0.039 13.8 0.0 0.078 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CRK36608.1 - 0.056 13.9 1.3 0.22 12.0 1.3 1.9 1 1 0 1 1 1 0 AAA domain RuvB_N PF05496.12 CRK36608.1 - 0.069 12.9 0.0 0.21 11.3 0.0 1.8 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CRK36608.1 - 0.07 13.5 0.0 0.2 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Epiglycanin_C PF14654.6 CRK36608.1 - 0.16 12.0 0.2 0.47 10.6 0.2 1.7 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region AAA PF00004.29 CRK36608.1 - 0.2 12.1 0.0 0.46 10.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 CRK36608.1 - 0.21 11.0 0.0 0.38 10.1 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PetM PF08041.11 CRK36608.1 - 8.9 6.0 6.7 19 4.9 6.7 1.5 1 0 0 1 1 1 0 PetM family of cytochrome b6f complex subunit 7 NIF PF03031.18 CRK36609.1 - 1.6e-54 183.9 0.2 2.1e-54 183.6 0.2 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Glyco_transf_28 PF03033.20 CRK36610.1 - 6.2e-21 74.9 0.5 1.7e-12 47.6 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase family 28 N-terminal domain UIM PF02809.20 CRK36610.1 - 3.6e-05 23.4 39.1 0.21 11.6 0.2 7.8 8 0 0 8 8 8 5 Ubiquitin interaction motif PAF-AH_p_II PF03403.13 CRK36613.1 - 1.6e-48 165.2 0.0 1.1e-23 83.4 0.0 3.2 3 1 0 3 3 3 3 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 CRK36613.1 - 7.4e-07 28.3 0.0 6e-06 25.4 0.0 2.1 2 0 0 2 2 2 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 CRK36613.1 - 4.9e-05 22.7 0.0 0.16 11.2 0.0 3.1 4 0 0 4 4 4 2 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 CRK36613.1 - 9.5e-05 21.6 0.0 0.00057 19.0 0.0 2.0 2 0 0 2 2 2 1 Chlorophyllase DLH PF01738.18 CRK36613.1 - 0.12 11.9 0.0 1.1 8.7 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Pkinase_Tyr PF07714.17 CRK36614.1 - 6.6e-05 22.3 0.0 0.25 10.6 0.0 3.0 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 CRK36614.1 - 0.00048 19.6 0.0 0.084 12.2 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain NIF PF03031.18 CRK36615.1 - 2.8e-54 183.1 0.2 3.8e-54 182.7 0.2 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Aldo_ket_red PF00248.21 CRK36617.1 - 2.8e-40 138.4 0.0 3.5e-40 138.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family LRR_4 PF12799.7 CRK36618.1 - 3.6e-46 154.4 35.5 5.3e-08 33.0 0.0 6.4 1 1 9 10 10 10 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CRK36618.1 - 7.4e-24 83.3 15.1 9.6e-08 31.7 2.0 5.1 1 1 4 6 6 6 6 Leucine rich repeat LRR_9 PF14580.6 CRK36618.1 - 1.7e-16 60.2 6.8 2e-06 27.5 0.8 3.4 1 1 2 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 CRK36618.1 - 2.2e-07 30.4 13.7 0.017 15.1 0.2 7.6 8 0 0 8 8 8 2 Leucine Rich repeat LRR_1 PF00560.33 CRK36618.1 - 0.0013 18.9 16.0 32 5.6 0.3 8.1 8 1 1 9 9 9 1 Leucine Rich Repeat Hydrolase_4 PF12146.8 CRK36619.1 - 0.0015 17.8 0.0 0.023 14.0 0.0 2.1 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CRK36619.1 - 0.0016 18.1 0.0 0.07 12.8 0.0 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold PCI PF01399.27 CRK36620.1 - 4.3e-13 49.7 0.0 1.3e-12 48.2 0.0 1.8 2 0 0 2 2 2 1 PCI domain PriCT_2 PF08707.11 CRK36620.1 - 0.23 11.9 1.4 0.93 9.9 0.4 2.5 3 1 1 4 4 4 0 Primase C terminal 2 (PriCT-2) Ribosomal_L18A PF01775.17 CRK36621.1 - 8.2e-54 180.9 0.5 1e-53 180.6 0.5 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Fungal_trans PF04082.18 CRK36622.1 - 1e-16 60.8 0.1 1.8e-16 60.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK36622.1 - 5.8e-08 32.7 13.1 8.7e-08 32.2 13.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acetyltransf_3 PF13302.7 CRK36624.1 - 7e-30 104.5 0.0 9.4e-30 104.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CRK36624.1 - 0.037 14.2 0.0 1.4 9.2 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family FR47 PF08445.10 CRK36624.1 - 0.15 12.0 0.0 2.8 8.0 0.0 2.5 3 0 0 3 3 3 0 FR47-like protein DUF765 PF05570.11 CRK36624.1 - 0.33 11.2 1.8 0.87 9.8 1.8 1.7 1 0 0 1 1 1 0 Circovirus protein of unknown function (DUF765) HZS_alpha PF18582.1 CRK36624.1 - 1.2 9.6 3.7 33 5.0 0.0 3.5 2 2 1 3 3 3 0 Hydrazine synthase alpha subunit middle domain Fungal_trans_2 PF11951.8 CRK36627.1 - 1.1e-08 34.4 4.9 2.2e-07 30.0 0.1 2.9 2 1 1 3 3 3 2 Fungal specific transcription factor domain PHC2_SAM_assoc PF16616.5 CRK36627.1 - 0.15 12.8 7.8 0.3 11.9 7.8 1.4 1 0 0 1 1 1 0 Unstructured region on Polyhomeotic-like protein 1 and 2 DUF1465 PF07323.12 CRK36627.1 - 0.35 10.7 1.9 8.6 6.2 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1465) Macoilin PF09726.9 CRK36627.1 - 0.55 8.7 1.6 0.69 8.4 1.6 1.1 1 0 0 1 1 1 0 Macoilin family SR-25 PF10500.9 CRK36627.1 - 2 7.9 12.4 3.2 7.3 12.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Peptidase_C27 PF05407.12 CRK36627.1 - 2.4 8.2 11.3 0.92 9.6 0.1 3.5 4 0 0 4 4 4 0 Rubella virus endopeptidase CENP-N PF05238.13 CRK36628.1 - 0.66 9.2 4.9 0.79 9.0 4.9 1.0 1 0 0 1 1 1 0 Kinetochore protein CHL4 like DUF1770 PF08589.10 CRK36628.1 - 2.4 9.2 9.1 3.7 8.6 9.1 1.4 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1770) Presenilin PF01080.17 CRK36628.1 - 2.5 6.8 5.8 2.5 6.8 5.8 1.0 1 0 0 1 1 1 0 Presenilin SelP_N PF04592.14 CRK36628.1 - 7 6.0 15.7 9.1 5.6 15.7 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Velvet PF11754.8 CRK36628.1 - 7 6.5 11.9 8.5 6.2 11.9 1.1 1 0 0 1 1 1 0 Velvet factor WD40 PF00400.32 CRK36629.1 - 3.3e-08 34.1 0.6 0.04 14.8 0.0 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK36629.1 - 0.00067 19.9 0.0 0.035 14.4 0.0 2.4 1 1 2 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 CRK36629.1 - 0.008 15.8 0.1 0.03 13.9 0.0 1.8 1 1 0 1 1 1 1 PQQ-like domain PQQ PF01011.21 CRK36629.1 - 0.025 14.5 0.5 0.091 12.7 0.0 2.1 2 0 0 2 2 2 0 PQQ enzyme repeat PQQ_3 PF13570.6 CRK36629.1 - 0.039 14.5 0.3 0.84 10.2 0.0 2.7 3 0 0 3 3 3 0 PQQ-like domain Frtz PF11768.8 CRK36629.1 - 0.043 12.1 0.0 0.16 10.3 0.0 1.7 1 1 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Tae4 PF14113.6 CRK36629.1 - 0.068 13.4 0.2 0.12 12.6 0.2 1.6 1 1 0 1 1 1 0 Type VI secretion system (T6SS), amidase effector protein 4 VWA_2 PF13519.6 CRK36632.1 - 2.4e-20 73.2 0.1 2.6e-20 73.0 0.1 1.0 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 CRK36632.1 - 2.4e-05 24.6 0.1 2.7e-05 24.5 0.1 1.0 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.14 CRK36632.1 - 0.00014 21.7 0.0 0.00015 21.6 0.0 1.0 1 0 0 1 1 1 1 Ssl1-like Sugar_tr PF00083.24 CRK36634.1 - 2.5e-10 39.8 0.7 2.6e-10 39.8 0.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK36634.1 - 2.6e-05 23.3 0.9 2.7e-05 23.3 0.9 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Cullin PF00888.22 CRK36635.1 - 8e-20 71.0 0.0 8.7e-20 70.9 0.0 1.0 1 0 0 1 1 1 1 Cullin family DUF416 PF04222.12 CRK36636.1 - 0.084 12.3 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF416) Cpn60_TCP1 PF00118.24 CRK36641.1 - 3.6e-23 82.0 0.0 4.6e-23 81.6 0.0 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PrpR_N PF06506.11 CRK36641.1 - 0.028 14.0 0.1 0.049 13.2 0.1 1.3 1 0 0 1 1 1 0 Propionate catabolism activator EAL PF00563.20 CRK36641.1 - 0.047 13.2 0.0 0.067 12.7 0.0 1.2 1 0 0 1 1 1 0 EAL domain Ribosomal_L37ae PF01780.19 CRK36642.1 - 9.2e-22 76.9 2.5 9.7e-22 76.9 2.5 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Mito_carr PF00153.27 CRK36643.1 - 2.8e-12 46.4 0.0 3.1e-12 46.2 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial carrier protein Erf4 PF10256.9 CRK36644.1 - 1.9e-28 98.9 0.0 2.2e-28 98.7 0.0 1.0 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Luteo_Vpg PF01659.16 CRK36652.1 - 0.043 14.1 0.0 0.058 13.7 0.0 1.2 1 0 0 1 1 1 0 Luteovirus putative VPg genome linked protein Ilm1 PF10311.9 CRK36656.1 - 6.5e-13 48.7 0.0 6.9e-13 48.6 0.0 1.0 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 WSC PF01822.19 CRK36658.1 - 6.1e-08 32.7 0.2 1.5e-07 31.5 0.2 1.7 1 0 0 1 1 1 1 WSC domain G-gamma PF00631.22 CRK36659.1 - 1e-24 86.3 0.0 1.3e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 GGL domain SARAF PF06682.12 CRK36662.1 - 8e-39 134.2 0.0 8.7e-39 134.1 0.0 1.0 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis PALP PF00291.25 CRK36666.1 - 5.8e-14 52.2 0.4 6.5e-14 52.0 0.4 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme RRP7 PF12923.7 CRK36668.1 - 5.8e-23 81.3 8.8 6.3e-23 81.2 8.8 1.0 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain BOP1NT PF08145.12 CRK36675.1 - 3.4e-56 191.1 9.5 3.7e-56 190.9 9.5 1.0 1 0 0 1 1 1 1 BOP1NT (NUC169) domain Nop53 PF07767.11 CRK36675.1 - 0.004 16.6 6.9 0.25 10.7 6.6 2.7 1 1 1 2 2 2 1 Nop53 (60S ribosomal biogenesis) DcpS PF05652.12 CRK36676.1 - 3.5e-29 101.7 0.0 3.9e-29 101.6 0.0 1.0 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal OMPdecase PF00215.24 CRK36680.1 - 2.2e-28 99.4 0.0 2.7e-28 99.1 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Peptidase_M3 PF01432.20 CRK36681.1 - 1.1e-16 61.1 0.0 1.3e-16 61.0 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M3 Amelogenin PF02948.15 CRK36684.1 - 0.27 11.9 4.6 0.32 11.6 4.6 1.1 1 0 0 1 1 1 0 Amelogenin Sortilin-Vps10 PF15902.5 CRK36686.1 - 5.4e-09 35.4 0.0 5.8e-09 35.2 0.0 1.0 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, Glyco_hydro_16 PF00722.21 CRK36688.1 - 3.2e-20 72.3 0.0 3.4e-20 72.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Utp12 PF04003.12 CRK36690.1 - 1.8e-09 37.9 0.1 2.4e-09 37.5 0.1 1.1 1 0 0 1 1 1 1 Dip2/Utp12 Family NPC1_N PF16414.5 CRK36692.1 - 7.8e-15 55.1 0.9 8.9e-15 54.9 0.9 1.0 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus W2 PF02020.18 CRK36693.1 - 1e-11 44.8 0.0 1.2e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon ScsC_N PF18312.1 CRK36693.1 - 0.18 11.6 0.0 0.39 10.6 0.0 1.6 1 0 0 1 1 1 0 Copper resistance protein ScsC N-terminal domain Sugar_tr PF00083.24 CRK36698.1 - 3.1e-94 316.4 16.8 4e-94 316.0 16.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK36698.1 - 1.6e-18 66.8 32.7 7e-11 41.6 10.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Gal11_ABD1 PF18535.1 CRK36698.1 - 0.74 9.9 3.2 0.32 11.1 0.3 1.9 2 0 0 2 2 2 0 Gal11 activator-binding domain (ABD1) Hce2 PF14856.6 CRK36700.1 - 0.026 14.8 0.6 0.051 13.9 0.6 1.5 1 0 0 1 1 1 0 Pathogen effector; putative necrosis-inducing factor DUF5385 PF17359.2 CRK36700.1 - 0.11 12.0 0.1 0.17 11.5 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5385) Peptidase_C2 PF00648.21 CRK36701.1 - 9.2e-16 57.7 1.3 1.4e-15 57.1 1.3 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease ABG_transport PF03806.13 CRK36701.1 - 0.046 12.0 1.3 0.06 11.6 1.3 1.1 1 0 0 1 1 1 0 AbgT putative transporter family Glyco_hydro_43 PF04616.14 CRK36702.1 - 3.8e-13 49.4 4.0 3.4e-11 43.0 1.0 1.7 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 tRNA-synt_1g PF09334.11 CRK36704.1 - 3e-136 454.2 3.1 1.1e-132 442.5 3.1 3.2 1 1 0 1 1 1 1 tRNA synthetases class I (M) ADH_N PF08240.12 CRK36704.1 - 8e-25 86.8 3.8 1.5e-24 86.0 3.8 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain tRNA-synt_1 PF00133.22 CRK36704.1 - 0.0014 17.0 6.0 0.004 15.5 0.0 3.5 4 1 1 5 5 5 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CRK36704.1 - 0.0086 16.0 0.3 0.018 15.0 0.3 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA WD40 PF00400.32 CRK36707.1 - 7e-28 96.3 15.6 7.9e-06 26.5 0.1 7.9 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.7 CRK36707.1 - 1e-11 44.5 0.2 2.5e-11 43.3 0.2 1.7 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 CRK36707.1 - 1.8e-06 28.2 0.2 0.004 17.4 0.0 4.3 2 1 4 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CRK36707.1 - 0.00018 20.3 0.1 2.1 6.9 0.0 3.2 2 1 1 3 3 3 2 Nucleoporin Nup120/160 F-box PF00646.33 CRK36707.1 - 0.00064 19.5 0.1 0.0012 18.6 0.1 1.5 1 0 0 1 1 1 1 F-box domain Cytochrom_D1 PF02239.16 CRK36707.1 - 0.043 12.3 0.0 0.082 11.4 0.0 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain Frtz PF11768.8 CRK36707.1 - 0.049 11.9 0.1 0.13 10.5 0.0 1.7 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz STE PF02200.16 CRK36707.1 - 0.17 12.4 0.1 3.5 8.1 0.0 2.4 2 0 0 2 2 2 0 STE like transcription factor Dynein_IC2 PF11540.8 CRK36707.1 - 0.19 11.7 0.1 0.6 10.1 0.0 1.9 2 0 0 2 2 2 0 Cytoplasmic dynein 1 intermediate chain 2 Pectate_lyase_3 PF12708.7 CRK36709.1 - 1.3e-90 302.9 11.9 5e-81 271.6 4.7 2.9 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 CRK36709.1 - 8.4e-07 28.6 1.1 0.042 13.5 0.1 2.6 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase TSP_C PF05735.12 CRK36709.1 - 0.0099 15.8 0.3 0.027 14.4 0.3 1.7 1 0 0 1 1 1 1 Thrombospondin C-terminal region Scs3p PF10261.9 CRK36711.1 - 2.1e-74 250.1 3.1 2.8e-74 249.8 3.1 1.1 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM Cation_efflux PF01545.21 CRK36711.1 - 0.0013 18.5 0.1 0.049 13.3 0.3 2.2 2 0 0 2 2 2 1 Cation efflux family Virul_fac_BrkB PF03631.15 CRK36711.1 - 2.2 7.8 17.1 1.7 8.2 3.9 3.0 2 1 1 3 3 3 0 Virulence factor BrkB SP2 PF03014.14 CRK36713.1 - 0.028 12.8 0.3 0.036 12.5 0.3 1.1 1 0 0 1 1 1 0 Structural protein 2 AhpC-TSA_2 PF13911.6 CRK36713.1 - 0.07 13.3 0.1 0.14 12.3 0.1 1.5 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme GlyL_C PF12524.8 CRK36713.1 - 0.097 12.8 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 dsDNA virus glycoprotein L C terminal Myb_DNA-bind_4 PF13837.6 CRK36713.1 - 0.11 12.9 1.5 0.28 11.6 0.8 1.9 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain TAF1D PF15333.6 CRK36713.1 - 0.5 10.1 5.2 0.054 13.2 0.5 1.7 2 0 0 2 2 2 0 TATA box-binding protein-associated factor 1D Man-6-P_recep PF02157.15 CRK36715.1 - 4.2e-16 58.8 0.0 8.2e-15 54.6 0.0 2.3 1 1 1 2 2 2 1 Mannose-6-phosphate receptor ATG27 PF09451.10 CRK36715.1 - 1e-10 42.0 0.0 4e-10 40.0 0.0 2.1 1 1 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 CRK36715.1 - 7.1e-06 26.1 0.1 0.002 18.2 0.0 2.4 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat ERG4_ERG24 PF01222.17 CRK36717.1 - 2e-164 547.5 3.8 2.3e-164 547.3 3.8 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 CRK36717.1 - 0.00017 21.2 1.6 0.00028 20.5 0.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) Glyco_hydro_3_C PF01915.22 CRK36719.1 - 1.6e-49 168.7 0.0 6.3e-48 163.4 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 CRK36719.1 - 7.9e-31 107.6 0.0 1.4e-30 106.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 CRK36719.1 - 1.9e-18 66.3 0.0 3.9e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PALP PF00291.25 CRK36721.1 - 5.7e-58 196.7 0.1 8e-58 196.2 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Aldo_ket_red PF00248.21 CRK36722.1 - 2e-13 50.2 0.3 3.3e-11 42.9 0.3 2.5 1 1 0 1 1 1 1 Aldo/keto reductase family Atg14 PF10186.9 CRK36722.1 - 0.015 14.4 8.6 0.025 13.7 3.1 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 MIP-T3_C PF17749.1 CRK36722.1 - 0.032 14.2 3.7 0.72 9.8 0.0 2.8 2 1 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region Spore_II_R PF09551.10 CRK36722.1 - 0.95 9.9 5.5 0.69 10.4 0.1 2.8 2 1 0 2 2 2 0 Stage II sporulation protein R (spore_II_R) PDDEXK_6 PF04720.12 CRK36722.1 - 3.9 7.4 6.3 6.1 6.7 3.4 2.1 2 0 0 2 2 2 0 PDDEXK-like family of unknown function HET PF06985.11 CRK36723.1 - 9.6e-19 68.2 1.0 2.5e-18 66.8 1.0 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) zf-C3HC4_3 PF13920.6 CRK36724.1 - 3.5e-09 36.4 4.6 3.5e-09 36.4 4.6 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CRK36724.1 - 7.2e-08 32.6 4.5 1.9e-07 31.3 4.5 1.8 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 CRK36724.1 - 1.5e-07 31.2 3.7 7.8e-07 28.9 3.7 2.2 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 CRK36724.1 - 3e-07 30.4 3.8 7.9e-07 29.0 3.8 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CRK36724.1 - 4e-07 29.8 2.9 1e-06 28.5 2.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CRK36724.1 - 1.2e-06 28.3 6.7 1.7e-06 27.9 4.0 2.5 2 1 1 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CRK36724.1 - 7e-06 25.8 1.4 7e-06 25.8 1.4 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CRK36724.1 - 2.9e-05 24.1 3.0 7.8e-05 22.7 3.0 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 CRK36724.1 - 0.018 15.3 1.6 0.049 13.9 1.6 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_14 PF17978.1 CRK36724.1 - 0.33 11.4 2.2 1.5 9.3 0.7 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_4 PF14570.6 CRK36724.1 - 3.4 7.5 10.5 0.35 10.7 4.8 2.4 2 1 0 2 2 1 0 RING/Ubox like zinc-binding domain Fungal_trans_2 PF11951.8 CRK36725.1 - 3.8e-39 134.6 2.2 7e-39 133.7 2.2 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK36725.1 - 0.0086 16.2 2.3 0.015 15.4 2.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FF PF01846.19 CRK36726.1 - 0.13 12.4 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 FF domain CAP_N PF01213.19 CRK36726.1 - 0.39 10.2 2.5 0.66 9.4 2.5 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal FAD_binding_7 PF03441.14 CRK36727.1 - 2.9e-76 255.5 0.3 4.9e-76 254.7 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 CRK36727.1 - 1.2e-22 80.7 0.0 3.9e-22 79.0 0.0 1.8 2 0 0 2 2 2 1 DNA photolyase Velvet PF11754.8 CRK36728.1 - 1.5e-53 182.3 1.0 6e-34 118.1 0.1 3.5 2 2 1 3 3 3 2 Velvet factor PHD20L1_u1 PF16660.5 CRK36728.1 - 0.5 11.1 6.7 1.3 9.8 0.4 2.7 2 0 0 2 2 2 0 PHD finger protein 20-like protein 1 AMP-binding PF00501.28 CRK36729.1 - 7e-63 212.7 0.0 1.1e-33 116.5 0.0 2.3 1 1 1 2 2 2 2 AMP-binding enzyme NAD_binding_4 PF07993.12 CRK36729.1 - 1e-58 198.5 0.0 2e-58 197.6 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein adh_short PF00106.25 CRK36729.1 - 3.7e-50 170.1 5.4 8.2e-50 169.0 3.9 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK36729.1 - 1.2e-36 126.5 1.9 2.7e-36 125.3 1.9 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK36729.1 - 4e-18 66.0 3.6 7.1e-14 52.1 1.7 2.4 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 CRK36729.1 - 3.2e-14 53.0 0.1 1.3e-09 37.9 0.0 3.6 3 1 0 3 3 3 2 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 CRK36729.1 - 6.5e-10 39.2 0.0 1.5e-09 38.1 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 CRK36729.1 - 2e-05 23.8 0.3 0.0021 17.1 0.0 2.9 3 0 0 3 3 3 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 CRK36729.1 - 4.5e-05 22.7 4.9 0.00081 18.6 0.1 3.9 3 1 0 3 3 3 1 RmlD substrate binding domain AMP-binding_C PF13193.6 CRK36729.1 - 0.00021 22.2 0.0 0.00096 20.1 0.0 2.3 2 0 0 2 2 1 1 AMP-binding enzyme C-terminal domain NAD_binding_10 PF13460.6 CRK36729.1 - 0.00028 20.8 0.8 0.0035 17.3 0.5 2.4 2 0 0 2 2 2 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 CRK36729.1 - 0.00071 18.8 2.5 0.31 10.1 0.1 3.2 3 1 0 3 3 3 2 Polysaccharide biosynthesis protein THF_DHG_CYH_C PF02882.19 CRK36729.1 - 0.0024 17.2 1.2 0.0067 15.8 1.2 1.8 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ApbA PF02558.16 CRK36729.1 - 0.069 12.8 0.2 0.15 11.7 0.2 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NmrA PF05368.13 CRK36729.1 - 0.6 9.6 3.2 12 5.3 0.0 2.4 2 0 0 2 2 2 0 NmrA-like family Tyrosinase PF00264.20 CRK36732.1 - 1.8e-41 142.9 2.2 2.3e-41 142.5 2.2 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase ABC_membrane PF00664.23 CRK36733.1 - 8.8e-55 186.3 14.0 1.1e-54 185.9 14.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 CRK36733.1 - 1.5e-47 161.6 0.0 4.1e-32 111.6 0.0 2.8 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 CRK36733.1 - 1.7e-11 44.0 0.0 1.6e-05 24.4 0.0 2.9 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 CRK36733.1 - 9.6e-07 27.9 0.7 0.022 13.6 0.1 2.3 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA PF00004.29 CRK36733.1 - 0.00033 21.1 0.5 3.6 8.0 0.0 3.6 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CRK36733.1 - 0.00086 19.7 0.3 0.0095 16.3 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain SbcCD_C PF13558.6 CRK36733.1 - 0.0012 19.0 2.6 2.7 8.3 0.2 4.1 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 CRK36733.1 - 0.0054 17.0 0.1 0.062 13.6 0.0 2.8 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 CRK36733.1 - 0.0083 16.0 0.0 0.78 9.6 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 CRK36733.1 - 0.068 12.9 0.0 0.64 9.8 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_28 PF13521.6 CRK36733.1 - 0.078 13.2 0.0 0.25 11.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 CRK36733.1 - 0.12 12.3 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_21 PF13304.6 CRK36733.1 - 0.16 11.7 0.5 4.3 7.1 0.1 2.8 2 1 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system Tyrosinase PF00264.20 CRK36734.1 - 5.8e-42 144.5 2.0 7.3e-42 144.2 2.0 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase ABC_membrane PF00664.23 CRK36735.1 - 1.3e-105 353.0 42.8 2.7e-54 184.7 14.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CRK36735.1 - 9.1e-68 227.0 0.0 1e-32 113.5 0.0 2.8 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CRK36735.1 - 4.7e-13 49.1 0.0 0.0012 18.3 0.0 4.0 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CRK36735.1 - 5.2e-07 29.3 1.5 0.0037 17.0 0.3 3.3 3 0 0 3 3 3 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CRK36735.1 - 6.7e-07 29.4 0.0 0.067 13.1 0.0 3.5 3 0 0 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 CRK36735.1 - 6e-06 26.7 3.2 0.019 15.3 0.0 3.2 2 1 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.9 CRK36735.1 - 7.4e-06 25.0 3.4 0.044 12.6 0.1 3.0 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_22 PF13401.6 CRK36735.1 - 2.8e-05 24.4 0.7 0.12 12.7 0.0 3.3 2 2 0 2 2 2 2 AAA domain AAA_15 PF13175.6 CRK36735.1 - 0.00028 20.7 0.1 0.81 9.3 0.0 2.9 3 0 0 3 3 3 2 AAA ATPase domain AAA_25 PF13481.6 CRK36735.1 - 0.0006 19.5 3.0 0.19 11.3 0.1 3.1 3 0 0 3 3 2 2 AAA domain AAA_30 PF13604.6 CRK36735.1 - 0.002 17.9 1.4 3.5 7.3 0.1 3.6 4 0 0 4 4 4 1 AAA domain AAA_21 PF13304.6 CRK36735.1 - 0.0029 17.5 1.0 6.4 6.5 0.0 3.6 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 CRK36735.1 - 0.003 16.9 0.0 3.5 6.8 0.0 2.8 2 0 0 2 2 2 2 Zeta toxin SbcCD_C PF13558.6 CRK36735.1 - 0.0039 17.4 1.8 4.4 7.6 0.2 3.7 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit G-alpha PF00503.20 CRK36735.1 - 0.0043 16.3 0.0 2 7.5 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit AAA_28 PF13521.6 CRK36735.1 - 0.0051 17.1 0.7 0.42 10.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 CRK36735.1 - 0.014 15.4 0.2 6.8 6.7 0.0 3.0 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 CRK36735.1 - 0.019 15.5 0.0 7.3 7.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CRK36735.1 - 0.021 14.3 0.0 8.4 5.9 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_33 PF13671.6 CRK36735.1 - 0.028 14.6 0.0 12 6.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 CRK36735.1 - 0.038 14.1 2.2 6.2 6.8 0.1 2.8 3 0 0 3 3 2 0 Helicase HerA, central domain SRP54 PF00448.22 CRK36735.1 - 0.04 13.6 0.2 2.9 7.5 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain PRK PF00485.18 CRK36735.1 - 0.043 13.5 0.0 2.6 7.7 0.0 2.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_23 PF13476.6 CRK36735.1 - 0.06 13.8 0.4 4.3 7.8 0.1 2.6 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 CRK36735.1 - 0.064 12.9 0.0 5.2 6.7 0.0 2.6 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain RNA_helicase PF00910.22 CRK36735.1 - 0.084 13.3 0.0 13 6.2 0.0 3.2 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 CRK36735.1 - 0.085 12.6 0.0 7 6.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 CRK36735.1 - 0.11 12.5 0.1 0.51 10.2 0.0 2.0 2 0 0 2 2 2 0 Rad17 P-loop domain APS_kinase PF01583.20 CRK36735.1 - 0.12 12.2 0.1 3.1 7.7 0.0 2.8 2 0 0 2 2 2 0 Adenylylsulphate kinase MMR_HSR1 PF01926.23 CRK36735.1 - 2.4 8.2 4.6 19 5.4 0.0 3.3 3 0 0 3 3 3 0 50S ribosome-binding GTPase SARAF PF06682.12 CRK36737.1 - 5.1e-52 177.6 20.5 1.7e-32 113.4 0.0 2.0 1 1 1 2 2 2 2 SOCE-associated regulatory factor of calcium homoeostasis ABC_membrane PF00664.23 CRK36738.1 - 2.4e-43 148.8 11.7 4.4e-43 147.9 11.7 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region BRE1 PF08647.11 CRK36738.1 - 2.2e-21 75.7 8.1 2.2e-21 75.7 8.1 5.9 5 1 1 6 6 4 1 BRE1 E3 ubiquitin ligase zf-C3HC4_3 PF13920.6 CRK36738.1 - 1.2e-08 34.7 6.9 1.8e-08 34.1 6.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CRK36738.1 - 3.8e-08 33.1 9.6 6.7e-08 32.3 9.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CRK36738.1 - 7.7e-08 32.1 6.9 1.3e-07 31.4 6.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 CRK36738.1 - 1.4e-07 31.5 5.4 2.6e-07 30.5 5.4 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CRK36738.1 - 1.6e-07 31.0 9.0 2.7e-07 30.3 9.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CRK36738.1 - 7.3e-07 29.1 8.7 1.2e-06 28.4 8.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 CRK36738.1 - 3.1e-06 27.4 8.1 5.1e-06 26.7 8.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 CRK36738.1 - 0.0002 21.4 6.9 0.00038 20.6 6.9 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING JIP_LZII PF16471.5 CRK36738.1 - 0.0017 18.5 0.9 0.0017 18.5 0.9 6.3 6 1 0 6 6 6 1 JNK-interacting protein leucine zipper II DivIC PF04977.15 CRK36738.1 - 0.0044 16.8 2.4 0.0044 16.8 2.4 9.3 4 3 3 9 9 8 2 Septum formation initiator zf-rbx1 PF12678.7 CRK36738.1 - 0.0099 16.2 6.3 0.036 14.4 6.3 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 CRK36738.1 - 0.017 15.0 3.4 0.034 14.0 3.4 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-UDP PF14569.6 CRK36738.1 - 0.029 14.5 2.8 0.065 13.4 2.8 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger TetR PF13972.6 CRK36738.1 - 0.11 12.3 0.0 0.11 12.3 0.0 3.4 4 0 0 4 4 4 0 Bacterial transcriptional repressor PKcGMP_CC PF16808.5 CRK36738.1 - 0.12 12.2 4.8 1.6 8.7 0.4 4.2 4 0 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase zf-RING_4 PF14570.6 CRK36738.1 - 0.18 11.6 6.2 0.78 9.6 6.4 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain DZR PF12773.7 CRK36738.1 - 3 8.0 5.7 5.6 7.1 5.7 1.4 1 0 0 1 1 1 0 Double zinc ribbon zf-C2H2_9 PF16293.5 CRK36738.1 - 3.7 7.5 4.9 9.3 6.2 0.2 3.1 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) Pox_A_type_inc PF04508.12 CRK36738.1 - 8.3 6.4 6.6 68 3.6 0.2 4.2 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat BRE1 PF08647.11 CRK36740.1 - 1.6e-21 76.2 8.1 1.6e-21 76.2 8.1 6.6 5 1 1 6 6 5 1 BRE1 E3 ubiquitin ligase zf-C3HC4_3 PF13920.6 CRK36740.1 - 9.4e-09 35.0 6.9 1.4e-08 34.4 6.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CRK36740.1 - 3e-08 33.4 9.6 5.2e-08 32.6 9.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CRK36740.1 - 6e-08 32.4 6.9 1e-07 31.7 6.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 CRK36740.1 - 9.8e-08 31.9 5.4 2.1e-07 30.9 5.4 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CRK36740.1 - 1.2e-07 31.4 9.0 2.1e-07 30.6 9.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CRK36740.1 - 5.6e-07 29.4 8.7 9.3e-07 28.7 8.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 CRK36740.1 - 2.4e-06 27.8 8.1 4e-06 27.1 8.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 CRK36740.1 - 0.00015 21.8 6.9 0.00029 20.9 6.9 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING JIP_LZII PF16471.5 CRK36740.1 - 0.0014 18.8 0.8 0.0014 18.8 0.8 7.0 6 2 1 7 7 7 1 JNK-interacting protein leucine zipper II zf-rbx1 PF12678.7 CRK36740.1 - 0.0062 16.8 6.2 0.025 14.8 6.2 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain DivIC PF04977.15 CRK36740.1 - 0.01 15.6 1.4 0.01 15.6 1.4 9.5 5 3 5 11 11 11 0 Septum formation initiator zf-RING_6 PF14835.6 CRK36740.1 - 0.014 15.3 3.4 0.026 14.4 3.4 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-UDP PF14569.6 CRK36740.1 - 0.022 14.9 2.8 0.05 13.7 2.8 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger bZIP_1 PF00170.21 CRK36740.1 - 0.056 13.6 0.6 0.056 13.6 0.6 9.5 7 3 2 10 10 10 0 bZIP transcription factor TetR PF13972.6 CRK36740.1 - 0.085 12.6 0.0 0.085 12.6 0.0 4.0 4 1 0 4 4 4 0 Bacterial transcriptional repressor zf-RING_4 PF14570.6 CRK36740.1 - 0.14 12.0 6.3 0.7 9.7 6.6 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain PKcGMP_CC PF16808.5 CRK36740.1 - 0.26 11.2 9.6 1.2 9.0 0.4 5.1 6 0 0 6 6 5 0 Coiled-coil N-terminus of cGMP-dependent protein kinase zf-C2H2_9 PF16293.5 CRK36740.1 - 2.1 8.2 4.9 7.4 6.5 0.2 3.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) DZR PF12773.7 CRK36740.1 - 2.3 8.3 5.7 4.3 7.4 5.7 1.4 1 0 0 1 1 1 0 Double zinc ribbon Pox_A_type_inc PF04508.12 CRK36740.1 - 3.5 7.7 6.6 54 3.9 0.2 4.4 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat zf-C2H2 PF00096.26 CRK36740.1 - 6.1 7.5 9.1 0.69 10.5 1.1 3.2 3 0 0 3 3 2 0 Zinc finger, C2H2 type Myb_DNA-bind_7 PF15963.5 CRK36743.1 - 1.3e-23 82.6 0.4 1.3e-23 82.6 0.4 2.1 2 0 0 2 2 2 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 CRK36743.1 - 3.9e-06 27.0 0.0 7.8e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CRK36743.1 - 0.00035 20.8 0.1 0.0007 19.8 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain UBA PF00627.31 CRK36744.1 - 3.7e-25 87.4 7.0 1.3e-13 50.5 0.5 2.8 2 1 1 3 3 3 2 UBA/TS-N domain XPC-binding PF09280.11 CRK36744.1 - 1.6e-24 85.4 13.9 2.6e-24 84.7 13.9 1.3 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.23 CRK36744.1 - 5.4e-21 74.1 0.6 1e-20 73.3 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CRK36744.1 - 1.4e-08 34.4 0.8 2.5e-08 33.6 0.8 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.10 CRK36744.1 - 0.00035 20.3 0.0 0.38 10.6 0.0 2.4 2 0 0 2 2 2 2 Fungal ubiquitin-associated domain Rad60-SLD_2 PF13881.6 CRK36744.1 - 0.016 15.3 0.0 0.033 14.3 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Clathrin_H_link PF13838.6 CRK36744.1 - 0.025 14.5 0.6 0.088 12.7 0.3 2.2 2 0 0 2 2 2 0 Clathrin-H-link DUF2407 PF10302.9 CRK36744.1 - 0.029 14.9 0.0 0.06 13.9 0.0 1.5 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain MCM_N PF14551.6 CRK36744.1 - 0.032 14.8 0.0 0.079 13.5 0.0 1.6 1 0 0 1 1 1 0 MCM N-terminal domain Ubiquitin_5 PF18037.1 CRK36744.1 - 0.065 13.6 0.2 0.12 12.7 0.2 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain DUF2776 PF10951.8 CRK36745.1 - 0.0016 17.8 6.6 0.0023 17.3 6.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2776) DAP10 PF07213.11 CRK36745.1 - 6.3 6.8 7.2 0.22 11.5 0.7 1.9 2 0 0 2 2 2 0 DAP10 membrane protein Arg_decarb_HB PF17810.1 CRK36746.1 - 0.049 13.9 0.0 0.054 13.8 0.0 1.1 1 0 0 1 1 1 0 Arginine decarboxylase helical bundle domain XPC-binding PF09280.11 CRK36747.1 - 4e-24 84.1 13.9 7e-24 83.3 13.9 1.4 1 0 0 1 1 1 1 XPC-binding domain UBA PF00627.31 CRK36747.1 - 5.2e-24 83.7 7.8 3.3e-13 49.2 0.5 2.6 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.23 CRK36747.1 - 4.4e-21 74.4 1.0 8.3e-21 73.5 1.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CRK36747.1 - 1.2e-08 34.6 1.0 2.3e-08 33.7 1.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.10 CRK36747.1 - 0.0021 17.8 0.0 0.92 9.4 0.0 2.4 2 0 0 2 2 2 2 Fungal ubiquitin-associated domain Rad60-SLD_2 PF13881.6 CRK36747.1 - 0.025 14.7 0.0 0.064 13.4 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 CRK36747.1 - 0.04 14.5 0.0 0.094 13.3 0.0 1.6 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_5 PF18037.1 CRK36747.1 - 0.058 13.7 0.3 0.11 12.8 0.3 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain Clathrin_H_link PF13838.6 CRK36747.1 - 0.064 13.2 0.2 0.23 11.4 0.2 2.0 1 0 0 1 1 1 0 Clathrin-H-link MCM_N PF14551.6 CRK36747.1 - 0.093 13.3 0.0 0.23 12.1 0.0 1.6 1 0 0 1 1 1 0 MCM N-terminal domain DAP10 PF07213.11 CRK36747.1 - 0.12 12.3 0.7 0.47 10.4 0.7 2.0 1 0 0 1 1 1 0 DAP10 membrane protein Acyltransferase PF01553.21 CRK36750.1 - 3.2e-33 114.2 0.0 5e-33 113.6 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase DUF2347 PF09804.9 CRK36752.1 - 2.1e-104 349.1 0.0 3.1e-104 348.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.6 CRK36752.1 - 1.2e-65 221.6 0.1 1.7e-65 221.0 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4484) SPA PF08616.10 CRK36752.1 - 0.00051 20.0 0.0 0.0018 18.2 0.0 1.8 1 1 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 CRK36752.1 - 0.014 14.1 0.1 0.2 10.3 0.0 2.3 3 0 0 3 3 3 0 Transport protein Avl9 NOA36 PF06524.12 CRK36752.1 - 0.64 9.3 2.7 1 8.7 2.7 1.2 1 0 0 1 1 1 0 NOA36 protein FAD_binding_4 PF01565.23 CRK36755.1 - 4e-23 81.7 0.5 7.8e-23 80.8 0.5 1.5 1 0 0 1 1 1 1 FAD binding domain Xpo1 PF08389.12 CRK36756.1 - 3.8e-36 124.4 0.4 1.6e-34 119.1 0.0 3.7 2 1 0 2 2 2 1 Exportin 1-like protein HEAT PF02985.22 CRK36756.1 - 0.0053 16.9 0.0 11 6.6 0.0 4.7 4 0 0 4 4 4 1 HEAT repeat SHR3_chaperone PF08229.11 CRK36756.1 - 0.0098 14.9 0.0 3.5 6.6 0.0 3.0 3 0 0 3 3 3 2 ER membrane protein SH3 DUF896 PF05979.12 CRK36756.1 - 0.087 12.7 0.5 22 5.0 0.1 2.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) RTA1 PF04479.13 CRK36759.1 - 1.4e-61 207.7 11.7 1.4e-61 207.7 11.7 1.4 2 0 0 2 2 2 1 RTA1 like protein DUF2633 PF11119.8 CRK36759.1 - 0.6 10.1 3.6 5.9 6.9 0.3 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2633) Whi5 PF08528.11 CRK36760.1 - 1.1e-09 37.7 0.1 1.7e-09 37.1 0.1 1.3 1 0 0 1 1 1 1 Whi5 like SET PF00856.28 CRK36761.1 - 0.75 10.2 7.4 6.9 7.0 0.2 3.4 3 0 0 3 3 3 0 SET domain DUF3446 PF11928.8 CRK36763.1 - 0.024 14.9 0.1 0.031 14.6 0.1 1.3 1 0 0 1 1 1 0 Early growth response N-terminal domain Peptidase_M18 PF02127.15 CRK36764.1 - 4e-173 576.2 0.0 7.5e-172 572.0 0.0 2.0 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 CRK36764.1 - 1.7e-06 27.3 0.0 0.0082 15.2 0.0 3.0 2 1 1 3 3 3 3 M42 glutamyl aminopeptidase AdoHcyase PF05221.17 CRK36765.1 - 7.5e-15 54.9 0.0 8.6e-15 54.7 0.0 1.2 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 CRK36765.1 - 3e-06 27.4 0.1 4e-06 27.0 0.1 1.2 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Sel1 PF08238.12 CRK36768.1 - 5.4e-05 23.7 0.1 0.0098 16.5 0.1 2.2 2 0 0 2 2 2 2 Sel1 repeat Myb_DNA-bind_7 PF15963.5 CRK36772.1 - 7e-25 86.7 0.6 1.4e-24 85.8 0.6 1.4 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 CRK36772.1 - 5e-07 29.8 0.0 1.2e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CRK36772.1 - 4.3e-05 23.7 0.0 8e-05 22.8 0.0 1.6 1 1 0 1 1 1 1 Myb-like DNA-binding domain ABC_membrane PF00664.23 CRK36773.1 - 9.9e-22 77.9 3.8 1.1e-21 77.8 3.8 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region DUF2852 PF11014.8 CRK36773.1 - 0.04 14.1 0.5 0.049 13.8 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) Cu_bind_CorA PF18252.1 CRK36773.1 - 0.054 13.1 0.1 0.067 12.8 0.1 1.1 1 0 0 1 1 1 0 Copper(I)-binding protein CorA DUF3742 PF12553.8 CRK36773.1 - 0.12 12.5 0.4 0.14 12.3 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3742) Gram_pos_anchor PF00746.21 CRK36773.1 - 4.2 7.4 5.9 9.8 6.2 1.1 2.2 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Cas9-BH PF16593.5 CRK36775.1 - 0.046 13.5 6.2 0.05 13.3 6.2 1.1 1 0 0 1 1 1 0 Bridge helix of CRISPR-associated endonuclease Cas9 Methyltransf_23 PF13489.6 CRK36778.1 - 1.5e-06 28.1 0.0 1.6e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK36778.1 - 3.1e-06 27.8 0.0 4.1e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK36778.1 - 0.0002 21.2 0.0 0.00026 20.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 CRK36778.1 - 0.0005 20.2 0.0 0.00051 20.2 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_11 PF08241.12 CRK36778.1 - 0.00097 19.7 0.0 0.0013 19.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK36778.1 - 0.0013 19.5 0.0 0.002 18.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CRK36778.1 - 0.0022 17.6 0.0 0.0027 17.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 CRK36778.1 - 0.016 14.5 0.0 0.021 14.2 0.0 1.1 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_4 PF02390.17 CRK36778.1 - 0.027 13.9 0.0 0.034 13.6 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.13 CRK36778.1 - 0.11 11.9 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 CRK36778.1 - 0.18 11.1 0.0 0.2 10.9 0.0 1.0 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Xan_ur_permease PF00860.20 CRK36779.1 - 0.034 12.8 0.2 0.034 12.8 0.2 1.1 1 0 0 1 1 1 0 Permease family Chitin_synth_2 PF03142.15 CRK36780.1 - 6.2e-54 183.5 0.2 6.7e-54 183.4 0.2 1.0 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 CRK36780.1 - 9.4e-06 25.7 0.0 1.1e-05 25.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 CRK36780.1 - 4.7e-05 23.4 0.0 4.7e-05 23.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 CRK36780.1 - 0.00064 19.2 0.0 0.00067 19.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 CRK36780.1 - 0.0068 16.2 0.0 0.0073 16.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Mg_trans_NIPA PF05653.14 CRK36781.1 - 2.6e-38 131.8 9.4 3.8e-38 131.3 9.4 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA eIF-1a PF01176.19 CRK36781.1 - 2.9e-19 68.6 0.0 6e-19 67.6 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 DUF5373 PF17343.2 CRK36781.1 - 0.47 10.3 4.7 0.87 9.4 4.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5373) DUF2157 PF09925.9 CRK36781.1 - 3.5 7.4 7.0 0.63 9.8 2.4 1.9 1 1 0 2 2 2 0 Predicted membrane protein (DUF2157) Sec63 PF02889.16 CRK36786.1 - 1.1e-10 41.1 0.2 1.4e-10 40.7 0.2 1.1 1 0 0 1 1 1 1 Sec63 Brl domain Nucleoporin_C PF03177.14 CRK36789.1 - 1.4e-51 176.0 3.4 1.7e-51 175.7 3.4 1.0 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Adap_comp_sub PF00928.21 CRK36790.1 - 3.2e-24 85.7 0.0 4.1e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family tRNA_m1G_MT PF01746.21 CRK36791.1 - 7.4e-06 25.8 0.0 9.1e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase Fungal_trans PF04082.18 CRK36795.1 - 5.7e-23 81.3 0.1 7.2e-23 81.0 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Haem_oxygenas_2 PF14518.6 CRK36795.1 - 0.00043 20.1 0.2 0.00064 19.5 0.2 1.2 1 0 0 1 1 1 1 Iron-containing redox enzyme ABC2_membrane PF01061.24 CRK36796.1 - 1.6e-16 60.4 0.5 1.7e-16 60.3 0.5 1.0 1 0 0 1 1 1 1 ABC-2 type transporter PITH PF06201.13 CRK36798.1 - 1.7e-13 51.1 0.0 1.8e-13 51.0 0.0 1.0 1 0 0 1 1 1 1 PITH domain ADH_N_2 PF16884.5 CRK36800.1 - 6.4e-18 64.6 0.0 7.4e-18 64.4 0.0 1.1 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase DUF4981 PF16353.5 CRK36811.1 - 0.022 15.2 0.0 0.034 14.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function(DUF4981) MCRS_N PF13325.6 CRK36816.1 - 0.17 11.9 2.3 0.24 11.4 2.3 1.2 1 0 0 1 1 1 0 N-terminal region of micro-spherule protein MKT1_N PF12247.8 CRK36818.1 - 1.2e-08 35.2 0.1 2.2e-08 34.3 0.1 1.5 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication Pkinase PF00069.25 CRK36819.1 - 2.2e-21 76.4 0.0 3.1e-21 75.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK36819.1 - 7.1e-07 28.8 0.0 1e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase TAF1D PF15333.6 CRK36822.1 - 0.036 13.8 2.0 0.038 13.7 2.0 1.0 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D DEAD PF00270.29 CRK36823.1 - 2.2e-10 40.6 0.0 2.3e-10 40.5 0.0 1.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase GARS_N PF02844.15 CRK36823.1 - 0.052 14.3 0.0 0.059 14.2 0.0 1.1 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain ResIII PF04851.15 CRK36823.1 - 0.12 12.3 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit MOR2-PAG1_N PF14222.6 CRK36825.1 - 2.9e-25 89.3 0.0 3.1e-25 89.1 0.0 1.0 1 0 0 1 1 1 1 Cell morphogenesis N-terminal Exo_endo_phos PF03372.23 CRK36827.1 - 0.0015 18.1 0.0 0.0015 18.1 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family FMN_red PF03358.15 CRK36828.1 - 1.3e-05 25.0 0.0 1.4e-05 24.9 0.0 1.0 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 CRK36828.1 - 0.0079 15.9 0.1 0.0093 15.7 0.1 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_5 PF12724.7 CRK36828.1 - 0.21 11.9 0.0 0.25 11.6 0.0 1.1 1 0 0 1 1 1 0 Flavodoxin domain DCP1 PF06058.13 CRK36830.1 - 0.065 13.2 0.0 0.068 13.1 0.0 1.2 1 0 0 1 1 1 0 Dcp1-like decapping family Polysacc_deac_1 PF01522.21 CRK36831.1 - 0.00055 19.8 0.1 0.00055 19.8 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase aGPT-Pplase3 PF18746.1 CRK36831.1 - 0.03 13.7 0.8 0.037 13.4 0.8 1.1 1 0 0 1 1 1 0 Alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 3 Pro_isomerase PF00160.21 CRK36837.1 - 1.2e-24 87.4 0.1 1.3e-24 87.3 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD UNC45-central PF11701.8 CRK36841.1 - 1.1e-27 96.9 0.0 1.2e-27 96.7 0.0 1.0 1 0 0 1 1 1 1 Myosin-binding striated muscle assembly central Adap_comp_sub PF00928.21 CRK36842.1 - 8.6e-21 74.5 0.1 9.4e-21 74.4 0.1 1.0 1 0 0 1 1 1 1 Adaptor complexes medium subunit family muHD PF10291.9 CRK36842.1 - 0.099 12.1 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain Sec1 PF00995.23 CRK36843.1 - 2.7e-11 43.4 0.0 2.7e-11 43.4 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Q_salvage PF10343.9 CRK36844.1 - 1.4e-29 103.6 0.1 1.6e-29 103.4 0.1 1.0 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family Mem_trans PF03547.18 CRK36846.1 - 2.5e-08 32.7 0.5 2.8e-08 32.6 0.5 1.0 1 0 0 1 1 1 1 Membrane transport protein UPF0052 PF01933.18 CRK36848.1 - 4.3e-60 203.4 0.0 5.5e-60 203.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 CFEM PF05730.11 CRK36849.1 - 1.8e-09 37.5 11.4 3.2e-09 36.7 11.4 1.4 1 0 0 1 1 1 1 CFEM domain Glyco_hydro_64 PF16483.5 CRK36851.1 - 2.6e-116 388.9 0.0 3e-116 388.7 0.0 1.0 1 0 0 1 1 1 1 Beta-1,3-glucanase FA_desaturase PF00487.24 CRK36852.1 - 3.7e-26 92.5 23.8 7.1e-26 91.6 23.8 1.4 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 CRK36852.1 - 1.6e-05 25.1 0.0 2.9e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) LIDHydrolase PF10230.9 CRK36853.1 - 4.9e-57 193.5 0.0 5.7e-57 193.3 0.0 1.0 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 CRK36853.1 - 1e-05 26.3 7.6 1.3e-05 26.0 7.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CRK36853.1 - 0.0075 15.6 0.1 0.054 12.8 0.1 2.3 3 0 0 3 3 3 1 Serine aminopeptidase, S33 AA_permease PF00324.21 CRK36854.1 - 1.7e-128 429.2 32.3 2.1e-128 429.0 32.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CRK36854.1 - 4e-43 147.8 36.3 5e-43 147.5 36.3 1.1 1 0 0 1 1 1 1 Amino acid permease Na_Ala_symp PF01235.17 CRK36854.1 - 6.9 5.9 18.0 1.1 8.5 9.2 2.6 2 0 0 2 2 2 0 Sodium:alanine symporter family adh_short_C2 PF13561.6 CRK36855.1 - 8.6e-31 107.3 0.1 1.2e-30 106.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRK36855.1 - 3.6e-24 85.3 0.1 4.5e-24 85.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CRK36855.1 - 7.2e-05 22.8 0.4 9.5e-05 22.4 0.4 1.2 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 CRK36855.1 - 0.00052 19.4 0.0 0.00091 18.6 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Oxidored_nitro PF00148.19 CRK36855.1 - 0.0032 16.3 0.0 0.0042 15.9 0.0 1.1 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase NAD_binding_7 PF13241.6 CRK36855.1 - 0.01 16.2 0.0 0.018 15.5 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 CRK36855.1 - 0.033 14.1 0.1 0.048 13.5 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 CRK36855.1 - 0.052 13.8 0.1 0.087 13.1 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain AdoHcyase_NAD PF00670.21 CRK36855.1 - 0.062 13.4 0.1 0.1 12.7 0.1 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain TrkA_N PF02254.18 CRK36855.1 - 0.083 13.2 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain GDP_Man_Dehyd PF16363.5 CRK36855.1 - 0.099 12.0 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase AA_permease_2 PF13520.6 CRK36856.1 - 2.4e-107 359.4 38.6 3.6e-69 233.6 17.0 3.1 2 1 1 3 3 3 2 Amino acid permease DUF3311 PF11755.8 CRK36856.1 - 0.61 10.1 5.3 1.1 9.2 0.0 4.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3311) Peptidase_S8 PF00082.22 CRK36857.1 - 0.0079 15.5 0.0 0.0082 15.4 0.0 1.1 1 0 0 1 1 1 1 Subtilase family AA_permease PF00324.21 CRK36858.1 - 5.7e-136 453.9 34.5 6.6e-136 453.7 34.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CRK36858.1 - 1.2e-35 123.3 35.4 1.4e-35 122.9 35.4 1.0 1 0 0 1 1 1 1 Amino acid permease AnmK PF03702.14 CRK36859.1 - 2e-85 287.1 0.0 2.4e-85 286.8 0.0 1.0 1 0 0 1 1 1 1 Anhydro-N-acetylmuramic acid kinase Maf_N PF08383.11 CRK36859.1 - 0.0053 16.5 0.8 0.44 10.4 0.1 3.3 4 0 0 4 4 4 1 Maf N-terminal region DUF768 PF05589.11 CRK36859.1 - 0.043 13.8 0.0 0.093 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF768) Sugar_tr PF00083.24 CRK36860.1 - 4.4e-58 197.2 3.9 5e-58 197.0 3.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK36860.1 - 1.4e-13 50.5 34.9 2.9e-10 39.6 13.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Claudin_2 PF13903.6 CRK36860.1 - 0.41 10.4 8.0 0.058 13.2 1.7 2.5 1 1 2 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction Fungal_trans PF04082.18 CRK36861.1 - 3.3e-09 36.2 0.1 4.8e-09 35.6 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK36861.1 - 1.1e-05 25.5 11.0 1.8e-05 24.8 11.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fasciclin PF02469.22 CRK36862.1 - 4.8e-44 149.7 0.3 1.8e-25 89.6 0.1 2.1 2 0 0 2 2 2 2 Fasciclin domain BAR PF03114.18 CRK36864.1 - 3.5e-50 170.9 3.4 4.3e-50 170.6 3.4 1.1 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 CRK36864.1 - 1.8e-07 30.6 1.6 2.4e-07 30.2 1.6 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking DinB_2 PF12867.7 CRK36864.1 - 0.13 12.7 1.4 16 6.0 1.8 3.0 2 1 0 2 2 2 0 DinB superfamily DUF4510 PF14971.6 CRK36864.1 - 1 9.7 5.0 3 8.2 1.0 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4510) PLDc_2 PF13091.6 CRK36865.1 - 1.3e-20 73.7 0.0 5.3e-15 55.5 0.0 2.8 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 CRK36865.1 - 0.0053 16.9 0.0 6.7 7.1 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif Ytp1 PF10355.9 CRK36866.1 - 1.3e-66 224.7 20.4 1.3e-66 224.7 20.4 2.6 2 1 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 CRK36866.1 - 9.2e-33 112.2 2.6 9.2e-33 112.2 2.6 2.7 4 0 0 4 4 4 1 Domain of unknown function (DUF2427) Cytochrom_B561 PF03188.16 CRK36866.1 - 0.0073 16.4 7.4 0.0073 16.4 7.4 3.6 4 2 0 4 4 4 1 Eukaryotic cytochrome b561 DUF3464 PF11947.8 CRK36866.1 - 0.11 12.3 0.6 0.32 10.7 0.6 1.8 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Glyco_transf_34 PF05637.12 CRK36867.1 - 5.8e-17 62.2 0.1 1.4e-16 60.9 0.1 1.6 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Sporozoite_P67 PF05642.11 CRK36868.1 - 0.085 10.9 3.6 0.082 11.0 3.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDC45 PF02724.14 CRK36868.1 - 1.1 7.5 8.0 1.1 7.5 8.0 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF913 PF06025.12 CRK36868.1 - 1.5 7.8 5.9 1.5 7.7 5.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) GAGA_bind PF06217.12 CRK36868.1 - 1.7 8.9 7.9 2.2 8.5 7.9 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Ammonium_transp PF00909.21 CRK36870.1 - 3.9e-112 374.9 26.9 4.5e-112 374.7 26.9 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family adh_short_C2 PF13561.6 CRK36871.1 - 3.5e-62 210.0 2.2 3.9e-62 209.8 2.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRK36871.1 - 8.6e-47 159.1 1.0 1e-46 158.9 1.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CRK36871.1 - 1.2e-13 51.3 2.0 1.7e-13 50.9 2.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CRK36871.1 - 0.019 14.4 0.2 0.029 13.8 0.2 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family MDM31_MDM32 PF08118.11 CRK36871.1 - 0.1 11.3 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins MFS_1 PF07690.16 CRK36872.1 - 6.4e-34 117.4 24.9 9.2e-34 116.9 24.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 CRK36872.1 - 3.6e-05 23.2 3.0 3.6e-05 23.2 3.0 2.0 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB AA_permease_2 PF13520.6 CRK36873.1 - 1.4e-24 86.7 15.2 1.2e-22 80.4 15.2 2.0 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CRK36873.1 - 1.4e-14 53.6 2.5 1.4e-14 53.6 2.5 2.0 1 1 1 2 2 2 1 Amino acid permease CTP_synth_N PF06418.14 CRK36874.1 - 2e-125 417.4 0.3 3e-125 416.9 0.1 1.3 2 0 0 2 2 2 1 CTP synthase N-terminus GATase PF00117.28 CRK36874.1 - 1.8e-27 96.3 0.0 3.1e-27 95.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CbiA PF01656.23 CRK36874.1 - 0.016 15.2 0.0 0.028 14.5 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Epimerase PF01370.21 CRK36877.1 - 2e-05 24.2 0.2 0.18 11.2 0.0 2.2 1 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 CRK36877.1 - 0.00026 20.2 0.0 0.00053 19.2 0.0 1.5 2 0 0 2 2 2 1 Male sterility protein NmrA PF05368.13 CRK36877.1 - 0.06 12.9 0.0 0.15 11.6 0.0 1.7 2 0 0 2 2 2 0 NmrA-like family p450 PF00067.22 CRK36878.1 - 2.3e-58 198.1 0.0 2.8e-58 197.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.6 CRK36879.1 - 1.1e-14 54.7 0.0 2e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK36879.1 - 0.0039 17.9 0.0 6 7.6 0.0 3.5 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 CRK36879.1 - 0.039 14.7 0.0 0.87 10.4 0.0 2.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 CRK36879.1 - 0.043 13.6 0.0 0.51 10.1 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.18 CRK36879.1 - 0.043 13.1 0.0 0.49 9.7 0.0 2.3 3 0 0 3 3 3 0 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 CRK36879.1 - 0.06 14.0 0.0 1 10.1 0.0 2.7 1 1 0 1 1 1 0 Methyltransferase domain DUF442 PF04273.13 CRK36880.1 - 0.02 15.0 0.1 1.3 9.1 0.0 2.5 2 0 0 2 2 2 0 Putative phosphatase (DUF442) CSN7a_helixI PF18392.1 CRK36880.1 - 0.074 13.0 0.1 0.22 11.5 0.1 1.8 1 0 0 1 1 1 0 COP9 signalosome complex subunit 7a helix I domain DUF713 PF05218.14 CRK36880.1 - 0.13 12.0 0.1 0.32 10.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF713) Pkinase PF00069.25 CRK36881.1 - 5.2e-14 52.2 0.0 9e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK36881.1 - 0.00048 19.5 0.0 0.00081 18.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EMC3_TMCO1 PF01956.16 CRK36882.1 - 0.025 14.3 1.0 0.044 13.5 1.0 1.4 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like NAD_binding_8 PF13450.6 CRK36883.1 - 2.4e-10 40.5 0.1 5.5e-10 39.3 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 CRK36883.1 - 3e-06 26.9 0.4 5.8e-06 25.9 0.2 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 CRK36883.1 - 8.7e-06 25.3 0.0 4.5e-05 22.9 0.0 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 CRK36883.1 - 1.8e-05 24.1 2.1 2.8e-05 23.4 2.1 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 CRK36883.1 - 8.4e-05 21.4 0.5 0.00012 20.9 0.5 1.2 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 CRK36883.1 - 0.00038 20.2 1.0 0.00099 18.8 1.0 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 CRK36883.1 - 0.0011 18.3 0.3 0.0018 17.6 0.3 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 CRK36883.1 - 0.0012 19.4 0.3 0.009 16.5 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CRK36883.1 - 0.0044 16.3 0.2 0.008 15.4 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CRK36883.1 - 0.044 13.0 0.0 0.073 12.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CRK36883.1 - 0.045 13.0 0.7 0.11 11.7 0.3 1.7 2 0 0 2 2 2 0 FAD binding domain Ribosomal_60s PF00428.19 CRK36885.1 - 0.0015 19.1 8.2 0.0015 19.1 8.2 2.7 3 0 0 3 3 3 1 60s Acidic ribosomal protein PRCC PF10253.9 CRK36885.1 - 2.1 9.1 31.2 1.9 9.2 0.5 2.2 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting DUF913 PF06025.12 CRK36885.1 - 2.9 6.8 16.0 0.15 11.0 0.5 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) FKBP_C PF00254.28 CRK36890.1 - 8.9e-29 99.7 0.0 1.8e-28 98.7 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase RRF PF01765.19 CRK36890.1 - 0.023 14.7 1.7 0.034 14.1 1.7 1.2 1 0 0 1 1 1 0 Ribosome recycling factor Arylsulfotran_2 PF14269.6 CRK36893.1 - 6.1e-32 111.2 0.1 1e-20 74.3 0.0 2.2 1 1 1 2 2 2 2 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 CRK36893.1 - 0.00024 20.1 0.0 0.018 14.0 0.0 2.4 1 1 1 2 2 2 2 Arylsulfotransferase (ASST) LysE PF01810.18 CRK36896.1 - 0.0093 15.4 0.9 0.0093 15.4 0.9 1.8 2 0 0 2 2 2 1 LysE type translocator p450 PF00067.22 CRK36898.1 - 1.1e-62 212.3 0.0 1.5e-62 211.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FA_desaturase PF00487.24 CRK36900.1 - 3.5e-31 108.9 21.0 5.1e-31 108.4 21.0 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 CRK36900.1 - 2e-09 37.5 0.0 4.4e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Gpr1_Fun34_YaaH PF01184.19 CRK36902.1 - 1.2e-87 292.8 16.0 1.6e-87 292.4 16.0 1.2 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family IMS PF00817.20 CRK36902.1 - 2.7e-41 141.1 0.2 4.9e-41 140.2 0.2 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 CRK36902.1 - 2.5e-12 47.5 0.2 6e-12 46.3 0.2 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 CRK36902.1 - 0.0037 17.5 0.0 0.0082 16.4 0.0 1.6 1 0 0 1 1 1 1 IMS family HHH motif DUF919 PF06034.11 CRK36902.1 - 0.056 13.3 4.7 3.9 7.4 0.1 2.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Rep_fac_C PF08542.11 CRK36902.1 - 0.064 13.7 0.1 0.14 12.6 0.1 1.6 1 0 0 1 1 1 0 Replication factor C C-terminal domain FAD_binding_2 PF00890.24 CRK36903.1 - 5.3e-62 210.2 17.4 6.7e-62 209.9 17.4 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 CRK36903.1 - 3.2e-10 40.1 8.5 4.9e-10 39.5 8.5 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CRK36903.1 - 6.1e-08 32.8 3.7 6.3e-08 32.7 1.2 2.4 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 CRK36903.1 - 3.8e-07 29.8 5.0 2.4e-06 27.2 5.0 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CRK36903.1 - 7.5e-06 25.4 1.5 1.7e-05 24.2 1.5 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CRK36903.1 - 1.6e-05 24.4 4.5 3.8e-05 23.1 4.5 1.6 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 CRK36903.1 - 0.00011 22.7 0.4 0.083 13.5 0.8 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CRK36903.1 - 0.00029 19.6 1.0 0.0018 17.1 1.2 2.0 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.21 CRK36903.1 - 0.00048 19.5 2.0 0.00099 18.5 2.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 CRK36903.1 - 0.0025 17.0 3.6 0.0025 17.0 3.6 2.4 3 0 0 3 3 3 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 CRK36903.1 - 0.02 14.1 0.1 0.045 13.0 0.2 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CRK36903.1 - 0.039 13.2 1.6 0.11 11.8 0.4 2.2 2 0 0 2 2 2 0 Thi4 family Lycopene_cycl PF05834.12 CRK36903.1 - 0.5 9.4 3.9 0.15 11.0 0.8 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein WSC PF01822.19 CRK36906.1 - 4.9e-21 74.7 8.9 1.8e-20 72.9 8.9 2.0 1 0 0 1 1 1 1 WSC domain Ge1_WD40 PF16529.5 CRK36908.1 - 4.5e-05 22.6 0.0 0.0052 15.8 0.0 2.7 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40 PF00400.32 CRK36908.1 - 0.00051 20.8 2.0 38 5.4 0.0 5.9 6 0 0 6 6 6 0 WD domain, G-beta repeat PD40 PF07676.12 CRK36908.1 - 0.0013 18.6 0.1 2.7 8.0 0.0 3.6 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.11 CRK36908.1 - 0.0038 16.0 0.0 0.006 15.4 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Pox_Ag35 PF03286.14 CRK36908.1 - 6.1 6.6 9.2 5 6.9 4.9 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein BUD22 PF09073.10 CRK36908.1 - 8.3 5.6 18.4 14 4.9 11.7 2.2 2 0 0 2 2 2 0 BUD22 Rad4 PF03835.15 CRK36910.1 - 1.2e-13 50.9 2.8 2.4e-13 50.0 2.8 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.19 CRK36910.1 - 7.1e-12 45.8 2.1 1.5e-11 44.8 2.1 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily Ank_2 PF12796.7 CRK36911.1 - 1.5e-42 144.0 13.2 4.1e-13 49.7 0.1 6.8 5 1 1 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CRK36911.1 - 3.8e-30 103.9 11.5 1.3e-08 35.2 0.0 7.8 5 2 2 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 CRK36911.1 - 5.8e-28 93.8 14.4 0.004 17.5 0.0 12.9 13 0 0 13 13 13 6 Ankyrin repeat Ank_5 PF13857.6 CRK36911.1 - 8.6e-24 83.3 12.9 0.00019 21.6 0.1 9.3 7 2 3 10 10 10 6 Ankyrin repeats (many copies) Ank PF00023.30 CRK36911.1 - 7.8e-19 67.2 28.1 0.0046 17.4 0.0 11.2 11 1 0 11 11 11 7 Ankyrin repeat Ribosomal_S5 PF00333.20 CRK36913.1 - 1.8e-27 95.1 1.0 4.1e-27 94.0 1.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 CRK36913.1 - 1.3e-23 82.2 0.1 2.5e-23 81.3 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Phage_tail_NK PF16532.5 CRK36913.1 - 0.12 12.0 0.1 0.19 11.3 0.1 1.3 1 0 0 1 1 1 0 Sf6-type phage tail needle knob or tip of some Caudovirales FoP_duplication PF13865.6 CRK36913.1 - 1.8 9.2 14.2 3.9 8.1 14.2 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Rhodanese PF00581.20 CRK36915.1 - 1.4e-17 64.1 0.0 9.2e-10 39.0 0.0 2.4 2 1 0 2 2 2 2 Rhodanese-like domain DAP_epimerase PF01678.19 CRK36915.1 - 0.083 13.1 0.0 2.1 8.6 0.0 2.3 2 0 0 2 2 2 0 Diaminopimelate epimerase FBPase PF00316.20 CRK36917.1 - 7.2e-25 87.6 0.0 3.8e-24 85.2 0.0 1.9 2 0 0 2 2 2 1 Fructose-1-6-bisphosphatase, N-terminal domain Syntaxin PF00804.25 CRK36919.1 - 2.1e-18 66.8 9.5 2.1e-18 66.8 9.5 1.6 1 1 1 2 2 2 1 Syntaxin SNARE PF05739.19 CRK36919.1 - 2.2e-11 43.6 1.2 7.1e-11 41.9 0.4 2.2 2 0 0 2 2 2 1 SNARE domain Mod_r PF07200.13 CRK36919.1 - 0.0036 17.4 7.5 0.14 12.2 3.3 2.3 2 0 0 2 2 2 2 Modifier of rudimentary (Mod(r)) protein TACC_C PF05010.14 CRK36919.1 - 0.005 16.7 4.8 0.63 9.8 0.0 2.2 2 0 0 2 2 2 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal LAP1C PF05609.12 CRK36919.1 - 0.0055 15.9 2.8 0.0076 15.4 2.8 1.2 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) DUF515 PF04415.12 CRK36919.1 - 0.019 13.4 1.9 0.02 13.3 0.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF515) DUF1676 PF07898.13 CRK36919.1 - 0.034 14.2 0.2 0.054 13.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) Arch_flagellin PF01917.16 CRK36919.1 - 0.043 14.0 0.1 0.11 12.7 0.1 1.7 1 0 0 1 1 1 0 Archaebacterial flagellin DUF5305 PF17231.2 CRK36919.1 - 0.085 12.2 0.1 0.16 11.4 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5305) MCPsignal PF00015.21 CRK36919.1 - 0.16 11.8 8.4 0.28 11.0 4.5 2.3 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Cytochrome_B PF00033.19 CRK36919.1 - 0.18 11.6 0.3 0.27 11.0 0.3 1.1 1 0 0 1 1 1 0 Cytochrome b/b6/petB 7tm_7 PF08395.12 CRK36919.1 - 0.71 9.0 0.0 0.71 9.0 0.0 2.4 2 1 0 2 2 2 0 7tm Chemosensory receptor DUF4709 PF15821.5 CRK36919.1 - 0.85 9.9 9.0 4.2 7.7 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4709) MCU PF04678.13 CRK36919.1 - 1.2 9.2 6.2 0.37 10.9 2.2 1.9 1 1 1 2 2 2 0 Mitochondrial calcium uniporter 4HB_MCP_1 PF12729.7 CRK36919.1 - 1.4 8.4 6.4 1.1 8.8 0.0 2.7 2 1 0 2 2 2 0 Four helix bundle sensory module for signal transduction DUF2203 PF09969.9 CRK36919.1 - 4.9 7.9 8.8 6.8 7.4 3.4 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF2951 PF11166.8 CRK36919.1 - 5.8 7.2 6.2 3.3 8.0 0.7 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2951) V-SNARE PF05008.15 CRK36919.1 - 9.9 6.6 13.5 0.29 11.5 2.6 2.9 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus CTC1_2 PF15491.6 CRK36922.1 - 0.019 14.3 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 CST, telomere maintenance, complex subunit CTC1 GNAT_acetyltr_2 PF13718.6 CRK36923.1 - 1.4e-99 332.2 0.0 2.6e-99 331.2 0.0 1.5 1 0 0 1 1 1 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 CRK36923.1 - 5.2e-93 311.1 0.2 9e-93 310.3 0.2 1.4 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 CRK36923.1 - 2.4e-65 219.7 0.0 1.1e-64 217.6 0.0 2.2 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 CRK36923.1 - 1.7e-32 111.2 0.0 4.8e-32 109.7 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) NAPRTase PF04095.16 CRK36923.1 - 1.9e-31 109.5 0.5 1.6e-29 103.2 0.5 2.4 1 1 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 CRK36923.1 - 1.6e-27 96.3 0.4 4.9e-27 94.8 0.4 1.8 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain AAA_30 PF13604.6 CRK36923.1 - 0.00012 21.8 0.1 0.011 15.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain GHMP_kinases_N PF00288.26 CRK36923.1 - 0.083 13.1 0.1 0.23 11.7 0.1 1.7 1 0 0 1 1 1 0 GHMP kinases N terminal domain PG_binding_1 PF01471.18 CRK36924.1 - 0.012 15.9 0.0 4 7.7 0.0 2.8 2 0 0 2 2 2 0 Putative peptidoglycan binding domain SlyX PF04102.12 CRK36924.1 - 1.3 9.7 3.6 5.8 7.6 0.1 3.0 3 0 0 3 3 3 0 SlyX WD40 PF00400.32 CRK36925.1 - 2.6e-12 47.0 14.3 0.00012 22.8 0.0 9.5 12 0 0 12 12 12 4 WD domain, G-beta repeat Pam16 PF03656.13 CRK36929.1 - 8.7e-19 67.8 0.0 1e-18 67.6 0.0 1.0 1 0 0 1 1 1 1 Pam16 adh_short PF00106.25 CRK36931.1 - 3.9e-08 33.0 0.0 4.2e-08 32.9 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK36931.1 - 0.0002 21.0 0.0 0.00021 20.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Hexokinase_2 PF03727.16 CRK36932.1 - 4.2e-28 98.4 0.0 6.6e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 Hexokinase E1-E2_ATPase PF00122.20 CRK36932.1 - 1.6e-11 44.0 0.0 2.7e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 E1-E2 ATPase Lgl_C PF08596.10 CRK36933.1 - 1.4e-08 33.9 0.0 1.7e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal ANAPC4_WD40 PF12894.7 CRK36933.1 - 0.002 18.4 0.0 0.23 11.8 0.0 2.1 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Methyltransf_32 PF13679.6 CRK36934.1 - 7.3e-08 32.6 0.0 7.6e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain FmrO PF07091.11 CRK36934.1 - 0.069 12.7 0.1 0.073 12.6 0.1 1.1 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) tRNA-synt_1 PF00133.22 CRK36935.1 - 1.3e-24 86.4 0.1 1.4e-24 86.3 0.1 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 CRK36935.1 - 3.9e-08 33.0 0.0 4.5e-08 32.8 0.0 1.0 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 GRAB PF10375.9 CRK36936.1 - 2.7e-10 39.7 0.4 1.3e-09 37.5 0.1 2.3 2 0 0 2 2 2 1 GRIP-related Arf-binding domain Prominin PF05478.11 CRK36936.1 - 0.00072 17.7 2.4 0.0008 17.5 2.4 1.2 1 0 0 1 1 1 1 Prominin tRNA_synt_1c_R1 PF04558.15 CRK36936.1 - 0.017 15.1 2.6 0.017 15.1 2.6 1.9 1 1 1 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 DUF4407 PF14362.6 CRK36936.1 - 0.022 14.1 13.4 0.027 13.9 13.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Seryl_tRNA_N PF02403.22 CRK36936.1 - 0.026 14.7 12.7 0.026 14.7 12.7 2.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain NPV_P10 PF05531.12 CRK36936.1 - 0.028 14.9 6.8 0.028 14.9 2.2 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein ATG16 PF08614.11 CRK36936.1 - 0.034 14.4 24.0 0.11 12.7 24.0 1.7 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Spc7 PF08317.11 CRK36936.1 - 0.037 12.9 17.4 0.044 12.7 17.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein TMF_DNA_bd PF12329.8 CRK36936.1 - 0.038 14.0 24.1 0.038 14.0 14.0 2.5 3 0 0 3 3 2 0 TATA element modulatory factor 1 DNA binding Fib_alpha PF08702.10 CRK36936.1 - 0.086 13.0 9.3 0.15 12.2 6.2 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family 7TMR-HDED PF07697.11 CRK36936.1 - 0.11 12.6 9.9 0.12 12.5 9.9 1.2 1 0 0 1 1 1 0 7TM-HD extracellular Ribosomal_L35p PF01632.19 CRK36936.1 - 0.12 12.9 0.2 0.45 11.1 0.2 2.1 1 0 0 1 1 1 0 Ribosomal protein L35 Dpy-30 PF05186.13 CRK36936.1 - 0.12 12.1 0.0 0.27 10.9 0.0 1.6 1 1 0 1 1 1 0 Dpy-30 motif Laminin_II PF06009.12 CRK36936.1 - 0.14 12.2 13.0 0.19 11.8 8.3 2.1 1 1 1 2 2 2 0 Laminin Domain II Exonuc_VII_L PF02601.15 CRK36936.1 - 0.24 10.9 11.4 0.29 10.7 11.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1664 PF07889.12 CRK36936.1 - 0.27 11.3 7.1 0.26 11.3 5.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Scaffolding_pro PF11418.8 CRK36936.1 - 0.29 11.7 4.8 0.14 12.7 1.5 2.1 2 1 0 2 2 1 0 Phi29 scaffolding protein DUF4200 PF13863.6 CRK36936.1 - 0.55 10.6 21.4 0.22 11.9 12.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Syntaxin-6_N PF09177.11 CRK36936.1 - 0.62 10.7 11.3 1.4 9.5 10.3 2.2 1 1 0 1 1 1 0 Syntaxin 6, N-terminal KxDL PF10241.9 CRK36936.1 - 0.62 10.4 9.3 1.3 9.4 1.3 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein T3SSipB PF16535.5 CRK36936.1 - 0.7 10.4 17.1 1.4 9.4 17.1 1.6 1 1 0 1 1 1 0 Type III cell invasion protein SipB DUF3584 PF12128.8 CRK36936.1 - 0.72 7.3 19.3 0.83 7.1 19.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Macoilin PF09726.9 CRK36936.1 - 0.84 8.1 19.8 0.96 7.9 19.8 1.0 1 0 0 1 1 1 0 Macoilin family Csm1_N PF18504.1 CRK36936.1 - 1 9.8 21.0 4.7 7.6 5.6 4.0 2 1 2 4 4 4 0 Csm1 N-terminal domain CENP-F_leu_zip PF10473.9 CRK36936.1 - 1.3 9.1 21.9 1.6 8.7 21.7 1.3 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4735 PF15882.5 CRK36936.1 - 1.3 8.4 4.3 1.7 8.0 3.7 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4735) TMPIT PF07851.13 CRK36936.1 - 1.6 7.9 11.2 0.91 8.7 9.4 1.4 1 1 0 1 1 1 0 TMPIT-like protein P4Ha_N PF08336.11 CRK36936.1 - 1.6 8.7 15.7 0.74 9.8 2.9 3.0 2 1 1 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Cauli_AT PF03233.13 CRK36936.1 - 1.7 8.6 6.5 0.65 9.9 2.5 2.1 1 1 1 2 2 2 0 Aphid transmission protein DUF948 PF06103.11 CRK36936.1 - 1.9 8.8 7.6 1.5 9.1 0.8 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4472 PF14739.6 CRK36936.1 - 2.1 9.1 18.9 0.51 11.1 11.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) XhlA PF10779.9 CRK36936.1 - 2.4 8.4 12.2 2.8 8.2 2.0 2.4 2 0 0 2 2 2 0 Haemolysin XhlA OEP PF02321.18 CRK36936.1 - 2.6 7.8 18.4 4 7.2 18.4 1.2 1 0 0 1 1 1 0 Outer membrane efflux protein TPR_MLP1_2 PF07926.12 CRK36936.1 - 2.7 8.1 23.8 5.8 7.0 23.6 1.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Occludin_ELL PF07303.13 CRK36936.1 - 2.7 8.8 9.9 0.61 10.8 4.9 2.2 1 1 2 3 3 2 0 Occludin homology domain Atg14 PF10186.9 CRK36936.1 - 3 6.8 10.5 4 6.4 10.5 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FUSC PF04632.12 CRK36936.1 - 3.1 6.2 7.6 3.3 6.1 7.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family MCU PF04678.13 CRK36936.1 - 4.9 7.2 9.7 9.8 6.2 9.5 1.6 1 1 0 1 1 1 0 Mitochondrial calcium uniporter OmpH PF03938.14 CRK36936.1 - 6 7.2 21.4 22 5.4 21.4 1.8 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) MTES_1575 PF18741.1 CRK36937.1 - 0.15 12.3 0.1 0.21 11.8 0.1 1.3 1 0 0 1 1 1 0 REase_MTES_1575 DUF1593 PF07632.11 CRK36938.1 - 2.9e-14 53.1 0.0 3.1e-14 53.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) PEX11 PF05648.14 CRK36944.1 - 3.4e-19 69.2 0.0 3.6e-19 69.1 0.0 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) MFS_1 PF07690.16 CRK36947.1 - 0.0086 15.0 2.3 0.0089 15.0 2.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily E1-E2_ATPase PF00122.20 CRK36949.1 - 3.8e-19 68.9 0.4 3.9e-19 68.9 0.4 1.0 1 0 0 1 1 1 1 E1-E2 ATPase TrkH PF02386.16 CRK36951.1 - 2.9e-68 230.6 0.8 3.2e-68 230.4 0.8 1.0 1 0 0 1 1 1 1 Cation transport protein Adaptin_N PF01602.20 CRK36952.1 - 1.7e-24 86.3 0.3 1.7e-24 86.3 0.3 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT PF02985.22 CRK36952.1 - 0.00038 20.5 0.0 0.0015 18.6 0.0 1.9 2 0 0 2 2 2 1 HEAT repeat Cnd1 PF12717.7 CRK36952.1 - 0.00041 20.4 0.5 0.081 13.0 0.1 2.0 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.7 CRK36952.1 - 0.00093 19.5 0.1 0.0033 17.7 0.0 1.9 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion HEAT_2 PF13646.6 CRK36952.1 - 0.025 15.0 0.0 0.027 14.8 0.0 1.3 1 1 0 1 1 1 0 HEAT repeats Gelsolin PF00626.22 CRK36954.1 - 0.00014 21.7 0.0 0.0002 21.2 0.0 1.4 1 0 0 1 1 1 1 Gelsolin repeat DUF4246 PF14033.6 CRK36955.1 - 5e-39 134.7 0.0 5.5e-39 134.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.6 CRK36955.1 - 0.004 17.6 0.0 0.0048 17.3 0.0 1.3 1 1 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase 2OG-FeII_Oxy_3 PF13640.6 CRK36955.1 - 0.15 13.0 0.0 0.16 12.9 0.0 1.2 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily UvrD_C PF13361.6 CRK36956.1 - 4.8e-06 26.2 0.0 5e-06 26.1 0.0 1.0 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Zn_clus PF00172.18 CRK36958.1 - 1.2e-08 35.0 9.1 1.6e-08 34.5 9.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Toluene_X PF03349.16 CRK36958.1 - 0.22 10.0 0.0 0.25 9.9 0.0 1.0 1 0 0 1 1 1 0 Outer membrane protein transport protein (OMPP1/FadL/TodX) Troponin-I_N PF11636.8 CRK36959.1 - 2.4 8.2 10.7 0.14 12.2 3.6 1.9 1 1 1 2 2 2 0 Troponin I residues 1-32 Coa1 PF08695.10 CRK36960.1 - 2.5e-16 59.4 0.0 3e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 p450 PF00067.22 CRK36963.1 - 1.3e-20 73.7 0.0 1.4e-20 73.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 EF-hand_1 PF00036.32 CRK36967.1 - 8.8e-15 53.1 13.2 7.8e-06 25.1 0.6 3.1 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 CRK36967.1 - 9.1e-13 48.5 4.2 1.3e-10 41.6 0.8 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CRK36967.1 - 1.8e-10 39.9 7.6 2.4e-05 23.9 0.3 3.2 3 1 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 CRK36967.1 - 8.8e-09 34.5 9.4 0.0035 16.8 0.1 3.3 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 CRK36967.1 - 8.1e-06 25.6 9.4 0.0038 17.1 1.2 3.2 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 CRK36967.1 - 0.0029 17.5 7.4 0.55 10.2 0.5 3.0 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 CRK36967.1 - 0.03 14.5 3.2 0.043 14.0 1.5 2.1 2 1 1 3 3 3 0 Dockerin type I domain SPARC_Ca_bdg PF10591.9 CRK36967.1 - 0.042 14.2 0.1 0.08 13.3 0.1 1.6 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region HMG_CoA_synt_N PF01154.17 CRK36973.1 - 5.3e-70 234.8 0.3 6.5e-70 234.5 0.3 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 CRK36973.1 - 1.5e-25 90.4 0.3 2e-25 90.0 0.3 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal DUF5040 PF16443.5 CRK36973.1 - 0.13 11.7 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5040) VIT1 PF01988.19 CRK36975.1 - 2.2e-15 57.1 0.0 3.4e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 VIT family Fungal_trans_2 PF11951.8 CRK36980.1 - 1.4e-05 24.1 0.0 1.5e-05 24.0 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain SPEG_u2 PF16650.5 CRK36980.1 - 0.1 12.8 0.1 0.14 12.3 0.1 1.3 1 0 0 1 1 1 0 Unstructured region on SPEG complex protein Arf PF00025.21 CRK36985.1 - 1.5e-08 34.3 0.0 1.7e-08 34.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CRK36985.1 - 0.00016 21.2 0.0 0.00019 21.0 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Ras PF00071.22 CRK36985.1 - 0.11 12.1 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Ras family Aldedh PF00171.22 CRK36987.1 - 5.8e-17 61.3 0.1 6.7e-17 61.1 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SNX17_FERM_C PF18116.1 CRK36993.1 - 0.044 13.9 0.0 0.058 13.5 0.0 1.1 1 0 0 1 1 1 0 Sorting Nexin 17 FERM C-terminal domain zf-UBP_var PF17807.1 CRK36999.1 - 1.5e-24 85.5 0.5 2.1e-22 78.7 0.0 2.4 2 0 0 2 2 2 2 Variant UBP zinc finger zf-UBP PF02148.19 CRK36999.1 - 6.5e-24 84.1 11.4 4e-21 75.1 1.3 2.8 3 0 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein zf-UBR PF02207.20 CRK36999.1 - 2.6 8.3 11.8 11 6.3 0.7 4.0 4 0 0 4 4 4 0 Putative zinc finger in N-recognin (UBR box) DEAD PF00270.29 CRK37000.1 - 9.3e-51 172.1 0.0 1.5e-50 171.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase BSP_II PF05432.11 CRK37000.1 - 0.63 9.7 21.5 0.94 9.1 21.5 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Dicty_REP PF05086.12 CRK37000.1 - 5.9 4.7 8.2 8.3 4.3 8.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Na_H_Exchanger PF00999.21 CRK37001.1 - 4.9e-38 130.9 18.0 6.7e-38 130.5 18.0 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.6 CRK37001.1 - 1.1 9.5 6.0 0.76 9.9 0.6 3.2 3 0 0 3 3 3 0 YrhC-like protein Popeye PF04831.13 CRK37001.1 - 6.9 6.8 5.6 56 3.9 0.0 2.5 2 0 0 2 2 2 0 Popeye protein conserved region NifU_N PF01592.16 CRK37003.1 - 2.9e-50 169.7 0.0 3.8e-50 169.3 0.0 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain UCH PF00443.29 CRK37004.1 - 7.7e-37 127.2 0.0 1.4e-36 126.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 CRK37004.1 - 2.7e-23 81.5 0.5 8.2e-22 76.7 0.0 2.6 2 0 0 2 2 2 1 Variant UBP zinc finger zf-UBP PF02148.19 CRK37004.1 - 1.4e-22 79.7 11.5 3.2e-20 72.2 1.3 3.2 3 0 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.31 CRK37004.1 - 1.2e-19 69.8 0.1 1.2e-09 37.9 0.1 2.6 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.6 CRK37004.1 - 2.5e-17 63.5 0.1 3.4e-15 56.5 0.0 3.5 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Ribosomal_L33 PF00471.20 CRK37004.1 - 0.058 13.8 2.3 4.1 7.9 0.8 2.7 2 0 0 2 2 2 0 Ribosomal protein L33 HORMA PF02301.18 CRK37005.1 - 1e-32 113.5 0.0 1.2e-32 113.2 0.0 1.0 1 0 0 1 1 1 1 HORMA domain ATG101 PF07855.12 CRK37005.1 - 0.00036 20.5 0.6 0.0017 18.4 0.6 1.9 1 1 0 1 1 1 1 Autophagy-related protein 101 zf-RING_2 PF13639.6 CRK37006.1 - 0.00061 20.1 1.2 0.00061 20.1 1.2 3.5 3 0 0 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.6 CRK37006.1 - 0.0031 17.5 0.3 0.0031 17.5 0.3 2.5 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 CRK37006.1 - 0.014 15.3 0.4 0.014 15.3 0.4 2.8 3 0 0 3 3 3 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 CRK37006.1 - 0.016 15.3 0.4 0.016 15.3 0.4 3.0 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 CRK37006.1 - 0.031 14.1 0.2 0.031 14.1 0.2 3.2 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CRK37006.1 - 0.033 14.0 0.3 0.033 14.0 0.3 2.9 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CRK37006.1 - 0.048 13.7 1.0 0.17 11.9 1.0 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 CRK37006.1 - 0.084 13.2 0.5 0.084 13.2 0.5 2.5 2 0 0 2 2 2 0 RING-H2 zinc finger domain p450 PF00067.22 CRK37007.1 - 5.8e-65 219.8 0.0 5.8e-64 216.5 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 BTP PF05232.12 CRK37007.1 - 0.038 14.1 0.9 0.079 13.0 0.9 1.5 1 0 0 1 1 1 0 Chlorhexidine efflux transporter Ferric_reduct PF01794.19 CRK37008.1 - 5.6e-24 84.7 7.9 5.6e-24 84.7 7.9 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 CRK37008.1 - 5.4e-14 52.6 0.0 8.3e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 CRK37008.1 - 8.8e-09 35.4 0.0 1.7e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 CRK37008.1 - 0.00031 21.4 0.0 0.00077 20.1 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Glycophorin_A PF01102.18 CRK37008.1 - 0.14 12.4 0.4 1.5 9.0 0.0 2.5 2 0 0 2 2 2 0 Glycophorin A DUF1418 PF07214.12 CRK37008.1 - 0.17 11.8 0.0 0.17 11.8 0.0 2.8 3 1 2 5 5 5 0 Protein of unknown function (DUF1418) Ctr PF04145.15 CRK37009.1 - 2.4e-37 128.8 0.0 2.9e-37 128.5 0.0 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Glyco_hydro_114 PF03537.13 CRK37010.1 - 3.9e-81 271.8 0.0 4.9e-81 271.4 0.0 1.1 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 Fungal_trans PF04082.18 CRK37011.1 - 6.8e-37 126.9 8.0 1.2e-24 86.8 1.6 2.7 2 1 0 2 2 2 2 Fungal specific transcription factor domain Glyco_transf_90 PF05686.12 CRK37011.1 - 0.026 13.5 0.0 6.7 5.5 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 90 Flu_NS1 PF00600.19 CRK37011.1 - 0.028 14.0 0.0 8.8 5.8 0.0 2.2 2 0 0 2 2 2 0 Influenza non-structural protein (NS1) DUF553 PF04473.12 CRK37011.1 - 0.1 12.1 0.1 16 5.0 0.0 2.4 2 0 0 2 2 2 0 Transglutaminase-like domain Mito_fiss_reg PF05308.11 CRK37011.1 - 4.9 7.2 6.0 25 4.8 0.9 2.6 2 0 0 2 2 2 0 Mitochondrial fission regulator CAP_N PF01213.19 CRK37011.1 - 9.4 5.6 14.2 12 5.3 1.6 2.3 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Ctr PF04145.15 CRK37012.1 - 6.6e-16 59.3 2.1 1e-15 58.7 2.1 1.3 1 0 0 1 1 1 1 Ctr copper transporter family MR_MLE_N PF02746.16 CRK37012.1 - 2.1e-07 31.1 0.0 3.5e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Glyco_hydro_114 PF03537.13 CRK37013.1 - 3e-43 147.8 0.1 7.5e-33 113.8 0.0 2.1 1 1 1 2 2 2 2 Glycoside-hydrolase family GH114 ABC2_membrane_2 PF12679.7 CRK37014.1 - 0.9 8.8 6.3 1.2 8.4 6.3 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein MR_MLE_N PF02746.16 CRK37015.1 - 1.6e-08 34.8 0.0 1.9e-06 28.1 0.0 2.3 2 0 0 2 2 2 2 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain adh_short PF00106.25 CRK37016.1 - 1.6e-31 109.3 0.1 2.2e-31 108.8 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK37016.1 - 1.4e-29 103.3 0.1 2.8e-29 102.3 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK37016.1 - 3.3e-09 36.9 0.4 5.9e-09 36.1 0.4 1.4 1 0 0 1 1 1 1 KR domain MR_MLE_C PF13378.6 CRK37016.1 - 1.8e-08 34.2 0.0 4.3e-08 33.0 0.0 1.6 2 0 0 2 2 2 1 Enolase C-terminal domain-like adh_short_C2 PF13561.6 CRK37017.1 - 1.7e-54 184.9 0.0 2e-54 184.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRK37017.1 - 3.9e-40 137.4 0.0 4.7e-40 137.1 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CRK37017.1 - 2.6e-09 37.2 0.2 3.5e-09 36.8 0.2 1.1 1 0 0 1 1 1 1 KR domain Hydrolase_6 PF13344.6 CRK37020.1 - 7.7e-23 80.5 0.0 1.7e-22 79.4 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CRK37020.1 - 9.8e-15 54.4 0.0 3.2e-14 52.7 0.0 1.9 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 CRK37020.1 - 0.0036 17.6 0.0 5.9 7.1 0.0 2.9 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Mitochondr_Som1 PF11093.8 CRK37022.1 - 1.7e-26 92.0 0.0 3.4e-25 87.9 0.0 2.1 2 0 0 2 2 2 1 Mitochondrial export protein Som1 COX6C PF02937.15 CRK37023.1 - 0.0088 16.2 0.0 0.011 15.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIc Ribosomal_L22 PF00237.19 CRK37024.1 - 2.6e-22 79.0 0.0 4.6e-22 78.2 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein L22p/L17e Pantoate_ligase PF02569.15 CRK37024.1 - 0.15 11.3 2.2 0.31 10.2 2.2 1.5 1 1 0 1 1 1 0 Pantoate-beta-alanine ligase CFEM PF05730.11 CRK37025.1 - 2.4e-13 49.9 10.5 4.3e-13 49.2 10.5 1.4 1 0 0 1 1 1 1 CFEM domain SKG6 PF08693.10 CRK37025.1 - 1.5e-05 24.3 1.7 3.7e-05 23.0 1.7 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain SOG2 PF10428.9 CRK37025.1 - 0.47 9.6 15.9 0.54 9.4 15.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein SPX PF03105.19 CRK37025.1 - 1.4 8.8 8.9 1.7 8.5 8.9 1.3 1 0 0 1 1 1 0 SPX domain Ndc1_Nup PF09531.10 CRK37025.1 - 1.6 7.4 9.6 2.1 6.9 9.6 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TFIIA PF03153.13 CRK37025.1 - 2.1 8.3 9.2 2.6 8.0 9.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hamartin PF04388.12 CRK37025.1 - 10 4.7 18.3 13 4.3 18.3 1.1 1 0 0 1 1 1 0 Hamartin protein RRM_1 PF00076.22 CRK37026.1 - 5e-46 154.4 0.0 3.2e-16 58.9 0.0 4.7 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CRK37026.1 - 7.3e-33 112.3 0.0 1.7e-24 85.5 0.0 3.4 3 0 0 3 3 3 3 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 CRK37026.1 - 1.9e-06 27.7 0.0 0.017 15.1 0.0 3.5 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 CRK37026.1 - 1e-05 25.1 0.0 0.00093 18.8 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.13 CRK37026.1 - 0.00072 19.5 0.0 0.76 9.8 0.0 3.5 2 1 1 3 3 3 2 Nup53/35/40-type RNA recognition motif RL PF17797.1 CRK37026.1 - 0.021 14.7 0.0 0.077 13.0 0.0 2.0 1 0 0 1 1 1 0 RL domain BRAP2 PF07576.12 CRK37026.1 - 0.067 13.4 0.0 0.28 11.4 0.0 2.0 3 0 0 3 3 3 0 BRCA1-associated protein 2 TPR_14 PF13428.6 CRK37026.1 - 3.5 8.7 0.0 3.5 8.7 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat HA2 PF04408.23 CRK37027.1 - 4e-15 56.0 1.0 1e-14 54.7 0.0 2.3 2 0 0 2 2 2 1 Helicase associated domain (HA2) DEAD PF00270.29 CRK37027.1 - 3.8e-10 39.8 0.0 8.3e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CRK37027.1 - 5.3e-07 30.0 0.5 2e-06 28.1 0.1 2.2 2 0 0 2 2 2 1 AAA domain OB_NTP_bind PF07717.16 CRK37027.1 - 7.7e-07 29.4 0.0 1.8e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CRK37027.1 - 0.005 17.2 0.0 0.011 16.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ABC_tran PF00005.27 CRK37027.1 - 0.015 15.8 0.0 0.05 14.1 0.0 1.9 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 CRK37027.1 - 0.046 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 CRK37027.1 - 0.058 13.9 2.9 0.33 11.4 0.0 2.9 3 0 0 3 3 3 0 AAA domain ATPase PF06745.13 CRK37027.1 - 0.11 11.9 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 KaiC RsgA_GTPase PF03193.16 CRK37027.1 - 0.15 12.0 0.0 0.74 9.7 0.0 2.2 3 0 0 3 3 3 0 RsgA GTPase DUF1421 PF07223.11 CRK37027.1 - 0.18 11.7 0.2 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 UBA-like domain (DUF1421) Gcn1_N PF12074.8 CRK37028.1 - 1.4e-126 422.7 4.6 1.4e-126 422.7 4.6 3.3 3 0 0 3 3 3 1 Generalcontrol nonderepressible 1 (Gcn1) N-terminal HEAT PF02985.22 CRK37028.1 - 5.1e-29 97.8 45.4 0.0015 18.6 0.0 22.3 26 0 0 26 26 22 7 HEAT repeat HEAT_EZ PF13513.6 CRK37028.1 - 2.6e-28 98.0 48.9 2.6e-06 27.8 0.0 19.6 14 4 8 22 22 21 6 HEAT-like repeat HEAT_2 PF13646.6 CRK37028.1 - 3.1e-22 78.8 53.7 1.4e-05 25.4 1.3 15.5 12 3 4 17 17 16 7 HEAT repeats Cnd1 PF12717.7 CRK37028.1 - 4.9e-15 55.9 3.1 0.071 13.2 0.2 10.4 6 2 5 12 12 11 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 CRK37028.1 - 7.2e-15 55.4 0.0 0.41 11.3 0.0 9.5 8 2 2 10 10 9 3 Vacuolar 14 Fab1-binding region ParcG PF10274.9 CRK37028.1 - 1.6e-12 48.0 4.6 0.00024 21.3 0.1 6.8 7 1 0 7 7 6 2 Parkin co-regulated protein CLASP_N PF12348.8 CRK37028.1 - 4.3e-10 39.6 0.0 0.12 12.0 0.0 6.3 5 2 1 6 6 5 2 CLASP N terminal MMS19_C PF12460.8 CRK37028.1 - 2e-08 33.8 12.0 0.018 14.1 0.2 6.0 3 3 3 6 6 6 2 RNAPII transcription regulator C-terminal UME PF08064.13 CRK37028.1 - 4.3e-08 33.0 3.4 0.76 9.7 0.0 7.5 8 0 0 8 8 7 1 UME (NUC010) domain Ecm29 PF13001.7 CRK37028.1 - 6.8e-05 21.7 0.2 2.9 6.4 0.0 4.4 3 2 0 3 3 3 2 Proteasome stabiliser DUF3385 PF11865.8 CRK37028.1 - 0.00023 21.1 0.5 4.1 7.3 0.0 6.1 6 2 0 6 6 6 1 Domain of unknown function (DUF3385) DUF937 PF06078.11 CRK37028.1 - 0.00027 21.5 9.8 5.5 7.6 0.0 7.5 6 3 1 7 7 7 1 Bacterial protein of unknown function (DUF937) TIP120 PF08623.10 CRK37028.1 - 0.0013 18.5 0.1 0.13 12.0 0.0 4.3 4 1 1 5 5 4 1 TATA-binding protein interacting (TIP20) TFCD_C PF12612.8 CRK37028.1 - 0.0014 18.5 0.5 0.015 15.2 0.0 3.1 2 1 1 3 3 3 1 Tubulin folding cofactor D C terminal IFRD PF05004.13 CRK37028.1 - 0.002 17.3 13.1 0.0041 16.3 2.5 5.0 5 1 0 5 5 5 1 Interferon-related developmental regulator (IFRD) Tti2 PF10521.9 CRK37028.1 - 0.0041 16.7 6.8 4.1 6.8 0.0 6.9 6 2 1 7 7 7 1 Tti2 family Adaptin_N PF01602.20 CRK37028.1 - 0.021 13.4 14.7 0.016 13.8 3.0 5.9 7 2 0 8 8 8 0 Adaptin N terminal region Cohesin_HEAT PF12765.7 CRK37028.1 - 0.13 12.6 3.9 4 7.8 0.1 4.8 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion DUF4276 PF14103.6 CRK37028.1 - 0.15 12.2 0.0 0.58 10.3 0.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4276) FANCI_S2 PF14676.6 CRK37028.1 - 0.15 12.3 0.3 2.5 8.4 0.1 3.1 3 0 0 3 3 3 0 FANCI solenoid 2 Ipi1_N PF12333.8 CRK37028.1 - 0.16 12.6 5.2 0.43 11.2 0.0 4.4 5 0 0 5 5 3 0 Rix1 complex component involved in 60S ribosome maturation U3snoRNP10 PF12397.8 CRK37028.1 - 4.8 7.6 13.6 26 5.2 0.0 7.0 6 1 0 6 6 5 0 U3 small nucleolar RNA-associated protein 10 Ribosomal_L19e PF01280.20 CRK37029.1 - 2.9e-33 114.9 7.1 2.9e-33 114.9 7.1 1.8 1 1 1 2 2 2 1 Ribosomal protein L19e SHMT PF00464.19 CRK37030.1 - 2.7e-195 648.6 0.0 3.4e-195 648.3 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 CRK37030.1 - 0.021 14.1 0.0 0.034 13.4 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 CRK37030.1 - 0.065 12.5 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family 2OG-FeII_Oxy_2 PF13532.6 CRK37031.1 - 8e-29 101.2 0.0 1.2e-28 100.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Isochorismatase PF00857.20 CRK37031.1 - 1.7e-20 73.9 0.0 5.1e-20 72.4 0.0 1.8 1 1 0 1 1 1 1 Isochorismatase family GST_C PF00043.25 CRK37031.1 - 0.00014 22.0 0.1 0.0003 20.9 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CRK37031.1 - 0.0022 18.0 0.0 0.0053 16.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CRK37031.1 - 0.02 15.0 0.0 0.045 13.9 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain WD40 PF00400.32 CRK37032.1 - 4e-43 144.5 26.4 1.2e-08 35.5 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK37032.1 - 1.6e-08 34.7 0.9 0.14 12.5 0.0 4.5 2 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CRK37032.1 - 0.00036 19.3 8.1 0.078 11.6 0.2 4.5 3 1 1 5 5 5 3 Nucleoporin Nup120/160 WD40_like PF17005.5 CRK37032.1 - 0.00038 19.9 0.0 0.56 9.5 0.0 3.0 2 1 0 3 3 3 2 WD40-like domain PD40 PF07676.12 CRK37032.1 - 0.017 15.0 0.4 23 5.1 0.0 4.4 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 CRK37032.1 - 0.044 12.7 0.1 8.4 5.2 0.0 3.4 2 2 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Bacillus_HBL PF05791.11 CRK37033.1 - 1.4 8.7 17.3 0.18 11.6 4.4 2.8 2 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Golgin_A5 PF09787.9 CRK37033.1 - 2.5 7.5 55.1 3.3 7.1 20.1 3.5 1 1 2 3 3 3 0 Golgin subfamily A member 5 Fib_alpha PF08702.10 CRK37033.1 - 5.3 7.2 27.6 0.46 10.7 6.3 2.8 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Leu_zip PF15294.6 CRK37033.1 - 5.4 6.5 49.1 2.5 7.5 16.9 2.5 1 1 1 2 2 2 0 Leucine zipper OST3_OST6 PF04756.13 CRK37034.1 - 2.2e-107 358.8 0.0 2.7e-107 358.5 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family VKOR PF07884.14 CRK37034.1 - 0.1 12.8 0.4 0.1 12.8 0.4 2.2 2 0 0 2 2 2 0 Vitamin K epoxide reductase family DUF3169 PF11368.8 CRK37034.1 - 1.1 8.8 4.2 1.5 8.3 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) Na_Ca_ex PF01699.24 CRK37034.1 - 2.7 8.0 9.2 1.5 8.8 2.8 2.2 1 1 1 2 2 2 0 Sodium/calcium exchanger protein Ribosomal_L18 PF17135.4 CRK37035.1 - 2.9e-92 307.2 3.2 3.2e-92 307.1 3.2 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 CRK37035.1 - 0.0098 16.6 0.2 0.0098 16.6 0.2 2.0 2 1 0 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Mito_carr PF00153.27 CRK37036.1 - 6.7e-72 237.5 2.5 1.9e-23 82.2 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CRK37036.1 - 2.6e-05 23.5 0.5 0.0016 17.7 0.1 3.1 3 1 0 3 3 3 1 Gammaproteobacterial serine protease PT-VENN PF04829.13 CRK37036.1 - 0.56 10.3 3.3 17 5.6 0.0 3.2 3 0 0 3 3 3 0 Pre-toxin domain with VENN motif RRM_1 PF00076.22 CRK37037.1 - 0.00039 20.2 0.0 0.0011 18.7 0.0 1.8 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAPS PF04499.15 CRK37037.1 - 2.5 6.8 3.4 2.6 6.7 3.4 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CH PF00307.31 CRK37038.1 - 9.1e-72 238.2 0.0 2.5e-18 66.2 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.6 CRK37038.1 - 8e-07 29.4 0.3 1.1e-05 25.8 0.1 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 CRK37038.1 - 8.7e-05 21.8 2.8 0.62 9.7 0.3 3.7 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 CRK37038.1 - 0.15 12.1 5.7 0.22 11.5 0.1 3.2 3 0 0 3 3 3 0 EF-hand domain CAMSAP_CH PF11971.8 CRK37038.1 - 0.17 11.7 0.0 17 5.3 0.0 3.0 3 0 0 3 3 3 0 CAMSAP CH domain ABC_membrane PF00664.23 CRK37040.1 - 1.3e-33 116.8 5.5 1.3e-33 116.8 5.5 1.7 2 0 0 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.27 CRK37040.1 - 3.2e-32 111.9 0.0 2.1e-31 109.2 0.0 2.2 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 CRK37040.1 - 1.2e-05 24.9 0.1 0.00027 20.4 0.0 2.6 1 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 CRK37040.1 - 0.033 14.1 0.0 0.079 12.9 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase SbcCD_C PF13558.6 CRK37040.1 - 0.082 13.2 0.2 1.5 9.1 0.2 2.7 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 CRK37040.1 - 0.1 12.3 0.1 0.35 10.6 0.1 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRAP PF02586.14 CRK37041.1 - 4.7e-82 274.8 0.2 8.6e-82 273.9 0.0 1.5 2 0 0 2 2 2 1 SOS response associated peptidase (SRAP) RNA_pol_Rpb1_5 PF04998.17 CRK37042.1 - 1.7e-121 404.7 0.0 7.8e-69 232.1 0.0 3.4 2 1 1 3 3 3 3 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 CRK37042.1 - 5.8e-82 275.5 0.0 1.2e-81 274.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 CRK37042.1 - 5e-72 241.5 0.0 9.3e-72 240.7 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_4 PF05000.17 CRK37042.1 - 8.2e-57 189.8 2.9 3e-27 94.7 0.2 2.8 2 0 0 2 2 2 2 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_3 PF04983.18 CRK37042.1 - 1.8e-53 180.7 0.0 1e-37 129.5 0.0 2.7 2 0 0 2 2 2 2 RNA polymerase Rpb1, domain 3 GPAT_N PF14829.6 CRK37042.1 - 0.052 13.5 0.0 1e+02 3.0 0.0 4.8 5 0 0 5 5 5 0 Glycerol-3-phosphate acyltransferase N-terminal TFIID_30kDa PF03540.13 CRK37042.1 - 0.069 13.1 0.1 27 4.8 0.0 2.9 2 0 0 2 2 2 0 Transcription initiation factor TFIID 23-30kDa subunit WhiA_N PF10298.9 CRK37042.1 - 0.1 12.7 0.7 28 4.8 0.1 2.9 2 0 0 2 2 2 0 WhiA N-terminal LAGLIDADG-like domain DUF835 PF05763.12 CRK37042.1 - 0.14 11.9 0.5 23 4.7 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF835) LytR_C PF13399.6 CRK37042.1 - 0.17 12.9 0.1 90 4.2 0.0 3.6 3 0 0 3 3 2 0 LytR cell envelope-related transcriptional attenuator Fibrillarin PF01269.17 CRK37042.1 - 0.51 9.4 2.7 11 5.0 0.2 2.3 2 0 0 2 2 2 0 Fibrillarin FlpD PF02662.16 CRK37042.1 - 0.53 10.3 2.4 29 4.7 0.1 2.9 3 0 0 3 3 3 0 Methyl-viologen-reducing hydrogenase, delta subunit DDHD PF02862.17 CRK37043.1 - 2.3e-63 214.3 0.0 2.3e-63 214.3 0.0 2.8 2 1 0 2 2 2 1 DDHD domain LIDHydrolase PF10230.9 CRK37043.1 - 0.11 12.0 0.1 0.28 10.7 0.0 1.6 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase AAR2 PF05282.11 CRK37043.1 - 0.14 11.6 0.8 0.22 10.9 0.0 1.7 2 0 0 2 2 2 0 AAR2 protein Ank_2 PF12796.7 CRK37044.1 - 0.033 14.8 0.0 0.062 13.9 0.0 1.4 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) zf-RING_2 PF13639.6 CRK37045.1 - 0.0085 16.4 2.8 0.0085 16.4 2.8 1.7 2 0 0 2 2 2 1 Ring finger domain Ank_2 PF12796.7 CRK37045.1 - 0.062 13.9 0.0 0.13 12.9 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Zn-ribbon_8 PF09723.10 CRK37045.1 - 2.4 8.3 4.5 30 4.9 1.7 2.4 2 0 0 2 2 2 0 Zinc ribbon domain DDHD PF02862.17 CRK37046.1 - 1.2e-63 215.2 0.0 1.2e-63 215.2 0.0 3.0 3 1 0 3 3 3 1 DDHD domain LIDHydrolase PF10230.9 CRK37046.1 - 0.11 12.1 0.1 0.26 10.8 0.0 1.6 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase AAR2 PF05282.11 CRK37046.1 - 0.14 11.5 1.4 0.27 10.6 0.0 2.0 2 0 0 2 2 2 0 AAR2 protein RNA_pol_Rpb1_1 PF04997.12 CRK37047.1 - 4.2e-83 279.3 0.0 5.7e-83 278.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 CRK37047.1 - 1.4e-72 243.3 0.0 2.3e-72 242.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 CRK37047.1 - 4.4e-11 43.0 0.0 7.7e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RRM_1 PF00076.22 CRK37047.1 - 1.3e-06 28.1 0.0 3.3e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L18 PF17135.4 CRK37048.1 - 1.6e-91 304.8 3.3 1.8e-91 304.6 3.3 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 CRK37048.1 - 0.0067 17.1 1.6 0.0079 16.9 0.1 2.0 2 1 0 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A OST3_OST6 PF04756.13 CRK37049.1 - 3.3e-108 361.5 0.0 4.1e-108 361.2 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family VKOR PF07884.14 CRK37049.1 - 0.1 12.8 0.4 0.1 12.8 0.4 2.2 2 0 0 2 2 2 0 Vitamin K epoxide reductase family DUF3169 PF11368.8 CRK37049.1 - 1 8.8 4.0 1.5 8.3 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) Na_Ca_ex PF01699.24 CRK37049.1 - 2.6 8.0 9.2 1.5 8.8 2.8 2.2 1 1 1 2 2 2 0 Sodium/calcium exchanger protein LPP PF04728.13 CRK37050.1 - 0.1 13.0 21.3 3.9 7.9 1.7 5.6 3 2 2 5 5 5 0 Lipoprotein leucine-zipper Bacillus_HBL PF05791.11 CRK37050.1 - 0.58 10.0 18.2 0.12 12.2 4.5 2.8 2 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Golgin_A5 PF09787.9 CRK37050.1 - 1.1 8.7 52.7 1.3 8.5 20.6 3.3 1 1 2 3 3 3 0 Golgin subfamily A member 5 bZIP_1 PF00170.21 CRK37050.1 - 1.3 9.2 37.4 1.1 9.4 8.0 5.7 2 2 2 5 5 5 0 bZIP transcription factor Csm1_N PF18504.1 CRK37050.1 - 1.9 8.9 40.7 2.7 8.4 0.8 7.0 2 2 5 7 7 7 0 Csm1 N-terminal domain Leu_zip PF15294.6 CRK37050.1 - 2.2 7.7 46.7 0.46 10.0 18.3 2.6 1 1 0 2 2 2 0 Leucine zipper Baculo_PEP_C PF04513.12 CRK37050.1 - 4.5 7.3 17.6 4.4 7.3 0.8 3.6 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.10 CRK37050.1 - 7.7 6.7 24.4 0.54 10.4 6.0 3.4 2 2 1 3 3 3 0 Fibrinogen alpha/beta chain family WD40 PF00400.32 CRK37051.1 - 4e-43 144.5 26.4 1.2e-08 35.5 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK37051.1 - 1.6e-08 34.7 0.9 0.14 12.5 0.0 4.5 2 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CRK37051.1 - 0.00036 19.3 8.1 0.078 11.6 0.2 4.5 3 1 1 5 5 5 3 Nucleoporin Nup120/160 WD40_like PF17005.5 CRK37051.1 - 0.00038 19.9 0.0 0.56 9.5 0.0 3.0 2 1 0 3 3 3 2 WD40-like domain PD40 PF07676.12 CRK37051.1 - 0.017 15.0 0.4 23 5.1 0.0 4.4 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 CRK37051.1 - 0.044 12.7 0.1 8.4 5.2 0.0 3.4 2 2 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein 2OG-FeII_Oxy_2 PF13532.6 CRK37052.1 - 8.2e-29 101.2 0.0 1.2e-28 100.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Isochorismatase PF00857.20 CRK37052.1 - 6.2e-21 75.3 0.0 1.9e-20 73.8 0.0 1.8 1 1 0 1 1 1 1 Isochorismatase family GST_C PF00043.25 CRK37052.1 - 0.00053 20.2 0.0 0.0011 19.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CRK37052.1 - 0.062 13.3 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CRK37052.1 - 0.068 13.4 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain SHMT PF00464.19 CRK37053.1 - 1.8e-175 583.4 0.2 1.1e-172 574.2 0.2 2.0 1 1 0 1 1 1 1 Serine hydroxymethyltransferase DegT_DnrJ_EryC1 PF01041.17 CRK37053.1 - 0.065 12.5 0.1 0.12 11.6 0.1 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Gcn1_N PF12074.8 CRK37054.1 - 5.8e-126 420.6 6.0 5.8e-126 420.6 6.0 3.5 3 0 0 3 3 3 1 Generalcontrol nonderepressible 1 (Gcn1) N-terminal HEAT PF02985.22 CRK37054.1 - 4.5e-32 107.3 43.2 0.0013 18.8 0.0 22.3 25 0 0 25 25 23 9 HEAT repeat HEAT_EZ PF13513.6 CRK37054.1 - 1.4e-27 95.7 58.3 2.3e-06 28.0 0.0 20.7 16 4 8 24 24 22 6 HEAT-like repeat HEAT_2 PF13646.6 CRK37054.1 - 6.1e-23 81.0 58.6 1.4e-05 25.4 1.5 16.1 12 4 6 19 19 18 9 HEAT repeats Cnd1 PF12717.7 CRK37054.1 - 3.7e-16 59.6 4.8 0.063 13.3 0.2 11.4 6 3 6 13 13 13 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 CRK37054.1 - 1.5e-15 57.5 0.0 0.36 11.4 0.0 9.8 8 2 2 10 10 10 3 Vacuolar 14 Fab1-binding region ParcG PF10274.9 CRK37054.1 - 3.4e-12 46.8 4.8 0.00043 20.5 0.1 7.0 7 1 0 7 7 7 2 Parkin co-regulated protein CLASP_N PF12348.8 CRK37054.1 - 5.5e-11 42.5 0.0 0.1 12.2 0.0 6.3 5 2 1 6 6 6 2 CLASP N terminal UME PF08064.13 CRK37054.1 - 5.7e-09 35.8 1.0 0.67 9.9 0.0 7.6 7 0 0 7 7 7 2 UME (NUC010) domain MMS19_C PF12460.8 CRK37054.1 - 1.3e-07 31.1 15.1 0.011 14.9 0.2 6.3 5 2 2 7 7 7 2 RNAPII transcription regulator C-terminal DUF937 PF06078.11 CRK37054.1 - 2.9e-05 24.7 6.9 4.8 7.8 0.0 7.2 5 2 1 6 6 6 1 Bacterial protein of unknown function (DUF937) DUF3385 PF11865.8 CRK37054.1 - 4.4e-05 23.4 0.7 1.5 8.7 0.0 6.4 6 3 1 7 7 7 1 Domain of unknown function (DUF3385) Ecm29 PF13001.7 CRK37054.1 - 8.2e-05 21.5 1.5 2.4 6.8 0.0 4.8 4 2 0 4 4 4 2 Proteasome stabiliser TIP120 PF08623.10 CRK37054.1 - 0.00068 19.4 0.2 0.13 12.0 0.0 4.6 4 1 1 5 5 5 1 TATA-binding protein interacting (TIP20) Adaptin_N PF01602.20 CRK37054.1 - 0.0016 17.1 17.5 0.014 14.0 2.2 7.2 8 3 1 10 10 10 1 Adaptin N terminal region TFCD_C PF12612.8 CRK37054.1 - 0.0017 18.3 1.9 0.013 15.4 0.0 3.5 3 1 0 3 3 3 1 Tubulin folding cofactor D C terminal Tti2 PF10521.9 CRK37054.1 - 0.0032 17.0 7.7 6.1 6.3 0.0 7.1 6 2 2 8 8 8 1 Tti2 family IFRD PF05004.13 CRK37054.1 - 0.0032 16.6 2.7 0.0032 16.6 2.7 5.2 7 1 1 8 8 8 1 Interferon-related developmental regulator (IFRD) Ipi1_N PF12333.8 CRK37054.1 - 0.07 13.7 5.5 0.41 11.3 0.0 4.5 6 0 0 6 6 3 0 Rix1 complex component involved in 60S ribosome maturation DUF4276 PF14103.6 CRK37054.1 - 0.11 12.8 0.0 0.39 10.9 0.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4276) FANCI_S2 PF14676.6 CRK37054.1 - 0.11 12.8 0.4 2.1 8.6 0.1 3.2 3 0 0 3 3 3 0 FANCI solenoid 2 HEAT_PBS PF03130.16 CRK37054.1 - 0.12 13.1 30.7 0.3 11.9 0.1 11.0 11 0 0 11 11 9 0 PBS lyase HEAT-like repeat U3snoRNP10 PF12397.8 CRK37054.1 - 3.8 7.9 14.3 23 5.4 0.0 7.2 6 1 0 6 6 5 0 U3 small nucleolar RNA-associated protein 10 HA2 PF04408.23 CRK37055.1 - 3.1e-15 56.4 0.7 9.9e-15 54.8 0.0 2.3 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CRK37055.1 - 2.1e-13 50.6 0.0 5.3e-13 49.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CRK37055.1 - 2.6e-10 40.4 0.0 5.4e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CRK37055.1 - 3.6e-07 30.5 0.1 1.2e-06 28.8 0.1 1.9 1 0 0 1 1 1 1 AAA domain OB_NTP_bind PF07717.16 CRK37055.1 - 7.9e-07 29.4 0.0 1.9e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold ABC_tran PF00005.27 CRK37055.1 - 0.013 16.0 0.0 0.05 14.1 0.0 2.0 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 CRK37055.1 - 0.045 13.5 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 CRK37055.1 - 0.062 13.8 1.9 0.49 10.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain ATPase PF06745.13 CRK37055.1 - 0.079 12.3 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 KaiC DUF1421 PF07223.11 CRK37055.1 - 0.14 12.0 0.2 1.3 8.9 0.0 2.3 2 0 0 2 2 2 0 UBA-like domain (DUF1421) RRM_1 PF00076.22 CRK37056.1 - 5.2e-46 154.3 0.0 1.5e-16 60.0 0.0 4.8 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CRK37056.1 - 3e-33 113.5 0.0 9.8e-25 86.2 0.0 3.4 3 0 0 3 3 3 3 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 CRK37056.1 - 5.4e-07 29.5 0.0 0.016 15.2 0.0 3.5 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 CRK37056.1 - 1.2e-05 25.0 0.0 0.00084 18.9 0.0 2.6 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 CRK37056.1 - 0.017 15.0 0.0 0.074 13.0 0.0 2.1 1 0 0 1 1 1 0 RL domain BRAP2 PF07576.12 CRK37056.1 - 0.059 13.6 0.0 0.27 11.5 0.0 2.1 3 0 0 3 3 3 0 BRCA1-associated protein 2 CFEM PF05730.11 CRK37057.1 - 3.1e-13 49.6 9.6 5.6e-13 48.8 9.6 1.4 1 0 0 1 1 1 1 CFEM domain SKG6 PF08693.10 CRK37057.1 - 1.3e-05 24.5 1.7 3.7e-05 23.0 1.7 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain RIFIN PF02009.16 CRK37057.1 - 0.17 11.8 0.7 36 4.1 0.0 2.0 1 1 1 2 2 2 0 Rifin CytochromB561_N PF09786.9 CRK37057.1 - 2.3 7.1 13.7 2.9 6.8 13.7 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Ndc1_Nup PF09531.10 CRK37057.1 - 2.4 6.8 10.1 3.1 6.4 10.1 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Ribosomal_L22 PF00237.19 CRK37058.1 - 8.5e-22 77.3 0.0 1.5e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e IFT57 PF10498.9 CRK37058.1 - 0.046 12.7 1.2 0.066 12.2 1.2 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 EcsC PF12787.7 CRK37058.1 - 0.051 13.2 0.2 0.078 12.6 0.2 1.3 1 0 0 1 1 1 0 EcsC protein family Hydrolase_6 PF13344.6 CRK37060.1 - 2e-22 79.2 0.0 4.6e-22 78.0 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CRK37060.1 - 7.4e-15 54.8 0.0 2.6e-14 53.0 0.0 2.0 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 CRK37060.1 - 0.0022 18.3 0.0 5.3 7.3 0.0 2.9 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase GCP_N_terminal PF17681.1 CRK37078.1 - 0.0051 16.5 0.1 0.0059 16.3 0.1 1.1 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal FPP PF05911.11 CRK37078.1 - 0.0051 15.1 1.8 0.0055 15.0 1.8 1.0 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil Laminin_II PF06009.12 CRK37078.1 - 0.008 16.2 1.2 0.011 15.8 1.2 1.2 1 0 0 1 1 1 1 Laminin Domain II SlyX PF04102.12 CRK37078.1 - 0.04 14.5 4.8 0.042 14.5 3.3 1.8 1 1 1 2 2 2 0 SlyX DHR10 PF18595.1 CRK37078.1 - 0.14 12.2 9.1 1.4 9.0 9.3 1.9 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain DUF3261 PF11659.8 CRK37080.1 - 0.18 11.7 0.0 0.22 11.4 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3261) DUF1744 PF08490.12 CRK37086.1 - 7.1e-25 87.4 0.7 1e-24 86.9 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) Aldose_epim PF01263.20 CRK37086.1 - 1.3e-13 50.9 0.1 1.8e-13 50.5 0.1 1.2 1 0 0 1 1 1 1 Aldose 1-epimerase Cpn60_TCP1 PF00118.24 CRK37086.1 - 6e-06 25.2 0.3 8e-06 24.8 0.3 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Dmrt1 PF12374.8 CRK37087.1 - 1.2 9.7 11.4 1.4 9.4 11.4 1.3 1 0 0 1 1 1 0 Double-sex mab3 related transcription factor 1 AA_permease_2 PF13520.6 CRK37088.1 - 3e-06 26.3 7.2 3e-06 26.3 7.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CRK37088.1 - 0.00027 19.7 6.5 0.0003 19.5 6.5 1.0 1 0 0 1 1 1 1 Amino acid permease DUF4267 PF14087.6 CRK37089.1 - 4.5e-11 42.8 0.7 4.7e-11 42.8 0.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) Fungal_trans PF04082.18 CRK37090.1 - 5.2e-20 71.6 0.2 5.6e-20 71.5 0.2 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain HTH_50 PF18024.1 CRK37090.1 - 0.036 13.7 0.3 0.05 13.2 0.3 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain DUF2686 PF10887.8 CRK37090.1 - 0.15 11.0 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2686) Maf PF02545.14 CRK37093.1 - 7e-14 52.0 0.0 7.6e-14 51.9 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein SYF2 PF08231.12 CRK37095.1 - 4.3e-28 98.7 3.2 4.8e-28 98.6 3.2 1.0 1 0 0 1 1 1 1 SYF2 splicing factor ARD PF03079.14 CRK37095.1 - 0.046 13.9 0.4 0.11 12.6 0.4 1.6 1 1 1 2 2 2 0 ARD/ARD' family Actin PF00022.19 CRK37097.1 - 6.6e-16 57.9 0.0 7.4e-16 57.8 0.0 1.1 1 0 0 1 1 1 1 Actin zf-CCHC PF00098.23 CRK37097.1 - 0.00076 19.5 1.2 0.00076 19.5 1.2 1.7 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_6 PF15288.6 CRK37097.1 - 0.01 15.7 1.6 0.02 14.7 0.5 2.1 2 0 0 2 2 2 0 Zinc knuckle HNH PF01844.23 CRK37097.1 - 0.04 14.1 1.7 0.07 13.3 0.1 2.2 3 0 0 3 3 3 0 HNH endonuclease Aldo_ket_red PF00248.21 CRK37098.1 - 2.5e-16 59.7 0.1 2.6e-16 59.7 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family YflT PF11181.8 CRK37098.1 - 0.11 13.0 0.0 0.63 10.6 0.0 1.9 1 1 1 2 2 2 0 Heat induced stress protein YflT COesterase PF00135.28 CRK37102.1 - 0.16 10.8 0.0 0.16 10.8 0.0 1.0 1 0 0 1 1 1 0 Carboxylesterase family OPT PF03169.15 CRK37103.1 - 2e-08 33.4 6.2 2.4e-08 33.1 6.2 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein CAP-ZIP_m PF15255.6 CRK37104.1 - 1.4 9.2 8.2 2.2 8.6 8.2 1.5 1 0 0 1 1 1 0 WASH complex subunit CAP-Z interacting, central region AMP-binding PF00501.28 CRK37107.1 - 3.4e-06 25.9 0.0 3.6e-06 25.9 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme FAR1 PF03101.15 CRK37112.1 - 0.0015 19.2 0.1 0.0018 19.0 0.1 1.1 1 0 0 1 1 1 1 FAR1 DNA-binding domain Glyco_hydro_2_N PF02837.18 CRK37113.1 - 0.005 16.8 0.0 0.0071 16.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain DUF4459 PF14673.6 CRK37117.1 - 0.055 13.4 0.0 0.074 13.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4459) Cullin PF00888.22 CRK37118.1 - 7.6e-33 114.0 4.2 8.7e-33 113.8 4.2 1.0 1 0 0 1 1 1 1 Cullin family Tap-RNA_bind PF09162.10 CRK37118.1 - 0.034 14.0 0.2 0.065 13.1 0.2 1.4 1 0 0 1 1 1 0 Tap, RNA-binding UDPGT PF00201.18 CRK37118.1 - 0.087 11.6 0.3 0.092 11.5 0.3 1.1 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase Rap1-DNA-bind PF09197.10 CRK37118.1 - 0.17 12.5 2.1 4.1 8.0 0.7 2.2 1 1 0 2 2 2 0 Rap1, DNA-binding Cupin_1 PF00190.22 CRK37119.1 - 1.2e-11 44.4 0.1 1.4e-11 44.3 0.1 1.1 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 CRK37119.1 - 0.03 14.0 0.0 0.044 13.5 0.0 1.3 1 0 0 1 1 1 0 Cupin domain UCH PF00443.29 CRK37122.1 - 5e-16 59.0 0.1 5.3e-16 58.9 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CRK37122.1 - 1.1e-07 31.8 0.0 1.2e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase APP_E2 PF12925.7 CRK37123.1 - 0.066 12.9 0.2 0.074 12.8 0.2 1.1 1 0 0 1 1 1 0 E2 domain of amyloid precursor protein HAGH_C PF16123.5 CRK37126.1 - 4e-22 78.5 0.3 6.3e-22 77.9 0.3 1.3 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 CRK37126.1 - 4.7e-14 52.8 6.8 4.6e-12 46.3 6.8 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Las1 PF04031.13 CRK37126.1 - 1.2e-11 44.9 0.0 2e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Las1-like Lactamase_B_2 PF12706.7 CRK37126.1 - 0.015 14.8 2.7 0.1 12.1 1.5 2.6 2 1 0 2 2 2 0 Beta-lactamase superfamily domain WSC PF01822.19 CRK37128.1 - 2.9e-57 190.8 56.0 9e-18 64.2 8.2 6.0 5 1 0 5 5 5 4 WSC domain peroxidase PF00141.23 CRK37128.1 - 1.5e-23 83.7 0.0 3.6e-23 82.5 0.0 1.6 1 0 0 1 1 1 1 Peroxidase RCR PF12273.8 CRK37129.1 - 5.2e-06 27.1 10.0 0.00069 20.3 0.3 2.7 2 0 0 2 2 2 2 Chitin synthesis regulation, resistance to Congo red MARVEL PF01284.23 CRK37129.1 - 0.00098 19.2 18.3 0.012 15.6 19.1 2.1 1 1 1 2 2 2 1 Membrane-associating domain HS1_rep PF02218.15 CRK37129.1 - 0.01 16.1 0.0 10 6.5 0.0 2.7 2 0 0 2 2 2 0 Repeat in HS1/Cortactin SUR7 PF06687.12 CRK37129.1 - 0.22 11.1 0.0 0.22 11.1 0.0 2.2 2 0 0 2 2 2 0 SUR7/PalI family FtsX PF02687.21 CRK37129.1 - 1.9 9.0 7.9 9.4 6.8 6.5 2.1 2 0 0 2 2 2 0 FtsX-like permease family DUF3402 PF11882.8 CRK37130.1 - 2e-194 647.0 0.0 3.4e-194 646.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.13 CRK37130.1 - 5e-89 298.3 0.4 7.1e-89 297.8 0.4 1.2 1 0 0 1 1 1 1 N1221-like protein NAD_kinase PF01513.21 CRK37131.1 - 2.6e-73 246.8 0.0 1.3e-72 244.5 0.0 1.9 1 1 0 1 1 1 1 ATP-NAD kinase Voldacs PF03517.13 CRK37131.1 - 0.055 13.6 0.1 0.12 12.5 0.1 1.6 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling DAGK_cat PF00781.24 CRK37131.1 - 0.057 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain zf-rbx1 PF12678.7 CRK37132.1 - 1.3e-09 38.2 1.0 2.4e-09 37.3 1.0 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CRK37132.1 - 1.2e-08 35.1 5.4 5.3e-08 33.1 2.1 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 CRK37132.1 - 1.7e-08 34.2 1.0 2.9e-08 33.4 1.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CRK37132.1 - 1.4e-07 31.2 7.0 7.6e-06 25.7 2.2 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CRK37132.1 - 4.2e-07 29.8 0.7 8e-07 28.9 0.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CRK37132.1 - 2.7e-06 27.3 1.5 8.5e-06 25.7 0.4 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CRK37132.1 - 5.8e-05 22.9 4.4 0.00011 22.0 1.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CRK37132.1 - 0.00014 21.6 0.6 0.00014 21.6 0.6 1.6 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 CRK37132.1 - 0.0016 18.1 8.0 0.0047 16.6 0.3 2.8 3 0 0 3 3 3 2 RING-like zinc finger DUF2921 PF11145.8 CRK37132.1 - 0.0044 15.0 2.3 0.01 13.7 0.2 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF2921) Zn_ribbon_17 PF17120.5 CRK37132.1 - 0.0057 16.3 0.5 0.013 15.1 0.5 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 CRK37132.1 - 0.015 15.3 0.6 0.043 13.9 0.6 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 CRK37132.1 - 3.1 8.1 4.9 17 5.7 4.9 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain HSBP1 PF06825.12 CRK37133.1 - 1.4e-15 56.9 0.2 1.5e-15 56.8 0.2 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Baculo_PEP_C PF04513.12 CRK37133.1 - 0.024 14.7 0.1 0.03 14.4 0.1 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Thioredoxin PF00085.20 CRK37134.1 - 1.3e-54 182.5 0.0 2.5e-29 101.3 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 CRK37134.1 - 6e-25 88.0 0.2 2e-24 86.3 0.2 2.0 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain OST3_OST6 PF04756.13 CRK37134.1 - 9.1e-16 58.1 0.0 3.7e-07 29.8 0.0 2.2 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 CRK37134.1 - 2.1e-13 50.7 0.0 3.9e-07 30.5 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CRK37134.1 - 4.1e-08 33.4 0.0 0.0047 17.2 0.0 3.3 2 1 1 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.21 CRK37134.1 - 1.1e-06 28.6 0.1 0.059 13.3 0.0 2.3 1 1 1 2 2 2 2 AhpC/TSA family Thioredoxin_7 PF13899.6 CRK37134.1 - 1.5e-06 28.2 0.0 0.087 13.0 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like TraF PF13728.6 CRK37134.1 - 8.3e-05 22.5 0.0 0.28 11.0 0.0 2.4 2 0 0 2 2 2 2 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 CRK37134.1 - 0.00012 21.9 0.0 0.052 13.3 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Glutaredoxin PF00462.24 CRK37134.1 - 0.0015 18.7 1.0 1.6 9.0 0.1 3.3 2 2 0 2 2 2 2 Glutaredoxin HyaE PF07449.11 CRK37134.1 - 0.0055 16.7 0.0 0.065 13.2 0.0 2.5 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.6 CRK37134.1 - 0.016 15.2 0.0 3.2 7.9 0.0 2.7 2 0 0 2 2 2 0 Thioredoxin domain Thioredoxin_6 PF13848.6 CRK37134.1 - 0.025 14.5 0.0 0.74 9.7 0.0 2.6 2 0 0 2 2 2 0 Thioredoxin-like domain DSBA PF01323.20 CRK37134.1 - 0.076 12.8 2.7 16 5.2 0.4 3.3 2 1 1 3 3 3 0 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 CRK37134.1 - 0.076 13.2 5.2 10 6.2 0.1 4.0 3 2 2 5 5 5 0 Thioredoxin Ribosomal_S14 PF00253.21 CRK37135.1 - 6.8e-14 51.4 3.5 1.2e-13 50.6 3.5 1.4 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Penaeidin PF05927.11 CRK37135.1 - 4 8.3 6.5 7.1 7.5 1.1 2.2 1 1 1 2 2 2 0 Penaeidin GTP_EFTU PF00009.27 CRK37136.1 - 5e-57 192.6 0.2 6.9e-57 192.1 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CRK37136.1 - 4.4e-27 94.6 0.0 9.2e-27 93.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CRK37136.1 - 9.5e-16 58.0 4.0 9.5e-16 58.0 4.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CRK37136.1 - 2.1e-05 24.6 0.0 4.1e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CRK37136.1 - 0.0015 18.4 0.0 0.0044 16.9 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase cobW PF02492.19 CRK37136.1 - 0.034 13.7 0.2 0.21 11.1 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 CRK37136.1 - 0.1 12.4 0.1 15 5.3 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF2011 PF09428.10 CRK37137.1 - 9.2e-22 77.1 0.0 2.1e-21 76.0 0.0 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2011) IBR PF01485.21 CRK37137.1 - 1.8e-14 53.7 23.2 2.2e-14 53.4 4.6 3.9 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain DUF5083 PF16890.5 CRK37137.1 - 0.51 10.1 1.7 0.98 9.1 1.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5083) zf-C3HC4 PF00097.25 CRK37137.1 - 0.86 9.5 22.7 0.041 13.7 0.8 3.7 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) EBP PF05241.12 CRK37139.1 - 1.5e-72 242.8 12.0 1.7e-72 242.6 12.0 1.0 1 0 0 1 1 1 1 Emopamil binding protein HemY_N PF07219.13 CRK37139.1 - 5.2 7.3 6.8 2.8 8.2 0.4 2.5 2 0 0 2 2 2 0 HemY protein N-terminus NACHT_N PF17100.5 CRK37141.1 - 5.1e-40 137.7 0.2 5.1e-40 137.7 0.2 2.0 3 0 0 3 3 3 1 N-terminal domain of NWD NACHT-NTPase AAA_16 PF13191.6 CRK37141.1 - 4.7e-06 27.1 0.7 2.2e-05 24.9 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CRK37141.1 - 0.00069 19.9 0.9 0.002 18.4 0.0 2.3 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 CRK37141.1 - 0.002 18.0 0.0 0.0051 16.7 0.0 1.6 1 0 0 1 1 1 1 NACHT domain STAS_2 PF13466.6 CRK37141.1 - 0.0027 18.0 2.2 0.007 16.7 0.3 2.7 2 0 0 2 2 2 1 STAS domain Zn_clus PF00172.18 CRK37142.1 - 3.3e-08 33.5 12.1 5.3e-08 32.9 12.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 CRK37142.1 - 0.00013 20.9 0.1 0.00024 20.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain NAP PF00956.18 CRK37143.1 - 9.6e-14 51.2 1.9 0.00018 20.8 0.0 3.2 1 1 2 3 3 3 3 Nucleosome assembly protein (NAP) Cwf_Cwc_15 PF04889.12 CRK37143.1 - 0.21 11.3 5.3 0.4 10.4 5.3 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein WD40 PF00400.32 CRK37144.1 - 2.4e-39 132.6 24.2 7.1e-08 33.0 0.1 12.9 14 0 0 14 14 14 7 WD domain, G-beta repeat Utp12 PF04003.12 CRK37144.1 - 5.3e-23 81.4 0.0 9.6e-23 80.5 0.0 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 CRK37144.1 - 9.8e-22 77.1 0.0 0.0023 18.2 0.0 10.0 5 2 5 11 11 11 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CRK37144.1 - 8.7e-07 29.0 1.7 0.056 13.3 0.1 5.5 5 2 2 7 7 7 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CRK37144.1 - 1.4e-06 27.5 1.4 2.7 6.9 0.0 5.8 4 2 3 7 7 7 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CRK37144.1 - 0.00017 20.4 2.5 2.2 6.8 0.0 4.2 3 2 1 4 4 4 2 Nucleoporin Nup120/160 WD40_like PF17005.5 CRK37144.1 - 0.00071 19.0 0.0 0.4 10.0 0.0 3.9 4 0 0 4 4 4 1 WD40-like domain Nbas_N PF15492.6 CRK37144.1 - 0.0014 18.0 0.2 2.1 7.6 0.0 3.5 3 2 2 5 5 5 2 Neuroblastoma-amplified sequence, N terminal PALB2_WD40 PF16756.5 CRK37144.1 - 0.12 11.2 0.0 3 6.7 0.0 2.7 3 0 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain WD40 PF00400.32 CRK37145.1 - 6e-06 26.9 1.6 0.023 15.6 0.5 3.8 3 1 0 3 3 3 2 WD domain, G-beta repeat Septin PF00735.18 CRK37146.1 - 3.9e-115 384.0 0.3 5.8e-115 383.4 0.3 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 CRK37146.1 - 2.5e-07 30.8 0.0 5.1e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CRK37146.1 - 5.6e-06 26.4 1.7 2.6e-05 24.2 0.0 2.5 3 0 0 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 CRK37146.1 - 6.7e-06 25.8 3.4 0.00011 21.8 0.1 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 CRK37146.1 - 0.0017 18.6 0.7 0.0054 17.0 0.0 2.2 2 1 0 2 2 2 1 AAA domain Roc PF08477.13 CRK37146.1 - 0.0042 17.3 0.1 0.009 16.2 0.1 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Pox_A32 PF04665.12 CRK37146.1 - 0.0043 16.5 0.1 0.0088 15.5 0.1 1.4 1 0 0 1 1 1 1 Poxvirus A32 protein AIG1 PF04548.16 CRK37146.1 - 0.0089 15.4 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 AIG1 family AAA_25 PF13481.6 CRK37146.1 - 0.0091 15.6 0.2 0.038 13.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.14 CRK37146.1 - 0.016 14.5 0.0 0.024 13.9 0.0 1.5 1 1 0 1 1 1 0 KAP family P-loop domain AAA_16 PF13191.6 CRK37146.1 - 0.016 15.6 1.4 0.056 13.8 0.1 2.5 2 1 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.6 CRK37146.1 - 0.016 14.9 0.0 0.032 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain IIGP PF05049.13 CRK37146.1 - 0.019 14.1 0.0 0.033 13.3 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Ras PF00071.22 CRK37146.1 - 0.019 14.6 0.1 0.056 13.0 0.1 1.8 1 0 0 1 1 1 0 Ras family ABC_tran PF00005.27 CRK37146.1 - 0.031 14.8 0.2 0.1 13.1 0.0 2.0 2 0 0 2 2 2 0 ABC transporter Casc1_N PF15927.5 CRK37146.1 - 0.036 13.8 11.4 0.092 12.4 11.4 1.6 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus NACHT PF05729.12 CRK37146.1 - 0.058 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain FOXP-CC PF16159.5 CRK37146.1 - 0.065 13.9 1.0 0.065 13.9 1.0 2.5 2 1 1 3 3 2 0 FOXP coiled-coil domain T2SSE PF00437.20 CRK37146.1 - 0.068 12.2 0.4 0.27 10.3 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein RNA_helicase PF00910.22 CRK37146.1 - 0.15 12.5 0.0 0.49 10.8 0.0 2.0 2 0 0 2 2 1 0 RNA helicase PduV-EutP PF10662.9 CRK37146.1 - 0.16 11.7 0.4 5.8 6.7 0.4 2.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 CRK37146.1 - 0.7 9.9 7.1 4.9 7.2 0.0 3.1 2 1 1 3 3 3 0 Dynamin family DivIC PF04977.15 CRK37146.1 - 1.2 8.9 6.6 0.39 10.5 2.1 2.5 2 0 0 2 2 2 0 Septum formation initiator Ribosomal_L6e PF01159.19 CRK37146.1 - 1.9 9.0 6.6 8.9 6.9 0.2 3.2 3 0 0 3 3 3 0 Ribosomal protein L6e AAA_11 PF13086.6 CRK37146.1 - 5.7 6.6 7.5 24 4.6 0.1 2.2 2 0 0 2 2 2 0 AAA domain BCDHK_Adom3 PF10436.9 CRK37147.1 - 1.4e-45 155.0 0.0 2.6e-45 154.2 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 CRK37147.1 - 4.7e-06 27.1 0.0 1.1e-05 25.8 0.0 1.7 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CRK37147.1 - 0.0061 16.4 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 CRK37147.1 - 0.089 12.8 0.1 0.62 10.0 0.1 2.2 2 1 0 2 2 2 0 Histidine kinase-like ATPase domain SANT_DAMP1_like PF16282.5 CRK37148.1 - 1.3e-30 105.4 0.0 2.2e-30 104.7 0.0 1.4 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 BCDHK_Adom3 PF10436.9 CRK37149.1 - 1.2e-45 155.3 0.0 2.1e-45 154.4 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 CRK37149.1 - 2.7e-05 24.6 0.0 5.1e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CRK37149.1 - 0.01 15.7 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 CRK37149.1 - 0.012 15.5 0.3 0.35 10.8 0.2 2.8 2 1 0 2 2 2 0 Histidine kinase-like ATPase domain Auxin_repressed PF05564.12 CRK37149.1 - 0.14 12.8 2.0 12 6.6 0.9 2.4 2 0 0 2 2 2 0 Dormancy/auxin associated protein SANT_DAMP1_like PF16282.5 CRK37150.1 - 4.4e-30 103.7 0.0 7.3e-30 103.0 0.0 1.4 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 BUD22 PF09073.10 CRK37151.1 - 0.0012 18.3 23.2 0.0014 18.1 23.2 1.2 1 0 0 1 1 1 1 BUD22 Hid1 PF12722.7 CRK37151.1 - 0.025 12.7 4.1 0.031 12.4 4.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Apo-VLDL-II PF05418.11 CRK37151.1 - 0.15 12.6 0.0 0.25 11.9 0.0 1.3 1 0 0 1 1 1 0 Apovitellenin I (Apo-VLDL-II) PPP4R2 PF09184.11 CRK37151.1 - 0.31 10.6 15.2 0.47 10.0 15.2 1.3 1 0 0 1 1 1 0 PPP4R2 DUF2151 PF10221.9 CRK37151.1 - 1.1 7.8 5.2 1.4 7.4 5.2 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator SAPS PF04499.15 CRK37151.1 - 4.4 6.0 10.4 5.1 5.8 10.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Hexapep_2 PF14602.6 CRK37152.1 - 9.3e-14 50.9 18.0 2.9e-07 30.1 5.6 3.1 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 CRK37152.1 - 2.8e-13 49.0 17.0 1.3e-06 27.9 1.6 3.5 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Mac PF12464.8 CRK37152.1 - 1.4e-11 44.4 0.0 2.6e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Maltose acetyltransferase Zn_clus PF00172.18 CRK37152.1 - 1.2e-09 38.2 7.4 2.3e-09 37.2 7.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PPR_2 PF13041.6 CRK37153.1 - 2.9e-15 56.2 0.3 5.8e-08 32.8 0.1 3.7 2 1 1 3 3 3 3 PPR repeat family PPR PF01535.20 CRK37153.1 - 1.8e-12 46.6 0.9 4.8e-06 26.4 0.0 4.5 4 0 0 4 4 4 2 PPR repeat PPR_3 PF13812.6 CRK37153.1 - 2.2e-09 37.2 0.0 4.6e-08 33.0 0.0 2.8 2 1 2 4 4 4 2 Pentatricopeptide repeat domain PPR_1 PF12854.7 CRK37153.1 - 4.4e-09 35.9 0.0 1.2e-06 28.1 0.0 2.6 2 0 0 2 2 2 2 PPR repeat PPR_long PF17177.4 CRK37153.1 - 5.1e-07 29.3 0.0 9.3e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP Zn_clus PF00172.18 CRK37154.1 - 6.1e-10 39.1 7.3 9.7e-10 38.4 7.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hexapep PF00132.24 CRK37154.1 - 3.1e-07 29.9 1.6 5.3e-07 29.1 1.6 1.4 1 0 0 1 1 1 1 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 CRK37154.1 - 7.3e-07 28.8 1.1 1.1e-06 28.2 1.1 1.3 1 0 0 1 1 1 1 Hexapeptide repeat of succinyl-transferase Acetyltransf_11 PF13720.6 CRK37154.1 - 0.18 12.3 0.1 0.32 11.5 0.1 1.4 1 0 0 1 1 1 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 PPR_2 PF13041.6 CRK37155.1 - 1.8e-16 60.1 0.4 6.6e-09 35.8 0.3 3.4 2 1 1 3 3 3 3 PPR repeat family PPR PF01535.20 CRK37155.1 - 1.8e-12 46.6 0.4 1.7e-06 27.9 0.0 3.6 3 0 0 3 3 3 2 PPR repeat PPR_3 PF13812.6 CRK37155.1 - 4.9e-10 39.3 0.0 1.7e-08 34.4 0.0 2.7 2 1 2 4 4 4 2 Pentatricopeptide repeat domain PPR_1 PF12854.7 CRK37155.1 - 1.5e-09 37.4 0.0 8.1e-07 28.6 0.0 2.7 2 0 0 2 2 2 2 PPR repeat PPR_long PF17177.4 CRK37155.1 - 1.2e-07 31.3 0.0 1.8e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP PPR_2 PF13041.6 CRK37156.1 - 7.7e-08 32.4 0.0 0.00015 21.8 0.0 2.5 1 1 1 2 2 2 2 PPR repeat family PPR_1 PF12854.7 CRK37156.1 - 2e-07 30.6 0.0 0.00011 21.8 0.0 2.5 2 0 0 2 2 2 2 PPR repeat PPR_3 PF13812.6 CRK37156.1 - 2.6e-06 27.4 0.0 9.9e-06 25.5 0.0 1.9 2 0 0 2 2 2 1 Pentatricopeptide repeat domain PPR_long PF17177.4 CRK37156.1 - 0.013 14.9 0.0 0.028 13.8 0.0 1.5 1 0 0 1 1 1 0 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 CRK37156.1 - 0.036 14.3 0.1 0.29 11.5 0.0 2.6 3 0 0 3 3 3 0 PPR repeat SpoIIIAC PF06686.11 CRK37156.1 - 0.057 13.6 0.1 0.12 12.6 0.1 1.5 1 0 0 1 1 1 0 Stage III sporulation protein AC/AD protein family cwf18 PF08315.12 CRK37157.1 - 4.9e-16 59.6 0.2 4.9e-16 59.6 0.2 2.4 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor SUZ PF12752.7 CRK37157.1 - 8.1e-13 48.9 1.2 8.1e-13 48.9 1.2 3.2 3 0 0 3 3 3 1 SUZ domain R3H PF01424.22 CRK37157.1 - 1.5e-09 37.7 0.7 3.6e-07 30.1 0.3 2.6 2 0 0 2 2 2 2 R3H domain MitMem_reg PF13012.6 CRK37158.1 - 0.044 14.2 0.2 0.055 13.9 0.2 1.1 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function RhlB PF12300.8 CRK37158.1 - 0.12 12.6 11.4 0.11 12.7 11.4 1.1 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB FoP_duplication PF13865.6 CRK37158.1 - 1.9 9.1 15.1 2.6 8.6 15.1 1.3 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Ribosomal_L17 PF01196.19 CRK37159.1 - 9.2e-33 113.0 0.1 2.3e-32 111.8 0.1 1.7 1 0 0 1 1 1 1 Ribosomal protein L17 MitMem_reg PF13012.6 CRK37159.1 - 5.3e-18 65.5 0.1 1.9e-17 63.7 0.0 2.0 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.21 CRK37159.1 - 2e-17 63.3 0.0 3.9e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease UTP25 PF06862.12 CRK37160.1 - 3.5e-113 378.9 1.8 1.5e-92 310.8 1.0 2.1 1 1 1 2 2 2 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DEAD PF00270.29 CRK37160.1 - 0.00042 20.1 0.0 0.024 14.4 0.0 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase Drc1-Sld2 PF11719.8 CRK37160.1 - 2.4 7.6 12.3 3.6 7.0 12.3 1.3 1 0 0 1 1 1 0 DNA replication and checkpoint protein Ribosomal_L17 PF01196.19 CRK37161.1 - 1.5e-33 115.6 0.1 2.9e-33 114.6 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L17 AIM5 PF17050.5 CRK37162.1 - 7.3e-23 81.1 5.5 1.6e-22 80.1 0.9 2.8 2 0 0 2 2 2 1 Altered inheritance of mitochondria 5 UBA_4 PF14555.6 CRK37162.1 - 0.12 12.2 0.2 0.42 10.5 0.2 1.9 1 0 0 1 1 1 0 UBA-like domain Apolipoprotein PF01442.18 CRK37162.1 - 0.27 11.1 23.7 0.96 9.3 19.8 2.4 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain YtxH PF12732.7 CRK37162.1 - 6.1 7.4 17.2 0.99 10.0 6.9 3.0 2 1 1 3 3 3 0 YtxH-like protein Aldedh PF00171.22 CRK37163.1 - 3.5e-66 223.6 0.0 2.4e-45 154.9 0.0 2.2 1 1 1 2 2 2 2 Aldehyde dehydrogenase family MRP-S28 PF10213.9 CRK37164.1 - 4.1e-47 159.7 0.1 7e-47 159.0 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein Metal_resist PF13801.6 CRK37164.1 - 0.42 10.8 5.6 1.7 8.8 0.1 3.6 4 0 0 4 4 4 0 Heavy-metal resistance AA_permease PF00324.21 CRK37166.1 - 9.5e-100 334.4 36.0 1.2e-99 334.1 36.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CRK37166.1 - 8.9e-32 110.4 39.7 1.1e-31 110.1 39.7 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2722 PF10846.8 CRK37166.1 - 0.0045 16.0 10.4 0.0045 16.0 10.4 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF2722) DUF3292 PF11696.8 CRK37166.1 - 0.079 11.3 4.0 0.15 10.4 4.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) zf-UBR PF02207.20 CRK37167.1 - 8.3e-15 54.7 4.4 8.3e-15 54.7 4.4 2.7 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) MCM PF00493.23 CRK37168.1 - 4.2e-99 330.2 0.0 4.2e-99 330.2 0.0 1.7 2 0 0 2 2 2 1 MCM P-loop domain MCM2_N PF12619.8 CRK37168.1 - 3.2e-34 118.4 33.9 3.2e-34 118.4 33.9 3.0 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_lid PF17855.1 CRK37168.1 - 4.5e-25 87.9 0.5 2.6e-24 85.5 0.7 2.2 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_OB PF17207.3 CRK37168.1 - 1.2e-23 83.3 0.0 2.2e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_N PF14551.6 CRK37168.1 - 1.7e-15 57.5 0.1 4.7e-15 56.0 0.1 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 CRK37168.1 - 7.5e-08 32.0 0.0 5.7e-06 25.9 0.0 2.6 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CRK37168.1 - 6.2e-06 26.3 0.0 1.3e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 CRK37168.1 - 0.0025 17.7 0.1 0.015 15.1 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CRK37168.1 - 0.0035 17.0 0.2 0.025 14.3 0.2 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.6 CRK37168.1 - 3.7 7.9 5.2 0.58 10.5 0.1 2.4 2 1 0 2 2 2 0 AAA ATPase domain DUF4234 PF14018.6 CRK37169.1 - 0.0088 16.1 0.2 0.15 12.2 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4234) LapA_dom PF06305.11 CRK37169.1 - 0.045 13.6 1.0 0.14 12.0 1.0 1.8 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain PMP1_2 PF08114.11 CRK37169.1 - 0.91 9.3 3.8 0.22 11.3 0.3 1.7 2 0 0 2 2 2 0 ATPase proteolipid family MFS_MOT1 PF16983.5 CRK37171.1 - 1.3e-61 205.9 32.4 6.3e-36 123.2 10.9 3.0 3 0 0 3 3 3 2 Molybdate transporter of MFS superfamily Sulfate_transp PF00916.20 CRK37171.1 - 2.4e-05 23.3 0.6 2.4e-05 23.3 0.6 2.3 2 0 0 2 2 2 1 Sulfate permease family Forkhead PF00250.18 CRK37172.1 - 6e-12 45.7 0.0 1.1e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 CRK37172.1 - 1.7e-05 25.1 0.1 3.5e-05 24.1 0.1 1.5 1 0 0 1 1 1 1 FHA domain Coatomer_E PF04733.14 CRK37174.1 - 1.3e-61 208.6 7.3 1.4e-61 208.4 7.3 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.6 CRK37174.1 - 1.3e-10 41.6 17.6 0.00044 20.7 2.1 3.7 4 0 0 4 4 3 3 Tetratricopeptide repeat ANAPC3 PF12895.7 CRK37174.1 - 1.8e-06 28.0 0.8 0.17 12.1 0.0 3.5 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 CRK37174.1 - 3.9e-05 23.5 0.7 1.3 9.5 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 CRK37174.1 - 0.0006 20.4 16.9 0.0094 16.7 0.7 5.6 6 2 1 7 7 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 CRK37174.1 - 0.00085 19.6 14.1 0.14 12.4 0.5 5.4 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 CRK37174.1 - 0.00086 19.0 2.3 0.4 10.6 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 CRK37174.1 - 0.0066 17.1 11.6 0.32 11.7 0.5 4.2 3 1 2 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 CRK37174.1 - 0.0081 16.7 8.1 1.6 9.5 0.2 4.4 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 CRK37174.1 - 0.015 15.4 13.2 0.032 14.4 0.0 5.2 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 CRK37174.1 - 0.025 14.3 6.1 0.16 11.7 0.5 3.9 4 0 0 4 4 4 0 TPR repeat TPR_4 PF07721.14 CRK37174.1 - 0.25 12.1 21.7 0.17 12.6 1.0 6.0 7 1 0 7 7 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 CRK37174.1 - 0.46 10.7 6.2 0.78 9.9 0.5 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 CRK37174.1 - 0.52 10.5 8.9 32 4.9 0.1 5.0 6 1 1 7 7 7 0 Tetratricopeptide repeat PS_Dcarbxylase PF02666.15 CRK37175.1 - 2.8e-57 193.5 0.0 4.7e-57 192.8 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 CRK37175.1 - 2.4e-38 130.5 0.1 2.9e-18 66.1 0.0 2.6 2 0 0 2 2 2 2 C2 domain ERp29 PF07749.12 CRK37175.1 - 0.57 11.1 2.3 2.1 9.3 0.3 2.7 2 1 1 3 3 3 0 Endoplasmic reticulum protein ERp29, C-terminal domain MFS_1 PF07690.16 CRK37177.1 - 9.2e-14 51.1 31.7 9.2e-14 51.1 31.7 4.3 3 1 1 4 4 4 2 Major Facilitator Superfamily CENP-B_N PF04218.13 CRK37177.1 - 0.071 12.8 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain DUF4143 PF13635.6 CRK37179.1 - 0.0024 18.0 0.0 4.4 7.5 0.0 2.8 3 0 0 3 3 3 2 Domain of unknown function (DUF4143) LRR_6 PF13516.6 CRK37179.1 - 0.081 13.0 0.1 0.081 13.0 0.1 5.3 6 0 0 6 6 6 0 Leucine Rich repeat DUF2992 PF11208.8 CRK37179.1 - 1.7 8.9 16.4 4.2 7.6 16.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) Med19 PF10278.9 CRK37179.1 - 3.1 7.7 15.5 6.1 6.7 15.5 1.5 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 RR_TM4-6 PF06459.12 CRK37179.1 - 6.8 6.4 15.9 14 5.4 15.9 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ribosomal_L5e PF17144.4 CRK37180.1 - 4.2e-81 270.7 0.1 6.7e-81 270.1 0.1 1.3 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 CRK37180.1 - 5.5e-35 120.2 7.5 5.5e-35 120.2 7.5 2.0 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region HAD_2 PF13419.6 CRK37181.1 - 0.019 15.1 0.0 0.045 13.8 0.0 1.7 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase CDP-OH_P_transf PF01066.21 CRK37182.1 - 7.7e-17 61.8 0.3 7.7e-17 61.8 0.3 2.8 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase TauD PF02668.16 CRK37193.1 - 9.7e-05 22.3 0.0 9.7e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family ketoacyl-synt PF00109.26 CRK37199.1 - 9e-09 35.3 0.0 9.7e-09 35.2 0.0 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.23 CRK37199.1 - 0.021 14.2 0.0 0.022 14.1 0.0 1.0 1 0 0 1 1 1 0 Thiolase, N-terminal domain SUI1 PF01253.22 CRK37206.1 - 2.9e-17 63.0 0.9 7e-17 61.7 0.7 1.6 2 0 0 2 2 2 1 Translation initiation factor SUI1 DUF2575 PF10837.8 CRK37206.1 - 0.13 12.6 0.0 0.18 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2575) RDV-p3 PF09231.10 CRK37213.1 - 0.15 9.7 0.0 0.16 9.6 0.0 1.0 1 0 0 1 1 1 0 Rice dwarf virus p3 NAD_binding_8 PF13450.6 CRK37216.1 - 7.8e-08 32.4 0.1 1.1e-07 32.0 0.1 1.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 CRK37216.1 - 0.0075 15.6 0.0 0.0075 15.6 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DNA_pol3_beta PF00712.19 CRK37221.1 - 0.061 13.4 0.0 0.072 13.2 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase III beta subunit, N-terminal domain Amidase PF01425.21 CRK37224.1 - 0.00011 21.3 0.0 0.00013 21.1 0.0 1.0 1 0 0 1 1 1 1 Amidase Fasciclin PF02469.22 CRK37233.1 - 3.7e-24 85.4 0.3 4e-24 85.3 0.3 1.0 1 0 0 1 1 1 1 Fasciclin domain Clathrin PF00637.20 CRK37237.1 - 4.7e-09 36.2 0.0 3e-05 23.9 0.0 2.1 2 0 0 2 2 2 2 Region in Clathrin and VPS Acyl-CoA_dh_1 PF00441.24 CRK37244.1 - 5.2e-19 68.9 0.2 5.5e-19 68.9 0.2 1.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.11 CRK37244.1 - 1.2e-06 28.8 0.0 1.4e-06 28.7 0.0 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Gelsolin PF00626.22 CRK37249.1 - 1.3e-13 50.7 0.0 1.5e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 Gelsolin repeat ERCC4 PF02732.15 CRK37252.1 - 0.00054 20.2 0.0 0.00061 20.0 0.0 1.1 1 0 0 1 1 1 1 ERCC4 domain Ran-binding PF05508.11 CRK37252.1 - 0.17 10.8 0.0 0.2 10.6 0.0 1.1 1 0 0 1 1 1 0 RanGTP-binding protein Dak2 PF02734.17 CRK37257.1 - 2.6e-12 47.0 0.6 3e-12 46.8 0.6 1.1 1 0 0 1 1 1 1 DAK2 domain UPF0444 PF15475.6 CRK37257.1 - 0.053 13.8 1.0 0.071 13.4 0.5 1.5 1 1 0 1 1 1 0 Transmembrane protein C12orf23, UPF0444 ThrE PF06738.12 CRK37259.1 - 7.6e-25 87.7 0.0 8.4e-25 87.5 0.0 1.0 1 0 0 1 1 1 1 Putative threonine/serine exporter SDA1 PF05285.12 CRK37270.1 - 7.5e-25 88.1 16.8 8.2e-25 88.0 16.8 1.0 1 0 0 1 1 1 1 SDA1 Spb1_C PF07780.12 CRK37270.1 - 1.6 8.3 12.5 1.9 8.1 12.5 1.0 1 0 0 1 1 1 0 Spb1 C-terminal domain p450 PF00067.22 CRK37286.1 - 2.1e-22 79.5 0.0 2.2e-22 79.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_trans_2_3 PF13632.6 CRK37291.1 - 0.00069 19.6 4.2 0.00078 19.4 4.2 1.0 1 0 0 1 1 1 1 Glycosyl transferase family group 2 HLH PF00010.26 CRK37297.1 - 4.4e-10 39.4 0.9 1.1e-09 38.1 0.9 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain GIT1_C PF12205.8 CRK37297.1 - 0.023 14.8 2.6 0.15 12.2 2.6 2.0 1 1 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term DivIC PF04977.15 CRK37297.1 - 0.17 11.7 5.9 0.059 13.1 1.1 2.2 1 1 1 2 2 2 0 Septum formation initiator Exo_endo_phos PF03372.23 CRK37305.1 - 0.018 14.6 0.0 0.018 14.6 0.0 1.1 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family MFS_1 PF07690.16 CRK37308.1 - 9.1e-05 21.5 7.7 9.1e-05 21.5 7.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Myb_DNA-bind_5 PF13873.6 CRK37309.1 - 0.0093 16.0 0.2 0.47 10.6 0.2 2.1 1 1 1 2 2 2 1 Myb/SANT-like DNA-binding domain Chordopox_A30L PF06015.12 CRK37309.1 - 0.018 14.8 0.5 0.024 14.4 0.5 1.3 1 1 0 1 1 1 0 Chordopoxvirus A30L protein CENP-F_leu_zip PF10473.9 CRK37309.1 - 0.031 14.3 4.5 0.036 14.1 4.5 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BRE1 PF08647.11 CRK37309.1 - 0.036 14.1 3.3 0.039 14.0 3.3 1.1 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Bromodomain PF00439.25 CRK37312.1 - 7.2e-11 42.0 0.2 9.7e-11 41.6 0.2 1.2 1 0 0 1 1 1 1 Bromodomain Ndc80_HEC PF03801.13 CRK37316.1 - 1.5e-22 79.9 0.7 2.7e-22 79.0 0.7 1.4 1 0 0 1 1 1 1 HEC/Ndc80p family PG_binding_2 PF08823.11 CRK37316.1 - 0.097 13.0 0.1 0.35 11.2 0.0 1.8 2 0 0 2 2 2 0 Putative peptidoglycan binding domain RRM_1 PF00076.22 CRK37320.1 - 4.7e-23 80.8 0.0 1.8e-10 40.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CRK37320.1 - 0.00083 19.2 0.0 0.099 12.5 0.0 2.1 2 0 0 2 2 2 2 Occluded RNA-recognition motif PEX11 PF05648.14 CRK37321.1 - 6.9e-73 244.8 0.5 7.7e-73 244.6 0.5 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) FBPase PF00316.20 CRK37322.1 - 3.6e-70 235.3 0.1 4.9e-70 234.9 0.1 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain DUF1295 PF06966.12 CRK37323.1 - 2.1e-29 102.7 0.1 1.5e-27 96.6 0.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 CRK37323.1 - 0.13 12.2 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 3-oxo-5-alpha-steroid 4-dehydrogenase Homoserine_dh PF00742.19 CRK37324.1 - 1.1e-51 175.2 0.0 1.6e-51 174.7 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 CRK37324.1 - 1.1e-17 64.7 0.0 1.8e-17 64.1 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain AAA_22 PF13401.6 CRK37324.1 - 0.024 14.9 0.0 0.047 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Rcd1 PF04078.13 CRK37325.1 - 1.3e-124 414.6 5.1 1.7e-124 414.3 5.1 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like KA1 PF02149.19 CRK37325.1 - 2e-19 69.1 0.1 4e-19 68.1 0.1 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Cu-oxidase_2 PF07731.14 CRK37326.1 - 2.5e-20 72.6 0.1 7.2e-20 71.1 0.1 1.8 2 0 0 2 2 2 1 Multicopper oxidase SGL PF08450.12 CRK37326.1 - 0.018 14.7 0.0 0.041 13.5 0.0 1.6 1 0 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region G-patch PF01585.23 CRK37326.1 - 0.036 14.0 0.3 0.11 12.4 0.3 1.9 1 0 0 1 1 1 0 G-patch domain PD40 PF07676.12 CRK37326.1 - 0.082 12.9 0.4 0.74 9.8 0.0 2.7 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat GSDH PF07995.11 CRK37326.1 - 0.099 11.9 0.1 0.24 10.7 0.1 1.6 1 0 0 1 1 1 0 Glucose / Sorbosone dehydrogenase Cutinase PF01083.22 CRK37327.1 - 6.5e-17 62.1 0.0 7e-17 62.0 0.0 1.0 1 0 0 1 1 1 1 Cutinase Drc1-Sld2 PF11719.8 CRK37328.1 - 8.7e-100 335.4 21.8 9.9e-100 335.2 21.8 1.0 1 0 0 1 1 1 1 DNA replication and checkpoint protein Pec_lyase_C PF00544.19 CRK37329.1 - 4.6e-13 49.2 5.0 1.1e-09 38.1 1.4 2.1 1 1 1 2 2 2 2 Pectate lyase CBM_1 PF00734.18 CRK37329.1 - 1.6e-10 40.7 9.8 1.6e-10 40.7 9.8 1.9 2 0 0 2 2 2 1 Fungal cellulose binding domain Beta_helix PF13229.6 CRK37329.1 - 4.7e-05 23.3 1.7 0.00014 21.7 1.7 1.8 1 1 0 1 1 1 1 Right handed beta helix region DUF2235 PF09994.9 CRK37330.1 - 3.7e-83 279.2 0.0 2.6e-82 276.4 0.0 2.0 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Palm_thioest PF02089.15 CRK37330.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Amidase PF01425.21 CRK37331.1 - 6.3e-81 272.6 0.0 9.1e-81 272.1 0.0 1.2 1 0 0 1 1 1 1 Amidase ARL6IP6 PF15062.6 CRK37331.1 - 0.13 12.4 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 Haemopoietic lineage transmembrane helix Fungal_trans_2 PF11951.8 CRK37332.1 - 0.077 11.8 0.5 0.15 10.9 0.2 1.6 2 0 0 2 2 2 0 Fungal specific transcription factor domain Methyltransf_23 PF13489.6 CRK37333.1 - 5.5e-21 75.1 0.0 8.7e-21 74.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK37333.1 - 1.4e-14 54.5 0.0 4.2e-14 53.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CRK37333.1 - 3.9e-13 49.9 0.0 1e-12 48.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK37333.1 - 3.3e-10 40.6 0.0 2.4e-09 37.8 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK37333.1 - 1.2e-07 31.7 0.0 5.4e-07 29.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CRK37333.1 - 7.3e-05 22.2 0.0 0.0019 17.6 0.0 2.5 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 CRK37333.1 - 0.00062 19.1 0.0 0.0017 17.7 0.0 1.7 1 1 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 CRK37333.1 - 0.00082 19.0 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 CRK37333.1 - 0.0011 18.4 0.0 0.0017 17.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 CRK37333.1 - 0.0031 17.3 0.0 0.0048 16.7 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_4 PF02390.17 CRK37333.1 - 0.055 12.9 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase DUF938 PF06080.12 CRK37333.1 - 0.099 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) FtsJ PF01728.19 CRK37333.1 - 0.16 12.0 0.0 0.34 11.0 0.0 1.5 2 0 0 2 2 2 0 FtsJ-like methyltransferase RTA1 PF04479.13 CRK37334.1 - 2.3e-55 187.4 9.9 8.9e-40 136.5 5.6 2.4 2 1 1 3 3 3 2 RTA1 like protein DUF5134 PF17197.4 CRK37334.1 - 0.1 12.5 4.0 1.4 8.8 4.0 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF5134) Glyco_hydro_85 PF03644.13 CRK37334.1 - 0.3 10.5 0.1 0.43 10.0 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 85 SRTM1 PF15872.5 CRK37334.1 - 2.4 8.4 3.8 21 5.3 0.2 2.9 3 0 0 3 3 3 0 Serine-rich and transmembrane domain-containing protein 1 RTA1 PF04479.13 CRK37335.1 - 3.6e-69 232.5 13.3 3.6e-69 232.5 13.3 1.8 2 0 0 2 2 2 1 RTA1 like protein Fungal_trans_2 PF11951.8 CRK37336.1 - 3.7e-10 39.2 0.2 5.3e-10 38.7 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK37336.1 - 1.3e-09 38.0 8.1 2.2e-09 37.3 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Intg_mem_TP0381 PF09529.10 CRK37336.1 - 0.77 9.2 3.6 9.6 5.6 0.1 2.2 2 0 0 2 2 2 0 Integral membrane protein (intg_mem_TP0381) MBOAT_2 PF13813.6 CRK37337.1 - 4.5e-15 55.7 2.8 1.5e-14 54.0 2.8 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Myb_DNA-bind_6 PF13921.6 CRK37340.1 - 0.00023 21.4 0.2 0.00036 20.7 0.2 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 CRK37340.1 - 0.056 13.6 1.0 0.094 12.9 1.0 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain WW PF00397.26 CRK37341.1 - 2.9e-13 49.6 6.3 7.2e-13 48.4 6.3 1.7 1 0 0 1 1 1 1 WW domain KinB_sensor PF16767.5 CRK37341.1 - 0.19 12.2 1.1 0.48 10.9 1.1 1.5 1 0 0 1 1 1 0 Sensor domain of alginate biosynthesis sensor protein KinB CYSTM PF12734.7 CRK37342.1 - 0.0027 18.0 67.2 0.06 13.7 45.4 3.9 1 1 1 2 2 2 1 Cysteine-rich TM module stress tolerance EF-hand_1 PF00036.32 CRK37343.1 - 1.9e-37 124.0 6.6 8.3e-10 37.5 2.3 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CRK37343.1 - 2.7e-31 107.8 3.6 1.2e-16 60.9 0.4 2.0 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CRK37343.1 - 7.4e-31 103.4 1.0 1.1e-07 31.1 0.0 4.1 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 CRK37343.1 - 3.6e-27 94.0 9.7 2.3e-14 53.0 0.3 3.9 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 CRK37343.1 - 3.8e-24 83.0 6.7 5e-06 25.8 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 CRK37343.1 - 5.9e-13 48.9 0.1 1e-05 25.8 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 CRK37343.1 - 9e-07 28.8 4.0 0.027 14.4 0.1 3.0 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CRK37343.1 - 1.1e-05 25.8 0.0 0.052 13.9 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_14 PF17959.1 CRK37343.1 - 0.00014 22.1 0.1 0.34 11.3 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_11 PF08976.11 CRK37343.1 - 0.00018 22.3 0.0 0.005 17.7 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain Dockerin_1 PF00404.18 CRK37343.1 - 0.00055 20.1 0.5 0.39 11.0 0.2 2.5 2 1 0 2 2 2 2 Dockerin type I domain Caleosin PF05042.13 CRK37343.1 - 0.053 13.4 0.0 0.79 9.6 0.0 2.5 2 2 0 2 2 2 0 Caleosin related protein EFhand_Ca_insen PF08726.10 CRK37343.1 - 0.062 13.4 0.0 0.22 11.7 0.0 1.9 2 0 0 2 2 2 0 Ca2+ insensitive EF hand SurA_N_3 PF13624.6 CRK37343.1 - 0.069 12.9 0.0 0.53 10.1 0.0 2.0 2 0 0 2 2 2 0 SurA N-terminal domain DUF1128 PF06569.11 CRK37343.1 - 0.081 12.9 0.5 5.3 7.1 0.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1128) DUF5580 PF17743.1 CRK37343.1 - 0.082 11.4 0.0 0.17 10.4 0.0 1.4 1 1 1 2 2 2 0 Family of unknown function (DUF5580) DUF5470 PF17564.2 CRK37343.1 - 0.097 12.9 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5470) VCBS PF13517.6 CRK37343.1 - 3 8.5 5.9 1.1e+02 3.5 5.1 2.9 2 1 1 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Peptidase_C14 PF00656.22 CRK37344.1 - 4.1e-61 207.1 0.0 5.1e-61 206.8 0.0 1.1 1 0 0 1 1 1 1 Caspase domain COesterase PF00135.28 CRK37345.1 - 4.6e-74 250.1 0.0 6e-74 249.7 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CRK37345.1 - 5.8e-13 49.2 0.1 1.5e-12 47.8 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CRK37345.1 - 0.017 14.6 0.1 0.029 13.9 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Lectin_C PF00059.21 CRK37345.1 - 0.17 12.7 0.4 0.54 11.0 0.1 2.0 2 0 0 2 2 2 0 Lectin C-type domain Say1_Mug180 PF10340.9 CRK37345.1 - 0.24 10.2 0.1 0.41 9.4 0.1 1.4 1 1 0 1 1 1 0 Steryl acetyl hydrolase Methyltransf_25 PF13649.6 CRK37346.1 - 8e-11 42.5 0.1 2.2e-10 41.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 CRK37346.1 - 1.2e-10 41.3 0.0 1.8e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 CRK37346.1 - 1.1e-09 38.2 0.0 1.7e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CRK37346.1 - 2.7e-07 31.1 0.0 6.4e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CRK37346.1 - 7.4e-06 25.9 0.0 1.2e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 CRK37346.1 - 9.8e-06 24.7 0.3 1.8e-05 23.9 0.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) Methyltransf_18 PF12847.7 CRK37346.1 - 5.8e-05 23.1 0.1 9.6e-05 22.3 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 CRK37346.1 - 0.0015 17.9 0.0 0.0021 17.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 CRK37346.1 - 0.0016 18.0 0.1 0.0026 17.4 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PRMT5 PF05185.16 CRK37346.1 - 0.0089 15.9 0.1 0.02 14.7 0.1 1.6 1 1 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 CRK37346.1 - 0.0091 15.9 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Methyltransf_12 PF08242.12 CRK37346.1 - 0.0097 16.6 0.0 0.017 15.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 CRK37346.1 - 0.02 14.9 0.0 0.035 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 CRK37346.1 - 0.044 13.5 0.2 0.067 12.9 0.2 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 CRK37346.1 - 0.049 13.4 0.0 0.074 12.8 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_24 PF13578.6 CRK37346.1 - 0.057 14.4 0.0 0.14 13.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain p450 PF00067.22 CRK37347.1 - 7.4e-70 236.0 0.0 2e-62 211.5 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 zf-RING_2 PF13639.6 CRK37348.1 - 8.8e-11 42.0 3.4 1.6e-10 41.1 3.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 CRK37348.1 - 3.3e-09 36.9 2.5 8.3e-09 35.6 2.5 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CRK37348.1 - 7.9e-07 29.1 0.5 1.6e-06 28.0 0.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 CRK37348.1 - 1.5e-05 24.7 6.7 4.3e-05 23.3 6.7 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CRK37348.1 - 1.7e-05 24.7 2.3 2.9e-05 23.9 2.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CRK37348.1 - 5.3e-05 23.2 1.1 0.00011 22.1 0.5 1.9 1 1 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 CRK37348.1 - 0.0001 22.1 2.2 0.00018 21.3 2.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 CRK37348.1 - 0.00014 21.7 2.6 0.00024 20.9 2.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CRK37348.1 - 0.00022 21.0 2.1 0.00047 20.0 2.1 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CRK37348.1 - 0.011 15.4 1.0 0.011 15.4 1.0 1.5 2 0 0 2 2 1 0 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 CRK37348.1 - 0.018 14.8 0.6 0.057 13.2 0.6 1.9 1 1 0 1 1 1 0 RING-like zinc finger FANCL_C PF11793.8 CRK37348.1 - 0.024 14.8 4.5 0.74 10.0 4.5 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain Rtf2 PF04641.12 CRK37348.1 - 0.061 12.7 3.7 0.075 12.4 2.1 1.9 2 1 0 2 2 2 0 Rtf2 RING-finger zf-Nse PF11789.8 CRK37348.1 - 0.12 12.3 0.7 0.25 11.2 0.7 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 CRK37348.1 - 0.72 10.1 2.9 0.39 10.9 0.4 1.9 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING Cullin PF00888.22 CRK37350.1 - 1.8e-22 79.7 6.0 2.9e-22 79.1 6.0 1.2 1 0 0 1 1 1 1 Cullin family ANAPC2 PF08672.11 CRK37350.1 - 4.1e-21 75.2 0.2 1.7e-20 73.2 0.2 2.2 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 Pinin_SDK_memA PF04696.13 CRK37350.1 - 1.4e-15 57.5 9.9 1.4e-15 57.5 9.9 2.6 2 0 0 2 2 2 1 pinin/SDK/memA/ protein conserved region SPX PF03105.19 CRK37350.1 - 0.39 10.6 15.1 0.53 10.1 0.6 2.4 2 0 0 2 2 2 0 SPX domain Pex26 PF07163.12 CRK37350.1 - 1.3 8.3 10.1 0.019 14.3 2.6 1.7 2 0 0 2 2 2 0 Pex26 protein PHF5 PF03660.14 CRK37351.1 - 1.2e-51 173.3 11.0 1.3e-51 173.1 11.0 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 CRK37351.1 - 0.42 8.4 6.8 0.44 8.4 6.8 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DZR PF12773.7 CRK37351.1 - 1 9.4 16.6 3 7.9 2.4 2.9 1 1 1 2 2 2 0 Double zinc ribbon CAF1 PF04857.20 CRK37352.1 - 1.7e-54 185.2 0.0 2e-54 185.0 0.0 1.0 1 0 0 1 1 1 1 CAF1 family ribonuclease Sedlin_N PF04628.13 CRK37352.1 - 0.13 12.4 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Sedlin, N-terminal conserved region zf-rbx1 PF12678.7 CRK37354.1 - 2.5e-16 59.7 28.3 1.8e-07 31.3 0.9 5.8 6 0 0 6 6 5 4 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CRK37354.1 - 8.1e-16 58.1 46.0 1.2e-07 32.0 1.3 6.6 6 0 0 6 6 6 2 Ring finger domain PHD PF00628.29 CRK37354.1 - 9e-15 54.3 34.9 4.9e-08 32.7 4.9 4.7 4 0 0 4 4 4 2 PHD-finger Prok-RING_4 PF14447.6 CRK37354.1 - 3.3e-11 42.8 18.7 1.1e-05 25.2 1.0 4.9 4 0 0 4 4 4 2 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 CRK37354.1 - 2.1e-09 37.2 19.4 0.00012 22.0 0.6 5.5 6 0 0 6 6 5 2 zinc-RING finger domain PHD_2 PF13831.6 CRK37354.1 - 1e-07 31.4 33.5 8.9e-05 22.0 3.9 4.4 4 0 0 4 4 4 2 PHD-finger zf-C3HC4_3 PF13920.6 CRK37354.1 - 1.1e-05 25.2 7.6 0.00096 19.0 0.9 6.8 6 2 0 6 6 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CRK37354.1 - 1.3e-05 24.9 10.5 0.0007 19.4 1.8 6.2 6 0 0 6 6 6 2 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CRK37354.1 - 2.8e-05 24.1 29.8 0.0084 16.1 1.5 5.4 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 CRK37354.1 - 3.3e-05 23.7 17.1 0.00077 19.3 4.6 6.0 4 4 2 6 6 4 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.6 CRK37354.1 - 0.00048 20.0 25.2 0.039 13.9 2.3 4.8 5 0 0 5 5 4 2 Prokaryotic RING finger family 1 zf-PHD-like PF15446.6 CRK37354.1 - 0.00048 19.8 15.8 0.023 14.3 1.0 3.7 4 0 0 4 4 4 2 PHD/FYVE-zinc-finger like domain Zn_ribbon_17 PF17120.5 CRK37354.1 - 0.0012 18.4 28.6 0.014 15.0 1.9 4.5 4 0 0 4 4 4 2 Zinc-ribbon, C4HC2 type CDC24_OB3 PF17244.2 CRK37354.1 - 0.015 15.0 0.5 5.5 6.6 0.1 2.3 2 0 0 2 2 2 0 Cell division control protein 24, OB domain 3 zf-UDP PF14569.6 CRK37354.1 - 0.019 15.1 7.6 1.3 9.1 0.0 3.4 4 0 0 4 4 2 0 Zinc-binding RING-finger BRK PF07533.16 CRK37354.1 - 0.019 14.6 3.7 2.9 7.6 0.3 2.3 2 0 0 2 2 2 0 BRK domain zf-FPG_IleRS PF06827.14 CRK37354.1 - 0.038 13.9 7.2 24 4.9 0.0 4.9 4 0 0 4 4 4 0 Zinc finger found in FPG and IleRS zf-RING_6 PF14835.6 CRK37354.1 - 0.045 13.6 7.8 2 8.4 0.2 3.3 4 0 0 4 4 2 0 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 CRK37354.1 - 0.14 12.3 7.5 3.9 7.7 0.2 3.2 3 0 0 3 3 2 0 zinc RING finger of MSL2 DUF2847 PF11009.8 CRK37354.1 - 0.17 11.8 0.1 33 4.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2847) zinc_ribbon_16 PF17034.5 CRK37354.1 - 0.38 11.0 5.7 19 5.5 0.3 3.7 3 0 0 3 3 3 0 Zinc-ribbon like family Tmpp129 PF10272.9 CRK37354.1 - 0.9 8.8 7.5 7.8 5.7 0.9 2.6 2 0 0 2 2 2 0 Putative transmembrane protein precursor zf-Di19 PF05605.12 CRK37354.1 - 0.93 9.8 11.0 40 4.6 0.0 4.4 4 0 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_5 PF13719.6 CRK37354.1 - 1.2 8.9 3.7 39 4.1 0.3 3.1 2 0 0 2 2 2 0 zinc-ribbon domain Rad50_zn_hook PF04423.14 CRK37354.1 - 1.9 8.4 9.8 12 5.9 0.0 3.9 4 0 0 4 4 4 0 Rad50 zinc hook motif DUF282 PF03380.14 CRK37354.1 - 2.2 8.3 14.0 8.3 6.4 3.2 2.9 2 0 0 2 2 2 0 Caenorhabditis protein of unknown function, DUF282 Zn-ribbon_8 PF09723.10 CRK37354.1 - 7.2 6.8 15.5 19 5.4 0.3 5.0 4 0 0 4 4 4 0 Zinc ribbon domain MRP-L46 PF11788.8 CRK37355.1 - 2e-25 89.8 0.0 2e-25 89.8 0.0 3.6 4 2 1 5 5 5 1 39S mitochondrial ribosomal protein L46 PHD PF00628.29 CRK37355.1 - 2.9e-08 33.5 4.9 5.1e-08 32.7 4.9 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 CRK37355.1 - 5.7e-05 22.6 3.9 9.2e-05 21.9 3.9 1.3 1 0 0 1 1 1 1 PHD-finger zf-PHD-like PF15446.6 CRK37355.1 - 0.01 15.5 1.0 0.024 14.3 1.0 1.6 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain Prok-RING_1 PF14446.6 CRK37355.1 - 0.02 14.8 2.3 0.04 13.8 2.3 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 C1_2 PF03107.16 CRK37355.1 - 0.16 12.3 0.5 0.37 11.2 0.5 1.6 1 0 0 1 1 1 0 C1 domain MRP-L46 PF11788.8 CRK37356.1 - 4.4e-26 92.0 0.0 7.3e-26 91.2 0.0 1.4 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 DUF3535 PF12054.8 CRK37357.1 - 1.7e-115 386.7 6.9 1.4e-113 380.5 4.0 3.3 2 1 0 2 2 2 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 CRK37357.1 - 1.7e-43 148.7 0.0 2.9e-43 147.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain CDC37_M PF08565.11 CRK37357.1 - 8.2e-39 132.2 0.3 4.7e-38 129.8 0.1 2.3 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 CRK37357.1 - 7.8e-29 99.7 1.0 2.5e-28 98.1 0.4 2.3 2 0 0 2 2 2 1 Cdc37 C terminal domain Helicase_C PF00271.31 CRK37357.1 - 9.8e-19 67.7 0.0 3.9e-18 65.8 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.22 CRK37357.1 - 2.9e-09 36.4 7.8 0.53 10.7 0.1 6.5 6 0 0 6 6 5 4 HEAT repeat Vac14_Fab1_bd PF12755.7 CRK37357.1 - 7.9e-08 32.8 0.9 0.38 11.4 0.0 4.3 3 1 1 4 4 4 3 Vacuolar 14 Fab1-binding region CDC37_N PF03234.14 CRK37357.1 - 0.00025 22.0 0.2 0.0026 18.6 0.1 2.8 1 1 1 2 2 2 1 Cdc37 N terminal kinase binding CLASP_N PF12348.8 CRK37357.1 - 0.019 14.5 0.2 7.7 6.0 0.0 3.6 5 0 0 5 5 5 0 CLASP N terminal DUF4075 PF13294.6 CRK37357.1 - 0.069 13.3 1.4 0.17 12.0 1.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4075) Adaptin_N PF01602.20 CRK37357.1 - 0.42 9.1 2.5 1.4 7.4 0.2 2.8 3 1 0 3 3 3 0 Adaptin N terminal region DUF3535 PF12054.8 CRK37358.1 - 3.7e-130 435.1 0.6 3.9e-129 431.7 1.0 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 CRK37358.1 - 6.7e-65 219.1 0.0 1.4e-64 218.1 0.0 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CRK37358.1 - 7.3e-19 68.2 0.0 3.1e-18 66.1 0.0 2.1 3 0 0 3 3 2 1 Helicase conserved C-terminal domain HEAT PF02985.22 CRK37358.1 - 5e-16 57.4 10.0 0.0034 17.5 0.0 8.5 8 0 0 8 8 7 5 HEAT repeat Vac14_Fab1_bd PF12755.7 CRK37358.1 - 1.4e-08 35.2 0.6 0.29 11.7 0.0 4.5 3 1 1 4 4 4 3 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 CRK37358.1 - 1.6e-08 34.8 5.2 0.0013 19.1 0.0 6.4 6 0 0 6 6 6 1 HEAT repeats HEAT_EZ PF13513.6 CRK37358.1 - 0.0035 17.8 11.1 13 6.4 0.0 7.9 9 0 0 9 9 9 1 HEAT-like repeat CLASP_N PF12348.8 CRK37358.1 - 0.0077 15.8 0.4 2.3 7.7 0.0 3.3 3 0 0 3 3 3 1 CLASP N terminal Cnd1 PF12717.7 CRK37358.1 - 0.035 14.1 0.0 2.3 8.2 0.0 3.2 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 BLM10_mid PF16507.5 CRK37358.1 - 0.042 12.5 0.0 7.1 5.1 0.0 3.0 3 0 0 3 3 3 0 Proteasome-substrate-size regulator, mid region Adaptin_N PF01602.20 CRK37358.1 - 0.2 10.2 2.6 1 7.8 0.2 3.0 3 1 0 3 3 3 0 Adaptin N terminal region SMC_N PF02463.19 CRK37359.1 - 5.1e-60 202.6 18.9 1.1e-59 201.5 18.9 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CRK37359.1 - 1.8e-28 99.2 0.1 1.1e-27 96.6 0.0 2.4 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 CRK37359.1 - 2.7e-18 66.8 1.5 2e-09 37.7 0.1 3.1 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 CRK37359.1 - 2.4e-12 47.2 58.6 2e-09 37.7 19.8 4.5 2 2 1 3 3 3 2 AAA ATPase domain AAA_23 PF13476.6 CRK37359.1 - 5.5e-08 33.6 46.9 5.5e-08 33.6 46.9 7.3 2 2 2 4 4 2 1 AAA domain SbcCD_C PF13558.6 CRK37359.1 - 0.00059 20.0 0.1 0.0023 18.1 0.1 2.1 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 CRK37359.1 - 0.0011 18.6 0.0 0.0028 17.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Baculo_PEP_C PF04513.12 CRK37359.1 - 0.0075 16.3 28.0 1.6 8.8 3.0 6.4 4 1 1 6 6 6 3 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 CRK37359.1 - 0.24 11.5 53.8 0.42 10.7 0.5 8.1 5 2 4 9 9 9 0 Protein of unknown function (DUF1664) ABC_tran PF00005.27 CRK37359.1 - 0.33 11.5 0.0 0.33 11.5 0.0 6.1 3 2 0 3 3 1 0 ABC transporter PCI PF01399.27 CRK37359.1 - 0.9 10.1 4.7 2.1 8.9 1.0 3.3 2 1 0 2 2 2 0 PCI domain BLOC1_2 PF10046.9 CRK37359.1 - 4.3 7.7 55.6 0.27 11.6 2.8 8.1 5 2 1 7 7 7 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DEAD PF00270.29 CRK37360.1 - 8.3e-40 136.4 0.5 1.3e-39 135.8 0.5 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CRK37360.1 - 3.3e-31 107.9 0.1 9.3e-31 106.5 0.1 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CRK37360.1 - 2.8e-06 27.5 0.1 1.1e-05 25.5 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit YL1 PF05764.13 CRK37360.1 - 0.00054 20.1 5.3 0.00054 20.1 5.3 2.0 3 0 0 3 3 3 1 YL1 nuclear protein AAA_19 PF13245.6 CRK37360.1 - 0.018 15.3 0.6 0.033 14.5 0.6 1.6 1 1 0 1 1 1 0 AAA domain MCM_bind PF09739.9 CRK37360.1 - 0.56 8.6 3.5 2.2 6.6 0.0 2.1 2 0 0 2 2 2 0 Mini-chromosome maintenance replisome factor CMS1 PF14617.6 CRK37360.1 - 0.64 9.3 6.4 3.4 7.0 0.0 2.6 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit DUF4602 PF15375.6 CRK37361.1 - 0.0019 18.5 8.1 0.021 15.1 8.1 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4602) DEAD PF00270.29 CRK37362.1 - 1.4e-39 135.6 0.6 2.2e-39 135.0 0.6 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CRK37362.1 - 2.8e-21 75.9 0.4 7.8e-21 74.5 0.2 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CRK37362.1 - 8.2e-07 29.2 0.1 3.6e-06 27.1 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit YL1 PF05764.13 CRK37362.1 - 0.00025 21.3 1.5 0.00034 20.8 0.3 1.8 2 0 0 2 2 2 1 YL1 nuclear protein AAA_19 PF13245.6 CRK37362.1 - 0.0082 16.5 0.7 0.013 15.8 0.7 1.6 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 CRK37362.1 - 0.083 12.4 1.6 0.3 10.5 0.2 2.0 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain MCM_bind PF09739.9 CRK37362.1 - 0.63 8.4 4.0 1.7 7.0 0.0 2.1 2 0 0 2 2 2 0 Mini-chromosome maintenance replisome factor CMS1 PF14617.6 CRK37362.1 - 5.9 6.2 9.1 4 6.7 0.0 2.3 2 1 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit DUF2890 PF11081.8 CRK37363.1 - 0.002 18.3 2.7 0.0031 17.6 2.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2890) STE PF02200.16 CRK37364.1 - 2.1e-53 179.4 0.1 3.5e-53 178.7 0.1 1.3 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.26 CRK37364.1 - 3.4e-09 36.6 15.5 0.00033 20.9 3.8 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CRK37364.1 - 6.3e-05 23.5 11.3 0.069 14.0 2.0 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 CRK37364.1 - 0.053 13.7 0.1 16 5.6 0.0 2.3 2 0 0 2 2 2 0 Aberrant zinc-finger zf-C2H2_6 PF13912.6 CRK37364.1 - 7.7 6.6 6.9 34 4.6 0.7 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger SMC_hinge PF06470.13 CRK37366.1 - 1.6e-28 99.3 0.1 1.2e-27 96.6 0.0 2.5 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain SMC_N PF02463.19 CRK37366.1 - 5.7e-17 61.9 31.2 1.2e-16 60.8 31.2 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CRK37366.1 - 8.4e-10 38.9 0.1 4.2e-09 36.6 0.1 2.0 1 1 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 CRK37366.1 - 0.00065 19.9 0.1 0.0023 18.1 0.1 2.0 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 CRK37366.1 - 0.00081 19.2 6.8 0.00081 19.2 6.8 3.3 2 1 1 3 3 3 1 AAA ATPase domain DivIC PF04977.15 CRK37366.1 - 0.0029 17.3 1.1 0.0029 17.3 1.1 10.0 8 2 2 10 10 10 1 Septum formation initiator Cortex-I_coil PF09304.10 CRK37366.1 - 0.0071 16.6 7.1 0.0071 16.6 7.1 7.7 3 2 3 7 7 7 1 Cortexillin I, coiled coil Abi_C PF14355.6 CRK37366.1 - 0.098 12.8 9.1 18 5.5 0.0 5.4 6 0 0 6 6 5 0 Abortive infection C-terminus DUF1664 PF07889.12 CRK37366.1 - 0.19 11.8 49.4 0.3 11.1 0.5 7.8 3 2 2 8 8 8 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 CRK37366.1 - 0.21 11.9 42.7 0.15 12.4 1.6 7.1 4 2 2 7 7 7 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Baculo_PEP_C PF04513.12 CRK37366.1 - 0.89 9.6 28.5 6 6.9 0.3 6.6 4 2 2 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2730 PF10805.8 CRK37366.1 - 2.8 8.1 26.3 1.9 8.6 0.1 6.2 5 1 0 6 6 5 0 Protein of unknown function (DUF2730) CCP_MauG PF03150.14 CRK37366.1 - 6.4 7.4 12.1 8.8 7.0 0.0 4.5 5 0 0 5 5 5 0 Di-haem cytochrome c peroxidase DUF2935 PF11155.8 CRK37366.1 - 8.6 6.7 14.3 2.4 8.5 2.4 4.6 3 2 0 3 3 3 0 Domain of unknown function (DUF2935) STE PF02200.16 CRK37367.1 - 2.7e-51 172.6 0.1 3.9e-51 172.1 0.1 1.2 1 0 0 1 1 1 1 STE like transcription factor DUF938 PF06080.12 CRK37367.1 - 0.0033 17.2 0.3 0.0068 16.2 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF938) DUF2278 PF10042.9 CRK37367.1 - 0.14 12.2 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2278) Bac_rhamnosid6H PF17389.2 CRK37368.1 - 1.7e-118 395.8 0.0 2.2e-118 395.4 0.0 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 CRK37368.1 - 2.6e-48 164.1 0.1 5.3e-48 163.1 0.1 1.6 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid PF05592.11 CRK37368.1 - 3.4e-24 84.8 0.0 7.9e-24 83.6 0.0 1.7 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Bac_rhamnosid_C PF17390.2 CRK37368.1 - 4e-18 65.0 0.0 9.1e-18 63.8 0.0 1.6 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain BTRD1 PF17660.1 CRK37368.1 - 0.048 13.5 0.0 0.16 11.8 0.0 1.9 1 0 0 1 1 1 0 Bacterial tandem repeat domain 1 Glyco_hydro_36 PF17167.4 CRK37368.1 - 0.052 12.2 0.0 0.081 11.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase 36 superfamily, catalytic domain Sugar_tr PF00083.24 CRK37369.1 - 1.3e-74 251.8 19.0 1.5e-74 251.5 19.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK37369.1 - 3.8e-16 59.0 33.0 7.1e-09 35.0 21.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 CRK37369.1 - 0.0087 15.0 7.9 0.024 13.5 2.9 2.9 2 1 1 3 3 3 1 MFS_1 like family Bac_rhamnosid6H PF17389.2 CRK37371.1 - 9.2e-118 393.4 0.0 1.3e-117 392.9 0.0 1.2 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 CRK37371.1 - 1e-47 162.1 0.2 3.1e-47 160.6 0.1 1.8 2 0 0 2 2 2 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid PF05592.11 CRK37371.1 - 3.3e-24 84.8 0.0 1.1e-23 83.1 0.0 1.9 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Sugar_tr PF00083.24 CRK37372.1 - 7.4e-75 252.5 17.5 8.6e-75 252.3 17.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK37372.1 - 3.2e-14 52.6 30.6 5.9e-07 28.7 18.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1899 PF08953.11 CRK37373.1 - 3.3e-39 132.6 0.0 2.1e-26 91.5 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF1899) WD40_4 PF16300.5 CRK37373.1 - 2.1e-38 130.0 4.8 2.4e-18 65.7 0.4 2.8 2 0 0 2 2 2 2 Type of WD40 repeat WD40 PF00400.32 CRK37373.1 - 1.2e-16 60.8 12.8 0.00018 22.2 0.4 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK37373.1 - 4e-08 33.4 0.0 0.042 14.2 0.0 4.0 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain TMEM192 PF14802.6 CRK37373.1 - 2.3e-06 26.9 0.0 0.041 13.0 0.0 2.2 2 0 0 2 2 2 2 TMEM192 family FliT PF05400.13 CRK37373.1 - 0.0038 18.0 0.2 5.5 7.9 0.0 2.6 2 0 0 2 2 2 2 Flagellar protein FliT DUF1664 PF07889.12 CRK37373.1 - 0.011 15.7 1.1 3.7 7.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Phage_Mu_Gam PF07352.12 CRK37373.1 - 0.018 15.0 3.4 0.93 9.4 0.2 2.3 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein Nup160 PF11715.8 CRK37373.1 - 0.023 13.4 0.4 4.7 5.7 0.1 2.4 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 CRK37373.1 - 0.046 12.7 0.0 36 3.2 0.0 3.1 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF16 PF01519.16 CRK37373.1 - 0.052 14.0 3.1 4.4 7.9 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF812 PF05667.11 CRK37373.1 - 0.096 11.6 3.7 2.5 6.9 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF812) MmlI PF09448.10 CRK37373.1 - 0.21 12.1 0.2 20 5.6 0.0 2.6 2 0 0 2 2 2 0 Methylmuconolactone methyl-isomerase TolA_bind_tri PF16331.5 CRK37373.1 - 0.64 10.1 6.4 4.9 7.3 0.3 2.6 2 0 0 2 2 2 0 TolA binding protein trimerisation MAD PF05557.13 CRK37373.1 - 0.91 7.8 5.3 2.8 6.2 0.2 2.1 2 0 0 2 2 2 0 Mitotic checkpoint protein DAAD PF18752.1 CRK37373.1 - 1.2 9.0 12.3 4.2 7.1 2.1 2.5 2 0 0 2 2 2 0 Dictyosteliid AID/APOBEC-like Deaminase TRAF_BIRC3_bd PF16673.5 CRK37373.1 - 1.2 8.9 5.4 15 5.5 0.6 2.4 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain DUF148 PF02520.17 CRK37373.1 - 1.5 9.0 6.2 15 5.8 0.9 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF148 Spc7 PF08317.11 CRK37373.1 - 1.8 7.4 6.5 5.6 5.8 0.6 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein Tropomyosin PF00261.20 CRK37373.1 - 2 7.7 5.9 11 5.3 0.6 2.4 2 0 0 2 2 2 0 Tropomyosin CENP-K PF11802.8 CRK37373.1 - 3.4 7.1 5.4 3.3 7.2 0.2 2.2 2 0 0 2 2 2 0 Centromere-associated protein K HOOK PF05622.12 CRK37373.1 - 4.2 5.4 6.0 4.7 5.2 0.5 2.1 2 0 0 2 2 2 0 HOOK protein JIP_LZII PF16471.5 CRK37373.1 - 4.6 7.5 7.4 6.5 7.0 0.8 2.4 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II PH PF00169.29 CRK37374.1 - 3.1e-11 43.7 0.0 7.9e-11 42.4 0.0 1.7 1 1 0 1 1 1 1 PH domain PH_11 PF15413.6 CRK37374.1 - 0.0012 19.2 0.0 0.0027 18.1 0.0 1.6 1 1 0 1 1 1 1 Pleckstrin homology domain YkyB PF14177.6 CRK37374.1 - 0.18 12.1 0.0 0.3 11.4 0.0 1.3 1 0 0 1 1 1 0 YkyB-like protein His_biosynth PF00977.21 CRK37376.1 - 5.2e-34 117.7 0.0 6.3e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein Ribul_P_3_epim PF00834.19 CRK37376.1 - 0.018 14.5 0.1 0.028 13.8 0.1 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family RVP PF00077.20 CRK37376.1 - 0.12 12.7 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease HET PF06985.11 CRK37377.1 - 6.2e-20 72.0 0.1 2.6e-19 70.0 0.1 2.0 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SNF2_N PF00176.23 CRK37378.1 - 3.1e-109 364.9 5.8 1.1e-32 113.2 0.1 4.9 4 0 0 4 4 4 4 SNF2 family N-terminal domain Helicase_C PF00271.31 CRK37378.1 - 1.7e-41 141.0 0.4 2.9e-18 66.2 0.0 4.8 5 0 0 5 5 5 2 Helicase conserved C-terminal domain HSA PF07529.13 CRK37378.1 - 3.1e-31 107.5 36.0 2e-15 56.9 11.9 4.4 4 0 0 4 4 4 2 HSA Bromodomain PF00439.25 CRK37378.1 - 6.6e-20 71.0 0.1 2e-19 69.5 0.1 1.8 1 0 0 1 1 1 1 Bromodomain SnAC PF14619.6 CRK37378.1 - 4.3e-15 56.1 3.6 4.8e-14 52.7 1.9 6.1 7 0 0 7 7 4 2 Snf2-ATP coupling, chromatin remodelling complex QLQ PF08880.11 CRK37378.1 - 3.6e-14 52.2 14.5 7.2e-12 44.9 2.7 3.4 3 0 0 3 3 3 2 QLQ HDA2-3 PF11496.8 CRK37378.1 - 5.1e-10 39.0 0.0 0.0027 16.9 0.0 3.7 2 2 0 2 2 2 2 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 CRK37378.1 - 4.3e-06 26.9 0.0 0.00015 21.8 0.0 5.7 6 0 0 6 6 6 2 Type III restriction enzyme, res subunit DUF1289 PF06945.13 CRK37378.1 - 0.055 13.3 0.7 13 5.7 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) TERF2_RBM PF16772.5 CRK37378.1 - 0.085 12.3 1.1 8.9 5.8 0.0 3.4 3 0 0 3 3 3 0 Telomeric repeat-binding factor 2 Rap1-binding motif AbiEi_2 PF09952.9 CRK37378.1 - 0.18 12.0 2.9 45 4.3 0.0 4.3 4 2 2 6 6 5 0 Transcriptional regulator, AbiEi antitoxin, Type IV TA system Poxvirus PF06227.12 CRK37378.1 - 0.25 11.1 3.7 15 5.3 0.0 3.3 4 0 0 4 4 4 0 dsDNA Poxvirus RBR PF17208.3 CRK37378.1 - 0.6 10.9 6.1 1.2 9.9 4.4 2.5 1 1 0 1 1 1 0 RNA binding Region BCNT PF07572.12 CRK37380.1 - 3.2e-23 81.6 2.1 7.3e-23 80.4 2.1 1.6 1 0 0 1 1 1 1 Bucentaur or craniofacial development DSBA PF01323.20 CRK37381.1 - 2.7e-14 53.4 0.0 4.7e-14 52.6 0.0 1.4 1 1 0 1 1 1 1 DSBA-like thioredoxin domain adh_short PF00106.25 CRK37382.1 - 3.1e-28 98.6 0.1 7.3e-19 68.0 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CRK37382.1 - 5.4e-22 78.5 0.3 3.3e-17 62.8 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK37382.1 - 2.4e-05 24.3 0.0 4.6e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 CRK37382.1 - 0.082 12.3 0.0 0.34 10.2 0.0 1.9 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 CRK37382.1 - 0.098 12.5 2.4 1.9 8.3 0.6 2.8 2 1 0 2 2 2 0 NAD(P)H-binding Epimerase PF01370.21 CRK37382.1 - 0.12 11.9 0.0 0.28 10.6 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Dus PF01207.17 CRK37383.1 - 5.4e-28 98.0 0.0 7.9e-23 81.0 0.0 2.4 1 1 1 2 2 2 2 Dihydrouridine synthase (Dus) HTH_16 PF12645.7 CRK37383.1 - 0.028 14.5 0.7 17 5.6 0.1 3.1 3 0 0 3 3 3 0 Helix-turn-helix domain DUF4863 PF16155.5 CRK37383.1 - 0.1 12.5 0.1 13 5.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4863) Carb_anhydrase PF00194.21 CRK37385.1 - 2.3e-34 119.1 0.1 4.1e-34 118.3 0.1 1.3 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase CA_like PF10563.9 CRK37385.1 - 0.01 15.7 0.3 4.2 7.2 0.2 2.3 1 1 1 2 2 2 0 Putative carbonic anhydrase Nuc_N PF14448.6 CRK37385.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Nuclease N terminal Auxin_repressed PF05564.12 CRK37386.1 - 0.011 16.4 0.5 0.013 16.2 0.5 1.2 1 0 0 1 1 1 0 Dormancy/auxin associated protein AAA PF00004.29 CRK37387.1 - 2.7e-48 163.7 0.0 3e-42 144.2 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CRK37387.1 - 1.6e-08 34.2 0.0 4e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 CRK37387.1 - 6.1e-08 33.2 0.5 0.00045 20.7 0.3 3.4 2 1 0 2 2 2 2 AAA ATPase domain IstB_IS21 PF01695.17 CRK37387.1 - 3.6e-07 30.1 0.0 1.1e-05 25.2 0.0 2.4 2 1 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.14 CRK37387.1 - 1.9e-06 28.1 0.0 4.8e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 CRK37387.1 - 0.00036 20.8 0.2 0.026 14.8 0.2 3.2 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 CRK37387.1 - 0.00077 19.5 0.1 0.0063 16.5 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 CRK37387.1 - 0.0025 18.2 0.0 0.016 15.6 0.0 2.2 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.6 CRK37387.1 - 0.0066 16.6 1.3 0.03 14.5 0.0 2.7 3 0 0 3 3 3 1 AAA domain TIP49 PF06068.13 CRK37387.1 - 0.0083 15.4 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_14 PF13173.6 CRK37387.1 - 0.011 15.7 0.0 0.034 14.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CRK37387.1 - 0.014 16.0 0.1 0.082 13.4 0.0 2.4 3 0 0 3 3 1 0 ABC transporter RuvB_N PF05496.12 CRK37387.1 - 0.015 15.1 0.0 0.035 13.9 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 CRK37387.1 - 0.021 15.4 0.0 0.11 13.1 0.0 2.3 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.6 CRK37387.1 - 0.034 13.7 0.0 0.092 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 CRK37387.1 - 0.042 13.2 0.1 0.1 12.0 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 CRK37387.1 - 0.056 13.2 0.0 1.7 8.4 0.0 2.8 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_7 PF12775.7 CRK37387.1 - 0.056 13.0 0.0 0.13 11.8 0.0 1.5 2 0 0 2 2 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 CRK37387.1 - 0.06 13.6 0.0 0.18 12.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 CRK37387.1 - 0.089 11.9 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_3 PF07726.11 CRK37387.1 - 0.09 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 CRK37387.1 - 0.12 12.2 0.2 0.39 10.6 0.1 2.0 2 1 0 2 2 1 0 NACHT domain Torsin PF06309.11 CRK37387.1 - 0.24 11.5 0.1 0.72 10.0 0.0 1.7 2 0 0 2 2 2 0 Torsin AAA_11 PF13086.6 CRK37387.1 - 0.36 10.6 0.0 0.36 10.6 0.0 3.3 2 1 0 2 2 1 0 AAA domain 2-oxoacid_dh PF00198.23 CRK37388.1 - 6.1e-80 268.0 0.1 9.2e-80 267.4 0.1 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 CRK37388.1 - 1.8e-18 66.1 2.2 3.6e-18 65.2 2.2 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 CRK37388.1 - 0.00041 20.1 0.6 0.34 10.8 0.1 2.4 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.6 CRK37388.1 - 0.002 18.8 0.5 0.11 13.2 0.3 2.4 1 1 0 1 1 1 1 HlyD family secretion protein RnfC_N PF13375.6 CRK37388.1 - 0.03 14.3 1.3 1 9.4 0.0 3.1 1 1 2 3 3 3 0 RnfC Barrel sandwich hybrid domain GCV_H PF01597.19 CRK37388.1 - 0.037 13.9 0.3 0.081 12.8 0.3 1.6 1 0 0 1 1 1 0 Glycine cleavage H-protein Ndc1_Nup PF09531.10 CRK37388.1 - 0.59 8.8 6.6 0.74 8.4 6.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 CRK37388.1 - 0.7 8.6 4.1 1 8.1 4.1 1.1 1 0 0 1 1 1 0 Presenilin FAM76 PF16046.5 CRK37388.1 - 0.82 9.0 4.2 15 4.9 2.4 2.1 2 0 0 2 2 2 0 FAM76 protein DUF3614 PF12267.8 CRK37388.1 - 1 9.8 6.1 1.5 9.3 0.0 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF3614) Apt1 PF10351.9 CRK37388.1 - 4.2 6.1 8.2 5.8 5.7 8.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain XRN_M PF17846.1 CRK37389.1 - 1.2e-138 462.9 0.0 6.8e-138 460.3 0.0 2.0 1 1 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 CRK37389.1 - 1.2e-97 326.1 0.0 2.1e-97 325.3 0.0 1.4 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus RasGAP PF00616.19 CRK37389.1 - 4.2e-14 52.7 0.5 4e-11 43.0 0.5 2.5 1 1 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 CRK37389.1 - 1.1e-10 41.8 0.2 2.9e-10 40.4 0.2 1.7 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain zf-CCHC_2 PF13696.6 CRK37389.1 - 0.45 10.4 3.3 1.1 9.1 3.3 1.7 1 0 0 1 1 1 0 Zinc knuckle Uso1_p115_head PF04869.14 CRK37390.1 - 4.1e-110 367.8 0.0 9.2e-110 366.6 0.0 1.6 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 CRK37390.1 - 6.2e-14 52.4 31.2 6.2e-14 52.4 31.2 3.9 1 1 2 3 3 3 1 Uso1 / p115 like vesicle tethering protein, C terminal region Rav1p_C PF12234.8 CRK37391.1 - 3.9e-278 924.2 0.0 5e-278 923.8 0.0 1.1 1 0 0 1 1 1 1 RAVE protein 1 C terminal OPT PF03169.15 CRK37391.1 - 2.1e-116 390.0 11.0 2.9e-116 389.6 11.0 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein MadL PF03817.13 CRK37391.1 - 5.6 7.0 9.3 2.9 8.0 6.5 2.0 2 0 0 2 2 2 0 Malonate transporter MadL subunit Sfi1 PF08457.10 CRK37392.1 - 2.3e-24 85.9 60.3 1.1e-14 53.9 48.7 2.9 1 1 1 2 2 2 2 Sfi1 spindle body protein DUF4186 PF13811.6 CRK37392.1 - 0.59 10.2 6.3 1.4 9.0 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4186) CX9C PF16860.5 CRK37392.1 - 1.3 9.1 5.3 5.7 7.0 2.3 2.4 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CX9C PF16860.5 CRK37393.1 - 0.00013 21.9 0.6 0.00017 21.5 0.6 1.2 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 CRK37393.1 - 0.019 15.1 1.7 0.068 13.3 1.8 1.7 1 1 1 2 2 2 0 CHCH domain Rota_NSP4 PF01452.16 CRK37393.1 - 0.021 14.5 0.4 0.025 14.3 0.4 1.0 1 0 0 1 1 1 0 Rotavirus non structural protein NDUF_B7 PF05676.13 CRK37393.1 - 0.031 14.0 1.1 1.9 8.3 0.0 2.1 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Pkinase PF00069.25 CRK37395.1 - 3.7e-16 59.3 0.0 9.2e-12 44.9 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain SWIB PF02201.18 CRK37395.1 - 5.3e-16 58.3 0.0 1.8e-15 56.6 0.0 1.9 2 0 0 2 2 2 1 SWIB/MDM2 domain Pkinase_Tyr PF07714.17 CRK37395.1 - 0.00011 21.6 0.0 0.00058 19.2 0.0 2.0 1 1 1 2 2 2 1 Protein tyrosine kinase XPG_I PF00867.18 CRK37400.1 - 3.7e-26 91.3 0.0 6.1e-26 90.6 0.0 1.4 1 0 0 1 1 1 1 XPG I-region GEN1_C PF18380.1 CRK37400.1 - 5.9e-19 68.9 0.0 1e-18 68.2 0.0 1.3 1 0 0 1 1 1 1 Holliday junction resolvase Gen1 C-terminal domain XPG_N PF00752.17 CRK37400.1 - 4.2e-08 33.6 0.0 8.9e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 CRK37400.1 - 0.063 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 XPG domain containing Actin PF00022.19 CRK37401.1 - 6.5e-20 71.1 0.0 2.1e-11 43.1 0.0 3.4 3 1 0 3 3 3 3 Actin tRNA-synt_2b PF00587.25 CRK37403.1 - 3.8e-19 69.3 0.0 1e-18 68.0 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 CRK37403.1 - 1.5e-12 47.7 1.2 3.2e-12 46.6 1.2 1.6 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Mito_carr PF00153.27 CRK37404.1 - 5.7e-24 83.9 0.5 7.5e-11 41.8 0.0 3.6 3 0 0 3 3 3 3 Mitochondrial carrier protein Tup_N PF08581.10 CRK37404.1 - 0.00093 19.4 1.3 0.00093 19.4 1.3 7.9 5 2 0 7 7 7 1 Tup N-terminal Apolipoprotein PF01442.18 CRK37404.1 - 0.0013 18.7 10.7 0.0013 18.7 10.7 8.7 4 2 2 6 6 6 2 Apolipoprotein A1/A4/E domain HALZ PF02183.18 CRK37404.1 - 0.0066 16.6 1.8 0.85 9.9 1.3 3.1 2 0 0 2 2 2 1 Homeobox associated leucine zipper EF-hand_4 PF12763.7 CRK37407.1 - 1.8e-29 101.7 0.0 2.6e-11 43.4 0.0 3.3 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 CRK37407.1 - 3.6e-10 40.1 0.0 0.00072 20.0 0.0 4.3 4 0 0 4 4 4 1 EF-hand domain pair UBA PF00627.31 CRK37407.1 - 2.4e-06 27.3 0.1 5.1e-06 26.3 0.1 1.5 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_1 PF00036.32 CRK37407.1 - 3.3e-06 26.2 0.0 4.6 7.0 0.0 5.2 5 0 0 5 5 5 1 EF hand EF-hand_6 PF13405.6 CRK37407.1 - 9.1e-06 25.2 0.0 0.76 9.9 0.0 4.6 5 0 0 5 5 5 1 EF-hand domain Spc7 PF08317.11 CRK37407.1 - 0.03 13.2 4.6 0.042 12.7 4.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Uso1_p115_C PF04871.13 CRK37407.1 - 0.039 14.3 6.1 0.067 13.6 6.1 1.3 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF4201 PF13870.6 CRK37407.1 - 0.042 13.6 1.5 0.066 13.0 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) DHR10 PF18595.1 CRK37407.1 - 0.082 13.0 3.7 0.13 12.3 3.7 1.2 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain EF-hand_8 PF13833.6 CRK37407.1 - 0.1 12.4 0.0 13 5.7 0.0 3.4 4 0 0 4 4 4 0 EF-hand domain pair DUF4407 PF14362.6 CRK37407.1 - 0.11 11.8 0.3 0.18 11.1 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LPP PF04728.13 CRK37407.1 - 0.13 12.7 2.6 0.26 11.7 2.6 1.6 1 0 0 1 1 1 0 Lipoprotein leucine-zipper TolA_bind_tri PF16331.5 CRK37407.1 - 0.14 12.3 9.4 0.047 13.8 6.0 1.9 2 0 0 2 2 2 0 TolA binding protein trimerisation Seryl_tRNA_N PF02403.22 CRK37407.1 - 0.14 12.4 4.5 0.26 11.5 4.5 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain COG2 PF06148.11 CRK37407.1 - 0.26 11.4 2.3 0.44 10.6 2.3 1.3 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Spc24 PF08286.11 CRK37407.1 - 0.7 10.2 2.7 1.3 9.3 2.7 1.4 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 APG6_N PF17675.1 CRK37407.1 - 0.82 10.2 4.5 1.6 9.2 4.5 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region Pga1 PF10333.9 CRK37411.1 - 3e-05 23.9 0.0 0.0016 18.3 0.0 2.2 2 1 0 2 2 2 2 GPI-Mannosyltransferase II co-activator bact-PGI_C PF10432.9 CRK37411.1 - 0.18 11.8 0.4 1 9.4 0.1 2.0 2 0 0 2 2 2 0 Bacterial phospho-glucose isomerase C-terminal SIS domain WW PF00397.26 CRK37413.1 - 3e-07 30.4 0.7 7.4e-07 29.2 0.7 1.7 1 0 0 1 1 1 1 WW domain Pga1 PF10333.9 CRK37417.1 - 2.4e-05 24.2 0.0 0.00041 20.3 0.0 2.1 2 0 0 2 2 2 2 GPI-Mannosyltransferase II co-activator LsmAD PF06741.13 CRK37418.1 - 3e-29 101.4 2.0 8e-29 100.0 2.0 1.8 1 0 0 1 1 1 1 LsmAD domain WW PF00397.26 CRK37418.1 - 4.1e-06 26.8 0.5 8.6e-06 25.7 0.5 1.5 1 0 0 1 1 1 1 WW domain DUF3383 PF11863.8 CRK37418.1 - 0.0021 17.2 0.9 0.0029 16.7 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3383) RNA_pol_Rpc82 PF05645.13 CRK37419.1 - 6.5e-51 173.6 0.0 3.8e-47 161.2 0.0 3.5 4 0 0 4 4 4 2 RNA polymerase III subunit RPC82 HTH_9 PF08221.11 CRK37419.1 - 8.2e-18 64.3 0.2 1.2e-15 57.4 0.0 3.6 4 0 0 4 4 4 1 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 CRK37419.1 - 4.1e-06 26.6 0.0 0.21 11.4 0.0 3.3 3 1 0 3 3 3 2 TFIIE alpha subunit SNF PF00209.18 CRK37420.1 - 3.1e-86 290.2 25.1 2e-84 284.2 25.0 2.2 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family DUF2518 PF10726.9 CRK37420.1 - 6.6 6.4 6.2 0.84 9.3 1.1 2.2 2 0 0 2 2 2 0 Protein of function (DUF2518) Sec6 PF06046.13 CRK37421.1 - 1.4e-167 558.5 9.0 2.2e-167 557.9 9.0 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec6 Pirin PF02678.16 CRK37421.1 - 1.4e-29 102.2 0.0 3.2e-29 101.1 0.0 1.7 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 CRK37421.1 - 1.6e-27 95.8 0.0 2.9e-26 91.9 0.0 2.4 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 CRK37421.1 - 3e-07 30.0 0.6 0.00018 21.2 0.4 2.4 2 0 0 2 2 2 2 Cupin domain Vps53_N PF04100.12 CRK37421.1 - 3.1e-05 23.1 0.7 3.1e-05 23.1 0.7 1.8 2 0 0 2 2 2 1 Vps53-like, N-terminal OmdA PF13376.6 CRK37421.1 - 0.016 15.2 2.0 0.43 10.6 0.0 3.4 3 0 0 3 3 3 0 Bacteriocin-protection, YdeI or OmpD-Associated DUF755 PF05501.11 CRK37421.1 - 0.077 13.3 0.2 0.19 12.0 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Cupin_3 PF05899.12 CRK37421.1 - 0.077 12.7 0.1 1.3 8.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Vault_2 PF17794.1 CRK37422.1 - 0.076 13.4 0.0 0.43 11.0 0.0 2.0 2 0 0 2 2 2 0 Major Vault Protein repeat domain bZIP_2 PF07716.15 CRK37423.1 - 1.3e-11 44.3 10.0 3.9e-11 42.8 10.0 1.9 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 CRK37423.1 - 0.0067 16.5 8.6 0.016 15.3 8.6 1.6 1 0 0 1 1 1 1 bZIP transcription factor TatD_DNase PF01026.21 CRK37424.1 - 1.2e-46 159.2 0.0 1.9e-46 158.5 0.0 1.3 1 1 0 1 1 1 1 TatD related DNase Ribonuc_red_lgC PF02867.15 CRK37426.1 - 1.4e-189 631.1 0.0 2e-189 630.5 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 CRK37426.1 - 8.3e-23 80.2 0.0 5.1e-22 77.7 0.0 2.2 2 0 0 2 2 2 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 CRK37426.1 - 5.9e-17 62.0 0.0 1.2e-16 61.0 0.0 1.6 1 0 0 1 1 1 1 ATP cone domain CFEM PF05730.11 CRK37427.1 - 4.9e-09 36.1 6.4 9.4e-09 35.2 6.4 1.5 1 0 0 1 1 1 1 CFEM domain zf-HIT PF04438.16 CRK37428.1 - 2.9e-10 39.8 7.8 4.3e-10 39.3 7.8 1.2 1 0 0 1 1 1 1 HIT zinc finger BUD22 PF09073.10 CRK37428.1 - 0.16 11.3 26.4 0.7 9.2 0.3 2.2 2 0 0 2 2 2 0 BUD22 zf-MYND PF01753.18 CRK37428.1 - 3.1 8.0 8.7 5.4 7.2 8.7 1.4 1 0 0 1 1 1 0 MYND finger DENN PF02141.21 CRK37429.1 - 6.7e-28 97.9 0.0 1.1e-27 97.2 0.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain Elongin_A PF06881.11 CRK37429.1 - 0.011 16.3 6.2 0.011 16.3 6.2 2.1 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A BRE1 PF08647.11 CRK37429.1 - 0.86 9.7 16.0 0.84 9.7 7.1 2.5 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase LPP PF04728.13 CRK37429.1 - 2.4 8.6 5.5 33 5.0 0.2 3.5 3 0 0 3 3 3 0 Lipoprotein leucine-zipper GAS PF13851.6 CRK37429.1 - 3.3 7.0 21.6 12 5.2 5.5 2.9 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding DUF3456 PF11938.8 CRK37429.1 - 3.8 8.0 6.6 0.64 10.5 0.2 2.4 1 1 1 2 2 2 0 TLR4 regulator and MIR-interacting MSAP DUF2570 PF10828.8 CRK37429.1 - 4.2 7.2 11.4 2.3 8.1 6.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) DENN PF02141.21 CRK37430.1 - 1.3e-47 162.2 0.0 4.8e-39 134.2 0.1 2.4 2 0 0 2 2 2 2 DENN (AEX-3) domain uDENN PF03456.18 CRK37430.1 - 1.8e-05 25.4 0.1 0.00012 22.8 0.0 2.5 2 0 0 2 2 2 1 uDENN domain Elongin_A PF06881.11 CRK37430.1 - 0.0057 17.2 6.1 0.025 15.1 6.1 2.1 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A BRE1 PF08647.11 CRK37430.1 - 0.98 9.5 15.3 0.77 9.9 7.0 2.6 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase GAS PF13851.6 CRK37430.1 - 3.3 7.0 20.4 5.5 6.3 7.7 2.8 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding DUF2570 PF10828.8 CRK37430.1 - 8.7 6.2 11.1 3.7 7.4 6.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) zf-HIT PF04438.16 CRK37431.1 - 4.4e-10 39.2 8.0 6.5e-10 38.7 8.0 1.2 1 0 0 1 1 1 1 HIT zinc finger BUD22 PF09073.10 CRK37431.1 - 1.4 8.2 20.6 2 7.7 0.7 2.2 2 0 0 2 2 2 0 BUD22 CFEM PF05730.11 CRK37432.1 - 4.9e-09 36.1 6.4 9.1e-09 35.3 6.4 1.4 1 0 0 1 1 1 1 CFEM domain Ribonuc_red_lgC PF02867.15 CRK37433.1 - 2.8e-105 352.8 0.4 5.2e-98 328.9 0.0 2.3 2 0 0 2 2 2 2 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 CRK37433.1 - 6.5e-23 80.5 0.0 4.9e-22 77.7 0.0 2.3 2 0 0 2 2 2 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 CRK37433.1 - 4.1e-17 62.5 0.0 8.7e-17 61.5 0.0 1.6 1 0 0 1 1 1 1 ATP cone domain TatD_DNase PF01026.21 CRK37434.1 - 7e-46 156.7 0.0 1.2e-45 155.9 0.0 1.4 1 1 0 1 1 1 1 TatD related DNase CENP-N PF05238.13 CRK37435.1 - 7.2e-184 611.9 0.0 2.4e-117 392.7 0.0 2.0 1 1 1 2 2 2 2 Kinetochore protein CHL4 like Cnl2_NKP2 PF09447.10 CRK37435.1 - 4.8e-05 23.4 0.2 0.58 10.4 0.0 2.5 2 0 0 2 2 2 2 Cnl2/NKP2 family protein H-kinase_dim PF02895.14 CRK37435.1 - 0.021 15.2 0.1 13 6.3 0.0 2.5 2 0 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain VirE3 PF06661.11 CRK37435.1 - 0.051 12.8 0.1 11 5.2 0.0 2.2 2 0 0 2 2 2 0 VirE3 CENP-N PF05238.13 CRK37436.1 - 2.8e-39 135.6 0.1 3.2e-39 135.4 0.1 1.0 1 0 0 1 1 1 1 Kinetochore protein CHL4 like bZIP_2 PF07716.15 CRK37437.1 - 1.3e-11 44.4 10.0 2e-11 43.8 10.0 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 CRK37437.1 - 0.0046 17.0 8.6 0.0082 16.2 8.6 1.4 1 0 0 1 1 1 1 bZIP transcription factor TSC22 PF01166.18 CRK37437.1 - 0.12 12.7 0.3 0.24 11.8 0.3 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family APC_u14 PF16635.5 CRK37437.1 - 5.5 7.6 8.9 1.2 9.7 3.7 2.4 2 1 0 2 2 2 0 Unstructured region on APC between SAMP and APC_crr Aminotran_1_2 PF00155.21 CRK37438.1 - 1.1e-32 113.6 0.0 1.2e-32 113.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_1_2 PF00155.21 CRK37439.1 - 1.1e-32 113.6 0.0 1.2e-32 113.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II VWA PF00092.28 CRK37440.1 - 5.5e-06 26.8 0.0 5.2e-05 23.6 0.0 2.1 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CRK37440.1 - 0.00057 20.5 0.0 0.0018 18.9 0.0 1.9 1 1 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.9 CRK37440.1 - 0.17 11.9 0.0 0.53 10.4 0.0 1.7 1 1 0 1 1 1 0 vWA found in TerF C terminus Pro_isomerase PF00160.21 CRK37442.1 - 7.8e-44 149.7 0.0 8.9e-44 149.5 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD NmrA PF05368.13 CRK37443.1 - 7.8e-56 189.2 0.0 9.5e-56 189.0 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 CRK37443.1 - 1.1e-15 58.0 0.7 1.5e-15 57.6 0.3 1.4 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 CRK37443.1 - 0.00033 20.2 0.1 0.00063 19.3 0.1 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CRK37443.1 - 0.0021 17.1 0.0 0.003 16.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 CRK37443.1 - 0.0055 17.0 0.1 0.0086 16.3 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain adh_short_C2 PF13561.6 CRK37443.1 - 0.088 12.4 0.3 0.15 11.6 0.3 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase TrkA_N PF02254.18 CRK37443.1 - 0.1 12.9 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain adh_short_C2 PF13561.6 CRK37444.1 - 4.8e-56 189.9 7.5 5.7e-56 189.7 7.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRK37444.1 - 1.8e-45 154.8 3.8 2.2e-45 154.5 3.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CRK37444.1 - 6.9e-10 39.1 3.2 1.7e-09 37.8 3.2 1.6 1 1 0 1 1 1 1 KR domain EF-hand_6 PF13405.6 CRK37445.1 - 6.3e-08 32.0 0.1 0.002 17.9 0.1 2.6 2 1 1 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 CRK37445.1 - 0.00018 21.9 0.1 0.00026 21.4 0.1 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 CRK37445.1 - 0.002 17.6 0.1 0.1 12.2 0.0 2.3 2 0 0 2 2 2 1 EF hand EF-hand_1 PF00036.32 CRK37445.1 - 0.0038 16.7 0.0 0.63 9.7 0.0 2.6 3 0 0 3 3 3 1 EF hand PepSY_2 PF13670.6 CRK37445.1 - 0.95 9.5 5.9 2.2 8.3 5.9 1.7 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain adh_short PF00106.25 CRK37446.1 - 2.5e-33 115.2 1.8 3.2e-33 114.8 1.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK37446.1 - 7.6e-28 97.6 4.8 7.7e-28 97.6 3.8 1.4 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK37446.1 - 4.5e-09 36.5 2.1 4.5e-09 36.5 2.1 1.9 2 1 0 2 2 2 1 KR domain adh_short PF00106.25 CRK37447.1 - 1.2e-22 80.3 0.0 6e-16 58.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CRK37447.1 - 7.3e-16 58.4 0.0 6e-15 55.4 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 CRK37447.1 - 5.2e-05 22.8 0.0 7.7e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CRK37447.1 - 0.00016 21.2 0.0 0.00031 20.3 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.10 CRK37447.1 - 0.0032 17.4 0.0 0.0052 16.7 0.0 1.3 1 0 0 1 1 1 1 KR domain RCR PF12273.8 CRK37448.1 - 3.6e-05 24.4 1.0 8.1e-05 23.3 1.0 1.6 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red DUF4448 PF14610.6 CRK37448.1 - 0.021 14.6 0.0 0.034 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Rax2 PF12768.7 CRK37448.1 - 0.22 10.9 0.0 0.35 10.3 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity NmrA PF05368.13 CRK37449.1 - 1.4e-52 178.6 0.2 6.6e-34 117.5 0.8 2.1 2 0 0 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.6 CRK37449.1 - 1.5e-13 51.1 0.3 2.9e-13 50.1 0.3 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 CRK37449.1 - 0.0019 17.7 0.1 0.0039 16.7 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CRK37449.1 - 0.0069 15.4 0.0 0.0099 14.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 CRK37449.1 - 0.032 14.5 0.1 0.061 13.6 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain GP17 PF17420.2 CRK37449.1 - 0.27 11.4 1.1 19 5.5 0.2 2.4 2 0 0 2 2 2 0 Superinfection exclusion gene product 17 ORC6 PF05460.13 CRK37450.1 - 9.3e-36 123.8 1.3 4e-34 118.5 0.2 2.1 2 0 0 2 2 2 2 Origin recognition complex subunit 6 (ORC6) TFIIB_C_1 PF18542.1 CRK37450.1 - 0.05 13.6 0.0 0.31 11.1 0.0 2.1 2 0 0 2 2 2 0 Transcription factor IIB C-terminal module 1 EF-hand_6 PF13405.6 CRK37451.1 - 8.2e-08 31.6 1.4 0.0029 17.4 0.1 3.2 3 1 1 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 CRK37451.1 - 7.2e-05 23.2 0.5 0.00014 22.3 0.1 1.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 CRK37451.1 - 0.00051 19.4 0.1 0.021 14.3 0.0 2.4 2 0 0 2 2 2 1 EF hand EF-hand_1 PF00036.32 CRK37451.1 - 0.0018 17.7 0.1 0.21 11.2 0.0 2.6 3 0 0 3 3 3 1 EF hand Rpr2 PF04032.16 CRK37452.1 - 8e-15 54.9 0.3 8e-15 54.9 0.3 1.9 2 0 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF3807 PF12720.7 CRK37452.1 - 7.9 6.7 8.3 5.4 7.2 6.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) zf-ZPR1 PF03367.13 CRK37453.1 - 7e-18 65.0 2.8 7e-18 65.0 2.8 1.4 2 0 0 2 2 2 1 ZPR1 zinc-finger domain Paired_CXXCH_1 PF09699.10 CRK37453.1 - 0.037 13.8 0.2 0.037 13.8 0.2 1.5 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) zf-ZPR1 PF03367.13 CRK37454.1 - 1.3e-91 304.6 0.5 5.9e-54 182.2 0.0 2.2 2 0 0 2 2 2 2 ZPR1 zinc-finger domain zinc-ribbons_6 PF07191.12 CRK37454.1 - 1.1 9.3 4.2 4.6 7.3 0.6 2.3 2 0 0 2 2 2 0 zinc-ribbons Peptidase_M41 PF01434.18 CRK37456.1 - 2.3e-57 193.9 0.7 4e-57 193.2 0.7 1.4 1 0 0 1 1 1 1 Peptidase family M41 Epimerase PF01370.21 CRK37456.1 - 1.7e-29 103.0 0.0 8.5e-14 51.6 0.0 4.6 2 1 2 4 4 4 4 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CRK37456.1 - 2.3e-18 66.2 0.0 7.6e-11 41.5 0.0 3.8 2 1 2 4 4 4 3 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 CRK37456.1 - 3.3e-17 62.5 0.0 6.8e-09 35.3 0.0 4.3 2 1 2 4 4 4 3 Male sterility protein AAA_lid_3 PF17862.1 CRK37456.1 - 5.5e-12 45.3 0.1 6.4e-10 38.7 0.1 3.4 3 0 0 3 3 3 1 AAA+ lid domain Polysacc_synt_2 PF02719.15 CRK37456.1 - 2.1e-10 40.2 0.0 1.6e-07 30.7 0.0 2.4 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 CRK37456.1 - 2.5e-10 40.5 5.2 2.1e-08 34.3 0.2 3.6 3 0 0 3 3 3 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 CRK37456.1 - 1.4e-09 37.8 0.2 4.1e-08 33.0 0.0 3.4 4 1 0 4 4 4 1 GDP-mannose 4,6 dehydratase KR PF08659.10 CRK37456.1 - 1.3e-06 28.4 0.2 3.1e-05 23.9 0.0 2.9 3 0 0 3 3 3 1 KR domain AAA PF00004.29 CRK37456.1 - 3.9e-05 24.1 0.1 0.00014 22.2 0.0 2.1 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) adh_short PF00106.25 CRK37456.1 - 6.8e-05 22.4 0.0 0.00031 20.3 0.0 2.2 1 0 0 1 1 1 1 short chain dehydrogenase Hydant_A_N PF05378.13 CRK37456.1 - 0.11 12.2 0.2 8.7 6.0 0.0 3.3 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase N-terminal region GPHR_N PF12537.8 CRK37456.1 - 2.3 8.3 12.0 50 4.1 0.1 5.1 5 0 0 5 5 5 0 The Golgi pH Regulator (GPHR) Family N-terminal zf-ZPR1 PF03367.13 CRK37457.1 - 5.7e-34 117.3 0.0 9.8e-34 116.5 0.0 1.3 1 0 0 1 1 1 1 ZPR1 zinc-finger domain zf-C2H2 PF00096.26 CRK37458.1 - 4.5e-20 70.9 30.2 1.2e-05 25.5 0.1 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CRK37458.1 - 1.1e-17 63.6 27.9 2.4e-06 27.7 0.6 5.3 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 CRK37458.1 - 2.9e-09 37.0 27.2 0.015 16.1 1.2 5.0 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_11 PF16622.5 CRK37458.1 - 0.016 14.9 2.0 0.016 14.9 2.0 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-met PF12874.7 CRK37458.1 - 0.04 14.3 1.0 0.04 14.3 1.0 5.0 6 0 0 6 6 6 0 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 CRK37458.1 - 0.045 14.1 13.4 1 9.7 6.3 3.5 2 1 1 3 3 3 0 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 CRK37458.1 - 0.064 13.6 11.0 0.55 10.6 0.5 4.1 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding GDPD PF03009.17 CRK37460.1 - 3.9e-41 141.5 0.0 4.7e-41 141.2 0.0 1.0 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 CRK37462.1 - 4.8e-38 129.6 1.0 5.8e-17 62.1 0.1 4.6 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CRK37462.1 - 5.9e-23 80.9 2.9 7e-09 36.1 0.1 5.8 4 2 0 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 CRK37462.1 - 5.3e-20 71.2 0.3 6.8e-07 29.4 0.0 5.6 3 1 2 5 5 5 3 Ankyrin repeats (many copies) SPX PF03105.19 CRK37462.1 - 1.1e-18 68.4 8.3 7e-11 42.7 0.1 4.0 3 1 1 4 4 4 3 SPX domain Ank_3 PF13606.6 CRK37462.1 - 1.4e-16 58.9 3.2 0.0011 19.2 0.0 8.3 9 0 0 9 9 9 3 Ankyrin repeat Ank PF00023.30 CRK37462.1 - 2.1e-14 53.2 5.6 0.0016 18.8 0.0 6.7 7 0 0 7 7 7 3 Ankyrin repeat GDPD PF03009.17 CRK37462.1 - 3.2e-13 50.0 0.0 8.2e-13 48.7 0.0 1.7 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DinB_2 PF12867.7 CRK37463.1 - 0.35 11.4 3.1 5.7 7.5 2.4 2.6 1 1 1 2 2 2 0 DinB superfamily DUF866 PF05907.13 CRK37464.1 - 4.7e-65 218.2 1.2 5.2e-65 218.1 1.2 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Zn_ribbon_SprT PF17283.2 CRK37464.1 - 0.034 14.0 1.5 3.2 7.7 0.0 2.2 2 0 0 2 2 2 0 SprT-like zinc ribbon domain HalOD2 PF18547.1 CRK37464.1 - 0.093 12.7 0.9 1.2 9.1 0.1 2.2 2 0 0 2 2 2 0 Halobacterial output domain 2 DUF4379 PF14311.6 CRK37464.1 - 0.62 10.5 6.1 0.15 12.4 1.1 2.3 1 1 1 2 2 2 0 Probable Zinc-ribbon domain Metallophos PF00149.28 CRK37465.1 - 6.1e-32 111.8 0.0 1.9e-27 97.1 0.0 2.4 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 CRK37465.1 - 0.049 13.3 0.0 0.082 12.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Neugrin PF06413.11 CRK37465.1 - 0.082 12.9 0.3 0.2 11.7 0.3 1.6 1 0 0 1 1 1 0 Neugrin DUF866 PF05907.13 CRK37466.1 - 5e-65 218.2 0.8 5.5e-65 218.0 0.8 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Zn_ribbon_SprT PF17283.2 CRK37466.1 - 0.034 14.0 1.5 3.2 7.7 0.0 2.2 2 0 0 2 2 2 0 SprT-like zinc ribbon domain HalOD2 PF18547.1 CRK37466.1 - 0.099 12.6 1.1 1.2 9.1 0.1 2.2 2 0 0 2 2 2 0 Halobacterial output domain 2 DUF4379 PF14311.6 CRK37466.1 - 0.46 10.9 5.4 0.16 12.4 1.1 2.3 1 1 1 2 2 2 0 Probable Zinc-ribbon domain Smg4_UPF3 PF03467.15 CRK37468.1 - 1.1e-43 149.2 0.0 1.1e-43 149.2 0.0 3.4 3 1 0 3 3 3 1 Smg-4/UPF3 family RRM_1 PF00076.22 CRK37468.1 - 1.6e-06 27.8 0.3 0.00044 20.0 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HTH_18 PF12833.7 CRK37468.1 - 0.046 14.0 1.4 0.3 11.4 0.2 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain TRF PF08558.10 CRK37470.1 - 3.1e-18 66.3 0.3 6.2e-18 65.3 0.3 1.5 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.31 CRK37470.1 - 9.2e-05 22.6 0.0 0.00023 21.3 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF641 PF04859.12 CRK37470.1 - 0.017 15.4 6.7 4.4 7.7 0.2 4.1 3 1 1 4 4 4 0 Plant protein of unknown function (DUF641) IFT20 PF14931.6 CRK37470.1 - 0.034 14.3 2.1 4.7 7.4 0.1 2.8 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 RRF_GI PF12614.8 CRK37470.1 - 0.046 13.9 6.0 3.2 7.9 0.4 2.7 2 0 0 2 2 2 0 Ribosome recycling factor AAA_13 PF13166.6 CRK37470.1 - 0.047 12.3 7.5 0.67 8.5 0.1 3.1 3 0 0 3 3 3 0 AAA domain CENP-F_leu_zip PF10473.9 CRK37470.1 - 0.085 12.9 0.0 0.085 12.9 0.0 3.5 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 VPS53_C PF16854.5 CRK37470.1 - 0.2 11.5 0.2 26 4.6 0.0 2.4 2 0 0 2 2 2 0 Vacuolar protein sorting-associated protein 53 C-terminus ADIP PF11559.8 CRK37470.1 - 0.62 10.1 29.2 0.07 13.2 1.6 4.7 5 0 0 5 5 4 0 Afadin- and alpha -actinin-Binding TEX13 PF15186.6 CRK37470.1 - 0.97 9.1 9.5 2.6 7.7 0.5 2.8 3 0 0 3 3 3 0 Testis-expressed sequence 13 protein family PI3K_P85_iSH2 PF16454.5 CRK37470.1 - 1.1 8.8 10.8 12 5.4 0.4 3.9 3 2 0 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Tropomyosin_1 PF12718.7 CRK37470.1 - 1.2 9.3 24.1 0.31 11.2 1.4 4.2 4 1 0 4 4 3 0 Tropomyosin like KASH_CCD PF14662.6 CRK37470.1 - 1.4 8.7 18.4 4.6 7.0 0.2 4.1 5 0 0 5 5 4 0 Coiled-coil region of CCDC155 or KASH CCDC74_C PF14917.6 CRK37470.1 - 2.9 8.4 8.1 28 5.3 0.9 3.9 3 1 0 3 3 3 0 Coiled coil protein 74, C terminal HAUS-augmin3 PF14932.6 CRK37470.1 - 3.1 7.3 19.8 1.5 8.3 2.1 3.5 3 0 0 3 3 3 0 HAUS augmin-like complex subunit 3 BRE1 PF08647.11 CRK37470.1 - 3.3 7.8 17.1 9.6 6.4 3.4 3.7 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase Syntaxin-6_N PF09177.11 CRK37470.1 - 3.4 8.3 9.6 31 5.2 0.8 4.3 4 1 0 4 4 3 0 Syntaxin 6, N-terminal DUF4391 PF14335.6 CRK37470.1 - 4.2 7.0 10.1 6.6 6.4 1.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4391) SHE3 PF17078.5 CRK37470.1 - 6.6 6.4 8.6 65 3.1 0.0 3.9 3 1 1 4 4 4 0 SWI5-dependent HO expression protein 3 EzrA PF06160.12 CRK37470.1 - 10 4.2 8.5 3.3 5.8 0.7 2.5 3 0 0 3 3 3 0 Septation ring formation regulator, EzrA Aldedh PF00171.22 CRK37471.1 - 3.2e-91 306.1 1.6 4.3e-79 266.2 0.2 2.1 1 1 1 2 2 2 2 Aldehyde dehydrogenase family DASH_Dad1 PF08649.10 CRK37471.1 - 8.4e-26 89.9 2.0 1.5e-25 89.2 2.0 1.4 1 0 0 1 1 1 1 DASH complex subunit Dad1 DASH_Dad1 PF08649.10 CRK37472.1 - 8.9e-27 93.1 2.0 1.2e-26 92.7 2.0 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 DASH_Dad4 PF08650.10 CRK37472.1 - 0.033 14.2 0.2 0.055 13.4 0.2 1.3 1 0 0 1 1 1 0 DASH complex subunit Dad4 CK2S PF15011.6 CRK37472.1 - 0.036 14.0 0.0 0.044 13.7 0.0 1.1 1 0 0 1 1 1 0 Casein Kinase 2 substrate WVELL PF14043.6 CRK37472.1 - 0.092 12.6 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 WVELL protein V_ATPase_I PF01496.19 CRK37472.1 - 0.11 10.4 0.1 0.11 10.3 0.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ras PF00071.22 CRK37474.1 - 3.7e-47 159.9 0.0 5.5e-47 159.4 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CRK37474.1 - 8.6e-20 71.2 0.0 2.1e-19 69.9 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CRK37474.1 - 4.2e-05 23.1 0.0 8.5e-05 22.1 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_7 PF12775.7 CRK37474.1 - 0.066 12.7 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Skp1_POZ PF03931.15 CRK37475.1 - 1.3e-12 47.7 0.0 6.3e-05 23.1 0.0 2.3 2 0 0 2 2 2 2 Skp1 family, tetramerisation domain Zot PF05707.12 CRK37475.1 - 0.027 14.1 0.0 6.4 6.4 0.0 2.3 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) RE_NgoFVII PF09565.10 CRK37475.1 - 0.028 13.8 0.0 5.1 6.3 0.0 2.2 2 0 0 2 2 2 0 NgoFVII restriction endonuclease OAS1_C PF10421.9 CRK37475.1 - 0.064 12.7 0.0 14 5.1 0.0 2.6 3 1 0 3 3 3 0 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus DBR1 PF05011.13 CRK37476.1 - 8.9e-44 149.3 0.0 2.6e-43 147.8 0.0 1.7 1 1 1 2 2 2 1 Lariat debranching enzyme, C-terminal domain GRP PF07172.11 CRK37476.1 - 9.7 7.0 19.5 19 6.0 19.5 1.4 1 0 0 1 1 1 0 Glycine rich protein family LSM PF01423.22 CRK37477.1 - 4e-19 68.1 0.2 4.4e-19 67.9 0.2 1.0 1 0 0 1 1 1 1 LSM domain DBR1 PF05011.13 CRK37478.1 - 6.1e-43 146.6 0.1 1.6e-42 145.2 0.0 1.8 1 1 1 2 2 2 1 Lariat debranching enzyme, C-terminal domain PRMT5_C PF17286.2 CRK37478.1 - 4.6e-15 55.9 0.3 7.4e-15 55.3 0.3 1.3 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Abhydrolase_6 PF12697.7 CRK37478.1 - 1.5e-12 48.6 6.9 1.5e-12 48.6 6.9 2.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CRK37478.1 - 9.4e-12 44.7 0.5 1.7e-11 43.8 0.5 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CRK37478.1 - 2.9e-09 37.0 1.6 7.9e-09 35.5 1.3 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Thioesterase PF00975.20 CRK37478.1 - 0.022 14.9 0.7 0.041 14.0 0.7 1.4 1 0 0 1 1 1 0 Thioesterase domain LSM PF01423.22 CRK37479.1 - 3.7e-19 68.2 0.1 4.2e-19 68.0 0.1 1.1 1 0 0 1 1 1 1 LSM domain PRMT5_C PF17286.2 CRK37480.1 - 6.5e-71 237.8 0.0 1.6e-53 181.2 0.0 2.3 2 0 0 2 2 2 2 PRMT5 oligomerisation domain PRMT5 PF05185.16 CRK37480.1 - 3.7e-66 222.2 0.0 1.3e-65 220.5 0.0 1.8 2 0 0 2 2 2 1 PRMT5 arginine-N-methyltransferase PRMT5_TIM PF17285.2 CRK37480.1 - 2.4e-65 220.3 0.0 3.8e-65 219.6 0.0 1.2 1 0 0 1 1 1 1 PRMT5 TIM barrel domain Abhydrolase_6 PF12697.7 CRK37480.1 - 1.1e-12 49.0 5.9 1.1e-12 49.0 5.9 3.2 3 1 0 3 3 3 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CRK37480.1 - 1.7e-11 43.8 0.2 3.1e-11 43.0 0.2 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CRK37480.1 - 2.5e-09 37.2 1.5 7.7e-09 35.6 1.0 2.0 1 1 0 2 2 2 1 alpha/beta hydrolase fold Thioesterase PF00975.20 CRK37480.1 - 0.022 14.9 0.8 0.044 13.9 0.8 1.5 1 0 0 1 1 1 0 Thioesterase domain OB_NTP_bind PF07717.16 CRK37481.1 - 2.6e-23 82.2 0.1 3.5e-22 78.6 0.0 2.7 3 0 0 3 3 3 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 CRK37481.1 - 2.3e-17 63.3 0.0 5.2e-17 62.1 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CRK37481.1 - 8.3e-11 42.2 0.0 3.7e-10 40.1 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CRK37481.1 - 1.7e-07 31.2 0.1 4.3e-07 29.9 0.1 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CRK37481.1 - 1.3e-05 25.5 0.0 3.4e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 CRK37481.1 - 0.0013 18.4 0.0 0.0049 16.5 0.0 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.14 CRK37481.1 - 0.0027 17.7 0.3 0.019 14.9 0.0 2.2 2 0 0 2 2 2 1 Flavivirus DEAD domain PRMT5_TIM PF17285.2 CRK37482.1 - 1.2e-68 231.1 0.0 1.8e-68 230.5 0.0 1.1 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5 PF05185.16 CRK37482.1 - 4e-66 222.1 0.0 7.2e-66 221.3 0.0 1.4 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 CRK37482.1 - 2.3e-54 184.0 0.0 3.6e-54 183.3 0.0 1.3 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Met_10 PF02475.16 CRK37482.1 - 0.17 11.6 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein OB_NTP_bind PF07717.16 CRK37483.1 - 8.1e-24 83.8 0.1 1.5e-22 79.7 0.0 2.7 3 0 0 3 3 3 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 CRK37483.1 - 2.4e-08 33.9 0.1 5.6e-08 32.8 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CRK37483.1 - 6.7e-08 32.9 0.0 1.4e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 CRK37483.1 - 4.5e-06 26.4 0.1 1.8e-05 24.4 0.0 2.0 2 1 0 2 2 2 1 SRP54-type protein, GTPase domain Helicase_C PF00271.31 CRK37483.1 - 1.9e-05 25.0 0.0 0.00018 21.8 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain T2SSE PF00437.20 CRK37483.1 - 0.00038 19.6 0.0 0.00075 18.6 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein Flavi_DEAD PF07652.14 CRK37483.1 - 0.00086 19.3 0.9 0.0042 17.1 0.1 2.2 2 0 0 2 2 2 1 Flavivirus DEAD domain AAA_30 PF13604.6 CRK37483.1 - 0.0012 18.6 0.0 0.0022 17.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 CRK37483.1 - 0.0045 17.0 0.1 1.3 9.0 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_23 PF13476.6 CRK37483.1 - 0.027 15.0 0.0 0.07 13.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 CRK37483.1 - 0.075 13.1 0.0 0.93 9.5 0.0 2.5 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CRK37483.1 - 0.079 12.5 0.0 0.38 10.2 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region Thr_synth_N PF14821.6 CRK37484.1 - 3.8e-27 94.3 0.0 8.8e-27 93.1 0.0 1.7 1 0 0 1 1 1 1 Threonine synthase N terminus RTP1_C1 PF10363.9 CRK37484.1 - 3.6e-23 81.9 1.4 5.2e-23 81.4 0.1 2.0 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 PALP PF00291.25 CRK37484.1 - 3e-19 69.5 0.0 1.3e-18 67.4 0.0 2.1 2 1 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme His_Phos_2 PF00328.22 CRK37484.1 - 0.019 14.4 0.0 0.041 13.2 0.0 1.4 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) AT_hook PF02178.19 CRK37484.1 - 0.035 14.0 14.7 0.38 10.8 4.0 3.0 2 0 0 2 2 2 0 AT hook motif RTP1_C2 PF10304.9 CRK37484.1 - 0.14 11.9 0.0 0.39 10.4 0.0 1.9 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 2 PBP1_TM PF14812.6 CRK37484.1 - 1.3 9.4 17.6 9.8 6.6 9.7 3.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Fungal_trans PF04082.18 CRK37488.1 - 1.8e-11 43.6 0.1 3.1e-11 42.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK37488.1 - 1.2e-07 31.7 8.6 2.6e-07 30.7 8.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Chorion_2 PF03964.15 CRK37488.1 - 4.8 8.1 10.6 3.1 8.7 1.7 2.6 2 0 0 2 2 2 0 Chorion family 2 DUF2470 PF10615.9 CRK37489.1 - 3e-19 69.4 0.0 5.5e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) Zn_clus PF00172.18 CRK37490.1 - 4 7.6 16.7 0.081 13.1 9.3 2.1 3 0 0 3 3 3 0 Fungal Zn(2)-Cys(6) binuclear cluster domain HMGL-like PF00682.19 CRK37491.1 - 5e-40 137.7 0.0 2.4e-29 102.7 0.0 2.0 2 0 0 2 2 2 2 HMGL-like MCR_C PF04609.12 CRK37491.1 - 0.14 11.2 0.0 4.5 6.3 0.0 2.1 1 1 1 2 2 2 0 Methyl-coenzyme M reductase operon protein C ATP-synt_ab PF00006.25 CRK37492.1 - 1.1e-64 218.0 0.0 1.6e-64 217.5 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 CRK37492.1 - 1.2e-14 54.5 1.4 2.5e-14 53.5 1.4 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF5535 PF17687.1 CRK37492.1 - 0.062 13.5 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5535) DUF4230 PF14014.6 CRK37492.1 - 0.1 12.8 1.9 1.3 9.2 0.7 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4230) Cu_amine_oxid PF01179.20 CRK37495.1 - 7.6e-163 542.2 0.0 1.1e-162 541.7 0.0 1.2 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain HgmA PF04209.13 CRK37495.1 - 1.6e-68 231.4 1.0 2.5e-68 230.7 1.0 1.2 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase p450 PF00067.22 CRK37495.1 - 4e-67 226.9 0.0 5.1e-67 226.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Dabb PF07876.12 CRK37495.1 - 8.3e-12 45.6 0.0 3.4e-11 43.6 0.0 2.1 2 0 0 2 2 2 1 Stress responsive A/B Barrel Domain DUF3418 PF11898.8 CRK37495.1 - 0.019 13.7 0.0 0.026 13.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3418) DUF3433 PF11915.8 CRK37496.1 - 3.1e-30 104.5 16.7 2.5e-18 66.3 1.8 3.6 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) DUF4381 PF14316.6 CRK37496.1 - 0.43 10.8 7.4 2.3 8.5 0.5 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) E1-E2_ATPase PF00122.20 CRK37497.1 - 8.3e-37 126.4 2.5 2.8e-36 124.7 2.5 2.0 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 CRK37497.1 - 3.1e-34 118.3 2.4 3.1e-34 118.3 2.4 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 CRK37497.1 - 2.4e-19 69.2 0.0 6.6e-19 67.8 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CRK37497.1 - 6.4e-17 62.5 0.0 2.2e-16 60.8 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CRK37497.1 - 6.9e-10 38.5 0.1 2.4e-08 33.6 0.0 2.5 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CRK37497.1 - 2.9e-05 24.0 0.2 0.00019 21.3 0.6 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Phage_holin_3_6 PF07332.11 CRK37497.1 - 0.0021 18.1 2.3 0.099 12.7 0.6 3.2 3 0 0 3 3 3 1 Putative Actinobacterial Holin-X, holin superfamily III Abhydrolase_9_N PF15420.6 CRK37497.1 - 0.092 12.7 3.9 3.7 7.5 0.2 3.2 3 0 0 3 3 3 0 Alpha/beta-hydrolase family N-terminus PAP_assoc PF03828.19 CRK37499.1 - 7.3e-12 45.3 0.1 1.3e-11 44.5 0.1 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 CRK37499.1 - 1.3e-05 25.4 0.0 2.6e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Sugar_tr PF00083.24 CRK37501.1 - 2.1e-106 356.5 15.1 2.6e-106 356.2 15.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK37501.1 - 3.6e-19 68.9 22.6 5.1e-19 68.4 17.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF554 PF04474.12 CRK37501.1 - 3.2 7.2 7.8 0.15 11.5 2.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF554) Peptidase_S10 PF00450.22 CRK37503.1 - 2e-46 159.2 0.0 5.3e-40 138.1 0.0 2.0 1 1 1 2 2 2 2 Serine carboxypeptidase Glyco_hydro_28 PF00295.17 CRK37504.1 - 1.8e-11 43.7 7.5 8.3e-09 34.9 0.7 2.4 1 1 0 2 2 2 2 Glycosyl hydrolases family 28 Beta_helix PF13229.6 CRK37504.1 - 0.0045 16.8 11.0 0.15 11.9 8.0 2.6 1 1 1 2 2 2 1 Right handed beta helix region Iso_dh PF00180.20 CRK37506.1 - 3.2e-85 286.3 0.0 3.7e-85 286.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase MFS_1 PF07690.16 CRK37508.1 - 2.7e-23 82.5 34.8 3.2e-19 69.1 11.9 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2070 PF09843.9 CRK37508.1 - 8 4.6 14.4 0.024 13.0 0.8 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) Fungal_trans PF04082.18 CRK37510.1 - 3.1e-19 69.0 1.5 5.1e-19 68.3 1.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK37512.1 - 0.054 13.6 2.9 0.094 12.9 2.9 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Arm_APC_u3 PF16629.5 CRK37512.1 - 0.44 10.1 4.4 0.26 10.8 1.0 1.9 1 1 1 2 2 2 0 Armadillo-associated region on APC ABC_tran PF00005.27 CRK37513.1 - 1.8e-54 183.9 0.3 2.9e-30 105.6 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 CRK37513.1 - 9.1e-20 71.0 36.4 4.9e-10 39.0 12.5 2.4 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 CRK37513.1 - 1e-14 55.1 0.9 0.00023 21.1 0.0 4.3 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CRK37513.1 - 3.5e-12 46.2 0.1 0.00062 19.3 0.0 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CRK37513.1 - 5.6e-06 27.0 0.3 0.089 13.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 CRK37513.1 - 1.1e-05 25.1 0.7 0.23 11.2 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CRK37513.1 - 1.8e-05 24.7 0.1 0.0029 17.5 0.1 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_30 PF13604.6 CRK37513.1 - 0.00014 21.7 0.5 0.62 9.8 0.1 2.8 2 1 0 2 2 2 2 AAA domain NB-ARC PF00931.22 CRK37513.1 - 0.00031 20.0 3.1 0.82 8.8 0.3 3.5 3 1 0 3 3 3 1 NB-ARC domain AAA_22 PF13401.6 CRK37513.1 - 0.00031 21.0 0.3 1.2 9.4 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_24 PF13479.6 CRK37513.1 - 0.00056 19.7 0.0 1.2 8.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 CRK37513.1 - 0.00058 19.6 0.0 4.5 7.0 0.0 4.2 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_16 PF13191.6 CRK37513.1 - 0.00059 20.3 0.0 0.042 14.2 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain SRP54 PF00448.22 CRK37513.1 - 0.0016 18.1 1.2 1.3 8.6 0.2 2.4 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 CRK37513.1 - 0.0051 16.1 0.3 2.5 7.3 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin SbcCD_C PF13558.6 CRK37513.1 - 0.011 15.9 0.2 13 6.1 0.1 3.8 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit MukB PF04310.12 CRK37513.1 - 0.017 14.9 0.2 4 7.2 0.0 3.0 3 0 0 3 3 3 0 MukB N-terminal AAA_14 PF13173.6 CRK37513.1 - 0.028 14.5 0.0 8.6 6.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 CRK37513.1 - 0.028 14.4 0.2 0.64 10.0 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 CRK37513.1 - 0.029 14.8 1.2 8.2 6.9 0.2 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 CRK37513.1 - 0.03 14.1 0.1 8 6.1 0.1 2.5 3 0 0 3 3 3 0 AAA ATPase domain AAA_13 PF13166.6 CRK37513.1 - 0.045 12.4 0.0 5.5 5.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 CRK37513.1 - 0.085 13.1 0.1 1.5 9.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 CRK37513.1 - 0.092 11.8 0.5 0.77 8.8 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Mg_chelatase PF01078.21 CRK37513.1 - 0.11 11.8 0.9 8 5.8 0.1 2.9 2 1 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 CRK37513.1 - 0.13 12.8 0.1 10 6.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 CRK37513.1 - 0.15 12.4 0.1 35 4.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 CRK37513.1 - 0.18 11.4 0.1 13 5.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 CRK37513.1 - 0.19 10.8 0.1 8.8 5.4 0.0 2.4 2 0 0 2 2 2 0 G-protein alpha subunit PduV-EutP PF10662.9 CRK37513.1 - 0.27 11.0 1.4 2.1 8.1 0.0 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation MFS_1 PF07690.16 CRK37516.1 - 3.9e-14 52.4 26.8 4.8e-14 52.1 26.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Ank_4 PF13637.6 CRK37517.1 - 1.7e-11 44.4 0.0 0.0012 19.4 0.0 5.8 5 1 1 6 6 6 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CRK37517.1 - 6.9e-11 42.6 0.0 0.011 16.3 0.0 5.1 4 1 0 5 5 5 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CRK37517.1 - 6.2e-09 35.4 0.6 0.46 11.2 0.0 6.8 8 0 0 8 8 8 3 Ankyrin repeat Ank_5 PF13857.6 CRK37517.1 - 4.7e-06 26.8 0.0 7.7 7.0 0.0 5.4 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 CRK37517.1 - 1.2e-05 25.5 1.3 0.51 10.9 0.0 5.6 5 2 0 5 5 5 2 Ankyrin repeat SDA1 PF05285.12 CRK37518.1 - 5.1 6.4 20.2 11 5.3 20.2 1.5 1 0 0 1 1 1 0 SDA1 Pyr_redox_2 PF07992.14 CRK37519.1 - 5.2e-17 62.0 0.0 6.7e-11 42.0 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CRK37519.1 - 8.6e-07 28.4 0.2 2.6e-05 23.5 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 CRK37519.1 - 1.1e-05 24.9 0.0 0.068 12.4 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CRK37519.1 - 1.5e-05 25.0 1.3 0.022 14.7 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 CRK37519.1 - 0.0003 20.0 1.1 0.089 11.8 0.7 2.1 1 1 1 2 2 2 2 Lycopene cyclase protein GIDA PF01134.22 CRK37519.1 - 0.00066 18.9 0.0 0.11 11.6 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A DAO PF01266.24 CRK37519.1 - 0.0022 17.7 0.5 0.22 11.0 0.3 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CRK37519.1 - 0.003 17.7 0.1 0.042 14.1 0.2 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 CRK37519.1 - 0.01 14.6 0.2 0.064 11.9 0.1 2.0 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.24 CRK37519.1 - 0.04 13.0 0.1 0.59 9.2 0.1 2.5 3 0 0 3 3 3 0 FAD binding domain MSA_2 PF00985.17 CRK37520.1 - 6 7.2 24.0 37 4.6 21.7 2.1 2 0 0 2 2 2 0 Merozoite Surface Antigen 2 (MSA-2) family SBBP PF06739.11 CRK37521.1 - 0.075 13.1 0.1 0.33 11.0 0.1 2.1 1 0 0 1 1 1 0 Beta-propeller repeat NIT PF08376.10 CRK37522.1 - 0.16 12.4 0.9 3.4 8.0 0.0 2.1 1 1 1 2 2 2 0 Nitrate and nitrite sensing PNP_UDP_1 PF01048.20 CRK37523.1 - 8.7e-18 64.4 0.2 1.2e-16 60.6 0.2 2.3 1 1 0 1 1 1 1 Phosphorylase superfamily DUF4245 PF14030.6 CRK37526.1 - 0.021 14.8 0.7 0.022 14.8 0.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4245) COesterase PF00135.28 CRK37527.1 - 4.7e-40 137.9 0.3 5.7e-40 137.6 0.3 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 CRK37527.1 - 0.00037 20.4 0.6 0.0039 17.1 0.6 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold NMO PF03060.15 CRK37528.1 - 5.8e-30 104.8 15.3 1.9e-29 103.1 15.3 1.8 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 CRK37528.1 - 3.6e-08 32.8 7.2 7.9e-08 31.7 7.2 1.5 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 CRK37528.1 - 1.2e-06 27.8 7.5 2e-06 27.1 7.5 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 CRK37528.1 - 0.0024 17.1 4.1 0.0036 16.5 4.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase SseB_C PF14581.6 CRK37528.1 - 0.09 12.9 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 SseB protein C-terminal domain DUF2148 PF09918.9 CRK37528.1 - 0.93 9.6 5.0 0.3 11.2 0.6 2.4 2 1 0 2 2 2 0 Uncharacterized protein containing a ferredoxin domain (DUF2148) ArnB_C PF18677.1 CRK37529.1 - 1.3 9.2 7.3 0.23 11.6 1.2 2.5 3 0 0 3 3 3 0 Archaellum regulatory network B, C-terminal domain Peptidase_M14 PF00246.24 CRK37530.1 - 8e-80 268.7 0.0 9.8e-80 268.4 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Glyco_hydro_12 PF01670.16 CRK37531.1 - 4.8e-17 62.7 5.6 7e-17 62.1 5.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 CBM_1 PF00734.18 CRK37531.1 - 2.6e-11 43.3 15.1 2.6e-11 43.3 15.1 2.9 3 0 0 3 3 3 1 Fungal cellulose binding domain Polyoma_coat2 PF00761.20 CRK37531.1 - 0.069 12.9 0.4 0.13 12.0 0.0 1.5 2 0 0 2 2 2 0 Polyomavirus coat protein Fungal_trans PF04082.18 CRK37532.1 - 3.4e-08 32.8 0.0 1e-07 31.3 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK37532.1 - 9.5e-07 28.8 10.6 9.5e-07 28.8 10.6 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BES1_N PF05687.13 CRK37532.1 - 2.3 8.6 4.8 4.3 7.7 4.8 1.3 1 0 0 1 1 1 0 BES1/BZR1 plant transcription factor, N-terminal Cellulase PF00150.18 CRK37536.1 - 1.4e-18 67.3 1.1 1.9e-18 66.9 1.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 CRK37536.1 - 1.6e-12 47.1 13.4 3.9e-12 45.9 13.4 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Glyco_hydro_2_C PF02836.17 CRK37536.1 - 2.6e-05 23.5 0.1 0.00017 20.8 0.0 2.2 2 1 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.15 CRK37536.1 - 0.00028 20.4 0.1 0.001 18.5 0.1 1.9 1 1 0 1 1 1 1 Beta-galactosidase Glyco_hydro_10 PF00331.20 CRK37536.1 - 0.0076 15.4 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Toxin_7 PF05980.12 CRK37536.1 - 0.1 12.9 2.2 0.18 12.1 2.2 1.4 1 0 0 1 1 1 0 Toxin 7 Med3 PF11593.8 CRK37536.1 - 0.94 8.6 6.8 1.3 8.1 6.8 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Mucin PF01456.17 CRK37536.1 - 1.7 8.6 24.4 3 7.8 24.4 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein PAF-AH_p_II PF03403.13 CRK37538.1 - 1.1e-17 63.7 0.0 7.3e-11 41.2 0.0 2.2 1 1 1 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_6 PF12697.7 CRK37538.1 - 2.4e-05 25.1 1.5 2.4e-05 25.1 1.5 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 CRK37538.1 - 0.00031 19.7 0.1 0.00081 18.4 0.0 1.7 1 1 1 2 2 2 1 Chlorophyllase enzyme Abhydrolase_5 PF12695.7 CRK37538.1 - 0.0047 16.7 0.0 0.31 10.8 0.1 2.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CRK37538.1 - 0.0061 15.9 0.0 0.3 10.3 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Lipase_3 PF01764.25 CRK37538.1 - 0.02 14.7 0.1 0.033 14.0 0.1 1.3 1 0 0 1 1 1 0 Lipase (class 3) Peptidase_S9 PF00326.21 CRK37538.1 - 0.052 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 CRK37538.1 - 0.056 13.3 0.0 0.18 11.7 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 CRK37538.1 - 0.06 13.0 0.1 0.24 11.0 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold Esterase PF00756.20 CRK37538.1 - 0.074 12.7 0.0 0.089 12.4 0.0 1.2 1 0 0 1 1 1 0 Putative esterase DUF2974 PF11187.8 CRK37538.1 - 0.083 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) PGAP1 PF07819.13 CRK37538.1 - 0.22 11.2 0.0 0.39 10.4 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DUF3659 PF12396.8 CRK37540.1 - 8.6e-146 474.0 73.7 9.3e-20 70.3 1.1 9.6 9 0 0 9 9 9 9 Protein of unknown function (DUF3659) GCV_T_C PF08669.11 CRK37540.1 - 0.02 14.8 1.5 25 4.9 0.1 4.8 3 1 1 4 4 4 0 Glycine cleavage T-protein C-terminal barrel domain Mis12 PF05859.12 CRK37540.1 - 2.5 8.1 17.0 55 3.8 2.2 5.1 3 1 1 4 4 4 0 Mis12 protein Phasin_2 PF09361.10 CRK37540.1 - 4.4 7.6 45.6 0.11 12.7 12.3 5.3 3 1 2 5 5 5 0 Phasin protein DUF3659 PF12396.8 CRK37541.1 - 2.9e-14 52.7 2.0 7.3e-11 41.8 0.3 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3659) PAT1 PF09770.9 CRK37541.1 - 1.3 7.2 17.6 1.6 6.9 17.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AP3D1 PF06375.11 CRK37542.1 - 0.084 13.1 2.2 2.7 8.2 1.7 2.2 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 Pestivirus_E2 PF16329.5 CRK37545.1 - 0.002 17.1 0.4 0.002 17.1 0.4 1.0 1 0 0 1 1 1 1 Pestivirus envelope glycoprotein E2 Peptidase_M28 PF04389.17 CRK37548.1 - 2.4e-37 128.6 0.0 3.9e-37 127.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 CRK37548.1 - 9.5e-08 32.0 0.1 3.9e-07 30.0 0.0 2.1 2 1 0 2 2 2 1 Peptidase family M20/M25/M40 DUF2740 PF10872.8 CRK37548.1 - 0.17 11.8 0.1 2.1 8.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2740) adh_short PF00106.25 CRK37549.1 - 1.8e-18 66.7 0.0 1.3e-16 60.6 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CRK37549.1 - 1.7e-09 37.6 0.0 3.9e-09 36.4 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK37549.1 - 0.00017 21.5 0.1 0.0024 17.8 0.0 2.0 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 CRK37549.1 - 0.0095 15.4 0.0 0.013 15.0 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TIR-like PF10137.9 CRK37549.1 - 0.05 13.6 0.0 0.076 13.0 0.0 1.3 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain Shikimate_DH PF01488.20 CRK37549.1 - 0.089 12.8 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 CRK37549.1 - 0.11 12.4 0.0 2.3 8.1 0.0 2.1 2 0 0 2 2 2 0 NAD(P)H-binding TTL PF03133.15 CRK37550.1 - 3.5e-31 108.4 0.0 1.3e-30 106.6 0.0 1.7 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 CRK37550.1 - 0.00026 20.3 0.0 0.00048 19.5 0.0 1.3 1 0 0 1 1 1 1 YheC/D like ATP-grasp Dala_Dala_lig_C PF07478.13 CRK37550.1 - 0.0033 17.0 0.0 0.016 14.8 0.0 1.9 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus Phage_TAC_4 PF08748.11 CRK37550.1 - 0.15 12.4 0.0 0.37 11.1 0.0 1.6 1 0 0 1 1 1 0 Phage tail assembly chaperone PS-DH PF14765.6 CRK37551.1 - 1.9e-45 155.4 0.0 3.5e-45 154.5 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 CRK37551.1 - 1.3e-43 149.7 0.0 2.6e-43 148.8 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 CRK37551.1 - 4.3e-39 134.3 0.0 1e-38 133.0 0.0 1.7 1 0 0 1 1 1 1 KR domain ketoacyl-synt PF00109.26 CRK37551.1 - 3.1e-22 79.4 1.4 4.1e-15 56.0 1.0 2.7 2 1 1 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain KAsynt_C_assoc PF16197.5 CRK37551.1 - 1.5e-13 51.2 0.0 4.6e-13 49.6 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension SAT PF16073.5 CRK37551.1 - 4.4e-05 23.3 0.7 0.061 13.0 0.1 2.9 3 0 0 3 3 3 2 Starter unit:ACP transacylase in aflatoxin biosynthesis PP-binding PF00550.25 CRK37551.1 - 7e-05 23.1 0.0 0.00015 22.0 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.25 CRK37551.1 - 0.012 15.0 0.0 0.039 13.4 0.0 1.9 1 0 0 1 1 1 0 short chain dehydrogenase DprA_WH PF17782.1 CRK37551.1 - 0.24 11.6 0.9 80 3.5 0.0 3.7 3 0 0 3 3 3 0 DprA winged helix domain Promethin PF16015.5 CRK37552.1 - 3.4e-34 117.0 15.8 4e-34 116.7 15.8 1.1 1 0 0 1 1 1 1 Promethin Pectate_lyase PF03211.13 CRK37553.1 - 5.2e-84 280.8 11.2 7.5e-84 280.3 11.2 1.2 1 0 0 1 1 1 1 Pectate lyase RAI16-like PF10257.9 CRK37553.1 - 2.2e-71 240.6 1.2 3.1e-71 240.2 1.2 1.2 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein GMC_oxred_N PF00732.19 CRK37554.1 - 3.6e-52 177.6 0.4 4.8e-52 177.2 0.4 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CRK37554.1 - 6.8e-37 127.2 0.0 2e-36 125.7 0.0 1.8 2 0 0 2 2 2 1 GMC oxidoreductase Lycopene_cycl PF05834.12 CRK37554.1 - 0.00066 18.8 2.5 0.00096 18.3 0.4 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 CRK37554.1 - 0.009 16.2 0.4 0.021 15.0 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CRK37554.1 - 0.014 14.9 1.8 0.048 13.2 0.5 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 CRK37554.1 - 0.03 13.6 1.3 2 7.6 0.6 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CRK37554.1 - 0.042 13.1 0.2 0.22 10.7 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HHH PF00633.23 CRK37554.1 - 0.068 13.1 0.2 1 9.3 0.0 2.6 2 0 0 2 2 2 0 Helix-hairpin-helix motif Peptidase_C25 PF01364.18 CRK37557.1 - 3.3e-109 365.5 0.0 4e-109 365.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C25 Propeptide_C25 PF08126.11 CRK37557.1 - 0.15 11.1 0.5 15 4.6 0.0 3.1 3 0 0 3 3 3 0 Propeptide_C25 Ank_2 PF12796.7 CRK37560.1 - 7.7e-46 154.6 11.2 4e-12 46.6 0.2 6.4 2 2 6 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CRK37560.1 - 9e-36 121.8 8.2 2.4e-07 31.2 0.0 9.6 4 2 7 11 11 11 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 CRK37560.1 - 4.3e-32 106.6 9.0 0.004 17.5 0.0 12.8 13 0 0 13 13 13 7 Ankyrin repeat Ank_5 PF13857.6 CRK37560.1 - 2.7e-24 84.9 11.1 0.00011 22.4 0.1 9.8 5 3 6 11 11 11 7 Ankyrin repeats (many copies) Ank PF00023.30 CRK37560.1 - 7.7e-18 64.1 33.2 0.11 13.0 0.1 12.1 11 1 1 12 12 12 9 Ankyrin repeat DUF2773 PF10971.8 CRK37560.1 - 0.014 15.5 0.3 14 5.9 0.0 4.0 4 1 0 4 4 4 0 Protein of unknown function (DUF2773) MutS_III PF05192.18 CRK37560.1 - 0.035 14.3 0.1 12 6.0 0.0 3.6 3 1 1 4 4 4 0 MutS domain III NPV_P10 PF05531.12 CRK37560.1 - 0.096 13.2 0.0 20 5.7 0.0 2.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Actin PF00022.19 CRK37561.1 - 1.1e-34 119.7 0.0 1.4e-34 119.4 0.0 1.1 1 0 0 1 1 1 1 Actin Ribosomal_L5_C PF00673.21 CRK37561.1 - 1.1e-17 63.9 0.0 1.6e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 CRK37561.1 - 0.013 15.8 0.1 0.022 15.1 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein L5 Cpn60_TCP1 PF00118.24 CRK37564.1 - 6.9e-25 87.6 1.4 7.5e-25 87.5 1.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family GNAT_acetyltran PF12746.7 CRK37564.1 - 0.02 14.4 0.1 0.028 14.0 0.1 1.2 1 1 0 1 1 1 0 GNAT acetyltransferase FtsA PF14450.6 CRK37564.1 - 0.044 14.2 1.0 0.054 13.9 1.0 1.1 1 0 0 1 1 1 0 Cell division protein FtsA Redoxin PF08534.10 CRK37566.1 - 3.6e-09 36.5 0.0 3.8e-09 36.4 0.0 1.0 1 0 0 1 1 1 1 Redoxin FAD_binding_2 PF00890.24 CRK37567.1 - 1.6e-80 271.3 1.4 1.9e-80 271.0 1.4 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 CRK37567.1 - 9.1e-10 38.6 0.1 1.4e-09 38.0 0.1 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Cgr1 PF03879.14 CRK37568.1 - 0.025 15.0 4.6 0.025 14.9 4.6 1.0 1 0 0 1 1 1 0 Cgr1 family DPM3 PF08285.11 CRK37569.1 - 0.17 12.1 1.0 0.25 11.6 1.0 1.3 1 0 0 1 1 1 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Aldedh PF00171.22 CRK37571.1 - 2.1e-11 43.0 0.0 2.2e-11 42.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family HopW1-1 PF15457.6 CRK37571.1 - 0.15 11.3 0.0 0.16 11.2 0.0 1.0 1 0 0 1 1 1 0 Type III T3SS secreted effector HopW1-1/HopPmaA TSC22 PF01166.18 CRK37573.1 - 0.002 18.4 0.4 0.058 13.7 0.0 2.3 2 1 0 2 2 2 2 TSC-22/dip/bun family eIF2A PF08662.11 CRK37575.1 - 1.2e-13 51.4 0.1 1.3e-12 48.0 0.1 1.9 1 1 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 CRK37575.1 - 0.00071 20.3 0.8 0.029 15.2 0.2 2.2 2 0 0 2 2 2 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK37575.1 - 0.037 14.3 0.1 6.6 7.1 0.0 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain AP2 PF00847.20 CRK37575.1 - 0.24 11.7 1.7 2.9 8.2 0.4 2.1 2 0 0 2 2 2 0 AP2 domain DEAD PF00270.29 CRK37577.1 - 0.025 14.3 0.0 0.028 14.2 0.0 1.1 1 0 0 1 1 1 0 DEAD/DEAH box helicase 2-Hacid_dh_C PF02826.19 CRK37578.1 - 2.9e-20 72.4 0.0 3.1e-20 72.3 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 CRK37578.1 - 0.0011 18.3 0.4 0.0012 18.1 0.4 1.1 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain XdhC_C PF13478.6 CRK37578.1 - 0.0097 16.4 0.0 0.011 16.3 0.0 1.1 1 0 0 1 1 1 1 XdhC Rossmann domain UDPG_MGDP_dh_C PF03720.15 CRK37578.1 - 0.011 16.2 0.0 0.014 15.8 0.0 1.1 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 3HCDH_N PF02737.18 CRK37578.1 - 0.018 15.0 0.1 0.02 14.7 0.1 1.1 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 CRK37578.1 - 0.024 14.8 0.0 0.025 14.7 0.0 1.1 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase GFO_IDH_MocA PF01408.22 CRK37578.1 - 0.049 14.5 0.0 0.074 13.9 0.0 1.3 1 1 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Rossmann-like PF10727.9 CRK37578.1 - 0.065 13.1 0.0 0.083 12.8 0.0 1.2 1 0 0 1 1 1 0 Rossmann-like domain NAD_binding_7 PF13241.6 CRK37578.1 - 0.096 13.1 0.1 0.1 13.1 0.1 1.1 1 0 0 1 1 1 0 Putative NAD(P)-binding F420_oxidored PF03807.17 CRK37578.1 - 0.1 13.2 0.0 0.12 13.0 0.0 1.2 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent zf_C2H2_10 PF18414.1 CRK37578.1 - 0.33 10.5 1.2 0.64 9.6 0.7 1.7 1 1 0 1 1 1 0 C2H2 type zinc-finger DUF155 PF02582.14 CRK37581.1 - 5e-09 36.5 0.4 5.8e-09 36.3 0.4 1.1 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 RPS31 PF17067.5 CRK37596.1 - 0.13 12.4 2.9 0.17 12.0 2.7 1.3 1 1 0 1 1 1 0 Ribosomal protein S31e PseudoU_synth_1 PF01416.20 CRK37599.1 - 2.5e-08 34.3 0.1 6.1e-07 29.9 0.0 2.4 2 1 0 2 2 2 1 tRNA pseudouridine synthase Borrelia_P83 PF05262.11 CRK37599.1 - 0.0092 14.5 2.9 0.012 14.1 2.9 1.1 1 0 0 1 1 1 1 Borrelia P83/100 protein Roughex PF06020.11 CRK37599.1 - 0.21 10.6 1.5 0.24 10.5 1.5 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Cas_Cmr3 PF09700.10 CRK37599.1 - 0.5 9.7 5.6 0.15 11.5 2.6 1.5 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cmr3) PBP_N PF17093.5 CRK37599.1 - 1.7 8.9 10.6 4.6 7.5 3.3 2.3 2 0 0 2 2 2 0 Penicillin-binding protein N-terminus Peptidase_M14 PF00246.24 CRK37606.1 - 0.033 14.0 0.0 0.034 14.0 0.0 1.0 1 0 0 1 1 1 0 Zinc carboxypeptidase Nitroreductase PF00881.24 CRK37606.1 - 0.039 14.0 0.1 0.06 13.4 0.1 1.4 1 1 1 2 2 2 0 Nitroreductase family Response_reg PF00072.24 CRK37607.1 - 9e-05 22.6 0.1 0.00014 22.0 0.1 1.4 1 0 0 1 1 1 1 Response regulator receiver domain RA PF00788.23 CRK37607.1 - 0.033 14.8 0.3 0.069 13.8 0.0 1.6 2 0 0 2 2 2 0 Ras association (RalGDS/AF-6) domain GAD PF02938.14 CRK37607.1 - 0.044 14.0 0.0 0.052 13.8 0.0 1.1 1 0 0 1 1 1 0 GAD domain Glyco_trans_1_3 PF13528.6 CRK37608.1 - 0.032 13.5 0.0 0.032 13.5 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF981 PF06168.11 CRK37615.1 - 0.0016 18.4 0.0 0.0018 18.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF981) Herpes_UL4 PF03277.13 CRK37619.1 - 0.11 12.1 2.0 0.15 11.7 2.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL4 family Methyltransf_10 PF05971.12 CRK37623.1 - 8.3e-63 212.5 0.0 1.2e-62 212.0 0.0 1.1 1 0 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 CRK37623.1 - 6.3e-05 22.6 0.0 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.16 CRK37623.1 - 0.063 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_18 PF12847.7 CRK37623.1 - 0.075 13.0 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 CRK37623.1 - 0.11 11.9 0.0 0.34 10.3 0.0 1.7 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) OPT PF03169.15 CRK37624.1 - 5.2e-87 292.9 42.9 6e-87 292.7 42.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein AltA1 PF16541.5 CRK37625.1 - 1.6e-23 83.7 0.4 2e-23 83.3 0.4 1.1 1 0 0 1 1 1 1 Alternaria alternata allergen 1 ADH_N PF08240.12 CRK37626.1 - 2.9e-30 104.3 0.7 5e-30 103.6 0.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CRK37626.1 - 6.7e-18 64.9 0.0 1.1e-17 64.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 CRK37626.1 - 0.00046 19.7 0.0 0.00063 19.3 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 CRK37626.1 - 0.0065 17.5 0.0 0.011 16.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 CRK37626.1 - 0.058 12.7 0.0 0.12 11.6 0.0 1.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain MFS_1 PF07690.16 CRK37627.1 - 6.4e-37 127.3 25.5 6.4e-37 127.3 25.5 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Aa_trans PF01490.18 CRK37628.1 - 6.8e-56 189.7 37.6 7.7e-56 189.5 37.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Methyltransf_23 PF13489.6 CRK37630.1 - 9.3e-21 74.4 0.0 1.3e-20 73.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK37630.1 - 1.4e-11 44.9 0.0 4.6e-11 43.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK37630.1 - 2.8e-11 43.4 0.0 3.2e-10 40.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CRK37630.1 - 6.3e-10 39.6 0.0 1.9e-09 38.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK37630.1 - 7e-08 33.1 0.0 1.3e-06 29.1 0.0 2.8 2 2 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.19 CRK37630.1 - 4.5e-05 23.6 0.0 7.7e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase CMAS PF02353.20 CRK37630.1 - 0.02 14.2 0.0 0.044 13.1 0.0 1.5 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase MTS PF05175.14 CRK37630.1 - 0.02 14.4 0.0 0.038 13.5 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_2 PF00891.18 CRK37630.1 - 0.09 12.1 0.0 0.22 10.8 0.0 1.6 2 0 0 2 2 2 0 O-methyltransferase domain PrmA PF06325.13 CRK37630.1 - 0.092 12.1 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 CRK37630.1 - 0.18 11.3 0.0 0.39 10.2 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase DUF4139 PF13598.6 CRK37632.1 - 1.4e-32 113.1 0.3 3.7e-32 111.7 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4139) DUF4140 PF13600.6 CRK37632.1 - 2e-27 95.5 1.8 2e-27 95.5 1.8 3.2 3 0 0 3 3 3 1 N-terminal domain of unknown function (DUF4140) DUF4140 PF13600.6 CRK37633.1 - 2.7e-27 95.1 2.2 2.7e-27 95.1 2.2 3.1 3 0 0 3 3 3 1 N-terminal domain of unknown function (DUF4140) DUF4139 PF13598.6 CRK37633.1 - 1.2e-16 61.1 0.0 1.2e-16 61.1 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4139) Peptidase_M32 PF02074.15 CRK37633.1 - 3.3 6.4 10.4 5.3 5.7 10.4 1.3 1 0 0 1 1 1 0 Carboxypeptidase Taq (M32) metallopeptidase His_Phos_1 PF00300.22 CRK37635.1 - 4.6e-09 36.2 0.0 1.2e-08 34.8 0.0 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) SMYLE_N PF18615.1 CRK37635.1 - 0.016 14.8 0.0 0.02 14.5 0.0 1.1 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain PapJ PF14855.6 CRK37635.1 - 0.24 11.1 0.0 0.36 10.5 0.0 1.2 1 0 0 1 1 1 0 Pilus-assembly fibrillin subunit, chaperone Dynamin_N PF00350.23 CRK37636.1 - 1.2e-29 103.5 0.0 2e-29 102.8 0.0 1.4 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 CRK37636.1 - 5e-21 75.2 0.0 9.2e-21 74.3 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 CRK37636.1 - 1.6e-05 25.0 0.0 0.00036 20.6 0.0 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.18 CRK37636.1 - 0.001 19.2 1.2 0.0045 17.1 0.1 2.6 3 0 0 3 3 3 1 Dynamin GTPase effector domain AAA_21 PF13304.6 CRK37636.1 - 0.051 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 CRK37636.1 - 0.099 12.3 0.1 0.16 11.6 0.1 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 CRK37636.1 - 0.1 12.4 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FeoB_N PF02421.18 CRK37636.1 - 0.12 11.9 0.0 5.9 6.4 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B Glyco_hydro_28 PF00295.17 CRK37637.1 - 1.3e-49 169.1 17.8 1.7e-49 168.7 17.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Glyco_hydro_28 PF00295.17 CRK37638.1 - 1.4e-47 162.3 5.6 2.2e-47 161.7 5.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Epimerase PF01370.21 CRK37639.1 - 5.2e-18 65.4 0.0 7.9e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 CRK37639.1 - 2.7e-12 46.4 0.0 2.9e-11 43.0 0.0 2.3 2 1 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.19 CRK37639.1 - 8.1e-11 41.4 0.0 1.4e-10 40.6 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 CRK37639.1 - 1.3e-07 31.3 0.1 2.2e-07 30.6 0.1 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 CRK37639.1 - 9.5e-06 25.6 0.0 1.8e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 CRK37639.1 - 0.0012 18.3 0.0 0.0047 16.4 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.13 CRK37639.1 - 0.0024 17.4 0.0 0.0052 16.4 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.15 CRK37639.1 - 0.0024 17.0 0.0 0.0033 16.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 CRK37639.1 - 0.013 15.4 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 KR domain RmlD_sub_bind PF04321.17 CRK37639.1 - 0.017 14.3 0.0 0.031 13.4 0.0 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain NMO PF03060.15 CRK37639.1 - 0.093 12.1 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 Nitronate monooxygenase Peptidase_S8 PF00082.22 CRK37640.1 - 1e-41 143.2 4.2 1.7e-41 142.4 4.2 1.3 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 CRK37640.1 - 1.9e-07 31.7 0.0 1.3e-06 29.0 0.0 2.3 2 0 0 2 2 2 1 Fn3-like domain Aldedh PF00171.22 CRK37641.1 - 6.9e-138 460.0 0.0 1e-137 459.5 0.0 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GMC_oxred_N PF00732.19 CRK37641.1 - 7.1e-53 179.9 0.0 1.2e-52 179.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CRK37641.1 - 2.6e-31 109.1 0.1 8.4e-31 107.4 0.0 2.0 2 0 0 2 2 2 1 GMC oxidoreductase ADH_zinc_N PF00107.26 CRK37641.1 - 2.7e-24 85.6 1.4 6.9e-24 84.3 1.4 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CRK37641.1 - 8.5e-20 70.7 0.6 2e-19 69.5 0.6 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DAO PF01266.24 CRK37641.1 - 3.4e-06 26.9 0.1 0.25 10.9 0.0 4.0 4 0 0 4 4 4 2 FAD dependent oxidoreductase LuxC PF05893.14 CRK37641.1 - 0.013 14.6 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) AlaDh_PNT_C PF01262.21 CRK37641.1 - 0.024 13.9 2.2 0.051 12.9 2.2 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 CRK37641.1 - 0.065 14.3 0.1 0.16 13.0 0.1 1.7 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Lycopene_cycl PF05834.12 CRK37641.1 - 0.22 10.6 0.1 0.38 9.7 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Methyltransf_2 PF00891.18 CRK37643.1 - 5.4e-17 61.8 0.0 1.4e-16 60.5 0.0 1.6 1 1 0 1 1 1 1 O-methyltransferase domain Hce2 PF14856.6 CRK37644.1 - 3e-30 104.5 1.5 3.4e-15 56.2 0.0 2.7 3 0 0 3 3 3 2 Pathogen effector; putative necrosis-inducing factor P5CR_dimer PF14748.6 CRK37645.1 - 1.4e-71 237.3 4.3 8.9e-35 119.1 0.4 2.9 2 0 0 2 2 2 2 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 CRK37645.1 - 1.3e-16 61.0 1.8 4.8e-16 59.1 1.8 2.1 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DUF900 PF05990.12 CRK37645.1 - 0.00053 19.6 0.0 0.28 10.7 0.0 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF900) DUF676 PF05057.14 CRK37645.1 - 0.001 18.6 0.0 0.37 10.3 0.0 2.4 2 0 0 2 2 2 2 Putative serine esterase (DUF676) Cutinase PF01083.22 CRK37645.1 - 0.0021 18.0 0.0 2.6 8.0 0.0 2.5 2 0 0 2 2 2 2 Cutinase Ser_hydrolase PF06821.13 CRK37645.1 - 0.0039 17.1 0.4 3.7 7.4 0.1 2.7 2 0 0 2 2 2 2 Serine hydrolase Lipase_3 PF01764.25 CRK37645.1 - 0.016 15.1 0.0 6.8 6.6 0.0 2.7 2 0 0 2 2 2 0 Lipase (class 3) PE-PPE PF08237.11 CRK37645.1 - 0.021 14.4 0.0 3.2 7.2 0.0 2.4 2 0 0 2 2 2 0 PE-PPE domain Palm_thioest PF02089.15 CRK37645.1 - 0.029 14.2 0.0 6.6 6.5 0.0 2.3 2 0 0 2 2 2 0 Palmitoyl protein thioesterase DUF5433 PF17498.2 CRK37645.1 - 0.061 13.5 0.0 20 5.5 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5433) Host_attach PF10116.9 CRK37645.1 - 0.12 13.0 3.4 5.5 7.6 0.1 3.0 3 0 0 3 3 2 0 Protein required for attachment to host cells HEV_ORF1 PF02444.16 CRK37645.1 - 0.12 13.0 1.9 30 5.2 0.3 3.4 2 0 0 2 2 2 0 Hepatitis E virus ORF-2 (Putative capsid protein) Abhydrolase_6 PF12697.7 CRK37645.1 - 1.2 9.7 24.4 0.44 11.1 0.4 4.0 2 2 1 4 4 4 0 Alpha/beta hydrolase family Epimerase PF01370.21 CRK37647.1 - 5.8e-11 42.3 0.0 3.6e-10 39.7 0.0 2.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CRK37647.1 - 2.4e-09 36.6 0.0 3.9e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Ank_5 PF13857.6 CRK37647.1 - 3.4e-08 33.6 0.0 9.6e-08 32.2 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) NAD_binding_10 PF13460.6 CRK37647.1 - 3.1e-07 30.5 0.0 6.2e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 CRK37647.1 - 4.1e-07 29.4 0.0 0.0083 15.3 0.0 2.5 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 CRK37647.1 - 2.1e-05 24.1 0.0 3.8e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Ank_4 PF13637.6 CRK37647.1 - 0.0011 19.5 0.0 0.0041 17.6 0.0 2.1 2 0 0 2 2 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CRK37647.1 - 0.0012 19.3 0.0 0.024 15.2 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) NmrA PF05368.13 CRK37647.1 - 0.0028 17.3 0.0 0.0081 15.7 0.0 1.8 2 0 0 2 2 2 1 NmrA-like family Ribul_P_3_epim PF00834.19 CRK37647.1 - 0.0042 16.5 0.0 23 4.3 0.0 3.5 3 0 0 3 3 3 0 Ribulose-phosphate 3 epimerase family Ank PF00023.30 CRK37647.1 - 0.015 15.7 0.1 0.06 13.8 0.0 2.1 2 0 0 2 2 1 0 Ankyrin repeat DUF3323 PF11796.8 CRK37647.1 - 0.017 15.0 1.7 5.1 6.9 0.2 3.4 3 0 0 3 3 3 0 Protein of unknown function N-terminus (DUF3323) Lipoprotein_3 PF00938.17 CRK37647.1 - 0.023 14.9 0.0 47 4.3 0.0 3.9 4 0 0 4 4 4 0 Lipoprotein Rhabdo_M2 PF04785.12 CRK37647.1 - 0.027 13.8 0.6 1 8.7 0.0 2.6 3 0 0 3 3 3 0 Rhabdovirus matrix protein M2 Ank_3 PF13606.6 CRK37647.1 - 0.042 14.4 0.0 0.23 12.1 0.0 2.4 1 0 0 1 1 1 0 Ankyrin repeat KR PF08659.10 CRK37647.1 - 0.083 12.8 0.1 10 6.0 0.2 2.8 3 0 0 3 3 3 0 KR domain Polysacc_synt_2 PF02719.15 CRK37647.1 - 0.14 11.3 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein SLC3A2_N PF16028.5 CRK37647.1 - 0.16 11.6 3.2 38 3.9 0.0 3.9 4 0 0 4 4 4 0 Solute carrier family 3 member 2 N-terminus Glyco_transf_64 PF09258.10 CRK37648.1 - 1.7e-55 188.0 0.0 2.2e-55 187.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain Glycos_transf_2 PF00535.26 CRK37648.1 - 0.011 15.6 0.1 0.074 12.9 0.1 2.3 1 1 0 1 1 1 0 Glycosyl transferase family 2 DUF4574 PF15141.6 CRK37648.1 - 0.067 13.1 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 Fungal_trans PF04082.18 CRK37649.1 - 8.8e-13 47.9 0.0 1.3e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK37649.1 - 9.9e-06 25.6 7.5 2.1e-05 24.5 7.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 CRK37652.1 - 4.7e-33 114.6 21.0 1.2e-32 113.2 21.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily GRP PF07172.11 CRK37654.1 - 0.19 12.4 24.2 0.24 12.1 24.2 1.3 1 0 0 1 1 1 0 Glycine rich protein family Metallophos PF00149.28 CRK37655.1 - 1e-08 35.9 0.0 1.6e-08 35.3 0.0 1.5 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase Sugar_tr PF00083.24 CRK37657.1 - 1.2e-45 156.3 17.7 1.6e-45 155.9 17.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK37657.1 - 1.9e-33 115.9 45.3 3.3e-30 105.2 27.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5609 PF18429.1 CRK37657.1 - 0.04 13.7 0.0 0.095 12.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5609) Sugar_tr PF00083.24 CRK37659.1 - 3.6e-52 177.7 21.9 1.5e-44 152.6 17.3 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CRK37659.1 - 4.1e-38 131.2 37.2 4.2e-29 101.6 27.5 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily NodS PF05401.11 CRK37659.1 - 0.0087 15.7 0.0 5.8 6.5 0.0 2.6 2 0 0 2 2 2 2 Nodulation protein S (NodS) DUF5609 PF18429.1 CRK37659.1 - 0.054 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5609) DUF2759 PF10958.8 CRK37659.1 - 0.38 10.5 12.0 4.4 7.1 2.1 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2759) AAA PF00004.29 CRK37660.1 - 3.9e-15 56.5 0.0 1.5e-14 54.5 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CRK37660.1 - 0.0078 16.5 1.7 0.15 12.3 0.1 2.6 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 CRK37660.1 - 0.014 15.4 0.0 0.033 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CRK37660.1 - 0.03 14.7 0.9 0.11 12.8 0.2 2.3 2 1 0 2 2 2 0 AAA ATPase domain Med30 PF11315.8 CRK37660.1 - 0.033 14.4 0.1 0.033 14.4 0.1 2.1 2 0 0 2 2 2 0 Mediator complex subunit 30 AAA_11 PF13086.6 CRK37660.1 - 0.089 12.6 11.3 0.18 11.5 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 CRK37660.1 - 0.093 13.3 0.2 0.39 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain GYF PF02213.16 CRK37661.1 - 7.3e-19 67.2 0.2 1.6e-18 66.1 0.2 1.6 1 0 0 1 1 1 1 GYF domain Ion_trans PF00520.31 CRK37661.1 - 3.4e-08 33.0 18.0 8.8e-08 31.7 18.0 1.6 1 1 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 CRK37661.1 - 7e-08 31.6 11.4 1.1e-07 31.0 11.4 1.2 1 0 0 1 1 1 1 Polycystin cation channel TPR_2 PF07719.17 CRK37661.1 - 9.5e-06 25.4 12.0 0.0023 17.9 0.0 4.3 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 CRK37661.1 - 0.0003 21.4 6.5 0.0003 21.4 6.5 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 CRK37661.1 - 0.001 19.1 0.3 4.5 7.7 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 CRK37661.1 - 0.0018 18.9 0.2 0.0018 18.9 0.2 6.0 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 CRK37661.1 - 0.0031 17.8 2.4 0.0031 17.8 2.4 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat GYF_2 PF14237.6 CRK37661.1 - 0.0076 16.0 0.0 0.026 14.3 0.0 2.0 1 0 0 1 1 1 1 GYF domain 2 DUF5044 PF16447.5 CRK37661.1 - 0.015 15.1 0.1 0.035 14.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5044) TPR_1 PF00515.28 CRK37661.1 - 0.051 13.4 3.9 2.1 8.3 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Cyt-b5 PF00173.28 CRK37662.1 - 4.7e-16 58.7 0.0 1e-10 41.6 0.0 4.0 4 0 0 4 4 4 2 Cytochrome b5-like Heme/Steroid binding domain Jiv90 PF14901.6 CRK37662.1 - 0.17 12.1 0.6 6 7.1 0.0 3.0 3 0 0 3 3 3 0 Cleavage inducing molecular chaperone Pol_alpha_B_N PF08418.10 CRK37662.1 - 8.5 6.3 7.5 2.9 7.8 3.6 2.2 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal ABC_tran PF00005.27 CRK37663.1 - 2e-48 164.4 0.1 2.2e-24 86.5 0.1 3.9 2 2 0 2 2 2 2 ABC transporter 4HB PF17947.1 CRK37663.1 - 3.1e-29 100.8 0.3 3.1e-29 100.8 0.3 2.6 2 0 0 2 2 2 1 Four helical bundle domain AAA_21 PF13304.6 CRK37663.1 - 1.2e-17 64.7 0.0 0.00089 19.2 0.0 5.0 4 1 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CRK37663.1 - 1.2e-15 57.5 0.1 0.00016 21.2 0.0 4.0 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CRK37663.1 - 3e-10 40.9 3.3 9.1e-05 23.1 0.2 2.9 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.6 CRK37663.1 - 9.3e-09 34.9 0.0 0.0062 16.2 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CRK37663.1 - 1.7e-08 34.6 0.0 0.00018 21.5 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 CRK37663.1 - 2.9e-07 30.6 0.0 0.0021 18.1 0.0 3.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 CRK37663.1 - 2e-06 28.1 0.0 0.038 14.3 0.0 3.4 3 0 0 3 3 2 2 AAA domain AAA_28 PF13521.6 CRK37663.1 - 3.4e-06 27.4 0.0 0.026 14.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.23 CRK37663.1 - 5.6e-06 26.5 0.0 0.00047 20.3 0.0 3.1 3 0 0 3 3 3 1 Dynamin family AAA_18 PF13238.6 CRK37663.1 - 7.3e-06 26.6 0.0 0.18 12.4 0.0 3.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CRK37663.1 - 1.7e-05 25.3 0.0 0.25 11.7 0.0 3.4 3 0 0 3 3 2 2 AAA ATPase domain AAA_15 PF13175.6 CRK37663.1 - 1.8e-05 24.6 2.9 0.046 13.4 0.0 3.3 2 2 1 3 3 3 2 AAA ATPase domain AAA PF00004.29 CRK37663.1 - 4.7e-05 23.8 0.0 1.4 9.4 0.0 4.0 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) MeaB PF03308.16 CRK37663.1 - 4.9e-05 22.4 0.1 0.24 10.4 0.1 2.5 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 CRK37663.1 - 5.2e-05 23.4 0.0 0.7 10.0 0.0 3.1 2 0 0 2 2 2 2 AAA domain PduV-EutP PF10662.9 CRK37663.1 - 8.8e-05 22.3 0.0 0.053 13.3 0.0 2.8 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.22 CRK37663.1 - 0.0001 22.6 0.0 0.76 10.2 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA_27 PF13514.6 CRK37663.1 - 0.00021 21.0 0.0 0.15 11.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 CRK37663.1 - 0.00028 20.7 0.0 0.96 9.1 0.0 3.1 3 0 0 3 3 3 2 AAA domain G-alpha PF00503.20 CRK37663.1 - 0.00054 19.2 0.1 1.1 8.3 0.0 2.7 3 0 0 3 3 3 2 G-protein alpha subunit AAA_30 PF13604.6 CRK37663.1 - 0.00072 19.3 0.0 3.5 7.3 0.0 3.4 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 CRK37663.1 - 0.0011 18.9 0.0 0.36 10.7 0.0 2.5 2 0 0 2 2 2 1 NACHT domain Rad17 PF03215.15 CRK37663.1 - 0.0025 17.8 0.0 1.4 8.8 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain HEAT PF02985.22 CRK37663.1 - 0.0036 17.4 0.4 22 5.7 0.0 4.3 3 0 0 3 3 3 0 HEAT repeat SbcCD_C PF13558.6 CRK37663.1 - 0.0042 17.3 0.0 1.3 9.3 0.0 3.2 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF87 PF01935.17 CRK37663.1 - 0.005 17.0 1.1 0.94 9.5 0.0 3.5 4 0 0 4 4 3 1 Helicase HerA, central domain Septin PF00735.18 CRK37663.1 - 0.0056 16.0 0.5 2.7 7.2 0.0 3.2 3 0 0 3 3 3 1 Septin cobW PF02492.19 CRK37663.1 - 0.0061 16.2 0.1 7.4 6.1 0.0 3.3 4 0 0 4 4 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.6 CRK37663.1 - 0.0072 16.4 0.0 7 6.7 0.0 3.1 3 0 0 3 3 2 0 AAA domain PRK PF00485.18 CRK37663.1 - 0.0074 16.0 0.0 0.34 10.6 0.0 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family Roc PF08477.13 CRK37663.1 - 0.0081 16.4 0.0 9.3 6.5 0.0 3.2 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase ATPase_2 PF01637.18 CRK37663.1 - 0.013 15.4 0.1 5 7.0 0.0 3.0 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea ATP_bind_1 PF03029.17 CRK37663.1 - 0.019 14.7 0.0 7.2 6.3 0.0 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein HEAT_2 PF13646.6 CRK37663.1 - 0.025 15.0 3.1 1.5 9.2 1.7 3.4 2 1 1 3 3 2 0 HEAT repeats NB-ARC PF00931.22 CRK37663.1 - 0.025 13.8 0.0 1.7 7.8 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain IstB_IS21 PF01695.17 CRK37663.1 - 0.027 14.2 0.0 7.4 6.3 0.0 2.7 2 0 0 2 2 2 0 IstB-like ATP binding protein Cytidylate_kin PF02224.18 CRK37663.1 - 0.034 13.9 0.0 7.2 6.3 0.0 2.7 2 0 0 2 2 2 0 Cytidylate kinase CLP1_P PF16575.5 CRK37663.1 - 0.036 13.8 0.0 1.8 8.3 0.0 2.6 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_7 PF12775.7 CRK37663.1 - 0.041 13.4 0.0 7.2 6.1 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region MukB PF04310.12 CRK37663.1 - 0.051 13.4 0.0 9.5 5.9 0.0 2.4 2 0 0 2 2 2 0 MukB N-terminal AAA_13 PF13166.6 CRK37663.1 - 0.055 12.1 4.1 2.3 6.8 0.0 3.9 4 1 1 5 5 4 0 AAA domain ParcG PF10274.9 CRK37663.1 - 0.064 13.4 0.5 3.3 7.8 0.1 3.0 1 1 1 3 3 3 0 Parkin co-regulated protein T2SSE PF00437.20 CRK37663.1 - 0.076 12.1 0.1 3.5 6.6 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein Mg_chelatase PF01078.21 CRK37663.1 - 0.089 12.2 0.0 4.1 6.7 0.0 2.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Rif1_N PF12231.8 CRK37663.1 - 0.092 11.7 0.2 0.19 10.7 0.2 1.4 1 0 0 1 1 1 0 Rap1-interacting factor 1 N terminal NTPase_1 PF03266.15 CRK37663.1 - 0.093 12.6 0.0 18 5.2 0.1 2.9 2 0 0 2 2 2 0 NTPase Zeta_toxin PF06414.12 CRK37663.1 - 0.094 12.0 0.0 17 4.6 0.0 2.7 2 0 0 2 2 2 0 Zeta toxin Ploopntkinase3 PF18751.1 CRK37663.1 - 0.11 12.4 0.0 22 4.9 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 DAP3 PF10236.9 CRK37663.1 - 0.3 10.2 3.6 3.8 6.6 0.3 2.8 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 HEAT_EZ PF13513.6 CRK37663.1 - 8.2 7.0 10.7 11 6.6 1.4 5.0 6 0 0 6 6 3 0 HEAT-like repeat His_Phos_1 PF00300.22 CRK37664.1 - 3.3e-14 53.0 0.0 9.9e-13 48.2 0.0 2.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF4795 PF16043.5 CRK37664.1 - 0.017 14.7 0.7 0.075 12.6 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) Macro PF01661.21 CRK37665.1 - 5.3e-39 132.9 0.1 9.1e-39 132.2 0.1 1.4 1 0 0 1 1 1 1 Macro domain tRNA-synt_1c PF00749.21 CRK37666.1 - 2.2e-102 342.1 0.1 3.8e-102 341.4 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 CRK37666.1 - 9.5e-34 116.8 0.0 8.3e-33 113.7 0.0 2.5 3 0 0 3 3 3 1 tRNA synthetases class I (E and Q), anti-codon binding domain CFEM PF05730.11 CRK37668.1 - 6.5e-11 42.2 5.7 1e-10 41.5 5.7 1.3 1 0 0 1 1 1 1 CFEM domain Ecm33 PF12454.8 CRK37668.1 - 0.01 16.0 0.2 0.036 14.2 0.2 2.0 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein DUF1180 PF06679.12 CRK37668.1 - 3.2 8.1 5.9 4.5 7.7 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) MAGE_N PF12440.8 CRK37669.1 - 0.0052 17.4 7.3 0.0062 17.2 7.3 1.2 1 0 0 1 1 1 1 Melanoma associated antigen family N terminal Cupin_2 PF07883.11 CRK37670.1 - 2.8e-05 23.7 0.0 4.3e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 CRK37670.1 - 0.00026 20.6 0.0 0.0003 20.4 0.0 1.1 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 CRK37670.1 - 0.033 13.9 0.0 0.048 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) CBM_1 PF00734.18 CRK37671.1 - 2e-09 37.3 17.4 2e-09 37.3 17.4 2.8 2 0 0 2 2 2 1 Fungal cellulose binding domain Glyco_hydro_3_C PF01915.22 CRK37672.1 - 7.2e-50 169.8 0.1 1e-49 169.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 CRK37672.1 - 2.5e-29 102.7 0.0 8.4e-29 100.9 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 CRK37672.1 - 7.1e-22 77.3 0.0 1.3e-21 76.4 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Shisa PF13908.6 CRK37673.1 - 0.025 14.8 0.0 0.029 14.6 0.0 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator CYYR1 PF10873.8 CRK37673.1 - 0.026 15.0 1.7 0.044 14.2 1.7 1.3 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 EphA2_TM PF14575.6 CRK37673.1 - 0.069 14.0 0.0 0.086 13.7 0.0 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Epiglycanin_C PF14654.6 CRK37673.1 - 0.2 11.7 4.5 1 9.5 4.2 2.0 1 1 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region TMIE PF16038.5 CRK37673.1 - 0.23 11.3 1.3 0.32 10.9 1.3 1.2 1 0 0 1 1 1 0 TMIE protein Fungus-induced PF10917.8 CRK37685.1 - 0.073 13.4 0.7 0.13 12.6 0.7 1.4 1 0 0 1 1 1 0 Fungus-induced protein CBM_X2 PF03442.14 CRK37686.1 - 7.8e-05 22.7 0.0 0.0022 18.1 0.0 2.0 2 0 0 2 2 2 1 Carbohydrate binding domain X2 CBM46 PF18448.1 CRK37686.1 - 0.096 13.0 0.0 1.3 9.4 0.0 2.0 1 1 1 2 2 2 0 Carbohydrate binding domain Ank_4 PF13637.6 CRK37693.1 - 0.0025 18.4 0.0 0.0033 18.0 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CRK37693.1 - 0.057 14.0 0.1 0.074 13.7 0.1 1.2 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) DJ-1_PfpI PF01965.24 CRK37694.1 - 0.0099 15.7 0.0 0.012 15.5 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family Dynamin_N PF00350.23 CRK37695.1 - 0.012 15.6 0.1 0.015 15.4 0.1 1.1 1 0 0 1 1 1 0 Dynamin family TniB PF05621.11 CRK37695.1 - 0.13 11.6 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Bacterial TniB protein Roc PF08477.13 CRK37695.1 - 0.2 11.9 0.0 0.27 11.5 0.0 1.2 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase HhH-GPD PF00730.25 CRK37697.1 - 3.1e-05 24.4 0.0 3.6e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Peptidase_S8 PF00082.22 CRK37699.1 - 0.013 14.8 5.4 0.034 13.4 5.4 1.7 1 1 0 1 1 1 0 Subtilase family GFO_IDH_MocA PF01408.22 CRK37701.1 - 0.001 19.9 0.0 0.0012 19.7 0.0 1.1 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold TIP120 PF08623.10 CRK37704.1 - 5.5e-13 49.0 0.0 6.1e-13 48.9 0.0 1.0 1 0 0 1 1 1 1 TATA-binding protein interacting (TIP20) Tfb2 PF03849.14 CRK37705.1 - 4.2e-13 49.0 0.0 4.5e-13 48.9 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb2 Ish1 PF10281.9 CRK37706.1 - 2.2e-20 72.7 1.6 3.8e-11 43.1 0.0 2.7 2 0 0 2 2 2 2 Putative stress-responsive nuclear envelope protein AAA_lid_3 PF17862.1 CRK37706.1 - 1.9e-09 37.2 0.0 3.2e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 CRK37706.1 - 4.1e-09 36.9 0.0 7e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) SAP PF02037.27 CRK37706.1 - 0.016 14.9 0.0 0.26 11.1 0.0 2.7 4 0 0 4 4 4 0 SAP domain Tyrosinase PF00264.20 CRK37707.1 - 1.5e-14 54.9 0.4 1.5e-14 54.8 0.4 1.0 1 0 0 1 1 1 1 Common central domain of tyrosinase DAD PF02109.16 CRK37709.1 - 8.7e-14 51.8 0.0 1e-13 51.6 0.0 1.1 1 0 0 1 1 1 1 DAD family ADSL_C PF10397.9 CRK37710.1 - 9.7e-11 42.1 0.0 1.2e-10 41.7 0.0 1.1 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus Ribosomal_S2 PF00318.20 CRK37712.1 - 1.7e-17 63.4 0.0 2.2e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S2 ILVD_EDD PF00920.21 CRK37715.1 - 5.6e-28 97.8 0.1 6.5e-28 97.6 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family EphA2_TM PF14575.6 CRK37720.1 - 0.01 16.7 0.1 0.012 16.5 0.1 1.1 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain LapA_dom PF06305.11 CRK37720.1 - 0.041 13.7 0.5 0.056 13.3 0.5 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain FeoB_associated PF12669.7 CRK37720.1 - 1.8 9.0 2.9 3.5 8.1 2.9 1.6 1 1 0 1 1 1 0 FeoB-associated Cys-rich membrane protein SKG6 PF08693.10 CRK37720.1 - 3.8 7.0 6.7 7.8 6.0 6.7 1.6 1 1 0 1 1 1 0 Transmembrane alpha-helix domain NMD3 PF04981.13 CRK37723.1 - 1.9e-21 76.7 0.1 2.2e-21 76.5 0.1 1.0 1 0 0 1 1 1 1 NMD3 family 3Beta_HSD PF01073.19 CRK37723.1 - 0.093 11.7 0.0 0.097 11.7 0.0 1.0 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family zf-H2C2_2 PF13465.6 CRK37723.1 - 0.12 12.9 0.2 0.21 12.1 0.2 1.4 1 0 0 1 1 1 0 Zinc-finger double domain Cyto_heme_lyase PF01265.17 CRK37730.1 - 2.3e-19 70.1 0.0 2.5e-19 70.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase MFS_1 PF07690.16 CRK37736.1 - 2.2e-07 30.2 5.8 2.2e-07 30.2 5.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 CRK37736.1 - 0.046 12.0 0.6 0.05 11.9 0.6 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF2964 PF11177.8 CRK37736.1 - 0.064 13.5 0.2 0.088 13.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2964) ELO PF01151.18 CRK37737.1 - 0.00079 19.0 0.0 0.00089 18.9 0.0 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family HET PF06985.11 CRK37738.1 - 5.1e-20 72.3 0.0 5.2e-20 72.3 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) F-box-like PF12937.7 CRK37739.1 - 9.6e-10 38.2 0.0 1.7e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CRK37739.1 - 0.00091 19.0 0.0 0.0018 18.1 0.0 1.5 1 0 0 1 1 1 1 F-box domain Mito_carr PF00153.27 CRK37740.1 - 1.6e-61 204.2 4.2 5.8e-21 74.2 0.1 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF4148 PF13663.6 CRK37740.1 - 0.17 12.1 3.2 0.17 12.1 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) DUF1708 PF08101.11 CRK37741.1 - 1.5e-179 597.7 0.0 2.2e-179 597.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) CHRD PF07452.12 CRK37742.1 - 1e-11 45.8 0.1 1.9e-11 45.0 0.1 1.4 1 0 0 1 1 1 1 CHRD domain PIG-P PF08510.12 CRK37743.1 - 1.3e-50 170.4 1.9 1.9e-50 169.8 1.9 1.3 1 0 0 1 1 1 1 PIG-P EcKinase PF02958.20 CRK37743.1 - 3.7e-14 52.7 0.0 5.6e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 Ecdysteroid kinase APH PF01636.23 CRK37743.1 - 5e-11 43.0 1.4 8.2e-11 42.3 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CRK37743.1 - 0.049 13.2 0.0 0.076 12.6 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1679 PF07914.11 CRK37743.1 - 0.12 11.3 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) DPM2 PF07297.12 CRK37743.1 - 2.6 8.4 11.0 5.2 7.4 11.0 1.4 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) DUF485 PF04341.12 CRK37743.1 - 7 6.7 8.3 0.15 12.0 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF485 Actin PF00022.19 CRK37744.1 - 7e-144 479.4 0.0 8.2e-144 479.2 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 CRK37744.1 - 0.00012 21.1 0.0 0.28 10.0 0.0 2.5 3 0 0 3 3 3 2 MreB/Mbl protein DUF3591 PF12157.8 CRK37745.1 - 6.3e-147 489.8 3.5 1.5e-120 402.9 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3591) zf-CCHC PF00098.23 CRK37745.1 - 0.004 17.2 1.2 0.0073 16.3 1.2 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 CRK37745.1 - 0.48 10.3 4.0 0.36 10.7 1.7 2.1 2 0 0 2 2 2 0 Zinc knuckle RCR PF12273.8 CRK37746.1 - 2.3e-16 60.5 8.4 2.3e-16 60.5 8.4 2.2 1 1 0 2 2 2 1 Chitin synthesis regulation, resistance to Congo red tRNA-synt_2c PF01411.19 CRK37748.1 - 2e-200 667.0 0.0 2e-200 667.0 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 CRK37748.1 - 6.5e-18 64.6 0.4 1.7e-17 63.2 0.4 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 CRK37748.1 - 4e-10 40.3 1.5 4e-10 40.3 1.5 2.4 2 0 0 2 2 2 1 DHHA1 domain cobW PF02492.19 CRK37748.1 - 0.012 15.2 0.7 0.02 14.5 0.7 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF5370 PF17340.2 CRK37748.1 - 0.041 13.8 0.1 0.12 12.3 0.1 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5370) Peptidase_C11 PF03415.14 CRK37748.1 - 0.075 12.4 0.3 0.16 11.4 0.3 1.5 1 0 0 1 1 1 0 Clostripain family LprI PF07007.12 CRK37748.1 - 1.5 9.5 5.7 5.1 7.8 3.3 2.7 2 1 0 2 2 2 0 Lysozyme inhibitor LprI Methyltransf_28 PF02636.17 CRK37749.1 - 2.4e-41 142.1 0.0 3.5e-41 141.6 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.16 CRK37749.1 - 0.00014 21.7 0.0 0.00027 20.8 0.0 1.4 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase TFIIS_M PF07500.14 CRK37750.1 - 1e-26 93.6 0.7 1e-26 93.6 0.7 1.8 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 CRK37750.1 - 1.1e-18 66.7 6.6 2.1e-18 65.9 6.6 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 CRK37750.1 - 4e-12 46.0 1.1 8.7e-12 44.9 0.7 1.9 2 0 0 2 2 2 1 TFIIS helical bundle-like domain DFRP_C PF16543.5 CRK37750.1 - 0.14 12.7 3.2 1.1 9.8 0.1 2.4 2 0 0 2 2 2 0 DRG Family Regulatory Proteins, Tma46 zf-ZPR1 PF03367.13 CRK37750.1 - 0.42 10.4 5.7 0.33 10.8 0.4 2.8 2 1 1 3 3 3 0 ZPR1 zinc-finger domain MAGUK_N_PEST PF10608.9 CRK37750.1 - 1.5 9.2 5.0 3.2 8.2 0.8 2.3 2 0 0 2 2 2 0 Polyubiquitination (PEST) N-terminal domain of MAGUK CPSF100_C PF13299.6 CRK37750.1 - 6.7 6.9 7.9 3.5 7.8 0.8 2.6 2 1 1 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal zf-RING_2 PF13639.6 CRK37752.1 - 4.3e-12 46.2 6.7 7.9e-12 45.3 6.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CRK37752.1 - 2.1e-08 33.8 5.5 3.9e-08 33.0 5.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CRK37752.1 - 1.1e-07 31.5 5.7 1.1e-07 31.5 5.7 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 CRK37752.1 - 2.2e-06 27.4 5.9 4.1e-06 26.6 5.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CRK37752.1 - 3.1e-06 27.0 5.0 5.6e-06 26.2 5.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CRK37752.1 - 8.8e-06 25.6 2.0 8.8e-06 25.6 2.0 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 CRK37752.1 - 1.4e-05 25.3 3.4 3.7e-05 23.9 3.4 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 CRK37752.1 - 7.9e-05 22.4 5.3 0.00015 21.5 5.3 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 CRK37752.1 - 0.00017 21.4 4.5 0.00029 20.6 4.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CRK37752.1 - 0.0018 18.3 1.1 0.004 17.2 1.1 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 CRK37752.1 - 0.032 13.8 2.8 0.061 13.0 2.8 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Rtf2 PF04641.12 CRK37752.1 - 0.074 12.4 0.1 0.12 11.7 0.1 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger Vps39_2 PF10367.9 CRK37752.1 - 0.08 13.4 1.6 0.2 12.1 0.3 2.1 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 WBP-1 PF11669.8 CRK37752.1 - 0.093 13.4 1.8 0.099 13.3 0.1 2.0 2 0 0 2 2 1 0 WW domain-binding protein 1 zf-C3HC4_4 PF15227.6 CRK37752.1 - 0.16 12.1 6.9 0.33 11.2 6.9 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-HC5HC2H_2 PF13832.6 CRK37752.1 - 0.17 12.1 1.3 0.21 11.8 0.3 1.6 1 1 0 1 1 1 0 PHD-zinc-finger like domain YdjO PF14169.6 CRK37752.1 - 0.29 10.9 2.0 17 5.2 0.2 3.1 2 1 1 3 3 3 0 Cold-inducible protein YdjO zf-RING_4 PF14570.6 CRK37752.1 - 0.43 10.4 3.9 0.78 9.6 3.9 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.7 CRK37752.1 - 0.64 10.2 3.4 1.2 9.3 3.4 1.5 1 0 0 1 1 1 0 RING-variant domain zf-Nse PF11789.8 CRK37752.1 - 1.2 9.0 4.6 2.8 7.9 4.6 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.8 CRK37752.1 - 1.5 9.0 5.1 8.6 6.6 5.1 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.29 CRK37752.1 - 2.7 8.0 4.3 5.9 6.9 4.3 1.6 1 0 0 1 1 1 0 PHD-finger Glyco_hydro_45 PF02015.16 CRK37755.1 - 1.3e-61 208.2 12.9 4.6e-42 144.3 0.5 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 45 Het-C PF07217.11 CRK37756.1 - 5.7e-187 622.7 2.4 3.2e-136 455.2 0.1 2.0 1 1 1 2 2 2 2 Heterokaryon incompatibility protein Het-C Zn_dep_PLPC PF00882.18 CRK37756.1 - 0.0065 16.5 0.0 0.016 15.2 0.0 1.7 1 0 0 1 1 1 1 Zinc dependent phospholipase C HMG_box PF00505.19 CRK37757.1 - 3.7e-07 30.5 0.2 8.6e-07 29.3 0.2 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CRK37757.1 - 0.00019 21.9 0.2 0.00057 20.4 0.2 1.8 1 0 0 1 1 1 1 HMG-box domain CDC45 PF02724.14 CRK37757.1 - 2.5 6.3 6.6 3.1 6.0 6.6 1.2 1 0 0 1 1 1 0 CDC45-like protein XRCC4 PF06632.12 CRK37757.1 - 6.6 5.5 11.9 9.9 4.9 11.9 1.2 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Urease_alpha PF00449.20 CRK37758.1 - 9.2e-56 187.4 0.6 9.2e-56 187.4 0.6 1.9 2 0 0 2 2 2 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.20 CRK37758.1 - 1.8e-40 136.9 0.3 4.5e-40 135.6 0.1 1.8 2 0 0 2 2 2 1 Urease beta subunit Urease_gamma PF00547.18 CRK37758.1 - 5.6e-40 135.7 0.0 1.4e-39 134.3 0.0 1.7 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_1 PF01979.20 CRK37758.1 - 0.066 12.5 0.2 0.12 11.7 0.2 1.4 1 0 0 1 1 1 0 Amidohydrolase family Amelin PF05111.12 CRK37758.1 - 0.12 11.5 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 Ameloblastin precursor (Amelin) HMG_box PF00505.19 CRK37759.1 - 5e-07 30.0 0.2 1.2e-06 28.8 0.2 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CRK37759.1 - 0.00025 21.6 0.2 0.0008 19.9 0.2 1.9 1 0 0 1 1 1 1 HMG-box domain CDC45 PF02724.14 CRK37759.1 - 4.8 5.4 7.0 6.9 4.8 7.0 1.3 1 0 0 1 1 1 0 CDC45-like protein XRCC4 PF06632.12 CRK37759.1 - 9.4 5.0 11.9 15 4.3 11.9 1.3 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Amidohydro_1 PF01979.20 CRK37760.1 - 3.7e-75 253.4 0.2 5.7e-75 252.8 0.2 1.2 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 CRK37760.1 - 1.3e-55 186.9 0.6 1.3e-55 186.9 0.6 1.9 2 0 0 2 2 2 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.20 CRK37760.1 - 1e-40 137.7 0.1 2.4e-40 136.5 0.1 1.6 1 0 0 1 1 1 1 Urease beta subunit Urease_gamma PF00547.18 CRK37760.1 - 3e-39 133.3 0.0 8.4e-39 131.9 0.0 1.8 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_3 PF07969.11 CRK37760.1 - 3.5e-09 36.6 0.3 3.1e-06 26.9 0.0 2.4 1 1 0 2 2 2 2 Amidohydrolase family Amidohydro_2 PF04909.14 CRK37760.1 - 0.11 12.3 0.0 0.32 10.7 0.0 1.8 2 0 0 2 2 2 0 Amidohydrolase DUF3419 PF11899.8 CRK37762.1 - 5.1e-160 532.9 0.0 7e-160 532.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Ada3 PF10198.9 CRK37762.1 - 6.3e-55 184.9 0.9 6.3e-55 184.9 0.9 2.6 3 0 0 3 3 3 1 Histone acetyltransferases subunit 3 Methyltransf_23 PF13489.6 CRK37762.1 - 2.3e-15 56.8 0.0 3e-14 53.2 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK37762.1 - 8.8e-10 39.2 0.4 5.6e-09 36.6 0.0 2.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK37762.1 - 1.7e-08 35.0 0.0 1.2e-06 29.1 0.0 3.1 2 1 0 2 2 1 1 Methyltransferase domain FAD_binding_3 PF01494.19 CRK37762.1 - 5.6e-08 32.4 0.1 0.00017 21.0 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain Methyltransf_11 PF08241.12 CRK37762.1 - 1.6e-06 28.7 0.0 0.00017 22.1 0.0 3.0 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK37762.1 - 2.2e-06 27.5 0.0 6.4e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CRK37762.1 - 4.3e-06 26.2 0.0 0.0068 15.8 0.0 2.3 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family UBA PF00627.31 CRK37762.1 - 0.00052 19.9 0.6 0.0031 17.4 0.4 2.3 2 0 0 2 2 2 1 UBA/TS-N domain PCMT PF01135.19 CRK37762.1 - 0.0028 17.5 0.0 0.0056 16.4 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) YlqD PF11068.8 CRK37762.1 - 0.079 13.3 1.2 4.8 7.6 0.1 2.8 2 0 0 2 2 2 0 YlqD protein DUF1754 PF08555.10 CRK37762.1 - 3.7 8.4 14.9 0.045 14.5 5.5 2.3 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) PRCC PF10253.9 CRK37762.1 - 4.8 7.9 9.3 73 4.0 7.0 2.8 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting IBN_N PF03810.19 CRK37763.1 - 6.5e-10 38.8 0.2 8.2e-09 35.3 0.0 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 CRK37763.1 - 0.00013 22.0 0.0 0.00029 20.9 0.0 1.6 1 0 0 1 1 1 1 Exportin 1-like protein FAD_binding_3 PF01494.19 CRK37764.1 - 3.5e-07 29.8 0.1 0.00012 21.5 0.1 2.4 2 0 0 2 2 2 2 FAD binding domain DUF885 PF05960.11 CRK37764.1 - 0.055 13.1 0.2 0.78 9.3 0.0 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF885) SOBP PF15279.6 CRK37764.1 - 9.1 6.8 11.5 0.65 10.6 4.2 2.3 2 0 0 2 2 2 0 Sine oculis-binding protein DNA_pol_phi PF04931.13 CRK37764.1 - 9.2 4.2 9.6 18 3.3 9.6 1.3 1 0 0 1 1 1 0 DNA polymerase phi DUF3419 PF11899.8 CRK37765.1 - 1.3e-160 534.9 0.0 1.6e-160 534.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.6 CRK37765.1 - 9.1e-16 58.1 0.0 1.1e-14 54.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK37765.1 - 4e-10 40.3 0.0 2.1e-09 38.0 0.0 2.3 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK37765.1 - 2.2e-09 37.9 0.0 4.9e-07 30.4 0.0 3.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CRK37765.1 - 2.4e-07 31.3 0.0 7.2e-05 23.4 0.0 3.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK37765.1 - 7.6e-07 29.0 0.0 2.3e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CRK37765.1 - 1.2e-06 28.1 0.0 0.0047 16.3 0.0 2.4 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family UBA PF00627.31 CRK37765.1 - 3.9e-05 23.4 0.2 9.8e-05 22.2 0.2 1.7 1 0 0 1 1 1 1 UBA/TS-N domain PCMT PF01135.19 CRK37765.1 - 0.00082 19.2 0.0 0.0017 18.1 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NAD_binding_8 PF13450.6 CRK37765.1 - 0.0042 17.3 0.6 0.014 15.6 0.6 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 CRK37765.1 - 0.21 10.8 0.5 0.37 10.0 0.5 1.3 1 0 0 1 1 1 0 FAD binding domain IBN_N PF03810.19 CRK37766.1 - 3.8e-10 39.5 0.5 3.7e-09 36.4 0.0 2.8 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.12 CRK37766.1 - 6.5e-07 29.5 0.0 0.00039 20.5 0.0 2.8 2 0 0 2 2 2 2 Exportin 1-like protein NUC173 PF08161.12 CRK37766.1 - 0.12 12.0 0.3 2.5 7.7 0.2 2.4 2 0 0 2 2 2 0 NUC173 domain ADH_zinc_N PF00107.26 CRK37768.1 - 1.9e-31 108.8 0.5 2.9e-31 108.2 0.5 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CRK37768.1 - 9.3e-10 39.7 0.0 1.7e-09 38.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CRK37768.1 - 4.7e-06 26.5 0.0 1.7e-05 24.7 0.0 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 CRK37768.1 - 0.01 16.1 0.1 0.016 15.4 0.1 1.3 1 0 0 1 1 1 0 TrkA-N domain AlaDh_PNT_C PF01262.21 CRK37768.1 - 0.1 11.9 3.4 0.14 11.4 3.0 1.4 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ADH_N PF08240.12 CRK37769.1 - 1.1e-06 28.5 0.0 4.8e-06 26.4 0.0 1.9 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ubiquitin PF00240.23 CRK37770.1 - 4.4e-18 64.8 0.0 6.2e-18 64.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 CRK37770.1 - 1.2e-06 28.2 1.2 3.6e-06 26.8 0.0 2.3 2 0 0 2 2 2 1 UBA/TS-N domain Rad60-SLD PF11976.8 CRK37770.1 - 0.00018 21.3 0.0 0.00029 20.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 CRK37770.1 - 0.00085 19.9 0.0 0.0015 19.1 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 CRK37770.1 - 0.0014 18.7 0.0 0.0024 18.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like HOIP-UBA PF16678.5 CRK37770.1 - 0.11 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 HOIP UBA domain pair NPR2 PF06218.11 CRK37771.1 - 8.9e-60 202.7 0.1 1.3e-59 202.1 0.1 1.3 1 0 0 1 1 1 1 Nitrogen permease regulator 2 UBA PF00627.31 CRK37771.1 - 2.3e-06 27.4 1.5 4.1e-06 26.6 0.1 2.2 2 0 0 2 2 2 1 UBA/TS-N domain GET2 PF08690.10 CRK37771.1 - 0.073 12.7 0.7 0.15 11.7 0.7 1.5 1 0 0 1 1 1 0 GET complex subunit GET2 HOIP-UBA PF16678.5 CRK37771.1 - 0.091 12.8 0.0 0.3 11.1 0.0 1.9 1 0 0 1 1 1 0 HOIP UBA domain pair SNAP PF14938.6 CRK37771.1 - 0.24 10.8 0.0 0.39 10.1 0.0 1.2 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP NPR2 PF06218.11 CRK37773.1 - 9.6e-118 393.7 0.0 2.2e-98 329.9 0.0 2.0 1 1 1 2 2 2 2 Nitrogen permease regulator 2 tRNA-synt_1b PF00579.25 CRK37774.1 - 7.1e-77 258.6 0.0 9.6e-77 258.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TyrRSs_C PF16714.5 CRK37774.1 - 4.6e-48 162.0 0.0 9.5e-48 161.0 0.0 1.6 1 0 0 1 1 1 1 Tyrosyl-tRNA synthetase C-terminal domain AAA_30 PF13604.6 CRK37774.1 - 0.0012 18.6 1.4 0.033 13.9 0.2 2.4 2 0 0 2 2 2 1 AAA domain Milton PF12448.8 CRK37774.1 - 0.01 15.9 0.0 0.023 14.8 0.0 1.5 1 0 0 1 1 1 0 Kinesin associated protein APT PF03440.14 CRK37774.1 - 0.26 11.3 0.7 31 4.6 0.0 2.9 2 1 0 2 2 2 0 Aerolysin/Pertussis toxin (APT) domain CybS PF05328.12 CRK37775.1 - 1.6e-33 115.2 0.0 2.3e-33 114.7 0.0 1.2 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit tRNA-synt_1b PF00579.25 CRK37776.1 - 6.7e-76 255.4 0.0 8.9e-76 255.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TyrRSs_C PF16714.5 CRK37776.1 - 5.5e-38 129.5 0.0 1.2e-37 128.3 0.0 1.6 1 0 0 1 1 1 1 Tyrosyl-tRNA synthetase C-terminal domain AAA_30 PF13604.6 CRK37776.1 - 0.0097 15.6 4.6 0.034 13.9 0.3 2.6 3 0 0 3 3 3 1 AAA domain Milton PF12448.8 CRK37776.1 - 0.012 15.8 0.0 0.022 14.9 0.0 1.3 1 0 0 1 1 1 0 Kinesin associated protein CybS PF05328.12 CRK37777.1 - 2.6e-49 166.3 0.0 3.5e-49 165.9 0.0 1.2 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit Pex2_Pex12 PF04757.14 CRK37778.1 - 1.2e-37 129.7 0.7 1.7e-37 129.2 0.7 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.6 CRK37778.1 - 0.0014 18.8 4.0 0.0028 17.8 4.0 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 CRK37778.1 - 0.0033 17.4 0.8 0.0088 16.1 0.8 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CRK37778.1 - 0.14 12.1 2.4 0.3 11.0 2.4 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CRK37778.1 - 0.18 11.7 4.3 0.094 12.6 0.8 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) CybS PF05328.12 CRK37779.1 - 2.4e-27 95.2 0.0 2.8e-27 95.0 0.0 1.0 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit Pex2_Pex12 PF04757.14 CRK37780.1 - 5.2e-37 127.6 0.9 7.4e-37 127.1 0.9 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.6 CRK37780.1 - 0.0014 18.8 4.0 0.0028 17.8 4.0 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 CRK37780.1 - 0.0032 17.5 0.8 0.0087 16.1 0.8 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CRK37780.1 - 0.14 12.0 4.1 0.093 12.6 0.8 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CRK37780.1 - 0.15 12.0 2.6 0.34 10.8 2.6 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) SprT-like PF10263.9 CRK37782.1 - 8.4e-11 41.7 0.0 8.4e-11 41.7 0.0 1.6 2 0 0 2 2 2 1 SprT-like family DUF3846 PF12957.7 CRK37782.1 - 0.15 12.4 0.0 0.86 10.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3846) ATE_C PF04377.15 CRK37783.1 - 4.7e-28 98.5 0.0 7.8e-28 97.8 0.0 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus DUF4875 PF16175.5 CRK37783.1 - 0.16 12.1 0.0 0.26 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4875) RNase_PH PF01138.21 CRK37784.1 - 9.9e-13 48.7 0.0 2e-12 47.7 0.0 1.5 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CRK37784.1 - 0.0079 16.2 0.0 0.015 15.3 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Cytochrom_C PF00034.21 CRK37786.1 - 2.4e-12 47.8 0.1 3.1e-12 47.5 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 CRK37786.1 - 5e-09 36.4 2.6 1.5e-08 34.8 2.6 1.7 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 CRK37786.1 - 0.0062 16.2 0.5 0.054 13.2 0.1 2.2 2 1 0 2 2 2 1 Cytochrome c-550 domain AAA PF00004.29 CRK37787.1 - 1.4e-54 184.1 0.0 6.9e-45 152.7 0.0 2.9 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CRK37787.1 - 1e-12 47.6 0.2 7.4e-07 28.9 0.1 2.6 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 CRK37787.1 - 6.7e-11 42.9 0.5 0.0011 19.4 0.0 4.7 3 2 1 4 4 4 2 AAA ATPase domain AAA_5 PF07728.14 CRK37787.1 - 4.8e-06 26.6 0.1 0.0081 16.2 0.0 3.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CRK37787.1 - 9.7e-06 25.9 0.0 0.011 16.0 0.0 3.8 2 1 1 3 3 3 1 AAA domain RuvB_N PF05496.12 CRK37787.1 - 1.6e-05 24.7 0.0 0.00041 20.1 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 CRK37787.1 - 0.00011 22.4 0.0 0.0011 19.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Rad17 PF03215.15 CRK37787.1 - 0.00012 22.1 0.0 0.13 12.1 0.0 2.5 2 1 0 2 2 2 2 Rad17 P-loop domain AAA_33 PF13671.6 CRK37787.1 - 0.00032 20.9 0.0 0.0083 16.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 CRK37787.1 - 0.00033 20.9 0.1 0.7 10.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 CRK37787.1 - 0.0005 20.4 0.0 0.048 14.1 0.0 2.6 2 0 0 2 2 2 1 RNA helicase Zeta_toxin PF06414.12 CRK37787.1 - 0.00053 19.3 0.5 0.044 13.1 0.0 2.9 3 0 0 3 3 3 1 Zeta toxin AAA_18 PF13238.6 CRK37787.1 - 0.00057 20.4 0.5 0.36 11.4 0.0 3.1 3 0 0 3 3 3 1 AAA domain Sigma54_activ_2 PF14532.6 CRK37787.1 - 0.002 18.3 0.0 0.043 13.9 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 CRK37787.1 - 0.0026 17.2 0.2 0.073 12.4 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 CRK37787.1 - 0.0033 17.2 0.0 0.043 13.6 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_11 PF13086.6 CRK37787.1 - 0.0053 16.6 3.3 2.8 7.7 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_14 PF13173.6 CRK37787.1 - 0.0062 16.6 0.0 0.071 13.1 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.6 CRK37787.1 - 0.0066 16.0 0.0 5 6.7 0.0 3.3 3 0 0 3 3 3 1 AAA domain Sigma54_activat PF00158.26 CRK37787.1 - 0.019 14.7 0.0 0.6 9.8 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_17 PF13207.6 CRK37787.1 - 0.026 14.9 0.4 2.5 8.5 0.0 3.0 3 0 0 3 3 2 0 AAA domain DUF815 PF05673.13 CRK37787.1 - 0.036 13.2 0.0 0.43 9.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_30 PF13604.6 CRK37787.1 - 0.041 13.6 0.1 11 5.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 CRK37787.1 - 0.041 14.4 0.3 2.9 8.4 0.0 3.2 3 1 0 3 3 2 0 ABC transporter Viral_helicase1 PF01443.18 CRK37787.1 - 0.045 13.5 0.0 1.7 8.3 0.0 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_7 PF12775.7 CRK37787.1 - 0.057 12.9 0.0 1 8.9 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region TIP49 PF06068.13 CRK37787.1 - 0.12 11.6 0.1 0.31 10.2 0.0 1.7 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_19 PF13245.6 CRK37787.1 - 0.12 12.7 0.2 8 6.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 CRK37787.1 - 0.15 11.7 0.1 3 7.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 CRK37787.1 - 0.15 11.4 0.0 1.2 8.5 0.0 2.4 3 0 0 3 3 3 0 Bacterial TniB protein AAA_3 PF07726.11 CRK37787.1 - 0.18 11.7 0.0 2.4 8.0 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Snf7 PF03357.21 CRK37788.1 - 8.1e-27 93.9 11.0 1.2e-26 93.4 11.0 1.2 1 0 0 1 1 1 1 Snf7 DUF2293 PF10056.9 CRK37789.1 - 2.4e-28 98.2 0.1 6.6e-28 96.8 0.1 1.8 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) Mito_carr PF00153.27 CRK37790.1 - 4.2e-25 87.5 3.1 5.6e-15 55.0 0.3 3.2 2 1 0 2 2 2 2 Mitochondrial carrier protein Mito_carr PF00153.27 CRK37791.1 - 8.4e-12 44.9 0.0 1.3e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial carrier protein LysM PF01476.20 CRK37792.1 - 1.8e-06 27.9 6.6 1 9.5 0.0 4.8 6 0 0 6 6 6 3 LysM domain Rubella_E2 PF05749.11 CRK37792.1 - 0.016 14.7 0.8 0.016 14.7 0.8 3.3 3 0 0 3 3 3 0 Rubella membrane glycoprotein E2 Slx4 PF09494.10 CRK37792.1 - 0.022 14.7 0.0 22 5.1 0.0 3.2 3 0 0 3 3 3 0 Slx4 endonuclease HSDR_N_2 PF13588.6 CRK37792.1 - 0.049 13.6 0.0 1.1 9.3 0.0 2.5 3 0 0 3 3 3 0 Type I restriction enzyme R protein N terminus (HSDR_N) DUF5503 PF17607.2 CRK37792.1 - 0.11 12.8 0.0 23 5.3 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5503) UPF0203 PF05254.12 CRK37792.1 - 0.14 12.4 2.7 22 5.4 0.1 3.4 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0203) Ribosomal_L3 PF00297.22 CRK37795.1 - 4.1e-16 58.9 3.2 7e-13 48.3 1.5 2.2 1 1 1 2 2 2 2 Ribosomal protein L3 Coa1 PF08695.10 CRK37796.1 - 6.5e-43 145.2 0.0 9.3e-43 144.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 DUF3267 PF11667.8 CRK37797.1 - 0.71 10.2 3.9 0.28 11.5 0.5 1.9 2 0 0 2 2 2 0 Putative zincin peptidase PGF-CTERM PF18204.1 CRK37797.1 - 5.7 7.0 8.0 3.9 7.6 1.4 2.8 2 0 0 2 2 2 0 PGF-CTERM motif Ank_2 PF12796.7 CRK37798.1 - 4.4e-33 113.7 1.4 7.9e-10 39.2 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CRK37798.1 - 6.8e-33 112.6 6.9 1e-09 38.7 0.1 6.5 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 CRK37798.1 - 6.2e-22 75.3 4.8 0.0011 19.2 0.0 7.0 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 CRK37798.1 - 2.8e-20 72.1 7.1 0.00026 21.2 0.0 6.7 2 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 CRK37798.1 - 3.5e-17 62.0 14.6 0.0024 18.2 0.0 8.3 7 1 1 8 8 8 4 Ankyrin repeat GDPD PF03009.17 CRK37798.1 - 2.3e-07 30.8 0.0 7e-07 29.2 0.0 1.7 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family RVP PF00077.20 CRK37798.1 - 0.00092 19.5 0.0 0.0022 18.3 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease SKG6 PF08693.10 CRK37801.1 - 4.1e-10 38.9 5.2 8.8e-10 37.8 5.2 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain CD34_antigen PF06365.12 CRK37801.1 - 0.009 15.6 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 CD34/Podocalyxin family CDC27 PF09507.10 CRK37801.1 - 2.9 7.2 15.9 5.4 6.3 15.9 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Ndc1_Nup PF09531.10 CRK37801.1 - 9.5 4.8 8.3 13 4.3 8.3 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Hist_deacetyl PF00850.19 CRK37802.1 - 1.8e-79 267.4 0.0 2.6e-79 266.9 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.9 CRK37802.1 - 5e-77 258.5 0.0 8.6e-77 257.8 0.0 1.3 1 0 0 1 1 1 1 Arb2 domain adh_short PF00106.25 CRK37802.1 - 4.2e-36 124.3 0.2 7.6e-36 123.4 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK37802.1 - 2.4e-32 112.4 0.1 4.6e-32 111.4 0.1 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK37802.1 - 1.7e-07 31.4 0.3 2.9e-07 30.6 0.3 1.3 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 CRK37802.1 - 0.0066 16.7 0.6 0.015 15.5 0.2 1.9 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 CRK37802.1 - 0.02 14.8 0.1 0.04 13.8 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H-binding ADH_zinc_N PF00107.26 CRK37802.1 - 0.025 14.5 0.2 0.05 13.6 0.2 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Epimerase PF01370.21 CRK37802.1 - 0.042 13.3 0.1 0.095 12.1 0.1 1.6 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CRK37802.1 - 0.088 11.8 0.1 0.13 11.2 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 CRK37802.1 - 0.22 10.9 0.0 0.46 9.8 0.0 1.5 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase F-box-like PF12937.7 CRK37803.1 - 0.17 11.8 2.3 0.25 11.3 0.0 2.4 3 0 0 3 3 3 0 F-box-like Ras PF00071.22 CRK37804.1 - 1.3e-62 210.2 0.1 1.5e-62 209.9 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CRK37804.1 - 3.2e-34 117.7 0.1 4.4e-34 117.3 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CRK37804.1 - 1.5e-12 47.4 0.1 1.9e-12 47.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CRK37804.1 - 4.2e-07 30.0 0.1 6.5e-07 29.4 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CRK37804.1 - 4.7e-05 23.4 0.1 0.005 16.8 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 CRK37804.1 - 0.00012 22.4 0.0 0.00066 20.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 CRK37804.1 - 0.00042 19.9 0.1 0.0012 18.4 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CRK37804.1 - 0.0024 17.3 0.1 0.0037 16.7 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_14 PF13173.6 CRK37804.1 - 0.0039 17.2 0.1 0.01 15.9 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CRK37804.1 - 0.0042 17.5 0.1 0.0072 16.7 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 CRK37804.1 - 0.015 14.7 0.0 0.026 14.0 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 CRK37804.1 - 0.019 15.5 0.1 0.027 15.0 0.1 1.4 1 1 0 1 1 1 0 ABC transporter TniB PF05621.11 CRK37804.1 - 0.025 14.0 0.0 0.12 11.8 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein AAA_24 PF13479.6 CRK37804.1 - 0.072 12.8 0.1 0.14 11.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_21 PF13304.6 CRK37804.1 - 0.077 12.8 0.7 0.13 12.1 0.6 1.5 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system SpoIIID PF12116.8 CRK37804.1 - 0.12 12.5 0.1 2.1 8.5 0.0 2.2 2 0 0 2 2 2 0 Stage III sporulation protein D Lectin_leg-like PF03388.13 CRK37806.1 - 8.5e-33 113.6 0.0 1e-32 113.4 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 CRK37806.1 - 0.006 16.6 0.3 0.007 16.4 0.3 1.1 1 0 0 1 1 1 1 Bacterial lectin Nic96 PF04097.14 CRK37838.1 - 7.2e-20 71.0 0.0 7.8e-20 70.9 0.0 1.0 1 0 0 1 1 1 1 Nup93/Nic96 UPF0220 PF05255.11 CRK37840.1 - 6.2e-35 120.2 1.2 6.8e-35 120.1 1.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DUF5337 PF17272.2 CRK37840.1 - 0.057 13.3 0.2 0.081 12.8 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5337) Hid1 PF12722.7 CRK37843.1 - 8.8e-29 100.2 0.4 1.2e-28 99.8 0.4 1.1 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein MFS_1 PF07690.16 CRK37843.1 - 6.6e-20 71.3 17.7 1.1e-19 70.5 17.7 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK37843.1 - 3.2e-07 29.6 6.8 3.2e-07 29.6 6.8 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 CRK37843.1 - 0.0003 19.3 7.1 0.00041 18.9 7.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Globin PF00042.22 CRK37844.1 - 6e-05 23.6 0.0 6.9e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Globin Protoglobin PF11563.8 CRK37844.1 - 0.0067 16.3 0.0 0.0072 16.2 0.0 1.1 1 0 0 1 1 1 1 Protoglobin Tox-HNH-HHH PF15637.6 CRK37844.1 - 0.086 13.0 0.0 0.1 12.8 0.0 1.1 1 0 0 1 1 1 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif DIOX_N PF14226.6 CRK37849.1 - 3.2e-07 31.1 0.0 3.6e-07 30.9 0.0 1.0 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Nop PF01798.18 CRK37850.1 - 7.3e-27 94.3 0.0 8.1e-27 94.2 0.0 1.0 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin DUF1690 PF07956.11 CRK37853.1 - 1.3e-22 80.7 0.9 1.5e-22 80.5 0.9 1.0 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) Lebercilin PF15619.6 CRK37853.1 - 0.0033 17.1 0.1 0.0035 17.0 0.1 1.0 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease CAMSAP_CC1 PF17095.5 CRK37853.1 - 0.018 14.9 0.8 0.038 13.8 0.8 1.6 1 0 0 1 1 1 0 Spectrin-binding region of Ca2+-Calmodulin Rootletin PF15035.6 CRK37853.1 - 0.019 15.0 1.4 0.026 14.5 1.4 1.1 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion CBM64 PF18666.1 CRK37860.1 - 0.037 14.1 0.5 0.059 13.5 0.5 1.5 1 1 0 1 1 1 0 Carbohydrate-binding module 64 ABC_membrane PF00664.23 CRK37861.1 - 7.4e-10 38.9 0.4 7.4e-10 38.9 0.4 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region Vps39_2 PF10367.9 CRK37874.1 - 2.8e-06 27.8 0.0 5.3e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.20 CRK37874.1 - 0.064 13.1 0.0 0.47 10.3 0.0 2.2 2 0 0 2 2 2 0 Region in Clathrin and VPS zf-C2H2 PF00096.26 CRK37875.1 - 5.8e-05 23.3 19.0 0.32 11.6 1.2 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type Plus-3 PF03126.18 CRK37875.1 - 0.0016 19.0 0.0 1.5 9.3 0.0 2.4 2 0 0 2 2 2 2 Plus-3 domain DUF2309 PF10070.9 CRK37875.1 - 0.05 11.9 1.2 3.2 6.0 0.2 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2309) zf-C2H2_4 PF13894.6 CRK37875.1 - 0.12 13.3 19.5 0.57 11.2 0.7 4.8 4 1 0 4 4 4 0 C2H2-type zinc finger CENP-B_dimeris PF09026.10 CRK37875.1 - 0.21 12.0 17.1 1.5 9.3 3.6 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain zf-TAZ PF02135.16 CRK37875.1 - 0.28 11.7 4.2 0.36 11.3 1.7 2.2 2 0 0 2 2 2 0 TAZ zinc finger zf-C2HE PF16278.5 CRK37875.1 - 1.1 9.8 3.3 12 6.4 0.4 3.1 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger RXT2_N PF08595.11 CRK37875.1 - 1.2 9.2 18.5 3.9 7.5 5.4 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal CMD PF02627.20 CRK37878.1 - 0.0012 18.8 0.0 0.0025 17.8 0.0 1.5 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family zf-rbx1 PF12678.7 CRK37879.1 - 5.4e-10 39.4 4.2 1e-09 38.5 4.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CRK37879.1 - 1.2e-08 35.1 4.8 2.4e-08 34.2 4.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 CRK37879.1 - 4.4e-06 26.7 0.9 8.2e-06 25.8 0.9 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 CRK37879.1 - 9.6e-06 25.5 2.2 1.9e-05 24.6 2.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CRK37879.1 - 2.1e-05 24.3 3.1 3.8e-05 23.5 3.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CRK37879.1 - 4.6e-05 23.3 2.2 0.00015 21.6 2.4 1.8 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CRK37879.1 - 0.00027 20.7 6.2 0.0015 18.3 2.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CRK37879.1 - 0.00061 19.4 0.6 0.0013 18.3 0.6 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 CRK37879.1 - 0.0011 18.7 2.8 0.0011 18.7 2.8 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CRK37879.1 - 0.0019 18.0 4.2 0.0058 16.5 4.3 1.7 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 CRK37879.1 - 0.14 12.4 1.2 0.3 11.3 1.2 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF1409 PF07197.12 CRK37879.1 - 0.17 11.8 0.1 0.36 10.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1409) zf-RING_11 PF17123.5 CRK37879.1 - 0.42 10.4 1.5 3.3 7.5 1.5 2.2 1 1 0 1 1 1 0 RING-like zinc finger zf-RING_4 PF14570.6 CRK37879.1 - 1.2 9.0 3.4 0.64 9.8 0.9 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Adaptin_N PF01602.20 CRK37880.1 - 2.8e-141 471.6 2.1 3.9e-141 471.2 2.1 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Glyco_transf_8 PF01501.20 CRK37880.1 - 2.1e-21 76.6 0.3 2.8e-20 73.0 0.3 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 8 Alpha_adaptinC2 PF02883.20 CRK37880.1 - 2.8e-16 59.8 0.1 7.6e-16 58.4 0.1 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 CRK37880.1 - 2e-07 31.2 5.8 3.7e-05 23.8 0.0 3.7 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CRK37880.1 - 0.025 15.0 4.6 4.3 7.8 0.1 3.9 3 1 1 4 4 4 0 HEAT repeats NAD_binding_6 PF08030.12 CRK37880.1 - 0.099 12.8 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 Ferric reductase NAD binding domain Mannosyl_trans3 PF11051.8 CRK37880.1 - 0.13 11.6 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Mannosyltransferase putative HEAT PF02985.22 CRK37880.1 - 0.27 11.6 2.3 16 6.1 0.1 3.9 4 0 0 4 4 4 0 HEAT repeat Ndufs5 PF10200.9 CRK37881.1 - 0.001 19.3 0.0 0.0015 18.8 0.0 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3128 PF11326.8 CRK37881.1 - 0.076 13.4 1.2 0.38 11.2 1.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) COX6B PF02297.17 CRK37881.1 - 0.11 12.7 0.3 0.2 11.9 0.3 1.4 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb SNARE PF05739.19 CRK37883.1 - 5.5e-16 58.3 0.8 1.2e-15 57.2 0.8 1.6 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 CRK37883.1 - 0.0014 18.4 6.6 0.0094 15.6 6.6 2.0 1 1 0 1 1 1 1 Syntaxin MCPsignal PF00015.21 CRK37883.1 - 0.0021 17.9 4.4 0.17 11.7 1.3 2.1 2 0 0 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain Rrp44_CSD1 PF17216.3 CRK37883.1 - 0.11 12.2 0.8 0.21 11.3 0.5 1.6 1 1 0 1 1 1 0 Rrp44-like cold shock domain UBA_5 PF16577.5 CRK37883.1 - 0.13 12.4 0.0 1.2 9.3 0.0 2.3 2 0 0 2 2 2 0 UBA domain CALCOCO1 PF07888.11 CRK37883.1 - 0.21 10.4 2.4 1.8 7.3 0.4 2.0 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like SlyX PF04102.12 CRK37883.1 - 3.1 8.5 5.0 1.9 9.1 0.3 2.6 2 1 1 3 3 3 0 SlyX COX7a PF02238.15 CRK37884.1 - 1e-19 70.7 0.6 1.2e-19 70.4 0.6 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII TspO_MBR PF03073.15 CRK37884.1 - 0.076 13.1 0.1 0.088 12.9 0.1 1.1 1 0 0 1 1 1 0 TspO/MBR family Clathrin_lg_ch PF01086.17 CRK37885.1 - 5e-80 268.9 8.8 5.6e-80 268.7 8.8 1.0 1 0 0 1 1 1 1 Clathrin light chain Lipoprotein_8 PF02030.15 CRK37885.1 - 0.041 12.6 1.9 0.051 12.3 1.9 1.1 1 0 0 1 1 1 0 Hypothetical lipoprotein (MG045 family) Hydrolase_4 PF12146.8 CRK37886.1 - 9e-48 162.6 0.0 1.8e-47 161.7 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 ABC_membrane PF00664.23 CRK37886.1 - 9.6e-46 156.6 5.1 1.4e-45 156.1 5.1 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region CTD_bind PF04818.13 CRK37886.1 - 1.1e-15 58.2 0.0 2.4e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. Abhydrolase_6 PF12697.7 CRK37886.1 - 1.7e-14 54.9 2.8 4.6e-14 53.6 2.8 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CRK37886.1 - 5.6e-10 39.3 0.1 8.9e-09 35.4 0.1 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold CREPT PF16566.5 CRK37886.1 - 0.0027 17.9 0.5 0.0094 16.1 0.5 1.9 1 0 0 1 1 1 1 Cell-cycle alteration and expression-elevated protein in tumour Enkurin PF13864.6 CRK37886.1 - 0.046 14.2 2.6 0.22 12.0 0.1 2.7 2 0 0 2 2 2 0 Calmodulin-binding WD40 PF00400.32 CRK37887.1 - 2.5e-20 72.4 15.8 0.00059 20.6 0.0 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK37887.1 - 1.4e-13 50.9 6.2 4.2e-05 23.8 0.5 4.3 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CRK37887.1 - 6.6e-07 29.4 0.1 0.0027 17.6 0.0 2.8 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A PAS_9 PF13426.7 CRK37888.1 - 5.2e-14 52.4 0.0 2.6e-13 50.1 0.0 2.1 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 CRK37888.1 - 0.014 15.4 0.0 0.047 13.7 0.0 1.9 2 0 0 2 2 2 0 PAS fold STAG PF08514.11 CRK37889.1 - 0.029 14.3 0.2 0.11 12.5 0.2 1.8 1 1 0 1 1 1 0 STAG domain Zw10 PF06248.13 CRK37889.1 - 0.19 10.3 0.1 0.27 9.7 0.1 1.1 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 VPS28 PF03997.12 CRK37889.1 - 0.4 10.3 2.4 0.4 10.3 0.9 1.7 1 1 1 2 2 2 0 VPS28 protein ATG16 PF08614.11 CRK37889.1 - 0.42 10.8 4.3 0.61 10.3 3.1 1.7 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Acetyltransf_1 PF00583.25 CRK37890.1 - 5.8e-14 52.3 0.0 8e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CRK37890.1 - 2.3e-09 37.3 0.0 3.4e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CRK37890.1 - 1.5e-08 34.9 0.0 2.1e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CRK37890.1 - 1e-05 25.4 0.0 1.6e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 CRK37890.1 - 0.013 15.6 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 CRK37890.1 - 0.14 12.3 0.1 0.45 10.6 0.1 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain adh_short_C2 PF13561.6 CRK37891.1 - 4e-58 196.7 0.3 4.7e-58 196.5 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRK37891.1 - 4.9e-46 156.7 1.3 5.6e-46 156.5 1.3 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CRK37891.1 - 1.3e-10 41.5 0.6 1.7e-10 41.1 0.6 1.2 1 0 0 1 1 1 1 KR domain DUF2838 PF10998.8 CRK37892.1 - 0.00012 22.3 0.4 0.00012 22.3 0.4 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF2838) BBP1_C PF15272.6 CRK37892.1 - 0.058 13.2 1.1 0.096 12.5 1.1 1.2 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal DHR10 PF18595.1 CRK37892.1 - 0.32 11.0 2.8 0.77 9.8 2.8 1.5 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain SMC_N PF02463.19 CRK37893.1 - 2e-53 181.1 0.0 1.2e-52 178.5 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CRK37893.1 - 1.5e-24 86.6 0.0 5.3e-24 84.8 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 CRK37893.1 - 1.1e-11 45.1 10.9 8.4e-05 22.5 2.1 4.1 3 1 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CRK37893.1 - 5.5e-08 32.4 0.0 1.2e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 CRK37893.1 - 6.1e-08 32.8 19.7 6.1e-08 32.8 19.7 3.2 2 1 0 2 2 1 1 AAA ATPase domain AAA_23 PF13476.6 CRK37893.1 - 8.3e-08 33.0 21.9 8.3e-08 33.0 21.9 5.7 3 2 1 4 4 3 1 AAA domain MscS_porin PF12795.7 CRK37893.1 - 0.00024 20.7 22.0 0.00024 20.7 22.0 5.4 4 2 1 5 5 5 2 Mechanosensitive ion channel porin domain DUF3584 PF12128.8 CRK37893.1 - 0.00046 17.9 38.8 0.00046 17.9 38.8 4.7 3 1 1 4 4 4 3 Protein of unknown function (DUF3584) Spc7 PF08317.11 CRK37893.1 - 0.0017 17.3 94.8 0.03 13.2 19.3 6.2 3 2 3 6 6 6 3 Spc7 kinetochore protein ATG16 PF08614.11 CRK37893.1 - 0.0024 18.1 92.6 0.0048 17.1 17.0 5.8 4 1 1 5 5 5 2 Autophagy protein 16 (ATG16) FlxA PF14282.6 CRK37893.1 - 0.0046 16.9 0.6 0.0046 16.9 0.6 6.8 4 2 2 7 7 5 2 FlxA-like protein HMMR_N PF15905.5 CRK37893.1 - 0.048 13.1 86.7 0.045 13.2 1.2 5.2 4 1 1 5 5 5 0 Hyaluronan mediated motility receptor N-terminal DUF4988 PF16378.5 CRK37893.1 - 1.1 8.9 16.7 1.1 9.0 0.2 4.4 5 0 0 5 5 5 0 Domain of unknown function Fez1 PF06818.15 CRK37893.1 - 1.3 9.4 90.5 0.12 12.8 16.2 5.5 3 2 1 5 5 5 0 Fez1 Tropomyosin PF00261.20 CRK37893.1 - 2.1 7.7 103.8 0.11 11.9 5.1 6.3 3 2 2 6 6 6 0 Tropomyosin Exonuc_VII_L PF02601.15 CRK37893.1 - 2.3 7.7 73.5 0.29 10.6 14.2 5.1 3 2 2 5 5 5 0 Exonuclease VII, large subunit Mating_N PF12731.7 CRK37893.1 - 3.9 7.6 8.3 0.81 9.8 0.1 4.0 5 0 0 5 5 5 0 Mating-type protein beta 1 Laminin_II PF06009.12 CRK37893.1 - 6.3 6.8 57.9 0.11 12.4 4.9 7.4 5 4 1 6 6 6 0 Laminin Domain II ERM PF00769.19 CRK37893.1 - 7.3 6.3 95.4 0.011 15.6 23.8 4.6 3 2 0 4 4 4 0 Ezrin/radixin/moesin family Aldedh PF00171.22 CRK37894.1 - 3e-164 546.9 0.4 3.4e-164 546.8 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Aminotran_3 PF00202.21 CRK37895.1 - 2.3e-116 388.8 0.0 2.6e-116 388.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Peptidase_M14 PF00246.24 CRK37896.1 - 2e-73 247.7 0.0 2.4e-73 247.4 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase HNH_3 PF13392.6 CRK37896.1 - 0.11 12.3 0.1 8.1 6.3 0.0 2.7 2 0 0 2 2 2 0 HNH endonuclease PH PF00169.29 CRK37898.1 - 4.2e-07 30.4 0.1 9.3e-07 29.3 0.1 1.6 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 CRK37898.1 - 0.00021 21.6 0.3 0.00044 20.6 0.3 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain Osmo_CC PF08946.10 CRK37898.1 - 0.16 12.3 7.5 0.17 12.2 4.2 2.7 2 0 0 2 2 2 0 Osmosensory transporter coiled coil SRP_TPR_like PF17004.5 CRK37900.1 - 9.2e-26 90.2 1.5 2.5e-23 82.3 0.5 2.6 2 0 0 2 2 2 2 Putative TPR-like repeat SRP72 PF08492.12 CRK37900.1 - 1.8e-15 57.1 9.1 1.8e-15 57.1 9.1 2.7 2 0 0 2 2 2 1 SRP72 RNA-binding domain ANAPC3 PF12895.7 CRK37900.1 - 0.0001 22.4 9.7 0.024 14.9 1.0 4.8 4 1 1 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 CRK37900.1 - 0.00013 21.8 21.3 2.1 8.7 0.1 7.6 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.6 CRK37900.1 - 0.022 15.3 28.7 3.9 8.1 0.9 6.4 4 2 2 6 6 6 0 Tetratricopeptide repeat PPR PF01535.20 CRK37900.1 - 0.034 14.4 0.7 11 6.5 0.0 4.8 6 0 0 6 6 5 0 PPR repeat Arg_decarbox_C PF17944.1 CRK37900.1 - 0.95 10.1 2.8 46 4.7 0.3 3.0 2 0 0 2 2 2 0 Arginine decarboxylase C-terminal helical extension TPR_7 PF13176.6 CRK37900.1 - 1.3 9.2 16.2 0.36 11.0 0.2 5.4 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 CRK37900.1 - 1.7 9.4 33.1 0.043 14.5 2.8 5.7 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 CRK37900.1 - 2.1 8.8 4.1 17 5.9 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 CRK37900.1 - 4.2 7.7 28.5 0.89 9.9 0.1 6.3 5 1 2 7 7 7 0 Tetratricopeptide repeat TPR_4 PF07721.14 CRK37900.1 - 6.9 7.6 18.5 38 5.3 1.1 6.6 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 CRK37900.1 - 7.4 7.7 36.7 1.4 9.9 0.1 8.7 7 2 3 10 10 9 0 Tetratricopeptide repeat NCBP3 PF10309.9 CRK37902.1 - 1.7e-24 85.4 0.1 2.5e-24 84.9 0.1 1.3 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 RNA_bind PF08675.11 CRK37902.1 - 0.013 15.5 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 RNA binding domain RRM_3 PF08777.11 CRK37902.1 - 0.029 14.4 0.1 0.043 13.8 0.1 1.3 1 0 0 1 1 1 0 RNA binding motif RRM_1 PF00076.22 CRK37902.1 - 0.17 11.7 0.1 0.31 10.9 0.1 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Involucrin2 PF06994.11 CRK37903.1 - 0.022 14.8 0.0 0.048 13.8 0.0 1.6 1 0 0 1 1 1 0 Involucrin PEGSRP PF07623.11 CRK37903.1 - 1.8 8.4 6.4 3.6 7.5 1.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1584) Sec23_trunk PF04811.15 CRK37904.1 - 1.9e-79 266.7 0.0 3e-79 266.0 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 CRK37904.1 - 3.2e-30 104.7 0.1 7.6e-30 103.5 0.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 CRK37904.1 - 1.4e-25 89.1 0.3 1.1e-24 86.2 0.1 2.7 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Ribosomal_L11_N PF03946.14 CRK37904.1 - 1.8e-23 82.1 0.2 4e-23 81.0 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain TPR_1 PF00515.28 CRK37904.1 - 1.6e-17 62.5 1.9 0.001 18.8 0.0 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat zf-Sec23_Sec24 PF04810.15 CRK37904.1 - 2.6e-15 56.2 5.7 5.4e-15 55.2 5.7 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Ribosomal_L11 PF00298.19 CRK37904.1 - 6.9e-15 55.3 0.1 1.6e-14 54.2 0.1 1.7 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain TPR_2 PF07719.17 CRK37904.1 - 2e-13 49.3 2.9 0.06 13.5 0.0 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat Gelsolin PF00626.22 CRK37904.1 - 7.4e-12 45.0 0.0 1.8e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat TPR_8 PF13181.6 CRK37904.1 - 7.1e-11 41.4 2.0 0.0039 17.3 0.0 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 CRK37904.1 - 2.4e-10 39.9 2.8 0.04 13.6 0.0 5.4 4 1 2 6 6 6 3 TPR repeat TPR_10 PF13374.6 CRK37904.1 - 3.8e-10 39.3 5.9 0.042 13.7 0.1 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 CRK37904.1 - 5.1e-10 39.0 0.8 0.005 17.1 0.0 5.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 CRK37904.1 - 1.8e-07 31.3 2.8 0.0024 18.1 0.3 4.8 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 CRK37904.1 - 1.2e-06 28.9 1.7 0.34 11.8 0.0 4.5 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 CRK37904.1 - 6.4e-06 25.8 4.6 0.019 15.0 0.0 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 CRK37904.1 - 8.3e-06 26.4 0.1 0.51 11.0 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 CRK37904.1 - 0.0011 19.4 1.4 0.015 15.8 0.2 3.0 2 1 1 3 3 2 2 Tetratricopeptide repeat Vps36-NZF-N PF16988.5 CRK37904.1 - 0.039 13.4 0.4 0.13 11.7 0.1 2.0 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain TPR_6 PF13174.6 CRK37904.1 - 0.16 12.7 0.3 77 4.3 0.0 3.8 3 0 0 3 3 2 0 Tetratricopeptide repeat Glyco_transf_34 PF05637.12 CRK37905.1 - 1.9e-12 47.5 0.0 7.3e-07 29.2 0.0 2.4 1 1 1 2 2 2 2 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.14 CRK37905.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF273 PGAP1 PF07819.13 CRK37906.1 - 0.0068 16.1 0.0 0.0094 15.7 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein SCAB-Ig PF16709.5 CRK37906.1 - 0.0069 16.4 0.0 0.0093 16.0 0.0 1.2 1 0 0 1 1 1 1 Ig domain of plant-specific actin-binding protein Ribosomal_S3Ae PF01015.18 CRK37907.1 - 1.1e-117 390.8 6.3 8.9e-88 293.2 1.7 2.2 2 0 0 2 2 2 2 Ribosomal S3Ae family GTP_CH_N PF12471.8 CRK37907.1 - 5e-68 228.7 0.0 8.5e-68 227.9 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 CRK37907.1 - 4.2e-11 42.7 0.0 8.5e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 GTP cyclohydrolase II NEMO PF11577.8 CRK37907.1 - 0.15 12.1 8.8 2 8.5 0.1 3.2 4 0 0 4 4 4 0 NF-kappa-B essential modulator NEMO Elf1 PF05129.13 CRK37908.1 - 8.8e-28 96.2 0.2 1.1e-27 95.8 0.2 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Lar_restr_allev PF14354.6 CRK37908.1 - 0.065 13.6 0.4 0.11 13.0 0.4 1.3 1 0 0 1 1 1 0 Restriction alleviation protein Lar UPRTase PF14681.6 CRK37909.1 - 3.6e-79 265.0 0.0 5e-79 264.6 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 CRK37909.1 - 0.01 15.3 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase domain WAPL PF07814.13 CRK37910.1 - 1.6e-44 152.3 0.2 2.8e-44 151.4 0.2 1.4 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin Peptidase_C78 PF07910.13 CRK37911.1 - 2.1e-31 109.1 0.1 2.9e-31 108.6 0.1 1.1 1 0 0 1 1 1 1 Peptidase family C78 Ham1p_like PF01725.16 CRK37912.1 - 7.8e-56 189.0 0.0 3.3e-55 186.9 0.0 1.8 2 0 0 2 2 2 1 Ham1 family AAA_18 PF13238.6 CRK37912.1 - 1.4e-29 103.2 0.0 2.4e-29 102.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 CRK37912.1 - 4e-07 30.5 0.0 1.6e-06 28.6 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 CRK37912.1 - 9.3e-05 22.6 0.0 0.028 14.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain ADK PF00406.22 CRK37912.1 - 0.00027 21.1 0.0 0.0082 16.2 0.0 2.3 2 0 0 2 2 2 1 Adenylate kinase AAA_28 PF13521.6 CRK37912.1 - 0.00031 21.0 0.0 0.00093 19.5 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA PF00004.29 CRK37912.1 - 0.00046 20.6 0.0 0.0066 16.9 0.0 2.4 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Thymidylate_kin PF02223.17 CRK37912.1 - 0.00054 19.7 0.3 0.44 10.2 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase AAA_22 PF13401.6 CRK37912.1 - 0.002 18.4 0.0 0.008 16.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain Hydin_ADK PF17213.3 CRK37912.1 - 0.0028 17.9 0.0 0.0061 16.9 0.0 1.5 1 0 0 1 1 1 1 Hydin Adenylate kinase-like domain NTPase_1 PF03266.15 CRK37912.1 - 0.0036 17.2 0.1 0.012 15.6 0.1 1.9 1 0 0 1 1 1 1 NTPase AAA_16 PF13191.6 CRK37912.1 - 0.0041 17.5 0.2 0.0087 16.5 0.2 1.7 1 1 0 1 1 1 1 AAA ATPase domain dNK PF01712.19 CRK37912.1 - 0.011 15.5 0.0 4.8 7.0 0.0 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_19 PF13245.6 CRK37912.1 - 0.021 15.1 1.4 0.33 11.3 0.1 2.4 2 1 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 CRK37912.1 - 0.025 14.3 0.0 0.043 13.5 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase SKI PF01202.22 CRK37912.1 - 0.036 14.2 0.0 9.2 6.4 0.0 2.2 2 0 0 2 2 2 0 Shikimate kinase RNA_helicase PF00910.22 CRK37912.1 - 0.036 14.4 0.0 0.072 13.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase KTI12 PF08433.10 CRK37912.1 - 0.044 13.2 0.0 0.09 12.2 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_5 PF07728.14 CRK37912.1 - 0.076 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 CRK37912.1 - 0.088 12.5 0.0 0.22 11.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain 2-Hacid_dh_C PF02826.19 CRK37913.1 - 1.5e-51 174.3 0.0 2.4e-51 173.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CRK37913.1 - 1e-32 112.6 0.0 1.4e-32 112.2 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 CRK37913.1 - 0.00012 22.3 0.2 0.00028 21.1 0.2 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 CRK37913.1 - 0.0018 18.3 0.1 0.0039 17.3 0.1 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.12 CRK37913.1 - 0.0053 16.3 0.1 0.06 12.9 0.0 2.2 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain XdhC_C PF13478.6 CRK37913.1 - 0.015 15.8 0.1 0.11 13.0 0.0 2.2 2 0 0 2 2 2 0 XdhC Rossmann domain ACT PF01842.25 CRK37913.1 - 0.12 12.2 0.0 0.28 11.0 0.0 1.7 1 0 0 1 1 1 0 ACT domain Amdase PF17645.1 CRK37913.1 - 0.13 11.8 0.1 0.26 10.9 0.1 1.4 1 0 0 1 1 1 0 Arylmalonate decarboxylase 3HCDH_N PF02737.18 CRK37913.1 - 0.19 11.6 2.0 4.1 7.2 0.7 2.8 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CMAS PF02353.20 CRK37914.1 - 2.1e-33 115.8 0.0 2.8e-33 115.4 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 CRK37914.1 - 2.2e-17 63.5 0.0 4.1e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK37914.1 - 1.5e-16 60.9 0.0 2.8e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK37914.1 - 1.9e-15 56.9 0.0 3.4e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CRK37914.1 - 5.1e-12 45.9 0.0 8.7e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK37914.1 - 1.6e-11 44.8 0.0 3.1e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CRK37914.1 - 1.3e-08 34.6 0.0 2.9e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 CRK37914.1 - 1.3e-07 31.2 0.0 1.9e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DUF938 PF06080.12 CRK37914.1 - 2.6e-05 24.1 0.0 4.3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_4 PF02390.17 CRK37914.1 - 6.5e-05 22.5 0.0 0.00064 19.2 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase TehB PF03848.14 CRK37914.1 - 0.00027 20.4 0.0 0.0005 19.5 0.0 1.4 2 0 0 2 2 2 1 Tellurite resistance protein TehB PCMT PF01135.19 CRK37914.1 - 0.001 18.9 0.1 0.0047 16.7 0.0 2.2 1 1 1 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltr_RsmB-F PF01189.17 CRK37914.1 - 0.0012 18.6 0.0 0.0025 17.5 0.0 1.5 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_2 PF00891.18 CRK37914.1 - 0.0042 16.4 0.0 0.0071 15.7 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain GidB PF02527.15 CRK37914.1 - 0.018 14.4 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G UQ_con PF00179.26 CRK37916.1 - 7e-19 67.9 0.0 1.1e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CRK37916.1 - 0.03 14.6 0.0 0.053 13.8 0.0 1.3 1 0 0 1 1 1 0 RWD domain B-block_TFIIIC PF04182.12 CRK37917.1 - 1.3e-13 50.9 0.0 3.1e-13 49.7 0.0 1.7 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC Ebp2 PF05890.12 CRK37918.1 - 1.3e-91 306.9 10.7 1.3e-91 306.9 10.7 2.0 2 0 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 zf-MYND PF01753.18 CRK37919.1 - 3.9e-08 33.3 19.6 1.3e-07 31.5 19.6 2.0 1 0 0 1 1 1 1 MYND finger APC_u15 PF16636.5 CRK37919.1 - 0.42 11.1 4.4 1.2 9.6 4.4 1.8 1 0 0 1 1 1 0 Unstructured region on APC between APC_crr regions 5 and 6 BASP1 PF05466.12 CRK37919.1 - 9.6 6.1 14.5 1.5 8.8 6.2 2.2 2 0 0 2 2 2 0 Brain acid soluble protein 1 (BASP1 protein) Cation_efflux PF01545.21 CRK37921.1 - 4.4e-18 65.8 12.8 1.6e-14 54.1 8.0 2.2 2 0 0 2 2 2 2 Cation efflux family Dynamin_N PF00350.23 CRK37922.1 - 6.4e-65 218.3 0.0 3.5e-43 147.6 0.0 2.7 2 0 0 2 2 2 2 Dynamin family Dynamin_M PF01031.20 CRK37922.1 - 3.1e-11 43.0 0.0 1.7e-09 37.3 0.0 2.4 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.23 CRK37922.1 - 3.6e-10 39.9 0.0 0.00011 22.3 0.0 3.4 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 CRK37922.1 - 2.9e-06 27.8 2.8 0.098 13.0 0.0 3.5 4 0 0 4 4 4 2 AAA ATPase domain AAA_21 PF13304.6 CRK37922.1 - 6.5e-06 26.2 0.0 0.15 11.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_28 PF13521.6 CRK37922.1 - 8.1e-06 26.2 0.0 0.32 11.2 0.0 3.2 3 0 0 3 3 3 2 AAA domain Roc PF08477.13 CRK37922.1 - 5.6e-05 23.4 0.8 0.74 10.1 0.0 3.3 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase AAA_15 PF13175.6 CRK37922.1 - 0.00089 19.1 6.7 0.32 10.6 0.1 3.2 4 0 0 4 4 4 2 AAA ATPase domain FtsK_SpoIIIE PF01580.18 CRK37922.1 - 0.0014 18.0 0.3 2 7.7 0.0 2.7 3 0 0 3 3 3 2 FtsK/SpoIIIE family SSFA2_C PF14723.6 CRK37922.1 - 0.0036 17.2 0.4 6 6.7 0.0 3.1 3 0 0 3 3 3 2 Sperm-specific antigen 2 C-terminus Hepar_II_III PF07940.13 CRK37922.1 - 0.0074 15.9 0.1 4.4 6.8 0.0 2.3 2 0 0 2 2 2 2 Heparinase II/III-like protein AAA_29 PF13555.6 CRK37922.1 - 0.018 14.8 2.3 5.3 6.9 0.2 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.27 CRK37922.1 - 0.022 15.3 0.0 15 6.1 0.0 2.8 2 0 0 2 2 2 0 ABC transporter VirE PF05272.11 CRK37922.1 - 0.025 14.3 0.0 11 5.7 0.0 2.5 2 0 0 2 2 2 0 Virulence-associated protein E Ras PF00071.22 CRK37922.1 - 0.11 12.1 0.1 21 4.7 0.0 2.6 2 0 0 2 2 2 0 Ras family SMC_N PF02463.19 CRK37922.1 - 0.12 11.8 0.2 17 4.8 0.0 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain DLIC PF05783.11 CRK37922.1 - 0.28 9.9 1.3 16 4.2 0.1 2.3 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) IIGP PF05049.13 CRK37922.1 - 0.34 9.9 5.9 8.4 5.3 0.0 3.5 4 0 0 4 4 4 0 Interferon-inducible GTPase (IIGP) RHD3 PF05879.12 CRK37922.1 - 1 7.4 6.4 8.4 4.4 0.1 3.1 3 0 0 3 3 3 0 Root hair defective 3 GTP-binding protein (RHD3) GATase_4 PF13230.6 CRK37923.1 - 3.7e-17 62.1 0.1 5.5e-15 55.0 0.1 2.2 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 CRK37923.1 - 3.6e-09 36.9 0.0 7.2e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF202 PF02656.15 CRK37927.1 - 0.00074 19.9 2.6 0.0028 18.1 0.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Fusion_gly PF00523.18 CRK37929.1 - 0.19 10.0 0.1 0.21 9.8 0.1 1.0 1 0 0 1 1 1 0 Fusion glycoprotein F0 DUF1415 PF07209.12 CRK37931.1 - 0.048 13.4 0.0 0.051 13.3 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1415) NopRA1 PF16201.5 CRK37932.1 - 5.1e-21 75.2 0.2 5.5e-21 75.1 0.2 1.0 1 0 0 1 1 1 1 Nucleolar pre-ribosomal-associated protein 1 Peptidase_M14 PF00246.24 CRK37933.1 - 9.2e-05 22.4 0.0 0.0001 22.3 0.0 1.0 1 0 0 1 1 1 1 Zinc carboxypeptidase SR-25 PF10500.9 CRK37936.1 - 0.0011 18.6 11.6 0.0013 18.4 11.6 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein FAM176 PF14851.6 CRK37936.1 - 0.37 10.4 5.1 0.47 10.1 5.1 1.1 1 0 0 1 1 1 0 FAM176 family ABC_tran PF00005.27 CRK37937.1 - 1.3e-10 41.9 0.0 1.6e-10 41.6 0.0 1.1 1 0 0 1 1 1 1 ABC transporter Phage_tail_2 PF06199.11 CRK37937.1 - 0.0068 16.5 0.0 0.024 14.7 0.0 1.8 1 1 1 2 2 2 1 Phage tail tube protein PHO4 PF01384.20 CRK37939.1 - 1.5e-25 90.0 4.7 1.6e-25 89.9 4.7 1.0 1 0 0 1 1 1 1 Phosphate transporter family UPF0444 PF15475.6 CRK37939.1 - 0.068 13.4 0.9 0.078 13.3 0.6 1.4 1 1 0 1 1 1 0 Transmembrane protein C12orf23, UPF0444 TNFR_16_TM PF18422.1 CRK37940.1 - 0.19 11.7 0.4 0.19 11.7 0.4 1.6 2 0 0 2 2 2 0 Tumor necrosis factor receptor member 16 trans-membrane domain RPN2_C PF18004.1 CRK37946.1 - 0.0054 16.7 0.8 0.0061 16.5 0.8 1.0 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain Ferlin_C PF16165.5 CRK37946.1 - 0.04 13.9 0.6 0.041 13.8 0.6 1.1 1 0 0 1 1 1 0 Ferlin C-terminus Peptidase_S49_N PF08496.10 CRK37946.1 - 0.21 11.6 3.0 0.26 11.3 3.0 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal ISG65-75 PF11727.8 CRK37946.1 - 0.33 10.1 5.6 0.41 9.8 5.6 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein Glyco_transf_22 PF03901.17 CRK37955.1 - 6.4e-22 78.4 1.3 7.5e-22 78.1 1.3 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family MFS_1 PF07690.16 CRK37958.1 - 0.0065 15.4 6.0 0.0067 15.4 6.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1189 PF06691.11 CRK37958.1 - 0.014 15.0 0.6 0.016 14.8 0.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1189) S_4TM PF18159.1 CRK37958.1 - 0.093 12.0 0.2 0.1 11.9 0.2 1.1 1 0 0 1 1 1 0 SMODS-associating 4TM effector domain COX7C PF02935.16 CRK37958.1 - 0.1 12.9 2.1 0.98 9.7 0.1 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIc DUF4337 PF14235.6 CRK37958.1 - 0.21 11.7 1.1 0.25 11.4 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) BTP PF05232.12 CRK37958.1 - 0.39 10.8 4.5 1.4 9.0 2.6 2.1 1 1 1 2 2 2 0 Chlorhexidine efflux transporter PepSY_TM_like_2 PF16357.5 CRK37958.1 - 3.9 7.4 8.2 0.12 12.3 2.0 1.5 2 0 0 2 2 2 0 Putative PepSY_TM-like TIMELESS_C PF05029.13 CRK37960.1 - 3.1e-11 43.2 0.1 3.5e-11 43.0 0.1 1.0 1 0 0 1 1 1 1 Timeless protein C terminal region Prenyltrans PF00432.21 CRK37961.1 - 0.36 10.6 3.2 6.5 6.6 0.3 2.4 2 0 0 2 2 2 0 Prenyltransferase and squalene oxidase repeat Zn_clus PF00172.18 CRK37962.1 - 0.00061 19.9 6.9 0.0011 19.0 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pectate_lyase_3 PF12708.7 CRK37966.1 - 3.5e-25 89.1 0.7 3.6e-25 89.1 0.7 1.0 1 0 0 1 1 1 1 Pectate lyase superfamily protein Cas1_AcylT PF07779.12 CRK37967.1 - 1.3e-36 126.5 4.7 1.5e-36 126.4 4.7 1.0 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p AAA_2 PF07724.14 CRK37968.1 - 3.4e-10 40.3 0.0 3.7e-10 40.2 0.0 1.0 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 CRK37968.1 - 2.9e-05 24.5 0.0 3.3e-05 24.3 0.0 1.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CRK37968.1 - 0.00055 19.9 0.0 0.00063 19.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 CRK37968.1 - 0.083 12.9 0.1 0.094 12.8 0.1 1.1 1 0 0 1 1 1 0 AAA domain MCM PF00493.23 CRK37968.1 - 0.086 11.9 0.0 0.086 11.9 0.0 1.1 1 0 0 1 1 1 0 MCM P-loop domain DUF1918 PF08940.11 CRK37970.1 - 0.12 12.0 3.6 0.096 12.3 1.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1918) Mannitol_dh PF01232.23 CRK37973.1 - 2.2e-06 27.9 0.3 2.6e-06 27.7 0.3 1.1 1 0 0 1 1 1 1 Mannitol dehydrogenase Rossmann domain peroxidase PF00141.23 CRK37976.1 - 5.7e-06 26.2 0.0 7.5e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Peroxidase DUF5339 PF17274.2 CRK37978.1 - 0.086 13.7 1.2 1.3 9.9 0.1 2.4 1 1 1 2 2 2 0 Family of unknown function (DUF5339) CDH-cyt PF16010.5 CRK37980.1 - 1.9e-16 60.3 0.2 2.2e-16 60.0 0.2 1.0 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DOMON PF03351.17 CRK37980.1 - 4.5e-05 23.7 0.1 5.4e-05 23.4 0.1 1.1 1 0 0 1 1 1 1 DOMON domain FAA_hydrolase PF01557.18 CRK37981.1 - 1.6e-50 171.8 0.0 2e-50 171.5 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family 3-HAO PF06052.12 CRK37982.1 - 3.1e-64 215.2 0.0 3.6e-64 215.0 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 CRK37982.1 - 3.4e-06 26.7 0.0 5.8e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 CRK37982.1 - 4.8e-05 23.0 0.0 7.7e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Cupin ARD PF03079.14 CRK37982.1 - 0.004 17.4 0.0 0.0065 16.7 0.0 1.3 1 0 0 1 1 1 1 ARD/ARD' family DZR PF12773.7 CRK37982.1 - 0.017 15.2 2.1 0.033 14.2 2.1 1.5 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_5 PF13719.6 CRK37982.1 - 0.017 14.8 1.6 0.021 14.6 0.2 1.8 2 0 0 2 2 2 0 zinc-ribbon domain AraC_binding PF02311.19 CRK37982.1 - 0.029 14.3 0.0 0.049 13.5 0.0 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain Cupin_4 PF08007.12 CRK37982.1 - 0.039 13.4 0.0 0.044 13.2 0.0 1.2 1 0 0 1 1 1 0 Cupin superfamily protein C1_2 PF03107.16 CRK37982.1 - 0.72 10.2 3.8 16 5.9 0.3 2.3 1 1 1 2 2 2 0 C1 domain DUF1115 PF06544.12 CRK37983.1 - 1.7e-11 44.4 0.1 3.6e-11 43.4 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) Peptidase_M24_C PF16188.5 CRK37983.1 - 0.044 13.8 0.8 0.09 12.8 0.1 1.9 2 0 0 2 2 2 0 C-terminal region of peptidase_M24 Sorting_nexin PF03700.13 CRK37983.1 - 0.054 14.1 0.3 0.099 13.2 0.3 1.3 1 0 0 1 1 1 0 Sorting nexin, N-terminal domain Glyco_hydro_71 PF03659.14 CRK37986.1 - 6.1e-117 390.6 6.3 2.1e-77 260.5 1.9 2.4 1 1 1 2 2 2 2 Glycosyl hydrolase family 71 Ank_2 PF12796.7 CRK37987.1 - 3.5e-26 91.6 0.0 1.9e-07 31.5 0.1 4.5 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CRK37987.1 - 3.6e-20 72.1 2.7 3.5e-05 24.2 0.1 7.1 4 3 4 8 8 8 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 CRK37987.1 - 6.9e-19 66.0 0.5 0.023 15.2 0.0 8.7 9 0 0 9 9 9 5 Ankyrin repeat Ank_5 PF13857.6 CRK37987.1 - 4.9e-17 61.8 1.4 0.0024 18.2 0.2 6.4 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 CRK37987.1 - 1.7e-11 44.0 5.0 0.13 12.7 0.1 7.2 6 2 0 6 6 6 4 Ankyrin repeat Helo_like_N PF17111.5 CRK37987.1 - 0.094 12.1 0.1 0.17 11.2 0.1 1.4 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins NUDIX PF00293.28 CRK37988.1 - 5.4e-08 32.9 0.0 1.3e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 NUDIX domain MCM PF00493.23 CRK37989.1 - 1.6e-99 331.5 0.0 2.7e-99 330.8 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CRK37989.1 - 2e-39 134.3 1.2 2.7e-39 133.9 0.2 1.7 2 0 0 2 2 2 1 MCM OB domain MCM_lid PF17855.1 CRK37989.1 - 5.4e-29 100.5 2.5 1.1e-28 99.4 2.5 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CRK37989.1 - 9.1e-18 64.8 0.0 2.8e-17 63.2 0.0 1.9 1 0 0 1 1 1 1 MCM N-terminal domain AAA_5 PF07728.14 CRK37989.1 - 0.00011 22.2 0.0 0.00032 20.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 CRK37989.1 - 0.00017 21.0 0.0 0.0014 18.1 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CRK37989.1 - 0.0042 16.9 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_2 PF17863.1 CRK37989.1 - 0.015 15.1 0.2 0.037 13.9 0.2 1.6 1 0 0 1 1 1 0 AAA lid domain HLH PF00010.26 CRK37989.1 - 0.14 12.2 0.1 0.44 10.6 0.1 1.8 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain Clat_adaptor_s PF01217.20 CRK37990.1 - 1.2e-14 54.4 0.1 1e-12 48.2 0.2 2.1 2 0 0 2 2 2 2 Clathrin adaptor complex small chain Sua5_yciO_yrdC PF01300.18 CRK37991.1 - 1.6e-52 177.6 0.0 3.3e-51 173.3 0.0 2.1 1 1 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 CRK37991.1 - 1.1e-27 97.2 0.0 2.1e-27 96.3 0.0 1.5 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding COG4 PF08318.12 CRK37992.1 - 8.1e-160 531.4 0.0 2.1e-101 339.4 0.0 2.4 1 1 1 2 2 2 2 COG4 transport protein Cation_ATPase_C PF00689.21 CRK37992.1 - 1.2e-39 135.9 0.9 1.8e-39 135.3 0.9 1.3 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus MCM_OB PF17207.3 CRK37992.1 - 1.9e-39 134.4 0.2 3.4e-39 133.5 0.2 1.4 1 0 0 1 1 1 1 MCM OB domain MCM PF00493.23 CRK37992.1 - 8.5e-27 93.7 0.0 2.4e-26 92.3 0.0 1.7 2 0 0 2 2 2 1 MCM P-loop domain MCM_N PF14551.6 CRK37992.1 - 1.3e-17 64.3 0.0 3.7e-17 62.8 0.0 1.9 1 0 0 1 1 1 1 MCM N-terminal domain TetR_C_12 PF16914.5 CRK37992.1 - 0.044 13.9 0.6 0.38 10.9 0.2 2.7 1 1 1 2 2 2 0 Bacterial transcriptional repressor C-terminal Clat_adaptor_s PF01217.20 CRK37993.1 - 2.5e-14 53.4 0.1 2.9e-12 46.7 0.2 2.0 2 0 0 2 2 2 2 Clathrin adaptor complex small chain DUF4804 PF16062.5 CRK37993.1 - 0.019 13.8 0.0 0.026 13.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4804) Sua5_yciO_yrdC PF01300.18 CRK37994.1 - 2.1e-52 177.2 0.0 3e-52 176.7 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 CRK37994.1 - 6.6e-27 94.7 0.0 1.3e-26 93.7 0.0 1.5 1 1 0 1 1 1 1 Putative GTP-binding controlling metal-binding adh_short PF00106.25 CRK37995.1 - 1.1e-24 87.0 0.0 2.7e-22 79.2 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK37995.1 - 3.1e-15 56.4 0.0 1.3e-13 51.1 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK37995.1 - 6e-09 36.1 0.0 1.5e-08 34.7 0.0 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 CRK37995.1 - 2.3e-06 27.3 0.0 3.3e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 CRK37995.1 - 0.0032 17.7 0.0 0.0059 16.9 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 CRK37995.1 - 0.0035 16.5 0.0 0.0063 15.7 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Amidohydro_2 PF04909.14 CRK37995.1 - 0.03 14.1 0.0 0.059 13.1 0.0 1.5 1 0 0 1 1 1 0 Amidohydrolase GDP_Man_Dehyd PF16363.5 CRK37995.1 - 0.085 12.2 0.0 9.9 5.4 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Shikimate_DH PF01488.20 CRK37995.1 - 0.12 12.4 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase COG4 PF08318.12 CRK37996.1 - 1.5e-78 264.2 0.0 1e-45 156.3 0.0 2.2 2 0 0 2 2 2 2 COG4 transport protein Cation_ATPase_N PF00690.26 CRK37996.1 - 7.5e-12 44.8 0.0 1.7e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus TetR_C_12 PF16914.5 CRK37996.1 - 0.011 15.8 1.7 0.11 12.6 0.2 2.8 2 1 1 3 3 3 0 Bacterial transcriptional repressor C-terminal VTC PF09359.10 CRK37997.1 - 4.7e-185 613.3 0.1 9e-96 320.5 0.0 2.3 1 1 1 2 2 2 2 VTC domain E1-E2_ATPase PF00122.20 CRK37997.1 - 3.9e-71 238.3 0.0 1.3e-43 148.6 0.0 3.7 2 1 1 3 3 3 3 E1-E2 ATPase Hexokinase_2 PF03727.16 CRK37997.1 - 6e-45 153.5 0.0 1e-44 152.7 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Cys_Met_Meta_PP PF01053.20 CRK37997.1 - 1.4e-39 135.8 0.0 2e-19 69.4 0.0 2.2 2 0 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Hexokinase_1 PF00349.21 CRK37997.1 - 8.2e-29 100.9 0.0 1.5e-28 100.0 0.0 1.4 1 0 0 1 1 1 1 Hexokinase Cation_ATPase_N PF00690.26 CRK37997.1 - 1.4e-25 88.7 0.0 8.4e-17 60.6 0.0 2.6 2 0 0 2 2 2 2 Cation transporter/ATPase, N-terminus DUF202 PF02656.15 CRK37997.1 - 1.3e-24 86.4 13.5 1e-11 45.1 2.9 3.4 2 0 0 2 2 2 2 Domain of unknown function (DUF202) Hydrolase PF00702.26 CRK37997.1 - 9.6e-21 75.0 0.7 5.1e-20 72.7 0.7 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase SPX PF03105.19 CRK37997.1 - 1.5e-10 41.6 8.8 5.4e-05 23.3 0.1 3.5 1 1 1 3 3 3 2 SPX domain Cation_ATPase PF13246.6 CRK37997.1 - 1.8e-10 40.7 0.0 4.6e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Phage_holin_3_6 PF07332.11 CRK37997.1 - 0.0021 18.1 0.4 4.3 7.4 0.1 2.9 2 0 0 2 2 2 2 Putative Actinobacterial Holin-X, holin superfamily III Hydrolase_3 PF08282.12 CRK37997.1 - 0.006 16.4 0.3 0.006 16.4 0.3 2.2 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Transposase_20 PF02371.16 CRK37997.1 - 0.061 13.6 0.0 17 5.8 0.0 2.6 2 0 0 2 2 2 0 Transposase IS116/IS110/IS902 family DUF2805 PF10985.8 CRK37997.1 - 0.18 12.2 1.8 23 5.5 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2805) PMP22_Claudin PF00822.20 CRK37997.1 - 0.46 10.3 10.8 2.9 7.7 1.9 2.4 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family LapA_dom PF06305.11 CRK37997.1 - 9.9 6.1 12.1 83 3.1 0.3 4.7 4 0 0 4 4 4 0 Lipopolysaccharide assembly protein A domain Cation_ATPase_C PF00689.21 CRK37998.1 - 4.4e-41 140.6 0.9 5e-41 140.4 0.9 1.0 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 CRK37999.1 - 1.1e-10 41.4 2.1 2e-10 40.5 2.1 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 CRK38000.1 - 6.4e-10 39.7 0.1 1.2e-09 38.8 0.0 1.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CRK38000.1 - 3.8e-05 23.5 0.4 4.7e-05 23.3 0.4 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Ank_2 PF12796.7 CRK38001.1 - 0.011 16.3 0.0 0.056 14.0 0.0 2.0 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CRK38001.1 - 0.12 13.0 0.1 7.2 7.3 0.0 2.8 2 1 0 2 2 2 0 Ankyrin repeats (many copies) Hexokinase_2 PF03727.16 CRK38002.1 - 3.9e-83 278.6 0.0 5.1e-83 278.2 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 CRK38002.1 - 1.2e-71 240.7 0.0 2.5e-71 239.7 0.0 1.5 2 0 0 2 2 2 1 Hexokinase TPP_enzyme_N PF02776.18 CRK38002.1 - 0.16 11.5 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Ribophorin_I PF04597.14 CRK38003.1 - 1.7e-151 505.4 0.0 2e-151 505.2 0.0 1.0 1 0 0 1 1 1 1 Ribophorin I CREPT PF16566.5 CRK38003.1 - 0.02 15.1 0.0 0.042 14.0 0.0 1.5 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Pil1 PF13805.6 CRK38004.1 - 1.7e-109 365.4 3.8 2.1e-109 365.1 3.8 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 HSP20 PF00011.21 CRK38006.1 - 1.7e-07 31.3 0.0 0.0019 18.3 0.1 2.8 1 1 2 3 3 3 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CRK38006.1 - 0.0017 17.8 0.0 0.019 14.5 0.0 2.3 2 1 0 2 2 2 1 HSP20-like domain found in ArsA Glyco_hydro_71 PF03659.14 CRK38008.1 - 1.4e-130 435.5 1.3 1.7e-130 435.2 1.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 PhoD PF09423.10 CRK38009.1 - 4e-06 26.1 0.4 0.00095 18.3 0.1 2.1 2 0 0 2 2 2 2 PhoD-like phosphatase DUF3336 PF11815.8 CRK38010.1 - 8.4e-34 116.2 0.2 8.4e-33 113.0 0.0 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF3336) Patatin PF01734.22 CRK38010.1 - 2.1e-12 47.7 3.9 3.1e-12 47.1 0.8 2.2 2 0 0 2 2 2 1 Patatin-like phospholipase Sm_multidrug_ex PF06695.11 CRK38010.1 - 0.1 13.2 0.7 0.35 11.5 0.3 2.0 2 0 0 2 2 2 0 Putative small multi-drug export protein Leo1 PF04004.13 CRK38011.1 - 4.7e-31 107.9 0.0 9.3e-31 106.9 0.0 1.5 1 0 0 1 1 1 1 Leo1-like protein CWC25 PF12542.8 CRK38011.1 - 0.031 15.2 0.3 0.031 15.2 0.3 2.6 4 0 0 4 4 4 0 Pre-mRNA splicing factor Arteri_nsp7a PF16749.5 CRK38011.1 - 0.1 12.7 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Arterivirus nonstructural protein 7 alpha Mob1_phocein PF03637.17 CRK38012.1 - 3.4e-44 150.9 0.0 6.6e-44 149.9 0.0 1.5 1 1 0 1 1 1 1 Mob1/phocein family bZIP_1 PF00170.21 CRK38013.1 - 2.7e-15 56.2 43.2 1.4e-07 31.5 13.3 4.8 2 2 2 4 4 4 2 bZIP transcription factor bZIP_Maf PF03131.17 CRK38013.1 - 8.7e-11 42.2 32.6 6e-05 23.5 12.3 3.0 2 0 0 2 2 2 2 bZIP Maf transcription factor bZIP_2 PF07716.15 CRK38013.1 - 0.00016 21.7 47.1 0.088 12.9 16.8 5.0 4 2 0 4 4 4 2 Basic region leucine zipper FapA PF03961.13 CRK38013.1 - 0.00061 18.5 22.4 0.052 12.2 7.2 2.2 2 0 0 2 2 2 2 Flagellar Assembly Protein A GSAP-16 PF14959.6 CRK38013.1 - 0.01 15.7 0.0 9.3 6.2 0.0 2.8 2 0 0 2 2 2 0 gamma-Secretase-activating protein C-term Surfac_D-trimer PF09006.11 CRK38013.1 - 0.029 14.2 0.0 15 5.6 0.0 2.7 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation KASH_CCD PF14662.6 CRK38013.1 - 0.16 11.8 43.9 1.7 8.4 18.0 2.6 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH IL11 PF07400.11 CRK38013.1 - 0.84 9.3 13.8 4.2 7.0 3.1 2.7 2 0 0 2 2 2 0 Interleukin 11 HMMR_N PF15905.5 CRK38013.1 - 1.2 8.5 35.3 3.8 6.9 13.6 2.4 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal PI_PP_I PF18363.1 CRK38013.1 - 2.8 8.2 7.7 22 5.3 0.9 2.9 2 0 0 2 2 2 0 Phosphoinositide phosphatase insertion domain DUF5320 PF17253.2 CRK38013.1 - 3.4 8.8 13.1 7.2 7.8 0.4 4.0 2 2 2 4 4 4 0 Family of unknown function (DUF5320) AAA_23 PF13476.6 CRK38013.1 - 3.6 8.0 27.1 10 6.6 9.6 2.6 2 0 0 2 2 2 0 AAA domain Sel1 PF08238.12 CRK38014.1 - 2.4e-17 63.0 11.4 0.037 14.7 0.0 6.5 6 0 0 6 6 6 6 Sel1 repeat zf-CCCH PF00642.24 CRK38014.1 - 1.5e-08 34.3 53.9 0.00011 22.0 0.4 9.7 8 2 2 10 10 10 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CRK38014.1 - 7.8e-07 28.8 31.6 0.017 14.9 0.2 6.7 6 0 0 6 6 6 3 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CRK38014.1 - 2.6e-06 27.3 64.7 0.00016 21.6 0.7 10.4 10 2 0 10 10 10 4 Zinc finger domain Torus PF16131.5 CRK38014.1 - 0.013 16.2 49.6 0.63 10.8 0.2 8.7 2 2 6 8 8 8 0 Torus domain E_raikovi_mat PF06360.11 CRK38014.1 - 2.2 8.8 6.9 23 5.5 0.8 2.8 2 0 0 2 2 2 0 Euplotes raikovi mating pheromone THOC7 PF05615.13 CRK38015.1 - 1.9e-40 138.2 4.8 1.9e-40 138.2 4.8 3.2 2 1 1 3 3 3 1 Tho complex subunit 7 FAM76 PF16046.5 CRK38015.1 - 0.0021 17.5 5.7 0.35 10.2 0.2 2.2 2 0 0 2 2 2 2 FAM76 protein GTSE1_N PF15259.6 CRK38015.1 - 0.0026 17.9 2.3 1.7 8.8 0.2 2.4 2 0 0 2 2 2 2 G-2 and S-phase expressed 1 DUF4600 PF15372.6 CRK38015.1 - 0.16 12.4 11.1 4.1 7.9 5.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) INT_SG_DDX_CT_C PF15300.6 CRK38015.1 - 0.24 11.2 2.0 19 5.2 0.2 2.5 2 0 0 2 2 2 0 INTS6/SAGE1/DDX26B/CT45 C-terminus CAML PF14963.6 CRK38015.1 - 0.58 10.2 15.6 0.74 9.9 3.4 2.6 2 1 0 2 2 2 0 Calcium signal-modulating cyclophilin ligand CCDC144C PF14915.6 CRK38015.1 - 1.3 8.0 17.7 1.1 8.4 7.7 2.2 2 0 0 2 2 2 0 CCDC144C protein coiled-coil region RTBV_P46 PF06216.11 CRK38015.1 - 1.4 7.7 6.0 9.2 5.0 0.4 2.9 2 1 1 3 3 3 0 Rice tungro bacilliform virus P46 protein OmpH PF03938.14 CRK38015.1 - 1.6 9.1 10.7 5.4 7.4 4.9 2.7 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) Rootletin PF15035.6 CRK38015.1 - 1.9 8.5 21.5 0.81 9.7 3.1 2.6 2 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion APG6_N PF17675.1 CRK38015.1 - 5.1 7.6 19.4 1.7 9.2 0.7 3.4 2 1 0 2 2 2 0 Apg6 coiled-coil region TBCA PF02970.16 CRK38016.1 - 7.9e-22 77.4 1.9 1e-21 77.0 1.9 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A Mei4 PF13971.6 CRK38016.1 - 0.04 13.4 0.1 0.049 13.1 0.1 1.1 1 0 0 1 1 1 0 Meiosis-specific protein Mei4 SlyX PF04102.12 CRK38016.1 - 1.4 9.6 5.7 4.6 7.9 0.2 2.4 1 1 1 2 2 2 0 SlyX TBCA PF02970.16 CRK38017.1 - 7.9e-22 77.4 1.9 1e-21 77.0 1.9 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A Mei4 PF13971.6 CRK38017.1 - 0.04 13.4 0.1 0.049 13.1 0.1 1.1 1 0 0 1 1 1 0 Meiosis-specific protein Mei4 SlyX PF04102.12 CRK38017.1 - 1.4 9.6 5.7 4.6 7.9 0.2 2.4 1 1 1 2 2 2 0 SlyX Miga PF10265.9 CRK38018.1 - 1 8.2 4.6 1.3 7.9 4.6 1.1 1 0 0 1 1 1 0 Mitoguardin Rad21_Rec8_N PF04825.13 CRK38019.1 - 5.2e-37 126.4 0.0 9.9e-37 125.5 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 CRK38019.1 - 1.4e-07 30.7 0.0 2.6e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein EURL PF06937.11 CRK38019.1 - 0.11 11.9 0.1 0.18 11.2 0.1 1.2 1 0 0 1 1 1 0 EURL protein THOC7 PF05615.13 CRK38021.1 - 2.1e-30 105.7 0.5 3.7e-30 104.9 0.5 1.3 1 0 0 1 1 1 1 Tho complex subunit 7 Glyco_transf_15 PF01793.16 CRK38023.1 - 5.1e-84 282.3 0.1 9.3e-84 281.4 0.1 1.3 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase EXS PF03124.14 CRK38025.1 - 5.5e-21 75.2 5.8 6.6e-21 75.0 5.8 1.1 1 0 0 1 1 1 1 EXS family Glyco_transf_15 PF01793.16 CRK38026.1 - 1.7e-82 277.3 1.2 7.3e-82 275.2 1.2 1.7 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase EXS PF03124.14 CRK38029.1 - 1.5e-41 142.9 7.6 1.8e-41 142.6 7.6 1.0 1 0 0 1 1 1 1 EXS family Pex2_Pex12 PF04757.14 CRK38031.1 - 3e-37 128.4 6.3 3.6e-37 128.1 6.3 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_UBOX PF13445.6 CRK38031.1 - 5.4e-09 35.9 1.9 9.6e-09 35.1 1.9 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 CRK38031.1 - 2.3e-07 31.0 1.7 3.7e-07 30.4 1.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CRK38031.1 - 3.5e-07 30.0 1.1 5.7e-07 29.3 1.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CRK38031.1 - 3.7e-07 29.9 0.4 6.1e-07 29.2 0.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CRK38031.1 - 1.5e-06 28.2 1.5 2.6e-06 27.5 1.5 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 CRK38031.1 - 3.7e-05 23.5 0.9 6.1e-05 22.8 0.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CRK38031.1 - 4e-05 23.5 0.8 6.9e-05 22.7 0.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 CRK38031.1 - 0.0017 18.6 0.7 0.0033 17.7 0.7 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 CRK38031.1 - 0.0028 17.5 0.6 0.0052 16.6 0.6 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 CRK38031.1 - 0.0053 16.6 1.5 0.0087 15.9 1.5 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-Nse PF11789.8 CRK38031.1 - 0.069 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Transposase_23 PF03017.14 CRK38031.1 - 0.083 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 TNP1/EN/SPM transposase zf-RING_10 PF16685.5 CRK38031.1 - 0.16 12.1 0.9 0.33 11.1 0.9 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 Pex2_Pex12 PF04757.14 CRK38033.1 - 1.8e-37 129.2 6.3 2.1e-37 128.9 6.3 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.6 CRK38033.1 - 1.1e-10 41.7 8.2 1.6e-10 41.1 8.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CRK38033.1 - 8.5e-10 38.3 7.6 1.3e-09 37.7 7.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CRK38033.1 - 1.1e-09 37.9 5.4 1.8e-09 37.3 5.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CRK38033.1 - 2.8e-09 36.7 4.9 4.2e-09 36.1 4.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CRK38033.1 - 8.5e-08 32.1 6.8 1.6e-07 31.2 6.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CRK38033.1 - 3.4e-07 30.1 4.4 5.4e-07 29.5 4.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 CRK38033.1 - 4.4e-07 30.1 5.6 8.3e-07 29.2 5.6 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 CRK38033.1 - 1.8e-06 27.7 6.4 2.8e-06 27.1 6.4 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 CRK38033.1 - 5.8e-06 26.4 7.0 9.5e-06 25.7 7.0 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 CRK38033.1 - 6e-05 22.8 2.8 0.00011 22.0 2.8 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 CRK38033.1 - 0.0018 18.4 4.7 0.0035 17.5 4.7 1.4 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-Nse PF11789.8 CRK38033.1 - 0.0033 17.2 0.8 0.0054 16.5 0.8 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Transposase_23 PF03017.14 CRK38033.1 - 0.069 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 TNP1/EN/SPM transposase zf-ANAPC11 PF12861.7 CRK38033.1 - 0.09 12.8 1.4 0.15 12.1 1.4 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 CRK38033.1 - 0.15 11.9 6.0 0.35 10.7 6.0 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-LYAR PF08790.11 CRK38034.1 - 9.2e-08 31.8 0.3 4.2e-07 29.8 0.1 2.0 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger DUF2235 PF09994.9 CRK38036.1 - 9.7e-66 222.0 0.0 5.4e-65 219.6 0.0 2.0 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) zf-LYAR PF08790.11 CRK38036.1 - 4.2 7.4 4.6 2 8.4 1.5 2.2 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger FAD_binding_3 PF01494.19 CRK38038.1 - 1.8e-06 27.5 0.0 1.8e-06 27.5 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 CRK38038.1 - 0.0053 17.0 0.0 0.022 15.0 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 CRK38038.1 - 0.014 16.0 0.1 0.019 15.5 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CRK38038.1 - 0.033 13.4 0.0 0.035 13.3 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CRK38038.1 - 0.072 12.7 0.0 0.072 12.7 0.0 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 CRK38038.1 - 0.14 11.1 0.0 0.18 10.8 0.0 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 CRK38038.1 - 0.19 10.9 0.1 0.22 10.7 0.1 1.1 1 0 0 1 1 1 0 Thi4 family CBM_1 PF00734.18 CRK38040.1 - 5.3e-11 42.3 15.9 1.1e-10 41.3 12.9 2.5 2 0 0 2 2 2 1 Fungal cellulose binding domain Pec_lyase_C PF00544.19 CRK38040.1 - 1.7e-10 40.8 3.3 2.4e-09 37.1 3.3 2.1 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 CRK38040.1 - 0.00018 21.4 6.6 0.00029 20.7 6.6 1.2 1 0 0 1 1 1 1 Right handed beta helix region Hydrolase_4 PF12146.8 CRK38041.1 - 3.4e-20 72.3 0.0 7.8e-15 54.8 0.1 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CRK38041.1 - 1.1e-14 54.7 0.2 4.2e-09 36.4 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 CRK38041.1 - 2e-06 27.4 0.0 4.8e-06 26.2 0.0 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.12 CRK38041.1 - 6.8e-06 25.0 0.0 0.011 14.5 0.0 3.0 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 CRK38041.1 - 9.6e-06 26.4 0.1 3.7e-05 24.4 0.1 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family FSH1 PF03959.13 CRK38041.1 - 3.2e-05 23.7 0.0 9e-05 22.2 0.0 1.7 2 1 0 2 2 2 1 Serine hydrolase (FSH1) DLH PF01738.18 CRK38041.1 - 4.7e-05 23.0 0.0 0.031 13.8 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Peptidase_S15 PF02129.18 CRK38041.1 - 6.5e-05 22.6 0.0 0.23 11.0 0.0 2.2 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) DUF818 PF05677.12 CRK38041.1 - 0.00042 19.4 0.1 0.00059 18.9 0.1 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) BAAT_C PF08840.11 CRK38041.1 - 0.0031 17.5 0.0 0.056 13.4 0.0 2.2 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.13 CRK38041.1 - 0.0051 16.7 0.0 0.012 15.4 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 CRK38041.1 - 0.0084 15.9 0.0 0.2 11.4 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.13 CRK38041.1 - 0.011 15.5 0.2 0.18 11.5 0.0 2.2 2 0 0 2 2 2 0 PGAP1-like protein Abhydrolase_2 PF02230.16 CRK38041.1 - 0.021 14.6 0.0 1.5 8.6 0.0 2.2 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Esterase PF00756.20 CRK38041.1 - 0.041 13.5 0.1 0.067 12.8 0.1 1.2 1 0 0 1 1 1 0 Putative esterase Lipase_3 PF01764.25 CRK38041.1 - 0.057 13.3 0.0 0.086 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) LIDHydrolase PF10230.9 CRK38041.1 - 0.089 12.3 0.0 0.73 9.3 0.0 2.0 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase DUF2974 PF11187.8 CRK38041.1 - 0.17 11.4 0.2 0.27 10.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) R3H PF01424.22 CRK38042.1 - 1.4e-16 60.2 0.1 2.4e-16 59.5 0.1 1.4 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.17 CRK38042.1 - 2e-06 27.7 55.4 0.0002 21.4 13.6 12.6 12 2 0 12 12 12 7 NF-X1 type zinc finger WSC PF01822.19 CRK38043.1 - 1e-88 291.6 77.1 4.3e-19 68.5 12.4 5.3 5 0 0 5 5 5 5 WSC domain Glyoxal_oxid_N PF07250.11 CRK38043.1 - 5e-27 94.6 0.0 1.1e-26 93.5 0.0 1.5 1 0 0 1 1 1 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 CRK38043.1 - 3.9e-20 71.9 0.0 8.3e-20 70.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_2 PF07646.15 CRK38043.1 - 0.07 13.1 0.1 0.89 9.6 0.0 2.9 3 0 0 3 3 3 0 Kelch motif Sulfotransfer_4 PF17784.1 CRK38044.1 - 1e-70 237.9 0.3 1.3e-70 237.6 0.3 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 CRK38044.1 - 0.00062 20.2 1.0 0.046 14.1 0.3 2.4 1 1 1 2 2 2 2 Sulfotransferase family MFS_1 PF07690.16 CRK38045.1 - 1.3e-17 63.7 29.4 1.3e-17 63.7 29.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Pam17 PF08566.10 CRK38045.1 - 5.9 6.7 6.9 15 5.4 0.5 2.3 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 Arylsulfotran_2 PF14269.6 CRK38046.1 - 1.2e-57 195.6 0.4 1.8e-57 195.0 0.4 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 CRK38046.1 - 6.6e-21 74.6 0.0 2.3e-20 72.9 0.0 1.6 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) PQQ PF01011.21 CRK38046.1 - 0.059 13.3 0.0 3.2 7.8 0.0 3.4 3 0 0 3 3 3 0 PQQ enzyme repeat PQQ_2 PF13360.6 CRK38046.1 - 0.06 12.9 0.4 0.23 11.0 0.2 2.2 2 1 0 2 2 2 0 PQQ-like domain SfLAP PF11139.8 CRK38046.1 - 1.2 8.5 3.0 0.48 9.8 0.3 1.6 2 0 0 2 2 2 0 Sap, sulfolipid-1-addressing protein PP-binding PF00550.25 CRK38049.1 - 4.7e-07 30.1 0.0 7.2e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site NuA4 PF09340.10 CRK38051.1 - 1.3e-23 82.6 0.2 1.5e-23 82.4 0.2 1.0 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 DUF1319 PF07028.11 CRK38051.1 - 0.068 13.4 0.1 0.092 13.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) IGPD PF00475.18 CRK38056.1 - 4.2e-24 85.5 0.0 4.8e-24 85.3 0.0 1.1 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase CMAS PF02353.20 CRK38057.1 - 0.0004 19.8 0.0 0.0004 19.8 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 CRK38057.1 - 0.042 13.7 0.0 0.044 13.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 CRK38057.1 - 0.057 13.2 0.0 0.057 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CsoSCA PF08936.10 CRK38057.1 - 0.069 11.8 0.0 0.071 11.7 0.0 1.0 1 0 0 1 1 1 0 Carboxysome Shell Carbonic Anhydrase MetW PF07021.12 CRK38057.1 - 0.15 11.6 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_31 PF13847.6 CRK38057.1 - 0.2 11.4 0.1 0.28 11.0 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain FMO-like PF00743.19 CRK38058.1 - 0.00027 19.5 0.0 0.0003 19.3 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 CRK38058.1 - 0.00063 19.0 0.0 0.00067 18.9 0.0 1.0 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 CRK38058.1 - 0.08 12.2 0.0 0.082 12.1 0.0 1.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UPF0542 PF15086.6 CRK38059.1 - 0.022 14.7 0.0 0.029 14.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 CoA_trans PF01144.23 CRK38060.1 - 1.9e-18 66.7 0.0 2.1e-18 66.5 0.0 1.0 1 0 0 1 1 1 1 Coenzyme A transferase DHR-2 PF06920.13 CRK38060.1 - 0.092 11.4 0.0 0.1 11.2 0.0 1.0 1 0 0 1 1 1 0 Dock homology region 2 BAH PF01426.18 CRK38063.1 - 1e-10 41.5 0.0 1e-10 41.5 0.0 1.1 1 0 0 1 1 1 1 BAH domain FmdA_AmdA PF03069.15 CRK38063.1 - 5e-10 38.8 0.1 6.8e-10 38.3 0.1 1.2 1 0 0 1 1 1 1 Acetamidase/Formamidase family ABC_membrane PF00664.23 CRK38064.1 - 1.7e-13 50.8 2.1 1.9e-13 50.7 2.1 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region kleA_kleC PF17383.2 CRK38067.1 - 0.14 12.5 0.0 0.19 12.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized KorC regulated protein A tRNA-synt_2 PF00152.20 CRK38070.1 - 1e-11 44.5 0.0 1.2e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF676 PF05057.14 CRK38072.1 - 5.6e-19 68.5 0.2 5.9e-19 68.4 0.2 1.0 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.25 CRK38072.1 - 0.0021 17.9 0.0 0.0024 17.7 0.0 1.0 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 CRK38072.1 - 0.0076 16.0 0.0 0.0082 15.9 0.0 1.1 1 0 0 1 1 1 1 PGAP1-like protein DUF915 PF06028.11 CRK38072.1 - 0.043 13.1 0.0 0.048 13.0 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Palm_thioest PF02089.15 CRK38072.1 - 0.056 13.3 0.0 0.064 13.1 0.0 1.0 1 0 0 1 1 1 0 Palmitoyl protein thioesterase LCAT PF02450.15 CRK38072.1 - 0.059 12.5 0.0 0.066 12.4 0.0 1.0 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.8 CRK38072.1 - 0.073 12.3 0.0 0.073 12.3 0.0 1.1 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Proton_antipo_N PF00662.20 CRK38072.1 - 0.14 12.2 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus p450 PF00067.22 CRK38073.1 - 1.1e-10 40.9 0.0 1.3e-10 40.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MCM2_N PF12619.8 CRK38077.1 - 5.5e-23 81.9 8.8 6.1e-23 81.8 8.8 1.0 1 0 0 1 1 1 1 Mini-chromosome maintenance protein 2 Peroxin-3 PF04882.12 CRK38078.1 - 1.4e-16 60.5 0.0 1.6e-16 60.4 0.0 1.0 1 0 0 1 1 1 1 Peroxin-3 Nup96 PF12110.8 CRK38079.1 - 0.017 14.2 0.0 0.017 14.2 0.0 1.1 1 0 0 1 1 1 0 Nuclear protein 96 Methyltransf_11 PF08241.12 CRK38079.1 - 0.13 12.9 0.0 0.18 12.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF383 PF04063.14 CRK38081.1 - 2.8e-33 115.2 0.0 3.1e-33 115.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF383) DUF3419 PF11899.8 CRK38084.1 - 3.1e-47 161.6 0.0 3.5e-47 161.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) DLEU7 PF15760.5 CRK38095.1 - 4.9 6.6 6.5 5.5 6.4 6.5 1.2 1 1 0 1 1 1 0 Leukemia-associated protein 7 Aldo_ket_red PF00248.21 CRK38104.1 - 7.1e-16 58.3 0.0 7.8e-16 58.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HlyIII PF03006.20 CRK38126.1 - 4.2e-44 150.9 8.9 4.7e-44 150.8 8.9 1.0 1 0 0 1 1 1 1 Haemolysin-III related Chal_sti_synt_C PF02797.15 CRK38143.1 - 4.6e-10 39.7 0.0 5.6e-10 39.4 0.0 1.0 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain ACP_syn_III_C PF08541.10 CRK38143.1 - 0.0032 17.6 0.0 0.0054 16.9 0.0 1.3 1 1 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal AA_permease PF00324.21 CRK38165.1 - 3.1e-104 349.3 42.2 6.3e-56 189.9 15.0 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease_2 PF13520.6 CRK38165.1 - 3.4e-24 85.4 46.9 2.8e-14 52.8 19.1 2.0 1 1 1 2 2 2 2 Amino acid permease DUF2101 PF09874.9 CRK38165.1 - 5.5 6.6 12.2 0.9 9.2 4.2 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2101) D-ser_dehydrat PF14031.6 CRK38167.1 - 8.6e-23 80.8 2.6 1.8e-22 79.8 2.6 1.6 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 CRK38167.1 - 1.6e-13 50.8 1.8 1.9e-13 50.6 0.1 1.9 2 0 0 2 2 2 1 Alanine racemase, N-terminal domain PhoLip_ATPase_C PF16212.5 CRK38169.1 - 1.4e-81 274.0 18.0 1.4e-81 274.0 18.0 1.9 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CRK38169.1 - 4.1e-26 90.5 4.7 1.2e-25 89.0 4.7 1.9 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 CRK38169.1 - 4.8e-11 42.6 0.0 3.9e-10 39.7 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CRK38169.1 - 9.4e-11 42.4 3.6 4.8e-06 27.0 1.0 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 CRK38169.1 - 2e-08 34.0 1.8 2.7e-08 33.5 0.1 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CRK38169.1 - 0.0018 18.1 0.4 0.0092 15.7 0.1 2.0 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Mt_ATP-synt_B PF05405.14 CRK38169.1 - 0.038 13.6 0.1 0.099 12.3 0.1 1.7 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Catalase PF00199.19 CRK38173.1 - 1.6e-159 531.1 0.2 2e-159 530.8 0.2 1.1 1 0 0 1 1 1 1 Catalase Catalase_C PF18011.1 CRK38173.1 - 1.3e-45 154.8 0.0 2e-45 154.1 0.0 1.3 1 0 0 1 1 1 1 C-terminal domain found in long catalases Nucleoside_tran PF01733.18 CRK38173.1 - 2.1e-34 119.3 0.2 7.5e-34 117.5 0.2 1.9 1 1 0 1 1 1 1 Nucleoside transporter Catalase-rel PF06628.12 CRK38173.1 - 5.3e-18 65.0 0.1 9.5e-18 64.2 0.1 1.4 1 0 0 1 1 1 1 Catalase-related immune-responsive Ins_P5_2-kin PF06090.12 CRK38176.1 - 1.4e-34 120.0 0.0 4.1e-34 118.5 0.0 1.6 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase PhaP_Bmeg PF09602.10 CRK38180.1 - 0.072 13.0 1.3 0.1 12.5 1.3 1.2 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Ribosomal_60s PF00428.19 CRK38180.1 - 7.6 7.2 21.0 2 9.0 8.7 2.9 3 0 0 3 3 3 0 60s Acidic ribosomal protein SYF2 PF08231.12 CRK38182.1 - 2.5e-54 184.0 12.5 2.5e-54 184.0 12.5 1.7 3 0 0 3 3 3 1 SYF2 splicing factor Mito_fiss_reg PF05308.11 CRK38182.1 - 0.091 12.8 11.7 0.19 11.8 11.7 1.6 1 0 0 1 1 1 0 Mitochondrial fission regulator YEATS PF03366.16 CRK38184.1 - 1.2e-09 37.9 0.2 1.5e-09 37.7 0.2 1.1 1 0 0 1 1 1 1 YEATS family Epimerase PF01370.21 CRK38185.1 - 1.1e-05 25.1 0.0 1.6e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 CRK38185.1 - 0.0014 18.5 0.0 0.0021 18.0 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 CRK38185.1 - 0.017 14.2 0.0 0.023 13.7 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 CRK38185.1 - 0.039 13.4 0.0 0.058 12.8 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 CRK38185.1 - 0.066 12.3 0.0 0.093 11.8 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain TFIIA PF03153.13 CRK38185.1 - 0.25 11.3 13.1 0.27 11.2 13.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ecl1 PF12855.7 CRK38188.1 - 7.3e-37 128.2 19.3 7.3e-37 128.2 19.3 1.9 2 0 0 2 2 2 1 ECL1/2/3 zinc binding proteins zf-FLZ PF04570.14 CRK38188.1 - 0.033 13.7 2.9 0.065 12.7 2.9 1.4 1 0 0 1 1 1 0 zinc-finger of the FCS-type, C2-C2 PLATZ PF04640.14 CRK38188.1 - 0.058 14.0 0.7 0.093 13.4 0.7 1.3 1 0 0 1 1 1 0 PLATZ transcription factor HNH_repeat PF18780.1 CRK38188.1 - 0.27 11.1 0.2 0.48 10.3 0.2 1.4 1 0 0 1 1 1 0 Homing endonuclease repeat DUF2256 PF10013.9 CRK38188.1 - 2.6 8.2 4.4 36 4.6 4.4 2.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) Haspin_kinase PF12330.8 CRK38191.1 - 1.8e-30 106.1 0.0 2.4e-30 105.7 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain DUF1682 PF07946.14 CRK38193.1 - 4.3e-106 354.8 0.4 5e-106 354.6 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Big_3 PF07523.12 CRK38193.1 - 0.12 12.6 0.0 20 5.6 0.0 2.6 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) MRP-S26 PF14943.6 CRK38193.1 - 0.28 11.1 11.1 0.47 10.4 11.1 1.4 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 DUF4407 PF14362.6 CRK38193.1 - 4.5 6.5 8.1 7.4 5.8 8.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Thiamine_BP PF01910.17 CRK38194.1 - 1.8e-31 107.9 0.1 2.1e-31 107.7 0.1 1.0 1 0 0 1 1 1 1 Thiamine-binding protein Baculo_F PF12259.8 CRK38194.1 - 0.021 13.4 0.0 0.025 13.1 0.0 1.1 1 0 0 1 1 1 0 Baculovirus F protein SAD_SRA PF02182.17 CRK38195.1 - 5.4e-06 26.2 0.2 9.6e-06 25.4 0.0 1.5 2 0 0 2 2 2 1 SAD/SRA domain TPR_2 PF07719.17 CRK38197.1 - 1.9 8.8 8.9 0.39 11.0 0.2 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat U3_snoRNA_assoc PF08297.11 CRK38198.1 - 4.2e-12 46.6 0.4 4.2e-12 46.6 0.4 3.7 3 2 0 3 3 3 1 U3 snoRNA associated DALR_2 PF09190.11 CRK38198.1 - 0.03 14.8 2.6 0.092 13.2 2.6 1.8 1 0 0 1 1 1 0 DALR domain PH_10 PF15411.6 CRK38199.1 - 3e-29 101.8 1.0 5.8e-29 100.8 1.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain VWA PF00092.28 CRK38199.1 - 2.2e-15 57.3 0.0 3.7e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 CRK38199.1 - 4e-11 43.1 0.0 1.2e-10 41.6 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 CRK38199.1 - 3.2e-07 31.0 0.0 7.1e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-RING_2 PF13639.6 CRK38199.1 - 0.00026 21.3 6.1 0.00045 20.5 6.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 CRK38199.1 - 0.00039 20.3 6.4 0.00066 19.6 6.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 CRK38199.1 - 0.009 15.6 3.1 0.009 15.6 3.1 1.6 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 CRK38199.1 - 0.013 15.7 3.2 0.027 14.7 3.2 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING-like PF08746.11 CRK38199.1 - 0.019 15.3 4.5 0.033 14.5 4.5 1.4 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_3 PF13920.6 CRK38199.1 - 0.046 13.6 2.8 0.083 12.8 2.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CRK38199.1 - 0.051 13.4 5.2 0.094 12.6 5.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CRK38199.1 - 0.1 12.5 6.0 0.19 11.6 6.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CRK38199.1 - 0.19 11.5 4.7 0.39 10.5 4.7 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-UDP PF14569.6 CRK38199.1 - 0.2 11.8 0.7 0.38 10.9 0.7 1.4 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C3H2C3 PF17122.5 CRK38199.1 - 0.52 10.4 5.4 1.1 9.3 5.4 1.6 1 0 0 1 1 1 0 Zinc-finger zf-RING_UBOX PF13445.6 CRK38199.1 - 4.8 7.3 5.8 13 5.9 5.8 1.8 1 0 0 1 1 1 0 RING-type zinc-finger Cpn60_TCP1 PF00118.24 CRK38201.1 - 1.2e-126 423.3 1.3 2.9e-102 342.8 0.1 2.0 1 1 1 2 2 2 2 TCP-1/cpn60 chaperonin family PrpR_N PF06506.11 CRK38201.1 - 0.033 13.7 0.3 0.11 12.1 0.1 1.9 2 0 0 2 2 2 0 Propionate catabolism activator EAL PF00563.20 CRK38201.1 - 0.054 13.0 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 EAL domain HMG_box PF00505.19 CRK38202.1 - 1.9e-09 37.8 1.0 5.7e-09 36.3 1.0 1.9 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CRK38202.1 - 0.00026 21.5 4.4 0.00029 21.4 2.3 2.2 2 0 0 2 2 2 1 HMG-box domain ChaB PF06150.12 CRK38202.1 - 0.25 12.0 9.8 0.56 10.8 6.3 3.2 2 1 1 3 3 3 0 ChaB DUF155 PF02582.14 CRK38203.1 - 6.3e-103 342.3 6.6 5.2e-52 176.5 0.8 2.2 2 0 0 2 2 2 2 Uncharacterised ACR, YagE family COG1723 UPF0449 PF15136.6 CRK38203.1 - 0.0053 17.2 0.0 2.1 8.9 0.0 2.6 2 0 0 2 2 2 2 Uncharacterised protein family UPF0449 LNP1 PF15419.6 CRK38203.1 - 0.02 15.1 0.0 6 7.1 0.0 2.5 2 0 0 2 2 2 0 Leukemia NUP98 fusion partner 1 HTH_29 PF13551.6 CRK38203.1 - 0.086 12.9 0.1 9.6 6.3 0.0 2.6 2 0 0 2 2 2 0 Winged helix-turn helix Sacchrp_dh_NADP PF03435.18 CRK38204.1 - 1.1e-16 61.3 0.0 2.4e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 CRK38204.1 - 0.00078 19.9 0.0 0.0013 19.1 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Ribosomal_L37ae PF01780.19 CRK38205.1 - 7.5e-41 138.1 8.5 8.4e-41 138.0 8.5 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family DUF1451 PF07295.11 CRK38205.1 - 0.05 13.6 1.2 0.07 13.2 1.2 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain Zn_Tnp_IS1595 PF12760.7 CRK38205.1 - 0.052 13.5 4.4 0.083 12.9 4.4 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain C1_2 PF03107.16 CRK38205.1 - 0.059 13.7 2.3 1.8 8.9 2.5 2.1 1 1 1 2 2 2 0 C1 domain zf-H2C2_2 PF13465.6 CRK38205.1 - 1.9 9.1 6.3 9.7 6.8 1.2 2.3 1 1 1 2 2 2 0 Zinc-finger double domain Rotamase_3 PF13616.6 CRK38206.1 - 1.1e-15 58.2 0.1 2.3e-15 57.1 0.1 1.6 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 CRK38206.1 - 1.5e-13 51.5 0.0 2.4e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 CRK38206.1 - 0.00014 22.7 0.5 0.00054 20.8 0.0 1.8 1 1 0 2 2 2 1 PPIC-type PPIASE domain Ribosomal_L7Ae PF01248.26 CRK38207.1 - 2.5e-27 94.4 0.9 3.2e-27 94.1 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 CRK38207.1 - 0.082 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 PELOTA RNA binding domain Glyco_transf_90 PF05686.12 CRK38208.1 - 1e-10 41.1 12.1 3e-07 29.7 7.9 4.0 3 1 0 3 3 3 3 Glycosyl transferase family 90 Paf1 PF03985.13 CRK38209.1 - 4e-80 269.9 0.1 4.5e-80 269.7 0.1 1.0 1 0 0 1 1 1 1 Paf1 NAD_binding_1 PF00175.21 CRK38210.1 - 2.5e-11 44.2 0.4 1.4e-10 41.8 0.0 2.5 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Kelch_5 PF13854.6 CRK38210.1 - 1.3e-09 37.8 0.2 1.7e-08 34.3 0.1 2.9 2 0 0 2 2 2 1 Kelch motif Globin PF00042.22 CRK38210.1 - 2.7e-07 31.1 0.0 1.3e-06 29.0 0.0 2.3 2 0 0 2 2 1 1 Globin FAD_binding_6 PF00970.24 CRK38210.1 - 1.2e-05 25.6 0.0 7.5e-05 23.0 0.0 2.4 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain CLASP_N PF12348.8 CRK38210.1 - 2.5e-05 23.9 0.0 0.0035 16.9 0.0 2.5 2 0 0 2 2 2 1 CLASP N terminal Protoglobin PF11563.8 CRK38210.1 - 0.00014 21.8 0.0 0.00048 20.1 0.0 1.9 1 0 0 1 1 1 1 Protoglobin NAD_binding_6 PF08030.12 CRK38210.1 - 0.02 15.0 0.0 0.065 13.3 0.0 1.8 1 0 0 1 1 1 0 Ferric reductase NAD binding domain Cnd1 PF12717.7 CRK38210.1 - 0.036 14.1 0.1 2.5 8.1 0.0 2.6 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CRK38210.1 - 0.046 14.0 1.2 6.2 7.4 0.1 4.3 5 0 0 5 5 3 0 HEAT repeat Kelch_3 PF13415.6 CRK38210.1 - 0.063 13.6 2.8 0.47 10.8 0.0 3.9 3 0 0 3 3 3 0 Galactose oxidase, central domain HALZ PF02183.18 CRK38210.1 - 0.07 13.4 7.6 0.14 12.4 1.2 2.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper PRKG1_interact PF15898.5 CRK38210.1 - 0.27 12.1 10.7 0.84 10.6 10.7 1.9 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain Baculo_PEP_C PF04513.12 CRK38210.1 - 1.1 9.3 3.2 2.1 8.4 1.5 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Jnk-SapK_ap_N PF09744.9 CRK38210.1 - 1.1 9.4 10.9 2.6 8.3 10.9 1.5 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Spc7 PF08317.11 CRK38210.1 - 1.3 7.8 4.9 3 6.7 4.9 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein APG6_N PF17675.1 CRK38210.1 - 2.4 8.7 7.6 8 7.0 7.6 1.9 1 0 0 1 1 1 0 Apg6 coiled-coil region CorA PF01544.18 CRK38210.1 - 2.8 7.2 6.2 6 6.1 6.2 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Fez1 PF06818.15 CRK38210.1 - 2.9 8.3 6.9 6.4 7.2 6.9 1.5 1 0 0 1 1 1 0 Fez1 ADIP PF11559.8 CRK38210.1 - 3.7 7.6 10.2 8.1 6.5 10.2 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF3584 PF12128.8 CRK38210.1 - 7.4 3.9 8.4 11 3.3 8.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) GAS PF13851.6 CRK38210.1 - 8.4 5.7 10.0 20 4.4 10.0 1.6 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding WD40 PF00400.32 CRK38211.1 - 2e-53 177.1 18.7 7.9e-09 36.0 0.8 8.6 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK38211.1 - 1.5e-10 41.2 0.0 0.0044 17.3 0.0 4.8 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CRK38211.1 - 7.9e-07 28.1 0.0 0.0018 17.0 0.1 3.5 4 1 1 5 5 5 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 CRK38211.1 - 0.00039 19.3 0.0 0.088 11.5 0.0 2.8 3 0 0 3 3 3 2 Nup133 N terminal like SAPS PF04499.15 CRK38212.1 - 8.6e-100 334.8 1.4 8.6e-100 334.8 1.4 2.6 2 1 0 2 2 2 1 SIT4 phosphatase-associated protein zf-LITAF-like PF10601.9 CRK38212.1 - 4.3e-18 65.3 6.0 6.5e-18 64.8 6.0 1.3 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain GCFC PF07842.12 CRK38213.1 - 1.1e-42 146.5 0.7 2.6e-42 145.3 0.2 1.6 1 1 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein SAPS PF04499.15 CRK38214.1 - 3.8e-55 187.6 0.0 3.8e-55 187.6 0.0 2.1 2 1 1 3 3 3 1 SIT4 phosphatase-associated protein TIP_N PF12457.8 CRK38215.1 - 5.3e-15 55.7 12.1 5.3e-15 55.7 12.1 1.9 1 1 1 2 2 2 1 Tuftelin interacting protein N terminal Abhydrolase_3 PF07859.13 CRK38216.1 - 6.9e-30 104.5 0.0 1.1e-29 103.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 CRK38216.1 - 0.0017 17.3 0.0 0.003 16.5 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family DUF1100 PF06500.11 CRK38216.1 - 0.24 10.1 0.0 0.98 8.1 0.0 1.9 3 0 0 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF1100) Condensation PF00668.20 CRK38217.1 - 5.8e-74 249.4 0.0 1.1e-28 100.1 0.0 4.3 4 1 0 4 4 4 4 Condensation domain AMP-binding PF00501.28 CRK38217.1 - 1.6e-33 116.0 0.0 2.5e-33 115.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 CRK38217.1 - 3.4e-07 30.5 0.8 0.0068 16.7 0.0 3.2 2 0 0 2 2 2 2 Phosphopantetheine attachment site bZIP_1 PF00170.21 CRK38218.1 - 2e-10 40.6 5.1 3.6e-10 39.8 5.1 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CRK38218.1 - 8.7e-05 22.5 7.4 0.00013 21.9 7.4 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 CRK38218.1 - 0.00019 21.9 3.6 0.00033 21.1 3.6 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor AA_permease PF00324.21 CRK38219.1 - 2.2e-145 484.9 39.7 2.7e-145 484.6 39.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CRK38219.1 - 1.2e-39 136.4 40.1 1.2e-39 136.4 40.1 1.3 1 1 0 1 1 1 1 Amino acid permease Sod_Fe_C PF02777.18 CRK38220.1 - 2.2e-37 127.3 0.1 3.5e-37 126.7 0.1 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 CRK38220.1 - 1.6e-30 105.4 1.2 2.9e-30 104.6 1.2 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain HHH_2 PF12826.7 CRK38220.1 - 0.098 12.8 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif Sld5 PF05916.11 CRK38221.1 - 6.6e-18 65.2 0.0 9.1e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein MFS_1 PF07690.16 CRK38222.1 - 9.2e-20 70.9 26.5 9.2e-20 70.9 26.5 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily VIT1 PF01988.19 CRK38222.1 - 2 8.2 4.8 1.6 8.5 0.4 2.7 2 1 0 2 2 2 0 VIT family Fungal_trans PF04082.18 CRK38223.1 - 2.2e-11 43.3 0.0 5.1e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aldo_ket_red PF00248.21 CRK38224.1 - 4.6e-60 203.3 0.0 6.2e-60 202.9 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_88 PF07470.13 CRK38224.1 - 2.4e-05 23.6 0.6 4.5e-05 22.7 0.6 1.4 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 MatE PF01554.18 CRK38225.1 - 5e-05 23.0 17.8 0.016 14.9 0.9 3.6 3 1 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 CRK38225.1 - 0.00065 19.8 1.7 0.00065 19.8 1.7 4.1 4 1 0 5 5 5 1 Polysaccharide biosynthesis C-terminal domain FixQ PF05545.11 CRK38225.1 - 0.074 13.0 0.6 0.34 10.9 0.0 2.5 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ DUF2277 PF10041.9 CRK38225.1 - 0.12 12.7 0.0 0.75 10.2 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2277) DUF3429 PF11911.8 CRK38228.1 - 1.9e-45 154.7 9.0 2.6e-45 154.3 9.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) SHR-BD PF06650.12 CRK38229.1 - 1.2e-96 323.3 0.0 6.4e-95 317.6 0.0 2.6 2 0 0 2 2 2 1 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_mid_rpt PF16910.5 CRK38229.1 - 7.5e-90 300.5 21.1 2e-89 299.1 1.1 5.8 6 1 1 7 7 7 2 Repeating coiled region of VPS13 VPS13 PF16908.5 CRK38229.1 - 5.7e-85 284.9 3.9 1.6e-83 280.1 0.0 3.8 4 0 0 4 4 4 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 CRK38229.1 - 1.1e-74 250.0 6.2 1e-69 233.9 0.4 2.8 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 CRK38229.1 - 5.1e-40 136.2 0.1 1.8e-39 134.5 0.1 2.1 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 CRK38229.1 - 3.1e-08 33.8 0.0 2.7e-07 30.8 0.0 2.6 3 0 0 3 3 3 1 Autophagy-related protein C terminal domain TORC_M PF12885.7 CRK38229.1 - 0.066 13.1 0.0 0.066 13.1 0.0 2.4 3 0 0 3 3 3 0 Transducer of regulated CREB activity middle domain Nucleos_tra2_C PF07662.13 CRK38232.1 - 3e-67 226.5 3.7 3e-67 226.5 3.7 2.8 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 CRK38232.1 - 5.9e-22 78.1 2.1 5.9e-22 78.1 2.1 2.8 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus PBP_N PF17093.5 CRK38232.1 - 0.59 10.4 4.8 1 9.6 0.0 2.7 2 0 0 2 2 2 0 Penicillin-binding protein N-terminus Gate PF07670.14 CRK38232.1 - 1.1 9.6 16.7 0.032 14.5 7.4 3.0 2 1 0 2 2 2 0 Nucleoside recognition CBM_1 PF00734.18 CRK38235.1 - 2e-13 50.0 11.2 6.3e-13 48.4 11.2 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain Peptidase_M64 PF09471.10 CRK38235.1 - 0.035 13.7 0.7 0.088 12.3 0.2 1.8 1 1 0 2 2 2 0 IgA Peptidase M64 Sugar_tr PF00083.24 CRK38244.1 - 4.2e-12 45.7 0.0 4.4e-12 45.6 0.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter DrsE PF02635.15 CRK38244.1 - 0.016 15.6 0.0 0.018 15.4 0.0 1.1 1 0 0 1 1 1 0 DsrE/DsrF-like family YbjQ_1 PF01906.17 CRK38246.1 - 6.7e-14 52.4 0.0 7e-14 52.3 0.0 1.0 1 0 0 1 1 1 1 Putative heavy-metal-binding Synapsin_N PF10581.9 CRK38247.1 - 0.15 12.0 2.2 0.31 11.0 2.2 1.7 1 1 0 1 1 1 0 Synapsin N-terminal NAD_binding_8 PF13450.6 CRK38248.1 - 0.075 13.3 0.2 0.62 10.3 0.0 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain bacHORMA_2 PF18173.1 CRK38249.1 - 0.066 13.1 0.0 0.07 13.0 0.0 1.1 1 0 0 1 1 1 0 Bacterial HORMA domain 2 Peptidase_M19 PF01244.21 CRK38249.1 - 0.082 12.1 0.0 0.088 12.0 0.0 1.1 1 0 0 1 1 1 0 Membrane dipeptidase (Peptidase family M19) tRNA_synthFbeta PF17759.1 CRK38252.1 - 1.4e-18 67.1 0.0 1.6e-18 67.0 0.0 1.0 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain SCO1-SenC PF02630.14 CRK38256.1 - 5.2e-14 52.3 0.0 6.2e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AAA_16 PF13191.6 CRK38257.1 - 0.0012 19.3 0.0 0.0018 18.7 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 CRK38257.1 - 0.0016 17.7 0.0 0.0018 17.5 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 CRK38257.1 - 0.0019 18.4 0.0 0.0042 17.4 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CRK38257.1 - 0.016 14.9 0.1 0.028 14.2 0.1 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CRK38257.1 - 0.021 15.4 0.1 0.039 14.5 0.1 1.5 1 1 0 1 1 1 0 ABC transporter ATPase_2 PF01637.18 CRK38257.1 - 0.026 14.4 0.0 0.052 13.4 0.0 1.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA PF00004.29 CRK38257.1 - 0.027 14.9 1.2 0.054 13.9 1.2 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 CRK38257.1 - 0.037 14.6 1.1 0.077 13.6 1.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CRK38257.1 - 0.038 13.7 0.5 0.06 13.1 0.1 1.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 CRK38257.1 - 0.038 13.9 0.1 0.062 13.2 0.1 1.4 1 0 0 1 1 1 0 NACHT domain AFG1_ATPase PF03969.16 CRK38257.1 - 0.043 12.7 0.0 0.045 12.6 0.0 1.0 1 0 0 1 1 1 0 AFG1-like ATPase RsgA_GTPase PF03193.16 CRK38257.1 - 0.06 13.3 0.0 0.072 13.0 0.0 1.3 1 1 0 1 1 1 0 RsgA GTPase Rad17 PF03215.15 CRK38257.1 - 0.082 12.8 0.0 0.084 12.8 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_33 PF13671.6 CRK38257.1 - 0.084 13.0 0.4 0.084 13.0 0.4 1.8 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 CRK38257.1 - 0.085 12.9 0.3 0.17 12.0 0.1 1.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase NTPase_1 PF03266.15 CRK38257.1 - 0.11 12.4 0.9 0.18 11.7 0.9 1.3 1 0 0 1 1 1 0 NTPase AAA_14 PF13173.6 CRK38257.1 - 0.12 12.4 0.1 0.18 11.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 CRK38257.1 - 0.13 12.6 0.1 0.21 11.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 CRK38257.1 - 0.14 11.9 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CRK38257.1 - 0.17 11.9 0.3 0.3 11.1 0.3 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 CRK38257.1 - 0.19 12.0 0.4 0.36 11.1 0.4 1.4 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 CRK38257.1 - 0.19 11.3 0.2 0.28 10.7 0.2 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 CRK38257.1 - 0.2 11.4 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ALIX_LYPXL_bnd PF13949.6 CRK38259.1 - 1.2e-13 51.1 0.0 1.2e-13 51.0 0.0 1.0 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV TCL1_MTCP1 PF01840.17 CRK38260.1 - 0.056 13.1 0.0 0.069 12.8 0.0 1.1 1 0 0 1 1 1 0 TCL1/MTCP1 family Peptidase_M16_C PF05193.21 CRK38261.1 - 4.5e-07 30.1 0.0 2.1e-06 27.9 0.0 1.9 2 0 0 2 2 2 1 Peptidase M16 inactive domain Orn_DAP_Arg_deC PF00278.22 CRK38261.1 - 0.14 12.4 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Taxilin PF09728.9 CRK38262.1 - 1.4e-60 205.1 37.8 1.6e-60 204.9 37.8 1.1 1 0 0 1 1 1 1 Myosin-like coiled-coil protein NMO PF03060.15 CRK38262.1 - 9.8e-42 143.5 0.4 9.8e-42 143.5 0.4 1.9 1 1 0 1 1 1 1 Nitronate monooxygenase DUF4810 PF16068.5 CRK38262.1 - 0.00024 21.6 0.1 0.00024 21.6 0.1 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF4810) IMPDH PF00478.25 CRK38262.1 - 0.0055 15.7 1.0 0.095 11.7 1.0 2.2 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain GHMP_kinases_C PF08544.13 CRK38262.1 - 0.029 14.7 0.1 0.15 12.5 0.0 2.2 2 0 0 2 2 2 0 GHMP kinases C terminal DUF1635 PF07795.11 CRK38262.1 - 0.23 11.3 7.3 0.072 13.0 4.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) DHR10 PF18595.1 CRK38262.1 - 0.25 11.4 23.5 0.37 10.9 22.2 2.1 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain Laminin_I PF06008.14 CRK38262.1 - 0.41 10.3 20.9 0.7 9.5 11.7 2.2 1 1 1 2 2 2 0 Laminin Domain I FMN_dh PF01070.18 CRK38262.1 - 0.91 8.5 10.2 0.05 12.6 4.2 1.9 2 0 0 2 2 2 0 FMN-dependent dehydrogenase RmuC PF02646.16 CRK38262.1 - 0.97 8.5 17.7 0.17 11.0 5.9 2.3 1 1 1 2 2 2 0 RmuC family DUF4239 PF14023.6 CRK38262.1 - 1.2 8.8 7.9 2.2 8.0 7.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) Sec20 PF03908.13 CRK38262.1 - 4 7.4 8.1 2 8.4 1.8 2.7 1 1 2 3 3 3 0 Sec20 FliD_N PF02465.18 CRK38262.1 - 4.5 8.0 12.1 3.5 8.4 3.3 2.5 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus V_ATPase_I PF01496.19 CRK38262.1 - 5.8 4.7 12.6 8.1 4.2 12.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FAM76 PF16046.5 CRK38262.1 - 9.5 5.5 16.6 15 4.8 16.6 1.2 1 0 0 1 1 1 0 FAM76 protein CTI PF06934.11 CRK38264.1 - 0.0057 15.2 0.0 0.0072 14.9 0.0 1.1 1 0 0 1 1 1 1 Fatty acid cis/trans isomerase (CTI) DUF2115 PF09888.9 CRK38264.1 - 0.029 14.9 0.1 0.048 14.2 0.1 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) DUF4705 PF15788.5 CRK38267.1 - 0.057 13.7 2.3 0.063 13.5 2.3 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4705) JAB PF01398.21 CRK38269.1 - 7.1e-21 74.4 0.0 7.7e-21 74.3 0.0 1.0 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 CRK38269.1 - 0.0055 16.5 0.0 0.0057 16.4 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Aegerolysin PF06355.13 CRK38269.1 - 0.044 13.9 0.0 0.048 13.7 0.0 1.0 1 0 0 1 1 1 0 Aegerolysin AA_permease_2 PF13520.6 CRK38270.1 - 2.2e-13 49.8 0.2 2.3e-13 49.8 0.2 1.0 1 0 0 1 1 1 1 Amino acid permease Anticodon_1 PF08264.13 CRK38272.1 - 1.4e-14 54.3 0.0 1.5e-14 54.2 0.0 1.0 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA RPN7 PF10602.9 CRK38272.1 - 0.053 13.2 0.0 0.055 13.2 0.0 1.1 1 0 0 1 1 1 0 26S proteasome subunit RPN7 Pam17 PF08566.10 CRK38273.1 - 2.4e-13 50.2 0.5 2.5e-13 50.2 0.5 1.0 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 Glyco_hydro_28 PF00295.17 CRK38274.1 - 2.5e-15 56.4 1.0 2.7e-15 56.3 1.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 CRK38274.1 - 0.0023 17.8 0.2 0.0027 17.6 0.2 1.1 1 0 0 1 1 1 1 Right handed beta helix region RSN1_7TM PF02714.15 CRK38276.1 - 1.7e-11 44.0 0.0 1.7e-11 44.0 0.0 1.0 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate Glycos_transf_1 PF00534.20 CRK38278.1 - 5.1e-09 35.9 0.0 5.4e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CRK38278.1 - 4.1e-07 30.5 0.0 4.2e-07 30.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferases group 1 Fcf2 PF08698.11 CRK38285.1 - 3.1e-05 24.3 1.2 3.1e-05 24.3 1.2 1.6 2 0 0 2 2 2 1 Fcf2 pre-rRNA processing EthD PF07110.11 CRK38290.1 - 1.6e-10 42.0 0.0 1.8e-10 41.8 0.0 1.1 1 0 0 1 1 1 1 EthD domain adh_short PF00106.25 CRK38291.1 - 1.8e-34 118.9 0.0 2.3e-34 118.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK38291.1 - 2.8e-28 99.0 0.0 3.8e-28 98.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK38291.1 - 0.006 16.5 0.2 0.068 13.1 0.1 2.6 3 1 0 3 3 3 1 KR domain adh_short PF00106.25 CRK38292.1 - 1.2e-37 129.3 0.0 1.8e-37 128.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK38292.1 - 5.7e-27 94.8 0.0 7.2e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 CRK38292.1 - 0.00017 21.0 0.0 0.00025 20.5 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.10 CRK38292.1 - 0.00073 19.5 0.0 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 CRK38292.1 - 0.01 15.7 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 NAD(P)H-binding Oxidored_FMN PF00724.20 CRK38293.1 - 6.8e-88 295.2 0.0 7.9e-88 295.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.24 CRK38293.1 - 0.01 15.3 0.0 5.3 6.4 0.0 2.5 2 1 1 3 3 3 0 Xylose isomerase-like TIM barrel DUF1848 PF08902.11 CRK38293.1 - 0.18 11.5 0.0 0.27 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) Sugar_tr PF00083.24 CRK38294.1 - 3.9e-13 49.1 5.6 4.7e-13 48.8 5.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK38294.1 - 4e-05 22.7 7.4 4.9e-05 22.4 7.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Propep_M14 PF02244.16 CRK38295.1 - 0.016 15.6 0.0 0.019 15.4 0.0 1.2 1 0 0 1 1 1 0 Carboxypeptidase activation peptide Pectinesterase PF01095.19 CRK38296.1 - 9.8e-16 57.3 0.2 1e-15 57.2 0.2 1.0 1 0 0 1 1 1 1 Pectinesterase GMC_oxred_N PF00732.19 CRK38299.1 - 8.7e-49 166.5 0.0 1.1e-48 166.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CRK38299.1 - 6.8e-28 98.0 0.0 1.4e-27 97.0 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 CRK38299.1 - 5.4e-05 22.9 7.9 0.00043 20.0 7.9 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 CRK38299.1 - 0.00021 20.7 1.8 0.027 13.7 0.6 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CRK38299.1 - 0.00083 18.7 0.1 0.003 16.8 0.2 1.8 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 CRK38299.1 - 0.00086 19.5 0.1 0.0027 17.9 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CRK38299.1 - 0.0029 16.8 6.0 0.0044 16.1 1.4 2.1 2 0 0 2 2 2 1 FAD binding domain TrkA_N PF02254.18 CRK38299.1 - 0.053 13.8 1.4 0.094 13.0 0.3 2.0 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox_2 PF07992.14 CRK38299.1 - 0.056 12.7 1.4 0.094 11.9 0.4 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CRK38299.1 - 0.096 11.7 2.1 0.38 9.8 0.7 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_9 PF13454.6 CRK38299.1 - 0.14 12.1 0.4 0.28 11.2 0.4 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 CRK38299.1 - 0.16 11.0 1.8 0.33 9.9 0.2 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein UCR_Fe-S_N PF10399.9 CRK38299.1 - 0.2 11.1 1.2 1 8.8 1.2 2.2 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal SRP40_C PF05022.12 CRK38300.1 - 7e-21 74.9 0.7 7e-21 74.9 0.7 3.7 4 0 0 4 4 4 1 SRP40, C-terminal domain zf-C3HC PF07967.13 CRK38301.1 - 6.3e-39 133.1 2.1 1.8e-34 118.6 1.3 2.4 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.10 CRK38301.1 - 2.3e-26 91.8 1.9 9.5e-26 89.8 0.1 2.4 2 0 0 2 2 2 1 Rsm1-like MMR_HSR1 PF01926.23 CRK38301.1 - 1.6e-08 34.6 0.2 7.8e-08 32.4 0.0 2.3 3 0 0 3 3 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 CRK38301.1 - 0.0006 19.9 0.0 0.002 18.2 0.0 1.8 2 0 0 2 2 2 1 Dynamin family BIR PF00653.21 CRK38301.1 - 0.0022 18.6 0.1 0.054 14.2 0.1 2.5 2 0 0 2 2 2 1 Inhibitor of Apoptosis domain IIGP PF05049.13 CRK38301.1 - 0.0066 15.5 0.0 0.01 14.9 0.0 1.2 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.27 CRK38301.1 - 0.029 14.9 0.0 0.08 13.5 0.0 1.7 1 0 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 CRK38301.1 - 0.03 14.2 0.1 0.057 13.3 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_28 PF13521.6 CRK38301.1 - 0.036 14.3 0.1 0.036 14.3 0.1 2.5 3 0 0 3 3 2 0 AAA domain FeoB_N PF02421.18 CRK38301.1 - 0.047 13.2 0.0 0.082 12.4 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B FtsK_SpoIIIE PF01580.18 CRK38301.1 - 0.11 11.9 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family TniB PF05621.11 CRK38301.1 - 0.11 11.9 0.1 0.89 8.9 0.0 2.1 2 0 0 2 2 2 0 Bacterial TniB protein AAA_21 PF13304.6 CRK38301.1 - 0.12 12.2 0.1 0.32 10.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CRK38301.1 - 0.14 11.9 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_15 PF13175.6 CRK38301.1 - 0.22 11.2 0.0 0.35 10.5 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain DUF4045 PF13254.6 CRK38302.1 - 1.2e-30 107.6 0.6 1.3e-30 107.4 0.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4045) IMS_C PF11799.8 CRK38305.1 - 0.0093 16.7 0.0 0.011 16.4 0.0 1.1 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain Phage_Orf51 PF06194.11 CRK38305.1 - 0.2 11.7 1.0 1.6 8.8 1.0 2.2 1 1 0 1 1 1 0 Phage Conserved Open Reading Frame 51 HSP70 PF00012.20 CRK38306.1 - 1.9e-08 33.0 0.2 1.9e-08 33.0 0.2 1.0 1 0 0 1 1 1 1 Hsp70 protein BACON PF13004.7 CRK38306.1 - 0.029 14.3 0.1 0.033 14.2 0.1 1.2 1 0 0 1 1 1 0 Putative binding domain, N-terminal Peptidase_S58 PF03576.14 CRK38308.1 - 5.4e-109 364.3 3.2 7.7e-72 242.3 0.5 2.2 2 0 0 2 2 2 2 Peptidase family S58 FAR1 PF03101.15 CRK38308.1 - 3.3e-05 24.5 0.0 3.3e-05 24.5 0.0 2.4 2 1 0 2 2 2 1 FAR1 DNA-binding domain BPL_N PF09825.9 CRK38308.1 - 3.7 6.5 11.8 5.5 6.0 11.8 1.2 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal Med15 PF09606.10 CRK38308.1 - 6.5 5.3 55.4 9.4 4.8 55.4 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Fe-ADH PF00465.19 CRK38309.1 - 1.5e-98 330.0 0.1 1.9e-98 329.7 0.1 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 CRK38309.1 - 2.8e-14 53.4 0.0 3.7e-11 43.2 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.6 CRK38309.1 - 0.036 13.7 0.1 0.064 12.9 0.1 1.4 1 0 0 1 1 1 0 Periplasmic binding protein TCP PF03634.13 CRK38310.1 - 0.001 19.6 16.2 0.0012 19.4 16.2 1.1 1 0 0 1 1 1 1 TCP family transcription factor AAA_11 PF13086.6 CRK38310.1 - 0.0021 17.9 7.8 0.0021 17.9 7.8 1.1 1 0 0 1 1 1 1 AAA domain RR_TM4-6 PF06459.12 CRK38310.1 - 0.013 15.3 14.4 0.014 15.2 14.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SLC12 PF03522.15 CRK38310.1 - 0.014 14.5 9.1 0.012 14.6 9.1 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DAG_kinase_N PF14513.6 CRK38310.1 - 0.034 14.4 7.0 0.032 14.4 7.0 1.2 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus RPOL_N PF14700.6 CRK38310.1 - 0.047 13.1 10.6 0.045 13.2 10.6 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal EOS1 PF12326.8 CRK38310.1 - 0.14 12.1 5.3 0.14 12.1 5.3 1.2 1 0 0 1 1 1 0 N-glycosylation protein Med15 PF09606.10 CRK38310.1 - 0.27 9.9 13.6 0.31 9.7 13.6 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Serinc PF03348.15 CRK38310.1 - 0.27 10.1 3.7 0.3 10.0 3.7 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Presenilin PF01080.17 CRK38310.1 - 0.39 9.4 11.8 0.42 9.3 11.8 1.1 1 0 0 1 1 1 0 Presenilin DDHD PF02862.17 CRK38310.1 - 0.51 10.5 8.5 0.61 10.2 8.5 1.2 1 0 0 1 1 1 0 DDHD domain Tim54 PF11711.8 CRK38310.1 - 0.75 8.5 16.6 0.96 8.2 16.6 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Neur_chan_memb PF02932.16 CRK38310.1 - 0.88 9.6 5.7 0.87 9.6 5.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Paramyxo_ncap PF00973.19 CRK38310.1 - 0.96 8.3 6.2 0.99 8.2 6.2 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein CCDC71L PF15374.6 CRK38310.1 - 1 8.5 22.1 1.2 8.4 22.1 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L CDC45 PF02724.14 CRK38310.1 - 4.5 5.4 18.2 5.1 5.3 18.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Sec3_C PF09763.9 CRK38311.1 - 1.1e-35 123.3 0.0 1.4e-35 122.9 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 CRK38311.1 - 7.7e-29 99.7 0.0 1.3e-28 98.9 0.0 1.4 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Tannase PF07519.11 CRK38312.1 - 1.7e-73 248.1 0.0 2.2e-73 247.8 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 CRK38312.1 - 0.019 14.3 0.0 0.037 13.3 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Arteri_Gl PF00951.18 CRK38313.1 - 0.33 10.8 3.0 0.45 10.3 3.0 1.2 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein Apq12 PF12716.7 CRK38313.1 - 1.4 8.9 7.4 5 7.1 1.3 2.7 2 0 0 2 2 2 0 Nuclear pore assembly and biogenesis MFS_1 PF07690.16 CRK38314.1 - 9.4e-13 47.8 25.2 9.4e-13 47.8 25.2 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily EMP70 PF02990.16 CRK38314.1 - 0.94 8.1 11.4 0.13 10.9 6.4 2.0 1 1 1 2 2 2 0 Endomembrane protein 70 RTA1 PF04479.13 CRK38315.1 - 6.2e-07 29.2 5.3 1.3e-06 28.2 5.3 1.5 1 1 0 1 1 1 1 RTA1 like protein DUF4293 PF14126.6 CRK38315.1 - 4.7 7.5 9.2 4.8 7.4 6.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4293) PetM PF08041.11 CRK38315.1 - 4.9 6.8 6.2 16 5.2 0.3 2.9 2 0 0 2 2 2 0 PetM family of cytochrome b6f complex subunit 7 zf-CHY PF05495.12 CRK38318.1 - 3.7e-10 40.2 11.1 3.7e-10 40.2 11.1 3.4 2 1 1 3 3 3 1 CHY zinc finger RWD PF05773.22 CRK38318.1 - 0.0014 18.9 0.0 0.081 13.2 0.0 2.4 2 0 0 2 2 2 1 RWD domain RHINO PF15319.6 CRK38318.1 - 0.0051 16.9 0.5 0.0051 16.9 0.5 1.8 2 0 0 2 2 2 1 RAD9, RAD1, HUS1-interacting nuclear orphan protein DUF3295 PF11702.8 CRK38320.1 - 1.6e-159 532.4 28.7 2.2e-159 532.0 28.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.10 CRK38320.1 - 5e-12 45.4 3.0 9.9e-12 44.5 3.0 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Importin_rep_4 PF18808.1 CRK38320.1 - 0.067 13.5 1.2 0.17 12.2 1.2 1.7 1 0 0 1 1 1 0 Importin repeat VHS PF00790.19 CRK38326.1 - 4.3e-24 85.0 0.0 8.1e-24 84.1 0.0 1.4 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 CRK38326.1 - 1.6e-07 31.5 1.1 3.7e-07 30.3 1.1 1.6 1 0 0 1 1 1 1 GAT domain SR-25 PF10500.9 CRK38326.1 - 0.53 9.8 12.9 0.89 9.1 12.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Nucleoporin_FG PF13634.6 CRK38326.1 - 0.72 10.7 9.0 1.4 9.8 9.0 1.4 1 0 0 1 1 1 0 Nucleoporin FG repeat region HSP70 PF00012.20 CRK38327.1 - 2.9e-260 864.6 14.1 3.3e-260 864.4 14.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CRK38327.1 - 8.1e-17 61.0 1.1 4.3e-15 55.3 0.3 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Hydantoinase_A PF01968.18 CRK38327.1 - 0.0027 17.0 0.7 0.14 11.4 0.0 3.0 2 1 1 3 3 3 1 Hydantoinase/oxoprolinase DUF1464 PF07318.12 CRK38327.1 - 0.023 13.9 0.1 2.1 7.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1464) FtsA PF14450.6 CRK38327.1 - 0.032 14.7 5.6 6.7 7.2 0.5 3.7 3 1 0 3 3 3 0 Cell division protein FtsA Radial_spoke_3 PF06098.11 CRK38327.1 - 0.11 11.8 6.3 0.015 14.6 2.4 1.5 2 0 0 2 2 2 0 Radial spoke protein 3 HEPPP_synt_1 PF07307.11 CRK38327.1 - 0.14 11.7 1.0 0.28 10.7 1.0 1.4 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 GTP_EFTU PF00009.27 CRK38328.1 - 3.6e-44 150.6 0.0 5.5e-44 150.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.10 CRK38328.1 - 6.2e-23 80.9 0.4 1.3e-22 79.9 0.4 1.5 1 0 0 1 1 1 1 HBS1 N-terminus MMR_HSR1 PF01926.23 CRK38328.1 - 3.3e-10 40.1 0.0 4.7e-06 26.6 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU_D3 PF03143.17 CRK38328.1 - 4.2e-07 30.2 0.1 1.1e-06 28.9 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain Roc PF08477.13 CRK38328.1 - 0.0001 22.5 0.2 0.014 15.6 0.0 2.6 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU_D2 PF03144.25 CRK38328.1 - 0.00034 20.9 0.1 0.00084 19.7 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Ras PF00071.22 CRK38328.1 - 0.0037 16.9 0.1 0.12 12.0 0.0 2.3 2 0 0 2 2 2 1 Ras family Septin PF00735.18 CRK38328.1 - 0.0099 15.2 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 1 Septin SRPRB PF09439.10 CRK38328.1 - 0.038 13.4 0.0 1.8 8.0 0.0 2.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 CRK38328.1 - 0.07 12.7 0.1 1.2 8.6 0.1 2.6 2 1 0 2 2 2 0 Ferrous iron transport protein B SmpA_OmlA PF04355.13 CRK38328.1 - 0.16 11.8 0.0 0.38 10.6 0.0 1.6 1 0 0 1 1 1 0 SmpA / OmlA family Cpn60_TCP1 PF00118.24 CRK38329.1 - 7.3e-158 526.2 5.2 8.4e-158 526.0 5.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family His_Phos_1 PF00300.22 CRK38330.1 - 9.9e-15 54.7 0.1 9.9e-14 51.5 0.0 2.2 1 1 1 2 2 2 1 Histidine phosphatase superfamily (branch 1) VHS PF00790.19 CRK38331.1 - 6.2e-21 74.7 4.3 2.4e-17 63.1 0.0 3.2 2 1 1 3 3 3 2 VHS domain FYVE PF01363.21 CRK38331.1 - 1e-14 54.4 4.8 1.7e-14 53.7 4.8 1.3 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.20 CRK38331.1 - 8.7e-06 25.3 15.8 0.0019 18.0 1.5 3.3 3 0 0 3 3 3 2 Ubiquitin interaction motif FYVE_2 PF02318.16 CRK38331.1 - 0.068 13.4 1.7 0.12 12.5 1.7 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger Fer4_2 PF12797.7 CRK38331.1 - 1 9.6 8.2 1.9 8.8 0.2 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain UCH PF00443.29 CRK38332.1 - 7.5e-34 117.4 3.2 1.4e-30 106.7 0.7 2.4 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.20 CRK38332.1 - 3.3e-18 66.1 0.0 1.3e-07 32.1 0.0 2.6 2 0 0 2 2 2 2 Rhodanese-like domain UCH_1 PF13423.6 CRK38332.1 - 1.4e-17 64.2 5.0 1.8e-13 50.8 5.0 3.1 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Cytochrome_C7 PF14522.6 CRK38332.1 - 0.062 13.3 0.1 0.16 12.0 0.1 1.6 1 0 0 1 1 1 0 Cytochrome c7 and related cytochrome c AMP-binding PF00501.28 CRK38333.1 - 6.6e-71 239.1 0.0 4.9e-66 223.1 0.0 2.1 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 CRK38333.1 - 0.045 14.7 0.1 0.33 11.9 0.0 2.4 1 1 1 2 2 2 0 AMP-binding enzyme C-terminal domain PBP_like PF12727.7 CRK38333.1 - 0.12 11.5 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 PBP superfamily domain phiKZ_IP PF12699.7 CRK38333.1 - 0.13 11.4 0.3 3.2 6.8 0.2 2.2 2 0 0 2 2 2 0 phiKZ-like phage internal head proteins KH_1 PF00013.29 CRK38334.1 - 3e-106 347.3 22.6 8.1e-14 51.2 0.0 17.6 18 1 0 18 18 18 12 KH domain SLS PF14611.6 CRK38334.1 - 1.5e-14 54.4 0.5 0.013 15.3 0.0 7.4 4 1 2 7 7 7 3 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.17 CRK38334.1 - 2.6e-13 49.6 21.2 0.037 13.9 0.0 8.3 8 0 0 8 8 8 5 KH domain KH_4 PF13083.6 CRK38334.1 - 2.8e-07 30.3 6.6 0.0085 16.0 0.2 7.2 7 0 0 7 7 7 1 KH domain INTAP PF16617.5 CRK38334.1 - 0.2 12.0 2.8 26 5.2 0.2 3.2 2 0 0 2 2 2 0 Intersectin and clathrin adaptor AP2 binding region DUF5300 PF17224.3 CRK38334.1 - 1.5 9.2 8.0 3.7 7.9 0.0 4.8 5 0 0 5 5 5 0 Domain of unknown function (DUF5300) TFIIE-A_C PF11521.8 CRK38334.1 - 4.6 7.6 10.0 5.9 7.3 0.5 4.1 4 0 0 4 4 4 0 C-terminal general transcription factor TFIIE alpha KH_1 PF00013.29 CRK38335.1 - 8.3e-74 243.4 14.5 4.5e-14 52.0 0.0 8.5 8 1 0 8 8 8 6 KH domain AMP-binding PF00501.28 CRK38335.1 - 1.7e-49 168.6 0.0 3e-49 167.8 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme SLS PF14611.6 CRK38335.1 - 1e-10 41.8 0.1 0.0069 16.2 0.0 4.7 2 1 3 5 5 5 3 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.17 CRK38335.1 - 1.4e-09 37.7 15.8 0.038 13.8 0.4 5.9 6 0 0 6 6 6 4 KH domain DUF5300 PF17224.3 CRK38335.1 - 0.022 15.0 2.5 2.4 8.4 0.0 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF5300) Pkinase PF00069.25 CRK38336.1 - 2.5e-90 302.4 0.0 6.9e-44 150.2 0.0 4.2 3 1 1 4 4 4 4 Protein kinase domain Pkinase_Tyr PF07714.17 CRK38336.1 - 1.6e-52 178.4 0.1 2.1e-25 89.5 0.0 3.9 3 1 1 4 4 4 3 Protein tyrosine kinase PBD PF00786.28 CRK38336.1 - 2.1e-38 130.5 0.1 1.4e-17 63.8 0.0 2.9 2 0 0 2 2 2 2 P21-Rho-binding domain Pkinase_fungal PF17667.1 CRK38336.1 - 4.6e-06 25.7 0.0 1.2e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CRK38336.1 - 1.4e-05 24.6 0.0 6.5e-05 22.4 0.0 2.1 2 0 0 2 2 2 1 Kinase-like DUF1921 PF09081.10 CRK38336.1 - 0.0028 17.8 0.0 5.1 7.4 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF1921) Kdo PF06293.14 CRK38336.1 - 0.049 13.0 0.3 0.44 9.9 0.1 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family ketoacyl-synt PF00109.26 CRK38336.1 - 0.055 13.0 1.1 2.5 7.6 0.1 2.4 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain FemAB PF02388.16 CRK38336.1 - 0.094 11.6 2.5 4.2 6.1 0.0 2.7 3 0 0 3 3 3 0 FemAB family APH PF01636.23 CRK38336.1 - 0.37 10.7 0.0 0.37 10.7 0.0 2.9 3 1 0 3 3 3 0 Phosphotransferase enzyme family adh_short_C2 PF13561.6 CRK38337.1 - 6.2e-62 209.2 0.1 1.1e-61 208.4 0.1 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRK38337.1 - 4e-51 173.2 0.5 6.1e-51 172.7 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CRK38337.1 - 7.1e-12 45.6 0.1 1e-11 45.1 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CRK38337.1 - 5.6e-05 22.7 0.1 0.00011 21.8 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PA PF02225.22 CRK38337.1 - 0.00018 21.5 0.2 0.0014 18.6 0.1 2.2 2 0 0 2 2 2 1 PA domain Polysacc_synt_2 PF02719.15 CRK38337.1 - 0.00028 20.1 0.0 0.0004 19.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 CRK38337.1 - 0.0059 16.0 0.1 0.014 14.8 0.1 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short_C2 PF13561.6 CRK38338.1 - 1.4e-61 208.1 0.1 2.5e-61 207.2 0.1 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRK38338.1 - 7.9e-51 172.3 0.5 1.2e-50 171.7 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CRK38338.1 - 8.8e-12 45.3 0.1 1.2e-11 44.8 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CRK38338.1 - 4.1e-05 23.2 0.1 7.9e-05 22.2 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PA PF02225.22 CRK38338.1 - 0.00016 21.7 0.2 0.0014 18.6 0.1 2.3 2 0 0 2 2 2 1 PA domain Polysacc_synt_2 PF02719.15 CRK38338.1 - 0.00025 20.3 0.0 0.00035 19.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 CRK38338.1 - 0.0078 15.6 0.1 0.018 14.4 0.1 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase SEN1_N PF12726.7 CRK38339.1 - 0.00078 17.8 0.0 0.0011 17.3 0.0 1.1 1 0 0 1 1 1 1 SEN1 N terminal zf-C2H2_4 PF13894.6 CRK38339.1 - 0.1 13.5 0.3 0.1 13.5 0.3 2.8 4 0 0 4 4 4 0 C2H2-type zinc finger zf_ZIC PF18366.1 CRK38339.1 - 4.4 7.5 5.4 11 6.3 0.7 2.4 2 0 0 2 2 2 0 Zic proteins zinc finger domain SEN1_N PF12726.7 CRK38340.1 - 0.0027 16.0 0.2 0.0037 15.5 0.2 1.1 1 0 0 1 1 1 1 SEN1 N terminal zf-C2H2_4 PF13894.6 CRK38340.1 - 0.027 15.3 0.6 0.13 13.2 0.6 2.2 1 0 0 1 1 1 0 C2H2-type zinc finger SelR PF01641.18 CRK38341.1 - 1.5e-47 160.6 0.1 1.9e-47 160.3 0.1 1.1 1 0 0 1 1 1 1 SelR domain DZR PF12773.7 CRK38341.1 - 0.022 14.8 0.3 3.1 7.9 0.0 2.3 2 0 0 2 2 2 0 Double zinc ribbon zinc_ribbon_10 PF10058.9 CRK38341.1 - 0.076 12.8 0.1 0.62 9.8 0.0 2.1 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein ArfGap PF01412.18 CRK38342.1 - 6.4e-39 132.7 0.8 9.6e-39 132.1 0.8 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf partial_CstF PF15861.5 CRK38342.1 - 0.036 13.8 0.1 0.078 12.8 0.1 1.5 1 0 0 1 1 1 0 Partial cleavage stimulation factor domain Synaptobrevin PF00957.21 CRK38343.1 - 0.037 13.8 1.0 0.49 10.2 0.1 2.0 1 1 1 2 2 2 0 Synaptobrevin Phage_holin_2_4 PF16082.5 CRK38343.1 - 0.084 12.6 0.3 0.19 11.5 0.1 1.6 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like Ysc84 PF04366.12 CRK38344.1 - 1.1e-40 138.3 0.6 2.4e-40 137.2 0.6 1.6 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_2 PF07653.17 CRK38344.1 - 6.2e-14 51.4 0.0 1.5e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CRK38344.1 - 2.8e-13 49.2 0.2 1.1e-12 47.3 0.1 2.0 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 CRK38344.1 - 1.4e-12 47.3 0.0 3.1e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain DUF3104 PF11302.8 CRK38344.1 - 0.14 11.9 0.1 0.28 10.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) SH3_2 PF07653.17 CRK38346.1 - 6.7e-14 51.3 0.0 1.3e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CRK38346.1 - 5.7e-13 48.2 0.1 1e-12 47.5 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CRK38346.1 - 1.4e-12 47.2 0.0 2.7e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF3104 PF11302.8 CRK38346.1 - 0.13 12.0 0.1 0.25 11.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) AvrE_T3Es PF11725.8 CRK38347.1 - 1.6 5.8 5.3 1.8 5.7 5.3 1.0 1 0 0 1 1 1 0 AvrE-family Type-III effector proteins (T3Es) Pox_MCEL PF03291.16 CRK38349.1 - 6.4e-65 219.4 0.0 1.9e-46 158.7 0.0 2.3 1 1 1 2 2 2 2 mRNA capping enzyme Methyltransf_25 PF13649.6 CRK38349.1 - 9.5e-11 42.3 0.0 4.3e-05 24.1 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 CRK38349.1 - 3.9e-09 37.2 0.0 0.0025 18.5 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 CRK38349.1 - 1.3e-06 28.9 0.1 0.094 13.4 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 CRK38349.1 - 2.8e-05 24.0 0.0 4.7e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 CRK38349.1 - 6.6e-05 22.2 0.0 0.00011 21.5 0.0 1.3 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_31 PF13847.6 CRK38349.1 - 0.00012 21.9 0.0 0.0021 17.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain RPN7 PF10602.9 CRK38350.1 - 1.1e-54 184.7 0.2 1.6e-54 184.3 0.2 1.2 1 0 0 1 1 1 1 26S proteasome subunit RPN7 Aminotran_1_2 PF00155.21 CRK38351.1 - 6.4e-24 84.8 1.7 2.4e-23 82.9 0.0 2.7 3 1 1 4 4 4 1 Aminotransferase class I and II ZapB PF06005.12 CRK38351.1 - 0.0062 17.0 4.8 0.0062 17.0 4.8 5.9 6 1 0 6 6 6 1 Cell division protein ZapB TetR_C_4 PF08359.11 CRK38351.1 - 0.038 14.1 0.8 0.12 12.5 0.5 2.1 1 1 0 1 1 1 0 YsiA-like protein, C-terminal region DUF3091 PF11291.8 CRK38351.1 - 1.8 8.8 5.5 0.61 10.3 1.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3091) DUF465 PF04325.13 CRK38351.1 - 3.7 7.7 7.8 2.7 8.1 4.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF465) Ribosomal_L33 PF00471.20 CRK38352.1 - 5.8e-05 23.5 0.0 6.1e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L33 DUF2371 PF10177.9 CRK38353.1 - 0.05 13.8 0.0 0.067 13.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) LapA_dom PF06305.11 CRK38353.1 - 0.51 10.2 1.8 0.84 9.5 1.8 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain NUC153 PF08159.12 CRK38354.1 - 1.1e-11 44.3 1.2 2.1e-11 43.4 1.2 1.5 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 CRK38354.1 - 0.0033 18.2 0.1 0.68 10.9 0.0 3.1 4 0 0 4 4 4 1 WD domain, G-beta repeat PLRV_ORF5 PF01690.17 CRK38354.1 - 0.064 12.0 1.8 0.1 11.3 1.8 1.3 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Med13_C PF06333.12 CRK38355.1 - 5.6e-94 315.1 1.7 5.6e-94 315.1 1.7 3.1 5 0 0 5 5 5 1 Mediator complex subunit 13 C-terminal domain Med13_N PF11597.8 CRK38355.1 - 4e-29 102.0 0.3 9.4e-29 100.8 0.3 1.7 1 0 0 1 1 1 1 Mediator complex subunit 13 N-terminal MID_MedPIWI PF18296.1 CRK38355.1 - 3.1e-10 40.3 0.2 0.00014 21.7 0.0 3.0 2 1 1 3 3 3 2 MID domain of medPIWI DUF3147 PF11345.8 CRK38356.1 - 0.013 15.9 0.9 0.013 15.9 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3147) COesterase PF00135.28 CRK38357.1 - 3.6e-77 260.4 0.0 5.2e-77 259.8 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family NAD_binding_10 PF13460.6 CRK38357.1 - 3.5e-16 59.6 0.1 6.8e-16 58.7 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Fungal_trans PF04082.18 CRK38357.1 - 5.1e-13 48.7 0.0 8e-13 48.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK38357.1 - 8e-09 35.5 10.0 1.5e-08 34.6 10.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_3 PF07859.13 CRK38357.1 - 1.2e-05 25.2 0.8 0.00026 20.9 0.1 2.9 2 1 0 2 2 2 1 alpha/beta hydrolase fold zf-RING_5 PF14634.6 CRK38360.1 - 1.3e-08 34.6 5.1 1.8e-08 34.2 5.1 1.2 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CRK38360.1 - 0.012 15.4 6.1 0.047 13.5 6.0 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 CRK38360.1 - 0.014 15.3 8.0 0.12 12.3 8.0 2.1 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CRK38360.1 - 0.11 12.9 4.6 0.4 11.1 4.6 1.9 1 1 0 1 1 1 0 Ring finger domain zf-RING_4 PF14570.6 CRK38360.1 - 0.13 12.0 4.3 0.34 10.8 2.2 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.6 CRK38360.1 - 0.15 11.9 8.4 0.087 12.7 4.6 2.2 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF1002 PF06207.11 CRK38362.1 - 1.1 8.8 7.4 1.5 8.3 7.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1002) Sugar_tr PF00083.24 CRK38370.1 - 1.2e-15 57.3 0.1 1.3e-15 57.3 0.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK38370.1 - 9.2e-08 31.4 0.1 9.2e-08 31.4 0.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily YrhK PF14145.6 CRK38370.1 - 0.0042 16.9 0.5 0.0063 16.4 0.5 1.2 1 0 0 1 1 1 1 YrhK-like protein MFS_2 PF13347.6 CRK38370.1 - 0.0074 14.9 0.2 0.0077 14.8 0.2 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein HSP70 PF00012.20 CRK38378.1 - 1e-17 63.6 1.7 1.4e-17 63.2 1.7 1.1 1 0 0 1 1 1 1 Hsp70 protein Cys_Met_Meta_PP PF01053.20 CRK38379.1 - 8.8e-13 47.5 0.3 1e-12 47.4 0.3 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Het-C PF07217.11 CRK38380.1 - 8.8e-44 150.0 0.1 9.5e-44 149.9 0.1 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Tubulin PF00091.25 CRK38382.1 - 7.7e-19 68.7 0.0 8.6e-19 68.5 0.0 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain RPN1_RPN2_N PF17781.1 CRK38385.1 - 1.6e-81 274.1 0.1 1.8e-81 274.0 0.1 1.0 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain MatE PF01554.18 CRK38385.1 - 1.7e-10 40.7 0.7 4.3e-10 39.5 0.6 1.7 2 0 0 2 2 2 1 MatE Herpes_UL95 PF03038.14 CRK38385.1 - 0.017 14.2 0.1 0.025 13.7 0.1 1.1 1 0 0 1 1 1 0 UL95 family Nop16 PF09420.10 CRK38386.1 - 8.9e-30 104.3 4.0 9.6e-30 104.2 4.0 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 ABC_tran_Xtn PF12848.7 CRK38386.1 - 0.0081 16.2 6.5 0.01 15.9 6.5 1.2 1 0 0 1 1 1 1 ABC transporter HTH_38 PF13936.6 CRK38386.1 - 0.017 14.9 0.3 1.3 8.9 0.0 2.4 1 1 1 2 2 2 0 Helix-turn-helix domain Aha1_N PF09229.11 CRK38389.1 - 4.9e-29 101.3 0.2 7.9e-29 100.6 0.2 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 CRK38389.1 - 7.9e-20 71.3 0.2 1.4e-19 70.6 0.2 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein SH3BGR PF04908.15 CRK38389.1 - 0.22 11.7 0.7 19 5.5 0.1 2.8 2 1 1 3 3 3 0 SH3-binding, glutamic acid-rich protein RTA1 PF04479.13 CRK38390.1 - 1.2e-23 83.8 0.4 1.3e-23 83.7 0.4 1.0 1 0 0 1 1 1 1 RTA1 like protein DUF1569 PF07606.11 CRK38391.1 - 0.11 12.5 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1569) AATF-Che1 PF13339.6 CRK38393.1 - 5.2e-13 49.9 0.0 5.2e-13 49.9 0.0 2.9 2 1 0 2 2 2 1 Apoptosis antagonizing transcription factor AAA_21 PF13304.6 CRK38393.1 - 0.18 11.5 3.3 0.15 11.8 1.2 1.8 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Fungal_trans PF04082.18 CRK38394.1 - 3.5e-12 45.9 0.2 8.3e-12 44.7 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK38394.1 - 1.6e-08 34.6 8.7 2.9e-08 33.7 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain P63C PF10546.9 CRK38394.1 - 0.048 14.2 1.7 0.2 12.3 0.2 2.6 1 1 2 3 3 3 0 P63C domain HalX PF08663.10 CRK38394.1 - 0.05 13.9 0.6 0.11 12.9 0.6 1.5 1 0 0 1 1 1 0 HalX domain DASH_Dad3 PF08656.10 CRK38394.1 - 1.9 8.7 5.1 6.2 7.0 0.6 2.7 2 1 0 2 2 2 0 DASH complex subunit Dad3 Pyr_redox_2 PF07992.14 CRK38395.1 - 3.6e-39 134.8 0.1 4.8e-39 134.3 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CRK38395.1 - 2.9e-12 47.0 0.5 3.1e-11 43.7 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CRK38395.1 - 1.9e-05 24.1 0.0 4.1e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CRK38395.1 - 0.0002 20.6 0.1 0.00079 18.7 0.1 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 CRK38395.1 - 0.0006 19.5 1.0 2.1 7.8 0.0 3.9 4 0 0 4 4 4 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CRK38395.1 - 0.0014 17.8 0.5 0.78 8.7 0.1 2.8 3 0 0 3 3 3 2 FAD binding domain Trp_halogenase PF04820.14 CRK38395.1 - 0.0015 17.4 0.5 0.9 8.3 0.4 2.7 2 1 0 2 2 2 2 Tryptophan halogenase Thi4 PF01946.17 CRK38395.1 - 0.0074 15.6 0.0 0.95 8.6 0.0 2.3 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.6 CRK38395.1 - 0.0097 15.9 0.6 12 5.8 0.1 4.1 3 1 1 4 4 4 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 CRK38395.1 - 0.011 16.0 0.2 4.5 7.6 0.0 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 CRK38395.1 - 0.012 14.7 0.3 0.16 11.0 0.0 2.8 4 0 0 4 4 4 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 CRK38395.1 - 0.019 14.3 0.2 1.3 8.3 0.1 2.6 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 CRK38395.1 - 0.031 13.0 0.9 0.3 9.7 0.1 2.7 3 0 0 3 3 3 0 HI0933-like protein GIDA PF01134.22 CRK38395.1 - 4.2 6.4 8.2 0.91 8.5 0.5 3.0 3 1 0 3 3 3 0 Glucose inhibited division protein A Acetyltransf_1 PF00583.25 CRK38396.1 - 1.7e-05 25.0 0.0 3.7e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CRK38396.1 - 0.001 19.0 0.1 0.0034 17.3 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CRK38396.1 - 0.0036 17.7 0.0 0.0072 16.7 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain AIRC PF00731.20 CRK38397.1 - 2e-12 46.9 0.0 2.4e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 AIR carboxylase DUF3807 PF12720.7 CRK38398.1 - 2.6 8.3 22.2 1.6 8.9 5.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) YjbH PF06082.11 CRK38398.1 - 7.8 5.2 11.3 8.8 5.0 11.3 1.0 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH Pescadillo_N PF06732.11 CRK38400.1 - 2.6e-31 109.2 0.0 2.7e-31 109.1 0.0 1.0 1 0 0 1 1 1 1 Pescadillo N-terminus GrpE PF01025.19 CRK38402.1 - 0.41 10.3 6.7 0.75 9.4 6.7 1.6 1 1 0 1 1 1 0 GrpE DivIC PF04977.15 CRK38402.1 - 3.1 7.6 6.7 0.49 10.2 2.5 1.8 1 1 1 2 2 2 0 Septum formation initiator Cnn_1N PF07989.11 CRK38403.1 - 9.7e-22 76.9 7.6 9.7e-22 76.9 7.6 10.7 8 1 3 11 11 11 2 Centrosomin N-terminal motif 1 ERM PF00769.19 CRK38403.1 - 0.00058 19.8 133.1 0.0051 16.7 23.1 6.5 1 1 4 5 5 5 2 Ezrin/radixin/moesin family EzrA PF06160.12 CRK38403.1 - 0.0015 16.8 37.7 0.0015 16.8 37.7 4.8 2 2 2 5 5 5 1 Septation ring formation regulator, EzrA DegS PF05384.11 CRK38403.1 - 0.0069 15.9 3.0 0.0069 15.9 3.0 7.6 3 1 4 7 7 7 1 Sensor protein DegS TPR_MLP1_2 PF07926.12 CRK38403.1 - 0.009 16.1 19.3 0.009 16.1 19.3 8.8 4 2 5 10 10 10 3 TPR/MLP1/MLP2-like protein Vip3A_N PF12495.8 CRK38403.1 - 0.49 10.3 1.6 1.7 8.5 0.1 2.6 3 0 0 3 3 3 0 Vegetative insecticide protein 3A N terminal NPV_P10 PF05531.12 CRK38403.1 - 0.58 10.7 0.0 0.58 10.7 0.0 6.6 4 1 3 7 7 7 0 Nucleopolyhedrovirus P10 protein DUF2935 PF11155.8 CRK38403.1 - 1.3 9.4 12.6 3.1 8.1 1.0 4.8 3 3 0 3 3 3 0 Domain of unknown function (DUF2935) Fib_alpha PF08702.10 CRK38403.1 - 4.1 7.6 67.1 0.4 10.9 3.7 7.9 4 2 5 9 9 9 0 Fibrinogen alpha/beta chain family RNase_PH PF01138.21 CRK38404.1 - 2.2e-13 50.8 0.0 2.6e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 UCH PF00443.29 CRK38406.1 - 2.2e-09 37.2 0.0 2.5e-09 37.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Sec10 PF07393.11 CRK38406.1 - 0.27 9.6 0.0 0.3 9.5 0.0 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec10 HIT PF01230.23 CRK38409.1 - 1.5e-06 28.9 0.0 1.6e-06 28.7 0.0 1.1 1 0 0 1 1 1 1 HIT domain SelA PF03841.13 CRK38409.1 - 0.097 11.6 0.0 0.1 11.6 0.0 1.1 1 0 0 1 1 1 0 L-seryl-tRNA selenium transferase Brix PF04427.18 CRK38424.1 - 1.5e-31 110.0 0.3 1.9e-31 109.7 0.3 1.2 1 0 0 1 1 1 1 Brix domain UPF1_Zn_bind PF09416.10 CRK38426.1 - 1.8e-71 239.1 2.0 6.4e-71 237.2 1.0 2.1 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 CRK38426.1 - 2.6e-59 200.2 0.0 4.8e-59 199.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CRK38426.1 - 1.5e-52 179.0 3.1 4.4e-29 102.1 0.3 2.2 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 CRK38426.1 - 1.1e-31 108.9 0.0 2e-31 108.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 CRK38426.1 - 4.6e-14 52.6 0.7 8.7e-13 48.4 0.7 2.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CRK38426.1 - 1e-09 38.9 0.1 3.4e-09 37.2 0.1 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 CRK38426.1 - 5.7e-06 26.4 0.0 1.1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PIF1 PF05970.14 CRK38426.1 - 0.00018 20.8 0.1 0.13 11.4 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase DUF2075 PF09848.9 CRK38426.1 - 0.00029 20.2 0.1 0.0053 16.1 0.0 2.5 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 CRK38426.1 - 0.0005 20.0 0.0 0.00096 19.0 0.0 1.5 1 0 0 1 1 1 1 Helicase DEAD PF00270.29 CRK38426.1 - 0.002 17.9 0.3 0.0044 16.8 0.2 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase Viral_helicase1 PF01443.18 CRK38426.1 - 0.0027 17.5 0.1 2.5 7.8 0.0 2.9 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase ATPase PF06745.13 CRK38426.1 - 0.0072 15.7 0.0 0.017 14.5 0.0 1.6 2 0 0 2 2 2 1 KaiC UvrD-helicase PF00580.21 CRK38426.1 - 0.014 14.9 0.1 0.066 12.7 0.1 2.0 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_10 PF12846.7 CRK38426.1 - 0.033 13.1 0.0 0.055 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain SRP54 PF00448.22 CRK38426.1 - 0.037 13.6 0.0 0.067 12.8 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_16 PF13191.6 CRK38426.1 - 0.059 13.7 0.6 0.12 12.8 0.1 1.7 2 0 0 2 2 1 0 AAA ATPase domain PhoH PF02562.16 CRK38426.1 - 0.092 12.2 0.0 0.24 10.8 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein AAA_22 PF13401.6 CRK38426.1 - 0.1 12.9 0.1 0.42 10.9 0.0 2.0 2 0 0 2 2 1 0 AAA domain Glyco_hydro_47 PF01532.20 CRK38427.1 - 7.8e-169 562.4 0.6 1e-168 562.0 0.1 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 47 DHHA2 PF02833.14 CRK38427.1 - 4.6e-13 49.6 0.1 8.8e-13 48.6 0.1 1.4 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 CRK38427.1 - 1.2e-06 28.7 0.0 2.8e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 DHH family Dicty_REP PF05086.12 CRK38427.1 - 3.5 5.5 5.3 5.7 4.8 5.3 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DnaJ PF00226.31 CRK38428.1 - 2.1e-21 75.8 0.4 2.8e-21 75.4 0.4 1.2 1 0 0 1 1 1 1 DnaJ domain Porin_3 PF01459.22 CRK38429.1 - 2.7e-38 132.0 4.4 2.9e-28 99.1 0.6 2.0 2 0 0 2 2 2 2 Eukaryotic porin Asn_synthase PF00733.21 CRK38430.1 - 5.9e-68 230.1 1.4 2.1e-37 129.6 0.2 2.0 1 1 1 2 2 2 2 Asparagine synthase GATase_6 PF13522.6 CRK38430.1 - 0.029 14.6 0.0 0.053 13.7 0.0 1.3 1 0 0 1 1 1 0 Glutamine amidotransferase domain UQ_con PF00179.26 CRK38431.1 - 3.9e-49 165.9 0.1 4.4e-49 165.7 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CRK38431.1 - 4.9e-05 23.0 0.0 5.3e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 CRK38431.1 - 0.01 16.1 1.9 0.024 14.9 1.9 1.8 1 1 0 1 1 1 0 RWD domain Pex19 PF04614.12 CRK38432.1 - 3.2e-78 262.9 11.5 3.2e-78 262.9 11.5 1.5 2 0 0 2 2 2 1 Pex19 protein family PP2C_C PF07830.13 CRK38432.1 - 0.22 12.0 1.1 14 6.2 0.0 3.1 3 1 0 3 3 3 0 Protein serine/threonine phosphatase 2C, C-terminal domain GET2 PF08690.10 CRK38432.1 - 0.74 9.4 18.9 0.11 12.2 9.6 3.1 1 1 1 3 3 3 0 GET complex subunit GET2 FKBP_N PF01346.18 CRK38432.1 - 3.8 8.5 10.3 17 6.5 3.2 3.3 1 1 1 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Ribosomal_L36e PF01158.18 CRK38433.1 - 0.053 13.8 0.5 0.085 13.1 0.5 1.3 1 0 0 1 1 1 0 Ribosomal protein L36e NFACT-R_1 PF05670.13 CRK38433.1 - 0.09 13.4 0.1 0.14 12.8 0.1 1.3 1 0 0 1 1 1 0 NFACT protein RNA binding domain ABC1 PF03109.16 CRK38434.1 - 1.7e-32 112.1 0.0 2.9e-32 111.3 0.0 1.4 1 0 0 1 1 1 1 ABC1 family Rad52_Rad22 PF04098.15 CRK38435.1 - 1.5e-60 203.5 0.0 2.2e-60 203.0 0.0 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein Cut8 PF08559.10 CRK38436.1 - 4.4e-75 252.4 0.0 5.5e-75 252.1 0.0 1.1 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein RRM_1 PF00076.22 CRK38437.1 - 1.9e-16 59.6 0.2 4.5e-10 39.2 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CRK38437.1 - 0.0007 19.7 0.1 0.013 15.6 0.1 2.3 2 0 0 2 2 2 1 RNA recognition motif Nup35_RRM_2 PF14605.6 CRK38437.1 - 0.069 13.2 0.0 0.76 9.8 0.0 2.2 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RsmJ PF04378.13 CRK38437.1 - 0.094 11.9 0.2 0.16 11.2 0.2 1.4 1 0 0 1 1 1 0 Ribosomal RNA large subunit methyltransferase D, RlmJ RPA43_OB PF17875.1 CRK38437.1 - 2 9.1 14.5 2.5 8.7 0.7 2.8 3 0 0 3 3 3 0 RPA43 OB domain in RNA Pol I Gln-synt_C PF00120.24 CRK38438.1 - 4.6e-57 193.6 0.0 1.4e-38 132.8 0.0 2.2 1 1 1 2 2 2 2 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.14 CRK38438.1 - 6.1e-15 55.8 0.0 1.3e-14 54.7 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase Gln-synt_N_2 PF16952.5 CRK38438.1 - 0.0011 18.8 0.0 0.0026 17.6 0.0 1.6 1 0 0 1 1 1 1 Glutamine synthetase N-terminal domain But2 PF09792.9 CRK38439.1 - 0.00043 20.7 0.0 0.00099 19.5 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain Glyco_hydro_76 PF03663.14 CRK38440.1 - 1.5e-167 557.8 8.2 1.9e-161 537.6 10.1 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 CRK38440.1 - 0.023 13.8 0.6 0.023 13.8 0.6 3.9 4 1 1 5 5 5 0 Glycosyl Hydrolase Family 88 DUF3624 PF12292.8 CRK38440.1 - 0.35 11.3 2.5 9.2 6.8 0.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3624) MFS_1 PF07690.16 CRK38441.1 - 8.7e-33 113.7 34.7 8.7e-33 113.7 34.7 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK38441.1 - 0.0033 16.3 19.7 0.0098 14.8 19.6 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter UNC-93 PF05978.16 CRK38441.1 - 0.12 12.1 3.5 0.29 10.8 3.5 1.7 1 0 0 1 1 1 0 Ion channel regulatory protein UNC-93 zf-C2H2 PF00096.26 CRK38442.1 - 0.00017 21.9 13.0 0.068 13.7 2.3 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CRK38442.1 - 0.017 15.9 10.3 3.8 8.6 1.3 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger DUF3450 PF11932.8 CRK38442.1 - 0.02 14.2 1.3 0.029 13.7 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) ZapB PF06005.12 CRK38442.1 - 0.021 15.2 1.3 0.044 14.2 1.3 1.5 1 0 0 1 1 1 0 Cell division protein ZapB HAUS5 PF14817.6 CRK38442.1 - 0.035 12.9 0.9 0.044 12.5 0.9 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 zf-C2H2_aberr PF17017.5 CRK38442.1 - 0.056 13.6 0.3 0.49 10.5 0.0 2.2 2 0 0 2 2 2 0 Aberrant zinc-finger GAS PF13851.6 CRK38442.1 - 0.08 12.3 2.4 0.12 11.7 2.4 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding CDPS PF16715.5 CRK38442.1 - 0.11 12.1 0.4 0.17 11.5 0.4 1.2 1 0 0 1 1 1 0 Cyclodipeptide synthase SHE3 PF17078.5 CRK38442.1 - 0.23 11.1 2.8 0.35 10.5 2.8 1.2 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 UPF0242 PF06785.11 CRK38442.1 - 0.3 11.2 1.1 0.44 10.6 1.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus HalX PF08663.10 CRK38442.1 - 0.44 10.9 3.5 0.53 10.6 1.9 2.0 2 1 1 3 3 3 0 HalX domain zf-H2C2_2 PF13465.6 CRK38442.1 - 6.7 7.3 15.7 20 5.8 0.0 3.8 3 1 0 3 3 3 0 Zinc-finger double domain ATG16 PF08614.11 CRK38443.1 - 2.5e-05 24.6 12.0 2.5e-05 24.6 12.0 4.0 2 2 1 3 3 3 1 Autophagy protein 16 (ATG16) TSC22 PF01166.18 CRK38443.1 - 3.7e-05 24.0 12.6 0.01 16.1 0.2 4.4 4 0 0 4 4 4 2 TSC-22/dip/bun family Filament PF00038.21 CRK38443.1 - 0.00016 21.3 10.4 0.00016 21.3 10.4 4.7 2 1 3 5 5 5 1 Intermediate filament protein Band_7 PF01145.25 CRK38443.1 - 0.077 13.0 1.2 0.23 11.5 1.2 1.7 1 0 0 1 1 1 0 SPFH domain / Band 7 family bZIP_1 PF00170.21 CRK38443.1 - 0.1 12.7 36.6 0.48 10.5 0.7 6.1 5 1 1 6 6 6 0 bZIP transcription factor HALZ PF02183.18 CRK38443.1 - 0.11 12.7 0.2 0.11 12.7 0.2 4.9 5 0 0 5 5 5 0 Homeobox associated leucine zipper Scaffolding_pro PF11418.8 CRK38443.1 - 0.11 13.0 0.3 0.11 13.0 0.3 2.5 3 0 0 3 3 3 0 Phi29 scaffolding protein Shugoshin_N PF07558.11 CRK38443.1 - 2.4 8.1 13.9 2.5 8.1 0.4 4.4 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region CCDC92 PF14916.6 CRK38443.1 - 7.4 6.4 6.9 3.6 7.4 0.0 3.5 4 0 0 4 4 4 0 Coiled-coil domain of unknown function DUF5308 PF17233.2 CRK38444.1 - 1e-54 185.2 29.3 1.8e-53 181.2 29.3 2.4 1 1 0 1 1 1 1 Family of unknown function (DUF5308) Transketolase_N PF00456.21 CRK38445.1 - 7.1e-156 518.3 0.0 1e-155 517.8 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 CRK38445.1 - 1.2e-44 152.1 0.0 1.9e-44 151.4 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 CRK38445.1 - 8e-14 51.6 0.0 1.5e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 CRK38445.1 - 0.0063 15.8 0.0 0.01 15.1 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Methyltransf_34 PF11312.8 CRK38446.1 - 3.4e-106 354.9 0.0 3.9e-106 354.7 0.0 1.0 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase Syja_N PF02383.18 CRK38447.1 - 1.7e-94 316.8 0.0 2.2e-94 316.4 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 CRK38447.1 - 5.3e-40 135.7 0.0 1.1e-39 134.7 0.0 1.6 1 0 0 1 1 1 1 Inositol phosphatase DUF1543 PF07566.12 CRK38447.1 - 0.18 11.6 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1543) FA_hydroxylase PF04116.13 CRK38448.1 - 1.4e-22 80.5 21.5 3.2e-22 79.3 17.7 2.1 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily Ribosomal_L7Ae PF01248.26 CRK38449.1 - 9.2e-25 86.2 0.2 1.1e-24 86.0 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 CRK38449.1 - 0.00025 21.1 0.0 0.00031 20.8 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.6 CRK38449.1 - 0.00036 20.4 0.0 0.00047 20.0 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain ATP-synt_C PF00137.21 CRK38450.1 - 8e-35 119.0 34.8 5.6e-22 77.8 15.6 2.1 2 0 0 2 2 2 2 ATP synthase subunit C ERG4_ERG24 PF01222.17 CRK38451.1 - 2.1e-137 458.4 18.3 2.6e-137 458.1 18.3 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Translin PF01997.16 CRK38452.1 - 5.9e-48 163.6 0.0 6.9e-48 163.3 0.0 1.0 1 0 0 1 1 1 1 Translin family Fusion_F0 PF13044.6 CRK38452.1 - 0.019 13.7 0.0 0.026 13.2 0.0 1.1 1 0 0 1 1 1 0 Fusion glycoprotein F0, Isavirus Pkinase PF00069.25 CRK38453.1 - 2.5e-71 240.1 0.0 5.3e-71 239.1 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK38453.1 - 5.1e-49 166.9 0.0 8.5e-49 166.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CRK38453.1 - 1.7e-05 23.8 0.0 3.3e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CRK38453.1 - 0.0089 15.4 0.0 0.08 12.2 0.1 2.1 2 0 0 2 2 2 1 Kinase-like DUF218 PF02698.17 CRK38455.1 - 0.00016 21.7 0.0 0.00022 21.2 0.0 1.3 1 0 0 1 1 1 1 DUF218 domain Abhydrolase_6 PF12697.7 CRK38456.1 - 3.5e-05 24.5 0.1 6.8e-05 23.6 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CRK38456.1 - 0.0052 16.1 0.4 1.9 7.7 0.0 2.4 2 1 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 CRK38456.1 - 0.0054 16.2 0.0 0.19 11.2 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family ICE2 PF08426.10 CRK38457.1 - 1.7e-155 518.2 6.2 1.9e-155 518.0 6.2 1.0 1 0 0 1 1 1 1 ICE2 FA_desaturase PF00487.24 CRK38458.1 - 8.5e-28 97.9 12.9 1.2e-27 97.4 12.9 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 CRK38458.1 - 4.2e-18 64.5 0.5 7.9e-18 63.7 0.5 1.5 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Motile_Sperm PF00635.26 CRK38459.1 - 1.5e-24 85.9 0.4 3e-24 85.0 0.3 1.6 1 1 0 1 1 1 1 MSP (Major sperm protein) domain ASH PF15780.5 CRK38459.1 - 0.00052 20.2 0.2 0.0019 18.3 0.2 2.0 1 1 1 2 2 2 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin FixG_C PF11614.8 CRK38459.1 - 0.0019 18.4 0.6 0.0097 16.1 0.0 2.1 2 0 0 2 2 2 1 IG-like fold at C-terminal of FixG, putative oxidoreductase DUF2408 PF10303.9 CRK38460.1 - 8.3e-24 84.7 34.7 4.2e-15 56.5 0.4 6.5 4 4 1 5 5 5 4 Protein of unknown function (DUF2408) UBA PF00627.31 CRK38460.1 - 0.00025 20.9 0.0 0.00087 19.1 0.0 2.0 1 0 0 1 1 1 1 UBA/TS-N domain Ribosomal_60s PF00428.19 CRK38461.1 - 7.3e-28 97.0 10.4 8.9e-28 96.7 10.4 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein YCII PF03795.14 CRK38462.1 - 1.8e-08 34.7 0.0 2.3e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 YCII-related domain Mito_carr PF00153.27 CRK38463.1 - 8.6e-60 198.7 2.7 1.9e-21 75.8 0.0 3.8 2 2 1 3 3 3 3 Mitochondrial carrier protein AhpC-TSA PF00578.21 CRK38463.1 - 9.3e-23 80.5 0.0 1.8e-22 79.5 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CRK38463.1 - 5.1e-13 49.0 0.0 9.5e-13 48.1 0.0 1.4 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 CRK38463.1 - 0.14 12.2 0.0 0.39 10.9 0.0 1.7 1 1 0 1 1 1 0 AhpC/TSA antioxidant enzyme UCR_14kD PF02271.16 CRK38465.1 - 6.6e-43 144.8 0.2 8e-43 144.5 0.2 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Anp1 PF03452.14 CRK38466.1 - 5.5e-102 340.7 0.1 1.2e-98 329.7 0.1 2.1 1 1 0 1 1 1 1 Anp1 HhH-GPD PF00730.25 CRK38468.1 - 1.8e-14 54.1 0.0 4.1e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein zf-RNPHF PF08080.12 CRK38469.1 - 0.042 13.8 0.3 0.17 11.9 0.0 2.0 2 0 0 2 2 2 0 RNPHF zinc finger Recep_L_domain PF01030.24 CRK38470.1 - 0.0002 21.5 1.1 3.4 7.8 0.0 4.0 2 2 1 3 3 3 3 Receptor L domain Ecm33 PF12454.8 CRK38470.1 - 0.0034 17.5 2.9 0.0034 17.5 2.9 2.1 2 0 0 2 2 2 1 GPI-anchored cell wall organization protein G-patch PF01585.23 CRK38471.1 - 6.7e-10 38.7 0.2 1.6e-09 37.5 0.2 1.6 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 CRK38471.1 - 0.0075 16.1 0.1 0.019 14.8 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AMP-binding PF00501.28 CRK38472.1 - 7.4e-84 281.8 0.0 8.8e-84 281.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CRK38472.1 - 2.1e-18 67.1 0.1 4.3e-18 66.1 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.13 CRK38472.1 - 6.7e-05 21.9 0.1 0.0023 16.9 0.0 2.6 2 1 1 3 3 3 1 GH3 auxin-responsive promoter RTX_C PF08339.10 CRK38472.1 - 0.01 15.9 0.0 0.036 14.1 0.0 1.9 1 1 1 2 2 2 0 RTX C-terminal domain DUF676 PF05057.14 CRK38473.1 - 3.5e-53 180.4 0.0 4.9e-53 179.9 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 CRK38473.1 - 1.4e-05 25.1 0.0 2e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 CRK38473.1 - 0.00085 19.1 0.0 0.011 15.5 0.0 2.3 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 CRK38473.1 - 0.005 17.5 0.0 0.022 15.4 0.0 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 CRK38473.1 - 0.02 14.7 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Podoplanin PF05808.11 CRK38474.1 - 0.14 12.3 2.9 0.34 11.0 2.9 1.7 1 0 0 1 1 1 0 Podoplanin RAP1 PF07218.11 CRK38474.1 - 0.53 8.5 6.1 0.73 8.1 6.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Band_7 PF01145.25 CRK38475.1 - 3.2e-13 50.1 9.6 8.2e-13 48.7 9.6 1.6 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 CRK38475.1 - 0.00014 21.1 5.7 0.00017 20.8 5.7 1.1 1 0 0 1 1 1 1 SigmaW regulon antibacterial Band_7_1 PF13421.6 CRK38475.1 - 0.088 12.5 0.1 0.13 12.0 0.1 1.2 1 0 0 1 1 1 0 SPFH domain-Band 7 family AMP-binding_C PF13193.6 CRK38476.1 - 3.6e-19 69.5 0.1 6e-19 68.8 0.1 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 CRK38476.1 - 6.2e-19 67.9 0.0 9.5e-19 67.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme RTX_C PF08339.10 CRK38476.1 - 0.00092 19.3 0.1 0.0065 16.5 0.0 2.2 2 1 1 3 3 3 1 RTX C-terminal domain DUF676 PF05057.14 CRK38477.1 - 5.5e-53 179.7 0.0 7.6e-53 179.2 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 CRK38477.1 - 1.4e-05 25.1 0.0 2.1e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.7 CRK38477.1 - 0.00072 20.2 0.0 0.0032 18.1 0.0 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.13 CRK38477.1 - 0.0016 18.2 0.0 0.025 14.3 0.0 2.3 1 1 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.25 CRK38477.1 - 0.031 14.1 0.0 0.052 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Lipase_2 PF01674.18 CRK38477.1 - 0.089 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 2) RAP1 PF07218.11 CRK38478.1 - 0.025 12.9 4.4 0.034 12.4 4.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) FAM199X PF15814.5 CRK38478.1 - 0.68 8.9 5.0 1.4 7.9 5.0 1.5 1 0 0 1 1 1 0 Protein family FAM199X Band_7 PF01145.25 CRK38479.1 - 4.7e-25 88.6 19.5 4.7e-23 82.1 6.0 2.6 1 1 1 2 2 2 2 SPFH domain / Band 7 family YdfA_immunity PF12127.8 CRK38479.1 - 0.0014 17.8 5.9 0.0014 17.8 5.9 2.1 1 1 1 2 2 2 2 SigmaW regulon antibacterial DUF3255 PF11631.8 CRK38479.1 - 0.016 15.1 0.0 3.1 7.7 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3255) HrpA_pilin PF09589.10 CRK38479.1 - 0.15 12.8 16.5 7.5 7.3 3.8 3.6 2 1 0 3 3 3 0 HrpA pilus formation protein Methyltransf_5 PF01795.19 CRK38479.1 - 0.4 10.1 11.7 0.78 9.2 1.7 2.5 1 1 1 2 2 2 0 MraW methylase family CCDC50_N PF15295.6 CRK38479.1 - 0.85 9.8 19.1 1.4 9.1 3.2 2.5 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 50 N-terminus Atg14 PF10186.9 CRK38479.1 - 0.94 8.5 6.6 1.5 7.9 0.7 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Bot1p PF12298.8 CRK38479.1 - 1.7 8.8 7.1 4.2 7.5 1.3 2.2 2 0 0 2 2 2 0 Eukaryotic mitochondrial regulator protein Atg8 PF02991.16 CRK38479.1 - 2.9 8.1 5.2 28 4.9 0.5 2.5 2 0 0 2 2 2 0 Autophagy protein Atg8 ubiquitin like UcrQ PF02939.16 CRK38480.1 - 5.7e-33 112.7 0.4 1.4e-32 111.4 0.1 1.8 2 0 0 2 2 2 1 UcrQ family Ribosomal_L7Ae PF01248.26 CRK38480.1 - 3.3e-18 65.2 0.4 1.4e-17 63.2 0.4 1.9 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Connexin PF00029.19 CRK38480.1 - 0.083 12.6 0.6 0.13 12.0 0.6 1.2 1 0 0 1 1 1 0 Connexin Eapp_C PF10238.9 CRK38480.1 - 0.15 12.1 1.1 0.22 11.6 1.1 1.3 1 0 0 1 1 1 0 E2F-associated phosphoprotein SR-25 PF10500.9 CRK38480.1 - 1 8.9 13.7 0.38 10.3 9.2 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein UcrQ PF02939.16 CRK38481.1 - 3.8e-32 110.1 0.1 4.6e-32 109.8 0.1 1.1 1 0 0 1 1 1 1 UcrQ family Ribosomal_L7Ae PF01248.26 CRK38482.1 - 1.2e-20 73.0 0.5 5.8e-20 70.8 0.5 2.0 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF1761 PF08570.10 CRK38483.1 - 2.4e-25 89.2 4.6 2.8e-25 89.0 4.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) NIF PF03031.18 CRK38484.1 - 9.8e-56 187.9 0.0 1.4e-55 187.3 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase XRCC4 PF06632.12 CRK38484.1 - 0.79 8.5 7.5 2.3 7.0 4.4 2.0 2 0 0 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 IF-2B PF01008.17 CRK38486.1 - 3.2e-74 249.7 2.7 5.6e-40 137.3 0.3 2.8 2 1 0 2 2 2 2 Initiation factor 2 subunit family THOC7 PF05615.13 CRK38486.1 - 0.042 14.1 0.1 17 5.7 0.0 2.4 2 0 0 2 2 2 0 Tho complex subunit 7 zf-C2H2_6 PF13912.6 CRK38486.1 - 0.1 12.6 0.9 18 5.5 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger RepB_primase PF16793.5 CRK38486.1 - 0.13 12.3 1.6 15 5.6 0.1 2.3 2 0 0 2 2 2 0 RepB DNA-primase from phage plasmid Rota_Capsid_VP6 PF00980.17 CRK38486.1 - 0.2 10.5 0.2 18 4.1 0.0 2.1 2 0 0 2 2 2 0 Rotavirus major capsid protein VP6 RPN5_C PF18098.1 CRK38486.1 - 1.4 9.1 5.2 92 3.3 0.3 3.9 3 0 0 3 3 3 0 26S proteasome regulatory subunit RPN5 C-terminal domain ATP-synt_C PF00137.21 CRK38486.1 - 2.7 8.4 6.5 34 4.9 0.5 3.1 3 0 0 3 3 3 0 ATP synthase subunit C Acetyltransf_1 PF00583.25 CRK38487.1 - 1.9e-10 41.0 0.0 2.8e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 CRK38487.1 - 4.5e-06 26.5 0.0 7.2e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 CRK38487.1 - 3.3e-05 23.8 0.0 4.9e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CRK38487.1 - 8.1e-05 23.0 0.0 0.00014 22.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CRK38487.1 - 0.048 13.7 0.1 0.09 12.9 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain adh_short_C2 PF13561.6 CRK38488.1 - 8e-43 146.7 0.1 4e-40 137.8 0.0 2.2 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRK38488.1 - 3.8e-42 143.9 0.1 6.5e-42 143.2 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase HhH-GPD PF00730.25 CRK38488.1 - 1.4e-17 64.1 0.0 2.5e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein KR PF08659.10 CRK38488.1 - 9.6e-14 51.7 0.1 1.9e-13 50.7 0.1 1.4 1 0 0 1 1 1 1 KR domain HHH PF00633.23 CRK38488.1 - 1.5e-07 30.9 0.0 4.1e-07 29.5 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif Epimerase PF01370.21 CRK38488.1 - 0.00086 18.8 0.1 0.0035 16.8 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family HHH_5 PF14520.6 CRK38488.1 - 0.056 14.0 0.2 0.92 10.2 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix domain SPOR PF05036.13 CRK38488.1 - 0.14 12.6 0.0 23 5.5 0.0 2.5 2 0 0 2 2 2 0 Sporulation related domain zf-AN1 PF01428.16 CRK38489.1 - 1.6e-12 47.4 4.3 1.6e-12 47.4 4.3 1.6 1 1 0 1 1 1 1 AN1-like Zinc finger Transp_Tc5_C PF04236.15 CRK38489.1 - 0.44 10.9 6.2 0.19 12.1 4.1 1.5 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain ADH_N PF08240.12 CRK38490.1 - 5.8e-27 93.7 1.1 7.7e-27 93.3 1.1 1.2 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Nucleopor_Nup85 PF07575.13 CRK38491.1 - 5.7e-07 28.5 0.0 7.2e-07 28.2 0.0 1.0 1 0 0 1 1 1 1 Nup85 Nucleoporin Nucleopor_Nup85 PF07575.13 CRK38494.1 - 4.1e-24 85.1 0.0 7.6e-11 41.3 0.0 4.8 3 2 0 3 3 3 3 Nup85 Nucleoporin AAA_lid_7 PF17867.1 CRK38494.1 - 0.0063 16.7 1.0 5.6 7.2 0.1 2.7 2 0 0 2 2 2 2 Midasin AAA lid domain DUF952 PF06108.12 CRK38496.1 - 2.1e-21 75.7 0.0 2.7e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF952) UCH PF00443.29 CRK38497.1 - 1.6e-15 57.4 0.0 2.3e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CRK38497.1 - 0.017 14.7 0.1 0.028 14.0 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase SAE2 PF08573.10 CRK38498.1 - 2e-34 119.1 3.2 4e-34 118.1 0.1 2.8 2 0 0 2 2 2 1 DNA repair protein endonuclease SAE2/CtIP C-terminus HrpB7 PF09486.10 CRK38498.1 - 7.8e-05 23.1 2.3 7.8e-05 23.1 2.3 3.1 3 0 0 3 3 3 1 Bacterial type III secretion protein (HrpB7) ABC_tran_CTD PF16326.5 CRK38498.1 - 0.015 15.5 0.5 0.015 15.5 0.5 3.3 3 2 0 3 3 3 0 ABC transporter C-terminal domain Bacillus_HBL PF05791.11 CRK38498.1 - 0.1 12.4 1.7 0.72 9.7 0.3 2.3 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) AAA_13 PF13166.6 CRK38498.1 - 0.22 10.1 0.9 0.42 9.2 0.9 1.4 1 0 0 1 1 1 0 AAA domain CLZ PF16526.5 CRK38498.1 - 0.24 11.8 10.7 0.042 14.2 1.8 3.3 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels SOGA PF11365.8 CRK38498.1 - 0.26 12.4 4.2 1.4 10.0 0.4 2.9 1 1 1 2 2 2 0 Protein SOGA HemX PF04375.14 CRK38498.1 - 0.26 10.5 6.2 0.031 13.6 1.1 1.9 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Laminin_I PF06008.14 CRK38498.1 - 0.34 10.6 7.0 0.28 10.9 1.2 2.6 2 0 0 2 2 2 0 Laminin Domain I LPP PF04728.13 CRK38498.1 - 0.54 10.7 2.6 39 4.7 0.1 3.6 4 0 0 4 4 4 0 Lipoprotein leucine-zipper BLOC1_2 PF10046.9 CRK38498.1 - 1.3 9.4 3.5 0.99 9.8 0.5 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc7 PF08317.11 CRK38498.1 - 4.7 6.0 7.0 1.6 7.5 0.9 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein zf-CCHC PF00098.23 CRK38499.1 - 3.2e-47 156.6 53.0 4.7e-09 35.9 3.1 6.2 6 0 0 6 6 6 6 Zinc knuckle zf-CCHC_4 PF14392.6 CRK38499.1 - 2.3e-13 49.6 31.7 0.00014 21.5 0.3 6.1 6 0 0 6 6 6 6 Zinc knuckle zf-CCHC_3 PF13917.6 CRK38499.1 - 4.3e-11 42.6 33.2 0.022 14.7 0.9 6.0 3 2 3 6 6 6 5 Zinc knuckle zf-CCHC_6 PF15288.6 CRK38499.1 - 1.5e-08 34.3 42.7 0.0071 16.2 0.7 6.3 5 1 1 6 6 6 5 Zinc knuckle zf-CCHC_2 PF13696.6 CRK38499.1 - 0.068 13.0 3.9 0.068 13.0 3.9 6.2 6 0 0 6 6 6 0 Zinc knuckle Keratin_2_head PF16208.5 CRK38499.1 - 0.49 10.5 26.7 0.67 10.1 26.7 1.3 1 0 0 1 1 1 0 Keratin type II head zf-CCHC_5 PF14787.6 CRK38499.1 - 0.57 9.9 35.0 0.64 9.8 1.6 5.6 4 2 2 6 6 6 0 GAG-polyprotein viral zinc-finger Acyl-CoA_dh_1 PF00441.24 CRK38500.1 - 1.5e-26 93.4 0.2 2e-26 93.0 0.2 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 CRK38500.1 - 1.2e-08 35.0 0.0 2.1e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_2 PF08028.11 CRK38500.1 - 5.6e-05 23.4 0.0 9.6e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Amino_oxidase PF01593.24 CRK38501.1 - 8.6e-49 167.0 0.0 1.7e-48 166.1 0.0 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CRK38501.1 - 2.9e-16 59.4 0.1 6e-16 58.4 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CRK38501.1 - 7.1e-07 28.7 0.1 9.8e-06 25.0 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CRK38501.1 - 9.3e-07 28.3 0.5 0.00011 21.4 0.7 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 CRK38501.1 - 1.1e-05 25.8 0.1 2.6e-05 24.7 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CRK38501.1 - 1.2e-05 25.4 0.0 0.0042 17.1 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.24 CRK38501.1 - 1.5e-05 24.8 2.9 4.7e-05 23.1 1.1 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 CRK38501.1 - 4.1e-05 22.5 0.2 0.00029 19.7 0.1 1.9 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 CRK38501.1 - 0.00034 20.0 0.6 0.00049 19.4 0.6 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 CRK38501.1 - 0.0025 17.2 1.0 0.0074 15.7 1.0 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase 3HCDH_N PF02737.18 CRK38501.1 - 0.0035 17.2 0.1 0.0055 16.6 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 CRK38501.1 - 0.0044 16.2 0.1 0.0064 15.6 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.17 CRK38501.1 - 0.024 13.9 0.0 0.04 13.2 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 CRK38501.1 - 0.035 13.1 0.2 0.054 12.5 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 CRK38501.1 - 0.054 12.8 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ATG2_CAD PF13329.6 CRK38502.1 - 2.7e-50 170.1 0.6 7.9e-50 168.6 0.4 2.0 2 0 0 2 2 2 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.11 CRK38502.1 - 1.1e-30 105.8 0.1 7.2e-29 100.0 0.0 3.6 4 0 0 4 4 4 1 Autophagy-related protein C terminal domain Chorein_N PF12624.7 CRK38502.1 - 3.3e-06 27.2 0.0 1.6e-05 25.0 0.0 2.1 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 DHDPS PF00701.22 CRK38503.1 - 3.5e-26 91.6 0.0 4.9e-26 91.1 0.0 1.2 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family ThiF PF00899.21 CRK38505.1 - 1.6e-24 86.6 0.1 1.9e-24 86.4 0.1 1.1 1 0 0 1 1 1 1 ThiF family Ubiq_cyt_C_chap PF03981.12 CRK38506.1 - 3e-21 76.0 0.5 2.6e-20 73.0 0.6 1.9 2 0 0 2 2 2 1 Ubiquinol-cytochrome C chaperone DUF508 PF04370.12 CRK38506.1 - 0.11 12.3 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF508) IPK PF03770.16 CRK38508.1 - 0.00014 21.8 0.0 0.00015 21.7 0.0 1.0 1 0 0 1 1 1 1 Inositol polyphosphate kinase Pro-rich_19 PF15455.6 CRK38508.1 - 0.15 11.2 0.1 0.17 11.0 0.1 1.1 1 0 0 1 1 1 0 Proline-rich 19 FMN_dh PF01070.18 CRK38513.1 - 8.3e-41 140.2 0.2 9.3e-41 140.0 0.2 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 CRK38513.1 - 5.3e-05 22.5 0.1 6.8e-05 22.2 0.1 1.1 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 CRK38513.1 - 0.00031 20.2 0.0 0.00032 20.2 0.0 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 CRK38513.1 - 0.00034 19.7 0.0 0.00043 19.4 0.0 1.2 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Bgal_small_N PF02929.17 CRK38516.1 - 8.3e-17 61.6 0.0 8.8e-17 61.5 0.0 1.0 1 0 0 1 1 1 1 Beta galactosidase small chain Oxysterol_BP PF01237.18 CRK38518.1 - 2.8e-11 42.9 0.0 3e-11 42.8 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein DNA_ligase_A_N PF04675.14 CRK38541.1 - 6.9e-14 52.5 0.0 7.6e-14 52.4 0.0 1.0 1 0 0 1 1 1 1 DNA ligase N terminus Syntaxin PF00804.25 CRK38545.1 - 1.6e-25 89.9 16.1 1.6e-25 89.9 16.1 1.5 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.19 CRK38545.1 - 8.9e-12 44.8 3.0 8.9e-12 44.8 3.0 2.1 2 0 0 2 2 1 1 SNARE domain DUF2951 PF11166.8 CRK38545.1 - 0.048 13.9 0.2 0.048 13.9 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) DUF3094 PF11293.8 CRK38545.1 - 0.059 13.1 0.1 0.15 11.8 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3094) DUF2207 PF09972.9 CRK38545.1 - 0.15 10.8 2.6 0.14 10.9 0.1 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) PBP1_TM PF14812.6 CRK38545.1 - 0.28 11.6 0.1 0.28 11.6 0.1 2.5 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Allexi_40kDa PF05549.11 CRK38545.1 - 0.59 9.6 14.1 0.21 11.0 6.6 2.2 2 0 0 2 2 2 0 Allexivirus 40kDa protein SKA2 PF16740.5 CRK38545.1 - 1.4 8.7 17.1 0.27 11.0 3.4 3.0 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 2 Prominin PF05478.11 CRK38545.1 - 1.8 6.4 15.9 0.12 10.3 0.4 2.1 1 1 0 2 2 2 0 Prominin Muted PF14942.6 CRK38545.1 - 2.2 8.6 23.1 0.077 13.3 9.6 2.6 2 1 0 2 2 2 0 Organelle biogenesis, Muted-like protein DUF1192 PF06698.11 CRK38545.1 - 2.7 8.1 8.2 14 5.9 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) DUF4094 PF13334.6 CRK38545.1 - 2.7 8.5 9.8 1.1e+03 0.1 8.8 3.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4094) JIP_LZII PF16471.5 CRK38545.1 - 3.9 7.7 14.1 1.9 8.7 0.1 3.8 2 1 2 4 4 4 0 JNK-interacting protein leucine zipper II V-SNARE PF05008.15 CRK38545.1 - 6.1 7.3 17.2 1.2 9.6 1.1 3.3 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus TPR_1 PF00515.28 CRK38546.1 - 9.9e-47 154.9 26.0 3.3e-06 26.7 0.0 11.4 11 1 0 11 11 11 10 Tetratricopeptide repeat TPR_2 PF07719.17 CRK38546.1 - 9.2e-44 144.1 22.0 0.0001 22.1 0.0 11.3 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_16 PF13432.6 CRK38546.1 - 6.3e-27 94.0 5.8 1.9e-06 28.4 0.4 7.7 6 1 2 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.6 CRK38546.1 - 3.9e-26 89.0 22.9 0.0045 17.1 0.0 10.7 11 0 0 11 11 10 6 Tetratricopeptide repeat TPR_17 PF13431.6 CRK38546.1 - 1.7e-25 87.5 6.8 0.00013 22.1 0.0 9.4 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_11 PF13414.6 CRK38546.1 - 5.9e-25 86.7 21.4 1.9e-05 24.2 0.0 8.8 6 2 3 9 9 9 5 TPR repeat TPR_12 PF13424.6 CRK38546.1 - 4.8e-22 78.0 26.0 0.00045 20.5 0.8 9.0 4 3 4 8 8 8 6 Tetratricopeptide repeat TPR_19 PF14559.6 CRK38546.1 - 6.6e-17 61.8 15.4 6.8e-06 26.5 1.7 6.3 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 CRK38546.1 - 3.9e-16 59.0 8.1 1.8e-07 31.2 0.1 5.4 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 CRK38546.1 - 9.2e-15 54.1 15.7 0.0042 17.8 0.4 9.1 4 3 7 11 11 10 3 Tetratricopeptide repeat TPR_7 PF13176.6 CRK38546.1 - 1.3e-11 43.6 16.6 0.033 14.2 0.2 8.8 9 1 1 10 10 8 2 Tetratricopeptide repeat TPR_10 PF13374.6 CRK38546.1 - 1.2e-09 37.7 12.8 0.026 14.4 0.4 8.6 9 0 0 9 9 8 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CRK38546.1 - 1.5e-08 34.7 13.9 5.1e-05 23.4 0.6 5.8 2 2 5 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 CRK38546.1 - 2.7e-08 33.6 2.4 1.4e-07 31.2 2.4 2.1 1 1 0 1 1 1 1 MalT-like TPR region SHNi-TPR PF10516.9 CRK38546.1 - 5.9e-06 25.6 8.2 0.12 11.9 0.0 5.4 6 0 0 6 6 6 2 SHNi-TPR TPR_15 PF13429.6 CRK38546.1 - 0.00011 21.6 5.4 0.89 8.7 0.0 4.7 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 CRK38546.1 - 0.00057 20.4 22.2 13 6.7 0.7 8.9 10 0 0 10 10 7 0 Tetratricopeptide repeat TAF1_subA PF14929.6 CRK38546.1 - 0.00082 18.9 1.1 0.014 14.9 0.3 2.3 1 1 1 2 2 2 1 TAF RNA Polymerase I subunit A MAS20 PF02064.15 CRK38546.1 - 0.0087 16.2 7.1 0.61 10.2 0.9 4.1 4 1 0 4 4 4 1 MAS20 protein import receptor HrpB1_HrpK PF09613.10 CRK38546.1 - 0.0094 15.6 0.5 0.097 12.3 0.5 2.3 1 1 1 2 2 2 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_4 PF07721.14 CRK38546.1 - 0.02 15.5 0.1 41 5.2 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3856 PF12968.7 CRK38546.1 - 0.03 14.4 6.3 6.8 6.8 0.0 5.7 6 2 0 7 7 6 0 Domain of Unknown Function (DUF3856) FAT PF02259.23 CRK38546.1 - 0.045 13.0 0.4 15 4.6 0.5 3.3 1 1 1 3 3 3 0 FAT domain SPO22 PF08631.10 CRK38546.1 - 0.11 12.0 2.2 9.1 5.7 0.0 3.5 3 1 2 5 5 5 0 Meiosis protein SPO22/ZIP4 like NARP1 PF12569.8 CRK38546.1 - 0.5 9.2 26.4 0.081 11.8 0.4 5.0 2 2 2 4 4 4 0 NMDA receptor-regulated protein 1 MIT PF04212.18 CRK38546.1 - 0.75 9.9 17.3 13 5.9 0.1 6.4 7 0 0 7 7 6 0 MIT (microtubule interacting and transport) domain PPR PF01535.20 CRK38546.1 - 1.2 9.5 3.0 21 5.7 0.0 4.2 4 0 0 4 4 3 0 PPR repeat TPR_20 PF14561.6 CRK38546.1 - 2 8.8 11.9 0.23 11.8 0.3 4.3 5 2 0 5 5 4 0 Tetratricopeptide repeat Sel1 PF08238.12 CRK38546.1 - 2.3 9.0 7.2 1.8 9.4 0.1 4.4 5 0 0 5 5 3 0 Sel1 repeat Usp PF00582.26 CRK38546.1 - 3.9 8.0 5.8 34 4.9 0.1 3.2 3 0 0 3 3 3 0 Universal stress protein family Aminotran_4 PF01063.19 CRK38547.1 - 2.2e-15 57.1 0.0 3.1e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Btz PF09405.10 CRK38548.1 - 9.3e-29 100.3 1.1 2.3e-28 99.1 1.1 1.6 1 0 0 1 1 1 1 CASC3/Barentsz eIF4AIII binding Glyco_hydro_43 PF04616.14 CRK38553.1 - 1.5e-12 47.4 1.8 1.6e-12 47.3 1.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 SHR3_chaperone PF08229.11 CRK38556.1 - 2.6e-59 199.4 0.3 2.8e-59 199.2 0.3 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 DUF5453 PF17534.2 CRK38556.1 - 0.046 13.7 0.7 0.046 13.7 0.7 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5453) Cpn60_TCP1 PF00118.24 CRK38574.1 - 3e-43 148.2 0.4 6.1e-43 147.2 0.4 1.4 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Methyltr_RsmF_N PF17125.5 CRK38574.1 - 0.18 12.3 0.0 0.5 10.9 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain of 16S rRNA methyltransferase RsmF Glyco_hydro_28 PF00295.17 CRK38581.1 - 1.9e-114 382.1 21.3 2.2e-114 381.9 21.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 CBM-like PF14683.6 CRK38581.1 - 0.097 12.5 0.5 0.28 11.1 0.1 1.9 2 0 0 2 2 2 0 Polysaccharide lyase family 4, domain III Arg_repressor_C PF02863.18 CRK38581.1 - 0.13 12.1 1.1 10 6.0 0.1 2.5 2 0 0 2 2 2 0 Arginine repressor, C-terminal domain YajC PF02699.15 CRK38581.1 - 0.84 9.6 2.3 4.2 7.3 0.5 2.8 3 0 0 3 3 3 0 Preprotein translocase subunit adh_short PF00106.25 CRK38584.1 - 9.3e-22 77.4 0.0 8.5e-20 71.0 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK38584.1 - 4.1e-14 52.7 0.0 9.1e-13 48.3 0.0 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK38584.1 - 0.0047 16.9 0.0 0.006 16.5 0.0 1.2 1 0 0 1 1 1 1 KR domain ChlamPMP_M PF07548.11 CRK38584.1 - 0.073 13.0 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Chlamydia polymorphic membrane protein middle domain Polysacc_synt_2 PF02719.15 CRK38584.1 - 0.1 11.7 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Flavi_DEAD PF07652.14 CRK38595.1 - 0.0027 17.7 0.0 0.0032 17.5 0.0 1.1 1 0 0 1 1 1 1 Flavivirus DEAD domain DEAD PF00270.29 CRK38595.1 - 0.17 11.7 0.0 0.18 11.6 0.0 1.1 1 0 0 1 1 1 0 DEAD/DEAH box helicase ResIII PF04851.15 CRK38595.1 - 0.17 11.9 0.0 0.17 11.9 0.0 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit RRM_1 PF00076.22 CRK38600.1 - 2.5e-10 40.0 0.0 0.014 15.2 0.0 4.2 3 1 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FUSC PF04632.12 CRK38600.1 - 0.43 9.0 1.4 0.68 8.4 1.4 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family G-alpha PF00503.20 CRK38602.1 - 6.8e-29 101.1 1.6 7.4e-29 101.0 1.6 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CRK38602.1 - 0.032 13.7 0.1 0.061 12.8 0.1 1.5 1 1 0 1 1 1 0 ADP-ribosylation factor family ADH_N PF08240.12 CRK38609.1 - 1.6e-24 85.9 1.6 3.6e-24 84.7 1.6 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.6 CRK38609.1 - 5.8e-05 22.9 0.1 5.8e-05 22.9 0.1 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated Fungal_trans PF04082.18 CRK38613.1 - 4.9e-47 160.2 0.1 2.5e-24 85.7 0.1 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK38613.1 - 8e-14 51.5 22.3 7.7e-07 29.1 4.9 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Condensin2nSMC PF12422.8 CRK38613.1 - 0.0038 17.4 0.2 3.6 7.8 0.0 3.4 3 0 0 3 3 3 1 Condensin II non structural maintenance of chromosomes subunit DUF2226 PF09987.9 CRK38613.1 - 0.014 14.8 0.0 0.81 9.0 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2226) DMT_6 PF04342.12 CRK38613.1 - 0.014 15.6 0.7 7.4 6.8 0.1 2.7 2 0 0 2 2 2 0 Putative member of DMT superfamily (DUF486) DUF1465 PF07323.12 CRK38613.1 - 0.11 12.4 3.9 1.8 8.4 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1465) Nsp1_C PF05064.13 CRK38613.1 - 3.5 7.5 5.7 21 4.9 0.1 3.0 3 0 0 3 3 3 0 Nsp1-like C-terminal region SKG6 PF08693.10 CRK38615.1 - 0.0011 18.3 0.1 0.0011 18.3 0.1 2.1 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Chorion_2 PF03964.15 CRK38615.1 - 0.0013 19.5 1.8 0.0013 19.5 1.8 2.1 2 0 0 2 2 2 1 Chorion family 2 DUF3316 PF11777.8 CRK38615.1 - 0.039 14.0 0.8 0.088 12.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3316) DUF4718 PF15842.5 CRK38615.1 - 0.1 12.4 2.5 11 5.7 3.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4718) PepSY_2 PF13670.6 CRK38615.1 - 0.21 11.6 3.8 3.9 7.5 0.0 2.9 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain KASH PF10541.9 CRK38615.1 - 0.32 11.3 0.1 0.32 11.3 0.1 2.0 2 0 0 2 2 2 0 Nuclear envelope localisation domain TrbC PF04956.13 CRK38615.1 - 0.92 9.8 0.0 0.92 9.8 0.0 2.3 3 0 0 3 3 3 0 TrbC/VIRB2 family SR-25 PF10500.9 CRK38615.1 - 2 8.0 9.1 3.5 7.2 9.1 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein BES1_N PF05687.13 CRK38615.1 - 4.2 7.7 9.2 15 5.9 0.5 2.2 2 0 0 2 2 2 0 BES1/BZR1 plant transcription factor, N-terminal TPR_14 PF13428.6 CRK38625.1 - 1.2e-30 103.6 36.1 1.4e-05 25.5 0.5 13.4 3 2 12 15 15 15 8 Tetratricopeptide repeat TPR_19 PF14559.6 CRK38625.1 - 3.6e-24 85.1 19.6 6.3e-07 29.8 0.9 9.8 5 3 5 11 11 11 5 Tetratricopeptide repeat TPR_2 PF07719.17 CRK38625.1 - 2.8e-12 45.7 15.5 0.13 12.4 0.0 9.5 10 0 0 10 10 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 CRK38625.1 - 3e-12 47.0 29.5 0.00071 20.2 1.4 7.6 7 1 1 8 8 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 CRK38625.1 - 4.2e-11 42.1 3.4 0.022 14.9 0.0 7.8 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 CRK38625.1 - 1.6e-10 40.6 6.5 1.2 9.7 0.1 9.5 7 3 2 9 9 9 1 Tetratricopeptide repeat TPR_15 PF13429.6 CRK38625.1 - 9.3e-10 38.2 26.8 0.00082 18.7 5.1 6.9 2 2 4 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 CRK38625.1 - 1.9e-06 27.4 3.0 0.21 11.5 0.1 5.1 6 0 0 6 6 6 2 Tetratricopeptide repeat NARP1 PF12569.8 CRK38625.1 - 2.3e-06 26.8 0.4 0.76 8.6 0.0 4.6 2 1 3 5 5 5 2 NMDA receptor-regulated protein 1 TPR_21 PF09976.9 CRK38625.1 - 5.3e-06 26.3 6.6 0.016 14.9 1.5 3.5 1 1 2 3 3 3 2 Tetratricopeptide repeat-like domain TPR_6 PF13174.6 CRK38625.1 - 1e-05 25.8 8.7 35 5.3 0.1 8.8 11 0 0 11 11 9 0 Tetratricopeptide repeat TPR_11 PF13414.6 CRK38625.1 - 1.9e-05 24.2 10.2 2.1 8.1 0.1 7.1 8 1 1 9 9 9 2 TPR repeat TPR_9 PF13371.6 CRK38625.1 - 2.8e-05 24.2 11.8 0.015 15.4 0.1 6.4 5 1 1 6 6 6 1 Tetratricopeptide repeat Wzy_C_2 PF11846.8 CRK38625.1 - 9e-05 22.5 3.0 0.59 10.0 0.2 3.9 3 1 1 4 4 4 2 Virulence factor membrane-bound polymerase, C-terminal ANAPC3 PF12895.7 CRK38625.1 - 0.0012 19.0 2.2 6.7 7.0 0.1 4.7 3 1 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 ZNRF_3_ecto PF18212.1 CRK38625.1 - 0.0079 16.2 1.5 6.6 6.8 0.0 4.7 4 1 1 5 5 5 1 ZNRF-3 Ectodomain DUF3808 PF10300.9 CRK38625.1 - 0.017 13.9 0.8 5.4 5.6 0.0 4.1 6 0 0 6 6 6 0 Protein of unknown function (DUF3808) Suf PF05843.14 CRK38625.1 - 0.019 15.0 0.0 14 5.6 0.0 3.7 3 1 1 4 4 4 0 Suppressor of forked protein (Suf) TPR_12 PF13424.6 CRK38625.1 - 0.77 10.1 11.9 21 5.5 0.3 6.4 8 2 0 8 8 6 0 Tetratricopeptide repeat ChAPs PF09295.10 CRK38625.1 - 0.9 8.5 6.4 7 5.5 0.1 3.3 2 1 1 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) V-ATPase_G_2 PF16999.5 CRK38626.1 - 0.13 12.6 7.4 0.085 13.3 2.5 2.1 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit YdfA_immunity PF12127.8 CRK38626.1 - 6.5 5.7 9.5 0.37 9.8 4.3 1.5 2 0 0 2 2 2 0 SigmaW regulon antibacterial ATP-synt_B PF00430.18 CRK38626.1 - 9.4 6.3 15.7 2.6 8.1 11.9 1.8 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) Pex24p PF06398.11 CRK38627.1 - 3.3 6.6 15.5 5.5 5.9 15.5 1.3 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin PPR_2 PF13041.6 CRK38628.1 - 4.8e-05 23.5 0.0 0.19 11.9 0.0 2.7 2 0 0 2 2 2 2 PPR repeat family PPR_3 PF13812.6 CRK38628.1 - 0.021 14.9 0.0 0.053 13.6 0.0 1.7 1 0 0 1 1 1 0 Pentatricopeptide repeat domain PP2C PF00481.21 CRK38629.1 - 3.4e-07 30.2 0.1 0.0011 18.7 0.0 2.2 1 1 1 2 2 2 2 Protein phosphatase 2C ERAP1_C PF11838.8 CRK38635.1 - 1.2e-19 71.0 0.0 1.3e-19 70.9 0.0 1.0 1 0 0 1 1 1 1 ERAP1-like C-terminal domain MSL2-CXC PF16682.5 CRK38638.1 - 0.0022 18.1 3.2 0.0039 17.3 3.2 1.4 1 0 0 1 1 1 1 CXC domain of E3 ubiquitin-protein ligase MSL2 Velvet PF11754.8 CRK38639.1 - 1.5e-48 165.9 0.1 3.4e-30 105.8 0.0 3.5 2 2 1 3 3 3 2 Velvet factor Spt20 PF12090.8 CRK38641.1 - 0.066 12.8 14.3 0.29 10.7 2.6 2.3 2 0 0 2 2 2 0 Spt20 family Secretin_N_2 PF07655.13 CRK38641.1 - 0.12 12.9 0.1 0.12 12.9 0.1 4.2 4 1 0 4 4 4 0 Secretin N-terminal domain PGA2 PF07543.12 CRK38641.1 - 1 9.3 5.4 0.69 9.9 1.1 2.4 2 0 0 2 2 2 0 Protein trafficking PGA2 Ank_4 PF13637.6 CRK38642.1 - 3.9e-09 36.9 0.1 2.8e-06 27.7 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 CRK38642.1 - 2.4e-08 34.1 0.0 5.4e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) TIG PF01833.24 CRK38642.1 - 3.1e-08 33.6 0.2 7.1e-08 32.4 0.2 1.6 1 0 0 1 1 1 1 IPT/TIG domain Ank_2 PF12796.7 CRK38642.1 - 1.3e-07 32.0 0.0 3.5e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 CRK38642.1 - 9.5e-06 25.8 0.0 0.0011 19.3 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 CRK38642.1 - 0.0002 21.5 0.1 0.0038 17.6 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat PIG-S PF10510.9 CRK38646.1 - 1.3e-38 133.2 0.0 1.5e-38 132.9 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Patatin PF01734.22 CRK38647.1 - 0.00078 19.7 0.6 0.003 17.7 0.2 2.0 2 0 0 2 2 2 1 Patatin-like phospholipase Hydrolase_4 PF12146.8 CRK38647.1 - 0.12 11.7 0.1 0.2 10.9 0.1 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 AMP-binding PF00501.28 CRK38649.1 - 2.9e-81 273.2 0.2 1.2e-67 228.4 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 CRK38649.1 - 1.3e-10 42.1 0.1 3.5e-10 40.7 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Bep_C_terminal PF17841.1 CRK38649.1 - 0.029 14.6 0.0 15 5.9 0.0 2.5 2 0 0 2 2 2 0 BID domain of Bartonella effector protein (Bep) Aldo_ket_red PF00248.21 CRK38650.1 - 6.1e-71 239.0 0.0 6.9e-71 238.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Fig1 PF12351.8 CRK38651.1 - 1.3e-09 38.3 0.0 1.3e-09 38.3 0.0 1.4 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 TetR_C_35 PF18556.1 CRK38651.1 - 0.046 13.9 0.0 0.087 13.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial Tetracyclin repressor, C-terminal domain Ank_2 PF12796.7 CRK38652.1 - 5.2e-42 142.3 4.8 8.7e-13 48.7 0.0 3.8 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CRK38652.1 - 2.1e-30 104.7 8.7 6.1e-08 33.1 0.0 5.5 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 CRK38652.1 - 8.4e-27 90.3 3.6 0.00017 21.8 0.0 7.1 7 0 0 7 7 6 6 Ankyrin repeat Ank_5 PF13857.6 CRK38652.1 - 2.1e-18 66.1 5.5 0.0026 18.0 0.1 6.3 1 1 5 6 6 6 6 Ankyrin repeats (many copies) CorA PF01544.18 CRK38652.1 - 1.7e-17 63.7 9.3 7.7e-09 35.3 1.6 2.7 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein Ank PF00023.30 CRK38652.1 - 4.5e-17 61.7 5.7 0.00028 21.2 0.0 7.0 7 0 0 7 7 7 5 Ankyrin repeat Yip1 PF04893.17 CRK38652.1 - 8.9e-05 22.3 28.3 0.012 15.3 10.1 2.3 2 0 0 2 2 2 2 Yip1 domain CD225 PF04505.12 CRK38652.1 - 0.00026 21.1 0.3 1.7 8.8 0.0 3.1 2 0 0 2 2 2 2 Interferon-induced transmembrane protein IL31 PF15209.6 CRK38652.1 - 0.00064 19.5 5.0 0.34 10.7 0.4 2.4 2 0 0 2 2 2 2 Interleukin 31 Wbp11 PF09429.10 CRK38652.1 - 0.0034 17.7 13.4 0.28 11.6 2.9 2.6 2 0 0 2 2 2 2 WW domain binding protein 11 DUF1622 PF07784.11 CRK38652.1 - 0.033 14.1 1.8 8.1 6.4 0.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1622) NiFe-hyd_HybE PF11939.8 CRK38652.1 - 0.1 12.5 4.2 5.9 6.8 0.4 2.5 2 0 0 2 2 2 0 [NiFe]-hydrogenase assembly, chaperone, HybE HTH_30 PF13556.6 CRK38652.1 - 0.13 12.0 2.2 37 4.2 0.1 3.7 3 0 0 3 3 3 0 PucR C-terminal helix-turn-helix domain FAD-oxidase_C PF02913.19 CRK38652.1 - 0.27 10.8 4.2 6.8 6.2 0.3 2.3 2 0 0 2 2 2 0 FAD linked oxidases, C-terminal domain V_ATPase_I PF01496.19 CRK38652.1 - 1.5 6.7 9.0 2.6 5.8 1.2 2.2 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF2590 PF10761.9 CRK38652.1 - 1.7 8.8 4.2 13 6.0 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2590) PRKG1_interact PF15898.5 CRK38652.1 - 2.6 9.0 19.2 9.6 7.2 6.2 2.8 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF5315 PF17242.2 CRK38652.1 - 3.7 7.4 10.2 11 5.9 0.5 3.2 2 1 0 3 3 3 0 Disordered region of unknown function (DUF5315) MCU PF04678.13 CRK38652.1 - 5 7.2 13.1 11 6.1 4.1 2.5 2 0 0 2 2 2 0 Mitochondrial calcium uniporter GFO_IDH_MocA PF01408.22 CRK38653.1 - 4.5e-16 59.8 0.4 7.8e-16 59.0 0.4 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold AMP-binding PF00501.28 CRK38653.1 - 1.8e-13 49.9 1.0 6.3e-13 48.1 0.1 2.0 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.6 CRK38653.1 - 1.3e-10 42.1 0.0 3.9e-10 40.6 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AhpC-TSA PF00578.21 CRK38653.1 - 0.016 15.1 0.1 0.096 12.6 0.0 2.1 2 0 0 2 2 2 0 AhpC/TSA family DXP_reductoisom PF02670.16 CRK38653.1 - 0.18 12.5 0.1 0.57 10.9 0.0 1.8 1 1 1 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Aldo_ket_red PF00248.21 CRK38654.1 - 0.00064 19.0 0.1 0.00074 18.8 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Fig1 PF12351.8 CRK38655.1 - 6.1e-41 140.4 4.9 6.1e-41 140.4 4.9 1.7 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 Spo7 PF03907.13 CRK38655.1 - 0.038 13.5 0.0 0.079 12.4 0.0 1.5 1 0 0 1 1 1 0 Spo7-like protein TetR_C_35 PF18556.1 CRK38655.1 - 0.14 12.3 0.1 0.31 11.2 0.1 1.5 1 0 0 1 1 1 0 Bacterial Tetracyclin repressor, C-terminal domain E1-E2_ATPase PF00122.20 CRK38655.1 - 0.25 10.8 0.1 0.25 10.8 0.1 2.7 2 1 1 4 4 4 0 E1-E2 ATPase Ank_4 PF13637.6 CRK38656.1 - 2.9e-36 123.4 8.2 3.5e-09 37.0 0.0 5.7 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 CRK38656.1 - 6e-35 119.7 2.5 2.7e-12 47.1 0.0 3.9 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CRK38656.1 - 2.8e-30 101.0 2.3 8.5e-06 25.8 0.0 7.1 7 0 0 7 7 7 6 Ankyrin repeat Ank PF00023.30 CRK38656.1 - 9.6e-21 73.3 5.7 3.9e-06 27.1 0.1 7.1 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 CRK38656.1 - 2.3e-20 72.4 5.0 0.0023 18.2 0.1 6.3 1 1 5 6 6 6 6 Ankyrin repeats (many copies) AhpC-TSA PF00578.21 CRK38657.1 - 4.1e-29 101.0 0.0 8e-29 100.1 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CRK38657.1 - 5.5e-13 48.9 0.0 1.5e-12 47.4 0.0 1.7 2 0 0 2 2 2 1 Redoxin 1-cysPrx_C PF10417.9 CRK38657.1 - 1.5e-11 44.0 0.2 3.9e-11 42.6 0.2 1.8 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin GFO_IDH_MocA PF01408.22 CRK38657.1 - 9.3e-08 32.9 2.3 5e-07 30.6 1.7 2.2 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 CRK38657.1 - 0.065 13.8 0.1 0.22 12.2 0.1 1.9 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Thioredoxin_8 PF13905.6 CRK38657.1 - 0.12 12.7 0.0 4.7 7.6 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin-like Kelch_4 PF13418.6 CRK38659.1 - 5.5e-16 58.3 0.2 1.6e-05 24.8 0.0 4.7 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_3 PF13415.6 CRK38659.1 - 6.9e-14 51.7 4.4 7e-08 32.6 0.0 5.4 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.25 CRK38659.1 - 2.6e-12 46.1 0.1 0.0027 17.3 0.0 4.6 4 0 0 4 4 4 3 Kelch motif Kelch_5 PF13854.6 CRK38659.1 - 2.2e-11 43.5 6.2 3.2e-05 23.8 0.1 4.1 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 CRK38659.1 - 2.2e-11 43.6 4.0 0.0074 16.5 0.9 4.7 3 1 1 4 4 4 3 Kelch motif Kelch_2 PF07646.15 CRK38659.1 - 3.9e-07 29.8 0.3 0.0018 18.2 0.0 4.4 5 1 0 5 5 5 1 Kelch motif BTB PF00651.31 CRK38659.1 - 0.012 15.8 0.0 0.38 11.0 0.0 2.4 2 0 0 2 2 2 0 BTB/POZ domain DUF2236 PF09995.9 CRK38661.1 - 1.8e-10 41.4 0.3 2.7e-10 40.8 0.3 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Myb_DNA-binding PF00249.31 CRK38662.1 - 1.9e-07 31.2 0.2 1.6e-06 28.2 0.0 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CRK38662.1 - 5.3e-05 23.4 0.1 0.00019 21.6 0.0 1.9 1 1 1 2 2 2 1 Myb-like DNA-binding domain Rap1_C PF11626.8 CRK38662.1 - 0.02 15.0 0.0 0.04 14.0 0.0 1.5 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain UbiA PF01040.18 CRK38663.1 - 6e-39 133.9 18.9 6e-39 133.9 18.9 1.9 1 1 0 1 1 1 1 UbiA prenyltransferase family SMYLE_N PF18615.1 CRK38663.1 - 0.42 10.1 7.5 0.59 9.6 7.5 1.1 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Med3 PF11593.8 CRK38663.1 - 2.8 7.0 15.5 4.1 6.5 15.5 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal KIF1B PF12423.8 CRK38664.1 - 0.15 12.5 0.1 0.74 10.3 0.1 2.2 1 0 0 1 1 1 0 Kinesin protein 1B zf-Di19 PF05605.12 CRK38664.1 - 0.44 10.9 18.3 0.16 12.3 2.1 4.2 4 0 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding Mut7-C PF01927.16 CRK38664.1 - 0.7 10.0 2.6 8.6 6.5 1.2 2.7 2 0 0 2 2 2 0 Mut7-C RNAse domain zf-C2H2_3 PF13878.6 CRK38664.1 - 1.9 8.4 11.6 1.8 8.4 0.3 4.6 4 0 0 4 4 4 0 zinc-finger of acetyl-transferase ESCO Oxidored_molyb PF00174.19 CRK38665.1 - 2.4e-56 190.0 0.0 3.3e-56 189.6 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 CRK38665.1 - 9.5e-27 93.7 0.3 9.5e-27 93.7 0.3 2.4 3 1 0 3 3 3 1 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.28 CRK38665.1 - 4.8e-11 42.7 0.0 8.2e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RPN2_C PF18004.1 CRK38667.1 - 3.7e-57 192.7 5.9 3.7e-57 192.7 5.9 1.8 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 CRK38667.1 - 1.5e-42 141.9 21.6 8.6e-09 35.4 0.0 8.7 8 0 0 8 8 8 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 CRK38667.1 - 1.2e-19 70.4 0.0 2.7e-14 53.3 0.0 4.7 3 1 2 5 5 5 2 HEAT repeats HEAT PF02985.22 CRK38667.1 - 5.3e-06 26.2 0.4 2.2 8.7 0.0 5.5 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.6 CRK38667.1 - 1.2e-05 25.6 0.1 0.015 15.8 0.0 4.7 3 1 1 4 4 4 2 HEAT-like repeat Cnd1 PF12717.7 CRK38667.1 - 0.0051 16.9 0.0 2.1 8.4 0.0 2.8 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 mRNA_triPase PF02940.15 CRK38669.1 - 1.9e-51 174.9 0.0 3.4e-51 174.1 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain AA_permease_2 PF13520.6 CRK38673.1 - 3.8e-63 213.8 22.5 7.5e-63 212.8 21.8 1.8 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CRK38673.1 - 3.2e-08 32.6 14.4 3.2e-08 32.6 14.4 3.3 3 1 0 3 3 3 1 Amino acid permease Glyco_hydro_88 PF07470.13 CRK38676.1 - 1.3e-62 211.8 3.2 1.9e-62 211.4 3.2 1.1 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Xan_ur_permease PF00860.20 CRK38678.1 - 1.9e-59 201.3 34.9 1e-57 195.6 34.9 2.1 1 1 0 1 1 1 1 Permease family Glyco_hydro_88 PF07470.13 CRK38681.1 - 2.1e-46 158.6 0.5 2.4e-46 158.4 0.5 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Xan_ur_permease PF00860.20 CRK38683.1 - 5e-59 199.9 35.1 2.9e-57 194.2 35.1 2.1 1 1 0 1 1 1 1 Permease family MARVEL PF01284.23 CRK38684.1 - 1e-18 67.7 24.1 1e-18 67.7 24.1 1.5 2 0 0 2 2 2 1 Membrane-associating domain BUD22 PF09073.10 CRK38684.1 - 0.0016 17.9 4.4 0.0025 17.2 4.4 1.3 1 0 0 1 1 1 1 BUD22 TctB PF07331.11 CRK38684.1 - 0.017 15.4 10.0 0.039 14.2 10.0 1.6 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family Sigma70_ner PF04546.13 CRK38684.1 - 0.45 10.4 3.8 0.76 9.6 3.8 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.14 CRK38684.1 - 4.4 5.5 11.3 6.6 4.9 11.3 1.1 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.13 CRK38684.1 - 6.7 6.7 12.0 12 5.9 12.0 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Glyco_hydro_18 PF00704.28 CRK38687.1 - 2.5e-66 224.6 0.0 2.9e-66 224.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 GDPD PF03009.17 CRK38689.1 - 1.7e-17 64.0 0.0 3.5e-12 46.6 0.0 2.4 2 1 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family MARVEL PF01284.23 CRK38691.1 - 3.3e-20 72.6 23.9 3.9e-20 72.3 23.9 1.1 1 0 0 1 1 1 1 Membrane-associating domain TctB PF07331.11 CRK38691.1 - 0.063 13.6 14.8 0.092 13.0 14.8 1.3 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family DUF2070 PF09843.9 CRK38691.1 - 9.5 4.4 11.4 12 4.0 11.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) HET PF06985.11 CRK38695.1 - 1.4e-06 28.7 0.0 2.1e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MARVEL PF01284.23 CRK38697.1 - 3.5e-05 23.9 18.0 4.8e-05 23.4 18.0 1.2 1 0 0 1 1 1 1 Membrane-associating domain Neur_chan_memb PF02932.16 CRK38697.1 - 0.01 16.0 2.7 0.013 15.5 0.0 2.1 2 1 0 2 2 2 1 Neurotransmitter-gated ion-channel transmembrane region DUF4293 PF14126.6 CRK38697.1 - 0.017 15.4 6.4 0.017 15.4 6.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) SelK_SelG PF10961.8 CRK38697.1 - 0.31 11.7 2.6 0.35 11.5 0.0 2.4 2 0 0 2 2 2 0 Selenoprotein SelK_SelG 7TMR-DISM_7TM PF07695.11 CRK38697.1 - 0.57 10.0 21.8 2.4 8.0 17.0 2.1 2 0 0 2 2 2 0 7TM diverse intracellular signalling DUF1003 PF06210.11 CRK38697.1 - 3 8.0 5.7 7 6.8 5.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) Diphthamide_syn PF01866.17 CRK38698.1 - 2e-83 280.3 0.0 2.5e-83 280.0 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein MFS_1 PF07690.16 CRK38700.1 - 1.2e-33 116.5 76.4 2.1e-26 92.7 41.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK38700.1 - 1.1e-10 41.1 26.4 3.2e-08 32.9 11.9 2.5 2 1 1 3 3 3 2 Sugar (and other) transporter Fungal_trans_2 PF11951.8 CRK38703.1 - 1.2e-11 44.1 0.0 2.4e-08 33.2 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain eIF-4B PF06273.11 CRK38703.1 - 0.016 14.3 0.0 0.016 14.3 0.0 1.7 3 0 0 3 3 3 0 Plant specific eukaryotic initiation factor 4B Pyr_redox_2 PF07992.14 CRK38705.1 - 4.9e-52 177.0 2.6 7.2e-52 176.4 2.6 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 CRK38705.1 - 5.3e-16 58.3 0.0 1.2e-15 57.2 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.27 CRK38705.1 - 1e-11 45.2 4.2 4e-11 43.3 0.5 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.6 CRK38705.1 - 1.9e-06 28.3 0.0 5.2e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Reductase C-terminal Rieske_2 PF13806.6 CRK38705.1 - 8.1e-05 22.5 0.0 0.00058 19.8 0.0 2.4 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain NAD_binding_9 PF13454.6 CRK38705.1 - 0.0013 18.8 4.1 0.075 13.0 0.0 3.2 3 0 0 3 3 3 2 FAD-NAD(P)-binding DUF1188 PF06690.11 CRK38705.1 - 0.069 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) NAD_binding_7 PF13241.6 CRK38705.1 - 0.1 13.1 0.5 3.9 8.0 0.0 2.6 1 1 1 2 2 2 0 Putative NAD(P)-binding Kelch_1 PF01344.25 CRK38705.1 - 1.3 8.7 5.3 4.4 7.0 0.6 3.1 3 0 0 3 3 3 0 Kelch motif HgmA PF04209.13 CRK38707.1 - 4.2e-168 559.4 0.1 4.9e-168 559.2 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase SKG6 PF08693.10 CRK38709.1 - 0.00048 19.5 1.2 0.00048 19.5 1.2 2.2 3 0 0 3 3 3 1 Transmembrane alpha-helix domain Chorion_2 PF03964.15 CRK38709.1 - 0.0033 18.3 3.0 0.0033 18.3 3.0 2.1 2 0 0 2 2 2 1 Chorion family 2 MAP17 PF15807.5 CRK38709.1 - 0.015 15.5 0.0 0.032 14.5 0.0 1.5 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF3316 PF11777.8 CRK38709.1 - 0.017 15.2 0.1 0.068 13.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3316) DUF4718 PF15842.5 CRK38709.1 - 0.036 13.9 2.4 19 5.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4718) GT87 PF09594.10 CRK38709.1 - 0.039 13.7 0.3 0.039 13.7 0.3 1.5 2 0 0 2 2 2 0 Glycosyltransferase family 87 DUF347 PF03988.12 CRK38709.1 - 0.11 12.7 0.1 0.11 12.7 0.1 1.9 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) PepSY_2 PF13670.6 CRK38709.1 - 0.64 10.1 5.4 13 5.8 0.0 2.9 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain CNDH2_M PF16869.5 CRK38709.1 - 2.3 8.9 6.7 0.1 13.3 0.6 1.9 2 1 0 2 2 2 0 PF16858 Pheromone PF08015.11 CRK38709.1 - 4.5 8.4 15.2 0.84 10.7 9.7 2.2 2 0 0 2 2 2 0 Fungal mating-type pheromone Condensin2nSMC PF12422.8 CRK38713.1 - 0.055 13.6 0.0 0.063 13.5 0.0 1.1 1 0 0 1 1 1 0 Condensin II non structural maintenance of chromosomes subunit ADH_N PF08240.12 CRK38717.1 - 4.1e-24 84.6 1.6 8.6e-24 83.5 1.6 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CRK38717.1 - 4.6e-06 26.6 0.1 2e-05 24.6 0.0 2.1 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 CRK38717.1 - 9.3e-05 22.3 0.1 9.3e-05 22.3 0.1 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated Glu_dehyd_C PF16912.5 CRK38717.1 - 0.12 11.8 0.0 0.32 10.4 0.0 1.6 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus ADH_N PF08240.12 CRK38718.1 - 6.9e-24 83.8 1.6 1.7e-23 82.6 1.6 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CRK38718.1 - 6.2e-09 35.9 0.1 3.6e-05 23.8 0.0 2.7 3 0 0 3 3 3 2 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 CRK38718.1 - 0.00014 21.7 0.1 0.00014 21.7 0.1 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated Glu_dehyd_C PF16912.5 CRK38718.1 - 0.0083 15.6 0.0 0.53 9.7 0.0 2.4 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus Tropomyosin PF00261.20 CRK38720.1 - 6.8e-05 22.3 41.4 0.012 15.0 14.0 2.4 2 0 0 2 2 2 2 Tropomyosin FPP PF05911.11 CRK38720.1 - 8.3e-05 21.0 30.8 0.017 13.4 8.1 2.4 2 0 0 2 2 2 2 Filament-like plant protein, long coiled-coil DivIVA PF05103.13 CRK38720.1 - 0.00013 22.1 41.0 0.18 11.9 13.3 5.5 4 2 1 5 5 5 3 DivIVA protein ROS_MUCR PF05443.11 CRK38720.1 - 0.0031 17.6 0.1 5 7.2 0.0 3.2 2 0 0 2 2 2 2 ROS/MUCR transcriptional regulator protein XLF PF09302.11 CRK38720.1 - 0.083 13.0 13.6 0.96 9.6 0.9 3.4 2 2 0 2 2 2 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component DUF5532 PF17673.1 CRK38720.1 - 0.09 12.8 2.4 4.4 7.4 0.2 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5532) FAA_hydro_N_2 PF18288.1 CRK38720.1 - 0.23 11.9 3.3 14 6.2 0.3 3.1 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal domain 2 CHD5 PF04420.14 CRK38720.1 - 0.29 11.0 15.9 1.4 8.8 2.2 2.9 2 1 1 3 3 3 0 CHD5-like protein LST1 PF05083.13 CRK38720.1 - 0.4 11.0 3.5 30 5.0 0.3 3.3 2 0 0 2 2 2 0 LST-1 protein Phage_GP20 PF06810.11 CRK38720.1 - 0.43 10.4 21.0 1.3 8.9 4.4 4.0 2 2 1 3 3 3 0 Phage minor structural protein GP20 HMMR_N PF15905.5 CRK38720.1 - 0.58 9.6 46.4 0.045 13.2 0.4 4.5 4 1 0 4 4 4 0 Hyaluronan mediated motility receptor N-terminal DUF4200 PF13863.6 CRK38720.1 - 0.68 10.3 38.6 2.5 8.5 12.9 4.3 2 2 0 3 3 3 0 Domain of unknown function (DUF4200) Leu_zip PF15294.6 CRK38720.1 - 2.2 7.7 38.9 0.3 10.6 17.3 2.8 2 1 0 2 2 2 0 Leucine zipper LemA PF04011.12 CRK38720.1 - 4.1 7.2 9.4 8.2 6.3 0.3 3.3 2 1 0 2 2 2 0 LemA family Exonuc_VII_L PF02601.15 CRK38720.1 - 5.2 6.5 31.6 3.8 7.0 9.6 2.8 2 1 0 2 2 2 0 Exonuclease VII, large subunit CENP-F_leu_zip PF10473.9 CRK38720.1 - 6.9 6.7 48.3 2.1 8.4 2.4 4.9 2 2 0 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Rft-1 PF04506.13 CRK38722.1 - 4.3e-147 491.0 6.7 5.3e-147 490.6 6.7 1.0 1 0 0 1 1 1 1 Rft protein Polysacc_synt PF01943.17 CRK38722.1 - 8.1e-07 28.7 17.7 8.1e-07 28.7 17.7 2.9 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein Polysacc_synt_3 PF13440.6 CRK38722.1 - 0.0078 15.5 0.2 0.0078 15.5 0.2 2.6 3 0 0 3 3 3 2 Polysaccharide biosynthesis protein Helicase_C PF00271.31 CRK38724.1 - 4e-15 56.1 0.2 8.8e-15 55.0 0.2 1.7 1 1 0 1 1 1 1 Helicase conserved C-terminal domain FPP PF05911.11 CRK38724.1 - 0.0034 15.7 14.7 0.0044 15.3 14.7 1.1 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil DivIVA PF05103.13 CRK38724.1 - 0.0058 16.7 13.2 0.0058 16.7 13.2 1.8 1 1 1 2 2 2 1 DivIVA protein THP2 PF09432.10 CRK38724.1 - 0.0059 16.6 4.1 0.73 9.9 0.2 2.3 2 0 0 2 2 2 2 Tho complex subunit THP2 Fib_alpha PF08702.10 CRK38724.1 - 0.11 12.7 12.6 0.032 14.4 3.9 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF1687 PF07955.11 CRK38724.1 - 0.11 13.0 0.1 7 7.1 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1687) Fez1 PF06818.15 CRK38724.1 - 0.13 12.7 18.2 0.21 12.0 18.2 1.2 1 0 0 1 1 1 0 Fez1 Tropomyosin PF00261.20 CRK38724.1 - 0.42 9.9 27.0 0.062 12.7 14.5 2.5 1 1 1 2 2 2 0 Tropomyosin CENP-F_leu_zip PF10473.9 CRK38724.1 - 0.52 10.3 26.0 0.69 9.9 14.5 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ABC_tran_CTD PF16326.5 CRK38724.1 - 0.66 10.3 21.1 0.94 9.8 2.4 3.3 1 1 2 3 3 3 0 ABC transporter C-terminal domain HALZ PF02183.18 CRK38724.1 - 0.75 10.1 8.1 9.8 6.5 1.7 3.8 2 1 1 3 3 3 0 Homeobox associated leucine zipper Tropomyosin_1 PF12718.7 CRK38724.1 - 0.93 9.6 24.9 0.14 12.3 14.6 2.0 1 1 1 2 2 2 0 Tropomyosin like DUF1664 PF07889.12 CRK38724.1 - 1.2 9.2 7.0 0.43 10.6 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4472 PF14739.6 CRK38724.1 - 1.4 9.7 19.1 2.4 8.9 6.6 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4472) SHE3 PF17078.5 CRK38724.1 - 1.6 8.4 15.9 0.061 13.0 4.1 2.2 1 1 0 2 2 2 0 SWI5-dependent HO expression protein 3 AAA_13 PF13166.6 CRK38724.1 - 1.6 7.2 10.0 2.8 6.5 10.0 1.3 1 0 0 1 1 1 0 AAA domain ADIP PF11559.8 CRK38724.1 - 1.9 8.5 24.0 0.44 10.6 9.4 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding CHD5 PF04420.14 CRK38724.1 - 2 8.3 9.7 0.82 9.5 5.0 2.2 1 1 1 2 2 2 0 CHD5-like protein DHR10 PF18595.1 CRK38724.1 - 2.1 8.4 30.9 0.64 10.1 3.8 2.8 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain CENP-Q PF13094.6 CRK38724.1 - 3.7 7.7 24.6 2.2 8.4 12.9 2.6 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit APG6_N PF17675.1 CRK38724.1 - 4.2 7.9 30.8 0.12 12.9 8.2 2.7 2 1 0 3 3 3 0 Apg6 coiled-coil region TMPIT PF07851.13 CRK38724.1 - 4.9 6.3 13.2 6 6.0 4.5 2.1 1 1 1 2 2 2 0 TMPIT-like protein DUF724 PF05266.14 CRK38724.1 - 5.7 6.7 16.7 2.3 8.0 6.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Jnk-SapK_ap_N PF09744.9 CRK38724.1 - 7.5 6.8 26.4 8.4 6.6 15.4 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 GAS PF13851.6 CRK38724.1 - 9.3 5.5 19.6 92 2.3 19.4 2.1 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding FUSC PF04632.12 CRK38724.1 - 9.4 4.6 17.6 13 4.2 17.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family KASH_CCD PF14662.6 CRK38724.1 - 9.5 6.0 23.7 0.41 10.5 12.5 2.1 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Rft-1 PF04506.13 CRK38726.1 - 7.6e-149 496.7 7.3 9.3e-149 496.5 7.3 1.0 1 0 0 1 1 1 1 Rft protein Polysacc_synt PF01943.17 CRK38726.1 - 8.5e-08 31.9 16.8 8.5e-08 31.9 16.8 2.5 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein Polysacc_synt_3 PF13440.6 CRK38726.1 - 0.0074 15.5 0.2 0.0074 15.5 0.2 2.6 3 0 0 3 3 3 2 Polysaccharide biosynthesis protein DEAD PF00270.29 CRK38728.1 - 1.9e-50 171.1 0.0 3.8e-50 170.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CRK38728.1 - 6.3e-32 110.2 0.1 3.8e-29 101.3 0.1 2.6 3 0 0 3 3 2 2 Helicase conserved C-terminal domain Na_H_Exchanger PF00999.21 CRK38728.1 - 1.3e-18 66.9 3.9 2e-18 66.4 3.9 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family ResIII PF04851.15 CRK38728.1 - 1.8e-05 24.8 0.6 3.7e-05 23.8 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit TFIIF_alpha PF05793.12 CRK38728.1 - 0.048 12.3 23.1 0.082 11.5 23.1 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) UTP25 PF06862.12 CRK38728.1 - 0.072 11.9 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 YrhC PF14143.6 CRK38728.1 - 0.15 12.1 1.3 1.4 9.0 0.4 2.5 2 0 0 2 2 2 0 YrhC-like protein Macoilin PF09726.9 CRK38728.1 - 3.4 6.1 10.4 4.8 5.6 10.4 1.1 1 0 0 1 1 1 0 Macoilin family RR_TM4-6 PF06459.12 CRK38728.1 - 5.4 6.8 17.5 11 5.8 17.5 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 CRK38728.1 - 7.3 4.8 15.6 12 4.0 15.6 1.3 1 0 0 1 1 1 0 CDC45-like protein CENP-N PF05238.13 CRK38728.1 - 9.8 5.4 14.4 15 4.7 14.4 1.2 1 0 0 1 1 1 0 Kinetochore protein CHL4 like NifU_N PF01592.16 CRK38734.1 - 6.2e-50 168.6 0.0 8.2e-50 168.3 0.0 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain UCH PF00443.29 CRK38736.1 - 3.3e-36 125.1 0.0 4.5e-36 124.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 CRK38736.1 - 1.2e-21 76.2 0.1 6.9e-10 38.6 0.1 2.6 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.6 CRK38736.1 - 4e-17 62.8 0.0 1.2e-15 58.0 0.0 2.6 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Ribosomal_L33 PF00471.20 CRK38736.1 - 0.029 14.8 2.3 2.5 8.6 0.8 2.4 2 0 0 2 2 2 0 Ribosomal protein L33 HORMA PF02301.18 CRK38738.1 - 7.4e-33 113.9 0.0 8.7e-33 113.7 0.0 1.0 1 0 0 1 1 1 1 HORMA domain ATG101 PF07855.12 CRK38738.1 - 0.00038 20.5 0.8 0.0018 18.3 0.8 1.9 1 1 0 1 1 1 1 Autophagy-related protein 101 EspB PF05802.11 CRK38738.1 - 0.033 14.2 0.2 0.05 13.6 0.2 1.2 1 0 0 1 1 1 0 Enterobacterial EspB protein zf-RING_2 PF13639.6 CRK38739.1 - 0.0006 20.1 1.2 0.0006 20.1 1.2 3.4 3 0 0 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.6 CRK38739.1 - 0.003 17.5 0.3 0.003 17.5 0.3 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 CRK38739.1 - 0.016 15.3 0.4 0.016 15.3 0.4 2.9 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 CRK38739.1 - 0.025 14.5 0.4 0.025 14.5 0.4 2.8 3 0 0 3 3 3 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CRK38739.1 - 0.029 14.2 0.2 0.029 14.2 0.2 2.8 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CRK38739.1 - 0.031 14.2 0.2 0.031 14.2 0.2 3.1 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CRK38739.1 - 0.075 13.3 0.4 0.075 13.3 0.4 2.4 2 0 0 2 2 2 0 RING-H2 zinc finger domain RPE65 PF03055.15 CRK38741.1 - 2.7e-115 386.2 0.0 3.4e-115 385.9 0.0 1.1 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein p450 PF00067.22 CRK38741.1 - 5e-68 229.9 0.0 7.5e-68 229.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 BTP PF05232.12 CRK38741.1 - 0.16 12.1 1.0 0.35 11.0 1.0 1.5 1 0 0 1 1 1 0 Chlorhexidine efflux transporter Ferric_reduct PF01794.19 CRK38744.1 - 8.1e-24 84.1 7.8 8.1e-24 84.1 7.8 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 CRK38744.1 - 1.3e-14 54.6 0.0 2.2e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 CRK38744.1 - 1.4e-08 34.8 0.0 2.8e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 CRK38744.1 - 0.00015 22.4 0.0 0.00041 21.0 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DUF1418 PF07214.12 CRK38744.1 - 0.17 11.8 0.0 0.17 11.8 0.0 2.9 3 1 2 5 5 5 0 Protein of unknown function (DUF1418) Ctr PF04145.15 CRK38746.1 - 9e-38 130.2 0.4 1.1e-37 130.0 0.4 1.1 1 0 0 1 1 1 1 Ctr copper transporter family SelP_N PF04592.14 CRK38748.1 - 0.19 11.1 5.1 0.24 10.8 5.1 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region TcA_TcB_BD PF18276.1 CRK38779.1 - 3.9e-111 370.8 0.0 5e-111 370.4 0.0 1.1 1 0 0 1 1 1 1 Tc toxin complex TcA C-terminal TcB-binding domain Legionella_OMP PF05150.12 CRK38779.1 - 0.16 10.8 0.0 14 4.5 0.0 2.3 2 0 0 2 2 2 0 Legionella pneumophila major outer membrane protein precursor AHH PF14412.6 CRK38781.1 - 0.0013 18.7 0.1 0.0026 17.8 0.1 1.4 1 0 0 1 1 1 1 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH DUF5353 PF17304.2 CRK38781.1 - 0.09 12.5 0.2 0.21 11.4 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5353) Trypan_PARP PF05887.11 CRK38781.1 - 0.25 11.3 43.8 0.086 12.8 28.9 2.3 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) Ndc1_Nup PF09531.10 CRK38781.1 - 0.71 8.5 3.9 0.83 8.3 3.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Carb_anhydrase PF00194.21 CRK38787.1 - 5.1e-11 42.6 0.0 5.2e-11 42.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase GYF_2 PF14237.6 CRK38787.1 - 0.21 11.4 0.0 0.39 10.6 0.0 1.4 1 0 0 1 1 1 0 GYF domain 2 UBA_2 PF08587.11 CRK38788.1 - 1.5e-16 60.2 0.4 3.2e-16 59.2 0.4 1.6 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) PI-PLC-C1 PF16670.5 CRK38789.1 - 1e-31 110.2 0.0 1.1e-31 110.1 0.0 1.0 1 0 0 1 1 1 1 Phosphoinositide phospholipase C, Ca2+-dependent E1_dh PF00676.20 CRK38791.1 - 2e-118 394.7 4.5 2.3e-74 250.0 1.0 2.1 2 0 0 2 2 2 2 Dehydrogenase E1 component DXP_synthase_N PF13292.6 CRK38791.1 - 0.002 17.4 0.1 0.0037 16.5 0.1 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase DNA_ligase_A_C PF04679.15 CRK38791.1 - 0.016 15.8 0.0 0.091 13.4 0.0 2.3 2 0 0 2 2 2 0 ATP dependent DNA ligase C terminal region Voltage_CLC PF00654.20 CRK38793.1 - 3.7e-18 65.9 6.4 5.1e-18 65.4 6.4 1.2 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 CRK38793.1 - 0.00029 21.2 0.0 0.14 12.6 0.0 2.6 2 0 0 2 2 2 2 CBS domain LacI PF00356.21 CRK38793.1 - 0.087 12.6 1.1 0.18 11.7 1.1 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family DUF2062 PF09835.9 CRK38793.1 - 0.092 12.6 1.6 0.14 12.0 1.6 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) Myc_N PF01056.18 CRK38801.1 - 0.021 14.7 0.7 0.023 14.6 0.7 1.0 1 0 0 1 1 1 0 Myc amino-terminal region HgmA PF04209.13 CRK38808.1 - 8.3e-11 41.2 0.0 8.8e-11 41.2 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Amidase PF01425.21 CRK38810.1 - 4e-78 263.4 0.0 5.1e-78 263.0 0.0 1.1 1 0 0 1 1 1 1 Amidase zf-CCCH PF00642.24 CRK38811.1 - 2.4e-16 59.2 24.7 1.5e-06 27.9 0.9 4.4 3 1 1 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CRK38811.1 - 4.4e-13 48.8 27.5 1.5e-05 24.9 4.3 4.4 4 0 0 4 4 4 4 Zinc finger domain Torus PF16131.5 CRK38811.1 - 5.6e-10 39.9 20.0 0.00054 20.6 1.1 4.2 1 1 3 4 4 4 4 Torus domain zf-CCCH_4 PF18044.1 CRK38811.1 - 2.2e-05 24.1 1.4 2.2e-05 24.1 1.4 4.3 4 0 0 4 4 4 2 CCCH-type zinc finger GRP PF07172.11 CRK38811.1 - 0.11 13.1 18.1 0.19 12.5 18.1 1.3 1 0 0 1 1 1 0 Glycine rich protein family Pyr_redox_2 PF07992.14 CRK38812.1 - 1.3e-08 34.4 0.0 1.6e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase CdvA PF18822.1 CRK38812.1 - 0.025 14.4 0.0 0.18 11.6 0.0 2.0 2 0 0 2 2 2 0 CdvA-like coiled-coil domain Pyr_redox_3 PF13738.6 CRK38812.1 - 0.047 12.9 0.0 0.056 12.7 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Attacin_N PF03768.15 CRK38812.1 - 0.1 12.8 0.1 0.24 11.5 0.1 1.7 1 1 0 1 1 1 0 Attacin, N-terminal region H2O2_YaaD PF03883.14 CRK38818.1 - 0.044 13.3 0.0 0.051 13.1 0.0 1.0 1 0 0 1 1 1 0 Peroxide stress protein YaaA FAM209 PF15206.6 CRK38819.1 - 0.15 11.8 0.0 0.18 11.6 0.0 1.1 1 0 0 1 1 1 0 FAM209 family Aldo_ket_red PF00248.21 CRK38830.1 - 2e-49 168.4 0.0 3.8e-47 160.9 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Death PF00531.22 CRK38830.1 - 0.005 17.0 0.0 5.9 7.1 0.0 3.0 3 0 0 3 3 3 2 Death domain LysM PF01476.20 CRK38830.1 - 0.031 14.4 0.1 0.059 13.5 0.1 1.4 1 0 0 1 1 1 0 LysM domain Ferric_reduct PF01794.19 CRK38831.1 - 2.7e-22 79.2 14.5 2.7e-22 79.2 14.5 2.4 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 CRK38831.1 - 9.5e-09 35.3 0.0 1.8e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain DUF3093 PF11292.8 CRK38831.1 - 0.017 15.4 5.9 0.017 15.4 5.9 2.5 2 2 0 2 2 2 0 Protein of unknown function (DUF3093) DUF1761 PF08570.10 CRK38831.1 - 0.051 13.8 8.2 0.068 13.4 5.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1761) PsbN PF02468.15 CRK38831.1 - 0.31 10.9 0.0 0.31 10.9 0.0 3.1 3 0 0 3 3 3 0 Photosystem II reaction centre N protein (psbN) MLANA PF14991.6 CRK38831.1 - 0.4 11.0 2.2 0.69 10.2 1.1 1.8 1 1 1 2 2 2 0 Protein melan-A DUF2070 PF09843.9 CRK38831.1 - 1.7 6.9 12.6 2.3 6.4 12.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Bestrophin PF01062.21 CRK38833.1 - 2.4e-33 115.8 0.9 4.2e-33 115.0 0.9 1.3 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel T6SS_VasE PF05936.12 CRK38833.1 - 0.12 11.0 0.1 0.17 10.6 0.1 1.2 1 0 0 1 1 1 0 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE Dus PF01207.17 CRK38835.1 - 2e-11 43.5 0.1 2.2e-11 43.4 0.1 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Aldo_ket_red PF00248.21 CRK38836.1 - 6.2e-43 147.1 0.3 3.5e-42 144.6 0.3 1.8 1 1 0 1 1 1 1 Aldo/keto reductase family CW_binding_2 PF04122.12 CRK38836.1 - 0.11 13.2 0.1 0.22 12.2 0.1 1.5 1 0 0 1 1 1 0 Putative cell wall binding repeat 2 Velvet PF11754.8 CRK38837.1 - 2.5e-05 24.4 0.1 8.4e-05 22.6 0.1 1.7 1 1 0 1 1 1 1 Velvet factor COesterase PF00135.28 CRK38838.1 - 6.3e-28 97.9 0.0 9.5e-28 97.3 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family fn3_5 PF06280.12 CRK38838.1 - 7.2e-17 62.1 0.0 1.4e-16 61.3 0.0 1.5 1 0 0 1 1 1 1 Fn3-like domain Peptidase_S8 PF00082.22 CRK38838.1 - 3.1e-15 56.2 0.0 4.3e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 Subtilase family FlgD_ig PF13860.6 CRK38838.1 - 0.0003 20.6 0.1 0.0033 17.3 0.0 2.3 2 0 0 2 2 2 1 FlgD Ig-like domain BolA PF01722.18 CRK38840.1 - 1.1e-09 38.4 0.0 2.7e-09 37.2 0.0 1.7 1 1 0 1 1 1 1 BolA-like protein DUF4217 PF13959.6 CRK38855.1 - 4.1e-19 68.6 1.1 5.4e-19 68.2 0.7 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) DUF3337 PF11816.8 CRK38856.1 - 3.4e-55 186.6 0.0 7.5e-55 185.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 CRK38856.1 - 1.9e-09 38.0 1.3 0.035 15.0 0.0 3.6 3 0 0 3 3 3 3 WD domain, G-beta repeat HET PF06985.11 CRK38858.1 - 6.1e-30 104.5 0.0 1.1e-29 103.6 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Mitofilin PF09731.9 CRK38865.1 - 1.1e-148 496.9 15.7 1.5e-125 420.5 19.2 2.3 1 1 1 2 2 2 2 Mitochondrial inner membrane protein Ras PF00071.22 CRK38865.1 - 6.3e-58 195.0 0.3 1.2e-57 194.0 0.3 1.5 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CRK38865.1 - 2.8e-35 121.1 0.1 7.2e-35 119.8 0.1 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CRK38865.1 - 2.6e-14 53.0 0.1 5.2e-14 52.1 0.1 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CRK38865.1 - 3.8e-06 26.4 0.0 7.9e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CRK38865.1 - 8.8e-06 25.4 0.0 2e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CRK38865.1 - 1.7e-05 24.9 0.4 4.3e-05 23.6 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF2959 PF11172.8 CRK38865.1 - 0.00023 21.4 3.4 0.00065 19.9 3.4 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2959) RsgA_GTPase PF03193.16 CRK38865.1 - 0.0013 18.6 1.5 0.76 9.7 0.2 2.8 1 1 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 CRK38865.1 - 0.48 10.8 0.0 0.48 10.8 0.0 2.7 2 1 0 2 2 2 0 AAA ATPase domain NACHT PF05729.12 CRK38866.1 - 0.00066 19.6 0.1 0.0055 16.6 0.1 2.2 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 CRK38866.1 - 0.0017 18.8 0.0 0.015 15.7 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain Ank_2 PF12796.7 CRK38866.1 - 0.0018 18.9 0.0 0.013 16.1 0.0 2.4 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CRK38866.1 - 0.0051 17.2 0.0 0.24 12.1 0.0 3.6 4 0 0 4 4 4 1 Ankyrin repeat Sec16 PF12932.7 CRK38866.1 - 0.0073 16.9 0.0 0.016 15.8 0.0 1.6 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region AAA_22 PF13401.6 CRK38866.1 - 0.028 14.7 0.0 0.11 12.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain Ank_4 PF13637.6 CRK38866.1 - 0.044 14.4 0.0 1.8 9.2 0.0 3.2 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Ank PF00023.30 CRK38866.1 - 0.094 13.2 0.0 1.8 9.2 0.0 2.9 2 0 0 2 2 2 0 Ankyrin repeat TsaE PF02367.17 CRK38866.1 - 0.17 11.8 0.0 1 9.3 0.0 2.3 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE KAP_NTPase PF07693.14 CRK38866.1 - 0.33 10.2 4.7 2.7 7.2 0.0 2.7 3 0 0 3 3 3 0 KAP family P-loop domain DUF3818 PF12825.7 CRK38868.1 - 3.3e-16 59.3 0.1 3.5e-16 59.2 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) DUF3802 PF12290.8 CRK38868.1 - 0.021 15.4 0.0 0.025 15.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3802) Methyltransf_23 PF13489.6 CRK38884.1 - 1e-16 61.2 0.0 1.6e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK38884.1 - 1.1e-07 32.5 0.0 2.3e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK38884.1 - 1e-06 29.4 0.0 2.5e-06 28.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CRK38884.1 - 6.1e-06 26.8 0.0 1.1e-05 25.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK38884.1 - 5.6e-05 23.0 0.0 0.00066 19.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 CRK38884.1 - 0.00087 18.8 0.0 0.0015 18.0 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.13 CRK38884.1 - 0.01 15.2 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 CRK38884.1 - 0.029 13.9 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_2 PF00891.18 CRK38884.1 - 0.17 11.1 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_23 PF13489.6 CRK38886.1 - 3.7e-20 72.4 0.0 5.6e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK38886.1 - 9.3e-09 35.9 0.0 8.2e-08 32.9 0.0 2.6 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK38886.1 - 4.7e-06 27.3 0.0 9.4e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK38886.1 - 1.6e-05 24.7 0.0 4.2e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CRK38886.1 - 0.00024 21.7 0.0 0.0012 19.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 CRK38886.1 - 0.18 11.9 0.0 0.42 10.7 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase p450 PF00067.22 CRK38888.1 - 8.6e-38 130.3 0.0 2.3e-37 128.8 0.0 1.6 2 0 0 2 2 2 1 Cytochrome P450 DUF3112 PF11309.8 CRK38891.1 - 1.7e-14 53.8 0.1 1.8e-14 53.7 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3112) YvrJ PF12841.7 CRK38891.1 - 0.017 14.7 0.1 0.023 14.2 0.1 1.2 1 0 0 1 1 1 0 YvrJ protein family ATP_sub_h PF10775.9 CRK38892.1 - 2.8e-22 78.5 1.7 3.9e-22 78.0 1.7 1.2 1 0 0 1 1 1 1 ATP synthase complex subunit h Transket_pyr PF02779.24 CRK38896.1 - 1.3e-45 155.2 0.0 1.8e-45 154.8 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 CRK38896.1 - 3e-35 120.8 0.0 7.8e-35 119.5 0.0 1.8 2 0 0 2 2 2 1 Transketolase, C-terminal domain FtsA PF14450.6 CRK38896.1 - 0.036 14.5 0.0 0.13 12.6 0.0 1.9 2 0 0 2 2 2 0 Cell division protein FtsA Sterol_MT_C PF08498.10 CRK38897.1 - 2.4e-23 82.2 0.2 3.6e-23 81.7 0.2 1.2 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal RAC_head PF16717.5 CRK38898.1 - 1.1e-29 103.2 1.5 1.1e-29 103.2 1.5 4.3 4 1 1 5 5 5 1 Ribosome-associated complex head domain DnaJ PF00226.31 CRK38898.1 - 5.5e-18 64.8 1.1 2e-17 63.1 1.1 2.0 1 0 0 1 1 1 1 DnaJ domain RRM_1 PF00076.22 CRK38898.1 - 8.1e-08 32.0 0.2 1.1e-06 28.4 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CRK38898.1 - 0.0036 17.3 0.0 0.0079 16.2 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 CRK38898.1 - 0.018 15.1 0.0 0.018 15.1 0.0 3.3 2 1 1 3 3 3 0 RNA binding motif V_ATPase_I PF01496.19 CRK38898.1 - 2.1 6.2 6.4 3.3 5.5 6.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PAN_4 PF14295.6 CRK38900.1 - 0.0067 16.3 1.6 0.015 15.2 1.6 1.5 1 0 0 1 1 1 1 PAN domain DUF1691 PF07950.11 CRK38902.1 - 7.4e-39 132.8 6.7 1.6e-33 115.6 4.6 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) FAR1 PF03101.15 CRK38914.1 - 0.00018 22.1 2.0 0.00018 22.1 2.0 2.3 2 1 0 2 2 2 1 FAR1 DNA-binding domain AFT PF08731.11 CRK38914.1 - 0.017 15.5 0.7 0.017 15.5 0.7 2.5 2 1 0 2 2 2 0 Transcription factor AFT DBD_Tnp_Mut PF03108.15 CRK38914.1 - 0.15 12.0 4.7 2.7 8.0 1.1 3.0 1 1 1 2 2 2 0 MuDR family transposase Peptidase_U57 PF05582.12 CRK38914.1 - 3.1 7.0 8.6 4.4 6.5 8.6 1.2 1 0 0 1 1 1 0 YabG peptidase U57 RR_TM4-6 PF06459.12 CRK38914.1 - 8.6 6.1 12.4 15 5.3 12.4 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MutS_V PF00488.21 CRK38915.1 - 2.4e-49 167.9 0.4 4.5e-49 167.0 0.4 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 CRK38915.1 - 1.2e-22 81.1 0.0 2.5e-22 80.0 0.0 1.6 1 1 0 1 1 1 1 MutS domain III MutS_II PF05188.17 CRK38915.1 - 2.3e-06 27.9 0.0 6.6e-06 26.5 0.0 1.7 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 CRK38915.1 - 4.8e-06 26.8 0.1 9.5e-06 25.9 0.1 1.5 1 0 0 1 1 1 1 MutS family domain IV DUF2093 PF09866.9 CRK38915.1 - 0.2 11.1 0.5 0.49 9.9 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2093) ADC PF06314.11 CRK38916.1 - 0.00073 19.2 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) HET PF06985.11 CRK38918.1 - 8.8e-29 100.7 0.2 1.5e-28 100.0 0.2 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SLT_L PF14718.6 CRK38918.1 - 0.027 14.6 1.5 0.057 13.5 1.5 1.5 1 0 0 1 1 1 0 Soluble lytic murein transglycosylase L domain Methyltransf_11 PF08241.12 CRK38919.1 - 3.8e-11 43.5 0.0 7.7e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain WBS_methylT PF12589.8 CRK38919.1 - 8.9e-11 42.4 2.7 2.1e-10 41.2 2.7 1.6 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_25 PF13649.6 CRK38919.1 - 1.1e-10 42.1 0.0 2.5e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK38919.1 - 7.5e-05 23.4 0.0 0.00029 21.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 CRK38919.1 - 0.00083 19.2 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 CRK38919.1 - 0.0021 17.9 0.0 0.0033 17.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CRK38919.1 - 0.015 15.2 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 CRK38919.1 - 0.021 14.1 0.0 0.18 11.1 0.0 2.0 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Methyltransf_33 PF10017.9 CRK38919.1 - 0.027 13.6 0.0 0.041 13.0 0.0 1.2 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Methyltransf_2 PF00891.18 CRK38919.1 - 0.05 12.9 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain Erv26 PF04148.13 CRK38920.1 - 3.8e-90 301.2 3.1 4.3e-90 301.0 3.1 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 Cytochrom_C_asm PF01578.20 CRK38920.1 - 0.02 14.7 1.7 0.02 14.7 1.7 1.7 2 1 0 2 2 2 0 Cytochrome C assembly protein DUF3169 PF11368.8 CRK38920.1 - 0.21 11.1 3.8 0.3 10.6 3.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3169) Dynamin_N PF00350.23 CRK38921.1 - 4e-31 108.3 0.0 7.8e-31 107.4 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 CRK38921.1 - 1.8e-14 53.7 0.0 1.5e-13 50.6 0.0 2.3 2 1 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.23 CRK38921.1 - 3.2e-05 24.0 0.1 9e-05 22.5 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.27 CRK38921.1 - 0.041 14.4 0.0 0.11 13.1 0.0 1.7 1 0 0 1 1 1 0 ABC transporter GED PF02212.18 CRK38921.1 - 0.15 12.2 0.4 0.39 10.9 0.4 1.7 1 0 0 1 1 1 0 Dynamin GTPase effector domain ADH_zinc_N PF00107.26 CRK38922.1 - 2.1e-22 79.5 0.1 3.2e-22 78.9 0.1 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CRK38922.1 - 3.2e-09 37.9 0.0 5.8e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 CRK38922.1 - 0.014 15.3 0.0 0.038 13.9 0.0 1.8 1 1 1 2 2 2 0 N-terminal domain of oxidoreductase Pkinase PF00069.25 CRK38924.1 - 1.7e-08 34.1 0.0 6.6e-05 22.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase PF00069.25 CRK38925.1 - 4.3e-08 32.9 0.0 8.4e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK38925.1 - 3.5e-05 23.2 0.0 9.5e-05 21.8 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 CRK38925.1 - 0.087 11.8 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase p450 PF00067.22 CRK38926.1 - 1.6e-58 198.6 0.0 2.4e-58 198.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.25 CRK38926.1 - 2.6e-47 161.4 0.0 3.6e-47 161.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK38926.1 - 1.8e-28 99.6 0.0 2.9e-28 98.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase YTH PF04146.15 CRK38926.1 - 8.7e-26 90.8 0.0 2e-25 89.7 0.0 1.6 1 1 0 1 1 1 1 YT521-B-like domain Kdo PF06293.14 CRK38926.1 - 3.9e-06 26.4 0.0 7.4e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CRK38926.1 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like GMC_oxred_N PF00732.19 CRK38928.1 - 3e-24 85.9 0.2 6.2e-18 65.2 0.0 2.2 1 1 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 CRK38928.1 - 2e-21 77.0 0.0 3.9e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Dioxygenase_C PF00775.21 CRK38930.1 - 0.041 13.3 0.7 0.21 11.0 0.7 2.0 1 1 0 1 1 1 0 Dioxygenase Na_H_Exchanger PF00999.21 CRK38932.1 - 6.1e-55 186.6 44.4 9.3e-55 186.0 44.4 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Usp PF00582.26 CRK38932.1 - 0.093 13.2 3.1 0.87 10.1 3.1 2.2 1 1 0 1 1 1 0 Universal stress protein family Aminotran_5 PF00266.19 CRK38934.1 - 1.2e-16 60.6 0.0 6.8e-16 58.2 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 CRK38934.1 - 0.00012 20.8 0.0 0.00032 19.4 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme ADH_zinc_N PF00107.26 CRK38936.1 - 1.1e-11 44.8 0.0 2.1e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CRK38936.1 - 6.6e-06 26.0 0.0 1.2e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 CRK38936.1 - 0.00022 22.3 0.0 0.00039 21.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 CRK38936.1 - 0.0022 17.9 0.0 0.0045 16.9 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase Glu_dehyd_C PF16912.5 CRK38936.1 - 0.059 12.8 0.0 0.096 12.2 0.0 1.3 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus MRPL52 PF18699.1 CRK38937.1 - 0.17 12.1 0.0 4.1 7.7 0.0 2.2 2 0 0 2 2 2 0 Mitoribosomal protein mL52 Bys1 PF04681.12 CRK38939.1 - 8.8e-06 25.7 0.1 1.3e-05 25.2 0.0 1.3 1 1 0 1 1 1 1 Blastomyces yeast-phase-specific protein Bys1 PF04681.12 CRK38944.1 - 8.9e-11 42.0 0.2 1.1e-10 41.7 0.2 1.1 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein Prok-E2_B PF14461.6 CRK38945.1 - 0.16 11.7 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B Glyco_hydro_7 PF00840.20 CRK38948.1 - 4.2e-171 569.5 3.5 4.7e-171 569.3 3.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Nucleotid_trans PF03407.16 CRK38949.1 - 0.00048 20.2 0.0 0.00072 19.6 0.0 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Glyco_transf_34 PF05637.12 CRK38949.1 - 0.023 14.4 0.5 0.036 13.8 0.5 1.3 1 0 0 1 1 1 0 galactosyl transferase GMA12/MNN10 family Antimicrobial_5 PF08026.11 CRK38949.1 - 0.41 10.8 2.2 1.3 9.1 2.2 1.9 1 0 0 1 1 1 0 Bee antimicrobial peptide Cyclase PF04199.13 CRK38950.1 - 2.9e-11 43.8 0.0 4.5e-11 43.1 0.0 1.3 1 1 0 1 1 1 1 Putative cyclase K_oxygenase PF13434.6 CRK38951.1 - 4.8e-05 22.7 0.0 0.00011 21.5 0.0 1.5 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 CRK38951.1 - 0.00011 21.5 0.4 0.0042 16.3 0.4 2.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 CRK38951.1 - 0.00041 20.4 0.0 0.11 12.6 0.0 2.3 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.6 CRK38951.1 - 0.00076 18.8 1.1 0.21 10.8 0.0 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 CRK38951.1 - 0.0025 17.2 0.0 0.0043 16.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 CRK38951.1 - 0.012 14.8 0.4 5 6.3 0.1 3.1 3 0 0 3 3 3 0 FAD binding domain tRNA_int_endo PF01974.17 CRK38951.1 - 0.049 13.7 2.2 7.4 6.7 0.1 3.0 3 0 0 3 3 3 0 tRNA intron endonuclease, catalytic C-terminal domain LEA_2 PF03168.13 CRK38951.1 - 0.094 13.3 0.3 12 6.5 0.0 2.4 2 0 0 2 2 2 0 Late embryogenesis abundant protein FMO-like PF00743.19 CRK38951.1 - 0.27 9.6 0.0 0.48 8.8 0.0 1.4 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like adh_short PF00106.25 CRK38953.1 - 7.6e-25 87.5 2.2 8.6e-23 80.8 0.0 2.7 2 1 1 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 CRK38953.1 - 2.8e-23 82.7 0.0 5.6e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1689 PF07954.11 CRK38953.1 - 0.048 14.1 0.0 0.093 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1689) Abhydrolase_1 PF00561.20 CRK38955.1 - 9e-12 45.2 0.0 1.4e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CRK38955.1 - 4.4e-05 24.2 0.4 0.00042 21.0 0.1 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CRK38955.1 - 0.0067 15.7 0.0 0.009 15.3 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 CRK38955.1 - 0.025 14.2 0.0 0.038 13.6 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Ndr PF03096.14 CRK38955.1 - 0.04 12.6 0.0 0.054 12.2 0.0 1.2 1 0 0 1 1 1 0 Ndr family UPF0227 PF05728.12 CRK38955.1 - 0.058 13.3 0.0 0.086 12.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) MFS_1 PF07690.16 CRK38957.1 - 1.8e-27 96.2 49.1 1.8e-27 96.2 49.1 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Homeobox_KN PF05920.11 CRK38958.1 - 3.7e-13 49.2 0.9 7.8e-13 48.1 0.9 1.6 1 0 0 1 1 1 1 Homeobox KN domain zf-C2H2 PF00096.26 CRK38958.1 - 4.1e-06 27.0 22.6 0.011 16.2 2.5 4.6 4 0 0 4 4 4 2 Zinc finger, C2H2 type Homeodomain PF00046.29 CRK38958.1 - 2.9e-05 23.8 0.6 6.2e-05 22.8 0.6 1.5 1 0 0 1 1 1 1 Homeodomain zf-C2H2_4 PF13894.6 CRK38958.1 - 6.5e-05 23.4 23.3 0.0005 20.7 2.3 4.9 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 CRK38958.1 - 0.094 13.4 1.5 4.8 7.9 0.5 2.4 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-met PF12874.7 CRK38958.1 - 1.7 9.1 7.7 13 6.3 0.3 4.2 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Sugar_tr PF00083.24 CRK38959.1 - 3.1e-63 214.2 18.5 4.1e-63 213.8 18.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter HsbA PF12296.8 CRK38959.1 - 3.8e-19 69.3 13.0 5.2e-18 65.6 11.2 2.3 2 0 0 2 2 2 1 Hydrophobic surface binding protein A MFS_1 PF07690.16 CRK38959.1 - 1.2e-14 54.1 27.3 1.8e-14 53.5 27.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_10 PF00331.20 CRK38960.1 - 4.3e-67 226.5 0.0 5.3e-67 226.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Glyco_hydro_42 PF02449.15 CRK38960.1 - 0.029 13.7 0.0 0.051 12.9 0.0 1.3 1 0 0 1 1 1 0 Beta-galactosidase Pec_lyase_C PF00544.19 CRK38961.1 - 1.1e-39 136.2 6.2 1.5e-39 135.8 6.2 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 CRK38961.1 - 0.00013 21.8 7.9 0.0017 18.2 7.9 2.3 1 1 0 1 1 1 1 Right handed beta helix region Cation_ATPase_C PF00689.21 CRK38962.1 - 3.8e-46 157.1 6.8 3.8e-46 157.1 6.8 2.2 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 CRK38962.1 - 1.2e-35 122.7 0.6 1.2e-35 122.7 0.6 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 CRK38962.1 - 1e-21 76.8 0.0 2e-21 75.9 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 CRK38962.1 - 2e-13 49.8 0.0 3.5e-10 39.4 0.0 2.8 2 0 0 2 2 2 2 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 CRK38962.1 - 1.1e-12 48.8 0.0 2.8e-12 47.4 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF3899 PF13038.6 CRK38962.1 - 0.074 13.6 0.0 0.074 13.6 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3899) DUF3429 PF11911.8 CRK38962.1 - 3.1 8.1 5.9 0.63 10.3 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3429) LptF_LptG PF03739.14 CRK38962.1 - 5.8 5.7 10.8 0.12 11.2 3.5 1.8 2 0 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG TctB PF07331.11 CRK38962.1 - 6.1 7.1 10.9 8.5 6.7 2.2 3.7 3 0 0 3 3 3 0 Tripartite tricarboxylate transporter TctB family Cep57_MT_bd PF06657.13 CRK38963.1 - 0.057 13.9 0.8 0.073 13.5 0.8 1.1 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 MFS_1 PF07690.16 CRK38964.1 - 2e-32 112.5 81.5 1e-20 74.0 46.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily CFEM PF05730.11 CRK38965.1 - 0.011 15.8 20.9 0.13 12.3 1.7 3.5 3 0 0 3 3 3 0 CFEM domain TAFA PF12020.8 CRK38965.1 - 0.023 15.1 0.1 0.083 13.4 0.1 2.0 1 0 0 1 1 1 0 TAFA family Gram_pos_anchor PF00746.21 CRK38965.1 - 0.029 14.3 0.7 0.029 14.3 0.7 2.0 2 0 0 2 2 2 0 LPXTG cell wall anchor motif PTP_tm PF18861.1 CRK38965.1 - 0.17 11.9 4.1 0.3 11.1 4.1 1.3 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J DUF2613 PF11021.8 CRK38965.1 - 0.49 10.5 5.8 2.1 8.5 5.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) Cys_rich_CWC PF14375.6 CRK38965.1 - 7.1 7.1 12.8 2.8 8.4 1.5 3.6 3 0 0 3 3 3 0 Cysteine-rich CWC Glyco_hydro_28 PF00295.17 CRK38966.1 - 2.6e-35 122.0 1.1 3.6e-35 121.6 1.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 RRM_1 PF00076.22 CRK38967.1 - 3e-90 296.1 0.0 3.2e-16 58.9 0.0 6.2 6 0 0 6 6 6 6 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CRK38967.1 - 1.8e-11 43.9 1.0 0.005 16.8 0.1 5.5 6 0 0 6 6 6 2 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 CRK38967.1 - 6.9e-11 41.9 0.0 0.12 12.2 0.0 5.8 6 0 0 6 6 6 2 Occluded RNA-recognition motif RRM_3 PF08777.11 CRK38967.1 - 3.3e-10 39.9 0.2 0.004 17.2 0.0 4.0 6 0 0 6 6 6 2 RNA binding motif RRM_7 PF16367.5 CRK38967.1 - 4.8e-10 39.4 0.4 0.12 12.6 0.0 5.4 6 0 0 6 6 6 2 RNA recognition motif RRM_5 PF13893.6 CRK38967.1 - 3e-06 26.8 0.0 0.14 11.7 0.0 2.9 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 CRK38967.1 - 0.005 16.5 1.1 18 5.1 0.0 4.1 4 0 0 4 4 4 2 Ribonuclease B OB domain EF-hand_1 PF00036.32 CRK38967.1 - 0.16 11.6 0.3 29 4.5 0.0 2.6 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.6 CRK38967.1 - 0.19 11.7 0.1 41 4.5 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain Ecm29 PF13001.7 CRK38969.1 - 3.4e-69 233.8 0.0 4.4e-69 233.5 0.0 1.0 1 0 0 1 1 1 1 Proteasome stabiliser Ecm29 PF13001.7 CRK38970.1 - 4.3e-75 253.3 0.7 3.2e-40 138.3 0.0 3.9 3 1 1 4 4 4 2 Proteasome stabiliser Pkinase PF00069.25 CRK38970.1 - 7.8e-64 215.6 0.0 1.3e-63 214.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK38970.1 - 3.6e-47 160.8 0.0 7.2e-47 159.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Thioredoxin_7 PF13899.6 CRK38970.1 - 1.3e-16 60.6 0.3 3.6e-16 59.1 0.3 1.8 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.6 CRK38970.1 - 3.6e-15 55.5 1.1 3.6e-14 52.3 0.1 2.9 2 0 0 2 2 2 1 UBA-like domain UBX PF00789.20 CRK38970.1 - 2.6e-09 37.1 0.0 6.1e-09 36.0 0.0 1.7 1 0 0 1 1 1 1 UBX domain HEAT_2 PF13646.6 CRK38970.1 - 7.1e-06 26.3 5.3 0.21 12.0 0.0 6.0 5 0 0 5 5 5 1 HEAT repeats MMS19_C PF12460.8 CRK38970.1 - 0.021 14.0 0.0 8.5 5.4 0.0 3.9 5 0 0 5 5 5 0 RNAPII transcription regulator C-terminal CLASP_N PF12348.8 CRK38970.1 - 0.084 12.4 0.2 6.2 6.3 0.0 2.8 2 1 0 2 2 2 0 CLASP N terminal SBD_N PF07005.11 CRK38971.1 - 8.4e-61 205.6 1.8 8.4e-61 205.6 1.8 1.9 2 0 0 2 2 2 1 Sugar-binding N-terminal domain NBD_C PF17042.5 CRK38971.1 - 9.3e-42 143.4 4.7 9.3e-42 143.4 4.7 2.0 2 0 0 2 2 2 1 Nucleotide-binding C-terminal domain Iso_dh PF00180.20 CRK38972.1 - 2.9e-82 276.6 0.0 3.5e-82 276.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Fungal_trans_2 PF11951.8 CRK38973.1 - 1.1e-11 44.2 0.1 4e-07 29.2 0.0 2.9 3 0 0 3 3 3 2 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK38973.1 - 1.2e-08 34.9 22.5 8.1e-07 29.1 9.7 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain GMC_oxred_N PF00732.19 CRK38974.1 - 9.3e-26 90.9 0.0 4.2e-18 65.7 0.0 2.1 1 1 1 2 2 2 2 GMC oxidoreductase Lycopene_cycl PF05834.12 CRK38974.1 - 0.13 11.3 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_8 PF13450.6 CRK38974.1 - 0.16 12.2 0.3 0.52 10.6 0.1 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 CRK38974.1 - 0.19 11.7 0.0 0.57 10.2 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding p450 PF00067.22 CRK38975.1 - 1.7e-56 191.9 0.0 2.3e-56 191.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CLTH PF10607.9 CRK38976.1 - 1.6e-29 102.7 0.0 2.9e-29 101.9 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 CRK38976.1 - 3.5e-09 36.5 2.8 6.3e-09 35.7 2.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CRK38976.1 - 3.3e-06 27.0 1.9 5.7e-06 26.2 1.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CRK38976.1 - 5.3e-05 23.0 2.0 8.8e-05 22.3 2.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CRK38976.1 - 0.00021 21.6 3.1 0.00035 20.8 3.1 1.4 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 CRK38976.1 - 0.00033 20.4 3.3 0.00062 19.6 3.3 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 CRK38976.1 - 0.0013 18.5 3.7 0.0025 17.6 3.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CRK38976.1 - 0.0014 18.4 3.3 0.0026 17.6 3.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CRK38976.1 - 0.0029 17.7 1.2 0.0063 16.6 1.2 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Rtf2 PF04641.12 CRK38976.1 - 0.0074 15.7 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_4 PF14570.6 CRK38976.1 - 0.025 14.4 1.5 0.041 13.7 1.5 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C2HC5 PF06221.13 CRK38976.1 - 0.11 12.5 0.2 0.22 11.6 0.2 1.5 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type Laminin_I PF06008.14 CRK38976.1 - 0.23 11.1 3.4 1.2 8.8 0.3 2.1 2 0 0 2 2 2 0 Laminin Domain I Mpv17_PMP22 PF04117.12 CRK38978.1 - 5.8e-24 84.1 1.2 1.1e-23 83.2 1.2 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family Mpv17_PMP22 PF04117.12 CRK38979.1 - 5.8e-24 84.1 1.2 1.1e-23 83.2 1.2 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family CS PF04969.16 CRK38980.1 - 4.4e-15 56.5 0.0 7.8e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 CS domain LIM_bind PF01803.16 CRK38980.1 - 0.01 15.4 1.3 0.015 14.9 1.3 1.2 1 0 0 1 1 1 0 LIM-domain binding protein MAT1 PF06391.13 CRK38981.1 - 3.7e-34 118.4 8.3 4.8e-34 118.0 8.3 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 CRK38981.1 - 5.3e-29 99.9 7.9 8.1e-29 99.3 7.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CRK38981.1 - 0.0077 16.1 2.8 0.02 14.8 2.8 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CRK38981.1 - 0.0095 15.8 4.2 0.021 14.6 4.2 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CRK38981.1 - 0.062 13.6 4.5 0.11 12.8 4.5 1.4 1 0 0 1 1 1 0 Ring finger domain Zn_ribbon_17 PF17120.5 CRK38981.1 - 0.095 12.3 1.1 0.19 11.3 1.1 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 CRK38981.1 - 0.22 11.5 8.5 2 8.4 8.7 2.1 1 1 1 2 2 2 0 zinc-RING finger domain MRP-S26 PF14943.6 CRK38981.1 - 0.51 10.2 13.1 0.81 9.6 13.1 1.2 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 zf-RING_UBOX PF13445.6 CRK38981.1 - 0.57 10.3 4.5 1.1 9.3 4.5 1.4 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_6 PF14835.6 CRK38981.1 - 0.8 9.6 3.5 1.9 8.4 0.7 2.7 1 1 1 2 2 2 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 CRK38981.1 - 5.1 7.0 9.3 41 4.1 9.8 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain ANTH PF07651.16 CRK38982.1 - 1.6e-25 89.6 0.0 1.9e-25 89.4 0.0 1.0 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 CRK38982.1 - 2.2e-07 31.0 0.0 2.5e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 ENTH domain GST_N_2 PF13409.6 CRK38994.1 - 6.4e-09 36.0 0.1 9.9e-09 35.4 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 CRK38994.1 - 6.5e-09 36.1 0.0 1.4e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CRK38994.1 - 1.7e-06 27.9 0.1 3.4e-06 27.0 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CRK38994.1 - 0.00036 20.7 0.0 0.00063 19.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CRK38994.1 - 0.0039 17.4 0.0 0.0068 16.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Zn_clus PF00172.18 CRK38995.1 - 8.7e-05 22.6 12.9 0.0014 18.7 3.0 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain RbpA PF13397.6 CRK38995.1 - 0.044 14.4 0.4 0.076 13.6 0.4 1.5 1 1 0 1 1 1 0 RNA polymerase-binding protein PDE8 PF08629.10 CRK38995.1 - 0.2 11.6 1.4 0.36 10.8 0.2 2.0 2 0 0 2 2 2 0 PDE8 phosphodiesterase Mon1 PF03164.14 CRK39012.1 - 2.5e-11 43.3 0.1 3.1e-11 43.0 0.1 1.1 1 0 0 1 1 1 1 Trafficking protein Mon1 Exo_endo_phos_2 PF14529.6 CRK39012.1 - 0.031 14.1 0.0 0.056 13.3 0.0 1.4 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase Herpes_capsid PF06112.11 CRK39012.1 - 0.67 10.0 5.7 1.2 9.2 5.7 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Dopey_N PF04118.14 CRK39013.1 - 6.2e-91 304.7 0.0 9.6e-91 304.1 0.0 1.2 1 0 0 1 1 1 1 Dopey, N-terminal Methyltransf_15 PF09445.10 CRK39014.1 - 6.9e-21 74.5 0.0 8e-21 74.3 0.0 1.0 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MazG PF03819.17 CRK39015.1 - 0.04 14.1 0.0 0.089 13.0 0.0 1.6 2 0 0 2 2 2 0 MazG nucleotide pyrophosphohydrolase domain AdenylateSensor PF16579.5 CRK39020.1 - 3.4e-12 46.9 0.0 4.1e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 Adenylate sensor of SNF1-like protein kinase KA1 PF02149.19 CRK39020.1 - 0.05 13.4 0.1 12 5.7 0.0 2.2 2 0 0 2 2 2 0 Kinase associated domain 1 PNGaseA PF12222.8 CRK39021.1 - 1.1e-162 541.8 0.1 1.5e-162 541.4 0.1 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A TFIIA PF03153.13 CRK39041.1 - 1.6e-95 321.6 28.4 1.9e-95 321.3 28.4 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF1876 PF08962.11 CRK39041.1 - 0.066 13.2 2.4 7.2 6.6 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1876) tRNA-synt_2b PF00587.25 CRK39043.1 - 5.5e-39 134.0 0.0 1.9e-30 106.2 0.0 3.2 2 1 1 3 3 3 3 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 CRK39043.1 - 1.8e-13 50.5 0.0 9.3e-10 38.5 0.0 2.5 2 0 0 2 2 2 2 Anticodon binding domain 3HBOH PF10605.9 CRK39043.1 - 0.11 10.7 0.7 8 4.6 0.1 2.1 2 0 0 2 2 2 0 3HB-oligomer hydrolase (3HBOH) PGM1_C PF18105.1 CRK39043.1 - 0.17 11.4 3.5 10 5.7 0.3 2.8 2 0 0 2 2 2 0 PGM1 C-terminal domain Podoplanin PF05808.11 CRK39043.1 - 0.71 10.0 1.7 13 5.9 0.1 2.7 2 1 1 3 3 3 0 Podoplanin zf-C2H2_aberr PF17017.5 CRK39069.1 - 6.8e-06 26.3 1.5 0.013 15.7 0.3 2.4 2 0 0 2 2 2 2 Aberrant zinc-finger zf-C2H2 PF00096.26 CRK39069.1 - 0.00013 22.3 10.0 0.063 13.8 0.7 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CRK39069.1 - 0.0012 19.5 12.3 0.1 13.5 0.6 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CRK39069.1 - 0.02 15.3 13.3 0.074 13.5 0.5 3.3 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2_jaz PF12171.8 CRK39069.1 - 0.062 13.6 1.6 4.5 7.7 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Kelch_4 PF13418.6 CRK39071.1 - 1.1e-27 95.7 11.4 6.3e-08 32.5 0.0 5.4 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 CRK39071.1 - 1e-23 82.8 6.9 5.9e-06 26.1 0.0 4.9 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 CRK39071.1 - 8e-22 76.7 2.7 0.00032 20.9 0.0 5.2 4 1 1 5 5 5 4 Kelch motif Kelch_3 PF13415.6 CRK39071.1 - 1.3e-19 69.9 7.7 2.1e-07 31.1 0.1 5.7 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_1 PF01344.25 CRK39071.1 - 9.1e-19 66.8 1.3 0.00011 21.6 0.0 5.1 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.15 CRK39071.1 - 1.1e-17 63.2 4.6 7e-05 22.6 0.0 5.2 5 0 0 5 5 5 4 Kelch motif BTB PF00651.31 CRK39071.1 - 6.6e-09 36.0 0.0 1.1e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 CRK39071.1 - 0.12 12.5 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 BTB And C-terminal Kelch Myb_DNA-binding PF00249.31 CRK39072.1 - 0.047 13.9 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain Septin PF00735.18 CRK39075.1 - 9.9e-14 51.3 0.0 1.1e-13 51.1 0.0 1.0 1 0 0 1 1 1 1 Septin DUF89 PF01937.19 CRK39075.1 - 0.082 11.9 0.1 0.084 11.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF89 p450 PF00067.22 CRK39096.1 - 7.6e-39 133.7 0.0 1.2e-38 133.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.19 CRK39096.1 - 1.1e-18 67.7 2.9 1.2e-17 64.2 2.9 2.5 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 CRK39096.1 - 5.5e-05 22.4 0.0 0.00011 21.5 0.0 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein Amino_oxidase PF01593.24 CRK39096.1 - 0.00023 20.6 0.2 0.32 10.2 0.1 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CRK39096.1 - 0.0014 18.8 0.1 0.0039 17.4 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CRK39096.1 - 0.0016 18.1 0.0 0.0028 17.3 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 CRK39096.1 - 0.0016 19.0 0.1 0.01 16.4 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CRK39096.1 - 0.0037 16.6 0.0 0.0082 15.4 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CRK39096.1 - 0.023 13.9 0.1 0.094 11.9 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CRK39096.1 - 0.042 12.9 0.1 0.076 12.1 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain Acetyltransf_1 PF00583.25 CRK39099.1 - 0.0005 20.3 0.0 0.0013 19.0 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CRK39099.1 - 0.11 13.0 0.0 0.21 12.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Gemini_C4 PF01492.17 CRK39099.1 - 0.15 12.0 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Geminivirus C4 protein zinc_ribbon_10 PF10058.9 CRK39100.1 - 5.1e-19 67.8 0.1 9.2e-19 66.9 0.1 1.5 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein Laminin_I PF06008.14 CRK39100.1 - 0.0052 16.5 8.4 0.0052 16.5 8.4 2.0 2 0 0 2 2 2 1 Laminin Domain I DUF3611 PF12263.8 CRK39100.1 - 0.049 13.5 0.2 0.08 12.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) NPV_P10 PF05531.12 CRK39100.1 - 0.13 12.7 0.8 1.1 9.8 0.9 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF745 PF05335.13 CRK39100.1 - 0.33 10.6 12.1 0.053 13.2 7.2 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF745) THOC7 PF05615.13 CRK39100.1 - 0.44 10.8 20.6 1.7 8.9 11.1 3.1 3 0 0 3 3 3 0 Tho complex subunit 7 SKA1 PF07160.12 CRK39100.1 - 1.2 8.9 11.6 1.1 9.1 3.1 2.7 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 1 Lectin_N PF03954.14 CRK39100.1 - 2.5 7.9 6.7 23 4.7 2.9 3.0 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain Ima1_N PF09779.9 CRK39100.1 - 5.4 7.9 9.9 1.5 9.7 2.9 3.1 2 1 1 3 3 3 0 Ima1 N-terminal domain DUF1664 PF07889.12 CRK39100.1 - 6 6.9 8.3 2.3 8.3 2.0 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) DUF4200 PF13863.6 CRK39100.1 - 7.7 6.9 27.5 0.29 11.5 16.1 2.7 3 0 0 3 3 2 0 Domain of unknown function (DUF4200) TPR_16 PF13432.6 CRK39119.1 - 2.1e-05 25.1 15.3 0.0062 17.2 7.7 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 CRK39119.1 - 0.00078 19.9 6.5 0.077 13.5 0.4 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 CRK39119.1 - 0.0033 17.4 10.6 0.14 12.3 0.3 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 CRK39119.1 - 0.027 14.8 12.6 0.096 13.0 5.0 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 CRK39119.1 - 0.27 11.1 0.1 0.27 11.1 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat SQHop_cyclase_C PF13243.6 CRK39121.1 - 6e-32 111.0 0.6 4.7e-31 108.1 0.8 2.1 3 0 0 3 3 3 1 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 CRK39121.1 - 1.5e-27 96.5 3.6 6.4e-23 81.3 0.2 3.5 1 1 1 3 3 3 3 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 CRK39121.1 - 1.1e-22 79.4 18.8 3.1e-08 33.2 1.0 4.8 4 1 0 4 4 4 4 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 CRK39121.1 - 0.0038 16.3 1.1 2.8 6.9 0.0 2.8 1 1 2 3 3 3 2 A-macroglobulin TED domain TP6A_N PF04406.14 CRK39123.1 - 8.4e-18 64.1 0.0 1.4e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 Type IIB DNA topoisomerase DUF2399 PF09664.10 CRK39123.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2399) Ank_4 PF13637.6 CRK39125.1 - 8.5e-07 29.4 0.4 2.1e-06 28.2 0.4 1.7 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 CRK39125.1 - 1.1e-06 28.8 1.4 0.0061 16.8 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CRK39125.1 - 1.3e-06 28.8 1.0 2.7e-06 27.9 1.0 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CRK39125.1 - 1.6e-06 28.0 1.0 0.0059 17.0 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 CRK39125.1 - 3e-05 24.3 2.0 0.049 14.1 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeat DUF2336 PF10098.9 CRK39125.1 - 0.014 14.9 4.2 0.027 14.0 4.2 1.4 1 1 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2336) Phe_tRNA-synt_N PF02912.18 CRK39125.1 - 0.092 12.7 0.0 0.59 10.1 0.0 1.9 2 0 0 2 2 2 0 Aminoacyl tRNA synthetase class II, N-terminal domain Elongin_A PF06881.11 CRK39153.1 - 6.2e-23 81.3 1.9 1.5e-22 80.1 1.9 1.6 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A TFIIF_beta_N PF17683.1 CRK39155.1 - 2.1e-27 96.4 0.0 4.7e-27 95.3 0.0 1.6 2 0 0 2 2 2 1 TFIIF, beta subunit N-terminus TFIIF_beta PF02270.15 CRK39155.1 - 1.7e-22 79.3 0.3 3.1e-22 78.5 0.3 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain DUF3591 PF12157.8 CRK39155.1 - 0.00036 19.3 0.2 0.00055 18.7 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) PTPA PF03095.15 CRK39159.1 - 1.1e-110 369.9 0.0 1.2e-110 369.7 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Aldedh PF00171.22 CRK39166.1 - 9.2e-08 31.0 0.0 9.2e-08 31.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Kelch_4 PF13418.6 CRK39184.1 - 6.5e-32 109.3 6.3 1.4e-06 28.2 0.0 6.5 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_1 PF01344.25 CRK39184.1 - 2.2e-29 100.8 4.2 2.1e-12 46.4 0.4 6.3 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 CRK39184.1 - 2.6e-29 100.5 2.7 8.2e-10 38.6 0.6 6.6 5 1 1 6 6 6 5 Kelch motif Kelch_5 PF13854.6 CRK39184.1 - 2.5e-28 97.5 6.8 1.1e-07 31.7 0.4 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 CRK39184.1 - 1.7e-26 91.9 14.0 1.2e-06 28.6 0.1 6.4 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.15 CRK39184.1 - 3.9e-18 64.7 9.1 1.2e-06 28.3 0.3 6.7 6 1 0 6 6 6 4 Kelch motif DUF4370 PF14290.6 CRK39184.1 - 0.17 11.7 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4370) DUF1518 PF07469.12 CRK39185.1 - 7.2 7.1 9.5 5.4 7.5 4.7 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1518) MIOX PF05153.15 CRK39186.1 - 6e-14 52.2 0.1 7.3e-14 51.9 0.1 1.1 1 0 0 1 1 1 1 Myo-inositol oxygenase DAD PF02109.16 CRK39187.1 - 0.063 13.6 0.1 0.063 13.6 0.1 1.2 1 0 0 1 1 1 0 DAD family Syntaxin PF00804.25 CRK39188.1 - 0.0014 18.4 1.8 0.0016 18.2 1.8 1.1 1 0 0 1 1 1 1 Syntaxin JIP_LZII PF16471.5 CRK39188.1 - 0.052 13.7 0.6 0.17 12.1 0.1 1.8 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II Allexi_40kDa PF05549.11 CRK39188.1 - 0.087 12.3 1.7 0.087 12.3 1.7 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein DASH_Dad3 PF08656.10 CRK39188.1 - 0.13 12.4 1.2 0.3 11.2 1.2 1.6 1 1 0 1 1 1 0 DASH complex subunit Dad3 Not3 PF04065.15 CRK39188.1 - 0.14 11.6 2.8 0.14 11.6 2.8 1.0 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component DASH_Dam1 PF08653.10 CRK39188.1 - 0.14 12.0 0.1 0.24 11.2 0.1 1.4 1 0 0 1 1 1 0 DASH complex subunit Dam1 DivIC PF04977.15 CRK39188.1 - 1.2 9.0 6.3 3.7 7.4 0.8 2.3 1 1 1 2 2 2 0 Septum formation initiator TMEM132D_C PF15706.5 CRK39190.1 - 4.3 7.2 7.2 4.2 7.2 0.4 2.7 2 1 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Acyl_transf_3 PF01757.22 CRK39191.1 - 3e-23 82.4 23.5 1.2e-22 80.4 23.5 1.8 1 1 0 1 1 1 1 Acyltransferase family GFA PF04828.14 CRK39191.1 - 9.4e-12 45.1 2.2 3.7e-11 43.2 2.2 2.1 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DUF1295 PF06966.12 CRK39192.1 - 3.2e-56 190.5 0.3 4.1e-56 190.1 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 CRK39192.1 - 2.3e-06 27.7 0.4 2.3e-06 27.7 0.4 2.9 2 1 2 4 4 4 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 CRK39192.1 - 0.00048 20.5 0.0 0.00048 20.5 0.0 2.5 3 1 0 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 CRK39192.1 - 0.0074 16.7 2.2 0.01 16.2 0.0 2.4 2 1 0 2 2 2 1 Phospholipid methyltransferase Ctf8 PF09696.10 CRK39193.1 - 3.5e-13 50.1 0.2 5.5e-13 49.5 0.2 1.4 1 1 0 1 1 1 1 Ctf8 MIR PF02815.19 CRK39194.1 - 1.7e-16 60.6 0.1 1.8e-16 60.5 0.1 1.0 1 0 0 1 1 1 1 MIR domain ArgoN PF16486.5 CRK39196.1 - 1.7e-17 64.3 0.0 2.9e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 CRK39196.1 - 9.9e-15 54.0 0.1 1.8e-14 53.1 0.1 1.5 1 0 0 1 1 1 1 Argonaute linker 1 domain PAZ PF02170.22 CRK39196.1 - 8.6e-06 25.6 0.0 1.4e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 PAZ domain ArgoL2 PF16488.5 CRK39196.1 - 0.0022 18.3 0.0 0.098 13.0 0.0 2.5 2 0 0 2 2 2 1 Argonaute linker 2 domain p450 PF00067.22 CRK39197.1 - 3.7e-38 131.5 0.0 2.8e-26 92.3 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 SMC_N PF02463.19 CRK39197.1 - 2.1e-37 128.7 0.4 4.7e-37 127.6 0.4 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CRK39197.1 - 6.6e-10 39.8 1.1 2.2e-09 38.1 1.2 1.9 2 1 0 2 2 2 1 AAA domain AAA_15 PF13175.6 CRK39197.1 - 9.6e-08 32.1 1.1 1.5e-07 31.5 1.1 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 CRK39197.1 - 3.9e-06 26.9 0.2 1.6e-05 24.9 0.2 2.1 1 1 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CRK39197.1 - 0.00025 20.7 0.0 0.0005 19.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Pkip-1 PF06878.11 CRK39197.1 - 0.069 13.3 1.6 0.14 12.3 1.6 1.5 1 0 0 1 1 1 0 Pkip-1 protein Taxilin PF09728.9 CRK39197.1 - 0.45 9.6 7.5 0.74 8.9 7.5 1.3 1 0 0 1 1 1 0 Myosin-like coiled-coil protein Jnk-SapK_ap_N PF09744.9 CRK39197.1 - 3.7 7.8 10.6 2.8 8.1 0.9 2.9 2 1 0 3 3 3 0 JNK_SAPK-associated protein-1 dCMP_cyt_deam_1 PF00383.23 CRK39198.1 - 2.4e-06 27.3 0.0 3e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CRK39198.1 - 5.3e-06 26.2 0.0 6.6e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase OTT_1508_deam PF14441.6 CRK39198.1 - 0.049 13.6 0.2 0.076 13.0 0.2 1.3 1 0 0 1 1 1 0 OTT_1508-like deaminase ELYS PF13934.6 CRK39200.1 - 1.7e-67 227.6 1.7 2.1e-67 227.3 1.7 1.1 1 0 0 1 1 1 1 Nuclear pore complex assembly SMC_N PF02463.19 CRK39202.1 - 1.3e-108 361.6 28.0 5.8e-74 248.2 9.8 3.6 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CRK39202.1 - 1.4e-44 151.2 0.0 6.3e-21 74.9 0.0 3.5 2 0 0 2 2 2 2 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 CRK39202.1 - 1.5e-18 67.7 0.1 6.3e-05 22.9 0.0 3.9 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system Tektin PF03148.14 CRK39202.1 - 1.8e-05 23.7 38.9 0.00012 21.0 15.5 9.0 6 3 4 10 10 8 2 Tektin family AAA_29 PF13555.6 CRK39202.1 - 0.0011 18.7 0.0 0.0021 17.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATG16 PF08614.11 CRK39202.1 - 0.0044 17.3 16.3 0.0044 17.3 16.3 12.3 6 3 3 10 10 10 3 Autophagy protein 16 (ATG16) Asp23 PF03780.13 CRK39202.1 - 0.0089 16.4 0.0 17 5.9 0.0 3.6 2 0 0 2 2 2 0 Asp23 family, cell envelope-related function Peptidase_U40 PF10464.9 CRK39202.1 - 0.029 14.1 2.8 5.7 6.5 0.2 2.9 2 0 0 2 2 2 0 Peptidase U40 AAA_22 PF13401.6 CRK39202.1 - 0.044 14.1 0.0 48 4.2 0.0 4.3 3 0 0 3 3 3 0 AAA domain ParE_toxin PF05016.15 CRK39202.1 - 0.13 12.9 17.8 0.55 10.9 0.7 4.8 4 0 0 4 4 4 0 ParE toxin of type II toxin-antitoxin system, parDE COMP PF11598.8 CRK39202.1 - 3.5 8.2 7.9 30 5.2 1.0 3.1 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein DASH_Dam1 PF08653.10 CRK39202.1 - 3.9 7.3 9.3 99 2.9 0.1 5.6 4 0 0 4 4 4 0 DASH complex subunit Dam1 SOG2 PF10428.9 CRK39204.1 - 0.13 11.4 13.7 0.18 11.0 13.7 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Ribosomal_S26e PF01283.19 CRK39206.1 - 9.7e-47 157.9 10.0 1.6e-22 80.0 0.1 2.0 2 0 0 2 2 2 2 Ribosomal protein S26e zf_CopZ PF18423.1 CRK39206.1 - 0.056 13.4 1.9 0.078 12.9 0.1 2.0 2 0 0 2 2 2 0 Zinc binding domain DUF4668 PF15701.5 CRK39206.1 - 0.095 12.5 0.6 0.17 11.7 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4668) Ribosomal_S27 PF01599.19 CRK39209.1 - 9.6e-27 92.9 1.2 9.6e-27 92.9 1.2 1.9 2 0 0 2 2 2 1 Ribosomal protein S27a ubiquitin PF00240.23 CRK39209.1 - 3.2e-16 58.8 0.4 7.7e-16 57.6 0.2 1.8 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 CRK39209.1 - 2.9e-06 27.0 0.1 7.1e-06 25.8 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CRK39209.1 - 0.001 19.5 0.1 0.0018 18.7 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain IBR PF01485.21 CRK39209.1 - 0.02 15.1 0.3 0.031 14.5 0.3 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Plexin_cytopl PF08337.12 CRK39209.1 - 0.031 12.9 0.1 0.033 12.9 0.1 1.0 1 0 0 1 1 1 0 Plexin cytoplasmic RasGAP domain Glyco_hydro_18 PF00704.28 CRK39210.1 - 1.1e-80 271.7 0.0 1.3e-80 271.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Cellulase PF00150.18 CRK39215.1 - 4e-21 75.7 0.0 8.4e-20 71.3 0.0 2.2 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) E1-E2_ATPase PF00122.20 CRK39217.1 - 1.7e-37 128.7 14.0 1.9e-30 105.7 0.1 3.6 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 CRK39217.1 - 1e-24 87.3 5.6 1e-24 87.3 5.6 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Sugar_tr PF00083.24 CRK39217.1 - 3.7e-20 72.2 11.6 2.4e-12 46.5 0.0 3.3 3 0 0 3 3 3 2 Sugar (and other) transporter Cation_ATPase PF13246.6 CRK39217.1 - 1e-19 70.4 0.0 2.3e-19 69.3 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CRK39217.1 - 1.7e-19 71.0 0.0 3.5e-16 60.1 0.0 2.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CRK39217.1 - 3.2e-16 58.8 1.4 5.3e-16 58.1 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus MFS_1 PF07690.16 CRK39217.1 - 7.4e-05 21.8 0.5 7.4e-05 21.8 0.5 5.0 5 1 0 5 5 5 1 Major Facilitator Superfamily Hydrolase_3 PF08282.12 CRK39217.1 - 0.00078 19.3 0.1 0.0039 17.0 0.2 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Gate PF07670.14 CRK39217.1 - 4.2 7.7 8.7 3.7 7.8 0.0 3.4 3 0 0 3 3 3 0 Nucleoside recognition DUF1993 PF09351.10 CRK39220.1 - 2.7e-48 164.1 1.7 5e-48 163.3 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1993) Sod_Fe_N PF00081.22 CRK39220.1 - 4e-32 110.5 1.3 4e-32 110.5 1.3 1.9 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sod_Fe_C PF02777.18 CRK39220.1 - 3.3e-31 107.5 0.0 6.5e-31 106.5 0.0 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain DUF1993 PF09351.10 CRK39222.1 - 2e-19 70.3 0.1 2.4e-19 70.1 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) Mto2_bdg PF12808.7 CRK39223.1 - 4.9e-14 52.4 18.7 3.6e-13 49.6 9.4 4.0 4 0 0 4 4 4 1 Micro-tubular organiser Mto1 C-term Mto2-binding region NPV_P10 PF05531.12 CRK39223.1 - 0.023 15.1 0.0 0.046 14.2 0.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein FtsL PF04999.13 CRK39223.1 - 0.094 12.7 0.1 0.28 11.2 0.1 1.8 2 0 0 2 2 2 0 Cell division protein FtsL Mto2_bdg PF12808.7 CRK39225.1 - 2e-12 47.2 9.4 2e-12 47.2 9.4 10.5 12 1 0 12 12 12 1 Micro-tubular organiser Mto1 C-term Mto2-binding region TetR_C_25 PF17933.1 CRK39225.1 - 0.0031 17.8 1.2 5.7 7.3 0.1 3.4 2 0 0 2 2 2 2 Tetracyclin repressor-like, C-terminal domain NPV_P10 PF05531.12 CRK39225.1 - 0.0032 17.9 24.7 0.28 11.7 0.0 6.9 4 1 1 5 5 5 2 Nucleopolyhedrovirus P10 protein ERM PF00769.19 CRK39225.1 - 0.0045 16.8 39.2 0.0045 16.8 39.2 5.2 4 1 4 8 8 8 2 Ezrin/radixin/moesin family TPR_MLP1_2 PF07926.12 CRK39225.1 - 0.0064 16.5 20.0 0.0064 16.5 20.0 6.0 4 1 3 7 7 6 2 TPR/MLP1/MLP2-like protein ATG16 PF08614.11 CRK39225.1 - 0.01 16.1 11.2 0.01 16.1 11.2 8.1 3 2 4 8 8 8 0 Autophagy protein 16 (ATG16) CHIPS PF11434.8 CRK39225.1 - 0.11 12.4 0.3 28 4.6 0.0 2.8 2 0 0 2 2 2 0 Chemotaxis-inhibiting protein CHIPS FtsL PF04999.13 CRK39225.1 - 0.28 11.2 14.9 1.5 8.8 0.1 5.2 4 1 1 5 5 5 0 Cell division protein FtsL EzrA PF06160.12 CRK39225.1 - 0.33 9.1 59.0 0.019 13.2 30.4 3.4 1 1 2 3 3 3 0 Septation ring formation regulator, EzrA Fib_alpha PF08702.10 CRK39225.1 - 0.42 10.8 52.6 0.71 10.1 7.2 6.7 3 1 5 8 8 8 0 Fibrinogen alpha/beta chain family AAA_13 PF13166.6 CRK39225.1 - 0.78 8.3 54.4 0.28 9.8 30.8 3.3 2 1 2 4 4 4 0 AAA domain Baculo_PEP_C PF04513.12 CRK39225.1 - 1.3 9.0 37.3 0.69 9.9 6.5 6.4 4 1 3 7 7 7 0 Baculovirus polyhedron envelope protein, PEP, C terminus GP41 PF00517.17 CRK39225.1 - 2 8.3 12.3 29 4.5 0.0 5.1 4 2 1 5 5 5 0 Retroviral envelope protein DUF1664 PF07889.12 CRK39225.1 - 2.6 8.1 50.3 3.3 7.8 3.2 7.2 3 1 2 7 7 7 0 Protein of unknown function (DUF1664) DUF2935 PF11155.8 CRK39225.1 - 4.5 7.6 14.9 1.8 8.9 1.4 4.1 3 2 1 4 4 4 0 Domain of unknown function (DUF2935) FAD-oxidase_C PF02913.19 CRK39227.1 - 8.9e-30 104.1 0.2 9.6e-30 104.0 0.2 1.0 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain GATA PF00320.27 CRK39230.1 - 5.6e-16 57.9 5.4 9.9e-16 57.1 5.4 1.4 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.12 CRK39230.1 - 1.6e-11 44.3 0.0 3.3e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 CRK39230.1 - 9.7e-08 32.0 0.0 2.5e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 CRK39230.1 - 0.00032 20.9 0.2 0.0011 19.1 0.0 2.0 2 0 0 2 2 2 1 PAS domain PAS_11 PF14598.6 CRK39230.1 - 0.00084 19.4 0.0 0.0015 18.6 0.0 1.4 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 CRK39230.1 - 0.0082 16.4 0.0 0.017 15.4 0.0 1.5 1 0 0 1 1 1 1 PAS fold Zn-ribbon_8 PF09723.10 CRK39230.1 - 0.0095 16.0 0.2 0.02 15.0 0.2 1.5 1 0 0 1 1 1 1 Zinc ribbon domain TF_Zn_Ribbon PF08271.12 CRK39230.1 - 0.11 12.0 0.6 0.71 9.4 0.1 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding AAA_23 PF13476.6 CRK39232.1 - 6.3e-32 111.7 0.0 6.3e-32 111.7 0.0 7.6 2 1 2 4 4 3 1 AAA domain AAA_21 PF13304.6 CRK39232.1 - 9e-11 42.1 8.2 8e-05 22.6 0.0 4.8 3 2 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 CRK39232.1 - 6.7e-07 29.4 0.0 3.6e-06 27.1 0.0 2.4 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.19 CRK39232.1 - 2.2e-06 27.3 0.1 2.2e-06 27.3 0.1 2.8 2 1 0 2 2 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CRK39232.1 - 0.0016 18.1 0.0 0.0036 17.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Strep_SA_rep PF06696.11 CRK39232.1 - 0.016 15.2 1.0 4.1 7.5 0.3 3.4 2 0 0 2 2 2 0 Streptococcal surface antigen repeat AAA_13 PF13166.6 CRK39232.1 - 0.024 13.3 0.0 0.024 13.3 0.0 7.6 1 1 3 7 7 7 0 AAA domain AAA_16 PF13191.6 CRK39232.1 - 0.072 13.5 0.1 0.072 13.5 0.1 4.8 4 2 2 6 6 6 0 AAA ATPase domain ABC_tran PF00005.27 CRK39232.1 - 0.11 13.0 0.1 0.11 13.0 0.1 6.4 2 1 0 4 4 2 0 ABC transporter cobW PF02492.19 CRK39232.1 - 0.14 11.7 4.8 0.56 9.8 0.0 3.1 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 CRK39232.1 - 0.76 9.8 6.8 7.8 6.5 0.1 3.8 5 0 0 5 5 5 0 AAA domain (dynein-related subfamily) DUF4172 PF13776.6 CRK39232.1 - 7.6 6.9 11.8 18 5.7 0.1 5.2 5 1 0 5 5 5 0 Domain of unknown function (DUF4172) PPP4R2 PF09184.11 CRK39234.1 - 5.8e-09 35.9 4.7 5.8e-09 35.9 4.7 3.4 2 1 1 3 3 3 1 PPP4R2 Herpes_UL17 PF04559.12 CRK39234.1 - 8.8 5.0 7.7 15 4.2 7.7 1.3 1 0 0 1 1 1 0 Herpesvirus UL17 protein Aldedh PF00171.22 CRK39236.1 - 3.2e-154 513.9 2.9 1.6e-152 508.3 2.9 2.0 1 1 0 1 1 1 1 Aldehyde dehydrogenase family Glyco_hydro_79C PF16862.5 CRK39238.1 - 1e-23 84.2 0.0 2.3e-23 83.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain DUF2371 PF10177.9 CRK39240.1 - 0.031 14.5 0.0 0.069 13.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) FAM176 PF14851.6 CRK39240.1 - 0.16 11.6 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 FAM176 family EI24 PF07264.11 CRK39240.1 - 0.22 11.8 6.7 0.54 10.5 7.0 1.5 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) DUF2615 PF11027.8 CRK39240.1 - 0.22 11.7 0.5 10 6.3 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2615) Amidase PF01425.21 CRK39242.1 - 7e-65 219.7 0.1 2.8e-64 217.7 0.1 1.8 1 1 0 1 1 1 1 Amidase GATA PF00320.27 CRK39244.1 - 6e-16 57.8 5.4 1.1e-15 57.0 5.4 1.4 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.12 CRK39244.1 - 1.7e-11 44.2 0.0 3.5e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 CRK39244.1 - 1e-07 31.9 0.1 2.7e-07 30.6 0.0 1.7 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 CRK39244.1 - 0.00036 20.7 0.2 0.0012 19.0 0.0 2.0 2 0 0 2 2 2 1 PAS domain PAS_11 PF14598.6 CRK39244.1 - 0.00092 19.3 0.0 0.0017 18.5 0.0 1.3 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 CRK39244.1 - 0.0089 16.3 0.0 0.018 15.3 0.0 1.5 1 0 0 1 1 1 1 PAS fold Zn-ribbon_8 PF09723.10 CRK39244.1 - 0.01 15.9 0.2 0.021 14.9 0.2 1.5 1 0 0 1 1 1 0 Zinc ribbon domain TF_Zn_Ribbon PF08271.12 CRK39244.1 - 0.13 11.8 0.7 0.78 9.3 0.1 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding AAA_23 PF13476.6 CRK39247.1 - 6.5e-32 111.7 0.0 6.5e-32 111.7 0.0 7.7 2 1 4 6 6 6 1 AAA domain AAA_21 PF13304.6 CRK39247.1 - 2.1e-10 40.9 6.9 7.9e-05 22.6 0.0 4.2 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 CRK39247.1 - 7.7e-07 29.3 0.0 3.7e-06 27.1 0.0 2.3 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.19 CRK39247.1 - 2.3e-06 27.2 0.1 2.3e-06 27.2 0.1 3.1 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CRK39247.1 - 0.0017 18.1 0.0 0.0037 17.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain cobW PF02492.19 CRK39247.1 - 0.0057 16.3 0.4 0.57 9.7 0.0 3.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_13 PF13166.6 CRK39247.1 - 0.024 13.3 0.0 0.024 13.3 0.0 7.0 1 1 3 6 6 6 0 AAA domain AAA_16 PF13191.6 CRK39247.1 - 0.074 13.4 0.1 0.074 13.4 0.1 4.6 4 2 0 4 4 4 0 AAA ATPase domain ABC_tran PF00005.27 CRK39247.1 - 0.12 12.9 0.1 0.12 12.9 0.1 6.7 2 1 0 4 4 4 0 ABC transporter AAA_5 PF07728.14 CRK39247.1 - 0.76 9.8 6.7 9.4 6.2 0.1 3.9 5 0 0 5 5 5 0 AAA domain (dynein-related subfamily) PPP4R2 PF09184.11 CRK39249.1 - 1.1e-09 38.3 3.7 1.1e-09 38.3 3.7 3.4 2 1 0 2 2 2 1 PPP4R2 Herpes_UL17 PF04559.12 CRK39249.1 - 2.4 6.9 8.2 3.4 6.4 8.2 1.3 1 0 0 1 1 1 0 Herpesvirus UL17 protein Aldedh PF00171.22 CRK39251.1 - 6.4e-171 568.9 0.2 7.3e-171 568.7 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Glyco_hydro_79C PF16862.5 CRK39253.1 - 2.6e-23 82.9 0.0 5.6e-23 81.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain DUF2371 PF10177.9 CRK39255.1 - 0.024 14.8 0.1 0.052 13.7 0.0 1.5 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) FAM176 PF14851.6 CRK39255.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 FAM176 family TMEM51 PF15345.6 CRK39255.1 - 0.22 11.3 0.0 0.32 10.8 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 EI24 PF07264.11 CRK39255.1 - 1 9.6 9.4 2.7 8.2 9.6 1.6 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) HATPase_c PF02518.26 CRK39257.1 - 1e-23 83.9 0.0 1.9e-23 83.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS PF00989.25 CRK39257.1 - 5.7e-18 65.0 1.0 5.9e-06 26.3 0.0 4.7 4 0 0 4 4 4 3 PAS fold PAS_4 PF08448.10 CRK39257.1 - 2.4e-14 53.5 0.0 0.00023 21.4 0.0 4.1 3 0 0 3 3 3 3 PAS fold GAF_3 PF13492.6 CRK39257.1 - 3e-13 50.2 0.1 0.02 15.3 0.0 3.7 3 0 0 3 3 3 3 GAF domain HisKA PF00512.25 CRK39257.1 - 6.5e-13 48.5 1.8 6.7e-07 29.3 0.1 4.3 5 0 0 5 5 5 2 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 CRK39257.1 - 7.3e-12 45.5 0.2 0.00097 19.4 0.0 4.2 4 1 1 5 5 5 2 PAS domain GAF_2 PF13185.6 CRK39257.1 - 2.7e-11 43.9 0.5 0.39 11.0 0.0 4.8 4 0 0 4 4 4 4 GAF domain PAS_8 PF13188.7 CRK39257.1 - 2.7e-10 40.0 0.0 0.1 12.6 0.0 4.3 4 0 0 4 4 4 3 PAS domain PAS_3 PF08447.12 CRK39257.1 - 1.1e-08 35.2 1.5 0.006 16.8 0.1 3.1 2 0 0 2 2 2 2 PAS fold GA-like PF17573.2 CRK39257.1 - 0.01 15.7 0.1 4.5 7.3 0.0 2.5 2 0 0 2 2 2 0 GA-like domain UNC-79 PF14776.6 CRK39257.1 - 0.29 9.8 6.1 3.7 6.2 0.2 2.6 3 0 0 3 3 3 0 Cation-channel complex subunit UNC-79 RRF PF01765.19 CRK39259.1 - 2.8e-22 79.4 0.4 3.2e-22 79.2 0.4 1.0 1 0 0 1 1 1 1 Ribosome recycling factor Response_reg PF00072.24 CRK39260.1 - 2.8e-21 75.8 0.1 4.2e-21 75.2 0.1 1.3 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 CRK39260.1 - 2.2e-16 60.4 0.2 3.7e-16 59.6 0.2 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HTH_24 PF13412.6 CRK39260.1 - 0.081 12.5 0.1 0.15 11.6 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding PH_6 PF15406.6 CRK39265.1 - 6.5e-47 158.4 1.5 6.5e-47 158.4 1.5 3.1 3 0 0 3 3 3 1 Pleckstrin homology domain PH PF00169.29 CRK39265.1 - 0.00031 21.2 0.0 0.00064 20.2 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_4 PF15404.6 CRK39265.1 - 0.18 11.6 0.0 0.42 10.4 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain MbeD_MobD PF04899.12 CRK39267.1 - 0.6 10.3 3.5 0.38 10.9 0.3 2.3 3 0 0 3 3 3 0 MbeD/MobD like tRNA-synt_2 PF00152.20 CRK39269.1 - 5.5e-60 203.1 0.0 7e-60 202.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.20 CRK39269.1 - 1e-05 25.1 0.0 0.0042 16.6 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) zf-Tim10_DDP PF02953.15 CRK39270.1 - 4e-17 61.6 2.9 4.7e-17 61.4 2.9 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF3556 PF12077.8 CRK39270.1 - 0.055 11.9 0.1 0.055 11.9 0.1 1.0 1 0 0 1 1 1 0 Transmembrane protein of unknown function (DUF3556) MFS_1 PF07690.16 CRK39272.1 - 1.5e-31 109.6 20.0 1.2e-23 83.7 0.5 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK39272.1 - 3.3e-13 49.3 0.0 3.3e-13 49.3 0.0 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter DUF819 PF05684.12 CRK39272.1 - 0.001 18.2 1.5 0.0079 15.3 0.2 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF819) Pkinase PF00069.25 CRK39275.1 - 5.8e-20 71.8 0.0 1.3e-13 51.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CRK39275.1 - 0.0013 18.1 0.3 0.066 12.5 0.0 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase ADH_zinc_N PF00107.26 CRK39277.1 - 3e-20 72.5 0.0 5.3e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 CRK39277.1 - 7.6e-18 64.4 0.0 2.1e-17 63.0 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 CRK39277.1 - 1.5e-06 29.3 0.0 3.5e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Erv26 PF04148.13 CRK39280.1 - 3.3e-89 298.2 3.3 3.8e-89 298.0 3.3 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 Cytochrom_C_asm PF01578.20 CRK39280.1 - 0.016 15.0 1.4 0.016 15.0 1.4 1.6 2 0 0 2 2 2 0 Cytochrome C assembly protein DUF3169 PF11368.8 CRK39280.1 - 0.38 10.2 4.8 0.26 10.8 2.8 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3169) Methyltransf_11 PF08241.12 CRK39281.1 - 2.6e-11 44.0 0.0 5.2e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK39281.1 - 7.4e-11 42.6 0.0 1.7e-10 41.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain WBS_methylT PF12589.8 CRK39281.1 - 7.9e-11 42.6 2.7 1.6e-10 41.6 2.7 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_12 PF08242.12 CRK39281.1 - 5.4e-05 23.9 0.0 0.0002 22.0 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 CRK39281.1 - 0.00059 19.7 0.0 0.001 18.9 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 CRK39281.1 - 0.0014 18.4 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CRK39281.1 - 0.01 15.7 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 CRK39281.1 - 0.014 14.7 0.0 0.14 11.5 0.0 2.0 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Methyltransf_33 PF10017.9 CRK39281.1 - 0.02 14.1 0.0 0.03 13.5 0.0 1.2 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Methyltransf_2 PF00891.18 CRK39281.1 - 0.038 13.3 0.0 0.074 12.3 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain HET PF06985.11 CRK39283.1 - 6.4e-29 101.2 0.2 1.1e-28 100.4 0.2 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SLT_L PF14718.6 CRK39283.1 - 0.027 14.6 1.5 0.057 13.6 1.5 1.5 1 0 0 1 1 1 0 Soluble lytic murein transglycosylase L domain ADC PF06314.11 CRK39285.1 - 0.00038 20.1 0.0 0.00065 19.3 0.0 1.3 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) MutS_V PF00488.21 CRK39286.1 - 3.4e-49 167.4 0.8 6.6e-49 166.5 0.8 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 CRK39286.1 - 6.9e-21 75.3 1.3 4.5e-19 69.4 1.3 2.3 1 1 0 1 1 1 1 MutS domain III MutS_II PF05188.17 CRK39286.1 - 6.6e-06 26.4 0.0 2e-05 24.9 0.0 1.9 2 0 0 2 2 2 1 MutS domain II DUF2093 PF09866.9 CRK39286.1 - 0.15 11.5 0.0 0.42 10.1 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2093) WD40 PF00400.32 CRK39289.1 - 9.7e-48 159.2 22.4 7.2e-09 36.1 0.1 7.8 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK39289.1 - 1.4e-15 57.3 4.0 0.0038 17.5 0.0 5.4 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 CRK39289.1 - 1.1e-05 25.9 0.0 2.2e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.8 CRK39289.1 - 0.00024 19.9 0.8 0.37 9.4 0.1 2.8 2 1 0 3 3 3 2 Nucleoporin Nup120/160 eIF2A PF08662.11 CRK39289.1 - 0.00035 20.5 0.1 0.006 16.5 0.0 2.8 2 2 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CRK39289.1 - 0.009 15.0 0.0 0.3 10.0 0.0 2.7 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 CRK39289.1 - 0.041 12.6 0.0 6.1 5.5 0.0 2.6 2 1 1 3 3 3 0 Nup133 N terminal like FAD_binding_9 PF08021.11 CRK39289.1 - 0.1 12.8 0.0 7.5 6.8 0.0 2.7 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain WD40_like PF17005.5 CRK39289.1 - 0.15 11.3 0.0 27 4.0 0.0 2.8 3 0 0 3 3 3 0 WD40-like domain Glyco_transf_20 PF00982.21 CRK39291.1 - 2.8e-252 837.5 0.3 5.6e-87 292.4 0.0 4.8 5 1 1 6 6 6 4 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 CRK39291.1 - 6.8e-90 300.3 0.0 5.1e-44 150.1 0.0 2.3 2 0 0 2 2 2 2 Trehalose-phosphatase WD40 PF00400.32 CRK39291.1 - 1.7e-46 155.3 27.7 1.9e-09 37.9 0.5 8.7 8 0 0 8 8 8 6 WD domain, G-beta repeat Aminotran_4 PF01063.19 CRK39291.1 - 3.1e-28 99.2 0.0 7.4e-24 84.8 0.0 2.4 2 0 0 2 2 2 2 Amino-transferase class IV ANAPC4_WD40 PF12894.7 CRK39291.1 - 1.1e-14 54.5 4.5 0.035 14.4 0.0 6.5 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 CRK39291.1 - 2.6e-05 24.7 0.1 6.1e-05 23.5 0.1 1.6 1 0 0 1 1 1 1 NLE (NUC135) domain eIF2A PF08662.11 CRK39291.1 - 0.00067 19.6 0.0 0.018 14.9 0.0 2.4 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 CRK39291.1 - 0.00082 18.1 2.4 1.5 7.4 0.1 3.3 2 1 0 3 3 3 2 Nucleoporin Nup120/160 HNOB PF07700.15 CRK39291.1 - 0.0011 18.9 0.1 2.3 8.1 0.0 2.4 2 0 0 2 2 2 2 Haem-NO-binding Glyco_transf_5 PF08323.11 CRK39291.1 - 0.0082 15.9 4.8 1.3 8.6 0.4 2.4 2 0 0 2 2 2 2 Starch synthase catalytic domain GYD PF08734.11 CRK39291.1 - 0.063 13.2 0.7 20 5.2 0.1 2.8 2 0 0 2 2 2 0 GYD domain Ge1_WD40 PF16529.5 CRK39291.1 - 0.15 11.0 0.2 2.4 7.0 0.1 2.8 2 2 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein MBA1 PF07961.11 CRK39291.1 - 0.17 10.9 0.2 19 4.2 0.0 2.2 2 0 0 2 2 2 0 MBA1-like protein DUF1043 PF06295.12 CRK39291.1 - 5.8 6.9 8.2 5.6 7.0 0.1 2.7 3 0 0 3 3 2 0 Protein of unknown function (DUF1043) Toxin_29 PF08116.11 CRK39295.1 - 0.29 11.2 1.2 0.72 9.9 1.2 1.6 1 0 0 1 1 1 0 PhTx neurotoxin family RSN1_TM PF13967.6 CRK39297.1 - 1.8e-37 128.5 0.9 1.8e-37 128.5 0.9 1.5 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 CRK39297.1 - 3.3e-13 50.2 0.0 5.1e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Lig_chan PF00060.26 CRK39297.1 - 5.3 6.9 6.0 5.1 6.9 0.2 2.5 3 0 0 3 3 3 0 Ligand-gated ion channel Toxin_29 PF08116.11 CRK39300.1 - 0.23 11.5 0.7 0.65 10.0 0.7 1.7 1 0 0 1 1 1 0 PhTx neurotoxin family RSN1_7TM PF02714.15 CRK39302.1 - 9.4e-73 244.9 21.6 1.7e-72 244.0 21.6 1.4 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 CRK39302.1 - 2.4e-37 128.9 0.0 3.5e-37 128.3 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 CRK39302.1 - 4e-36 124.1 0.4 4e-36 124.1 0.4 2.4 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport 2-Hacid_dh_C PF02826.19 CRK39304.1 - 1.5e-54 184.1 0.0 4.4e-54 182.5 0.0 1.9 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MFS_1 PF07690.16 CRK39304.1 - 1.9e-39 135.6 32.6 1.9e-39 135.6 32.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily 2-Hacid_dh PF00389.30 CRK39304.1 - 1.5e-26 92.6 0.0 2.5e-26 91.9 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain FMO-like PF00743.19 CRK39304.1 - 3e-15 55.7 0.0 1.3e-13 50.2 0.0 2.2 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 CRK39304.1 - 5.1e-11 42.3 1.6 5.1e-09 35.8 0.2 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CRK39304.1 - 3.5e-10 40.1 0.9 6.8e-09 35.9 0.3 2.7 2 1 0 2 2 2 1 FAD-NAD(P)-binding Sugar_tr PF00083.24 CRK39304.1 - 3.2e-07 29.6 20.1 8.3e-07 28.2 20.1 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter NAD_binding_8 PF13450.6 CRK39304.1 - 4.7e-07 29.9 1.0 1.6e-06 28.2 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 CRK39304.1 - 1e-06 28.2 0.0 1.1e-05 24.8 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 CRK39304.1 - 7.7e-06 25.4 2.6 0.011 15.1 0.0 3.6 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 CRK39304.1 - 1.6e-05 24.4 0.0 0.0084 15.4 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.24 CRK39304.1 - 0.00012 21.8 0.4 0.32 10.5 0.1 3.0 2 1 0 3 3 3 2 FAD dependent oxidoreductase TRI12 PF06609.13 CRK39304.1 - 0.00015 20.4 5.1 0.00023 19.7 5.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) NAD_binding_2 PF03446.15 CRK39304.1 - 0.00017 21.8 0.0 0.00039 20.6 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox PF00070.27 CRK39304.1 - 0.0017 18.9 4.7 12 6.5 0.4 3.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase IlvN PF07991.12 CRK39304.1 - 0.003 17.2 0.0 0.012 15.2 0.0 2.0 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Thi4 PF01946.17 CRK39304.1 - 0.0045 16.3 0.0 0.0079 15.5 0.0 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 CRK39304.1 - 0.0066 15.2 0.1 0.01 14.6 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 CRK39304.1 - 0.097 11.9 0.1 0.18 11.0 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain Peptidase_C12 PF01088.21 CRK39307.1 - 3.3e-47 161.0 0.0 5e-47 160.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 7tm_2 PF00002.24 CRK39307.1 - 1.9e-08 33.9 14.2 1.9e-08 33.9 14.2 1.7 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) Git3 PF11710.8 CRK39307.1 - 7.6e-06 25.8 13.7 1.2e-05 25.2 13.7 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Dicty_CAR PF05462.11 CRK39307.1 - 8.9e-06 25.0 12.0 1.7e-05 24.1 12.0 1.3 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor FixP_N PF14715.6 CRK39307.1 - 0.07 12.9 0.9 0.26 11.0 0.9 2.0 1 0 0 1 1 1 0 N-terminal domain of cytochrome oxidase-cbb3, FixP Binary_toxB PF03495.14 CRK39310.1 - 1 9.6 3.6 0.35 11.1 0.3 2.0 2 0 0 2 2 2 0 Clostridial binary toxin B/anthrax toxin PA Ca-binding domain CTP_transf_like PF01467.26 CRK39312.1 - 3.7e-20 72.6 0.0 4.5e-20 72.3 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like 4HBT PF03061.22 CRK39317.1 - 2.2e-06 27.9 0.0 5.2e-06 26.7 0.1 1.6 2 0 0 2 2 2 1 Thioesterase superfamily DUF3659 PF12396.8 CRK39317.1 - 0.11 12.4 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3659) C2 PF00168.30 CRK39320.1 - 2.5e-12 47.0 0.0 5.2e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 C2 domain DUF5525 PF17663.1 CRK39325.1 - 2.4 6.2 15.2 0.062 11.4 6.9 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5525) peroxidase PF00141.23 CRK39327.1 - 8.7e-86 287.3 0.0 6.3e-45 153.6 0.0 2.2 2 0 0 2 2 2 2 Peroxidase GST_C_3 PF14497.6 CRK39327.1 - 0.13 12.5 0.0 23 5.3 0.0 2.6 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Oxidored_molyb PF00174.19 CRK39332.1 - 2.4e-13 50.1 0.0 2.6e-13 50.0 0.0 1.0 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain HD_4 PF13328.6 CRK39334.1 - 0.07 12.9 0.1 0.079 12.7 0.1 1.1 1 0 0 1 1 1 0 HD domain FAD_binding_4 PF01565.23 CRK39336.1 - 3e-22 78.9 2.4 7.6e-22 77.5 2.4 1.8 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 CRK39336.1 - 1.1e-09 38.2 0.9 1.1e-09 38.2 0.9 1.8 2 0 0 2 2 2 1 Berberine and berberine like CFEM PF05730.11 CRK39338.1 - 4e-12 46.0 11.6 7.4e-12 45.2 11.6 1.4 1 0 0 1 1 1 1 CFEM domain Gamma-thionin PF00304.20 CRK39338.1 - 0.2 11.9 5.5 0.077 13.3 2.0 2.0 2 0 0 2 2 2 0 Gamma-thionin family YiaAB PF05360.14 CRK39338.1 - 1.6 9.0 12.5 0.23 11.7 2.1 3.9 3 1 0 3 3 3 0 yiaA/B two helix domain p450 PF00067.22 CRK39340.1 - 9e-57 192.8 0.0 2.1e-56 191.6 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 DUF3931 PF13082.6 CRK39340.1 - 0.11 12.7 0.1 0.24 11.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3931) Glyco_hydro_114 PF03537.13 CRK39342.1 - 1.6e-87 292.6 0.0 1.9e-87 292.4 0.0 1.0 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 Lactonase PF10282.9 CRK39343.1 - 1.6e-70 238.1 0.0 2.2e-70 237.6 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller ANAPC4_WD40 PF12894.7 CRK39343.1 - 0.18 12.2 0.0 11 6.4 0.0 3.0 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Aldo_ket_red PF00248.21 CRK39345.1 - 1.7e-67 227.7 0.0 2.1e-67 227.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family E1-E2_ATPase PF00122.20 CRK39351.1 - 1.4e-36 125.7 1.3 1.4e-36 125.7 1.3 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 CRK39351.1 - 1.2e-19 71.5 1.4 2.2e-19 70.6 0.6 1.9 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CRK39351.1 - 2.1e-14 52.9 0.0 4.6e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase_C PF00689.21 CRK39351.1 - 2.7e-13 50.0 9.0 2.7e-13 50.0 9.0 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 CRK39351.1 - 6.1e-06 26.2 0.0 1.2e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Glyco_transf_28 PF03033.20 CRK39351.1 - 0.0057 16.7 0.0 0.25 11.4 0.0 2.7 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain Hydrolase_3 PF08282.12 CRK39351.1 - 0.0072 16.1 0.2 0.028 14.2 0.2 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase EVE PF01878.18 CRK39354.1 - 6.8e-41 139.7 1.1 8e-41 139.4 0.0 1.6 2 0 0 2 2 2 1 EVE domain Ndc1_Nup PF09531.10 CRK39354.1 - 1.4 7.5 6.7 1.6 7.3 6.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup UL42 PF17638.2 CRK39354.1 - 3.7 7.5 7.3 8.8 6.3 7.3 1.7 1 0 0 1 1 1 0 HCMV UL42 CDC27 PF09507.10 CRK39354.1 - 8.5 5.6 19.8 12 5.2 19.8 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 QRPTase_C PF01729.19 CRK39355.1 - 3.8e-54 183.0 0.5 4.5e-54 182.7 0.5 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 CRK39355.1 - 9e-17 60.9 0.0 8.6e-16 57.8 0.0 2.4 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain Cu_amine_oxid PF01179.20 CRK39357.1 - 3.2e-149 497.3 0.0 3.9e-149 497.0 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 CRK39357.1 - 0.0022 18.2 0.1 0.015 15.5 0.0 2.2 2 0 0 2 2 2 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 CRK39357.1 - 0.078 13.4 0.0 0.27 11.7 0.0 1.9 2 0 0 2 2 2 0 Copper amine oxidase, N3 domain AMP-binding PF00501.28 CRK39359.1 - 9.7e-85 284.7 0.0 1.3e-84 284.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CRK39359.1 - 1.2e-19 71.1 0.1 4.4e-19 69.2 0.1 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Gly_transf_sug PF04488.15 CRK39359.1 - 6.6e-14 52.3 0.0 1.4e-13 51.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Zn_clus PF00172.18 CRK39361.1 - 0.024 14.7 2.3 0.048 13.8 2.3 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PAF-AH_p_II PF03403.13 CRK39363.1 - 3.7e-17 61.9 0.0 6.2e-08 31.5 0.0 2.5 1 1 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Hydrolase_4 PF12146.8 CRK39363.1 - 3.2e-06 26.6 0.0 0.037 13.3 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 CRK39363.1 - 5.8e-06 25.4 0.0 1.1e-05 24.5 0.0 1.4 2 0 0 2 2 2 1 Chlorophyllase enzyme Abhydrolase_6 PF12697.7 CRK39363.1 - 0.00017 22.3 5.0 0.00017 22.3 5.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 CRK39363.1 - 0.018 14.8 0.1 4.1 7.2 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CRK39363.1 - 0.029 14.0 0.8 1.6 8.3 0.1 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold RPE65 PF03055.15 CRK39365.1 - 1.6e-16 60.6 0.0 1.8e-16 60.4 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein DUF3215 PF11503.8 CRK39367.1 - 0.0087 15.9 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3215) EVE PF01878.18 CRK39369.1 - 1.7e-41 141.6 1.0 2.2e-41 141.3 0.0 1.6 2 0 0 2 2 2 1 EVE domain QRPTase_C PF01729.19 CRK39371.1 - 5.3e-54 182.5 0.5 6.4e-54 182.2 0.5 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 CRK39371.1 - 1.4e-16 60.3 0.0 1.1e-15 57.4 0.0 2.4 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain Cu_amine_oxid PF01179.20 CRK39373.1 - 2.5e-148 494.4 0.0 3e-148 494.1 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 CRK39373.1 - 9.3e-05 22.6 0.1 0.0018 18.5 0.0 2.4 2 0 0 2 2 2 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 CRK39373.1 - 0.017 15.5 0.0 0.13 12.7 0.0 2.2 2 0 0 2 2 2 0 Copper amine oxidase, N3 domain Gly_transf_sug PF04488.15 CRK39376.1 - 2.9e-14 53.5 0.0 5.8e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Zn_clus PF00172.18 CRK39378.1 - 4e-05 23.6 10.6 7.9e-05 22.7 10.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAF-AH_p_II PF03403.13 CRK39381.1 - 1.2e-18 66.8 0.0 5.5e-09 35.0 0.0 2.4 2 1 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 CRK39381.1 - 2.3e-07 30.0 0.0 4.5e-07 29.0 0.0 1.4 2 0 0 2 2 2 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 CRK39381.1 - 3.3e-06 26.5 0.0 0.027 13.7 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CRK39381.1 - 0.00047 20.8 6.4 0.00047 20.8 6.4 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CRK39381.1 - 0.0048 16.6 0.3 0.35 10.5 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 CRK39381.1 - 0.012 15.4 0.0 4 7.2 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family Chlorophyllase PF07224.11 CRK39381.1 - 0.023 13.7 0.1 0.075 12.0 0.1 1.7 1 1 0 1 1 1 0 Chlorophyllase Glyco_hydro_31 PF01055.26 CRK39382.1 - 3.3e-27 95.8 0.5 3.5e-27 95.7 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 LIAS_N PF16881.5 CRK39384.1 - 5e-18 65.5 0.0 1.2e-17 64.3 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 CRK39384.1 - 1.4e-12 48.3 0.0 2.3e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Spore_GerAC PF05504.11 CRK39384.1 - 0.16 12.2 0.0 0.3 11.3 0.0 1.3 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal Pectate_lyase_3 PF12708.7 CRK39387.1 - 1.1e-91 306.5 10.1 1.2e-79 267.1 2.2 2.8 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 CRK39387.1 - 2.6e-07 30.2 1.7 0.031 14.0 0.2 3.3 3 0 0 3 3 3 2 N terminal extension of bacteriophage endosialidase Methyltrn_RNA_3 PF02598.17 CRK39389.1 - 1.9e-93 313.1 0.0 2.4e-93 312.8 0.0 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase Thioredoxin PF00085.20 CRK39390.1 - 8.6e-26 89.9 0.1 1.2e-25 89.4 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 CRK39390.1 - 1.5e-06 28.6 0.1 5.3e-06 26.9 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 CRK39390.1 - 1.9e-05 24.1 0.0 2.9e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 CRK39390.1 - 0.00017 21.5 0.1 0.00028 20.8 0.1 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 CRK39390.1 - 0.00021 21.6 0.0 0.00055 20.2 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.6 CRK39390.1 - 0.0061 16.3 0.0 0.0083 15.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 CRK39390.1 - 0.0091 15.7 0.2 0.028 14.1 0.2 1.7 1 1 1 2 2 2 1 Redoxin Thioredoxin_7 PF13899.6 CRK39390.1 - 0.0099 16.0 0.1 0.015 15.4 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin-like TP_methylase PF00590.20 CRK39392.1 - 1.1e-46 159.4 1.6 1.1e-46 159.4 1.6 1.7 2 0 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 CRK39392.1 - 3.5e-13 49.9 0.0 9.2e-13 48.5 0.0 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_M PF14824.6 CRK39392.1 - 7.9e-11 41.2 0.0 1.7e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Sirohm_synth_C PF14823.6 CRK39392.1 - 4.7e-10 39.0 0.2 7.8e-09 35.0 0.2 2.2 1 1 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal SpoU_sub_bind PF08032.12 CRK39392.1 - 0.016 15.4 0.0 0.044 14.1 0.0 1.7 1 0 0 1 1 1 0 RNA 2'-O ribose methyltransferase substrate binding DUF3168 PF11367.8 CRK39392.1 - 0.079 13.1 1.6 0.15 12.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3168) BROMI PF14961.6 CRK39392.1 - 0.48 7.8 0.3 3.4 4.9 0.0 1.9 2 0 0 2 2 2 0 Broad-minded protein F-box-like PF12937.7 CRK39396.1 - 0.003 17.4 0.1 0.0056 16.6 0.1 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CRK39396.1 - 0.2 11.6 0.4 0.6 10.1 0.0 2.0 2 0 0 2 2 2 0 F-box domain Amino_oxidase PF01593.24 CRK39397.1 - 3e-61 208.1 0.1 1.1e-58 199.6 0.1 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CRK39397.1 - 2.7e-10 40.3 0.2 5.9e-10 39.2 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CRK39397.1 - 3.8e-05 23.4 0.6 0.042 13.4 0.4 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CRK39397.1 - 0.021 14.1 0.1 0.054 12.7 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CRK39397.1 - 0.03 13.4 0.1 0.043 12.9 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 CRK39397.1 - 0.036 13.3 0.7 0.056 12.7 0.1 1.5 2 0 0 2 2 2 0 FAD binding domain AlaDh_PNT_C PF01262.21 CRK39397.1 - 0.048 12.9 0.3 0.11 11.7 0.1 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 CRK39397.1 - 0.049 14.2 0.5 1.4 9.5 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CRK39397.1 - 0.05 12.9 0.1 0.11 11.9 0.1 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 CRK39397.1 - 0.058 12.6 0.2 0.17 11.1 0.2 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CRK39397.1 - 0.086 11.9 0.4 0.17 10.9 0.4 1.5 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.17 CRK39397.1 - 0.16 11.2 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Amino_oxidase PF01593.24 CRK39398.1 - 3.9e-50 171.5 0.1 1.7e-33 116.6 0.0 3.0 2 1 1 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CRK39398.1 - 2.4e-26 91.7 0.1 1.2e-13 51.0 0.2 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CRK39398.1 - 1.8e-10 40.5 1.5 4.8e-05 22.7 0.6 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CRK39398.1 - 7.4e-10 38.5 0.6 6.8e-06 25.4 0.7 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 CRK39398.1 - 6.7e-09 35.8 7.2 0.0014 18.2 2.9 3.0 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 CRK39398.1 - 7.2e-08 32.1 0.9 0.00056 19.3 0.7 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox PF00070.27 CRK39398.1 - 1.4e-07 32.0 2.9 0.00028 21.4 1.4 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CRK39398.1 - 2.1e-07 30.4 0.3 5.9e-05 22.4 0.3 2.2 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 CRK39398.1 - 7.9e-07 28.1 1.3 0.00062 18.6 1.4 2.2 2 0 0 2 2 2 2 HI0933-like protein Lycopene_cycl PF05834.12 CRK39398.1 - 1.6e-06 27.4 0.2 0.011 14.9 0.2 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_9 PF13454.6 CRK39398.1 - 1.8e-06 28.0 0.4 0.022 14.7 0.0 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding FAD_oxidored PF12831.7 CRK39398.1 - 1e-05 25.1 0.0 2.3e-05 24.0 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 CRK39398.1 - 2.8e-05 23.5 0.0 0.0045 16.3 0.0 2.5 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.14 CRK39398.1 - 0.00018 20.5 1.6 0.18 10.6 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox_3 PF13738.6 CRK39398.1 - 0.00083 18.7 0.4 0.061 12.6 1.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 CRK39398.1 - 0.0016 18.5 0.3 0.011 15.8 0.2 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 CRK39398.1 - 0.0023 17.8 2.3 0.51 10.2 0.8 2.3 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 CRK39398.1 - 0.0035 16.5 0.7 0.066 12.3 0.7 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A FMO-like PF00743.19 CRK39398.1 - 0.0043 15.5 0.0 0.051 12.0 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Glu_dehyd_C PF16912.5 CRK39398.1 - 0.0051 16.3 0.0 0.24 10.9 0.0 2.2 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus TrkA_N PF02254.18 CRK39398.1 - 0.02 15.2 1.2 0.87 9.9 0.8 2.6 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_7 PF13241.6 CRK39398.1 - 0.021 15.3 0.6 0.096 13.1 0.4 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding ApbA PF02558.16 CRK39398.1 - 0.036 13.7 0.9 8.9 5.9 0.4 3.1 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 CRK39398.1 - 0.044 13.4 0.3 4 7.0 0.2 2.4 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain MCRA PF06100.11 CRK39398.1 - 0.048 12.5 0.1 4.8 5.9 0.0 2.1 2 0 0 2 2 2 0 MCRA family TOBE_3 PF12857.7 CRK39398.1 - 0.099 12.6 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 TOBE-like domain F420_oxidored PF03807.17 CRK39398.1 - 0.1 13.2 1.7 4.4 8.0 0.2 3.1 2 1 1 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent DUF2834 PF11196.8 CRK39399.1 - 0.00014 22.2 19.4 0.011 16.0 0.1 4.3 3 1 0 3 3 3 2 Protein of unknown function (DUF2834) Rer1 PF03248.13 CRK39399.1 - 0.0039 16.9 0.0 0.0086 15.8 0.0 1.6 1 1 0 1 1 1 1 Rer1 family PGM_PMM_IV PF00408.20 CRK39399.1 - 0.19 11.9 0.0 0.37 11.0 0.0 1.4 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, C-terminal domain Cytochrom_B561 PF03188.16 CRK39400.1 - 0.28 11.3 6.6 0.43 10.7 6.6 1.3 1 1 0 1 1 1 0 Eukaryotic cytochrome b561 DoxX_3 PF13781.6 CRK39400.1 - 1.8 9.2 11.4 0.62 10.7 6.6 2.1 2 0 0 2 2 2 0 DoxX-like family Phage_holin_2_4 PF16082.5 CRK39400.1 - 5.3 6.9 7.7 8.3 6.2 0.6 2.7 3 0 0 3 3 3 0 Bacteriophage holin family, superfamily II-like DUF4131 PF13567.6 CRK39400.1 - 5.8 6.5 9.1 0.47 10.1 0.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Methyltransf_25 PF13649.6 CRK39401.1 - 0.0054 17.4 0.1 0.027 15.2 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain VWA_CoxE PF05762.14 CRK39402.1 - 0.0067 15.9 0.0 0.022 14.2 0.0 1.8 2 0 0 2 2 2 1 VWA domain containing CoxE-like protein VWA_2 PF13519.6 CRK39402.1 - 0.021 15.5 0.0 0.15 12.8 0.0 2.2 1 1 0 1 1 1 0 von Willebrand factor type A domain VWA PF00092.28 CRK39402.1 - 0.068 13.4 0.0 2.6 8.3 0.0 2.4 1 1 1 2 2 2 0 von Willebrand factor type A domain Pkinase PF00069.25 CRK39402.1 - 0.087 12.2 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein kinase domain 3HCDH_N PF02737.18 CRK39403.1 - 0.062 13.2 0.9 0.11 12.4 0.7 1.5 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF262 PF03235.14 CRK39403.1 - 0.07 13.3 0.1 0.088 13.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF262 Cnn_1N PF07989.11 CRK39403.1 - 0.87 9.8 3.4 3.7 7.8 0.5 2.8 3 1 0 3 3 3 0 Centrosomin N-terminal motif 1 DASH_Spc19 PF08287.11 CRK39404.1 - 6e-43 146.4 0.0 9.1e-43 145.9 0.0 1.3 1 0 0 1 1 1 1 Spc19 SH3_1 PF00018.28 CRK39405.1 - 0.054 13.1 0.1 0.12 12.0 0.1 1.6 1 0 0 1 1 1 0 SH3 domain DUF4203 PF13886.6 CRK39405.1 - 0.82 9.3 12.2 1.2 8.7 12.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) DUF4064 PF13273.6 CRK39405.1 - 0.85 9.9 6.0 1.4 9.2 4.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) Dynactin_p22 PF07426.11 CRK39406.1 - 5.9e-06 26.3 0.0 7.5e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Dynactin subunit p22 CENP-T_N PF16171.5 CRK39406.1 - 0.0067 15.4 0.2 0.009 15.0 0.2 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T N-terminus Aa_trans PF01490.18 CRK39407.1 - 7.2e-91 304.9 14.7 1e-90 304.4 14.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CRK39407.1 - 8.4e-05 21.8 15.9 0.00017 20.8 15.9 1.5 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family Ribosomal_S16 PF00886.19 CRK39408.1 - 1.4e-23 82.7 0.2 5e-23 80.9 0.2 1.8 1 1 0 1 1 1 1 Ribosomal protein S16 YjeF_N PF03853.15 CRK39409.1 - 1e-34 119.9 0.0 1.3e-34 119.6 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus Zn_clus PF00172.18 CRK39410.1 - 1.5e-09 37.8 12.5 2.4e-09 37.1 12.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Merozoite_SPAM PF07133.11 CRK39411.1 - 0.092 12.7 25.2 0.14 12.1 25.2 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) TLP-20 PF06088.11 CRK39411.1 - 0.15 12.0 9.2 0.31 10.9 9.2 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Nucleo_P87 PF07267.11 CRK39411.1 - 0.53 9.1 11.4 0.71 8.7 11.4 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 RXT2_N PF08595.11 CRK39411.1 - 0.59 10.1 12.5 1.6 8.7 12.5 1.7 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF913 PF06025.12 CRK39411.1 - 1.7 7.5 7.7 2.7 6.9 7.7 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SAPS PF04499.15 CRK39411.1 - 2.5 6.8 7.1 2.5 6.8 7.1 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF1275 PF06912.11 CRK39413.1 - 3.4e-46 157.6 8.0 4.4e-46 157.2 8.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF3040 PF11239.8 CRK39413.1 - 0.01 16.1 1.4 0.17 12.1 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) DUF202 PF02656.15 CRK39413.1 - 0.019 15.4 1.3 0.019 15.4 1.3 4.0 4 1 0 4 4 4 0 Domain of unknown function (DUF202) DUF3953 PF13129.6 CRK39413.1 - 0.16 11.7 2.8 5.8 6.8 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3953) DUF3784 PF12650.7 CRK39413.1 - 0.19 11.9 2.1 0.74 10.0 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) DUF3408 PF11888.8 CRK39415.1 - 0.0029 17.8 7.2 0.0041 17.3 7.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3408) Macoilin PF09726.9 CRK39415.1 - 0.0047 15.6 13.6 0.005 15.5 13.6 1.0 1 0 0 1 1 1 1 Macoilin family Vfa1 PF08432.10 CRK39415.1 - 0.033 14.5 8.9 0.035 14.4 8.9 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RPN2_C PF18004.1 CRK39415.1 - 0.044 13.7 9.9 0.05 13.5 9.9 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF3807 PF12720.7 CRK39415.1 - 0.088 13.1 11.7 0.12 12.7 11.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) AAA_11 PF13086.6 CRK39415.1 - 0.11 12.3 6.6 0.12 12.2 6.6 1.1 1 0 0 1 1 1 0 AAA domain RNA_pol_Rpc4 PF05132.14 CRK39415.1 - 0.19 12.1 5.8 0.22 11.9 5.8 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 Connexin PF00029.19 CRK39415.1 - 0.2 11.4 5.2 0.25 11.0 5.2 1.1 1 0 0 1 1 1 0 Connexin Rtf2 PF04641.12 CRK39415.1 - 0.23 10.8 9.6 0.26 10.6 9.6 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger DUF3563 PF12086.8 CRK39415.1 - 0.25 11.1 0.2 0.25 11.1 0.2 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF3563) CPSF100_C PF13299.6 CRK39415.1 - 0.33 11.1 6.9 0.4 10.9 6.9 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF702 PF05142.12 CRK39415.1 - 0.36 11.3 5.6 0.45 11.0 5.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF702) DUF4746 PF15928.5 CRK39415.1 - 0.42 10.0 9.2 0.51 9.7 9.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CT47 PF15623.6 CRK39415.1 - 0.46 10.3 16.0 0.55 10.0 16.0 1.1 1 0 0 1 1 1 0 Cancer/testis gene family 47 DDHD PF02862.17 CRK39415.1 - 0.56 10.3 3.3 0.61 10.2 3.3 1.1 1 0 0 1 1 1 0 DDHD domain NPR3 PF03666.13 CRK39415.1 - 0.61 8.8 5.5 0.67 8.7 5.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4192 PF13830.6 CRK39415.1 - 0.7 9.9 9.2 0.8 9.7 9.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) Presenilin PF01080.17 CRK39415.1 - 1 8.0 6.6 1.1 7.9 6.6 1.1 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 CRK39415.1 - 1.4 7.2 9.5 1.4 7.2 9.5 1.1 1 0 0 1 1 1 0 CDC45-like protein ALMT PF11744.8 CRK39415.1 - 1.9 7.2 4.9 2.1 7.1 4.9 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter CLN3 PF02487.17 CRK39415.1 - 2.1 7.3 3.0 2.5 7.0 3.0 1.1 1 0 0 1 1 1 0 CLN3 protein DNA_pol_phi PF04931.13 CRK39415.1 - 2.2 6.3 11.5 2.5 6.1 11.5 1.0 1 0 0 1 1 1 0 DNA polymerase phi XRN_M PF17846.1 CRK39415.1 - 2.4 7.0 8.5 2.5 6.9 8.5 1.0 1 0 0 1 1 1 0 Xrn1 helical domain Kei1 PF08552.11 CRK39415.1 - 3.5 7.5 4.2 4.6 7.1 4.2 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DDRGK PF09756.9 CRK39415.1 - 4.1 6.9 19.0 5.3 6.6 19.0 1.1 1 0 0 1 1 1 0 DDRGK domain Hid1 PF12722.7 CRK39415.1 - 4.2 5.4 7.5 4.5 5.3 7.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Endonuc_Holl PF10107.9 CRK39415.1 - 4.8 7.0 8.9 6.2 6.7 8.9 1.2 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase Sec62 PF03839.16 CRK39415.1 - 5.4 6.5 9.4 6.6 6.2 9.4 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 SAPS PF04499.15 CRK39415.1 - 5.5 5.6 8.6 6.3 5.5 8.6 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein V_ATPase_I PF01496.19 CRK39415.1 - 7.4 4.3 6.2 7.5 4.3 6.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Pkinase PF00069.25 CRK39416.1 - 5.9e-57 193.0 0.0 9e-54 182.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CRK39416.1 - 2.6e-34 118.7 0.0 1.5e-32 112.9 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CRK39416.1 - 4.8e-05 22.8 0.0 7.3e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CRK39416.1 - 0.00032 19.8 0.0 0.00062 18.8 0.0 1.3 1 1 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 CRK39416.1 - 0.017 14.2 0.1 0.033 13.2 0.1 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 CRK39416.1 - 0.027 13.3 0.0 0.035 12.9 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase SUR7 PF06687.12 CRK39417.1 - 2e-38 132.2 6.1 2.6e-38 131.8 6.1 1.0 1 0 0 1 1 1 1 SUR7/PalI family Amastin PF07344.11 CRK39417.1 - 1.3 8.9 13.2 2.5 7.9 13.2 1.4 1 0 0 1 1 1 0 Amastin surface glycoprotein DUF4064 PF13273.6 CRK39417.1 - 2 8.8 10.2 11 6.3 1.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) Peptidase_C65 PF10275.9 CRK39418.1 - 4e-65 219.7 0.0 5.6e-65 219.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase C65 Otubain PCI PF01399.27 CRK39419.1 - 1e-17 64.5 0.6 2.6e-17 63.2 0.1 2.0 2 0 0 2 2 2 1 PCI domain DUF4423 PF14394.6 CRK39419.1 - 0.00083 19.1 0.4 0.22 11.2 0.1 2.9 3 1 0 3 3 3 2 Domain of unknown function (DUF4423) CvfB_WH PF17783.1 CRK39419.1 - 0.044 13.6 0.0 0.15 11.8 0.0 1.9 2 0 0 2 2 2 0 CvfB-like winged helix domain TPR_2 PF07719.17 CRK39419.1 - 0.2 11.8 5.3 0.82 9.9 0.6 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat CWC25 PF12542.8 CRK39420.1 - 1e-24 87.3 0.4 1e-24 87.3 0.4 4.0 3 3 1 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.9 CRK39420.1 - 2.4e-14 53.2 6.2 2.4e-14 53.2 6.2 4.0 5 1 1 6 6 6 1 N-terminal domain of CBF1 interacting co-repressor CIR Ras PF00071.22 CRK39421.1 - 9.7e-53 178.1 0.0 1.1e-52 177.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CRK39421.1 - 1.2e-21 77.1 0.0 2.1e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CRK39421.1 - 1.9e-08 34.0 0.0 4.4e-08 32.8 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CRK39421.1 - 0.00087 18.7 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 CRK39421.1 - 0.003 16.8 0.0 0.0086 15.3 0.0 1.4 1 1 0 1 1 1 1 G-protein alpha subunit SRPRB PF09439.10 CRK39421.1 - 0.011 15.2 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CRK39421.1 - 0.022 14.9 0.0 0.038 14.1 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 CRK39421.1 - 0.072 13.6 0.0 0.1 13.1 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Putative_PNPOx PF01243.20 CRK39423.1 - 6e-12 45.6 0.1 6.7e-11 42.2 0.1 2.2 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Mem_trans PF03547.18 CRK39424.1 - 1.2e-51 175.3 4.2 4e-51 173.6 4.2 1.7 1 1 0 1 1 1 1 Membrane transport protein DUF4360 PF14273.6 CRK39425.1 - 2.2e-63 213.4 2.5 2.5e-63 213.2 2.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Citrate_synt PF00285.21 CRK39426.1 - 2.7e-100 336.0 0.0 3.5e-100 335.6 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain ICL PF00463.21 CRK39427.1 - 4.6e-72 243.2 0.1 1.3e-52 179.0 0.0 2.0 1 1 1 2 2 2 2 Isocitrate lyase family adh_short_C2 PF13561.6 CRK39428.1 - 1.4e-58 198.3 0.5 1.6e-58 198.0 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRK39428.1 - 1.1e-40 139.2 0.1 1.4e-40 138.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CRK39428.1 - 1.1e-09 38.5 1.2 1.7e-09 37.8 1.2 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 CRK39428.1 - 0.00089 19.2 0.2 0.0019 18.1 0.2 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 CRK39428.1 - 0.0061 17.2 0.0 0.013 16.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CRK39428.1 - 0.029 14.2 0.0 0.086 12.7 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Polysacc_synt_2 PF02719.15 CRK39428.1 - 0.041 13.0 0.0 0.062 12.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RecC_C PF17946.1 CRK39428.1 - 0.047 13.5 0.1 0.083 12.7 0.1 1.3 1 0 0 1 1 1 0 RecC C-terminal domain Methyltransf_12 PF08242.12 CRK39428.1 - 0.051 14.3 0.0 0.11 13.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Epimerase PF01370.21 CRK39428.1 - 0.057 12.9 0.1 0.094 12.2 0.1 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family UDPG_MGDP_dh_N PF03721.14 CRK39428.1 - 0.097 12.2 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Gln-synt_C PF00120.24 CRK39429.1 - 2.6e-83 279.9 0.0 3.4e-83 279.5 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Methyltransf_23 PF13489.6 CRK39429.1 - 3.5e-22 79.0 0.0 8.3e-10 38.7 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 CRK39429.1 - 2.9e-19 69.5 0.0 5e-08 33.5 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 CRK39429.1 - 2.3e-15 56.7 0.0 2.6e-06 27.3 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 CRK39429.1 - 7.1e-13 49.1 0.0 9.5e-05 23.1 0.0 2.9 2 2 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 CRK39429.1 - 3.9e-11 43.5 0.0 0.00056 20.5 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain MTS PF05175.14 CRK39429.1 - 2.3e-09 37.0 0.0 0.0091 15.6 0.0 3.6 4 0 0 4 4 4 2 Methyltransferase small domain Methyltransf_4 PF02390.17 CRK39429.1 - 4.2e-09 36.1 0.0 0.0039 16.7 0.0 2.5 2 0 0 2 2 2 2 Putative methyltransferase FtsJ PF01728.19 CRK39429.1 - 3.3e-05 24.1 0.0 0.39 10.8 0.0 2.3 2 0 0 2 2 2 2 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 CRK39429.1 - 6e-05 22.5 0.0 0.77 9.0 0.0 3.3 2 2 0 2 2 2 2 ubiE/COQ5 methyltransferase family DUF389 PF04087.14 CRK39429.1 - 0.00039 20.5 10.2 0.73 9.9 0.7 3.3 3 0 0 3 3 3 2 Domain of unknown function (DUF389) Methyltransf_16 PF10294.9 CRK39429.1 - 0.00092 19.0 0.0 1.9 8.2 0.0 2.3 2 0 0 2 2 2 2 Lysine methyltransferase Methyltransf_2 PF00891.18 CRK39429.1 - 0.0013 18.1 0.0 1.9 7.8 0.0 2.3 2 0 0 2 2 2 2 O-methyltransferase domain Rsm22 PF09243.10 CRK39429.1 - 0.0024 17.2 0.0 2.4 7.3 0.0 2.3 2 0 0 2 2 2 2 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_8 PF05148.15 CRK39429.1 - 0.0052 16.7 0.0 4.4 7.1 0.0 2.4 2 0 0 2 2 2 2 Hypothetical methyltransferase DUF938 PF06080.12 CRK39429.1 - 0.0089 15.8 0.0 6.1 6.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF938) PrmA PF06325.13 CRK39429.1 - 0.02 14.3 0.3 6.2 6.1 0.0 2.2 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) SSF PF00474.17 CRK39430.1 - 5e-22 78.3 28.4 8.9e-22 77.5 28.4 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family p450 PF00067.22 CRK39431.1 - 1.3e-55 189.0 0.0 1.6e-55 188.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NS3_envE PF02723.14 CRK39432.1 - 0.011 15.7 0.0 0.019 15.0 0.0 1.4 1 0 0 1 1 1 0 Non-structural protein NS3/Small envelope protein E DUF4342 PF14242.6 CRK39432.1 - 0.17 11.9 0.1 0.17 11.9 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4342) Aa_trans PF01490.18 CRK39433.1 - 9.7e-51 172.7 5.7 1.4e-50 172.2 5.7 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Abhydrolase_9_N PF15420.6 CRK39433.1 - 0.0098 15.9 2.8 0.15 12.1 0.2 2.8 2 1 0 2 2 2 1 Alpha/beta-hydrolase family N-terminus YfhO PF09586.10 CRK39433.1 - 0.053 11.8 0.9 0.072 11.3 0.9 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO FSH1 PF03959.13 CRK39433.1 - 0.092 12.4 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Ribosomal_S16 PF00886.19 CRK39434.1 - 1.1e-23 83.0 0.3 4.4e-23 81.1 0.3 1.8 1 1 0 1 1 1 1 Ribosomal protein S16 YjeF_N PF03853.15 CRK39436.1 - 4.6e-28 98.2 0.0 6.3e-28 97.8 0.0 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus Glyco_hydro_16 PF00722.21 CRK39441.1 - 1.1e-36 126.0 0.1 1.9e-36 125.2 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 CcmD PF04995.14 CRK39441.1 - 0.069 13.2 0.9 0.15 12.2 0.9 1.5 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) VEGFR-2_TMD PF17988.1 CRK39441.1 - 0.18 11.3 0.1 0.33 10.4 0.1 1.4 1 0 0 1 1 1 0 VEGFR-2 Transmembrane domain DUF1275 PF06912.11 CRK39443.1 - 1.6e-46 158.7 8.4 2.1e-46 158.3 8.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF202 PF02656.15 CRK39443.1 - 0.0058 17.1 1.3 0.0058 17.1 1.3 4.0 4 1 0 4 4 4 1 Domain of unknown function (DUF202) DUF3040 PF11239.8 CRK39443.1 - 0.012 15.9 1.3 0.13 12.6 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) DUF3784 PF12650.7 CRK39443.1 - 0.21 11.8 2.3 0.85 9.9 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) DUF3953 PF13129.6 CRK39443.1 - 0.27 11.0 2.6 5.8 6.8 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3953) BUD22 PF09073.10 CRK39446.1 - 0.012 15.0 16.6 0.014 14.7 16.6 1.0 1 0 0 1 1 1 0 BUD22 DUF4192 PF13830.6 CRK39446.1 - 0.14 12.2 15.3 0.16 12.0 15.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) Raftlin PF15250.6 CRK39446.1 - 0.14 10.9 4.8 0.14 10.9 4.8 1.0 1 0 0 1 1 1 0 Raftlin UPA_2 PF17809.1 CRK39446.1 - 0.16 11.8 1.3 0.19 11.6 1.3 1.1 1 0 0 1 1 1 0 UPA domain Vfa1 PF08432.10 CRK39446.1 - 0.17 12.2 14.6 0.21 11.9 14.6 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Asp-B-Hydro_N PF05279.11 CRK39446.1 - 0.19 11.7 17.4 0.22 11.5 17.4 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region RNA_pol_Rpc4 PF05132.14 CRK39446.1 - 0.2 12.1 6.5 0.27 11.7 6.5 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Nop53 PF07767.11 CRK39446.1 - 0.24 10.7 22.2 0.29 10.5 22.2 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF3563 PF12086.8 CRK39446.1 - 0.3 10.9 0.1 0.3 10.9 0.1 3.2 2 1 1 3 3 2 0 Protein of unknown function (DUF3563) Rtf2 PF04641.12 CRK39446.1 - 0.3 10.4 14.6 0.38 10.1 14.6 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger NPR3 PF03666.13 CRK39446.1 - 0.37 9.5 7.0 0.42 9.4 7.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CPSF100_C PF13299.6 CRK39446.1 - 0.4 10.9 8.5 0.52 10.5 8.5 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DNA_pol_phi PF04931.13 CRK39446.1 - 0.71 7.9 15.5 0.82 7.7 15.5 1.0 1 0 0 1 1 1 0 DNA polymerase phi TraV PF09676.10 CRK39446.1 - 0.74 10.8 8.8 1 10.4 8.8 1.3 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) ALMT PF11744.8 CRK39446.1 - 0.79 8.5 8.1 0.96 8.2 8.1 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF2151 PF10221.9 CRK39446.1 - 0.94 8.0 9.7 1.1 7.8 9.7 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator DDHD PF02862.17 CRK39446.1 - 0.99 9.5 4.1 1.1 9.4 4.1 1.2 1 0 0 1 1 1 0 DDHD domain Borrelia_P83 PF05262.11 CRK39446.1 - 1.1 7.7 18.8 1.2 7.6 18.8 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF4569 PF15133.6 CRK39446.1 - 1.4 8.6 6.0 1.6 8.4 6.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) DUF913 PF06025.12 CRK39446.1 - 1.5 7.7 5.7 1.7 7.6 5.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 CRK39446.1 - 1.5 7.5 11.4 1.7 7.3 11.4 1.1 1 0 0 1 1 1 0 Presenilin AAA_11 PF13086.6 CRK39446.1 - 1.6 8.5 11.4 1.7 8.3 11.4 1.1 1 0 0 1 1 1 0 AAA domain CDC45 PF02724.14 CRK39446.1 - 1.7 6.8 16.6 1.9 6.6 16.6 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF3408 PF11888.8 CRK39446.1 - 1.7 8.7 17.9 13 5.9 17.9 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3408) DUF4407 PF14362.6 CRK39446.1 - 1.8 7.8 15.5 2.2 7.6 15.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MAJIN PF15077.6 CRK39446.1 - 1.9 8.2 6.9 2.1 8.0 6.9 1.1 1 0 0 1 1 1 0 Membrane-anchored junction protein SLC12 PF03522.15 CRK39446.1 - 2 7.3 6.9 2.2 7.2 6.9 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF4228 PF14009.6 CRK39446.1 - 2.9 8.2 9.1 3.6 8.0 9.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) DUF4746 PF15928.5 CRK39446.1 - 4 6.8 15.4 4.8 6.5 15.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Macoilin PF09726.9 CRK39446.1 - 4.4 5.7 16.4 5.9 5.3 16.4 1.3 1 0 0 1 1 1 0 Macoilin family Hid1 PF12722.7 CRK39446.1 - 5.3 5.0 10.2 6.3 4.8 10.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SID-1_RNA_chan PF13965.6 CRK39446.1 - 5.7 5.2 4.2 6.5 5.0 4.2 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Paramyxo_ncap PF00973.19 CRK39446.1 - 5.9 5.7 9.2 6.8 5.5 9.2 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein CLN3 PF02487.17 CRK39446.1 - 6.3 5.7 5.1 7.1 5.6 5.1 1.1 1 0 0 1 1 1 0 CLN3 protein XRN_M PF17846.1 CRK39446.1 - 6.4 5.6 12.2 7.5 5.4 12.2 1.1 1 0 0 1 1 1 0 Xrn1 helical domain SAPS PF04499.15 CRK39446.1 - 7.2 5.3 10.9 8 5.1 10.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Sec62 PF03839.16 CRK39446.1 - 9.2 5.7 12.6 12 5.4 12.6 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Kei1 PF08552.11 CRK39446.1 - 9.4 6.1 7.1 13 5.6 7.1 1.3 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 V_ATPase_I PF01496.19 CRK39446.1 - 9.5 4.0 7.6 9.7 4.0 7.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Pkinase PF00069.25 CRK39447.1 - 1.8e-56 191.4 0.0 2.9e-53 180.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CRK39447.1 - 5.7e-34 117.6 0.0 2.1e-32 112.5 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CRK39447.1 - 4.7e-05 22.9 0.0 7e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CRK39447.1 - 0.00029 19.9 0.0 0.0006 18.9 0.0 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 CRK39447.1 - 0.016 14.2 0.2 0.032 13.3 0.1 1.5 2 0 0 2 2 2 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 CRK39447.1 - 0.026 13.3 0.0 0.034 12.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase SUR7 PF06687.12 CRK39449.1 - 1.5e-37 129.3 7.8 2e-37 128.9 7.8 1.0 1 0 0 1 1 1 1 SUR7/PalI family Amastin PF07344.11 CRK39449.1 - 1.2 9.0 13.2 2.5 7.9 13.2 1.5 1 0 0 1 1 1 0 Amastin surface glycoprotein DUF4064 PF13273.6 CRK39449.1 - 4.1 7.8 11.1 11 6.3 1.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) BPL_LplA_LipB PF03099.19 CRK39453.1 - 0.00014 21.8 0.0 0.00028 20.8 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family DUF1658 PF07871.11 CRK39455.1 - 0.066 13.2 1.5 0.41 10.7 1.5 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1658) PCI PF01399.27 CRK39456.1 - 1.4e-16 60.9 1.1 3.8e-16 59.5 0.1 2.2 2 0 0 2 2 2 1 PCI domain DUF4423 PF14394.6 CRK39456.1 - 0.0019 17.9 0.5 0.23 11.2 0.1 2.9 3 1 0 3 3 3 1 Domain of unknown function (DUF4423) TPR_1 PF00515.28 CRK39456.1 - 0.02 14.7 0.6 10 6.1 0.2 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 CRK39456.1 - 0.031 14.4 5.2 0.82 9.9 0.6 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat CvfB_WH PF17783.1 CRK39456.1 - 0.047 13.5 0.1 0.15 11.8 0.0 1.9 2 0 0 2 2 2 0 CvfB-like winged helix domain CWC25 PF12542.8 CRK39457.1 - 1e-24 87.3 0.4 1e-24 87.3 0.4 4.1 2 2 1 3 3 3 1 Pre-mRNA splicing factor Cir_N PF10197.9 CRK39457.1 - 2.4e-14 53.2 6.2 2.4e-14 53.2 6.2 4.1 5 1 1 6 6 6 1 N-terminal domain of CBF1 interacting co-repressor CIR Ras PF00071.22 CRK39458.1 - 9.6e-53 178.1 0.0 1.1e-52 177.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CRK39458.1 - 1.2e-21 77.1 0.0 2.1e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CRK39458.1 - 1.3e-08 34.5 0.0 3e-08 33.3 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CRK39458.1 - 0.00062 19.2 0.0 0.00074 18.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 CRK39458.1 - 0.003 16.8 0.0 0.0076 15.5 0.0 1.4 1 1 0 1 1 1 1 G-protein alpha subunit SRPRB PF09439.10 CRK39458.1 - 0.011 15.2 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CRK39458.1 - 0.021 14.9 0.0 0.038 14.1 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 CRK39458.1 - 0.071 13.6 0.0 0.1 13.1 0.0 1.4 1 0 0 1 1 1 0 ABC transporter CPSase_L_D2 PF02786.17 CRK39459.1 - 3.4e-72 242.4 0.0 5e-72 241.8 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 CRK39459.1 - 8.8e-38 128.7 0.0 1.8e-37 127.8 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 CRK39459.1 - 2e-36 124.9 0.0 5.1e-36 123.6 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 CRK39459.1 - 3.3e-15 55.7 1.6 3.3e-15 55.7 1.6 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme ATP-grasp PF02222.22 CRK39459.1 - 5.1e-08 32.7 0.0 1e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 CRK39459.1 - 1.8e-07 30.8 1.0 0.0042 16.9 0.0 3.5 2 1 1 3 3 3 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 CRK39459.1 - 1e-06 28.5 0.0 2.6e-06 27.1 0.0 1.7 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus HlyD_3 PF13437.6 CRK39459.1 - 4.9e-05 24.0 0.2 0.37 11.5 0.0 3.3 3 0 0 3 3 3 2 HlyD family secretion protein RimK PF08443.11 CRK39459.1 - 0.0027 17.3 0.0 0.021 14.4 0.0 2.1 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 CRK39459.1 - 0.0046 17.0 0.0 0.0087 16.1 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain HlyD_D23 PF16576.5 CRK39459.1 - 0.019 14.2 0.1 2.4 7.3 0.0 2.6 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATPgrasp_ST PF14397.6 CRK39459.1 - 0.13 11.5 0.0 0.54 9.4 0.0 1.8 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Putative_PNPOx PF01243.20 CRK39460.1 - 4.8e-11 42.7 0.1 1.2e-10 41.4 0.0 1.7 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Mem_trans PF03547.18 CRK39461.1 - 4.4e-51 173.5 4.6 1.5e-50 171.8 4.6 1.7 1 1 0 1 1 1 1 Membrane transport protein Ank_4 PF13637.6 CRK39462.1 - 4.5e-20 71.8 0.0 1.1e-09 38.6 0.1 3.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 CRK39462.1 - 6.2e-17 61.2 2.9 1.6e-07 31.4 0.0 4.6 4 1 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 CRK39462.1 - 3.3e-16 59.1 0.1 1.4e-09 38.0 0.1 3.6 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 CRK39462.1 - 6.5e-16 58.7 0.0 2.2e-07 31.4 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CRK39462.1 - 4e-10 39.0 0.3 0.077 13.6 0.0 5.2 4 1 0 4 4 4 3 Ankyrin repeat Pkinase PF00069.25 CRK39463.1 - 2.4e-30 105.8 0.0 7.4e-30 104.2 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK39463.1 - 1.2e-07 31.2 0.1 1e-06 28.2 0.1 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CRK39463.1 - 0.0084 14.9 0.0 0.019 13.8 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 CRK39463.1 - 0.098 12.3 0.0 0.24 11.0 0.0 1.5 2 0 0 2 2 2 0 RIO1 family Kinase-like PF14531.6 CRK39463.1 - 0.15 11.4 0.0 0.68 9.2 0.0 1.9 2 0 0 2 2 2 0 Kinase-like DUF4360 PF14273.6 CRK39464.1 - 1.8e-63 213.6 2.9 2.1e-63 213.4 2.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Citrate_synt PF00285.21 CRK39465.1 - 3.2e-104 348.9 0.0 7.7e-100 334.5 0.0 2.1 2 0 0 2 2 2 2 Citrate synthase, C-terminal domain DUF5564 PF17719.1 CRK39465.1 - 0.042 14.0 0.2 16 5.7 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5564) ICL PF00463.21 CRK39466.1 - 2.3e-196 653.4 0.1 2.8e-196 653.1 0.1 1.1 1 0 0 1 1 1 1 Isocitrate lyase family DUF2458 PF10454.9 CRK39466.1 - 0.075 12.7 0.1 0.17 11.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) adh_short_C2 PF13561.6 CRK39468.1 - 7.9e-59 199.1 0.5 9.1e-59 198.8 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRK39468.1 - 6.9e-41 139.8 0.1 8.5e-41 139.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CRK39468.1 - 7.3e-10 39.0 1.2 1.1e-09 38.4 1.2 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 CRK39468.1 - 0.00072 19.5 0.2 0.0014 18.6 0.2 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 CRK39468.1 - 0.0043 17.7 0.0 0.0089 16.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CRK39468.1 - 0.019 14.8 0.0 0.061 13.2 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Polysacc_synt_2 PF02719.15 CRK39468.1 - 0.029 13.5 0.0 0.045 12.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Methyltransf_12 PF08242.12 CRK39468.1 - 0.035 14.8 0.0 0.075 13.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain RecC_C PF17946.1 CRK39468.1 - 0.035 13.9 0.1 0.062 13.1 0.1 1.3 1 0 0 1 1 1 0 RecC C-terminal domain Epimerase PF01370.21 CRK39468.1 - 0.046 13.2 0.1 0.063 12.7 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family UDPG_MGDP_dh_N PF03721.14 CRK39468.1 - 0.076 12.6 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain THF_DHG_CYH_C PF02882.19 CRK39468.1 - 0.08 12.3 0.0 0.31 10.3 0.0 1.9 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ChuX_HutX PF06228.13 CRK39468.1 - 0.12 12.1 0.0 15 5.4 0.0 2.3 1 1 0 2 2 2 0 Haem utilisation ChuX/HutX Gln-synt_C PF00120.24 CRK39469.1 - 1.9e-83 280.3 0.0 2.6e-83 279.9 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain SSF PF00474.17 CRK39469.1 - 1.2e-17 63.9 20.8 1.8e-17 63.3 20.8 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family p450 PF00067.22 CRK39470.1 - 1.5e-53 182.2 0.0 1.9e-53 181.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ABC_tran PF00005.27 CRK39471.1 - 0.0027 18.2 0.0 0.0048 17.4 0.0 1.5 1 1 0 1 1 1 1 ABC transporter TRAM_LAG1_CLN8 PF03798.16 CRK39472.1 - 1.4e-44 152.2 21.1 1.4e-44 152.2 21.1 1.8 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 CRK39472.1 - 2e-22 78.6 0.1 2e-22 78.6 0.1 2.3 2 0 0 2 2 2 1 TRAM1-like protein PP1_bind PF15276.6 CRK39472.1 - 0.074 13.4 0.2 0.15 12.4 0.2 1.4 1 0 0 1 1 1 0 Protein phosphatase 1 binding Bax1-I PF01027.20 CRK39473.1 - 8.8e-44 149.8 20.6 1.1e-43 149.5 20.6 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF5504 PF17608.2 CRK39473.1 - 1.3 9.1 10.9 0.19 11.9 5.2 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5504) DUF4131 PF13567.6 CRK39473.1 - 2.6 7.7 8.7 6.8 6.3 2.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Septin PF00735.18 CRK39475.1 - 5.7e-107 357.2 0.0 1e-106 356.4 0.0 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 CRK39475.1 - 0.0001 22.3 0.0 0.00026 21.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 CRK39475.1 - 0.01 15.9 4.0 2.3 8.3 0.0 3.1 2 1 1 3 3 3 0 Dynamin family RsgA_GTPase PF03193.16 CRK39475.1 - 0.029 14.3 0.6 0.029 14.3 0.6 2.2 2 1 0 2 2 2 0 RsgA GTPase AAA_23 PF13476.6 CRK39475.1 - 0.07 13.6 3.8 16 6.0 3.5 2.2 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 CRK39475.1 - 0.081 13.2 0.4 0.52 10.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.27 CRK39475.1 - 0.085 12.4 1.5 0.12 11.9 0.0 1.9 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain WD40 PF00400.32 CRK39476.1 - 1.1e-07 32.4 0.1 0.066 14.1 0.0 3.7 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK39476.1 - 0.00019 21.7 0.0 0.48 10.8 0.0 2.6 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 CRK39476.1 - 0.017 14.5 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal RRM_1 PF00076.22 CRK39477.1 - 9.3e-15 54.2 0.0 2.6e-13 49.6 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CRK39477.1 - 0.0012 18.9 0.0 0.0058 16.7 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif Tenui_NS3 PF05310.12 CRK39477.1 - 0.093 12.8 1.9 0.15 12.2 1.9 1.2 1 0 0 1 1 1 0 Tenuivirus movement protein DLIC PF05783.11 CRK39478.1 - 4.9e-23 81.7 0.0 2.8e-21 75.9 0.0 2.3 2 1 0 2 2 2 2 Dynein light intermediate chain (DLIC) Thioredox_DsbH PF03190.15 CRK39479.1 - 9.7e-60 201.2 0.0 1.5e-59 200.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 CRK39479.1 - 1.6e-06 28.2 0.0 3.3e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Sigma70_r4 PF04545.16 CRK39479.1 - 0.024 14.2 0.2 0.071 12.7 0.2 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 MFS_1 PF07690.16 CRK39480.1 - 2.8e-20 72.6 29.4 2.8e-20 72.6 29.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DIOX_N PF14226.6 CRK39482.1 - 2.8e-20 73.3 0.0 1.5e-19 70.9 0.0 2.0 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 CRK39482.1 - 1.3e-10 41.6 0.0 2.3e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF2299 PF10061.9 CRK39485.1 - 0.0009 19.0 0.0 0.0013 18.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2299) Homeobox_KN PF05920.11 CRK39488.1 - 1e-13 50.9 1.1 3.1e-13 49.4 1.1 1.9 1 0 0 1 1 1 1 Homeobox KN domain HTH_Tnp_Tc5 PF03221.16 CRK39488.1 - 4.8e-08 32.9 1.1 0.00096 19.1 0.0 3.6 3 1 0 3 3 3 2 Tc5 transposase DNA-binding domain Homeodomain PF00046.29 CRK39488.1 - 7.9e-07 28.8 0.5 7.9e-07 28.8 0.5 2.3 2 0 0 2 2 2 1 Homeodomain zf-C2H2_4 PF13894.6 CRK39488.1 - 0.0041 17.9 5.1 0.0041 17.9 5.1 5.7 5 0 0 5 5 5 1 C2H2-type zinc finger zf-C2H2 PF00096.26 CRK39488.1 - 0.01 16.2 28.5 0.016 15.6 5.4 5.2 5 0 0 5 5 5 0 Zinc finger, C2H2 type Podoplanin PF05808.11 CRK39488.1 - 0.12 12.5 1.4 0.25 11.4 1.4 1.5 1 0 0 1 1 1 0 Podoplanin BIR PF00653.21 CRK39488.1 - 0.6 10.8 8.1 0.91 10.2 0.1 3.1 2 1 1 3 3 3 0 Inhibitor of Apoptosis domain zf-FCS PF06467.14 CRK39488.1 - 2.8 7.9 6.4 4.6 7.3 1.5 3.2 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif DUF2828 PF11443.8 CRK39490.1 - 0.18 9.9 7.2 0.4 8.7 6.8 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) DUF874 PF05917.11 CRK39490.1 - 0.34 9.9 10.0 0.54 9.2 10.0 1.2 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) SRP-alpha_N PF04086.13 CRK39490.1 - 1.8 8.4 15.1 2.4 8.0 6.9 2.2 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal CCDC53 PF10152.9 CRK39490.1 - 4.4 7.7 13.3 1.6 9.1 4.9 2.8 3 0 0 3 3 3 0 Subunit CCDC53 of WASH complex Borrelia_P83 PF05262.11 CRK39490.1 - 4.5 5.6 9.7 6.9 5.0 9.7 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF4407 PF14362.6 CRK39490.1 - 6.7 6.0 12.4 13 5.0 12.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) V_ATPase_I PF01496.19 CRK39490.1 - 6.9 4.5 7.6 11 3.8 7.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Connexin PF00029.19 CRK39490.1 - 7.9 6.2 8.5 5.1 6.8 6.4 1.6 2 0 0 2 2 2 0 Connexin Pyrid_ox_like PF16242.5 CRK39520.1 - 0.043 13.4 0.1 0.059 13.0 0.1 1.2 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase like Kelch_3 PF13415.6 CRK39521.1 - 0.00014 22.0 4.6 0.028 14.7 0.0 4.3 3 1 1 4 4 4 2 Galactose oxidase, central domain Kelch_4 PF13418.6 CRK39521.1 - 0.00039 20.4 0.9 0.48 10.5 0.0 3.9 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.6 CRK39521.1 - 0.0005 20.0 0.6 0.01 15.8 0.1 3.3 3 0 0 3 3 3 1 Kelch motif Kelch_1 PF01344.25 CRK39521.1 - 0.0014 18.2 4.0 0.84 9.3 0.1 4.0 3 1 0 3 3 3 2 Kelch motif LST1 PF05083.13 CRK39521.1 - 0.024 14.9 0.0 0.061 13.6 0.0 1.6 1 0 0 1 1 1 0 LST-1 protein Adeno_E3_CR2 PF02439.15 CRK39521.1 - 0.44 10.3 1.4 0.83 9.5 1.4 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Ras PF00071.22 CRK39523.1 - 1.5e-59 200.3 0.2 1.7e-59 200.0 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CRK39523.1 - 1.8e-20 73.4 0.0 2.7e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CRK39523.1 - 3.1e-08 33.3 0.0 3.4e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CRK39523.1 - 6e-06 25.9 0.1 4.2e-05 23.2 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CRK39523.1 - 0.00018 21.5 0.4 0.68 9.8 0.0 2.4 1 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 CRK39523.1 - 0.0017 18.4 0.0 0.0026 17.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 CRK39523.1 - 0.0049 16.9 0.0 0.0094 16.0 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain FeoB_N PF02421.18 CRK39523.1 - 0.005 16.4 0.0 0.0093 15.5 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B ATP_bind_1 PF03029.17 CRK39523.1 - 0.15 11.8 1.3 2.1 8.0 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein MoCF_biosynth PF00994.24 CRK39524.1 - 8.2e-32 109.9 0.0 1.4e-31 109.1 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain Cofilin_ADF PF00241.20 CRK39525.1 - 2.8e-17 62.6 0.0 4.1e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Csm1 PF12539.8 CRK39525.1 - 0.13 12.9 0.3 0.28 11.9 0.2 1.5 1 1 0 1 1 1 0 Chromosome segregation protein Csm1/Pcs1 HEAT_2 PF13646.6 CRK39526.1 - 7.3e-38 128.9 11.9 2.3e-13 50.4 0.2 4.6 3 2 1 4 4 4 3 HEAT repeats HEAT_PBS PF03130.16 CRK39526.1 - 7.2e-27 91.3 10.2 0.028 15.0 0.0 8.9 8 0 0 8 8 8 6 PBS lyase HEAT-like repeat HEAT PF02985.22 CRK39526.1 - 9.3e-15 53.5 8.7 0.092 13.1 0.0 8.0 9 0 0 9 9 9 3 HEAT repeat HEAT_EZ PF13513.6 CRK39526.1 - 6.9e-09 36.0 13.4 0.17 12.5 0.1 7.1 6 1 2 8 8 8 3 HEAT-like repeat Arm PF00514.23 CRK39526.1 - 5.7e-06 26.2 6.9 0.35 11.0 0.0 5.2 6 0 0 6 6 6 3 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 CRK39526.1 - 3.3e-05 24.0 0.1 3.9 7.5 0.0 4.3 2 1 3 5 5 5 2 non-SMC mitotic condensation complex subunit 1 AroM PF07302.11 CRK39526.1 - 0.036 13.5 1.0 0.093 12.1 0.0 2.1 3 0 0 3 3 3 0 AroM protein PH_6 PF15406.6 CRK39526.1 - 0.13 12.5 0.1 16 5.8 0.0 2.5 1 1 1 2 2 2 0 Pleckstrin homology domain TPR_20 PF14561.6 CRK39526.1 - 2.1 8.7 4.9 34 4.9 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TFIIS_C PF01096.18 CRK39527.1 - 1e-17 63.6 2.3 1e-17 63.6 2.3 2.7 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 CRK39527.1 - 0.00036 20.4 2.0 0.00036 20.4 2.0 2.8 3 1 0 3 3 3 1 RNA polymerases M/15 Kd subunit Zn_ribbon_recom PF13408.6 CRK39527.1 - 0.094 13.2 0.3 0.094 13.2 0.3 2.5 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain Lar_restr_allev PF14354.6 CRK39527.1 - 0.36 11.2 11.7 1.3 9.5 0.8 3.2 2 1 0 2 2 2 0 Restriction alleviation protein Lar TF_Zn_Ribbon PF08271.12 CRK39527.1 - 0.38 10.3 7.7 6.4 6.4 0.2 2.8 2 1 0 2 2 2 0 TFIIB zinc-binding Zn_ribbon_SprT PF17283.2 CRK39527.1 - 1.6 8.7 11.6 1.7 8.6 0.5 3.4 3 0 0 3 3 3 0 SprT-like zinc ribbon domain Zn-ribbon_8 PF09723.10 CRK39527.1 - 1.7 8.8 0.0 1.7 8.8 0.0 2.8 3 0 0 3 3 3 0 Zinc ribbon domain zinc_ribbon_2 PF13240.6 CRK39527.1 - 1.9 8.3 18.3 1.5 8.6 0.5 3.9 4 0 0 4 4 4 0 zinc-ribbon domain Ribosomal_S27e PF01667.17 CRK39527.1 - 3.5 7.4 8.9 4.6 7.0 2.3 2.8 3 1 0 3 3 3 0 Ribosomal protein S27 zf-IS66 PF13005.7 CRK39527.1 - 9.3 6.7 13.1 11 6.5 0.1 3.8 4 0 0 4 4 4 0 zinc-finger binding domain of transposase IS66 Nipped-B_C PF12830.7 CRK39529.1 - 1.9e-94 315.0 13.9 3.3e-47 160.9 0.3 4.6 5 2 0 5 5 4 2 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 CRK39529.1 - 1.5e-12 47.6 12.5 9.1e-06 25.9 0.1 5.3 6 0 0 6 6 5 2 HEAT repeat associated with sister chromatid cohesion Adaptin_N PF01602.20 CRK39529.1 - 2.6e-12 46.1 0.2 6.6e-05 21.7 0.0 3.6 3 0 0 3 3 3 2 Adaptin N terminal region Cnd1 PF12717.7 CRK39529.1 - 6.3e-12 45.8 6.0 0.00031 20.8 0.1 4.7 2 2 2 4 4 4 4 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CRK39529.1 - 5.8e-11 41.7 18.6 0.14 12.5 0.0 9.6 9 0 0 9 9 8 2 HEAT repeat HEAT_EZ PF13513.6 CRK39529.1 - 6.6e-06 26.5 4.2 25 5.5 0.1 7.1 6 0 0 6 6 6 0 HEAT-like repeat HEAT_2 PF13646.6 CRK39529.1 - 0.00021 21.6 7.9 3.3 8.1 0.1 7.2 6 2 2 8 8 8 3 HEAT repeats IMD PF08397.11 CRK39529.1 - 0.0016 17.8 0.0 0.98 8.8 0.0 2.8 2 0 0 2 2 2 2 IRSp53/MIM homology domain Cnd3 PF12719.7 CRK39529.1 - 0.0021 17.3 0.2 3.7 6.6 0.0 3.5 3 0 0 3 3 3 2 Nuclear condensing complex subunits, C-term domain PhoD_N PF16655.5 CRK39529.1 - 0.025 15.1 0.0 0.079 13.5 0.0 1.8 1 0 0 1 1 1 0 PhoD-like phosphatase, N-terminal domain RasGEF_N_2 PF14663.6 CRK39529.1 - 0.026 14.9 0.0 56 4.2 0.0 4.9 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Vac14_Fab1_bd PF12755.7 CRK39529.1 - 0.037 14.6 0.3 2.5e+02 2.3 0.0 5.2 2 2 2 4 4 4 0 Vacuolar 14 Fab1-binding region Ribosomal_L36e PF01158.18 CRK39529.1 - 0.044 14.0 0.5 25 5.2 0.1 3.3 2 0 0 2 2 2 0 Ribosomal protein L36e ArdA PF07275.11 CRK39529.1 - 0.11 13.1 0.3 62 4.1 0.0 3.8 4 0 0 4 4 4 0 Antirestriction protein (ArdA) FNIP_N PF14636.6 CRK39530.1 - 4.1e-38 131.8 0.0 4.1e-38 131.8 0.0 4.4 4 1 0 4 4 4 1 Folliculin-interacting protein N-terminus FNIP_C PF14638.6 CRK39530.1 - 0.0028 17.3 0.1 0.012 15.3 0.1 2.1 1 1 0 1 1 1 1 Folliculin-interacting protein C-terminus IML1 PF12257.8 CRK39531.1 - 1.2e-129 431.5 6.6 7.5e-75 251.7 1.0 2.1 1 1 1 2 2 2 2 Vacuolar membrane-associated protein Iml1 Ribosomal_S2 PF00318.20 CRK39531.1 - 0.014 14.6 0.2 5.7 6.1 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein S2 IML1 PF12257.8 CRK39533.1 - 2.1e-36 125.5 0.0 3.1e-36 125.0 0.0 1.2 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 CRK39533.1 - 7.9e-27 93.1 0.2 1.4e-26 92.3 0.2 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PhoD_N PF16655.5 CRK39535.1 - 0.034 14.7 0.0 0.081 13.5 0.0 1.6 1 0 0 1 1 1 0 PhoD-like phosphatase, N-terminal domain PBP_N PF17093.5 CRK39535.1 - 4.2 7.6 8.4 3.1 8.0 1.2 2.7 2 0 0 2 2 2 0 Penicillin-binding protein N-terminus TFIIS_C PF01096.18 CRK39537.1 - 4.7e-18 64.8 2.3 7.2e-18 64.2 2.3 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) DUF523 PF04463.12 CRK39537.1 - 0.0017 18.4 0.2 0.002 18.2 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF523) CpXC PF14353.6 CRK39537.1 - 0.063 13.3 0.2 0.093 12.8 0.2 1.4 1 0 0 1 1 1 0 CpXC protein HEAT_2 PF13646.6 CRK39539.1 - 1.6e-13 50.8 1.5 4.7e-12 46.1 0.4 2.8 2 1 1 3 3 3 1 HEAT repeats HEAT_PBS PF03130.16 CRK39539.1 - 1.9e-09 37.3 8.2 0.028 15.1 0.5 5.0 5 1 0 5 5 5 3 PBS lyase HEAT-like repeat HEAT PF02985.22 CRK39539.1 - 0.0046 17.1 2.1 0.61 10.5 0.0 3.5 4 0 0 4 4 4 1 HEAT repeat Arm PF00514.23 CRK39539.1 - 0.088 12.9 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 CRK39539.1 - 0.19 12.3 0.9 31 5.2 0.1 3.1 3 0 0 3 3 3 0 HEAT-like repeat Ras PF00071.22 CRK39543.1 - 1.5e-59 200.3 0.2 1.7e-59 200.0 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CRK39543.1 - 1.8e-20 73.4 0.0 2.7e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CRK39543.1 - 3.1e-08 33.3 0.0 3.4e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CRK39543.1 - 6e-06 25.9 0.1 4.2e-05 23.2 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CRK39543.1 - 0.00018 21.5 0.4 0.68 9.8 0.0 2.4 1 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 CRK39543.1 - 0.0017 18.4 0.0 0.0026 17.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 CRK39543.1 - 0.0049 16.9 0.0 0.0094 16.0 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain FeoB_N PF02421.18 CRK39543.1 - 0.005 16.4 0.0 0.0093 15.5 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B ATP_bind_1 PF03029.17 CRK39543.1 - 0.15 11.8 1.3 2.1 8.0 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Pput2613-deam PF14427.6 CRK39545.1 - 4.5 7.2 5.2 30 4.5 0.3 3.3 2 0 0 2 2 2 0 Pput_2613-like deaminase Zn_clus PF00172.18 CRK39545.1 - 4.9 7.4 162.5 0.015 15.4 6.3 16.5 18 2 1 19 19 19 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Kelch_5 PF13854.6 CRK39549.1 - 4.3e-11 42.5 1.1 1.9e-10 40.5 0.2 2.8 2 0 0 2 2 2 1 Kelch motif Kelch_3 PF13415.6 CRK39549.1 - 3.7e-06 27.1 0.5 0.0061 16.8 0.1 3.4 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_4 PF13418.6 CRK39549.1 - 3e-05 24.0 1.0 0.78 9.8 0.0 4.1 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.25 CRK39549.1 - 8.7e-05 22.0 3.0 0.6 9.7 0.3 4.2 3 1 0 3 3 3 2 Kelch motif Kelch_6 PF13964.6 CRK39549.1 - 0.0039 17.4 5.3 0.18 12.2 0.0 4.0 4 1 0 4 4 4 1 Kelch motif LST1 PF05083.13 CRK39549.1 - 0.039 14.2 0.0 0.12 12.6 0.0 1.9 2 0 0 2 2 2 0 LST-1 protein F-box-like PF12937.7 CRK39551.1 - 0.00029 20.7 2.7 0.5 10.3 0.2 2.9 2 1 0 2 2 2 2 F-box-like DUF2259 PF10016.9 CRK39551.1 - 0.09 12.7 0.2 9.1 6.2 0.0 2.3 2 0 0 2 2 2 0 Predicted secreted protein (DUF2259) APC_N_CC PF16689.5 CRK39551.1 - 0.095 12.8 0.7 6.5 6.9 0.0 2.4 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain DUF3526 PF12040.8 CRK39552.1 - 0.11 12.9 0.1 0.15 12.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3526) FliO PF04347.13 CRK39552.1 - 0.18 12.1 1.0 3 8.2 0.6 2.2 1 1 1 2 2 2 0 Flagellar biosynthesis protein, FliO Pyrid_ox_like PF16242.5 CRK39553.1 - 4e-23 81.7 0.1 5.9e-23 81.1 0.1 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 CRK39553.1 - 1.7e-10 41.0 0.0 6.7e-10 39.0 0.0 1.8 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase FMN_bind_2 PF04299.12 CRK39553.1 - 0.017 14.8 0.0 0.026 14.2 0.0 1.3 1 0 0 1 1 1 0 Putative FMN-binding domain DUF1449 PF07290.11 CRK39553.1 - 0.13 11.9 0.1 0.22 11.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1449) Pyrid_ox_like PF16242.5 CRK39554.1 - 8.2e-17 61.2 0.0 1.3e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 CRK39554.1 - 1.1e-07 31.9 0.0 1.7e-06 28.2 0.0 2.1 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase DUF1449 PF07290.11 CRK39554.1 - 0.068 12.8 0.1 0.1 12.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1449) TP_methylase PF00590.20 CRK39555.1 - 5.3e-29 101.7 0.8 2e-13 50.8 0.0 2.4 1 1 1 2 2 2 2 Tetrapyrrole (Corrin/Porphyrin) Methylases HET PF06985.11 CRK39556.1 - 1.2e-29 103.6 0.0 1.7e-29 103.1 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) UQ_con PF00179.26 CRK39557.1 - 3.7e-35 120.6 0.0 4.3e-35 120.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CRK39557.1 - 0.014 15.1 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B NmrA PF05368.13 CRK39559.1 - 4.9e-35 121.2 0.0 9e-35 120.3 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 CRK39559.1 - 1.2e-12 48.1 0.0 1.7e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 CRK39559.1 - 0.00074 19.0 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 CRK39559.1 - 0.00098 19.4 0.1 0.0039 17.4 0.0 2.0 2 0 0 2 2 2 1 TrkA-N domain LytR_C PF13399.6 CRK39559.1 - 0.0053 17.7 0.5 0.73 10.9 0.0 2.3 2 0 0 2 2 2 1 LytR cell envelope-related transcriptional attenuator F420_oxidored PF03807.17 CRK39559.1 - 0.013 16.0 0.1 0.027 15.1 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent adh_short_C2 PF13561.6 CRK39559.1 - 0.026 14.1 0.7 5 6.6 0.4 2.3 1 1 1 2 2 2 0 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRK39559.1 - 0.035 13.6 0.1 0.11 12.0 0.1 1.8 2 0 0 2 2 2 0 short chain dehydrogenase Semialdhyde_dh PF01118.24 CRK39559.1 - 0.16 12.4 0.1 1.4 9.4 0.0 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Glyco_hydro_35 PF01301.19 CRK39560.1 - 2.5e-152 507.0 9.1 1.2e-83 281.4 0.5 3.4 2 1 1 3 3 3 3 Glycosyl hydrolases family 35 Glyco_hydro_43 PF04616.14 CRK39560.1 - 8.7e-148 491.3 5.8 1.4e-73 247.8 0.6 2.5 2 0 0 2 2 2 2 Glycosyl hydrolases family 43 Lyase_1 PF00206.20 CRK39560.1 - 2.4e-141 470.6 0.0 2.5e-86 289.9 0.0 2.3 2 0 0 2 2 2 2 Lyase BetaGal_dom4_5 PF13364.6 CRK39560.1 - 1.7e-114 376.6 7.7 1.4e-31 109.4 0.0 4.7 4 0 0 4 4 4 4 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 CRK39560.1 - 2.7e-114 379.3 19.8 3.9e-60 202.8 6.3 2.4 2 0 0 2 2 2 2 Beta-galactosidase, domain 2 ASL_C2 PF14698.6 CRK39560.1 - 9.8e-51 170.4 0.6 7.3e-24 84.3 0.0 3.2 3 0 0 3 3 2 2 Argininosuccinate lyase C-terminal GH43_C2 PF17851.1 CRK39560.1 - 6.6e-45 153.3 0.1 4.9e-21 75.4 0.0 4.1 4 0 0 4 4 4 2 Beta xylosidase C-terminal Concanavalin A-like domain BetaGal_dom3 PF13363.6 CRK39560.1 - 3.3e-44 148.3 0.1 1.3e-20 72.7 0.0 2.9 2 0 0 2 2 2 2 Beta-galactosidase, domain 3 HET PF06985.11 CRK39560.1 - 3.2e-28 98.9 0.0 7.2e-28 97.8 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NmrA PF05368.13 CRK39560.1 - 1.2e-25 90.4 0.0 2.2e-25 89.6 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 CRK39560.1 - 1.1e-07 31.9 0.1 2.2e-07 30.9 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Glyco_hydro_62 PF03664.13 CRK39560.1 - 1.6e-06 27.7 0.0 0.07 12.4 0.0 2.6 2 0 0 2 2 2 2 Glycosyl hydrolase family 62 TP_methylase PF00590.20 CRK39560.1 - 0.0018 18.2 0.0 0.0059 16.6 0.0 1.9 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF1471 PF07338.13 CRK39560.1 - 0.1 12.6 0.1 30 4.7 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1471) OTOS PF15182.6 CRK39560.1 - 0.21 11.5 5.4 3.5 7.6 0.5 2.9 2 0 0 2 2 2 0 Otospiralin Cytochrom_C_2 PF01322.20 CRK39560.1 - 0.25 12.2 3.1 0.79 10.6 3.1 1.8 1 0 0 1 1 1 0 Cytochrome C' Atg14 PF10186.9 CRK39560.1 - 0.34 9.9 5.4 0.25 10.4 3.8 1.4 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Methyltransf_23 PF13489.6 CRK39562.1 - 6e-20 71.7 0.0 1.2e-19 70.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK39562.1 - 9.7e-13 48.6 0.0 2.7e-12 47.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK39562.1 - 8e-10 38.7 0.0 2e-08 34.2 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CRK39562.1 - 4.5e-08 33.6 0.0 1.1e-07 32.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK39562.1 - 1.2e-07 32.3 0.0 6.5e-07 30.0 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain zf-C2H2_jaz PF12171.8 CRK39562.1 - 1.2e-06 28.6 0.3 1.2e-06 28.6 0.3 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding SNRNP27 PF08648.12 CRK39562.1 - 0.00011 22.2 0.1 0.0003 20.8 0.1 1.7 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins zf-met PF12874.7 CRK39562.1 - 0.00013 22.3 0.3 0.00013 22.3 0.3 2.1 2 0 0 2 2 2 1 Zinc-finger of C2H2 type MTS PF05175.14 CRK39562.1 - 0.00076 19.1 0.0 0.0015 18.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain DUF4586 PF15239.6 CRK39562.1 - 0.0026 18.0 0.2 0.0078 16.4 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4586) Methyltransf_4 PF02390.17 CRK39562.1 - 0.0054 16.2 0.3 0.017 14.6 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase zf-DBF PF07535.12 CRK39562.1 - 0.0072 16.4 1.6 0.021 14.9 0.1 2.3 2 0 0 2 2 2 1 DBF zinc finger Methyltransf_16 PF10294.9 CRK39562.1 - 0.0074 16.0 0.0 0.39 10.4 0.0 2.4 2 0 0 2 2 2 1 Lysine methyltransferase PrmA PF06325.13 CRK39562.1 - 0.016 14.6 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) zf-C2H2 PF00096.26 CRK39562.1 - 0.022 15.2 0.5 0.022 15.2 0.5 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type FtsJ PF01728.19 CRK39562.1 - 0.032 14.3 0.0 0.063 13.4 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase zf-C2H2_2 PF12756.7 CRK39562.1 - 0.034 14.5 0.8 0.29 11.5 0.0 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 CRK39562.1 - 0.13 13.1 0.1 0.46 11.4 0.1 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger Methyltransf_23 PF13489.6 CRK39563.1 - 1.9e-20 73.4 0.0 2.9e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK39563.1 - 5.7e-13 49.4 0.0 1.3e-12 48.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK39563.1 - 6.6e-10 39.0 0.0 1.7e-05 24.6 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 CRK39563.1 - 2e-08 34.8 0.0 3.4e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK39563.1 - 1.1e-07 32.5 0.0 4.7e-07 30.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CRK39563.1 - 0.0018 17.8 0.0 0.0032 17.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 CRK39563.1 - 0.016 14.6 0.0 0.04 13.4 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase PrmA PF06325.13 CRK39563.1 - 0.025 14.0 0.0 0.039 13.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 CRK39563.1 - 0.042 14.0 0.0 0.066 13.3 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase DUF4276 PF14103.6 CRK39563.1 - 0.08 13.2 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4276) Pkinase PF00069.25 CRK39564.1 - 1.1e-34 120.0 0.0 1.3e-34 119.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK39564.1 - 4.2e-11 42.6 0.0 6e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CRK39564.1 - 0.0085 14.9 0.0 0.012 14.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CRK39564.1 - 0.018 14.9 0.0 0.64 9.9 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 CRK39564.1 - 0.033 13.5 0.0 0.054 12.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-RING_2 PF13639.6 CRK39565.1 - 1.3e-08 35.0 9.1 2.4e-08 34.1 9.1 1.5 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 CRK39565.1 - 1.2e-05 25.4 9.0 3.4e-05 23.9 9.0 1.8 1 1 0 1 1 1 1 FANCL C-terminal domain zf-ANAPC11 PF12861.7 CRK39565.1 - 8.1e-05 22.6 2.3 0.00019 21.4 2.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 CRK39565.1 - 0.00016 21.9 8.0 0.00039 20.6 8.0 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CRK39565.1 - 0.002 18.0 10.9 0.0036 17.1 10.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 CRK39565.1 - 0.0033 17.5 8.1 0.0068 16.5 8.1 1.6 1 0 0 1 1 1 1 RING-variant domain C1_1 PF00130.22 CRK39565.1 - 0.004 17.0 3.5 0.004 17.0 3.5 1.7 1 1 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn_ribbon_17 PF17120.5 CRK39565.1 - 0.024 14.2 5.6 0.058 13.0 5.6 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 CRK39565.1 - 0.039 13.8 5.9 0.079 12.8 5.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CRK39565.1 - 0.067 13.1 9.2 0.13 12.1 9.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 CRK39565.1 - 0.17 12.2 8.3 0.33 11.3 8.3 1.5 1 0 0 1 1 1 0 RING-like domain zf-RING_9 PF13901.6 CRK39565.1 - 0.91 9.5 6.8 1.9 8.4 6.8 1.5 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon Prok-RING_4 PF14447.6 CRK39565.1 - 1 9.3 6.8 3 7.8 6.9 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 CRK39565.1 - 1.5 8.9 6.3 3.3 7.8 6.3 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Zf_RING PF16744.5 CRK39565.1 - 1.9 8.7 6.6 7.5 6.7 3.9 2.6 2 0 0 2 2 2 0 KIAA1045 RING finger PHD PF00628.29 CRK39565.1 - 2.9 7.9 7.8 5.6 6.9 7.8 1.5 1 0 0 1 1 1 0 PHD-finger DUF3439 PF11921.8 CRK39566.1 - 0.13 12.2 0.2 0.39 10.7 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) PEGSRP PF07623.11 CRK39566.1 - 2.8 7.8 4.3 7.6 6.5 1.0 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1584) VHP PF02209.19 CRK39567.1 - 0.12 12.5 1.3 0.15 12.1 1.3 1.2 1 0 0 1 1 1 0 Villin headpiece domain Ribosomal_L1 PF00687.21 CRK39569.1 - 1.6e-62 210.9 1.1 2.7e-62 210.1 1.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Palm_thioest PF02089.15 CRK39571.1 - 1.3e-77 260.9 0.0 1.5e-77 260.7 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Lipase_2 PF01674.18 CRK39571.1 - 0.0099 15.4 0.0 0.017 14.7 0.0 1.5 1 1 0 1 1 1 1 Lipase (class 2) DUF915 PF06028.11 CRK39571.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Cyclin_N PF00134.23 CRK39572.1 - 2.1e-08 34.0 0.2 4.7e-08 32.8 0.2 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain NAD_binding_4 PF07993.12 CRK39572.1 - 0.052 12.7 0.0 0.095 11.8 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein Glyco_transf_28 PF03033.20 CRK39573.1 - 1.4e-23 83.5 0.0 2.8e-23 82.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 CRK39573.1 - 6.9e-06 25.1 0.0 1.1e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 CRK39573.1 - 0.023 14.7 0.0 0.039 13.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain FMN_dh PF01070.18 CRK39575.1 - 6.2e-27 94.5 0.1 5.2e-26 91.5 0.0 1.9 1 1 1 2 2 2 2 FMN-dependent dehydrogenase dsrm PF00035.26 CRK39580.1 - 0.00063 20.4 0.0 0.0013 19.3 0.0 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.6 CRK39580.1 - 0.018 15.2 0.1 0.046 13.9 0.1 1.7 2 0 0 2 2 2 0 Ribonuclease-III-like PLA2_B PF01735.18 CRK39582.1 - 2.8e-28 98.6 0.0 4.6e-28 97.9 0.0 1.3 1 0 0 1 1 1 1 Lysophospholipase catalytic domain FMO-like PF00743.19 CRK39583.1 - 8e-60 202.8 0.0 1e-59 202.4 0.0 1.1 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 CRK39583.1 - 4.1e-22 78.8 0.0 1.7e-18 66.9 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CRK39583.1 - 7.3e-16 58.2 0.0 8.8e-14 51.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CRK39583.1 - 9.5e-10 38.9 0.1 0.00027 21.5 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CRK39583.1 - 9.7e-07 28.9 0.0 3.2e-06 27.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 CRK39583.1 - 1.3e-06 27.8 0.1 5e-05 22.6 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 CRK39583.1 - 3.9e-06 26.7 0.7 0.0062 16.2 0.6 3.1 2 1 1 3 3 3 1 FAD dependent oxidoreductase IlvN PF07991.12 CRK39583.1 - 7e-06 25.7 0.0 0.17 11.5 0.0 2.8 3 0 0 3 3 3 2 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_7 PF13241.6 CRK39583.1 - 0.0008 19.8 0.0 1.4 9.4 0.0 3.0 2 1 0 2 2 2 2 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 CRK39583.1 - 0.0025 17.2 0.0 0.006 15.9 0.0 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 CRK39583.1 - 0.0031 16.8 0.1 0.0057 15.9 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 CRK39583.1 - 0.0065 16.5 0.3 0.62 10.0 0.0 2.9 3 0 0 3 3 2 1 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.19 CRK39583.1 - 0.008 15.6 0.0 0.49 9.7 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.14 CRK39583.1 - 0.017 13.8 0.1 0.03 13.0 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.17 CRK39583.1 - 0.027 13.7 0.3 0.32 10.2 0.1 2.5 3 0 0 3 3 3 0 Thi4 family Shikimate_DH PF01488.20 CRK39583.1 - 0.028 14.5 0.0 13 5.8 0.0 2.8 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase SnoaL_4 PF13577.6 CRK39583.1 - 0.037 14.2 0.0 0.091 12.9 0.0 1.7 1 0 0 1 1 1 0 SnoaL-like domain Amino_oxidase PF01593.24 CRK39583.1 - 0.049 12.9 0.0 0.089 12.1 0.0 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Septin PF00735.18 CRK39586.1 - 9.7e-118 392.5 0.1 9.7e-118 392.5 0.1 1.7 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 CRK39586.1 - 4.3e-08 33.2 0.9 9.1e-08 32.2 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CRK39586.1 - 7.9e-05 22.3 0.8 0.0012 18.4 0.0 2.7 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CRK39586.1 - 0.0001 22.3 2.6 0.0038 17.2 0.8 3.2 2 1 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 CRK39586.1 - 0.00016 22.2 0.8 0.036 14.6 0.0 2.5 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 CRK39586.1 - 0.0019 18.6 0.1 0.0077 16.6 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CRK39586.1 - 0.0021 18.3 0.0 0.049 13.9 0.0 2.9 3 1 0 3 3 3 1 AAA domain Roc PF08477.13 CRK39586.1 - 0.0029 17.8 0.0 0.0067 16.6 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 CRK39586.1 - 0.0041 16.5 1.9 0.0061 15.9 0.0 2.1 2 0 0 2 2 2 1 AIG1 family Ras PF00071.22 CRK39586.1 - 0.015 14.9 0.1 0.06 12.9 0.0 2.1 2 0 0 2 2 2 0 Ras family AAA_29 PF13555.6 CRK39586.1 - 0.018 14.8 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 CRK39586.1 - 0.073 12.4 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_24 PF13479.6 CRK39586.1 - 0.091 12.5 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CRK39586.1 - 0.11 12.9 0.7 0.8 10.1 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_7 PF12775.7 CRK39586.1 - 0.13 11.8 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Dynamin_N PF00350.23 CRK39586.1 - 0.57 10.2 9.6 1.2 9.2 0.0 3.4 3 1 0 3 3 2 0 Dynamin family Exonuc_VII_L PF02601.15 CRK39586.1 - 0.66 9.5 7.8 1.2 8.6 7.8 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit AP1AR PF15745.5 CRK39586.1 - 0.82 9.3 9.2 1.7 8.2 9.2 1.4 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein TSNAXIP1_N PF15739.5 CRK39586.1 - 1.2 9.6 14.1 8.7 6.8 0.0 2.6 2 1 1 3 3 3 0 Translin-associated factor X-interacting N-terminus Caldesmon PF02029.15 CRK39586.1 - 1.3 7.7 19.4 2 7.1 19.4 1.2 1 0 0 1 1 1 0 Caldesmon MSA-2c PF12238.8 CRK39586.1 - 2.5 8.0 5.5 6.1 6.8 5.5 1.6 1 0 0 1 1 1 0 Merozoite surface antigen 2c Atg14 PF10186.9 CRK39586.1 - 4.8 6.2 7.8 7.4 5.6 7.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 S4 PF01479.25 CRK39588.1 - 2.7e-12 46.2 0.1 1.5e-11 43.9 0.0 2.4 2 0 0 2 2 2 1 S4 domain YCII PF03795.14 CRK39588.1 - 0.22 12.0 3.2 0.61 10.5 3.2 1.8 1 0 0 1 1 1 0 YCII-related domain RBM39linker PF15519.6 CRK39588.1 - 4.7 8.4 8.2 9.6 7.4 1.4 2.8 2 1 0 2 2 2 0 linker between RRM2 and RRM3 domains in RBM39 protein Spore_coat_CotO PF14153.6 CRK39588.1 - 7.3 6.5 10.6 2.3 8.1 5.4 2.1 2 0 0 2 2 2 0 Spore coat protein CotO MFS_1 PF07690.16 CRK39589.1 - 3.7e-37 128.1 28.2 4.4e-37 127.8 28.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily La PF05383.17 CRK39589.1 - 1e-14 54.3 0.0 1.8e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 La domain Sugar_tr PF00083.24 CRK39589.1 - 6.7e-08 31.8 4.8 1.2e-07 31.0 4.8 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter RRM_1 PF00076.22 CRK39589.1 - 5.4e-06 26.1 0.2 9.4e-06 25.4 0.2 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TRI12 PF06609.13 CRK39589.1 - 0.00033 19.2 1.8 0.00048 18.7 1.8 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Big_9 PF17963.1 CRK39591.1 - 9.2 7.1 9.0 3.8 8.3 0.1 3.9 2 1 0 2 2 2 0 Bacterial Ig domain DUF898 PF05987.13 CRK39593.1 - 0.011 14.8 3.1 0.015 14.4 3.1 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) DUF3995 PF13160.6 CRK39593.1 - 0.022 15.1 0.5 0.022 15.1 0.5 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3995) MgtE PF01769.16 CRK39593.1 - 0.026 14.9 8.5 0.15 12.4 8.7 1.9 1 1 0 1 1 1 0 Divalent cation transporter FtsX PF02687.21 CRK39593.1 - 0.032 14.7 1.0 0.032 14.7 1.0 2.3 2 1 0 2 2 2 0 FtsX-like permease family DUF2976 PF11190.8 CRK39593.1 - 0.058 13.2 5.4 0.081 12.7 2.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2976) TctB PF07331.11 CRK39593.1 - 0.14 12.4 6.6 0.63 10.3 6.6 2.0 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family DUF2207 PF09972.9 CRK39593.1 - 0.21 10.3 2.5 1.4 7.6 2.5 2.0 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) TauE PF01925.19 CRK39593.1 - 0.54 9.9 9.7 1.2 8.8 4.0 2.1 1 1 1 2 2 2 0 Sulfite exporter TauE/SafE FA_desaturase PF00487.24 CRK39593.1 - 0.76 9.6 7.0 0.073 12.9 2.7 1.5 2 0 0 2 2 2 0 Fatty acid desaturase DUF4131 PF13567.6 CRK39593.1 - 1.3 8.6 7.5 6.2 6.4 0.3 2.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) Tetraspanin PF00335.20 CRK39593.1 - 1.5 8.5 4.9 1.3 8.7 2.6 1.9 2 0 0 2 2 2 0 Tetraspanin family MFS_1 PF07690.16 CRK39593.1 - 1.9 7.3 11.7 0.19 10.6 3.9 2.3 1 1 1 2 2 2 0 Major Facilitator Superfamily TRIC PF05197.13 CRK39597.1 - 0.11 12.1 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 TRIC channel Peptidase_M35 PF02102.15 CRK39599.1 - 3e-56 190.8 1.4 4e-56 190.4 1.4 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 CRK39599.1 - 2.5e-34 118.9 0.2 4.1e-34 118.2 0.2 1.3 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.6 CRK39599.1 - 0.0013 18.3 0.3 0.0029 17.2 0.3 1.4 1 1 0 1 1 1 1 Putative peptidase family PAP2 PF01569.21 CRK39604.1 - 0.0014 18.4 0.8 0.013 15.2 0.1 2.0 2 0 0 2 2 2 1 PAP2 superfamily DUF983 PF06170.12 CRK39604.1 - 0.29 11.6 2.7 0.33 11.4 2.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF983) ABC_tran PF00005.27 CRK39609.1 - 1.9e-10 41.4 0.0 2.1e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 ABC transporter DUF2336 PF10098.9 CRK39609.1 - 0.057 12.9 0.0 0.071 12.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2336) Ribosomal_L15e PF00827.17 CRK39611.1 - 6.7e-86 286.9 10.2 1e-85 286.3 10.2 1.2 1 0 0 1 1 1 1 Ribosomal L15 CFIA_Pcf11 PF11526.8 CRK39611.1 - 6.2e-06 26.6 1.3 1.7e-05 25.2 0.0 2.3 2 0 0 2 2 2 1 Subunit of cleavage factor IA Pcf11 zf-C2H2_4 PF13894.6 CRK39611.1 - 0.28 12.2 3.8 8.2 7.6 0.9 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-RRN7 PF11781.8 CRK39611.1 - 0.34 10.6 2.0 0.32 10.7 0.2 1.9 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Prok-RING_1 PF14446.6 CRK39611.1 - 0.45 10.5 1.6 31 4.6 0.1 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Epimerase PF01370.21 CRK39618.1 - 1.4e-16 60.7 0.0 2.3e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CRK39618.1 - 9.5e-10 37.9 0.0 1.7e-09 37.1 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 CRK39618.1 - 1.5e-09 37.4 0.0 5.6e-07 29.0 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 CRK39618.1 - 8.3e-07 28.7 0.1 1.2e-06 28.1 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 CRK39618.1 - 5.1e-06 26.5 0.0 9.8e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 CRK39618.1 - 0.0003 20.4 0.0 0.00058 19.5 0.0 1.5 2 0 0 2 2 2 1 NmrA-like family KR PF08659.10 CRK39618.1 - 0.015 15.2 0.2 0.047 13.6 0.2 1.8 1 1 0 1 1 1 0 KR domain adh_short PF00106.25 CRK39618.1 - 0.048 13.1 0.0 0.12 11.8 0.0 1.7 1 1 0 1 1 1 0 short chain dehydrogenase Glyco_hydro_28 PF00295.17 CRK39620.1 - 1.1e-46 159.4 5.7 1.6e-46 158.9 5.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Glyco_hydro_28 PF00295.17 CRK39622.1 - 2.9e-51 174.5 18.0 3.8e-51 174.1 18.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 SMYLE_N PF18615.1 CRK39623.1 - 0.0063 16.1 0.0 0.0081 15.8 0.0 1.1 1 0 0 1 1 1 1 Short myomegalin-like EB1 binding proteins, N-terminal domain His_Phos_1 PF00300.22 CRK39623.1 - 0.012 15.3 1.4 0.39 10.4 0.0 2.5 1 1 1 2 2 2 0 Histidine phosphatase superfamily (branch 1) Chromadorea_ALT PF05535.12 CRK39623.1 - 0.1 12.8 0.3 5.6 7.2 0.0 2.3 2 0 0 2 2 2 0 Chromadorea ALT protein PapJ PF14855.6 CRK39623.1 - 0.18 11.4 0.0 0.27 10.9 0.0 1.2 1 0 0 1 1 1 0 Pilus-assembly fibrillin subunit, chaperone Oxysterol_BP PF01237.18 CRK39629.1 - 1.1e-19 70.6 0.0 1.2e-19 70.5 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein TMEM135_C_rich PF15982.5 CRK39631.1 - 6.8e-05 23.5 0.5 0.00023 21.8 0.2 1.9 2 1 0 2 2 2 1 N-terminal cysteine-rich region of Transmembrane protein 135 DUF3177 PF11375.8 CRK39631.1 - 0.092 12.5 0.1 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3177) Gp_dh_C PF02800.20 CRK39633.1 - 1e-71 239.6 0.5 1.5e-71 239.1 0.5 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 CRK39633.1 - 3.7e-19 68.9 0.0 1.2e-18 67.3 0.0 1.9 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain NADH_u_ox_C PF12853.7 CRK39637.1 - 2.7e-26 91.4 0.0 2.9e-26 91.3 0.0 1.0 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit DUF4440 PF14534.6 CRK39648.1 - 1.4e-05 25.4 0.1 1.7e-05 25.1 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SR-25 PF10500.9 CRK39649.1 - 4.4e-06 26.5 10.0 5.2e-06 26.2 10.0 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Dehydrin PF00257.19 CRK39649.1 - 1.5e-05 25.7 5.4 2.2e-05 25.1 5.4 1.3 1 0 0 1 1 1 1 Dehydrin Glyco_hydro_28 PF00295.17 CRK39649.1 - 0.028 13.5 0.0 0.035 13.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 28 DUF755 PF05501.11 CRK39649.1 - 0.045 14.0 20.9 0.076 13.3 20.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Chorion_2 PF03964.15 CRK39649.1 - 0.059 14.2 6.4 0.096 13.5 6.4 1.4 1 0 0 1 1 1 0 Chorion family 2 Apt1 PF10351.9 CRK39649.1 - 0.34 9.7 7.2 0.39 9.5 7.2 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 CRK39649.1 - 0.76 8.3 6.2 0.9 8.0 6.2 1.0 1 0 0 1 1 1 0 Macoilin family CENP-U PF13097.6 CRK39649.1 - 1.9 8.4 11.1 2.4 8.1 11.1 1.2 1 0 0 1 1 1 0 CENP-A nucleosome associated complex (NAC) subunit DUF4603 PF15376.6 CRK39649.1 - 2.3 5.5 10.3 2.8 5.2 10.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) DUF3446 PF11928.8 CRK39649.1 - 4 7.8 12.3 0.97 9.8 7.4 2.1 2 0 0 2 2 2 0 Early growth response N-terminal domain CCDC106 PF15794.5 CRK39649.1 - 4.7 6.8 9.7 6.4 6.4 9.7 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Lin-8 PF03353.15 CRK39649.1 - 7.7 6.0 9.4 10 5.6 9.4 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist GREB1 PF15782.5 CRK39649.1 - 9.2 3.2 7.7 11 2.9 7.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Sugar_tr PF00083.24 CRK39653.1 - 8.7e-08 31.4 3.4 8.9e-08 31.4 3.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Phage_holin_2_4 PF16082.5 CRK39653.1 - 1.5 8.6 3.7 0.46 10.3 0.5 1.9 1 1 2 3 3 3 0 Bacteriophage holin family, superfamily II-like DUF4200 PF13863.6 CRK39668.1 - 0.023 15.1 0.0 0.028 14.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DUF4707 PF15806.5 CRK39668.1 - 0.075 12.0 0.0 0.082 11.8 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4707) Acyl-CoA_dh_1 PF00441.24 CRK39670.1 - 2.2e-26 92.9 0.2 3.6e-26 92.2 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 CRK39670.1 - 8.3e-21 74.0 0.0 1.5e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 CRK39670.1 - 4.9e-14 52.9 0.0 1.1e-13 51.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 CRK39670.1 - 2.4e-11 44.0 0.2 4.7e-11 43.1 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DnaJ PF00226.31 CRK39672.1 - 3.1e-08 33.6 0.0 4.5e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain OapA_N PF08525.11 CRK39673.1 - 0.63 10.0 7.5 4.4 7.4 0.3 2.4 2 0 0 2 2 2 0 Opacity-associated protein A N-terminal motif FAD_binding_4 PF01565.23 CRK39678.1 - 3.6e-24 85.1 0.4 7.5e-24 84.0 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 CRK39678.1 - 0.0037 16.9 0.1 0.092 12.4 0.0 2.2 1 1 0 2 2 2 1 FAD linked oxidases, C-terminal domain BBE PF08031.12 CRK39678.1 - 0.048 13.8 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Berberine and berberine like DUF2227 PF09988.9 CRK39678.1 - 0.21 11.4 0.1 0.38 10.6 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized metal-binding protein (DUF2227) EFP_N PF08207.12 CRK39686.1 - 0.00012 22.0 0.0 0.00014 21.8 0.0 1.1 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain PCMD PF13201.6 CRK39686.1 - 0.041 13.7 0.0 0.042 13.6 0.0 1.0 1 0 0 1 1 1 0 Putative carbohydrate metabolism domain ketoacyl-synt PF00109.26 CRK39709.1 - 4e-73 246.1 0.0 8.5e-73 245.0 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 CRK39709.1 - 7.3e-44 150.6 0.3 1.6e-43 149.5 0.3 1.5 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 CRK39709.1 - 2.3e-43 148.2 0.8 6e-43 146.8 0.8 1.8 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 CRK39709.1 - 1.8e-41 142.3 5.9 1.8e-41 142.3 5.9 1.8 2 0 0 2 2 2 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 CRK39709.1 - 1.4e-31 109.0 0.0 1.3e-30 105.8 0.0 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 CRK39709.1 - 3.8e-15 56.3 0.0 8.1e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 CRK39709.1 - 6.4e-11 42.1 0.1 1.3e-10 41.1 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Thiolase_N PF00108.23 CRK39709.1 - 2.4e-05 23.8 0.0 4.9e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain PP-binding PF00550.25 CRK39709.1 - 0.00011 22.5 0.0 0.00025 21.3 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_zinc_N PF00107.26 CRK39711.1 - 1e-08 35.2 0.1 1.8e-08 34.4 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CRK39711.1 - 1.5e-07 31.3 0.1 9.4e-07 28.7 0.1 2.2 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 CRK39711.1 - 0.05 13.5 0.0 0.098 12.6 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase PEX11 PF05648.14 CRK39720.1 - 0.085 12.3 0.0 0.085 12.3 0.0 1.0 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) AtuA PF07287.11 CRK39736.1 - 2.3e-85 286.4 0.0 3e-85 286.0 0.0 1.2 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA MFS_1 PF07690.16 CRK39736.1 - 2.9e-06 26.4 16.7 2.9e-06 26.4 16.7 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Aldedh PF00171.22 CRK39738.1 - 3.2e-166 553.4 0.4 3.9e-166 553.1 0.4 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family FMO-like PF00743.19 CRK39739.1 - 2e-15 56.3 0.3 8.5e-11 41.0 0.1 2.6 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 CRK39739.1 - 2.2e-09 37.0 0.0 2.5e-06 27.0 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CRK39739.1 - 4.4e-09 36.0 0.1 1.8e-07 30.7 0.1 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CRK39739.1 - 7.1e-09 35.8 0.0 2.5e-08 34.0 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CRK39739.1 - 4.6e-07 29.7 0.5 0.003 17.2 0.2 3.1 1 1 1 3 3 3 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 CRK39739.1 - 4.8e-06 25.9 0.1 0.00011 21.5 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 CRK39739.1 - 0.014 15.4 0.7 3.1 7.8 0.1 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding Sod_Fe_C PF02777.18 CRK39745.1 - 5e-08 33.0 0.0 6.3e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 CRK39745.1 - 4.9e-06 26.9 0.1 6.8e-06 26.5 0.1 1.2 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain HAUS6_N PF14661.6 CRK39752.1 - 1.3e-08 34.7 0.0 1.3e-08 34.7 0.0 1.0 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus PAP2_3 PF14378.6 CRK39756.1 - 0.00055 19.7 0.0 0.00055 19.7 0.0 1.1 1 0 0 1 1 1 1 PAP2 superfamily GTP_EFTU PF00009.27 CRK39769.1 - 2.9e-52 177.0 0.2 3.5e-52 176.8 0.2 1.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CRK39769.1 - 7.3e-05 22.8 0.2 0.0011 19.0 0.2 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase COP-gamma_platf PF08752.10 CRK39772.1 - 2.9e-55 186.6 5.9 6.2e-55 185.5 5.9 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 CRK39772.1 - 6.3e-37 126.2 0.1 1.4e-36 125.1 0.1 1.6 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform Adaptin_N PF01602.20 CRK39772.1 - 1.5e-31 109.6 1.1 1.8e-30 106.1 1.1 1.9 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CRK39772.1 - 2.6e-06 27.6 2.7 1.9e-05 24.8 0.8 2.4 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 CRK39772.1 - 1.5e-05 24.7 0.2 2.7e-05 23.8 0.2 1.3 1 0 0 1 1 1 1 CLASP N terminal HEAT_2 PF13646.6 CRK39772.1 - 7.8e-05 23.0 0.5 0.00017 21.9 0.5 1.6 1 0 0 1 1 1 1 HEAT repeats DUF5010 PF16402.5 CRK39772.1 - 0.016 14.1 0.0 0.08 11.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5010) Coatomer_b_Cpla PF14806.6 CRK39772.1 - 0.028 14.4 0.0 0.071 13.1 0.0 1.7 1 0 0 1 1 1 0 Coatomer beta subunit appendage platform HEAT PF02985.22 CRK39772.1 - 1.1 9.7 6.6 1.2 9.6 0.4 3.7 4 1 1 5 5 5 0 HEAT repeat CDP-OH_P_transf PF01066.21 CRK39774.1 - 8.8e-17 61.6 0.1 8.8e-17 61.6 0.1 3.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase bZIP_1 PF00170.21 CRK39776.1 - 7.4e-09 35.6 15.0 1.6e-08 34.5 15.0 1.5 1 0 0 1 1 1 1 bZIP transcription factor TFIIA PF03153.13 CRK39776.1 - 1.3e-05 25.4 25.5 1.8e-05 25.0 25.5 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PAP1 PF08601.10 CRK39776.1 - 1.7e-05 24.7 0.0 1.7e-05 24.7 0.0 3.2 1 1 2 3 3 3 1 Transcription factor PAP1 bZIP_Maf PF03131.17 CRK39776.1 - 0.0032 17.9 11.9 0.0032 17.9 11.9 3.3 3 0 0 3 3 3 1 bZIP Maf transcription factor SHE3 PF17078.5 CRK39776.1 - 0.0086 15.8 6.5 0.0086 15.8 6.5 1.7 2 0 0 2 2 2 1 SWI5-dependent HO expression protein 3 YabA PF06156.13 CRK39776.1 - 0.028 15.0 0.1 0.028 15.0 0.1 2.8 2 1 0 2 2 2 0 Initiation control protein YabA DUF812 PF05667.11 CRK39776.1 - 0.15 10.9 17.5 0.21 10.5 17.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) FlaC_arch PF05377.11 CRK39776.1 - 0.21 12.0 1.9 0.48 10.9 1.9 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Macoilin PF09726.9 CRK39776.1 - 0.86 8.1 14.1 1.1 7.7 14.1 1.1 1 0 0 1 1 1 0 Macoilin family Zn_clus PF00172.18 CRK39778.1 - 1.2 9.3 4.1 2 8.6 4.1 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain RRM_1 PF00076.22 CRK39780.1 - 2e-18 66.0 0.0 2.4e-13 49.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CRK39780.1 - 0.028 14.3 0.0 0.17 11.8 0.0 2.0 2 0 0 2 2 2 0 Occluded RNA-recognition motif RRM_Rrp7 PF17799.1 CRK39780.1 - 0.21 11.4 0.0 0.37 10.6 0.0 1.3 1 0 0 1 1 1 0 Rrp7 RRM-like N-terminal domain adh_short PF00106.25 CRK39784.1 - 2.6e-26 92.3 0.0 1.3e-17 63.9 0.0 2.2 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CRK39784.1 - 2.1e-21 76.5 0.2 1.2e-13 51.2 0.2 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK39784.1 - 0.0009 19.2 0.0 0.0014 18.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Ras PF00071.22 CRK39786.1 - 1.9e-51 173.9 0.0 2.3e-51 173.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CRK39786.1 - 2.3e-19 69.7 0.0 3.3e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CRK39786.1 - 1.5e-10 40.8 0.0 1.9e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CRK39786.1 - 9.3e-07 28.6 0.2 7.8e-06 25.6 0.1 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CRK39786.1 - 0.00019 21.4 0.0 0.69 9.8 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 CRK39786.1 - 0.00038 20.5 0.0 0.00056 20.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.6 CRK39786.1 - 0.011 15.9 0.0 0.02 15.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 CRK39786.1 - 0.054 12.7 0.0 0.076 12.2 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.6 CRK39786.1 - 0.078 13.4 0.0 0.26 11.7 0.0 1.9 2 1 0 2 2 2 0 AAA ATPase domain Scytalone_dh PF02982.14 CRK39786.1 - 0.11 12.3 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Scytalone dehydratase adh_short PF00106.25 CRK39787.1 - 2.8e-27 95.5 0.0 4.2e-27 94.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK39787.1 - 1.7e-09 37.6 0.3 3.3e-08 33.4 0.3 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK39787.1 - 4e-06 26.9 0.3 0.0016 18.4 0.0 2.3 2 0 0 2 2 2 2 KR domain NAD_binding_10 PF13460.6 CRK39787.1 - 0.0001 22.2 2.4 0.00039 20.4 0.3 2.2 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 CRK39787.1 - 0.00061 19.3 0.2 0.0022 17.5 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CRK39787.1 - 0.2 11.0 0.0 1.3 8.3 0.0 1.9 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Eno-Rase_NADH_b PF12242.8 CRK39787.1 - 0.84 9.4 0.0 0.84 9.4 0.0 2.2 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase EphA2_TM PF14575.6 CRK39788.1 - 0.38 11.7 4.4 1.9 9.4 4.3 2.3 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF2553 PF10830.8 CRK39788.1 - 6.1 7.7 9.8 0.9 10.4 5.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2553) Ank_2 PF12796.7 CRK39790.1 - 4.1e-15 56.1 3.0 3.5e-05 24.3 0.7 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CRK39790.1 - 1.3e-12 48.0 1.4 0.0011 19.5 0.0 3.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 CRK39790.1 - 6.8e-12 45.3 1.6 0.00017 21.8 0.1 4.6 3 1 1 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 CRK39790.1 - 1.9e-11 43.1 0.5 0.011 16.1 0.1 5.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 CRK39790.1 - 6.4e-10 39.1 3.0 2e-05 24.8 0.2 3.9 3 1 1 4 4 4 3 Ankyrin repeats (many copies) RhoGEF PF00621.20 CRK39790.1 - 5.2e-05 23.6 0.0 0.51 10.6 0.0 2.6 2 0 0 2 2 2 2 RhoGEF domain RapH_N PF18801.1 CRK39790.1 - 0.0076 16.3 0.5 8.5 6.5 0.0 3.0 3 0 0 3 3 2 2 response regulator aspartate phosphatase H, N terminal Syntaxin_2 PF14523.6 CRK39790.1 - 0.013 15.9 1.0 35 4.8 0.0 3.8 3 0 0 3 3 3 0 Syntaxin-like protein Nup88 PF10168.9 CRK39790.1 - 0.042 11.7 1.9 0.12 10.2 1.5 1.7 2 0 0 2 2 2 0 Nuclear pore component ATP-synt_E_2 PF08112.11 CRK39790.1 - 0.049 13.9 0.5 19 5.7 0.1 2.6 2 0 0 2 2 2 0 ATP synthase epsilon subunit TssO PF17561.2 CRK39790.1 - 0.067 13.3 0.4 0.13 12.3 0.4 1.5 1 0 0 1 1 1 0 Type VI secretion system, TssO Mito_fiss_reg PF05308.11 CRK39790.1 - 0.43 10.6 4.9 0.99 9.4 1.9 2.3 2 0 0 2 2 2 0 Mitochondrial fission regulator DUF1690 PF07956.11 CRK39790.1 - 0.66 10.4 14.4 0.9 10.0 4.7 3.9 2 2 1 3 3 3 0 Protein of Unknown function (DUF1690) Aldo_ket_red PF00248.21 CRK39792.1 - 1.7e-40 139.0 0.0 2.1e-40 138.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family APC_u13 PF16634.5 CRK39792.1 - 0.0092 15.9 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 1 Unstructured region on APC between APC_crr and SAMP Ank_2 PF12796.7 CRK39793.1 - 2.8e-16 59.8 2.8 1.5e-05 25.5 0.7 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CRK39793.1 - 5.6e-13 49.1 1.4 0.00068 20.1 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 CRK39793.1 - 1.9e-12 47.0 1.5 0.00012 22.4 0.1 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 CRK39793.1 - 7.8e-12 44.3 0.5 0.0077 16.7 0.1 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 CRK39793.1 - 2.9e-10 40.2 3.3 1.3e-05 25.3 0.2 3.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) KilA-N PF04383.13 CRK39793.1 - 7.8e-07 28.9 0.3 3.7e-06 26.8 0.3 2.0 1 1 0 1 1 1 1 KilA-N domain Aldo_ket_red PF00248.21 CRK39794.1 - 1.5e-51 175.3 0.0 1.7e-51 175.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family APC_u13 PF16634.5 CRK39794.1 - 0.0063 16.4 0.1 0.027 14.4 0.0 2.0 2 0 0 2 2 2 1 Unstructured region on APC between APC_crr and SAMP Hexapep PF00132.24 CRK39796.1 - 5.7e-10 38.5 6.5 1.2e-05 24.9 1.1 4.6 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 CRK39796.1 - 0.00062 19.5 0.3 1.8 8.4 0.1 3.2 4 0 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase G_glu_transpept PF01019.21 CRK39797.1 - 3.8e-127 425.2 0.0 1.6e-58 198.7 0.0 3.0 1 1 2 3 3 3 3 Gamma-glutamyltranspeptidase DUF4429 PF14472.6 CRK39797.1 - 0.0018 18.8 0.0 3.5 8.3 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4429) Cdc6_C PF09079.11 CRK39797.1 - 0.0048 16.8 0.0 4.4 7.4 0.0 2.4 2 0 0 2 2 2 2 CDC6, C terminal winged helix domain TUDOR_5 PF18359.1 CRK39797.1 - 0.035 13.8 0.2 15 5.4 0.0 2.7 2 0 0 2 2 2 0 Histone methyltransferase Tudor domain 1 Hema_HEFG PF02710.14 CRK39797.1 - 0.11 12.7 0.2 0.61 10.3 0.2 2.0 1 1 0 1 1 1 0 Hemagglutinin domain of haemagglutinin-esterase-fusion glycoprotein NitrOD2 PF18550.1 CRK39797.1 - 0.11 12.7 0.0 23 5.2 0.0 2.4 2 0 0 2 2 2 0 Nitrososphaera output domain 2 Hexapep PF00132.24 CRK39798.1 - 3.6e-10 39.2 6.5 8.8e-06 25.3 1.1 4.2 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 CRK39798.1 - 0.00034 20.3 0.3 1.4 8.8 0.1 3.2 4 0 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase G_glu_transpept PF01019.21 CRK39799.1 - 2.9e-88 296.9 0.0 5.5e-66 223.4 0.0 2.0 1 1 1 2 2 2 2 Gamma-glutamyltranspeptidase Glutaredoxin PF00462.24 CRK39800.1 - 6.7e-15 55.1 0.0 1.1e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Flavoprotein PF02441.19 CRK39801.1 - 2.7e-43 147.5 0.0 3.2e-43 147.2 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein Chitin_synth_1 PF01644.17 CRK39802.1 - 1.8e-73 245.9 0.1 2.7e-73 245.3 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 CRK39802.1 - 2.3e-29 101.2 0.0 4.9e-29 100.1 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 CRK39802.1 - 3.9e-21 75.3 0.8 5.3e-17 61.6 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 CRK39802.1 - 5.7e-05 23.1 11.0 5.7e-05 23.1 11.0 2.6 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Sec1 PF00995.23 CRK39803.1 - 5.9e-117 392.3 0.0 6.8e-117 392.1 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DUF3455 PF11937.8 CRK39804.1 - 5.2e-26 91.9 0.0 1.8e-25 90.2 0.0 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) DUF3886 PF13025.6 CRK39804.1 - 0.014 15.6 1.3 0.014 15.6 1.3 5.1 6 0 0 6 6 6 0 Protein of unknown function (DUF3886) Pkinase PF00069.25 CRK39805.1 - 3.9e-29 101.8 0.0 1.6e-15 57.2 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CRK39805.1 - 6.5e-07 28.9 0.2 7.1e-05 22.2 0.1 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase LMWPc PF01451.21 CRK39806.1 - 6.4e-40 136.8 0.0 7.3e-40 136.6 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase CFEM PF05730.11 CRK39807.1 - 1.8e-11 43.9 11.6 3.6e-11 43.0 11.6 1.5 1 0 0 1 1 1 1 CFEM domain Dicty_REP PF05086.12 CRK39807.1 - 0.33 8.9 0.7 0.39 8.6 0.7 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Gamma-thionin PF00304.20 CRK39807.1 - 0.99 9.7 7.4 0.35 11.1 1.2 2.4 2 1 0 2 2 2 0 Gamma-thionin family PCRF PF03462.18 CRK39808.1 - 7.9e-39 133.5 0.1 2.7e-37 128.5 0.1 2.5 1 1 0 1 1 1 1 PCRF domain RF-1 PF00472.20 CRK39808.1 - 5.4e-33 113.4 0.7 1.2e-32 112.2 0.7 1.6 1 0 0 1 1 1 1 RF-1 domain SPAM PF02090.15 CRK39808.1 - 0.012 15.5 2.1 1 9.2 0.0 2.3 2 0 0 2 2 2 0 Salmonella surface presentation of antigen gene type M protein PRELI PF04707.14 CRK39809.1 - 3.7e-18 65.8 0.1 5.5e-15 55.5 0.0 2.3 2 0 0 2 2 2 2 PRELI-like family Abhydrolase_6 PF12697.7 CRK39809.1 - 3.8e-10 40.7 5.3 9.3e-10 39.5 5.3 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CRK39809.1 - 0.00028 20.2 0.1 0.032 13.5 0.0 2.4 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CRK39809.1 - 0.00053 19.7 0.0 0.0016 18.1 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold GWT1 PF06423.12 CRK39810.1 - 0.024 14.7 0.5 0.041 14.0 0.3 1.6 1 1 0 1 1 1 0 GWT1 TRP PF06011.12 CRK39811.1 - 9.3e-134 446.3 28.4 9.3e-134 446.3 28.4 1.6 2 0 0 2 2 2 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 CRK39811.1 - 1.6e-19 70.6 0.6 7.6e-19 68.5 0.1 2.0 1 1 1 2 2 2 2 ML-like domain 4HBT_2 PF13279.6 CRK39812.1 - 4.3e-08 33.7 0.0 6.8e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily NmrA PF05368.13 CRK39813.1 - 9e-68 228.3 0.1 9.2e-36 123.5 0.0 2.2 2 0 0 2 2 2 2 NmrA-like family RPA43_OB PF17875.1 CRK39813.1 - 3.9e-35 121.2 0.1 3.9e-35 121.2 0.1 4.2 3 1 0 3 3 2 1 RPA43 OB domain in RNA Pol I NAD_binding_10 PF13460.6 CRK39813.1 - 1.5e-26 93.4 0.8 6.5e-16 58.7 0.1 2.6 2 1 0 2 2 2 2 NAD(P)H-binding Epimerase PF01370.21 CRK39813.1 - 1e-09 38.2 0.1 0.0041 16.6 0.0 3.3 3 0 0 3 3 3 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CRK39813.1 - 3.3e-08 32.9 0.1 0.0009 18.3 0.1 2.2 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 CRK39813.1 - 6.6e-06 26.6 0.2 0.00011 22.6 0.0 2.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.18 CRK39813.1 - 0.00031 21.0 0.6 0.39 11.0 0.2 2.5 2 0 0 2 2 2 2 TrkA-N domain KR PF08659.10 CRK39813.1 - 0.00037 20.5 0.4 0.0022 17.9 0.0 2.2 2 0 0 2 2 2 1 KR domain Glu_dehyd_C PF16912.5 CRK39813.1 - 0.0028 17.2 0.0 0.0059 16.1 0.0 1.5 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus Sacchrp_dh_NADP PF03435.18 CRK39813.1 - 0.011 16.0 5.0 0.055 13.7 0.1 3.4 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain DXP_reductoisom PF02670.16 CRK39813.1 - 0.012 16.4 0.3 10 6.8 0.0 2.8 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase SHS2_Rpb7-N PF03876.17 CRK39813.1 - 0.021 15.2 0.0 0.06 13.7 0.0 1.8 1 0 0 1 1 1 0 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Polysacc_synt_2 PF02719.15 CRK39813.1 - 0.043 13.0 0.2 0.11 11.5 0.1 1.8 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 CRK39813.1 - 0.058 12.6 0.1 2 7.5 0.0 2.4 2 0 0 2 2 2 0 Male sterility protein adh_short PF00106.25 CRK39813.1 - 0.088 12.3 0.3 0.32 10.4 0.1 2.1 2 0 0 2 2 2 0 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 CRK39813.1 - 0.16 11.4 1.6 0.7 9.2 0.0 2.6 3 0 0 3 3 3 0 GDP-mannose 4,6 dehydratase SOBP PF15279.6 CRK39813.1 - 8.8 6.8 16.2 18 5.9 16.2 1.5 1 0 0 1 1 1 0 Sine oculis-binding protein Actin PF00022.19 CRK39814.1 - 7.1e-109 364.1 0.0 2.3e-108 362.4 0.0 1.7 1 1 0 1 1 1 1 Actin Sugar_tr PF00083.24 CRK39814.1 - 3.9e-88 296.3 7.0 5.9e-88 295.7 7.0 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter Pkinase PF00069.25 CRK39814.1 - 2.1e-63 214.1 0.0 3.9e-63 213.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK39814.1 - 6.8e-30 104.2 0.0 1.1e-29 103.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase MFS_1 PF07690.16 CRK39814.1 - 1e-25 90.5 50.6 7e-23 81.1 29.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Asp_Glu_race PF01177.22 CRK39815.1 - 0.0039 17.1 0.0 0.12 12.2 0.0 2.1 2 0 0 2 2 2 1 Asp/Glu/Hydantoin racemase YopE PF03545.13 CRK39815.1 - 0.087 13.0 0.1 0.19 11.9 0.1 1.6 1 0 0 1 1 1 0 Yersinia virulence determinant (YopE) Ribosomal_S24e PF01282.19 CRK39816.1 - 2.8e-35 120.1 0.0 5.3e-35 119.2 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein S24e Methyltransf_16 PF10294.9 CRK39817.1 - 1e-17 64.5 0.0 1.6e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 CRK39817.1 - 0.00031 20.6 0.0 0.00045 20.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK39817.1 - 0.0014 19.3 0.0 0.0033 18.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.12 CRK39817.1 - 0.0064 16.3 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_12 PF08242.12 CRK39817.1 - 0.01 16.6 0.0 0.023 15.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 CRK39817.1 - 0.011 15.5 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 CRK39817.1 - 0.014 15.0 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.6 CRK39817.1 - 0.027 14.3 0.1 0.053 13.3 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.16 CRK39817.1 - 0.09 12.5 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein LRRCT PF01463.24 CRK39817.1 - 0.14 12.7 0.1 0.59 10.8 0.0 2.1 2 0 0 2 2 2 0 Leucine rich repeat C-terminal domain PrmA PF06325.13 CRK39817.1 - 0.19 11.1 0.0 0.32 10.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Pheromone PF08015.11 CRK39819.1 - 2.8 9.1 8.7 56 4.9 8.7 2.3 1 1 0 1 1 1 0 Fungal mating-type pheromone Pro_isomerase PF00160.21 CRK39820.1 - 3.1e-34 118.5 0.0 4.8e-34 117.9 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 CRK39820.1 - 8.6e-14 51.1 0.0 1.5e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PMI_typeI PF01238.21 CRK39822.1 - 5.8e-141 470.0 0.0 6.7e-141 469.8 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I DUF1325 PF07039.11 CRK39823.1 - 2.1e-29 102.2 0.0 3.5e-29 101.6 0.0 1.3 1 0 0 1 1 1 1 SGF29 tudor-like domain CNTF PF01110.17 CRK39823.1 - 0.12 11.8 0.1 0.17 11.2 0.1 1.2 1 0 0 1 1 1 0 Ciliary neurotrophic factor PAD_N PF08526.10 CRK39823.1 - 0.17 12.3 0.0 0.3 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) N-terminal domain DUF3138 PF11336.8 CRK39823.1 - 0.18 10.4 4.7 0.29 9.7 4.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Arf PF00025.21 CRK39825.1 - 8.8e-75 250.0 0.2 1e-74 249.8 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CRK39825.1 - 5.4e-14 52.4 0.0 7.7e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CRK39825.1 - 7.1e-13 48.5 0.0 8e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 CRK39825.1 - 3.9e-12 46.0 2.4 2.2e-08 33.6 0.3 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 CRK39825.1 - 7.8e-12 45.0 0.0 9.9e-12 44.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CRK39825.1 - 3.8e-11 42.8 0.0 4.8e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CRK39825.1 - 0.00054 20.0 0.0 0.00074 19.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SpoOE-like PF09388.10 CRK39825.1 - 0.035 14.0 0.8 0.062 13.2 0.8 1.4 1 0 0 1 1 1 0 Spo0E like sporulation regulatory protein 6PF2K PF01591.18 CRK39825.1 - 0.047 13.0 0.3 0.089 12.1 0.1 1.5 2 0 0 2 2 2 0 6-phosphofructo-2-kinase Methyltrn_RNA_3 PF02598.17 CRK39825.1 - 0.051 13.1 0.0 0.061 12.8 0.0 1.1 1 0 0 1 1 1 0 Putative RNA methyltransferase GTP_cyclohydro2 PF00925.20 CRK39827.1 - 1.4e-59 200.3 0.0 3e-59 199.3 0.0 1.5 1 0 0 1 1 1 1 GTP cyclohydrolase II FHA PF00498.26 CRK39829.1 - 1.5e-08 34.9 0.1 2.6e-08 34.1 0.1 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CRK39829.1 - 8.7e-05 22.8 0.1 0.00022 21.5 0.0 1.6 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain NDUF_B7 PF05676.13 CRK39831.1 - 2.1e-30 104.3 3.9 2.4e-30 104.0 3.9 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 CRK39831.1 - 0.0024 17.8 1.2 0.0031 17.5 1.2 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like DUF1325 PF07039.11 CRK39833.1 - 8.5e-33 113.2 0.0 1.3e-32 112.6 0.0 1.3 1 0 0 1 1 1 1 SGF29 tudor-like domain TetR_C_14 PF17754.1 CRK39833.1 - 0.075 13.0 1.5 0.15 12.0 1.5 1.4 1 0 0 1 1 1 0 MftR C-terminal domain DUF3138 PF11336.8 CRK39833.1 - 0.23 10.1 5.3 0.36 9.4 5.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Arf PF00025.21 CRK39835.1 - 5.6e-74 247.3 0.2 7.2e-74 247.0 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CRK39835.1 - 2.3e-13 50.4 0.0 3.4e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CRK39835.1 - 3.7e-12 46.1 0.0 4.6e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 CRK39835.1 - 2.4e-11 43.4 1.8 9e-08 31.7 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 CRK39835.1 - 3.8e-11 42.7 0.0 5.1e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CRK39835.1 - 1.8e-10 40.6 0.0 2.4e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CRK39835.1 - 0.0024 17.9 0.0 0.0037 17.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SpoOE-like PF09388.10 CRK39835.1 - 0.085 12.8 0.8 0.14 12.1 0.8 1.3 1 0 0 1 1 1 0 Spo0E like sporulation regulatory protein 6PF2K PF01591.18 CRK39835.1 - 0.15 11.4 0.1 0.27 10.5 0.1 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Methyltrn_RNA_3 PF02598.17 CRK39835.1 - 0.17 11.4 0.0 0.24 10.8 0.0 1.1 1 0 0 1 1 1 0 Putative RNA methyltransferase FHA PF00498.26 CRK39838.1 - 1.7e-07 31.4 0.1 3.1e-07 30.6 0.1 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CRK39838.1 - 8.1e-05 22.9 0.1 0.00026 21.2 0.0 1.8 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain NDUF_B7 PF05676.13 CRK39840.1 - 2e-30 104.3 3.9 2.4e-30 104.0 3.9 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 CRK39840.1 - 0.0019 18.2 1.2 0.0024 17.8 1.2 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Aa_trans PF01490.18 CRK39841.1 - 4.8e-28 98.0 32.9 3e-27 95.4 14.6 2.0 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CRK39841.1 - 0.00023 20.4 14.8 0.00023 20.4 14.8 1.7 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family DUF2207 PF09972.9 CRK39841.1 - 3.9 6.1 0.0 3.9 6.1 0.0 3.2 3 1 0 3 3 3 0 Predicted membrane protein (DUF2207) PilN PF05137.13 CRK39842.1 - 0.15 12.3 0.7 3.4 7.9 0.1 2.7 2 0 0 2 2 2 0 Fimbrial assembly protein (PilN) OFCC1 PF15680.5 CRK39843.1 - 0.041 14.5 0.1 11 6.6 0.0 2.1 1 1 1 2 2 2 0 Orofacial cleft 1 candidate gene 1 protein MFS_1 PF07690.16 CRK39844.1 - 2.5e-32 112.2 31.3 3.5e-32 111.7 31.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily zf-RING_2 PF13639.6 CRK39845.1 - 9.6e-09 35.4 5.8 9.6e-09 35.4 5.8 2.2 2 0 0 2 2 2 1 Ring finger domain zf-ANAPC11 PF12861.7 CRK39845.1 - 0.00029 20.8 1.5 0.00029 20.8 1.5 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 CRK39845.1 - 0.00085 19.6 4.7 0.00085 19.6 4.7 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_4 PF14570.6 CRK39845.1 - 0.00088 19.0 5.5 0.00088 19.0 5.5 2.0 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 CRK39845.1 - 0.002 18.1 2.9 0.0065 16.5 2.9 2.0 1 0 0 1 1 1 1 RING-type zinc-finger FANCL_C PF11793.8 CRK39845.1 - 0.0021 18.2 7.9 0.0065 16.6 5.1 2.5 2 0 0 2 2 2 1 FANCL C-terminal domain PHD PF00628.29 CRK39845.1 - 0.0058 16.5 6.5 0.013 15.4 6.5 1.6 1 0 0 1 1 1 1 PHD-finger zf-RING_5 PF14634.6 CRK39845.1 - 0.021 14.8 4.9 0.021 14.8 4.9 2.1 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING-like PF08746.11 CRK39845.1 - 0.022 15.1 4.3 0.022 15.1 4.3 2.2 3 0 0 3 3 1 0 RING-like domain Prok-RING_1 PF14446.6 CRK39845.1 - 0.025 14.5 2.5 0.025 14.5 2.5 2.7 2 1 1 3 3 2 0 Prokaryotic RING finger family 1 SWIM PF04434.17 CRK39845.1 - 0.05 13.3 0.2 0.12 12.1 0.2 1.5 1 0 0 1 1 1 0 SWIM zinc finger NOA36 PF06524.12 CRK39845.1 - 0.058 12.7 7.4 0.1 11.9 7.4 1.3 1 0 0 1 1 1 0 NOA36 protein zf-C3HC4_3 PF13920.6 CRK39845.1 - 0.061 13.2 3.0 0.17 11.8 3.0 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 CRK39845.1 - 0.072 13.2 1.8 0.29 11.3 1.8 2.1 1 0 0 1 1 1 0 Zinc-binding RING-finger RINGv PF12906.7 CRK39845.1 - 0.11 12.6 7.8 0.25 11.5 7.8 1.6 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.6 CRK39845.1 - 0.15 12.3 4.3 1.6 9.0 4.3 2.4 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING ORC6 PF05460.13 CRK39845.1 - 0.32 10.2 5.1 0.51 9.6 5.1 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) zf-C3HC4_2 PF13923.6 CRK39845.1 - 2.4 8.1 13.6 0.035 14.0 5.5 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CRK39845.1 - 9.2 6.2 13.1 0.13 12.2 5.1 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) SnoaL_2 PF12680.7 CRK39847.1 - 0.0045 17.6 0.0 0.007 17.0 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain DUF2358 PF10184.9 CRK39847.1 - 0.083 13.2 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2358) Oxysterol_BP PF01237.18 CRK39848.1 - 9.7e-30 103.6 0.7 5.2e-23 81.5 0.1 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein GTP_EFTU PF00009.27 CRK39857.1 - 1.1e-39 136.0 0.0 1.8e-39 135.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 CRK39857.1 - 8e-31 106.3 0.0 2.2e-30 104.9 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 CRK39857.1 - 1.4e-22 79.5 0.0 4e-22 78.1 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 CRK39857.1 - 7.3e-13 48.7 0.1 2.9e-12 46.8 0.1 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 CRK39857.1 - 4e-12 46.1 0.0 1.2e-11 44.5 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II PduV-EutP PF10662.9 CRK39857.1 - 0.1 12.4 0.1 0.17 11.6 0.1 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Sod_Cu PF00080.20 CRK39860.1 - 1.7e-08 34.7 0.0 1.8e-08 34.6 0.0 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) polyprenyl_synt PF00348.17 CRK39873.1 - 9.6e-05 21.6 0.0 0.00012 21.3 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Fungal_trans PF04082.18 CRK39877.1 - 1.9e-14 53.3 0.0 1.1e-13 50.8 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Flavi_NS4A PF01350.17 CRK39877.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Flavivirus non-structural protein NS4A TFIIA PF03153.13 CRK39877.1 - 1.2 9.1 5.9 1.6 8.6 5.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AA_permease PF00324.21 CRK39878.1 - 7.8e-17 61.0 4.9 7.8e-17 61.0 4.9 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease_2 PF13520.6 CRK39878.1 - 4.6e-05 22.4 7.7 6.6e-05 21.9 7.6 1.3 1 1 0 1 1 1 1 Amino acid permease TMEM220 PF15071.6 CRK39878.1 - 0.016 16.0 2.1 0.043 14.6 1.4 2.0 2 0 0 2 2 2 0 Transmembrane family 220, helix 7TM_GPCR_Sra PF02117.16 CRK39878.1 - 0.019 13.8 0.6 0.028 13.2 0.6 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sra Polysacc_synt_C PF14667.6 CRK39878.1 - 1.2 9.2 10.6 0.11 12.6 3.3 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain Zn_clus PF00172.18 CRK39882.1 - 6.2e-08 32.6 8.4 1.1e-07 31.9 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fn3-like PF14310.6 CRK39883.1 - 2.8e-15 56.2 0.1 4.5e-15 55.5 0.1 1.3 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF4232 PF14016.6 CRK39883.1 - 0.0052 16.9 0.6 0.0077 16.4 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4232) fn3_5 PF06280.12 CRK39883.1 - 0.013 16.2 0.2 0.065 13.9 0.2 1.8 1 1 0 1 1 1 0 Fn3-like domain CARDB PF07705.11 CRK39883.1 - 0.02 15.2 0.1 0.025 14.8 0.1 1.2 1 0 0 1 1 1 0 CARDB Ig_GlcNase PF18368.1 CRK39883.1 - 0.039 14.1 0.1 0.05 13.8 0.1 1.1 1 0 0 1 1 1 0 Exo-beta-D-glucosaminidase Ig-fold domain ZirS_C PF16583.5 CRK39883.1 - 0.042 13.4 0.2 0.052 13.1 0.2 1.1 1 0 0 1 1 1 0 Zinc-regulated secreted antivirulence protein C-terminal domain DUF916 PF06030.12 CRK39883.1 - 0.1 12.6 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF916) RPOL_N PF14700.6 CRK39890.1 - 2.5e-28 99.5 0.0 3.4e-28 99.0 0.0 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal DUF3675 PF12428.8 CRK39890.1 - 0.085 13.4 0.2 2.3 8.8 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3675) Glyco_hydro_18 PF00704.28 CRK39895.1 - 7.4e-10 39.0 0.1 7.7e-10 39.0 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Cu_amine_oxid PF01179.20 CRK39897.1 - 3.5e-11 42.7 0.0 3.6e-11 42.6 0.0 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1729 PF08354.10 CRK39898.1 - 5.4e-155 515.6 0.0 8.3e-155 515.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) FAS_meander PF17951.1 CRK39898.1 - 5.5e-53 178.7 0.0 1.3e-52 177.5 0.0 1.7 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain SAT PF16073.5 CRK39898.1 - 1.3e-22 80.8 0.1 2.1e-22 80.0 0.1 1.3 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydrat_N PF13452.6 CRK39898.1 - 1.1e-15 57.9 0.0 3.8e-15 56.2 0.0 2.0 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase Amidohydro_1 PF01979.20 CRK39898.1 - 6.2e-12 45.5 0.0 1.2e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase family Acyl_transf_1 PF00698.21 CRK39898.1 - 9.7e-08 31.9 0.2 6.1e-07 29.2 0.0 2.2 3 0 0 3 3 3 1 Acyl transferase domain NMO PF03060.15 CRK39898.1 - 0.098 12.0 0.7 0.62 9.4 0.7 2.1 1 1 0 1 1 1 0 Nitronate monooxygenase Fas_alpha_ACP PF18325.1 CRK39900.1 - 5e-77 257.8 0.0 6.9e-77 257.3 0.0 1.2 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain PP-binding PF00550.25 CRK39900.1 - 0.17 12.3 0.0 0.58 10.6 0.0 1.8 1 1 1 2 2 2 0 Phosphopantetheine attachment site UCR_14kD PF02271.16 CRK39906.1 - 6.4e-23 80.6 0.2 6.9e-23 80.5 0.2 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit adh_short_C2 PF13561.6 CRK39907.1 - 8e-05 22.3 0.1 9.5e-05 22.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRK39907.1 - 0.00013 21.5 0.1 0.00014 21.4 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase PA PF02225.22 CRK39907.1 - 0.0019 18.2 0.0 0.002 18.1 0.0 1.1 1 0 0 1 1 1 1 PA domain KR PF08659.10 CRK39907.1 - 0.04 13.8 0.0 0.045 13.7 0.0 1.1 1 0 0 1 1 1 0 KR domain ThiF PF00899.21 CRK39907.1 - 0.058 12.7 0.0 0.076 12.4 0.0 1.1 1 0 0 1 1 1 0 ThiF family URO-D PF01208.17 CRK39907.1 - 0.13 11.3 0.0 0.14 11.3 0.0 1.0 1 0 0 1 1 1 0 Uroporphyrinogen decarboxylase (URO-D) G-patch PF01585.23 CRK39908.1 - 7.3e-11 41.8 1.9 1e-10 41.3 1.9 1.3 1 0 0 1 1 1 1 G-patch domain PQ-loop PF04193.14 CRK39911.1 - 1.7e-37 127.0 14.4 3e-19 68.5 2.0 3.1 3 0 0 3 3 3 2 PQ loop repeat MFS_1 PF07690.16 CRK39911.1 - 2.3e-09 36.7 18.8 2.4e-07 30.0 14.2 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily NUDIX PF00293.28 CRK39912.1 - 2.8e-16 59.7 0.0 5.1e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.11 CRK39912.1 - 4.7e-13 49.7 0.0 1.4e-12 48.1 0.0 1.8 3 0 0 3 3 3 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 CRK39912.1 - 4.4e-07 29.4 3.6 7e-07 28.8 3.6 1.3 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Reticulon PF02453.17 CRK39913.1 - 6e-15 55.5 0.3 9.3e-15 54.9 0.3 1.2 1 0 0 1 1 1 1 Reticulon Pex24p PF06398.11 CRK39913.1 - 0.031 13.3 0.7 0.048 12.6 0.7 1.3 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin G0-G1_switch_2 PF15103.6 CRK39913.1 - 0.054 13.9 0.9 0.14 12.6 0.0 2.2 3 1 0 3 3 3 0 G0/G1 switch protein 2 YtxH PF12732.7 CRK39913.1 - 1.2 9.8 7.6 95 3.6 7.6 2.5 1 1 0 1 1 1 0 YtxH-like protein COX16 PF14138.6 CRK39915.1 - 2.6e-17 63.1 0.2 2.8e-17 63.0 0.2 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 Ribosomal_L34e PF01199.18 CRK39918.1 - 6.2e-17 61.7 0.1 1e-16 61.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L34e OPT PF03169.15 CRK39933.1 - 1.8e-118 396.8 47.5 2.2e-118 396.6 47.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein CopD PF05425.13 CRK39934.1 - 0.075 13.4 8.0 0.14 12.6 2.3 2.3 2 0 0 2 2 2 0 Copper resistance protein D AA_permease PF00324.21 CRK39935.1 - 2.7e-108 362.6 37.2 3.3e-108 362.3 37.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CRK39935.1 - 3.4e-28 98.6 40.7 4.1e-28 98.4 40.7 1.0 1 0 0 1 1 1 1 Amino acid permease Septin PF00735.18 CRK39943.1 - 1.3e-32 113.2 0.0 3.7e-12 46.1 0.0 3.1 3 0 0 3 3 3 3 Septin AAA_23 PF13476.6 CRK39943.1 - 0.0032 18.0 0.0 0.01 16.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 CRK39943.1 - 0.013 14.9 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_16 PF13191.6 CRK39943.1 - 0.018 15.4 0.1 0.069 13.5 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain DUF3313 PF11769.8 CRK39943.1 - 0.032 14.1 0.1 0.12 12.1 0.0 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF3313) AAA_18 PF13238.6 CRK39943.1 - 0.037 14.6 0.1 0.51 10.9 0.0 2.6 2 1 0 2 2 2 0 AAA domain Pox_A32 PF04665.12 CRK39943.1 - 0.2 11.1 0.0 0.31 10.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein ABC1 PF03109.16 CRK39944.1 - 1.5e-20 73.6 0.0 3e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 CRK39944.1 - 0.0008 19.4 0.0 0.0058 16.6 0.0 2.3 2 1 0 2 2 2 1 Phosphotransferase enzyme family IF3_C PF00707.22 CRK39944.1 - 0.18 11.8 0.7 1.3 9.0 0.1 2.5 3 0 0 3 3 3 0 Translation initiation factor IF-3, C-terminal domain ABC_membrane PF00664.23 CRK39959.1 - 7.9e-05 22.4 0.2 8.6e-05 22.3 0.2 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region DUF3671 PF12420.8 CRK39959.1 - 0.057 13.5 0.3 0.061 13.4 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function Fungal_trans PF04082.18 CRK39960.1 - 2.9e-06 26.5 0.7 3e-06 26.5 0.7 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sec34 PF04136.15 CRK39963.1 - 0.046 13.6 0.2 0.064 13.1 0.2 1.1 1 0 0 1 1 1 0 Sec34-like family Zn_clus PF00172.18 CRK39963.1 - 0.26 11.4 10.0 0.71 10.0 10.0 1.7 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Atg14 PF10186.9 CRK39963.1 - 0.26 10.3 3.6 0.32 10.0 3.6 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 RTA1 PF04479.13 CRK39964.1 - 7.2e-43 146.6 8.4 2.5e-42 144.8 8.4 1.7 1 1 0 1 1 1 1 RTA1 like protein CFEM PF05730.11 CRK39967.1 - 1.8e-12 47.2 6.8 2.8e-12 46.6 6.8 1.3 1 0 0 1 1 1 1 CFEM domain Dicistro_VP4 PF11492.8 CRK39967.1 - 0.033 14.1 2.0 0.35 10.9 1.0 2.4 2 0 0 2 2 2 0 Cricket paralysis virus, VP4 DUF3446 PF11928.8 CRK39967.1 - 3.7 7.9 12.1 0.43 10.9 3.3 2.3 2 0 0 2 2 2 0 Early growth response N-terminal domain cobW PF02492.19 CRK39968.1 - 1.4e-48 164.8 8.0 5.8e-37 127.0 0.8 2.2 1 1 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 CRK39968.1 - 2.7e-17 62.5 0.2 5.6e-13 48.6 0.0 2.5 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain MeaB PF03308.16 CRK39968.1 - 2.3e-05 23.5 0.2 0.0049 15.9 0.0 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB Viral_helicase1 PF01443.18 CRK39968.1 - 0.0078 16.0 0.1 0.015 15.0 0.1 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase TsaE PF02367.17 CRK39968.1 - 0.0089 16.0 0.1 0.024 14.6 0.1 1.7 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE MobB PF03205.14 CRK39968.1 - 0.0096 15.8 0.1 0.024 14.6 0.1 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.6 CRK39968.1 - 0.015 15.7 0.4 0.063 13.7 0.4 2.1 1 1 0 1 1 1 0 AAA ATPase domain GTP_EFTU PF00009.27 CRK39968.1 - 0.026 14.1 1.9 0.72 9.4 0.1 2.5 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 CRK39968.1 - 0.068 12.9 0.1 0.17 11.6 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 CRK39968.1 - 0.087 13.0 0.9 0.26 11.5 0.1 2.3 3 1 0 3 3 3 0 AAA domain AAA_18 PF13238.6 CRK39968.1 - 0.092 13.3 0.4 1.4 9.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 CRK39968.1 - 0.44 11.0 2.0 0.84 10.1 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_11 PF13086.6 CRK39968.1 - 0.92 9.2 3.0 4.4 7.0 0.1 2.5 2 1 0 3 3 3 0 AAA domain COesterase PF00135.28 CRK39970.1 - 4.1e-122 408.7 0.0 2e-62 211.7 0.0 4.1 2 2 2 4 4 4 4 Carboxylesterase family Endopep_inhib PF16800.5 CRK39970.1 - 2.8e-05 24.1 0.0 4.5 7.2 0.0 3.3 3 0 0 3 3 3 3 IseA DL-endopeptidase inhibitor Abhydrolase_3 PF07859.13 CRK39970.1 - 0.027 14.3 1.6 0.069 13.0 0.2 2.3 2 1 0 2 2 2 0 alpha/beta hydrolase fold DotD PF16816.5 CRK39970.1 - 0.082 12.9 0.0 27 4.8 0.0 2.8 2 0 0 2 2 2 0 DotD protein RNA_pol_Rpb1_3 PF04983.18 CRK39970.1 - 0.11 12.4 1.4 41 4.1 0.0 3.3 3 0 0 3 3 3 0 RNA polymerase Rpb1, domain 3 Astro_capsid_N PF03115.14 CRK39970.1 - 0.17 10.5 1.0 41 2.7 0.0 3.0 3 0 0 3 3 3 0 Astrovirus capsid protein precursor CT_C_D PF02682.16 CRK39970.1 - 0.18 11.5 0.2 17 5.0 0.0 2.3 2 0 0 2 2 2 0 Carboxyltransferase domain, subdomain C and D Mannosyl_trans2 PF04188.13 CRK39976.1 - 1.7e-51 176.0 6.2 1.1e-50 173.2 6.2 1.9 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V) DUF1996 PF09362.10 CRK39978.1 - 1.1e-34 120.5 0.0 1.7e-34 119.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Chitin_synth_2 PF03142.15 CRK39980.1 - 3e-42 144.9 0.2 2.9e-33 115.3 0.1 2.1 1 1 0 2 2 2 2 Chitin synthase Glycos_transf_2 PF00535.26 CRK39980.1 - 3.7e-11 43.1 0.1 1.3e-05 25.1 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 CRK39980.1 - 2.4e-08 34.1 3.6 2.4e-08 34.1 3.6 2.5 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 CRK39980.1 - 4e-07 30.2 0.4 0.00083 19.3 0.1 2.7 2 1 0 2 2 2 2 Glycosyltransferase like family 2 UDPG_MGDP_dh PF00984.19 CRK39982.1 - 3.5e-20 72.0 0.0 8.5e-20 70.8 0.0 1.7 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_N PF03721.14 CRK39982.1 - 1.5e-15 57.2 0.0 5.1e-14 52.3 0.0 2.3 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.15 CRK39982.1 - 1.6e-06 28.3 0.0 2.5e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.18 CRK39982.1 - 0.00065 19.9 0.0 0.0033 17.7 0.0 2.1 2 0 0 2 2 2 1 TrkA-N domain UDPG_MGDP_dh_C PF03720.15 CRK39982.1 - 0.033 14.6 0.0 0.067 13.6 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Methyltransf_12 PF08242.12 CRK39982.1 - 0.11 13.3 0.1 0.63 10.8 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Pec_lyase_C PF00544.19 CRK39985.1 - 8.8e-43 146.3 1.8 1.3e-42 145.8 1.8 1.3 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 CRK39985.1 - 0.00035 20.5 15.8 0.0037 17.1 6.9 2.0 1 1 1 2 2 2 2 Right handed beta helix region SKG6 PF08693.10 CRK39986.1 - 9.5e-05 21.7 2.0 0.00015 21.1 2.0 1.2 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Shisa PF13908.6 CRK39986.1 - 0.018 15.3 0.0 0.021 15.1 0.0 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator TMIE PF16038.5 CRK39986.1 - 0.17 11.7 1.9 0.27 11.1 1.9 1.2 1 0 0 1 1 1 0 TMIE protein CorA PF01544.18 CRK39987.1 - 7.8e-38 130.4 0.2 1.1e-37 130.0 0.2 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein CHASE9 PF17153.4 CRK39987.1 - 0.19 11.9 0.0 0.34 11.1 0.0 1.4 1 0 0 1 1 1 0 Periplasmic sensor domain, extracellular NAM-associated PF14303.6 CRK39989.1 - 3.1 8.5 10.8 4 8.1 10.8 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain CDH-cyt PF16010.5 CRK39990.1 - 1.8e-48 164.6 2.9 3.4e-48 163.7 2.9 1.5 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase GMC_oxred_N PF00732.19 CRK39990.1 - 9.6e-25 87.6 0.0 1.8e-24 86.7 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CRK39990.1 - 1.7e-23 83.8 0.2 3.1e-23 82.9 0.2 1.5 1 0 0 1 1 1 1 GMC oxidoreductase CBM_1 PF00734.18 CRK39990.1 - 9.1e-11 41.5 1.5 3.8e-10 39.5 1.5 2.2 1 0 0 1 1 1 1 Fungal cellulose binding domain FAD_binding_2 PF00890.24 CRK39990.1 - 3.6e-08 32.9 0.5 2.2e-07 30.4 0.5 1.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 CRK39990.1 - 2e-05 24.7 0.0 8.6e-05 22.7 0.0 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CRK39990.1 - 0.00043 19.6 0.0 0.00086 18.6 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CRK39990.1 - 0.0058 17.2 0.0 1 9.9 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CRK39990.1 - 0.0091 15.1 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 CRK39990.1 - 0.014 14.2 0.0 0.023 13.4 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 CRK39990.1 - 0.032 13.5 0.1 0.054 12.7 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 CRK39990.1 - 0.054 12.7 0.1 0.26 10.5 0.1 1.9 2 0 0 2 2 2 0 Thi4 family FAD_oxidored PF12831.7 CRK39990.1 - 0.061 12.7 0.0 1.2 8.4 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 CRK39990.1 - 0.096 11.9 1.7 0.16 11.2 0.5 1.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Lactamase_B_2 PF12706.7 CRK39991.1 - 1.7e-09 37.5 0.0 3.3e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DRMBL PF07522.14 CRK39991.1 - 0.00019 21.6 0.0 0.0005 20.2 0.0 1.7 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B PF00753.27 CRK39991.1 - 0.00019 21.5 0.0 0.00048 20.2 0.0 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Ustilago_mating PF05722.12 CRK39992.1 - 0.083 12.4 12.9 0.11 12.0 12.9 1.1 1 0 0 1 1 1 0 Ustilago B locus mating-type protein Gly-zipper_OmpA PF13436.6 CRK39992.1 - 4.8 7.0 17.0 0.13 12.1 10.4 1.8 2 0 0 2 2 2 0 Glycine-zipper domain DUF1479 PF07350.12 CRK39994.1 - 1.1e-146 488.9 0.0 1.4e-146 488.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) Ank_2 PF12796.7 CRK39995.1 - 5.8e-51 171.0 7.2 2.7e-12 47.1 0.6 5.9 2 2 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CRK39995.1 - 8.1e-33 112.4 6.2 1.9e-07 31.5 0.0 8.4 3 2 5 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 CRK39995.1 - 1.7e-28 95.5 8.6 5.3e-05 23.3 0.0 11.1 11 0 0 11 11 11 5 Ankyrin repeat Ank PF00023.30 CRK39995.1 - 1.9e-20 72.4 20.9 2.6e-05 24.4 0.0 9.4 10 0 0 10 10 10 5 Ankyrin repeat Ank_5 PF13857.6 CRK39995.1 - 8.1e-20 70.6 15.7 0.00017 21.8 0.2 9.0 4 4 6 10 10 10 6 Ankyrin repeats (many copies) ANAPC5 PF12862.7 CRK39995.1 - 0.18 11.9 0.8 2.3 8.3 0.2 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 Ank_2 PF12796.7 CRK39996.1 - 2.8e-61 204.1 0.2 1e-11 45.3 0.0 7.0 4 2 5 9 9 9 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CRK39996.1 - 3.8e-45 151.7 4.6 7.1e-06 26.5 0.0 12.2 5 5 8 14 14 14 11 Ankyrin repeats (many copies) Ank_3 PF13606.6 CRK39996.1 - 2.3e-43 141.2 8.8 0.015 15.8 0.0 15.2 16 0 0 16 16 16 11 Ankyrin repeat Ank PF00023.30 CRK39996.1 - 8.1e-37 124.1 13.6 0.01 16.2 0.0 14.7 14 1 0 14 14 14 12 Ankyrin repeat Ank_5 PF13857.6 CRK39996.1 - 4.2e-36 122.5 13.0 0.00012 22.3 0.0 10.5 7 3 4 11 11 11 9 Ankyrin repeats (many copies) Clathrin PF00637.20 CRK39996.1 - 0.21 11.5 0.0 10 6.0 0.0 3.1 3 0 0 3 3 3 0 Region in Clathrin and VPS Ldh_2 PF02615.14 CRK39997.1 - 3e-124 414.5 2.3 3.4e-124 414.3 2.3 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Fungal_trans PF04082.18 CRK39999.1 - 3e-27 95.3 0.7 5.7e-27 94.4 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK39999.1 - 2.4e-07 30.8 11.1 4.2e-07 30.0 11.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain OFeT_1 PF16955.5 CRK39999.1 - 0.17 11.6 0.1 0.28 10.9 0.1 1.3 1 0 0 1 1 1 0 Ferrous iron uptake permease, iron-lead transporter PT PF04886.12 CRK39999.1 - 2 8.1 11.5 0.084 12.4 4.9 2.0 2 0 0 2 2 2 0 PT repeat Dabb PF07876.12 CRK40000.1 - 6.7e-09 36.3 0.4 1.8e-08 34.9 0.4 1.8 1 1 0 1 1 1 1 Stress responsive A/B Barrel Domain adh_short_C2 PF13561.6 CRK40001.1 - 1e-54 185.6 1.4 2e-52 178.1 1.4 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRK40001.1 - 3.2e-41 140.9 0.8 4.1e-41 140.6 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CRK40001.1 - 0.0017 18.3 0.1 0.0026 17.7 0.1 1.2 1 0 0 1 1 1 1 KR domain SLAC1 PF03595.17 CRK40002.1 - 2.4e-66 224.2 44.2 2.8e-66 224.0 44.2 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Aa_trans PF01490.18 CRK40003.1 - 3.9e-31 108.2 31.5 4.4e-31 108.0 31.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2007 PF09413.10 CRK40005.1 - 0.00067 19.8 0.0 0.0017 18.5 0.0 1.6 2 0 0 2 2 2 1 Putative prokaryotic signal transducing protein CTP_transf_like PF01467.26 CRK40007.1 - 5e-25 88.4 0.0 7.5e-22 78.1 0.0 3.2 2 1 0 3 3 3 3 Cytidylyltransferase-like HEAT PF02985.22 CRK40009.1 - 2.1e-15 55.5 1.7 0.00015 21.7 0.0 5.7 6 0 0 6 6 5 3 HEAT repeat HEAT_2 PF13646.6 CRK40009.1 - 5.2e-12 46.0 0.4 0.042 14.2 0.2 4.9 4 0 0 4 4 4 3 HEAT repeats HEAT_EZ PF13513.6 CRK40009.1 - 3.8e-10 40.0 8.9 0.041 14.4 0.0 7.5 9 1 1 10 10 10 3 HEAT-like repeat Cnd1 PF12717.7 CRK40009.1 - 8.2e-10 39.0 0.0 8.7e-05 22.6 0.0 3.3 2 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 CRK40009.1 - 3.9e-05 23.3 0.0 0.0065 16.1 0.0 3.4 4 0 0 4 4 4 1 CLASP N terminal Adaptin_N PF01602.20 CRK40009.1 - 5e-05 22.1 0.3 0.51 8.8 0.1 3.2 2 1 0 3 3 3 3 Adaptin N terminal region Arm PF00514.23 CRK40009.1 - 0.00016 21.6 0.3 2 8.6 0.0 5.2 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.7 CRK40009.1 - 0.00017 22.1 0.0 0.2 12.3 0.0 4.0 2 1 2 4 4 4 1 Vacuolar 14 Fab1-binding region RIX1 PF08167.12 CRK40009.1 - 0.00037 20.3 0.9 0.09 12.5 0.0 3.4 3 0 0 3 3 3 1 rRNA processing/ribosome biogenesis ParcG PF10274.9 CRK40009.1 - 0.0012 18.9 0.1 0.54 10.4 0.0 4.0 3 2 2 5 5 5 1 Parkin co-regulated protein MMS19_C PF12460.8 CRK40009.1 - 0.14 11.2 2.9 0.31 10.1 0.2 2.6 2 1 0 2 2 2 0 RNAPII transcription regulator C-terminal IFRD PF05004.13 CRK40009.1 - 0.24 10.4 1.0 6.9 5.7 0.7 2.8 2 1 2 4 4 4 0 Interferon-related developmental regulator (IFRD) Sugar_tr PF00083.24 CRK40011.1 - 8.1e-71 239.2 18.1 2.1e-68 231.2 18.1 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK40011.1 - 1.1e-16 60.8 18.6 4.1e-14 52.3 12.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Alpha-amylase PF00128.24 CRK40012.1 - 5.2e-110 368.1 0.0 9.8e-110 367.3 0.0 1.4 2 0 0 2 2 2 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 CRK40012.1 - 0.0017 17.5 0.0 0.0035 16.5 0.0 1.4 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain Malt_amylase_C PF16657.5 CRK40012.1 - 0.021 14.9 0.0 0.049 13.8 0.0 1.6 1 0 0 1 1 1 0 Maltogenic Amylase, C-terminal domain Aminotran_5 PF00266.19 CRK40012.1 - 0.17 10.8 0.0 2 7.3 0.0 2.0 2 0 0 2 2 2 0 Aminotransferase class-V zf-U1 PF06220.12 CRK40015.1 - 7.2e-06 25.7 0.2 1.2e-05 25.0 0.2 1.3 1 0 0 1 1 1 1 U1 zinc finger TetR_C_6 PF13977.6 CRK40015.1 - 0.015 15.6 1.2 0.015 15.6 1.2 1.8 2 0 0 2 2 2 0 BetI-type transcriptional repressor, C-terminal adh_short PF00106.25 CRK40016.1 - 7.1e-26 90.9 0.0 2.7e-22 79.2 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CRK40016.1 - 9.6e-13 48.2 0.0 2.8e-11 43.4 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK40016.1 - 1.3e-10 41.5 0.0 1.9e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CRK40016.1 - 9.2e-06 25.3 0.1 1.4e-05 24.7 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Amidohydro_2 PF04909.14 CRK40016.1 - 0.0015 18.4 0.0 0.0044 16.9 0.0 1.8 2 0 0 2 2 2 1 Amidohydrolase Sacchrp_dh_NADP PF03435.18 CRK40016.1 - 0.0015 18.8 0.0 0.0033 17.7 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 CRK40016.1 - 0.0033 16.6 0.0 0.0048 16.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 CRK40016.1 - 0.016 15.3 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.24 CRK40016.1 - 0.11 12.9 0.1 0.32 11.4 0.0 1.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain PIR PF00399.19 CRK40017.1 - 2.4e-13 49.2 6.5 1.3e-06 27.8 0.9 2.6 2 0 0 2 2 2 2 Yeast PIR protein repeat Hce2 PF14856.6 CRK40018.1 - 5.5e-30 103.7 0.1 3.7e-14 52.8 0.0 2.6 2 0 0 2 2 2 2 Pathogen effector; putative necrosis-inducing factor Methyltransf_2 PF00891.18 CRK40020.1 - 1.5e-16 60.3 0.0 3.8e-16 59.0 0.0 1.6 1 1 0 1 1 1 1 O-methyltransferase domain Glyco_hydro_88 PF07470.13 CRK40022.1 - 6.9e-67 226.0 2.2 8.3e-67 225.7 2.2 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_hydro_127 PF07944.12 CRK40022.1 - 0.0045 15.5 0.0 0.0067 15.0 0.0 1.2 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 C5-epim_C PF06662.13 CRK40022.1 - 0.0078 15.7 0.7 0.21 11.1 0.0 2.7 2 1 1 3 3 3 1 D-glucuronyl C5-epimerase C-terminus Aldedh PF00171.22 CRK40028.1 - 8.4e-135 449.8 0.0 1.4e-134 449.1 0.0 1.3 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GMC_oxred_N PF00732.19 CRK40028.1 - 1e-35 123.6 0.0 1.4e-35 123.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase ADH_zinc_N PF00107.26 CRK40028.1 - 2.3e-24 85.8 1.3 5.5e-24 84.6 1.1 1.8 2 0 0 2 2 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CRK40028.1 - 5.9e-20 71.2 0.7 1.3e-19 70.1 0.7 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DAO PF01266.24 CRK40028.1 - 1.5e-05 24.8 0.0 0.00025 20.7 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 CRK40028.1 - 0.00046 19.3 0.0 0.00075 18.6 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 CRK40028.1 - 0.0028 17.8 0.4 0.02 15.1 0.2 2.7 2 1 1 3 3 2 1 NAD(P)-binding Rossmann-like domain LuxC PF05893.14 CRK40028.1 - 0.0062 15.6 0.0 0.0097 15.0 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Pyr_redox_2 PF07992.14 CRK40028.1 - 0.011 14.9 0.0 0.023 14.0 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CRK40028.1 - 0.014 14.5 0.0 0.041 13.0 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 CRK40028.1 - 0.025 13.3 0.0 0.038 12.7 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.6 CRK40028.1 - 0.041 13.9 0.0 0.1 12.6 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding ADH_zinc_N_2 PF13602.6 CRK40028.1 - 0.062 14.3 0.0 0.16 13.0 0.0 1.8 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Pyr_redox_3 PF13738.6 CRK40028.1 - 0.22 10.7 0.4 0.34 10.1 0.4 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CRK40028.1 - 0.22 10.8 0.7 0.4 10.0 0.5 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 CRK40028.1 - 4.6 6.5 8.8 0.11 11.7 2.1 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Peptidase_S8 PF00082.22 CRK40031.1 - 2.6e-35 122.1 0.0 7.5e-17 61.5 0.0 2.2 1 1 1 2 2 2 2 Subtilase family fn3_5 PF06280.12 CRK40031.1 - 5.3e-07 30.3 0.1 2.2e-06 28.3 0.0 2.1 2 0 0 2 2 2 1 Fn3-like domain Egh16-like PF11327.8 CRK40036.1 - 1e-50 172.7 7.6 1e-50 172.7 7.6 1.8 2 1 0 2 2 2 1 Egh16-like virulence factor API5 PF05918.11 CRK40036.1 - 0.089 11.6 5.5 0.13 11.1 5.5 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Izumo-Ig PF16706.5 CRK40036.1 - 0.21 11.6 0.0 0.43 10.7 0.0 1.4 1 0 0 1 1 1 0 Izumo-like Immunoglobulin domain Sugar_tr PF00083.24 CRK40038.1 - 6.8e-81 272.4 22.0 8.4e-81 272.1 22.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter DUF1264 PF06884.11 CRK40038.1 - 5.7e-76 253.9 0.0 9e-76 253.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) MFS_1 PF07690.16 CRK40038.1 - 2.6e-26 92.4 21.0 3.7e-26 91.9 21.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 CRK40038.1 - 2.9e-06 26.1 13.1 8.8e-06 24.5 3.4 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein PTR2 PF00854.21 CRK40038.1 - 0.00096 18.1 3.4 0.00096 18.1 3.4 2.1 2 0 0 2 2 2 1 POT family DUF4441 PF14536.6 CRK40038.1 - 0.061 13.5 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4441) TMEM240 PF15207.6 CRK40038.1 - 0.16 11.6 0.4 0.95 9.1 0.0 2.4 2 0 0 2 2 2 0 TMEM240 family Lipocalin_9 PF17186.4 CRK40039.1 - 0.15 12.3 0.5 0.38 11.0 0.5 1.7 1 0 0 1 1 1 0 Lipocalin-like domain DUF2755 PF10954.8 CRK40040.1 - 0.04 13.8 2.2 0.32 10.9 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2755) 1-cysPrx_C PF10417.9 CRK40041.1 - 0.14 12.0 3.0 4.4 7.2 0.0 2.9 3 0 0 3 3 3 0 C-terminal domain of 1-Cys peroxiredoxin Cupin_2 PF07883.11 CRK40043.1 - 2e-05 24.2 0.5 3.7e-05 23.3 0.5 1.4 1 0 0 1 1 1 1 Cupin domain Peptidase_M10_C PF08548.11 CRK40043.1 - 0.27 11.1 0.1 0.4 10.5 0.1 1.2 1 0 0 1 1 1 0 Peptidase M10 serralysin C terminal Fungal_trans_2 PF11951.8 CRK40044.1 - 1.5e-26 93.1 0.4 2.2e-26 92.6 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.19 CRK40044.1 - 5.3e-10 39.1 0.0 7.8e-09 35.2 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain CLIP_SPH_mas PF18398.1 CRK40044.1 - 0.2 12.1 0.1 0.2 12.1 0.1 2.6 3 0 0 3 3 3 0 Clip-domain serine protease homolog masquerade Lyase_aromatic PF00221.19 CRK40045.1 - 2.8e-149 497.8 7.4 3.1e-149 497.6 7.4 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase p450 PF00067.22 CRK40046.1 - 4.7e-66 223.4 0.0 5.9e-66 223.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AAA_2 PF07724.14 CRK40048.1 - 1.9e-45 155.1 0.0 2.9e-44 151.2 0.0 2.8 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 CRK40048.1 - 5.5e-31 106.6 6.8 4.3e-29 100.5 0.7 3.3 4 0 0 4 4 2 2 AAA lid domain AAA PF00004.29 CRK40048.1 - 1.5e-26 93.4 0.0 5.4e-14 52.7 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 CRK40048.1 - 3.5e-24 84.6 0.5 1.4e-23 82.7 0.5 2.2 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 CRK40048.1 - 8.3e-16 58.2 0.0 3.5e-10 40.0 0.0 3.3 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CRK40048.1 - 9.9e-13 48.5 0.0 3.8e-05 24.0 0.0 3.8 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CRK40048.1 - 4.6e-12 46.7 8.6 1.1e-06 29.1 0.1 5.2 4 3 1 6 6 4 2 AAA ATPase domain Sigma54_activat PF00158.26 CRK40048.1 - 5.5e-09 35.9 0.0 4.5e-06 26.5 0.0 2.8 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.6 CRK40048.1 - 1.6e-07 31.5 0.0 0.025 14.6 0.0 3.1 2 1 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 CRK40048.1 - 4.3e-07 30.1 0.3 0.014 15.3 0.2 4.1 2 2 2 4 4 4 1 ATPase domain predominantly from Archaea AAA_18 PF13238.6 CRK40048.1 - 1.5e-06 28.8 0.2 0.088 13.4 0.0 3.9 2 1 1 3 3 3 2 AAA domain IstB_IS21 PF01695.17 CRK40048.1 - 2.3e-06 27.5 0.0 0.051 13.3 0.0 2.9 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_7 PF12775.7 CRK40048.1 - 2.9e-06 26.9 0.0 0.014 14.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region Mg_chelatase PF01078.21 CRK40048.1 - 4e-06 26.4 0.0 0.25 10.7 0.0 3.5 2 1 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 CRK40048.1 - 1.5e-05 25.2 0.5 0.23 11.6 0.0 3.3 3 1 0 3 3 2 2 AAA domain TniB PF05621.11 CRK40048.1 - 2.1e-05 24.0 0.1 1.6 8.1 0.0 4.2 3 2 1 4 4 4 1 Bacterial TniB protein Clp_N PF02861.20 CRK40048.1 - 2.3e-05 24.4 4.5 0.00087 19.4 0.4 3.6 3 0 0 3 3 3 1 Clp amino terminal domain, pathogenicity island component AAA_28 PF13521.6 CRK40048.1 - 4.1e-05 23.9 0.0 0.39 11.0 0.0 3.2 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 CRK40048.1 - 5.1e-05 23.1 0.0 0.77 9.4 0.0 3.2 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.22 CRK40048.1 - 6.1e-05 23.4 0.0 0.47 10.9 0.0 2.6 2 0 0 2 2 2 2 RNA helicase RsgA_GTPase PF03193.16 CRK40048.1 - 7.6e-05 22.7 0.0 0.073 13.0 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase AAA_3 PF07726.11 CRK40048.1 - 0.00017 21.4 0.0 0.66 9.8 0.0 3.7 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 CRK40048.1 - 0.00017 21.9 0.2 0.071 13.4 0.1 3.5 4 1 0 4 4 2 1 AAA domain AAA_24 PF13479.6 CRK40048.1 - 0.00027 20.7 0.2 0.53 10.0 0.0 3.3 3 1 0 3 3 3 1 AAA domain TsaE PF02367.17 CRK40048.1 - 0.00036 20.5 0.0 0.51 10.3 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 CRK40048.1 - 0.00039 20.2 2.0 3.4 7.4 0.9 4.3 3 1 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain ABC_tran PF00005.27 CRK40048.1 - 0.00041 20.9 0.0 0.77 10.3 0.0 3.0 3 0 0 3 3 2 1 ABC transporter AAA_23 PF13476.6 CRK40048.1 - 0.0018 18.8 0.0 0.37 11.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 CRK40048.1 - 0.0021 17.2 0.0 0.036 13.1 0.0 2.6 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_29 PF13555.6 CRK40048.1 - 0.0022 17.7 0.0 2.8 7.7 0.0 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain Zeta_toxin PF06414.12 CRK40048.1 - 0.0029 16.9 0.0 0.54 9.5 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin NACHT PF05729.12 CRK40048.1 - 0.0039 17.1 0.0 0.31 11.0 0.0 2.7 3 0 0 3 3 2 1 NACHT domain ResIII PF04851.15 CRK40048.1 - 0.005 16.9 0.0 0.86 9.6 0.0 3.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Roc PF08477.13 CRK40048.1 - 0.0055 16.9 0.0 2 8.6 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_25 PF13481.6 CRK40048.1 - 0.0074 15.9 0.7 1.8 8.1 0.0 3.4 3 0 0 3 3 3 1 AAA domain Rad17 PF03215.15 CRK40048.1 - 0.0078 16.2 0.0 5.1 7.0 0.0 2.8 2 0 0 2 2 2 0 Rad17 P-loop domain Torsin PF06309.11 CRK40048.1 - 0.0094 16.0 0.0 0.052 13.7 0.0 2.1 2 0 0 2 2 2 1 Torsin NTPase_1 PF03266.15 CRK40048.1 - 0.01 15.7 0.0 0.26 11.2 0.0 2.7 2 0 0 2 2 2 0 NTPase SRP54 PF00448.22 CRK40048.1 - 0.015 14.9 0.0 3.5 7.2 0.0 2.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_11 PF13086.6 CRK40048.1 - 0.025 14.4 2.2 4.6 6.9 0.0 3.4 3 1 1 4 4 4 0 AAA domain AAA_21 PF13304.6 CRK40048.1 - 0.039 13.8 0.0 13 5.4 0.0 3.2 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF815 PF05673.13 CRK40048.1 - 0.039 13.1 0.0 2.7 7.1 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF815) Cytidylate_kin PF02224.18 CRK40048.1 - 0.061 13.0 1.6 40 3.8 0.0 3.9 4 0 0 4 4 3 0 Cytidylate kinase Parvo_NS1 PF01057.17 CRK40048.1 - 0.097 11.7 0.0 6.9 5.7 0.0 2.8 3 0 0 3 3 3 0 Parvovirus non-structural protein NS1 ATP_bind_1 PF03029.17 CRK40048.1 - 0.11 12.2 0.0 11 5.7 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 CRK40048.1 - 0.12 12.1 0.0 6.6 6.5 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Mhr1 PF12829.7 CRK40049.1 - 6.8e-33 112.6 0.1 1e-32 112.0 0.1 1.3 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination Acetyltransf_3 PF13302.7 CRK40050.1 - 1e-07 32.7 0.0 1.3e-07 32.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CRK40050.1 - 0.0031 17.7 0.1 0.0059 16.8 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family GNAT_acetyltran PF12746.7 CRK40050.1 - 0.2 11.2 0.0 0.27 10.8 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase Hexokinase_2 PF03727.16 CRK40063.1 - 1.9e-28 99.5 0.1 1.9e-28 99.5 0.1 2.1 3 0 0 3 3 3 1 Hexokinase MFS_5 PF05631.14 CRK40063.1 - 4.5e-26 91.6 0.9 6.7e-26 91.0 0.9 1.3 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 CRK40063.1 - 8.8e-08 31.5 10.7 8.8e-08 31.5 10.7 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Ribosomal_S11 PF00411.19 CRK40063.1 - 0.14 12.6 0.5 0.36 11.2 0.1 1.9 2 0 0 2 2 2 0 Ribosomal protein S11 DUF4231 PF14015.6 CRK40063.1 - 2.5 8.6 8.8 5.7 7.5 2.2 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF4231) Acetyltransf_1 PF00583.25 CRK40065.1 - 1.4e-05 25.3 0.0 1.8e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CRK40065.1 - 0.075 13.5 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MFS_1 PF07690.16 CRK40095.1 - 5.2e-35 121.0 51.4 5.2e-35 121.0 51.4 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Pro_isomerase PF00160.21 CRK40117.1 - 1.2e-12 48.4 0.0 1.3e-12 48.3 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Abhydrolase_9 PF10081.9 CRK40131.1 - 0.075 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta-hydrolase family MFS_1 PF07690.16 CRK40140.1 - 2.7e-15 56.1 25.6 2.7e-15 56.1 25.6 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily GHMP_kinases_N PF00288.26 CRK40140.1 - 4.2e-12 46.1 1.1 1.6e-11 44.3 1.1 2.0 1 0 0 1 1 1 1 GHMP kinases N terminal domain Proteasome PF00227.26 CRK40144.1 - 2.9e-11 43.2 0.1 3.2e-11 43.1 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit CMV_1a PF12467.8 CRK40156.1 - 0.11 12.8 1.8 0.14 12.5 1.8 1.2 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family DSS1_SEM1 PF05160.13 CRK40157.1 - 4e-21 74.8 14.3 4.4e-21 74.7 14.3 1.0 1 0 0 1 1 1 1 DSS1/SEM1 family ArfGap PF01412.18 CRK40157.1 - 0.15 12.2 0.7 0.17 12.0 0.7 1.1 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf Abhydrolase_1 PF00561.20 CRK40160.1 - 3.8e-09 36.6 0.0 1.1e-08 35.1 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CRK40160.1 - 3.6e-05 23.2 0.0 0.003 16.9 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Med19 PF10278.9 CRK40160.1 - 0.014 15.3 0.9 0.014 15.3 0.9 2.0 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 Aldo_ket_red PF00248.21 CRK40161.1 - 1.2e-18 67.3 0.0 5.6e-17 61.9 0.0 2.1 1 1 0 1 1 1 1 Aldo/keto reductase family FA_hydroxylase PF04116.13 CRK40161.1 - 7.9e-11 42.4 1.1 7.9e-11 42.4 1.1 2.3 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily UDPGT PF00201.18 CRK40161.1 - 0.14 10.9 0.0 0.2 10.4 0.0 1.1 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase Myb_DNA-binding PF00249.31 CRK40168.1 - 5.1e-34 116.2 9.5 4.3e-16 58.8 0.5 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CRK40168.1 - 1.6e-27 95.5 7.6 4.7e-15 55.6 0.9 3.3 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 CRK40168.1 - 3.6e-09 36.4 0.8 0.00039 20.3 0.0 2.6 2 0 0 2 2 2 2 Myb DNA-binding like SANT_DAMP1_like PF16282.5 CRK40168.1 - 1.4e-06 28.4 0.6 0.041 14.1 0.1 2.7 2 1 1 3 3 3 2 SANT/Myb-like domain of DAMP1 MADF_DNA_bdg PF10545.9 CRK40168.1 - 0.0046 17.3 3.8 1.4 9.2 0.5 2.4 2 0 0 2 2 2 2 Alcohol dehydrogenase transcription factor Myb/SANT-like SLIDE PF09111.10 CRK40168.1 - 0.053 13.5 0.1 12 5.9 0.0 2.5 1 1 1 2 2 2 0 SLIDE Methyltransf_2 PF00891.18 CRK40169.1 - 2.1e-23 82.8 0.0 1.1e-21 77.1 0.0 2.8 1 1 0 2 2 2 1 O-methyltransferase domain Sulfotransfer_4 PF17784.1 CRK40169.1 - 0.031 14.1 0.0 0.062 13.1 0.0 1.5 1 0 0 1 1 1 0 Sulfotransferase domain Dimerisation2 PF16864.5 CRK40169.1 - 0.036 14.0 0.0 0.13 12.2 0.0 1.9 2 0 0 2 2 2 0 Dimerisation domain FAD_binding_3 PF01494.19 CRK40170.1 - 1.4e-65 221.9 0.0 7.1e-65 219.5 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 CRK40170.1 - 0.0023 18.1 0.0 0.008 16.4 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 CRK40170.1 - 0.0036 16.4 0.2 0.051 12.6 0.1 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.17 CRK40170.1 - 0.004 16.4 0.0 0.0067 15.7 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 CRK40170.1 - 0.005 16.1 0.0 0.01 15.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CRK40170.1 - 0.012 15.3 0.5 0.09 12.3 0.5 2.3 1 1 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 CRK40170.1 - 0.012 14.3 0.1 0.017 13.8 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.24 CRK40170.1 - 0.013 14.6 1.7 0.017 14.2 0.3 1.8 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.6 CRK40170.1 - 0.014 14.7 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Phe_hydrox_dim PF07976.12 CRK40170.1 - 0.017 15.2 0.0 0.029 14.4 0.0 1.4 1 0 0 1 1 1 0 Phenol hydroxylase, C-terminal dimerisation domain FAD_oxidored PF12831.7 CRK40170.1 - 0.026 13.9 0.5 0.038 13.3 0.1 1.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 CRK40170.1 - 0.067 13.7 0.0 0.16 12.6 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Abhydrolase_1 PF00561.20 CRK40172.1 - 0.0023 17.6 0.0 0.01 15.5 0.0 1.8 1 1 0 2 2 2 1 alpha/beta hydrolase fold DUF676 PF05057.14 CRK40172.1 - 0.0029 17.1 0.0 0.0037 16.8 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 CRK40172.1 - 0.017 14.4 0.0 0.15 11.3 0.0 2.0 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 CRK40172.1 - 0.058 13.2 0.1 0.23 11.2 0.1 1.8 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase PhoLip_ATPase_C PF16212.5 CRK40182.1 - 5.7e-08 32.8 1.4 6.1e-08 32.7 1.4 1.0 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal DUF751 PF05421.11 CRK40182.1 - 0.23 12.2 3.8 0.79 10.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF751) AA_kinase PF00696.28 CRK40183.1 - 5.9e-32 111.2 0.0 1.1e-31 110.3 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family NAT PF04768.13 CRK40183.1 - 5.4e-19 68.5 0.0 2.3e-18 66.4 0.0 2.0 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Titin_Z PF09042.11 CRK40183.1 - 0.47 10.4 3.8 3.8 7.6 0.1 2.5 2 0 0 2 2 2 0 Titin Z Isy1 PF06246.12 CRK40184.1 - 3.8e-38 131.5 3.6 3.7e-37 128.3 0.2 2.0 1 1 1 2 2 2 2 Isy1-like splicing family DUF5103 PF17116.5 CRK40184.1 - 0.11 11.8 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5103) DUF456 PF04306.13 CRK40192.1 - 0.0022 18.3 0.9 0.0032 17.8 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF456) PNP_UDP_1 PF01048.20 CRK40193.1 - 0.056 12.7 0.0 0.065 12.5 0.0 1.1 1 0 0 1 1 1 0 Phosphorylase superfamily Sugar_tr PF00083.24 CRK40195.1 - 1.2e-63 215.6 18.8 1.6e-63 215.2 18.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter HsbA PF12296.8 CRK40195.1 - 5.8e-19 68.7 14.7 1.7e-18 67.2 13.1 2.2 2 0 0 2 2 2 1 Hydrophobic surface binding protein A MFS_1 PF07690.16 CRK40195.1 - 4.9e-12 45.4 27.6 9.5e-12 44.5 27.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Pec_lyase_C PF00544.19 CRK40197.1 - 1e-39 136.3 6.2 1.5e-39 135.8 6.2 1.2 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 CRK40197.1 - 0.00021 21.2 8.6 0.0025 17.7 8.6 2.3 1 1 0 1 1 1 1 Right handed beta helix region Cation_ATPase_C PF00689.21 CRK40198.1 - 1.4e-45 155.2 7.3 1.4e-45 155.2 7.3 2.2 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 CRK40198.1 - 3.4e-37 127.7 0.6 3.4e-37 127.7 0.6 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 CRK40198.1 - 6.5e-22 78.8 0.6 1.5e-21 77.6 0.6 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CRK40198.1 - 1e-21 76.8 0.0 2e-21 75.8 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 CRK40198.1 - 8.9e-13 47.7 0.0 9.7e-10 38.0 0.0 2.8 2 0 0 2 2 2 2 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CRK40198.1 - 0.00048 19.9 0.3 0.00091 19.0 0.3 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF3899 PF13038.6 CRK40198.1 - 0.085 13.4 0.0 0.085 13.4 0.0 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF3899) LptF_LptG PF03739.14 CRK40198.1 - 2.6 6.8 9.7 0.12 11.1 3.5 1.9 2 0 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG TctB PF07331.11 CRK40198.1 - 7.8 6.8 11.1 6 7.1 1.8 3.7 3 0 0 3 3 3 0 Tripartite tricarboxylate transporter TctB family MFS_1 PF07690.16 CRK40201.1 - 9.9e-33 113.5 80.7 7.9e-21 74.4 45.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily CFEM PF05730.11 CRK40202.1 - 0.012 15.7 20.1 0.14 12.3 1.8 3.5 3 0 0 3 3 3 0 CFEM domain TAFA PF12020.8 CRK40202.1 - 0.016 15.7 0.2 0.047 14.2 0.2 1.8 1 0 0 1 1 1 0 TAFA family Gram_pos_anchor PF00746.21 CRK40202.1 - 0.026 14.5 0.7 0.026 14.5 0.7 2.6 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Syndecan PF01034.20 CRK40202.1 - 0.31 11.0 0.6 0.57 10.1 0.6 1.4 1 0 0 1 1 1 0 Syndecan domain PTP_tm PF18861.1 CRK40202.1 - 0.39 10.7 4.6 0.68 9.9 4.6 1.3 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J TraL PF07178.11 CRK40205.1 - 0.22 12.0 4.6 6.3 7.3 0.0 3.5 3 2 0 3 3 3 0 TraL protein FAD_binding_4 PF01565.23 CRK40206.1 - 1.9e-18 66.6 1.9 1.9e-18 66.6 1.9 1.6 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 CRK40206.1 - 9.3e-06 25.6 0.0 1.7e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like Methyltransf_11 PF08241.12 CRK40207.1 - 4.2e-07 30.5 0.0 1e-06 29.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK40207.1 - 1.8e-05 24.6 0.0 3.2e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK40207.1 - 3.6e-05 24.4 0.0 0.00014 22.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Zn_clus PF00172.18 CRK40207.1 - 0.00059 19.9 0.4 0.0011 19.1 0.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 CRK40207.1 - 0.00087 18.2 0.0 0.0013 17.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_12 PF08242.12 CRK40207.1 - 0.021 15.5 0.0 0.049 14.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Egh16-like PF11327.8 CRK40208.1 - 6.6e-50 170.1 9.5 8.5e-50 169.7 9.5 1.1 1 0 0 1 1 1 1 Egh16-like virulence factor MFS_1 PF07690.16 CRK40209.1 - 1.1e-44 152.8 15.6 1.1e-44 152.8 15.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK40209.1 - 5e-16 58.6 0.1 5e-16 58.6 0.1 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 CRK40209.1 - 1.3e-05 23.7 2.8 3.3e-05 22.4 2.5 1.8 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Gly_kinase PF02595.15 CRK40210.1 - 2.5e-52 178.1 0.0 6.9e-29 101.0 0.0 2.0 1 1 1 2 2 2 2 Glycerate kinase family 5_nucleotid_C PF02872.18 CRK40211.1 - 3.6e-39 134.5 0.0 6.6e-39 133.7 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 CRK40211.1 - 2.2e-05 25.1 0.1 3.9e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase CTP_transf_1 PF01148.20 CRK40212.1 - 1.8e-79 267.3 24.3 2.6e-79 266.8 24.3 1.2 1 0 0 1 1 1 1 Cytidylyltransferase family Glyco_hydro_3_C PF01915.22 CRK40212.1 - 1.1e-54 185.5 0.0 2.7e-54 184.2 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 CRK40212.1 - 4.1e-54 184.1 0.0 6.5e-54 183.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 CRK40212.1 - 8.1e-22 77.1 0.2 1.6e-21 76.2 0.2 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain SnoaL_2 PF12680.7 CRK40212.1 - 2.7e-05 24.8 1.6 5e-05 23.9 0.1 2.3 2 0 0 2 2 2 1 SnoaL-like domain SnoaL PF07366.12 CRK40212.1 - 3.2e-05 23.7 0.1 6.5e-05 22.7 0.1 1.5 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase PA14 PF07691.12 CRK40212.1 - 0.00061 19.6 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 PA14 domain DUF3636 PF12331.8 CRK40215.1 - 1e-39 135.7 0.7 1.8e-39 134.9 0.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) DUF812 PF05667.11 CRK40215.1 - 0.0064 15.4 1.9 0.0094 14.9 1.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) TMF_TATA_bd PF12325.8 CRK40215.1 - 0.02 15.1 7.2 0.038 14.2 7.2 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding LCD1 PF09798.9 CRK40215.1 - 0.021 13.4 0.2 0.45 9.0 0.0 2.2 2 0 0 2 2 2 0 DNA damage checkpoint protein K-box PF01486.17 CRK40215.1 - 0.2 11.9 4.9 0.15 12.2 2.6 1.9 2 0 0 2 2 2 0 K-box region DUF3584 PF12128.8 CRK40215.1 - 4.8 4.6 11.0 7 4.0 11.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4407 PF14362.6 CRK40215.1 - 9.9 5.4 12.7 19 4.5 12.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3602 PF12223.8 CRK40217.1 - 0.023 15.3 0.3 0.024 15.2 0.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3602) p450 PF00067.22 CRK40219.1 - 6.7e-06 25.1 0.0 7.5e-06 24.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CRAL_TRIO PF00650.20 CRK40220.1 - 2.7e-38 131.2 0.0 7e-38 129.8 0.0 1.6 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CRK40220.1 - 1.1e-14 54.3 1.6 1.7e-14 53.7 0.2 2.1 2 1 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 CRK40220.1 - 8.4e-08 32.5 0.0 1.2e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DNA_pol_A_exoN PF18305.1 CRK40220.1 - 0.14 12.5 0.1 0.33 11.3 0.1 1.7 1 0 0 1 1 1 0 3' to 5' exonuclease C-terminal domain Fungal_trans_2 PF11951.8 CRK40221.1 - 4.2e-06 25.8 0.2 2.8e-05 23.1 0.2 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain HTH_16 PF12645.7 CRK40221.1 - 0.16 12.0 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Sulfate_transp PF00916.20 CRK40222.1 - 9.8e-68 228.6 12.8 5.1e-47 160.4 3.3 2.2 2 0 0 2 2 2 2 Sulfate permease family STAS PF01740.21 CRK40222.1 - 1.5e-15 56.8 0.0 2.8e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 CRK40222.1 - 0.011 16.2 2.1 0.011 16.2 2.1 2.5 3 0 0 3 3 3 0 Molybdate transporter of MFS superfamily DUF1282 PF06930.12 CRK40222.1 - 0.34 10.7 0.0 0.34 10.7 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1282) DUF485 PF04341.12 CRK40222.1 - 2.2 8.3 7.1 0.94 9.5 0.9 2.9 2 0 0 2 2 2 0 Protein of unknown function, DUF485 Glyco_hydro_cc PF11790.8 CRK40223.1 - 6e-64 215.9 0.1 7e-64 215.7 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Fip1 PF05182.13 CRK40223.1 - 0.00026 20.5 2.0 0.00026 20.5 2.0 1.8 2 0 0 2 2 2 1 Fip1 motif Sulfate_transp PF00916.20 CRK40224.1 - 4.9e-76 256.0 7.3 4.9e-76 256.0 7.3 1.3 1 1 0 1 1 1 1 Sulfate permease family STAS PF01740.21 CRK40224.1 - 1.3e-15 57.0 0.0 2.4e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 CRK40224.1 - 0.0037 17.7 3.9 0.0037 17.7 3.9 2.7 3 0 0 3 3 3 1 Molybdate transporter of MFS superfamily STAS_2 PF13466.6 CRK40224.1 - 0.032 14.6 0.0 0.093 13.1 0.0 1.8 1 0 0 1 1 1 0 STAS domain DUF485 PF04341.12 CRK40224.1 - 0.044 13.7 5.0 0.1 12.5 0.3 3.2 2 0 0 2 2 2 0 Protein of unknown function, DUF485 DUF1282 PF06930.12 CRK40224.1 - 0.074 12.8 8.3 0.4 10.4 0.0 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF1282) Thiolase_N PF00108.23 CRK40225.1 - 7.5e-61 205.8 3.5 1.1e-60 205.2 3.5 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CRK40225.1 - 1e-41 141.4 0.5 1e-41 141.4 0.5 2.4 3 0 0 3 3 3 1 Thiolase, C-terminal domain Glyco_hydro_cc PF11790.8 CRK40226.1 - 1.6e-63 214.4 0.1 1.9e-63 214.2 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Fip1 PF05182.13 CRK40226.1 - 0.00034 20.1 2.5 0.00034 20.1 2.5 1.8 2 0 0 2 2 2 1 Fip1 motif TFIIIC_delta PF12657.7 CRK40229.1 - 0.013 15.4 0.0 2.1 8.2 0.0 2.4 2 0 0 2 2 2 0 Transcription factor IIIC subunit delta N-term Paz_1 PF18349.1 CRK40229.1 - 0.013 15.4 0.1 7.8 6.5 0.0 2.3 2 0 0 2 2 2 0 PAZ domain tRNA-synt_1_2 PF13603.6 CRK40229.1 - 0.17 11.4 0.0 18 4.8 0.0 2.2 2 0 0 2 2 2 0 Leucyl-tRNA synthetase, Domain 2 DUF2496 PF10689.9 CRK40229.1 - 0.22 11.4 0.1 30 4.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2496) SIR2 PF02146.17 CRK40230.1 - 1.2e-31 110.0 0.0 1.1e-09 38.4 0.0 3.5 3 0 0 3 3 3 3 Sir2 family SIR2 PF02146.17 CRK40231.1 - 1.5e-31 109.7 0.0 1.1e-09 38.5 0.0 3.3 3 0 0 3 3 3 3 Sir2 family Na_H_Exchanger PF00999.21 CRK40233.1 - 1.3e-30 106.5 39.1 2e-30 105.9 39.1 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Fst_toxin PF13955.6 CRK40233.1 - 0.049 13.6 1.1 0.14 12.1 1.1 1.9 1 0 0 1 1 1 0 Toxin Fst, type I toxin-antitoxin system E1-E2_ATPase PF00122.20 CRK40234.1 - 9.5e-15 54.6 0.0 2.3e-14 53.3 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 CRK40234.1 - 6.1e-14 52.8 2.1 9.4e-08 32.6 2.5 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CRK40234.1 - 6.9e-05 22.9 0.0 0.00029 20.9 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CRK40234.1 - 0.0032 17.2 0.3 0.057 13.1 0.1 2.7 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Ldh_1_C PF02866.18 CRK40235.1 - 1e-24 87.3 0.0 1.2e-24 87.2 0.0 1.0 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain zf-C2HC5 PF06221.13 CRK40237.1 - 3.7e-20 71.7 5.4 5.7e-20 71.1 5.4 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Tropomodulin PF03250.14 CRK40237.1 - 0.045 13.8 0.1 0.14 12.3 0.1 1.7 2 0 0 2 2 2 0 Tropomodulin Whi5 PF08528.11 CRK40238.1 - 2.6e-11 42.9 0.0 4.5e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Whi5 like Rick_17kDa_Anti PF05433.15 CRK40239.1 - 5.1e-06 26.2 10.7 1.2e-05 25.1 10.7 1.7 1 0 0 1 1 1 1 Glycine zipper 2TM domain DUF1269 PF06897.12 CRK40239.1 - 0.047 14.0 1.2 0.093 13.0 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) Gly-zipper_YMGG PF13441.6 CRK40239.1 - 0.34 10.7 11.1 0.79 9.5 11.1 1.7 1 0 0 1 1 1 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 CRK40239.1 - 0.79 9.8 15.5 3.4 7.7 15.1 2.2 1 1 1 2 2 2 0 Glycine zipper Aminotran_5 PF00266.19 CRK40241.1 - 7.1e-18 64.7 0.0 3.2e-17 62.5 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class-V Asp PF00026.23 CRK40242.1 - 1.7e-61 208.4 2.5 2.1e-61 208.1 2.5 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CRK40242.1 - 2e-07 31.4 0.2 0.0077 16.5 0.0 2.6 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 CRK40242.1 - 0.002 17.9 0.1 0.0047 16.7 0.1 1.6 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 CRK40242.1 - 0.0062 17.1 2.5 0.18 12.4 0.3 3.5 3 1 0 3 3 3 1 Aspartyl protease gag-asp_proteas PF13975.6 CRK40242.1 - 1.1 9.9 3.0 3.8 8.1 0.2 3.2 3 1 0 3 3 3 0 gag-polyprotein putative aspartyl protease Myb_DNA-bind_3 PF12776.7 CRK40245.1 - 1.6e-25 89.9 0.7 1.6e-25 89.9 0.7 2.4 2 0 0 2 2 1 1 Myb/SANT-like DNA-binding domain EIF4E-T PF10477.9 CRK40245.1 - 0.00072 18.5 10.6 0.00095 18.1 10.6 1.1 1 0 0 1 1 1 1 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E MCU PF04678.13 CRK40245.1 - 0.017 15.2 3.0 0.037 14.1 3.0 1.5 1 0 0 1 1 1 0 Mitochondrial calcium uniporter DUF4407 PF14362.6 CRK40245.1 - 0.024 14.0 4.1 0.038 13.3 4.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Neur_chan_memb PF02932.16 CRK40245.1 - 0.038 14.0 3.4 0.055 13.5 3.4 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region EPL1 PF10513.9 CRK40245.1 - 0.041 14.3 4.4 0.08 13.3 4.4 1.5 1 0 0 1 1 1 0 Enhancer of polycomb-like Spt20 PF12090.8 CRK40245.1 - 0.15 11.7 33.6 0.25 10.9 33.6 1.3 1 0 0 1 1 1 0 Spt20 family Presenilin PF01080.17 CRK40245.1 - 0.19 10.5 8.5 0.26 10.0 8.5 1.2 1 0 0 1 1 1 0 Presenilin TERB2 PF15101.6 CRK40245.1 - 0.22 11.6 13.0 0.48 10.4 13.0 1.5 1 0 0 1 1 1 0 Telomere-associated protein TERB2 CPSF100_C PF13299.6 CRK40245.1 - 0.25 11.5 5.3 0.56 10.4 5.3 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal RR_TM4-6 PF06459.12 CRK40245.1 - 0.27 11.0 6.8 0.53 10.1 6.8 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SpoIIP PF07454.11 CRK40245.1 - 0.41 10.1 9.1 0.62 9.5 9.1 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Endostatin PF06482.11 CRK40245.1 - 0.91 8.9 12.3 1.6 8.1 12.3 1.3 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin PAT1 PF09770.9 CRK40245.1 - 1.1 7.5 26.5 1.4 7.1 26.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Band_3_cyto PF07565.13 CRK40245.1 - 1.9 8.2 7.3 3.2 7.5 7.3 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain eIF-3_zeta PF05091.12 CRK40245.1 - 3 6.7 13.5 4.3 6.2 13.5 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Hid1 PF12722.7 CRK40245.1 - 4.1 5.4 8.7 5.1 5.1 8.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MAJIN PF15077.6 CRK40245.1 - 5 6.9 10.8 9.5 5.9 10.8 1.4 1 0 0 1 1 1 0 Membrane-anchored junction protein UPF0560 PF10577.9 CRK40245.1 - 5.5 5.4 20.4 8.1 4.8 20.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF719 PF05334.13 CRK40245.1 - 6.7 6.9 10.7 9.4 6.4 8.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF719) Roughex PF06020.11 CRK40245.1 - 8.3 5.4 15.3 15 4.5 15.3 1.4 1 0 0 1 1 1 0 Drosophila roughex protein CHCH PF06747.13 CRK40248.1 - 2.1e-05 24.5 3.3 3.4e-05 23.9 3.3 1.3 1 0 0 1 1 1 1 CHCH domain LEA_4 PF02987.16 CRK40248.1 - 6.9e-05 22.8 12.9 0.00014 21.8 12.9 1.6 1 0 0 1 1 1 1 Late embryogenesis abundant protein YtxH PF12732.7 CRK40248.1 - 0.0093 16.5 10.0 0.027 15.0 10.0 1.8 1 0 0 1 1 1 1 YtxH-like protein GCK PF07802.11 CRK40248.1 - 1.4 9.4 6.9 0.15 12.5 0.8 2.4 2 1 0 2 2 2 0 GCK domain eIF-3c_N PF05470.12 CRK40248.1 - 2 6.6 10.4 2.8 6.2 10.4 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF5352 PF17303.2 CRK40248.1 - 9.8 6.0 8.0 7.1 6.4 5.6 1.7 1 1 1 2 2 2 0 Family of unknown function (DUF5352) TPK_catalytic PF04263.16 CRK40249.1 - 1.1e-29 103.0 0.0 1.6e-29 102.4 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 CRK40249.1 - 4.8e-22 77.4 0.2 9.5e-22 76.5 0.2 1.5 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain V-SNARE_C PF12352.8 CRK40251.1 - 2.3e-14 53.4 0.9 4.3e-14 52.5 0.1 1.9 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 CRK40251.1 - 0.0003 20.6 0.0 0.0014 18.5 0.0 1.9 2 0 0 2 2 2 1 Sec20 Sigma70_r4 PF04545.16 CRK40251.1 - 0.0048 16.4 0.0 0.014 14.9 0.0 1.8 1 0 0 1 1 1 1 Sigma-70, region 4 KxDL PF10241.9 CRK40251.1 - 0.0066 16.7 0.3 3.9 7.8 0.1 2.5 2 0 0 2 2 2 2 Uncharacterized conserved protein Flagellin_N PF00669.20 CRK40251.1 - 0.074 13.2 1.3 0.15 12.2 0.4 1.8 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region TPR_MLP1_2 PF07926.12 CRK40251.1 - 0.079 13.0 2.5 0.5 10.4 0.7 2.3 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DivIC PF04977.15 CRK40251.1 - 0.47 10.2 2.8 3 7.7 0.1 3.0 2 1 1 3 3 3 0 Septum formation initiator SAD_SRA PF02182.17 CRK40253.1 - 8.1e-35 119.8 0.0 1.1e-34 119.3 0.0 1.2 1 0 0 1 1 1 1 SAD/SRA domain Glyco_hydro_10 PF00331.20 CRK40255.1 - 1.5e-94 316.7 0.0 1.7e-94 316.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 DUF3037 PF11236.8 CRK40257.1 - 0.53 10.7 3.5 1.8 9.0 0.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3037) DUF5082 PF16888.5 CRK40257.1 - 0.54 10.5 5.7 4.9 7.4 0.3 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) DUF4407 PF14362.6 CRK40257.1 - 0.77 9.1 16.8 0.81 9.0 13.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) NPV_P10 PF05531.12 CRK40257.1 - 1.7 9.2 8.0 9.5 6.8 0.3 3.0 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF4201 PF13870.6 CRK40257.1 - 1.8 8.3 9.9 0.4 10.4 1.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) YlqD PF11068.8 CRK40257.1 - 2.3 8.6 8.0 1.6 9.1 0.9 2.5 2 0 0 2 2 2 0 YlqD protein DLH PF01738.18 CRK40258.1 - 4.2e-22 78.8 0.2 5.4e-22 78.4 0.2 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 CRK40258.1 - 0.086 12.5 0.0 0.23 11.1 0.0 1.7 1 1 1 2 2 2 0 alpha/beta hydrolase fold DEAD PF00270.29 CRK40259.1 - 5.3e-43 146.8 0.0 4.1e-41 140.7 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CRK40259.1 - 1.1e-10 41.9 0.0 1.5e-09 38.2 0.0 2.7 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 CRK40259.1 - 3.4e-06 27.2 0.0 7.4e-06 26.1 0.0 1.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 CRK40259.1 - 0.011 15.5 0.0 0.094 12.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain Helicase_C_2 PF13307.6 CRK40259.1 - 0.037 14.2 0.0 0.064 13.4 0.0 1.3 1 0 0 1 1 1 0 Helicase C-terminal domain AMP-binding PF00501.28 CRK40260.1 - 1.3e-55 188.8 0.0 2.4e-55 187.9 0.0 1.5 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CRK40260.1 - 4.9e-15 56.3 0.3 9.5e-15 55.4 0.3 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Peptidase_S10 PF00450.22 CRK40270.1 - 8.3e-78 262.6 2.1 1.1e-77 262.3 2.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.11 CRK40270.1 - 1.1e-16 61.5 4.7 3.3e-15 56.7 4.7 2.6 1 1 0 1 1 1 1 Carboxypeptidase Y pro-peptide Ribosomal_S13 PF00416.22 CRK40271.1 - 3e-36 124.7 1.5 3.4e-36 124.5 1.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 PP28 PF10252.9 CRK40271.1 - 0.12 12.9 0.2 0.2 12.1 0.2 1.4 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 tRNA-synt_1 PF00133.22 CRK40272.1 - 0.014 13.6 0.0 0.015 13.5 0.0 1.0 1 0 0 1 1 1 0 tRNA synthetases class I (I, L, M and V) Ribosomal_S8e PF01201.22 CRK40274.1 - 9.6e-12 45.2 3.2 1e-11 45.2 3.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e 2-Hacid_dh_C PF02826.19 CRK40276.1 - 9.1e-08 31.7 0.0 1e-07 31.5 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 CRK40276.1 - 0.012 16.0 0.0 0.015 15.7 0.0 1.1 1 0 0 1 1 1 0 Putative NAD(P)-binding ELFV_dehydrog PF00208.21 CRK40276.1 - 0.025 14.3 0.0 0.026 14.2 0.0 1.1 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Shikimate_DH PF01488.20 CRK40276.1 - 0.054 13.5 0.0 0.081 13.0 0.0 1.4 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase eIF-3_zeta PF05091.12 CRK40278.1 - 1.6e-138 463.0 0.0 2e-138 462.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Pkinase PF00069.25 CRK40280.1 - 1.6e-08 34.3 0.1 1.6e-08 34.2 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK40280.1 - 7.7e-06 25.4 0.1 7.8e-06 25.4 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase CAF1 PF04857.20 CRK40292.1 - 4e-11 42.6 0.0 6.1e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease NDUF_B12 PF08122.12 CRK40293.1 - 4.9e-24 84.1 1.0 6.6e-24 83.7 1.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family eIF-6 PF01912.18 CRK40295.1 - 3e-48 163.8 0.4 3.3e-48 163.7 0.4 1.0 1 0 0 1 1 1 1 eIF-6 family SDA1 PF05285.12 CRK40304.1 - 6.3e-91 305.4 46.2 6.3e-91 305.4 46.2 2.6 2 1 0 2 2 2 1 SDA1 NUC130_3NT PF08158.12 CRK40304.1 - 1.2e-22 80.0 0.1 2.6e-22 78.9 0.1 1.6 1 0 0 1 1 1 1 NUC130/3NT domain Dict-STAT-coil PF09267.10 CRK40304.1 - 0.048 14.0 1.9 0.29 11.5 0.1 2.8 2 0 0 2 2 2 0 Dictyostelium STAT, coiled coil Mito_carr PF00153.27 CRK40315.1 - 6.3e-34 115.8 0.1 1.1e-17 63.7 0.0 2.1 1 1 1 2 2 2 2 Mitochondrial carrier protein FoP_duplication PF13865.6 CRK40316.1 - 0.12 12.9 4.6 0.18 12.4 4.6 1.3 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 SH3BP5 PF05276.14 CRK40316.1 - 0.19 11.5 0.5 0.24 11.2 0.5 1.1 1 0 0 1 1 1 0 SH3 domain-binding protein 5 (SH3BP5) Cytochrom_B561 PF03188.16 CRK40329.1 - 8e-05 22.8 6.0 8e-05 22.8 6.0 1.6 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 YbjM PF11045.8 CRK40329.1 - 0.0085 16.2 1.3 0.014 15.5 1.3 1.3 1 0 0 1 1 1 1 Putative inner membrane protein of Enterobacteriaceae Collectrin PF16959.5 CRK40329.1 - 0.03 14.1 0.3 0.03 14.1 0.3 1.5 2 0 0 2 2 2 0 Renal amino acid transporter Insulin_TMD PF17870.1 CRK40329.1 - 0.042 13.9 1.4 1.4 9.0 0.1 2.6 3 0 0 3 3 3 0 Insulin receptor trans-membrane segment DUF3139 PF11337.8 CRK40329.1 - 0.054 14.2 1.2 0.38 11.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) DUF4079 PF13301.6 CRK40329.1 - 0.079 13.1 8.0 1.8 8.7 8.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) DoxX_3 PF13781.6 CRK40329.1 - 0.091 13.4 2.6 0.11 13.1 2.6 1.2 1 0 0 1 1 1 0 DoxX-like family MHYT PF03707.16 CRK40329.1 - 0.1 12.8 0.3 0.1 12.8 0.3 2.1 2 1 0 2 2 2 0 Bacterial signalling protein N terminal repeat NDUFA12 PF05071.16 CRK40335.1 - 0.051 14.4 0.0 0.053 14.4 0.0 1.1 1 0 0 1 1 1 0 NADH ubiquinone oxidoreductase subunit NDUFA12 Cellulase PF00150.18 CRK40350.1 - 1.4e-29 103.4 0.0 3.1e-29 102.3 0.0 1.5 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CRT10 PF08728.10 CRK40350.1 - 5.1e-13 48.1 0.0 4.3e-11 41.7 0.0 2.2 2 0 0 2 2 2 2 CRT10 RXT2_N PF08595.11 CRK40350.1 - 0.17 11.9 0.4 0.42 10.6 0.4 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF4611 PF15387.6 CRK40350.1 - 0.54 10.5 4.3 1.2 9.3 4.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) NOA36 PF06524.12 CRK40350.1 - 3.5 6.8 11.1 5.7 6.2 11.1 1.2 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 CRK40350.1 - 4.1 5.4 11.3 5.8 4.9 11.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi CENP-B_dimeris PF09026.10 CRK40350.1 - 5.7 7.4 16.2 18 5.8 16.2 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain BolA PF01722.18 CRK40354.1 - 2.6e-17 62.8 0.0 3.1e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein zf-C2H2 PF00096.26 CRK40354.1 - 0.25 11.9 0.4 9.7 6.9 0.1 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type GMC_oxred_C PF05199.13 CRK40366.1 - 1.8e-07 31.7 0.0 2.8e-07 31.1 0.0 1.4 1 1 0 1 1 1 1 GMC oxidoreductase RNA_pol_Rpc4 PF05132.14 CRK40366.1 - 0.036 14.5 4.7 0.055 13.9 4.7 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Jak1_Phl PF17887.1 CRK40366.1 - 0.04 13.9 6.4 0.056 13.4 6.4 1.3 1 0 0 1 1 1 0 Jak1 pleckstrin homology-like domain DUF3807 PF12720.7 CRK40366.1 - 0.05 13.9 10.5 0.068 13.4 10.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Presenilin PF01080.17 CRK40366.1 - 0.16 10.7 2.0 0.18 10.6 2.0 1.1 1 0 0 1 1 1 0 Presenilin EOS1 PF12326.8 CRK40366.1 - 0.21 11.5 0.5 0.22 11.4 0.5 1.1 1 0 0 1 1 1 0 N-glycosylation protein SR-25 PF10500.9 CRK40366.1 - 0.29 10.7 22.6 0.41 10.2 22.6 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Connexin PF00029.19 CRK40366.1 - 0.38 10.5 6.4 0.5 10.1 6.4 1.1 1 0 0 1 1 1 0 Connexin Red1 PF07964.11 CRK40366.1 - 1.7 6.8 18.9 2.2 6.4 18.9 1.0 1 0 0 1 1 1 0 Rec10 / Red1 EIIBC-GUT_N PF03612.14 CRK40366.1 - 2.7 7.7 7.9 3.9 7.2 7.9 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus RR_TM4-6 PF06459.12 CRK40366.1 - 3 7.6 11.1 4 7.2 11.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3464 PF11947.8 CRK40366.1 - 4.3 7.1 14.8 6.5 6.5 14.8 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Folate_carrier PF01770.18 CRK40366.1 - 5.7 5.6 5.9 7.5 5.2 5.9 1.1 1 0 0 1 1 1 0 Reduced folate carrier NPR3 PF03666.13 CRK40366.1 - 7.8 5.2 10.9 11 4.7 10.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 bZIP_1 PF00170.21 CRK40367.1 - 0.0013 18.8 7.7 0.0013 18.8 7.7 1.6 1 1 0 2 2 2 1 bZIP transcription factor T4SS PF07996.11 CRK40367.1 - 0.0045 17.4 4.6 0.0056 17.1 4.6 1.2 1 0 0 1 1 1 1 Type IV secretion system proteins SVIP PF15811.5 CRK40367.1 - 0.0049 17.3 5.1 0.0049 17.3 5.1 2.0 1 1 1 2 2 2 1 Small VCP/p97-interacting protein HSCB_C PF07743.13 CRK40367.1 - 0.23 12.0 5.0 0.35 11.4 5.0 1.3 1 0 0 1 1 1 0 HSCB C-terminal oligomerisation domain M PF02370.16 CRK40367.1 - 0.3 11.8 8.2 2.5 8.9 1.2 3.1 3 0 0 3 3 3 0 M protein repeat DUF1003 PF06210.11 CRK40367.1 - 0.89 9.7 2.7 1.3 9.1 2.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) Ribosomal_L37 PF08561.10 CRK40367.1 - 5.5 7.5 9.4 7.2 7.2 9.4 1.4 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L37 FAD_binding_4 PF01565.23 CRK40385.1 - 2.3e-36 124.6 0.1 5.1e-36 123.5 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 CRK40385.1 - 7.5e-35 120.8 0.2 1.3e-33 116.6 0.0 2.1 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain Aldose_epim PF01263.20 CRK40396.1 - 3.9e-07 29.7 0.0 7.2e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Aldose 1-epimerase Glyco_transf_90 PF05686.12 CRK40396.1 - 0.00075 18.5 0.1 0.031 13.2 0.0 2.6 2 1 0 2 2 2 1 Glycosyl transferase family 90 Tetraspanin PF00335.20 CRK40396.1 - 0.029 14.1 0.7 0.42 10.3 0.0 2.4 2 0 0 2 2 2 0 Tetraspanin family DHHC PF01529.20 CRK40397.1 - 3.2e-32 111.4 2.4 3.2e-32 111.4 2.4 1.5 2 0 0 2 2 2 1 DHHC palmitoyltransferase Myosin_head PF00063.21 CRK40398.1 - 3.9e-237 788.8 5.7 4.7e-237 788.5 5.7 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 CRK40398.1 - 3.2e-49 167.1 0.0 6.4e-49 166.2 0.0 1.5 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_1 PF00018.28 CRK40398.1 - 8.1e-15 54.2 0.6 1.6e-14 53.2 0.6 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CRK40398.1 - 1e-12 47.7 0.1 2.4e-12 46.5 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CRK40398.1 - 8.7e-11 41.3 0.1 1.9e-10 40.3 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain IQ PF00612.27 CRK40398.1 - 0.0046 16.6 10.0 0.17 11.8 2.4 2.8 1 1 1 2 2 2 2 IQ calmodulin-binding motif GCFC PF07842.12 CRK40398.1 - 0.0098 15.5 0.1 0.02 14.5 0.1 1.4 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein Hpr_kinase_C PF07475.12 CRK40398.1 - 0.012 15.2 0.3 5.2 6.6 0.1 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_22 PF13401.6 CRK40398.1 - 0.052 13.8 0.0 0.17 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CRK40398.1 - 0.058 13.8 0.0 0.17 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 CRK40398.1 - 0.13 12.1 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 NACHT domain DUF4913 PF16259.5 CRK40398.1 - 0.21 11.7 1.5 0.57 10.3 1.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4913) F-box-like PF12937.7 CRK40399.1 - 4.1e-10 39.4 0.3 1.4e-09 37.7 0.3 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CRK40399.1 - 2.3e-05 24.1 1.1 5.2e-05 23.0 0.4 2.0 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 CRK40399.1 - 0.1 12.5 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 F-box Big_2 PF02368.18 CRK40399.1 - 0.22 11.4 0.0 1.4 8.8 0.0 2.0 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 2) NAD_binding_6 PF08030.12 CRK40400.1 - 1.1e-22 80.9 0.0 1.7e-22 80.2 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 CRK40400.1 - 2.3e-22 79.1 0.0 4.6e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 CRK40400.1 - 6e-20 71.6 13.5 6.2e-20 71.6 10.1 2.2 1 1 1 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 CRK40400.1 - 0.17 12.6 0.0 3.7 8.2 0.0 2.2 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain WLM PF08325.10 CRK40401.1 - 2.9e-58 197.1 0.2 4.9e-58 196.4 0.2 1.4 1 0 0 1 1 1 1 WLM domain Response_reg PF00072.24 CRK40401.1 - 1.1e-22 80.3 0.2 2.1e-22 79.4 0.2 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 CRK40401.1 - 7.7e-14 52.2 0.0 1.6e-13 51.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase zf-RanBP PF00641.18 CRK40401.1 - 5.1e-05 22.5 0.5 0.00011 21.4 0.5 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others SWIRM-assoc_2 PF16496.5 CRK40402.1 - 0.021 13.7 0.2 0.021 13.7 0.2 4.3 3 1 2 5 5 5 0 SWIRM-associated domain at the N-terminal PLA2_B PF01735.18 CRK40403.1 - 3.5e-186 619.4 0.0 4.1e-186 619.2 0.0 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain RNA_pol_Rpb2_5 PF04567.17 CRK40404.1 - 0.14 12.7 3.3 16 6.1 0.3 2.9 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 5 MPM1 PF17234.2 CRK40404.1 - 5 7.3 24.0 2.2 8.5 6.9 2.4 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 MMR1 PF08505.10 CRK40404.1 - 6.1 7.1 49.0 1.9 8.8 17.0 2.4 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein DAHP_synth_2 PF01474.16 CRK40406.1 - 1.1e-202 673.3 0.0 1.3e-202 673.2 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family Glyco_hydro_18 PF00704.28 CRK40407.1 - 1e-61 209.4 0.0 9.6e-61 206.2 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Vps53_N PF04100.12 CRK40408.1 - 9e-49 166.4 0.0 1.6e-48 165.6 0.0 1.3 1 0 0 1 1 1 1 Vps53-like, N-terminal Herpes_capsid PF06112.11 CRK40408.1 - 0.099 12.7 3.4 0.2 11.7 3.4 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DUF2451 PF10474.9 CRK40408.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2451) Senescence PF06911.12 CRK40409.1 - 0.012 15.9 1.9 0.021 15.2 1.9 1.4 1 1 0 1 1 1 0 Senescence-associated protein VPS13_C PF16909.5 CRK40409.1 - 0.39 10.5 2.1 0.34 10.7 1.1 1.5 1 1 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal tRNA-synt_2 PF00152.20 CRK40410.1 - 2.5e-84 283.0 0.0 3.5e-84 282.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) YajC PF02699.15 CRK40410.1 - 0.14 12.1 0.0 0.44 10.4 0.0 1.8 2 0 0 2 2 2 0 Preprotein translocase subunit tRNA-synt_2b PF00587.25 CRK40410.1 - 0.16 12.0 0.1 0.25 11.3 0.1 1.3 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) Memo PF01875.17 CRK40411.1 - 6.3e-73 245.2 0.0 7.2e-73 245.1 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein Polyketide_cyc2 PF10604.9 CRK40411.1 - 0.14 12.4 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Senescence PF06911.12 CRK40412.1 - 0.009 16.3 2.3 0.014 15.7 2.3 1.3 1 1 0 1 1 1 1 Senescence-associated protein VPS13_C PF16909.5 CRK40412.1 - 0.78 9.5 2.4 0.61 9.9 1.2 1.5 1 1 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal tRNA-synt_2 PF00152.20 CRK40413.1 - 2.2e-113 378.5 0.0 6.2e-76 255.5 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 CRK40413.1 - 0.00092 19.2 0.5 0.36 10.8 0.1 2.3 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.20 CRK40413.1 - 0.075 12.5 1.4 20 4.6 0.1 3.4 4 0 0 4 4 4 0 tRNA synthetases class II core domain (F) YajC PF02699.15 CRK40413.1 - 0.12 12.3 0.0 0.4 10.6 0.0 1.8 2 0 0 2 2 2 0 Preprotein translocase subunit DUF4448 PF14610.6 CRK40414.1 - 2.6e-28 99.1 0.0 3.5e-28 98.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) EVI2A PF05399.11 CRK40415.1 - 0.0067 16.1 2.7 0.009 15.6 2.7 1.1 1 0 0 1 1 1 1 Ectropic viral integration site 2A protein (EVI2A) DUF4448 PF14610.6 CRK40416.1 - 7.6e-28 97.6 0.0 9.6e-28 97.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF3188 PF11384.8 CRK40416.1 - 0.11 12.2 0.0 0.3 10.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) Cyclin_N PF00134.23 CRK40418.1 - 6.9e-39 132.5 0.6 1.1e-38 131.9 0.2 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CRK40418.1 - 6.3e-11 42.4 0.1 2e-10 40.8 0.1 1.9 1 1 0 1 1 1 1 Cyclin, C-terminal domain Asp_protease_2 PF13650.6 CRK40419.1 - 0.00086 19.9 0.0 0.002 18.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CRK40419.1 - 0.0015 19.1 0.0 0.0033 18.0 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Cyclin_N PF00134.23 CRK40423.1 - 6.9e-39 132.5 0.6 1.1e-38 131.9 0.2 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CRK40423.1 - 6.3e-11 42.4 0.1 2e-10 40.8 0.1 1.9 1 1 0 1 1 1 1 Cyclin, C-terminal domain Asp_protease_2 PF13650.6 CRK40425.1 - 0.00091 19.8 0.0 0.0022 18.6 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CRK40425.1 - 0.0015 19.0 0.0 0.0033 18.0 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Glyco_hydro_18 PF00704.28 CRK40427.1 - 1.8e-17 64.1 0.0 2.1e-17 63.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 ADH_N PF08240.12 CRK40428.1 - 1e-08 35.0 0.4 4.1e-08 33.1 0.3 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CRK40428.1 - 7.4e-05 22.7 0.0 0.00013 22.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CRK40428.1 - 0.00018 22.6 0.0 0.0004 21.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 CRK40428.1 - 0.019 14.9 0.0 0.3 11.0 0.0 2.3 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase FYVE_2 PF02318.16 CRK40429.1 - 0.002 18.4 0.5 0.002 18.4 0.5 1.7 2 0 0 2 2 2 1 FYVE-type zinc finger ANTH PF07651.16 CRK40430.1 - 1.7e-32 112.5 1.3 2.3e-32 112.1 1.3 1.2 1 0 0 1 1 1 1 ANTH domain SesA PF17107.5 CRK40431.1 - 0.00078 19.6 0.6 0.0017 18.6 0.6 1.5 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF3361 PF11841.8 CRK40431.1 - 0.017 15.0 0.1 0.034 14.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3361) ING PF12998.7 CRK40431.1 - 0.3 11.7 1.2 0.65 10.6 1.2 1.6 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding ANTH PF07651.16 CRK40432.1 - 2.1e-70 236.9 2.3 2.8e-70 236.5 2.3 1.1 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 CRK40432.1 - 1.2e-07 31.8 0.0 1.9e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 ENTH domain MAT1 PF06391.13 CRK40433.1 - 1.2e-33 116.7 9.2 1.5e-33 116.4 9.2 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 CRK40433.1 - 5.4e-29 99.9 7.9 8.1e-29 99.3 7.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CRK40433.1 - 0.0077 16.1 2.8 0.02 14.8 2.8 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CRK40433.1 - 0.0094 15.8 4.2 0.021 14.6 4.2 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CRK40433.1 - 0.062 13.6 4.5 0.11 12.8 4.5 1.4 1 0 0 1 1 1 0 Ring finger domain Zn_ribbon_17 PF17120.5 CRK40433.1 - 0.095 12.3 1.1 0.19 11.3 1.1 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 CRK40433.1 - 0.21 11.6 8.5 2 8.4 8.7 2.1 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 CRK40433.1 - 0.57 10.3 4.5 1.1 9.3 4.5 1.4 1 0 0 1 1 1 0 RING-type zinc-finger MRP-S26 PF14943.6 CRK40433.1 - 0.74 9.7 13.8 1.2 9.1 13.8 1.2 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 zf-RING_6 PF14835.6 CRK40433.1 - 0.8 9.6 3.5 1.9 8.4 0.7 2.7 1 1 1 2 2 2 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 CRK40433.1 - 5.1 7.0 9.3 41 4.1 9.8 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain vATP-synt_E PF01991.18 CRK40433.1 - 6.5 6.1 14.9 10 5.5 14.9 1.3 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit CS PF04969.16 CRK40434.1 - 7.4e-15 55.7 0.0 1.4e-14 54.9 0.0 1.5 1 0 0 1 1 1 1 CS domain LIM_bind PF01803.16 CRK40434.1 - 0.035 13.6 1.7 0.053 13.0 1.7 1.2 1 0 0 1 1 1 0 LIM-domain binding protein Mpv17_PMP22 PF04117.12 CRK40435.1 - 1.2e-23 83.1 1.5 2.7e-23 82.0 1.5 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family CLTH PF10607.9 CRK40437.1 - 1.1e-29 103.2 0.0 2.7e-29 102.0 0.0 1.7 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 CRK40437.1 - 7.7e-09 35.4 2.8 1.4e-08 34.6 2.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CRK40437.1 - 7.7e-06 25.8 1.9 1.3e-05 25.0 1.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CRK40437.1 - 0.00012 21.9 2.0 0.0002 21.1 2.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CRK40437.1 - 0.00048 20.4 3.1 0.0008 19.7 3.1 1.4 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 CRK40437.1 - 0.00074 19.3 3.3 0.0014 18.4 3.3 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 CRK40437.1 - 0.0032 17.3 3.7 0.0055 16.5 3.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CRK40437.1 - 0.0033 17.3 3.3 0.0059 16.5 3.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CRK40437.1 - 0.0064 16.6 1.2 0.014 15.6 1.2 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Rtf2 PF04641.12 CRK40437.1 - 0.031 13.6 0.1 0.031 13.6 0.1 3.0 3 1 0 3 3 3 0 Rtf2 RING-finger zf-RING_4 PF14570.6 CRK40437.1 - 0.054 13.3 1.5 0.093 12.5 1.5 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Pet20 PF08692.10 CRK40437.1 - 0.12 13.0 0.0 0.33 11.7 0.0 1.7 1 0 0 1 1 1 0 Mitochondrial protein Pet20 PsbI PF02532.14 CRK40438.1 - 0.085 12.8 0.4 0.42 10.6 0.4 2.3 1 0 0 1 1 1 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) MFS_1 PF07690.16 CRK40439.1 - 9.9e-33 113.5 24.6 1.7e-27 96.3 9.7 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK40439.1 - 7.3e-14 51.5 0.1 7.3e-14 51.5 0.1 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter DUF819 PF05684.12 CRK40439.1 - 0.02 13.9 5.8 0.036 13.1 2.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF819) zf-Tim10_DDP PF02953.15 CRK40440.1 - 4e-17 61.6 2.9 4.7e-17 61.4 2.9 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF3556 PF12077.8 CRK40440.1 - 0.055 11.9 0.1 0.055 11.9 0.1 1.0 1 0 0 1 1 1 0 Transmembrane protein of unknown function (DUF3556) tRNA-synt_2 PF00152.20 CRK40442.1 - 5.6e-62 209.6 0.0 7.7e-62 209.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CRK40442.1 - 7.5e-07 29.0 0.0 1.5e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CRK40442.1 - 2.5e-05 23.9 0.0 0.0062 16.0 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti-like PF12869.7 CRK40442.1 - 0.24 11.0 0.0 0.43 10.2 0.0 1.3 1 0 0 1 1 1 0 tRNA_anti-like PH_6 PF15406.6 CRK40444.1 - 1.2e-46 157.6 1.8 1.2e-46 157.6 1.8 3.2 3 1 0 3 3 3 1 Pleckstrin homology domain PH PF00169.29 CRK40444.1 - 0.02 15.4 0.0 0.044 14.3 0.0 1.7 1 0 0 1 1 1 0 PH domain eRF1_3 PF03465.15 CRK40457.1 - 0.024 15.1 0.0 0.029 14.8 0.0 1.2 1 0 0 1 1 1 0 eRF1 domain 3 SMBP PF16785.5 CRK40457.1 - 0.029 14.6 0.0 0.036 14.3 0.0 1.1 1 0 0 1 1 1 0 Small metal-binding protein ANTH PF07651.16 CRK40466.1 - 0.00069 18.7 10.1 0.004 16.2 10.1 2.0 1 1 0 1 1 1 1 ANTH domain PIN_8 PF18476.1 CRK40466.1 - 0.95 9.3 10.8 1.1 9.1 10.8 1.1 1 0 0 1 1 1 0 PIN like domain TALPID3 PF15324.6 CRK40466.1 - 1.1 6.9 16.8 1 6.9 16.8 1.0 1 0 0 1 1 1 0 Hedgehog signalling target Glyco_hydro_56 PF01630.18 CRK40466.1 - 2 7.3 10.5 1.1 8.2 8.6 1.4 1 1 0 1 1 1 0 Hyaluronidase DUF3523 PF12037.8 CRK40466.1 - 2.7 7.3 29.3 5.2 6.4 29.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) TFIIA PF03153.13 CRK40466.1 - 7.3 6.5 21.4 7.9 6.4 21.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MDM10 PF12519.8 CRK40466.1 - 8.8 5.1 12.6 11 4.8 12.6 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 SNF2_N PF00176.23 CRK40468.1 - 8.1e-51 172.8 0.2 5e-38 130.7 0.0 2.1 2 0 0 2 2 2 2 SNF2 family N-terminal domain ResIII PF04851.15 CRK40468.1 - 3.6e-05 23.9 0.1 0.0017 18.4 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CRK40468.1 - 0.00028 20.7 0.0 0.00063 19.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ThiF PF00899.21 CRK40471.1 - 7.1e-64 215.5 0.0 5.3e-59 199.5 0.0 2.1 2 0 0 2 2 2 2 ThiF family E1_4HB PF16191.5 CRK40471.1 - 8.3e-25 86.8 1.3 2.6e-24 85.2 1.3 1.9 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 four-helix bundle UBA_e1_thiolCys PF10585.9 CRK40471.1 - 0.15 11.9 0.1 1.2 9.1 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-activating enzyme active site Chalcone_2 PF16035.5 CRK40473.1 - 7.3e-16 58.6 0.1 1.2e-15 57.9 0.1 1.3 1 0 0 1 1 1 1 Chalcone isomerase like DUF1534 PF07551.11 CRK40473.1 - 3.9 7.3 9.9 2.1 8.1 4.0 3.1 2 2 1 3 3 3 0 Protein of unknown function (DUF1534) RRM_1 PF00076.22 CRK40483.1 - 1.1e-14 54.0 0.0 4.2e-11 42.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CRK40483.1 - 0.014 15.2 0.0 0.021 14.6 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif FMN_dh PF01070.18 CRK40485.1 - 2.1e-38 132.2 2.9 2.4e-38 132.1 0.1 2.1 2 0 0 2 2 2 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 CRK40485.1 - 2.9e-18 65.8 0.0 5.7e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF3712 PF12505.8 CRK40485.1 - 2.3e-09 37.6 0.4 5.3e-09 36.4 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) adh_short PF00106.25 CRK40486.1 - 1.8e-20 73.2 0.0 2.4e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK40486.1 - 4e-12 46.2 0.2 6e-12 45.6 0.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK40486.1 - 3.1e-06 27.2 0.5 4.7e-06 26.6 0.2 1.5 2 1 0 2 2 2 1 KR domain DUF2057 PF09829.9 CRK40486.1 - 0.14 12.3 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) CoA_transf_3 PF02515.17 CRK40488.1 - 8.7e-33 113.9 0.1 1.1e-32 113.6 0.1 1.1 1 0 0 1 1 1 1 CoA-transferase family III Asp PF00026.23 CRK40499.1 - 6.2e-90 301.8 0.8 1.5e-71 241.4 1.3 2.1 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 CRK40499.1 - 1.2e-16 61.5 1.1 2.5e-08 34.4 0.6 2.6 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 CRK40499.1 - 0.0042 17.6 0.0 0.015 15.9 0.0 2.0 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CRK40499.1 - 0.0059 17.2 0.0 0.023 15.3 0.0 2.0 1 1 0 1 1 1 1 Aspartyl protease TFIIA PF03153.13 CRK40499.1 - 1.1 9.2 21.7 1.4 8.9 21.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Homeodomain PF00046.29 CRK40501.1 - 8.5e-21 73.6 2.2 2e-20 72.4 2.2 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CRK40501.1 - 0.0014 18.5 0.4 0.0014 18.5 0.4 1.6 2 0 0 2 2 2 1 Homeobox KN domain Tho2 PF11262.8 CRK40501.1 - 0.17 11.1 1.1 0.2 10.9 1.1 1.1 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF4551 PF15087.6 CRK40501.1 - 0.49 9.2 3.6 0.54 9.0 3.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Ndc1_Nup PF09531.10 CRK40501.1 - 1.7 7.3 5.9 1.8 7.1 5.9 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup EphA2_TM PF14575.6 CRK40503.1 - 0.028 15.3 0.0 0.028 15.3 0.0 2.4 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain ECSCR PF15820.5 CRK40503.1 - 0.073 12.9 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Neur_chan_memb PF02932.16 CRK40503.1 - 0.12 12.4 5.8 0.26 11.3 5.8 1.4 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region LRR19-TM PF15176.6 CRK40503.1 - 0.14 12.2 0.1 0.33 11.0 0.1 1.8 1 1 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Phage_holin_2_4 PF16082.5 CRK40503.1 - 0.17 11.7 0.1 0.17 11.7 0.1 1.9 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like WBP-1 PF11669.8 CRK40503.1 - 0.31 11.7 0.0 0.31 11.7 0.0 2.2 2 1 0 2 2 2 0 WW domain-binding protein 1 FAM176 PF14851.6 CRK40503.1 - 0.56 9.9 3.5 24 4.6 0.0 2.1 2 0 0 2 2 2 0 FAM176 family SCIMP PF15050.6 CRK40503.1 - 0.73 10.3 3.8 0.39 11.2 0.1 2.4 1 1 2 3 3 3 0 SCIMP protein TFIIA PF03153.13 CRK40503.1 - 2.2 8.2 15.1 2.7 7.9 15.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Rhomboid_SP PF12595.8 CRK40504.1 - 0.076 12.4 2.1 0.11 11.8 2.1 1.3 1 0 0 1 1 1 0 Rhomboid serine protease SCRL PF06876.12 CRK40505.1 - 0.49 10.6 4.4 0.81 9.9 4.4 1.3 1 0 0 1 1 1 0 Plant self-incompatibility response (SCRL) protein MBR1 PF17058.5 CRK40505.1 - 0.5 10.6 9.4 1.3 9.3 4.1 2.0 1 1 1 2 2 2 0 Mitochondrial biogenesis regulation protein 1 Apc13p PF05839.11 CRK40506.1 - 1.2e-31 108.7 0.2 1.3e-31 108.6 0.2 1.0 1 0 0 1 1 1 1 Apc13p protein CRAL_TRIO PF00650.20 CRK40507.1 - 1.2e-81 272.1 0.0 1.2e-39 135.6 0.0 2.2 2 0 0 2 2 2 2 CRAL/TRIO domain TRAPP PF04051.16 CRK40507.1 - 2e-77 257.9 0.0 3.1e-40 137.2 0.0 2.2 2 0 0 2 2 2 2 Transport protein particle (TRAPP) component CRAL_TRIO_N PF03765.15 CRK40507.1 - 5.6e-28 96.9 0.7 6.8e-13 48.6 0.0 2.9 2 0 0 2 2 2 2 CRAL/TRIO, N-terminal domain HTH_8 PF02954.19 CRK40507.1 - 2.4e-06 27.2 1.5 0.026 14.3 0.1 2.6 2 0 0 2 2 2 2 Bacterial regulatory protein, Fis family CRAL_TRIO_2 PF13716.6 CRK40507.1 - 0.00029 21.0 0.0 0.95 9.6 0.0 2.3 2 0 0 2 2 2 2 Divergent CRAL/TRIO domain Cactin_mid PF10312.9 CRK40507.1 - 0.0007 19.4 0.1 1.3 8.7 0.0 2.2 2 0 0 2 2 2 2 Conserved mid region of cactin HNH_5 PF14279.6 CRK40507.1 - 0.2 11.5 0.0 32 4.5 0.0 2.4 2 0 0 2 2 2 0 HNH endonuclease GalKase_gal_bdg PF10509.9 CRK40507.1 - 1.8 8.2 3.3 38 3.9 0.2 2.7 2 0 0 2 2 2 0 Galactokinase galactose-binding signature Apc13p PF05839.11 CRK40509.1 - 1.2e-31 108.7 0.2 1.3e-31 108.6 0.2 1.0 1 0 0 1 1 1 1 Apc13p protein Fungal_trans PF04082.18 CRK40515.1 - 1.4e-21 76.7 0.1 2.6e-21 75.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK40515.1 - 4.5e-09 36.3 8.6 7.1e-09 35.7 8.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IPPT PF01715.17 CRK40516.1 - 5.5e-57 193.2 0.0 1e-56 192.3 0.0 1.4 1 0 0 1 1 1 1 IPP transferase zf-met PF12874.7 CRK40516.1 - 7.5e-08 32.5 2.8 1.6e-07 31.5 2.8 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CRK40516.1 - 5.1e-06 26.6 2.7 5.1e-06 26.6 2.7 1.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding IPT PF01745.16 CRK40516.1 - 0.00027 20.4 0.0 0.0014 18.1 0.0 1.9 2 0 0 2 2 2 1 Isopentenyl transferase zf-C2H2_2 PF12756.7 CRK40516.1 - 0.00034 20.9 0.9 0.00062 20.1 0.9 1.3 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) AAA_33 PF13671.6 CRK40516.1 - 0.0021 18.3 0.4 0.045 13.9 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 CRK40516.1 - 0.012 16.0 0.0 0.039 14.3 0.0 2.0 2 1 0 2 2 2 0 AAA ATPase domain KTI12 PF08433.10 CRK40516.1 - 0.061 12.8 0.1 1.6 8.2 0.0 2.2 2 0 0 2 2 2 0 Chromatin associated protein KTI12 NACHT PF05729.12 CRK40516.1 - 0.07 13.0 0.0 0.41 10.5 0.0 2.1 2 0 0 2 2 2 0 NACHT domain Hpr_kinase_C PF07475.12 CRK40516.1 - 0.076 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain zf-C2H2_6 PF13912.6 CRK40516.1 - 0.6 10.2 2.4 0.93 9.6 2.4 1.3 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 CRK40516.1 - 3.7 8.2 4.5 6.9 7.3 4.5 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type Plug_translocon PF10559.9 CRK40519.1 - 2e-17 62.7 0.3 4e-17 61.7 0.3 1.5 1 0 0 1 1 1 1 Plug domain of Sec61p SecY PF00344.20 CRK40519.1 - 2.6e-16 59.8 1.5 4.4e-16 59.0 1.5 1.3 1 0 0 1 1 1 1 SecY translocase ABC_membrane PF00664.23 CRK40520.1 - 4.9e-93 311.7 35.7 6.5e-36 124.4 5.6 4.4 4 0 0 4 4 4 4 ABC transporter transmembrane region ABC_tran PF00005.27 CRK40520.1 - 2.5e-52 177.0 0.0 5.9e-31 107.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CRK40520.1 - 2.2e-08 33.8 1.5 0.0017 17.9 0.2 3.9 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CRK40520.1 - 1.9e-07 31.8 0.2 0.0026 18.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 CRK40520.1 - 0.0001 22.3 0.1 3.5 7.3 0.0 3.4 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 CRK40520.1 - 0.00015 22.2 0.2 0.19 12.1 0.0 3.2 3 0 0 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 CRK40520.1 - 0.0003 20.5 0.5 0.9 9.3 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 CRK40520.1 - 0.00041 20.4 0.0 0.1 12.7 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CRK40520.1 - 0.00074 19.5 0.0 1.4 8.8 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase T2SSE PF00437.20 CRK40520.1 - 0.00083 18.5 0.0 0.054 12.6 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein ResB PF05140.14 CRK40520.1 - 0.0018 17.1 0.8 0.74 8.5 0.1 2.3 2 0 0 2 2 2 2 ResB-like family IstB_IS21 PF01695.17 CRK40520.1 - 0.0024 17.6 0.1 0.17 11.6 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein Taeniidae_ag PF05596.11 CRK40520.1 - 0.0051 16.8 0.5 5.3 7.1 0.1 2.7 2 0 0 2 2 2 2 Taeniidae antigen DUF87 PF01935.17 CRK40520.1 - 0.0064 16.6 2.6 0.041 14.0 0.0 2.8 3 0 0 3 3 3 1 Helicase HerA, central domain ResIII PF04851.15 CRK40520.1 - 0.014 15.4 0.1 9.7 6.2 0.0 2.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CRK40520.1 - 0.017 15.4 0.0 18 5.6 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.6 CRK40520.1 - 0.02 14.4 0.2 0.74 9.3 0.1 2.4 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 CRK40520.1 - 0.026 14.3 0.1 11 5.8 0.0 3.8 3 1 0 3 3 3 0 DEAD/DEAH box helicase AAA PF00004.29 CRK40520.1 - 0.047 14.1 0.1 16 5.9 0.0 3.4 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 CRK40520.1 - 0.053 12.8 0.2 12 5.1 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin S-AdoMet_synt_C PF02773.16 CRK40520.1 - 0.07 13.1 0.1 16 5.5 0.0 3.3 3 1 0 3 3 3 0 S-adenosylmethionine synthetase, C-terminal domain TrwB_AAD_bind PF10412.9 CRK40520.1 - 0.083 11.8 1.0 7.5 5.3 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.6 CRK40520.1 - 0.11 12.2 0.8 11 5.7 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA_24 PF13479.6 CRK40520.1 - 0.12 12.0 0.2 10 5.8 0.0 3.1 3 0 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.18 CRK40520.1 - 0.16 11.3 0.2 1.2 8.4 0.1 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_7 PF12775.7 CRK40520.1 - 0.16 11.4 0.1 19 4.7 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_15 PF13175.6 CRK40520.1 - 0.17 11.6 0.0 5 6.7 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain Dynamin_N PF00350.23 CRK40520.1 - 0.23 11.5 0.4 11 6.0 0.0 2.6 2 0 0 2 2 2 0 Dynamin family PTP_tm PF18861.1 CRK40520.1 - 0.76 9.7 5.6 13 5.7 0.5 2.5 2 0 0 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J DUF4337 PF14235.6 CRK40520.1 - 3.7 7.6 7.0 0.68 10.0 2.0 2.4 2 0 0 2 2 1 0 Domain of unknown function (DUF4337) ADH_N PF08240.12 CRK40522.1 - 6e-30 103.3 0.5 1.2e-29 102.4 0.5 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CRK40522.1 - 8.3e-11 42.0 0.0 1.3e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 CRK40522.1 - 1.9e-05 24.3 0.5 0.12 11.8 0.3 2.7 2 1 0 2 2 2 2 Glucose dehydrogenase C-terminus Pyr_redox_3 PF13738.6 CRK40522.1 - 0.26 10.5 0.5 3.4 6.8 0.7 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Zn_clus PF00172.18 CRK40523.1 - 1.5e-08 34.6 10.2 2.4e-08 33.9 10.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 CRK40524.1 - 2.9e-17 62.6 1.9 5.7e-17 61.6 1.9 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain SIP PF04954.13 CRK40524.1 - 0.021 15.3 0.0 0.05 14.1 0.0 1.7 1 0 0 1 1 1 0 Siderophore-interacting protein Abhydrolase_1 PF00561.20 CRK40525.1 - 1.3e-09 38.1 0.2 1.9e-09 37.6 0.2 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 CRK40525.1 - 1.6e-09 37.8 0.0 3.4e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein DUF3873 PF12989.7 CRK40525.1 - 0.18 12.2 0.0 21 5.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF3873) Glyco_trans_2_3 PF13632.6 CRK40526.1 - 5.7e-47 160.2 2.5 5.7e-47 160.2 2.5 2.1 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 CRK40526.1 - 5.3e-05 23.1 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 CRK40526.1 - 0.00078 19.4 0.0 0.0013 18.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 CRK40526.1 - 0.0016 18.0 0.0 0.0032 17.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 HhH-GPD PF00730.25 CRK40527.1 - 3.1e-08 34.0 0.0 9.1e-08 32.5 0.0 1.9 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein PUF PF00806.19 CRK40527.1 - 0.044 13.5 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Pumilio-family RNA binding repeat HHH PF00633.23 CRK40527.1 - 0.071 13.0 0.0 0.19 11.6 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif FAD_binding_4 PF01565.23 CRK40528.1 - 5.9e-24 84.4 0.6 1.3e-23 83.3 0.6 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 CRK40528.1 - 0.00096 19.2 0.7 0.0031 17.6 0.1 2.0 2 0 0 2 2 2 1 Berberine and berberine like DUF4286 PF14114.6 CRK40529.1 - 0.0049 17.3 0.0 0.77 10.3 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4286) EthD PF07110.11 CRK40529.1 - 0.027 15.6 0.1 0.34 12.1 0.0 2.2 2 0 0 2 2 2 0 EthD domain Lipocalin_2 PF08212.12 CRK40530.1 - 3.7e-20 72.4 0.0 4.3e-20 72.1 0.0 1.1 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.23 CRK40530.1 - 0.0002 21.6 0.0 0.0006 20.0 0.0 1.7 1 1 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Hva1_TUDOR PF11160.8 CRK40531.1 - 6.5e-16 58.3 2.2 6.5e-16 58.3 2.2 2.1 2 0 0 2 2 2 1 Hypervirulence associated proteins TUDOR domain DUF3140 PF11338.8 CRK40531.1 - 4.4e-09 36.6 0.2 4.4e-09 36.6 0.2 3.4 2 1 0 2 2 2 1 Protein of unknown function (DUF3140) CDC27 PF09507.10 CRK40531.1 - 0.21 10.9 35.2 0.3 10.5 35.2 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Cupin_1 PF00190.22 CRK40532.1 - 2.2e-39 134.5 0.0 4.6e-19 68.5 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 CRK40532.1 - 1.4e-26 92.0 1.2 1.5e-12 47.0 0.2 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 CRK40532.1 - 3.4e-10 39.5 0.0 0.00037 20.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 CRK40532.1 - 1.2e-07 31.7 0.2 0.0013 18.6 0.1 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain ARD PF03079.14 CRK40532.1 - 0.00088 19.5 0.2 0.36 11.0 0.0 2.3 2 0 0 2 2 2 2 ARD/ARD' family MannoseP_isomer PF01050.18 CRK40532.1 - 0.051 13.5 0.0 0.19 11.6 0.0 1.8 2 0 0 2 2 2 0 Mannose-6-phosphate isomerase Cupin_7 PF12973.7 CRK40532.1 - 0.078 12.9 0.6 0.49 10.4 0.2 2.4 2 1 0 2 2 2 0 ChrR Cupin-like domain CENP-C_C PF11699.8 CRK40532.1 - 0.14 12.4 0.0 5.3 7.3 0.0 2.3 2 0 0 2 2 2 0 Mif2/CENP-C like DUF1275 PF06912.11 CRK40533.1 - 8.2e-46 156.4 13.0 1.2e-45 155.8 13.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF2142 PF09913.9 CRK40533.1 - 0.01 14.7 3.3 0.011 14.6 1.2 1.9 1 1 0 2 2 2 0 Predicted membrane protein (DUF2142) Peptidase_M14 PF00246.24 CRK40534.1 - 7.1e-13 49.0 0.0 1.2e-12 48.2 0.0 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 CRK40534.1 - 0.00032 19.9 0.4 0.00072 18.7 0.1 1.7 2 0 0 2 2 2 1 Succinylglutamate desuccinylase / Aspartoacylase family DUF2817 PF10994.8 CRK40534.1 - 0.072 12.5 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2817) Abhydrolase_6 PF12697.7 CRK40536.1 - 6.2e-13 49.9 2.2 8.4e-13 49.4 2.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3140 PF11338.8 CRK40537.1 - 1.1e-26 93.1 3.6 1.1e-26 93.1 3.6 4.0 3 2 0 3 3 3 1 Protein of unknown function (DUF3140) Hva1_TUDOR PF11160.8 CRK40537.1 - 2.7e-15 56.2 2.5 2.7e-15 56.2 2.5 2.5 2 0 0 2 2 2 1 Hypervirulence associated proteins TUDOR domain DUF1275 PF06912.11 CRK40538.1 - 5.4e-46 157.0 11.3 6.6e-46 156.7 11.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF2142 PF09913.9 CRK40538.1 - 0.0024 16.8 0.5 0.0024 16.8 0.5 1.7 2 0 0 2 2 2 1 Predicted membrane protein (DUF2142) Peptidase_M14 PF00246.24 CRK40539.1 - 3.9e-13 49.9 0.1 8.2e-13 48.8 0.1 1.5 2 0 0 2 2 2 1 Zinc carboxypeptidase AstE_AspA PF04952.14 CRK40539.1 - 0.0003 19.9 0.4 0.00079 18.6 0.1 1.8 2 0 0 2 2 2 1 Succinylglutamate desuccinylase / Aspartoacylase family DUF2817 PF10994.8 CRK40539.1 - 0.071 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2817) Isochorismatase PF00857.20 CRK40540.1 - 2e-45 155.1 0.1 2.2e-45 154.9 0.1 1.0 1 0 0 1 1 1 1 Isochorismatase family Glyco_hydro_3_C PF01915.22 CRK40540.1 - 0.12 12.3 0.0 0.56 10.1 0.0 1.9 1 1 1 2 2 2 0 Glycosyl hydrolase family 3 C-terminal domain Isochorismatase PF00857.20 CRK40544.1 - 2.2e-43 148.5 0.1 2.5e-43 148.3 0.1 1.0 1 0 0 1 1 1 1 Isochorismatase family Imm5 PF14423.6 CRK40544.1 - 0.096 12.9 0.0 3.6 7.8 0.0 2.0 2 0 0 2 2 2 0 Immunity protein Imm5 CAF1A PF12253.8 CRK40547.1 - 8.1e-21 74.0 0.5 8.1e-21 74.0 0.5 4.1 3 1 0 3 3 3 2 Chromatin assembly factor 1 subunit A HTH_16 PF12645.7 CRK40547.1 - 0.43 10.7 3.9 2 8.5 0.2 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain SPX PF03105.19 CRK40551.1 - 1.1e-81 275.7 0.2 1.5e-81 275.3 0.2 1.2 1 0 0 1 1 1 1 SPX domain EXS PF03124.14 CRK40551.1 - 3.9e-70 236.8 17.0 5.4e-70 236.3 17.0 1.1 1 0 0 1 1 1 1 EXS family NEMP PF10225.9 CRK40551.1 - 2.1 8.0 5.1 1.6 8.4 2.4 2.0 1 1 1 2 2 2 0 NEMP family EXS PF03124.14 CRK40556.1 - 7.4e-100 334.5 25.8 9.2e-100 334.2 25.8 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.19 CRK40556.1 - 7.6e-65 220.3 19.3 3.7e-36 125.9 2.9 2.5 2 1 1 3 3 3 2 SPX domain Peptidase_M18 PF02127.15 CRK40558.1 - 1.4e-186 620.5 0.0 1.2e-123 413.1 0.0 2.0 2 0 0 2 2 2 2 Aminopeptidase I zinc metalloprotease (M18) 2OG-FeII_Oxy PF03171.20 CRK40559.1 - 1.6e-12 47.8 0.0 3.2e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 CRK40559.1 - 2.7e-09 37.8 0.0 4.2e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Rsm22 PF09243.10 CRK40559.1 - 0.081 12.2 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 Sugar_tr PF00083.24 CRK40561.1 - 1.8e-35 122.7 10.0 2.4e-35 122.3 10.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter DIOX_N PF14226.6 CRK40561.1 - 4.2e-09 37.2 0.0 6.8e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 CRK40561.1 - 3.9e-06 27.3 0.0 7.7e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 CRK40561.1 - 1.4e-05 24.2 10.1 2.1e-05 23.6 10.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Rsm22 PF09243.10 CRK40561.1 - 0.12 11.6 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 CCDC53 PF10152.9 CRK40562.1 - 3.5 8.0 8.4 0.73 10.2 1.6 2.5 2 1 0 2 2 2 0 Subunit CCDC53 of WASH complex Sugar_tr PF00083.24 CRK40563.1 - 2.5e-150 501.3 18.5 6.1e-85 285.8 10.4 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CRK40563.1 - 5e-25 88.2 53.2 9e-13 47.9 15.3 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.6 CRK40563.1 - 5.4e-05 21.9 29.3 0.0024 16.5 0.7 4.3 3 2 1 4 4 4 3 MFS/sugar transport protein RsmJ PF04378.13 CRK40563.1 - 0.087 12.0 0.1 8.7 5.5 0.0 2.2 2 0 0 2 2 2 0 Ribosomal RNA large subunit methyltransferase D, RlmJ DUF2530 PF10745.9 CRK40563.1 - 7.3 6.9 6.8 38 4.6 0.1 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF2530) Methyltransf_11 PF08241.12 CRK40564.1 - 1e-15 58.1 0.0 2e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK40564.1 - 3.2e-14 53.4 0.0 6.6e-14 52.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK40564.1 - 9.5e-10 39.1 0.0 1.7e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK40564.1 - 3.4e-07 30.2 0.0 5.4e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CRK40564.1 - 5.7e-05 23.0 0.0 0.0002 21.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 CRK40564.1 - 0.2 11.2 0.0 0.81 9.2 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase small domain Peptidase_M14 PF00246.24 CRK40565.1 - 8.6e-55 186.6 0.0 1.1e-54 186.2 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase ADH_zinc_N PF00107.26 CRK40566.1 - 4.8e-21 75.1 1.1 6.9e-21 74.6 0.2 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CRK40566.1 - 2.2e-11 44.9 0.0 5.9e-11 43.5 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CRK40566.1 - 0.0011 18.8 0.5 0.0025 17.7 0.5 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 CRK40566.1 - 0.053 13.8 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain RRM_1 PF00076.22 CRK40574.1 - 7.6e-09 35.3 0.1 1.4e-08 34.4 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nefa_Nip30_N PF10187.9 CRK40574.1 - 0.0022 18.4 0.4 0.0036 17.6 0.4 1.3 1 0 0 1 1 1 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 HypA PF01155.19 CRK40592.1 - 0.072 13.1 0.0 0.089 12.8 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA GTP_cyclohydroI PF01227.22 CRK40594.1 - 2.8e-63 212.6 1.7 1.4e-58 197.3 1.3 2.1 1 1 1 2 2 2 2 GTP cyclohydrolase I QueF PF14489.6 CRK40594.1 - 0.0053 16.9 0.0 0.014 15.6 0.0 1.7 2 0 0 2 2 2 1 QueF-like protein HNH_2 PF13391.6 CRK40596.1 - 2.3e-11 43.6 0.1 4.7e-11 42.7 0.1 1.5 1 0 0 1 1 1 1 HNH endonuclease LYRIC PF15686.5 CRK40631.1 - 0.011 15.3 0.0 0.012 15.2 0.0 1.0 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family DUF5527 PF17665.1 CRK40631.1 - 0.022 14.3 0.1 0.024 14.2 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5527) TMIE PF16038.5 CRK40631.1 - 0.049 13.5 0.1 0.069 13.0 0.1 1.3 1 0 0 1 1 1 0 TMIE protein DUF4223 PF13978.6 CRK40631.1 - 0.06 13.3 0.0 0.08 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4223) DUF1772 PF08592.11 CRK40631.1 - 0.076 13.3 0.0 0.088 13.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) ArsA_ATPase PF02374.15 CRK40633.1 - 2.1e-25 89.5 0.7 2.3e-25 89.4 0.7 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase M20_dimer PF07687.14 CRK40634.1 - 2.6e-07 30.5 0.0 3.4e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase dimerisation domain AnfO_nitrog PF09582.10 CRK40634.1 - 0.035 13.5 0.6 0.05 12.9 0.6 1.2 1 0 0 1 1 1 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) MCM_N PF14551.6 CRK40651.1 - 6e-15 55.7 0.0 3.1e-14 53.4 0.0 1.9 2 0 0 2 2 2 1 MCM N-terminal domain MCM_OB PF17207.3 CRK40651.1 - 2e-12 47.1 0.1 3.5e-12 46.3 0.1 1.3 1 0 0 1 1 1 1 MCM OB domain tRNA-synt_2d PF01409.20 CRK40670.1 - 3.6e-27 95.4 0.0 5.5e-27 94.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) CPSase_L_D2 PF02786.17 CRK40670.1 - 9.3e-09 35.1 0.0 1.3e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_Ter PF15632.6 CRK40670.1 - 3.6e-06 26.8 0.0 1.1e-05 25.2 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.22 CRK40670.1 - 0.00027 20.5 0.0 0.00062 19.4 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 CRK40670.1 - 0.067 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus MGS PF02142.22 CRK40670.1 - 0.16 12.2 0.0 0.47 10.7 0.0 1.8 1 0 0 1 1 1 0 MGS-like domain zf-C2H2 PF00096.26 CRK40671.1 - 0.012 16.0 0.1 0.02 15.3 0.1 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type CCDC106 PF15794.5 CRK40671.1 - 0.76 9.4 4.4 0.76 9.4 4.4 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Tudor-knot PF11717.8 CRK40674.1 - 3.5e-10 39.6 1.5 4.6e-10 39.2 1.5 1.2 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Iso_dh PF00180.20 CRK40675.1 - 1.9e-76 257.5 0.0 2.3e-76 257.2 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Thioredoxin_7 PF13899.6 CRK40675.1 - 8.6e-11 41.9 0.1 2.1e-10 40.7 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin-like XRN_M PF17846.1 CRK40680.1 - 2.8e-38 132.0 0.0 3.7e-38 131.6 0.0 1.1 1 0 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 CRK40680.1 - 4.2e-38 131.2 0.4 8e-38 130.2 0.0 1.6 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus zf-CCHC_2 PF13696.6 CRK40680.1 - 0.039 13.8 3.3 0.084 12.7 3.3 1.5 1 0 0 1 1 1 0 Zinc knuckle DENN PF02141.21 CRK40686.1 - 1.9e-56 191.0 0.0 3e-56 190.3 0.0 1.3 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.19 CRK40686.1 - 1.4e-15 57.0 0.6 6.1e-15 55.0 0.7 2.0 2 0 0 2 2 2 1 dDENN domain uDENN PF03456.18 CRK40686.1 - 8.8e-14 52.0 0.0 2.1e-13 50.8 0.0 1.7 1 0 0 1 1 1 1 uDENN domain C1_2 PF03107.16 CRK40686.1 - 0.049 14.0 5.4 0.092 13.1 5.4 1.4 1 0 0 1 1 1 0 C1 domain SPA PF08616.10 CRK40686.1 - 0.16 12.0 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Stabilization of polarity axis C1_1 PF00130.22 CRK40686.1 - 0.44 10.5 8.9 0.97 9.4 8.9 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.29 CRK40686.1 - 2.3 8.2 8.6 4.9 7.1 8.6 1.5 1 0 0 1 1 1 0 PHD-finger SNAP PF14938.6 CRK40687.1 - 7.4e-91 304.5 14.3 9.2e-91 304.2 14.3 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 CRK40687.1 - 0.0001 22.5 13.6 0.078 13.3 1.4 3.3 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 CRK40687.1 - 0.0002 21.3 7.5 0.15 12.4 0.3 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 CRK40687.1 - 0.00025 20.9 3.3 0.022 14.7 0.3 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 CRK40687.1 - 0.00088 19.2 12.2 2.4 8.5 0.2 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 CRK40687.1 - 0.0017 18.9 13.6 3.7 8.4 0.5 5.3 4 1 1 5 5 5 2 Tetratricopeptide repeat DUF2521 PF10730.9 CRK40687.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2521) TPR_1 PF00515.28 CRK40687.1 - 0.11 12.3 9.3 1.8 8.6 0.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 CRK40687.1 - 0.21 12.5 14.9 7.8 7.6 0.4 4.8 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 CRK40687.1 - 0.96 9.4 4.8 18 5.4 0.3 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 CRK40687.1 - 1.9 9.2 19.3 7.3 7.3 0.1 4.4 3 1 1 4 4 4 0 Tetratricopeptide repeat zf-CCCH PF00642.24 CRK40690.1 - 4.8e-08 32.7 3.7 9.7e-08 31.7 3.7 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 CRK40690.1 - 9e-08 31.9 5.0 1.5e-07 31.2 5.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CRK40690.1 - 3.6e-07 30.0 8.5 6.5e-07 29.1 8.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CRK40690.1 - 5.8e-07 29.4 6.8 1.1e-06 28.5 6.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CRK40690.1 - 6.9e-07 29.1 7.5 1.2e-06 28.4 7.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CRK40690.1 - 1.6e-06 27.8 7.9 2.7e-06 27.1 7.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf_CCCH_4 PF18345.1 CRK40690.1 - 1.9e-05 24.5 6.2 3.7e-05 23.6 6.2 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-RING_2 PF13639.6 CRK40690.1 - 2.6e-05 24.5 6.9 4.6e-05 23.7 6.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_10 PF16685.5 CRK40690.1 - 0.00015 21.8 3.3 0.00015 21.8 3.3 1.7 2 0 0 2 2 1 1 zinc RING finger of MSL2 zf-CCCH_4 PF18044.1 CRK40690.1 - 0.00021 21.0 3.1 0.00042 20.1 3.1 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger Prok-RING_4 PF14447.6 CRK40690.1 - 0.012 15.5 5.5 0.022 14.6 5.5 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 CRK40690.1 - 0.017 15.3 8.2 0.036 14.2 8.2 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-CCCH_2 PF14608.6 CRK40690.1 - 0.092 13.2 3.6 0.18 12.3 3.6 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Harakiri PF15196.6 CRK40690.1 - 0.1 13.1 1.1 0.24 11.9 1.1 1.6 1 0 0 1 1 1 0 Activator of apoptosis harakiri zf-rbx1 PF12678.7 CRK40690.1 - 0.32 11.3 3.2 0.71 10.2 3.2 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain Mcp5_PH PF12814.7 CRK40692.1 - 8.4e-45 151.8 0.1 1.7e-44 150.9 0.1 1.5 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 CRK40692.1 - 0.00018 22.0 0.0 0.00042 20.8 0.0 1.6 1 0 0 1 1 1 1 PH domain RasGAP_C PF03836.15 CRK40692.1 - 0.033 14.3 10.2 0.077 13.1 10.2 1.6 1 0 0 1 1 1 0 RasGAP C-terminus DNA_pol_B PF00136.21 CRK40693.1 - 5.4e-70 236.4 0.0 7.7e-70 235.9 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B zf-C4pol PF14260.6 CRK40693.1 - 8.1e-17 61.5 3.1 8.1e-17 61.5 3.1 2.1 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_exo1 PF03104.19 CRK40693.1 - 1.5e-06 27.6 0.0 2.6e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DZR PF12773.7 CRK40693.1 - 0.32 11.0 1.6 0.73 9.9 1.6 1.6 1 0 0 1 1 1 0 Double zinc ribbon S4 PF01479.25 CRK40694.1 - 3.2e-12 46.0 0.9 3.2e-12 46.0 0.9 2.5 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 CRK40694.1 - 7.4e-06 26.8 0.1 1.3e-05 26.0 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Uds1 PF15456.6 CRK40694.1 - 0.094 12.9 0.7 2.2 8.5 0.0 2.2 2 0 0 2 2 2 0 Up-regulated During Septation ANTH PF07651.16 CRK40696.1 - 3.7e-81 272.2 0.0 3.7e-81 272.2 0.0 2.6 2 1 0 2 2 2 1 ANTH domain I_LWEQ PF01608.17 CRK40696.1 - 1.1e-53 181.6 10.8 1.1e-53 181.6 10.8 6.1 4 1 1 6 6 6 2 I/LWEQ domain MATalpha_HMGbox PF04769.12 CRK40698.1 - 1.5e-47 161.5 0.0 2.1e-47 161.0 0.0 1.2 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG-box HMG_box PF00505.19 CRK40699.1 - 1.1e-19 70.6 1.7 1.7e-19 70.0 1.7 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CRK40699.1 - 0.00035 21.1 0.4 0.00059 20.4 0.4 1.3 1 0 0 1 1 1 1 HMG-box domain COX6A PF02046.15 CRK40701.1 - 3.2e-52 175.7 1.7 3.9e-52 175.4 1.7 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa ANAPC5 PF12862.7 CRK40702.1 - 3.9e-31 107.0 4.8 2.7e-30 104.3 3.5 2.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_7 PF13176.6 CRK40702.1 - 0.0003 20.6 0.4 0.12 12.4 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 CRK40702.1 - 0.0061 17.3 9.4 9.9 7.3 0.0 6.2 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 CRK40702.1 - 0.0083 15.9 1.9 8.5 6.4 0.0 3.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 CRK40702.1 - 0.0088 16.5 12.3 3.1 8.4 1.6 4.9 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_20 PF14561.6 CRK40702.1 - 0.016 15.5 1.7 10 6.5 0.2 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 CRK40702.1 - 0.017 15.2 0.2 4.3 7.7 0.1 3.8 2 0 0 2 2 2 0 Tetratricopeptide repeat FAT PF02259.23 CRK40702.1 - 0.03 13.5 0.1 0.66 9.1 0.0 2.4 2 0 0 2 2 2 0 FAT domain TPR_21 PF09976.9 CRK40702.1 - 0.14 11.8 3.1 0.63 9.7 0.1 3.3 4 1 0 4 4 4 0 Tetratricopeptide repeat-like domain CIA30 PF08547.12 CRK40703.1 - 4.1e-46 156.9 0.0 5.3e-46 156.5 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Exo_endo_phos PF03372.23 CRK40704.1 - 4e-10 39.6 0.1 6e-10 39.0 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family COX6A PF02046.15 CRK40705.1 - 1.7e-43 147.6 4.6 1.8e-42 144.3 0.3 2.0 2 0 0 2 2 2 2 Cytochrome c oxidase subunit VIa TPR_19 PF14559.6 CRK40706.1 - 0.00051 20.5 9.0 2.1 8.9 1.6 4.4 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 CRK40706.1 - 0.00064 19.6 0.1 0.087 12.9 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 CRK40706.1 - 0.0015 19.2 7.4 7 7.8 0.0 5.5 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 CRK40706.1 - 0.0061 16.3 1.4 6.1 6.8 0.0 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 CRK40706.1 - 0.013 15.5 0.8 3.1 8.1 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_21 PF09976.9 CRK40706.1 - 0.031 14.0 1.2 0.45 10.2 0.1 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat-like domain FAT PF02259.23 CRK40706.1 - 0.039 13.2 0.2 0.43 9.8 0.0 2.3 2 0 0 2 2 2 0 FAT domain TPR_20 PF14561.6 CRK40706.1 - 0.075 13.4 0.8 7.4 7.0 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 CRK40706.1 - 3.8 8.3 9.3 13 6.6 0.2 4.4 3 1 2 5 5 5 0 Tetratricopeptide repeat CIA30 PF08547.12 CRK40707.1 - 4.5e-45 153.5 0.0 7.5e-45 152.8 0.0 1.4 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) RRM_1 PF00076.22 CRK40707.1 - 1.6e-21 75.8 0.1 3.3e-11 42.9 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CRK40707.1 - 0.00041 20.4 0.0 0.64 10.2 0.0 3.2 4 0 0 4 4 4 2 RNA recognition motif Dioxygenase_C PF00775.21 CRK40709.1 - 2.2e-40 138.0 0.0 4.9e-40 136.9 0.0 1.6 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 CRK40709.1 - 1.5e-29 101.7 0.0 2.8e-29 100.8 0.0 1.5 1 0 0 1 1 1 1 Catechol dioxygenase N terminus SUI1 PF01253.22 CRK40709.1 - 9.2e-27 93.4 4.0 1.7e-26 92.5 4.0 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 CarboxypepD_reg PF13620.6 CRK40709.1 - 0.0002 21.5 0.0 0.00093 19.4 0.0 2.2 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain Big_1 PF02369.16 CRK40709.1 - 0.073 13.1 0.0 0.26 11.3 0.0 2.0 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 1) SSF PF00474.17 CRK40711.1 - 0.0011 17.9 29.0 0.011 14.7 29.0 2.0 1 1 0 1 1 1 1 Sodium:solute symporter family EOS1 PF12326.8 CRK40712.1 - 3.7e-15 56.3 5.3 8.4e-15 55.1 1.7 2.1 1 1 1 2 2 2 2 N-glycosylation protein NADH_dehy_S2_C PF06444.11 CRK40712.1 - 0.032 14.8 0.9 0.068 13.7 0.9 1.6 1 0 0 1 1 1 0 NADH dehydrogenase subunit 2 C-terminus SUI1 PF01253.22 CRK40715.1 - 3.5e-27 94.7 4.0 5.9e-27 94.0 4.0 1.3 1 0 0 1 1 1 1 Translation initiation factor SUI1 Tim44 PF04280.15 CRK40717.1 - 3.3e-05 24.0 0.7 0.00021 21.4 0.2 2.3 2 1 0 2 2 2 1 Tim44-like domain SSF PF00474.17 CRK40719.1 - 0.00076 18.5 31.0 0.0046 15.9 31.0 2.0 1 1 0 1 1 1 1 Sodium:solute symporter family Adeno_PX PF05829.12 CRK40719.1 - 6.3 6.8 10.2 3.8 7.5 0.0 3.1 3 0 0 3 3 3 0 Adenovirus late L2 mu core protein (Protein X) ATP-sulfurylase PF01747.17 CRK40721.1 - 9.9e-88 293.1 0.1 1.3e-87 292.8 0.1 1.1 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.6 CRK40721.1 - 8.4e-53 178.3 0.0 1.2e-52 177.7 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain APS_kinase PF01583.20 CRK40721.1 - 0.0019 18.1 0.0 0.0033 17.3 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase TRP PF06011.12 CRK40723.1 - 1.7e-109 366.4 16.0 2.2e-109 366.0 16.0 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 CRK40723.1 - 3.9e-32 111.5 0.0 6.5e-32 110.8 0.0 1.4 1 0 0 1 1 1 1 ML-like domain Semialdhyde_dhC PF02774.18 CRK40724.1 - 1.6e-37 129.4 0.0 2.1e-37 129.0 0.0 1.1 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 CRK40724.1 - 2.1e-27 95.9 0.0 5.9e-27 94.5 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 CRK40724.1 - 0.014 16.2 0.0 0.025 15.4 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.20 CRK40724.1 - 0.028 14.5 0.0 0.054 13.6 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus TRI12 PF06609.13 CRK40725.1 - 1e-80 271.9 24.5 1.3e-80 271.5 24.5 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 CRK40725.1 - 2.1e-18 66.4 51.5 4.6e-18 65.3 48.9 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK40725.1 - 1.1e-08 34.5 17.0 1.1e-08 34.5 17.0 3.4 2 1 1 3 3 3 1 Sugar (and other) transporter Pox_A14 PF05767.12 CRK40725.1 - 0.0015 18.6 1.3 0.012 15.8 0.3 3.0 3 0 0 3 3 3 1 Poxvirus virion envelope protein A14 BNR_2 PF13088.6 CRK40726.1 - 2e-07 30.6 0.3 0.0027 17.1 0.0 2.4 2 0 0 2 2 2 2 BNR repeat-like domain RTA1 PF04479.13 CRK40727.1 - 5.8e-57 192.6 10.4 8.1e-57 192.2 10.4 1.2 1 0 0 1 1 1 1 RTA1 like protein CoA_transf_3 PF02515.17 CRK40728.1 - 3.8e-106 355.3 0.1 4.3e-106 355.1 0.1 1.0 1 0 0 1 1 1 1 CoA-transferase family III Acetyltransf_2 PF00797.17 CRK40729.1 - 1.4e-39 136.4 0.0 1.6e-39 136.1 0.0 1.1 1 0 0 1 1 1 1 N-acetyltransferase HRI1 PF16815.5 CRK40730.1 - 9.5e-72 241.4 2.0 1.1e-71 241.3 2.0 1.0 1 0 0 1 1 1 1 Protein HRI1 DUF3370 PF11850.8 CRK40730.1 - 0.24 10.2 0.1 0.47 9.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3370) Linker_histone PF00538.19 CRK40732.1 - 1.5e-24 86.2 0.0 4.3e-24 84.7 0.0 1.8 1 0 0 1 1 1 1 linker histone H1 and H5 family Hamartin PF04388.12 CRK40732.1 - 4.6 5.8 15.4 5.4 5.5 15.4 1.1 1 0 0 1 1 1 0 Hamartin protein RR_TM4-6 PF06459.12 CRK40732.1 - 4.6 7.0 23.1 0.37 10.6 17.6 1.9 1 1 1 2 2 2 0 Ryanodine Receptor TM 4-6 DUF829 PF05705.14 CRK40735.1 - 7.6e-49 166.8 0.0 8.9e-49 166.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) DLH PF01738.18 CRK40735.1 - 0.12 11.9 1.1 0.34 10.4 0.1 2.1 2 2 0 2 2 2 0 Dienelactone hydrolase family zf-CCHC PF00098.23 CRK40736.1 - 1.9 8.7 7.1 0.38 10.9 2.4 2.1 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 CRK40736.1 - 2.4 8.0 7.4 0.25 11.1 0.8 2.2 2 0 0 2 2 2 0 Zinc knuckle Sugar_tr PF00083.24 CRK40737.1 - 2.1e-52 178.5 6.3 2.1e-52 178.5 6.3 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK40737.1 - 6.9e-36 123.9 68.8 1.8e-27 96.2 32.2 3.4 3 0 0 3 3 3 2 Major Facilitator Superfamily Sulfatase PF00884.23 CRK40737.1 - 3.6e-18 66.0 0.5 7.9e-18 64.9 0.5 1.5 1 0 0 1 1 1 1 Sulfatase DUF3425 PF11905.8 CRK40737.1 - 2.6e-09 37.1 1.3 5.2e-09 36.1 1.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Phosphodiest PF01663.22 CRK40737.1 - 7.6e-05 22.5 0.0 0.00021 21.0 0.0 1.7 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 CRK40737.1 - 0.043 12.4 0.1 0.068 11.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Lysozyme_like PF13702.6 CRK40737.1 - 0.16 11.6 0.1 0.31 10.7 0.1 1.4 1 0 0 1 1 1 0 Lysozyme-like bZIP_1 PF00170.21 CRK40737.1 - 1.2 9.3 5.1 2.6 8.2 5.1 1.6 1 0 0 1 1 1 0 bZIP transcription factor Suf PF05843.14 CRK40738.1 - 1.1e-86 291.4 3.6 4.3e-82 276.4 0.0 4.6 3 1 0 3 3 3 2 Suppressor of forked protein (Suf) TPR_14 PF13428.6 CRK40738.1 - 9.2e-05 23.0 1.1 0.011 16.5 1.2 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TAF1_subA PF14929.6 CRK40738.1 - 0.00029 20.4 0.1 0.00054 19.5 0.1 1.3 1 0 0 1 1 1 1 TAF RNA Polymerase I subunit A PAZ_siRNAbind PF12212.8 CRK40738.1 - 0.025 14.4 0.1 0.057 13.3 0.1 1.5 1 0 0 1 1 1 0 PAZ domain HrpJ PF07201.11 CRK40738.1 - 0.17 12.2 0.1 0.17 12.2 0.1 4.0 4 0 0 4 4 4 0 HrpJ-like domain BUD22 PF09073.10 CRK40738.1 - 0.73 9.1 43.3 0.019 14.3 33.6 2.1 2 0 0 2 2 2 0 BUD22 ASF1_hist_chap PF04729.13 CRK40739.1 - 2.1e-46 157.7 0.0 2.4e-46 157.5 0.0 1.0 1 0 0 1 1 1 1 ASF1 like histone chaperone DMSP_lyase PF16867.5 CRK40739.1 - 0.083 12.5 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase Suf PF05843.14 CRK40740.1 - 3.3e-72 244.0 1.0 2.3e-68 231.3 0.0 3.2 3 0 0 3 3 3 2 Suppressor of forked protein (Suf) TAF1_subA PF14929.6 CRK40740.1 - 0.00026 20.5 0.1 0.00047 19.7 0.1 1.3 1 0 0 1 1 1 1 TAF RNA Polymerase I subunit A TPR_14 PF13428.6 CRK40740.1 - 0.0073 17.0 0.8 0.38 11.7 0.7 4.0 5 0 0 5 5 5 1 Tetratricopeptide repeat PAZ_siRNAbind PF12212.8 CRK40740.1 - 0.015 15.1 0.1 0.035 13.9 0.1 1.5 1 0 0 1 1 1 0 PAZ domain Fungal_trans PF04082.18 CRK40740.1 - 0.042 12.9 0.0 0.086 11.8 0.0 1.5 1 0 0 1 1 1 0 Fungal specific transcription factor domain BUD22 PF09073.10 CRK40740.1 - 0.57 9.5 44.4 0.011 15.0 34.7 2.2 2 0 0 2 2 2 0 BUD22 Zn_clus PF00172.18 CRK40740.1 - 0.68 10.1 5.3 1.4 9.1 5.3 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain ASF1_hist_chap PF04729.13 CRK40742.1 - 8.7e-22 77.7 0.2 1.5e-21 77.0 0.2 1.4 1 0 0 1 1 1 1 ASF1 like histone chaperone RasGAP PF00616.19 CRK40743.1 - 3.6e-120 399.2 0.8 1.1e-58 198.3 0.0 3.0 3 0 0 3 3 3 2 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 CRK40743.1 - 7.4e-29 100.6 6.3 7.4e-29 100.6 6.3 3.3 4 0 0 4 4 4 1 RasGAP C-terminus Asparaginase_2 PF01112.18 CRK40743.1 - 0.17 10.9 0.0 20 4.1 0.0 2.3 2 0 0 2 2 2 0 Asparaginase FlxA PF14282.6 CRK40743.1 - 3.5 7.7 6.9 31 4.6 0.2 3.0 2 0 0 2 2 2 0 FlxA-like protein Redoxin PF08534.10 CRK40744.1 - 6.9e-28 97.2 0.0 8.2e-28 97.0 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 CRK40744.1 - 1.2e-06 28.5 0.0 1.4e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Sod_Fe_C PF02777.18 CRK40745.1 - 6.8e-31 106.5 0.0 1.3e-30 105.5 0.0 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 CRK40745.1 - 1.4e-30 105.6 0.3 4.9e-30 103.8 0.3 2.0 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Cnn_1N PF07989.11 CRK40745.1 - 7.4e-22 77.3 7.6 7.4e-22 77.3 7.6 4.1 4 0 0 4 4 4 2 Centrosomin N-terminal motif 1 Redoxin PF08534.10 CRK40745.1 - 5.6e-21 74.8 0.0 2.5e-20 72.7 0.0 2.0 2 0 0 2 2 2 1 Redoxin DUF1993 PF09351.10 CRK40745.1 - 6.4e-16 58.9 3.5 1.9e-15 57.4 0.0 3.0 3 1 0 3 3 3 1 Domain of unknown function (DUF1993) ERM PF00769.19 CRK40745.1 - 0.0027 17.5 19.9 0.0027 17.5 19.9 1.9 2 1 0 2 2 2 1 Ezrin/radixin/moesin family DegS PF05384.11 CRK40745.1 - 0.0048 16.4 3.0 0.0048 16.4 3.0 3.2 3 0 0 3 3 3 1 Sensor protein DegS YabA PF06156.13 CRK40745.1 - 0.019 15.6 14.6 0.52 11.0 0.9 3.8 2 1 1 3 3 3 0 Initiation control protein YabA Fib_alpha PF08702.10 CRK40745.1 - 0.39 10.9 6.8 0.3 11.2 3.7 2.3 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Fez1 PF06818.15 CRK40745.1 - 0.61 10.5 22.4 7.6 6.9 20.9 2.6 1 1 0 1 1 1 0 Fez1 PRKG1_interact PF15898.5 CRK40745.1 - 1.6 9.6 22.6 0.57 11.1 0.3 3.5 3 2 0 4 4 3 0 cGMP-dependent protein kinase interacting domain APC_N_CC PF16689.5 CRK40745.1 - 3 8.0 7.8 5 7.3 1.4 3.0 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain Pox_A_type_inc PF04508.12 CRK40745.1 - 3.3 7.7 6.4 1.8 8.6 2.9 2.5 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat E1-E2_ATPase PF00122.20 CRK40746.1 - 2.8e-39 134.5 7.0 1.3e-30 106.3 0.0 2.8 2 0 0 2 2 2 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 CRK40746.1 - 3.9e-24 85.4 7.7 3.9e-24 85.4 7.7 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 CRK40746.1 - 7.5e-20 72.1 0.0 2.2e-16 60.8 0.0 2.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CRK40746.1 - 7.7e-20 70.8 0.0 1.6e-19 69.7 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CRK40746.1 - 0.00047 20.0 0.1 0.0029 17.4 0.2 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Na_Pi_cotrans PF02690.15 CRK40746.1 - 0.99 9.5 6.7 0.26 11.4 2.3 2.3 2 0 0 2 2 2 0 Na+/Pi-cotransporter Sugar_tr PF00083.24 CRK40748.1 - 4.2e-71 240.2 12.0 4.2e-68 230.2 6.2 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CRK40748.1 - 3.7e-23 82.0 15.4 6.4e-23 81.2 15.5 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 CRK40748.1 - 3.3e-08 32.4 0.8 3.3e-08 32.4 0.8 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 CRK40748.1 - 1.4e-06 27.1 11.3 0.00021 20.0 0.9 2.9 2 1 1 3 3 3 3 MFS/sugar transport protein MFS_1_like PF12832.7 CRK40748.1 - 0.0093 14.9 0.0 0.02 13.8 0.0 1.5 1 0 0 1 1 1 1 MFS_1 like family DUF2182 PF09948.9 CRK40748.1 - 0.023 14.6 2.0 0.15 11.9 0.2 2.5 2 1 0 2 2 2 0 Predicted metal-binding integral membrane protein (DUF2182) Cellulase PF00150.18 CRK40749.1 - 2.4e-32 112.5 0.6 3.7e-32 111.9 0.6 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF295 PF03478.18 CRK40749.1 - 0.1 12.2 0.1 0.38 10.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF295) Cellulase PF00150.18 CRK40750.1 - 2.4e-35 122.3 1.9 3.8e-35 121.7 1.9 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_X2 PF03442.14 CRK40750.1 - 5.5e-23 80.9 0.7 4.2e-21 74.8 0.4 2.8 3 0 0 3 3 3 1 Carbohydrate binding domain X2 CBM_1 PF00734.18 CRK40750.1 - 5.7e-09 35.8 13.2 5.7e-09 35.8 13.2 1.9 2 0 0 2 2 2 1 Fungal cellulose binding domain Mrx7 PF10906.8 CRK40750.1 - 6.2e-06 26.4 0.0 1.8e-05 24.9 0.0 1.9 1 0 0 1 1 1 1 MIOREX complex component 7 Glyco_hydro_18 PF00704.28 CRK40751.1 - 2.5e-81 273.8 0.0 2.9e-81 273.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 ubiquitin PF00240.23 CRK40752.1 - 3.8e-34 116.3 0.6 7.8e-34 115.3 0.6 1.5 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.19 CRK40752.1 - 1.3e-26 92.5 1.2 1.3e-26 92.5 1.2 2.0 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 CRK40752.1 - 2.4e-16 59.3 0.7 4.8e-16 58.3 0.7 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CRK40752.1 - 2.4e-05 24.7 0.5 0.00013 22.4 0.1 2.2 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 CRK40752.1 - 0.0012 18.9 0.7 0.0026 17.8 0.7 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 CRK40752.1 - 0.0047 17.3 0.9 0.0078 16.5 0.0 1.7 1 1 1 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 CRK40752.1 - 0.0055 16.6 0.0 0.0081 16.1 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 CRK40752.1 - 0.011 16.3 0.5 0.015 15.9 0.5 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 CRK40752.1 - 0.019 15.0 1.0 5.8 7.0 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-like domain IBR PF01485.21 CRK40752.1 - 0.026 14.7 0.2 0.043 14.1 0.2 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain TUG-UBL1 PF11470.8 CRK40763.1 - 1.4e-06 28.4 0.0 3.1e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 TUG ubiquitin-like domain E1-E2_ATPase PF00122.20 CRK40763.1 - 0.0022 17.5 0.1 0.0035 16.9 0.1 1.5 1 1 0 1 1 1 1 E1-E2 ATPase DUF4294 PF14127.6 CRK40763.1 - 0.0028 17.6 0.0 0.0045 16.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4294) TRAPP PF04051.16 CRK40763.1 - 0.04 13.6 0.0 0.32 10.7 0.0 2.0 2 0 0 2 2 2 0 Transport protein particle (TRAPP) component RhoGAP-FF1 PF16512.5 CRK40771.1 - 0.0053 17.4 0.0 0.014 16.1 0.0 1.7 1 0 0 1 1 1 1 p190-A and -B Rho GAPs FF domain Utp21 PF04192.12 CRK40771.1 - 0.12 11.9 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Utp21 specific WD40 associated putative domain Amidase PF01425.21 CRK40772.1 - 4.1e-08 32.6 9.0 4.3e-08 32.6 9.0 1.0 1 0 0 1 1 1 1 Amidase Ribosomal_L29 PF00831.23 CRK40774.1 - 0.00023 21.1 6.0 0.0029 17.5 0.4 2.2 2 0 0 2 2 2 2 Ribosomal L29 protein HTH_12 PF08461.10 CRK40774.1 - 0.012 15.5 0.6 0.021 14.8 0.6 1.4 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain Pkinase PF00069.25 CRK40775.1 - 1.1e-27 97.0 0.0 1.3e-27 96.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK40775.1 - 2e-12 47.0 0.0 2.4e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CRK40775.1 - 0.018 15.0 0.0 0.04 13.8 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CRK40775.1 - 0.038 12.8 0.0 0.044 12.6 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Peptidase_S9 PF00326.21 CRK40789.1 - 3e-25 89.0 0.1 5.1e-25 88.2 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 CRK40789.1 - 0.00027 20.6 0.3 0.00034 20.3 0.3 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.12 CRK40789.1 - 0.00094 17.9 0.1 0.79 8.3 0.1 2.0 1 1 1 2 2 2 2 Acetyl xylan esterase (AXE1) TPT PF03151.16 CRK40791.1 - 2.5e-09 36.9 0.4 2.5e-09 36.9 0.4 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CRK40791.1 - 0.028 14.6 5.9 0.029 14.5 5.9 1.1 1 0 0 1 1 1 0 EamA-like transporter family zf-RING_4 PF14570.6 CRK40794.1 - 1.9e-20 72.4 11.3 3.5e-20 71.5 11.3 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.22 CRK40794.1 - 9.7e-11 41.3 0.1 3.5e-10 39.6 0.1 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.6 CRK40794.1 - 4e-07 29.8 7.4 4e-07 29.8 7.4 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CRK40794.1 - 0.0003 21.0 9.8 0.0003 21.0 9.8 1.9 2 0 0 2 2 2 1 Ring finger domain SET_assoc PF11767.8 CRK40794.1 - 0.00057 19.5 0.0 0.0012 18.4 0.0 1.5 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated Prok-RING_4 PF14447.6 CRK40794.1 - 0.00066 19.5 8.9 0.0056 16.5 4.4 2.5 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Rtf2 PF04641.12 CRK40794.1 - 0.00094 18.6 3.2 0.0022 17.4 3.2 1.6 1 0 0 1 1 1 1 Rtf2 RING-finger Nup35_RRM_2 PF14605.6 CRK40794.1 - 0.017 15.1 0.0 0.03 14.3 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Baculo_IE-1 PF05290.11 CRK40794.1 - 0.038 13.9 4.8 0.066 13.2 4.8 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-C3HC4 PF00097.25 CRK40794.1 - 0.086 12.7 10.0 0.19 11.6 10.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 CRK40794.1 - 0.1 12.7 3.8 0.27 11.4 3.8 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_5 PF14634.6 CRK40794.1 - 0.15 12.0 9.6 0.31 11.0 9.6 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CRK40794.1 - 0.18 11.7 9.6 0.43 10.5 9.6 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FYVE_2 PF02318.16 CRK40794.1 - 3.7 7.8 12.4 0.079 13.2 4.3 2.2 1 1 1 2 2 2 0 FYVE-type zinc finger Complex1_30kDa PF00329.19 CRK40795.1 - 1.3e-44 151.7 0.0 1.9e-44 151.2 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit PIP49_N PF14875.6 CRK40795.1 - 0.2 11.5 0.0 0.29 11.0 0.0 1.2 1 0 0 1 1 1 0 N-term cysteine-rich ER, FAM69 ASCH PF04266.14 CRK40796.1 - 0.15 12.6 0.0 0.35 11.5 0.0 1.6 1 0 0 1 1 1 0 ASCH domain adh_short_C2 PF13561.6 CRK40799.1 - 1.4e-35 122.9 0.9 1.7e-35 122.7 0.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRK40799.1 - 5.6e-22 78.2 0.0 7e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase NPL4 PF05021.15 CRK40812.1 - 7.1e-91 304.8 0.0 7.9e-91 304.6 0.0 1.0 1 0 0 1 1 1 1 NPL4 family CPSase_L_D2 PF02786.17 CRK40814.1 - 7.3e-85 283.8 0.0 1.2e-84 283.1 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 CRK40814.1 - 2.8e-37 127.8 0.0 1e-36 126.0 0.0 2.0 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 CRK40814.1 - 8.2e-09 35.3 0.0 1.7e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 CRK40814.1 - 1.1e-08 34.9 0.1 2.2e-08 33.9 0.1 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 CRK40814.1 - 0.00019 21.2 0.0 0.00045 20.0 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Glyoxalase_4 PF13669.6 CRK40814.1 - 0.01 16.1 0.3 13 6.1 0.1 3.3 3 0 0 3 3 3 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily UBA_6 PF18039.1 CRK40814.1 - 0.021 14.8 0.0 0.36 10.8 0.1 2.6 1 1 1 2 2 2 0 UBA-like domain ATP-grasp_5 PF13549.6 CRK40814.1 - 0.046 13.2 0.1 0.11 11.9 0.1 1.7 1 1 0 1 1 1 0 ATP-grasp domain GARS_A PF01071.19 CRK40814.1 - 0.13 12.0 0.1 0.56 10.0 0.0 2.0 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Tubulin PF00091.25 CRK40833.1 - 6.1e-46 157.1 0.0 8.8e-46 156.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CRK40833.1 - 7.6e-17 61.6 0.0 1.4e-16 60.8 0.0 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CRK40833.1 - 0.0012 18.5 0.0 0.0016 18.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 CRK40833.1 - 0.0064 15.7 0.0 0.0087 15.3 0.0 1.2 1 0 0 1 1 1 1 Tubulin like TrmK PF04816.12 CRK40833.1 - 0.096 12.2 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 tRNA (adenine(22)-N(1))-methyltransferase Sulfatase PF00884.23 CRK40850.1 - 2e-12 47.2 3.2 8.8e-12 45.0 3.2 2.0 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 CRK40850.1 - 2e-05 24.4 0.0 3.5e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase SprT-like PF10263.9 CRK40852.1 - 0.16 11.9 3.2 0.44 10.4 3.2 1.7 1 1 0 1 1 1 0 SprT-like family NAAA-beta PF15508.6 CRK40854.1 - 1.4e-13 50.9 0.1 4.5e-13 49.3 0.0 1.8 2 0 0 2 2 2 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase UPRTase PF14681.6 CRK40856.1 - 0.074 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Oxidored_FMN PF00724.20 CRK40859.1 - 3.4e-76 256.7 0.0 4.8e-76 256.2 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF1848 PF08902.11 CRK40859.1 - 0.023 14.4 0.0 0.035 13.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) AP_endonuc_2 PF01261.24 CRK40859.1 - 0.045 13.2 0.0 0.091 12.2 0.0 1.5 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Abhydrolase_6 PF12697.7 CRK40860.1 - 1.8e-09 38.5 3.1 2.6e-09 38.0 3.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CRK40860.1 - 3.7e-07 30.1 0.1 5e-07 29.6 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CRK40860.1 - 6.5e-06 25.6 0.0 1.8e-05 24.2 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF1057 PF06342.12 CRK40860.1 - 0.012 14.7 0.0 0.017 14.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Esterase PF00756.20 CRK40860.1 - 0.12 12.0 0.3 0.2 11.3 0.3 1.5 1 0 0 1 1 1 0 Putative esterase Cutinase PF01083.22 CRK40862.1 - 1.3e-50 171.8 7.8 1.5e-50 171.6 7.8 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 CRK40862.1 - 5.7e-06 26.1 1.1 8.6e-06 25.5 0.2 1.6 2 0 0 2 2 2 1 PE-PPE domain Abhydrolase_1 PF00561.20 CRK40862.1 - 0.00092 18.9 0.1 0.0013 18.4 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CRK40862.1 - 0.045 14.3 0.1 0.051 14.2 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family VirJ PF06057.11 CRK40862.1 - 0.098 12.5 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Palm_thioest PF02089.15 CRK40862.1 - 0.18 11.6 0.2 0.33 10.8 0.2 1.4 1 0 0 1 1 1 0 Palmitoyl protein thioesterase p450 PF00067.22 CRK40864.1 - 8.5e-59 199.5 0.0 2.6e-58 197.9 0.0 1.7 2 0 0 2 2 2 1 Cytochrome P450 DUF4407 PF14362.6 CRK40864.1 - 3 7.1 5.3 5.7 6.2 5.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) G_glu_transpept PF01019.21 CRK40866.1 - 6.5e-162 539.9 0.1 7.4e-162 539.7 0.1 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Hexapep PF00132.24 CRK40869.1 - 2e-09 36.8 14.3 9.5e-06 25.1 3.4 3.9 3 1 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 CRK40869.1 - 1.6e-06 27.7 10.7 0.005 16.6 2.0 3.4 3 1 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Complex1_51K PF01512.17 CRK40871.1 - 6.6e-48 162.4 0.0 1e-47 161.8 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 CRK40871.1 - 3e-29 100.9 0.9 5.7e-29 100.0 0.1 1.9 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 CRK40871.1 - 2.6e-09 36.8 0.1 7.3e-09 35.4 0.0 1.8 2 0 0 2 2 2 1 SLBB domain Peptidase_M43 PF05572.13 CRK40875.1 - 1.4e-12 47.8 0.0 2.3e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 CRK40875.1 - 0.0056 16.9 0.3 0.0082 16.3 0.3 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 CRK40875.1 - 0.039 14.5 0.0 0.06 13.9 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 CRK40875.1 - 0.18 11.4 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF1771 PF08590.10 CRK40877.1 - 0.0061 16.9 11.7 0.0061 16.9 11.7 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) CUE PF02845.16 CRK40877.1 - 0.015 15.0 0.1 0.071 12.8 0.0 2.0 2 0 0 2 2 2 0 CUE domain NUDE_C PF04880.13 CRK40877.1 - 0.049 14.1 5.6 3.7 8.0 1.8 2.5 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region Aminotran_3 PF00202.21 CRK40879.1 - 1.5e-51 175.3 0.0 5e-49 167.0 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class-III NPC1_N PF16414.5 CRK40881.1 - 7.8e-85 284.3 9.5 1.1e-84 283.8 9.5 1.2 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Patched PF02460.18 CRK40881.1 - 1.3e-78 265.0 16.5 1.3e-51 175.7 0.8 2.2 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.8 CRK40881.1 - 3.9e-52 176.2 6.7 3.9e-52 176.2 6.7 2.7 2 1 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 CRK40881.1 - 1.6e-05 24.1 33.7 0.0002 20.4 9.3 2.8 3 0 0 3 3 3 2 MMPL family Folate_rec PF03024.14 CRK40881.1 - 0.0013 18.6 2.4 0.0031 17.4 2.4 1.5 1 0 0 1 1 1 1 Folate receptor family ACR_tran PF00873.19 CRK40881.1 - 0.081 10.6 16.8 0.014 13.1 10.1 2.0 2 0 0 2 2 2 0 AcrB/AcrD/AcrF family GAS PF13851.6 CRK40883.1 - 6.4e-05 22.4 18.2 6.4e-05 22.4 18.2 7.5 3 2 3 7 7 7 4 Growth-arrest specific micro-tubule binding PKcGMP_CC PF16808.5 CRK40883.1 - 0.0021 17.9 27.3 0.027 14.3 2.7 6.4 6 0 0 6 6 6 3 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF2205 PF10224.9 CRK40883.1 - 0.0036 17.3 3.1 0.0036 17.3 3.1 7.9 9 3 2 11 11 11 1 Short coiled-coil protein FAM184 PF15665.5 CRK40883.1 - 0.0041 16.9 14.7 0.0041 16.9 14.7 7.6 2 1 5 7 7 7 2 Family with sequence similarity 184, A and B Bap31_Bap29_C PF18035.1 CRK40883.1 - 0.0067 16.4 3.6 0.0067 16.4 3.6 11.1 11 4 2 13 13 13 1 Bap31/Bap29 cytoplasmic coiled-coil domain Sugar_tr PF00083.24 CRK40887.1 - 4.4e-131 437.8 23.0 5.1e-131 437.6 23.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK40887.1 - 6.1e-22 78.0 34.6 5.6e-18 65.0 24.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4293 PF14126.6 CRK40887.1 - 0.0074 16.5 0.8 0.0074 16.5 0.8 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4293) Synaptonemal_3 PF15191.6 CRK40889.1 - 0.034 13.9 0.0 0.09 12.6 0.0 1.7 1 0 0 1 1 1 0 Synaptonemal complex central element protein 3 TMF_DNA_bd PF12329.8 CRK40889.1 - 0.58 10.2 3.9 3.1 7.9 2.0 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding TPR_MLP1_2 PF07926.12 CRK40893.1 - 1.1e-38 132.3 47.7 7e-38 129.6 29.5 18.8 7 5 10 18 18 18 5 TPR/MLP1/MLP2-like protein Flavoprotein PF02441.19 CRK40893.1 - 1.9e-17 63.4 1.0 3.5e-17 62.6 0.0 2.0 2 0 0 2 2 2 1 Flavoprotein BST2 PF16716.5 CRK40893.1 - 0.0019 18.7 1.1 0.0019 18.7 1.1 19.0 9 4 8 20 20 20 1 Bone marrow stromal antigen 2 Spc7 PF08317.11 CRK40893.1 - 0.0023 16.9 17.7 0.0023 16.9 17.7 14.6 4 3 11 15 15 15 5 Spc7 kinetochore protein PKcGMP_CC PF16808.5 CRK40893.1 - 0.045 13.6 0.1 0.045 13.6 0.1 9.7 10 0 0 10 10 10 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Pox_A_type_inc PF04508.12 CRK40893.1 - 7.8 6.5 21.2 1.5 8.8 1.7 6.4 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat LPP PF04728.13 CRK40893.1 - 9.6 6.7 0.0 9.6 6.7 0.0 19.4 18 3 1 19 19 19 0 Lipoprotein leucine-zipper Acetyltransf_1 PF00583.25 CRK40897.1 - 8.2e-10 38.9 0.0 1e-09 38.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CRK40897.1 - 9.5e-06 26.0 0.0 1.4e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CRK40897.1 - 2.2e-05 24.4 0.0 3.1e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CRK40897.1 - 0.087 12.9 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 CRK40897.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Ank_4 PF13637.6 CRK40900.1 - 0.042 14.5 0.1 2.4 8.9 0.0 3.3 4 1 0 4 4 4 0 Ankyrin repeats (many copies) TPR_MLP1_2 PF07926.12 CRK40904.1 - 3.5e-38 130.6 49.5 2.7e-37 127.7 31.0 18.9 8 5 10 19 19 19 8 TPR/MLP1/MLP2-like protein Acetyltransf_1 PF00583.25 CRK40904.1 - 2.3e-08 34.2 0.0 6.5e-08 32.8 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CRK40904.1 - 7.7e-05 23.1 0.0 0.00035 21.0 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CRK40904.1 - 9.9e-05 22.3 0.0 0.00065 19.6 0.0 2.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Rootletin PF15035.6 CRK40904.1 - 0.00087 19.4 11.8 0.00087 19.4 11.8 15.1 3 2 10 14 14 14 1 Ciliary rootlet component, centrosome cohesion PKcGMP_CC PF16808.5 CRK40904.1 - 0.037 13.9 0.1 0.037 13.9 0.1 11.4 12 0 0 12 12 12 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Acetyltransf_9 PF13527.7 CRK40904.1 - 0.051 13.7 0.0 0.51 10.4 0.0 2.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Pox_A_type_inc PF04508.12 CRK40904.1 - 6.4 6.8 23.1 1.2 9.1 1.7 7.1 7 0 0 7 7 7 0 Viral A-type inclusion protein repeat FtsJ PF01728.19 CRK40908.1 - 1.2e-61 208.0 0.0 1.5e-61 207.6 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase DEAD PF00270.29 CRK40910.1 - 3.9e-55 186.3 1.0 3.3e-43 147.5 0.1 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase Coilin_N PF15862.5 CRK40910.1 - 0.00069 19.4 21.1 0.075 12.8 2.6 4.2 2 2 0 2 2 2 2 Coilin N-terminus PGBA_C PF15437.6 CRK40910.1 - 0.014 15.7 31.0 0.56 10.6 11.2 3.2 2 0 0 2 2 2 0 Plasminogen-binding protein pgbA C-terminal PXT1 PF15214.6 CRK40910.1 - 0.11 12.9 1.1 21 5.6 0.1 2.4 2 0 0 2 2 2 0 Peroxisomal testis-specific protein 1 Nsp3_PL2pro PF12124.8 CRK40910.1 - 0.22 11.4 0.2 20 5.1 0.0 3.4 4 0 0 4 4 4 0 Coronavirus polyprotein cleavage domain SET PF00856.28 CRK40910.1 - 2 8.8 15.6 0.68 10.3 0.9 2.9 2 1 0 2 2 2 0 SET domain Protocadherin PF08374.11 CRK40910.1 - 5.5 6.9 14.4 9.9 6.1 2.6 2.7 2 0 0 2 2 2 0 Protocadherin DUF4407 PF14362.6 CRK40912.1 - 1.8 7.8 15.3 2.7 7.2 15.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SKG6 PF08693.10 CRK40914.1 - 1.3 8.5 5.8 2.6 7.5 5.8 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Glyco_transf_15 PF01793.16 CRK40916.1 - 1.5e-41 142.8 0.0 1.3e-38 133.1 0.0 3.0 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase p450 PF00067.22 CRK40918.1 - 4e-34 118.2 0.0 5.2e-34 117.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PSII_BNR PF14870.6 CRK40919.1 - 6.3e-10 38.8 8.8 0.00075 18.8 0.0 3.5 2 1 1 4 4 4 3 Photosynthesis system II assembly factor YCF48 Sortilin-Vps10 PF15902.5 CRK40919.1 - 2.8e-08 33.0 0.1 1.4e-05 24.1 0.0 2.5 2 1 1 3 3 3 3 Sortilin, neurotensin receptor 3, BNR PF02012.20 CRK40919.1 - 8.2e-06 25.1 25.2 0.76 10.0 0.3 6.6 6 0 0 6 6 6 5 BNR/Asp-box repeat BNR_2 PF13088.6 CRK40919.1 - 0.00032 20.1 0.4 0.84 8.9 0.2 3.3 1 1 0 2 2 2 2 BNR repeat-like domain Mo-co_dimer PF03404.16 CRK40919.1 - 6.7 6.7 10.0 19 5.3 0.0 4.4 3 2 2 5 5 5 0 Mo-co oxidoreductase dimerisation domain HSP70 PF00012.20 CRK40921.1 - 7e-87 292.0 2.9 7.7e-87 291.9 2.9 1.0 1 0 0 1 1 1 1 Hsp70 protein FGGY_C PF02782.16 CRK40921.1 - 0.00033 20.5 0.0 0.0011 18.7 0.0 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Peptidase_M16 PF00675.20 CRK40921.1 - 0.03 14.3 1.0 2 8.4 0.3 2.4 2 0 0 2 2 2 0 Insulinase (Peptidase family M16) zf-CHY PF05495.12 CRK40922.1 - 5.4e-18 65.2 23.4 7.9e-18 64.7 23.4 1.2 1 0 0 1 1 1 1 CHY zinc finger Glyco_hydro_12 PF01670.16 CRK40923.1 - 9.6e-12 45.3 6.1 3.9e-10 40.1 6.1 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 12 UDPG_MGDP_dh_N PF03721.14 CRK40924.1 - 2.8e-49 167.2 0.0 4.2e-36 124.3 0.0 2.5 1 1 1 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 CRK40924.1 - 2.6e-30 104.5 0.0 5.7e-30 103.4 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 CRK40924.1 - 2.2e-20 73.0 0.0 9.2e-17 61.4 0.0 2.9 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Glyco_hydro_43 PF04616.14 CRK40925.1 - 2.1e-35 122.4 2.4 2.8e-35 122.0 2.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 CRK40925.1 - 1.2e-23 83.9 0.0 1.6e-23 83.5 0.0 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Candida_ALS PF05792.13 CRK40928.1 - 1.4e-14 54.4 271.7 0.00051 20.6 12.4 16.4 15 1 0 15 15 15 10 Candida agglutinin-like (ALS) WG_beta_rep PF14903.6 CRK40928.1 - 0.012 15.9 0.0 34 4.8 0.0 3.9 3 0 0 3 3 3 0 WG containing repeat Adhesin_Dr PF04619.12 CRK40928.1 - 0.063 13.2 0.0 0.063 13.2 0.0 5.2 3 1 3 7 7 7 0 Dr-family adhesin IlvGEDA_leader PF08046.11 CRK40928.1 - 4.9 6.7 5.8 24 4.5 0.9 3.0 2 0 0 2 2 2 0 IlvGEDA operon leader peptide ADH_N PF08240.12 CRK40929.1 - 1.2e-29 102.4 1.4 1.2e-29 102.4 1.4 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CRK40929.1 - 6.1e-15 55.3 0.0 1.2e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 CRK40929.1 - 2.2e-06 27.3 0.1 4.1e-06 26.4 0.1 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_N_assoc PF13823.6 CRK40929.1 - 0.0049 16.8 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated AlaDh_PNT_C PF01262.21 CRK40929.1 - 0.027 13.8 0.1 0.043 13.1 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain MFS_1 PF07690.16 CRK40930.1 - 2.6e-25 89.1 20.7 2.6e-25 89.1 20.7 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily MliC PF09864.9 CRK40930.1 - 0.17 11.9 0.2 0.59 10.1 0.0 1.9 2 0 0 2 2 2 0 Membrane-bound lysozyme-inhibitor of c-type lysozyme Polyketide_cyc2 PF10604.9 CRK40931.1 - 4.9e-10 39.8 0.2 6.1e-10 39.5 0.2 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 CRK40932.1 - 6.4e-08 33.0 0.0 6.9e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF4521 PF15021.6 CRK40932.1 - 0.17 11.8 0.0 0.19 11.6 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4521) Zn_clus PF00172.18 CRK40933.1 - 1.2e-08 34.9 9.1 1.2e-08 34.9 9.1 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 CRK40933.1 - 3.1e-05 23.2 1.0 3.6e-05 22.9 0.2 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 CRK40933.1 - 0.0011 19.3 14.7 0.026 15.0 1.7 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CRK40933.1 - 0.0045 17.4 1.0 0.0045 17.4 1.0 3.2 2 1 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 CRK40933.1 - 0.06 14.2 18.5 0.071 14.0 0.5 3.7 4 0 0 4 4 4 0 C2H2-type zinc finger Fungal_trans_2 PF11951.8 CRK40934.1 - 0.0012 17.8 0.8 0.0012 17.8 0.8 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.25 CRK40935.1 - 1.9e-15 56.9 1.4 4.5e-13 49.1 0.2 2.4 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CRK40935.1 - 4e-10 39.6 0.3 1.6e-08 34.4 0.2 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase HSP70 PF00012.20 CRK40936.1 - 1.7e-33 115.7 0.3 2.3e-33 115.3 0.3 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CRK40936.1 - 0.0029 16.5 0.5 0.0043 15.9 0.5 1.3 1 0 0 1 1 1 1 MreB/Mbl protein IF4E PF01652.18 CRK40937.1 - 4.4e-54 182.6 0.1 5.5e-54 182.3 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E AMP-binding PF00501.28 CRK40938.1 - 7.1e-72 242.3 0.0 9.7e-72 241.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CRK40938.1 - 1.2e-11 45.5 0.2 3.4e-11 44.0 0.2 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain BolA PF01722.18 CRK40939.1 - 3.9e-30 104.0 1.9 6.3e-30 103.3 1.9 1.3 1 0 0 1 1 1 1 BolA-like protein Adeno_PV PF03910.13 CRK40939.1 - 0.72 8.5 7.5 1.1 7.9 7.5 1.3 1 0 0 1 1 1 0 Adenovirus minor core protein PV DUF5563 PF17718.1 CRK40940.1 - 0.14 11.7 1.0 0.25 10.9 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5563) Cpn60_TCP1 PF00118.24 CRK40941.1 - 5.7e-27 94.5 0.0 9.7e-27 93.7 0.0 1.3 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 CRK40941.1 - 2.3e-14 53.2 9.1 6.4e-14 51.8 9.1 1.8 1 0 0 1 1 1 1 FYVE zinc finger LHH PF14411.6 CRK40941.1 - 0.1 12.7 0.5 0.36 11.0 0.5 1.9 1 0 0 1 1 1 0 A nuclease of the HNH/ENDO VII superfamily with conserved LHH FYVE_2 PF02318.16 CRK40941.1 - 0.65 10.2 4.9 1.7 8.9 4.9 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger C1_2 PF03107.16 CRK40941.1 - 2.5 8.5 11.5 2.4 8.6 8.5 2.3 2 0 0 2 2 2 0 C1 domain VPS28 PF03997.12 CRK40942.1 - 2.6e-67 226.2 0.1 3.1e-67 225.9 0.1 1.1 1 0 0 1 1 1 1 VPS28 protein PIP5K PF01504.18 CRK40944.1 - 3.3e-28 98.7 0.5 1.7e-24 86.5 0.0 2.4 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Adap_comp_sub PF00928.21 CRK40945.1 - 5.1e-22 78.5 0.0 6.3e-22 78.2 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CRK40945.1 - 0.00012 22.0 0.0 0.00016 21.6 0.0 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF2153 PF09921.9 CRK40945.1 - 0.11 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2153) Galactosyl_T PF01762.21 CRK40946.1 - 1e-06 28.7 0.0 1.4e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase Drf_GBD PF06371.13 CRK40952.1 - 2e-51 174.2 0.0 2.9e-51 173.7 0.0 1.2 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain MMtag PF10159.9 CRK40952.1 - 2.2e-32 111.2 0.8 5.2e-32 110.0 0.8 1.7 1 0 0 1 1 1 1 Multiple myeloma tumor-associated SUIM_assoc PF16619.5 CRK40952.1 - 0.19 11.8 1.0 0.37 10.9 1.0 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 tRNA-synt_1 PF00133.22 CRK40960.1 - 2.6e-82 277.0 0.0 2.9e-82 276.8 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 CRK40960.1 - 0.045 12.5 0.2 0.062 12.0 0.2 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 CRK40960.1 - 0.046 13.2 0.1 0.41 10.1 0.1 2.2 1 1 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 Peptidase_C97 PF05903.14 CRK40963.1 - 1.2e-33 116.1 0.0 1.5e-33 115.8 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain DUF778 PF05608.12 CRK40963.1 - 0.023 15.1 0.0 0.026 14.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF778) LRAT PF04970.13 CRK40963.1 - 0.06 13.7 0.1 0.086 13.2 0.1 1.2 1 0 0 1 1 1 0 Lecithin retinol acyltransferase Ribosomal_S11 PF00411.19 CRK40964.1 - 7.4e-05 23.1 0.0 9.1e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 ERG4_ERG24 PF01222.17 CRK40966.1 - 3.4e-107 358.9 12.0 3.8e-107 358.7 12.0 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family YdjM PF04307.14 CRK40966.1 - 0.74 9.1 4.2 1.4 8.2 0.9 2.3 2 0 0 2 2 2 0 LexA-binding, inner membrane-associated putative hydrolase Hydrolase_4 PF12146.8 CRK40976.1 - 7.4e-14 51.6 0.1 8.3e-14 51.4 0.1 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CRK40976.1 - 6.2e-10 39.1 0.0 7.1e-10 38.9 0.0 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CRK40976.1 - 2.9e-05 24.8 0.0 3.5e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.12 CRK40976.1 - 5.9e-05 21.9 0.1 0.0028 16.4 0.0 2.0 1 1 1 2 2 2 1 Acetyl xylan esterase (AXE1) DUF818 PF05677.12 CRK40976.1 - 8.9e-05 21.6 0.0 0.00011 21.4 0.0 1.0 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) PGAP1 PF07819.13 CRK40976.1 - 0.0014 18.4 0.2 0.047 13.4 0.0 2.0 2 0 0 2 2 2 1 PGAP1-like protein Peptidase_S9 PF00326.21 CRK40976.1 - 0.0015 18.0 0.0 0.002 17.6 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 CRK40976.1 - 0.0018 18.2 0.1 0.0024 17.8 0.1 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 CRK40976.1 - 0.0057 16.2 0.0 0.0085 15.7 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 CRK40976.1 - 0.012 15.6 0.0 0.016 15.2 0.0 1.1 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.20 CRK40976.1 - 0.013 15.2 0.1 0.019 14.6 0.1 1.2 1 0 0 1 1 1 0 Putative esterase Lipase_3 PF01764.25 CRK40976.1 - 0.014 15.3 0.0 0.015 15.1 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 3) Peptidase_S15 PF02129.18 CRK40976.1 - 0.033 13.8 0.0 0.036 13.7 0.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_5 PF12695.7 CRK40976.1 - 0.04 13.7 0.0 0.055 13.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2974 PF11187.8 CRK40976.1 - 0.059 12.9 0.2 0.083 12.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF1057 PF06342.12 CRK40976.1 - 0.074 12.1 0.1 0.086 11.9 0.1 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) LIDHydrolase PF10230.9 CRK40976.1 - 0.11 12.0 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Thioesterase PF00975.20 CRK40976.1 - 0.15 12.1 0.0 0.18 11.9 0.0 1.1 1 0 0 1 1 1 0 Thioesterase domain Peptidase_S28 PF05577.12 CRK40976.1 - 0.16 10.7 0.0 0.25 10.1 0.0 1.3 1 1 0 1 1 1 0 Serine carboxypeptidase S28 PRK PF00485.18 CRK40977.1 - 0.064 13.0 0.0 0.084 12.6 0.0 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Lipase_GDSL_2 PF13472.6 CRK40978.1 - 1.9e-17 64.2 0.5 4.4e-17 63.0 0.5 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 CRK40978.1 - 8.4e-12 45.5 0.0 1e-11 45.2 0.0 1.0 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase SecY PF00344.20 CRK40983.1 - 5.7e-51 173.6 1.0 5.7e-51 173.6 1.0 1.4 2 0 0 2 2 2 1 SecY translocase QCR10 PF09796.9 CRK40983.1 - 0.033 14.3 0.3 5.2 7.2 0.0 2.8 3 0 0 3 3 3 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) SMC_N PF02463.19 CRK40984.1 - 4.1e-14 52.5 3.5 1.8e-13 50.5 3.5 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain DivIC PF04977.15 CRK40984.1 - 2.3 8.1 8.5 0.17 11.6 2.2 2.4 2 1 1 3 3 3 0 Septum formation initiator bZIP_2 PF07716.15 CRK40984.1 - 3.9 7.6 8.7 0.25 11.5 0.9 2.8 2 1 1 3 3 3 0 Basic region leucine zipper zf-C2H2_4 PF13894.6 CRK40986.1 - 0.0082 16.9 4.8 0.0082 16.9 4.8 1.8 1 1 1 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.26 CRK40986.1 - 0.053 14.0 6.3 0.053 14.0 6.3 1.8 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CRK40986.1 - 0.061 13.8 7.4 3.3 8.3 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger double domain Nas2_N PF18265.1 CRK40990.1 - 4.9e-28 96.9 0.1 6.4e-28 96.5 0.1 1.2 1 0 0 1 1 1 1 Nas2 N_terminal domain Dynamin_M PF01031.20 CRK40992.1 - 2.6e-110 368.1 0.0 4e-110 367.5 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 CRK40992.1 - 1.6e-56 190.9 0.0 3.1e-56 190.0 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 CRK40992.1 - 3.5e-10 39.9 0.1 3.5e-10 39.9 0.1 2.2 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 CRK40992.1 - 7.4e-05 22.8 0.4 0.00056 20.0 0.4 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Rad60-SLD PF11976.8 CRK40993.1 - 1.8e-19 69.3 0.1 2.2e-19 69.1 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 CRK40993.1 - 8e-10 38.3 0.0 9.2e-10 38.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family DUF5003 PF16394.5 CRK40993.1 - 0.05 12.7 0.0 0.053 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5003) Nup84_Nup100 PF04121.13 CRK40994.1 - 7.8e-171 569.8 3.5 9.7e-171 569.5 3.5 1.0 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 NRN1 PF15056.6 CRK40994.1 - 0.15 12.2 0.1 0.95 9.6 0.1 2.3 2 0 0 2 2 2 0 Neuritin protein family DHR10 PF18595.1 CRK40994.1 - 2 8.5 4.3 19 5.4 0.4 3.4 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain Mod_r PF07200.13 CRK40995.1 - 5.7e-21 75.2 5.8 1.2e-20 74.1 5.8 1.5 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein F-box-like PF12937.7 CRK40995.1 - 5.2e-07 29.5 1.9 8.8e-07 28.7 0.1 2.3 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 CRK40995.1 - 5.2e-06 26.2 1.9 5.3e-06 26.2 0.1 2.0 2 0 0 2 2 2 1 F-box domain HalX PF08663.10 CRK40995.1 - 0.069 13.5 1.3 1.2 9.5 0.0 2.6 2 0 0 2 2 2 0 HalX domain V-ATPase_C PF03223.15 CRK40996.1 - 2.5e-124 415.5 0.0 2.8e-124 415.3 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C APS_kinase PF01583.20 CRK40997.1 - 2.4e-71 238.7 0.0 4e-71 238.0 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase CBF PF03914.17 CRK40997.1 - 6.6e-50 169.5 0.4 7.1e-49 166.1 0.4 2.4 2 0 0 2 2 2 1 CBF/Mak21 family AAA_33 PF13671.6 CRK40997.1 - 2.3e-05 24.6 0.0 6e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CRK40997.1 - 0.0001 22.9 0.0 0.00027 21.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 CRK40997.1 - 0.0082 15.6 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Pkinase PF00069.25 CRK40999.1 - 7.4e-55 186.1 0.0 9.9e-55 185.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK40999.1 - 4.1e-41 141.0 0.0 6.2e-41 140.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CRK40999.1 - 0.00088 18.7 0.0 0.021 14.1 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CRK40999.1 - 0.0071 15.2 0.0 0.022 13.6 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 CRK40999.1 - 0.012 15.5 0.0 0.24 11.3 0.0 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CRK40999.1 - 0.048 12.6 0.0 0.77 8.6 0.0 2.1 2 0 0 2 2 2 0 Haspin like kinase domain Kdo PF06293.14 CRK40999.1 - 0.24 10.8 0.0 1 8.7 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family SNase PF00565.17 CRK41000.1 - 1.7e-23 83.1 0.0 2.6e-23 82.6 0.0 1.3 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Complex1_49kDa PF00346.19 CRK41001.1 - 4.4e-125 416.2 0.0 5.9e-125 415.8 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 CRK41001.1 - 0.0099 14.8 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 Nickel-dependent hydrogenase FAD_binding_3 PF01494.19 CRK41002.1 - 3.7e-15 56.0 0.1 2.7e-11 43.3 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 CRK41002.1 - 7.1e-05 22.0 0.1 0.0012 18.0 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein SE PF08491.10 CRK41002.1 - 0.00035 19.7 0.0 0.00054 19.1 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase NAD_binding_9 PF13454.6 CRK41002.1 - 0.003 17.6 0.0 0.0067 16.4 0.0 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 CRK41002.1 - 0.0081 15.4 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CRK41002.1 - 0.011 15.3 0.1 0.19 11.2 0.0 2.2 1 1 1 2 2 2 0 FAD dependent oxidoreductase K_oxygenase PF13434.6 CRK41002.1 - 0.014 14.6 0.0 0.025 13.7 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 CRK41002.1 - 0.025 14.8 0.0 0.074 13.3 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CRK41002.1 - 0.045 13.0 0.0 0.31 10.2 0.0 2.0 2 0 0 2 2 2 0 Thi4 family Trp_halogenase PF04820.14 CRK41002.1 - 0.076 11.9 0.0 0.7 8.7 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase MSC PF09402.10 CRK41003.1 - 1.7e-115 386.1 0.0 2.1e-115 385.8 0.0 1.1 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.7 CRK41003.1 - 1.1e-17 63.4 0.1 2.4e-17 62.3 0.1 1.6 1 0 0 1 1 1 1 HeH/LEM domain Thymopoietin PF08198.11 CRK41003.1 - 0.0012 18.4 0.0 0.0031 17.1 0.0 1.6 1 0 0 1 1 1 1 Thymopoietin protein Mt_ATP-synt_B PF05405.14 CRK41004.1 - 8.8e-54 181.5 6.2 1.1e-53 181.2 6.2 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Dak2 PF02734.17 CRK41004.1 - 0.2 11.6 2.7 0.41 10.5 1.8 1.8 1 1 1 2 2 2 0 DAK2 domain CBF PF03914.17 CRK41005.1 - 1.5e-33 116.2 1.7 2.6e-33 115.4 0.2 2.0 2 0 0 2 2 2 1 CBF/Mak21 family CorA PF01544.18 CRK41006.1 - 9.5e-33 113.8 1.3 6.5e-32 111.0 1.3 2.2 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein COPIIcoated_ERV PF07970.12 CRK41007.1 - 5.1e-87 291.4 0.0 6.6e-87 291.0 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter CSTF2_hinge PF14327.6 CRK41007.1 - 1.4e-32 112.0 2.8 2.8e-32 111.0 2.8 1.5 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 ERGIC_N PF13850.6 CRK41007.1 - 7.7e-30 103.1 0.1 2.1e-29 101.7 0.0 1.8 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) RRM_1 PF00076.22 CRK41007.1 - 3.8e-21 74.7 0.0 6.7e-21 73.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 CRK41007.1 - 6.4e-11 41.7 3.4 6.4e-11 41.7 3.4 2.9 4 0 0 4 4 4 1 Transcription termination and cleavage factor C-terminal Spo7_2_N PF15407.6 CRK41007.1 - 0.049 13.3 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Sporulation protein family 7 RRM_7 PF16367.5 CRK41007.1 - 0.1 12.7 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif Sel1 PF08238.12 CRK41008.1 - 1e-11 45.1 5.6 0.022 15.5 1.7 3.7 3 0 0 3 3 3 3 Sel1 repeat Proteasome PF00227.26 CRK41009.1 - 2.6e-47 160.8 0.1 3.4e-47 160.4 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 CRK41009.1 - 1.2e-12 47.0 0.1 1.2e-12 47.0 0.1 1.9 3 0 0 3 3 3 1 Proteasome beta subunits C terminal NUP214 PF16755.5 CRK41010.1 - 3e-08 33.3 0.0 2.1e-07 30.5 0.0 2.0 1 1 0 1 1 1 1 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 ANAPC4_WD40 PF12894.7 CRK41010.1 - 0.00013 22.2 0.0 0.00047 20.4 0.0 1.9 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain DUF4527 PF15030.6 CRK41010.1 - 0.0083 15.6 2.6 0.034 13.6 2.6 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4527) FTA4 PF13093.6 CRK41010.1 - 0.025 14.5 2.0 0.054 13.4 2.0 1.5 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF1664 PF07889.12 CRK41010.1 - 0.96 9.5 2.2 2 8.4 0.6 2.3 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) zf-C2H2 PF00096.26 CRK41013.1 - 9.9e-10 38.3 11.5 2.3e-05 24.6 4.5 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CRK41013.1 - 3.1e-09 36.9 13.8 4.9e-05 23.6 0.5 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 CRK41013.1 - 9.7e-07 29.1 11.1 0.0013 19.4 3.2 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 CRK41013.1 - 6.8e-06 26.3 1.3 1.8e-05 24.9 1.3 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 CRK41013.1 - 0.00012 22.0 2.4 0.00012 22.0 2.4 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CRK41013.1 - 0.00077 19.7 1.8 0.00077 19.7 1.8 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 CRK41013.1 - 0.038 14.3 2.4 0.047 14.0 1.2 1.7 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.6 CRK41013.1 - 0.14 12.1 4.7 3 7.9 0.4 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 CRK41013.1 - 0.72 9.7 8.3 7.2 6.5 1.2 2.7 2 0 0 2 2 2 0 zinc-finger C2H2-type DRMBL PF07522.14 CRK41015.1 - 9.8e-35 119.1 0.0 1.8e-34 118.2 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 CRK41015.1 - 0.00011 21.8 0.0 0.00022 20.8 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Rax2 PF12768.7 CRK41017.1 - 3.1e-74 249.1 5.8 5.1e-74 248.4 0.0 3.9 5 0 0 5 5 5 1 Cortical protein marker for cell polarity GTP_EFTU_D4 PF14578.6 CRK41017.1 - 0.054 13.4 0.2 1.5 8.8 0.2 2.5 2 0 0 2 2 2 0 Elongation factor Tu domain 4 DUF756 PF05506.12 CRK41019.1 - 0.041 14.8 1.7 0.65 10.9 0.5 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF756) He_PIG PF05345.12 CRK41019.1 - 2.7 8.3 10.1 13 6.1 2.8 3.4 4 0 0 4 4 4 0 Putative Ig domain P34-Arc PF04045.14 CRK41021.1 - 8.1e-90 300.7 2.1 7.2e-76 255.1 1.5 2.1 1 1 1 2 2 2 2 Arp2/3 complex, 34 kD subunit p34-Arc ARPC4 PF05856.12 CRK41021.1 - 0.067 12.8 0.1 0.37 10.4 0.1 2.0 2 0 0 2 2 2 0 ARP2/3 complex 20 kDa subunit (ARPC4) WD40 PF00400.32 CRK41022.1 - 3e-47 157.6 32.3 3.2e-06 27.8 0.3 12.3 13 1 0 13 13 13 9 WD domain, G-beta repeat Utp12 PF04003.12 CRK41022.1 - 9.3e-20 70.9 0.4 1.8e-19 70.0 0.4 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family LSM PF01423.22 CRK41022.1 - 1.3e-16 60.0 0.4 2.9e-16 58.9 0.4 1.6 1 0 0 1 1 1 1 LSM domain ANAPC4_WD40 PF12894.7 CRK41022.1 - 8e-16 58.1 7.5 0.031 14.6 0.0 9.0 5 2 6 11 11 11 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CRK41022.1 - 9.3e-07 28.1 0.7 0.56 9.1 0.0 5.0 4 1 0 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 CRK41022.1 - 0.00073 19.0 0.1 6 6.1 0.0 3.4 3 0 0 3 3 3 2 WD40-like domain Nup160 PF11715.8 CRK41022.1 - 0.00079 18.2 0.0 0.28 9.8 0.0 4.1 5 0 0 5 5 5 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 CRK41022.1 - 0.0028 16.5 2.8 0.92 8.2 0.0 4.5 3 2 1 5 5 5 1 Nup133 N terminal like eIF2A PF08662.11 CRK41022.1 - 0.038 13.9 0.1 1.8 8.4 0.0 3.4 3 1 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Hfq PF17209.3 CRK41022.1 - 0.13 12.0 0.0 0.33 10.6 0.0 1.7 1 0 0 1 1 1 0 Hfq protein Alg6_Alg8 PF03155.15 CRK41025.1 - 8.9e-122 407.5 25.1 3.8e-77 260.3 10.9 2.1 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family OGG_N PF07934.12 CRK41025.1 - 2.9e-34 117.7 0.1 6.1e-34 116.7 0.1 1.6 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain SF3b1 PF08920.10 CRK41025.1 - 1.6e-26 93.1 4.2 1.6e-26 93.1 4.2 2.2 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HhH-GPD PF00730.25 CRK41025.1 - 7.1e-15 55.4 0.0 1.9e-14 54.0 0.0 1.7 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HEAT_EZ PF13513.6 CRK41025.1 - 1.1e-09 38.5 0.6 0.026 15.1 0.0 5.9 6 0 0 6 6 6 2 HEAT-like repeat HEAT_2 PF13646.6 CRK41025.1 - 5.2e-08 33.2 3.4 0.2 12.1 0.1 6.7 4 2 3 7 7 7 2 HEAT repeats HEAT PF02985.22 CRK41025.1 - 4.2e-05 23.4 4.0 22 5.6 0.1 7.1 7 0 0 7 7 7 0 HEAT repeat NUC173 PF08161.12 CRK41025.1 - 0.0017 18.0 0.2 1.8 8.2 0.0 3.4 3 0 0 3 3 3 2 NUC173 domain HHH PF00633.23 CRK41025.1 - 0.0039 17.0 0.0 0.02 14.7 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix motif DUF3385 PF11865.8 CRK41025.1 - 0.0043 17.0 0.5 0.055 13.4 0.0 3.1 3 1 0 4 4 4 1 Domain of unknown function (DUF3385) Vac14_Fab1_bd PF12755.7 CRK41025.1 - 0.053 14.1 0.1 2.4 8.8 0.0 3.4 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region DRIM PF07539.12 CRK41025.1 - 0.17 10.1 0.1 8.3 4.6 0.1 3.0 1 1 2 3 3 3 0 Down-regulated in metastasis BRO1 PF03097.18 CRK41027.1 - 6.5e-11 41.6 0.0 9.1e-05 21.4 0.0 3.0 2 1 0 3 3 3 2 BRO1-like domain ThiC-associated PF13667.6 CRK41027.1 - 0.018 14.9 0.1 4.9 7.0 0.0 2.5 2 0 0 2 2 2 0 ThiC-associated domain HTH_40 PF14493.6 CRK41027.1 - 0.05 14.1 0.1 20 5.7 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain CTK3_C PF12350.8 CRK41027.1 - 0.44 10.7 10.3 1.6 9.0 1.8 2.6 2 0 0 2 2 2 0 CTD kinase subunit gamma CTK3 C-terminus KAR9 PF08580.10 CRK41028.1 - 2.1e-197 657.9 1.7 1.1e-170 569.6 0.4 3.7 4 0 0 4 4 4 2 Yeast cortical protein KAR9 Urocanase_C PF17392.2 CRK41028.1 - 0.001 18.6 3.1 0.57 9.6 0.4 2.4 2 0 0 2 2 2 2 Urocanase C-terminal domain KIX_2 PF16987.5 CRK41028.1 - 0.091 12.8 0.1 35 4.5 0.0 3.1 2 0 0 2 2 2 0 KIX domain ICAP-1_inte_bdg PF10480.9 CRK41028.1 - 0.17 11.8 0.0 22 4.9 0.0 2.5 2 0 0 2 2 2 0 Beta-1 integrin binding protein DUF4332 PF14229.6 CRK41028.1 - 0.19 12.0 2.8 15 5.8 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4332) Spectrin PF00435.21 CRK41028.1 - 2.9 8.4 8.9 3.2 8.3 0.0 4.3 4 1 1 5 5 5 0 Spectrin repeat TMEM171 PF15471.6 CRK41028.1 - 5.5 5.9 12.0 6.5 5.6 2.5 2.3 2 0 0 2 2 2 0 Transmembrane protein family 171 AAA PF00004.29 CRK41030.1 - 4e-43 147.0 0.0 7.5e-43 146.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 CRK41030.1 - 8.1e-12 44.9 0.0 8.5e-11 41.6 0.0 2.3 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 CRK41030.1 - 5.5e-10 38.9 0.1 1e-09 38.0 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 CRK41030.1 - 6.6e-08 33.1 0.1 7e-05 23.3 0.1 3.1 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 CRK41030.1 - 2.4e-06 27.6 0.1 5.8e-05 23.1 0.1 2.7 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CRK41030.1 - 2.6e-06 27.7 0.0 8.2e-06 26.0 0.0 1.9 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 CRK41030.1 - 6.1e-06 26.1 0.0 1.4e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 CRK41030.1 - 0.00027 20.2 0.0 0.00066 18.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 CRK41030.1 - 0.00029 21.1 0.1 0.0071 16.6 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 CRK41030.1 - 0.00094 19.7 0.0 0.0028 18.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 CRK41030.1 - 0.0013 18.0 0.0 0.0028 16.9 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_7 PF12775.7 CRK41030.1 - 0.0014 18.2 0.0 0.0028 17.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region Mg_chelatase PF01078.21 CRK41030.1 - 0.0045 16.4 0.0 0.0088 15.4 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 CRK41030.1 - 0.0047 17.3 0.0 0.011 16.1 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 CRK41030.1 - 0.0051 16.9 0.0 0.012 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CRK41030.1 - 0.0054 16.9 0.0 0.016 15.3 0.0 1.9 2 0 0 2 2 1 1 AAA domain TsaE PF02367.17 CRK41030.1 - 0.0064 16.5 0.0 0.016 15.2 0.0 1.6 2 0 0 2 2 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.6 CRK41030.1 - 0.0064 16.3 0.6 0.29 10.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain Prot_ATP_OB_N PF17758.1 CRK41030.1 - 0.0075 15.9 0.0 0.021 14.5 0.0 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB N-terminal domain IstB_IS21 PF01695.17 CRK41030.1 - 0.0091 15.7 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Sigma54_activat PF00158.26 CRK41030.1 - 0.01 15.6 0.0 0.033 13.9 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_3 PF07726.11 CRK41030.1 - 0.011 15.6 0.0 0.025 14.5 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Tektin PF03148.14 CRK41030.1 - 0.012 14.4 1.3 0.019 13.7 1.3 1.3 1 0 0 1 1 1 0 Tektin family DUF4200 PF13863.6 CRK41030.1 - 0.023 15.1 4.0 0.023 15.1 4.0 1.7 2 0 0 2 2 1 0 Domain of unknown function (DUF4200) ATPase PF06745.13 CRK41030.1 - 0.023 14.0 0.9 0.15 11.4 0.0 2.6 4 0 0 4 4 4 0 KaiC AAA_24 PF13479.6 CRK41030.1 - 0.024 14.4 0.0 0.067 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CRK41030.1 - 0.047 14.2 0.8 8.9 6.8 0.8 2.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 CRK41030.1 - 0.059 13.3 0.1 0.17 11.8 0.0 1.8 2 0 0 2 2 1 0 NACHT domain eIF-1a PF01176.19 CRK41030.1 - 0.063 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 Spc29 PF17082.5 CRK41030.1 - 0.064 13.1 0.5 0.12 12.2 0.5 1.4 1 0 0 1 1 1 0 Spindle Pole Component 29 ATPase_2 PF01637.18 CRK41030.1 - 0.066 13.1 0.2 0.41 10.5 0.0 2.3 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea PhoH PF02562.16 CRK41030.1 - 0.066 12.7 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_30 PF13604.6 CRK41030.1 - 0.072 12.8 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 CRK41030.1 - 0.098 11.9 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin DUF4140 PF13600.6 CRK41030.1 - 0.099 13.1 0.5 0.29 11.6 0.5 1.8 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) AAA_25 PF13481.6 CRK41030.1 - 0.1 12.2 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 CRK41030.1 - 0.11 12.8 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 CRK41030.1 - 0.14 11.2 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DivIC PF04977.15 CRK41030.1 - 0.22 11.3 2.1 2.9 7.7 0.6 2.7 2 0 0 2 2 2 0 Septum formation initiator SIS PF01380.22 CRK41031.1 - 1.4e-59 199.6 0.3 6.6e-32 110.1 0.1 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 CRK41031.1 - 4.4e-18 65.8 0.0 8.7e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 CRK41031.1 - 7.7e-11 42.0 0.0 1.9e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 CRK41031.1 - 0.0012 17.9 0.0 0.002 17.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.6 CRK41031.1 - 0.051 13.6 0.0 1.4 8.9 0.0 2.6 2 1 0 2 2 2 0 SIS domain Proteasome PF00227.26 CRK41032.1 - 3.3e-25 88.7 0.1 9.8e-13 48.0 0.0 2.1 2 0 0 2 2 2 2 Proteasome subunit HMG_box PF00505.19 CRK41034.1 - 6.2e-08 32.9 7.7 7.8e-06 26.2 1.2 3.4 2 1 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 CRK41034.1 - 5.1e-07 30.2 3.6 3.4e-05 24.3 0.1 2.9 2 0 0 2 2 2 2 HMG-box domain Translin PF01997.16 CRK41034.1 - 0.97 9.4 6.9 0.48 10.4 0.2 2.4 2 0 0 2 2 2 0 Translin family PTSIIB_sorb PF03830.15 CRK41034.1 - 1.1 9.5 4.7 0.46 10.7 1.1 2.1 2 1 1 3 3 3 0 PTS system sorbose subfamily IIB component 3Beta_HSD PF01073.19 CRK41035.1 - 4.7e-64 216.1 0.0 5.7e-64 215.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 CRK41035.1 - 1.3e-33 116.5 0.1 1.8e-33 116.0 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CRK41035.1 - 1.1e-18 67.8 0.0 1.8e-17 63.8 0.0 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 CRK41035.1 - 4.6e-17 62.1 0.1 5.8e-17 61.7 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 CRK41035.1 - 9.2e-13 47.9 0.3 2.1e-10 40.2 0.3 2.2 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 CRK41035.1 - 1.6e-12 47.7 0.4 2.4e-12 47.1 0.4 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 CRK41035.1 - 1.3e-09 37.6 0.1 4.5e-09 35.9 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 CRK41035.1 - 0.0005 20.0 0.9 0.0022 17.9 0.9 2.0 1 1 0 1 1 1 1 KR domain NAD_binding_3 PF03447.16 CRK41035.1 - 0.024 15.3 0.1 0.066 13.9 0.0 1.8 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain DUF2243 PF10002.9 CRK41035.1 - 0.027 14.6 0.1 0.1 12.7 0.1 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2243) RhoGAP PF00620.27 CRK41036.1 - 6.8e-34 116.9 0.0 1.3e-33 116.0 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 CRK41036.1 - 4.8e-13 49.1 17.2 2.5e-06 27.6 0.7 2.8 3 0 0 3 3 3 2 LIM domain C1_1 PF00130.22 CRK41036.1 - 0.43 10.5 15.9 0.15 12.0 1.5 3.4 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) NinD PF17466.2 CRK41036.1 - 0.78 9.9 6.6 0.27 11.3 1.5 2.6 2 0 0 2 2 2 0 Family of unknown function Yippee-Mis18 PF03226.14 CRK41036.1 - 1.3 9.2 6.5 1.1 9.5 0.9 3.0 2 1 1 3 3 3 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Desulfoferrod_N PF06397.12 CRK41036.1 - 3.4 7.4 6.3 0.56 9.9 0.2 2.6 3 0 0 3 3 3 0 Desulfoferrodoxin, N-terminal domain DZR PF12773.7 CRK41036.1 - 4.1 7.5 18.2 1.1 9.4 1.1 3.0 2 1 0 2 2 2 0 Double zinc ribbon PRCC PF10253.9 CRK41037.1 - 0.084 13.7 13.9 0.093 13.5 13.9 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting MSP1_C PF07462.11 CRK41037.1 - 4.8 5.7 6.5 5.5 5.6 6.5 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Hamartin PF04388.12 CRK41037.1 - 8.1 5.0 9.9 8.2 5.0 9.9 1.0 1 0 0 1 1 1 0 Hamartin protein DEAD PF00270.29 CRK41038.1 - 2.7e-17 63.1 0.0 6e-17 62.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CRK41038.1 - 1.2e-05 25.3 0.0 2e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CRK41039.1 - 6.1e-07 29.8 0.0 2.6e-06 27.8 0.0 2.2 2 1 0 2 2 2 1 Helicase conserved C-terminal domain Pox_L5 PF04872.13 CRK41039.1 - 0.037 13.9 0.1 0.16 11.9 0.0 2.2 3 0 0 3 3 3 0 Poxvirus L5 protein family HHH_5 PF14520.6 CRK41039.1 - 0.086 13.5 0.0 0.28 11.8 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain Abhydrolase_1 PF00561.20 CRK41040.1 - 7.4e-10 38.9 0.0 1.3e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CRK41040.1 - 1.7e-07 30.8 0.0 4.8e-07 29.3 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Esterase PF00756.20 CRK41040.1 - 0.0067 16.1 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.7 CRK41040.1 - 0.0084 16.7 12.6 0.41 11.2 12.6 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 CRK41040.1 - 0.13 11.7 0.0 0.49 9.8 0.0 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF5429 PF17494.2 CRK41041.1 - 0.085 12.9 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5429) EF-hand_4 PF12763.7 CRK41052.1 - 2.8e-10 40.1 0.0 4.6e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand DUF1720 PF08226.11 CRK41052.1 - 0.46 10.9 39.4 3.2 8.2 25.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1720) SCP2 PF02036.17 CRK41054.1 - 1.7e-21 76.6 0.2 3.6e-21 75.5 0.2 1.6 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 CRK41054.1 - 7.9e-06 26.2 0.1 1.7e-05 25.1 0.1 1.6 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.6 CRK41054.1 - 0.026 14.9 0.0 0.058 13.8 0.0 1.6 1 0 0 1 1 1 0 Sterol carrier protein domain Glyco_hydro_31 PF01055.26 CRK41070.1 - 7.6e-99 331.8 0.1 8.7e-99 331.7 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 MRP-L20 PF12824.7 CRK41086.1 - 2e-52 177.7 4.0 2.3e-52 177.5 4.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Neugrin PF06413.11 CRK41086.1 - 0.00032 20.8 0.0 0.00052 20.1 0.0 1.3 1 0 0 1 1 1 1 Neugrin RasGAP PF00616.19 CRK41088.1 - 3.9e-14 52.9 0.0 1.8e-07 31.1 0.0 2.1 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase GCP_C_terminal PF04130.13 CRK41105.1 - 2.8e-31 109.2 0.0 2.9e-31 109.1 0.0 1.0 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal SAGA-Tad1 PF12767.7 CRK41107.1 - 1.6e-20 73.9 0.0 2.1e-20 73.5 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit AAA PF00004.29 CRK41122.1 - 2.2e-22 79.9 0.0 3.9e-22 79.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) 2-oxogl_dehyd_N PF16078.5 CRK41122.1 - 4e-20 71.1 1.1 7.5e-20 70.2 1.1 1.5 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus AAA_lid_3 PF17862.1 CRK41122.1 - 3.5e-07 29.9 0.3 7e-07 28.9 0.3 1.5 1 0 0 1 1 1 1 AAA+ lid domain E1_dh PF00676.20 CRK41122.1 - 9.3e-06 24.8 0.0 1.4e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Aminotran_3 PF00202.21 CRK41136.1 - 1.9e-95 320.0 0.0 2.1e-95 319.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 CRK41136.1 - 2.8e-05 23.5 0.0 5.4e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 CRK41136.1 - 0.15 11.2 0.0 0.26 10.4 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II AAA_lid_5 PF17865.1 CRK41146.1 - 9.2e-10 38.6 0.0 1.4e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Midasin AAA lid domain AAA_5 PF07728.14 CRK41146.1 - 3.1e-07 30.5 0.0 5.3e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Dynein_heavy PF03028.15 CRK41146.1 - 4.7e-05 23.5 0.0 7.7e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain AAA_6 PF12774.7 CRK41146.1 - 0.038 13.0 0.0 0.052 12.5 0.0 1.1 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region Roughex PF06020.11 CRK41146.1 - 0.43 9.6 9.1 0.58 9.2 9.1 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Glyco_transf_90 PF05686.12 CRK41148.1 - 8.1e-06 25.0 0.0 0.0069 15.3 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 90 T2SSK PF03934.13 CRK41148.1 - 0.31 10.4 0.9 0.4 10.0 0.9 1.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein K Sugar_tr PF00083.24 CRK41149.1 - 3.5e-31 108.5 1.2 3.9e-31 108.4 1.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK41149.1 - 9.1e-08 31.4 5.5 1.1e-07 31.1 5.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Cnn_1N PF07989.11 CRK41160.1 - 8.6e-50 166.8 16.1 2.8e-26 91.5 4.1 29.3 18 10 8 27 27 27 3 Centrosomin N-terminal motif 1 PACT_coil_coil PF10495.9 CRK41160.1 - 1.2e-16 61.0 0.1 1.2e-16 61.0 0.1 6.9 7 0 0 7 7 7 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein Spc7 PF08317.11 CRK41160.1 - 6.4e-06 25.3 384.9 0.0027 16.7 25.4 18.5 2 2 15 17 17 17 8 Spc7 kinetochore protein DUF1932 PF09130.11 CRK41160.1 - 0.0035 17.3 11.1 0.53 10.3 0.3 5.2 2 1 1 3 3 3 2 Domain of unknown function (DUF1932) BRE1 PF08647.11 CRK41160.1 - 0.0035 17.4 12.3 0.0035 17.4 12.3 25.4 5 4 20 28 28 28 7 BRE1 E3 ubiquitin ligase Ponericin PF07442.11 CRK41160.1 - 0.045 13.8 0.0 17 5.6 0.0 2.5 2 0 0 2 2 2 0 Ponericin YaiA PF16362.5 CRK41160.1 - 0.25 11.5 2.5 30 4.8 0.2 3.4 2 0 0 2 2 2 0 YaiA protein Fez1 PF06818.15 CRK41160.1 - 2.5 8.5 373.8 0.0092 16.5 20.8 17.0 2 2 16 18 18 18 0 Fez1 Transglut_core2 PF13369.6 CRK41161.1 - 6.8e-17 61.4 0.0 1.1e-16 60.8 0.0 1.3 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.7 CRK41161.1 - 1e-09 38.1 0.6 2.1e-09 37.1 0.6 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CRK41161.1 - 1e-06 28.4 0.5 3.1e-06 26.9 0.5 1.9 1 0 0 1 1 1 1 F-box domain YccV-like PF08755.11 CRK41161.1 - 7.8e-06 26.3 0.1 0.00038 20.9 0.1 2.4 1 1 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like Elongin_A PF06881.11 CRK41161.1 - 0.051 14.1 0.0 0.094 13.3 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Peptidase_C12 PF01088.21 CRK41162.1 - 1.2e-59 201.6 0.4 1.2e-59 201.6 0.4 2.1 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Ribosomal_60s PF00428.19 CRK41162.1 - 0.0019 18.8 14.3 0.015 15.8 4.4 3.3 3 0 0 3 3 3 2 60s Acidic ribosomal protein RPA43_OB PF17875.1 CRK41162.1 - 0.13 12.8 0.4 0.44 11.2 0.1 1.9 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I DUF3017 PF11222.8 CRK41162.1 - 0.2 11.9 0.1 0.42 10.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3017) I-set PF07679.16 CRK41163.1 - 0.026 14.6 0.7 3.7 7.7 0.1 4.5 7 0 0 7 7 7 0 Immunoglobulin I-set domain DUF1918 PF08940.11 CRK41163.1 - 0.031 13.9 2.8 0.29 10.8 0.1 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF1918) Nrap_D5 PF17406.2 CRK41164.1 - 3e-58 196.2 1.1 6.9e-58 195.0 0.9 1.8 2 0 0 2 2 2 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D4 PF17405.2 CRK41164.1 - 9.7e-57 191.8 0.0 1.6e-56 191.0 0.0 1.3 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D2 PF17403.2 CRK41164.1 - 4.7e-51 172.6 0.3 6.7e-48 162.3 0.0 2.4 2 0 0 2 2 2 2 Nrap protein PAP/OAS-like domain Nrap_D3 PF17404.2 CRK41164.1 - 1.4e-44 152.0 0.0 3.4e-44 150.7 0.0 1.7 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap PF03813.14 CRK41164.1 - 3.3e-36 124.6 0.0 6.4e-36 123.7 0.0 1.5 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D6 PF17407.2 CRK41164.1 - 1.6e-32 112.6 0.0 4e-32 111.3 0.0 1.7 1 0 0 1 1 1 1 Nrap protein domain 6 DNA_pol_phi PF04931.13 CRK41164.1 - 0.0047 15.1 12.1 0.0073 14.5 12.1 1.2 1 0 0 1 1 1 1 DNA polymerase phi BUD22 PF09073.10 CRK41164.1 - 0.0067 15.8 2.3 0.011 15.1 2.3 1.2 1 0 0 1 1 1 1 BUD22 TFIIA PF03153.13 CRK41164.1 - 0.047 13.7 2.7 0.07 13.1 2.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Astro_capsid_p PF12226.8 CRK41164.1 - 0.087 12.0 4.0 0.16 11.1 4.0 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DUF2457 PF10446.9 CRK41164.1 - 0.11 11.6 13.4 0.18 10.9 13.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.12 CRK41164.1 - 0.21 9.7 6.6 0.32 9.2 6.6 1.1 1 0 0 1 1 1 0 Nop14-like family FAM176 PF14851.6 CRK41164.1 - 0.35 10.5 1.8 0.67 9.6 1.8 1.4 1 0 0 1 1 1 0 FAM176 family RXT2_N PF08595.11 CRK41164.1 - 1.3 9.1 6.4 3.1 7.8 6.4 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal Sigma70_ner PF04546.13 CRK41164.1 - 2.7 7.8 7.0 7 6.5 7.0 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region CoA_trans PF01144.23 CRK41165.1 - 1.1e-93 312.7 0.9 7.5e-58 195.5 0.0 2.1 2 0 0 2 2 2 2 Coenzyme A transferase HGWP PF03578.15 CRK41165.1 - 0.17 11.4 3.3 0.49 9.9 3.3 1.8 1 0 0 1 1 1 0 HGWP repeat Med3 PF11593.8 CRK41165.1 - 2.3 7.3 5.3 4.8 6.3 5.3 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal MAT1 PF06391.13 CRK41166.1 - 1.2 9.0 4.5 0.72 9.7 0.8 2.0 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 PP28 PF10252.9 CRK41168.1 - 5.1e-26 90.9 13.4 5.1e-26 90.9 13.4 3.1 2 1 1 3 3 3 2 Casein kinase substrate phosphoprotein PP28 CENP-B_dimeris PF09026.10 CRK41168.1 - 0.02 15.3 11.1 0.02 15.3 11.1 3.0 3 0 0 3 3 3 0 Centromere protein B dimerisation domain GTP_EFTU PF00009.27 CRK41170.1 - 2.3e-33 115.4 5.9 5.6e-32 110.9 5.9 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 CRK41170.1 - 4.4e-27 94.3 0.3 3.5e-26 91.4 0.1 2.2 2 0 0 2 2 2 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 CRK41170.1 - 1.1e-10 41.6 0.1 2.2e-10 40.6 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CRK41170.1 - 1e-05 25.5 2.1 0.00062 19.7 0.1 2.3 1 1 1 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 CRK41170.1 - 0.00012 21.7 0.4 0.00024 20.7 0.4 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B Roc PF08477.13 CRK41170.1 - 0.00025 21.3 0.6 0.0051 17.0 0.0 2.3 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CRK41170.1 - 0.0003 20.3 0.0 0.00058 19.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU_D2 PF03144.25 CRK41170.1 - 0.00046 20.5 1.3 0.26 11.7 0.6 2.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 IF2_N PF04760.15 CRK41170.1 - 0.00059 19.6 0.0 0.0015 18.3 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region SRPRB PF09439.10 CRK41170.1 - 0.00083 18.8 0.1 0.0019 17.7 0.1 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 CRK41170.1 - 0.0018 18.0 0.1 0.0043 16.8 0.1 1.7 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation GTP_EFTU_D4 PF14578.6 CRK41170.1 - 0.0042 17.0 0.6 0.023 14.6 0.2 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 4 Ras PF00071.22 CRK41170.1 - 0.011 15.3 0.2 0.024 14.2 0.2 1.5 1 0 0 1 1 1 0 Ras family MMR_HSR1_Xtn PF16897.5 CRK41170.1 - 0.041 13.9 0.1 0.091 12.8 0.1 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Cwf_Cwc_15 PF04889.12 CRK41170.1 - 5.6 6.6 28.8 6.9 6.3 15.5 3.3 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein VHS PF00790.19 CRK41171.1 - 1.5e-45 154.5 0.0 2.8e-45 153.6 0.0 1.5 1 0 0 1 1 1 1 VHS domain Alpha_adaptinC2 PF02883.20 CRK41171.1 - 4.9e-19 68.7 0.3 1.8e-18 66.8 0.0 2.0 2 0 0 2 2 2 1 Adaptin C-terminal domain GGA_N-GAT PF18308.1 CRK41171.1 - 2.1e-08 33.6 0.1 6e-08 32.2 0.1 1.7 1 0 0 1 1 1 1 GGA N-GAT domain GAT PF03127.14 CRK41171.1 - 1.6e-06 28.4 1.8 2.5e-06 27.7 0.1 2.2 2 0 0 2 2 2 1 GAT domain AP3B1_C PF14796.6 CRK41171.1 - 0.0055 17.0 0.1 0.022 15.0 0.0 2.0 2 0 0 2 2 2 1 Clathrin-adaptor complex-3 beta-1 subunit C-terminal FixG_C PF11614.8 CRK41171.1 - 0.023 14.9 0.1 0.042 14.1 0.1 1.3 1 0 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase HP_OMP_2 PF02521.14 CRK41171.1 - 0.048 12.5 0.0 0.11 11.3 0.0 1.5 2 0 0 2 2 2 0 Putative outer membrane protein Ribo_biogen_C PF04034.13 CRK41172.1 - 1.6e-48 163.6 0.0 2.2e-48 163.2 0.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 CRK41172.1 - 2.5e-10 40.0 0.7 2.5e-10 40.0 0.7 1.6 2 0 0 2 2 2 1 Possible Fer4-like domain in RNase L inhibitor, RLI FHA PF00498.26 CRK41173.1 - 2e-14 53.7 0.0 3.8e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CRK41173.1 - 0.017 15.4 0.0 0.52 10.7 0.0 2.2 1 1 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain Hce2 PF14856.6 CRK41175.1 - 6.3e-17 61.7 0.0 1.1e-16 61.0 0.0 1.4 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor AMMECR1 PF01871.17 CRK41177.1 - 1.1e-46 158.4 0.0 2.3e-46 157.4 0.0 1.5 1 1 0 1 1 1 1 AMMECR1 Miga PF10265.9 CRK41177.1 - 0.16 10.9 0.2 0.2 10.6 0.2 1.1 1 0 0 1 1 1 0 Mitoguardin adh_short PF00106.25 CRK41179.1 - 3.2e-50 170.3 0.4 6.6e-50 169.3 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK41179.1 - 2.2e-37 128.8 0.4 2.2e-37 128.8 0.4 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK41179.1 - 9.1e-12 45.2 0.1 2e-11 44.1 0.1 1.5 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 CRK41179.1 - 3.9e-09 36.4 0.0 1.8e-07 30.9 0.0 2.2 2 0 0 2 2 2 1 NmrA-like family DUF1776 PF08643.10 CRK41179.1 - 0.00015 21.2 0.0 0.00028 20.4 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 CRK41179.1 - 0.00037 20.0 0.1 0.00065 19.2 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 CRK41179.1 - 0.0035 16.5 0.1 0.0061 15.7 0.1 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain F420_oxidored PF03807.17 CRK41179.1 - 0.041 14.4 0.1 0.2 12.3 0.0 2.2 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent MscS_TM PF12794.7 CRK41181.1 - 0.016 14.1 0.1 0.03 13.2 0.1 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Sh_2 PF17512.2 CRK41181.1 - 0.037 13.8 0.1 0.15 11.9 0.1 1.8 1 1 1 2 2 2 0 Metapneumovirus Small hydrophobic protein PNP_UDP_1 PF01048.20 CRK41186.1 - 4.3e-20 72.0 0.1 2.3e-19 69.6 0.1 2.1 1 1 0 1 1 1 1 Phosphorylase superfamily HTH_40 PF14493.6 CRK41188.1 - 0.042 14.3 0.1 0.17 12.4 0.1 1.8 1 1 1 2 2 2 0 Helix-turn-helix domain HNH PF01844.23 CRK41190.1 - 0.0006 19.9 0.3 0.0021 18.2 0.3 1.9 1 1 0 1 1 1 1 HNH endonuclease Dehydratase_hem PF13816.6 CRK41191.1 - 4.1e-100 335.2 0.0 6e-100 334.6 0.0 1.2 1 0 0 1 1 1 1 Haem-containing dehydratase DIOX_N PF14226.6 CRK41191.1 - 4.1e-14 53.3 0.0 9.9e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 CRK41191.1 - 6.4e-09 36.2 0.0 1.5e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF4188 PF13826.6 CRK41191.1 - 0.00018 21.8 0.1 0.095 13.0 0.2 2.6 2 1 0 2 2 2 2 Domain of unknown function (DUF4188) RPAP1_C PF08620.10 CRK41194.1 - 2.4e-26 91.6 0.0 4.5e-26 90.7 0.0 1.5 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 CRK41194.1 - 9.4e-17 60.5 6.2 1.7e-16 59.7 6.2 1.4 1 0 0 1 1 1 1 RPAP1-like, N-terminal Pex14_N PF04695.13 CRK41194.1 - 0.0013 19.4 6.1 0.0013 19.4 6.1 1.8 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Dehydratase_hem PF13816.6 CRK41196.1 - 2.5e-100 335.9 0.0 3.4e-100 335.4 0.0 1.2 1 0 0 1 1 1 1 Haem-containing dehydratase 2OG-FeII_Oxy PF03171.20 CRK41196.1 - 2.9e-14 53.4 0.0 7.6e-14 52.0 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 CRK41196.1 - 0.00021 22.0 0.0 0.0011 19.8 0.0 2.1 1 1 1 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal DUF4188 PF13826.6 CRK41196.1 - 0.00022 21.5 0.0 0.05 13.9 0.1 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4188) DUF4880 PF16220.5 CRK41196.1 - 0.15 11.9 2.9 33 4.5 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4880) HNH PF01844.23 CRK41197.1 - 0.00062 19.9 0.3 0.0021 18.2 0.3 1.9 1 1 0 1 1 1 1 HNH endonuclease HUN PF08729.10 CRK41198.1 - 5.2e-08 32.8 0.4 1.2e-07 31.6 0.4 1.7 1 0 0 1 1 1 1 HPC2 and ubinuclein domain SpoIIIAH PF12685.7 CRK41198.1 - 5.9 6.7 13.3 3 7.6 5.1 2.4 2 0 0 2 2 2 0 SpoIIIAH-like protein SURF6 PF04935.12 CRK41199.1 - 2.1e-46 158.2 34.4 2.1e-46 158.2 34.4 4.9 2 1 1 4 4 4 1 Surfeit locus protein 6 RRP14 PF15459.6 CRK41199.1 - 3.8e-17 62.7 0.2 3.8e-17 62.7 0.2 7.7 6 2 1 7 7 7 1 60S ribosome biogenesis protein Rrp14 GPP34 PF05719.11 CRK41200.1 - 3.3e-106 353.8 2.8 1.7e-68 230.6 0.5 2.1 2 0 0 2 2 2 2 Golgi phosphoprotein 3 (GPP34) Acetyltransf_10 PF13673.7 CRK41200.1 - 0.00052 20.0 0.3 0.77 9.7 0.1 2.5 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain PRTase_3 PF15610.6 CRK41200.1 - 0.0062 15.8 0.0 3.2 6.9 0.0 2.2 2 0 0 2 2 2 2 PRTase ComF-like YccF PF03733.13 CRK41200.1 - 0.048 14.4 0.1 18 6.1 0.0 2.4 2 0 0 2 2 2 0 Inner membrane component domain AXE1 PF05448.12 CRK41200.1 - 0.099 11.3 0.0 12 4.5 0.0 2.2 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) 3HCDH_N PF02737.18 CRK41200.1 - 0.16 11.8 0.1 25 4.7 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain eIF2A PF08662.11 CRK41201.1 - 9.7e-147 485.6 0.0 3.4e-77 258.7 0.0 3.1 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 CRK41201.1 - 0.00073 20.3 4.5 3.6 8.6 0.1 4.7 6 0 0 6 6 6 2 WD domain, G-beta repeat DUF3563 PF12086.8 CRK41201.1 - 0.0067 16.1 0.0 7 6.5 0.0 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF3563) DUF5604 PF18300.1 CRK41201.1 - 0.02 14.8 0.5 12 6.0 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5604) TRAF_BIRC3_bd PF16673.5 CRK41201.1 - 0.053 13.3 1.2 7.8 6.4 0.3 2.4 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain CDV3 PF15359.6 CRK41201.1 - 0.11 12.9 1.6 18 5.8 0.1 3.0 2 0 0 2 2 2 0 Carnitine deficiency-associated protein 3 DUF1269 PF06897.12 CRK41201.1 - 0.14 12.4 0.0 39 4.6 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1269) Hs1pro-1_C PF07014.12 CRK41201.1 - 0.21 11.0 0.9 17 4.8 0.1 2.2 2 0 0 2 2 2 0 Hs1pro-1 protein C-terminus DUF3659 PF12396.8 CRK41203.1 - 8.9e-144 467.5 67.3 1.3e-18 66.7 0.1 9.5 9 0 0 9 9 9 9 Protein of unknown function (DUF3659) Apolipoprotein PF01442.18 CRK41203.1 - 0.0049 16.8 24.8 0.0049 16.8 24.8 3.7 2 1 1 3 3 3 2 Apolipoprotein A1/A4/E domain GCV_T_C PF08669.11 CRK41203.1 - 0.023 14.6 1.4 23 5.0 0.1 4.4 3 1 1 4 4 4 0 Glycine cleavage T-protein C-terminal barrel domain Phasin_2 PF09361.10 CRK41203.1 - 0.16 12.2 54.6 0.42 10.9 9.9 6.5 2 1 4 6 6 6 0 Phasin protein Asp_Glu_race_2 PF14669.6 CRK41203.1 - 0.2 11.3 0.1 2.2 7.9 0.0 2.4 2 0 0 2 2 2 0 Putative aspartate racemase DUF3659 PF12396.8 CRK41204.1 - 4.5e-14 52.1 1.8 7.4e-11 41.8 0.3 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3659) PAT1 PF09770.9 CRK41204.1 - 0.95 7.7 20.6 1.1 7.4 20.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4266 PF14086.6 CRK41204.1 - 2.4 9.2 14.5 1.2 10.1 10.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4266) Pyridoxal_deC PF00282.19 CRK41205.1 - 2e-10 40.0 0.0 3.3e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Snf7 PF03357.21 CRK41205.1 - 2.2e-07 30.7 18.4 1.1e-06 28.3 18.4 2.0 1 1 0 1 1 1 1 Snf7 Beta_elim_lyase PF01212.21 CRK41205.1 - 0.0036 16.6 0.0 0.0036 16.6 0.0 2.4 2 1 0 2 2 2 1 Beta-eliminating lyase S-AdoMet_synt_M PF02772.16 CRK41205.1 - 0.035 14.4 0.1 0.14 12.4 0.0 2.0 2 0 0 2 2 2 0 S-adenosylmethionine synthetase, central domain CDC45 PF02724.14 CRK41205.1 - 0.51 8.6 6.9 0.77 8.0 6.9 1.1 1 0 0 1 1 1 0 CDC45-like protein zf-C3HC4_2 PF13923.6 CRK41206.1 - 1.7e-11 43.7 10.1 1.7e-11 43.7 10.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CRK41206.1 - 4.1e-08 33.0 9.8 4.1e-08 33.0 9.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CRK41206.1 - 3.3e-07 30.2 7.4 3.3e-07 30.2 7.4 1.9 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 CRK41206.1 - 4e-07 29.8 11.4 2.4e-05 24.1 7.7 2.3 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 CRK41206.1 - 4.5e-07 29.6 7.5 4.5e-07 29.6 7.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CRK41206.1 - 6.1e-07 29.3 9.7 6.1e-07 29.3 9.7 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.6 CRK41206.1 - 2.6e-06 27.2 1.9 5.3e-06 26.2 1.9 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_2 PF13639.6 CRK41206.1 - 2.8e-06 27.5 9.3 2.8e-06 27.5 9.3 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 CRK41206.1 - 6.7e-05 23.0 9.1 6.7e-05 23.0 9.1 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 CRK41206.1 - 0.00014 22.1 5.0 0.00014 22.1 5.0 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger domain SAP PF02037.27 CRK41206.1 - 0.00021 20.9 0.0 0.00036 20.2 0.0 1.4 1 0 0 1 1 1 1 SAP domain zf-RING_4 PF14570.6 CRK41206.1 - 0.00081 19.1 2.0 0.00081 19.1 2.0 2.8 3 0 0 3 3 3 1 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 CRK41206.1 - 0.0017 18.5 3.6 0.0033 17.5 3.6 1.4 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-P11 PF03854.14 CRK41206.1 - 0.5 10.1 6.4 1.3 8.7 6.4 1.7 1 0 0 1 1 1 0 P-11 zinc finger zf-ANAPC11 PF12861.7 CRK41206.1 - 0.53 10.4 5.1 0.16 12.0 1.2 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Mob_synth_C PF06463.13 CRK41206.1 - 0.61 10.0 6.1 0.15 12.0 2.7 1.7 2 0 0 2 2 2 0 Molybdenum Cofactor Synthesis C zinc-ribbons_6 PF07191.12 CRK41206.1 - 5.5 7.1 11.7 13 5.9 5.5 2.5 2 0 0 2 2 2 0 zinc-ribbons CDC27 PF09507.10 CRK41207.1 - 1.2e-76 258.8 19.2 1.4e-76 258.6 19.2 1.0 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 Ribosomal_S25 PF03297.15 CRK41207.1 - 3.6 7.9 4.6 1.3 9.2 0.0 2.7 3 0 0 3 3 3 0 S25 ribosomal protein Glyco_hydro_125 PF06824.11 CRK41208.1 - 2.5e-179 596.5 0.0 2.9e-179 596.3 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) Aminotran_1_2 PF00155.21 CRK41209.1 - 7.8e-16 58.2 0.0 1.8e-15 57.0 0.0 1.5 1 1 1 2 2 2 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 CRK41209.1 - 0.02 13.7 0.0 2.3 6.9 0.0 2.2 2 0 0 2 2 2 0 Alanine-glyoxylate amino-transferase HET PF06985.11 CRK41211.1 - 4.7e-08 33.5 1.2 1.6e-05 25.3 0.0 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Glyoxalase_3 PF13468.6 CRK41212.1 - 1.2e-19 71.1 0.1 2.2e-19 70.3 0.1 1.4 1 0 0 1 1 1 1 Glyoxalase-like domain MOZ_SAS PF01853.18 CRK41213.1 - 2.6e-79 265.0 0.0 3.7e-79 264.5 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 CRK41213.1 - 9e-21 73.2 0.5 1.5e-20 72.5 0.5 1.4 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 CRK41213.1 - 2.9e-17 62.3 0.1 1e-16 60.6 0.0 2.0 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 CRK41213.1 - 0.00042 20.7 0.0 0.00093 19.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CRK41213.1 - 0.033 14.4 0.0 0.073 13.3 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Chromo PF00385.24 CRK41213.1 - 0.096 12.6 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain NPR1_interact PF15699.5 CRK41213.1 - 4.5 8.0 8.7 27 5.4 8.8 2.2 1 1 1 2 2 2 0 NPR1 interacting CMAS PF02353.20 CRK41215.1 - 4e-59 200.1 0.0 5.4e-59 199.7 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 CRK41215.1 - 1.7e-11 44.7 0.0 3.4e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CRK41215.1 - 4.5e-11 43.3 0.0 8.7e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CRK41215.1 - 1.4e-07 31.5 0.0 2.2e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK41215.1 - 4.9e-07 29.6 0.0 8.4e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 CRK41215.1 - 0.00032 20.5 0.0 0.00051 19.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 CRK41215.1 - 0.0004 21.1 0.0 0.00079 20.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.12 CRK41215.1 - 0.048 13.4 0.0 0.44 10.3 0.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_18 PF12847.7 CRK41215.1 - 0.18 11.7 0.0 0.29 11.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain RNase_H2_suC PF08615.11 CRK41216.1 - 5.4e-26 91.5 0.0 8e-26 90.9 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) MCM PF00493.23 CRK41217.1 - 1e-102 342.0 1.0 1.9e-102 341.2 1.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CRK41217.1 - 2.2e-38 130.9 0.2 4.2e-38 130.0 0.2 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CRK41217.1 - 1e-23 83.5 1.2 2.4e-23 82.3 0.6 2.0 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 CRK41217.1 - 1.9e-22 79.8 0.0 9e-22 77.6 0.0 2.3 2 0 0 2 2 2 1 MCM N-terminal domain MCM6_C PF18263.1 CRK41217.1 - 2.1e-17 63.3 0.0 5.1e-14 52.4 0.0 2.7 1 1 0 1 1 1 1 MCM6 C-terminal winged-helix domain Mg_chelatase PF01078.21 CRK41217.1 - 1.7e-07 30.8 0.0 6.3e-07 29.0 0.1 1.9 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 CRK41217.1 - 0.00051 19.8 0.0 0.0012 18.6 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 CRK41217.1 - 0.0011 18.8 0.0 0.003 17.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CRK41217.1 - 0.031 14.3 0.0 0.081 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) CCDC53 PF10152.9 CRK41217.1 - 0.23 11.8 1.0 6.7 7.1 0.1 2.7 3 0 0 3 3 3 0 Subunit CCDC53 of WASH complex F1F0-ATPsyn_F PF10791.9 CRK41218.1 - 1.2e-40 137.9 0.4 3.1e-40 136.6 0.4 1.8 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi Mucin PF01456.17 CRK41218.1 - 0.012 15.6 11.7 0.076 13.0 11.7 2.4 1 0 0 1 1 1 0 Mucin-like glycoprotein ETC_C1_NDUFA4 PF04800.12 CRK41219.1 - 1.6e-36 124.4 1.8 2.6e-36 123.8 1.8 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region Copper-bind PF00127.20 CRK41219.1 - 0.066 13.7 0.0 0.13 12.7 0.0 1.4 1 1 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family CLTH PF10607.9 CRK41220.1 - 5e-26 91.4 0.1 7.1e-26 90.9 0.1 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 CRK41220.1 - 4e-09 36.1 0.0 9.4e-09 34.9 0.0 1.7 1 0 0 1 1 1 1 LisH Pyr_redox_2 PF07992.14 CRK41221.1 - 2.8e-42 144.9 0.0 4.2e-42 144.4 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CRK41221.1 - 1.6e-12 47.8 0.0 6.5e-08 33.0 0.0 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.32 CRK41221.1 - 1.1e-06 27.7 0.2 2.5e-06 26.6 0.2 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 CRK41221.1 - 1.7e-05 24.4 0.4 4.9e-05 22.9 0.4 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 CRK41221.1 - 0.00011 21.5 0.7 0.00026 20.4 0.7 1.6 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 CRK41221.1 - 0.0002 21.8 0.3 0.00052 20.4 0.3 1.7 1 0 0 1 1 1 1 EF-hand domain pair Pyr_redox_3 PF13738.6 CRK41221.1 - 0.012 14.9 0.8 9.5 5.4 0.8 2.9 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Chitin_synth_2 PF03142.15 CRK41229.1 - 7.7e-59 199.7 1.3 9.4e-59 199.4 1.3 1.0 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 CRK41229.1 - 0.00053 19.9 0.4 0.00078 19.4 0.4 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 CRK41229.1 - 0.0066 16.4 1.8 0.016 15.2 1.8 1.7 1 1 0 1 1 1 1 Glycosyl transferase family group 2 DUF1751 PF08551.10 CRK41235.1 - 3.7e-27 94.8 4.1 3.7e-27 94.8 4.1 2.0 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Phage_holin_2_4 PF16082.5 CRK41235.1 - 0.14 11.9 0.6 0.34 10.7 0.6 1.6 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like Rhomboid PF01694.22 CRK41235.1 - 0.33 11.0 12.0 0.54 10.3 12.0 1.3 1 0 0 1 1 1 0 Rhomboid family Cpn60_TCP1 PF00118.24 CRK41237.1 - 2.9e-72 243.9 0.5 4.5e-72 243.2 0.5 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pyr_redox_2 PF07992.14 CRK41237.1 - 0.014 14.6 0.9 0.25 10.6 1.2 2.5 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF5398 PF17376.2 CRK41237.1 - 0.028 15.0 0.2 0.41 11.3 0.2 2.5 3 0 0 3 3 3 0 Family of unknown function (DUF5398) PNTB_4TM PF12769.7 CRK41237.1 - 0.075 13.5 0.0 0.15 12.6 0.0 1.4 1 0 0 1 1 1 0 4TM region of pyridine nucleotide transhydrogenase, mitoch GIT_CC PF16559.5 CRK41237.1 - 0.25 11.2 0.9 15 5.5 0.1 2.3 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Acyl-CoA_dh_M PF02770.19 CRK41239.1 - 1.3e-10 41.3 0.0 1.9e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 CRK41239.1 - 1.9e-09 37.9 0.1 3.3e-09 37.1 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 CRK41239.1 - 0.0031 18.1 0.0 0.0054 17.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 CRK41239.1 - 0.0065 16.7 0.0 0.0097 16.2 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain FA_desaturase PF00487.24 CRK41244.1 - 1.3e-10 41.6 3.1 1.5e-10 41.3 3.1 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Cellulase PF00150.18 CRK41257.1 - 7.1e-14 51.9 0.5 1.2e-13 51.2 0.5 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF4038 PF13204.6 CRK41257.1 - 1.1e-05 25.2 0.2 1.2e-05 25.2 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) DUF4434 PF14488.6 CRK41257.1 - 0.0021 18.1 0.3 0.11 12.5 0.1 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4434) Glyco_hydro_42 PF02449.15 CRK41257.1 - 0.0053 16.1 0.1 0.018 14.4 0.0 1.8 2 0 0 2 2 2 1 Beta-galactosidase Glyco_hydro_2_C PF02836.17 CRK41257.1 - 0.017 14.3 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 CRK41268.1 - 2.2e-32 112.6 0.0 2.7e-32 112.3 0.0 1.0 1 0 0 1 1 1 1 Beta galactosidase small chain WH1 PF00568.23 CRK41271.1 - 5.5e-07 29.5 0.0 5.9e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 WH1 domain DCP1 PF06058.13 CRK41271.1 - 0.065 13.2 0.0 0.072 13.0 0.0 1.1 1 0 0 1 1 1 0 Dcp1-like decapping family WD40 PF00400.32 CRK41274.1 - 0.0034 18.2 0.0 0.2 12.6 0.0 2.2 2 0 0 2 2 2 1 WD domain, G-beta repeat BBS2_Mid PF14783.6 CRK41274.1 - 0.07 13.2 0.1 0.18 11.9 0.0 1.7 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, middle region zf-C2H2 PF00096.26 CRK41283.1 - 7.9e-05 22.9 23.8 0.45 11.1 5.0 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CRK41283.1 - 0.00015 22.3 20.3 0.29 12.1 5.2 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CRK41283.1 - 0.16 12.0 8.6 2.3 8.3 3.8 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger Adeno_E3_CR2 PF02439.15 CRK41283.1 - 0.28 11.0 1.3 0.5 10.2 1.3 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Shisa PF13908.6 CRK41283.1 - 0.3 11.3 0.0 0.3 11.3 0.0 3.2 3 1 1 4 4 4 0 Wnt and FGF inhibitory regulator FAD_binding_7 PF03441.14 CRK41285.1 - 3.6e-48 163.7 1.0 5.8e-48 163.1 1.0 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 CRK41285.1 - 9.2e-20 71.3 0.0 1.6e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase 4HBT PF03061.22 CRK41286.1 - 6.7e-05 23.2 0.3 0.00017 21.9 0.3 1.7 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 CRK41286.1 - 0.044 13.9 0.0 0.092 12.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) zf-HC3 PF16827.5 CRK41286.1 - 0.069 13.4 0.2 0.069 13.4 0.2 2.4 2 1 1 3 3 3 0 zinc-finger SQS_PSY PF00494.19 CRK41287.1 - 1.4e-63 214.9 1.8 2.4e-63 214.1 1.8 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase Pirin PF02678.16 CRK41288.1 - 4.5e-25 87.7 2.2 6.1e-25 87.3 0.6 2.1 2 1 0 2 2 1 1 Pirin Amino_oxidase PF01593.24 CRK41288.1 - 5.7e-25 88.5 0.2 4.2e-22 79.1 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CRK41288.1 - 3.8e-15 55.9 0.2 2.4e-14 53.3 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CRK41288.1 - 2.4e-11 43.9 0.1 1.2e-10 41.6 0.1 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CRK41288.1 - 3.6e-10 39.5 0.1 4.2e-06 26.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CRK41288.1 - 1.8e-07 30.6 7.1 0.00013 21.2 3.0 3.7 4 0 0 4 4 4 2 FAD binding domain HI0933_like PF03486.14 CRK41288.1 - 1.4e-06 27.3 1.1 0.00093 18.0 0.9 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.27 CRK41288.1 - 0.00018 22.0 2.7 0.035 14.6 1.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CRK41288.1 - 0.00019 20.9 0.1 0.00067 19.1 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase MCRA PF06100.11 CRK41288.1 - 0.00064 18.6 0.0 0.098 11.4 0.0 2.1 2 0 0 2 2 2 1 MCRA family Pyr_redox_3 PF13738.6 CRK41288.1 - 0.0025 17.1 1.4 0.0041 16.4 1.4 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Cupin_2 PF07883.11 CRK41288.1 - 0.0059 16.3 2.2 0.63 9.8 0.3 3.1 2 1 0 2 2 2 1 Cupin domain ApbA PF02558.16 CRK41288.1 - 0.0071 16.0 0.2 0.016 14.9 0.2 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Thi4 PF01946.17 CRK41288.1 - 0.013 14.7 0.2 0.026 13.8 0.2 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 CRK41288.1 - 0.014 15.4 1.5 0.76 9.8 0.3 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 CRK41288.1 - 0.03 13.6 0.4 0.059 12.6 0.4 1.4 1 0 0 1 1 1 0 FAD binding domain YARHG PF13308.6 CRK41288.1 - 0.038 13.9 0.4 1.9 8.4 0.1 2.8 2 0 0 2 2 2 0 YARHG domain 3HCDH_N PF02737.18 CRK41288.1 - 0.043 13.7 0.8 0.074 12.9 0.8 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 CRK41288.1 - 0.066 12.3 4.4 0.082 12.0 2.0 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 CRK41288.1 - 0.09 11.8 3.9 0.071 12.1 0.7 2.2 3 0 0 3 3 3 0 Lycopene cyclase protein adh_short PF00106.25 CRK41288.1 - 0.11 11.9 1.5 0.31 10.5 1.0 1.9 2 0 0 2 2 2 0 short chain dehydrogenase GDI PF00996.18 CRK41288.1 - 0.13 10.7 0.1 8.3 4.8 0.0 2.2 2 0 0 2 2 2 0 GDP dissociation inhibitor Glyco_hydro_18 PF00704.28 CRK41289.1 - 7.1e-10 39.1 0.0 4.3e-09 36.5 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Oxysterol_BP PF01237.18 CRK41290.1 - 1.2e-134 448.9 1.4 8.6e-134 446.1 0.0 2.1 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_5 PF13857.6 CRK41290.1 - 7.5e-17 61.2 0.0 3.4e-09 36.8 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CRK41290.1 - 7.2e-15 55.4 0.0 2.5e-09 37.6 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 CRK41290.1 - 1.2e-14 54.0 0.1 2.7e-05 24.4 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 CRK41290.1 - 4.8e-13 48.0 0.1 0.00014 22.1 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 CRK41290.1 - 1.2e-12 48.1 0.0 6.7e-08 32.9 0.0 3.0 2 1 1 3 3 3 3 Ankyrin repeats (many copies) PH PF00169.29 CRK41290.1 - 7.5e-11 42.5 0.3 1.5e-10 41.5 0.3 1.6 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 CRK41290.1 - 3e-08 33.8 0.5 8e-08 32.5 0.5 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 CRK41290.1 - 0.00065 20.1 2.2 0.0018 18.7 2.2 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain 4HBT_3 PF13622.6 CRK41291.1 - 7.8e-72 242.5 5.1 9.5e-72 242.2 5.1 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 CRK41291.1 - 2.8e-16 59.5 0.0 4.5e-09 36.2 0.0 3.2 2 1 0 2 2 2 2 Acyl-CoA thioesterase 4HBT_3 PF13622.6 CRK41292.1 - 1.3e-45 156.7 0.5 1.6e-45 156.3 0.5 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 CRK41292.1 - 4.2e-16 59.0 0.0 1.2e-09 38.0 0.0 2.2 2 0 0 2 2 2 2 Acyl-CoA thioesterase Zn_clus PF00172.18 CRK41293.1 - 4e-08 33.2 11.9 8.1e-08 32.3 11.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HCO3_cotransp PF00955.21 CRK41294.1 - 3.1e-72 244.1 5.2 3.2e-38 131.8 0.0 2.1 1 1 1 2 2 2 2 HCO3- transporter family DUF3341 PF11821.8 CRK41294.1 - 0.11 12.2 0.1 0.11 12.2 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3341) Arf PF00025.21 CRK41295.1 - 2.1e-44 151.1 0.0 2.5e-44 150.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 CRK41295.1 - 1.4e-08 34.4 0.4 1.8e-05 24.1 0.0 2.5 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 CRK41295.1 - 3.2e-07 30.6 0.0 8.5e-07 29.2 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CRK41295.1 - 1.9e-06 27.6 0.0 2.4e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 CRK41295.1 - 4.8e-06 26.6 0.0 7.2e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CRK41295.1 - 0.00016 21.1 0.0 0.0002 20.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 CRK41295.1 - 0.00023 20.7 0.0 0.00029 20.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 CRK41295.1 - 0.1 12.1 0.0 9.1 5.8 0.0 2.1 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain Fungal_trans PF04082.18 CRK41298.1 - 4.7e-27 94.7 0.2 6.8e-27 94.2 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 CRK41300.1 - 1.1e-27 96.9 26.7 1.5e-27 96.5 26.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK41300.1 - 9.5e-06 24.7 15.4 2.6e-05 23.3 15.4 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 CRK41300.1 - 0.0011 18.3 6.6 0.0011 18.3 6.6 1.6 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF1445 PF07286.12 CRK41302.1 - 5.6e-21 75.0 0.1 6.4e-21 74.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1445) MMR_HSR1 PF01926.23 CRK41304.1 - 1.3e-10 41.3 0.0 2.3e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CRK41304.1 - 0.0086 16.0 0.4 0.042 13.8 0.4 2.0 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 CRK41304.1 - 0.012 15.2 0.1 0.025 14.1 0.0 1.5 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_16 PF13191.6 CRK41304.1 - 0.015 15.7 0.2 0.026 14.9 0.2 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 CRK41304.1 - 0.032 14.8 0.3 0.19 12.3 0.1 2.2 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 CRK41304.1 - 0.063 13.3 0.0 2.4 8.2 0.0 2.2 2 0 0 2 2 2 0 Dynamin family MeaB PF03308.16 CRK41304.1 - 0.11 11.5 0.9 0.17 10.8 0.1 1.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Arf PF00025.21 CRK41304.1 - 0.11 11.9 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family Roc PF08477.13 CRK41304.1 - 0.19 11.9 0.0 0.4 10.9 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase PHD PF00628.29 CRK41306.1 - 2.2e-09 37.1 2.1 4.8e-09 36.0 2.1 1.5 1 0 0 1 1 1 1 PHD-finger UIM PF02809.20 CRK41306.1 - 0.00089 19.0 3.6 0.0024 17.7 3.6 1.8 1 0 0 1 1 1 1 Ubiquitin interaction motif PHD_2 PF13831.6 CRK41306.1 - 0.002 17.6 2.6 0.0034 16.9 2.6 1.4 1 0 0 1 1 1 1 PHD-finger zf-CW PF07496.15 CRK41306.1 - 0.1 12.6 0.9 0.25 11.4 0.9 1.6 1 0 0 1 1 1 0 CW-type Zinc Finger CEBP_ZZ PF16366.5 CRK41306.1 - 0.11 12.7 4.4 0.13 12.6 1.6 2.2 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain Ribosomal_L1 PF00687.21 CRK41307.1 - 1.8e-22 80.1 0.3 7e-22 78.2 0.2 1.7 1 1 1 2 2 2 1 Ribosomal protein L1p/L10e family Salt_tol_Pase PF09506.10 CRK41307.1 - 0.11 11.2 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Glucosylglycerol-phosphate phosphatase (Salt_tol_Pase) TPP_enzyme_C PF02775.21 CRK41308.1 - 6.2e-12 45.6 0.0 8.7e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain COG2 PF06148.11 CRK41308.1 - 0.014 15.5 0.0 0.024 14.7 0.0 1.4 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Hap4_Hap_bind PF10297.9 CRK41309.1 - 1.5e-08 34.4 6.9 1.5e-08 34.4 6.9 2.7 3 0 0 3 3 3 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.21 CRK41309.1 - 2e-05 24.6 11.7 6.3e-05 23.0 11.7 1.8 1 1 0 1 1 1 1 bZIP transcription factor Mt_ATP-synt_D PF05873.12 CRK41309.1 - 0.0097 15.8 1.6 0.021 14.7 1.6 1.5 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) Atg14 PF10186.9 CRK41309.1 - 0.023 13.8 3.6 0.18 10.8 3.4 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fmp27_WPPW PF10359.9 CRK41309.1 - 0.043 12.7 6.4 0.092 11.6 6.4 1.5 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Cdh1_DBD_1 PF18196.1 CRK41309.1 - 0.072 13.4 3.5 0.15 12.4 3.5 1.5 1 0 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 dsrm PF00035.26 CRK41309.1 - 0.11 13.2 0.0 0.32 11.7 0.0 1.7 1 0 0 1 1 1 0 Double-stranded RNA binding motif HIP1_clath_bdg PF16515.5 CRK41309.1 - 0.8 10.3 15.6 0.12 13.0 7.6 2.4 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF3584 PF12128.8 CRK41309.1 - 1.1 6.6 10.1 1.8 6.0 10.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Aminotran_1_2 PF00155.21 CRK41310.1 - 1.4e-39 136.3 0.0 1.8e-39 136.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_3 PF00202.21 CRK41310.1 - 0.12 11.0 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-III DHR-2 PF06920.13 CRK41311.1 - 0.066 11.9 0.0 0.1 11.2 0.0 1.2 1 0 0 1 1 1 0 Dock homology region 2 GTP_cyclohydroI PF01227.22 CRK41312.1 - 8.3e-47 158.9 1.2 7.8e-26 90.6 0.0 2.2 1 1 1 2 2 2 2 GTP cyclohydrolase I TAFII28 PF04719.14 CRK41313.1 - 1.4e-29 102.0 0.0 2.5e-29 101.2 0.0 1.4 1 0 0 1 1 1 1 hTAFII28-like protein conserved region HsbA PF12296.8 CRK41314.1 - 3.2e-24 85.7 12.1 3.2e-24 85.7 12.1 2.1 1 1 1 2 2 2 2 Hydrophobic surface binding protein A OmpH PF03938.14 CRK41314.1 - 0.96 9.8 8.6 2.1 8.7 8.2 1.7 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Glyco_hydro_2_C PF02836.17 CRK41316.1 - 8.7e-103 343.6 0.0 1.3e-102 343.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 CRK41316.1 - 4.1e-68 229.6 0.0 9.6e-68 228.4 0.0 1.6 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 CRK41316.1 - 5.1e-46 156.7 0.1 1.4e-45 155.3 0.1 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain DUF4981 PF16353.5 CRK41316.1 - 1e-21 77.2 0.5 1.1e-20 73.9 0.1 2.8 2 0 0 2 2 2 1 Domain of unknown function(DUF4981) Glyco_hydro_2 PF00703.21 CRK41316.1 - 1.1e-15 58.2 1.1 2.3e-15 57.2 0.3 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 E1-E2_ATPase PF00122.20 CRK41317.1 - 4.6e-38 130.6 14.5 4.3e-32 111.1 0.0 3.5 3 1 1 4 4 4 2 E1-E2 ATPase Cation_ATPase PF13246.6 CRK41317.1 - 1.6e-29 101.8 0.0 9.7e-17 60.8 0.0 2.4 2 0 0 2 2 2 2 Cation transport ATPase (P-type) Cation_ATPase_C PF00689.21 CRK41317.1 - 5.1e-28 98.0 7.6 5.1e-28 98.0 7.6 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 CRK41317.1 - 3.3e-20 73.3 0.0 4.8e-15 56.4 0.0 2.8 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CRK41317.1 - 3.8e-14 52.1 0.0 8e-14 51.1 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CRK41317.1 - 0.00014 21.7 0.6 0.00028 20.7 0.2 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase MobC PF05713.11 CRK41317.1 - 0.0056 17.1 0.5 6.4 7.3 0.1 2.8 2 0 0 2 2 2 2 Bacterial mobilisation protein (MobC) Na_Pi_cotrans PF02690.15 CRK41317.1 - 0.01 16.0 3.5 0.01 16.0 3.5 2.2 2 0 0 2 2 2 0 Na+/Pi-cotransporter LRR_2 PF07723.13 CRK41317.1 - 0.097 13.4 0.0 43 5.0 0.0 3.0 2 0 0 2 2 2 0 Leucine Rich Repeat DUF2463 PF09591.10 CRK41317.1 - 0.11 12.4 0.7 0.23 11.3 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2463) zf-H2C2 PF09337.10 CRK41317.1 - 0.19 12.0 1.6 34 4.8 0.0 3.3 4 0 0 4 4 4 0 H2C2 zinc finger adh_short PF00106.25 CRK41318.1 - 7.9e-35 120.1 0.0 7.4e-26 90.8 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CRK41318.1 - 1.9e-22 80.0 0.0 2e-15 57.0 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK41318.1 - 1.1e-10 41.7 0.0 1.7e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 KR domain 4HBT_2 PF13279.6 CRK41318.1 - 6.3e-05 23.4 0.0 0.00011 22.6 0.0 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily Polysacc_synt_2 PF02719.15 CRK41318.1 - 0.01 15.0 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 CRK41318.1 - 0.03 13.8 0.0 0.11 11.9 0.0 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CRK41318.1 - 0.032 13.6 0.0 0.091 12.1 0.0 1.8 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase ECH_1 PF00378.20 CRK41319.1 - 2.2e-37 128.7 0.0 1.1e-17 64.1 0.0 2.5 2 1 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CRK41319.1 - 2e-24 86.7 0.1 3e-13 50.0 0.0 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase TOM13 PF08219.11 CRK41319.1 - 0.051 13.6 0.2 0.48 10.4 0.0 2.6 3 0 0 3 3 3 0 Outer membrane protein TOM13 Fungal_trans PF04082.18 CRK41320.1 - 2.8e-07 29.9 0.1 4.2e-07 29.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain UvdE PF03851.14 CRK41321.1 - 1.4e-110 368.9 0.0 2.1e-110 368.3 0.0 1.3 1 0 0 1 1 1 1 UV-endonuclease UvdE Peptidase_S64 PF08192.11 CRK41321.1 - 0.43 9.0 0.6 0.63 8.5 0.6 1.1 1 0 0 1 1 1 0 Peptidase family S64 Zn_clus PF00172.18 CRK41322.1 - 3e-09 36.9 9.1 5.6e-09 36.0 9.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 CRK41322.1 - 1.7e-05 24.0 1.5 9.3e-05 21.6 1.4 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Exo_endo_phos PF03372.23 CRK41323.1 - 1.4e-09 37.9 3.6 5.7e-09 35.8 3.6 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 CRK41323.1 - 0.059 13.2 0.2 0.69 9.8 0.0 2.4 3 0 0 3 3 3 0 Endonuclease-reverse transcriptase He_PIG PF05345.12 CRK41323.1 - 0.21 11.8 4.1 0.38 11.0 2.5 2.3 2 0 0 2 2 2 0 Putative Ig domain ATP-synt_I PF03899.15 CRK41324.1 - 0.0045 17.3 1.4 0.0073 16.7 1.4 1.4 1 0 0 1 1 1 1 ATP synthase I chain DHHC PF01529.20 CRK41324.1 - 0.0061 16.7 0.0 0.0093 16.1 0.0 1.4 1 1 0 1 1 1 1 DHHC palmitoyltransferase DHHC PF01529.20 CRK41326.1 - 7.5e-53 178.2 21.1 1.4e-28 99.6 6.0 3.1 4 0 0 4 4 4 2 DHHC palmitoyltransferase Imm17 PF15562.6 CRK41326.1 - 0.0088 15.9 0.3 7.5 6.5 0.0 2.8 2 0 0 2 2 2 2 Immunity protein 17 PSI PF01437.25 CRK41326.1 - 0.059 13.9 14.3 0.95 10.0 2.7 2.5 2 0 0 2 2 2 0 Plexin repeat Ferric_reduct PF01794.19 CRK41326.1 - 0.34 11.1 3.6 13 5.9 0.1 2.5 2 0 0 2 2 2 0 Ferric reductase like transmembrane component DUF2065 PF09838.9 CRK41326.1 - 2.4 8.2 8.5 6.6 6.8 1.2 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2065) ADH_N PF08240.12 CRK41326.1 - 3.3 7.6 6.2 19 5.2 0.5 2.5 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-like domain Pr_beta_C PF12465.8 CRK41327.1 - 0.55 9.7 2.5 22 4.6 0.2 2.4 2 0 0 2 2 2 0 Proteasome beta subunits C terminal HAD PF12710.7 CRK41328.1 - 1e-19 71.7 0.1 1.5e-19 71.1 0.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CRK41328.1 - 2.3e-16 60.7 1.0 3.8e-16 60.0 1.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CRK41328.1 - 1.8e-09 37.7 0.7 1.4e-08 34.9 0.1 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CRK41328.1 - 0.00074 19.6 0.5 0.58 10.2 0.0 2.7 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase DUF705 PF05152.12 CRK41328.1 - 0.023 14.2 0.0 0.034 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF705) Put_Phosphatase PF06888.12 CRK41328.1 - 0.053 12.9 0.1 3.7 6.9 0.0 2.3 2 0 0 2 2 2 0 Putative Phosphatase TIP39 PF14980.6 CRK41328.1 - 0.067 13.1 0.3 0.15 11.9 0.3 1.6 1 0 0 1 1 1 0 TIP39 peptide Hydrolase_3 PF08282.12 CRK41330.1 - 1.4e-09 38.0 1.4 1.2e-08 35.0 0.1 2.5 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CRK41330.1 - 2.2e-09 38.0 0.4 0.00034 21.1 0.0 2.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CRK41330.1 - 3e-09 37.5 5.4 2.2e-08 34.7 5.4 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CRK41330.1 - 0.0065 16.6 0.8 0.53 10.3 0.0 2.6 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase DUF705 PF05152.12 CRK41330.1 - 0.022 14.3 0.0 0.032 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF705) Put_Phosphatase PF06888.12 CRK41330.1 - 0.056 12.8 0.1 3.4 7.0 0.0 2.2 2 0 0 2 2 2 0 Putative Phosphatase TIP39 PF14980.6 CRK41330.1 - 0.064 13.1 0.3 0.14 12.0 0.3 1.5 1 0 0 1 1 1 0 TIP39 peptide PAPS_reduct PF01507.19 CRK41331.1 - 9.4e-42 143.0 0.1 2e-41 141.9 0.0 1.6 2 0 0 2 2 2 1 Phosphoadenosine phosphosulfate reductase family TYW3 PF02676.14 CRK41332.1 - 5.3e-73 244.9 0.0 7.1e-73 244.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase TYW3 DUF1690 PF07956.11 CRK41334.1 - 1.7e-42 145.1 4.3 2e-42 144.9 4.3 1.0 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) FUSC PF04632.12 CRK41334.1 - 0.13 10.7 5.3 0.15 10.6 5.3 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Ferric_reduct PF01794.19 CRK41336.1 - 1.7e-23 83.1 10.1 4.5e-23 81.7 10.1 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 CRK41336.1 - 1.1e-16 61.3 0.0 5.2e-14 52.6 0.0 2.3 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 CRK41336.1 - 3.9e-08 33.3 0.0 4.9e-06 26.6 0.0 2.6 2 0 0 2 2 2 2 FAD-binding domain HEAT PF02985.22 CRK41338.1 - 2.1e-19 68.0 8.2 0.0005 20.1 0.0 11.6 13 0 0 13 13 10 2 HEAT repeat IBN_N PF03810.19 CRK41338.1 - 2.3e-14 53.1 12.7 3.7e-08 33.2 0.9 6.0 6 0 0 6 6 6 2 Importin-beta N-terminal domain HEAT_EZ PF13513.6 CRK41338.1 - 2.1e-12 47.3 7.7 2.2e-08 34.4 0.0 7.1 7 1 0 7 7 7 2 HEAT-like repeat HEAT_2 PF13646.6 CRK41338.1 - 1e-09 38.6 19.2 0.00019 21.7 0.2 9.0 4 2 6 10 10 10 2 HEAT repeats Arm PF00514.23 CRK41338.1 - 0.00053 19.9 4.6 23 5.2 0.0 6.8 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat DUF1778 PF08681.11 CRK41338.1 - 0.0015 18.4 2.3 2.6 8.0 0.1 3.5 3 0 0 3 3 3 2 Protein of unknown function (DUF1778) FliC_SP PF12613.8 CRK41338.1 - 0.0033 17.9 14.1 0.49 10.9 3.2 3.2 2 0 0 2 2 2 2 Flagellin structural protein DUF3347 PF11827.8 CRK41338.1 - 0.0035 17.5 11.3 0.34 11.1 1.7 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3347) CLASP_N PF12348.8 CRK41338.1 - 0.0072 15.9 6.9 3.9 7.0 0.0 4.9 4 2 0 5 5 5 2 CLASP N terminal Cnd1 PF12717.7 CRK41338.1 - 0.092 12.8 5.1 0.21 11.6 0.0 3.9 5 1 1 6 6 6 0 non-SMC mitotic condensation complex subunit 1 Morc6_S5 PF17942.1 CRK41338.1 - 0.12 12.4 0.0 1.3 9.1 0.0 2.2 2 0 0 2 2 2 0 Morc6 ribosomal protein S5 domain 2-like DUF1548 PF07579.11 CRK41338.1 - 0.31 11.4 2.8 30 4.9 0.0 3.3 4 0 0 4 4 4 0 Domain of Unknown Function (DUF1548) DUF2163 PF09931.9 CRK41338.1 - 0.89 9.7 3.7 33 4.6 0.1 3.1 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2163) DUF2887 PF11103.8 CRK41338.1 - 1.1 9.2 3.4 32 4.4 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2887) HEAT PF02985.22 CRK41340.1 - 2e-13 49.3 13.2 0.00028 20.9 0.0 7.7 10 0 0 10 10 10 2 HEAT repeat HEAT_EZ PF13513.6 CRK41340.1 - 3.8e-13 49.6 5.7 1.2e-08 35.2 0.0 5.6 6 0 0 6 6 6 2 HEAT-like repeat HEAT_2 PF13646.6 CRK41340.1 - 1.9e-09 37.8 2.7 9.4e-05 22.7 0.2 5.6 4 1 2 6 6 6 3 HEAT repeats MMS19_C PF12460.8 CRK41340.1 - 4.1e-06 26.2 0.7 0.00035 19.8 0.3 2.4 1 1 2 3 3 3 1 RNAPII transcription regulator C-terminal CLASP_N PF12348.8 CRK41340.1 - 0.00011 21.8 0.8 2.4 7.7 0.0 4.0 2 2 2 4 4 4 2 CLASP N terminal Arm PF00514.23 CRK41340.1 - 0.0019 18.2 3.8 13 6.0 0.0 5.1 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat DUF3385 PF11865.8 CRK41340.1 - 0.0028 17.6 0.4 6.2 6.7 0.2 4.2 3 1 0 3 3 3 1 Domain of unknown function (DUF3385) Cnd1 PF12717.7 CRK41340.1 - 0.0034 17.5 0.3 0.097 12.7 0.0 3.2 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 RIX1 PF08167.12 CRK41340.1 - 0.0071 16.1 0.1 1.7 8.4 0.0 3.4 1 1 2 3 3 3 1 rRNA processing/ribosome biogenesis Tti2 PF10521.9 CRK41340.1 - 0.01 15.4 0.1 11 5.4 0.0 3.7 4 1 0 4 4 4 0 Tti2 family Fungal_trans PF04082.18 CRK41343.1 - 2.8e-13 49.5 0.5 5e-13 48.7 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain TFIIA PF03153.13 CRK41343.1 - 1.8 8.5 29.6 3.1 7.7 29.6 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit p450 PF00067.22 CRK41346.1 - 2e-63 214.8 0.0 2.5e-63 214.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 CRK41348.1 - 6.9e-06 25.3 0.1 1e-05 24.7 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK41348.1 - 9.6e-05 22.4 7.5 9.6e-05 22.4 7.5 2.4 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.6 CRK41348.1 - 0.00025 21.6 12.0 0.0058 17.4 1.4 3.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CRK41348.1 - 0.00043 20.6 10.7 0.0029 17.9 1.9 3.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 CRK41348.1 - 0.0019 18.5 2.5 0.0019 18.5 2.5 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 CRK41348.1 - 0.024 14.6 1.8 0.024 14.6 1.8 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CRK41348.1 - 0.4 11.0 5.3 0.33 11.3 0.4 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 CRK41348.1 - 0.83 10.0 7.4 0.83 10.0 1.2 2.6 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.10 CRK41348.1 - 3 8.0 5.9 11 6.2 2.2 2.8 2 0 0 2 2 2 0 Zinc ribbon domain p450 PF00067.22 CRK41350.1 - 4.9e-36 124.5 0.0 5.3e-36 124.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 CRK41352.1 - 0.032 13.3 0.0 0.038 13.0 0.0 1.1 1 0 0 1 1 1 0 Fungal specific transcription factor domain p450 PF00067.22 CRK41354.1 - 4.9e-72 243.2 0.0 6e-72 242.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_L27 PF01016.19 CRK41356.1 - 2.9e-26 91.3 0.0 6.8e-26 90.1 0.0 1.7 1 0 0 1 1 1 1 Ribosomal L27 protein IPP-2 PF04979.14 CRK41356.1 - 3.1e-23 83.0 8.5 3.1e-23 83.0 8.5 5.0 5 1 0 5 5 5 1 Protein phosphatase inhibitor 2 (IPP-2) DUF3716 PF12511.8 CRK41356.1 - 0.016 15.2 1.5 0.031 14.3 1.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) CENP-C_C PF11699.8 CRK41356.1 - 0.14 12.4 0.0 0.33 11.2 0.0 1.7 1 0 0 1 1 1 0 Mif2/CENP-C like NOA36 PF06524.12 CRK41356.1 - 1.3 8.3 14.8 5.5 6.2 14.8 2.0 1 0 0 1 1 1 0 NOA36 protein Aldolase_II PF00596.21 CRK41360.1 - 3.8e-49 167.2 0.1 4.9e-49 166.8 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain SET PF00856.28 CRK41362.1 - 7.5e-12 46.0 0.0 1.7e-11 44.8 0.0 1.6 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 CRK41362.1 - 7.3e-10 39.6 0.9 1.7e-09 38.5 0.6 1.7 1 1 0 1 1 1 1 Rubisco LSMT substrate-binding Apt1 PF10351.9 CRK41362.1 - 0.031 13.1 0.0 0.046 12.6 0.0 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Xrn1_D3 PF18194.1 CRK41362.1 - 2.6 8.2 4.3 78 3.5 0.0 3.5 4 0 0 4 4 4 0 Exoribonuclease 1 Domain-3 Adap_comp_sub PF00928.21 CRK41364.1 - 3.2e-90 302.1 0.0 5.8e-90 301.2 0.0 1.4 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CRK41364.1 - 4.8e-09 36.3 0.2 7.7e-09 35.6 0.2 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF1752 PF08550.10 CRK41370.1 - 2.1e-05 24.2 0.9 4.2e-05 23.3 0.9 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) adh_short_C2 PF13561.6 CRK41372.1 - 2.2e-51 174.7 0.0 2.9e-51 174.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRK41372.1 - 3.1e-35 121.4 0.0 4.6e-35 120.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CRK41372.1 - 1.9e-09 37.7 0.1 3.3e-09 36.9 0.1 1.3 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 CRK41372.1 - 0.05 13.0 0.1 0.45 9.9 0.1 2.0 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase HypA PF01155.19 CRK41375.1 - 0.072 13.1 0.3 0.072 13.1 0.3 3.4 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Phage_GPO PF05929.11 CRK41375.1 - 0.1 12.2 5.5 0.15 11.7 5.5 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF4650 PF15509.6 CRK41375.1 - 0.83 8.9 6.0 1.3 8.3 6.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4650) FYVE_2 PF02318.16 CRK41375.1 - 4.1 7.7 17.4 1.3 9.2 0.5 3.4 3 1 0 3 3 3 0 FYVE-type zinc finger Ndc1_Nup PF09531.10 CRK41375.1 - 6.2 5.4 5.5 6.5 5.3 5.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup F-box-like PF12937.7 CRK41377.1 - 2.3e-08 33.8 0.1 5e-08 32.7 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CRK41377.1 - 8.5e-08 31.9 0.0 2.8e-07 30.2 0.0 1.9 2 0 0 2 2 2 1 F-box domain UIM PF02809.20 CRK41377.1 - 0.11 12.4 13.1 0.021 14.7 6.0 2.7 2 0 0 2 2 2 0 Ubiquitin interaction motif Asp PF00026.23 CRK41381.1 - 5.3e-13 49.1 0.8 3e-12 46.6 0.8 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CRK41381.1 - 0.73 10.0 4.9 1.3 9.3 0.0 3.3 4 0 0 4 4 4 0 Xylanase inhibitor N-terminal FAD_binding_1 PF00667.20 CRK41383.1 - 2.3e-30 105.8 0.0 3.6e-30 105.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 CRK41383.1 - 1.8e-07 31.7 0.1 4.6e-06 27.2 0.0 2.7 2 1 1 3 3 3 1 Oxidoreductase NAD-binding domain Flavodoxin_1 PF00258.25 CRK41383.1 - 5.3e-06 26.7 0.4 0.0025 18.0 0.0 2.9 2 1 1 3 3 3 2 Flavodoxin RRM_1 PF00076.22 CRK41385.1 - 1.6e-31 107.9 0.1 5.3e-15 55.0 0.0 3.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CRK41385.1 - 6e-05 23.1 0.0 0.037 14.1 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 CRK41385.1 - 0.0012 18.4 0.0 1.1 8.8 0.0 3.2 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 CRK41385.1 - 0.029 14.6 0.0 4.9 7.4 0.0 3.1 3 0 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter DUF4783 PF16022.5 CRK41385.1 - 0.12 12.6 0.0 1.2 9.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4783) Limkain-b1 PF11608.8 CRK41385.1 - 0.12 12.5 0.2 26 4.9 0.0 2.8 3 0 0 3 3 3 0 Limkain b1 DbpA PF03880.15 CRK41385.1 - 0.12 12.3 0.3 11 6.2 0.0 2.7 3 0 0 3 3 3 0 DbpA RNA binding domain DUF4944 PF16302.5 CRK41385.1 - 0.19 11.8 0.0 19 5.3 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4944) FXMRP1_C_core PF12235.8 CRK41385.1 - 1.8 9.2 13.0 0.75 10.4 9.0 2.2 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal CUE PF02845.16 CRK41390.1 - 8.3e-11 41.4 0.0 1.5e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 CUE domain SKG6 PF08693.10 CRK41395.1 - 4.1e-10 38.9 5.2 8.8e-10 37.8 5.2 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain CD34_antigen PF06365.12 CRK41395.1 - 0.009 15.6 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 CD34/Podocalyxin family Arb2 PF09757.9 CRK41397.1 - 4.5e-101 337.3 0.0 6.5e-101 336.8 0.0 1.2 1 0 0 1 1 1 1 Arb2 domain Hist_deacetyl PF00850.19 CRK41397.1 - 1.8e-79 267.4 0.0 2.6e-79 266.9 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain adh_short PF00106.25 CRK41397.1 - 2.1e-33 115.4 0.4 3.8e-33 114.6 0.4 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK41397.1 - 2.7e-23 82.8 0.2 5.2e-23 81.8 0.2 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK41397.1 - 1.5e-07 31.5 0.5 2.6e-07 30.7 0.5 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 CRK41397.1 - 0.023 14.6 0.1 0.047 13.6 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H-binding Epimerase PF01370.21 CRK41397.1 - 0.043 13.3 0.2 0.075 12.5 0.2 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CRK41397.1 - 0.056 12.4 0.1 0.085 11.8 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 CRK41397.1 - 0.18 11.1 0.1 0.33 10.3 0.1 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase ADH_zinc_N PF00107.26 CRK41397.1 - 0.2 11.6 0.2 0.37 10.8 0.2 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase F-box_4 PF15966.5 CRK41400.1 - 0.16 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 F-box F-box-like PF12937.7 CRK41400.1 - 0.17 11.8 2.3 0.25 11.3 0.0 2.4 3 0 0 3 3 3 0 F-box-like Brix PF04427.18 CRK41402.1 - 1.1e-38 133.3 0.0 1.6e-38 132.8 0.0 1.1 1 0 0 1 1 1 1 Brix domain Chromo PF00385.24 CRK41405.1 - 5.6e-14 51.8 15.1 6.3e-07 29.2 3.2 2.5 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain DUF5607 PF18355.1 CRK41405.1 - 0.071 13.6 1.3 22 5.6 0.0 3.0 4 0 0 4 4 4 0 Domain of unknown function (DUF5607) P16-Arc PF04699.14 CRK41405.1 - 0.13 12.7 1.2 28 5.2 0.1 3.1 2 0 0 2 2 2 0 ARP2/3 complex 16 kDa subunit (p16-Arc) Pex14_N PF04695.13 CRK41406.1 - 1.3e-36 126.7 2.6 1.3e-36 126.7 2.6 2.4 2 1 1 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Shisa PF13908.6 CRK41406.1 - 4.6 7.4 4.7 1.1 9.4 0.7 1.9 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator PAPA-1 PF04795.12 CRK41409.1 - 1.6e-26 92.9 7.0 1.6e-26 92.9 7.0 4.5 4 2 2 6 6 6 1 PAPA-1-like conserved region Vps51 PF08700.11 CRK41410.1 - 1.5e-28 98.7 0.0 3.3e-28 97.6 0.0 1.6 1 0 0 1 1 1 1 Vps51/Vps67 COG5 PF10392.9 CRK41410.1 - 0.0011 19.2 0.1 0.0064 16.7 0.1 2.1 1 1 0 1 1 1 1 Golgi transport complex subunit 5 Dor1 PF04124.12 CRK41410.1 - 0.022 13.5 0.0 0.025 13.3 0.0 1.1 1 0 0 1 1 1 0 Dor1-like family NmrA PF05368.13 CRK41412.1 - 1.9e-22 80.0 0.0 2.4e-22 79.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 CRK41412.1 - 6e-07 29.5 0.0 9.9e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 CRK41412.1 - 0.12 12.3 0.1 0.22 11.4 0.1 1.4 1 0 0 1 1 1 0 KR domain RMI1_N PF08585.12 CRK41414.1 - 1.8e-57 194.6 0.0 2e-57 194.4 0.0 1.0 1 0 0 1 1 1 1 RecQ mediated genome instability protein TPR_16 PF13432.6 CRK41415.1 - 3.7e-34 117.1 48.2 3.1e-07 30.9 1.8 12.9 10 2 2 12 12 12 6 Tetratricopeptide repeat TPR_19 PF14559.6 CRK41415.1 - 9.6e-30 102.9 32.3 0.00036 21.0 0.3 11.1 8 3 2 10 10 10 8 Tetratricopeptide repeat TPR_2 PF07719.17 CRK41415.1 - 1.7e-29 99.5 46.0 0.022 14.9 0.0 16.0 18 0 0 18 18 16 10 Tetratricopeptide repeat TPR_1 PF00515.28 CRK41415.1 - 7e-28 95.3 33.4 0.00027 20.6 0.0 14.7 15 0 0 15 15 14 7 Tetratricopeptide repeat TPR_12 PF13424.6 CRK41415.1 - 1.2e-26 92.8 38.5 0.0061 16.8 0.1 14.1 12 2 1 13 13 13 8 Tetratricopeptide repeat TPR_14 PF13428.6 CRK41415.1 - 2.1e-24 84.1 44.9 0.0086 16.8 1.5 17.3 13 6 4 17 17 15 5 Tetratricopeptide repeat TPR_17 PF13431.6 CRK41415.1 - 3.5e-24 83.4 15.3 1.1 9.8 0.0 16.2 17 0 0 17 17 16 1 Tetratricopeptide repeat TPR_8 PF13181.6 CRK41415.1 - 1e-21 75.3 38.0 0.0046 17.1 0.0 14.9 16 0 0 16 16 13 7 Tetratricopeptide repeat Ank_2 PF12796.7 CRK41415.1 - 1.1e-19 70.8 0.4 5.8e-12 46.0 0.0 4.1 3 1 1 4 4 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 CRK41415.1 - 3e-14 52.7 6.0 0.00053 20.3 0.0 6.1 6 0 0 6 6 5 4 Ankyrin repeat Ank_5 PF13857.6 CRK41415.1 - 3.9e-14 52.5 2.6 1.7e-06 28.2 0.0 4.4 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 CRK41415.1 - 1.4e-13 51.1 0.3 1.1e-05 25.9 0.0 5.2 3 1 1 4 4 4 2 Ankyrin repeats (many copies) TPR_7 PF13176.6 CRK41415.1 - 5.4e-12 44.9 34.2 0.0095 15.9 0.0 14.0 14 1 1 15 15 13 3 Tetratricopeptide repeat TPR_11 PF13414.6 CRK41415.1 - 2.1e-11 43.3 30.4 0.031 14.0 0.0 11.3 14 0 0 14 14 12 4 TPR repeat Ank_3 PF13606.6 CRK41415.1 - 1.4e-09 37.4 0.2 4.9e-06 26.5 0.0 3.7 3 0 0 3 3 2 1 Ankyrin repeat TPR_9 PF13371.6 CRK41415.1 - 1.2e-07 31.8 12.2 0.29 11.3 0.1 6.8 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 CRK41415.1 - 1.5e-05 25.3 40.4 0.34 11.6 0.0 15.3 20 0 0 20 20 12 1 Tetratricopeptide repeat TPR_MalT PF17874.1 CRK41415.1 - 0.00013 21.5 17.5 0.00051 19.5 0.3 6.0 5 1 0 5 5 5 1 MalT-like TPR region TPR_22 PF18833.1 CRK41415.1 - 0.0002 21.4 0.0 0.00079 19.5 0.0 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CRK41415.1 - 0.00035 20.8 18.3 3.6 7.9 0.0 8.1 8 0 0 8 8 7 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 CRK41415.1 - 0.00045 20.0 28.7 1.4 8.9 0.1 11.0 12 0 0 12 12 10 2 Tetratricopeptide repeat ChAPs PF09295.10 CRK41415.1 - 0.027 13.5 2.3 24 3.8 0.0 3.9 4 0 0 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) Helo_like_N PF17111.5 CRK41415.1 - 0.032 13.6 0.1 0.099 12.0 0.1 1.8 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins Fis1_TPR_C PF14853.6 CRK41415.1 - 0.043 13.9 0.6 12 6.1 0.0 5.3 5 1 1 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat DUF3517 PF12030.8 CRK41415.1 - 0.059 12.3 0.0 0.14 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3517) FliD_C PF07195.12 CRK41415.1 - 0.061 12.7 0.1 0.15 11.4 0.1 1.6 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus TPR_20 PF14561.6 CRK41415.1 - 0.075 13.4 19.5 4.5 7.7 0.2 7.1 6 1 0 6 6 6 0 Tetratricopeptide repeat DUF4919 PF16266.5 CRK41415.1 - 0.21 11.5 1.0 3.1 7.7 0.6 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4919) SesA PF17107.5 CRK41415.1 - 1.8 8.8 5.0 1.1 9.5 0.1 3.3 3 1 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Sugar_tr PF00083.24 CRK41417.1 - 1.6e-56 192.1 22.1 2.6e-40 138.7 1.3 2.1 1 1 0 2 2 2 2 Sugar (and other) transporter Pkinase PF00069.25 CRK41417.1 - 1.2e-17 64.2 0.0 1e-14 54.6 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Glyco_hydro_5_C PF18564.1 CRK41417.1 - 9.1e-16 58.2 0.0 2.3e-15 56.9 0.0 1.7 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Pkinase_Tyr PF07714.17 CRK41417.1 - 8.8e-12 44.8 0.1 5.8e-11 42.2 0.0 2.0 1 1 1 2 2 2 1 Protein tyrosine kinase Cellulase PF00150.18 CRK41417.1 - 1.9e-11 43.9 1.6 1.2e-07 31.5 0.1 2.5 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) MFS_1 PF07690.16 CRK41417.1 - 1.9e-08 33.7 58.3 7.5e-08 31.7 39.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_47 PF01532.20 CRK41420.1 - 2e-150 501.7 0.0 3e-148 494.5 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 Fig1 PF12351.8 CRK41422.1 - 1.5e-56 191.3 2.5 1.5e-56 191.3 2.5 3.0 3 0 0 3 3 3 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.12 CRK41422.1 - 1.1e-07 31.7 7.1 1.1e-07 31.7 7.1 1.9 2 0 0 2 2 2 1 SUR7/PalI family CorA PF01544.18 CRK41422.1 - 6.9e-06 25.6 0.6 6.9e-06 25.6 0.6 2.7 3 1 0 3 3 3 1 CorA-like Mg2+ transporter protein DUF898 PF05987.13 CRK41422.1 - 0.0012 17.9 7.7 0.0012 17.9 7.7 2.4 2 1 0 2 2 2 1 Bacterial protein of unknown function (DUF898) RINT1_TIP1 PF04437.13 CRK41427.1 - 1.3e-226 753.3 0.0 2.8e-179 597.2 0.0 2.5 2 0 0 2 2 2 2 RINT-1 / TIP-1 family DHR10 PF18595.1 CRK41427.1 - 0.00019 21.5 16.5 0.075 13.1 4.3 2.8 2 0 0 2 2 2 2 Designed helical repeat protein 10 domain Trimer_CC PF08954.11 CRK41427.1 - 0.00032 20.2 0.5 1.4 8.5 0.1 3.0 2 0 0 2 2 2 2 Trimerisation motif Glyco_hydro38C2 PF17677.1 CRK41427.1 - 0.0045 17.1 0.0 7.3 6.8 0.0 3.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Gtr1_RagA PF04670.12 CRK41427.1 - 0.0058 16.0 0.4 2.4 7.4 0.1 2.5 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region DUF4164 PF13747.6 CRK41427.1 - 0.012 15.9 29.4 0.36 11.1 4.9 5.7 3 1 1 5 5 5 0 Domain of unknown function (DUF4164) Pox_G5 PF04599.12 CRK41427.1 - 0.034 13.2 5.8 2.7 6.9 0.0 3.5 4 0 0 4 4 4 0 Poxvirus G5 protein DNA_ligase_aden PF01653.18 CRK41427.1 - 0.057 12.5 0.4 9.6 5.2 0.0 2.4 2 0 0 2 2 2 0 NAD-dependent DNA ligase adenylation domain Phage_GP20 PF06810.11 CRK41427.1 - 0.25 11.1 12.6 2 8.2 2.2 2.8 2 0 0 2 2 2 0 Phage minor structural protein GP20 DUF2730 PF10805.8 CRK41427.1 - 0.28 11.3 10.1 3.3 7.9 0.4 3.7 4 1 0 4 4 2 0 Protein of unknown function (DUF2730) TPR_MLP1_2 PF07926.12 CRK41427.1 - 0.3 11.2 23.4 0.31 11.1 3.9 3.5 4 0 0 4 4 4 0 TPR/MLP1/MLP2-like protein DUF2524 PF10732.9 CRK41427.1 - 0.68 10.3 8.9 7.8 6.9 1.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2524) COG2 PF06148.11 CRK41427.1 - 0.98 9.5 18.4 22 5.2 1.3 5.1 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 RasGAP_C PF03836.15 CRK41427.1 - 1.1 9.5 12.1 6.9 6.8 2.4 2.6 1 1 1 2 2 2 0 RasGAP C-terminus T3SS_needle_E PF08988.10 CRK41427.1 - 1.3 9.2 23.4 0.25 11.5 2.1 4.2 5 0 0 5 5 2 0 Type III secretion system, cytoplasmic E component of needle FlxA PF14282.6 CRK41427.1 - 1.8 8.6 15.8 7.1 6.7 4.0 2.8 2 0 0 2 2 2 0 FlxA-like protein Spc24 PF08286.11 CRK41427.1 - 2 8.7 12.7 7 7.0 3.0 2.9 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 FlaC_arch PF05377.11 CRK41427.1 - 2.5 8.6 4.3 57 4.2 0.3 3.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Endotoxin_C2 PF18449.1 CRK41427.1 - 3.3 8.1 9.1 22 5.5 1.3 3.2 2 0 0 2 2 2 0 Delta endotoxin Syntaxin-6_N PF09177.11 CRK41427.1 - 3.4 8.3 15.7 6.2 7.4 2.6 3.7 2 1 1 3 3 3 0 Syntaxin 6, N-terminal DUF826 PF05696.11 CRK41427.1 - 4.2 7.5 8.9 22 5.2 0.1 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF826) 5_nucleotid PF05761.14 CRK41427.1 - 4.7 6.0 6.0 34 3.2 0.8 3.0 2 1 1 3 3 3 0 5' nucleotidase family Cep57_MT_bd PF06657.13 CRK41427.1 - 4.8 7.7 11.8 16 6.0 2.2 3.2 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Cortex-I_coil PF09304.10 CRK41427.1 - 5.2 7.3 12.8 21 5.4 2.5 3.6 3 1 1 4 4 3 0 Cortexillin I, coiled coil Mito_carr PF00153.27 CRK41429.1 - 2.6e-56 187.5 0.8 6.2e-21 74.1 0.0 3.6 3 0 0 3 3 3 3 Mitochondrial carrier protein Sec34 PF04136.15 CRK41429.1 - 3.5e-48 163.3 1.5 6.5e-48 162.4 1.5 1.5 1 0 0 1 1 1 1 Sec34-like family SKA2 PF16740.5 CRK41429.1 - 0.41 10.5 3.6 3.5 7.5 0.1 3.2 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 CENP-F_leu_zip PF10473.9 CRK41429.1 - 2.3 8.2 7.6 0.23 11.5 1.7 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 RCC1 PF00415.18 CRK41431.1 - 6e-31 106.8 9.9 3.8e-10 40.2 0.0 7.8 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CRK41431.1 - 3.8e-16 58.4 28.4 5.3e-10 38.8 0.0 7.8 8 1 0 8 8 8 4 Regulator of chromosome condensation (RCC1) repeat RINT1_TIP1 PF04437.13 CRK41433.1 - 1.7e-79 268.0 0.0 2.3e-79 267.6 0.0 1.1 1 0 0 1 1 1 1 RINT-1 / TIP-1 family Y_phosphatase PF00102.27 CRK41433.1 - 2.2e-31 109.3 0.0 2.3e-16 60.1 0.0 2.2 2 0 0 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.20 CRK41433.1 - 0.0069 16.2 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 CRK41433.1 - 0.024 14.7 0.0 0.058 13.5 0.0 1.6 1 0 0 1 1 1 0 Inositol hexakisphosphate DUF3235 PF11574.8 CRK41433.1 - 5.6 7.9 6.8 1.2 10.0 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3235) Mito_carr PF00153.27 CRK41435.1 - 5.1e-59 196.2 2.0 3.7e-22 78.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Sec34 PF04136.15 CRK41437.1 - 1.1e-47 161.6 1.6 2.2e-47 160.7 1.6 1.5 1 0 0 1 1 1 1 Sec34-like family SKA2 PF16740.5 CRK41437.1 - 0.025 14.3 3.4 0.43 10.4 0.1 3.4 4 0 0 4 4 4 0 Spindle and kinetochore-associated protein 2 Y_phosphatase PF00102.27 CRK41440.1 - 1.6e-39 135.9 0.0 7.5e-20 71.5 0.0 2.1 2 0 0 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.20 CRK41440.1 - 0.0045 16.8 0.0 0.0082 16.0 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 CRK41440.1 - 0.063 13.4 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 CRK41440.1 - 0.12 12.3 0.0 0.32 10.9 0.0 1.7 2 0 0 2 2 2 0 Tyrosine phosphatase family Pinin_SDK_N PF04697.13 CRK41440.1 - 1.2 9.8 9.3 4.9 7.8 0.9 2.5 1 1 1 2 2 2 0 pinin/SDK conserved region Folliculin PF11704.8 CRK41448.1 - 2.5e-60 203.5 2.1 3.7e-59 199.7 0.0 2.7 2 1 0 2 2 2 1 Vesicle coat protein involved in Golgi to plasma membrane transport AAA PF00004.29 CRK41449.1 - 2.2e-45 154.3 0.5 7.7e-45 152.6 0.0 2.1 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 CRK41449.1 - 1.3e-10 41.0 0.1 7.6e-10 38.6 0.0 2.2 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 CRK41449.1 - 2.2e-08 34.2 0.7 6.6e-08 32.6 0.1 2.2 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CRK41449.1 - 5.4e-08 33.1 0.0 1.1e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 CRK41449.1 - 3e-07 31.0 0.7 3.7e-05 24.2 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 CRK41449.1 - 4.4e-06 26.1 0.0 9.3e-06 25.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 CRK41449.1 - 3.2e-05 24.2 0.9 0.0088 16.3 0.1 2.7 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 CRK41449.1 - 0.00024 20.9 0.0 0.00073 19.3 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_3 PF17862.1 CRK41449.1 - 0.00036 20.3 0.0 0.00086 19.1 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_18 PF13238.6 CRK41449.1 - 0.00048 20.7 0.0 0.0013 19.3 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_28 PF13521.6 CRK41449.1 - 0.00064 20.0 0.0 0.0014 18.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 CRK41449.1 - 0.00089 18.8 0.1 0.0032 17.0 0.1 1.8 1 1 0 1 1 1 1 P-loop containing dynein motor region TIP49 PF06068.13 CRK41449.1 - 0.0014 17.9 0.0 0.0026 17.1 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain TsaE PF02367.17 CRK41449.1 - 0.0014 18.6 0.0 0.019 15.0 0.0 2.2 1 1 1 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 CRK41449.1 - 0.002 18.1 0.1 0.0078 16.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CRK41449.1 - 0.0021 18.4 0.0 0.0046 17.3 0.0 1.6 1 0 0 1 1 1 1 RNA helicase NTPase_1 PF03266.15 CRK41449.1 - 0.0044 17.0 0.0 0.015 15.2 0.0 1.9 2 0 0 2 2 2 1 NTPase NACHT PF05729.12 CRK41449.1 - 0.005 16.8 0.5 0.11 12.4 0.0 2.9 2 1 1 3 3 3 1 NACHT domain AAA_3 PF07726.11 CRK41449.1 - 0.0058 16.5 0.0 0.018 14.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 CRK41449.1 - 0.0062 16.3 1.3 0.013 15.2 0.1 2.2 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 CRK41449.1 - 0.0071 15.8 0.2 0.016 14.6 0.1 1.7 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 CRK41449.1 - 0.008 16.3 0.0 0.019 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 CRK41449.1 - 0.013 15.2 0.1 0.031 14.0 0.0 1.8 2 0 0 2 2 1 0 IstB-like ATP binding protein TniB PF05621.11 CRK41449.1 - 0.013 14.9 0.0 0.5 9.7 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein AAA_24 PF13479.6 CRK41449.1 - 0.022 14.5 0.2 0.055 13.2 0.2 1.8 1 1 0 1 1 1 0 AAA domain Viral_Hsp90 PF03225.14 CRK41449.1 - 0.034 12.7 0.0 0.053 12.0 0.0 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue Bac_DnaA PF00308.18 CRK41449.1 - 0.04 13.7 0.0 0.077 12.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein ATPase PF06745.13 CRK41449.1 - 0.04 13.3 1.2 0.56 9.5 0.0 2.5 3 0 0 3 3 3 0 KaiC AAA_11 PF13086.6 CRK41449.1 - 0.043 13.6 0.1 0.14 12.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 CRK41449.1 - 0.045 13.7 1.0 0.34 10.8 0.0 2.5 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea AFG1_ATPase PF03969.16 CRK41449.1 - 0.052 12.4 0.1 0.14 11.1 0.0 1.7 2 0 0 2 2 2 0 AFG1-like ATPase AAA_25 PF13481.6 CRK41449.1 - 0.066 12.8 1.1 0.19 11.2 0.3 2.2 2 1 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 CRK41449.1 - 0.069 12.9 0.2 1.3 8.7 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 CRK41449.1 - 0.088 12.1 0.1 0.22 10.8 0.0 1.7 2 0 0 2 2 1 0 Zeta toxin AAA_23 PF13476.6 CRK41449.1 - 0.094 13.2 0.4 7 7.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 CRK41449.1 - 0.13 12.6 0.1 0.37 11.1 0.1 1.7 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 CRK41449.1 - 0.14 11.7 0.0 0.34 10.5 0.0 1.6 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SPACA9 PF15120.6 CRK41449.1 - 0.15 11.8 1.0 14 5.4 0.0 2.2 2 0 0 2 2 2 0 Sperm acrosome-associated protein 9 AAA_29 PF13555.6 CRK41449.1 - 0.16 11.7 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Parvo_NS1 PF01057.17 CRK41449.1 - 0.21 10.7 0.0 0.37 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Mis14 PF08641.12 CRK41452.1 - 1.2e-16 61.3 3.6 1.2e-16 61.3 3.6 1.5 2 0 0 2 2 2 1 Kinetochore protein Mis14 like SWIRM-assoc_3 PF16498.5 CRK41452.1 - 0.012 15.8 0.1 1.9 8.8 0.0 2.5 2 0 0 2 2 2 0 SWIRM-associated domain at the C-terminal SOGA PF11365.8 CRK41452.1 - 0.013 16.6 2.3 0.029 15.5 2.3 1.5 1 0 0 1 1 1 0 Protein SOGA Med8 PF10232.9 CRK41452.1 - 0.12 12.0 4.9 0.2 11.2 4.9 1.3 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 CRAL_TRIO PF00650.20 CRK41454.1 - 9.3e-36 122.9 0.0 1.8e-35 122.0 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain Prefoldin PF02996.17 CRK41454.1 - 5e-29 100.7 1.8 6.1e-29 100.4 0.7 1.7 2 0 0 2 2 2 1 Prefoldin subunit CRAL_TRIO_N PF03765.15 CRK41454.1 - 6.5e-08 32.6 0.7 2.1e-07 31.0 0.1 2.2 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 CRK41454.1 - 0.006 16.7 0.0 0.07 13.3 0.0 2.2 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain iPGM_N PF06415.13 CRK41456.1 - 7.2e-76 254.4 0.0 1.8e-75 253.1 0.0 1.7 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.18 CRK41456.1 - 2.1e-60 204.1 0.0 6.7e-60 202.5 0.0 1.9 1 1 0 1 1 1 1 Metalloenzyme superfamily NACHT_N PF17100.5 CRK41456.1 - 3.4e-51 174.2 0.7 7.3e-51 173.1 0.7 1.5 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase Sulfatase PF00884.23 CRK41456.1 - 0.00023 20.7 0.0 0.00041 19.8 0.0 1.4 1 0 0 1 1 1 1 Sulfatase DUF1877 PF08974.10 CRK41456.1 - 0.014 15.5 1.2 0.96 9.5 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1877) Med9 PF07544.13 CRK41458.1 - 6.6e-17 61.4 2.2 1e-16 60.7 2.2 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Phage_GP20 PF06810.11 CRK41458.1 - 0.0012 18.6 1.8 0.002 17.9 1.8 1.3 1 0 0 1 1 1 1 Phage minor structural protein GP20 NPV_P10 PF05531.12 CRK41458.1 - 0.0014 19.0 0.5 0.01 16.3 0.2 2.0 2 0 0 2 2 2 1 Nucleopolyhedrovirus P10 protein UPF0242 PF06785.11 CRK41458.1 - 0.0042 17.2 0.1 0.0043 17.2 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Spectrin PF00435.21 CRK41458.1 - 0.013 16.0 2.8 0.028 14.9 2.9 1.5 2 0 0 2 2 1 0 Spectrin repeat GAS PF13851.6 CRK41458.1 - 0.016 14.6 3.8 0.02 14.2 3.8 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Pil1 PF13805.6 CRK41458.1 - 0.034 13.6 3.4 0.045 13.2 3.4 1.1 1 0 0 1 1 1 0 Eisosome component PIL1 Spc29 PF17082.5 CRK41458.1 - 0.038 13.8 1.7 0.054 13.3 1.7 1.2 1 0 0 1 1 1 0 Spindle Pole Component 29 Syntaxin-6_N PF09177.11 CRK41458.1 - 0.092 13.3 3.8 0.17 12.5 3.8 1.5 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Med21 PF11221.8 CRK41458.1 - 0.12 12.6 4.0 0.17 12.2 4.0 1.4 1 1 0 1 1 1 0 Subunit 21 of Mediator complex Bcr-Abl_Oligo PF09036.10 CRK41458.1 - 0.13 12.3 1.6 0.39 10.8 1.8 1.7 2 1 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain Fmp27_WPPW PF10359.9 CRK41458.1 - 0.24 10.2 3.0 0.3 9.9 3.0 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Sec20 PF03908.13 CRK41458.1 - 0.29 11.1 1.9 0.34 10.9 0.8 1.6 2 0 0 2 2 2 0 Sec20 CorA PF01544.18 CRK41458.1 - 0.39 10.0 4.2 0.51 9.6 3.1 1.5 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Baculo_PEP_C PF04513.12 CRK41458.1 - 0.42 10.6 2.3 1.2 9.2 0.3 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus XhlA PF10779.9 CRK41458.1 - 0.53 10.5 5.7 4 7.7 2.3 2.2 1 1 1 2 2 2 0 Haemolysin XhlA SlyX PF04102.12 CRK41458.1 - 0.55 10.9 8.6 22 5.8 3.5 2.9 2 1 1 3 3 3 0 SlyX DUF4140 PF13600.6 CRK41458.1 - 2 8.9 6.8 37 4.8 6.8 2.4 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) FRQ PF09421.10 CRK41460.1 - 0 1438.2 50.4 0 1437.8 50.4 1.1 1 0 0 1 1 1 1 Frequency clock protein TBCC PF07986.12 CRK41460.1 - 1e-24 86.6 0.0 1.9e-24 85.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 CRK41460.1 - 3.1e-09 37.3 0.2 1.9e-08 34.7 0.1 2.4 2 0 0 2 2 2 1 Tubulin-specific chaperone C N-terminal domain FlxA PF14282.6 CRK41460.1 - 0.054 13.5 0.3 0.86 9.6 0.1 3.0 2 0 0 2 2 2 0 FlxA-like protein Miga PF10265.9 CRK41460.1 - 1.1 8.1 6.8 1.9 7.4 3.3 2.2 2 0 0 2 2 2 0 Mitoguardin LRR_6 PF13516.6 CRK41464.1 - 5.4e-12 44.7 0.2 0.00023 21.0 0.0 5.2 5 0 0 5 5 5 3 Leucine Rich repeat LRR_4 PF12799.7 CRK41464.1 - 0.002 18.5 0.1 50 4.5 0.0 4.1 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CRK41464.1 - 0.0034 17.7 0.1 52 5.0 0.0 4.5 5 0 0 5 5 5 1 Leucine Rich Repeat MOZ_SAS PF01853.18 CRK41466.1 - 4.8e-53 179.5 0.0 9.5e-53 178.5 0.0 1.4 1 0 0 1 1 1 1 MOZ/SAS family Amino_oxidase PF01593.24 CRK41466.1 - 3e-38 132.3 0.0 4.1e-38 131.8 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase zf-MYST PF17772.1 CRK41466.1 - 2.8e-14 52.5 15.5 0.0064 16.1 0.0 4.9 5 0 0 5 5 5 4 MYST family zinc finger domain NAD_binding_8 PF13450.6 CRK41466.1 - 1.2e-06 28.7 0.0 3.3e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 CRK41466.1 - 0.14 11.5 0.1 0.24 10.7 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ATP-synt_C PF00137.21 CRK41468.1 - 7.6e-11 42.2 12.2 1.8e-10 41.0 12.2 1.6 1 0 0 1 1 1 1 ATP synthase subunit C APOBEC1 PF18769.1 CRK41468.1 - 0.015 15.5 0.0 0.02 15.2 0.0 1.2 1 0 0 1 1 1 0 APOBEC1 SNAD4 PF18750.1 CRK41468.1 - 0.2 11.8 0.0 0.29 11.2 0.0 1.2 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 SAP130_C PF16014.5 CRK41468.1 - 0.38 9.8 3.2 0.44 9.6 3.2 1.0 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus 2-Hacid_dh_C PF02826.19 CRK41470.1 - 1.8e-34 118.6 0.0 2.9e-34 118.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CRK41470.1 - 3.1e-18 65.7 0.0 4.3e-18 65.3 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain DNA_pol_A_exo1 PF01612.20 CRK41475.1 - 3.8e-44 150.5 0.1 6.1e-44 149.8 0.1 1.3 1 0 0 1 1 1 1 3'-5' exonuclease HRDC PF00570.23 CRK41475.1 - 7.1e-27 93.2 0.1 2.3e-12 46.7 0.0 2.8 2 0 0 2 2 2 2 HRDC domain PMC2NT PF08066.12 CRK41475.1 - 2e-25 89.3 0.4 2e-25 89.3 0.4 3.4 3 0 0 3 3 3 1 PMC2NT (NUC016) domain YL1 PF05764.13 CRK41475.1 - 0.0055 16.8 17.2 0.0055 16.8 17.2 3.6 2 1 1 3 3 3 1 YL1 nuclear protein SDA1 PF05285.12 CRK41475.1 - 1.8 7.9 64.0 0.063 12.7 16.6 3.0 3 0 0 3 3 3 0 SDA1 Gpi1 PF05024.15 CRK41477.1 - 4.8e-76 255.0 8.7 8.5e-76 254.2 8.7 1.4 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) MOZ_SAS PF01853.18 CRK41477.1 - 1.5e-47 161.5 0.0 2.7e-47 160.7 0.0 1.4 1 0 0 1 1 1 1 MOZ/SAS family 7tm_1 PF00001.21 CRK41477.1 - 0.0013 18.1 2.0 0.0029 17.0 2.0 1.5 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 2-Hacid_dh_C PF02826.19 CRK41479.1 - 2.4e-35 121.5 0.0 4.4e-35 120.6 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CRK41479.1 - 6.5e-20 71.2 0.1 8.9e-20 70.7 0.1 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain DNA_pol_A_exo1 PF01612.20 CRK41481.1 - 9.8e-45 152.4 0.1 1.6e-44 151.7 0.1 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 CRK41481.1 - 2.4e-26 92.2 0.4 6.3e-26 90.9 0.4 1.8 1 0 0 1 1 1 1 PMC2NT (NUC016) domain Rpn3_C PF08375.11 CRK41484.1 - 2.5e-25 88.7 1.6 2.5e-25 88.7 1.6 1.9 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 CRK41484.1 - 5.9e-22 78.2 0.4 4.3e-21 75.4 0.0 2.5 3 0 0 3 3 3 1 PCI domain TPR_2 PF07719.17 CRK41484.1 - 0.007 16.4 0.1 0.023 14.8 0.1 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 CRK41484.1 - 0.3 11.8 2.2 0.86 10.3 0.5 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TFIID_20kDa PF03847.13 CRK41485.1 - 2.8e-18 66.2 0.0 4.5e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 CRK41485.1 - 0.089 13.1 0.6 0.62 10.4 0.0 2.6 3 0 0 3 3 3 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DASH_Spc34 PF08657.10 CRK41486.1 - 6.4e-39 134.3 0.9 7.7e-21 75.0 0.0 2.6 2 1 1 3 3 3 2 DASH complex subunit Spc34 RNase_H2_suC PF08615.11 CRK41486.1 - 0.0054 16.9 0.3 1.2 9.3 0.0 2.4 2 0 0 2 2 2 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) RXT2_N PF08595.11 CRK41486.1 - 0.084 12.9 11.3 0.11 12.6 0.7 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal BUD22 PF09073.10 CRK41486.1 - 0.19 11.0 12.3 0.83 8.9 2.3 2.1 2 0 0 2 2 2 0 BUD22 Voldacs PF03517.13 CRK41486.1 - 0.59 10.2 7.6 4.8 7.3 2.1 2.3 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling SOGA PF11365.8 CRK41486.1 - 0.76 10.9 7.1 0.12 13.5 1.9 2.1 2 0 0 2 2 2 0 Protein SOGA FYDLN_acid PF09538.10 CRK41486.1 - 0.78 10.4 14.0 3.2 8.5 0.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) CENP-B_dimeris PF09026.10 CRK41486.1 - 1.1 9.7 25.9 1.2 9.5 8.7 2.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain FAM176 PF14851.6 CRK41486.1 - 1.4 8.5 19.8 0.28 10.8 4.9 2.3 2 0 0 2 2 2 0 FAM176 family SDA1 PF05285.12 CRK41486.1 - 4.7 6.6 18.2 1.1 8.6 0.6 2.1 2 0 0 2 2 2 0 SDA1 DASH_Spc19 PF08287.11 CRK41486.1 - 5.9 6.8 11.0 0.82 9.5 4.8 2.1 2 0 0 2 2 2 0 Spc19 S-antigen PF05756.11 CRK41486.1 - 6.1 7.3 8.8 13 6.2 0.1 2.4 2 0 0 2 2 2 0 S-antigen protein Nop14 PF04147.12 CRK41486.1 - 6.1 4.9 21.2 1.8 6.7 4.2 2.1 2 0 0 2 2 2 0 Nop14-like family PTPRCAP PF15713.5 CRK41486.1 - 6.2 7.1 21.3 7 6.9 2.3 2.4 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Sigma70_ner PF04546.13 CRK41486.1 - 6.7 6.5 19.9 7.6 6.4 8.0 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region NOA36 PF06524.12 CRK41486.1 - 9.8 5.4 22.6 7.3 5.8 5.6 2.1 2 0 0 2 2 2 0 NOA36 protein FMO-like PF00743.19 CRK41487.1 - 5.1e-22 78.0 0.0 2.1e-13 49.6 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 CRK41487.1 - 1.7e-11 44.0 0.2 1.9e-09 37.2 0.0 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CRK41487.1 - 3.8e-11 42.8 0.0 4e-10 39.4 0.0 2.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CRK41487.1 - 5e-09 35.7 0.1 6.9e-07 28.7 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) zf-RING_2 PF13639.6 CRK41487.1 - 4.8e-06 26.8 15.3 7.8e-06 26.1 15.3 1.3 1 0 0 1 1 1 1 Ring finger domain NAD_binding_9 PF13454.6 CRK41487.1 - 3.9e-05 23.7 0.2 0.00027 20.9 0.1 2.5 2 1 0 2 2 2 1 FAD-NAD(P)-binding zf-C3HC4 PF00097.25 CRK41487.1 - 0.00056 19.7 11.2 0.00088 19.1 11.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) NAD_binding_8 PF13450.6 CRK41487.1 - 0.0006 20.0 0.3 0.0025 18.0 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CRK41487.1 - 0.0054 16.0 0.3 0.031 13.5 0.1 2.1 2 0 0 2 2 2 1 Thi4 family zf-rbx1 PF12678.7 CRK41487.1 - 0.0058 16.9 11.0 0.011 16.0 11.0 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 CRK41487.1 - 0.01 15.7 10.5 0.016 15.0 10.5 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CRK41487.1 - 0.44 10.6 6.5 1.1 9.3 6.5 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 CRK41487.1 - 0.56 10.1 15.8 0.96 9.3 15.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) MFS_1 PF07690.16 CRK41488.1 - 2e-29 102.6 28.4 2e-29 102.6 28.4 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK41488.1 - 0.0077 15.1 20.5 0.088 11.6 19.9 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter MgtC PF02308.16 CRK41488.1 - 0.038 14.3 7.4 0.2 12.0 0.1 3.2 3 0 0 3 3 3 0 MgtC family Wzy_C PF04932.15 CRK41488.1 - 9.8 5.8 13.2 12 5.5 0.1 3.7 3 1 0 3 3 3 0 O-Antigen ligase Alk_phosphatase PF00245.20 CRK41489.1 - 2.2e-79 267.3 0.0 1.1e-77 261.8 0.0 2.0 1 1 0 1 1 1 1 Alkaline phosphatase ABATE PF07336.11 CRK41489.1 - 0.057 14.1 0.7 0.15 12.7 0.5 1.7 1 1 0 1 1 1 0 Putative stress-induced transcription regulator Metalloenzyme PF01676.18 CRK41489.1 - 0.12 11.8 0.8 0.29 10.5 0.7 1.6 2 0 0 2 2 2 0 Metalloenzyme superfamily DUF2709 PF10915.8 CRK41490.1 - 0.14 11.4 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2709) DNA_methylase PF00145.17 CRK41491.1 - 1.6e-31 109.9 0.0 2.4e-30 106.0 0.0 2.1 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.18 CRK41491.1 - 1.7e-06 27.9 0.0 0.028 14.3 0.0 2.5 2 0 0 2 2 2 2 BAH domain Mt_ATP-synt_D PF05873.12 CRK41492.1 - 0.16 11.8 0.6 7.8 6.3 0.1 2.3 2 0 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) SLATT_4 PF18186.1 CRK41492.1 - 0.3 10.7 1.1 0.87 9.2 0.2 2.0 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 4 Cupin_1 PF00190.22 CRK41493.1 - 0.078 12.6 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Cupin Asp PF00026.23 CRK41495.1 - 3.4e-42 145.0 0.0 3.9e-42 144.8 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 CRK41495.1 - 0.00015 21.6 0.0 0.0033 17.2 0.0 2.6 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal SHMT PF00464.19 CRK41496.1 - 3.6e-206 684.4 0.0 4.2e-206 684.2 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase APT PF03440.14 CRK41497.1 - 0.0025 17.8 0.0 0.0048 16.8 0.0 1.4 1 0 0 1 1 1 1 Aerolysin/Pertussis toxin (APT) domain Bromodomain PF00439.25 CRK41498.1 - 9.1e-20 70.5 0.5 2.5e-19 69.1 0.5 1.8 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.13 CRK41498.1 - 5.3e-07 29.6 0.0 1.2e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated CLZ PF16526.5 CRK41498.1 - 4.6 7.7 7.2 33 4.9 0.1 3.9 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels VanZ PF04892.12 CRK41499.1 - 4.8e-08 33.7 2.0 6.6e-08 33.3 2.0 1.2 1 0 0 1 1 1 1 VanZ like family NAD_binding_6 PF08030.12 CRK41500.1 - 6.6e-07 29.6 0.0 8.5e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 CRK41500.1 - 0.21 12.3 0.0 0.31 11.7 0.0 1.3 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain Gpi1 PF05024.15 CRK41501.1 - 4.3e-76 255.2 8.7 7.7e-76 254.4 8.7 1.4 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) 7tm_1 PF00001.21 CRK41501.1 - 0.001 18.5 2.2 0.003 16.9 2.2 1.8 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Rpn3_C PF08375.11 CRK41503.1 - 1.9e-25 89.1 1.7 1.9e-25 89.1 1.7 1.9 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 CRK41503.1 - 7.4e-22 77.9 0.3 5.6e-21 75.0 0.0 2.5 3 0 0 3 3 3 1 PCI domain TPR_2 PF07719.17 CRK41503.1 - 0.0069 16.4 0.1 0.023 14.8 0.1 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 CRK41503.1 - 0.27 11.9 2.2 0.86 10.3 0.5 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TFIID_20kDa PF03847.13 CRK41504.1 - 3.1e-18 66.0 0.0 5.5e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A SCP2_2 PF13530.6 CRK41504.1 - 0.014 15.8 0.2 0.037 14.4 0.2 1.7 1 0 0 1 1 1 0 Sterol carrier protein domain CBFD_NFYB_HMF PF00808.23 CRK41504.1 - 0.065 13.5 0.4 0.75 10.1 0.0 2.9 3 0 0 3 3 3 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone BAF1_ABF1 PF04684.13 CRK41505.1 - 0.28 10.2 19.6 0.46 9.5 19.6 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DASH_Spc34 PF08657.10 CRK41506.1 - 2.6e-50 171.6 0.0 2.4e-24 86.5 0.0 2.0 1 1 1 2 2 2 2 DASH complex subunit Spc34 SOGA PF11365.8 CRK41506.1 - 0.023 15.8 2.0 0.038 15.1 2.0 1.3 1 0 0 1 1 1 0 Protein SOGA DASH_Spc19 PF08287.11 CRK41506.1 - 0.071 13.0 1.8 0.1 12.5 1.8 1.2 1 0 0 1 1 1 0 Spc19 DUF4140 PF13600.6 CRK41506.1 - 7.8 7.0 8.2 13 6.3 7.4 1.8 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DSBA PF01323.20 CRK41507.1 - 2.6e-40 138.3 0.0 3.8e-40 137.7 0.0 1.2 1 0 0 1 1 1 1 DSBA-like thioredoxin domain zf-RING_2 PF13639.6 CRK41507.1 - 6e-06 26.5 15.4 6e-06 26.5 15.4 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 CRK41507.1 - 0.00048 20.0 11.3 0.00048 20.0 11.3 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Thioredoxin_4 PF13462.6 CRK41507.1 - 0.001 19.3 0.0 0.0028 17.8 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin zf-C3HC4_3 PF13920.6 CRK41507.1 - 0.0029 17.4 10.4 0.0029 17.4 10.4 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CRK41507.1 - 0.0056 16.9 11.2 0.0056 16.9 11.2 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger domain Thioredoxin_5 PF13743.6 CRK41507.1 - 0.062 13.0 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_3 PF13192.6 CRK41507.1 - 0.33 11.0 1.0 14 5.8 0.0 3.1 3 0 0 3 3 3 0 Thioredoxin domain zf-ANAPC11 PF12861.7 CRK41507.1 - 2.6 8.2 10.7 0.9 9.6 6.9 2.2 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 CRK41507.1 - 5.6 6.9 11.8 2.7 7.9 9.0 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 CRK41507.1 - 8 6.4 20.9 0.81 9.6 16.0 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Drc1-Sld2 PF11719.8 CRK41508.1 - 4.2e-98 329.8 22.0 4.8e-98 329.6 22.0 1.0 1 0 0 1 1 1 1 DNA replication and checkpoint protein FMO-like PF00743.19 CRK41509.1 - 1.4e-27 96.3 0.0 9.9e-13 47.3 0.0 4.1 3 1 1 4 4 4 4 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 CRK41509.1 - 8.1e-12 45.0 1.5 4e-09 36.2 0.0 3.8 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CRK41509.1 - 2.7e-11 43.2 0.0 9e-09 35.0 0.0 3.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CRK41509.1 - 1.3e-10 41.0 0.8 5.9e-06 25.6 0.0 4.5 3 1 0 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 CRK41509.1 - 1.4e-06 28.3 0.4 0.00019 21.4 0.1 3.6 4 1 0 4 4 4 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 CRK41509.1 - 0.00041 20.5 0.5 0.0017 18.5 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CRK41509.1 - 0.0022 17.3 0.4 0.021 14.0 0.1 2.1 2 0 0 2 2 2 1 Thi4 family DB_JBP1 PF18526.1 CRK41509.1 - 0.74 9.7 4.2 12 5.8 0.2 2.4 2 0 0 2 2 2 0 Thymine dioxygenase JBP1 DNA-binding domain MFS_1 PF07690.16 CRK41510.1 - 8.9e-30 103.8 27.2 8.9e-30 103.8 27.2 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily MgtC PF02308.16 CRK41510.1 - 0.02 15.3 6.7 0.29 11.5 0.1 3.2 3 0 0 3 3 3 0 MgtC family Wzy_C PF04932.15 CRK41510.1 - 3.9 7.1 12.5 4.7 6.8 0.1 3.7 3 1 0 3 3 3 0 O-Antigen ligase Alk_phosphatase PF00245.20 CRK41511.1 - 6.3e-83 279.0 0.0 7.4e-83 278.8 0.0 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 CRK41511.1 - 0.068 12.5 0.4 0.25 10.7 0.4 1.8 2 0 0 2 2 2 0 Metalloenzyme superfamily ABATE PF07336.11 CRK41511.1 - 0.086 13.5 2.3 0.11 13.2 0.3 2.2 2 0 0 2 2 2 0 Putative stress-induced transcription regulator DNA_methylase PF00145.17 CRK41513.1 - 3.2e-32 112.2 0.0 3e-31 109.0 0.0 2.1 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.18 CRK41513.1 - 3.1e-05 23.8 0.0 0.035 14.0 0.0 2.5 2 0 0 2 2 2 2 BAH domain DUF155 PF02582.14 CRK41514.1 - 3.1e-17 63.2 0.2 5e-17 62.6 0.0 1.4 2 0 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 DUF2362 PF10154.9 CRK41515.1 - 0.22 10.4 0.1 0.33 9.8 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) Asp PF00026.23 CRK41517.1 - 4.4e-112 374.6 0.6 4.9e-112 374.4 0.6 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CRK41517.1 - 9.2e-18 65.1 1.2 3.5e-15 56.7 1.2 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 CRK41517.1 - 1.5e-06 28.8 0.1 0.017 15.7 0.0 3.3 2 2 1 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 CRK41517.1 - 8.1e-06 26.3 0.0 0.011 16.3 0.0 2.8 2 1 0 2 2 2 2 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 CRK41517.1 - 0.00051 19.9 0.0 0.0058 16.4 0.0 2.4 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Alpha-amylase_C PF02806.18 CRK41517.1 - 0.061 13.8 0.2 0.8 10.2 0.0 2.6 2 2 0 2 2 2 0 Alpha amylase, C-terminal all-beta domain SHMT PF00464.19 CRK41518.1 - 4.2e-207 687.5 0.0 4.9e-207 687.3 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Bromodomain PF00439.25 CRK41520.1 - 9.5e-20 70.5 0.5 2.6e-19 69.1 0.5 1.8 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.13 CRK41520.1 - 5.4e-07 29.5 0.0 1.2e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated HEPN_Swt1 PF18731.1 CRK41520.1 - 0.051 13.9 1.2 0.19 12.1 0.2 2.5 2 0 0 2 2 2 0 Swt1-like HEPN ING PF12998.7 CRK41520.1 - 0.32 11.6 3.1 0.58 10.8 0.7 2.6 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding VanZ PF04892.12 CRK41521.1 - 2.4e-08 34.7 2.1 3.4e-08 34.2 2.1 1.2 1 0 0 1 1 1 1 VanZ like family Ferric_reduct PF01794.19 CRK41522.1 - 2.7e-17 63.1 13.7 2.7e-17 63.1 13.7 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 CRK41522.1 - 7.3e-14 52.2 0.0 1.1e-13 51.6 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 CRK41522.1 - 3.1e-10 40.1 0.0 1.4e-05 25.1 0.0 2.5 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_1 PF00175.21 CRK41522.1 - 0.00014 22.4 0.0 0.3 11.8 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain RF-1 PF00472.20 CRK41523.1 - 4.6e-14 52.3 0.5 8e-14 51.6 0.5 1.3 1 0 0 1 1 1 1 RF-1 domain acVLRF1 PF18859.1 CRK41523.1 - 0.046 14.0 1.1 0.078 13.3 1.1 1.3 1 0 0 1 1 1 0 Actinobacteria/chloroflexi VLRF1 release factor BST2 PF16716.5 CRK41525.1 - 0.0023 18.4 4.5 0.0023 18.4 4.5 3.7 3 1 2 5 5 5 1 Bone marrow stromal antigen 2 DUF745 PF05335.13 CRK41525.1 - 0.0093 15.7 19.9 0.0093 15.7 19.9 2.1 2 1 1 3 3 3 1 Protein of unknown function (DUF745) DUF3584 PF12128.8 CRK41525.1 - 0.014 13.0 13.6 0.021 12.3 13.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ADIP PF11559.8 CRK41525.1 - 0.21 11.7 18.0 1.2 9.2 6.1 2.8 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding DUF1664 PF07889.12 CRK41525.1 - 0.69 10.0 8.9 0.6 10.1 1.1 3.3 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) DASH_Duo1 PF08651.10 CRK41525.1 - 1.1 9.1 4.0 1.8 8.4 0.1 3.2 4 0 0 4 4 4 0 DASH complex subunit Duo1 KASH_CCD PF14662.6 CRK41525.1 - 3.3 7.5 18.4 0.022 14.6 8.6 2.3 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH Filament PF00038.21 CRK41525.1 - 6.2 6.3 17.7 0.23 11.0 10.9 2.0 2 1 1 3 3 3 0 Intermediate filament protein PAP2 PF01569.21 CRK41527.1 - 0.011 15.5 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 0 PAP2 superfamily PAP2_3 PF14378.6 CRK41527.1 - 0.09 12.5 1.6 0.13 11.9 1.6 1.3 1 0 0 1 1 1 0 PAP2 superfamily DAP10 PF07213.11 CRK41527.1 - 0.14 12.1 0.1 2.9 7.9 0.0 2.2 2 0 0 2 2 2 0 DAP10 membrane protein KELK PF15796.5 CRK41550.1 - 0.0029 18.0 2.3 0.0029 18.0 2.3 4.8 4 2 1 5 5 5 1 KELK-motif containing domain of MRCK Ser/Thr protein kinase NAD_binding_6 PF08030.12 CRK41552.1 - 9.5e-21 74.5 0.0 1.6e-20 73.8 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 CRK41552.1 - 1.7e-16 60.5 12.6 1.7e-16 60.5 12.6 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 CRK41552.1 - 1.1e-06 28.7 0.0 2.8e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 CRK41552.1 - 0.0019 18.8 0.0 0.18 12.5 0.0 2.6 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FTHFS PF01268.19 CRK41553.1 - 7.7e-202 671.4 0.1 1.5e-104 350.3 0.0 2.2 1 1 1 2 2 2 2 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 CRK41553.1 - 1.5e-69 232.4 2.7 3.8e-69 231.1 1.2 2.2 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 CRK41553.1 - 4.3e-20 72.1 0.2 1.9e-19 70.1 0.1 2.1 1 1 1 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain AlaDh_PNT_C PF01262.21 CRK41553.1 - 0.034 13.5 0.2 0.071 12.4 0.2 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF1997 PF09366.10 CRK41553.1 - 0.14 12.3 0.0 0.57 10.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1997) GTP_EFTU PF00009.27 CRK41553.1 - 0.17 11.4 0.2 0.43 10.1 0.0 1.8 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain WD40 PF00400.32 CRK41555.1 - 2.7e-23 81.8 0.2 1.3e-07 32.1 0.2 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK41555.1 - 1.2e-12 47.9 0.0 0.0045 17.3 0.1 4.8 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CRK41555.1 - 0.00057 18.6 0.0 0.00083 18.1 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 eIF2A PF08662.11 CRK41555.1 - 0.00083 19.3 0.1 2 8.2 0.0 3.0 2 2 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 CRK41555.1 - 0.0021 17.4 0.0 0.03 13.6 0.0 2.2 1 1 0 2 2 2 1 WD40-like domain Coatomer_WDAD PF04053.14 CRK41555.1 - 0.0029 16.7 0.0 0.11 11.5 0.0 2.1 1 1 1 2 2 2 1 Coatomer WD associated region PQQ_2 PF13360.6 CRK41555.1 - 0.0058 16.2 0.0 0.42 10.2 0.0 2.3 1 1 0 1 1 1 1 PQQ-like domain Ge1_WD40 PF16529.5 CRK41555.1 - 0.069 12.1 1.2 7 5.5 0.0 2.6 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4588 PF15251.6 CRK41556.1 - 5.7e-09 36.1 1.7 9.9e-09 35.3 1.7 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) WD40 PF00400.32 CRK41557.1 - 2.7e-25 88.1 23.6 0.00085 20.1 0.2 9.9 10 0 0 10 10 10 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK41557.1 - 1.5e-14 54.0 2.3 9.6e-05 22.6 0.0 5.5 4 2 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CRK41557.1 - 0.00013 21.1 1.7 1.1 8.1 0.0 4.5 4 1 1 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein CPSF_A PF03178.15 CRK41557.1 - 0.0014 18.0 0.0 0.005 16.2 0.0 1.9 3 0 0 3 3 3 1 CPSF A subunit region PQQ_3 PF13570.6 CRK41557.1 - 0.034 14.6 13.3 1.4 9.5 1.0 5.7 5 1 1 6 6 6 0 PQQ-like domain Enoyl_reductase PF12241.8 CRK41557.1 - 0.077 12.3 0.0 0.27 10.5 0.0 1.8 2 0 0 2 2 2 0 Trans-2-enoyl-CoA reductase catalytic region Unstab_antitox PF09720.10 CRK41557.1 - 0.16 12.1 0.0 0.39 10.8 0.0 1.7 1 0 0 1 1 1 0 Putative addiction module component PD40 PF07676.12 CRK41557.1 - 0.47 10.4 4.8 19 5.3 0.0 5.1 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat Glyco_tran_28_C PF04101.16 CRK41558.1 - 2.9e-16 59.9 0.0 5.6e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Raptor_N PF14538.6 CRK41558.1 - 9.5e-07 28.9 0.0 0.03 14.3 0.0 2.6 2 0 0 2 2 2 2 Raptor N-terminal CASPase like domain zf-C2H2 PF00096.26 CRK41558.1 - 0.00062 20.1 13.5 0.082 13.4 0.9 4.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type PapD_N PF00345.20 CRK41558.1 - 0.014 15.3 0.7 6.7 6.6 0.1 2.4 2 0 0 2 2 2 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain Death PF00531.22 CRK41558.1 - 0.099 12.8 0.6 17 5.7 0.1 2.8 2 0 0 2 2 2 0 Death domain CRISPR_Cse2 PF09485.10 CRK41558.1 - 0.099 13.2 4.1 10 6.7 0.4 2.9 2 0 0 2 2 2 0 CRISPR-associated protein Cse2 (CRISPR_cse2) Sina PF03145.16 CRK41558.1 - 0.15 12.0 2.2 0.3 11.0 2.2 1.4 1 0 0 1 1 1 0 Seven in absentia protein family SecA_DEAD PF07517.14 CRK41558.1 - 0.17 11.2 0.0 19 4.5 0.0 2.2 2 0 0 2 2 2 0 SecA DEAD-like domain zf-C2H2_4 PF13894.6 CRK41558.1 - 0.65 11.0 19.7 0.19 12.6 0.9 4.9 4 1 0 4 4 4 0 C2H2-type zinc finger Patatin PF01734.22 CRK41559.1 - 1.7e-11 44.7 0.0 2.1e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Patatin-like phospholipase Patatin PF01734.22 CRK41560.1 - 2.8e-16 60.3 0.2 2.2e-13 50.8 0.0 2.5 2 0 0 2 2 2 2 Patatin-like phospholipase DUF3835 PF12927.7 CRK41560.1 - 0.018 15.9 0.0 17 6.4 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3835) FAM184 PF15665.5 CRK41560.1 - 0.2 11.4 0.0 30 4.3 0.0 2.4 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B 4HBT PF03061.22 CRK41561.1 - 7e-07 29.5 0.0 1.2e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.17 CRK41561.1 - 9.7e-06 25.0 0.6 1.4e-05 24.5 0.6 1.2 1 0 0 1 1 1 1 Acyl-ACP thioesterase 4HBT_2 PF13279.6 CRK41561.1 - 0.00018 22.0 0.0 0.00023 21.6 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily PseudoU_synth_2 PF00849.22 CRK41562.1 - 3.8e-31 108.3 0.0 5.9e-31 107.7 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase DUF3425 PF11905.8 CRK41563.1 - 7.6e-13 48.5 0.3 1.3e-12 47.8 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Packaging_FI PF14000.6 CRK41563.1 - 0.0011 19.4 0.3 0.0021 18.5 0.3 1.4 1 0 0 1 1 1 1 DNA packaging protein FI TSC22 PF01166.18 CRK41563.1 - 0.14 12.5 0.7 1.5 9.2 0.0 2.3 2 0 0 2 2 2 0 TSC-22/dip/bun family ADIP PF11559.8 CRK41563.1 - 0.19 11.8 5.3 0.34 11.0 5.3 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding ABC_tran_CTD PF16326.5 CRK41563.1 - 0.21 11.9 5.3 0.39 11.0 5.3 1.4 1 0 0 1 1 1 0 ABC transporter C-terminal domain DUF1192 PF06698.11 CRK41563.1 - 1.1 9.4 5.5 0.61 10.2 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) bZIP_2 PF07716.15 CRK41563.1 - 1.9 8.6 13.5 6.4 6.9 0.5 2.5 2 0 0 2 2 2 0 Basic region leucine zipper DivIC PF04977.15 CRK41563.1 - 2.2 8.1 8.5 1.4 8.8 0.2 2.7 3 0 0 3 3 3 0 Septum formation initiator bZIP_1 PF00170.21 CRK41563.1 - 2.3 8.4 20.0 0.53 10.4 11.0 3.0 2 1 0 2 2 2 0 bZIP transcription factor SlyX PF04102.12 CRK41563.1 - 5.1 7.8 6.5 87 3.8 1.3 2.6 1 1 1 2 2 2 0 SlyX DUF3425 PF11905.8 CRK41564.1 - 1.7e-13 50.6 0.3 2.6e-13 50.0 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Glyco_hydro_3_C PF01915.22 CRK41566.1 - 3.6e-77 258.9 1.7 1.7e-60 204.4 0.0 3.2 3 0 0 3 3 3 2 Glycosyl hydrolase family 3 C-terminal domain FTA4 PF13093.6 CRK41566.1 - 2.8e-52 177.5 0.3 4.7e-52 176.8 0.3 1.3 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Glyco_hydro_3 PF00933.21 CRK41566.1 - 6.9e-51 173.5 0.0 1e-39 136.8 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 CRK41566.1 - 1e-45 153.7 3.2 1.2e-22 79.8 0.1 3.7 4 0 0 4 4 4 2 Fibronectin type III-like domain PA14 PF07691.12 CRK41566.1 - 1.6e-36 125.3 0.0 8.9e-17 61.3 0.0 3.0 3 0 0 3 3 3 2 PA14 domain DUF1033 PF06279.11 CRK41566.1 - 0.033 14.4 0.2 16 5.7 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1033) FTA4 PF13093.6 CRK41567.1 - 1.5e-55 188.2 0.1 1.9e-55 187.9 0.1 1.1 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 zf-CCHC PF00098.23 CRK41568.1 - 5.6e-45 149.5 59.9 5.8e-08 32.5 2.5 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 CRK41568.1 - 6.6e-10 38.6 39.3 0.16 11.7 1.1 7.1 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_5 PF14787.6 CRK41568.1 - 4.1e-05 23.2 43.1 0.0069 16.1 1.0 7.1 4 2 3 7 7 7 5 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.6 CRK41568.1 - 0.00011 22.1 42.0 0.11 12.5 0.1 6.9 4 2 1 5 5 5 3 Zinc knuckle zf-CCHC_2 PF13696.6 CRK41568.1 - 0.0081 16.0 1.9 0.0081 16.0 1.9 7.1 7 0 0 7 7 7 3 Zinc knuckle zf-CCHC_6 PF15288.6 CRK41568.1 - 0.021 14.7 47.0 0.1 12.4 0.0 6.9 6 1 1 7 7 7 0 Zinc knuckle WD40 PF00400.32 CRK41570.1 - 1.4e-36 123.9 7.1 2.3e-07 31.4 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK41570.1 - 2.3e-12 47.1 0.1 0.0024 18.1 0.0 4.1 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CRK41570.1 - 0.022 14.1 0.0 2.8 7.2 0.1 2.8 2 1 1 3 3 3 0 WD40-like domain Nucleoporin_N PF08801.11 CRK41570.1 - 0.097 11.4 0.3 12 4.5 0.0 2.7 1 1 0 3 3 3 0 Nup133 N terminal like TRAPP PF04051.16 CRK41572.1 - 1.9e-66 222.3 0.1 4.6e-32 110.7 0.0 2.0 1 1 1 2 2 2 2 Transport protein particle (TRAPP) component DUF4250 PF14056.6 CRK41572.1 - 0.00011 22.1 0.5 0.7 9.9 0.1 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4250) PNGaseA PF12222.8 CRK41572.1 - 0.00013 21.0 0.0 0.35 9.7 0.0 2.1 2 0 0 2 2 2 2 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A Meis_PKNOX_N PF16493.5 CRK41572.1 - 0.0052 17.1 0.0 1 9.7 0.0 2.4 2 0 0 2 2 2 1 N-terminal of Homeobox Meis and PKNOX1 Omp28 PF11551.8 CRK41572.1 - 0.013 15.3 0.1 3.9 7.3 0.0 2.2 2 0 0 2 2 2 0 Outer membrane protein Omp28 Synaptonemal_3 PF15191.6 CRK41572.1 - 0.015 15.0 0.0 6.9 6.5 0.0 2.5 2 0 0 2 2 2 0 Synaptonemal complex central element protein 3 DREPP PF05558.12 CRK41572.1 - 0.018 15.0 0.0 5 7.0 0.0 2.1 2 0 0 2 2 2 0 DREPP plasma membrane polypeptide DUF2268 PF10026.9 CRK41572.1 - 0.019 14.5 0.0 3.3 7.2 0.0 2.3 2 0 0 2 2 2 0 Predicted Zn-dependent protease (DUF2268) ComA PF02679.15 CRK41572.1 - 0.023 14.2 0.0 3.9 6.9 0.0 2.2 2 0 0 2 2 2 0 (2R)-phospho-3-sulfolactate synthase (ComA) OMP_b-brl_3 PF14905.6 CRK41572.1 - 0.043 12.8 0.1 7.8 5.4 0.0 2.4 2 0 0 2 2 2 0 Outer membrane protein beta-barrel family Pox_polyA_pol_N PF12630.7 CRK41572.1 - 0.056 13.8 0.0 13 6.2 0.0 2.4 2 0 0 2 2 2 0 Poxvirus poly(A) polymerase N-terminal domain Zmiz1_N PF18028.1 CRK41572.1 - 0.092 13.1 0.1 26 5.2 0.0 2.6 2 0 0 2 2 2 0 Zmiz1 N-terminal tetratricopeptide repeat domain EGL-1 PF11430.8 CRK41572.1 - 0.32 10.9 5.4 18 5.3 0.1 3.8 4 0 0 4 4 4 0 Programmed cell death activator EGL-1 LisH PF08513.11 CRK41573.1 - 0.054 13.5 0.7 0.1 12.6 0.7 1.5 1 0 0 1 1 1 0 LisH DUF1996 PF09362.10 CRK41574.1 - 6.7e-85 284.8 0.2 9e-85 284.4 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) TFB6 PF17110.5 CRK41574.1 - 3.6e-25 88.7 0.5 5.4e-25 88.1 0.5 1.2 1 0 0 1 1 1 1 Subunit 11 of the general transcription factor TFIIH WSC PF01822.19 CRK41574.1 - 7.3e-21 74.2 5.6 2e-20 72.8 5.6 1.8 1 0 0 1 1 1 1 WSC domain STE2 PF02116.15 CRK41576.1 - 5.7e-78 262.1 21.8 6.8e-78 261.8 21.8 1.1 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR IDO PF01231.18 CRK41577.1 - 7.1e-163 542.4 0.0 8.4e-163 542.2 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase RNA_pol_Rpb2_6 PF00562.28 CRK41578.1 - 1e-125 419.9 0.1 1.9e-125 419.0 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 CRK41578.1 - 4e-55 186.5 0.0 1.2e-54 185.0 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 CRK41578.1 - 1.3e-44 152.1 0.0 2.5e-44 151.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 CRK41578.1 - 1.2e-33 115.3 0.1 3e-33 114.1 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 CRK41578.1 - 1.4e-25 89.2 0.1 3.8e-25 87.9 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 CRK41578.1 - 1e-22 80.5 1.4 3.2e-22 78.9 1.4 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_4 PF04566.13 CRK41578.1 - 1.1e-20 73.6 2.7 2.2e-20 72.7 1.4 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 Fer4_19 PF06902.11 CRK41580.1 - 0.09 12.9 0.3 0.16 12.1 0.3 1.3 1 0 0 1 1 1 0 Divergent 4Fe-4S mono-cluster LepA_C PF06421.12 CRK41582.1 - 5.3e-43 145.5 2.3 8.1e-43 145.0 2.3 1.3 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 CRK41582.1 - 8e-19 67.5 0.0 1.3e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 CRK41582.1 - 0.00034 20.7 0.0 0.0012 18.9 0.0 2.0 1 1 0 1 1 1 1 Elongation Factor G, domain II RF3_C PF16658.5 CRK41582.1 - 0.0091 15.8 0.0 0.023 14.5 0.0 1.6 2 0 0 2 2 2 1 Class II release factor RF3, C-terminal domain Snurportin1 PF11538.8 CRK41582.1 - 0.6 10.3 2.9 1.4 9.2 2.9 1.5 1 0 0 1 1 1 0 Snurportin1 adh_short PF00106.25 CRK41584.1 - 4.2e-37 127.5 0.0 5e-37 127.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK41584.1 - 6.5e-32 110.9 0.0 8.1e-32 110.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK41584.1 - 1.2e-09 38.3 0.1 1.6e-09 37.9 0.1 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 CRK41584.1 - 0.043 13.6 0.1 0.11 12.3 0.1 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ERG4_ERG24 PF01222.17 CRK41590.1 - 2.3e-109 366.0 11.1 2.6e-109 365.9 11.1 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family adh_short PF00106.25 CRK41592.1 - 1.3e-18 67.2 0.0 4.6e-17 62.1 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK41592.1 - 4.2e-15 55.9 0.0 4.8e-14 52.5 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK41592.1 - 0.0024 17.8 0.2 0.005 16.8 0.2 1.6 1 1 0 1 1 1 1 KR domain Prefoldin PF02996.17 CRK41595.1 - 3.1e-22 78.7 0.1 3.7e-22 78.5 0.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit Sec2p PF06428.11 CRK41595.1 - 0.0074 16.2 1.7 0.44 10.6 0.1 2.3 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p CLZ PF16526.5 CRK41595.1 - 0.01 16.2 2.2 2.9 8.3 0.1 2.2 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels UDPG_MGDP_dh_N PF03721.14 CRK41595.1 - 0.015 14.9 0.1 0.031 13.9 0.0 1.5 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Fusion_gly PF00523.18 CRK41595.1 - 0.053 11.8 0.1 0.053 11.8 0.1 1.4 2 0 0 2 2 2 0 Fusion glycoprotein F0 YvrJ PF12841.7 CRK41595.1 - 0.11 12.1 0.1 6.4 6.4 0.0 2.3 2 0 0 2 2 2 0 YvrJ protein family BLOC1_2 PF10046.9 CRK41595.1 - 0.12 12.7 2.0 12 6.3 0.1 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GIT_CC PF16559.5 CRK41595.1 - 0.24 11.3 4.6 0.12 12.3 1.3 2.0 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor WXG100 PF06013.12 CRK41595.1 - 0.41 10.9 4.0 11 6.3 0.4 2.1 2 0 0 2 2 2 0 Proteins of 100 residues with WXG tRNA-synt_2b PF00587.25 CRK41596.1 - 1.7e-26 93.3 0.0 3.1e-26 92.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 CRK41596.1 - 3.2e-05 24.0 0.0 6.8e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.20 CRK41596.1 - 0.051 12.7 0.3 0.077 12.1 0.3 1.2 1 0 0 1 1 1 0 tRNA synthetases class II (D, K and N) zinc_ribbon_15 PF17032.5 CRK41596.1 - 0.19 12.5 0.5 0.38 11.5 0.5 1.4 1 0 0 1 1 1 0 zinc-ribbon family adh_short PF00106.25 CRK41601.1 - 2.2e-24 86.0 0.0 2.4e-24 85.9 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK41601.1 - 1.6e-19 70.4 0.0 1.7e-19 70.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK41601.1 - 0.00014 21.8 0.0 0.00029 20.8 0.0 1.6 1 1 0 1 1 1 1 KR domain Glyco_hydro_2_C PF02836.17 CRK41602.1 - 3.5e-05 23.1 1.0 0.00065 18.9 1.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain PWWP PF00855.17 CRK41602.1 - 0.091 13.2 0.0 0.11 12.9 0.0 1.2 1 0 0 1 1 1 0 PWWP domain FMN_dh PF01070.18 CRK41610.1 - 9.2e-21 74.2 0.0 9.7e-21 74.2 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Anth_synt_I_N PF04715.13 CRK41617.1 - 3.1e-24 85.8 0.0 2.7e-23 82.8 0.0 1.9 1 1 0 1 1 1 1 Anthranilate synthase component I, N terminal region DUF4781 PF16013.5 CRK41617.1 - 0.044 12.6 0.0 0.058 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) rhaM PF05336.13 CRK41621.1 - 4.5e-17 62.1 0.1 5.4e-17 61.8 0.1 1.0 1 0 0 1 1 1 1 L-rhamnose mutarotase DUF2433 PF10360.9 CRK41645.1 - 1.6e-25 89.6 0.1 2.2e-25 89.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Ish1 PF10281.9 CRK41649.1 - 1.6e-09 37.9 0.0 2.4e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Putative stress-responsive nuclear envelope protein Frag1 PF10277.9 CRK41653.1 - 7.5e-37 127.0 9.5 8.3e-37 126.8 9.5 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF998 PF06197.13 CRK41653.1 - 0.0012 18.5 17.5 0.0031 17.1 17.5 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF998) SMC_N PF02463.19 CRK41653.1 - 0.21 11.0 0.0 0.33 10.4 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain UbiA PF01040.18 CRK41661.1 - 7.5e-16 58.2 14.3 9.5e-16 57.9 14.3 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Oxidored_molyb PF00174.19 CRK41663.1 - 2.6e-17 63.0 0.0 3.6e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 CRK41663.1 - 3.5e-15 56.2 1.4 1.4e-14 54.3 0.6 2.2 2 1 0 2 2 2 1 Mo-co oxidoreductase dimerisation domain BNR PF02012.20 CRK41663.1 - 0.07 13.2 0.6 0.82 9.9 0.2 2.7 2 0 0 2 2 2 0 BNR/Asp-box repeat Acyltransferase PF01553.21 CRK41673.1 - 2.4e-24 85.5 0.0 5.9e-24 84.2 0.0 1.6 2 0 0 2 2 2 1 Acyltransferase Mon1 PF03164.14 CRK41688.1 - 8.3e-23 81.1 0.0 1.1e-22 80.7 0.0 1.1 1 0 0 1 1 1 1 Trafficking protein Mon1 Methyltransf_15 PF09445.10 CRK41688.1 - 5.4e-20 71.6 0.0 9.7e-20 70.8 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 CRK41688.1 - 0.00031 20.6 0.0 0.00036 20.3 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.15 CRK41688.1 - 0.0092 15.6 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 CRK41688.1 - 0.14 12.9 0.0 0.35 11.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 CRK41688.1 - 0.14 11.1 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase SDH_sah PF01972.16 CRK41688.1 - 0.14 11.1 0.0 0.28 10.1 0.0 1.4 1 0 0 1 1 1 0 Serine dehydrogenase proteinase GRASP55_65 PF04495.14 CRK41690.1 - 2.6e-39 134.7 0.0 2.3e-38 131.7 0.0 2.2 1 1 1 2 2 2 1 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 CRK41690.1 - 0.00093 19.0 0.0 2.1 8.2 0.0 2.7 2 0 0 2 2 2 2 PDZ domain DAD PF02109.16 CRK41692.1 - 4.3e-48 162.1 0.9 5.2e-48 161.9 0.9 1.1 1 0 0 1 1 1 1 DAD family Tmemb_14 PF03647.13 CRK41695.1 - 2.5e-23 82.6 8.6 2.8e-23 82.5 8.6 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C CytB6-F_Fe-S PF08802.10 CRK41695.1 - 6 7.0 10.1 7.9 6.6 0.4 3.0 4 0 0 4 4 4 0 Cytochrome B6-F complex Fe-S subunit Beta_elim_lyase PF01212.21 CRK41697.1 - 1.2e-65 221.7 0.0 1.7e-65 221.2 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Trehalase PF01204.18 CRK41697.1 - 4.2e-38 131.5 5.0 3.1e-37 128.6 5.0 1.9 1 1 0 1 1 1 1 Trehalase Cmc1 PF08583.10 CRK41697.1 - 1.1e-09 38.2 0.8 2e-09 37.3 0.8 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Cys_Met_Meta_PP PF01053.20 CRK41697.1 - 0.00045 18.8 0.0 0.00079 18.1 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Arf PF00025.21 CRK41699.1 - 1.2e-43 148.6 0.1 1.4e-43 148.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 CRK41699.1 - 9.4e-21 74.1 0.0 1.1e-20 73.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CRK41699.1 - 4e-16 59.3 0.0 5.9e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 CRK41699.1 - 4.2e-07 29.6 0.0 5.3e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 CRK41699.1 - 6.8e-06 25.5 0.1 2.2e-05 23.8 0.0 1.8 2 1 0 2 2 2 1 G-protein alpha subunit MMR_HSR1 PF01926.23 CRK41699.1 - 2.3e-05 24.4 0.0 3.4e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 CRK41699.1 - 5.2e-05 22.7 0.0 6.6e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1_Xtn PF16897.5 CRK41699.1 - 0.014 15.4 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Dynamin_N PF00350.23 CRK41699.1 - 0.025 14.6 0.1 1.7 8.7 0.1 2.1 1 1 1 2 2 2 0 Dynamin family RNA_pol_Rpb2_6 PF00562.28 CRK41701.1 - 4.9e-94 315.6 0.0 6.8e-94 315.1 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 CRK41701.1 - 5.1e-54 182.9 0.0 2.4e-31 108.8 0.0 2.2 2 0 0 2 2 2 2 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 CRK41701.1 - 1e-28 99.3 0.0 2.3e-28 98.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.14 CRK41701.1 - 7.7e-26 90.9 0.0 1.4e-25 90.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.12 CRK41701.1 - 1.4e-22 79.4 0.0 2.8e-22 78.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.20 CRK41701.1 - 0.0027 18.1 0.0 0.078 13.4 0.0 2.6 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 Uroplakin_II PF07353.12 CRK41701.1 - 0.021 14.3 0.0 4.4 6.8 0.0 2.3 1 1 1 2 2 2 0 Uroplakin II zinc_ribbon_15 PF17032.5 CRK41701.1 - 0.19 12.5 0.2 0.42 11.4 0.2 1.5 1 0 0 1 1 1 0 zinc-ribbon family Tyrosinase PF00264.20 CRK41702.1 - 5.3e-48 164.2 2.8 1e-47 163.3 2.8 1.5 1 0 0 1 1 1 1 Common central domain of tyrosinase CN_hydrolase PF00795.22 CRK41702.1 - 3.8e-33 114.9 0.0 6.2e-33 114.2 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Tyosinase_C PF18132.1 CRK41702.1 - 1.7e-30 106.2 0.0 3.4e-30 105.2 0.0 1.5 1 0 0 1 1 1 1 Tyosinase C-terminal domain NAD_synthase PF02540.17 CRK41702.1 - 4.2e-22 78.5 0.0 1e-21 77.2 0.0 1.5 1 1 0 1 1 1 1 NAD synthase PTPlike_phytase PF14566.6 CRK41702.1 - 0.097 12.8 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate LSM PF01423.22 CRK41703.1 - 1.9e-16 59.5 0.1 2.8e-16 59.0 0.1 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CRK41703.1 - 0.0019 18.3 0.1 0.0032 17.6 0.1 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain MTS PF05175.14 CRK41704.1 - 0.003 17.1 0.0 0.0058 16.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Enolase_C PF00113.22 CRK41705.1 - 2.7e-151 502.9 0.1 4.1e-151 502.3 0.1 1.3 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Peptidase_M1 PF01433.20 CRK41705.1 - 2.5e-82 275.7 0.1 5.5e-82 274.5 0.1 1.6 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 CRK41705.1 - 4.3e-77 259.8 0.5 8.5e-77 258.8 0.1 1.8 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Enolase_N PF03952.16 CRK41705.1 - 1.1e-55 187.4 0.1 3e-55 186.0 0.1 1.8 1 0 0 1 1 1 1 Enolase, N-terminal domain Peptidase_M1_N PF17900.1 CRK41705.1 - 5.3e-53 180.0 0.3 3.2e-52 177.4 0.1 2.2 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain UDPGP PF01704.18 CRK41705.1 - 2.3e-34 118.8 0.2 2.8e-30 105.3 0.3 2.2 1 1 1 2 2 2 2 UTP--glucose-1-phosphate uridylyltransferase MR_MLE_C PF13378.6 CRK41705.1 - 0.00038 20.1 0.0 0.00076 19.1 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like PKD_channel PF08016.12 CRK41705.1 - 0.075 11.7 5.6 0.73 8.4 0.3 2.3 2 0 0 2 2 2 0 Polycystin cation channel MAAL_C PF07476.11 CRK41705.1 - 0.098 11.8 0.1 0.43 9.7 0.2 1.9 2 0 0 2 2 2 0 Methylaspartate ammonia-lyase C-terminus ING PF12998.7 CRK41707.1 - 8.4e-24 84.1 3.2 1.3e-23 83.5 3.2 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 CRK41707.1 - 0.00011 22.0 9.2 0.00011 22.0 9.2 1.9 2 0 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.6 CRK41707.1 - 0.46 10.9 6.3 0.87 10.0 6.3 1.5 1 0 0 1 1 1 0 Ring finger domain Hist_deacetyl PF00850.19 CRK41709.1 - 1.1e-118 396.2 0.0 7.8e-76 255.5 0.0 2.3 2 1 1 3 3 3 2 Histone deacetylase domain Peptidase_C34 PF05413.11 CRK41709.1 - 0.00011 22.3 0.4 0.88 9.9 0.1 2.6 2 0 0 2 2 2 2 Putative closterovirus papain-like endopeptidase DUF5491 PF17595.2 CRK41709.1 - 0.011 16.1 0.1 4.1 7.8 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5491) Peripla_BP_7 PF18610.1 CRK41709.1 - 0.071 13.2 0.0 19 5.5 0.0 2.4 2 0 0 2 2 2 0 Periplasmic binding protein domain DsrD PF08679.11 CRK41709.1 - 0.084 13.1 0.0 26 5.1 0.0 2.6 2 0 0 2 2 2 0 Dissimilatory sulfite reductase D (DsrD) Glyco_transf_8 PF01501.20 CRK41709.1 - 0.086 12.4 0.1 15 5.1 0.0 2.5 2 0 0 2 2 2 0 Glycosyl transferase family 8 Dicty_CTDC PF00526.18 CRK41709.1 - 5.3 7.0 5.0 38 4.3 0.4 2.6 2 0 0 2 2 2 0 Dictyostelium (slime mold) repeat MFS_1 PF07690.16 CRK41711.1 - 1.5e-15 57.0 14.1 1.5e-15 57.0 14.1 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily RRN3 PF05327.11 CRK41712.1 - 3.6e-132 441.8 0.0 8.2e-99 331.6 0.4 2.9 2 1 1 3 3 3 2 RNA polymerase I specific transcription initiation factor RRN3 Sigma70_ner PF04546.13 CRK41712.1 - 0.037 13.9 10.3 0.053 13.4 0.8 2.6 3 0 0 3 3 3 0 Sigma-70, non-essential region hNIFK_binding PF12196.8 CRK41712.1 - 1.5 8.4 0.0 1.5 8.4 0.0 4.3 3 0 0 3 3 3 0 FHA Ki67 binding domain of hNIFK BUD22 PF09073.10 CRK41712.1 - 9.3 5.5 13.1 2.2 7.5 3.3 2.2 2 0 0 2 2 2 0 BUD22 CBFD_NFYB_HMF PF00808.23 CRK41713.1 - 1.8e-29 101.8 1.0 2.4e-29 101.4 1.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CRK41713.1 - 2.9e-06 27.7 0.0 4.8e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.16 CRK41713.1 - 0.0013 18.7 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 CRK41713.1 - 0.0021 18.1 0.1 0.0034 17.4 0.1 1.3 1 0 0 1 1 1 1 Bromodomain associated CENP-T_C PF15511.6 CRK41713.1 - 0.0027 17.8 0.1 0.0035 17.4 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID_20kDa PF03847.13 CRK41713.1 - 0.067 13.7 0.0 0.11 13.0 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Prefoldin_2 PF01920.20 CRK41718.1 - 6e-24 84.0 12.2 6.9e-24 83.8 12.2 1.0 1 0 0 1 1 1 1 Prefoldin subunit DUF4757 PF15949.5 CRK41718.1 - 0.017 15.6 4.3 0.026 15.0 4.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4757) DUF2205 PF10224.9 CRK41718.1 - 0.018 15.1 1.5 0.018 15.1 1.5 2.1 2 0 0 2 2 2 0 Short coiled-coil protein Prefoldin PF02996.17 CRK41718.1 - 0.018 14.9 7.4 0.38 10.7 0.6 2.2 2 0 0 2 2 2 0 Prefoldin subunit IFT57 PF10498.9 CRK41718.1 - 0.024 13.6 7.8 0.52 9.2 0.8 2.0 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 STAT_alpha PF01017.20 CRK41718.1 - 0.046 13.6 8.9 0.066 13.1 8.9 1.2 1 0 0 1 1 1 0 STAT protein, all-alpha domain FTA4 PF13093.6 CRK41718.1 - 0.05 13.5 6.2 0.14 12.0 6.2 1.7 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 HBB PF06777.11 CRK41718.1 - 0.054 13.2 1.2 0.25 11.0 1.2 1.8 1 1 0 1 1 1 0 Helical and beta-bridge domain DUF4795 PF16043.5 CRK41718.1 - 0.1 12.2 7.2 0.22 11.1 1.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) THOC7 PF05615.13 CRK41718.1 - 0.1 12.9 5.1 1.3 9.3 2.2 2.3 1 1 1 2 2 2 0 Tho complex subunit 7 SLATT_1 PF18181.1 CRK41718.1 - 0.11 12.4 2.3 0.15 12.0 0.4 1.9 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 ZnuA PF01297.17 CRK41718.1 - 0.36 10.2 4.7 1.2 8.5 1.3 2.0 2 0 0 2 2 2 0 Zinc-uptake complex component A periplasmic Cytochrom_B562 PF07361.11 CRK41718.1 - 0.45 11.2 7.6 0.19 12.4 2.3 2.1 1 1 1 2 2 2 0 Cytochrome b562 OmpH PF03938.14 CRK41718.1 - 2.2 8.6 16.1 1 9.7 1.5 2.1 1 1 0 2 2 2 0 Outer membrane protein (OmpH-like) Nore1-SARAH PF16517.5 CRK41718.1 - 2.6 8.0 5.9 0.92 9.5 1.4 2.3 2 0 0 2 2 2 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain FlxA PF14282.6 CRK41718.1 - 4.2 7.4 15.0 6.1 6.9 6.2 2.1 2 0 0 2 2 2 0 FlxA-like protein Rho_Binding PF08912.11 CRK41718.1 - 4.3 8.2 11.9 0.81 10.5 2.7 2.3 2 0 0 2 2 2 0 Rho Binding ubiquitin PF00240.23 CRK41719.1 - 7.8e-25 86.4 0.2 8.8e-25 86.3 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CRK41719.1 - 8.5e-14 51.1 0.1 9.4e-14 51.0 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CRK41719.1 - 0.00039 20.8 0.1 0.0016 18.9 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 CRK41719.1 - 0.0046 16.9 0.0 0.0054 16.6 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_4 PF18036.1 CRK41719.1 - 0.029 14.4 0.3 3.8 7.6 0.2 2.0 2 0 0 2 2 2 0 Ubiquitin-like domain Arf PF00025.21 CRK41720.1 - 9.6e-31 106.6 0.1 1.2e-30 106.3 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CRK41720.1 - 3e-14 53.2 0.0 3.9e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CRK41720.1 - 2.9e-13 49.7 0.0 3.4e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 CRK41720.1 - 1.8e-06 27.5 0.0 2.2e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 CRK41720.1 - 5.1e-06 25.9 0.1 1.6e-05 24.3 0.0 1.7 1 1 1 2 2 2 1 G-protein alpha subunit MMR_HSR1 PF01926.23 CRK41720.1 - 4e-05 23.7 0.0 4.8e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 CRK41720.1 - 0.00033 20.1 0.0 0.00038 19.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 CRK41720.1 - 0.018 15.1 0.1 1.1 9.3 0.1 2.0 1 1 1 2 2 2 0 Dynamin family RNA_pol_Rpb2_6 PF00562.28 CRK41721.1 - 2.5e-95 319.8 1.1 4.9e-83 279.4 0.1 2.1 2 0 0 2 2 2 2 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_3 PF04565.16 CRK41721.1 - 8e-29 99.6 0.0 1.6e-28 98.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.12 CRK41721.1 - 1e-22 79.8 0.0 2e-22 78.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.20 CRK41721.1 - 5.8e-16 58.7 0.0 1.3e-14 54.4 0.0 2.3 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_1 PF04563.15 CRK41721.1 - 6.4e-05 22.6 0.0 0.00027 20.5 0.0 1.9 1 1 1 2 2 2 1 RNA polymerase beta subunit Tyrosinase PF00264.20 CRK41723.1 - 3.7e-48 164.7 3.4 6.5e-48 163.9 3.4 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 CRK41723.1 - 4.8e-29 101.5 0.0 1.1e-28 100.4 0.0 1.6 1 0 0 1 1 1 1 Tyosinase C-terminal domain CN_hydrolase PF00795.22 CRK41723.1 - 4.1e-27 95.1 0.0 6.7e-27 94.5 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 CRK41723.1 - 4.6e-22 78.3 0.0 9.9e-22 77.2 0.0 1.4 1 0 0 1 1 1 1 NAD synthase LSM PF01423.22 CRK41723.1 - 1.5e-15 56.6 0.1 3.4e-15 55.5 0.1 1.6 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CRK41723.1 - 0.012 15.7 0.0 0.026 14.6 0.0 1.5 1 0 0 1 1 1 0 Ataxin 2 SM domain PTPlike_phytase PF14566.6 CRK41723.1 - 0.13 12.4 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate MTS PF05175.14 CRK41727.1 - 0.0031 17.1 0.0 0.0058 16.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Enolase_C PF00113.22 CRK41728.1 - 3e-151 502.7 0.1 4.7e-151 502.1 0.1 1.3 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Peptidase_M1 PF01433.20 CRK41728.1 - 1.2e-81 273.5 0.1 2.6e-81 272.4 0.1 1.6 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 CRK41728.1 - 4.4e-78 263.0 0.7 9.8e-78 261.9 0.1 2.0 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Enolase_N PF03952.16 CRK41728.1 - 1.5e-55 186.9 0.1 3.3e-55 185.8 0.1 1.7 1 0 0 1 1 1 1 Enolase, N-terminal domain Peptidase_M1_N PF17900.1 CRK41728.1 - 2.1e-53 181.3 0.9 8.6e-53 179.3 0.2 2.1 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain DUF3605 PF12239.8 CRK41728.1 - 2.9e-53 180.3 0.6 5.5e-53 179.4 0.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) UDPGP PF01704.18 CRK41728.1 - 5.3e-14 51.7 0.0 5.3e-10 38.5 0.0 2.2 1 1 1 2 2 2 2 UTP--glucose-1-phosphate uridylyltransferase MR_MLE_C PF13378.6 CRK41728.1 - 0.00042 19.9 0.0 0.00085 19.0 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like PKD_channel PF08016.12 CRK41728.1 - 0.041 12.6 6.1 0.27 9.9 0.6 2.2 2 0 0 2 2 2 0 Polycystin cation channel MAAL_C PF07476.11 CRK41728.1 - 0.12 11.5 0.1 0.47 9.6 0.2 1.9 2 0 0 2 2 2 0 Methylaspartate ammonia-lyase C-terminus Ion_trans PF00520.31 CRK41728.1 - 3.7 6.7 15.9 14 4.8 15.9 1.9 1 1 0 1 1 1 0 Ion transport protein FolB PF02152.18 CRK41730.1 - 4.9e-23 81.8 0.1 1.2e-17 64.5 0.1 2.3 2 1 0 2 2 2 2 Dihydroneopterin aldolase ING PF12998.7 CRK41732.1 - 1e-23 83.8 3.1 1.5e-23 83.2 3.1 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 CRK41732.1 - 0.00011 22.0 9.2 0.00011 22.0 9.2 1.9 2 0 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.6 CRK41732.1 - 0.46 10.9 6.3 0.87 10.0 6.3 1.5 1 0 0 1 1 1 0 Ring finger domain Hist_deacetyl PF00850.19 CRK41733.1 - 1.8e-69 234.5 0.0 3.8e-69 233.5 0.0 1.4 2 0 0 2 2 2 1 Histone deacetylase domain MFS_1 PF07690.16 CRK41734.1 - 1.1e-15 57.5 13.7 1.1e-15 57.5 13.7 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily SUN PF03856.13 CRK41735.1 - 7.5e-60 202.4 1.3 8.3e-60 202.3 1.3 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) RRN3 PF05327.11 CRK41738.1 - 5.2e-172 573.3 0.0 5.2e-172 573.3 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 IBN_N PF03810.19 CRK41738.1 - 0.011 15.6 0.0 0.03 14.3 0.0 1.7 1 0 0 1 1 1 0 Importin-beta N-terminal domain Sigma70_ner PF04546.13 CRK41738.1 - 0.15 11.9 10.4 0.17 11.8 0.8 2.5 3 0 0 3 3 3 0 Sigma-70, non-essential region Fmp27 PF10344.9 CRK41738.1 - 0.46 8.5 1.1 0.7 7.9 1.1 1.2 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 hNIFK_binding PF12196.8 CRK41738.1 - 1.9 8.0 0.0 1.9 8.0 0.0 4.2 3 0 0 3 3 3 0 FHA Ki67 binding domain of hNIFK CBFD_NFYB_HMF PF00808.23 CRK41740.1 - 5.5e-14 52.2 0.3 7.4e-14 51.8 0.3 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 CRK41740.1 - 0.0091 16.0 0.0 0.014 15.4 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.24 CRK41740.1 - 0.011 16.1 0.0 0.019 15.3 0.0 1.3 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.16 CRK41740.1 - 0.073 13.1 0.0 0.086 12.9 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit Prefoldin_2 PF01920.20 CRK41742.1 - 6e-24 84.0 12.2 6.9e-24 83.8 12.2 1.0 1 0 0 1 1 1 1 Prefoldin subunit DUF4757 PF15949.5 CRK41742.1 - 0.017 15.6 4.3 0.026 15.0 4.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4757) DUF2205 PF10224.9 CRK41742.1 - 0.018 15.1 1.5 0.018 15.1 1.5 2.1 2 0 0 2 2 2 0 Short coiled-coil protein Prefoldin PF02996.17 CRK41742.1 - 0.018 14.9 7.4 0.38 10.7 0.6 2.2 2 0 0 2 2 2 0 Prefoldin subunit IFT57 PF10498.9 CRK41742.1 - 0.024 13.6 7.8 0.52 9.2 0.8 2.0 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 STAT_alpha PF01017.20 CRK41742.1 - 0.046 13.6 8.9 0.066 13.1 8.9 1.2 1 0 0 1 1 1 0 STAT protein, all-alpha domain FTA4 PF13093.6 CRK41742.1 - 0.05 13.5 6.2 0.14 12.0 6.2 1.7 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 HBB PF06777.11 CRK41742.1 - 0.054 13.2 1.2 0.25 11.0 1.2 1.8 1 1 0 1 1 1 0 Helical and beta-bridge domain DUF4795 PF16043.5 CRK41742.1 - 0.1 12.2 7.2 0.22 11.1 1.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) THOC7 PF05615.13 CRK41742.1 - 0.1 12.9 5.1 1.3 9.3 2.2 2.3 1 1 1 2 2 2 0 Tho complex subunit 7 SLATT_1 PF18181.1 CRK41742.1 - 0.11 12.4 2.3 0.15 12.0 0.4 1.9 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 ZnuA PF01297.17 CRK41742.1 - 0.36 10.2 4.7 1.2 8.5 1.3 2.0 2 0 0 2 2 2 0 Zinc-uptake complex component A periplasmic Cytochrom_B562 PF07361.11 CRK41742.1 - 0.45 11.2 7.6 0.19 12.4 2.3 2.1 1 1 1 2 2 2 0 Cytochrome b562 OmpH PF03938.14 CRK41742.1 - 2.2 8.6 16.1 1 9.7 1.5 2.1 1 1 0 2 2 2 0 Outer membrane protein (OmpH-like) Nore1-SARAH PF16517.5 CRK41742.1 - 2.6 8.0 5.9 0.92 9.5 1.4 2.3 2 0 0 2 2 2 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain FlxA PF14282.6 CRK41742.1 - 4.2 7.4 15.0 6.1 6.9 6.2 2.1 2 0 0 2 2 2 0 FlxA-like protein Rho_Binding PF08912.11 CRK41742.1 - 4.3 8.2 11.9 0.81 10.5 2.7 2.3 2 0 0 2 2 2 0 Rho Binding Band_7 PF01145.25 CRK41744.1 - 2.5e-23 83.0 2.3 4.2e-23 82.3 2.3 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family Elongin_A PF06881.11 CRK41745.1 - 5.8e-23 81.4 1.9 1.5e-22 80.1 1.9 1.7 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A TFIIF_beta_N PF17683.1 CRK41746.1 - 9e-28 97.6 0.0 2e-27 96.5 0.0 1.6 2 0 0 2 2 2 1 TFIIF, beta subunit N-terminus TFIIF_beta PF02270.15 CRK41746.1 - 1.7e-22 79.3 0.3 3.1e-22 78.5 0.3 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain DUF3591 PF12157.8 CRK41746.1 - 0.00036 19.3 0.2 0.00055 18.7 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) HAD PF12710.7 CRK41747.1 - 2.9e-11 44.1 0.0 2.2e-06 28.2 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CRK41747.1 - 1e-05 25.4 0.2 6.5e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CRK41747.1 - 0.0005 20.4 0.0 1.2 9.4 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CRK41747.1 - 0.0091 16.1 0.1 1.1 9.3 0.1 2.3 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase S6PP PF05116.13 CRK41747.1 - 0.024 14.2 0.0 0.18 11.3 0.0 2.0 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase Put_Phosphatase PF06888.12 CRK41747.1 - 0.13 11.6 0.1 11 5.3 0.0 2.2 2 0 0 2 2 2 0 Putative Phosphatase PGP_phosphatase PF09419.10 CRK41747.1 - 0.15 11.6 0.0 0.41 10.3 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase RNase_PH PF01138.21 CRK41752.1 - 6e-13 49.4 0.0 9.9e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 NAD_kinase PF01513.21 CRK41754.1 - 3.7e-82 275.8 0.0 5e-82 275.4 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase Homeodomain PF00046.29 CRK41756.1 - 2.5e-14 52.8 2.8 5.7e-14 51.7 2.8 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CRK41756.1 - 0.059 13.3 0.4 0.15 12.0 0.4 1.7 1 0 0 1 1 1 0 Homeobox KN domain Ras PF00071.22 CRK41758.1 - 9e-49 165.2 0.0 1.2e-48 164.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CRK41758.1 - 2.4e-29 102.0 0.0 5.6e-29 100.8 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CRK41758.1 - 3.6e-11 42.8 0.0 5e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CRK41758.1 - 0.00033 20.7 0.0 0.0006 19.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 CRK41758.1 - 0.00073 19.9 0.1 0.0047 17.3 0.1 2.1 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.12 CRK41758.1 - 0.0014 18.0 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 CRK41758.1 - 0.0029 16.8 1.1 0.17 11.0 0.0 2.5 2 1 1 3 3 3 1 G-protein alpha subunit AAA_7 PF12775.7 CRK41758.1 - 0.0093 15.5 0.1 0.015 14.9 0.1 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region Pox_A32 PF04665.12 CRK41758.1 - 0.014 14.9 0.1 0.024 14.1 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein TsaE PF02367.17 CRK41758.1 - 0.014 15.4 0.2 0.029 14.4 0.2 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 CRK41758.1 - 0.03 14.2 0.1 6.8 6.6 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 CRK41758.1 - 0.051 14.0 0.0 0.099 13.0 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain DAP3 PF10236.9 CRK41758.1 - 0.054 12.7 0.1 0.076 12.2 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_24 PF13479.6 CRK41758.1 - 0.067 12.9 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 CRK41758.1 - 0.078 12.4 0.0 0.13 11.7 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_33 PF13671.6 CRK41758.1 - 0.13 12.4 0.2 0.25 11.5 0.2 1.5 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 CRK41758.1 - 0.23 10.7 0.6 0.29 10.4 0.1 1.5 2 0 0 2 2 2 0 Septin RNase_PH PF01138.21 CRK41760.1 - 2.2e-13 50.9 0.0 4e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 NAD_kinase PF01513.21 CRK41762.1 - 9.1e-81 271.2 0.0 1.3e-80 270.8 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase AGH PF17558.2 CRK41762.1 - 0.15 12.2 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Androgenic gland hormone Ras PF00071.22 CRK41764.1 - 3.3e-40 137.3 0.0 5.6e-40 136.6 0.0 1.3 1 0 0 1 1 1 1 Ras family Nas2_N PF18265.1 CRK41764.1 - 1.9e-26 91.8 0.1 4e-26 90.7 0.1 1.6 1 0 0 1 1 1 1 Nas2 N_terminal domain Roc PF08477.13 CRK41764.1 - 9.7e-21 74.2 0.0 2.3e-20 73.0 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Homeodomain PF00046.29 CRK41764.1 - 3.1e-14 52.5 3.0 1.1e-13 50.8 3.0 2.0 1 0 0 1 1 1 1 Homeodomain Arf PF00025.21 CRK41764.1 - 2.2e-05 24.0 0.0 3.9e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family PDZ_6 PF17820.1 CRK41764.1 - 2.7e-05 23.9 0.0 5.6e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 CRK41764.1 - 5.6e-05 23.4 0.0 0.00018 21.8 0.0 1.8 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 CRK41764.1 - 0.0057 17.0 0.0 0.014 15.7 0.0 1.6 1 0 0 1 1 1 1 PDZ domain Homeobox_KN PF05920.11 CRK41764.1 - 0.09 12.7 0.5 0.27 11.2 0.5 1.8 1 0 0 1 1 1 0 Homeobox KN domain PWI PF01480.17 CRK41767.1 - 4.9e-29 100.4 0.0 1.8e-28 98.7 0.0 1.9 2 0 0 2 2 2 1 PWI domain PWI PF01480.17 CRK41769.1 - 1.8e-29 101.9 0.1 5.5e-29 100.3 0.1 1.8 2 0 0 2 2 2 1 PWI domain Dynamin_M PF01031.20 CRK41771.1 - 3.1e-110 367.9 0.0 6.2e-110 366.9 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 CRK41771.1 - 1.9e-56 190.7 0.0 4.5e-56 189.5 0.0 1.7 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 CRK41771.1 - 2.3e-30 104.6 2.2 2.3e-30 104.6 2.2 2.1 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 CRK41771.1 - 0.00011 22.2 0.4 0.0008 19.5 0.4 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Rad60-SLD PF11976.8 CRK41774.1 - 1.8e-19 69.3 0.1 2.2e-19 69.1 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 CRK41774.1 - 8e-10 38.3 0.0 9.2e-10 38.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family DUF5003 PF16394.5 CRK41774.1 - 0.05 12.7 0.0 0.053 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5003) Mod_r PF07200.13 CRK41776.1 - 4.9e-26 91.6 4.2 4.9e-26 91.6 4.2 1.8 2 0 0 2 2 2 1 Modifier of rudimentary (Mod(r)) protein F-box-like PF12937.7 CRK41776.1 - 5.2e-07 29.5 2.4 6.3e-07 29.2 0.2 2.3 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 CRK41776.1 - 2.6e-06 27.1 0.2 2.6e-06 27.1 0.2 1.9 2 0 0 2 2 2 1 F-box domain HalX PF08663.10 CRK41776.1 - 0.084 13.2 2.2 0.75 10.2 0.1 2.6 2 0 0 2 2 2 0 HalX domain V-ATPase_C PF03223.15 CRK41781.1 - 7e-97 325.1 0.1 8e-97 324.9 0.1 1.0 1 0 0 1 1 1 1 V-ATPase subunit C APS_kinase PF01583.20 CRK41783.1 - 2.8e-71 238.5 0.0 4.6e-71 237.8 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase CBF PF03914.17 CRK41783.1 - 2e-50 171.2 0.4 2.3e-49 167.7 0.3 2.6 2 0 0 2 2 2 1 CBF/Mak21 family AAA_33 PF13671.6 CRK41783.1 - 1.2e-05 25.5 0.0 6.9e-05 23.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CRK41783.1 - 0.00013 22.5 0.0 0.00035 21.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 CRK41783.1 - 0.0071 15.8 0.0 0.019 14.5 0.0 1.7 2 0 0 2 2 2 1 Chromatin associated protein KTI12 tRNA-synt_2b PF00587.25 CRK41785.1 - 1.8e-33 116.0 0.0 8.2e-33 113.9 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 CRK41785.1 - 1e-06 28.8 0.0 2.1e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain Spore_III_AF PF09581.10 CRK41817.1 - 0.77 9.8 5.0 0.87 9.6 5.0 1.0 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) DUF4192 PF13830.6 CRK41817.1 - 0.89 9.6 9.9 0.94 9.5 9.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) Rtf2 PF04641.12 CRK41817.1 - 6.5 6.0 12.6 6.9 5.9 12.6 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger NARP1 PF12569.8 CRK41817.1 - 6.9 5.5 12.8 7.8 5.3 12.8 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF1682 PF07946.14 CRK41817.1 - 9.3 5.3 14.0 11 5.1 14.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Cpn60_TCP1 PF00118.24 CRK41833.1 - 1e-21 77.2 2.2 1.3e-21 76.8 2.2 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family SBE2 PF17076.5 CRK41833.1 - 1.3e-07 30.3 1.0 1.7e-07 29.9 1.0 1.1 1 0 0 1 1 1 1 SBE2, cell-wall formation DUF2462 PF09495.10 CRK41833.1 - 0.038 14.7 0.3 0.48 11.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2462) CRM1_repeat PF18777.1 CRK41833.1 - 0.059 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat Vma12 PF11712.8 CRK41833.1 - 0.13 12.3 0.3 0.26 11.3 0.1 1.6 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF3405 PF11885.8 CRK41846.1 - 4.4e-90 302.7 0.0 4.9e-90 302.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Ribosomal_S6e PF01092.19 CRK41847.1 - 3e-43 146.8 0.0 5.4e-43 145.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S6e Ribosomal_L26 PF16906.5 CRK41850.1 - 1.2e-06 28.8 1.8 1.4e-06 28.7 1.8 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal NOG1 PF06858.14 CRK41858.1 - 1.1e-26 92.4 0.2 1.8e-26 91.7 0.2 1.3 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 CRK41858.1 - 0.00011 22.3 0.0 0.0002 21.4 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CRK41858.1 - 0.03 14.2 0.5 0.081 12.8 0.2 1.8 2 0 0 2 2 2 0 RsgA GTPase NOGCT PF08155.11 CRK41858.1 - 0.03 14.3 0.0 0.059 13.4 0.0 1.5 1 0 0 1 1 1 0 NOGCT (NUC087) domain Sigma54_activ_2 PF14532.6 CRK41858.1 - 0.061 13.4 0.5 0.11 12.6 0.5 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain MMR_HSR1_Xtn PF16897.5 CRK41858.1 - 0.08 13.0 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain RRM_2 PF04059.12 CRK41876.1 - 1.8e-38 130.6 0.4 3e-38 129.9 0.4 1.4 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 CRK41876.1 - 5.9e-05 22.8 0.0 0.19 11.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sad1_UNC PF07738.13 CRK41878.1 - 9e-31 106.6 0.0 1.5e-30 105.9 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal CorA PF01544.18 CRK41878.1 - 0.33 10.2 3.7 0.57 9.4 3.7 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Ribosomal_L3 PF00297.22 CRK41882.1 - 5.1e-16 58.6 0.2 5.4e-16 58.5 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 Pet191_N PF10203.9 CRK41884.1 - 3e-17 62.7 0.7 3.4e-17 62.5 0.7 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 DNA_pol_B PF00136.21 CRK41887.1 - 3e-36 125.1 0.0 3.2e-36 125.0 0.0 1.0 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_2 PF03175.13 CRK41887.1 - 0.0017 17.3 0.0 0.0017 17.3 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DnaJ_C PF01556.18 CRK41897.1 - 0.00024 21.2 0.0 0.00034 20.7 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain ATP-synt_ab_N PF02874.23 CRK41901.1 - 4.1e-10 40.0 1.1 4.4e-10 39.9 1.1 1.0 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Acylphosphatase PF00708.18 CRK41901.1 - 0.051 14.0 0.1 0.054 13.9 0.1 1.2 1 0 0 1 1 1 0 Acylphosphatase DUF5023 PF16426.5 CRK41906.1 - 0.048 13.3 0.1 0.11 12.2 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5023) DUF456 PF04306.13 CRK41912.1 - 0.016 15.5 0.0 0.02 15.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF456) DUF2207 PF09972.9 CRK41912.1 - 0.026 13.3 0.0 0.026 13.3 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) COX14 PF14880.6 CRK41912.1 - 0.028 14.3 0.5 0.078 12.8 0.2 1.7 1 1 1 2 2 2 0 Cytochrome oxidase c assembly Gypsy PF07253.11 CRK41912.1 - 0.052 12.1 0.0 0.059 11.9 0.0 1.0 1 0 0 1 1 1 0 Gypsy protein DUF4448 PF14610.6 CRK41912.1 - 0.068 12.9 0.0 0.09 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Nitrate_red_gam PF02665.14 CRK41912.1 - 0.073 12.6 0.0 0.086 12.4 0.0 1.1 1 0 0 1 1 1 0 Nitrate reductase gamma subunit EphA2_TM PF14575.6 CRK41912.1 - 0.15 13.0 0.0 0.52 11.2 0.0 1.8 1 1 1 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Mid2 PF04478.12 CRK41912.1 - 0.17 11.7 0.0 0.21 11.4 0.0 1.1 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Adeno_E3_CR2 PF02439.15 CRK41912.1 - 0.23 11.3 0.1 0.23 11.3 0.1 1.8 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 BNR PF02012.20 CRK41914.1 - 0.0012 18.5 1.9 1.7 9.0 0.0 3.0 2 0 0 2 2 2 2 BNR/Asp-box repeat BNR_2 PF13088.6 CRK41914.1 - 0.0018 17.6 0.0 0.0051 16.1 0.0 1.7 1 1 0 1 1 1 1 BNR repeat-like domain Sortilin-Vps10 PF15902.5 CRK41914.1 - 0.046 12.5 0.0 4.4 6.0 0.0 2.9 3 0 0 3 3 3 0 Sortilin, neurotensin receptor 3, bZIP_1 PF00170.21 CRK41916.1 - 0.00044 20.3 12.0 0.0076 16.3 12.0 2.3 1 1 0 1 1 1 1 bZIP transcription factor DUF3425 PF11905.8 CRK41916.1 - 0.0016 18.4 0.2 0.0053 16.7 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) ParE_toxin PF05016.15 CRK41916.1 - 0.036 14.7 0.7 0.074 13.7 0.7 1.5 1 0 0 1 1 1 0 ParE toxin of type II toxin-antitoxin system, parDE P4Ha_N PF08336.11 CRK41916.1 - 0.04 13.9 1.2 0.087 12.8 1.2 1.5 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Herpes_BLRF2 PF05812.12 CRK41916.1 - 0.057 13.6 2.1 0.19 11.9 0.8 2.5 2 1 1 3 3 3 0 Herpesvirus BLRF2 protein YHYH PF14240.6 CRK41916.1 - 0.34 10.8 4.3 0.75 9.7 4.3 1.5 1 1 0 1 1 1 0 YHYH protein bZIP_Maf PF03131.17 CRK41916.1 - 0.83 10.2 10.6 0.28 11.7 7.3 2.0 1 1 0 1 1 1 0 bZIP Maf transcription factor FUSC PF04632.12 CRK41916.1 - 4.1 5.8 5.9 6 5.3 5.9 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF572 PF04502.13 CRK41916.1 - 4.4 6.8 10.0 6.8 6.2 10.0 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF572) Lysine_decarbox PF03641.14 CRK41918.1 - 3.9e-28 98.2 0.0 5.8e-28 97.6 0.0 1.3 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 CRK41918.1 - 3.3e-09 36.5 0.4 5.5e-09 35.8 0.4 1.3 1 0 0 1 1 1 1 SLOG cluster4 family LSDAT_prok PF18171.1 CRK41918.1 - 0.098 11.9 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 SLOG in TRPM, prokaryote PTPLA PF04387.14 CRK41920.1 - 6.9e-39 133.2 10.7 6.9e-39 133.2 10.7 2.6 3 0 0 3 3 3 1 Protein tyrosine phosphatase-like protein, PTPLA Zn_clus PF00172.18 CRK41920.1 - 0.00034 20.7 10.2 0.00069 19.7 10.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NACHT PF05729.12 CRK41924.1 - 6.3e-09 36.0 0.1 1.5e-08 34.8 0.1 1.6 1 0 0 1 1 1 1 NACHT domain ANAPC4_WD40 PF12894.7 CRK41924.1 - 6.5e-09 36.0 0.0 0.26 11.6 0.0 5.0 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CRK41924.1 - 4.8e-08 33.6 0.0 0.97 10.4 0.0 6.5 7 0 0 7 7 5 2 WD domain, G-beta repeat PGAP1 PF07819.13 CRK41924.1 - 8.2e-06 25.7 0.0 2.1e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 PGAP1-like protein Frtz PF11768.8 CRK41924.1 - 0.0002 19.8 0.2 0.0037 15.7 0.0 2.2 2 0 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz DUF676 PF05057.14 CRK41924.1 - 0.00052 19.6 0.0 0.0012 18.4 0.0 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 CRK41924.1 - 0.01 16.5 0.0 0.087 13.4 0.0 2.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family AAA_33 PF13671.6 CRK41924.1 - 0.024 14.8 0.0 12 6.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain eIF2A PF08662.11 CRK41924.1 - 0.039 13.8 0.0 0.24 11.3 0.0 2.2 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A DUF2075 PF09848.9 CRK41924.1 - 0.046 13.0 0.1 2.4 7.3 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) LCAT PF02450.15 CRK41924.1 - 0.073 12.2 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.8 CRK41924.1 - 0.091 12.0 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 NB-ARC PF00931.22 CRK41924.1 - 0.11 11.7 0.0 0.23 10.6 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Abhydrolase_1 PF00561.20 CRK41924.1 - 0.12 12.0 0.1 1.8 8.1 0.0 2.3 2 0 0 2 2 2 0 alpha/beta hydrolase fold MFS_1 PF07690.16 CRK41925.1 - 3.2e-28 98.7 20.6 3.2e-28 98.7 20.6 2.7 1 1 2 3 3 3 2 Major Facilitator Superfamily DUF3464 PF11947.8 CRK41925.1 - 0.0051 16.6 0.1 0.013 15.3 0.1 1.6 1 0 0 1 1 1 1 Photosynthesis affected mutant 68 MatE PF01554.18 CRK41926.1 - 4.2e-53 179.3 26.6 2.5e-35 121.5 8.9 2.2 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 CRK41926.1 - 4.4e-05 23.6 2.1 4.4e-05 23.6 2.1 3.9 3 2 1 4 4 4 1 Polysaccharide biosynthesis C-terminal domain DUF5389 PF17364.2 CRK41926.1 - 0.029 14.4 0.1 0.029 14.4 0.1 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5389) Indigoidine_A PF04227.12 CRK41927.1 - 1.3e-107 359.5 1.4 1.9e-107 359.0 1.4 1.2 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 CRK41927.1 - 8.4e-20 71.3 3.4 2e-16 60.2 3.3 3.6 1 1 0 1 1 1 1 pfkB family carbohydrate kinase SLD5_C PF16922.5 CRK41929.1 - 1.5e-12 47.5 0.0 2.8e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 CRK41929.1 - 1.5e-06 28.6 0.0 2.8e-06 27.7 0.0 1.5 1 1 0 1 1 1 1 GINS complex protein Na_Ca_ex PF01699.24 CRK41930.1 - 1.5e-24 86.7 10.3 1.5e-24 86.7 10.3 1.6 2 0 0 2 2 2 1 Sodium/calcium exchanger protein Cnd2 PF05786.14 CRK41931.1 - 3.2e-139 465.9 7.7 3.8e-139 465.7 7.7 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 CRK41931.1 - 0.0021 18.3 0.1 0.0021 18.3 0.1 2.2 2 0 0 2 2 2 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal MPP6 PF10175.9 CRK41931.1 - 0.14 12.7 7.4 9.1 6.8 4.6 2.4 2 0 0 2 2 2 0 M-phase phosphoprotein 6 FAM176 PF14851.6 CRK41931.1 - 0.29 10.8 11.8 2.2 7.9 2.9 3.1 3 0 0 3 3 3 0 FAM176 family Vfa1 PF08432.10 CRK41931.1 - 1.8 8.9 9.2 0.49 10.7 2.6 2.4 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DUF5520 PF17658.1 CRK41931.1 - 2 7.5 10.3 2.9 6.9 2.6 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5520) RXT2_N PF08595.11 CRK41931.1 - 6.9 6.7 10.9 5.2 7.1 1.6 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal Na_Ca_ex PF01699.24 CRK41933.1 - 1.2e-27 96.7 19.2 1.2e-27 96.7 19.2 1.5 2 0 0 2 2 2 1 Sodium/calcium exchanger protein p53-inducible11 PF14936.6 CRK41933.1 - 0.0099 15.9 3.5 0.029 14.4 2.7 1.9 1 1 1 2 2 2 1 Tumour protein p53-inducible protein 11 DUF5592 PF17332.2 CRK41933.1 - 0.058 14.0 1.1 0.058 14.0 1.1 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5592) DUF2070 PF09843.9 CRK41933.1 - 7.7 4.7 10.6 14 3.8 10.6 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Cnd2 PF05786.14 CRK41934.1 - 2.8e-189 631.5 1.8 3.4e-189 631.2 1.8 1.1 1 0 0 1 1 1 1 Condensin complex subunit 2 HAMP PF00672.25 CRK41937.1 - 5.7e-67 221.9 34.0 4.9e-07 30.0 0.1 12.9 11 0 0 11 11 11 9 HAMP domain Response_reg PF00072.24 CRK41937.1 - 6.6e-46 155.1 4.3 1.2e-25 89.9 0.3 3.5 3 0 0 3 3 3 2 Response regulator receiver domain HATPase_c PF02518.26 CRK41937.1 - 4e-30 104.6 1.0 1.3e-29 103.0 0.1 2.5 2 0 0 2 2 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 CRK41937.1 - 1.3e-16 60.3 0.5 1.3e-16 60.3 0.5 4.8 5 0 0 5 5 5 1 His Kinase A (phospho-acceptor) domain Syntaxin_2 PF14523.6 CRK41937.1 - 6e-12 45.8 33.6 3.5 8.1 0.0 12.3 7 3 2 11 11 11 3 Syntaxin-like protein DUF4279 PF14106.6 CRK41937.1 - 3.3e-07 30.5 0.0 69 3.7 0.0 9.0 10 0 0 10 10 10 0 Domain of unknown function (DUF4279) DUF948 PF06103.11 CRK41937.1 - 5.6e-06 26.5 85.2 0.69 10.2 4.7 15.7 8 4 3 11 11 11 3 Bacterial protein of unknown function (DUF948) GLE1 PF07817.13 CRK41937.1 - 2e-05 24.0 11.3 6.2 5.9 0.0 7.0 3 2 4 7 7 7 2 GLE1-like protein Fib_alpha PF08702.10 CRK41937.1 - 0.0005 20.3 56.9 0.12 12.5 0.7 10.7 10 3 3 13 13 13 4 Fibrinogen alpha/beta chain family DUF1759 PF03564.15 CRK41937.1 - 0.0038 17.2 4.2 1.4e+02 2.4 0.0 7.1 6 1 1 7 7 7 0 Protein of unknown function (DUF1759) HTH_6 PF01418.17 CRK41937.1 - 0.0044 17.0 0.0 31 4.6 0.0 4.6 5 0 0 5 5 3 0 Helix-turn-helix domain, rpiR family Peptidase_C23 PF05379.11 CRK41937.1 - 0.0052 16.9 1.0 8.2 6.6 0.1 3.6 2 0 0 2 2 2 0 Carlavirus endopeptidase TetR_C_5 PF08360.11 CRK41937.1 - 0.014 15.6 0.2 20 5.4 0.0 3.8 2 0 0 2 2 2 0 QacR-like protein, C-terminal region GhoS PF11080.8 CRK41937.1 - 0.016 15.2 14.9 6.9 6.7 0.0 6.9 7 0 0 7 7 7 0 Endoribonuclease GhoS Duffy_binding PF05424.11 CRK41937.1 - 0.028 14.5 2.8 12 5.9 0.1 4.3 3 0 0 3 3 3 0 Duffy binding domain DUF3829 PF12889.7 CRK41937.1 - 0.053 13.0 21.3 13 5.1 0.1 7.7 7 4 2 9 9 9 0 Protein of unknown function (DUF3829) Coat_F PF07875.12 CRK41937.1 - 0.062 13.5 0.2 71 3.7 0.0 4.5 4 0 0 4 4 2 0 Coat F domain UBD PF16455.5 CRK41937.1 - 0.065 13.5 7.1 3.2 8.0 0.2 3.7 3 1 1 4 4 4 0 Ubiquitin-binding domain UME PF08064.13 CRK41937.1 - 0.17 11.8 3.1 20 5.2 0.2 3.3 2 0 0 2 2 2 0 UME (NUC010) domain Laminin_II PF06009.12 CRK41937.1 - 0.17 11.9 69.0 1.5 8.8 0.2 12.4 9 4 4 13 13 13 0 Laminin Domain II AdHead_fibreRBD PF16812.5 CRK41937.1 - 0.2 11.5 7.7 5.8 6.7 0.2 3.8 3 0 0 3 3 3 0 C-terminal head domain of the fowl adenovirus type 1 long fibre Cadherin_2 PF08266.12 CRK41937.1 - 0.24 11.3 2.2 34 4.3 0.2 3.5 2 0 0 2 2 2 0 Cadherin-like TPR_2 PF07719.17 CRK41937.1 - 0.39 11.0 4.0 22 5.5 0.3 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4795 PF16043.5 CRK41937.1 - 0.56 9.8 48.3 0.25 10.9 0.6 8.9 2 2 3 7 7 7 0 Domain of unknown function (DUF4795) Wtap PF17098.5 CRK41937.1 - 0.85 9.5 16.3 15 5.5 4.1 4.8 2 2 0 2 2 2 0 WTAP/Mum2p family PEP-utilisers_N PF05524.13 CRK41937.1 - 2.8 8.1 26.2 2.4 8.3 1.8 7.2 5 3 0 7 7 7 0 PEP-utilising enzyme, N-terminal DUF3391 PF11871.8 CRK41937.1 - 3.8 8.1 11.7 31 5.1 2.2 3.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) C2 PF00168.30 CRK41938.1 - 2.6e-37 127.3 0.4 3.9e-17 62.4 0.1 2.7 2 0 0 2 2 2 2 C2 domain Membr_traf_MHD PF10540.9 CRK41938.1 - 3.5e-35 121.4 6.4 1.1e-14 54.8 0.7 5.0 2 2 0 2 2 2 2 Munc13 (mammalian uncoordinated) homology domain HTH_Tnp_Tc3_2 PF01498.18 CRK41938.1 - 2.9e-05 24.2 1.5 0.31 11.3 0.1 3.1 2 0 0 2 2 2 2 Transposase AIM5 PF17050.5 CRK41938.1 - 0.015 16.1 0.8 14 6.5 0.1 3.2 2 0 0 2 2 2 0 Altered inheritance of mitochondria 5 HTH_32 PF13565.6 CRK41938.1 - 0.015 15.9 1.0 13 6.5 0.1 3.3 2 0 0 2 2 2 0 Homeodomain-like domain HTH_21 PF13276.6 CRK41938.1 - 0.054 13.6 0.0 28 4.9 0.0 3.4 4 0 0 4 4 4 0 HTH-like domain Porphyrn_cat_1 PF18206.1 CRK41938.1 - 0.062 13.9 0.3 26 5.5 0.0 2.8 2 0 0 2 2 2 0 Porphyranase catalytic subdomain 1 HTH_33 PF13592.6 CRK41938.1 - 0.1 12.2 0.2 28 4.4 0.0 3.0 2 0 0 2 2 2 0 Winged helix-turn helix BAR_3 PF16746.5 CRK41939.1 - 7.5e-22 78.2 10.9 1.1e-21 77.6 10.9 1.1 1 0 0 1 1 1 1 BAR domain of APPL family PilJ PF13675.6 CRK41939.1 - 0.075 13.1 1.5 0.11 12.5 0.2 2.0 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term EMP24_GP25L PF01105.24 CRK41939.1 - 0.21 11.5 2.2 2 8.3 1.9 2.3 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD ArfGap PF01412.18 CRK41942.1 - 1.3e-32 112.3 0.0 4.5e-32 110.6 0.0 2.0 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 CRK41942.1 - 1.1e-16 61.3 9.7 1.7e-16 60.7 9.7 1.2 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 CRK41942.1 - 1.8e-12 47.7 0.7 6.3e-12 45.9 0.2 2.3 2 0 0 2 2 2 1 PH domain PH_9 PF15410.6 CRK41942.1 - 0.31 11.4 2.9 1.7 9.0 0.4 3.0 2 1 0 2 2 2 0 Pleckstrin homology domain Phage_GP20 PF06810.11 CRK41942.1 - 2.1 8.2 6.0 0.37 10.6 0.8 2.3 2 0 0 2 2 2 0 Phage minor structural protein GP20 Pkinase PF00069.25 CRK41944.1 - 9.3e-43 146.5 0.0 2.5e-25 89.3 0.2 2.3 1 1 1 2 2 2 2 Protein kinase domain FHA PF00498.26 CRK41944.1 - 2.1e-17 63.2 0.1 4.2e-17 62.3 0.1 1.5 1 0 0 1 1 1 1 FHA domain Pkinase_Tyr PF07714.17 CRK41944.1 - 2.2e-17 63.2 1.3 5.8e-15 55.3 0.4 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Yop-YscD_cpl PF16697.5 CRK41944.1 - 1.9e-09 37.7 0.0 4.2e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Kinase-like PF14531.6 CRK41944.1 - 0.0018 17.6 0.1 0.31 10.3 0.0 2.2 2 0 0 2 2 2 2 Kinase-like FHA_2 PF17913.1 CRK41944.1 - 0.077 13.2 0.1 0.21 11.8 0.0 1.7 2 0 0 2 2 2 0 FHA domain DUF2961 PF11175.8 CRK41944.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2961) PCI PF01399.27 CRK41946.1 - 4.2e-14 52.9 0.2 1.9e-13 50.8 0.0 2.2 2 0 0 2 2 2 1 PCI domain eIF3m_C_helix PF18005.1 CRK41946.1 - 3.2e-11 42.7 2.6 3.2e-11 42.7 2.6 1.8 2 0 0 2 2 2 1 eIF3 subunit M, C-terminal helix AnfO_nitrog PF09582.10 CRK41946.1 - 0.027 13.8 0.2 0.39 10.0 0.0 2.2 2 0 0 2 2 2 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) ADK PF00406.22 CRK41947.1 - 5.2e-43 146.7 0.0 7e-43 146.3 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CRK41947.1 - 1.4e-33 116.2 0.0 1.9e-33 115.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CRK41947.1 - 2.1e-06 28.3 0.0 3.3e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CRK41947.1 - 1.4e-05 25.3 0.0 4.4e-05 23.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 CRK41947.1 - 0.003 17.3 0.0 1.2 8.8 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase Pro_isomerase PF00160.21 CRK41948.1 - 5.9e-50 169.6 0.0 1.2e-49 168.6 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 CRK41948.1 - 1.3e-10 41.7 0.0 0.00083 20.1 0.0 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK41948.1 - 0.00027 21.1 0.0 0.26 11.6 0.0 2.7 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CRK41948.1 - 0.033 13.2 0.4 1.5 7.7 0.1 2.8 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Aldedh PF00171.22 CRK41949.1 - 4.6e-131 437.5 0.2 5.6e-131 437.2 0.2 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Aldolase_II PF00596.21 CRK41951.1 - 2.1e-43 148.4 0.0 2.5e-43 148.2 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DSPn PF14671.6 CRK41953.1 - 0.13 12.7 0.5 2.2 8.7 0.5 2.2 1 1 0 1 1 1 0 Dual specificity protein phosphatase, N-terminal half Pyrophosphatase PF00719.19 CRK41954.1 - 3.6e-56 189.4 0.2 5.8e-56 188.7 0.2 1.3 1 0 0 1 1 1 1 Inorganic pyrophosphatase Sec20 PF03908.13 CRK41954.1 - 1e-08 35.0 0.0 1e-08 35.0 0.0 3.2 4 0 0 4 4 4 1 Sec20 UPF0242 PF06785.11 CRK41954.1 - 0.11 12.6 4.5 0.24 11.5 4.5 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Flg_hook PF02120.16 CRK41954.1 - 0.37 10.7 3.7 0.71 9.8 0.1 2.7 3 0 0 3 3 3 0 Flagellar hook-length control protein FliK DUF2312 PF10073.9 CRK41954.1 - 9.4 6.0 6.6 0.51 10.0 0.1 2.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2312) MRP_L53 PF10780.9 CRK41955.1 - 1e-19 70.4 0.7 1.4e-19 70.0 0.7 1.2 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 Ecotin PF03974.13 CRK41955.1 - 0.04 13.9 0.0 0.05 13.6 0.0 1.1 1 0 0 1 1 1 0 Ecotin KorB_C PF06613.11 CRK41955.1 - 0.12 12.4 0.0 0.33 11.0 0.0 1.7 1 1 1 2 2 2 0 KorB C-terminal beta-barrel domain Dus PF01207.17 CRK41958.1 - 3e-40 138.2 0.2 3.5e-39 134.7 0.2 2.0 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) ApoO PF09769.9 CRK41960.1 - 6.4e-40 136.1 1.7 4.6e-39 133.4 0.1 2.5 3 0 0 3 3 3 1 Apolipoprotein O Peptidase_M3 PF01432.20 CRK41962.1 - 7.9e-133 444.1 0.0 7e-82 276.1 0.0 2.2 1 1 1 2 2 2 2 Peptidase family M3 LigT_PEase PF02834.16 CRK41962.1 - 0.00014 21.9 0.0 1.3 9.2 0.0 2.9 2 0 0 2 2 2 2 LigT like Phosphoesterase Peptidase_M50B PF13398.6 CRK41962.1 - 0.011 15.4 0.1 0.018 14.7 0.1 1.2 1 0 0 1 1 1 0 Peptidase M50B-like Yae1_N PF09811.9 CRK41963.1 - 1.8e-05 24.3 3.7 2.7e-05 23.8 3.0 1.6 1 1 1 2 2 2 2 Essential protein Yae1, N terminal Lipase_GDSL_2 PF13472.6 CRK41964.1 - 3.8e-21 76.3 3.6 5.9e-21 75.7 3.6 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 CRK41964.1 - 1.8e-08 34.6 0.0 3e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase BOP1NT PF08145.12 CRK41965.1 - 1.5e-95 320.1 7.7 2.1e-95 319.6 7.7 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 CRK41965.1 - 1e-24 86.3 4.1 8.6e-12 45.4 0.2 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK41965.1 - 2.1e-07 31.2 0.1 0.002 18.4 0.0 4.0 3 3 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 CRK41965.1 - 0.00057 18.3 0.0 2.1 6.6 0.0 3.0 2 1 1 3 3 3 3 WD repeat-containing and planar cell polarity effector protein Fritz STIMATE PF12400.8 CRK41967.1 - 6.6e-41 139.8 3.9 6.6e-41 139.8 3.9 1.6 2 0 0 2 2 2 1 STIMATE family TNFR_16_TM PF18422.1 CRK41967.1 - 0.97 9.5 3.1 42 4.2 1.8 2.5 2 0 0 2 2 2 0 Tumor necrosis factor receptor member 16 trans-membrane domain GP41 PF00517.17 CRK41968.1 - 0.044 13.7 0.1 0.066 13.1 0.1 1.2 1 0 0 1 1 1 0 Retroviral envelope protein Corona_S2 PF01601.16 CRK41968.1 - 0.062 11.8 17.6 0.088 11.3 17.6 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein MFS_1 PF07690.16 CRK41979.1 - 2.2e-07 30.1 13.7 3.2e-07 29.6 13.7 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1275 PF06912.11 CRK41979.1 - 0.16 11.9 11.1 1.7 8.5 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1275) Septin PF00735.18 CRK41983.1 - 4.8e-33 114.6 2.9 6.7e-33 114.2 0.0 2.0 2 0 0 2 2 2 1 Septin AP1AR PF15745.5 CRK41983.1 - 0.048 13.3 7.9 0.056 13.1 7.9 1.2 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein Exonuc_VII_L PF02601.15 CRK41983.1 - 0.1 12.1 8.0 0.13 11.9 8.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Caldesmon PF02029.15 CRK41983.1 - 0.37 9.5 20.8 0.44 9.3 20.8 1.2 1 0 0 1 1 1 0 Caldesmon Atg14 PF10186.9 CRK41983.1 - 0.67 9.0 8.1 0.86 8.6 8.1 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 UPF0242 PF06785.11 CRK41983.1 - 1.1 9.3 15.6 1.4 9.0 15.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus MnmE_helical PF12631.7 CRK41983.1 - 1.6 8.8 5.9 2 8.5 5.9 1.1 1 0 0 1 1 1 0 MnmE helical domain Strep_SA_rep PF06696.11 CRK41983.1 - 3.7 7.6 8.4 0.16 12.0 0.9 2.2 2 0 0 2 2 2 0 Streptococcal surface antigen repeat GDC-P PF02347.16 CRK41988.1 - 2.2e-84 283.8 0.1 2.4e-84 283.6 0.1 1.0 1 0 0 1 1 1 1 Glycine cleavage system P-protein Cys_Met_Meta_PP PF01053.20 CRK41988.1 - 0.0009 17.9 0.0 0.0012 17.4 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Lipase_GDSL PF00657.22 CRK42000.1 - 0.0037 17.3 0.0 0.0078 16.2 0.0 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase TIM PF00121.18 CRK42007.1 - 1.2e-77 260.6 0.3 1.3e-77 260.5 0.3 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase eIF-5_eIF-2B PF01873.17 CRK42008.1 - 6.4e-40 135.7 0.0 1.1e-39 134.9 0.0 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 DUF1774 PF08611.10 CRK42016.1 - 2e-25 88.9 0.3 2.2e-25 88.8 0.3 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1774) DUF5560 PF17715.1 CRK42016.1 - 0.074 12.5 0.0 0.083 12.3 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5560) SUN PF03856.13 CRK42022.1 - 5.8e-12 45.6 0.8 7.7e-12 45.2 0.8 1.2 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) EFG_IV PF03764.18 CRK42022.1 - 0.0049 16.6 0.0 0.066 13.0 0.1 2.2 2 0 0 2 2 2 1 Elongation factor G, domain IV AtuA PF07287.11 CRK42024.1 - 2.8e-49 167.7 0.0 3.3e-49 167.5 0.0 1.0 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA Methyltr_RsmB-F PF01189.17 CRK42033.1 - 6.5e-05 22.7 0.0 9.2e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 CRK42033.1 - 0.17 12.0 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase MmgE_PrpD PF03972.14 CRK42037.1 - 1.7e-46 158.7 0.0 4.8e-46 157.2 0.0 1.6 2 0 0 2 2 2 1 MmgE/PrpD family DSPc PF00782.20 CRK42048.1 - 1.5e-09 37.7 0.0 2.8e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain UPF0121 PF03661.13 CRK42048.1 - 1.9e-06 27.4 0.0 2.7e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) Y_phosphatase PF00102.27 CRK42048.1 - 0.00038 20.1 0.2 0.0028 17.2 0.2 2.1 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 CRK42048.1 - 0.018 15.0 0.0 0.036 14.0 0.0 1.5 2 0 0 2 2 2 0 Tyrosine phosphatase family Bac_rhamnosid6H PF17389.2 CRK42050.1 - 2.9e-08 33.4 0.7 1.8e-07 30.7 1.2 1.9 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Glyco_transf_22 PF03901.17 CRK42052.1 - 4.1e-84 283.2 13.8 5.1e-84 282.9 13.8 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Glyco_transf_22 PF03901.17 CRK42054.1 - 4.4e-84 283.1 14.1 5.2e-84 282.9 14.1 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DSPc PF00782.20 CRK42056.1 - 1.3e-07 31.5 0.0 2.2e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CRK42056.1 - 0.01 15.4 0.3 0.038 13.6 0.3 1.8 1 1 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 CRK42056.1 - 0.14 12.1 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family FAD_binding_2 PF00890.24 CRK42062.1 - 1.5e-25 90.1 0.0 2.1e-25 89.7 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 CRK42062.1 - 0.096 12.0 0.3 0.43 9.9 0.3 2.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase SUR7 PF06687.12 CRK42064.1 - 8.6e-23 81.1 3.8 1.1e-22 80.8 3.8 1.1 1 0 0 1 1 1 1 SUR7/PalI family Phage_holin_4_2 PF04020.13 CRK42064.1 - 0.038 14.7 4.7 0.045 14.4 1.3 2.0 2 0 0 2 2 2 0 Mycobacterial 4 TMS phage holin, superfamily IV DUF1218 PF06749.12 CRK42064.1 - 0.3 11.6 0.2 0.3 11.6 0.2 2.6 3 1 0 3 3 3 0 Protein of unknown function (DUF1218) SLATT_5 PF18160.1 CRK42064.1 - 6.3 6.1 5.8 1.8 7.9 1.1 1.9 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 Cu_bind_like PF02298.17 CRK42066.1 - 0.0041 17.1 4.8 0.54 10.3 0.2 3.2 2 2 0 2 2 2 2 Plastocyanin-like domain Cupredoxin_1 PF13473.6 CRK42066.1 - 0.016 15.3 0.6 3.6 7.7 0.0 3.2 3 0 0 3 3 3 0 Cupredoxin-like domain RBD-FIP PF09457.10 CRK42066.1 - 0.2 11.6 0.4 0.43 10.5 0.4 1.5 1 0 0 1 1 1 0 FIP domain Gpr1_Fun34_YaaH PF01184.19 CRK42068.1 - 7e-18 65.0 18.0 1.3e-17 64.1 17.7 1.4 1 1 1 2 2 2 1 GPR1/FUN34/yaaH family CoA_binding_2 PF13380.6 CRK42070.1 - 8.3e-28 97.2 0.1 1.1e-27 96.8 0.1 1.1 1 0 0 1 1 1 1 CoA binding domain DUF853 PF05872.12 CRK42070.1 - 0.072 11.7 0.0 0.087 11.4 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) BIR PF00653.21 CRK42072.1 - 1.3e-44 150.7 4.3 5e-22 78.3 0.1 2.5 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain Biotin_carb_N PF00289.22 CRK42072.1 - 0.048 14.2 0.0 0.15 12.6 0.0 1.8 1 0 0 1 1 1 0 Biotin carboxylase, N-terminal domain HET PF06985.11 CRK42074.1 - 6.3e-20 72.0 0.1 1.2e-19 71.1 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) F-box-like PF12937.7 CRK42074.1 - 1.2e-06 28.3 1.1 3.8e-06 26.7 0.4 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CRK42074.1 - 0.0015 18.3 0.1 0.004 17.0 0.1 1.7 1 0 0 1 1 1 1 F-box domain Ferritin_2 PF13668.6 CRK42076.1 - 9.6e-45 152.1 1.9 1.4e-44 151.6 1.9 1.2 1 0 0 1 1 1 1 Ferritin-like domain adh_short PF00106.25 CRK42078.1 - 7.4e-15 54.9 0.1 3.7e-14 52.6 0.1 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK42078.1 - 5.9e-11 42.4 0.6 3.9e-10 39.7 0.6 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DHO_dh PF01180.21 CRK42080.1 - 1.1e-67 228.3 0.1 3.1e-55 187.5 0.0 2.2 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase Mpv17_PMP22 PF04117.12 CRK42080.1 - 6.2e-18 64.8 2.3 6.9e-18 64.6 0.2 2.3 2 0 0 2 2 2 1 Mpv17 / PMP22 family PEP_hydrolase PF09370.10 CRK42080.1 - 0.018 14.2 0.1 0.035 13.3 0.1 1.5 1 0 0 1 1 1 0 Phosphoenolpyruvate hydrolase-like PcrB PF01884.17 CRK42080.1 - 0.052 13.0 2.0 0.16 11.4 0.1 2.1 2 0 0 2 2 2 0 PcrB family adh_short PF00106.25 CRK42086.1 - 2.3e-22 79.4 0.1 3e-21 75.8 0.1 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK42086.1 - 3.8e-18 65.9 0.1 8.2e-17 61.5 0.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK42086.1 - 4.9e-05 23.3 1.4 0.00014 21.9 1.4 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 CRK42086.1 - 0.0046 16.4 0.9 0.033 13.6 0.9 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family CFEM PF05730.11 CRK42089.1 - 9.5e-12 44.8 12.3 1.6e-11 44.1 12.3 1.4 1 0 0 1 1 1 1 CFEM domain AMP-binding PF00501.28 CRK42092.1 - 1.4e-71 241.3 0.1 3.9e-71 239.9 0.1 1.7 2 0 0 2 2 2 1 AMP-binding enzyme Condensation PF00668.20 CRK42092.1 - 3e-66 224.0 0.0 4.4e-66 223.4 0.0 1.2 1 0 0 1 1 1 1 Condensation domain ketoacyl-synt PF00109.26 CRK42092.1 - 1.1e-60 205.4 0.1 6.6e-60 202.8 0.1 2.1 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 CRK42092.1 - 1.6e-50 171.5 0.0 1e-49 168.9 0.0 2.2 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 CRK42092.1 - 7.1e-39 133.8 0.0 1.2e-38 133.0 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 CRK42092.1 - 7.1e-39 134.2 0.0 1.3e-38 133.3 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 CRK42092.1 - 3.3e-31 107.7 0.2 2e-30 105.2 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.12 CRK42092.1 - 6.2e-31 107.5 0.0 2.3e-30 105.6 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein Methyltransf_12 PF08242.12 CRK42092.1 - 4.2e-18 65.9 0.0 1.3e-17 64.3 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 CRK42092.1 - 3.1e-16 59.5 2.5 1.4e-09 38.1 0.0 3.6 3 0 0 3 3 3 2 Phosphopantetheine attachment site adh_short PF00106.25 CRK42092.1 - 1.2e-13 50.9 0.0 2.7e-11 43.3 0.0 2.9 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_23 PF13489.6 CRK42092.1 - 2.2e-13 50.3 0.0 5.5e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 CRK42092.1 - 2.4e-12 47.3 0.0 6.5e-12 45.9 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_25 PF13649.6 CRK42092.1 - 4.6e-12 46.5 0.0 4.5e-11 43.3 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CRK42092.1 - 9.4e-12 45.4 0.0 6e-11 42.8 0.0 2.5 2 0 0 2 2 1 1 Methyltransferase domain Epimerase PF01370.21 CRK42092.1 - 6.5e-11 42.2 0.0 4.3e-06 26.4 0.0 2.6 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Methyltransf_31 PF13847.6 CRK42092.1 - 3.3e-10 40.0 0.0 7.6e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CRK42092.1 - 1.3e-06 27.9 0.0 3.7e-06 26.4 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family adh_short_C2 PF13561.6 CRK42092.1 - 3.2e-05 23.6 0.0 0.00014 21.5 0.0 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Thiolase_N PF00108.23 CRK42092.1 - 0.00025 20.5 0.0 0.00055 19.4 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain 3Beta_HSD PF01073.19 CRK42092.1 - 0.005 15.9 0.0 0.058 12.4 0.0 2.2 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family ACP_syn_III PF08545.10 CRK42092.1 - 0.0097 15.7 0.7 0.17 11.8 0.3 2.8 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GDP_Man_Dehyd PF16363.5 CRK42092.1 - 0.012 15.0 0.0 0.24 10.7 0.0 2.2 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Methyltransf_16 PF10294.9 CRK42092.1 - 0.014 15.1 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 Lysine methyltransferase NmrA PF05368.13 CRK42092.1 - 0.016 14.8 0.1 0.1 12.1 0.0 2.2 2 0 0 2 2 2 0 NmrA-like family NAD_binding_10 PF13460.6 CRK42092.1 - 0.11 12.4 0.0 0.59 10.0 0.0 2.3 2 0 0 2 2 2 0 NAD(P)H-binding Abhydrolase_6 PF12697.7 CRK42096.1 - 3.8e-05 24.4 2.7 5e-05 24.0 2.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CRK42096.1 - 0.00042 20.0 0.1 0.0014 18.3 0.2 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF1057 PF06342.12 CRK42096.1 - 0.0048 16.0 0.0 0.0066 15.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_4 PF08386.10 CRK42096.1 - 0.17 12.0 0.0 0.3 11.2 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein Abhydrolase_6 PF12697.7 CRK42098.1 - 5.9e-05 23.8 0.1 0.00011 22.9 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.12 CRK42098.1 - 0.00038 19.2 0.0 0.00074 18.3 0.0 1.4 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) DLH PF01738.18 CRK42098.1 - 0.0092 15.6 0.0 0.025 14.1 0.0 1.6 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 CRK42098.1 - 0.015 14.8 0.0 0.027 13.9 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Esterase PF00756.20 CRK42098.1 - 0.093 12.4 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Putative esterase ADH_zinc_N PF00107.26 CRK42100.1 - 8.2e-08 32.3 0.0 1.7e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CRK42100.1 - 2.2e-07 30.8 0.0 1e-06 28.6 0.0 2.1 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Zn_clus PF00172.18 CRK42104.1 - 1.3e-06 28.4 10.1 2.2e-06 27.7 10.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 CRK42106.1 - 2.2e-41 142.0 36.2 2.2e-41 142.0 36.2 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 CRK42106.1 - 1e-20 73.7 17.5 1.7e-20 73.0 17.5 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 CRK42106.1 - 1.6e-15 57.0 7.1 1.6e-15 57.0 7.1 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter DUF1304 PF06993.12 CRK42106.1 - 0.93 9.5 5.9 1.4 8.9 0.4 3.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1304) Clr5 PF14420.6 CRK42107.1 - 6.7e-16 58.3 0.0 1.6e-15 57.0 0.0 1.7 1 0 0 1 1 1 1 Clr5 domain TPR_12 PF13424.6 CRK42107.1 - 1.2 9.4 3.9 3.6 7.9 0.1 2.7 2 1 0 3 3 3 0 Tetratricopeptide repeat DUF3456 PF11938.8 CRK42109.1 - 0.17 12.4 0.0 0.55 10.7 0.0 1.8 2 0 0 2 2 2 0 TLR4 regulator and MIR-interacting MSAP Nuf2 PF03800.14 CRK42111.1 - 1e-41 142.3 0.0 2.6e-41 141.0 0.0 1.7 1 0 0 1 1 1 1 Nuf2 family DHR10 PF18595.1 CRK42111.1 - 7.1e-35 119.6 15.6 7.1e-35 119.6 15.6 4.0 3 1 0 3 3 3 1 Designed helical repeat protein 10 domain Adaptin_N PF01602.20 CRK42114.1 - 3.3e-85 286.6 0.0 1.7e-68 231.5 0.0 2.2 1 1 1 2 2 2 2 Adaptin N terminal region RTA1 PF04479.13 CRK42114.1 - 1.3e-80 269.9 3.0 6.2e-64 215.4 1.3 2.3 2 0 0 2 2 2 2 RTA1 like protein Fungal_trans PF04082.18 CRK42114.1 - 3.6e-13 49.2 0.0 7.5e-13 48.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK42114.1 - 7.2e-09 35.6 8.9 1.4e-08 34.7 8.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cnd1 PF12717.7 CRK42114.1 - 2.9e-06 27.4 0.1 1.1e-05 25.6 0.0 2.0 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CRK42114.1 - 0.00017 21.9 9.5 0.64 10.4 0.4 5.0 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.22 CRK42114.1 - 0.41 11.0 2.9 17 6.0 0.0 4.5 4 0 0 4 4 4 0 HEAT repeat NOA36 PF06524.12 CRK42114.1 - 2.4 7.4 18.3 5.2 6.3 18.3 1.5 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 CRK42114.1 - 3.1 5.9 18.3 5 5.2 18.3 1.2 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.12 CRK42114.1 - 7.2 6.3 16.7 13 5.4 16.7 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein ADH_zinc_N_2 PF13602.6 CRK42117.1 - 3.8e-19 70.0 0.0 7.2e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 CRK42117.1 - 8.7e-12 45.1 0.4 2.4e-11 43.7 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Semialdhyde_dh PF01118.24 CRK42117.1 - 0.00012 22.5 0.2 0.00051 20.5 0.2 1.9 1 1 1 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain ADH_N PF08240.12 CRK42117.1 - 0.00064 19.6 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Epimerase PF01370.21 CRK42117.1 - 0.023 14.2 0.1 0.056 12.9 0.1 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 CRK42117.1 - 0.049 12.9 0.7 0.29 10.4 0.7 2.0 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DapB_N PF01113.20 CRK42117.1 - 0.087 12.9 0.2 0.14 12.3 0.2 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Cupin_2 PF07883.11 CRK42119.1 - 2.3e-10 40.1 0.5 4.3e-10 39.2 0.5 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 CRK42119.1 - 6.8e-05 22.5 0.1 7.8e-05 22.3 0.1 1.2 1 0 0 1 1 1 1 Cupin NAD_binding_2 PF03446.15 CRK42121.1 - 1.5e-35 122.7 0.0 2.5e-35 122.0 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 CRK42121.1 - 4.3e-29 101.2 0.0 8e-29 100.4 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 CRK42121.1 - 0.00017 22.1 0.0 0.00042 20.9 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent OCD_Mu_crystall PF02423.15 CRK42121.1 - 0.00073 18.6 0.1 0.0012 17.8 0.1 1.3 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Ldh_1_N PF00056.23 CRK42121.1 - 0.0045 17.1 0.0 0.011 15.8 0.0 1.7 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 CRK42121.1 - 0.077 12.9 1.2 1.3 8.9 1.2 2.4 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 CRK42121.1 - 0.086 13.7 0.0 0.19 12.5 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold B3_4 PF03483.17 CRK42121.1 - 0.16 11.6 0.1 0.26 10.9 0.1 1.2 1 0 0 1 1 1 0 B3/4 domain Rho_GDI PF02115.17 CRK42123.1 - 5.8e-28 98.0 9.0 9.2e-22 77.7 0.1 3.8 3 1 1 4 4 4 2 RHO protein GDP dissociation inhibitor MCU PF04678.13 CRK42123.1 - 1.4 9.0 5.2 2.5 8.2 5.2 1.4 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Presenilin PF01080.17 CRK42123.1 - 5.6 5.6 5.6 8.1 5.1 5.6 1.2 1 0 0 1 1 1 0 Presenilin Metallophos PF00149.28 CRK42125.1 - 1.1e-35 124.1 0.6 1.4e-35 123.7 0.6 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Egh16-like PF11327.8 CRK42129.1 - 2.3e-55 187.9 4.1 1.2e-52 179.0 4.1 2.2 1 1 0 1 1 1 1 Egh16-like virulence factor AAA_12 PF13087.6 CRK42132.1 - 6.4e-18 65.1 0.0 8.4e-18 64.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 CRK42132.1 - 0.02 14.7 0.0 0.047 13.5 0.0 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain MtrB PF05440.12 CRK42132.1 - 0.12 12.8 0.0 0.2 12.1 0.0 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase subunit B Transp_cyt_pur PF02133.15 CRK42133.1 - 2e-152 508.1 42.4 2.3e-152 507.8 42.4 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin vMSA PF00695.19 CRK42136.1 - 0.13 11.3 0.1 0.15 11.1 0.1 1.0 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus U-box PF04564.15 CRK42139.1 - 1.7e-17 63.3 0.0 5.3e-17 61.8 0.0 1.9 1 0 0 1 1 1 1 U-box domain Homeobox_KN PF05920.11 CRK42139.1 - 5.1e-10 39.1 0.1 2e-09 37.2 0.2 2.1 2 0 0 2 2 2 1 Homeobox KN domain HTH_Tnp_Tc5 PF03221.16 CRK42139.1 - 5e-05 23.2 0.0 0.0014 18.7 0.0 2.9 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain Homeodomain PF00046.29 CRK42139.1 - 0.0021 17.9 0.1 0.0069 16.2 0.1 1.9 1 0 0 1 1 1 1 Homeodomain TPR_2 PF07719.17 CRK42139.1 - 0.0032 17.4 7.6 0.3 11.3 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat CHIP_TPR_N PF18391.1 CRK42139.1 - 0.012 16.3 8.6 0.093 13.5 7.0 2.5 2 0 0 2 2 2 0 CHIP N-terminal tetratricopeptide repeat domain ImpA_N PF06812.12 CRK42139.1 - 0.059 13.5 1.2 0.21 11.7 0.0 2.4 2 0 0 2 2 2 0 ImpA, N-terminal, type VI secretion system ANAPC3 PF12895.7 CRK42139.1 - 0.074 13.3 1.8 0.17 12.1 1.8 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 CRK42139.1 - 0.085 13.7 2.2 4.2 8.5 0.2 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 CRK42139.1 - 0.13 13.0 3.4 0.71 10.6 3.4 2.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 CRK42139.1 - 0.22 11.4 5.0 3.3 7.7 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 CRK42139.1 - 0.26 11.0 3.6 1.9 8.3 0.4 2.7 2 0 0 2 2 2 0 TPR repeat zf-C2H2_4 PF13894.6 CRK42139.1 - 0.29 12.1 19.0 0.084 13.8 1.4 4.5 5 0 0 5 5 4 0 C2H2-type zinc finger TPR_19 PF14559.6 CRK42139.1 - 0.37 11.3 3.5 4.8 7.8 3.8 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat APH PF01636.23 CRK42141.1 - 0.00071 19.6 1.5 0.004 17.1 1.5 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Glyco_hydro_26 PF02156.15 CRK42141.1 - 0.045 13.2 0.6 0.069 12.6 0.6 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 26 DUF5436 PF17504.2 CRK42141.1 - 0.061 13.6 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5436) DIE2_ALG10 PF04922.12 CRK42143.1 - 3.1e-87 293.4 2.4 2.7e-54 185.0 0.2 2.2 2 0 0 2 2 2 2 DIE2/ALG10 family QCR10 PF09796.9 CRK42146.1 - 3.8e-23 81.3 0.2 5.5e-23 80.8 0.2 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Phage_holin_8 PF16931.5 CRK42146.1 - 0.021 14.8 0.3 0.032 14.2 0.3 1.2 1 0 0 1 1 1 0 Putative phage holin Med4 PF10018.9 CRK42148.1 - 9.6e-32 110.2 0.0 1.4e-31 109.7 0.0 1.3 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 ZnuA PF01297.17 CRK42148.1 - 0.024 14.0 0.2 0.33 10.3 0.1 2.3 2 1 1 3 3 3 0 Zinc-uptake complex component A periplasmic PspA_IM30 PF04012.12 CRK42148.1 - 0.05 13.2 2.6 0.068 12.7 2.6 1.1 1 0 0 1 1 1 0 PspA/IM30 family PCRF PF03462.18 CRK42148.1 - 0.12 12.3 1.1 0.16 11.8 1.1 1.1 1 0 0 1 1 1 0 PCRF domain DIE2_ALG10 PF04922.12 CRK42150.1 - 2.8e-97 326.5 6.2 9.8e-97 324.7 6.2 1.8 1 1 0 1 1 1 1 DIE2/ALG10 family QCR10 PF09796.9 CRK42152.1 - 3.8e-23 81.3 0.2 5.5e-23 80.8 0.2 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Phage_holin_8 PF16931.5 CRK42152.1 - 0.021 14.8 0.3 0.032 14.2 0.3 1.2 1 0 0 1 1 1 0 Putative phage holin Med4 PF10018.9 CRK42155.1 - 1e-33 116.6 0.1 1.7e-33 115.9 0.1 1.3 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 ZnuA PF01297.17 CRK42155.1 - 0.045 13.2 0.2 0.41 10.0 0.1 2.2 2 1 1 3 3 3 0 Zinc-uptake complex component A periplasmic UDPG_MGDP_dh_C PF03720.15 CRK42155.1 - 0.14 12.6 0.1 0.48 10.9 0.0 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain EMP70 PF02990.16 CRK42157.1 - 3.7e-202 672.6 4.5 5.2e-202 672.1 4.5 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 PIRT PF15099.6 CRK42157.1 - 2.5 7.7 6.7 0.9 9.1 2.7 2.2 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family Sas10_Utp3 PF04000.15 CRK42159.1 - 5.5e-17 62.2 0.6 5.5e-17 62.2 0.6 2.3 2 0 0 2 2 2 1 Sas10/Utp3/C1D family RXT2_N PF08595.11 CRK42159.1 - 0.025 14.6 2.9 0.055 13.5 2.9 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal DNA_pol_phi PF04931.13 CRK42159.1 - 0.19 9.8 9.6 0.28 9.2 9.6 1.3 1 0 0 1 1 1 0 DNA polymerase phi CCDC106 PF15794.5 CRK42159.1 - 1.1 8.9 6.9 0.11 12.2 1.4 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 CDC45 PF02724.14 CRK42159.1 - 2 6.6 9.3 2.7 6.2 9.3 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF4611 PF15387.6 CRK42159.1 - 2.1 8.6 12.0 0.25 11.6 7.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Striatin PF08232.12 CRK42159.1 - 5.8 7.5 9.3 24 5.5 9.3 2.2 1 1 0 1 1 1 0 Striatin family NOA36 PF06524.12 CRK42159.1 - 6.4 6.0 14.2 12 5.1 14.2 1.3 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 CRK42159.1 - 7.8 7.0 14.2 0.31 11.5 8.5 1.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain FMO-like PF00743.19 CRK42161.1 - 1.6e-16 59.8 0.0 7.8e-16 57.6 0.0 1.9 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 CRK42161.1 - 4.3e-16 59.0 0.0 5.2e-15 55.5 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CRK42161.1 - 5.5e-13 48.8 0.0 2.2e-10 40.3 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CRK42161.1 - 7.2e-11 41.8 0.0 1.2e-08 34.5 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 CRK42161.1 - 3e-06 27.4 0.4 1.7e-05 24.9 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 CRK42161.1 - 4.8e-05 23.8 1.6 0.15 12.6 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 CRK42161.1 - 0.00028 20.6 5.6 0.0024 17.5 5.6 2.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 CRK42161.1 - 0.00031 20.1 1.0 0.021 14.1 0.2 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 CRK42161.1 - 0.0042 17.1 0.5 0.16 11.9 0.1 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 CRK42161.1 - 0.0092 15.1 1.0 0.0092 15.1 1.0 1.5 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 CRK42161.1 - 0.013 14.9 0.0 0.047 13.0 0.0 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase Shikimate_DH PF01488.20 CRK42161.1 - 0.015 15.3 0.0 4.1 7.5 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 CRK42161.1 - 0.023 14.6 1.9 0.05 13.5 1.7 1.6 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 CRK42161.1 - 0.023 13.4 1.2 0.12 11.1 0.4 2.2 3 0 0 3 3 3 0 HI0933-like protein NAD_Gly3P_dh_N PF01210.23 CRK42161.1 - 0.11 12.5 0.2 0.46 10.5 0.1 2.1 3 0 0 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GIDA PF01134.22 CRK42161.1 - 0.33 10.0 2.8 0.28 10.2 0.6 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A p450 PF00067.22 CRK42162.1 - 6.6e-90 302.1 0.0 7.9e-90 301.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 VARLMGL PF14383.6 CRK42162.1 - 0.13 11.8 0.1 0.13 11.8 0.1 2.0 2 0 0 2 2 2 0 DUF761-associated sequence motif Fungal_trans PF04082.18 CRK42164.1 - 9.8e-08 31.3 0.0 1.9e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK42164.1 - 0.017 15.3 8.9 0.046 13.8 8.9 1.8 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MGC-24 PF05283.11 CRK42164.1 - 3.2 8.2 12.2 7.7 7.0 12.2 1.6 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin IBN_N PF03810.19 CRK42166.1 - 1.3e-09 37.8 0.0 4.1e-09 36.2 0.0 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain CAS_CSE1 PF03378.15 CRK42166.1 - 0.0049 15.4 0.0 0.0083 14.7 0.0 1.3 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus RINGv PF12906.7 CRK42168.1 - 2e-05 24.6 8.4 3.2e-05 24.0 8.4 1.3 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 CRK42168.1 - 0.00067 19.9 7.9 0.0011 19.3 7.9 1.3 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 CRK42168.1 - 0.00098 19.3 3.5 0.0017 18.5 3.5 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain PHD PF00628.29 CRK42168.1 - 0.057 13.3 8.5 0.088 12.7 8.5 1.3 1 0 0 1 1 1 0 PHD-finger zf-RING_4 PF14570.6 CRK42168.1 - 0.12 12.2 6.7 0.21 11.4 6.7 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 CRK42168.1 - 1.1 9.2 4.6 2 8.3 4.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CRK42168.1 - 7.2 6.6 6.7 11 6.0 6.7 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) HEAT PF02985.22 CRK42172.1 - 0.00016 21.6 0.0 0.58 10.6 0.0 2.6 2 0 0 2 2 2 2 HEAT repeat HEAT_2 PF13646.6 CRK42172.1 - 0.0022 18.3 0.0 0.011 16.1 0.0 1.8 1 1 1 2 2 2 2 HEAT repeats BRCA-2_OB3 PF09104.10 CRK42172.1 - 0.099 12.3 0.2 0.25 11.0 0.0 1.7 2 0 0 2 2 2 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 LisH_TPL PF17814.1 CRK42172.1 - 0.3 10.8 1.3 0.95 9.2 0.1 2.2 2 0 0 2 2 2 0 LisH-like dimerisation domain DUF3435 PF11917.8 CRK42179.1 - 4.8e-28 98.2 0.0 5.9e-28 97.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Ribosomal_L21e PF01157.18 CRK42184.1 - 1.8e-46 156.1 5.0 3.1e-46 155.4 5.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L21e I_LWEQ PF01608.17 CRK42184.1 - 6.4e-45 153.1 8.1 9.3e-45 152.6 8.1 1.2 1 0 0 1 1 1 1 I/LWEQ domain Focal_AT PF03623.13 CRK42184.1 - 0.03 14.3 1.4 0.24 11.4 0.1 2.5 2 1 1 3 3 3 0 Focal adhesion targeting region Asp PF00026.23 CRK42188.1 - 3.4e-14 53.0 0.0 4.1e-14 52.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 CRK42188.1 - 0.0012 18.6 0.0 0.0021 17.8 0.0 1.4 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal TBCA PF02970.16 CRK42190.1 - 3.1e-05 24.2 0.1 4e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor A ABC_tran PF00005.27 CRK42193.1 - 1.6e-19 70.7 0.3 1.1e-13 51.8 0.0 2.3 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CRK42193.1 - 6.4e-08 32.8 0.5 0.0036 17.2 0.0 2.7 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CRK42193.1 - 2.5e-05 23.8 0.2 0.19 11.2 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 CRK42193.1 - 2.6e-05 24.2 0.0 4.8e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 CRK42193.1 - 0.0002 21.4 0.1 0.00064 19.8 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 CRK42193.1 - 0.00049 20.2 0.0 0.0012 19.0 0.0 1.6 1 1 0 1 1 1 1 Dynamin family AAA_23 PF13476.6 CRK42193.1 - 0.00064 20.3 0.5 0.0013 19.2 0.2 1.5 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 CRK42193.1 - 0.0016 18.1 0.0 0.0029 17.3 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_28 PF13521.6 CRK42193.1 - 0.011 16.0 0.0 0.019 15.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 CRK42193.1 - 0.014 15.2 0.0 0.031 14.0 0.0 1.5 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 CRK42193.1 - 0.026 14.9 0.0 0.041 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain MeaB PF03308.16 CRK42193.1 - 0.041 12.9 0.1 0.069 12.1 0.1 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RNA_helicase PF00910.22 CRK42193.1 - 0.13 12.7 0.0 0.23 11.9 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.6 CRK42193.1 - 0.15 12.4 0.0 0.35 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 CRK42193.1 - 0.16 11.6 0.0 0.58 9.8 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain IIGP PF05049.13 CRK42193.1 - 0.17 10.9 0.0 0.28 10.2 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) DUF87 PF01935.17 CRK42193.1 - 0.17 11.9 0.0 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain Aa_trans PF01490.18 CRK42194.1 - 7e-29 100.8 18.1 7.8e-29 100.6 18.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Clc-like PF07062.12 CRK42194.1 - 0.05 13.1 0.1 0.05 13.1 0.1 2.3 1 1 2 3 3 3 0 Clc-like Chorismate_synt PF01264.21 CRK42203.1 - 5.9e-63 212.6 0.1 6.6e-63 212.4 0.1 1.0 1 0 0 1 1 1 1 Chorismate synthase DUF3224 PF11528.8 CRK42203.1 - 0.0014 18.5 0.0 0.0019 18.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3224) Methyltransf_25 PF13649.6 CRK42218.1 - 1.9e-09 38.1 0.0 3.2e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK42218.1 - 1.7e-07 31.2 0.0 3.2e-07 30.3 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CRK42218.1 - 2.8e-07 30.5 0.0 4.5e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CRK42218.1 - 3.6e-07 30.7 0.0 5.8e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 CRK42218.1 - 6.6e-07 29.4 0.0 7.3e-06 26.1 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain MTS PF05175.14 CRK42218.1 - 6.9e-06 25.7 0.0 9.5e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 CRK42218.1 - 4.1e-05 24.2 0.5 0.0001 23.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 CRK42218.1 - 4.2e-05 23.1 0.0 5.8e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 CRK42218.1 - 4.7e-05 22.8 0.0 5.7e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase DREV PF05219.12 CRK42218.1 - 0.00044 19.4 0.0 0.00051 19.2 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase GidB PF02527.15 CRK42218.1 - 0.001 18.4 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G UPF0146 PF03686.13 CRK42218.1 - 0.0015 18.4 0.0 0.0019 18.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0146) Methyltransf_18 PF12847.7 CRK42218.1 - 0.0026 17.7 0.0 0.0044 17.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 CRK42218.1 - 0.0051 16.6 0.0 0.006 16.3 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) adh_short PF00106.25 CRK42218.1 - 0.029 13.8 0.0 0.039 13.4 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase TMV_coat PF00721.21 CRK42218.1 - 0.045 13.6 1.0 0.12 12.2 0.0 1.8 1 1 1 2 2 2 0 Virus coat protein (TMV like) TehB PF03848.14 CRK42218.1 - 0.046 13.1 0.0 0.069 12.6 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB MetW PF07021.12 CRK42218.1 - 0.053 13.1 0.0 0.075 12.6 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW MethyltransfD12 PF02086.15 CRK42218.1 - 0.1 12.3 0.0 0.2 11.3 0.0 1.5 2 0 0 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase TPMT PF05724.11 CRK42218.1 - 0.18 11.4 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) CorA PF01544.18 CRK42219.1 - 4.6e-10 39.3 0.0 7.9e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein MFS_1 PF07690.16 CRK42221.1 - 9.8e-38 130.0 23.7 9.8e-38 130.0 23.7 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Chromate_transp PF02417.15 CRK42223.1 - 1.1e-55 188.1 37.8 9.4e-34 116.8 13.7 2.6 3 0 0 3 3 3 2 Chromate transporter DUF3328 PF11807.8 CRK42223.1 - 1.6 8.4 2.8 2 8.1 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3328) DUF1918 PF08940.11 CRK42224.1 - 0.25 11.0 1.5 0.72 9.5 1.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) NACHT PF05729.12 CRK42226.1 - 7.9e-09 35.6 0.0 2.4e-08 34.1 0.0 1.8 1 0 0 1 1 1 1 NACHT domain HET PF06985.11 CRK42226.1 - 9.7e-08 32.5 0.0 2.9e-07 31.0 0.0 1.9 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AAA_16 PF13191.6 CRK42226.1 - 0.049 14.0 6.4 0.15 12.5 0.0 3.9 4 0 0 4 4 4 0 AAA ATPase domain DUF3632 PF12311.8 CRK42226.1 - 0.059 13.8 0.2 14 6.0 0.3 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3632) Pyridoxal_deC PF00282.19 CRK42227.1 - 1.4e-73 247.8 0.0 1.9e-73 247.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 CRK42227.1 - 0.00019 20.5 0.0 0.00032 19.8 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 CRK42227.1 - 0.00048 19.5 0.0 0.00068 19.0 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Ras PF00071.22 CRK42229.1 - 6.1e-39 133.2 0.0 2.8e-25 88.8 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 CRK42229.1 - 1.5e-11 44.5 0.1 3.2e-11 43.5 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 CRK42229.1 - 0.0027 17.8 0.0 0.0044 17.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 CRK42229.1 - 0.01 15.3 0.0 0.026 14.0 0.0 1.6 2 0 0 2 2 2 0 ADP-ribosylation factor family PRK PF00485.18 CRK42229.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family GTP_EFTU PF00009.27 CRK42229.1 - 0.16 11.5 0.2 1.4 8.4 0.1 2.3 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain SR-25 PF10500.9 CRK42232.1 - 0.00062 19.4 6.2 0.00064 19.4 6.2 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DDE_Tnp_IS1595 PF12762.7 CRK42232.1 - 0.034 14.2 0.4 0.036 14.1 0.4 1.1 1 0 0 1 1 1 0 ISXO2-like transposase domain AP3D1 PF06375.11 CRK42232.1 - 1.8 8.8 12.0 2.2 8.5 12.0 1.1 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 LapA_dom PF06305.11 CRK42232.1 - 2.5 8.0 3.8 3.3 7.6 3.8 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain UCH PF00443.29 CRK42234.1 - 7e-40 137.1 0.0 1.8e-20 73.5 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.6 CRK42234.1 - 3e-18 65.5 0.1 3.8e-10 39.5 0.1 3.1 2 0 0 2 2 2 2 A repeated domain in UCH-protein UCH_1 PF13423.6 CRK42234.1 - 2.9e-06 27.1 0.3 0.00095 18.8 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase PUB PF09409.10 CRK42234.1 - 0.0029 17.5 0.0 0.0084 16.0 0.0 1.7 1 0 0 1 1 1 1 PUB domain Tim17 PF02466.19 CRK42236.1 - 4.9e-09 36.6 5.2 7.1e-09 36.0 5.2 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family MutS_V PF00488.21 CRK42237.1 - 3.3e-83 278.3 0.7 5.4e-83 277.7 0.7 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 CRK42237.1 - 2.3e-36 125.8 0.6 2.3e-36 125.8 0.6 2.2 3 0 0 3 3 3 1 MutS domain III MutS_II PF05188.17 CRK42237.1 - 1.2e-23 83.8 1.9 1.2e-22 80.7 0.1 3.2 3 0 0 3 3 3 1 MutS domain II MutS_I PF01624.20 CRK42237.1 - 2.7e-20 72.7 0.1 1.9e-19 69.9 0.0 2.4 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.18 CRK42237.1 - 6.4e-18 64.9 4.4 1.1e-17 64.2 1.8 2.7 3 0 0 3 3 3 1 MutS family domain IV AAA_27 PF13514.6 CRK42237.1 - 0.053 13.1 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain tRNA_m1G_MT PF01746.21 CRK42238.1 - 7.2e-31 107.4 0.0 5.2e-23 81.8 0.0 2.2 2 0 0 2 2 2 2 tRNA (Guanine-1)-methyltransferase PNPase_C PF12111.8 CRK42238.1 - 0.25 10.8 1.1 0.89 9.0 1.1 1.9 1 0 0 1 1 1 0 Polyribonucleotide phosphorylase C terminal DNA_primase_S PF01896.19 CRK42239.1 - 6.5e-64 215.2 0.2 9.1e-64 214.7 0.2 1.2 1 0 0 1 1 1 1 DNA primase small subunit UCH PF00443.29 CRK42240.1 - 4.6e-39 134.5 0.0 7.8e-39 133.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.6 CRK42240.1 - 1.7e-18 66.3 0.1 1.2e-10 41.2 0.1 2.9 2 0 0 2 2 2 2 A repeated domain in UCH-protein UCH_1 PF13423.6 CRK42240.1 - 6.3e-06 26.0 0.2 0.0022 17.7 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase PUB PF09409.10 CRK42240.1 - 0.0022 17.9 0.0 0.0078 16.1 0.0 1.9 2 0 0 2 2 2 1 PUB domain Tim17 PF02466.19 CRK42241.1 - 8.3e-09 35.8 5.9 1.2e-08 35.3 5.9 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family MutS_III PF05192.18 CRK42242.1 - 5.9e-36 124.5 1.8 6.2e-36 124.4 0.4 1.8 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.17 CRK42242.1 - 8.8e-24 84.3 1.8 1.2e-22 80.7 0.1 3.1 3 0 0 3 3 3 1 MutS domain II MutS_I PF01624.20 CRK42242.1 - 3.7e-20 72.3 0.1 1.3e-19 70.5 0.0 2.0 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.18 CRK42242.1 - 1.1e-17 64.2 5.2 1.5e-17 63.7 2.0 2.8 3 0 0 3 3 3 1 MutS family domain IV MutS_V PF00488.21 CRK42242.1 - 0.0089 16.1 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 MutS domain V SUR7 PF06687.12 CRK42242.1 - 0.14 11.7 0.0 0.42 10.2 0.0 1.7 2 0 0 2 2 2 0 SUR7/PalI family tRNA_m1G_MT PF01746.21 CRK42243.1 - 8.2e-31 107.2 0.0 6.4e-23 81.5 0.0 2.2 2 0 0 2 2 2 2 tRNA (Guanine-1)-methyltransferase PNPase_C PF12111.8 CRK42243.1 - 0.28 10.6 1.1 0.9 9.0 1.1 1.9 1 0 0 1 1 1 0 Polyribonucleotide phosphorylase C terminal DNA_primase_S PF01896.19 CRK42245.1 - 9.6e-64 214.7 0.1 1.3e-63 214.2 0.1 1.2 1 0 0 1 1 1 1 DNA primase small subunit HSF_DNA-bind PF00447.17 CRK42248.1 - 8.6e-31 106.4 2.3 1.6e-30 105.6 2.3 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.24 CRK42248.1 - 2.2e-21 76.1 0.0 4.5e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain TMCO5 PF14992.6 CRK42248.1 - 0.0077 15.8 2.2 0.012 15.2 2.2 1.2 1 0 0 1 1 1 1 TMCO5 family Fungal_TACC PF12709.7 CRK42248.1 - 0.03 14.7 1.6 0.074 13.5 1.6 1.7 1 1 0 1 1 1 0 Fungal Transforming acidic coiled-coil (TACC) proteins YabA PF06156.13 CRK42248.1 - 0.047 14.3 1.7 0.11 13.1 1.7 1.6 1 0 0 1 1 1 0 Initiation control protein YabA bZIP_1 PF00170.21 CRK42248.1 - 0.065 13.3 0.4 0.13 12.4 0.4 1.5 1 0 0 1 1 1 0 bZIP transcription factor DivIC PF04977.15 CRK42248.1 - 0.091 12.5 3.1 0.19 11.5 3.1 1.5 1 0 0 1 1 1 0 Septum formation initiator SlyX PF04102.12 CRK42248.1 - 0.82 10.3 6.9 5 7.8 6.9 2.4 1 1 0 1 1 1 0 SlyX W2 PF02020.18 CRK42250.1 - 1.5e-20 73.1 0.5 3.6e-20 71.9 0.5 1.6 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 CRK42250.1 - 4.3e-05 23.1 12.7 0.0098 15.6 5.0 3.0 1 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 CRK42250.1 - 0.0014 18.3 0.0 0.0023 17.5 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase DUF4954 PF16314.5 CRK42250.1 - 0.0025 16.0 2.9 0.0038 15.5 2.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 CRK42250.1 - 0.0031 17.2 8.6 0.0057 16.4 3.8 2.8 2 1 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase NTP_transf_3 PF12804.7 CRK42250.1 - 0.0092 16.3 0.6 0.049 14.0 0.0 2.5 3 1 0 3 3 3 1 MobA-like NTP transferase domain Fucokinase PF07959.12 CRK42250.1 - 0.012 14.5 0.6 0.033 13.1 0.6 1.7 1 1 0 1 1 1 0 L-fucokinase HSF_DNA-bind PF00447.17 CRK42252.1 - 8.7e-31 106.4 2.3 1.6e-30 105.6 2.3 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.24 CRK42252.1 - 2.2e-21 76.1 0.0 4.5e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain TMCO5 PF14992.6 CRK42252.1 - 0.0054 16.3 1.7 0.0085 15.7 1.7 1.2 1 0 0 1 1 1 1 TMCO5 family Fungal_TACC PF12709.7 CRK42252.1 - 0.031 14.7 1.6 0.074 13.5 1.6 1.7 1 1 0 1 1 1 0 Fungal Transforming acidic coiled-coil (TACC) proteins YabA PF06156.13 CRK42252.1 - 0.035 14.7 1.3 0.081 13.6 1.3 1.6 1 0 0 1 1 1 0 Initiation control protein YabA bZIP_1 PF00170.21 CRK42252.1 - 0.066 13.3 0.4 0.13 12.4 0.4 1.5 1 0 0 1 1 1 0 bZIP transcription factor DivIC PF04977.15 CRK42252.1 - 0.091 12.5 3.1 0.19 11.5 3.1 1.5 1 0 0 1 1 1 0 Septum formation initiator SlyX PF04102.12 CRK42252.1 - 1.2 9.9 7.3 7 7.4 7.3 2.4 1 1 0 1 1 1 0 SlyX W2 PF02020.18 CRK42253.1 - 2.3e-22 78.9 2.9 4.9e-22 77.9 2.9 1.6 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon NTP_transferase PF00483.23 CRK42253.1 - 0.00017 21.3 0.0 0.00032 20.4 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 CRK42253.1 - 0.00027 20.6 12.9 0.068 12.9 4.6 3.3 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 CRK42253.1 - 0.0037 16.3 0.3 0.0079 15.2 0.3 1.5 1 0 0 1 1 1 1 L-fucokinase DUF4954 PF16314.5 CRK42253.1 - 0.0039 15.4 2.6 0.0061 14.8 2.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 CRK42253.1 - 0.007 16.1 9.1 0.0089 15.8 3.9 2.7 2 1 1 3 3 3 1 Hexapeptide repeat of succinyl-transferase NTP_transf_3 PF12804.7 CRK42253.1 - 0.0084 16.5 0.2 0.055 13.8 0.0 2.4 3 1 0 3 3 3 1 MobA-like NTP transferase domain HAD_SAK_1 PF10307.9 CRK42255.1 - 4.4e-78 261.7 0.0 5.9e-78 261.3 0.0 1.2 1 0 0 1 1 1 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins MFS_1 PF07690.16 CRK42256.1 - 3.9e-40 137.9 35.7 1.5e-39 136.0 31.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK42256.1 - 1.6e-14 53.7 11.0 1.6e-14 53.7 11.0 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 CRK42256.1 - 5.4e-05 21.8 2.4 7.8e-05 21.3 2.4 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) HAD_SAK_1 PF10307.9 CRK42257.1 - 2e-78 262.9 0.0 2.8e-78 262.4 0.0 1.2 1 0 0 1 1 1 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins Glyco_hydro_72 PF03198.14 CRK42257.1 - 3.9e-12 46.0 0.0 5.8e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 Glucanosyltransferase MFS_1 PF07690.16 CRK42259.1 - 7.1e-40 137.0 37.0 7e-39 133.7 32.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK42259.1 - 1e-14 54.3 9.3 1e-14 54.3 9.3 2.0 2 1 0 2 2 2 1 Sugar (and other) transporter DUF167 PF02594.16 CRK42260.1 - 2.4e-11 43.6 0.1 4.1e-11 42.9 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 Glyco_hydro_72 PF03198.14 CRK42261.1 - 2.6e-115 385.0 2.0 3e-115 384.8 2.0 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 CRK42261.1 - 6e-07 29.2 0.3 2.2e-05 24.1 0.3 2.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 CRK42261.1 - 0.00023 20.4 0.1 0.00059 19.0 0.1 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Guanylate_kin PF00625.21 CRK42262.1 - 8.8e-60 201.5 0.0 1e-59 201.3 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.6 CRK42262.1 - 9.7e-05 22.6 0.1 0.00057 20.1 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CRK42262.1 - 0.00056 20.5 0.0 0.0011 19.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CRK42262.1 - 0.0012 19.2 0.0 0.0018 18.7 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 CRK42262.1 - 0.0076 16.3 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CRK42262.1 - 0.0084 16.0 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 CRK42262.1 - 0.013 15.7 0.0 0.032 14.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 CRK42262.1 - 0.026 14.5 0.0 0.034 14.1 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain ABC_tran PF00005.27 CRK42262.1 - 0.033 14.7 0.1 0.059 13.9 0.1 1.7 1 1 0 1 1 1 0 ABC transporter AAA_28 PF13521.6 CRK42262.1 - 0.099 12.9 0.1 0.18 12.0 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CRK42262.1 - 0.1 12.3 0.1 0.51 10.0 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 CRK42262.1 - 0.12 12.5 0.0 0.22 11.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain An_peroxidase PF03098.15 CRK42263.1 - 3.2e-39 134.9 0.0 1.5e-26 93.1 0.0 3.4 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 CRK42263.1 - 2.7e-06 26.4 0.0 5.9e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 Cytochrome P450 PI_PP_C PF18365.1 CRK42263.1 - 0.024 14.6 0.1 0.06 13.3 0.1 1.6 1 0 0 1 1 1 0 Phosphoinositide phosphatase C-terminal domain Guanylate_kin PF00625.21 CRK42264.1 - 5.8e-59 198.8 0.0 6.8e-59 198.6 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.6 CRK42264.1 - 0.00014 22.1 0.1 0.00079 19.6 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CRK42264.1 - 0.00096 19.7 0.0 0.0019 18.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CRK42264.1 - 0.0045 17.4 0.1 0.0073 16.7 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 CRK42264.1 - 0.0047 17.0 0.0 0.0089 16.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CRK42264.1 - 0.011 15.6 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 CRK42264.1 - 0.018 15.3 0.0 0.042 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 CRK42264.1 - 0.036 14.0 0.0 0.048 13.6 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain ABC_tran PF00005.27 CRK42264.1 - 0.046 14.2 0.1 0.079 13.5 0.1 1.6 1 1 0 1 1 1 0 ABC transporter AAA_14 PF13173.6 CRK42264.1 - 0.14 12.1 0.0 0.3 11.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain An_peroxidase PF03098.15 CRK42265.1 - 1.1e-22 80.3 0.0 3.9e-22 78.5 0.0 1.7 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.22 CRK42265.1 - 8.9e-07 28.0 0.0 4.2e-06 25.8 0.0 1.9 2 0 0 2 2 2 1 Cytochrome P450 Gly-zipper_OmpA PF13436.6 CRK42265.1 - 0.31 10.9 2.5 0.94 9.3 2.5 1.8 1 0 0 1 1 1 0 Glycine-zipper domain DUF2235 PF09994.9 CRK42267.1 - 1.2e-100 336.6 0.1 1.5e-100 336.3 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) AA_permease_2 PF13520.6 CRK42268.1 - 1.9e-68 231.2 18.6 2.5e-68 230.9 18.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CRK42268.1 - 8.8e-21 74.0 16.7 1.2e-20 73.6 16.7 1.1 1 0 0 1 1 1 1 Amino acid permease Aa_trans PF01490.18 CRK42268.1 - 0.082 11.6 10.3 0.34 9.6 10.3 2.1 1 1 0 1 1 1 0 Transmembrane amino acid transporter protein Zn_clus PF00172.18 CRK42271.1 - 1.2e-08 34.9 11.5 2.1e-08 34.1 11.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DivIC PF04977.15 CRK42271.1 - 0.72 9.7 9.1 0.94 9.3 1.7 2.3 2 0 0 2 2 2 0 Septum formation initiator ZapB PF06005.12 CRK42271.1 - 8.8 6.9 8.5 9.6 6.7 4.1 2.4 2 0 0 2 2 2 0 Cell division protein ZapB COesterase PF00135.28 CRK42273.1 - 8.8e-82 275.6 0.0 1.3e-72 245.3 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 CRK42273.1 - 2e-10 40.9 0.0 3.2e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Tannase PF07519.11 CRK42275.1 - 2.2e-94 317.0 0.0 2.9e-94 316.6 0.0 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Aminotran_1_2 PF00155.21 CRK42278.1 - 1.8e-68 231.3 0.0 2.2e-68 231.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DHDPS PF00701.22 CRK42279.1 - 5.4e-48 163.2 0.0 6.4e-48 162.9 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family SnoaL_2 PF12680.7 CRK42280.1 - 0.00019 22.0 0.0 0.00035 21.2 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 CRK42280.1 - 0.11 12.9 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Glyco_hydro_31 PF01055.26 CRK42282.1 - 7.8e-109 364.8 4.2 1.1e-108 364.3 4.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 CRK42282.1 - 0.00016 21.9 1.3 0.00086 19.6 0.1 2.7 2 1 0 2 2 2 1 Galactose mutarotase-like DUF4968 PF16338.5 CRK42282.1 - 0.002 18.4 0.0 0.0034 17.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4968) PAM2 PF07145.15 CRK42282.1 - 0.044 13.5 0.1 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 Ataxin-2 C-terminal region RGS PF00615.19 CRK42283.1 - 4.5e-09 36.6 0.0 7.4e-07 29.5 0.0 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain PAP2 PF01569.21 CRK42285.1 - 1.8e-20 73.1 6.5 1.8e-20 73.1 6.5 2.1 2 1 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 CRK42285.1 - 0.17 12.4 0.3 0.17 12.4 0.3 2.3 2 1 0 2 2 2 0 PAP2 superfamily C-terminal ERp29 PF07749.12 CRK42302.1 - 1.2e-25 90.2 0.2 1.2e-25 90.2 0.2 1.3 2 0 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain Serglycin PF04360.12 CRK42336.1 - 0.11 12.4 0.9 0.21 11.5 0.9 1.4 1 0 0 1 1 1 0 Serglycin Myotub-related PF06602.14 CRK42354.1 - 2.1e-24 86.1 0.2 2.9e-24 85.7 0.2 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Crystall_3 PF08964.10 CRK42354.1 - 0.037 14.2 0.0 0.056 13.6 0.0 1.3 1 0 0 1 1 1 0 Beta/Gamma crystallin PhetRS_B1 PF18262.1 CRK42355.1 - 3.4e-31 107.3 0.2 4e-31 107.1 0.2 1.0 1 0 0 1 1 1 1 Phe-tRNA synthetase beta subunit B1 domain B5 PF03484.15 CRK42355.1 - 0.12 12.7 0.0 0.16 12.3 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetase B5 domain Glyco_hydro_47 PF01532.20 CRK42370.1 - 8.4e-39 133.7 0.1 8.9e-39 133.6 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF4038 PF13204.6 CRK42370.1 - 0.0057 16.3 0.1 0.0064 16.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) MMR_HSR1_Xtn PF16897.5 CRK42387.1 - 3.6e-34 117.0 3.5 1.4e-33 115.1 1.8 1.9 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 CRK42387.1 - 4.9e-14 52.1 0.1 1e-13 51.1 0.0 1.6 2 0 0 2 2 2 1 TGS domain Baculo_ME53 PF06061.11 CRK42387.1 - 0.067 12.4 2.4 0.21 10.8 2.4 1.7 1 1 0 1 1 1 0 Baculoviridae ME53 Pkinase_Tyr PF07714.17 CRK42436.1 - 2.5e-05 23.7 0.1 0.077 12.3 0.0 3.4 3 1 1 4 4 4 2 Protein tyrosine kinase Pkinase PF00069.25 CRK42436.1 - 0.00016 21.1 0.0 0.0011 18.4 0.0 2.3 3 0 0 3 3 3 1 Protein kinase domain SWIM PF04434.17 CRK42438.1 - 0.0005 19.7 0.1 0.0011 18.6 0.1 1.5 1 0 0 1 1 1 1 SWIM zinc finger Dermcidin PF15291.6 CRK42440.1 - 0.056 14.0 0.0 0.12 12.9 0.0 1.6 1 1 0 1 1 1 0 Dermcidin, antibiotic peptide Sulfate_transp PF00916.20 CRK42442.1 - 9.7e-144 478.8 26.9 3.5e-105 351.9 20.2 2.1 2 0 0 2 2 2 2 Sulfate permease family STAS PF01740.21 CRK42442.1 - 4.5e-08 32.7 0.0 1e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 CRK42442.1 - 1.1e-07 32.2 28.0 0.0002 21.7 3.0 5.1 3 3 2 5 5 5 3 Molybdate transporter of MFS superfamily Aft1_HRR PF11787.8 CRK42442.1 - 0.093 13.9 4.6 27 6.0 0.0 4.2 5 0 0 5 5 5 0 Aft1 HRR domain SNN_transmemb PF09049.10 CRK42442.1 - 2.9 7.9 18.6 0.76 9.8 1.4 3.4 3 0 0 3 3 3 0 Stannin transmembrane RabGAP-TBC PF00566.18 CRK42446.1 - 2.4e-37 128.7 0.0 6.7e-25 88.0 0.0 3.4 3 0 0 3 3 3 3 Rab-GTPase-TBC domain RPOL_N PF14700.6 CRK42446.1 - 0.025 14.0 1.6 0.57 9.5 0.0 2.2 1 1 1 2 2 2 0 DNA-directed RNA polymerase N-terminal Bul1_N PF04425.12 CRK42446.1 - 0.063 12.0 12.0 0.64 8.7 2.6 2.1 2 0 0 2 2 2 0 Bul1 N terminus Band_3_cyto PF07565.13 CRK42446.1 - 0.11 12.3 0.2 18 5.0 0.0 2.4 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Podoplanin PF05808.11 CRK42446.1 - 7.2 6.7 5.8 8 6.5 0.3 2.3 2 0 0 2 2 2 0 Podoplanin HlyIII PF03006.20 CRK42448.1 - 1.1e-60 205.1 19.2 1.4e-60 204.9 19.2 1.1 1 0 0 1 1 1 1 Haemolysin-III related Ycf66_N PF07444.11 CRK42448.1 - 0.31 11.2 4.4 0.3 11.2 1.6 2.5 3 1 0 3 3 3 0 Ycf66 protein N-terminus Planc_extracel PF07595.12 CRK42448.1 - 3.5 7.6 6.1 0.23 11.3 0.3 2.1 2 0 0 2 2 2 0 Planctomycete extracellular DUF4131 PF13567.6 CRK42448.1 - 9.9 5.8 8.8 1.6 8.3 2.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) FmiP_Thoc5 PF09766.9 CRK42450.1 - 2.4e-31 109.4 12.3 3.8e-31 108.7 12.3 1.3 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 SPATA1_C PF15743.5 CRK42450.1 - 0.0065 16.5 4.1 0.0065 16.5 4.1 1.9 2 1 0 2 2 2 1 Spermatogenesis-associated C-terminus NEXCaM_BD PF16644.5 CRK42450.1 - 0.046 14.0 2.4 2.4 8.4 1.2 2.1 2 0 0 2 2 2 0 Regulatory region of Na+/H+ exchanger NHE binds to calmodulin Glyco_hydro_3_C PF01915.22 CRK42450.1 - 0.12 12.3 0.9 2 8.3 0.0 2.1 1 1 1 2 2 2 0 Glycosyl hydrolase family 3 C-terminal domain YabA PF06156.13 CRK42450.1 - 0.43 11.2 7.1 4.2 8.1 2.3 2.3 2 0 0 2 2 2 0 Initiation control protein YabA Pinin_SDK_memA PF04696.13 CRK42450.1 - 2.2 8.3 13.1 0.68 10.0 8.4 2.1 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region Glyco_trans_2_3 PF13632.6 CRK42452.1 - 1.2e-16 61.2 0.3 1.2e-16 61.2 0.3 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 FKBP_C PF00254.28 CRK42456.1 - 1.2e-31 108.8 0.0 2.3e-31 108.0 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 CRK42456.1 - 7.1e-25 87.6 0.2 2.1e-24 86.1 0.2 1.8 1 1 0 1 1 1 1 Nucleoplasmin-like domain Nop14 PF04147.12 CRK42456.1 - 0.47 8.6 20.8 0.6 8.3 20.8 1.0 1 0 0 1 1 1 0 Nop14-like family NARP1 PF12569.8 CRK42456.1 - 3.4 6.5 5.6 4.3 6.1 5.6 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Pkinase PF00069.25 CRK42458.1 - 1.8e-64 217.7 0.2 9.9e-32 110.3 0.0 3.4 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CRK42458.1 - 3e-33 115.2 0.0 1.7e-17 63.6 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CRK42458.1 - 2.5e-10 40.7 9.8 0.00013 21.9 1.5 3.0 2 2 0 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 CRK42458.1 - 1.9e-08 34.0 0.1 0.0063 15.9 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 CRK42458.1 - 1.3e-07 30.9 1.3 0.008 15.2 0.1 2.2 2 0 0 2 2 2 2 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 CRK42458.1 - 4.9e-05 22.5 0.1 0.28 10.1 0.0 2.1 2 0 0 2 2 2 2 Poxvirus serine/threonine protein kinase Kdo PF06293.14 CRK42458.1 - 0.00014 21.3 1.0 0.49 9.7 0.1 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 CRK42458.1 - 0.00072 18.7 0.2 1.2 8.1 0.0 2.3 2 0 0 2 2 2 2 Seadornavirus VP7 FTA2 PF13095.6 CRK42458.1 - 0.016 14.8 0.0 8 6.0 0.0 2.6 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 DUF1668 PF07893.13 CRK42458.1 - 0.034 13.5 0.2 0.57 9.5 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1668) DUF4760 PF15956.5 CRK42458.1 - 0.055 13.6 0.1 16 5.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4760) PIP49_C PF12260.8 CRK42458.1 - 0.12 12.0 0.2 21 4.7 0.0 2.4 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 Exo_endo_phos PF03372.23 CRK42460.1 - 3.2e-09 36.6 4.5 5.7e-09 35.8 4.5 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.32 CRK42462.1 - 5.4e-24 84.0 0.7 3.2e-11 43.6 0.2 2.6 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK42462.1 - 1.4e-08 34.9 0.0 9.9e-05 22.6 0.0 2.2 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CRK42462.1 - 0.00035 19.6 0.0 0.62 9.0 0.0 2.1 1 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 CRK42462.1 - 0.15 12.1 0.3 1.6 8.8 0.0 3.6 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat ChiW_Ig_like PF18683.1 CRK42463.1 - 0.013 15.7 0.0 0.021 15.1 0.0 1.2 1 0 0 1 1 1 0 Chitinase W immunoglobulin-like domain WD40 PF00400.32 CRK42465.1 - 5e-15 55.6 11.0 0.0017 19.1 0.2 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK42465.1 - 7.4e-08 32.6 0.0 0.023 15.0 0.0 4.4 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 CRK42465.1 - 0.0011 18.8 0.2 6.5 6.8 0.0 3.6 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat RRM_1 PF00076.22 CRK42468.1 - 9.6e-09 34.9 0.0 2.6e-08 33.6 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CRK42468.1 - 7.2e-06 25.6 0.0 1e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_47 PF01532.20 CRK42470.1 - 2e-138 462.1 0.2 7.8e-116 387.7 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 47 SnoaL_2 PF12680.7 CRK42472.1 - 0.0099 16.5 0.4 0.069 13.8 0.0 2.3 2 1 0 2 2 2 1 SnoaL-like domain SnoaL PF07366.12 CRK42472.1 - 0.11 12.2 0.0 0.31 10.8 0.0 1.8 1 1 0 1 1 1 0 SnoaL-like polyketide cyclase adh_short_C2 PF13561.6 CRK42474.1 - 9.8e-14 51.5 0.0 4e-08 33.1 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRK42474.1 - 1.5e-06 27.8 0.0 1.8e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CRK42474.1 - 0.0099 15.8 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 CRK42474.1 - 0.037 13.8 0.0 0.06 13.1 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Per1 PF04080.13 CRK42476.1 - 5.1e-100 334.5 10.4 9.1e-100 333.6 10.4 1.4 1 0 0 1 1 1 1 Per1-like family adh_short_C2 PF13561.6 CRK42476.1 - 2.1e-39 135.5 2.4 3.4e-39 134.8 2.4 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CRK42476.1 - 6.5e-31 107.3 1.4 1.3e-30 106.4 1.4 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CRK42476.1 - 7.9e-08 32.4 2.8 5.4e-07 29.7 2.8 2.1 1 1 0 1 1 1 1 KR domain NUC173 PF08161.12 CRK42476.1 - 0.088 12.5 0.1 0.37 10.4 0.0 1.9 2 0 0 2 2 2 0 NUC173 domain DUF3522 PF12036.8 CRK42476.1 - 0.23 11.7 8.7 0.69 10.2 8.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3522) DUF1772 PF08592.11 CRK42477.1 - 5.1e-05 23.6 9.2 0.00033 21.0 9.2 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) DUF5549 PF17703.1 CRK42477.1 - 9 5.9 9.3 1.4 8.6 3.8 2.3 2 1 0 3 3 3 0 Family of unknown function (DUF5549) DUF1772 PF08592.11 CRK42478.1 - 1.3e-05 25.5 8.3 6.7e-05 23.2 8.3 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) Per1 PF04080.13 CRK42479.1 - 2.1e-104 348.8 10.6 2.6e-104 348.5 10.6 1.1 1 0 0 1 1 1 1 Per1-like family DUF3522 PF12036.8 CRK42479.1 - 0.035 14.4 8.8 0.064 13.5 8.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3522) CCD PF07860.11 CRK42479.1 - 0.17 11.9 0.0 0.36 10.9 0.0 1.5 1 0 0 1 1 1 0 WisP family C-Terminal Region Lum_binding PF00677.17 CRK42480.1 - 1.3e-46 156.5 1.1 3.1e-23 81.5 0.5 2.1 2 0 0 2 2 2 2 Lumazine binding domain ERCC4 PF02732.15 CRK42481.1 - 1e-22 81.0 0.1 1.5e-22 80.4 0.1 1.3 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.6 CRK42481.1 - 0.0068 16.7 0.0 0.025 14.9 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain DUF4373 PF14297.6 CRK42481.1 - 0.13 13.1 0.2 0.37 11.6 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4373) PGM_PMM_I PF02878.16 CRK42482.1 - 2e-21 76.2 0.2 2.8e-10 40.0 0.0 3.3 2 1 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 CRK42482.1 - 8.5e-12 45.1 0.8 2.7e-11 43.5 0.5 2.1 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 CRK42482.1 - 0.00038 20.6 0.1 0.0011 19.1 0.1 1.9 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 CRK42482.1 - 0.018 15.7 0.2 0.2 12.3 0.2 2.8 1 1 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Zn_clus PF00172.18 CRK42484.1 - 7.6e-06 26.0 8.5 1.3e-05 25.2 8.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 CRK42485.1 - 5.4e-08 32.8 14.4 5.4e-08 32.8 14.4 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 CRK42485.1 - 2.3e-07 30.1 0.0 4.4e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DinB_2 PF12867.7 CRK42485.1 - 0.12 12.9 0.0 0.89 10.1 0.0 2.4 2 0 0 2 2 2 0 DinB superfamily MFS_1 PF07690.16 CRK42486.1 - 9.7e-33 113.5 28.4 9.7e-33 113.5 28.4 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK42486.1 - 3.4e-09 36.1 12.1 3.4e-09 36.1 12.1 3.1 3 1 1 4 4 4 1 Sugar (and other) transporter CFEM PF05730.11 CRK42489.1 - 6.9e-11 42.1 10.1 6.9e-11 42.1 10.1 2.2 3 0 0 3 3 3 1 CFEM domain Sporozoite_P67 PF05642.11 CRK42489.1 - 0.055 11.6 7.1 0.059 11.4 7.1 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FAM199X PF15814.5 CRK42489.1 - 1.5 7.8 5.7 2.2 7.3 5.7 1.2 1 0 0 1 1 1 0 Protein family FAM199X AvrM_N PF18247.1 CRK42490.1 - 0.12 12.4 0.0 0.36 10.8 0.0 1.7 2 0 0 2 2 2 0 Flax-rust effector AvrM N-terminal domain CTC1 PF15489.6 CRK42491.1 - 0.061 10.8 0.0 0.07 10.6 0.0 1.0 1 0 0 1 1 1 0 CST, telomere maintenance, complex subunit CTC1 TetR_C_28 PF17937.1 CRK42492.1 - 0.00037 20.9 2.7 0.92 10.0 0.2 3.0 2 0 0 2 2 2 2 Tetracyclin repressor-like, C-terminal domain SM-ATX PF14438.6 CRK42492.1 - 0.0034 17.5 0.0 2.5 8.3 0.0 2.5 2 0 0 2 2 2 1 Ataxin 2 SM domain CorA PF01544.18 CRK42492.1 - 0.0093 15.3 19.1 0.18 11.1 1.1 4.2 4 0 0 4 4 4 2 CorA-like Mg2+ transporter protein Baculo_PEP_C PF04513.12 CRK42492.1 - 0.012 15.7 2.0 5.6 7.0 0.0 2.9 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TcdB_N PF12918.7 CRK42492.1 - 0.018 15.3 0.0 13 6.2 0.0 2.7 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain Sulphotransf PF09037.10 CRK42492.1 - 0.022 14.3 0.7 4.9 6.6 0.1 2.3 2 0 0 2 2 2 0 Stf0 sulphotransferase CCDC85 PF10226.9 CRK42492.1 - 0.038 13.7 4.8 2 8.0 0.5 3.1 2 2 0 2 2 2 0 CCDC85 family YojJ PF10372.9 CRK42492.1 - 0.042 13.9 0.0 14 5.8 0.0 3.0 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus RhoGAP PF00620.27 CRK42492.1 - 0.044 13.6 2.4 10 5.9 0.2 3.3 3 2 0 3 3 3 0 RhoGAP domain ApoLp-III PF07464.11 CRK42492.1 - 0.047 13.8 8.8 4.1 7.5 0.0 4.1 3 2 0 4 4 4 0 Apolipophorin-III precursor (apoLp-III) DUF5316 PF17247.2 CRK42492.1 - 0.059 13.4 0.1 15 5.7 0.0 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5316) DUF5490 PF17593.2 CRK42492.1 - 0.086 12.9 1.3 6.3 6.9 0.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5490) Peptidase_S78_2 PF14550.6 CRK42492.1 - 0.1 12.7 0.4 12 6.0 0.1 2.4 2 0 0 2 2 2 0 Putative phage serine protease XkdF DUF1098 PF06497.11 CRK42492.1 - 0.12 12.8 2.1 1.4 9.4 0.1 3.3 2 2 2 4 4 4 0 Protein of unknown function (DUF1098) Polysacc_synt PF01943.17 CRK42492.1 - 0.2 11.0 1.6 5.9 6.2 0.1 2.2 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein RSN1_TM PF13967.6 CRK42492.1 - 0.28 10.9 5.2 1.5 8.6 0.5 3.1 3 0 0 3 3 3 0 Late exocytosis, associated with Golgi transport Ferredoxin_N PF16947.5 CRK42492.1 - 1 9.5 3.0 18 5.5 0.2 2.5 2 0 0 2 2 2 0 N-terminal region of 4Fe-4S ferredoxin iron-sulfur binding Mis14 PF08641.12 CRK42492.1 - 2.3 8.5 5.0 10 6.4 0.1 3.4 2 2 2 4 4 4 0 Kinetochore protein Mis14 like IF2_N PF04760.15 CRK42492.1 - 3.7 7.4 8.2 56 3.7 0.2 4.3 4 0 0 4 4 4 0 Translation initiation factor IF-2, N-terminal region CK2S PF15011.6 CRK42492.1 - 8.7 6.2 13.5 1.7 8.5 0.4 3.6 2 2 1 4 4 4 0 Casein Kinase 2 substrate Trypan_PARP PF05887.11 CRK42493.1 - 0.00034 20.6 22.3 0.00034 20.6 22.3 16.5 6 3 8 16 16 16 2 Procyclic acidic repetitive protein (PARP) zf-C2H2 PF00096.26 CRK42495.1 - 9.7e-13 47.8 11.2 3.6e-06 27.1 2.3 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CRK42495.1 - 1.6e-12 47.2 6.9 2.9e-07 30.6 0.2 4.0 3 0 0 3 3 3 3 Zinc-finger double domain ADH_zinc_N PF00107.26 CRK42495.1 - 7.7e-12 45.3 0.0 1.4e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase zf-C2H2_4 PF13894.6 CRK42495.1 - 4.3e-08 33.3 10.2 0.0012 19.5 1.4 4.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CRK42495.1 - 1.2e-07 31.5 5.2 0.00073 19.5 0.3 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger ADH_N PF08240.12 CRK42495.1 - 3.8e-05 23.5 0.1 0.00012 21.9 0.1 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain zf-C2H2_jaz PF12171.8 CRK42495.1 - 0.00011 22.4 2.5 0.52 10.7 0.2 3.8 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CRK42495.1 - 0.00015 22.0 1.8 0.019 15.3 0.3 3.2 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 CRK42495.1 - 0.031 14.0 4.2 1.7 8.5 0.5 3.5 3 0 0 3 3 3 0 zinc-finger C2H2-type ADH_zinc_N_2 PF13602.6 CRK42495.1 - 0.047 14.7 0.0 0.095 13.8 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase zf-Di19 PF05605.12 CRK42495.1 - 0.12 12.7 1.4 0.3 11.4 1.4 1.7 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Zn_ribbon_recom PF13408.6 CRK42495.1 - 0.33 11.5 2.8 0.38 11.3 0.8 2.0 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-C2HE PF16278.5 CRK42495.1 - 0.71 10.4 2.7 12 6.4 0.5 2.6 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger LIM PF00412.22 CRK42495.1 - 0.75 10.1 3.4 23 5.3 0.2 2.4 1 1 1 2 2 2 0 LIM domain zf-BED PF02892.15 CRK42495.1 - 1.2 9.3 2.9 34 4.6 2.9 2.7 1 1 0 1 1 1 0 BED zinc finger eIF3_subunit PF08597.10 CRK42496.1 - 1.3e-72 244.6 26.5 1.4e-72 244.5 26.5 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit LMBR1 PF04791.16 CRK42496.1 - 0.23 10.3 2.2 0.33 9.8 2.2 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Rrn6 PF10214.9 CRK42496.1 - 0.98 7.8 8.9 1.6 7.2 8.9 1.3 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor CDC27 PF09507.10 CRK42496.1 - 1.7 8.0 24.9 0.085 12.2 17.1 2.0 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 MDM31_MDM32 PF08118.11 CRK42497.1 - 1.1e-249 829.5 0.0 1.3e-249 829.3 0.0 1.0 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins KH_8 PF17903.1 CRK42498.1 - 0.00016 21.7 0.0 0.00035 20.6 0.0 1.5 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 CRK42498.1 - 0.072 12.9 0.3 0.16 11.9 0.3 1.6 1 0 0 1 1 1 0 KH domain eIF-3_zeta PF05091.12 CRK42499.1 - 3.1e-190 633.6 0.0 6.5e-190 632.5 0.0 1.4 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) bZIP_1 PF00170.21 CRK42499.1 - 4.3e-05 23.5 8.0 8.5e-05 22.6 8.0 1.4 1 0 0 1 1 1 1 bZIP transcription factor DUF569 PF04601.13 CRK42499.1 - 0.018 14.7 0.1 0.057 13.1 0.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF569) NARG2_C PF10505.9 CRK42499.1 - 0.081 12.4 0.0 10 5.5 0.0 2.2 2 0 0 2 2 2 0 NMDA receptor-regulated gene protein 2 C-terminus bZIP_2 PF07716.15 CRK42499.1 - 0.91 9.7 8.6 0.4 10.8 5.6 2.0 1 1 1 2 2 2 0 Basic region leucine zipper Acyltransferase PF01553.21 CRK42500.1 - 8.3e-14 51.4 0.0 1.1e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 CRK42500.1 - 2.5e-11 43.5 0.4 8.1e-11 41.9 0.4 1.8 1 0 0 1 1 1 1 Acyltransferase C-terminus LAL_C2 PF18603.1 CRK42500.1 - 0.02 15.1 0.0 0.034 14.3 0.0 1.4 1 0 0 1 1 1 0 L-amino acid ligase C-terminal domain 2 Aldedh PF00171.22 CRK42501.1 - 3.1e-104 349.1 0.2 3.1e-104 349.1 0.2 2.1 2 0 0 2 2 2 1 Aldehyde dehydrogenase family HLH PF00010.26 CRK42501.1 - 1.5e-11 44.0 0.2 1.5e-11 44.0 0.2 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Aldedh PF00171.22 CRK42502.1 - 3.3e-69 233.6 0.2 4.4e-69 233.2 0.2 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family FIST_C PF10442.9 CRK42502.1 - 0.063 13.3 0.0 0.19 11.7 0.0 1.8 2 0 0 2 2 2 0 FIST C domain Utp14 PF04615.13 CRK42556.1 - 1.3e-30 106.7 0.4 1.5e-30 106.5 0.4 1.0 1 0 0 1 1 1 1 Utp14 protein tRNA_anti-codon PF01336.25 CRK42556.1 - 0.0052 16.7 0.1 0.0087 16.0 0.1 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DDOST_48kD PF03345.14 CRK42571.1 - 4.5e-39 134.5 0.7 4.9e-39 134.4 0.7 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta HRG PF16954.5 CRK42571.1 - 0.082 13.3 1.1 10 6.6 0.0 2.3 1 1 1 2 2 2 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene Guanylate_cyc PF00211.20 CRK42580.1 - 5.1e-14 52.3 0.0 3.6e-12 46.3 0.0 2.0 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain DNA_pol_B PF00136.21 CRK42582.1 - 1.2e-34 119.9 0.0 1.3e-34 119.7 0.0 1.0 1 0 0 1 1 1 1 DNA polymerase family B Pex26 PF07163.12 CRK42582.1 - 0.092 12.0 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Pex26 protein CPSase_L_D2 PF02786.17 CRK42588.1 - 2e-26 92.8 0.0 2.6e-26 92.4 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain OTCace PF00185.24 CRK42588.1 - 2.1e-17 63.7 0.2 2.3e-17 63.5 0.2 1.1 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Dala_Dala_lig_C PF07478.13 CRK42588.1 - 1.8e-05 24.3 0.0 2e-05 24.2 0.0 1.3 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus Pyrophosphatase PF00719.19 CRK42595.1 - 1e-42 145.7 0.0 1.4e-42 145.3 0.0 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase Peptidase_S10 PF00450.22 CRK42596.1 - 2.2e-87 294.2 0.0 7.1e-87 292.5 0.0 1.9 2 0 0 2 2 2 1 Serine carboxypeptidase RTA1 PF04479.13 CRK42596.1 - 1e-55 188.6 8.2 2e-55 187.6 8.2 1.4 1 0 0 1 1 1 1 RTA1 like protein Abhydrolase_3 PF07859.13 CRK42596.1 - 1.7e-16 60.8 0.3 5.6e-16 59.0 0.7 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 CRK42596.1 - 4e-09 35.8 0.0 8e-09 34.8 0.0 1.4 1 0 0 1 1 1 1 Steryl acetyl hydrolase Glyco_hydro_18 PF00704.28 CRK42597.1 - 2.3e-18 67.0 0.0 3.9e-18 66.2 0.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 F-box PF00646.33 CRK42599.1 - 0.014 15.3 0.9 0.12 12.3 0.0 2.4 2 0 0 2 2 2 0 F-box domain DUF2721 PF11026.8 CRK42599.1 - 0.023 14.6 1.3 3.5 7.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) DUF4448 PF14610.6 CRK42599.1 - 0.082 12.7 4.2 1.9 8.2 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) 7TM_GPCR_Srz PF10325.9 CRK42599.1 - 2 7.7 15.3 4.1 6.7 3.1 2.6 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srz TrkH PF02386.16 CRK42600.1 - 7.1e-119 397.5 5.0 1.4e-117 393.2 5.6 1.9 2 0 0 2 2 2 2 Cation transport protein Na_H_Exchanger PF00999.21 CRK42602.1 - 3e-41 141.5 22.9 3.8e-41 141.2 22.9 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Amidohydro_1 PF01979.20 CRK42603.1 - 1.1e-07 31.5 0.0 1.5e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 CRK42603.1 - 0.0002 21.0 0.2 0.00078 19.0 0.0 1.8 1 1 0 2 2 2 1 Amidohydrolase family Amidohydro_1 PF01979.20 CRK42604.1 - 1.6e-28 100.1 0.7 1.5e-16 60.7 0.0 2.6 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 CRK42604.1 - 5.5e-16 59.1 5.5 1.4e-05 24.8 0.2 3.9 3 1 0 4 4 4 3 Amidohydrolase family DUF1996 PF09362.10 CRK42607.1 - 5.6e-82 275.3 0.6 7.6e-82 274.8 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) DUF1996 PF09362.10 CRK42608.1 - 2.6e-82 276.4 0.9 3.4e-82 276.0 0.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) TPR_2 PF07719.17 CRK42609.1 - 7.2e-05 22.6 0.1 6.4 7.1 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CRK42609.1 - 0.00031 21.0 0.5 0.038 14.3 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 CRK42609.1 - 0.0014 18.3 0.0 0.57 10.1 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat DnaJ PF00226.31 CRK42609.1 - 0.024 14.7 0.0 0.066 13.4 0.0 1.7 1 0 0 1 1 1 0 DnaJ domain UBA PF00627.31 CRK42609.1 - 0.029 14.3 0.1 0.064 13.2 0.1 1.6 1 0 0 1 1 1 0 UBA/TS-N domain DnaJ PF00226.31 CRK42610.1 - 0.0016 18.5 0.1 0.0036 17.4 0.0 1.6 2 0 0 2 2 2 1 DnaJ domain UQ_con PF00179.26 CRK42611.1 - 1.1e-63 213.0 0.1 4.3e-48 162.5 0.0 2.0 1 1 1 2 2 2 2 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CRK42611.1 - 0.039 13.7 0.2 0.19 11.5 0.1 2.1 1 1 1 2 2 2 0 Prokaryotic E2 family B BPS PF08947.10 CRK42611.1 - 0.25 11.2 1.4 20 5.1 0.1 2.3 2 0 0 2 2 2 0 BPS (Between PH and SH2) DUF2805 PF10985.8 CRK42611.1 - 1.2 9.6 4.3 2.3 8.6 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2805) LSM PF01423.22 CRK42613.1 - 4.7e-16 58.2 0.2 6.3e-16 57.8 0.2 1.2 1 0 0 1 1 1 1 LSM domain TerB_C PF15615.6 CRK42614.1 - 0.14 12.4 1.0 30 4.9 0.1 3.0 2 0 0 2 2 2 0 TerB-C domain Phage_holin_2_4 PF16082.5 CRK42614.1 - 0.15 11.8 0.4 0.39 10.5 0.4 1.7 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like Voldacs PF03517.13 CRK42616.1 - 1.3e-22 80.4 0.2 1.3e-21 77.2 0.2 2.2 1 1 0 1 1 1 1 Regulator of volume decrease after cellular swelling Selenoprotein_S PF06936.11 CRK42617.1 - 0.032 14.0 0.2 0.051 13.4 0.2 1.2 1 0 0 1 1 1 0 Selenoprotein S (SelS) zf-C2H2_2 PF12756.7 CRK42618.1 - 2.8e-22 78.9 3.1 1.2e-20 73.7 0.4 2.2 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) SUZ-C PF12901.7 CRK42618.1 - 0.056 13.5 0.5 4.3 7.4 0.1 2.7 2 0 0 2 2 2 0 SUZ-C motif zf-C2H2_4 PF13894.6 CRK42618.1 - 0.27 12.2 9.2 4.4 8.4 0.2 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger Pkinase PF00069.25 CRK42620.1 - 6.4e-14 52.0 0.0 9.2e-11 41.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CRK42620.1 - 1.9e-08 33.9 0.0 0.0017 17.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CRK42620.1 - 0.0014 18.6 0.2 0.0041 17.1 0.2 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CRK42620.1 - 0.0023 17.5 0.0 0.0058 16.2 0.0 1.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase DPPIV_N PF00930.21 CRK42622.1 - 9.3e-135 448.9 0.0 2.3e-70 237.1 0.0 3.3 3 0 0 3 3 3 3 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 CRK42622.1 - 1e-68 231.0 8.6 4.8e-34 117.7 1.3 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Helicase_C PF00271.31 CRK42622.1 - 1.6e-18 67.1 0.0 3e-17 63.0 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CRK42622.1 - 8.9e-12 45.1 0.8 8.3e-11 42.0 0.0 2.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase Abhydrolase_6 PF12697.7 CRK42622.1 - 9.5e-09 36.2 4.1 0.0032 18.1 0.0 3.2 3 0 0 3 3 3 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CRK42622.1 - 3.1e-08 33.2 0.0 0.025 13.8 0.0 3.8 4 0 0 4 4 4 2 Serine aminopeptidase, S33 ESX-1_EspG PF14011.6 CRK42622.1 - 0.0015 18.2 0.3 0.003 17.2 0.3 1.4 1 0 0 1 1 1 1 EspG family Abhydrolase_3 PF07859.13 CRK42622.1 - 0.0017 18.2 0.0 2.5 7.9 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold RecQ_Zn_bind PF16124.5 CRK42622.1 - 0.0024 18.6 0.4 0.0061 17.3 0.4 1.7 1 0 0 1 1 1 1 RecQ zinc-binding DUF2920 PF11144.8 CRK42622.1 - 0.0047 16.1 0.0 3.3 6.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF2920) AXE1 PF05448.12 CRK42622.1 - 0.0081 14.9 0.0 3.9 6.1 0.0 2.4 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Thioesterase PF00975.20 CRK42622.1 - 0.013 15.6 0.0 7.6 6.6 0.0 2.4 2 0 0 2 2 2 0 Thioesterase domain Abhydrolase_8 PF06259.12 CRK42622.1 - 0.05 13.2 0.0 15 5.1 0.0 2.6 2 0 0 2 2 2 0 Alpha/beta hydrolase HEM4 PF02602.15 CRK42622.1 - 0.18 11.1 0.2 0.49 9.7 0.3 1.6 2 0 0 2 2 2 0 Uroporphyrinogen-III synthase HemD DEAD PF00270.29 CRK42625.1 - 9.4e-25 87.4 0.1 4.5e-23 81.9 0.0 2.7 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CRK42625.1 - 2.3e-19 69.8 0.0 1e-17 64.5 0.1 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CRK42625.1 - 1.1e-05 25.5 0.0 2.8e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RecQ_Zn_bind PF16124.5 CRK42625.1 - 0.00077 20.1 0.4 0.0022 18.7 0.4 1.8 1 0 0 1 1 1 1 RecQ zinc-binding AAA_30 PF13604.6 CRK42625.1 - 0.0057 16.4 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain HEM4 PF02602.15 CRK42625.1 - 0.0076 15.6 0.2 0.05 13.0 0.2 2.1 2 0 0 2 2 2 1 Uroporphyrinogen-III synthase HemD Glyco_tran_WecB PF03808.13 CRK42625.1 - 0.11 12.4 0.1 0.3 11.0 0.1 1.7 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family Glyco_hydro_3_C PF01915.22 CRK42628.1 - 1.1e-08 35.3 0.1 1.9e-07 31.2 0.0 2.5 2 1 1 3 3 3 1 Glycosyl hydrolase family 3 C-terminal domain Abhydrolase_6 PF12697.7 CRK42628.1 - 3.2e-06 27.9 5.9 3.2e-06 27.9 5.9 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CRK42628.1 - 4.7e-06 26.4 0.3 9.4e-06 25.5 0.3 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Glyco_hydro_3 PF00933.21 CRK42628.1 - 0.031 13.6 0.0 0.055 12.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3 PF00933.21 CRK42629.1 - 6.2e-50 170.4 0.0 8.4e-50 169.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Abhydrolase_1 PF00561.20 CRK42629.1 - 3.4e-10 40.0 0.6 6e-10 39.2 0.6 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Glyco_hydro_3_C PF01915.22 CRK42629.1 - 1.5e-08 34.9 0.0 2.1e-07 31.1 0.0 2.2 1 1 1 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Abhydrolase_6 PF12697.7 CRK42629.1 - 2.6e-08 34.8 7.1 1e-07 32.8 7.1 2.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CRK42629.1 - 0.085 12.1 0.1 0.19 11.0 0.1 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Esterase PF00756.20 CRK42629.1 - 0.16 11.5 0.1 0.39 10.3 0.1 1.5 1 0 0 1 1 1 0 Putative esterase Na_Ca_ex PF01699.24 CRK42630.1 - 1.6e-32 112.6 36.5 2.4e-18 66.6 16.4 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF2569 PF10754.9 CRK42630.1 - 0.77 10.2 19.8 0.04 14.4 4.5 2.8 2 2 0 2 2 2 0 Protein of unknown function (DUF2569) FLILHELTA PF10306.9 CRK42631.1 - 1.2e-27 96.1 0.2 2e-27 95.4 0.2 1.3 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.13 CRK42631.1 - 0.017 15.7 0.1 0.025 15.1 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1279) NDK PF00334.19 CRK42632.1 - 2e-13 50.5 0.0 2.8e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Lectin_N PF03954.14 CRK42632.1 - 0.11 12.3 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain Glyco_hydro_31 PF01055.26 CRK42633.1 - 1.4e-138 462.8 3.9 2e-138 462.3 3.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 CRK42633.1 - 3.8e-24 84.8 0.2 1.2e-23 83.2 0.2 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like DUF5110 PF17137.4 CRK42633.1 - 3.6e-07 30.3 0.3 1.1e-06 28.8 0.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) MS_channel PF00924.18 CRK42634.1 - 2.6e-20 72.9 0.5 4.2e-20 72.2 0.5 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_7 PF13499.6 CRK42634.1 - 0.0048 17.3 0.1 0.014 15.8 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 CRK42634.1 - 0.04 13.8 0.1 0.13 12.3 0.1 1.9 1 0 0 1 1 1 0 EF-hand domain EF-hand_5 PF13202.6 CRK42634.1 - 0.058 12.9 0.8 0.17 11.4 0.8 1.7 1 0 0 1 1 1 0 EF hand DUF3671 PF12420.8 CRK42634.1 - 0.13 12.3 1.9 0.3 11.2 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function GST_N_3 PF13417.6 CRK42635.1 - 8.6e-16 58.1 0.0 1.6e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CRK42635.1 - 3.7e-15 56.0 0.0 6.3e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 CRK42635.1 - 5.1e-14 52.4 0.0 9.5e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CRK42635.1 - 0.00035 20.5 0.5 0.00066 19.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 CRK42635.1 - 0.0005 20.2 0.0 0.0009 19.4 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin GST_C_3 PF14497.6 CRK42635.1 - 0.018 15.2 0.0 0.033 14.4 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CRK42635.1 - 0.056 13.7 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF3759 PF12585.8 CRK42637.1 - 5.6e-41 138.5 4.3 1.1e-40 137.5 4.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) GRP PF07172.11 CRK42637.1 - 0.66 10.7 10.4 0.77 10.5 9.4 1.6 2 0 0 2 2 2 0 Glycine rich protein family DUF4834 PF16118.5 CRK42637.1 - 2.9 8.9 0.0 2.9 8.9 0.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) Cyt-b5 PF00173.28 CRK42638.1 - 1e-14 54.4 0.1 2.8e-06 27.4 0.0 4.8 5 0 0 5 5 5 3 Cytochrome b5-like Heme/Steroid binding domain RecQ5 PF06959.11 CRK42638.1 - 0.44 10.5 4.3 0.92 9.4 4.3 1.4 1 0 0 1 1 1 0 RecQ helicase protein-like 5 (RecQ5) CHRD PF07452.12 CRK42639.1 - 1.1e-12 48.9 0.0 2.4e-12 47.8 0.0 1.5 2 0 0 2 2 2 1 CHRD domain GMC_oxred_N PF00732.19 CRK42641.1 - 3e-55 187.7 0.0 3.9e-55 187.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 CRK42641.1 - 2.8e-37 128.4 0.0 5.5e-37 127.5 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 CRK42641.1 - 0.0025 17.0 1.2 0.0026 16.9 0.2 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 CRK42641.1 - 0.0043 16.7 0.9 0.025 14.2 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CRK42641.1 - 0.009 15.3 0.9 0.065 12.5 0.1 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CRK42641.1 - 0.054 13.7 0.5 0.17 12.1 0.4 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Peptidase_M43 PF05572.13 CRK42643.1 - 8.6e-10 38.7 0.0 2e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 CRK42643.1 - 0.00041 20.9 0.0 0.0015 19.0 0.0 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 CRK42643.1 - 0.0092 16.2 0.1 0.019 15.2 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 CRK42643.1 - 0.01 15.5 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 CRK42643.1 - 0.025 14.4 0.0 0.049 13.5 0.0 1.4 1 0 0 1 1 1 0 Matrixin DUF4953 PF16313.5 CRK42643.1 - 0.089 12.0 0.2 0.16 11.1 0.2 1.3 1 0 0 1 1 1 0 Met-zincin Peptidase_M66 PF10462.9 CRK42643.1 - 0.11 11.4 0.1 0.18 10.7 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 NMT1 PF09084.11 CRK42646.1 - 0.021 14.8 0.0 0.42 10.5 0.0 2.0 1 1 1 2 2 2 0 NMT1/THI5 like NMT1_2 PF13379.6 CRK42646.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 NMT1-like family F-box-like PF12937.7 CRK42648.1 - 0.002 18.0 0.4 0.0055 16.6 0.4 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CRK42648.1 - 0.031 14.2 1.4 0.26 11.2 0.3 2.7 2 1 0 2 2 2 0 F-box domain MFS_1 PF07690.16 CRK42651.1 - 2.7e-22 79.2 29.0 4e-18 65.5 13.0 2.3 3 0 0 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK42651.1 - 0.019 13.9 9.3 0.0078 15.1 5.8 1.8 2 1 0 2 2 2 0 Sugar (and other) transporter MFS_1 PF07690.16 CRK42653.1 - 3.9e-31 108.3 31.8 3.5e-27 95.3 11.6 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily MWFE PF15879.5 CRK42653.1 - 0.65 10.2 0.1 0.65 10.2 0.1 3.2 4 0 0 4 4 4 0 NADH-ubiquinone oxidoreductase MWFE subunit Melibiase_2 PF16499.5 CRK42655.1 - 3.4e-57 193.8 3.8 5.2e-56 189.9 3.8 2.1 1 1 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 CRK42655.1 - 2.3e-09 37.2 0.3 1.5e-08 34.5 0.0 2.5 3 0 0 3 3 3 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 CRK42655.1 - 2e-06 27.0 0.0 3.4e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Melibiase MFS_1 PF07690.16 CRK42657.1 - 1.3e-15 57.2 3.5 1.7e-15 56.8 3.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Rep_4 PF05797.11 CRK42657.1 - 0.23 10.6 0.0 0.31 10.1 0.0 1.1 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) Fungal_trans PF04082.18 CRK42658.1 - 1.6e-12 47.1 0.1 2.3e-12 46.5 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK42658.1 - 0.00042 20.4 11.5 0.00077 19.5 11.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF5605 PF18310.1 CRK42658.1 - 0.12 12.3 0.5 0.25 11.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5605) Sugar_tr PF00083.24 CRK42659.1 - 2e-83 280.7 33.4 2.4e-83 280.5 33.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CRK42659.1 - 8.7e-20 70.9 43.4 4.8e-18 65.2 32.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_12 PF13424.6 CRK42660.1 - 4.4e-06 26.9 5.4 0.0048 17.2 0.7 4.0 2 1 3 5 5 5 4 Tetratricopeptide repeat NACHT PF05729.12 CRK42660.1 - 0.00043 20.2 0.0 0.0017 18.3 0.0 2.0 1 1 0 1 1 1 1 NACHT domain TPR_19 PF14559.6 CRK42660.1 - 0.0036 17.8 0.1 0.0036 17.8 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat AAA_22 PF13401.6 CRK42660.1 - 0.012 15.8 0.0 0.063 13.6 0.0 2.3 1 1 0 1 1 1 0 AAA domain APS_kinase PF01583.20 CRK42660.1 - 0.18 11.7 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase Aft1_OSA PF11785.8 CRK42678.1 - 4.4 7.8 6.7 0.67 10.4 0.4 2.5 3 0 0 3 3 3 0 Aft1 osmotic stress response (OSM) domain KH_1 PF00013.29 CRK42681.1 - 1.3e-07 31.4 0.1 1.6e-07 31.0 0.1 1.3 1 0 0 1 1 1 1 KH domain Myc_N PF01056.18 CRK42690.1 - 0.021 14.7 0.1 0.023 14.6 0.1 1.0 1 0 0 1 1 1 0 Myc amino-terminal region YL1 PF05764.13 CRK42690.1 - 0.037 14.1 4.7 0.043 13.9 4.7 1.0 1 0 0 1 1 1 0 YL1 nuclear protein Helicase_C PF00271.31 CRK42701.1 - 3.2e-06 27.5 0.1 4.7e-06 26.9 0.1 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Pectinesterase PF01095.19 CRK42701.1 - 0.013 14.2 0.0 0.034 12.9 0.0 1.6 2 0 0 2 2 2 0 Pectinesterase CRM1_C PF08767.11 CRK42706.1 - 3.2e-110 368.3 9.7 3.4e-110 368.2 7.6 1.9 2 0 0 2 2 2 1 CRM1 C terminal Aminotran_5 PF00266.19 CRK42706.1 - 7.9e-14 51.4 0.0 3.7e-13 49.2 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 CRK42706.1 - 0.00021 20.6 0.0 0.00053 19.3 0.0 1.6 1 0 0 1 1 1 1 Aminotransferase class I and II Hemocyanin_M PF00372.19 CRK42706.1 - 0.0016 17.6 0.4 0.016 14.5 0.0 2.5 2 1 1 3 3 3 1 Hemocyanin, copper containing domain MMS19_C PF12460.8 CRK42706.1 - 0.0042 16.3 1.9 0.028 13.5 1.0 2.2 1 1 1 2 2 2 1 RNAPII transcription regulator C-terminal DUF148 PF02520.17 CRK42706.1 - 0.11 12.7 0.3 0.55 10.4 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function DUF148 MCM PF00493.23 CRK42711.1 - 1.7e-58 197.4 1.5 2.2e-58 197.0 1.5 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 CRK42711.1 - 1.1e-24 86.6 0.6 2.3e-24 85.6 0.6 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 CRK42711.1 - 2.6e-08 33.5 0.0 6e-08 32.3 0.0 1.6 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 CRK42711.1 - 0.0002 21.1 0.0 0.00041 20.1 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 CRK42711.1 - 0.0011 18.9 0.1 0.0018 18.2 0.1 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CRK42711.1 - 0.13 12.2 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) CBM_1 PF00734.18 CRK42721.1 - 1.9e-11 43.7 9.2 4.4e-11 42.5 9.2 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Toxin_7 PF05980.12 CRK42721.1 - 0.02 15.1 0.4 0.051 13.8 0.4 1.7 1 0 0 1 1 1 0 Toxin 7 Acid_PPase PF12689.7 CRK42723.1 - 1.9e-60 203.6 0.0 2.3e-60 203.3 0.0 1.1 1 0 0 1 1 1 1 Acid Phosphatase SSXRD PF09514.10 CRK42723.1 - 0.22 11.1 0.0 0.22 11.1 0.0 1.6 2 0 0 2 2 2 0 SSXRD motif HAD PF12710.7 CRK42723.1 - 0.37 11.2 2.7 9.4 6.6 0.1 2.4 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase CRAL_TRIO PF00650.20 CRK42724.1 - 3.6e-23 82.0 0.0 5.2e-23 81.5 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CRK42724.1 - 1.9e-08 34.3 0.0 4.7e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain NmrA PF05368.13 CRK42728.1 - 3.6e-15 56.2 0.0 4.4e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 CRK42728.1 - 3.4e-12 46.6 0.0 5.7e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Shikimate_DH PF01488.20 CRK42728.1 - 0.12 12.4 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short PF00106.25 CRK42730.1 - 8e-33 113.5 0.0 1e-32 113.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK42730.1 - 1.5e-29 103.2 0.1 1.8e-29 103.0 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Glyco_hydro_31 PF01055.26 CRK42732.1 - 3.8e-94 316.4 0.1 4.9e-94 316.0 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 CRK42732.1 - 1.5e-12 47.7 0.0 4.6e-12 46.1 0.0 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like Esterase_phd PF10503.9 CRK42735.1 - 2.3e-17 63.3 0.4 2.3e-17 63.3 0.4 1.6 2 0 0 2 2 2 1 Esterase PHB depolymerase CBM_1 PF00734.18 CRK42735.1 - 2.1e-12 46.8 11.6 8.1e-12 44.9 11.6 2.1 1 0 0 1 1 1 1 Fungal cellulose binding domain Peptidase_S9 PF00326.21 CRK42735.1 - 2.9e-06 26.9 0.5 6.3e-05 22.5 0.5 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family CBM-like PF14683.6 CRK42738.1 - 2.7e-33 115.2 0.0 5.5e-33 114.2 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 CRK42738.1 - 7e-06 25.7 0.2 2.5e-05 24.0 0.2 2.0 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 CRK42738.1 - 1.4e-05 25.3 1.2 0.0053 17.0 0.1 3.3 4 0 0 4 4 4 2 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 CRK42738.1 - 0.082 12.9 0.2 0.72 9.9 0.1 2.4 2 0 0 2 2 2 0 CarboxypepD_reg-like domain SLAC1 PF03595.17 CRK42740.1 - 1.6e-82 277.4 43.7 1.8e-82 277.2 43.7 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Na_Ca_ex PF01699.24 CRK42745.1 - 5e-27 94.7 20.0 5.2e-14 52.4 9.1 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF2206 PF09971.9 CRK42745.1 - 0.022 13.5 0.8 0.55 8.9 0.0 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2206) DUF4337 PF14235.6 CRK42745.1 - 0.095 12.8 1.1 0.26 11.4 0.5 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) MLANA PF14991.6 CRK42745.1 - 0.25 11.6 0.2 3 8.2 0.0 2.6 2 0 0 2 2 2 0 Protein melan-A ETRAMP PF09716.10 CRK42747.1 - 0.059 13.4 0.9 0.35 11.0 0.1 2.3 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Fzo_mitofusin PF04799.13 CRK42747.1 - 0.13 11.8 2.7 0.11 12.0 0.8 1.8 1 1 1 2 2 2 0 fzo-like conserved region Zn_clus PF00172.18 CRK42749.1 - 0.072 13.2 1.9 0.19 11.9 1.9 1.8 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain TauD PF02668.16 CRK42751.1 - 1e-33 117.3 0.1 1.4e-33 116.8 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 CRK42751.1 - 0.079 12.1 0.1 0.14 11.3 0.1 1.3 1 0 0 1 1 1 0 CsiD PALP PF00291.25 CRK42754.1 - 2.9e-61 207.4 2.4 4.8e-61 206.7 2.4 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Peptidase_M20 PF01546.28 CRK42754.1 - 2.9e-24 85.9 0.0 1.1e-23 84.1 0.0 2.0 2 1 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CRK42754.1 - 9e-15 54.5 0.0 2.4e-14 53.2 0.0 1.8 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 CRK42754.1 - 0.00089 19.0 0.2 0.0031 17.2 0.1 1.9 3 0 0 3 3 3 1 Peptidase family M28 SRR1 PF07985.12 CRK42756.1 - 4.1e-06 26.7 0.0 8.8e-06 25.7 0.0 1.6 1 1 0 1 1 1 1 SRR1 MFS_1 PF07690.16 CRK42757.1 - 9.1e-15 54.4 55.9 1.7e-13 50.3 54.7 2.7 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 CRK42757.1 - 3.3e-07 29.1 23.4 4.9e-07 28.6 23.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FUN14 PF04930.15 CRK42757.1 - 1.5 9.3 5.5 4.5 7.8 5.5 1.8 1 0 0 1 1 1 0 FUN14 family Glycos_transf_1 PF00534.20 CRK42760.1 - 1.4e-16 60.5 0.0 2.3e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CRK42760.1 - 2.2e-16 60.5 0.2 5.6e-16 59.2 0.3 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 DUF3492 PF11997.8 CRK42760.1 - 8.4e-07 29.0 0.0 2.9e-06 27.2 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3492) MFS_1 PF07690.16 CRK42762.1 - 1.8e-06 27.1 44.2 4.1e-05 22.7 42.7 2.9 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 CRK42762.1 - 0.00037 19.1 15.3 0.00052 18.6 15.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FUN14 PF04930.15 CRK42762.1 - 0.34 11.4 5.4 0.84 10.1 5.4 1.6 1 0 0 1 1 1 0 FUN14 family Glyco_trans_1_4 PF13692.6 CRK42764.1 - 6e-16 59.1 0.3 1.5e-15 57.8 0.3 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 CRK42764.1 - 2e-15 56.8 0.0 4e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF3492 PF11997.8 CRK42764.1 - 5.2e-06 26.4 0.0 1.6e-05 24.8 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3492) BaxI_1 PF12811.7 CRK42764.1 - 0.022 14.3 1.6 0.069 12.7 1.6 1.8 1 0 0 1 1 1 0 Bax inhibitor 1 like GDP_Man_Dehyd PF16363.5 CRK42766.1 - 7.2e-23 81.5 0.0 1.9e-14 53.9 0.0 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CRK42766.1 - 4.8e-21 75.3 0.0 1.7e-19 70.3 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CRK42766.1 - 1.5e-05 24.1 0.0 0.1 11.6 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 CRK42766.1 - 0.00069 18.8 0.0 0.0091 15.2 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 CRK42766.1 - 0.0019 18.2 0.9 0.24 11.3 0.4 3.1 2 1 0 2 2 2 1 KR domain adh_short PF00106.25 CRK42766.1 - 0.012 15.0 0.0 0.022 14.2 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase NAD_binding_4 PF07993.12 CRK42766.1 - 0.066 12.4 0.0 0.21 10.7 0.0 1.7 2 0 0 2 2 2 0 Male sterility protein Epimerase PF01370.21 CRK42768.1 - 3.1e-29 102.1 0.0 2.5e-28 99.1 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CRK42768.1 - 4.9e-27 95.2 0.0 4.6e-26 92.0 0.0 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 CRK42768.1 - 2.5e-06 26.9 0.0 3.8e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 CRK42768.1 - 0.0054 15.9 0.0 0.0081 15.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 CRK42768.1 - 0.019 14.0 0.0 0.058 12.4 0.0 1.7 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Spherulin4 PF12138.8 CRK42769.1 - 1.5e-72 244.1 0.1 1.5e-72 244.1 0.1 1.6 2 0 0 2 2 1 1 Spherulation-specific family 4 Med15 PF09606.10 CRK42769.1 - 0.0038 16.0 16.9 0.0048 15.7 16.9 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal BRF1 PF07741.13 CRK42769.1 - 0.015 15.6 8.1 0.14 12.5 3.7 2.3 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Connexin PF00029.19 CRK42769.1 - 0.038 13.8 5.5 0.68 9.6 4.0 2.2 2 0 0 2 2 2 0 Connexin Tim54 PF11711.8 CRK42769.1 - 0.042 12.6 8.3 0.079 11.7 5.8 2.0 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Pex16 PF08610.10 CRK42769.1 - 0.059 12.5 0.9 0.11 11.6 0.9 1.4 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) DUF4770 PF15994.5 CRK42769.1 - 0.083 13.1 9.4 0.064 13.5 6.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) Ndc1_Nup PF09531.10 CRK42769.1 - 0.099 11.3 6.3 0.15 10.8 5.8 1.5 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Plasmodium_Vir PF05795.11 CRK42769.1 - 0.12 11.8 2.8 2.4 7.5 0.9 2.1 2 0 0 2 2 2 0 Plasmodium vivax Vir protein GET2 PF08690.10 CRK42769.1 - 0.13 11.9 6.7 0.35 10.5 6.7 1.6 1 0 0 1 1 1 0 GET complex subunit GET2 PIP5K PF01504.18 CRK42769.1 - 0.18 11.0 5.0 0.33 10.1 3.5 1.9 2 0 0 2 2 2 0 Phosphatidylinositol-4-phosphate 5-Kinase PAP_RNA-bind PF04926.15 CRK42769.1 - 0.26 10.9 6.0 0.067 12.8 1.2 2.2 2 0 0 2 2 2 0 Poly(A) polymerase predicted RNA binding domain DUF4746 PF15928.5 CRK42769.1 - 0.38 10.1 8.6 0.13 11.7 1.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) LMBR1 PF04791.16 CRK42769.1 - 0.53 9.1 1.8 0.83 8.5 1.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein GTA_holin_3TM PF11351.8 CRK42769.1 - 0.66 10.5 4.2 1.6 9.3 4.2 1.6 1 0 0 1 1 1 0 Holin of 3TMs, for gene-transfer release CPSF100_C PF13299.6 CRK42769.1 - 0.71 10.0 10.2 2.8 8.1 6.5 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal OATP PF03137.20 CRK42769.1 - 0.76 8.0 2.5 1.3 7.2 2.5 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Rxt3 PF08642.10 CRK42769.1 - 0.87 10.4 5.6 4.3 8.1 3.8 2.5 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 FAM176 PF14851.6 CRK42769.1 - 1.2 8.8 8.8 1.6 8.4 2.5 2.3 2 0 0 2 2 2 0 FAM176 family SpoIIP PF07454.11 CRK42769.1 - 1.6 8.1 15.7 1.1 8.6 11.5 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) CCDC53 PF10152.9 CRK42769.1 - 2.1 8.7 20.2 3.7 7.9 0.1 2.4 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex EMC3_TMCO1 PF01956.16 CRK42769.1 - 2.7 7.7 6.2 5.1 6.8 6.2 1.4 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DDHD PF02862.17 CRK42769.1 - 3.1 7.9 14.7 38 4.3 14.5 2.5 1 1 0 1 1 1 0 DDHD domain EPL1 PF10513.9 CRK42769.1 - 3.2 8.1 14.6 0.045 14.1 4.7 2.3 3 0 0 3 3 2 0 Enhancer of polycomb-like DUF5308 PF17233.2 CRK42769.1 - 3.2 8.0 11.1 0.2 11.9 3.2 2.6 3 0 0 3 3 3 0 Family of unknown function (DUF5308) EOS1 PF12326.8 CRK42769.1 - 3.4 7.6 7.2 1.8 8.5 2.4 2.3 2 1 0 2 2 2 0 N-glycosylation protein PAT1 PF09770.9 CRK42769.1 - 4.9 5.3 18.4 6.6 4.9 18.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PigN PF04987.14 CRK42769.1 - 6 5.6 4.8 11 4.7 4.8 1.3 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) Pex14_N PF04695.13 CRK42769.1 - 7.3 7.2 25.2 0.73 10.5 18.6 2.6 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TERB2 PF15101.6 CRK42769.1 - 7.6 6.5 17.5 18 5.3 15.4 2.2 2 0 0 2 2 2 0 Telomere-associated protein TERB2 Suf PF05843.14 CRK42769.1 - 8.1 6.3 18.5 2.5 8.0 15.6 1.6 2 0 0 2 2 1 0 Suppressor of forked protein (Suf) RPA43_OB PF17875.1 CRK42769.1 - 9.2 6.9 11.0 8.9 7.0 4.2 2.3 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I Glyco_hydro_114 PF03537.13 CRK42771.1 - 2.1e-20 73.1 0.0 2.4e-20 72.8 0.0 1.0 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 Spherulin4 PF12138.8 CRK42775.1 - 1.5e-72 244.1 0.0 1.9e-72 243.8 0.0 1.1 1 0 0 1 1 1 1 Spherulation-specific family 4 SIMPL PF04402.14 CRK42775.1 - 0.014 15.8 0.1 0.021 15.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF541) Glyco_hydro_114 PF03537.13 CRK42777.1 - 2.2e-81 272.6 0.1 2.9e-81 272.2 0.1 1.1 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 Polysacc_deac_1 PF01522.21 CRK42779.1 - 0.011 15.6 0.1 0.029 14.3 0.1 1.6 1 0 0 1 1 1 0 Polysaccharide deacetylase M157 PF11624.8 CRK42779.1 - 0.22 10.8 0.7 6.8 5.9 0.1 2.4 2 0 0 2 2 2 0 MHC class I-like protein M157 Ogr_Delta PF04606.12 CRK42779.1 - 0.49 10.4 3.1 30 4.7 0.2 3.0 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger ABC2_membrane PF01061.24 CRK42780.1 - 1.8e-78 262.8 68.7 2e-42 145.0 23.2 3.0 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 CRK42780.1 - 2.9e-33 115.3 0.0 4.1e-16 59.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 CRK42780.1 - 3e-32 110.4 11.5 1.8e-29 101.5 0.1 3.0 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 CRK42780.1 - 4.3e-12 46.5 0.3 1.4e-11 44.9 0.3 1.9 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 CRK42780.1 - 1.5e-11 44.0 48.7 3.4e-07 29.7 15.1 3.2 2 2 1 3 3 3 2 ABC-2 family transporter protein AAA_16 PF13191.6 CRK42780.1 - 4.3e-06 27.2 0.2 0.0024 18.3 0.1 2.9 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 CRK42780.1 - 5.6e-06 26.4 0.0 1.2e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 CRK42780.1 - 6.3e-06 26.2 0.0 0.042 13.7 0.0 2.9 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 CRK42780.1 - 3.6e-05 23.4 0.1 0.01 15.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CRK42780.1 - 7.9e-05 22.8 0.0 0.037 14.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CRK42780.1 - 0.00012 22.6 0.0 0.0022 18.5 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.6 CRK42780.1 - 0.00018 21.8 0.1 0.025 14.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 CRK42780.1 - 0.00025 20.7 0.1 0.12 12.0 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 CRK42780.1 - 0.00028 20.6 0.0 0.021 14.6 0.0 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain NACHT PF05729.12 CRK42780.1 - 0.0011 18.9 0.1 0.12 12.3 0.1 2.5 2 0 0 2 2 2 1 NACHT domain AAA_23 PF13476.6 CRK42780.1 - 0.0022 18.5 2.6 0.022 15.3 0.0 3.0 4 0 0 4 4 3 1 AAA domain MMR_HSR1 PF01926.23 CRK42780.1 - 0.0028 17.7 0.0 0.16 12.1 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_17 PF13207.6 CRK42780.1 - 0.0035 17.8 0.0 0.14 12.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 CRK42780.1 - 0.0051 17.1 2.2 0.0076 16.5 0.1 2.4 3 0 0 3 3 3 1 AAA domain TsaE PF02367.17 CRK42780.1 - 0.011 15.7 0.1 0.25 11.4 0.2 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 CRK42780.1 - 0.014 15.8 2.7 1.7 9.1 0.0 3.1 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 CRK42780.1 - 0.02 14.6 0.1 0.47 10.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CRK42780.1 - 0.027 14.9 0.0 4.6 7.7 0.0 2.6 2 0 0 2 2 2 0 RNA helicase T2SSE PF00437.20 CRK42780.1 - 0.04 13.0 0.0 2 7.4 0.1 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_19 PF13245.6 CRK42780.1 - 0.041 14.2 0.0 14 6.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain dNK PF01712.19 CRK42780.1 - 0.044 13.6 0.0 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_24 PF13479.6 CRK42780.1 - 0.1 12.3 0.0 0.99 9.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain Pantoate_ligase PF02569.15 CRK42780.1 - 0.11 11.7 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 Pantoate-beta-alanine ligase FtsK_SpoIIIE PF01580.18 CRK42780.1 - 0.12 11.7 0.0 9.8 5.4 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF1631 PF07793.11 CRK42780.1 - 3 6.2 10.1 5.5 5.3 10.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) NUC153 PF08159.12 CRK42784.1 - 1.2e-14 53.7 0.2 1.2e-14 53.7 0.2 4.0 4 0 0 4 4 4 2 NUC153 domain muHD PF10291.9 CRK42789.1 - 4.5e-69 232.8 0.0 6.9e-69 232.2 0.0 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.23 CRK42789.1 - 1.7e-06 28.2 0.1 1.7e-06 28.2 0.1 2.2 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain BAR_3 PF16746.5 CRK42789.1 - 0.86 9.3 4.1 0.28 10.9 1.2 1.6 2 0 0 2 2 2 0 BAR domain of APPL family Peptidase_M35 PF02102.15 CRK42791.1 - 8.8e-77 258.4 14.6 1.1e-76 258.1 14.6 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 CRK42791.1 - 3e-39 134.8 6.1 3e-39 134.8 6.1 1.5 2 0 0 2 2 2 1 Lysine-specific metallo-endopeptidase MFS_1 PF07690.16 CRK42793.1 - 7.5e-32 110.6 41.5 7.5e-32 110.6 41.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily NAD_binding_1 PF00175.21 CRK42796.1 - 1.4e-23 83.6 0.0 2.2e-23 83.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 CRK42796.1 - 4.7e-07 30.0 0.0 0.0043 17.2 0.0 2.1 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_6 PF00970.24 CRK42796.1 - 3.4e-05 24.1 0.0 9.7e-05 22.7 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain WW PF00397.26 CRK42797.1 - 4.3e-14 52.3 3.5 9.2e-14 51.2 3.5 1.6 1 0 0 1 1 1 1 WW domain CDC45 PF02724.14 CRK42797.1 - 0.23 9.7 5.7 0.25 9.6 5.7 1.1 1 0 0 1 1 1 0 CDC45-like protein ABC2_membrane PF01061.24 CRK42800.1 - 1.9e-82 275.7 62.6 7.2e-43 146.5 25.5 3.7 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.12 CRK42800.1 - 1.9e-36 123.8 6.1 1.5e-30 105.0 0.0 3.3 3 0 0 3 3 2 2 CDR ABC transporter ABC_tran PF00005.27 CRK42800.1 - 2.7e-36 125.1 0.0 9.5e-17 61.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.6 CRK42800.1 - 3.5e-19 69.2 0.1 8.9e-19 67.9 0.1 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 CRK42800.1 - 3.7e-06 26.3 17.5 3.7e-06 26.3 17.5 3.2 2 1 1 3 3 2 1 ABC-2 family transporter protein AAA_16 PF13191.6 CRK42800.1 - 4.6e-06 27.1 0.1 0.00085 19.7 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 CRK42800.1 - 8.4e-06 25.5 0.2 0.0043 16.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 CRK42800.1 - 3.1e-05 24.0 0.2 0.0052 16.7 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 CRK42800.1 - 5.7e-05 23.3 0.2 0.0094 16.1 0.1 2.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CRK42800.1 - 0.00021 21.8 0.1 0.0078 16.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CRK42800.1 - 0.00045 19.9 0.9 0.055 13.2 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 CRK42800.1 - 0.0018 18.6 1.0 1.5 9.1 0.2 2.8 2 1 0 2 2 2 2 AAA domain cobW PF02492.19 CRK42800.1 - 0.0022 17.6 1.1 0.051 13.2 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 CRK42800.1 - 0.0024 18.3 0.1 0.69 10.3 0.0 2.7 2 0 0 2 2 2 1 RNA helicase NACHT PF05729.12 CRK42800.1 - 0.0081 16.1 0.9 2.2 8.2 0.2 2.6 2 0 0 2 2 2 1 NACHT domain AAA_21 PF13304.6 CRK42800.1 - 0.0096 15.8 0.0 1.3 8.8 0.0 2.7 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 CRK42800.1 - 0.019 14.7 1.0 2.2 7.9 0.5 2.4 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 CRK42800.1 - 0.024 14.7 0.1 7.4 6.7 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase SMC_N PF02463.19 CRK42800.1 - 0.039 13.4 0.2 3.2 7.1 0.0 3.0 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_17 PF13207.6 CRK42800.1 - 0.047 14.1 0.2 1.3 9.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 CRK42800.1 - 0.056 13.4 0.3 0.52 10.2 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 dNK PF01712.19 CRK42800.1 - 0.19 11.6 0.0 1.8 8.3 0.0 2.1 2 0 0 2 2 2 0 Deoxynucleoside kinase A_deaminase PF00962.22 CRK42802.1 - 6.4e-35 121.0 0.0 8e-35 120.7 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase MFS_1 PF07690.16 CRK42804.1 - 2.7e-31 108.8 27.9 3.7e-31 108.3 27.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 CRK42804.1 - 5.3e-06 26.0 4.8 5.3e-06 26.0 4.8 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB MFS_1 PF07690.16 CRK42805.1 - 5.8e-15 55.1 34.4 2.7e-11 43.0 13.2 3.0 1 1 2 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 CRK42805.1 - 0.00068 18.2 0.2 0.0017 16.8 0.1 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) NPP1 PF05630.11 CRK42807.1 - 2e-42 145.6 5.9 7.2e-42 143.7 5.9 1.7 1 1 0 1 1 1 1 Necrosis inducing protein (NPP1) DUF2196 PF09962.9 CRK42809.1 - 2.2e-23 82.0 2.9 3.2e-23 81.5 2.9 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2196) Exo5 PF09810.9 CRK42811.1 - 7e-140 466.7 0.0 8.3e-140 466.4 0.0 1.1 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.7 CRK42811.1 - 0.0006 19.8 0.6 1.9 8.3 0.0 3.0 2 1 0 2 2 2 2 PD-(D/E)XK nuclease superfamily Hexokinase_2 PF03727.16 CRK42815.1 - 2.4e-48 164.7 0.0 3.1e-48 164.3 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 CRK42815.1 - 4.9e-46 157.2 0.0 6.8e-46 156.7 0.0 1.2 1 0 0 1 1 1 1 Hexokinase GILT PF03227.16 CRK42817.1 - 1.6e-17 63.7 0.0 2.6e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) DcpS_C PF11969.8 CRK42818.1 - 3.4e-32 111.3 0.0 5.4e-32 110.7 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.12 CRK42818.1 - 2.6e-20 73.2 0.0 6.2e-20 72.0 0.0 1.6 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal Pyridox_oxase_2 PF12766.7 CRK42820.1 - 1.5e-14 54.4 0.0 2.1e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF1180 PF06679.12 CRK42822.1 - 0.071 13.5 0.5 0.58 10.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) DUF5305 PF17231.2 CRK42822.1 - 0.19 11.1 0.0 0.5 9.7 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Nop25 PF09805.9 CRK42822.1 - 2.3 8.7 9.8 0.5 10.8 6.2 1.8 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) WD40 PF00400.32 CRK42843.1 - 0.0008 20.2 0.1 0.5 11.3 0.0 2.9 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK42843.1 - 0.0064 16.8 0.0 0.031 14.6 0.0 1.9 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Lactonase PF10282.9 CRK42843.1 - 0.11 11.8 0.0 0.63 9.2 0.0 1.9 1 1 1 2 2 2 0 Lactonase, 7-bladed beta-propeller Ribosomal_S2 PF00318.20 CRK42844.1 - 2.3e-19 69.5 0.0 1.7e-15 56.8 0.0 2.0 1 1 1 2 2 2 2 Ribosomal protein S2 ADH_zinc_N PF00107.26 CRK42847.1 - 3.7e-15 56.0 0.0 4.9e-15 55.7 0.0 1.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 CRK42847.1 - 2.5e-05 23.7 0.1 3.6e-05 23.2 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 CRK42847.1 - 0.0056 16.3 0.0 0.0081 15.8 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.21 CRK42847.1 - 0.0091 15.3 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Glyco_hydro_43 PF04616.14 CRK42847.1 - 0.18 11.1 0.0 0.35 10.1 0.0 1.4 2 0 0 2 2 2 0 Glycosyl hydrolases family 43 p450 PF00067.22 CRK42855.1 - 1e-13 50.9 0.0 1.1e-13 50.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Biotin_lipoyl PF00364.22 CRK42858.1 - 2.7e-18 65.6 2.1 4.3e-18 64.9 2.1 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 CRK42858.1 - 2.5e-10 40.0 1.1 6.2e-06 25.9 0.1 2.4 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.6 CRK42858.1 - 0.00011 22.8 0.1 0.033 14.9 0.0 2.4 2 1 0 2 2 2 1 HlyD family secretion protein HlyD_D23 PF16576.5 CRK42858.1 - 0.0018 17.5 0.5 0.34 10.1 0.0 2.4 2 1 1 3 3 3 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion Peptidase_M23 PF01551.22 CRK42858.1 - 0.004 17.3 0.1 1.1 9.5 0.0 2.8 1 1 1 3 3 3 1 Peptidase family M23 RnfC_N PF13375.6 CRK42858.1 - 0.0056 16.6 0.3 0.012 15.5 0.3 1.6 2 0 0 2 2 2 1 RnfC Barrel sandwich hybrid domain PYNP_C PF07831.13 CRK42858.1 - 0.0074 15.9 0.0 0.16 11.6 0.0 2.2 2 0 0 2 2 2 1 Pyrimidine nucleoside phosphorylase C-terminal domain QRPTase_N PF02749.16 CRK42858.1 - 0.015 15.4 0.2 1 9.5 0.0 2.9 2 1 1 3 3 3 0 Quinolinate phosphoribosyl transferase, N-terminal domain NQRA PF05896.11 CRK42858.1 - 0.017 14.5 0.3 0.026 14.0 0.3 1.4 1 1 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) DUF2118 PF09891.9 CRK42858.1 - 0.02 14.9 0.0 0.044 13.7 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) HlyD_2 PF12700.7 CRK42858.1 - 0.036 12.8 0.0 0.065 12.0 0.0 1.4 1 1 0 1 1 1 0 HlyD family secretion protein GCV_H PF01597.19 CRK42858.1 - 0.08 12.8 0.2 0.16 11.9 0.2 1.5 1 0 0 1 1 1 0 Glycine cleavage H-protein PTS_EIIA_1 PF00358.20 CRK42858.1 - 0.099 12.4 0.1 3.1 7.5 0.0 2.5 1 1 1 2 2 2 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 2-Hacid_dh PF00389.30 CRK42862.1 - 0.00046 19.8 0.0 0.00052 19.7 0.0 1.2 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Mito_carr PF00153.27 CRK42880.1 - 7.7e-20 70.6 0.4 4.8e-09 36.0 0.0 2.2 2 0 0 2 2 2 2 Mitochondrial carrier protein Glyco_hydro_47 PF01532.20 CRK42880.1 - 0.0009 18.2 0.3 0.0012 17.8 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Wzy_C PF04932.15 CRK42880.1 - 0.029 14.0 0.0 4.1 7.0 0.0 2.1 1 1 1 2 2 2 0 O-Antigen ligase Med25_SD1 PF11235.8 CRK42880.1 - 0.15 12.4 0.9 11 6.3 0.1 2.1 2 0 0 2 2 2 0 Mediator complex subunit 25 synapsin 1 Colicin_V PF02674.16 CRK42880.1 - 0.35 10.9 3.3 3.5 7.6 3.3 2.1 1 1 0 1 1 1 0 Colicin V production protein Lyase_1 PF00206.20 CRK42884.1 - 1.8e-36 126.2 0.0 2e-36 126.0 0.0 1.1 1 0 0 1 1 1 1 Lyase NAD_binding_10 PF13460.6 CRK42892.1 - 1.7e-15 57.4 1.1 2.2e-15 57.0 0.1 1.7 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 CRK42892.1 - 8.7e-15 54.9 0.0 1.1e-14 54.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Fer4 PF00037.27 CRK42892.1 - 1.6e-13 49.9 16.4 1.2e-07 31.2 3.6 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 CRK42892.1 - 1.3e-12 48.1 10.7 2.2e-12 47.3 10.7 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 CRK42892.1 - 4e-09 37.3 8.7 0.00047 21.0 1.7 2.6 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 CRK42892.1 - 1.9e-08 34.3 31.8 9.7e-06 25.6 12.3 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_9 PF13187.6 CRK42892.1 - 5.2e-08 32.9 10.1 9.9e-08 32.0 10.1 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 CRK42892.1 - 8e-08 32.3 21.6 2.2e-06 27.7 12.2 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 CRK42892.1 - 2.7e-06 27.2 16.9 0.00042 20.3 5.3 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 CRK42892.1 - 3.7e-06 26.7 12.2 0.0057 16.7 3.2 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.6 CRK42892.1 - 2.3e-05 24.7 11.3 0.00034 21.0 11.9 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_4 PF12800.7 CRK42892.1 - 0.00017 21.8 12.7 0.0024 18.2 2.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Semialdhyde_dh PF01118.24 CRK42892.1 - 0.00021 21.7 0.0 0.00053 20.4 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 CRK42892.1 - 0.00061 19.9 0.0 0.0013 18.8 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Fer4_17 PF13534.6 CRK42892.1 - 0.0012 19.3 12.7 0.059 13.9 13.2 2.4 1 1 2 3 3 3 3 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.10 CRK42892.1 - 0.032 14.5 5.8 1.1 9.5 0.3 2.3 1 1 1 2 2 2 0 c-SKI Smad4 binding domain NAD_binding_4 PF07993.12 CRK42892.1 - 0.069 12.3 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein Fer4_18 PF13746.6 CRK42892.1 - 0.1 12.8 9.3 1 9.6 1.6 2.5 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 CRK42892.1 - 0.13 12.9 13.9 1.6 9.3 4.0 2.9 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I ETF_QO PF05187.13 CRK42892.1 - 0.19 11.8 5.0 0.56 10.4 0.3 2.3 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_3 PF12798.7 CRK42892.1 - 0.32 12.0 16.6 0.82 10.8 3.3 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_22 PF17179.4 CRK42892.1 - 1.4 9.8 11.7 4.9 8.1 1.5 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain adh_short PF00106.25 CRK42895.1 - 5.6e-28 97.7 0.0 6.9e-21 74.6 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CRK42895.1 - 7.4e-16 58.4 0.0 2.3e-13 50.3 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK42895.1 - 2.7e-10 40.4 0.0 3.9e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 KR domain Goodbye PF17109.5 CRK42897.1 - 7.2e-32 110.4 0.7 2.4e-31 108.7 0.7 1.9 1 0 0 1 1 1 1 fungal STAND N-terminal Goodbye domain TPR_12 PF13424.6 CRK42897.1 - 1.5e-11 44.4 19.5 8.9e-06 25.9 0.4 6.4 6 1 0 6 6 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 CRK42897.1 - 4.8e-11 42.0 10.7 0.004 16.9 0.0 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 CRK42897.1 - 6.5e-09 35.2 24.1 0.0018 18.3 0.0 6.3 7 0 0 7 7 4 4 Tetratricopeptide repeat AAA_22 PF13401.6 CRK42897.1 - 1.9e-06 28.2 0.0 2e-05 24.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain TPR_7 PF13176.6 CRK42897.1 - 3.1e-06 26.8 12.3 0.17 12.0 0.2 6.2 5 0 0 5 5 5 2 Tetratricopeptide repeat AAA_16 PF13191.6 CRK42897.1 - 7.8e-06 26.4 0.0 5.1e-05 23.7 0.0 2.5 1 0 0 1 1 1 1 AAA ATPase domain TPR_19 PF14559.6 CRK42897.1 - 7.8e-06 26.3 20.2 0.04 14.4 0.1 5.9 6 1 1 7 7 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 CRK42897.1 - 3.2e-05 23.8 9.6 0.53 10.6 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 CRK42897.1 - 0.00017 21.4 15.5 0.033 14.1 0.3 7.0 7 0 0 7 7 7 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CRK42897.1 - 0.003 17.7 7.1 0.64 10.3 0.0 3.5 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 NACHT PF05729.12 CRK42897.1 - 0.0041 17.1 0.1 0.029 14.3 0.0 2.3 2 0 0 2 2 2 1 NACHT domain IstB_IS21 PF01695.17 CRK42897.1 - 0.014 15.1 0.0 0.038 13.7 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein TPR_6 PF13174.6 CRK42897.1 - 0.021 15.4 7.5 10 7.0 0.0 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat AAA_33 PF13671.6 CRK42897.1 - 0.048 13.8 0.2 0.58 10.3 0.0 3.0 3 0 0 3 3 3 0 AAA domain Foie-gras_1 PF11817.8 CRK42897.1 - 0.068 12.8 0.5 1.3 8.6 0.0 2.6 2 1 0 2 2 2 0 Foie gras liver health family 1 RNA_helicase PF00910.22 CRK42897.1 - 0.097 13.1 0.1 2.9 8.3 0.0 2.9 3 0 0 3 3 2 0 RNA helicase PPR PF01535.20 CRK42897.1 - 0.5 10.7 5.1 67 4.1 0.1 5.4 6 0 0 6 6 5 0 PPR repeat TPR_4 PF07721.14 CRK42897.1 - 0.56 11.0 21.1 8.3 7.4 0.3 6.3 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 CRK42897.1 - 0.78 10.3 10.7 1.7 9.2 0.5 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-RING_2 PF13639.6 CRK42897.1 - 0.85 10.0 5.4 2.1 8.8 5.4 1.7 1 0 0 1 1 1 0 Ring finger domain TPR_14 PF13428.6 CRK42897.1 - 7.6 7.6 26.7 1.9 9.5 0.2 8.9 7 3 3 10 10 9 0 Tetratricopeptide repeat Thioredoxin_6 PF13848.6 CRK42898.1 - 3.8e-10 40.0 0.0 1.3e-09 38.2 0.0 1.8 1 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin PF00085.20 CRK42898.1 - 5.5e-08 32.7 0.0 2.6e-07 30.6 0.0 2.1 2 1 0 2 2 2 1 Thioredoxin 2OG-FeII_Oxy_3 PF13640.6 CRK42899.1 - 1.9e-09 38.3 0.0 3.4e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Helicase_C_2 PF13307.6 CRK42900.1 - 1e-57 195.0 0.0 2.3e-57 193.9 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 CRK42900.1 - 7.5e-47 159.2 0.0 1.2e-46 158.5 0.0 1.3 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 CRK42900.1 - 0.00097 19.2 0.1 0.084 12.9 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CRK42900.1 - 0.14 11.9 1.2 1.4 8.6 1.2 2.4 1 1 0 1 1 1 0 DEAD/DEAH box helicase PhoH PF02562.16 CRK42900.1 - 0.14 11.6 0.1 4.5 6.7 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein Ribosomal_L27A PF00828.19 CRK42901.1 - 1.1e-18 68.2 0.2 2.6e-18 66.9 0.2 1.7 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Pkinase PF00069.25 CRK42904.1 - 2.9e-40 138.3 0.0 1.8e-39 135.7 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK42904.1 - 1.9e-14 53.6 0.0 1e-09 38.0 0.0 2.8 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 CRK42904.1 - 0.0003 20.8 0.0 0.027 14.4 0.0 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CRK42904.1 - 0.0085 14.9 0.0 0.012 14.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CRK42904.1 - 0.078 12.3 0.0 5.8 6.1 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 CRK42904.1 - 0.15 11.4 0.0 8.2 5.7 0.0 2.5 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cnd1_N PF12922.7 CRK42905.1 - 1.4e-63 213.7 0.1 1e-62 210.8 0.1 2.3 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.7 CRK42905.1 - 4e-47 160.3 6.4 7.1e-44 149.7 0.1 3.6 5 0 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CRK42905.1 - 5.5e-10 39.5 0.4 0.00055 20.3 0.1 4.0 2 1 1 3 3 3 2 HEAT repeats HEAT PF02985.22 CRK42905.1 - 2.6e-08 33.4 9.3 0.012 15.8 0.0 5.7 5 0 0 5 5 4 2 HEAT repeat HEAT_EZ PF13513.6 CRK42905.1 - 1.4e-05 25.4 3.0 0.037 14.6 0.2 4.0 3 0 0 3 3 3 1 HEAT-like repeat Adaptin_N PF01602.20 CRK42905.1 - 5.5e-05 21.9 2.0 0.012 14.1 0.1 2.8 2 1 0 2 2 2 2 Adaptin N terminal region RTP1_C1 PF10363.9 CRK42905.1 - 0.00027 21.1 0.2 0.17 12.1 0.0 3.7 3 1 1 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 Cnd3 PF12719.7 CRK42905.1 - 0.0061 15.8 2.3 0.0061 15.8 2.3 3.2 3 2 1 4 4 4 1 Nuclear condensing complex subunits, C-term domain DUF5445 PF17520.2 CRK42905.1 - 0.051 13.4 0.0 1.5 8.7 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5445) Ald_Xan_dh_C2 PF02738.18 CRK42905.1 - 0.19 10.1 0.0 0.35 9.3 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin-binding domain of aldehyde dehydrogenase DUF2408 PF10303.9 CRK42905.1 - 0.31 11.6 2.3 3.4 8.2 0.3 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2408) GRIM-19 PF06212.12 CRK42907.1 - 5.2e-24 84.7 0.1 2.3e-23 82.6 0.1 1.7 1 1 0 1 1 1 1 GRIM-19 protein NYN PF01936.18 CRK42908.1 - 2.6e-30 105.8 0.0 4.3e-30 105.1 0.0 1.3 1 0 0 1 1 1 1 NYN domain OST-HTH PF12872.7 CRK42908.1 - 1.4e-15 56.8 0.0 2.6e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 OST-HTH/LOTUS domain Fe-S_assembly PF04384.13 CRK42908.1 - 0.00063 20.3 0.0 0.0011 19.5 0.0 1.4 1 0 0 1 1 1 1 Iron-sulphur cluster assembly p450 PF00067.22 CRK42909.1 - 1.9e-09 36.8 0.0 1.9e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 GRAM PF02893.20 CRK42911.1 - 1.7e-31 108.4 2.6 2e-19 69.5 0.0 3.4 3 0 0 3 3 3 3 GRAM domain Glyco_transf_28 PF03033.20 CRK42911.1 - 1.3e-29 103.0 0.0 4.9e-29 101.1 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain PH PF00169.29 CRK42911.1 - 4.4e-13 49.7 0.0 2.9e-12 47.0 0.0 2.4 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 CRK42911.1 - 4e-05 24.0 0.4 0.00087 19.7 0.4 2.7 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 CRK42911.1 - 9.2e-05 22.7 0.0 0.00022 21.5 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain UDPGT PF00201.18 CRK42911.1 - 0.002 17.0 0.0 0.0048 15.8 0.0 1.6 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase WD40 PF00400.32 CRK42912.1 - 3.1e-08 34.1 5.8 0.025 15.5 0.1 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat Pectate_lyase PF03211.13 CRK42916.1 - 1.2e-76 256.8 9.4 1.6e-76 256.4 9.4 1.1 1 0 0 1 1 1 1 Pectate lyase MFS_1 PF07690.16 CRK42917.1 - 1.1e-44 152.8 40.2 1.1e-44 152.8 40.2 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK42917.1 - 8.7e-12 44.6 16.1 8.7e-12 44.6 16.1 2.5 3 0 0 3 3 3 2 Sugar (and other) transporter Adeno_E4_34 PF04528.13 CRK42917.1 - 0.081 12.8 0.3 0.28 11.0 0.3 1.8 2 0 0 2 2 2 0 Adenovirus early E4 34 kDa protein conserved region ketoacyl-synt PF00109.26 CRK42919.1 - 6.4e-80 268.4 0.0 1.2e-79 267.5 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 CRK42919.1 - 2.1e-47 162.2 0.1 3.5e-47 161.5 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 CRK42919.1 - 6.6e-20 71.5 0.0 1.1e-19 70.9 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase SAT PF16073.5 CRK42919.1 - 7.5e-20 71.7 1.4 1.6e-16 60.8 0.0 3.4 2 1 0 2 2 2 2 Starter unit:ACP transacylase in aflatoxin biosynthesis PP-binding PF00550.25 CRK42919.1 - 1e-19 70.6 4.1 9e-09 35.6 0.6 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site Thioesterase PF00975.20 CRK42919.1 - 7.9e-17 62.1 0.0 3.7e-16 59.9 0.0 2.2 3 0 0 3 3 3 1 Thioesterase domain KAsynt_C_assoc PF16197.5 CRK42919.1 - 1.7e-09 38.1 0.0 4e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Abhydrolase_6 PF12697.7 CRK42919.1 - 1.1e-05 26.2 0.2 0.00042 21.0 0.0 2.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Thiolase_N PF00108.23 CRK42919.1 - 0.0005 19.5 0.0 0.001 18.5 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Abhydrolase_3 PF07859.13 CRK42919.1 - 0.0065 16.3 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Trp_halogenase PF04820.14 CRK42919.1 - 0.12 11.2 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase AMP-binding PF00501.28 CRK42920.1 - 5.8e-34 117.4 0.0 2e-33 115.7 0.0 1.7 1 1 1 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.12 CRK42920.1 - 4.7e-16 58.7 0.0 8.2e-16 57.9 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 CRK42920.1 - 1.8e-06 27.6 0.0 3.7e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 CRK42920.1 - 0.00069 19.9 0.0 0.0033 17.8 0.0 2.2 1 1 0 1 1 1 1 Phosphopantetheine attachment site Semialdhyde_dh PF01118.24 CRK42920.1 - 0.019 15.4 0.0 0.043 14.3 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 CRK42920.1 - 0.068 13.1 0.6 0.18 11.7 0.1 2.0 2 0 0 2 2 2 0 KR domain adh_short PF00106.25 CRK42921.1 - 1.3e-39 135.7 0.1 1.8e-39 135.3 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CRK42921.1 - 1.1e-26 93.9 0.3 1.4e-26 93.5 0.3 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CRK42921.1 - 2.9e-06 27.3 0.2 4e-06 26.8 0.2 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 CRK42921.1 - 0.00091 18.7 0.0 0.0014 18.1 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 CRK42921.1 - 0.03 13.8 0.1 0.049 13.1 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Myb_DNA-binding PF00249.31 CRK42922.1 - 3e-36 123.3 17.1 9.3e-16 57.8 0.4 4.2 3 1 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CRK42922.1 - 4.7e-29 100.4 12.1 4.6e-15 55.6 0.7 4.1 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 CRK42922.1 - 2.1e-08 34.0 2.8 0.00042 20.2 0.0 2.9 3 0 0 3 3 3 2 Myb DNA-binding like SANT_DAMP1_like PF16282.5 CRK42922.1 - 4.6e-06 26.7 2.0 0.048 13.8 0.1 2.7 2 1 1 3 3 3 2 SANT/Myb-like domain of DAMP1 MADF_DNA_bdg PF10545.9 CRK42922.1 - 0.0026 18.1 3.1 1 9.7 0.3 2.4 2 0 0 2 2 2 2 Alcohol dehydrogenase transcription factor Myb/SANT-like Rap1_C PF11626.8 CRK42922.1 - 0.0072 16.4 0.9 2.4 8.3 0.2 3.1 2 1 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain SLIDE PF09111.10 CRK42922.1 - 0.014 15.4 0.1 12 5.9 0.0 3.5 2 1 1 3 3 3 0 SLIDE Methyltransf_2 PF00891.18 CRK42924.1 - 1.2e-26 93.3 0.0 5.5e-26 91.2 0.0 1.9 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_31 PF13847.6 CRK42924.1 - 0.0022 17.8 0.0 0.0035 17.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK42924.1 - 0.018 15.7 0.0 0.037 14.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Dimerisation2 PF16864.5 CRK42924.1 - 0.17 11.9 0.0 0.61 10.1 0.0 1.8 2 0 0 2 2 2 0 Dimerisation domain FAD_binding_3 PF01494.19 CRK42925.1 - 1.1e-65 222.2 0.0 6.8e-65 219.6 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 CRK42925.1 - 0.0025 18.0 0.0 0.0092 16.2 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CRK42925.1 - 0.0039 16.5 0.0 0.0065 15.7 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 CRK42925.1 - 0.0056 15.8 0.2 0.051 12.6 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 CRK42925.1 - 0.0071 15.6 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 CRK42925.1 - 0.0092 15.1 1.7 0.017 14.2 0.3 1.9 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 CRK42925.1 - 0.012 14.3 0.1 0.017 13.8 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 CRK42925.1 - 0.013 14.7 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Phe_hydrox_dim PF07976.12 CRK42925.1 - 0.014 15.4 0.0 0.026 14.6 0.0 1.4 1 0 0 1 1 1 0 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.24 CRK42925.1 - 0.022 14.3 0.6 0.097 12.2 0.6 2.1 1 1 0 1 1 1 0 FAD dependent oxidoreductase FAD_oxidored PF12831.7 CRK42925.1 - 0.025 13.9 0.1 0.038 13.3 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 CRK42925.1 - 0.076 13.6 0.0 0.17 12.5 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Abhydrolase_6 PF12697.7 CRK42927.1 - 2.1e-11 44.8 1.1 3.2e-11 44.3 1.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CRK42927.1 - 7.9e-08 32.3 0.1 1.4e-07 31.4 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CRK42927.1 - 9.2e-08 31.6 0.0 2.1e-07 30.5 0.0 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF676 PF05057.14 CRK42927.1 - 0.019 14.5 0.0 0.025 14.1 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DLH PF01738.18 CRK42927.1 - 0.025 14.1 0.0 0.21 11.1 0.0 2.0 2 0 0 2 2 2 0 Dienelactone hydrolase family LIP PF03583.14 CRK42927.1 - 0.031 13.6 0.0 0.053 12.8 0.0 1.3 1 0 0 1 1 1 0 Secretory lipase Peptidase_S15 PF02129.18 CRK42927.1 - 0.036 13.6 0.0 0.052 13.1 0.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.16 CRK42927.1 - 0.04 13.7 0.0 0.089 12.6 0.0 1.6 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase FAD_binding_4 PF01565.23 CRK42928.1 - 6.2e-24 84.3 0.7 9.5e-24 83.7 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain Methyltransf_23 PF13489.6 CRK42929.1 - 2e-24 86.3 0.0 2.9e-24 85.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CRK42929.1 - 1.1e-08 35.7 0.0 2.5e-08 34.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CRK42929.1 - 2.3e-07 31.5 0.0 1e-06 29.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CRK42929.1 - 2.3e-06 28.2 0.0 4.8e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CRK42929.1 - 7.1e-06 25.9 0.0 0.00015 21.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 CRK42929.1 - 7.4e-05 22.3 0.0 0.00011 21.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 CRK42929.1 - 0.049 13.4 0.1 1.5 8.5 0.1 2.2 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 CRK42929.1 - 0.11 11.8 0.0 0.96 8.7 0.0 2.1 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 CRK42929.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Aldo_ket_red PF00248.21 CRK42932.1 - 2.7e-66 223.8 0.0 3.3e-66 223.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Ribonuc_red_2_N PF08471.10 CRK42932.1 - 0.064 13.4 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 Class II vitamin B12-dependent ribonucleotide reductase FAD_binding_4 PF01565.23 CRK42933.1 - 3.9e-19 68.8 0.8 9.2e-19 67.6 0.8 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 CRK42933.1 - 4.8e-14 52.2 0.1 9.5e-14 51.2 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like FAD-oxidase_C PF02913.19 CRK42933.1 - 0.13 11.9 0.0 0.45 10.1 0.0 1.9 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain Lactonase PF10282.9 CRK42935.1 - 1.2e-59 202.3 0.0 1e-57 196.0 0.0 2.0 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller NRIP1_repr_3 PF15689.5 CRK42935.1 - 0.21 11.9 0.1 37 4.7 0.1 2.4 2 0 0 2 2 2 0 Nuclear receptor-interacting protein 1 repression 3 Glyco_hydro_114 PF03537.13 CRK42937.1 - 1.1e-86 290.0 0.1 1.2e-86 289.8 0.1 1.0 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 p450 PF00067.22 CRK42939.1 - 1e-36 126.7 0.0 1.1e-36 126.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CFEM PF05730.11 CRK42942.1 - 2.1e-12 46.9 12.4 4.7e-12 45.8 12.4 1.6 1 0 0 1 1 1 1 CFEM domain Gamma-thionin PF00304.20 CRK42942.1 - 0.24 11.7 6.5 0.087 13.1 2.7 2.2 2 0 0 2 2 2 0 Gamma-thionin family FAD_binding_4 PF01565.23 CRK42944.1 - 2.6e-22 79.1 2.4 7e-22 77.7 2.4 1.8 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 CRK42944.1 - 3.8e-09 36.5 1.2 3.8e-09 36.5 1.2 1.8 2 0 0 2 2 2 1 Berberine and berberine like C2 PF00168.30 CRK42949.1 - 2.4e-12 47.0 0.0 5.2e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 C2 domain CTP_transf_like PF01467.26 CRK42953.1 - 8.5e-20 71.4 0.0 1.1e-19 71.1 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like Peptidase_C12 PF01088.21 CRK42954.1 - 6.7e-47 160.0 0.0 1e-46 159.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 FMO-like PF00743.19 CRK42954.1 - 9.1e-13 47.5 0.0 3.2e-11 42.4 0.0 2.2 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.6 CRK42954.1 - 8.8e-10 38.8 0.5 6e-08 32.8 0.2 3.3 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 CRK42954.1 - 5e-09 35.8 1.2 8.8e-08 31.7 0.1 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase 7tm_2 PF00002.24 CRK42954.1 - 6.5e-08 32.2 13.8 6.5e-08 32.2 13.8 1.4 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) NAD_binding_8 PF13450.6 CRK42954.1 - 5.2e-07 29.8 0.6 2e-06 27.9 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 CRK42954.1 - 3.6e-06 26.4 0.0 6.3e-05 22.3 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 CRK42954.1 - 1.4e-05 24.6 0.1 0.07 12.4 0.0 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Git3 PF11710.8 CRK42954.1 - 3.2e-05 23.8 13.7 5.2e-05 23.1 13.7 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Dicty_CAR PF05462.11 CRK42954.1 - 5.4e-05 22.5 12.5 0.00011 21.5 12.5 1.4 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Amino_oxidase PF01593.24 CRK42954.1 - 0.00013 21.4 0.0 0.019 14.3 0.0 2.5 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.24 CRK42954.1 - 0.00044 19.9 0.7 0.055 13.0 0.1 3.0 2 1 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 CRK42954.1 - 0.0044 16.3 0.0 0.0081 15.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 CRK42954.1 - 0.016 13.9 0.0 0.025 13.3 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 CRK42954.1 - 0.12 11.6 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain RSN1_7TM PF02714.15 CRK42956.1 - 1.1e-72 244.7 21.6 1.6e-72 244.2 21.6 1.2 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 CRK42956.1 - 4.2e-29 102.0 0.0 7e-29 101.3 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Aminotran_4 PF01063.19 CRK42956.1 - 8.3e-06 25.8 0.0 1.5e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Amino-transferase class IV PRIMA1 PF16101.5 CRK42956.1 - 0.42 10.7 4.6 10 6.2 0.3 2.5 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 CybS PF05328.12 CRK42961.1 - 8e-28 96.8 0.0 1.3e-27 96.1 0.0 1.3 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit NPR2 PF06218.11 CRK42961.1 - 1.2e-21 77.0 0.0 1.4e-21 76.8 0.0 1.0 1 0 0 1 1 1 1 Nitrogen permease regulator 2 ADH_zinc_N PF00107.26 CRK42962.1 - 6.6e-32 110.2 0.5 9.5e-32 109.7 0.5 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CRK42962.1 - 2.7e-10 41.4 0.0 5e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.18 CRK42962.1 - 0.0048 17.1 0.1 0.0073 16.6 0.1 1.3 1 0 0 1 1 1 1 TrkA-N domain AlaDh_PNT_C PF01262.21 CRK42962.1 - 0.063 12.6 4.1 0.05 12.9 2.6 1.5 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 CRK42962.1 - 0.13 11.6 0.1 0.2 11.0 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain OTCace_N PF02729.21 CRK42969.1 - 1.1e-47 161.8 0.0 1.3e-47 161.6 0.0 1.0 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain SBDS PF01172.18 CRK42991.1 - 2.1e-24 85.4 0.5 2.2e-24 85.3 0.5 1.0 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein GDPD PF03009.17 CRK43005.1 - 0.00015 21.6 0.0 0.00029 20.6 0.0 1.4 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family OKR_DC_1_N PF03709.15 CRK43005.1 - 0.12 12.7 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain Ribonuc_red_lgC PF02867.15 CRK43021.1 - 2.5e-81 273.8 0.0 3e-81 273.6 0.0 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain FGGY_N PF00370.21 CRK43058.1 - 4.2e-47 160.8 0.1 4.7e-47 160.6 0.1 1.0 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain CDC73_C PF05179.14 CRK43078.1 - 6.8e-58 194.8 0.0 1e-57 194.2 0.0 1.3 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal DUF383 PF04063.14 CRK43080.1 - 4.5e-67 225.4 0.1 1.2e-65 220.8 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.13 CRK43080.1 - 2.9e-20 71.9 1.4 5.6e-20 70.9 0.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF384) Ank_2 PF12796.7 CRK43081.1 - 2.3e-38 130.7 0.1 1.6e-09 38.2 0.2 6.0 4 2 1 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CRK43081.1 - 1e-31 108.9 5.1 1e-09 38.7 0.0 9.3 7 2 4 11 11 11 7 Ankyrin repeats (many copies) Ank PF00023.30 CRK43081.1 - 4.4e-28 96.5 6.4 0.00064 20.1 0.0 9.4 8 0 0 8 8 8 6 Ankyrin repeat Ank_3 PF13606.6 CRK43081.1 - 1.1e-27 93.0 4.9 0.004 17.6 0.0 9.8 10 0 0 10 10 10 7 Ankyrin repeat Ank_5 PF13857.6 CRK43081.1 - 8.7e-24 83.3 6.9 0.00013 22.2 0.0 7.9 6 3 4 10 10 10 7 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 CRK43081.1 - 2.1e-05 24.0 0.0 0.0001 21.7 0.0 1.9 1 1 1 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 CRK43081.1 - 7.8e-05 22.2 0.0 0.00038 19.9 0.0 1.9 1 1 1 2 2 2 1 Protein kinase domain Ank_2 PF12796.7 CRK43082.1 - 1.1e-87 288.7 8.5 2.1e-14 53.9 0.0 11.2 5 3 7 13 13 13 13 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CRK43082.1 - 5.3e-74 243.7 6.9 3.6e-10 40.2 0.1 14.9 10 5 5 16 16 16 13 Ankyrin repeats (many copies) Ank_5 PF13857.6 CRK43082.1 - 2.1e-63 209.6 12.6 1.4e-08 34.8 0.1 14.9 7 5 10 17 17 17 12 Ankyrin repeats (many copies) Ank PF00023.30 CRK43082.1 - 1.8e-61 202.0 26.1 9.3e-08 32.2 0.2 17.3 19 1 0 19 19 19 10 Ankyrin repeat Ank_3 PF13606.6 CRK43082.1 - 1.2e-60 194.2 1.7 0.00019 21.6 0.1 18.9 19 0 0 19 19 19 8 Ankyrin repeat Asp_protease_2 PF13650.6 CRK43082.1 - 0.2 12.3 1.9 11 6.7 0.1 3.9 4 1 1 5 5 5 0 Aspartyl protease DUF4235 PF14019.6 CRK43082.1 - 2.5 8.2 5.3 45 4.2 0.0 3.8 3 1 0 3 3 3 0 Protein of unknown function (DUF4235) HeLo PF14479.6 CRK43083.1 - 7.4e-15 55.3 0.3 1.4e-14 54.4 0.3 1.4 1 0 0 1 1 1 1 Prion-inhibition and propagation Pkinase PF00069.25 CRK43083.1 - 0.0024 17.3 0.0 0.0041 16.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CRK43083.1 - 0.15 11.4 0.0 0.29 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase PfkB PF00294.24 CRK43084.1 - 3.2e-21 75.9 0.0 4.6e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase RibD_C PF01872.17 CRK43084.1 - 9e-15 55.0 0.1 1.8e-14 54.0 0.0 1.5 2 0 0 2 2 2 1 RibD C-terminal domain PfkB PF00294.24 CRK43085.1 - 3e-55 187.6 0.3 3.5e-55 187.4 0.3 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase UQ_con PF00179.26 CRK43087.1 - 2.2e-10 40.3 0.0 3.4e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CRK43087.1 - 0.17 12.2 0.0 0.3 11.4 0.0 1.3 1 0 0 1 1 1 0 RWD domain Fungal_trans PF04082.18 CRK43088.1 - 6.1e-05 22.2 0.2 0.00037 19.6 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK43088.1 - 0.052 13.7 5.3 0.14 12.3 5.3 1.8 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 CRK43089.1 - 1.6e-67 227.9 25.8 4.6e-37 127.8 13.0 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 CRK43089.1 - 6.2e-17 61.6 11.6 9e-10 38.0 2.1 3.2 3 0 0 3 3 3 2 Sugar (and other) transporter Nuc_H_symport PF03825.16 CRK43089.1 - 6.4e-05 22.1 9.0 0.055 12.4 0.0 3.4 3 1 0 3 3 3 2 Nucleoside H+ symporter Tox-GHH PF15636.6 CRK43089.1 - 0.002 18.1 0.2 3.2 7.8 0.0 2.3 2 0 0 2 2 2 2 GHH signature containing HNH/Endo VII superfamily nuclease toxin AKNA PF12443.8 CRK43089.1 - 0.01 16.4 4.3 2.5 8.8 0.3 2.4 2 0 0 2 2 2 0 AT-hook-containing transcription factor Fumarate_red_C PF02300.17 CRK43089.1 - 0.032 14.3 1.4 11 6.1 0.1 2.7 2 0 0 2 2 2 0 Fumarate reductase subunit C TRI12 PF06609.13 CRK43089.1 - 0.063 11.7 6.9 1.3 7.4 0.8 2.2 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) DUF3678 PF12435.8 CRK43090.1 - 0.2 11.1 0.2 0.2 11.1 0.2 2.6 3 1 0 3 3 3 0 Protein of unknown function (DUF3678) DEAD PF00270.29 CRK43091.1 - 5.1e-41 140.4 0.0 9.5e-41 139.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CRK43091.1 - 1.8e-36 124.8 0.1 7.8e-19 68.1 0.0 3.2 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 CRK43091.1 - 0.003 17.6 0.0 0.0053 16.8 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CRK43091.1 - 0.004 16.4 0.1 1.8 7.7 0.0 2.2 2 0 0 2 2 2 2 ERCC3/RAD25/XPB C-terminal helicase WD40 PF00400.32 CRK43092.1 - 2.3e-17 63.0 9.2 0.001 19.8 0.0 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK43092.1 - 0.0003 21.0 0.1 0.24 11.7 0.0 3.8 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 CRK43092.1 - 0.07 13.2 0.0 2.7 8.1 0.0 2.7 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region DUF3258 PF11646.8 CRK43092.1 - 0.11 12.6 0.0 0.29 11.3 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function DUF3258 FERM_C PF09380.10 CRK43092.1 - 0.19 12.1 0.0 1.5 9.3 0.0 2.1 2 0 0 2 2 2 0 FERM C-terminal PH-like domain 2OG-FeII_Oxy_2 PF13532.6 CRK43093.1 - 5.8e-35 121.3 0.0 8.2e-35 120.8 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.12 CRK43093.1 - 1.6e-07 31.3 6.4 3.8e-07 30.1 6.4 1.6 1 0 0 1 1 1 1 GRF zinc finger GFA PF04828.14 CRK43094.1 - 9e-10 38.8 4.8 1.1e-07 32.0 0.3 2.9 4 0 0 4 4 4 2 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.11 CRK43094.1 - 0.0042 16.7 0.2 0.0042 16.7 0.2 2.6 2 0 0 2 2 2 1 NADH pyrophosphatase zinc ribbon domain Elf1 PF05129.13 CRK43094.1 - 1.5 8.9 10.6 4.9 7.3 0.1 3.8 3 1 1 4 4 4 0 Transcription elongation factor Elf1 like MAP17 PF15807.5 CRK43095.1 - 0.18 12.0 0.0 0.26 11.5 0.0 1.3 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 LCE PF14672.6 CRK43095.1 - 0.56 10.8 0.1 0.56 10.8 0.1 2.2 2 0 0 2 2 2 0 Late cornified envelope Fungal_trans PF04082.18 CRK43097.1 - 5e-29 101.1 0.0 7.8e-29 100.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK43097.1 - 6.2e-09 35.8 9.5 9.9e-09 35.2 9.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ArAE_1_C PF11728.8 CRK43097.1 - 0.01 15.8 0.9 1.3 9.0 0.1 2.3 2 0 0 2 2 2 0 Putative aromatic acid exporter C-terminal domain WD40 PF00400.32 CRK43098.1 - 4.4e-05 24.1 1.5 0.22 12.5 0.2 3.5 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CRK43098.1 - 0.033 14.5 0.0 0.26 11.6 0.0 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain DUF3258 PF11646.8 CRK43098.1 - 0.12 12.5 0.0 0.34 11.1 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function DUF3258 2OG-FeII_Oxy_2 PF13532.6 CRK43099.1 - 3.2e-35 122.1 0.0 4.9e-35 121.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.12 CRK43099.1 - 1e-07 31.9 6.1 1.9e-07 31.1 6.1 1.4 1 0 0 1 1 1 1 GRF zinc finger GFA PF04828.14 CRK43100.1 - 1.8e-08 34.6 11.7 1.3e-06 28.6 0.9 2.8 3 0 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.11 CRK43100.1 - 0.061 13.0 0.1 0.061 13.0 0.1 2.2 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Fungal_trans PF04082.18 CRK43102.1 - 3.6e-30 104.9 0.0 6e-30 104.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK43102.1 - 6.3e-09 35.8 9.5 1e-08 35.2 9.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ArAE_1_C PF11728.8 CRK43102.1 - 0.01 15.8 0.9 1.3 9.0 0.1 2.3 2 0 0 2 2 2 0 Putative aromatic acid exporter C-terminal domain NOT2_3_5 PF04153.18 CRK43104.1 - 4.1e-55 185.4 12.1 3.5e-27 95.1 2.4 2.5 2 0 0 2 2 2 2 NOT2 / NOT3 / NOT5 family CUE PF02845.16 CRK43104.1 - 4.1e-23 80.7 0.0 4.1e-10 39.2 0.0 2.5 2 0 0 2 2 2 2 CUE domain DUF5115 PF17142.4 CRK43104.1 - 0.013 15.2 0.0 6.5 6.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5115) DNA_gyraseA_C PF03989.13 CRK43104.1 - 0.027 13.9 0.1 20 4.8 0.0 3.4 4 0 0 4 4 4 0 DNA gyrase C-terminal domain, beta-propeller Cue1_U7BR PF18499.1 CRK43104.1 - 0.036 14.1 11.4 1.2 9.2 2.0 2.7 2 0 0 2 2 2 0 Ubc7p-binding region of Cue1 DUF4448 PF14610.6 CRK43104.1 - 0.054 13.3 0.0 24 4.7 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF4448) ABC_tran_CTD PF16326.5 CRK43104.1 - 2 8.7 9.0 13 6.1 1.2 2.6 2 0 0 2 2 2 0 ABC transporter C-terminal domain G2BR PF18442.1 CRK43104.1 - 2.8 7.7 28.1 7.1 6.4 10.1 2.7 2 0 0 2 2 2 0 E3 gp78 Ube2g2-binding region (G2BR) cobW PF02492.19 CRK43105.1 - 3.6e-48 163.5 0.2 4.7e-48 163.1 0.2 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 CRK43105.1 - 4.1e-06 26.8 0.3 0.1 12.5 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase CobW_C PF07683.14 CRK43105.1 - 1.1e-05 25.3 0.0 2.1e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain Septin PF00735.18 CRK43105.1 - 0.0014 18.0 0.8 0.26 10.5 0.0 2.6 2 1 0 2 2 2 2 Septin MeaB PF03308.16 CRK43105.1 - 0.0035 16.4 0.4 2.2 7.2 0.0 2.9 3 0 0 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 CRK43105.1 - 0.0037 17.5 0.3 0.36 11.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain GTP_EFTU PF00009.27 CRK43105.1 - 0.006 16.2 0.1 2.2 7.8 0.0 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_23 PF13476.6 CRK43105.1 - 0.0095 16.5 0.1 0.021 15.3 0.1 1.6 2 0 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.17 CRK43105.1 - 0.0098 15.7 1.1 0.083 12.7 1.1 2.1 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 CRK43105.1 - 0.012 16.0 0.0 0.047 14.1 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.23 CRK43105.1 - 0.013 15.6 0.0 0.025 14.7 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.6 CRK43105.1 - 0.039 13.7 0.3 0.11 12.2 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.27 CRK43105.1 - 0.041 14.4 0.4 0.75 10.3 0.1 2.7 3 0 0 3 3 3 0 ABC transporter T2SSE PF00437.20 CRK43105.1 - 0.05 12.7 0.2 0.11 11.5 0.2 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein TsaE PF02367.17 CRK43105.1 - 0.074 13.1 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 CRK43105.1 - 0.081 12.6 0.7 0.31 10.7 0.1 2.0 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 CRK43105.1 - 0.11 12.4 0.1 0.19 11.6 0.1 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Mob1_phocein PF03637.17 CRK43106.1 - 3.5e-22 79.2 0.3 5.9e-22 78.5 0.3 1.3 1 0 0 1 1 1 1 Mob1/phocein family CxC6 PF18721.1 CRK43106.1 - 0.041 14.2 2.7 0.095 13.0 2.7 1.6 1 0 0 1 1 1 0 CxC6 like cysteine cluster associated with KDZ transposases Fungal_trans_2 PF11951.8 CRK43107.1 - 2e-10 40.1 0.6 3.6e-10 39.2 0.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CRK43107.1 - 4.1e-06 26.8 9.6 7.1e-06 26.0 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GvpG PF05120.12 CRK43107.1 - 0.0015 18.5 0.2 0.0032 17.4 0.2 1.6 1 0 0 1 1 1 1 Gas vesicle protein G Cytochrom_B559 PF00283.19 CRK43108.1 - 0.018 14.4 2.4 0.033 13.6 2.4 1.4 1 0 0 1 1 1 0 Cytochrome b559, alpha (gene psbE) and beta (gene psbF)subunits DUF3983 PF13137.6 CRK43109.1 - 0.13 12.1 0.1 0.22 11.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3983) MOSC PF03473.17 CRK43110.1 - 4.2e-21 75.3 0.0 2e-20 73.2 0.0 1.9 2 0 0 2 2 2 1 MOSC domain MOSC_N PF03476.16 CRK43110.1 - 6.7e-10 38.9 0.0 1.6e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain SMC_N PF02463.19 CRK43111.1 - 1.1e-65 221.2 17.7 9.3e-65 218.1 17.7 2.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CRK43111.1 - 2.4e-12 47.8 8.8 2.4e-12 47.8 8.8 6.4 2 2 3 5 5 5 1 AAA domain AAA_21 PF13304.6 CRK43111.1 - 2.2e-10 40.8 4.0 0.00016 21.6 0.2 3.0 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_hinge PF06470.13 CRK43111.1 - 2.5e-10 40.7 2.8 4.1e-06 27.1 0.1 4.2 3 1 1 4 4 4 2 SMC proteins Flexible Hinge Domain AAA_29 PF13555.6 CRK43111.1 - 0.00013 21.7 0.1 0.00029 20.5 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Tup_N PF08581.10 CRK43111.1 - 0.01 16.1 2.6 0.01 16.1 2.6 7.4 5 4 3 8 8 8 0 Tup N-terminal HSBP1 PF06825.12 CRK43111.1 - 0.048 13.5 0.4 0.048 13.5 0.4 3.6 3 0 0 3 3 3 0 Heat shock factor binding protein 1 INCENP_ARK-bind PF03941.15 CRK43112.1 - 5.6e-19 67.8 1.4 5.6e-19 67.8 1.4 3.0 3 0 0 3 3 3 1 Inner centromere protein, ARK binding region DnaJ PF00226.31 CRK43112.1 - 2.3e-17 62.8 1.3 6.1e-17 61.5 1.3 1.8 1 0 0 1 1 1 1 DnaJ domain Myb_DNA-bind_6 PF13921.6 CRK43113.1 - 0.016 15.4 0.0 0.033 14.5 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 CRK43113.1 - 0.018 15.2 0.5 0.052 13.8 0.0 2.0 2 0 0 2 2 2 0 Myb-like DNA-binding domain Pol_alpha_B_N PF08418.10 CRK43113.1 - 0.69 9.8 14.0 0.14 12.1 9.9 1.8 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal DTHCT PF08070.11 CRK43113.1 - 0.73 10.6 19.6 0.31 11.8 15.9 2.3 2 1 0 2 2 2 0 DTHCT (NUC029) region PDZ_1 PF12812.7 CRK43114.1 - 2.7e-53 177.9 0.1 2.2e-34 117.3 0.0 2.7 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.6 CRK43114.1 - 1.4e-23 84.5 1.3 1.2e-20 74.9 0.0 2.5 2 0 0 2 2 2 2 Trypsin-like peptidase domain PDZ_2 PF13180.6 CRK43114.1 - 2.3e-14 53.5 0.9 5.3e-06 26.7 0.0 4.3 4 0 0 4 4 4 3 PDZ domain PDZ_6 PF17820.1 CRK43114.1 - 3.2e-14 52.5 0.2 2.1e-05 24.3 0.1 4.0 4 0 0 4 4 4 3 PDZ domain PDZ PF00595.24 CRK43114.1 - 1.4e-09 38.1 0.0 3.6e-05 24.0 0.0 3.7 4 0 0 4 4 4 2 PDZ domain Tricorn_PDZ PF14685.6 CRK43114.1 - 0.023 14.6 2.6 2.5 8.1 0.2 3.5 4 0 0 4 4 4 0 Tricorn protease PDZ domain Clat_adaptor_s PF01217.20 CRK43115.1 - 5.3e-56 188.5 1.5 5.8e-56 188.4 1.5 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Ist1 PF03398.14 CRK43118.1 - 1e-60 204.4 2.0 1.4e-60 203.9 2.0 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway VASt PF16016.5 CRK43119.1 - 8.6e-37 126.9 0.0 1.8e-36 125.9 0.0 1.5 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 CRK43119.1 - 1.2e-23 83.1 0.0 2.3e-23 82.3 0.0 1.5 1 0 0 1 1 1 1 GRAM domain ArAE_2_N PF10337.9 CRK43119.1 - 2.4e-15 56.6 0.1 4.2e-07 29.4 0.0 3.3 2 1 1 3 3 3 2 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 CRK43119.1 - 1.1e-08 35.3 14.5 1.1e-08 35.3 14.5 3.9 3 1 1 4 4 4 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 CRK43119.1 - 5.5e-05 23.1 0.3 0.00011 22.2 0.3 1.4 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 NOA36 PF06524.12 CRK43119.1 - 0.16 11.3 0.3 0.35 10.2 0.3 1.5 1 0 0 1 1 1 0 NOA36 protein PLDc_2 PF13091.6 CRK43120.1 - 2.4e-21 76.0 0.0 1.3e-11 44.6 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 CRK43120.1 - 7.3e-05 22.8 1.0 0.049 13.8 0.1 3.0 3 0 0 3 3 3 2 Phospholipase D Active site motif DUF4407 PF14362.6 CRK43124.1 - 0.011 15.1 4.7 0.016 14.6 4.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2681 PF10883.8 CRK43124.1 - 0.59 10.6 5.2 1.4 9.3 5.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Shisa PF13908.6 CRK43125.1 - 0.0043 17.3 1.3 0.016 15.5 0.7 2.1 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator Pex14_N PF04695.13 CRK43125.1 - 0.75 10.4 25.0 4.4 7.9 24.7 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4834 PF16118.5 CRK43125.1 - 1.9 9.5 0.0 1.9 9.5 0.0 2.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4834) DUF4106 PF13388.6 CRK43125.1 - 2 7.6 22.8 0.074 12.3 17.3 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4106) DUF2070 PF09843.9 CRK43125.1 - 2.2 6.4 6.9 3.1 6.0 6.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) FAS_I_H PF18314.1 CRK43127.1 - 1.1e-76 257.0 0.4 2.8e-76 255.7 0.1 1.9 2 0 0 2 2 2 1 Fatty acid synthase type I helical domain Fas_alpha_ACP PF18325.1 CRK43127.1 - 1e-75 253.5 0.0 1.8e-75 252.7 0.0 1.5 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain ketoacyl-synt PF00109.26 CRK43127.1 - 2.7e-21 76.3 0.0 7.3e-21 74.9 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.20 CRK43127.1 - 4.4e-18 65.5 0.1 1.3e-17 64.0 0.1 1.8 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.22 CRK43127.1 - 1.4e-11 44.4 0.0 4.4e-11 42.8 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 CRK43127.1 - 0.0035 17.3 0.0 0.015 15.2 0.0 2.1 2 0 0 2 2 2 1 KR domain ACP_syn_III_C PF08541.10 CRK43127.1 - 0.047 13.9 0.1 0.22 11.7 0.1 2.2 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Ribosomal_S4 PF00163.19 CRK43127.1 - 1.9 9.5 5.9 0.15 13.0 0.5 2.1 2 0 0 2 2 2 0 Ribosomal protein S4/S9 N-terminal domain MDM10 PF12519.8 CRK43133.1 - 2.2e-66 224.7 0.0 2.7e-66 224.4 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial distribution and morphology protein 10 Ribosomal_S19e PF01090.19 CRK43133.1 - 3.1e-39 133.8 0.1 4.4e-39 133.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S19e DJ-1_PfpI PF01965.24 CRK43144.1 - 5.9e-08 32.7 0.0 8e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 CRK43144.1 - 0.00068 19.4 0.0 0.00082 19.1 0.0 1.1 1 0 0 1 1 1 1 ThiJ/PfpI family-like SNO PF01174.19 CRK43144.1 - 0.18 11.7 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 SNO glutamine amidotransferase family Mito_carr PF00153.27 CRK43164.1 - 1.9e-20 72.6 0.3 9.2e-11 41.5 0.1 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein RED_N PF07808.13 CRK43177.1 - 6.3e-06 26.0 4.2 1.1e-05 25.1 3.9 1.7 1 1 0 1 1 1 1 RED-like protein N-terminal region HHH_3 PF12836.7 CRK43177.1 - 0.053 13.8 0.5 0.41 10.9 0.3 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix motif EFTUD2 PF16004.5 CRK43177.1 - 0.086 13.4 2.8 0.12 12.9 0.0 2.2 1 1 1 2 2 2 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus SHOCT PF09851.9 CRK43177.1 - 0.44 10.3 9.3 0.087 12.6 4.5 2.3 2 0 0 2 2 2 0 Short C-terminal domain DUF2924 PF11149.8 CRK43177.1 - 0.97 9.8 3.6 1.3 9.4 1.8 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2924) # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Verticillium_longisporum-vl1.denovo.v1/GCA_001268145.1_vl1.denovo.v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Verticillium_longisporum-vl1.denovo.v1/GCA_001268145.1_vl1.denovo.v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Verticillium_longisporum-vl1.denovo.v1/GCA_001268145.1_vl1.denovo.v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Verticillium_longisporum-vl1.denovo.v1/GCA_001268145.1_vl1.denovo.v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 09:51:26 2019 # [ok]